LOCUS       DAYAOO010000001       123939 bp    DNA     linear   BCT 12-OCT-2024
DEFINITION  TPA_asm: Clostridioides difficile isolate ST8-SSI-h139-18
            SAMN40601845-rid21577343.denovo.001, whole genome shotgun sequence.
ACCESSION   DAYAOO010000001 DAYAOO010000000
VERSION     DAYAOO010000001.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN40601845
            Sequence Read Archive: SRR28438827
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 123939)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 123939)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-MAY-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-MAY-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002157583.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002157583.1
            Genome Coverage       :: 163x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/11/2024 16:19:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 4,038
            CDSs (total)                      :: 3,963
            Genes (coding)                    :: 3,930
            CDSs (with protein)               :: 3,930
            Genes (RNA)                       :: 75
            rRNAs                             :: 6, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 60
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 33
            CDSs (without protein)            :: 33
            Pseudo Genes (ambiguous residues) :: 0 of 33
            Pseudo Genes (frameshifted)       :: 7 of 33
            Pseudo Genes (incomplete)         :: 25 of 33
            Pseudo Genes (internal stop)      :: 11 of 33
            Pseudo Genes (multiple problems)  :: 8 of 33
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..123939
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN40601845-rid21577343.denovo.001"
                     /isolate="ST8-SSI-h139-18"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Denmark"
                     /collection_date="2018"
                     /collected_by="Statens Serum Institute"
     gene            complement(<1..351)
                     /locus_tag="ACGI5H_000001"
     CDS             complement(<1..351)
                     /locus_tag="ACGI5H_000001"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018112542.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine rich domain-containing protein"
                     /protein_id="HFG9695737.1"
                     /translation="MQTEWNFGYNGSPQSVILKPGKYKFECWGSSGGINNSSWHTDAK
                     GGYSKGEITLKKQTTLYIYVGESGYASSSTANNTKSGFNGGGKGYLNQQVMGTYYSMY
                     GGGATDIRLVGGAWD"
     gene            complement(366..905)
                     /locus_tag="ACGI5H_000002"
     CDS             complement(366..905)
                     /locus_tag="ACGI5H_000002"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894901.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9695738.1"
                     /translation="MLNEEVVKKIKNVPNNTNTEIEKVNTNIETAKTELNTKIDQLIA
                     GGSNVASTQTITIDDWVEDAENGFKATVTHSLLTQRIVVNIIDATTKENVVPNFKIVD
                     DNSIEIRSEVKVELNVYVINGNAETHFINATVDDNRVSEMTTYSSKKIEDRLVNIEEK
                     LSGGLSNIATSVNELITYC"
     gene            complement(984..1307)
                     /locus_tag="ACGI5H_000003"
     CDS             complement(984..1307)
                     /locus_tag="ACGI5H_000003"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018112540.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CD1375 family protein"
                     /protein_id="HFG9695739.1"
                     /translation="MIKIDKEKIEKSRQRKELDDLDSSQKTQDNDITDLMLATAEICE
                     MVLSSQQASTMSLKNIKLNEGGSSMAAIYVGLIERGLKTIDQVPVKYREEVRKMCEAL
                     EISLS"
     gene            complement(1319..6598)
                     /locus_tag="ACGI5H_000004"
     CDS             complement(1319..6598)
                     /locus_tag="ACGI5H_000004"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894898.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9695740.1"
                     /translation="MKKNKLLQRGSLFGNKEFKIEEFNKNFDTFNVKDIFTDMDSGSV
                     FIIKDDLKLYAAGYNVFGNLGLGNKVSPIRYFSKIDIDNVKYVSSSGTHSLLLKNNGD
                     VYSTGLNTDGELGLGDNIDRNTFTKINISNVKQIACGNGYSMLVTNDNELYVCGNNKF
                     GGIGLGNTSTVNTFTKIDNLSVKEIFAGVSCSYILTLNNEVYSTGTNSYGQLGLNDTT
                     NRNIFTKVNLDNVIKISTAQGAVNFLLENGDVYGCGDNSSGQVGVGGGATVTVLTKLS
                     ISNVKNIESGRYHKFYIANNNDIYVTGANPDGRLGDKINCDTSTYTPRKSSISIKNIS
                     KIKCAYAISFILTSNNELYMTGNNNYSFSYLKRYDKFIYGFEKFEDFDIEECNHIESI
                     DNRLLINKNDERVLDIGLENNFVNISLVKANDTSTFIVVNGNELYAAGYNAYGGLGLG
                     HNRHCYEFTRVPLELEEGVTIKDIYLNLGSYFTFILLSDNTLYSTGYNVFGVLGLGDN
                     INRNTFTKVNISSVDKISVGDNHALLKTTTNELFSTGLNNYGQLGLNDTTNRNIFTKV
                     STVTYVNEIIAYSNSSYCIDNSRISYAAGYNVFGELSLNDTSSRSVFVKMRYSRYKTD
                     TTVSDVSNIAEIIPFNNGCLIRTTSNNYYVSGRHNYYSTSIKISVTDDYYSRFGEFVG
                     SKNSNANEVAVLIDEPKLSKVLVSNYNLCLLLDASDGGYKEIKFTGRPSTFGASSQDK
                     NLGLRSLISSSMPYYNHYLGTDNLLYTTSKTRMESKFEIRGRNAGGQRGDSSYYSNSQ
                     KYTLSNAFFAYNSQVIYASGLRIVIKDYFGNIYCSGVNSHGCFGIKKPYDVRHDGFVN
                     ISKQFSKKYIISNIKEIKSDRQALYILLNNSEGYVCGNNAGNKLGTIKARSEFIKVPI
                     DNIKEFIPSNDCLFILTNNNQVYSIGTNDLGQLGLGDNIDRGTFTKVPIDNVKKVITC
                     YKSSYILTYDNELFSTGSNGYGQLGLGDDINRNTFTKVNISGTIKDIFCGRYVFIILL
                     ENDNIISLMGCGNRNYISSNTNSNSLTKINIEGLTDPSTISNLMLEEGKTIITMKNRI
                     FVTGYNSLGGLGVGTSYNNSSGYIEGYKDLAFNSNIKEVALGEYTIFVLLENGDLYSG
                     GNADDGIGFNESGTVVLKKLTSNIKHIYANGKNAYYIDNDNALYVFGSRQLGQINNYS
                     DVVQKTPVRNCLNVKQVYTQHNGLIVQYTNNKLEGKGNAVVGQVGIFNGHEENQIANT
                     SSDNPSDLSFSNEMSIIRNNYGLLVNKKIFLHNDDSINYRIPFGTNAGNYSTSLPFDN
                     IKKMSLSSTHSILILENGDVYGCGSNQFGELAINKSELTTTSEFIKINLTNIIDVACG
                     DNFTYFLKNDGSLFSIGKNSEYQLGIGHNDEVNELQEVLTISNIREIYAYSNYILAIT
                     TEGQLYVQGYNINGILGLNENTKNTIIKLFTKVLENVKYIKSYDDKHIFVIKNDKTLY
                     VTGINKETYKIKDVEIGSMLYTFSQIYIPRDVNDIVDALIKDETLYIISKVDSEKTCL
                     EIKNKSYSSIEIDLQNPNNELTKIEMFINNISSSIIEDLSTGTVTFEINPEDLVLGEN
                     KIVFKAHSDIGNNLYINVYIYKKEAGATIVKDSTVLINGNTYNVSSIVDNSQDVVLTL
                     NKGLLEDLNSNNPIYHLVNKLKVQLKINESDTFKDMVKVETRKTKNGYKEIYELKDMN
                     IQSAQPKVIVEEGNTNTTIKKPSMLFNLDVETL"
     gene            complement(6609..8687)
                     /locus_tag="ACGI5H_000005"
     CDS             complement(6609..8687)
                     /locus_tag="ACGI5H_000005"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018112699.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BppU family phage baseplate upper protein"
                     /protein_id="HFG9695741.1"
                     /translation="MKNYEIKNHTIEVDFSNYRINKRLLDYFIYNENDVKTAYIEAIL
                     KNKDEIIDLSEYDRVLVSITKSDGQKVNGECEVVDATSGVVEIELSRQALASVGINTF
                     QLSLVKGNTLINTTNLYYRVEEGMINDDDLTSTDEYGVLLVLISQAEEIIKNNKELTK
                     RVEQLEITILGNEEVRDKAEQIRIYNEDIRNIQEEEREFNELTRQNQEANREESIQNM
                     QIQVDDKLTDCQLQLDEIIDAKSEEIDNIVDDKMLDVQVQTDKKFQDLDTRANSTFDL
                     YDKTFEDKLTDNQEQIDYKLDEVNQAISDVEDCIDESTIKLDTKIKEVDDKIVEVNTA
                     KTDMTTTVSNKITEFENRFEELESLDARGELIQARESVDGTVKDTLKDRLTYDFDKVN
                     EKIAEMTSAATNVAFSKSYVESNWIADGEYFKLIVNHNLVTENIFVAILDEATKKSMT
                     NSYTIVDSNTIEIFNELAINVRVTVVNGNTNKEVIPNTINDNITTLDSTYSSIKINAK
                     FDESLTKINENKSNIATNLDKINLIQSKVGSSELSTVSKNISDAVNELDASVKVLESG
                     GNTNEQLKILKENYNKMSVEILKILFELELDKEATADEAGYWYDTLYDSKNISNLDGL
                     KLNKFKQQLELLSNSGTVLFKNVTVPFLCNKIRYIHDLGSNYSETKTEESYQKGDTEI
                     KINKYSYEVR"
     gene            complement(8699..8860)
                     /locus_tag="ACGI5H_000006"
     CDS             complement(8699..8860)
                     /locus_tag="ACGI5H_000006"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9695742.1"
                     /translation="MEVNMQRAYTIALEEIRGLQNELILYKALNGQLQEEINELRKEK
                     VETKQNKEQ"
     gene            complement(8876..9181)
                     /locus_tag="ACGI5H_000007"
     CDS             complement(8876..9181)
                     /locus_tag="ACGI5H_000007"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894893.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9695743.1"
                     /translation="MAIGKSKLLATGQQVYYWRISTVNISYSNKMAQIKVSGYISEEA
                     RREGLDAVEYENISILEDNFDNYFGINTLDATGKNPLESGYNYLKENIEKFKDSLDI"
     gene            complement(9162..11087)
                     /locus_tag="ACGI5H_000008"
     CDS             complement(9162..11087)
                     /locus_tag="ACGI5H_000008"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894891.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tail fiber domain-containing protein"
                     /protein_id="HFG9695744.1"
                     /translation="MILDNSPADSWIRITGVIVTYNNTLYQVVDKETNKKYIYWDADN
                     PGTLKVSNVRLPEGNTQFLVVVNDNGKHTEVPINSSIFNISFDGNSRKNTEEQIWALY
                     ETDEKHNEKFVVIEKDIDGIHQTVLEVQEDASHIKENMSLIDQRAENVNILVKEVTKN
                     FGGSQENITLRENINKSIIKLNADLGTFSSNMSNYFNDNEITDEEKEKIDIELNLLDT
                     DKASLYTELQKLIDRTTGVDLVAINTSKTALDAASTNLNSIINSVISDSIITPSDRIL
                     AINANAQYNLKINELKNTVDRIYITGMGGSISEEFSQINATAKEIKLEVARVDGVTKT
                     NAAEIKLTKDDITMMVTRNGLGSIVGIKPDKIEFGFNDISNYVEISRSGLTVNQGAIA
                     CDILTTPPGHEPIIRLFGSSRSGFAIDARRSDGSSQASAIRLKYNSNNYFFVGDGGAA
                     IYVDAYENYKFDLNEAKLGANKIEVGSDGNTRMDFSRGHFRFYTSADERADNGIVIWS
                     DGAISFMIRGDECHNFGRNGSKVGGSIEINGTKFGMSPVDSPKFLIEDVLFDVEVEET
                     GTIIKLNNIFAQSILNFAVFSSNANCKVVEKGEDYFKVVGYAGKCDFRIIGKRIGYEH
                     TYYKIMGGEEQHGDWKE"
     gene            complement(11089..12804)
                     /locus_tag="ACGI5H_000009"
     CDS             complement(11089..12804)
                     /locus_tag="ACGI5H_000009"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894889.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9695745.1"
                     /translation="MHFNVNLKQIKSDYTLTIHKMNKSFLGQIPINFLNSIKRELGGV
                     DEIQLTIPKYITDRFLFNKIINPIFEEVKEERLICLNNKEYFVIKNVVTTDDKLKVVT
                     AKSKEVKLGKIDVNIEDYGLQMFTKDEEASIISLNDYLKQETGWKLGYVDDSIAYETD
                     SEGNKREKVRWQESINSNWLDYFNNELKEQFECIADFDTYNNLVNLYHIDSFGDNIQL
                     YLSHDNYIKSLERTTNSDDIVTRLKLEGSEDMNVIGATVTGYDYIENYSYFLDNKEMS
                     EELSRAIKKYQEMNEIREPIWRELIDTKLKKQRERDSKSNEWQMVIEMISKKKDIKKT
                     YDNPQHKDEINSAKIAVEISELEDKKVILDVQIKHLEEEIAKLDESIKDINILCKRET
                     STDEDGYLIFNEVLLDELNEFLYYDTYTNDAFLKVEDLIAEGKRQLSLKCIPTREWTL
                     DVINFLDRIIDINFRQHWKGDLSLGDIIVLHSKESKEEELVYFTSFTQNLKNGKLDTL
                     ELTLSNKKIKEDDKRTIADYLTKAEHATRTLNSKRHLFIQQQKKRINLPDEYIPRKNI
                     QKELM"
     gene            complement(12856..13191)
                     /locus_tag="ACGI5H_000010"
     CDS             complement(12856..13191)
                     /locus_tag="ACGI5H_000010"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894887.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008657 - DNA topoisomerase type II
                     (double strand cut, ATP-hydrolyzing) inhibitor activity
                     [Evidence IEA];
                     GO_function: GO:0042803 - protein homodimerization
                     activity [Evidence IEA];
                     GO_process: GO:0030541 - plasmid partitioning [Evidence
                     IEA];
                     GO_process: GO:0051290 - protein heterotetramerization
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelE/ParE family
                     toxin"
                     /protein_id="HFG9695746.1"
                     /translation="MKWNIFYTKDSHKDLKKLDNSQRKQVLKAIEKVSYNPLPSPDGY
                     GKPLGNKGNNNLTNCFKIKLRGIGIRVVYNLVMENNIMRIIVISVREDSLVYDIASER
                     VKEMATTTE"
     gene            complement(13191..13526)
                     /locus_tag="ACGI5H_000011"
     CDS             complement(13191..13526)
                     /locus_tag="ACGI5H_000011"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894885.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system Phd/YefM family
                     antitoxin"
                     /protein_id="HFG9695747.1"
                     /translation="MLNNRDLLMANMLNTIVPISRFNKGEANKIFDEVKKSGSKIVVK
                     NNIPTCVLITPEKYEEMINAIEDYKLLLETEKRMKNINEEELISQSELMKDLDISEKD
                     LENIEVDFE"
     gene            complement(14291..20494)
                     /locus_tag="ACGI5H_000012"
     CDS             complement(14291..20494)
                     /locus_tag="ACGI5H_000012"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9695748.1"
                     /translation="MDNWNQVKKFQSAWLGGEVLGSASKENERFINSAEGKIIKLKES
                     LKQLVTDTISTDMFKTSLDGLSGITGILNGITKAADKMHVSLPVALAGLSSLFMTIKA
                     LGTGKPITNLGGSIFSAFQNNRKSVKFKDFERATKFTNQYTSAINKNTNASKNNAKSN
                     QVVNRTINSQNGIVGKYTSTTNSLKKATAKEIKINEDRTKSYEKYNQKLKVVSKSRKD
                     TISDGLGNIGKAFAGSSIVNFGKGIATTVGNSLVLTAAFAGVSLLAQAMENYANREEN
                     AYQARKKNIQASKQQINSYESQKVQLQALAEEYDNLSKKENKSKEDNNRLNELKQQIA
                     KIKPDAVIGTDENGIPILKGQVTDLIAEIDRAINAKERLMSYDKHDNAKTAAKKLNSP
                     SKDVNKTLEERMRESETGKLVKIEEDYTAEVEKNKKRQEKAIEKYNNSTGRARDKARN
                     ELMSAKAEEEKIYFKYDEMYRNQVDKIQGYSKEIGDGIFSNIKNKTLYSGLEGNDKSS
                     FAGLESLFDFSEVTPDTLVDTEQAVNKLLTAVRSGKVDVGDLSKTLKDANEEFARTQD
                     IEKYNQTIDKTAKSIAKATNTDANIWENLFGQVNPNGIKDMTSINTLLAKFGKTKLDL
                     ANGDKLAMQLQNQFDSIQNILDTTTITGDVKVDANILTDIKNTKEVPSQVKGMIDALL
                     GTGASTTDVLKFTMDVLMELQTGDPDINKLQNDLDSKFGKGKFTITPEILLSDDSGQA
                     NAEQIISNLKQRYEELPEEVITVIKANPTTTLEEADSVKRIYDKFPKEVKTIIKEEGA
                     DEGGRKILDLTSKYAEVPSELKTKLEADGVGLEKAVEVSEIYKKVPAELKTYFIAEAG
                     EALYNSVNLKDALEHIPDEKITEIYLKQNDGKLGVQDLITSLDKIPLDKDVRINIYKA
                     LSDGDIDALGKAIESLPPDKRVEIIAEIEKAKDDIETISSSEIANKIFTIEVKDLASD
                     AIEWIQKKLKEINGDKDKKDPVKEAKKATKEALKDKQNPKGYAFSKDKEAEKLVDDIL
                     NTPPTKQIELKLKKNEELRNTLNSFKQLEGRNDVKLKLESSGIETEQVKIFADIVKNL
                     PTNSTFTNKFITDNVDSLKNLKDYEAVQKWLMDNPTIAMDYSINLNGLDDFDKMKSIY
                     DGLEDKKDKKVFAEVIIKNPEKAEAFQKLYDNVPEETKSKVVSFAVENADELERATKL
                     YESTPDEQKNQVLNFMLNNEDKLYLIEQLYNDFPESKDIIANLIVNNPDALDEVENLN
                     ALDLDKDVKINIIKSLTNGDINSLIAEIEKLPPEKQVEVIAAIEGAIEGIDSVDKKTI
                     KDKWAKLKANNSAALETIRQTENKKLSDKSFTITAHLRTVGTLGGIASQFANNILGGL
                     KSDRKSVQSINSIETPQAIPANLSAQPRTSEPAPISDETPVTKPSLFSRTVSRATSPI
                     KTLTEKFSRITKTPKIALDTKSIDAAVKYSIELLKELENAISKVTDRISLLDKKMKYS
                     SGKDKLKYLEEQNALYKEELTLLDQKDKALNTQKNRLKDRLKKDYKYTFSDDDNLTSY
                     EEKLISLEKELEKLDKQSESDKGSKKSEERKKKIEEEKKVVEEYLKIAFTEIPKVADA
                     QQEVTNSLIESTRAAEEFKKELKEIAREADLTSAQKHVTEIQNEIDLIDILMKNAEGD
                     EKLDLIEKKKELLAKQAKEIKDVIKVYEDTAKELREGLSKEGFEFSADGKDIKNYGQQ
                     LEFLKNNKDADKYKEIEENAKKYLDLLLKDLPDANNQIKQNKEEIENLNKEIQDAYKE
                     QLKEAQSLQEKIRDMYKKELEERLKEIDKETKAKIDSLKKQQDAYNDSRKEAKYKDDY
                     EEQQDVISDLEKQIAIAERDSSLSGQKKLKDLQKQLKEEQKKLQDLVQDHVDDQVNDM
                     YDKESDRLQEEADKLKEELEKKYSDENLVDLINEAISSGKFVGLDGEVKKLQDAIIEY
                     INKYEDGMLAMGSVTKQEWLDRLKEGKDTLEDINDILDELDLSKFAMPNYNPPSNSRS
                     RSTSPISAVNYNSPFVVVQGNVTKDVMPEFEKKMRKMIEENNKKIISNTRS"
     gene            complement(20804..22687)
                     /locus_tag="ACGI5H_000013"
     CDS             complement(20804..22687)
                     /locus_tag="ACGI5H_000013"
                     /inference="COORDINATES: protein motif:HMM:TIGR01760.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005198 - structural molecule activity
                     [Evidence IEA];
                     GO_process: GO:0016032 - viral process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail tape measure protein"
                     /protein_id="HFG9695749.1"
                     /translation="MAEEFKIKTSIELDDKKARKQLASLKTSAKENNIKLNVEMNASS
                     LNNLKQLENTLKQINKLSRETQNGLFGGKGNSNGNINKLTSQYDNFRKKIESTQRQLK
                     KFTQTNILDNKQIGEINKLSGELKRLSNIKLGGLNSKALSDLSNVQSKLANMKIPDMN
                     TKMASQFKTLQNEAGKLANKIETLGKSGYADTSKLQALSNSLKSIQNLNLKNLTSNQI
                     QSEIQKLEQLKNKVKEVENATKNTKLDAKFNMNLSKVISDLNRLRQKCLELGQSTAGI
                     DKLEKELMQLNGMPLGQKVKELDSIKSRLSNMKSNFTGLGTSVKATNGFFSDLYNSMR
                     TYTLGNMIGMSITNGVRNIKTTIVELDSALRDMMKVAPDNFEGTSEQLKNVKNEAISI
                     GKDTARASEDIIQGASKALQTGVKSVSDSLKIAKQSAVFANVGDLDQETADKYLTSVM
                     SAYGGMTKALKPIKDTRVQIKGMSKDYDNLTKFLDLSNYAGNNFAITTGDVGAALQRS
                     ASMLSSAGVSMEDSVALIVGGNESVQNAEKVGTALKTIGINMSGIKASADSGKISLNK
                     TAKTLQETAKINVLDKQTGQVRDMMSILDELAEKWHSVGEDALTKNQKSGIAEAINFS
                     RLI"
     gene            complement(22746..23456)
                     /locus_tag="ACGI5H_000014"
     CDS             complement(22746..23456)
                     /locus_tag="ACGI5H_000014"
                     /inference="COORDINATES: protein motif:HMM:NF021378.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SHOCT domain-containing protein"
                     /protein_id="HFG9695750.1"
                     /translation="MEEYLGHFILIGLGVGYIIVYCFIRNVMDNAKEKEARLERIAER
                     NREKTKVEKAIQKNISMAKCQAFGNSNSDSVILSNNGKISIIHAGFKTAVKKNIEDLV
                     SIKFSMQVSEKNQMRIISIVPTYDKYTFVEKIYLTLIFELNTYEVFYIPQYKNINNAD
                     IQEKIKEMERFKLVVENEAAKFKNAKIESNNDIKKDDDDISKISNSLKELQSLKDQEI
                     LTEEEFNEKKKVLLEKIK"
     gene            complement(23516..24676)
                     /locus_tag="ACGI5H_000015"
     CDS             complement(23516..24676)
                     /locus_tag="ACGI5H_000015"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9695751.1"
                     /translation="MLISEYIKDNRCGKKSKLYFKKLEEIKQEFINRDLEYLLLTTWD
                     EEISCMMKTGRDLDKLKYRDGFKEINNLFDSISEEIRDEYKEKDTYTMFFSSCSKEKY
                     YIACELANSAYKHIILPNIFEDDKSVNHKVVFKKEQKKEIALMLKLISSYMQHGFSGY
                     KIYDTDIKFIENLCLFEGKKVCYPKPNNLTHFLGDISRSDNDPIEILHARNVINKIME
                     KGYFDNEFELVYFLRGKIMTPMQNKYEKIDTSSLEKINYLEEKALIQKKMILNDEMAY
                     KWKSEINMFKVICKKFKDATHQYRPEWLNGQTLDVFVPSINLAFEYQGQQHFKSVDFF
                     GGEETLEKNKLRDKKKKRLCDENNVKLIYWNYDEPITTIVLKKKLKENNVEL"
     gene            complement(24777..25820)
                     /locus_tag="ACGI5H_000016"
     CDS             complement(24777..25820)
                     /locus_tag="ACGI5H_000016"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894869.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage antirepressor"
                     /protein_id="HFG9695752.1"
                     /translation="MEIINRENEKRIISFNNELFGEIRTIRIENEPYFVATDIAKALG
                     YKDTTNAIKQHCRWVVKHHIPHPQSKTKTLEVNIIPEGDMYRLIINSELPSAEKFERW
                     VFDEVLPSIREHGAYMTNEALEKAINDPDWTIKLLTELKKERATKEKLKVEQEKNKPK
                     LELANAIESSSSSILIAQLSKILNQNGVDIGQNRLFEWMRNNEYLIRKKRADHNTPTQ
                     KSMDLKVLEVSESTGIDKDGNTVIRQTPVVTGKGQIYFVNKILKENNKVLKRFMINND
                     YIRGVMVEIGKTYAIYDHEYYGFIGILKSVRNEKIRVEKIGDVSSSRDIPICMIDYIE
                     EASKEDINKYLSK"
     gene            26081..26530
                     /locus_tag="ACGI5H_000017"
     CDS             26081..26530
                     /locus_tag="ACGI5H_000017"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894857.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HFG9695753.1"
                     /translation="MFGERLKKLRIKFGLKQHELAEILNVSQSTIGMYENDQRTPPAE
                     SIVKLAEYFNVTTDYLLGHTKTNYSVSANIPGMPSIICEDTSIYDIVDEKKDIKSLED
                     INKFLENNNYNDEVKEVLKKYIQLDEMDRKAIDRMIDNAYERLKEDN"
     gene            complement(26666..27499)
                     /locus_tag="ACGI5H_000018"
     CDS             complement(26666..27499)
                     /locus_tag="ACGI5H_000018"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9695754.1"
                     /translation="MTIKDFQEKSYVAGANLEDIADTIQTYWKENIYEKKHGSNIDAA
                     IFAAMLDKSDEIEKSKKYDDELLKIYSKLKSVPEGSEDLNDILSTIEKFYNSYTDFHS
                     FATEPSGSYVDYSASNNTKTDEFLSNYRALENSIKSNSELNKAKSTSETMMMNIEKAM
                     KEYEIISDSIPKDIDPLDENLYEKVKKIVPDFYSDKNIDVSYIENNKGKFKNDERVSK
                     ALDHFSAAKTSYDNMVKYAKAYKKSNSQDDLEKFKNEIFDFRAYVAIYGLQVEYSDEE
                     N"
     gene            complement(27513..27752)
                     /locus_tag="ACGI5H_000019"
     CDS             complement(27513..27752)
                     /locus_tag="ACGI5H_000019"
                     /inference="COORDINATES: protein motif:HMM:NF024637.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc-ribbon domain-containing protein"
                     /protein_id="HFG9695755.1"
                     /translation="MSEDENKVSQENDSTKFCISCGEKLLEGQLFCSKCGKKVDEKTV
                     ISKKASINKNCWYNIDGHSGDFHQYQYQGKKTTRS"
     gene            complement(28197..28997)
                     /locus_tag="ACGI5H_000020"
     CDS             complement(28197..28997)
                     /locus_tag="ACGI5H_000020"
                     /inference="COORDINATES: protein motif:HMM:NF024098.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3800 domain-containing protein"
                     /protein_id="HFG9695756.1"
                     /translation="MGKIYNLYLDESETHDEKDGNWINKVFCIAGIIVEDKYDCNELT
                     KDLNKIKYQIWKDNINYEALILHEVEIKQANNGYDKKNQNLVKPHNRIFRKNQNVKIL
                     YRGLEKIIRNKKITTLAVCIKHDELDKLYNKEIQNDRTLMALQILIENYVHFLKNNDS
                     KGRIIYEHNGDSNSKIMKMKFNMIKTMGTLFINPYAIQERLLDIEFPSKDENIAGLQI
                     ADFIPNIIARKVSNKKLNKYNIYNTIKRFSYDGNVKNKDKFGIKIIKL"
     gene            complement(30183..30623)
                     /locus_tag="ACGI5H_000021"
     CDS             complement(30183..30623)
                     /locus_tag="ACGI5H_000021"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894846.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9695757.1"
                     /translation="MVFKSLDELVAYTKNKIAASMPEVGKEMKEIMKEEVNKQVYSGY
                     TPVGEWNPNVWGGRTGQLLDAIDVTELSSNSVTSEIQNNGNWVDAFTRNSAFPMERLE
                     KGKVWGVGGYRPQTNIMEESNSKAQERVPKCFKSKMNELGVPVK"
     gene            complement(30624..31082)
                     /locus_tag="ACGI5H_000022"
     CDS             complement(30624..31082)
                     /locus_tag="ACGI5H_000022"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009900754.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9695758.1"
                     /translation="MNKIQVDKLIQDEVRAIIPIIDENGKEEYIEVRNPDKETKEEIL
                     NKIWVGMENPDLALSQEDILKMLIDKLTNIELNIEIEDLVDSNISSELETVMYHICQI
                     GNELTASLLMNTDVKLGQMKNEILQDRVLKEIEETEEIEKMNNIKDKVVN"
     gene            complement(31096..31881)
                     /locus_tag="ACGI5H_000023"
     CDS             complement(31096..31881)
                     /locus_tag="ACGI5H_000023"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009900751.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail domain-containing protein"
                     /protein_id="HFG9695759.1"
                     /translation="MVFLDDKFLFDNVSSESMNIKLVTLGDDEILNEYGLPYEEAIKS
                     DSSFNKNPCYSEDETTIEPITLQFCLCSEHGEAYEWDDYTLENICNWFWQREFKPFIS
                     YDNIEEIYYFKARKIIKRYTKDKKGVLEIEFQPYTNYAYRSFQKVITVKDTREIKLNN
                     VSNVDEEYAPVIDIECLKEGDITIRNSTISDNEEDNLVISGLELNEKITIDNLYYTVL
                     NSNGENRFNIINRKWIRLRRGVNILKFTGNCKVSIKCKYPIIK"
     gene            complement(31980..32798)
                     /locus_tag="ACGI5H_000024"
     CDS             complement(31980..32798)
                     /locus_tag="ACGI5H_000024"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894841.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9695760.1"
                     /translation="MKRFAVKDAGNVIVKNKVTGEVLFYSQDLNAFNFKMDSESVYAK
                     AKGANTIAFDGAITASLTMEQEVIQMAQLAMLLSSDIDEKTAKVGKRKVLTSDSTKKV
                     TLENIKPVANSISVYSIESDGISIIKKLQFTSSVTGANTEITISTADFNAGDKVAVFY
                     LEEIPKAKVVKIKEESTAPNYVVEAEVMVKTVDGEYMVLYMSVPNAKAQRSIELNLTA
                     ENPSGFNMTLDVLPDENKEYATFTFIGDENLNPARMASMLGVELEDEKDTKPKK"
     gene            complement(32843..33619)
                     /locus_tag="ACGI5H_000025"
     CDS             complement(32843..33619)
                     /locus_tag="ACGI5H_000025"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018112681.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9695761.1"
                     /translation="MLENYYITGLPIKLGETLGTVYQPTIEELIKFDMANLEIVNPFL
                     VLEKSYSQLCNEKIFELKCKYDAIPILDSSEEIELLSDKIKKSLSILYKTDIKNIEYM
                     NNIKIGILIKFDDKKKNAFISREDFGLVSDLILEMFCIDKKNLFKDDEDKWIENTGSE
                     REKQLIAHFKEKERKKREKEAYHLCDYINVVQNIDGYVPIDVILKMTYWQLINVYKTK
                     IQFKNYNESLGYAWSFKYQTDMDKMKHWSKEIKIPLSTVK"
     gene            complement(33619..34068)
                     /locus_tag="ACGI5H_000026"
     CDS             complement(33619..34068)
                     /locus_tag="ACGI5H_000026"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009900745.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9695762.1"
                     /translation="MSNQDFAKFMIYNDESQKDILSMPDIKNPVKELRNKKVFLNRRV
                     EKVLKEADISVFIIMSEYRPCFEGSRTIKKTKIEIGVVCHDECQSTANGLRDVALVCC
                     IVDIVTQNEEIAGIGKIKLENVYQMYNLNTDYNGFVITVSAESFGDM"
     gene            complement(34128..35117)
                     /locus_tag="ACGI5H_000027"
     CDS             complement(34128..35117)
                     /locus_tag="ACGI5H_000027"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018112679.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9695763.1"
                     /translation="MSYLSDTKKRIGLGCSTPKEKRILQLRLSFKKYLKETPTCIEVP
                     ITDIDEICITEDTKRAIVAINDITNNDKRALDEKNLLVESDLDVDVGCYLFYDNCYWL
                     TIFKEHKEMDTYKHFIIKRCNQFFNYKYKGQMYKIPIAVENLTLYSDGMADNKYTSIS
                     DTKRQLYFGSNPVTKTIDIDTRIMLTGKTVFRVTSINDFEYNGRETGADGLIKAICLQ
                     DALISKDDTINNIAWNDLSENESVIIPFSKIMGDGFINLGEENEYKIDHSQGVEWLLD
                     KQYGYCNIINQDEKKCVIQANTLAKYSGFEALLLAKDKDTNKTIDTKKITLRG"
     gene            complement(35119..35748)
                     /locus_tag="ACGI5H_000028"
     CDS             complement(35119..35748)
                     /locus_tag="ACGI5H_000028"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894826.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9695764.1"
                     /translation="MGTPLVKIYKKFLDGINDEEMLLLSNEIIEKMMYSYLEDAIVDF
                     NQCKKDLTIKYVDEKGGEIIPAAQLSYTSNYSNKNAEITLMGKDTKEEYELDKDYTIS
                     FEDEKFIISFVVETTEEIIFKYKYLGEIVSDLDLDEIKILSYGMQIHWLQPKINREEN
                     LKQMLTDSDYNAKSGANMLAKLQAREEQLRTRFNKYQQRYMLKNFEGWN"
     gene            complement(35763..36395)
                     /locus_tag="ACGI5H_000029"
     CDS             complement(35763..36395)
                     /locus_tag="ACGI5H_000029"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018112677.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9695765.1"
                     /translation="MARAKKENISKTEVKVNTLEKDIKSTLNKKEARLNRLELQRKLK
                     QKKQEIDIEIKNISTWDVDYIDPREKQQIFSLSKVGSKDSTEFIDLDTLYRIVRRSPG
                     FFEEHRLIISDVDSLDVECTPMDIIDFLGLNSLYEYIRNPNEDYLEYFLSDKVDINSF
                     EKILNKNNVELTRRLAERAIDLHKKKKFDSGLKAKLLAKRIGMEDLYLFS"
     gene            complement(36449..37459)
                     /locus_tag="ACGI5H_000030"
     CDS             complement(36449..37459)
                     /locus_tag="ACGI5H_000030"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894822.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9695766.1"
                     /translation="MATAKTLKRIAHELYTDTFREYTDRDGNTITYRDAESAIKNKLK
                     EMMGGEKYNYYKFQENKWGFYNLISELISDDINRLNEEVFSPFCDFENFDLGDKKEFT
                     VENTNLFKVANIADGVNSTRRQRLLNKKVPTTAFKLSVAIYEEAERFITGRINWVVFV
                     NRVSDSYHYDIARRIAKTFEGAYSTINAKFQATGNSDKVLLELIAKVEGATGKKPIIY
                     GTPLALSNLEGVQTDLEKEEKRKYGFIQTFRGGYKVLSLPNAYDENAAEGKEWALDNK
                     AIYVIPDGEKIIKLGTEGDVLVIENTDEKERDDQQIEYFMAQKIHLGVVTAAKFGVYK
                     IQ"
     gene            complement(37547..38044)
                     /locus_tag="ACGI5H_000031"
     CDS             complement(37547..38044)
                     /locus_tag="ACGI5H_000031"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894820.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9695767.1"
                     /translation="MKKDKAIIQTDKVKNPDVLTGKYVVPSEDTNPINLENGAVINIG
                     ELEDTEYGRDTHKIYKVTNDTLDWGIVDDPATMYDERLDERDYEVSPGQICRCRRLKK
                     GDEVTISLLHIADKSIAVKDKLQLKSDSFQFEKLPTADAKTPVAEVLELWNYEGQDSV
                     TIKVL"
     gene            complement(38059..39492)
                     /locus_tag="ACGI5H_000032"
     CDS             complement(38059..39492)
                     /locus_tag="ACGI5H_000032"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018112676.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9695768.1"
                     /translation="MKKIKILKLPCNLKHYSDKKKLEELNSNLLPVYIYVMHEGTNPN
                     GTKFYEEAIDKAEPTLKNVPILGYVKINEDGKYDFDGHNVLTQVVQTDEGFILEEYYE
                     ERIIGVIPETNKYEKVEIDGQKYVKCKGYIYKSYSNHAYDIIMDSDEIEISMEIDIND
                     YQLDDSDGFYNIKDYVYHGITCLGSDVKGAMGSNCCLTKFSRKINYKEEISKICSEIY
                     ALEHGEGEKNLPNKNQKLNKNSEGYALAVSNLSTEIRNKLKEYKVETENWYGEKVEVQ
                     AFYYNDLIPEENIAIVEDEINWGYYYGIPYIVNEDAVILDYENKKSYIQTWREKQEGE
                     IVQVFSRQEKLKKEIIEKFTEKQKEISNLKASLEPLQAFKEEKEFELFKSKVDDVAQK
                     FELAEDEIKDIKIKAYNKEITLDEYKKELGYIFALKTLSNKQSEKENFSINDDKNNTI
                     KIPISNNNDSFSEPEEISFIKKYSDKE"
     gene            complement(39499..39690)
                     /locus_tag="ACGI5H_000033"
     CDS             complement(39499..39690)
                     /locus_tag="ACGI5H_000033"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894816.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9695769.1"
                     /translation="MSKFIYAFSEDDKKLLMEKGYRFICENKLNNKTLYVFENKSKLI
                     NNFSNEEMKRFIFTSKIRF"
     gene            complement(39693..41171)
                     /locus_tag="ACGI5H_000034"
     CDS             complement(39693..41171)
                     /locus_tag="ACGI5H_000034"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894814.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9695770.1"
                     /translation="MGKKNNNKSKSKDNNSTQNQINMLNAQIGKYASVKESTTLATEM
                     YKLRSISRDKLRKALSNPYQISNTDILQDASMILKATSGTYRRVLNLISNMNTFDHIL
                     YPKDISRLKTKEKITKAYMNSASQLEKYNIKFTSAWITEKVLELGEVYLYKIEDNSGM
                     VLQQIPAKFCMITMIENNVMRYAINIKKLTDKNIISFPEEIKNIYKKYKSNLLTREEL
                     IDNTYFQLSDKAVAFNYDLDSVKGVPFFCFIFDDLMELEDMKDLKSTNAVIESIKLIH
                     QKIPFGKNDEPLVDLNLIPIYHNSTKANLPKGTAITTNPLELETHTLSDGKSKINDYV
                     KEAKEFIFDNAGINTALLNSDKINNESILNGIIADSLIPMRIQQMIENWVNFELNKDK
                     KANLFNMKFIGTTHFNKMNLSKQYREDMGYGGSKSLFIASTGFTPLQAINTLQAEKLM
                     GFDEFLIPQQTSHTQSSGRPDKSDIGTDNGNSTQAKGNGEND"
     gene            complement(41188..42936)
                     /locus_tag="ACGI5H_000035"
     CDS             complement(41188..42936)
                     /locus_tag="ACGI5H_000035"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894812.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9695771.1"
                     /translation="MRTKYEKRELSSNDSSRNLLESIGEYWGAFYLANPHRFCMDYFG
                     FNLHLFQQILIYMMMKSDQFVFIASRGLGKSWLLGVFCCVIAVLKPGTCVLIAAKRKK
                     QAKLLITSKILGDLYLKSDTLKREIKSFQVNAQEVSIDFWNGSRIEAVVSNDDARGYR
                     ANVLIVDEYRMVDEGTVNDVLVPFLTNPRQPGYLQNPKYRYMQEENKEIYLSSGWYSQ
                     HWSYKKFMETVKGMLSGEDMFACSIPFTCSLEHGLLTKKRILKEMKKESMSDASFMME
                     YCGVFYNESDDAFFKSSWVNPCRVLESMFYPPSDIEYLENKKKRDKKYHLNKIKGEIR
                     IIGADIALARGVKNDNSIYTLMRMLPNEGTYKRCVVHIEAYNGMEAEKQAIRLKQLFS
                     DFQADYMILDTQGIGTTVWSYIQKANYDSDRDEWYDAYTCFNEDNTVDKSLAKKSLPV
                     VYSMKAYADENHKMAMSLRDVLTNRTLELPISDIEAKEMILEKEMIKADEIDKKAELE
                     AKYIAPYLQTTALVNELINLEYSADGGKIKIKEKSGARKDRYSSLAYTNFLADYLEEK
                     EKRKNRNNQKTVMIYW"
     gene            complement(42926..43825)
                     /locus_tag="ACGI5H_000036"
     CDS             complement(42926..43825)
                     /locus_tag="ACGI5H_000036"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018112675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9695772.1"
                     /translation="MAISKTKCLNCGEEKYTDRYFWKSHSEIFTLNKRLPVCKECFRA
                     RFLLLNGCYNGELVKALKHICFNFDVYFDEKLAKELADKKNKDELIDEYMKIINRNSK
                     YKGKTSLDNLLKEIYTGNNNDKNIVINDEIKLKWGRGFDDYEYKILERKYKEYKEYYE
                     PESLTERKLFEEICIIELEKDKSREKGDMKAFNDLSKLVSSKMQDAEIKPSQKKKAGD
                     SQDDTFGMKMMIYEKNQPVKDRLKEYEDVDGFEAYVNKHMKKPLAVALGLATGKYSIN
                     DGDKDIKFKDDVRDILEGNKNED"
     gene            complement(43956..45155)
                     /locus_tag="ACGI5H_000037"
     CDS             complement(43956..45155)
                     /locus_tag="ACGI5H_000037"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894808.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9695773.1"
                     /translation="MEDILKKKEDESLVDYRIRIRLAKVNKEIDLDWGEIVELLGLEC
                     SPDHCRKVSYGLKEAFDYLNSKIQNNSTQEEIDKINEKILELKKIKVQLSDERSLVNK
                     KIREYSRIDNIIDLFNNKIDDISLHKPFLSDSSYKCYESSNQEAIMLISDIHYGLETI
                     NAFNRYNSKIFKIRIQYLKDKIIEYSKLHKVKRLHVMLLGDLISGYIHNSIRLENREN
                     IVEQIIEVSEILSEFIYELSKEIDKIIIYSVGGNHDRVLPKKDENLDKDNFTLLIDEY
                     IKLRIKNINNVIFQENIYDNDIIVAKICGNTCFGVHGDKDKMSTAIPKLTSLIKLIPD
                     YIFMAHLHNCKEDNYGESEICVNGSFSGTDSYAKNLRLSSHAMQKLMIFNESGRICTY
                     NINLSKL"
     gene            complement(45232..45420)
                     /locus_tag="ACGI5H_000038"
     CDS             complement(45232..45420)
                     /locus_tag="ACGI5H_000038"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009900721.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9695774.1"
                     /translation="MKNNKGTVLEKCEIIKQENNTYKIIEHLKDGDHEVLLSDVLDKY
                     TGDTDLNITIRLSETIVQ"
     gene            complement(45790..46407)
                     /locus_tag="ACGI5H_000039"
     CDS             complement(45790..46407)
                     /locus_tag="ACGI5H_000039"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894800.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9695775.1"
                     /translation="MVKYNVHKALAEKKLLEDKIDRCISNFKIVGTKKGSDKNVYETK
                     TSVEDFNVEVSSKYQQIEDLIYNYNALDKAINISNAITNVQISNKNYTVLEAIKRKNS
                     IELDKSLLRQMVSNYDCMMSEVNRRNEEVQKNTDRMFEEKEKSKDGAELISFYKKQQE
                     WSLVDPLKVREKIEKLRDEIEEFEKEVDFALSTSNALTIIDVDLR"
     gene            complement(46463..46553)
                     /locus_tag="ACGI5H_000040"
     tRNA            complement(46463..46553)
                     /locus_tag="ACGI5H_000040"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(46518..46520),aa:Ser,seq:gct)
     gene            complement(47169..47447)
                     /locus_tag="ACGI5H_000041"
     CDS             complement(47169..47447)
                     /locus_tag="ACGI5H_000041"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894798.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0030527 - structural constituent of
                     chromatin [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="HU family DNA-binding protein"
                     /protein_id="HFG9695776.1"
                     /translation="MKKVDFLKEVAEELGVSQIRVREILDVIEKKRNEVLQDGEELTL
                     MGVKYLTKIQKGKEGEITLKDGTKKPWKTEEKRVPKLKIAKSLKDAII"
     gene            complement(47581..49023)
                     /locus_tag="ACGI5H_000042"
     CDS             complement(47581..49023)
                     /locus_tag="ACGI5H_000042"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018112672.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9695777.1"
                     /translation="MIYNNNNFYEEIDGKSAQDYIKNLDYSIDNSKDRIKYIEERLGV
                     KHTWFEESNRNYIDTFYNTLTKRNENIITRVKYQEKKQFNDKFWENIFEQTSDSPLDK
                     DGVYYVTIDGEEVVMDYNRFITWCGYNQINPIEYINVKNPFSNSNGTWEYTHHNTSKI
                     KLILNKDDSIYSTSNIAKTLEIMGSYILSVDDKPKETKIRIYNSKELFNRACQEEALL
                     NKIAPANGGNINSNTSNKDGFLEDNSFAFFQLPKNYKKIKDIKVKPKDIKKYPIIKTY
                     SDTYEWYKAKYKELGHKQLSKEELKLKRMVRKNLNALKNDMTDVKNSIERPIIWKAPL
                     ADAGSPEWDYLDMFDKSHVKELLRIQKGNDLQDDLTCIVMDLNNIISKIEFTTVQKDI
                     LNLYRKDKSLEFISNLMNITPQAINNQINKIVNKIIDAYEKNYEENYYYISVCKGKYK
                     KCSRCGKIKLLSRFDKNGKKGYRSNCKNCN"
     gene            complement(49026..49274)
                     /locus_tag="ACGI5H_000043"
     CDS             complement(49026..49274)
                     /locus_tag="ACGI5H_000043"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894792.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9695778.1"
                     /translation="MKEKKIELIYLEDLDESEKTGVHKNRYQILNEEYEQMIDTYTEM
                     SKRSSYDIVNERHKEDFKDELWDYDDTDYDDGLQGKEV"
     gene            complement(49452..50315)
                     /locus_tag="ACGI5H_000044"
     CDS             complement(49452..50315)
                     /locus_tag="ACGI5H_000044"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9695779.1"
                     /translation="MKRGEVLEIGKRKKSFSPEQRAIINNKKELPYHNFKLGGFVFCT
                     YVKNELLFNEVNISKANISRLIYLATYLNYNTGEENLLVRYSQFKEMIPIDRKNMREI
                     LNLKDRAFRNFLADVKKCELLYESNNKFYINPKYFTKGIPNFENKEYTRIYINTSRFL
                     FEHCTPRQHKQLSYIYQLIPYIHFESNILCLNPHETDISKIKKISLYKICQLLNISTI
                     KQDMNKFKKELLRFYIKVEDDKYYFFKYVIVEGNNKNTDYFIINPCVIWKGNNLNLAK
                     KTIDLCFFNCI"
     gene            complement(50587..50859)
                     /locus_tag="ACGI5H_000045"
     CDS             complement(50587..50859)
                     /locus_tag="ACGI5H_000045"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018112670.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9695780.1"
                     /translation="MKKSSSFYLEEDIFGEIEKYQNDKNISSRNTALERIILEWKNLQ
                     EENKLLKQCLGNGVYRTNKKTNVTEEKKDIKRENPIIKNIFNNMPD"
     gene            complement(50872..51786)
                     /locus_tag="ACGI5H_000046"
     CDS             complement(50872..51786)
                     /locus_tag="ACGI5H_000046"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894786.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9695781.1"
                     /translation="MEENYQVIGLDIGRGYVKGYSKYNGMVKECLFKSVFGDGRNIDF
                     EKYENPIYIDFESVSYFVGSLAEKESITPIRNSDDSKVSFTMRILVAAALNEIAVADE
                     VKLMMGVPYKSFRKTTLKEVVDTYKGKTFKVKDKIKGGHKEIKISDISIFREGDAALF
                     HTLEGKVNEDKAVGMVSIGFRSTEMSFFEKGFVFNDKLSDTLEAGNQDALTMVQKQLK
                     DRGIIRELNEIDSSNDYDELKKVAYIMASESTAQRISSKWKNIDEMDVYVSGGTALHM
                     TFDNRFKVSKDAQMATAKGLFEVGMEQF"
     gene            complement(52208..52396)
                     /locus_tag="ACGI5H_000047"
     CDS             complement(52208..52396)
                     /locus_tag="ACGI5H_000047"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894784.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9695782.1"
                     /translation="MESGLFVSRILCVVLSFPHFKKIADGFTDEIALYFPHKTNIYLK
                     IFLRFLLLNYILNKENIK"
     gene            52892..53050
                     /locus_tag="ACGI5H_000048"
     CDS             52892..53050
                     /locus_tag="ACGI5H_000048"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894781.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9695783.1"
                     /translation="MRITKGKIKELIELCHQLEKLFVQVFKSLEHILISLCSCIGWLL
                     ILIYIIKH"
     gene            53303..53494
                     /locus_tag="ACGI5H_000049"
     CDS             53303..53494
                     /locus_tag="ACGI5H_000049"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HFG9695784.1"
                     /translation="MKLEKLIDIRKEKKYSQEDIARMLDISLRNYHRKEKGENQFTVS
                     ELEKICSYLDIESKELLDI"
     gene            complement(53708..54019)
                     /locus_tag="ACGI5H_000050"
     CDS             complement(53708..54019)
                     /locus_tag="ACGI5H_000050"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894777.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HFG9695785.1"
                     /translation="MNRLKEVRKERGYNIQEIADKLNVAYNSVLRWENGNRKIDIDKL
                     VELSNIYNVSIDYILCKTDLKENIQLKEEEVNLLDNYRELDTKSKTIVQEQINTLKKL
                     L"
     gene            54748..55071
                     /locus_tag="ACGI5H_000051"
     CDS             54748..55071
                     /locus_tag="ACGI5H_000051"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894776.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9695786.1"
                     /translation="MDEKILELLQKMDTSINDIQGEIKWINTRLDSMDGRFDGIENQL
                     SDLKEGQEEIKKKLDLTYNQVARNMEGITEVGEKIDTLKNDMNFVEMATSKNWNEIAK
                     LKSIK"
     gene            55083..55316
                     /locus_tag="ACGI5H_000052"
     CDS             55083..55316
                     /locus_tag="ACGI5H_000052"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894774.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9695787.1"
                     /translation="MDEKTLELLREIQESIKILNDKLDEFDYTQDKIKSNVEGLLECF
                     SRIDFRIEDLENGQTSLYTKLDIVQNETAKSIK"
     gene            55411..55599
                     /locus_tag="ACGI5H_000053"
     CDS             55411..55599
                     /locus_tag="ACGI5H_000053"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894772.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9695788.1"
                     /translation="MYEQRKAKVIFNKGAGNSRGESYTNRVTIPTTWIKHMDITKLDR
                     EVLLTFDGNKIVIEKIDE"
     gene            55720..56433
                     /locus_tag="ACGI5H_000054"
     CDS             55720..56433
                     /locus_tag="ACGI5H_000054"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="antirestriction protein ArdA"
                     /protein_id="HFG9695789.1"
                     /translation="MLNIYITNLGKYNEGELIGEWAEFPVNEEELEEILDRIGINEEY
                     EEYFITDFETDIEGLEISEHSNIEQLNELAKELEELEEYEIEQLKALLGCGYIDFYDM
                     LEGDICRLSGNYTFIQLDDRSPLDDENLGRSYIEEICCGDLSCIENIAYYFDIEAFSR
                     DLRFDRDMIIENLYEEDIEYYENMTDIEFAENYIERLGDIEELGQETLERYFNYELYG
                     TDLRYENICIASNYLAIVS"
     gene            56501..56641
                     /locus_tag="ACGI5H_000055"
     CDS             56501..56641
                     /locus_tag="ACGI5H_000055"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9695790.1"
                     /translation="MKKLIIKIKSLFKKDLDSSYWSTTESIILKCGNSNQLELLEQAN
                     KL"
     gene            56921..57616
                     /locus_tag="ACGI5H_000056"
     CDS             56921..57616
                     /locus_tag="ACGI5H_000056"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9695791.1"
                     /translation="MNKIIVFYDIEGHPGFQVLVRNVKKYTRQNIIFELVEDYIKNNI
                     GEIDLKDEKIYSSVSWKVWTISDVAIYNTLFDLRLDYNKLIESEEEDTDNKECVKELF
                     CMGKGCKWMETVLLLRQNKIDSSQYNILTINNYTYVKTWAEQCKKILLANNYSKVFKF
                     NEIMKDCDNNLIGDICFKYNNKEYKHKFTFNIKKDKLVNIDCEYKIPFLRYVFNDIEK
                     FLTRYSENISNLK"
     gene            57756..57941
                     /locus_tag="ACGI5H_000057"
     CDS             57756..57941
                     /locus_tag="ACGI5H_000057"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9695792.1"
                     /translation="MQELCSMGLTYPFDFGRGKGKYQTNIDEETIYKRAKENTKIQEY
                     SKKYLNYIAKIKKSISK"
     gene            57975..58271
                     /locus_tag="ACGI5H_000058"
     CDS             57975..58271
                     /locus_tag="ACGI5H_000058"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9695793.1"
                     /translation="MKKIINGYSIYKDGTWCEVIKEGKFIFAGSVNEKLSYEDIYIAL
                     TAKLEFRLHGKLLLSYSLYGTFQGEKQSTLELLAYENNCNINDIEVKQVVENIQ"
     gene            58408..58953
                     /locus_tag="ACGI5H_000059"
     CDS             58408..58953
                     /locus_tag="ACGI5H_000059"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9695794.1"
                     /translation="MKKIANLNKEELKIIWEKNSQLREDVRKACEDNDMYWIDEILCH
                     LNKSLDDWSIGFYNDNYIKIEDNHKFLLELKSVCEKFSFLSEEEQRPLEYAISLIDKL
                     HCMDFENKRFNMLENKINNMVKKLEEKVIEEFNKMTEPLDKEYLLENFIEFYVEAYLN
                     DNEFYIDNEYVLYEKIIKSYA"
     gene            58979..59242
                     /locus_tag="ACGI5H_000060"
     CDS             58979..59242
                     /locus_tag="ACGI5H_000060"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9695795.1"
                     /translation="MLANQIKGIKTSLETSSLRELKGYIKDLRKALSGYKYKNKIDEI
                     TEYQIDKLCYKIDNTDIFDLKYKEIEKYIDSLILILDFIFMEM"
     gene            59280..59864
                     /locus_tag="ACGI5H_000061"
     CDS             59280..59864
                     /locus_tag="ACGI5H_000061"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894760.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9695796.1"
                     /translation="MNEYILISYTKGEGTCDHCGRTIKNIATIKNNVTGEVFHVGLTC
                     VEKIMKLNVTFYKALSREIKKHYKCMEYYSKGLDIETNLNKIVKNNTKYKEGSYAYKS
                     NEQMLEDAIAEVAWSLARMIDSCMRMNKLSKSGLIDIDILNSLFIKYKEYMSKFDENY
                     NKNKYKYKSCYTMKPLKVILDENEDLKELYKSMQ"
     gene            60168..60689
                     /locus_tag="ACGI5H_000062"
     CDS             60168..60689
                     /locus_tag="ACGI5H_000062"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894759.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9695797.1"
                     /translation="MKFKNIVMGMLLGLIIVGVSGVTKVKAAELDNFYIESTDRVIEV
                     LEDESIVLYDTKEQVYNFYPICMGDWNYSFKNKKDLDSAVATYKELSSNINHLSNIYV
                     VNKLNDNGNIKVFLNDGSSIVYIKQDNKYYFYPSCMGDWYLTLDSKIYLTNCINTYIE
                     YYYSLSTGGGTNE"
     gene            60682..60912
                     /locus_tag="ACGI5H_000063"
     CDS             60682..60912
                     /locus_tag="ACGI5H_000063"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9695798.1"
                     /translation="MNNNDKLSILNQLEYIENDIDARNEMIEKFKDLLVKYPKSRDIR
                     RYIKQQTQFLNGIRYIYDNLDILKNMINNDKK"
     gene            61083..61892
                     /locus_tag="ACGI5H_000064"
     CDS             61083..61892
                     /locus_tag="ACGI5H_000064"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894944.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ORF6C domain-containing protein"
                     /protein_id="HFG9695799.1"
                     /translation="MNKLKVKGKQKFMNLEIPVIEGGFGEDKKCMTDKTISEIHNQPN
                     FKIRERIKDNIKRFKEDIDYIDLKVIRDTDDNLELLQTLGYSKMQISKADNIFLLSER
                     GYSKLIKIMDTDLAWEIHDKIMDEYFSMRKKLNDPFENLSPELKVIIKLEQRQAELES
                     GQHELEEKVNVLYDFSTIDYNQQETIRSLVNRMVIQVYQCLNFSAYEDAKLRKRVYFS
                     LWKDYRKKFGVNSYKNTAKKNYDNAIKFIENWEPNYDLSNEIYMFQKVENI"
     gene            62179..62886
                     /locus_tag="ACGI5H_000065"
     CDS             62179..62886
                     /locus_tag="ACGI5H_000065"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427885.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fic family protein"
                     /protein_id="HFG9695800.1"
                     /translation="MIENKFIEKLKYTKNIPNSLYKDLRHNFLFHSNKIEGSTFTSES
                     LQDLIEHNIVKGDHTLDDVITTVNSSYVFETVIDTLGEYLTEKYIKDLHGQLMYNSNI
                     HNMGLSGIYKKIPNRIIGTNSVLAQPFEVEPKMLELIEWYNNLKDITLKDLAEFHYRF
                     EIIHPFQDGNGRIGRFILLKQILENNLKLIIISSDTVDDYRQALKGCHNEYYKPLEQY
                     FESLDDYKEKNKDLWSF"
     gene            complement(63128..63427)
                     /locus_tag="ACGI5H_000066"
     CDS             complement(63128..63427)
                     /locus_tag="ACGI5H_000066"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9695801.1"
                     /translation="MVIKVNFGGNYSPDYIYVPNEISLKKYEIRNEFHIWIDNTEDEH
                     PFWCYENGVQIGLHYRGDAIVYWLNNYILKNANDKARLIESFSNKKLDYDLIINL"
     gene            complement(63623..63805)
                     /locus_tag="ACGI5H_000067"
     CDS             complement(63623..63805)
                     /locus_tag="ACGI5H_000067"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9695802.1"
                     /translation="MLKTLFILLAVFVIIKLSILIFKDALKFLNMFESKNESFIGWLF
                     LCILALVIYNLIDIIL"
     gene            64001..64573
                     /locus_tag="ACGI5H_000068"
     CDS             64001..64573
                     /locus_tag="ACGI5H_000068"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894925.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="integrase"
                     /protein_id="HFG9695803.1"
                     /translation="MTWNDLKNNDITYIVEYINNKLNNSKSLTKVAIGLGVSESSIRK
                     YLTKRGYKRINDEYVFIGDNSMTKVVNNRQQSNNDNTFNMTIEDDNNHNIVIDNQFKN
                     NIVSLAKDYDKIQDVLNWFENKEDTNVIEVVQDGIKIDLHSKDAIRTTVRLNKDAWNL
                     FDEFCGKFREFNKSDLMSMALLEYIKKYDK"
     gene            64706..65632
                     /locus_tag="ACGI5H_000069"
     CDS             64706..65632
                     /locus_tag="ACGI5H_000069"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894927.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9695804.1"
                     /translation="MNYNLKNENVLSELLQNEDEKTRIGILKVYKVLIFWFAKEGKLV
                     EEENDYIVEIVGNDKEEIVRDMSQNKTYNAIMAIIFKINKIFKTLNYDIHFSKPKNLV
                     AEFDLSKYLTQDEVLQVCSKLTNAQDKFIIYAAFCGLIGKDAEDLRGIKIKDIDLEKR
                     LIKLKDTEFKLDKFLFDFTKDTLEQKEYKQYLEQDSNAAEFYLFNSNSEYLIKTKPDA
                     RYGNGLKEMGYSTIRKRLLIINDYLDNKVQLNFTNLKISGIMHQMHLNEKKYTQSGYW
                     TNKSLKEFKEDNNLNFKIQEVLSIYKQKYIKE"
     gene            65637..67205
                     /locus_tag="ACGI5H_000070"
     CDS             65637..67205
                     /locus_tag="ACGI5H_000070"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894929.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9695805.1"
                     /translation="MSKDVKENISNEQKDLNKINLIYHIIYDNDRFKMITRKYFEIFR
                     LKGMSAEEISLKFEEFLYSLISDKFKKINTVNDVKKLRNQENSSSLKLKKRWSDMTLD
                     SLSEDTKSSRKKSSKYLKKELEIVESEYLKNGRIISAGVKNPKELKEQRKDFLDEWKS
                     SSSYNICDYPYLQELSTSKINSAFIHDILMCITEVLKDDYDFDINKIAIKTPPHISPG
                     IFLPFTKGKRYSHLNVKKNENEYMSDDYSAKNLSGKQMNFFYKFSIGQDENIENLKLE
                     LINPDTEKRALPKIYLDKQDLEIIRFVYTYSHMNSFSFYLGDLVKYLGLSDGKKNYIN
                     IKNRLLKLPYYTFYSNQTNDKGELKYEISFNLFSSTTIVNDENNNNRELVKITKSFIE
                     EVERVNTDIMYRNELEKLQLTQSINLAYFLEGRRSFLISCGEDIKNKSFRYDIEDLKF
                     DVHLNKSKTVKQNMEYLELGFNEIKENQFIIKDYKRGNSYFDVYFYEDFEKRKRLINN
                     TILSLPDYMIENKS"
     gene            67679..67945
                     /locus_tag="ACGI5H_000071"
     CDS             67679..67945
                     /locus_tag="ACGI5H_000071"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018112650.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain containing protein"
                     /protein_id="HFG9695806.1"
                     /translation="MSLKYKDKEFVLVEKKNINELDNSNIKYIDLKDKQYYVVTQGKK
                     PKRFNLEDIKNIKKDLDNGISLRKCATKWNCSTRTIQDIKNNIY"
     gene            68021..69199
                     /locus_tag="ACGI5H_000072"
     CDS             68021..69199
                     /locus_tag="ACGI5H_000072"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9695807.1"
                     /translation="MQELKPVARISKSKLKDILDVFKTSIRKVEKIDYSACNSCAIKN
                     NPSFDSHKLNEFCSNCPKLKTISEFSYVTEKETELGTIEIVTNESKCMALSKSAIKQY
                     LAYHFIVSNKNYVRKAVSFQNIADICNVSIVTARHNHNVLLRVGLVYSTEIKRGKFDI
                     VIDEEYKNHLKKEDGGKGYLTMSLDTLNHLLSFENVNELKLEIKKLIWADAKGSKLGK
                     RIRFKKDNLISILPEYIKKSNKRTEAFLRSSKTLFDVSNDTIDTKRYETKETISEKYT
                     EPIRIQISKFFDNTGCSLSSNYSKVLSQINLDRYNLFEEDLRSKLDMEKDIIINDLVG
                     LSVQYGVTRVLAALDYMFNKYTVDEEDINYNEIRNPGAFIRTLIVQSINKNGSLAIAI
                     "
     gene            69808..71568
                     /locus_tag="ACGI5H_000073"
     CDS             69808..71568
                     /locus_tag="ACGI5H_000073"
                     /inference="COORDINATES: protein motif:HMM:NF024930.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RCC1 domain-containing protein"
                     /protein_id="HFG9695808.1"
                     /translation="MDRFEVLKYLKFNVWHSEWPLELLKGAITKDNATGNLLLQLKMC
                     NISDKEIKSAYFTIECFNDAGDLIDNNLKYVYQDINIKPHECLGDDIAIKINDNKTRA
                     INIILEQVVFSDDKVHKYEREEGLIIPKLDKIELLNIELLEELKKDYEEYDFQYEIKY
                     MPNIIEKKAWSCCCGKINKLEKDKCDNCKRSKILQIKKINKNYLESIYKKSLKKKKEI
                     EIKLEKDNRHKLKNINKNNRRTSILLISILLIFIIFIGKNIINKHAFLDEIKYKNEYS
                     KKISVEKDNVYMLKNNGKVTHRKVNGESSSIPGWENIISIASYDNSIIGIKKDGTVVS
                     KGLGNSDSDNISKWRDIIDIECDSGTFIGLKKDGTVVATGNNDYGQCNVNNWFDVVSI
                     EITKSTIEYMKNTTVIGIKKDGKVLLTGYDSLNHRKETDKWRDISKIKCGSYGIFGIK
                     NNGTVVVSGSAYDIKNWKDIVDIHIGLCGIVGIKRDGTIISTDEKFNEIIKNWKDIIS
                     AEIIDNHEGISIVGINSNGDILTSSRGQNLDNIKRLEDVEYINFDDSIDNFLVGIRKD
                     NVIFIRGINNTINEEYNEEI"
     gene            71602..71958
                     /locus_tag="ACGI5H_000074"
     CDS             71602..71958
                     /locus_tag="ACGI5H_000074"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9695809.1"
                     /translation="MKNYIARCLSNMGVLLAGIQVLAGIIIMCQKVEVPYDYLSDTYE
                     QYSPIMIGIGAGVIVSGIVICLVLKGLAELVENSADQTQYQKEILMLLKNNNVNEKIN
                     EVKIEQQFTNEELPKL"
     gene            72167..72880
                     /locus_tag="ACGI5H_000075"
     CDS             72167..72880
                     /locus_tag="ACGI5H_000075"
                     /inference="COORDINATES: protein motif:HMM:NF016296.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LytR/AlgR family response regulator
                     transcription factor"
                     /protein_id="HFG9695810.1"
                     /translation="MIITICENDDMQRDIIYDFVKIFLTKIKVKHYDILMFKNGEELL
                     EEYPNKVDLILMDINLGGRNGFDISKDIRKFDKDARIIFVTVSEKYAIKCYEINAFRY
                     MIKPIYYKEFEKYMLDFAIDWRKREAIITIKRKKQIIKIEEHNILFVEIVNRKLRVVT
                     KNEEHIINDKMDMFEEKLKEDIFFRCHKSYLINLLEVTNFNYNFVYLTSEKIKIKVAP
                     KKTKKLKEKLANFFREIIW"
     gene            complement(73344..73697)
                     /locus_tag="ACGI5H_000076"
     CDS             complement(73344..73697)
                     /locus_tag="ACGI5H_000076"
                     /inference="COORDINATES: protein motif:HMM:NF024252.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HFG9695811.1"
                     /translation="MNENLKELRIKLGLSQKEFAEKLLVSDATISRLEKGERKLTDRF
                     IFQICEVFNVNEDWLRNGNGEMFKNIDDIELAAMMGKTFSSNDEFLKKVFLTFAELTD
                     DEREVIQKVIDKLSK"
     gene            73877..74047
                     /locus_tag="ACGI5H_000077"
     CDS             73877..74047
                     /locus_tag="ACGI5H_000077"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9695812.1"
                     /translation="MYNNNDKKLINLFESFKKIDYTEQSLVYFLSLSFIVNRKCHKDA
                     NLYSRRGECNYE"
     gene            74040..74846
                     /locus_tag="ACGI5H_000078"
     CDS             74040..74846
                     /locus_tag="ACGI5H_000078"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018112641.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phage antirepressor KilAC domain-containing
                     protein"
                     /protein_id="HFG9695813.1"
                     /translation="MNNLNIKGKQKFMDLEIPIIEGGFGEGKKCITDKTISEIHNMEI
                     KHVRELINRNIRRFINAIDFIDLKVVVDNDYNLEVLELLSYRKMQISKANNIYLLSER
                     GYSKLIKIMDTDLAWEIHDKIMDEYFNMREQLIDSYMIQDSIERAKRWIEEEKERLLL
                     KETIQVQQPKVEYHDKVLNPDKLVTTTDIAKDLGMTAQALNKLLHLNRIIYPERINGR
                     IKCWKPYKNYLWLIPEYADFKITEHDTQLKWTEIGRKWLIEFVENIKKIS"
     gene            74910..75134
                     /locus_tag="ACGI5H_000079"
     CDS             74910..75134
                     /locus_tag="ACGI5H_000079"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018112640.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9695814.1"
                     /translation="MIKQILNKRGSLLNLASEYLTEQDYLKFQGWYTHRYSKLDAYDA
                     SINEYLNYKNDKKLITYVFNLKFQEALIEI"
     gene            75158..75694
                     /locus_tag="ACGI5H_000080"
     CDS             75158..75694
                     /locus_tag="ACGI5H_000080"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018112639.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9695815.1"
                     /translation="MNYNYVTKIDLKYGNTQFGFEKYSDALDKYRELKEEFKYVPCII
                     KLHSYVAHQDLYVKEIKADGFEKKYLDIKNLIKLFKEHKQNISDELSLCDKKKEEVLH
                     VIEEMNLDTASLNDKIDTIKELKNTLVKRRLVKYELNKYFAFCNTLYEIEEELKKYES
                     KYKQKENQGKSRFKKNKK"
     gene            75703..75843
                     /locus_tag="ACGI5H_000081"
     CDS             75703..75843
                     /locus_tag="ACGI5H_000081"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018112638.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9695816.1"
                     /translation="MEEYHFNLIKKLCAERKIHKGWFRNIEKCGCGGKCNKKNCKMLE
                     KL"
     gene            75854..76087
                     /locus_tag="ACGI5H_000082"
     CDS             75854..76087
                     /locus_tag="ACGI5H_000082"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009900684.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9695817.1"
                     /translation="MENQIELTEKDIENTLSALNIIKYICIKSKHCKNCPLGYMKNLD
                     EHNCMLYELIDKGLLPCDWSVKKVTRLLDTTEE"
     gene            76106..76519
                     /locus_tag="ACGI5H_000083"
     CDS             76106..76519
                     /locus_tag="ACGI5H_000083"
                     /inference="COORDINATES: protein motif:HMM:NF021182.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YopX family protein"
                     /protein_id="HFG9695818.1"
                     /translation="MELDFRIWNGFRMIHGEELRLLTEEMFIKSGYSEQYYNDICIPR
                     VEDLKIMQYIGLKNCFEKKIFQYDIVKFIFDGVWKVCLVNLSLPKGATVTFESIGGKY
                     TFNLSEIFSKDRKLEIIGNFYENKDVIKKYNLSIE"
     gene            76529..76723
                     /locus_tag="ACGI5H_000084"
     CDS             76529..76723
                     /locus_tag="ACGI5H_000084"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9695819.1"
                     /translation="MDEMIIRVKMGEPLPTLGKIIKCTTCLTNEEKCFKVNKICKLSW
                     INDRNSEGLIVECKGKYIKY"
     gene            76930..77484
                     /locus_tag="ACGI5H_000085"
     CDS             76930..77484
                     /locus_tag="ACGI5H_000085"
                     /EC_number="2.7.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894962.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003950 - NAD+ ADP-ribosyltransferase
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="RNA 2'-phosphotransferase"
                     /protein_id="HFG9695820.1"
                     /translation="MSKKDKLSIFISLILRHKPETIGIKLDDYGYADVNELIEKINNT
                     GRNINIEILEQIVKEDNKQRYSFNDDRSKIRANQGHSINVEVELKELEPPKCLYHGTA
                     TRFLENIKKEGIIRQSRLYVHLSNDIDTAVKVGKRHGVPVVLKINTGKMYENGYKFYL
                     SENNIWLCKYIPFEYVEKISRVVK"
     gene            77511..77837
                     /locus_tag="ACGI5H_000086"
     CDS             77511..77837
                     /locus_tag="ACGI5H_000086"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9695821.1"
                     /translation="MDFNFRKICEKDELTDDFIIKICQLSHEEFGGTIYVPCNIHPCG
                     WDELEVPNPKDLDSDKLMEEFLLEYKFECENISSNIYDSDHPFIGKTLREILMIVDCR
                     FIIGVI"
     gene            77852..78628
                     /locus_tag="ACGI5H_000087"
     CDS             77852..78628
                     /locus_tag="ACGI5H_000087"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894965.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9695822.1"
                     /translation="MENIELTPRDYFEDIKNKKQKNTNENLDIVYENSLILLNKYIVT
                     GQKKGAKKLMFLLECIEKERNVIELGIDTFVYKEDIEKYIDDISKNTVKIIELENYER
                     EIPDEIVEIIEKTKDIFDKMYVLFTDYTGKITKEISKERRDKDPILFGVFSDEKSRAI
                     VDRFYYLGDWEDEYCDLTLEKMINDYKKKGRQDILKHIITPKSLDELKKELDSLEKNN
                     DTYKQVANIKPLPTTKNSSVEPPKLNIFKKIKNRVFKNEK"
     gene            78618..79019
                     /locus_tag="ACGI5H_000088"
     CDS             78618..79019
                     /locus_tag="ACGI5H_000088"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9695823.1"
                     /translation="MKSNVDLTENRDFRDVRGRGINILGIEDAPNRMLSFSDFGIGRL
                     YGKNLEFEFNKNEVFLTGNANDREEKKFLILCEENKVCVRCGDELREGWDKVSIELCN
                     ECYEMLDVEYKNKKIIRELFFRDRDVNIELL"
     gene            79208..79528
                     /locus_tag="ACGI5H_000089"
     CDS             79208..79528
                     /locus_tag="ACGI5H_000089"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894968.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9695824.1"
                     /translation="MFIKSFRCIFRHKFSRIKDCQLITTRSQQYTCKIWMCKYCGQIV
                     AGSTPVYHPNMKVNEYCVKCEFSACANNYEGYCNSKDKEIEFKSICLKGNKEILQCKN
                     FDLE"
     gene            79559..79744
                     /locus_tag="ACGI5H_000090"
     CDS             79559..79744
                     /locus_tag="ACGI5H_000090"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018112635.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9695825.1"
                     /translation="MKINVHVKTNKIGSDCELEFEIDDDDLKDMSDEEREGYIDKIAW
                     DYVFENFIDWNWYEVED"
     gene            79799..80200
                     /locus_tag="ACGI5H_000091"
     CDS             79799..80200
                     /locus_tag="ACGI5H_000091"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018112634.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA ligase"
                     /protein_id="HFG9695826.1"
                     /translation="MKELLEVKKIFDSLASTSSRKEKERILEKYKNNRMFVECLQFLL
                     DSNILTGISKNKICKNLNNTGHNELENIYDMLDYLIKNNTGRNIDVKTIQVFASKDEK
                     LKDFIFNLATKSIKLGITYKTVDKIMPGLII"
     gene            80303..80806
                     /locus_tag="ACGI5H_000092"
     CDS             80303..80806
                     /locus_tag="ACGI5H_000092"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018112633.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9695827.1"
                     /translation="MTDKIIIASVDGEEMIFRTEMKKLEKGDSLIVSVNGVKRLALFI
                     RYISTCEEYIEDIAFQKVDEILYENTIAKEKERVKKVFKDKCMKNYKPIVNTEIDSYL
                     RECGFNCDGRQFFKSIDNTQILISRDCDKDVLTVSKGLTITKTDITNKNLITVIKIIN
                     NSLLIVR"
     gene            80866..83091
                     /locus_tag="ACGI5H_000093"
     CDS             80866..83091
                     /locus_tag="ACGI5H_000093"
                     /EC_number="1.17.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018112632.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008998 - ribonucleoside-triphosphate
                     reductase (thioredoxin) activity [Evidence IEA];
                     GO_process: GO:0006260 - DNA replication [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="anaerobic ribonucleoside triphosphate reductase"
                     /protein_id="HFG9695828.1"
                     /translation="MKNVIKRDGRIVPFDEKKIINAIEKSFLSLRNKGKSEVFDRELA
                     TLIAKKIKNKPCEKMHIEDIQDIIEFSLMASKKKDVAKEYITYREKRNIARGRKTYND
                     YMSIVNTESNDITKENANMNADTPAGMMMKFASEATKTFTDHVLLSEEAKEAMMDNYI
                     HIHDKDYYPTKSLTCIQHPLDKIFNNGFRAGHGSSRPTKRIETSSILGCISLETVQNE
                     MHGGQAIPAFDFYNAPSVRKTFIEEIKNIEIKDDIDLSHLYNIEIEDYIIKDLKELDS
                     EKRNVQHAINRTVWRVHQSMESFIHNMNTIHSRGGNQVVFSSINYGTDTSAEGRCIIR
                     EILKSTYEGVGNGETPIFPIQIWKVKEGVNYNPTDRNYDLYELACKVSAKRFFPNFLN
                     LDATFNKHVKWKMCDPNRYIYEVATMGCRTRVFEDLHGEKTSIGRGNLSFTTLNLVKM
                     ALEAKEKYPNNEANRVAEFIFLLDKYSDVVARQLYDRYLFQCTAKAKQFPLLMSGLWK
                     NSENLNPNDDVSEVLKHGTLGVGFIGLAECLIALIGEHHGESEKAQKLGLEIISLLKS
                     KVEKYKKKYNLNYSVLGTPAEGLSGKFTQKDKKIFGEIKNITDKDYYTNSSHVPVWYN
                     CNVEHKAKIEAPYHELEGGGHIFYVELDGDATHNPKAIMKVVDLMKKYNMGYGSVNHT
                     RSRCMNCGFENADSELKECPKCGSNSINIIQRITGYLVGTTDSWNNAKLAELKDRVTH
                     G"
     gene            83084..83581
                     /gene="nrdG"
                     /locus_tag="ACGI5H_000094"
     CDS             83084..83581
                     /gene="nrdG"
                     /locus_tag="ACGI5H_000094"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894987.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0043365 -
                     [formate-C-acetyltransferase]-activating enzyme activity
                     [Evidence IEA];
                     GO_function: GO:0051539 - 4 iron, 4 sulfur cluster binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="anaerobic ribonucleoside-triphosphate reductase
                     activating protein"
                     /protein_id="HFG9695829.1"
                     /translation="MDKDYIYILDIKHDTIVDGEGFRTSIYCSGCNHMCRGCHNPQSW
                     DIKNGTLTKVLDIYKEIISNKFSDVTFSGGDPLLQLQGFVHLAKLIKKNTNKTIWCYT
                     GFKFEELITDNEKLELLKLIDVLVDGKFEEDKKSLELIFKGSSNQRIIDVQKTLYEKQ
                     IVLYE"
     gene            83616..83747
                     /locus_tag="ACGI5H_000095"
     CDS             83616..83747
                     /locus_tag="ACGI5H_000095"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9695830.1"
                     /translation="MTKEEFITKFLKEQQRRIKVLYYEVENFKMDRRFNERKKSRRH"
     gene            83782..84189
                     /locus_tag="ACGI5H_000096"
     CDS             83782..84189
                     /locus_tag="ACGI5H_000096"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894991.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9695831.1"
                     /translation="MYFETDIIKNKNTVNKIIKYCGGNTEKLKDWLKEIENKSISSLE
                     ELKEYPLKRNYKFVFSKEEAPNLDKLIKMKLRDNCLEKCEICSLENLLSMLNDEILDL
                     NKEDISYEDNIEWIENCKEELIKLKVGSICIDW"
     gene            84210..84527
                     /locus_tag="ACGI5H_000097"
     CDS             84210..84527
                     /locus_tag="ACGI5H_000097"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9695832.1"
                     /translation="MRFWCENCNKYFNAEETLQEYNYFLNEEILICPSCKKDLIPIAR
                     ETELSLGFDSDTNQLTYVEYDSSDYSLLRKVNADVEDVVKPIIHYIRNLNKNSLDLNG
                     ITE"
     gene            84612..84962
                     /gene="tnpA"
                     /locus_tag="ACGI5H_000098"
                     /pseudo
     CDS             84612..84962
                     /gene="tnpA"
                     /locus_tag="ACGI5H_000098"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003378761.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS200/IS605 family transposase"
     gene            84980..86419
                     /locus_tag="ACGI5H_000099"
     CDS             84980..86419
                     /locus_tag="ACGI5H_000099"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-guided endonuclease TnpB family protein"
                     /protein_id="HFG9695833.1"
                     /translation="MSNYILTLQLKTEKFQEDIICNAFDKYRKVYNSCLSELFKRYNH
                     MIESKEHQANCKYKGKDRNKIFSEINKKYNLTEYSLHKFVKFIGKYYKLHSAITQKIA
                     TRCFNAFNKYIYHQAKRVNYIRYNELTSIEGKQNSTGISYKDGIIKFNKMTIPVIIKN
                     NDNYAQRAIQDKIKYCRILKKEIKGKIKWYVQLVLEGIPPKKTTNQGKIKGQIGLGNV
                     GIDIGTQTIAISSKCDVKLLELAPNVNNIDRQIKLIQRKMDRSKRATNLNKFNDNGTI
                     KQGNRDKWIFSNHYLKLKRLRKELYRKQAEIRKQDHYILINKLLNLGNKFYVETMSYK
                     RLQTRVKDTTINEKTGRINKKKRFGKSLANKAPSMFLTMLDNKLKYNNERLYKIDTAK
                     CRASQYNHFSDEYNKKELKDRWNNGMDIQRDCYSAFLIMNVNEDLKSINRELCVKTYD
                     NFKILHDKEINRLKKLKLNGYKLISSMGI"
     gene            86668..86844
                     /locus_tag="ACGI5H_000100"
     CDS             86668..86844
                     /locus_tag="ACGI5H_000100"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9695834.1"
                     /translation="MYDYGMSLSSIMKVILNHQEDIEKLKEEEVAEFIKNKLENEHDC
                     DELKIISEVFNEIY"
     gene            86831..86941
                     /locus_tag="ACGI5H_000101"
     CDS             86831..86941
                     /locus_tag="ACGI5H_000101"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009900666.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyltransferase"
                     /protein_id="HFG9695835.1"
                     /translation="MKYIKHVDNGVMRAIGIDNYKPLLNIIKEKVNLESN"
     gene            86970..87437
                     /locus_tag="ACGI5H_000102"
     CDS             86970..87437
                     /locus_tag="ACGI5H_000102"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009900665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9695836.1"
                     /translation="MGLDLGFYSVKTKVTDLDIYLNKTRGEKYKELNNDEEEFYKFEE
                     LLDIDISLEDWSVIRMIYKAKWEKGYESYEDEAILITKEDLEDYIIPFLKQKDINSKI
                     YNKDKEYYYKNDKKVTVDDRYTQEFWDLVLKEFQKMLNIIDFEKHSLIIMYWY"
     gene            87473..87853
                     /locus_tag="ACGI5H_000103"
     CDS             87473..87853
                     /locus_tag="ACGI5H_000103"
                     /EC_number="3.1.1.29"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009900664.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004045 - aminoacyl-tRNA hydrolase
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="aminoacyl-tRNA hydrolase"
                     /protein_id="HFG9695837.1"
                     /translation="MKKMYIAINSDLNMSPGKVGAQVAHAVYDYLYNKILDTVSCSYE
                     TEIIAHELIDLKCDLTSFKNNGDTICILKAKEAQLLKFKEKGYLTIVDRGLTEIPKNS
                     ITCVNLGIFNEDEIPSTIKRLRLY"
     gene            87869..88024
                     /locus_tag="ACGI5H_000104"
     CDS             87869..88024
                     /locus_tag="ACGI5H_000104"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009900663.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9695838.1"
                     /translation="MYSKGDVVKVWCYQCERIEFQEFVGYFNSYFDNYKLKKRWKCSK
                     CDVINNF"
     gene            88051..88497
                     /locus_tag="ACGI5H_000105"
     CDS             88051..88497
                     /locus_tag="ACGI5H_000105"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895005.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9695839.1"
                     /translation="MKIKKIILGLDNLENVELGIGDVGGFYLDNIHEIIGGFALSYIG
                     KCKKADYLHIQIHKRVDEIQRLHDYKDITNVKIEYEDGSVEDIYVPYKQEGDFLGLDN
                     LYQTSFISKQGYLHIVISKDKTVEEVFNEEFEDDEGVEFSFNMYGI"
     gene            88775..88939
                     /locus_tag="ACGI5H_000106"
     CDS             88775..88939
                     /locus_tag="ACGI5H_000106"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895007.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9695840.1"
                     /translation="MTDKEMEEYIINLIKDKIKEEYGENILPEILMEKFIKLERKGSV
                     TVDVRDLIEG"
     gene            88983..90236
                     /locus_tag="ACGI5H_000107"
     CDS             88983..90236
                     /locus_tag="ACGI5H_000107"
                     /EC_number="6.5.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018112627.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008452 - RNA ligase activity [Evidence
                     IEA];
                     GO_process: GO:0006396 - RNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="RtcB family protein"
                     /protein_id="HFG9695841.1"
                     /translation="MEVQGKYNKAKIFTENVDSITIGQIINLCNQKEFKESSIRIMPD
                     CHAGKGCTIGTTMTISDKVVPNLVGVDIGCGMATIPLEKYINNINYTKLDKIIRDYIP
                     HGFKIHNKSREKLLKNLFNIDINNLRCEVNKNRAYMSLGTLGGGNHFIEVDKSEKGQM
                     YLTVHTGSRNLGKQIADYYQDKAIKYCIEKYKKSYDDAKEFLISTLKKDNKEHLINKY
                     LKDLSDRKLNKPHDDLCYLENDLMEDYLHDMSIAQKYAAANRMVIIADILFKYNSLEV
                     NYDHFIRDIKCDVIECIHNYIDMDSKILRKGAISANKDETVIIPVNMRDGIILGKGKG
                     NSEWNYSAPHGAGRILSRGKAKEKISLDEFEESMKEIFTTCVGQSTLDEAPQAYKPIE
                     DILNNIGDTIEIMEVLKPIYNFKSN"
     gene            90278..91180
                     /locus_tag="ACGI5H_000108"
     CDS             90278..91180
                     /locus_tag="ACGI5H_000108"
                     /inference="COORDINATES: protein motif:HMM:NF013528.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DHH family phosphoesterase"
                     /protein_id="HFG9695842.1"
                     /translation="MIKLITHNDLDGVSCCIIAKYILREQIDVNYCNYKNINDVVLDT
                     LKNHDKYEQILITDISVNEDVAKKLDRIKNKVQLLDHHPTALFLNNYDWANVEIECNK
                     GKTCGTQMLFNYLQRYYDDTSESTLKYFIELVRRYDTWEWKDKYNDLDAKYLNDLMYI
                     MGIEDFIMDMLTKIDSDEMCLFDKLSLKLLEIKQKEIDRYVEKKDENIMVKEILGYNA
                     GIVFAENHISELGNKLSELHPELDFIVIINREIISYRTIKDNINLSEIAKVFGGGGNP
                     KASGSQIDESCIDNYIKDIFNIKS"
     gene            91288..91566
                     /locus_tag="ACGI5H_000109"
     CDS             91288..91566
                     /locus_tag="ACGI5H_000109"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9695843.1"
                     /translation="MMIDKFNYELYNEFPHLSPIIELYNLNIEYIREVVSILINTDMT
                     FQRFKYSKSRVECSMKAYIISPNSKLSVVFAYDCELNGIDLDNLKAII"
     gene            91613..92023
                     /locus_tag="ACGI5H_000110"
     CDS             91613..92023
                     /locus_tag="ACGI5H_000110"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895016.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9695844.1"
                     /translation="MCKFCESIIDNTKDILLTSRSRLLEDNTCEIIAEDNCNNCYDGC
                     YEYFKLNGYKIRGNTYVNVDYYKKIRKIIIAPCSESVHINYCPYCGKQVSKDIKDFNC
                     IPEHIVDVRYKNGDVYDYDMEKSVQEVMDNANNN"
     gene            92054..92227
                     /locus_tag="ACGI5H_000111"
     CDS             92054..92227
                     /locus_tag="ACGI5H_000111"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895018.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9695845.1"
                     /translation="MNLWSKIEEPVMRAVSGIVFNIWGNVCFSIYYIEENKQIELEIY
                     DRPYRYEGKKNSC"
     gene            92337..92480
                     /locus_tag="ACGI5H_000112"
     CDS             92337..92480
                     /locus_tag="ACGI5H_000112"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895022.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9695846.1"
                     /translation="MNKGIKNYITAVNYLLDNLEYMMEDDEFNNEKLQKRIDVIRKFE
                     REL"
     gene            92482..92787
                     /locus_tag="ACGI5H_000113"
     CDS             92482..92787
                     /locus_tag="ACGI5H_000113"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895024.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9695847.1"
                     /translation="MGKIKNGEIDTEDYRLFKNIQKEKDRVYSKYINEEYIMEEFINY
                     LRLEDKDYTTEILERYARYIDENLDNRCPYCVYNICSEHDNCFDGILENLKEKIKIK"
     gene            92945..93145
                     /locus_tag="ACGI5H_000114"
     CDS             92945..93145
                     /locus_tag="ACGI5H_000114"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9695848.1"
                     /translation="MIKERFKAKDSFNMDEFTKIWLMDFKEDFDLSLKKMIENTIKKS
                     IKDTYEETERAITNIENLINKL"
     gene            93350..93634
                     /locus_tag="ACGI5H_000115"
     CDS             93350..93634
                     /locus_tag="ACGI5H_000115"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895026.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF5052 family protein"
                     /protein_id="HFG9695849.1"
                     /translation="MKKFLLTGLLGTMLIAMSGCTGIQSSMKDAESDVSGLNRTVNVY
                     SDNGEVLKTYTSKSMRVKDGDGGTITLDFDGKRVIICNAHVVIEENSSNK"
     gene            93831..93965
                     /locus_tag="ACGI5H_000116"
     CDS             93831..93965
                     /locus_tag="ACGI5H_000116"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895029.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9695850.1"
                     /translation="MILNIATIFNLGCMVANYLQDNTNGILLNGFCLIALLLLNNDLD
                     "
     gene            93992..94144
                     /locus_tag="ACGI5H_000117"
     CDS             93992..94144
                     /locus_tag="ACGI5H_000117"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895031.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9695851.1"
                     /translation="MKITISIEEAMDIIKQHYENKGIEIKDLSFNLEKTGMVRNIKFK
                     GEIILK"
     gene            94355..94777
                     /locus_tag="ACGI5H_000118"
     CDS             94355..94777
                     /locus_tag="ACGI5H_000118"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HFG9695852.1"
                     /translation="MSYPTAIQEFSNQEISIDTVDIRDDSRANIKQDYLKFQPKEKYD
                     VIITNPPFNLSLDIINKALNDVREGGFVIMLLRLNYLGGKVRQRLWGNNMPKYIFVHN
                     RRMSFTDDGKTDSIEYAHFVWQKGYNPKFSQLKVLISQ"
     gene            94803..95015
                     /locus_tag="ACGI5H_000119"
     CDS             94803..95015
                     /locus_tag="ACGI5H_000119"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018112625.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9695853.1"
                     /translation="MEINRRRCEYAARTGRYPNSLILWEGYYSLLNIQYIEDKTRGYI
                     TKFNGMDVIKCNDFLKIELFEKNINN"
     gene            95044..98115
                     /locus_tag="ACGI5H_000120"
     CDS             95044..98115
                     /locus_tag="ACGI5H_000120"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018112624.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003824 - catalytic activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PHP domain-containing protein"
                     /protein_id="HFG9695854.1"
                     /translation="MRYNNYHSHKIYSNIRSLDVITKPQQYIDRAIKLGQNTYFTTEH
                     GYQGNVYEAKTLCDEYKLKMIIGAEFYYVNDINEKDRGNYHLIVIAKNNDGYKQINKA
                     LSLANKNGYYYKPRIDEKILFEIFKPGDVVITTACVAGILKLENREELILKLKNYFKN
                     NFFLEVQSHPHKTQALHNKDVLELSNKYNIDIIHANDSHYIYPEESKYRTKFLKAKGI
                     NYPEEDGFILDYPNSEDIFKRYEKQNVLTKQEVERALKNTLIFDECEEITLINDDIKL
                     PSISKNPNKELKEILNKEWLEKRKNIPKNRWNEYLDAIRYEFDIIEKTHMEDYFIIDY
                     KIVQRAKQEYNGLLTKTGRGSAPSFIITNLLGLTEIDRLNAPVPLFPTRFMSVERILS
                     AKSLPDIDLNAEDAEPFIQSTRDLLGEENCAWMISYKPLQDASAFRLWCKANDMKLSE
                     YDEVAKNLDKYTNDVFWKDVIKESKVFVGVVESVSFSPCSMLIYDRPIDEEVGLLKTK
                     DGVCCNIDGYYCDKYKYLKNDYLTVKVWSLIRKICELANISIPTIEELNILLDAKTYD
                     IYKDKLTCTINQVDSDYATNLASKYKISSVAETSAFVASIRPGFASLLDNFINRESYT
                     TNVKELDILLEDSYHYLMYQESIMKYLIWLGIEESESYDIINKIKKKRFKEKELKELH
                     IKLKNNWIKKVGTENNFEDTWQVVNDAASYSFNASHSLSYAYDSLYCAYLKSHYPLEY
                     YTVAFNLYNEDTERTRKLTDEIEYFSIKLENPKFRFSKSEYFFNRDTNSIYKGIESIK
                     FLNSDIGEYLYSLKDNKYDSFLELLIDLQGHINSKQLSILIKLDFFEEFGKSNKLLET
                     YDIYNSIYSKKQFKRDNLPCDINTMRKYSNKETEKIFKEVDTKELCSYLESQIENTDI
                     PTNEKIQAHFEFVGSCNIKDSNSNPRYCLVIDIDTKYSPKVTLYNISSGNIKIFKVSK
                     PIFEDNKIDVYDLVYLKSIKEKAKSKKVDGKWIRSNTETEWWIQEYWKIEN"
     gene            98218..98469
                     /locus_tag="ACGI5H_000121"
     CDS             98218..98469
                     /locus_tag="ACGI5H_000121"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895043.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9695855.1"
                     /translation="MISILIDEQRYYSLLEEKKDLSMRIDELKEENAFLKQENEEYEE
                     ILNEWECVRKEIVATCKKKEILGEKPSELEMVLQKIEDI"
     gene            98469..98789
                     /locus_tag="ACGI5H_000122"
     CDS             98469..98789
                     /locus_tag="ACGI5H_000122"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895045.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9695856.1"
                     /translation="MSVNKIYEKKEYIIIKSKSGYIVYNTNKEFKEGHTHLKSYNAAK
                     TAIDLVIKRRLPKSYSIYFLTSLMRISNDVQYIKHISDIVYIRNNKGLKEKYINSKNI
                     KKNY"
     gene            98864..99985
                     /locus_tag="ACGI5H_000123"
     CDS             98864..99985
                     /locus_tag="ACGI5H_000123"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018112623.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PcfJ domain-containing protein"
                     /protein_id="HFG9695857.1"
                     /translation="MKSYKEKQFLVFEFEDGKNVKYNLATGEYVGKSGRIVKDVCTQL
                     RGYNLHEVINSFEDENYKCFLNFVDGRVNRSKSSRAWGRRVERIRNIGSFLNEINNYS
                     EYEQLFSAGLKKIIYPIHCDIKSIPKGLISICRNYSITLSDRLIQGYSKNPNLYNNLL
                     SLELNSIRKTNLISILDSGYDRMIFDRLIDIYKYKPQSLINYIDNLMTYEALNGLEST
                     LNELYDYVVMMSVISDKYEKYPRHFLTTHKIASRNYNRLKTQFEEEVFNKRIDKSLEY
                     SYQDYKFIYPKNTNEIKDEAVQQNNCVSSYIQNVIDGKCHILFMRKKDNPSKSLVTIE
                     VRNGKIVQAKGKYNRDVNEREQEAIDKYNNRIERMKKIC"
     gene            99979..100422
                     /locus_tag="ACGI5H_000124"
     CDS             99979..100422
                     /locus_tag="ACGI5H_000124"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018112622.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9695858.1"
                     /translation="MLIEGTKIRLMKEIQGFEMLKIGDIFVITSVGNNGAIHFKTNYG
                     MGFMNYSELKKYFEVAIETKKKEHIWSEWRTATVFGTNKTCTYRTNGKKVEVRMGDFK
                     ASATCHDSDEFELNKGVELCLARIEVKKANKQVNLVLDKINNKEI"
     gene            100432..100587
                     /locus_tag="ACGI5H_000125"
     CDS             100432..100587
                     /locus_tag="ACGI5H_000125"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018112621.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9695859.1"
                     /translation="MSCKFKERCENKNRDCDYCCYNPNAYLEDAFEWNGEGRKPTDEE
                     LDDALEE"
     gene            100631..101191
                     /locus_tag="ACGI5H_000126"
     CDS             100631..101191
                     /locus_tag="ACGI5H_000126"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895050.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9695860.1"
                     /translation="MRWRNILVTSVLVMGSSIHIFANTKEMSTSRMDKNIVADTAKNI
                     NLMYKYEWEQHKNSSEYKLEIKRINLEKDLGIKIEKLIPVTWEVSYYTSLNCENSKYG
                     AITATGEKLQYGFVANNYLKFGTKILVDGNLKVVKDRGSNKYFGNSNAIDVFVPKLEG
                     ESDYKYYKRVNNMGRHYKEGYIIVEG"
     gene            101203..101871
                     /locus_tag="ACGI5H_000127"
     CDS             101203..101871
                     /locus_tag="ACGI5H_000127"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009900647.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9695861.1"
                     /translation="MNVNGIKIPGIIDVSNVYVYGIKESIIASGYPMYEQQVIDMKKI
                     NISEKDLKRANQLGKSKQGSGHDCFSKGIIIQMDLQWSEYMWRQWDRYHHNDYVSSQS
                     KMHRLSKFNLDDMCNKYVDKNTINFLNELIHEYNNFEELKLNNSNNIILRNGEKVEVT
                     KETLWKIIISNCPSGLMLTARVTLNYLQIKSMINQRENHKMEEWRILCDFFKTLPKYK
                     ELMM"
     gene            101917..102810
                     /locus_tag="ACGI5H_000128"
     CDS             101917..102810
                     /locus_tag="ACGI5H_000128"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018112617.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9695862.1"
                     /translation="MAEKRINYNQVFVSGEVLDILNIARMNQGTGQEAIRFTLKVETA
                     PNESVNVDYFTSMFKSDGSPNQMFLGIETIANEIKTRAEDGKGDIVRCVCSLDNNLYY
                     KDGEKKERFQISGTFCNREKYDDKGNPIDDKGEVVKSIKASQVWRVYTLIENIEEKED
                     DLGKYLEIKGLINKYGKQGCNMTFRIHNEDMIEGFKSLYKIGDVGLLEGTVKSMVVSK
                     SAGFGSRIKKSAFTFLEIEGGDEPLKDGDKIFSDKNYPFTDKNIEAMREKIKEKDKKE
                     KQRDIDKNGKTIEIRDDDVPF"
     gene            102850..103407
                     /locus_tag="ACGI5H_000129"
     CDS             102850..103407
                     /locus_tag="ACGI5H_000129"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895053.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ERF family protein"
                     /protein_id="HFG9695863.1"
                     /translation="MEVKEKTMNDGFKKVVNEEIKTYISNLYSDRIDGLKESDSQIEI
                     TKALIAFHLDIESIPKDNTNPFFRSKYANLDTILKAVNPLLAKHDLILMQSAEDAGND
                     KVYIKTKLKHSSGEYIESNSAPFKPAKTNDIQARGALETYLRRYAVQSVLALSFEEDD
                     DGNSLTNKSKGKSEEENSTIKKSRV"
     gene            103468..104019
                     /locus_tag="ACGI5H_000130"
     CDS             103468..104019
                     /locus_tag="ACGI5H_000130"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895054.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9695864.1"
                     /translation="MNCKCRFCKKKLNTNDAYKVEHITSGGNKQNRYYCNEQEYRKEQ
                     QDIYFWKQCQLGIDYIMGYTVINNQKNKMLQEIIKGGYTREELYDCIIEKKDEVIELL
                     NYRKDIEEEYPKLCYVFTILKGSIRDITIKNKQMKYEKENERIYKEVEKSEEYYEIIA
                     PKKVIYNKRQSLFDKVKGVYQDE"
     gene            104060..105586
                     /locus_tag="ACGI5H_000131"
     CDS             104060..105586
                     /locus_tag="ACGI5H_000131"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895055.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DnaB-like helicase C-terminal domain-containing
                     protein"
                     /protein_id="HFG9695865.1"
                     /translation="MVLGTMLKSLTLFSEYKISESDFIIDKVKFFFSLGRIMSKTHNE
                     LDEISVAKFVSSNKLKSEYERYGGWNSLSSAMEYGKETNIAAYIDDLAKNNLLIALDK
                     RGFNVIKEMEHNGLKFIPFEIFQSMKCREVEEFYEGLISSCSVNSIKNNMKVENLLLT
                     KDDREKLKQKTEAGTPYNIIFEYTEKEIGLSNNEESKYIYSLPILSNRTNGIGKGGGI
                     NIIAGFSGIGKTTLLFFNYILAMIYRGEKIVIFANEQKSQYFKSMLVSFIAYNIFNYH
                     DLDRNKIDNGDFTDFEEDLMEKIEKFLRDRCFAENLKFIYMEEFEISEILRKSKELVT
                     HQGFTGIAVDTFKSEDSSDAHYTGKLIENSKLLDSFGNKYNVITMLSMQLLTAQENKS
                     SYLSAGDLSEAKAVKNVCGLLKLMRKVVNELELDSTNKKFFLKPYKLKYNKLKKTTER
                     EYIQFDAKDLQKEYRLLFLNKSRRGQDGDVILLRFYGKTGRLEEIGRCEKVYRGQLSY
                     "
     gene            105596..106657
                     /locus_tag="ACGI5H_000132"
     CDS             105596..106657
                     /locus_tag="ACGI5H_000132"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895056.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003896 - DNA primase activity [Evidence
                     IEA];
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA];
                     GO_process: GO:0006260 - DNA replication [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="CHC2 zinc finger domain-containing protein"
                     /protein_id="HFG9695866.1"
                     /translation="MEIKDLTNEQVINFMEYLGSDLSPKSNDRQLIFNTCLCHNGDSY
                     KLFYYTESKTFHCYSSCGHIGSLIDLLIHINKYEFKDAINEIKDFFGISNQPMLRKGF
                     RIKKKVEQIHDIKDIQIELLPTPKKPYVYKTFQQVPIEEWENENISFEVLKTYQVYYN
                     LYENQIVIPHFCWHDRARPVGIRVRNLDEDKAKSFGKYIPLWYDNRCYNHRLSLNLYG
                     LNVNKKSIKNSKKVIVFEGEKSVLQMATMYKNNPSVAICGSNFSREQKKILIDLGIEE
                     LIIAFDRQFKVKDDEEYVIWRDKIYKLVQDIKDVVNISVIWDKYNLLGYKDSPSDKGK
                     TIFEKLLKNRINIENFVKQ"
     gene            106762..107034
                     /locus_tag="ACGI5H_000133"
     CDS             106762..107034
                     /locus_tag="ACGI5H_000133"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9695867.1"
                     /translation="MIKFLIKNVHMGDKLYCINNIGNYKKGEIYTVSDTSFFGLFHKT
                     KGENCLPIECYFIHLPKKEELESNPKSMTKEEIEDELGYKIKIVSK"
     gene            107055..107906
                     /locus_tag="ACGI5H_000134"
     CDS             107055..107906
                     /locus_tag="ACGI5H_000134"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895059.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9695868.1"
                     /translation="MSIFNKKYGRNVKITEEEPPSPPPKQPIYNRDNIQYDKEMERKL
                     LDIDRLKIELEKEKKIEEERKKVERVKENEGKEWAWVEGYKCTDKNMKCKEFQYELNK
                     AYSMDGDDINIWNWGFHLCLDLGDVFQYYAPNLSNRFFKVKALVKKADKYKYGKEYGE
                     VTLLSGSVLRGHKINKIAAKEIIFLEELTFDKLKLHIQNSFPEVNTKSKWYAICKLGE
                     QEYYHRMFMNQMKKIRFSDTFSQLLFDECRNYCEILEILNKAIAYSKENLSKDMIIYL
                     LMKDIRK"
     gene            107930..108373
                     /locus_tag="ACGI5H_000135"
     CDS             107930..108373
                     /locus_tag="ACGI5H_000135"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895061.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9695869.1"
                     /translation="MDKINKIDLIKLKEMNIYDNYQLKKIASKMILHLRYEIMDFCGC
                     GSPEDISFMIKGVLTAIQNKEKNCNLEYTERCYIFEIEFNNVCGIIGSKNDLIQEFIL
                     NALNSYGLLEHGSSIWGSWLSDYGKQILCAFEIVGDCILDVSYLD"
     gene            108415..109059
                     /locus_tag="ACGI5H_000136"
     CDS             108415..109059
                     /locus_tag="ACGI5H_000136"
                     /EC_number="3.1.-.-"
                     /inference="COORDINATES: protein motif:HMM:NF012376.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042578 - phosphoric ester hydrolase
                     activity [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="metallophosphoesterase family protein"
                     /protein_id="HFG9695870.1"
                     /translation="MSDLHGMYDKFISMLEQINFNSNDHLYILGDVLDRGDKSLEIID
                     YIRKYKNITLLKGNHELMFQESYTDVNSSFLWFYNGGKDTFYDLGMKSYEYKENFYKY
                     IKNLPYLEIIDNFILVHAGLYLPNNYENLSIEQIIELQEEDICVWDRTILNTNKHIKG
                     YTIIIGHTPTQNIKDYEKAEIYKQEGIINIDCGACFDNGKLACLRLDDMKEFYI"
     gene            109070..109597
                     /gene="yyaC"
                     /locus_tag="ACGI5H_000137"
     CDS             109070..109597
                     /gene="yyaC"
                     /locus_tag="ACGI5H_000137"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895063.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="spore protease YyaC"
                     /protein_id="HFG9695871.1"
                     /translation="MDILKISYNNLNAISKISEVLRDIVNEDTLIVCIGSDRVLADSL
                     APMIGSILEKSTIRNKIFGVLGDSIHALNLEQKIQAIKNNYPNSNIIAIDACISKISD
                     KGTIIISNKPVKPGLGVDKKLLEVGDYSIVGIIGRNKYDIYDTSDPELILDLADVISK
                     SLISILLEKEERMIV"
     gene            109594..109848
                     /locus_tag="ACGI5H_000138"
     CDS             109594..109848
                     /locus_tag="ACGI5H_000138"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895065.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9695872.1"
                     /translation="MIQEVRQEILLKNGLILYTGDLVEIKYKSDEDVIEHTCKGKIKE
                     AKELFIKLDTSKKYKTSERMIYSWELKEIKKVDDEDEKDN"
     gene            109832..110089
                     /locus_tag="ACGI5H_000139"
     CDS             109832..110089
                     /locus_tag="ACGI5H_000139"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895067.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9695873.1"
                     /translation="MKKIINSKYRALYLFIFFLIFNLIYSLYFGRNTEIGFYSSTSCI
                     EEYILDIITSIGLFFSMMLAGFDVTENFINSLRDYCEEDAK"
     gene            110079..110309
                     /locus_tag="ACGI5H_000140"
     CDS             110079..110309
                     /locus_tag="ACGI5H_000140"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9695874.1"
                     /translation="MQSEVNKLELKDYISKVELNDMPLTLDNKYMLNEISISEDSKIF
                     AVKDTSGITSYYTEIEFNKLFRGINSILENII"
     gene            110384..111223
                     /locus_tag="ACGI5H_000141"
     CDS             110384..111223
                     /locus_tag="ACGI5H_000141"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018112611.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PD-(D/E)XK nuclease family protein"
                     /protein_id="HFG9695875.1"
                     /translation="MEKELYSFSKLNAFNTCPFQYYLTYVKNLNREQSCYGYYGNELH
                     SLLEQLQQRKITNQEAIQKYNEVIEYANLMDYNFPTPNSRINYLECILHYIENFVPIE
                     CDRYYIEEYFEFDINGITMRGYIDLYYIIGNKIYVIDYKSSSKFSKKDLPKKSMQLIL
                     YAMYLKEKYPDKIIEYVAFDMCKYMNNEKGVLIERNKIDSINDYERAIVKIKYTKELE
                     KQLIDFVVDTVTQIKQLDSNDESVWCKSDDKSNQFFCKTLCSHYNKGCKHKENKSFRK
                     SKS"
     gene            111261..111581
                     /locus_tag="ACGI5H_000142"
     CDS             111261..111581
                     /locus_tag="ACGI5H_000142"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895083.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9695876.1"
                     /translation="MNIPKQVKVGGLFYKIEETEEPILVNNQLCYGLADYGTETIKLS
                     NNLQSERVKEATFLHELFHCIFRDRCIESEDEEYLVDVLSKGLHQVIIDNPNIFELKV
                     SIDG"
     gene            111574..112155
                     /locus_tag="ACGI5H_000143"
     CDS             111574..112155
                     /locus_tag="ACGI5H_000143"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895085.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="guanylate kinase"
                     /protein_id="HFG9695877.1"
                     /translation="MDKLKNIFVFLGYSGSGKDSIVTEISKQFNIPILISHTTRPPRN
                     YLEIINKTYYFVDNKFFKKEKNNFIEMRKYIVHDGSTWLYGIHKSELENKKYALTIVD
                     ASGYKALEKYFTGTKTKLVPFFINADEDTIRKRLIDRGDNLKEIERRLVDDKIKFKEF
                     LNSENYIVIANNLSITNAVEQVKIHMKEGIQWS"
     gene            112146..112640
                     /locus_tag="ACGI5H_000144"
     CDS             112146..112640
                     /locus_tag="ACGI5H_000144"
                     /EC_number="3.1.21.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895087.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004520 - DNA endonuclease activity
                     [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="crossover junction endodeoxyribonuclease RuvC"
                     /protein_id="HFG9695878.1"
                     /translation="MVLALDVSMSSTGWAVINRNKNILKYGKIVTKKDKFKSEDERMC
                     YICNAIQELIITHNIQIVLIEDQFTSRNSKTILSLRKLLGAIMRTVKLNNIEIEYMYP
                     VSIRKYLLNNGKAKKEEVAAYVRENIIDIGEYIDRTCKAKTSDIYDAIALGIAYLNKL
                     DTNR"
     gene            112664..113167
                     /locus_tag="ACGI5H_000145"
     CDS             112664..113167
                     /locus_tag="ACGI5H_000145"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895089.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dUTP diphosphatase"
                     /protein_id="HFG9695879.1"
                     /translation="MSINVKIKKLNQNAIVPSYAKEGDSGIDLYTLKDTVIPAKSAVA
                     ISTGISLEIPYGYEMQVRPRSGISLKGMFFTRYVTIYDKVQPKKQIRKIFVAHPTVRL
                     GTVDSGYRGEIKIITYNEEDFDILIPKHTKLAQGVFQQVPRAILKVVDELTSSERGSN
                     GFGSTGI"
     gene            113332..113505
                     /locus_tag="ACGI5H_000146"
     CDS             113332..113505
                     /locus_tag="ACGI5H_000146"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420092.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9695880.1"
                     /translation="MYRYDDYVNLINDLELPKEIRNKCVRVIMTLENMQDIMVVHKFK
                     TYVVNEKYIEKVA"
     gene            113625..114374
                     /locus_tag="ACGI5H_000147"
     CDS             113625..114374
                     /locus_tag="ACGI5H_000147"
                     /inference="COORDINATES: protein motif:HMM:NF019976.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NERD domain-containing protein"
                     /protein_id="HFG9695881.1"
                     /translation="MFKEIFEKVFMSEEVSKTVKEVNNIIKDTKIQVKGGFGELRLDF
                     ILSRLGKDYIIIKDIIVPGSNKTTQIDSIVISMYGIFVIECKNFSGYIYGNDKDKVWT
                     QIVGKTKNTFYNPVRQNYAHIKAIENIIGNKYNIYSIIVFSDKATLKNVMISGNNIIV
                     INESEILSTISKCKDVTIDKEEIKIIRDKIFDCMKTTNQNTREHVRNLKNITEEDKCP
                     RCQIGHLIKRKGQYGEFWGCSQYPKCKYTRK"
     gene            114663..115775
                     /locus_tag="ACGI5H_000148"
     CDS             114663..115775
                     /locus_tag="ACGI5H_000148"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018112555.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA];
                     GO_process: GO:0015074 - DNA integration [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HFG9695882.1"
                     /translation="MNAFIRKRNKNYVVYLEFRDDESGKRKQKNMGAFDKKRDANKRL
                     AEVKDSIYKDSFLVPNEITLAGFLLDFLEKYKDNISASTYKSYIAICKNHINPSIGKY
                     RLQELRNIHIQNYIDDLAGNLNPQTIKVHINVLRLAIKRAYRIKLIKENIIDGIESPR
                     IKKFKNEIYDKEQMLKLLEVAKGTNLELPISLAIGLGLRLSEVLGLTWDNIDFDENTI
                     TVNKITSRLDGSVILKEPKTESSVRKIFAPIELMNLLKNYRLEQNKKLLRSIVRNEYN
                     LLFFDRKGNPIAEDVMSKKFRKFLENNDLPHIRFHDLRHSHVTLLINSKVPIKVISER
                     VGHSNINTTLNVYSHVLKEMDKEASDRISENLFKAN"
     gene            116012..116146
                     /locus_tag="ACGI5H_000149"
     CDS             116012..116146
                     /locus_tag="ACGI5H_000149"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895104.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9695883.1"
                     /translation="MENLMMSIIAGVIASYIYDKLKCHSERPTKSGWELNIKFHKNKH
                     "
     gene            116352..116729
                     /locus_tag="ACGI5H_000150"
     CDS             116352..116729
                     /locus_tag="ACGI5H_000150"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895106.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0045892 - negative regulation of
                     DNA-templated transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="BlaI/MecI/CopY family transcriptional regulator"
                     /protein_id="HFG9695884.1"
                     /translation="MYLRKLSKSELIVMKFIWNLDTKVKSYQIINYMKEKYSWSEKTT
                     LKTLSKLSNKRFIYVQETSQCTYYTISIKEDKYHEFISQKIHKLLGCNSIKSLLASLF
                     QEELTDEKITSLEEWVKNWEEEE"
     gene            complement(116870..118132)
                     /locus_tag="ACGI5H_000151"
     CDS             complement(116870..118132)
                     /locus_tag="ACGI5H_000151"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895108.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall-binding repeat-containing protein"
                     /protein_id="HFG9695885.1"
                     /translation="MKFKRKVLTLAIIFSIVMSSTLLVSAKELKFRRPAHRIQGANKY
                     ETAGLIADRRKYTQAIIINTDKSLADGLSASGLAGASNSPILLTKQNSIPNSTLKRLD
                     KFKKIYLIGGVNSISKNVENILKNKKIKVIRIEGKDRIDTSYNVAKEISYLKKVDEVY
                     FTNAYQGEADSISISPVAAKYKNPVVLTNGKNIPFKTDGVKTYAIGGTASINDSLVNS
                     TKATRIGGVDRLDTNEKIIKHFYKDELKHPNQICIVSSDNLIDALLSSTIHKEYPVFL
                     VNETNDKSLVTSANFPIIIGDIKNEILDQCLTPDYMLTGNTKRSDISKALDAIYKAKG
                     SKAHEYCYTYNYGNSRYKKAENIDFPHYEFEIISVKNVKQDESSTDGSDTYTDKEDSI
                     KTVGTLIVNSETLEVYEYSFDTQKLTKI"
     gene            118303..119073
                     /locus_tag="ACGI5H_000152"
     CDS             118303..119073
                     /locus_tag="ACGI5H_000152"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895111.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9695886.1"
                     /translation="MSRYSPQTKYFEIAVKFKKVNTFLFWVFFILSIIFTFQNNNNLI
                     TCFSIISLIILNMLDIFICNYQEKGESKRRNDFIDNSFDCKYSTHNSIEYYDNDEIHY
                     GLYKALVNVYQNAFFSKEILSYTRKFIIIKNVIPCMIIVIFSFIGFSNSNFALPILQL
                     FFSKYFILDLINTSGYLKNVESVFDSITDMFETGLVAKKDNKVESKIIKVLINYETNI
                     SSSKIFLNSKVYKKMNPELTGEWDKIKKRYNIKEVSNI"
     gene            119070..119882
                     /locus_tag="ACGI5H_000153"
     CDS             119070..119882
                     /locus_tag="ACGI5H_000153"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895113.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016779 - nucleotidyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotidyltransferase domain-containing
                     protein"
                     /protein_id="HFG9695887.1"
                     /translation="MSVNSYLENLSHELIIRDNEKENIKKSIEVIKSRLKSYFGNNIV
                     ETFCFGSYTRGTMLPRKVNENSDVDYMVVFSNSFLYAPQTLLNKLRDFVRTYYSKSEI
                     YQSNPTIVLELNHIKFELVPAYSNNMYLWQENHYRIPAKASNYNDWIDTCPDDINSRL
                     TRLNVESNNKLKPAIRIIKYWNSLNNNVYSSYELESAILENMHCYWRTSIQDYFTAIT
                     ESLIYNFGTPSWKVDKISSLKKWYNHALKEEYIWRNYIQSNLYMENILPSIK"
     gene            complement(120026..120961)
                     /locus_tag="ACGI5H_000154"
     CDS             complement(120026..120961)
                     /locus_tag="ACGI5H_000154"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895114.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HFG9695888.1"
                     /translation="MAKQRSKRISINGELNPENIKLWKQYKRAKQIAGKSEKTIYNYE
                     CDIMQFFKFLNIECFDALLTDINEEEIEAYIGYCMEHGNNEKRIRRRISSISSLLSFL
                     KKKRKITDNWCEMIERPGTGEEVQKRTFLTEEQLSKLKEKLSEQDNLQLEVYINLGLA
                     TMARSNEISQFRWDNIDLDNRWIHGITAKGGVSRDFRFSEEVQHLLIEWKDYLSQNNI
                     DYPYIFFTRYGGKYNQVNSNVLSSWVKKAFRLIGIEGGYNHDLRHSMSNLLKDRGVPI
                     TTVSKLLGHSGVDVTINHYTIENKNKLAEEYDKFM"
     gene            complement(120996..121307)
                     /locus_tag="ACGI5H_000155"
     CDS             complement(120996..121307)
                     /locus_tag="ACGI5H_000155"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895115.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9695889.1"
                     /translation="MLSKEMIELLSQYGYTAILLTVVMLWFGRYLEKNRQLEQDDRKK
                     ERAYFSREIKEQRTLFGNTIDKFDDKLDKFAEALNTNNSRLERVETDITKIKDKLETR
                     D"
     gene            complement(121308..121559)
                     /locus_tag="ACGI5H_000156"
     CDS             complement(121308..121559)
                     /locus_tag="ACGI5H_000156"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895116.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phage holin family protein"
                     /protein_id="HFG9695890.1"
                     /translation="MDIMQFIPENLIMLIGGLYILGTFIKESNIKNKYIPFILLVIAM
                     ISSCLFMKELSIEAVFEGILCWGASIGINQIQVQNRKEK"
     gene            complement(121571..122188)
                     /locus_tag="ACGI5H_000157"
     CDS             complement(121571..122188)
                     /locus_tag="ACGI5H_000157"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018112549.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucosaminidase domain-containing protein"
                     /protein_id="HFG9695891.1"
                     /translation="MNILDKSTATLEQVFSYLDTLKNNSNPPHFLCRAIVPIIYKEAE
                     KKGVNPVIAIAQAFVETGYFNFGRVLNPSYCNVCGLKGNKGGGDLDPTAHTRFNCWED
                     GVSAFIDHLALYAGAKGYPKYSELVGKVEYKVNGTTLDPRHFPYLHGEAKTVESLSGK
                     WCPDMNYGQNIINICNKISSMKVENNDVKLEQIKTKVKELNEILG"
     gene            complement(122200..123015)
                     /locus_tag="ACGI5H_000158"
     CDS             complement(122200..123015)
                     /locus_tag="ACGI5H_000158"
                     /EC_number="3.5.1.28"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895119.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008745 - N-acetylmuramoyl-L-alanine
                     amidase activity [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase"
                     /protein_id="HFG9695892.1"
                     /translation="MNIKTLTVHAGHNPDGKVGSGAVGNIKESTEARNVLKELIPLSQ
                     KECKVYDCTCNNGTSQSDILNKIIDKCNSYNTDLNVSIHFNSGGGRGVEVLVYNLNDK
                     ETVEIASRICKKITETYHAKGDKDFKNRGVKEKKTLAFLRRTKAKSILVECCFVDTSD
                     TKKYNAKDMAIDIYEGIFNKSVAGKPQDNKVKYAIVYEGEVDKVIAQLMAMNYKTNEV
                     SVCDLENYVPGHCENLYVIGGASSKIKTSERFTKLQGDDRWATLHKVLDFIGK"
     gene            complement(123130..123267)
                     /locus_tag="ACGI5H_000159"
     CDS             complement(123130..123267)
                     /locus_tag="ACGI5H_000159"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895121.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="XkdX family protein"
                     /protein_id="HFG9695893.1"
                     /translation="MNWYKIITDFYNNGNWTKEQVKTAVEKNKITASEYKEITGEDYI
                     V"
     gene            complement(123269..123568)
                     /locus_tag="ACGI5H_000160"
     CDS             complement(123269..123568)
                     /locus_tag="ACGI5H_000160"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898419.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9695894.1"
                     /translation="MIYLGNFMETDEQNIKYIGMIHYKPTLLSEEELKNGILIEKLPV
                     QQYVENKEAKLFINIDTKEVFYRYTDIKSSIEDKVNSTEQTIADLTFQLMSNGVI"
     gene            complement(123565..>123939)
                     /locus_tag="ACGI5H_000161"
     CDS             complement(123565..>123939)
                     /locus_tag="ACGI5H_000161"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895124.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9695895.1"
                     /translation="IKFLNDFVFVSDSGRSIEVESGKKSGLAKYDANLNLITYGGSDR
                     YENFEIYNGYIYTFNSLSSSPFIKINLNTLKEVNSYRTLINTNPQKGMFIINNIIFFI
                     GGGIHRNILSKKVYSDEKGEEL"
BASE COUNT        46015 a        15980 c        16522 g        45422 t
ORIGIN      
        1 atcccaagca ccaccaacga gccttatatc agtagctcca ccaccataca tagaataata
       61 agtacccata acctgttgat ttaaataacc tttgccacca ccattaaaac cacttttagt
      121 gttattagct gtagatgaag aagcataacc actttcgccg acataaatat ataatgtagt
      181 ttgttttttt aatgtaattt cacctttaga atatccgcct ttagcatcag tatgccaaga
      241 agaattgttg atacctccag aagaacccca gcattcaaat ttatatttgc caggtttcaa
      301 tataacactt tgtggcgaac cattgtaccc aaagttccat tctgtctgca ttttctcact
      361 ctcctttaac aataagttat caattcattt acacttgttg caatgttaga taacccacca
      421 cttaattttt cttctatatt aaccaatcta tcttcgattt tcttagatga ataagtagtc
      481 atttcagata ctctgttatc atctacagtt gcattaataa aatgagtttc tgcatttcca
      541 ttaataacat aaacatttaa ctcaactttt acttcacttc taatctcaat tgaattatca
      601 tcaactattt taaaatttgg aactacattt tcttttgtag tagcatctat aatatttaca
      661 actattctct gtgttaataa actatgtgtt acagttgctt tgaatccatt ttctgcatcc
      721 tccacccaat catcaatagt tattgtttga gtagatgcaa catttgaacc acccgctata
      781 agctggtcaa tcttagtatt caactctgtt ttagcagttt ctatatttgt attaactttt
      841 tctatttctg tattagtgtt attaggtaca ttctttattt tttttactac ctcttcattt
      901 aacaatttat caccttcttt tttatttaga gagctacatt agtaactctc tattttgaac
      961 ataaaaaaag aactcttaca gttctatgat aatgaaatct ctagtgcttc acacattttt
     1021 cttacttctt ctcgatattt aacaggtact tggtcaattg tttttaaacc tctctctatc
     1081 aatcctacat aaattgctgc catactactt cctccttcat ttaattttat attttttaat
     1141 gacatagtag atgcctgttg actacttaat accatttcac atatttcagc agtcgctaac
     1201 attaaatctg ttatgtcatt atcttgcgtt ttttgacttg aatctaaatc atctaattct
     1261 tttctttgtc ttgacttctc aattttttct ttatctattt ttatcattta atcacctctt
     1321 aaagtgtttc aacatctaaa ttgaataaca tagatggttt ttttatagtt gtattagtgt
     1381 ttccttcttc tactattact ttaggttgtg cagattgtat attcatatct tttaactcat
     1441 atatctcctt atatccattc ttagtttttc ttgtctctac tttaaccata tctttaaatg
     1501 tatctgattc atttatcttt aattgtactt ttaatttatt tactaaatga taaattggat
     1561 tgttagaatt taaatcttct aacagacctt tattgagtgt aagtactaca tcttgtgaat
     1621 tatcaactat actagataca ttataagtat tcccattgat taatacagtt gaatctttta
     1681 ctatagttgc tcctgcttct tttttataaa tataaacatt tatatataaa ttatttccaa
     1741 tgtcagaatg tgctttaaat acaatcttat tttctccaag aactaaatcc tctggattaa
     1801 tctcaaacgt aactgttcct gtagataagt cttctattat acttgaacta atattattta
     1861 taaacatctc tatttttgtc aattcattat ttggattttg caaatctatt tcaatagatg
     1921 agtatgactt attctttatt tccaaacaag ttttctctga atctactttt gagattatat
     1981 ataatgtttc atcttttatt aaagcatcca ctatatcatt aacatctctt ggaatatata
     2041 tttgtgagaa agtatataac atagaaccaa tctctacatc tttaatttta tatgtttcct
     2101 tatttatccc tgtaacatac aaagtcttat cattttttat aacaaatata tgtttatcat
     2161 cataagattt tatatatttt acattttcta atactttagt aaataattta ataattgtat
     2221 tttttgtatt ctcattcagt cctaagattc catttatatt atatccttgt acgtataatt
     2281 gaccttctgt agttatagcc aatatataat tactataagc atatatctcc cttatattag
     2341 aaatagttaa tacttcttgt aactcattaa cctcatcatt atgccctatt ccaagttgat
     2401 attctgagtt tttaccaata gaaaacaatg agccatcatt ttttaagaag taagtaaaat
     2461 tatcaccaca agcaacatct attatatttg ttaagttaat ttttataaat tcagaagttg
     2521 ttgttagctc agatttattt atagcaagtt ccccaaattg atttgaacca caaccataga
     2581 catccccatt ttctaatatc aaaattgaat gagttgatga taaagacatc ttttttatat
     2641 tatcaaaagg caatgaagtt gaataatttc cagcatttgt gccaaatggt attctataat
     2701 taatactatc atcattatgt aaaaatatct tcttatttac taatagtcca taattatttc
     2761 ttataataga catttcatta gaaaaactta aatcactagg attatcacta gaagtgtttg
     2821 caatctgatt ttcttcatgt ccattaaaaa tacctacttg accaactaca gcattacctt
     2881 ttccttctaa tttattatta gtatattgaa ctataagacc attatgctgt gtatatacct
     2941 gttttacatt aaggcaattt ctaacaggtg ttttttgtac aacatcagaa taattattga
     3001 tttgacccaa ttgtctacta ccaaacacat ataaggcatt atcattatct atataataag
     3061 catttttacc atttgcatat atgtgcttta tattacttgt taattttttt aatactacag
     3121 taccagattc attaaaacct ataccatcat cagcatttcc tccagaatat aaatctccat
     3181 tttcaagtaa aacaaaaata gtgtattctc ctagagcaac ctcttttata ttactattaa
     3241 acgctaaatc cttatatcct tcaatatatc ctgatgaatt attatatgaa gtaccaacac
     3301 ctaaacctcc taatgagtta tatcctgtga caaatattct atttttcatt gtaattatag
     3361 ttttgccttc ttccaacatt aaatttgata tagttgatgg gtctgttaat ccttcaatat
     3421 ttattttagt taaactgttt gaatttgtat ttgaacttat gtaatttcta tttccacaac
     3481 ccattaaaga aattatatta tcattctcca ataatataat aaaaacatac cttccacaaa
     3541 atatatcctt tattgttcca gaaatattta ctttagtaaa agtatttcta ttaatatcat
     3601 cccctaatcc taattgacca tagccatttg aaccagttga aaataattca ttgtcatagg
     3661 ttagaatgta agaagatttg taacatgtta ttactttttt tacattatca ataggcacct
     3721 tagtaaaagt acccctatca atattatctc ctaaacctaa ttgccctaag tcatttgttc
     3781 caattgaata gacttgatta ttatttgtaa gaataaataa acaatcattc gatggaataa
     3841 attcttttat attatctata ggaactttta taaattcaga ccgagcttta attgtcccta
     3901 acttgttacc agcattatta ccacagacat atccttcgct attatttaat aatatatata
     3961 aagcttgtct atcactttta atttctttta tatttgatat gatatatttt ttagaaaatt
     4021 gttttgatat atttacaaaa ccatcatgtc taacatcata aggttttttt atgccaaaac
     4081 agccatgaga atttactcca gaacaatata tgttcccaaa ataatcttta attactatcc
     4141 ttaatccact agcatatatt acttgtgaat tatatgcaaa aaaagcattt gataatgtgt
     4201 atttttgact attagaataa taactactgt ctcctctttg cccacctgca tttctacctc
     4261 ttatttcaaa tttagactcc atccttgttt tacttgttgt atataaaaga ttgtctgttc
     4321 caagataatg attataataa ggcatagaag acgatataag acttcttaaa cctaaattct
     4381 tgtcttggga tgaagctcca aaagtcgaag gtcttcctgt gaattttatt tctttatatc
     4441 ctccatcact agcatctaat aataaacata aattatagtt agaaaccaga acttttgata
     4501 atttaggttc atctattaaa actgcgactt catttgcatt tgagttttta cttcctacaa
     4561 actctccaaa ccttgaataa taatcatcag ttacagaaat tttaatactt gtgctataat
     4621 aattatgtct cccagaaaca tagtagttat tagacgtagt tctaattaaa catccattat
     4681 taaaaggaat aatttcagca atgttagata catctgatac tgttgtatct gttttatatc
     4741 ttgaatatct catcttaaca aaaacgctcc tacttgaggt atcattaaga cttaattcgc
     4801 caaaaacatt atatcctgct gcataagata ttctgctatt gtctatgcaa tatgaagaat
     4861 ttgaatatgc aataatttca tttacataag ttacagtact tactttagta aaaatatttc
     4921 tattagtagt gtcattaagt cctaactgcc cataattgtt taaaccagtt gaaaataatt
     4981 cattagtagt tgtttttaat aacgcatggt tatctcctac agaaattttg tcaacagaag
     5041 aaatatttac tttagtaaaa gtatttctat taatattatc ccctaatcct aacactccaa
     5101 atacattata tcctgttgaa tataatgtat tatcacttag taatataaac gtgaaatatg
     5161 agcctagatt taaatatata tcttttatag taactccttc ttctaattcc aatggcactc
     5221 tagtaaactc ataacaatga cgattatgac ctaaacctaa acctccataa gcgttgtatc
     5281 ctgctgcgta tagttcatta ccattcacaa caataaatgt agaggtgtca tttgctttca
     5341 ctaaagagat attcacaaaa ttattttcaa gccctatatc taaaactctt tcatcatttt
     5401 tatttattaa taatctatta tcaatagact caatatgatt acattcttca atatcaaagt
     5461 cctcaaattt ttcaaatcca tatataaatt tatcatatct ttttaaataa gaaaaactat
     5521 aattgttatt tcctgtcata tacaattcat tgttgctagt taatataaag cttatagcat
     5581 aagcacattt aattttactt atatttttaa tactaataga agattttcta ggagtatatg
     5641 ttgatgtatc acaatttatt ttatctccta aacgcccatc tgggttggct ccagttacat
     5701 atatatcatt attattagct atataaaatt tatgatatct accactttct atatttttta
     5761 cattagatat agatagtttt gttaagactg ttactgtagc tcctccacca acaccaactt
     5821 gcccacttga attatctcca caaccataga catctccatt ttctaaaaga aaatttacag
     5881 caccttgagc agtagaaatc tttattacat tatctaaatt tactttagta aaaatatttc
     5941 tattagtagt gtcattaagt cctaactgcc cataggaatt tgtacctgtt gaatagactt
     6001 cattatttaa agttaatata tatgaacaac tgactcctgc aaatatttct ttaacactca
     6061 aattatcaat tttagtaaat gtatttacag tagatgtatt tcctaagcct atccctccaa
     6121 atttattatt accacataca taaagctcgt tgtcatttgt aactaacata gaatagccat
     6181 tcccacaagc aatttgtttt acattactta tatttatctt agtaaaagta tttctatcaa
     6241 tattatctcc caaacctaac tccccatctg tgtttaagcc agtagaatac acatctccgt
     6301 tatttttaag taaaagagaa tgagttccag aagatgaaac atacttaaca ttgtcaatat
     6361 ctatttttga aaaatatctt ataggtgata ctttatttcc aagtcctaaa ttgccaaaaa
     6421 cattatatcc tgctgcatat aactttaaat catccttaat tataaacaca gaaccagaat
     6481 ccatatctgt aaatatatct ttaacattaa aagtatcaaa atttttatta aactcttcta
     6541 ttttaaattc tttgtttcca aataaagaac ctctttgtaa tagtttattc tttttcatat
     6601 aattccccct atctcacttc gtaggaatac ttgtttattt ttatttcagt atcacctttt
     6661 tgataagatt cttctgtttt agtttcacta tagttgcttc ctaaatcatg aatatatctt
     6721 attttgttgc ataaaaaagg aactgttaca tttttaaata atacagttcc actatttgaa
     6781 agtaactcta attgttgctt aaatttatta agctttaaac catctaaatt acttatgttt
     6841 ttagaatcat atagggtatc ataccaatac ccagcttcat ctgctgtagc ttccttatct
     6901 aattctaatt caaatagaat tttaagtatt tccacagaca ttttattata attttctttt
     6961 aatattttca attgctcgtt tgtatttcca ccagattcaa gaactttaac actagcatct
     7021 aattcattta ccgcatctga tatattttta gatactgtac ttaattcact cgaaccaact
     7081 ttactttgta ttagatttat cttatctaaa ttagtagcta tattactttt attttcattt
     7141 atcttagtta gactctcatc aaattttgca ttaattttaa tactagagta agtactatct
     7201 agtgttgtta tattatcatt tattgtattt ggtataacct ctttatttgt attcccattt
     7261 acaaccgtta ctcttacatt tatagctagt tcattgaata tctctattgt attagaatct
     7321 actatagtat aagaattagt catacttttc ttggttgctt catctaatat tgctacaaat
     7381 atattttctg taactaaatt atgattaact ataagtttaa aatattctcc atcagcaatc
     7441 caattcgatt caacataaga tttactaaat gctacattag ttgcagcaga cgtcatctca
     7501 gctattttct cattaacttt atcaaaatca tatgttaatc tatcttttaa agtatccttt
     7561 acagttccat caacactttc tctagcttgt attaattcgc ctctagcatc aagactttct
     7621 aattcttcaa acctattttc aaattcagtt attttattac taacagtagt tgtcatatca
     7681 gttttagcag tatttacttc aactattttg tcatctactt cttttatctt tgtatctaat
     7741 tttatagtac tttcatcaat acaatcttcc acatcagata tagcttgatt tacttcatca
     7801 agtttgtaat caatttgctc ttggttatct gtaagtttat cttcaaatgt cttatcatac
     7861 aaatcaaaag tactattagc tctagtatct aagtcctgaa acttcttatc tgtctgaact
     7921 tgaacatcaa gcattttatc atcaactata ttatctattt cttcagactt agcatctata
     7981 atctcgtcta attggagttg gcaatctgta agtttatcat cgacttgaat ttgcatattt
     8041 tgaatggatt cttcacgatt tgcctcttga ttttgacgtg ttaactcatt aaactctctt
     8101 tcttcttctt gtatgtttct tatatcttca ttataaatcc taatctgctc tgctttatct
     8161 ctaacttctt catttccaag tatagttatt tcaagttgtt caactctttt agttagctct
     8221 ttattattct ttataatttc ttctgcttga gatattaaga ctaataaaac tccatattca
     8281 tctgtactgg tcaaatcatc atcattaatc ataccttctt caacacgata ataaagatta
     8341 gtagtattaa taagagtatt tccttttact agagaaagtt ggaatgtatt tataccaaca
     8401 cttgcaagtg cttgtcggct aagttctatc tctacaacac cactagtagc atctacaact
     8461 tcacattcgc cattaacttt ttgtccgtct gattttgtaa tgctaactaa aaccctgtca
     8521 tattcagata aatctattat ttcatctttg tttttcaata ttgcttcaat ataagctgtt
     8581 ttgacatcat tttcattata aataaaataa tctagtaatc ttttgtttat tctataatta
     8641 ctaaagtcga cctctatggt atgattcttt atttcataat ttttcaaagt atcacatcct
     8701 attgttcttt attttgttta gtttctactt tttcttttct taactcattt atctcttctt
     8761 gtaattgtcc atttagtgcc ttataaagta ttaattcatt ttgcaatcct cttatttctt
     8821 ctaaagctat tgtatatgct ctttgcatgt ttacttccat aattattatc ctcctttata
     8881 tatccaaaga atctttaaat ttttctatgt tttcttttaa atagttatat cctgattcaa
     8941 gtgggttttt acctgttgca tctagtgtat taattccaaa atagttatca aaattatctt
     9001 ctaaaataga tatattttca tattcaacag catctaaacc ttctcttctt gcttcctctg
     9061 aaatatatcc tgatacttta atctgagcca ttttattact ataggatata tttacagttg
     9121 atatcctcca ataataaact tgttgacctg ttgctaataa cttactcttt ccaatcgcca
     9181 tgttgttctt caccacccat tattttgtaa tatgtatgtt cgtatcctat tcttttacct
     9241 attattctaa aatcacattt acctgcatat ccaactactt taaaataatc ctcacctttt
     9301 tcaacaacct tgcaattagc attagaacta aatactgcaa aatttaatat actctgagca
     9361 aagatattat ttaattttat tattgtacca gtttcttcaa cttctacatc aaataaaacg
     9421 tcttcaatta gaaatttagg actatcaact ggagacatac caaatttcgt accatttatt
     9481 tctatacttc ctccgacttt tgaaccattt ctaccaaaat tgtgacattc atctcctcta
     9541 atcatgaaag atattgctcc atcactccaa ataacaatac cattgtcagc cctttcgtca
     9601 gcagatgtat aaaacctaaa atgtccacgt gaaaagtcca ttcttgtgtt tccatcagaa
     9661 ccaacctcta ttttattagc tcccaatttt gcttcattta aatcaaattt ataattctca
     9721 tacgcatcta catatatagc agcacctcca tctccaacaa aaaaataatt attactatta
     9781 tattttaatc ttatagctga tgcttgacta gaaccatcag accttcttgc atctattgca
     9841 aatccagacc tgctacttcc aaataatctg attattggtt catggccagg tggagtagtt
     9901 aatatatcac atgctatagc tccttgattt actgttaaac cactcctgct tatctctaca
     9961 taatttgata tatcattaaa tccaaattca attttatcag gtttaattcc tacaattgaa
    10021 cctaagccat ttcttgtaac catcattgtt atatcgtctt tggttaattt aatttcagca
    10081 gcattagttt tagtcacacc atctactcta gctacttcta attttatttc tttagctgta
    10141 gcatttattt gagaaaattc ttctgatata cttccaccca tacctgttat ataaattcta
    10201 tccactgtat ttttaagttc atttatcttt aagttatatt gagcatttgc atttatagct
    10261 aaaattctgt ctgaaggtgt aattatacta tctgaaataa ctgaattgat tatagagttt
    10321 agattggtac ttgctgcatc caatgctgtt tttgaagtgt ttattgctac taagtctact
    10381 ccagtagttc tatcaataag tttttgtagc tctgtatata aacttgcttt gtctgtatct
    10441 aataaattaa gttcaatatc aatcttttct ttttcttcat ctgtaatctc attatcatta
    10501 aaataattag acatattaga actaaatgta cctaaatctg catttaactt aattatagac
    10561 ttatttatgt tttctcttaa tgttatattt tcttgtgaac caccaaaatt tttagtaact
    10621 tcttttacta atatatttac attttcagct ctctggtcta taagagacat attttctttt
    10681 atatgagatg catcttcttg tacctctaaa actgtctgat gtatcccatc tatgtctttt
    10741 tcaataacta caaatttttc attgtgtttt tcatctgttt catacaatgc ccagatttgt
    10801 tcttcagtat tttttcttga attaccatca aaagatatat tgaatattga tgagtttata
    10861 ggaacttctg tatgctttcc attgtcattt acaactacta aaaattgtgt gtttccctct
    10921 ggtaatctta cattagaaac ttttaatgtc cctggattat cagcatccca gtatatatat
    10981 tttttatttg tctctttatc tactacttga taaagtgtgt tgttataagt aacaattact
    11041 ccagtaattc taatccatga atctgctggt gaattatcca atatcaattt acatcagctc
    11101 cttttgtata tttttcctag gaatatattc atctggtagg ttaattcttt tcttctgttg
    11161 ctgaataaat aaatgtcttt tagagttcaa tgttcttgtt gcatgttcag ctttagtcaa
    11221 ataatcagct atagttcttt tgtcatcttc ttttattttt ttattactta aagttaattc
    11281 taaagtatcc aatttcccat tttttaaatt ctgggtaaaa gatgtaaaat atactaattc
    11341 ttcttcttta gattctttgc tatgtaacac tataatatct cctaaactca aatctccctt
    11401 ccaatgttgt ctaaaattaa tatctataat tctatctaag aagtttataa catccagagt
    11461 ccattctcgt gttggaatac atttcaaact taattgcctt ttaccttctg ctattaaatc
    11521 ttcaactttt aaaaaagcat catttgtata agtgtcatag tagaggaact catttaattc
    11581 atctaataga acctcattaa atattaaata tccatcctca tcagttgaag tctccctctt
    11641 acaaagaata tttatatctt ttatactttc atctaactta gctatttctt cttctaaatg
    11701 ttttatttga acatccaata tgactttttt atcttctagt tcacttatct ctactgctat
    11761 tttagctgaa tttatttcat ctttatgctg tggattatca tatgtctttt ttatatcttt
    11821 tttcttactt atcatctcta ttaccatttg ccattcgttg cttttactat cacgttctct
    11881 ttgtttctta agctttgtat ctattagttc tctccaaatt ggctctctta tttcattcat
    11941 ttcttggtat ttctttatag ctctactaag ttcttcactc atttctttat tgtctaagaa
    12001 ataagaataa ttctcaatgt aatcatatcc tgtaactgta gctcctatta cattcatatc
    12061 ttcactacct tcaagcttca gtctagttac tatatcatca ctatttgtag ttctttcaag
    12121 tgattttatg tagttatcat gagataaata taactgaatg ttatctccaa aactatctat
    12181 atgatacaaa ttaactaaat tattataagt atcaaaatca gctatacatt caaattgttc
    12241 ttttagttca ttattaaaat agtctaacca gttagaatta atactttctt gccatcttac
    12301 cttttctctc ttattacctt cactatcagt ttcataagca attgaatcat ccacataacc
    12361 aagtttccag cctgtctctt gttttaaata atcattaaga gatataatag atgcttcttc
    12421 atctttggta aacatctgta atccatagtc ctcaatattc acatcaattt ttcctagttt
    12481 aacttcttta gatttagctg ttactacttt taacttatca tctgttgtta caacattctt
    12541 aattacaaag tactctttat tattaagaca aataagacgt tcttctttta cttcttcaaa
    12601 aatgggattt attattttat taaataaaaa tctatctgta atatattttg gaatggtcag
    12661 ttgtatttca tctactccac caagttcacg ctttatagaa tttaaaaagt tgattgggat
    12721 ttgacctaaa aatgacttgt tcatcttgtg aatggttaat gtgtaatcag attttatctg
    12781 tttaagattc acattaaaat gcatatttta tcaccttctt tacataaaaa taactcatct
    12841 aatgatgagt tatttttatt cagttgtagt tgccatttct tttactcttt cacttgcaat
    12901 gtcataaact aaactatctt ctctgactga tattactatt attctcataa tattgttttc
    12961 cattactaaa ttataaacta ctcttattcc aatacctctt aactttatct taaaacaatt
    13021 tgtgagatta ttattccctt tattacctaa tggtttacca tatccatcag gactcggtag
    13081 agggttataa gaaacttttt caattgcctt taaaacttgt tttctttgag aattatctaa
    13141 tttttttaaa tctttatgtg aatcttttgt ataaaaaata ttccatttca ttattcaaaa
    13201 tccacctcaa tattttcaag gtctttttca ctaatatcca aatctttcat aagctcactt
    13261 tgagatatta attcttcttc atttatattt ttcattcttt tttctgtttc aagaagaagt
    13321 ttgtagtctt ctatggcatt tatcatttct tcatactttt caggtgtaat caaaacacat
    13381 gttggaatat tatttttcac aacaatttta cttccagatt tttttacttc atcaaatatt
    13441 ttatttgctt cccctttgtt gaatcgagaa ataggaacta tagtattcaa catattagcc
    13501 atcagtaaat ctctattgtt caacataata acacctccta atagtatata taaattataa
    13561 cataaccatt aatatttatc aattaattaa tatataaata catcaataaa tttaactata
    13621 ataatttatt ttagtataaa aagagccact tgtttaaggt ggcaatagat aagtagtaat
    13681 tcttgtgtaa aatttttaaa ttttctgtta tctgtattat atctttattc tactgctgtc
    13741 gtcaatataa tattaaattt aacatattgg taatttatgg tataatattt ttagagacta
    13801 cataaaaaaa ctattagggt gaatcttcat gtacataagc cttcccatgt catatcaaga
    13861 tgggaggtga tatgatatta tgaaatattt aatttgtttg ctaacgataa taacatttct
    13921 tacaactata ataatcagtt tgataaaatt ggttcagagt ttgaatagac ttcttaaaga
    13981 aatagatgag tttaagaaaa cgttgcaaaa aattaagaat cacccgaatg ccagttcagg
    14041 tgattcttct tccaattaat ttgcaatgct tatttatgaa gagacatcct agtgcaaata
    14101 gtttgtagtc tctttttttt atgtctttat gatataaatt tatatcattt atattactat
    14161 tatatcataa atacgttttt tataaacaat attttttatt agataaatat atattttcaa
    14221 aaaaaatctg actataaatt ataaaacgta agtaaatgag tgaataataa ataaagacca
    14281 attacatata ttaagaccta gtattagaaa taattttttt gttattttct tcaatcattt
    14341 tcctcatctt cttttcaaat tcaggcatta catctttagt tacattccct tgtacaacaa
    14401 caaatggtga attataatta actgctgata ttggagatgt acttcttgaa cgagaatttg
    14461 aaggaggatt ataattaggc atagcaaatt tacttaaatc taattcatcc aatatgtcat
    14521 taatatcttc taatgtatct ttaccttctt ttaatctatc gagccattcc tgcttagtga
    14581 cagaacccat tgccaacata ccatcttcat atttatttat gtattcaata atagcatctt
    14641 gaagtttctt aacctctcca tcaagaccta caaatttacc acttgaaatt gcttcattaa
    14701 ttaaatcaac taaattttca tctgagtatt ttttctctaa ctcttctttt aatttatctg
    14761 cttcttcttg tagtctgtca gactccttat catacatatc attgacttgg tcgtccacat
    14821 ggtcttgtac taaatcctgt aatttcttct gttcttcttt taattgtttt tgtaaatctt
    14881 taagtttctt ctgaccactt aaagaactat ctctttcagc tattgctatt tgcttttcta
    14941 aatcacttat tacatcttgt tgttcttcat aatcatcttt atatttggct tcttttcttg
    15001 aatcattgta agcatcttgt tgctttttaa gagaatcaat tttagcttta gtttctttat
    15061 ctatttcttt aagtctctct tcaagctctt ttttatacat gtctctaatt ttctcttgta
    15121 gactttgagc ttctttgagc tgttctttat aagcatcttg aatctcttta tttaaatttt
    15181 ctatttcttc tttattttgc ttaatttgat tattagcatc aggtaaatct ttaagaagta
    15241 aatctaaata ttttttagca ttttcttcta tttctttata tttatctgca tctttgttat
    15301 tttttagaaa ctctaattgt tgcccataat tctttatatc tttaccatca gcagaaaatt
    15361 caaacccttc ttttgataac ccttctctta actcttttgc agtatcttca tagactttaa
    15421 taacatcttt aatttcctta gcttgtttgg ctaataattc ttttttcttt tcaattaagt
    15481 ctaacttttc atctccttca gcatttttca taagaatgtc tattaagtct atttcatttt
    15541 gtatctcagt aacatgtttt tgtgctgagg ttaaatccgc ttccctagca atctctttta
    15601 attctttttt aaattcctct gctgctctag ttgattctat aagagaattt gttacttctt
    15661 gttgagcatc tgcaactttc ggtatctcag taaaagcaat ctttaaatat tcttcaacaa
    15721 cctttttttc ttcttctatt ttcttcttac gttcttcact ctttttacta cctttgtcgc
    15781 tctctgattg cttatctaat ttctctaatt ctttttctaa tgatattaat ttttcttcat
    15841 aactagttaa gttatcatca tctgaaaaag tgtacttata atctttttta agtctatctt
    15901 ttagtctatt cttttgagta ttaagtgcct tatctttttg gtctaacaat gttagttctt
    15961 ctttatataa agcgttttgt tcttcaagat atttaagttt atcttttcca cttgaatatt
    16021 tcattttctt atctaaaaga gatattctat ctgtaacttt agatatcgca ttttctaatt
    16081 cttttagtaa ctcaatgcta tattttactg ctgcatcaat agattttgta tctaatgcta
    16141 ttttaggagt tttagttata cgagagaatt tctctgtaag agttttaatt ggagatgtgg
    16201 ctcttgatac tgttcttgag aataaagatg gttttgttac aggagtttcg tcacttattg
    16261 gtgctggttc tgatgttcta ggttgggctg atagattagc tggaattgct tgtggagttt
    16321 ctatagaatt tatggattgc acactttttc tatcactctt taatccacct aatatattat
    16381 ttgcaaattg agaagcaatt cctcctagag tccctactgt acgaagatgt gctgttattg
    16441 taaaactctt atcacttagt tttttatttt cagtttgacg aattgtttct aaagcagcag
    16501 aattattcgc tttaagttta gcccacttgt cttttattgt ttttttatca acactatcta
    16561 tgccctcaat agctccttca atagctgcaa ttacttcaac ttgtttttca ggaggtaatt
    16621 tttctatttc agcaattaat gaattaatat ctccattagt tagtgatttt attatattta
    16681 tttttacgtc tttgtctagg tctaaagcat ttaaattctc aacttcatct aatgcatctg
    16741 gattatttac tataagatta gctataatgt ctttgctttc agggaaatca ttataaagtt
    16801 gttctattaa atataactta tcttcattat ttaacataaa attaagaact tgattttttt
    16861 gttcatctgg tgttgattca tatagttttg tagctctctc aagctcatct gcattttcta
    16921 cagcaaagct aacaacctta ctttttgttt cttctggaac attatcatat agtttttgaa
    16981 atgcttcagc cttttctgga tttttaatta taacttcggc aaatactttt ttatcttttt
    17041 tgtcttctaa tccatcatat atagatttca ttttatcaaa atcatctaaa ccatttaaat
    17101 ttatgctata atccatagct atagttggat tatccataag ccatttttgt acggcttcat
    17161 agtcctttag attttttaaa ctatcaacat tatcagttat aaatttatta gtaaaagttg
    17221 aatttgttgg aagatttttt actatatcag caaaaatttt aacttgttca gtctcaatac
    17281 ctgatgattc taattttaat tttacatcat ttcttccttc aagctgttta aatgaattta
    17341 aagtatttct aagctcttca tttttcttta acttaagttc aatttgtttt gttggaggtg
    17401 tatttaatat atcatctaca agtttttctg cttctttatc ttttgaaaat gcatatcctt
    17461 taggattctg cttgtctttt aaagcttctt tagtagcttt tttagcttct ttaacagggt
    17521 ctttcttatc tttatcgcca tttatttctt ttaatttttt ttgaatccat tcaatagcat
    17581 ctgatgctaa gtctttaacc tctatagtaa aaattttatt tgctatttca gaagaactaa
    17641 tagtctcaat atcatcttta gctttttcta tttcagcaat tatttctact cgtttatctg
    17701 gtggtaaact ttcaatagct ttgcctaaag catctatatc tccatcagat aaggctttgt
    17761 atatatttat tcttacatcc ttatctaaag gaattttatc caatgatgtt attaaatcct
    17821 gaacccctaa tttaccatca ttttgcttca aatatatttc tgtaattttc tcatcaggta
    17881 tatgttctaa ggcatctttt aaattaacag aattatacaa agcctctccc gcttctgcta
    17941 taaaatatgt tttaagttcc gcaggtactt tcttatatat ctctgatact tcaacagctt
    18001 tttctagtcc aactccatca gcttctaatt tagttttgag ttcagaaggt acttcggcat
    18061 acttagatgt taaatctaat atttttctac caccttcgtc tgctccttct tcttttatga
    18121 tagtttttac ttcttttgga aatttatcat aaattctttt tactgaatca gcttcttcta
    18181 atgttgtagt tggattagct tttatgactg tgattacttc ttctggaagc tcttcatatc
    18241 tttgctttaa gttacttatt atttgttctg cattagcttg acctgaatca tcactcaaaa
    18301 gtatttctgg agttatagta aatttacctt taccaaattt actgtctaaa tcattttgaa
    18361 gtttatttat atctgggtcg ccagtctgta actccattaa cacatccata gtgaatttca
    18421 atacatcagt agtacttgct cctgtcccta atagagcatc tatcatgccc ttgacttgac
    18481 taggaacttc cttagtattc ttaatatcag ttaatatatt tgcgtcaact tttacatctc
    18541 cagttattgt agttgtatct aatatattct gaatactatc aaattgattt tggagttgca
    18601 ttgcaagttt atcaccattt gctaaatcta gttttgtttt accaaactta gctaataatg
    18661 tatttataga tgtcatatct ttaattccat ttggatttac ttgcccaaat aaattttccc
    18721 atatattagc atctgtgtta gttgctttag ctatactctt agctgtttta tctattgttt
    18781 gattatattt ttctatatct tgtgttctag caaattcttc atttgcatcc ttaagagttt
    18841 tagataaatc tcctacatca actttcccac ttctaacagc agtaagcaat ttgttgactg
    18901 cctgttctgt gtctactaga gtatctggtg taacttcact aaaatcaaat aaactttcaa
    18961 gtccagcaaa actagactta tcattgcctt ctaatccact ataaagagtt ttattcttaa
    19021 tgttagaaaa tattccatct cctatttctt ttgaataccc ttgaatttta tctacttgat
    19081 ttctatacat ttcatcatat ttgaaatata ttttttcttc ttctgcttta gctgacatta
    19141 attcatttct ggctttatct cttgctctac cagttgaatt attatatttc tcgattgctt
    19201 tttcttgtct ttttttattc ttttcaactt ctgctgtata atcttcttct atttttacaa
    19261 gcttaccagt ttcgctttct ctcattcttt cttctaaagt tttatttaca tctttacttg
    19321 gagaatttaa ttttttagca gcagttttcg cattatcatg tttatcatag gacatcaatc
    19381 tttcttttgc attaatagct ctatctattt cagcaattaa atcagtaacc tgacctttta
    19441 aaataggtat accattttca tctgttccta taactgcatc tggttttatt tttgcaatct
    19501 gttgttttag ttcatttaat ctattattat cttctttaga cttattttct tttttagata
    19561 aattatcata ttcttctgca agtgcttgta attgaacttt ttggctttca tatgaattaa
    19621 tttgttgttt tgaagcttga atatttttct ttctagcttg ataagcattt tcttctctat
    19681 ttgcataatt ctccatagct tgtgctaata gacttacacc tgcaaatgca gcagttaaaa
    19741 ctaaagaatt tccaactgta gttgctatac ctttaccaaa atttacaatg ctactccctg
    19801 caaatgcctt accaatatta ccaagcccat cacttattgt atcttttcta cttttagaaa
    19861 caacttttaa tttttgatta tatttttcat atgactttgt tctgtcttca tttattttta
    19921 tttctttagc tgttgccttt tttaaactgt tggttgttga tgtatatttt cctacaatgc
    19981 cattttgact atttatagtt ctattaacaa cttgatttga tttagcattg ttttttgaag
    20041 cattagtatt tttatttata gcacttgtat attgattagt aaattttgta gctctttcaa
    20101 agtctttaaa tttaacagat tttctattgt tttgaaaggc actaaatata cttcctccta
    20161 aattcgtgat tggtttacca gtacctaatg ctttaattgt cataaataaa gacgataaac
    20221 ctgctagggc tacaggaagc gaaacatgca ttttgtcagc cgctttagtt ataccattta
    20281 aaattcctgt aataccagat aatccatcta aactagtctt aaacatatct gtagatatag
    20341 tatctgtaac taattgttta agactttctt ttaattttat aatcttacct tctgctgaat
    20401 ttatgaatct ctcattctct ttactggcac tacctagcac ttctccaccc agccatgcac
    20461 tttggaattt ttttacctgg ttccaattat ccatgacagc catgaaagta tttatgtggt
    20521 ttttacctga acaaaatctt caattaagtt cgctatactt aactcgttct cttatgaact
    20581 gctatatgtt tccatataga tgagactata tcttcatcct ataaggatgc tccccatttc
    20641 cactatcaat agcttatagt gtacggttta taacctagtc gttgaacctt actctcattg
    20701 agttttggct gctgattgtc cctatctttt agtttttcac actttggtac taaaagccta
    20761 acgggagttt ccagcaatta aaggagttta tcattatata ttactatata aggcgactaa
    20821 aattaatcgc ttcggcaata ccactttttt gatttttagt taaggcatct tcgccaacac
    20881 tatgccactt ttctgccaac tcatctaaaa ttgacatcat atctcttact tggccagttt
    20941 gcttatctaa cacatttatt tttgctgttt cttgtaaagt ttttgctgtt ttattgaggc
    21001 tgatttttcc tgaatctgct gaagctttga taccactcat gtttatacca attgttttga
    21061 gtgctgtacc tactttttca gcattttgta cagattcatt tcctccaact atcaaagcaa
    21121 cagagtcttc cattgaaacg cctgctgatg ataacatact tgcacttctt tgtaatgcag
    21181 ctcctacatc gccagttgtt attgcaaaat tattacctgc atagttcgat aaatcaagaa
    21241 attttgtaag attatcataa tctttactca ttcctttgat ttgaactcta gtatctttaa
    21301 ttggttttaa tgcttttgtc attccaccat aagcggacat aacactagtt aagtacttat
    21361 cagcagtttc ttggtctaaa tcaccaacat ttgcaaaaac tgctgattgt ttagctatct
    21421 tcaaactgtc tgataccgat tttacaccag tttgtagagc tttagatgcc ccctgaatta
    21481 tatcctctga tgctctagct gtatctttcc ctattgatat tgcttcattt tttacattct
    21541 ttaattgctc acttgtacct tcaaaattat caggtgctac tttcatcata tctcttaaag
    21601 cactatctaa ttcaacgata gttgttttaa tatttcttac accatttgta atagacatac
    21661 ctatcatatt acctaaagta taagttctca tcgaattata taggtcacta aaaaatccat
    21721 ttgttgcttt tacactagtt cctaatcctg tgaaattaga tttcatattg cttaatctgc
    21781 tttttattga atctaattcc tttacttttt gacctagagg cataccattt aattgcatta
    21841 attctttttc tagtttatca attccagcag ttgattgacc caattctaaa catttttgtc
    21901 taagcctatt taaatctgaa attactttgg aaagattcat attgaactta gcatctaatt
    21961 tagtattttt agtagcattt tctacttctt taactttatt ttttaattgt tctagttttt
    22021 gtatttctga ttgtatttga ttagaagtta gatttttaag attcaaattt tgaattgact
    22081 ttaatgaatt tgataaagct tgtagtttag atgtatctgc atatccagac ttacccaatg
    22141 tttctatttt attagctaat tttccagctt cattttgaag agttttaaat tgagaagcca
    22201 tttttgtatt catatctggt attttcatat tagccaactt agactgaaca tttgataaat
    22261 ctgatagagc ctttgaattt agaccaccta atttaatatt agataatctt ttcaattctc
    22321 ctgataattt gttaatttct cctatttgct tattgtctaa aatatttgtc tgagtaaatt
    22381 tctttaattg tctttgagta gactctattt ttttcctaaa gttatcgtat tgagaagtta
    22441 atttatttat attcccattt gaattacctt ttccaccaaa taatccattt tgggtttctc
    22501 tactaagttt attaatttgt tttaatgtgt tctctaattg ctttaaatta tttaatgagg
    22561 atgcattcat ctccacattt aactttatat tattttcttt tgcagatgtc ttcagtgatg
    22621 ctaattgttt cctagctttt ttatcatcaa gctctatact ggtcttaatc ttaaattctt
    22681 ctgccattta accaactcct ttttaaagca taaaaaaaga cagttaatat actgtcttaa
    22741 tatttttatt taattttctc taataatact tttttctttt cattaaattc ttcttctgtt
    22801 aatatctctt ggtctttcaa actctgtaat tcttttaatg aatttgaaat ttttgatata
    22861 tcatcatcat ctttttttat atcattattg ctttctattt tagcattttt aaatttggct
    22921 gcttcattct ctacaactaa tttaaatctt tccatttctt ttattttttc ttgaatatct
    22981 gcattattta tatttttata ttgtggaata taaaatactt cataagtatt aagttcaaat
    23041 atcaaagtta aatatatttt ttctacaaaa gtatatttat catatgtagg aactatagat
    23101 attatcctca tctgattttt ttcactaact tgcatgctaa acttaatgct tactaaatct
    23161 tctatatttt ttttaactgc tgtcttaaat ccagcatgaa tgatagatat tttaccatta
    23221 ttgcttaata tcacactgtc actgtttgaa ttaccaaaag cttgacattt agccattgaa
    23281 atattttttt gtatagcctt ttccaccttt gttttttctc tatttctttc tgctattctt
    23341 tctaatctag cttctttttc tttagcatta tccattacgt ttcttataaa gcaataaaca
    23401 ataatatatc ctacacctag ccctattaaa ataaaatgac ctaaatattc ttccataaca
    23461 tctcccccta tcctgatact tcaattatat caagaatata ctattaggaa aattattaca
    23521 attcgacatt attttctttt aattttttct ttaatactat agtagttatt ggttcatcat
    23581 aattccaata aattaattta acattatttt catcacatag ccttttcttt tttttatctc
    23641 ttaatttatt tttttcaaga gtttcttccc ctccaaaaaa atctacactc ttaaaatgtt
    23701 gttgtccttg atactcaaaa gccaaattaa tagagggaac aaatacatct aaagtttgac
    23761 catttaacca ctcaggtcta tattgatgtg ttgcatcttt aaacttttta caaattactt
    23821 taaacatatt aatctcactt ttccatttat aagccatttc atcatttaaa atcatttttt
    23881 tctggataag cgctttttct tctaaataat ttattttttc taatgatgat gtatcaattt
    23941 tctcatactt attttgcatt ggagtcatta ttttccctct taaaaaatac actagttcaa
    24001 attcattatc aaaataccct ttttccatta ttttgtttat tacatttcta gcatgaagta
    24061 tttctattgg gtcattatca gacctagaaa tatctcctaa aaaatgtgtt aaattatttg
    24121 gttttggata acaaaccttt ttaccctcaa acaaacatag attttctata aattttatat
    24181 ctgtatcata aattttataa cctgaaaacc catgttgcat atagctagaa ataagtttca
    24241 acattaatgc tatttctttt ttttgttctt ttttaaacac aactttgtga tttacacttt
    24301 tgtcatcttc aaatatatta ggaagtatta tatgtttata agcactattg gctaactcac
    24361 aagctatata atatttttct ttagagcaac tgctaaaaaa cattgtatat gtatcttttt
    24421 ctttatattc atctcttatt tcttctgata tgctatcaaa taaattgttt atttccttaa
    24481 atccatccct atattttaac ttatccaaat ctcttccagt tttcatcata catgagattt
    24541 cttcgtccca agttgttaac aacaaatatt ctaaatctct attaataaat tcttgtttta
    24601 tttcttcaag ctttttgaaa tataatttac tttttttccc acatctatta tctttaatat
    24661 attcacttat taacataaca ttatctcctt tattctgata cattaattgt atcaattcta
    24721 aaggaaaatt tatactacaa aaggaaatag aagccaaaac tcctatttcc acaaaatcat
    24781 ttactcaaat atttattaat atcttcttta ctagcttctt ctatgtaatc tatcatacag
    24841 attggaatat ccctactgct agaaacatct cctatttttt ctactcttat tttctcattt
    24901 cttacactct ttaatatacc aataaatcca tagtactcat ggtcatatat agcatatgtt
    24961 ttacctatct caaccataac tcctcttatg taatcattat ttatcatgaa tctcttaagt
    25021 actttgttat tctctttcaa tatcttattt acaaaatata tttgtccttt tccagttaca
    25081 acaggagttt gtcttattac agtatttcca tctttatcta tcccagtact ctcagaaacc
    25141 tctaatactt tcaaatccat tgacttttga gttggagtat tatggtcagc tcttttcttc
    25201 ctaattagat attcattatt tctcatccac tcaaacaatc tattctgccc tatatctact
    25261 ccattctgat ttaatatctt agatagttga gcaattagta ttgagcttga tgaactttct
    25321 atagcattag ctagttcaag tttaggttta tttttctctt gctctacttt taacttttct
    25381 ttagtagctc tctctttctt tagttctgta agtaatttta tagtccaatc tgggtcattg
    25441 attgccttct ctaatgcttc attagtcata taagctccat gttctcttat tgatggaaga
    25501 acttcatcaa atacccaacg ctcaaatttt tcagcacttg gtaattcgct atttataatt
    25561 aatctataca tatcaccttc tggtattata ttcacttcca aagttttagt tttactttgt
    25621 gggtgaggta tgtggtgttt caccacccac ctacaatgtt gtttaattgc atttgttgtg
    25681 tccttatacc caagagcttt tgcaatatct gttgcgacaa aatagggttc attttcaatt
    25741 ctaattgttc ttatttctcc aaataattca ttgttaaagc ttattattct tttttcattt
    25801 tctctattaa ttatctccat aattaatccc tccttataag ttgtattttt tataagaagc
    25861 tgatataatc attctattca agttgataat tatatcagct atttaagaag tcttactcgc
    25921 cgtccaaagt ttgtaaggct tctttttaat tactaaaagt aattttatca cttaaagtaa
    25981 tttatatttt tataatatac tccacataat gtaatgtcaa gtataatatt ttattacttt
    26041 atgtggtata ataattataa agatatcttg gaggtgaaaa atgtttggag aaagattaaa
    26101 aaaacttaga attaagtttg gattaaagca acatgaatta gctgaaatat taaatgtatc
    26161 acaaagcact ataggtatgt atgaaaacga ccaaagaact ccaccagcag agtctatagt
    26221 taaactagct gaatacttta atgtcactac agattatctt ttaggtcata caaaaaccaa
    26281 ctattcagtc agtgcaaata tacctggtat gccatcaatc atatgcgaag atacttccat
    26341 ctatgatata gttgatgaaa aaaaagacat taagtcttta gaagatataa ataaattctt
    26401 agaaaataat aattataatg acgaagtcaa agaagttctt aaaaaatata tacaactaga
    26461 tgaaatggat agaaaagcta tagatagaat gatagataat gcatatgaga gactaaaaga
    26521 ggataattaa tatatacctc ttttttaaaa ttatgattgt catatacctg tcactattga
    26581 aatcgctaat atacaaatca ctcaattaaa aaagacaatc aactgactgc cttttattta
    26641 tatataataa tttttactta tctgattaat tctcttcatc tgaatattct acttgaagac
    26701 catatatagc tacatatgct ctaaagtcaa atatttcatt tttaaatttt tccaaatcat
    26761 cttgagaatt agatttttta tatgccttag catatttaac catattgtca taggaagtct
    26821 tagctgctga aaaatggtct aatgctttac taactctttc atcattttta aactttcctt
    26881 tattattttc tatataactt acatcaatat ttttatctga atagaagtca ggaacaatct
    26941 ttttaacttt ttcataaaga ttttcatcta aagggtctat atctttagga atagaatctg
    27001 aaataatctc atactctttc attgcttttt caatgttcat catcatggtt tctgaagtag
    27061 acttagcctt gtttaattca ctatttgatt ttattgaatt ctctaaagct ctataatttg
    27121 atagaaattc atctgtttta gtgttattac tagcagaata atctacataa ctcccacttg
    27181 gctcagttgc aaaactatga aaatctgtat atgaattata gaatttttct attgtactta
    27241 aaatatcatt taaatcctca ctaccttcag gaacagattt caatttacta tatattttta
    27301 gaagttcatc atcatatttt tttgacttct ctatttcatc acttttatcc aacattgcag
    27361 cgaaaatagc agcatcaata ttagaaccat gtttcttttc ataaatattt tctttccaat
    27421 aagtttgaat agtgtcagca atatcttcta aattagcacc tgctacataa cttttttctt
    27481 gaaaatcttt aatagtcatt atgtatttcg ccctagcttc ttgttgtttt ttttccttga
    27541 tattgatact ggtgaaaatc cccactatga ccatcaatat tataccagca atttttattt
    27601 attgatgctt ttttacttat tacagtcttt tcatctacct tcttaccaca cttagaacaa
    27661 aaaagttgtc cttctaataa cttttctcca catgatatac aaaatttagt actatcattt
    27721 tcctgtgata ctttgttttc atcttcactc atataaatta ccccctataa tatctgtcat
    27781 aagcttacag tagctttact gtccctcaaa gcttattcta ctaacactat aattatagca
    27841 ggaaacatgt agaattacct ccactaattg tatatatttg taaaataaag aattatatgt
    27901 aaaaatcttt taaatgtata cttatcatgc ctctgtcatc atttaattat aacaaaaaaa
    27961 agcctacttt aaatagactt tatcttttat atcaaaatat aatttatcta gtttttaaat
    28021 atttataaat tttaaactta aggctagtta ggagctatgg aatatcatat taatccttaa
    28081 taataatcaa ttcacatgaa aaaccattcc agcaaatcat taactcgcaa gtaatagctc
    28141 ctcaatcctt actataatta taatatatat attataatta gtcaatattc ctacaactat
    28201 aattttataa tttttatccc aaatttatct ttatttttta cattaccatc ataactaaac
    28261 cttttgatag tattataaat attatattta tttaattttt tattagaaac ttttctagct
    28321 attatatttg gaataaaatc tgctatttgc aatcctgcta tattttcatc cttgcttgga
    28381 aattcaatgt ctaacaatct ctcctgtata gcatatggat ttataaaaag tgtccccatt
    28441 gttttaatca tattaaattt cattttcatt attttagaat tagaatctcc attatgctca
    28501 taaattatac gacctttaga atcattattt ttcaaaaaat gaacatagtt ttctattaat
    28561 atctgtaaag ccattaatgt tctatcgttt tgaatttctt tattgtacaa cttatcaagt
    28621 tcatcatgct ttatacatac tgctaatgtc gttatttttt tattccttat tattttttct
    28681 aaacctctat acaatatttt cacgttttga ttttttctaa aaatcctatt gtgaggtttt
    28741 actaaatttt gatttttttt atcataacca ttattagctt gttttatttc tacttcatgc
    28801 aatattaaag cctcataatt tatattatct ttccatattt gatattttat tttatttaaa
    28861 tcttttgtta gctcattaca atcatattta tcttccacta ttattccagc tatacaaaat
    28921 actttattta tccaattacc atctttttca tcatgagttt cactctcatc taaatataga
    28981 ttatatattt tccccactat aaaatcccct tattttaaat atgaatatac aagctatatt
    29041 ataacatatt tttacattaa ttttaagtgg ataagtaggt agataaacta ataaaagata
    29101 aaaacaacct aaaataagta tctcaacaat cagagatgct tatttttatt tataatatat
    29161 aaacataatt atctttgtca tacctatgtc atcattaaaa caactaaaca ccaaacaaaa
    29221 tgttcctctc aggaacactt gttgaaattc caatactttc aaccataaaa atcaacctct
    29281 tatgttcgat tctaagcaat taaggtatta tatatctttc aatatttcca agtgtattat
    29341 acttgtcaca cacatgtcat cattgaaata actacaacat aaatgattca atttaaaaaa
    29401 caatctaaat tgattatctt taatatttat taatacatct tgatatttat attacaatag
    29461 aataaacctt ctattatctt ataataataa aaggtttatt ctatctccac accttaaagg
    29521 tgtactatgg tcactcgctt tatctatatt aatataataa taaacgtctt ataaatttta
    29581 caatttaatc tataagacct attttataac ttctatattc gtcatctaca aaataaatta
    29641 tattgttaaa caataaagaa gctataatca tttttctttg cctgattagc catttttatt
    29701 atgtctccag tccaaatatc atcatcataa ttatatatta aatattttgg aatattgact
    29761 ttattatttg taaaactatc tttttttaat tcttactttt ctattatctt accacaagat
    29821 tccctaaaat gtatattagg ataatctaat tttcttgtaa cctctaatac ttcctcgatg
    29881 tattcaaatt taaatgttaa ttaaaacaat tatacctctc tccttatatc aatatgttat
    29941 atacaagtat atttcacaat atacttgtat atgtttttgc atcaatcaat gtattagaac
    30001 attgagaaac aattctaaac cgcttatcta agcaaatcaa ctaaactacc tatctaggtt
    30061 aaattgctca ctatatgtta gagcatcacc gctttttaat tttccactta tgatatacat
    30121 ctactagtgg ataacataca acccttagaa aactctataa cttaatagac actcgatatt
    30181 atctatttta ctggtacgcc taattcattc attttagact taaaacactt aggtactctc
    30241 tcttgtgctt tagaattact ctcttccatt atatttgttt gaggtctata tccgccaaca
    30301 ccccagactt tccccttttc taatctttcc attggaaatg ctgaattacg tgtaaatgca
    30361 tccacccaat ttccattatt ttgtatctct gaagtgacag aattagaaga gagttctgta
    30421 acatctatag catctaataa ttgtcctgtt ctacctcccc aaacattagg attccattct
    30481 ccaactggag tataaccaga ataaacctgt ttatttactt cttccttcat aatttctttc
    30541 atttcttttc caacttctgg catagatgca gcaatcttat tttttgtata agcaactagc
    30601 tcatccaatg atttaaatac catctaattc accaccttgt ctttaatatt attcattttt
    30661 tcaatttctt cagtttcttc aatttctttt aaaaccctgt cttgtaatat ctcattcttc
    30721 atctgaccta atttaacatc agtgttcatt aataaagatg cagttaattc atttcctatt
    30781 tgacatatgt gatacatcac agtttctaat tcgctagata tattgctatc tactaaatct
    30841 tctatttcaa tatttaactc tatattagtc aatttatcaa tcaacatttt aagaatatct
    30901 tcttgagaca atgctaaatc aggattctcc ataccaaccc atattttatt taatatctct
    30961 tctttagtct ccttatcagg atttctaact tctatatatt cctctttacc attctcatct
    31021 ataattggta ttatagccct aacttcatct tgtattaatt tatctacttg tattttattc
    31081 atgtttacct ctcccttatt ttattattgg atatttacac ttaatagaaa ctttacagtt
    31141 tccagtaaac ttcaatatat ttacacctct tcttaatcta atccactttc tattaataat
    31201 attaaaccta ttctctccat tactatttaa aacagtatag tataaattat ctattgttat
    31261 tttttcattt aattctaatc cacttataac taaattgtct tcttcattat cgctgatagt
    31321 agaatttcta atagttatat ctccttcttt tagacattca atatcaatta ctggagcata
    31381 ttcttcatct acattagaca cattatttag tttaatttcc cttgtatcct tgacagttat
    31441 aactttttga aagcttctat aagcataatt tgtatatggt tgaaactcta tttctaatac
    31501 gcctttttta tcttttgtat atctttttat tatttttctc gctttgaaat agtatatttc
    31561 ttctatattg tcataactga taaaaggttt aaattctctc tgccaaaacc aattgcatat
    31621 gttttctagc gtataatcat cccattcata agcctcccca tgttcgctac ataaacagaa
    31681 ttgtaatgtt ataggttcta tagtagtttc atcttcactg taacaaggat ttttattaaa
    31741 actgctatca gatttaattg cttcttcata aggcaatcca tattcattca gtatttcatc
    31801 atcacctaat gtaactaatt tgatgttcat agattcactt gaaacattat caaataaaaa
    31861 cttatcatct aaaaatacca atttatcacc ttctttcatt tttttaagtt caaatccgat
    31921 taaaaccaca tttaaacgta aaaaaataat ccctactcaa ttaagagtag ggcattttac
    31981 tatttcttag gtttagtatc tttttcatct tctaattcaa cacctagcat tgaagccatt
    32041 ctagcaggat taagattttc atctcctata aatgtgaatg tagcatactc tttattttca
    32101 tctggtaaaa catctaatgt catattaaat ccagatggat tctcagcagt aagatttaac
    32161 tctatacttc tttgtgcttt tgcatttgga acactcatgt ataaaaccat atattcacca
    32221 tccacagttt taaccattac ctcagcttct acaacgtaat ttggtgcagt agattcttct
    32281 tttattttta caacttttgc ttttggtatt tcttctaaat agaatactgc tactttatct
    32341 cccgcattaa aatcggctgt agatattgtt atttctgtat tagctcctgt aactgatgaa
    32401 gtgaattgta attttttaat tatagatatt ccatcacttt ctatactata tacagatatg
    32461 ctatttgcaa ctggctttat attttctaaa gtaactttct tagtactatc agatgttaat
    32521 acttttcttt tcccaacctt tgcagttttt tcatctatat cagaagataa taacatcgct
    32581 aattgagcca tttgtattac ttcttgttcc attgttaaac ttgctgttat tgctccatca
    32641 aaagctattg tatttgcacc tttagctttt gcataaactg attctgaatc catcttaaaa
    32701 ttaaaagcat ttaaatcctg tgaataaaac aatacttctc ctgttacttt attttttact
    32761 attacattac ctgcatcttt cactgcaaat cttttcatat tataaaatca tcctctcatt
    32821 ttttgcataa aaaatagcac tgctatttaa cagtgctaag tggtattttt atctctttag
    32881 accaatgctt cattttatcc atatctgttt gatatttaaa tgaccatgca tagcctaaac
    32941 tttcattata gtttttaaat tgtatcttag tcttataaac attaattaat tgccaataag
    33001 tcatttttaa aataacatct attggtacat atccatctat gttttgaact acatttatat
    33061 aatcacataa gtgatatgct tctttttctc ttttctttct ttccttctct ttaaagtgtg
    33121 caatcaactg tttttctctt tcagagccag tattttcaat ccacttatct tcatcatctt
    33181 taaataaatt ctttttatca atacaaaaca tctctaaaat caaatctgat actagtccaa
    33241 aatcctctct acttataaaa gcatttttct ttttatcatc aaatttaatt aaaataccaa
    33301 ttttaatatt attcatatac tcaatatttt taatatcagt tttatataat atagataaag
    33361 atttttttat cttatcacta agtaactcaa tttcttcaga agaatccaag ataggtatag
    33421 catcatattt acatttcaat tcaaatattt tctcgttaca tagctgagaa tagctctttt
    33481 caagtactaa aaatggatta actatctcta aattagccat atcaaattta ataagttctt
    33541 caatagtagg ttgatataca gttcctaatg tttcacctag tttaattggt aatcctgtga
    33601 tataataatt ttccaacatt acatatcacc aaaactttca gctgatacag ttataacaaa
    33661 tccgttataa tcagtattta aattatacat ttgatataca ttttctaact taatcttacc
    33721 tataccagct atttcctcat tttgagttac aatatcaact atacaacata ctaatgcaac
    33781 atctcttaag ccatttgctg tactttggca ttcatcatga caaacaacac caatttctat
    33841 ctttgttttt ttaattgtcc tacttccttc aaagcatggc ctatattctg acattattat
    33901 aaaaactgaa atatctgctt cttttaatac tttttctact cttctattta gaaatacttt
    33961 tttgtttcta agttctttaa caggattttt tatatcaggc atggataaaa tatctttttg
    34021 ggattcatca ttataaatca taaatttagc gaagtcttga tttgacatta gagttgctcc
    34081 tatattactt atcatcttgt tagggaaagc catataaacc catatatcta cccccttagt
    34141 gttatttttt tagtatctat tgttttattt gtatctttat ctttagccaa tagcaaggct
    34201 tcaaagccag aatatttagc caatgtatta gcctgtatga cacatttttt ctcatcttga
    34261 ttaattatat tacaatatcc gtattgcttg tctaagagcc attcaactcc ttgagaatgg
    34321 tctattttgt attcattttc ttcgcctaga ttaataaatc catcacccat aattttacta
    34381 aaaggaataa tcacactctc attttcagat aaatcattcc aagcaatatt atttattgta
    34441 tcatcttttg aaatcaatgc atcttgtaaa caaatagctt taataagacc atctgcccct
    34501 gtttctctgc cattatactc aaagtcatta atactagtaa ctctaaatac agttttacca
    34561 gttaacatta ttctagtgtc aatatctata gttttagtga caggattact tccaaaataa
    34621 agctgtcttt ttgtatctga gatagaagta tatttattat ctgccatacc atcagaatat
    34681 aaggttaaat tttcaacagc tatagggatt ttatacatct gacctttata tttataatta
    34741 aagaattgat tgcatctttt tattatgaaa tgtttatatg tatccatttc tttatgttct
    34801 ttaaatatag ttaaccaata acaattatca tagaaaagat aacaacccac atctacatct
    34861 aaatcagatt caactaatag atttttttca tctaaagctc ttttatcatt attagttata
    34921 tcattaattg caactatagc tcttttagta tcttctgtta tacaaatttc atctatatca
    34981 gttattggta cttcaataca ggttggtgtt tcttttagat atttcttaaa acttaatcta
    35041 agttgtaata ttcttttttc tttaggagtt gaacaaccaa gtccaattct tttttttgta
    35101 tcacttaagt aactcatgct agttccatcc ttcaaaattt tttagcatgt atctttgttg
    35161 atatttatta aatctagttc tcaattgctc ttctcttgct tgaagtttag ccaacatatt
    35221 agcacctgat ttagcattat aatcagaatc agttagcatc tgttttaaat tttcttctct
    35281 atttatctta ggttgtaacc aatgtatttg cataccatat gataatattt taatttcatc
    35341 taaatctaaa tcagatacta tttctcctaa atatttgtat ttgaaaatta tctcttctgt
    35401 agtttctaca acaaaactta ttataaattt ttcatcttca aagcttattg tataatcttt
    35461 atctaattcg tattcttctt ttgtatcttt tcccatcaaa gttatctctg catttttatt
    35521 actataatta gatgtataac ttaattgagc agcaggaata atttctccac ctttttcatc
    35581 aacatatttt atagtcaaat cttttttaca ttgattaaaa tcaactatag catcttctaa
    35641 ataactgtac atcatttttt ctattatttc atttgatagt aataacatct cttcatcatt
    35701 aataccatcc aaaaactttt tatatatttt tacaagtggt gtacccaaat attccaccac
    35761 ctttaactaa acaagtacaa atcttccatt ccaattcttt tagctaatag tttagccttt
    35821 agcccagaat caaacttttt ctttttatgt aaatctattg ccctctcagc taatcttctt
    35881 gttaactcaa cattattttt atttaatatt ttttcaaaag aatttatatc aactttatca
    35941 gataagaaat attctaaata gtcttcatta ggatttctta tatattcata taaactattc
    36001 aatcctagaa aatctattat gtccattgga gtacattcaa catctaaaga atctacatcc
    36061 gaaattatta atctatgttc ttcaaaaaaa cctggacttc ttcttactat tctataaaga
    36121 gtatctaaat ctataaattc agttgaatct tttgaaccta ctttagataa agaaaaaatc
    36181 tgttgttttt ctcttgggtc aatataatca acatcccatg tggatatatt ttttatttct
    36241 atatctattt cctgtttttt ttgttttagt tttctttgta gttctaatct atttaatcta
    36301 gcttcttttt tatttaaagt agactttata tctttttcta aagtattaac tttgacttct
    36361 gttttagaaa tattttcttt tttagctctt gccataataa tctccctccc ataaaaaaaa
    36421 gaaggtggat aaccaccttc taattcaatt attgtatttt ataaactcca aatttagcag
    36481 cagttacaac tcctaaatgt attttttgag ccataaaata ttctatttgt tggtcatctc
    36541 tttctttttc atcagtattt tctatgacca atacatctcc ttcagtacca agtttgatta
    36601 tcttctctcc atcaggtatt acatagatag ccttattatc taaagcccac tctttacctt
    36661 ctgctgcatt ttcatcataa gcatttggta aactaagtac tttatatcca cctctaaatg
    36721 tttgtataaa accatatttt cttttttctt ctttttctaa atcagtttga acaccttcta
    36781 aattacttaa tgcaagtgga gtaccatata taataggctt tttaccagta gccccttcta
    36841 ccttagctat caattccaat aatactttgt ctgaattacc tgtagcttga aacttagcat
    36901 ttattgttga atatgcacct tcaaatgtct tcgctattct tctagcaata tcataatgat
    36961 atgaatctga taccctattc acaaatacaa cccaatttat tcttcctgtt ataaatctct
    37021 ctgcttcttc atatatagca acagataatt taaatgctgt tgtaggaact tttttattaa
    37081 gtaatctttg tcttcttgta ctattaacac catctgctat atttgcaact ttaaataaat
    37141 tagtattttc aacagtaaat tcttttttat ctcctaaatc aaagttctca aaatcacaaa
    37201 acggactaaa tacttcctca tttaatctat taatatcatc agatattaat tctgatatta
    37261 aattataaaa tccccattta ttttcttgga atttataata attatatttt tctcctccca
    37321 tcatttcttt taatttattc tttattgcac tttcagcatc tctatatgtt attgtgtttc
    37381 catctctatc tgtatattct ctaaatgtat ctgtatatag ctcatgagct attctcttta
    37441 aagtttttgc tgttgccatt aatttacaca cttccttttc tatttttttg cataaaaaaa
    37501 taacagttat agactgttat ctcctgtttg ttaattttat ttgattttat aaaactttta
    37561 ttgtaaccga atcttgacct tcatagttcc ataattctaa tacttctgct actggagttt
    37621 tagcatctgc tgtaggcaat ttttcaaact gaaacgaatc agattttaat tgtaacttgt
    37681 cttttactgc aatactttta tctgctatat gtaatagaga tatagttacc tcatctcctt
    37741 tttttagtcg tctacatcta catatctgac caggagaaac ttcgtaatct ctttcatcta
    37801 atctttcatc atacatagtt gctgggtcat caactatacc ccaatctaat gtgtcatttg
    37861 taactttata tattttatgg gtatccctac catactccgt gtcttcaagt tctccaatat
    37921 ttattacagc accattttct aaatttattg gattggtatc ctctgatgga acaacatatt
    37981 tacctgttaa aacatcagga ttttttactt tatctgtttg tattattgct ttatctttct
    38041 tcatgtaaat tcctcctatt attctttatc tgaatatttt tttataaaag atatttcttc
    38101 tggttcacta aaactatcat tattattact tataggtatt tttatcgtat tatttttatc
    38161 atcatttata ctaaaatttt ccttttcgct ttgtttattg ctaagagttt ttaatgcaaa
    38221 tatgtaaccc aattctttct tgtattcatc taatgtaatt tccttattat aagcttttat
    38281 ttttatatct ttaatttcat cttctgctaa ttcaaatttt tgagctacat catcaacttt
    38341 agatttaaat aactcaaatt ctttttcttc tttgaatgcc tgtaatggct ctaaactggc
    38401 ttttaaatta gatatttctt tttgcttttc agtaaatttc tctattattt ctttttttaa
    38461 tttttcttgt ctactaaaaa cctgtactat ttctccttct tgtttttccc tccaagtttg
    38521 tatatatgat tttttatttt cataatccaa aatgacagca tcttcattaa ctatatatgg
    38581 aataccataa taataccccc agttaatttc atcttcaact atagcaatat tctcttctgg
    38641 tattaaatca ttataataaa aagcttgtac ttcaactttt tcaccatacc aattctcagt
    38701 ttcgactttg tattctttta acttatttct tatttcagta ctaagattac tcactgctaa
    38761 agcatatcct tcagaatttt tattaagttt ttgattctta tttggcaaat tcttttcccc
    38821 ctctccatgt tctaatgcat aaatttctga gcatattttt gatatttctt ctttataatt
    38881 aatttttctt gaaaatttag ttaaacaaca atttgaaccc atagctccct ttacatcaga
    38941 accaagacat gtaattccat gatatacata gtcttttata ttataaaatc catctgaatc
    39001 atctaattga taatcattta tatctatttc cattgaaatt tctatttcat cagaatccat
    39061 aattatatcg taagcatgat tgctatatga tttatatata tatcctttac atttaacata
    39121 cttctgccca tcaatttcaa ctttttcata tttatttgtt tctggtataa cgccaattat
    39181 tcgttcttca taatattctt ctaatataaa cccttcatct gtttgaacta cttgtgttaa
    39241 aacattatga ccatcaaagt catattttcc atcttcattt atttttacat atcctagaat
    39301 tggaacattt tttaatgttg gttcagcttt atcaatagct tcttcataaa atttagttcc
    39361 atttggattt gtaccttcat gcataacata gatatacact ggcaaaagat tactatttag
    39421 ttcttccaat ttttttttat ctgaataatg ttttaaatta caaggtaatt ttaatatttt
    39481 tatttttttc acctcctttt aaaaacgtat tttgctagta aatataaatc ttttcatttc
    39541 ttcattactg aaattattta ttaattttga tttattttca aaaacatata aagtcttatt
    39601 attcaacttg ttttcacata taaaacgata tcctttttcc attaataatt tcttatcatc
    39661 ttcagaaaaa gcatatataa acttactcat aattaatcat tctccccatt tccttttgct
    39721 tgagtagaat taccattatc tgtccctata tcagatttat ctggtctacc actgctttga
    39781 gtatgagatg tttgttgagg tattaaaaac tcatcaaatc ccattaattt ttctgcttgt
    39841 aaagtgttta tagcttgaag tggagtaaac ccagtacttg caataaacaa gcttttactc
    39901 cctccgtatc ccatatcttc tcgatactgt ttggataaat tcattttatt aaagtgagta
    39961 gttccaataa acttcatatt aaataaattt gccttcttgt ctttatttag ttcaaagtta
    40021 acccaatttt ctatcatttg ttgaatcctc ataggaatta agctatctgc aataatacca
    40081 tttaagatag attcattatt tatcttgtca gagttaagta aggctgtatt tattccagcg
    40141 ttatcaaata tgaactcttt tgcttctttt acataatcat ttattttaga ttttccatct
    40201 gaaagagtat gtgtttccaa ctctaaagga tttgtagtta ttgctgttcc ttttggtaaa
    40261 tttgcttttg ttgaattgtg gtatatggga attaaattaa ggtctactag tggttcatca
    40321 tttttgccaa atggtatctt ttgatgtatt aatttaatac tttctattac tgcatttgtg
    40381 ctttttaaat ctttcatatc ttcaagctcc attaaatcgt caaatataaa gcaaaaaaat
    40441 ggaactcctt tcactgaatc taaatcataa ttaaatgcta ctgctttatc acttaattga
    40501 aaatatgtat tatcaattaa ttcttctcgt gtaagtaaat tagatttata ttttttatat
    40561 atgtttttaa tttcttctgg aaaggatatt atgtttttgt cagtaagttt ttttatattt
    40621 atagcgtatc tcattacatt attttctatc attgttatca tacaaaattt tgctggtatc
    40681 tgttgtaaaa ccatccctga attatcttct atcttatata aataaacctc tcctaattcc
    40741 aatacttttt cggttatcca agctgatgta aattttatat tatatttttc taattgactc
    40801 gccgaattca tatatgcttt tgttattttt tcttttgttt ttaatctact tatgtctttt
    40861 gggtataaaa tatggtcaaa agtattcata ttagatatta aatttaaaac tcttctatat
    40921 gtaccagatg tagcttttaa tatcatactt gcatcctgaa gtatatctgt atttgaaatt
    40981 tgatatggat tggagagagc ttttcttaat ttgtctctgc ttatacttct taacttatac
    41041 atttctgttg ctaatgttgt ggattctttt actgaggcat attttccaat ttgagcattt
    41101 agcatattga tttgattttg tgtagaattg ttgtctttag acttgctttt attattattt
    41161 tttttgccca cttattcacc tcatctctta ccaataaatc ataacagttt tttgattatt
    41221 tctatttttt cttttctctt tttcttccag ataatctgct aagaaattcg tataagccaa
    41281 actagaatat ctatcttttc ttgctccact tttttccttt attttaattt ttcctccatc
    41341 agcactatat tctaaattta ttaactcatt cactaaagcc gttgtttgaa gataaggggc
    41401 aatatatttt gcttctaatt ctgccttttt atctatttca tctgccttta tcatttcttt
    41461 ttctaatatc atttcttttg cttcaatatc acttatagga agttctaagg ttctatttgt
    41521 aaggacatct cttaaagaca tagccatttt atgattttca tcagcgtaag ctttcatgga
    41581 atatacaaca ggaagtgatt tttttgctag tgacttgtca acagtattat cttcattaaa
    41641 acatgtgtaa gcatcatacc attcatctct atctgaatca taatttgctt tctgtatata
    41701 gctccataca gttgttccta taccttgtgt atctaatatc atataatctg cctgaaaatc
    41761 tgaaaataat tgttttaatc ttattgcttg tttttcagct tccataccat tataagcttc
    41821 tatatggaca acacatcttt tatatgtgcc ttcatttgga agcatcctca tcaaagtata
    41881 aatagaatta tcattcttaa ctcctctggc caaagctata tctgcaccaa taatccgtat
    41941 ttctcctttt atcttattaa gatgatattt cttatctctt tttttcttat tttcaagata
    42001 ctctatatca ctaggaggat aaaacatact ttctaatacc ctacatggat tcacccaaga
    42061 tgacttgaag aaagcatcat ctgattcatt ataaaacact ccacaatact ccatcatgaa
    42121 agaagcatca ctcatactct cttttttcat ttctttaagt attctttttt tagttaatag
    42181 tccatgttct aaagagcaag tgaatggaat actacatgca aacatatctt caccactaag
    42241 catacctttt actgtttcca taaacttttt ataactccaa tgctgagaat accagcctga
    42301 actaagataa atttctttat tctcttcttg catatatcta tatttaggat tctgtaaata
    42361 ccctggttgt cttgggtttg ttaaaaatgg aactaaaaca tcattcacag ttccttcatc
    42421 caccattcta tattcatcaa caataagaac attagctctg taacctcttg catcatcatt
    42481 agatacaaca gcttctattc tacttccatt ccaaaaatct atagatactt cttgtgcatt
    42541 tacttggaaa cttttaattt ctcttttcag agtatctgat tttaaatata aatcacctaa
    42601 aattttactt gtaataagta attttgcttg tttctttctt tttgctgcta ttaaaacaca
    42661 agtacctggt tttaatacag ctataacaca acaaaacact cctagaagcc atgattttcc
    42721 cagtccacga gaagcaataa atacaaattg gtcagacttc atcatcatat aaattaatat
    42781 ctgttgaaat aaatgtagat taaatccaaa gtaatccata cagaatctat gtggatttgc
    42841 gagataaaaa gcaccccaat actctcctat actctctagt agatttcggg atgaatcatt
    42901 agatgacagc tctctttttt catatttagt cctcattttt attaccttct aaaatgtctc
    42961 ttacatcatc tttaaattta atatctttat cgccatcatt tatcgaatac ttacctgtag
    43021 ctaaacctaa tgcaacagca agtggttttt tcatatgttt atttacataa gcttcaaatc
    43081 catctacatc ttcatattcc tttaacctat cctttacagg ttgatttttt tcatatatca
    43141 tcattttcat tccaaatgta tcatcttgcg aatctccagc tttctttttc tgactaggct
    43201 ttatttcagc atcttgcatt ttacttgata ctaatttaga taaatcatta aaagctttca
    43261 tatctccctt ttctcttgat ttatcttttt ctaattcaat aatacaaatc tcttcaaaca
    43321 attttctttc agttaatgac tctggttcat aatattcttt atattcctta tattttcttt
    43381 ctaagatttt atactcataa tcatcaaaac ctcttcccca ttttaattta atttcatcat
    43441 ttatgactat atttttatca ttattatttc ctgtatatat ttctttcaat aaattatcta
    43501 aagatgtctt tcccttatat tttgaatttc tattaataat tttcatatat tcatctatta
    43561 attcatcttt atttttttta tctgcaagtt ctttagctaa tttttcatca aaataaacat
    43621 caaagttgaa acatatatgt tttagtgcct ttacaagttc tccattgtaa cacccattta
    43681 atagtaaaaa cctagctcta aaacattctt tgcatactgg aagtctttta tttaaagtaa
    43741 atatttcact atgacttttc caaaaatatc tatctgtata tttttcttca ccacaattca
    43801 aacactttgt tttactaatt gccattcata acatcaccac cattaaaaaa gaccactaga
    43861 gaattaaatc tctagtggtt aatagggaga ttcaactcaa ttaagagctg aattaaattt
    43921 acaatataaa cttaactcag ctcttaataa ataacttata gcttacttaa atttatattg
    43981 taagtacata ttctcccact ttcattaaat atcattaatt tttgcattgc gtgtgaactt
    44041 aatcttagat tcttagcata agaatccgtt ccggagaaac ttccatttac acatatttca
    44101 ctttctccat aattatcttc cttacaattg tgtagatgag ccataaagat ataatcagga
    44161 attaatttta taagagaggt cagtttagga attgctgtag acattttatc tttgtctcca
    44221 tgcactccaa aacaagtatt tccacatatt ttagccacta ttatgtcatt atcatatata
    44281 ttttcttgaa atataacatt gtttatattt ttaattctta gctttatata ttcatctatt
    44341 aataatgtaa aattatcttt atctaaattt tcatcttttt taggaagaac tctatcatgg
    44401 tttccaccta ctgaataaat aataatttta tcaatttctt tagataactc atatataaat
    44461 tcactaagta tttcagacac ctctataatt tgttcaacta tattttctct attttctaat
    44521 cttatagaat tatgtatgta tccagaaatt aaatctccaa gtaacattac atgcagtctc
    44581 ttaactttat gtaacttact atattcaata attttatctt ttaaatattg tattcttatc
    44641 ttgaatattt ttgaattata tctattaaat gcattaatag tctctaatcc ataatgtatg
    44701 tctgaaatta gcataatagc ctcttgattt gaagattcat agcatttgta actagaatca
    44761 cttagaaatg gcttatgaag tgatatatca tctattttat tattaaataa atcaattata
    44821 ttatctattc ttgaatattc tcttattttc ttatttacta atgacctttc atcagatagt
    44881 tgtactttta tcttttttaa ttctaatatt ttctcattta ttttatcaat ctcttcttga
    44941 gtagaattat tctgtatctt agaattaaga taatcaaaag cctctttcaa cccataggaa
    45001 accttcctac aatggtctgg agaacattct aaccccaata gttcaactat ctctccccaa
    45061 tccaaatcta tctctttatt aacctttgct agtcgtattc taatcctata gtcaactagt
    45121 gactcatctt cttttttctt caatatgtct tccatattta atatctccct atttatcaca
    45181 taaatatcat tatcaatgta ttaagtaaaa aataaatagt ccaatattga tttattggac
    45241 tattgtttca cttaatctta tcgttatgtt taaatctgta tcaccagtat acttatccaa
    45301 aacatcacta agtaatactt catggtctcc atctttcaaa tgttctataa ttttatatgt
    45361 attattttct tgttttatta tttcacattt ttctaatact gttcctttat tatttttcat
    45421 gcactttcac cttttttata attttattaa ctctactggg aatatattta tttgcaaatt
    45481 aggcagcctt gtagctaaca atagctaata taagttaacg catttagcat ttatcaagga
    45541 ttttctataa cttttttatt ttatttttac tattttaata atttaatctt ttatccttga
    45601 gattttatat ttgaattttt aactttaagc tttatatcta ttgttctctt ttatacagta
    45661 caatcgtttc gtttgtatgt acccatcact tttatataag cagtttgatt tttaacccaa
    45721 aaccaaatgg gaacttataa tttatgttat tcgcctaacc tgcaaattaa aaaatagtcc
    45781 aattaaggac tatcttaaat ctacatctat aattgtaagt gcatttgatg tactcaatgc
    45841 aaaatcaact tctttttcaa attcttctat ttcatccctt aatttttcta ttttctctct
    45901 tacttttaaa gggtctacta aagaccattc ttgttgtttt ttataaaatg aaataagttc
    45961 tgctccatct ttactttttt ctttttcctc aaacattctg tctgtatttt tttgcacttc
    46021 ttcatttcta cgatttactt cagacatcat acaatcatag ttactaacca tttgtctcaa
    46081 caaggattta tctaattcta tactattttt tctttttatt gcttctaaaa ctgtataatt
    46141 tttattacta atttgaacat ttgttatagc attagagata ttaattgctt tatctaatgc
    46201 gttataatta tatattaaat cttctatttg ttggtattta cttgaaactt ctacattaaa
    46261 atcttctaca cttgtttttg tttcatatac atttttatca gagccttttt tagtacctac
    46321 aattttaaaa ttactaatgc atctatctat cttatcttct aataacttct tttctgctaa
    46381 agctttatga acattatatt taaccataaa aacatctccc ttttaattaa gatattattt
    46441 aaaaataaca aacttttttt attggaagag aggaagggat ttgaaccctc gtatcaaatt
    46501 aattgaccta atagtttagc aaactatcct ctttaccact tgagtacctc tccatatttc
    46561 tataaattac aaacagcaag tcgagtatcc ctaccctcga ccatggtcaa gtgctgtatt
    46621 ttaaaactcc gacagctcgg atagcgtggc tgttttttca cactaaagaa tcttttttaa
    46681 ttgtccacta tttggtagaa catcaccact tttttataaa taaatctaca taaaaattac
    46741 ttagttcaaa agactatttg atttattcac aatttcttca gttttttatt agccaggttc
    46801 ttctgacaaa cacctcgact tgtttttggt tttttattag ccaggcacac caacaaactc
    46861 ctctaatttt aaaaagcaga agtagaatct gttacctcaa attctacttc tttattctta
    46921 cacctttaag gcatactagg gcattcaccg tatctatttc aagttatatg ttgctcgtca
    46981 acctcgtgta tatttgccac gctatattca ttttagcagc atcatcatct tatatttgta
    47041 aaatacctat taccagccac tagagcttct caaaatgagc tatctctgct aattgtatta
    47101 atttttagca tattctaggt ttgctaccat atgtcaccat atgaaagggc ttttaaccca
    47161 tacgctctct atataattgc atcttttaaa gatttagcta tttttaattt tggaactctt
    47221 ttttcctcag ttttccaagg ttttttagtt ccatctttaa gagttatttc tccttcttta
    47281 cctttttgta ttttagttag gtatttaact cccatcaacg tcaattcttc accatcttgt
    47341 agtacttcgt ttcttttttt ttctatcaca tcaagtatct ctcttactct tatctgtgat
    47401 acacctaatt cttctgctac ttcttttaaa aaatctactt ttttcatatc ttcttaatct
    47461 cccttttctt atataatttt catttgataa tagtaaggaa taattttatt atttttatta
    47521 accccttaca taagtaatat gttttaagcg accctttttt aaaccacttt tccccaccag
    47581 ctaattacag tttttacaat ttgagcgata tcccttttta ccatttttat caaacctaga
    47641 tagcaactta atttttccac atctgctaca ttttttatat tttcctttac aaacagatat
    47701 ataataataa ttttcttcat agtttttctc atatgcatct attattttgt tcactatttt
    47761 atttatttga ttatttattg cttgaggagt tatattcatt aaatttgaaa taaactctaa
    47821 tgatttatct tttctatata aatttaaaat atctttttgt actgtggtaa attcaatttt
    47881 agatataata ttatttaaat ccataactat acatgttaaa tcatcttgca aatcattacc
    47941 cttttgaatc cttaaaagct ctttaacatg tgatttatca aacatatcta aatagtccca
    48001 ttctgggctt cctgcatctg ctaatggtgc tttccatata attggtctct ctatagaatt
    48061 tttaacatca gtcatatcat tttttaatgc atttaaattt ttcctaacca ttctcttaag
    48121 ttttaactct tctttactta attgtttatg tcctaattct ttatatttag ctttatacca
    48181 ttcataagta tctgagtatg tttttataat tggatatttt ttaatatctt taggtttaac
    48241 ttttatatct tttatttttt tatagttttt aggtaattga aaaaatgcaa aggaattgtc
    48301 ttctaggaat ccatctttat tagaagtgtt tgaatttata tttccaccat ttgcaggtgc
    48361 tattttattt agaagtgctt cttcctgaca tgctctatta aataactctt ttgaattgta
    48421 tattcttatt ttagtttcct taggtttatc atctactgag agtatatagc tccccattat
    48481 ttctaatgtt tttgctatat tagaagtaga atatatactg tcatctttat ttaatatcaa
    48541 cttaattttc gatgtattat gatgtgtgta ctcccatgta ccattactat tactaaaagg
    48601 atttttaaca tttatatatt cgattggatt aatttgatta tagccacacc aagtaatgaa
    48661 tctattataa tccataacta cttcttctcc atcaatagta acataatata caccatcttt
    48721 atctaaagga ctatctgatg tttgctcaaa tatattttcc caaaatttat cattgaattg
    48781 ttttttttct tgatatttca ctctagtaat aatattctca tttctctttg taagagtatt
    48841 ataaaatgta tctatataat ttctatttga ctcttcaaac cacgtgtgtt ttacccctaa
    48901 tcgttcctct atgtatttaa ttctatcttt gctattgtct atgctataat ctaaattctt
    48961 tatgtaatct tgtgcagatt tgccatctat ttcttcataa aaattgttat tattatatat
    49021 caatattata cctcctttcc ttgcaatcca tcatcataat ctgtatcatc ataatcccat
    49081 agttcatcct taaaatcctc cttatgcctt tcatttacaa tatcatatga agacctttta
    49141 ctcatctctg tgtatgtatc tatcatttgt tcatattcct catttaatat ttgataccta
    49201 tttttatgta cgcctgtttt ctctgattca tctaaatctt ctaaatatat taattctatt
    49261 tttttctctt tcatacttct ccttttctat attataagat tttaaattaa ttttcttggt
    49321 cacatttctg tgccgttttt ttgccttttg gtcacatttc tgtgccaccc ctaaatttaa
    49381 ttttttaact gtttttccta tatttttgtt aatttttaca gttcattacc tcttattctt
    49441 agacagactt tctaaataca attaaaaaag cataaatcaa ttgttttctt tgctaaattt
    49501 aaattatttc ccttccatat tacacaagga tttataatga aatagtctgt atttttgtta
    49561 ttcccttcaa cgattacata tttaaaaaaa taatatttat catcttctac ctttatataa
    49621 aatctaagta attccttttt aaatttgttc atatcttgtt ttattgtact aatatttaat
    49681 aattgacaaa ttttatataa actaattttt tttatttttg aaatatctgt ttcatgaggg
    49741 tttaaacata agatattact ctcgaaatgt atatatggta tgagttgata tatataactt
    49801 aattgtttat gttgtcttgg tgtgcaatgt tcaaaaagaa atctactagt atttatatat
    49861 attcttgtat attctttatt ttcaaaatta ggaattcctt tagtaaaata ctttggattt
    49921 atataaaatt tattattaga ttcatataat aattcacatt tttttacgtc tgctaaaaaa
    49981 tttctaaatg ccctatcttt aagatttaat atttctctca tgttttttct atctatagga
    50041 atcatttctt taaactgaga atatctaacc aataaatttt cttctcctgt attatagttt
    50101 agatatgttg cgagatatat taatctactt atattagctt tacttatatt tacttcatta
    50161 aataataatt catttttaac ataagtacaa aatacaaaac ctcctaattt aaaattatgg
    50221 tatggtaatt cttttttatt attgataata gccctttgct ctggagaaaa actctttttt
    50281 ctctttccaa tttcaagtac ctcacctctt ttcatccctt tatgctccaa tatttctcct
    50341 gttcttttgt ctgttacaat aacatctttt ataaattcat tacctctaac tataaatatc
    50401 tacctctttt cttataaatt ttatttcaat tacaagataa aaatcatctt gcaattgttc
    50461 ttcgcaacat gttgcttcag aaatttcatt accctctatg ttctatttct attatatcat
    50521 ataccctcta tgttctcaat atttttttta atatctaccc aaaatttctt gagtagatat
    50581 tttcttttaa tctggcatat tattaaatat attcttaata ataggatttt ctctttttat
    50641 atcttttttt tcttcagtaa catttgtctt tttatttgtc ctatatacac cattgcctaa
    50701 acattgtttt aataatttat tttcttcttg aagatttttc cactctaata ttattctttc
    50761 caaagctgta tttctactgc ttatattttt atcattttga tacttttcta tttcaccaaa
    50821 tatatcttct tctaaataaa agctagatga ttttttcata taatatcact cctagaattg
    50881 ttccatacct acttcaaata atcctttagc tgtagccatt tgtgcatctt tagaaacttt
    50941 aaatctatta tcgaatgtca tatgtaatgc tgtacctcca cttacatata catccatttc
    51001 atctatgttc ttccatttag aagatattct ttgagctgtg ctttcagaag ccataatgta
    51061 agcaactttc ttaagttcat cataatcatt agaactatct atctcattaa gttctcttat
    51121 tattcctcta tcttttagtt gcttctgaac cattgttaaa gcatcttgat ttccagcttc
    51181 taatgtgtct gatagtttat cattaaatac aaaacctttt tcaaagaaag acatctcagt
    51241 acttctaaaa cctattgaaa ccatgccaac cgctttatct tcatttactt ttccttctaa
    51301 tgtatgaaat aatgcagcat ctccttctct aaaaattgat atatcagata tttttatttc
    51361 tttatgtcca ccttttattt tatcttttac tttaaatgtt ttacctttat atgtgtctac
    51421 aacttctttt aatgttgttt tcctaaatga tttatatgga acgcccatca tcaattttac
    51481 ttcatcagct acagctattt cattaagagc agcagcaact aatattctca ttgtaaaaga
    51541 tactttagaa tcatcagaat ttcttatagg tgttatactt tctttttctg ctaatgaacc
    51601 aacaaagtaa cttacacttt caaaatctat gtatattgga ttttcatatt tctcaaaatc
    51661 tatgtttctt ccatcaccaa atactgattt gaataaacat tctttaacca ttccattgta
    51721 cttactatat ccttttacgt atcctcttcc tatatctaag cctataactt ggtaattttc
    51781 ttccattttc attcctccta agtaaatatt tgctaaatat attataccat ataaaaactt
    51841 gataattaca ttaaatttgc acaaaaattc aactataaaa tgacattttt tagttattag
    51901 ttaaaattag cactaaatta gaactatata taatttaaat ttaaaccaat aatttattat
    51961 taaaaatttt tagttaatat ttaaattata tatcaactat ttccaaacca ataaatcaat
    52021 ttctttaact atactattta tgttttttta gatgtcaatt ttaattttaa gtaaaatatt
    52081 gaaacttatt ttcttacaga cgacattttc attctaattt aataaatctt cctatatttc
    52141 aagttatttt ttgtatttaa tatttttata tatattagtt gtttttatgt aatcaataca
    52201 tacactttta ttttatattt tccttgttaa gaatgtaatt taagagtaaa aatctaagaa
    52261 atatctttag ataaatattt gttttatgag gaaaatacag agctatttcg tctgtaaatc
    52321 cgtctgcaat ttttttgaaa tgtggaaatg aaaggactac acacaaaatc ctactgacaa
    52381 acaagccact ttccataaaa taccccctac ttcattttta tttattttaa tatgtaaaac
    52441 actctattta ctttatttaa ttaataaaag tattactttt atcttatttt aaaaatctat
    52501 gtttttgtca gcaaaaaatg gcataaaatt aagtatttta tgccattttt ctaaaaccta
    52561 gtattttaaa cacttacaac acctacacct tctattttgt cagtaaaatg tcagtcatta
    52621 taattcttag actacaaacc tgttgtaatc actgcatttc aatttttagt tattgatatc
    52681 tatataaaat attatttgct atagaataaa tttttttgtt atggattata aagtcttata
    52741 tacatcattt tagcattaat ctgacatcgt cgaatatcaa ctcacaacct cattgccata
    52801 tttttcttga caaatttgtc attattgtat ataatttaat taagataaga attaatctta
    52861 tctatacaat tcaatattag ggggtgacgt tatgagaata acaaaaggca aaataaaaga
    52921 gctaatcgag ttgtgccacc aacttgaaaa gctctttgta caagtattta aatcacttga
    52981 acatattttg atttctttat gttcttgtat cggttggtta ttaatactta tatacataat
    53041 taaacattaa taaccaatgc aatataccta taaaaatata tctctatagg tatattgtaa
    53101 cacacctaat attgaaagta aacgaggtga cgacatgagt caacatatta aaaacacttt
    53161 aaaaataata aagatactag gtttattatt cttcttatat tttgcactta gagcaatata
    53221 tattgtttat ctttaatatc tttattgagt tgcttaatgt ataagtaact cttttttgtt
    53281 ataatattaa tgaggtgata gcatgaaatt agaaaaatta attgatataa gaaaagaaaa
    53341 aaaatattct caagaggata ttgctagaat gttagacata tctttaagaa attatcacag
    53401 aaaagaaaaa ggagagaatc aatttacagt aagtgaacta gaaaaaatat gtagctattt
    53461 agatatagaa tcaaaagaac tacttgacat atagtaatat aatctactca aggtagtact
    53521 taacattaaa taaaataatt taataatata aaatagacta gctataatct agtctatttt
    53581 attataataa catattgtac aagccattta aatccattct aagcacattt caatgcactc
    53641 accttatgtt tataccttta atctttaaaa ttaaatataa aaataagcta gagtatatat
    53701 gtctagctta cagtagtttt tttaatgtgt ttatttgttc ttgaactatc gttttactct
    53761 tagtatctaa ctctctataa ttgtctaata gattgacttc ttcttctttt agttgtatat
    53821 tctcttttaa atctgtttta cacaatatat aatctatact tacattgtat atattagaca
    53881 actcaactaa tttatctata tctatttttc tattaccatt ttcccacctt aagacactat
    53941 tataagctac atttagttta tcggctattt cttgtatatt atagcctctt tcttttctaa
    54001 cttcttttag tctattcatt ttctcacctt cttttttaca tttataatat catataagat
    54061 aactttaaac aacaccaaaa aggttagtac tataaaacat tcaaaccctt ttcggtatta
    54121 ttttttattt tttatattga catacaccct ttttggttgt ataattgaat catagcaaag
    54181 gagaacaaga aaacacaaag ccacctctca aatgaagtaa caggcaaaga accttcttaa
    54241 aactctaaag ctaatatctt aaaggattct attaaaaaat attaaactac tattaaaaaa
    54301 ttactacctt taagttgacc ttttaaatgg tgtgaatggt gaaaggcaca caacacaaat
    54361 attacacata gttttttctt cattttttaa ctacaaaaat gaattagtca taccagttgg
    54421 tgaggtgttc ccaacattaa gtaattaaat aaataaaatt aataaaggtt tccaattaaa
    54481 gcctacaaaa aattgaggta tcaacttagt tgcttctata atggcactca atacaattta
    54541 atatgacata gcagttgtga ggtactgcgt tataaaaagt actaaagatt gagcattaaa
    54601 attatagttt gtactgcttg acacctacat ggttataaac tatctaatat ttactaaaat
    54661 tatttattat ttattagatt attttagtaa gtgttagaat acaacactta aattatgata
    54721 taataataaa ataggagtgt gaacggcatg gatgaaaaaa tattagaatt attacaaaaa
    54781 atggatacta gtattaatga tatacaagga gaaataaaat ggattaatac tagactagat
    54841 agtatggatg gtcgttttga tgggattgaa aaccaactta gtgatttaaa agaaggacaa
    54901 gaagaaatta aaaagaaact agacttaact tataatcaag ttgctagaaa tatggaaggt
    54961 ataacagaag ttggcgaaaa aatagacact ttaaaaaatg acatgaactt tgtagaaatg
    55021 gctacatcta aaaattggaa tgaaatagca aagttaaaat caattaaata ggagtagata
    55081 aaatggatga gaaaacatta gaattgctac gagaaataca ggaaagtatt aaaattttaa
    55141 atgacaaact tgacgaattt gattatacac aagataaaat aaaatctaat gttgagggac
    55201 ttttagaatg ttttagtcgt attgatttta gaattgaaga cctagaaaat ggtcaaacct
    55261 cattgtatac taagcttgat atagtgcaaa atgaaacagc aaaatcaatt aaatagcagt
    55321 acataaaaag acacttgaat tattgagtgt cttttctaca agctcttagt atggtattat
    55381 taaacaataa tatcattgga ggtataacga atgtatgagc agagaaaagc aaaagtaata
    55441 ttcaataaag gagctggtaa ttctagagga gaatcatata cgaatagggt tacaattcca
    55501 actacatgga taaaacatat ggacataact aaactagaca gggaagtttt gttgactttt
    55561 gatggtaata aaatagtaat agaaaaaata gatgagtaga taaaaaatct actcaaaaaa
    55621 atacttgaca actcgtgacg agtcgattat aattaaatca taaaataaaa ttttttacaa
    55681 aatgactagt aacgagtcag taaaaaggga ggatataaaa tgctaaatat atacataact
    55741 aacctaggaa aatataacga aggtgaacta ataggggaat gggctgaatt tccagtaaac
    55801 gaggaagaat tagaagaaat attagataga atagggataa atgaagaata tgaggagtat
    55861 ttcataacag attttgaaac agatatagaa gggttagaaa taagtgaaca tagcaatata
    55921 gagcaactaa atgaattagc aaaagagctt gaagagttag aagaatatga gattgaacaa
    55981 ttaaaggctt tacttggatg tggatacatt gatttttatg acatgcttga aggggatatt
    56041 tgcagattat caggtaatta tacttttata caacttgatg acaggtcacc attggatgat
    56101 gaaaatttag gacgtagtta catagaagaa atatgttgtg gtgatttatc ttgtatagaa
    56161 aatattgctt actactttga catagaagca ttttcaagag atttacgttt tgatagagat
    56221 atgattattg aaaatttata cgaagaagat atagaatatt atgaaaatat gacagatatt
    56281 gaatttgcag agaattatat tgaacgatta ggagatattg aagagttagg tcaagaaaca
    56341 cttgaaagat actttaatta tgagctatat ggaactgact tacgttatga gaatatttgt
    56401 atagcatcaa attatttagc tatagtttct taaataaaaa gttttagggc gttctttaaa
    56461 aacgccactt ccaataaaaa aattgaaagg ggaataaatc atgaaaaaat taataattaa
    56521 gataaaatca ttgtttaaaa aggatttaga tagtagctat tggagtacta cagaaagtat
    56581 tattttaaaa tgtggaaaca gcaatcaatt agaattattg gaacaagcta ataaattata
    56641 aggaggtaat aacatggtca attattctga atatatgaca cagatttaat aaatatatgt
    56701 gaccttttag aaggtgaaat aataggagaa gcaggaactt ataattcttt aagtactaga
    56761 ctaggaaatt taatcggatt agattgggct ttaaaaggag aagaattgag acagcaatta
    56821 atacaaaata ttaataatat gatgtattta gataatgaaa ataaaattca atataaagaa
    56881 ttttaagtaa aaaataatta atttatagga ggaaaataaa atgaataaaa taatcgtatt
    56941 ttatgatata gaagggcatc caggttttca agttcttgta agaaatgtaa aaaaatatac
    57001 tagacaaaat ataatatttg aattggtaga ggattatatt aaaaataata taggtgaaat
    57061 tgatttaaaa gatgaaaaaa tatatagtag tgtaagttgg aaggtttgga ctatatcaga
    57121 cgtagcgata tataatacct tatttgattt aagattagat tacaataaat taattgaaag
    57181 cgaagaagag gacactgata ataaggaatg tgtaaaagaa ttgttttgta tgggtaaagg
    57241 atgtaaatgg atggaaacag ttttattatt aagacaaaat aaaattgact cttctcaata
    57301 taatatttta acaataaata attatacata tgtcaaaaca tgggcagagc aatgcaaaaa
    57361 aatattattg gctaataact attctaaagt atttaaattt aatgagataa tgaaggattg
    57421 tgacaataat ttaattgggg atatatgttt taaatataat aacaaggaat ataagcataa
    57481 gtttacattt aatataaaaa aagataagtt agtaaatata gattgtgaat ataaaatacc
    57541 ttttttaaga tatgttttta atgatataga aaaattttta acaagatatt cagaaaatat
    57601 aagtaactta aaataacagg agggaaaata tgaataaaac aattgaaaac aatttaaata
    57661 tagagcttaa caatactata gaacacttaa taggaatagg tttttgagaa caaaaatatt
    57721 ataaaccaac tgtatggaaa tatgcaaatt tagtaatgca agaattatgc agtatggggc
    57781 ttacatatcc ttttgatttt ggaagaggta agggaaagta tcaaacaaat attgatgaag
    57841 agacaattta taaaagagct aaagaaaata caaagataca agaatatagt aaaaagtatt
    57901 taaactatat tgctaaaatt aaaaaaagta taagtaaata aaattcaact tttaatataa
    57961 ttggaggtaa taaaatgaaa aaaataataa atggatattc aatatataaa gatggaacat
    58021 ggtgcgaagt aataaaagaa ggaaaattta tctttgctgg ttctgtaaat gaaaaactat
    58081 catatgaaga tatatatata gctttaactg caaagttaga atttagatta catggtaagt
    58141 tactactttc atatagtctg tatggtacat ttcaagggga gaaacagtcc acattagaac
    58201 ttttagcata tgaaaataat tgtaatataa atgacattga agttaaacaa gttgttgaaa
    58261 atatacaata gtctgcaaat tcaaaaagga aacaaaatat taaatttaat agattacata
    58321 agttactatc attgtcgata taaagttata tattaattga taatgatagt aatttgataa
    58381 aacaaacata ttaggggagg tataaaaatg aaaaaaatag ctaatttgaa taaagaggaa
    58441 ttaaaaataa tatgggagaa aaatagtcaa ctaagggagg atgtaaggaa agcttgcgaa
    58501 gacaatgaca tgtattggat agatgaaata ttatgccatc ttaataaatc attagatgat
    58561 tggtctattg gattttacaa tgataattat ataaaaatag aggataatca taaattttta
    58621 ttagaactta aatctgtatg tgaaaaattt tcttttttat cagaagaaga acagagacct
    58681 ctcgagtatg cgatttcatt aattgataaa ttacattgta tggattttga aaataaaaga
    58741 tttaatatgt tggaaaataa aattaataat atggtcaaaa aacttgaaga aaaagtaatt
    58801 gaagaattta ataagatgac agagccattg gacaaagaat atttattaga aaattttatt
    58861 gaattttatg ttgaagccta tctcaatgat aatgaatttt atatagataa tgagtatgtg
    58921 ttatacgaaa aaattattaa aagttatgct taaaagaatg taattggagg gttttaaaat
    58981 gttagcaaat cagataaaag gtattaaaac atcacttgaa acaagcagct taagagaact
    59041 aaaaggatac ataaaagatt taagaaaagc actatcagga tataaatata agaataaaat
    59101 agatgaaatt acagaatatc aaatagataa attatgttac aaaattgata atacagatat
    59161 atttgacttg aaatataaag aaatagaaaa gtatatagat agtttaattt tgatacttga
    59221 ttttatcttt atggaaatgt aatcaaaaga atgattttaa tataactgga ggtttaagca
    59281 tgaatgagta tattttgata agttatacaa aaggcgaagg aacttgtgac cactgtggaa
    59341 gaactataaa aaatatagct acaataaaaa ataatgttac aggagaagtt tttcatgttg
    59401 gattaacatg tgtagaaaaa ataatgaaat tgaatgttac attttacaaa gcattgtcga
    59461 gagagataaa aaaacattac aaatgcatgg agtactacag taagggttta gatatagaga
    59521 caaatcttaa taaaatagtg aagaataata ctaaatacaa agaaggttct tatgcttata
    59581 aatctaatga acaaatgtta gaagatgcaa ttgcagaagt ggcttggtct ttggctcgta
    59641 tgatagatag ttgtatgaga atgaataaac ttagtaagtc tggattgata gatatagata
    59701 tattgaacag tttgtttatc aagtataagg aatatatgag taaatttgat gaaaattaca
    59761 ataaaaacaa atataaatat aaaagttgtt atactatgaa acctttaaaa gtaatattag
    59821 atgaaaatga agatttaaaa gaactatata aaagtatgca ataaatgtat gtaggcgatg
    59881 aattaatgac aatgaatttt atatagatga ggattatatt ttatataaaa gagtgtcata
    59941 tctttaatat aggacatgaa gtaataaaag agtttaaaat tatattttta atatgatata
    60001 tgagttatca aatcactatc attatagcta tattattata atttaaatga taatgatagt
    60061 gatttgataa aaaggtttta aagattgtaa aaatacatta agatgatttt caaacagctt
    60121 atagaggctt gtacggggtc ataattataa actaggagga tataaaaatg aaattcaaaa
    60181 atatagttat gggaatgtta ttaggtttaa tcattgtagg agtttcagga gtaacaaaag
    60241 ttaaggctgc tgaattagat aatttttata tagagtccac agatagagtt attgaagttt
    60301 tagaagatga aagtatagtt ttatatgata ctaaagagca agtttataat ttctatccaa
    60361 tttgtatggg agactggaac tatagcttta aaaataaaaa agatttagat agcgcagttg
    60421 caacttacaa agagctatca agtaatataa atcatttaag taatatatac gtggttaata
    60481 agttaaatga caatggaaac attaaagtat ttttaaatga tggaagttca attgtttata
    60541 taaaacagga taataaatat tacttttatc cttcttgtat gggtgactgg tacttaacat
    60601 tggatagtaa aatttattta actaattgta ttaatactta tatagaatat tattattcct
    60661 tgtcaactgg aggtggcaca aatgaataat aatgataagt tatctatatt aaatcaattg
    60721 gaatacatag aaaatgatat tgatgcaaga aatgaaatga ttgaaaaatt taaggactta
    60781 ttggtcaaat atccaaagag tagagatata agaagatata taaaacaaca aactcaattt
    60841 ttaaatggta ttagatatat atatgataat ttagatattt tgaagaatat gataaataat
    60901 gacaagaagt gagaacatta ctagacataa caatgtctac tgaatgtcaa agagattcat
    60961 ttagtaaata caaagttatt atgtcaattt ttaattaaat tgtaatttaa cataaaaatg
    61021 tagttactat tttaaaactc ataataacta catttaataa tttaaaaagg gagatggaaa
    61081 aagtgaataa attaaaagtt aaaggaaaac aaaaatttat gaatttagaa ataccagtta
    61141 tagaaggtgg ttttggtgaa gataaaaaat gtatgacgga taagactata tcagaaatac
    61201 ataatcagcc taattttaag ataagagaga gaataaagga taatataaaa agatttaaag
    61261 aagacataga ttatatagat ttaaaagtta tccgtgacac ggatgacaat ttagagctat
    61321 tacaaacact tggatatagt aaaatgcaaa tatcaaaagc tgataatata tttttattat
    61381 ctgaaagagg atattcaaaa ttaattaaga taatggatac tgatttagct tgggaaatac
    61441 acgataaaat aatggatgaa tattttagta tgagaaaaaa gttaaatgac ccttttgaaa
    61501 acttatctcc agagttaaaa gttataatca aactagaaca aagacaagca gaacttgaat
    61561 ctggtcaaca tgaattagag gaaaaagtta atgtcctata tgatttttct actatagact
    61621 acaatcaaca agaaactatt agaagtttgg taaatagaat ggtaatacaa gtatatcaat
    61681 gtttaaattt ttcagcttat gaagatgcta aattaagaaa aagagtatac ttttcactat
    61741 ggaaagatta tagaaaaaaa tttggtgtta atagctataa gaacactgct aaaaagaact
    61801 atgacaatgc aattaaattc atagaaaact gggagcctaa ttatgattta agcaatgaaa
    61861 tatacatgtt tcaaaaagtt gaaaatatat aagaataatg attggagatt attatgatat
    61921 gttatgtcaa agatatacat actataagcc tatatgatgc ttttagatgg catacaatgg
    61981 ggttgtcatt cattattaaa gatggtaaat taaaaggttt tacaatgtaa ctaattaatt
    62041 gagaagagaa ttatgataac attcttttct caattaatta tcattcctaa taaataaagt
    62101 tcaaaagata gtgtaaaaga taatacattt tgttaatatt agtaatataa aataaattta
    62161 aaaatggaga tgaatatatt gattgaaaat aagtttatag aaaaattaaa atataccaaa
    62221 aacataccaa actctttata caaagactta agacataatt ttttatttca ttcaaataaa
    62281 atagaaggaa gtacattcac aagtgaaagt ttacaagatt taattgagca caacattgta
    62341 aaaggtgacc atactttaga tgatgttata acaacagtaa attcaagcta tgtatttgaa
    62401 actgtaatag atacattggg cgaatactta actgaaaagt acataaagga tttacatgga
    62461 caacttatgt ataattcaaa tattcataat atggggctat ctggtatata caaaaaaata
    62521 ccaaatagaa taataggaac taatagtgta ttagcccaac catttgaagt agaaccaaag
    62581 atgttagaac ttattgagtg gtataataat ttaaaagata ttacattaaa agacttagca
    62641 gaatttcatt atagatttga aatcattcat ccttttcaag atggcaatgg aagaatagga
    62701 agatttatat tacttaaaca aatacttgag aataatttga aattgattat aatatcgagt
    62761 gatactgtag atgattatag acaggcttta aaaggttgtc ataatgaata ttataaacct
    62821 ttagagcaat attttgaaag tttagatgac tacaaagaaa aaaataaaga tttatggagt
    62881 ttttaaccta ataattaaac aaatgaatgg aagtgaaaac tatgctttac agaacggaag
    62941 atttaaatac ttttgcaggt attggaagtt ctaaaggtgt ttattgtcaa ctgccactac
    63001 cctaaagggt agtagcttgt aaaagctagt tgaatagcct aagtttacac tacgttatgt
    63061 aagaatatat agctacttta gaatacttta aacttaaagg aatattccac atattaaaat
    63121 actcttttta caaatttata attaaatcat aatctaactt tttatttgaa aaactttcaa
    63181 ttaaccttgc tttatcatta gcattcttta aaatgtagtt atttaaccaa taaactatcg
    63241 catcacccct ataatggagt ccaatttgga ctccattttc ataacaccaa aaaggatgct
    63301 catcttctgt attgtcaatc caaatatgaa attcgtttct aatttcatat ttttttaaac
    63361 taatttcatt aggaacatat atataatcag gactatagtt gccaccaaaa tttactttta
    63421 taaccataat tatagtctcc tttttaaata attataacat attttataaa aaactggtaa
    63481 ttacacttgt agtttaattc caaaatatag cattctacaa gtgtatctaa atttattaaa
    63541 gcaaaaatat aaaaaaataa aggatactat atatttaaat gcaataattt ttgtatttaa
    63601 atataaaaac tcatatattt atctataata ttatatctat taaattataa ataactaaag
    63661 ccaatataca taagaataac cacccaataa agctttcatt cttactttca aacatattta
    63721 aaaattttaa tgcatcttta aatatcaaaa tagatagttt tataattaca aaaactgcta
    63781 atagaataaa caatgtttta agcatatatt tctccttaat aaataattta aaatcttatt
    63841 taatataaat tttgtttaaa ttaatctgtt atttataaat aaattatatc aaagtttgtt
    63901 gcactttaga aatatatgta aataaaaact attagtcaac tggttaatat ggtatgacaa
    63961 caataatctc atgtagtata cttaatttag aggtgagtat atgacttgga atgatttaaa
    64021 aaacaatgat ataacatata tagttgaata tattaataat aagttaaata atagtaagag
    64081 tttgactaaa gttgctatag ggcttggtgt gtctgaaagt agcataagaa aataccttac
    64141 taaaagaggt tataaacgta taaatgatga gtatgtgttt attggtgaca atagtatgac
    64201 aaaagtagta aacaatagac aacagagtaa taatgataat acatttaata tgacaataga
    64261 agatgacaac aatcacaaca tagtaattga caaccaattt aaaaataata tagtctcttt
    64321 agcaaaagac tatgataaaa tacaagatgt attaaattgg tttgagaata aagaagatac
    64381 aaatgtaata gaagttgtac aggatggtat taagattgat ttacattcaa aagatgctat
    64441 aaggactaca gttaggttga ataaagatgc atggaattta tttgatgagt tttgtggaaa
    64501 attcagagag tttaataagt ctgatttaat gagtatggct ttattagaat acataaagaa
    64561 gtatgataaa taaaaatgac aataaaatcg tagttttaat ttaaataacc tcattatttt
    64621 gaggttattt tttttatttt ctatttaaaa cggagaaggt aaatgttata atatatatat
    64681 aattaaaaaa aggatgtttg aatttatgaa ttataattta aaaaatgaaa atgtattatc
    64741 agagctatta caaaatgagg atgaaaaaac aaggattggt atactcaaag tttataaagt
    64801 gttaatattt tggtttgcta aagaaggaaa gcttgttgag gaagaaaatg actatattgt
    64861 tgagatagta ggtaatgata aagaagaaat tgtgagagat atgagccaga ataaaacata
    64921 caatgccata atggctataa tttttaaaat taataagata tttaaaactt taaattacga
    64981 tattcacttt tctaaaccaa aaaatttagt cgctgaattt gatttatcaa aatatctaac
    65041 acaagatgaa gtacttcagg tatgtagtaa gctaactaat gcacaagata agtttataat
    65101 ttatgcagct ttttgtggtc ttattggtaa agatgctgaa gacctaaggg gtataaaaat
    65161 aaaagacata gatttagaaa aaagattaat aaagttaaag gatacagaat ttaagctgga
    65221 caagttctta tttgatttta caaaagatac attagaacaa aaagagtata aacaatattt
    65281 ggagcaagac agcaatgctg ctgaatttta tctatttaat tctaattctg aatatttaat
    65341 taaaactaaa ccagatgcta gatatggaaa tggattaaaa gagatgggat actcaacaat
    65401 tcgcaaaaga ttacttatta ttaatgatta tttagataat aaagtacagt tgaatttcac
    65461 caatttaaaa atttctggta ttatgcatca aatgcatcta aatgaaaaaa aatatactca
    65521 atctggatat tggactaaca aaagcttgaa agagtttaag gaggataaca atttaaactt
    65581 caaaatacaa gaagttctat ctatttataa gcaaaaatat attaaggagt aaccttatga
    65641 gtaaagatgt taaagaaaac ataagtaatg aacaaaaaga tttaaataaa ataaatttaa
    65701 tctatcatat tatatatgac aatgatagat ttaaaatgat aacaagaaaa tattttgaaa
    65761 tttttagatt aaagggtatg tctgctgaag aaataagttt aaaatttgaa gaatttctat
    65821 attctcttat ttcagataag tttaaaaaga taaatacagt aaatgatgtt aaaaaattaa
    65881 gaaatcaaga gaactcatca tcattaaaac ttaagaagag atggtctgat atgactttag
    65941 attctctaag tgaagatact aaatcttcaa gaaaaaaaag cagtaaatac ctaaaaaaag
    66001 aattagaaat tgttgaaagt gaatatttaa aaaatggaag aatcattagt gctggagtaa
    66061 aaaatccaaa agaattaaag gagcaaagaa aagatttttt agatgagtgg aagtcaagct
    66121 ctagttataa catatgtgat tacccatatt tacaagagtt aagtactagc aaaataaatt
    66181 ccgcatttat acatgatata ctaatgtgta taacagaagt actaaaagat gattatgatt
    66241 ttgatattaa taaaattgca atcaaaactc caccacatat ttcacctgga atttttttac
    66301 ctttcacaaa aggtaaaaga tactcgcact tgaatgttaa aaaaaatgaa aatgaataca
    66361 tgtcagacga ctatagtgct aagaatcttt caggtaaaca aatgaatttt ttctataagt
    66421 tttcaattgg gcaagatgaa aatattgaaa atcttaaact agagctaata aatcctgata
    66481 cagaaaaaag ggctttgcca aaaatatatt tagataaaca agaccttgaa attattagat
    66541 ttgtttatac ttatagccac atgaactctt tttcatttta tttaggcgat ttagtaaagt
    66601 acttaggact ttcagatgga aaaaagaact atattaatat caaaaataga ctcttaaaat
    66661 taccttatta tactttttat tcgaatcaaa ctaatgataa aggcgaatta aagtatgaga
    66721 ttagttttaa tttgttttct agtacaacaa tagtaaatga tgaaaacaat aataatagag
    66781 agttggttaa aatcacaaaa tcttttattg aagaagtcga aagagttaat acagatataa
    66841 tgtatagaaa tgaacttgaa aaattacaat taacacagtc aattaatcta gcttatttct
    66901 tagagggtag aaggtctttt cttatatctt gtggtgagga tataaaaaat aaaagtttta
    66961 gatatgacat agaagattta aaatttgatg ttcatcttaa taaaagtaaa acagtaaagc
    67021 aaaatatgga gtatttagaa ctaggtttta atgagataaa agaaaatcaa tttataatta
    67081 aagactataa aagaggaaat tcttattttg atgtttattt ctatgaagat tttgaaaaaa
    67141 gaaaacgtct tataaataat actatacttt ctttacctga ctacatgata gaaaataaat
    67201 cttaaaaatg gccatatatt ctccgtactt aacaaaaaat gtcgaattta ttttaaataa
    67261 acttaataaa aaaagtaaaa tgaccgtata ttctccgtac ttaacaaaaa atagattttt
    67321 caaaaaaact aaatgaccgt atatcttccg tacttaacaa aaaatagacc tttttttaat
    67381 tatttccttg tcgaaaaatt ttttttgtaa catatttttt acttttctta gtaatttcaa
    67441 atctcacgtc ttctgaaatc actatgtctg agctaaatga ccgtatcagc tccgtactta
    67501 acagaagacg ttgaaaccac tctatttgag ctaaatgacc gtatcagctc cgtacttaac
    67561 aaatatagac ataaatttat tttttgggta agataaattt gagtaaaagg aatcatcacc
    67621 aaaatggcta tatcagctcc gtacttctga aattattgat ttttcaaagg agaaaattat
    67681 gagtcttaaa tataaagata aagaatttgt acttgtagaa aaaaagaata taaatgaatt
    67741 agataactct aatataaaat atattgacct aaaggacaag cagtattatg tggttacaca
    67801 aggcaaaaaa cctaaaagat ttaacctaga agatattaaa aatataaaaa aagatttaga
    67861 taatggcata agtttaagaa agtgtgcaac aaaatggaac tgtagcacta ggactataca
    67921 ggatataaaa aataatattt attaatatac agaggtattt atttacttta tacctcatta
    67981 agattataat aatcatatat agagaaagga ggattataaa atgcaagaat taaaaccagt
    68041 tgctagaata tcaaagtcaa aactaaaaga tatattagat gtttttaaaa cttctataag
    68101 aaaagtagaa aaaatagatt attctgcttg taattcttgt gcaataaaaa ataatccttc
    68161 ttttgatagt cataaattaa atgaattttg ttcaaattgt cctaaattaa aaactatatc
    68221 agagttttct tatgttacag aaaaggaaac agaactaggt acaatagaaa ttgtaactaa
    68281 tgaaagtaaa tgtatggctt taagtaaaag tgctataaaa cagtatttag catatcattt
    68341 tatagtatct aataaaaatt atgttagaaa agcagtatcc ttccaaaata tagccgatat
    68401 atgcaatgtt tccattgtta cagccagaca taaccataat gtattactac gagttggatt
    68461 agtttattct acagaaataa aaagaggtaa atttgatata gtcatagatg aagagtacaa
    68521 aaaccatctt aaaaaagaag atggtggaaa aggttactta actatgtcat tagatacttt
    68581 aaatcactta ttaagttttg aaaatgtaaa tgagttaaaa cttgaaatta aaaaattaat
    68641 ttgggctgat gctaaaggaa gtaagttagg taaaagaata cgatttaaaa aagacaatct
    68701 tatttctata cttccagaat acataaagaa atcaaacaag cgtacagaag cctttttaag
    68761 aagttctaaa actttatttg atgtaagtaa tgacacaata gatacaaagc gttacgagac
    68821 gaaagaaact atctcagaga aatatacaga accaattaga atacaaatat cgaaattctt
    68881 tgataatact ggttgctctt tgagttctaa ttatagtaaa gtgttatctc agataaattt
    68941 agatagatat aatttatttg aagaagattt aagaagtaaa ttagacatgg aaaaagatat
    69001 tattataaat gacttagttg gattgtcggt gcagtatgga gttactagag ttttagcagc
    69061 attagattat atgtttaata aatatacagt tgatgaagaa gatataaatt ataatgaaat
    69121 acgtaatcct ggtgcattta taagaacatt gattgttcag agcataaata aaaatggaag
    69181 tttagcaata gcaatttaat atatggagta gttcaaaaaa aatgattttg gctactccta
    69241 ttagtgtttg tattcaaatt ataaaatact taaatagagc tataaagagc gtgaaatctc
    69301 tattagctct atttttttat gcctatttta atgaaattat atacacaata gaaagttttt
    69361 tatacatatt actaatttaa ttttccaata ataatatata tttattcaat ttattaagaa
    69421 acttattaaa aaaaaataat aatacatcaa caatatatta ttattaaaat ttatatttta
    69481 ttgtattcat tgtaattact ttgatgtata gttttttctt attttctaat tattgaattt
    69541 aatttttgta ttaattgcta ttaataattt ctgtattaaa ctaatgagta agttataact
    69601 atgaaactta tcttacaaag ttaataaata tatattgcat taagtaataa tataattaca
    69661 ttcaaagcgt tatataaata tatattattt aatacttcat atcttatata tgttatcatt
    69721 tttatttacc ttatttttac aaattattcc ataagtatat tataattatc ttgagggaaa
    69781 taatcatata gagggagaaa ttagaaaatg gatagatttg aagtattaaa atatctaaaa
    69841 tttaatgttt ggcattcaga atggccatta gagcttctca aaggggctat aacaaaggat
    69901 aatgctactg gtaatttatt attacaatta aaaatgtgta atatatctga taaggagata
    69961 aagtctgcat attttacaat agaatgtttt aatgatgcag gagatttaat agataataat
    70021 ttaaagtatg tttatcaaga tataaacatt aaaccacatg aatgtcttgg tgatgatatt
    70081 gctataaaaa taaatgataa taaaacaaga gcaataaata ttatattaga acaagtagta
    70141 ttttcagatg ataaagttca taaatatgaa agagaagaag gtttaattat acctaaatta
    70201 gataaaatag aattgttaaa tatagaatta ttagaagaac ttaaaaaaga ttatgaagaa
    70261 tatgattttc aatatgaaat taagtacatg cctaatataa tagaaaaaaa agcatggagc
    70321 tgttgttgtg gaaaaataaa taaattagaa aaagataagt gtgataattg taagagaagt
    70381 aaaatactgc aaataaaaaa gataaataaa aattatttag aatctattta taaaaaaagc
    70441 ctaaaaaaga aaaaagaaat agaaataaag cttgaaaaag ataatagaca taaattaaag
    70501 aacataaata aaaataatag aagaacatca atattattaa taagtatatt attgattttt
    70561 attattttta ttggtaaaaa tattattaat aagcatgctt ttttagatga aataaagtat
    70621 aaaaatgaat atagtaaaaa aatatctgta gaaaaagata atgtatatat gttaaaaaat
    70681 aatggaaaag taacacatag aaaagtgaat ggtgaaagta gttctatacc tggttgggaa
    70741 aatataatat ctatagcatc atatgataac tcaataatag gaataaaaaa agatggtaca
    70801 gttgtttcta aaggacttgg aaattcagat tcagacaata ttagtaaatg gagagatata
    70861 atagatatag aatgtgatag tggaactttt ataggattaa aaaaggatgg tactgtcgtt
    70921 gctactggaa ataatgatta tggtcaatgc aatgtgaata attggtttga tgtagtaagt
    70981 atagaaataa caaaatcaac cattgagtat atgaaaaata caacagtaat aggcataaaa
    71041 aaagatggaa aagtattact tacaggatat gatagtctga atcatagaaa agaaacagac
    71101 aaatggagag atatatcaaa gataaaatgt gggtcttatg gcatatttgg aataaagaat
    71161 aatggcacag tagttgtatc aggtagtgct tatgatatta agaattggaa agatatagtg
    71221 gatatacata ttggattatg tggaatagtg ggtattaaaa gagatgggac aataataagc
    71281 acagatgaaa agtttaatga aatcattaaa aattggaagg atattatttc tgctgaaata
    71341 atagataatc atgaaggaat ttctattgta ggaattaatt caaatggaga tattttaaca
    71401 tctagtagag gtcagaattt ggataatata aaaagattag aagatgtaga atatataaat
    71461 tttgatgact cgattgataa ttttttagta ggtataagaa aagataatgt aatttttata
    71521 agaggaataa acaatactat aaatgaagaa tacaacgaag aaatataaaa ataaatattt
    71581 taatttggag gaatagaaaa tatgaaaaat tacatagcaa gatgtttatc aaatatggga
    71641 gtattgttgg caggtataca agtattagcg ggtataataa tcatgtgtca aaaagtagaa
    71701 gttccatatg attatttgtc agatacttat gaacaatata gtcctattat gattggtatt
    71761 ggtgctgggg ttatagtaag tggaatcgtt atatgtttag ttttaaaggg attagcagag
    71821 ttagttgaaa attcagctga ccaaacacaa tatcaaaaag aaatattaat gttgttgaaa
    71881 aataataatg taaatgaaaa aattaatgag gttaaaattg aacaacaatt tacaaatgag
    71941 gaattaccaa aattataaaa tgttttaaat tatatactaa tactcagtac taattaaagt
    72001 actgagtatt tttatgtaac agtaaattat attaatataa aaatatattc tacatacata
    72061 aaatgataaa ataaccattt ataatacatt aaattacatt aaatcaaaaa agtatatgtc
    72121 gaaaacatat aatattaaat aaatatatac tttaaggagt gatttaatga ttataactat
    72181 ttgcgaaaat gatgatatgc aaagagatat catctatgat tttgttaaga tatttttaac
    72241 taaaatcaag gtaaaacatt atgacatttt aatgtttaag aatggggaag aactgttaga
    72301 agaatatcca aacaaagtgg atttaatttt aatggatata aatttaggag gtagaaatgg
    72361 atttgatatt tcaaaagata ttagaaaatt tgataaagat gcaagaataa tttttgtaac
    72421 tgtatcagag aaatatgcta tcaaatgtta tgagataaat gcatttagat atatgataaa
    72481 accgatatat tataaagaat ttgaaaaata tatgcttgac tttgcaattg attggagaaa
    72541 aagagaagct attattacta taaaaagaaa aaaacaaata ataaaaatag aggaacataa
    72601 tattttattt gttgaaatag tgaatagaaa attaagagtt gttactaaaa atgaagaaca
    72661 tataataaat gataaaatgg atatgtttga agaaaagtta aaagaggata tattttttag
    72721 atgccataag agctatctta taaatttact tgaggtaact aatttcaatt ataatttcgt
    72781 ttatttaaca agtgagaaaa taaaaattaa agtagctcct aaaaagacca aaaaacttaa
    72841 agagaaatta gcaaattttt ttagggaaat aatatggtaa attaaagaaa aatttctata
    72901 atcgaatata tgttcttgat aaaagtatgt gtacaagata taatattatt agtaggaaaa
    72961 taggaaaaat attaatattt ttgaacattt tgacattaat tgtgatttta gtgttgaatt
    73021 tctgttaaaa aaatcttatt atttaatcat agaaatctac tgttatagag tagaagattg
    73081 ttaattataa atgattttaa attatctgag ataaaatttt ttgtttctga aaagaacgaa
    73141 tgttcgaatg aggtgtagag tgagaggatg tttattaaaa gatattagat tatcttactt
    73201 aattcataat gcatatatgg gggttctata ataatgaaaa aacaagtcac aaaagaaata
    73261 cttaaaatgc tagaaaaaat ggatttatct tatttactca taattaaaag ttttgtatct
    73321 aaattaaaat agcccttatt gggctattta ctaagtttat caattacttt ctgtatgact
    73381 tctctttcat catcagtaag ttcagcaaat gttaagaata ctttttttaa aaattcatca
    73441 ttacttgaga atgttttacc catcattgct gctaattcaa tatcatctat atttttaaac
    73501 atttctccat ttccatttcg taaccagtcc tcatttacat taaaaacttc acatatctga
    73561 aatataaatc tatctgttag ctttctttct cctttttcaa gtctagaaat agttgcatca
    73621 cttactaata atttttctgc aaattctttt tgtgagagac ctaatttaat tcttaattcc
    73681 tttaaattct cattcatatt tacacctcct attatatagt atattaataa aaattgacaa
    73741 tgtcaataaa ataggaatga taaattgcaa aaagcaaaaa aaataattga caaatacaga
    73801 atgtggtact acaatgtaaa tatacaaaac gcaattaata atttgacaaa cgcaaataaa
    73861 taaggaggta gattatttgt ataataataa tgataaaaaa ttaataaatt tatttgaatc
    73921 atttaaaaaa atagactata cagaacaaag tttagtgtat tttttatctt taagctttat
    73981 agtaaacaga aaatgtcata aagatgcaaa tttgtatagt aggagaggtg aatgtaatta
    74041 tgaataattt aaatatcaaa ggaaaacaaa aatttatgga tttagaaata cctattatag
    74101 aaggaggttt tggagagggt aaaaaatgta taacagataa aactatatca gaaatacaca
    74161 atatggagat aaaacatgtt agagaattaa taaataggaa cataagaaga tttataaatg
    74221 ctattgattt tatagattta aaagtggtcg ttgataacga ctacaattta gaagtattgg
    74281 agttgcttag ttatagaaaa atgcaaatat caaaagcaaa taatatttat cttttatctg
    74341 aaagaggata ttcaaaatta attaagataa tggatactga tttagcttgg gagatacacg
    74401 ataaaataat ggatgaatac ttcaatatga gagaacaact catagatagt tatatgatac
    74461 aagattctat tgaaagagct aaaagatgga tagaagaaga aaaagaaaga ttattactta
    74521 aagaaacaat tcaagttcaa caacctaaag tagaatatca tgataaagta ttaaatcctg
    74581 acaaattagt tacgacaaca gatattgcga aagatttagg aatgacagca caagcattaa
    74641 ataaattact acatttaaac agaattatat atccagaaag aataaatggt cgaataaaat
    74701 gttggaaacc atataaaaat tatttatggt tgatacctga atatgcagat tttaaaataa
    74761 cagaacatga tacgcagctt aaatggactg agataggtag aaaatggtta atagaatttg
    74821 tagagaacat taaaaaaata agttaaatca agaagttaaa atgtaccttg aaaagtagat
    74881 atttaaaaat ataaaagata ggtgattaaa tgataaaaca aatactaaat aaaagaggta
    74941 gtctattaaa tctagcaagt gagtatttga cagaacaaga ctacctcaag tttcaaggat
    75001 ggtatacaca tagatatagt aagctggatg cttatgatgc ttctataaat gaatatttaa
    75061 attataaaaa cgacaaaaaa ttaataactt atgtatttaa tttaaaattt caagaagctc
    75121 tcatagaaat ataatattac taaacatggt gattgaaatg aattataatt atgtaactaa
    75181 aattgacttg aaatatggaa atacacaatt tgggtttgag aaatatagcg atgctttaga
    75241 taagtacaga gaacttaaag aagaatttaa gtatgttcca tgtattataa aacttcattc
    75301 atatgtagcg caccaagatt tatatgtgaa agaaattaaa gctgatggtt ttgaaaagaa
    75361 atatttagat attaaaaatt taataaaatt gtttaaagaa cataaacaaa atatatcaga
    75421 tgaactaagt ctttgtgata agaaaaagga agaagtatta catgtaatag aagaaatgaa
    75481 tttagacaca gcttctttaa atgataagat tgataccatt aaagaattaa aaaacacttt
    75541 agttaagaga aggttggtta aatatgaact aaataaatac tttgcctttt gtaatacatt
    75601 atatgaaatt gaagaagagt taaaaaaata tgaatctaaa tataaacaaa aagaaaatca
    75661 aggaaaaagc agattcaaaa aaaataaaaa ataggtgatt agatggaaga atatcatttt
    75721 aacttaataa aaaagctttg tgctgaaaga aaaatacaca aaggttggtt tagaaatatt
    75781 gaaaaatgtg gttgtggagg taaatgtaat aagaaaaatt gtaagatgtt agaaaaatta
    75841 taaggagata catatggaaa atcaaattga attaacagaa aaagatatag agaacacttt
    75901 aagtgcttta aatattatta aatatatttg tataaaatct aaacattgca aaaattgtcc
    75961 tcttggatat atgaaaaatc ttgatgaaca taattgtatg ctatatgaat taatagacaa
    76021 gggtttactt ccatgtgatt ggtctgtaaa aaaagttaca agattgttag atacgacaga
    76081 agaataaaac aaaggagctg gttaagtgga gttagatttc agaatttgga atggatttag
    76141 aatgatacat ggagaagaat taagattact aacagaagag atgtttataa aaagtggata
    76201 ttctgaacaa tactataacg atatttgtat accaagagta gaagatttga aaataatgca
    76261 atacataggg ctaaaaaatt gttttgaaaa aaagatattt caatatgata ttgttaaatt
    76321 tatctttgat ggtgtttgga aagtatgttt agtaaattta tctttgccaa aaggagcaac
    76381 agttacattt gaaagcatag gtggaaaata tacttttaat ttaagtgaaa tattttcaaa
    76441 agataggaaa ttagaaatca taggtaattt ttatgaaaat aaagatgtaa tcaaaaaata
    76501 taatcttagt attgaatagg agaagaaaat ggatgaaatg ataattaggg tgaaaatggg
    76561 agaaccatta ccaacactag gaaagataat caaatgtact acatgtttaa ctaatgaaga
    76621 gaaatgtttt aaggttaata agatatgtaa attaagttgg attaacgata ggaatagtga
    76681 agggttaatt gtagaatgca aaggtaaata tattaaatat taataagaat aatgaagtta
    76741 aaatcaagat tttaatagaa aaggagtgat taaaaatgaa gaaaaatcca ataaaaatta
    76801 aaaaatgtga ctgtggtgga gatatatatg aacttaatac acaattaggc actatgtatc
    76861 aatgtaaaag ttgtggcgag atgtatagat agtgctgaaa tattagctaa agaagatgag
    76921 gtgaagtcaa tgagtaaaaa agataagtta tctattttta taagtttaat attaagacat
    76981 aaaccagaaa ctattggaat taaattagat gactatggat atgcagatgt taatgaattg
    77041 attgaaaaaa taaataatac tggtagaaat attaatatag aaatccttga gcaaatagtt
    77101 aaagaagata ataagcagag gtacagtttt aatgatgata gaagcaagat tagagcaaat
    77161 caaggacatt caattaatgt tgaggttgaa ttgaaagaat tagaaccgcc aaaatgtctt
    77221 tatcatggaa cggctactag atttttagag aatattaaaa aggaaggtat tattagacaa
    77281 agtagactgt atgtacactt atcaaatgat atagatacgg ctgttaaggt tgggaaaagg
    77341 catggtgtac ctgtagtttt aaaaattaat acaggaaaaa tgtatgaaaa tggttataaa
    77401 ttttatttat ctgaaaataa tatttggtta tgtaagtata taccatttga atatgtagag
    77461 aaaataagta gagtagttaa ataaaattat agaaaatagg aggttattga atggatttca
    77521 attttagaaa gatttgtgaa aaagatgaac ttactgatga ttttattata aaaatttgcc
    77581 agttgtcaca tgaggagttt ggaggcacta tttatgtacc atgtaatatt catccatgtg
    77641 ggtgggatga gttggaagtt ccgaatccaa aggatttaga ttcagataaa ttaatggaag
    77701 aatttttatt agaatataaa tttgaatgtg aaaatatttc gagcaatatt tatgatagtg
    77761 accatccatt tataggcaaa acattgagag agattcttat gatagtggat tgtagattca
    77821 taattggtgt tatataagga gggtattaaa tatggaaaat atagaattaa cacctagaga
    77881 ttattttgag gatataaaaa ataaaaagca aaaaaataca aatgaaaatc ttgatatagt
    77941 atatgaaaac tctttgattc ttttaaacaa atatattgta actggtcaaa aaaagggtgc
    78001 taagaaatta atgtttttac ttgaatgtat tgaaaaagaa agaaatgtaa tagagctggg
    78061 aatagataca tttgtgtata aagaagatat agaaaaatat attgatgata tatctaaaaa
    78121 tacagtaaaa ataatagaac ttgaaaatta tgaaagagaa ataccagatg aaatagtaga
    78181 aataatagaa aaaacaaaag atatatttga taaaatgtat gttttgttta ctgattatac
    78241 aggtaaaatt acaaaggaga taagcaaaga gagaagagat aaagacccaa tattatttgg
    78301 tgttttttca gatgagaaaa gcagagctat tgtagataga ttttattatc ttggagattg
    78361 ggaggatgag tattgtgatt taacattaga gaaaatgata aatgattata agaaaaaagg
    78421 aagacaagac atattaaaac atataattac acctaaatca ttagatgagt taaaaaaaga
    78481 attagattct ttagaaaaaa ataatgatac atataagcaa gttgccaata taaagccatt
    78541 acctactaca aaaaactcta gtgtagaacc acctaaatta aatatattta aaaaaataaa
    78601 aaatagagtg tttaaaaatg aaaagtaatg ttgatttaac agagaatagg gattttagag
    78661 atgtaagagg aagaggcatc aatattttag gtatcgaaga tgcgccaaat agaatgttga
    78721 gttttagtga ttttggaatt ggacgtcttt atggtaaaaa tttagaattt gaatttaata
    78781 aaaatgaagt atttttaact ggaaatgcta atgacagaga agaaaaaaag tttcttatcc
    78841 tttgtgaaga aaataaggtt tgtgttagat gtggtgatga attaagagag gggtgggata
    78901 aagtaagcat agaactatgt aatgaatgtt atgaaatgtt agatgttgag tataaaaata
    78961 aaaagataat tagagaatta ttttttagag atagagatgt aaatatagag ttactttaaa
    79021 aaatatataa gaaaaataag tagaggagga atttatatga aagatgtttg attatatagc
    79081 tgggatgatg agtgctttgg aagtgatgaa tacgaaagta gagaggaagc tattcaagga
    79141 gctaataaaa ctagtatttt tagtgatgac aacagtatga caagaataat gagaatataa
    79201 aggagtgatg tttattaaaa gttttagatg tatattcaga cataagtttt caaggataaa
    79261 agattgtcaa ttaattacaa caaggagtca gcaatatacc tgtaaaattt ggatgtgtaa
    79321 atattgtgga caaattgtag ctggttcaac tcctgtttat catcctaata tgaaagtcaa
    79381 tgagtattgt gtaaagtgtg agttttcggc atgtgcaaat aattatgagg gatattgtaa
    79441 ctctaaagat aaagaaattg aatttaagtc tatttgctta aaaggtaata aagagatttt
    79501 gcagtgtaaa aattttgatt tggaataaaa tttagcttaa gtaggagaat tttagaatat
    79561 gaaaataaat gtacatgtta aaactaataa aattggttca gactgtgagc tggagtttga
    79621 aatagatgat gatgatttaa aagatatgtc tgatgaagag agagagggtt atatagataa
    79681 aattgcatgg gattatgttt ttgaaaattt tatagattgg aattggtatg aggttgaaga
    79741 ttaagttaaa acatttgttt taatgtgatt ttacctagta gatacaagga ggtttttaat
    79801 gaaagagctt ttagaagtaa aaaaaatatt tgatagttta gcatctacat ctagtagaaa
    79861 agaaaaagag agaatattag aaaaatataa aaataataga atgtttgttg aatgtttaca
    79921 atttctacta gattcaaata ttctcactgg aatatctaag aataaaatat gtaagaattt
    79981 aaataatact ggtcataatg aattagagaa catatatgat atgcttgact atttaattaa
    80041 gaataatact ggcagaaata tagatgtaaa aacaatacaa gtatttgcca gtaaagatga
    80101 aaaattaaaa gattttattt ttaatttagc tacaaaatca attaaattag gaataacata
    80161 taagactgta gacaaaataa tgccaggttt aattatctaa taaattttgt attttttaca
    80221 aaaaactatt gagaacatag aggttatatg atataataaa aatatattga gaacagagaa
    80281 gttaaaaagg gggggcaatg agatgactga caaaataata atagcaagtg tagatggaga
    80341 ggaaatgata tttagaactg aaatgaaaaa gttagaaaaa ggagatagtc ttatagtttc
    80401 tgtaaatggt gtaaaaagat tagctctatt cattaggtat ataagtactt gtgaagaata
    80461 tatagaagat atagcatttc aaaaagtaga tgaaatatta tatgaaaaca caattgccaa
    80521 agaaaaagaa agagttaaaa aggtatttaa agataagtgt atgaaaaatt ataaacctat
    80581 tgttaataca gaaatagact cttatttgag agaatgtggt ttcaattgtg atggtagaca
    80641 atttttcaaa agtatagaca atacacaaat tttaattagc agggattgtg ataaagatgt
    80701 tttgactgta tcgaaaggtt tgacaataac taaaacagat ataacaaata aaaatttaat
    80761 tacagttatt aaaataataa ataatagtct attaatagtt aggtaataga aataaatatt
    80821 gaacttttaa taagaaaaaa gattttaaat aaaaggagtg atttaatgaa gaatgttatt
    80881 aaaagagatg ggaggatagt tccctttgat gaaaagaaaa taataaatgc aatagaaaaa
    80941 agctttttat cattaaggaa caaaggaaaa agtgaagtat ttgatagaga attagcaaca
    81001 ctaatagcta aaaaaataaa aaataaacca tgtgaaaaaa tgcatataga agatatacaa
    81061 gatataatcg aatttagctt aatggctagt aaaaagaaag atgtcgctaa agaatatata
    81121 acatacagag agaaaagaaa tatagcaaga ggaagaaaaa cttataatga ttatatgtct
    81181 attgtaaata ctgaaagtaa tgatataact aaagaaaatg caaatatgaa cgcagatact
    81241 ccagcaggta tgatgatgaa gtttgcaagt gaagctacta aaacttttac tgaccatgta
    81301 cttttatctg aagaagcaaa agaagcaatg atggataatt atatacatat acatgataaa
    81361 gactattatc ctacgaaatc attgacttgt atccaacatc ctttagataa aatttttaat
    81421 aatggtttta gagcgggaca tggctctagt agacctacta aaagaataga gacttcaagt
    81481 atattaggat gtattagttt agagactgta caaaatgaaa tgcatggagg acaggcgata
    81541 ccagcttttg atttttataa tgctccgagt gtaagaaaaa catttataga agaaataaaa
    81601 aatatagaaa taaaggatga tattgattta tctcatttat acaatataga aatagaggat
    81661 tatataatta aggacttaaa agaattagac agcgaaaaaa gaaatgttca acatgctata
    81721 aacagaactg tatggagagt tcatcaatca atggagtcat ttatacataa tatgaacaca
    81781 attcattcaa ggggtggaaa tcaggtcgtg tttagttcta taaattatgg tacagatact
    81841 tcagcagaag gtagatgtat aataagagaa atactaaaat ctacttatga aggagtcgga
    81901 aatggagaaa caccaatttt cccaattcaa atctggaaag tgaaagaagg tgtgaactat
    81961 aatcctactg atagaaatta tgacttatat gaattagcat gtaaagtatc agctaaaaga
    82021 ttttttccta attttttaaa tttagatgca accttcaata agcatgtaaa atggaaaatg
    82081 tgcgacccaa acagatatat ttatgaagta gcaacaatgg ggtgtcgtac aagggtattt
    82141 gaagatttgc atggagaaaa aacaagtata ggaagaggaa atctatcttt tacgactctt
    82201 aatttagtaa aaatggcatt agaggctaaa gaaaaatatc caaataatga agctaataga
    82261 gttgcagagt ttatttttct tcttgataaa tattcagatg tagtagcaag acaattatat
    82321 gatagatact tatttcaatg tactgctaaa gcaaaacagt ttccactatt aatgagtggg
    82381 ttatggaaaa actcagaaaa tttaaatcca aatgatgatg taagcgaagt tttaaagcat
    82441 ggaacacttg gggtaggatt tataggtcta gcagaatgtt taatagctct tataggtgag
    82501 catcatggtg aaagcgaaaa ggcacaaaaa ttaggtttag aaatcatatc acttctaaag
    82561 tctaaagtag aaaaatataa aaagaaatat aacctcaatt attctgtatt aggcacaccc
    82621 gcagaaggtc tttctggaaa atttactcaa aaagataaaa aaatatttgg agaaataaaa
    82681 aatattacag acaaagatta ttatactaat agttctcatg ttccagtttg gtataactgc
    82741 aatgttgaac ataaagcgaa aatagaagca ccttaccatg aattagaagg tggtggccac
    82801 atattttatg ttgaattaga tggggatgca acacataatc ctaaagctat aatgaaagtt
    82861 gtggatttaa tgaaaaagta caatatggga tatggttctg taaatcatac aagaagtaga
    82921 tgtatgaatt gtggttttga aaacgcagat tcagagttaa aagaatgtcc taaatgtggc
    82981 agcaatagta taaatattat ccaaagaatt acaggttatt tagttggaac tacggatagc
    83041 tggaataatg caaaattagc tgagttaaag gatagagtca cacatggata aagactatat
    83101 ttatatttta gatataaaac atgacacaat tgttgatgga gaagggttta gaacatctat
    83161 ttattgttct ggatgtaatc atatgtgtag aggctgccac aatcctcaat cttgggatat
    83221 aaaaaatgga actttaacta aagtattaga tatttataag gaaatcattt caaataaatt
    83281 ttcagatgta acattttcag gaggagaccc acttctacaa ctgcaaggat ttgttcattt
    83341 agctaaatta attaaaaaga atacaaacaa aacaatatgg tgttatacag gttttaagtt
    83401 tgaggaactc ataacagaca atgaaaagct agaattgtta aaattaatag atgttcttgt
    83461 ggatggaaaa tttgaagaag ataaaaaatc tttagagttg atttttaaag gttcgtcaaa
    83521 tcaaaggata attgatgttc aaaaaacatt gtatgaaaaa caaatagtat tatatgaata
    83581 agagaggctt agccctctct ttggaggtaa atgttatgac caaagaagaa tttattacta
    83641 aatttcttaa agagcagcag agaagaataa aggttttata ttatgaagtt gaaaatttca
    83701 agatggatag aaggtttaat gagaggaaaa agtctaggag acattaaaat gtttctttta
    83761 atataaggag gaagtagcta tatgtatttt gaaacggaca ttataaaaaa taagaatact
    83821 gtaaataaaa taataaaata ttgtggtgga aatactgaaa aattgaaaga ttggctaaaa
    83881 gaaatagaaa ataaaagtat cagtagttta gaagaattaa aagaatatcc attaaaaaga
    83941 aattataaat ttgtattttc caaagaagaa gctcctaatt tagataagct tataaaaatg
    84001 aaactaagag ataattgttt agaaaaatgt gagatttgta gtttagaaaa tctcttaagt
    84061 atgctaaatg atgagatttt agatttaaat aaagaagata tctcttatga agataatatt
    84121 gaatggattg aaaattgtaa agaagaacta attaaattaa aggtaggaag tatttgcata
    84181 gattggtaga aaaataaagg agtgatattg tgagattttg gtgtgagaat tgtaataaat
    84241 acttcaatgc ggaagaaaca ttacaggaat ataattattt tttaaatgaa gagatactta
    84301 tatgccctag ttgcaaaaaa gatttaatac ctatagctag ggaaacagaa ttatcattag
    84361 gttttgatag tgatacaaac caattaactt atgttgaata tgattctagt gattatagtt
    84421 tacttagaaa ggtaaatgca gatgttgaag atgtagtaaa acctataata cattacataa
    84481 gaaatttaaa taaaaatagt ttagatttaa atggaattac agaatagtgc ggaaagccca
    84541 ctcctttagg tgtgggatgg atagcacaaa cagtgtataa aaagtattga cacatacacg
    84601 tataatgtta atactttgta ttctgcccta gatataaaag aaaaatattt aatatagaag
    84661 gtttagaaga tagatttaaa acattagtta aaaataagtg taaggaaatg gatatcgaaa
    84721 ttgttgcaat agaatgcgat aaagaccata cacatatgtt tttaaatagt cttccgactc
    84781 taaatccttc tgatataatg caaaatataa aaggctatac aagtaaaata ttaagagaag
    84841 aatttattga attatcaaaa atgcctagtt tatggactag aagctatttt gtatctacag
    84901 caggaaacgt atgtagtgaa actattaaaa aatatgtgaa aaaccagaaa acaagatact
    84961 agaaagtgag gtgaacacta tgtcaaatta tatattaaca ttgcaattaa aaacagaaaa
    85021 gtttcaagaa gacattatat gtaatgcttt tgataagtat agaaaagtat ataattcatg
    85081 tttatcagag ctatttaaaa gatataacca catgatagaa tctaaagaac accaagcaaa
    85141 ttgtaaatat aagggtaaag atagaaataa aatatttagt gaaattaata agaagtataa
    85201 tttaacagag tattcacttc ataagtttgt taaatttatt ggtaaatatt ataaactaca
    85261 ttctgctata actcagaaga tagctacaag atgttttaat gcttttaata agtatatcta
    85321 tcatcaagct aaacgagtta attatattag atataatgaa ttaacatcaa tagaagggaa
    85381 acaaaattca actggtatta gttataaaga tggtattatt aaatttaata agatgactat
    85441 tccagtaata ataaagaata atgacaatta tgctcaaaga gcgatacaag ataaaataaa
    85501 atattgtaga atacttaaaa aagaaattaa gggtaaaatt aaatggtatg tacaattagt
    85561 cttagaagga attccaccta aaaaaacaac caatcaagga aaaataaaag gacaaattgg
    85621 tttaggtaat gtaggtatag atattggaac tcaaactata gctatatcta gtaaatgtga
    85681 tgttaagtta ttggagttag cccctaatgt taataatata gataggcaaa taaagttaat
    85741 tcaacgtaaa atggatagaa gtaaacgtgc aactaatctt aataaattca atgataatgg
    85801 tactataaaa caaggaaata gagataagtg gatatttagt aatcactatc ttaaattaaa
    85861 aagactaaga aaagagttat atagaaaaca agctgaaata agaaaacaag accactatat
    85921 attaattaac aaattactaa atttaggcaa taagttttat gttgaaacga tgagttataa
    85981 aagacttcaa actagagtca aggatactac tattaatgaa aaaactggta gaattaataa
    86041 aaagaaacgt tttggaaaat cattagcaaa taaagcacca tcaatgtttt tgactatgtt
    86101 agacaataag ttaaaatata ataatgaaag attatataag atagatactg ctaaatgtag
    86161 agccagtcaa tataatcact tttcagatga gtacaataag aaggaattaa aagatagatg
    86221 gaataatggt atggacattc aaagagattg ctattctgca tttttaataa tgaatgttaa
    86281 tgaagattta aaatcaatca acagagaatt gtgtgttaaa acatatgata actttaaaat
    86341 attacatgat aaagagataa atagattaaa aaaattaaaa ttaaatggtt ataaattaat
    86401 atctagtatg gggatataaa aactatatag gttgagaaac gagcctaata ttaatgttaa
    86461 tggtgtcaac agatactttg ttaataaaag tcttagggaa tatgattagt gataatatgt
    86521 tgtaggttat gatttattat aactgagagt attgtagaaa ttcatgtagt acctaagaac
    86581 cccacgcctt taggcgtagg agtttcagaa taacaatgaa tggtaatata taagaataaa
    86641 aagaaggata ttataagaga tgagtcgatg tatgattatg ggatgtcttt gtcatctatt
    86701 atgaaggtta tcttaaatca tcaagaagat atagaaaagt taaaagaaga ggaggtagca
    86761 gaatttataa aaaataaatt agaaaatgag catgattgtg atgaattaaa aataataagt
    86821 gaggtattta atgaaatata ttaaacatgt agataatgga gtaatgagag caataggtat
    86881 tgataattat aaacctttat taaacatcat aaaagaaaaa gtgaatttag aatctaatta
    86941 aaacagtttt aattagcgag gtgatacata tgggattaga tttaggtttt tattcagtaa
    87001 aaacaaaagt tacagattta gatatttatt taaataaaac aagaggtgag aaatataagg
    87061 aattgaataa tgatgaagaa gagttttata agtttgaaga attattagat attgatatat
    87121 ctttagaaga ttggtcagtt attcgtatga tatataaagc caaatgggaa aaaggttatg
    87181 aaagttatga agatgaagcc atacttatta caaaggaaga tttggaagat tatataattc
    87241 cttttcttaa acaaaaagat ataaattcta agatatacaa taaggataaa gagtattatt
    87301 ataaaaatga taaaaaagta acagttgatg ataggtatac acaggagttt tgggatttag
    87361 tattaaaaga atttcaaaaa atgttaaaca taattgattt tgaaaaacat agtttaatta
    87421 ttatgtattg gtattaagat aataatttta atttatttgg aggtttataa taatgaaaaa
    87481 aatgtacata gcaattaatt cagacttaaa tatgagtcca ggcaaagttg gagcacaagt
    87541 tgcacatgca gtttatgatt atttgtataa caaaatttta gacactgttt cttgctctta
    87601 tgaaacagaa ataatagcac atgaattaat agatttaaaa tgtgatttaa cgtcatttaa
    87661 gaataatggg gatacaatat gtatattaaa agctaaagag gcacaattat taaaatttaa
    87721 agaaaaaggt tatttaacta tagtggatag aggattaaca gaaattccta aaaatagcat
    87781 aacatgtgtt aacttaggaa tatttaatga ggatgaaata ccatctacaa ttaaaagatt
    87841 gagattatat taaggagaaa gacaataaat gtattctaaa ggtgatgtag taaaagtatg
    87901 gtgttatcaa tgtgaaagga tagaatttca agaatttgta ggatatttta attcttattt
    87961 tgataattat aaattaaaga aacgatggaa atgctctaag tgtgatgtca tcaataattt
    88021 ttaagagttt aattaatgga ggaatgagtt atgaaaataa agaaaataat tttaggatta
    88081 gataacttag agaatgtaga gttgggtatt ggagatgtag gaggttttta tttagataat
    88141 atacatgaaa ttattggagg atttgctttg agttatatag gtaaatgcaa gaaggcagat
    88201 tatttacata tacaaataca taaacgtgtt gatgaaattc aaagattgca tgattataag
    88261 gatattacaa atgtaaagat agaatacgaa gacggaagtg tggaggatat atatgtacct
    88321 tataaacaag aaggggattt cttgggttta gataatcttt atcaaacttc ttttattagt
    88381 aaacaaggtt atttacatat agttatctct aaggataaaa cagtagaaga agtcttcaat
    88441 gaagaatttg aggatgatga aggggtagaa tttagtttta atatgtatgg aatataaaac
    88501 ttaaaatgga aggagatgag caaatataat taactctttt aagaaattaa taaagtcaaa
    88561 atatataaaa aataacgaat caataaaacc attagaaaga atttttgaat atgaaataag
    88621 aatcaaagaa aaaagaacat attttaattt agaattattg atttatgaaa aaagaattaa
    88681 gataattaaa aaaatatttt taaaagatat actatgccat tatcgaagag atatagaaca
    88741 actcgtcatt tatgacctgg ataaatatct taatatgaca gataaagaaa tggaggaata
    88801 tattataaat ttaataaaag ataaaataaa agaagagtat ggggagaata tacttcctga
    88861 aatactaatg gaaaaattta taaaactcga aagaaaaggt tcggtgactg tagacgtacg
    88921 ggatttaata gagggataat aaataacaag ttaaaataca ggttttaaaa ggagaataac
    88981 aaatggaagt tcaagggaaa tataacaaag ctaaaatatt tacagagaat gtagattcga
    89041 taacaatagg acaaataata aatttatgta atcaaaagga atttaaagaa tccagtataa
    89101 gaattatgcc tgattgtcat gctggtaaag gatgtacaat aggaacaaca atgactataa
    89161 gtgataaagt agtaccaaat ctggtagggg tggatatagg ttgtggaatg gctactattc
    89221 cattagaaaa atatattaat aatataaatt atacaaaatt agataagatt ataagagatt
    89281 atattcctca tggatttaaa atacataata agtcaagaga aaaactatta aagaatttat
    89341 ttaatataga cataaataat cttagatgcg aggtgaataa aaatagagca tatatgtcgt
    89401 taggaacttt aggtggaggc aatcacttta tagaagttga taaaagtgaa aaaggtcaaa
    89461 tgtatcttac tgttcataca ggttcaagaa atttaggaaa acaaatagct gattattacc
    89521 aagacaaagc tataaaatat tgtattgaaa aatataaaaa gtcatatgat gatgcaaaag
    89581 agtttttaat atctactcta aaaaaagaca ataaagaaca tttgataaat aaatatttga
    89641 aagaccttag tgatagaaaa ttgaataagc cacatgatga tttatgttat ttagaaaatg
    89701 atttaatgga agattattta catgatatga gtatagctca aaaatacgct gctgcaaata
    89761 gaatggttat aattgcggat atattgttta aatataacag cctagaagta aattatgacc
    89821 attttataag agatattaaa tgtgatgtta tagaatgtat tcataactat atagatatgg
    89881 atagtaaaat acttagaaaa ggagcaattt ctgcaaataa agatgaaaca gtaataattc
    89941 cagtaaacat gagagatggg attatattag gaaaaggtaa aggtaattct gagtggaatt
    90001 attcagcacc acatggagca ggaagaattt tatcaagagg aaaagctaaa gaaaaaatat
    90061 ctttagatga atttgaagag tctatgaaag aaatatttac aacttgtgta ggtcaatcaa
    90121 cactagatga agcaccacaa gcatacaaac ctatagagga tatcttaaac aatataggag
    90181 atactattga gataatggag gtgttaaagc caatttataa ttttaaaagc aattagaatc
    90241 ttgttattta aataaaatca aaaggagaaa aaagggtatg ataaaattaa taacacataa
    90301 tgatttagat ggtgtaagtt gctgtattat agcaaagtat attttacgag aacaaataga
    90361 tgttaactat tgtaattata aaaatataaa tgatgtagta ttagatacat taaaaaatca
    90421 cgataaatat gaacaaatat taataacaga tatatcagta aatgaagatg ttgccaagaa
    90481 gttagatagg attaaaaata aagttcaatt gcttgaccat catccaacag cactattttt
    90541 aaataattat gattgggcta atgtagaaat agagtgtaat aaaggcaaaa catgtgggac
    90601 tcaaatgtta tttaattatt tacaaagata ctatgatgat acttcagaat ctacattaaa
    90661 atattttata gaacttgtta gaaggtatga tacatgggaa tggaaagata aatataatga
    90721 tttagatgcc aaatatttaa atgatttaat gtatattatg ggaatagagg attttataat
    90781 ggacatgtta actaaaatag atagtgatga gatgtgtcta tttgataaat taagtttaaa
    90841 attattagaa ataaaacaaa aagaaataga tagatatgta gagaaaaaag atgaaaatat
    90901 aatggttaaa gaaattctag gatataatgc aggaattgta tttgcagaaa atcatataag
    90961 cgaattagga aataaattaa gtgagttaca tccagaactt gattttatag ttataattaa
    91021 tcgagaaatc atttcatata gaactataaa agataatata aatttaagtg aaatcgctaa
    91081 agtatttgga ggtggaggaa atccgaaagc atcaggaagt cagattgatg agagttgtat
    91141 agataattac ataaaagata tatttaatat aaaatcttaa ttttaaatgg aggtatatat
    91201 gaaatttgaa aacaacatga ttaaatacaa tttagattta ataactatga tatgtaagat
    91261 gaaactaata atttatgagg tgtaataatg atgatagata aattcaatta tgaattatat
    91321 aatgagtttc cacatttatc accaataata gaattgtata atttaaatat agagtacata
    91381 agagaagttg taagtatact tatcaataca gatatgacat ttcaaaggtt taaatattcc
    91441 aaatctagag ttgagtgttc tatgaaagcg tatattattt cacctaatag taagctaagt
    91501 gttgtatttg catacgattg tgaattaaat ggaattgact tagacaacct gaaggcaatt
    91561 atatgagtat aaacaaataa aaataatact ttacaagaaa ggtaaattga atatgtgtaa
    91621 gttttgtgaa agtataattg ataatacaaa agatatactt ttaacctcaa gaagtagatt
    91681 attagaagac aatacatgtg aaattatagc agaagataat tgtaataatt gttatgatgg
    91741 atgttatgaa tatttcaaac taaacggata taaaatcagg ggaaatacat atgttaatgt
    91801 cgactactac aaaaaaatta gaaaaataat aattgctcca tgttcagaat cagtacatat
    91861 aaactattgt ccatattgtg gtaaacaagt ttctaaagat ataaaagatt ttaattgtat
    91921 tcctgagcat atagtagatg ttagatataa aaatggtgat gtatatgatt atgatatgga
    91981 aaagtctgta caagaagtca tggataatgc aaataataat taaataaaat gatactttta
    92041 ataggggata aatatgaatc tttggtctaa aattgaagaa ccagtgatga gagcagtaag
    92101 tggaatagta tttaatatat ggggaaatgt ttgtttttcc atatattaca tagaagaaaa
    92161 taaacaaata gagttagaaa tatatgatag accttataga tatgaaggta aaaaaaatag
    92221 ttgttgagaa gttatttgat tacaagttaa taaatgcaga ttataaagaa atacatgata
    92281 ttgtttctat gatagaaaga tttttactag aaaattatta aaaggagata tttaaaatga
    92341 ataaaggaat taaaaactat ataacagcag tgaattactt acttgataat ttagagtata
    92401 tgatggagga tgacgaattt aataatgaaa agttacagaa aagaattgat gtaattagaa
    92461 aatttgaaag agaattataa gatgggaaaa ataaaaaatg gagaaataga tactgaagat
    92521 tataggcttt ttaaaaacat tcaaaaagaa aaagatagag tatatagtaa gtacattaat
    92581 gaagaataca taatggaaga attcataaac tacttaagat tggaagataa agattatact
    92641 acagaaatat tagaaagata tgcacgatat attgatgaaa atttagacaa tcgttgtcca
    92701 tattgtgtat ataatatttg tagtgaacat gataattgtt ttgatggaat acttgaaaat
    92761 ttaaaagaaa aaattaaaat aaaataaata ttttaatatg aaaggatgtt gtgataataa
    92821 gtataagaga aattatggaa atagatatag aaaatctatc aatgaagcag catgaagtga
    92881 ttaaaatata gaattattaa aaaaatatga tacatatata tataagaagg ggcattatag
    92941 agaaatgata aaagagagat ttaaagcaaa agatagcttt aatatggatg agttcactaa
    93001 aatttggctt atggatttta aagaagattt tgatttaagc ttaaagaaaa tgatagaaaa
    93061 tacgataaaa aaatcaataa aagatactta tgaagaaaca gaaagggcga taacaaatat
    93121 agaaaatctt ataaataaac tataagtcaa aatattacta acgacacctc taatataaga
    93181 ttagttatag aggaaatcta ttattagaga aggcatagat tgcgtcactg gaacaattca
    93241 agttaaaaac ttagataatc atatcaaata aaatctttta caacaaatca aaatttctaa
    93301 aataaattct tattaataat tcaattaaaa ctaaaggagt gaaattatat tgaaaaagtt
    93361 tttattaaca gggttattag gaacaatgtt aatagccatg tctggatgta caggaataca
    93421 aagttcaatg aaagatgctg aaagtgatgt atcagggctt aatagaactg taaatgtata
    93481 ttcagataat ggcgaggtat taaaaacata tacaagtaaa agcatgagag ttaaagatgg
    93541 agatggtggt actataacac tagattttga tggtaaaagg gtgattatat gtaatgctca
    93601 tgtagtaata gaagaaaatt catctaataa ataaaggaga gttaaatgtt taaaatttta
    93661 aaaacaattc ttataataat ttgggtagta gatattttaa acttcccaca atttcaattc
    93721 ttagatacaa catatccaat caatacctta gcatggttgc taatctggat tcttatacca
    93781 tcgagtagta tatatattga caaaaaagaa taaaagaaag gagtattaat ttgattttaa
    93841 atattgctac aatttttaat ttaggttgta tggtggctaa ttacttgcaa gataatacta
    93901 atgggatact acttaatgga ttttgtctta tagcattatt attattgaat aatgacttag
    93961 attaaaagta ttattttaag gagattaaaa gatgaaaata acaatatcaa ttgaagaagc
    94021 aatggatatt attaaacaac actatgagaa taaaggaatt gaaatcaaag acttaagttt
    94081 taatttagaa aaaactggaa tggttagaaa tattaaattt aagggagaaa taatacttaa
    94141 gtaggagata tttatatttg ttaaaaaaaa ggggaagata tttataagta gtacaaatag
    94201 aagtgatgct agaagtttcc atataagtga ttattataga actccaatta ctaaaatcaa
    94261 agagttttta actgagttca gtagatatga aaatatactc aattcaaata taaaaatatt
    94321 agacccatgt gcaggtggag ataatacaaa tccaatgagc tatccaactg caatccaaga
    94381 attttcaaat caagaaattt caatagatac agtagatata agagatgatt caagagcaaa
    94441 tataaagcaa gattatttaa agtttcagcc aaaagaaaaa tacgatgtaa ttattactaa
    94501 tcctcccttt aatttaagct tggatataat taataaagct ttaaatgatg taagagaagg
    94561 tggtttcgtt attatgctgc taagattaaa ttatcttgga ggaaaagtaa gacaaaggct
    94621 gtggggaaat aatatgccta aatacatatt tgttcacaat agaagaatga gttttacaga
    94681 tgatggaaag acagatagca tagaatatgc tcattttgta tggcagaagg ggtataatcc
    94741 aaaattttct cagttaaaag tattaataag tcaatgaaat agaggtgtaa agtttattag
    94801 agatggaaat aaatagaaga agatgtgagt atgctgccag aacaggaaga tatcctaatt
    94861 ctcttatttt gtgggaaggt tactatagcc ttcttaatat ccaatatata gaggataaaa
    94921 caagaggata tattactaaa tttaatggca tggatgttat aaaatgtaat gactttttaa
    94981 aaatagaatt atttgaaaag aatattaata attaaaattt gttttttaag ttgaggtgat
    95041 gagttgagat ataataatta tcatagtcat aaaatttatt caaatataag gtcgttagat
    95101 gtaattacta aaccacaaca atatatagat agagcaataa aactaggtca aaatacatat
    95161 tttacgacag aacatggata tcaaggaaat gtatatgagg caaaaacttt atgtgatgaa
    95221 tataaattaa aaatgattat tggagcagaa ttttactatg taaatgatat aaatgagaaa
    95281 gatagaggaa attatcattt aatagtaatc gctaaaaata atgatggtta caagcaaata
    95341 aataaagctt taagtttagc taataaaaat ggatattact ataaaccaag aatagatgaa
    95401 aaaatattat ttgagatatt taaaccaggg gatgtagtta ttactactgc atgtgtagct
    95461 ggaatattaa aacttgagaa tagagaagaa ttaatactaa aactaaagaa ttattttaaa
    95521 aataatttct ttcttgaagt acaatctcat cctcataaaa ctcaagcttt gcacaataag
    95581 gatgttttag aattaagcaa caaatataat atagatataa tacacgccaa tgacagtcat
    95641 tatatttatc cagaagaatc aaaatataga actaaatttc ttaaagctaa aggtataaat
    95701 tatcctgaag aagacggttt tattttagat tatccaaatt cagaggatat atttaaaaga
    95761 tatgaaaaac aaaatgtatt aacaaagcaa gaagttgaaa gagcattaaa aaatactcta
    95821 atatttgatg agtgtgaaga aatcacctta ataaatgatg atataaaatt accatcaata
    95881 tctaaaaatc caaataaaga actgaaagaa atattaaata aagaatggtt agagaaaaga
    95941 aaaaatatac ctaaaaatag atggaatgaa tacttagatg ctataaggta tgaatttgat
    96001 attatagaga aaactcatat ggaggattac tttattatag attataaaat agttcaaaga
    96061 gcaaaacaag aatataatgg tcttcttact aaaacaggga gaggttcagc accttcattt
    96121 ataataacta atcttttagg gcttactgaa atagatagat taaatgctcc agtaccatta
    96181 ttccctacta gatttatgag tgttgaaaga atactatcag caaaatcttt gccagatata
    96241 gatttaaatg ctgaagatgc tgaaccattt atacaatcaa ctagagattt attaggagaa
    96301 gaaaattgtg catggatgat aagttataag ccattacaag atgcttcagc ttttaggcta
    96361 tggtgtaaag caaatgatat gaaactatct gagtatgatg aagtagctaa aaacttagat
    96421 aaatatacaa atgatgtttt ttggaaagat gtaataaagg aatcaaaggt atttgtagga
    96481 gtagtagaaa gtgtttcttt ctcaccatgc tctatgctta tatatgatag accaattgat
    96541 gaagaagtag gattattaaa aactaaggat ggggtatgtt gtaatataga tggatattat
    96601 tgtgataagt ataaatattt aaaaaatgat tatttaacag tgaaagtatg gtcattaata
    96661 agaaaaattt gtgaattagc aaatattagt attcctacaa ttgaagaact aaacatctta
    96721 ttagatgcta aaacctatga catatataag gacaaattaa cttgcactat aaatcaggta
    96781 gattcagact atgctacaaa cctggcatct aaatacaaaa tatctagtgt ggcggaaaca
    96841 agtgcatttg tagctagtat cagaccagga tttgcatctt tattagacaa ttttattaac
    96901 agagagtcat atacaactaa cgttaaagaa ctagatatat tattagaaga tagttatcat
    96961 tatcttatgt atcaagaatc aataatgaaa tatttaatat ggttaggaat agaggaatct
    97021 gagagttatg atattataaa taagattaaa aaaaagagat ttaaggaaaa agagttgaaa
    97081 gaattgcata tcaaactaaa aaataactgg attaaaaaag tcggaactga aaataatttt
    97141 gaagatacat ggcaagttgt aaacgatgct gcctcatatt cctttaatgc ttcacatagt
    97201 ctttcatatg catatgacag cttatactgt gcatacctta agtcacatta tccattggaa
    97261 tattatactg tagcattcaa tttatataat gaagatacag agagaacaag aaaattaaca
    97321 gatgaaatag agtattttag tattaaatta gaaaatccta aatttagatt ttcaaaatct
    97381 gaatacttct ttaatagaga cacaaatagt atttacaagg gcattgaatc tattaaattt
    97441 ttaaattctg atataggaga gtatctatat tctcttaaag ataataaata tgattcattt
    97501 ttagagctat taatagattt gcaggggcat ataaactcta aacaattatc tatactgatt
    97561 aagctagatt tctttgagga atttggaaag tccaacaaac ttttagagac ttatgatatc
    97621 tataactcaa tctatagtaa aaaacaattt aaaagagata atttaccatg cgatataaat
    97681 accatgagaa aatactctaa taaagaaaca gaaaaaatat ttaaagaagt tgatacaaaa
    97741 gaattatgtt cttatcttga aagtcaaatt gaaaatacag atataccaac caatgaaaaa
    97801 atacaagctc attttgagtt tgtgggttca tgtaacataa aagatagcaa ttcaaatcca
    97861 aggtattgtt tagtaataga tatagatact aaatattctc ctaaagtcac attgtataat
    97921 ataagttcag gaaatataaa gattttcaaa gtaagtaaac ctatttttga ggataataaa
    97981 attgatgttt atgatttagt ttatttaaaa tcaattaaag aaaaagctaa aagtaaaaaa
    98041 gtagatggaa aatggattag gagcaataca gaaacagaat ggtggataca agaatattgg
    98101 aaaatagaaa attaagaata tgacctcgta tatgcgtttc taagagttta cataagagtc
    98161 tgcttgtatt tatacattga tttcttaaaa tggcatatac gaagttggtg aaaggtagtg
    98221 atttcaatac ttatagatga acaaagatat tatagcttat tggaagaaaa aaaagaccta
    98281 agtatgagaa tcgatgaatt aaaagaggaa aatgcttttt taaaacaaga aaatgaagag
    98341 tatgaagaaa ttcttaatga gtgggaatgt gtaagaaaag aaattgtagc aacttgtaaa
    98401 aaaaaagaaa tattaggtga aaaaccaagt gaattagaaa tggttcttca aaaaatagag
    98461 gatatataat gagtgtaaat aaaatttatg agaaaaaaga atacattatt atcaaatcaa
    98521 aatctggata tatagtttat aatacaaata aagagtttaa agaaggccac actcacttaa
    98581 aaagttataa tgctgctaaa acagctatag atttagttat taagagaagg cttcctaaaa
    98641 gttattctat ttattttctt acaagtttga tgagaatatc taatgatgta caatatataa
    98701 aacatataag cgatattgta tatataagaa ataataaagg actaaaagaa aaatatataa
    98761 attctaaaaa tattaaaaaa aactattgag aacatagaag gtatatgata tactatgaat
    98821 ataacaagaa catagaaggt aaaaaggagg tagtgattaa tatttgaaat cttataaaga
    98881 aaaacagttt ttagtatttg aatttgaaga tgggaagaat gtaaagtata atttggcaac
    98941 aggagaatac gttggtaaat ctggaaggat tgtaaaagat gtgtgtactc aacttagagg
    99001 atataattta catgaggtaa taaattcttt tgaagatgaa aattataagt gttttttaaa
    99061 ttttgtagat ggaagagtaa atagaagtaa gagtagcaga gcttggggaa ggagggttga
    99121 aagaataaga aatataggaa gttttttaaa tgaaataaat aattattctg agtatgaaca
    99181 attattctca gcaggattaa aaaaaataat ttatccgata cattgtgata ttaagagtat
    99241 acctaaaggt cttatttcta tctgtaggaa ttatagtatt actttgagtg accgattgat
    99301 acaagggtat agtaaaaacc caaatttgta taataattta ttaagtttag aattgaattc
    99361 aataagaaaa actaatttaa tttcaattct tgattctggt tatgatagaa tgatatttga
    99421 taggttaata gacatatata aatataaacc tcaatcactt ataaattata tagataatct
    99481 gatgacatat gaagcattaa atgggcttga aagcactcta aacgaattat atgactatgt
    99541 tgttatgatg agtgtaataa gtgataaata tgaaaaatat ccaagacatt tcttaacaac
    99601 tcataaaata gcatctcgaa attataatcg tcttaaaact caatttgaag aagaagtatt
    99661 taataaaaga atagacaagt cactagaata ttcatatcaa gattataaat ttatataccc
    99721 taaaaataca aatgaaatta aagatgaagc agtacaacaa aataattgtg taagtagtta
    99781 tattcaaaat gttatagatg gaaaatgtca tatattattt atgagaaaaa aggataatcc
    99841 aagtaaaagt ttagtaacaa ttgaagttag aaatggcaaa atagtccaag ctaaaggtaa
    99901 atataataga gatgtcaatg aaagagagca agaagcaatt gataaatata ataatagaat
    99961 agaaaggatg aagaaaatat gttaatagaa ggaactaaaa taagattaat gaaagaaata
   100021 caaggttttg agatgttaaa aataggagat atatttgtta ttacatctgt gggaaacaat
   100081 ggagctatac atttcaaaac aaattatggg atgggattca tgaattatag tgaattaaaa
   100141 aaatattttg aagttgcaat agagactaag aaaaaagaac atatttggag cgaatggaga
   100201 actgcgactg tatttggaac aaataaaact tgcacatata gaacaaatgg aaagaaagta
   100261 gaagttagaa tgggagattt taaagcatca gctacttgcc atgattcaga tgagtttgaa
   100321 ttaaataaag gtgttgagtt atgtctggca agaattgaag ttaaaaaagc aaataaacag
   100381 gtgaatttag tattagataa aataaataat aaagaaattt aggaggttag aatgagttgt
   100441 aaatttaaag aaagatgtga gaataaaaat agagattgcg attattgttg ttataatcca
   100501 aatgcatatt tagaagatgc ttttgaatgg aatggagaag ggagaaagcc aacagacgaa
   100561 gagttagatg atgctcttga agaataaata agtatttaaa attatcattt taatatgatt
   100621 ggaggtcttt atgaggtgga gaaatatatt agtaacaagt gttttagtaa tgggtagtag
   100681 catacatata tttgctaata ctaaagaaat gagtactagc aggatggata aaaatattgt
   100741 agcagataca gctaaaaata ttaacttaat gtataaatat gagtgggagc aacacaaaaa
   100801 tagttctgaa tataaattag aaatcaagag aattaattta gaaaaggact taggaataaa
   100861 aatagaaaaa ttgattcctg taacatggga agtaagttac tatacttctt taaactgtga
   100921 aaatagtaaa tatggagcta ttacagctac aggagaaaaa ttacaatatg ggtttgtggc
   100981 caataattat cttaaattcg gaactaaaat attagtcgat ggaaatttaa aggtggttaa
   101041 agatagaggt tctaataaat attttggtaa ttctaatgct atagatgtat ttgtaccaaa
   101101 attagagggg gagagtgatt ataaatatta taagagagta aacaacatgg gaagacatta
   101161 taaagaagga tatattatag ttgaaggtta ggagttgata aattgaatgt aaatggaata
   101221 aaaataccag gaattattga tgtgtcaaat gtgtatgttt atggaattaa agaaagcata
   101281 attgcaagtg gttatccgat gtatgaacaa caggtaatag atatgaaaaa aataaacatt
   101341 tcagaaaaag atttaaaacg agcaaatcaa ttaggcaaat caaaacaagg ttcaggtcat
   101401 gattgctttt ctaaaggaat tatcattcaa atggatttac aatggtcaga atatatgtgg
   101461 agacaatggg acagatatca tcataatgat tatgtgtcta gtcaaagtaa aatgcataga
   101521 ttatctaaat ttaatcttga tgatatgtgt aataaatatg ttgataaaaa tacaataaat
   101581 tttctaaatg aattaattca tgagtacaat aactttgaag aattgaaatt gaataattct
   101641 aataatatta ttcttagaaa tggagaaaaa gttgaagtca caaaagaaac tctttggaaa
   101701 atcataatat caaattgccc atcaggattg atgctaactg caagagttac attaaattat
   101761 ctacaaataa aatctatgat aaatcaaaga gaaaatcata aaatggagga atggagaatt
   101821 ctgtgtgact tttttaaaac actaccaaaa tataaagaat taatgatgta atagttttgt
   101881 tagcaattaa attttaaata taaaggagaa gtgggtatgg cagaaaaaag aataaattat
   101941 aatcaagtat ttgtatcagg agaagtttta gacattttaa atatagctag aatgaatcaa
   102001 ggaactggcc aagaagctat aagatttacc ttaaaggttg aaacagcacc aaacgaatca
   102061 gtaaatgtag attactttac atcaatgttt aagtcagatg gttcaccaaa tcaaatgttt
   102121 ttaggaatag agacaatagc taatgaaata aaaactagag cagaagatgg aaaaggtgat
   102181 attgttagat gtgtttgttc attagacaat aacttatatt ataaagatgg tgaaaagaaa
   102241 gagcgattcc aaatatcagg aactttttgc aatagagaaa aatatgatga caaaggtaat
   102301 cctattgatg acaaaggcga agtagtaaag tcaataaaag cgagtcaggt ctggagagta
   102361 tatacattaa ttgaaaatat agaagaaaaa gaagatgatt taggtaagta tttagagatt
   102421 aagggtttaa ttaataaata tggtaagcaa ggttgtaata tgacatttag aatacataat
   102481 gaagatatga tagaaggatt taaaagttta tataaaatag gagatgttgg ccttcttgaa
   102541 ggtacagtaa aatctatggt tgttagtaaa tcagcaggat ttggttcaag aattaaaaaa
   102601 agtgctttta catttttaga aatagaaggt ggcgatgaac ctttgaaaga tggagacaaa
   102661 atatttagtg ataaaaatta tcctttcaca gataagaata tagaggcaat gagagaaaaa
   102721 ataaaagaaa aagataaaaa agaaaaacaa agagatattg ataaaaatgg taagacaatt
   102781 gagataagag atgatgatgt accattttaa attataaatt aaataatcta ttaaaaagga
   102841 gagatgtgaa tggaagttaa agaaaaaaca atgaatgatg gtttcaagaa agtggtaaat
   102901 gaggaaataa agacgtatat atcaaattta tattcagata gaatagacgg attaaaagag
   102961 agtgatagtc aaattgagat aacaaaagca ttaatagcct ttcatttaga tatagaatca
   103021 attccaaagg ataatacaaa cccatttttc aggtctaaat atgcaaacct tgatacaatt
   103081 cttaaagcag taaatccatt attagcaaaa catgatttaa tactaatgca atcagcagaa
   103141 gatgcaggta atgataaagt atatataaaa actaaactaa agcattcatc aggcgaatac
   103201 atagagtcaa attctgcacc atttaaacca gctaaaacta atgatataca agctagagga
   103261 gcattggaaa cttatttgag aagatatgca gttcaatcag tattagcatt atcattcgag
   103321 gaagacgatg atggaaattc tttaacaaac aaatcaaagg gtaaatcaga agaagaaaat
   103381 tcaactatta agaaaagtag agtgtaaata aaattgctac ctcttaaatg aggtagcaat
   103441 aaatacataa cataaggagg ggaaatcttg aattgtaagt gtaggttttg taaaaagaaa
   103501 ttaaatacaa atgatgctta taaagtagag catattacat ctgggggaaa taagcagaat
   103561 agatattatt gcaatgaaca ggaatataga aaagagcaac aggatatata tttctggaaa
   103621 caatgtcaac ttggaataga ttatattatg ggatatacag ttataaataa tcaaaaaaat
   103681 aagatgttac aagagataat aaaaggtggt tatacgagag aagaattata tgattgcatc
   103741 attgagaaga aagatgaagt tatagaatta cttaactata gaaaagatat agaagaagaa
   103801 tatcctaaat tatgttatgt gtttacaata ttgaaaggaa gtattagaga tataacaatt
   103861 aaaaacaagc aaatgaaata tgaaaaagaa aatgaaagga tatacaaaga agtagagaaa
   103921 agtgaagaat attatgaaat aattgctcct aaaaaagtaa tttataataa aagacaaagt
   103981 ttatttgaca aagtgaaagg agtgtatcaa gacgagtagt tatgaaaaaa taatagagga
   104041 taggggtatt atagaaacat tggttttagg cacaatgtta aaatcattaa ctctttttag
   104101 tgaatataaa attagcgaaa gtgactttat aatagataag gtaaaattct ttttctcgtt
   104161 aggaagaata atgtctaaaa cacataacga gcttgatgaa ataagtgtag ctaaatttgt
   104221 atcttcaaat aaactcaaat ctgaatatga aagatatggt ggttggaata gtttatcatc
   104281 tgctatggag tatggaaaag aaactaatat agcagcatat attgatgatt tagctaagaa
   104341 taatttacta attgctttag ataaaagagg ttttaatgta ataaaagaaa tggagcataa
   104401 tgggttaaaa tttattccat ttgaaatatt tcaatctatg aaatgtagag aagtggaaga
   104461 attttatgag gggttaatat cttcatgtag tgtaaattct ataaaaaata atatgaaagt
   104521 tgaaaatctt ttacttacta aagatgatag agaaaaatta aagcaaaaaa ctgaagcagg
   104581 aacaccttat aatattatat ttgaatacac tgaaaaagaa ataggattga gtaataatga
   104641 agaatctaag tatatatata gcttaccaat attatcaaat aggactaatg ggattggtaa
   104701 gggtggtggt ataaatataa tagcagggtt ttcaggcata ggaaaaacta ctttactatt
   104761 ttttaattac atattagcta tgatatatag aggagagaag atagtcatat ttgcgaatga
   104821 acaaaaatct caatatttta agagtatgtt agtatcgttt atagcatata acatatttaa
   104881 ttatcatgat ttagatagaa ataaaataga taatggagat tttacagact ttgaagaaga
   104941 cttaatggaa aaaatagaaa aatttttaag agatagatgt tttgcagaga atctaaaatt
   105001 tatctatatg gaagaatttg aaatatctga aatactaagg aaaagtaaag aacttgttac
   105061 acatcaggga tttactggaa tagcagtgga tacatttaaa tcagaagatt cgtcagatgc
   105121 acattataca ggaaaattaa ttgaaaattc taaattactc gatagttttg ggaacaaata
   105181 taatgtaata actatgttat ctatgcaatt acttacagct caagaaaata aaagctcata
   105241 tctttcggca ggagatttgt cagaagcgaa agctgtcaaa aatgtatgtg gtttattaaa
   105301 acttatgaga aaagtagtaa atgagttaga attagattct actaacaaga aattcttttt
   105361 aaaaccatat aaattaaaat ataataaatt aaaaaagact actgaaagag aatatatcca
   105421 gtttgatgca aaagatttgc aaaaagaata tagattatta tttttaaata agtcaagaag
   105481 aggtcaagat ggagatgtaa ttttactaag attttatggt aagactggta gattagaaga
   105541 gataggaagg tgtgagaagg tctacagagg acaattgtca tactaggtga tgactatgga
   105601 aataaaggat ttgactaatg aacaggtgat aaattttatg gaatatttag gttcggactt
   105661 atctcctaaa agcaatgata gacagttaat attcaatact tgtttatgtc ataatggtga
   105721 ttcatacaaa ttattttatt atacagaaag caaaacgttt cattgctata gttcttgtgg
   105781 ccatataggt agcttaatag atttattaat acacataaat aaatatgagt ttaaagatgc
   105841 tattaatgaa ataaaagatt tctttggtat ttcaaatcaa ccaatgctaa gaaaaggatt
   105901 tagaataaag aaaaaagtag aacagataca tgatattaaa gatatacaaa tagaattact
   105961 tcctacccct aaaaagccat atgtatataa aacttttcag caagtcccaa ttgaagagtg
   106021 ggaaaatgaa aacatatctt ttgaagtcct taaaacatat caagtatatt ataatctata
   106081 tgaaaatcaa atagtaattc cacatttctg ttggcatgat agagctaggc ctgttggtat
   106141 tagagttaga aacttagatg aagataaggc taaaagtttt ggcaaatata ttccattatg
   106201 gtacgacaat aggtgctata atcatagatt aagtcttaat ctatatggat taaatgtaaa
   106261 taaaaaatct atcaaaaatt ccaaaaaagt tattgtattt gaaggtgaaa aatcggtgtt
   106321 acaaatggct actatgtata aaaataatcc ctctgtagct atatgtggga gtaattttag
   106381 tagagagcaa aaaaagatat taatagattt aggtattgaa gaattaatca tagcttttga
   106441 tagacaattt aaagttaaag atgatgaaga atatgttata tggagagata agatatataa
   106501 attagttcaa gatattaaag atgtagtgaa tataagtgta atatgggata aatataattt
   106561 attgggctac aaagatagtc ctagcgataa aggaaagaca atatttgaaa aactattaaa
   106621 aaacagaatt aatatagaga actttgttaa acaataaaaa agtaaagaaa ttaattttat
   106681 gagaaaattt ttattgttta gggatttatt agcagatgct aaataaaata tgtgttttaa
   106741 tatgaattgg aggtagatta catgataaaa tttttaataa aaaacgtaca catgggagat
   106801 aaattatatt gtataaataa cataggaaat tataaaaaag gtgaaattta tacagtgagt
   106861 gatactagtt tttttggact ctttcataaa actaaaggag aaaattgctt accaattgaa
   106921 tgttatttta tacacttacc aaaaaaagaa gagttagaaa gtaatcctaa atcaatgact
   106981 aaagaagaaa ttgaagatga actaggatat aaaattaaaa tagtttctaa ataataaagt
   107041 gaggtgatat tatattgagt atcttcaata aaaaatatgg tagaaatgta aaaataacag
   107101 aagaagaacc tccttctcct cctcccaaac aaccaatata taatagagat aatatacaat
   107161 atgataaaga aatggaaaga aaactattag atattgatag gttaaaaata gaattggaaa
   107221 aagaaaaaaa gatagaagaa gaaagaaaaa aagtagaaag agtaaaggaa aatgagggaa
   107281 aggaatgggc ttgggttgaa ggatataaat gtacagataa aaatatgaaa tgtaaggaat
   107341 ttcaatatga attaaacaaa gcctatagta tggatggtga tgatattaat atatggaatt
   107401 ggggattcca tttatgttta gacttgggtg acgtatttca atattatgct ccaaatttaa
   107461 gcaatagatt ttttaaagta aaagctctag tgaaaaaagc cgataaatat aaatatggta
   107521 aagaatatgg tgaagtgact ctcctttcag gtagtgtttt acgtggtcat aaaataaata
   107581 aaatagctgc taaagagata atatttttag aagaattaac ttttgataaa ttaaaactac
   107641 atatacaaaa tagttttcct gaagtaaaca ctaagtctaa atggtatgcc atatgtaaat
   107701 taggagaaca agaatattat catagaatgt ttatgaatca aatgaaaaag attagatttt
   107761 cagatacatt ttctcaatta ttatttgatg aatgtcgtaa ttattgtgaa atattagaaa
   107821 tcttaaataa agcaatagca tattcaaaag aaaatttatc taaagatatg ataatatatt
   107881 tgcttatgaa agatataaga aagtaacata taaaaagaag ggagataatg tggacaaaat
   107941 aaataagata gatttgatta agttaaaaga aatgaatata tatgataatt atcaattaaa
   108001 aaaaatagca agtaaaatga tattacatct aagatatgaa ataatggact tttgtggttg
   108061 tggttctcct gaagatatat cttttatgat aaaaggagta ttgactgcca tacaaaataa
   108121 agaaaaaaat tgtaatttag aatacacaga aagatgttac atatttgaaa tagaatttaa
   108181 taatgtttgt ggaataattg gtagtaaaaa tgatttgata caagaattta tattaaatgc
   108241 tttaaattca tatgggttat tagaacatgg tagtagcatt tgggggtcat ggctatctga
   108301 ttatggtaaa caaatattat gtgcttttga aatagttggt gactgtattt tagatgttag
   108361 ctatttagat taaaaagtta gttttaatag gaggtggtaa ttattaaata tgtaatgagt
   108421 gacttacatg gtatgtatga taaatttatt tcaatgttag agcaaatcaa tttcaattca
   108481 aatgaccatt tgtatatttt aggagatgta ttagatagag gggataagtc tttagagatt
   108541 atagattata taagaaagta taagaatata actcttctaa aaggtaatca tgagttaatg
   108601 tttcaagaaa gttatacaga tgtaaatagt agttttcttt ggttttataa tggaggtaaa
   108661 gatacatttt atgatttagg aatgaagtct tatgaatata aagaaaattt ttataaatat
   108721 attaagaacc ttccatattt agagataata gataatttta tactagtcca tgctggacta
   108781 taccttccaa ataactatga gaatctcagt atagagcaaa taattgagtt acaagaagaa
   108841 gatatttgtg tgtgggatag aacaatatta aatactaata aacatataaa aggatacaca
   108901 attattattg gtcatacacc aactcaaaac attaaagatt atgaaaaggc tgaaatatat
   108961 aaacaggaag gaattataaa tatagattgt ggagcatgtt ttgataatgg taaattggct
   109021 tgtttaagat tggatgatat gaaagaattt tatatttaag aggtgttata tggacatatt
   109081 aaaaatcagt tacaacaatc taaatgctat atcaaaaata tcagaagtat taagggatat
   109141 tgtaaatgag gacactttaa tagtatgtat aggtagtgat agagttttag ctgactcatt
   109201 agcccctatg attggcagta tactagaaaa atctactatt agaaataaaa tatttggagt
   109261 attaggagat tcaatacatg ctttaaattt agaacaaaaa atacaagcaa taaaaaataa
   109321 ttatccaaat tcaaatataa tagccattga tgcttgtata agtaaaattt cagataaagg
   109381 aacaattata attagcaata aacctgttaa accaggtttg ggggtagata agaagttact
   109441 agaagttggt gattattcaa tagttgggat tataggtaga aataaatatg atatatatga
   109501 tacttcagac cctgaactta tacttgattt agctgatgtt atatcgaaat ctttaatatc
   109561 tatattatta gaaaaagaag aaaggatgat tgtatgatac aggaagtcag acaagaaata
   109621 ctattaaaaa atggtttgat tttatataca ggtgatttgg tagaaataaa atacaaatca
   109681 gatgaagatg taatagaaca tacttgtaaa ggtaaaatta aagaagcaaa agaattattt
   109741 attaaattag atacaagtaa gaaatataaa acttctgaaa gaatgattta ttcttgggaa
   109801 ttaaaagaaa taaaaaaggt ggatgatgaa gatgaaaaag ataattaata gtaaatatag
   109861 agcattatat ttatttatat tttttctaat tttcaattta atatatagtt tatattttgg
   109921 aaggaatacg gagattggat tttattctag tacatcttgc atagaagaat atatactgga
   109981 tattataacc tctataggac tatttttctc aatgatgtta gctgggtttg atgttacaga
   110041 aaactttata aacagtttaa gggattattg tgaagaagat gcaaagtgag gtgaataaat
   110101 tggaattaaa ggattatata agtaaagtag aattaaatga catgccattg accttagaca
   110161 ataaatacat gttaaatgaa ataagcatat ctgaagatag caaaatcttt gctgtaaaag
   110221 acacatcagg aataacatct tattatactg aaatagaatt taataaacta tttagaggaa
   110281 ttaatagcat cctagagaat attatctaat atatattttt aaggaactga gggttgagag
   110341 ctattaatta atagctctct atttttttga aaggggagaa ttaatggaaa aggaactata
   110401 cagctttagt aaattaaatg catttaacac atgtccattt cagtactatc ttacatatgt
   110461 aaaaaattta aatcgagaac aaagttgtta cggttattat ggcaatgaat tacatagttt
   110521 actagaacaa ttacaacaaa gaaaaataac aaatcaagaa gctattcaaa aatacaatga
   110581 agttatagaa tatgcaaatc taatggatta caattttcct acaccaaatt caagaattaa
   110641 ttatttagaa tgtatattac attatataga aaattttgta ccaattgaat gtgatagata
   110701 ctatatagaa gaatattttg agtttgatat taatggaatt acaatgaggg gatatataga
   110761 cttatattat ataataggta ataaaattta tgttatagat tataaatcga gtagtaaatt
   110821 ttctaaaaaa gacctaccta aaaaatcaat gcagcttatc ttatatgcaa tgtatcttaa
   110881 agaaaaatat ccagataaaa taattgaata tgtagctttt gatatgtgta aatatatgaa
   110941 taatgaaaaa ggagtattaa ttgaaagaaa taagattgat agtataaatg attatgaaag
   111001 agctatagta aaaattaaat atactaaaga actagagaaa caattaattg attttgttgt
   111061 tgatacagtt actcaaataa aacagctaga ttccaacgat gagagcgttt ggtgcaaaag
   111121 tgatgacaaa agtaatcagt ttttttgtaa aactttatgc tctcattata acaagggttg
   111181 caaacataag gaaaacaaga gttttagaaa atcaaaatca taataaaatg tagattttaa
   111241 taagattgga gagtgtttaa atgaatatac caaagcaagt aaaagtagga ggtttattct
   111301 ataaaataga agagacagaa gaacctattt tagtaaataa tcaattatgt tatggattag
   111361 ctgattatgg aactgaaaca ataaaattat ctaataatct acaatcagaa agagtaaaag
   111421 aagctacttt cttacatgag ttattccatt gtatatttag agatagatgt atagagagtg
   111481 aagatgagga atatttagta gatgtattaa gcaagggact tcatcaagtg attattgata
   111541 atcctaatat atttgaactt aaggtgagta tagatggata aattaaaaaa tatatttgta
   111601 tttttaggtt attctggctc aggtaaagat agtatagtaa cagaaatttc aaagcaattc
   111661 aatattccaa ttctaatatc acatacaaca agacctcccc gtaattactt agaaatcatt
   111721 aataaaacct attattttgt agataataaa ttctttaaga aagaaaaaaa taactttata
   111781 gaaatgagaa agtatatagt tcatgatggc agcacttggc tatatggtat acataaatct
   111841 gaattagaga ataaaaaata tgctttgact atagtagatg caagtggata taaagcacta
   111901 gaaaaatatt ttacaggaac aaaaactaag ttagtaccat tttttataaa cgcagatgaa
   111961 gatactataa gaaaaagatt aatagataga ggtgataatc ttaaagaaat cgaaagaaga
   112021 ttagttgatg ataagattaa atttaaagag tttttaaata gtgaaaacta cattgtaata
   112081 gcaaataact taagtataac taatgcagta gagcaagtta aaatacatat gaaagagggg
   112141 attcaatggt cttagcctta gatgtatcca tgtcctcaac tggatgggca gttataaata
   112201 gaaataagaa tatattaaaa tatggaaaaa tagtaactaa aaaagataaa ttcaagtctg
   112261 aagatgagcg aatgtgttat atctgtaatg caattcaaga gttaattata actcataata
   112321 ttcaaatagt cttaattgaa gaccaattca cttcaagaaa ctctaaaaca attcttagtt
   112381 taagaaaact cttaggagca ataatgagga ctgtaaaatt aaataatata gagattgaat
   112441 atatgtatcc agtttctatt agaaaatatc tcctgaataa tggtaaagct aaaaaggaag
   112501 aagtagctgc atatgtaaga gaaaacatta ttgatattgg agaatatatt gataggactt
   112561 gtaaggctaa aacaagtgat atatatgatg ctatagcact tggaatagct tatttaaaca
   112621 aacttgatac taatagataa ttttaaaaag ggagattaaa ttaatgagta taaatgttaa
   112681 aataaagaaa ttaaatcaaa atgcaatagt gccatcttat gcaaaagaag gtgatagtgg
   112741 aatagattta tatacactaa aagatacggt gattccagct aaatcagcag tagcaatatc
   112801 tacaggtata tcattagaaa ttccatatgg atatgaaatg caagtcagac ctagaagtgg
   112861 tataagctta aaaggaatgt tttttacaag atatgtgact atatatgata aagtgcaacc
   112921 taaaaaacaa attagaaaaa tttttgtagc acatccaact gtaagattag gtacagtgga
   112981 ttcaggatat agaggtgaaa ttaaaataat tacatataat gaagaggatt ttgatatttt
   113041 aattcctaaa catactaaac ttgcacaagg agtatttcaa caagttccaa gagctatatt
   113101 aaaagtggta gatgaattga ctagctctga aagaggaagt aatggatttg gaagtacagg
   113161 tatatagatg aataagtata taatcctaga aaaatataat tattactatg atgacaaatg
   113221 tatgacatta tatcatttag aaaatatcta tacaggatta agattttcta ttgaaaaaat
   113281 tgaattagag tactataata tatcctagac taactttggg aggagtatta aatgtacaga
   113341 tatgatgatt atgtaaattt aataaatgac ttagaattac caaaagaaat taggaataaa
   113401 tgtgttagag ttataatgac actagagaac atgcaggata ttatggtagt acataagttt
   113461 aagacttatg ttgttaatga aaaatatatt gaaaaagtag cataaaataa ttaagtcatc
   113521 tattaattta ggtgactttt ttgcatttat gtcgaatatt tcatctactt catattgtat
   113581 tagatgctat aattaaaata tatgtcgaaa ggtagatggt gaggatgttt aaggagatat
   113641 ttgaaaaggt atttatgtca gaagaagtta gtaaaactgt aaaagaagtt aataatatta
   113701 ttaaggatac taagatacaa gtaaaaggtg gatttggaga acttagatta gattttatac
   113761 ttagcagatt aggcaaagat tacataataa ttaaagacat tattgtacca ggctcaaata
   113821 agactacaca aattgatagt attgtgattt ctatgtatgg aatatttgtt atagaatgta
   113881 aaaattttag tggatatatt tacggaaatg ataaagataa agtatggact caaattgtag
   113941 gaaaaactaa aaatacattc tataatccgg taagacaaaa ttatgctcat attaaagcaa
   114001 tagaaaatat aataggaaat aaatataata tatattcaat aattgttttt tcagacaaag
   114061 ctacactaaa aaatgtaatg ataagtggaa ataatattat agttataaat gaaagtgaga
   114121 tattaagtac aataagtaaa tgtaaagatg tgactattga taaagaagaa ataaaaatta
   114181 tcagagataa aatttttgat tgtatgaaaa ccactaatca aaatactaga gagcatgtta
   114241 gaaatttaaa aaatattact gaagaggata agtgccctag atgtcaaatt ggacatttga
   114301 ttaaaagaaa aggtcagtat ggtgaatttt ggggatgtag tcagtatcca aaatgtaaat
   114361 acactagaaa ataaaaaaca acctcttaaa ttcgatttta aggctttgta aaaattaatg
   114421 cttataatta atcctgttcg gaaaatcgat tgcttaaaat ggaaaatata taaaaataat
   114481 agcgtgatag tgtaaggcat agaattgtgt attctatgtc ttatttcttt acaactaagt
   114541 aatttcaata attatataaa taaaagaatt aaaaaagtca gttgaaagtc agctaaaatg
   114601 actatttttt gcctcctctg tatggtataa taagtatatg aattttcata ggagggataa
   114661 ccatgaacgc ttttataaga aaaagaaata aaaattatgt agtgtactta gaatttagag
   114721 atgatgaatc aggaaaaaga aaacaaaaaa atatgggagc atttgataaa aaaagagatg
   114781 ctaataaaag attggctgaa gttaaggaca gtatatataa agatagtttt cttgtgccaa
   114841 atgaaatcac tctagctgga tttttattag actttcttga aaaatataaa gataatattt
   114901 cagcatctac atataaaagc tatattgcta tttgtaaaaa tcatattaat ccttctattg
   114961 gaaaatatcg tcttcaagag ttgagaaata ttcatataca gaattatata gatgatttag
   115021 ctggtaactt aaaccctcaa actattaaag tacatataaa tgtattgaga cttgcaataa
   115081 agagagctta tagaattaaa ttaataaaag aaaatattat agatggaata gaaagtccaa
   115141 gaattaaaaa atttaaaaat gaaatttatg ataaagagca gatgctaaaa ttattagaag
   115201 tagctaaagg aactaatctt gagcttccta ttagtttggc tataggtcta ggattgagac
   115261 tttcagaagt tttgggatta acttgggata atattgattt tgatgaaaat acaataacag
   115321 taaataagat aactagtaga ttagatggtt ctgttatact taaagagcca aagacagaaa
   115381 gctctgttag aaaaatattt gcaccaatag agcttatgaa tttactaaaa aattataggc
   115441 tggagcagaa taagaagtta ttgagaagta ttgttagaaa tgaatataac ttactatttt
   115501 ttgatagaaa agggaatcca attgctgaag atgtaatgag taagaaattt agaaaattct
   115561 tagagaataa tgacttgcct catattagat ttcatgactt aagacattcg cacgttactt
   115621 tacttataaa ttctaaagta cctataaaag ttatatctga aagggtagga cattcaaata
   115681 ttaatactac tcttaatgta tattctcatg tacttaaaga aatggacaaa gaagcttctg
   115741 atagaatatc tgaaaactta tttaaggcta attaataatt atcatcaata aatacaaaat
   115801 taataataaa agcaaaggta taaacataaa ggggaatttt tacaaagcct tagaatggca
   115861 tatagagcgt cagattttag aagatattaa aattttatat ttccaatatt tatgatataa
   115921 taaacatagc aaggaataaa tatttgaaaa aagctgtgag tggtgtttcc atagaaattt
   115981 cctcactttc ttatgaaagg aggtgaaaac tatggaaaat ctaatgatga gtattatagc
   116041 tggtgttata gctagttata tctacgataa attaaaatgc cactctgagc gaccaactaa
   116101 gagtggctgg gaacttaata ttaagttcca taaaaacaaa cattaataac taattaatgg
   116161 aaacatcact caaagttaag taaaatatgt ttccttgctt ttattatacc acaaattaag
   116221 aatattaaaa caaaattttg taaatacata cttaattatc aatttaatca tttggaaaaa
   116281 attggatttg attgtatgaa attattgctg taatatttaa attaaataaa caaatgatgg
   116341 gagagataat tatgtattta agaaaattat caaagtcaga attaattgta atgaaattta
   116401 tatggaattt agatacaaaa gtaaaatcat atcaaatcat taattatatg aaagaaaaat
   116461 atagttggtc agaaaaaaca acattaaaaa ctttatctaa gttatcaaat aaaaggttca
   116521 tatatgttca agaaacaagt caatgtacat actatacaat ttcaattaaa gaagataagt
   116581 atcatgaatt tatatcacaa aaaatacata agctcttagg gtgcaattct ataaaaagcc
   116641 ttttagcatc attgtttcaa gaagaattaa cagatgaaaa aataacttca ttggaagaat
   116701 gggtaaaaaa ctgggaagaa gaggaataaa gataatatat actattcctt aaaaatctat
   116761 ttaaagaata attgaaattt tgattttaat ataatttctt taatcaactc taacatacaa
   116821 aaataagact cttttcaata ttaactaaag agccttattt tataattgat tatattttag
   116881 ttaacttttg tgtatcaaaa ctatactcat atacttctaa tgtttcagaa tttacaatta
   116941 gagttcctac tgttttaatg ctatcttctt tatcagtata agtatcagaa ccatcagtgc
   117001 tagattcatc ttgtttaaca tttttaacac tgattatttc aaactcatag tgtggaaaat
   117061 ctatattttc agctttttta tatcttgagt taccataatt atatgtataa caatattcat
   117121 gtgcttttga accttttgct ttatatatag catctaaagc ttttgagatg tcacttcttt
   117181 tagtattacc agttaacata taatctggag ttaagcattg gtctaaaatt tcatttttta
   117241 tatcacctat tattattggg aaattagcac tagtaactaa tgatttgtca ttagtttcat
   117301 ttactaaaaa tacaggatat tctttgtgta ttgtagaaga taatagtgca tctattaaat
   117361 tatcagaact tacaatacat atttgatttg gatgttttaa ttcatcttta taaaaatgct
   117421 taattatttt ttcattagtg tcaagtctat caacaccacc aattctagtt gcttttgtac
   117481 tgttcactaa agagtcgttt attgatgctg ttcctccaat agcatatgtt tttaccccat
   117541 ctgttttaaa tggtatattc tttccatttg ttaatacaac tggattttta tatttagcag
   117601 caactggaga tatacttata gaatcagctt ctccttgata agcatttgta aaatatactt
   117661 catcaacctt ttttagataa cttatctctt ttgcaacatt gtaacttgtg tcgattctgt
   117721 ctttgccttc tatcctaata acctttattt ttttgttttt tagtatattt tctacatttt
   117781 tgcttataga attaactccg cctattaaat agattttttt aaatttatct aatcttttaa
   117841 gagtagaatt tggtatagaa ttttgtttag taagtaatat cggcgagtta gaagctccag
   117901 ctaaaccact tgcacttaat ccatctgcaa gacttttatc tgtatttata attattgctt
   117961 gagtgtactt tcttctgtca gctattaaac ctgctgtttc atacttattt gctccttgta
   118021 ttctatgagc tggacgtcta aattttagtt ctttagctga aactaataat gtactagaca
   118081 tgacaataga aaatattata gctaaggtta atacttttct tttgaatttc atattgtaaa
   118141 atcctcccat ccttttatac tataaatggt agtgtatatt gttttagttg tcaactctct
   118201 ctacatactt tgttgtatta taatttataa gttgatattt tgtaaaaata aggatattat
   118261 ttaagtagaa tataattact atttttacaa ggaggttgtg atttgagtag gtattctcct
   118321 caaacaaaat attttgaaat agcagttaag tttaaaaaag ttaacacatt tttattttgg
   118381 gtatttttta ttttatcaat aatattcacc tttcaaaata ataataattt aataacttgt
   118441 tttagtatta tctctcttat aatactaaac atgcttgata tctttatttg taactatcaa
   118501 gaaaaaggag aatctaagag aaggaatgat tttattgaca actcatttga ttgtaaatat
   118561 tctacacata actcaataga atattatgat aatgatgaaa tacattatgg attatataaa
   118621 gctcttgtca atgtatatca aaatgctttt ttctctaaag aaattttatc ttatacaaga
   118681 aaatttataa taataaaaaa tgtaatacca tgtatgataa tagttatatt ttcatttata
   118741 ggattctcaa atagtaattt tgctttgcct atattgcaat tatttttctc aaaatatttt
   118801 atattagact taataaatac ttctggatat ttaaaaaatg tagaatcggt atttgatagc
   118861 ataacagata tgtttgagac tggtctggtt gcaaaaaaag ataacaaggt agaatctaaa
   118921 ataataaaag ttttaataaa ctatgaaact aatatctcta gttcaaagat atttttaaat
   118981 tctaaagtat ataaaaaaat gaaccctgaa ttaacaggag aatgggataa aataaaaaaa
   119041 agatataata taaaagaggt gtcaaatatt tgagtgtaaa tagttattta gaaaatctat
   119101 ctcatgaatt aataataaga gataatgaaa aggaaaatat aaaaaaatca atagaagtta
   119161 ttaagagtag gttaaaatca tattttggaa acaatattgt agaaacattt tgttttggct
   119221 cttataccag aggaactatg ctgcctagaa aagtaaatga aaattcggat gtagattaca
   119281 tggtagtttt ttcaaatagt tttttatatg ctccacagac tttactaaat aaacttagag
   119341 attttgtgag aacatattac tctaagtctg aaatatacca gtctaatcca acaatagtct
   119401 tagagttgaa tcatataaaa tttgaattag ttccagcata ttctaataat atgtatcttt
   119461 ggcaagaaaa tcactataga atacctgcaa aagcctctaa ttataacgac tggatagata
   119521 catgtccaga tgatattaat agtagattga ctagactaaa tgttgaatca aataataaat
   119581 taaaacctgc aatacgaata attaaatatt ggaattcttt aaacaataat gtttatagtt
   119641 catatgaact tgaaagtgca attttagaaa atatgcattg ttattggaga acatctattc
   119701 aggattattt tacagctata acagaatctt taatttataa tttcggtaca ccatcatgga
   119761 aggttgataa aatctcttct cttaaaaaat ggtataatca tgcattaaaa gaagaatata
   119821 tttggagaaa ttatatacaa tctaatttat atatggaaaa tattttacct tcaataaaat
   119881 aaaatatagt attatagata gacaaaaaaa ataaagccct ttaaagaaaa ctcatttaag
   119941 agtaatcctt aaagggctta ttagctatct ctttttctta ccttttttgc tacctttaca
   120001 tgccatgata ccacttcctt tcaatttaca taaacttatc atattcctca gctaatttat
   120061 ttttattttc tattgtgtag tgatttatag ttacatcaac cccactgtgg ccaagcaatt
   120121 ttgaaactgt agttattgga actcctctgt cttttaaaag attagacata ctatgtctaa
   120181 ggtcatgatt atatccacct tctataccaa ttaacctgaa agctttttta acccatgaac
   120241 ttaagacatt tgaattgact tgattgtatt tgcctccata tcttgtaaag aatatatacg
   120301 gataatctat attattttga gatagataat ccttccattc tattaataga tgctggactt
   120361 cttctgaaaa tctaaaatct cttgaaactc cacctttggc tgtaatacca tgaatccatc
   120421 tattatctaa atctatattg tcccatctaa attgacttat ctcattactt ctagccattg
   120481 tagccaatcc taaatttata taaacttcta actgtaaatt gtcttgctct gaaagctttt
   120541 cttttaattt gcttaactgt tcttcagtta aaaaagttct tttctgaact tcttcgcctg
   120601 ttcctggtct ttctatcatt tcacaccagt tgtcagtaat tttcctcttc ttctttaaaa
   120661 aggatagtaa tgatgaaatt gaacttattc tacgtctaat tcttttttca ttatttccat
   120721 gttccataca ataacctata taagcttcta tttcttcttc atttatatca gttagtaatg
   120781 catcaaaaca ttctatattt aaaaacttaa aaaattgcat tatatcacat tcataattat
   120841 atattgtttt ttcacttttc ccagctattt gttttgctct tttgtattgc ttccataatt
   120901 taatattctc tggatttagt tctccattta tgcttattct tttactgcgt tgttttgcca
   120961 aatacttcac ttccttataa aaaagactag agaaattaat ctctagtctc taatttatct
   121021 ttaatttttg ttatgtctgt ttcaactctt tcaagtctac tgttattagt atttaatgct
   121081 tcagcaaatt tatctaattt atcatcaaac ttatctattg tattaccaaa taaagttctc
   121141 tgctctttaa tttctcttga aaaataagct ctttcttttt ttctatcatc ctgctctagt
   121201 tgtctattct tttctaaata tctgccaaac cataacatta ctactgtaag tagtatggct
   121261 gtatatccat attggcttaa taattcaatc atttctttag ataacatcta cttttccttt
   121321 ctgttttgta cttgtatttg atttattcct atagatgctc cccaacataa aataccttca
   121381 aaaacagctt ctattgacag ctctttcata aacaaacaac tgcttatcat tgctataact
   121441 aacaatataa aaggtatgta tttattttta atattagatt cttttataaa tgttcctaat
   121501 atgtaaagcc cacctattaa cattattaaa ttttcaggta taaattgcat tatatccatg
   121561 tgatttcctc ctatccaaga atctcattta attcttttac tttagttttt atttgctcta
   121621 attttacatc attgttttct accttcattg aacttatctt attacatata tttattatgt
   121681 tttggccata attcatatct ggacaccatt tgcctgataa actttctact gttttagctt
   121741 ctccatgtaa atatggaaaa tgtctagggt ctaatgtagt tccatttact ttatattcaa
   121801 ctttaccaac taattcacta tattttggat atcccttagc tccagcatat aatgctagat
   121861 ggtcaataaa tgctgatact ccatcctccc aacaattaaa tcttgtatga gctgttgggt
   121921 ctaaatctcc tccaccttta tttcctttaa gaccacacac attgcaataa gaaggattta
   121981 aaactctacc aaaattaaaa tatccagttt ctacaaatgc ttgagcaatt gcaataactg
   122041 gatttacacc ttttttctct gcttctttat atataattgg tactatagct ctgcataaaa
   122101 aatgtggtgg attagagtta ttttttaatg tgtctaaata cgaaaagact tgttctaatg
   122161 tagctgttga tttatctaat atattcaatt cattacctcc tacttgccta taaaatctaa
   122221 cactttatga agtgtagccc atctatcatc accttgtaac ttagtgaatc tctcgctagt
   122281 tttaatttta ctggatgctc caccaatcac atataggttt tcacaatgtc caggaacata
   122341 attttccaaa tcacacacag agacttcatt agtcttataa ttcatggcca ttaattgggc
   122401 tataacttta tctacctcac cctcataaac tattgcatat ttcactttgt tatcttgtgg
   122461 tttaccagct acagacttat taaatattcc ttcataaata tctatggcca tatctttagc
   122521 attatatttt ttagtatcag atgtgtctac aaaacagcac tcaactaaaa ttgactttgc
   122581 cttcgttctt cttaaaaatg ctagagtttt cttttcttta actccacgat ttttaaaatc
   122641 tttatcacct tttgcatgat aagtttcagt tattttttta catattcttg atgctatttc
   122701 aacagtttct ttgtcattta aattataaac taaaacttct actcctcgac caccaccact
   122761 gttaaaatgg atacttacat ttaaatctgt gttatatgaa ttacatttat ctataatctt
   122821 attcaatata tcactctgag aagttccatt gttacatgta caatcataaa ctttacattc
   122881 cttttgagat aaaggtatta actcttttag tacatttctt gcttctgtag attcttttat
   122941 atttcctact gctccagaac ctactttacc atctgggttg tgtcctgcat gaactgtcag
   123001 tgtttttata ttcaaaatta ccactccttt aaaacaatta atataaaaag agtctataaa
   123061 ataaggctct tatttactca atttctaatt aaaattatga ttttaatctg ttttgtacat
   123121 taaaaaagac tatactatgt agtcctctcc tgttatttct ttatattcac ttgctgttat
   123181 cttattcttt tctactgctg ttttaacttg ctctttagtc caattaccat tattatagaa
   123241 atctgttatt atcttatacc aattcatact atatcacccc attactcatt aattgaaatg
   123301 ttaaatctgc tattgtttgt tctgtagaat ttactttatc ttctatgcta cttttaatat
   123361 ctgtatatct atagaaaacc tctttagtat ctatatttat aaataacttt gcttctttat
   123421 tttctacata ttgttgtact ggcaatttct caattaaaat tccatttttt aactcttctt
   123481 ctgatagtaa agttggttta tagtgtatca tcccaatata ttttatattt tgttcatctg
   123541 tctccataaa atttcctaaa taaatcataa ttcctctcct ttttcatctg aataaacctt
   123601 ttttgataat atatttctgt gaatgccacc accaataaaa aaaattatat tgtttattat
   123661 aaacatacct ttttgaggat ttgtgttaat gagcgttcgg tagctattaa cttctttaag
   123721 agtatttaaa tttattttta taaatgggct actagaaagt gaattaaatg tatatatata
   123781 tccattatat atttcaaaat tttcatatct atctgaccca ccataagtaa tcaaatttag
   123841 atttgcatca tattttgcta atccactttt tttaccactc tcaacttcta tgcttctgcc
   123901 actatcagat acaaaaacaa aatcatttaa aaacttaat
//
LOCUS       DAYAOO010000002        99010 bp    DNA     linear   BCT 12-OCT-2024
DEFINITION  TPA_asm: Clostridioides difficile isolate ST8-SSI-h139-18
            SAMN40601845-rid21577343.denovo.002, whole genome shotgun sequence.
ACCESSION   DAYAOO010000002 DAYAOO010000000
VERSION     DAYAOO010000002.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN40601845
            Sequence Read Archive: SRR28438827
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 99010)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 99010)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-MAY-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-MAY-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002157583.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002157583.1
            Genome Coverage       :: 163x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/11/2024 16:19:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 4,038
            CDSs (total)                      :: 3,963
            Genes (coding)                    :: 3,930
            CDSs (with protein)               :: 3,930
            Genes (RNA)                       :: 75
            rRNAs                             :: 6, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 60
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 33
            CDSs (without protein)            :: 33
            Pseudo Genes (ambiguous residues) :: 0 of 33
            Pseudo Genes (frameshifted)       :: 7 of 33
            Pseudo Genes (incomplete)         :: 25 of 33
            Pseudo Genes (internal stop)      :: 11 of 33
            Pseudo Genes (multiple problems)  :: 8 of 33
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..99010
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN40601845-rid21577343.denovo.002"
                     /isolate="ST8-SSI-h139-18"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Denmark"
                     /collection_date="2018"
                     /collected_by="Statens Serum Institute"
     gene            342..875
                     /gene="pyrR"
                     /locus_tag="ACGI5H_000162"
     CDS             342..875
                     /gene="pyrR"
                     /locus_tag="ACGI5H_000162"
                     /EC_number="2.4.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003431186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0009116 - nucleoside metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional pyr operon transcriptional
                     regulator/uracil phosphoribosyltransferase PyrR"
                     /protein_id="HFG9695896.1"
                     /translation="MVEKAQLMDEKAIARAITRISHEIIERNKGVENLVLVGIKTRGV
                     PIANRISKKIEQIEGTKVDTGDIDITLYRDDLEKIHVEPVVKGTYLDFNVNDKTVVLV
                     DDVLYTGRTVRASLDAIIDIGRPKSIQLAVLVDRGHRELPIRADYVGKNVPTSRHEII
                     SVSLLEIDGEDSVTIKE"
     gene            1159..2370
                     /locus_tag="ACGI5H_000163"
     CDS             1159..2370
                     /locus_tag="ACGI5H_000163"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729399.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="solute carrier family 23 protein"
                     /protein_id="HFG9695897.1"
                     /translation="MKKTIMSLQHLLAMFGATVLVPILTGFNPSVAIFCAGVGTLIFH
                     FCTEGKVPAFLGSSFAFIPVILAAKEAYGGDLAYAQGGIIVAGLIYIIMSIIVKVVGV
                     NKIKLYFPAQVTGAMIVVIGLNLLPTAFSMASANFVIAFITLAIAILTNKFGRGFIKQ
                     LGILIAVFSGYIICLILRLVDITTITEASLFAIPNFTVPKFSLGAIVIISPVVLAVFM
                     EHIGDMTTNGAVVGKNFIENPGLNRTLLGDGFATIVAGCLGGPANTTYGENTAVLAIT
                     KNYDPSILRRTAIFAILLACVGKFGGFLQSIPGSVMGGISIMLFSMITYVGLKTIRDS
                     SCVESKINILIIAVILLIGLGTTYLSNKGISVGIPITSTVKITGLSLAAIVGIVLNRI
                     LNNQDFKVEEE"
     gene            2669..4321
                     /gene="cplR"
                     /locus_tag="ACGI5H_000164"
     CDS             2669..4321
                     /gene="cplR"
                     /locus_tag="ACGI5H_000164"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861613.1"
                     /note="Contributes to intrinsic pleuromutilin, lincosamide
                     and streptogramin A resistance; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F type ribosomal protection protein CplR"
                     /protein_id="HFG9695898.1"
                     /translation="MLLVKVENLKKYYADKLILDIDKLEILENDKIGLVGSNGQGKTT
                     LLKAILGEIEIDEGYTYLTESYSYISQSENNIETCSHSKEKSLLNAPDKFEEHLSGGE
                     KVKLKIADALSNKKNIIIADEPTSNLDKKSIGVLEDMFKRHEGALLLISHDRRFLDEL
                     CTTILELEDGKLKAYKGNYTDYLMQKDEEVKRADFEYQEYVKEKKRLEKALLYKKALS
                     DGIRKTPKRMGNSEARLHKMGGQTNKKKLDSNVKAIKSRIDKLEVKNKPKVSKEMNIK
                     IQDGMEIISKNLVEVKDMTLKLENKLLLDNVSFKIKRGKKIALLGDNGCGKSTLIKEI
                     LADKNDNIKINNKVKVGYFDQNQSLLDEEKSVLYNTKVNSSFDESFIRINLSLFGFKG
                     DDVYKKVKVLSGGEKVKIALCKIILEDNNFLVFDEPTNYLDIKSMEALEKALINTDKT
                     MLIVSHDRVFVSHICNYIIEIKDAKIREFDCNYDEYTISRNKKTPSRENQIKKENLLV
                     LENRLTTVISMLSIEKDNLKKELYESEYNELLKQINKLKNSF"
     gene            complement(4536..6311)
                     /locus_tag="ACGI5H_000165"
     CDS             complement(4536..6311)
                     /locus_tag="ACGI5H_000165"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897789.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NFACT RNA binding domain-containing protein"
                     /protein_id="HFG9695899.1"
                     /translation="MALDGLVIHSIVDELSSKLTGGKIDKIHQPEDDEVIFNIRNNKE
                     NFRLVLSASASNPRVYLTSNYQKENPLKAPMFCMLLRKYIQGGNIVEISQIGFERIIK
                     ISVESLDELKEKTVKNIMIEIMGRHSNIIITHGEENKIIDSIKRVPFSISRVRQVLPG
                     HDYSLPPEQNKLNPLDDISKDLFIKNLEELEGPIFKSIYSKFLGISPIIAKEICYRAG
                     VNQNAIIKDISDEQFDSLHKVFCNLFNDINSNKYSPCIIIDKKVDKVVDFSCINLTLF
                     SDLSYINKDSMSRILEDFYRTKDIKDRINQRSSDLKKSISVKLDRLYNKLKKQEEELS
                     ESENADIYKIKGELITSYIYMVEKGMESIEVANFYDENCNDVTIELNKNLTPSENAQK
                     YFKKYNKMKHAKVEISHQISLNKEEIDYLENIILSIENCENLAELQDIKEELAKVGYI
                     KTQKKNSKKDTIPSTKPHEFVSSDGFKILVGKNNKQNDYLTLRLADNDDLWMHTKNIP
                     GSHVIIKCAGKEVPDNTVFEGAMLAAFFSKSKLSSQVPVDYTKRKNVKKPSGSKPGMV
                     IYETNSTIYVTPEEETVAKLKVKSE"
     gene            6607..7641
                     /gene="ltaE"
                     /locus_tag="ACGI5H_000166"
     CDS             6607..7641
                     /gene="ltaE"
                     /locus_tag="ACGI5H_000166"
                     /EC_number="4.1.2.48"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454904.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016829 - lyase activity [Evidence IEA];
                     GO_process: GO:0006520 - amino acid metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="low-specificity L-threonine aldolase"
                     /protein_id="HFG9695900.1"
                     /translation="MRFIDLRSDTVTMPTDEMREAMAKAPVGDSIFRDDPTVNKLEEL
                     AAAKVGKEDAIFLPSGTFGNQLALFTHCLRGQEIIIGKGYHIVTHEVGAPAVIAGVQL
                     RTIDEDESGALNPELVEKAIRRDDIHEPQTGLICVENAYSGGTVVSLDNLREIKKIAE
                     KHNLPVHLDGARLFNAALTLGVEAKEIAKCCDSVMFCVSKGLAAPMGSILAGNKEFIA
                     KARRKQKVMGGGMRQVGIVAAAGIIAIEKMTLRLNEDHENAKYLACELNKIDGIEVNN
                     VNPDISMVFFKMSEDIIKEDVLIKEFFERNIKINKMENGEYRFVTHVDITKEDLDYVL
                     KTLKELIGVC"
     gene            7928..8758
                     /gene="dapF"
                     /locus_tag="ACGI5H_000167"
     CDS             7928..8758
                     /gene="dapF"
                     /locus_tag="ACGI5H_000167"
                     /EC_number="5.1.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897787.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008837 - diaminopimelate epimerase
                     activity [Evidence IEA];
                     GO_process: GO:0009089 - lysine biosynthetic process via
                     diaminopimelate [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="diaminopimelate epimerase"
                     /protein_id="HFG9695901.1"
                     /translation="MKFWKLHGIGNDFIAIDGRFDQINPSDYTALAKKVCHRRFSVGA
                     DGLLVVKDSKVADVEMVYYNSDGSRAAMCGNGLRCFCKFVYDNCIVKKESFTVDTLDG
                     IKDIKVNLTNREINSIRVNMGKGSFIAKDVPVLTNKERFVQESIKVLDRELKVTSMLM
                     GVPHTVVIVDELDVDDVCKYGKEIENNKIFPEKTNVNFVKVEDKYNIHVYTWERGCGY
                     TLGCGTGMTASAIVCNLLNMVESSVNVTSQGGTVKIDVGDFSYMTGPAVKICEGILEV
                     "
     gene            8762..9643
                     /locus_tag="ACGI5H_000168"
     CDS             8762..9643
                     /locus_tag="ACGI5H_000168"
                     /EC_number="3.1.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903268.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016788 - hydrolase activity, acting on
                     ester bonds [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="YicC/YloC family endoribonuclease"
                     /protein_id="HFG9695902.1"
                     /translation="MAISMTGFGRGEYKDDNYYFLVECKTINHKYSDINIRLPRKISF
                     LEDKVRNLVKNYVKRGRVDLYIKFDLLGKEDVNLNFDEGLASQYIDILKEIKNKFDII
                     DDISVMNVAKFPDIVKIEEKEEDEDLLWSMLNQAVEDALIKLREMRSEEGKKLAEDIA
                     MRCDLLKNHIEEIEKYSSSVVEDYREKLNLRISELLDDPSIIDENRLAQEVAIYADKS
                     SITEEIVRFKSHIGQLKNTIFKDDSIGRKIDFLIQEMNRETNTIGSKSSDINITNLVV
                     EVKSELEKIREQIQNIE"
     gene            9673..10290
                     /gene="gmk"
                     /locus_tag="ACGI5H_000169"
     CDS             9673..10290
                     /gene="gmk"
                     /locus_tag="ACGI5H_000169"
                     /EC_number="2.7.4.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003431170.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004385 - guanylate kinase activity
                     [Evidence IEA];
                     GO_process: GO:0006163 - purine nucleotide metabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="guanylate kinase"
                     /protein_id="HFG9695903.1"
                     /translation="MFVKKGLLLVVSGPSGAGKGTICKELLKENDTIKLSVSATTRKP
                     RTGEVDGVNYFFISKEKFEEMIEKGEFLEYAQIYDNFYGTPKAAIMECLEKGQDVLLE
                     IEMQGAKQIKEVCPEGVFIFVLPPSLKELKNRIVGRGTETEAEIEKRFSCAYEEIKMI
                     KDYDYFIFNEDVKTSAKEIEGIISSEKNKVSRYKNIIIEKFKEEL"
     gene            10293..10559
                     /gene="rpoZ"
                     /locus_tag="ACGI5H_000170"
     CDS             10293..10559
                     /gene="rpoZ"
                     /locus_tag="ACGI5H_000170"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416246.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003899 - DNA-directed 5'-3' RNA
                     polymerase activity [Evidence IEA];
                     GO_process: GO:0006351 - DNA-templated transcription
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit omega"
                     /protein_id="HFG9695904.1"
                     /translation="MLKPSINEVLEKIDNRYYLVGTVSKRARKLIDGEEPYVSNKTKE
                     KPVCVATKEVASGKITYRLLTEEEIEIEEARHHAEQHQQISEEE"
     gene            10564..11763
                     /gene="coaBC"
                     /locus_tag="ACGI5H_000171"
     CDS             10564..11763
                     /gene="coaBC"
                     /locus_tag="ACGI5H_000171"
                     /EC_number="4.1.1.36"
                     /EC_number="6.3.2.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890797.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004632 - phosphopantothenate--cysteine
                     ligase activity [Evidence IEA];
                     GO_function: GO:0004633 - phosphopantothenoylcysteine
                     decarboxylase activity [Evidence IEA];
                     GO_function: GO:0010181 - FMN binding [Evidence IEA];
                     GO_process: GO:0015937 - coenzyme A biosynthetic process
                     [Evidence IEA];
                     GO_process: GO:0015941 - pantothenate catabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional phosphopantothenoylcysteine
                     decarboxylase/phosphopantothenate--cysteine ligase CoaBC"
                     /protein_id="HFG9695905.1"
                     /translation="MLKDKTVVIGISGGIAAYKACDVVSKLKKLNANIHVIMTKSATE
                     FVKPLTFQSLSQNYVVEDMFEEPKTWEVEHISLAKKADLFLIVPASANVIGKIANGIA
                     DDMLTTTVMATKAQVLIAPAMNTNMYENPIVQKNIQTLKSFGYKFIEPESGRLACGDI
                     GTGKLANPDIIVEEVLTNLTKEQDLKGQSMIVTAGPTVESIDPVRYLTNRSSGKMGYS
                     IAREAIARGADVTLISGPTNLSIPQNLKKFVQIESAQDLYEAVVSNLSENKIVIQSAA
                     VADYKPKTYSDKKIKKKNDDLSIELSRNYDIAYEIGKIKEDKILIGFAAETNDLIEHA
                     KGKIKKKNLDFIVANDLTKEGAGFRADTNIVKIIDVEGNITEYPKMKKEEVANVILDK
                     VKALLEK"
     gene            12038..14527
                     /gene="priA"
                     /locus_tag="ACGI5H_000172"
     CDS             12038..14527
                     /gene="priA"
                     /locus_tag="ACGI5H_000172"
                     /EC_number="3.6.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897784.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003678 - DNA helicase activity [Evidence
                     IEA];
                     GO_process: GO:0006260 - DNA replication [Evidence IEA];
                     GO_process: GO:0032508 - DNA duplex unwinding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="primosomal protein N'"
                     /protein_id="HFG9695906.1"
                     /translation="MKKYAKVIVRSNTIYTDNLFTYQIPVFLSDVIKIGHRILVPFGK
                     GNKPTEAFVFQFTDSLDEKIKIKEIIDILDENPIFRKEDLELVYWMKNRYLCTYIECI
                     NLIYPKGYKLNNYKVVLLGESLSGLNDIELKEKISTLSDKNREIVEKVIDSKGKIKVD
                     KLKYIPNLNSSLYTMNKNGIIKLCWEYKNHKNEKKVCYISLSLESDKIDDYIEQNKIN
                     VGSKQKEILSFLKNNENVEINDLLDLLNASKQSINSLSKKKLITLEFKDYYREPKSIY
                     KSVLKSIKLNNEQQEAVDEIKSNMFVDDKKPYLIHGVTGSGKTEVYMEIIEFALNQGL
                     DSIFLVPEIALTPQTIDRLKSRFGDLVGVFHSKLSEGEKHDVYKAVKAGKVRVLIGAR
                     SALFAPFNSLGLIIIDECHESSYKSEKNPKFNAIEVARFMALKNNITLILGSATPSIE
                     EYYRAKSGEYKLINIKSRANDKPLPNIEVVDMKDELDKGNRSIFSLKLQKEIRYAIEE
                     NNQVILFLNRRGYANFVSCRKCGYVFQCENCDISLTYHKKSNTGRCHYCGYEKEIPKE
                     CPECKSTYVKPFGVGTQKIEEELKYIFPDIKTLRMDKDTTSKKGALDEILNKFKDKEA
                     DVLIGTQMLSKGLDFENVTLVGILSADMILNFPDFKSFETTFQLITQVSGRAGRADKE
                     GKVVLQTYDTEHYAIKHAIEYDYEGFYEDEIKIRKAFGYSPFNNMLSVVVSGEDERLV
                     IKNIKNMHASLIYLLEKRGINDLGFILGPNPCSISKINQNYRWQILFKDENIEINLLK
                     GIIKYICITKRDLIFDKNINVSIDINPNSVL"
     gene            14545..14985
                     /gene="def"
                     /locus_tag="ACGI5H_000173"
     CDS             14545..14985
                     /gene="def"
                     /locus_tag="ACGI5H_000173"
                     /EC_number="3.5.1.88"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003431159.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042586 - peptide deformylase activity
                     [Evidence IEA];
                     GO_process: GO:0036211 - protein modification process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="peptide deformylase"
                     /protein_id="HFG9695907.1"
                     /translation="MALRQIVQIGEPVLRKKSKKVEKIDEKIIQLLDDMAETMYDADG
                     VGLAAPQVGILKRVVVIDIGEELIELINPEIIETSGEQIDEEGCLSVVGEAGNVRRPN
                     YVKVRALNRNGETIELEGEELLARAFCHEIDHLDGILFVDKIEK"
     gene            15000..15929
                     /gene="fmt"
                     /locus_tag="ACGI5H_000174"
     CDS             15000..15929
                     /gene="fmt"
                     /locus_tag="ACGI5H_000174"
                     /EC_number="2.1.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861609.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0004479 - methionyl-tRNA formyltransferase
                     activity [Evidence IEA];
                     GO_process: GO:0071951 - conversion of methionyl-tRNA to
                     N-formyl-methionyl-tRNA [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="methionyl-tRNA formyltransferase"
                     /protein_id="HFG9695908.1"
                     /translation="MKIVFMGTPDIAVPCLQKIIDEKYEILGVVTQPDKPKGRGKKLG
                     MSPVKELAIENNIPVYQPVKARDKEFIDKIKSLNPDVIVVVAFGQILPKEILEIPKLG
                     CINVHVSLLPKYRGAAPINWVIINGEEKTGVTTMYMDEGLDTGDMILKTEVNLDENIT
                     AGELHDKMMNIGAETLKETLRLIEEGNAPREVQNHEEFSYAPIMNKSLGNIDFSKSAR
                     EIHNLVRGVNPWPSAYTTYNDVIMKVWKTKVLDEKSTKDVGTIIDVSKDGIKVSTIDN
                     VLLIEEIQMPNKKRMLVGEYIKGNTIETGLVLG"
     gene            15939..16691
                     /locus_tag="ACGI5H_000175"
     CDS             15939..16691
                     /locus_tag="ACGI5H_000175"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890793.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF116 domain-containing protein"
                     /protein_id="HFG9695909.1"
                     /translation="MTDIKKYLTSVGILILILGILIGVVNFFIISLTQIFSLMINIII
                     ISLILIILCSTAVTYRVIKGKYVNSNIMKINFNIVSGLFPIISFIASSFGMSKSDIRR
                     IYIKLNNEYIYSNKYNFNPEDIIILIPHCIQENSCKLKVTNDIDNCKECGRCNIGELI
                     KLKEKTNVKIFVATGGTLARKIIMDNKPKAVVAVACERDLTSGIQDIKKIPVLGVFNK
                     RPNGPCVNTNVDIMDIEKAIGFLTGKNILVCN"
     gene            16760..17461
                     /locus_tag="ACGI5H_000176"
     CDS             16760..17461
                     /locus_tag="ACGI5H_000176"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416253.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc metallopeptidase"
                     /protein_id="HFG9695910.1"
                     /translation="MYPVYGGFWGFDPTMVVLIPAILLTIYAQFKVSSTTNKYLRVNT
                     RRGYTGEQTARRVLDSNGLYDVKIEMVRGHLSDHYDPRRKAVRLSEDVYYGTSITSVA
                     VAAHECGHAIQHAKGYAPLQIRSSLVPVVNFASSISWFLIFLGFIMAGPFLKIGILLF
                     SASVLFQIITLPVEFNASSRAIVQLGNLGIIDESESRQSRRVLSAAALTYVAAALVSI
                     LQLLRLLLIAQRRND"
     gene            17523..18848
                     /gene="rsmB"
                     /locus_tag="ACGI5H_000177"
     CDS             17523..18848
                     /gene="rsmB"
                     /locus_tag="ACGI5H_000177"
                     /EC_number="2.1.1.176"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416255.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0008168 - methyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0001510 - RNA methylation [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (cytosine(967)-C(5))-methyltransferase
                     RsmB"
                     /protein_id="HFG9695911.1"
                     /translation="MDAREVGFKVLCDIEKNDNYSNIAINKHFKNLEISDMDRGLATE
                     LIYGVIENKYYLDYIINKLSKIKVKKMSTYVKIFLRMGTYQILFLDSISDYAAVNETV
                     KLSKKYDKKSSGFINAILRNEIRAKETIMDITEEDSVKYLSIKYSYNSWIIKNWIDKF
                     GQEFAEDLLEANNEKPSIYIRTNTLKISREELIEKLSEMGIVCLKVPMVEEAIKVEKM
                     KNIEKNELFKAGLFTIQDISSMIVGKVINPKEGSFVLDVCSAPGGKSTHLATLMNNTG
                     QVVARDIFEHKLKLINSTVNRLGLKNVFVERFDASEIDENSISKFDYVLADVPCSGFG
                     IIRRKPEIKYKKEEELKDITSIQKKILENASKYVKVGGTLVYSTCTIQDVENINIVTS
                     FVEENHNFEFVPIDTVNVDLDNQDKGYLKIYPNIHGIDGFFIAKLKRIR"
     gene            18856..19887
                     /gene="rlmN"
                     /locus_tag="ACGI5H_000178"
     CDS             18856..19887
                     /gene="rlmN"
                     /locus_tag="ACGI5H_000178"
                     /EC_number="2.1.1.192"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416258.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008757 - S-adenosylmethionine-dependent
                     methyltransferase activity [Evidence IEA];
                     GO_function: GO:0016433 - rRNA (adenine) methyltransferase
                     activity [Evidence IEA];
                     GO_process: GO:0030488 - tRNA methylation [Evidence IEA];
                     GO_process: GO:0070475 - rRNA base methylation [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (adenine(2503)-C(2))-methyltransferase
                     RlmN"
                     /protein_id="HFG9695912.1"
                     /translation="MEKKKIVLKNFTEDELKEFMKTIDEKPFRGSQIFSWIYKGAKTF
                     DDMNNIPKSLRNKLEEVSCIGHIDIELKLESKVDNTKKYLFLLDDGNIIETVMMDYDS
                     RVTVCVSNQVGCRMGCNFCASTMDGLIRNLEPWEILDQVIKIQEDTGKRVSNLVLMGS
                     GEPLDNFENTKQFLKIINEKNGLNIGYRHITLSTCGIVPKMYELADLEIAINLALSLH
                     SPYDEERRKIMPVANAYSIEEILNACRYYIKKTNRRVTFEYSLIKGVNDSEKEAKALA
                     KLLKGMLCHVNLIPINKVEEREYEKPDKAFIYKFRDSLEKNNIPATVRMSMGSDISGA
                     CGQLRRKYK"
     gene            19907..20659
                     /locus_tag="ACGI5H_000179"
     CDS             19907..20659
                     /locus_tag="ACGI5H_000179"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416261.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004722 - protein serine/threonine
                     phosphatase activity [Evidence IEA];
                     GO_process: GO:0006470 - protein dephosphorylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Stp1/IreP family PP2C-type Ser/Thr phosphatase"
                     /protein_id="HFG9695913.1"
                     /translation="MVYSCASHIGKIRKNNEDYCEGEVIDTEHGPIGIFAIADGMGGH
                     KKGEVASKLAVENIIDFLKENLLQHDNVKIDYIDDILKQAYNNVNSIVHKKSMEDIEF
                     EGMGTTLVTAIVYNNVLYVANVGDSRCYLLTDEKFDKITIDHSVVEELMMAHVITEEE
                     ARRHPQRNRITRAIGTDDMVVVDIFKKEIKKSDIILLATDGLTGFIDDEDIRDLILDY
                     EYERTSNISEELISMANDVSGKDNVSVIVIKV"
     gene            20676..22691
                     /gene="prkC"
                     /locus_tag="ACGI5H_000180"
     CDS             20676..22691
                     /gene="prkC"
                     /locus_tag="ACGI5H_000180"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861606.1"
                     /note="PrkC, as found in Clostridium difficile, has a
                     kinase domain, two PASTA domains, and a C-terminal
                     Gly-rich repeat region; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PASTA domain-containing Ser/Thr kinase PrkC"
                     /protein_id="HFG9695914.1"
                     /translation="MGDTILGNRYEIIRKIGDGGMAFVYEAKDRLLNRTVALKVLRPE
                     FVDDDEFLTKFKREAEAVASLSHPNIVNVYDVGEDGKVHYIVMEFVDGKNLKEIIQDE
                     GILDEYTALDITKQIAMALSAAHKKGIIHRDIKPHNILISNEGRVVKVADFGIAKAVS
                     NSTMTNIGSIIGSVHYFSPEQAKGKFVTNNADLYSLGIVLYEMLIGKVPFRGDSPISI
                     ALQHINDDIDFTSEEKVRIPQSVRTTIKKLTEKSSADRYQTAEELIEDIEYIEKNIDL
                     DFIKEYDDFATKKIDEKEINKVVNPTLAKPAPEKVVKPVEVADLDDDEDYYDDFYEED
                     DDEDEEEEEIMRAKKNQRPKSTPSKRTKKKKKKQESPKSRRRLKVIAAVLILILCAQV
                     FLAYKFLFAGGFGNKSLTVPNLVNMTLEEAQSAVEKEGLYLSVKSEEYNSEVDENCII
                     SQTPEGGSTNVKKGDTINVVVSKGSSQASVPNVVGLTLSNAKQLIEENNLKVGTVKYE
                     YSSIYKEGTVLSQSPGAGSSRAQEGDEVNLYVSKGSEKSNTQTPTVPDKKPTTPENNT
                     PTEPGSNSGNSGGNSGGSNSGNSGGNSGNNGSNSGGSNSGNSGGNSGGSNSGDNGGSS
                     GGSNSGDNGGSSGGSNSGDNGDSSGGSNSGDNGGTSSGTGANIGKTE"
     gene            22799..23536
                     /locus_tag="ACGI5H_000181"
     CDS             22799..23536
                     /locus_tag="ACGI5H_000181"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HFG9695915.1"
                     /translation="MKKKTVLITGGARGIGKAMSKAFAKEGYNVLVNFNKSENEAKEL
                     YTILNEKNFSVKLFKADISNREDVEDMVDYCIKEFGGLDVLVNNAGVSQDKLFTDITD
                     EDWDNMMNINLKGSFYCSQVALKYMISEKKGNIINISSIWGISGASCEVHYSITKAGI
                     IGMTKALAKEVGPSNIRVNSIAPGVINTDMLSGYNEEDIDALVEETPLMRLGTPEDIA
                     NCAIFLASDKSNFITGQVISPNGGFVI"
     gene            23634..24518
                     /gene="rsgA"
                     /locus_tag="ACGI5H_000182"
     CDS             23634..24518
                     /gene="rsgA"
                     /locus_tag="ACGI5H_000182"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893669.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003924 - GTPase activity [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_function: GO:0043022 - ribosome binding [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome small subunit-dependent GTPase A"
                     /protein_id="HFG9695916.1"
                     /translation="MLEGKIIKGISGFYYVDTYNGIYECKARGIFRKQKITPLVGDRV
                     KISIVDENEKKGILEEIDSRDTELIRPPIANVDKALIVFAIKNPKPNLSLLDRFIVLA
                     EKENLETVIILTKADLDDNDTLETVKNIYELSGYKVIPVSNITKLNIDKVKEELKENV
                     VVFAGPSGVGKSSLLNEIDENFKLQTGVVSDKIKRGKHTTRHAELLKLEFGGMVADTP
                     GFSSLALEDIEEVELKDYFIEFDKFNDCKFGSKCIHENEPNCAIKEAVTNGEISKERY
                     DSYIQLLHEIRQNNSRRY"
     gene            24523..25194
                     /gene="rpe"
                     /locus_tag="ACGI5H_000183"
     CDS             24523..25194
                     /gene="rpe"
                     /locus_tag="ACGI5H_000183"
                     /EC_number="5.1.3.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003431138.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004750 - D-ribulose-phosphate 3-epimerase
                     activity [Evidence IEA];
                     GO_process: GO:0006098 - pentose-phosphate shunt [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribulose-phosphate 3-epimerase"
                     /protein_id="HFG9695917.1"
                     /translation="MIKLAPSILSADFAKLLEDVRKVESAGCEYLHIDVMDGHFVPNI
                     TLGPLVVKSLKKENINMVFDAHLMIENPDQYIEEFVKAGCDIITVHQEACVHLHRTIQ
                     NIKSHGIKAGVVLNPATPVDTIKHVLPDLDMVLLMSVNPGFGGQSFIPCVLDKIKELK
                     AIIDSQGLNIDIEVDGGISPKNVAEVVQAGANVIVAGSAIFGSDDIQETVNLFRKNAS
                     LEELV"
     gene            25203..25844
                     /locus_tag="ACGI5H_000184"
     CDS             25203..25844
                     /locus_tag="ACGI5H_000184"
                     /EC_number="2.7.6.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416274.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004788 - thiamine diphosphokinase
                     activity [Evidence IEA];
                     GO_process: GO:0006772 - thiamine metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="thiamine diphosphokinase"
                     /protein_id="HFG9695918.1"
                     /translation="MKICIVLNGEIEDYEVTRDIIIKECYDCIICADGGANHTYKMEI
                     MPDYILGDLDSVEEEKINFYKNKGVKFEKFPSKKDETDTELCLFLAKTLKANHIDFFG
                     ALGGRIDHTLANIKLLYYLKEDGIYSRILSDKEEMYIVENEEISLYGNPGDTISVIAI
                     NGDAKGVTLTGLEYPLDNYYMKYSVPIGISNVMLSNSCKIKVEQGCVLVVRNL"
     gene            25975..26604
                     /locus_tag="ACGI5H_000185"
     CDS             25975..26604
                     /locus_tag="ACGI5H_000185"
                     /EC_number="3.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416276.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family hydrolase"
                     /protein_id="HFG9695919.1"
                     /translation="MVDSIIFDLDGTLWDSTEEVCKVWQDVLSEHKEIELSVTKDLFR
                     SLMGLSFEEIANRLFPNLSEEERMNLLNECSLKECDYLSENGAKLFDDIEDTLKLLSK
                     KYKLFIVSNCQAGYIESFLKAHKLEQYFIDFECPGNTGLHKGENNKLIIERNKLINPI
                     YVGDTQGDANSAKFVGIPFIYAKYGFGNVDVYDYFIDSFKDLLEHDILK"
     gene            26659..27315
                     /locus_tag="ACGI5H_000186"
     CDS             26659..27315
                     /locus_tag="ACGI5H_000186"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897777.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nitroreductase family protein"
                     /protein_id="HFG9695920.1"
                     /translation="MELQDTIFKRQSVRKFKNQDVSDEDILKMIKAAGAAPSGKNIQN
                     WHFVVIKRRDLMEKIADVITKKQQEILVEMDKVSVDKANRFRKFVKNFTLFYLKAPVL
                     VLVFTKVYNPSGYYELELIDAPKETIDKLFIRNPGMQSLGAAIENFTLSAIELGYGSC
                     WLTSQNYAADEIEAVLEAETGFEKGEYFLGAMLALGVPEDNLKSPSKKPVEEICTFIK
                     "
     gene            27729..28445
                     /locus_tag="ACGI5H_000187"
     CDS             27729..28445
                     /locus_tag="ACGI5H_000187"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861605.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000156 - phosphorelay response regulator
                     activity [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HFG9695921.1"
                     /translation="MNSYNILVVEDEKEIADAIEIYLLNQGYNVFKGYNGLEGLKVIE
                     NQEIHLAIVDIMMPKMDGITLTMKLRENYNFPVIMLSAKSEEVDKIMGLNIGADDYVT
                     KPFKPLELLARVNSQLRRYTKYLNMVGNKEQKVESDDSVFAIGGLELNENTKEVSIDG
                     KYIKTTPIEFKILSLLMRNAGRVFSADEIYERVWNENAVNTDTVMVHVRNIREKIEID
                     PKNPKYLKVVWGVGYKIEKI"
     gene            28417..30753
                     /locus_tag="ACGI5H_000188"
     CDS             28417..30753
                     /locus_tag="ACGI5H_000188"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012816303.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HFG9695922.1"
                     /translation="MLDTKLKKFKDKYIVTIIVFILMLSASLGMISQYSTIQASAKGG
                     AENPFEQESFVDSIYKGSYVLYHNMKEEQEGKMIQPSKLFINEETMNYIKNVSKEKDT
                     YDGSETYYTDDSINADFNENFENWEHFIKASGKNLKYYLVDKESNFEFFNDNKELGVL
                     DTTKNDASKENSDENQSKNTEMNDEERQKQITDIKENYRFYVVMNFDKDGKVNIVDSY
                     GVNQKIINQMLLSKAREDLMDTSLGGNSISYKLSPIKNITLVYAVPKVISKGDSVEYG
                     YGNTYFDDGIISYISNVENNSYYKISGMILKIILAIVVIVALAFPYRKSKELLGFDTL
                     SRIPLEILFIALAIIQGLVDLYPTVIISNTLSGNYVEYLINNDISAKMASILVSLMNL
                     TYWFVIFSIIFVFIILLKHILNVGIREYFTKHTVTGMFFVWLKKAGKTVINQIRTINL
                     KEKPNKTIVTILGINLLIIVIMCSMWFFGIILALIYSVVLFKILSDYSKKTIYEYNQL
                     LDVTKKISDGNLDVNMEKDLGFFNPIKDELGNIQTGFKKAVDEEVKSQKMKTELISNV
                     SHDLKTPLTSIITYIDLLKDESITDENRKLYIDTLDRKSQRLQHLIEDLFEVSKANSG
                     DVYLNIVNVDIVSLMKQTLLELDDKLADSSLIVKNNFSNEKIILPLDSQRTFRVFENL
                     IINISKYAMPNSRVYIDILETDNKVNIMLKNMSASEIDFSVDDIMERFVRGDKSRNTE
                     GSGLGLAIAKSFIELQGGKMNISVDGDLFKVTITFNKN"
     gene            complement(31070..33748)
                     /gene="mngB"
                     /locus_tag="ACGI5H_000189"
     CDS             complement(31070..33748)
                     /gene="mngB"
                     /locus_tag="ACGI5H_000189"
                     /EC_number="3.2.1.170"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454884.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004559 - alpha-mannosidase activity
                     [Evidence IEA];
                     GO_process: GO:0006013 - mannose metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="mannosylglycerate hydrolase"
                     /protein_id="HFG9695923.1"
                     /translation="MKKTKVHVVPHSHWDREWYFTTSRSKIYLMKDFQDILDILEEKE
                     DFKYFTMDAQASLLDDYLKWRPQDKYRIRDLVQRRRLVIGPWYTQTDQLVISGESIIR
                     NLYYGIDRCNEFGEPMRVGYVPDSFGQSAQMPQIYRGFGIDSSLFWRGVSDDMVDTTE
                     FIWKGSDGSKVLAVQIPFGYYYGGNIPEDDSDLKEYLKDIIVKLKVKASTNNVYFPNG
                     FDQAPIRKNLPDILKKANEIDNENEYEISDIENYIDSVRNERNEFTELKGEFLNAKHM
                     RIHKSIFSSRSDLKIMNNKLENYITNVLEPLLTLSYSLGNEYPHLVIKDIWKLMFENA
                     AHDSIGSCNSDTTNEDVYTRYKQARDLSINLLDLHMRLISTQIKNNNEEITLTVFNGF
                     PEVRNEVVEFDTYIPGQDFVIKNKNGKILNYIIKEKEDITNYILTQTIRLNPSKKIYI
                     PKTVYRAKIALSVKDIPPMGYTQLVFELDTKNKCEIETSNCKEIENKYYKITANKNGS
                     LEILDKESNKTYKNQAVIEDNGDDGDSYNYSPPRKDIYVSSLDSVSSVEVLKSNIQEE
                     MILKYSLTIPASLEERAIGKVSVKMPVTMKITLEPKEQIIKFNVNIKNNQALSHRVRV
                     LFNTEIASKFSIADQQFGIIQRPTVLEKDLALWKRDNYSWQEKPITIEPMQSFVTLED
                     GQRGIALITGCVREYQIVGDNLDTIALTLFRSFGYMGRENLLYRPGRASGEKIIATPD
                     AQLLKELNFDFGLYIYNNKFDEANVANTAKRFLTPIQIYEYADFLNGRLIFAFNDEKQ
                     IYENEFSLMNVNNSNFTVSAIKKEEKGDGIVVRIFNGMKNEDAKGSLNINKNVNDAYS
                     AMLDEIYDNTSKLKVNTKTVEVNSLSHCKVQTIVIK"
     gene            complement(33823..34929)
                     /locus_tag="ACGI5H_000190"
     CDS             complement(33823..34929)
                     /locus_tag="ACGI5H_000190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416284.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS fructose transporter subunit IIC"
                     /protein_id="HFG9695924.1"
                     /translation="MSKKNKSLLSELKGHLMTGISYMLPLVIGSSLVVAIPKLTALAV
                     GITSLDAYKNVSGFYHILYLMEQVGWTGIGLLNTVLAGFIAFSIGEKPAMGAGFIGGL
                     IASNTNAGFLGAVIAGFFAGYVCKFLKKKIKISGSASGMMPLIIMPLITVGLTGFLMS
                     VVLAGPLGNINTSLNAWVAEMCQNGTNSVVLALILGAMIGFDLGGPVNKAAWMAGNAL
                     LLEGIYLPAILVNCAIVIPPLGYGLATFIRKSKFSNALAETGKGNIVMGIIGITEGAI
                     PFTLTNPLKLVPVNMIGCALGVGLSALLGVHAIMPPVGGLYGFISIGSGWAYLVGAIF
                     GALVIAILSTTLVDFNEDETTENTEFDEIELDIM"
     gene            complement(35043..35351)
                     /locus_tag="ACGI5H_000191"
     CDS             complement(35043..35351)
                     /locus_tag="ACGI5H_000191"
                     /EC_number="2.7.1.202"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454881.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016301 - kinase activity [Evidence IEA];
                     GO_function: GO:0022877 -
                     protein-N(PI)-phosphohistidine-fructose phosphotransferase
                     system transporter activity [Evidence IEA];
                     GO_function: GO:0090563 - protein-phosphocysteine-sugar
                     phosphotransferase activity [Evidence IEA];
                     GO_function: GO:0090582 -
                     protein-phosphocysteine-D-fructose-phosphotransferase
                     system transporter activity [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA];
                     GO_process: GO:0016310 - phosphorylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS fructose transporter subunit IIB"
                     /protein_id="HFG9695925.1"
                     /translation="MKIVAITSCIAGLAHTPMAAKALEQAASKMGHEIKVEQQGAMGR
                     VNTITKEEAQDADFILIASDQTISGMERFDGKKVIKVKIGIALKKPEAVLTKCIEAIS
                     "
     gene            complement(35354..35806)
                     /locus_tag="ACGI5H_000192"
     CDS             complement(35354..35806)
                     /locus_tag="ACGI5H_000192"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729391.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:1902495 - transmembrane transporter
                     complex [Evidence IEA];
                     GO_function: GO:0016301 - kinase activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA];
                     GO_process: GO:0016310 - phosphorylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HFG9695926.1"
                     /translation="MVLQEKYIFIDKDLKSKEEVLNFIADSAYILGITTNKEALLKDL
                     LKRENEFPTGIKDGFAIPHTKSVNVKEASILYIKTTNELEWKTLDDSKVRYVFSLLAP
                     HKNEGNIHLKTLSKLATCLMEDDFTSEVKNASDASHLVKYITNKMKEE"
     gene            36040..37968
                     /locus_tag="ACGI5H_000193"
     CDS             36040..37968
                     /locus_tag="ACGI5H_000193"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454876.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antiterminator"
                     /protein_id="HFG9695927.1"
                     /translation="MHKRLLTLFKLLNESDDKITCKTLSNHLKVSERTIRNDITSING
                     TLEKNGAIIKIKKGEGYYIDILNLALYQQYLALISDDIMDSSEIPDSPIERNQYILKY
                     ILYNNTYIKLEDLANSLYVSKFTILNDIKRIKPILSKYNLILVSKPYYGVKVEGKEID
                     IRRCISNNMINRNFENYIIGITDREIELFNNVDLIELQRVVLSEINKFNINFLDFNLK
                     NFIIHLAITVSRILDGYCLDNVLDVVLTDFQSNTTVENIFNYIESKYTIIISKADRVY
                     LYNHFITKSSLLDNVSNRVDTKIIEYVEEILEVINNQYTFDLRNDSVLFDDLVLHFKS
                     ILNSKSYNLNKVNPLINTIKSNYPLAFEITLNAIEKVFKNSIYSLTEDEIGYVSLHIG
                     AGIERFFQSNIKCKNVVLVCGSGYGSSRLLEVQLNKVFHDKINILQCLSFNQFLASEL
                     SDVDIIISTIPLNHDSIPIVLVDLKLLKKDIENISKSITNNSHIYSNLLDNFFDKNLF
                     IVNPKIKDKDELIKLMCNKLTQSEIVFPSFAESVFYRESLSSTNIDDFLAIPHPMELS
                     SIRTKICISILNEPIYWSENSTVKLIMMLAINKDDYIKINSIYDILLKIIHDNDIRDS
                     ISNCNDFDNFLSIIKSIV"
     gene            complement(38228..38989)
                     /locus_tag="ACGI5H_000194"
     CDS             complement(38228..38989)
                     /locus_tag="ACGI5H_000194"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454874.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HFG9695928.1"
                     /translation="MEYTVQKLSKLAGISTRTLRYYDEIGLLKPLKINSSGYRIYGQN
                     EVNKLQQILFYRELGINLENIKNIINSPNFDSLSALKEHHNKLLAKRKQIDLLIENVT
                     KTIALKEGKYTMTDIEKFEGFKEKMIDENEKNYGTEIREKYGKDIIDTSNKKLKNMSK
                     QDYENWQNLNIEIISKLKKAFKTGDASSELAQEVAKLHHKWLCYTWNTYSKEAHSSLA
                     QMYVYDERFTSYYDREQPGLAKFLRDAIVIYTRDK"
     gene            39208..39684
                     /locus_tag="ACGI5H_000195"
     CDS             39208..39684
                     /locus_tag="ACGI5H_000195"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454873.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Rpn family recombination-promoting
                     nuclease/putative transposase"
                     /protein_id="HFG9695929.1"
                     /translation="MNLKRSNEKREEYRRMYSDKESFLSLIQNFTSVSIAKELTLKNI
                     ELETSFICEYKGKEVDIIYKVFSKSGKVSHYIVLEFQTEMDTEIVPRLKSYREQIWKS
                     FIMKKSLEEIEDKNFKLPKVIPVVLYSGPERLSRKKGILDIVESISEFSNNSSMKN"
     gene            39782..39934
                     /locus_tag="ACGI5H_000196"
     CDS             39782..39934
                     /locus_tag="ACGI5H_000196"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893656.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-oxoglutarate translocator"
                     /protein_id="HFG9695930.1"
                     /translation="MRNNKSKVLLGILCLATGMAVILSMLLPGWIWSALTALILIGCG
                     ALLFFC"
     gene            complement(40094..40282)
                     /gene="rpmB"
                     /locus_tag="ACGI5H_000197"
     CDS             complement(40094..40282)
                     /gene="rpmB"
                     /locus_tag="ACGI5H_000197"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L28"
                     /protein_id="HFG9695931.1"
                     /translation="MAKVCSVCGKGKVSGNQVSHSNKHNKRTWSANLRSVRAIIDGAP
                     KRVKVCTRCLRSGKIERA"
     gene            40643..40993
                     /locus_tag="ACGI5H_000198"
     CDS             40643..40993
                     /locus_tag="ACGI5H_000198"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003431114.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp23/Gls24 family envelope stress response
                     protein"
                     /protein_id="HFG9695932.1"
                     /translation="MSAKVTNQYGNIEIDNQVIAQVVYRAAMESYGLVGLAYKSKGIV
                     ELLKGENATKGVRVEEVEEDAIAIELYVIIQYGTNISTVANNIIDRVKYVVEKMTGVR
                     VTRIDINVQGIRVK"
     gene            41012..42655
                     /locus_tag="ACGI5H_000199"
     CDS             41012..42655
                     /locus_tag="ACGI5H_000199"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DAK2 domain-containing protein"
                     /protein_id="HFG9695933.1"
                     /translation="MIQYIDGKRLREMFISGANNLQNNKELVDKLNVFPVPDGDTGTN
                     MSLTISYALKELAKVENDNISDIGKALSKGSLMGARGNSGVILSQIIRGIAKSIEGKS
                     KLSTEDLAKAFKNGSDTAYKAVIKPIEGTILTVVRESGEFAIKTAKKEKDVVKFLSML
                     VKESNSSLERTPDLLKNLKEAGVVDSGGKGLVLIYEGMLASIKGDNIEIKNVDLDTNI
                     STSMDFAKSTTSTDDIKYCYCTEFILESSKVEDTKIRDIMMAYGDSLAVVGDDGVIKV
                     HVHTNDPGNVLQEALKYGQLLTIKIENMKLQHENTLLDVEEKKENDSEPLEEEKEFGF
                     IATSMGEGLANIFKDFGVDHIIEGGQTMNPSTEDFMNAIKHINAKNIFIFPNNSNIIM
                     AANQAKELSDKNIIVIPTKNTPQGFAALVTFNGELSEDENKEAMMNALNSVKSGQVTF
                     AVRDTVMNEIDVKEGNIIGIAEGNLLSAGDYVDEVTSNLIEKLVDEDTAIITLFFGED
                     VTESQANELRTSLEEKFEDVDVELYYGGQPLYYYLISVE"
     gene            42736..44793
                     /gene="recG"
                     /locus_tag="ACGI5H_000200"
     CDS             42736..44793
                     /gene="recG"
                     /locus_tag="ACGI5H_000200"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416309.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003676 - nucleic acid binding [Evidence
                     IEA];
                     GO_function: GO:0003678 - DNA helicase activity [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent DNA helicase RecG"
                     /protein_id="HFG9695934.1"
                     /translation="MDLYKDVQYVKGIGPKKADKLNKLGIFTLKDLLYYFPRQFEDRN
                     NLKKIAQLEDGEKVTIKAVISSINTFSPKEGMTLTKIDVKDETGSAKLVFFNKSYIKN
                     TFRPGDSILVFGKVKKKFNNLELTSCELEYLTNSPKNTCRFMPVYQLTYGVTNKEIMS
                     IIRTVLEDKELIIQEYMPQRIIEKYRLCSIDFAVRNIHSPSSKESLKIALYRIVFEEL
                     LILQLGLFVFKSGRNKEDGIKFETSKDLKKIISALPFKLTKAQNRALDEIIQDMNLEK
                     IMNRLVQGDVGSGKTVVALLALANCVLNGYQGALMAPTEILAGQHYISLTESLKDFGI
                     NVGLLIGSLTKKQKDTVLEQIKNNEIDILIGTHALIEDKVEFNNIGLVITDEQHRFGV
                     MQRSKLSLKGANPDILVMTATPIPRTLALILYGDLDISIIDELPPGRQPIETIAIEKS
                     KRDRAYNNLVRREVESGRQVYIVCPLVEESEAIEAKSAVELVEELRAEYFHDLRLGLL
                     HGKMKSSEKDEVMRLFKDKEIDILVSTTVIEVGVNVPNATLMIIENAERFGLAQLHQL
                     RGRVGRGSHKSYCVLIYDSKTDVCRQRMAIMEETNDGFKISEKDLEIRGPGEFFGTRQ
                     HGLPELKVANLFKHIKILKLAQQEARYILGEDNNLQLKENMALKKEIIDKFKDTLKEI
                     SLN"
     gene            44852..45406
                     /gene="rsmD"
                     /locus_tag="ACGI5H_000201"
     CDS             44852..45406
                     /gene="rsmD"
                     /locus_tag="ACGI5H_000201"
                     /EC_number="2.1.1.171"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003431108.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0052913 - 16S rRNA
                     (guanine(966)-N(2))-methyltransferase activity [Evidence
                     IEA];
                     GO_process: GO:0031167 - rRNA methylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (guanine(966)-N(2))-methyltransferase
                     RsmD"
                     /protein_id="HFG9695935.1"
                     /translation="MRVISGKARGLKLNTPKNEDVRPTTDRVKESLFNMINSYIMESE
                     VLDLFAGTGSLGIECLSRGAKSCTFVDISKESIDIVKSNIKKARVESESIILNLDFKT
                     AIDKLKLQNSKFDIIFMDPPYYKNMFIEAIEKIDNSNLLNEDGIIVVEHDTNDLFPDK
                     ICKLEKTRDKKYGNTTLTFYKMEA"
     gene            45408..45905
                     /gene="coaD"
                     /locus_tag="ACGI5H_000202"
     CDS             45408..45905
                     /gene="coaD"
                     /locus_tag="ACGI5H_000202"
                     /EC_number="2.7.7.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416314.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004595 - pantetheine-phosphate
                     adenylyltransferase activity [Evidence IEA];
                     GO_process: GO:0015937 - coenzyme A biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pantetheine-phosphate adenylyltransferase"
                     /protein_id="HFG9695936.1"
                     /translation="MENKPRKAIFAGSFDPITNGHLDIICRASKLFDELQIGVLNNPN
                     KKGLFSFDERVKLIEKSTSHLNNIKVVTFDGLLINYCQENGIGALVRGVRSGADVDYE
                     LQMAHMNRELNPDIETIILPSCTKYSFISSSLIKEVLLFDADIKNLVPKIVLEELKKK
                     TSGGN"
     gene            45909..46433
                     /locus_tag="ACGI5H_000203"
     CDS             45909..46433
                     /locus_tag="ACGI5H_000203"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454870.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9695937.1"
                     /translation="MKIDLEMIELFEQLEEIFRSASTIPFSHKCTVDKDEVLAIINDI
                     RTLIPEEVTQAVWINKERNKIISQAKQDATNIVEQAKKEAERIQQEYQDNIEELKKNS
                     EDVVKAYVESSEPVVQADQRAKDIVDRAERIANEIRIGSIEYAEDVLSSVEYNLREIL
                     EEVKRDKAELRPKK"
     gene            46777..48696
                     /locus_tag="ACGI5H_000204"
     CDS             46777..48696
                     /locus_tag="ACGI5H_000204"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897758.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antiterminator"
                     /protein_id="HFG9695938.1"
                     /translation="MKERAKKILDFIIKNNNVTSQELQEKFNVSKRTIYYDILAINEQ
                     LGKSGNIKNVKHKFIFEGNLCDARKIISTEEDKFLDSDYRKTFILNKILLGEKISIEK
                     LTNEMLLSKNTVVQTITDVKKYLQTMGLRLEYKGKYKIIGDEYVIRELFLIIVQENIL
                     EINSISEEVSSFDTKGHIKLTDYSLLNLTKFVEFLNKRIRDGKTLYSYKYLNEAKKIS
                     YFSNCKELLCEEANENEQAYICTYISSLPSLNSEVKEDVVEEYVDKLIDKFEVNTAIK
                     LESKHEFKKNILRHLHSSYNRIRFKFPIRNPMLDETKYKHESLYKIIKSIIENEEEFP
                     VFEGIREEEIGFIAAYFGGYLRGSRDNGLRRNKVLLVCPNGLMVSKSLEIQLYKYIPT
                     IEIVGIVSIKQLKEVNVYYDYIITTIDIQNVNNVIVVNPLLTSSDVQLLMNKLISVKE
                     NEKYFNLELIIQAIRKNGVINNEEALKADLLNIIHKIDEGEMYQPMLKELINAERVNI
                     IKSVRDWKEAIKIASKPLLEDNSIEELYIENMIKSVEKYGPYIVLADRFALPHASSKE
                     GVNKLAMSLLIVEDEVDLLGKPVNIFMVLAAVDNTTHIRALASLSEMMYEEENVKLII
                     NGDKSSILELINKQN"
     gene            48709..48996
                     /locus_tag="ACGI5H_000205"
     CDS             48709..48996
                     /locus_tag="ACGI5H_000205"
                     /EC_number="2.7.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003431103.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HFG9695939.1"
                     /translation="MKILAVCGFGVGSSMVLKMTIQKALKQLGIECEVENTDINSARG
                     ADCDCIFTSQELLNELKGTCNVDVYPVKKYMDLAEVTEVVQTFLSDKNDKK"
     gene            49129..50388
                     /locus_tag="ACGI5H_000206"
     CDS             49129..50388
                     /locus_tag="ACGI5H_000206"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890757.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS ascorbate transporter subunit IIC"
                     /protein_id="HFG9695940.1"
                     /translation="MLDFISNNILRNPSMLIGLIAAFGLVLQKKKASDVIKGSLLAAF
                     GIIIMETGTGMLVSSIAPINGAFQSISGGAVTKGLSDVTFTASYGGIIGLAMFAGLAI
                     HLMIARFTPIKTIFLTGHMLYWFPFIFVASGVEAGLNGGVLIAFAAVLSALYWSIMPW
                     LLRKYVFDVIGDDSFTLGHPSGCLALISGFVAKLVGNKEKSTEDINIPQSLSFFREIS
                     ISGGMAVFLMFIVVGIVIPGAFKDSNEFIGTYAIKQGLSFGAGLIIMLHGVRMLINQI
                     MPAFQGISEKVVPNALPAFDCPILFNYKPNAVLMGFLVAMLTSTAMILICNYFNVFNL
                     LLIPLVITSFFECGAAAVIGESQGGIRGAIIGTAIAAIFMVVLVGISAVIYSGTIQNW
                     ILIFGGNDLSLFGIISRFIGSLFGGIL"
     gene            50391..51131
                     /locus_tag="ACGI5H_000207"
     CDS             50391..51131
                     /locus_tag="ACGI5H_000207"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454865.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SIS domain-containing protein"
                     /protein_id="HFG9695941.1"
                     /translation="MKFKYIDEIRRLIDIIENEEKVNMEKAVQIFVEAIESKNAIFSF
                     GASHAGILTEELFYRAGGCVLINPVFAKSLMLDTAPITHTSKMERLEGYGTALADKTP
                     IKKGDVVIVHSVSGRNPVSIEFAMKAKENKAIVICITNLSYSKSVSSRHSSGKKLYEV
                     CDLVIDNHGQKGDACVEIDGLNQKVSPTSTVIATTVMNSIIAQATQELVNKGLKNPPI
                     FYSANIDGGDELNKKIFDEYKSVIHYEY"
     gene            51454..52764
                     /locus_tag="ACGI5H_000208"
     CDS             51454..52764
                     /locus_tag="ACGI5H_000208"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729386.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter substrate-binding protein"
                     /protein_id="HFG9695942.1"
                     /translation="MKKENKMEGIKVGMLKKLCSLAMVAIMTTTLITGCSSGNGKDSK
                     KDGEKEKLVLWMPPVENNMKEVWDPILDKFEEKNNCEVDLQIIPWDNYSEKFATAISA
                     GEGPDVGYMYAEMYPQFIESGAVEDLTNYATKEDKEQSIYIKTSEMMGGMYGMPFQAA
                     NPGVLYYNKDILEKLGEKPPKTWEDFKRICKKATQDTDGDGKIDQWGLAQGWGAKTFG
                     NLNWNWYPYLWQAGGDIFNDDLKSVKFNDKSGLEAAKFLKELQAYVPEDSLSKDSNEM
                     IESVFGPGKAAFTIMLSSAATSVFDESFPDLNWGFVTGLEDKKAATFGAVDHLSLISS
                     AKNKELAYKLIQHMLSVESMTEFHKAIPRAPITKGEPYQGDERFKEMVENDKNVYRPL
                     VVGPHGVEIYEYLWKELQTMISGDKTPKQALDDAAKYSNDLLAQ"
     gene            52862..53779
                     /locus_tag="ACGI5H_000209"
     CDS             52862..53779
                     /locus_tag="ACGI5H_000209"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416320.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HFG9695943.1"
                     /translation="MENLVREFEENSKRKKTKLNIKPYMYILPLGIILVAFYVIPIIM
                     SIYFSFTKYNIISPATFIGLENYKKLFTDETLKVSIINTIKFTVVVVPCQTILSLILA
                     VWITGKGNSKIASFAKGAIFIPVLSSMVLIGMVWRALLNGEGSIIYQVLGAFGIESSK
                     LLGDSKTALPTLMFISMWKNIGYFMVIYISAIMNLPKHCYEVAKVDGATKLQEFIKIT
                     VPLLKPTTIMVVFLGSIWSLQVFDLIYTVTGGGPGISTMSIVMHAFNLNFKNFNSGYA
                     MTVANVLFLLIAVVSILQNKLVKRDNSDF"
     gene            53795..54604
                     /locus_tag="ACGI5H_000210"
     CDS             53795..54604
                     /locus_tag="ACGI5H_000210"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416323.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HFG9695944.1"
                     /translation="MKTARRLLSDGLLLFIACASLVPFIYMLIISLKITYNSYSLDIS
                     FSTVTLQNYIDIFTKKGFAQYFFNTAIVSFSGVLLNLVFSTLAGYSFAKMDFKGSDKL
                     FLFMIMTLIIPSQVTMIPLYIIMKHLGWINSYLALIMPIPTAFGVFIMRQAILGVPKE
                     LLESAKIDGCSDFRILIQIVLPLIKPALITLAIFTFMGAWNEFMWPLIATTKDAMRTL
                     TVGLSTLKTFQITNYGQMMAGATITFLPPFIFYLILQSKFVEGVSLSGIKG"
     gene            54662..56410
                     /locus_tag="ACGI5H_000211"
     CDS             54662..56410
                     /locus_tag="ACGI5H_000211"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454861.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4091 domain-containing protein"
                     /protein_id="HFG9695945.1"
                     /translation="MEISYVLKDCTFKHNKYSVVEAETWKDKDLDIVVAKGEKFAFQI
                     MLKATEEFNCTIDKSSAISWKGLGNRVRLALNMPNSLENNFSINILGYVQDDTKAFVN
                     DAILRDKDVLVEQYLPQTFWIEGQVPEDFEENNLDIGIDIFKSFGYEDEEKVCTIDVP
                     VKVRNVVLKPLDESKFFLDLWQHPSCLARMYKVELWSDIHFEIVDNYLKELASLGEKV
                     ATVIVSDYPWAGQSCYKVYKNPSNLYEYNMVSVSKGLDGKIKCNFESMDRYIGIADKY
                     KMAKEIDLFGLLGNWCAGEFGNPVEGYKDPIRVRYFDEKDKVFKFINNTNDLKEYIGL
                     VLNHLIECGLWDRVRIIADEPNNPEVVKECIEFINSTVGTHQVKYKSATHDQNFLDRA
                     KDEIDDMSINLKLTIQNYKDIESLKKKINDKGGILTWFVCCFPEKPNSFLSSPFVENR
                     IIGWYTYYFGLDGFLRWDYNLWTEDPWKDSSYKFPIWKAGDMFFVYPGKDLKPVRSVR
                     MENLRFGIQDFELFTMLEKEKVREYIEVELMQELLNKKENAEIKGFGDIELGYSLDNW
                     RYDKVKKYVLELLDRV"
     gene            56714..57694
                     /locus_tag="ACGI5H_000212"
     CDS             56714..57694
                     /locus_tag="ACGI5H_000212"
                     /EC_number="3.2.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416329.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004553 - hydrolase activity, hydrolyzing
                     O-glycosyl compounds [Evidence IEA];
                     GO_process: GO:0071704 - obsolete organic substance
                     metabolic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 5 protein"
                     /protein_id="HFG9695946.1"
                     /translation="MFFLSISFIGFYLVIRDNSDTVKMQRGINIGNALESPKDFPWDV
                     KMSNKFFDDIKDAGFDTVRIPVRFSDYTSDSDNFKIDEEFFKKIDKYVDYALDKDLIV
                     VLDLHHFEEIMKEPRVHKEKFLKIWQQIANRYQKYDKKLVFELLNEPKENLSSQLLNE
                     YIEEAIKIIRKTNPKRTIIVGPYNFYQIDYLNELNIPKDSNIVVSFHYYEPNDFAFQG
                     NIYHKGFEHLSNITWEGTNEQMDYLKKRFDTVENWANKNKVKIFLGEFGITKEAPEVS
                     RRAWIKAVREEAEKRNFSWAYWELASGFGIYNQIEGTWDRDILSALIEKR"
     gene            57699..60005
                     /locus_tag="ACGI5H_000213"
     CDS             57699..60005
                     /locus_tag="ACGI5H_000213"
                     /EC_number="2.4.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HFG9695947.1"
                     /translation="MKKNSKKILITLTIITNVIYILWRIFYTVPKEEGKFALICAIIL
                     LFVEIMGMMEMFVHYYGMSNIEYPEKPIISEELYPHVDVFIATYNESVDLVRKTVNGC
                     IHMQYPDKKKVHIYICDDGNREEMRILAEKMGVNYITRTEREGAKAGNLNNAMQHTTS
                     PLIATFDADMIPMHDFLIATVPYFLKNEQAKKDGEKEEYEKVGFVQTPQSFYNPDLFQ
                     FNLHSEGRIPNEQDYFYRDIQLARNRTNSVIYGGSNTVISREALEEVDGFYTYSITED
                     FATGILIQSKGYRCYAIPEVHASGLSPTDLKSLIKQRERWARGCIQTGRRLNILFRRG
                     LGFWQKISYISSITYWYASIKRFVYIMAPILFSVFNVIVVKCTLLQVLVFWLPMYILS
                     SLSLKIFSQNIRNTRWTNIYETIMFQSLMPAVILETFAISKNKFSVTNKSKLEENRMY
                     KFLQGIPYFIYMVLSIIGILKMFVAIFKMSSMTYSVVLFWLIGNLFNLVMATLFISGR
                     QQLRKSERYIAEIDFKLKQNSYVLSSKTIDISENGFAFLLENPEYISPEEEFEVEFRE
                     KSGNEMYIANMKAKIVNVVEVNSKWKYAAYITHIEDSEIDNWMCIVHDRIPTLPMTIS
                     NQLGFFDDLQINVKKRIEKTRTLSRRSPRINMNFQMDIKNTGKLRIVNFNYQYVLLNF
                     ENKSIYPKEIALEINENIVLECDLCEGKIDERGILYKVNNIDSIMQNFFLRDEMMDWI
                     LQNKTILVSKPSEKKEKSIDEFEPMEYI"
     gene            60016..61092
                     /locus_tag="ACGI5H_000214"
     CDS             60016..61092
                     /locus_tag="ACGI5H_000214"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861593.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9695948.1"
                     /translation="MKTLKVFFCSTKYLILVFIFFINTTFISSATSDKILDLSFKKIE
                     TDLNSKITYEDTGVKIETDSSKSDKERYLYIYQNIKENWSMYNNFYIEIQNKNKSSQR
                     INLSIQSKNMLEFRLKEGSEVFLEGKNIIYSDKIKEGCIEVPGEFEGKIYVNFNSLIN
                     EESNVVLDSNMLSNIVSWGITFIPSDEEHNIVIIKKISLLSEEKLRFLNNIKIIGDEE
                     VQIPVLGQSISQYEVLGLKSDSKIKYSLMGKQDNVSISQKGKLTLSNKAKPGQIILQV
                     NVDDKFKIGKKITLTESWSVNKKDKDGVPYTLVYPEQSPTVQDMKKINFMNNIITFVR
                     ILFVSLVIICFGIYLYWKKCSKTK"
     gene            61110..62528
                     /locus_tag="ACGI5H_000215"
     CDS             61110..62528
                     /locus_tag="ACGI5H_000215"
                     /EC_number="2.3.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416335.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016746 - acyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MBOAT family O-acyltransferase"
                     /protein_id="HFG9695949.1"
                     /translation="MLFSSLIFLFYFLPITLVLYYVFRFNRTIQNMILLAVSLFFYAW
                     GEPKFVVIMIVSIIMNYIFGLLVDRYRESKIKVKVFLVLMCAYNIGVLFIFKYLAFAL
                     RNISELISTELTIPSIVLPIGISFFTFQGMSYVIDVYRRHGEVQKNPFYVGLYIAFFP
                     QLIAGPIVRYESVAEQILNRKETWNKFSIGTCRFITGLGKKVLISNNMAIVADYIYTM
                     NSQGEIAASLAWLGSIAYTLQIFFDFSAYSDMAIGLGLMFGFKFEENFNYPYISKSIS
                     EFWRRWHISLGMWFKSYIYFPLGGSRVANKDIMIRNMFIVWLFTGIWHGAEWTFVIWG
                     ILNFVFLIIERFIMFEKIENHNFIKHIYALLVVNFGWVLFRSPNLKEAYNYFKAMFGG
                     NGAIWSDYTYMFLKEYWVFFIFAFIFSVPIAKKINKFVVEQAKYSMIFNVFYPISAIL
                     LFFISVTYLVTGSYNPFIYFNF"
     gene            62543..63751
                     /locus_tag="ACGI5H_000216"
     CDS             62543..63751
                     /locus_tag="ACGI5H_000216"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003431084.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9695950.1"
                     /translation="MNRFFKVRLITAIMFLIILFAFSIFNVCYSGKDTIQEIKNSIAE
                     KSSLKDTISSIDNTVNDKVIYKNTFIETYGYLQKLMGKNEFSKFSVVKDTSGKMHYTY
                     FAKAPNPVGVIADRVRKFSDEMEKQNTKLVYLMTPDKYIKGVTKFPKGIPYSYSNETA
                     DNFLNQLKKYNVDYIDFRENILKSGIPKDDLFFKTDHHWKVETSFWAFGELVEQLNKK
                     YNMNLDENHYYRDKDNYNSIVYPKSFLGSMGRKTGILYGGIDDFTLIYPKFKTNYTYY
                     TDSKSQKFELKGRFEESLILSYPFNADLDLMDGQSDKYFTYLLGNRPLVKIKNIENPD
                     GLKVLFVKDSLIVPTAAFFSSVCSSIDMIDPRYYDGDILEYAKSHDYDFVFISVYPQN
                     LTKEFFPFCE"
     gene            complement(63825..65213)
                     /locus_tag="ACGI5H_000217"
     CDS             complement(63825..65213)
                     /locus_tag="ACGI5H_000217"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861591.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0015293 - symporter activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cation:dicarboxylase symporter family
                     transporter"
                     /protein_id="HFG9695951.1"
                     /translation="MESSFLSQFLMITDFKTIFFIILLLGTFFIVRQFEKKKIKFSLR
                     TIYATVLGLILGIIIQAFAGFPNDTTQVIWLQEVSKWYSLFGSGFMDLLKMLVVPLVF
                     LSIIKVIINMKDNNLGTLTFKSLGMLLATTAIAAIVGIIVANIMKLGVGANMPTLVEN
                     QELKEINSLVDTLRGLLPSNPVMAMANGNIVATIIFATFIATSIKRLSKKHFETIKPF
                     IGFIEASYKIIVSVSMTVIKFMPYAVVALLANTITSQGISSIVSVLQFILALYISVAI
                     LFIIHLIFITLNGLNPITYIKNSTEALLLAFTSRSSLGTLPVTIESLVQNHGVDEGVS
                     SFTASLGANMGMNGCAGIYPALMAVTLANMAGVNMDMSFYVMLLIVITISSFGIAGLP
                     GTATMAVSVVISGVGLGSYFPLVGGILAIDPILDMGRTMINVNGAMVSSITVGKSLGK
                     IDKEVFSKKNIS"
     gene            65554..66888
                     /locus_tag="ACGI5H_000218"
     CDS             65554..66888
                     /locus_tag="ACGI5H_000218"
                     /EC_number="1.8.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893646.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA];
                     GO_process: GO:0045454 - cell redox homeostasis [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="CoA-disulfide reductase"
                     /protein_id="HFG9695952.1"
                     /translation="MRVIIIGGVAAGMSAAAKLKRIKPEYEVVVYEKTEIVSFGACGL
                     PYFVGGFFNDADELLARTPEKLREAGIDLNIFREVVEVDSESKKIKVKNIKTDEIYED
                     YYDKLMIATGARSIMPPIKNIKLKNVSTLKSLYDGEYLKKLLSNEDNKRVTIIGAGFI
                     GLEAVEACKKLGKDVDVIQLEDRILPQVFDKEMTDVLEEEINRHNVNLHLDEMVVELC
                     GEDKVEKVITNKGEIDTDVVIIATGVRPNTEFLSNTNIKMLKNGAIVVDEYGRTSVED
                     IYSAGDCATIKNIVSNENVYVPLATGANKLGRIVGENLAGREISYQGSLSSSCIKIMD
                     MEAASTGITERQAKDLGINVKSKFISDYNQTHYYPGRNKIYVKLIYDADTKVILGGQV
                     AGFKDAVQRANVLAAAIFGKMTTNQLGMLDLCYAPPFARTWDVLNVAGNVSK"
     gene            complement(67030..67947)
                     /locus_tag="ACGI5H_000219"
     CDS             complement(67030..67947)
                     /locus_tag="ACGI5H_000219"
                     /EC_number="3.1.26.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003431079.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016891 - RNA endonuclease activity,
                     producing 5'-phosphomonoesters [Evidence IEA];
                     GO_process: GO:0042780 - tRNA 3'-end processing [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease Z"
                     /protein_id="HFG9695953.1"
                     /translation="MIDLTLLGCGGNVPMPNRFLSSVFINYKGRKILIDCGEGTQVSM
                     KLKKCGFKDIDLICITHLHGDHIFGLLGLLSTIGNSGRTSDLTIVGPVGIVDCIRSMR
                     NLVEYVPYTLKIIENPQGNFSLDNKVLRNLEISTISLEHSIECLGYSFNFRRNPKFDI
                     DKATKNEVPKILWNKLQEGQNIVLDSKQYTPDMVLGELRKGVKISLTTDTRPIESIPD
                     FIKDSDLFICEAMYGDDLDISKAVRNKHMTFREAANLAKLGNVKQLLLTHFSPSLDIP
                     SMYLENATNVFENTILGEDRLSLRLNFDE"
     gene            68155..69039
                     /locus_tag="ACGI5H_000220"
     CDS             68155..69039
                     /locus_tag="ACGI5H_000220"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003431076.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4846 domain-containing protein"
                     /protein_id="HFG9695954.1"
                     /translation="MKVLKKITILSLITLTLVGCSNGEEKKVVEGSKKTQNSKKDEQP
                     IIVHKDANILKDRYEPPKGFKRVDVEKGSFESFLRNTKLKNYGEKVKYYDGRTKESKG
                     IYDSVFDVDIGNRDLHQCADAIMLMRAEYLYQNKLYDEISFDFVDGFKAKYSKWAQGY
                     RISVKDSGSSWYKATEYSTSYESFRKFMDIVFAYSGTLSLEKELEPVKVEDMKIGDVF
                     IVGGSPGHASIIMDMAENEKTGEKVFMIAQSYMPAQQTQLLINRKNPNLSPWYSLDFE
                     GDLTIPQWTFKRDQLKRF"
     gene            69252..71093
                     /locus_tag="ACGI5H_000221"
     CDS             69252..71093
                     /locus_tag="ACGI5H_000221"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729380.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional metallophosphatase/5'-nucleotidase"
                     /protein_id="HFG9695955.1"
                     /translation="MKIRRYLILVIIILITTSQSFISYGLERFEEITIFHTNDIHGRY
                     AEGDDHIQIGNLATLKKETPNSILVDAGDCLHGLPIVNMDRGKSAIELIKCAGYDYIT
                     PGNHDFNYGKDRLFELSKSANLGENTLKFLSSNIFENGKKVFDSNDIKEIDGIKIGFF
                     GLSTQETKSKTGFKNVEGLEFKNPIESATEQVNELKGKGANVIVAICHIGTNSLSKPN
                     SIDIANEVQGIDLIIDGHSHTKFENGKQVGDTLIVSAGQYLENIGEIKLTLDTNDVED
                     IKIENKSARLIGKEEALKYKLDSVVSKKVDKIKEQQEKILDKVIGVTTNTLDGSYENV
                     RTKETNLGNLISDILLDKTKADISLFNGGNIRDTIEKGNITRRDIVDVFPFSNTIVTK
                     ELTGAQIKDVLEHGVKLYPEKSSAFLQVGGISYYFNPKQKEGEKITNIQKEGKPLDLN
                     KKYVVATNDYIASGGDEFPCFSKEPVLKEFGNLESAVIEYIEYKKEISKNVDGRIGIK
                     SKDELISKNHESDLILSENEKNINDNEENLSNNIKSSDSDKNKSLDKTSSRESSNLGI
                     SKREAKEKSPKTGDLGFSNSIIIFIVSSTLICLLNFNQKELKDKKSK"
     gene            71398..72105
                     /locus_tag="ACGI5H_000222"
     CDS             71398..72105
                     /locus_tag="ACGI5H_000222"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861589.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000156 - phosphorelay response regulator
                     activity [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HFG9695956.1"
                     /translation="MNNILLLEDDKSLNRGISFKLKKEGYNVFSAFGIEEAKNIFAKE
                     EICLIISDIGLPDGSGFDFCEEIRKKSDVYIIMLTALDEEVDIVTGYDLGADDYITKP
                     FSLMVLISKVNALMKRVNTVKNYTLLVCDDLFFYYIENKLIIRTDDKEEEIILSKTET
                     KLLKYLMENSMQTLTKEQLLESLWDSSGNFVDDNTIAVNIRRLRQKVEKNPSEPKYIK
                     TVRGVGYMWGERSIKKC"
     gene            72099..73409
                     /locus_tag="ACGI5H_000223"
     CDS             72099..73409
                     /locus_tag="ACGI5H_000223"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003431070.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing sensor histidine kinase"
                     /protein_id="HFG9695957.1"
                     /translation="MLKNMNLKDGLSVKDDYIMRRVIVYSVLSVLIVTLVFILFEYSR
                     LHKLYEHQIKNTQNVAGILIEKYPNDEIDIVNSIYNSDYSKVSTGEKAFKKFGYGLEN
                     KMSNDKNFSLYLKSFFKESFFIFLMMFIVVIGIIYYFIRYINKRLSKIYFIVDKMSQE
                     NYLKDTTESEETGYLVEYNEYFKEGIFSKINNCLYELNRSLKIKFIKLEKEKESVKSL
                     VTDISHQLKTPLASLKLYNTLLIEEELEEDEANEFLLTNKASINKLENLINSLVNISR
                     LEISMINIKKEDNDIKNTILNAVKSVTPKAKSKSITLNLNEFNSRIIPHDKKWTEESI
                     FNVLDNAVKYTQVNGEINISVEETANFFKIIIEDNGIGIEKSEFNNIFKRFYRGSADE
                     IESVEGSGVGLYLSRKILEEQGGNIIVSSKVGIGSKFSLFLTTM"
     gene            73526..74209
                     /locus_tag="ACGI5H_000224"
     CDS             73526..74209
                     /locus_tag="ACGI5H_000224"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HFG9695958.1"
                     /translation="MKILYTENLSKHYGKGESLVRALDNVDLEINEGEFVAIIGKSGS
                     GKSTLLHMIGGLDIPTSGKVYIDNKNIFTLKEEELAVFRRRKIGFIFQSYNLIPSLNV
                     WENVVLPIGLDGREVDEPFIKELLKSLGLENKHDVLPNTLSGGQQQRVAIARALATRP
                     AIILADEPTGNLDSKTSDEVMSILKSMSKKYSQTLVMITHDDSIAQMADRVIFIEDGR
                     VSKVGDKND"
     gene            74202..76589
                     /locus_tag="ACGI5H_000225"
     CDS             74202..76589
                     /locus_tag="ACGI5H_000225"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861587.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="FtsX-like permease family protein"
                     /protein_id="HFG9695959.1"
                     /translation="MINTTKIAKSNLKQNKSKSILIIITIILSTLMLSSIGIYIVDAG
                     AYQKENTIKYSGNYQGILANVDEKQADILSNHADVELTGKMNGVGVEKLEDDSNISLA
                     YMNEDALKLNSFEFIKGKLPSKENEIVLDSGALKALGYKNKDLGEKIKISYNDYKSDK
                     KIEKEFIISGILKTSEISEAGKYYYAIISESYMRNTRDMSQEDFNIYVKLNDKSNLSI
                     EQAKSKLNKIANDVGLDTINVAVNENYINALKPDMETIMGGVFVGLVIVLSSILVIYN
                     IFYISIVTKVQEFGKLRAIGATKKQVKNIVFKEGFILAGIAIPIGIILGYVLANIIIK
                     SFMDIDVKSSRLPVILSVVVISFISVVLSLLKPMKVASKVSIVDAVRYTGNKISNKSK
                     RKGYKNINLKRLSHANLERNKKRTYMTLASLILSGTIFITVSTALESFDAEKMAREHF
                     PYDIEVRLSGYEMNSDKNPKDNLNILQMDNPLSKDFFNQIKNMEGIKRIESARSVKIG
                     MEDYDVEFKYDLLQSINENDVKSLNKNIIDGKINLERLQTGDEIVITHVDTAKEMGVK
                     AGDKIRLTLYDGDKKIKKEFKVQAIAMGVPSFGIGKDFIDRTLKYDSTSSLGIYTEEG
                     KYQEIKDSIKKIAKNNGFLETDFIDSRIESNKATISFIKIMGYTLTGIIGVIGFMNLV
                     NTMITSIVTRKKELGMLQAIGLTNKQLVKMLNSEAMYYTSGMMIGSILFGGILGYIAV
                     IFLKKTGLSYATYSLPIVPILLMIVCILIAQFITTYLIGRSFNKESLIDRVRYSE"
     gene            76869..78011
                     /locus_tag="ACGI5H_000226"
     CDS             76869..78011
                     /locus_tag="ACGI5H_000226"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003431065.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alanine--glyoxylate aminotransferase family
                     protein"
                     /protein_id="HFG9695960.1"
                     /translation="MNKKINYAPGPTETRENVRLARAEKTTNPDIDIDFVEFYKKTCE
                     KFGNIIGTKNDVYILSGEGILGLEAACASLTEKGDRVLVIDNGIYGEGFKDFVTMYGG
                     EYVLFSSEYTKSIDIDELKAFLDEDSNFKYATVVHCDTPTGVLNDVSKICPLLKEYGI
                     LTVVDSVAGMVGERLSVDESKIDIILGGSQKAISAPAGLTIVGISQDAKNCIKNRKTD
                     VIGFYCNLNIWEGYYEKKYFPYTMPISDIMGLDKALDNILEEGIENVLNRHEKIAYSV
                     RKSIEEYGLELFLEEGYSNTVTAIKIPESIGALELTDYMLKNYNTLVATSLNQYMDTI
                     LRIGHMGENANLNKIEHVLNVLDKSLSALGFKGNGNLLNLFNKYYF"
     gene            78030..78554
                     /locus_tag="ACGI5H_000227"
     CDS             78030..78554
                     /locus_tag="ACGI5H_000227"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416384.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HFG9695961.1"
                     /translation="MEVTAKQKFTTKDMVETSLLIALVFIATKFINIRLPISINGGLV
                     HLGTAMLFISAIVFGSKKGALSGAIGMSLFDLISGWTLWAPFTFIVRGVMGYLLGKIA
                     WANGNNGNNFLINVIGICVSSIWMLFGYYVTEVILYGNFIVPLTSIPGNLMQVLIGLI
                     IALPISKVLKKCIK"
     gene            78654..79472
                     /locus_tag="ACGI5H_000228"
     CDS             78654..79472
                     /locus_tag="ACGI5H_000228"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729376.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF6597 domain-containing transcriptional
                     factor"
                     /protein_id="HFG9695962.1"
                     /translation="MLSVTRYSIKNVRLKPWVKFIWYFETKSNILLNNKLLPTDSIDI
                     ILNLSDVMEYKIENQDYIASNIHFNGIRDKHGFIIQHGNIRVIGISFYPFGLYPFLKI
                     PISEFNRQIVDLEAVSKLFAKKLEESLNPTKAIEKVVLCLEEVLLSILEEDLISNKYV
                     KLLNSFIYVNRYSNIKAFCDDTNINIKTLERICLKYTGYTPKILKRIYRFKMASNQLI
                     YNYKDDELFDFIYENEYYDQAHFIKEFKKFSGTSPIKFSGENKTIKENIKYSYL"
     gene            79550..79861
                     /locus_tag="ACGI5H_000229"
     CDS             79550..79861
                     /locus_tag="ACGI5H_000229"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416389.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="antibiotic biosynthesis monooxygenase"
                     /protein_id="HFG9695963.1"
                     /translation="MKIITEIVEFNVEENLSKEEFIEIVNDLELKFHSIQSGFIDTEL
                     LYDEKSQKWIMIQHWESIEDLKSVSSKMFKDSSTEKFRKALKNQTVKMNIIPQIKSWK
                     L"
     gene            complement(80038..80721)
                     /locus_tag="ACGI5H_000230"
     CDS             complement(80038..80721)
                     /locus_tag="ACGI5H_000230"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861583.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9695964.1"
                     /translation="MQKEVAMNKLIKDCVNFFNDCGFSYSICGGYALELFANMHIRPH
                     SDIDIWISDTDKEKSIQYMLNQGWDIYEPLGNYLLRPIIDLNKQHIEQICVFAIKPDC
                     SFIELKKVEDDNYKMNIQCDEQLQFDFIELIYNPQKDGKFLFSQNQRIIRDMDKARLI
                     TSDNIPYMAPEVVLFCKSIYIDRLGYQKDFDVTVPLLSQEQRDWLVNALITAYPDGHA
                     WIDQLANQY"
     gene            complement(80814..81464)
                     /locus_tag="ACGI5H_000231"
     CDS             complement(80814..81464)
                     /locus_tag="ACGI5H_000231"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416394.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HFG9695965.1"
                     /translation="MSFLGRKKEPDNTIQKILDISHKLFLEKGYEQTTIQDIVDNLDG
                     LSRGAIYHHFKSKDEIIKAITSRLYNDGFYGYEVKNDEGKTALEKLQYRLLHTYEQHN
                     KQDIFLMSSSLLRNPKYLATQFDEIINDIVPWIKALIEEGNQDNSMEVKNPEIAAQMF
                     GFLLNTWCIPTVYPGNPQQMIERFTLFGEQAAFMGISFMNDKIMCEYQKFVNKFSK"
     gene            complement(81629..83632)
                     /locus_tag="ACGI5H_000232"
     CDS             complement(81629..83632)
                     /locus_tag="ACGI5H_000232"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416397.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003824 - catalytic activity [Evidence
                     IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-amylase family glycosyl hydrolase"
                     /protein_id="HFG9695966.1"
                     /translation="MKSQKRFKILDIDVYLQPFESDIKKRMKHYEDMKSKTLKNYKDF
                     SSFANAHLYYGFHQTNDGFFYREWAPNADSLSLIGDFNNWNRKSHPLRKIGSGNWEIF
                     IPGQNSLPHKSEVKVQVTANGKTFDRIPLYIKRVIQKDFGGFNGQIWQPKTPFIWTDN
                     DFDLKNITSPLIYECHIGMSTESESIGTYNEFTEKILPKIKKAGYNTIQLMAIMEHPY
                     YASFGYQVSNFYAISSRFGTPEDLKNLINTAHSMGIAVLLDLVHSHAVKNTLEGINEF
                     DGSEHQFFHSGSKGNHPAWGTKLFNYGKPEVIHFLLSNIKFWLNEYHFDGFRFDGVTS
                     MLYHNHGLGVSFDSYEKYFSMNTDIEAITYLQFANELMKEIKPNSISIAEDMSGMPGM
                     CIPIKDGGIGFDYRLAMGVPDFWIKTISNLSDEDWDLGKMWYELTTRRPGEKNIGYCE
                     SHDQALVGDKTIIFWLADKEMYWNMEINSNNHVINRAISLIKLIKLITFSLAGEGYLN
                     FMGNEFGHPEWIDFPREGNNWSYKYARRQWSLSEDNNLKYKQLLNFDKSMLELTKYSD
                     IFIQNSHELIHMDNDKKILVYSKGKYLFIFNFHPNLIQSVDISKFQNTNYKTILNTDM
                     VEFGGNTKKENLRDYDVYFSSTPPSSKMPIASRTAIVLLDNGI"
     gene            complement(83785..84423)
                     /gene="recX"
                     /locus_tag="ACGI5H_000233"
     CDS             complement(83785..84423)
                     /gene="recX"
                     /locus_tag="ACGI5H_000233"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003431050.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombination regulator RecX"
                     /protein_id="HFG9695967.1"
                     /translation="MGIITKIEQQKRNDDRVNIYVDDKFFIAIFKELVYTFNLKKGNE
                     INEEELKPILDDEMYIKAKNKALNILSHADQSEKKLKEKLSSEFDENIIERVIDFLKS
                     YNLVNDSVLAQKIVNTNVNLNKCGKNRIKQNLYNKGINRSTINEAVSELDKDTEFENA
                     MYLAKKRYERVKKEDKKKIYQKISQHLSYKGFDYDIIKRVLNKLLNFDEYDI"
     gene            84699..85388
                     /gene="nadD"
                     /locus_tag="ACGI5H_000234"
     CDS             84699..85388
                     /gene="nadD"
                     /locus_tag="ACGI5H_000234"
                     /EC_number="2.7.7.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416411.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016779 - nucleotidyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0009435 - NAD biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="nicotinate-nucleotide adenylyltransferase"
                     /protein_id="HFG9695968.1"
                     /translation="MRSENLVKMAELKNTEKLEKFNRHKGKIKIGILGGTFDPIHYAH
                     LATAEFIRDKYDIDKIIFIPSGNPPHKLCITTDKYDRYNMTLLATESNEDFLVSKVEI
                     ERKKRTYTIDTLKYLKKKYKNADIYFITGADAICSVEEWKDVKKNFELATFIAATRPG
                     ISLLRSQETIEKLTKKYNADIITVYVPSLDISSTYIREQLNEGKSIRYLVPENVENYL
                     YENKLYQYGDD"
     gene            85389..85961
                     /gene="yqeK"
                     /locus_tag="ACGI5H_000235"
     CDS             85389..85961
                     /gene="yqeK"
                     /locus_tag="ACGI5H_000235"
                     /EC_number="3.6.1.41"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416414.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bis(5'-nucleosyl)-tetraphosphatase (symmetrical)
                     YqeK"
                     /protein_id="HFG9695969.1"
                     /translation="MNLENINQRLNQMLPVGRLSHSKNVAKCAEKLCEIYGCDKEKAY
                     LAGMIHDCAKYLSDKEIEDYVNKYEIYLDPIEDGNRSLSHSVIGAYICEYEFEVEDED
                     IINAIKYHTTGREDMSLLEKIIYIADLIEEGRKFPVVDTLRELAYGGKLDEALLTSFN
                     NTLMFVINKKEEIHPRTVMARNYLIKEKLL"
     gene            86078..86428
                     /gene="rsfS"
                     /locus_tag="ACGI5H_000236"
     CDS             86078..86428
                     /gene="rsfS"
                     /locus_tag="ACGI5H_000236"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416416.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0043022 - ribosome binding [Evidence IEA];
                     GO_process: GO:0017148 - negative regulation of
                     translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome silencing factor"
                     /protein_id="HFG9695970.1"
                     /translation="MTVEQMTKIAYDAIEDKLGQDTVIINIGKVSSLCDYFIITTASS
                     QRQVKAIADNVEDELAKLGLEPRGKEGQGTQTWVLLDYGDIMVHVFNEENRGFYNLEK
                     LWKDAPYIDIDTLA"
     gene            86782..89202
                     /gene="leuS"
                     /locus_tag="ACGI5H_000237"
     CDS             86782..89202
                     /gene="leuS"
                     /locus_tag="ACGI5H_000237"
                     /EC_number="6.1.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416419.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0004823 - leucine-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006429 - leucyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="leucine--tRNA ligase"
                     /protein_id="HFG9695971.1"
                     /translation="MSVYNFKEVESKWQKIWKDNNQYKMDTAQTEKPNYYTLEMFPYP
                     SGKIHMGHVRNYSIGDVVARFKKMEGYNVLHPMGWDSFGLPAENAAIKHGIHPHKWTM
                     ENIEEMKEQLNLLGISYDWDKEVATSTPEYYRFTQEIFLKFLEHGLAYKKKSYVNWCP
                     SCETVLANEQVVQGACERCKATVLKKDLEQWYFKTTEFAEELLNDLDILDGWPEKVKT
                     MQKNWIGKSTGADLVFDIDGTDKSMTVFTTRPDTTYGVTYMVLAPEHELVKELVAGTE
                     YEADVEAFVQKMHTMTEIERTAADVEKEGMFIGRYVINPLNGKKVPLWIANYVLVEYG
                     TGAIMAVPAHDERDRDFAEKYNLDIIDVITEDNKMINSEEFNGLDASEGFEGIIDKLE
                     KEGRGKRTINYRLRDWLVSRQRYWGCPIPVVYCDECGIVPVKKEDLPVLLPTDVEFTG
                     KGESPLTTSKQFMSTTCPHCGKPARREVDTMDTFVDSSWYFLRYVDSNNENEPFSKEL
                     VNRWHPVDQYIGGVEHAIMHLLYARWFVKAFKSMGMVDFNEPFKNLLTQGMVLMDGSK
                     MSKSKGNTVSPMDIIDEYGADTARLFVLFAAPPERDLDWSEQGVDGCFRFLNRVYRLV
                     DELADVVKKDVEFGELNSQDKDMRYTIHSTLKKVTADLSEKFGFNTAISALMELINDM
                     YKYKELDNINEAVIKEGVQTIVTIIAPFAPHLGEELWTMIGKEGSVFDIDWPKYDEKA
                     LVKDEIEVVVQVNGKVRGKLTVNSNISKDEMEKVALEDEKIKGLVEGKTIVKVVAVPK
                     KLVNIVVK"
     gene            90055..90723
                     /locus_tag="ACGI5H_000238"
     CDS             90055..90723
                     /locus_tag="ACGI5H_000238"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861580.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VanZ family protein"
                     /protein_id="HFG9695972.1"
                     /translation="METVTNNQSGVEIQLSLFEAIKDLLLINPIFLLGIILIGIFLVV
                     IFKKNSDIPKVKTSILSLAMYYYLCLTLSHIVGIPTFSEYIRLSQLGETFFNPNINLI
                     PFSDGFSLSFILNILLFVPLGFLCPLISKTFERLRNTFLIGFGLSLFIETIQLFTLHR
                     ATDIDDLLTNVIGTIIGYFCFKLIAKLRIVKLHSDDDSMEQDYTVCIPIAIIIVALIL
                     GFFS"
     gene            90763..90843
                     /locus_tag="ACGI5H_000239"
                     /pseudo
     CDS             90763..90843
                     /locus_tag="ACGI5H_000239"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005541856.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
     gene            complement(91206..91478)
                     /locus_tag="ACGI5H_000240"
     CDS             complement(91206..91478)
                     /locus_tag="ACGI5H_000240"
                     /inference="COORDINATES: protein motif:HMM:NF012798.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA];
                     GO_process: GO:0015074 - DNA integration [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HFG9695973.1"
                     /translation="MSKHQFKSVSTFFTKKNVSQFYKKNNLKKIRIHDLRYTSATLLL
                     LGGTNMKVVSERLGHTDIKITMNRYSHVLKEMDKEASDNLSELLFK"
     gene            complement(91508..92323)
                     /locus_tag="ACGI5H_000241"
     CDS             complement(91508..92323)
                     /locus_tag="ACGI5H_000241"
                     /inference="COORDINATES: protein motif:HMM:NF026010.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Arm DNA-binding domain-containing protein"
                     /protein_id="HFG9695974.1"
                     /translation="MNIKSAFIRKRGEKFYVYVEYIEETTGKIKQKSYGSYEKKKDAE
                     KHLIEIKSTINNNKFVAPKDMTFVERCYKYMDMNKNNWSPYTVTNTKSWVKNYIEPLF
                     KNLKLTEVNPSSVQAFVNYNFNNSTFTSAKVRYSFLSSVIREAYRLREIQENSCDFIK
                     LPSKEKYSTNEIYNRKEVLLLIEKLLSNNIEIPILLMLLLGLRMGEATGLRWSDVDLD
                     NNLINVNQILVYSNGKISFKEPKTPKSKRALSAPKELIEKLKIKKLRQSKLKL"
     gene            92539..93909
                     /locus_tag="ACGI5H_000242"
     CDS             92539..93909
                     /locus_tag="ACGI5H_000242"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861578.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall-binding protein Cwp29"
                     /protein_id="HFG9695975.1"
                     /translation="MKLKKLLSLGLVSMFVAGFPISANALDKIDKIQGADKYETAGII
                     ADKQSYTTAILINADSTMADGLSASGLAGATNAPILLTKKNNIPNATLKRVEKAKKVY
                     IIGGESSIDKATETFLKDKGIETRRLQGNDRIKTSYNVAKEINSINKVNKVILTNAFK
                     GEPDAMSAAPVAVRDKAAIVLTDGKSVPFNTTGIESYAIGGTSSMSDSLVNDTNSTRL
                     GGVDRYDTNKKIVNKFYNGAKEFYIASGTDLVYALVASPMAKNNPIVLVDIGSNKDIL
                     KNAAKVTGIGNLSDKIMLECENTINNISLPSSNKNIICGLKIDFDSNHIIWQDKGSYL
                     ECYDDNLEYYTEKYKDPTVPINIENTSTQNLDVTKLKVYGEANSTLYMGQYAKIKMDF
                     NSFGVLKPGEKCTIYLDIISLDPSRSMTLTFSYVGDKENYKYEQGLASRILFYNPDGE
                     DFFEYK"
     gene            94203..94361
                     /locus_tag="ACGI5H_000243"
     CDS             94203..94361
                     /locus_tag="ACGI5H_000243"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003431040.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9695976.1"
                     /translation="MDNFLQGILASLSASLIVYIASKLFRKRKKPLKAATKSGWEFDL
                     KIRFHKTK"
     repeat_region   94647..95139
                     /inference="COORDINATES: alignment:crt:1.2"
                     /inference="COORDINATES: alignment:pilercr:v1.02"
                     /rpt_family="CRISPR"
                     /rpt_type=direct
                     /rpt_unit_range=94647..94676
                     /rpt_unit_seq="gttttatattaactatatggaatgtaaatt"
     regulatory      complement(95280..95377)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF01051"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="cyclic di-GMP riboswitch class I; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /bound_moiety="cyclic di-GMP"
                     /db_xref="RFAM:RF01051"
     gene            95679..95987
                     /locus_tag="ACGI5H_000244"
     CDS             95679..95987
                     /locus_tag="ACGI5H_000244"
                     /inference="COORDINATES: protein motif:HMM:NF015898.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0045892 - negative regulation of
                     DNA-templated transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="BlaI/MecI/CopY family transcriptional regulator"
                     /protein_id="HFG9695977.1"
                     /translation="MSKDVADEIEKTYAWKHTTTITLLARLTKKGFFISQRIGKHVHY
                     RVLIKEKEYLKIEGKRIFGGLHNNPLSELISKLHDGEEITEEKIIEIGNWIKSWKDED
                     "
     gene            complement(96165..97160)
                     /locus_tag="ACGI5H_000245"
     CDS             complement(96165..97160)
                     /locus_tag="ACGI5H_000245"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003431031.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="asparaginase"
                     /protein_id="HFG9695978.1"
                     /translation="MSIKKKVAIVFTGGTISMTVDDKVGAAIPTLSGEQILSMVTNID
                     KVADVEVFNFDEIPGPHITPYRMMELKNYVNDLLARKDITGVVITHGTDSLEETAYFL
                     DLTIDNIKPVIVTGAMRSSSELGYDGSSNLSASVCTAVSKDAMGKGVLVVLNNEVLLA
                     SEATKTNTLSLNTFKSLTSGPLGIIDCNELVLTRDIVNRTIIDTDKVESKVALFKAYV
                     GENADFIRFAVDSGYKGIVIEAMGRGNIPPQMLSGVEYAREKGLPVVIVSRCHSGRVF
                     DSYGYFGSGRDLKNLGCIFGGDLPGQKARIKLILALGKTDNLDEIKDFFEKGIYC"
     gene            complement(97281..98909)
                     /gene="aspD"
                     /locus_tag="ACGI5H_000246"
     CDS             complement(97281..98909)
                     /gene="aspD"
                     /locus_tag="ACGI5H_000246"
                     /EC_number="4.1.1.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416436.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0047688 - aspartate 4-decarboxylase
                     activity [Evidence IEA];
                     GO_process: GO:0006531 - aspartate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate 4-decarboxylase"
                     /protein_id="HFG9695979.1"
                     /translation="MKNHTYKEIKNIYGKISPFEFKDKLIDIAKYTAKENNRELLDAG
                     RGNPNWTCSTAREAFFTFGHFAITETRSNWDLGHLAGMPQKKGIKERFFKFINENIDM
                     PGAYLARDIINFGINELGFDGDEFVHELADGIIGDNYPLPDRMLPHMEKIVHDYLVQE
                     MKYDISGKYGDVEIFAVEGATAAMCYIFDSLMANELLKKGDTIALMTPIFTPYLEIPN
                     LPRYDFKVVNINANEVDEKGAHTWQYTKKELEKLRDKSIKALFVVNPNNPASIAMDET
                     SCNNLIDVIENYNKDLMIISDDVYGTFVEDFSSLMSKLPYNTVGVYSYSKYFGVTGWR
                     LGTFALHKKNVFDKKINDLTGELKKSVDKRYSDMSLNPSSLSFMERVVADSRLVALNH
                     TAGLSTPQQVQMAFFSAFALIDKVDAYKKLNMSICHRRQKLLFEALELPINENKNNAA
                     YYTQFDIEEWAKLNYGEDLFKFISKTASPVDVLYKLANDYSVVLLSGNGFYGPEWSIR
                     ISLANLYDEAYTKIGKAIREILNGYIVEWQKIKK"
BASE COUNT        38162 a        11102 c        16833 g        32913 t
ORIGIN      
        1 taaatcattt tttgttttta tataagtaaa taaatttagt gaaatttaaa taaaatatct
       61 tatattaaag tattttgttt aaaaaagctt gaaaaatttg aaatataaat atataatttg
      121 agttgataga ttaaaaaatt atctttaaac gatacagaga tatcgtaaga caattgctaa
      181 attacactgt atatttttta tataagagct tcttgtcttg tgatgagaag tttttttgtt
      241 gtttaaattg aaattttaaa taaaaataaa tttataaaaa attaaaagaa aggagtagat
      301 ttgtcaaata gatatattat atctttgaca ataattatga tatggtagaa aaagctcaat
      361 taatggatga aaaggcaata gcaagagcaa ttactagaat aagtcatgaa ataattgaaa
      421 gaaataaagg tgtagaaaat ctagttttag ttggaataaa gactagaggt gtgccaattg
      481 caaatagaat ttctaagaaa atagaacaaa tagaaggaac aaaagtagat acaggagata
      541 ttgatataac tttgtataga gatgatttgg aaaaaattca tgttgaacct gtagttaaag
      601 gaacttattt agattttaat gtaaatgata agacagtagt tttagttgat gatgttttat
      661 acactggaag aactgtgaga gcttcactag atgctattat agatatagga agacctaaat
      721 caatacaatt agcagtgcta gtggacagag ggcatagaga gttgcctata agagcagatt
      781 atgtaggaaa aaatgtacct acttctagac atgaaattat atctgtcagt ttattagaaa
      841 ttgatggaga agattcagtt acaatcaaag aataattatt tttaagtatt atataaaagc
      901 ttagcattga atagtcaggg aggaggataa agcttacata gattgcacaa aataaatatt
      961 ataattttat ggatgtgagt cttaatgtag tttttattct cctttatttg agtttttgat
     1021 gtcgtaaaat gtaaaataat gataaattat ataataagta tatagaggtt aaaaaataga
     1081 atctagggaa tgataattaa ttaaaaggta ttaattaaac agaggattta tttatatata
     1141 ataattttgg aggtttttat gaaaaaaacg ataatgtctt tacaacatct attagccatg
     1201 tttggagcga cagtattagt tcccattttg acaggtttta atccgtcagt tgcaattttc
     1261 tgtgctggtg ttggtacatt gatatttcat ttttgtacag aaggaaaagt acctgccttt
     1321 ttaggttcaa gttttgcgtt tataccagtt atactagcag ctaaagaggc gtatggtgga
     1381 gatttagcat atgctcaagg tggtataata gtagcaggat taatttatat tataatgtcg
     1441 attatagtaa aagtagttgg tgtaaataaa attaaattat attttcctgc acaagttaca
     1501 ggagctatga tagtagttat aggattaaat ttattgccaa cagcttttag tatggcttca
     1561 gccaattttg tgatagcatt tataacttta gcaatagcaa ttttaaccaa taagtttggt
     1621 agaggattta taaaacaatt aggaatatta atagcagttt tttctgggta tataatctgt
     1681 ttgatattaa gattagtaga tataactact attacagaag caagtttatt tgcaatacct
     1741 aactttacag ttcctaagtt cagtttagga gcaatagtga ttatatctcc agttgtatta
     1801 gctgtattta tggaacatat aggagatatg actactaatg gtgctgtagt aggtaaaaac
     1861 tttatagaaa atcctggatt aaatagaaca ttacttgggg atggatttgc gactatagtt
     1921 gcagggtgtt taggaggacc agcaaataca acttatggag aaaatacagc agtacttgct
     1981 ataactaaaa actatgaccc ttcaatactt agacgtacag caatatttgc tatattgctt
     2041 gcatgtgtag gcaagtttgg tggatttctt caaagtatac caggttcagt tatgggtgga
     2101 attagtataa tgctattttc gatgataact tatgtaggat taaaaactat aagggacagt
     2161 tcttgtgtag aaagtaaaat aaatatatta atcatagcag ttatattatt aataggtctt
     2221 ggaacaacat atttatctaa taaaggtatt tctgttggaa tccctataac aagtacagta
     2281 aagataactg gtcttagttt agctgcaatt gttggaattg tattaaacag aattttaaat
     2341 aatcaggact ttaaagttga agaagaataa atttaaagaa taagttgtat attgaataac
     2401 taaaattagt taattttcta tagacatttg taattaatgt tgatataatg attaaaaata
     2461 aatgaaagaa agggcaaggt aactaggaca atgagaatat aatctatttt ttataattta
     2521 aagtattgta atttttgaaa agcctatttt ggtggcttta tttgcaatgc ttaaattaag
     2581 gagagtagat tatagtctat acgtttattt gttatgccta tttatagaat ctctccttat
     2641 atttaagtgt gttaaggagg gattttttat gttgttagta aaagtagaga atttaaagaa
     2701 atattatgca gataaattaa ttttggatat agataaactt gaaatattag aaaatgacaa
     2761 aataggtcta gttggttcaa atggtcaagg aaaaacaaca ttattaaaag caatattggg
     2821 agaaatagaa attgatgaag gatatactta ccttacagaa agctattctt atataagtca
     2881 gagtgaaaat aatattgaaa catgtagtca tagtaaggag aagagtcttt taaatgctcc
     2941 agataaattt gaagaacact tatcaggagg ggaaaaggtt aagttaaaaa tagcagatgc
     3001 gctgagtaat aagaaaaata tcataatagc tgatgagcca acttcaaact tagataaaaa
     3061 aagcattggg gttttggaag atatgtttaa aaggcatgag ggagcattat tattaatatc
     3121 tcatgataga cgttttctgg atgagttatg tacaactata ttagaactag aagatggaaa
     3181 actaaaagct tacaaaggca attacactga ttatttaatg caaaaagatg aagaagtaaa
     3241 aagagctgat tttgagtatc aagaatatgt taaagagaaa aaaaggcttg aaaaagctct
     3301 tttatataaa aaagctttaa gtgatggcat aagaaaaaca ccaaaaagaa tgggtaattc
     3361 agaagctagg ttgcacaaaa tgggtggtca gactaataag aaaaagttgg actcaaatgt
     3421 gaaggctata aaaagcagaa ttgataaact tgaggtaaag aataaaccta aagtttctaa
     3481 agaaatgaac attaagattc aagatggtat ggagataatt agtaaaaatc tagtagaggt
     3541 aaaagatatg actctaaagt tagaaaataa gctcctgtta gataatgttt cctttaagat
     3601 aaaaagaggt aaaaagatag cattattagg tgataatggg tgtggaaaaa gtactctgat
     3661 aaaagaaata ttggctgata aaaatgacaa tataaaaata aataacaagg taaaagtagg
     3721 ttattttgac caaaatcaaa gtttattaga tgaggaaaag agtgttctat acaatactaa
     3781 agttaatagt tcatttgatg aatcttttat aaggataaac ttaagcctat ttgggtttaa
     3841 aggtgatgat gtctacaaaa aagtaaaagt acttagtggt ggagaaaagg taaaaatagc
     3901 actatgtaaa ataatattgg aagataataa ttttttagta tttgatgaac caacaaatta
     3961 cttagatata aaatctatgg aagcactgga aaaggcactg ataaatactg ataaaactat
     4021 gcttatagtg tctcatgata gagtatttgt atcacatatt tgtaactata ttatagagat
     4081 aaaagatgct aaaataaggg agtttgattg taattatgac gaatatacaa ttagcagaaa
     4141 taaaaaaact cctagtagag aaaaccaaat caaaaaagaa aatcttctag tattagaaaa
     4201 tagacttaca actgttatat ctatgttatc tatagaaaaa gataatctaa aaaaagaatt
     4261 gtatgaatca gaatataatg aattactaaa acaaatcaat aaattaaaaa atagctttta
     4321 gtgttaactt tttaattaca tctatataag aagactgaaa atatttgttg ggaatataag
     4381 tatagttatt aaaacagaaa agtattttgt tagaaaatta aaagtaagct aattagaaag
     4441 tggccttatt attgtacttt ataagaaggc cactattttt atttagaatg ataatgtgta
     4501 gttgtctaac atttattttg tatttagtgc agaatttatt cagatttaac cttaagcttg
     4561 gctactgttt cttcttcagg agtaacataa atagtactgt tagtttcata aataaccata
     4621 cctggtttag aaccactagg ttttttcaca ttttttctct tagtatagtc tacaggcacc
     4681 tgagaagaaa gttttgactt actaaagaat gctgctagca tagctccttc aaatacagta
     4741 ttatcaggga cttccttacc agcacacttt attattacat gagaaccagg aatattcttt
     4801 gtatgcatcc ataagtcatc attatcagca agtcttagtg taagatagtc attttgctta
     4861 ttgtttttac caaccaatat tttaaatcca tcagaagaaa caaattcatg aggttttgta
     4921 gatgggatag tatccttttt actgtttttc ttttgagtct tgatgtatcc aaccttagca
     4981 agttcttctt ttatatcttg taattcagct aaattttcac agttttcaat acttaaaatt
     5041 atgttttcta agtaatctat ttcttcctta tttaaggaaa tttgatgaga tatctcgact
     5101 ttagcatgtt tcattttgtt atacttttta aagtattttt gagcattttc agatggtgtc
     5161 aagtttttat ttaattctat tgttacatca ttacaatttt catcatagaa gttagcaact
     5221 tcaatacttt ccataccttt ttctaccata taaatatatg aagtaatcaa ttctcctttt
     5281 atcttataaa tgtctgcatt ttcggattct gataattctt cttcttgttt tttaagttta
     5341 ttataaagtc tatcaagctt aacagatata ctcttcttta aatcagatga acgttgatta
     5401 attctatctt taatatcctt agttctatag aaatcttcca gaatacgaga catactatcc
     5461 ttatttatat atgataaatc gctaaataat gtaaggttta tacaactgaa atcaactacc
     5521 ttatccacct ttttatctat aataatgcaa ggagagtatt tgttagaatt tatatcattg
     5581 aataaattac aaaatacttt gtgtaaagaa tcaaattgtt catcagatat atcctttatg
     5641 atagcatttt gatttacacc tgctctgtag caaatttctt tagctataat agggcttata
     5701 cctagaaatt tagaatatat agacttaaag ataggtcctt ccaattcctc taggttttta
     5761 ataaacaaat ccttagatat atcatcaaga gggttgagtt tgttttgttc tggtggcaat
     5821 gaataatcat gaccaggtaa aacttgacga actctactta tgctaaaagg gactcttttt
     5881 atagaatcta taattttatt ttcttcacca tgagttatta ttatgttgct atgtcttccc
     5941 ataatttcaa tcataatatt tttaactgtc ttttctttta attcatctaa agattcaaca
     6001 cttattttta ttattctttc aaaacctatt tgagaaattt ctactatatt tccaccttgt
     6061 atgtattttc taagtaacat acaaaacata ggcgctttta gagggttttc tttttgataa
     6121 ttacttgtaa gataaactct aggatttgag gcacttgcac ttaaaaccaa tctaaaattt
     6181 tctttattat ttcttatatt aaaaattacc tcatcatctt caggttgatg tatcttatct
     6241 atttttccac ctgtaagttt tgatgataat tcatcgacta ttgaatgtat aactaatcca
     6301 tctaatgcca tttatagcac ccctttcttt gaccaaaatg agtcagtaaa ttaattatac
     6361 acataatata cgctttgtga ctagggggaa tttaaacaat agagattaat atttaaattg
     6421 tataattatt tatatttatt agagaggaaa ctttattttt aaaattaata atttaaagta
     6481 gattaaatat aaagtaaata tagtataatt attgtgtaga gtataagcta tgaaagtata
     6541 tgaactttac agaaaaaatc aattttaagg ttctatagta tataaatatg aaagaaggtt
     6601 gaaaaaatga gatttatcga tttaagaagt gatactgtta ctatgcctac tgacgaaatg
     6661 agagaagcta tggcaaaggc tcctgttgga gattcaatct ttagagatga ccctactgta
     6721 aataaacttg aagaattagc agcagctaaa gttggaaaag aagatgctat tttccttcca
     6781 agtggaactt ttgggaatca attagctcta tttactcatt gcctaagagg gcaagaaata
     6841 attattggta aaggttatca cattgtgact catgaggttg gggcacctgc tgtaatagct
     6901 ggagttcagc ttagaactat agatgaagac gaaagtggag ctctaaatcc tgaacttgtt
     6961 gaaaaggcaa ttagaagaga tgacatacat gaaccacaga cagggcttat atgtgtagaa
     7021 aatgcatatt caggtggaac agttgtgagt cttgataatt taagagaaat taaaaaaata
     7081 gctgagaaac ataacttacc agtacattta gatggagcaa gattatttaa cgcagcatta
     7141 actttgggtg tagaagctaa agaaatagca aagtgttgtg atagtgttat gttctgtgtg
     7201 tcaaaaggtt tagctgcacc aatgggttct atacttgctg gaaataaaga atttatagca
     7261 aaagctagaa gaaagcaaaa agttatgggt ggaggaatga gacaagtagg tatagttgca
     7321 gcagctggta taattgccat tgaaaaaatg actttaagat tgaatgaaga ccatgaaaat
     7381 gcaaaatatt tagcttgtga attaaataaa attgatggca ttgaagtaaa caatgttaat
     7441 ccagatataa gtatggtatt ttttaagatg agtgaagata ttataaaaga ggatgtttta
     7501 ataaaagaat tttttgaaag aaatataaaa attaataaaa tggaaaatgg tgaatataga
     7561 tttgtaactc atgtagatat tactaaggaa gatttagact atgttttaaa aacacttaaa
     7621 gaattaatag gtgtatgtta atagatatct actagaagga ttatagctag ttaccagatg
     7681 tttaattaaa aaattcatag acagtttaaa taaaacatac ataaaattca tatagaaata
     7741 ttaatatata aacatagaaa gaactagctt aaaaacataa tataattacc ctaattgtaa
     7801 tggcaactct ccctcacatc ctcaaattat agttgtcatt acaaaacttt tcccataaat
     7861 tataagttta tgggaatttt tttatgttat aatagtttaa gtgttaattt acgaaggagc
     7921 gatacttatg aaattttgga aactacatgg aataggaaat gattttatag caatagatgg
     7981 aagattcgac cagataaatc catctgatta tactgcttta gcaaaaaaag tatgccatag
     8041 aagattttct gtaggagcgg atggattgtt agttgtgaaa gattcaaaag ttgcagatgt
     8101 agaaatggta tattataatt ctgatggttc aagagcagct atgtgtggaa atggccttag
     8161 atgtttttgt aaatttgttt atgataattg tatagttaaa aaagaaagtt ttacagtaga
     8221 tacattagat ggtataaaag atataaaagt aaatcttact aatagagaaa taaactctat
     8281 aagagtcaat atgggaaaag gaagttttat agctaaggac gttcctgtac ttacaaataa
     8341 agaacgtttt gtgcaagaaa gtataaaggt tttagatagg gagcttaaag ttacttctat
     8401 gttgatgggg gttcctcata cagtagttat agtagatgaa ttagatgtag atgatgtttg
     8461 taaatatgga aaagagattg aaaataataa aatatttcct gaaaaaacga atgtaaattt
     8521 tgtaaaggta gaagataagt ataatataca tgtttatact tgggaaagag gttgtggata
     8581 tactttaggt tgtggtactg gtatgactgc atcagcaata gtgtgcaatt tacttaatat
     8641 ggtagaaagt agtgtaaatg taacgtctca aggtggaaca gttaaaatag atgtaggaga
     8701 tttctcttat atgacaggtc cagcagtaaa aatatgtgaa ggtattttgg aggtttaatt
     8761 aatggctata agtatgactg gttttggaag aggagaatac aaggatgata attattactt
     8821 tttagtagag tgtaaaacga taaatcataa gtattcagat ataaacatac gtcttccaag
     8881 aaaaatttca tttttagagg ataaagttag aaatttagta aaaaattatg taaaaagagg
     8941 aagagtagat ttatacataa agtttgactt attaggcaaa gaagatgtaa acttaaattt
     9001 tgatgaggga ttagcatctc agtatataga catactaaaa gaaataaaaa ataaatttga
     9061 tattatagat gatattagcg ttatgaatgt tgcaaagttt cctgatattg tgaaaataga
     9121 agaaaaggaa gaagatgaag atttattgtg gtcaatgttg aatcaagcag ttgaagatgc
     9181 attaatcaaa ttaagagaaa tgagaagtga agaaggtaaa aaattagctg aagatattgc
     9241 catgagatgt gatttattaa aaaatcatat agaagagatt gaaaaatatt caagtagtgt
     9301 tgtagaagat tatagagaaa aattgaattt gagaataagt gaattactgg atgacccaag
     9361 tataatagat gagaatagat tagcacaaga agttgcaata tatgcagata aaagcagtat
     9421 aacagaagaa atagttagat ttaaaagtca tatagggcaa cttaaaaata ctatatttaa
     9481 agacgactct ataggtagaa aaatagattt cttaatacaa gagatgaata gagaaactaa
     9541 cactataggt tcgaagtcat ctgatataaa tataactaat ttagtagtag aagtaaaaag
     9601 cgaattggaa aaaataagag aacaaataca aaatatagag taagaataca atattagaag
     9661 gggaatgctt aaatgtttgt gaaaaaagga ttattgctag ttgtatcagg accatcaggt
     9721 gcaggaaaag gtactatttg caaagaacta cttaaagaaa atgatacaat aaaactttct
     9781 gtatcagcta ctacaagaaa acccagaact ggagaagttg atggagtaaa ttatttcttc
     9841 ataagtaagg aaaagtttga agagatgata gaaaaaggtg agtttttgga gtatgctcaa
     9901 atttatgata atttttatgg aactccaaaa gcggcaataa tggaatgttt agaaaaagga
     9961 caagatgtat tactggagat tgaaatgcaa ggagcaaaac aaataaaaga agtttgccca
    10021 gagggagtat ttatatttgt actaccacca tcacttaaag aattaaaaaa tagaattgtt
    10081 ggaagaggta cagaaacaga agctgaaata gagaagagat ttagctgtgc atatgaagaa
    10141 attaaaatga ttaaggatta tgattatttt atatttaatg aagatgtaaa aacatctgct
    10201 aaagaaatag aaggtataat atcatctgaa aagaataaag ttagcagata taaaaatatt
    10261 ataatagaga aatttaagga ggaattataa ttatgttaaa accatctatc aatgaggtac
    10321 tagaaaaaat agacaacaga tactatttag tagggactgt ttcaaagaga gcaagaaaat
    10381 taattgatgg agaagaacca tatgtttcaa ataaaactaa ggaaaagcct gtatgtgtag
    10441 caactaaaga agttgcaagt ggaaaaataa catatagatt attgacagaa gaggaaatag
    10501 agatagaaga agctagacat catgctgagc aacaccaaca aatttcagaa gaggagtaag
    10561 gtcatgctaa aagataaaac tgttgtaatt ggcataagtg gcggtatagc tgcatataag
    10621 gcttgtgatg ttgtaagtaa gttaaaaaaa ctaaatgcaa atatccatgt tataatgaca
    10681 aaatcagcaa cagaatttgt taaaccactt acatttcaat cgctgagtca aaattatgta
    10741 gtagaagata tgtttgaaga accaaaaact tgggaagttg aacatatatc attagcaaaa
    10801 aaagcagatt tattcttaat agtgccagca agtgcaaatg ttataggcaa gattgcaaat
    10861 ggtatagctg acgatatgtt gacaactact gttatggcaa caaaagcaca ggttcttata
    10921 gcaccagcta tgaatactaa tatgtatgaa aatccaattg ttcaaaaaaa tatacaaact
    10981 ttaaagagct ttggatataa atttattgaa ccggaaagtg gaaggcttgc atgtggagat
    11041 attggaacag gtaaactagc taatccagat ataatagtag aggaagtttt gactaatctt
    11101 actaaagagc aagatttaaa aggtcaaagt atgatagtta cagctggtcc aactgtagag
    11161 agtatagacc cagtaagata tttaactaat aggtcttctg gtaaaatggg atattctata
    11221 gcaagagaag ctatagctag aggtgctgat gtaacattaa tatcaggtcc tacaaatctt
    11281 tctattccac aaaatcttaa aaaatttgtt caaatagagt cagcacaaga tttgtatgaa
    11341 gcagtagtat caaatttaag tgaaaataaa atagtaattc aaagtgcagc agttgcagat
    11401 tataaaccaa aaacttattc tgacaaaaaa attaaaaaga agaatgatga tttatcaata
    11461 gaactaagta gaaattatga tattgcttat gaaataggaa aaataaaaga agataagata
    11521 ctaattggat ttgcagctga aactaatgac cttatagaac atgccaaagg aaaaataaaa
    11581 aagaaaaatt tagattttat tgtggcaaat gatttaacta aagaaggtgc tggttttaga
    11641 gctgatacta atattgtaaa aataatagat gtagagggaa atattactga gtatcctaag
    11701 atgaaaaaag aagaagtagc caatgttatt ttagataaag ttaaagcgtt gcttgagaaa
    11761 taagaccttt tttaaatatg atatttgtgt attttatcac agctaaagtg gctgaaagct
    11821 gcaatttaat tttagcgagt aaaaactcgc aaatgtcagt taaattgtag ttttcagcat
    11881 ttattttgtc ataaagtata aaatataatt aatagttaat tattaaaata aagttaatat
    11941 taataacttg aaattgctta taaattctga gattttaata tcttgtaaag tatattaaaa
    12001 tatgaacaat atattaaatt taagtagagg ttttataatg aaaaaatatg caaaggtaat
    12061 agttagaagt aatactatat atacagataa tttatttaca tatcaaattc ctgtattttt
    12121 atctgatgta ataaaaattg ggcacagaat attagtacca tttggaaaag gtaataaacc
    12181 aacagaagcc tttgtatttc aatttacaga tagcttagat gaaaaaataa aaataaaaga
    12241 aattattgat atattagatg aaaatccgat atttagaaaa gaagatttag agttggttta
    12301 ttggatgaaa aatagatatt tgtgtactta tatagaatgt ataaatttga tatatccaaa
    12361 gggatacaaa ttaaataatt ataaagtagt cctattaggt gaaagtttaa gtggattaaa
    12421 tgatattgaa ttgaaggaaa aaatatcaac tttaagtgat aaaaatagag aaatagtaga
    12481 gaaagtgatt gatagtaaag gtaaaattaa ggttgataag ttaaaatata taccaaactt
    12541 aaatagttct ttgtacacaa tgaataagaa tggaattata aaattatgtt gggaatataa
    12601 aaatcacaaa aatgaaaaga aggtatgtta tatatctttg agtttagaaa gtgataagat
    12661 tgacgattat atagagcaaa ataaaataaa tgtgggaagt aaacaaaaag agatattaag
    12721 ttttcttaaa aataatgaaa atgtagagat aaatgattta ttggatttat taaatgcttc
    12781 aaaacaaagt ataaattctc taagtaagaa aaagctaata accctagaat ttaaggatta
    12841 ttatagagag ccaaaaagta tttacaaatc cgtactaaaa agtataaaat taaacaatga
    12901 gcaacaagaa gcagttgatg agataaagtc gaatatgttt gtagatgata aaaaaccata
    12961 cttaattcat ggagtaactg gaagtggaaa aactgaagtt tacatggaaa taatagaatt
    13021 tgctctaaat caaggcttag acagtatatt cttagtacct gagatagcat taactcctca
    13081 aacaatagat aggctaaaga gtaggtttgg agatttggtt ggagtgttcc acagtaaact
    13141 atctgaagga gaaaaacatg atgtttacaa agctgtcaaa gcaggtaaag taagagtgtt
    13201 aattggagct aggtcagctt tatttgcacc ttttaattcc ttaggcttaa taataattga
    13261 tgaatgtcat gagtcatcat ataagtctga gaagaatcca aaatttaatg ctatagaagt
    13321 tgctagattt atggcattaa aaaataatat aactcttatt ttaggttcag caacgccctc
    13381 aattgaagag tattataggg caaaatctgg agaatacaaa cttataaata taaaaagtag
    13441 agcaaatgat aagcctcttc caaacattga agtggtagac atgaaagatg agttagataa
    13501 aggaaataga agtatattta gtttgaaatt acaaaaagaa atacgttatg cgattgaaga
    13561 aaataatcaa gtaatactat ttttaaacag aagaggttat gcaaattttg tatcttgtag
    13621 aaagtgtgga tatgtgtttc aatgtgaaaa ttgtgatata tctttaactt atcataagaa
    13681 aagcaatact ggaagatgcc actattgtgg atatgagaaa gaaattccaa aagagtgtcc
    13741 tgaatgtaaa agtacttatg ttaagccatt tggagttgga actcaaaaaa ttgaagagga
    13801 attaaaatat atttttccag atataaaaac tttgagaatg gataaagata caacttcaaa
    13861 aaaaggtgct ttagatgaga tactaaataa atttaaagat aaagaagcag atgtacttat
    13921 tggaacacag atgttaagta aagggctgga ttttgagaat gtaactttag taggtatttt
    13981 gtctgcagac atgatattaa attttccaga ctttaaaagt tttgaaacta catttcaatt
    14041 gataactcaa gtctctggaa gagcagggag agctgataaa gagggaaaag tagtacttca
    14101 gacttatgac actgaacact atgctattaa gcatgctatt gaatatgatt atgagggttt
    14161 ttatgaagat gagataaaaa taagaaaagc atttggatat tctcctttta ataatatgtt
    14221 aagtgtagtt gttagtggtg aagatgaaag actagtgata aaaaatataa aaaatatgca
    14281 tgcatcattg atttatttat tagaaaaaag gggtataaat gatttaggat ttatattagg
    14341 tccaaatcca tgttcaatat caaaaataaa tcaaaattat agatggcaaa tactctttaa
    14401 agatgaaaat attgaaatta atctcttaaa gggtataata aaatatatat gtataacaaa
    14461 acgagatttg atatttgata agaatatcaa tgtatctata gatattaatc caaacagtgt
    14521 attataaatt taggaggaat tataatggct ttaagacaaa tagttcaaat aggagaacca
    14581 gtattaagaa aaaaatcaaa aaaggttgaa aaaattgatg aaaagataat acaattatta
    14641 gatgatatgg cagaaactat gtatgatgca gatggtgttg gactggctgc acctcaagtt
    14701 ggaatattaa aaagagtagt agtaatagat attggagaag agcttataga acttataaat
    14761 cctgaaataa tagaaacatc tggggagcaa atagatgagg aaggatgttt aagtgttgtt
    14821 ggagaagcgg gaaatgttag aagaccaaat tatgtaaagg tcagagcttt aaatagaaat
    14881 ggtgaaacaa tagagttaga gggagaagaa cttttagcta gagcattttg tcatgagata
    14941 gaccacttag atggaatttt gtttgttgac aaaatagaaa agtagtagga gttgatttga
    15001 tgaaaatagt atttatggga actcctgata tagcagttcc atgtttacaa aaaataatag
    15061 atgagaagta tgaaatattg ggtgttgtaa ctcaaccaga taaaccaaaa ggaagaggta
    15121 aaaaactagg tatgagtcca gtaaaagaac tggcaattga aaataatata cctgtatatc
    15181 aaccagtaaa ggctagagat aaagaattta tagataaaat taaatcttta aatccagatg
    15241 taatagtagt tgtagctttt ggacagatac ttccaaaaga aatattagag attcctaaac
    15301 ttggatgtat aaatgttcat gtttctttac ttccaaaata tagaggtgcg gcacctataa
    15361 attgggtaat aataaatggt gaagaaaaga ctggtgttac aactatgtat atggatgaag
    15421 ggctagatac tggagatatg atactaaaga cagaagtaaa tcttgatgaa aatataacag
    15481 caggagaact tcatgataaa atgatgaata taggcgcaga aactttaaaa gaaacattaa
    15541 gattaattga agaaggaaat gctccaagag aagtacaaaa tcatgaagaa ttttcctatg
    15601 cgccaataat gaataaatca ttaggtaaca tagatttttc aaaaagtgcc agagaaatac
    15661 acaatttagt tagaggagta aatccatggc caagtgccta tactacctat aatgatgtca
    15721 taatgaaagt ttggaaaact aaagtgttag atgaaaaaag cacaaaagat gtaggtacaa
    15781 taattgatgt aagcaaagat gggataaaag taagtactat agataatgta cttttaattg
    15841 aagaaattca gatgccgaat aaaaagagaa tgttggttgg tgaatatata aaagggaata
    15901 ctatagaaac tggtttagta ttgggttagg tgaaaagtat gacagatata aagaagtatt
    15961 taacaagtgt tgggattttg attttaatat taggaatttt gataggagtt gttaattttt
    16021 ttataataag tttaactcaa atattctcct tgatgataaa tattataata atatcactaa
    16081 tacttataat actatgttca acagcagtta cttatagagt aattaaagga aagtatgtta
    16141 actcaaatat aatgaaaata aattttaata ttgtcagtgg attatttcct attatatctt
    16201 tcattgcatc atcatttggt atgtcaaaaa gtgatattag aagaatatat ataaagttaa
    16261 ataatgaata tatatacagt aataaatata attttaatcc agaggatata ataattttaa
    16321 tacctcattg tattcaagag aatagttgta aattaaaagt tactaatgat atagataatt
    16381 gtaaagaatg tggaagatgc aacataggag aattaattaa gctaaaggaa aaaactaatg
    16441 taaaaatatt tgtagctact ggaggaaccc tagctagaaa aattataatg gataataaac
    16501 ctaaagctgt tgtagctgtt gcatgtgaaa gagatttgac atctggaata caagatatta
    16561 agaaaattcc tgttttaggt gtatttaaca aaagacctaa tggaccttgt gtaaatacta
    16621 atgtagacat tatggatatt gaaaaagcta taggcttttt aacaggaaaa aatatattag
    16681 tttgtaatta aactgttttt aagtgaagtg aatattaaga ggatgtataa taaaaatata
    16741 ttttaggaga gtgttattta tgtaccctgt atatggcggt ttttggggat ttgacccaac
    16801 aatggttgta ttaattccag ctatattact tactatatat gcacaattta aagtgagttc
    16861 aacaacaaat aagtatttaa gagtaaatac acgtcgagga tatactggag agcaaacagc
    16921 aagaagagta cttgattcaa atggtttgta tgatgtaaag atagaaatgg ttagagggca
    16981 tctaagtgac cattatgacc caagaagaaa ggctgtaagg ttgtcagaag atgtatatta
    17041 tggaacatct ataacttctg ttgcagtagc tgcacatgag tgtggtcatg ccatacaaca
    17101 tgctaaaggt tatgcacctc ttcaaataag aagtagttta gtaccagtag tgaattttgc
    17161 ttcaagtata tcttggtttt taatattttt aggatttatt atggctggtc catttttaaa
    17221 aattggtata ctattgtttt cggcttcagt gttattccaa ataataacat tgcctgtaga
    17281 atttaatgct tcaagtagag caatcgttca acttgggaat ttagggatta tagatgaaag
    17341 tgagtcaaga caaagtagaa gagtactttc agcagcagct ttaacatatg ttgcagcagc
    17401 attggtttca atacttcaat tacttagatt gttactaata gctcaaagaa gaaatgacta
    17461 aaagtaaagt gggttgttta gaaacaaccc ttttttatgt ttaataaaag ggagaaattt
    17521 atatggatgc aagagaagtt ggatttaaag tattatgtga tatagaaaaa aatgacaatt
    17581 attcaaatat tgcaataaat aagcatttta aaaatttaga aataagtgat atggatagag
    17641 gacttgcaac agagttaatt tatggagtaa tagaaaataa atattattta gattatataa
    17701 tcaataaact ttcaaaaata aaggtaaaaa aaatgtcaac ttatgttaaa atctttttaa
    17761 gaatgggaac atatcagatt ttatttttag atagtatatc agattatgca gcagttaatg
    17821 aaactgtaaa attatctaag aaatatgata aaaaatcttc tggtttcata aatgctattc
    17881 ttagaaatga aataagagct aaagagacta taatggacat aactgaggaa gatagtgtaa
    17941 aatacttatc tataaagtat tcctataact cttggattat aaaaaactgg atagataaat
    18001 ttggacaaga atttgctgaa gatttgttgg aagcaaataa tgaaaagcct agtatctata
    18061 taagaacgaa tacacttaaa ataagtagag aagaacttat tgaaaaatta agtgaaatgg
    18121 gtattgtatg tttaaaagtt cctatggtag aagaagctat taaagtcgaa aaaatgaaaa
    18181 atatagaaaa aaatgaatta tttaaggctg gtttatttac aattcaagat ataagttcta
    18241 tgatagtagg gaaagtaatt aatccaaaag aaggttcatt tgttttggat gtatgtagtg
    18301 ctcctggagg gaaatctact cacttagcta ctttaatgaa caatactggt caagtagtag
    18361 ctagagatat ttttgagcat aaactaaagc ttataaactc tactgtaaat agattggggc
    18421 ttaaaaatgt gtttgtagaa agatttgatg cttctgagat tgatgaaaat agtataagta
    18481 aatttgatta tgttttagca gatgttcctt gctctggttt tggtataata agacgtaaac
    18541 cagaaattaa gtataagaaa gaagaagagt taaaagacat cacttctata caaaagaaaa
    18601 ttttagaaaa tgcatctaaa tatgtcaaag ttggtggaac tttagtatat agtacatgta
    18661 caattcaaga tgtggagaat ataaatatag ttacttcttt tgttgaagaa aatcacaact
    18721 ttgaatttgt tccaattgat acagtaaatg tagacttaga caatcaagat aaaggatatt
    18781 taaagatata tcctaatatt catggtatag atggtttttt catagcaaaa ttaaagagaa
    18841 taaggtagtg agagaatgga aaagaaaaag atagtattaa aaaattttac tgaagatgaa
    18901 cttaaagagt ttatgaaaac tatagatgaa aagcccttta gaggaagtca aatattctct
    18961 tggatatata agggtgcaaa aacttttgat gatatgaaca atataccaaa aagtttgaga
    19021 aataaattag aagaggtttc atgtataggg catatagata tagaattaaa gttagaatct
    19081 aaggtagata atacaaaaaa atatttgttt ttattagatg atggaaatat aatagaaact
    19141 gtgatgatgg attatgatag tagagttact gtctgtgttt ctaaccaagt aggttgtagg
    19201 atgggatgta atttttgtgc atctacaatg gatggattaa ttagaaactt agagccatgg
    19261 gaaattttag accaagttat taaaattcaa gaagatactg gtaagagggt atcaaatctt
    19321 gtattgatgg ggagtggtga gccacttgat aactttgaaa atacaaaaca atttttaaaa
    19381 ataattaacg aaaaaaatgg tcttaatata gggtatagac atataactct ttcaacttgt
    19441 ggaatagtac ctaaaatgta tgagttggca gacttagaaa tagctataaa tttagcttta
    19501 tcacttcatt caccatatga tgaagaacga agaaaaatta tgcctgtagc aaatgcttat
    19561 tctattgaag aaatattgaa tgcatgtaga tattatataa aaaagacaaa tagaagggtt
    19621 acatttgaat attctcttat aaaaggagta aatgactcag aaaaagaagc aaaggcatta
    19681 gctaagctcc taaaaggtat gctatgtcat gtaaatttaa ttccaataaa taaagttgaa
    19741 gaaagagaat acgaaaaacc agataaagca tttatttata aatttaggga tagtttggag
    19801 aagaacaata tacctgccac agttaggatg tctatgggtt ctgatattag tggagcttgt
    19861 gggcaattga gaagaaaata caagtaattt gtaaggagga agtcgtatgg tttatagttg
    19921 tgcctcccat ataggaaaaa taagaaaaaa caatgaagac tattgtgagg gagaagttat
    19981 agatacagaa catggtccaa taggaatatt tgccatagct gatggaatgg gtggacataa
    20041 aaaaggtgaa gtcgccagta aattagcagt agaaaatata attgattttc taaaagaaaa
    20101 cttattacaa catgataatg taaaaataga ctatatagat gatatattaa aacaggctta
    20161 taataatgta aactcaattg tgcacaaaaa atctatggaa gatatagaat ttgaaggaat
    20221 gggaactaca ttagttacgg ctatagtgta taataatgtc ttatatgtgg caaatgttgg
    20281 agatagcaga tgttatttgt taacagatga aaaatttgat aaaataacta tagaccattc
    20341 cgtggttgaa gaacttatga tggcccatgt cattacagaa gaagaggcaa gaagacatcc
    20401 acagaggaat agaataacta gagcaattgg aacagatgat atggttgttg tagatatttt
    20461 taagaaagaa atcaaaaaaa gtgatataat acttcttgcg acagatggat taactgggtt
    20521 tattgatgat gaagatataa gagatttaat attagattat gaatatgaga gaactagtaa
    20581 tataagtgaa gaattgataa gtatggccaa tgatgtttct ggtaaagata atgtttcggt
    20641 tatagtgata aaagtataat taggacggtg atattgtggg agatacaatt ttaggaaatc
    20701 gatatgaaat catcaggaag attggtgatg gaggaatggc ctttgtatat gaggctaaag
    20761 acagattatt aaacaggact gttgcactta aagtacttag acctgaattt gtagatgatg
    20821 atgaatttct aacaaagttt aaaagagagg cagaagcagt agcaagtctt tcacatccaa
    20881 atatagtaaa tgtttatgat gttggtgaag atggaaaagt tcactacatt gtaatggagt
    20941 ttgtagatgg gaagaatcta aaagagatta tacaagatga aggtatatta gatgaatata
    21001 ctgcattaga tataacaaaa caaatagcta tggcacttag tgcagcgcac aaaaagggga
    21061 ttatacatag agatataaaa cctcataata ttctcatatc aaatgaagga agagtagtaa
    21121 aagtggctga ttttggtata gccaaagctg tttcaaattc aacaatgact aatattggta
    21181 gtataatagg ttcagtgcat tatttttcac cagagcaagc taaaggtaaa tttgtaacta
    21241 ataatgctga cctgtattct ctaggtatag ttttatatga aatgttgata ggaaaagttc
    21301 catttagggg agatagtcca atttctatag cacttcaaca cattaatgat gatatagact
    21361 ttacatcaga agaaaaagtt aggattcctc aaagtgtaag aactacaata aaaaagctta
    21421 cagaaaaatc tagtgcagat agatatcaaa ctgctgaaga attgatagaa gatatagagt
    21481 atatagaaaa aaatattgat ttagatttta taaaagaata tgatgatttt gcaactaaga
    21541 aaattgatga aaaagaaatt aataaagttg taaatccaac acttgcaaaa ccagctcctg
    21601 aaaaagtggt taagcctgtt gaagtagctg atttggatga tgatgaagat tactatgatg
    21661 atttttatga agaagatgat gatgaagatg aagaagagga agagataatg agagctaaaa
    21721 agaatcagag acctaagagt actccaagta agagaactaa gaaaaagaag aaaaaacagg
    21781 aaagcccaaa atctagaaga agattaaaag taattgcggc tgttttgata ctgatattgt
    21841 gtgctcaagt attcttagca tataagtttt tatttgctgg agggtttggc aataaatctt
    21901 tgactgttcc taatcttgta aatatgacat tagaagaagc tcaaagtgct gttgaaaaag
    21961 aaggattata cctgagtgta aaaagtgaag agtataatag tgaagttgat gaaaattgta
    22021 taatatcaca gacacctgaa ggtggaagta caaatgtcaa aaagggtgat actataaatg
    22081 ttgtcgtaag taaaggttca agtcaggcat ctgttcctaa tgtagtggga cttactttga
    22141 gtaatgcaaa acaacttatt gaagaaaata acttaaaagt gggaactgtt aagtatgaat
    22201 acagctcaat atataaagaa ggtacagttt taagtcagag tccgggtgct ggctcatcaa
    22261 gagctcagga aggtgatgag gtaaacctat atgtaagcaa aggttcagaa aaatcaaata
    22321 cacagactcc aacagtacca gataaaaaac caacaacacc agagaataat acaccaacag
    22381 aacctggttc aaactcagga aacagtggtg gaaattcagg aggctcaaat tcaggaaata
    22441 gtggtggaaa ctcaggcaat aatggaagta actcaggagg ttcaaactca ggaaatagtg
    22501 gtggaaactc aggaggctca aactcaggag ataatggagg aagttcagga ggctcaaact
    22561 caggagacaa tggaggaagt tcaggaggtt caaactcagg agacaatgga gatagttcag
    22621 gaggctcaaa ctcaggagat aatggaggaa cttcatcagg aactggcgca aacattggta
    22681 aaacagaata aatattaata aaataagagc tgtcctttta tagaaaatat tttctttaaa
    22741 gggcagtttg ttttgtataa aatactgaat tggttataat ataaggagaa aagtatttat
    22801 gaagaagaaa acagttttaa ttacaggagg agctagaggg attggtaaag ctatgtctaa
    22861 agcttttgca aaagaaggtt acaatgtatt agtaaatttt aataagtcag aaaatgaagc
    22921 taaagagttg tacactatat taaatgaaaa aaatttttct gtaaaacttt ttaaggctga
    22981 tatttcaaat agagaagatg tagaggatat ggtagattat tgtataaaag aatttggagg
    23041 attggatgta cttgtaaaca atgctggtgt aagtcaagat aagttgttta cagatataac
    23101 tgatgaagat tgggataata tgatgaatat taatttaaaa ggaagctttt attgttcaca
    23161 agttgcttta aaatacatga tatcagaaaa aaaaggaaat ataattaata tatcttcaat
    23221 ctggggtata tcaggtgcgt cttgtgaagt gcattattct ataacaaaag caggcataat
    23281 aggtatgaca aaggcattag ctaaagaagt aggaccatca aatattagag taaatagcat
    23341 agctccaggt gtcattaata ctgacatgtt atctggatat aatgaggaag atatagacgc
    23401 tcttgtggaa gaaacccctc taatgaggct aggaactcca gaagatatag caaattgtgc
    23461 tattttcttg gcatcagaca aatcaaattt tatcactggt caggtaatta gtccaaacgg
    23521 aggatttgtt atttaaaaaa aatgtggtat tatataaaaa taggaaagaa taacacgata
    23581 tactactcat aaacagtatg tgtttatata aattttataa agggaggcat ttgatgctag
    23641 aaggaaaaat tataaagggg attagtggat tttattatgt agatacttat aatggtattt
    23701 atgaatgtaa ggctagaggg atatttagaa agcagaaaat aacacctttg gttggtgata
    23761 gagtcaaaat aagcattgtt gatgaaaatg aaaaaaaggg tatcttagaa gaaatcgaca
    23821 gtagagatac agaacttata agacctccta ttgcaaatgt agataaagca ttaatagtat
    23881 tcgcaataaa aaatcctaaa ccaaacttat ctcttttaga tagatttata gttttggcag
    23941 aaaaagaaaa tttagaaact gtaataatcc ttacaaaagc agatttagat gataatgata
    24001 cattagaaac tgttaaaaat atatatgaac ttagtggcta taaagtcatt cctgtaagca
    24061 atattactaa gttaaatata gataaagtaa aagaagaatt aaaagaaaat gtagtagtgt
    24121 ttgcaggacc atctggagtt ggaaaatcaa gcttattaaa tgaaatagat gaaaatttta
    24181 aacttcaaac aggagttgta agtgataaaa taaaaagggg aaaacatact actcgtcacg
    24241 ctgaactttt aaaattagaa tttggtggaa tggttgcaga tacaccaggt tttagttccc
    24301 ttgcccttga agatatagag gaagttgaac ttaaagatta ttttatagaa tttgataaat
    24361 ttaatgattg taagtttggt tcaaagtgta ttcatgaaaa tgaacctaat tgtgctataa
    24421 aagaagctgt tacaaatgga gaaatatcta aagaaagata tgatagttat atacagctgc
    24481 tacatgaaat aagacaaaat aatagtagga ggtattagaa acatgattaa attagcacca
    24541 tcaatattat cagcagattt tgcaaaatta ttagaagatg taagaaaagt agaaagtgca
    24601 ggatgtgaat atcttcatat cgatgtaatg gatggacact ttgtaccaaa cattacatta
    24661 ggaccacttg tagtcaaaag tttaaagaaa gaaaatataa atatggtatt tgatgctcat
    24721 cttatgatag aaaatccaga ccagtatatt gaagaatttg taaaagcagg atgtgatata
    24781 ataactgttc accaggaggc ttgtgttcat ctacatagaa ctatacaaaa tataaaatca
    24841 catggaataa aagctggtgt agtacttaat ccagctacac cagtagatac gattaaacat
    24901 gtactacctg atttagatat ggtattatta atgtctgtta accctggatt tggaggacaa
    24961 tcatttattc cttgtgtttt agataagatt aaagagttaa aagctattat agatagtcaa
    25021 ggattaaaca ttgatataga agttgatggt ggtataagcc ctaaaaacgt agccgaagtt
    25081 gtacaagcag gagctaatgt aatagtagca ggttctgcaa tatttggaag tgatgacatt
    25141 caagaaacag ttaatttatt tagaaagaat gcttctcttg aagaattagt ttaaatttaa
    25201 taatgaaaat ctgtattgtt ttaaatggcg aaattgaaga ttacgaagtt acaagagata
    25261 ttataattaa ggaatgttat gactgcataa tatgtgcaga tggaggggca aatcacactt
    25321 ataaaatgga aataatgcca gattatatat taggagattt agattcagta gaagaagaaa
    25381 agataaactt ctataaaaat aaaggtgtta aatttgaaaa atttccatct aaaaaagatg
    25441 agactgatac agagctttgt ctttttttag ctaagacact taaagcaaat catattgatt
    25501 tttttggtgc tttaggggga aggattgacc acactcttgc aaatataaag ctattatatt
    25561 atttaaaaga agatggtata tattctagga tactttctga taaagaagag atgtatatag
    25621 ttgaaaatga ggaaatttca ttgtatggaa acccagggga cactatttct gtaatagcta
    25681 taaatggtga tgctaagggt gtaacactta ctggcttaga ataccctctc gataattatt
    25741 atatgaaata ctctgtacct attggaatat caaatgttat gttgagtaat tcttgtaaga
    25801 ttaaagtaga gcaaggctgt gtacttgtag ttagaaattt ataaaatttg attttgacaa
    25861 ttggttttat attgtagagc agatacaatc aagtaaaata tatttatgat tgtatctgct
    25921 ttttagtata taattataaa tatataataa actttgacat aagggggatt ttttgtggta
    25981 gatagtatta tttttgattt agatggaaca ttgtgggatt caactgaaga agtatgcaaa
    26041 gtctggcagg atgttttaag tgagcataag gaaatagaat taagtgtcac aaaagattta
    26101 tttagaagtc ttatggggct ttcttttgag gaaatagcaa atcgtttatt tccaaattta
    26161 agtgaagaag aaagaatgaa tttattgaat gaatgttctt tgaaagaatg tgactattta
    26221 tctgaaaatg gagctaaatt atttgatgat atagaagata ctcttaaatt actatctaaa
    26281 aaatataaat tatttatagt aagtaattgt caagctggat atatagaatc ttttttaaaa
    26341 gcacataaac tagaacagta ttttatagat tttgaatgtc ctggtaatac tggtttgcat
    26401 aaaggagaaa ataataaact tataattgaa agaaataaat taataaatcc aatctatgtt
    26461 ggtgatacgc aaggtgatgc aaatagtgct aagtttgtag gtataccttt tatatatgcc
    26521 aaatatgggt ttgggaatgt agatgtatat gattatttta tagattcatt taaagatttg
    26581 ttagaacatg atatattaaa ataagatgag tttaaaaatt atattaaaat aataaaaaag
    26641 ttatgggggg atttaaaaat ggaattacaa gatactattt ttaaaagaca aagtgtaaga
    26701 aagtttaaaa atcaagatgt atcagatgaa gatattttaa aaatgataaa agcagcaggt
    26761 gcagcaccat caggcaagaa tattcaaaac tggcattttg ttgttataaa acgccgtgat
    26821 ttaatggaaa agatagcaga tgtgataact aaaaagcaac aagaaatact tgtagaaatg
    26881 gataaagtat cagtggataa ggctaataga tttagaaaat ttgttaaaaa ttttacacta
    26941 ttttacttaa aagctccagt tttagtatta gtttttacaa aggtatataa tccatcagga
    27001 tattatgaat tagagcttat agatgcacct aaggagacta tagataaatt atttataaga
    27061 aatccaggta tgcagagtct aggtgctgca attgaaaact ttacactatc agcaattgaa
    27121 cttggatatg gttcttgttg gttgacaagt caaaactatg cagcagatga gatagaagct
    27181 gttttagaag cagaaactgg ttttgaaaag ggagagtatt ttttaggtgc aatgttagct
    27241 cttggagtgc cagaggacaa tttgaagagt ccatctaaaa aaccagtaga agaaatatgt
    27301 acatttataa aataaaagtc aaggacattt taaaatcgaa gtaaattaaa aacaaaataa
    27361 attaaaaata aatatttaaa aaattaaaaa gtaggtttta ttgatattaa ttttatattt
    27421 caaatcattg atttaattaa tacaataaga actacttttt ttgtatatta attttaaata
    27481 tatttaaatc tttagaaaat ctttagaaaa gtatatgtaa tatcttaagt ttttaatttt
    27541 aatattaagt atataaaaca aaatgaaaaa atattaaatt taaactagaa ggaggtttct
    27601 aagatggaca ttaaatacaa ataaccagaa caaaagatat aaatatatat ataaatggaa
    27661 aaacttctat catattgtat aatcatatat gtaaagaaaa tttataaatt aatataaagg
    27721 agattagaat gaattcatat aatattttgg tggtagaaga tgaaaaggag atagcagatg
    27781 ctatagaaat atatctatta aatcaaggat ataatgtttt taagggatac aatggattag
    27841 aaggtcttaa ggttatagaa aaccaagaaa tacatttagc tatagttgat ataatgatgc
    27901 ctaaaatgga tggtataaca cttacaatga agcttagaga aaactataat tttccagtaa
    27961 taatgctatc tgcaaaatca gaggaagttg acaaaataat ggggcttaat ataggagcag
    28021 acgattatgt aacaaaacct tttaagccat tagaactatt ggctagagtt aattcacaac
    28081 ttagaaggta cactaagtat ctaaacatgg ttggaaataa agagcaaaag gtagaaagtg
    28141 acgatagtgt gtttgcaata ggcggattag aattaaatga aaatacaaaa gaagttagta
    28201 ttgatggaaa gtatataaaa acaactccta tagaatttaa aatactaagt ttacttatga
    28261 gaaatgcagg aagagttttt tctgctgatg aaatatatga aagagtttgg aatgagaatg
    28321 ctgtaaatac agatacagtt atggtacatg tgaggaatat aagggaaaag atagaaattg
    28381 acccaaaaaa tcctaaatat ttaaaggtgg tgtggggtgt tggatacaaa attgaaaaaa
    28441 tttaaagata aatatatagt tactattata gtttttatac ttatgttatc agcatcatta
    28501 ggtatgatta gtcaatattc tactatacaa gcaagtgcta aaggtggagc agagaatcca
    28561 tttgaacagg aaagctttgt agatagtata tataaaggaa gttatgtttt atatcataat
    28621 atgaaggaag aacaagaagg taagatgata caaccatcaa aactatttat caatgaagaa
    28681 actatgaact atataaaaaa tgtaagtaaa gaaaaagata cttatgatgg ttcagaaact
    28741 tactatacag atgatagtat taatgcagat tttaatgaaa actttgaaaa ttgggagcat
    28801 ttcattaaag cgtcaggaaa gaatttaaag tactatttag ttgataaaga aagcaatttt
    28861 gaatttttta atgataataa agaattagga gtacttgata caacaaaaaa tgatgcttca
    28921 aaagaaaatt ctgatgaaaa tcagtcaaaa aatacagaaa tgaatgatga ggaaagacaa
    28981 aagcagatta cagatataaa agaaaactat agattctacg ttgtaatgaa ttttgataaa
    29041 gatggaaaag taaatattgt ggattcttat ggagtaaatc aaaaaattat taatcaaatg
    29101 ttgttatcta aagcaagaga agatttaatg gatacaagtt taggaggaaa ttcaatttca
    29161 tataagttat ctccaataaa aaatataaca ttagtatatg ctgtacctaa agtaataagt
    29221 aaaggtgata gtgtagagta tggttatgga aatacttatt ttgatgatgg tataatttca
    29281 tatataagca atgtagaaaa taattcttat tataagattt ctggaatgat tttaaaaatt
    29341 atattagcta tagttgttat tgtagcttta gcattcccat atagaaaatc taaagagttg
    29401 ctaggatttg atacattatc aagaataccg ttagagatac tctttattgc tcttgctatt
    29461 atacaggggc ttgtagattt atatcctact gttataataa gtaatacctt gagtgggaat
    29521 tatgtagagt accttataaa caatgacata agtgctaaaa tggctagtat attggtaagt
    29581 ttaatgaatt taacttattg gtttgtaata ttctcaataa tatttgtatt tataatactt
    29641 ttaaaacata ttttaaatgt tggaataaga gagtatttta caaaacatac tgtgacagga
    29701 atgttttttg tatggctaaa aaaagcagga aaaacagtta ttaatcaaat tagaacaata
    29761 aatctaaaag aaaagccaaa taaaactata gttacaattt tgggaataaa tttattgatt
    29821 atagttataa tgtgtagtat gtggttcttt ggaataatac tcgcattaat atattcagta
    29881 gtattattta aaatactgtc agattactct aaaaagacaa tatatgaata taatcaactt
    29941 ttagatgtta caaagaaaat ttcagatgga aacttagatg taaatatgga aaaagattta
    30001 ggatttttta atcctataaa agacgaatta ggaaatattc aaactggatt taaaaaagct
    30061 gttgacgaag aggttaagag tcaaaagatg aaaacagagc ttatatcaaa tgtatcacat
    30121 gacttaaaaa cacctctaac atctataatc acttatatag atttattaaa agatgaaagt
    30181 ataacagatg aaaatcgtaa gttgtatatt gatacattag acagaaagtc acaaagattg
    30241 caacatctaa tagaagattt gtttgaagta agcaaggcaa atagtggaga tgtttatttg
    30301 aatatagtaa atgtggatat tgtatctcta atgaagcaga cacttttaga attagatgac
    30361 aaacttgcag attcatctct aatagtaaag aataactttt ctaatgaaaa aataatatta
    30421 ccattagata gtcagcgtac atttagagta tttgaaaatc ttataataaa tataagcaaa
    30481 tatgcaatgc caaattcaag agtgtatatt gatattttag aaacagataa taaagtaaat
    30541 attatgctta aaaatatgtc tgcatctgag attgatttta gtgtagatga tataatggag
    30601 agatttgtaa gaggagataa atcacgtaac acagaaggtt ctggtcttgg tttagcgata
    30661 gcaaaaagtt ttatagaatt acagggtggt aagatgaata taagtgtgga tggtgattta
    30721 tttaaagtta caattacttt taacaaaaat tagattagac ttctttaata attataaagt
    30781 ctataggata aaagagtctg gaaatattta tgtgtattct ttaaataaaa atttataggt
    30841 attgttttaa aataatttgt aagcattatt tcaaaacagc ttataaatgt tattttaaaa
    30901 cagaatgttg atttatttaa aaaaggtgaa tcctaatata caaggttcac ctttttattt
    30961 tacaaaatgt tatttagtgt tacagagctt ataaatagca taatatctgg ctttactatt
    31021 aacatggtac tagcaattta ttttgaaatc ttgtataagc tattttatat tatttaatta
    31081 ctattgtttg tactttacaa tgtgataaag aatttacctc tacagtttta gtatttactt
    31141 taagcttgct agtattatca tagatttcgt cgagcattgc actataagca tcattgacat
    31201 ttttattgat gttaagactt cccttagcat cctcattttt cataccattg aagattctaa
    31261 ctacaattcc atctcctttt tcttctttct ttattgcact tactgtgaaa tttgaattat
    31321 ttacattcat caaactaaat tcattttcat atatttgttt ttcgtcattg aatgcaaata
    31381 taagtctacc atttaaaaaa tcagcatatt catatatttg tataggtgtt aagaatctct
    31441 tagctgtatt agctacattt gcttcatcaa atttattgtt atatatgtaa agaccaaagt
    31501 caaagtttaa ctctttaagt aattgtgcat ctggtgttgc tattattttt tctccagaag
    31561 ctcttcctgg tctataaagt aaattttctc ttcccatata tccaaatgac ctgaatagtg
    31621 ttaatgctat tgtatctaaa ttatcaccaa ctatttgata ttctcttaca caaccagtta
    31681 ttaatgctat tcctctttgt ccatcctcta aagtaacaaa actttgcatt ggttcgatag
    31741 ttataggttt ttcttgccat gagtaattgt ctcttttcca caatgcaagg tctttttcta
    31801 atactgttgg tctttgtatt attccaaatt gttgatctgc tatagaaaac ttagatgcta
    31861 tttctgtatt aaataaaact cttactctat gagatagtgc ttggttattt tttatattaa
    31921 cattaaactt aattatttgt tctttaggtt ctaaggtgat tttcattgtt actggcattt
    31981 tcacagaaac tttacctata gccctttctt ccagtgaagc tggtatggtc aatgaatatt
    32041 taagtatcat ttcttcttga atgtttgatt ttagcacttc tactgaagat acagaatcta
    32101 aagatgaaac ataaatatct tttcttggag gagaatagtt gtatgaatct ccatcatctc
    32161 cattgtcttc aattacagct tggtttttat aagtcttatt agattcttta tctaatattt
    32221 ctaatgaacc atttttattg gctgttattt tgtagtattt gttttctatt tccttgcaat
    32281 tacttgtttc tatttcacat ttatttttag tatccaattc aaaaactagt tgagtatatc
    32341 ccattggtgg tatatctttt actgaaagtg caatttttgc tctatataca gttttgggta
    32401 tatatatttt tttacttggg tttaatctta ttgtttgagt taatatataa tttgtaatat
    32461 cttctttttc ttttattata taattaagaa tttttccatt tttattcttt atcacaaaat
    32521 cttgacctgg aatataagta tcaaattcta caacttcatt tctgacttct gggaatccat
    32581 tgaatactgt taatgttatt tcttcattat tatttttgat ttgagtactt ataagtctca
    32641 tatgcaaatc taataaattt atactcaaat ctctggcttg tttgtatctt gtgtatacat
    32701 cctcatttgt tgtgtcacta ttacaagaac ctatgctgtc atgagctgca ttttcaaaca
    32761 taagtttcca tatatctttt ataactaggt gagggtattc atttccaagt gaataactta
    32821 atgttaataa cggttcaagt acatttgtaa tataattttc taatttgtta ttcattattt
    32881 taaggtctga ccttgaggag aatatggatt tgtgtattct catatgttta gcatttaaaa
    32941 attcaccttt aagctctgta aattcatttc tttcatttct tactgaatct atatagtttt
    33001 ctatatcact tatttcgtat tcattttcat tatctatttc attagctttt tttaatatat
    33061 caggaaggtt ttttcttatt ggtgcttggt caaatccatt tggaaaatat acgttattag
    33121 tagaagcttt aaccttaagt tttacgatta tatcttttaa atattctttt aaatctgaat
    33181 catcttctgg tatattacct ccatagtaat aaccaaatgg tatttgaact gctaatactt
    33241 ttgaaccatc agaacctttc catataaact ctgttgtatc taccatatca tcagaaactc
    33301 cacgccaaaa taatgaacta tctattccaa aacctctgta tatttgtggc atttgagctg
    33361 attgcccaaa agaatctggt acatatccaa ccctcatagg ttcaccaaat tcattgcatc
    33421 tatctattcc atagtaaagg tttctaatta tagattctcc tgatataacc aattggtctg
    33481 tttgagtata ccaaggtcca ataactaatc ttcttctttg aactaaatct cttattctat
    33541 atttatcctg aggtctccat tttaaataat catctaagag agaagcttgt gcatccatag
    33601 taaagtattt aaagtcttct ttttcttcca atatgtctaa tatatcttga aaatctttca
    33661 ttaaatatat ttttgacctt gatgttgtaa aataccattc tctatcccaa tgactgtgtg
    33721 gaactacatg tacttttgtc tttttcataa aaatcctccc aaaatttaat tgagaattga
    33781 gagtacactc aattctcaat tatctaaaat taagttttta atttacatta tatctaactc
    33841 tatttcatca aattctgtat tttccgtagt ttcatcttca ttgaagtcta ctaaagttgt
    33901 tgataatatt gctattacta aagctccaaa tattgcacct actaagtaag cccatccaga
    33961 acctattgat ataaatccat ataatccacc aactggaggc attatagcat gtacacctaa
    34021 caaagctgat aatcctacac ccaaagcgca tcctatcata ttaacaggaa ctaattttaa
    34081 tggatttgtt aaagtgaaag gaattgcacc ttctgttatt ccaattatac ccataactat
    34141 attgcctttt cctgtttcag ctaatgcatt ggaaaatttt gattttctta tgaatgtagc
    34201 taaaccatat cctagtggag gtataactat tgcgcagttt accaatatcg ctggtagata
    34261 gattccctct aacaataatg catttcctgc catccaagct gctttattta ctggtccacc
    34321 taaatcgaat cctatcattg cgcctaaaat taaagccaat accaccgaat ttgttccatt
    34381 ttgacacatt tcagctaccc aagcatttaa tgaagtattt atgtttccta aaggtcctgc
    34441 taatacaaca ctcattaaaa aaccagttaa tccaactgtt ataagtggca ttattataag
    34501 tggcatcatt cctgatgctg acccagatat tttaattttt ttctttaaaa acttacaaac
    34561 atacccagca aagaaacctg ctattactgc tcctaagaat cctgcattag tattacttgc
    34621 tatgagccca ccaataaaac ctgcacccat agctggtttc tcacctattg aaaatgctat
    34681 aaatcctgct aataccgtat ttaatagacc tatgccagtc caaccaactt gttccattaa
    34741 gtaaagaata tgataaaaac cagatacatt tttataagca tctaaacttg ttatacccac
    34801 tgctaaagct gtaagctttg ggatagctac aactaaagat gagcctatta caagtggcaa
    34861 catatatgag atacctgtca ttaagtgtcc cttaagttca cttaaaagag atttattttt
    34921 tttactcatt tttaatcctc ctatataagt ttgttatatt ttttgataat atgttataat
    34981 tacattagac aattttttaa tttttgattt ttctcattct atattagagt gagatttttt
    35041 tattaagaaa tagcttctat acactttgtt aagacagctt ctggtttttt taacgctata
    35101 cctattttga cttttatcac ttttttacca tcaaatcttt ccattccaga tatagtttgg
    35161 tcagatgcta taagtataaa gtccgcatct tgtgcttctt cttttgttat agtatttact
    35221 cgtcccatag caccttgttg ttctactttg atttcatgac ccatttttga tgcagcttgt
    35281 tctaaagctt ttgctgccat aggtgtgtgt gctaatcctg ctatacatga tgttatagct
    35341 actattttca taattattcc tccttcattt tattagttat atattttact aaatgacttg
    35401 catcactagc atttttaact tcacttgtaa aatcatcctc cattaaacat gtggctaatt
    35461 tagatagagt tttcaaatgt atatttcctt catttttatg tggggctaac aaactaaata
    35521 catatctaac cttactatca tctaaagttt tccattctaa ctcgttagtt gttttaatat
    35581 agagtatgga agcttccttt acatttacac tctttgtatg aggtatcgca aatccatctt
    35641 ttattcctgt tggaaattca ttttctcttt ttagaaggtc ttttaaaaga gcctctttat
    35701 tagttgtaat acctagtata taagcactat ctgcaataaa atttaatact tcttctttgc
    35761 tttttaagtc tttatctata aatatatatt tttcttgtag taccatatat ttttccactc
    35821 cattcataat gtcttaactt atatttatat tgtaatcatt atcctaatta aattaaatat
    35881 aactaatttc cacttcgaca tggaaattta tattatgata ataactaatt tccatataga
    35941 agtggaaata aattattata atacaatttt attagagtaa ttgtattata tgagtgtaaa
    36001 tagtataatt tagaagaaat tctataaggg gggatattta tgcacaagag attgctcacg
    36061 ttgtttaaat tattaaatga aagtgatgat aaaattactt gtaaaacttt aagtaatcat
    36121 ttaaaagtga gtgagagaac tataagaaat gatattactt ctataaatgg aactttagag
    36181 aaaaatggtg ctattattaa aataaaaaaa ggagaaggat attatataga tattcttaat
    36241 ttagcattat accaacagta tctagcatta atatctgatg atattatgga ttcaagtgaa
    36301 ataccagatt ctcctataga aagaaatcaa tatattttaa aatatattct ctataacaat
    36361 acatatataa aactagaaga tttagctaat agcttgtatg tgagtaaatt tacaatacta
    36421 aatgacataa aaagaataaa gcctattttg tcaaagtata atttaatatt agtttctaag
    36481 ccatattatg gagttaaagt tgaaggtaag gaaatagata ttcgaagatg tatttctaat
    36541 aatatgataa ataggaattt tgaaaactat ataattggaa ttacagatag agaaatagaa
    36601 ttatttaata atgtagattt aatagagctt caaagggtag tgttaagtga aattaataaa
    36661 tttaatatca atttcctaga ttttaatcta aaaaacttta ttatccattt agctattact
    36721 gtaagtagaa tacttgatgg ttactgctta gataatgttt tagatgttgt tttaacagat
    36781 tttcaatcga atacaactgt tgaaaatata tttaattata ttgagagtaa atatactata
    36841 attatttcaa aggcagacag agtttatcta tataatcatt ttataactaa aagttctctt
    36901 ttggataacg tttccaatag ggtagatact aaaattatag agtatgttga agaaatttta
    36961 gaagtaatca acaatcaata tacttttgac cttagaaatg atagtgtatt atttgatgat
    37021 ttagtactgc actttaaatc aattctcaat tctaaatctt ataatttaaa taaggtgaat
    37081 ccccttataa atacaataaa gagtaattat cctttagcat ttgaaataac tttaaatgct
    37141 atagaaaaag tttttaaaaa tagtatttac tctttaacag aagatgaaat tggatatgta
    37201 tccctgcata taggtgctgg aatagagaga ttttttcaaa gtaatattaa gtgtaaaaac
    37261 gtagtattag tatgtggttc agggtatggt tcaagtaggt tattagaggt tcaattaaac
    37321 aaagtttttc atgataaaat aaatatactt caatgtctat catttaatca atttttagct
    37381 agtgaattgt cagatgtaga tataataata tcgacaattc ctttaaatca tgatagtatt
    37441 cctattgtat tagtggattt aaaactatta aaaaaagata tagagaatat atctaagtca
    37501 atcactaata attcccatat ttatagtaat cttttggaca atttctttga taaaaattta
    37561 tttattgtta atcctaaaat caaagataaa gatgagctta taaagttgat gtgcaacaaa
    37621 ttaactcaaa gtgaaattgt atttccatca tttgctgaat ctgtatttta cagagaaagt
    37681 ttatcttcta ccaatataga tgatttttta gctatacctc atcctatgga attaagctct
    37741 ataagaacta agatttgtat ttccatattg aatgaaccaa tatattggag tgaaaattct
    37801 actgttaaat taatcatgat gttggctata aataaagatg attatataaa aataaactcc
    37861 atttatgata tccttttaaa gataattcat gacaatgata ttagagatag tatatctaat
    37921 tgtaatgatt ttgataattt tctttccata atcaagtcta tagtatagat ttttatatta
    37981 cataagtttt aaaaacttta ataaaatatt ttttgttttt agcataaata gtataagtaa
    38041 gttttgtata atttgttatt attttgtatt gattataatt attatacaat aaagattctg
    38101 tctcaaaata gagagagaaa cctgtttttc attgataaaa tgataaaaat atatctgatt
    38161 tcatacaaaa aagagtgtct catgaactaa aaagttcatt ttgagacacc acctttatta
    38221 ttttatatta tttatctctt gtatatatta ctatagcatc ccttaaaaac ttagctaatc
    38281 caggttgttc tctatcataa tatgatgtaa aacgttcatc atatacatac atctgtgcta
    38341 gagaggaatg agcttcttta gagtatgtgt tccaagtgta acacaaccat ttatgatgta
    38401 attttgcaac ttcctgagcc agttcactag aggcatcacc agttttaaaa gcttttttaa
    38461 gtttactaat tatttcgata tttaggtttt gccaattttc ataatcttgc ttagacatat
    38521 ttttaagttt tttatttgat gtatctataa tatctttacc atatttctct ctaatttcag
    38581 ttccataatt tttttcattt tcatcaatca tcttttcttt aaaaccttca aatttttcta
    38641 tatctgtcat agtgtatttt ccctccttca gagctatagt tttagttaca ttttctatta
    38701 gtaaatcaat ttgctttctt ttggctagta atttattatg gtgttctttt aacgcactta
    38761 aactatcgaa gtttggtgaa tttataatgt tttttatatt ttctaagtta attcctaatt
    38821 ctctataaaa aagtatttgt tgaagtttat taacttcatt ttgaccatat atacgataac
    38881 ctgaagaatt tattttaagt ggcttaagaa gacctatttc atcataatat ctaagtgttc
    38941 tagtacttat accagctagt ttacttaatt tttgaactgt atattccata agtagtacct
    39001 cctataaatt aaatatacac ttttacgcaa cgtaaatgtc aatacattaa aatataaaaa
    39061 tttatatctt ttaataaaaa tataaaaaaa tatctttact ggatatttta cacacaactg
    39121 tcaatactca ctagtgaaaa ttaaaaaata aaatttatag actatcttta ctaaaaaata
    39181 gaaggtctat agtctaggag gaactgtatg aatttaaaaa gaagcaatga aaaacgagaa
    39241 gagtacagaa gaatgtattc agataaagaa agttttttaa gtttgattca aaattttaca
    39301 agtgtctcaa tagcaaaaga attaactctt aaaaatatag agttagaaac atcttttata
    39361 tgtgaatata aaggaaaaga agttgatata atttataagg tattttctaa aagcggcaaa
    39421 gtatcacatt atatagtgtt agaatttcaa acagaaatgg atactgaaat tgtcccaaga
    39481 ttgaaatcgt atagagaaca aatttggaaa agttttatta tgaaaaaaag ccttgaagaa
    39541 atagaagata aaaattttaa acttcctaaa gttataccag ttgttttata tagtggacct
    39601 gaaaggttaa gtagaaaaaa aggaattttg gatattgtag aatctatatc ggagttcagt
    39661 aataattcta gtatgaaaaa ttaaaattac ataatgtgtt tattggtcta aaatggaaaa
    39721 ctgtcgcata aacttgaata tgaaaatatt tatagataca ggttctatgt ggaggtgttc
    39781 catgagaaat aacaagtcta aggtattgct aggaatactt tgtctagcaa caggaatggc
    39841 tgtaattctg tcaatgttgc ttcctggctg gatttggtca gcacttaccg cattaatact
    39901 tattggatgt ggagcattat tatttttttg ttaaaatagt tttaactata aagtgtgggg
    39961 tgagtattga tgaaagtagt aacaataaaa ttaccaaaat ggatttcaag tataatccta
    40021 aaatttatga gaaagagtaa aaatgattaa attaaaaagc ctacttacgg aagtaggctt
    40081 ttaaacgtgg ttactaagct ctttcaattt taccagaacg taaacatcta gtacaaactt
    40141 ttactctctt aggagctcca tctataatcg ctcttacgct tcttaagtta gctgaccatg
    40201 ttcttttatt atgtttattt gagtgtgata cttggtttcc agaaacctta cctttaccac
    40261 atacgctaca tacttttgcc atctacgcac acctccttaa aatgataact atttaaagac
    40321 taaaaacata tttatattat cataaataac aaaaatttgc aatagaaata tatatttgcc
    40381 ttacacatat tgaagaattt cttattatca tataaaatta tatatataat tttatataaa
    40441 gtaaatatat ttggaaaata attattattt ttctttgaat atatatacta tagaagaaat
    40501 tttatccaaa aacttttcta ggtttaaatt ataccatatt tatagtatga tatgattata
    40561 attttatata ataaataagt aaaaatagta aaaaataaat taagaaatgt ttttaataaa
    40621 aataagctta agggggtcaa ccatgagtgc aaaggtaacg aatcaatatg gaaatataga
    40681 aatagataat caagtaatag ctcaagtcgt atatagagct gcaatggaaa gttatggctt
    40741 agtaggttta gcatataagt ctaaaggaat agtagagcta ttaaaaggcg agaacgcaac
    40801 taaaggtgta agagttgagg aagtagaaga agatgccata gcaatcgaac tttatgttat
    40861 aatacaatat ggtacaaata tatctactgt tgccaataat ataatagata gagtaaaata
    40921 tgtagttgaa aaaatgactg gcgtaagagt tactagaatt gatattaatg tacaaggaat
    40981 aagagttaag taatttcata ggaggaaaca aatgattcaa tatatagatg gtaaaaggtt
    41041 aagggagatg tttatttcag gtgcaaacaa tctccaaaac aataaagagt tagttgacaa
    41101 gttaaatgta ttccctgtac cagatggaga tacaggaact aatatgtcat taacaatatc
    41161 ttatgcctta aaagaattag caaaagttga aaatgataat atatcagata tcggaaaagc
    41221 attatctaaa ggttctttaa tgggagctag aggaaactca ggagttatac tttcacaaat
    41281 aatcagaggt atagctaaat ctatagaagg aaaaagtaaa ttatcaacag aagatttagc
    41341 aaaagctttt aaaaatggtt cagacacagc atataaagct gtaataaaac caattgaagg
    41401 aactatactt actgtagtta gagaaagtgg agagtttgca ataaaaactg cgaaaaaaga
    41461 gaaagatgta gtaaagtttt taagtatgct tgtgaaggaa tcaaattctt cattagaaag
    41521 aactccagac cttctaaaga atctaaaaga agctggtgtg gttgactctg gtggaaaggg
    41581 tcttgtactt atatatgaag gaatgttagc ttctataaaa ggcgataaca tagaaataaa
    41641 aaatgttgac ctagatacta atatttcaac aagtatggat tttgcaaaga gtactactag
    41701 cacagatgat ataaaatatt gctattgtac agaatttatt ttagaaagtt ctaaggtaga
    41761 agatactaaa ataagagaca taatgatggc ttatggtgat agcctagcag tagttggaga
    41821 tgatggagtc ataaaggtac atgtacacac taatgaccca ggaaatgtac ttcaagaagc
    41881 tctaaagtac ggtcaattat taactataaa aatagaaaat atgaagttac aacatgaaaa
    41941 tacattactg gatgtagaag aaaagaaaga aaatgatagt gaacctttag aagaagaaaa
    42001 agagtttggg tttatagcta cttctatggg tgaaggtttg gcaaatatat ttaaagattt
    42061 cggagttgac catataatag aaggtggtca aactatgaat ccaagtactg aagattttat
    42121 gaatgctata aagcatataa atgctaaaaa tatatttatt ttcccaaata acagcaatat
    42181 aataatggct gctaatcagg caaaagaatt gagtgataaa aatataatag ttatacctac
    42241 aaaaaatacg cctcaaggat ttgctgcatt agtaactttt aatggagaat taagcgaaga
    42301 tgaaaataaa gaagctatga tgaatgcttt aaactcagtt aaatcaggtc aagtaacttt
    42361 tgctgttagg gatacagtga tgaatgaaat tgatgttaaa gaaggtaata taattggaat
    42421 tgcagaagga aatttattat cagcaggaga ttatgtggat gaagtaacat caaaccttat
    42481 tgaaaagttg gttgatgaag atactgctat aataacatta ttctttggtg aagatgttac
    42541 agaatctcaa gcaaatgaac tacgtacttc tttagaagaa aagtttgaag atgtagatgt
    42601 agagttatat tatggaggac aacctcttta ttattactta atttcagttg aataatgatt
    42661 ataagaacct gtatgaccaa gtagctttta taaaattggt tgtacaggat ttttgtgtag
    42721 taggtgatat atttgttgga tttatataaa gatgttcaat atgttaaggg aataggacct
    42781 aaaaaagcag ataaattaaa taaactgggt atatttacac taaaagacct attgtattat
    42841 tttccaagac aatttgaaga tagaaataat ctaaagaaaa tagcacaatt agaagatggt
    42901 gagaaagtta cgataaaagc agtaatatca agtataaata catttagccc aaaagaaggt
    42961 atgactttaa caaagattga tgtaaaagat gagacaggct cggctaaatt agtgtttttt
    43021 aataagagtt atataaaaaa tacttttcgt ccaggagatt caatattagt ttttgggaag
    43081 gttaagaaaa aatttaataa cttagaactt acatcatgtg aattagaata tcttactaat
    43141 tcacctaaga atacatgtag atttatgcct gtgtaccagc ttacatacgg tgttacaaat
    43201 aaagaaatta tgagtataat tagaacagta cttgaagata aagaattaat tatacaagaa
    43261 tatatgccac aaagaattat agaaaaatat aggctatgta gtatagattt tgcagttaga
    43321 aacatacatt caccaagtag taaggaatca ttaaaaatag ctttatatag aattgtattt
    43381 gaagaattac ttatactaca actagggttg tttgtattta aaagtggcag aaataaagaa
    43441 gatggaataa agtttgaaac aagtaaagac ttaaaaaaaa taataagtgc tttaccattt
    43501 aaactgacta aagctcaaaa cagggcatta gatgaaatta tacaagatat gaatttagag
    43561 aaaataatga atagattggt acaaggtgat gtagggagtg gtaaaacagt agtagctctc
    43621 ttagcacttg caaattgtgt tttaaatggt tatcagggcg ctttgatggc acctacagag
    43681 atattagcag ggcaacatta tatttcactt actgagtctc taaaagattt tggaataaat
    43741 gtaggtctat taataggtag tcttacaaaa aaacaaaagg atacagtatt ggaacaaata
    43801 aagaataatg agattgatat attaataggt acacatgcac taattgaaga taaggttgaa
    43861 tttaataata ttggtttagt tataacagat gaacaacata gatttggtgt tatgcaaagg
    43921 agcaaacttt cattgaaagg agcaaatcct gatatattag taatgacagc aacaccaata
    43981 ccaagaactt tagcacttat actctatgga gatttagata tttctattat agatgaactt
    44041 cctccaggaa gacagccaat agaaacaatt gctattgaaa aaagtaagcg agatagagca
    44101 tataataatc ttgtaagaag agaggttgaa tcaggaagac aagtgtacat tgtatgtccc
    44161 ttggtagaag aaagtgaagc catagaagcc aaatcagcag ttgaacttgt tgaggagtta
    44221 agagcggaat attttcacga cttaaggctt gggttgcttc atggtaaaat gaagtcaagt
    44281 gaaaaagatg aagtaatgag actttttaaa gataaagaaa tagatatttt agtttcaaca
    44341 acagtaatag aagttggtgt caatgtgcca aatgcaacat taatgataat agaaaatgca
    44401 gaaagatttg gacttgcaca attacatcag cttagagggc gagttggaag aggtagtcat
    44461 aaatcgtatt gtgtactaat ttatgattct aaaacagatg tatgtagaca aagaatggct
    44521 ataatggaag agaccaatga tggttttaag atttcagaga aggatttaga aataagagga
    44581 cctggggaat tttttgggac aaggcagcat ggtcttccag aacttaaggt agcaaactta
    44641 tttaagcata taaaaatact gaagttagca cagcaagaag ctcgatatat attgggtgaa
    44701 gataataatc tacaattaaa agaaaacatg gcactcaaaa aagaaattat agataaattt
    44761 aaagatacat tgaaagaaat ttcattaaat taattttaaa ttgtgttaaa atattactaa
    44821 tgtaataatg tgctgaaggg agattgtcat attgagagta atttcaggaa aagcgagagg
    44881 attaaaacta aatactccaa aaaatgaaga tgtaaggcca actacagata gagtaaaaga
    44941 gtctctattt aatatgataa attcatatat aatggaaagt gaagttctgg atttatttgc
    45001 tgggactggt tctttaggaa tagagtgctt atctaggggt gccaagtcat gtacttttgt
    45061 agatattagt aaggaaagca tagatattgt taagtccaat ataaaaaagg caagagttga
    45121 aagtgaaagt attattttaa accttgattt taagactgca atagataaac ttaaattaca
    45181 aaatagtaaa tttgacataa tttttatgga ccctccgtat tataaaaata tgtttataga
    45241 agctattgaa aaaattgata attctaatct attgaacgaa gatggaataa tagttgtaga
    45301 acatgatacg aatgatttat ttccagataa gatatgtaaa ttggagaaaa ctagagataa
    45361 gaaatatgga aatactacat taacttttta taagatggag gcataatatg gaaaataaac
    45421 ctagaaaagc tatatttgca ggaagttttg acccaattac taatggacat ttagatatta
    45481 tttgcagggc ttcgaagtta tttgacgaat tacaaatagg agtattaaat aatcctaata
    45541 aaaagggtct atttagcttt gatgaaagag taaaacttat agaaaaaagt acaagccatt
    45601 taaataatat aaaagttgtg acttttgatg gtttattaat aaattactgt caggaaaatg
    45661 ggattggagc attagttaga ggtgtgagaa gtggtgctga tgttgattat gaacttcaga
    45721 tggcacatat gaatagagag cttaatccag atatagagac tataatttta ccaagttgta
    45781 caaaatattc atttataagt tcatctttaa taaaagaggt tttgctcttt gatgctgata
    45841 taaaaaattt ggttccaaag attgttttgg aagaattaaa gaaaaaaact agtgggggta
    45901 attgatatat gaagatagat ttagaaatga ttgaactatt tgagcagtta gaggagatat
    45961 ttagaagtgc ttctacaatc cctttctcac ataaatgcac agtggataaa gatgaggttt
    46021 tagcaataat taatgatata agaactttaa taccagaaga agtaacacag gcagtatgga
    46081 ttaataaaga aagaaataaa ataataagtc aagctaagca agatgctaca aatatagttg
    46141 aacaagcgaa aaaagaagct gagagaatac aacaagaata tcaagataat atagaggaat
    46201 taaagaaaaa ttctgaagat gtagtaaagg catatgtaga atccagtgaa cctgttgttc
    46261 aagcagacca aagagcaaaa gatatagttg atagagctga gagaatagcc aatgagataa
    46321 gaattgggtc aattgaatat gcagaggatg tgctttctag tgttgagtat aatttaagag
    46381 aaatattaga agaagtaaaa agagataaag ctgaacttag acctaaaaaa taaattttaa
    46441 ataaataaaa atggagctat cacacaaaaa attccaattt atgtgtgata gctctctttt
    46501 aatatagcaa ttttttgtta tataattgtg ctttttagat tacttatatc ttattttgat
    46561 attataatgt agtttaatct tttatttgtt gaaatcaact tatttatttg tataaataat
    46621 ataggttatt ttcaaatttt tttaataatt ttaccactgt cttcttttag attagagtta
    46681 gactgtgcaa aattataaaa taatactaaa tcatgtgcaa ttatttggta tggcactaca
    46741 tgtagaaaat atagataata aaattaagga ggtagtatga aggaaagggc taaaaaaata
    46801 ttagatttta ttattaaaaa taacaatgta acatcacaag aactacaaga aaagtttaat
    46861 gtttcaaaga gaactattta ttacgatatt ctagctataa atgaacaact aggaaaaagt
    46921 ggtaatataa aaaatgtaaa acacaaattt atatttgaag gtaatttatg tgatgcaagg
    46981 aaaataattt caactgaaga agataaattt ttagatagtg attacagaaa aacttttata
    47041 ttaaacaaga tattacttgg cgaaaaaata tcaatagaaa aactaacaaa tgaaatgtta
    47101 ctttcaaaaa acacagtagt acaaacaata actgatgtaa aaaaatacct tcaaacaatg
    47161 gggttaagat tagagtataa gggaaagtac aaaattatag gtgatgaata cgttattaga
    47221 gagctgtttc tgataattgt tcaagaaaat atattggaaa ttaattctat aagtgaggaa
    47281 gtaagtagtt tcgatacaaa aggacatata aaacttactg attattcttt attaaatcta
    47341 actaagtttg tggaatttct aaataaaagg ataagagatg ggaaaacatt atactcatat
    47401 aaatatctaa atgaagctaa aaaaattagt tactttagta attgtaaaga acttttatgt
    47461 gaagaagcta atgaaaatga acaagcctat atatgcactt acataagttc acttcccagc
    47521 ttaaatagtg aagttaagga agatgttgtt gaagaatatg tagataaact tatagataag
    47581 tttgaagtaa atacagcaat aaaattagaa agtaagcatg agtttaagaa aaatatttta
    47641 aggcacctcc attcttctta caacagaata cgatttaagt ttcctattag aaatccaatg
    47701 ttagatgaga ctaagtataa acatgagtca ctttataaaa ttataaaatc aattatagaa
    47761 aatgaagaag agtttcctgt atttgagggg ataagagaag aagaaatagg atttatagca
    47821 gcgtattttg gaggatattt aagagggtct agggataatg gtctaagaag aaataaagtc
    47881 ttactagttt gtcctaatgg tcttatggta tcaaagagtt tggaaataca actatataaa
    47941 tacataccaa ccatagaaat agtaggtata gtatccatta agcaactaaa agaagtaaat
    48001 gtatactacg attacataat tacaactata gatatacaaa atgtaaacaa cgtaattgtt
    48061 gtaaatcctc ttttaacatc atcagatgtt caattactta tgaacaaact aataagtgta
    48121 aaagaaaacg agaagtattt caatcttgaa ttaataatac aagctataag aaaaaatgga
    48181 gttatcaata atgaagaagc actaaaagct gatttattaa acataataca caagatagat
    48241 gaaggagaga tgtatcaacc aatgttaaag gaattaatta atgcagaaag ggtcaatata
    48301 ataaaaagtg ttagagattg gaaagaagca ataaaaatag cctcaaagcc attgttagaa
    48361 gataactcta tagaagagtt atatatagaa aatatgataa agtcagttga gaaatatgga
    48421 ccatatattg ttttagctga tagatttgct ctaccacatg caagttctaa agaaggagta
    48481 aacaagcttg ctatgtcttt actaatagta gaagatgaag ttgatttatt aggaaaacca
    48541 gtaaatatat ttatggtatt agctgctgta gataacacta ctcacattag agcattagca
    48601 tcactatcag agatgatgta cgaggaagaa aatgtaaaac taataattaa tggtgataaa
    48661 agttcaatac tagaacttat aaataagcaa aattaggagg aatgaaaaat gaagatatta
    48721 gcagtatgtg gttttggtgt aggttcatca atggtattaa aaatgacaat acaaaaggct
    48781 ctaaagcagt taggtataga atgtgaagta gaaaatacag atataaattc agctagaggt
    48841 gctgattgtg actgtatatt cacaagtcaa gaattgttaa atgaattaaa aggaacttgt
    48901 aatgtagatg tatatccagt taaaaagtac atggatttag cagaagtcac agaagttgtt
    48961 caaacttttt taagtgataa aaatgataag aaatagtata agttttaaaa agtaaattta
    49021 agttaatcag aataaaataa aaacttacta aattcaaaaa tagtaagaaa gagaggaggg
    49081 atttagtggt agaaaactta aacagttgac ctatcactaa aaaatataat gcttgatttt
    49141 atttcaaata atattttacg taatccatct atgttaattg gattaatagc agcatttggt
    49201 cttgtactac agaagaagaa agcatctgat gttataaagg ggtcactact tgcagctttc
    49261 ggaattataa ttatggagac tggaacaggt atgttagtta gttcaatagc accaattaat
    49321 ggagctttcc aaagtataag tggtggtgca gtaacaaaag gtttaagtga tgttactttt
    49381 actgcaagtt atggtggaat tataggttta gcaatgtttg cgggtttagc tattcaccta
    49441 atgatagcaa gatttactcc tattaagaca atctttttaa caggtcacat gctttattgg
    49501 ttcccattca tatttgtagc ttcaggagtt gaagctggat taaatggtgg agtattaata
    49561 gcttttgcag cagtattatc agcactctat tggtcaataa tgccttggtt attaagaaaa
    49621 tatgtgtttg atgttatagg agatgattct tttacattag gtcatccatc tggttgttta
    49681 gcacttatat caggatttgt tgctaaatta gtaggaaata aagaaaaatc tacagaagat
    49741 ataaacatac ctcaaagttt atcatttttt agagaaatat ctataagtgg tggaatggca
    49801 gtgtttttaa tgtttatagt tgttgggata gtaataccag gtgcgtttaa agatagtaat
    49861 gagtttattg gaacgtatgc aataaagcaa ggtctttctt ttggagcagg tcttataata
    49921 atgcttcatg gggtaagaat gctaataaat caaataatgc cagcatttca aggtatatct
    49981 gaaaaagttg tgccaaatgc actacctgct tttgactgtc caatattatt taattataaa
    50041 ccaaatgctg tattaatggg attcttagtt gctatgctaa catctacagc tatgatttta
    50101 atatgtaact actttaatgt atttaatttg ctacttatac cacttgttat aacttcattc
    50161 tttgagtgtg gagcagcagc agtaatagga gaatcacaag gtggtatacg tggagctata
    50221 ataggtacag ctatagctgc aatatttatg gtagttttag taggaatatc tgctgtaatt
    50281 tactcaggaa ctattcaaaa ttggatacta atatttggag gtaatgacct ttcattattt
    50341 ggtataatca gtaggtttat aggttcacta tttggaggaa tattatagat atgaaattta
    50401 aatacataga tgagataaga agattaattg atataataga aaacgaagaa aaagtcaata
    50461 tggaaaaagc agtacaaatc tttgttgaag caatagaaag taaaaatgct atattttcat
    50521 ttggagcttc acatgcagga atattaacag aagaattatt ctatagagca ggtggctgtg
    50581 ttcttataaa tccagtattt gcaaaatctc taatgttaga tacagcgcct ataactcaca
    50641 caagtaagat ggaaagatta gaaggatatg gtacagctct agctgataaa actccaatta
    50701 aaaaaggaga tgtagttata gttcattcag tatctggtag aaatccagta agtatagagt
    50761 ttgctatgaa agctaaggaa aataaggcaa tagtaatatg tataactaat ttaagttact
    50821 caaaaagtgt atcttcaaga cattcttcag gaaaaaaact ttatgaagta tgcgatttag
    50881 tgatagataa tcatggtcaa aagggagatg cctgtgtaga gatagatgga ttaaaccaaa
    50941 aagttagtcc aacttctact gtaatagcaa ctactgtgat gaactctatt atagctcaag
    51001 ctactcagga attagttaat aaagggctaa agaatcctcc gattttctat agtgcaaata
    51061 ttgatggtgg agatgagtta aataagaaga tttttgatga atataaaagt gtaattcatt
    51121 atgaatatta aggttaaaaa aatatgttaa tgaactttga agtttatcaa caaagaatat
    51181 taataatata taataaatgc tatcatttaa aagctgtagg taaaaatcta cagcttttta
    51241 ttattgtaga ttaaaaagat gcgtaattaa attttaaatt ggagaaaata aattggaagg
    51301 tatcaattat aaatattaga aacgttgtca tagaaaaaaa ctatattaaa aaaaagtaca
    51361 tagaaaaaac tgattagaca ataaatacat gctttgataa tattttaaat ggagtgaaaa
    51421 tgtgtagaat tataatgaaa aaagaaaata aaaatgaaaa aagaaaataa aatggaggga
    51481 ataaaagtgg gtatgttaaa aaaattatgt tcactagcta tggtagcaat tatgactaca
    51541 acacttataa cagggtgttc aagtggaaat ggaaaagatt caaaaaagga tggcgaaaaa
    51601 gaaaaactag ttctttggat gccaccagta gaaaataata tgaaggaagt ttgggaccct
    51661 attttagata aatttgagga aaaaaataac tgtgaagtag atttacagat aattccttgg
    51721 gataattatt ctgaaaaatt tgcaacagct ataagtgctg gcgaaggtcc agatgtagga
    51781 tatatgtatg cagaaatgta tccacagttt atagaaagtg gagcagtaga agatttgact
    51841 aactatgcaa ctaaagagga taaagagcaa tctatttata taaaaacatc tgaaatgatg
    51901 ggtggaatgt atggtatgcc attccaagca gcaaatccag gggtattata ctataacaag
    51961 gatattttag agaaactagg agaaaaacct cctaaaacat gggaagattt taaaagaatt
    52021 tgtaaaaaag caacgcaaga tactgatggt gatggaaaga tagaccaatg gggattagct
    52081 cagggatggg gagctaaaac ttttggtaac ttaaactgga actggtatcc ttatttatgg
    52141 caagctggtg gagatatatt taatgatgat ttaaaatcgg ttaaatttaa tgataagagt
    52201 ggtttagaag cagctaagtt cttaaaagaa ttacaagcat atgtgcctga agattcttta
    52261 tctaaagata gtaatgaaat gatagaaagt gtatttggac cagggaaagc agcatttaca
    52321 ataatgttat cttctgctgc aacaagtgta tttgatgaat cattcccgga tttaaattgg
    52381 ggatttgtaa ctggactaga agataagaaa gcagcaactt ttggagcagt agaccattta
    52441 tctttaatct catctgcgaa aaataaagaa cttgcataca agttaataca acatatgtta
    52501 agtgttgaat caatgacaga atttcataaa gcaataccaa gagcaccaat aacaaaaggt
    52561 gaaccatatc aaggtgatga aagattcaaa gaaatggtgg aaaatgacaa aaatgtatat
    52621 agaccattag tagtaggacc tcatggagtt gaaatatatg aatatttatg gaaagaactt
    52681 caaactatga tttcaggaga taaaactcca aaacaagcgt tagatgatgc tgcaaaatat
    52741 tcaaatgatt tattagcaca ataaaagttt aaagctgtaa tatgttgtaa agtactttac
    52801 agattaaaat tagcattgta tttataaata caatgctaat atttatattg gagaggataa
    52861 aatggaaaac ttagttagag agtttgaaga aaattcaaaa agaaaaaaaa caaaattaaa
    52921 tattaaacca tatatgtata tattgccatt gggaataatt ttagtggcgt tttatgtgat
    52981 accaataata atgtcaatat actttagttt tacaaagtat aatattatta gtccagctac
    53041 ttttataggt ttagaaaatt ataaaaaatt atttacagat gaaacattaa aagtatctat
    53101 tataaatact attaaattta ctgttgttgt agtaccttgc caaactatat tatcattgat
    53161 tttggctgtt tggattacag gaaaaggaaa tagtaaaata gcttcatttg ctaaaggtgc
    53221 tatatttata ccagtattat catctatggt tttgataggt atggtatgga gggctttatt
    53281 gaatggagaa ggttctatta tatatcaggt attaggtgcc tttggaatag aatcatctaa
    53341 acttttagga gatagtaaga cagcattacc tacacttatg tttatatcta tgtggaaaaa
    53401 tatagggtat ttcatggtaa tttatatttc agctataatg aatttaccaa aacactgcta
    53461 tgaagtagcg aaggttgatg gggctacaaa acttcaagaa tttataaaaa taactgtacc
    53521 tttattgaaa ccaactacaa taatggttgt atttttaggg tcgatatggt cattacaagt
    53581 atttgactta atttatactg tgacaggtgg aggtccaggt atatctacta tgagtatagt
    53641 tatgcatgca tttaacttaa actttaaaaa ctttaattct ggatatgcaa tgactgtagc
    53701 aaacgtatta tttttgttaa tagcagtagt ttcgatttta caaaataagc ttgtaaaacg
    53761 agacaattca gatttttaga aaggtaggta taatatgaaa acagcaagaa gattattaag
    53821 tgatggttta cttttattta tagcgtgtgc aagtttggta ccttttatat acatgttgat
    53881 aatatcattg aagataacat ataactcata tagtttggat atatcttttt caacagtaac
    53941 ccttcaaaac tatatagata tttttactaa aaaaggattt gcacaatatt tttttaatac
    54001 agcaatagta tctttttcag gtgtattatt aaatttagta tttagtacat tagcaggata
    54061 ttcttttgcg aagatggatt ttaaaggtag tgataagtta tttttattta tgataatgac
    54121 tttaattata ccttcccaag ttacaatgat accactatat ataataatga aacacttagg
    54181 atggataaat agttatcttg cacttattat gccaatacca actgcatttg gcgtatttat
    54241 aatgagacaa gctattttag gagtaccaaa agagttatta gaatcagcaa agatagatgg
    54301 ttgttcggat tttagaattt taatacaaat agtgttgcct ttaattaaac cagcattaat
    54361 tacactagca atatttactt ttatgggagc atggaacgag tttatgtggc ctcttatagc
    54421 tacaactaaa gatgcaatga gaacattaac agttggatta tctactctta agacattcca
    54481 gataactaat tatggacaga tgatggcagg ggctacaata acatttttac ctccatttat
    54541 tttctatttg attttacaga gtaaatttgt tgaaggtgtg tctttgtctg gtataaaagg
    54601 ttaaatagtc taatttaata atatataaag aaacttatat aaatatggag gaatttaaac
    54661 tatggaaatt tcatatgtac tgaaagattg cacattcaaa cacaataaat actcagttgt
    54721 agaagctgaa acttggaaag ataaggattt ggatattgta gtagctaaag gtgaaaaatt
    54781 tgcatttcaa attatgttaa aagcaacaga agaatttaat tgtacaattg ataaaagtag
    54841 tgctatatca tggaaaggcc tgggaaatag agtaaggtta gcattaaata tgcctaatag
    54901 tttagaaaat aattttagta taaatatatt aggatatgtt caagatgata caaaggcatt
    54961 tgtgaatgat gctattttaa gggataaaga tgtgttagta gagcaatatt tgcctcaaac
    55021 attttggatt gaaggtcaag taccagaaga ttttgaagaa aataaccttg atataggtat
    55081 tgatatattt aaaagctttg gatatgaaga tgaagaaaaa gtttgtacaa ttgatgttcc
    55141 tgtaaaagta agaaatgttg tgctaaagcc tttagatgaa agcaagttct ttttagattt
    55201 atggcaacat ccaagctgtt tagctagaat gtataaagtt gagttatggt ctgatataca
    55261 ttttgaaata gtcgataact atttaaaaga attagcatct ttaggagaaa aagttgcaac
    55321 agttatagtt tcagattatc catgggcagg gcaaagttgt tataaagttt ataaaaatcc
    55381 atcaaactta tatgaatata acatggtaag tgtatcaaaa ggattggatg gaaagattaa
    55441 atgtaacttt gagagtatgg ataggtatat aggcatagct gataagtata aaatggctaa
    55501 ggagatagat ttatttggtc tattaggtaa ttggtgtgct ggtgagtttg gaaatcctgt
    55561 agaaggttat aaggacccta taagagtaag atattttgat gaaaaggata aagtatttaa
    55621 atttataaac aatacaaatg atttaaaaga atatatagga ttagtattaa atcatttaat
    55681 agagtgtgga ttatgggaca gagtaaggat tatagctgat gaaccaaata atccagaagt
    55741 agtcaaagag tgtatagaat ttataaattc tactgtaggt actcatcaag ttaaatataa
    55801 atcagcaact cacgaccaaa actttttaga cagagctaaa gatgaaattg atgatatgtc
    55861 aataaattta aaacttacta tacaaaatta taaagatata gaaagtctta agaaaaaaat
    55921 caatgacaag ggtgggatat tgacttggtt tgtatgctgt tttccagaaa aaccaaatag
    55981 ttttttaagt tctccttttg tagaaaatag aataatagga tggtatactt attactttgg
    56041 tcttgatgga tttttaagat gggactataa tttatggaca gaagaccctt ggaaagattc
    56101 aagttacaaa ttccctattt ggaaagctgg agatatgttc tttgtttatc ctggaaaaga
    56161 tttaaagcca gttagaagtg tcagaatgga gaatttaaga tttggaatac aggattttga
    56221 gttatttaca atgttagaaa aagaaaaggt aagagagtat atagaagttg agcttatgca
    56281 agaattatta aataaaaaag aaaatgctga aattaaaggt tttggtgaca tagaactagg
    56341 atattcactt gataattgga gatatgataa agttaaaaaa tatgtattag agttgttaga
    56401 cagagtataa aaaatataag agtgtctcaa aatgaacttt ttagttcatg aggcactctt
    56461 tttgtatgaa atcaatatag tttcattgtt tcaacaatga aaaataggat tatttctatt
    56521 ctaagacagc cctttagttt tttagttgta ttcaatgttt taaaactaac tataaacgct
    56581 ataaagttta taaatgacaa taattatata taacatgatg tactttaatt tgctataata
    56641 gggattgaat aatattatat ggaagataac attgtttggg gggattaata taaaaagaat
    56701 aggtattatt ataatgtttt ttttaagtat atcttttatt ggattttatc ttgtaataag
    56761 agataacagt gatacagtta agatgcaacg agggataaat ataggtaatg cactagaatc
    56821 acctaaggat tttccgtggg atgtaaaaat gtcaaataag ttttttgatg atataaaaga
    56881 tgcaggtttt gacacagtac gtataccagt aaggttttct gattatacgt cagattctga
    56941 taattttaaa attgatgaag aattttttaa aaagattgat aaatatgtag attatgcatt
    57001 ggataaagac ttaatagttg tgttggattt acaccatttt gaagaaatta tgaaagaacc
    57061 aagagttcat aaagaaaagt ttttaaaaat atggcaacag atagctaata ggtatcaaaa
    57121 atatgataaa aaattggtat ttgaattatt aaatgaacct aaagaaaatt tatcttcaca
    57181 attactaaac gaatacattg aagaagcaat aaagataatt agaaaaacta accccaaaag
    57241 aactattata gtaggaccat ataatttcta tcaaattgat tatttgaatg aattaaatat
    57301 tcctaaagat tctaatatag tagtttcttt tcactattac gagccaaatg attttgcatt
    57361 tcaaggaaat atctatcata agggatttga gcacttaagc aatattactt gggaaggaac
    57421 aaatgaacaa atggattatt taaaaaaaag gtttgatact gtggaaaatt gggcaaataa
    57481 aaataaggta aaaatcttct tgggtgaatt tggaataaca aaagaggcac cagaagtttc
    57541 aagaagagca tggataaaag ctgtaagaga agaagctgaa aaacgaaact tttcatgggc
    57601 ttattgggag cttgcatctg gatttggtat atacaatcaa attgaaggga cttgggatag
    57661 agatatatta agtgcattaa tagaaaagag gtgattttat gaagaaaaat tcaaaaaaga
    57721 tacttataac tttaactatt attactaatg tcatatatat attgtggaga attttttaca
    57781 cagtacctaa agaagaaggg aagtttgcct taatatgtgc cataatactt ctttttgtag
    57841 agataatggg tatgatggaa atgtttgtgc attattatgg tatgtcaaat attgagtatc
    57901 ctgaaaaacc aatcataagt gaagaacttt atccacatgt agatgtattt attgcaacat
    57961 ataatgaatc tgttgatttg gttagaaaaa ctgtaaatgg atgtattcat atgcagtatc
    58021 cagataagaa aaaggtacat atatacatat gtgatgatgg aaatcgtgaa gaaatgcgta
    58081 ttctagcaga aaaaatgggt gtaaattaca taactagaac tgaaagagaa ggagcaaaag
    58141 ctggaaattt aaataatgca atgcaacata caacttctcc tttgattgct acatttgatg
    58201 cagatatgat accaatgcat gactttttaa ttgctacagt accatacttt ttaaaaaatg
    58261 agcaagctaa aaaagatgga gaaaaagagg agtatgaaaa ggttggtttt gtgcaaactc
    58321 cacagagttt ttataatcca gatttgttcc aatttaatct gcactctgaa ggaaggattc
    58381 caaatgagca agattatttt tacagagata ttcaattggc tagaaatagg acaaattctg
    58441 taatttatgg tggtagtaat acagttattt caagggaagc acttgaagaa gttgatggat
    58501 tttatactta ttctattaca gaagattttg caacaggtat cttaattcaa agtaaggggt
    58561 atagatgtta tgctattcca gaagtacatg catcaggttt atctcctaca gatttaaaaa
    58621 gtcttattaa gcaacgtgaa agatgggcac gtggatgtat acaaactggt agacgtctaa
    58681 atattttgtt taggagaggt ttaggttttt ggcagaaaat aagttatatt tcttcaatta
    58741 cttattggta tgcaagtata aaacgctttg tatatataat ggcacctatt ttattttctg
    58801 tgtttaatgt gattgtagta aaatgtacgt tacttcaagt attggtattt tggttgccaa
    58861 tgtatatttt aagtagttta tctcttaaaa tattttctca aaatataaga aatactagat
    58921 ggaccaatat atatgaaact ataatgtttc agtctttaat gccagcagta atacttgaaa
    58981 cgtttgcaat atctaaaaat aaattttcag taacaaataa gagtaaatta gaagaaaata
    59041 gaatgtataa gtttttacag ggaatacctt attttattta catggtctta tctatcatag
    59101 gaattttaaa aatgtttgta gcaatattta aaatgagttc aatgacatat tcagttgtat
    59161 tattttggtt gattggaaac ctttttaacc ttgttatggc tacattattt atatcaggga
    59221 gacagcagtt aagaaagtct gagcgttata ttgctgaaat tgattttaag ttaaagcaaa
    59281 attcttatgt tctttcttca aaaacaattg atatatcaga aaatgggttt gcatttttgc
    59341 tagaaaatcc agaatatatt tcaccagaag aagagtttga ggtagagttt agagaaaaat
    59401 ctggaaatga aatgtatata gccaatatga aagcaaagat tgttaatgtt gtggaagtaa
    59461 attcaaagtg gaaatatgca gcttatatta cacatattga agatagtgaa atagataatt
    59521 ggatgtgtat tgttcacgat agaataccta ctttaccaat gacaatatct aatcaactag
    59581 gtttctttga tgatttgcaa attaatgtga aaaaacgtat tgaaaaaact agaacattat
    59641 cacgaagaag tccaagaatc aatatgaatt ttcagatgga tataaaaaat acaggtaaat
    59701 taagaatagt gaattttaat tatcaatatg tattattaaa ttttgagaat aaaagtattt
    59761 atcctaaaga aatagcattg gaaattaatg aaaatattgt gttagaatgt gatttgtgtg
    59821 agggtaaaat tgatgaaaga ggtatcttat ataaagtaaa taacattgac agcataatgc
    59881 aaaatttctt tttaagagat gaaatgatgg attggatatt acaaaataag acaattcttg
    59941 tttcaaagcc tagtgaaaag aaggaaaaaa gtatagatga gtttgaaccc atggaatata
    60001 tttaggagag atgaaatgaa gactttaaaa gtgttttttt gttctacaaa atatcttatt
    60061 ttggtgttta ttttttttat aaatactact tttataagtt cagcaacaag tgataaaatt
    60121 ttagatttgt cctttaaaaa gatagagact gacttaaatt ctaagattac atatgaagat
    60181 acaggtgtaa aaatagaaac ggatagttct aaaagcgata aggaacgtta tttatatatt
    60241 taccaaaata taaaagaaaa ttggagcatg tataataatt tttatattga aattcaaaat
    60301 aaaaataaaa gttctcagag aataaattta agcatacaaa gtaaaaatat gcttgaattt
    60361 agattaaaag aaggtagtga agtattttta gaaggtaaaa atataatata ttcagataaa
    60421 ataaaagaag gatgcataga agtaccaggt gaatttgaag gcaaaattta tgtgaacttt
    60481 aatagcctta taaatgagga aagtaatgtt gtgctggact caaatatgct ttcaaacatt
    60541 gttagttggg gaattacgtt tattccatct gatgaagaac ataatattgt tattataaaa
    60601 aagatatctt tattgtctga agagaaatta agatttttaa ataatattaa aataattggc
    60661 gatgaagaag tacaaatacc agtattgggt caaagtataa gtcagtatga agtattaggt
    60721 cttaaaagtg attctaaaat taagtactct cttatgggaa aacaagataa tgtaagcata
    60781 tctcaaaaag gtaaattaac attaagtaat aaagccaaac ctggacaaat tattttacaa
    60841 gttaatgttg atgataagtt taaaattgga aagaaaataa cattaactga gtcttggagt
    60901 gttaataaaa aagataagga tggtgttcca tatacattag tatatcctga gcaatcacca
    60961 acagtacaag atatgaaaaa aataaacttt atgaataaca tcataacgtt tgttcgaatt
    61021 ttatttgtat ctctagtaat aatatgcttt ggaatatatt tatattggaa aaaatgttca
    61081 aaaactaagt aaagagagga ggttagattg tgttattttc aagtttaatt tttttatttt
    61141 attttttacc tataactttg gttttatatt atgtatttag gtttaaccga acgatacaga
    61201 acatgatatt gcttgctgtt agtttatttt tttatgcttg gggagagcca aaatttgttg
    61261 ttatcatgat agtttccata ataatgaact atatatttgg tttactggta gatagatata
    61321 gggaaagtaa aataaaagta aaagtttttt tagttttgat gtgtgcatac aatataggtg
    61381 ttttatttat atttaaatat ctagcttttg cgctaagaaa tattagtgaa cttattagta
    61441 ctgaattgac tatacctagt attgttttac ccataggaat ttcatttttt acatttcagg
    61501 gaatgtctta tgttatagat gtatatcgta gacatggaga agtccaaaag aacccttttt
    61561 atgtgggatt gtatatagca tttttcccac aattaatagc aggtcctata gttagatatg
    61621 agagtgtggc agaacaaatt ctcaatagaa aagaaacttg gaataaattt tctattggga
    61681 cttgtaggtt tataacaggt ctaggtaaaa aagtattaat ttcaaataac atggctatag
    61741 tagcagacta tatttacact atgaatagtc aaggagaaat agctgcatca cttgcatggc
    61801 ttggttcaat agcctatact ctgcaaatat tctttgattt ttctgcttat tcagatatgg
    61861 ctataggctt aggtcttatg tttggtttta aatttgaaga gaactttaat tatccatata
    61921 tatcaaaatc aattagtgag ttttggagaa gatggcacat ttctttggga atgtggttta
    61981 agagctatat atactttccg cttggaggtt ctagagtagc aaataaagat attatgatta
    62041 gaaatatgtt tatagtgtgg ttatttactg gaatatggca tggagcagaa tggacatttg
    62101 taatttgggg gattttaaac tttgttttcc taattataga gcgatttata atgtttgaaa
    62161 agattgaaaa tcacaatttt ataaaacata tttatgcttt attagtagtt aattttgggt
    62221 gggtattatt taggtcacct aatttaaaag aagcatataa ttattttaaa gctatgtttg
    62281 gaggcaatgg agctatatgg agtgattata catatatgtt tttaaaagaa tactgggttt
    62341 tctttatatt tgcatttatt tttagtgtac ctattgcaaa gaaaatcaat aagtttgttg
    62401 ttgaacaagc taaatatagt atgatattta acgtatttta tccaatctca gctattttat
    62461 tgttttttat ttctgtgaca tatttagtaa ctggaagcta taatccattt atttatttta
    62521 atttttagtt gggaggaaaa gtatgaatag attttttaaa gtaagattaa taactgcaat
    62581 tatgttctta attattttat tcgctttctc tatctttaat gtttgttatt ctggaaaaga
    62641 tacgatacag gaaataaaaa attcaatagc tgaaaaaagt agtttaaaag atacaatatc
    62701 atctattgat aatacagtga atgacaaagt aatatacaaa aatacgttca ttgaaactta
    62761 tggctattta caaaaattaa tgggtaaaaa tgagttttca aaatttagtg ttgtaaaaga
    62821 tacttctgga aagatgcatt atacatattt tgctaaagct ccaaatccag ttggtgtgat
    62881 agcagatagg gtaagaaaat tttctgatga aatggaaaag caaaacacta aattggttta
    62941 cctaatgact ccagataagt atataaaagg agtgacaaaa tttccaaaag gaatacctta
    63001 ttcttatagt aatgagacag cagataattt tttaaatcaa ctaaaaaagt ataatgtgga
    63061 ctatattgat tttagagaaa atattttaaa gagtggtatt ccaaaagatg atttattttt
    63121 taaaacagac catcactgga aagtagaaac ttctttttgg gcatttggag aattagttga
    63181 gcaacttaat aaaaaataca atatgaattt agatgaaaat cattattata gagataagga
    63241 caattataat tcaattgtat atcctaagtc atttcttggt tctatgggaa gaaagactgg
    63301 tatcttatat ggtggtatag atgattttac attaatttat cctaaattta agactaatta
    63361 tacttattat acagattcta aatctcaaaa atttgaatta aaaggaaggt ttgaagagag
    63421 tttaatatta tcatatcctt ttaatgcaga ccttgattta atggatggtc aatcagataa
    63481 gtattttaca tatttattgg ggaacagacc attagttaaa ataaaaaata tagaaaatcc
    63541 agatggatta aaagtgctgt ttgttaaaga ttctctaatt gtaccaacag cagcattttt
    63601 ttcctctgtt tgttcatcta tagatatgat agaccctaga tattatgatg gagatatact
    63661 agaatatgca aaatcccatg actatgactt tgtttttata tctgtatatc cccaaaatct
    63721 tacaaaagaa ttttttccgt tttgtgagta aatttctaaa aaagttttct gataaaataa
    63781 atggctaact ggtaaaaagt tagccattta ttttgagtgt tattctaaga aatatttttt
    63841 ttactaaata cttctttatc tatttttcca agtgattttc ctacagtaat tgatgatacc
    63901 atagcaccat taacatttat catagtacgt cccatatcta gtatagggtc tattgcaagt
    63961 ataccaccaa ctaatggaaa ataagaacca agaccaactc cagagataac aactgaaacg
    64021 gccattgtag cagttcctgg aagaccagct attccaaacg aactaattgt tataacaatt
    64081 aacaacataa cataaaagct catatccatg tttactccag ccatattggc aagtgttaca
    64141 gccattaaag caggatatat acctgcacaa ccattcatac ccatatttgc acctaaactt
    64201 gctgtaaagc ttgatacacc ctcatcaact ccgtgatttt gtactagact ttctatcgtt
    64261 acaggcaatg ttcctaaact agaacgtgaa gtaaatgcca gaagtaaagc ttcagttgaa
    64321 ttttttatat aagtaatggg atttagacca tttaaagtta taaaaattaa atgtataata
    64381 aataatattg caactgatat ataaagagct aatataaact gtaaaacaga tactattgaa
    64441 ctaatacctt gtgaagttat tgtatttgca agcagagcaa ccacagcata aggcataaat
    64501 ttaataacag tcatagacac acttacaatt attttgtaag atgcttctat aaaacctata
    64561 aatggtttta ttgtttcaaa atgtttttta cttaatctct ttattgaggt agctataaat
    64621 gtagcaaata ttattgtagc tacaatattt ccatttgcca tagccattac aggattagat
    64681 ggtagtaatc ctcttaaagt atccacaaga gagtttattt ctttaagttc ttgattttca
    64741 actaaagtag gcatattagc tcctacacct aacttcatta tatttgcaac gataattcca
    64801 acaattgcag ctatagcagt agtagcaaga agcataccta aagatttaaa tgtcagagtt
    64861 ccaagattgt tatctttcat atttataatt acttttataa tggataagaa aactaaaggt
    64921 actactaaca tttttaataa gtccataaat ccagaaccaa ataggctata ccacttactt
    64981 acttcttgta gccaaatgac ttgagttgta tcattaggaa aaccagcaaa agcttgtatt
    65041 atgattccca atatgagtcc tagtactgta gcatatattg ttctcaatga aaattttatt
    65101 tttttctttt caaattgtct aacaataaag aacgtaccta gaagtaatat tatgaaaaaa
    65161 attgttttaa aatctgtaat cataagaaat tgtgataaaa atgaactttc caatattttt
    65221 ctccttttat ttaaaaataa atttttctaa gtttaaatga tatcaatata ttaaaaaaat
    65281 gtcaatatta tatcacaatt tacttaaata gagtaaaaca agttgatttt gaaaaatgtg
    65341 attaagtaca gaaaaatagg gtataataaa tgtttaaaga atttgaattg tggtaagaaa
    65401 ataaaaaata gcttttataa gatttgattt caaattaaaa tgtgttaaat aaataactaa
    65461 aaattattat aaaaaatgtt ttcatagaat atatatcaaa tgaaaagctt aaaataagtg
    65521 aagaaattaa ctagacatca aaggagagat aaaatgagag taataataat tggtggtgtt
    65581 gcagctggta tgagtgctgc agcaaaatta aaaagaataa aacctgagta tgaagttgtt
    65641 gtttatgaaa aaactgaaat agtatctttt ggtgcttgtg gattaccata ctttgttggt
    65701 ggatttttta atgatgctga tgaattatta gcaagaacac cagagaaact tagagaagct
    65761 ggaattgatt taaatatatt tagagaagtc gttgaggttg atagtgaatc taagaaaata
    65821 aaagtaaaaa acataaaaac agatgaaata tatgaagatt actatgataa attgatgata
    65881 gcaactggag caagaagtat tatgcctcct ataaaaaaca taaaattaaa gaatgtttct
    65941 acattaaaaa gtttatatga tggagaatat ttaaaaaaac ttttaagtaa tgaagataat
    66001 aaaagagtga caataatagg agctggtttt atagggttag aagcagttga ggcatgtaag
    66061 aaattaggta aagatgtaga tgtaattcag ttagaagata gaatattgcc acaagtattt
    66121 gataaggaaa tgacggatgt attagaagaa gaaataaata gacataatgt taatttgcac
    66181 ttagatgaaa tggttgtaga actttgtgga gaagataaag tagaaaaagt tataacaaac
    66241 aaaggggaaa tagatacaga tgtagtaata attgctactg gcgtgagacc taataccgag
    66301 tttttgtcaa atactaatat aaaaatgcta aaaaatggag ctatagtagt tgatgagtat
    66361 ggaagaactt ctgtagaaga tatatactct gctggagatt gtgcaactat aaagaatata
    66421 gtaagtaatg aaaatgtata tgttccttta gctactggag ctaataaatt gggtaggata
    66481 gtaggagaaa acctagcagg aagagaaata tcttatcaag gttcactatc ttcaagctgt
    66541 ataaaaatta tggatatgga ggcagcatca actggaatta cagaaaggca agctaaagat
    66601 ttaggcataa atgtcaaatc taaatttatt tctgattata atcaaactca ttattatcca
    66661 ggaagaaata aaatatatgt aaagcttatt tatgatgcag atacaaaagt tattttaggc
    66721 ggacaagtgg ctgggtttaa ggatgctgtc caaagagcaa atgtattggc agctgctatc
    66781 tttggaaaaa tgaccacaaa tcaacttgga atgttagatt tatgttatgc tccaccattt
    66841 gcaagaacat gggatgtttt aaatgtagct ggaaatgtat ctaaataata tttagattat
    66901 agctaatata gttgacaagc aattaaggga atgaatttac ctaaactatt tttatcatgg
    66961 taaaattcat tcctaaattt ttattccaaa tttttattcc aaatttttag aaataaggat
    67021 tccattaaat tattcatcaa aatttaaacg caagcttaat ctatcttctc caagaatagt
    67081 attttcaaaa acattagtag cattttctaa atacatacta ggtatgtcta aagaaggact
    67141 aaaatgagtc agtaaaagtt gtttgacatt tccaagtttt gcaagattag cagcttctct
    67201 aaaagtcata tgtttgtttc taacagcttt tgatatatct aaatcatcac catacatggc
    67261 ttcacatata aataaatcac tatcttttat gaaatctggt attgattcta taggtcttgt
    67321 atcggttgta agacttatct taactccctt tctcaattct cctaagacca tatctggagt
    67381 gtattgtttt gaatctaaaa ctatattttg accttcttgg agtttgttcc ataatatttt
    67441 aggaacttcg tttttagttg ccttatctat atcaaattta gggtttcttc taaaattaaa
    67501 actgtatcct aaacactcta tagagtgttc taaactgatt gttgaaattt ctaaatttct
    67561 taaaacttta ttatctaaag aaaaattgcc ttgagggttt tctataattt ttaaagtgta
    67621 tggtacatat tctactaaat ttctcataga acgtatacaa tcgactattc caactggacc
    67681 aactatagtt aaatcacttg tacgaccact attcccaatt gttgataaaa gtcctaaaag
    67741 tccaaatata tggtcaccat gtaaatgggt tatacaaatc aagtctatat ctttaaagcc
    67801 acattttttt agcttcatag atacctgagt accttcacca cagtcaatta gtatttttct
    67861 acctttatag tttataaata cagaggatag aaatctgttt ggcataggta catttccacc
    67921 acatccaagt aaagttaaat ctatcatttt ttcccctttc taaaattaac acaaatctgt
    67981 tgtttgtttt tattatgata tcctattata attattttaa cattaaatat aacaataaat
    68041 gtgtatttga gtcaagaaat attgtcaaat aaagttttta tatagcaatg tataaaaatt
    68101 tggaaaacga aaagtgaaaa ttatatttag gagtatttaa aggaggaaaa tttaatgaaa
    68161 gtattaaaga aaattactat tttgtcatta attacattaa ccttagttgg ttgtagtaac
    68221 ggagaagaga aaaaagtggt tgaaggttct aagaaaactc aaaattctaa aaaagatgaa
    68281 cagcctataa tagtacataa agatgcaaat atattgaaag ataggtatga gccaccaaaa
    68341 ggatttaaaa gagttgatgt agaaaaaggt agttttgaat catttcttag gaatactaag
    68401 ctaaaaaatt atggagagaa agtaaagtat tatgatggaa gaactaagga atcaaaaggt
    68461 atttatgata gtgtatttga tgttgatatt ggaaatagag atttacatca atgtgcagat
    68521 gcaattatgc ttatgagagc agaatacttg tatcagaata aactatatga tgaaataagt
    68581 tttgattttg ttgatggttt taaggcgaag tattcaaaat gggcacaagg atatagaatt
    68641 tcagtaaaag atagtggttc aagctggtat aaagcaactg aatattcaac atcttatgag
    68701 agtttcagaa agtttatgga tatagtgttt gcatattcag gaacgttatc tcttgaaaaa
    68761 gaattggagc ctgtaaaagt tgaggatatg aaaataggag atgtgtttat agttggtgga
    68821 agtccaggac atgcaagtat aattatggat atggcagaaa atgaaaagac tggtgaaaag
    68881 gtatttatga tagcccaaag ctatatgcct gcacaacaaa cgcaacttct tattaatcgt
    68941 aaaaatccaa atttgagtcc ttggtatagt ttagattttg aaggtgattt gacaatacct
    69001 caatggactt ttaaaagaga ccagttgaaa agattttaaa ataataattt tatataataa
    69061 aagaaaaata tagatgtgaa aaaatgtaat tagattaaaa ctaattggat atggacaaaa
    69121 ttaaattgat agataaatat taaaaattac actaattaat cttactatag tttaatattt
    69181 atctaaaaag ttttatgtaa aatataaatt ttatattaaa gctaaaacta atttgaggag
    69241 gctaatttat attgaagatt agaaggtatt taattttggt aattataatt ctaattacaa
    69301 caagtcagag ttttatttct tatgggctag agcgatttga agaaataacc atttttcaca
    69361 ctaatgatat acatggaaga tatgctgaag gtgatgacca tatacaaata ggaaatctag
    69421 ccacattgaa aaaagaaact ccaaactcaa ttttagtaga tgcaggagat tgtttgcatg
    69481 gacttccaat agtaaatatg gatagaggga aaagtgcaat tgaattaatt aaatgtgctg
    69541 gatatgacta tattactcct ggaaatcatg actttaatta tggaaaagat agactgtttg
    69601 agttatctaa aagtgctaat ttaggagaga atactttaaa atttttatca tcaaatattt
    69661 ttgaaaatgg gaaaaaagtt tttgatagta atgatataaa agaaatagat ggaataaaaa
    69721 taggattttt tggactctca acccaggaaa caaagagcaa aactggattt aaaaatgtgg
    69781 aaggattaga gtttaaaaat cctatagaaa gtgcaacaga acaagtaaat gaattaaaag
    69841 gaaagggtgc caatgtaata gttgcaatat gtcatattgg tacaaatagt ttaagtaagc
    69901 caaatagtat agatatagca aatgaggttc aaggaattga tttgattatt gatggacaca
    69961 gccacactaa gtttgaaaat ggtaaacaag tgggtgatac attgattgta agtgcaggac
    70021 aatatttaga aaatattggc gagataaaac taactttgga tactaatgat gtagaagata
    70081 taaaaataga aaataaatca gctagattaa ttggaaaaga agaagcatta aagtataagc
    70141 ttgactccgt tgtaagtaaa aaggttgata aaataaaaga acaacaagaa aaaatattag
    70201 ataaagttat aggggtaact acaaatactc tagatggttc atatgaaaat gtaaggacaa
    70261 aagaaactaa tttgggtaat ttaataagtg acattttact agataaaact aaggctgata
    70321 tttctttatt taatggaggg aatattcgag atacgataga aaaaggcaat ataacaagaa
    70381 gagatattgt agatgtattt ccttttagca atactatagt taccaaagaa cttacaggag
    70441 cacagattaa agatgtattg gagcatggag taaaacttta tccagaaaaa agttcagcct
    70501 ttttgcaagt gggaggaatt tcatattact ttaatcctaa acaaaaagaa ggcgaaaaaa
    70561 taacaaatat tcaaaaagaa ggaaagccat tagatttaaa taaaaagtat gtagttgcaa
    70621 cgaatgatta tatagcatca ggtggagatg aatttccttg tttttcaaaa gagccagtac
    70681 taaaggaatt tggaaattta gagagtgcag tcattgaata tatagagtac aaaaaagaaa
    70741 tatcaaaaaa tgtagatgga agaattggta ttaaatctaa agatgagtta ataagcaaga
    70801 atcatgagag tgatttgata ttaagtgaaa atgaaaaaaa tatcaatgat aatgaagaga
    70861 atctatctaa taatataaaa agctctgata gtgataaaaa taaaagctta gataaaacaa
    70921 gttctagaga aagttctaat ctaggaatat ctaaaagaga agctaaagaa aaatctccta
    70981 aaacaggaga tttaggtttt tcaaatagta taattatatt tatagtttca agtacattga
    71041 tatgtttatt gaattttaat caaaaagagt taaaggataa aaagtcaaaa taaaaattaa
    71101 tgagcaaaaa ttagtagata gtaatttaat tttagataat agtaaacagc aaaggaaatt
    71161 agttatataa atactaattt cctttgtttt atgttttaac atgattactt ttaaataaaa
    71221 ttgtatttta tgaaaaataa ttatactaaa tggcatagta ttatggggat ttttagtttt
    71281 tattcaagta aatgaaatca tattaacaac ttctgatata tttacaaatt gataaaaaaa
    71341 tgattttatt agtatgatat aatttagcta gtatgtatga taatggagga tatagggatg
    71401 aataatatat tacttttgga agatgacaaa tctttaaata gaggaattag ttttaaatta
    71461 aaaaaagaag gatacaatgt ttttagtgca tttggtatag aagaagcaaa aaatattttc
    71521 gcaaaagaag agatatgctt aattatttcc gatataggtc tacctgatgg tagtggtttt
    71581 gacttttgtg aggagattag aaagaaaagt gatgtttaca taataatgtt gacagctctt
    71641 gatgaagagg tggatattgt cacaggatat gatttaggtg cagatgatta tatcacaaag
    71701 ccttttagct tgatggtatt aatatcaaaa gtgaatgcgc ttatgaaaag agtaaataca
    71761 gtaaaaaatt atactctatt agtttgtgat gatttattct tttattatat agaaaataaa
    71821 ttaattataa gaacagatga taaggaagaa gagataattt taagtaagac agagacaaaa
    71881 ctattaaaat atttgatgga aaattctatg cagacattga ctaaagagca actgttagaa
    71941 tctttatggg atagtagtgg taattttgta gatgataata cgattgcagt aaatataaga
    72001 agacttagac aaaaggttga aaaaaatcca tctgaaccta aatatataaa aacagtaaga
    72061 ggggttggat atatgtgggg agaaaggagt ataaaaaaat gctaaaaaat atgaacctca
    72121 aagatggttt aagtgtgaaa gatgattata taatgagaag agttattgta tattctgttt
    72181 tatctgtact aatagtaacc cttgtattta tactttttga atatagcaga ttacataaat
    72241 tgtatgaaca tcaaataaaa aatactcaaa atgttgctgg aatattgatt gaaaaatatc
    72301 ctaatgatga aatagatata gtaaattcta tttataattc tgattatagt aaggtgtcta
    72361 ctggagaaaa ggcatttaag aaatttggct atggattgga aaataaaatg tcaaatgata
    72421 aaaattttag cttatactta aaatcttttt ttaaggaatc attttttatt tttttaatga
    72481 tgtttatagt agttataggt ataatatatt attttataag atacataaat aaaagattga
    72541 gtaaaattta ttttatagta gataagatgt cacaagaaaa ctacttgaag gacactactg
    72601 agtcagaaga aactggttat ctagtagaat ataatgaata ctttaaagaa ggcatattta
    72661 gtaagataaa taactgtcta tatgagctta atagaagttt aaagataaag tttattaaat
    72721 tagaaaaaga aaaagaaagt gtaaaatcat tagtaacaga tatttcccat caattaaaaa
    72781 ctcctttagc atccttaaaa ttatacaata cattacttat agaagaagaa ttagaagaag
    72841 atgaagccaa cgagttctta ttaaccaata aggcttctat aaataaatta gaaaatttaa
    72901 taaattcttt agtgaacata tcaaggttag aaattagcat gataaacata aaaaaagaag
    72961 ataatgatat aaaaaatact attctaaatg cagtaaaaag tgttacccct aaggctaaga
    73021 gcaaaagtat aacattaaat ttaaatgaat ttaacagtag aattatacca catgataaaa
    73081 agtggactga ggagagtatt tttaatgtat tagacaatgc tgtaaagtat acacaggtaa
    73141 atggagaaat aaatatatct gtagaagaaa ctgctaattt ctttaaaatt ataatagagg
    73201 ataatggcat agggattgaa aaaagtgagt ttaataatat atttaaacgt ttttatagag
    73261 gttctgctga tgaaattgaa tctgtagaag gtagtggggt aggattgtat ttaagtagaa
    73321 agattttaga agaacaaggt ggaaatatta tagtttcttc aaaagtagga atagggagca
    73381 agttttcttt gtttcttaca actatgtaat attaaatgaa aggaaaatgt aagcctctac
    73441 atttattata taagtataaa cagctccaga aataaaaaat taataaaata tggagtaata
    73501 taacttagaa tgagaggata attttatgaa aatactatat actgaaaatt tatcaaagca
    73561 ttatggaaaa ggagaaagct tagtaagagc tttggacaat gttgacttag aaataaatga
    73621 aggtgaattt gttgcaataa taggaaaatc aggttctgga aaaagtacac ttttgcatat
    73681 gattggaggt cttgatatac ctacatctgg gaaggtgtat atagataata aaaatatatt
    73741 tacattaaaa gaagaagaac ttgctgtatt tagaagaaga aaaatagggt ttatatttca
    73801 aagctataat ttaattccat ctcttaatgt atgggaaaat gtagtgttgc caatcggttt
    73861 agatggtaga gaggtagatg aaccttttat aaaagagctt ttaaaatcat taggacttga
    73921 aaataaacac gacgttttac caaatacatt atcaggtggt caacaacaaa gggtggcaat
    73981 agcaagagca ttagctacaa gaccagctat aatacttgct gatgaaccaa ctggaaacct
    74041 agattctaaa acatctgatg aggttatgag tatattaaaa tctatgtcta agaagtacag
    74101 tcaaactcta gttatgataa ctcatgatga cagtatagcc caaatggctg atagagttat
    74161 attcatagaa gatggcaggg tgtcaaaggt tggtgataaa aatgattaat actactaaaa
    74221 tagcaaaaag taatttaaag caaaataaat caaaaagtat tctaataata attactataa
    74281 tactttcaac cttaatgctt tcttctattg gaatttatat tgttgatgca ggagcatatc
    74341 aaaaagaaaa tactataaag tattcaggta attatcaagg tatattagca aatgtagacg
    74401 aaaaacaagc tgatatattg agtaatcatg cagatgttga attaactggt aaaatgaatg
    74461 gagtaggtgt tgaaaaactg gaagatgatt caaatatttc tctagcatac atgaatgaag
    74521 atgctttgaa attaaatagt tttgaattta tcaaaggaaa attgccatca aaagagaatg
    74581 aaattgtgtt agatagtgga gctttaaagg cacttggtta taaaaataaa gatttaggtg
    74641 aaaagataaa aatatcttat aatgactata aaagtgataa aaaaattgaa aaagagttca
    74701 ttataagtgg aatcttaaaa actagcgaaa tatctgaagc aggtaaatat tattatgcta
    74761 ttatatcaga atcatatatg agaaatacta gagatatgtc acaagaagat tttaatatat
    74821 atgtgaaatt aaatgataaa agtaatttat cgatagaaca agcaaaatca aaattaaata
    74881 agattgctaa tgatgtagga ttggacacta ttaatgtagc tgtaaatgaa aactatataa
    74941 atgctttaaa accagatatg gaaacaatta tgggtggagt atttgtaggg ttagtaattg
    75001 tattgtctag tattttagta atatacaata tattttatat ttcaatagtt acaaaggttc
    75061 aagaatttgg aaagcttaga gcaattggtg caactaaaaa acaagtaaaa aatatagtat
    75121 ttaaggaagg gttcatatta gccggaatag caataccaat aggaataatt ttaggctatg
    75181 tacttgcaaa tattataata aaatcattta tggatataga tgtaaaatca tcacgattac
    75241 cagttatatt atcggttgtg gtaataagct ttatatctgt tgttttatca cttttaaaac
    75301 caatgaaagt agcatcaaaa gtatccattg ttgacgcagt aagatataca ggaaataaaa
    75361 taagtaataa gagtaagaga aaaggatata aaaatataaa tctaaagaga ttatcacatg
    75421 ccaatttaga aagaaataaa aaacgtactt acatgacatt ggcatcactt atacttagtg
    75481 gaactatatt tataacagta tcaactgcct tagaaagttt tgatgctgag aaaatggcaa
    75541 gagaacactt tccttatgat atagaagtta gactatctgg ttatgaaatg aacagtgata
    75601 aaaatcctaa agataatttg aatattttac aaatggataa tcctctaagt aaagattttt
    75661 ttaatcaaat aaagaacatg gaaggaatta aaagaataga atctgcaaga agtgtaaaaa
    75721 ttggtatgga ggactatgat gttgaattta agtatgacct tttacaaagt ataaatgaaa
    75781 atgatgtaaa atcattaaac aagaatataa tagatggaaa aataaatctt gaaagacttc
    75841 aaactggaga tgaaatagta attactcatg ttgatacagc aaaagaaatg ggagtaaaag
    75901 caggagataa aataagatta actttatatg atggagataa aaagataaaa aaagaattta
    75961 aagttcaagc aatagctatg ggggttccaa gttttggtat agggaaggat tttattgata
    76021 gaactttgaa atacgattca actagtagct tgggaatata tacagaagaa ggaaagtatc
    76081 aagaaatcaa agatagtatc aagaagattg ctaaaaataa tggattttta gagactgatt
    76141 ttatagatag tagaattgag tcaaataagg ctactatttc atttataaag ataatgggat
    76201 acacgctaac aggcataata ggtgtgattg gatttatgaa tcttgtcaac acaatgataa
    76261 ctagcatagt tactagaaaa aaagaacttg gtatgcttca agctattggt cttactaata
    76321 aacaattagt gaaaatgctt aattcagagg caatgtatta cacttctgga atgatgatag
    76381 gaagtattct atttggaggt atattagggt atattgctgt tatatttcta aaaaagactg
    76441 gattatctta tgcaacatat tctttgccaa tagtaccaat cttgttgatg attgtgtgta
    76501 ttcttatagc tcaatttata acaacttatt tgataggacg aagttttaat aaagaatctc
    76561 ttattgatag agtaagatac agtgaataaa atacaaatat ttatggttag tttaactagc
    76621 aaaaaacata taaaaaaata tagttaaaga gattcataat taaataggtt aaagcatagt
    76681 acagagcaaa caatttaagc agatgtttgc tctgtatttt attatgtaat caataatata
    76741 tctaatatac tgatattatt catgttagaa aatgtaccgg tacaattcta aaaaagtata
    76801 aaattgtacc atataaaatg aaaattttgt ataataatcg tatagaaaat aaataggagc
    76861 tgatatatat gaataagaag attaattatg caccaggacc aactgaaact agggaaaatg
    76921 taagattagc aagagcagaa aaaacaacaa atccagatat agatattgat tttgttgaat
    76981 tttataaaaa gacatgcgag aagtttggta atataattgg aacaaaaaac gatgtttaca
    77041 tattgagtgg tgaaggaata ttaggtcttg aagcagcatg tgcatcactt acagaaaaag
    77101 gagatagagt acttgtaatt gacaatggta tatatggaga aggttttaaa gattttgtaa
    77161 caatgtatgg tggggagtat gtgctttttt caagtgaata tactaaaagt atagatattg
    77221 atgaattgaa agcattttta gatgaggata gtaattttaa atatgcaaca gtagtgcatt
    77281 gtgatactcc aactggcgta ttaaatgatg taagcaaaat atgtccatta cttaaagaat
    77341 atggaatatt aactgtagtt gattctgtag caggtatggt aggagaaaga ttaagtgtag
    77401 atgaatctaa aatagatata atattaggtg gttcacaaaa agctatttct gcaccagcag
    77461 gacttactat agtcggaata agtcaagatg caaaaaattg tataaaaaat agaaaaactg
    77521 atgtaatagg tttttattgt aatttaaata tatgggaagg ctattatgaa aaaaaatact
    77581 tcccttatac aatgccaata agtgacataa tggggcttga taaagcactt gataatatat
    77641 tagaagaagg aatagaaaat gtattaaata gacatgaaaa gatagcttat agtgttagaa
    77701 aatctattga ggaatatggt ctagaactat ttttagaaga aggatattct aatacagtca
    77761 cagctataaa aattcctgaa agtataggag ctttagaact tactgattat atgcttaaaa
    77821 attataatac acttgttgca acatcactaa atcaatatat ggatactatt ttaagaatag
    77881 gtcatatggg agagaatgca aatctaaata aaatagaaca tgtactaaat gttttggata
    77941 aaagtttaag tgcattagga ttcaaaggaa atggaaattt gttaaattta tttaataagt
    78001 attattttta atagataggg ggatatagta tggaagttac agctaagcaa aaatttacaa
    78061 cgaaagacat ggtggaaacc tcactattaa tagcattagt atttattgca actaaattta
    78121 taaacataag attaccaata tctataaatg gtgggcttgt gcatttagga actgcaatgt
    78181 tgttcatatc agcaatagta tttggaagta aaaaaggtgc tttatcagga gctattggta
    78241 tgtcactttt tgatttgata tctgggtgga ctttatgggc accgtttacc tttatagtta
    78301 gaggagttat gggttattta cttggaaaga ttgcatgggc aaatggtaat aatgggaata
    78361 attttttaat caatgtaata ggaatatgtg tttcatcaat ttggatgcta tttggatatt
    78421 atgtaacaga agttatactt tatggtaatt ttatagtacc tcttacttca ataccaggta
    78481 atttaatgca agtattgata ggtcttataa tagcgcttcc tatttctaag gtattgaaaa
    78541 aatgtataaa ataaatataa agtgaactaa aatttatgat agcataaatt atactgtata
    78601 atattaggat ggagtacata attaaaaaat tttagtatag aggttagttc acaatgttat
    78661 cagttacaag atattcaatc aaaaatgttc gtttaaagcc gtgggtaaag tttatttggt
    78721 attttgagac aaaatcaaat atactgttaa ataataagtt acttccgaca gacagtatag
    78781 atattattct caatctttct gatgttatgg aatataaaat tgaaaatcaa gactatattg
    78841 ctagtaatat tcattttaat ggaataaggg ataaacatgg atttattatt caacatggaa
    78901 atatacgtgt tatagggatt tctttttatc catttggtct ctatccattt ttaaagatac
    78961 caatttcaga gtttaacaga caaattgttg acctagaagc agtatcaaaa ctatttgcaa
    79021 aaaaattaga agagtcatta aatccaacaa aagcaataga aaaagttgtt ttatgtttag
    79081 aagaagtatt attatccata ttagaagaag atttaatttc aaataaatat gtaaagcttc
    79141 taaattcatt tatatatgtt aatagatata gcaatataaa agcattttgt gatgatacaa
    79201 atataaatat taaaacattg gaaagaatct gtttaaaata tacagggtat acacctaaga
    79261 ttttaaagag aatttacaga tttaaaatgg caagcaatca acttatttat aattataaag
    79321 atgatgaact ttttgatttt atttatgaaa atgagtacta tgaccaagca cactttataa
    79381 aagaatttaa aaaattttca gggacgtcac caattaaatt tagtggtgag aataagacga
    79441 ttaaagaaaa tataaagtac agctatttat aattatactg tcgatttttt acaatacctc
    79501 caatttattt tttgatatga tataggaaaa taaattggag gttttacata tgaaaattat
    79561 tacagaaata gttgagttta atgtggaaga aaatttatca aaagaagagt ttatagaaat
    79621 tgtaaatgac ttagaattaa aatttcattc tattcaatct ggttttattg atactgagct
    79681 tttatatgat gaaaagtctc aaaagtggat tatgatacaa cattgggaat ctatagaaga
    79741 cctcaagagt gtttctagta aaatgtttaa agattcttca actgagaaat ttagaaaagc
    79801 tttaaagaat caaactgtta agatgaatat aataccacaa attaaaagtt ggaaattata
    79861 gaactgaatg taaaagatag ttaaatagta tcaaactaaa ttagccaaat aacattttgt
    79921 atttaaattg ttatttggct tttagtgttt attttaatat gagtgttata tactagaaaa
    79981 accaacaaac tgttagagtg tggattatca taatgtcata ttcgggagct aaaaggctta
    80041 atactgattt gccaattggt caatccatgc atgtccatct ggatatgctg ttattaaagc
    80101 atttacaagc caatcccttt gctcttgtga taatagtggg actgttacat cgaagtcttt
    80161 ttgataacca agcctatcta tgtatattga tttgcaaaac aaaaccactt cgggagccat
    80221 atatgggata ttatctgatg ttatcagtct ggccttatcc atatctctta taattctttg
    80281 attttgggaa aaaagaaatt ttccatcttt ctgtggatta tatatcaatt caataaaatc
    80341 gaactgtaac tgttcgtcac actgtatatt cattttatag ttatcatcct cgactttttt
    80401 taattcaata aatgagcaat caggcttaat cgcaaaaaca caaatttgct ctatatgttg
    80461 cttgttaagg tcgataatag gtcgtaataa ataattaccc aagggctcat atatatccca
    80521 tccttgatta agcatatact gaatgctctt ttctttatct gtgtcagaaa tccatatgtc
    80581 aatatcactg tgtgggcgaa tatgcatatt cgcaaataat tctagggcat atccaccaca
    80641 tattgaatat gaaaagccac aatcattaaa aaagtttaca caatctttaa ttagtttgtt
    80701 catagcaacc tccttttgca tgtactgaaa taaattaaat tttttaaaat accaactaaa
    80761 tgtttgtttt gtgtaaatat aaaactgccg atattaaggc agttttatat ttactattta
    80821 gaaaatttat taacaaattt ttgatattca cacattatct tatcattcat aaaagaaata
    80881 cccataaaag cagcttgctc accaaacaaa gtaaaacgtt ctatcatctg ttgtggatta
    80941 cctggataaa ctgttggaat acaccatgtg tttagaagaa aaccaaacat ttgagcagca
    81001 atctctggat ttttaacttc catagaatta tcttgatttc cttcttcaat caatgctttt
    81061 atccaaggca caatatcatt tataatctca tcaaactgcg tagctaaata cttaggatta
    81121 cgcaatagtg atgatgacat taaaaaaatg tcttgtttat tgtgctgttc ataagtatga
    81181 agcaacctat attgtaattt ttctaatgcg gtctttcctt catcattttt tacctcatac
    81241 ccataaaatc catcattata caaccgactt gtgattgcct taattatttc gtcttttgat
    81301 ttaaagtgat gataaatagc acctcttgaa aggccatcta aattatctac aatgtcttga
    81361 atcgttgtct gctcataccc tttttctaag aataacttat gtgaaatatc aagtattttt
    81421 tgtatagtat tatcaggttc tttttttctt cccaaaaaac tcactcctcg aaacaatcat
    81481 ttggtatgtt tatcttagca aatacataat gatttgtcaa tgtgtctttt tagcatgttg
    81541 aacaggtata ttgccatgct ttcattattt tatttttttg ccttatactg gactatattt
    81601 gcagtttcct aatatatttg gctcatattt aaataccatt atctaaaagc actattgctg
    81661 tacgagaggc aataggcatt ttagaagaag gaggagttga gctaaagtat acatcataat
    81721 ctcttaagtt ttcttttttt gtgtttcctc caaactctac catatcagta tttaatatcg
    81781 ttttgtagtt tgtattttga aactttgaaa tatcaactga ttgtattaga ttagggtgga
    81841 aattaaatat aaataaatat ttgcccttac tgtacaccaa aatcttttta tcattatcca
    81901 tatgtataag ttcatgacta ttttggataa aaatatcact gtattttgta agttcgagca
    81961 tagatttatc aaaatttaat aattgtttat actttaagtt gttatcttct gaaaggctcc
    82021 attgtcttct ggcatactta tagctccaat tgttgccttc tcgtggaaaa tcaatccact
    82081 caggatgtcc aaattcattt cccataaaat ttagatatcc ttcacctgct agagaaaaag
    82141 ttattaattt aattaattta ataagagata ttgctctatt gataacatgg ttatttgagt
    82201 ttatttccat attccagtac atttccttgt cagctagcca aaaaataatt gttttatcgc
    82261 caactaatgc ttggtcatgg gattcacaat atcctatatt tttttctcca ggtcgtctag
    82321 tagtaagttc ataccacatt ttgcccaaat cccagtcttc atcagataag ttagagatag
    82381 tttttatcca aaaatcaggt actcccattg cgagtctata gtcaaatcca attccgccgt
    82441 cttttatagg gatacacata ccaggcattc cactcatatc ttctgcaata cttatcgaat
    82501 taggtttaat ttctttcatt aattcatttg caaattggag atatgttata gcttcaatat
    82561 ctgtattcat actaaaatat ttttcataac tatcaaatga aactccaaga ccatggttat
    82621 gatataacat tgaagttaca ccatcaaacc taaagccatc aaaatggtac tcatttaacc
    82681 aaaattttat atttgaaagc aaaaaatgta ttacttcagg tttaccatag ttaaaaagtt
    82741 ttgtacccca agcaggatga tttccctttg aacctgagtg gaaaaattga tgttcacttc
    82801 catcaaactc atttattcct tctaaagtat tctttacagc atgagaatga actaaatcta
    82861 ataaaacagc aatccccatt gaatgagcag tgtttatgag gttttttaag tcttcaggag
    82921 taccaaacct agatgagatt gcataaaagt ttgaaacttg gtatccaaaa gatgcataat
    82981 atggatgttc cataatagcc ataagctgaa tggtattgta tccagctttt tttatcttag
    83041 gaagtatttt ttcagtaaat tcattataag ttccaataga ttcgctttca gtagacatac
    83101 ctatatgaca ttcatagatt agtggagaag ttatgttttt taagtcaaaa tcattgtcag
    83161 tccagataaa tggagttttt ggttgccata tttgtccatt aaatccacca aaatcttttt
    83221 gaattactct ttttatatat aatggtatac ggtcaaatgt ttttccattt gcagtaactt
    83281 gtacctttac ctctgatttg tgaggtaagc tattttgacc aggaataaat atttcccaat
    83341 taccagaccc aatttttctt agaggatgag attttctatt ccaattatta aagtcaccaa
    83401 ttagtgacaa actatctgca tttggagccc attccctata gaagaatcca tcatttgtct
    83461 gatgaaatcc atagtaaaga tgagcatttg caaaagaact aaaatcttta tagtttttca
    83521 atgtttttga tttcatatcc tcataatgtt tcattcgctt ttttatatca gattcaaatg
    83581 gttgtaggta tacatcaata tctaaaattt taaatctttt ttgacttttc attgtatttc
    83641 tcctccataa taaatattac atctaaaaaa taatatttat ctcatactat cttctctgta
    83701 taattgatat atattatata atcctaataa aaagcttaag ccaccaatga ttaatttcat
    83761 aatttacctc cctagtattt atacttatat atcgtattca tcaaaattta aaagtttgtt
    83821 taaaactctt ttaataatat cataatcaaa gcctttatag gaaagatgtt gagaaatttt
    83881 ttgatatatt ttctttttat cttctttctt tactctttca tacctttttt ttgctagata
    83941 catagcattt tcaaattcag tgtccttgtc taattcagat actgcttcat tgattgtact
    84001 tctattgata cctttattat ataaattctg cttaattctg tttttgccac atttatttag
    84061 gttaacattt gtgttaacaa ttttttgagc taatacactg tcatttacga gattataact
    84121 tttaagaaaa tctatgaccc tctcaattat attttcatca aattctgatg atagtttttc
    84181 ttttaatttt ttttcagatt ggtcagcatg agataaaata tttaatgctt tatttttagc
    84241 ttttatatac atttcatcat ctaaaatagg ttttaattct tcttcattta tttcattccc
    84301 tttttttaaa ttaaatgtat aaaccagttc tttaaatata gcaataaaaa atttatcatc
    84361 tacataaata ttaactctat catcatttct tttttgttgt tctatttttg taattatacc
    84421 cataagtcct ccttttttat atgtaattat attaacaaaa gcaactaata aaatttaaca
    84481 aaaaacttat atttgtatgt tatattttat caaaattaag acaaaatagt aaaaagttat
    84541 ttttattaaa aagtaaagca gaattatgtt aaataattat tttttaaagt gttttttagc
    84601 atataaatat aattatatac ccaaaaaaac aaattataag ctttaagaaa taaaaaataa
    84661 tggtacaata gtattataac attaaaagga gacaaaatat gagaagtgaa aatctagtta
    84721 agatggcaga gttgaaaaat actgaaaaac tagagaaatt taatcgccat aaaggcaaaa
    84781 tcaaaatagg tatattggga ggtacttttg accctataca ctatgctcat ttagcaacag
    84841 cagaatttat tagagacaag tatgacattg acaaaataat ctttatacca tcaggaaatc
    84901 caccacataa attatgtatc actacagata agtatgatag atataatatg acacttctag
    84961 caactgaaag caacgaagat tttttagttt caaaagtaga aatcgaaaga aagaaaagga
    85021 cttatacaat agatacatta aaatacttaa agaaaaaata caaaaatgca gacatttatt
    85081 ttataacagg tgcagatgca atttgtagtg ttgaagagtg gaaagatgta aagaaaaact
    85141 ttgagttagc tacttttata gccgcaacta gaccaggaat tagtttgtta aggtcacaag
    85201 agactataga aaaactaact aagaagtata atgctgacat tataacagtt tatgttccat
    85261 cactggatat atcgtccaca tatataaggg aacagctaaa tgaaggcaag tcaatacgtt
    85321 acttagtacc cgaaaatgta gaaaattatt tatatgaaaa taaactatat caatatggag
    85381 atgattaaat gaacttagaa aatattaacc aaagactaaa tcaaatgcta ccagtgggga
    85441 ggcttagcca ttcaaaaaat gttgcaaaat gtgctgaaaa attatgtgag atttatggat
    85501 gtgacaaaga aaaagcttac ttagcaggaa tgattcatga ttgtgcaaag tatttaagtg
    85561 acaaggaaat agaggattat gtaaataagt atgaaatata tttagaccca atagaggatg
    85621 gaaatcgttc cttgtctcat agtgtaattg gggcgtacat atgcgagtat gaatttgaag
    85681 tggaagatga agatattata aatgcaatca aatatcatac aacagggaga gaggacatgt
    85741 ctcttttaga aaaaataatt tacatagctg atttaattga agaaggaaga aaattcccag
    85801 ttgtagatac attaagagaa ttagcatatg gagggaagct tgatgaagca cttttaactt
    85861 cttttaataa tactttaatg tttgtcatca ataaaaaaga agagatacat ccaagaacag
    85921 ttatggcaag aaactatcta attaaagaaa agttattata aaaaagctat ataaaggcaa
    85981 acatattaat aaatttaaat ttgactatgt tacaaaatcg tattaatatg ttacaataac
    86041 taagtgtatt ttaattagga aagtgaggaa tttttatatg acagtggaac aaatgacaaa
    86101 aatagcatat gatgccatag aagataaact gggtcaagat acagttataa taaatatagg
    86161 aaaagtttct agtttgtgtg attattttat tattactaca gcatcttctc agagacaggt
    86221 aaaagctatt gctgacaatg tggaagatga attagcaaaa ctaggattag agccaagagg
    86281 taaagaagga caaggaactc aaacttgggt actccttgat tatggagaca taatggttca
    86341 tgtatttaat gaggaaaata gagggtttta taatttagaa aaattatgga aagatgcacc
    86401 ttatatagat attgacacat tagcataaac atgataatat atgttattat aattagaaaa
    86461 tttcaaaaat tatattaaat tgaatagact agagcagtaa aagattatat tttttcagag
    86521 agttagtgga aggtgagaac taatattata taactttgaa cttactagat taaaatctat
    86581 tctccatggc tggattaaaa gctatctaag agagtctata tatgtagtag gctaattagg
    86641 gtggtaccgc gaagatttat cctcgtccct aaacgtaagt ttagtgacga ggatttttta
    86701 ttttcaaaga attatttgga aattataagt aaataatact aaataaggta gttatacaca
    86761 attaaaaata ggaggcaaaa tatgagcgta tataatttta aagaagtaga atcgaaatgg
    86821 caaaaaatct ggaaagataa taatcagtat aaaatggata ctgcacaaac tgaaaaacct
    86881 aattattaca cattagaaat gttcccttat ccatctggaa aaatacacat gggacatgtt
    86941 agaaattatt ctataggtga tgttgtcgca agattcaaaa aaatggaagg atataatgta
    87001 cttcatccaa tgggatggga ttcttttgga ttaccagctg aaaatgcagc tataaaacat
    87061 ggaatacatc cacataaatg gacaatggaa aatatagaag aaatgaaaga gcaattaaat
    87121 ttattaggta ttagttatga ttgggataaa gaagttgcaa cttcaacgcc agaatactat
    87181 agatttacac aagaaatatt tttgaagttt ttagagcatg ggcttgcata taagaaaaaa
    87241 tcatatgtta actggtgtcc ttcttgtgag actgttcttg caaatgagca agttgttcaa
    87301 ggagcatgtg agagatgtaa agcaacagta ttaaagaaag atttagaaca atggtatttt
    87361 aagactactg aatttgcaga agaattactt aatgacttag atatattaga tggatggcca
    87421 gaaaaagtta aaacaatgca aaaaaattgg ataggtaaaa gtacaggagc agatttagtt
    87481 tttgatatag atggaactga taaatctatg acagtattta caactagacc agacacaact
    87541 tatggagtta cttatatggt acttgctcca gagcatgaat tagttaaaga attggttgca
    87601 gggactgaat atgaagcaga tgttgaagct tttgttcaaa aaatgcatac tatgacagaa
    87661 atagaaagaa cagcagctga tgtagaaaaa gaaggaatgt ttataggtag atatgttata
    87721 aatcctttaa atggcaagaa agttcctcta tggatagcta actatgtatt agttgagtat
    87781 ggaacaggtg ctataatggc agttccagca catgatgaaa gagatagaga ttttgctgaa
    87841 aaatataatt tagacataat tgatgtaata acagaagata acaaaatgat aaattcagaa
    87901 gaatttaatg gattagatgc ttcagaagga tttgaaggaa taatcgataa gttagaaaaa
    87961 gaaggtagag gaaagagaac aattaattat agacttagag actggttagt ttcaagacaa
    88021 agatactggg gttgtcctat acctgtggtt tattgtgatg aatgtggaat agttccagtt
    88081 aaaaaggaag atttaccagt tcttttacca acagatgttg aatttactgg aaaaggggaa
    88141 tctccactta cgacttcaaa gcaatttatg tcaacaactt gtcctcactg tggaaaacca
    88201 gctagaaggg aagttgatac tatggataca ttcgttgatt cttcttggta tttcttaaga
    88261 tatgtggata gcaataatga aaatgaacca tttagtaagg aattagttaa tagatggcat
    88321 ccagtagacc aatatatagg tggagtagaa catgctataa tgcatttact ttatgcaaga
    88381 tggtttgtaa aggcatttaa gagtatggga atggtagact tcaatgagcc atttaaaaac
    88441 ttacttactc aaggaatggt acttatggat ggttctaaaa tgagtaagtc taaagggaat
    88501 acagtatctc ctatggatat aatagatgag tatggagcag atactgcaag acttttcgta
    88561 ttatttgcag caccaccaga aagagatttg gactggtcag agcaaggtgt tgatggatgc
    88621 tttagattct taaatagggt ttatagattg gttgacgagt tagcagatgt ggttaaaaag
    88681 gatgtagagt ttggagaatt aaattcccaa gataaggata tgagatatac tatacactct
    88741 acacttaaaa aagttactgc tgatttaagt gaaaaattcg gatttaatac tgctatatca
    88801 gctcttatgg aattaataaa tgatatgtat aaatataaag agttagataa tataaacgaa
    88861 gcagttataa aagaaggtgt acaaactata gtaactataa ttgcaccatt tgcccctcat
    88921 ttaggtgaag aactatggac tatgataggt aaagaaggaa gtgtatttga catagactgg
    88981 cctaaatatg acgaaaaagc tttagtaaaa gatgaaatag aagttgttgt acaagttaat
    89041 ggaaaagtta gaggaaaatt aactgttaac tcaaatatat ctaaagatga gatggaaaag
    89101 gtagctttag aagatgaaaa aataaaagga ttagttgaag gtaaaactat agttaaagtt
    89161 gtagctgtac ctaaaaaact agtaaatata gttgttaaat aactcaaaaa tatgaacaaa
    89221 aatataaatt tataaaataa acgaggctgt ctcaaaatag agataagcct tttttcattg
    89281 ttgaaattat aaaattgttg aaattataaa aatagatttg attttataca aaaaaatgat
    89341 taaagaacta aaaagttcat tcttatatac cctagttgtt gttttaaata ttattataat
    89401 taatgttaaa tcgagttaat gtattaagtg gtatgtaaat cattcagttt ccaaagtgtt
    89461 gttcatcaag gaactgctct aagcttaaac gaaaaaaata taattattgt attttgaaat
    89521 ttttttctat ataatgaaaa caggcaaaaa aggtgcgtat ctatgcttta tatgaaacac
    89581 ccagacaacg aaattcagat tcatataata gctaccatgt ttctaaaaag gaacttgtaa
    89641 aaaagatagc gtttcaactt cccagttgat taaaattatc agcaggaaaa caagtatggt
    89701 cagcagtggt attctaatgg gtgttgtcga tatatccaag ttgggattgt ctgaggatgt
    89761 tatcaaataa cttgtgatag gtgcagtaga tgtggagatt cctgatacgg atttattctc
    89821 aggggatggt tgcttcggga gatatggagc gtaaccagtt tattgatatg gtaaccattt
    89881 tttgtctaat ttgatgaaag aatcccaaga ataccataca gaagtaagac aggaattaac
    89941 tggtggtata aactgataaa ggcaaattta aaaattttga taggatgatt ttaagattta
    90001 tcttctattt tgtgttttag aaataattga aatgttatga ggaggtatgt acaaatggag
    90061 actgtaacaa ataatcaatc aggtgtagaa attcaactca gtctgtttga agctatcaaa
    90121 gatttattgt taattaatcc tattttcttg ttgggaatta tcttgattgg tattttctta
    90181 gttgtaatat tcaagaaaaa tagtgatatt ccaaaggtaa aaacatctat tttatcactg
    90241 gcaatgtatt actacttatg tttaacacta tcgcatattg ttggtatccc tacattcagt
    90301 gaatatataa gactgtcaca gttaggggaa acgttcttta atccaaacat aaatcttatt
    90361 ccttttagtg atggatttag tttgagtttt attttgaata ttttactttt tgtcccatta
    90421 ggttttttat gtccgcttat cagcaaaacc tttgaacgtt tgagaaatac attcttgatt
    90481 ggttttggat tatctctttt tatcgaaact attcagcttt ttacgttaca cagagcaacc
    90541 gatatagacg acttactcac gaatgtaatt ggaacaataa taggctattt ctgcttcaaa
    90601 ctgattgcta aattgcgaat tgtaaaacta cattcagatg atgactctat ggaacaggat
    90661 tacacagtat gtattccgat tgccattata atagttgccc ttatattagg attttttagt
    90721 taagttccaa atagctaatt tgggaattat ggaggtcatt aagtgaataa aattactttt
    90781 atatgtttag gtgtaaaaag tatggagaag tcaattaaat tttatagaga tggattagga
    90841 ttttagatta caaactttta gtttaccaag gagatagcaa agttgtgtgc caaagggtaa
    90901 ccatttggaa atccagacaa cataacagat agtacgttac cttttacagg agcatactat
    90961 ctgttatatt gtcaacatcc tattttatgg tttgtgtgta gtttcctgta aactgaacta
    91021 aataattaaa tagaagctat tagaattaat aataacagat agatattaat aagcataaac
    91081 aaatagtaaa atgtgtagat atagacgttt ttaagtgaaa ctattataaa ataattgact
    91141 gataatcaac tgacaaaacc tattttttta ggtttaactg acatttaact gacagtcagt
    91201 ttttactatt taaatagaag ttcgcttaga ttgtcggaag cttctttgtc catttcttta
    91261 agtacatgag aatatctatt catagttatt tttatatctg tatgacccaa tctttcagaa
    91321 acaactttca tattagttcc ccctaaaagc agcagagtgg cacttgtata tcttaaatca
    91381 tgtattctaa tcttttttaa attatttttt ttgtaaaatt gtgaaacgtt tttcttagtg
    91441 aagaaggtag aaacggattt aaattggtgt ttagacaaac taaattattt ctgttttcca
    91501 ggatacctta caattttaat ttgctttgtc ttagtttttt aattttcaat ttttcaatta
    91561 attcttttgg agctgataaa gctctttttg attttggtgt ttttggctct ttaaaagata
    91621 ttttgccatt agaatagaca agaatttgat taacatttat cagattgtta tctaagtcaa
    91681 catctgacca cctaagccca gtagcttctc ccattcttaa acctagaagt aacattaaaa
    91741 gaataggtat ttctatatta ttactaagta acttttctat tagcaataat acttcttttc
    91801 tattgtatat ttcatttgta gaatattttt ctttagaagg aagttttata aaatcacatg
    91861 aattttcttg tatttctctt aatctatatg cttcccttat tacagaactt agaaagctat
    91921 accttacttt agcactagta aaggtagaat tattaaagtt ataatttaca aaagcttgta
    91981 ctgaactagg atttacttct gtgagtttta gattcttaaa aagaggttct atgtaatttt
    92041 taacccaaga ttttgtattt gtaacagtat atggagacca attattttta ttcatgtcca
    92101 tgtatttata acatctttct acaaatgtca tatcttttgg agcaacaaac ttattattgt
    92161 ttatagtaga ttttatttca attaaatgtt tttcagcatc ctttttcttt tcataacttc
    92221 cataactttt ctgttttatc ttgccagttg tttcctctat gtactccaca tatacataga
    92281 atttttcccc tctttttctt ataaaagctg atttgatatt catatatgta cgctcccttt
    92341 ataagttagt tttataaaag aacagttgta ctactctaat tatgtcatta tctttttaat
    92401 tctttacagt tacattataa cacgtatttg tatacactta aattaacagg aagataaata
    92461 tcgttaaagg aggaaaagaa aatttaatgt agaattatta agatatatag tatttcatat
    92521 ataaaagggg gagatattgt gaaattaaag aaattattat cactagggtt agtgtcaatg
    92581 tttgttgctg gttttcctat atcagctaat gcacttgata aaattgataa aattcaagga
    92641 gcagataaat acgaaactgc tggtatcata gctgacaaac aaagttatac tactgcaata
    92701 cttataaatg cagatagtac aatggctgat gggctaagtg cgagtggact tgcaggagca
    92761 acaaatgcac caatcctttt gactaaaaag aataatatac ctaatgcaac tcttaaaaga
    92821 gtagaaaaag ctaaaaaggt atacataata ggaggagaaa gttccattga taaagcaaca
    92881 gaaacttttc taaaagataa aggaatagag actagaaggc ttcaaggtaa tgataggatt
    92941 aagacaagtt ataatgtagc aaaagaaata aattccatta ataaagtaaa taaagtaata
    93001 ttaactaacg ctttcaaagg tgagccagat gctatgagtg ctgcacctgt agcagttaga
    93061 gataaagcag ctatagtatt aactgatgga aaaagtgttc catttaatac aactggtata
    93121 gaaagttatg caataggtgg cacttcatca atgagtgata gtttagtaaa tgatactaat
    93181 tcaactcgat tgggtggagt agatagatat gatactaata aaaaaatagt aaataagttc
    93241 tataatggcg caaaagaatt ttatatagct agtggtactg atttagttta tgctttagtt
    93301 gcttcaccaa tggctaaaaa taatcctatt gtactagttg atattggaag taataaagat
    93361 atacttaaaa atgctgcaaa agtaaccggg ataggaaatc taagtgataa aattatgcta
    93421 gagtgtgaaa ataccatcaa taatattagt cttccatctt caaataaaaa tataatatgt
    93481 ggattaaaga ttgattttga ttcaaatcac ataatttggc aagataaagg aagttatctt
    93541 gaatgttatg atgataacct tgaatattat actgaaaaat ataaagaccc aacagttcct
    93601 ataaatatag aaaatacaag tacacaaaat ttagatgtaa caaaattaaa agtttatgga
    93661 gaagctaatt caacattata tatggggcaa tacgctaaaa taaaaatgga ttttaatagt
    93721 ttcggtgtat taaagccagg agaaaaatgt actatttatt tagatataat ttcattagat
    93781 ccatcaagaa gcatgacatt aacattttct tatgtaggtg ataaagaaaa ttataaatat
    93841 gaacaaggat tggcaagtag aatattattt tataacccgg atggagaaga tttttttgaa
    93901 tataaataac tagtgggtat gtaaatgtct cgatattgct catatgttga gttattatat
    93961 ttagtttcat atgaactata tggattttaa aattaaaaat acttaaaaac atttacttta
    94021 atagtaggtg tttttttgat taaaagaata ttattataat gtaaaaagta ataaataggt
    94081 aaaatatgta agaattatat gttataatat ttttagcaag aagatgtaat ctacaattta
    94141 tagagtggag ttcatgtatc aaaaaattat cctcccgacg ttaagaaggg aggtgaatat
    94201 acatggataa ttttttacaa ggcatactag caagtctatc tgctagctta atagtttata
    94261 tagctagcaa actatttaga aagcgtaaaa aaccactcaa agcggcaact aagagtggtt
    94321 gggaatttga tttaaaaatc agattccata aaactaagta atttctaaat tatgaactcc
    94381 actctacagc aaaatagatt gtagttcttc ttgcttttat tatatcacaa attggtacag
    94441 atattcaaaa ataatatttt tatgatataa taaagtcata gaaattttgc agtgttcgat
    94501 tttttgaaga aattaaggct taacagttga aatataaggc attgaggact tgtgataagt
    94561 gttatcaatt gcactactca tggttcactg caaatttgag agatttgtat atgtgtaggc
    94621 attggaaata ctcaatttat tttggggttt tatattaact atatggaatg taaatttcat
    94681 attccatgca ttctgcttac acttaataga aaagttttat attaactata tggaatgtaa
    94741 attatttcta gcgacttggt cggttgctcc atttagcttg ttttatatta actatatgga
    94801 atgtaaattt tttcaaatct gatatatcga ccttaaattt cgtgggtttt atattaacta
    94861 tatggaatgt aaatgatata aactttggga gttcagaaga aggattaaaa agttttatat
    94921 taactatatg gaatgtaaat tagagatgaa ctcagataga aaaacatgta gatgtgtgtt
    94981 ttatattaac tatatggaat gtaaattctt caacagttgt gttaccatct cctacacgca
    95041 caggttttat attaactata tggaatgtaa attgctacgt aaccagtttc accgctttca
    95101 gtatataacg ttttatatta actatatgga atgtaaattg tatccaaaaa attacaataa
    95161 tcatacgaac tgctaatata agcagtcaat atatgtgtac atttatctat tttatctcta
    95221 aatatataaa ttattatccc cctaaaaaac tttcataaaa acaaaaagaa caatatctct
    95281 ttggcaactg gctgacataa ctcataagat atttatataa gtcttagtct ctatagcttt
    95341 gcgtcactag atttctctag ttttgccgat ttagttttat tctataacta aataatacaa
    95401 tagaattagt tattattcaa taagattgtt tgaaaattga ataaatttat aggtatgaac
    95461 gtaatttcac acttaaaaaa cagactaaat acgtagaata tatagaaaaa tttacctgta
    95521 gtttttgtga taaaaagctc ctattattaa tttaagctag ataagtttga ggaagtgaca
    95581 taaattgaaa gaaggaatat attatgttga ataaaaaatt accagatgca gaattaaaaa
    95641 ttatgaaata catatagaat actggttata aaactgtaat atcaaaagat gttgcagatg
    95701 aaatagaaaa aacatatgct tggaagcata caactacaat tacactttta gctagattaa
    95761 ctaaaaaagg ttttttcata tcgcagagaa ttgggaaaca tgtacactat agagtattaa
    95821 taaaagagaa agaatatctc aaaatagagg gaaaaagaat ttttggaggt ctacataaca
    95881 atccattatc agaattaatt tcaaaattgc atgatggaga agaaataact gaagaaaaaa
    95941 taatagaaat aggaaattgg ataaaaagct ggaaagatga agattaataa ataaaaggta
    96001 gctactaata taagtgctac cttttttctt gtggataata ttggggataa gttgtggaaa
    96061 acttgtggat aaaatatttt gctgacattt aactgacata agtattagat tttgatttaa
    96121 aaatgttgaa atatcaataa ataattaaat agaagttatt agaattaaca atagattcct
    96181 ttttcaaaga aatctttgat ttcatcaagg ttatcagttt ttccaagtgc taagataagt
    96241 tttattctag ctttttgacc tggtaagtcc ccaccaaata tacaaccaag attttttaaa
    96301 tctctaccag aaccaaagta accataacta tcgaatactc tacctgaatg acatctagaa
    96361 actataacta caggaagtcc tttttctcta gcatattcaa ctccagaaag catttgagga
    96421 ggaatattac ctctacccat tgcctcaata actatacctt tataaccact atcaacagca
    96481 aatcttataa agtcagcatt ttctcctaca tatgctttaa ataaggcaac tttagattct
    96541 accttatcag tatctataat tgttctattt acaatatctc ttgtaaggac aagttcgttg
    96601 cagtcaatta ttcctaatgg gccactagtt agagatttaa atgtatttag agaaagagta
    96661 tttgttttag tagcttcaga agctaataat acttcattgt ttaaaactac aaggactcct
    96721 tttcccatag catctttgga tactgcagta caaactgatg cagataaatt acttgaacca
    96781 tcatatccaa gttcagaact acttctcata gcacctgtga ctattacagg tttgatgttg
    96841 tcaattgtaa ggtctagaaa ataagctgtt tcctctaaac tatctgtacc atgtgttatt
    96901 acaacacctg taatatcttt tcttgctaat aaatcattta cataattttt caattccatc
    96961 attctataag gtgttatgtg aggtcctgga atttcatcaa aattaaaaac ttcaacatct
    97021 gcaactttat caatgttggt aaccattgat agtatttgtt cacctgataa agttggtata
    97081 gctgctccga ctttatcatc tactgtcata gatatagttc caccagtaaa aactatggca
    97141 acttttttct taatactcat actattctct gcctttcata aataaaattt ataattccga
    97201 taggattata tcaaaaaaag tagttaaggt ctacataaac tcttttattc atataattta
    97261 gatatttcag tgtaatataa ttatttctta attttttgcc attcaacgat ataaccattt
    97321 aatatctctc ttatggcttt tcctatctta gtataagctt catcatatag atttgctaga
    97381 gatattctaa ttgaccattc aggaccatag aatccatttc cactaagtaa aactactgaa
    97441 tagtcattag ctaatttata aagaacatct actggagatg cagttttact tataaattta
    97501 aataagtctt ctccgtagtt taatttagcc cattcttcaa tatcaaattg agtgtaatat
    97561 gcagcattgt ttttgttttc attaattgga agctctaaag cttcaaataa tagtttttga
    97621 cgtctatggc agatactcat attgagtttt ttgtaggcat ctactttgtc aatcaatgca
    97681 aaagcagaga aaaacgccat ttgtacttgc tgtggagtag aaagaccagc agtatggttg
    97741 agagcaacaa gtctgctatc agcaacaact ctttccataa atgaaaggct agaagggtta
    97801 agactcatat cactgtaacg cttatctact gattttttta attctccagt taaatcattt
    97861 attttcttat caaaaacatt tttcttatga agggcaaatg taccaagtct ccatcctgta
    97921 actccaaaat attttgaata agaatatact ccaacagtgt tgtaaggtag ttttgacatt
    97981 aaggatgaaa aatcttctac aaaagttcca tatacatcat ctgatattat cattaaatct
    98041 ttattataat tttcaattac atctattaga ttattacaag atgtttcatc catagctata
    98101 gaagcaggat tattaggatt aacaacgaat aaagctttaa tagatttgtc acgaagtttc
    98161 tctaattctt tttttgtata ttgccatgta tgagcacctt tttcatcaac ttcattagca
    98221 tttatattta ccactttaaa gtcgtaacga ggaaggttag gtatttcaag ataaggtgta
    98281 aatattggag tcattaaggc tatggtatct ccttttttta gaagttcatt tgccattaat
    98341 gaatcaaata tatagcacat agcagctgta gcaccttcaa cagcaaaaat ttctacatca
    98401 ccatatttac ctgatatatc atatttcatt tcttgaacta ggtaatcgtg tactattttt
    98461 tccatatgag gtaacattct atctggaagt ggatagttat caccaataat tccatcagct
    98521 agttcatgaa caaattcatc tccatcaaat ccaagttcat ttataccaaa gtttataata
    98581 tctctagcta aatatgctcc aggcatatct atattttcat ttataaattt aaaaaatctt
    98641 tctttaatac cctttttttg aggcattcca gccaaatgac ctaaatccca attagaacga
    98701 gtttcagtaa tagcgaaatg accaaaagta aaaaaggctt ctctagcagt tgaacaagtc
    98761 cagtttggat ttccacgacc tgcatcaagt aattctctgt tattttcttt tgcagtgtat
    98821 tttgcaatat ctattaattt gtccttaaat tcaaaagggc ttatttttcc atatatgttt
    98881 ttgatttctt tataagtatg atttttcatg ttaaattcct ccttatgtaa taagtttcac
    98941 atttttataa taaaataaac aagttgcaaa aatgattata ctttaattat aataggttta
    99001 tagaaaaagt
//
LOCUS       DAYAOO010000003        88625 bp    DNA     linear   BCT 12-OCT-2024
DEFINITION  TPA_asm: Clostridioides difficile isolate ST8-SSI-h139-18
            SAMN40601845-rid21577343.denovo.003, whole genome shotgun sequence.
ACCESSION   DAYAOO010000003 DAYAOO010000000
VERSION     DAYAOO010000003.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN40601845
            Sequence Read Archive: SRR28438827
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 88625)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 88625)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-MAY-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-MAY-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002157583.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002157583.1
            Genome Coverage       :: 163x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/11/2024 16:19:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 4,038
            CDSs (total)                      :: 3,963
            Genes (coding)                    :: 3,930
            CDSs (with protein)               :: 3,930
            Genes (RNA)                       :: 75
            rRNAs                             :: 6, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 60
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 33
            CDSs (without protein)            :: 33
            Pseudo Genes (ambiguous residues) :: 0 of 33
            Pseudo Genes (frameshifted)       :: 7 of 33
            Pseudo Genes (incomplete)         :: 25 of 33
            Pseudo Genes (internal stop)      :: 11 of 33
            Pseudo Genes (multiple problems)  :: 8 of 33
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..88625
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN40601845-rid21577343.denovo.003"
                     /isolate="ST8-SSI-h139-18"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Denmark"
                     /collection_date="2018"
                     /collected_by="Statens Serum Institute"
     gene            63..1607
                     /locus_tag="ACGI5H_000247"
     CDS             63..1607
                     /locus_tag="ACGI5H_000247"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889520.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative bifunctional diguanylate
                     cyclase/phosphodiesterase"
                     /protein_id="HFG9695980.1"
                     /translation="MRNLQKKLMFFLFICIILQITYTTPVYSLCKLYKNNSINNFESI
                     VSNNQLISKHAIQIILIMAIICVILIFYIIYDKLNFKIKLQRIAYTDNLTGANTIDKF
                     VIDANKILCKNTQVKYALLYIDIDKFKYINDLFGYEVGNEILRNLTKIIKSNIFEEEM
                     FARISADNFIIIMKYIEEEDITKRLKTIFEELDLFNNNQEEKYKLVLSCGIYFILPED
                     RDINSIIDRANIPHKMAKGGHKSSYAFYDNKIHDQEIKEKEMENTMFSSLENKEFIIY
                     LQPKIELNTGEIQGSEALVRWKRPDKGLIPPNEFIPFFERNGFVINLDLYVLEEVCIY
                     LRKWIDAGINPVTVSVNVSRIHLYCNNFIETYKNIIDKYNIPAKYIELELTESIIFDN
                     FDILIDIMNNLKKIGFLISMDDFGSGYSSLNMLKEIPMDILKLDQKFIMETYNSKRSK
                     IIVTKVIEMAKELGMKVISEGVETEEQFKLLKEVKCDMAQGYLFGKPMPIEEFEHLIV
                     SNLVRG"
     gene            1783..2151
                     /locus_tag="ACGI5H_000248"
     CDS             1783..2151
                     /locus_tag="ACGI5H_000248"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436369.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HFG9695981.1"
                     /translation="MEWELDNNKPIYIQLVEHLKLKIISGEIKIGSKLETVRALAEDA
                     EVNPNTMQKALTELERQGLVYSQRTKGRFVTDDKEKIKAMKEEIANVEINTLKVTLEK
                     LGYDRDEMLKLITENLKGEL"
     gene            2153..2878
                     /locus_tag="ACGI5H_000249"
     CDS             2153..2878
                     /locus_tag="ACGI5H_000249"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436372.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HFG9695982.1"
                     /translation="MDKNISNVSQDGIVEFKGVNKSYGTKNVLKNIDLNIPKGKIVGL
                     LGPNGSGKSTMIKLMNGLLQPDNGEIMINGMKPSIDTKKIVSYLPERTYLNDWMKVSD
                     LLKFFYDFYSDFDVRRANEMIKSLDIDVNEKLKTMSKGTKEKVQLILVMSRNASIYIL
                     DEPIGGVDPAARSYILKTILKNYSEDSTLLIATHLISEIENICDEIIFISKGEIVLQG
                     DVEAIREEKGKSIDALFREEFKC"
     gene            2872..3636
                     /locus_tag="ACGI5H_000250"
     CDS             2872..3636
                     /locus_tag="ACGI5H_000250"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430055.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HFG9695983.1"
                     /translation="MLGKLLKYELKASGRIFIPLYIAILIVAVFNGIFMNTNILQVQG
                     IGILVLTSLFMALGVLTIVVTIQRFRKNLLGDEGYLMFTLPVSTSSLILSKCITALIY
                     AVLSFIVAVFTFGVLMLFGTSGILLPEILDLFNTSFKWISENFLDILLLVVVMFISYS
                     SFILLLYTSISMGQLPKFNKHRNIVAFASFIAINIVISIVGDAVGSILPNEDTNMVYH
                     LYQSPSFMLAILGSLVVAIALFFATKFILDKKLNLE"
     gene            3858..5108
                     /locus_tag="ACGI5H_000251"
     CDS             3858..5108
                     /locus_tag="ACGI5H_000251"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902660.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HFG9695984.1"
                     /translation="MKSYTKAKWSVWGIITFSFVLVLFLRMSTAVVSDNLANELGFNS
                     IQISNIASFCLYAYAFMQIPAGILIDKYGARKISSLGIIMASLGSILFGLIQSIELAY
                     ISRVIVGAGTSVILLCILKIQGRWFNKSEFASATAKFSFVGNLGGVLATFPLVFLSEL
                     VGWRNSFLLIGIIGVVIGCFMYIIVRDTPKEYGFNVDTEPYEKSEKVNIVDGIKSVIK
                     NKSTWYNSMIMFSFVGLTSAFISLWGVRYIMDVYGVSKSFSAFIVSFFTYGFIFGSII
                     MDFVFAKIRSSKFNIIKFGAMIDLFIWIVIVVVYQVKPPIIVLPISFFIMGCIVMSHL
                     QVFNDAKYKNKEIYSGLATSVINTFEFIGSGIINLIIAISLQVNSYNIVDGYKKGFVV
                     FIVLSIITIVSSHIGVKNDDFKAI"
     gene            5299..6183
                     /locus_tag="ACGI5H_000252"
     CDS             5299..6183
                     /locus_tag="ACGI5H_000252"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="mechanosensitive ion channel domain-containing
                     protein"
                     /protein_id="HFG9695985.1"
                     /translation="MDTTKIDDISKLDLNNLDINKMDMGGIMESLLEWATTSGVKLII
                     GILILSIGFKIIKKFVNHVMLLLSKRDIDLTLRKFLKSLLLSVLKVAVIIIVLEYWGM
                     SLSSFAAVIASAGVAIGLALQGSLSNFAGGFIILLIRPFKVGDYVEAAGHGGTVEQIG
                     LFYTQLVTPDNKQILIPNGSVSNDSLINYSAKNTRRVDLTFSVGYEDDILHVRRVLKD
                     IVNNHKLIINEPEPFIGVVEHGDNAIKFATRVWCKTEDYWTIYLDLLEEVKVRFDEEG
                     ITIPYPKMDLTVKELNKI"
     gene            6545..7162
                     /locus_tag="ACGI5H_000253"
     CDS             6545..7162
                     /locus_tag="ACGI5H_000253"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PepSY domain-containing protein"
                     /protein_id="HFG9695986.1"
                     /translation="MCKKTYLLVVSMLIAGLLTACSGSPTKDSGQAQDNTKKEANASN
                     NALKDEKNNENLMEQDFKVPYTDAINIFKDKYKDADIVDLSLERDLNKFVYTVEGVDD
                     NNEYKMKIDANTKDVLEDKTEKLDSEDLNGVARKEKLDLNDIMTPQQAMEIALKEQNG
                     IVKEWSLDKDLDVTFYKIRIDKDKNEYDIKVDSKKGTVLKVEKED"
     gene            7270..9801
                     /locus_tag="ACGI5H_000254"
     CDS             7270..9801
                     /locus_tag="ACGI5H_000254"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420250.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-dependent oxidoreductase"
                     /protein_id="HFG9695987.1"
                     /translation="MSLKSLKIKENLYWVGSLDPDLRVFDIIMYTPYGTTYNSYVLKG
                     TEKTVLFETVKDKHFDNYIERLNDLNIDFEKIDYIVVSHTEPDHAGSVEKLLDLAKNA
                     KVVASETAIKYLKEIVNKDFEYVAVTDGDTLSIGDKTLEFFSVPMLHWPDTIYTYIKE
                     DKTLVTCDSFGSHYSNDKIVNTLDENEEKDYLDALRYYYDCIMGPFKPSMVTAIEKIK
                     DLDIDTVCPGHGPVLTENPRKIIDLYYNWSVNEQIKLEKEVTICYVSAHGYTKIMAEA
                     IKAYIEKNSNYKVNLFDVIEHKQEDILAKIAVSQGVLFGTPTILGDALKPIWDILISL
                     NPVLHGGKVASVFGSYGWSGEGIENAMERISQLRMTAVKPFAVNFKPSNEEIDKLYSY
                     TGKFLDKLNSTFGSKKKTKKFKCVICNEVFEGDSAPSVCPVCGAKEDQFIEVEEDEVT
                     FRKDTDEYFVIVGNGAAGFYAADAIRKRNKTCKITMISNEDELTYYRPALSDGINEEL
                     GSDFYMEDKDWYDKNNIVVILGTNVDKLDEVNKTIIVNDGAIKFDKLVIATGSRNFIP
                     PIKGHDLENVFTLRNIKDLYSVKEALEKSKKVVVIGGGLLGLEAAWEFRLKGLEVVVV
                     EAMDSILSKQLDKEGSKILEQCVRDTGIDVRLGVAVDGIEGDGKAQKVVFKDGDSVDC
                     DMVVFSIGVRANTQMVQDTSVKIDRGIVVDKTLQTNVKDIYACGDVAQVGNISLAIWP
                     SSVEMGKIAGANASGDNLTFESEVYPVSLDAMNVKVFSIGNIQNFDKEISSKDEGQRI
                     YKKLFMKDGSLVGAILINDLSCTVKLIRLISEKGDFEDIMKADIL"
     gene            10235..10936
                     /locus_tag="ACGI5H_000255"
     CDS             10235..10936
                     /locus_tag="ACGI5H_000255"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_021418928.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="vancomycin resistance response regulator
                     transcription factor VanR-G-Cd"
                     /protein_id="HFG9695988.1"
                     /translation="MNENILIVDDEKEIADLIEVYLKNEGFTVYKFYTGKEALECIES
                     KNLDMAILDIMLPDIDGFHICQKIREKYYYPIIMLTAKIEDIDKIMGLTIGADDYITK
                     PFNPLEVVARVKTQLRRYMRYNNSYEQQSIIVNEYDIKGLIINKETHKCSLFGKEVAL
                     TPIEFSILWYLCEHQGKVVPSEELFEAVWGEKYLDNNNTVMAHIGRLREKIHEPSKNP
                     KFIKTVWGVGYTIEK"
     gene            10986..12068
                     /gene="vanS"
                     /locus_tag="ACGI5H_000256"
     CDS             10986..12068
                     /gene="vanS"
                     /locus_tag="ACGI5H_000256"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012816161.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="vancomycin resistance histidine kinase VanS"
                     /protein_id="HFG9695989.1"
                     /translation="MRTALMAFIAIIFIWILYSFILYGKFSIWIVSFFENAFRMEYKA
                     ALNLYQQIFRNSMELFMILAMVIVFFIIFRVYLNWFTKYFSEINQGIDSLIKEDVGEV
                     ALSPELLAIEKKINSIKHILEQRKFETQMAEQRKNELIVYLAHDLKTPLTSVIGYLTL
                     LRDESQISEELRKKYLSISLDKAERLEDLINEFFEITRFNLSNISLEYSTVSLTRMLE
                     QLTYEFKPTLMSKNLKYTLNVTPNMMIRCDVNKMQRVFDNLLRNAVYYSFEDTTIEIT
                     AVQEDDYIKLKFINHSNTIPEEKLERIFEQFYRLDTSRNSNSGRAGLGLAIAKEIVEL
                     HNGTITAHSENNIIIFKVIIPIVGNL"
     gene            12329..13429
                     /gene="vanG"
                     /locus_tag="ACGI5H_000257"
     CDS             12329..13429
                     /gene="vanG"
                     /locus_tag="ACGI5H_000257"
                     /EC_number="6.3.2.35"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_021418924.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanine--D-serine ligase VanG"
                     /protein_id="HFG9695990.1"
                     /translation="MNNKKIAVIFGGNSTEYDVSLQSAFAVLENLNTEKYDIIPIGIT
                     REGNWYHYIGDYNNIQNNTWFERDTDIIPVIVSQNRVKNGIIEFLIPDAVSQNHIPNS
                     AIESCENDIKYTKLDFVFPVLHGKNGEDGTVQGLFELAGIQVIGCGTLSSALCMDKDK
                     SHKLVHSEGIKVPKSILLKYSDKFNVAELSKDLTYPLFIKPVRAGSSFGISKIYKKEE
                     LQVAVDLAFEHDNEVIIEENIDGFEVGCAVLGNDDLLVGRVDEIELSKGFFDYTEKYT
                     LKSSKIHMPARIDLDCEKRIQETAKIIYRTLGCSGFARVDMFLTPSGEIIFNEVNTIP
                     GFTSHSRYPNMMKGIGLSFEEILDKIIEVYIK"
     gene            13426..14232
                     /locus_tag="ACGI5H_000258"
     CDS             13426..14232
                     /locus_tag="ACGI5H_000258"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436406.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M15 family metallopeptidase"
                     /protein_id="HFG9695991.1"
                     /translation="MMNNILLDKNKEDKMTNTILLTKDKVYDGNLILVNAFLPVKTSE
                     DIDLIPVDTRFPSILMKREATNILQNILKSICGINEIVPVSGYRTAEEQQDIYSSSLR
                     DNGKDFTKKFVALPNHSEHQTGLAIDLGLKKEVIDFICPEFPYNGICNEFRKAALHYG
                     FIERYQCKKEEITGISQEPWHFRYVGYPHSEIINKMNLALEEYIEYIKRFSYTNCLKI
                     EDKEKIIEIFYVPIHTKEEVRISIPEQCVYQISGNNKDGFIVTFWRNRKD"
     gene            14250..16388
                     /gene="vanT"
                     /locus_tag="ACGI5H_000259"
     CDS             14250..16388
                     /gene="vanT"
                     /locus_tag="ACGI5H_000259"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436408.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016747 - acyltransferase activity,
                     transferring groups other than amino-acyl groups [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="serine racemase VanT catalytic subunit"
                     /protein_id="HFG9695992.1"
                     /translation="MIRNKSYAGLDYFRIIAALLIIAIHTSPLLSYSKMADFVLTSII
                     ARIAVPFFFMLSGFFLISTYNYNCNKLKSFLKNVLFIYGIAIVIYIPLNIYTGYFSMN
                     NLVPNIIKDIVFDGTLYHLWYLPASIIGASIAYFLVKRLGLKYSLVITIVIYVIGMFG
                     DSYYGFLEKIPLLKNLYGYIFEVSDYTRNGIFFAPVFFILGGIISNKSNYMSTKNSLI
                     GFLISFLLMLCEGMFLHKLGVQRHDSMYIMLLPCMYFLFTALTFLKGSRARLLRTSSL
                     IIYIIHPMMIVVIRMFSKIFGIQTVLVDNSLIHYIVVSIASFIASIIIILILKPLKKD
                     LKGEHKVNTNRAWIEIDLNNLEHNVKMIQKAMPEDCELMAVVKANAYGHSAFEVATCA
                     NQIGVKAFAVATIDEGIDLRRYGILGEILILGYTNPIRAKELHKYNLTQSVIDLNHAI
                     SLNKQKYNIKSHIKIDTGMHRLGFDVNDVRSILKAFKLKYLDICGIFTHLCVSDSLKD
                     EDVDFTNKQIECFYKLIDFLLKKGIKIPKVHIQSSYGFFNYPNLKCNYVRIGIALYGI
                     LSSPNDTTKLQLDLRPVLSLKSQVILIRKIQKDDSFGYGRVFIASRDSVIAILSIGYA
                     DGIPRNLSCGKSYVIINGCRAAIVGRICMDQLAVDITDIPNVEVGNTAIIIGRDNLSE
                     LSASEVANNSCSISNELLSRVGRRLNVIKK"
     gene            16702..17322
                     /locus_tag="ACGI5H_000260"
     CDS             16702..17322
                     /locus_tag="ACGI5H_000260"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436409.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VTT domain-containing protein"
                     /protein_id="HFG9695993.1"
                     /translation="MQYIQELLDLTQNYWVLATIIGLLSAFIESFIPALPLVAIVTAN
                     AAIQGLFIGCLLSWIGSGLGTTSLFLLISRFNDSKLFNKLRNSKTEKAISWMDKQGFK
                     LLFIAYACPFMPGCLVTIASAFGKKDLKDFVPAMLAGKFVMFIVISYVASDIEGFITS
                     PLKIASFILLVFLSWKIGNRVNKNLENHNYDFHHKKHHNDKDDKMI"
     gene            complement(17488..18057)
                     /locus_tag="ACGI5H_000261"
     CDS             complement(17488..18057)
                     /locus_tag="ACGI5H_000261"
                     /inference="COORDINATES: protein motif:HMM:NF016214.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="metal-dependent hydrolase"
                     /protein_id="HFG9695994.1"
                     /translation="MFIVTIQEDFYMIKETHERGGYIFALLILPFINNLYLVKYDIAY
                     KIVLIIIYIYFAYLGSLFPDIDMRGSYISKKFMLIYKLFGSRFRHRGFTHSLIALLLI
                     YSFFKSLTIFTNNNIVFSCLSSGFIIGYLSHLCLDLITKEGIELFYPITINISLLPIK
                     TNSKTEKFISKLLNFIVIFLIGYQFYILL"
     gene            complement(18137..18841)
                     /locus_tag="ACGI5H_000262"
     CDS             complement(18137..18841)
                     /locus_tag="ACGI5H_000262"
                     /EC_number="1.15.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889536.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004784 - superoxide dismutase activity
                     [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="superoxide dismutase"
                     /protein_id="HFG9695995.1"
                     /translation="MKKKILIPVIMSLFIISQCITSFAFTPENNKFKVKPLPYAYDAL
                     EPYIDKETMKLHHDKHYQAYVDKLNAALEKYPELYNYSLCELLQNLDSLPKDIATTVR
                     NNAGGAYNHKFFFDIMTPEKTIPSESLKEAIDRDFGSFEKFKQEFQKSALDVFGSGWA
                     WLVATKDGKLSIMTTPNQDSPVSKNLTPIIGLDVWEHAYYLKYQNRRNEYIDNWFNVV
                     NWNGALENYKNLKSQD"
     gene            19014..20888
                     /gene="asnB"
                     /locus_tag="ACGI5H_000263"
     CDS             19014..20888
                     /gene="asnB"
                     /locus_tag="ACGI5H_000263"
                     /EC_number="6.3.5.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436426.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004066 - asparagine synthase
                     (glutamine-hydrolyzing) activity [Evidence IEA];
                     GO_process: GO:0006529 - asparagine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="asparagine synthase (glutamine-hydrolyzing)"
                     /protein_id="HFG9695996.1"
                     /translation="MDGNISIYYKGDISKKEDIKFKIKESVNNTRLSSRIEYKDEEKT
                     FDFERFNVIDAIYGNKPFEKDGKVIVFNGNIYNYHEIKEELIKKGHNFTTNDDIEVLL
                     ASYIEFGKNCVHKIKGMFNFIIYDRENESIFGARDLFGIKPLYYINKENAIIFSSEYK
                     FLLEYMKNLNINERSLQSYFSFQYVLPEDTMIQGIRLIPAGHYFRVENGILSLKRYNK
                     LEFRSSTKFFYTKNHLGNRDVNEDDIRNIVVDSIVTHMEEEKEIGTFLSGGIDSSIIT
                     TVASQINPNIKSFSAGFSVKGYSELEVAKKTADKLGIENIQINITQDEYIKSLPNVIY
                     SLDDPIADPSEVGLYFLIKEAGKHVKVALSGEGADELFGGYNIYKEYSTMKSVVNSPT
                     YIKSILGRVSELMPNIKGRNYLYRATTPLEKRYIGNAKVFENSEVKRFFFKYKEKNIY
                     EYLLSNLYRDAQKNNYDYISKMQHIDVNTWLQGDILQKISKLSTAEQVELRVPFLYKD
                     VFDVAKNLRMEQKINKNNTKVLLREAFREIVPEHVVQRKKLGFPTPIRVWLKDSLGDI
                     VKETIYNSNVDEFIDKKYAIKLLDTHLKGHRDNSRKIWTIFTFCLWHQLFIEHKNVEY
                     "
     gene            complement(20980..22416)
                     /locus_tag="ACGI5H_000264"
     CDS             complement(20980..22416)
                     /locus_tag="ACGI5H_000264"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728870.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="trypsin-like peptidase domain-containing
                     protein"
                     /protein_id="HFG9695997.1"
                     /translation="MICTIKPLKISIKKSTEPLIEFISDTTYKNKSSSYIKEVYFTRY
                     IGVDDSIDKYIEKIKNIDTYFFNNPTIPYIRLNNLKINFDKEQTDKMLKIFNIYNSSK
                     FNSWDLYNIDFPCKIENDTLNWTKKIAFKNTLDLFSTSMPNCTSSIIKNFAVKLLCWI
                     DYFLPKLFYNKVKTTISPKIVYFGNIKRQELFFLYFLSQLGCDILYINPNKDILDLYP
                     ECSKFSTLFELSRKTPNILEIPFERHITNINYSENTNKTSPTTNKPNSKNTLNNTNLT
                     SKKIVQDEEVELSYEDLAKLSASVVMIVVCNNENKPFKSGSGVVINNEGYILTNLHVV
                     NDGYSFLVRFENDDKVYTSYQIIKYHSDYDLAVIKVDRKCKPIPVKVSKKPVRGQKIV
                     AIGSPLGLFNTVSDGIISAFRDFETVQMIQFTAPISSGSSGGALLDMFGNLLGLISAG
                     YDDGQNLNLAVESSLVKIFANNFIEIVN"
     gene            22672..23070
                     /gene="tnpA"
                     /locus_tag="ACGI5H_000265"
     CDS             22672..23070
                     /gene="tnpA"
                     /locus_tag="ACGI5H_000265"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011100796.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="IS200/IS605 family transposase"
                     /protein_id="HFG9695998.1"
                     /translation="MYKSNKNIVYDCKYHIVFCPKYRKPVLVGEVEKMLKEILPYKAD
                     ELGAEIIEMETDKEHVHLLISCDPQYGIHKVVKGLKGFSSRVLRENFPHLKSSMPSMW
                     TNSYFVGTVGSVSLEVVKQYIENQQVRTKK"
     gene            23067..24230
                     /locus_tag="ACGI5H_000266"
     CDS             23067..24230
                     /locus_tag="ACGI5H_000266"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435058.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-guided endonuclease InsQ/TnpB family
                     protein"
                     /protein_id="HFG9695999.1"
                     /translation="MIKTHRVKLNLTRTQFELVREKQMESANCWNYIVNLSKEYYFEH
                     KQWIKKNDIQKLIKGKYNLHSQTIQAISDKFDANRKTISELRKKGNTKAKYPYKTKKF
                     YIIPFKASAINRNAKGNLKLSMSKGRYLELDFNVENIKTAEIVWRNGYYLYYTFDNEL
                     NGVVAKGTNTVGVDLGEIHSIASVTNKGVGLILSNREGRSIKQFRNKMYAYISKRLSK
                     CKKGSRQSKKLWRLKNKIRSKTDNQLMNLYHQTTRKFIDFCVEQKVCEIVLGDIKGVE
                     KDTKKKKRLNRVNRQKISQMEYGRIKDYIKYKAKEQGIEVKLVKENYTSQTCPKCSKK
                     HKPTGRTYSCTCGYETHRDIVGAWNILNKKHKYGLVDFRINHKQPINLKVSTV"
     gene            complement(24614..25126)
                     /locus_tag="ACGI5H_000267"
     CDS             complement(24614..25126)
                     /locus_tag="ACGI5H_000267"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895309.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nitroreductase family protein"
                     /protein_id="HFG9696000.1"
                     /translation="MLEVIKNRRSIRTYIDKNIEEDKITEILKSAMQAPSSKNAQPWE
                     FIIVDDKELLKQLSKSQHRAKHIEFAPLCIVVLGNRDKFLKPGKWIQDLGACTQNLLL
                     EVTNQGLAACWAGVFPKNKVVNKVRQTLDLPLKLVPYALISIGYSEEKNEFIDRFDEN
                     KIHRNVYKNR"
     gene            25576..26052
                     /gene="purE"
                     /locus_tag="ACGI5H_000268"
     CDS             25576..26052
                     /gene="purE"
                     /locus_tag="ACGI5H_000268"
                     /EC_number="4.1.1.21"
                     /EC_number="5.4.99.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425290.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009320 - phosphoribosylaminoimidazole
                     carboxylase complex [Evidence IEA];
                     GO_function: GO:0004638 - phosphoribosylaminoimidazole
                     carboxylase activity [Evidence IEA];
                     GO_process: GO:0006189 - 'de novo' IMP biosynthetic
                     process [Evidence IEA];
                     GO_process: GO:0009152 - purine ribonucleotide
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="5-(carboxyamino)imidazole ribonucleotide mutase"
                     /protein_id="HFG9696001.1"
                     /translation="MKVAVVMGSKSDYPKLEEGIKLLEKYGIEVVARALSAHRTPEQL
                     SIFLKEIEDDTDVIIAAAGKAAHLPGVIASQTLIPVIGLPIKSSTMDGLDSLLSIVQM
                     PKGIPVATVTIDLGLNAALLALQIMTLKYPKLKEDLKSYREEMAQKVLEDDNNLRG"
     gene            26058..26756
                     /gene="purC"
                     /locus_tag="ACGI5H_000269"
     CDS             26058..26756
                     /gene="purC"
                     /locus_tag="ACGI5H_000269"
                     /EC_number="6.3.2.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006772094.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004639 -
                     phosphoribosylaminoimidazolesuccinocarboxamide synthase
                     activity [Evidence IEA];
                     GO_process: GO:0006164 - purine nucleotide biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylaminoimidazolesuccinocarboxamide
                     synthase"
                     /protein_id="HFG9696002.1"
                     /translation="MLLYEGKAKQVYSTDNENEYVVYYKDDATAFNGEKKAEISSKGI
                     LNNKISTIIFEMLKENNINTHFIKSLSDREMLVKKVEILPLEVIVRNIAAGSICKRVG
                     LEEGVVFDEPIFEISYKNDAYGDPMLNDDYAVAMKLATREELKFLREETLKINELLKA
                     FFLKLNLKLVDFKIEFGKDSEGNIILADEVSPDTCRLWDVNTNEKLDKDRFRKDLGDL
                     VEGYTEVLSRMNNK"
     gene            26768..28135
                     /gene="purF"
                     /locus_tag="ACGI5H_000270"
     CDS             26768..28135
                     /gene="purF"
                     /locus_tag="ACGI5H_000270"
                     /EC_number="2.4.2.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425288.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004044 - amidophosphoribosyltransferase
                     activity [Evidence IEA];
                     GO_process: GO:0009113 - purine nucleobase biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="amidophosphoribosyltransferase"
                     /protein_id="HFG9696003.1"
                     /translation="MCGVLGIYSNKDVTKELYYSLYSMQHRGQESCGLALLDDGEIKY
                     KKDMGLVGDVFKENELSKLKGNIGIGHVRYSTAGGSHVSNCQPLVGSCRKRQLAIAHN
                     GNLVNANYLKDMLEEDGYMFQTNSDTEVILYILARYYKGDIVESLKVTMDYIKGAYAL
                     VIMSQEELVAVRDPHGFRPLVLGKKGDEYIFASENCAIDILGGEVIRDVEPGEIIVVK
                     DGELKSYFYSENYKPVKKSCIFEHIYFARNDATIDNVNAYEFRIKCGERLAQNETVKA
                     DMVVPVPDSGWPGAIGYANASGLKISEGLVKNRYVGRTFIKPTQEEREIAVKIKLNPL
                     STIIKGKSIILVDDSIVRGTTSKQLVKSLREAGAKEIHLRITSPPVAYSCYYGIDTPN
                     RSKLIASSNNVEEMREYIGCDSLKFLDIEGMLDATEHKSTFCKACFDGEYPVKKIDKE
                     ELLSC"
     gene            28129..29205
                     /gene="purM"
                     /locus_tag="ACGI5H_000271"
     CDS             28129..29205
                     /gene="purM"
                     /locus_tag="ACGI5H_000271"
                     /EC_number="6.3.3.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895312.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004641 -
                     phosphoribosylformylglycinamidine cyclo-ligase activity
                     [Evidence IEA];
                     GO_process: GO:0006189 - 'de novo' IMP biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylformylglycinamidine cyclo-ligase"
                     /protein_id="HFG9696004.1"
                     /translation="MLTYKESGVDIDEGNRAVDLIKGKIKGTYDGNVVGDLGNFSGLY
                     SLKDFVGMKEPVLLASTDGVGTKLKIAQMMDKHDTVGIDLVAMCVNDLICQGAKPLFF
                     LDYIALGKLVPEHIEKIVGGIADGCKMSGCALIGGETAEMPGMYGEDDYDLAGFSVGI
                     ADKEKIVSGNNVKSGDVLVGISSSGVHSNGFSFIRKIFLETYNYKMERYVEELGMTVG
                     EALLTPTKIYVKLALDVLAKHDIKAVAHITGGGLIENITRVIPKGLGLDINKKSWEKP
                     PIFKMIEGFNAVDERELHKSFNMGIGLVLIVDKENADDVVNFINNRENDNADYVDKKY
                     SELLEDKAYIIGEVVDSHEGVELC"
     gene            29199..29792
                     /gene="purN"
                     /locus_tag="ACGI5H_000272"
     CDS             29199..29792
                     /gene="purN"
                     /locus_tag="ACGI5H_000272"
                     /EC_number="2.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420972.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004644 - phosphoribosylglycinamide
                     formyltransferase activity [Evidence IEA];
                     GO_process: GO:0006189 - 'de novo' IMP biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylglycinamide formyltransferase"
                     /protein_id="HFG9696005.1"
                     /translation="MLNIGVLISGGGTNLQAVIDGTESGEIKGQVKVVISSKQGAYGL
                     ERAKNHNIKAICETDEDKIIEILKENKIDLVVLAGYLKIISPKLVNEFRNKMINIHPS
                     LIPSFCGAGFYGEKVHQGVIDYGAKVTGATVHFVDEGADTGPIIMQDVVKVNQDDDAK
                     TLAKRVLEVEHRILKESISLFCENKLKLQGRRVFINE"
     gene            29785..31317
                     /gene="purH"
                     /locus_tag="ACGI5H_000273"
     CDS             29785..31317
                     /gene="purH"
                     /locus_tag="ACGI5H_000273"
                     /EC_number="2.1.2.3"
                     /EC_number="3.5.4.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436063.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003824 - catalytic activity [Evidence
                     IEA];
                     GO_function: GO:0003937 - IMP cyclohydrolase activity
                     [Evidence IEA];
                     GO_function: GO:0004643 -
                     phosphoribosylaminoimidazolecarboxamide formyltransferase
                     activity [Evidence IEA];
                     GO_process: GO:0006164 - purine nucleotide biosynthetic
                     process [Evidence IEA];
                     GO_process: GO:0006189 - 'de novo' IMP biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional
                     phosphoribosylaminoimidazolecarboxamide
                     formyltransferase/IMP cyclohydrolase"
                     /protein_id="HFG9696006.1"
                     /translation="MSKRALISVTDKTGVVEFAKELNKLDYEIISTGNTFKTLKENGV
                     NVMQVEDVTNFPEILDGRVKTLNPYIHGGILYKRDKESHVETVNEHKIHSIDLVAVNL
                     YDFEGTLKAGKSHDEIIENIDIGGPSMIRSAAKNYKDVIVVVDIKDYDSIIEKLKTDT
                     MTLEDRKKLSYKAFSTTGRYDALISSYFAGEVGDTYPDILNLTFQKEQTLRYGENPHQ
                     NGFLYSQSNAKNPILNYEQLGGKELSFNNLNDLHGCLEVMREFKDSEEVVSVAIKHAN
                     SCGVGLGKDAFEAYTKCYEADKVSIFGGIVGITSTIDKATAEKLNEIFLEIVVAYDFE
                     PEALEILKQKKNLRILKLAKIENSLQPYEMKYLDGKLLIQDRNNILAEKSENVTKEKP
                     TDAQLKDMEFGMRVVKNMKSNAIAIVKNGQTLALGCGQTSRIWALKNALENNKDKDFT
                     GAVLASDAFFPFDDCVTLAHEYGISAVVQPGGSIKDKDSIEACDKYDMVMVFTGIRHF
                     KH"
     gene            31328..32578
                     /gene="purD"
                     /locus_tag="ACGI5H_000274"
     CDS             31328..32578
                     /gene="purD"
                     /locus_tag="ACGI5H_000274"
                     /EC_number="6.3.4.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888045.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004637 - phosphoribosylamine-glycine
                     ligase activity [Evidence IEA];
                     GO_process: GO:0009113 - purine nucleobase biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylamine--glycine ligase"
                     /protein_id="HFG9696007.1"
                     /translation="MKILVVGGGGREHAICWKLSKEKNVEKIYCAPGNAGIANVAECV
                     NIGDTNIEELLKFAKENEIGLTIVGPEVPLVMGIVDEFEKEGLRVFGPNKKCAQLEGS
                     KAFSKEFMIKHNIPTAKYKEYTNLEEAISEIDSFGYPVVIKADGLAAGKGVVIPENRE
                     DAIATLKEMMSDKKFGAAGDKIVIEEFLKGIETSILAFVDNDTIVPMASAKDHKKVNN
                     YEQGPNTGGMGTFSPSEIYTEELANKVKETVLEKTLEGFKKDGLNFKGILFVGLMITE
                     DGEKVLEYNVRFGDPETQSVLFRLETDLHEIMEAILDNKLKDIEINYSDDEAVCVMLT
                     SGGYPDSYEKGKIITGLENLDDDIVVFHSGTKMFDGNLVTNGGRVIGITAKSTTVKDA
                     AEKVYENIKKINFEGMHYRTDIGR"
     gene            32603..36409
                     /locus_tag="ACGI5H_000275"
     CDS             32603..36409
                     /locus_tag="ACGI5H_000275"
                     /EC_number="6.3.5.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860677.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004642 -
                     phosphoribosylformylglycinamidine synthase activity
                     [Evidence IEA];
                     GO_process: GO:0006189 - 'de novo' IMP biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylformylglycinamidine synthase"
                     /protein_id="HFG9696008.1"
                     /translation="MLNTENKDSMVRRVLVEKREGFDLEAKALKKDLVESLHIDNIEN
                     LRILNRYDVEGISEEVYENAAKTIFSEPNLDVVYYEEIPKLNDERVFAIEFLPGQYDQ
                     RGDWAAQCVQIVNQGIRPAINTAKVYILSGKITDEEFSKIKDYCINPVDSREASLEKP
                     ETLKMETEIPTTVEVLDGFIDLDENGLKTFVSEKGLAMTLGDLQHVQKYFKDTEKRNP
                     TITEIKVLDTYWSDHCRHTTFMTEIENVKIEDGKFNDIVKEAYQMYLNSRDNVYVNRH
                     KDICLMDIATVAVKELKKNGKLNDLDESEEINACSINVDVEVDGKMEKYLVMFKNETH
                     NHPTEIEPFGGAATCLGGAIRDPLSGRSYVYQAMRVTGSADPRTTLEDTLPGKLMQRK
                     ITTEAAHGYSSYGNQIGLTTGQVAEVYDENFVAKRMEIGAVIAAAPKENVVRERPEAG
                     DVIVLLGGKTGRDGCGGATGSSKEHSEESILTCSAEVQKGDAPNERKIQRFFRNKEVA
                     QMIKRCNDFGAGGVCVAIGEIADSLDINLDLVPKKYDGLDGTELAISESQERMAVAIK
                     KENKDKFIQLAVEENLEATHVATVTDTGYLRMFWNGKAIVDINREFLDTNGVKQTTDV
                     HVTKVDEENTFFSSNEIVKDVKCASMKDKFTKVLSDLNVCSQKGLVEMFDNTIGGNTV
                     LMPFGGKYQATPTQGMVAKIPVLGGETNTSTIMTYGYNPKVGKWSPFHGALYAVVESV
                     CKLVAIGGNYSTTRLTFQEYFEKLGNNPEKWGKPFSALLGAFYAQSKFEIPAIGGKDS
                     MSGTFKDIEVPPTLVSFAVDTVDAKKVVSPEFKKADSKVVMLCVNKAENDVVDFEELK
                     RNLDKVRELIHGNKVLSTYALGFAGVGEAISKMAFGNKIGFKFSEEAEKAFTDDKLFE
                     ASYGNIVLELANDDLSMLEGYNYVVLGSTVKETSIFIKGEELALDELYKAHCSTLEPI
                     FPTKTEEVKSKIETISYISQGEAKKSSLSIATPRVFIPAFPGTNCEYDSARAFERAGA
                     NASIRVFKNLTYKDIEDSIDTIVNEIKSSQIIMLPGGFSAGDEPDGSGKFIATVFRNP
                     RVQEAINEFLTQKDGLMLGICNGFQVLIKLGLVPYGEIRVPSESAPTLTYNNIGRHQA
                     KIARTRISSNKSPWLAQTNVGDIHNIAISHGEGKFVASEDVMRELIANGQVATQYVDF
                     NNEATYDIEFNPNGSFYAVEGITSADGRVFGKMGHSERIGEEVYKNIIGEKDQKIFES
                     GVKYFR"
     gene            36615..37487
                     /gene="rfbD"
                     /locus_tag="ACGI5H_000276"
     CDS             36615..37487
                     /gene="rfbD"
                     /locus_tag="ACGI5H_000276"
                     /EC_number="1.1.1.133"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008831 - dTDP-4-dehydrorhamnose reductase
                     activity [Evidence IEA];
                     GO_process: GO:0009243 - O antigen biosynthetic process
                     [Evidence IEA];
                     GO_process: GO:0019305 - dTDP-rhamnose biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="dTDP-4-dehydrorhamnose reductase"
                     /protein_id="HFG9696009.1"
                     /translation="MKILITGSNGQLGKELVNQLEAINQSINQPKYVILATTRSDLDI
                     SNQTNVDNFILHNKPDVVVNCAAYTKVDACEDNIEIAYKINALGVRNLAIASEKVNAK
                     LIHISTDYVFNGFSKYPYREDNKTEPNSVYGKSKLMGEKFVEQFSHKYFILRTAWLYG
                     NGNNFVKTMIKLSLENKEVNVVNDQFGTPTSTVDLAKIIIKIMETEHYGVYHATCEGE
                     CSWYDFAKKIFKLKNIDIKVNPIKSNEFKCKAPRPLYSVLDNFMLKLIGLNSFRKWEE
                     SIEEYLERYDINEK"
     gene            37596..38465
                     /gene="rfbA"
                     /locus_tag="ACGI5H_000277"
     CDS             37596..38465
                     /gene="rfbA"
                     /locus_tag="ACGI5H_000277"
                     /EC_number="2.7.7.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436059.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008879 - glucose-1-phosphate
                     thymidylyltransferase activity [Evidence IEA];
                     GO_process: GO:0019305 - dTDP-rhamnose biosynthetic
                     process [Evidence IEA];
                     GO_process: GO:0045226 - extracellular polysaccharide
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-1-phosphate thymidylyltransferase RfbA"
                     /protein_id="HFG9696010.1"
                     /translation="MKGIILAGGSGTRLYPITKCISKQTLPIYDKPMIYYPMSVLMLA
                     GIQDILIISTPRDIKAFEELFGDGSSLGLNITYAIQEKANGIAEAFIIGEEFIGNDRV
                     SLVLGDNIFYGYGFSERLENAVKRKGATIFGYHVSNPNSFGVVEFDKDFNVLSIEEKP
                     TVPKSNYAIPGLYFYDNDVVEIAKLVEPSDRGELEITSINSEYLKRGKLKVELLGRGM
                     AWLDTGTHKGLLDASNYVEVVQTRQGLYIACLEEIAYTKGYISREQLMKLAKPLIKTE
                     YGQYLLKLASEDM"
     gene            38514..39071
                     /gene="rfbC"
                     /locus_tag="ACGI5H_000278"
     CDS             38514..39071
                     /gene="rfbC"
                     /locus_tag="ACGI5H_000278"
                     /EC_number="5.1.3.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888049.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008830 - dTDP-4-dehydrorhamnose
                     3,5-epimerase activity [Evidence IEA];
                     GO_process: GO:0019305 - dTDP-rhamnose biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="dTDP-4-dehydrorhamnose 3,5-epimerase"
                     /protein_id="HFG9696011.1"
                     /translation="MGKINVIKTKIEGLYIVEPNVFYDERGYFMESYNKKDFIEQGLD
                     MCFIQDNESSSRKGVLRGMHFQVKYPQGKLVRVTEGEVFDVAVDLRKDSQTFGKWEGV
                     ILSDKNKKQFYIPEGFAHGFLVLSEKAVFSYKCTNYYYPEFENGFIWNDKQISIEWPL
                     KGIEEIFLSEKDKKQKSFKDICTRR"
     gene            39109..40092
                     /gene="rfbB"
                     /locus_tag="ACGI5H_000279"
     CDS             39109..40092
                     /gene="rfbB"
                     /locus_tag="ACGI5H_000279"
                     /EC_number="4.2.1.46"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009904815.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008460 - dTDP-glucose 4,6-dehydratase
                     activity [Evidence IEA];
                     GO_process: GO:0009225 - nucleotide-sugar metabolic
                     process [Evidence IEA];
                     GO_process: GO:0019305 - dTDP-rhamnose biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="dTDP-glucose 4,6-dehydratase"
                     /protein_id="HFG9696012.1"
                     /translation="MKKILITGGAGFIGSNFIHYMLNKYVDYFIVNLDLLTYAGNLET
                     LIEIQDNSNYKFVKGDISNREQVYKLFEEERFDIVVNFAAESHVDRSVENPDLFIKTN
                     IIGTQVLLDASIKYGVKRYHQISTDEVYGDLPIDRKDLFFTEQSSINPSSPYSASKAS
                     ADLLVSSYYRTYGLLTTISRCSNNYGPYHFPEKLIPLMILNALENKQLPVYGNGENVR
                     DWLHVYDHCTAIDLIIHKGNIGEIYNIGGHNERSNLEVVKMILNLLGKSEELISYVND
                     RPGHDLRYAIDATKIENELGWKAKYDFDLGIKETVKWYIENESWWKAVLSV"
     gene            40122..40790
                     /locus_tag="ACGI5H_000280"
     CDS             40122..40790
                     /locus_tag="ACGI5H_000280"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lytic transglycosylase domain-containing
                     protein"
                     /protein_id="HFG9696013.1"
                     /translation="MNEISSLINILALTQLSGSNTTNQCNCTYNNSSGFDMIMMTLLK
                     ALSQNNQHTSNSYNLLSNSENLFNELDNVVNNTTSRFIDVDTKDKNVKLRIENAVNQA
                     SKKYNVDSNLIKAIIKVESDFNPNTVSSAGAKGLMQLMPENCRDLGVTDPFNIEQNID
                     AGTRHIKEYIDMFGGSIEMGLMAYNGGPGRMKSRGVESISDLYKMPKETQNYIPKVMK
                     YYRG"
     gene            40799..41227
                     /locus_tag="ACGI5H_000281"
     CDS             40799..41227
                     /locus_tag="ACGI5H_000281"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860679.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YaaR family protein"
                     /protein_id="HFG9696014.1"
                     /translation="MGINIDKLNISPSINMEVKKLKESNKFSDKLNSLKQSSSLEDIK
                     RNLESVKKAGERLVLTQNYGDISIYKNAVKEYLKSVVDNMYSLDKNSSFWEHQYYKNV
                     KIVDSKLEDMTSKLISEEKENIDIVSTVDMIQGLLIDMYR"
     gene            41251..41565
                     /locus_tag="ACGI5H_000282"
     CDS             41251..41565
                     /locus_tag="ACGI5H_000282"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888052.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FliM/FliN family flagellar motor switch protein"
                     /protein_id="HFG9696015.1"
                     /translation="MNSKKEDIYELNFGQLIEEKSGVIEENQNVFNAKVKVAVSIGNT
                     TETIKNILDLKEGSIIKLSKNVDEKLDIYANDRLFAYGESIITNEKLSVRLSKIEDSD
                     VN"
     gene            41716..41991
                     /gene="flgM"
                     /locus_tag="ACGI5H_000283"
     CDS             41716..41991
                     /gene="flgM"
                     /locus_tag="ACGI5H_000283"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009901737.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0045892 - negative regulation of
                     DNA-templated transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar biosynthesis anti-sigma factor FlgM"
                     /protein_id="HFG9696016.1"
                     /translation="MDIKNVSSNIVVNNYLKNTSGIKKVEEVKKINKTDKIELSKFAK
                     EMASVSNMSDENIRNKKVDEIKNALENGTYKIKPKEIAKKMIEDMRG"
     gene            41996..42412
                     /locus_tag="ACGI5H_000284"
     CDS             41996..42412
                     /locus_tag="ACGI5H_000284"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420988.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar protein FlgN"
                     /protein_id="HFG9696017.1"
                     /translation="MITDLKVIIYEEKNIISKMMELLKEQFDYIVEKDLENLNMLNPK
                     LEDISRELASIEIKRRQLFGNDISMSEVVENSNDGYLKEIYTDLKRILALAKNQQESN
                     DSLIKKELIFTKKMINFIKPADKQTTTYNSYGNIRK"
     gene            42430..43740
                     /gene="flgK"
                     /locus_tag="ACGI5H_000285"
     CDS             42430..43740
                     /gene="flgK"
                     /locus_tag="ACGI5H_000285"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009424 - bacterial-type flagellum hook
                     [Evidence IEA];
                     GO_function: GO:0005198 - structural molecule activity
                     [Evidence IEA];
                     GO_process: GO:0044780 - bacterial-type flagellum assembly
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar hook-associated protein FlgK"
                     /protein_id="HFG9696018.1"
                     /translation="MAGLFSILNTANSGMNAHQKAIQTISHNISNLDTDGYSRQRTEF
                     ATNSPMYMPSLSNSIARGQLGTGVHVTDVTRARNSFYDYQFRAEAHKYGKTVSKYDYY
                     NTIETILNEPSDYGISAGIDDFFKGWESLSKDINSDSKKSLVVENASNLATLISESYK
                     KLDKLKEDIDSNIDTEIKQINDMLKSLEDLNKSIDIISGSGSTPNDLLDERDRILDNL
                     SFKLDFENSDVKNMLADGKLELNELKNPDGTWKTGISGTLQGLFEMHGKIDTYKSDLK
                     DVSDGLAKQINDVYNTSAGITVTDFFITSNVDGEDIIKINPAIKSNPNELKLTADEAS
                     KIAKLKDEKIDIGVAGGKVSTISDHYKAFAESIGLDSQKVNQDEANQRKIINNIDNSR
                     MSVSGVSLDEEMTELIKIQRSYQASAKVMSTAVQLLDVVINGII"
     gene            43759..44691
                     /gene="flgL"
                     /locus_tag="ACGI5H_000286"
     CDS             43759..44691
                     /gene="flgL"
                     /locus_tag="ACGI5H_000286"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860684.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009424 - bacterial-type flagellum hook
                     [Evidence IEA];
                     GO_function: GO:0005198 - structural molecule activity
                     [Evidence IEA];
                     GO_process: GO:0001539 - cilium or flagellum-dependent
                     cell motility [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar hook-associated protein FlgL"
                     /protein_id="HFG9696019.1"
                     /translation="MRVSTGMMSSSYLNSLQDNLQRLDKVNRQVNTTKEINKLSDNPY
                     KAIKILNSKSEIKTMETYVENCKDTGNWLETTDTALDQLGKLLSDIKKTLVASGDGAY
                     SDDELKTLSNETNEKMKEIANALNATHEGKYIFSGSNTGVPPVECIDNADGSVSLKFN
                     SSLNLNKLNDSLSMDIAQGISVDYNVKLSSLGFDPTKTDPFEELNNISKKLANPDADA
                     IKELTTTCLGDMEQLIENTVNVRSIYGTKANTVEAMKEKNDDSLIQLKDILSQNEEID
                     YGEKLVQLKAAELTYQASLQTGGKLFNVSILDYI"
     gene            44707..45099
                     /gene="fliW"
                     /locus_tag="ACGI5H_000287"
     CDS             44707..45099
                     /gene="fliW"
                     /locus_tag="ACGI5H_000287"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436041.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0006417 - regulation of translation
                     [Evidence IEA];
                     GO_process: GO:0044780 - bacterial-type flagellum assembly
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar assembly protein FliW"
                     /protein_id="HFG9696020.1"
                     /translation="MMKVTLKKGILGFENLKEYELLDIEDNDYLKEFNSTEEEGIGFV
                     VVSPFEIINEYEIVLNQETIEKLEVKSPKDVVLFNIITLGQTFEESTVNMKAPIVINI
                     KTNFGMQIILQDDKYSIRHPLLRGDNGC"
     gene            45093..45305
                     /gene="csrA"
                     /locus_tag="ACGI5H_000288"
     CDS             45093..45305
                     /gene="csrA"
                     /locus_tag="ACGI5H_000288"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436039.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_process: GO:0006109 - regulation of carbohydrate
                     metabolic process [Evidence IEA];
                     GO_process: GO:0006402 - mRNA catabolic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="carbon storage regulator CsrA"
                     /protein_id="HFG9696021.1"
                     /translation="MLVISRKKDEAVLIGESIEVKIVGVDGNNVKLAISAPNNISILR
                     KEIYEKVKSENIKATNKNIKILKSLK"
     gene            45327..45722
                     /gene="fliS"
                     /locus_tag="ACGI5H_000289"
     CDS             45327..45722
                     /gene="fliS"
                     /locus_tag="ACGI5H_000289"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860686.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0044780 - bacterial-type flagellum assembly
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar export chaperone FliS"
                     /protein_id="HFG9696022.1"
                     /translation="MYGENPYNSYKQNAVFMASKEQLLLMLVDGAVKYTKIARAAILD
                     KNTQKAHRELVRVQDIFTELMVTLDQNAGQWAKDMYKVYDFVRYELSRANIRKDIQVI
                     DNVLPVIEQIKDTWHEADKKSKEERSRYK"
     gene            45722..46078
                     /gene="fliS"
                     /locus_tag="ACGI5H_000290"
     CDS             45722..46078
                     /gene="fliS"
                     /locus_tag="ACGI5H_000290"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895325.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0044780 - bacterial-type flagellum assembly
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar export chaperone FliS"
                     /protein_id="HFG9696023.1"
                     /translation="MELNLAELDKLSKEELLLMLVDGTVKYTNISKEALLNNDYLKAH
                     NELVRVQNIFTELMTTLDQNAGQWAKDMYKVYEFIKSELAIADENKDIKIIDDILPIV
                     KQIRDTWHEVYNQLKI"
     gene            46099..47622
                     /gene="fliD"
                     /locus_tag="ACGI5H_000291"
     CDS             46099..47622
                     /gene="fliD"
                     /locus_tag="ACGI5H_000291"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895326.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009288 - bacterial-type flagellum
                     [Evidence IEA];
                     GO_process: GO:0007155 - cell adhesion [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar filament capping protein FliD"
                     /protein_id="HFG9696024.1"
                     /translation="MSSISPIRVTGLSGNFDMEGIIEASMIRDKEKVDKAKQEQQIVK
                     WKQEIYRNVIQESKDLYDKYLSINSPNSIVSEKAYSSTRITSSDESIIVAKGSAGAEK
                     INYQFAVSQMAEPAKFTIKLNSSEPIVRQFPPNASGASSLTIGDVNIPISEQDTTSTI
                     VSKINSLCADNDIKASYSEMTGELIISRKQTGSSSDINLRVIGNDNLAQQIANDNGIT
                     FINDAGGNKVANVYGKNLEADVTDEHGRVTHISKEQNSFNIDNIDYNVNSKGTAKLTS
                     VTDTEEAVKNMQAFVDDYNKLMDKVYGLVTTKKPKDYPPLTDAQKEDMTTEEIEKWEK
                     KAKEGILRNDDELRGFVEDIQSAFFGDGKNIIALRKLGINESENYNKKGQISFNADTF
                     SKALIDDSDKVYKTLAGYSSNYDDKGMFEKLKDIVYEYSGSSTSKLPKKAGIEKTASA
                     SENVYSKQIAEQERNISRLVEKMNDKEKRLYAKYSALESLLNQYSSQMNYFSQAQGN"
     gene            47625..47960
                     /locus_tag="ACGI5H_000292"
     CDS             47625..47960
                     /locus_tag="ACGI5H_000292"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436034.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar protein FliT"
                     /protein_id="HFG9696025.1"
                     /translation="MDKLKEKLNLYKDISLQIINLIEKEEYIKISIKLGERQEIINSV
                     SEIDRNDFIQLYNRMELIEIDSRIRDILQGQLLEVKKELHEYKLTKQVNTMYYNLNRE
                     KVNIFNKKV"
     gene            48062..48934
                     /locus_tag="ACGI5H_000293"
     CDS             48062..48934
                     /locus_tag="ACGI5H_000293"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860690.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005198 - structural molecule activity
                     [Evidence IEA];
                     GO_process: GO:0071973 - bacterial-type
                     flagellum-dependent cell motility [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="flagellin"
                     /protein_id="HFG9696026.1"
                     /translation="MRVNTNVSALIANNQMGRNVNAQSKSMEKLSSGVRIKRAADDAA
                     GLAISEKMRAQIKGLDQAGRNVQDGISVVQTAEGALEETGNILQRMRTLSVQSSNETN
                     TAEERQKIADELLQLKDEVERISSSIEFNGKKLLDGSSTEIRLQVGANFGTNVAGTSN
                     NNNEIKVALVNTSSIMSKAGITSSTIASLNADGTSGTNAAKQMVSSLDVALKELNTSR
                     AKLGAQQNRLESTQNNLNNTIENVTAAESRIRDTDVASEMVNLSKMNILVQASQSMLA
                     QANQQPQGVLQLLG"
     gene            49027..51168
                     /locus_tag="ACGI5H_000294"
     CDS             49027..51168
                     /locus_tag="ACGI5H_000294"
                     /EC_number="2.4.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888063.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HFG9696027.1"
                     /translation="MLLSIVMIVKNEEKILEKTLKSLTTLRNSIESELIIVDTGSTDD
                     TIKISKKYTEKVYFHNWNNDFSSMRNISISYAKGEWLLILDADEILIDSSTIVKFFKD
                     GLDKKFNSASIQLKNLYSYDKKLYGYCSVLRLFKNVDFRYHGKVHEQPIYKNPIFNNV
                     ADFEHYGYLFEDEEIRLNKVKRNEKLLFQELKENDNSPYTNYQLGKNFIILGKYQEAL
                     YYLEKSYELYSKLELAPGYLITSLVKTYLYLGKHKKCERLCLKYIKKDMNNIDIYYYI
                     AQAQVDLGKYENSIDSYKRYIYLLDNYEISTQANSLFSDTDTVGLRDEAIITLIKIYY
                     KLEKYEFVISEYNNIEDVEKKKNVYFSLFMSLYKLNRFEDIKNYYKEVSNSKIEKNSF
                     YRNIEEVINNIKEDEKEYVYKILCDIEGNYGILNQIRINKCVSIDKCKEILNEEKEII
                     YAYIIKIAFEEKIDLLDIFYEMEYVWIEKYLKYLLALERSFNLVLYKYIISRPNTSDM
                     EKIRVYKAISKVVLESISLSDEKYKEIFYLYIMYSYKYIRYIYSNLSDFELIKFVCND
                     LDKFTIEFKHLLDIKNKVNNANEKLEYIHSMRKLLNEYPFYNKIIKILIGELEENIKE
                     SEEFKDLKDSFIISIENMIETGKINDAKLLVDDYSKTFVDDIKILNIKGILYMFENKL
                     DKADFMLKKALSLDVENEDTIYNIEYLKSLR"
     gene            51192..53069
                     /locus_tag="ACGI5H_000295"
     CDS             51192..53069
                     /locus_tag="ACGI5H_000295"
                     /EC_number="2.4.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892587.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HFG9696028.1"
                     /translation="MNIPIVVNEKSKDIIKDWQYTCTNEDIKFTSIIILTYNQIEYTK
                     LCIESIRKFTPKNKYEIIIIDNNSSDGTVEWLKGQSDIKSVYNNKNLGFPKGCNQGIE
                     LATGENILLLNNDVIVTPNWLYNLNKALWSQDNIGAVGPITNACSYYQQIDVDYKSIE
                     DMFIFAHKINKSNINLWKYRLKLVGFCMLIKKTVLDNVGVLDELFTPGNFEDDDLSFR
                     MIESGYKLLLCQDTFIHHFGSVSFKENRNKYTDIMYINRRKFETKWGFNPEYSGMIRT
                     DLISKIDDSLEANINVLEIGCGIGATLLEIKNIYKNASIYGIEISESAGKLAKYSADV
                     LIANIEKVKLDYKKDFFDYIILGDVLEHLIDPWKIVNELKQYLKKDGYLVSSIPNIMH
                     VSVLRNLVLGNFTYEDSGILDKTHLRFFTLNEITKMFNDSNYIINSITATSMPLSEID
                     NSFIDTICKESCKEMRQQYESYQYIVKASKILDTKRYSSISMINLKYALMRIDNELDV
                     DSNLSYIFDNYNITEPCFVDDIEYLIDTFVINKATLLNRLGVEAFNRGLGDFSINMFM
                     TVLEMDRDDIDSIYNITSVLCELEEFDTAYNLIKNSSEKVQSESDIQEILCFIEGKKY
                     E"
     gene            53062..55176
                     /locus_tag="ACGI5H_000296"
     CDS             53062..55176
                     /locus_tag="ACGI5H_000296"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892588.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HFG9696029.1"
                     /translation="MNNDKICFITCVNDERLYEECLVYINSLDIPKNFSIETVALRGA
                     DSIASAYNKAMRETDSKYKVYLHQDTFIINKNFIHDILEIFKKNTDVGMIGVAGVKDM
                     PVNGIWWDSDKKAGKVYDSHTGKMDIYEFSNFEECFNEVMAIDGLIMITQYDVFWRED
                     KFDGWHFYDLSQSMEFRQNKYKVIVPKQNKPWCMHDSGVVNINNGYDEYRIKFVKEYI
                     NLDLYRENFYEFDKKKASTILKSNKHVMDCMKEELTEQLRLKNYKDVLGIVSKIAHFS
                     VFNHTGLYSCEECERALLECANNLPEIENTKLFTKKDLKRRKVLHVLSEGYSTGGHTR
                     LVKNWIEIDKDSVHSVVTTWQSDTLPDWLLKAINDSGGEVISLDLISDDYLKRAVALR
                     KIAYDWADIVILYVHMWDTIPVVAFGVDGKIPILHVNHYDSTFWLGTSIADIVIDFSE
                     ASQLITLDKRGIDKSEILPMPLKEKEVFSKSEVRKRYNLEDDVTIILTIASERKYNSV
                     NDINYFKIAKTLIENTDNTIIIVVGVDTENLYWKTLSNVTDNRVICFGTTANIDDFYK
                     ISDIYMESFMVGSHTSKLDAILYDLIPVKFKNEVSPIFTNMWNFIDKFDYKNIKEVID
                     MIKRYNTSEFDRDRIKEKQSEIKHFVIDKHCIEIKNYIDKIYNEANHHKVKYDLYKND
                     EIEDYQLFVALYGYMVKNKNMS"
     gene            55185..56180
                     /locus_tag="ACGI5H_000297"
     CDS             55185..56180
                     /locus_tag="ACGI5H_000297"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436022.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016755 - aminoacyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0044038 - cell wall macromolecule
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="peptidoglycan bridge formation glycyltransferase
                     FemA/FemB family protein"
                     /protein_id="HFG9696030.1"
                     /translation="MNNIHINKFEKSCERNWDYFVENKSINGTFLQTRNFLNYHEEGK
                     FTDHSLIICKGEEILAVVPACETYEDGERIFFSHLGSTFGGIIIRSGFNDIRHVNAIT
                     NKLEIYLREQNFDKVYLKNTSRIFCKEDTSLLEYFLFKNNYMFYDELSMFLELSKYKE
                     DILANFKYSKRRDFKYSLKNNLTFKRLYSDEDIVCFFNLLSNCLDSKGAKVIHSVEEL
                     LEFKNNRLKDIVEFYAVYIDDIMICGSMVFNFQERVYHTQYLASNSTYNKYYPMIFLY
                     YNLIKDALERNFKYLSFGISTLNRGKYLDEGLATFKEGFGSSAICNRTYYKNINK"
     gene            56272..57504
                     /locus_tag="ACGI5H_000298"
     CDS             56272..57504
                     /locus_tag="ACGI5H_000298"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888065.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-grasp domain-containing protein"
                     /protein_id="HFG9696031.1"
                     /translation="MKRLMILGSIKYFENIVISAKKEGIYTIVCDNRIDTPAKKICDE
                     AIDVDVFDFDKIKSIAIDKKIDGILTGFTDSLMKPYVYIANELNLPCVISCNQLESVT
                     NKAIMKKYFKNNAIPTTDYCIIESLKDLEKIQGLNFPLVIKPVDGYGSRGVYFVSNIE
                     ELIEKFEYSKEASQDGQVIIEEFYESEEIQGLAWVHNGESHVFYIGDRELVNIHTGRA
                     GKPDRLLYPSKYCFQYEEEIKSIYQNITQAFDIKNGPLYVQMLVGAYGIKVSEVMPRL
                     PGGCDYMAISQITDLDIGSLFANFSVNNEVNFDEIKKYNMHLSKCVYALPIYIRPGTI
                     KKINNIDKIENLDYVTQFLLLVKEGDTIELYEDERQDCGRVYGIANNIFDANIKKKCI
                     HEMIEILDENNENMIENF"
     gene            57524..58468
                     /locus_tag="ACGI5H_000299"
     CDS             57524..58468
                     /locus_tag="ACGI5H_000299"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895329.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ornithine cyclodeaminase"
                     /protein_id="HFG9696032.1"
                     /translation="MKLITHEQIMSLNISQKQGYEWIKESFLTKKDCQLPPKISMVEE
                     GHVFYNVMPSLNHNHMIGGIKMVTRLPGRNPSLNSEIFLYNMEDAKLKAILDGNYITA
                     FRTAAVAALAIDTFAKKDFNTIAIMGLGVTASAIMNMLSYTLKDKNINIKLLKYKDQA
                     ELFVKKYEKNEQFSFEICDTHEELIVDSDVVISTVTYTDEYLSEFKWFKKGALLLPVH
                     VMGFGNVDYLFDKVYLDDYNHLKHLENIDRYKYSCEFYDVLSKQAKGRENDDERIISY
                     NIGLSIHDILFANKIYELCETLSCEEIELKEPKEKYWI"
     gene            58562..58969
                     /locus_tag="ACGI5H_000300"
     CDS             58562..58969
                     /locus_tag="ACGI5H_000300"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895330.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FdtA/QdtA family cupin domain-containing
                     protein"
                     /protein_id="HFG9696033.1"
                     /translation="MDKYNLIRFVSIGNEYIGNLVALESNKVIPFDIKRVYYIYDVPN
                     NVKRGFHAHKNLEQVLVCLNGSVKIKCYDGVKETIFNLHKNDVGLYIGTGVWHEMFDF
                     DEKTVLISIASEHYNEEDYIRDYKEFLKYLNNV"
     gene            59047..60147
                     /locus_tag="ACGI5H_000301"
     CDS             59047..60147
                     /locus_tag="ACGI5H_000301"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012815981.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DegT/DnrJ/EryC1/StrS family aminotransferase"
                     /protein_id="HFG9696034.1"
                     /translation="MNLLLVKFNNLLKQFQTHKEEYEQKIKDVMESGYYILGNEVKHF
                     EEEFANYVGSKYCVGLASGLDALIIAFRALGISKGDEVIVQSNTYIASVMGISINGAT
                     PVFVEPNEYYNIDSSKIEEKINSKTKAILVVHLYGQASNMKDIQELCDKYNLYLIEDC
                     AQSHGAKYDGKMTGTFGDIGCFSFYPSKNLGAFGDAGAIVTSNEEIADKVKILRNYGS
                     EKRYYNKFVGYNSRLDEIQAGLLRVKLKYLNEIEIEKSKIVDRYLNEINNPKVILPKI
                     ENNCTHVWHLFVLQVEKRDTFMEYLKKSGIESIIHYPIPPHLSEAYAYLGYKKGSFNI
                     AENYSDKVVSIPLFIGMEDEEVSYIIKIINEY"
     regulatory      60456..60546
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF01051"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="cyclic di-GMP riboswitch class I; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /bound_moiety="cyclic di-GMP"
                     /db_xref="RFAM:RF01051"
     gene            60956..61273
                     /gene="flgB"
                     /locus_tag="ACGI5H_000302"
     CDS             60956..61273
                     /gene="flgB"
                     /locus_tag="ACGI5H_000302"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860696.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar basal body rod protein FlgB"
                     /protein_id="HFG9696035.1"
                     /translation="MNTYDIIKMGLDATNLRSQTIANNIANINTEGYKRHYITFEETL
                     NDAMPKIEEKTDNSKGLRVDGNNVDIEEEKVNQAMATLQYNALISFANGKIAMTKSII
                     SGR"
     gene            61281..61685
                     /gene="flgC"
                     /locus_tag="ACGI5H_000303"
     CDS             61281..61685
                     /gene="flgC"
                     /locus_tag="ACGI5H_000303"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425244.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0030694 - bacterial-type flagellum basal
                     body, rod [Evidence IEA];
                     GO_process: GO:0071973 - bacterial-type
                     flagellum-dependent cell motility [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar basal body rod protein FlgC"
                     /protein_id="HFG9696036.1"
                     /translation="MSVFSGMRISASGLTAESLKMDIISSNVANINATRGPNGEAYRR
                     KVVSFEENYDNKLGMLGVKVTSVEDDKSPLKEVYDPSHPDAKPNGYVEYPNVNILVEM
                     TDLITASRAYDSNVDTLNAQKSMISKALEIGK"
     gene            61695..62012
                     /gene="fliE"
                     /locus_tag="ACGI5H_000304"
     CDS             61695..62012
                     /gene="fliE"
                     /locus_tag="ACGI5H_000304"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425242.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009431 - bacterial-type flagellum basal
                     body, MS ring [Evidence IEA];
                     GO_function: GO:0003774 - cytoskeletal motor activity
                     [Evidence IEA];
                     GO_process: GO:0071973 - bacterial-type
                     flagellum-dependent cell motility [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar hook-basal body complex protein FliE"
                     /protein_id="HFG9696037.1"
                     /translation="MPITQINNLMQGAKLDNLIGEAKPLTLNNKEEKKNFEDVIIDTI
                     DKVNFQQVTADDMKEKFIKGEDVSMHEVMLIGQEAQLSMQYLIEVRNKIHDAYQEMNK
                     VQI"
     gene            62037..63587
                     /gene="fliF"
                     /locus_tag="ACGI5H_000305"
     CDS             62037..63587
                     /gene="fliF"
                     /locus_tag="ACGI5H_000305"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425240.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009431 - bacterial-type flagellum basal
                     body, MS ring [Evidence IEA];
                     GO_function: GO:0005198 - structural molecule activity
                     [Evidence IEA];
                     GO_process: GO:0001539 - cilium or flagellum-dependent
                     cell motility [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar basal-body MS-ring/collar protein
                     FliF"
                     /protein_id="HFG9696038.1"
                     /translation="MITSFKNKIKEQVAKSRTKISSLKKGTKIALGIGVIAICLALVF
                     TAISASKNKYAVLFSELDAQDAADISAELESKKIDTKVKGSTIYVPRTEVDKLRLELA
                     PSLTGGSKGFALMDDSSSIGLTDEEFQIKKQRMIQGEIEKTIKSFPQVEDTRVHITFG
                     ESSVFEKEAVPGSAAVYLMLKPGTTLEKNQIKSVMALISGSVTNIPEKNVQVIDNKMN
                     LLSEGILEDENVDENNQPINSGISVDKNKASEQALNKQLEKSILEMLEPIFGKGKVKA
                     TVNADLSFDTAEKTEIKIDPDKVAIKETRSKNSSKSAANNVQGVDANMNNQGNNNGTN
                     TEDSLDESFEYETGKIETHTIVAPGELNRLTASVAIDGKIAKGVQADVEDIVNNAIGM
                     DGARGDTLSVVSMVFDPEGKKEAKQELEEIKKEGFKKNIIKAVIGVVAVIAVGAIGYL
                     IYKKRSEREDMDYEDEDYISKSDSVDRKDNPLLGDDPELTLEEAVKMYAEEKPDQVTE
                     IIKTWLNE"
     gene            63600..64670
                     /gene="fliG"
                     /locus_tag="ACGI5H_000306"
     CDS             63600..64670
                     /gene="fliG"
                     /locus_tag="ACGI5H_000306"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009901747.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009288 - bacterial-type flagellum
                     [Evidence IEA];
                     GO_function: GO:0003774 - cytoskeletal motor activity
                     [Evidence IEA];
                     GO_process: GO:0006935 - chemotaxis [Evidence IEA];
                     GO_process: GO:0071973 - bacterial-type
                     flagellum-dependent cell motility [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar motor switch protein FliG"
                     /protein_id="HFG9696039.1"
                     /translation="MSTEITNVNAFDLSDINESDKNEKVEGEGLKKAAVLLMTLGPNV
                     SSDIIKSLPDKQVQKIGLEIANISSIASKERREILKEFVEINRAKDYVIEGGLEYARE
                     LLSNALGNVKANKLLEGISINTSTKPFKHIIKLDVKKILEILRNESAQTIAVLLAHME
                     PENGAEVLSYLDFDLQNEVAMRISSMGSISPEVIKVIESSLEDKLHSISGDDFNDYGG
                     VSTLVQILINSDRKTEKNILGTIEEQNPDLAAQIKSHIFVFEDIVKLDDISIQKVLKE
                     VTMKDLVYALKGVDDEISDAIYRNQSSRAADALKEEMEMVGVIKVTQVEASQQKIANI
                     VRKLEREGAITIVRNFGGDFVE"
     gene            64654..65394
                     /locus_tag="ACGI5H_000307"
     CDS             64654..65394
                     /locus_tag="ACGI5H_000307"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425235.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FliH/SctL family protein"
                     /protein_id="HFG9696040.1"
                     /translation="MTLLNNKIIKSKKALYKGVLDLTIIDKVRVGESNVNKENDCRFR
                     DEVIKEAIESAEIRKNEILEEAKMNAQNIEKQAYEKGYSQGQKNGYEDGYKESYDEYT
                     QKAKDEADFIKNQADLILLQANEKMTEYIKEKNKEIVRLAINMASSVLKKHFEDEESM
                     SDLLKQIIQDYEGSSSFIVRCNSFYKDNIEKEFELFKEETSLKSSVFVIADDSIDKGN
                     AIIQKENGRIIVGIDCAMEKLKEELLGE"
     gene            65398..66717
                     /gene="fliI"
                     /locus_tag="ACGI5H_000308"
     CDS             65398..66717
                     /gene="fliI"
                     /locus_tag="ACGI5H_000308"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009901749.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_process: GO:0044780 - bacterial-type flagellum assembly
                     [Evidence IEA];
                     GO_process: GO:0071973 - bacterial-type
                     flagellum-dependent cell motility [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar protein export ATPase FliI"
                     /protein_id="HFG9696041.1"
                     /translation="MYKTDISIDFDKINKKIENLELTISEGRVKKIIGLTVEVEGIKA
                     FVGELCVIYNQVNKPVNCEVVGFKDKEVILMALGELTLIAPGCKVISKGIPLSVMCSD
                     NLLGKVLDGLGNPIDNSDAVLGDRYNLNNEPPDPMKRKKIRNIMETGVRAIDAFTTCG
                     EGQRIGIFAGSGVGKSTTLGMIARNAKADVNVIALIGERGREVLDFIDKDLGEEGMKK
                     SVVVCATSDKAPLVRLKGALTATAIAEYFRDQGKKVILMMDSVTRFAMAQREVGVAIG
                     EPPAQKGYTPSVFAMLPKLMERTGTSDKGSITAFYTVLVDGDDFNEPIADTTRGILDG
                     HIVLSRDLANKNHYPSIDVLNSLSRLMNEIASKEDIKIASFARDMLAEYREAEDLINI
                     GAYASGTNKKIDEAIYYHEHIINFLKQGINEKSSFNETISSLRRIFE"
     gene            66749..67195
                     /gene="fliJ"
                     /locus_tag="ACGI5H_000309"
     CDS             66749..67195
                     /gene="fliJ"
                     /locus_tag="ACGI5H_000309"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012815984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009288 - bacterial-type flagellum
                     [Evidence IEA];
                     GO_function: GO:0003774 - cytoskeletal motor activity
                     [Evidence IEA];
                     GO_process: GO:0071973 - bacterial-type
                     flagellum-dependent cell motility [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar export protein FliJ"
                     /protein_id="HFG9696042.1"
                     /translation="MELDKNFKFRLQKVLDLKIKDEEEIKMEFAKIQQKKIDIETNLE
                     NLESNYSKYSISKNNDNVQNQKITINYLLALNNSIMDLSEELDKSTNELEKARKQLIS
                     KQIERKSLEKLKEKKYGQYYKEEQLKEQSTNDEFASMSYLRNRQVL"
     gene            67223..68428
                     /locus_tag="ACGI5H_000310"
     CDS             67223..68428
                     /locus_tag="ACGI5H_000310"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435997.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar hook-length control protein FliK"
                     /protein_id="HFG9696043.1"
                     /translation="MKIQADSYNIIKDIGNRKNSSKNKNIKNNKFEDNLYKTTDHKNV
                     KDRRETSKQNVSSDRPGNSDNECHLDEDKSNHLEDENTYEKDCSKNNEALQQLLNLLK
                     ENYKKDKDINTILNNIKKLSISDELKQELKLNKNILNKIANQNLELNGANTNNPNDIE
                     NLDIMKLRELLENNASEDIQVISKTTENDTKSIDLYSFDSNRMDTLNSNKQKDDSSDI
                     LEKLAGLNGNKSGNFGQVINKSVDMNKIKNDNVNLKQIESNVMDDSIKAIKHMKTNDI
                     QELTIKLRPKELGDMNIQLLKDGESMRAVVTVFNKDVFDSINKNIADLKQHLELTNVN
                     IKDVSVQMHSDNTNTSDTFDKAFEQQNRQNNQENMSNQNTNDKRNNVVIEDEIKENII
                     DDDRVDLLA"
     gene            68446..69054
                     /locus_tag="ACGI5H_000311"
     CDS             68446..69054
                     /locus_tag="ACGI5H_000311"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888079.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar hook capping FlgD N-terminal
                     domain-containing protein"
                     /protein_id="HFG9696044.1"
                     /translation="MYGIATALAGTQVNYRSNNLSQLERNINDIANKQVRSKGNQTVT
                     DNGTPIIGQGDDADKDLFMKILVAQMGNQDPMNPQDPTEYVSQLAQFATLEKMSAMND
                     KLDILLALSNSTLINSALSMATSLIGKEVEVSGEEDEDENIVGVVKSTYIKDGEVHLE
                     LEVDGSDKTVDVKYEKLLKIGEVEANSGEENDSSEQESPEEV"
     gene            69081..70064
                     /locus_tag="ACGI5H_000312"
     CDS             69081..70064
                     /locus_tag="ACGI5H_000312"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435994.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar hook-basal body complex protein"
                     /protein_id="HFG9696045.1"
                     /translation="MIKAMYSGVSGMKANQTKLDVIGNNVANAGTTSFKKSSARITDS
                     FYQTVLYASAPTAALGGTNLGQVGVGSKISSINKDMTQGNVQPTNRPSDLMIDGDGYL
                     PVVRQGTVMYTRDGSFNLDTGFKAADGALKNIKGGRLVNGDGYMLQGMIYDGEYKADT
                     GEFVKKGDAKGKEPIVIPLQSISPKDGTVQNVLEYNISKDGTVEFLLSDGQRTQFVYD
                     IPDGAKVGDTPAGIDKLKGTIQKVQTYAFQNPAGLDAEGGNLFKPSANSGDPQIAGAT
                     GTIIQGAIEASNVDIAEEFTEMIIASRSFQANSKIISTSDEILQEIINLKR"
     gene            70077..70280
                     /locus_tag="ACGI5H_000313"
     CDS             70077..70280
                     /locus_tag="ACGI5H_000313"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar FlbD family protein"
                     /protein_id="HFG9696046.1"
                     /translation="MIRVTDLNGRKYILNSDLIVRIDSVPESRILLTTGEKNLVKESV
                     DEIVDKVIKYKRKINVGYIRSEK"
     gene            70280..71098
                     /locus_tag="ACGI5H_000314"
     CDS             70280..71098
                     /locus_tag="ACGI5H_000314"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009901756.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MotA/TolQ/ExbB proton channel family protein"
                     /protein_id="HFG9696047.1"
                     /translation="MKKTDSLTFIGLILSTVLVLFGAVKGSSSGLKSFFDFASILITV
                     FGSFGALMITFTIDDIKLIKDALQYSFKTMNISKLDLLNQFKTLSKKARREGLLSIES
                     DVMKIQDPFMKKGLELCIDGLEINEIRSILELEIDSVEETNNRYSKLFKTWGTFAPAF
                     GMLGTLIGLIQMLSDLTSPDLIASGMGKALITTFYGSLLANIALNPIAYNIDEKTEKE
                     IYVKEMMLEGIISIQSGESSIVVEERLATYLSNNEKLEIMKSNKNTERAMSNGA"
     gene            71088..71783
                     /locus_tag="ACGI5H_000315"
     CDS             71088..71783
                     /locus_tag="ACGI5H_000315"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425218.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="OmpA family protein"
                     /protein_id="HFG9696048.1"
                     /translation="MARKKNKKKDEINPDAWLATYADTITLILTFFVLLYATSVVDME
                     KFKNIADALKGQFSGTSMFSTGSSTSEKSPIESVLVDKNDKSNLEQDLKDKVNNSNLQ
                     NSVTVKDDSRGILLELDDSILFDSGISELKEDSKATLNKVYDMIKMMKNKIVIEGHTD
                     NVPVKSSTHESNWDLSSSRAVSVVRYFVEEKGMDPKLFSATGCGEYQPLVSNETAKGR
                     AENRRVNILITID"
     gene            71795..72238
                     /gene="fliL"
                     /locus_tag="ACGI5H_000316"
     CDS             71795..72238
                     /gene="fliL"
                     /locus_tag="ACGI5H_000316"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435981.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009425 - bacterial-type flagellum basal
                     body [Evidence IEA];
                     GO_process: GO:0006935 - chemotaxis [Evidence IEA];
                     GO_process: GO:0071973 - bacterial-type
                     flagellum-dependent cell motility [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar basal body-associated protein FliL"
                     /protein_id="HFG9696049.1"
                     /translation="MFKNKKIIIIILILIIFSAGAGFFILGEGGNKQIDKIAGLFIPT
                     GKGKDEVKTENLDLEEMVLKLADEGVRYLKVSITVSYDSSYKDIEKNTPLIRDNIINC
                     FMAKRADDFTADNLKNIKEEIKNTLNIQLGENVIQNIYFTNIVVQ"
     gene            72253..72627
                     /locus_tag="ACGI5H_000317"
     CDS             72253..72627
                     /locus_tag="ACGI5H_000317"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009901759.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar biosynthesis protein FliZ"
                     /protein_id="HFG9696050.1"
                     /translation="MILYLLKILICIPIILILIVLSLKISQGTLLKKYNDKYIKILDI
                     VNISKNNSIIILKIGEEGCIMASSSSSMSKIKDLTKEEILRIENDIKERNFKIQDFKM
                     ERIKKKYDFSRYIGKFTKKEDK"
     gene            72628..73293
                     /gene="fliP"
                     /locus_tag="ACGI5H_000318"
     CDS             72628..73293
                     /gene="fliP"
                     /locus_tag="ACGI5H_000318"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425215.1"
                     /note="The bacterial flagellar biogenesis protein FliP
                     forms a type III secretion system (T3SS)-type pore
                     required for flagellar assembly; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_process: GO:0009306 - protein secretion [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar type III secretion system pore protein
                     FliP"
                     /protein_id="HFG9696051.1"
                     /translation="MELLSKLPLADVPYTSSMQLFLFLTALMFLPFVMFMMTSFVRIV
                     ISLSFLKSALGAQQAIPSQILVGLAIVLTIFIMRPVLNEINEKALQPYMKEEVTMEEA
                     MKEAEGPIKEFLLKQTRQTDLDLFVEQAGLKEKKLTRENIPLSVVVPAFAISELKTAF
                     QIGFLIYIPFLIIDLVVASVLMSMGMFMLPPVMISLPFKLLLFVMVDGWNLIVKTLIL
                     GFG"
     gene            73306..73575
                     /gene="fliQ"
                     /locus_tag="ACGI5H_000319"
     CDS             73306..73575
                     /gene="fliQ"
                     /locus_tag="ACGI5H_000319"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425214.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_process: GO:0044780 - bacterial-type flagellum assembly
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar biosynthesis protein FliQ"
                     /protein_id="HFG9696052.1"
                     /translation="MSEFMIMSVLKNGMFTGAMIAAPVLIVSLVVGLLISVFQATTQI
                     QEQTLTFVPKLIAILLVVAIGGSWMLHTLISFTSEIFNMMSLITK"
     gene            73587..75401
                     /locus_tag="ACGI5H_000320"
     CDS             73587..75401
                     /locus_tag="ACGI5H_000320"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860706.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fused FliR family export protein/FlhB family
                     type III secretion system protein"
                     /protein_id="HFG9696053.1"
                     /translation="MIFVFIRIVAFFGTLRILFPAGTPALFKSLFAIIISILISSTMQ
                     IEYATNIDNIVLFTLYGINETITGIMLGYITNLCFYSIRMAGSMMDQQMGLSMINMFD
                     PNSMTQTTLINNLMNWTALMIFFSMDGHHVLIRGIRYSFELIPIGKSFIDNNIDYIIN
                     IFVQCFLTGFKIAIPIVLCLLMADFILGLISRSVPQLNVMIIGMPLKILVGIALFIIS
                     IPLIVNQISHLLSQIPKMYEGTFALAPMFFMGSTDKTEEATPKKKGEQRKKGNIAKSK
                     ELPIAMTLLAFTLLVPTLFSYVVNTLKSSLNYFLSLDFYMNINYSSIEKLVIAGLMDF
                     FKIFLPIAIPFLVLGIVANLFQVGILFTGETLKPNLSKLNPISGFKNMFSMRSLSTLI
                     KDTAIISILAYIGYTFFQDNYLDILKLGNIYLPTLMYTVKDLVYSILSKICVAMIVIA
                     VADYVYQRYSHKKQLRMTKQEVKDEYKNSEGDPEIKAKIKQKQRQISSQRTMQAVPSA
                     TVIVTNPTHLSIAVRYEKGKDQAPVVVAKGADYLAFKIREIAKGNDIPIIENKPIARL
                     LYKQVEIDQEIPEDMYQAFAEILVAVYKIKNRYKVPKR"
     gene            75410..77485
                     /gene="flhA"
                     /locus_tag="ACGI5H_000321"
     CDS             75410..77485
                     /gene="flhA"
                     /locus_tag="ACGI5H_000321"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895344.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_process: GO:0044780 - bacterial-type flagellum assembly
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar biosynthesis protein FlhA"
                     /protein_id="HFG9696054.1"
                     /translation="MNKFNLKENMDVIVAFGVVGIVLMMIVPLPTFILDILLAINISL
                     SVLILLMTLFTTNVLDLSIFPTVLLVTTLFRLGLNLSSTRLILTQGYAGEVIEAFGSF
                     VVGGNYVVGIIIFLIILIVQFVVITNGSGRVSEVTARFTLDAMPGKQMSIDADLNAGV
                     IDDKTARKRRKELQQEADFYGSMDGANKFVKGDAIAGLIVTAINIIGGIVIGAVMLNM
                     TLMGAAQTYVRLTIGDGLVSQIPALLISTSAGIIVTRASTDENFGGLVGKQLTAIPKA
                     VMMTGCVLIVLGMMPGLPKPAFFSLGIGAIAAGYFLGREKKDTLEDLEFEKPDMVNPD
                     KNEVEDVTNLINVESIEVEIGYGLISLADESAGGDLLQRIASIRRQCAIDMGIVVQPI
                     RIRDNLQLNPNQYNIKIKGNVVGGYEIMPNMVLCMDPMNQGFSIFGIKTIEPTFGIEA
                     LWIESDKVEDAELKGYTVVDSSTILITHLLDIIKSNAHELLGRQEVKTIIDAARENYS
                     AVVDELIPDLMTLGEIQKVLKNLLREKVNIKDRVTILETLADQSRNTKDIELLTEYVR
                     IALARSICNNLVDEDKAIVVATLSPETEELVSNNLQRSVNGTYPAVDPENTNKIFESI
                     QEVMNNVYFNHNIPVIVVSPKIRAPFRKLVEIVYPNLTVLSLNEIPNDIKIKAEGVVS
                     IYDDEKVYS"
     gene            77460..78476
                     /gene="flhF"
                     /locus_tag="ACGI5H_000322"
     CDS             77460..78476
                     /gene="flhF"
                     /locus_tag="ACGI5H_000322"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003924 - GTPase activity [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_process: GO:0044781 - bacterial-type flagellum
                     organization [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar biosynthesis protein FlhF"
                     /protein_id="HFG9696055.1"
                     /translation="MMTKKYTANTIQDAMNLAKMELGDNITLIDKKEVRKSGIRGIFS
                     KKDIELTIGWEKKDNLEQKDLKREIEQLKSIINNMGFDNKNDNDIDKICKNLLNLDLN
                     QEIVEFIKADLQEMKFNGIDTSKNLVESLKKKIKIENQAINGKIALVGPPGVGKTTTI
                     AKLAAKLVFEENKKVGVITIDTYRIGAVEQLKIYTDIMNIPFKGVISPDEMELALDEM
                     KDCDVVLIDTTGRGYKNSMQILEIKNLIDKAETDNIHLVLNCTTRESDTKAIIDSYRN
                     VNFKSLIITKLDETITYGSIFNIMNYAQKPISYITTGQNVPDDIIKPNEDKIIRLLLG
                     VESI"
     gene            78473..79351
                     /locus_tag="ACGI5H_000323"
     CDS             78473..79351
                     /locus_tag="ACGI5H_000323"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435971.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MinD/ParA family protein"
                     /protein_id="HFG9696056.1"
                     /translation="MIDQAQILRKMAMEKRGSDEIIVENENMPKIITIASGKGGVGKS
                     NLATNLSICLTKLDKKVLILDADIGMSNIDIIMGVNVKGTIIDVINGEKNIEDIISQT
                     KYGVNIISGGSALNHIEDFTEAQRNKFIHSIEQIHNVDFIIIDTGAGMSKSLLSFIYC
                     STEFFLITTPEPTSLTDAYSLLKAISNFGIKKSANIIINRVIDLEEAKSTYKRIKMVV
                     DKFLNLNLELYGYIIDDKKVGVCVKKQIPFILEYPTSIASKCIIAIAKRMVSQSREDI
                     VDNKSFLRKMFSIFKS"
     gene            79365..80066
                     /locus_tag="ACGI5H_000324"
     CDS             79365..80066
                     /locus_tag="ACGI5H_000324"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009901765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003899 - DNA-directed 5'-3' RNA
                     polymerase activity [Evidence IEA];
                     GO_function: GO:0016987 - sigma factor activity [Evidence
                     IEA];
                     GO_process: GO:0006352 - DNA-templated transcription
                     initiation [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-70 family RNA polymerase sigma factor"
                     /protein_id="HFG9696057.1"
                     /translation="MNREELIKENMPLVKSIARKFFIPGKGFEYQDLVNSGVIGLIDA
                     INKFDTEKGAKFSSYSYIKIKSAILDEIRNQSPISKHNLTKVNKYNRVVEKLQSKLLR
                     EPTSYEIAKELKVSEKELHDIESNIDMLNIVSLNYVIFEDTNETVQDVISDREEEAPE
                     NIIEEEEKLEILSKAISNLNEREKLILSLYYYEDLNLKEIGKVLGVSESRVSQLHRKS
                     IRNLRNKIKELKYSI"
     gene            80082..80504
                     /locus_tag="ACGI5H_000325"
     CDS             80082..80504
                     /locus_tag="ACGI5H_000325"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729253.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar protein"
                     /protein_id="HFG9696058.1"
                     /translation="MIQIILIVVSILIIVTIVINLQKESKNKDNRYFDKIFEQEYEAN
                     DRLIIAEKRRFFLDKVLAEKRINSHIKVYENYNLIKANEERKENIFIESKKEVRQENE
                     LSLKVKHLISSGYDDVEICKMLDIGKGELLLIRSCYKI"
     gene            80489..80674
                     /locus_tag="ACGI5H_000326"
     CDS             80489..80674
                     /locus_tag="ACGI5H_000326"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425206.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar protein"
                     /protein_id="HFG9696059.1"
                     /translation="MLQNIRILLCDKKVFLGIGIGILISTLCIMLFSNNDMSKAEIEK
                     KARALGMKYTSEMKVLE"
     gene            80715..81488
                     /locus_tag="ACGI5H_000327"
     CDS             80715..81488
                     /locus_tag="ACGI5H_000327"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425203.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0071973 - bacterial-type
                     flagellum-dependent cell motility [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar basal-body rod protein FlgG"
                     /protein_id="HFG9696060.1"
                     /translation="MIRGLYTAVSAMITNQQKQNVVVNNLANMDTNGYKSKQLLTKSF
                     DELKLEGYNNYANGTKQKQIIGDISPGISMDETITNFNQGPIKTTDNKMDVAIQGKGF
                     FLVSDAAGNQFYTRNGNFRTDNQGDLITSEGYYVLGTNTATGAVGHINVGNQKFEVAK
                     DNTISLDGNAMYKFNIVDFNNYNNLKKEGDNLYSGGGAMKVNNALTIQSAIESSNVDM
                     VSEINNMMTISREYEANQKIIQAMDSKLAKIASEIGSVR"
     gene            81509..82270
                     /locus_tag="ACGI5H_000328"
     CDS             81509..82270
                     /locus_tag="ACGI5H_000328"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895351.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0071973 - bacterial-type
                     flagellum-dependent cell motility [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar basal-body rod protein FlgG"
                     /protein_id="HFG9696061.1"
                     /translation="MYTMFYTSKTALSANQSKLDIISNNIANSDSTGYKKINMEYSDL
                     VDEVLNRPSYPTNGKDISTGTGAKATAPMRNYEQGALAPTDSKSNLAIDGEGFFRVIR
                     KDGTYAYTRNGGFNVDALGKIVDDNGNILDVQFDAGYNYNNTNIDSTNLTVSRNGELF
                     VDNKKIGKINLYQPIGTQNFISEGDSLFVATDAAQIKQVEKVDIVQGYRERSNVSLQE
                     EFVDLIATQRAFQMNSKGIKTADEMWQIANNLRAK"
     gene            82293..83174
                     /locus_tag="ACGI5H_000329"
     CDS             82293..83174
                     /locus_tag="ACGI5H_000329"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435965.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FliM/FliN family flagellar motor switch protein"
                     /protein_id="HFG9696062.1"
                     /translation="MNDMKEYDFGKPQSYSRENLTCLNFLLAEFCKKYKNYIIYELKC
                     NSSMVVDSIDQVNYQTFLDRVTSSCVVVQNAMEPVMKNFSFRIDRSVADMWIDITSGG
                     TGVVKDNDRELTELDKKVLLHLMDDLVRNMHLFEGFENIQVLDTHTHINLPQLCSPTA
                     PVCVVDLKVLNDNECIGSVSLCFPYNGLEALLESISVIEFFDNDVGDDSEEFTQKIYN
                     SVSNIELSVIAEIGKVSINVEDLLKLEVGDVIVTNKKINDYIDIFVENSKSYTATPGF
                     ISSKKGVKINDAVGKEV"
     gene            83177..83551
                     /locus_tag="ACGI5H_000330"
     CDS             83177..83551
                     /locus_tag="ACGI5H_000330"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888109.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FliM/FliN family flagellar motor switch protein"
                     /protein_id="HFG9696063.1"
                     /translation="MDNSNLISDEEAKMLLNDKVESEVDGDDELALDVSEVNRNNIQR
                     ILDLKLELSVVIGRTKMTLRDILNLHKGSLIELDTLADQDVEILIDNKVLAYGKVVVV
                     DLNFGVKITSIVSEEDMVKSLV"
     gene            83583..84986
                     /locus_tag="ACGI5H_000331"
     CDS             83583..84986
                     /locus_tag="ACGI5H_000331"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009901769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005515 - protein binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tetratricopeptide repeat protein"
                     /protein_id="HFG9696064.1"
                     /translation="MVLILNLNDIKKDILKLNKKDSCSLYNESINNINNNCISTGLKF
                     LKQARDLNPDDVDILNLTGLVNLLKCNFDDAVESFYKSSLCEKTALCEKYINMLTSEE
                     FLIFFEKYNQLIRLINKGMYKEAIQGFKLITDQYCDLIEPYELLALLYDKEEEYIKFD
                     ECLEVLKIIDKENYLLNQENNTLDMYNSANIQTKSNIKVDDYKNEFLHKSSSNHKIND
                     YNDVTKEKSSSKNQKSSDSNKKKSIKKNKYLYIAIILGILLVGQSIYNSYKMNNLTDK
                     ISKNNETKNEESIDSNLTKKENNIEENEDMSKASNINKSNKNINKEDDVKSKKNTVEN
                     EDDKDSDLFTEDELMSKANTLKSEKKTKSSIQLYKKVADIGENKGNTSEATYQVAILS
                     EKLKDYKTAEEYYKMYVENYSEKDAYFDESYYNLGMMYYNNGDLKNSKLTLKKLVNKV
                     PNSMYNNSKVKEILKEE"
     gene            85102..87039
                     /gene="htpG"
                     /locus_tag="ACGI5H_000332"
     CDS             85102..87039
                     /gene="htpG"
                     /locus_tag="ACGI5H_000332"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435963.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0051082 - unfolded protein binding
                     [Evidence IEA];
                     GO_process: GO:0006457 - protein folding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="molecular chaperone HtpG"
                     /protein_id="HFG9696065.1"
                     /translation="MEFEKGSISIHTENIFPIIKKWLYSDKDIFIRELISNGCDAVSK
                     HKRLVSLGEISENKSSDYKITVSVNKGEGTLKFIDNGIGMTEEEIKKYINQVAFSGAE
                     DFFNKYKDKMEESNDIIGHFGLGFYSAFMVSKKVQIDTLSYTEGATPVRWISEGGTEY
                     EISESDARNDRGTTITLFIDDDSKEFLDEFTVRGIINKYCSFLPVEIYLEDVERLERE
                     AKEAEEKAKKQKEDGKEEIVDAKVIEPLNDTNPLWLKSPKDCTDEEYKEFYRKVFNVF
                     DEPLFWIHLNVDYPFNLKGILYFPKLKNEFELTEGKVKLYNNQVFVADNIKEVIPEFL
                     LLLKGVIDCPDLPLNVSRSFLQNDRDVSKISKHIIKKVADKLKSLCKNEREEYNKFWD
                     DIQIFIKYGCLKDESFYEKVKECILFKTIDDEYITLQDYLEKCKDKHENKVFYVSDKE
                     QQSQYIKLFKEYDLSAVVLNSSIDTHFISFMEYKENGVKFNRIDADLSDVLKDKNENK
                     DSEENKEEIAKIEGLFKEAVGERVKNYSVEGLKNEDTPAMVLVSEQSIRMAEMQSRFA
                     GMDLGMNFEEEKTLVINENSPIIKKLVSLKDDEEKKDKITLICNQIADLALLSNKELK
                     PDELDSFVQRSNKLMSLLIEL"
     gene            87427..88557
                     /locus_tag="ACGI5H_000333"
     CDS             87427..88557
                     /locus_tag="ACGI5H_000333"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435962.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-containing alcohol dehydrogenase"
                     /protein_id="HFG9696066.1"
                     /translation="MNFNYNLPVNILFGSGRINDVGKEVSKYGKKVLIVTGKNSTKKT
                     GLLDKTIDLLKDSKIEYEVFDRVEQNPLITTIYSGVEIIKSTGCDCVLGLGGGSIMDA
                     AKSIAFSYKNPGDLNDYIFGIRQGEEALPIILVPTTSGTGSEGNCFAVLTNSETKDKK
                     SIKKNSMYAKASIIDPELMVTMPKHIIASVGFDALAHNMEAYLSNGRNPLADVQAIYG
                     IELISENLIKVYNDVNDLEAWEKITLASTIGGMTIGTAGTALPHGMEHPVSGLRDVMH
                     GKGLAALTPTIIESSWDSDIERFGNISKVLGGTCAEDCSDAIRNFLKKIDLDIKLSDL
                     GIEKSDIDWLTDNCMKISVANIKRHPKYFNKEQIKEMYHKSL"
BASE COUNT        35836 a         9149 c        15886 g        27754 t
ORIGIN      
        1 aaacttttga gatgtactta tttgctaata aaatagaggt gttttaatgg gaggaaattt
       61 ttatgaggaa tttacaaaaa aaattgatgt tttttttatt tatttgtata attttacaaa
      121 ttacatacac aacaccagtc tattctttat gcaaactcta taaaaacaac tccataaata
      181 actttgagtc tattgtgtct aataatcagc ttattagcaa acatgcaata caaataatac
      241 ttattatggc tataatatgt gtaatactta tattctatat aatatatgat aaattaaatt
      301 ttaaaattaa attgcaaagg atagcatata cagataatct tacaggagca aatactatag
      361 ataaatttgt aattgatgct aacaaaatac tatgtaaaaa tactcaagta aagtatgctt
      421 tattatatat agatattgat aaatttaaat atataaatga tttatttgga tatgaagttg
      481 ggaatgaaat tttgcgtaat ttaacaaaga ttattaagag caatatattt gaagaggaaa
      541 tgtttgcaag aatatctgcg gataatttta ttataattat gaaatatata gaagaagaag
      601 atataacaaa gaggttaaaa actatatttg aagaattaga cttgtttaat aataatcaag
      661 aagaaaaata taagttagtt ttaagttgtg gaatctattt tatacttcca gaagatagag
      721 atatcaactc aatcatagat agggctaata tacctcataa aatggcaaag ggaggacata
      781 aaagttcata tgcattttat gataataaga ttcatgacca agagataaaa gaaaaagaga
      841 tggaaaatac aatgttttca agtctagaaa ataaagaatt tattatatac ttacaaccta
      901 agatagaact taatacagga gagatacaag gttcagaagc acttgttagg tggaaacgtc
      961 ctgataaagg gctaatacct ccaaatgaat ttatcccatt ttttgaaaga aacggttttg
     1021 ttataaattt agatttatat gtgcttgaag aagtatgtat ataccttaga aaatggattg
     1081 atgcaggaat aaatccagtt actgtttcag ttaatgtttc aaggatacat ttatattgca
     1141 ataattttat agaaacatac aaaaatataa ttgataaata caatatacct gcaaagtata
     1201 tagaacttga attaacggag agtatcatat ttgataattt tgatatttta attgatataa
     1261 tgaataattt aaaaaaaata ggatttttaa tatctatgga tgattttggt tcagggtact
     1321 catcattaaa tatgttaaaa gaaattccta tggatatctt aaaacttgac caaaaattta
     1381 ttatggaaac ttataatagt aaaagaagca aaataattgt tactaaagta atagaaatgg
     1441 caaaagagtt gggtatgaaa gtcatatcag aaggagttga gacagaagaa cagtttaaac
     1501 ttttaaaaga agtaaagtgt gatatggcac aaggatattt gtttggaaag ccaatgccaa
     1561 ttgaagaatt tgaacattta attgtatcta acttggtaag agggtaatta atctgtaata
     1621 taaagaattt aataaattgt gttaaaaatg gactctaatg tagtgttcat tttttttgta
     1681 aaatttttta tacttttact aaaaagtaat tgacatatac tttgtattat tatattattg
     1741 tattaacaac ttaatacaat aatataataa ggaggcatga acatggaatg ggaacttgat
     1801 aataacaaac ctatatatat acaattagta gaacatttaa agttaaaaat aatttcaggg
     1861 gaaattaaaa taggatctaa attagaaaca gtgagagcac tagcagaaga tgcggaagtt
     1921 aatccaaata caatgcaaaa ggctctaaca gaacttgaaa gacaaggttt agtttatagt
     1981 cagagaacta aaggaagatt tgtaacagat gataaggaaa aaataaaagc tatgaaagag
     2041 gaaatagcta atgtggagat aaatacatta aaagtaacct tagaaaagct tggatatgat
     2101 agagatgaaa tgctaaaact tattacagaa aatctgaaag gagaattata aaatggataa
     2161 aaatataagc aatgtttctc aagatggaat agttgaattt aaaggtgtaa acaagagtta
     2221 tggaactaag aatgttttaa aaaatattga tttaaatata ccaaagggaa aaatagtcgg
     2281 gctgttagga cctaatggaa gtggcaaaag tacaatgatt aagctaatga atggattatt
     2341 acagcctgat aatggtgaaa ttatgataaa tggaatgaaa ccatccatag atactaaaaa
     2401 aatagtttca tatttaccag aaagaactta tttaaatgat tggatgaagg tatcagattt
     2461 acttaagttt ttctatgatt tttatagtga ttttgatgtt agaagagcaa atgagatgat
     2521 taaaagctta gatattgatg taaatgaaaa gctaaagaca atgtctaaag gaactaaaga
     2581 aaaagttcaa cttattttag taatgtcaag aaatgcgagc atatatatat tggatgaacc
     2641 tataggtggt gttgacccag ctgcaaggtc atatatactt aagactatat taaaaaatta
     2701 ttctgaagat agtactttac tgattgctac ccacttaata agtgaaatag aaaacatatg
     2761 tgatgagata atattcatat caaaaggaga aatagtgtta caaggagacg ttgaagcaat
     2821 aagagaagaa aaaggaaaat ctatagatgc attatttagg gaggaattta aatgttaggt
     2881 aaattattaa aatatgagtt aaaagcaagt ggaagaatat ttataccgtt atatatagcc
     2941 atattgatag tagctgtatt taatggaata tttatgaata caaatatact tcaggtacag
     3001 ggaataggaa tactagtatt aacaagtctt tttatggcat taggagtttt aactattgta
     3061 gttacaattc aaaggtttag aaaaaatctt ttgggggatg aaggttattt aatgtttact
     3121 cttcctgtta gcactagttc acttatatta tctaaatgta taacagcact tatatacgct
     3181 gtacttagtt ttatagttgc agtattcact tttggagttc ttatgctttt tggtacttct
     3241 ggaattttac tacctgaaat tttagatttg tttaacacta gttttaaatg gatttctgaa
     3301 aactttttag atattttatt attagtagta gtaatgttta tttcatattc atcatttatt
     3361 ttgttattat atacatcaat ctcaatggga caattgccaa aattcaataa acatagaaac
     3421 atagtggcat ttgcttcttt tatagctata aatatagtaa tatcaattgt tggagatgca
     3481 gttggaagca tcttaccaaa tgaagataca aatatggtat atcatcttta tcagagtcct
     3541 agttttatgc ttgcaatact tggtagtctt gtagttgcaa tagcgttatt tttcgctaca
     3601 aaatttatat tagataaaaa attaaattta gaataaatgt ttttatatgg agctatcttt
     3661 tgagtaatgt taaaagatgg ctcttattat ttatgtagtt aattcatgta tataatatga
     3721 atagtgtttt atttctagtt aaatatatac atatgttgta taatgatatt gcgtgtaaaa
     3781 atttgtaaga ataactatac actttatata agttatatca agaaaattta aaaatatatg
     3841 gatttgaggg agaagatatg aaaagttata caaaggctaa gtggagtgtt tggggtataa
     3901 ttacattttc atttgtttta gtattatttt taaggatgtc aactgctgtt gtttcagaca
     3961 atttagcaaa tgagttaggt tttaattcta tacaaatttc aaatatagca tccttttgcc
     4021 tatatgcata tgcatttatg caaatacctg caggaatttt gattgataaa tatggagcaa
     4081 gaaaaattag cagtcttgga ataataatgg caagtttagg gtcaatttta tttggtttga
     4141 ttcaaagtat agaattagca tatatttctc gtgtaattgt aggggcagga acatcagtaa
     4201 tattactttg tattttaaaa attcaaggga gatggtttaa taagtcagaa tttgcttctg
     4261 caacagctaa attttcattt gtaggaaatt taggtggagt tcttgctact tttccacttg
     4321 tgtttttgtc tgaacttgtt ggttggagaa attcattttt attaatcggt ataattggtg
     4381 ttgtaattgg atgttttatg tatattattg ttagagatac accaaaagag tatggattca
     4441 atgtagatac tgaaccctat gaaaagtcag agaaggttaa tattgttgat ggtattaagt
     4501 ctgttataaa gaacaaatca acatggtata attcaatgat aatgttctct tttgttggtc
     4561 ttacaagtgc atttataagc ttgtggggag taagatacat aatggacgtt tatggtgtga
     4621 gtaagagttt ttctgcgttt atagtatcat tttttacata tggatttata tttggttcaa
     4681 taattatgga ttttgtattt gctaaaataa ggtctagcaa atttaatata ataaaatttg
     4741 gagcaatgat agatttgttt atatggattg taattgtagt tgtataccag gtaaaaccac
     4801 caattatagt tttaccaata tcattcttta ttatgggatg tatagttatg tcacatctac
     4861 aggtttttaa tgatgccaag tataaaaata aagaaattta ttctggactg gcaactagtg
     4921 ttattaatac ttttgaattt ataggaagtg gaattattaa tttgattata gctatctctt
     4981 tacaagtaaa ttcatataat atagttgatg gatataaaaa aggttttgta gtatttatag
     5041 tactaagtat tataactata gtatcatctc atataggggt aaaaaatgat gattttaagg
     5101 ctatatagtg ttttattaat agtttaattt agtattatat tttgcatata tataacaaat
     5161 agtttgcatt ttcctaatat gtataattgg aatataaatc ttgtttacta tgtacaaatg
     5221 gtattgtatt atattaaata gaaaataaga actttaaact ataatattgg ttctaaaata
     5281 taaggtaagg agttttttat ggatacgacg aaaatagatg atataagcaa gttagattta
     5341 aataatttag atattaataa gatggatatg ggaggtataa tggaaagtct gctagaatgg
     5401 gctactacaa gcggagtaaa acttataata ggcatactta tactttctat tggatttaaa
     5461 ataataaaaa aatttgtaaa ccatgttatg ttattactta gtaaaagaga tattgattta
     5521 actttaagaa agtttttaaa gtctcttctt ttgagtgtac ttaaagttgc cgttataatc
     5581 attgttctgg aatattgggg aatgagtttg tccagttttg ctgctgtgat agcatcagca
     5641 ggggtagcaa taggtttggc tttacaaggt agtctatcaa attttgctgg aggatttatt
     5701 atactattga ttagaccttt taaagtagga gattacgtag aagcagcagg tcatggagga
     5761 acggttgaac aaataggtct tttttataca caattggtta ctccagataa taaacagata
     5821 cttataccta atggttctgt atcaaatgat agtctaataa actattcagc aaagaatact
     5881 agacgagttg atttgacttt tagtgtaggg tatgaagatg atatactaca tgttagaaga
     5941 gtacttaaag atattgttaa taatcataaa ttaataataa atgaaccaga accatttata
     6001 ggagtagtag aacatggaga taatgctatt aaatttgcaa ctagagtttg gtgcaagaca
     6061 gaagattatt ggacaattta tcttgattta ctagaagagg ttaaagttag gtttgacgaa
     6121 gaaggaatta cgattccata tcctaaaatg gatttaacgg taaaagaatt aaacaaaatt
     6181 taatttttta atatagtgtt taaatttaag aatatcatat agatatactt ataaggtttg
     6241 taaaaaatta ataagtactg ttattttgta agtaaaaata taaaaaaatg ggagtgtctc
     6301 aaaatgaact ttttagttca tgaggcactc tttttgtacg aaataaaata tatttttatt
     6361 atttcaacaa tgaaaaagag gcttgtttcc attttgagac agtataattt ttatgtaact
     6421 ttaattttag taaatataaa gttttaaaat tgataaaata ggaggaattt ttaatataaa
     6481 agggtaaata aagggtttag agggcataat atagaataaa ttaatatatt taaggagggt
     6541 ttttatgtgt aaaaaaacgt atttattagt ggtaagtatg cttatagcgg gtttattaac
     6601 tgcatgtagt gggagtccaa ctaaggattc aggacaagca caagataata caaaaaagga
     6661 ggcaaatgca tcaaataacg ctttaaaaga tgaaaaaaat aatgaaaatt taatggaaca
     6721 agattttaaa gtgccataca cagatgcaat aaacatattt aaagataaat ataaggatgc
     6781 tgatatagta gatttaagtc ttgagagaga tttaaataaa tttgtttata ctgtggaagg
     6841 tgtagatgat aataatgaat ataagatgaa aattgatgct aatacaaaag atgtattaga
     6901 agataaaaca gaaaagttgg attcagaaga tttaaatgga gttgctagaa aagaaaaatt
     6961 agatttaaat gacataatga cacctcaaca agctatggaa attgcattaa aagaacaaaa
     7021 tggaatagtt aaagaatgga gtttagacaa agatttagat gttacttttt ataaaataag
     7081 aatagataaa gataaaaatg aatatgacat aaaagtagat tctaaaaagg gaactgtatt
     7141 gaaggtagaa aaagaagatt agaagattta aactatcttt aaaataattt cttttttgaa
     7201 taaattttgt ttaaaatata acaagcaggg tataaagaga ctaaataact attttaggag
     7261 gagtacggta tgtcattgaa atcactaaaa ataaaagaaa atttatattg ggtaggttcg
     7321 cttgaccctg atttaagagt atttgacata attatgtata caccttatgg aactacttat
     7381 aattcatatg tattaaaagg aacagaaaaa acagttttat ttgagacagt taaagataag
     7441 cattttgaca attatattga aagattaaat gatttaaata tagattttga aaaaatagac
     7501 tatattgttg taagtcatac tgaaccagac catgcaggaa gcgttgaaaa gcttttggat
     7561 ttagctaaaa atgcaaaagt agtagcttca gaaacagcaa ttaaatatct taaggaaatc
     7621 gtaaacaaag actttgaata tgttgcagtt acagatggag atacattatc aattggggac
     7681 aaaactttag aatttttctc tgtacctatg cttcattggc cagataccat atacacatat
     7741 ataaaagagg ataaaactct tgtaacatgt gattcatttg gtagtcacta tagtaatgat
     7801 aagatagtaa atacacttga tgaaaatgaa gaaaaggatt acttggatgc tttaagatac
     7861 tattatgatt gtataatggg tccatttaaa ccatctatgg taactgctat agaaaagata
     7921 aaagatttag atatagatac tgtatgtcca ggtcatggtc cagtattaac tgaaaatcct
     7981 agaaaaatta tagaccttta ttacaactgg agtgtaaatg aacaaataaa gttagaaaaa
     8041 gaagttacaa tttgttatgt ttctgcacat ggatatacaa agattatggc agaagctata
     8101 aaagcatata ttgaaaaaaa tagcaactat aaagtaaatt tatttgatgt aatagagcat
     8161 aagcaagaag atattttggc aaaaatagca gtatcacaag gtgtattatt tggaacacca
     8221 acaatattag gagatgcgtt aaagcctata tgggatatat taatatcgtt aaacccagtt
     8281 cttcatggtg gaaaagttgc ttcagtattt ggttcatatg gatggagtgg agaaggtata
     8341 gaaaatgcta tggagagaat aagtcagctt agaatgacag cagtaaaacc ttttgctgtt
     8401 aactttaaac catcaaatga agagattgat aaattatatt cttatacagg taaattccta
     8461 gataagttaa attctacttt tggaagtaaa aagaaaacta agaaatttaa atgtgtaatt
     8521 tgtaatgaag tttttgaagg tgatagtgct cctagtgtat gccctgtatg tggagctaag
     8581 gaagaccaat ttatagaagt tgaagaagat gaagttactt ttagaaaaga tactgatgaa
     8641 tatttcgtaa tagtaggaaa tggagcagct ggtttttatg cagcagatgc tataagaaaa
     8701 agaaataaaa cttgtaagat aactatgatt tctaatgaag atgagttgac ttactataga
     8761 cctgcacttt ctgatggtat aaatgaagaa cttggttcag atttctacat ggaagataaa
     8821 gattggtatg ataaaaataa tatagtagta atattaggaa cgaatgtaga taaattagat
     8881 gaagtgaata aaactattat agtgaatgat ggagctatta aatttgataa gcttgtaata
     8941 gctacaggaa gtagaaactt tataccacca attaagggcc atgatttaga aaatgtgttt
     9001 actcttagaa atataaaaga tttatatagt gtaaaagaag cactagaaaa atctaagaaa
     9061 gttgtagtga ttggtggcgg tttattggga cttgaagctg catgggaatt tagactaaaa
     9121 ggattagaag tagtagtagt tgaagccatg gatagcatac tatcaaaaca acttgataaa
     9181 gaaggtagta aaatattaga acaatgtgta agagatacag gaatagatgt aagattgggt
     9241 gtagcagttg atggtattga aggtgatgga aaagctcaaa aagttgtatt taaagatgga
     9301 gatagtgtcg actgtgatat ggtagtattt tcaattggtg taagagcaaa cactcaaatg
     9361 gttcaggata catctgtaaa aattgataga ggtattgttg tagataagac attacagaca
     9421 aatgttaaag atatatatgc ttgtggagat gttgcacaag tgggaaatat tagtttagca
     9481 atatggccat cttcagtaga aatgggaaaa atagcagggg caaatgcaag tggagataat
     9541 ttgacatttg aaagtgaagt atatccagtt tcattagatg caatgaatgt aaaagtattt
     9601 agtattggta atatacaaaa ttttgataaa gaaatttcat caaaagatga aggtcaaaga
     9661 atatataaaa aattatttat gaaagatggt tcattagttg gagctatact tataaatgat
     9721 ttaagctgta ctgttaaatt gataagatta atatctgaaa aaggtgattt tgaggatatt
     9781 atgaaggctg atatactata atttaaatac attaaaataa aaaggagttg tctcaaaatt
     9841 gatttttttc taatcaaatt ttaaattcaa ctcctttttt gaatttttat ataaaataac
     9901 atggaaattt tagtaatgtc tgtggttaca tacataggtt taattgtttt ttatatggat
     9961 tgtctctggt ataataaatt gaattgtgtt tgactgatag atatttttat tgaaagttaa
    10021 tacctgttat gcgataataa ggacgtgtta ggggagtttt tataataaca attaatctca
    10081 gtttttgtgt tccaatagta gcatcaacac attctgatgt agtagttctt ttcttataaa
    10141 aattagttac aaatatgctt gtaattattt gatatgtaaa tttaccaata ttataaatga
    10201 tgacctcgat aataaggaga gtgaaaaata atctatgaac gaaaatattt tgattgtgga
    10261 tgatgaaaaa gaaatagcag atttaattga agtatattta aaaaatgaag gttttacagt
    10321 atacaagttt tatacaggta aggaagctct agaatgtatt gaatctaaaa atttggatat
    10381 ggctatttta gatattatgc ttcctgatat tgatggattt catatttgcc agaaaattcg
    10441 agaaaaatac tattatccta tcattatgtt aacagctaaa attgaagata tagacaagat
    10501 aatgggttta accataggtg ctgatgatta tataacaaag ccatttaacc ctttggaagt
    10561 tgttgcaaga gtaaagacac aattaagaag atatatgcga tataataatt cttatgaaca
    10621 acagtcgata attgttaatg agtatgatat taaaggattg attatcaata aagaaacaca
    10681 taaatgtagt ttatttggga aagaagtagc attaacaccg attgaatttt ctattctttg
    10741 gtatttatgt gaacatcaag gaaaagtggt tccttctgaa gaattgtttg aagctgtatg
    10801 gggagaaaaa tatcttgata ataataacac agttatggct catatagggc gattacgtga
    10861 aaaaattcat gaaccttcta aaaacccgaa atttataaaa actgtatggg gagtaggtta
    10921 tacaattgaa aagtaaaaat attaaagtca atcctgactt tactcaagtg agaaataaaa
    10981 tttttatgag aacagcttta atggcattta tagccattat tttcatatgg attttatatt
    11041 cttttatatt gtatggtaag ttttctatct ggatagtatc attctttgaa aatgcttttc
    11101 gtatggaata taaagctgca ttgaatttat atcagcagat tttccgtaat agcatggagc
    11161 tcttcatgat actagctatg gtgattgtgt tttttataat attccgggtt tatttaaatt
    11221 ggtttacaaa atattttagt gaaataaatc aaggtattga ctctcttatc aaagaagatg
    11281 ttggagaagt ggctttatct ccagagttat tggcaataga aaagaaaata aactcaatta
    11341 aacatatact tgaacaacgt aaatttgaga cacaaatggc agaacaacgt aagaatgaac
    11401 ttattgttta tcttgcacat gatttaaaaa caccacttac atcagttata gggtatctga
    11461 cactacttcg agatgaaagt cagatttctg aagaactgcg aaaaaaatat ttatctattt
    11521 cgttggataa ggcagagcgt cttgaagatt taattaatga attctttgaa attacaaggt
    11581 ttaatttatc aaatatatca cttgaataca gtacagtaag cttaactcgt atgcttgaac
    11641 aactaacata tgagtttaaa cctactttga tgagtaagaa tttaaaatat acactgaatg
    11701 ttacaccaaa tatgatgata aggtgtgatg ttaataaaat gcaacgtgta tttgataact
    11761 tattacgaaa tgctgtttat tatagttttg aagatactac tattgaaata acagctgtac
    11821 aggaggatga ttatataaag cttaaattta taaatcatag caatacgatt ccagaggaaa
    11881 aacttgagcg tatttttgaa caattttaca ggttggatac atctcgtaat tcaaacagtg
    11941 gtagagctgg gttgggactt gctatagcta aagaaatagt ggagcttcat aacgggacaa
    12001 taacagctca tagcgagaac aatataatta tctttaaggt tattattccg attgtaggaa
    12061 atttgtaaga atttaagtat aaaaaaatag gaaattcttt aggataaata aataaagagc
    12121 actcttgtta ttgatataat tactgtatca aaacaagagt gcttttattt tgatacagta
    12181 attatatcaa tagaaaaatg tgaaaatata ttatgtggaa cagatgcaat tgtaagtgaa
    12241 ggttgattgg atttgaaata gaaaaagtat tttaacatgt ttctgtagat tgtataaaaa
    12301 taaataaatc aacaaaggag aatcaaagat gaataataaa aaaattgcag ttatatttgg
    12361 tggaaactca acagaatatg atgtatcatt acaatcagct tttgcagtac ttgagaattt
    12421 gaatacggaa aaatatgata ttataccaat tggaattaca agggagggta attggtatca
    12481 ttatattgga gattataata atatccagaa taacacttgg tttgaaaggg atactgatat
    12541 aattccagtt attgtttcgc agaaccgtgt caaaaatggt attattgaat ttttaattcc
    12601 tgatgctgtt tctcagaatc atattccaaa tagtgctatt gaatcatgtg aaaatgatat
    12661 taaatacact aaacttgatt ttgtgtttcc tgtactgcat ggaaaaaatg gagaagatgg
    12721 aacagtgcag gggttatttg aattggcagg tatacaggtt ataggatgtg gtactctttc
    12781 ttcagcatta tgtatggaca aagacaaatc acataaactt gttcattcag aaggtattaa
    12841 agtaccaaaa tcaatattac taaaatactc agataaattt aatgtggctg aactgtcaaa
    12901 agacttaact tatccattat ttataaaacc tgtgcgtgca ggttcatcat ttggtattag
    12961 taaaatttat aaaaaagaag agttacaagt agcagtagac ttggcttttg aacatgataa
    13021 tgaagtaata attgaggaaa atattgatgg ttttgaggta gggtgtgcag ttttaggaaa
    13081 cgatgactta cttgttggaa gagtagatga aatagaattg tcaaaaggat tttttgatta
    13141 tacagaaaaa tatacattga aaagttcaaa aattcatatg ccagctagaa ttgatttgga
    13201 ttgtgagaaa agaatacaag agacagcaaa aattatttat agaactcttg gatgttctgg
    13261 atttgctaga gtagatatgt ttttaactcc atctggtgaa attattttta atgaagtcaa
    13321 tacaattcct ggctttactt ctcatagtcg ttatccaaat atgatgaaag gtattggatt
    13381 gtcttttgaa gaaatattgg acaagataat tgaggtgtac ataaaatgat gaataatatt
    13441 ttattagata aaaataaaga agataaaatg acaaatacta tcttattgac taaagataaa
    13501 gtttatgatg ggaatctaat tctagtaaat gcttttttac cagttaaaac atctgaagat
    13561 atagatttaa ttcctgtaga tacaaggttt ccaagtattc ttatgaaacg tgaagctaca
    13621 aacattttac aaaatatttt aaaaagtata tgtggaataa atgaaatagt acctgtaagt
    13681 ggatatcgta ctgcagagga acaacaagat atatattcaa gttctctgcg tgacaatgga
    13741 aaagacttta ctaaaaagtt tgtagcactt ccaaatcaca gtgaacatca gacagggctt
    13801 gctattgatt tagggttaaa gaaagaagtt atagatttta tctgccctga atttccttat
    13861 aatggtattt gtaatgagtt tcgtaaggca gcactacatt atggttttat agagcgttat
    13921 cagtgtaaaa aagaagaaat aacaggaata tctcaagaac catggcattt tcgttatgtg
    13981 ggatatccgc attctgagat tatcaataaa atgaatctcg ctcttgaaga atatatagaa
    14041 tatattaaga gattttcgta tacaaattgt ttaaaaatag aagataaaga aaaaattata
    14101 gaaatctttt atgtgcctat tcatactaaa gaagaagtga gaatctctat acctgaacaa
    14161 tgtgtatatc aaatatcggg taacaataag gatggtttta ttgtgacatt ttggagaaat
    14221 agaaaggact aagaaatgga ggaacaagaa tgattaggaa taaatcttat gcagggcttg
    14281 attattttag gattatagct gcattactta taattgcaat tcatacatct ccattattat
    14341 catatagtaa aatggctgac tttgtgttaa ctagtataat tgctcgtatt gctgtgccat
    14401 tcttttttat gctatcaggc ttttttctaa tttcaacata taattataat tgtaataaac
    14461 tgaaatcttt tctaaaaaat gtattattta tttacgggat agctattgta atttatattc
    14521 ccttaaatat ttacactgga tatttttcca tgaataattt agtgcccaat attattaagg
    14581 acattgtatt tgatgggact ttatatcatt tatggtatct acctgcatca attattggtg
    14641 caagtattgc atactttctt gtaaaaagac taggtttaaa gtactcacta gtaatcacta
    14701 ttgttattta tgtaattggt atgtttggtg atagttatta tggtttttta gaaaaaatac
    14761 cactattaaa gaatttatat gggtatattt ttgaagtatc agattataca cgaaatggta
    14821 tattttttgc acctgtattt ttcatacttg gtggaataat atctaataaa tctaattata
    14881 tgtcaactaa aaatagcttg attggatttc ttatatcatt cttacttatg ttatgtgagg
    14941 gaatgttttt acataaacta ggggtacagc gtcatgatag catgtatatt atgttattgc
    15001 catgtatgta tttcttattt acagccttaa catttttgaa aggttctcga gctaggttat
    15061 tgcgaacatc atcattaatt atttatatta tacatcctat gatgattgtt gttattcgta
    15121 tgttttctaa aatattcgga atacaaactg tcttggttga caatagcctt attcattata
    15181 tagtggtaag tatagcatct tttatagctt ctataattat tatattgatt cttaaacctc
    15241 taaaaaaaga cttgaaagga gaacataagg taaataccaa tagagcttgg attgaaattg
    15301 atttaaataa tttggaacat aatgtaaaga tgatacaaaa agctatgcca gaagattgtg
    15361 aattgatggc agttgtaaaa gctaatgcct atggtcatag tgcttttgaa gtagcgactt
    15421 gtgcaaacca aataggtgta aaagcatttg cagtagcaac aatagatgag gggattgatt
    15481 tacgtcgata tggaatacta ggagaaatat tgattcttgg atatactaac ccaataaggg
    15541 caaaggaact tcataaatac aatcttacac agagtgttat tgaccttaat catgctatct
    15601 ctttaaacaa acagaaatac aacataaaat cacacattaa aattgataca ggtatgcaca
    15661 gactgggttt tgatgttaat gatgtgaggt caattttaaa ggcatttaaa ttaaaatact
    15721 tagatatatg tggcatattt acacacttgt gtgtttcaga tagtctgaaa gatgaagatg
    15781 tagactttac aaataaacaa attgaatgtt tttataagtt aattgatttt ctgttaaaaa
    15841 aaggtataaa aattcctaaa gtacatattc aaagtagtta tggttttttt aattatccca
    15901 atcttaagtg taattatgta agaattggaa ttgcattata cgggatatta agttctccaa
    15961 atgatacgac taaattgcaa cttgatttac gacctgtttt atccttaaaa tcacaagtaa
    16021 ttcttattag aaaaatacaa aaagatgata gttttggata tggaagagtc tttattgcaa
    16081 gcagagatag cgtaattgct atattatcta ttggctatgc cgatggtata cctagaaatt
    16141 tatcctgtgg aaaaagttac gtaataataa atggttgtag agcagcaata gtgggtcgaa
    16201 tttgcatgga ccaacttgct gttgatatta cagatatacc taatgtagaa gttggtaata
    16261 cggcaataat aataggaaga gataatttat ctgaattatc tgcttctgaa gttgcaaata
    16321 actcatgtag tatatcgaat gaattattga gcagagtagg aagaaggtta aatgttataa
    16381 agaagtaact caattaaata gtaatatttg ttgtactgtg taatttattt tactctgact
    16441 agacattttt agtaatatta tgtctaatat atatttttta taacttacat gacaatttaa
    16501 gttataaaaa ggtgatgttt cagattttta ttttgaaaca tcaccttttt tgttataata
    16561 tataataaaa taattatacc ttaactgtaa acttatatag attatttact ttttaatatt
    16621 agattcattt tttgagattg gtatataata aacatataga gtatataata atagttaaag
    16681 ttaaaaaagg ggaaaagcaa tatgcagtat atacaagaac tacttgattt gactcaaaat
    16741 tattgggtgt tagccacaat aatcggctta ttaagtgcat ttatagaaag ctttatacca
    16801 gccttaccac ttgttgctat agttacagca aatgctgcaa tacaaggatt atttattgga
    16861 tgtttgttat catggattgg ctcaggactt gggacaactt cattattctt attaataagc
    16921 agatttaatg atagtaagct ttttaataag ttgagaaata gtaaaactga aaaagcaata
    16981 agttggatgg ataaacaggg atttaagtta ttatttatag cgtatgcctg tccatttatg
    17041 cccggttgtt tagttactat cgcatcagct tttggtaaaa aagatttaaa agattttgtg
    17101 ccagcaatgt tggcaggaaa atttgtaatg tttatagtta taagttacgt ggcaagtgat
    17161 atagaaggtt ttataacaag tcctttaaag atagcatcat ttatattatt ggtgtttttg
    17221 tcatggaaga ttggaaatag agtaaataaa aatcttgaaa atcataatta tgatttccat
    17281 cataaaaaac atcacaatga taaagatgat aaaatgattt agcttgtacg aaataaaacg
    17341 tatcttaaaa tgatttagta ctaaattatt ttaagatacg ttttattttt tgtattaagg
    17401 tacaaaattt ttagttcttt tgtaaactaa aatatataaa acttatttat acttagttca
    17461 aaatattgtt atttattttt tctacaacta taataaaata taaaattgat atccaatcaa
    17521 aaaaataact atgaaattta atagcttaga tatgaatttt tctgtttttg agttagtttt
    17581 tataggtagt aaagaaatgt ttatggtaat gggataaaac aattcaatac cttctttagt
    17641 aataaggtca agacacaagt gagatagata tcctattata aacccactgg acaaacatga
    17701 gaaaactata ttattgttag tgaagattgt cagagattta aaaaaactat aaataagtaa
    17761 taaggcaatt agactgtgag taaaccctct atgtctaaac ctacttccaa ataatttgta
    17821 tattaacata aattttttac ttatgtaaga acctctcata tctatatctg gaaataaaga
    17881 acctaaatat gcaaaataaa tataaattat aattaatact attttatatg caatatcgta
    17941 tttaactagg tatagattgt ttataaaggg gagtatcaaa agtgcgaata tataacctcc
    18001 cctttcatgt gtttctttta tcatataaaa atcctcctga atcgtcacta taaacattat
    18061 attggtaaat ttagactatc ttttattata ttatatagca aacataagtt tttttcaaaa
    18121 ggattttaat atttaattaa tcttgagatt ttaaattttt gtaattttct aaagcaccat
    18181 tccaatttac tacattaaac cagttgtcaa tgtattcatt tcttctattt tgatatttta
    18241 aatagtaagc atgctcccaa acatcaagtc ctattatagg agttaggttt ttacttacag
    18301 ggctatcctg atttggagta gtcataatag ataatttgcc atctttagta gctacaagcc
    18361 aagcccaacc agaaccaaag acatctaaag cagatttttg gaactcttgc ttaaattttt
    18421 caaaagaacc aaagtctcta tcaatagctt cttttaaaga ttcagaaggt atggtttttt
    18481 ctggcgtcat tatatcaaaa aagaatttat gattataagc tccacctgca ttatttctta
    18541 cagttgtagc aatatcttta ggtaaagaat ctaaattttg caataattca cataaagaat
    18601 aattataaag ctcaggatat ttttcaagag cagcatttaa tttatcaaca taagcttgat
    18661 aatgcttatc atgatgcagt ttcattgttt ctttatctat ataaggttca agtgcatcat
    18721 atgcataagg taatggttta accttaaatt tgttattttc aggtgtaaaa gcaaatgaag
    18781 ttatgcactg tgagattata aataaagaca taataactgg tattaatatt tttttcttca
    18841 taaaaatcac ctcctaatat agtatttcta gaaataaaaa aaatatgaaa tattaacaga
    18901 taatttataa gaatttaata gcaatttcat tttaaattga ataagtttta aagccaaaga
    18961 caaaactatg aaatatagaa taagactaaa ggacagaaag gaattttgat tatatggacg
    19021 gcaatatttc aatttattat aaaggtgata tatctaaaaa agaagatatt aaatttaaaa
    19081 taaaagaatc tgtaaataat acaagacttt ctagtagaat agagtataag gatgaggaaa
    19141 aaacttttga ttttgaaaga tttaatgtaa ttgatgctat ttatggaaat aaaccatttg
    19201 aaaaagatgg aaaagttatt gtttttaatg gaaatatata taactatcat gaaataaaag
    19261 aagaattaat taaaaaagga cacaatttta ctacaaatga tgatattgaa gtcttattag
    19321 catcttatat agaatttggt aagaattgtg tacataagat taaaggaatg ttcaacttta
    19381 taatctatga tagagaaaat gaaagtatat ttggagcaag agatttattt gggataaaac
    19441 cactttatta tataaataag gaaaatgcaa taattttttc ctcagagtat aagtttttac
    19501 ttgaatatat gaaaaattta aatataaatg aaagaagctt acaaagttat ttttcatttc
    19561 aatatgtact tcctgaagat actatgatac aaggaataag gctgatacca gcaggtcact
    19621 attttagggt agaaaatggt atactatctt taaagagata taataaactt gagtttagaa
    19681 gtagtacaaa atttttttat actaaaaatc acttaggcaa tagagatgtg aatgaggatg
    19741 atataagaaa tatagtagta gattcaatag taactcatat ggaagaggag aaagaaattg
    19801 gaacattttt gtctggtgga atagattcat ctattataac tactgtggct tcacaaatta
    19861 atccaaatat aaaatctttt tctgcaggct ttagtgtcaa aggatatagt gaattagaag
    19921 tagcaaagaa aacagctgat aagttaggta tagaaaatat ccagattaat ataacacaag
    19981 atgaatatat aaaatcatta ccgaatgtaa tttattcttt ggatgaccct atagcagacc
    20041 cttcagaagt aggtctttat ttcttaatta aagaggcagg taaacatgtt aaagtagcat
    20101 tgtctggaga aggagcagat gaattatttg gaggatataa tatatataaa gagtatagta
    20161 ctatgaaatc agttgtcaat tcacctactt atattaaaag tatattagga agagtttcag
    20221 aacttatgcc aaacataaaa ggaagaaatt atctttatag agctacaaca ccattagaaa
    20281 aaagatatat aggaaatgca aaagtttttg aaaacagcga agtaaaaaga ttctttttta
    20341 agtataagga aaagaatata tatgaatacc tgttgtctaa tttgtataga gatgcacaaa
    20401 aaaataatta cgattatata agtaaaatgc aacatataga tgtgaataca tggcttcaag
    20461 gcgatatact tcaaaaaatt agcaaacttt ctacagctga gcaggttgaa cttagagtac
    20521 catttttata taaagatgta tttgatgtcg caaaaaattt aagaatggag caaaaaataa
    20581 ataagaataa tacaaaagtt ttacttagag aggcgtttag agaaatagtc ccagaacatg
    20641 ttgttcaaag gaaaaaatta ggatttccaa ctccaataag agtttggtta aaagattctc
    20701 taggggatat tgtaaaggaa actatttata attcaaatgt agatgaattt atagataaaa
    20761 aatatgcaat aaaactttta gatacgcatc ttaaaggtca tagagataat tcgagaaaaa
    20821 tatggactat atttacattt tgtctatggc atcaattatt tattgagcat aaaaatgtcg
    20881 agtattaata cttttttcaa tattaatcag agggcaaaag catgcaatgt tttcaccctc
    20941 ttgattatta tggaatagga taagtagaat tttgattgat tagtttacta tctcaataaa
    21001 attattggca aatattttga caagactact ttcaacagct aaatttaagt tttgtccatc
    21061 atcatatcca gcggaaatca atcctagtaa gtttccaaac atatctaaaa gagctcctcc
    21121 tgaactacca ctagagattg gagctgtaaa ttgtatcatt tgaaccgttt caaaatcacg
    21181 aaaagctgaa ataattccat ctgaaactgt attaaaaaga cctagagggc ttccaattgc
    21241 aactattttt tgacctctca caggtttttt actgacttta acaggtattg gcttgcattt
    21301 tctatcaacc tttatcacag ctaaatcata atctgaatgg tattttataa tttggtaaga
    21361 tgtataaact ttatcatcat tttcaaatct aactaaaaat gaatacccat cattgactac
    21421 atgaagattc gtaagtatat aaccttcatt atttattact actccagaac cgctcttaaa
    21481 cggtttattt tcgttattgc acacaacaat cataacaaca gaagctgata actttgcaag
    21541 gtcttcataa gaaagttcta cttcctcatc ttgtacaatt tttttagatg ttagatttgt
    21601 gttattaagt gtatttttag agttaggttt attcgtagta ggagaagtct tattggtatt
    21661 ttcactgtaa tttatatttg taatatgcct ttcaaaaggt atttctaata tatttggagt
    21721 cttcctagaa agttcaaata gagtagaaaa ttttgaacat tcaggatata aatcaagaat
    21781 atctttattt ggatttatat ataaaatatc acacccaagt tgtgataaaa aatataagaa
    21841 aaaaagttct tgccttttaa tatttccaaa gtatactatc tttggtgaaa tagtagtctt
    21901 caccttgtta taaaataatt taggtagaaa atagtctatc caacacaaaa gtttaactgc
    21961 aaagtttttg atgatagagg atgtacaatt tggcatactt gtggaaaata aatctaaagt
    22021 atttttaaat gcaatctttt tagtccaatt taaggtgtca ttttctattt tacatggaaa
    22081 gtcgatatta tataaatccc aactgttaaa cttagaacta ttataaatat taaaaatttt
    22141 aagcatctta tctgtttgtt ctttgtcaaa atttattttt agattgttta atctaatata
    22201 gggaattgta ggattattaa aaaaataagt atctatattt ttaatttttt ctatgtattt
    22261 atcaattgaa tcatcaacac ctatatatct tgtaaagtag acttctttaa tatatgaaga
    22321 actcttattt ttataggtag tatcagatat aaattcaatt agaggttcag tagacttttt
    22381 tattgaaatc tttaatggtt taatagtaca aatcatattt tttctcctat aataagatga
    22441 tataatctat tataaaacaa cttaaaacaa tatagtacaa taattttgta gtttcaaaat
    22501 aaaatatgta cttgtttata taaatgatat ataattacaa taaaattgcc gaaaagccct
    22561 ctcctttagg tgtagggatg aaaggtaagg tcttaatata aaaaaagtta gaataatgct
    22621 tgtaatctaa taccgctact gataccctat atttaggagg tgttagtttt tatgtataaa
    22681 tctaacaaaa atatagttta tgattgcaaa tatcatattg tattttgccc taagtatcgt
    22741 aaacctgttt tagttggcga agttgaaaag atgttaaaag aaatactacc atataaagca
    22801 gatgaacttg gagcagaaat aatagaaatg gaaactgata aagaacatgt gcacttatta
    22861 atatcttgtg accctcaata tggaattcat aaagtagtaa aaggtttaaa aggctttagt
    22921 tcgagagtat taagagagaa ctttccacat ttaaagtcta gtatgcctag catgtggact
    22981 aatagctatt ttgtaggtac tgttggttct gtgagtttag aagtagttaa acaatatata
    23041 gaaaatcaac aagttaggac aaagaaatga taaaaactca tagagtgaaa ttaaacctaa
    23101 ctagaacaca atttgaatta gtaagggaaa agcaaatgga aagtgctaac tgttggaact
    23161 acatagttaa cttatctaaa gaatactatt ttgaacataa acaatggatt aaaaagaatg
    23221 atatacaaaa gttaatcaaa ggtaagtaca atcttcatag tcaaactatt caagctatat
    23281 cagataaatt tgatgcaaat agaaagacta tatcagaatt aagaaaaaaa ggtaatacta
    23341 aagcaaaata tccatacaag actaagaaat tttatataat accttttaaa gctagtgcta
    23401 ttaatagaaa tgctaaaggc aacttaaaat tatcaatgtc aaaaggcagg tatttagaat
    23461 tagattttaa tgttgagaat ataaaaactg ctgaaatagt atggcgaaat ggatattatt
    23521 tatactacac ttttgacaat gaattaaatg gagttgtagc caaaggcact aataccgtag
    23581 gtgtagactt aggggaaata cattcgatag ctagtgtaac aaataaaggt gtagggctta
    23641 ttctatctaa tagagaaggc agaagtatta aacaatttag aaataagatg tatgcttata
    23701 tatctaaaag attaagtaaa tgtaaaaaag gtagtagaca atcaaagaag ttatggagat
    23761 taaaaaataa gataagaagt aaaacagata atcagttaat gaatttatat catcaaacaa
    23821 ctagaaagtt tatagacttt tgtgtagagc agaaggtatg tgaaatagtt cttggggata
    23881 taaaaggggt tgaaaaagat actaagaaaa agaaaagatt aaacagagtt aatagacaga
    23941 aaatatctca aatggagtat ggtcgaataa aggactatat aaaatataaa gcaaaagagc
    24001 aaggtattga agttaagtta gttaaagaaa actacacttc tcaaacttgc ccaaagtgtt
    24061 ctaaaaaaca caaaccaact ggtagaactt atagttgtac ttgtggttat gaaactcata
    24121 gagatatagt tggtgcttgg aatattttaa ataaaaagca taaatatggt ttagtagatt
    24181 ttagaataaa tcataagcaa ccaataaatt taaaagtatc taccgtttga gccatgtgtg
    24241 ggcgaataac tttaaggtag tagtggcgaa gacaccgtcc gaagtagctt ggctttgtaa
    24301 ccacctctgt tgtactgttt aagtataaat aagtgtgtta gccaccaaga atccccttgc
    24361 tttagctatg gggagtgtgt caataaaata ctttaatgaa aaatagctaa ctttaattgt
    24421 aggatattct taatatattt gaaataaata aaaatattga aggatataat attcaactgg
    24481 tatataaata ataaatgata gttaaatttt accttagagg ctaattaggt gtttagtcaa
    24541 agctaatgcc tttagaatac aaatgtattc taaaggcatt tttactatgt attttcattt
    24601 atattactaa acattatcta tttttatata catttctatg tattttattt tcatcaaatc
    24661 ggtctataaa ctcatttttt tcttcactat atccaataga tataagtgca taaggaacta
    24721 attttaatgg taagtctaaa gtttgtctaa ctttatttac cactttattt ttaggaaata
    24781 ctcctgccca acaagcagct agaccttgat tagtaacttc taataataaa ttttgtgtgc
    24841 aagcacctaa atcttgtatc catttaccag gttttaagaa tttatctcta tttccaagca
    24901 ctactataca taatggtgca aattctatat gctttgctct atgctgtgac tttgagagct
    24961 gtttcagcag ttccttatca tctactataa taaattccca aggttgagca ttttttgatg
    25021 aaggtgcttg catagctgat tttagtattt cagttatttt atcttcttct atatttttat
    25081 ctatatatgt tcttattgaa cgtctatttt ttataacttc taacatacag attctccttt
    25141 aaataaaatt atttctattt atataatatc attactttaa attttagcta ttacttatat
    25201 aaagaataaa ctttgtgttg gttttatcta agtaaaagta acattcagaa ctaaaaaaca
    25261 agactataaa tccaaagtat taattaaaaa agaagtaata aaaaataata tacaagattt
    25321 aaaaaagagt attgggctta aaatttaatt agaaaaccaa ttttgagata atctgttttt
    25381 tattttaaca aaaaaacata aataaagttc gatacgtagc gaatgaaaaa attacaagaa
    25441 atattttttt taaaaaattt caaaaaagag ttgataatat atgtatatta atataaaatt
    25501 taaggtgtat aattcgtata ataatacgaa tgatttgtag tgtaaaataa cttataaacg
    25561 gagaggggaa gtctaatgaa agtagcagta gttatgggtt caaaatcaga ttatccaaaa
    25621 ttagaagaag ggataaaact gcttgaaaaa tatggaatag aagttgtagc aagagcatta
    25681 tcagctcata gaacaccaga acaactttca atattcctaa aagaaataga agatgatact
    25741 gatgtaataa tagcagcagc aggaaaagca gcacacttac caggtgtaat agcttcacaa
    25801 acattaattc ctgtaatagg attacctatt aaatcatcaa ctatggatgg actagactca
    25861 cttttatcaa tagttcaaat gccaaaagga atcccagttg caacagttac aatagactta
    25921 ggtttaaacg cagctttatt ggcattacaa ataatgactt taaaataccc aaaattaaaa
    25981 gaggatttga aatcatatag agaagagatg gcacaaaagg tgttagaaga cgacaataat
    26041 ttaagggggt agcagaaatg ttattatatg aaggaaaagc aaaacaagta tattctacag
    26101 ataatgaaaa tgaatatgtt gtttattata aagatgatgc aacagcattt aatggagaaa
    26161 aaaaagcaga aatatcttca aaaggtatac taaataataa gatatcaaca ataatctttg
    26221 aaatgttaaa agaaaataat ataaatactc actttataaa aagtttatca gatagagaaa
    26281 tgttagttaa aaaagtagag attttaccat tagaagtaat agtaagaaat attgctgctg
    26341 gttctatctg taaaagagtt ggtcttgaag aaggtgtagt tttcgatgag ccaatttttg
    26401 aaataagcta caaaaatgat gcttatggtg acccaatgct aaatgatgat tatgcagtgg
    26461 caatgaagtt agcaactaga gaagagttaa aattcttaag agaagaaact ttaaaaataa
    26521 atgagttact aaaagcattt ttcttaaaat taaacctaaa gttagttgac tttaaaatag
    26581 aatttggtaa ggattctgaa ggaaatataa tattggcaga tgaagtatca ccagacactt
    26641 gtagactttg ggatgtaaat acaaatgaaa agttagataa ggacagattt agaaaagacc
    26701 ttggagacct tgtagaaggt tatacggaag tactttcaag aatgaataat aaataggagg
    26761 caaatgtatg tgtggagttt tagggattta ctctaataaa gatgtaacta aagaactata
    26821 ttattcttta tattctatgc aacacagggg gcaagaaagc tgtggtttag ctcttttaga
    26881 tgatggagaa attaagtaca aaaaagatat gggattagtt ggagatgttt ttaaggaaaa
    26941 tgaattatct aagttaaaag gaaatatagg gattggacat gttagatatt caacagctgg
    27001 aggaagtcat gtttctaatt gtcaaccttt agttggaagt tgtagaaaaa gacaattagc
    27061 catagctcat aatggaaatc tagttaatgc aaattattta aaagatatgc tagaagaaga
    27121 tggatatatg ttccaaacta attcagatac agaagtgatt ttatatatac ttgctagata
    27181 ttacaaaggg gatatagtag aaagtttaaa agtgacaatg gattatataa aaggtgcata
    27241 tgctcttgta ataatgagtc aagaagaatt ggttgcagtt agagacccac atggattcag
    27301 acctcttgta cttggtaaaa agggtgatga atatatattt gcatcagaaa attgtgcaat
    27361 agatatactt ggcggagaag ttataagaga tgtagagcca ggagagataa tagtagtcaa
    27421 agatggagaa ctaaaatcat atttttattc agaaaattat aaaccagtta agaaaagttg
    27481 tatatttgaa cacatatact ttgcaagaaa tgatgcaact atagacaatg taaatgcata
    27541 tgaatttaga attaaatgtg gtgagagatt agctcagaat gaaactgtaa aggcagatat
    27601 ggtagttcca gttccagatt caggttggcc aggagctatt ggttatgcaa atgctagtgg
    27661 attaaaaata agtgaaggct tagttaaaaa tagatatgta ggaagaacat ttataaaacc
    27721 tacacaagaa gaaagagaaa tagcagtaaa aataaaatta aatcctcttt caacaataat
    27781 aaaaggaaaa tctataattt tagtagacga ctcaattgta agaggaacta catctaaaca
    27841 attagtaaaa tctttaagag aagcaggtgc aaaagaaatt catcttagaa taacttctcc
    27901 tccagtagct tactcttgtt actatggaat agatactcca aatcgctcta aattaattgc
    27961 atcaagtaac aacgtagaag aaatgagaga atatattgga tgtgatagtt taaaattcct
    28021 agatatagaa ggaatgttag atgcaacaga acataagtct actttctgta aagcttgttt
    28081 tgatggagaa tacccagtta agaaaattga taaggaggaa ctactttcat gttaacatat
    28141 aaagaatcag gtgtagatat agatgaagga aatagagcag tagaccttat aaaaggtaaa
    28201 ataaaaggaa cttatgatgg aaatgtagtt ggagatttag gtaacttcag tggattatac
    28261 agtttaaaag attttgtagg tatgaaagaa ccagttttgc ttgcatctac agatggtgtt
    28321 gggactaagt taaaaatagc tcagatgatg gacaagcatg atactgttgg aatagattta
    28381 gttgcaatgt gcgtgaatga tttaatttgt caaggagcaa aaccattatt cttccttgac
    28441 tatatagctc ttgggaaatt agtgcctgag catatagaaa aaatagttgg tggaattgca
    28501 gatggttgca aaatgtctgg ttgtgcacta attggtggag aaactgctga aatgcctgga
    28561 atgtatggag aagatgacta tgatttagca ggattttctg tgggaatagc agacaaagaa
    28621 aagattgttt ctggaaacaa tgttaaatca ggagatgtat tggttggtat atcttcaagt
    28681 ggagtacaca gcaatggatt ttcttttata agaaagatat ttttagaaac ttacaattat
    28741 aaaatggaac gatatgttga agaactagga atgacagttg gagaagcact tttaacacca
    28801 actaaaatat atgttaaatt agctttagat gtattagcta aacatgacat aaaagctgta
    28861 gctcacataa ctggtggagg gcttatagaa aatataacaa gagttatacc taaaggatta
    28921 ggactagata tcaataaaaa atcttgggag aagcctccta tatttaaaat gatagaaggt
    28981 tttaatgctg ttgatgagag agaacttcat aagagtttta acatgggtat tgggctagtt
    29041 ttaatagtag ataaagaaaa tgctgatgat gttgtaaact ttataaataa tagagaaaat
    29101 gacaatgctg attatgtaga taaaaaatat agtgaattat tagaagataa agcttatata
    29161 attggtgaag tagtagatag tcatgaaggt gtagaattat gctaaatata ggagttttaa
    29221 tatctggtgg gggaacaaat ttacaagcag ttatagatgg tactgagtct ggagaaataa
    29281 aaggtcaggt taaagtagtt atctcaagta agcaaggtgc ttatgggcta gagagagcta
    29341 aaaatcataa cataaaagca atttgtgaaa ctgatgaaga caagataata gaaattctta
    29401 aggaaaataa aatagattta gtagttttgg ctggttattt aaaaataatc agcccaaagc
    29461 tggttaatga gtttagaaac aaaatgataa acatacatcc atcattaatt ccttcatttt
    29521 gtggagctgg attctatgga gaaaaagttc atcaaggtgt tatagattac ggagctaaag
    29581 taactggtgc tacagttcat tttgttgatg aaggtgctga tactggacca atcataatgc
    29641 aagatgtagt taaggtaaat caagatgatg atgcaaagac acttgcaaaa agagtgttag
    29701 aagttgaaca taggatttta aaagaaagta taagtctttt ttgtgaaaat aaattaaaac
    29761 ttcaaggtag gagagtgttt ataaatgagt aagagagctt taataagtgt aactgacaag
    29821 actggtgtag tggaatttgc taaagagtta aataaattag attatgaaat tatatctaca
    29881 ggaaatacat ttaaaacatt aaaagaaaat ggtgttaatg taatgcaagt tgaagatgtt
    29941 acaaattttc cagaaatatt agatggaaga gtaaaaacat taaatccata tatacatggt
    30001 ggtatacttt ataaaagaga taaagaatct catgtagaaa ctgtaaatga acataaaata
    30061 cattcaatag atttagtagc tgtaaatcta tatgattttg aaggaacttt aaaagctgga
    30121 aaaagtcatg atgaaataat tgaaaatata gatattggtg gaccatctat gatacgttct
    30181 gctgccaaaa actataagga tgtaatagta gtagtagata taaaagatta tgattctata
    30241 atagaaaaat taaaaacaga tacaatgaca ttagaagaca gaaaaaaatt atcatataaa
    30301 gctttctcaa ctacaggaag atatgatgcg ttaatatcta gttattttgc tggagaagtt
    30361 ggagatacgt atcctgacat attaaattta actttccaaa aagaacaaac tttaagatat
    30421 ggagaaaatc cacatcaaaa tggtttctta tattcacagt caaatgcaaa aaatccaatc
    30481 ttaaattatg agcaattagg cggtaaagaa ctttctttta acaacttaaa tgatttacat
    30541 ggatgtttag aagtaatgag agaatttaaa gatagtgaag aagtagtttc agtagctata
    30601 aaacatgcta attcatgtgg ggtaggttta ggaaaagatg cttttgaagc atatacaaaa
    30661 tgttatgaag cggataaggt ttcaatattt ggaggaatag taggaataac ttctactata
    30721 gataaagcta cagcagagaa attaaatgaa atattcttag aaatagtagt agcatatgat
    30781 tttgaaccag aagctttaga gatacttaaa caaaagaaaa atctaagaat attaaaatta
    30841 gctaaaatag aaaatagttt acaaccatat gaaatgaaat atttagatgg aaaattattg
    30901 atacaagata gaaacaatat attagcagaa aaaagtgaaa atgtaacaaa ggaaaaacca
    30961 acagatgcac aacttaagga catggaattt ggtatgagag tagtaaaaaa tatgaaatca
    31021 aatgcaattg caatagtaaa aaatggacaa actctagctt taggttgtgg acaaacatca
    31081 agaatttggg cattaaaaaa tgctcttgaa aataacaaag ataaagattt tacaggagct
    31141 gttttagcgt cagacgcatt tttcccattt gatgattgtg taacattagc tcatgaatat
    31201 ggaatatcag cagtagttca accaggtggc tctataaaag ataaagattc aatagaagct
    31261 tgtgacaagt atgatatggt tatggtattt acaggaataa gacacttcaa acactaagga
    31321 ggatattatg aagatattgg ttgtaggcgg tggcggaaga gagcatgcta tatgctggaa
    31381 actaagcaaa gaaaaaaatg tagaaaaaat ttattgtgca ccaggtaatg caggaattgc
    31441 aaacgtagca gaatgtgtaa atataggtga tactaatata gaagaacttt taaaatttgc
    31501 caaagaaaat gaaataggtc tgacaatagt aggaccagaa gtaccactag ttatgggaat
    31561 agtagatgag tttgaaaaag aaggattaag agtatttgga cctaataaaa aatgtgctca
    31621 acttgaagga agtaaagctt tttcaaaaga atttatgata aaacataaca tacctactgc
    31681 aaaatataaa gaatatacaa acttagaaga agctatatca gaaatagata gttttggata
    31741 tccagtagta ataaaagcgg acggattagc tgctggaaaa ggtgttgtaa tacctgaaaa
    31801 tagagaagat gctatagcaa ctttaaaaga aatgatgtca gataagaagt ttggagctgc
    31861 tggagataaa atagtaattg aagagttttt aaaaggaata gaaacttcaa ttctagcatt
    31921 tgtagataat gatacaatag ttcctatggc aagtgcaaaa gaccataaaa aagtaaacaa
    31981 ctatgagcaa ggtccaaaca ctgggggaat gggaactttt tcacctagtg aaatatatac
    32041 agaagaatta gcaaataaag taaaagagac agtattagaa aaaactttag aaggcttcaa
    32101 aaaagatgga cttaatttta aaggtatttt atttgttggt cttatgataa ctgaagatgg
    32161 agaaaaagta cttgaatata atgtaagatt tggagaccct gagacacaat ctgttttatt
    32221 tagattagaa acagatttac atgagataat ggaagctata ctagataata agttaaaaga
    32281 tatagaaata aactatagtg atgatgaagc tgtatgtgtt atgcttacat caggagggta
    32341 tccagacagt tatgaaaaag ggaaaattat aactggtctt gaaaacttgg atgatgatat
    32401 agtagtattc catagtggca ctaagatgtt tgatggtaat ttggttacca atggaggaag
    32461 agtaattggt ataactgcaa agtcaactac agttaaggat gcagcagaaa aagtttatga
    32521 aaacataaag aagataaact ttgaaggaat gcactataga acagacatag gaagataatt
    32581 tttctaaaat ggaggataag gtatgttgaa tactgaaaat aaagactcaa tggttagaag
    32641 agtattagtt gaaaaaagag aaggttttga ccttgaggct aaagctttaa aaaaagactt
    32701 agtagaaagt ttacacatag ataatataga aaatttaaga atattaaata gatatgatgt
    32761 agaaggaata tcagaagaag tttatgaaaa tgcagcaaag acaatattct ctgaaccaaa
    32821 tttagatgta gtatattatg aagaaatacc aaaattaaat gatgaaagag tatttgcaat
    32881 agaatttctt cctggtcaat acgaccaaag aggtgattgg gcagctcaat gtgtacaaat
    32941 tgtaaatcaa gggataagac ctgctattaa tacagcaaaa gtttatatat tatcaggcaa
    33001 aataactgat gaagagtttt ctaaaataaa agattactgt ataaatccag tagatagtag
    33061 agaagcatct ttagaaaaac cagaaacgtt aaaaatggaa actgaaatac caacaacagt
    33121 tgaagtatta gatggattta tagatttaga tgaaaatgga ttaaaaacat ttgtaagtga
    33181 aaaaggatta gcaatgactt taggagactt acaacacgtt caaaaatact ttaaagatac
    33241 agaaaagaga aatccaacta taacagaaat aaaagtatta gatacttatt ggtctgatca
    33301 ttgtagacat actactttta tgactgaaat agaaaatgta aagatagaag atggtaagtt
    33361 taatgatata gtaaaagaag cgtatcaaat gtatcttaac tcaagagaca atgtatatgt
    33421 gaacagacat aaagatatat gtttaatgga tatagccact gttgcagtaa aagaattaaa
    33481 gaaaaatggg aaattaaatg acctagatga aagtgaagaa ataaatgcat gtagtataaa
    33541 cgtagatgtt gaagttgatg gtaagatgga aaaatatcta gtaatgttta aaaatgaaac
    33601 tcacaaccat ccaactgaaa tagaaccatt tggtggagca gctacttgtt taggaggagc
    33661 tataagagac ccattatcag gaagaagtta tgtttatcaa gcaatgcgtg ttacaggaag
    33721 tgctgaccca agaacgactt tagaagatac tttacctgga aaacttatgc aaagaaaaat
    33781 aactacagaa gctgctcatg gatatagttc atatggtaac caaataggtc ttacaactgg
    33841 acaagttgca gaagtatatg atgaaaactt tgttgcaaag agaatggaaa taggtgcagt
    33901 tatagcagca gcaccaaaag agaatgtagt aagagaaaga cctgaagcag gagatgtaat
    33961 cgttcttctt ggaggaaaaa caggaagaga tggctgtgga ggagcaactg gttcatctaa
    34021 agaacatagt gaagagtcaa tcttaacttg tagtgcagaa gttcaaaaag gagatgctcc
    34081 taacgaaaga aaaatacaaa gattctttag aaataaagaa gttgctcaaa tgataaaaag
    34141 atgtaatgat tttggagcag gtggagtttg tgttgctata ggagagattg ctgatagctt
    34201 agatataaac ttagacttag ttcctaaaaa atatgatgga cttgatggaa ctgagcttgc
    34261 aatttcagag tcacaagagc gtatggcagt agccataaaa aaagaaaata aagataaatt
    34321 tatacaatta gcagtagaag aaaacttaga agctacgcat gtagctacag taacagatac
    34381 aggatattta agaatgttct ggaatggaaa agcaattgta gatataaata gagagttttt
    34441 agatacaaac ggagtaaaac aaactactga tgttcatgtt actaaagtag atgaagaaaa
    34501 tacattcttt agctctaatg aaatagtaaa agatgttaag tgtgcaagta tgaaagacaa
    34561 gtttacaaaa gtactatctg accttaatgt ttgttctcaa aaaggattag tagagatgtt
    34621 tgataataca attggtggta atacagtact tatgccattt ggaggaaagt atcaagcgac
    34681 tccaacacaa ggtatggttg ctaagatacc agtacttgga ggagaaacta atacttctac
    34741 aataatgact tatggataca atccaaaggt aggaaaatgg agcccattcc atggtgcctt
    34801 gtatgcagta gtagaatctg tgtgtaaatt ggttgctatt ggaggaaatt atagtacaac
    34861 aagacttaca ttccaagagt attttgaaaa acttggtaac aatccagaaa aatggggtaa
    34921 accattctca gcacttttag gagcatttta tgcacaaagt aaatttgaga tacctgctat
    34981 aggtggaaaa gacagtatgt ctggtacatt taaagatatt gaagttccac caacattagt
    35041 ttcatttgct gttgacacag tagatgcgaa gaaagtagta tctccagaat ttaaaaaagc
    35101 agactcaaaa gtagtaatgt tatgtgtaaa caaggcagaa aatgatgttg tagattttga
    35161 ggaattaaag agaaacttag ataaagtaag agaacttata catggaaata aagttttatc
    35221 aacatatgca ttaggatttg caggtgtagg tgaagcaata agtaaaatgg cttttggtaa
    35281 taaaatagga tttaagttta gtgaagaggc tgaaaaagca tttacagatg ataaattatt
    35341 tgaggctagt tatggaaata tagtacttga attagcaaat gatgatttaa gtatgttaga
    35401 aggatacaat tatgttgtgc ttggaagtac agttaaagaa actagtatat ttatcaaagg
    35461 tgaagaactt gcattagatg aattatataa agcacattgt agtactttag agcctatatt
    35521 cccaactaaa acagaagaag taaaatcaaa gatagaaact ataagttata tatcacaagg
    35581 agaagctaaa aaatcatcat taagtatagc tactccaaga gtatttatac cagcattccc
    35641 tggaacaaac tgtgaatatg actctgcaag agcatttgaa agagcaggag ctaatgcaag
    35701 tataagagta tttaagaatt taacttataa agacatagaa gattctatag atacaatagt
    35761 aaacgaaata aaatcttctc aaataataat gttaccaggt ggatttagtg ctggtgatga
    35821 gccagatggt tctggtaaat ttatagctac tgtatttaga aatcctagag tgcaagaagc
    35881 tataaatgaa tttttaactc aaaaagatgg actaatgtta ggtatctgta atggattcca
    35941 agtattaatt aaattagggt tagttccata tggagaaata agagttccaa gtgaaagtgc
    36001 tccaacactt acttacaata atattggtcg ccatcaagct aagattgcta gaactagaat
    36061 ttcatctaat aaatctcctt ggttagctca aactaatgtt ggagatattc ataatatagc
    36121 aatttctcat ggagaaggta agtttgttgc cagtgaagat gttatgagag aattaattgc
    36181 taatggacaa gtagcaactc aatatgttga ctttaataat gaagctactt atgatattga
    36241 gtttaatcca aatggttcat tctatgctgt tgaaggtata actagtgctg atggtagagt
    36301 gtttggtaaa atgggacatt ctgaaagaat tggtgaggaa gtatataaga atattatagg
    36361 tgaaaaagac caaaagatat ttgaatctgg agttaaatat tttagataaa gctttgatgt
    36421 ttaattgata gctagaatat ataatttaga tatttagatt taaagagatg taataatatg
    36481 atgataatca tttaatatta catctctttt ttatttatct aagaaataat aagttcaacc
    36541 taagttaaaa tacaagctgt gttataatta attattaagt aaaattgaat atttattgga
    36601 ggacaacata attaatgaaa atattaataa cagggtctaa tggtcaatta ggaaaagaat
    36661 tggttaacca attagaagca atcaatcaaa gtataaacca accaaaatat gttatattag
    36721 ctacaacaag aagtgatttg gacatatcca atcagactaa tgtagataat tttattttgc
    36781 ataataaacc tgatgtagtt gtaaactgtg cagcatatac aaaggttgat gcatgtgaag
    36841 ataatatcga aattgcatac aaaataaatg ctttaggagt gagaaatcta gcaatagcat
    36901 cagaaaaagt taatgctaag cttattcaca tatcaactga ctatgtattc aatggttttt
    36961 ctaaatatcc atatagggaa gacaataaaa ctgaacccaa ttctgtatat ggaaaaagta
    37021 aacttatggg agaaaaattt gttgaacaat tctcacataa gtactttata ttgagaacag
    37081 catggttata tggtaatggg aataattttg taaagaccat gataaaactt tctttagaaa
    37141 ataaagaggt taatgtggtt aatgaccagt ttggaactcc aacaagtaca gtagacttag
    37201 caaaaattat aataaaaatc atggaaacag aacattatgg agtttatcat gctacatgtg
    37261 aaggtgagtg tagttggtat gattttgcca aaaagatatt taaactaaaa aatatagata
    37321 taaaagtaaa tccaattaag agtaacgaat ttaaatgtaa ggctccaaga ccactatatt
    37381 ctgtattgga taattttatg ttgaagttaa ttggtttaaa ttcttttaga aagtgggaag
    37441 aatccattga agaatattta gaaagatatg atataaatga aaagtaaatg tattattttg
    37501 agaaaagaaa ataagatatt ataaaaaata taaatatttc ttttatttat ccgataatca
    37561 taatatgaca aaaacaaatt taaggatgga aaaagatgaa aggaattatt ttagcaggag
    37621 ggtctggtac aagactatat cctataacaa aatgtatatc aaaacaaaca cttccaatat
    37681 acgataaacc aatgatatat taccctatgt cggttcttat gttggcaggg atacaagata
    37741 tattaataat atctacacca agagatataa aagcatttga agaattattt ggagatggaa
    37801 gttcactagg gcttaacata acatatgcaa ttcaggagaa agcaaatgga attgcagaag
    37861 cgtttataat aggagaagaa tttataggaa atgacagagt gtctcttgta ttaggggata
    37921 atatatttta tggatatgga tttagtgaaa ggttggagaa tgcagttaaa agaaaaggag
    37981 caactatatt tgggtatcat gtaagtaatc caaattcgtt tggagttgta gaatttgata
    38041 aggattttaa tgtattgtca atagaagaaa aacctacagt tcctaaatct aattatgcta
    38101 taccaggatt atatttttat gataatgatg ttgtagagat agcaaagcta gttgaaccgt
    38161 cagatagagg tgaattagaa ataacctcta taaacagtga atatctaaaa cgaggaaaac
    38221 taaaagtgga acttctagga agaggtatgg cttggcttga tactggtaca cataaaggtc
    38281 tattggatgc ttctaattat gttgaagtgg ttcaaacaag acagggactg tatatagcat
    38341 gtttagaaga gattgcatat acaaaaggat atataagtag agaacaatta atgaaactag
    38401 ccaagccact gataaaaact gaatatggtc aatatctatt aaaattggct agtgaagata
    38461 tgtaatatgg tagataaaat ttattataaa ttttattaag ggagtttatt ataatgggaa
    38521 aaatcaatgt tataaagact aaaatagaag gattatatat agtcgaacca aatgtatttt
    38581 atgatgaaag aggatatttt atggaaagct ataataaaaa ggattttata gagcagggtc
    38641 ttgatatgtg ttttattcaa gataatgagt ctagctcaag aaaaggcgtt ttaagaggaa
    38701 tgcattttca ggttaaatat cctcaaggaa aattagtcag agttacagag ggagaagttt
    38761 tcgatgttgc agttgattta aggaaagatt cacaaacatt tgggaaatgg gaaggtgtaa
    38821 tattgtctga taagaataaa aaacaatttt atattccaga agggtttgca catggatttt
    38881 tagttttatc agaaaaagca gtatttagtt acaaatgtac aaattattat tacccagaat
    38941 ttgagaatgg ctttatatgg aatgacaagc aaatatctat tgagtggcct ttaaaaggaa
    39001 ttgaagaaat atttttatca gaaaaggaca aaaaacaaaa aagttttaaa gatatttgta
    39061 caagacgtta ataaaaattt attagaatta acatttagga gaaaaaatat gaaaaaaata
    39121 ctgataactg gaggagcagg atttattggg agtaatttta tacattatat gcttaacaag
    39181 tatgtagatt attttattgt taacctagac ttgttgactt atgctggtaa tttagagaca
    39241 ttaatagaaa tacaagacaa ttccaattat aaatttgtta aaggagatat ttcaaatagg
    39301 gagcaggtgt ataagctatt tgaagaagaa aggtttgata tagttgttaa ctttgctgct
    39361 gaatctcatg tagataggtc agttgagaat cctgatttat ttattaaaac aaacattata
    39421 ggaacacaag tacttttaga tgcatctata aaatatggag ttaaaaggta tcatcaaata
    39481 tctacagacg aagtgtatgg tgatttacca attgatagaa aggatttatt ctttacagaa
    39541 caatcttcta tcaatccaag ttctccatat tcagcttcta aagcatcagc agatttattg
    39601 gtaagttctt attatagaac atatggattg ttaacaacta tatctaggtg ttccaacaat
    39661 tatgggccat atcattttcc tgaaaaattg attcctctta tgattttaaa tgctttggaa
    39721 aacaaacaat tgccagtata tgggaatggg gaaaatgtaa gagattggtt acatgtatat
    39781 gaccattgta ctgctataga cttaataata cataaaggaa atatagggga gatttacaat
    39841 ataggaggtc ataatgaaag aagtaatcta gaagtagtaa aaatgatatt aaatctttta
    39901 ggtaaatctg aagagttaat atcctatgta aatgatagac ctggtcatga tttaagatat
    39961 gctattgatg caactaaaat agagaatgag ttaggttgga aggcaaaata tgactttgat
    40021 ttgggtataa aagaaactgt taagtggtat atagaaaatg aatcttggtg gaaagctgtt
    40081 ttatcagtat aactttaaaa tttagaaagg ggcgttttat attgaatgag ataagttcac
    40141 taattaatat attagcattg actcaattat ctggtagtaa tactacaaat caatgtaatt
    40201 gtacatataa taattcatct ggatttgata tgattatgat gaccttgtta aaagcattat
    40261 cacaaaataa tcaacatact tctaatagct acaatttatt gtctaattct gagaatttat
    40321 ttaatgaact tgataatgta gtaaataata ccactagtag atttatagat gttgatacaa
    40381 aagataaaaa tgtaaagttg agaattgaaa atgctgtaaa tcaagcatca aaaaaatata
    40441 acgtagattc aaatcttata aaagcaataa ttaaagttga atcagatttt aatccaaata
    40501 ccgtttcttc tgctggtgct aagggtctta tgcaacttat gccagaaaac tgcagagact
    40561 taggggttac agaccctttt aatatagaac agaatataga tgctggaact agacatatta
    40621 aggaatacat tgatatgttt ggagggagca tagaaatggg attgatggca tataatggtg
    40681 gtcctggaag aatgaaaagt agaggagtag aatcaatctc tgacctgtat aaaatgccaa
    40741 aagaaacaca aaattatatt cctaaggtta tgaaatatta tagagggtag gctttattat
    40801 gggaataaat atagataagc taaacataag tccaagtata aatatggagg ttaaaaaact
    40861 aaaagagagt aataaatttt ctgacaaatt aaactcttta aaacaatctt cttcattgga
    40921 agatataaaa cgaaatttgg aaagtgtaaa aaaggcagga gaaaggcttg tacttactca
    40981 aaactatggc gatattagta tatataaaaa tgcagtaaaa gaatacctaa aatctgttgt
    41041 agataatatg tattcacttg ataaaaatag tagcttttgg gagcatcagt attataagaa
    41101 tgtaaagatt gttgatagta aacttgagga tatgactagt aagttaatta gtgaagaaaa
    41161 agaaaacata gatattgttt ctactgttga catgatacaa ggcttattga tagatatgta
    41221 tagataaggt tatacaagga gaaaaatttt atgaatagca aaaaagagga tatatatgaa
    41281 ttgaattttg ggcaattaat agaagaaaaa tctggtgtta tagaagaaaa tcaaaatgtt
    41341 tttaatgcaa aagtaaaggt agctgtttct ataggaaata caacagaaac aataaaaaat
    41401 atattagatt taaaagaagg ctctataata aaattaagta agaatgtgga tgaaaaatta
    41461 gatatatatg caaacgatag attgtttgct tatggagaaa gcattattac aaatgagaag
    41521 ttatctgtaa gattatctaa aatagaagat tcagatgtaa attagcattt taaatatatc
    41581 cctttagtct attctgtatg agtttagcta aggggatatt tttataaaaa atttaaaata
    41641 tgtgtgaatt atataaatat ttttatttta tgagcgataa ctaaattata agtatgtaat
    41701 tttggaggtg aaactatgga tattaaaaat gtaagttcaa atattgtagt gaataattat
    41761 ttaaagaata catctggtat aaaaaaagtg gaagaggtta aaaaaattaa taaaacagac
    41821 aagatagagt tatctaaatt tgcaaaggaa atggcaagtg tgtcaaatat gagtgatgag
    41881 aatattagaa ataaaaaagt cgatgaaata aaaaatgcat tagaaaatgg aacttacaaa
    41941 ataaaaccaa aagaaattgc gaaaaaaatg atagaggata tgcgaggata aagtcatgat
    42001 tacagactta aaagttataa tatatgaaga aaaaaatata attagtaaga tgatggaatt
    42061 attaaaagaa caatttgatt atatagttga aaaagactta gaaaatttaa atatgttaaa
    42121 tcctaaacta gaagatatta gcagggagct tgcatccata gaaataaaga gaagacaact
    42181 ttttggtaat gatatttcaa tgagtgaagt tgttgaaaat agtaatgatg gatatttaaa
    42241 agaaatatat acagacttga aacgcattct tgctttagct aaaaatcaac aagaatcaaa
    42301 tgattctcta ataaagaaag aacttatttt tacgaaaaaa atgattaatt tcataaaacc
    42361 agctgataag caaactacaa cttataattc ttatggaaat attagaaaat aaatattagg
    42421 aggagaaata tggcaggatt attttccatt ttaaatacag ctaattcagg aatgaatgcg
    42481 caccaaaaag caatacagac aatttctcat aatataagta atctagatac agacggttat
    42541 tctaggcaaa ggaccgagtt tgctacaaat agtccaatgt atatgcctag tttgagtaat
    42601 tcaattgcaa gaggacaatt agggactgga gtacatgtaa cggatgtaac aagagctaga
    42661 aatagttttt atgattacca atttagggca gaagctcata agtatggtaa gacagtttca
    42721 aaatatgatt attacaatac tatagaaact atactaaacg aaccatcaga ctatggaata
    42781 tctgcaggta tagatgattt ttttaaagga tgggagtcat tatcaaagga tataaatagt
    42841 gacagtaaaa aaagtctagt ggtagaaaac gcatctaatt tagcaacttt aataagtgaa
    42901 agttataaga agcttgataa gttaaaagaa gatatagatt ctaatataga cactgagata
    42961 aaacaaataa atgacatgtt aaaaagtctt gaagatttaa ataaatctat tgatattata
    43021 tctggttctg gctctacacc aaatgatttg cttgatgaaa gagatagaat tttagataac
    43081 ttgagtttta aactagactt tgaaaatagt gatgttaaaa atatgcttgc agatggtaaa
    43141 ttagaactta atgaattaaa aaatccagat ggaacttgga aaacaggtat atcagggacc
    43201 ttacaaggct tgtttgaaat gcatggtaag attgatacat ataaaagcga tttaaaagat
    43261 gtatctgatg gattagctaa acagataaat gatgtttata atacgtctgc aggaataaca
    43321 gtaacagatt tttttataac ttcaaatgta gatggtgaag atattataaa gataaatcca
    43381 gctataaaga gtaacccaaa tgaattaaag cttactgctg atgaagcttc aaaaattgct
    43441 aagttaaagg atgaaaaaat agatattggg gtggctggtg gaaaagtaag tacaataagt
    43501 gaccactata aagcctttgc agaatcaatc ggtttagatt ctcaaaaagt aaatcaagat
    43561 gaagcaaatc aacgtaaaat tataaataat attgataact caagaatgag tgtttcaggt
    43621 gtatctttgg atgaagaaat gacagagctt ataaaaatac aacgttcata tcaagctagt
    43681 gcaaaagtta tgtcaacagc tgtgcaacta ctggatgttg taataaatgg aataatttaa
    43741 tagaaggggg aatttataat gagagtcagt acaggtatga tgtctagcag ctatctaaac
    43801 tcactacaag ataatctaca aagattggat aaggttaata gacaagttaa tacaacaaaa
    43861 gaaataaaca agctatcaga taatccatat aaagcaataa agatattaaa ctcaaaaagt
    43921 gaaataaaga ctatggagac ttatgttgag aattgtaaag atacagggaa ttggttagaa
    43981 actactgata ctgcattaga tcagcttgga aaattattat cagacataaa gaaaactttg
    44041 gtggcaagtg gtgatggtgc atactcagat gatgaattaa agactcttag taatgaaact
    44101 aatgaaaaaa tgaaagaaat tgcaaatgct ttaaatgcaa cacatgaagg gaagtacata
    44161 ttttcaggtt caaatacggg ggtaccacct gttgaatgta tagataatgc tgatggttca
    44221 gtgagtttaa agtttaattc tagtctaaat cttaataaat taaatgactc tttgagtatg
    44281 gatatagctc aaggaataag tgtagattat aacgttaaat tgagtagcct tggatttgac
    44341 ccaacaaaaa ctgacccatt tgaagagtta aataacatat caaaaaaatt agcaaatcca
    44401 gatgctgatg ctataaaaga gcttacaaca acttgtttgg gcgatatgga acaactaata
    44461 gaaaatacag taaatgttag gtctatatat gggacaaaag caaatacagt agaggctatg
    44521 aaggaaaaaa acgatgatag tttgatacag ttaaaggata ttttgtcaca aaatgaagaa
    44581 atagattatg gtgaaaaact tgttcaatta aaggcagcag agttaactta tcaagcttca
    44641 ctacaaacag gaggaaagtt atttaatgta tctatattag attacatata ataaaataac
    44701 gcagatatga tgaaggttac attaaaaaaa ggtatattag gttttgaaaa tttaaaagaa
    44761 tatgagcttt tagatataga agataatgat tatttaaaag aatttaattc tactgaagaa
    44821 gaaggtatag gatttgttgt tgtatctcca tttgagatta tcaatgaata tgaaatagtt
    44881 ttaaatcagg aaacaataga aaaactagaa gtgaaatctc caaaggatgt tgtattattt
    44941 aatataatta ctcttggtca gacatttgaa gaatcaactg tgaacatgaa agctcctata
    45001 gtgataaata taaaaactaa ttttggaatg caaataattt tacaggatga taaatattca
    45061 ataaggcatc cattattgag aggtgataat ggatgctagt aatttcaaga aaaaaagatg
    45121 aagcagtact tataggagaa agcatagaag taaaaattgt aggagtagat ggaaacaatg
    45181 taaaactagc tatatcagcg cctaacaata taagtatatt aagaaaagaa atatacgaaa
    45241 aagtaaagag tgagaatata aaagctacaa ataaaaatat aaaaatttta aagtcattaa
    45301 aataataagc ttggaggaag taatatatgt atggagaaaa tccttataat tcttataaac
    45361 aaaatgctgt ttttatggca tcaaaggaac aattgttact tatgcttgtt gatggagcag
    45421 taaaatatac caaaatagcc agagcagcta tcttagataa aaatacacag aaagcgcata
    45481 gagaacttgt aagagttcag gatatattta cagaactaat ggttacatta gaccaaaatg
    45541 caggacaatg ggcaaaggat atgtacaaag tttatgattt tgtaagatat gaactttcaa
    45601 gagccaatat tagaaaagac atccaggtaa tagataatgt gttacctgta atagaacaaa
    45661 ttaaagatac atggcatgaa gctgataaaa aaagtaaaga agaaagaagt aggtacaaat
    45721 aatggaatta aatttagctg aattagataa gttatcaaaa gaggaattac tattgatgct
    45781 tgtagatggc acagtaaaat ataccaatat atccaaagaa gctcttttaa ataacgacta
    45841 tttgaaagca cataatgaac ttgtaagagt tcaaaatata tttacagaac taatgactac
    45901 attagaccaa aatgcaggac aatgggcaaa ggatatgtat aaagtttatg aatttataaa
    45961 atctgaatta gcaatagctg atgaaaataa agatattaaa ataattgatg atatattgcc
    46021 aatagtaaaa caaattagag atacatggca tgaagtttac aatcaactaa aaatataatt
    46081 agatggaggg ataaaggtat gtcaagtata agtcctataa gagttacagg tctttcagga
    46141 aattttgata tggaaggcat aatcgaagct agtatgatta gagacaagga aaaagttgat
    46201 aaagcaaaac aagaacaaca aatcgttaaa tggaagcaag aaatatatag aaatgttata
    46261 caagaatcaa aagatcttta tgataaatat ctaagcataa attctcctaa tagtatagta
    46321 agtgaaaaag catactcttc tacaagaata accagttctg atgaaagtat tatagtagca
    46381 aaaggttcag ctggtgcaga aaaaataaat tatcaatttg cagtttctca aatggctgaa
    46441 ccagcaaaat ttactattaa attaaattca agtgaaccta ttgttcgaca gttccctcca
    46501 aatgccagtg gagcgagttc tttaactata ggagatgtaa atataccaat atctgaacaa
    46561 gatactacaa gtactattgt aagtaagata aactcccttt gcgcagataa tgatataaag
    46621 gcttcttata gtgagatgac aggtgaattg attatttcaa gaaaacagac tggttcgtca
    46681 tcagacatta atttaagagt aattggaaat gacaatttag ctcagcaaat tgctaatgat
    46741 aatggtatca catttataaa tgatgctggt ggaaacaaag tggcaaatgt atatggaaag
    46801 aatctagaag ctgatgtaac tgatgaacat ggaagagtaa ctcatataag taaagaacaa
    46861 aattcattta atatagataa tattgactat aatgtaaatt caaaaggaac tgcaaagttg
    46921 acttctgtca ctgatactga agaagctgtt aaaaatatgc aagcatttgt ggatgattat
    46981 aataaactga tggacaaggt ctatggttta gttactacta aaaaaccaaa agattatccg
    47041 cctcttacag atgcccaaaa agaagatatg acaactgaag aaatagaaaa atgggaaaag
    47101 aaagctaaag aaggtatact tagaaatgat gatgagttaa gaggttttgt tgaagatatt
    47161 caatctgcat tttttggaga tggaaaaaat attattgcat taagaaaact aggtatcaat
    47221 gaaagtgaaa attacaataa aaaaggtcaa atatcattta atgcagatac tttttcaaag
    47281 gctcttatag atgatagtga taaggtatac aaaacactag caggttattc ttcgaattat
    47341 gatgataagg gaatgtttga aaagctaaaa gatattgtat atgaatattc tggaagttca
    47401 acttctaaac ttcctaaaaa agcaggtata gaaaaaactg cttctgctag tgaaaatgta
    47461 tattcaaaac aaattgcaga gcaagaaaga aatataagca ggttagttga aaaaatgaat
    47521 gataaagaga aaagacttta tgctaaatat tcagccttag aatctttgtt gaatcagtat
    47581 tcttcccaaa tgaattattt ctcacaagca cagggtaatt aattatggat aaattaaaag
    47641 aaaaattaaa tttatataaa gatatatctt tacaaattat aaatttgatt gaaaaggaag
    47701 aatatataaa gataagtatt aagttaggtg aaagacaaga gattataaat agtgtaagtg
    47761 aaattgatag aaatgatttt atacagcttt ataatagaat ggaattaatt gaaattgata
    47821 gcaggataag agatatttta caaggacaat tattagaagt aaaaaaagaa ttacatgagt
    47881 ataagcttac taaacaagtg aacacaatgt attataactt aaatagagaa aaagtaaata
    47941 tttttaataa aaaagtataa agttatgtac catcttgtcc gattatataa atgaagaatt
    48001 aataaaaaag attaaaagta gaaatgacaa ggatgtcaac tatactaagg agggtaaaat
    48061 aatgagagtt aatacaaatg taagtgcttt gatagcaaat aaccaaatgg gaagaaacgt
    48121 aaatgcacaa agtaagtcta tggagaagct atcttctggt gttagaatta agagagctgc
    48181 tgacgatgct gctgggcttg ctatatctga gaaaatgaga gctcaaataa aaggtttaga
    48241 ccaagcagga agaaacgttc aagatggtat atctgttgta caaacagcag aaggtgcatt
    48301 agaagaaact ggtaacatac tacaaagaat gagaacttta tcagtacaat cttcaaatga
    48361 aactaatact gctgaagaaa gacaaaagat agctgatgag ttactacaat taaaagatga
    48421 agttgaaaga atatcaagct caattgagtt taatggtaag aaattacttg atggaagttc
    48481 tacagaaata agattacaag ttggagcaaa ctttggaaca aatgttgcag gaacatctaa
    48541 caacaacaat gaaataaaag ttgctctagt aaatacttca agtataatga gtaaagcagg
    48601 tataacaagt tctacaatag caagcttaaa tgcagatgga acttctggaa caaatgcagc
    48661 taaacaaatg gtatctagct tagatgtagc tcttaaagaa ttaaatacat caagagcaaa
    48721 attaggggca caacaaaata gactagaatc aactcaaaac aacttaaata atactataga
    48781 aaatgttaca gcagctgaat caagaataag agatacagat gttgcttcag aaatggttaa
    48841 cttatctaaa atgaatatat tagttcaagc atcacagtca atgcttgctc aagctaatca
    48901 acaaccacaa ggagttttac aattattagg ataaaataat tttgtatatt ggatatagaa
    48961 gaaagggtaa ggctttgctt tactcctttc tttttttaca aatatacttt tgaaaggaaa
    49021 atttatatgt tacttagtat agttatgatt gttaaaaatg aagaaaaaat acttgaaaaa
    49081 actttaaaat cattaaccac attaagaaat tctatagaaa gtgaacttat aatagtcgat
    49141 acaggttcta cagatgatac tataaaaata tctaagaagt acacggaaaa agtgtatttt
    49201 cataattgga ataatgattt ttctagtatg agaaatatat caatatccta tgctaaaggt
    49261 gaatggttac ttatattaga tgcagatgaa atactaattg attcttcaac tattgtaaaa
    49321 ttttttaaag atggtcttga taaaaaattt aattctgctt caatacaatt aaaaaatctt
    49381 tactcatatg ataaaaaatt atatggatat tgttcagtgc ttagactttt taaaaacgtt
    49441 gattttagat accatggtaa agtacatgaa caaccaatat acaaaaaccc tatatttaat
    49501 aatgttgctg attttgaaca ttatggatat ttgtttgaag atgaagaaat aagattaaat
    49561 aaggtgaaaa gaaatgaaaa actattattt caagagttaa aagagaatga taattctcca
    49621 tatacaaact atcaattagg gaaaaatttt attatattag gaaaatatca ggaggcttta
    49681 tactatcttg agaaatctta tgaattatat tctaaactag aattggcacc tggttacttg
    49741 ataacaagcc ttgtaaaaac atatttatat ttaggaaaac ataagaagtg tgaaagattg
    49801 tgcttaaagt atattaagaa agacatgaat aatattgata tatattatta tattgcacaa
    49861 gcacaagtag atttaggaaa gtatgaaaat agtatagatt cgtataagag atatatttac
    49921 ttgttagata attatgaaat aagtacacaa gcaaatagtt tattttcaga cactgatact
    49981 gtagggctta gagatgaggc tattattaca ctgataaaga tttattataa gcttgaaaaa
    50041 tatgagtttg taatttcaga gtataataac attgaagatg tggaaaagaa aaagaatgtg
    50101 tactttagct tatttatgtc actatataaa ttgaatagat ttgaagatat aaaaaattat
    50161 tataaagaag tttcaaattc taaaattgaa aaaaatagtt tttatagaaa tatagaagaa
    50221 gttataaata atattaaaga ggatgaaaaa gagtatgtat ataaaatcct ttgtgacatt
    50281 gaaggtaatt atggcatttt aaatcaaata aggataaata aatgtgtatc tatagataaa
    50341 tgtaaagaaa tactcaatga agaaaaggaa ataatttatg catatattat aaaaatagct
    50401 tttgaagaga agattgattt actagatatt ttttatgaaa tggaatatgt atggatagag
    50461 aaatatctaa aatatctttt agcattagaa agaagtttta atttagtact atataagtac
    50521 ataattagtc gtccaaatac atcagatatg gaaaagataa gagtatataa agctatatct
    50581 aaagtagttt tagaaagtat aagcttaagt gatgaaaaat ataaggagat tttttatctt
    50641 tatataatgt attcttataa gtacataaga tacatatata gcaatttaag tgattttgaa
    50701 ttaataaaat ttgtttgtaa tgatttagat aagttcacta tagaatttaa gcatctactt
    50761 gatattaaaa ataaagtaaa taatgctaat gaaaaattag agtatataca tagtatgagg
    50821 aaattactaa atgagtatcc tttttataat aaaataataa aaatacttat aggtgaatta
    50881 gaagaaaata taaaagaaag tgaagaattt aaggatttaa aagatagttt tattattagt
    50941 atagaaaata tgattgaaac tggcaaaata aatgatgcga aattattggt agatgactat
    51001 tcaaaaacat ttgtggatga tataaagatt ttaaatataa agggaatttt atacatgttt
    51061 gaaaataagc ttgataaagc tgattttatg ttaaaaaagg cattatcatt agatgtagaa
    51121 aatgaagata ctatatataa tatagaatac ttaaaaagtt taagataagt caaaaatagg
    51181 agaattgaag aatgaatata ccaatagtgg ttaatgaaaa atctaaagac ataataaaag
    51241 attggcaata tacatgtaca aatgaagata taaaatttac aagcataata atattgacat
    51301 ataatcaaat agaatatact aaattatgta ttgaaagtat taggaaattt accccaaaga
    51361 ataaatatga aataataata attgataata actcttctga tggaacagtt gagtggttaa
    51421 agggacaatc tgatataaaa tctgtgtata ataacaaaaa cttaggattt ccaaaaggat
    51481 gcaatcaagg tattgagtta gctactggtg aaaacatatt gttgttaaat aatgatgtaa
    51541 tagttactcc aaattggctc tataatttga ataaagcttt atggtctcaa gataatatag
    51601 gtgctgtagg acctattacg aatgcatgtt catattatca gcaaattgat gttgattata
    51661 agtcaattga ggacatgttt atatttgcac acaaaataaa taaatctaat attaacctat
    51721 ggaaatatag attgaagtta gttggatttt gcatgttaat aaaaaaaact gttctggata
    51781 atgtaggggt tttagatgaa ttattcacac ctggaaattt tgaagatgat gatttatctt
    51841 ttaggatgat agagtcagga tataagttat tattatgcca ggatactttt atacaccatt
    51901 ttggaagtgt gtcttttaaa gaaaatcgta ataaatatac agatataatg tatattaata
    51961 gaagaaaatt tgaaactaag tggggattta atccagaata tagtggaatg ataagaacag
    52021 atttgatttc taaaatagat gatagtttgg aggcaaatat taatgtttta gaaataggat
    52081 gcggtatagg ggctactctt ttagaaataa aaaatatata taaaaatgca tcaatatatg
    52141 gaatagaaat tagtgagtca gcaggtaaac ttgcaaagta tagtgcagat gtacttatag
    52201 caaatataga aaaagtaaaa ttggattata aaaaagattt ttttgattat ataatattgg
    52261 gagatgtact tgaacatttg attgacccat ggaagatagt caatgaattg aaacaatatc
    52321 taaagaagga tggttatctg gtatctagta taccaaatat tatgcatgtt tctgttttaa
    52381 gaaatcttgt gttaggtaat tttacatatg aagattcagg aattttggac aagactcatt
    52441 taaggttttt tacattaaat gagataacaa aaatgtttaa tgatagtaat tacataatta
    52501 atagtattac agctactagt atgccacttt cggaaattga taatagcttc attgatacaa
    52561 tatgtaagga aagctgtaaa gaaatgagac aacagtacga atcttatcaa tatatagtaa
    52621 aagcctctaa aatcctagat actaaaagat attctagtat tagtatgatt aatttaaaat
    52681 acgctttaat gagaattgat aatgaattag atgtagatag taatttaagt tatatatttg
    52741 ataattataa tataactgaa ccatgttttg ttgatgatat tgaatatcta attgatacat
    52801 ttgtgataaa taaagcaact ctattaaata gattaggagt tgaggcattt aacagaggtc
    52861 taggagattt tagtataaac atgtttatga cagtattaga gatggataga gatgatattg
    52921 actcaatata taatataaca agtgtattat gtgaattaga agaatttgat actgcttata
    52981 atttaattaa aaatagtagc gaaaaagtac agagtgaaag tgatatacaa gagatacttt
    53041 gttttattga ggggaagaaa tatgaataat gataagatat gttttataac ctgtgtaaat
    53101 gatgaaaggc tttatgaaga atgtcttgta tatataaata gcctagacat tcctaaaaac
    53161 tttagtatag aaacagtagc tttaagagga gccgattcta ttgcctctgc ttataataaa
    53221 gctatgagag aaacagattc taagtataag gtatacttac atcaagatac ttttataatt
    53281 aataaaaatt tcatacatga tattttagag atatttaaaa aaaatacaga tgtcggaatg
    53341 attggtgtag ctggagtaaa agatatgcct gtgaatggaa tttggtggga ttctgataaa
    53401 aaagcaggga aagtatatga tagtcataca ggtaaaatgg atatttatga atttagtaac
    53461 tttgaagaat gttttaatga agttatggct atagatggat taattatgat tactcaatat
    53521 gatgtatttt ggagagagga taagtttgat gggtggcatt tttatgattt gtcacagagt
    53581 atggagttta gacaaaataa atacaaagtt attgtaccaa aacaaaataa gccttggtgt
    53641 atgcatgatt ctggagtagt aaatataaat aatggatatg atgaatatag gataaaattt
    53701 gtaaaagagt acataaatct tgatttatat agagaaaatt tttatgaatt tgataagaag
    53761 aaagcaagta ccatacttaa gagtaataag catgtaatgg attgtatgaa agaggagctt
    53821 acagaacaat taagattaaa gaattacaag gatgttttag gtattgtttc taaaattgct
    53881 catttttctg tttttaatca tactggtttg tattcttgtg aagaatgtga gagagcattg
    53941 ctagaatgtg caaataattt accagaaata gaaaatacga aattatttac aaaaaaagat
    54001 ttaaaaagaa gaaaagtatt acatgtttta agtgaaggat attcaacagg aggtcataca
    54061 agactagtta aaaattggat tgaaattgac aaagactctg ttcattcagt tgtaactaca
    54121 tggcaatcag atacactgcc agactggtta ttaaaagcaa taaatgatag tggtggcgaa
    54181 gttatatctt tggatttaat ttcagatgat tatttaaaaa gagctgtagc tttgaggaaa
    54241 atagcttatg actgggctga tatagttatt ttatatgttc atatgtggga tacaatacct
    54301 gttgttgctt ttggagttga tgggaaaata cctattttac atgttaatca ctatgatagt
    54361 actttttggt tagggacaag tattgcagat attgtcattg attttagcga agctagtcaa
    54421 ttaattacat tagataaaag aggcatagat aaatctgaaa tattaccaat gccattaaaa
    54481 gaaaaagaag tattttcaaa atctgaagtt agaaaacgat ataatttaga ggatgatgtg
    54541 acaataatat tgactattgc tagtgaaaga aaatacaata gtgtaaatga tattaattac
    54601 tttaaaattg ctaaaacatt gattgaaaat acagataata caattattat tgttgtagga
    54661 gttgatacag agaatctcta ttggaaaact ttaagtaacg ttacagataa tagagttata
    54721 tgttttggaa caacagcaaa tatagacgat ttttacaaga tttcggatat atatatggag
    54781 tctttcatgg taggaagtca tacttcaaaa ctagatgcaa ttttatatga tttaattcct
    54841 gttaagttta aaaatgaagt ttcaccaatt tttacaaata tgtggaattt tatagataag
    54901 tttgattata agaatataaa agaggttata gatatgataa aaaggtacaa tactagtgaa
    54961 tttgacaggg ataggataaa agaaaaacaa tcggaaataa aacattttgt tatagataaa
    55021 cactgtattg aaataaaaaa ctatatagac aaaatatata atgaagctaa tcatcataaa
    55081 gttaagtatg atttatataa aaatgatgaa atcgaggact atcagctttt tgtagcatta
    55141 tatggctata tggtaaaaaa taaaaacatg tcataggtgg taaaatgaac aatattcata
    55201 tcaataaatt tgaaaaaagc tgtgaaagaa actgggatta ttttgtagaa aataaatcta
    55261 taaatggtac atttctgcaa actagaaatt tccttaatta tcatgaggag ggaaaattca
    55321 ctgaccactc attaataata tgtaaaggtg aagaaatact agcagtcgta cctgcatgtg
    55381 aaacttatga agatggtgaa agaatatttt tttctcattt agggagtact tttggtggta
    55441 ttataataag aagtggtttt aatgatatta ggcatgtaaa tgccattaca aataagttag
    55501 aaatatattt acgggaacaa aatttcgata aagtatattt aaaaaataca tcaagaatat
    55561 tttgtaaaga ggatacttca ttactagaat attttttatt taagaataat tacatgtttt
    55621 atgatgaatt aagtatgttt ttagaattaa gtaagtataa agaagatata ttagccaatt
    55681 ttaaatacag taaaagaaga gattttaaat attctttgaa gaataatctt acctttaaaa
    55741 gactgtatag tgatgaagat atagtttgtt tttttaattt actttctaat tgtttagata
    55801 gtaaaggagc taaagtaata cattcagtag aagaactttt ggagtttaaa aataatagat
    55861 taaaagatat tgtagaattt tatgcagtat atattgatga cattatgatt tgtgggagca
    55921 tggtatttaa ctttcaagaa agagtttatc atactcaata tctagcatca aattcgacat
    55981 ataataaata ttatccaatg atatttttat actataatct aataaaagat gctttagaga
    56041 gaaattttaa gtatctttct tttggaatta gcactctaaa tagaggcaaa tacttagacg
    56101 agggtttagc tacatttaaa gaaggttttg gttcaagtgc aatttgtaac agaacatact
    56161 ataaaaatat aaataagtga gaatcatgtt ttatagagtt tttagaatat agtaaatatc
    56221 tagtactcta acattacata aaaataatta gtttataaag aaggtttgta tatgaaaaga
    56281 ttaatgattt taggctcaat taagtatttt gagaatattg ttatatcagc taaaaaagag
    56341 ggaatatata cgattgtttg tgataataga attgatactc ctgcgaaaaa gatttgtgat
    56401 gaagcaatag atgttgatgt atttgatttt gataaaataa aaagtatagc tatagataaa
    56461 aagatagatg gaattttaac tggatttaca gattctttaa tgaaaccata tgtttatatt
    56521 gcaaatgaac taaatttacc atgtgtgatt tcttgcaatc aacttgaatc tgtaactaac
    56581 aaggctatta tgaaaaaata ttttaaaaat aatgcaatac ctacaactga ttactgtatt
    56641 attgaaagtc taaaagattt agaaaaaata caaggattaa attttccact tgtaataaaa
    56701 cctgttgatg gttatggttc aagaggtgta tattttgtat caaatataga agaattaata
    56761 gaaaaatttg aatattctaa ggaagcctca caagatggac aagtaataat tgaggaattt
    56821 tatgaaagtg aggaaataca aggactagct tgggttcata atggagagtc acatgtattt
    56881 tatattggag atagagagct tgtaaacata catacaggaa gagctggaaa accagataga
    56941 ttactttatc catcaaagta ttgttttcaa tatgaggagg aaataaaatc tatatatcaa
    57001 aatataacac aggcttttga tataaaaaat ggacctcttt atgtacaaat gttagtggga
    57061 gcatatggaa taaaggtatc tgaagtaatg ccaagattac ctggaggttg tgactatatg
    57121 gctatttctc aaataacaga tttagacata ggaagtttat ttgcaaactt tagtgtgaat
    57181 aatgaagtaa attttgatga aataaagaaa tataatatgc atctatcaaa atgtgtatat
    57241 gcattaccaa tatacataag acccgggaca ataaaaaaga taaataatat agataaaata
    57301 gaaaacttag attatgtcac tcaatttcta ttactagtaa aagaaggaga tacaatagaa
    57361 ttatatgaag atgagagaca ggattgtgga agagtttatg gaatagcaaa taatatattt
    57421 gatgcaaata taaaaaagaa atgtattcat gaaatgatag aaatacttga tgaaaataat
    57481 gaaaatatga tagaaaattt ttaaataagg gagtatgata gatatgaagc taataactca
    57541 tgaacaaatt atgtcattaa acatttctca gaaacaagga tatgagtgga taaaagaatc
    57601 tttcttaaca aaaaaagatt gtcaattacc accaaaaata agcatggtag aagaaggaca
    57661 tgtattttac aatgtaatgc catccctaaa tcataatcat atgattggtg gaataaaaat
    57721 ggttacaaga ttgccaggga gaaatccaag tttaaactca gagatatttc tatacaatat
    57781 ggaagatgct aaattaaagg ctattttgga tggtaattat attacagctt ttaggactgc
    57841 tgctgttgct gccttggcta tcgatacatt tgctaaaaaa gattttaata ctattgctat
    57901 tatgggttta ggtgtaactg cttctgctat aatgaatatg ctttcatata ctcttaaaga
    57961 taaaaatata aatataaagt tacttaaata taaagaccaa gcagagttgt ttgtaaaaaa
    58021 gtatgaaaaa aatgaacaat ttagttttga aatatgtgat acacatgaag aacttattgt
    58081 agattcagat gtagttattt ctactgtgac atatacagat gaatatttat cagaatttaa
    58141 atggtttaaa aaaggtgctt tattattacc tgtacatgtt atgggatttg gaaatgttga
    58201 ttatctattt gataaagtat atttagatga ttataatcat ttgaaacatc tagaaaatat
    58261 agatagatat aaatattctt gtgaatttta tgatgtttta agtaaacaag ctaaaggaag
    58321 agaaaatgat gatgagagaa taatatctta caatataggt ttgtcaatac atgatatatt
    58381 atttgcaaat aaaatttacg aattgtgtga aacactaagc tgtgaagaaa tagaattaaa
    58441 agaaccaaaa gaaaaatatt ggatatagtt tatttcattc atatttacaa tagtttattg
    58501 taaatatgaa tatgaagtaa tatattgtta gaaaattagc atgaatagga tagataaatt
    58561 tatggataaa tataatttaa ttaggttcgt atctattgga aacgaatata taggaaattt
    58621 agttgcatta gaatcaaata aagtaatacc ttttgatata aagagagttt attacatata
    58681 tgatgtacca aacaatgtaa agagaggatt tcatgcacac aaaaacttgg aacaagtact
    58741 agtttgccta aatggaagtg tgaagataaa atgttatgat ggtgtaaaag agactatatt
    58801 taatttacat aaaaatgatg ttggattata tataggaacg ggagtgtggc atgagatgtt
    58861 tgattttgat gaaaaaactg ttttaatttc tatagcatct gaacattata atgaagaaga
    58921 ttatattaga gactataaag aatttttaaa gtatttaaat aatgtgtagt tattatacaa
    58981 ttagtgatgt attttcttaa ttaaataaat ttaagatagc cacatagaga atagatagat
    59041 taggatgtga atttattgtt ggttaaattt aataatttat taaaacagtt ccaaactcat
    59101 aaagaagaat atgaacagaa gattaaggat gtaatggaaa gtggatatta tatccttgga
    59161 aatgaagtaa agcattttga agaagaattt gctaactatg taggtagcaa atattgtgtt
    59221 ggtttagcca gtggtttaga tgcactgata attgctttta gagcattagg aataagcaaa
    59281 ggtgatgaag taatcgtgca atcaaataca tatattgcta gtgttatggg aatcagtata
    59341 aatggagcaa caccagtatt tgtagaacca aatgaatatt ataatataga ttcatctaag
    59401 atagaagaaa agataaatag caaaacaaaa gctatattag tagtgcattt atatggtcaa
    59461 gcaagtaata tgaaagatat acaagaatta tgtgataagt ataacttgta tttaattgaa
    59521 gattgtgctc aatctcatgg agctaaatat gatggaaaaa tgacaggaac atttggtgat
    59581 ataggttgtt ttagttttta tccaagtaaa aatttgggtg catttggaga tgcaggagct
    59641 atagtaacta gtaatgagga aatagctgat aaagtgaaaa ttcttagaaa ctatggctca
    59701 gaaaagcgat attataataa atttgtcgga tataattcaa gattggacga aattcaggca
    59761 ggtttattaa gagtaaaact taaatatcta aatgaaattg aaattgaaaa atcaaaaatc
    59821 gtagatagat atcttaatga aattaataat cccaaagtca tacttccaaa gatagaaaat
    59881 aattgtactc atgtatggca tttatttgtt ttacaagttg aaaaacgaga tacatttatg
    59941 gaatacttaa agaaaagtgg tatagagtct ataatacatt atccgatacc accacatcta
    60001 tctgaagcat atgcttattt gggatataaa aaggggagtt ttaatatagc tgagaactat
    60061 tcagataaag ttgttagtat acctttattt attggtatgg aagatgaaga agttagttat
    60121 ataattaaaa ttataaatga atattaaact actcataata atatcaaaaa taaatttttt
    60181 atatatcatt tatttaaatt tcgttaattg acatttttaa atattgatat attgtacaaa
    60241 taaaattgaa atatatggaa aaatatagaa ttaagatgag atttgtctta tatttttata
    60301 aattaaaaat attttcaaag agtttattat aaaattgtaa actatagtgt ttataatctt
    60361 tgtaattatt ggtaattaaa tttaaaaaat aaaatattta attatacaca aaaaagatat
    60421 ttaaaaaatt tgttatttat tgtatactta agttaaaact aaataggcaa atctagagaa
    60481 atctagtgac gcaaagctat agggactaag gtttatatac ataaactatg tcagccagtt
    60541 gccaaaaaga gtcctaggtg tattgtatac ctaagaaaag tctataatga ctgccttttt
    60601 ggcagtcatt ttgttatgga aaaatcactt tatttcagta gaaaatacac ataataacat
    60661 attttaccaa ttataacata aaataaagaa aaattatctc aaaaagttac tattttacaa
    60721 aaaatgactt ctttatttat ttaaattaat cgcatttcca ttacattaat acaataatgt
    60781 atcaatttag taagaaaact aatatttttt taatgaagtc ccatgaaaat ataaaaaaat
    60841 tttaatatgt atttaaatat ttcttcgaaa agttgctctt ttttgtaaat atagcaactt
    60901 catttttttt attaataaac aaaatagata aaatatattt tgaggagggg tgagtgtgaa
    60961 tacatatgac attataaaaa tgggattaga tgcaactaat ctaagaagtc agacaatagc
    61021 aaataatata gcaaatataa atactgaagg atataaaaga cattatataa cttttgaaga
    61081 aacactaaat gatgctatgc ctaaaataga agaaaaaaca gacaattcta aaggtttaag
    61141 agtagatggt aataatgtag acatagaaga agaaaaagta aatcaagcaa tggcaacatt
    61201 acaatataat gctttgataa gttttgcaaa tggaaaaata gcaatgacca aatcaataat
    61261 aagtgggagg taattagaag atgagtgtgt tcagtggaat gagaatatct gctagtggat
    61321 taacagcaga aagtttgaaa atggatatca tatcatccaa tgtagctaat ataaatgcta
    61381 caagaggtcc aaatggagaa gcatatagga gaaaagttgt ttcatttgaa gaaaactatg
    61441 ataataaatt aggtatgcta ggagtaaaag ttacatctgt tgaagatgat aaatcacctc
    61501 ttaaagaagt atatgaccca tctcatccag atgcaaagcc aaatggatat gtagaatatc
    61561 caaatgtaaa tatattggta gaaatgacag atttaataac agcttcacga gcatatgatt
    61621 ctaacgtaga tacattgaat gctcagaagt ctatgatatc aaaagctttg gaaataggaa
    61681 agtagggata aattatgcca attacacaaa ttaacaattt aatgcaaggt gcaaagttag
    61741 ataatttgat tggagaagca aagccattaa ctcttaataa taaagaagaa aaaaagaatt
    61801 ttgaagatgt aataatagat actatagata aagttaattt tcaacaagta acagcagatg
    61861 atatgaaaga aaaatttata aaaggcgaag atgtttctat gcatgaagtt atgttaatag
    61921 gtcaagaagc acaactatct atgcaatatt taatagaagt tagaaataag attcatgatg
    61981 catatcaaga aatgaataag gtgcaaattt agccttttga acaggagtaa taatcaatga
    62041 taaccagttt taaaaataag attaaggagc aagttgctaa atctaggaca aagataagtt
    62101 ctttaaaaaa gggaactaaa atagcattag gtataggggt tattgctata tgtttagcgc
    62161 tagtatttac agcaatatct gcgagcaaaa ataagtatgc agtcttattt tcagaactag
    62221 atgctcaaga tgctgcagat atatcagcag agctagagtc taaaaagata gatactaagg
    62281 taaaaggaag tacgatttat gtacctagaa cagaagttga taagttaagg ctggagttag
    62341 cgccaagtct tacaggtggt tctaaaggat ttgcactaat ggatgatagt tcatcaatag
    62401 ggcttactga tgaagaattt cagattaaga aacaaagaat gatacaaggt gaaatagaaa
    62461 aaacaataaa gagttttcca caagtggaag acactagagt acatataaca tttggagagt
    62521 catcagtatt tgagaaggag gctgttccag ggagtgcagc agtttatttg atgctaaaac
    62581 cagggacgac tttagaaaaa aaccaaataa agtctgttat ggcacttata tcaggaagcg
    62641 ttacaaatat accagagaaa aatgttcagg ttattgataa caaaatgaat ttattatctg
    62701 aaggtatttt ggaggatgaa aatgttgatg aaaataatca accaataaat agtggcatta
    62761 gtgttgataa aaataaggca tctgaacaag cattgaataa acaactagaa aagtctattt
    62821 tagaaatgct agaaccgata tttggtaagg gaaaggtgaa agctacagta aatgctgatt
    62881 taagttttga tacagctgaa aaaactgaga taaaaattga ccctgataaa gttgcaataa
    62941 aggagacaag gtcgaaaaat tcatctaaat ctgctgcaaa taatgttcaa ggtgtagatg
    63001 ctaacatgaa taaccaagga aataacaatg gtactaatac agaagatagt ttagatgaga
    63061 gttttgagta tgaaacaggt aagattgaaa ctcacactat agttgcgcct ggagaactta
    63121 atagattgac agcttctgtt gcaatagatg gaaaaatagc taaaggtgtt caagctgatg
    63181 tagaggatat tgttaataat gctataggta tggatggagc gaggggagat actcttagcg
    63241 ttgtttcaat ggtatttgac ccagaaggta agaaagaggc taaacaagag ctggaagaga
    63301 ttaaaaaaga aggatttaaa aagaacataa taaaagcagt tattggagta gtagcagtaa
    63361 tagcagttgg agctattgga tacttaatat ataagaaaag aagtgaacga gaagatatgg
    63421 attatgaaga tgaagattat atttctaaat ctgattctgt tgataggaag gataatcctc
    63481 tattaggaga tgacccagaa ctgacattag aggaagctgt taaaatgtat gcagaagaaa
    63541 agccagacca agtaacagag ataataaaga cttggttaaa tgagtaaggg ggatagaaag
    63601 tgtccacgga aattacaaat gttaatgcgt ttgacttaag tgatataaat gaaagtgata
    63661 agaatgagaa ggtagaaggt gagggtttaa aaaaagctgc tgtattatta atgacattag
    63721 gcccaaatgt gtctagtgat ataataaaaa gcttgcctga taaacaagtt caaaaaatag
    63781 gtttggaaat tgcaaatatt tcttcaatag cttcaaaaga aagaagagaa atcttaaaag
    63841 agtttgtaga aataaatagg gcaaaagatt atgttataga aggtgggctt gaatatgcaa
    63901 gagagttatt aagtaatgct ttaggaaatg ttaaagcaaa caaattactt gaaggtatat
    63961 caataaatac aagtacaaag ccttttaaac atattataaa actagatgta aagaagatat
    64021 tagaaatact taggaatgaa agtgcacaaa ctatagccgt tttacttgca catatggaac
    64081 cagaaaatgg agcagaagtt ttatcatact tagattttga tttacaaaat gaagtagcta
    64141 tgagaataag ctcaatgggt tcaatatctc cagaagtaat aaaggtaatt gaaagttcat
    64201 tagaagataa attacattca ataagtggtg atgattttaa tgattatgga ggggtgtcta
    64261 ccttagttca aatattgatt aattctgata gaaaaacaga aaagaatatt ttgggaacta
    64321 ttgaagaaca aaacccggat ttagcagctc aaattaaatc tcatatattt gtctttgaag
    64381 atattgtcaa gttagatgat ataagcatac aaaaagtgtt aaaagaagtg actatgaaag
    64441 atttagtata tgccttaaaa ggtgtagatg atgagatttc agatgctata tatagaaatc
    64501 aatcttctag agcagcagat gcacttaaag aagaaatgga aatggttggt gttataaagg
    64561 ttacacaagt tgaggcttct caacaaaaga tagctaatat cgtaagaaaa cttgaaagag
    64621 aaggtgccat aactattgta aggaattttg gtggtgactt tgttgaataa taagattatt
    64681 aaaagtaaaa aagcattata taaaggagtg ctagatttaa ccataataga taaagttaga
    64741 gtgggagaat caaatgtaaa taaagaaaat gattgtagat ttagggatga ggtaataaaa
    64801 gaagctatag aatctgctga gataagaaag aatgagatat tagaagaagc aaaaatgaat
    64861 gcacaaaata tagaaaagca agcatatgaa aaagggtata gtcaaggtca aaaaaatgga
    64921 tatgaagatg gatataaaga gtcatatgat gaatataccc aaaaagctaa agatgaagca
    64981 gattttataa aaaatcaggc agacttaata ctattacaag ctaatgagaa gatgactgag
    65041 tacataaaag aaaaaaataa agagattgta agacttgcta ttaatatggc tagttctgtt
    65101 ctaaaaaagc atttcgaaga tgaagaatct atgagtgatt tgttaaagca aattattcaa
    65161 gattatgaag gaagtagttc atttatagta agatgtaatt ctttctataa agataatata
    65221 gagaaagagt ttgaattatt caaagaggaa acatcactaa aatcaagtgt atttgttatt
    65281 gcagatgata gtatagataa aggcaatgct attatccaaa aggaaaatgg aagaataata
    65341 gttggtattg attgtgctat ggaaaaacta aaagaagaat tgcttggtga ataaagtatg
    65401 tataaaactg atatatctat agattttgac aaaataaata agaaaataga aaatttagaa
    65461 ctcactatat cagaaggtag agtaaagaag ataataggac ttactgtaga agttgaagga
    65521 ataaaagctt ttgttgggga gttatgcgtt atatacaacc aagttaataa accagtgaat
    65581 tgtgaagtag taggttttaa agataaagaa gtcatattaa tggcgttggg agaattaaca
    65641 ttgatagcac ctggttgtaa agttatttct aaggggatac ctttaagtgt tatgtgtagt
    65701 gataatttac taggtaaagt acttgatggt cttggaaatc ctatagacaa ctcagatgct
    65761 gttttaggag atagatacaa cctgaacaat gaacctcctg acccaatgaa gagaaaaaag
    65821 atacgaaata taatggaaac aggtgtaaga gcaatagatg catttactac ttgtggtgaa
    65881 ggacagagaa tcggcatatt tgcaggaagt ggagtaggta agagtacgac tctaggtatg
    65941 attgctagga atgcaaaagc agatgtaaat gtaattgctc ttattggaga aagaggaaga
    66001 gaagtactag attttattga taaagattta ggtgaagagg gaatgaaaaa atctgttgtt
    66061 gtgtgtgcaa catcagataa agcccctcta gttaggttaa aaggtgctct tactgctact
    66121 gcaatagcag aatattttag agaccaaggc aaaaaagtaa tacttatgat ggattcagta
    66181 actagatttg ctatggcaca aagagaagtt ggtgtagcaa taggagagcc accagctcaa
    66241 aaaggatata caccatctgt atttgcaatg ttgccaaaac ttatggagag aacagggaca
    66301 tcagataaag gttctataac tgcattttat acagtattag ttgatggaga tgactttaat
    66361 gagccaatag cagatacaac aagagggata cttgatggtc atatagtttt atctagagac
    66421 ttggcaaata agaatcacta tccttctata gatgtattaa acagtttaag taggcttatg
    66481 aatgaaattg cttcaaaaga agacataaaa atagcgtctt ttgcaagaga catgcttgct
    66541 gagtatagag aagcagaaga tttgataaat ataggtgcat atgcttcagg tacaaacaaa
    66601 aaaatagatg aagcaatcta ttatcatgag catattatta attttttaaa acaaggaata
    66661 aatgaaaaga gttcttttaa tgaaactata agtagtttaa gaagaatctt tgaataaaca
    66721 atttaaaaaa atatttgaat aggttgtgat ggaattggat aaaaatttta agtttagatt
    66781 acagaaagtt ttagacttaa aaataaaaga tgaagaagag ataaaaatgg aatttgctaa
    66841 gattcaacaa aaaaaaatag atatagaaac taatttagaa aacttagaaa gtaattacag
    66901 caaatattct ataagtaaaa ataatgataa tgttcaaaat caaaaaataa ctattaacta
    66961 tttgctagct ttaaacaact ctataatgga tttatcagaa gaactggata agtcgacaaa
    67021 tgaacttgaa aaagctagaa aacagcttat aagcaaacag atagagagaa agtcattaga
    67081 aaaattaaaa gaaaaaaaat atggacagta ttataaagaa gaacagttaa aagaacaaag
    67141 cactaatgat gagtttgcaa gcatgagtta tttgagaaat agacaagttc tataaaataa
    67201 taggaagtga ggatattatt gtatgaagat acaagcagat tcttataata ttattaaaga
    67261 tattgggaat agaaaaaact catctaagaa taaaaatata aaaaataata aatttgaaga
    67321 taatctatat aagacaacag accataaaaa tgttaaagat agaagagaaa caagtaagca
    67381 aaatgttagt tcagatagac cgggaaatag tgataatgag tgtcatttag atgaagataa
    67441 aagtaatcac ttagaagatg aaaatacata tgaaaaagat tgtagtaaga ataatgaagc
    67501 tttacagcaa ttactgaatc ttttaaaaga gaattataaa aaagataaag atataaacac
    67561 tatattgaat aatataaaaa aactaagtat atcagatgaa ttaaaacaag aacttaagct
    67621 taataaaaat atattgaata aaattgcaaa tcaaaattta gagttaaatg gagctaatac
    67681 aaataaccct aatgatatag aaaatttaga cataatgaag ttaagagaac ttttagaaaa
    67741 taatgctagt gaagatattc aagtaattag taaaactaca gaaaatgata ctaaaagcat
    67801 agacttatac agttttgata gtaatagaat ggatactctt aactcaaata aacagaaaga
    67861 tgatagttct gatattttgg aaaaactagc agggttaaat ggaaataaga gtggaaattt
    67921 tggacaagta ataaataaaa gcgttgatat gaataaaatt aaaaatgata atgttaattt
    67981 aaaacagata gaatctaatg taatggatga ttctataaaa gctattaagc atatgaaaac
    68041 aaatgatata caagaattga caattaaatt aagaccaaaa gaattaggag atatgaacat
    68101 acaattatta aaagatggtg aaagtatgag agctgttgtg actgttttca ataaagatgt
    68161 ctttgactct ataaataaaa acatagcaga tttaaagcaa catcttgaac ttacaaatgt
    68221 aaatataaaa gatgtatcag tgcaaatgca tagcgataat acaaatacat ctgatacctt
    68281 tgataaagca tttgaacaac agaatagaca aaataaccaa gaaaacatga gtaatcaaaa
    68341 tacaaatgat aagcgtaaca atgtagtcat agaagatgag attaaagaaa atattattga
    68401 tgatgataga gtagatttac tagcttagta agggggaagt attgcatgta cggaatagca
    68461 acggctttgg caggaactca ggtaaactat aggtcaaata acttaagcca acttgaaaga
    68521 aatattaatg atattgccaa caaacaagtt agaagtaaag gaaatcagac agtaacagac
    68581 aatgggactc caattatagg acaaggtgat gatgctgata aagacttgtt tatgaagatt
    68641 cttgtagcac agatgggtaa tcaagaccca atgaatccac aagacccaac ggagtatgta
    68701 tcacaattag cacagtttgc aactttagaa aaaatgtcag ctatgaatga taagctagat
    68761 atacttttag ccttaagtaa ctctactcta ataaactctg ctttgagtat ggcaacatca
    68821 ttaattggta aagaagtaga agtatctggg gaagaagatg aagatgaaaa cattgtagga
    68881 gtagtaaagt ccacatacat aaaagatggg gaagtacact tagaattaga agtagatgga
    68941 agtgacaaaa ctgtagatgt taaatatgaa aaattactta aaataggaga ggtagaggca
    69001 aattcaggag aagaaaatga ctcttcagaa caagaatctc cagaagaagt ataatattaa
    69061 atgggaaaag aggtaaattt atgataaaag caatgtattc aggtgtaagt ggaatgaaag
    69121 caaatcaaac aaaactagat gtaatcggta acaatgtagc caacgctgga actacttctt
    69181 ttaagaaaag ttcagctaga ataacagatt cattttatca aactgtacta tatgcaagtg
    69241 ctccaacagc ggcattaggg ggaacaaact taggacaagt aggtgtaggt agtaagatat
    69301 caagtataaa caaagatatg acacaaggaa atgtacaacc aactaataga ccatctgatt
    69361 taatgataga tggagatgga tatcttccag tagtaagaca aggaacagtt atgtatacga
    69421 gagatggttc ttttaattta gatacaggat ttaaagcagc tgatggtgct ttgaagaata
    69481 ttaaaggtgg aagacttgta aatggtgatg gatatatgtt acaaggtatg atttatgatg
    69541 gggaatataa agctgatact ggagaatttg ttaaaaaggg tgatgctaaa ggaaaagagc
    69601 ctattgtaat accacttcaa agtataagtc ctaaggatgg aacagttcaa aatgtactag
    69661 agtataatat atcaaaggat ggaacagtag aatttttatt gagtgatggt caaagaactc
    69721 aatttgtcta tgatatacct gatggtgcta aggtaggaga tacacctgct ggaatagata
    69781 aattaaaagg tacaatacaa aaagtgcaaa catatgcatt ccaaaatcca gcaggactag
    69841 atgcagaagg aggaaacttg ttcaagccat cagcaaactc aggagaccca caaatagcag
    69901 gagctacagg cacaataata caaggagcta tagaagcttc caatgtagat atagcagaag
    69961 aatttacaga aatgataata gcaagtaggt ctttccaagc aaacagtaaa ataatatcga
    70021 catcagacga aatacttcaa gaaataataa atcttaagag atagtaggta catattatga
    70081 taagagtaac ggatttaaac ggaagaaaat acatattaaa ttcagatctt atagtgagaa
    70141 ttgactccgt gccagaaagc aggattctcc ttacaacagg agaaaaaaat cttgtaaaag
    70201 agtcagtaga tgagatagta gataaagtaa taaagtataa aagaaaaata aatgtaggtt
    70261 atattaggag tgaaaaataa tgaaaaaaac agattcacta acattcattg gactaatatt
    70321 atctacagta ttagttttat ttggagcagt aaaaggaagt agttcaggat tgaaaagttt
    70381 tttcgatttt gcatctatat taatcacagt atttgggtca tttggagctt tgatgattac
    70441 atttactatt gacgatataa aacttataaa agatgctcta caatactcat tcaagacaat
    70501 gaatatatcg aaattagact tattaaatca atttaaaaca ctttctaaaa aagcaagaag
    70561 agaaggactt ttatctatag aaagtgatgt aatgaaaata caagacccat ttatgaaaaa
    70621 aggattagag ttatgtattg atggtcttga aataaatgaa ataaggtcta tactagagct
    70681 cgaaatagat tctgttgaag aaaccaataa cagatattct aaactattta aaacttgggg
    70741 gactttcgca cctgcatttg gtatgttggg aactctaata ggtttaatac aaatgttatc
    70801 cgaccttaca tctccagatt taatagcatc tggtatggga aaagcattaa ttacgacatt
    70861 ttatgggtct ttacttgcca atatcgcttt gaacccaatt gcatataata tagatgagaa
    70921 gactgaaaaa gaaatttatg taaaggaaat gatgctggag gggataataa gcatacaatc
    70981 tggagagagc agcatagtag ttgaggaacg tttagctaca tacctttcaa ataatgagaa
    71041 gttagaaatt atgaaatcca ataaaaatac agaaagagca atgagtaatg gcgcgtaaaa
    71101 aaaataagaa aaaggatgag ataaatccag atgcatggtt ggctacttat gcagatacga
    71161 taacactgat tcttacattt tttgtgttat tgtatgctac atcagttgta gatatggaaa
    71221 aatttaaaaa tatagcagat gcgttaaaag gtcagttttc tgggacaagt atgtttagta
    71281 caggttcaag tacaagtgag aaatctccaa tagagagtgt tttagtggat aaaaatgata
    71341 agtcaaattt agaacaggat ttaaaagata aagttaataa ttctaactta caaaatagtg
    71401 taacagtcaa agatgatagt agagggattt tactagagct agatgattca attttatttg
    71461 actctgggat ttctgaatta aaagaagata gtaaagccac tcttaataaa gtatacgata
    71521 tgataaagat gatgaaaaat aagatagtta tagaaggcca tactgataat gtacctgtaa
    71581 aatcaagtac gcatgaatcc aattgggatt tatcttctag tagagcagta agtgttgtaa
    71641 gatactttgt agaagaaaag ggcatggacc ctaaactatt ttcggcaaca ggatgtggag
    71701 agtaccaacc tttggtatca aatgaaacag caaagggaag agctgagaat agaagagtta
    71761 atatacttat aactattgac taggaggaag aggtttgttc aaaaataaaa aaattattat
    71821 aattattttg atactgatta ttttctcagc aggagcaggt ttttttatat taggagaagg
    71881 tggaaataaa caaattgaca agattgcagg tttgtttatt ccaacaggga aaggcaaaga
    71941 tgaagtaaag accgaaaatc ttgacttaga agagatggta ttgaagctag ctgatgaagg
    72001 tgtaagatat ttaaaagtat caataactgt atcttatgat tcttcatata aagatataga
    72061 aaaaaatacg cctttaatta gggataatat tataaattgt tttatggcaa aaagggcaga
    72121 tgattttact gctgataatt taaagaacat aaaagaagaa attaaaaata cattaaatat
    72181 acaactaggt gaaaatgtaa ttcaaaatat atatttcaca aatatagtag tgcaataaaa
    72241 ggatggtaag acatgatact ttatttacta aaaatattaa tatgtatccc aataatttta
    72301 atattgatag tcttatcttt aaaaattagc caaggaactt tattaaaaaa atataatgat
    72361 aaatatataa aaatactaga tattgtaaat ataagtaaaa acaatagcat aataatttta
    72421 aaaataggtg aagaaggatg cattatggca tcttcttctt ctagcatgag taaaataaaa
    72481 gatttgacca aagaagaaat attaagaata gaaaacgaca ttaaagaaag aaattttaaa
    72541 attcaagatt ttaaaatgga aagaattaaa aagaaatatg atttcagtag atatattgga
    72601 aaatttacaa aaaaggaaga taagtaaatg gaactattat caaaattacc tttggctgat
    72661 gtaccatata caagttcaat gcaattgttt ttatttctaa ctgcattaat gtttttacca
    72721 tttgtaatgt tcatgatgac aagctttgtc agaatagtta taagtttatc atttttgaaa
    72781 tcagcattag gagcacagca agcaattcca agtcaaattt tggtagggct tgcaatagta
    72841 ttgacaatat ttataatgag accagtatta aatgagataa acgaaaaggc attacaacca
    72901 tatatgaaag aagaagttac tatggaagaa gctatgaagg aagcagaagg acctattaaa
    72961 gaatttttat taaagcaaac cagacagaca gatttagatt tatttgtaga gcaagctggt
    73021 ttaaaagaaa agaaattaac tcgtgaaaat ataccattat ctgttgtagt tccagcattt
    73081 gctataagtg aactaaaaac tgcttttcaa ataggttttt taatatatat accatttttg
    73141 ataatagacc ttgttgtggc aagtgttttg atgtctatgg gtatgtttat gttacctcca
    73201 gttatgatat cattaccatt taaattatta ttatttgtaa tggtggatgg atggaacttg
    73261 atagtaaaaa cattgatatt gggatttgga taggagaaaa atagtatgag tgaatttatg
    73321 ataatgagtg ttcttaaaaa tggcatgttt acaggagcta tgattgcagc tccagtgcta
    73381 attgtttctc ttgtagtggg gcttttaata agtgtatttc aagccacaac tcaaatccaa
    73441 gagcaaactt tgacttttgt accaaaacta atagcaattc ttttagtagt agctattggt
    73501 ggaagctgga tgttacatac tcttattagc tttacttcgg agatattcaa tatgatgtct
    73561 ctcataacta aataagtagg atatatatga tttttgtatt tattagaata gtagcattct
    73621 ttggaacatt aaggatacta tttccagctg gtacacctgc tttatttaag tcgctctttg
    73681 caatcattat atcaatcttg atttcaagta ctatgcaaat tgaatatgca acaaatatag
    73741 acaacattgt attgtttacc ttatatggta taaatgagac cataactggg attatgcttg
    73801 gatatataac caatctatgt ttttatagta tcagaatggc tggttctatg atggaccaac
    73861 agatgggatt atcaatgatt aatatgtttg acccaaattc aatgactcag acaactttaa
    73921 tcaataatct tatgaactgg acagcactta tgatattttt tagcatggat ggtcatcatg
    73981 ttttaattag aggcataagg tatagttttg agttaattcc aatagggaaa tcattcatag
    74041 ataataatat agattatata ataaacatat ttgtgcagtg ctttttaact ggattcaaaa
    74101 tagcaatacc tattgtactt tgtctgctta tggcagattt tatattaggg cttatatcaa
    74161 gaagtgtacc tcaactaaat gtaatgataa ttggtatgcc attaaaaata ctggttggta
    74221 ttgcattatt tatcatatca atacctttaa ttgtcaatca aataagtcat ttattaagtc
    74281 aaataccaaa gatgtatgag ggaacttttg cactagctcc tatgtttttt atgggttcaa
    74341 cagataaaac agaagaagct actccaaaga aaaagggaga acaaagaaaa aaaggtaata
    74401 tagcaaagag taaagaatta cccattgcaa tgactctact tgcattcact ttattagtac
    74461 ctacattatt ttcatatgta gtgaatacac ttaaatcttc tcttaattat tttttgagtc
    74521 tagattttta tatgaacata aattattcaa gtatagagaa attagttata gcaggattaa
    74581 tggatttttt taagatattt ttaccaatag ctattccatt cttagtttta ggtatagtcg
    74641 caaacctatt tcaagtagga atactgttta ctggtgaaac tttaaaaccc aatttatcaa
    74701 aattaaatcc aattagtgga ttcaaaaaca tgttttctat gagaagtttg tcaaccttaa
    74761 taaaagatac agcgattata tctattttgg cttacatagg atatacattc ttccaagata
    74821 attatttaga tatattaaag ttaggtaaca tatacctgcc aactttaatg tacacagtta
    74881 aagatttagt atattcaata ttaagtaaga tttgtgtagc tatgatagtt atagcagttg
    74941 cagattatgt ttatcaaaga tacagtcata aaaagcaact tagaatgaca aaacaagaag
    75001 ttaaagatga atataaaaac tcagaaggag acccagaaat aaaagctaag ataaaacaaa
    75061 aacaaagaca aatttcgtct caaagaacca tgcaagcagt accaagtgct actgtaatag
    75121 taaccaatcc cacccactta tctatagcag tgagatatga aaaagggaaa gaccaagctc
    75181 cagtagtggt ggcaaaaggt gcagattatt tagcttttaa aataagggaa attgcaaagg
    75241 gaaatgacat acctataata gaaaataaac ctattgctag gttgttatat aagcaagtag
    75301 aaatagacca agaaattcca gaggacatgt atcaagcttt tgcagagata ttagtagcag
    75361 tatataaaat caaaaataga tacaaagtcc ccaaaaggta ggataagtaa tgaataagtt
    75421 taatttaaag gaaaatatgg acgtaatagt ggcatttggt gttgtaggga ttgttcttat
    75481 gatgatagtg ccgttaccta catttatatt agatatttta ctggcaatta acataagttt
    75541 atctgtgcta attttactaa tgacactatt tacaacaaat gtacttgatt tatctatatt
    75601 tccaacagtg ttacttgtga caacactatt tagattggga ttaaatcttt catcaactag
    75661 attgatttta acacagggat atgcaggtga agttatagag gcatttggaa gttttgttgt
    75721 aggtggaaat tacgtagtag gaataattat attcttaatt atattaattg ttcaatttgt
    75781 tgttataacc aatggttctg gaagagtatc tgaagtaaca gctagattta cgttagatgc
    75841 catgccaggt aagcagatga gtatagatgc agatttaaat gcaggagtta tagatgacaa
    75901 aactgctaga aaaagaagaa aagagcttca gcaagaagca gatttttatg gctctatgga
    75961 tggagcaaat aagtttgtaa agggagatgc catagcaggt cttatagtaa cagcaataaa
    76021 cataataggt ggaattgtaa taggagctgt aatgctgaat atgactctta tgggtgcagc
    76081 acagacatat gtaagactta ctatagggga tggtcttgta agccagatac ctgctctatt
    76141 aatatctaca tcagcaggta taatcgtaac aagagcttct actgatgaaa actttggtgg
    76201 attagtaggt aaacagttaa cagcaatacc aaaagcagta atgatgactg gctgtgttct
    76261 aatcgtactt ggtatgatgc ctggattacc taaaccagca tttttttcac taggtatagg
    76321 tgctatagca gcaggttact ttttaggaag agaaaagaaa gatactttag aagacttgga
    76381 gtttgaaaaa cctgatatgg taaatccaga taaaaatgaa gtagaagatg taacaaactt
    76441 aataaatgta gaatcaatag aagtagaaat tggatatggt ttaatatctt tagctgatga
    76501 atcagcagga ggagatttac ttcagagaat agcatcaata agaagacaat gtgcaataga
    76561 catgggtata gtcgtacaac ctataagaat aagagataat ttacagttaa atccaaacca
    76621 atacaatata aaaataaaag ggaatgtagt tggtgggtat gagataatgc ctaatatggt
    76681 tttatgtatg gatcctatga atcaaggatt tagtatattt ggaataaaga caattgagcc
    76741 tacttttgga atagaggcac tttggataga aagtgacaag gtagaagatg cagagctaaa
    76801 gggttataca gttgtagatt catccacaat acttataact cacttactag atataataaa
    76861 atcaaatgca cacgaattac tgggaagaca agaagttaag actattatag atgcagcaag
    76921 agaaaattat agtgctgtag tagatgaatt gataccagat ttaatgacac ttggtgaaat
    76981 tcaaaaagta cttaaaaatc tgttaagaga aaaagtaaat ataaaggata gagttacaat
    77041 acttgagaca cttgcagacc agtctagaaa tacaaaagat atagagcttc ttactgaata
    77101 tgtaagaata gctttggcta gaagtatttg taataattta gttgatgaag ataaggcaat
    77161 tgtagtggct acattgtctc cagaaactga agaattggta tctaataatt tacaaaggtc
    77221 tgtaaatgga acttatccag cagttgaccc agaaaataca aataaaatat ttgagagtat
    77281 acaagaagta atgaacaatg tatatttcaa tcataatata ccagtaatag tagtatcacc
    77341 aaagataaga gctccattta gaaaattagt tgaaattgta tatcctaatt tgactgtatt
    77401 atcattaaat gaaataccta acgatattaa aatcaaagca gaaggtgtgg tgagcatata
    77461 tgatgacgaa aaagtataca gctaacacaa ttcaagatgc tatgaatcta gccaaaatgg
    77521 aattgggtga caatattaca ttaatagata aaaaagaggt aagaaaatct ggaataagag
    77581 gcattttttc aaagaaagat attgaattga ctattggatg ggaaaagaaa gataatttag
    77641 aacaaaaaga tttaaaacga gagatagaac aactaaagtc aattataaat aatatggggt
    77701 ttgataataa aaatgataat gatatagata aaatatgcaa gaatttacta aacttagatt
    77761 taaatcaaga aattgtagaa tttataaaag ctgatttaca agaaatgaag ttcaatggaa
    77821 ttgatacaag taaaaattta gtagaaagtc taaagaaaaa gattaaaata gaaaatcaag
    77881 caataaatgg taaaattgct ttagttggac caccaggagt aggtaaaacg actacaatag
    77941 caaagttggc tgccaaatta gtttttgagg aaaataaaaa agtaggagta ataactatag
    78001 atacatacag gattggtgct gtagaacagt taaagatata tactgatata atgaatattc
    78061 cttttaaagg ggtaataagc cctgatgaga tggaattggc acttgatgag atgaaagatt
    78121 gtgatgttgt attaatagat acaacaggta gaggctataa aaactctatg caaatattag
    78181 aaatcaaaaa tcttatagat aaagctgaaa ctgataatat acatttagtt ttgaactgta
    78241 caacaagaga aagtgataca aaagcaatta tagattcata tagaaatgtg aattttaaaa
    78301 gcttaataat tacaaagtta gatgaaacaa taacatatgg ctcaatattt aacataatga
    78361 attatgcaca aaaaccaata tcatatatta caacaggaca aaatgttcct gatgatatta
    78421 taaaacctaa tgaagataag attataagat tactattagg agttgaaagt atatgataga
    78481 ccaagctcaa attttgagaa aaatggcaat ggaaaaaaga ggttctgatg agattatagt
    78541 agagaatgag aatatgccta agataattac aatagcttct ggtaaaggcg gcgttggaaa
    78601 gagtaatctc gctacaaatt tgtctatatg cttaaccaaa cttgataaaa aagttcttat
    78661 attagatgca gatataggaa tgtctaatat agatataata atgggggtaa atgtaaaagg
    78721 gactataatt gatgtaatta atggcgaaaa aaatatagaa gatataattt cacagactaa
    78781 gtatggtgta aatataatat ctggaggttc tgcccttaat catatagaag actttacaga
    78841 agctcaaaga aataagttta tacatagcat agaacagatt cacaatgtgg attttataat
    78901 aattgataca ggagctggta tgagcaaaag cctattgtca tttatatact gtagtactga
    78961 atttttctta ataacaactc cagaaccgac atcattgact gacgcatata gtttattaaa
    79021 agctataagt aattttggca taaagaaaag tgcaaatata ataatcaata gggtaattga
    79081 tttagaagaa gcgaaatcta catacaaaag aataaaaatg gttgtggaca aatttctaaa
    79141 ccttaatctg gaattgtatg gatatataat agatgacaaa aaagtaggtg tatgtgtaaa
    79201 aaaacagata ccattcattt tagaatatcc tacaagtatt gcatcaaaat gtattatagc
    79261 tatagcaaag agaatggtaa gtcagtcaag agaagatatt gttgataata aaagttttct
    79321 aagaaagatg tttagtatat ttaaaagcta aggaggcgta gttaatgaat agagaagaat
    79381 taataaaaga gaatatgcct cttgtaaaga gtatagcaag aaaatttttt ataccaggga
    79441 aaggttttga atatcaagac ttagtaaata gtggagtcat tggattgatt gatgcaataa
    79501 ataaatttga tactgaaaaa ggagcaaagt tttctagtta ctcttatata aagataaaat
    79561 ctgctatatt agatgaaatt agaaatcaaa gtccaatttc taaacataat ctaactaaag
    79621 taaataagta taatagagtg gtagaaaagt tgcaatctaa attattaaga gagccaactt
    79681 catatgaaat tgcaaaagaa ttaaaggttt cagaaaaaga acttcatgat atcgaaagta
    79741 atatagatat gttaaatatt gtatcattaa actatgtaat ctttgaagat acaaatgaaa
    79801 ctgtacaaga tgtaataagt gatagagaag aggaagctcc agaaaatata atagaagaag
    79861 aagaaaagtt agagattcta tccaaagcaa ttagtaattt aaatgaaaga gaaaaattaa
    79921 tactttcact gtactattat gaagatttaa atctaaagga gatagggaaa gtgctaggtg
    79981 tttcagaatc aagagtttca caactccaca gaaaatcaat aagaaactta agaaacaaga
    80041 taaaagaact taaatattct atatagatgg tgattgataa gatgatacaa attatattaa
    80101 tagtagtgtc tattttaata atagtaacta tagttataaa tttacagaag gaatcaaaaa
    80161 ataaagataa cagatacttt gataaaatat ttgagcaaga atatgaagca aatgatagat
    80221 taataattgc agaaaaaaga agattctttt tagacaaagt acttgcagaa aaaagaatta
    80281 atagtcatat aaaagtttat gaaaattata acctaataaa ggctaatgaa gaaagaaagg
    80341 aaaacatatt tatagaatca aaaaaggaag taagacaaga aaatgagtta tctcttaaag
    80401 tgaaacatct tataagttca ggttatgatg atgtggaaat atgtaagatg ctagatattg
    80461 gaaaggggga actgttatta ataaggagtt gttacaaaat ataaggatat tattatgtga
    80521 taaaaaagta ttcttaggaa taggtattgg tatattaata tcaactttat gtataatgct
    80581 ttttagtaat aatgatatga gtaaggcaga gatagaaaaa aaggccagag cgttaggcat
    80641 gaaatataca agtgagatga aagttttaga atagatgata ctgtttagac atttacaaaa
    80701 aaggaggtca taatgtgata agaggattat atacagcagt ttctgctatg ataactaatc
    80761 aacaaaagca aaatgttgtt gtcaataacc tagctaatat ggatacaaat ggatataaaa
    80821 gtaaacaact tttgactaaa agttttgatg aattaaagtt ggagggttac aataactacg
    80881 caaatggaac taaacaaaag cagattatag gcgatataag tccaggtatt tctatggatg
    80941 aaactatcac aaattttaat caaggaccta taaaaactac tgataataaa atggatgtag
    81001 ctattcaagg taagggattt tttctagtta gtgatgcagc tggaaatcaa ttttacacta
    81061 gaaatgggaa cttcagaaca gacaatcaag gtgaccttat aacaagtgaa gggtattatg
    81121 tacttgggac gaatactgct actggtgctg taggtcatat aaatgtagga aatcaaaaat
    81181 ttgaagtggc aaaagataat acaatatcac tagacggaaa tgctatgtat aaatttaata
    81241 ttgtagattt taataactac aataacttaa aaaaagaagg agataactta tattctggag
    81301 gaggagctat gaaagtaaat aatgcactta caatacaaag tgcgatagag tcctctaatg
    81361 tagatatggt atctgaaatt aataatatga tgacaatatc aagagaatat gaggcaaatc
    81421 aaaagataat tcaggctatg gattctaaat tagcaaaaat agcaagtgag attggttcag
    81481 taagataggt aataggaggt gaatttttat gtacacaatg ttttatacta gtaaaacagc
    81541 tttatcagca aatcaaagta aactagatat aatatctaac aatatagcaa attctgattc
    81601 aacaggatat aaaaaaataa atatggaata ttctgattta gtggatgaag tactaaatag
    81661 accatcatac cctacaaatg gtaaagatat atcgactgga acaggagcta aggcaacagc
    81721 tcccatgaga aattatgaac aaggtgcatt ggctcctaca gatagtaaga gtaatttggc
    81781 gatagatgga gaaggattct ttagagtgat aagaaaagat ggtacatatg catatacaag
    81841 aaatggtgga tttaatgtag atgctttagg taagattgta gatgataatg gaaatatatt
    81901 agatgtccaa tttgatgcag gatataacta taataataca aatatagata gtacaaacct
    81961 gacagtttca agaaatggag agctattcgt agataataaa aaaataggaa aaattaactt
    82021 atatcaacct ataggaactc aaaattttat atctgaagga gatagtttat ttgtcgcaac
    82081 tgatgcagca cagattaaac aagttgagaa agtcgatata gttcaaggct atagagagag
    82141 gtcaaatgtt tctttacaag aagaatttgt tgacttaata gccactcaaa gagcatttca
    82201 aatgaactca aagggaataa agacagcaga tgaaatgtgg caaatagcga ataatttaag
    82261 agctaaataa ttatgtaagg agaggaatat tcatgaatga tatgaaagag tacgattttg
    82321 gcaaacctca gagttattca agagaaaatt taacttgttt aaatttttta ttagctgaat
    82381 tttgtaaaaa atataaaaac tatataattt atgaacttaa gtgtaattct agtatggttg
    82441 ttgatagtat agaccaagta aattatcaga cttttttaga tagagtaact tcttcatgcg
    82501 tagtagtaca aaatgcaatg gaacctgtta tgaaaaactt ttcttttaga atagatagaa
    82561 gtgtagctga tatgtggatt gatataactt ctggaggaac tggagttgta aaggataatg
    82621 atagagagct tacagaactt gataaaaaag tgcttttaca ccttatggat gatttagtaa
    82681 gaaatatgca cttatttgag ggttttgaaa atatacaagt attggataca catacacata
    82741 ttaatttgcc acaattatgt tctccaactg caccagtatg cgttgtagat ttaaaagtgc
    82801 taaatgataa tgagtgtatt ggaagtgttt ctctttgttt tccatacaat ggtttagagg
    82861 ctctgttaga aagtatatct gttatagaat tttttgataa tgatgtagga gatgattcag
    82921 aggaatttac ccaaaaaatc tataatagtg tatctaatat agaattatca gttattgcag
    82981 agataggaaa agtatcaatt aatgttgagg atttacttaa actagaagtt ggagatgtaa
    83041 tagtaacaaa taaaaaaata aatgattata tagatatatt tgtagaaaat tcaaaatcat
    83101 acacagcaac accaggattt atatcaagta aaaaaggtgt aaaaataaat gatgctgttg
    83161 gaaaagaggt gtagttatgg acaatagtaa tcttatttca gatgaagaag caaagatgtt
    83221 attaaatgat aaagttgaaa gtgaagttga tggagatgat gagttagcct tagatgtctc
    83281 tgaagttaat cgaaataata tacaaaggat acttgacctt aagttagaat tatctgtagt
    83341 tataggaaga actaagatga ctctaagaga tattttaaat ttacataaag gttctcttat
    83401 tgaactggat actttagcag accaagatgt ggaaatacta atagataata aggttttggc
    83461 ttatggaaaa gtagtggtgg tagatttaaa ttttggtgta aagataacaa gtatagtaag
    83521 tgaagaagac atggtaaaat ctcttgttta gagataacat caattaatac ttaaggcatg
    83581 aggtggtact tattttaaac ttaaatgata taaaaaaaga tatactaaaa ctcaataaaa
    83641 aagactcatg ttctctatat aatgaatcta ttaataatat aaataataat tgtatatcaa
    83701 ctggattaaa atttttaaaa caagcaagag atttaaaccc agatgatgtt gatatattaa
    83761 atctcacagg tcttgtaaac ttactaaaat gtaattttga tgatgctgta gaaagtttct
    83821 ataagagttc actttgtgaa aaaactgctc tgtgtgaaaa gtatataaac atgcttacat
    83881 ctgaggagtt tttaattttc tttgaaaagt acaatcaact tataaggtta ataaataaag
    83941 gaatgtataa agaagctata caagggttta aactcataac tgaccaatac tgtgatttaa
    84001 tagaacctta tgagttgctt gccttactgt atgacaagga agaagaatat ataaaatttg
    84061 atgaatgttt agaagtattg aagattattg ataaggaaaa ttatttatta aatcaagaaa
    84121 ataacacatt agatatgtat aatagtgcta atatacaaac taaaagtaat ataaaagtag
    84181 atgattataa gaatgagttc ttacataaaa gtagtagtaa ccataaaatt aatgattata
    84241 atgatgtaac taaagaaaag agttcaagca aaaaccagaa aagttcagat tctaataaga
    84301 aaaaaagtat taaaaaaaat aagtacctat atatagccat aatattagga atattattag
    84361 taggacaaag tatatataat tcttataaga tgaataattt aactgataaa atatctaaaa
    84421 ataatgaaac taaaaatgaa gagtcaatag attctaactt gactaagaaa gaaaataata
    84481 tagaagaaaa tgaagatatg agtaaggctt ctaatataaa taagagtaat aaaaacatta
    84541 ataaagagga tgatgtaaaa tctaaaaaaa atactgtaga aaatgaagat gataaagatt
    84601 ctgacttatt tacagaggat gaattgatgt ctaaggcgaa tactttaaaa tcagaaaaga
    84661 aaactaaatc ttctatacaa ctatataaga aagttgcaga tataggtgaa aataaaggga
    84721 atacatctga agcaacttat caagttgcta ttctcagtga aaagttaaaa gactataaaa
    84781 ctgctgaaga atattataaa atgtatgtag aaaattactc agaaaaagat gcttattttg
    84841 atgaatctta ttataattta ggtatgatgt actataacaa tggtgattta aaaaattcta
    84901 aattgacatt aaagaagttg gttaataagg taccaaatag tatgtataat aattcaaaag
    84961 taaaagaaat tttaaaagaa gaatagttaa attagataag aaaaataaat tattttattt
    85021 taaaataata tgattataat atattgacat accattttaa aaaatttaaa atattaatta
    85081 taaaatgagg agggataaaa aatggaattt gaaaaaggga gtatttcaat tcatacagaa
    85141 aatatttttc ctataattaa aaaatggtta tactctgata aagacatatt tataagagag
    85201 cttataagta atggatgtga tgcagtaagt aaacataaaa gacttgtatc actaggagaa
    85261 atatcagaaa ataagtcatc agattataaa attacagtat ctgtaaataa aggagaaggt
    85321 acacttaaat ttattgacaa tggaattggt atgactgaag aagagataaa aaaatacata
    85381 aatcaagttg ctttttcagg tgctgaagat ttctttaata aatataagga taaaatggaa
    85441 gagtcaaatg atataatagg tcattttgga ttaggatttt attctgcatt tatggtgtct
    85501 aaaaaggtac aaatagatac actttcatat acagaaggag cgactcctgt aagatggata
    85561 tctgaaggtg gtacagaata cgaaatatct gaatcagatg ctagaaatga tagaggaact
    85621 actataacac tatttattga tgatgatagt aaagaatttt tagatgaatt tactgtaaga
    85681 ggaataataa ataaatactg ttctttctta ccagtagaaa tatatttaga agatgttgaa
    85741 agattagaaa gagaagctaa agaagcagaa gaaaaagcta aaaaacaaaa ggaagatgga
    85801 aaagaagaga ttgtagatgc aaaagtaatt gagcctttaa acgacactaa tcctctatgg
    85861 ttaaaatctc caaaagactg tactgatgag gagtataaag agttttatag aaaggtattc
    85921 aatgtatttg atgaaccttt attttggata catttaaatg tagattatcc tttcaattta
    85981 aagggtatac tttacttccc taaattaaaa aatgagtttg aactgactga aggaaaagta
    86041 aaattataca acaatcaagt gtttgtggct gacaatataa aagaagttat accagaattt
    86101 ttacttttat taaaaggagt tatagactgc ccagacttac cattaaatgt atcaagaagt
    86161 ttcttacaaa atgacaggga tgtaagcaaa atttctaaac atataattaa aaaagtagct
    86221 gataagttaa aatctctttg taaaaatgaa agagaagaat acaataagtt ttgggatgat
    86281 atacaaatat ttattaaata tggttgctta aaagatgaaa gtttctatga gaaggtaaaa
    86341 gaatgtatat tattcaaaac tattgatgat gagtatataa cattacaaga ttatttagaa
    86401 aagtgtaagg acaaacatga aaataaggta ttttatgtaa gtgataaaga acagcaatct
    86461 caatacatta aactatttaa agaatacgac ttaagtgctg ttgttttaaa ctcatcaata
    86521 gatactcatt ttatttcatt tatggaatat aaagagaatg gagttaagtt taatagaata
    86581 gatgcagacc tttctgatgt attaaaagat aaaaatgaaa ataaagatag tgaagaaaac
    86641 aaagaagaga tagctaagat agaaggtctg tttaaagaag ctgttggaga aagagtgaag
    86701 aattattctg tagaaggatt gaaaaatgaa gacactccag ctatggtgtt agtatcagaa
    86761 caatctatta gaatggcaga aatgcagtca agatttgctg gaatggattt aggaatgaat
    86821 tttgaagaag aaaaaactct tgtaataaat gagaacagtc caataatcaa aaaattggtt
    86881 tctcttaaag atgatgagga aaagaaagat aagattacgc ttatttgtaa ccagatagca
    86941 gatttagctt tactttctaa taaagaatta aagccagatg agttagattc atttgtacaa
    87001 agaagtaata agcttatgag tcttttgata gaattataag attgaatttg aatacattga
    87061 agcaaattta taaaaagtat tcaatatcag tgataagaaa gaagtgtctc aaaatgaact
    87121 tttcagttca tgaggcgctt tttttatgtg aaattaaatt tattttaatc atttcaacaa
    87181 tgaaaaatat atttatctct attttgagac agaccgttct ttattttttt atctttggtt
    87241 aatttttaaa tatttaagta ggttctaata aaaaactcta tttagttaaa tatagttaac
    87301 ttgatatata ataagataat acatataatt aagtaaaaga ttgtttttta gtttatgttt
    87361 aaatacataa ttacactttg ttaaaaacat aaaattatta ctaaagtaga aataggaggt
    87421 tttagcatga attttaatta taatttgcca gtaaatatct tatttgggag cggcagaatt
    87481 aatgatgtgg gaaaagaagt atctaaatat ggcaaaaaag tattgatagt aacaggtaaa
    87541 aatagtacaa agaaaactgg attacttgat aaaacaatag atttactaaa agactctaaa
    87601 atagaatatg aagtttttga tagagtagaa caaaatcctc ttataactac tatatattca
    87661 ggagtagaaa ttataaaatc aactggatgt gattgtgttt taggtcttgg tggtggaagc
    87721 attatggatg ctgccaagag tatagctttt tcttataaaa acccaggaga tttaaatgat
    87781 tatatatttg gaattagaca aggtgaagaa gctttaccta taatcttagt tccaacaaca
    87841 tcaggtacag gtagtgaagg aaattgtttt gcagtactta caaattcaga aactaaagat
    87901 aaaaaatcta taaagaagaa tagtatgtat gcaaaagcat caataattga cccagaactt
    87961 atggttacaa tgccaaaaca tataattgca tcagttggat ttgatgcact tgcccataat
    88021 atggaagcat atctttctaa tggaagaaac cctcttgcag atgtacaagc tatttatggg
    88081 attgaactta tatcagaaaa cctaataaag gtatataatg atgttaatga tttagaagca
    88141 tgggaaaaaa taacacttgc aagtactatt ggaggaatga cgattggtac agcgggtaca
    88201 gccttgccac atggaatgga gcatcctgta agtggtctta gagatgtaat gcatggaaaa
    88261 ggacttgcag ctttgactcc tactattata gaaagttcat gggatagtga tattgaaaga
    88321 tttggtaata tttcaaaggt attaggagga acttgtgcag aagattgttc agatgcaatt
    88381 agaaatttcc ttaaaaaaat agatttagat ataaagctaa gtgatttagg tattgaaaaa
    88441 tcagatatag attggttaac tgataattgt atgaaaatat cagttgcaaa tattaagaga
    88501 catccaaagt attttaataa ggaacaaata aaggaaatgt accataagtc tttataattt
    88561 gactttacat atttagtttt atataaaaat tataaattaa taataaaaaa ttataagtaa
    88621 ttaat
//
LOCUS       DAYAOO010000004        86334 bp    DNA     linear   BCT 12-OCT-2024
DEFINITION  TPA_asm: Clostridioides difficile isolate ST8-SSI-h139-18
            SAMN40601845-rid21577343.denovo.004, whole genome shotgun sequence.
ACCESSION   DAYAOO010000004 DAYAOO010000000
VERSION     DAYAOO010000004.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN40601845
            Sequence Read Archive: SRR28438827
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 86334)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 86334)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-MAY-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-MAY-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002157583.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002157583.1
            Genome Coverage       :: 163x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/11/2024 16:19:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 4,038
            CDSs (total)                      :: 3,963
            Genes (coding)                    :: 3,930
            CDSs (with protein)               :: 3,930
            Genes (RNA)                       :: 75
            rRNAs                             :: 6, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 60
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 33
            CDSs (without protein)            :: 33
            Pseudo Genes (ambiguous residues) :: 0 of 33
            Pseudo Genes (frameshifted)       :: 7 of 33
            Pseudo Genes (incomplete)         :: 25 of 33
            Pseudo Genes (internal stop)      :: 11 of 33
            Pseudo Genes (multiple problems)  :: 8 of 33
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..86334
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN40601845-rid21577343.denovo.004"
                     /isolate="ST8-SSI-h139-18"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Denmark"
                     /collection_date="2018"
                     /collected_by="Statens Serum Institute"
     gene            39..155
                     /gene="rrf"
                     /locus_tag="ACGI5H_000334"
     rRNA            39..155
                     /gene="rrf"
                     /locus_tag="ACGI5H_000334"
                     /product="5S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00001"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00001"
     gene            275..466
                     /locus_tag="ACGI5H_000335"
     CDS             275..466
                     /locus_tag="ACGI5H_000335"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427633.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF378 domain-containing protein"
                     /protein_id="HFG9696067.1"
                     /translation="MKKVALILAIIGALNWGAIGILGTDLIGSIFGGTYEMVSRIIYF
                     IVGLAGLYLIPSLMSDDRE"
     gene            621..2030
                     /locus_tag="ACGI5H_000336"
     CDS             621..2030
                     /locus_tag="ACGI5H_000336"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427634.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016831 - carboxy-lyase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="aminotransferase class I/II-fold pyridoxal
                     phosphate-dependent enzyme"
                     /protein_id="HFG9696068.1"
                     /translation="MFIINELNKIVNEEVISFHMPGHKKGQVYKKLGYKDILKNLYKM
                     DTTEILGTDNLHFPEGIIKNSQKKASRVFKSDYTCYLVNGSSCGIQSAIMSVCSPKSK
                     IITNRDCHQSVINGCILGDIDIEYVPCEISEETNVLKGISISNVIDIIDKNLDAKAVL
                     LTYPTYYGMTYDLEYICNYAHSKKMVVIVDEAHGAHLGLSERLPKTALEQGADIVVQS
                     THKTLPAFTQSSMIHIQGDRVDIDKILNMLRITESSSPSYLLLSSLELAVDIYENKGK
                     ELMEELLNNIITFKNKVDSNINIYDTNDKTKIFISSKNMGLTGYELENILRNKYNIQV
                     ELSNYYGVLLICTIGNTVEDFSSLETALNNIVKEDFKFEKLENKKYPVVIPKKILTPR
                     EAFYKTKKSVKIYDSIGKVCGECIVPYPPGISVISPGEVISKEIIDYLMFCHSKGMIV
                     SGLKDVDLNFIQIIDLEDI"
     gene            2161..2850
                     /locus_tag="ACGI5H_000337"
     CDS             2161..2850
                     /locus_tag="ACGI5H_000337"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892113.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dTMP kinase"
                     /protein_id="HFG9696069.1"
                     /translation="MKGKLIIIESGSDASGKATQTEILYERLKKEGYMIKKVEYPNYE
                     SPSSALVKMYLKGDFGKNASDVDPYIASTFFTADRYASFKTDWEEFYNEGGIIIADRY
                     TTSNMVHQASKMDICDREEYLNWLADYEFNLFKIPQPDCVIFLDVPIEFSKKLMENRK
                     NKITGEEKKDIHESDIEYLEKSYNNALYIADKYDWKKINCVLDNKLRSIESIHNEIYK
                     IVLDSIKPMER"
     gene            2853..3788
                     /locus_tag="ACGI5H_000338"
     CDS             2853..3788
                     /locus_tag="ACGI5H_000338"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421505.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HFG9696070.1"
                     /translation="MYFENIIGQDFAKKYLTNSIKKNKLNNAYMFEGMDGIGKKKFAD
                     ELSKLLLDYENLENSPDYVLIKPDGNSIKIAQIRNLQSDIVIRPHKDYKIYIINNAEK
                     MTVEAQNALLKTLEEPPNYAIIILVTNNKESLLETIKSRCDIIKFSPIPIEDLKRYLI
                     NTGIEEERAQLLAIFSRGSIENALNLSQSSEFSMMREDIQQYIQIMLDKNIVEILNIP
                     NNMEKYRGKIIALLDMMINYFRDIILLKENVNKNMLINVDKLVFIQNMSGKISYSQLS
                     KIIDIIEDAKSKIKSNCNFNISIQVMSLNIYEVIK"
     gene            3785..4678
                     /locus_tag="ACGI5H_000339"
     CDS             3785..4678
                     /locus_tag="ACGI5H_000339"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427637.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="stage 0 sporulation family protein"
                     /protein_id="HFG9696071.1"
                     /translation="MIKIVGIRFKSAGKIYYFDPVDFNIEQDMDVVVETARGLEYGKV
                     VVGPKDMDESELVSPLKPIIRIATEEDKKVYLENKEKAKETFELCQQKIKEHELTMFL
                     IDCEYTFDRNKLIFYFTAEGRIDFRELVKDLAAIFKTRIELRQIGVRDEAKSIGGLGP
                     CGRKLCCSSWLGDFQPVSIKMAKDQSLSLNPTKISGICGRLFCCLKYEHDVYSEAIEK
                     MPVVGALVQSDDGKGKVVEVNPLLEQIKVEFQDKTVKIYTREDIKILREPKKCDGCGG
                     KCKDNDGLDEATLRELKKLED"
     gene            4756..5502
                     /locus_tag="ACGI5H_000340"
     CDS             4756..5502
                     /locus_tag="ACGI5H_000340"
                     /EC_number="2.1.1.223"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427638.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008170 - N-methyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:0016430 - tRNA
                     (adenine-N6)-methyltransferase activity [Evidence IEA];
                     GO_function: GO:1904047 - S-adenosyl-L-methionine binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA1(Val) (adenine(37)-N6)-methyltransferase"
                     /protein_id="HFG9696072.1"
                     /translation="MQLKDSERIDDLQLKGLKIIQDTNGFCFGIDAVLLANFTKIKKD
                     AKVVDLGTGTGIIPILIAGKSEAKKIIGVEIQEDVYEMATRSIKLNGLEERVEIINED
                     IKYIDKVLDINGYHVVTSNPPYMHIDGIKNPNDKKAISRHEVRCNLEDVIRAASRLVM
                     PRGKFFMIHRPTRLVDIITLGRKYKLEPKVIQFVHPRPQKAPNLVLVQFVKDGRPELK
                     ILDPLYVYGEDGNYTKELKAIYNNKDIGEL"
     gene            5503..6336
                     /gene="rsmI"
                     /locus_tag="ACGI5H_000341"
     CDS             5503..6336
                     /gene="rsmI"
                     /locus_tag="ACGI5H_000341"
                     /EC_number="2.1.1.198"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435873.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008649 - rRNA methyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:0008757 - S-adenosylmethionine-dependent
                     methyltransferase activity [Evidence IEA];
                     GO_process: GO:0000451 - rRNA 2'-O-methylation [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA
                     (cytidine(1402)-2'-O)-methyltransferase"
                     /protein_id="HFG9696073.1"
                     /translation="MSGKLYICPTPIGNLEDITYRTLRTLKEVDLIAAEDTRHSIKLL
                     NHFEISKPLTSYHEHNKDSKGDYLINKLIDGENIALISDAGMPGISDPGEEIIKQAIQ
                     NNIEIEVLPGATAFVTALVGSGMDTHRFVFEGFLDRDKKVRKAQLEELKEESRTIIFY
                     ESPHRLKDTLKDMLKILGNRNISINRELTKKYQEIIRENIETTIKIFEEKEIRGEFVL
                     IVEGFHGEKSKKENYDGLTDREYVLKLIESGMNKKDAIKIVCKDRKLKKDVVYKQVLD
                     L"
     gene            6359..7063
                     /locus_tag="ACGI5H_000342"
     CDS             6359..7063
                     /locus_tag="ACGI5H_000342"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435869.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HDIG domain-containing metalloprotein"
                     /protein_id="HFG9696074.1"
                     /translation="MEIGKIIIESLKREDTHKIFIELDNKHELEKIIPKISCMKSVGE
                     CKYHVVNCFEHSINALKELEIVLNDKDFFPIHLRKHVSNYLNTYIEEGINKLHVLKLG
                     TFLHDIGKPDSMTLDETGRVHFTNHEKIGAQIIDNMGIKLELSTETYRLISKYVRYHM
                     ILLSLYKKNDLSRKELINVFNLVDEDTIGVIMLGYADIVSTVKLLGKSGEVSVLKTYM
                     EYILTNYLYKSNYTHV"
     gene            complement(7251..7679)
                     /locus_tag="ACGI5H_000343"
     CDS             complement(7251..7679)
                     /locus_tag="ACGI5H_000343"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007287587.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Lrp/AsnC family transcriptional regulator"
                     /protein_id="HFG9696075.1"
                     /translation="MDVTDYRIIEILQDDGRISMKDLGKIVGLTSPAVSERVKRLEES
                     GVIEGYKAIVNPDSLGRVIKAFIHISLPSNGYTEFIESAAKDPRIVECHHITGDDCLL
                     LKVIVKDMYELENVIDTIKKIGSTKTSVILSTPIQAKSIL"
     gene            complement(7716..9146)
                     /locus_tag="ACGI5H_000344"
     CDS             complement(7716..9146)
                     /locus_tag="ACGI5H_000344"
                     /EC_number="6.3.4.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004516 - nicotinate
                     phosphoribosyltransferase activity [Evidence IEA];
                     GO_process: GO:0009435 - NAD biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="nicotinate phosphoribosyltransferase"
                     /protein_id="HFG9696076.1"
                     /translation="MRNLTLLTDLYQLTMLNGYFEKNIHEDIVVFDMFFRKNACDGGY
                     TIVCGIDQVVEYIDNLHFSDEDLEYLKNLNLFSDKFLKFLKEFKFTGDIYAVEEGTIM
                     FPNEPLITVKAPLYQAQLIETALLTIVNFQSLIATKASRVCFAAQGDPVFEFGLRRAQ
                     GPDAGIYGARAAVVGGCAGTANVLAGKMFDIPIIGTQAHSWVQKFDNELEAFQAYADV
                     YPDKCLLLVDTYDVLNSGVPNAIKVFKNISEKGYKPMGIRLDSGDLAYLSKEAKKQLD
                     NAGFSDISITASNDLDEYTITSLKAEGATINSWGVGTKLITSFDSPSLGGVYKLAASC
                     EKGVLEPKIKISENPEKINNPGYKKVIRIYNEDNKAEADLIMLHDEVIDESKPLEIFH
                     PTYTWKTKVFTNYKVKELLKPLYIKGRCKYNKKAVLEIKNHVQYELSTIWEQYKRLSK
                     PHIYKVDLSRNLWYLKTQMIDSKKVL"
     gene            9278..9862
                     /locus_tag="ACGI5H_000345"
     CDS             9278..9862
                     /locus_tag="ACGI5H_000345"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421491.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="spore maturation protein A"
                     /protein_id="HFG9696077.1"
                     /translation="MIIIGKIWFYMVSIGIIGSLISKNMGELNKVILSETSKGIEFAI
                     SLAGIMALWMGIMNIAKESGLIEKIGQKLNPIMRRLFPSIPKGHKAMSYIVMNIALNM
                     LGAGNGATAFGLKAMSELQTLNNKKDTATNDMIMFMVINISSIQIIPFTIIKLRMDMG
                     AQNPSEIIFTTLFATIISTAVAIITCKFFQRRYR"
     gene            9878..10399
                     /locus_tag="ACGI5H_000346"
     CDS             9878..10399
                     /locus_tag="ACGI5H_000346"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427661.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="spore maturation protein B"
                     /protein_id="HFG9696078.1"
                     /translation="MEIFSNLLIPIIILYIVIYGKYKKIDVYDSFVKGAIDGLKAAWD
                     ILPYIIGIFLAIGIFKTGKGLDMLEWLFTPIANMMSIPKELIGLISVKPLSGSGALGM
                     YSELANRVGIGSLVEKMGATIVGSSETIFYTMAIYYGSLKIKNTRHTLSCAMISHVAG
                     VIAAVFICYVIFV"
     misc_binding    10465..10711
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            10795..12732
                     /gene="metG"
                     /locus_tag="ACGI5H_000347"
     CDS             10795..12732
                     /gene="metG"
                     /locus_tag="ACGI5H_000347"
                     /EC_number="6.1.1.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894056.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000049 - tRNA binding [Evidence IEA];
                     GO_function: GO:0004825 - methionine-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006431 - methionyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="methionine--tRNA ligase"
                     /protein_id="HFG9696079.1"
                     /translation="MSKPSFYVTTPIYYPSGGLHIGHTYSTVAADTIARFKRFCGYDV
                     KFLTGTDEHGEKIQKKAIEQGMSEIEYLDGMIKDIKALWNTMDISYDDFIRTTEKRHT
                     DIIQKIFTKLYEQGDIYKGEYEGRYCTPCESFWTESQLLEGNKCPDCGRETYLVKEES
                     YFFRLSKYEDRLKELFKDDSFCFPAARKNEMVANFLDKGLEDLSVTRTTFDWGIKVPF
                     DEKHVIYVWVDALCNYITALGYMTDNDEEFKKYWPANVQIVGKEIVRFHTIIWPALLM
                     ALGLEVPKQVFGHGWILFADDKMSKSKGNVVYPEPIIERYGIDTLKYFLLREFAFGQD
                     GSYTHRNFVTRINYDLANDLGNLISRTVAMVEKYNNGIIPTAKVSTDFDADLKEQAVS
                     TRENFEAEMDKMQFHEALESVWKLVRRTNKYIDETMPWALAKDETKKDELDTVLYNLC
                     ESIRIIATLINPIMNETANKIYEHIGIKGQDDITTWESTKTFGLIGENVKVFKGEPLF
                     PRLDVEKEIEELTKMFSGKPPVEEKPLEHKEEITIDDLDKIELRVGKIISCEKHPKAN
                     KLLVSQVKIGPETRQIVSGIAEYYKPEDLVGKEVTVVCNLKPVKLRGVESQGMILAAG
                     DDGDPYVLPFTQGAKDGCEVR"
     gene            12762..13532
                     /locus_tag="ACGI5H_000348"
     CDS             12762..13532
                     /locus_tag="ACGI5H_000348"
                     /EC_number="3.1.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898746.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TatD family hydrolase"
                     /protein_id="HFG9696080.1"
                     /translation="MLFDSHAHLNDESFDEDRDELIGSLKDKGVDLVVNPGADIETSI
                     TAIELAKKYDFIYSAVGVHPHDVSKLDDTAIETLRKLATENEKVVAIGEIGLDYYYDY
                     SPREEQKEWFKKQIELANELKLPIIIHDRDAHGDTFEIIKNTKNPEIGCVLHCYSGNV
                     ELAREYVKMGCYISIPGTVTFKNNKKTREVVREIPLERLFIETDSPYMSPEPHRGKRN
                     NPSQVSFVADKIAQEKGISYEEVCRVTKENAKKFFNIK"
     gene            13870..14301
                     /gene="phnG"
                     /locus_tag="ACGI5H_000349"
     CDS             13870..14301
                     /gene="phnG"
                     /locus_tag="ACGI5H_000349"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892105.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0015716 - organic phosphonate transport
                     [Evidence IEA];
                     GO_process: GO:0019634 - organic phosphonate metabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphonate C-P lyase system protein PhnG"
                     /protein_id="HFG9696081.1"
                     /translation="MYTVDSTKILINMNLEKLEKIYSMIKDTSSISIIKEPNLATVMV
                     RANESVKNTTFNLGEILVTECSVKVDESLGYGIVSENNNKKAIYLAVIDAVLHSNNSK
                     FDELKNYINKSVYEENLRYEQEIIDEFSLINKTKVQFNAMD"
     gene            14316..14891
                     /gene="phnH"
                     /locus_tag="ACGI5H_000350"
     CDS             14316..14891
                     /gene="phnH"
                     /locus_tag="ACGI5H_000350"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435864.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0019634 - organic phosphonate metabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphonate C-P lyase system protein PhnH"
                     /protein_id="HFG9696082.1"
                     /translation="MVNYTQEIYRKMLDSASFPGKLNNIDNINIENNTNLLNGAIGIA
                     ITLLDQEVTFYIENYTQKDIKNIRALTMSNQIDYRKSDYIFLDINSEVDILQIKIGSF
                     EYPDESATIVHQVNDLSTYSQTKYIKLDLSGPGIKSKNSIYINGIREEFIERLSSINK
                     DYPIGIDLILVDKKGEIAFIPRSSKLSWEVL"
     gene            14894..16009
                     /locus_tag="ACGI5H_000351"
     CDS             14894..16009
                     /locus_tag="ACGI5H_000351"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427680.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbon-phosphorus lyase complex subunit PhnI"
                     /protein_id="HFG9696083.1"
                     /translation="MAYVAVKGGEEAILQAKNILEFYRVKGDSLPIDVKQIEEQMSYA
                     VDKVMSEGSLYNKELSALAIKQAQGDILEASFYVRALRSTMPRITYSEPINTEEMRIK
                     RRISATFKDIPGGQYLGATRDYENRILNVELLEEDEKKNRHFRDSFINELETVDEIPE
                     FTKISNIFRKENLLQEEVCENKLEEVIDDITRNSLRFPVSRAAKLQALTRGESGVVSG
                     FAYAIVRGFGDEHPYISELRTGNVFIKIKHPIYEDEEITIGDMLVTECEIVSKASQNK
                     TENSKNNSEDKNKMSLGYGLCMGNNENKAISMAILDKSLEPNSEKLAQDEEFVLLHID
                     GIDSLGFISHFKLPHYVDFKADVERIKKFEEVSLGDI"
     gene            15999..16868
                     /locus_tag="ACGI5H_000352"
     CDS             15999..16868
                     /locus_tag="ACGI5H_000352"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729334.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-D-ribose 1-methylphosphonate 5-phosphate
                     C-P-lyase PhnJ"
                     /protein_id="HFG9696084.1"
                     /translation="MIYNYGFLDENTKKEIRRKILKAISIPGYQVPFGSRELPIAKGW
                     GTGGLQLTLSLIGKNDVVKVIDQGSDDSTNACNIRSFIASVSNVETTKDTLEATLIQT
                     RHRIPEEKLKSNQILIFQVPIPETLRIVEPSEVETRRMHSEEDYSRMWVYLYEDIVRF
                     NDISIAVEYPCKVNDRYLMNPSPIPRFDIKKLNMSDNLFLFGAGREKRIYAIPPYTKV
                     EPLEFEDYKFEEEKFEGKYCSLCNSTNTFLDEVYDSDTNEKYYSCSDTSYCEKVRLKN
                     NSIDVTIGGTWNE"
     gene            16861..17727
                     /locus_tag="ACGI5H_000353"
     CDS             16861..17727
                     /locus_tag="ACGI5H_000353"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894050.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HFG9696085.1"
                     /translation="MSKINDSKRLENIDKQVLIGRNINLIYGDGCEKCFESTGYESNN
                     ICKYCGSIVACNNVNLELYEGEVLGIVGESGSGKSTLLKILFFQEHANSGEVYISHYN
                     KDTNILELSDQKKRYIKNHFMGIVYQNPHLGLNLDFSSGGNIAEKLLMANLYNVEKIR
                     DRGKELLIKTNIPVERIDHKPKYFSGGMQQRVQIAKALSNNPPILLLDEVTTGLDVSV
                     QAEVLDLIREIQREFKISMIVVSHDFDVIKMLADRTIVMKNGSVIESGLTDQIMEDPQ
                     HPYTQQLINSLL"
     gene            17768..18481
                     /locus_tag="ACGI5H_000354"
     CDS             17768..18481
                     /locus_tag="ACGI5H_000354"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892101.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphonate C-P lyase system protein PhnL"
                     /protein_id="HFG9696086.1"
                     /translation="MKETILEVNNFSKDFELHALNKTITACSNISFEVSKGEFLGIIG
                     KSGAGKSTILKSIYKTYIPTTGEIIFNSEIYGNVDLAKIGDREMINLRKKEIGYVSQF
                     LKTLPRITAIELVVHSLIESGFEKDCSYDMAKDILNQFEIKENLWDAYPNNFSGGEKL
                     RLNLAQAMVKKPRLLLLDEPTASLDNQSKIYVKEKMLELKSQGTTMIGIFHDIEFMET
                     VIDKTFTMTKGTISESGVA"
     gene            18482..19651
                     /locus_tag="ACGI5H_000355"
     CDS             18482..19651
                     /locus_tag="ACGI5H_000355"
                     /EC_number="3.6.1.63"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427691.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016810 - hydrolase activity, acting on
                     carbon-nitrogen (but not peptide) bonds [Evidence IEA];
                     GO_process: GO:0019700 - organic phosphonate catabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-D-ribose 1-methylphosphonate
                     5-triphosphate diphosphatase"
                     /protein_id="HFG9696087.1"
                     /translation="MIKLIHNANIVLEDMILENGHLIIEGDTIKKVSNDKIDYAFDFN
                     EIDEIIDAKNLYVIPGIIDIHSDAIEKEIEPRPSTLLPFNMAFYELDKKLPANGITTV
                     YHSISLGDGVGVRSIDNSLKMIKNIDSYKNIDSKSINHKVHLRYEVLYYEGLEKVLEL
                     LDENKIDYLSIMDHSPGQGQYTNPTFYKEYATKVWGVTENYVDTWLDDLVNLHDNLDW
                     NKIANIIGIAKTKNINVASHDDDTLEKMDFIKNIGINVSEFPITLEVAKHSKKLGVLT
                     CLGAPNIVRGKSHNNNLKAMDAILEDCCDIVCSDYLPSAMIKSMCIVAERINNLNKAV
                     SLFTSNPAKAVGIYDERGSIKENKKADLVLVDIDSEYPKVVNTIVNGKTVYKREV"
     gene            19655..20491
                     /locus_tag="ACGI5H_000356"
     CDS             19655..20491
                     /locus_tag="ACGI5H_000356"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427695.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PHP domain-containing protein"
                     /protein_id="HFG9696088.1"
                     /translation="MLTELHCHTSISDNNFTTEEIIKKAAEKNINILAITNHDTLSGL
                     DEALVLGEHYGITIIPGIEISAYDYKNRKRVHILGYNIDLNSQEIKNLCNPMVCDRHK
                     ASVKMVNKIIDLGYKISLEDVKKYSSKTGIFKQHIMKALIDKGYTDNIYSSLYKELFH
                     RGNGKVYVSLKYVDYRDAIKAIKNSGGICVLAHPGQMDNFSAIEEMVKVGLDGIEVYH
                     PSHNKELEKESLSYAKKYNLVVTGGSDYHGFYSQHNYELGSKSLNKEDLFKFRLALGG
                     VL"
     gene            20492..21487
                     /locus_tag="ACGI5H_000357"
     CDS             20492..21487
                     /locus_tag="ACGI5H_000357"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861991.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HFG9696089.1"
                     /translation="MSFLQVKNVGKSYGQVKVLKDISIDIEKGEFICLLGPSGCGKST
                     LLRIIAGLEDKHGGKIIINDKDMTNSPPESRNFGIVFQSYALFPNMNVYKNIAFGLEN
                     KNISKSNIDKKVKEVLEVVELSGYEKKYPSQLSGGQQQRVALARAIALEPDFLLLDEP
                     LSALDAKVRLKLREQIRSLHRKLGITTIMVTHDQEEALCLADKMVVMNRGEIIQVGTP
                     KEVYKNPETPFVADFIGTINFIDDGINKIAIRPEDIKVESNRDSKDKDIKVGEILDIE
                     FRGFNYRITVEYRSKQMKLDVVSKVAEQMKLCIGSKINFKIPKEGIVQYKSEGCA"
     gene            21505..23193
                     /locus_tag="ACGI5H_000358"
     CDS             21505..23193
                     /locus_tag="ACGI5H_000358"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894042.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0033225 - ATPase-coupled
                     2-aminoethylphosphonate transporter activity [Evidence
                     IEA];
                     GO_process: GO:0033223 - 2-aminoethylphosphonate transport
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="putative 2-aminoethylphosphonate ABC transporter
                     permease subunit"
                     /protein_id="HFG9696090.1"
                     /translation="MITSKNKRRISDSTIQKYFLIFSVIVLIVFILFPLVSLLKNAFM
                     DTSGNFIGISNFSKYVENPSLIASFKNSIFVSTVSSLISLCLAFIYSYAITRTNIKFK
                     EFFKTMGMFPLFAPTMLYGISLIYLFGNKGIFTTMGLEVPLYGPLGIIISQILFTFPQ
                     AFLILSVALSMADYRLYEAADSLGASEFKKFCKITIPGIKYSLLSSFFVSFILAFTDF
                     GAAKVVGGNYNVLATDIYKQVVGQFNIPMGATVSMVMLIPVLIAFTLDKMASKKQGMT
                     ITAKSMPYKIKENKFRDRVFLIVCSFITLLIFILIFVSVIGSVIKLWPYNLSFTMEHY
                     TFKGILGSGIKTYLSSLKISTLTAIFGTIFVFFSAYMIEKVDKFPKLRQTAYLLSMIP
                     MALPGLVLGISYITFFNSASNPLNFLYGSTAILVIVNVVHFYSVCFITSNSSLKMLDK
                     EYELVAKSINIPFYKVFFNITVPMSITSILEIVVYYFVNSMVTVSALIFLYTPQTQTA
                     SISILKLDEIGYIGPSAAMAVLVLLTNIIVRLLYEFVTKKLKNNTQKWQQKDVA"
     gene            23205..24272
                     /locus_tag="ACGI5H_000359"
     CDS             23205..24272
                     /locus_tag="ACGI5H_000359"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898733.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009897 - external side of plasma
                     membrane [Evidence IEA];
                     GO_component: GO:0030288 - outer membrane-bounded
                     periplasmic space [Evidence IEA];
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0033225 - ATPase-coupled
                     2-aminoethylphosphonate transporter activity [Evidence
                     IEA];
                     GO_function: GO:0033226 - 2-aminoethylphosphonate binding
                     [Evidence IEA];
                     GO_process: GO:0033223 - 2-aminoethylphosphonate transport
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="putative 2-aminoethylphosphonate ABC transporter
                     substrate-binding protein"
                     /protein_id="HFG9696091.1"
                     /translation="MKFKKLVSLGVLSTLLLSVITGCSTDSSGSDSKSDSKTKGDLTV
                     YTAIEEDSIEPYLATFKEKYPDIKLNIVRASTGDITARLLAEKDNPQADVVWGVAATS
                     LLVADDQGMLEPYAPKGSEEIESAFKDDKEVPSWVGIDAWMTGITVNTKELSDKNIPV
                     PSSYEDLIKPEYKGLISMPNPSSSGTGYLTVSALIQIMGEEKAWQYMDKLHENIGVYT
                     QSGSAPATSAASGEYPIGISFGYRGIKLKEEGYPVEVVFPKEGSGWDIEANALVKKDN
                     IKEASKVFLDWAISKDAMNEYSKNYAVTTISTGNPIPEGFPKKPLEQMIDNDLKSAAK
                     NREDILNKWISKYDGKTEKES"
     gene            25036..26103
                     /locus_tag="ACGI5H_000360"
     CDS             25036..26103
                     /locus_tag="ACGI5H_000360"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898733.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009897 - external side of plasma
                     membrane [Evidence IEA];
                     GO_component: GO:0030288 - outer membrane-bounded
                     periplasmic space [Evidence IEA];
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0033225 - ATPase-coupled
                     2-aminoethylphosphonate transporter activity [Evidence
                     IEA];
                     GO_function: GO:0033226 - 2-aminoethylphosphonate binding
                     [Evidence IEA];
                     GO_process: GO:0033223 - 2-aminoethylphosphonate transport
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="putative 2-aminoethylphosphonate ABC transporter
                     substrate-binding protein"
                     /protein_id="HFG9696092.1"
                     /translation="MKFKKLVSLGILSTLLLSVITGCSNVSSGSNLKSNNKTKGELTV
                     YTAIEEDSIDTYLATFKEKYPDIKLNVLRLSVGGITARLLAEKDNPKADVLWGVAATS
                     LIILDDKEMLEPYAPKGFDKVNSAFKDDKKVPSWVGIDAWMTGITVNTKELKAKNISA
                     PSSYEDLIKPEYKDLISMPSPASSGTGYLTVSELIQIMGEEKAWQYMDKLHKNIGVYT
                     QSGSAPAILAASGEYPIGISFGNRGIKLKGEGYPVEVVFPKEGSGWEIESNALVKKDN
                     IKEASKVFLDWAISKDAMNEYSKNFAVTTIDTGNPVPEGFPKNPLEQMIDNDLKSAAR
                     NREAILNKWIEKYDGKTEKES"
     gene            26295..26825
                     /gene="rnmV"
                     /locus_tag="ACGI5H_000361"
     CDS             26295..26825
                     /gene="rnmV"
                     /locus_tag="ACGI5H_000361"
                     /EC_number="3.1.26.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898732.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0043822 - ribonuclease M5 activity
                     [Evidence IEA];
                     GO_process: GO:0006364 - rRNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease M5"
                     /protein_id="HFG9696093.1"
                     /translation="MIKEIIVVEGRDDVTAVKRAIDAELITTGGFGFPKGVMERIKAA
                     NERRGVIIFTDPDFAGEKIRKKIASEVPGCKHAFLPREEAKKDGDIGIENATPQSIIA
                     ALNKVRTENTEKRDEFKQVDLIRNGLIGNEEASLRRDALGKILGIGYGNAKQFLNRLN
                     NYGVEREEFIDALKQI"
     gene            26996..27865
                     /gene="rsmA"
                     /locus_tag="ACGI5H_000362"
     CDS             26996..27865
                     /gene="rsmA"
                     /locus_tag="ACGI5H_000362"
                     /EC_number="2.1.1.182"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892086.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000179 - rRNA
                     (adenine-N6,N6-)-dimethyltransferase activity [Evidence
                     IEA];
                     GO_process: GO:0006364 - rRNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA
                     (adenine(1518)-N(6)/adenine(1519)-N(6))-
                     dimethyltransferase RsmA"
                     /protein_id="HFG9696094.1"
                     /translation="MDRLSSHNATKEVVQKYNFKFSKSLGQNFLIDSNIIDKILSGAR
                     ITRGDNIIEVGPGIGTLTREMGKIAEKVVAIEIDRNLIPILKDTLSDLDNTEVVNQDI
                     LKVDIQELVKDKLNGGPVKLVANLPYYITTPIVMKFLEEDIPVTDIVVMVQKEVADRM
                     NAIPGTKDYGALSIAVQYYCDTEIVAKAPRHMFIPQPNVDSTVIGLHVRDKRKYDVHN
                     EDIFFKTVKASFGQRRKTLLNSLGGLGFLNKDEIREVLKEANIDEKRRGETLSIEEFS
                     VLSNIINTKVSSK"
     gene            27931..29193
                     /locus_tag="ACGI5H_000363"
     CDS             27931..29193
                     /locus_tag="ACGI5H_000363"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729292.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9696095.1"
                     /translation="MGSKRKFKRDYIILEAKDINFRYKERVLPKAFAKVEVNDEKAII
                     ALYVENLKYVKDGYKAVAIKDDHGLIDLGNIILNEQGRGEFVLDLEDYDDEIKGIALL
                     YERNIPLIGFKGNKLENYEDILFQEVEEEEYEEYEELEEEDEEIEENEESDRDEDSEE
                     EYIIEEYDEDEYEDYWEDDEDIEEGELKARTEVEDSDDEEIEEFNNYKEIENYNRVKV
                     QEEYIDIEYDEEEEEEEVFEVNREEDRFVSSKPTKSKKVQKDQNNIEKIKRANGVSQG
                     ESGNKQTSTLLMPRQIKKGLKLFKEVKPFVTDYIDKTRWWKIEINPTTLCGYTMPYLG
                     YLNVLNYTMYSDAVLHSYKYRHYLFGVQYDEYNKRKHYIYAIPGNRNEQPDNGSTGFL
                     RYQACDNRTNSLGYWLCFIDSRQRNIVR"
     gene            29344..30459
                     /locus_tag="ACGI5H_000364"
     CDS             29344..30459
                     /locus_tag="ACGI5H_000364"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729293.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="M20/M25/M40 family metallo-hydrolase"
                     /protein_id="HFG9696096.1"
                     /translation="MINEQRILNEFLELVQIDSLSLKEGNVAKVLVKKLEEIGCSVVI
                     DNAGEKANGETGNIIATLKGNKEGKKILFSSHMDTVTPGIGVKPIVDEANGIIKSDGT
                     TILGSDDKAGIAAILEGLRYINENNIEHTDIQVVFSICEECGLVGAKNLDYGKIDSEY
                     AFILDSGGSPGEIIVKAPAQDVINVKILGKTAHAGLEPEAGISAIMVAARAIENMNLL
                     RIDEETTANIGIINGGTATNIVTGEVNIVAEARSLKENKLDVQTKHMVETFEKAAKDF
                     GAQIEIDVNRAYTPIDVSEDSEIIKLAKKAFSNLGIEGHTESTGGGSDTNILSKNGIE
                     AITLGIGMKNAHTLSEHIAIKDLYDSAKMVVEIIKEA"
     gene            30645..31541
                     /locus_tag="ACGI5H_000365"
     CDS             30645..31541
                     /locus_tag="ACGI5H_000365"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425940.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008324 - monoatomic cation transmembrane
                     transporter activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cation diffusion facilitator family transporter"
                     /protein_id="HFG9696097.1"
                     /translation="METRYEEANKITIQSILWNIVLTIIKVIAGVIGNSSAMIADGLH
                     SASDIISSIGVLIGNYVSSRPGDREHNYGHEKAETLVSFVLSILLIFVSITIGIEAIK
                     SLFNLDALSVPSILPLVVSVISILIKEYQYRITIKVAKKINSPALKADAWHHRSDALS
                     SVAAFIGIGGSILGFKPLDPIASVVVAIFVAKVGISILISSVNELMDVSVDEEEIKEL
                     KFIVADTEGVKNLGDIKTRKHGAMAYVDLTICVDENLTVKQGHDIATKLEKHIIKHME
                     FVKGITVHVEPCTNCQGNKCNN"
     gene            31611..32408
                     /locus_tag="ACGI5H_000366"
     CDS             31611..32408
                     /locus_tag="ACGI5H_000366"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425938.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9696098.1"
                     /translation="MSKKRKLKKKAAILIGVVVFFIIYFISFRIGINMEKDKSEVPKK
                     VEKEEEDNRSLRTQIKEKKKVYISDKNIENIKIEEDMWDEIKLFFSDFKKVRNTTSSY
                     EAVYEGYSDDGVKFSTDLNFFRVYTVNKEEYYKVPVSSKDAFKKLLDESIYTSFDLLS
                     HYKDWKEVTITHGKEIKKVHRWKFDDLAHKMISKRVVGKVQPEKSKERSDYNFTINIK
                     GDNFDVKVDTMGKDYVKVTSKKNVSYYEVHTSLFDYLKNEIFEIGKK"
     gene            complement(32463..33815)
                     /gene="murC"
                     /locus_tag="ACGI5H_000367"
     CDS             complement(32463..33815)
                     /gene="murC"
                     /locus_tag="ACGI5H_000367"
                     /EC_number="6.3.2.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421457.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008763 - UDP-N-acetylmuramate-L-alanine
                     ligase activity [Evidence IEA];
                     GO_process: GO:0009252 - peptidoglycan biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramate--L-alanine ligase"
                     /protein_id="HFG9696099.1"
                     /translation="MNIHFIGIGGISMSALAEICINKGYQVSGSDSNESYLLDKLRDQ
                     GATIYIGQKKDNISDDVNMVVYTAAVHPDNEELVAAKEKNKLVMNRATFLGQIMREYK
                     NSIAVSGTHGKTSTTSMLSTIFEYADLDPTILVGGNLSMIGGNVKIGNSNHFITEACE
                     YVDSFLNFNPKISIVLNVEEDHLDYFSGIDEIKASFNKFGKLLPPEGYFIINGDDENI
                     DDILYDVKATIIKYGRDSDNDAVIKDIHFDNSGHGIFRIEYEGRDLGEFELSVYGLHN
                     IYNASSAIMAALVSGIDLETIRKNIKIYKGVGRRFETKGYYKNALVVDDYAHHPTELK
                     ATLAAAKKLKKSTLWCIFQPHTYTRTKSLLGEFSEAFYAADKVIITDIYAAREKDPGD
                     IHSKDLVEKLYQNNVDAIYIKEFEDIVKYLRENVKDNDLVITAGAGPIYKVADLLVEK
                     "
     gene            34034..34912
                     /gene="purR"
                     /locus_tag="ACGI5H_000368"
     CDS             34034..34912
                     /gene="purR"
                     /locus_tag="ACGI5H_000368"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421455.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA];
                     GO_process: GO:0009116 - nucleoside metabolic process
                     [Evidence IEA];
                     GO_process: GO:0045892 - negative regulation of
                     DNA-templated transcription [Evidence IEA];
                     GO_process: GO:0045982 - negative regulation of purine
                     nucleobase metabolic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pur operon repressor"
                     /protein_id="HFG9696100.1"
                     /translation="MKFKRTERIGAIVKILSDNPNKIYTLSYFTNQFNAAKSTISEDL
                     LVVKNVFEKLHLGKVITISGAAGGVKYIPKTSIAENAEFLMELCERICDKSRILSGGF
                     LYLIDLIYDPTIAAKIGKIFASNIEYVDADYVVTMETKGIPMALMTAKAMNLPLVIIR
                     KDIKVSEGPTLSMTYVSGNSSKVESMSLPRKALKPDSKVIIIDDFMRGGGTIKGMVDL
                     MNEFGAEVIGTGVFISTTNPSEKMVKDYISLIQLDVNGDKIVVEPNLKTFKDEYRNED
                     LDEEEDSEFEFEIDED"
     gene            35068..35346
                     /gene="spoVG"
                     /locus_tag="ACGI5H_000369"
     CDS             35068..35346
                     /gene="spoVG"
                     /locus_tag="ACGI5H_000369"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421453.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0030435 - sporulation resulting in
                     formation of a cellular spore [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="septation regulator SpoVG"
                     /protein_id="HFG9696101.1"
                     /translation="MKITDVRVRKLTEEGKMKCIVSITFDNLFVVHDIKVIEGHNGLF
                     IAMPSRKVGEGNFRDIAHPINAEMRQVLEDAVLQAYHEALVQWEVAAE"
     gene            35559..36938
                     /gene="glmU"
                     /locus_tag="ACGI5H_000370"
     CDS             35559..36938
                     /gene="glmU"
                     /locus_tag="ACGI5H_000370"
                     /EC_number="2.3.1.157"
                     /EC_number="2.7.7.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898727.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000287 - magnesium ion binding [Evidence
                     IEA];
                     GO_function: GO:0003977 - UDP-N-acetylglucosamine
                     diphosphorylase activity [Evidence IEA];
                     GO_function: GO:0019134 - glucosamine-1-phosphate
                     N-acetyltransferase activity [Evidence IEA];
                     GO_process: GO:0006048 - UDP-N-acetylglucosamine
                     biosynthetic process [Evidence IEA];
                     GO_process: GO:0009252 - peptidoglycan biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional UDP-N-acetylglucosamine
                     diphosphorylase/glucosamine-1-phosphate
                     N-acetyltransferase GlmU"
                     /protein_id="HFG9696102.1"
                     /translation="MNFKAIILAAGKGTRMKSKYPKVIHKVCGKEMVNHIIDVSKKSG
                     VKDTVVILGHEADVVKEKLAEEIIIAMQTEQLGTGHAVKMAKEYINDEDTIVVLCGDT
                     PLIKEETLKRLFEYHIENKYHATVLTTRVGNPTGYGRIIRDKKGDLLKIVEQKDANSE
                     EKMISEINSGIYCFNGKSLREALDLLNNNNSQGEYYLTDTAKIMRDKGLKVGAFAGST
                     IEELMGVNSRVELSKAEEIMRRRINESHMVNGVTIIDTNSTYIESDVMIGNDTIIYPG
                     VMLQGKTRIGSDCIIGMNSSITNSEIGDGTEIKNSTIIDSKVGENSTVGPYAYLRPKS
                     DLGNNVKIGDFVEVKNAIIEDGSKASHLSYIGDAHVGKNVNIGCGVVFVNYDGKNKFK
                     SIVKDNAFIGSNSNLVAPVVVEEKGYIATGSTITHDVPDGALAIARERQVIKEGWVEK
                     KNQKDDQSK"
     gene            37033..37983
                     /locus_tag="ACGI5H_000371"
     CDS             37033..37983
                     /locus_tag="ACGI5H_000371"
                     /EC_number="2.7.6.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421448.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0002189 - ribose phosphate
                     diphosphokinase complex [Evidence IEA];
                     GO_function: GO:0004749 - ribose phosphate diphosphokinase
                     activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016301 - kinase activity [Evidence IEA];
                     GO_process: GO:0016310 - phosphorylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribose-phosphate diphosphokinase"
                     /protein_id="HFG9696103.1"
                     /translation="MNTSGSEIKIIAGNSSKELAQKIADYIGVSVLDCEVGTFSDGEI
                     CVNMNETVRGCDVFVVQSTNSPVNDNLMELLILIDALKRASAGRITAVIPYYGYARQD
                     RKAKARDPITAKLVANLITAAGADRVLTMDLHAAQIQGYFDIPLDHLLGGTILANYFN
                     EKKIEDLVVVSPDLGSVTRSRKFANTLNGEVPIAIIDKRRPKANVCEVMNLIGDVKGK
                     NVILLDDMIDTAGTIVNAANALKEFGAKDVYACCTHGVLSGPAIERIANSEISELIVL
                     DTIQLPEEKRIDKIKIKTVAPLFGDAIRMIFSNESVSKLF"
     regulatory      38821..38906
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF01786"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="cyclic di-GMP riboswitch class II; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /bound_moiety="cyclic di-GMP"
                     /db_xref="RFAM:RF01786"
     gene            39068..39589
                     /locus_tag="ACGI5H_000372"
     CDS             39068..39589
                     /locus_tag="ACGI5H_000372"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421446.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type II secretion system protein"
                     /protein_id="HFG9696104.1"
                     /translation="MKLKKNKKGFTLVELLVVIAIIGILAVVAVPALFSNINKAKVAS
                     VESDYSSVKSAALSYYSDTNKIPVTPDGQTGLSVLETYMESLPDKADIGGKYKLIKVG
                     NKLVLQIGTNTEGVTLTEAQSAKLLSDIGENKIYTSATTNSLGNPLTSNTKIDNNVLY
                     IVLIDNTVMDTTK"
     gene            39740..41416
                     /locus_tag="ACGI5H_000373"
     CDS             39740..41416
                     /locus_tag="ACGI5H_000373"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898724.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0009306 - protein secretion [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GspE/PulE family protein"
                     /protein_id="HFG9696105.1"
                     /translation="MAKKVRIGDKLVEKGYITEEQLKWALSEQKNSGKRLGEFLVQEG
                     LIDSNLLISVLKELLDIESIFLEGTEIDTLATKMVPENICKRYTVFPFKIDGNKICLA
                     MSDPQDREAVQDVRRMSGKDVEIFISSTEDINKAIGHAYAHSEINKAMTEYNKNRTGG
                     VRETVILEEDVNAAPIVRLVNNILENAVRMEASDIHIEQSENYMRVRFRIDGMLREYM
                     RMNSAPYKAVISRIKIMSDINISEKRIPQDGRIYLKVDNKPIDFRVSTMPTNRDEKIA
                     MRVLDKSNFMVSKEVLGIDEHGSKIYDELINTPYGLILVVGPTGSGKTTTLYSMLNQL
                     NTENRNLLTIEDPIEYELPGVNQSQINEKAGLTFASGLRAFMRQDPDIIMVGEIRDTE
                     TAEIAIRASLTGHLVLSTLHANTAVGAISRLLDMDVESFLITSSVLGVISQRLTRKIC
                     EHCKVSYEADIGEKKALGIDVNESVTIYRGKGCERCNNTGYKGRLGIFEMLEITPEIK
                     ELIDSSANQREILKMARKQGMVSLKEDIVKKVLNGKTTVEEMIRIILMTD"
     gene            41428..42636
                     /locus_tag="ACGI5H_000374"
     CDS             41428..42636
                     /locus_tag="ACGI5H_000374"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421443.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type II secretion system F family protein"
                     /protein_id="HFG9696106.1"
                     /translation="MKSFKYTVIKEDGKKQTDVIEANDFNEARNLLRKRNLRVIEIKE
                     SKNKNIRLSSRKRKKDLGADQISHFCRQFAIIVSSGINSISGLETLARRSTNITLREE
                     INRIVAEIKVGSTIADSMLSSKSKFPKLLGAMVATGEATGKLDEVLKSMASFYASEHR
                     VKQKLRNAATYPLIVLISSFIMIFIFTTFMVPKMINSITTVGATLPLITRIVMGFGMF
                     MKKFWIIVLLVIILFIYQFKKYLKTSVGRAHKDRVINKIPVLGKGINCMVATRFSRAL
                     YLFVSTGYPLVQGLDYIIDSVNNTMAEKILASAKDGITRGEGLAENLERYTYFDSVLV
                     QMIAIGEQTGELENISRQMAEFYEYESEIYLNRMASMIEPVLIIAVGIIVAILVVSIF
                     MPMLSIYDAM"
     gene            42651..44363
                     /locus_tag="ACGI5H_000375"
     CDS             42651..44363
                     /locus_tag="ACGI5H_000375"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437881.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PilN domain-containing protein"
                     /protein_id="HFG9696107.1"
                     /translation="MNKVYVSYYGDSISIVEGRYKHDKDKFYVKNFNVFSIEDIAQDF
                     SKEKYALLRYALENVKLKSRHVVFCLNTRDVILKPQKLPNMDKKDLDGFMKLEMDEMM
                     ALESDEYVFSYEVSSETPDNSDGDESSLNLIIGAIQKEEVNAIVEIMHEFDLVLDRID
                     TLSTAYLRMLKNLDYNDIMVTNISDNSTIINIYKKDTLFISDNIPIKITAKDMDMQLL
                     NVVEESKGLMNYYSSRNFGKVTDTILILGKRYSNKLIYETFSSAFSSYVSQGLTEIMD
                     ISDMITGDIDEDDINSIVELLGSMIEPKGKRDFENINFLPMDILRKQIKAKQMKNILK
                     IAPIVILILAIPYLCLIFSNNLANKELENVNGEIRNIESAYYQIGNIEKMIQSKSEEI
                     KVYDMLIGKKVKWENLLDDIDKNTPSKVELTSLSTTYQNLGTNNKADNSKSNKTTTDK
                     SSNNETKSSTKSDSNGDKTDNDLNEDKTTNVSEALTGNSETNSNNTDKDDKTPLYDKI
                     PNVINIEGNAKDSSYVGQFLYKLKGLYYFKDVKLHSIKSNAEDSNYTFSMTLYLKEGV
                     LTNE"
     gene            44356..45264
                     /gene="pilO"
                     /locus_tag="ACGI5H_000376"
     CDS             44356..45264
                     /gene="pilO"
                     /locus_tag="ACGI5H_000376"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425924.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0043107 - type IV pilus-dependent motility
                     [Evidence IEA];
                     GO_process: GO:0043683 - type IV pilus assembly [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type 4a pilus biogenesis protein PilO"
                     /protein_id="HFG9696108.1"
                     /translation="MNKDIFKKDIKDIFKMEVSLKGILIKVIILLAILSYGYFGLYPQ
                     YQKYIATKNSVKQATEKLNIYKEKTALMPKYEKQLEEVESELKEKSKNLLYDMQDGLF
                     LIGLDKKMKAYNIDLTSYDVGNVKEYEHFYGISTTISVRGDYRNVKKLMAYLEEQKNV
                     TQILDYTMTSYIEPEKEEEETTNNKDLIKNVNINKDTKIYWVEGENKWHLYKDCPLIK
                     EGEILKNDKLLDRSTNYLCNTCVLRAATEKEAKKEVVAPKAEGVVDATFKFIMYTKEN
                     TTMILDTDNPSSWRPGKYNPFKSSAK"
     gene            45291..45857
                     /locus_tag="ACGI5H_000377"
     CDS             45291..45857
                     /locus_tag="ACGI5H_000377"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437877.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prepilin-type N-terminal cleavage/methylation
                     domain-containing protein"
                     /protein_id="HFG9696109.1"
                     /translation="MSLYKNNEKGLTLLEVIIAVFILTIVLSISYKVFNGITSAVKKQ
                     QIITDAQVNINLINKYLNRDLENCKELTKTGSGNNYEYNIEMPDNVVKYEVSIETKKN
                     TEVYSVTRIQNNTIDTENEVREEIIYNQPLVQNNKEMKETPFKIEKQTGKSIYTVSIY
                     YNESVQESHKNSNLNNKTYTFDVMSRIG"
     gene            45894..46421
                     /locus_tag="ACGI5H_000378"
     CDS             45894..46421
                     /locus_tag="ACGI5H_000378"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425922.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prepilin-type N-terminal cleavage/methylation
                     domain-containing protein"
                     /protein_id="HFG9696110.1"
                     /translation="MSKKNSERGFSLIEVLVAMAIMGIVLFAFFNIINTNNKANTKND
                     TDITSLNYVQSEIENLREKIKSGEFDFDSLDKLEDGTVVYEKLIDKSKKVVYDKVLSE
                     GDVSLYDTPYEKITTIKDEDGNLIDKGNITNKIKTIVEDKSGQIYKIAVTGKSMNDYS
                     SKKEVKIVTEIFKDK"
     gene            46442..47980
                     /locus_tag="ACGI5H_000379"
     CDS             46442..47980
                     /locus_tag="ACGI5H_000379"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425921.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9696111.1"
                     /translation="MRKWNKFKSERGAALVLVLVVVALLSIVGLIFSNQIANRIKSTK
                     TTNEGIQAKYLAETCVENSIDKAYEKLYDELEKMDNEFKSENQEKSISRSKLRDISDE
                     DFNNQDEENIEAERLGYMNNINFYLNKASSDLEKASMELKKLYDLDMLDYRDIEYVDA
                     NIISHRDSILEICKNYTSGDISKINEYILKEDIDSTTLIEAKLVNNDILLKMFLEENK
                     IENEHLNSAFSHTYKALDNISLAMQNMIEYRHTFHIDEPKVEVSNGIPDSQQYYELIQ
                     NPIINSMEYIWNSKWDTLEKLLEILPNQTQGFNSLRVHLRNNVRKFEKLSDNISSGKK
                     NTAKNFLKYKELLYEISDQCNQLKSMSYEKIPVKYDNMALITTFDYIQNELLAEIKCR
                     LKELKPQEIDKTEGITIKIPFYKADYDMTKEGWPKLKENGSGAELSLMVTGDKDGIKE
                     VEVTDGKKNIIGLGVEENSNSKYKVDAIVNFNLNIDTNVVGNYDIKDKILINHDISSY
                     KKVN"
     gene            48080..49162
                     /locus_tag="ACGI5H_000380"
     CDS             48080..49162
                     /locus_tag="ACGI5H_000380"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437872.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0043107 - type IV pilus-dependent motility
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type IV pilus twitching motility protein PilT"
                     /protein_id="HFG9696112.1"
                     /translation="MYIYDLLEQGIRLNASDIHITVGTNPVARVKGGFVKLSEQILTS
                     EVTMQMAKDIAGESMFKVIEEHGEADFSASLKTGERFRVNAYRQKGNYAIAIRTITAE
                     IPTFEKLGLPESIKSFTEKHKGLVLVTGPTGSGKSTTLASMINIINEKQQKHIITLED
                     PIEYVHHHKQSLVNQREVGTDTESFHSALRAILRQDPDVILIGEMRDPETVSIALTAA
                     ETGHLVFSTLHTVGAAKTIDRIVDMFQPSQQQQIKTQLSTVCEGVVSQQLLPTADGKG
                     RIAAIELMFATPAIKNLIREGKTYQIPNMIQTGVKVGMKTMDQDLMELYKNGKITKDM
                     ALSRCTDQEFMTRMIGGVNYNGYYNR"
     gene            49143..49925
                     /locus_tag="ACGI5H_000381"
     CDS             49143..49925
                     /locus_tag="ACGI5H_000381"
                     /EC_number="3.4.23.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437871.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0004190 - aspartic-type endopeptidase
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="A24 family peptidase"
                     /protein_id="HFG9696113.1"
                     /translation="MDIIIVNLYVFMVGIVFGSFFNVCIFRIPEGISISRPPSHCMSC
                     NTRLKPIDLIPVLSYLMSGRKCRYCYEKISSRYAIVELITGLLFLTVFMLYGISTSTI
                     YYLVLVSLLIIITFIDIDHFIIPDKILVFGAIFSMIFNLLFKEIPVKDSILGVFICGG
                     SVWIIVLLIEFVIKKECMGGGDIKLFAMLGFYMGVKNGLLTALLSVYVGAVYGICVII
                     ISRIKGKEYNSVIPYGPFISIGALITILCGKQLLELYFSMVI"
     gene            50207..50677
                     /locus_tag="ACGI5H_000382"
     CDS             50207..50677
                     /locus_tag="ACGI5H_000382"
                     /EC_number="3.4.23.43"
                     /inference="COORDINATES: protein motif:HMM:NF013632.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0004190 - aspartic-type endopeptidase
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="prepilin peptidase"
                     /protein_id="HFG9696114.1"
                     /translation="MVLIPFLIIISIVDYYTIYVYDITIVSGIIVQGIIFLVFFNIVQ
                     FDYINHIFGLLIGFIIPYIIAKLTKGLGYGDVGLYSLCCFALGNNYGFYVIVLSFILA
                     FLFFIILYITKIFKDVDIRKQIPFTPFISLSTILIIFTEYNIFNFYYNLLYKFI"
     gene            50691..51251
                     /gene="pth"
                     /locus_tag="ACGI5H_000383"
     CDS             50691..51251
                     /gene="pth"
                     /locus_tag="ACGI5H_000383"
                     /EC_number="3.1.1.29"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421426.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004045 - aminoacyl-tRNA hydrolase
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="aminoacyl-tRNA hydrolase"
                     /protein_id="HFG9696115.1"
                     /translation="MYVVVGLGNPGKKYEKTRHNVGFDVIDILAKEYNISVTKIKHKA
                     LIGEGRVGTEKVLLVKPQTYMNLSGETLIDIYKYYKVDLSNIVVVYDDIDLEVGKIRI
                     RKKGSGGTHNGMKSITKCLGSNDFPRVRVGVSKPEAGQDLADFVLSRFRKEESDNINE
                     ALEKAADAIDSIIRENIDMSMNKYNG"
     gene            51268..54654
                     /gene="mfd"
                     /locus_tag="ACGI5H_000384"
     CDS             51268..54654
                     /gene="mfd"
                     /locus_tag="ACGI5H_000384"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894034.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003684 - damaged DNA binding [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="transcription-repair coupling factor"
                     /protein_id="HFG9696116.1"
                     /translation="MNDVFLYPLQNSKEYKDIINCIKNTKGSLLVNGLLPVQKPHISY
                     SIFNDLSRQMIFITSSDLEAKKVYEDLSFYMEDKVEYLGFQDIYFYHLDAKDRNEEAK
                     KLKVLLKLANKEKIILVTSIEAVLRKYIPKQVLLDSVSHYKVGDSLDLEKLTEKLVSL
                     GYERVSKIEGFGQFSIRGGIIDVFSLEYTNPIRMELFDDEIDSIRTFDVYSQKSIDKL
                     QQFSITPSREFIYPEKTTDALVKLKKETTKNTDEGTFQNIDYISSKTYFEGVENYIDY
                     IYPEENKSIFTYLADDAIVFINDITRLKERCENYINEFRENYKLNLERGLAIKNQGKL
                     LYHYTDLEYLVKDKSVVLNSLLPKSINNFSIKSIINFESREVPTFNGKVDLLVEELNR
                     LKYNGYKIILATNTLERANKLGKDLLDKGLETTISKDRDIEIKSSQVIIVPAHINSGF
                     QYKSIKFVVITDNEMIGVYKRASKTSNKKVKKGKKIESFLDLSVGDYVVHENSGVGRY
                     TGIEQITVNAIKKDYMKIVYQGGDNLYVPIDQMDKVQKYIGAEVEKVKLNKLGTNEWT
                     KAKAKVKKEIEDMTKDLIELYAKREKIQGYKFSKDTPWQAEFESLFPYQETEDQLKAI
                     EETKKDMESSKVMDRLVCGDVGYGKTEVAIRSIFKACMDQKQVAVLVPTTILAQQHYN
                     TFKERFENYPLRVEVLSRFKTPKQQKQIIEDAKKGLVDILIGTHRIISKDINLPNLGL
                     VVIDEEQRFGVKHKEALKKIKSTVDVLTLSATPIPRTLHMSLSGIRDMSVIEEPPQER
                     HPVITYVTESKESVIQDEIERELSRGGQVFFVYNRVEHIEEMASMIQKLVPDARVAVA
                     HGRMTSKSLENIILGFLNKDYDVLVCTTIIETGMDISNANTMIIYDADKMGLAQLYQL
                     RGRVGRSSRQGYAYLLYEKDKTLSEIAEKRLKAIREFTEFGSGFKIAMRDLEIRGAGN
                     ILGSQQHGHMAVIGYDLYVKMLNDAIKKVKGEPIVEEIDVEIDLSVNAYIPDNYIKDE
                     LIKIEMYKKIASIENKEDMLDIQEELEDRFSDIPKPVQTLLTIAYIKSLCKILKIEKI
                     RQLKDEILLVPITKYRTKQKIGYNIVTELEELLEKMCKVK"
     gene            54685..55680
                     /locus_tag="ACGI5H_000385"
     CDS             54685..55680
                     /locus_tag="ACGI5H_000385"
                     /EC_number="5.2.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421422.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase"
                     /protein_id="HFG9696117.1"
                     /translation="MKKVITLVIAMILVVSVTACSSSKGETVATVEGTKISSDEFKKT
                     IALYKDSMEQTYGKDIWDKEVEKGVKYKDKFKDLILDQLITTEVIYSQAKKDNLLPKK
                     EDVEKSFKELKDAMGKDEKYKEQLKKLGIDDEFLRDQQEKDLAMQNYQSNFAKKTKIS
                     DEEMKKYYDTHKDEFKKDEVEASHILLKTVDDNNKPLSDKEKAEAKKKAEEALKEVKS
                     GEDFAKVAKKYSQDTSASDGGKLGFFSRGQMVAEFEDAAFSMKKGEVSDLVETQYGYH
                     IIKVTDRINEQTSFEDAKETIKDQLLKNKYQEQIEKLTKEAKVEKDEKVINKITI"
     gene            55804..56343
                     /gene="spoVT"
                     /locus_tag="ACGI5H_000386"
     CDS             55804..56343
                     /gene="spoVT"
                     /locus_tag="ACGI5H_000386"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892063.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA];
                     GO_process: GO:0030436 - asexual sporulation [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="stage V sporulation protein T"
                     /protein_id="HFG9696118.1"
                     /translation="MKATGIVRRIDDLGRVVIPKEIRKTLRIREGDPLEIFTAKDGEV
                     ILKKYSPIGELNEFSQEYAETLAEVLGYGVLITDLDSIIAVSKLPKKDYKEKSISDEL
                     EAIISERTVKYSKDKNILPLFKEDQKEYTSQVIMPIISASGDCIGSIVVVSKDKDTIA
                     ESEEKSLKIAANFLGKQVQ"
     gene            56463..58076
                     /locus_tag="ACGI5H_000387"
     CDS             56463..58076
                     /locus_tag="ACGI5H_000387"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425909.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="oligosaccharide flippase family protein"
                     /protein_id="HFG9696119.1"
                     /translation="MNNNKNKDSFLKGALILGLAGVIVKIMGGFFRIPLGNMIGSEGM
                     GYYQAAYPVYTLFLTLATAGFPTAVAKLVSEKVAIGNFKGANKIFKVSHTVLFITGII
                     SFCILFFGADYIVTNVMKNPGALYSMKAIAPALLFVPAMSAYRGYFQGRQDMTKIAVS
                     QVAEQFFRVVLGLTLAYLLMKSLGQTFGAAGAISGATIGSIASMLYLVFAYMLGRKER
                     RAEIDASQRFKDERVSYIFKKLLTVAIPITIGASVMPLVNMIDNVIVIRRLMEAGFTY
                     KVANSMFGQLTGMAMATINLPAVITTAMSMSLVPAISKAYALGNKSKARKDTKSAVKV
                     TLLIVLPCAFGMASLAIPIMGLLFPHEPSSVGTILFTLTPCVLFLGLIQTLTGIIQGM
                     GKPIVPVIALCVGMLCKIVISYTLTGIPDINVLGSAFGTVTAYFVAAMINLLYVKKHM
                     NVNFSKKEFIIKPFITVMTMFIMVKLSYGALVGFLGNSISTIIAICVGGIVYVVVILG
                     IGGIKKEEILTMPKGDKLYKLLKKVKLIR"
     gene            58183..59631
                     /gene="mazG"
                     /locus_tag="ACGI5H_000388"
     CDS             58183..59631
                     /gene="mazG"
                     /locus_tag="ACGI5H_000388"
                     /EC_number="3.6.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894031.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside triphosphate pyrophosphohydrolase"
                     /protein_id="HFG9696120.1"
                     /translation="MGKISIVGLGPGDYSLISQGVLESLINSPKVFFRTEKHPIIDKL
                     KETIQYTSLDYFYEKEENFDNVYLKISEFIIEESAKGDLVYAVPGHPRVAEKTVSIIE
                     RLANEKHIAVEILPSMSFVDAMFNYLAIDPSEGFKLVDAFEIENSYIDLDTSMIITQV
                     YDKFIASNVKLKLMEHYDYNQEVCIVNGAGVKDLESKKFIKLCELDRNENFFDYLTSL
                     YIPKSSKKMYNTVHDLEIIVNTLRSPSGCEWDKKQTHQSLKNSVIEEAYELCNAIDNN
                     DIDEMVEELGDVLLQVIFHCQIGNEEGYFDLKEVVNGICKKLIHRHPHIFSGAKLDMS
                     KFEKTWEELKKEEKGESTITDGLRRIPKHLPALMKASKVQHKAALVGFDWDNVEDVFK
                     KIEEEYQELLDEHRVGNIKYIKEELGDLLFSIVNLARFLDIDSGEALNCTTEKFINRF
                     DFIEKSAMNLNKKLEDMTLEEMDEFWNQAKKQ"
     gene            59720..59998
                     /locus_tag="ACGI5H_000389"
     CDS             59720..59998
                     /locus_tag="ACGI5H_000389"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421415.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0030261 - chromosome condensation [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="HU family DNA-binding protein"
                     /protein_id="HFG9696121.1"
                     /translation="MNKAELVSKMAEKSGLTKKEAEAALNAFMSSVQDALVNNEKVQL
                     VGFGTFETRERAARQGRNPRDPEQVIDIPASKAPVFKAGKGLKDIING"
     gene            60070..60312
                     /locus_tag="ACGI5H_000390"
     CDS             60070..60312
                     /locus_tag="ACGI5H_000390"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421412.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-binding S4 domain-containing protein"
                     /protein_id="HFG9696122.1"
                     /translation="MRLDKFLKVSRIIKRRTVAKDACDKGIVTINGKVAKSSSEVNIG
                     DTLEIQFGEKKMKFKINEVKEHVLKNDAKEMYEILE"
     gene            60374..60628
                     /locus_tag="ACGI5H_000391"
     CDS             60374..60628
                     /locus_tag="ACGI5H_000391"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421411.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YabP/YqfC family sporulation protein"
                     /protein_id="HFG9696123.1"
                     /translation="MEQNITLKDRSKLVISGVEHIYSFNDKRVELKTSVGEMVIEGEN
                     LDMSKLSIDENIISIDGTINSMVYAKPKKPQESFLKKVFR"
     gene            60629..61162
                     /gene="yabQ"
                     /locus_tag="ACGI5H_000392"
     CDS             60629..61162
                     /gene="yabQ"
                     /locus_tag="ACGI5H_000392"
                     /inference="COORDINATES: protein motif:HMM:TIGR02893.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003674 - molecular_function [Evidence
                     IEA];
                     GO_process: GO:0034301 - endospore formation [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="spore cortex biosynthesis protein YabQ"
                     /protein_id="HFG9696124.1"
                     /translation="MIPFTQDVSIFYATIYGGILIGVLFDFYRGLRGNFKFINYFAII
                     FDVLFWFLATVIIFVTINLTEFFDLRYYHFVALFIGFILYYNTISKIVLSIINKIIRF
                     VRNSFKKVTHYIVSFLNNLYYVIIYSLHLLFDIIFYIPNIFIATRKSIKRKSNKKLKN
                     KKKSKPKKKKNKTKKRV"
     gene            61168..61452
                     /locus_tag="ACGI5H_000393"
     CDS             61168..61452
                     /locus_tag="ACGI5H_000393"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437861.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="septum formation initiator family protein"
                     /protein_id="HFG9696125.1"
                     /translation="MNLRKKFSGQIIVISLFLGISIFSMMTGFVFEYTKAKEYKKEIA
                     SLNKQLKKTEIQINSLKKDEKSYEGDLEDIARKRLNMVKPNETVYVDINR"
     gene            61565..62485
                     /locus_tag="ACGI5H_000394"
     CDS             61565..62485
                     /locus_tag="ACGI5H_000394"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Ppx/GppA family phosphatase"
                     /protein_id="HFG9696126.1"
                     /translation="MKVGAIDIGTNSMRLLIADYRDGNFINRKKFVNTTRIGYGVDSK
                     GYIKEDAIKRNIKALKEFSDKCNDEKCEKIYCMGTSALRDSKNGDYFVKLAKEETGID
                     VDIVTGIEESNLGFKGVLEGIQGDDTIIVIDIGGGSTEFIVGDSEGIIFNKSENVGAL
                     RMTERFLKHDIIEDEEFEAMSSFIYGEIDKTLNHIKDKGLKTLIGIGGTITSLSAMNQ
                     ELEIYSMEKIHNSKIHKKEIEEILQKLIKMTLSDKKNLKGLQEKRADIITAGVKILNI
                     IMEKLEIEEITVSEYDNLEGLICQKSKKMY"
     gene            62575..64947
                     /gene="spoIIE"
                     /locus_tag="ACGI5H_000395"
     CDS             62575..64947
                     /gene="spoIIE"
                     /locus_tag="ACGI5H_000395"
                     /EC_number="3.1.3.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425898.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0004722 - protein serine/threonine
                     phosphatase activity [Evidence IEA];
                     GO_process: GO:0030436 - asexual sporulation [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="stage II sporulation protein E"
                     /protein_id="HFG9696127.1"
                     /translation="MQRSVAVVKNKTVKPNVIKLISGYIDFTTAAFAVMGFLLSRSII
                     VDSVAPLGIAFFICASKIDKYKIPVFISTLLGILLSSNDFGNVAKYAVCLTIFMAMNK
                     KLKLSDSIAKVAFIGAIILLPISMGQAFFSNRYVYGLLIAGVEAIIMFISIYVFSYGI
                     GLMANVNNRMSVRTEEAISISLLLTFSIMGIGDISLFGISIRTILSTVLILLTSIVGG
                     ATMGASSGVIIGVASILNNMTSAVYMGIYSFSGLISGAFNKINKYFCILGYILSWTII
                     YLYTSGITSNMMQLRDILLGCLIVLVLPERLFNKIEKLIKSNVASNEIVYDYIMRSKN
                     LTNSRLNSIYKTYDDLADTFDKIREKDKVLDQRDIANVIDMIHNDECKSCSMRRMCWE
                     SRFNHTYTMIYNILEKIEEKGELSLNDIPKNFRKECMKPESIVKISNHYYKMFVLDYD
                     WSVKFSESRKLIANQIRSISKSIKSLSQDLEGDIMLDIEKEKNIYEQLERYDITVDKV
                     SYLTKSNSEFEISIEKKTCHDGCMCEDKIVNIISDLVGENMSVRKIGCHCLGGKCKAT
                     FVKSQKYKAVTEVSAMSRDGHILCGDNYTYMEINDGKYMMAISDGMGKGKKAYEESSA
                     TIDILEKMIDAKIKDEIVIDTINNMLLLKSSEEMFSTLDLGILDLKRGCLETIKMGAC
                     STYIKREDGEVDLISSSSLPVGILSDVKIDRKNVKVKEGDYVIMVSDGIVDAGRNNNL
                     GDNWLIYFLKNIETTNPKEISNLILDRALELQALQIEDDMTVLVTKICTK"
     gene            65298..67190
                     /gene="pepF"
                     /locus_tag="ACGI5H_000396"
     CDS             65298..67190
                     /gene="pepF"
                     /locus_tag="ACGI5H_000396"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898717.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004222 - metalloendopeptidase activity
                     [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="oligoendopeptidase F"
                     /protein_id="HFG9696128.1"
                     /translation="MNRKLCKAIIPLFISIFCMLIISIKADQGYQKNNDRAITVMNNN
                     DTEDDAEKKQEIDYEKTCWNLQSLFKSDDQWKKELKSFDKDTKELKNYIGKVTKSPTH
                     LSFALNIKEKLDIRLNKLSAYVKLKQDTNKNSYKYLDMNDSMSKSYGNYMGICSDLEL
                     EILKLSNKDYKKIISNKNINRKYGAYLRDIRRNKVHYLDDKSEDILSKVSSISSLPSQ
                     VYELFRNMDRKTNLTPAQYASELESSDRENRKKAYQDELITYNDNINTIAGLITGQVK
                     KNIFYSQERGYESSLEMYLESDNVDEKVYNNLIRTVNSNMDSLHKYIDLRKKVLKLDK
                     VHSYDMFVPMVKAVDNNINYEKAQSIVYSALSPLGKEYNDVVYKAFNEKWIDVYSHEN
                     KVSGGYCLSVYENHPYILLNYNNSLGSVSTLSHELGHAVYEYLSSKNQNYFNSNPSIF
                     THEVASTTNEALLYEMLIKEAKGNDEKAYYITQYLDLIKDTLYTQTMYAEFEKTIHEL
                     VEKGKSVNALVLNDVWGQLLKKYYGQSYELDQLSKVGWARIPHFYNSFYVYKYATGCS
                     AGVSFAQDILKNGSDNYMSFLKKGSSDYPINLLKSSGINLTNTKPIENTIKKFDSLVA
                     ELEKLL"
     gene            67304..68269
                     /gene="galU"
                     /locus_tag="ACGI5H_000397"
     CDS             67304..68269
                     /gene="galU"
                     /locus_tag="ACGI5H_000397"
                     /EC_number="2.7.7.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892053.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003983 - UTP:glucose-1-phosphate
                     uridylyltransferase activity [Evidence IEA];
                     GO_process: GO:0006011 - UDP-glucose metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="UTP--glucose-1-phosphate uridylyltransferase
                     GalU"
                     /protein_id="HFG9696129.1"
                     /translation="MQVKVKKAVIPAAGLGTRFLPATKAQPKEMLPIVDKPTLQYIIE
                     EAVASGIEEILIITGRNKKSIEDHFDKSVELELDLEKKGKKELLEVVQNISNMINIHY
                     IRQKEPKGLGDAIYCARHFIGDEPFAVMLGDDIVDNDVPCLKQLTDAYEEYRTTILGV
                     QKVNQEDTNKYGIIEAKNIEGRVYKVKDMVEKPESGKAPSNIAILGRYIITPEIFDIL
                     KDLPPGKGGEVQLTDALKILSKKEAMYAYNFEGKRYDVGDKLGFLEATVDFALKKEDL
                     KEDFIKYLKHVCSEFDKNNNVLYNNTDEKIDLIEVNEARELEIQK"
     gene            68769..70373
                     /gene="rho"
                     /locus_tag="ACGI5H_000398"
     CDS             68769..70373
                     /gene="rho"
                     /locus_tag="ACGI5H_000398"
                     /EC_number="3.6.4.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425893.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0008186 - ATP-dependent activity, acting
                     on RNA [Evidence IEA];
                     GO_process: GO:0006353 - DNA-templated transcription
                     termination [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="transcription termination factor Rho"
                     /protein_id="HFG9696130.1"
                     /translation="MRRIFLILDDKVLEGLGSKTLVELREIAKELKIKSITTYKKNEL
                     IEIINSKSKNEEKVNEETKEKNEDIKEDIKNRKENIERESIEKEVEYKSPTKSYNKKE
                     IDTQNISQNQEHRNQRNDYNKTTSVNDSNKSSNISNRMVRNNNKNYYMPKQVDESKIV
                     DEFNTSKEDEVVGVLEILPDGFGFLRGSNYLSTEGDVYVSPSQIRRFNMKTGDKIKGI
                     TRHPKSGEKFRALLYVQKINDENPDTAIQRNAFETLTPIFPEERLTLETNRNEIATRI
                     IDLISPIGKGQRGLIVAPPKAGKTVLLKSVANSIAKNHPNVELIVLLIDERPEEVTDM
                     KESIEGDVIYSTFDQVSSHHVKVAEMVLNRAQRLVEHGKDVVILLDSITRLARAYNLT
                     ISPTGRTLSGGIDPGALHGPKKFFGAARNIRQGGSLTILGTALVETGSRMDDVIFEEF
                     KGTGNMELHLDRKLAEKRIFPAIDIYKSGTRRDDLLLDDEEKTALWRLRREMSNNSVM
                     EITDKVIELIKRTKDNKEFVKSIKNL"
     gene            70526..70726
                     /gene="rpmE"
                     /locus_tag="ACGI5H_000399"
     CDS             70526..70726
                     /gene="rpmE"
                     /locus_tag="ACGI5H_000399"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018591942.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L31"
                     /protein_id="HFG9696131.1"
                     /translation="MQKEIQPKYNPVEVRCACGNTFVAGSTKDEIKVEICSECHPFYT
                     GKQKNIEKGGRIDKFKKRFKMD"
     gene            70871..71764
                     /locus_tag="ACGI5H_000400"
     CDS             70871..71764
                     /locus_tag="ACGI5H_000400"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425891.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1385 domain-containing protein"
                     /protein_id="HFG9696132.1"
                     /translation="MAKQAVGGQAVIEGVMMQSKDKRAVAVRKSDGEIALKEDRIKSW
                     VRDKNIDKIPFVRGSFVMIDTMIQGIKSLNFSSEFFMEEAEEDKFDLFIKKIFKDKAN
                     DIIIIFSLVIAMLLSAGLFIFIPTLVGGAFSKVMPNDFMLNLIEGIIRIAILFAYIVL
                     ISRSKDIERVFQYHGAEHKSIYCYENDLELTVENARKFKRLHPRCGTNFLFIVMAVSI
                     ILFAFFGWPNPILRIFMRIICVPIVAGLSYEVIRVLGKYDNGFTKIIAYPGMMLQYFT
                     TKEPDDEQLEVALEALKAVVD"
     gene            71782..72630
                     /gene="prmC"
                     /locus_tag="ACGI5H_000401"
     CDS             71782..72630
                     /gene="prmC"
                     /locus_tag="ACGI5H_000401"
                     /EC_number="2.1.1.297"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437849.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008757 - S-adenosylmethionine-dependent
                     methyltransferase activity [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA];
                     GO_process: GO:0018364 - peptidyl-glutamine methylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor N(5)-glutamine
                     methyltransferase"
                     /protein_id="HFG9696133.1"
                     /translation="MTIKDIIIKYSDKLKDISDTPRLDTELLLQKTLGVDRLYIHLNL
                     NKELTEEQKTKFMGFAEERLNGRPIAYIVENREFMGLDFFVKEGVLIPRPDTETLVEE
                     IIEICREKKDVSILDIGTGSGAITISLAKYIENSKIMSFDISETALEIAKKNAIINEV
                     GEKIKYINSDLFTAISDSNIKFDIIVSNPPYIKKQDIETLHKQVKDYEPYNALEGGED
                     GLDFYRRITEQGKKYLNKCGILAYEVGHNQAEDVINIMKSNGYKKIYTKKDIQGIDRV
                     VIGYNI"
     gene            72674..73738
                     /gene="prfA"
                     /locus_tag="ACGI5H_000402"
     CDS             72674..73738
                     /gene="prfA"
                     /locus_tag="ACGI5H_000402"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421389.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003747 - translation release factor
                     activity [Evidence IEA];
                     GO_process: GO:0006415 - translational termination
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor 1"
                     /protein_id="HFG9696134.1"
                     /translation="MLKKLEVLEDTYKDLSEKIGDPDVINDQKVWQKYIKEHADLEPI
                     VMKYREYKSVLDSIKESKEILQEESDEELRELAKMELAEMEEKVAPLEEEIKILLLPK
                     DPNDDKNVIVEIRGGAGGDEAALFAGDLFRMYSRYAERRRWKIELLSASDTGVGGYKE
                     VSFMIKGKGAYSRLKYESGVHRVQRIPSTESGGRIHTSTSTVAVLPEVEDVEVEINPN
                     DLRIDVFRSSGNGGQSVNTTDSAVRVTHIPTGEVVSCQDGKSQLKNKEQALKILKARL
                     YDKALAEQHKDIAAERKSQVGTGDRSERIRTYNFPQGRISDHRINLTLYKLDAFLDGD
                     IDEMIDALITVDQTEKMTAI"
     gene            73867..74547
                     /locus_tag="ACGI5H_000403"
     CDS             73867..74547
                     /locus_tag="ACGI5H_000403"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425887.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0046873 - metal ion transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0030001 - metal ion transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ZIP family metal transporter"
                     /protein_id="HFG9696135.1"
                     /translation="MILKVTIIGLLAGVIGTGLGGVISAIFKREVDKYLSFFMGLSGG
                     IMLAVVVFDLMKESMDKMGIINTVIFTFVGALITMYIKTKLDVSGNMASGYLIFISIL
                     LHNLPEGLAIGSSFMSTESLGITLAIVIGLHNIPEGLAMALGLVCNKMKLSKVILFTV
                     IAGLPMGLGSFLGVYFGGVFTSLIGVFLATAGGTMMYVVLEEIFPHSKSVYCIIGFLL
                     GTMIVNYI"
     gene            74576..75616
                     /locus_tag="ACGI5H_000404"
     CDS             74576..75616
                     /locus_tag="ACGI5H_000404"
                     /EC_number="2.7.7.87"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009906516.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003725 - double-stranded RNA binding
                     [Evidence IEA];
                     GO_function: GO:0061710 - L-threonylcarbamoyladenylate
                     synthase [Evidence IEA];
                     GO_process: GO:0006400 - tRNA modification [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="L-threonylcarbamoyladenylate synthase"
                     /protein_id="HFG9696136.1"
                     /translation="MKTIISNIDINNIDYEEIKIQAKLLREGKTVIFPTETVYGLGAN
                     ALDENAVKKIYEAKGRPSDNPLIVHIYEKEEVYDLAKDISDKAKLVIEKLWPGPITII
                     LNKKDIIPYKTSGGLDTVAIRMPSNVIARAIIKEAGIPIAAPSANISGRPSPTKAKHV
                     YEEMNGRVDGIVLGGDSNFGLESTVLDLTEETPMILRPGSITKEVLEELLGEVKLDPS
                     LSKKEDNQKAKAPGMKYKHYSPNADVYIISGKRENVATKINDMIKSNRDKGLKTGVMC
                     ISRNREFYDGEVIDLGNSLEEVASNLFDALIEMDKKGVDVIYSEEFPKTGVGQAIMNR
                     LLKSAGYKVIKA"
     gene            75633..76082
                     /locus_tag="ACGI5H_000405"
     CDS             75633..76082
                     /locus_tag="ACGI5H_000405"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437844.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="low molecular weight protein arginine
                     phosphatase"
                     /protein_id="HFG9696137.1"
                     /translation="MNILIVCTGNTCRSPMAEAILRKAIKESGRSIEEYSISSAGIST
                     ANGMGASENSIEVLKEIGIDLSNHRSKVITKKLIDESDIILTMTKSHKEILVQAVPKC
                     KEKVYTFKGFANKNEEDISDPFGGNLDIYRSTMREIMYSVNEIVKKI"
     gene            76099..76551
                     /gene="rpiB"
                     /locus_tag="ACGI5H_000406"
     CDS             76099..76551
                     /gene="rpiB"
                     /locus_tag="ACGI5H_000406"
                     /EC_number="5.3.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421381.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004751 - ribose-5-phosphate isomerase
                     activity [Evidence IEA];
                     GO_process: GO:0009052 - pentose-phosphate shunt,
                     non-oxidative branch [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribose 5-phosphate isomerase B"
                     /protein_id="HFG9696138.1"
                     /translation="MKIGLGCDHGGYNLKKEIISYLESKGIECVDYGTNNATDSVDYP
                     VYGEIVANSVINKEVDYGILCCGTGIGISLAANKVPGIRCAVVSDVFSAKMSKAHNDA
                     NMLSLGERVLGKGLALEIVEAWINTDFEGDRHARRVNMIKSIEEKHNK"
     gene            76587..77216
                     /gene="upp"
                     /locus_tag="ACGI5H_000407"
     CDS             76587..77216
                     /gene="upp"
                     /locus_tag="ACGI5H_000407"
                     /EC_number="2.4.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011971477.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004845 - uracil phosphoribosyltransferase
                     activity [Evidence IEA];
                     GO_process: GO:0009116 - nucleoside metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="uracil phosphoribosyltransferase"
                     /protein_id="HFG9696139.1"
                     /translation="MSKVVETNHPLIQHKLTLMRDKNTGSKDFRELLTEIAMLMGYEI
                     TKDIPLKDVEIETPIQKTSSKVVAGKKLAIIPILRAGLGMVDGLVSLMPAAKVGHVGL
                     YRDPETLKPVEYYCKLPQDIGERDIIVVDPMLATGGSAVAAIDLLKSKGAKSIKLANL
                     VAAPEGIAEVQKYHDDVDIYVASVDERLNEHGYIIPGLGDAGDRLFGTK"
     gene            77511..78326
                     /gene="yqeB"
                     /locus_tag="ACGI5H_000408"
     CDS             77511..78326
                     /gene="yqeB"
                     /locus_tag="ACGI5H_000408"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898711.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="selenium-dependent molybdenum cofactor
                     biosynthesis protein YqeB"
                     /protein_id="HFG9696140.1"
                     /translation="MKNCIVVRGAGDLATAVIHKLHNSGFKVVALEIEEPLAIRRQIS
                     FCEAVYEKKVTVEGVECIFCNTEKEIEEVLSQHKVALIIDPKGEKLSKLNPIVLVDGI
                     LAKKNLGTTKDMAPLTIALGPGFCAGEDVDVVIETMRGHNLGRIITNGRAEKNTGVPG
                     AIKGFSKERVMHSQYDGIMENVCKIGDIVEKGDLLCYINNYEKKHEVRATISGVLRGL
                     LKDGAKVNKNLKILDIDPRKEEVKNAFTISDKARCIAGGVLEAILNNGIYPQN"
     gene            78552..78989
                     /locus_tag="ACGI5H_000409"
     CDS             78552..78989
                     /locus_tag="ACGI5H_000409"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421374.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytidine/deoxycytidylate deaminase family
                     protein"
                     /protein_id="HFG9696141.1"
                     /translation="MRPSWDEYFMEIAEVVKKRSTCIRRQVGAVIVRDKQILTTGYNG
                     SPRNLEHCENIGCKRQELNIPSGERHELCRALHAEQNAIIQAAHNGISVDGATLYVTT
                     RPCVLCAKMCINAGILKIVYEGDYPDDMSTELLKEAGIELIKF"
     gene            79174..79401
                     /locus_tag="ACGI5H_000410"
     CDS             79174..79401
                     /locus_tag="ACGI5H_000410"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0045263 - proton-transporting ATP
                     synthase complex, coupling factor F(o) [Evidence IEA];
                     GO_process: GO:1902600 - proton transmembrane transport
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="AtpZ/AtpI family protein"
                     /protein_id="HFG9696142.1"
                     /translation="MSKRNTHTEIAKLFSLISQIGLMIVISILGCTFLGKFLDSKLNT
                     TPVLTIIFLLLGVGGAFSGVYKTLIVYTRRK"
     gene            79406..79792
                     /locus_tag="ACGI5H_000411"
     CDS             79406..79792
                     /locus_tag="ACGI5H_000411"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425864.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP synthase subunit I"
                     /protein_id="HFG9696143.1"
                     /translation="MDIKLLNQVRSVTKGIVIFDVVLIVLMLITSTLSKPVLLGLIFG
                     SIIAMLNFRLLAISLEKSVTFPAGKAQAYASAQYAVRLFIMAVVLIASATVPHLNIIG
                     TALGLLSTKFVILSKNFINKLKRKEA"
     gene            79795..80499
                     /gene="atpB"
                     /locus_tag="ACGI5H_000412"
     CDS             79795..80499
                     /gene="atpB"
                     /locus_tag="ACGI5H_000412"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0000276 - mitochondrial
                     proton-transporting ATP synthase complex, coupling factor
                     F(o) [Evidence IEA];
                     GO_component: GO:0045263 - proton-transporting ATP
                     synthase complex, coupling factor F(o) [Evidence IEA];
                     GO_component: GO:0045264 - plasma membrane
                     proton-transporting ATP synthase complex, coupling factor
                     F(o) [Evidence IEA];
                     GO_function: GO:0046933 - proton-transporting ATP synthase
                     activity, rotational mechanism [Evidence IEA];
                     GO_process: GO:0015986 - proton motive force-driven ATP
                     synthesis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit A"
                     /protein_id="HFG9696144.1"
                     /translation="MNQAHYYLIGNFKISETILVSWGIMAFLAIASYFLTRNLKKVPT
                     SKVQIFLEFAVGGLAKMVTDVMGKNTVKRMPYMIPYIGSLFLFFACSNLSPLLGLRSP
                     TTDLDTTAAWAMITFFMIYFAGVKFKGLSYFKELAQPLAIMLPINIIGELARPISLSF
                     RPFGNILGGTIIMGLFYQLLGFISSLIPGLSIPIGEILIPVPLHLYFDLFAGLLQAYI
                     FIMLTMVFISSAGELD"
     gene            80568..80828
                     /gene="atpE"
                     /locus_tag="ACGI5H_000413"
     CDS             80568..80828
                     /gene="atpE"
                     /locus_tag="ACGI5H_000413"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421370.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0045263 - proton-transporting ATP
                     synthase complex, coupling factor F(o) [Evidence IEA];
                     GO_function: GO:0015078 - proton transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0015986 - proton motive force-driven ATP
                     synthesis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP synthase F0 subunit C"
                     /protein_id="HFG9696145.1"
                     /translation="METAIVAAASAIGAGIAVATGIGAGIGQGIAAAKAAEAVGNQPE
                     AKGDITSTLLLGVAIAESSAIYGLVISIILLFVNPFFKYLGM"
     gene            80951..81448
                     /gene="atpF"
                     /locus_tag="ACGI5H_000414"
     CDS             80951..81448
                     /gene="atpF"
                     /locus_tag="ACGI5H_000414"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009906514.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0045263 - proton-transporting ATP
                     synthase complex, coupling factor F(o) [Evidence IEA];
                     GO_function: GO:0015078 - proton transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0015986 - proton motive force-driven ATP
                     synthesis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit B"
                     /protein_id="HFG9696146.1"
                     /translation="MEKALVGITWEFVFQIVNTFIIFLLLRKLLFKPVLNIIESREND
                     IKSDLAEGEKAKNEGLALKKEYESKINFAKDEGQEIIKQATIRAEQKSDDIVNTAKKD
                     ALDIKEKANKDIEQERQKVINEIKNDISNIALLAASKVIEKDLDKSKHEELIENFIKE
                     VGEAK"
     gene            81445..81990
                     /locus_tag="ACGI5H_000415"
     CDS             81445..81990
                     /locus_tag="ACGI5H_000415"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425856.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0046933 - proton-transporting ATP synthase
                     activity, rotational mechanism [Evidence IEA];
                     GO_process: GO:0015986 - proton motive force-driven ATP
                     synthesis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit delta"
                     /protein_id="HFG9696147.1"
                     /translation="MINVIANRYAEALFQLGEEENSTDVLFKELEKVVDMMTKVSKDF
                     YKVLKSPLVSKSEKKNLVEIIFSKEVSSNIKNFLKVLVDKDRISYLEDIELAYKELLN
                     KKNNVIDGVAISAIPMSETDIKELEVKLSNKYNKNVTIENVVDKTILGGVLVRIGNEQ
                     IDGTVKTRLDKMKEKLSEVIS"
     gene            82007..83509
                     /gene="atpA"
                     /locus_tag="ACGI5H_000416"
     CDS             82007..83509
                     /gene="atpA"
                     /locus_tag="ACGI5H_000416"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421367.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0045261 - proton-transporting ATP
                     synthase complex, catalytic core F(1) [Evidence IEA];
                     GO_component: GO:0045262 - plasma membrane
                     proton-transporting ATP synthase complex, catalytic core
                     F(1) [Evidence IEA];
                     GO_function: GO:0046933 - proton-transporting ATP synthase
                     activity, rotational mechanism [Evidence IEA];
                     GO_process: GO:0015986 - proton motive force-driven ATP
                     synthesis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit alpha"
                     /protein_id="HFG9696148.1"
                     /translation="MNLKPEEISSIIKQQIKNYENKVELTDTGSVLTVGDGIASVYGL
                     EKAMSGELLEFPGEIYGMALNLEEEVVGAVILGDDSEIKEGDIVKRTGRIVEVPVGEA
                     LIGRVVNSLGQPIDGKGPIAYTKTRPVESEAPGIIDRRSVYEPLQTGIKSIDSMIPIG
                     RGQRELIIGDRQTGKTSIVIDTILNQKGKDVICIYVAIGQKRSTIAQLVSSLEKGGAL
                     DYTIVVSATASESAPLQYIAPYAGAAMGEEFMYNGKHVLIVYDDLSKQAVAYREMSLL
                     LRRPPGREAYPGDVFYLHSRLLERAAKLSDELGGGSMTALPIIETQAGDVSAYIPTNV
                     ISITDGQIYLQPELFYSGVRPAVDPGISVSRVGGSAQIKAMKKVAGTLKLAYSQYREL
                     AAFSQFGSDLDEDTKKRLAQGERIVEILKQGEHQPIKVENQVMIIYAVINNHLEDIPI
                     DNIARFESELYAFVDNNYPEISRKILGGEDFTHDLTDAINEFKEKFVVEV"
     gene            83537..84415
                     /gene="atpG"
                     /locus_tag="ACGI5H_000417"
     CDS             83537..84415
                     /gene="atpG"
                     /locus_tag="ACGI5H_000417"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421366.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0045261 - proton-transporting ATP
                     synthase complex, catalytic core F(1) [Evidence IEA];
                     GO_component: GO:0045262 - plasma membrane
                     proton-transporting ATP synthase complex, catalytic core
                     F(1) [Evidence IEA];
                     GO_function: GO:0046933 - proton-transporting ATP synthase
                     activity, rotational mechanism [Evidence IEA];
                     GO_process: GO:0015986 - proton motive force-driven ATP
                     synthesis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP synthase F1 subunit gamma"
                     /protein_id="HFG9696149.1"
                     /translation="MAGAGIKAIKTRMGTVESTKQITKAMELVASSKLRKAKEKAEDS
                     REYFNTLYNTVKDIAQTTRGIRNEFLKEREVKNKCYVVVAGDRGLAGGYNSNVLKESV
                     SHMKGKKETVITVGKKAHEFFSKRNYNIAKDINSVEACGYEDATEISQTIIDLYKKGE
                     VDEVYIAYTKFKSALSQEVEILKLLPLVFEKDTDEQGMAVKEEKQNRSKVQYIPSAEA
                     VLSYIVPQFISGTVYGGILESFASEQGARRTAMESATDNANEMLSNLELSYNRARQSA
                     VTQEITEIVGGVEALK"
     gene            84428..85822
                     /gene="atpD"
                     /locus_tag="ACGI5H_000418"
     CDS             84428..85822
                     /gene="atpD"
                     /locus_tag="ACGI5H_000418"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425850.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0045261 - proton-transporting ATP
                     synthase complex, catalytic core F(1) [Evidence IEA];
                     GO_component: GO:0045262 - plasma membrane
                     proton-transporting ATP synthase complex, catalytic core
                     F(1) [Evidence IEA];
                     GO_function: GO:0046933 - proton-transporting ATP synthase
                     activity, rotational mechanism [Evidence IEA];
                     GO_process: GO:0015986 - proton motive force-driven ATP
                     synthesis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit beta"
                     /protein_id="HFG9696150.1"
                     /translation="MANVGKVVQIVGAVLDVKFDSEQSLPNLLNALVIKLGDKEIVAE
                     VAQHIGDDTVRCIAMSATDGLVRGMEVVDTGGPISVPVGDETLGRIFNVLGKPVDGKP
                     APKSAPKLPIHRPAPAYDELETTAEILETGIKVVDLLAPYLKGGKIGLFGGAGVGKTV
                     LIQELINNIAKQHGGISVFSGVGERTREGNDLYGEMSESGVINKTALVFGQMNEPPGA
                     RMRVALTGLTMAEHFRDEQGQDVLLFVDNIFRFTQAGSEVSALLGRMPSAVGYQPTLA
                     TEMGALQERITSTKKGSITSVQAVYVPADDLTDPAPATTFSHLDAKTVLSRQISSLGI
                     YPAVDPLESTSRILDPSIVGKEHYEVARGVQSILQRYKELQDIIAILGMDELSDEDKL
                     IVARARKIQRFLSQSFTVAEQFTGNPGQYVPVKETVRGFKEILEGKHDDLPESAFLFV
                     GTIEDAVRKAKGSM"
     gene            85825..86085
                     /gene="atpC"
                     /locus_tag="ACGI5H_000419"
     CDS             85825..86085
                     /gene="atpC"
                     /locus_tag="ACGI5H_000419"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421364.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0045261 - proton-transporting ATP
                     synthase complex, catalytic core F(1) [Evidence IEA];
                     GO_component: GO:0045262 - plasma membrane
                     proton-transporting ATP synthase complex, catalytic core
                     F(1) [Evidence IEA];
                     GO_function: GO:0046933 - proton-transporting ATP synthase
                     activity, rotational mechanism [Evidence IEA];
                     GO_process: GO:0015986 - proton motive force-driven ATP
                     synthesis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP synthase F1 subunit epsilon"
                     /protein_id="HFG9696151.1"
                     /translation="MASEFSLKVVTPSNTFYDGDVEMIVVRTTKGDKGVLKGHIPFVS
                     GIPVGTLKIKKEGSFKEAKIAEGFINVTQDKTVILTESAEWI"
BASE COUNT        34778 a         9323 c        15858 g        26375 t
ORIGIN      
        1 tattaaaaac ttaatagaaa tattaagcat aaagattatg tggttacaat agcagagagg
       61 atacacctgt tcccattccg aacacagaag ttaagctctc tagcgctgat ggtacttggt
      121 gggaaactgc ctgggagagt aggacgtagc cacgtaattt tttttatttt ttgtcaaaaa
      181 aaacaaaaaa tacgtatttc ttttttcatt tcgggaaaac taaacacagg aattatggac
      241 tttataaaaa tttaattctt gaggagtgat ataagtgaaa aaagttgctt taattttagc
      301 tataataggt gcgcttaact ggggtgcaat tggtattcta ggtacagact taataggtag
      361 tatctttggt ggaacatatg aaatggtaag tagaataata tacttcattg taggtttagc
      421 tggattatac ttaataccaa gtttaatgtc tgatgataga gaataattta tgcttttatg
      481 ttaaatacct cattctaaat gtttagaatg aggtatttaa ttttataaaa atattaattt
      541 gtttcttttt taatggtaaa atagataaga attgaagttt taaaaagaag tattatgtaa
      601 aaaaggagta ctattaatat atgtttatta ttaatgaatt aaataagatt gtaaatgaag
      661 aagtaatatc ttttcatatg cctggtcata aaaagggaca ggtttataaa aagttaggat
      721 ataaagatat actaaaaaat ttgtataaaa tggatacaac tgagatatta ggaacagata
      781 atttacactt tccggaagga attataaaaa attcacaaaa aaaagcatca agagtattta
      841 aaagtgatta tacttgctat ttagtaaatg gtagtagctg tggaatacaa tctgcaataa
      901 tgtcagtatg tagtcctaaa agtaaaataa taacaaatag agactgtcat cagtctgtta
      961 taaatggatg tattttagga gatatagata tagagtatgt gccttgtgag ataagtgaag
     1021 agacaaatgt cttaaaaggg atatctataa gtaatgtgat tgatataata gataaaaact
     1081 tggatgcaaa agcagtactg cttacttatc ctacatatta tggaatgaca tatgatttag
     1141 aatacatatg taattatgca catagcaaaa agatggtagt gatagtagat gaagcacatg
     1201 gtgcgcattt agggcttagc gagaggcttc ctaaaacagc tcttgagcaa ggcgcagata
     1261 tagttgtaca gagtacacat aaaactcttc cagcatttac acaatcgtca atgatacata
     1321 tacagggaga ccgagttgat atagataaaa tattgaacat gttaagaatt acagaatctt
     1381 caagcccttc atatttatta ttatcttctc tggaattagc agtagatata tatgaaaata
     1441 aaggaaaaga attaatggaa gagcttttaa ataatattat aactttcaaa aataaagttg
     1501 attcaaatat taatatatac gacacaaatg ataaaacaaa aatatttata tcatctaaaa
     1561 atatgggttt aacaggttat gaactagaaa atattttaag aaacaaatat aacatacaag
     1621 tggagttatc taattattat ggagttcttt taatatgtac aataggaaat actgttgagg
     1681 atttctctag tttagaaaca gcattaaaca atattgtaaa ggaagacttt aaatttgaaa
     1741 agttagaaaa taaaaaatac cctgttgtta ttccaaagaa aatattaaca cctagagaag
     1801 cattttataa aactaaaaaa agtgttaaaa tatatgacag cataggtaaa gtttgtggtg
     1861 aatgtatagt tccataccca cctggaataa gtgtaatatc tcctggtgaa gtaataagta
     1921 aagaaataat agactatcta atgttttgtc attctaaagg catgattgtg agtggattga
     1981 aagatgtaga tttaaatttt atacaaataa tagatttaga agacatttaa aaattatgat
     2041 ataaaagtag atagaagtag atagtttaaa attgtgaaga gaaataaata gactgcttat
     2101 atagagctat ctaataaaag tactaaaaaa gtaaaaagtg tttgtatgga ggatatgaaa
     2161 atgaaaggta agttaataat tatagagagt ggttcagatg caagtggaaa ggctactcag
     2221 acagaaatat tatatgaaag attaaaaaaa gaaggctata tgattaaaaa ggtagaatat
     2281 ccaaattatg aatctccatc atctgccttg gtgaaaatgt acctaaaagg agactttggt
     2341 aaaaatgcat cagatgtaga cccatatata gcatcaactt tttttacagc tgataggtat
     2401 gcatcattta aaaccgattg ggaggagttt tacaatgaag gtggaataat tatcgcagat
     2461 agatatacaa cctctaatat ggtacatcag gcctctaaaa tggatatttg tgatagagaa
     2521 gagtatttaa attggttagc tgattatgaa tttaatttat ttaagatacc acaacctgat
     2581 tgtgttatat ttttagatgt gcctattgaa tttagtaaaa agcttatgga gaatagaaaa
     2641 aataaaatta caggggaaga aaaaaaggat attcatgaaa gtgacataga gtatttagag
     2701 aaatcttaca acaatgcttt atatatagca gataaatatg attggaaaaa aataaattgt
     2761 gttttagata acaaattaag aagtattgaa agtatacata atgaaattta taaaatagtt
     2821 cttgattcaa taaaacctat ggagagataa atatgtattt tgaaaatatt atagggcaag
     2881 attttgcaaa gaaatattta acaaattcta taaagaaaaa taaacttaat aatgcgtata
     2941 tgtttgaagg aatggatgga ataggaaaaa agaaatttgc agatgaatta tcaaaactat
     3001 tacttgatta tgaaaatctc gaaaatagtc cagactatgt actcataaaa ccagatggaa
     3061 atagtataaa aatagctcaa atcagaaatt tacaatcaga tatagtaata agacctcata
     3121 aagactataa aatatatata atcaataatg ctgaaaaaat gactgtggaa gctcaaaatg
     3181 cacttttaaa gacgctagag gaacctccaa actatgctat aataatctta gtcacaaaca
     3241 acaaggaatc tttattagaa actataaaat ctagatgtga tataataaag ttctcaccta
     3301 taccaattga agacttaaaa cgttatttga taaatacagg tatagaagaa gaaagagctc
     3361 aattattggc tattttttcg agaggaagta ttgagaatgc tctaaatcta tctcagtctt
     3421 ctgagttttc aatgatgaga gaagatatac aacagtatat tcagataatg ttagataaaa
     3481 acatagtgga gattttaaat ataccaaata atatggaaaa atatagaggt aagattatag
     3541 ctttattaga tatgatgata aactattttc gagatatcat cctattaaaa gaaaatgtaa
     3601 acaagaacat gttaataaat gtagataagc tagttttcat tcaaaatatg agtggaaaaa
     3661 ttagttattc tcaattgtcc aagattattg atataataga agatgcaaag agtaaaataa
     3721 aaagcaattg caatttcaat ataagcatac aagttatgtc tttaaatata tacgaggtga
     3781 ttaaatgata aagatagtag gtataaggtt taaaagtgct gggaaaatat attattttga
     3841 ccctgttgat tttaatatag agcaagatat ggatgtagtt gtagaaactg caagaggctt
     3901 ggagtatggg aaagtagtcg ttggtccaaa agatatggat gaaagcgaat tagtttctcc
     3961 tttgaagcca attataagaa tagctacaga agaagataaa aaagtatatc tagaaaataa
     4021 ggaaaaggca aaagaaactt ttgagttgtg ccaacaaaaa ataaaagaac atgagttaac
     4081 aatgttttta atagattgtg agtatacatt tgataggaat aagttgattt tttactttac
     4141 agcagaagga agaatagatt ttagagaatt ggtaaaagac ttagctgcta tatttaaaac
     4201 tagaatagaa cttagacaaa taggtgtcag agatgaagct aaatctatag gaggtctagg
     4261 gccttgtggt agaaaacttt gttgttcatc ttggttaggt gattttcaac cagtttcaat
     4321 aaaaatggca aaagaccaaa gtctatctct aaatccaaca aaaatatctg gaatatgtgg
     4381 gagattattc tgttgcttaa aatatgagca tgatgtatat agtgaagcaa tagaaaaaat
     4441 gcctgttgta ggtgcattgg tgcaatcaga tgatggaaaa ggaaaagttg tagaagtgaa
     4501 tcctttatta gaacaaatta aagtggaatt tcaagacaag acagtaaaga tatacacaag
     4561 agaagatata aaaatactta gagagcctaa aaaatgtgat ggctgtggtg gtaaatgtaa
     4621 ggataatgat ggattagatg aagccacact aagagagcta aagaaattag aagattaaat
     4681 ttaaggtagg gcttttccta ccttttttaa agcaattaat gcttaaagtt attaatattt
     4741 gaggagaatt tatatatgca attaaaagat tcagaaagaa tagatgattt acaattaaaa
     4801 ggccttaaaa ttatacaaga tactaatggt ttttgttttg gtatagatgc agttttatta
     4861 gccaatttta ctaaaataaa aaaagatgcc aaagtagtag atttgggtac tggaactgga
     4921 attataccta ttttgatagc tggaaaaagt gaagctaaaa aaattattgg cgtggaaata
     4981 caagaagatg tatatgaaat ggcaactcgt tctataaaat taaatggatt agaagaaaga
     5041 gttgagatta taaatgaaga tataaaatac atagacaaag tcttagacat aaatggttac
     5101 catgtagtca catcaaatcc tccatatatg catattgatg gaataaaaaa tccaaatgat
     5161 aaaaaagcaa tatcaagaca tgaagtaagg tgcaatttgg aagatgtaat tagagctgca
     5221 tccagattgg ttatgcctag aggaaaattc ttcatgatac atagaccaac aagattggtt
     5281 gatataataa ctttagggag aaaatataaa ttagaaccaa aggttattca atttgtgcat
     5341 ccaagacctc aaaaagcacc gaacttagtt ttggttcaat ttgtaaaaga tggaaggcca
     5401 gagcttaaaa tattggaccc attgtatgtt tatggagaag atgggaatta tacaaaagaa
     5461 ttaaaagcaa tatataataa taaagatata ggagagttgt aaatgagtgg gaaattgtac
     5521 atatgtccaa caccaatagg aaacctagaa gatataacat atagaacttt aagaacatta
     5581 aaagaagtag acttgattgc agcagaagat acaagacata gtataaaact tttaaatcat
     5641 tttgaaatct caaaaccact aactagttat catgaacata ataaggattc aaagggagat
     5701 tatttgataa ataaactaat tgatggtgaa aatatagctc tgataagtga tgcaggtatg
     5761 cctggtatat ctgacccagg agaagagata ataaaacaag ctatacaaaa taacatagag
     5821 atagaagtat tgccaggtgc aacagccttt gtaacggctt tagttggctc tggtatggac
     5881 acacatagat ttgtttttga gggcttttta gatagagata aaaaagttag gaaagcacaa
     5941 ttggaagaat taaaggaaga aagtagaact ataattttct atgaatcacc acatagattg
     6001 aaggatacac taaaagatat gcttaaaatt cttggtaata ggaatatttc tataaataga
     6061 gaacttacaa aaaaatatca agaaataata agagaaaata tagaaactac cataaaaata
     6121 tttgaggaaa aagaaataag aggagaattt gtattaatag tagagggttt tcatggtgag
     6181 aagtcaaaga aagaaaatta tgatgggctt acagataggg aatatgtttt aaaactaatt
     6241 gaaagtggta tgaacaaaaa agatgcaata aaaatagttt gtaaagatag aaagttaaag
     6301 aaagatgtgg tttataaaca agttttagat ttataaaacc tgaatctgag gtgattttat
     6361 ggaaataggg aaaattataa tagagagttt aaagagggaa gatacacata aaatatttat
     6421 agaattagat aataagcatg aattagaaaa aataattcct aaaataagct gtatgaagtc
     6481 tgtaggtgaa tgtaaatatc atgtagtaaa ttgttttgaa cattctataa acgcattaaa
     6541 agaattagaa atagtattaa atgataagga tttttttcca atacatctaa gaaaacatgt
     6601 gtcaaactat ttaaacacat atattgaaga aggaataaat aagttacatg tattaaagct
     6661 gggaacattt ttacatgata taggtaagcc tgacagtatg accttagatg aaaccggaag
     6721 agttcatttc acaaatcatg aaaaaatagg tgctcaaata attgacaata tgggaataaa
     6781 gttagagtta tcaacagaga catatagact tataagtaaa tatgtaagat atcatatgat
     6841 acttttgtct ctatataaga aaaatgattt gagtaggaaa gaattaatta atgtatttaa
     6901 cttagtagat gaggacacta taggtgtaat aatgcttggg tatgcagata tagtgtctac
     6961 agtaaaatta ttgggcaaga gtggagaagt cagtgtgtta aagacatata tggaatatat
     7021 tttaacaaat tacttgtata agagtaatta tacacatgta taaatttagt taatataatt
     7081 gagttttaga tgattaattg aagtttgaaa tatacggatt tcaaaaacat aaaagaagtt
     7141 gtctttgttg taaaattatg aaagacaact ttttttatat caaaaattga aattttatta
     7201 aggatactta atggtctatt aattaataaa ccattagtat ttaatttata ttacaatatt
     7261 gattttgctt gtattggcgt tgatagtata acagaggtct tagtagaacc aattttcttt
     7321 atagtatcaa tcacattttc taactcgtac atatctttta caattacttt taaaagtaag
     7381 caatcatcac ctgttatatg gtgacattct acaatcctag ggtcctttgc agctgactca
     7441 ataaattctg tatatccatt gcttggaaga gaaatatgaa taaatgcctt tataactctg
     7501 cctaatgaat ctgggttgac aatagcttta tatccttcta taacaccaga ctcttctaat
     7561 cttttgactc tttctgaaac tgcaggagaa gttaaaccaa ctatttttcc taagtccttc
     7621 atagaaattc tcccatcatc ctgtaaaatt tctatgattc tgtaatctgt aacatccata
     7681 aataaacagt cccccttaaa taaaaataat taatgctata aaactttttt agaatctatc
     7741 atttgtgttt ttaaatacca aagatttcta gataaatcaa ccttataaat gtgtggtttt
     7801 gaaagtcttt tgtattgttc ccagatagta cttaattcat attgtacatg attttttatt
     7861 tcaagaacag cttttttatt atatttgcat ctgcctttta tatacaatgg tttaagaagc
     7921 tctttaactt tgtaatttgt aaataccttc gttttccatg tataagtagg atggaagatt
     7981 tctaaaggtt tagactcatc tataacttca tcatgtaaca taatcaaatc tgcctctgcc
     8041 ttattgtctt cgttatatat tcttataact ttcttgtaac caggattatt tattttttct
     8101 ggattctcag aaatctttat cttaggttca agaactcctt tttcacaaga tgcagctaat
     8161 ttataaactc ctccaagaga aggtgaatcg aaagatgtaa tgagctttgt acctactccc
     8221 catgaattta tagtagctcc ttctgcttta agtgatgtta tggtatattc gtctaggtca
     8281 ttagatgcag tgatgctgat atctgaaaag ccagcattat ctaattgttt tttagcttct
     8341 ttagataaat aagctaaatc tccagagtca agtcttatac ccataggttt gtatcctttt
     8401 tcagaaatat ttttgaatac ttttattgca ttaggaactc cactgtttaa tacatcataa
     8461 gtatctacaa gtagtaggca tttatctgga taaacatcag catatgcttg gaatgcttca
     8521 agttcattat caaatttttg tacccaactg tgagcttgtg taccaattat aggtatatca
     8581 aacattttcc ctgctagtac gtttgcagtt ccagcacaac caccaactac agcagcccta
     8641 gccccatata tccctgcatc tggaccttgt gcacgacgta atccaaattc aaatacaggg
     8701 tctccttgag ctgcaaagca aactctagag gctttagtag caataagaga ctgaaaatta
     8761 actattgtta acaatgctgt ttcaataagt tgagcttgat ataaaggtgc cttaacagta
     8821 attaatggct cattagggaa catgatagtt ccttcctcaa cagcatatat atctcctgtg
     8881 aatttaaatt cttttaaaaa ttttaagaac ttgtcagaaa ataaatttaa gttttttaag
     8941 tactctaaat cttcatctga aaaatgaaga ttatctatgt attcaacaac ctgatcaata
     9001 ccacaaacta tagtataccc tccatcacaa gcgttttttc taaaaaacat atcaaataca
     9061 acaatgtctt catgaatatt cttttcaaaa tagccattta acatagtaag ctgatataaa
     9121 tcagtaagaa gtgttagatt tctcattatt tctctcctta attattatta aatattaaaa
     9181 attgtaaaaa ctcccacact tatactaaaa cataatatag tacaactttc aagtataaag
     9241 tattacctaa ctatcataaa attatttaaa gaggaggatg attataatag gaaaaatatg
     9301 gttttatatg gtatcgatag gaataatagg aagcttgatt tctaaaaata tgggtgaatt
     9361 aaataaagtt atattaagtg aaacatcaaa aggtatagag tttgcaataa gtctagctgg
     9421 tatcatggca ctctggatgg ggataatgaa tatcgcaaaa gaatcaggtt taattgaaaa
     9481 gataggtcaa aaactaaatc ctataatgag aagattattt ccttctattc caaaaggtca
     9541 taaagcaatg tcttatatag ttatgaatat tgctttaaat atgttgggtg ctggaaatgg
     9601 tgcaacagca tttggtttaa aagcaatgag tgagcttcaa actttgaata acaagaaaga
     9661 tacagccact aatgatatga ttatgtttat ggtaatcaat atatcatcta tacaaataat
     9721 tccatttacc ataatcaaac taaggatgga tatgggggct caaaatccaa gtgaaataat
     9781 ttttacgact ttatttgcaa ccataatatc tacagcagta gcaataataa catgtaaatt
     9841 ttttcaaaga agatatagat aaaggggatg tagatacatg gagatatttt caaacttact
     9901 tataccaata ataattctgt acatagtaat ttatggtaaa tataaaaaaa tagatgtgta
     9961 tgatagtttt gtaaaaggag caattgatgg attaaaagct gcatgggata tcctaccata
    10021 tataataggt atatttttgg caataggaat attcaaaact ggtaaaggtc ttgatatgtt
    10081 agaatggcta tttacaccaa tagcaaatat gatgagtata ccaaaagaat taataggtct
    10141 aataagtgta aaacctttat ctggaagtgg tgctttaggg atgtacagtg aacttgcaaa
    10201 tagagttgga ataggaagtt tagtagaaaa aatgggtgct acgattgtag gttcttctga
    10261 gactattttt tacacaatgg caatatacta tggaagtctg aagataaaaa atactagaca
    10321 tacattatca tgtgctatga ttagccatgt tgcaggtgtc atagcagctg tttttatttg
    10381 ctatgtaata tttgtataat ttgttgacaa tatgggaaaa attttataat atagtgatta
    10441 tatagaaaca aatagtaata caaattacaa gctatgaaaa gaagagtaaa taaaggtttt
    10501 ttctatcaga gagctaggtt aggtgaaagc tagtgtcaaa agctttattg aagatggtct
    10561 tggagctttt tatctgagca agtgtgctag ggtaaaacgg ttggacacgt tatagtctac
    10621 taaggtatct ataaaatgtt tctacatttc atgtgaaaca taactattat agatgaatta
    10681 gggtggtacc gtgaataatc tcgcccctat gttaactcat aggaggcgat tttttattat
    10741 ttaaatgaaa gaatcatatg attacgaacg ataaaaaatt aggaggtaaa taacatgagc
    10801 aaaccgagtt tttatgtaac aacaccaata tactatccaa gtggaggatt acacatagga
    10861 catacttatt caacagtagc tgcagataca atagctagat tcaagcgttt ctgtggatat
    10921 gatgtaaagt tcttaacagg aacagatgag catggtgaaa aaattcaaaa gaaagccata
    10981 gaacaaggaa tgtcagagat agagtatctt gatggaatga taaaagatat aaaggcctta
    11041 tggaatacta tggatatatc ttatgatgat tttataagaa ctacagaaaa aagacataca
    11101 gacataatac aaaagatatt tactaaacta tatgagcaag gtgatatata taaaggtgaa
    11161 tatgaaggta gatactgtac tccttgtgag agtttctgga cagaatctca attactagaa
    11221 ggaaataaat gccctgactg tggaagagaa acatatttag taaaagaaga atcttatttc
    11281 tttagattat ctaaatatga agacagatta aaagagttat ttaaagatga tagtttctgt
    11341 tttcctgctg ctagaaaaaa tgaaatggtg gcaaactttt tagacaaagg attagaagat
    11401 ttaagcgtaa ctagaacgac ttttgactgg ggtataaaag ttccttttga tgaaaaacat
    11461 gtaatttatg tgtgggtaga tgctttatgt aactatataa cagcattagg ttatatgact
    11521 gataatgatg aagaatttaa aaaatattgg cctgccaatg ttcaaatagt aggtaaagaa
    11581 atagtgagat tccatacaat aatatggcca gcgcttttaa tggctttagg tctagaagtt
    11641 ccaaaacaag tatttggaca tggatggata ctatttgctg atgataaaat gagtaaatca
    11701 aagggtaatg tggtttatcc agaacctata atagaaagat atggaataga cacacttaag
    11761 tacttcttat taagagagtt tgcatttggg caagatggaa gttatactca tagaaatttt
    11821 gtaacgagaa taaattatga tttagcaaat gatttaggaa acttaataag tagaactgta
    11881 gctatggttg aaaaatacaa taatggtata ataccaacag caaaagtttc aactgatttt
    11941 gatgctgact taaaagaaca agctgtttca actagagaaa actttgaagc tgaaatggat
    12001 aaaatgcaat tccatgaagc attagagagt gtatggaaat tagttagaag aactaacaaa
    12061 tatatagatg aaactatgcc ttgggcacta gctaaagatg aaacgaagaa agatgaatta
    12121 gacacagttt tatataattt atgtgaatct ataagaataa tcgcaacact aataaatcct
    12181 ataatgaatg agactgctaa taaaatatat gaacatatag gaataaaagg tcaagatgat
    12241 ataactacat gggaaagtac aaaaacattt ggtcttattg gagaaaatgt aaaagtattt
    12301 aaaggtgaac ctttattccc aagattagat gtagaaaaag agatagaaga attaactaaa
    12361 atgttctctg ggaaacctcc agtagaagaa aaacctttag agcataaaga agaaattact
    12421 attgatgatt tagacaaaat agagcttaga gtagggaaaa taataagctg tgaaaaacat
    12481 ccaaaagcaa ataaattatt agtatcacaa gttaagattg gaccagaaac aagacaaata
    12541 gtatcaggaa tagctgaata ctataagcca gaggatttag taggaaaaga ggttacagtg
    12601 gtatgtaact taaaaccagt taaattaaga ggtgtagaat ctcaaggtat gatattagca
    12661 gcaggtgatg atggagaccc atatgtttta ccatttacac aaggggctaa agatggatgc
    12721 gaggttcgtt agtaggtaat taaatagtaa ggagattaaa gatgttattt gactcacatg
    12781 cacatttaaa tgatgaaagt tttgatgaag atagagatga acttattggt tcattaaaag
    12841 ataaaggtgt agatttggtt gtaaatccag gagcagatat agagacgtcg ataacagcaa
    12901 ttgaacttgc gaaaaaatac gactttatat attcagcagt tggggtacat ccacatgatg
    12961 tatcaaaact agatgataca gcaatagaaa ctctaagaaa acttgcaact gagaatgaaa
    13021 aagttgtagc tattggagag attggattag attattatta tgattattct ccaagagaag
    13081 aacaaaaaga gtggtttaag aagcaaattg aattagctaa tgagctaaaa cttccaataa
    13141 taatacatga tagagatgca catggagata cttttgagat aataaagaat actaaaaatc
    13201 ctgaaatagg atgtgtactt cattgttata gtgggaatgt agagttagct agagaatatg
    13261 ttaagatggg ttgttatata tcaattccag gcacggttac ttttaagaat aataaaaaaa
    13321 ctagagaagt agtaagagaa atacctctag aaagattatt catagagact gattcaccat
    13381 atatgtcacc agagccacat agaggaaaga gaaacaatcc ttcccaagta tcttttgttg
    13441 ctgataagat agcccaggaa aaagggatat cttatgaaga agtatgtaga gttacaaaag
    13501 aaaatgcaaa gaaatttttt aatataaaat agacaaatta aatcttataa tgatatatat
    13561 aataagtcat tataagtata ggatgagagt gcctcaaaat gagtttttta gttcatgagg
    13621 cactcttttt tgtatgaaat caaatatatt ttcatcattt caacaatgaa aaagaagttt
    13681 atcatatttt gagatagttt gtttttattt atttaattca tattttaaaa tatattttct
    13741 taacattgtt aaaaaagaat ttacaagaga ttcattagaa ttaactcaac tctaatattc
    13801 acttaactta agttgtttat tatattatta aagagaagta aacgaaaggt agattaagga
    13861 ggttgaattt tgtatacagt tgatagtact aagatattga taaatatgaa cttagagaaa
    13921 ctagaaaaga tatactcaat gataaaagat acatcaagta tttctataat taaagaacct
    13981 aacttggcta cagtaatggt aagagctaat gaaagtgtaa aaaacacaac atttaattta
    14041 ggagagatat tagttactga atgtagtgta aaggtagatg aaagcttggg ttacggaata
    14101 gtttcagaaa acaataataa gaaagccatt tatttagcag ttatagatgc agttttacat
    14161 agcaataaca gtaaatttga tgagttaaag aattacataa ataaaagtgt atatgaagag
    14221 aacttaaggt atgaacaaga gattattgat gaatttagct tgattaataa aacgaaagtt
    14281 caattcaatg ctatggatta aataggagga gaatcatggt aaattataca caagaaatat
    14341 atagaaagat gctagatagt gcttcatttc ctgggaaatt aaataatata gataatataa
    14401 atatagaaaa taatacaaat ctattgaatg gagcaattgg tatagcaatc actttattag
    14461 accaagaagt taccttctat atagaaaatt atactcaaaa agatataaaa aatataagag
    14521 cacttacaat gtcaaatcaa atagattata gaaaatcaga ttatatattt ttagatatta
    14581 attcagaagt ggatatatta cagattaaaa taggttcttt tgaatatcct gatgaaagtg
    14641 caactatagt acatcaagta aatgatttat caacgtactc tcaaactaag tatataaagc
    14701 ttgatttgag tggtcctggt ataaaatcta aaaatagtat atatataaat ggaattagag
    14761 aagaatttat agaaagatta tctagtataa ataaagatta tccaatagga atagatttga
    14821 ttttagtaga taaaaaagga gaaattgcat ttataccaag gtcatcaaaa ttaagttggg
    14881 aggtattata gaaatggctt atgtagcagt taaaggtgga gaagaagcca tattacaggc
    14941 taaaaatata cttgagtttt atagggtaaa aggagatagc ttgcctatag atgtaaagca
    15001 gattgaggaa caaatgtctt atgctgtaga caaagtaatg tctgaaggaa gtttatacaa
    15061 caaggaacta tcagcattgg ctataaaaca agctcaaggt gatatattag aagcctcttt
    15121 ctatgtaaga gctttaaggt caacaatgcc tagaattaca tattcagaac ccataaatac
    15181 agaagaaatg agaataaaaa gaagaatatc agctactttt aaagatatac caggaggtca
    15241 gtatcttggg gcaactagag actatgaaaa tagaatattg aatgtagaat tattagaaga
    15301 agatgaaaaa aagaatagac attttagaga tagttttata aatgaattag aaacagtaga
    15361 tgaaatccct gaatttacaa aaatatctaa tatatttaga aaagaaaatt tattacaaga
    15421 agaagtttgt gaaaacaaat tggaagaagt tattgatgat attacaagaa atagtttaag
    15481 atttccagtt tctagggcag caaagttaca ggcattaact agaggtgaaa gcggagtagt
    15541 atcaggtttt gcttatgcta ttgtaagagg ctttggtgat gaacatccat atataagtga
    15601 acttagaact ggcaatgtgt ttataaaaat aaaacatccc atctatgaag atgaagaaat
    15661 aacaataggt gatatgttgg ttactgaatg tgaaatagtt tcaaaagcat cgcaaaataa
    15721 gactgaaaat tctaaaaata attcggaaga taaaaataaa atgtctttag gatatggtct
    15781 ttgtatgggg aacaatgaga ataaggctat atctatggct atactagaca aatctttgga
    15841 gccaaatagt gaaaaactag cacaagacga agaatttgta ttgcttcata tagatggaat
    15901 agattcatta ggatttatat ctcactttaa gcttcctcac tatgtagatt ttaaagcgga
    15961 tgtagaaaga ataaaaaagt ttgaggaggt aagtttaggt gatatataac tatggttttt
    16021 tagacgaaaa cacaaaaaaa gaaataagaa gaaagatatt aaaagcaata tcaatacctg
    16081 gttatcaagt tccctttggt tcaagagagt tgcctatagc taagggatgg ggtactggag
    16141 gtttacaatt aacactatca ttaattggta aaaatgatgt agtaaaagta attgaccaag
    16201 gaagtgatga ttctacaaat gcttgtaata taaggagctt tattgcaagt gtaagtaatg
    16261 tagaaaccac aaaagataca ttagaagcta cattgattca aacgagacat agaataccag
    16321 aagaaaaact taaatctaat caaatactaa tatttcaagt accaatacca gaaaccctta
    16381 gaatagtaga acctagtgaa gtagaaacaa gaagaatgca ttcagaagaa gattatagta
    16441 ggatgtgggt atatctttat gaagatatag ttagatttaa tgatatatct atagcagttg
    16501 aatatccatg taaagtaaat gatagatatt taatgaatcc atcacctata cctagatttg
    16561 atataaaaaa attaaatatg tcagacaatt tattcttgtt tggtgcaggt agagaaaaaa
    16621 gaatttatgc tattcctcca tatacaaagg tagaaccttt agagtttgag gattataagt
    16681 ttgaagagga aaagtttgaa ggaaaatact gtagtttatg taacagtaca aatacatttt
    16741 tagatgaagt atatgacagt gacactaatg aaaagtacta tagttgctca gatacaagtt
    16801 attgtgaaaa agttagatta aaaaataaca gtatagatgt gacaatagga ggtacttgga
    16861 atgagtaaaa taaatgactc taaaagatta gaaaatatag acaagcaagt attaatagga
    16921 agaaatatca atcttattta tggagatggg tgtgaaaagt gttttgaaag cacaggatat
    16981 gaaagcaata atatatgtaa gtattgtggt tctatagttg catgtaataa tgtaaattta
    17041 gaactttatg aaggagaagt ccttggaatt gtaggtgaat ctggttcagg aaaaagcact
    17101 ttattaaaaa tactgttttt ccaagaacat gcaaatagtg gagaagtata tatatcccat
    17161 tacaataaag acacaaatat actagagctt tcagaccaaa aaaagagata cataaagaat
    17221 cattttatgg gtattgtgta tcaaaatccc caccttggtt taaatttaga ctttagtagt
    17281 ggtggtaata tagcagaaaa attattgatg gcaaatttat ataatgttga aaaaataaga
    17341 gatagaggca aagaactttt aataaaaact aatatacctg tagaaagaat agaccataaa
    17401 ccaaaatact ttagtggggg aatgcaacaa cgagttcaaa tagcaaaagc tctttcaaat
    17461 aaccctccaa tattgctatt agatgaggtt acaacaggtt tagatgtttc tgtgcaagcg
    17521 gaagtattgg atttaataag agaaatccaa agagaattta agatttctat gatagttgta
    17581 tcccatgact ttgatgttat aaagatgctt gctgatagga caattgtaat gaaaaatgga
    17641 agtgtaattg agtctggtct tacagaccaa ataatggagg acccacaaca cccatatact
    17701 cagcaactta taaattcatt gctataaata tcgtttgtaa ataagcaaaa tgggggtttt
    17761 taataaaatg aaagaaacta tacttgaagt aaataatttt agtaaagact ttgagttaca
    17821 tgcattgaac aagactataa cggcatgtag taatataagt tttgaagttt caaaaggtga
    17881 gtttttagga ataataggta aatctggagc aggtaagtct accatattaa aaagtatcta
    17941 taaaacatat ataccaacaa ctggagaaat aatttttaat tcagaaatat atggtaatgt
    18001 agacctggct aaaattggag accgagaaat gataaatctt agaaagaaag aaataggata
    18061 tgtatcacag tttttaaaga cacttccacg aataactgca attgaactgg tagtacattc
    18121 tttaattgag agtgggtttg aaaaggattg ttcgtatgat atggcaaaag atatacttaa
    18181 ccaatttgaa ataaaggaaa atttatggga tgcgtatcca aataattttt ctggtggaga
    18241 aaaattaaga ttaaatttag ctcaagctat ggttaaaaag cctagacttt tgttacttga
    18301 tgaaccaact gcatcacttg ataatcaatc taaaatatat gtaaaagaaa aaatgttgga
    18361 gcttaaaagt caaggaacta caatgatagg aatttttcat gatatagagt ttatggaaac
    18421 tgttatagat aagaccttta ctatgacaaa agggactata agtgaaagtg gggtagccta
    18481 gatgataaaa ctaattcata atgcaaatat tgtattagaa gatatgattt tagaaaatgg
    18541 tcatttaatc atagagggag atacaataaa aaaagtatca aatgataaga ttgattacgc
    18601 atttgacttt aatgagatag atgaaataat agatgcaaaa aacttatatg taatacctgg
    18661 tattatagat attcacagtg atgccattga aaaggaaata gagccgagac caagtacatt
    18721 attaccattt aatatggcat tttatgaact agataaaaaa ctacctgcaa atggaataac
    18781 tacagtttat cattctatat ctttagggga tggagtagga gttagaagta ttgataactc
    18841 tttaaagatg attaaaaata ttgattcata taaaaatata gatagtaaga gcataaatca
    18901 taaagttcat ttaagatatg aagtgttgta ttatgaaggt ttagaaaagg ttttagaact
    18961 attagatgaa aataaaatag actacttatc aataatggac cattctccag gacaaggtca
    19021 gtatacaaat ccaacatttt ataaagagta tgctactaaa gtgtggggag ttacagaaaa
    19081 ttatgtagat acatggttag atgatttagt aaatctgcat gataatttag attggaataa
    19141 aatagctaat attataggta tagccaaaac taaaaatata aatgttgcat cacatgatga
    19201 tgatacatta gaaaaaatgg atttcataaa aaatataggc ataaatgtat ctgaatttcc
    19261 tataactctt gaagttgcaa aacattcaaa gaaattgggt gttctaactt gtttaggtgc
    19321 accgaatatt gtaagaggta aatctcataa taacaattta aaagcaatgg atgctatatt
    19381 ggaagattgt tgtgacattg tgtgttcgga ttatcttcca tcagctatga taaagtctat
    19441 gtgtatagtt gcagaaagaa taaataattt aaataaagca gtcagtttat ttacctcaaa
    19501 tcctgctaaa gcagttggta tatatgatga aagaggtagt ataaaagaaa ataaaaaagc
    19561 agatttagtt ttagtagata ttgatagtga atatccaaag gttgtaaata ctattgtaaa
    19621 tggaaaaaca gtttataaaa gggaggtata aagattgcta acagagttac attgtcatac
    19681 aagtatatca gataataatt ttactactga agaaataata aaaaaagcag cagaaaagaa
    19741 tataaatatc ttagcaataa caaatcatga cacattatct ggattggatg aagctcttgt
    19801 gcttggagag cattatggaa taacaataat accaggtata gaaatttcag cctatgatta
    19861 taaaaataga aaaagagttc atattcttgg atataacata gatttaaaca gtcaagaaat
    19921 aaaaaatttg tgcaatccaa tggtatgtga cagacataaa gcatctgtta agatggtaaa
    19981 taaaattata gatttaggat acaaaatatc tttggaagat gtaaagaaat attcatcaaa
    20041 gactggaata tttaaacaac atataatgaa agctcttata gataaaggat atacagataa
    20101 tatatattca agtctatata aagaattgtt tcatagagga aacggcaagg tatatgtatc
    20161 tttaaaatat gtggattaca gagatgcaat aaaagctata aaaaattctg gtggaatttg
    20221 tgtgttagct cacccgggtc aaatggataa ttttagcgct attgaagaga tggtaaaagt
    20281 aggattagat ggaatagaag tatatcatcc atctcacaac aaagaactag aaaaagagtc
    20341 gctttcttat gctaagaagt ataatctagt ggtcacagga ggctcagatt accacggatt
    20401 ttattctcaa cataattatg aacttggaag caagagctta aataaagaag atttatttaa
    20461 gtttaggtta gctttaggag gggtattata aatgtctttt ttacaagtaa aaaatgtagg
    20521 taaaagttat ggacaagtta aggtgttaaa agacatatct attgatattg aaaaaggaga
    20581 gtttatttgt ttactaggtc caagtggttg tggaaaaagt acactgctta gaataattgc
    20641 agggcttgag gataaacatg gtggaaaaat aataataaat gataaggata tgactaattc
    20701 accacctgaa agtagaaatt ttggtatagt ttttcaatca tatgcattat ttccaaatat
    20761 gaatgtttac aaaaacatag cctttggact agaaaataaa aacataagta aatctaatat
    20821 tgataaaaaa gttaaagaag ttctagaagt tgtagaatta agtggatatg agaaaaaata
    20881 tccatcacaa ttatcaggtg gacaacaaca aagggttgca ttagctcgtg cgattgcttt
    20941 agagccagac tttttacttc ttgatgaacc tttatctgca ttagatgcaa aagtaagact
    21001 taaacttagg gagcagatta gaagtttgca tagaaaacta ggcattacaa ctataatggt
    21061 aacgcatgac caagaagaag ctctttgttt agctgataag atggttgtta tgaatagagg
    21121 agaaataata caagttggaa cgccaaagga ggtatataaa aatccagaaa caccttttgt
    21181 agctgatttt ataggaacaa taaattttat agatgatggt attaataaga tagctattag
    21241 accagaagat ataaaagtag agtctaatag agattctaaa gataaggata taaaagtggg
    21301 agaaatttta gatatcgaat ttagaggatt taactataga attacagttg agtatcgttc
    21361 taagcagatg aaattagatg tagtttccaa agttgcagaa caaatgaaac tgtgtatagg
    21421 ttctaaaata aactttaaga tacctaaaga aggaattgta caatataaat cagagggatg
    21481 tgcttaatag ctaggggtga ataaatgata acatcaaaaa ataaaagaag aataagtgat
    21541 agcacaatac aaaaatattt cttgattttt tcggtaattg tactaatagt atttatatta
    21601 tttccattag tatcattatt aaaaaatgca tttatggata caagtggaaa ttttatagga
    21661 atttcaaact ttagtaaata tgttgaaaat ccaagtctta tagcatcatt taaaaattca
    21721 atttttgtat ctacagtctc atctttaata tcactatgtt tagcatttat atattcatac
    21781 gcaataacaa gaacaaacat aaagtttaaa gaatttttta aaactatggg aatgtttcca
    21841 ctttttgcac caactatgtt atatggtatt tcacttatat acctttttgg aaataaggga
    21901 atctttacaa ccatgggtct ggaagtacca ctatatggtc cattaggaat aattatttct
    21961 cagattctat ttacatttcc acaagctttt ttaatattat ctgtagcact ttcgatggct
    22021 gattacagac tttatgaagc agcagatagc ttgggtgcta gtgaatttaa gaaattttgc
    22081 aaaataacaa ttcctggtat aaagtactca ttacttagtt cattctttgt atcctttata
    22141 cttgcattta cagattttgg agcagctaag gtagttggag gaaactacaa tgtactggct
    22201 actgacatat ataaacaagt agttggacaa tttaacatac caatgggagc tactgtttct
    22261 atggtaatgt taattcctgt actaatagca tttacattag ataagatggc aagtaagaaa
    22321 caaggtatga ccataactgc aaagtctatg ccatataaga ttaaggaaaa taagtttaga
    22381 gatagagtat ttttaatagt atgtagtttt ataacattgc taatttttat tttaatattc
    22441 gtttcagtta taggttcagt tataaagtta tggccatata atttaagctt tacaatggaa
    22501 cactatacat ttaaaggtat tttgggaagt ggaataaaaa catatttaag cagtttgaaa
    22561 atatcaactt taacagcaat atttggaact atatttgtat tttttagtgc ttatatgata
    22621 gaaaaggtgg ataagtttcc taaattaaga caaacagctt accttttatc aatgatacca
    22681 atggccttac ctggcttagt tttaggtata tcatatataa ctttttttaa ctcagcaagt
    22741 aatccattaa attttttata tggaagtaca gcaatattag ttatagtaaa tgtagttcat
    22801 ttttattcag tttgttttat aacctcaaat tcatctttaa aaatgttgga taaagagtat
    22861 gaattagttg caaaatccat aaatattcca ttctataaag tattttttaa tataacagtt
    22921 ccaatgtcta taacatcaat acttgaaata gtagtatatt attttgtaaa ttcaatggtt
    22981 actgtttcag cattaatatt tttatataca cctcaaactc agactgcatc aatatcaata
    23041 ctaaagttag atgagatagg atatatagga ccatcagctg ctatggcagt attagtgctt
    23101 ttaacaaata taatagtaag acttttgtac gaatttgtaa caaagaaatt aaaaaataac
    23161 acacaaaaat ggcagcaaaa agatgttgca taggggaggt aaaaatgaaa tttaagaagc
    23221 tagtttcttt aggagtatta tcaacacttt tattaagtgt aataacagga tgtagtactg
    23281 attcatcagg ttcagattca aagtctgata gtaagacaaa aggggattta acagtttaca
    23341 cagcaattga agaagatagt atagagccat atttagctac atttaaagag aaatatccag
    23401 atattaaatt aaatattgtt agggcatcaa caggagatat aacagcaaga ttattagcag
    23461 aaaaggataa tcctcaagca gatgttgtat ggggagttgc agccacaagc ttattggttg
    23521 cagatgacca ggggatgtta gaaccatatg ctccaaaagg ttctgaagaa atagagtctg
    23581 catttaaaga tgataaagaa gttccttctt gggttgggat agatgcttgg atgacaggta
    23641 taacagtaaa cactaaagaa ttaagtgata agaacatccc agttcctagt tcttacgaag
    23701 atttaataaa gccagaatat aaaggtctta tatctatgcc taatccatct tcttctggta
    23761 cagggtactt aacagtatca gcccttatac aaattatggg ggaagaaaaa gcatggcagt
    23821 atatggataa gttacatgag aatattggtg tatacactca atctggttca gctccagcta
    23881 catcagcagc ttcaggagaa tatcctattg gtatatcttt tggatataga ggtataaagt
    23941 taaaagagga aggctatcca gtagaagtag tatttccaaa agaaggttct ggatgggata
    24001 tagaagcaaa tgctcttgtg aaaaaagata atataaaaga agcatcaaaa gtatttttag
    24061 attgggctat aagtaaagat gcaatgaacg aatactctaa aaactatgca gttactacta
    24121 tttctacagg aaatccaata ccagaaggat tccctaaaaa gccattagag caaatgatag
    24181 ataatgattt aaaatcagca gcaaaaaata gagaagatat actaaataaa tggatatcaa
    24241 aatatgatgg taagacagaa aaagagagtt aagtaaaact atacaaatgg agtaaaaaga
    24301 aaaatttttt ttaagtagat tttattatta taatataagt tgagaataat ataggtcaag
    24361 aaaagtgaat attctataaa aatgtataga gtaagtatac cattcagttt gaatggtata
    24421 ttttttattt ttagagatta atttagaaat agatatacta cagtttaaaa tagtatattt
    24481 taatttcatt attaaagtat agatgttata tataaagtaa ataagatatt aaataattat
    24541 aaactaaagt aaataaaata ttgagcgatt attaaaaaga tatatatata atttaatttg
    24601 agcagtttgt tatatattat aaaaaaagag aaaaataaaa ggtaaattgt ttctggataa
    24661 cttaaaattg gaagtaagaa tatttaacta gagaagaatt atttaagttt aggttagctc
    24721 taggagtagc tgattttata ggaacaatag attttatgga tgatgatata aacatggtag
    24781 caattagacc agaagatata agggtagaat ttaatagaga tttcaaagaa attatagacc
    24841 tcaaactcag accgtatcga tataaaaact aaagttagat gatatagtgt tgtagatagg
    24901 accatcagct gttatggcag tattagtgct tttaacaaat ataatagtaa aacttttgta
    24961 tgaattgata ataaaaaaat taaaaaccaa gacataaaaa tggcaacaaa aagaagttga
    25021 ataagggagg taaaaatgaa atttaagaag ttagtctctt tgggaatatt atcaacactt
    25081 ttattgagtg taataactgg atgtagtaat gtttcatcag gttcaaactt aaagtctaat
    25141 aataagacaa aaggagagtt aacagtttat acagcaattg aggaagatag tatagataca
    25201 tacttagcta catttaaaga gaaatatcca gatattaaat tgaatgtact tagattatca
    25261 gtaggaggta taacagcaag attattagca gaaaaagata atcctaaagc agatgtgtta
    25321 tggggtgttg cagctacaag tttgataatt ttagatgaca aagaaatgct agagccatac
    25381 gctccgaaag gctttgataa ggtaaattct gcatttaaag atgataagaa agttccttct
    25441 tgggttggaa tagatgcttg gatgactggt ataacagtaa atactaaaga attaaaagct
    25501 aaaaatatat cagctcctag ttcttatgaa gatttaataa agccagaata taaagatctt
    25561 atatctatgc ctagtccagc ttcttcagga acaggatatt taacagtatc agaactcata
    25621 caaattatgg gtgaagaaaa agcatggcag tatatggata aattgcataa aaatattggt
    25681 gtatacactc agtctggttc agctccagct atattagcag cttcaggaga atatcccatt
    25741 ggtatatctt ttggaaatag aggtataaag ttaaaaggtg aaggttatcc agtagaagta
    25801 gtatttccaa aagaaggttc tggatgggag atagaatcaa atgcacttgt gaaaaaagat
    25861 aatataaaag aagcatcaaa agtattttta gattgggcta taagtaaaga tgcaatgaat
    25921 gagtattcta agaattttgc agttactaca attgacacgg gaaatccggt gccagaagga
    25981 tttccaaaga atccattaga acagatgata gataatgatt taaaatcagc agcaagaaat
    26041 agagaggcta tactaaataa atggatagaa aaatatgatg gaaagacaga aaaagagagc
    26101 taagccttgc aataaaattt agtacaaaaa gcgcctagaa tataagtttt atatctaggc
    26161 tcttttgata tatttattta aaatgcatat ttctatataa aaataaatag tttagtacct
    26221 tgattaaatt aaataaaaac cttaaaataa agagatgtaa agaaaaacta aaaacgaata
    26281 aaaggtgaat ttatatgata aaagaaataa tagtagtaga gggtagagat gacgttacag
    26341 cagttaagag agcaatagat gcagaactta taactacagg tggatttgga tttccaaaag
    26401 gtgtaatgga gcgtataaaa gctgctaatg aaagacgtgg tgttataata tttacagacc
    26461 cagattttgc aggtgaaaaa ataagaaaaa aaatagcatc agaagttcca ggatgtaaac
    26521 atgcatttct accgagagag gaagctaaaa aggatggaga tataggtatt gagaatgcta
    26581 ctcctcaaag tataatagca gctctgaata aagttagaac tgaaaataca gaaaaaagag
    26641 atgaatttaa gcaagttgac ttaattagaa atggtcttat aggtaatgaa gaagcatcac
    26701 ttagaagaga tgcacttgga aaaatacttg gaattggata tggaaatgca aaacaatttt
    26761 taaatagatt gaataattat ggagttgaaa gagaagaatt tatagatgca ttaaaacaaa
    26821 tctaaacgta atgtttaatg tatgaaaaat atgtatataa aataaattgt ggaattacgg
    26881 ttaatttaag atgaattatt tataatatac accttatttt aaatcaatgt aaatacatat
    26941 aaataagtat aattaataaa attaaatatc aaaataagtt aaaaaggagt aaataatgga
    27001 tagactatct tcacataatg caacaaagga agtagtacaa aaatataatt ttaaattttc
    27061 aaagtcttta ggtcaaaatt tcttgataga tagtaatata attgataaaa tcttatctgg
    27121 agctagaatc acaagaggag ataatatcat agaagtagga cctggtatag gaactcttac
    27181 tcgtgagatg ggtaaaatag cagaaaaagt agtggctata gaaatcgata gaaatttaat
    27241 tcctatattg aaagatacct tgtcagattt agataataca gaggttgtaa atcaagatat
    27301 actaaaagta gacatacagg aattagtaaa agataaatta aatggtgggc cagttaagct
    27361 tgtagcaaat cttccatatt atataactac tccaatagtt atgaaatttt tagaggaaga
    27421 catacctgta acagacatag tagtcatggt tcaaaaagaa gttgcagata gaatgaatgc
    27481 tattccgggt actaaagatt atggggcatt atctatagct gttcaatact attgtgatac
    27541 agagattgtg gcaaaagctc caagacatat gtttatacca caaccaaatg tagattccac
    27601 agttataggt ctacatgtaa gagataaaag aaaatatgat gttcataatg aagacatatt
    27661 ttttaaaaca gtaaaagcat cctttggaca aagaagaaaa actcttctta attcgttggg
    27721 aggtcttggt tttcttaata aagatgaaat aagagaagta ttaaaagaag ctaatataga
    27781 cgaaaaaaga aggggtgaaa ctcttagtat agaagagttt tcagttcttt caaatataat
    27841 aaatacaaaa gtatcttcta aatagaaggt acttttttta attttgttaa catatattgt
    27901 ttagagaaac tgtgttaagg ggggattgca gtgggttcta aaagaaagtt taaaagagac
    27961 tatataatac tagaagctaa agacataaac tttagataca aagaacgagt actgccaaaa
    28021 gcttttgcaa aagttgaagt aaatgatgaa aaagcaatta ttgcattata tgtagaaaat
    28081 ctaaaatatg ttaaagatgg gtataaagca gtagcaataa aagatgacca tggattaata
    28141 gacttaggaa atataatttt aaatgaacaa ggaagaggtg aatttgtttt agatttagaa
    28201 gattatgatg atgagataaa aggtattgca ttattgtatg aaagaaatat acctttaatt
    28261 ggatttaaag gaaataagct tgaaaattat gaggacatat tatttcaaga ggtagaggaa
    28321 gaagaatatg aagaatatga agagttggaa gaagaagacg aagagataga ggagaatgag
    28381 gaaagtgata gagacgaaga tagtgaagaa gaatatatta tagaagaata tgatgaagat
    28441 gagtatgaag actattggga agatgatgaa gatattgaag aaggagagtt aaaagcaaga
    28501 acggaagtag aagattctga tgatgaggaa atagaagagt tcaataatta taaggaaata
    28561 gaaaattata atagggttaa agtacaggaa gaatatatag acatagaata tgatgaagaa
    28621 gaagaggaag aagaagtttt tgaagtaaat agagaagaag ataggtttgt ttcctcaaaa
    28681 cctactaaat caaagaaagt tcaaaaagat cagaataata ttgaaaaaat aaaaagagct
    28741 aatggagtaa gtcaaggaga gagtggaaat aaacaaacca gtacattact tatgccaaga
    28801 caaataaaaa aaggtttgaa attatttaaa gaagtaaaac cttttgtaac agattatata
    28861 gataagacaa gatggtggaa aatagagata aatcctacaa cactgtgtgg atatacaatg
    28921 ccttatttag gatatttaaa cgtattgaat tacactatgt atagtgatgc agttttacat
    28981 tcatataaat acagacacta tttatttgga gttcagtatg atgaatataa taagagaaaa
    29041 cattatattt atgctatccc aggaaataga aatgaacagc cagacaatgg aagcacagga
    29101 tttttaagat atcaagcttg tgataataga acaaatagtt taggatattg gctatgtttt
    29161 atagattcta gacaaagaaa tatagttagg taaaaataat aaaaatgaaa aaatttagac
    29221 tcaattctta ttttactgaa aaaattaatg aaatgtagta caaaacttta aaaactattg
    29281 ataatattta aatattacac tacaatatat cttgaaatac ctattatatt atggaggaaa
    29341 attatgataa acgagcaaag aattttaaat gagtttcttg aattagtaca gatagatagt
    29401 ttatctttaa aagaggggaa tgttgctaaa gtattagtta aaaaattaga agaaataggt
    29461 tgttcagtag taatagacaa tgctggtgaa aaagcaaatg gagaaactgg taatataata
    29521 gctacattaa aaggaaataa agaaggaaag aaaatattat ttagttcaca tatggataca
    29581 gtaactccag gtataggggt aaaacctata gtggatgaag caaatggaat aataaaaagt
    29641 gatggtacta caatattagg ttctgatgat aaagcaggta tagcagctat attagaaggc
    29701 ttaagatata taaatgaaaa taacatagaa catactgata tacaagttgt attctctata
    29761 tgtgaggaat gtggattagt tggagctaaa aatttagact atggaaaaat agattctgaa
    29821 tatgcattta tattagatag tggtggttct ccaggtgaaa taatagtaaa agctcctgca
    29881 caagatgtaa taaatgttaa gatattagga aagactgctc atgcaggtct tgaacctgaa
    29941 gctggaataa gtgctataat ggtagctgcc agagcaatag aaaatatgaa tttacttaga
    30001 atagacgaag aaacaactgc taacatagga attataaacg gtggaacagc tacaaatata
    30061 gtaacaggag aagttaatat agttgcagaa gccagaagtc taaaagaaaa taaattagat
    30121 gttcaaacta aacacatggt agagactttt gaaaaagctg cgaaagattt tggagctcaa
    30181 attgagatag atgttaatag agcatacaca ccaatagatg ttagtgagga ttctgaaata
    30241 ataaaacttg caaagaaggc tttttcaaac ttaggtatag aaggtcatac tgaatctaca
    30301 ggaggaggta gtgatacaaa tatattaagt aagaatggta tcgaagctat aactttagga
    30361 attggtatga aaaatgctca tacactaagt gaacatatag ctataaaaga cttatatgat
    30421 tctgctaaaa tggtagtgga gataataaag gaagcataaa tttaaataat agtgtataat
    30481 atatatatcg cctagcttaa gctaggtgat ttttcatttt atagaagatt gataatctct
    30541 attgaaagca aagagtatac atttgcatat aagagagtgt ttaatttatg ttcaaatgta
    30601 ggttcttaat aatatttaga ttgtttcata agggaggaat aaatatggaa acaaggtatg
    30661 aagaagcaaa taaaataaca atacaatcaa tactttggaa tatagtatta acaataatta
    30721 aggttatagc tggtgttatt ggtaattcta gcgctatgat tgcggatgga ttacattcag
    30781 catcagatat tataagttct ataggagtac taataggcaa ttatgtatct tctagacctg
    30841 gagatagaga gcataattat ggtcatgaga aagcagagac attagtatca tttgtgttat
    30901 caatattgct tattttcgtt tctataacaa taggtataga ggcaattaaa tctttattta
    30961 acttagatgc attaagtgtt ccatcaatat taccattagt agtatcagtt atttcaatcc
    31021 tgataaaaga gtatcaatat agaataacaa taaaagttgc taaaaagata aattcaccag
    31081 ccctaaaagc tgatgcttgg catcacaggt cagatgcttt atcttcagta gctgctttta
    31141 taggtatagg tggttctatt ttagggttta aaccattaga cccaattgcg tcagttgtag
    31201 tggctatatt tgtagctaaa gtaggaatta gtatacttat aagttctgtt aatgaattga
    31261 tggatgtttc agttgatgaa gaagagataa aagaattaaa atttattgta gcagatacag
    31321 aaggtgttaa aaatcttggt gatataaaga ctagaaaaca tggagctatg gcatatgtag
    31381 atttgactat atgtgtggat gaaaatttga cagttaagca aggtcatgat attgctacca
    31441 agcttgaaaa acatataata aaacatatgg aatttgtaaa aggtataaca gttcacgttg
    31501 aaccatgtac taattgccaa ggaaataagt gtaataatta attaaaactt aaaaaaaagt
    31561 gtaaaaagtt atataattgt tttatgatta taaactctag gggtggttaa atgagcaaga
    31621 aaagaaaact aaagaaaaaa gctgcaatat taataggagt agttgttttc tttataatat
    31681 actttatatc ctttagaata ggaataaata tggaaaagga taaaagtgaa gtgccaaaga
    31741 aggtagaaaa agaagaagaa gataataggt ctttaaggac tcaaataaaa gagaagaaga
    31801 aggtttatat atcagataaa aatatagaaa acataaaaat tgaagaagat atgtgggatg
    31861 aaataaagtt atttttctca gattttaaga aagtaagaaa tactacttct tcttacgaag
    31921 cagtttatga aggttattct gatgatggag ttaaattttc tactgacctt aactttttta
    31981 gagtatatac tgtaaataaa gaagaatatt ataaagtacc agttagttct aaggatgctt
    32041 ttaagaaact tttagatgag agtatatata cttcgtttga ccttttaagt cattataaag
    32101 attggaaaga ggttactata actcatggaa aagaaattaa aaaagttcat agatggaaat
    32161 ttgatgattt agcacataag atgatttcaa agagggttgt aggaaaagtt caacctgaga
    32221 aaagtaagga aagaagtgac tataatttta ctataaatat aaaaggtgat aattttgatg
    32281 taaaagttga tacaatggga aaagattatg taaaagttac ttctaagaaa aatgtatctt
    32341 actatgaggt tcatacaagt ttatttgatt accttaaaaa tgagatattt gaaattggaa
    32401 agaaataaga ctttaagaag gctatcaaat tagatatttg atagcctaaa ttattttata
    32461 tattattttt caaccaacaa gtctgcaacc ttataaattg gaccagcacc agcagttatt
    32521 actaaatcat tatccttaac attttcacgt aagtatttta ctatatcttc aaattctttt
    32581 atatagatgg catctacatt gttttgatat aatttctcaa ccaagtcctt agaatgtata
    32641 tctcctgggt ctttttccct agcagcatat atatctgtta tgataacttt atcagcagca
    32701 tagaatgcct ctgaaaattc acctaaaaga gattttgttc tagtataagt atgtggctgg
    32761 aagatacacc ataaagttga tttttttaat tttttggcag cagctaaagt tgcttttaac
    32821 tcagttggat gatgtgcata atcatctact actaaagcat tcttatagta ccctttagtt
    32881 tcaaatcttc ttccgacacc tttataaatt tttatatttt ttcttatagt ctctaagtca
    32941 ataccagaaa caagagctgc cattatggca gaagaagcat tgtatatgtt atgaagacca
    33001 tatacagaaa gttcaaattc tcctaaatct cttccttcat attctattct aaatattcca
    33061 tgaccactat tgtcaaagtg aatatctttt attacagcat cattgtcaga atctctgccg
    33121 tattttataa tagtagcttt aacatcatac aatatgtcat caatattttc atcatcgcca
    33181 tttattatga aatagccttc tgggggtaat aattttccaa atttgttaaa agaagccttg
    33241 atttcatcta ttccagagaa ataatcaaga tggtcttctt caacatttaa aactatagat
    33301 atctttgggt taaaattaag gaaactatct acatattcac atgcttcagt tataaagtgg
    33361 ttggaattac ctatcttaac attaccacct atcatactta agttaccacc aactagtata
    33421 gttgggtcta agtctgcata ttcaaagatt gtagataaca tagatgttgt agaagttttt
    33481 ccatgtgttc cagaaactgc tatagaattt ttatattccc tcatgatttg gcctaaaaaa
    33541 gttgctctgt tcattaccaa tttatttttt tctttagcag ccacaagttc ttcattgtct
    33601 ggatgaactg ctgctgtata aacaaccata tttacatcat ctgatatatt atcttttttc
    33661 tgaccaatat aaatagttgc cccttggtcc ctaagtttgt ctaataggta tgattcgttt
    33721 gaatccgaac ctgaaacttg ataaccttta ttgatacata tttcagctaa tgcactcatg
    33781 ctgataccgc caattcctat aaagtgtata ttcataataa aaccaccttt ctttttaatt
    33841 aagtcctaca atatgaacta tttctgtggt ataataatat aatgttcaat attttataat
    33901 taatatgcat ataatattat atgtatttta tttttgaata taataaaaca taagtaatat
    33961 tataccacaa taagaattgt tatgcattag ttagtttaac gttatataaa ggtacttgta
    34021 ggaggaaata ataatgaaat ttaaaagaac agagagaatt ggagcaatag ttaaaatact
    34081 gtctgataat ccaaataaaa tatatacttt aagttatttt acaaatcaat ttaatgcagc
    34141 aaaatcaaca ataagtgaag atttattagt tgtaaaaaat gtatttgaga agctacattt
    34201 aggtaaagtt ataactattt caggagcagc aggaggagta aaatatatac ctaaaacttc
    34261 tatagcagaa aatgcagagt tcttaatgga attatgcgag agaatatgtg acaagtctag
    34321 aatactatct ggtggttttt tatacttgat tgacctaatt tacgacccta caatagctgc
    34381 taagatagga aagatattcg catcaaatat tgagtatgta gatgcagatt atgttgtgac
    34441 aatggaaaca aaaggtatac ctatggcact tatgactgca aaagctatga atttacctct
    34501 agttataata agaaaagata taaaggtatc agaaggtcct acacttagca tgacatatgt
    34561 gagtggaaac agttctaaag ttgaaagtat gagtttgcca agaaaagctc ttaaaccaga
    34621 tagtaaagtt ataattatag atgatttcat gaggggtgga ggtactataa aaggaatggt
    34681 agaccttatg aatgaatttg gtgcagaggt tataggtact ggagtattca tatctacaac
    34741 gaatccttca gaaaaaatgg taaaagatta tatttcattg attcaattgg atgttaatgg
    34801 agataaaata gtagtagaac caaacttaaa gacttttaaa gatgaatata gaaatgaaga
    34861 tttagacgaa gaagaagatt cagaatttga atttgagata gatgaagatt aataaaaaaa
    34921 atatttagaa aaatatgtaa aaataaaaag aggatatccc tagttgttca tagaattatt
    34981 taaaaaacag tttatattaa tttattccag cgataataat tttaatataa attaatttct
    35041 gtcaaaatca aagggggata ttttggtatg aagataactg acgtaagagt aagaaaatta
    35101 acagaagaag gtaagatgaa atgtatagtt tcaataactt tcgataattt gtttgtagtg
    35161 catgatataa aagttataga aggccataat gggctattta tagcaatgcc tagcagaaaa
    35221 gtaggcgaag gaaatttcag agatatagct catccaataa atgcagaaat gagacaagtt
    35281 ttagaagatg cagttttaca agcgtatcat gaagcattag ttcaatggga agtagctgct
    35341 gaataataat aaatatataa aatggagaga gcccgaacat ttaggctctt tttaaatgta
    35401 gaatttctat taaaatatgt actttttagt aaaaaagtgc tatattatta gtgataatgt
    35461 atatgttgta tacaaattgt tagataaatg tattataatg tatattgatt aagagaataa
    35521 tacgaataaa attaaattag attgaatgga gtgtatcaat gaactttaaa gctataatcc
    35581 ttgctgctgg caaaggaaca agaatgaagt ctaaataccc aaaagttata cataaagtat
    35641 gtggaaaaga aatggttaac catattatag atgtttcaaa aaaatcaggg gtaaaagata
    35701 ctgtcgtgat tttaggacat gaagctgatg tagttaaaga aaagcttgca gaagaaatta
    35761 taatagccat gcaaacagaa caacttggga caggacatgc tgtaaagatg gctaaagaat
    35821 atattaatga tgaagataca atagttgtac tttgtggaga tactccactt ataaaagaag
    35881 agacactaaa gagactattt gaatatcata tagaaaataa atatcatgct acagttctta
    35941 caacaagagt tggaaatcca acaggttatg gtagaataat aagagataag aagggtgacc
    36001 ttcttaaaat agtggaacaa aaagatgcaa attcagaaga aaagatgata agtgagataa
    36061 actctggaat ttattgtttt aatggaaaga gtcttagaga agcactagat ttgctaaata
    36121 ataacaattc acaaggtgaa tattatttaa ctgatactgc taaaataatg agagataaag
    36181 gattaaaagt tggtgcattt gcaggttcaa ctattgaaga acttatgggc gttaattcaa
    36241 gagtagaatt atcaaaggca gaagaaatta tgagacgaag aataaatgaa tctcatatgg
    36301 taaatggagt aactataata gacactaact ctacctatat agaatctgat gttatgatag
    36361 gcaatgatac tataatatat ccaggtgtta tgttacaagg aaaaacaagg ataggttcag
    36421 attgtataat tggaatgaat tcatctataa caaattcaga aataggtgat ggtacagaaa
    36481 taaaaaattc aactataatt gatagtaagg ttggagaaaa ttctactgtt gggccatatg
    36541 catacttaag accaaagagt gacttaggaa ataatgtaaa aataggcgat tttgtagaag
    36601 taaaaaatgc tattatagaa gatggctcaa aagcatctca cctttcttat ataggagatg
    36661 cacatgtcgg taaaaatgta aatattggat gtggagtagt atttgtaaac tatgatggta
    36721 aaaataaatt taaatcaata gtaaaagaca atgcgtttat aggttcaaat tctaatttag
    36781 ttgcaccagt agttgtagaa gaaaaaggat atatagcaac aggttcaaca ataacacatg
    36841 atgtcccaga tggtgctttg gcaatagcaa gagaaagaca agttatcaaa gaaggatggg
    36901 tagaaaaaaa gaatcaaaaa gacgaccaaa gtaagtaatt atgtagttta ttattttggc
    36961 taaaaaattt agctcgaaat tattataaat tatattcatt agtattttaa aattttcagg
    37021 agggttacat aaatgaatac tagcggaagc gagattaaaa ttattgcagg taattcatcg
    37081 aaagagttag cacaaaaaat agctgactat ataggtgtat cagtactaga ttgtgaagta
    37141 ggtacattta gtgatggtga aatatgtgta aacatgaatg agacagtaag aggttgtgat
    37201 gtgtttgtag tgcaatctac taacagccca gtaaatgata acttaatgga gttattaatc
    37261 ttaattgatg cgttaaagag agcatcagca ggtagaataa cagcagttat tccttactat
    37321 ggatatgcaa gacaagacag aaaggctaag gcaagagatc caatcactgc taaattagtt
    37381 gcaaatttaa taactgctgc tggagcagat agagtattaa caatggattt acatgcagct
    37441 caaatacaag gatattttga tataccatta gaccacttac taggtggaac aatattagca
    37501 aattatttta atgaaaagaa aatagaagat ttagtagtag tatctcctga cttaggaagt
    37561 gttactagat caagaaaatt tgctaatact ttaaatggag aagttccaat agctataata
    37621 gataaaagaa gaccgaaagc taatgtatgt gaagttatga acttaatagg tgatgttaaa
    37681 ggtaaaaatg ttatactatt agacgatatg atagatacag caggaacaat agttaatgct
    37741 gcaaatgcac ttaaagagtt tggagcaaaa gatgtttatg cttgttgtac tcatggtgtg
    37801 ttatcaggtc cagctattga aagaattgct aattcagaaa taagtgagtt aatagttctt
    37861 gatactatac aacttcctga agagaaaaga atagataaga taaagataaa aacagtagct
    37921 cctttatttg gagatgctat aagaatgata ttctctaatg aatcagtaag taaattattc
    37981 taatttattg tatttatgag agttgtttaa aaggatataa accttttgag caactctttt
    38041 ttgattttat acttatggaa tgttattttt ttcttgttag aaaggtatat attattgtaa
    38101 aaagagatta tagtttaaaa ttatgtatat ttaagtaaaa taaacctaat aaagggtata
    38161 ttattcaaaa tattatgaat ataaaaaata ttacaaaaaa gtattgaaaa aattcagatt
    38221 atgtagtatt atgtaaatat aaataaagaa agaggtgttt ccaatgggaa ggttagaaga
    38281 tgaaccccta ataattaaat gattcagtca caatctaaag tgaatataaa aatctattga
    38341 aagtttattt ataagaattg aaaatagtat ctattctatc tttagtgttt gtgagagggt
    38401 tctggattat ataagattac tgtaaagagt aattttgcac aataagcata tctgtaaatg
    38461 aagagtttcg tttatataat gattgtggct gaatcataac tataatagat agaatgttta
    38521 taatagatga ttttataaaa tactatattg taatagcttt tagctttcaa ataaatatta
    38581 gcaaaggatg gaaatgacaa tgataaaact aaatgataat ttataaatat ctccttacga
    38641 tatataataa ttgtagggag atgtttcttt ttttgtatag cataattttt ctagaaattc
    38701 tgtttcaata tgtaaaaagt tggtatatat aaatagtata aacagtgttg ctaaaatatg
    38761 gtagatatta tataatataa gtggatatgt atatacatta tgagttatat aatttgaatt
    38821 taataaaata gaaacgttga tttatgttct gtaatgtggg caccttggag catattgagt
    38881 tagtggtgca accggctatg aaattgtatt tatttataaa tactattatt ttcatagctt
    38941 tttttattta aaaaatggtt atatgttaga aataaatttg gttagtacgt ttaaataatt
    39001 ttacttagat ttttaaccag atatattgta agtaagtatt aattaaaaaa tttaaggggg
    39061 aataaaaatg aagttaaaaa agaataaaaa aggtttcact ttagtggaat tattggtagt
    39121 aattgcaatt ataggtatat tagcagtagt ggcagttcca gctttattta gtaatataaa
    39181 caaggctaag gtagcaagtg ttgagtctga ttatagttca gttaagagtg cagcattatc
    39241 ttattattca gatactaata agataccagt tacaccagat ggtcaaactg gtttaagtgt
    39301 tttagagact tatatggagt ctctgcctga taaagctgat ataggtggaa aatataaatt
    39361 gattaaagtt ggtaataaat tggtattaca gataggtaca aatactgaag gagttacatt
    39421 aacagaggca caatcagcaa agttattgag tgatataggt gaaaataaaa tatatacaag
    39481 cgctacaaca aatagtttgg gaaatccatt aacaagtaat acaaaaatag ataataacgt
    39541 tctatatata gtacttatag ataatactgt gatggacaca acaaaatagt taaaacaata
    39601 tttttataaa aatattgtaa atttaatgaa aaatataata taaaagacag gaagaaaatc
    39661 ttcctgtttt tttatactat tttctttaat gttcaattat gaatgatgat ataattgaga
    39721 tagtaaagga gtgaaacctg tggctaaaaa agttagaata ggagacaaac tggtcgaaaa
    39781 aggatatata acagaagaac agcttaaatg ggcactatca gaacaaaaaa acagtggaaa
    39841 aagactagga gaatttctag tacaagaagg gcttatagat agtaacttac taataagtgt
    39901 attaaaagaa ctcttggata tagaaagtat atttttagaa gggacagaaa tagacacttt
    39961 agctacaaaa atggttccag aaaatatatg caaaagatat actgtatttc catttaaaat
    40021 tgatggaaat aaaatatgtc tagccatgtc agacccacaa gatagagaag cagttcaaga
    40081 tgtaaggcgt atgtctggta aagacgtaga gatatttata tcaagtacag aagatataaa
    40141 caaagcaata ggtcatgctt atgcacattc agaaataaat aaggcaatga ctgagtacaa
    40201 caaaaataga actggtggag taagagaaac agtaatactt gaagaagatg taaatgctgc
    40261 tccaatagta cgattagtaa ataacatact agaaaatgct gttagaatgg aagcaagtga
    40321 tatacatata gaacaaagtg aaaattacat gcgtgttagg tttaggatag atggaatgtt
    40381 aagagaatat atgaggatga actcagcacc atataaggca gtaatcagcc gtatcaagat
    40441 aatgtcagat ataaatatat ctgaaaagag aataccacag gatggtagaa tctatttaaa
    40501 agtagataat aaacccatag attttagggt ttctacaatg ccaactaaca gggatgaaaa
    40561 gatagctatg agagttcttg ataagagtaa ttttatggtt agtaaagaag tactaggaat
    40621 agacgaacat ggctctaaga tatatgatga attgataaac actccttatg gtcttatatt
    40681 ggttgttggc cctactggaa gtggtaaaac cactacattg tattcaatgt taaatcaact
    40741 aaatacagaa aatagaaatc tattaacaat agaagaccct atagagtatg aattacctgg
    40801 tgtaaatcaa tctcaaataa atgaaaaggc agggcttact ttcgccagcg gacttagagc
    40861 ttttatgcgt caagacccag atataataat ggttggagag ataagagata ctgagacagc
    40921 agaaatagca attagagctt ctcttacagg acatttagtt ttaagtacat tacatgcaaa
    40981 tacagcagtt ggagcaattt cacgtctttt agatatggat gtggaaagtt ttttaataac
    41041 ttcatctgtt ttaggtgtaa tatctcaaag acttacacga aaaatatgtg agcattgtaa
    41101 ggtttcatat gaagcagata ttggagaaaa aaaggctctt ggtattgatg taaatgaatc
    41161 agtaactatt tatagaggaa aaggttgtga aaggtgtaat aatactggat ataaaggacg
    41221 tctaggtata tttgaaatgc ttgaaattac tccagaaata aaagagttaa tagattcatc
    41281 tgcaaatcaa agagaaattt taaagatggc tagaaaacaa ggtatggtta gcttaaaaga
    41341 ggatatagtt aaaaaagttt taaatggaaa gacaacagta gaagaaatga ttagaataat
    41401 tttgatgact gattaaagga tgatattatg aaaagtttta aatacacagt aataaaagag
    41461 gacggaaaaa agcaaactga tgtgattgaa gccaacgatt ttaatgaagc tagaaatctt
    41521 cttagaaaga gaaatcttag agttattgaa atcaaagaaa gcaaaaataa aaatataaga
    41581 ttatctagta gaaagagaaa aaaagactta ggagctgacc agataagcca cttttgtaga
    41641 cagtttgcta ttatagtatc ttctggtata aatagtattt ctggattaga aacattagct
    41701 agaaggtcaa ctaacattac attaagagaa gaaattaatc gtatagtggc agaaataaaa
    41761 gtaggttcta ctattgcaga ttcaatgctt tcatcaaaat caaagtttcc aaagttactt
    41821 ggtgctatgg tagctacagg tgaagctaca ggtaaattag atgaagtatt aaaaagtatg
    41881 gcttcatttt atgcaagtga acacagggtt aaacaaaagc ttagaaatgc tgcaacatat
    41941 ccattaatag ttttgatttc ttcatttata atgattttta tatttacaac atttatggtg
    42001 cctaagatga ttaattcaat tacaacagta ggagcaactc ttccacttat aacaagaatt
    42061 gttatggggt ttggtatgtt tatgaagaag ttttggataa tagtactttt agttattata
    42121 ttatttatct atcagtttaa aaaatatcta aaaacgtcag ttggaagggc tcataaagat
    42181 agagttataa ataagatacc tgttttagga aaaggaataa attgtatggt agctacacga
    42241 ttttcaagag cattgtatct atttgtatca acaggatacc cattagttca agggcttgat
    42301 tatattatag atagtgtaaa taacaccatg gcagagaaga ttttagcatc agctaaagat
    42361 ggaataacaa gaggagaagg cttagcagaa aatttagaga gatatacgta ttttgactct
    42421 gtgttggtac agatgatagc tataggggag cagacagggg aattagagaa tataagtaga
    42481 cagatggcag aattttatga gtatgaatcc gagatttatt taaataggat ggcctcaatg
    42541 atagagcctg ttttaataat tgcagttggt attatagttg cgatactggt tgtatcaata
    42601 ttcatgccaa tgcttagtat atatgatgcc atgtaggagg gaaaggacaa atgaacaagg
    42661 tttatgtatc atattatggc gattctattt ccatagttga gggcagatat aaacacgata
    42721 aggataagtt ttatgtaaaa aattttaatg tgttttcaat agaggatatt gcacaagatt
    42781 tttctaagga aaagtatgct ctattgagat acgcattaga aaatgttaag ttaaaatcaa
    42841 gacatgtagt tttttgttta aatacaagag atgtaatttt aaaaccccaa aaacttccta
    42901 atatggacaa aaaggattta gacggattta tgaagctaga gatggacgaa atgatggctt
    42961 tggagtcaga tgaatatgta ttttcgtatg aagtatctag tgaaacacct gataattcag
    43021 atggcgatga atcaagttta aatcttatta ttggagctat acaaaaggaa gaggtaaatg
    43081 caattgtaga gataatgcat gaatttgatt tagtattaga tagaatagat acattatcaa
    43141 cagcttactt aagaatgctt aaaaatttag actacaatga tataatggta accaatataa
    43201 gtgacaatag cacaattata aatatatata agaaagatac tttatttatt agtgataata
    43261 tacctataaa gataactgct aaagatatgg acatgcaatt attaaatgta gtagaagaat
    43321 caaaaggtct tatgaattac tattcgtcaa gaaactttgg taaggttacg gatactatat
    43381 taatattagg aaaaagatat tccaataaat taatttatga aacttttagc tctgcatttt
    43441 caagctatgt ttctcaaggc cttactgaga taatggatat atctgatatg ataactggag
    43501 atatagatga agatgatata aattcaattg tagagctttt aggaagtatg atagaaccta
    43561 aagggaaaag agattttgaa aatataaact ttttaccaat ggatatactt agaaaacaga
    43621 taaaagctaa acaaatgaaa aacatactga aaattgctcc aatagttatt ttgattcttg
    43681 ctatacctta tttatgttta attttttcaa ataatttagc aaataaggaa cttgaaaatg
    43741 ttaatggtga aataagaaat attgaatctg catattatca gattggaaat atagaaaaaa
    43801 tgatacagag taaaagcgaa gaaataaagg tatatgatat gttaattggg aaaaaggtaa
    43861 agtgggaaaa tttattggat gatatagata aaaatactcc aagtaaagtt gaactaacaa
    43921 gtttatcaac aacttatcaa aatcttggaa ctaataataa agctgataat tcaaaaagta
    43981 ataagactac aacagataaa tcaagtaaca atgaaacaaa atcaagtacg aaaagtgata
    44041 gtaatggaga taaaacagat aatgatttaa atgaagataa gactacaaat gtgtcagaag
    44101 cattaactgg aaatagtgag actaatagta ataacacaga taaagatgat aaaactccat
    44161 tgtatgataa gataccaaat gttataaata tagaaggaaa tgctaaagat tcctcttatg
    44221 taggtcaatt tttatataaa ttaaagggat tatactattt caaggatgtt aaattacata
    44281 gcataaaaag taatgcagaa gattctaact atacatttag tatgacatta tacctgaaag
    44341 aaggtgtatt aactaatgaa taaagatata tttaaaaaag atataaaaga tatatttaaa
    44401 atggaagtta gtctaaaagg gattcttata aaggttataa ttttattagc tattttatca
    44461 tatggttatt ttggacttta ccctcaatat cagaaatata ttgctacaaa aaattctgta
    44521 aaacaggcta ctgaaaaatt aaatatatat aaagagaaaa ctgcacttat gccaaaatat
    44581 gaaaaacaac ttgaagaagt tgaaagtgaa ttaaaagaaa aaagcaaaaa tcttttatat
    44641 gatatgcaag atggtctttt tttaataggt ttagataaaa aaatgaaggc ttataatatt
    44701 gacttaacca gttatgacgt tggaaatgtt aaagaatacg aacattttta tggtatatca
    44761 acaacaataa gtgttagagg tgattataga aatgtcaaaa aattaatggc ttatttagaa
    44821 gaacaaaaaa atgttactca aatactagat tatacaatga cttcatatat agaaccagaa
    44881 aaagaagagg aagaaacaac aaacaataag gatttaatta aaaatgtgaa cataaataaa
    44941 gatacaaaaa tatactgggt ggaaggcgaa aataagtggc atttatataa ggattgtcca
    45001 ttgataaaag agggagagat tctaaaaaat gacaaacttt tagataggtc tactaattat
    45061 ctatgtaata cttgtgtact tagagctgca acagaaaaag aagcaaaaaa agaagtcgta
    45121 gctccaaagg cagaaggtgt agtagatgct acatttaaat ttataatgta cactaaagag
    45181 aatactacaa tgatacttga tacagataat ccatcttcat ggagaccagg aaaatataat
    45241 ccatttaagt ctagtgcgaa ataaagctaa gtaagcttta aagataggtg atgagtttgt
    45301 acaaaaataa tgaaaaaggt cttactttat tagaagtaat aatagctgtt tttatactga
    45361 caatagtttt aagtatttct tataaagtgt tcaatggtat aacatcagca gtaaaaaagc
    45421 aacagattat tacagatgct caagtaaata ttaatctaat taataagtat ctaaatagag
    45481 atttggaaaa ctgtaaagaa ctaactaaaa ctggttcagg taataattat gaatacaata
    45541 tagagatgcc agataatgtt gtaaaatatg aagtttctat agaaactaaa aaaaatacag
    45601 aggtatattc tgtaacgaga atccaaaaca atacaattga tacagaaaat gaagttagag
    45661 aagagataat ctataatcaa ccactagttc aaaacaataa agaaatgaag gaaacaccat
    45721 ttaaaataga aaagcaaact ggtaaatcta tttatactgt aagtatatac tataatgaat
    45781 cagtgcaaga aagtcataaa aatagcaatt taaataacaa aacttataca tttgatgtta
    45841 tgtcaagaat aggataataa gaatttatta aaaaataagt aggttgataa aatatgagta
    45901 aaaagaatag tgaaagagga ttttccttaa ttgaagtgtt agtagctatg gctattatgg
    45961 gaattgtact atttgcattt tttaatatta tcaatactaa taacaaagca aacactaaaa
    46021 atgacacaga tataacttcc ttaaactatg tccaaagtga aatagaaaat ctaagagaaa
    46081 agataaaaag tggagaattt gattttgata gtttagataa actagaagat ggaactgtcg
    46141 tatatgaaaa attaatagat aaatcaaaaa aagttgtata tgataaagtt cttagtgaag
    46201 gtgatgtgag cttatatgat actccatatg aaaagattac aacaataaaa gatgaagatg
    46261 gtaatttaat cgacaaagga aatattacaa ataagataaa gactattgta gaagataaaa
    46321 gtggtcagat atataaaata gctgtaactg ggaaaagcat gaatgactat tcaagtaaaa
    46381 aagaggttaa aattgtaact gaaatattta aagataaata attttacttg ggggtgagat
    46441 tttgaggaag tggaataaat ttaaaagtga aagaggggca gctttagttt tagttttggt
    46501 tgtagtagca ttgctttcta ttgttggatt gatattttca aatcagatag ctaatagaat
    46561 aaaatctaca aagactacta atgaaggtat acaagcaaag tatttagcag agacatgtgt
    46621 ggaaaatagt attgataaag catatgaaaa attgtatgat gagcttgaga aaatggataa
    46681 tgagtttaaa agtgaaaatc aagaaaaatc catatctagg tcaaaattaa gagatatatc
    46741 agatgaagat tttaataatc aagatgagga aaatattgaa gcagaaagac ttggatatat
    46801 gaataatata aatttctatt taaataaagc ttcttcagac ttggaaaaag ctagtatgga
    46861 attgaaaaag ctatatgatt tagatatgtt ggactataga gacattgaat atgtagatgc
    46921 aaatattatt tcacatagag attctatctt agaaatttgc aagaattata cttctggaga
    46981 tattagtaaa ataaatgaat atattctgaa agaagatata gactcaacta cattgattga
    47041 ggcaaagtta gtgaataatg atattctttt aaaaatgttt ttagaagaaa ataaaattga
    47101 aaatgaacat ttaaattcag ccttttcaca tacttataag gcattagata acatttcttt
    47161 ggcgatgcaa aatatgattg agtatagaca tacgtttcat atagatgagc caaaagtaga
    47221 agtatctaat gggattccag attctcaaca atattatgaa ctaatacaaa atcctataat
    47281 aaatagtatg gagtatatct ggaatagtaa atgggataca ttagaaaaac tattggaaat
    47341 tttaccaaat caaactcaag gatttaattc tttaagagtt catttgagaa ataatgtaag
    47401 aaaatttgag aagttaagcg ataatatatc tagtggtaaa aaaaatacag caaaaaattt
    47461 cttaaagtat aaagagttat tgtatgaaat atcagaccaa tgtaatcaac taaaaagtat
    47521 gtcttatgag aaaatacctg ttaaatatga taacatggct ttgataacaa cttttgacta
    47581 tatacaaaat gagcttttag cagagataaa atgcagatta aaagaattaa aaccacaaga
    47641 aattgataaa acagaaggta ttactataaa aatacctttt tataaggctg actacgacat
    47701 gacaaaagaa ggatggccta aattaaaaga aaatggttca ggggcggagt taagcttaat
    47761 ggtaactggt gataaagatg gaataaaaga agtagaagtt acagatggta aaaaaaatat
    47821 tattggttta ggtgttgaag aaaattcaaa ttcaaagtat aaggttgacg ccattgtaaa
    47881 ctttaatcta aatatagata caaatgtagt tggaaattat gatataaaag ataaaatttt
    47941 gattaatcat gatataagtt catacaaaaa agtaaactaa atataagaag caacttagta
    48001 taaataaata ataaaataat tttattattt actactaaaa aaataagtaa actaatagaa
    48061 gatatggaga gtaaatatta tgtatattta tgatttatta gagcaaggta taagactaaa
    48121 cgcatcagat atacacataa cagttggaac aaatcctgta gctagagtaa aaggtggatt
    48181 tgtaaaacta agtgaacaaa tattgacatc agaagtaaca atgcaaatgg caaaagacat
    48241 agcaggggaa tctatgttta aagtaataga agaacatgga gaagctgatt tttcagcttc
    48301 tttaaaaaca ggagaaagat ttagggtaaa tgcatatagg caaaaaggaa attacgcaat
    48361 agcaataagg actataacag cagaaattcc aacatttgaa aaattaggcc ttccagagag
    48421 tataaaatct tttactgaaa agcataaagg attagtttta gttacaggtc caacaggaag
    48481 tggtaaaagt acaacacttg caagtatgat aaatataata aatgaaaaac aacaaaaaca
    48541 tataattaca cttgaagacc cgatagaata tgtacatcat cataaacaaa gtttagtaaa
    48601 tcaaagagaa gtaggaactg atacagaaag ttttcattca gcccttagag ctattttgcg
    48661 tcaggaccca gatgtaatac taataggaga gatgagagac cctgaaactg tttcaatagc
    48721 attaacagca gcagaaacag gtcatttagt attttcaaca ctacatacag tgggggcagc
    48781 taagacaatt gatagaatag tagacatgtt tcaaccatcc caacagcaac aaataaaaac
    48841 acagttatct acagtttgtg aaggtgtggt atcacagcag ttacttccta cagcagatgg
    48901 gaaaggcaga atagcagcaa ttgaattgat gtttgctact ccagcaataa aaaacctgat
    48961 aagggaaggc aaaacatatc aaattccaaa catgatacaa actggagtta aagtaggtat
    49021 gaaaactatg gaccaagatt taatggaact ttataaaaat ggaaagatta caaaagatat
    49081 ggcacttagt aggtgtactg accaagagtt tatgacaaga atgataggtg gagtaaacta
    49141 caatggatat tataatcgtt aatctatatg tatttatggt gggtatagtg tttggaagtt
    49201 tctttaacgt ctgtattttt aggattccag aaggtatatc tatttctaga cctccttctc
    49261 attgtatgag ttgtaatact agactaaagc caatagactt aataccagtg ttaagctatt
    49321 taatgagtgg cagaaagtgt agatattgtt atgagaaaat ttctagtaga tatgctatag
    49381 tggaattaat tacaggactt ttatttttaa cagtatttat gttatatgga atatctacat
    49441 caactattta ttatttggtt cttgtgtctt tactgattat aattacattt atagatattg
    49501 accactttat aataccagat aaaatattgg tttttggagc tatattttct atgattttta
    49561 accttttatt taaagaaatt ccagttaagg attcaattct aggtgttttt atttgtggag
    49621 gaagtgtctg gattatagtt cttttgattg aatttgtaat aaaaaaagag tgtatgggtg
    49681 gaggagatat caaactattt gcaatgctag gtttttacat gggtgttaaa aatggtcttt
    49741 tgacagcctt actaagcgtt tatgtgggag cagtctatgg aatctgtgta ataattataa
    49801 gtagaataaa aggaaaggaa tataattctg ttataccata tggacctttt atatctattg
    49861 gagcattaat aacaatctta tgtggaaagc aattacttga actttatttt tctatggtta
    49921 tatagatgat agtcaagtta aataaagttt taatttaaaa aaatgaatta aagtatttaa
    49981 taaggacaat attattatta accctattac taaagtgcta caaactatgg agtatataat
    50041 aataatttcc ttattttttg cacatttgat aaataaatct ctatgtgttt tttgtgatag
    50101 agaaaagaaa aatttataca atacgttttt tatttacata ataactgtag ttttatctgt
    50161 attaatatat ctaaaatttg ggattagtgt agaatgtgta caatatatgg ttttaattcc
    50221 atttttaata attatatcca ttgtagatta ctacacaata tatgtatatg atataacaat
    50281 agttagtggt ataatagttc aaggtataat ttttttggtc tttttcaata tagttcaatt
    50341 tgattatata aatcatatat ttggactatt gataggcttt attatacctt atattattgc
    50401 taaactaaca aaaggattag gctatggaga tgtaggtctc tatagcttat gttgctttgc
    50461 attgggaaat aattatgggt tttatgtgat agttttatca tttattttag cgtttttgtt
    50521 ttttattatt ttatacataa ctaaaatatt taaagatgta gatataagaa agcaaattcc
    50581 ttttacacct tttatttcct tgtcaacaat tttaataata tttacagagt ataatatatt
    50641 taatttttat tataatttgt tatacaaatt tatataacag gaggtaagaa atgtacgtag
    50701 tagtagggtt aggtaatcca ggaaagaagt atgagaagac tagacataac gttggatttg
    50761 atgttataga tattcttgct aaagaataca atattagtgt tactaaaata aagcataaag
    50821 ctttgattgg tgaagggaga gtaggtactg aaaaagtatt attagttaaa ccacaaactt
    50881 atatgaattt aagtggagaa acattaatag atatatataa atattataag gttgatttaa
    50941 gtaatatagt agtagtatat gatgatatag atttagaagt tggaaagata cgtataagaa
    51001 aaaaaggaag tggaggaact cataatggca tgaaatctat aactaagtgc ctaggttcaa
    51061 atgactttcc aagagtgaga gtaggtgtat ctaaaccaga agctggtcaa gacttagcag
    51121 actttgtact ttctagattt agaaaagaag aatctgataa cataaatgaa gcattagaaa
    51181 aagcggcaga tgctattgac tcaataataa gagaaaatat agatatgtct atgaacaaat
    51241 ataatggata gtgagaggga gatttaaatg aatgatgttt ttttatatcc tttgcaaaat
    51301 tcaaaagagt ataaagatat aataaactgt ataaaaaata caaaaggctc attattggtt
    51361 aatggacttt taccagtaca aaaacctcat atatcgtatt ctatatttaa tgatttatca
    51421 cgacaaatga tttttataac aagtagtgat ttagaagcaa agaaagtata cgaagattta
    51481 agtttttata tggaagataa agttgaatat ttaggttttc aagatattta tttttatcac
    51541 ttggatgcaa aggacagaaa cgaagaagcg aagaaattaa aagtattgtt aaaactagca
    51601 aataaagaaa aaatcatttt agtaacttct attgaggcag ttttaagaaa atacatacca
    51661 aaacaagttt tgctcgatag tgtatctcat tataaggtgg gagatagctt agacttagaa
    51721 aagttaactg agaaattagt ttcattggga tatgaaagag tttcaaaaat agaggggttt
    51781 ggtcaattta gtataagagg tggaattatt gatgtatttt cacttgaata tacaaatcca
    51841 attcgtatgg aattatttga tgatgagata gattccatac gaacttttga cgtatattca
    51901 caaaaatcaa ttgataaatt gcaacaattc tctataactc catctaggga atttatttat
    51961 cccgaaaaaa ctacagatgc attagttaaa ttaaaaaaag aaacaactaa aaatactgat
    52021 gaaggtacat ttcaaaatat agattatata tcaagtaaga cttattttga aggtgtagag
    52081 aactatatag attatattta tccagaagaa aacaaaagta tatttactta tttagcagat
    52141 gatgcaatag tatttattaa tgatataacg agacttaaag aaagatgcga aaattatata
    52201 aatgagttta gagaaaatta taaattaaat cttgaaagag gtctggctat taaaaaccaa
    52261 ggtaaattgt tatatcacta tacagattta gagtacttag taaaagacaa gtctgtggta
    52321 ttaaactcgc tattgccaaa gtctataaat aacttttcta taaaatctat aataaatttt
    52381 gaaagtagag aagttcctac atttaatgga aaggtagatt tgcttgtaga agaattaaat
    52441 cggctgaaat ataatggata caaaataatt ttagcaacaa ataccttaga aagagcaaat
    52501 aaattaggaa aagatttatt ggacaaaggc ttagaaacga ccatttctaa agatagagat
    52561 attgaaatta aatcttcaca agttataatt gtacctgcac acataaacag tggttttcag
    52621 tataaatcta taaagtttgt tgttataaca gataacgaaa tgataggtgt ttataaaaga
    52681 gcgtctaaga ctagcaataa aaaagttaaa aagggaaaga aaatagaatc ctttttagat
    52741 ttaagtgttg gagattatgt agtccatgaa aatagtggtg taggtagata cacaggaatt
    52801 gaacaaatta cagtcaatgc tattaaaaaa gattatatga aaatagtata tcaaggtgga
    52861 gataatctat atgtgccaat agaccagatg gacaaagtac aaaaatatat tggtgcagaa
    52921 gtagaaaaag ttaagttaaa taagcttgga acaaatgagt ggacgaaagc aaaagcaaaa
    52981 gttaaaaaag aaattgaaga tatgacaaaa gacttgattg agctttatgc aaaacgtgaa
    53041 aaaatacaag ggtataagtt ttcaaaagat acaccttggc aggcagagtt tgaatcgttg
    53101 tttccatatc aagaaacaga agaccaatta aaggctatag aagaaactaa aaaagatatg
    53161 gaatcaagta aggtaatgga taggctagta tgtggagatg ttggttatgg aaaaacagag
    53221 gtagctatta gaagtatttt taaagcttgt atggaccaaa aacaagttgc tgtattggtt
    53281 ccaacaacaa tattggccca acaacattat aatacattca aagagaggtt tgaaaattat
    53341 cctttgagag tagaagtttt aagtaggttt aaaacaccaa aacaacaaaa acagattatt
    53401 gaagatgcta aaaaaggatt agtagatatt ttaattggaa cacatagaat aatatccaaa
    53461 gatataaatt taccaaactt aggtcttgta gtcattgatg aagaacaaag atttggagta
    53521 aaacataaag aagctttaaa gaaaattaaa tctacagtag atgtacttac actttcagca
    53581 actcctatac caagaacatt acatatgtct ttaagtggaa taagagacat gagtgttata
    53641 gaagaacctc cacaagaaag acatcctgta ataacatatg ttacagagag taaggaaagc
    53701 gtaattcaag atgagataga gagagaatta agtagaggtg gacaggtatt ttttgtatac
    53761 aatagagttg aacacattga agaaatggca agtatgattc aaaaactcgt accagatgct
    53821 agagtggctg ttgcacatgg aagaatgact tctaaatcat tagaaaatat aatcctagga
    53881 tttttaaata aagattatga tgtactagtc tgtactacaa taattgaaac tggtatggac
    53941 atatcaaatg caaatacaat gattatatat gatgcagata aaatgggatt ggctcaactt
    54001 taccaattga gaggtagggt tggaagaagt tcaagacaag gatatgcata tcttttgtat
    54061 gaaaaagata aaactttaag tgagatagcg gagaagagat taaaagctat cagagaattt
    54121 acagagtttg gttctggttt taaaatagca atgagagacc ttgaaataag aggagcagga
    54181 aatattttag gttctcaaca acatggtcat atggcagtta taggttatga tttgtacgtt
    54241 aaaatgctta atgatgcaat taaaaaagtc aaaggtgagc ctattgtgga ggaaattgat
    54301 gttgaaatag atttaagtgt aaatgcatac attccagata attatatcaa agatgagttg
    54361 attaaaattg aaatgtataa gaaaatagct tctattgaaa acaaagaaga catgttggat
    54421 atacaagaag aacttgagga tagattctct gatataccta aaccagtcca gacacttctt
    54481 acaatagctt atataaaatc gttatgtaag atattaaaaa tagaaaagat aagacaatta
    54541 aaagatgaaa tattattagt tccaataaca aagtatagaa ctaaacagaa aataggttat
    54601 aatatagtta cagaattaga agaattatta gaaaagatgt gcaaggtaaa ataacttgta
    54661 aatttaagaa gggatgtttt aaatttgaaa aaagtaataa cattggtaat agctatgatt
    54721 ttggtagtat ctgtgactgc ttgcagttct agtaaaggag aaactgtggc aacagttgaa
    54781 ggtacaaaga tatcatcaga tgaatttaaa aaaactatag ctctttataa agattctatg
    54841 gaacaaactt atggaaaaga tatatgggat aaggaagttg aaaagggtgt aaaatacaag
    54901 gacaagttta aagatttaat tcttgaccaa cttataacta cagaagtaat atattctcaa
    54961 gctaaaaaag ataacttact tcctaaaaaa gaggatgttg aaaaaagttt taaagaatta
    55021 aaagacgcta tgggtaaaga tgaaaaatat aaagaacaac ttaagaaatt aggtatagat
    55081 gatgagtttt taagagacca acaagagaaa gatttagcaa tgcaaaacta tcaaagtaac
    55141 tttgctaaaa agactaaaat atcagatgaa gaaatgaaaa aatactatga tacacataaa
    55201 gatgaattta aaaaagatga ggtagaagct tctcatattt tattgaaaac agtagatgat
    55261 aataacaagc cactttcaga taaggaaaaa gctgaagcta agaaaaaggc tgaagaggct
    55321 cttaaagaag ttaaatcagg tgaggatttt gcaaaagtag caaaaaaata ttcacaagat
    55381 acttcagcaa gtgatggtgg taaattagga ttcttttcaa ggggtcaaat ggttgctgaa
    55441 tttgaagatg ctgctttttc tatgaaaaag ggtgaagtat ctgatttagt tgaaactcaa
    55501 tatggatacc acataattaa agtgacagac agaataaatg agcaaacatc atttgaagat
    55561 gctaaagaaa ctataaaaga ccaactgttg aaaaataaat atcaagaaca aatagaaaaa
    55621 ttaactaaag aagctaaggt agaaaaagat gaaaaagtaa taaataaaat cacaatctaa
    55681 gacttaaaaa aagagtaata tgcttaaaaa agctatatct ggataagata tagctttttt
    55741 tgtatatttt tcttaacaat ggtaaaaata aacttaaagt aatttatgga gggattaaaa
    55801 aatatgaaag caacaggtat agttagaaga atagatgatc ttggaagggt agttatccca
    55861 aaagagataa gaaagacatt aagaattaga gaaggagacc ctttagagat attcacagca
    55921 aaagatggag aagtcatact taaaaaatac tctccaatag gtgaattaaa tgaattttcg
    55981 caagaatatg ctgaaacatt agctgaagta ctaggatatg gagtgttgat aacagactta
    56041 gattctataa tagctgtgtc taagcttcct aaaaaagatt ataaagaaaa aagtataagt
    56101 gatgagttag aagcaataat aagtgaaaga acagtaaaat attcaaaaga taaaaacatt
    56161 ttaccattat tcaaggaaga ccaaaaagaa tatactagtc aagttatcat gcctataatt
    56221 agtgcatctg gtgactgtat aggttcaatt gtagttgttt caaaggataa agatacaatt
    56281 gcagaaagtg aagaaaaatc tttaaaaatt gctgctaact ttttaggaaa acaagttcaa
    56341 taattttatc ataaagacct tttacatgaa ggtcttttga agtttttgtg taaaatattg
    56401 aatatagcat taaaaatatg gtatattaaa gtttgttata taaacagtat ggaggttatg
    56461 ttatgaacaa taacaaaaat aaagactcct ttctaaaagg agcccttata cttgggctag
    56521 caggtgtaat cgtaaaaata atgggtggat tttttaggat tccccttgga aacatgattg
    56581 gttcagaagg aatgggatac tatcaggctg cttatcctgt gtatactcta tttttaacat
    56641 tagctactgc tggatttcca acagctgtgg caaaattggt ttcggaaaaa gttgcaattg
    56701 gaaattttaa aggtgcaaat aagatattta aggtatcaca tacagtttta ttcattaccg
    56761 gtataatatc attttgtata ttattttttg gagccgacta catagtaaca aacgtaatga
    56821 aaaatccagg tgcgttatac tctatgaaag ccattgctcc agcattacta tttgttcctg
    56881 caatgtctgc atatagagga tattttcaag ggagacaaga tatgactaag attgctgtgt
    56941 ctcaagttgc agagcaattt tttagagttg tattaggtct tactttggct tacttgctta
    57001 tgaagagtct aggtcagact tttggtgcag caggtgctat atcaggggct acaataggtt
    57061 caatagcatc tatgctttat ttggtgtttg cttatatgct agggagaaaa gagcgtagag
    57121 cagagataga tgcaagccaa agatttaaag atgaaagagt gtcttatatt tttaaaaagc
    57181 ttttaactgt tgccattcct ataacaatag gagcatcagt aatgccactt gtaaatatga
    57241 tagataatgt tattgtaata agaagactta tggaagcagg ctttacatac aaagtggcaa
    57301 attccatgtt tggtcaatta acaggtatgg caatggccac aataaattta ccagcagtca
    57361 taacaactgc aatgagtatg agcttagttc cagcaatttc taaagcatat gcattaggaa
    57421 ataagtcaaa agctagaaaa gatactaaga gtgcagttaa ggtaacttta cttatagtat
    57481 tgccttgtgc gtttggtatg gcttctttag caataccaat aatgggtctt ttatttccac
    57541 atgaaccatc ttctgtagga actattttgt ttactcttac tccatgtgta ttatttttag
    57601 gattaataca gacattgact ggtataattc agggaatggg aaaaccaata gtacctgtaa
    57661 ttgctttatg tgttggtatg ctatgtaaaa ttgtaataag ttatacttta acaggtatac
    57721 cagatattaa tgtactgggt tcagcatttg gtacagttac agcatacttt gtggcagcca
    57781 tgattaactt actatatgtt aaaaaacaca tgaatgtaaa cttttctaaa aaagaattta
    57841 taataaagcc atttataaca gttatgacaa tgtttataat ggttaagttg agttatggtg
    57901 ctttagttgg attcttagga aacagcatat ctacaataat tgcaatatgt gttggtggaa
    57961 ttgtatatgt agtagtaata cttggaatag gtggaattaa aaaagaagag attctaacta
    58021 tgccaaaagg tgataaatta tataaattgt taaaaaaagt taaacttata agataatata
    58081 ggaatatata tgcaaataaa ggaaatacta tacaaatagt aaatctcctt atttgtataa
    58141 taatataaaa ataaagtgaa atttgctaat aggagtgatg ttatgggtaa gataagtatt
    58201 gtaggtcttg gaccaggaga ctattctctt ataagccaag gtgtgttaga atctttaata
    58261 aatagcccta aagttttttt tagaacagag aaacatccaa taattgataa acttaaagaa
    58321 actatacaat acacttcttt agactacttt tatgaaaaag aggaaaattt tgataatgtt
    58381 tatttgaaaa tatctgaatt tatcatagaa gaatcagcaa agggtgacct agtgtatgct
    58441 gttcctggtc atccaagagt tgcagagaag actgtaagta taatagagag attagccaat
    58501 gaaaagcaca tagcagtaga aatattgcct tctatgagct ttgtagacgc tatgtttaac
    58561 tatttggcta tagacccatc tgagggattt aaactggtag atgcttttga aatagaaaat
    58621 tcatatatag acttggatac aagtatgata ataactcagg tatatgataa atttatagca
    58681 tctaatgtaa agttaaaact tatggaacat tatgactata atcaagaagt atgtatagta
    58741 aatggagctg gtgtcaaaga tttagaaagt aaaaagttta taaagctttg tgaattagac
    58801 agaaatgaaa acttttttga ctatttaact agcttatata tacccaaaag ttctaaaaag
    58861 atgtataata cagtacatga cttagaaata atagttaata cacttagaag tccatctgga
    58921 tgtgaatggg ataaaaaaca aacacatcaa tcattaaaaa attctgttat agaggaagca
    58981 tatgaacttt gtaatgcaat tgataataat gatatagatg aaatggtaga agagttaggt
    59041 gatgttcttt tacaggttat attccattgt cagataggaa atgaggaggg ctactttgat
    59101 ttaaaagaag tagtaaatgg catatgtaaa aaattaattc atagacatcc tcatatattt
    59161 agtggtgcaa aattagatat gtctaagttt gagaaaactt gggaagaatt aaagaaagaa
    59221 gagaaaggcg aaagtactat aacagatggc cttagaagga taccaaaaca tttaccagct
    59281 cttatgaagg ctagtaaagt tcaacataaa gcagcacttg tcggctttga ttgggacaat
    59341 gtagaagatg tatttaaaaa aattgaagaa gaatatcagg aattacttga cgaacacagg
    59401 gtcgggaata taaaatacat aaaggaagag ctaggcgatt tattattttc gatagtaaat
    59461 ctagctagat ttttagacat agactcagga gaagccttga actgtactac agaaaaattc
    59521 ataaatagat ttgactttat agaaaagagt gcaatgaact tgaataaaaa attagaagac
    59581 atgacacttg aagagatgga tgagttttgg aatcaggcta aaaaacaata aaattgtgga
    59641 aggaaatttg tcaaaaatct agaactttta tcacaaagat agaagtctat attataaaca
    59701 tttttaggag gtaaatatcg tgaataaagc tgaattagta tcaaagatgg cagaaaaaag
    59761 tggattaaca aagaaggaag cagaagctgc gttaaacgca tttatgagtt ctgttcaaga
    59821 tgcactagta aataatgaaa aagttcaatt agttggattt ggaacatttg agacaagaga
    59881 aagagctgct agacaaggaa gaaatccaag agatccagag caagttatag atataccagc
    59941 ttctaaagca ccagttttca aagctggaaa aggattaaag gatataataa atggataatt
    60001 agaaatcttg tgaaaaagtg tggataaatt tgccacactt tttctataga accaaggaag
    60061 gtgataatta tgagattaga taaattttta aaagtatcta ggattataaa aagaagaact
    60121 gttgctaaag atgcatgtga taaagggatt gtcactataa atggaaaagt tgctaaatct
    60181 tcttcagagg tgaatattgg agatacatta gaaatacaat ttggagagaa gaagatgaag
    60241 tttaagataa atgaagtaaa agagcatgta ttaaaaaatg atgcaaaaga aatgtacgaa
    60301 attttagaat aaaattaata gtcctctagt atattaatag tagtattatt gaaatattta
    60361 ctggggggat attatggaac agaacataac tttgaaagat agatcaaagc tggttatttc
    60421 gggagtcgag cacatatact cttttaatga caaaagagta gagctcaaaa cttctgtagg
    60481 cgagatggta attgaaggcg aaaacctaga tatgagcaag ctaagtatag acgaaaatat
    60541 aattagcata gatggaacta taaattctat ggtatatgca aagcctaaaa agccacaaga
    60601 gagtttcttg aaaaaggtat ttagatagat gatacctttt actcaagatg taagcatttt
    60661 ttatgctact atttatggtg gaatactcat aggggtgttg tttgattttt atagagggct
    60721 aagagggaat tttaaattca tcaattattt tgctataata tttgatgtat tgttttggtt
    60781 tctagctacg gttataatat tcgtaacaat aaaccttaca gaattttttg atttaagata
    60841 ttatcatttt gtggctttgt ttattggttt tattttatac tataacacca taagtaaaat
    60901 tgttttatca attatcaata aaataattcg ttttgtgaga aattctttta aaaaagttac
    60961 acattacata gtcagttttt taaataattt gtattacgtt ataatctatt cactacacct
    61021 actatttgat attatatttt atataccaaa catatttata gcaacaagaa aaagtataaa
    61081 aagaaaatca aataaaaaat taaagaacaa gaaaaaatca aaacctaaga agaaaaaaaa
    61141 taaaactaaa aaaagggtgt aggaaaaatg aacttaagaa aaaaattttc aggacagatt
    61201 attgttatca gtttattttt aggaatatca atttttagta tgatgacagg atttgtattt
    61261 gagtatacaa aagctaagga atataaaaaa gaaatagcaa gtctaaataa acaattaaaa
    61321 aagactgaaa tacaaataaa cagcttaaag aaagatgaaa aatcatatga aggagactta
    61381 gaggatatag caagaaaaag attgaatatg gtaaaaccaa atgaaacagt ttatgtagac
    61441 ataaatcgtt gattaaaact tgctaataag tttacagatg tattgatttt aaaatttaag
    61501 atttaataaa aaagtcattc agttaaggat ggctttttgt ttttattgag gagggaattt
    61561 cataatgaaa gtaggagcta tagatattgg gacaaactca atgagattat tgatagcaga
    61621 ttatagagat gggaatttta taaacagaaa aaaatttgtt aatacaacta gaattggtta
    61681 tggtgtggat agtaaaggat atataaaaga agatgctatc aaaagaaata taaaagcatt
    61741 aaaagaattt tctgataagt gtaatgatga aaagtgtgaa aaaatttatt gtatggggac
    61801 atctgctctt agagacagta aaaatggaga ttactttgtt aaattagcta aagaagaaac
    61861 tggaatagat gttgatatag ttacgggaat agaagaatca aatttgggct ttaagggtgt
    61921 tttagaagga atacaaggtg atgatactat tattgttata gatattggag gaggttcaac
    61981 agaatttatt gtaggtgatt cagaaggaat tatatttaat aaaagtgaga atgtaggtgc
    62041 tcttaggatg acagagaggt ttttgaagca cgatattatt gaagatgaag agtttgaagc
    62101 tatgagttca tttatatatg gtgagattga taaaacgtta aatcatataa aagacaaagg
    62161 attaaaaact cttataggta taggaggtac gattacatca ttatcagcaa tgaatcaaga
    62221 attagagatt tactctatgg aaaaaataca taatagtaaa atacacaaaa aagaaataga
    62281 agaaattcta caaaaattaa taaagatgac attaagtgat aaaaagaact taaaagggct
    62341 acaagaaaaa cgtgcggata ttataactgc tggtgtaaaa atattgaata taataatgga
    62401 aaaattagaa atagaagaaa taaccgtaag tgaatacgat aatttggaag gcttaatatg
    62461 tcaaaagtca aaaaaaatgt attaatattt tttgattttt aaaaccgatt atgacaaaaa
    62521 aaattactcc tctttgttac aattcttaat ataaacaaaa gaggaggttt ttttatgcaa
    62581 agaagtgtag cagttgtgaa gaataagact gtaaaaccaa atgtcataaa attaataagc
    62641 ggatatattg attttactac ggcggcattc gctgtgatgg gatttttact tagtaggtct
    62701 attatagtag actctgtagc tcctttagga attgcctttt ttatatgtgc atcaaagatt
    62761 gataagtaca agatacctgt attcatatca acattattag gaatattgtt atcatctaat
    62821 gattttggaa atgtagcaaa atatgctgtg tgccttacaa tatttatggc tatgaataaa
    62881 aaattaaaat tatcagattc aattgctaag gttgcattta taggtgcaat aatactactt
    62941 ccaatctcca tgggacaagc tttcttttca aataggtatg tatatggtct tcttatagca
    63001 ggagtagaag caataataat gtttatatct atatatgtgt tttcttatgg gataggttta
    63061 atggccaatg tcaacaatag gatgtctgta cggacagaag aagccatatc aataagttta
    63121 ctgctaacct ttagcataat gggaatagga gatatatctc tgtttggaat atcaataagg
    63181 accattttat cgaccgtatt gatattgctg acctcaatag taggtggagc tactatggga
    63241 gcatctagtg gtgtaattat tggtgtagca tccattttaa ataatatgac atcagctgtt
    63301 tatatgggga tatattcttt ttcaggatta ataagtggag catttaataa aataaataaa
    63361 tatttctgta tactaggata tattctaagt tggacaataa tatacctata tacttctggt
    63421 attacttcta atatgatgca attaagagat atactattag gttgtttgat agtactagta
    63481 ttgccagagc gattatttaa taagattgaa aaattaataa aaagtaatgt ggcttcaaat
    63541 gaaatcgtat acgattatat tatgagaagc aaaaacctaa ctaatagcag attgaacagt
    63601 atttataaaa cttatgatga ccttgcagat acatttgata agataagaga aaaagacaaa
    63661 gtgctagacc aaagagacat agctaatgta atagatatga ttcataatga tgaatgtaaa
    63721 agttgtagta tgagaagaat gtgctgggag tcaagattta atcatacata cactatgata
    63781 tataacattc ttgaaaaaat tgaggagaaa ggggagttaa gtctaaacga tatacctaaa
    63841 aattttagaa aggaatgtat gaaaccagag tcaatagtga aaatatcaaa tcactattac
    63901 aaaatgtttg tattagatta tgattggagt gtgaagtttt cagaaagtag aaagttaata
    63961 gcaaatcaga taagaagtat ttcaaaatcc attaaatcct tatctcaaga tttagaaggc
    64021 gacataatgc tagatataga aaaggaaaaa aatatatatg aacagttaga aagatatgat
    64081 ataacagttg ataaagtaag ttacttaaca aaaagtaaca gtgagtttga aatatcaata
    64141 gaaaagaaaa cttgccatga tggatgtatg tgtgaagata aaattgtaaa tataatttca
    64201 gacctagtag gggaaaatat gtctgttaga aaaataggat gtcactgttt aggaggtaaa
    64261 tgcaaggcaa cattcgttaa atctcaaaaa tataaggctg ttacagaagt ttcagcaatg
    64321 tcaagggatg ggcatatcct ttgtggagac aattacacat acatggagat aaatgatggt
    64381 aaatacatga tggctataag tgatggtatg ggaaaaggta aaaaagcata tgaagaatct
    64441 tctgccacta ttgatatact ggaaaaaatg atagatgcaa aaattaaaga tgagatagtc
    64501 attgatacta taaataatat gttgttgtta aagtcttcag aagagatgtt ttcaactctg
    64561 gatttgggaa ttttagattt aaaacgaggt tgtttagaaa ctataaagat gggagcgtgt
    64621 tctacttata taaaaagaga ggatggagaa gttgacttaa tatcgtcatc atcattacct
    64681 gtgggtatat tatcagatgt aaaaattgat agaaaaaatg taaaagttaa ggaaggagac
    64741 tatgttataa tggtttctga tggaattgta gatgcaggaa gaaataacaa tttaggagac
    64801 aattggttaa tatacttctt aaagaatata gagactacaa atccaaagga aatttcaaat
    64861 ttaatattgg atagagcatt agagttacaa gcgttacaaa ttgaagatga catgactgtt
    64921 ttagttacga aaatatgtac aaaataaggt ttacaagatt atgtgtataa gatgtggata
    64981 acttgtgtat aatatgttaa tagacttttg aaaaaagtat agttattaac aaaaataaca
    65041 tataaatcaa caaaatttgt tgataagtat ggcagaaatg ttaataaaat gtaaaaaaag
    65101 aaaaaacaaa agctattatc aaaagagatt catgttgaaa taactaaatt tctaagtaaa
    65161 gaaaacctgt gaatatgttg attattatgt ggataactat taattcgata tttatttata
    65221 tagtatgaat aattgaataa tatatctaaa aaaagccatc ctattattaa gtaaacttat
    65281 tgaaaggatg gctttttatg aatagaaaat tgtgcaaagc aataatacct ttatttattt
    65341 ctattttttg catgttaata ataagtataa aagctgacca aggatatcaa aagaataatg
    65401 atagagcaat tactgtcatg aataataatg atactgaaga tgatgctgaa aaaaaacaag
    65461 aaatagacta tgaaaaaaca tgttggaatt tgcaatcttt gtttaaaagt gatgaccaat
    65521 ggaaaaaaga acttaagagt tttgataaag atactaaaga gttgaaaaat tacataggta
    65581 aagtaacaaa atcgccaaca catttgtctt ttgccttaaa cattaaagaa aaacttgata
    65641 taagactaaa taaactttct gcctatgtaa aattaaaaca agatactaat aaaaattcgt
    65701 ataagtactt agatatgaat gatagtatga gtaaatccta tgggaattat atggggattt
    65761 gttcagattt agagttagaa atactaaaat tatcaaacaa agattacaag aaaattattt
    65821 caaataaaaa tataaatagg aaatatggtg catatttaag agatataaga aggaataaag
    65881 tacattattt ggatgataaa tcagaagata ttctaagcaa agtatcttca ataagtagtc
    65941 ttccaagcca agtatatgaa ttatttagaa atatggatag aaaaactaat ttgacaccag
    66001 ctcaatatgc gagtgaatta gagtcatcag atagagaaaa tagaaaaaaa gcttatcaag
    66061 atgaacttat aacttacaat gataatataa atacaattgc aggtttaatt actggtcaag
    66121 ttaaaaagaa tattttttat tctcaggaaa gaggttatga gtcttcttta gaaatgtacc
    66181 tggaatctga taatgtagat gaaaaagtat acaataattt gataaggact gtaaatagta
    66241 atatggacag tctacacaaa tatatagatt taagaaaaaa agtattaaaa ttagataagg
    66301 ttcattcata tgatatgttt gtgcctatgg ttaaggctgt tgataataat attaattatg
    66361 aaaaggcaca aagtatagta tattcagcgt tgtcaccttt aggaaaagaa tacaatgatg
    66421 tagtatataa agctttcaat gaaaaatgga tagatgttta ttcacatgaa aataaagtaa
    66481 gtggtggata ctgcttatct gtttatgaaa atcatccata tatactttta aattataata
    66541 attcattagg ttcagtttcg actttatcac atgagcttgg acatgctgta tatgaatatt
    66601 taagttctaa gaatcagaat tattttaatt caaatccgtc tatatttact cacgaagttg
    66661 catctacaac gaatgaagca ttactttacg agatgcttat aaaagaagct aaaggcaatg
    66721 atgaaaaagc ttattatata acacagtatt tagacttgat aaaagatact ctttatacac
    66781 aaactatgta tgctgaattt gaaaaaacta tacacgagtt agtagaaaaa ggaaaaagtg
    66841 taaacgcatt agtattaaat gatgtttggg gacaacttct taaaaaatat tatggacaaa
    66901 gctatgaatt agaccaatta tctaaggtcg gatgggctag aatcccacat ttttataata
    66961 gtttctatgt ctataaatat gctacaggtt gtagtgcagg agtaagtttt gcccaagaca
    67021 tcctaaagaa tggttcagat aactatatga gctttcttaa aaagggaagt tcagattatc
    67081 caataaactt gttaaaatca agtggcataa atttaactaa tacaaaaccc atagaaaata
    67141 caatcaaaaa atttgatagt ttagtagcag aacttgaaaa gctattataa acattattgt
    67201 aattcacatg gtaaatatat cgaattaatg ataaaatata ctaaaagttt aaagtcctat
    67261 caagatagga ctttttattt attaattagt gggagatgat tctatgcaag ttaaagttaa
    67321 aaaggctgta ataccagcag caggtttagg aactagattt ttgccagcta caaaggcaca
    67381 accaaaagag atgttaccaa tagttgataa gccaactcta caatacataa tagaagaagc
    67441 tgtggcctca ggaatagagg aaatactaat aataacaggt agaaataaaa aatctattga
    67501 agaccacttt gataaatctg tagaattgga acttgattta gagaaaaaag gtaagaaaga
    67561 attgttggag gtagtacaaa acatatctaa catgattaac atacattata taagacaaaa
    67621 agagccaaaa gggttgggag atgcaattta ttgtgcgagg cattttatag gtgatgagcc
    67681 gtttgcagta atgttagggg atgatattgt agataatgat gtaccttgtc taaaacaact
    67741 aacagatgca tatgaggaat atagaactac aatattgggt gttcaaaagg taaatcaaga
    67801 agatactaat aaatatggga taatagaagc aaaaaatata gaaggtagag tttacaaggt
    67861 aaaagacatg gtagaaaagc cagagtcagg aaaagctcct tcaaatattg ctattttagg
    67921 tagatatata ataactcctg aaatctttga tattcttaag gatttaccac caggtaaagg
    67981 tggagaggta caacttacag atgctttaaa aatattatct aagaaagaag ctatgtatgc
    68041 atacaatttt gaaggcaaga gatatgatgt tggggacaag ctaggatttt tagaagctac
    68101 tgttgacttt gctctaaaga aagaagacct taaggaagat tttataaaat atttgaaaca
    68161 tgtatgtagt gaatttgata aaaataacaa tgtgttatac aataatacag atgaaaaaat
    68221 agatttaatt gaagtcaatg aagctagaga acttgaaatt caaaaataat taatgaaagg
    68281 tgatgtatgg tggcaaaatc aagtcagaaa agaattaata gaataatagc tgttgggatt
    68341 gtgggaatcc tcgtaataac gagtataaca gctgttttga gtatgattgc aactatgtaa
    68401 taagataaat gacagcagtt gatatacata aatataaaaa ccatatataa cttgatgtag
    68461 tcaaaaactt acaatatttt agttatatat ggtttttaga atttataaat gtaaaaaaaa
    68521 atttttataa tagttgcata ttttaaagga aaatattatt ataagatata aatatagtga
    68581 taaatttata aaaacgtgct aagattggac ttgaaataca gtaatatagt aggtaataat
    68641 gttttaaatt ttatttattg accataatat ataaataatg atattattag acttaactgt
    68701 ttaaataaaa cttttctttt tcatgccttc aatttccaaa ataagtatgt atataaatga
    68761 atatatagat gaggaggatt tttttgattt tagatgataa agtattagaa ggattaggta
    68821 gtaagacctt agttgagcta cgagagatag ctaaagaatt aaaaataaaa tcaattacta
    68881 catataagaa aaatgagtta attgagatta taaattccaa aagtaaaaat gaggaaaaag
    68941 taaacgaaga gactaaagaa aaaaatgaag atattaaaga agacataaag aatagaaaag
    69001 aaaatataga gcgtgaaagt atagaaaaag aagttgaata taagagccct accaaatcat
    69061 acaacaagaa agaaatagat acccaaaata tttcccaaaa ccaagaacat agaaatcaaa
    69121 gaaatgacta taataagaca acgagtgtaa atgatagtaa taagtcatca aatatatcta
    69181 atagaatggt cagaaataat aataaaaact attatatgcc taaacaagtt gatgaatcta
    69241 agatagtaga tgaatttaac acatcaaaag aggatgaagt agtaggtgta cttgaaattc
    69301 tgccagatgg atttggtttt ttaagaggtt caaattattt gtctactgaa ggagatgttt
    69361 acgtttcacc atctcaaata agaagattta atatgaaaac aggagacaag attaagggaa
    69421 taactagaca tccaaaaagt ggagagaaat ttagagcact tttatatgtt caaaaaataa
    69481 atgatgaaaa ccctgacaca gctatacaaa gaaatgcgtt tgagacatta acaccaatat
    69541 ttccagaaga acgacttaca ctggaaacta atagaaatga aatagctaca agaattatag
    69601 atttaatttc acctatagga aaaggacaaa gaggattgat agtagcacct ccaaaagctg
    69661 ggaaaacagt tcttttaaaa agcgttgcaa atagcatagc taaaaatcat ccaaatgttg
    69721 aacttatagt actccttata gatgaaagac cagaggaagt tactgatatg aaagaatcta
    69781 ttgaaggaga cgttatatat tccacttttg accaagtatc aagtcatcat gtcaaggttg
    69841 cagagatggt gttaaataga gctcaaagat tagttgaaca tggtaaagat gtagtaattt
    69901 tactagatag tataaccaga ttggcaaggg catataacct tacaatatct cctacaggta
    69961 gaactttatc tggaggtatt gaccctggtg cacttcatgg acctaaaaag ttctttggtg
    70021 cagcaaggaa tattagacag ggtggttctt tgacaatatt aggaacagca ttggttgaaa
    70081 ctggttctag gatggatgat gtaatatttg aggaatttaa aggtacagga aatatggagc
    70141 tacatttaga tagaaaatta gcagaaaaaa gaatattccc tgcaatagat atttacaagt
    70201 ctggtacaag aagagatgat ttattgcttg atgatgaaga aaagactgct ctttggagat
    70261 taagaagaga aatgagtaat aattcagtaa tggaaattac agataaagtc attgaactta
    70321 taaagagaac taaggacaat aaagagtttg taaaatcaat aaagaatttg taaaatcaat
    70381 aatacaaatg caaatatgga ttatataaac taatagaaaa atcacttgaa tggcataata
    70441 agttgtgcta taataatgta gttgataatg taaaaagaaa gttaatataa ttaatttttt
    70501 taaataaaga gaagaggtga ctataatgca aaaggaaata caaccaaaat acaatccagt
    70561 tgaagtgcgt tgtgcttgtg ggaacacatt tgttgctggt tcaactaagg acgaaataaa
    70621 agttgaaata tgttcagagt gccatccatt ctatacagga aaacaaaaga acatagaaaa
    70681 aggtggaaga atcgacaaat tcaagaaaag attcaaaatg gactaatttt tataaaagtg
    70741 gagttggagg aagccaactc ctattttatt acaaaaaaac attcatattc tactttaaat
    70801 tgtctttttg tattataata ataaatatgt aaaattgagt attctaaata caataaaatg
    70861 aggtgagtgg atggcaaaac aagctgtagg tgggcaagct gttattgaag gtgtaatgat
    70921 gcagtcaaaa gacaaaagag cggtagctgt tagaaaaagt gacggagaaa tagcactaaa
    70981 agaagataga ataaaaagtt gggtaagaga taagaatata gataagatac cttttgttag
    71041 aggttctttt gttatgatag atacaatgat tcaaggcata aaaagtttaa acttttcttc
    71101 agagtttttt atggaagaag ctgaagagga taaatttgat ttatttataa agaaaatttt
    71161 taaagataag gcaaatgata taattataat attttcattg gtcatagcaa tgttactttc
    71221 tgctggatta ttcattttta tacctacatt ggtaggagga gctttttcta aagtaatgcc
    71281 taatgatttt atgcttaatt taatagaagg aatcataagg atagctatat tatttgcata
    71341 tatagtattg atttcacgaa gtaaggatat agaaagagtc tttcaatatc atggagcaga
    71401 acataaatct atatattgct atgaaaatga tttagaactt acagtagaga atgctagaaa
    71461 atttaaaaga ttacatccta gatgtggtac aaatttccta tttatagtta tggctgtatc
    71521 aataatattg tttgcatttt ttggttggcc aaatccaatt cttagaatat ttatgagaat
    71581 tatatgtgtg cctatagtag caggtttatc ttatgaggta attagagttc ttgggaaata
    71641 tgataatgga tttactaaaa ttattgcata tccaggaatg atgttgcaat attttacaac
    71701 aaaagagcct gatgatgagc aattagaggt tgctttggaa gcattgaaag cagtagtaga
    71761 ttagagaaaa ggatatttgt tatgacgata aaagatataa ttattaaata ttcagataaa
    71821 ctaaaagata taagtgatac tccaagatta gatacagagt tattgttaca aaaaacattg
    71881 ggtgttgata gattatatat tcacttaaat ctgaataaag agctaactga agaacaaaaa
    71941 acaaaattta tgggttttgc agaagaaaga ttaaatggaa gaccaatagc atatatagtt
    72001 gaaaataggg agtttatggg attagatttt tttgttaagg aaggcgtatt gattccaaga
    72061 ccagatacag aaactttagt agaagaaata attgaaatat gtagagaaaa aaaagatgta
    72121 agtatattag atataggaac tggttctgga gctattacaa taagtttagc aaagtacatt
    72181 gaaaattcta aaatcatgtc ttttgatata tcagagacag cattagaaat agctaaaaaa
    72241 aatgctatta taaatgaagt tggtgaaaaa ataaagtata ttaattctga tttatttaca
    72301 gcaataagtg atagtaacat aaaattcgat atcatagttt caaatccacc atatattaaa
    72361 aaacaagata tagaaactct gcacaaacaa gttaaagatt atgaaccata taatgctctt
    72421 gaaggtggag aagatggatt agacttttat agaagaataa cagaacaagg taagaaatat
    72481 ttaaataagt gtggaatatt agcatatgaa gttggtcata atcaagctga agatgtaata
    72541 aatattatga aaagtaatgg atataaaaaa atatacacaa agaaggatat tcaaggcatt
    72601 gatagagttg ttataggtta caatatatga tataatcaac aattgatatg ttacatttaa
    72661 tcgaggtgaa agtatgttaa aaaaattaga ggtattggaa gatacatata aagacttaag
    72721 tgaaaaaata ggtgatccgg atgtaataaa tgatcaaaaa gtttggcaga aatatataaa
    72781 agaacatgct gacttggaac ctattgttat gaaatacaga gagtataaaa gcgttttaga
    72841 tagtataaaa gaatcaaaag aaattttaca agaagagtca gatgaagaat taagagaatt
    72901 agctaaaatg gagttagctg agatggaaga aaaagtagca cctctggagg aagaaataaa
    72961 aatactatta ttgcctaaag accctaatga tgataagaac gttatagttg aaattagagg
    73021 tggagctgga ggagatgaag cagctctatt tgctggtgat ttatttagaa tgtactcaag
    73081 gtatgctgaa agaagaagat ggaaaataga attattgagt gcaagtgata ctggagttgg
    73141 tggatataaa gaagtatctt ttatgataaa aggtaaaggt gcttattcaa gattaaagta
    73201 tgaatctgga gttcatagag ttcaaagaat accatcaact gaatctggtg gaagaataca
    73261 cacatcaact tctactgttg cagtattacc agaagttgaa gatgtagagg ttgaaataaa
    73321 tccaaatgat ttaagaatag atgttttccg ttcttcaggt aatggaggac aaagtgtcaa
    73381 tactactgac tctgctgtta gggtaacaca tatacctaca ggtgaagtag tatcttgtca
    73441 agatggaaaa tcacaattaa aaaataaaga gcaagcttta aaaatattaa aagctagact
    73501 ttacgataaa gcattggcag aacaacacaa agatatagca gcagaaagaa aaagccaagt
    73561 cggaacagga gacaggtcag aaagaataag aacatataat ttccctcaag gtagaataag
    73621 tgaccataga ataaatttaa ctttatataa gttagatgca ttcttagatg gagatataga
    73681 tgaaatgata gatgctttaa ttactgttga ccaaacagaa aaaatgactg caatataagt
    73741 aatgttttaa agaagctgtt tcttcctaga aattattttc tattttgaaa cagctatttt
    73801 gcattttagg tcatgttatc atattctatt gtatataatt gttatataca agtataggag
    73861 ggttatatga tactaaaagt aacaataatt gggcttttgg caggtgttat agggacagga
    73921 ttaggaggag taatatcagc catttttaaa agagaggtcg ataaatatct aagttttttt
    73981 atgggattat ctggtggaat aatgttggct gtagtggtgt ttgatttaat gaaagaatcc
    74041 atggacaaaa tggggataat caatacagtt atatttacgt ttgttggagc tctcataact
    74101 atgtacataa aaacaaaatt agatgtgtct ggaaatatgg catctggata tcttatattc
    74161 ataagtatat tactacataa tttaccagaa ggactagcca ttggttcttc ttttatgtca
    74221 actgaaagtt taggtattac acttgctata gttataggtc tacataatat accagaaggg
    74281 ttagctatgg cattaggctt agtttgcaat aaaatgaaac taagtaaagt tattttgttt
    74341 actgtaatag ctggattacc tatgggtcta ggaagttttt taggtgttta ttttggagga
    74401 gtatttactt ctcttatagg agtatttctt gctacagcag gaggtactat gatgtatgtt
    74461 gtattggaag aaatttttcc acattcaaaa agtgtgtatt gtataattgg tttcttgtta
    74521 ggtacaatga ttgtaaatta tatataaaat taaaatgaaa gcaggcatac aaaagatgaa
    74581 aactattata agtaatattg atataaataa tattgattat gaggaaataa aaatacaagc
    74641 aaaacttctt agagaaggta aaacggttat ttttccaact gagacagtat atgggttggg
    74701 tgcaaatgca ttagatgaaa atgcagtaaa gaagatttat gaagctaaag gaagacctag
    74761 tgataatcca ttgatagtcc atatatatga aaaagaagaa gtatatgact tagccaaaga
    74821 tataagtgat aaagctaaac ttgttataga aaagctttgg ccaggaccta taacaattat
    74881 attaaataaa aaagatataa ttccatacaa aactagtgga gggcttgata cagttgcaat
    74941 aaggatgcct tctaatgtta ttgccagggc aataataaaa gaagctggta tacctattgc
    75001 agctccttct gcaaatatct caggtcgccc atctccaaca aaagcaaaac atgtatatga
    75061 agagatgaat ggaagagtgg atggaatagt tttaggagga gacagtaatt ttggattgga
    75121 gtcaactgta ttggatttaa cagaagagac tcctatgata ctgagaccag gaagtataac
    75181 taaagaagtt ttagaggaac ttcttggaga agtaaagctt gacccatcat taagtaaaaa
    75241 agaagataat caaaaagcta aagctcctgg aatgaaatat aaacattatt ctccaaatgc
    75301 agatgtatat ataatatctg gaaaaagaga aaatgtagca acaaagatta atgatatgat
    75361 aaaatctaat agagacaaag gtctaaagac aggtgtaatg tgtattagta gaaaccgaga
    75421 gttttatgat ggagaagtaa tcgatttagg aaactctctt gaagaagttg caagtaatct
    75481 gtttgatgct cttatagaaa tggacaaaaa gggtgttgat gtcatatatt cagaagagtt
    75541 ccccaagact ggagttggac aagcaattat gaatagacta ctgaagtcag caggatacaa
    75601 agtgataaag gcttaagagg gagttgtaaa atatgaatat acttattgtg tgtacaggta
    75661 atacttgtag aagccctatg gctgaggcta tactaaggaa agcaattaaa gaatctggaa
    75721 gaagtattga agaatattct atatcatcag caggtatatc tacagcaaat ggaatgggtg
    75781 cttctgaaaa ttctatagaa gtactaaaag aaatcggtat agacttatca aatcatagaa
    75841 gtaaagtaat tactaaaaaa ttaattgatg aatcagatat aatactaaca atgactaaat
    75901 ctcataaaga aattttagta caagcagttc caaaatgcaa agaaaaagtg tatactttta
    75961 aagggtttgc aaataaaaat gaggaagata tatctgaccc atttggtgga aatttggata
    76021 tttatagaag cactatgaga gaaataatgt attctgtcaa cgaaatagta aaaaaaatat
    76081 gaaacggagg ataaacaaat gaagatagga ttaggctgtg accatggagg atataattta
    76141 aaaaaagaaa taataagcta tttagaaagt aaaggtatag agtgtgtaga ttatggaact
    76201 aataatgcta cagattctgt tgattatcct gtttatggag aaatagttgc aaattcagtt
    76261 ataaataaag aagtagatta tggaatatta tgttgtggta cagggatagg aatatcttta
    76321 gctgctaata aggttcctgg gataagatgt gcagttgtat cagatgtatt ttctgcaaaa
    76381 atgtcaaaag cacataatga tgcaaatatg ttatcattag gcgaaagagt tttaggaaaa
    76441 ggtctagcac ttgagatagt tgaagcatgg attaatacgg attttgaagg tgatagacat
    76501 gctagaagag taaacatgat taaatcaata gaagaaaaac ataataaata ataaaaatta
    76561 cagttttatc aggaggaatt atcaaaatga gcaaagtggt agagacaaac catccattaa
    76621 tacaacataa attaacttta atgagagata aaaatactgg ttctaaagac tttagagagc
    76681 ttttaactga aattgcaatg ttaatggggt atgaaataac aaaagatata ccattaaaag
    76741 atgtagaaat agaaactcct attcaaaaaa catcatctaa agtagttgca ggtaaaaaat
    76801 tagcaataat tccaatttta agagcaggtc ttggaatggt agatggatta gtgagcttaa
    76861 tgccagcagc aaaagttgga catgtaggac tatatagaga cccagaaaca ttaaaaccag
    76921 ttgaatatta ttgtaagctt cctcaagaca taggagaaag agatataata gtagttgacc
    76981 ctatgcttgc aacagggggt tctgctgtag cagctataga tttacttaag tctaaaggag
    77041 ctaaaagtat aaaattagct aatttagtag ctgcaccaga aggtatagca gaagtgcaaa
    77101 aatatcatga tgatgttgat atatatgttg catcagttga cgaaagatta aatgaacatg
    77161 gatatataat tcctggtctt ggtgatgctg gagatagatt gtttggaact aaataaaaat
    77221 aaataactat aaatatttat tagggacttt cttatatagt gtatataatt ttatgtaaga
    77281 aggttctttt ttatatattt tttctcaaaa taggaattat tgaattgata aatttctcga
    77341 attgagaata aaaagttttt accaattaaa aaagattgct tattttacaa ggttttatag
    77401 aatagtagtc tattttaatg tggcatgtta gttgcttacg attataggta ttaagtgtat
    77461 tagttaaatt gagaattgaa tattaataat attattggga gtggtaatac atgaagaatt
    77521 gtatagtagt aagaggggct ggagatttag caacagcagt tattcataaa ttacacaaca
    77581 gtggttttaa agtagttgcg ttagaaatag aagagccatt agctataaga aggcaaattt
    77641 ctttttgtga ggctgtttat gaaaaaaaag taactgttga aggtgtagaa tgtatatttt
    77701 gcaatactga aaaagaaata gaggaagttt tatctcaaca taaagtagcc ttgattatag
    77761 acccaaaagg agaaaaatta tctaaattaa atccaatcgt tttggttgat ggaatactcg
    77821 ctaagaaaaa cttaggtaca actaaagata tggcaccact tacaatagct ttaggtcctg
    77881 gattttgtgc aggagaagat gtagatgttg ttatagagac aatgagaggt cataatctag
    77941 gaagaataat aactaatggt agagcagaaa aaaatacagg agtaccagga gcaataaaag
    78001 gtttttctaa agagagagtt atgcattcac agtatgatgg cataatggaa aatgtatgta
    78061 agataggtga tatagttgaa aagggagacc tactttgcta tattaataat tatgaaaaaa
    78121 aacatgaagt tagagcaaca atatctggag tccttagagg tttattaaag gatggagcaa
    78181 aggtaaacaa aaatttaaaa atactagaca tagaccctag aaaagaagaa gttaagaatg
    78241 cttttacaat atcagataaa gctagatgta tagctggagg ggttttagaa gccatactaa
    78301 acaatgggat ttatccccaa aattaattta tattagataa agctattaat attttattaa
    78361 gatgatataa taaatttaat agattaaaga gagcatatga cgggtattta aaatttaaat
    78421 ggtaaaaatg ctcttttttt attggacatt caattaacat gtgtatataa tataaaaata
    78481 agtatttatt taggttgaaa tctaataaat atataatacc agtacataag caaagaggag
    78541 aaaagtaaat tatgagacca tcatgggatg aatacttcat ggaaattgca gaagtagtga
    78601 aaaagcgttc aacttgtatt agaagacaag taggagctgt aattgtaaga gacaaacaaa
    78661 tattaacaac tggatataat ggttctccga gaaatcttga acactgtgaa aatattggat
    78721 gtaagaggca ggaattaaat attccctcag gagaaaggca tgaattatgt agagcattac
    78781 atgctgaaca aaatgcgata atacaagctg ctcataatgg tattagtgta gatggggcaa
    78841 ctttgtatgt tactacaaga ccttgtgttt tgtgtgcaaa aatgtgcata aatgcaggta
    78901 tattgaaaat tgtttatgaa ggtgattatc cagatgatat gtctacagaa ttattaaaag
    78961 aagcaggaat agaactcata aaattttagt ggataaaatt tatatgacaa taaatgtcaa
    79021 attatgacac tgaaatacaa tggtatcaaa tgattaaaag aaagtatttg aaaaatcatc
    79081 agattagtag taagatatat tttataatta aataaattta tgagatagat taattacatg
    79141 ttatttattt tataataatg agggatacta tttatgagta aaagaaatac acatacagaa
    79201 attgcaaagt tgtttagttt aataagtcaa ataggattga tgattgtaat atcaatatta
    79261 ggatgtactt tcttaggaaa atttttagat agtaaattga atactactcc agttctgaca
    79321 ataatatttt tattgttggg tgttggaggt gcttttagtg gtgtttataa aactctaata
    79381 gtatatacac gaaggaagtg atatattgga tataaaatta cttaaccagg taaggtcagt
    79441 aacaaaaggt atagtaatat ttgatgtagt tttaattgtg ctaatgttga taacatcaac
    79501 attaagtaaa ccagtattat taggacttat atttggctct ataatagcta tgttaaattt
    79561 tagattattg gcgatatcac tggaaaaatc agtgacattt cctgctggga aggcacaagc
    79621 ttatgcatca gcacaatatg ctgttagatt atttataatg gcagttgttc taattgcatc
    79681 agctacagta ccacatttaa atataatcgg aacagcattg ggattattga gcacaaagtt
    79741 tgtcatatta tcaaaaaact ttataaataa attaaagagg aaggaggcat aagtatgaat
    79801 caagcgcatt attatctcat aggaaacttt aagattagtg aaacaatact agtaagttgg
    79861 ggaataatgg cctttttagc gatagcatct tattttttga ctagaaactt aaaaaaagtt
    79921 ccaactagta aagttcaaat attcttagaa tttgcagtag gtggtcttgc taaaatggtt
    79981 acagatgtta tgggtaaaaa tacagtaaaa agaatgccat atatgatacc atacatagga
    80041 agcttgtttt tatttttcgc atgttcaaat ttaagcccat tacttggatt aaggtcacca
    80101 acaaccgact tagacacaac tgctgcatgg gcaatgatta cattttttat gatttatttt
    80161 gcaggagtta aatttaaggg gttatcatac tttaaagaat tggctcaacc acttgccata
    80221 atgttaccaa tcaatattat aggtgagtta gctagaccaa tatcattaag tttccgtcca
    80281 tttgggaata ttttaggtgg aacaataata atgggtctgt tttatcaact tttaggtttt
    80341 atatctagtt taataccagg attatcaata ccaattggag aaatattaat accagtccca
    80401 ttacacttgt actttgactt atttgcagga ttgttacaag catatatatt tataatgtta
    80461 acaatggtat ttatatcaag tgcaggagag ttagattaag aaatcaactt atattaagat
    80521 aaaaataaaa taatttaaaa aattaaagtt ttaaggagga aataattatg gaaacagcaa
    80581 tagtagcggc agcatcagca ataggagcag ggatagcagt tgcaacaggt ataggtgcag
    80641 gtataggtca aggtatagca gcagctaaag ctgcagaagc agtaggaaac caaccagaag
    80701 ctaaaggtga tataacatca actttattac taggagttgc tatagcagag tcttcagcaa
    80761 tatatggttt ggttatatca ataatacttc tattcgtaaa tccattcttt aaatacttag
    80821 gaatgtagat ttagtcctta aatattttga gataggttta taggtaaatc atctcaaact
    80881 tataatcatg agatgaactt tatcatctcg tgattataag tagttatgat ttatggaaag
    80941 gaggataatt atggaaaaag cactagtagg tataacgtgg gaatttgtgt tccaaattgt
    81001 taatactttt ataatatttt tacttctgag aaagctttta ttcaagccag tattaaatat
    81061 aattgaatca agagaaaatg atattaaaag tgatttggca gaaggcgaaa aagcaaaaaa
    81121 tgaaggttta gctctgaaaa aagaatatga gtcaaaaatc aattttgcca aggatgaagg
    81181 tcaagaaatc ataaaacaag caactataag agcagagcag aaatcagatg atatagtaaa
    81241 tactgcaaag aaagatgctc ttgatataaa agaaaaagca aacaaagata tagaacaaga
    81301 aagacaaaag gttataaatg aaatcaaaaa tgatatatct aacatagcac tacttgcagc
    81361 atctaaagtc attgaaaaag atttagataa atctaaacat gaagaattga tagaaaactt
    81421 tataaaagag gtaggggaag ctaaatgata aatgtaatag caaatagata tgcagaagcc
    81481 ctatttcaat taggagaaga agaaaattca actgatgtct tattcaaaga actagaaaaa
    81541 gtagtagata tgatgactaa agttagtaaa gatttctaca aagttttaaa atcaccatta
    81601 gtttcaaaat cagaaaagaa aaacttggta gaaattattt ttagtaaaga agtaagttct
    81661 aacataaaaa actttttaaa agttttagta gataaagata gaatatcata tttagaagat
    81721 atcgaattag cttataaaga attattaaat aagaaaaaca atgtaattga tggagtagca
    81781 ataagtgcta ttccaatgag tgaaacagat attaaagaac ttgaagtcaa actttcaaat
    81841 aaatacaaca aaaatgttac tatagaaaat gttgttgaca agactatact agggggagtt
    81901 ctagttagaa ttggaaatga acaaatagat ggcactgtga aaactcgtct tgataagatg
    81961 aaagaaaagc tatctgaagt aatatcttaa gaatggcggt gaacccatga acttaaaacc
    82021 tgaagaaata agttctataa ttaaacagca aataaaaaat tatgagaata aagttgagtt
    82081 gacagataca ggtagtgttt taacagttgg ggatggtata gcgagtgtat atggattaga
    82141 aaaagctatg tctggtgagt tgctagagtt cccaggtgaa atatatggta tggcacttaa
    82201 cttggaagaa gaagtagttg gagctgttat ccttggagat gacagtgaaa taaaagaagg
    82261 cgatatagtt aagagaactg gaagaatagt tgaagttcca gttggagaag ctttaatagg
    82321 tagagttgta aactcactag gtcagccaat agatggaaaa ggacctatag cgtacacaaa
    82381 aactagacca gttgaatctg aggcacctgg tataatagat agaaggtctg tttatgaacc
    82441 attacaaaca ggaatcaaat caatagattc aatgatacca attggtagag gtcaaagaga
    82501 gttaataata ggtgacagac aaactggtaa aacatctata gttattgaca ctatactaaa
    82561 tcaaaaagga aaagatgtta tctgtatata tgtagcaatt ggacaaaaac gttctactat
    82621 agctcaatta gttagctctt tagaaaaagg tggagctttg gattatacaa tagtagtttc
    82681 agcaacagca tctgaatcag caccacttca atatatagca ccatatgctg gagcagctat
    82741 gggtgaagaa tttatgtaca atgggaaaca tgtacttata gtgtatgatg atttaagtaa
    82801 acaagctgtt gcatatagag aaatgtcatt gttacttaga agaccaccag gacgtgaggc
    82861 atatcctgga gatgtattct atttacattc aagattactt gaaagagcag ctaagttatc
    82921 tgatgaattg ggtggaggtt caatgactgc cttgcctata atagaaactc aagctggtga
    82981 cgtttctgca tatataccaa caaatgttat atctataaca gatggtcaaa tatacttaca
    83041 accagagtta ttctattcag gtgtaagacc agcagttgac cctggtatat cagtatcaag
    83101 ggttggtggt tctgcgcaaa ttaaagcaat gaaaaaagtt gcaggaacat taaaacttgc
    83161 atattcacaa tatagagaac ttgcagcatt ctcacagttt ggttctgact tagatgaaga
    83221 tactaaaaag agacttgctc aaggtgaaag aatcgttgag atattaaaac aaggtgagca
    83281 tcaaccaata aaagttgaaa atcaagttat gataatatat gctgttataa ataatcattt
    83341 agaggatatt ccgatagata atatagctag atttgaatca gaattgtatg catttgtaga
    83401 taataattat ccggaaatat caagaaaaat attaggtgga gaagacttca ctcatgattt
    83461 aacagatgca ataaatgaat ttaaagaaaa gtttgttgtt gaagtataat cctttttaaa
    83521 aaaggaggta aattaattgg caggagctgg aatcaaagca atcaaaacac gtatgggaac
    83581 tgttgaaagt acaaagcaaa taactaaagc aatggaatta gttgcatctt ctaagcttag
    83641 aaaagcaaaa gaaaaggctg aagattcaag agaatatttt aatactttat acaatacagt
    83701 aaaagatatt gcccaaacaa cacgtggaat tagaaatgaa tttttaaaag aaagagaagt
    83761 aaaaaataaa tgctatgtag tagtagctgg agacagagga cttgcaggtg gatacaattc
    83821 taatgtatta aaggaatctg tctctcatat gaaaggtaaa aaggaaacag tgattactgt
    83881 tggaaagaaa gcacatgaat ttttttctaa aagaaactac aatatagcaa aagatataaa
    83941 tagtgttgaa gcttgtggat atgaagatgc gacagaaatt tcacaaacta ttattgacct
    84001 gtataaaaaa ggtgaagtag atgaagttta tattgcttat acaaaattta aatctgcttt
    84061 atcacaagaa gttgaaattt tgaaattgct tccattagtc tttgaaaaag atacagacga
    84121 acaaggaatg gcagtaaaag aagaaaaaca aaatagatca aaagtacaat atataccatc
    84181 agcagaagca gttttaagtt atattgtacc tcagtttata tcaggtacag tatatggtgg
    84241 aattttggaa tcttttgcat cagagcaagg tgctagaaga actgcaatgg aatcagccac
    84301 agacaatgcg aatgaaatgc tatctaattt agagttaagt tataacagag caagacagtc
    84361 agctgtaact caagaaataa cagagatagt tggtggagtt gaagctctaa aatagggagg
    84421 ttaggaaatg gcaaatgtag gtaaagtagt acagattgta ggagctgtac tagatgttaa
    84481 gtttgatagt gaacaaagcc tacctaactt attaaatgcg ttagtaataa agttaggaga
    84541 taaagaaata gttgcagaag ttgctcaaca tataggtgat gatactgtaa gatgtatagc
    84601 tatgagtgca acagacggac ttgtaagagg tatggaagtt gtagatacag gagggccaat
    84661 aagtgttcct gttggagatg aaactttagg tagaatattc aatgttcttg gaaaaccagt
    84721 tgatgggaaa ccagctccaa aatctgcacc taaattacct atacatagac cagcaccagc
    84781 atatgatgaa ctagaaacta cagcagagat actagaaact ggtattaagg tagttgactt
    84841 actagctcca tatctaaaag gtggaaaaat aggtctattt ggaggagcag gagtaggaaa
    84901 gacagttcta atacaagagc ttataaacaa tattgctaag caacatggtg gtatttctgt
    84961 gttttcagga gtaggagaaa gaacaagaga aggtaacgac ctttatggcg aaatgagtga
    85021 gtctggagtt ataaataaaa cagctctagt atttggtcaa atgaatgaac cacctggagc
    85081 gagaatgaga gttgctttaa ctggacttac aatggcagaa cattttagag atgagcaagg
    85141 acaagacgtt ttacttttcg ttgataatat attccgtttc acacaagctg gttcagaagt
    85201 ttcagcactt ctaggacgta tgccatcagc tgttggttat cagccaacat tagctactga
    85261 aatgggtgca cttcaagaga gaataacatc aactaagaaa ggttcaataa catctgttca
    85321 agcagtatat gtaccagcag atgacttaac tgacccagca ccagctacaa cattctctca
    85381 cttagatgca aaaacagttt tatcaagaca aatatcatca ctgggtatat atccagcagt
    85441 tgaccctctt gaatctacat caaggattct tgaccctagt atagtaggaa aagaacatta
    85501 tgaagtagct agaggtgtac aatcaatact tcaaagatat aaagaacttc aagatataat
    85561 tgctatactt ggtatggatg aattatctga tgaagataag ttaatagttg cacgtgctag
    85621 aaagatacaa agattcttat ctcaatcatt cacagttgct gagcaattta caggaaatcc
    85681 aggtcaatat gttcctgtta aagagactgt aagaggattt aaagaaattc ttgaagggaa
    85741 acatgatgac ttaccagagt cagcattctt atttgtagga acaatagaag acgctgttag
    85801 aaaagcgaag ggaagtatgt agtcatggcc agtgaatttt cattgaaagt tgtaactcca
    85861 agtaatactt tttatgatgg agatgttgaa atgatagtag ttagaactac aaaaggagac
    85921 aaaggggtgt tgaaaggtca tataccattt gtttcaggta tacctgtagg aactttaaag
    85981 ataaaaaaag agggaagttt taaagaggcg aaaatagcag aaggattcat taatgtaact
    86041 caagataaaa ctgtcatatt gacagaatct gctgagtgga tttaataaat taatttagag
    86101 tataaaaagt cattttgacc aaaaaaactt ttgggtaaaa tggctttttt gcgttttggt
    86161 gttaataaaa taacgataaa attgtaagtt tttagtgata ataaattcac aaaatgttta
    86221 aatttactgc caaattatgt tgtaattaat aagataaaga agatttagat agcttttatg
    86281 taagtgaaaa agtcttcata taagaaatac atataaaatt tttataaaat ttaa
//
LOCUS       DAYAOO010000005        76266 bp    DNA     linear   BCT 12-OCT-2024
DEFINITION  TPA_asm: Clostridioides difficile isolate ST8-SSI-h139-18
            SAMN40601845-rid21577343.denovo.005, whole genome shotgun sequence.
ACCESSION   DAYAOO010000005 DAYAOO010000000
VERSION     DAYAOO010000005.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN40601845
            Sequence Read Archive: SRR28438827
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 76266)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 76266)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-MAY-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-MAY-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002157583.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002157583.1
            Genome Coverage       :: 163x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/11/2024 16:19:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 4,038
            CDSs (total)                      :: 3,963
            Genes (coding)                    :: 3,930
            CDSs (with protein)               :: 3,930
            Genes (RNA)                       :: 75
            rRNAs                             :: 6, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 60
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 33
            CDSs (without protein)            :: 33
            Pseudo Genes (ambiguous residues) :: 0 of 33
            Pseudo Genes (frameshifted)       :: 7 of 33
            Pseudo Genes (incomplete)         :: 25 of 33
            Pseudo Genes (internal stop)      :: 11 of 33
            Pseudo Genes (multiple problems)  :: 8 of 33
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..76266
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN40601845-rid21577343.denovo.005"
                     /isolate="ST8-SSI-h139-18"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Denmark"
                     /collection_date="2018"
                     /collected_by="Statens Serum Institute"
     gene            complement(208..1785)
                     /locus_tag="ACGI5H_000420"
     CDS             complement(208..1785)
                     /locus_tag="ACGI5H_000420"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861679.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall-binding protein Cwp5"
                     /protein_id="HFG9696152.1"
                     /translation="MKAPKTILTILTIALTLSSISIIPSYALTEEKLIGNGRYETAVK
                     ISQKAYSSSPNVVLVNDNSLADALSATPFAKAKGAPILLTESDKLDDRTEKEIKRLGA
                     KDIYLIGGTAVLNKDIENKLKSNGLNVERINGKDRYETSLILANKLKDIKDIKEVAVV
                     NGEKGLSDAVSVGAPAAQNKMPIILSSPKDGVEAFDKFIRDEKVIKAYVIGGTNSVSR
                     AVEKSLPNAERVSGKDRNETNAKVIEKFYTDTNLSNLYVTKDGSKNENQLIDSLAVGV
                     LAAKNESPVVLVGNKLNTKQRDILSTKKLNTITQVGGNGNEEAFDEIKSLQEKTVFEA
                     KTVEELTDMINIASPNDIINFKPKENTVNEAFRMVTNKPITVNIKGDCSKTLTVDMPN
                     GEVNNYATLVNVIVRNIGEGGFNNHDTITILSVRDKNGRVIENTRNSDIDTLMILASA
                     NDTKLINDGYIGKLIDNSSNSDITNNGTIDKKVNQVEDLEAKVDSIEKAIDSISQKVN
                     KIQDILDKLGFLKKFLS"
     gene            complement(2082..4493)
                     /locus_tag="ACGI5H_000421"
     CDS             complement(2082..4493)
                     /locus_tag="ACGI5H_000421"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861680.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall-binding repeat-containing protein"
                     /protein_id="HFG9696153.1"
                     /translation="MRKYKLKKLSKLLVLLTVCFLIVSTIPVSAEKNKILTGVETAEY
                     SESYLQYLEDVKNGDIAKYNGVIPTPYEMEGTTLKTNVRSSLPASYKSSVSYDPRKLD
                     LTTPAKDQGKLNTCWAFSGMSTLEAYLKLKGYGTYDLSEEHFRWWSTGGIHGWNLTDM
                     TGSSNVTAIGYLTAWAGPKLEKDIPYNFKSEDEGATRPQNMDTAPTQFNVTDVVRISK
                     DKTSVKNAIMQYGAVTSGYAHYSAYLSDDENSYNCNDKSEPLNHSVSIVGWDDNYSKD
                     KFKPSVRPESNGAWLVKSSWGEFNSEKGFFWISYEDKTLLKDTDNYAMKSVSKPDSDK
                     KMYQLEYAGLSKIMSNKVTAANVFDFSRDSEKLDSVMFETDSVGAKYEVYYAPVVNGV
                     PQNNSMTKLASGTVSYSGYINVPTNSYSLPKGKGAIVVVIDNTANPNREKSTLAYETD
                     IDGYYLYEAKANLGESYILQNNKFEDINTYSEFSPCNFVIKAITKTSSGQATSGESLT
                     GADRYETAVKVSQKGWTSSQNAVLVNGDAIVDALTATPFTAAIDSPILLTGKDNLDSK
                     TKAELQRLGTKKVYLIGGENSLSKNVQTQLSNMGISVERISGSDRYKTSISLAQKLNS
                     IKSVSQVAVANGVNGLADAISVGAAAADNNMPIILTNEKSELQGADEFLNSSKITKSY
                     IIGGTATLSSNLESKLSNPTRLAGSNRNETNAKIIDKFYPSSDLKYAFVVKDGSKSQG
                     DLIDGLAVGALGAKTDSPVVLVGNKLDESQKNVLKSKKIETPIRVGGNGNENAFNELN
                     TLLGK"
     gene            4668..5084
                     /locus_tag="ACGI5H_000422"
     CDS             4668..5084
                     /locus_tag="ACGI5H_000422"
                     /inference="COORDINATES: protein motif:HMM:NF016060.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_process: GO:0000271 - polysaccharide biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GtrA family protein"
                     /protein_id="HFG9696154.1"
                     /translation="MEENFLILKKHLETILYLFFGALTVLINIITYLFFTRIINFTFL
                     LSNSLSWSIAVLFSYITNKFFVFKSEKTEFLFLLKEFVSFLSCRLFSGFIEILLMYLM
                     IDLFSLNDILVKIGTNIIVIILNFVFSKVVVFKHRN"
     gene            complement(5149..7266)
                     /locus_tag="ACGI5H_000423"
     CDS             complement(5149..7266)
                     /locus_tag="ACGI5H_000423"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728928.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall-binding repeat-containing protein"
                     /protein_id="HFG9696155.1"
                     /translation="MQISKKIISLLTAAFLSIVLPSNVVNASNKDSLIGSGRWETAIK
                     ISQNGWLRSDNAVLVNDNSIADALSATPFAKLKDAPILLSGSKELDFRTKSELKRLGV
                     KNVFLVGGSNALGVNVENELKSEKITVERIFGNDRYETSLKLAEKLNNEKDISDIIVV
                     NGEKGLADAVSVGSIAAQNYMPIILSDSNLGVEVANKFIKAQNIKNSYIIGGLNSISN
                     EIEKNLPNSKRISGNNRNETNANVIKEFYKETDLRNAYITKDGMKKQSDLIDSLSVGV
                     LAAKNNSPVVLVGNKIDSIQKDVLNTKIFSTVTQVGGIGNENVYKDILDMQEETKYTV
                     ETIEELDSALKKVDANDIIKFRPDKKISESFKLETEKAIKVDLYGEYSQSITINMPNG
                     ELNNTGDISKTLILKDIKDGTLTNSGYINQMDISDDNGCKIENENNGQIWIVTIFSSA
                     KDVNIRNDGTITKIDNDSSSTNIRNSGKIDTVSGNKEPGISGNKPNTNNTDKDDDSDT
                     AAGLSPKISACSPLENNQIMLTVPQKPKNSNYKIYYRVLSYKPSAMRVGDRININDWD
                     LVEDTEPLKVNAKNGSYIEVVEIDYTRKKVSRWGRAGATDDGFKIVANGIKSTVSVDE
                     NSKVTISVTGYNGNKVYYRIKTTKPEAMNVGDEIDSSWKSTSNSDIILEGNKVNGLYV
                     ELASGENNKVEKWGATDKIEIVS"
     gene            complement(7297..8004)
                     /locus_tag="ACGI5H_000424"
     CDS             complement(7297..8004)
                     /locus_tag="ACGI5H_000424"
                     /EC_number="3.5.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422831.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0019213 - deacetylase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PIG-L family deacetylase"
                     /protein_id="HFG9696156.1"
                     /translation="MVDATLFFTPHQDDETLSMGSAIIEHVEKSDTHVILCTDGSKSI
                     IRKVLDDGGSCSYHIKDVHKYSLSESEFSKDRDEEFKDSCEAMGVKESNIHIEDNRAH
                     DGELSKEKAKEIILKYLEEYPEAKVKTVTPFKASGIHEDHRALGEAALELYREGKIKD
                     LRFYVEPYDYKDFKKVNPNVEVWKVLPSQEEKLLSAMNAYKKWNPESGHYAIGYHSVK
                     SHFDDLELNKTQYVHAP"
     gene            complement(8111..9982)
                     /locus_tag="ACGI5H_000425"
     CDS             complement(8111..9982)
                     /locus_tag="ACGI5H_000425"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861684.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall-binding protein Cwp2"
                     /protein_id="HFG9696157.1"
                     /translation="MNKKNLSVIMAAAMISTSVAPVFAAETTQVKKETITKKEATELV
                     SKVRGLMSQKYTGGSQVGQPIYEIKVGETLSKLKIITNIDELEKLVNALGENKELIVT
                     ITDKGHITNSANEVVAEATEKYENSADLSAEANSITEKAKTETNGIYKVADVKASYDS
                     AKDKLVITLRDKTETVTSKTIYVGIGDEKVDLTANPVDSTGTNLDPSAEGFRVNKIDK
                     LGVAGAKNIDDVQLAEITIKNSDLNTVSPQDLYDGYRLTVKGNMVANGTSKSISDISA
                     KDSETGKYKFTIKYTDASGKATELTVESTNEKDLKDAKAALEGNSKVKLIAGDDRYAT
                     AVAIAKQTKYTDNIVIVNSNKLVDGLAATPLAQSKKAPILLASDNEIPKVTLDYIKDI
                     IKKSPSAKIYIVGGESAVSNTAKKQLESVTKNVERLAGDDRHMTSVAVAKAMGSFKDA
                     FVVGAKGEADAMSIAAKAAELKAPIIVNGWNDLSADAIKLMDGKEIGIVGGSNNVSSQ
                     IENQLADIDKDRKVQRVEGETRHDTNAKVIETYYGKLDKLYIAKDGYGNNGMLVDALA
                     AGPLAAGKGPILLAKTDITDSQKNALSKKLNLGAEVTQIGNGVELTVIQKIAKILGW"
     gene            complement(10326..12671)
                     /gene="secA"
                     /locus_tag="ACGI5H_000426"
     CDS             complement(10326..12671)
                     /gene="secA"
                     /locus_tag="ACGI5H_000426"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891056.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006605 - protein targeting [Evidence IEA];
                     GO_process: GO:0006886 - intracellular protein transport
                     [Evidence IEA];
                     GO_process: GO:0017038 - protein import [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecA"
                     /protein_id="HFG9696158.1"
                     /translation="MSVLDTILDKADEQEIRRLNVIVDKIESLEKDIENMSDDELKKM
                     TDLFRDRLKKGETLDSLLPEAFAVAREASKRVLGMRQYRVQLIGGIVIHQGKIAEMKT
                     GEGKTLVEVAPVYLNALTGKGVHVVTVNDYLAQRDKELMQPVYEFLGMSVGVIIADLI
                     PEVRKVQYNCDITYGTNNEFGFDYLKDNMVTKKFDKVQRELNFAIVDEVDSILIDEAR
                     TPLIIAGEGDEDSKLYELANSFIKTIKEEDYELDRKDKTVALKESGIDKAESFFGIKN
                     LTDIENIELYHHINQALRGHKLMEKDVDYVVVNQEVMIVDEFTGRVMDGRRYTDGLHQ
                     AIEAKEGVEIKDESKTMATITFQNFFRLYNKLSGMTGTAKTEEGEFESIYKLNVVQIP
                     TNKPIIRADLHDKVFRTEKEKYQAVVEEVIRIHKTKQPILIGTVSVEKSEMLSGMLKK
                     EGIKHQVLNAKENDKEALIVSKAGKLGSVTIATNMAGRGTDIALGAGDKEEESRVKEL
                     GGLYVIGTERHESRRIDNQLRGRSGRQGDPGTSRFFVSLEDDVIKLYGGKSIEKLMKR
                     PNSNKNNSIESKSLTKAIERAQKGVEGKNFELRKNVLKYDDTINEQRKVIYNERNKVL
                     NDEDIQVDIQNMVKDIIKEAAAEYLTKRKRDYYGYFKHLYNTFMPADTLLIPDLDNKS
                     IEDIIDSTYEISKRVYDLKKMVVGLDKITEMEKIVLLKVVDQYWVEHIDAMEQLKQYV
                     GFKSYAQKDPFKEYAMEGYEMFESLNKNIRETTIQYLYKFN"
     gene            complement(12907..15087)
                     /gene="slpA"
                     /locus_tag="ACGI5H_000427"
     CDS             complement(12907..15087)
                     /gene="slpA"
                     /locus_tag="ACGI5H_000427"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728932.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S-layer protein SlpA"
                     /protein_id="HFG9696159.1"
                     /translation="MNKKNLAVVMSAVTVIGSAAPVFAAAEDSFPNGNTTVSSSKYSD
                     IERILKKYVADGVTGITVNFFDKKGNPKGVSISSLEASQISYVKDEIKDLKAGEYAKI
                     SVKITDGTEKKYDDTLLKELDSNAVVTKVGTATTVKIVDQDGNSIENDAKLKLQKYDT
                     TTSAYVDGATKDEVLAATKAAVKTSKFTDKTGNNATGTVAITATYADAVAGAIKLKYD
                     TQAAVAPTLDTAVASLDGTKEIYDFSKPVITVNTTDGTSKLSFEKTGEKVGAVESNVT
                     VIAASDETVTISGDAKEKAEALAKKYVFKDTELEDAYKTVTASDFEKTDNDYYEVVLY
                     PTGKRLNTASTYASSNYKPELPTSDRVDTPAIITLRSTNKNNLKSALDELRTYNNSYS
                     NNSVLAGDDRIETAIEISKDSYNADGGIKGDYVEANEVVLVGSQSIVDGLVASPLAAV
                     KDAPLLLTSKDKLDSSVKSEIKRVMGLDDKTGITSKKTVYIAGGENSVSKEVANELKD
                     MGLKVERLSGDDRYATSLEIADEIGLNHNKVFVVGGTGLADAMSIASVASNKEMPIVV
                     VDGKGKDLSTDAKDFIGSAYVDIIGGKSSVSEDMEDAIDDATGKSPERVSGDDRQDTN
                     AEVIKTYFEKDNSDSVISTGVKNFYVAKDGSTKEDQLVDALAIAAVAGHNEAPIVLAT
                     DSLSSDQSVAISKVTNSDDSKKLTQVGKGIADSVIKRIKDLLEL"
     gene            complement(15380..16978)
                     /locus_tag="ACGI5H_000428"
     CDS             complement(15380..16978)
                     /locus_tag="ACGI5H_000428"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454089.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall-binding repeat-containing protein"
                     /protein_id="HFG9696160.1"
                     /translation="MKVNKRVLSIGLTISLIMAGAPNINALSSIEKIQGKDRYETSAL
                     IADKQIYDTVILVNTDNSIVDGLSASGLSGVVKAPIMLVQRDKIPTDVEKRLKDVKNA
                     YVIGTEDTIGKSVENQLKNKGIEVKRIGGEDRIKTSYLIAKEISAIKPVNDGDKVFLV
                     NGYTGEADAMSVSSVAARDGVPVILTDGKSIPFKVDGVQCYSLGSEEIMSNELVSKTN
                     SVRIAGKDRFETNKKVIQRFYKGTKKFYVSQGYKLVDAVAGSPLAKDKPIVLVNDGSD
                     KSVLRGADEVTSLGGMDKKVADQCISSASDKNTMPTITANDVEISVGDKFDNSMLNIV
                     ATDYYGNNLKPNIEGTVDTSKAGTYVLNVSAFDNFGQKCEINVNVKVIINTSTKDPNS
                     YEFKAMVSNEMYNLVNSYRKEKGKKSLRELDSLAGMANAWSKYMDEKKIFAHEIDGKN
                     AAEVFSGFGMRTDENIAYLPMNVKSVYTSKDAKEIAKSVFDLWKKSSKYNDNMLKEEF
                     YSFGFGMYVSNQREVNATMEFLNS"
     gene            complement(17197..18798)
                     /locus_tag="ACGI5H_000429"
     CDS             complement(17197..18798)
                     /locus_tag="ACGI5H_000429"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861688.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall-binding protein Cwp11"
                     /protein_id="HFG9696161.1"
                     /translation="MKMNKKILSLGLAVSLILVNFKSVNASSVVEKIYGKDRYETAAK
                     IADKQTYETVILVNTEKSLADGLSASGLSGATKAPILFTQQNKIPADTNRCLKNIKKA
                     YIIGTEDTISKSVEKELDSKNIEVKRIGGEDRLKTSYLIAKEIATIKKVDKVLLTNAY
                     SGEADAMSVSSVATRDGAPIILTDGKSVPFDVKNIQSYCIGSEEIMSNPLVKNTNSVR
                     IEGTDRFETNKNVIDYFFNSADGFYVSDGYQLVDAIAAAPLTKNSPMVLVNDGSDKTV
                     LEGAKNITSVGEIDEKVIQQCISASKSNGQPPAITVGSTEVYKGEKFDTGKLNIVAKD
                     NTGKVLPIEVDGFIDTNRVGTYILTLKATDEWGKSTGKRVEIKVLDDKSHDYNSPEFK
                     KMVSTEMYNLINSYRKEKGKEPLVVSSKLEGMANAWSKYMMDNKVFEHYIDGKNAPQV
                     FSEFGMRSEENIAYIYIDSKSVQTTQDAKDLAKAIFEVWKKSPEYNANMLSDEFYSTG
                     FGLYILSDGQVHATQEFLNGNEGSL"
     gene            complement(19165..21045)
                     /locus_tag="ACGI5H_000430"
     CDS             complement(19165..21045)
                     /locus_tag="ACGI5H_000430"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861689.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall-binding protein Cwp10"
                     /protein_id="HFG9696162.1"
                     /translation="MSKRKSFIRTIAVSTMAVAVTGSATCAYAAPVLQGTKTYEKVNT
                     IDISVDSVENIVYSFQASIKVQGEVEVVDNEQKEKITWSDNIKSQIKSGNANATCRAE
                     YNKSSNTTTLDIYVTSNEDLLDGNRLNIGRISVKKSGSNSNADYKVLGKGTNDKPALK
                     IVTYNNKTVDYENISSDEGLIFTLINESEVKPIGGTGSSKNDPEKYKVEKSEALEYLL
                     NNIRINYSIVSKETQESGSNVILKLGLAQKTTKGRKVTINKYVEVTLPKSLEYIVENE
                     LSKPDELPPDNGSGGNNGGGSNSGGSSSGGSSGGGNSSDSTSNVTVKKLKGDDRFETA
                     IKISQSGWTKSDTVVIVNGEDKSMVDGLTATPLASVKNSPILLSSNDKLPQKTVEELK
                     RLNPSKVVVIGGNNSMPNSVVEAIKAVNSKISVQRIGGDTRYQTSINIAKEIDKTNNV
                     SKLYIGAGNGEADSLSIASLAGKEKTPIVLTQKDGVDNEAEQFIKSNKVSNIYFIGGV
                     EKISNKAIEQVGKIANKDISNNRVAGQTRQETNAKVIDKFYSQSKLDGVVVANQDKLI
                     DALAVGPLAAKNNSPVILATNTLDKSQESSLKGKNSSKLFEVGGGIASSVIDKIKSLI
                     EK"
     gene            complement(21255..27218)
                     /locus_tag="ACGI5H_000431"
     CDS             complement(21255..27218)
                     /locus_tag="ACGI5H_000431"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903330.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M60 family metallopeptidase"
                     /protein_id="HFG9696163.1"
                     /translation="MKKAISCVLAVSMCSAPLNVFAEPILEGKLRAVEKSVTEKLRGS
                     LEVDLNFSLPIKNSDSESMTNMQLRLKDDSNNSGIIKLGEKDSGTVNVGTDNIEYTIK
                     KLSASRSEIKNKDENISYYNIVFNNLPVGKYNVEVSGDGFKNKEIKDIDISSYSQRVL
                     LSNRASVDNKNKPLNYELFLMGDVNGDGKVDKSDYNKVLENIDSNKREFDLNRDGKVD
                     IVDLDYVQKNLGQSEDAKSLESIVSTNPIVDTSKVELKGNSDVDINGNVENLFSGENN
                     GVTISSKNDEISEEKPAVMDIALSEALNMEVINIKAPEGTAPAKGIVEVTDKDGNVQQ
                     IPYENKEYMKNLKDEEQQEEVNNEQEEVNQEEVNNKDENINQTDNNSNNKDENNDEQQ
                     ENSDKQEVNSNTNQDKNNDKENSSMDKPNSDEDTPKEEGNISKDDNSTTSTYSKSTLE
                     TYADVQNSDIVINLGKQVAVKKITIKITATTANDRNLAEISKVEFLNNVYKEIPKPEM
                     NIPKINKISTSTAVGNEKVSFYWNNEVNVSAYELILDKIDSKGKVLSTKKLQTSKNTI
                     EVRDIEAYGLYRVSIQSLNGDWSSGYKDATPENLDGVPENVDSNYKPIQFSPDSILEF
                     QVVPDTKPEPPEGINVKGKFKSLDVSWKNHKQAKDFDLYYKEKGSNGSWIKYNDKLIR
                     GTSSKIEGLKDNTTYEVRMTATNHLGTSGMSKTYIGTTESMDAPTTPNYRLINTPKEN
                     GGFGIPTNHIVDVTYPAGYDKSEYSDKNPFDKFNVVDGDFTTHWTFPTYNAAEGTNRG
                     PIITFDKSYTMDTFMATPRFDVSDKTINDFEVRYWDENGQLHNLGDVPFETKTDPVNN
                     NKYVMVRLKEPITATKIQVSVCSSYSYKSNISELKFYEYDSIEDDVRNLFMDDLQVEL
                     KEDVTQEKITELKDRLNTPDKASGEYHPYKTVIERELKLAQDLYNDRATLTDVTTVNQ
                     EINKLGKYKDKNGQYTVNSNNLGMQNDWQALGVAARAGDEITVYVGSKSGKTPKLIYT
                     QYYGESGAYKSGEINLNTGKNVIQLSKLHSLDIECGGSLYIRYAEDTPSGGDIKVRVA
                     GATKIPHLNLNGTINDKSPAGVSESKKKIKAYIEELARYKDAVKGEPYYPGTNVGNSY
                     GYSEKTGVLNTTDIESDKVTLNVPATAVYQGISKGNADLNTQVDRLYNSMLAWEQIMD
                     LVYSERGVFKTQDLDGNGTVDDNEFNLTKNDMAPKSRMNIKYQRMFIGAFMYASGLHV
                     GVEYGSVPGLMNGVPFQIDDSGKATGGNLFGWGIGHEIGHVTDIGKMTYSETSNNVLA
                     LLAQTFDDKTHSRIEGSTMDKIYEHVTSNSLGIPSNVFERLGMLWQLHLAYDDDFTGS
                     MLKNNSDADLSNDTFYAKISRKYRALSSSDPINSLPKDQMLVAMASSVVEKDLRDYFK
                     AWGVEITPELNSIMDSKNYEKESRKIQYVNDEARRKILNENIASMAKDTKVSASFSDG
                     IQSGSLVKSNKISIDLDVDKDKDKILGYEIIRSDGNYLDGENGTQVKYRTVGFVDAKG
                     NSKTKFTDNISPLNNRAFTYKVVAYDYHLNPTEEFEVGTVKLSDEGKINKSAWSFITN
                     TVSDGDVRTENDSHGPLQNPEIDNIKDNDANTTYKGKIISKAEWNKDPQKDPDINVEE
                     NPYIIVDMKETLPIVGLKYTKPETEARKFSLKGLFNFRKNTSTTYNPLTNYKIQVSND
                     KKNWEDVSQGTFEYGQDLVGGGKDQDNEARVTFNKDGKLWTYQARYVKLISNNKSNIE
                     VAELDIIGPPGDNIEIGTMNNADETRTNGIGKLAEDYVYQSDDSSTSEDETGKIPAGS
                     IVITGEYSGNPAFNLPLLIDKNNKTISGEALLFAEVPEKGELGEISKGTWVYYMPKEN
                     FDSLSDKVKAELYRYNDLQGDTPVGQRFVSDTMYVPVGAKNYDELKTISLTDSNSKAR
                     KATRNSIDISNKKVITVSNKVKGNIVRDK"
     regulatory      complement(27342..27427)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF01051"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="cyclic di-GMP riboswitch class I; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /bound_moiety="cyclic di-GMP"
                     /db_xref="RFAM:RF01051"
     gene            complement(27599..29002)
                     /locus_tag="ACGI5H_000432"
     CDS             complement(27599..29002)
                     /locus_tag="ACGI5H_000432"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861691.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall-binding protein Cwp9"
                     /protein_id="HFG9696164.1"
                     /translation="MKNSKKILAIGLTLFLVMVNTPMVNALTSVEQIKGNDRYETAAK
                     IADKQNYNTAILINSDNSLADGLSASGLAGALNAPILMTKQNQIPNTTMERLNKAKTV
                     YIIGSESTISKNVENQLLSKKKVVQRIFGENRFDTSIKIAEKIKEIKPIDKVIIANGF
                     TGEADAISASPVAARDGVPIILTDGNSVGFDTTGLKSYALGSSEIISDELVKSTNSIR
                     LGGTDRFETNKIVIQEFYKNSKEFYLSKGLQLTDALAASTIAKNAPVVLVENGSNKSI
                     LSGADKLTVLGGINQNVIKQCINQASPNQQGLYYNPNDRAFKERIKGKVYALTKQYRK
                     ENGVRALSVASRLEGLANDWSNLMANKKTLSHTINGKNSYSTFLKYLDWSEIKPGYIA
                     VQGENIIKYKIPDKPVYTNRDADDIGNFIFNEWKTNPEEGTNMLHKGYEIMGFGIAIT
                     GDKNLYATHEFYGRYKE"
     gene            complement(29464..31359)
                     /locus_tag="ACGI5H_000433"
     CDS             complement(29464..31359)
                     /locus_tag="ACGI5H_000433"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861692.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall-binding protein Cwp8"
                     /protein_id="HFG9696165.1"
                     /translation="MLSNKKRSMAIVMAGATVMSAAAPIFADNTVTENVDKNYTVSAK
                     DSAKLIEEVRKALEVKFEDTKAGANVNDRVYDIKVDNVNLTNATQLQNKINSLTEGQS
                     LKVTIQDKGHQVLGGKVVDYKIENYKTAQEIVDAVNAYNATLAEDSDNKLTATIKSTN
                     TVEVKRAKDSANVITLNVGDQHLDFSKVITSEEGTFEGYEKSYSDIDSKELHTITVKN
                     ADLQDISAEELFDGIRLTTLGREIVNKVKNGYALTFENEAILTQEQEDSDDKDKPEKS
                     SFDIVLSKANEKPETISVSSKNHKLVRDLHKVLTDVKGGKELKVEVLSGDSRFTTAVE
                     VSKERFKDGEAEAIILVGEDAIVDGLASAPLASQKNAPILLSKKDSLPSEIEAEILRV
                     LGSNLSSKKIYIVGGESKVSKETEEKLSKLGVSKVERVSGEDRFETSLEIAKQLKDTF
                     KTAFVVGGNGEADAMSISARAAQFGAPIIVTGNELDANAEKLLKGKELEIVGGENSVS
                     KEVEDKLVDIDLNNKVERLAGENRKDTNAKVINKYYAGATKAYVAKDGYVGGNGQLVD
                     ALTAAPLAASSKAPIVLTTEELSKSQEEVVELRLKNATKLVQIGEGIAKNAIEKIAEK
                     INLFTKN"
     gene            complement(31985..32128)
                     /gene="scfA"
                     /locus_tag="ACGI5H_000434"
     CDS             complement(31985..32128)
                     /gene="scfA"
                     /locus_tag="ACGI5H_000434"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891067.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="six-cysteine ranthipeptide SCIFF"
                     /protein_id="HFG9696166.1"
                     /translation="MENKHVKTLSQATLKQSAAKGGCGECQTSCQSACKTSCTVANQE
                     CER"
     gene            complement(32194..32556)
                     /locus_tag="ACGI5H_000435"
     CDS             complement(32194..32556)
                     /locus_tag="ACGI5H_000435"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454083.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR04086 family membrane protein"
                     /protein_id="HFG9696167.1"
                     /translation="MGKSNYIFKGLGYAYIITLAVLLVYNLFLTFTDIGGDNITMVSS
                     FITTISAAIGGFYTSKHMKEKGLMYGLLVGLLYIVCIFLTVFLAQEKFVFEVGMIYKL
                     LLISAAGGIGGVLGVNFK"
     gene            complement(32614..32907)
                     /gene="yajC"
                     /locus_tag="ACGI5H_000436"
     CDS             complement(32614..32907)
                     /gene="yajC"
                     /locus_tag="ACGI5H_000436"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426573.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_function: GO:0015450 - protein-transporting ATPase
                     activity [Evidence IEA];
                     GO_process: GO:0009306 - protein secretion [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit YajC"
                     /protein_id="HFG9696168.1"
                     /translation="MPQQQIIMSIGLWVVVIAIFYFLMIRPQKKKDKQLKEMRSSLSV
                     GDKVITIGGIVANVAKVEDDVVILELGPNRTKVPFEKWAIGTVKSKKEEIEED"
     gene            complement(33041..34162)
                     /gene="tgt"
                     /locus_tag="ACGI5H_000437"
     CDS             complement(33041..34162)
                     /gene="tgt"
                     /locus_tag="ACGI5H_000437"
                     /EC_number="2.4.2.29"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009906124.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0008479 - tRNA-guanosine(34) queuine
                     transglycosylase activity [Evidence IEA];
                     GO_process: GO:0006400 - tRNA modification [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA guanosine(34) transglycosylase Tgt"
                     /protein_id="HFG9696169.1"
                     /translation="MYAVRYELIKTCKQSGARLGRLHTPHGIIETPIFMPVGTQATVK
                     SMTPEELKEIGSQIILSNTYHLYMRPGHELIKRAGGLHKFMNWDKPILTDSGGFQVFS
                     LGPLRKIKEEGVEFRSHLDGSKHFLTPEKAMEIQNALGSDIMMAFDECAPYPSDREYV
                     KNSLERTTRWLKRCKDAHNNTDKQALFGIIQGGMYKDLREQSAKEITNIDLPGYAIGG
                     LSVGEPKPLMYDVLEHTTPLMPKDKPRYLMGVGSPDDLVEGVIRGVDMFDCVLPTRIA
                     RNGTAMTSQGKVVVRNATYAEDFTPLDPECDCYACKNYSRAYIRHLIKANEILGARLI
                     TTHNLHFLLNLMKQIRQAIMEDRLLDFRNEFFAKYGYEI"
     gene            complement(34241..34726)
                     /locus_tag="ACGI5H_000438"
     CDS             complement(34241..34726)
                     /locus_tag="ACGI5H_000438"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422818.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate-starvation-inducible PsiE family
                     protein"
                     /protein_id="HFG9696170.1"
                     /translation="MHSLQKQKKNNPILKIAFIFERVLAVVVLIAVFLGTIDVLRLMW
                     GAYIVDFQNPVQYSQLNDFLAQILLLVIGVELVVMLSLHIPGAFIEALLYAIARKMLL
                     LPKNEGMIDVLIGVIAIAGLFAIKKFLVTKDKSALNIMSIHDEEAIKEQQNKEDEDKS
                     I"
     gene            complement(34738..35763)
                     /gene="queA"
                     /locus_tag="ACGI5H_000439"
     CDS             complement(34738..35763)
                     /gene="queA"
                     /locus_tag="ACGI5H_000439"
                     /EC_number="2.4.99.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861694.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016740 - transferase activity [Evidence
                     IEA];
                     GO_function: GO:0016853 - isomerase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA preQ1(34) S-adenosylmethionine
                     ribosyltransferase-isomerase QueA"
                     /protein_id="HFG9696171.1"
                     /translation="MKTSDFKFDLPQELIAQVPIEDRASSRLMVLDKETGNIEHKVFR
                     DIIEYLNPGDCLVLNNTRVIPARLIGEKLETGGKIEFLLLKRTEEDTWQALVKPGKRA
                     KVGTKFSFGNGKLIGEVVDLSDEGSRIIKFHYDGIFEEILDELGNMPLPPYITARLDE
                     KERYQTVYSKHNGSAAAPTAGLHFTEELLNKIKEKGVDIAFVTLHVGLGTFRPVKVED
                     VLNHKMHSEYYMVSQEAADKINRAKENGKNVICVGTTSCRTIESACNEDGKMKETSGW
                     TEIFIYPGYKFKVLDKLITNFHLPESTLIMLVSAICGKDNVLNAYNEAVKERYRFFSF
                     GDAMIIK"
     gene            complement(36081..37100)
                     /gene="ruvB"
                     /locus_tag="ACGI5H_000440"
     CDS             complement(36081..37100)
                     /gene="ruvB"
                     /locus_tag="ACGI5H_000440"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422816.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0009378 - four-way junction helicase
                     activity [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction branch migration DNA helicase
                     RuvB"
                     /protein_id="HFG9696172.1"
                     /translation="MQGFEDENRIITSTMKMEDIDIENSLRPKTLEDYLGQEKSKEQL
                     SIFIEAAKSRNEQLDHVLLYGPPGLGKTTLASIIANEMGVNLRITSGPAIERAGDLAA
                     ILTNLNENDVLFIDEIHRINRSVEEVLYPAMEDFCLDIIIGKGPSARSIRLDLPKFTL
                     IGATTRAGMLTNPLRDRFGVICKLDYYTVDELSKIVLRSSSILDAEIQSNGALELAKR
                     SRGTPRIANRLLKRVRDFAQVRADGKITDKVAKDALELLGVDSLGLDFVDEKLLMTII
                     EKFRGGPVGLDTLAASIGEDRNTIEDVYEPYLLQLGFINRGPRGRVAMPLAYEHLKIP
                     YPNEK"
     gene            complement(37207..37809)
                     /gene="ruvA"
                     /locus_tag="ACGI5H_000441"
     CDS             complement(37207..37809)
                     /gene="ruvA"
                     /locus_tag="ACGI5H_000441"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891076.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009379 - Holliday junction helicase
                     complex [Evidence IEA];
                     GO_function: GO:0003678 - DNA helicase activity [Evidence
                     IEA];
                     GO_function: GO:0009378 - four-way junction helicase
                     activity [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction branch migration protein RuvA"
                     /protein_id="HFG9696173.1"
                     /translation="MYSYIKGTVEEIYIDSIVVENNGIGYKINVSSNTIMNLQVGEAT
                     KIYTKLIVREDDMSLCGFVSREELKMFELLTSVSKIGPKVALSILSFASPAQLGAYIL
                     SEDIGKLSKAPGVGKKTAERIVLELKDKVDKNNIEFEPTLLSQKPTLISQDESVDALV
                     ALGYTLSESKEAVQKCKKDGMNTEAIIKKALTYIMSKSLK"
     gene            complement(37802..38311)
                     /gene="ruvC"
                     /locus_tag="ACGI5H_000442"
     CDS             complement(37802..38311)
                     /gene="ruvC"
                     /locus_tag="ACGI5H_000442"
                     /EC_number="3.1.21.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422814.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008821 - crossover junction DNA
                     endonuclease activity [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="crossover junction endodeoxyribonuclease RuvC"
                     /protein_id="HFG9696174.1"
                     /translation="MIILGIDPGIAIVGYGIIEYKNSKFKAIDYGAVTTPAHMNISRR
                     LELVYKGIDTIVKNYNIDEVGMEELFFNKNVKTAITVAQARGVTMLACAHNGKPVYEY
                     TPLQVKQGVVGYGRADKAQVQQMVTSFLSLKKVPKPDDVADALAVAICHAHSNKLEKT
                     LKNIGGKYV"
     gene            complement(38623..39252)
                     /locus_tag="ACGI5H_000443"
     CDS             complement(38623..39252)
                     /locus_tag="ACGI5H_000443"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897973.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9696175.1"
                     /translation="MFEKKKKELFPWKISALILVGVFVLSSGVYIGTRLKHNGVQTGE
                     VVSTSANMNEKSKEAFGLNKNCEVWLQSEGENETNYKRTLTMAGIVPESLLDKTKSEI
                     VSYFKKEYPTKKIKSMDKNEIILVESKYSDNKDVQAMDVTIKGKYTIENDNGNIALYK
                     YDDSGSKTLVEKTKIRVDSLPKTVQDEIKKGVVMDTEEEAYSRLEDFAS"
     gene            39455..39778
                     /locus_tag="ACGI5H_000444"
     CDS             39455..39778
                     /locus_tag="ACGI5H_000444"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422812.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1540 domain-containing protein"
                     /protein_id="HFG9696176.1"
                     /translation="MERINCNVINCSHNNSHICYADKIFINGEKAHNDRHTCCSSFLD
                     ESIYSNLSSNVNNKNCEELVCTVKNCKYNKDGSLCTLDNILVAPETDRVNLYIETCCS
                     SFECK"
     gene            40046..40900
                     /locus_tag="ACGI5H_000445"
     CDS             40046..40900
                     /locus_tag="ACGI5H_000445"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454079.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative ABC transporter permease"
                     /protein_id="HFG9696177.1"
                     /translation="MSTFYIQFLYFVIYSFIGWCCETTYCSVLQKQFVNRGFLNGPFC
                     PIYGFGALAIVATLTPFVHNIPLLFLFSIIITSIMEYCTSFILEKIFNMTWWDYSKHK
                     FNIHGRVCLENSLMFGVLSLIVMLIVHPIVVDFINSISKNVLFIFAISIEIYFVLDLV
                     ITVHTILQLNGKLKQINLIIKELKDKKEYYKLITQETIENKLESLVENRLDTLEDRFE
                     ILKEKENYRYAKNRIDELKNKLNTLLSNHKLLHRRIIKAFPNISSNKHTDILNKIKEN
                     IKSIKKDK"
     gene            complement(41086..42522)
                     /locus_tag="ACGI5H_000446"
     CDS             complement(41086..42522)
                     /locus_tag="ACGI5H_000446"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426589.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="four-carbon acid sugar kinase family protein"
                     /protein_id="HFG9696178.1"
                     /translation="MREVKPISIDILNTFKQVDEDRLNKLLADELKHLDRKIVVLDDD
                     PTGVQTVHDISVYTDWDKDSMEQGFNEKNSMFFILTNSRGFTVAQTTKAHKEISKNIV
                     DVSKKVNKDFIIISRSDSTMRGHYPLETNLLKSEVERLSGKLFQGEIIMPFFKEGGRF
                     TIDNVHYVKEGEILVPAGMTEFAKDKSFGYKSSDIGEWCEEKTNGKYKSSDMIYISSK
                     ELRELNIEAITEKLKKAEGFNKIIVNATDYVDVKVFTIAFIRAVNGGKEFMFRSAAAI
                     TKVLGGVSDKELLTKDELVSKGNTNGGIILVGSHVNKTTQQLEELKNCKYPIEFIEFN
                     QHLVLQENGLKNEVKRVIKVVEEKISSGKTVAVYTRRERFDLDTNDKDKQLMISVEIS
                     DAVTSIIGMLNVRPNFIIAKGGITSSDVGTKALRVKKATVMGQIKPGIPVWMTGKESK
                     FPNMPYIIFPGNVGEISTLRESVEILMG"
     gene            complement(42593..43975)
                     /locus_tag="ACGI5H_000447"
     CDS             complement(42593..43975)
                     /locus_tag="ACGI5H_000447"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422807.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0015128 - gluconate transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0035429 - gluconate transmembrane transport
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="gluconate:H+ symporter"
                     /protein_id="HFG9696179.1"
                     /translation="MITGYGLLIAFVISIGILLVSIIKFKVNPFLALLITSIITGFMV
                     RMPINEISTTISTGFGNTLGSIGIVIGLGIIFGNILSESRATESIAKGLLAKTGEKNS
                     ALAVTTAGFLISIPVFMDAAFVIMMPIIKYVSRVTKKSLMVFVCALGVGTIVGHALVI
                     PTPGPLAVAANVNANVGSFILYSIIVAFPAALIGGWIYGKRFEKYPAYAIDENDREKN
                     LEQGKDSIKIEDDDSSKVPGFGISMFSLLFPILLILISNVFSMFLEKGSTMSGVLAFI
                     GDKNIAILLGILVAIGFLKKYINKPMGDVVIEAADSAGLILLITGSGGAFGSVINASG
                     IGNFLVDTMSGLSISVVVLGFLLSALLRISQGSATVALVTTSSILGPTILATGMSPVL
                     VGLAICAGGVGFSLPNDSGFWVLSRFSGLSVKDTLNSWTIGGTIAGVVAFIMVLLLSV
                     INGIIPLPGL"
     gene            complement(44111..45019)
                     /gene="garR"
                     /locus_tag="ACGI5H_000448"
                     /pseudo
     CDS             complement(44111..45019)
                     /gene="garR"
                     /locus_tag="ACGI5H_000448"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426591.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0008679 - 2-hydroxy-3-oxopropionate
                     reductase activity [Evidence IEA];
                     GO_process: GO:0046487 - glyoxylate metabolic process
                     [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="2-hydroxy-3-oxopropionate reductase"
     gene            45412..46083
                     /locus_tag="ACGI5H_000449"
     CDS             45412..46083
                     /locus_tag="ACGI5H_000449"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422805.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HFG9696180.1"
                     /translation="MATFKRLQEQAYDYLKELILSGEMIENEIYSETKLASEIGISRT
                     PIRDALQRLSQDGFIDIIPSKGFRIHQITANEIVEIFQIRSAIEGFCTFLITSQYKEA
                     RAVETISKLKHLLDKQKDILLGDKNLNSFAEYDTLFHTTIVSYAQNTEFDKMFNNYMY
                     RIKKLALDSLSHEGRLETTLKEHTDIFNNIANGCIEDIYRTTLIHMETPKYINLEDFC
                     NNKLF"
     gene            46186..46734
                     /locus_tag="ACGI5H_000450"
     CDS             46186..46734
                     /locus_tag="ACGI5H_000450"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454071.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9696181.1"
                     /translation="MIFLNEDVVTNETIDKDYAIEEVRMACKHFGDLYFYFSKVLFEE
                     FGEDKTSEILRKVLFERSEERAIAMRERAHENGDELIADNIISTTDVPFLGWVPEFEE
                     LHCPYGASWLLRFEENPWFKKFASLYCDVTDTTVAEVFTGDTSHKITKNILWGDKSCE
                     RIYFHDDKVSEGKYTYGNKNCK"
     gene            46996..47304
                     /locus_tag="ACGI5H_000451"
     CDS             46996..47304
                     /locus_tag="ACGI5H_000451"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422803.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9696182.1"
                     /translation="MFNKIYEKKEFIVFQVKKGYVVYNTRKSFEEGHTHLKHFEAAKT
                     AIDLAINKKIPRSKDGYYLTSLIRISDDGYYIDKLSELLYVREQKGKKEKYCNSGYQM
                     "
     gene            complement(47466..49256)
                     /locus_tag="ACGI5H_000452"
     CDS             complement(47466..49256)
                     /locus_tag="ACGI5H_000452"
                     /EC_number="7.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426617.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HFG9696183.1"
                     /translation="MKKSKGFKKTIGRLLPFVKKYKFSFIIAIICIISAATMNALAPK
                     TEGLIITQLTKDVISIAKGVPGASVNFDYVTKILVILACIYFANAIFTYTSSFLLTNA
                     IQNTMRDLRNEVENKIRRLPISYFDSNSFGDVLSRISNDVDTISNALQQSFMQIVNSI
                     LVIILALSMMFTINIYMALIALFIIPISYFVSKFVVKKSQSRFSLQQNALGKLNGKVQ
                     EMYTGFNEIKLYGKEEDSIKEFKKVNQELCENGFKAQFISSMMNPMVSLVTYFGIAAV
                     AVVGSIYAVSGGITVGNLQAFVRYIWQINQPLSQMTQLSTVIQSSFAAIERVFEILDE
                     EEEIPDVENPVKIENVKGNVTFEHVNFGYGENSTLIEDLNAEVKSGQMVAIVGPTGAG
                     KTTLINLLMRFYDVKKGAIKIDGVDIRDMKRKDLRSMFGMVLQDTWLFNGTIFENIEY
                     GRFGATKEEIIQAAKVANVHHFITTLPDGYNMFLNEEASNISLGEKQLLTIARAFISD
                     PSILILDEATSSVDTRLELMLQKAMRNLMNGRTSFVIAHRLSTIRNADLILVMNNGSI
                     IEQGNHDELMEKGGFYEKLYNSQFADKESE"
     gene            complement(49256..50983)
                     /locus_tag="ACGI5H_000453"
     CDS             complement(49256..50983)
                     /locus_tag="ACGI5H_000453"
                     /EC_number="7.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891091.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HFG9696184.1"
                     /translation="MKLILSYLKNYKLLIVLNILAIFSFALVELGIPTIIAKIIDNGI
                     ANQNIAYIKQMGIVIVIISIIGVVGSILLGYCSAKVSTSVTRDIRNDIFEKSQEFSHT
                     EYNKFGISSMITRTTNDAFQIQQFVNILLRTALLTPVMFIISIIMTIRTSVELSIVLA
                     ISVPFIIIGVAIIAKVSQAISSKQQKGLDKLNLISRENLTGIRVIRAFGNDDYETERF
                     EKTNTYYANVSKKLFKLMSITQPAFFLLLNIAVLAVFWISSEKINIGELQVGQLVAFL
                     EYLFHAMFSIMLFSMVFIMYPRAEVSANRIKELLNEEPLIKNPENGIKDTENKGIIEF
                     DNVTFTYPDGEASVLKDISFTAKTGETVAFIGSTGSGKSTLINLIPRFYDVTEGSIKI
                     NGVDIREYDLKALRKKIGFIPQKSLLFTGSIANNIRFGKHKAGESELEYSAKVAQAYE
                     FISKKPRKFDELISEGGANVSGGQKQRLSIARAIIRRPEIYIFDDSFSALDFKTDAIL
                     RAKLKKETKDAIVLIVAQRISSIIDADKIIVLNEGQVVGMGTHKELLKNCEIYYEIAT
                     SQLKKEELE"
     gene            complement(51228..51494)
                     /locus_tag="ACGI5H_000454"
     CDS             complement(51228..51494)
                     /locus_tag="ACGI5H_000454"
                     /inference="COORDINATES: protein motif:HMM:NF013989.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrofolate reductase family protein"
                     /protein_id="HFG9696185.1"
                     /translation="MNLEPKKLIEQIGKEKDKKDIWIVGGGDIVKLFMKDNLIDDYYI
                     YILTIILGRGISLFKSGIDKTNLNFKKASNIGELVKLEYSKKQK"
     gene            51792..52904
                     /locus_tag="ACGI5H_000455"
     CDS             51792..52904
                     /locus_tag="ACGI5H_000455"
                     /EC_number="5.1.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422798.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alanine racemase"
                     /protein_id="HFG9696186.1"
                     /translation="MKISEVATPNFLLDLDQLEKNIDKIQQICTNNNKQLWPMLKTHK
                     STYIARLQKNAGASGFLVGTLDEGEALIKAGFEDIMLAYPYMGEVNINRIVTMASKIN
                     LICATDNIECAKAYSEAFSKSKIECKLLIIVDCGLHRFGVEPEKVVELATEISKLENI
                     KIVGISSHPGQVYGCSSPEGVPDVCVQEDSSMEKAYKALTDNGFNIEIVASGSTPTVE
                     SEAASKTITAVRPGNYVYYDAIQIGLGCATEDMCALTVVCTVISKNSSGYYLIDCGSK
                     CLGLDKGAHGNSSIVGYGRVCGHPELTIDSLSEEVGKIKVNGETDIKIGDRIRIIPNH
                     SCSTANLTSNLLGFRGDTIEKVIEVDIRENSKQIIL"
     gene            complement(53268..53777)
                     /locus_tag="ACGI5H_000456"
     CDS             complement(53268..53777)
                     /locus_tag="ACGI5H_000456"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426630.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YjiG family protein"
                     /protein_id="HFG9696187.1"
                     /translation="MSQQNTGNVIVNSKPKKTAVEIFMGGAKKGFYIGVEQILPAMIM
                     GYVIVQFLQLTGLVDILGNIFGPVMGIFGLPGESVVVLIAAFFAKAAGAATAANLFAQ
                     GLITAPQATILIMPCMLMGTLVGHYARIVLVANASTKYRMLLLAVPIFDAIVGMLIVR
                     VLLTVMGLM"
     gene            complement(53779..54426)
                     /locus_tag="ACGI5H_000457"
     CDS             complement(53779..54426)
                     /locus_tag="ACGI5H_000457"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003431751.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside recognition domain-containing
                     protein"
                     /protein_id="HFG9696188.1"
                     /translation="MDVTAGDNKVTWKGYLSLFVLIVLFSGVFKDSQGFLKALDFANL
                     TGSFGTIADGVDFMGKGGTGAKDGFLFALTLIPTVCFAVGLIDVVESMGGMKAASKIF
                     NPLLRPLLGIPGIAGIAFVSSFTSSDVASIMTKELFESGEITDDERTIFVAYQYAGSA
                     VILNTINTQAPLLPIALLALGPIILIEIFCKILGANLVRLIIGVRNKKNKAKEAV"
     gene            complement(54440..55612)
                     /locus_tag="ACGI5H_000458"
     CDS             complement(54440..55612)
                     /locus_tag="ACGI5H_000458"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436151.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M20 family metallopeptidase"
                     /protein_id="HFG9696189.1"
                     /translation="MNTYLNEISKFVDENREEIVSLWKEIVNMESYTHCKESVNKLAK
                     RLKFEFEKEGLDCELVDVGDNGSTLIGTLGSNIDKKPIIFSGHMDTVFETGTFGENPF
                     KIIEGKAYGPGVLDMKGGIIISLYAIKALNKIGYKERPIKIVFSGDEEIGHKDSTGAD
                     VILREAKGGLCAFNMETGLVDNSLCVGRKGRIGCNIHVKGVETHAGNDFEGGRNAIEE
                     MANKILRIQKLTNLDVGTTVSVSVIKGGRVENSIPEDCSIKVDLRFEKVEEMENVKEQ
                     VREICKETYIEGTSTEVNFISEMMPFETTEDVMRFHTFVNEVSKENGFGELNAKRLGG
                     SSDASYLTIANVPTICSFGVRGEWNHTSREYAVVDSMFERVKLISTVILNLDKFEV"
     gene            55880..57256
                     /locus_tag="ACGI5H_000459"
     CDS             55880..57256
                     /locus_tag="ACGI5H_000459"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436150.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9696190.1"
                     /translation="MKYKIGFLTTSYFMSDKFKQALKELNDTCEITFIELKGENPFNN
                     LPNIYYEQVDNFDGFVCSGIVPYSELIINIKDIKVPLNFLKLDEKDFYKYLFKLLNSQ
                     KDIDFTKSFMDFLREDNNYYDIYSLIDSNKCPYTIKDFNIPQPVYDFKKLNDKLLEIH
                     LDLLRDNKINLSFTRNYIISCELNKLGYDSIYMVPSTESILNTFKSLVNEITLQNLDK
                     NKSATCIVTVNSSEYINEDLIFKNDEIQNQIYNTILNSLSRHGFYGVQVKKNDMKIEI
                     HTTKEMLNNMTNNYTDFFISEDLKEIKYSLNIGWGIGNTNIHAEQNARQANGKSASLN
                     GNCTFIVNDTNDTIGPLYSNKNSNNIEDSSIANKVASFIPLSNTNVSKIMCMINDRNS
                     NNVSAEILADYMNITLRSANRILSILYKAGIATIVNTKLDNQRGRPKKIYKVDFLSFL
                     NKMQKLNS"
     gene            complement(58192..58722)
                     /gene="bilS"
                     /locus_tag="ACGI5H_000460"
     CDS             complement(58192..58722)
                     /gene="bilS"
                     /locus_tag="ACGI5H_000460"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436147.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0010181 - FMN binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="flavodoxin family protein BilS"
                     /protein_id="HFG9696191.1"
                     /translation="MKSLVLYSSLTGNTKKIAYTIYDEIQEEKDIKDVNELVDYGIDY
                     ENYDIVFLGYWVDKGICDKNSKQVLENIHNKKIALFGTMGASKKGSYGASIIEKIESI
                     IPKDNEILGSFICQGKIAEGLKAKYKEMLKLSPDNEHIRQQLNNHEESQSHPDEQEIY
                     EASMFAKNMMIKASIV"
     gene            complement(58810..59904)
                     /gene="bilR"
                     /locus_tag="ACGI5H_000461"
     CDS             complement(58810..59904)
                     /gene="bilR"
                     /locus_tag="ACGI5H_000461"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728945.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bilirubin reductase"
                     /protein_id="HFG9696192.1"
                     /translation="MYCNLLKPIKIGNLELKNRVSFAPTSMGLKLEEKIKKFSDIAKS
                     GVALITLGDVSIRPSFHKVAISLSDEDGVMKYKKIVDEIHNSGAKVSAQLFCSDYDVN
                     LIKDTMNMGITSHDEIKKIMNDGVKDYITNMPKEEIKNIINLFKVTALNAKKAGFDMI
                     QIHGDRLVGSFSSSIFNNRNDEYGRTCDNRSRFASEIISSIRDEVKDIPIDYKFAIRQ
                     ENPHYGNAGVLLSEVEYFVKKFESLGVNSFHVTLANHSKLEDTIPTNNHPYFKEEGCF
                     LYLADEVKKHTNLPVCGVGKLSSPDFIESIISNNRVDMVSMSRQLLADSNWLQKVKDG
                     RVDEIKKCCYCNKKCADALQTRSQFGCILD"
     gene            complement(59906..60352)
                     /gene="bilQ"
                     /locus_tag="ACGI5H_000462"
     CDS             complement(59906..60352)
                     /gene="bilQ"
                     /locus_tag="ACGI5H_000462"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436142.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="bilirubin utilization transcriptional regulator
                     BilQ"
                     /protein_id="HFG9696193.1"
                     /translation="MDFKNLQYESLSYIICNLQKNFKLYCEKCLKPYKLTNGLYFYLI
                     YINKNRNCSLNDVSTEFEVDKAHTTRTISRLEQDGYIEKIQNPNDSRAFQLRVTDKGE
                     EVLGDIKNIFSKWDNHIKKEFSDTEYKELVKNLHVVKDIKTAVEEE"
     gene            60658..61848
                     /locus_tag="ACGI5H_000463"
     CDS             60658..61848
                     /locus_tag="ACGI5H_000463"
                     /EC_number="2.6.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422792.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003824 - catalytic activity [Evidence
                     IEA];
                     GO_function: GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA];
                     GO_process: GO:0009058 - biosynthetic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal phosphate-dependent aminotransferase"
                     /protein_id="HFG9696194.1"
                     /translation="MISNKMQTLVANSSVIRAMFEEGKKLSDIYGEENVFDFSIGNPS
                     VEPPETIKAVINDILNEESPNLVHGYMNNSGYEDVRDAIAEHINKKDGLNLTRENLIM
                     TCGAAGGLNIILKTLLNPGDEVIAFAPYFGEYKNYTENYDGKLIEVPTNIETFEPDLD
                     ALKNAITPKTRALIINTPNNPTGVIYSEELLKNLGELLDSKQKEFNTSIYLISDEPYR
                     EIIYDGAKVPCVLKYYRNSFIGYSYSKSLSLPGERIGYIVANGQMDDFDDVMSSLNVA
                     NRILGFVNAPSLFQRVIARSLDAEVDVNIYKKNFDLLYNSLIDMGYSCVKPNGTFYLF
                     PKAPIEDDKKFCNDAKQFNLLLVPGSSFGCPGHFRVSYCVSYDKVKSSLPAFEKLAKL
                     YNLK"
     gene            62018..62980
                     /locus_tag="ACGI5H_000464"
     CDS             62018..62980
                     /locus_tag="ACGI5H_000464"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728946.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DMT family transporter"
                     /protein_id="HFG9696195.1"
                     /translation="MKKGYVYIILTTLFFSSMEISLKTVTNDFNPLQITLSRFFVGGL
                     VLLPFAVKRLRALSLSITKSDLKYFAFLGFMCVVVSMSLYQLAVLNTKASVVAVLFSC
                     NPVFVMLLAYLILKEKIYRHNVISLILEVLGIIVIINPLHTKLTLSGIFLTLSSAIIF
                     SMYTVFGKRKTLKFGGIVVTCFSFIFGSLEMLILVLLTKINFIADILNKNKLHVFANI
                     PIFSGYTLHNMPIMIYVFVFVTGVGYALYFMAMEATSTSLTSLVFFFKPVISPILALL
                     ILKEIIPINMVIGILLIVIGSIISIIPTIITQMHNKHVEALYKE"
     gene            complement(63102..63764)
                     /gene="zmp1"
                     /locus_tag="ACGI5H_000465"
     CDS             complement(63102..63764)
                     /gene="zmp1"
                     /locus_tag="ACGI5H_000465"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861706.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc metalloprotease Zmp1"
                     /protein_id="HFG9696196.1"
                     /translation="MRPSKKLLIAIISIFLISSVPVSAHADSTTIQQNKDTLSQIVVF
                     PTGNYDKNEANAMVNRLANIDGKYLNALKQNNLKIKLLSGKLTDEKEYAYLKGVVPKG
                     WEGTGKTWDDVPGLGGSTVALRIGFSNKGKGHDAINLELHETAHAIDHIVLNDISKSA
                     QFKQIFAKEGRSLGNVNYLGVYPEEFFAESFAYYYLNQDTNSKLKSACPQTYSFLQNL
                     AK"
     regulatory      complement(63864..63949)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF01051"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="cyclic di-GMP riboswitch class I; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /bound_moiety="cyclic di-GMP"
                     /db_xref="RFAM:RF01051"
     gene            complement(64135..67053)
                     /locus_tag="ACGI5H_000466"
     CDS             complement(64135..67053)
                     /locus_tag="ACGI5H_000466"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_021362860.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SrtB-anchored collagen-binding adhesin"
                     /protein_id="HFG9696197.1"
                     /translation="MKKGNRKALLISLIMILSMVVSTIYPTVSYASELGENSQIQSGS
                     TNSSTGEEKESDNKKPEQTPEKDKATDNKKPEQTPEEEKPTDNKKPEQTPEEDKSTDN
                     KKPEQTPEGEKPIDNKKPEQIPEEDKSTDNKKSEQALEDEKPLDNKNTEKTPEEDNLL
                     ENENLLKVLEEELNEENEDYGFVVKINNNTIETESMKKISFNLTYTPTSKGIQAGDSI
                     TFKVPDVFNKVNLDYTSECFDKTESNGEYTLTFRELPNGQSVMQGKIGLEAYVKKVDE
                     DTNAKIHIETTGKIESGSGDIDVEIKPGDKTDVPDAKGTLKKLVEGKKSTTVFMPVKN
                     KDINYSIQVNEKQEELKDIILYDELPEGLTLINGSVSVVTSDGKEVSDFNIEQSKNSI
                     SVNLGNIDKSYTVKYKARISDKNAKHGNKYKNVARIESDGKKIQEDDATVSIFDRGDD
                     YLLTKGHSGATNITQVGQVINYQISINDDKSPISNVVITDNIPEGMRLTTSGEAGHDF
                     RVVEIPMNGSWTPWSKEKIANNISYKVEEKRNESGQVDKVITGFTINLSKEEVESKFF
                     IAYTLKVISIEDSYINRAVLDANNSEIDKNDEINFKKNSGLISAKKEVDKKVLNSSDN
                     QIVKYKINMSTYGVYDAGQVNLLDEVNSALEISNIKYSDNLELKKEAGDGKNTIRLVN
                     KYEFKQIKEGEPVQSWVTFDADFTNVKVGETIRNVAQINGSSPPGVETTKQGYAFEAK
                     KVDALDKNVLSGAKFNLEDAFGNIVVKDLVSDEDGIIQSSIKKPGTYYLVEIMAPSGY
                     EKLKDKIKVEIGNKDIGRIVDIGNIENIRQENPPVNPPAPPNTDEPIVNPPVPPSTDK
                     PRKPSSSSDTEDTIVINPPIPPSEDIINPPIPEVLNPPVPPSEEMIETPVKQIIPIPE
                     VVKPSVSEEKNNKVKDDTLVNPPVPPKTGDSTTIIGEILLVIGAIVGLIVLRRNKNTN
                     "
     regulatory      complement(67171..67256)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF01786"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="cyclic di-GMP riboswitch class II; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /bound_moiety="cyclic di-GMP"
                     /db_xref="RFAM:RF01786"
     gene            complement(67383..68561)
                     /locus_tag="ACGI5H_000467"
     CDS             complement(67383..68561)
                     /locus_tag="ACGI5H_000467"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891122.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008324 - monoatomic cation transmembrane
                     transporter activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cation diffusion facilitator family transporter"
                     /protein_id="HFG9696198.1"
                     /translation="MFSKILVKTFIRDSENVQNTDVRNKYGYVAGVVGILSNLLLFVI
                     KVFIGMLTSSIAIMADAFNNLSDMASSAITMIGFKLASKPADKEHPFGHGRIEYLSAL
                     IVAFMVMLVGLQFVKSSIERIVNPIPVKFEVIPLILLIASIMIKIWLSRFNKFMGNKI
                     DSSALKAVSLDALGDVFTSSCVVISFIVARFTNFPIDGYVGIVVSLVILYAGFSLVKD
                     TINPLLGEAPDEEMVNSIIELLLSYKYIIGTHDLIIHNYGVGRCIASIHAEIPSNIDI
                     MEIHEIIDTAEREISEKLDIYLVIHMDPICLEDKEVMSAKKELEEILKKNSLVKSMHD
                     FRIVGKGSKKNLIFDIVVNPSEFSKNMSEDDLKEDITKLVKEINPEYNCVIVVDKDFI
                     "
     gene            68936..69121
                     /locus_tag="ACGI5H_000468"
     CDS             68936..69121
                     /locus_tag="ACGI5H_000468"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891124.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="proline--tRNA ligase"
                     /protein_id="HFG9696199.1"
                     /translation="MFFISDIYTKSPIKFDTPLQKEAYKILQKLDIDFECVDTDEAIT
                     MEDCVQINKKLNMKMVI"
     gene            complement(69186..71960)
                     /locus_tag="ACGI5H_000469"
     CDS             complement(69186..71960)
                     /locus_tag="ACGI5H_000469"
                     /EC_number="7.2.2.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891126.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0005388 - P-type calcium transporter
                     activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006816 - calcium ion transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="calcium-translocating P-type ATPase, PMCA-type"
                     /protein_id="HFG9696200.1"
                     /translation="MRYYNKPTKEVLKYLKTNPEIGLDDNEVEERKLRYGLNEFTIKE
                     GRTFWDELGESLTEPMILILIGAAVISSFVGELHDALGILGAIFIGISIGIITEGKSK
                     KAAHALSKLTENIEVKVLRNGKIIKISKNDLVPGDIVYIETGDMIPADGRLIQSINLK
                     LREDMLTGESDDVAKNADAVLDMEVVYSKTEIIEQDAIPAKQVNMVFGGTLVAYGRGI
                     MVVTHTGDKTEMGKIAQNLSNEDQQTPLQIKLGKLGAKIAGISGIIATLLCMFMIIQM
                     QRKGMLILDTSSILSFLQSLEPAKNAYMVCIALIVATVPEGLPTMINITLAITMQKMA
                     KINALVTKKEACETIGSVSVICSDKTGTLTQNKMMVEVAYVDGKYISGGEYQSNSYFE
                     QNCIVNSTADIEKEDNSFKYIGSATECALLLYHNDKNYNEMRKQTYLISQIPFSSEEK
                     KMSTLIRQEDSDILLSKGAPEVLLKKCSYVQQGKNIVPITPKVEKSILDEIKKLQIKS
                     MRTLGFAYKKMSNSKTEVAMTSEGELNLIGNSRSYMKEDNLVFSGFVGIVDPLREGVK
                     DSIDKAFNAGVDVKMLTGDNINTATAIGNELGLLNDGKKAVEATYIDVLTDKELREEI
                     KGISIVARSKPDTKMRIVSALQKSGEVVAVTGDGINDAPALSQADVGIAMGISGTEVS
                     KNAADIILTDDSFSTIVEGIKWGRGIYENFQRFIQFQLTVNIVAFIIAIISQLTGKDM
                     PFTTIQLLWVNIIMDGPPALALGLEPVRDYVLKRKPINRHSGIIARSMFVNIIINAIL
                     IITIVFTQSAFNILGATSEEQGTVIFSLFAFSALFNALNCREFGLNSTIPNFFKNKLA
                     LQIIVVTGIIQIIFTQVFQSFFNSVSLDFDMWIKIILFASTILLSNEFVKLILRTMKN
                     SRTMNFNSKN"
     gene            complement(72132..73388)
                     /gene="glyA"
                     /locus_tag="ACGI5H_000470"
     CDS             complement(72132..73388)
                     /gene="glyA"
                     /locus_tag="ACGI5H_000470"
                     /EC_number="2.1.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422786.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004372 - glycine hydroxymethyltransferase
                     activity [Evidence IEA];
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA];
                     GO_function: GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA];
                     GO_function: GO:0070905 - serine binding [Evidence IEA];
                     GO_process: GO:0019264 - glycine biosynthetic process from
                     serine [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="serine hydroxymethyltransferase"
                     /protein_id="HFG9696201.1"
                     /translation="MLKTTKISDPELYKIVADELVRQEHNIEMIASESTAPTEVLELS
                     GCVFTNKTEEGYPGARFQAGSEEADKLETLAIKRAKEVFGAEHVNVQPYSGSTANYCV
                     YSSILKPNDTVLSMRLDQGGHLTHGSAVNFLHDIYKYEFYGVDPNTGRIDYDALEAKA
                     KECRPKLIIAGASSYPRLIDYERISKVAKEVGAYFMVDMAHVAGLVAAKVIPSPVPYA
                     DFVSSSTTKTFCGPRSGIVLCKAEHAKKLDKGVFPGTLGSIHLNTVAAKAFSLLYLST
                     DKFKKIMEQVVVNAQTLASELISHGFSIVSGGTDNHIVMVDLRSKNLTGKQFEKALEY
                     VGITVNKNVIPDDPQSPFVTSGVRIGLTSISQRGLKEKEVIQIAGIMNKVAENIDNKE
                     VLDECKAEAQELISKFPLYPEGYFED"
     gene            complement(73460..74962)
                     /locus_tag="ACGI5H_000471"
     CDS             complement(73460..74962)
                     /locus_tag="ACGI5H_000471"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891132.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AbgT family transporter"
                     /protein_id="HFG9696202.1"
                     /translation="MRALNVVERAGNKLPDPVTIFLLLCIIVVILSAVISNLGVEEIH
                     PSTKEVVKVVNLLEKEQIQSYLGSIVTNFQSFAPLGLVLVTMLGAGVAEKSGFMEVLM
                     KKGISKVPQKLVTVAIVFAGMLSHTAADVGFIILPPLAALVFLGIGRHPLVGMFAAFA
                     GVAGGFAANVMLSTTDVLLAGFTIPAAQMMDPSYQGNPAMNLYFAFISAIVLTFAGAF
                     VTEKFIAPRFTKYNDSTNDKDIQELSELENKGIKYALLSLLVVVVVIVALCIGDNAFM
                     KDPETGSILSSNAPLMKGIVPIITIIFLTPGLVYGKVSKKIKSDKDLVSMMGSSMSDM
                     GGYIVLAFIASQFINLFNLSNLGTILSITGAKLLAESGIPSYGLIIGFILLSGFINLF
                     VGSASAKWAILAPIFVPMFMLLDFNPALTQIAYRIGDASTNPISPLFPYFPVILAFAR
                     RYDKDIGIGTVISNMIPYSVVFTLIEIIILLLFMGIGIPLGPGGGISYVL"
     gene            complement(75053..>76266)
                     /locus_tag="ACGI5H_000472"
     CDS             complement(75053..>76266)
                     /locus_tag="ACGI5H_000472"
                     /inference="COORDINATES: protein motif:HMM:TIGR01891.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="M20 family metallopeptidase"
                     /protein_id="HFG9696203.1"
                     /translation="KFWRGVSMHELILISEKYKEDILDFFTDIHMHPELSFKEFRTTK
                     AIKDLLVSLDIEILDLGMETGVVGLLKGKYDGPTVALRGDIDALPIYEEVDIKYKSRY
                     DGIMHACGHDIHTSCLVGCAYVLSHIRDSLHGNVKFIFQPAEEVNKGAKMLVERGVME
                     NPKVDAIFGLHNHPDIPCGKIGVKLGGLMAAVDTIKIEVNGFGGHGGIPNRTIDPIVA
                     SSAIIMGIQTIVSRNISPLESAVISIGTINGGTANNVISEKVDMTGTCRSFSNEVRKK
                     ISENLENIVCEIARGYQATAKLDYLFDLPAVINSKEMYAIACKSVCDLYSEDAIVDPI
                     PSTGGEDFSIFMEKAPGFFYWLGVGNKEQDCIYQWHNPKFKADKNSILVGTNVLCQSV
                     INYMDKLKNKI"
BASE COUNT        23763 a        13525 c         8664 g        30314 t
ORIGIN      
        1 agattatttt tctttattct agttttgtca atacttttat ttattttttt gttacattca
       61 attccaatcc ccatgttacc tccccaaagc ttattcaaat atatactaaa ctacatattt
      121 atctataaat ctatttgtat ataaacctgt ttaactacat aactttagaa caattacaac
      181 aaacacttca cttaaatata tatattctta gctaagaaat ttctttagaa atccaagctt
      241 atctagtata tcttgtattt tattgacttt ttgacttata gaatctatag ctttttcaat
      301 tgaatctact ttagcctcta aatcttcaac ctgattaact tttttatcta tagtaccatt
      361 attagttata tcactattag atgaattatc tataagtttt cctatatatc catcattaat
      421 caattttgta tcattagcag aagctaatat catcaacgta tctatatctg aatttctagt
      481 attttctata actctaccat ttttgtcacg aactgacaat atagtgattg tatcatggtt
      541 attaaatcca ccttctccaa tatttctaac tataacattt accaaagtag catagttatt
      601 cacttcacca ttaggcatat ctactgtaag agtctttgaa caatcaccct ttatattcac
      661 agttattggt ttatttgtta ccattctaaa agcttcattt acagtattct cttttggttt
      721 aaagtttata atatcattag gacttgctat atttatcata tcagttaatt cctcaacagt
      781 ttttgcttca aacacagttt tttcttgtag acttttaatt tcatcaaaag cttcttcatt
      841 tccatttcca cctacctgtg ttatagtatt taatttttta gtactaagta tgtccctttg
      901 ttttgtgttt aatttattac caaccaaaac aacaggagac tcattttttg cagccaatac
      961 tccaacagct aacgagtcta ttagttgatt ctcattttta ctaccatcct tagttacata
     1021 taaattactt aaatttgtat cagtgtaaaa cttttctatg accttagcat tagtctcatt
     1081 tctatctttc ccactcactc tttctgcatt aggaagactc ttttctacag ctcttgaaac
     1141 agaatttgta cctccaatta catatgcttt tataactttc tcatccctta taaatttatc
     1201 aaatgcttct actccgtcct taggactaga caaaattata ggcatcttat tttgagctgc
     1261 tggtgcccca acgctaacag catcactcaa tcctttttca ccatttacta cagcaacttc
     1321 cttaatatct tttatatcct taagcttatt agccaaaatc agtgaagttt catatctatc
     1381 cttaccatta attctttcta cattaagtcc attacttttt aacttgttct ctatatcttt
     1441 attaagtaca gcagtacctc ctatcaaata aatatcttta gctcctagac gttttatctc
     1501 tttttcagtc ctatcatcta gcttatcact ttctgtcaaa agtattggtg ctcctttagc
     1561 ctttgcaaat ggtgtagctg aaagtgcatc agctaatgaa ttgtcattaa ctagcactac
     1621 attaggacta gaactgtatg ccttttgact tatctttaca gcagtttcat atctaccatt
     1681 acctattaat ttttcctctg taagtgcata tgatggtatt atagaaatgc tacttaaagt
     1741 aagcgctatt gtcagtattg ttaaaatagt ttttggtgct ttcattatta ttccccctta
     1801 ttttgtttaa aatcttacta tatttatatt ataaaataac tttacactat tttacagttt
     1861 aaaattatta catttttcat caataataag aaaactatct aaaaatatag acaatcctat
     1921 ttttcattat ttaaatgata aaaatataaa acaacaaaaa agagtgcctc atgaactaaa
     1981 aagttcattt tgagacaccc cgttttgtta ttttatattt ataaacttct attgaatatt
     2041 ttttaataat aaaatgtata tccttactat ctttccattc actattttcc taaaagagta
     2101 tttagttcat taaaagcatt ttcatttcca tttccaccaa ctctaatagg agtttctatt
     2161 ttcttagact taagtacatt tttttgactt tcatctaact tatttccaac taaaactact
     2221 ggtgaatcag ttttagcacc taatgctcct actgctagtc catctatcaa gtctccttga
     2281 ctctttgaac catctttaac aacaaaagca tatttcaaat ctgagctagg atagaattta
     2341 tctattatct tagcattagt ttcatttcta ttacttcctg caagtcttgt tggatttgaa
     2401 agcttacttt ctaaatttga tgataaagta gctgttccac caattatata agacttagtt
     2461 attttagatg aatttaaaaa ctcatcagca ccttgcaact cactcttttc attagtaagt
     2521 attattggca tattgttatc agcagctgct gcaccaacac ttattgcatc tgcaagtcca
     2581 tttacaccat ttgccactgc aacttgtgaa acagatttta tactatttaa cttttgagct
     2641 agagatatac tggtcttgta tctatcacta cctgaaattc tttctactga tatacccata
     2701 ttactaagtt gagtttgtac attcttgctt aaagaatttt ctccacctat tagataaact
     2761 tttttagttc ctaatctttg taactctgcc ttagtttttg aatctaagtt atcttttcct
     2821 gtcaaaagaa ttggagagtc aattgctgct gtaaatggtg tagctgttaa agcatccact
     2881 attgcatctc catttactaa tactgcattt tgtgaagaag tccatccttt ttgactaact
     2941 ttaactgctg tttcatatct atctgctcca gttaaagatt ctcctgaagt agcttgtcca
     3001 gaagatgttt ttgttatagc ttttataaca aagttacaag gagaaaattc actatatgta
     3061 tttatatctt caaatttatt gttttgaagt atgtagcttt cacctaagtt tgctttagcc
     3121 tcatatagat agtatccatc tatatcagtt tcatatgcta aagttgattt ttctctatta
     3181 ggatttgctg tgttgtctat aactactact attgctcctt taccttttgg taagctgtaa
     3241 gaattagtag gtacatttat gtatccagaa tatgatactg ttccacttgc aagttttgtc
     3301 attgaattgt tttgaggaac tccatttact actggtgcat aatatacttc atattttgct
     3361 cctacagaat ctgtttcaaa cataacagag tcaagttttt cagaatctct gctaaaatca
     3421 aatacatttg ctgctgttac tttatttgac attatcttgc taagaccagc atattcaagt
     3481 tggtacattt ttttatcgct atctggtttt gatactgatt tcattgcgta gttatctgta
     3541 tcttttaaaa gagttttgtc ttcataagaa atccagaaaa agcctttttc tgagttaaat
     3601 tctccccaac tactttttac taaccatgct ccatttgatt ctggtctaac acttggtttg
     3661 aacttatctt ttgaataatt atcatcccat cctacaattg aaacagaatg atttaaaggt
     3721 tcacttttat cattacaatt atacgaattt tcatcatcac ttaagtaggc tgaatagtgt
     3781 gcatatcctg atgtcactgc accatattgc attattgcat ttttaacaga agttttatct
     3841 ttactaattc ttacaacatc tgttacatta aattgtgtag gtgcagtatc catattttga
     3901 ggcctagttg ctccttcatc ttctgattta aaattatatg gaatgtcttt ttccagctta
     3961 ggtcctgccc aggctgtaag atatccaatt gcagttacat tcgaactacc tgtcatatca
     4021 gttaagttcc atccatgtat tcctccagtt gaccaccatc taaaatgctc ttctgaaaga
     4081 tcataagttc cataaccttt taatttcaaa tatgcttcta gtgttgacat tccagaaaaa
     4141 gcccaacatg tattaagttt tccttggtct tttgctggtg tagttaaatc taattttctt
     4201 ggatcatatg atacacttga tttatatgat gctggaagac tacttcttac attagtttta
     4261 agtgttgttc cttccatttc ataaggagtt ggtattactc cattatattt tgctatatct
     4321 ccatttttta catcttccaa gtattgaaga tatgattcag aatactctgc agtttctact
     4381 ccagtcagaa ttttattttt ttctgctgag acaggtattg ttgacacaat taaaaaacaa
     4441 actgtcaaca acaccagtag ctttgacaat ttttttaatt tatactttct catatttacc
     4501 cccttgtatg tatttaattt ttattatatc agatttctaa atctaggtca tattttattt
     4561 ttataaaaat aggaattata attatacata tataaaatac tattttatac tgcatattta
     4621 ttgattaata tgtggtatac taattacata ataatatata ccaaataatg gaggaaaatt
     4681 ttttgatatt aaaaaaacat ctagaaacaa tattatatct tttttttggt gctttaacag
     4741 ttttaataaa cattattact tacctatttt ttacaagaat tattaatttt acttttttat
     4801 tatcaaactc tctatcttgg tctatagcag ttttattttc atatataaca aacaaatttt
     4861 ttgtattcaa aagtgaaaaa actgagtttt tatttctatt aaaagaattt gtatcttttt
     4921 tatcttgtcg tttattttct ggttttatag aaatattact tatgtattta atgattgatt
     4981 tattttcttt aaatgatatc ttagtaaaaa taggcactaa tataattgtg ataattttaa
     5041 acttcgtctt cagcaaggta gtagttttta agcatagaaa ttaacattat tatatttatc
     5101 tttatgcaga ataaggagtt gcctaaaaaa aacaactcct tattagcttt aagaaacaat
     5161 ttctatttta tctgttgctc cccatttttc aactttatta ttttctcctg atgctaattc
     5221 tacataaagt ccatttacct tatttccttc taaaattata tcactattag aagtactttt
     5281 ccaactggag tctatttcat ctcctacatt catagcttct ggttttgtag tctttattct
     5341 atagtaaact ttattaccat tgtatccagt tacactaata gttactttag aattttcatc
     5401 aacagaaaca gttgatttta ttccatttgc tactatttta aaaccatcat ctgtcgcacc
     5461 agctcttccc catcttgaaa ctttctttct tgtataatca atttcaacaa cttctatata
     5521 tgatccattc ttagcattta cttttaatgg ttccgtatct tcaaccaagt cccaatcatt
     5581 tatgttaatt ctatcaccaa ccctcatagc tgatggttta tatgacaaaa ctctataata
     5641 aattttataa tttgaatttt taggtttctg aggtacagtt aacataattt gattattctc
     5701 aagaggagaa catgcactta tctttggaga taatcctgct gctgtatcac tatcatcatc
     5761 tttatctgta ttattagtgt taggtttatt gccacttatt cctggttctt tatttccact
     5821 aacagtatca atctttcccg aatttcttat attagtactt gaagaatcat tatctatctt
     5881 tgttatagtt ccatcatttc ttatatttac atcttttgca gaactaaata ttgttacaat
     5941 ccatatttgt ccattatttt cattttcaat cttgcaacca ttatcatcag aaatgtccat
     6001 ttgatttata tatcctgaat tagttaaagt tccatctttt atatctttaa gtatcaatgt
     6061 tttacttata tcacctgtat tattcaactc tccatttggc atatttatag ttattgactg
     6121 actatattct ccatataaat caacctttat agctttttca gtctctaatt taaaagattc
     6181 acttattttt ttatcaggtc taaactttat aatatcatta gcatccactt tctttaaagc
     6241 agaatccaat tcttcaattg tttcaactgt atatttagtt tcttcttgca tatccaatat
     6301 atctttatag acattttcat ttcctattcc accaacctga gtaactgtac taaatatctt
     6361 agtatttagt acatctttct gaatagaatc aattttattt cctactaata ccactggaga
     6421 attgtttttt gcagccaaca ctccaactga tagtgaatct attaaatcac tttgtttttt
     6481 cattccatcc ttggttatat atgcatttct taaatctgtt tctttataaa attcttttat
     6541 aacattagca tttgtttcat ttctattatt tcctgatatc ctcttagaat ttggtaaatt
     6601 tttttctatt tcattagaaa tggaatttaa tcctccaata atataagaat tttttatatt
     6661 ttgggctttt ataaatttat tagctacttc aactccaagg tttgaatctg aaagtataat
     6721 tggcatgtaa ttttgagctg ctattgaacc aacacttaca gcatctgcta atcccttttc
     6781 tccatttact acaattatat cagaaatatc tttttcatta ttcaattttt cagccaattt
     6841 taaggatgtt tcatatctat cattcccaaa aattctttca actgttattt tctctgattt
     6901 taattcattt tctacattta cacctagtgc atttgaacct cctactaaaa atacattttt
     6961 tactccaagc ctttttagtt ctgattttgt cctaaaatcc aattctttac ttccagatag
     7021 taaaataggt gcatctttca atttagcaaa tggagttgca gataatgcat ctgctattga
     7081 gttatcattc actaatacag cattatcaga tcttaaccaa ccgttttggc ttatttttat
     7141 tgctgtttcc catctacctg aacctattaa actgtcttta ttagatgcat ttaccacatt
     7201 actaggtaaa acaattgata aaaatgctgc tgttaataaa gatattattt tttttgatat
     7261 ttgcattaat tatctcctcc taatttaaat ataattttat ggagcatgta catactgtgt
     7321 tttatttaat tctaaatcat caaaatgaga ttttactgaa tggtatccta tagcataatg
     7381 tccactttca ggattccatt tcttatatgc attcatcgca cttaataact tctcctcttg
     7441 actaggtaat accttccaga cttctacatt tggattaact tttttaaaat ccttatagtc
     7501 atatggttct acataaaatc ttaaatcttt tatttttcct tctctatata actctagtgc
     7561 agcttctcct aatgctctat gatcttcatg tattccacta gctttaaacg gagtaacagt
     7621 ttttactttt gcttctggat attcttctaa gtatttaagt attatttcct ttgccttttc
     7681 tttgcttaac tcaccatcat gagctctatt atcttctata tgtatattac tttcttttac
     7741 acccattgct tcacagctat ccttaaattc ttcatctcta tcttttgaaa attcactttc
     7801 tgataaagag tatttatgaa catctttaat atgataagaa catgaccctc catcatccaa
     7861 aacttttctt attatagatt tactaccatc tgtgcacaat atgacatgtg tatcactttt
     7921 ttcaacatgt tcaattatag cacttcccat acttaaggtt tcatcatctt gatgtggtgt
     7981 aaaaaacaaa gttgcatcta ccactactac atcctcctac tttataaaat gttataattt
     8041 acaataaata gcataattat agaaaaagat tcctgtatta attaaggaat cttctccaca
     8101 gtataagtta ttaccaacct agtattttag ctatcttttg tattactgtc aattcaactc
     8161 cattacctat ttgagttact tctgcaccaa gatttaattt tttactaagt gcattctttt
     8221 gtgagtctgt tatatcagtt ttagctagaa gtattggacc tttacctgct gctagaggtc
     8281 ctgctgccaa tgcatctact agcataccat tatttccata tccatctttt gctatatata
     8341 gtttatctaa tttgccataa tatgtttcta taactttagc attagtatcg tgtcttgttt
     8401 ctccttcaac tctttgaact tttctatctt tatcaatatc tgcaagttga ttttcaattt
     8461 ggctagatac attattagag ccaccaacta tgccaatctc ttttccatcc atcaatttga
     8521 tagcatctgc tgatagatca ttccaaccat ttactattat aggagcctta agttcagcag
     8581 ctttagcagc tatactcata gcatcagcct ccccttttgc gcctactaca aatgcatctt
     8641 taaaagaccc catagctttt gctactgcta cagaagtcat atgtctatca tctccagcta
     8701 gtctttcaac attcttagtt actgattcta attgcttttt agctgtattt gatactgctg
     8761 attctccacc tactatatat attttagctg atgggctttt cttaattata tcttttatat
     8821 aatctaaagt tacttttggt atttcattat cagatgctaa taatataggt gcttttttag
     8881 attgagcaag tggtgtagct gctaatccgt caactagttt atttgaatta actataacta
     8941 tattgtcagt atattttgtt tgttttgcta tagccactgc agttgcatat ctatcatctc
     9001 cagctatcaa tttaaccttt gaattacctt ctaatgcagc tttggcatct tttaaatctt
     9061 tttcattggt actttctaca gtaagctctg ttgcttttcc agatgcatca gtatacttaa
     9121 tagtaaattt atattttcct gtttctgaat cttttgctga aatatcacta attgactttg
     9181 atgtaccatt tgctaccata ttacctttaa cagtcaatct atatccatca tataaatctt
     9241 gtggtgaaac tgtatttagg tcactatttt ttatagttat ttcggccaat tggacatcat
     9301 caatattttt agctcctgct acacctagtt tatcgatttt atttactcta aatccttctg
     9361 cagaagggtc taaatttgtt ccagttgaat caactggatt tgctgttaaa tcaacttttt
     9421 catcaccaat acctacatat atagttttag aagttactgt ttctgtttta tctcttaaag
     9481 ttataactaa cttatcttta gcactatcat atgaagcttt tacatctgca actttataaa
     9541 ttccattggt ttcagtttta gctttttctg ttatagaatt agcctcagcg gaaaggtctg
     9601 ctgaattttc atatttttca gttgcttctg caactacttc atttgcacta tttgttatat
     9661 gtcctttatc tgttatagtt acaataagtt ctttattttc tcccaaagca tttactaatt
     9721 tctctaattc atctatatta gttattattt ttaattttga taaagtctca ccaactttta
     9781 tttcatatat tggttgtcca acttgagaac ctcctgtata cttttgagac attaaacctc
     9841 taactttcga aactaattct gtagcctctt tcttagttat tgtttctttt tttacctgtg
     9901 tagtttctgc agcaaaaact ggagctactg atgtacttat cattgcagca gccataatta
     9961 cagaaagatt ttttttattc atggtatttt ccccctaaaa aattcaaatt tttattattt
    10021 tttccttatt taccaattat aatatatatt tgatattatt tcaataaatg agacttattg
    10081 taataattaa ccaaaagata taaacttttt cttatatttt atttttttaa tatttacgta
    10141 tacaaaaaag taacaaaatt gtaatttttt ttaataatcc agtttataac taatagactt
    10201 ttcatcttct ttatagtata atattaaatg gaagaaagaa atttcaagca tctctttttt
    10261 ccgtatttct cacatagaaa aagaggctga ttatcagcct ctttttccta tacagtttaa
    10321 atttcttaat taaatttata taaatactgt atagtcgtct ctcttatatt tttatttaat
    10381 gattcaaaca tctcataacc ttccatagca tattctttga aaggatcttt ttgagcatat
    10441 gatttaaatc ctacatattg ttttaattgc tccatagcat ctatatgttc tacccaatat
    10501 tgatcaacta cttttaaaag aacaattttt tccatttcgg ttattttgtc aaggcctact
    10561 accatctttt ttaaatcata aactcttttt gatatttcat aagtactatc aattatatcc
    10621 tcaatacttt tattatctaa gtcaggtatt agtaaggtat cagctggcat aaatgtatta
    10681 taaagatgct taaaatatcc atagtaatcc ctctttcttt ttgttaaata ttcagcagca
    10741 gcttctttta ttatatcttt aaccatgttt tgaatatcta cttgtatatc ttcatcattt
    10801 agaactttat ttctttcgtt atagattact tttctttgtt catttatagt atcatcatat
    10861 ttaagaacat ttttccttaa ttcaaaattt ttaccttcca cccctttttg agctctctct
    10921 attgcctttg taagagattt actttcaata gaattatttt tatttgaatt tggtcgtttc
    10981 attagtttct ctatactttt tccaccatac aatttgatta catcatcttc aagactaaca
    11041 aaaaaccttg atgttcctgg atcaccttga cgtccagaac gccctctaag ctgattatcg
    11101 attcttctag attcatgtct ctcagttcct attacataaa gtcctcctaa ttcctttact
    11161 ctactttctt cttctttatc acctgctcct aaagcaatat ctgttcctct acctgccata
    11221 ttagttgcaa tagttactga acccaactta ccagcctttg acactatcaa tgcttcttta
    11281 tcattttcct tagcatttag aacttgatgt tttattcctt ctttcttaag cataccagat
    11341 aacatttctg atttctcaac agaaacagta ccaataagaa ttggctgttt tgttttatgt
    11401 atccttatta cttcttctac aacagcttga tacttttctt tctctgttct aaacacttta
    11461 tcatgaagat ctgctcttat aattggtttg ttagtaggaa tttgtacaac atttaattta
    11521 taaattgatt caaattctcc ttcttcagtt ttagcagtcc ctgtcatacc agaaagttta
    11581 ttatataatc taaagaaatt ctggaatgta attgtagcca tagttttaga ttcatctttt
    11641 atttctaccc cttcttttgc ttctatagct tggtgtaagc catctgtata tcttcttcca
    11701 tccattactc ttcctgtaaa ttcatcaact atcattactt cttgattaac aacaacataa
    11761 tcaacatctt tttccataag tttgtgaccc ctaagagcct gatttatatg atgatataat
    11821 tctatatttt ctatatctgt aagattttta atcccaaaaa atgattctgc cttatcaata
    11881 ccactttcct ttagagctac ggtcttatct tttctatcta attcataatc ttcttctttt
    11941 attgttttta taaatgaatt tgctaattca taaagttttg aatcttcatc accctctcca
    12001 gcaattataa gtggagttct agcttcatct ataagaattg agtcaacctc atcaactatg
    12061 gcaaaattca actctctttg tactttatca aactttttag ttaccatatt atcttttaaa
    12121 taatcaaatc caaattcatt atttgtacca taagtaatat cacaattgta ttgaactttt
    12181 ctaacttcag gtataagatc tgcaataatt actcctacag acatacctaa aaactcatac
    12241 actggttgca ttagctcttt atcacgttgt gctagatagt catttactgt aacaacatgc
    12301 acacctttac ctgttaaagc atttagataa acaggtgcaa cttctaccaa agttttacct
    12361 tcaccagttt tcatttctgc tatttttcct tgatgaatta caatgcctcc aattaattga
    12421 accctatatt gacgcattcc taaaactctt tttgaagctt ctcttgccac tgcaaatgct
    12481 tctggtaata aactatctaa agtttctcct ttttttaatc tatctctaaa taggtctgtc
    12541 atttttttta attcgtcatc agacatattt tctatatctt tttctaaaga ttctatttta
    12601 tcaactatca cattaagcct tcttatttcc tgctcatctg ctttatccaa tattgtatcc
    12661 aaaactgaca tatttaattt acctcctttt ttatcataca attactatta taccttaaaa
    12721 ttatagaata gtagacaatt atttttattt atagtataat aatcatactt aaataaatta
    12781 catctttaat tatttaggta tttctcacaa aaaaaggaac tatttttagt tcctttttta
    12841 atttcttttt ataaaaaaga gaacttcttc aaagaagttc cctcttattt atagtttaat
    12901 tttatcttat aattctaata aatcttttat tctcttaata actgaatctg ctattccttt
    12961 accaacttga gtcaatttct tagaatcatc agaatttgta actttactta ttgctactga
    13021 ttggtcagaa gataaactat cagttgctaa aactattgga gcttcattgt gacctgctac
    13081 tgctgctatt gctaacgcat ctactaattg atcttctttt gtagaaccat ctttagcaac
    13141 atagaagttt ttaacacctg tgctaattac actgtcacta ttatcttttt caaaataagt
    13201 ttttataact tctgcattag tatcttgtct atcatctcca ctaactcttt ctggactctt
    13261 acctgtagca tcatctatag catcttccat gtcttcagaa acactagatt ttccacctat
    13321 tatatctaca taagcacttc ctataaagtc ttttgcatca gttgataaat cttttccttt
    13381 tccatcaact actactattg gcatttcttt attagaagca actgatgcta tactcattgc
    13441 atctgctaat ccagtaccac caactacaaa tactttatta tggtttaaac ctatttcatc
    13501 agcaatttct aaagatgtag catatctatc atcaccagat aatctttcaa cttttaatcc
    13561 catatctttt aattcatttg ctacttcttt agatacagaa ttttccccac cagctatata
    13621 aacagtcttt ttagatgtta taccagtttt atcatctaat cccattactc tctttatttc
    13681 agattttact gatgaatcta acttatcttt tgaagttaat aataatggag catctttaac
    13741 agcagctaaa ggtgaagcta ctagaccatc tactattgat tgtgatccta ctaatactac
    13801 ctcattagct tctacataat ctcctttaat tcctccatct gcattataag agtctttact
    13861 tatttctatt gcagtctcta ttctatcatc accagctaat acagaattat ttgaataaga
    13921 attattataa gttcttaatt catctaaagc tgattttaag ttattcttat tagtagatct
    13981 taatgttatt atagcaggag tatctactct atcacttgta ggtaattctg gcttatagtt
    14041 agatgatgca tatgttgaag ctgtatttaa tcttttacct gttggataaa gaactacctc
    14101 ataataatca ttgtcagttt tttcaaaatc acttgctgtt actgtcttat atgcatcttc
    14161 taattcagta tctttaaata catatttttt agctaaagct tctgcttttt cttttgcatc
    14221 tccagatatt gtaactgttt catctgatgc tgctataact gttacatttg attcaactgc
    14281 tccaactttt tctccagttt tttcaaaact taattttgat gtaccatcag tagtattaac
    14341 cgttataact ggtttactaa aatcatatat ctctttagta ccatcaagag atgctactgc
    14401 tgtatctaaa gtaggtgcta ctgctgcttg tgtatcatat tttaatttaa ttgcaccagc
    14461 tactgcatca gcatatgttg ctgtaatagc tactgttcct gtagcattat taccagtctt
    14521 atcagtaaat tttgaagttt tgactgctgc ctttgtagct gctaaaactt catctttagt
    14581 agctccatct acataagctg acgtagttgt atcatatttt tgtaacttta atttagcatc
    14641 attttctatt gaatttccat cttgatctac aatcttaact gttgttgcag taccaacttt
    14701 agtaactaca gcattactat caagttcctt taataatgta tcatcatatt ttttttctgt
    14761 tccatctgta atttttacag atatttttgc atattctcca gcttttaaat ctttaatttc
    14821 atctttaaca taacttattt gacttgcttc taaacttgat atagataccc cttttggatt
    14881 tccttttttg tcaaaaaagt taactgttat gcctgttaca ccatctgcaa catatttttt
    14941 aagtattctt tctatatcac tatacttact actagataca gtggtatttc catttggaaa
    15001 actatcctct gctgcagcga aaactggtgc tgctgatccg attactgtaa cggcagacat
    15061 tacaactgcc aaatttttct tattcattcc ttaaattcct cccaacatta tattaattac
    15121 atctctttaa ttatgtacat taaaattcca tgttcatata aaccaaatat ttctcacact
    15181 cttatgatag actatataaa atagaatttc aataatttat gcaaaattaa tagaattttc
    15241 tttcaacatt tttccccttt tttttgctat ttcatatttt ttaaattaaa ttttcaattt
    15301 taattttatt aatacattta tttatctgat ttaatcaata tatattaata ttttctacca
    15361 taaaatatta atatatactc taactattta aaaattccat tgtagcatta acttctcttt
    15421 gattagaaac atacattcca aagccaaaac tataaaactc ttcctttaac atattatcat
    15481 tatacttaga agacttcttc cataaatcaa atacagactt agcaatctct tttgcatctt
    15541 tagatgtata tacagactta acattcatag gtaaatatgc aatattttca tcagttctca
    15601 ttccaaagcc agaaaatact tcagctgcat ttttcccatc tatttcatga gcaaatatct
    15661 tcttctcatc catatactta gaccatgcat ttgccattcc agctaaagaa tctaattctc
    15721 ttaaactttt cttacctttt tcttttctat atgaattaac tagattatac atttcattag
    15781 ataccatagc cttaaactca taactattag ggtcttttgt acttgtgttt ataattactt
    15841 tgacatttac attaatctca cacttttgcc caaaattatc aaaagcactt acatttaaaa
    15901 catacgttcc tgccttactg gtatccacag ttccctcaat attaggcttc aaattatttc
    15961 cataataatc agtggcaact atattcaaca tactattatc aaacttatcc cctacagaaa
    16021 tctctacatc attagcagtg attgtaggca ttgtattttt atcagatgca gaactaatac
    16081 attggtcagc aaccttctta tccattccac ctaaagaagt aacttcatca gcacctctaa
    16141 gcacactctt atcacttcca tcattaacaa gtactatagg tttgtcctta gccaacggag
    16201 aaccagccac agcatcaact aacttatacc cttgagaaac ataaaacttc tttgttcctt
    16261 tataaaagcg ttgtataacc ttcttattag tttcaaatct atctttacca gcaatcctaa
    16321 cagaattagt cttactcaca agttcattac tcattatctc ctctgaccca agagaataac
    16381 attgaacgcc atcaacctta aatggtatac tctttccatc agtaagtata acaggaactc
    16441 catctctagc agctacagaa gatacactca ttgcatcagc ctcacctgtg tatccattta
    16501 caagaaaaac cttatcacca tcatttactg gtttaatagc tgaaatctcc ttagctataa
    16561 gatagctagt ctttattcta tcttccccac caattctttt aacttcaatc cctttattct
    16621 taagttgatt ttctacagat ttacctattg tatcctctgt acctataaca taagcattct
    16681 taacatcctt tagtcttttt tcaacatctg ttggtatctt atctctttgc actaacatta
    16741 taggagcttt tacaactcca gataatccac ttgcacttaa tccatctact atagaattat
    16801 cagtatttac taatatgact gtatcatata tttgtttatc tgctatcaat gcagaagtct
    16861 catatctatc tttcccttgt atcttttcta tactcgaaag tgcattgata tttggtgctc
    16921 ctgccattat taatgatatt gtcaatccta ttgataatac tctcttattt accttcatcg
    16981 aactcctcct actaattttt ttatataatt cagctaatca taaattacac cctcagtagt
    17041 gattccctca aaatttataa actactaaaa caaaaaacac ctaaaatacc ataacctgta
    17101 aagcaataat aaaacagatt acaaaaagta ctttagatgt gattttcatt ttataatatc
    17161 agtaaattaa caaaaaaaca agatttatgg aattttttac aagctacctt cattgccatt
    17221 taaaaactct tgagtagcat gcacttgacc atcagataat atataaagcc caaatccagt
    17281 actataaaac tcatcactaa gcatgtttgc attgtattct ggagatttct tccacacttc
    17341 aaatatagcc tttgccaagt cttttgcatc ttgagttgtt tgaacactct tagaatctat
    17401 ataaatatat gctatatttt cctcacttct cattccaaac tcagaaaata cttgtggagc
    17461 atttttgcca tctatataat gttcaaaaac tttgttatcc atcatatact tagaccatgc
    17521 atttgccata ccttctagct tactagatac taccaaaggc tctttacctt tttcttttct
    17581 ataggaattg attaagttat acatttcagt agataccatt tttttaaatt ctgggctgtt
    17641 gtaatcatga gatttatcat ccaacacttt tatttctact ctttttcctg tactttttcc
    17701 ccattcgtct gtagctttta atgtcaatat gtatgtacct actctatttg tatctataaa
    17761 cccatcaact tctattggta ataccttccc agtgttatct ttagctacta tatttaactt
    17821 gccagtgtca aacttttcac ccttatatac ctctgtactt ccaactgtaa ttgctggggg
    17881 ttgtccattt gactttgaag cacttataca ttgttgtatt accttctcat ctatttcacc
    17941 tacagaggtt atattcttag ctccttctaa tacagtttta tcgcttccat catttactag
    18001 taccattgga gagtttttag taagtggtgc agctgctatt gcatctacta attggtatcc
    18061 atctgataca tagaatccat ctgcactatt aaaaaagtag tctattacgt ttttgttagt
    18121 ttcaaatcgg tcagttcctt ctattcttac tgagtttgta tttttaacta gaggattact
    18181 cattatctcc tctgaaccta tacaatatga ttgaatattt tttacatcaa aaggcacact
    18241 ctttccatct gtaagtatga ttggagctcc atctctagta gctactgatg atacactcat
    18301 tgcatctgct tctccactat atgcattagt tagtagtact ttatcaactt tttttatagt
    18361 tgctatttct ttagctatta aatagcttgt ttttagtcta tcttctccac caattctttt
    18421 gacttctata tttttagaat ctagttcttt ttctactgat ttacttatag tatcttctgt
    18481 acctattata tatgcttttt tgatattttt tagacatcta tttgtgtctg ctggtatctt
    18541 attttgttgt gtaaatagta ttggagcttt tgtagctccc gataatccac ttgcacttaa
    18601 tccatctgca agtgattttt ctgtatttac taaaattact gtttcataag tctgtttatc
    18661 agctatcttt gctgctgttt catatctatc tttaccgtat attttttcta ctactgatga
    18721 tgcatttaca cttttgaagt ttactaagat taatgatact gctagaccta atgataatat
    18781 ttttttgttc attttcatat ccccctgatg atttttatat tttatattta tattgtgatt
    18841 attttccatt tattttctct ttattttcca tatattatag agtatatatg atatgaatat
    18901 atctcgtcta tatattagtg ttttatttta ttaaatttaa aaaattattt ttaacttctt
    18961 tttaaacata ttcaaaattg aatttatatt tatatatata aaagatatct gctttattta
    19021 aaattaaact taatatagct caaattatta tacattttaa cctcaatatt attagattgt
    19081 taagataatg aaaataaaat aagaatgcat ttaaatatat aactttatat ctaaatacat
    19141 tcttattttc tatttactta atatttattt ttcaattaaa ctcttaatct tgtctattac
    19201 agatgaggct attcctccac ctacttcaaa caactttgat gaatttttac cttttaatga
    19261 cgattcttgt gatttatcta acgtatttgt agcaagtata actggtgaat tgtttttagc
    19321 tgctaatggt ccaactgcta aagcatctat aagtttatct tgatttgcaa ctacaactcc
    19381 atctagctta gattgagagt agaatttatc tattactttg gcattcgtct cttgtctagt
    19441 ttgacctgcc accctattgt ttgatatatc tttgtttgct atttttccaa cttgttcaat
    19501 agccttgtta gatatttttt ctactccacc aataaaatat atatttgaca ccttatttga
    19561 tttaataaat tgttcagctt cattatctac accatctttt tgtgtaagta ctattggagt
    19621 tttttcttta ccagccagtg atgctattga taatgaatca gcttctccat ttcctgctcc
    19681 tatatacaac ttgcttacat tattcgtctt atctatttct tttgctatat taatagaagt
    19741 ttgatatctt gtatctccac ctattctttg tactgatatt tttgaattta cagctttgat
    19801 agcttcaaca actgaatttg gcattgagtt gtttccacct atcacaacta cttttgatgg
    19861 atttagcctt ttcaattctt ctacagtttt ttgaggaagt ttatcatttg atgataaaag
    19921 aatcggtgag ttttttacac tagcaagtgg tgtagctgta agcccatcca ccatactttt
    19981 atcttctcca tttactatta caactgtatc tgattttgtc caaccacttt gagatatttt
    20041 gatagctgtc tcaaatctat catcaccttt taattttttg actgtgacat tagatgtaga
    20101 atcacttgaa tttcctcctc cagagcttcc accactagat gagccgcctg aattacttcc
    20161 tccaccatta tttccaccac taccattatc tggtggtaat tcatccggtt ttgataattc
    20221 attttcaact atgtattcta aactttttgg aagtgtaact tcaacatatt tgtttattgt
    20281 aacttttctt cccttagttg ttttttgtgc taatccaagt tttaatatta catttgaacc
    20341 actttcttgt gtttctttac taacaataga atagtttatc ctaatattgt ttaataaata
    20401 ttcaagtgct tcacttttct ctaccttata cttttcaggg tcatttttac tagaaccagt
    20461 tcccccaatc ggttttactt cactctcatt aataagggta aatattaatc cttcatcaga
    20521 gcttatattt tcataatcca ctgttttgtt gttatatgtt acaattttta aagctggttt
    20581 atcatttgtt ccttttccta aaactttata gtcagcattt gagttacttc cagatttttt
    20641 tacagatatt cttcctatat tcaatctatt tccgtctagt aagtcttcat ttgatgtaac
    20701 atatatatct aatgtagttg tattacttga tttgttgtat tctgctctac aagtagcatt
    20761 tgcatttcca ctttttatct gagattttat attatcagac caagtaatct tttctttctg
    20821 ctcattatct actacttcaa cctcaccttg tacttttata ctggcttgaa atgaatatac
    20881 tatgttttct actgagtcca cagatatatc tatagtattt actttctcat acgtttttgt
    20941 tccttgtaaa actggagctg catatgcaca tgtagcacta ccagttacag ctactgccat
    21001 agttgatact gctatagttc ttataaaaga ttttctttta ctcattaaca cccgtcctta
    21061 tctatcatta actaagtgga taaatttact tatccaccta gcttttatat ttaatttata
    21121 aattacccta aatttatgat tacatttata tactttactt ttaatatcta ctattttaaa
    21181 actattctag tacctaatct tattagatat acaatgttag tgttagtatt tttacgtttt
    21241 tagagttcca cctactattt atctctaaca atattaccct ttactttatt gcttacagtt
    21301 ataaccttct tattactgat atcaatagaa tttcttgtag cttttctagc tttactatta
    21361 ctatcagtaa gacttattgt ctttaactca tcataattct tagctcctac aggtacatac
    21421 attgtatcac ttacaaatct ttgacctact ggagtatctc cttgaaggtc attgtatcta
    21481 tatagttcag ccttaacctt atcacttaaa gaatcaaagt tttcttttgg catatagtaa
    21541 acccatgtac ctttactgat ttcacctagt tcaccttttt ctggaacttc tgcaaataaa
    21601 agtgcttctc cagatatagt cttattgttt ttatctataa gtagtggtaa attaaatgct
    21661 ggatttccac tgtattcacc tgtaataact attgaacccg ctggaatctt acctgtttca
    21721 tcttcacttg tgctagagtc atcactttga tatacataat cttctgctaa ttttccaatt
    21781 ccattagtac gagtttcgtc tgcattattc attgtgccaa tttctatatt atcacctgga
    21841 ggtcctatta tatctaattc tgcaacttct atattagact tattatttga gattagtttt
    21901 acatatctag cttggtatgt ccaaagttta ccatctttat taaatgtaac tctagcttca
    21961 ttatcttggt cttttcctcc accaactaaa tcttgtccat attcaaaagt tccttgactt
    22021 acatcttccc agttcttttt atcattactt acttgtattt tgtaattagt taaaggattg
    22081 tatgttgtgc tagtattctt tctaaagtta aataatcctt ttaatgagaa cttcctagct
    22141 tctgtctctg gttttgtata ttttagtcct actataggta atgtttcttt catgtctact
    22201 attatatatg gattttcctc tacatttata tcagggtctt tttgagggtc tttgttccac
    22261 tctgctttac ttattatctt tcctttatat gtagtatttg catcattatc ttttatatta
    22321 tcaatttcag gattttgtaa tggtccatgt gagtcatttt cagttctaac atcaccgtca
    22381 gaaacagtat ttgttatgaa tgaccatgct gatttattta ttttcccttc atctgataat
    22441 tttacagtac caacttcaaa ttcttctgtt ggatttaggt gataatcata tgcaactacc
    22501 ttatatgtaa atgctctgtt attaagagga gatatattat cagtaaattt agtcttacta
    22561 tttccttttg catccacaaa tccaactgtt ctgtatttta cctgtgttcc attttcacca
    22621 tctaaataat ttccatcact tcttattatt tcgtatccta gtatcttatc tttatcctta
    22681 tctacatcta ggtctataga tattttatta gatttaacta gagaaccact ttgtattcca
    22741 tcagaaaaac tagcacttac tttagtatct tttgccatac tagctatatt ttcatttaaa
    22801 atctttcttc tagcttcgtc atttacatat tgtatctttc ttgattcttt ttcgtagttc
    22861 ttactatcca ttatactgtt taattctggt gtaatttcta ctccccatgc cttaaagtaa
    22921 tctcttaaat ctttttcaac aacacttgat gccattgcta ctagcatttg gtcttttggc
    22981 aaactattaa ttgggtcact acttgaaagt gctctgtatt ttcttgaaat ctttgcatag
    23041 aatgtatcat tacttaaatc agcatctgag ttattcttta acattgaacc cgtaaaatca
    23101 tcatcataag ctagatgtaa ttgccataac attccaagcc tttcaaatac attgcttggt
    23161 atacctaagc tatttgaagt tacatgctca tatatcttat ccattgttga accttcaatt
    23221 cttgaatgtg tcttatcatc aaaggtctga gcaagtaaag caagtacatt gttactagtt
    23281 tcgctatatg tcatctttcc aatatctgta acatgtccta tctcatgacc tattccccat
    23341 ccaaataagt ttcctcctgt agcttttcca ctatcatcta tttggaaagg tactccattc
    23401 ataagccctg gaactgaacc atattctact cctacatgta atccagaagc atacataaat
    23461 gctccaataa acattctttg gtattttatg ttcatacgag attttggagc catatcattt
    23521 ttagttaagt taaattcatt atcatctaca gttccattac catctaaatc ttgtgtttta
    23581 aatactcctc tttctgagta aactaaatcc attatttgtt cccatgcaag catactatta
    23641 tataatctat ctacttgtgt atttaaatca gcatttcctt ttgatatccc ttgatataca
    23701 gctgttgcag gaacatttaa tgttacttta tcactttcaa tatctgtagt gtttaacaca
    23761 ccagtttttt ctgaatatcc atatgaatta ccaacatttg ttcctggata atatggttct
    23821 ccttttacag catctttata tctagctaat tcttctatat atgcttttat ctttttctta
    23881 gattcagaaa ctcccgcagg actcttatca tttattgttc catttagatt aaggtgtggt
    23941 atcttagtag ctcctgctac acgtactttt atatctcctc cacttggagt atcttcagcg
    24001 tatcttatgt ataaacttcc tccacattct atatctaaac tatgaagttt gcttaattga
    24061 attacatttt ttccagtgtt aagatttatt tctccactct tatatgcacc agattctcca
    24121 tagtactgtg tatatatcaa cttaggagtt tttccacttt tacttccaac atatactgtg
    24181 atttcatctc ctgctctagc agctactcct aatgcctgcc agtcattttg catacctaaa
    24241 ttattggaat ttacagtata ctgtccgttt ttatctttat attttcctaa tttatttatt
    24301 tcttgattta cagtagttac atcagtaagt gtggctctat cattatataa gtcttgagct
    24361 aattttaatt ctctctcaat aactgtctta tatggatgat attctccact agctttatct
    24421 ggagtattta atctatcttt taattcagtt attttttctt gagttacatc ttcttttaat
    24481 tcaacttgta ggtcatccat aaatagattt cttacatcat cttctatact gtcatactca
    24541 taaaacttaa gttctgatat attagactta tatgaatagg atgaacaaac acttacttgt
    24601 atcttggtag cagttattgg ttcttttaat ctaaccatta catacttatt attatttaca
    24661 gggtctgtct ttgtttcaaa aggaacatcc cccagattgt gtaattgacc attttcatcc
    24721 caatatcgta cctcaaagtc atttattgtc ttatcagaaa catcaaaacg aggtgtagcc
    24781 ataaaagtat ccatagtata agatttatca aaagttatta ttggtcctct attcgttccc
    24841 tcagctgcat tatatgttgg gaatgtccaa tgtgttgtaa agtccccatc tactacattg
    24901 aatttatcaa atggattttt atcactatat tcacttttgt catatcctgc tggataagta
    24961 acatctacaa tgtgatttgt tggtattcca aatccaccat tctctttagg agtattaatt
    25021 aatctatagt taggtgttgt tggtgcatcc atgctttcag ttgtacctat atatgtttta
    25081 gacattccac tagttcccaa gtggttagta gctgtcattc taacttcata tgttgtatta
    25141 tccttaagac cttctatctt tgaacttgtc ccacgaataa gcttatcatt gtattttatc
    25201 caagacccat tagagccttt ttctttatag tacaagtcaa aatctttagc ttgtttatga
    25261 tttttccagc ttacatcaag agatttaaat ttacctttaa catttatacc ttctggtggt
    25321 tctggttttg tgtctggaac aacttgaaat tctaatatac tatctgggct aaattgtata
    25381 ggtttatagt ttgaatctac attttctggt actccgtcta agttttctgg tgttgcatct
    25441 ttataaccac tagaccaatc tccatttaaa gattgtatgc taaccctata tagtccatat
    25501 gcttctatat ctctaacttc tattgtattt ttactggttt gtaatttttt agtagataat
    25561 acttttccct tactatcaat tttatctagt ataagttcgt atgctgatac atttacttca
    25621 ttattccaat aaaaagatac tttttcattt ccaacagcag tgctagtcga tattttattt
    25681 attttaggta tattcatctc tggctttggt atttctttat atacattgtt taaaaattca
    25741 acttttgata tttctgcaag atttctatcg tttgctgttg tagctgttat ttttatagtt
    25801 atctttttta ctgctacttg tttaccaaga tttattacta tatcactatt ttgaacatct
    25861 gcatatgttt ctaatgttga cttactatat gtagatgttg tagagttatc atctttactg
    25921 atattaccct cttcttttgg agtatcttca tctgaattag gtttatccat tgatgaattt
    25981 tctttatcat tatttttatc ttgattggta ttagagttta cttcttgttt atcgctattt
    26041 tcctgttgtt catcattatt ttcatcttta ttatttgagt tattatcagt ctggtttata
    26101 ttttcatctt tattatttac ttcttcttga tttacttctt cttgttcgtt atttacttcc
    26161 tcttgttgct cctcatcttt taagtttttc atatattctt tgttttcata aggaatctgt
    26221 tgaacattac catctttgtc agtaacctca actattcctt ttgctggagc agtaccttct
    26281 ggagctttta tattgatgac ttccatatta agtgcttctg ataaagctat atccattact
    26341 gctggttttt cctcagatat ttcatcattt tttgaagata ttgtaactcc attattttct
    26401 ccactaaata aattttctac attaccatta atatctacat cactatttcc ttttaattca
    26461 accttacttg tatctactat aggattggta gatactatac tttctaggct ttttgcatct
    26521 tcactttgtc ctaaattttt ctgtacataa tctaagtcaa caatatctac ctttccatct
    26581 ctatttaaat caaattctct tttatttgaa tctatattct ctaaaacctt attataatca
    26641 ctcttatcta ctttaccgtc tccatttaca tcacccatta agaacaattc ataatttaaa
    26701 ggtttatttt tattatctac acttgctcta ttgcttaata agactctttg tgaataactt
    26761 gatatatcaa tgtctttaat ttctttgttc ttaaatccat ctccagagac ttctacattg
    26821 tattttccaa caggtaaatt attaaataca atattataat atgatatatt ctcatcttta
    26881 ttttttattt cacttctact tgcagataat ttttttatag tatattctat attatctgtc
    26941 ccaacattta ctgttcctga atctttttct ccaagcttta ttattccact attgttacta
    27001 tcatctttta atcgtaactg catattagtc atactttctg aatcgctatt ttttattggc
    27061 agtgaaaaat ttaaatctac ttcaagactc ccccttaact tttctgtaac tgatttttca
    27121 actgccctta gcttcccctc taatataggt tctgcaaaaa cgtttagtgg tgcactacac
    27181 atagatactg ctagtacaca agatattgcc tttttcatga aataacaatc ctcccttaat
    27241 aaatatctaa tttttcatga atttaaatac tataagtttc agacaataaa aaaagacact
    27301 caaagagaat cttaattata aaataaaaag actttactct ttttagcaac tggctgatat
    27361 ggctttaaaa gctttaatcc ctatagtttt gcgtcattag atttccctaa ttttgccatt
    27421 taattttcac tactttctta cccattttat actatattta aactttttaa tacaattttt
    27481 ttagattaaa ttataaaaaa ataacattta tattaattta ttaatataaa tgttattttc
    27541 cattataatt taattattta tatagcttcc ttacaagcat aattttgtgt atattttctt
    27601 attctttata tcttccataa aattcatgtg tagcatatag attcttatct cctgttatag
    27661 ctataccaaa tcccattatt tcataccctt tatgcaacat gttagttcct tcttctggat
    27721 ttgtcttcca ctcattaaaa ataaagtttc ctatatcatc tgcatctcta tttgtatata
    27781 caggtttatc tggaatttta tatttaatta tattttcacc ttgaactgct atatatccag
    27841 gtttaatctc actccaatct aagtatttca aaaaagtaga atatgaattt tttccattta
    27901 tcgtatgaga taaagtcttc ttatttgcca ttaaattaga ccaatcattt gctaaaccct
    27961 ctaatctgct tgctacagat aacgctctta ctccattctc ttttctatac tgctttgtaa
    28021 gagcatatac tttacccttt attctctctt taaatgctct atcatttgga ttgtaatata
    28081 aaccttgttg atttggtgaa gcttgattta tacattgctt gataacattc tgatttatgc
    28141 ctcctagtac agtcaatttg tctgcaccac ttaaaatact cttgttactg ccattttcaa
    28201 ctaaaactac aggagcattt tttgctattg tagaggcagc caaagcgtct gttaattgta
    28261 agcctttact tagataaaat tctttactat ttttataaaa ctcttgtata actatcttat
    28321 tagtttcaaa tctatctgtg ccacccaatc taatagaatt tgtgctctta actaattcgt
    28381 cgctgattat ttcactagaa ccaagcgcat aactctttaa gcctgtcgtg tcaaatccca
    28441 cactatttcc atctgtaagt attataggta ctccatctct agcagctact ggtgatgcac
    28501 ttatcgcatc tgcttctcct gtaaatccat tggctataat tactttatct attggcttaa
    28561 tttctttgat tttttcagct atttttatac ttgtatcaaa tctattttca ccaaagattc
    28621 tttgtacaac cttctttttg gatagtaact gattctcaac atttttactt attgttgatt
    28681 ctgagcctat tatatacaca gtctttgctt tgtttaatct ttccatagtt gtgtttggaa
    28741 tctgattttg ttttgtcatc aaaataggcg catttaaggc tccagctaaa ccacttgcac
    28801 ttagaccatc tgctaagcta ttatctgagt tgattagtat tgctgtattg tagttttgct
    28861 tatctgctat ttttgctgct gtctcatatc tgtcattccc ttttatttgc tcaactgatg
    28921 tcaacgcatt taccatagga gtatttacca ttactaaaaa tagtgtaagt cctatagcta
    28981 atatcttttt actattcttc atattatttt ctacccccaa tgtacttttc atatttttta
    29041 ttagtactca tacttatttt taatcaaaag ttacaatttt gttaccatat tttatatatg
    29101 ataccatagt tatccataca actcaaacaa tatacctaaa gtttttattc tctataaatt
    29161 caaaacatta taatttattt tatttaatta agttataagt tcaaaataat ttatgttaat
    29221 aagatgttta atcattataa gaagtatctt tttataataa tttttgcaat atgaatttct
    29281 caacattata atcaaaaaat aaaataaggt atctcaatct aattctaaat gagacacctt
    29341 atttttatta ttttatcttg ttatttgtat attttataat atctacacta tgtcttacat
    29401 attaacgcat tgtataatca tatattatct aaacaaactt ttaatattaa ttcctatatc
    29461 ttattagttc ttagtaaata agtttatttt ttctgctatt ttttcaatag cgtttttagc
    29521 tattccttca cctatttgta ctaacttagt agcattctta agtcttaact caactacttc
    29581 ttcttgtgat ttagaaagtt cttctgtagt taatactatt ggagcctttg aactagctgc
    29641 aagtggtgct gctgtaagtg catcaactaa ttgtccattt ccacctacat aaccatcttt
    29701 tgctacatat gctttagttg cacctgcata gtatttattg attactttag cattagtatc
    29761 ttttctattt tctccagcta atctttcaac tttattattt aaatctatat caactaattt
    29821 gtcttcaact tcttttgata cagaattttc tccacccact atttctaatt cttttccttt
    29881 taataatttt tcagcatttg catctaattc gttacctgta actattattg gagcaccaaa
    29941 ttgagcagct ctagctgata tactcatagc atcagcttct ccatttccac ctactacaaa
    30001 agcagtctta aatgtatctt ttaattgttt tgctatttct aaagaagttt caaatctatc
    30061 ttctccagaa actctctcaa ctttacttac acctaattta gaaagttttt cttcagtttc
    30121 ttttgatact ttagattctc cacctactat atatattttc ttagaagata gattacttcc
    30181 aagtactctt aatatttcag cttctatttc tgatggtagt gaatcttttt tagataataa
    30241 tattggtgca tttttttgag aggcaagtgg tgctgatgct aatccatcaa ctatagcatc
    30301 ttctccaact aaaattatag cttctgcttc tccatctttg aatctctctt tactaacttc
    30361 tactgctgtt gtaaatcttg aatcaccaga taaaacttct acttttaatt cttttccacc
    30421 ttttacatca gttaatactt tgtgtaagtc tctaactaac ttatggtttt tacttgaaac
    30481 acttattgtt tctggctttt catttgcctt gcttaaaact atatcaaagc ttgatttttc
    30541 tggtttatct ttatcatcac tatcttcttg ttcttgagta aggattgctt cattttcaaa
    30601 tgttaaagca tatccatttt taactttatt aactatttct cttcctaatg tagttaatct
    30661 aattccatca aataattctt ctgctgatat gtcttgtaaa tctgcgtttt taactgttat
    30721 cgtatgtaat tcttttgaat ctatgtcact ataactcttt tcataacctt caaaagtacc
    30781 ttcttctgat gttatcactt ttgagaaatc taaatgttgg tctcctacat ttaatgtaat
    30841 aacatttgct gaatcttttg ctctttttac ttcaactgta tttgtagatt ttatagttgc
    30901 tgttaacttg ttatcagaat cttctgctaa agttgcattg taagcattaa ctgcatctac
    30961 tatttcttga gcagttttgt agttttcaat tttatagtca actacttttc cacctaacac
    31021 ttgatgtcct ttatcttgaa tagtaacttt taaactttgc ccttctgtta aagagtttat
    31081 cttattttgt aattgagttg cattagttaa gtttacattg tctactttta tatcgtaaac
    31141 tctatcattt acatttgctc ctgcttttgt atcttcaaac ttaacttcta atgcttttct
    31201 aacctcttcg attagtttag cagaatcttt cgcacttact gtgtaatttt tatcaacatt
    31261 ttctgtcaca gtattgtctg cgaatattgg tgctgctgca ctcataactg tagcacctgc
    31321 cattactatt gccatacttc tctttttgtt gcttaacata tttatgtcct ccgaatatta
    31381 ttttttattt tttatattcg tatttcccac acataaataa tattatatat aatattattt
    31441 ttcaatatat tttatgtgtt tacataattt actaacacaa acactaataa tatcttcttg
    31501 aaccccttcc ccctgcttag ctctctataa ttatgctcaa agatagaaat cctattttat
    31561 agtgattttc tactaaacaa tcatatacta acaaaagtat tcaaactcca tttttatata
    31621 ctactatgca ctaatttttg ctttactctt attacttaaa tatatatcac taaattaata
    31681 tctatctcca tatattaaaa tatataacat attataaaaa tcatcataaa ttagagttta
    31741 aaattaaaaa ttattctaat acatgtaatt gataaaaaat aaaatataag agtagctact
    31801 ttaaaataaa tgctcttata tgattagata tttttgcata attaaacgat aagaaatcaa
    31861 atttaatttt acataaatag aatatatatt tttatataat aattgaaaat aaaagaggat
    31921 acctcataat gataaaagaa tcactttgag ataccctctt acaaacaact aaatcaataa
    31981 ttttctatct ttcacactct tgatttgcaa ctgtacaaga agttttacaa gctgattgac
    32041 aagaagtttg acactctcca catccacctt ttgcagcact ttgctttaaa gtagcttgag
    32101 ataaagtttt tacatgttta ttttccattt tcaacgcctc catttctaat tgtttcctat
    32161 tgattatatc ataaaactac tttaatataa actctattta aagttgacac ccaatacgcc
    32221 tccaatgcct cctgctgctg atattaacaa taacttataa atcatcccta cttcaaatac
    32281 aaacttttct tgtgctaaaa acacagtcaa aaaaatacat actatgtaca aaagtcctac
    32341 taaaagccca tacataagtc ctttttcttt catgtgtttt gaagtgtaaa accctcctat
    32401 agctgcagaa atagtagtta taaatgatga gaccatagtt atattatctc caccaatatc
    32461 tgtaaatgtc aaaaataagt tatacactaa taaaacagcc aaagttatta tatatgcata
    32521 tcctagacct ttaaaaatat aattagattt tcccataaaa aaacctcctc tcaaattaat
    32581 atatattcga gaaaaggctt ttaaattact aatttagtct tcttctattt cttctttttt
    32641 agatttaaca gttcctatag cccatttttc aaatggaact ttagttctat ttggtcctaa
    32701 ttctaatatt acaacatcat cttcaacttt agctacatta gctactattc cacctattgt
    32761 aatgaccttg tctcctacac ttaggctact tctcatttct tttaattgtt tgtctttttt
    32821 cttttgaggt ctaatcatta ggaaataaaa gattgcgatt actactaccc atagacctat
    32881 actcataatt atttgttgct gtggcattaa tttttcactc ctttgtaaat tatactcttt
    32941 tgtaaatcat aataaatgtt tatataacaa tttactttct ctatctttga gtactattga
    33001 atattatata ttaaaatgat tataattaat agtgcaaaac ctatatttca tatccatatt
    33061 ttgcaaaaaa ttcatttcta aaatcaagta atctatcttc cattatcgct tgtcttattt
    33121 gtttcattaa atttaataaa aagtgaagat tatgagtagt tattaatctt gcacccagta
    33181 tttcatttgc ttttataagg tgtcttatat aagctcttga atagttttta caagcataac
    33241 aatcacattc agggtcaagt ggagtaaagt cttcagcata agttgcattt ctaactacta
    33301 ctttaccttg gctagtcatt gcagttccat ttctagcgat acgagtaggt aggacacaat
    33361 caaacatgtc tactcctctt ataacacctt ctactaagtc atctggacta ccaactccca
    33421 ttaggtatct tggtttatcc tttggcataa gtggagttgt atgctctaac acgtcataca
    33481 taagtggttt tggttctcca acactaagtc caccaatagc atatcctggt aaatcaatat
    33541 tagttatttc tttcgctgat tgttccctta agtctttata catcccacct tgtattatac
    33601 caaataaagc ttgcttgtcg gtattattat gggcatcttt acatcttttt aaccatcttg
    33661 ttgttctttc taaagaattt tttacatatt ctctatctga tgggtatggt gcacactcat
    33721 caaatgccat cattatgtct gaacccaatg cattttgtat ttccatagct ttttctggag
    33781 ttagaaaatg ttttgaacca tctaagtgtg acctaaattc tacaccttct tcttttatct
    33841 ttcttaaagg ccctagacta aatacctgga accctccact atctgtaagt attggtttat
    33901 cccaattcat aaacttatga agaccaccag ctctttttat aagttcatga cctggtctca
    33961 tatataaatg gtatgtgtta ctaagtatta tttgtgaacc aatctctttt aattcttctg
    34021 gtgtcataga ttttacagtt gcttgagttc caactggcat gaatattggt gtttcaataa
    34081 tcccatgtgg agtgtgtaat cttcctaacc ttgcaccact ctgcttacaa gtctttatca
    34141 attcgtatct tactgcgtac ataaagttct ccttaatcat atttatttct cattatttct
    34201 taagatatat ttgtaataag ctattcatat aatttattgt ctaaatagat ttatcttcgt
    34261 cttctttgtt ctgttgttcc ttaattgctt cttcatcatg aatactcatt atattaagag
    34321 cactcttgtc ttttgttact aaaaactttt ttatagcaaa tagtcctgct atagctataa
    34381 ctcctattaa aacatctatc ataccttcat ttttaggcag tagcaacatt tttctagcaa
    34441 ttgcgtaaag taatgcctca ataaatgctc ctggtatatg aagagatagc attactacaa
    34501 gttcaacacc tattactaaa agtaatattt gtgctaaaaa atcattaagc tgactgtatt
    34561 gtactggatt ttgaaaatca actatatatg ctccccacat aagtcttaga acatctatag
    34621 ttcctaaaaa tactgctatt agaactacta ctgctaaaac acgttcaaat ataaaagcaa
    34681 tctttaatat agggttattc tttttttgtt tttgtaaact atgcatctat tacctcccta
    34741 ctttataatc atagcatctc caaaactgaa gaatctatat ctttctttta ctgcctcatt
    34801 atatgcattt aaaacattat cctttccaca aatagcactt actaacatta ttagtgtaga
    34861 ctctggtaag tgaaaattag taataagttt atctaaaact ttaaatttat aacctggata
    34921 tataaatatt tctgtccatc cactagtttc tttcatcttt ccatcctcat tacaagctga
    34981 ttctatagtt ctacaactag tagtaccaac acatattaca ttttttccat tttcctttgc
    35041 tctatttatt ttgtcagctg cttcttggct aaccatataa tattctgaat gcatcttgtg
    35101 atttaaaaca tcctctactt ttactggtct aaaagttcct aagccaacat gtagagttac
    35161 aaaggctata tctacacctt tttcttttat tttatttaac aattcttctg taaaatgtaa
    35221 tcctgctgta ggtgctgctg ctgaaccatt atgctttgaa taaacagtct ggtatctttc
    35281 tttttcatct agtctagcag tgatatatgg aggtagtggc atatttccaa gttcatccaa
    35341 tatttcttca aaaattccat cataatggaa ttttataatt cttgaacctt catctgataa
    35401 atctacaact tctccaatta gctttccatt tccaaaagaa aatttagtcc ctacttttgc
    35461 tctttttcct ggttttacta aagcctgcca agtatcttcc tctgttcttt ttaataataa
    35521 aaactctatt ttacctccag tttcaagctt ctctcctatt aatctagctg gtataactct
    35581 agtattattt aatactaagc aatctcctgg atttaaatat tctattatat ctctaaatac
    35641 tttatgttca atattacctg tctctttatc taataccatc aatcttgagc tagctctatc
    35701 ttctatagga acttgagcta taagttcctg tggtaagtca aatttaaaat cacttgtttt
    35761 caatgttaaa cttcctctct taaaatttct ccagctacaa taatatcaaa aaaacaactt
    35821 attttccaca atattaccat aatctatcaa gaaattgcta tttttaacag acaccatatc
    35881 cacaatatat agatattttt ccacgatata catgccttat ccacaatata tagatacaat
    35941 acacacaatt tttatcgtgt ttatccacag tatctacaga tataattacc attttgtgga
    36001 tatgtttgaa tttttagcca ttttagaaat attttaattt aatgactctt ttattttata
    36061 aatactcgta taatctattt ttatttttca ttgggatatg gaatttttaa gtgttcatat
    36121 gctaatggca tagctactct tcctctagga cctctattta taaatcctaa ttgaagcaaa
    36181 tatggctcat atacatcttc tattgtattt ctatcttctc cgatagaagc tgccaatgta
    36241 tctaaaccca ctggtcctcc tctaaatttt tctattatag tcataagaag cttctcatct
    36301 acaaaatcga gacccaaact atcgactcct aaaagttcca gagcatcttt tgccacttta
    36361 tcagttattt ttccatcagc tctgacttgt gcaaaatctc taactctttt tagtaatcta
    36421 tttgctatcc ttggagtccc tcttgaacgt tttgcaagtt ctaatgctcc attagactgt
    36481 atctctgcat ctaagatgct tgaagaccta agtactattt ttgaaagttc atcaactgta
    36541 taatagtcca atttacaaat aacaccaaat ctatctctaa gtggatttgt aagcatacca
    36601 gctcttgtag tagctccaat aagtgtaaat ttaggaaggt caagtcttat gcttctagca
    36661 gatggccctt tccctattat tatatctagg caaaaatcct ccattgctgg atataaaact
    36721 tcttcaacac ttctattgat tctatgaatc tcatctataa ataaaacatc attttcattt
    36781 aaattcgtaa gtatggctgc caaatctcca gctctttcta ttgcaggtcc tgacgtaatt
    36841 cttaaattta cccccatctc attggctatt atacttgcta gtgtagtttt tccaagacct
    36901 ggtggtccat ataaaagcac atggtctaac tgctcatttc tcgatttagc tgcttctata
    36961 aatatactaa gttgttcttt ggatttttct tgacccaaat aatcttctaa agtttttggt
    37021 cttaaactgt tttctatatc tatatcttcc atcttcattg tagaagttat tatcctattt
    37081 tcatcttcaa aaccttgcat ttatacccct cctctcgtac ttttgaaaat ctactttata
    37141 tattttcaaa tttacataaa ctccttaaat attgttttaa aatccaaata ttataaaatc
    37201 caaatactat ttcaaggatt tactcattat atatgtaagt gctttcttta taatagcttc
    37261 tgtattcata ccatcttttt tacatttttg aactgcctct tttgattccg acaaagtata
    37321 gcctaaagct acaagtgcat ctacagactc atcttgtgat atcaaggtag gtttttgtga
    37381 taataacgtt ggttcaaact ctatgttatt tttgtctacc ttatccttaa gctctaagac
    37441 gattctttct gctgtctttt taccaacacc aggagctttg gataattttc caatgtcttc
    37501 acttaaaata tatgctccta actgtgctgg tgatgcaaat gatagtattg aaagcgccac
    37561 cttaggtcct attttagata cagatgttag taattcaaac atcttaagtt cttccctact
    37621 tacaaaacca caaagactca tatcatcttc tcttacaatt aatttagtat atatttttgt
    37681 ggcttctccc acttgtaaat tcattattgt attggatgat acatttattt tatatcctat
    37741 cccattattt tcaacaacta tactgtctat ataaatttct tctactgtac cttttatata
    37801 actatacata cttaccacct atattcttta gagttttttc aagtttgttt gaatgagcat
    37861 ggcaaatagc cacagctaaa gcatctgcaa catcatctgg ttttggaact ttttttagac
    37921 ttaaaaatga agttaccatc tgttgaactt gtgccttatc tgctctccca tatccaacta
    37981 caccttgttt tacttgaagt ggagtgtatt catatacagg cttcccatta tgagcacatg
    38041 caagcatagt aacacctcta gcttgtgcaa ctgttatagc tgtttttaca ttcttgttaa
    38101 agaataattc ttccattcca acttcatcta tattgtaatt ctttactatt gtatcaattc
    38161 ctttatacac aagttccaat cttctcgata tattcatatg ggcaggtgtt gtaactgctc
    38221 cataatcgat tgctttaaac ttgctatttt tgtattcaat tataccatat ccaactatgg
    38281 ctatacctgg gtcaatcccc aatattatca ttttttaaaa ttccccctaa aaataaaaga
    38341 aataccaaaa tgtatttctc ataaaaactt atgttctaaa tcattatatc ataaataata
    38401 ttaacaaatc ataaaatgct ctatgtaaaa tataaaatca aataaaaaag ttatatcaaa
    38461 gcaagatttt acctcaatat aacttttata tttattacaa ataaattatt gtatttttat
    38521 aggaattaaa tgtgactaca attttaatac taatctattt aatattaaat tatttattat
    38581 taatttactt agtatttaac ttaaaataat attaatttac tattaacttg caaagtcttc
    38641 taatcttgaa taggcctctt cttcagtatc cataactaca ccttttttga tttcatcttg
    38701 aactgtttta ggaagtgaat ctactcttat ttttgttttt tctactaatg ttttacttcc
    38761 gctatcatca tatttatata gtgctatatt tccattatca ttttcaatag tatatttacc
    38821 ttttatagta acatccattg cttgtacatc tttattatca ctatatttag attctaccaa
    38881 tatgatttca tttttatcca tactctttat ttttttagtt ggatattctt ttttaaaata
    38941 tgatactatt tctgacttcg tcttatctaa taatgactct ggaactattc ctgccattgt
    39001 aagtgttctc ttatagttag tttcattttc gccttcactt tgaagccaaa cttcacaatt
    39061 tttatttaat ccaaaagctt cttttgactt ttcattcata ttcgcactag tacttacaac
    39121 ttcaccagtt tgaactccat tgtgttttaa tcttgtccct atataaactc cgctacttaa
    39181 tacaaatact ccaaccagta ttaaggcaga tattttccaa ggaaataatt cttttttctt
    39241 cttttcaaac attgattacg cctccttttt ctattatttt ctccaagctg taagttttta
    39301 tacaatttag gtaaatttta gaagaaaata tatttatatt tcaaattact ctaagaatag
    39361 atattttcta aaaggtagtt ttctcttaat ggttatattc ttgtaattat atggacataa
    39421 tttataataa ataatcgttt aggaggtaat aactttggaa agaataaact gtaatgtaat
    39481 taactgttca cataacaaca gccatatatg ttatgcagat aaaattttta taaatggtga
    39541 aaaagctcac aatgacagac atacttgttg tagttcattt ttagatgaat ctatttatag
    39601 taatttatct agcaacgtta ataataaaaa ttgtgaggaa ttagtttgta ctgtaaaaaa
    39661 ttgtaaatac aacaaagatg gtagcttatg tacacttgat aatatattgg ttgctcctga
    39721 aactgataga gtaaaccttt atattgaaac atgttgctct agtttcgaat gtaaatagtc
    39781 atagtataaa tataagggtg tcaaatgtaa ttaaactaac atagtgtaga gtatctacaa
    39841 ctattagttt gattatactt gacaccctta tttattttaa ataaaatttc attattataa
    39901 ccatgtttat aatgttctaa ctgtaattaa atttgataaa tttctataaa ttggtataat
    39961 caatatgtaa attgaattta gtaaattaat cataaaaata aaatatcgag tatatagtgt
    40021 tatactaact agaaatgagg tgcttatgag tacattttat attcaatttc tttattttgt
    40081 aatttatagc tttataggat ggtgttgtga aactacatat tgttcagttt tacaaaaaca
    40141 atttgtaaat agaggttttt taaatggtcc attttgccct atatatggat ttggagcatt
    40201 agcaatagtt gctaccttga ctccttttgt acacaatatt cctttgttat ttttgtttag
    40261 tataattata actagcataa tggagtactg tacgagcttt attttagaaa aaatatttaa
    40321 tatgacttgg tgggattatt ctaaacataa atttaatatt catggaagag tttgtctgga
    40381 aaactcactt atgtttggtg tattatcatt gattgtaatg cttatagtac atcctattgt
    40441 ggttgacttt attaactcta tctctaaaaa tgtgctattt atatttgcta tatctataga
    40501 aatttatttt gttttagatt tagttatcac agtccataca attttacaat taaatggtaa
    40561 gttaaaacaa atcaatctta taattaagga attaaaagat aagaaagaat actacaaact
    40621 tattacacaa gaaactatag aaaacaaact tgaatcttta gttgaaaata gactggatac
    40681 tttggaagat aggtttgaaa tacttaaaga aaaagaaaat tatcgctatg ctaaaaatcg
    40741 tattgatgag ctaaaaaata aacttaatac tttgctgtct aaccacaaat tacttcatag
    40801 acgtataatc aaagcattcc ccaacataag ctctaataag catacagata ttttaaataa
    40861 aatcaaagaa aatattaaat caattaaaaa agataaataa taaaataaac acataagtta
    40921 aataataaaa atactaatac ataagattaa ggtttagaat attttttgta aaatactcta
    40981 aaccctaatt aatatactat tatttttaat cttaatttat aattttagtt tattttaatt
    41041 ttaactcagt aaatttaagc gtttaaactt caatacacta atatactacc ccatcaatat
    41101 ctcaactgat tctctaagtg tgctaatctc tcccacattt ccagggaaaa ttatatatgg
    41161 catattagga aatttgcttt ctttgcctgt catccatact ggtataccag gttttatctg
    41221 tcccattact gtagcttttt ttactcttag tgctttagta ccaacatcac tagaagtaat
    41281 tccaccctta gctataataa aatttggtct tacattaagc ataccaatta tactggtaac
    41341 tgcatctgat atttctacag aaatcataag ctgtttatct ttatcattcg tatccaagtc
    41401 aaaacgctct cgtctagtat aaacagcaac agttttacca ctgcttattt tttcctctac
    41461 aacttttata actcttttta cctcattttt tagaccattt tcttgaagaa ctaaatgttg
    41521 attaaattct ataaattcta tcggatattt acaattttta agttcttcta actgttgggt
    41581 agtcttattc acatgtgaac caacaagtat aattcctcca ttggtattac cttttgatac
    41641 taattcatcc ttagtaagta gttccttgtc actcactccg ccaagtactt ttgttatggc
    41701 agcagcgctt ctaaacataa attccttacc accatttact gctcgtataa acgcaattgt
    41761 aaataccttt acatctacat aatcggttgc atttacaata attttattga atccttcagc
    41821 ttttttaagt ttttctgtta tagcttcaat atttagctct ctaagttctt ttgacgaaat
    41881 atatatcata tcactagatt tgtactttcc atttgtcttt tcttcacacc actcacctat
    41941 atcagatgat ttatatccaa aagatttatc ttttgcaaat tcagtcattc ctgctggtac
    42001 aagtatttct ccttctttaa cataatgtac attatctata gtaaacctac caccttcttt
    42061 aaaaaatggc attattattt caccctgaaa taacttcccc gataatctct ctacttcgct
    42121 ttttaataaa ttagtttcaa gaggataatg tcctctcata gtagaatcac tacgacttat
    42181 gattataaaa tccttattaa ctttctttga tacatccaca atattctttg aaatttcttt
    42241 atgtgctttt gtagtttgag caacagtaaa tccccttgaa ttggtaagta taaaaaacat
    42301 actatttttc tcattaaagc cttgttccat actatcctta tcccaatcag tataaacaga
    42361 aatatcatga actgtttgta cacctgttgg gtcatcatct aatacaacaa tttttctatc
    42421 taaatgctta agctcatctg caagaagttt atttaatcta tcctcatcta cttgtttaaa
    42481 agtattaagt atatctatgc taattggttt tacttctctc atttaaaacg cccctttatg
    42541 taatttgtat agtctaaata taatttatat gatataaaca atagtttgtt atttatagac
    42601 ctggaagtgg tataattcca tttataacac taagcaataa aaccattata aatgctacaa
    42661 ctccagcaat ggttcctcca attgtccaag agtttaaagt atctttaact gataatccac
    42721 taaatcttga aagtacccag aatccagaat catttggaag ggagaaacca actcctccag
    42781 cacatatagc aagccctact aaaactggtg acattccagt tgccaaaatt gtaggtccta
    42841 aaattgatga tgttgttact aaggctacag tagcagaacc ttgagaaatt ctaagcaagg
    42901 cacttaataa gaatccaagt actacaactg atatactaag accagacata gtatcaacta
    42961 agaagttacc tataccactt gcatttataa cactgccaaa cgcaccacct gaccctgtta
    43021 tcaataatat tagccctgct gaatcagcag cttcaataac tacatctccc ataggtttat
    43081 ttatgtattt ctttaaaaat cctattgcca ccaatattcc aagaagtatt gctatgtttt
    43141 tatctcctat aaatgcaagt actccactca ttgtagaacc tttttctaag aacatactaa
    43201 atacatttga tataagtata agaagtattg ggaacaataa agaaaacata gaaattccaa
    43261 aacctggtac tttagaagaa tcatcatctt caatttttat gctatctttt ccctgctcta
    43321 aatttttttc tctatcattc tcatcaatag cataagctgg atatttttca aaacgttttc
    43381 cataaatcca tccacctata agagctgctg gaaaagcaac aattatagaa taaagtataa
    43441 aactacctac atttgcattt acatttgctg caactgccaa aggtcctggt gtaggtatta
    43501 caagtgcatg acctactata gtcccaactc ctaaggcaca tacaaaaacc attagagatt
    43561 tcttagttac tctcgaaaca tacttaatta taggcatcat tataacaaaa gctgcatcca
    43621 taaaaactgg aattgaaatt aaaaaacctg ctgtagttac tgctaaagca ctgttttttt
    43681 ctccagtctt agctaacaac ccctttgcaa tagattctgt tgctcttgat tctgaaagaa
    43741 tatttccaaa tattattcca agtccaatta caatacctat actacctaat gtatttccaa
    43801 atccagtcga tattgtggtt gatatttcat ttataggcat tctaaccata aagcctgtaa
    43861 ttatagatgt tatcagtaat gccaaaaacg gatttacttt aaatttaata atcgatacaa
    43921 gtaaaattcc tatagatata acaaatgcta tcaaaagtcc atatcctgta atcataatct
    43981 ttaccccttt atcattctac tttattattt atcaatttta tttttctttt actatgataa
    44041 cttaacctcg ctgtatttat ataatctaat cctaataata tgtatttaat tatattgata
    44101 tatttaaata ttaattatcg tgttttttta tttcaacacc tgccaacttt tcaaaatact
    44161 gtgctattcc actatggtca tcttccaaat gtccatgtac ttttaatgtc tgcataattt
    44221 ctaataattg acttgtcata ggtagtggta catctaaatt gtgtgctgtt tgcattacat
    44281 tcttaatatc tttcaaatta atagatattt ttccacctgg tttaaaatca cgattcataa
    44341 tcattggtat cttcacatcc aatattgtac taccagctag gcctcctctt attgccttat
    44401 atactttttc tgggtctgca cctgcttttg ctgcaagtac aaatgcctca gaaactgctg
    44461 ctatcgtcaa attaactatt acttggtttg taagttttgt aacacttcca ctaccattat
    44521 ctccaattaa aatagatgag cttcccatta tattaaaaaa tggctctact ttcttataaa
    44581 tttcttcctt accaccagcc ataaaagcaa gtgtaccatc aatcgctttt ggctcccctc
    44641 cacttactgg tgagtctata aattctaagc ccatatcttt taatttattt gcacacaata
    44701 ttgattctgt aggagtaact gaactcatat cgactactat acttccttct tttaaagttt
    44761 ttgccaatcc atccatccca aacaatatat cctgcacaat agttccattt ggaaggattg
    44821 taaatacaat atcacattct tgacccattt ctaaaacact tgcgtatttt gctccacatg
    44881 atataagttc atccacagca gatttattaa tgtcatacac caaaagatta catccatctt
    44941 ttaataaatt ttttgccatt ggctttccca ttatccctaa tccaataaat cccaatttca
    45001 ttttataacc ctccatatct tcacattttt gaaaacgttt tttatgtttt agagtatact
    45061 acataccagt ataccggtca atataaaata taaaagtatt tattttaaca ataaatagta
    45121 atttttaaag tcatttatta tatttagtca tcctatataa gttttaatac atactattgt
    45181 tttcaaatat aatatactac ttttacagtt ttgtatttta actaatttca attagtttta
    45241 attaatctgc ctttaatgtt aatcatgctt cacacttcaa taatttttta tattttttaa
    45301 tcttatctgc aatttaaatt gcaaaagatt gaccttattt tcactatgtt gtatgcttaa
    45361 aattatataa gtttttgtat ttttatattg tttagggggg tattattaag tatggctaca
    45421 tttaaaagat tacaagaaca agcatatgac tacttaaaag aattgatact atctggagaa
    45481 atgatagaaa atgaaatata ttctgaaaca aaacttgcta gtgaaatagg tatctctaga
    45541 acacctataa gagatgctct tcaaagactt agtcaagatg gatttataga tataatccca
    45601 agcaaaggat ttagaatcca tcaaattaca gcaaatgaaa ttgtagagat attccaaata
    45661 cgctctgcaa tagaaggatt ttgtactttt ttaattacaa gtcaatacaa agaagctaga
    45721 gcagtagaaa ctataagtaa attaaaacat cttttagata aacaaaaaga tattttatta
    45781 ggtgataaaa atttaaactc atttgcagaa tacgatacat tatttcacac aactatagtt
    45841 tcatatgctc aaaatactga atttgacaaa atgtttaaca attatatgta cagaataaaa
    45901 aaattagctc tcgattcatt gtcacatgaa ggaaggcttg aaacaacatt aaaagagcac
    45961 acagatattt ttaataatat tgcaaatgga tgtattgaag atatttacag aactactctc
    46021 attcatatgg aaactcctaa atacattaat ttagaagatt tttgtaacaa taagttattt
    46081 tagtattata ctttcattta ttaaaaatat atctatctca aattaatttc ctaatttata
    46141 aaaaatattc tataattata ttgtaactaa tacttattct aaggagtgat ttttttgaac
    46201 gaagatgttg taactaatga aactattgac aaagattatg ctattgaaga agttcgtatg
    46261 gcatgcaaac attttggtga tttatatttt tatttttcca aagtgttatt tgaagagttt
    46321 ggtgaagata aaactagcga aatattaaga aaagttttat ttgaaaggtc tgaagaaaga
    46381 gctattgcta tgagagagag agctcatgaa aatggagatg aattaatcgc agacaatatt
    46441 attagcacaa ctgatgttcc atttctagga tgggttcctg aatttgaaga gttacattgc
    46501 ccctatggag cttcttggct tttaagattt gaggaaaatc cttggtttaa aaaatttgct
    46561 tctctttact gtgatgttac agatactact gtagctgaag tatttacagg agatacgtcc
    46621 cataaaataa caaaaaacat tctatgggga gataaaagtt gtgaaagaat atatttccat
    46681 gatgacaagg tatctgaagg taaatatact tatggaaata aaaactgtaa ataaatgatt
    46741 taaattttct atattcatat actatatttt gtactttttc atataaatat tataactagt
    46801 cttttatttt acttttgttt aacctaaaga taatttactt ttaatctata tgaattatca
    46861 tataaataat cagaaagtta tctttataaa ttatagtttt agatttataa tttataaaat
    46921 atttatgttc tttgtaaaat tttttagaag cttctaatgt tatgctataa aactatcttg
    46981 agaagggctg attgaatgtt taataaaata tatgaaaaga aagaatttat agtttttcaa
    47041 gttaaaaaag gttatgtagt ttataatact agaaagagtt ttgaagaagg tcatacacat
    47101 ttaaagcatt ttgaagcagc aaagacagct attgatttag caataaataa aaagattcct
    47161 agaagcaaag atggatatta tctgactagt ttaattcgca taagtgatga tggttattac
    47221 attgataagt taagcgaatt gttatatgtt agagaacaaa aaggtaaaaa agaaaagtac
    47281 tgtaattctg gttatcagat gtaacaagac tagttgtgaa ttataagtac caatcataag
    47341 tacctttagt cttaaaatca aagagtatca gtaaatctat aaaaaaacaa cttactgata
    47401 ctctttttaa ttatatgatt aatatttgaa tttgatacaa aattttatac aaaagtttat
    47461 gttatctatt ctgattcttt gtctgcaaat tggctattat aaagcttctc ataaaatcca
    47521 cccttttcca ttaattcatc atgattcccc tgctctataa tacttccatt attcataact
    47581 aaaatcaagt cagcattgcg aattgtagaa agtctatgtg ctataacaaa actagttcta
    47641 ccattcataa gatttctcat tgctttttga agcataagtt ccagcctagt atcaacagaa
    47701 ctcgtagctt catcaagtat caatattgaa gggtctgata taaaagctct agctatggtt
    47761 aaaagctgtt tttcccctag agatatatta gatgcttctt catttaaaaa catattgtat
    47821 ccatctggaa gagtggttat aaagtgatga acatttgcta cttttgctgc ttgtataatt
    47881 tcttctttag tagccccaaa tctaccatat tctatatttt caaaaatggt tccattaaat
    47941 aaccatgtat cttgaagcac cataccaaac attgaacgca aatctttacg tttcatatct
    48001 cttatatcta ctccatcaat tttaatagca cctttcttta catcataaaa cctcatcaat
    48061 aagtttatta atgttgtttt acctgctcca gtaggtccaa caatagctac catctgacca
    48121 ctttttactt ctgcatttaa atcttctatt aaagttgaat tttctccata tccaaaatta
    48181 acatgctcaa atgtaacatt tccttttaca ttttctatct taactggatt ttcaacatca
    48241 ggtatttcct cttcttcgtc taaaatttca aatacacgtt ctatagctgc aaaagaagat
    48301 tgtattactg tagataactg agtcatttgt gaaagtggct gatttatctg ccatatataa
    48361 cgcacaaatg cttgtaaatt tcctactgtt attcctccac ttactgcata tatagaaccg
    48421 acaactgcca cagctgcaat tccaaagtaa gttactaatg aaaccatagg attcatcata
    48481 cttgatataa attgtgcctt aaatccattt tcacaaagtt cttgatttac ttttttaaat
    48541 tcttttatag aatcttcttc tttaccatat agttttattt cattaaatcc agtatacatt
    48601 tcttgtactt ttccatttaa ttttccaaga gcattttgtt gcaatgaaaa tctactttga
    48661 gattttttta ctacaaattt agatacaaaa taactaattg gaattataaa aagagctata
    48721 agagccatat atatattaat tgtaaacatc attgaaagtg ccaaaattat gactaagatt
    48781 gagtttacaa tttgcataaa actctgctgc aatgcatttg atattgtatc tacatcattt
    48841 gatatacgac ttaatacatc tccaaaacta ttactatcaa aataactaat aggcaatctt
    48901 cttattttat tttcgacttc atttcttaaa tctctcattg tgttttgaat agcattcgta
    48961 agtagaaaac ttgaagtata cgtaaaaatt gcattggcaa aatatataca tgctaaaatc
    49021 accaatattt ttgttacata atcaaaattt acggaagccc ctggtactcc ttttgcgata
    49081 ctaattacat ctttagtcaa ttgtgttatt atcaatcctt cagttttagg tgcaagtgca
    49141 ttcatagtag ctgctgaaat tatacatata atagctataa taaaggaaaa tttatatttc
    49201 tttacaaatg gaagaagtct accaattgtt ttcttaaaac ctttagactt tttcattatt
    49261 ctaattcctc cttttttaac tgagatgttg caatttcata gtatatttca cagtttttta
    49321 ataattcttt atgagttccc attcctacaa cttgtccttc attgagtact ataatcttat
    49381 cagcatcaat aatagaacta attctctggg caacaatcaa tacaattgca tcttttgttt
    49441 ccttcttcaa tttagcacga agtattgcat cagttttaaa gtcaagtgca gaaaaactat
    49501 catcaaaaat gtatatttca ggtcttctta taatagccct tgcaatagaa agtctttgtt
    49561 tttgacctcc tgatacattt gctccacctt cactaatcaa ttcatcaaac tttctaggtt
    49621 tttttgatat aaactcatat gcttgtgcaa cttttgcgga atattctaat tctgactctc
    49681 ctgccttatg tttcccaaat ctaatattat ttgctatgct accagtaaaa agcagtgatt
    49741 tttgaggtat gaatcctatc ttttttctta aagcttttaa atcatattct cttatatcta
    49801 ctccatttat cttaatgcta ccttctgtta catcataaaa tctaggtatc aagttaatta
    49861 gagtactttt cccactacca gtacttccta taaaagcgac tgtttcacct gtttttgcag
    49921 taaatgaaat atccttaagt acagaagctt ctccatctgg ataggtaaaa gttacattat
    49981 caaattctat gataccctta ttttcagtat ccttaattcc attttcagga ttttttatca
    50041 atggttcttc atttaatagt tcttttattc tatttgcaga tacctctgct cttggataca
    50101 taataaatac cattgaaaaa agcataattg aaaacatggc atggaaaaga tattccaaaa
    50161 atgcaaccaa ctgtccaact tgaagctctc caatatttat cttctcactt gaaatccaaa
    50221 atacagccaa aacagctata tttaatagta aaaagaatgc tggttgagta attgacataa
    50281 gcttaaatag tttcttagaa acattagcat aatatgtatt tgttttttca aatcgctctg
    50341 tttcataatc atcatttcca aaagctctaa ttactcttat tccagttaaa ttttctctcg
    50401 atataaggtt taatttatct agtccttttt gttgttttga agatattgcc tgagatactt
    50461 ttgctattat tgctactcca ataattataa aaggtactga tatagccaat actatagaaa
    50521 gttccacact tgttctaatt gtcattatta tacttataat gaacataact ggagttaata
    50581 aggcagtcct tagtagtata ttaacaaatt gttgaatttg aaatgcatca ttcgttgttc
    50641 ttgtaatcat tgaagaaatt ccaaatttat tgtattcagt atgtgaaaat tcttgtgatt
    50701 tctcaaatat gtcatttctt atatctctgg ttacacttgt tgatacctta gcagaacaat
    50761 aacccaacaa tatactacct acaaccccta taatagaaat aataacaatc actattccca
    50821 tttgttttat gtaagctata ttctgatttg caataccatt gtcaattatt ttagctatta
    50881 tagttggaat ccccaactcg actaatgcaa aactaaatat agccagtatg tttaatacta
    50941 ttaataactt ataattcttt aaataactta aaattaattt catatttttc tcctttctta
    51001 atttttgaga tagtgtaatc atgtaataat actaaattta taaatgctta attttataaa
    51061 aaaaggagaa aagagttaac gcactctctt ctccagcata ttctttttaa tacaccctcc
    51121 gacaagtcgc ttatatgtta acatatttga caagtaatgt caattcatat agccaaaagt
    51181 cttttaaatg cttcgtttca taacattgta acaaattggc atgtaattta tttttgtttt
    51241 ttactgtatt ccaattttac aagttctcca atattactag ctttcttaaa attcaaatta
    51301 gtcttatcta taccagactt aaatagtgaa atccctctcc ccaatattat tgtcaatata
    51361 tatatataat aatcatcaat taagttatct ttcataaata attttactat atcgcctcca
    51421 ccaactatcc aaatatcttt tttatccttc tcttttccaa tttgctcaat taatttttta
    51481 ggttctaaat taatttatag tgtgattatt ctatgtaaac atcacttttt tactcattca
    51541 ataataccct attaataaat cctcaaacta atttaaataa actttgtata aaattaaaaa
    51601 tatattatat aaataattta aaactacact aacttattga aaattctaat tattacaaat
    51661 aaatattgct ctctgttaac gctagttcta taatataatt ataagctatt aatattataa
    51721 agccgatatt actaatataa taattataat acttatagtt aatttacttt tgttgaaagg
    51781 tggtaaataa catgaaaatt tcagaagtcg ctactccaaa ttttttgcta gatttagacc
    51841 agttagaaaa gaatatagat aaaattcaac aaatttgtac aaataataat aaacaacttt
    51901 ggcctatgct taagacacat aaaagtactt acatagcgag acttcaaaaa aatgcaggtg
    51961 ctagtggttt tctagttgga acacttgatg aaggtgaagc tctgataaaa gcaggttttg
    52021 aagatattat gttggcttat ccttacatgg gagaagtaaa tataaataga attgtgacta
    52081 tggcatcaaa aataaattta atctgtgcta cagataatat agaatgtgct aaggcttata
    52141 gtgaagcttt ttctaaatca aaaatagagt gcaagctact tattattgta gattgtggct
    52201 tacaccgttt tggggttgaa ccagaaaaag tggttgaact tgctactgaa atttctaagc
    52261 tagaaaacat caagattgtt ggtataagtt cgcatccagg tcaagtgtat ggttgtagtt
    52321 ctccagaagg tgttccagat gtttgtgttc aagaagattc ttctatggag aaagcataca
    52381 aagctctaac tgataatgga tttaatatag aaattgtcgc ttctggtagt actccaacag
    52441 ttgaatctga agctgcttct aaaactataa ctgctgtaag acctggaaac tatgtatact
    52501 atgatgctat acagataggt ttaggttgtg ctactgaaga tatgtgtgct cttactgttg
    52561 tgtgcactgt aatctcaaaa aatagcagtg gatactattt aattgattgt ggaagtaagt
    52621 gccttggact tgataaaggt gcacatggaa atagtagtat tgttggttat ggtagggtat
    52681 gtggacatcc agaacttact attgattcac tttcagaaga agttggaaaa attaaagtaa
    52741 atggtgaaac tgatataaaa attggtgata gaataagaat tatacctaat cattcttgtt
    52801 ccactgcaaa cttgacaagt aatttattag gttttagagg agatacaata gaaaaagtca
    52861 tagaagtaga tattcgtgaa aattcaaaac aaatcatcct ttaaaaacac atttattctg
    52921 atattaacat gaaagtatat ttttcttaaa attattgcta ataactaatg ttaatgttgg
    52981 ataaataaaa aacataaatt ctagaaatat aaatttaaaa gaagaggctg tctcaaaata
    53041 gagataagcc tctctttcat tgttgaaatt atgaaaatat acttgatttc atacaaaaag
    53101 agtatctcat gaactaaaaa gttcactttg agatactctc tttttttaat taatatacac
    53161 attaattact atcttagttt attactatat atcaattact actcattaat ccttgtatat
    53221 attaattctt atatatcatt tatagttagg ttataatttt atgttattta cattaatccc
    53281 ataacagtga gtaaaactct tactatcaac atccccacta ttgcatcaaa tataggaact
    53341 gccaacagta acattctata cttagtactg gcatttgcta caagcactat tctggcataa
    53401 tgaccaacta gagtacccat taacatacat ggcataatta atatggttgc ttgtggtgca
    53461 gtgattagac cttgtgcaaa taagtttgca gctgtagctg ctcctgctgc cttagcaaag
    53521 aatgctgcta tcaaaactac aacagattcc ccaggtagtc caaaaatacc cattactggt
    53581 ccaaaaatat ttcctaaaat atcaactaaa ccagttaatt gtaaaaactg cactattaca
    53641 taacccatta tcatggctgg taatatctgt tcaacaccta tgtaaaaacc tttttttgct
    53701 ccccccataa atatctcaac agcagttttc ttaggtttac tatttacaat tacatttcca
    53761 gtattttgtt gactcatact acacagcctc cttagcctta ttctttttat ttcttacacc
    53821 tatgattaat ctaactagat tagcaccaag tattttacag aatatctcta taagtattat
    53881 tggacctaat gccaataatg ctattggtaa aagtggagct tgagtattta ttgtgttcag
    53941 tataacagct gaaccagcat attgatatgc tacaaatata gttctttcat catctgttat
    54001 ttccccactt tcaaataatt ctttcgtcat tattgaggct acatctgaac tagtaaatga
    54061 agatacaaat gctattcctg ctattccagg tataccaagc agaggtctaa gcaatggatt
    54121 aaatatcttt gatgccgctt tcattcctcc catagattca actacatcta taagacctac
    54181 agcaaaacag acagttggaa tcaaagtcag agcaaataag aaaccatctt ttgctcccgt
    54241 tcctccttta cccataaagt ctacaccatc tgcaatagta ccaaatgaac ctgtcagatt
    54301 agcaaaatct aatgctttaa ggaagccttg actatcttta aacactcctg aaaataatac
    54361 tatcaataca aataaagata aatacccttt ccatgttacc ttattatctc cagctgttac
    54421 atccatataa aatccccctt tatacctcaa atttatctaa gtttaaaata actgtagaaa
    54481 ttaatttcac cctctcaaac atagaatcta ctactgcata ttctcttgat gtgtggttcc
    54541 attctcctct tacaccaaat gaacagattg taggaacgtt tgcaatagtt aaataacttg
    54601 catctgaact acctccaagt ctcttagcat ttaattctcc aaatccattt tcttttgaca
    54661 cttcatttac aaatgtatga aatctcataa catcttctgt agtttcaaat ggcatcattt
    54721 cacttataaa attaacttct gtagaagttc cttctatgta agtttcttta catatctctc
    54781 taacttgttc tttaacattc tccatttctt ctactttttc aaatctaagg tctactttta
    54841 tactacaatc ttctggaata gaattttcca ctcttccacc cttaatcaca cttacactta
    54901 ctgtagttcc aacatctaaa ttagtcaatt tttgtatgcg tagtatctta ttagccattt
    54961 cttctatagc atttcttcca ccttcaaaat cattacctgc gtgtgtttct acacctttta
    55021 catgtatatt acatcctatt cttccttttc tacctacaca caaactatta tctactaatc
    55081 cagtttccat attaaaagca caaagaccac cttttgcttc cctcaatata acatctgcac
    55141 ctgttgaatc cttatgtcct atctcttcat ctccagaaaa tactattttt attggtcttt
    55201 ctttgtatcc tattttattt aatgctttaa tagcatataa ggaaattatt ataccaccct
    55261 tcatatctaa aacacctggg ccatatgctt ttccttctat tattttaaat ggattctctc
    55321 caaatgtacc tgtttcaaag acagtatcca tgtgacctga aaaaattatt ggctttttat
    55381 ctatattgga accaagtgta cctatcaatg tactaccatt atctccaaca tctactaact
    55441 cgcaatctaa accttctttt tcaaactcaa actttaatct cttagccaat ttatttacgc
    55501 tttctttaca atgtgtatag ctttccatat taacaatctc tttccataat gaaactattt
    55561 cttctctatt ctcatcaaca aacttagaaa tttcatttaa atatgtattc ataatcttct
    55621 cctttatttt caaataaaat gtatttcttt cctaaaatct aagtttattt taggaaatct
    55681 taaaagacta gtccttaatt acaaaatagc acaattattc ttgacagtca acatattttt
    55741 cagtcttttt tatattttct gatttttctt tcaattttcc ttttgtaaaa taaattgacg
    55801 cgttttatct actattataa aatgaggtta taaattgatt gattagttac aatactctcg
    55861 aaattttaaa ggaggtttta tgaaatataa aattggtttt ttgacaacat cttattttat
    55921 gtcagataag tttaaacaag ctcttaaaga attaaatgat acttgtgaaa ttacatttat
    55981 tgagcttaaa ggggagaatc cttttaataa tttacctaat atatactatg agcaagtaga
    56041 taattttgat ggatttgtat gcagtggtat agttccatat agtgaactta taataaatat
    56101 aaaagacata aaagttccat taaatttttt aaagcttgat gaaaaagatt tttataaata
    56161 cttattcaaa ttattaaata gccaaaaaga tattgacttt acaaaatcat ttatggattt
    56221 tttaagagag gacaacaatt attatgatat atattcatta atagactcta ataaatgtcc
    56281 atatacaatt aaagatttta atatccctca acctgtatat gactttaaaa aattaaatga
    56341 taaattattg gaaatacatt tagacttatt gcgagataat aagattaacc tttcttttac
    56401 tagaaattac atcattagtt gtgaacttaa taaacttgga tatgattcta tttacatggt
    56461 tccatctaca gaatcaatcc tgaatacatt taaatctctg gtgaatgaaa taacattaca
    56521 aaacttagac aaaaataaat ctgcaacttg tatagttaca gtaaatagtt cagagtacat
    56581 aaatgaagat ttgatattta aaaatgatga gatacaaaat caaatatata acactatatt
    56641 aaattctcta tcaagacatg gattctatgg agttcaggtc aaaaaaaatg atatgaaaat
    56701 agagatacac actactaaag aaatgttaaa caatatgacc aataactata cagatttttt
    56761 tatttcagaa gatttaaaag aaattaaata tagcttaaat ataggttggg gcattggaaa
    56821 tacaaatatt catgcagagc aaaatgctcg tcaagctaat ggtaaatctg cttctttgaa
    56881 tggaaactgt acttttatag taaatgatac taatgataca ataggccctt tatattcaaa
    56941 taaaaattct aataatattg aagatagctc aatagccaat aaagttgctt cttttatacc
    57001 tctatctaat acaaatgtat ctaaaatcat gtgtatgatt aatgatagaa attcaaataa
    57061 tgtgtcagca gaaatattag cagactatat gaacataact cttagaagtg ctaatagaat
    57121 attgagtatc ttatataaag caggaattgc aactattgta aatacaaaac tcgataatca
    57181 aagaggaagg ccaaaaaaaa tatataaagt tgatttctta tcttttctaa ataagatgca
    57241 gaaattaaat tcttaatatt taatttttta ataaaagcaa tgtattttct ctaattttaa
    57301 agaatcaaaa tgtttaaatt ttattagaat atacaacttt ttactttaaa atacctaaac
    57361 cttttatcag tgaaataaac cataatatat cgtaacttat tagaaaaaca aaataatttc
    57421 atatacaaat aataaaatag ccactacaat ccataatttg cagtggctac tttttacact
    57481 atcacttatt acttattttt aaaaattaat tgtatttttt aaataattta tacacaccta
    57541 ttatcagtaa agcaataaat acaagtatat ctataaaaat aattattgta acatgtctga
    57601 caatattgta aataaaaaat atagagaata tttctataga caacgctaca aaacacataa
    57661 aattcgttaa ataatctgca atagtatcac tataaaaagc atgtatttgt aaccatctcc
    57721 atataaatgg acgtaaaagt attctgaata caacacaaat gacagggtag gcataaataa
    57781 attttttatc tacataatta gctacaccat tattccattg gataggaatt tgaggtggca
    57841 acttttgaaa tactgttatt gcaatttaaa cactacctct ctattctatt aatttataac
    57901 tataatatag tcttaaatat tttcactcta taaaattgta tatttagtat atcttaaaat
    57961 caaactaatt atcttttata agttttcata caataatatc tcctttcaat aatatatctt
    58021 tttttatatt taaaactatc ttattttcta taaaataatg tataaacaag gtttacagtc
    58081 aagtattttt attatttttt tgatttcata aaaaaagcat agcaaattat ttgctatact
    58141 tttttactaa attatttatt ctatatctta tatgaactta ttgtttaact actacacaat
    58201 actagcttta atcatcatat tttttgcaaa catactggct tcatatattt cttgttcatc
    58261 tggatgactt tgagattcct catggttatt taattgttgg cgaatatgtt cgttgtcagg
    58321 agaaagtttt aacatctctt tatattttgc tttcaatcct tctgctatct taccttgaca
    58381 tatgaatgaa cctagtattt cattatcttt tgggataatt gattctatct tttctattat
    58441 actagctcca taacttcctt ttttacttgc tcccattgtt ccaaatagtg ctatcttttt
    58501 attgtgaata ttttcaagca cttgttttga atttttatca caaattccct tgtccaccca
    58561 atagcctaag aatactatat cataattttc atagtcaata ccataatcaa ctaattcatt
    58621 tacatcttta atgtcttttt cttcttgaat ttcatcatat atagtataag caatcttttt
    58681 agtatttcca gttaaacttg aatataaaac taaacttttc atgatgtctc ctcctcttta
    58741 tctaaatatt tatctaaatc accaaaaata tattaacctt aacaaattat ttatttttat
    58801 aaggatattc taatctagta tacatccaaa ctgagagcgt gtttgtaaag catctgcaca
    58861 cttcttatta caataacagc actttttaat ctcatctact cttccatctt ttactttctg
    58921 taaccaatta ctatctgcta gtaattgtct tgacatagaa accatatcta ctctattatt
    58981 tgaaataata ctttctataa aatctgggct agacaatttt ccaaccccac atactggaag
    59041 atttgtgtgt ttctttactt catcagctaa atataaaaaa cagccttctt ctttaaagta
    59101 aggatgatta ttggttggta tagtatcttc taattttgaa tgatttgcaa gtgttacatg
    59161 aaaactgttt acacctaggg attcaaattt tttaacaaaa tactcaactt ccgaaagtaa
    59221 aactcctgca tttccataat gaggattttc ttgtcttatt gcaaatttat agtctattgg
    59281 aatgtcctta acttcatctc ggatactact aattatttcg cttgcaaatc tacttctatt
    59341 atcacacgtt ctaccatatt catcatttct attattaaat atacttgatg aaaaacttcc
    59401 tacaagccta tcaccatgaa tttgaatcat gtcaaaacct gctttttttg cattcaatgc
    59461 tgttacttta aataaattta taatattttt aatttcttct ttgggcatat ttgttatgta
    59521 atcttttact ccgtcattca ttattttttt tatctcatca tgtgaagtaa ttcccatatt
    59581 catagtatct ttaattaaat taacatcata atctgaacaa aatagttgtg ctgatacctt
    59641 tgcaccagaa ttgtgtattt catctacaat tttcttgtat ttcatgactc catcttcatc
    59701 cgataggctt atagctacct tatgaaaact aggtctaata gatacatctc ctagagtaat
    59761 cagagctact cctgacttag caatatcaga aaacttttta attttttctt ccaatttaag
    59821 acccatgctt gtaggtgcaa aagatactct attttttaat tccaaatttc caattttaat
    59881 tggttttaat aaattacaat acatcctatt cttcctccac agctgttttt atatccttta
    59941 ccacatgtaa attctttacc agttctttat attctgtatc cgagaactct ttttttatgt
    60001 gattatccca ctttgaaaat atgtttttta tatcccctaa tacttcctca cccttatctg
    60061 ttactctcaa ctgaaaagct ctactatcat tagggttttg gattttttct atgtatccat
    60121 cttgttctaa cctagatata gttcttgttg tatgagcttt atcaacttca aattctgtag
    60181 aaacatcatt caaagaacaa ttcctatttt tattaatata aattaaatag aaatatagac
    60241 cattcgtaag tttatatggt tttaaacatt tttcacaata aagtttaaag tttttttgca
    60301 agttacaaat aatatatgac aaactttcat actgtaaatt tttaaaatcc atcttaaatt
    60361 tcccttctat aattataata tgtttgacta tatcaactat attatattaa acaattaata
    60421 tagtcaagaa tattttattc tctaaatcta tgttttatta attctttaaa aaactattat
    60481 ataaaataat catgataaaa ttagaaattg gaatttttaa tatgtactgt acataaatat
    60541 attttatata aaagtttata ttttcaaaca agtaattttt cgaaaattgt ctaaattcag
    60601 taaaaatatg gtaatatata cataagcaat ataaatctat aaaaaggagt gttacatatg
    60661 atatctaata aaatgcaaac tttagttgca aatagttctg ttataagagc tatgtttgaa
    60721 gaaggaaaga aactttctga tatttatggt gaggaaaatg tttttgattt tagtatagga
    60781 aatccaagtg ttgaacctcc agagactatt aaagcagtta taaatgatat tttaaatgaa
    60841 gaatctccaa atttagttca tggatatatg aacaactcag gatatgagga tgtaagagat
    60901 gctattgctg aacacataaa taaaaaagat ggattaaatc ttacaagaga aaatttaatt
    60961 atgacttgtg gtgctgctgg tggtctaaat attattttaa aaactctttt aaatcctggt
    61021 gatgaagtta ttgcttttgc accgtatttt ggtgagtata aaaattatac agaaaactat
    61081 gatggaaaat taatagaagt tcctacaaat atagagactt ttgaaccaga tttagatgct
    61141 ctaaaaaatg ctattactcc aaaaacaaga gctttaataa taaacactcc aaataatcct
    61201 actggtgtca tatattctga agaattatta aaaaatcttg gagaattatt ggattcaaaa
    61261 caaaaagaat ttaatacaag catataccta atttctgatg agccatatag agaaataatt
    61321 tatgatggtg ccaaagttcc ttgtgtacta aaatactata gaaattcatt tataggatac
    61381 tcttatagta aatcattatc tctacctggt gaacgtatag gatatattgt tgctaatggg
    61441 caaatggatg attttgatga tgttatgtct tcattaaatg ttgcaaatag aatacttgga
    61501 tttgtaaatg ctccttctct ttttcaaagg gttattgcaa gaagtttaga tgcagaagtt
    61561 gatgtaaata tttataaaaa gaattttgac cttctatata atagtttaat cgatatggga
    61621 tattcttgtg ttaaacctaa tggtacattc tatttgttcc caaaagctcc aattgaagat
    61681 gataaaaaat tctgcaatga tgcaaaacaa tttaatttat tattagtacc aggttcttct
    61741 tttggttgtc caggtcattt tagagtatca tattgtgtat cttatgataa agttaaaagt
    61801 tctttaccag catttgaaaa attagccaaa ttatataatt taaaataact aaatcaaagt
    61861 aattcaaata attaactacc ttagtataga atacttacat tctatattaa ggtagtttat
    61921 aattttatgt actatatttt atacatacca tattattcca atatgcttga atattcttat
    61981 ctatagtact aatataaatt acaaggaggt gtttgacttg aaaaaaggtt atgtttatat
    62041 aatactgact accttatttt ttagttcaat ggaaattagt ctaaaaactg tcactaatga
    62101 ctttaatccc ttacaaataa ctttatcaag attttttgtt ggcggtttag tcttactacc
    62161 ttttgctgta aaaagattaa gagctcttag tctttctatt acaaaatcag acttaaaata
    62221 ctttgcattt ttaggtttta tgtgtgtagt agtaagtatg tcattgtatc aacttgctgt
    62281 tctaaacaca aaggcatctg tagttgctgt tttgttcagt tgtaatccag tctttgtaat
    62341 gcttttagct tacttaattt tgaaggaaaa aatatatagg cacaatgtaa tttcacttat
    62401 attagaagtt cttggaatta tagttataat aaatccattg catacaaaac taactcttag
    62461 tggaatattc ttaacattat cttctgctat tattttttca atgtatactg tatttggtaa
    62521 aagaaaaacc ttaaaatttg gtggaatagt tgtaacctgc tttagcttta tatttggtag
    62581 tttggaaatg ttgatattgg ttttactcac taaaattaat tttatcgcag atatattaaa
    62641 taaaaataag cttcatgtat ttgcaaatat ccctattttt agtggatata ccttacacaa
    62701 tatgcccatt atgatttatg tattcgtatt tgttacaggt gttggttatg cgctttactt
    62761 tatggcaatg gaagctacat ctactagtct tacatcttta gtattcttct ttaaaccagt
    62821 aatatctcca atactagcat tattaatact taaagaaatt atccctataa acatggttat
    62881 aggaatttta ttgatagtaa ttggttcaat aatttctatt atacctacga taattactca
    62941 aatgcataat aaacacgttg aagccttgta taaggagtag taattgataa tctatcatag
    63001 ttatacataa gacaaaattt attagattta aacgcaatat aaaagagatg ctattataat
    63061 agcatctctt tatttatatt tattttaaat ttattaaaac tctatttagc taaattttgc
    63121 aaaaagctat aagtttgtgg acaagctgat tttaacttac tatttgtatc ttgatttaaa
    63181 tagtaatatg caaatgattc tgcaaaaaat tcttctggat atacacctaa gtagtttaca
    63241 ttacctaaag aacgaccttc tttagcaaat atttgtttga attgtgctga tttagatata
    63301 tcatttaata ctatatggtc tattgcatgt gctgtttcat gtaattctaa atttattgca
    63361 tcatgccctt tacctttgtt actaaatcct attctaagag ctactgtact tccacctaaa
    63421 cctggaacat catcccaagt ttttccagta ccttcccatc ccttaggaac tacacctttt
    63481 aaataagcat attctttttc atctgttaac tttccactta ataattttat ttttaagtta
    63541 ttttgcttta atgcatttaa atactttcca tctatattag ctaatctatt taccatagca
    63601 ttagcttcgt ttttatcgta atttccagtt ggaaaaacta ctatttgact aagtgtgtct
    63661 ttattttgtt gtatagtagt actatctgca tgtgcactta ctggaactga acttattaag
    63721 aatattgata ttatagctat taataatttt ttacttggtc tcatattatt ccctcctttg
    63781 agttaggccg ggagtaataa atttcaaaat aaaaaagata cccaagagta tctttgtata
    63841 tacaaaaaga aatttttact cttttcggca actggctggc atggtttact aaactttagc
    63901 ccctatagct ttgcgtgact aggtttccct agttttgcct catttaattt tatatctata
    63961 ttatagctta tatcttttta attgtctata tccctttgga acttttttct aaaaagttat
    64021 tattttttta cataaatctt caaaaaaaaa tatcttctaa caatattttc attattaaat
    64081 attgttttag aagatatttt ttaatataac ttatattttt tataatgtta gggtctaatt
    64141 tgtattttta tttcttctta atacgataag tcctacaata gctcctataa ccaaaagtat
    64201 ttctccaata attgtagtac tatcccctgt ttttggtggt actggtggat ttaccaaagt
    64261 atcatcttta actttattat ttttttcttc tgacactgat ggctttacta cttctggtat
    64321 tggaataatc tgtttaacag gagtttctat catctcttct gatggtggta ctggcggatt
    64381 caatacctct ggtattggcg gatttattat atcttctgat ggtggtattg gtggatttat
    64441 aactatagta tcctctgtat cagatgaact tgatggtttc cttggtttat ctgtgcttgg
    64501 tggtactggt ggatttacta ttggttcatc tgtatttggt ggtgctggtg gatttactgg
    64561 tggattttct tgtcttatgt tttctatatt tccaatatcc actattctac caatatcttt
    64621 attaccaatt tcaaccttaa ttttatcctt cagtttttca tatccacttg gagccattat
    64681 ctccactaaa taatatgttc ctggtttttt tatactagat tgaattatac catcttcatc
    64741 actaactaaa tccttaacta ctatatttcc aaatgcatct tctaaattga acttagcacc
    64801 tgaaagtaca tttttatcta aagcatccac ttttttagct tcaaaagcat aaccttgctt
    64861 agtagtctct actcctggag gacttgaacc attaatctga gccacatttc gtatagtctc
    64921 cccaactttt acatttgtga agtctgcatc aaatgtaacc caactttgca caggttcccc
    64981 ttcttttatc tgtttaaatt cgtatttatt tactaatctt attgtatttt ttccatctcc
    65041 agcttctttt ttaagttcaa gattatcaga atattttata ttagatattt ctagagctga
    65101 gtttacttca tctaaaagat ttacttgtcc tgcatcataa accccataag ttgacatatt
    65161 gattttgtat ttaacaatct ggttatcact actatttaaa acttttttat caacttcttt
    65221 ttttgcgctt attaatccag aatttttctt aaagtttatc tcatcatttt tatcaatttc
    65281 actattattt gcatcaagaa cagctctatt tatatagcta tcttcaatac taattacctt
    65341 taatgtataa gctataaaaa actttgattc cacttcttct ttactgagat taattgtaaa
    65401 tccagttata actttatcta cttgcccact ttcatttctt ttttcttcta ctttatatga
    65461 aatattattg gcaatttttt ctttactcca aggagtccag ctcccattca ttggaatttc
    65521 tacaactcta aaatcatgcc cagcttctcc tgaagtagtt aatctcatgc cttctggtat
    65581 attatctgtt ataacaacat tacttattgg tgatttatca tcatttattg aaatctgata
    65641 gtttattact tgaccaactt gagtaatatt tgttgctcct gaatgtcctt tagtaagaag
    65701 ataatcatct cctctatcaa atatacttac agtagcatca tcttcttgta tcttcttacc
    65761 atcagattca atcctagcta cattcttata tttattacca tgttttgcat ttttgtcact
    65821 gattctagcc ttatacttaa cagtatacga tttatctata tttccaagat taactgaaat
    65881 agaattttta ctctgttcaa tattaaaatc actaacttct tttccatcac ttgttactac
    65941 acttacagaa ccatttatca atgtcaatcc ttcaggaagc tcatcataca aaataatatc
    66001 ttttaactct tcctgctttt catttacttg tatactgtaa tttatatctt tatttttaac
    66061 tggcataaat acagtagttg atttttttcc ttcaacaagc tttttaagtg ttcctttagc
    66121 atctggaaca tccgttttat ctccaggttt tatttctaca tctatatctc cacttccact
    66181 ttctattttt ccagtagttt caatatgtat ttttgcatta gtatcttcat caaccttttt
    66241 aacatatgct tccaaaccta ttttaccttg cattacactt tggccattag gtaattctct
    66301 aaatgtaagt gtatactctc cattactttc tgttttatca aagcattcac ttgtataatc
    66361 taaattaact ttattgaata catctggcac cttaaaagtt attgaatctc ctgcttgtat
    66421 tccttttgat gttggagtat aagttaaatt aaatgatatt tttttcattg attccgtttc
    66481 tattgtattg ttattaattt ttacaacaaa tccatagtct tcattttctt cattaagttc
    66541 ttcttctaaa actttcaata aattttcatt ttctaataga ttatcttcct ctggagtttt
    66601 ttctgtattt ttattgtcta gtggtttttc atcttctaaa gcttgttctg actttttatt
    66661 atctgttgac ttatcttctt ctggtatctg ctctggcttt ttattatcta ttggcttttc
    66721 tccttctgga gtttgctctg gctttttatt atctgttgac ttatcttctt ctggggtctg
    66781 ttctggtttt ttattatctg ttggtttttc ttcctctggg gtctgttctg gttttttatt
    66841 atctgttgcc ttatctttct ctggagtctg ttctggcttt ttattgtcgc tttccttctc
    66901 ctctccagtt gatgaattag ttgaaccact ttgaatctga ctattctctc ctaattccga
    66961 agcataagat acagttggat atattgtaga caccaccata cttaaaatca taattaaact
    67021 aattaataat gcctttctat ttcctttctt catgtaaatc tcaccccttt aggttaccta
    67081 taatttataa tctaatcttc cattaatatc gtatataaag taatttttac taaaaaatta
    67141 tacaaaaaaa gctatgaaaa taaataaatt tatattcata gccggttgca ccactgactc
    67201 agtatatcca taaggtgccc aataatagaa tatacttcaa catctctata atatttcata
    67261 aaaacaatta aaattgcttt atttatatta aaaatacaat tatatacttc tattatatta
    67321 tgcctctata ctattgtcta tcctttttac attttttacc ttatgatgag attaattaat
    67381 aattaaataa aatccttatc tacaacaatt acacaattat attcaggatt tatctcctta
    67441 actaattttg ttatatcttc ttttaagtca tcttctgaca tgtttttgga aaattcggaa
    67501 ggattaacta ctatatcaaa tattaaattc ttcttgcttc cttttccaac tattctaaaa
    67561 tcatgcatag attttacaag actatttttc ttaagtattt cttcaagttc ttttttggct
    67621 gacataactt ctttatcttc aagacatatt gggtccatgt gaattactag atatatatct
    67681 aatttttcag atatttctct ctctgcagta tctataattt catgtatttc cattatatct
    67741 atgttggatg gaatttctgc atgtatagat gcaatacatc taccaactcc atagttatga
    67801 ataattaaat catgtgtacc tattatatat ttataagata acaatagctc tataatagaa
    67861 tttaccattt cttcatccgg tgcttcccct aaaagaggat ttatagtatc ttttacaaga
    67921 gagaaaccag cataaagtat cactaatgat actacgatac caacatatcc atctatggga
    67981 aaattagtaa atctagctac aataaatgat ataactacac aacttgaagt aaatacatct
    68041 cctaaagcat caagtgaaac tgcttttaag gctgaagaat caattttatt tcccataaat
    68101 ttattaaaac gactcaacca gattttaatc attatagatg caattaaaag tataagtggt
    68161 attacttcaa attttacagg aattggattt actatccttt ctatagatga ctttacaaat
    68221 tgaagtccaa ccaacatcac cataaatgct actattaatg ctgataaata ctctattctt
    68281 ccatgaccaa aagggtgttc tttatcagct ggcttacttg ctaatttaaa acctatcata
    68341 gttattgctg aagatgccat atcagaaaga ttattaaatg catcagccat tatagctata
    68401 ctagatgtga gcattcctat gaataccttt atcacaaata aaagtaaatt ggataatata
    68461 cctactacac cagctacata accatactta tttctaacat ctgtattttg aacgttttcg
    68521 ctatctctga taaatgtttt gactaggatt ttggaaaaca tgaaacttac ctccctgccc
    68581 tttattttat taacaaattt tataatctat atctttattt atgataacat aatttatata
    68641 taaaattctt aaaaatcact ctacttcagt aaaatattat tctatatatc tatttagata
    68701 cgaattttat atttagtaaa gtttttatgg cttagtgtct gtttaataga ttctatataa
    68761 gtttttacaa agattattta ttatgataat atcatttttc ccaagtatta cttagaatat
    68821 gatttttttg ttttgtctgt acatatttta aatttatact atatttatct atattttata
    68881 accttatgat acactataac tataagattt taaatggaaa ggaatgaaat aaatcatgtt
    68941 ttttatcagt gatatttaca caaaatcacc tattaaattt gatactcctt tgcaaaaaga
    69001 ggcatataaa atattacaaa aattagatat tgactttgaa tgtgttgaca cagatgaagc
    69061 aattacaatg gaagattgtg ttcagattaa taaaaaatta aatatgaaaa tggtaatata
    69121 aaacaacatt aaacaaacaa aaaccgcaaa gttacaatat atagtacttt acggtttcat
    69181 aagaattaat ttttactatt aaagttcata gttctactat ttttcattgt tctaagaatt
    69241 agctttacaa attcatttga caataggata gtggatgcaa atagtattat ctttatccac
    69301 atatcaaagt ccaaagaaac agaattaaag aaactctgga acacttgtgt aaatattatt
    69361 tgaattatcc ctgtaactac tattatttgc aatgccagtt tatttttaaa gaaatttggt
    69421 attgtactat ttaaaccaaa ctctctacaa tttaatgcat taaaaagggc actgaatgca
    69481 aataaagaaa atataacagt accttgttct tctgatgtag ctcccaatat attaaaagct
    69541 gattgagtaa atacaattgt aattataaga attgcattta taataatatt tacaaacata
    69601 gacctagcta ttattccaga atgtctattt attggttttc ttttcaatac ataatctcta
    69661 acaggttcta atcctaatgc tagggctgga ggaccatcca ttattatatt tacccataat
    69721 aattgtattg tagtaaatgg catatcctta ccagtaagtt gagatattat agcaattata
    69781 aatgctacta tatttacagt aagctgaaac tgtataaatc tttgaaagtt ctcatatata
    69841 cctcttcccc attttattcc ctctactata gtactaaagc tatcatcagt caatattata
    69901 tctgctgcat ttttagatac ttctgttcct gaaataccca ttgcaattcc aacatctgct
    69961 tgactaagtg ctggggcatc atttatacca tcacctgtta cagctacaac ttcgccactt
    70021 ttttgaagtg ctgaaactat tctcattttt gtatctggtt tacttcttgc aacaatagat
    70081 attcctttga tttcttctct caattcttta tctgtcaata catctatata tgttgcttca
    70141 actgcctttt tcccatcatt taataatcct aattcatttc caatagctgt tgctgtattt
    70201 atattatctc ctgtaagcat ttttacatct actcctgcat taaatgcttt atcaatggaa
    70261 tctttgaccc cttctctcaa tgggtccact attcctacaa atccactaaa aactaaatta
    70321 tcttccttca tataacttct tgaatttcct attaaattca attcaccttc tgaagtcatt
    70381 gcaacttctg ttttagaatt actcattttt ttataagcaa atcctaatgt tctcatagat
    70441 ttaatttgta acttcttaat ctcatctaaa atactttttt ctacttttgg agttattgga
    70501 acaatatttt ttccttgttg tacataagaa cattttttta ataatacttc tggagcacct
    70561 tttgaaagta atatatctga atcctcttga cgaattaatg ttgacatctt cttttcttct
    70621 gaactaaatg gtatttgtga tatcaaatac gtttgttttc tcatttcatt atagttctta
    70681 tcattatgat ataaaagtaa tgcacactct gttgcgcttc ctatatattt aaatgaatta
    70741 tcttcttttt ctatatctgc agttgaattt actatacagt tttgttcaaa atagctatta
    70801 ctttgatact ctcctccact tatatattta ccatcaacat atgctacctc taccatcatt
    70861 ttgttttgtg ttaaagtccc tgttttgtcg gaacatatta cagaaacaga acctatagtt
    70921 tcacaggctt ctttctttgt tactaatgca tttatctttg ccatcttttg cattgttata
    70981 gctaaggtaa tatttatcat agttggcaaa ccttctggaa cagttgcaac tattaatgca
    71041 atacaaacca tatatgcatt tttagcaggt tctaatgatt gtaagaaaga taatatactg
    71101 cttgtatcta aaattaacat accttttctc tgcatctgta taatcataaa catacacaat
    71161 aaagtagcta ttatgcctga tattcctgct attttagcac ccaacttccc taatttaatt
    71221 tgaagtggag tttgctggtc ttcatttgat aaattctgtg ctatcttacc catctctgtc
    71281 ttatcaccag tatgagtgac aaccattatg cccctaccat atgctacaag agtccctcca
    71341 aataccatat tgacttgctt tgcaggtatt gcatcctgtt cgattatttc tgttttagaa
    71401 taaactactt ccatatctaa tacagcatca gcattcttag ctacatcatc agattctcct
    71461 gttagcatat cttctctaag tttcaaattt atagactgta taagtcttcc atctgctggt
    71521 atcatatccc cagtttctat atatacaata tctcctggta ctaaatcatt ttttgatatt
    71581 ttaattatct tcccatttct aagcaccttt acttctatat tttctgttaa ttttgacagg
    71641 gcatgagctg cttttttaga ttttccttca gttattatgc ctatagaaat tccaataaaa
    71701 atagccccta aaatacctaa tgcgtcatgt aattctccca caaaagaact tattactgct
    71761 gctcctatga gaattaatat cataggttct gtcaaacttt ctcccaactc gtcccaaaat
    71821 gttctacctt cttttatagt aaattcattt aatccatatc taagcttcct ttcttctacc
    71881 tcattatcat caagtccaat ttctggattt gtttttaagt attttaatac ttctttggta
    71941 ggtttattat aatacctcat aactttatcc cccttgttaa ttatctataa ggaattatat
    72001 gcttatgata gcttgtatat tacttttcaa aaaaaataag gtgttgatta atcaacacct
    72061 tatagtggtt atatattatt aaattttatg ttacaggctt tataaattgt gagctataca
    72121 aatcaaaata tttaatcttc aaaataccct tctggatata atggaaactt agatataagt
    72181 tcttgtgcct ctgctttaca ttcatctaat acttctttat tatcaatatt ttctgctacc
    72241 ttattcatta tccctgctat ctgtataact tctttttctt tcagacctct ttgagatatt
    72301 gatgtaagac ctatacgaac accactagtt acaaatggtg attgtgggtc gtcaggtata
    72361 acatttttat taactgttat tcctacatat tcaagagctt tttcaaattg ttttcctgta
    72421 agattcttac ttcttaagtc aaccattact atatgattat cagtacctcc acttacaata
    72481 ctaaaaccat gtgaaatcag ttcagaagct agagtctgag catttactac aacttgctcc
    72541 attatctttt taaatttatc tgtacttaaa tataatagtg aaaaggcttt tgctgcaact
    72601 gtattaagat gtatagaacc taatgttcct ggaaaaacac ctttatcgag tttctttgca
    72661 tgttctgctt tacaaagtac aataccactt cttggtccac agaaagtctt tgtcgtagat
    72721 gaagaaacaa aatctgcata aggtacagga ctaggtatta ctttcgctgc gactaatcct
    72781 gcaacatgtg ccatatctac cataaagtaa gctcctactt cttttgcaac ctttgatatt
    72841 ctttcataat ctattaatct tggatatgaa cttgcccctg caattataag ttttggtcta
    72901 cattcttttg cctttgcttc aagagcatca taatctatac gtccagtatt tgggtctacc
    72961 ccataaaatt catatttata aatgtcatgt aaaaaattaa ctgcgctacc atgtgtcaag
    73021 tgtccacctt ggtcaagacg catacttaaa acagtgtcat ttggttttaa tattgatgaa
    73081 tatacacaat agttagctgt agaacctgaa tacggttgta cgtttacatg ttctgctcca
    73141 aatacttctt ttgcacgttt tattgctagg gtttcaagtt tatctgcttc ttcagaacct
    73201 gcttgaaaac gagcccctgg atagccttct tctgttttat ttgtaaatac acatccactt
    73261 aattcaagta cttctgttgg tgctgtactt tcagaagcta tcatctcaat attgtgttct
    73321 tgtctaacca actcatcagc tacaatcttg tataactctg ggtctgaaat ttttgttgtt
    73381 tttaacataa taatcctcct cttaattaaa gaatatattt tattagttta atcttcattg
    73441 ataaatttat tataacggtc tataaaacgt aagatattcc tccaccaggt cctaatggta
    73501 tgccaatacc catgaatagt aacaatatta ttatttctat taatgtaaat accactgagt
    73561 atggaatcat attcgatatg acagtaccta tacctatatc tttatcatat cttctggcaa
    73621 aggccaatat aactggaaaa tacggaaaaa gtggacttat tggatttgtt gaagcatctc
    73681 caatacgata agctatttga gttaatgctg gattaaagtc tagtagcata aacatgggaa
    73741 caaatatagg tgctaaaatc gcccattttg cagaagcact tcctacaaat aaattgataa
    73801 atccagatag caatataaat cctattatca atccatagct aggtattccc gactctgcta
    73861 gtaattttgc tcctgttatt gataaaattg ttcctaagtt actaagatta aataaattaa
    73921 taaactggga tgctataaat gctaggacta tatatccacc catatcactc atactactac
    73981 ccatcataga tactaaatct ttgtcacttt ttatcttctt acttactttt ccatacacta
    74041 atcctggagt taaaaatata atagtgatta taggaactat acctttcatt aaaggtgcat
    74101 tactagatag tatagaacca gtctctggat ctttcataaa tgcattgtca cctatacata
    74161 aggcaactat cactactact acaactaaca atgataataa agcgtatttt atacccttat
    74221 tttcaagttc actcaattcc tgtatatcct tatcatttgt tgaatcatta tattttgtaa
    74281 aacgaggagc tataaatttt tcagttacaa atgctcctgc aaaagttaaa actatcgctg
    74341 atataaaagc aaaataaaga ttcattgctg gattgccttg gtaagatggg tccatcattt
    74401 gagctgctgg tattgtaaat ccagctaaca atacatctgt agtactaagc ataacatttg
    74461 ctgcaaatcc ccctgcaaca cctgcaaaag ctgcaaacat acctacaaga ggatgtcttc
    74521 caattcctaa aaacacaagt gctgcaagtg gtggtaatat tataaatcct acatctgctg
    74581 ctgtatgtga caacatacct gcaaatacga ttgctacagt tacaagtttt tgtggaactt
    74641 tacttatacc ctttttcatt aacacttcca taaatccaga tttctcagca acacctgctc
    74701 caagcattgt aaccagtact aatcctaaag gagcaaatga ctgaaagttt gtaactatgc
    74761 tacctaaata tgattgaatc tgctctttct ctagtagatt tactaccttt acaacttctt
    74821 ttgtagaagg atgtatttct tctactccta aattagatat aactgctgac aatattacaa
    74881 caattataca tagtaataaa aatatggtta ctgggtctgg aagtttattt cctgctctct
    74941 ctacaacatt tagtgccctc atcaataatc cactatcttt gtttttttcc tgtgaattaa
    75001 ttttcctcaa actaataccc cctcataaac tttatctcca gaatgctcta tcttaaattt
    75061 tattttttaa tttatccata taatttataa cagactgaca tagtacattt gtacctacca
    75121 atatagaatt tttatcagct ttaaatttag gattatgcca ctgatatata caatcttgtt
    75181 ctttgttgcc tacccctaac cagtaaaaaa atcctggggc tttttccatg aatatagaaa
    75241 aatcttcccc tcctgtagaa ggtattggat caactatagc atcttctgaa tacaaatcac
    75301 acacagactt acaagctatt gcgtacatct ctttactatt tataacagct ggtaaatcaa
    75361 ataaataatc tagctttgca gttgcttgat atccacgagc tatctcacaa actatatttt
    75421 ctaaattttc tgatattttc tttcgtactt cattactaaa gcttctacat gtgcctgtca
    75481 tatctacctt ttctgaaatt acattatttg cagtccctcc atttatagta cctattgata
    75541 taacagctga ttctaatgga cttatgtttc tgcttactat ggtttgaata cccattataa
    75601 ttgcacttga tgctactata gggtctattg ttctgttggg tatacctccg tgacctccaa
    75661 atccatttac ttctatctta atagtgtcta ctgctgccat taacccacct aacttaacac
    75721 ctatttttcc acaaggtata tctggatgat tatgaagtcc aaatatagca tcaacttttg
    75781 gattttccat tactcctcgt tccactagca tcttcgcacc tttattgact tcttcggctg
    75841 gttgaaatat aaactttaca tttccatgaa gactatctct aatatgagac aatacatatg
    75901 cacatcctac aaggcaagac gtgtgtatat catgcccaca tgcatgcatt ataccatcat
    75961 atctggattt atacttaata tcaacctctt catatattgg caatgcatca atatctcctc
    76021 ttagtgctac tgtgggacca tcatacttcc cttttaataa tccaacaact cctgtttcca
    76081 ttcctaaatc taatatttct atgtctaaac tcactaataa atcttttata gcttttgtag
    76141 tcctaaattc tttaaaactt aattcggggt gcatatgaat atctgtaaaa aaatctaaaa
    76201 tatcttcttt atacttttct gagattaaaa taagttcatg catactaaca cctctccaaa
    76261 atttta
//
LOCUS       DAYAOO010000006        73868 bp    DNA     linear   BCT 12-OCT-2024
DEFINITION  TPA_asm: Clostridioides difficile isolate ST8-SSI-h139-18
            SAMN40601845-rid21577343.denovo.006, whole genome shotgun sequence.
ACCESSION   DAYAOO010000006 DAYAOO010000000
VERSION     DAYAOO010000006.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN40601845
            Sequence Read Archive: SRR28438827
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 73868)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 73868)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-MAY-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-MAY-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002157583.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002157583.1
            Genome Coverage       :: 163x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/11/2024 16:19:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 4,038
            CDSs (total)                      :: 3,963
            Genes (coding)                    :: 3,930
            CDSs (with protein)               :: 3,930
            Genes (RNA)                       :: 75
            rRNAs                             :: 6, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 60
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 33
            CDSs (without protein)            :: 33
            Pseudo Genes (ambiguous residues) :: 0 of 33
            Pseudo Genes (frameshifted)       :: 7 of 33
            Pseudo Genes (incomplete)         :: 25 of 33
            Pseudo Genes (internal stop)      :: 11 of 33
            Pseudo Genes (multiple problems)  :: 8 of 33
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..73868
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN40601845-rid21577343.denovo.006"
                     /isolate="ST8-SSI-h139-18"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Denmark"
                     /collection_date="2018"
                     /collected_by="Statens Serum Institute"
     gene            complement(542..1183)
                     /locus_tag="ACGI5H_000473"
     CDS             complement(542..1183)
                     /locus_tag="ACGI5H_000473"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902140.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA];
                     GO_function: GO:0016657 - obsolete oxidoreductase
                     activity, acting on NAD(P)H, nitrogenous group as acceptor
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="nitroreductase"
                     /protein_id="HFG9696204.1"
                     /translation="MNNNFQDNQTINLIQSRRSIRKFTTEQISDEQVNTLLHCAFAAP
                     SGCNKQPWHITVVQDQKLLKEISDDTLSRIHEVSNVEINKNFKLFYGAPTVLFISYDE
                     SSSWAPYDIGILTGNITTAAQALGLGSCIIGMVRGLFTPVEQGDIEGLVSVLDKEDVK
                     ESESIKMKFDTNKKYRELLDIPEGYSVPFGIAVGIPDGNLPNAREVVYKVSRV"
     gene            complement(1426..2229)
                     /locus_tag="ACGI5H_000474"
     CDS             complement(1426..2229)
                     /locus_tag="ACGI5H_000474"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860949.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prepilin-type N-terminal cleavage/methylation
                     domain-containing protein"
                     /protein_id="HFG9696205.1"
                     /translation="MNKKGFTLIELLVVISIIGILVIVAVPALFRNIEKSKAVTCLSN
                     RENIKTQIVIAMAEESSKGKNEVMKEVLENKDGKYFETEPKCKSGGIYSATFDDGYDG
                     ITGIESIAKVYVTCTKHPDGVEMARDIHQSMKDLIASFAQDPSIIPGASKGNDDFRKY
                     LLDNKYKNGWPTIPDEFKAKYGLSKDTLYIQPYAYNPTKSDATVVVFANNKTGGNWYT
                     SLVYDYDEGRWYKGKNGISVAGRSWDVDTDSVKSVKTEIHSKEGWGPLN"
     gene            complement(2385..3560)
                     /gene="thiI"
                     /locus_tag="ACGI5H_000475"
     CDS             complement(2385..3560)
                     /gene="thiI"
                     /locus_tag="ACGI5H_000475"
                     /EC_number="2.8.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437440.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0140741 - tRNA-uracil-4 sulfurtransferase
                     activity [Evidence IEA];
                     GO_process: GO:0006400 - tRNA modification [Evidence IEA];
                     GO_process: GO:0009228 - thiamine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA uracil 4-sulfurtransferase ThiI"
                     /protein_id="HFG9696206.1"
                     /translation="MVYNILIVKYGEIGVKGKNRYIFENRLIRNIRNMLKPIGRFNVY
                     KEYGRIYVDLEDYDYEEVIEEVRKVFGIVGVCPGVRAKKDYDTLKEIALKMLEEKIEA
                     GYKTFKVESRRGDKSFGLTSQEMSMDIGGYLLSKVGDRINVDVRNPEVKIKCEYREFH
                     TMVYSDTIPGYGGLPLGTNGRAMSLLSGGIDSPVATWMVAKRGMEVEAVHFHSYPFTS
                     ERSQEKVKDLAKILAKYCGRVRLHKVNILEIQKAIGENCNEEESTILSRRFMMRIAQR
                     LSEKRHCDALITGESIGQVASQTIQGLTCTNAVVDLPVFRPLIAMDKSDIVDIAKKIG
                     TFETSIVPEEDCCSVFSPRKPVTKPRLEKIEKSETALDIEKLVQDAIDKIEVEDIEF"
     gene            complement(3606..4757)
                     /locus_tag="ACGI5H_000476"
     CDS             complement(3606..4757)
                     /locus_tag="ACGI5H_000476"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902136.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine desulfurase family protein"
                     /protein_id="HFG9696207.1"
                     /translation="MEIYLDNSATTKPYQEVIDKMVYALNTEYGNPSSVHRKGVEVEK
                     AIKEVRQDIAKSLGAKEKEIYFTSGGTECNNTIIRGITSLNKKRKNHIISTNIEHPSV
                     LNTLKDLEEDGFEVTYLEVGKDGKINIEDLKNAIKSTTCLVSMMHVNNEIGTIQPIGE
                     VGKYLKGLKEKIYFHVDAIQSYGKINFRPSKYNIDFMSVSAHKFHGPKGIGFMYIKEN
                     NRLKPMLTGGGQEIGIRSGTENVPGIYGLGEAVRILNKDLDAVISKVDNLKNILKNEI
                     IDNIEDIKINSPEDGVCHILNVSFRGTKGEVLLHYLEQKGIYVSTGSACSSKKKGSYV
                     LNAIGLTNEEINGTIRFSLSDMNTEEEMLEAVKVLKESICDLRSIMKRK"
     gene            complement(5404..6126)
                     /locus_tag="ACGI5H_000477"
     CDS             complement(5404..6126)
                     /locus_tag="ACGI5H_000477"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860947.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HFG9696208.1"
                     /translation="MITIKNLSKSFGDLNVLKNIDLEIAKGEIMVIVGPSGSGKSTLL
                     RCMNLLEIPTGGEIIFEGKNLVDKKTNIDEVRQNIGMVFQNFNLFPHKTILDNITLAP
                     IKLKKMTKEEAEKKAEILLSRVGLLDKKDSYPSQLSGGQKQRIAIARALAMEPDMMLF
                     DEPTSALDPEMVNEVLDVIKELAKEGMTMAIVTHEMGFAKEVADRVIFIDGGSILEDN
                     TPEEVFGNPKHERTKAFLAKVL"
     gene            complement(6185..6862)
                     /locus_tag="ACGI5H_000478"
     CDS             complement(6185..6862)
                     /locus_tag="ACGI5H_000478"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888558.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA];
                     GO_process: GO:0006865 - amino acid transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HFG9696209.1"
                     /translation="MSLDFSFLSRFGTSFLEGTGVTVSISLVALCFGFIIGIIICMAK
                     ISKSKVLRAISSIYIEVLRGTPLLVQIYIVWFGLPQLGIRFPMLFGIPSEFIASAFAL
                     SVNSGAYVAEILRSGIQSVDNGQMEASRSLGLNYWSTMRYIIIPQAIKNILPSLANEF
                     ITLVKESSIISVIGVVEIMRTADIVKNAAFRALEPLIVAAAIYFVITFTLSRLVGLLE
                     KKLSVSN"
     gene            complement(6890..7705)
                     /locus_tag="ACGI5H_000479"
     CDS             complement(6890..7705)
                     /locus_tag="ACGI5H_000479"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418392.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transporter substrate-binding domain-containing
                     protein"
                     /protein_id="HFG9696210.1"
                     /translation="MKVFKKLLSLGLVLGLTLSLVGCSGGGEKTKLEQIKDNGKLVVG
                     TSAEFPPFEFHKVVDGKDSIKGFDIMLAEEFAKELGVKVEIKDMSFDGLIGALNADQV
                     DIVLAGMSPTPEREKSVDFSELYYLSRNAVIVKDADIDKVKTEDDLKKLRVGVQAGSI
                     QEEYVVNTLKMTTTKSLKAIPDLITELKNGNIDAVVTNEAVSLINVKKYDGIKMANTE
                     VGKDVTEGMAAAIKKSDNNKDFIELLNKKIKELQDGKKIEEFLNEASTEAASN"
     misc_binding    complement(7931..8141)
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            complement(8859..10925)
                     /locus_tag="ACGI5H_000480"
     CDS             complement(8859..10925)
                     /locus_tag="ACGI5H_000480"
                     /EC_number="3.6.4.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888557.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0004386 - helicase activity [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent helicase"
                     /protein_id="HFG9696211.1"
                     /translation="MVELIITTNIDIRKLNENQLEAVEHIDGPCMILAGPGSGKTRVI
                     TYRIANMVVNKNIAPTRILAISFTKASSIEMKNRALNLSDDIRLNKVTYGTFHSVFFK
                     ILRYFERYNLDSIFDEKSKRMTIKAILKSLNIENADDDENIGQVINEISYVKNELMDK
                     NEFNSEVLTKDEFLKVYNLYEEQKSKVNKIDFDDMLIRTYYLLLNNKSALEMVRNVYK
                     YILIDEFQDINKVQFEVLKLICSPLNNIFAVGDEDQSIYGFRGARPDFLLEFEQYFNN
                     TKKIILDINYRSKSEIVHTANRLIDKNKNRYEKIIKCSQGDGGSVTYISPHDSEEEAL
                     YIAREIIDEIQKDYVEYSDFAVIYRTNIQSRALVDVFMDMRIPFVVKDSVITIYDHWA
                     SQDILAYLRIGINPKSNKDWLRIINKPFRYISKDSINMVKDEKDFITALINKCNLHPK
                     QVKTINDLEIDLSYLNTLNPKNAISYIRTSLDYDRYVLDYCSNRKIKTNGLVEILNEL
                     ESSATNFNTVTEFLEHIDRVKTELTENNKNKQTEGVIFTTMHSAKGLEFRNVYIIGVN
                     EGTIPHEKSYDICKEEKKEEQLEEERRLMYVAITRAEEKLCISSTLNKYGKKVDKSLF
                     INDIKSPTKKEIDSIGVGDKVYHKKFHEGEIIKKDGIMFTIKFKDRERILDLKTCLLK
                     NIIYTI"
     gene            complement(11002..14031)
                     /locus_tag="ACGI5H_000481"
     CDS             complement(11002..14031)
                     /locus_tag="ACGI5H_000481"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418390.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EAL domain-containing protein"
                     /protein_id="HFG9696212.1"
                     /translation="MENNLRKNNSIMKKMIFPLIIVMLIQTSLFCATILWGGTIKKLN
                     DNSFDILNERVINRKNYIQNEMLQRWSNTSETEATINSSVKKVLNEKNALIEDVGNNE
                     EINKDIIKSISNDLIYLLRKNSVTGAFIILSDKNINDKSIDSKGEISRTGLYIRDLDP
                     KFNPNDNSDLLIERGSSDIARSFGISMDSYWEPKFSFKSENEQDGDDFFYKPFRAAID
                     NPNVSSSNLGYWGSKFLLTNAGDRLMTYTVPLIYEDGTVYGVLGIDLSVNYLRELLPY
                     SEINGNKKGNYILGVDRNNDMAFENVISNGYSLKEKFWDGLHSNLEQKESYKNIYKIK
                     NKDNECGNGNIYASVQYLDLYNSNTPFENERWALLGIIEEKSLLSFSKRVEKLVIISI
                     AISLLIGLIGIYIASRLFTKPIVLLANKVRNSNPSKPVNLDKINISEIDELSSAIELL
                     SANVADSSSKLSQIIEMVDMPIGAFELYKNAENVFCTKEFFSVFTTEIKFEEYGYMEK
                     NKFLKKLRGLDKYLQESYETENTYIYKFESKDKKLKWIRMNIFEDELKVLGVVVDVTK
                     EFIEKRKIEYERDFDILTNLLNRRAFHSQIQEKFKNKDELKIAAFIMWDLDNLKYIND
                     TYGHDAGDEYIRCAADILKKFISWNGIVSRLSGDEFYVFIYGYESKDSIRDIINSVKK
                     QMNNTLLKLHDGTEFKIRASAGISWYPDDSTNYDELMRYADFAMYQIKNTIKGEVSEF
                     DINIYNKDSFLLSNREELNKLIDGQLVEYAFQPIVDCKGKVFAYEALMRPKIKTFSSP
                     IDVIRLARSQSKLYQIERITWFKALKSFKKYKEKFGDCKLFLNSIPNNNLSKVDFEEI
                     EDLYGEYLNRVVLEITENDKINEDFIEKKKAYIDHWNIEIALDDFGTGYNGDAVLLYI
                     MPDYVKIDMSIVRGIDKDENRQKILKNLISYSNERNIKVIAEGVETKGEMETLINLGV
                     DYMQGYYISKPSFIPEDISDKIKKELKICHENRNDVV"
     gene            complement(14084..15544)
                     /locus_tag="ACGI5H_000482"
     CDS             complement(14084..15544)
                     /locus_tag="ACGI5H_000482"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888556.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
                     /protein_id="HFG9696213.1"
                     /translation="MNRCKFAKLIITSMIVLLLTGCSLKKEDNYKLDPENPTSIQIWH
                     YYNGQQKMAFDKLVKEFNDTVGAEKGIIVEAFSQGNVVDLSEKVLDSANKKVGSEDVP
                     NIFAAYSDTAYEMDKLGLLVDMDKYISKEELNEYIDEYVEEGRINSKDEFKLFPIAKS
                     TEILMLNKTDWDKFAKATNSNINDIKTIEGLVETSKKYYEWTDSLTKEPNDGKAFFGR
                     DALANYIIIGSKQLGVEIFSVKDGKVTLNIDEKVMKKLWDNFYVPYINGYFASYGKFR
                     SDDAKTGDILALVGSSSGAAYFPDRVMLNDNESYNIETSVFQAPRFKGEGKYAVQQGA
                     GMAVTKSTKEEEYASVEFLKWFTDKEPNIKFSIASGYLPVKKKTNDLDVIKEVMKKDN
                     LSLSDKVEGSIASSIEQINSCNLYTNKAFDGGTKARQILEYSMLDKAKEDSNKINELV
                     KSGTSKKDAVAQFNNDKNFKTWFESFKAELENAIKK"
     gene            complement(15636..16010)
                     /locus_tag="ACGI5H_000483"
     CDS             complement(15636..16010)
                     /locus_tag="ACGI5H_000483"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860944.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9696214.1"
                     /translation="MGNKNKNTKYKDKTRERYNKKVENLNKEKLNKINKQSKKVDKID
                     DIINKSSIVLCVLLVVFSLLYLFKLVQLNIIMILLVITVAIQQGLVSFGAFRNKNYVK
                     ALFSIFVIVCFLIAFKYVVNPV"
     gene            complement(16186..16926)
                     /locus_tag="ACGI5H_000484"
     CDS             complement(16186..16926)
                     /locus_tag="ACGI5H_000484"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902133.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar motor protein MotB"
                     /protein_id="HFG9696215.1"
                     /translation="MLYDEDEKEENNERWLLTYSDLITLLMIFFVIMYSMSNVDAEKY
                     KQLSQSLNSAFGGSSGVIEGGNSKIEPVVEPGSNDLDTLQNAKFKKIGEEIQKYLNEN
                     GMANSVSLRVQDRGLVISLKDTILFDTGKAIVKDNSRDKIIQIGKMLNEMNSYMRVEG
                     HTDNMSIKNSEFKSNWDLSVMRATNVVQLLIDNAGIAPDKLSAVGYGEFRPIAENSSE
                     EGRSKNRRVDIVLVDSKYDNVENVSKDK"
     gene            complement(16947..17735)
                     /locus_tag="ACGI5H_000485"
     CDS             complement(16947..17735)
                     /locus_tag="ACGI5H_000485"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888553.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar motor protein"
                     /protein_id="HFG9696216.1"
                     /translation="MTTLIFFIVGIASLVVAFVIDGGHVGALFVFSSALVVFGGTIGA
                     VGASTPFPVFKKSIKIMLLAFKNKKPNNIENIIYFKEIATKARKEGLLSIDKEISEND
                     ELDPFIRKGLELMVDGVDAVTIRNILESQIQITSKRHKEGIAIFDSAGGYAPTLGIIG
                     TVMGLVHILGNLSSNPDALGPQISVAFLATLYGVGSANLIWLPIASKLKAINQQEVSE
                     RLLVIEAILSILEGDNSNLMTEKLKIFLNSKELIELEEIGGRAE"
     gene            complement(17823..17913)
                     /locus_tag="ACGI5H_000486"
     tRNA            complement(17823..17913)
                     /locus_tag="ACGI5H_000486"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(17877..17879),aa:Ser,seq:gct)
     gene            18172..18936
                     /locus_tag="ACGI5H_000487"
     CDS             18172..18936
                     /locus_tag="ACGI5H_000487"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418385.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR family DNA-binding transcription
                     regulator"
                     /protein_id="HFG9696217.1"
                     /translation="MLPQERYEKILSILKSDNIIKINDIVQMFDISIETARRDLAHME
                     SIGLLKRVYGGAIPVIASSVELNYVKRKKINSNDKKQIAIKCSEFINTNDTIFMDTGT
                     TVLEVSKNLKDKKNLTVITNSILVANELMNTNIKVYVLGGYLRETEGSFSGPLTLSAI
                     EQFNVDKAILGAGGITLENGISDYHLEEALVRKKMIERSRKSIVVVEPPKFGINSFAS
                     VAPIEHIDTIITSASIDHNIIIEFSQKGIPLVIADN"
     gene            complement(19217..20344)
                     /locus_tag="ACGI5H_000488"
     CDS             complement(19217..20344)
                     /locus_tag="ACGI5H_000488"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860941.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ethanolamine utilization protein EutH"
                     /protein_id="HFG9696218.1"
                     /translation="MPFDKIILYIMAVGVLLGALDRIIGNKFGLGERFEEGFNSMGPL
                     ALGMVGIVCLAPVISDVLGPIIIPIFNLCGADPSMFATILANDMGGYPLAMELAHNKE
                     AGMLAGLVVSSMLGCTLVFSIPVGLGLIEYEDRPFFAKGLLIGLITIPFGGIIGGLIA
                     GFNLSMVIINMIPVIILAVILAVILAVGLKFNSTLMINGSLIFGKFISILITIGLGAA
                     AFQEITGIVLIKGMTPIREGIQVIGSIAIVLLGTFPILHLLVKVLNKPLTIVGGKLGM
                     DATSAAGLVFTLANSIPVYKMMKDMSPKGKVVNTAWLVCATAALGDHLGFTAGVVPEM
                     ITPVVIGKLVGGVLAIALAILMTKDLTLEEEQSIKMKKDAV"
     gene            complement(20385..21911)
                     /gene="glpK"
                     /locus_tag="ACGI5H_000489"
     CDS             complement(20385..21911)
                     /gene="glpK"
                     /locus_tag="ACGI5H_000489"
                     /EC_number="2.7.1.30"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003432232.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004370 - glycerol kinase activity
                     [Evidence IEA];
                     GO_process: GO:0006072 - glycerol-3-phosphate metabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycerol kinase GlpK"
                     /protein_id="HFG9696219.1"
                     /translation="MKYVLAIDQGTTGTRAVLINEKSEFVFSDYMEHTQIYPQSGYVE
                     HDPIEIWNNTKTVSNNVLQQAFENGINESDIKGIGIDNQGETVMLWDKNTGKPLYNAI
                     VWQCRRTYDYVENLKNIPGLENKIIDKTGLIIDPYFSGTKIKWVIDNVKGVKEKIKNG
                     EVLAGTLDSWLIWKMTGGKSFLTDVSTAARTMLFNIRDMDWDRELLDIIGVPRSILAD
                     IMPTSGDFGTTDKEAFCGVSIKITASMVDQPAALFGNGCFEPGMVKNTYGTGCFLYMN
                     IGEELNIAGNGILTTVAWKIGDKVTYAYDGGVYIAGAAIQWLRDGIGVIKNYSETDDM
                     ANSISSTGGVYFVPAFAGIAAPYWDQYARGTMVGITGSTKKEHIVRATLESVALQVKD
                     VVDSMNLASGKKIKMLRVDGGITKNNFTMQFQSDILGIPIEIAENPETTVLGVGYMAG
                     LSCGVWNSIDEIRSEFTISKKYIPNMTTQKREEILLGWNQAVKRAMNWENDTKKVCAN
                     "
     gene            22204..23301
                     /locus_tag="ACGI5H_000490"
     CDS             22204..23301
                     /locus_tag="ACGI5H_000490"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418382.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminotransferase class V-fold PLP-dependent
                     enzyme"
                     /protein_id="HFG9696220.1"
                     /translation="MKKTYLFSPGPVMVTDKVRNSLLHYDICHRGNEFMDLFKDTQQK
                     INKLYNATSNYYSLIVSGSGTSVNECVLSSIFDKEDAVLLVSNGVFGERLEEILSTYN
                     VKTYKPNFEWAEYPDLDILEKYIIENSDIKVIAMVFHETSSGMINPVPELGKLAKKYN
                     KIFFVDAISASAGEYIDVEEFNIDIITGVGGKALGAFPGSAYLCAKESILQNIKENQC
                     KNVYLNLYKHYKVAKSSSQTPNTPNVTLIFALNEALTEFLEDDSKIERYKECSAILRY
                     GMEELGLTFLLPDKYMSNTVTSVFLPKEINVNEFILGLERESGYVVYPGKGKFLDANI
                     FQVANMGEIYPEDCYKFLDILKSKLEIKKVI"
     gene            complement(23792..24304)
                     /locus_tag="ACGI5H_000491"
     CDS             complement(23792..24304)
                     /locus_tag="ACGI5H_000491"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436941.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9696221.1"
                     /translation="MKVKKFKSGIVMALTVMAIGASLTNVSAMELNKSKEFETKYNEM
                     KRDFQEEYGKEDKFNITLDDEFTKEEVNGAKGIIKTTNKMNNEVVVLNYFDEMKSGIE
                     FELKPKAEKNAILRDEFQQGYGKEDKFKVVLDDEFTKEEVNGAKGIIKTTDKETGEVI
                     VYNYFDELEK"
     gene            24857..25738
                     /locus_tag="ACGI5H_000492"
     CDS             24857..25738
                     /locus_tag="ACGI5H_000492"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729426.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4300 family protein"
                     /protein_id="HFG9696222.1"
                     /translation="MKKRLIIMILSVVLVLSSILTIFAYSNIKYNNNKLIYSNMIDKK
                     TQNSVKEILKENKINEKDIDTFIKSVNNYNKLQVKILQNNINISKSGYSSINAKQVPY
                     NLEKLQDNWVKKFPDYMDVNCRITAFRLFKDFINSNKKFTGDSIDLNVDLDTIMNNKD
                     AKFSTKDVEKFINFFSAIPAKDTDDTIKIAEQIKNEWKKRKISFKNNKNISIINGFLR
                     YPETKNVFIGHTGICIKTKNGILFLEKYGVTSPYQVTKFKNKEDVKNYMFNRLKMSEG
                     EIELPDPIIMENDKLMK"
     gene            complement(26051..26830)
                     /gene="hisJ"
                     /locus_tag="ACGI5H_000493"
     CDS             complement(26051..26830)
                     /gene="hisJ"
                     /locus_tag="ACGI5H_000493"
                     /EC_number="3.1.3.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902127.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004401 - histidinol-phosphatase activity
                     [Evidence IEA];
                     GO_process: GO:0000105 - L-histidine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="histidinol-phosphatase HisJ"
                     /protein_id="HFG9696223.1"
                     /translation="MKDGHIHSPYCPHGSKDDFEKYVQRAMDVGITEMTFTEHFPYAN
                     GFRDPAPENDSCMSIEDLPKYFNDVKKLKEKYEGKIKINVGSEVDFIEGYEEGIKENL
                     NKYGKELEDSLLSVHIIKIDDDYYCVDYSVEEFQNLIDKLGSIEAVYNKYYETLIKAV
                     NSDLGIHKPKRIGHLNLVRKFNQVFPYDYKGNKILEELIKLIKEKGYELDYNVSGNRK
                     EYCKEPYIDGYLLDLVKKYDIPLVLGSDSHCAEEINKYDII"
     gene            complement(27376..27726)
                     /locus_tag="ACGI5H_000494"
     CDS             complement(27376..27726)
                     /locus_tag="ACGI5H_000494"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418378.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc transporter"
                     /protein_id="HFG9696224.1"
                     /translation="MIFDKEIVRYHHGHHDHDHCHEHTHGDICHEHPHDHAHDHDHEH
                     SHEESSESKDEKTLKILLVHWINHNETHEEGFREWVEKARAIGKEETAKSIEKAIEYM
                     EEANKMLLEAKKHM"
     gene            complement(27742..28158)
                     /locus_tag="ACGI5H_000495"
     CDS             complement(27742..28158)
                     /locus_tag="ACGI5H_000495"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418377.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3842 family protein"
                     /protein_id="HFG9696225.1"
                     /translation="MIIAVIDGMGGGIGAQIVSSLREELPTYVEIYALGTNSIATSSM
                     MKAHANKGATGENAIVVSAKKANIIVAPISVIIPNSMMGEVTCNISEAIADSEALKIL
                     LPIMPENVELVGLEGKPLALLVKDSVNLIKKEFNIK"
     gene            complement(28177..28368)
                     /locus_tag="ACGI5H_000496"
     CDS             complement(28177..28368)
                     /locus_tag="ACGI5H_000496"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418375.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CooT family nickel-binding protein"
                     /protein_id="HFG9696226.1"
                     /translation="MCESSAFICKSNNELEKVMENVVNIDPCDGKIYLTDLLGEQKII
                     DGIIKEIRLMDHKIIIQEN"
     gene            complement(28519..29334)
                     /locus_tag="ACGI5H_000497"
     CDS             complement(28519..29334)
                     /locus_tag="ACGI5H_000497"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="biotin/lipoate A/B protein ligase family
                     protein"
                     /protein_id="HFG9696227.1"
                     /translation="MNQWRVIHNKSYEGAMNMAIDEAIFTAYKKGHNKPTLRFYTWEP
                     ACLSIGYFQKLEDEIDLDKCRCMNIDYTRRITGGRAVLHDNELTYSIIIGEDNPLIDK
                     SINLSYRYISEGLVKGLNLSGIETDNLNRGERISRENLSAACFNAHASYEVTINNKKV
                     IGSAQSRKDGVLLQHGSIILDFDVEKLFKLIKTKTPELKERAMKFTAKKASGIENEIG
                     RKIDIDILQKNIVKGLAEQFNVEFVEGDLTDYEKQLVKELYEKYKNEEYNKKR"
     gene            complement(29381..30319)
                     /locus_tag="ACGI5H_000498"
     CDS             complement(29381..30319)
                     /locus_tag="ACGI5H_000498"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729428.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="radical SAM protein"
                     /protein_id="HFG9696228.1"
                     /translation="MIRLSVGTAIELGILNKKSDIPPTTAYIMIGEKCINKCSFCSQS
                     IESSTRKDKLSRVIWPEFSKEEILDALKAYKGKNIKRICIQSMASEEAHNSVLDFINY
                     ISGKIDMPISLSAKLENDEQIKKFFSAGVDKIGIAIDAANKELYEKIKGNNYDEKLKF
                     ITEMSKSYPNKISTHIIVGMGESHEDIYNLYTYLKENDVTISLFAFTPVRGTKMEKIN
                     QPSIESYRRVQLMSYMINKGYPKEYFKFKNGYLNSIKLDNDILKDINKGYPFEIRGCK
                     DCNRPYYNERPGSTIYNYSRPLNQSEIDLAIREINL"
     gene            complement(30316..31188)
                     /locus_tag="ACGI5H_000499"
     CDS             complement(30316..31188)
                     /locus_tag="ACGI5H_000499"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418368.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="radical SAM protein"
                     /protein_id="HFG9696229.1"
                     /translation="MNKNLSEKMKIAFDIKLKNFGNKIEFAYPNQTLALSTTSNQCSL
                     KCAHCNGHYLNNMVPIEEYEEKVQSRNITSFLLSGGCSYEGDVPINTHINTIKNLKEQ
                     GYRLNAHLGLMDKDSIVELCKYLDIVSFDLVFDDETIREVYKMKKSKEDYIEVYNTIQ
                     EHTEVAPHICIGLKGGQIKGEYEIIEYLQKNPPNKLTFIVLIPTKGTEYENVEPPELE
                     GVADILCEARINLPDTEINLGCMRPRGVYRKELDQLSIMCGVNRIVLPSRSAKNKAIE
                     MNMTINECKECCVL"
     gene            complement(31213..33141)
                     /gene="acsV"
                     /locus_tag="ACGI5H_000500"
     CDS             complement(31213..33141)
                     /gene="acsV"
                     /locus_tag="ACGI5H_000500"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888540.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="corrinoid activation/regeneration protein AcsV"
                     /protein_id="HFG9696230.1"
                     /translation="MIKVSFTPNNKEVYCNEGDILLEVARNADIFIDAPCNGNVSCGK
                     CKVKLLNGKVDTEKTRHITDDEWEQGYILACCTKVISDIEIEVPSKVSSSMHGMKIEG
                     SNKKEDREIFERAKKIIEEHNLQFKTNIKKKYIEMEEPNLDDNISDVDRLERYVRNNL
                     GYNEIDFRLDILRKMPTVFRKSDFKVTITYVQKQKKLTIINIEQGNKENSLYGVAIDI
                     GTTSVVVCLVDLYSKEVVDKASSGNAQIKYGADVINRIIYSTKKNGLETLHKAIVEET
                     INPLLKTIYERNGIDKEDVVTLVAAGNTTMTSLFLGVYTDFLRQEPYIPPFLKSPKLM
                     GENVGLFVNDSAYVYLAPSVASYVGGDITAGVLSAGIWSSEENVLFIDLGTNGEIVFG
                     NKDYMMSCACSAGPAFEGGGISCGMRASAGAIEKVIIDKDTLEPTLKIIDECAPVGIC
                     GSGIIDLICQMITKGVIDRRGKIYRDLDNKRVRFNEHEIGEYVLAFKEEFDLENDIVV
                     NEVDIDNFIRAKGAIYSGAYTLVDSLGMDFSILDRVYIAGGIGNNLDIENSIIIGLLP
                     DIDREKFTYIGNSSLVGSYLALISKDAKNKLEEIGNQITYVELSVYPSYMDEFISACF
                     LPHTNIEQFPTAKKLLEE"
     gene            complement(33253..33630)
                     /gene="gcvH"
                     /locus_tag="ACGI5H_000501"
     CDS             complement(33253..33630)
                     /gene="gcvH"
                     /locus_tag="ACGI5H_000501"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418363.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005960 - glycine cleavage complex
                     [Evidence IEA];
                     GO_process: GO:0019464 - glycine decarboxylation via
                     glycine cleavage system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycine cleavage system protein GcvH"
                     /protein_id="HFG9696231.1"
                     /translation="MKLLPELKYSKDHEWVKVIDGDVVYIGITDYAQDQLGEILFVET
                     PEVEDTVTKGVDFGVVESSKVASDLISPVNGEVLEVNEKLEDEPECINEDPYENWILK
                     VKLADVAELDTLLSDKEYEAGLE"
     gene            complement(33717..35843)
                     /gene="acsB"
                     /locus_tag="ACGI5H_000502"
     CDS             complement(33717..35843)
                     /gene="acsB"
                     /locus_tag="ACGI5H_000502"
                     /EC_number="2.3.1.169"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418359.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA decarbonylase/synthase complex
                     subunit alpha/beta"
                     /protein_id="HFG9696232.1"
                     /translation="MNLYNIIFTGSEQALGAAQAMLAEAIEKNGKEHKVAFPDTAYSL
                     PCIYAATGQKMNTLGDLEGALEVVKSLINRTHLLEHAFNAGLATALAAEVIEALKYST
                     MDAPYSEPCAGHITDPIIRSLGVPLVTGDIPGVAVVLGECPDAESAAKVIKDYQSKGL
                     LTFLVGKVIDQAIEAGVKMGLELRVIPLGYDVTSVIHVVSVAVRAALIFGGLTPGDLN
                     GLLEYTANRVPAFVNAFGPLSELVVSAGAGAIALGFPVITDQTVLEVPMNLLTQKDYD
                     KIVATSLEARGIKIKVTEIPIPVSFAAAFEGERIRKSDMFAEFGGNRTEAWELVVKKE
                     ATEVEDHKIEIIGPNIDEVDADGVLRLPLAVIVKIAGKNMQEDFEPVLERRFHYFLNY
                     IEGVMHVGQRDMAWVRISKDAFDKGFRLEHIGEVLYAKMLDEFESVVDKCEITIITDA
                     EKVSELKGEAIAKYNARDERLASLVDESVDTFYSCNLCQSFAPAHVCVVTPERLGLCG
                     AVSWLDAKATKELDPTGPCQPIEKGECLDDRTGVWNSVNETVNQISQGAVESVTLYSI
                     LEDPMTSCGCFECICGIMPEANGFVVVNREFASVTPVGMTFGELASMTGGGVQTPGFM
                     GHGRHFISSKKFAYAEGGPERIVWMPKELKDYVADKLNATVKEMTGIENFCDMVCDET
                     IADDSEGVLAFLEEKGHPALAMESVM"
     gene            complement(35900..36706)
                     /gene="acsE"
                     /locus_tag="ACGI5H_000503"
     CDS             complement(35900..36706)
                     /gene="acsE"
                     /locus_tag="ACGI5H_000503"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418356.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbon monoxide dehydrogenase/acetyl-CoA
                     synthase methytransferase subunit"
                     /protein_id="HFG9696233.1"
                     /translation="MEKFMIIGERIHCISPSIRKALAERDPAPILKRAKEQLEAGAHY
                     IDFNIGPAERDGEEIMTWGIKLLQSEFNNVPIALDTANKKAIEAGLKVYDRTNAKPII
                     NSADAGSRFDLIDIAAEYEAMVIGLCAKEGIPRDNDERMAYCQEILEKGLMLGMEPTD
                     ILFDPLCLVIKGMQEKQVEVLEAIKMMTEMGLLTTGGLSNVSNGCPKHVRPVLDSAFL
                     AMAMANGFSSAIMNPCDPELMKTVKSCDIINGASLYADSFLELNEGGFAF"
     gene            complement(36756..38123)
                     /gene="acsC"
                     /locus_tag="ACGI5H_000504"
     CDS             complement(36756..38123)
                     /gene="acsC"
                     /locus_tag="ACGI5H_000504"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418353.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA decarbonylase/synthase complex
                     subunit gamma"
                     /protein_id="HFG9696234.1"
                     /translation="MALKALDIFKLTPKKNCKDCGFPTCMAFSMKVASGAVEVGKCPH
                     MSDDAIAKLSEATAPLMKALKVGAGASEYELGGETVLFRHEKTLVSRNRYAVSFCTCM
                     SDEAVDAKIANMKKVDYVRIGEQMKVEMAVLEYCGDKDAYLKLIDKIKGSGLEVAYIL
                     ACDDAQVVKEAVEVLKDARPMVYGATKENYKDMIEVVKGASLPLGVKAGSLEELYETV
                     ELIQAAGYKELVLDVTGENIKDTYTNAIQVRRTALKEQDRTFGYPSIVFANRLSNSNP
                     MMEVALSSIFTIKYGSIIVIDDISYAKALPLFALRQNIYTDPQRPMRVEPKIYPINNP
                     DENSPVLVTVDFALTYFIVAGDIERSKVPVWLVIPDAGGYSVLTSWAAGKFGGNSISA
                     FIKESKVEEVTNCKDLIIPGKVAVLKGDIEDNLPGWNVVIGPEESMELPKFLKGYQEK
                     ACQTN"
     gene            complement(38154..39098)
                     /gene="acsD"
                     /locus_tag="ACGI5H_000505"
     CDS             complement(38154..39098)
                     /gene="acsD"
                     /locus_tag="ACGI5H_000505"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003432254.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA decarbonylase/synthase complex
                     subunit delta"
                     /protein_id="HFG9696235.1"
                     /translation="MAFKMSTQKYSGKISEVEVGIGEKAIKLGGENVLPFYSFDGEVG
                     NSPKIGIQISDVYPESWTDSYKELYKDVANCPVEWAKYVEANTQADFICLKFDGSDPN
                     GLDKSVDECADVAKAVIEAIKLPLVVAGSGNHEKDGKLFEKLAQTLDGHNCLFMSAVE
                     DNYKGVGASAGMAYAHKVGAESSVDINLAKQLNVLLTQLGVKGENIVMNVGCSAVGYG
                     YEYVASTMDRIRLAAFGQNDKTLQMPIITPVAFEVGHVKEAIAPIEDEPDWGCPEERT
                     IAMEVSTAASVLVGGSNAVILRHPKSIETIKELVNALA"
     gene            complement(39118..39888)
                     /locus_tag="ACGI5H_000506"
     CDS             complement(39118..39888)
                     /locus_tag="ACGI5H_000506"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418348.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbon monoxide dehydrogenase accessory protein
                     CooC"
                     /protein_id="HFG9696236.1"
                     /translation="MGYNIAVAGKGGTGKTSLTGLLIDYLVKDKKGPVLVVDADANAN
                     INEVLGIEVEATIGEIREEVNQREKLGNAFPGGMTKAQYLQFRLNSIIEEGEGYDLLV
                     MGRSEGEGCYCFVNGILREQVNKISGHYKYLVMDNEAGMEHLSRKVTRHVDTLLLVSD
                     CSRRSIQAVARIRDLAEELKLSVGRILLIVNKVPNGVMNDGVKEEIEKHNLELIGVVP
                     MDELIYEYDSTGIPLVNLPEDSKSKVAMKEIFAKLELK"
     gene            complement(39944..41329)
                     /gene="lpdA"
                     /locus_tag="ACGI5H_000507"
     CDS             complement(39944..41329)
                     /gene="lpdA"
                     /locus_tag="ACGI5H_000507"
                     /EC_number="1.8.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003432255.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004148 - dihydrolipoyl dehydrogenase
                     activity [Evidence IEA];
                     GO_function: GO:0050660 - flavin adenine dinucleotide
                     binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrolipoyl dehydrogenase"
                     /protein_id="HFG9696237.1"
                     /translation="MKIVVVGGGPGGYVAAIKASMLGADVTVVEKRRVGGTCLNAGCI
                     PTKALLASSGVLNTVKEAKDFGIEIDGTIKPNFTAIMERKNKVVNQLISGIEFLFEKR
                     GVNLVNGFGKLIDKNTIEVTKDDGTVETIKADKIILANGSVPVVPRMFPYDGKVVITS
                     DEVLGLEEIPESMLIVGGGVIGCEIGQFFRALGTEVTIVEMVDQILLNEDKDVAKQLL
                     RQFKKDKIKVITGIGVQTCEVVDGKAVATLSNGKVIEAQYALVCVGRRPNLDNSGVED
                     IGIEMERGKVVVNEHLETNVEGIYAIGDIIDTPFLAHVASKEGIVAVENALGKTKVVD
                     YRAIPRCVYTEPEVAGVGKTEKQLEAEGVEYNVGQFDFRGLGKAQAIGHFQGFVKVIA
                     DKETDKIIGAAVVGPHATDLLTELSLAVHLGLTVEQVGDAIHPHPSLSEGLMEALHDV
                     HGECVHSVPKL"
     gene            complement(41373..42254)
                     /locus_tag="ACGI5H_000508"
     CDS             complement(41373..42254)
                     /locus_tag="ACGI5H_000508"
                     /EC_number="1.5.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729430.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004489 - methylenetetrahydrofolate
                     reductase (NAD(P)H) activity [Evidence IEA];
                     GO_process: GO:0006555 - methionine metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="methylenetetrahydrofolate reductase"
                     /protein_id="HFG9696238.1"
                     /translation="MSLLRETLESGKFAVTTEMAPPKGTDLSHLIECAKPLVGRVHAA
                     NVTDFQSAVMRATSLATCKLLKDAGLEPVIQITGRDRNRIAIQGEMLSAGVFGINNLL
                     ALTGDHTSVGDHPQAKGVFDLDSVGILQTAETLMAGTDMAGNKLKGSPDFYLGASVTP
                     EYSPIEVQLLKMKKKIKAGAKFFQTQALYDINTMRKFRELTRDMDCKVLAGIVPLKSP
                     GMAKFMTANVPGIFVPDEQIERLRAAGKENWVSEGIKMAGELIKQLKEEDLCDGVHIM
                     AIGAEENIPAILDAAGL"
     gene            complement(42289..42963)
                     /locus_tag="ACGI5H_000509"
     CDS             complement(42289..42963)
                     /locus_tag="ACGI5H_000509"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003432263.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methylenetetrahydrofolate reductase C-terminal
                     domain-containing protein"
                     /protein_id="HFG9696239.1"
                     /translation="MIISENKPLEEVLGYLKDFDKLVLVGCNQCAATCKSGGEEEVLK
                     MKETLEGEGKKILGYVMLDPACNLLKSKKDLKALKEETKEADAVLSLACGDGTQTIVK
                     NLKDKPVYPANNTLFIGEVQRVGEYEEACKACGDCELGWTGGICPVTMCAKGLMNGAC
                     GGAKNGKCEVNSENDCAWIKIYERLEAIGQLDNLAEIRPPKDYSKQNNPRSLSAKKKK
                     EAAANS"
     gene            complement(43000..43872)
                     /locus_tag="ACGI5H_000510"
     CDS             complement(43000..43872)
                     /locus_tag="ACGI5H_000510"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003432264.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional 5,10-methylenetetrahydrofolate
                     dehydrogenase/5,10-methenyltetrahydrofolate
                     cyclohydrolase"
                     /protein_id="HFG9696240.1"
                     /translation="MEGMSTKGQIIKGKPVADKISEELIKEVDLLIKEGINPKLTIVR
                     VGARSDDLSYERGALKRCQNIGITTEVLELAEDITQEEYIDVLKRVNDDKNVNGILCF
                     RPLPKHLNEEVIKYVIAPEKDVDCFSPINSAKVMEGDKSGFPPCTPTAVVEILKHYNV
                     DLKGSKVTVLGRSMVVGKPVSMLLLSEHATVTICHSKTKNLSGVAAEADVLIAAIGRA
                     KMVDESFVKDGAVVIDVGINVDEEGNLCGDVDTNAVLDKVSMITPVPAGVGSVTTSIL
                     AKHVVKACKLQNNK"
     gene            complement(43964..44596)
                     /locus_tag="ACGI5H_000511"
     CDS             complement(43964..44596)
                     /locus_tag="ACGI5H_000511"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418328.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003824 - catalytic activity [Evidence
                     IEA];
                     GO_process: GO:0044237 - cellular metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cyclodeaminase/cyclohydrolase family protein"
                     /protein_id="HFG9696241.1"
                     /translation="MKIADKTCVDFVEVLSSKEAVPGGGGAAALVGAIGMALGSMVCN
                     LTIGKKKYAEYEESVKEILSKAGKLEKDLLKMIDDDAECFLPLSKAYGLPKETEEEKR
                     IKAETMEKALKVACEVPLNIVRVCYEAIKLHEDLVDKGSRLAISDVGVGVQCLRAAIL
                     GGQLNVVININSIQDKEYVNKVKTEVDKLVEDGVKICDEVYAKVEKALGK"
     gene            complement(44701..46377)
                     /locus_tag="ACGI5H_000512"
     CDS             complement(44701..46377)
                     /locus_tag="ACGI5H_000512"
                     /EC_number="6.3.4.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014355320.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004329 - formate-tetrahydrofolate ligase
                     activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="formate--tetrahydrofolate ligase"
                     /protein_id="HFG9696242.1"
                     /translation="MGFKSDIEIAQEAKPQDIREVAKKLGLGEDDVELYGKYKAKVDY
                     NLLKRETGKKAKLILTTAINPTPAGEGKTTTTIGVADAFAKLDKNVLVALREPSLGPV
                     FGVKGGAAGGGYAQVVPMEDINLHFTGDFHAIGAANNLLAAMLDNHIHQGNALRIDPK
                     KITWRRCVDMNDRQLRNIVDGMGKKGDGAVRQDGFDITVASEIMAAFCLASDISDLKE
                     RLGNIIVGYSYEGEPVTARQLKANGAMAALLKDALKPNLVQTLEGTPSFVHGGPFANI
                     AHGCNSVIATRMAMHFADYVITEAGFGADLGAEKFLDIKCRMANLKPDAVIIVATVRA
                     LKYNGGVAKADLNNENLEALEKGLPNLLKHVENITQVYGLPAVVAINRFPLDTEAELK
                     LVEDKCKELGVNVALSEVWAKGGEGGIAVAKEVLRLLDEEENNFRFCYEDDLSIKDKI
                     NAIATKIYGADGVDYTPEADKEIANLEKLGFTKVPVCMAKTQYSLTDDQTKLGRPTGF
                     RITVRQATISAGAGFIVALTGEIMKMPGLPKVPAAEKIDVDENGVIAGLF"
     gene            complement(46626..47405)
                     /locus_tag="ACGI5H_000513"
     CDS             complement(46626..47405)
                     /locus_tag="ACGI5H_000513"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888532.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HFG9696243.1"
                     /translation="MKIAITGKGGVGKTTFSSMLSRMFAEDGYRVVAVDADPDANLAL
                     ALGFPKEVYESIVPISEMKKLVSDRTAASVGSFGKMFKMNPKVDDIPENFCKEYNGVR
                     LLTLGTVDSGGTGCVCPEHVLLKRLCSHLILQNKDVVVMDMEAGIEHLGRGTAQGVDA
                     FIVVVEPGERSLQTYRKVKKLGHDIGVNKVFVVGNKIRNKEDEEFIIQNLEDGESLGF
                     IYYNQDVIDSDRANQSPYDSSETTKEQIKAIKDKLMSLKDK"
     gene            complement(47715..49634)
                     /gene="cooS"
                     /locus_tag="ACGI5H_000514"
     CDS             complement(47715..49634)
                     /gene="cooS"
                     /locus_tag="ACGI5H_000514"
                     /EC_number="1.2.7.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860935.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016151 - nickel cation binding [Evidence
                     IEA];
                     GO_function: GO:0043885 - anaerobic carbon-monoxide
                     dehydrogenase activity [Evidence IEA];
                     GO_function: GO:0051539 - 4 iron, 4 sulfur cluster binding
                     [Evidence IEA];
                     GO_process: GO:0006091 - generation of precursor
                     metabolites and energy [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="anaerobic carbon-monoxide dehydrogenase
                     catalytic subunit"
                     /protein_id="HFG9696244.1"
                     /translation="MDEKMLTIDLNSQKMIAKAREEGVETMYDRKEGFKAQCGFGLQG
                     VCCRICGMGPCRISPKTPRGLCGADEHTIVGRNFARMVAGGTAAHSDHARDIAHTLAL
                     ADPNGNYKIRDEAKLITLAKEWDVETEGRDIYDVAHEVAEIALMEFGKPFGTLRFIKN
                     APEPRQKIWKEYAIEPRAIDREIATIMHSTHIGCTGDIDSLIHMSLRTSMADGWGGSM
                     IGTRLSDILFGTPVPRRTEANLAVLEENKVNIILHGHEPALSEMIVLASEEPDLVALA
                     KEVGADGINLAGMCCTGNEITMRHGVKIAGDFHQQELAIITGAVEAVIVDVQCIFPAL
                     ARVADCYHTKFVTTSPKAKITGSTYIEFREEQALDDAKAIVKEAILNFKNRDKSKVLI
                     PELKSGATVGYSVEAVVNQLDRVVNSHIDPAGTVKPLTDCLKSGVLRGAAGVVGCNNA
                     KGVSNEAHVTIMKELIKNDIIVVTTGCGASAAAKFGLMESDAAEKYAGKGLATVCKLV
                     GIPPVLHMGSCVDISRILDLVGAAANYLDMDMCDLPVVGIAPEWMSEKAVAIGCYVVA
                     SGIDTYLGIMPPIAGSSRAVDILTSELKDKVGATFTVNTNPKELAATIIEDIEKKRVH
                     FEALVEEKMAEKAEA"
     gene            complement(50241..51152)
                     /locus_tag="ACGI5H_000515"
     CDS             complement(50241..51152)
                     /locus_tag="ACGI5H_000515"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436909.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016746 - acyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional enoyl-CoA hydratase/phosphate
                     acetyltransferase"
                     /protein_id="HFG9696245.1"
                     /translation="MIKKLDDILEQLKGGEKIVLSVAAAHDKEVLMAIKDAVERNIIT
                     PILVGNEGKIREISKEIGFDLSGIKIVDKDDIKECAEIAVKLVSSKEADFVMKGLLDT
                     SVILKEVLNKDYGLRTDSLLSHVMVYELEKYHKLLITTDGGMNIAPDYEQKAKILKNS
                     IKAAKALGMETVKVACLAAKEKVNPKMQATVDADMLAKACKEGEFGENVIVEGPLAFD
                     LAVSKEASEIKGFKSEVSGDVDIILVPTIEVGNGIGKAFTYMADSKSAGIIMGAKAPI
                     VLVSRADSHESKLYSIAYGAIVAKNMK"
     gene            complement(51268..51846)
                     /locus_tag="ACGI5H_000516"
     CDS             complement(51268..51846)
                     /locus_tag="ACGI5H_000516"
                     /EC_number="2.3.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902116.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016407 - acetyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sugar O-acetyltransferase"
                     /protein_id="HFG9696246.1"
                     /translation="MNINEFLTHINQRKPVSSKSEIHEFMVKLSNEAMKITSKLNSSY
                     HEPEEVRSLFSELIGKKVDESFFMFPPFYTDCGKNITIGKNVFINSSCHFQDQGGIEI
                     GDNTQIGHNVVLATLNHGIAPEKRGTTYPSPITIGKNVWIGANVTVVPGVTIGDNAII
                     AAGAVVTKNVAENTIVGGVPAKLLRVIDEIPE"
     gene            52072..52995
                     /locus_tag="ACGI5H_000517"
     CDS             52072..52995
                     /locus_tag="ACGI5H_000517"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895771.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HFG9696247.1"
                     /translation="MEIRVLRYFLAIAREESISGAATFLHITQPTLSRQIMELEEELG
                     VKLLVRGNRKITLTNEGRLLHKRAEEIISLVDKVELEFDNPNEIISGDIYIGSGETEA
                     MRLIARTAHHFHQKYPNVRYHLFSGNADDVTEKLDKGLLDFGILIEPANIQKYDYAQI
                     PATDVWGLLMRKDSALASQSTINPKDLCNIPLIISRQTLVDKAISKWLQDSNEKLNII
                     ATYNLVYNASLLVEEGLGYALCLDRLVNTTENSNLCFRPLSPPLEAKLNIIWKKHQIF
                     SKAAEKFLLQIQKDFSSIMLDTSKLDTPKEK"
     gene            complement(53167..54309)
                     /locus_tag="ACGI5H_000518"
     CDS             complement(53167..54309)
                     /locus_tag="ACGI5H_000518"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418311.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetratricopeptide repeat protein"
                     /protein_id="HFG9696248.1"
                     /translation="MDFKIEKYLLKKAEELAFITIKHGGEFKLKSYEVPKGGLDVPIK
                     NEVLVKGIKEKTAQDKLNSMSIADAMIYIIGIDSKFKNNAEYEKFLNALSKDIDLDLK
                     SYMGYMSRKYFEIGEHTDSLIYIKAFITMYPDDLDAMYNYAIVCQEIAKQYQKDMDDK
                     AMNAFLLEAMAKLEKVIDVDENFALGYYHLGYHYYNQGQYLKTKLTWEEALRLGLDAD
                     LVAEVQENLGKMDFKVQYEEGYTLVFQGKFKEGLEKLLPLEEEHMDWWNLLFMIALGY
                     KGMGEIEQAKMYLEKILIIKPNQVDTIVELGLCEAYKNNLDKAIEYFEQAAKIKEDPE
                     ILCNLGMAYLNNGDIDDATYYIERAYELNPQDEITIACLRELRINK"
     gene            complement(54327..56081)
                     /locus_tag="ACGI5H_000519"
     CDS             complement(54327..56081)
                     /locus_tag="ACGI5H_000519"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="B12-binding domain-containing radical SAM
                     protein"
                     /protein_id="HFG9696249.1"
                     /translation="MKILLTTLNSKFIHTNLAIRYLKEFVRDLIEVNMKEYTINNDLD
                     YILKDIYKNEYDIILFSTYIWNVGDIVKLCDNLKKIRPNTKIALGGPEVSYDSYEAMK
                     KYDFVDYILYGEGELIFRDLVLHLQGKMEINDVNGLVYRQGNEIIVNKPMELLQDLDE
                     IPSPYENLNPKEYENRIVYYESSRGCPFNCQYCLSSTIPGLRYFSLDRIKSDLKALID
                     ARVSQIKFIDRTFNANRKVAMEIMDFLMKNDNGYTTYHFEVTAYLIDDKMLEFLADCK
                     EGLFQFEIGVQSTNEKTLDAVGRRDDFKKLSHVVQTVASYRNIHQHLDLIAGLPYEDY
                     KSFENSFNDVFNLGIEHLQLGFLKMIKGTGMRKVADEHGFKYKDYAPYEFLYNNYISY
                     EETLKLKDIEDILERYYNSKNFVLSMRYIIGRFYKKSPFKFFEVFAKYFDENGYFDLA
                     QGKNQLYKILMDFYNEKINIDNDVFNDILKYDYISLGKTSNIPQFFNKLDVDDFKNRC
                     HVFLQDNDNLSTYLPSFVDKPAKHIIKYVHFEPFRFNVVDLKNDINTEIREVENVVLF
                     EYDDKKIFEKSKTHKVEI"
     gene            56217..56423
                     /locus_tag="ACGI5H_000520"
     CDS             56217..56423
                     /locus_tag="ACGI5H_000520"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418305.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9696250.1"
                     /translation="MELIEKVSINSLSKRDLLLIIKSLEYTNENTQISDFIDLRNNIV
                     KELCFLTDTKEKDFLDYLEKNSTL"
     gene            complement(56428..57351)
                     /locus_tag="ACGI5H_000521"
     CDS             complement(56428..57351)
                     /locus_tag="ACGI5H_000521"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860932.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9696251.1"
                     /translation="MNDELLKKVYTSSFSSASRALKDLTIINTKSLIDDKTQRCVYID
                     ENRLRDELIYYRFYGEKIGNINFLNILLPLILSNTNIQKSEDEVIKLIKKYVIYFKKE
                     ELLFDYLLGSVVYNSIMHNLINNSKIEYVELLQSIKDKIIGFSIELDKSDVVKFQMAR
                     IKAIQLIDKYIDLKSEDYDEESILLNVLNVLYDVYMEDRTVENEGINSIKKSILSILG
                     EDSKLNEDNIDFIFSMSEYVVKLRKYKIGVKAYNKSIDPRSLIRLEEGNTIIDPIFNQ
                     ITVMSKTFNDNILSIKINSKSGIYILKFKKV"
     gene            complement(57605..59305)
                     /gene="argS"
                     /locus_tag="ACGI5H_000522"
     CDS             complement(57605..59305)
                     /gene="argS"
                     /locus_tag="ACGI5H_000522"
                     /EC_number="6.1.1.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003432277.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0004814 - arginine-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006420 - arginyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="arginine--tRNA ligase"
                     /protein_id="HFG9696252.1"
                     /translation="MQDFKVAISNCLKEKIEDLSKEEIEALIEVPPNKDMGDYAFPCF
                     KLAKVFRKAPNMIASELAESIEPSGEITKVIQLGGYVNFFVNKSQLAETVIKKVLDEK
                     ENYGHSDFGKDKTVIVEYSSPNIAKPFHIGHIRTTVIGNALYKIYDSQGYKTIRINHL
                     GDYGTQFGKLIVAFKKWGEKEVVESNPIPELLKLYVRFHDEAEQHPEMEDEARAWFNK
                     LENGDEEAQELWQWFRNESLKEFNRVYKLLDIEFDSLAGESFYSDKMNRVIELLEEKN
                     LLKESKGARIVDLEEYKMPPALITKNDGSTLYMTRDLAAAIYRKETYDFDKCIYVVGS
                     QQNLHFQQWFKVIELMGYDWAKDLIHVGFGMVALEEGTMSTRKGRVVFLEDALNQAID
                     KTKEIILAKNPNAKNVDEISKQVGVGAVVFQELSNSRIKDYTFSWERTLSFDGETGPY
                     VQYTHARCCAVLRKAEVEVTSDIDYSLLADEDSAEVLRVIESFNKNILLALKKNEPHI
                     VTRFMLDLAQAFNKFYHDNPILVENLEIRKARLALVLATKQTLENSLKLLGMHAPERM
                     "
     gene            complement(59767..60180)
                     /locus_tag="ACGI5H_000523"
     CDS             complement(59767..60180)
                     /locus_tag="ACGI5H_000523"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860931.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF523 domain-containing protein"
                     /protein_id="HFG9696253.1"
                     /translation="MILVSACLIGINCKYSGDNNDNEKVKEYLKGKEFTLVCPEQLGG
                     LSTPRPPAEIVDGKVITKDNKDVTENFVRGANETLKIANLYVCSEAILKEGSPSCGCN
                     LIYDGSFSGKKIPGKGITARLLEEEGIKVKSEKDL"
     gene            complement(60248..62626)
                     /locus_tag="ACGI5H_000524"
     CDS             complement(60248..62626)
                     /locus_tag="ACGI5H_000524"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860930.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004519 - endonuclease activity [Evidence
                     IEA];
                     GO_function: GO:0030983 - mismatched DNA binding [Evidence
                     IEA];
                     GO_process: GO:0006298 - mismatch repair [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease MutS2"
                     /protein_id="HFG9696254.1"
                     /translation="MNEKSLRVLEYNKIIDLLKKKASSSLGLKYIENLVPNTDFVEVK
                     SMLEETSEAQSIIIKRGSVGLEGIHDIEDKVKRAYIGASLDPGSLIMIADTLRVARRL
                     RNSLSSSDEEDFNYPIIQSLSNSLYVYKDIEDQIYNAIISEVEISDNASSTLRDIRRR
                     IAQKNQSIRSKLNSIISSTTYQKYLQDAIISLRGDRFVVPVKSEYRSQVAGIVHDQSS
                     SGATLFIEPMTIVEMNNELRQLKLGEQEEIERILSELSAMVGEVSEDLISNQEILGRL
                     DFAFSKGKLSIQMRGIEPTLNEDKYLNIKNGRHPLLDKKKVVANTIYLGRDFHTLVIT
                     GPNTGGKTVTIKTVGLFALMTQSGLHIPADYGSSMCVYDNVFADIGDEQSIEQSLSTF
                     SSHMTNIVSILQNVTADSLVIFDELGAGTDPVEGAALAIAVLEDINSVGAKCIATTHY
                     SELKNYALTKPGVENAAVEFDIETLSPTYKLLIGVPGKSNAFEISRKLGLSDYVISRA
                     KEYINTENIALEDVLQNVEKNRIKAVEDREEAERLKEEIEKLKVEYDEKLEKLVSQRD
                     KMIEKAKSEAFSIIRQAKEEVDIIIKELRSLEQERASKEKNRKIEELRKELTSSMGSL
                     QPTVKSMIVPKVSNKEIKDLKPGEEVKVITLNQNGSVVSVDKKRKEAVVQIGIMKMTL
                     PFKSLQKTRKDVSTNVTKSTRNIIRSKSGSVKNEVDLRGLNLEEAIMEVEKYLDDAYV
                     AGLESVTVIHGIGTGVLKAGLQDILRRNRHVKSQRGGQYGEGGAGVTIVKLK"
     gene            62945..64396
                     /locus_tag="ACGI5H_000525"
     CDS             62945..64396
                     /locus_tag="ACGI5H_000525"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895759.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoacyl-histidine dipeptidase"
                     /protein_id="HFG9696255.1"
                     /translation="MGNVLEGLKPESVFKNFEKISQIPRGSGNEKGISDFLLSFGKNL
                     GLETIQDESLNIIIRKPATKGYENCPGVVLQGHMDMVCEKEKNVEHDFLKDPIKLRID
                     GDMIYATGTTLGADNGIAVAMGMAILEDNTLEHPALEVLVTVNEEDGMNGADALDPSL
                     IKGQYILNMDSEEEGYLLVSCAGGKTCVVSLPVEYKEVKGDKQGLLVEVTGLLGGHSG
                     MEIVLQRANANKAIARVLSVLNVDYELASVDGGTKHNAIPREAKCVIAVNKADVESAK
                     KQINDILTAFKHEFTTSDPGMTYSVAETSVDKVLTKDCKEKVVQMSCLTPHGVQSVSL
                     DIEGLVESSTNFAIIETKESTIEFLTSVRSSVMSIRDEIADRIRLLAQALGANYDLIA
                     QYPAWEFKKGSKLEKICSETYEKLTGKVPTVMALHAGLECGLLLDKLPHAEAISIGPD
                     MFDVHTPNEHVSIPSVANVWDYVIEILKSMNQY"
     gene            complement(64600..67113)
                     /locus_tag="ACGI5H_000526"
     CDS             complement(64600..67113)
                     /locus_tag="ACGI5H_000526"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436881.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transporter substrate-binding domain-containing
                     protein"
                     /protein_id="HFG9696256.1"
                     /translation="MEDCVVNLKKLLLLIIVITSIFTSCIFSFGINAIGNDNRTIRVA
                     YPIQKGLTEIDEQGNYFGYTYEYLLEIAQYTGWNYEFVQVPGEINESITKLMKMLENG
                     EIDIMGGMLYNEPMQKIYNYAGNSYGVANTVLQALYENTDIDNIMSSQDVKKIRIAVI
                     ENSDTRLKELDEYCKMNLMSPELVYCKTNDEQLEALKSGKADVLLNVSMNPLEGVRTV
                     AKFSSKPFYFITPKGSTNLTQKLNSAINNIEQKDPYFSTTLYEKYFTPENNQMFLSDE
                     ETDYIKETEKLKVGVLLNKPPFQNIDKDTGELRGISIDLLNHICDKTGLEFELVPVKS
                     QEDLENMTKKREIDIVAGMIYDYEYSREHNIVMSRPFLSTQYTMMINNKLNENSLDGK
                     RVALAKGINYYGQFEENIVWYDNLEECIEAVNKGYADYTYGEGYSMQYYMNQPKYKNV
                     RLVPQTYKAKSICFGIIKKDKQELLNIFNKAIISISSEKMQSIVYQNTTYRQDFSLLY
                     IMQQNPIETIFIVASLLICIIGFMAFGLHTRTSMNEKISLELKKHTQLYEMTSEYFFE
                     YDYKQDKLIISMPEKGIETYYGLDKNDKESENGNIENERDKIRKEYNKKFFDVIKSQE
                     NGTTEMYSIMLDDTFHWIRVTSKIIYNDRKIPMYVIGKICNIDSEKEEKNRLLDKAQR
                     DSLTNIYNAAYIRKLTAQNLLNLSTEKNGALLIIDIDYFKSINDTYGHLLGDKVLIDV
                     AKVLDESFAKNDIVGRLGGDEFSVYINDIINKEELINKCNDVYNHIHLIKLPNGESLS
                     ISMGVVIAKPGQEYDELYQIADNALYDSKRQGRNRFKIV"
     gene            complement(67336..68157)
                     /locus_tag="ACGI5H_000527"
     CDS             complement(67336..68157)
                     /locus_tag="ACGI5H_000527"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436880.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nitroreductase family protein"
                     /protein_id="HFG9696257.1"
                     /translation="MIDINLEKCVGCGMCESDCLVNAIKVKDDKAKVKNILCINCGHC
                     MAICPTDAIEMQGFDKNEVIEYNRESFELEPEKLLNFIKFRRSIRQYKDIEVEEEKIK
                     NIVEAGRYTPTGGNRQPIRYILVKEKLKEVKELAIQGLYNLALDTDDNDPVRSIYKNT
                     FKKMYKRYKENGNDSLFYDAPLLMVVVGDMSLGGSAYVDGGLAASNMELMAYSQGLGI
                     CYNGFFVMASNVEPKIKELLGMSENEAVITSFILGYPDVKYKRTVNRNTAKFEVR"
     gene            complement(68675..69151)
                     /locus_tag="ACGI5H_000528"
     CDS             complement(68675..69151)
                     /locus_tag="ACGI5H_000528"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888511.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX domain-containing protein"
                     /protein_id="HFG9696258.1"
                     /translation="MKLTTICYIEKDDKTLMLYRNKKKDDIHEGKYVGVGGKFEQGET
                     PEECVIREVKEETGLTLKSLSYKGLITFPKFKDEEDWYMFLYFSDEFEGELSEKDLND
                     CKEGNLIWVDNDKIFDLNMWEGDRLFLNWAKTGNIFSAKIVYDNGKLKDYNVSFLD"
     gene            complement(69185..69763)
                     /locus_tag="ACGI5H_000529"
     CDS             complement(69185..69763)
                     /locus_tag="ACGI5H_000529"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418276.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HD domain-containing protein"
                     /protein_id="HFG9696259.1"
                     /translation="MREEALEILFKYLETDRMRKHCYAVEAVMRELAKRLEPEKEEEW
                     AVAGLLHDLDSDIVGRKPGEICEGHATTTVELLKKENFGDEEMYRAILGHHDGMGVTR
                     TSLMEKAIYAADPITGFITAIALVYPDKKLTSVKTKSVIKRMKETRFASNVNRDAMRS
                     IEDIGIPFDEFAELSLNAMKNISDVLESAENN"
     gene            complement(69867..72449)
                     /locus_tag="ACGI5H_000530"
     CDS             complement(69867..72449)
                     /locus_tag="ACGI5H_000530"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895753.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="U32 family peptidase"
                     /protein_id="HFG9696260.1"
                     /translation="MKKIELLAPVGSFDSLKAAVQNGANAVYLGGKDFSARASANNFD
                     RNELIEAVKYSHIRGVQVFVTVNTLIKQYEIEDFVEYVKFLYDIDIDALIVQDIGMAR
                     LIKKLLPDFELHASTQMVAHSLEDVKYLQSVGFDRVVLARELNVDEIKWICENTTVDI
                     EVFVHGALCVCYSGQCLMSSMIGNRSGNRGRCAQPCRQKYELIDINTGEVVKSNGDYL
                     LSPRDLSTIEDLDKIIEAGVLSLKIEGRMKKPEYVATVVSGYREAINEFVDKKKISIS
                     EEIINNLYTIFNRKFTKGYILGEVGKDIMNSNRPNNQGLYIGKVLDYNRKNKRLRVML
                     ENTLKKGDGINLGGGTIGRIIKDGEITTIAHKGDLIELDFVGEAKRNQLIYKTSDSEL
                     MDRVQATFQQDKEFIKTNIRAKVSIKLGKKPELFISDFCGNKSVVEGDKIVEKAIKVA
                     LSKEKIETQIQKLGNTPYKLKEIEIDLDEGVSMPISVLNQMRRDCIELLDEERIKIKD
                     RKFKKNRLKYQPNRVNKQKKLDTVPKIRVKVKNLEQLEAVLNYNVDLIYYEDINTLSK
                     ALQMVSSISIDSSISMDLYTSSSLGIPKELMGSNTNNIYTLSNTSKIDTLNKNHSNTA
                     VTDKKLIYSAPRIVRNKEYKQFEILDNIKGINKVQIGNWGSMEYFKKKDLNIDCYLNA
                     FNSESINHFKEEGASTVCLSQELNLNEIKQTLKYTDVEIEAVIYGYAPMMVTEYCPMG
                     VVVRDCKKDKRVAKCKESSYALRDFTDASYRITQDIFCRSTIYNSKVTCMLDNLYELE
                     EIGIDVFRIDFTVEDSEMVKKVIEAHIEVLSNNYKLGKRATDLYKKLDEIGTVAGHYY
                     KGVE"
     gene            complement(73019..73702)
                     /locus_tag="ACGI5H_000531"
     CDS             complement(73019..73702)
                     /locus_tag="ACGI5H_000531"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003432289.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="YoaK family protein"
                     /protein_id="HFG9696261.1"
                     /translation="MTSKSQMSESFFLCSLLAITGGFLDIYTYVVRGKVFANAQTGNI
                     VLFGLNIAEGNVKESFYYLIPILAFMLGVFIAEKIRKYFTNNKTKIHWRQVIIIIEMI
                     TILIVSFIPRGRFNMFVNVAISFICSMQVESFRKVNGNSFATTMCTGNLRSATETLFH
                     YIHTKNIFMIKKSLQYYAIIIFFISGAILGTFFTKIFVEKSILICFFILAVVFGIMFI
                     NKDDSFNEN"
BASE COUNT        23080 a        13773 c         7989 g        29026 t
ORIGIN      
        1 aaatttagat atttttctaa aaattatcta tgttaatagt taaatttatg aacatttttt
       61 gtttttatgt taggatattt cttagaaatg aaatacttct taatttgatt tgatatgtat
      121 atttttatag ctattttatt ataaaaaaaa agaacccttt tataactaag ggttactttt
      181 tttctctatt ttttcttatt atatcactat tttttcccta tttcaatatt ttgacatttt
      241 ttccattata ctgaaaagat atcttaaatt tttaacttgg ataaatttta aagcatatac
      301 ttaaaattaa catacttgtt ttctatttta ttacacttaa tccttatttt tatcattcta
      361 caaaacaaaa ataaaaaaga ataagataat aaataaaata cttatcacct tattctttat
      421 ttaattattt tacaacgaaa aatctaaact actttttaaa tagcttcctc ttccatcaat
      481 ttatttgtat attactgatt taattcttca agtaactgat tggttcttgc aatactttat
      541 cctaaactct ggaaactttg taaactacct ctctagcatt tggtaaattt ccatctggaa
      601 tacctacagc aataccaaat ggtacagaat acccttctgg tatatcaagt agttctctgt
      661 attttttatt tgtatcaaac ttcatcttta ttgactctga ttcttttaca tcttctttat
      721 ccaatacact cacaagacct tcaatatccc cttgttcaac aggtgtaaat aaacctctaa
      781 ccattcctat tatacaactt ccaagcccta gtgcttgtgc agctgttgtt atattccctg
      841 taagtattcc tatatcatat ggagcccatg aactactttc atcataagaa ataaataaaa
      901 cggttggagc accataaaat aacttaaagt ttttatttat ctcaacatta ctcacctcat
      961 gaatcctaga taaagtatca tcactaatct cttttaaaag tttctggtct tgcacaacag
     1021 ttatgtgcca aggctgttta ttacatcctg aaggtgctgc aaatgcacag tgtaataatg
     1081 tgtttacttg ctcatcacta atttgttctg tcgtaaattt tcgtatactt ctacgacttt
     1141 gtattaaatt tattgtttgg ttgtcttgaa aattattatt catatctatt ccccttttta
     1201 tgtatttctt agtacaaata ctaaatcttc agaaaattaa tcttataatt aaatttcttt
     1261 acaatattat tataattatt tttagcttgt atgtgaagac ttaaaaatat aaacactttt
     1321 aatatatctc aattatatat ataaatgaaa atctggtatt cgtcatctat agaaactgct
     1381 cttttctata gtttaatcaa taccagatta ataaaacatg atatattaat ttaaaggacc
     1441 ccatccctct ttagaatgaa tctctgtttt tacagactta acactatctg tgtcaacatc
     1501 ccatgaccta cctgcaacag aaataccatt tttaccttta taccatctac cttcatcata
     1561 atcgtaaact agggaagtat accaattacc cccagtctta ttatttgcaa atacaactac
     1621 agtagcatca gatttagtag gattatatgc atatggttgt atatatagtg tatccttact
     1681 taatccatat tttgccttaa attcatctgg aattgtaggc cacccatttt tatatttatt
     1741 gtctaataaa tattttctaa aatcatcatt accctttgag gctcctggta ttatagaagg
     1801 gtcttgtgca aatgatgcaa tcaaatcttt catactttga tgtatatccc tagccatttc
     1861 aacaccatct ggatgttttg tacaagtaac atacactttt gcaatgcttt ctattccagt
     1921 tattccatca taaccatcat caaacgttgc tgaatatatt ccacctgact tacactttgg
     1981 ttctgtttca aagtacttac catctttgtt ttctaatacc tctttcatga cttcattctt
     2041 gcctttactt gattcctcag ccattgcaat aacaatttga gtctttatat tttctctatt
     2101 agaaagacat gtaactgctt tacttttttc tatatttcta aacaatgctg gaacagctac
     2161 tataactaaa atgcctatta tagatataac tactaacaat tcaattagtg taaaaccctt
     2221 tttattcata ataatcattc ccattaaata aaattatagt acttattttt aaatactaca
     2281 tattaataaa ttgtctacat aaatcctttc aacagaacta ctaatatact tacagaacta
     2341 ctaatatact caatattcaa tttagtaatt aaataacttg tatgctaaaa ctcaatatcc
     2401 tctacctcta ttttgtcaat agcatcctgt actaattttt caatgtcaag tgctgtttca
     2461 gatttttcta ttttctctaa tctaggttta gtgacgggct ttctaggaga aaatacacta
     2521 caacaatctt cttcaggcac tatagatgtt tcaaaagtcc ctattttttt ggctatatca
     2581 actatatctg atttatccat tgctataagt ggtctaaaca ctggtaagtc tacaacggca
     2641 ttagtacaag taagtccttg tatagtttga gatgcaacct gcccaatact ttcacctgta
     2701 attaaagcat cacaatgtct tttttcagaa agtctctgcg ctatcctcat cataaatctt
     2761 cttgaaagaa tagtagattc ttcttcatta caattctcgc caattgcttt ttgtatttct
     2821 aagatattaa ctttatgaag ccttactcta ccacagtatt ttgccagtat tttagctaaa
     2881 tccttaactt tttcctgtga cctttcactt gtaaatggat aactatgaaa gtgaactgcc
     2941 tctacttcca tacctctttt tgcaaccatc catgtagcta ctgggctatc tatacctcct
     3001 gataaaagag acatagctct accattcgtt ccaagtggca atccaccata tccaggtata
     3061 gtatcactat agaccatagt atgaaattct ctgtattcgc actttatttt aacttctgga
     3121 tttcttacat caacattaat cctatctcct acctttgata ataagtatcc acctatatcc
     3181 atactcattt cttgagaagt caatccgaaa gacttatctc ctcttcttga ctctacctta
     3241 aaagttttat atccagcctc tattttttct tctaacattt ttaaagctat ttcttttaat
     3301 gtatcataat cttttttagc tcttactcca gggcacacac ccactatccc aaatactttt
     3361 ctaacttctt caattacttc ttcataatca tagtcttcta aatcaacata tattcttcca
     3421 tactctttat atacattaaa tcttccaatt ggttttaaca tatttcttat atttcttata
     3481 agcctattct caaatatata tctattcttt ccttttactc caatttctcc atactttact
     3541 attaatatat tatacaccat ttcacctctt aaactaattt attatcacta tttatacagt
     3601 attctttatt ttcttttcat tattgacctt aagtcacaaa ttgattcttt caaaactttc
     3661 acagcttcta acatttcttc ttctgtattc atatcagata aactaaatct tattgttcca
     3721 tttatttctt catttgtaag acctatagca tttaatacgt aactaccttt ctttttagaa
     3781 gaacatgcag agccagttga tacataaata cctttttgct ctaagtaatg aagtaaaact
     3841 tctccttttg tccctctaaa tgatacattt aatatatgac atactccgtc ttctggagaa
     3901 ttgattttta tatcttctat attatcaatt atttcatttt ttaatatatt ttttaagtta
     3961 tctactttcg aaataacagc atctaaatct ttgtttagta ttctaacagc ttctccaaga
     4021 ccatatattc caggtacatt ttctgttccc gacctaattc caatttcctg accaccacct
     4081 gttaacatag gcttaaggcg attattttct tttatataca taaatccaat tccctttgga
     4141 ccatgaaatt tatgtgcact tacactcata aaatctatat tgtatttaga tggtctaaag
     4201 ttaatttttc catatgactg aatagcatca acatggaaat aaattttttc ttttaaaccc
     4261 ttcaaatact ttccaacttc acctattggc tgtatagttc ctatttcatt gttaacatgc
     4321 atcatgctta ctaagcatgt agttgacttt atcgcatttt ttaaatcctc tatatttatt
     4381 ttcccatctt ttccgacctc taaataagtt acttcaaaac catcttcttc taaatctttt
     4441 aatgtattta aaacagaagg atgttctatg ttagtagata ttatgtgatt ttttcttttt
     4501 ttatttaaac tagtaatacc tcttattata gtattattac actctgtacc acctgatgta
     4561 aaataaatct ccttttcttt cgctcctaga gatttagcta tatcttgtct tacttctttt
     4621 atagcttttt caacttctac accttttcta tggacagaag aaggatttcc atattccgta
     4681 ttaagtgcat aaaccatttt atctataact tcttgataag gttttgtagt tgcgctattg
     4741 tctaagtata tttccaactt aattacacct acctttattt aaaatcttca actctaacta
     4801 ttataccact aattatagta ttttttttgt taatctttat taaaaagaca atcttaaatt
     4861 ataaaatatt atttcatgaa aagctagttt tttcacttta ttacaaattt ttatagtaaa
     4921 atataatata cttatactat accctacaaa aatatattat aaaatacaat atatgataaa
     4981 ataatatatt atataaaata aatatattat attatacata tacttatttt tactataaaa
     5041 gttaaattta taagcttact tgttataaaa ataactttta taatttattt caaaaaaaat
     5101 attgattttt gtgtcgcatt ttgttataat aaattaaggt tatccccctg gtaaccctag
     5161 ttagttaata tatctattcc caataccctt tcataaggat atattttata tttattaaaa
     5221 atcggattag taacggaaat taattcggtg gaaaaaaaga gcttaccccg agctcttttt
     5281 tttctgcaaa aaatcgtaaa aataaagtta atattaatat aactttaatt ttaaaattaa
     5341 tattaaccat cactaaaaaa ggatgtattg aatttctaat atcaataaca tcctttttat
     5401 atattatagc acttttgcta aaaatgcttt tgttctttca tgttttggat ttccgaaaac
     5461 ttcttctgga gtattatctt caagtatact tcctccatct ataaaaataa ctctatctgc
     5521 aacttcctta gcaaatccca tctcatgagt tacaattgcc attgtcatac cttctttagc
     5581 aagttctttt ataacatcca aaacttcgtt taccatttct gggtcaagag cagatgttgg
     5641 ctcatcaaac aacatcatat ctggttccat agcaagtgct ctagctattg ctattctttg
     5701 cttttgtcct ccagataatt gtgatggata tgaatctttt ttatctaaaa gaccaactct
     5761 actcaacaaa atttctgctt ttttttctgc ttcttcctta gtcatctttt ttaatttaat
     5821 tggtgctaat gttatattat ctaaaatagt cttatgtggg aataaattaa agttctgaaa
     5881 caccatacct atattttgtc taacctcatc aatattagtt tttttatcga ccaaattttt
     5941 tccttcaaat attatttctc cacctgtagg tatttctagt aaattcatac atctaagaag
     6001 tgtactttta ccagaaccac ttggacctac tataaccatt atttcgcctt tagcgatttc
     6061 taagtctata ttttttaata catttaaatc tccaaaagat ttacttaaat tttttattgt
     6121 aatcatatta tcactttcct ttttactatt ctatgttttc cctaaatgct aaacatgctc
     6181 tcatctagtt agacacagat agtttctttt ctaataatcc aactaatctt gatagagtaa
     6241 atgttataac aaagtaaatt gctgctgcta ctattaatgg ctctaatgct ctaaatgctg
     6301 cattttttac tatatcagca gtacgcatta tctcaacaac tcctattaca gatattattg
     6361 aagattcttt tacaagtgta ataaactcat ttgctaatga aggtaatata ttttttatag
     6421 cttgaggtat tattatatat ctcatagttg accaataatt taatcctaat gatctacttg
     6481 cttccatttg tccattatca actgattgta tacctgatct aagtatctct gccacgtatg
     6541 caccagagtt tactgataat gcaaatgcac tagctataaa ttcacttggt ataccaaaca
     6601 acatagggaa tcttattcct aattgaggta aaccaaacca tactatatat atctgtacta
     6661 ataatggtgt ccctcttaaa acctcaatat agattgatga tattgctctt aataccttgc
     6721 tctttgatat ttttgccata cagataatta tacctattat aaatccaaag cataatgcca
     6781 caagagaaat tgatactgtc acacctgttc cttccaaaaa agaagtccca aatctactta
     6841 aaaaactaaa atctaaactc ataatttcat ctcccacata actttcttac taatttgaag
     6901 cagcttcagt agatgcttca tttaaaaatt cttctatctt cttgccatct tgtaattctt
     6961 ttatcttttt gtttaataat tctataaaat ctttgttatt gtcagatttt ttgattgctg
     7021 ctgccatacc ttctgttaca tctttcccaa cttcagtatt tgccattttt attccatcat
     7081 attttttaac atttattaaa gaaactgctt cattagtaac aactgcatct atgtttccat
     7141 tttttaattc tgtaattaaa tcaggtattg ctttcaaaga ttttgtagtt gtcattttta
     7201 aagtgttaac tacatattct tcttggatac ttcctgcttg aactccaact ctaagtttct
     7261 ttaaatcatc ttcagttttt actttgtcta tatctgcatc tttaactata actgcatttc
     7321 tacttaaata atataattct gaaaaatcaa cactcttttc tctctctggt gttggagaca
     7381 tacctgcaag aacaatatca acttggtctg catttaaagc acctattaat ccatcaaatg
     7441 acatatcctt aatttcaacc tttacaccaa gctcttttgc aaattcttca gccaacatta
     7501 tatcgaatcc ttttattgaa tcttttccat ctactacctt atgaaattca aatggaggaa
     7561 attctgcact agtaccaaca actaattttc cattgtcttt tatttgttct aactttgttt
     7621 tttctcctcc accactacat cctactagcg ataatgtcaa tcctaatact aatcctaaac
     7681 ttaataattt tttaaatact ttcattttaa ctacccctct cttttaatta taatttccct
     7741 cagattttaa tacttaaatg tttcgagtta caaaaaaagt ctctcagtct ttaatgacta
     7801 agagacgact ttaccgcgtt accactctta ttgataaata cttatattac tttcaaaatt
     7861 tgtgactgtt agcatttaag ctgtatggat acttttattt ttaaatcaaa aaagtccctt
     7921 agctttacag ctaagagacg aattatatcc gcgttaccac tctttttgat aagtaagtac
     7981 ttatcctctc aatcccttaa ggcgggtaaa ccaattatca tactaaagtt tctgataatc
     8041 tcctccagag ctctcttcac atagacttca ttgctaggct tacaccaacc cctaactcgc
     8101 tgtaaatcca tatatgctac tttctctatc attggatttg tttccttaaa ttgttaatac
     8161 aattgtactt ccttataata tttttgtcaa taagtttttt atttttttaa taatttttac
     8221 ttgtaaatta tctaaatact actgtttata tttattgata ttagttttgt aattataaat
     8281 agtatatttc atatttttag atatttctta aataatacta aataatatct ttcacattgt
     8341 tgctttttct taaacaatac taaataatat ctttcacatt gttgcttttc ttaaattaca
     8401 ctaaataata tctttcacac tgttgctttt tctttaataa tactaaatag tatctttcac
     8461 actgttgccc tttctttaat aatactaaat aatatctttc acattgttgc tttttcttaa
     8521 attacactaa ataatatctt tcacactgtt gctttttctt taataatact aaatagtatc
     8581 tttcacactg tttctctttc tttaataata ctaaataata tctttcacat tgttgctttt
     8641 tcttaaatta cactaaataa tatctttcac attgttgctt ttctttaata atactaaata
     8701 atattttcca cattgttgct ttttctaaac aactataaat aatatattaa acccttattt
     8761 ctttttctaa taagttaaat aatacatttt acacatatct atttgtcttg cacataataa
     8821 ataatacatt atatttctat ctaaatttag attctaaatt aaatagtata aattatattc
     8881 ttcaataaac aagttttcaa atccaagatt cgctctctat ctttaaactt tattgtaaac
     8941 ataattccat cttttttaat tatttctcct tcatgaaatt ttttatggta taccttatcc
     9001 cctacaccaa tactgtcaat ttcttttttc gttggagatt ttatatcatt aataaataat
     9061 gatttatcaa ctttcttacc atacttattt aaagtagagc ttatacataa cttttcttca
     9121 gctcttgtaa tagcaacata cataagtctt ctttcttctt ctaattgttc ttcttttttc
     9181 tcttccttac aaatatcata tgatttttca tgaggtattg ttccttcatt tacacctata
     9241 atataaacat ttctaaattc taatcctttt gcactatgca tagttgtaaa tatgacaccc
     9301 tcagtctgct tattcttgtt attttccgtt aactcagtct ttactctatc aatatgctct
     9361 aaaaactctg taacagtatt aaaattagtt gctgaactct caagttcatt taatatctct
     9421 acaagtccat tagtctttat ctttctgttg ctacaataat ctaaaacata tctatcataa
     9481 tcaagactag ttctaatata agatattgca tttttaggat ttaaagtatt taaataactt
     9541 aaatctattt ccaaatcatt tattgtttta acttgtttag gatgaagatt acacttattt
     9601 attaatgctg ttataaagtc tttttcatcc ttaaccatat ttatactgtc tttggatata
     9661 tatctaaaag gcttgtttat aattctcaac caatctttat ttgattttgg attaatacct
     9721 attcttaaat aggctagtat gtcttgactt gcccaatggt catatattgt aattactgag
     9781 tcttttacta caaatggaat cctcatatcc ataaatacat ctactaatgc tcttgactgt
     9841 atattagttc tataaattac tgcaaaatct gaatactcta cataatcttt ttgtatttcg
     9901 tcaattattt ccctggcaat atataaggct tcttcctctg aatcatgcgg agaaatatag
     9961 gtaacacttc ctccatcccc ctgactacac ttaatgattt tttcatatct atttttattt
    10021 ttgtcgataa gtctatttgc agtatgaact atctcacttt tagacctgta atttatatct
    10081 aatattattt ttttagtatt attaaagtat tgttcaaatt caagcaaaaa atctggtcta
    10141 gcacctctaa atccatatat actttggtct tcatctccaa ctgcaaatat attgtttaat
    10201 gggctacaaa ttaactttaa aacttcaaac tgtactttat ttatatcttg aaattcatct
    10261 atcaatatat atttatacac atttctaacc atttctagtg cagacttatt gttcaaaagt
    10321 aaataataag ttcttataag catatcatca aaatctattt tattaacttt agatttttgt
    10381 tcttcgtata agttgtatac ttttaaaaac tcatcttttg ttaatacttc tgaattaaat
    10441 tcatttttat ccataagttc attttttaca taggaaattt catttataac ttgtcctata
    10501 ttctcatcat catcagcatt ctctatattt aaacttttta ggattgcctt gattgtcatt
    10561 cgctttgact tttcatcaaa tatactgtct aagttgtatc tttcaaagta tcttagaatt
    10621 ttaaaaaata cagagtgaaa agtaccatag gttaccttat taagtcttat gtcatcactt
    10681 aaattcaaag ctctattttt catttctatt gaagatgcct tggtaaaact tattgccaag
    10741 attcttgttg gtgctatgtt tttgtttaca accatattgg ctattctata tgtaattact
    10801 ctggtcttac ctgaaccagg ccctgcaagt atcatgcaag gcccatctat atgctcaact
    10861 gcttctaatt gattttcatt taactttctt atatctatat ttgttgtgat tattagctcc
    10921 accaccttga tttataatta tattattttc tttttaatta taaactaaaa gttcataaaa
    10981 ataaatttaa tttttcctct attaaaccac atcattccta ttttcatgac atatcttgag
    11041 ttctttttta attttgtcgc ttatatcttc aggtataaat gatggtttac taatatagta
    11101 gccttgcata taatctactc caagattaat tagtgtttcc atttcacctt ttgtttctac
    11161 accttctgct atcactttaa tatttctttc gttagaatat gagataagat tttttaatat
    11221 tttctgtctg ttttcatctt tatcaatacc tcttacaata gacatatcaa tctttacata
    11281 gtctggcatt atatataata gtacagcatc tccgttgtaa cctgtcccaa agtcatctaa
    11341 agcaatttct atattccaat ggtctatata tgctttcttt ttctcaataa aatcttcatt
    11401 aatcttatca ttctctgtta tttctagtac tactctattt aaatattcac catataaatc
    11461 ttcaatttcc tcaaaatcta cttttgacaa attattatta ggaatagaat ttaagaacag
    11521 tttgcaatcg ccaaattttt ctttgtattt tttaaatgat ttaagtgctt taaaccatgt
    11581 aatacgctca atttgatata atttagactg tgaacgagct aatctaatga catctattgg
    11641 cgaactaaaa gtttttattt taggtctcat aagtgcttca tatgcaaaaa ctttaccttt
    11701 acaatctaca ataggctgaa atgcatactc aactaattga ccatcaatta acttgtttaa
    11761 ttcttctcta ttactcaata agaatgaatc cttattatat atattaatat caaattcact
    11821 aacttcaccc ttgattgtat ttttaatttg atacatagca aaatctgcgt atctcattaa
    11881 ttcatcatag ttggttgagt catcagggta ccaggaaatt cctgctgatg cccttatttt
    11941 aaattctgtt ccatcatgaa gttttaataa ggtattattc atctgtttct taacagaatt
    12001 aataatatct cttatactat ctttactttc atatccatat ataaatacat aaaactcatc
    12061 acctgaaagt ctagatacta taccattcca tgatataaac ttcttaagta tgtctgcagc
    12121 acacctaata tattcatcac cagcatcatg tccatatgta tcattaatat attttagatt
    12181 atctaaatcc cacataataa atgctgctat cttaagttca tctttattct taaatttttc
    12241 ttgtatctgt gaatgaaaag ctctcctatt taaaagattc gttaaaatat caaaatctct
    12301 ttcatattct atcttccttt tctcaataaa ttcttttgtt acatcaacaa caacaccaag
    12361 aacctttagc tcatcttcaa agatattcat tcttatccac ttaagttttt tatctttaga
    12421 ttcaaactta tatatatatg tattttctgt ttcataactt tcttgcaaat atttatctag
    12481 tccccttaat tttttcagga acttattttt ttccatatat ccatattctt caaatttgat
    12541 ttcagtagta aacacgctaa aaaattcttt tgtacaaaaa acattctctg cgtttttgta
    12601 taactcaaaa gctccaattg gcatatctac catttcaata atctgtgata attttgacga
    12661 agaatctgca acatttgcac tgagcaactc tatagctgaa gataattcat ctatttcaga
    12721 tatatttatc ttatcaagat ttactggttt tgatggatta ctgtttctaa ctttgttggc
    12781 taaaagaaca attggttttg taaataatct tgatgcaata taaataccta ttagacctat
    12841 taataaagaa attgctatag atattataac taatttctct accctttttg aaaatgacaa
    12901 aagacttttt tcttcaataa tacccaaaag agcccaacgt tcattttcaa atggagtatt
    12961 ggagttatat aaatctaagt attgtacact agcataaatg ttgccattac cacattcatt
    13021 atctttattt ttaatcttat atatattttt atacgattcc ttctgctcta aattagaatg
    13081 taaaccatcc caaaattttt cttttaatga gtatccattt gaaattacat tttcaaaggc
    13141 catatcatta tttctatcta cacctaaaat ataattaccc tttttattcc catttatctc
    13201 tgagtatgga agtaattctc ttaaataatt tacacttaaa tctattccaa gtactccata
    13261 tacagttcca tcttcataaa taaggggaac tgtatatgtc ataagcctat cacctgcatt
    13321 tgtcaataaa aacttacttc cccagtatcc taaattagaa cttgatacat ttggattatc
    13381 aattgcagct ctaaatggtt tataaaaaaa atcatctcca tcttgctcat tttcactttt
    13441 aaatgaaaac ttaggttccc aataactgtc catagatatt ccaaaacttc ttgctatatc
    13501 tgatgaacct ctctcaatta acaaatcaga attatcattt ggattaaact tagggtctaa
    13561 atcccttata tacaatcctg tcctacttat ttcaccttta ctatctattg acttatcgtt
    13621 aatatttttg tcacttagga ttataaaagc tcctgtaaca gaattttttc tcaaaagata
    13681 tattaaatca tttgatatgc tttttataat atctttgtta atttcttcat tgttgcctac
    13741 atcctcaatt aaggcatttt tttcatttaa tacttttttt acagaggaat taattgtagc
    13801 ttccgtttca cttgtatttg accatctttg taacatttca ttttgtatat aatttttacg
    13861 attaattact ctttcattta agatgtcaaa cgaattatca tttaatttct taatagttcc
    13921 tccccataaa attgtggcac aaaataaact tgtttgaatt agcataacaa taattagggg
    13981 aaatatcatc tttttcatta ttgaattgtt ttttcttaga ttgttttcca tacccattcc
    14041 acctatacct ttgtgctcgt caacacacta actgccaatt catctatttt tttatagcat
    14101 tttcaagctc agccttaaaa ctttcaaacc aagttttaaa atttttatca ttattaaatt
    14161 gtgctactgc atccttctta gaagttccac tttttactaa ttcatttatt ttatttgaat
    14221 cttctttagc tttatcaagc attgaatatt caagtatttg tctagcttta gttccaccat
    14281 caaatgcttt attagtatat aaattacaac tgttaatctg ttcaatagat gaggctattg
    14341 aaccttcaac tttatcagac aaactcaaat tatctttctt cataacttct tttataacat
    14401 ccaaatcatt cgtttttttc tttactggta agtatccaga agcaatagag aattttatat
    14461 taggttcttt atctgtaaac cattttaaaa attctactga tgcatattct tcttctttag
    14521 tagattttgt tacagccatt cctgcacctt gttgtacagc atattttcct tctcctttaa
    14581 aacgtggtgc ttgaaaaaca gatgtttcaa tattataact ctcattatca tttagcatta
    14641 ctctatctgg aaagtatgct gctcctgaac tagaacctac aagagctaat atatcacctg
    14701 tttttgcatc atcagaacga aacttaccat aagaagcaaa atatccattt atatatggta
    14761 catagaaatt atcccatagt tttttcataa ctttttcatc aatatttagc gtaactttac
    14821 catctttaac agaaaaaatt tctactccta gttgtttact tcctataata atataatttg
    14881 ctaaagcatc tcttccaaaa aatgctttac catcattagg ctctttcgtt aaactatctg
    14941 tccattcata atattttttt gatgtctcta ctaatccttc aattgttttt atatcattta
    15001 tatttgaatt tgtagctttt gcaaatttat cccaatcagt tttatttaac atcaaaattt
    15061 cagttgattt tgcaattggg aaaagtttaa actcatcctt agaatttatt ctgccttctt
    15121 ctacatattc gtctatgtat tcatttaatt cttctttact tatgtactta tccatatcta
    15181 ctagtaaccc taatttatcc atttcatatg cagtatctga gtatgctgca aatatatttg
    15241 gtacatcttc agaaccaact tttttatttg cagaatctaa aactttctct gataaatcaa
    15301 ctacattacc ttgactgaat gcttcaacaa taattccttt ttcagcacct acagtgtcat
    15361 taaattcctt aacaagctta tcaaaagcca ttttctgctg tccattataa taatgccaaa
    15421 tttgtattga tgtcggattt tctgggtcta acttataatt atcttccttc tttaaactac
    15481 atcctgtaag taataaaaca atcattgatg tgataattaa ttttgcaaac ttacacctat
    15541 tcataaaatc tactccttca aattataaaa tttataatag cattaaaact gtaacttcac
    15601 tatttatatt aattatagaa cgtttattga tatatttaaa caggatttac aacatattta
    15661 aaagcaatta agaaacatac tattacaaat atagaaaata aagcttttac ataattttta
    15721 tttctaaatg caccaaatga caccaatcct tgttgaatag ctactgtaat tactaaaagt
    15781 atcattatta tattaagttg aaccagttta aataagtaaa gcaatgaaaa cactactaga
    15841 agtacacata atacaatact agatttatta ataatatcat caatcttatc tactttctta
    15901 gattgcttat taattttatt taatttttct ttatttaaat tctcaacttt tttattatac
    15961 ctttctcttg ttttatcttt atatttagta tttttatttt tatttcccat ttattttcca
    16021 tcctctataa attttttaat tgagcttata cattatttaa atattatata tttaagatac
    16081 catatattcc tacaaaaagg taacttacta tgtatctatt tttgattttc gcataaaaaa
    16141 gccatctcct ttagaattaa ttctgtattg agacagctaa tttaactatt tatcctttga
    16201 aacattttct acattatcat atttactatc aactaaaact atatcaactc ttctattttt
    16261 tgacctacct tcttcagatg aattttctgc tattggtcta aactcaccat atcctacagc
    16321 agataattta tctggtgcta tacctgcatt gtcaataaga agttgaacaa cattggttgc
    16381 tctcataact gataaatccc aatttgactt aaactctgaa ttttttatag acatattgtc
    16441 tgtatggcct tctactctca tgtaactatt catttcattt aacatcttac ctatttgaat
    16501 aatcttatct ctagaattat ccttcacaat agctttccct gtatcaaata gtattgtatc
    16561 tttaaggctt attactaatc ctctatcttg aactcttaat gatactgaat tagccatacc
    16621 attttcgttt aaatacttct gaatttcttc accaattttt ttaaacttag cattttgtaa
    16681 agtatctaaa tcattacttc ctggttcaac tactggttct atcttgctat taccaccttc
    16741 aataactcca gaagaaccac caaaagcaga atttagagat tgagataatt gtttatattt
    16801 ctccgcatca acattactca tagaatacat tattacaaag aaaatcataa gtaatgttat
    16861 gaggtctgaa taagttaaaa gccatcgctc attgttttct tctttttcat cttcatcata
    16921 caacataaac attccatcct tttatattat tcagctctac caccaatttc ttcaagttca
    16981 attagttctt ttgaatttaa aaatattttt aatttttctg tcattaaatt agaattatca
    17041 ccctcaagta tggataatat tgcttctatc accaaaagtc tttcacttac ttcttgttga
    17101 tttatagcct taagttttga tgctattggt aaccatatta aattggcaga accaacacca
    17161 tacaaagtag ccaagaatgc aacagaaatt tgaggtccta atgcatctgg attacttgaa
    17221 agattaccta aaatatgtac taatcccata actgtaccta ttatccccag tgtaggtgca
    17281 tatccacctg ctgaatcaaa aattgctatt ccttctttat gtcgttttga tgttatctgt
    17341 atctgtgatt ccaatatatt tcttatagta actgcatcca ctccatctac cataagttca
    17401 agcccttttc taataaaagg gtctaattca tcattctcac ttatttcttt gtcaatacta
    17461 agaagcccct ctttcctagc ctttgttgca atttctttga aatagattat attttctatg
    17521 ttattaggct ttttattttt aaaagctaat aacattatct ttatagactt tttaaacaca
    17581 gggaatggag tcgaagctcc aacagctcct atagttccac caaacacaac aagtgctgat
    17641 gaaaatacaa ataatgctcc aacatgtccc ccatcaataa caaaagcaac taccaaagat
    17701 gctatcccca ctatgaaaaa aattaaagtt gtcatctatt ccctcctttc tttagttata
    17761 catatctaat catttatgac attataaaaa gactatcttt aataaaaata gcctttaata
    17821 attggcggag aaggagggat tcgaaccctc gcaccggtta cccagcctaa tcccttagca
    17881 ggggatcctc ttgagccact tgagtacttc tccatatctc tatactaata aattatataa
    17941 taaaatcata ttttagtcaa ttgttttata aaatttgagt tattttgaat tattaaacat
    18001 ctatttttac ttttttgctt aaatgtaagt tttaaatatg gtaaaattat cttgcataac
    18061 acttataata ttatttgata aatatacata cattaacaaa tatacctaaa ctctgactta
    18121 attgtaagtt atgccaaaac taaaataata ctagtccaag gaggatattt tatgttacca
    18181 caggaaagat atgagaagat tttaagtatt ctcaaatcag ataatataat taaaataaat
    18241 gacatagttc aaatgtttga tatatcaata gaaactgcac gaagagattt agcccatatg
    18301 gagagtatcg gtcttttaaa aagagtttat ggtggtgcta taccagttat agcaagtagc
    18361 gtagaactta actatgttaa aagaaaaaaa ataaactcaa acgataaaaa acagattgct
    18421 attaaatgta gtgagtttat aaatacaaat gatactattt ttatggatac tggaactact
    18481 gtacttgaag tttcaaaaaa tttgaaagat aaaaagaatc taactgtaat aaccaactca
    18541 attttagttg caaacgaact tatgaatact aatataaaag tatatgtgct tgggggctat
    18601 cttagagaaa ctgaaggttc tttttctggt ccgcttacac tgtcagctat tgaacaattt
    18661 aatgttgata aagctatttt aggcgctgga ggtatcactc ttgaaaatgg aatctctgac
    18721 tatcacttag aagaagcact tgttagaaaa aaaatgattg aaaggtctag aaaatctata
    18781 gtagttgtcg aacctcctaa gtttggtata aattcatttg catcagtagc tcctatagaa
    18841 catatagata ctattattac ctctgctagt atagaccata atataataat agagttttct
    18901 caaaaaggaa tacctttagt catagctgat aattagctta tatgattgat ttttagttcc
    18961 ttgatgtaat aaattaaaat taaggagcca aataattatt tatttagctc catttatgtc
    19021 taaactatac tttatatttt aattatgtaa ctactttcag ttagcttatc atttttagtt
    19081 atttgattgc cattttattt aatttataag ttttagttat tcgattattt tttaattgtc
    19141 tgtcttttta atttattttt agttatttaa actcctcctt taaaataatt taaatttgac
    19201 ttaagtattg tttattctac actgcatctt tcttcatttt aatactttgt tcttcttcca
    19261 aggttaaatc ttttgtcata agtatagcaa gtgcaattgc caatactcct ccaaccaatt
    19321 ttccaattac aacaggtgta atcatctctg gaactactcc tgctgtaaat cctaaatggt
    19381 cccccaaagc tgctgtagca caaaccagcc aagcagtatt tactactttc ccctttggac
    19441 tcatatcttt catcatttta tatactggaa tactattggc taaagtaaaa actaatcctg
    19501 ctgcactagt ggcatccata cctaattttc cacccactat tgtaagtggt ttattaagaa
    19561 ctttaactaa taaatgtaat attggaaaag tacctaataa cacgattgca atacttccaa
    19621 ttacttgaat accttctctt ataggtgtca tgccttttat aagtactata cctgttattt
    19681 cttgaaatgc tgctgctccc aaacctatcg ttatcaatat agatataaat tttccaaaaa
    19741 ttaatgaccc atttatcata agagtagaat taaattttaa acctactgcc aatattactg
    19801 ccaatattac tgccaatatt atcactggta tcatatttat aattaccatt gataagttaa
    19861 atcctgctat taatcctcct ataatacctc caaagggtat tgttatcaag cctatcagta
    19921 acccttttgc aaagaatggt ctgtcttcat attctataag acctagtcct actggaattg
    19981 aaaatactaa tgtacatcca agcatggatg acacaaccaa tcctgcaagc attcctgcct
    20041 ctttattgtg tgcaagttcc atagccaatg gataccctcc catatcattc gctaaaatag
    20101 ttgcaaacat agatgggtca gctccacaga gattgaagat tggtattatt ataggaccta
    20161 gtacatctga aattactgga gctaaacaaa ctataccaac cattcctaaa gccaatggac
    20221 ccattgaatt aaacccttct tcaaaccgct cgccaagtcc aaatttattt ccaattattc
    20281 tatctaacgc tcctaaaagc actcccacag ccattatgta taatataatt ttatcaaagg
    20341 gcatttttaa ttcctcctat acatgtaaaa tactctattg taacttaatt agcacacacc
    20401 tttttggtat cgttttccca attcatagct ctttttactg cttggttcca tccaagtaat
    20461 atttcttctc ttttttgagt agtcatattt ggaatatatt ttttgcttat tgtaaattca
    20521 cttctaattt catcaatact gttccagaca ccacaagaaa gacctgccat atatcctact
    20581 ccaagtactg tcgtctcagg attttctgca atttcaattg gtatacctaa tatgtcggat
    20641 tgaaattgca ttgtaaagtt atttttagta attccaccat ctactctcaa catttttatt
    20701 tttttccctg aggctaagtt catagaatca acaacatctt tgacttgaag tgcaacagac
    20761 tcaagagtcg ctcttactat atgctctttt ttagtacttc ctgttatccc aaccattgta
    20821 cctctagcat attggtccca ataaggtgct gctatacctg caaatgctgg tacaaaatat
    20881 acacctccag tacttgatat ggaatttgcc atgtcatcag tttctgaata attttttata
    20941 actccaatgc catctctaag ccattgtatt gcagcacctg ctatatacac tccaccatca
    21001 taagcatatg taactttatc tcctattttc caagcaacag ttgtcaaaat accattacct
    21061 gctatattta gttcctcacc tatattcata tataggaaac atcctgtacc ataagtattt
    21121 ttaaccattc ctggttcaaa acatccattg ccaaataaag ctgctggttg gtctaccatt
    21181 gaagcagtaa tttttataga aaccccacaa aatgcctcct tatctgtagt tccaaaatca
    21241 ccactcgtag gcattatatc tgctaaaata cttctaggta ctcctataat gtcaagcaac
    21301 tctctatccc aatccatatc tcttatatta aaaagcattg ttcttgctgc tgtagataca
    21361 tcagttaaaa aagattttcc tcctgtcatt ttccatatta accaactatc taatgttcct
    21421 gcaagtactt ctccattttt aattttttct tttacacctt ttacattatc tattacccat
    21481 ttaatttttg tacctgagaa atatgggtct ataattaacc cagtcttatc tattatctta
    21541 ttttctaaac ctggtatatt ctttaaattt tccacataat cataagttct cctgcactgc
    21601 cacacaatag cattgtaaag tggtttacct gtatttttat cccataacat tactgtttca
    21661 ccttgattat ctataccaat tccttttata tcactttcat tgattccatt ttcaaaagcc
    21721 tgttgtaata cattattact cacagttttt gtattattcc aaatttctat agggtcatgt
    21781 tcaacatatc cagattgtgg atatatttga gtatgttcca tataatcgct aaaaacaaac
    21841 tctgattttt cgtttatcaa tactgctctt gttcctgttg ttccttggtc aattgctaat
    21901 acatatttca ctttaaatgt cctcctttat tttcagaatt aataaattct tttttatttt
    21961 ttgaatatat aatctattca agttatttat attttatatc atcatgtgga tttatgcaat
    22021 attcattaca atattttttg ttatttttaa ttatagtgat tgaaaaagta tttttattga
    22081 aatattgttg caatatttat tattttattc tataatctag ttaaaataac acataatatt
    22141 ttaatattta cacataatca gtcattcaaa aatttaaatt taacttttta aggaggcttt
    22201 acaatgaaaa aaacatatct attcagtcct ggaccagtaa tggttacaga taaagtcaga
    22261 aattcacttc ttcactatga tatatgccat agaggaaatg agtttatgga tttattcaaa
    22321 gatacacaac aaaaaatcaa taaactatat aatgcaactt ctaattacta ctcattaatt
    22381 gtatctggct ctggaacatc tgtaaatgaa tgtgtactat cttctatctt tgacaaagaa
    22441 gatgcagttc tgctagttag taatggtgtt tttggagaaa ggctagaaga aatattatct
    22501 acttataatg taaaaacata taaacctaat tttgaatggg cagaataccc ggacctagac
    22561 attttagaaa aatacataat tgaaaactct gatataaaag taattgctat ggtgttccat
    22621 gaaactagtt caggaatgat aaatccagtc cctgaactag gaaaacttgc taagaagtat
    22681 aacaaaatat tttttgtaga tgcaataagt gcctcagcag gtgaatatat tgatgtggaa
    22741 gagtttaata tagatataat aacaggtgtt ggtggcaaag ctcttggagc atttccaggt
    22801 tctgcatacc tttgtgctaa agagagtatt ttacaaaata ttaaagaaaa tcaatgtaag
    22861 aatgtgtatc ttaatcttta taaacactat aaagttgcta aatcatcttc tcaaacacca
    22921 aatacaccta atgttacttt aatatttgcc cttaatgaag ctttaactga gtttttggaa
    22981 gatgacagta aaatagaaag atacaaagaa tgttctgcta ttttaaggta tggtatggaa
    23041 gaattgggtc taacattttt acttccagat aagtatatgt ctaatacagt aacatctgta
    23101 tttctaccta aagaaatcaa tgtaaatgag tttatattag ggctagaaag ggaaagtggc
    23161 tatgttgtct atccaggaaa aggcaaattc ctagatgcta acatattcca agtagcaaat
    23221 atgggagaaa tatatccaga agattgttat aaattcttag atatcttaaa atcaaaattg
    23281 gagataaaaa aagttatata acagtttgtt tgtaaaatcc tacaatatat cagtataaat
    23341 taaatagact gattttttta aattttccta taataaatta tattttatat ttttgtataa
    23401 gggtgaacta taatatgtaa agttcacccc tatttcaaat ctttttcctt caatataatc
    23461 tttttctttt aatttatttt atatttttga cgcaatcgtt ttttattcaa tcattttata
    23521 ttcttgatac aatcattctt acacttaatt attttttgtt tttgacacaa tcgttttttg
    23581 ttgaatcatt ttatattctt gatacaatca ttcttacact taattatttt ttgtttttga
    23641 cacaatcgtt ttttattcag tcatttaata ttttcaacac aatcattctt acattctatt
    23701 attgtttgtt tttgatacaa ctgtttttat tcagtcattt aatattctca acacaattac
    23761 cttttcattc aatcaaagta atctttaagc attatttttc aagctcatca aagtaattat
    23821 atacgataac ctcacctgtc tctttatctg tagtctttat aatgccctta gctccattta
    23881 cctcttcttt tgtaaattca tcatctaaca caactttgaa tttatcttcc tttccataac
    23941 cttgttgaaa ttcatctctc aaaattgcat ttttttctgc ttttggcttc aactcaaatt
    24001 caattccaga tttcatttca tcaaaataat ttaatactac aacctcatta ttcattttat
    24061 tagttgtctt tataatccct ttagctccat ttacttcttc ttttgtaaat tcatcatcca
    24121 atgttatatt aaatttgtct tcttttccat attcctcttg aaaatccctc ttcatttcat
    24181 tgtatttagt ttcaaactct ttactcttgt ttaattccat agctgataca tttgtcaatg
    24241 atgctccaat tgccattact gttaatgcca ttactatacc acttttaaat ttttttactt
    24301 tcatatctta cctcctaaat taaatgttct caatgaaatt atataaagaa aatcctaagt
    24361 tttacagttt cattcttgta actaaaatta ctattatgta accaaacttt ttgcttcaac
    24421 tattccttaa aagttgcttt tttgaggaat agttgaagtt aaataattag attttatcta
    24481 tatttataga tttaaaatca aatttatcca tataaataaa tacttatttt tgcaaaataa
    24541 aaatttttaa ttactccaat ccttcttatt tacttaaaat cctatgataa gaaatttaaa
    24601 agtctttacc ttctttaaca ataatttatt tacttttaac atacaaaata tagagagtat
    24661 atcaaaacta ttttactgaa tattctaaaa ataagtaccc cctattagta tatatattta
    24721 catattaaaa aaaagtttta aataaagtta tattttttac aacagttttg taattaaaaa
    24781 catattgaag gtaaatttaa aggtactata tactataaat atgtcgacac aataaattta
    24841 aaaaggagaa ctaaatatga aaaaaagatt aataataatg atattgtctg ttgtcttagt
    24901 actatcaagt atacttacga tatttgcata ttcaaatatt aaatataata ataacaaatt
    24961 gatatattct aatatgatag ataaaaaaac tcaaaatagt gtaaaggaaa tcctaaaaga
    25021 aaataaaatt aatgaaaaag acatagatac atttattaaa tcagtcaaca attataataa
    25081 attgcaagtt aaaatacttc aaaataatat aaatatatct aaatctggat attcttcaat
    25141 caatgcaaaa caagttccat ataacctaga aaaattgcaa gataattggg tgaaaaaatt
    25201 ccctgattat atggatgtaa attgtagaat aactgctttt agacttttta aagattttat
    25261 aaattcaaat aagaaattta ctggagactc tattgatttg aatgtcgact tggacactat
    25321 aatgaataat aaagatgcta aatttagcac caaagatgta gaaaaattta tcaacttctt
    25381 ttctgcaata ccagctaaag atacagatga tacaatcaaa attgcagaac aaataaaaaa
    25441 tgaatggaaa aaaagaaaaa tatcttttaa aaataataaa aatatatcta ttataaatgg
    25501 atttcttcgt tatccagaaa ctaaaaatgt atttataggt catacaggca tatgtattaa
    25561 aactaaaaat ggcattctat ttttagaaaa atacggtgtt acatcacctt atcaagttac
    25621 taaatttaaa aataaagaag atgtaaaaaa ttatatgttt aatagattga agatgtcaga
    25681 aggtgaaatt gaattacctg accctataat aatggaaaac gataaactta tgaaataata
    25741 actttaaacg caaaatagta tttataatta ctaagtcaat ataatagaga aggtctatag
    25801 atttgtgtaa atacaagctt atctacaatc ttatataaga atgtttatat aaataagata
    25861 gattaattct aagtcctatt attctattga attttattat tattttattt agattctatt
    25921 gttattttac ttagaactta ttattatttt gtttaagttc tattactatt ttcaatcata
    25981 taaatttaca aaagactgta cataaattta ttttatacaa acttatctac agtcttttgt
    26041 gtgaatatat ctaaataata tcgtatttat ttatttcctc tgcacagtga gaatcagaac
    26101 ctaaaactaa tggaatatcg tattttttta ccaagtctaa taagtatcca tctatataag
    26161 gctctttgca gtactctttt ctatttccag aaacattata atcaagttca taaccttttt
    26221 ctttaattaa ctttattaac tcttcaagaa ttttatttcc tttataatcg tatggaaata
    26281 cctgattaaa ctttctaact aaatttaaat gacctattct ttttggttta tgtataccta
    26341 aatctgaatt tacagctttt atcaatgttt cataatactt attataaaca gcttcaatac
    26401 ttcctaattt gtcgattaaa ttttgaaact cctctacact gtaatctaca caataataat
    26461 catcatcaat cttaattata tgtactgata aaagagaatc ctctaattcc tttccatatt
    26521 tatttaaatt ctcctttatc ccttcttcgt atccttctat aaaatccact tccgacccaa
    26581 catttatctt gattttaccc tcatactttt ctttcaactt cttgacatca ttaaaatact
    26641 ttggtaaatc ttcaatactc atacaactat cattttcagg agcagggtct ctaaatccat
    26701 ttgcatacgg aaaatgttct gtaaatgtca tttctgttat tccaacatcc attgctcttt
    26761 gtacatattt ttcaaaatca tccttacttc catgaggaca ataaggtgaa tgtatatgac
    26821 catctttcat aaataattca ctcctttttt aaagaaaaaa tctaatataa atgcataaat
    26881 cttttaactt caaaataata tttttaatca tgctaatttt tattatatct aatattagag
    26941 taattttaaa ctgcctttta agtatcttat cattagtact attttcaact taacattaat
    27001 attatttttt aacttaacat taatactatc tttaaatagt aatactcaat atataattac
    27061 ttaacataaa ataactcaaa ttgcttgatg aggcttttgc agtatttaaa gaatatataa
    27121 ttatttaaca ttaaataatc caatcttgta ataaaattta ctcattaaag tatattacag
    27181 aaaatacctc aaaataaact ttttagttca tgatatactc ttttttgcat gaaattagat
    27241 atatttttat catttcaaca atgaaaggga ggcttatatc catctttaga caacccctta
    27301 gataaaattt ttaataatta aacatcacaa aatataaaaa tcgcttatat caaacgtata
    27361 agcgattaat tatatttaca tatgtttttt agcctctaac aacattttat tagcttcttc
    27421 catatactct atagcctttt caatactctt tgctgtttct tcttttccaa tagctctagc
    27481 cttttcaacc cactctctaa atccttcttc atgagtttca ttgtgattta tccaatgtac
    27541 taaaagtatt tttaaagttt tttcatcctt agactctgat gattcctcat gactatgttc
    27601 gtggtcgtgg tcgtgagcat ggtcatgtgg atgttcatga catatatctc catgagtatg
    27661 ttcgtggcag tggtcatggt catgatgtcc atgatgatat cttacaatct ctttatcaaa
    27721 aatcattagt tattccccct gttattttat attaaactct ttttttataa ggtttacaga
    27781 atcttttaca agtagtgcta atggtttacc ttctaatcca actaactcca cattttctgg
    27841 cataataggt aaaagtatct taagtgcctc actgtctgca atagcttcac ttatattaca
    27901 agtaacttct cccatcatag aattaggtat tattacagaa ataggtgcaa ctattatatt
    27961 tgctttttta gctgatacta ctatagcatt ttcccctgta gctcctttat tagcatgagc
    28021 tttcatcata gaactagttg ctatagaatt agtccctagt gcataaattt ctacatatgt
    28081 aggtaactct tctctcaaag aagaaactat ctgggctcca atacctccac ccattccatc
    28141 tatcactgct attatcatat gaaattcccc tattaattaa ttttcttgta ttattatctt
    28201 atggtccatc aatcttattt ctttaattat cccatctatt atcttttgct ctcctaataa
    28261 atccgttaaa taaatctttc catcacaagg gtctatatta accacatttt ccataacctt
    28321 ttctaactca ttattacttt tacaaatgaa agctgatgat tcacacatat aaatctcctc
    28381 ctaatatgat ttttattaaa aatcaaaaaa agattccctt aggtatttca atacaccaaa
    28441 gaaaccttca tgatttcagt ttttgtatat tattatacct taagtatatc actttaattt
    28501 atgtaaagtc aattaaagtt aacgcttttt attatactct tcattcttgt atttttcata
    28561 tagttcttta actaattgct tctcataatc agtcaaatcg ccctccacaa actcaacatt
    28621 aaattgttca gctaatccct ttactatgtt tttctgtaga atatctatgt ctatttttct
    28681 gccaatttca ttttctattc cacttgcttt tttagctgta aatttcatag ctctttcttt
    28741 caattctggt gtcttagttt ttattaattt aaacaatttt tctacatcaa aatccagtat
    28801 tattgaacca tgttgtaata aaacaccatc ttttctactt tgagcacttc caattacctt
    28861 cttattatta atagtaactt catatgatgc atgtgcatta aaacatgcag ctgataaatt
    28921 ttccctactt attctctcgc ctctatttaa attatctgtt tctataccac ttagattcaa
    28981 ccctttaact agaccttcac ttatatatct ataagatagg ttgatgctct tatcgattaa
    29041 aggattatct tctcctataa ttatactata ggttagctca ttatcatgta atacagctct
    29101 tccacctgta attcttctag tatagtctat attcatacat ctacacttat ctaaatctat
    29161 ctcatcttcc aatttctgaa aatatcctat actcaaacaa gctggttccc atgtataaaa
    29221 tctaagagtt ggcttattat gtcctttctt atatgcagta aatatagctt cgtcaattgc
    29281 catattcatt gctccttcat atgatttatt atgtataact ctccactgat tcatgattat
    29341 tacgcctcca tttttagtat aaatatatcc tagaaatcct ctatagattt atttctctta
    29401 ttgctaaatc tatctcactt tgatttaaag gtcttgaata gttgtatata gtacttcctg
    29461 gtctttcatt atagtatggt ctattacaat ccttacaacc tcttatttca aaaggatagc
    29521 ctttgtttat gtcttttaaa atatcattgt caagctttat actatttaag tatccatttt
    29581 taaacttaaa atactctttt ggataacctt tatttatcat ataagacatt aactgtaccc
    29641 ttctataact ttctatgctt ggttgattta tcttttccat tttagttcct ctaactggag
    29701 taaatgcaaa taaactaatc gttacatcat tttcctttaa ataagtatat aaattgtata
    29761 tatcttcatg actttcaccc ataccaacta ttatatgtgt acttatttta ttgggatatg
    29821 attttgacat ttcagttata aattttaact tttcatcata gttatttcct tttatttttt
    29881 catatagttc tttatttgct gcatctattg ctattcctat tttatcaact cctgctgaaa
    29941 aaaacttctt tatctgttca tcattttcta attttgcaga tagtgaaatt ggcatgtcta
    30001 tcttaccact tatatagttt ataaagtcta aaacagagtt atgtgcttct tcacttgcca
    30061 ttgattgaat acatattctc tttatatttt ttcctttata agcttttaaa gcatctaata
    30121 tttcttcttt tgaaaactct ggccaaatta ctcttgataa tttatctttt ctagtactac
    30181 tttctattga ttgagaacaa aaactgcatt tatttatgca tttttctcca atcattatat
    30241 atgctgtggt aggaggtata tcgctttttt tgtttaatat cccaagttct attgctgtcc
    30301 caactgatag tctaatcata aaacgcaaca ctccttacac tcatttattg tcatattcat
    30361 ttctatagcc ttattctttg cagaccttga tggtaatact attctattga ctccacacat
    30421 tatagataat tggtctagct cttttctata cactcctctt ggtctcatac aacctagatt
    30481 aatttcagta tctggtaaat taattctagc ttcacataaa atatctgcta ccccttctaa
    30541 ctcaggaggt tctacatttt catactcagt cccttttgtt ggaataagga ctataaatgt
    30601 aagcttatta ggaggatttt tttgtaggta ttctataatt tcatattcac cctttatttg
    30661 tcctcctttt aaaccaatac atatatgtgg tgctacttct gtatgttctt gtattgtatt
    30721 atagacttca atataatctt ctttactctt tttcatctta taaacttctc ttattgtctc
    30781 atcatcaaac actaaatcaa aagaaactat atctaaatac ttacacaact ctacaatgct
    30841 atctttatcc ataagaccta aatgagcatt caatctatat ccttgctctt ttaagttttt
    30901 aatggtatta atatgagtat ttatagggac atctccctca taactacaac cgccactcaa
    30961 tagaaagcta gttatattcc ttgattgtac tttttcctca tattcttcta ttggcaccat
    31021 attgtttaag tagtgaccgt tgcaatgggc acatttcaaa ctacattgat tgcttgtagt
    31081 actaagagct agtgtctggt taggataagc aaactctatt ttatttccaa aattctttaa
    31141 tttaatatca aatgctattt tcattttttc agatagattc ttattcatag tttattcctt
    31201 cttaagtaca ttttactctt ctagtaattt ctttgctgtt gggaactgct ctatattcgt
    31261 atgtggtaag aaacatgcag aaataaattc atccatataa cttggatata cactaagttc
    31321 aacataagtt atttgattac ctatttcttc aagtttattt tttgcatctt tacttataag
    31381 cgctaagtaa gaaccaacaa gtgaactatt ccctatataa gtaaattttt ctctatcaat
    31441 atcaggaagt aaccctataa ttattgagtt ttctatgtct aggttgtttc ctataccacc
    31501 tgctatataa accctatcta atatactaaa atccatacct aaactatcta caagagtgta
    31561 tgcgcctgaa tatatagctc ctttagctct gatgaaatta tctatatcaa cttcattgac
    31621 tactatatca ttttctaaat caaattcttc tttaaatgct aatacatact ctcctatctc
    31681 atgctcatta aatctaactc tcttattatc taaatccctg tatattttac ctcttctatc
    31741 tattacacct ttagtaatca tttgacagat taaatcaatt ataccagaac cacatatacc
    31801 aactggtgca cattcatcaa taatctttaa tgttggctct aaagtatctt tatcaataat
    31861 tactttctct attgctcctg ctgatgctct cattccacag cttatccctc caccttcaaa
    31921 agcaggtcct gctgaacatg cacagctcat catataatct ttatttccaa atacaatctc
    31981 tccattagtt cctaaatcta taaataaaac attttcttca cttgaccata tccctgctga
    32041 taatacacct gctgttatat ctcctcctac ataacttgca acagatggag ctaagtacac
    32101 atatgcactg tcatttacaa aaagaccaac attttcaccc ataagttttg gagattttaa
    32161 aaatggtggt atgtaaggtt cttgtcttaa gaagtctgta tacacaccca agaataaact
    32221 tgtcatagtt gtatttccgg cagccactaa tgtaactaca tcttccttat ctattccatt
    32281 tctttcatat attgttttta atagtggatt tatagtttcc tcaactatag ctttatgaag
    32341 tgtctctaat ccatttttct tagttgaata tataattcta tttataacat ctgctccata
    32401 ttttatctgt gcatttccag aagatgcttt atctactacc tcttttgagt ataggtctac
    32461 taaacaaaca actactgaag ttgtaccaat atctattgca actccgtata aggaattttc
    32521 tttatttcct tgttctatat ttatgattgt aagtttcttt tgtttttgaa catatgttat
    32581 tgtaacctta aaatcactct ttctaaatac agttggcatt tttctaagta tatccaatct
    32641 aaaatctatt tcattatatc ctaggttatt tctaacatat ctttccaatc tatctacatc
    32701 acttatatta tcatctaaat ttggttcttc catttctatg tatttctttt ttatatttgt
    32761 tttaaattga aggttatgtt cttcaattat ttttttagct ctttcaaaaa tttccctatc
    32821 ctctttttta ttactacctt ctatcttcat accatgcata gaagatgata ctttagaagg
    32881 aacttcaatt tctatatctg atattacctt tgtacaacaa gctagtatat aaccttgctc
    32941 ccactcatca tctgttatat gtcttgtttt ttctgtatca acttttccat tcaataattt
    33001 tactttacac ttcccacaag acacgtttcc attacaagga gcatctatga atatatctgc
    33061 atttcttgca acctctagta atatatcccc ctcattacaa taaacctctt tattgtttgg
    33121 tgtaaaactt acttttatca tgttatccct cccaatttgt tctatatatg ataaaaggaa
    33181 agtatagcta aatttgcgtg cactcaaatt ttactatact ttccccaatt ataataatat
    33241 cttaatcttt aattattcta atccagcctc gtattcttta tcacttaata acgtatcaag
    33301 ttcagccaca tcagctagtt ttacttttaa tatccagttt tcatatgggt cttcatttat
    33361 acattctggc tcatcttcta atttttcatt aacttccaat acctcaccat taacaggaga
    33421 tattaaatca gaagctactt tagaagactc aactactcca aaatctactc ccttagttac
    33481 agtatcttct acttctggtg tttcaacaaa caatatttct cctaattgat cttgagcata
    33541 gtctgttata cctatatata caacatctcc atcaattact tttacccact catgatcttt
    33601 agagtatttt aattctggta ataatttcat ttcgatagac ccccaatatt atattattga
    33661 ttaaattact taaatcatat taatattata tcatattatt ttaaattttc catcaattac
    33721 attacacttt ccatagctaa tgctggatga cctttttctt ctaagaaagc taatactcct
    33781 tcagaatcgt cagctatagt ttcatcacaa accatatcac agaagttttc tattccagtc
    33841 atttctttaa ctgtagcatt taatttatca gctacataat cttttaattc ttttggcatc
    33901 caaactattc tttctggtcc accttctgca taagcgaatt ttttagaaga tataaaatgt
    33961 cttccgtgtc ccataaatcc tggagtttga actcctccac ctgtcataga agcaagttct
    34021 ccgaaagtca taccaactgg agtaacactt gcaaattctc tgttaactac aacaaatcca
    34081 tttgcttctg gcattatacc acagatacat tcgaagcatc cacaagaagt cattgggtct
    34141 tctagtatag agtataatgt aacagattca actgcacctt gagatatttg gtttacagtt
    34201 tcatttactg aattccatac acctgttcta tcatctaagc actcgccttt ttctattggt
    34261 tgacaaggac ctgttgggtc taattcttta gtagccttag catctaacca gctaactgct
    34321 ccacaaagac caagtctttc aggagtaaca acacaaacgt gagctggtgc aaatgattga
    34381 cataagttac aagaatagaa agtatcaaca ctttcatcaa ctaatgaagc taatctttca
    34441 tctctagcat tgtacttagc tattgcttct ccttttaatt cagaaacttt ttcagcatct
    34501 gtaattatag ttatttcaca cttatcaact actgattcaa attcatctaa catcttagca
    34561 tataaaactt ctcctatatg ctcaagtcta aatcctttat caaatgcatc tttagagatt
    34621 cttacccaag ccatatctct ttgtccaacg tgcattacac cttctatata gtttaagaag
    34681 tagtggaaac gtctttcaag aactggctcg aaatcttctt gcatattttt accagctatt
    34741 ttaactatta cagcaagtgg taatcttaat acaccatctg catcaacttc atctatattt
    34801 ggccctatta tttctatctt atggtcttca acttctgttg cttctttctt aacaacaagc
    34861 tcccaagctt cagttctgtt tccaccaaac tcagcaaaca tatcgctctt tctaattctc
    34921 tcaccttcaa atgctgctgc aaatgaaact gggataggta tttcagtaac ttttattttt
    34981 attcctctag cttctaatga agtagctact atcttatcgt aatctttttg agttaatagg
    35041 ttcattggaa cttcaagaac tgtttggtca gttataactg ggaatcctaa agctattgct
    35101 ccagcacctg cagatacaac taattcactt aatggtccaa atgcattaac aaatgcagga
    35161 actctattag ctgtgtactc taataatccg tttaaatcac caggagttaa tccaccgaat
    35221 attaatgctg ctcttactgc aacagataca acgtgtataa cagaagttac atcatatcct
    35281 agaggtataa ctcttagctc aagacccatt tttactccag cttctatagc ttggtctata
    35341 actttaccaa ctaagaaagt tagtaaacct ttagattggt aatcttttat aacttttgct
    35401 gctgattctg catctggaca ctcaccaaga acaactgcaa caccaggtat atctcctgta
    35461 actaatggta caccaagtga tctgattata gggtcagtta tatgacctgc acatggctca
    35521 ctatatggag catccatagt tgaatatttt aatgcttcaa ttacttctgc tgctaaagct
    35581 gtagctaaac cagcattaaa agcatgttct agtaaatgag ttctatttat taaagatttt
    35641 actacttcta aagcaccttc taagtcccct aaagtgttca tcttttgtcc tgttgcagca
    35701 tatatacaag gtaatgaata tgctgtatca gggaaagcaa ctttatgctc ttttccattc
    35761 ttttctatag cttcagctaa catagcttga gccgcaccta aagcttgttc tgaccctgta
    35821 aagattatat tatatagatt cattctattt ccccctttaa tatttacacc tattttttat
    35881 taactatacc ctaaaaaccc tagaaagcaa atccaccttc atttaactct aagaaagagt
    35941 ctgcatataa agatgccccg ttgattatgt cacaagattt tacagttttc attaattctg
    36001 ggtcacatgg attcattata gctgaactaa atccattagc cattgccatt gctaagaatg
    36061 cactatctaa aacaggtcta acatgcttag gacatccatt agatacgtta gataatcctc
    36121 ctgtagttaa aagtcccatc tcagtcatca tttttatagc ttctaaaact tctacttgtt
    36181 tttcttgcat accttttata actaagcata atgggtcaaa tagtatatca gttggctcca
    36241 ttcctaacat taagcctttt tctaatattt cttggcagta agccatacgc tcatcattat
    36301 ctcttgggat accttctttt gcacataaac ctataaccat tgcttcgtat tcagctgcta
    36361 tatctattaa atcaaatctt gagccagcat cagcagagtt tattattggt tttgcattag
    36421 ttctatcata aactttaagt ccagcttcga tagctttttt attagctgta tctaatgcta
    36481 taggaacatt gttgaactca gattgaagta atttgattcc ccatgtcatt atttcttcgc
    36541 catctctttc ggcaggtcct atattaaaat ctatatagtg tgctcctgct tctaattgct
    36601 cttttgctct ttttaagatt ggagctgggt ctctttctgc taatgctttt cttattgaag
    36661 gtgatataca atgtattctc tcacctataa tcataaattt ttccatttat aatgtccccc
    36721 tttaaattta atattaatag ttagttaata ttttattagt ttgtttggca tgctttttct
    36781 tggtatcctt ttaagaactt aggtaattcc atagattcct ctggtcctat aactacattc
    36841 catcctggta agttatcttc tatatcacct ttaagtactg caacttttcc tggaatgata
    36901 aggtctttac aattagttac ttcttctacc ttactttctt taatgaaagc agagattgag
    36961 tttccaccaa atttaccagc agcccaagat gtaagaactg aatatccacc tgcatctggt
    37021 attactaacc atactggaac ttttgatctt tctatatcac cagcaactat gaagtaagtt
    37081 aatgcaaagt caacagtaac taatactgga gaattttcat ctggattgtt gattggataa
    37141 atctttggtt caactctcat tggtctttgt gggtcagtgt atatgttttg tcttagtgca
    37201 aataatggta atgccttagc ataactaata tcatctatta ctattataga accgtatttt
    37261 atagtgaata ttgatgataa agcaacttcc atcatagggt ttgaattaga taatctattt
    37321 gcaaatacta ttgaaggata tccaaatgtt ctatcttgct cttttaaagc tgttcttcta
    37381 acttgtatag cattagtgta agtatctttt atgttttctc ctgttacatc taatactaat
    37441 tctttatatc cagcggcttg aattaattca actgtttcat ataattcttc taagctacca
    37501 gcttttacac ctaatggtaa acttgctcct ttaactactt ctatcatatc tttgtagttc
    37561 tctttagttg ctccatatac cattggtcta gcatctttta atacttcaac agcttcttta
    37621 actacttgtg catcatcaca agctaaaata taagctactt ctaatccact gccttttatt
    37681 ttatctatta attttaaata cgcatcttta tctccacaat actctaaaac agccatttca
    37741 actttcattt gttcaccaat tcttacatag tcaacttttt tcatgttagc tattttagca
    37801 tctactgctt catcactcat acaagtacag aatgaaactg catatctatt tctacttact
    37861 aatgtttttt catgtctaaa taatactgtt tctccaccta gttcatactc agatgcacca
    37921 gcaccaactt ttaaagcttt cattaaaggt gcagtagcct ctgataattt tgctatagcg
    37981 tcatcagaca tatgtgggca tttacctact tctacagctc ctgaagcaac cttcatagag
    38041 aaagccatac aagttgggaa tccacaatcc ttacagtttt tctttggtgt taatttaaat
    38101 atatctaaag cttttaatgc cattattttt tccccctaac cttaacaatt taattaagct
    38161 aatgcgttaa ccaattcttt tatagtttct attgattttg gatgacgaag tataactgcg
    38221 tttgaaccac ctactaaaac acttgctgca gttgaaactt ccattgctat agttctttct
    38281 tctggacaac cccaatctgg ctcatcttct attggagcta tagcttcttt aacatgacct
    38341 acttcaaaag ctactggtgt tatgataggc atttgtaatg tcttatcatt ttgaccaaat
    38401 gctgcaagtc taattctatc catagtagat gcaacgtact catatccata accaactgct
    38461 gaacatccaa cattcataac tatattttca cctttaacgc ctagttgagt taacaatacg
    38521 tttaattgtt tagctaggtt tatatcaaca gaagattcag ctcctacttt atgtgcataa
    38581 gccataccag ctgatgctcc tactcctttg tagttatctt ctactgctga cataaataag
    38641 cagttatgtc catccaatgt ttgagctaat ttttcaaata atttaccatc tttttcatga
    38701 tttcctgaac cagctacaac taaaggtaat tttattgctt caattactgc cttagctaca
    38761 tcagcacatt catcaactga cttatctaat ccatttgggt cagaaccatc aaattttaaa
    38821 caaataaaat ctgcttgtgt attagcttca acatatttag cccactctac tggacaatta
    38881 gctacatctt tgtataattc cttatatgaa tcagtccagc tttcaggata aacgtctgat
    38941 atttgtatac ctatttttgg agaattacct acttctccat caaaactata aaaaggtaat
    39001 acattttccc cacctaattt aattgctttt tcccctattc ctacttcaac ttctgatatt
    39061 tttccagaat atttttgagt agacatttta aatgccatat ttttttcccc cttaagccta
    39121 ttttaattct aatttagcaa aaatttcttt catagccact ttagattttg aatcttcagg
    39181 taaattaact aaaggaatac ctgtagaatc atattcatat atcaattcat ccataggtac
    39241 aacaccgatt agctctaggt tatgcttttc aatttcttct ttaacaccat cattcataac
    39301 cccatttgga actttattta caatcaaaag tattcttcca acacttaact ttagttcctc
    39361 agctaaatct cttattctag caacagcttg tatgctacgt cttgagcaat cactaaccaa
    39421 taaaagtgta tcaacatgtc tagtgacttt tctacttaga tgttccatac cagcttcgtt
    39481 gtccatgact aagtatttgt aatgaccaga tattttgttt acttgttctc taagtatccc
    39541 atttacaaaa cagtaacatc cttcaccttc tgacctaccc attactaata agtcatatcc
    39601 ttcgccttct tcgattatag aatttaatct aaattgaaga tattgtgcct ttgtcatacc
    39661 accagggaat gcattgccta acttttctct ttgatttact tcttctctta tttctcctat
    39721 tgttgcttca acttcgatac ctaacacttc atttatgtta gcattggcat cagcatctac
    39781 aactaatact ggtccctttt tgtccttaac caaataatca atcaaaagcc ctgtgagact
    39841 tgttttacca gttccacctt ttcctgcaac agctatattg tatcccattt taagacttcc
    39901 cccttaaatc tagccacaga gccttatgta ctctgtctgt ctattataat ttaggtacag
    39961 aatgaacaca ttctccatgt acatcatgaa gtgcttccat tagcccttca gataaacttg
    40021 gatgtggatg tattgcatcc cctacttgtt ctactgttaa tcctagatga acagcaagtg
    40081 acaactctgt caataaatct gtagcatgag gtcctactac tgctgcacct attatcttat
    40141 cagtttcttt gtcagctata acttttacaa atccttggaa atgtcctata gcttgtgctt
    40201 ttccaagacc tctaaaatca aattgaccta cattgtattc tacaccttca gcttcaagtt
    40261 gcttttcagt cttaccaaca ccagcaactt caggttcagt ataaacacat cttggaattg
    40321 ctctataatc tactacctta gtcttaccta aagcattttc aactgctacg ataccttctt
    40381 tagaagcaac atgtgctagg aaaggagtat ctattatatc gcctattgcg tatatacctt
    40441 ctacattagt ttcaagatgt tcattaacta ctacttttcc tctttccatt tcaattccta
    40501 tatcttctac tccagaattg tcaaggttag gtcttctacc aacacatact aatgcatatt
    40561 gtgcttctat aacctttcca ttagaaagag ttgcaacagc cttaccatca actacttcac
    40621 aagtttgtac tccaatacct gtaataacct taattttatc tttcttaaat tgtctaagta
    40681 gttgtttagc tacatctttg tcttcattta atagtatttg gtcaaccatc tcaactatag
    40741 ttacttctgt tcctaaggct ctaaagaact gccctatctc acatcctata actccaccac
    40801 ctactattaa catagactca ggtatctctt caagtccaag aacttcatca ctagttatta
    40861 caacttttcc atcatatggg aacattcttg gtacaactgg aacagaacca tttgctagta
    40921 ttatcttatc tgcttttata gtttctactg ttccatcatc tttagttact tctatagtgt
    40981 ttttatcaat taattttcca aaaccattaa ctaagtttac tcctcttttt tcaaataaga
    41041 actctatacc acttattaat tggtttacaa ctttattttt tctttccatt atggcagtga
    41101 agtttggctt aattgtacca tctatttcta taccaaaatc ctttgcttct tttacagtat
    41161 tcaatactcc tgaagaagca agaagtgctt tagttggtat acatcctgca tttaagcaag
    41221 ttcctccaac tcttcttttt tcaacaactg ttacatctgc accaagcata gaagctttta
    41281 tagctgctac atatcctcct ggtccaccac ctactactac tatcttcatc tttaattccc
    41341 ccaaacctaa tataatctac aatcttgcaa tactataaac ctgcggcatc cagtatagca
    41401 ggtatattct cttctgcccc aattgccatt atatgaacac catcacataa atcttcttct
    41461 tttaattgtt tgataagttc ccctgccatt tttattcctt cacttaccca gttttctttt
    41521 ccagctgctc ttaatctttc gatttgttca tctggaacaa atattcctgg tacatttgca
    41581 gtcataaatt tagccattcc tggtgatttt aaaggtacta ttcctgctaa taccttgcaa
    41641 tccatatccc ttgttaattc tctaaacttt ctcattgtat ttatgtcata aagtgcttgt
    41701 gtttggaaaa atttagcccc tgcttttatt ttctttttca tttttaataa ttgaacttct
    41761 attggagaat attctggagt tactgatgct cctagataaa aatctggaga accttttaac
    41821 ttattaccag ccatgtccgt acctgccatt aaagtctcag cagtttgaag tatccccaca
    41881 gaatctaaat caaacactcc cttagcttgt ggatggtctc ctacgctagt atggtctcct
    41941 gttagtgcca acagattgtt tatcccaaat acacctgctg acaacatttc tccttgtata
    42001 gctattctat ttctatctct ccctgttatt tgaataactg gctctaatcc agcatctttt
    42061 aataatttac atgtagcaag agaagttgct ctcataactg ccgattgaaa gtctgttaca
    42121 tttgctgcat gaactcttcc aactaacggc tttgcacatt ctattaaatg tgaaaggtca
    42181 gtcccttttg gaggagccat ttcagtagta actgcaaatt ttccactttc taatgtttct
    42241 cttaataagc tcatctctaa tccccctttt aaccttctaa aaaaactttt atgaatttgc
    42301 tgctgcttct ttctttttct ttgcacttaa acttcttgga ttattttgct tagaatagtc
    42361 ttttggtggt cttatttctg ctaagttatc taattgtcct atagcttcta gtctttcata
    42421 tatctttatc caagcacaat cattctctga gtttacttca cacttaccat ttttagctcc
    42481 accacaagcc ccattcataa gacctttagc acacatagtt actggacata tcccacctgt
    42541 ccaaccaagt tcacagtctc cacaagcctt acaggcttct tcatattctc caactctttg
    42601 tacttcccct ataaacaaag tattgttggc tggataaact ggcttatctt ttaaattctt
    42661 aactattgtc tgtgtaccat ctccacatgc taaagataaa actgcatcag cttccttagt
    42721 ctcttctttt agagccttta aatccttttt agactttaaa aggttacaag cagggtcaag
    42781 cattacatat cctaagattt ttttgccttc accttcaaga gtttccttca tttttaaaac
    42841 ttcttcttcc ccaccacttt tacaagttgc tgcacattga ttacaaccaa ctaaaaccag
    42901 cttgtcaaaa tcttttaagt accctagcac ttcttctaat ggtttatttt cagaaattat
    42961 catatctact tcccccctaa accttccaca tatatatatc tatttattgt tttgtaattt
    43021 gcaagcctta actacatgtt ttgcaagtat agatgttgta actgaaccaa cccccgctgg
    43081 aactggagtt atcattgata ctttgtctaa aactgcattt gtatcaacat ctccacataa
    43141 atttccttct tcatcaacat ttataccaac gtctataact accgctccat ctttaacaaa
    43201 actttcatca accatcttag ctctaccaat agctgctatt agcacgtctg cctctgctgc
    43261 tacacctgat agatttttag tttttgaatg acatattgta acagttgcgt gttcacttaa
    43321 taaaagcatt gatactggct ttccaactac cattgatctt ccaagaactg ttaccttact
    43381 tccttttaaa tcaacattat agtgttttaa tatctcaact actgctgtag gtgtacatgg
    43441 tggaaatcca cttttatccc cttccattac cttagcagag tttattggac taaaacaatc
    43501 tacgtctttt tccggtgcaa taacatattt tataacttct tcatttaagt gttttggaag
    43561 aggtctaaaa cataatatac cattaacatt tttgtcatca ttaactctct ttaatacatc
    43621 aatatattcc tcttgtgtta tatcctcagc taactctaac acttctgttg ttatacctat
    43681 gttttgacat ctctttagtg ctcctctttc ataagataaa tcatcacttc ttgccccaac
    43741 tctaactatt gttagtttag gatttatacc ttctttaatt agtaaatcga cttcttttat
    43801 taattcttca ctaatcttat cagctacagg ttttcctttt ataatttgtc ctttagttga
    43861 cattccttcc atacattcac aactccccta caagcaaact taaattaatt tattctatat
    43921 accacatatt aataacatag tatctacttt cgtcatttaa aaattatttt ccaagagctt
    43981 tttcaacttt ggcataaact tcatcacaaa tttttacacc atcttcaact aacttatcta
    44041 cttctgtttt taccttatta acatattctt tatcttgtat agaatttata tttataacta
    44101 catttaattg tccaccaagt atagcagctc ttaaacactg aactcctaca ccaacatcac
    44161 ttatagcaag tcttgaacct ttatcaacta aatcttcatg taacttaata gcttcatagc
    44221 aaactcttac tatgtttaat ggtacttcac aagcaacttt taatgccttt tccattgttt
    44281 ctgcttttat tcttttttct tcttctgttt ctttaggaag cccgtaagct tttgataatg
    44341 gtaagaaaca ttctgcatca tcatctatca tttttaataa atctttttct aactttcctg
    44401 ccttacttaa tatctctttt acactttctt catactcagc atacttcttc ttccctattg
    44461 taaggttaca taccatacta cctaaagcca tacctattgc acctactagt gcagcagctc
    44521 ccccaccacc tggtactgct tctttggaag atagtacttc tacaaaatca acacaagttt
    44581 tatctgctat tttcatgata atcctccttg aaaggatgta ggaaaatatc tcaaattgtt
    44641 cgagatattt tacgaactat tttaagatat ctcctactct ttatttataa attaatttcc
    44701 ttagaataat ccagctatta ctccattttc atcaacatct attttttctg ctgctggaac
    44761 ttttggtaat cctggcatct tcattatttc tccagtaagt gcaactataa atccagctcc
    44821 tgctgaaatt gttgcttgtc ttacagttat tctaaatcct gttggtctac ctaatttagt
    44881 ttggtcatca gttaaagaat attgagtctt agccatacat actggaactt tagtaaatcc
    44941 aagtttttct aagttagcta tttccttatc agcttcagga gtataatcta caccatctgc
    45001 tccataaatc ttagtagcta tagcatttat cttgtctttt atagataaat catcttcata
    45061 gcagaatcta aagttatttt cttcttcatc caataatctt aaaacttctt tagctactgc
    45121 aattccacct tctccacctt ttgcccatac ttcagaaaga gcaacattaa cacctaattc
    45181 cttacacttg tcttcaacaa gtttaagttc agcttcagta tcaagtggga atctgttgat
    45241 tgcaacaact gctggtaatc catatacttg agttatgttt tcaacatgtt ttaataagtt
    45301 tggaagtcct ttttcaagag cttctaggtt ttcgttattt aagtctgctt tagcaactcc
    45361 accattgtat tttaatgctc ttacagtagc aactattata acagcatctg gttttaagtt
    45421 tgccattcta cattttatat ctaagaattt ttctgctcca aggtcagcac cgaaaccagc
    45481 ctcagttatt acataatctg caaagtgcat agccattctt gtagctataa cagagttaca
    45541 tccatgagct atatttgcga atggtccacc gtgtacaaat gatggtgttc cttcaagagt
    45601 ttgaactagg tttggtttta aagcatcttt taataatgca gccatagcac cattagcttt
    45661 taattgtcta gctgttacag gttcaccttc gtagctgtat ccaactatta tgtttcctaa
    45721 tctttctttt aaatcagata tatcacttgc caaacagaac gctgccatta tttcagaagc
    45781 aacagttata tcgaatccat cttgtctaac tgctccatca ccttttttac ccataccatc
    45841 aacgatattt ctaagttgtc tatcgttcat gtctacacat cttctccaag ttattttctt
    45901 agggtctatt ctaagtgcat ttccttggtg aatatggtta tcaagcatag cagctaaaag
    45961 attgttagca gctcctatag cgtgaaaatc tcctgtgaag tgtaagttta tatcttccat
    46021 aggaacaact tgtgcatatc ctccaccagc tgctccacct ttaacaccaa atactggtcc
    46081 tagagatggt tctcttaaag caactaatac atttttgtct agtttagcaa atgcatcagc
    46141 aacacctata gtagtagtag tttttccttc acctgctgga gttgggttta tagctgtagt
    46201 tagtattaac ttagcttttt taccagtctc tctttttagt agattgtagt caacttttgc
    46261 tttgtattta ccataaagtt ctacatcatc ttcacctagt cctaattttt ttgcaacctc
    46321 tctaatatct tgaggcttag cttcttgagc tatttcaatg tcagatttaa atcccataac
    46381 tgaatctcct cccacaacct aaatagattt aaaatataat ttttgtaaaa attgtattaa
    46441 tatgtaaaaa ttatatttta taagataatt atacatgtaa aattacttaa aaactagcta
    46501 ctaagctatt aaaatattca aacttaatag ctagttattt atctaattac ttacttatta
    46561 cctatctatt gcctatgtct aacctttaac caacttaaaa tcccaaatca aaatttctat
    46621 ctattttatt tatccttaag tgacattaat ttatctttta ttgctttaat ctgttctttc
    46681 gttgtttcac tagaatcata tggagattga ttagctctat cagaatcaat aacatcttgg
    46741 ttataataaa taaatcctaa agattctcca tcttctaagt tttggattat aaattcttca
    46801 tcttccttat ttctaatttt atttcctact acaaatactt tatttacacc tatatcatgt
    46861 ccaagtttct taacttttct ataagtctgt agacttctct ctcctggttc tacaactact
    46921 ataaaagcat ctacaccttg ggctgttcct cttcctaagt gttcaattcc cgcttccata
    46981 tccataacca ctacatcttt attttgtagt attaaatgtg agcagagtct cttcaaaaga
    47041 acatgctctg gacatacaca tccagtacca ccagaatcta cggttcccaa tgtaagtaat
    47101 cttactccat tgtattcttt acagaaattt tcagggatat cgtctacttt aggattcatc
    47161 ttaaacattt ttccaaatga acctacagaa gcagctgttc tatctgaaac taattttttc
    47221 atttctgata taggtactat tgattcatat acttcttttg gaaaacctag tgctaaagct
    47281 aaattagcat cagggtcggc atcaacagca acaactctgt atccgtcttc agcaaacatc
    47341 ctagagagca ttgaagaaaa agtcgtttta cctactccac ctttacctgt tattgctatc
    47401 ttcataatcc ctaccacctt ttattactat ttgcttttta gtagttaatt ttacagttaa
    47461 atatttttta tactctatat ttttatacac taaaaataaa ctacagctag tccttacagg
    47521 aaccaattaa atttacccta ctagcttttc aaagcagcat gtatagtttt attattcttt
    47581 aatattgttt atattttatt tattcagtat attcattata ttttgatgtt ctttacttta
    47641 atatttgact ttattcaact ttattcaacc agaaacttct tataaaaacg tttattctat
    47701 aacttcacta ttttttaagc ttcagccttt tctgccatct tttcttcaac taatgcttca
    47761 aagtgaacac gttttttctc tatatcttct attattgtag ctgctaactc ttttggattt
    47821 gtatttacag taaatgtagc tccaacttta tcttttaatt cactagttaa tatatccact
    47881 gctcttgaag aaccagctat tggaggcatt attcctaaat aagtgtctat accagaagct
    47941 acaacatagc atcctatagc aactgctttt tctgacatcc actctggagc tatacctaca
    48001 actggaaggt cacacatatc catatctaag taattagctg ctgctccaac taaatctagt
    48061 atacgactta tatcaacaca agaacccata tgtagtactg gtgggattcc tactaattta
    48121 cagacagttg caagaccttt acctgcatat ttttcagccg catcagattc cattaaacca
    48181 aacttagctg ctgctgaagc tccacaacct gtagtaacta ctattatgtc gtttttgatt
    48241 aattctttca ttattgttac gtgagcctca tttgaaactc ctttagcatt gttacatcca
    48301 actacaccag ctgctcctct taatactcca gattttaaac agtctgttaa tggcttaact
    48361 gttcctgctg ggtctatatg agagtttaca actctgtcta attgatttac tactgcttct
    48421 acactatacc caactgttgc gcctgatttt aattcaggta taagtacttt tgatttatct
    48481 ctatttttaa agtttaaaat agcttcttta actattgctt tagcatcatc aagtgcttgt
    48541 tcttctctaa attcaatata agttgaacct gttatcttag cttttggaga agttgttaca
    48601 aatttagtat ggtaacaatc tgcaactcta gctaatgcag ggaatataca ttgaacgtca
    48661 actattacag cttcaactgc tccagttatt attgcaagtt cttgttgatg gaagtctcct
    48721 gctattttta caccatgtct cattgtaatc tcattacctg tacaacacat acctgctaag
    48781 tttattccat cagcaccaac ttctttagct aaagctacta agtctggctc ttctgatgct
    48841 aaaactatca tttctgataa tgctggctca tgtccatgta atattatgtt aactttattt
    48901 tcttctaata ctgctaaatt cgcctctgtt cttcttggca ctggagttcc aaataagata
    48961 tcgcttagac gagtacctat catagaacca ccccaaccat cagccataga agttctaaga
    49021 ctcatgtgta ttaaactatc tatatcacca gtacatccta tatgagtaga gtgcattatt
    49081 gttgcaattt ctctatctat agctcttggc tctatagcgt attctttcca tattttttgt
    49141 cttggttctg gtgcattttt tataaatctt aatgtcccaa aaggttttcc aaattccatt
    49201 aatgcaattt ctgccacttc atgtgctaca tcatagatat ctctaccttc tgtctctaca
    49261 tcccattctt tagctaaagt aattaactta gcttcgtctc ttattttata gtttccattt
    49321 ggatcagcta atgctaatgt atgtgctata tctctagcat ggtctgaatg ggcagctgtc
    49381 ccaccagcaa ccattcttgc aaagtttcta cctactatag tatgctcatc tgctccacat
    49441 aacccccttg gagtcttagg gcttattcta catggtccca ttccacatat tctacagcaa
    49501 acaccttgaa gaccaaaacc acattgtgcc ttaaagcctt cttttctatc atacattgtt
    49561 tctacgcctt cttctctagc tttagctatc atcttctggc tgtttaaatc aattgttaac
    49621 attttttcat ccatattcct atcccctttt tttgattttt aaaatccccc aggtgactga
    49681 cttcatgtca taaaataata aaataaatgc tttctaagtt gattatatac taattttcag
    49741 tgctttgctt tagatttaaa tattttttta acaaaattag ataatacata aaaattttat
    49801 tttctacact taatttaagt tgattttatc gcttgttttt ggctatttgt taatatctaa
    49861 acctactttt ttgatacttc agtttaatta aattatgttt tgattttttt aaatcaaatt
    49921 tgaaattttt ctagtcattt ttatattatt gcagattgtt tgtgtattta ttatctttca
    49981 ctactgtttg gacttattac agatttttac tccctaaact taattagtaa aaacttctta
    50041 gaatagcatt ttttggacta atttttttga atttttttat ttttcctact ttaatattaa
    50101 ttatagcttc aaattgaaca tttgtatata ttcatttgaa gctataatta ttttttatat
    50161 aaaacttttt taatacagca ttaatttaga cattttgact attttttcta ctttaattca
    50221 tttatttcaa gcgatttatc ctatttcata tttttagcta caatagcccc atatgcaata
    50281 gaatataatt tagattcatg tgaatcagct cttgacacta aaactatagg agcttttgca
    50341 cccataatta tacctgctga tttagagtct gccatatatg taaaggcttt ccctattcca
    50401 ttaccaacct ctattgttgg aaccaatatg atatctacat ctccagatac ttcactttta
    50461 aaccctttta tctcactagc ttcttttgaa acagctaaat caaaagccag aggaccttct
    50521 acaattacat tttcaccaaa ttctccttct ttacaagctt ttgctaacat atctgcatct
    50581 acagttgctt gcatcttagg atttactttc tctttagctg ccaaacatgc aacttttaca
    50641 gtttccattc ctaaagcttt tgcagctttt atagaatttt ttaatatctt tgccttttgt
    50701 tcataatcag gagctatatt catacctcca tctgtagtta taagtaattt atggtatttt
    50761 tctaactcat ataccataac atgacttaat aaactatcag ttctaagacc atagtcttta
    50821 tttaacactt cttttaatat gacagatgta tctaataatc ctttcattac aaagtcggct
    50881 tctttacttg atactaattt aactgctatt tctgcacact ctttgatatc atccttatcc
    50941 actattttga taccacttaa atcaaatcct atttcttttg atatttctct tattttgcct
    51001 tcatttccaa ccaatatagg agtaattata tttctttcta cagcatcctt tattgccatt
    51061 aaaacttctt tatcatgagc tgctgctaca gagagtacaa ttttctctcc tcccttaagt
    51121 tgttctaaaa tatcatctaa tttttttatc aaaagtaacc cctcccttat atatatttaa
    51181 ctaaataata ccatatttgc tatacctttt ctcaatttat tttttatgtt ataaagaatt
    51241 tatataacta aaagacagtt taatatttta ttctgggatt tcatcaataa ctcttaaaag
    51301 ctttgcagga acaccaccta caatagtatt ttctgcaaca ttttttgtta caactgctcc
    51361 agcagcgata attgcattat ctccaatagt aactcctgga actacagtta cattagcacc
    51421 aatccataca ttttttccta ttgtgattgg agaaggataa gttgtaccac gtttctctgg
    51481 tgcaatacca tggttaagtg tagccaatac cacattatgc ccaatttgcg tattatctcc
    51541 aatctcaatc cccccctggt cttgaaaatg gcaactgcta tttataaaaa cattttttcc
    51601 tattgtgatg ttttttccac aatctgtata aaatggtgga aacataaaaa atgattcatc
    51661 tacctttttt ccaattaact cagaaaataa actacggact tcttctggtt catgataaga
    51721 agaatttaac ttacttgtga ttttcattgc ttcattactc aacttaacca taaattcatg
    51781 tatttctgat ttactagaaa caggttttct ttgattgata tgtgttaaaa attcattgat
    51841 attcatttta tacatccttt caatatgtgc tttaatttat ttgtacattc taaataatat
    51901 tttaataaaa attaatttaa tttattttta ttaaaatatc attgcttctt ttagtgtaat
    51961 atacaattat atctatatca aatatctata gtaaatactt aactatactt aaaaagcata
    52021 taaattgata taattatata atagataagt taatattgag gagggataat tatggaaata
    52081 agagtattaa gatatttttt agcaattgca agagaagaaa gtatatctgg tgcggcaacc
    52141 tttttacata taacacaacc aacactttct agacaaatta tggaacttga agaagagttg
    52201 ggagttaaat tattggttcg aggaaataga aaaatcacct taacaaatga aggtaggctt
    52261 ttacataaaa gagcagaaga aattatatca ttagttgata aggttgaatt agaatttgac
    52321 aatcccaatg agattattag tggtgatata tatataggaa gtggtgaaac tgaagctatg
    52381 cgacttatag ctagaactgc ccatcatttt catcaaaaat accccaatgt aagatatcac
    52441 ctttttagtg ggaatgctga tgatgtgact gaaaaattag acaagggact gcttgatttt
    52501 ggtattttaa ttgaacctgc aaatatacag aagtatgatt atgcacaaat tcctgctact
    52561 gatgtatggg gtttactaat gcgtaaagat agtgcccttg catcacaaag cacaataaat
    52621 ccaaaagatt tatgcaatat acctcttatt atttcaagac agacacttgt tgataaagca
    52681 atttctaaat ggcttcaaga cagtaatgaa aaactaaaca ttattgcaac atacaattta
    52741 gtttataacg cttctctttt ggtagaagaa ggtctgggct acgctctgtg tttagataga
    52801 ctcgtcaata ctacagaaaa cagtaatctt tgttttagac ctctatctcc tcctttagaa
    52861 gctaaattaa atattatatg gaaaaaacat caaatatttt caaaggcagc agaaaaattt
    52921 ttacttcaaa tacaaaaaga tttttcttct atcatgttgg atacatctaa gttggataca
    52981 cctaaagaaa aataaatcat aataaaaggt gagagtgtct caaaatgaac tttgcactgt
    53041 ataaggcact cttttttata caaagtaaaa tatatgttca tcatttcagc actaaaaaag
    53101 aggcttatct ctattttgag atagccccac ttaaccaata aaattaaata caacttaaca
    53161 atatccttac ttatttattc taagttctct tagacaagca atagtaattt catcttgtgg
    53221 atttaattca taagctcttt ctatatagta agttgcatca tcaatatcac cattatttaa
    53281 ataagccatt cctaaattgc aaagtatttc tgggtcttcc tttatcttag ccgcttgttc
    53341 aaaatactct attgctttat ctaaattatt cttataagcc tcacaaagcc ccaattccac
    53401 tatagtatcc acttgattag gctttattat caatatcttc tcaagataca tcttagcctg
    53461 ctctatttcg cccataccct tatatccaag tgctatcata aacagcaagt tccaccaatc
    53521 catatgttct tcttctaatg gaagtaactt ctctaatcct tccttaaact taccttggaa
    53581 tacaagtgta tatccttctt catattgaac tttaaagtcc atcttgccca gattctcttg
    53641 tacctcagct actaaatcag catctaaccc tagccttaac gcttcttccc aagtcagctt
    53701 agtctttaaa tattgacctt gattataata atggtagcct aagtgataat aacctaatgc
    53761 aaaattctca tcaacatcaa ttaccttttc aagcttagcc atggcttcaa gtaagaatgc
    53821 attcattgcc ttatcatcca tatctttttg atactgttta gctatctctt ggcaaacaat
    53881 cgcatagtta tacattgcat ctaaatcatc tggatacatt gttataaatg cttttatata
    53941 tattaaagaa tctgtatgtt caccaatctc aaagtatttt ctcgacatat atcccatata
    54001 cgatttcaaa tccaaatcaa tatcttttga taaagcattt aaaaacttct catactctgc
    54061 attgttttta aacttactat ctattccaat tatatatatc attgcatctg ctatagacat
    54121 tgaatttaac ttatcttgag cagtcttttc ttttatccct tttactaata cctcattttt
    54181 tataggtaca tctaatccac cttttggcac ttcatagctt tttaatttaa actctccacc
    54241 atgttttata gttataaaag ctaattcttc tgcttttttt agcaaatatt tttctatctt
    54301 aaaatccatt ttatcctcct aaatacttaa atctctactt tatgagtttt agatttctca
    54361 aatatttttt tatcatcata ctcaaataag actacatttt ctacttctct tatttctgta
    54421 tttatatcat tttttaaatc cacaacatta aatctaaatg gctcaaaatg aacatatttt
    54481 attatatgtt tagctggttt atcaacaaaa ctaggtaaat atgttgataa gttatcatta
    54541 tcttgtaaaa atacatggca tctattctta aaatcatcca catctagctt attaaaaaac
    54601 tgtggtatat ttgatgtttt acccagtgat atatagtcat attttaatat atcgttgaat
    54661 acatcattat ctatgttgat tttttcatta tagaaatcca tcaatatttt atataactga
    54721 ttctttcctt gtgccaaatc aaagtagcca ttttcatcaa aatacttggc aaaaacctca
    54781 aagaatttaa aagggctttt tttataaaat ctgcctataa tatatctcat agataacaca
    54841 aagtttttag aattgtagta tctctccagt atatcttcta tatcctttag cttcaaagtt
    54901 tcttcatagc ttatataatt attgtataaa aactcatatg gagcataatc cttatattta
    54961 aaaccatgct catctgcaac ttttctcata cctgtccctt taatcatctt taaaaagcct
    55021 aattgcaaat gctctatacc tagattaaat acatcattaa aagaattttc aaagctctta
    55081 taatcttcat aaggcagtcc tgcaattaag tctaagtgct gatgtatatt tctataagat
    55141 gctacagttt gtacaacatg agacaacttt ttaaaatcat cccttctacc tactgcatca
    55201 agtgtttttt cattcgttga ctgaacacct atttcaaatt gaaaaagacc ttctttacaa
    55261 tcagccaaaa actcaagcat cttatcatct atcaaatacg ctgtaacttc aaaatggtaa
    55321 gttgtatatc cattatcatt tttcataagg aaatccatga tttccatagc cacttttcta
    55381 tttgcattga atgtcctatc tataaacttt atctgtgata ctcttgcatc tattaaagct
    55441 tttaaatcac tctttatcct gtctaaacta aaatacctta gacctggaat agtagatgat
    55501 aaacagtatt ggcagttaaa agggcaacct cttgatgatt cataatacac tattctattt
    55561 tcatattctt ttggattcaa gttttcataa ggactaggaa tctcatccaa atcttgaagt
    55621 aattccatag gcttattcac tattatctca ttgccttgtc tatatacaag tccatttaca
    55681 tcatttattt ccatctttcc ttgcaagtga agtactaagt ctctaaaaat taattctccc
    55741 tctccataaa gtatataatc cacaaaatca tactttttca ttgcctcata actatcataa
    55801 ctcacttccg gtccgcccaa agctatttta gtattaggtc taattttttt tagattatca
    55861 caaagtttaa ctatatctcc cacattccag atatatgttg agaataatat tatatcatat
    55921 tcatttttat atatatcctt taaaatatag tccaaatcgt tatttatcgt gtattctttc
    55981 atattaactt ctatcaaatc tcttacaaat tcttttagat atcttatagc caaatttgta
    56041 tgaataaact tggaatttaa tgttgttaat aaaattttca aatatttctc acctcttttt
    56101 aagattatac tgtctttttg taccccttat aggttaaaat agtatatgta aagtctaaat
    56161 aatatctata taattaattt attaatttca agtaatgtga ggaaaggaag ttttttatgg
    56221 aattaattga aaaagtatct atcaactctt tatcaaaaag agatttacta cttattataa
    56281 agtctcttga atacactaat gaaaatactc aaattagtga tttcattgac cttaggaata
    56341 atatagtaaa ggaattatgt tttttaactg acactaagga aaaagatttt ttagattatc
    56401 tagaaaaaaa tagcacactc taataaccta aaccttttta aactttaata tataaatacc
    56461 tgatttagaa tttattttta tgcttaatat attatcatta aaggttttcg acataactgt
    56521 tatttgatta aatatagggt ctattatagt attaccttct tcaagtctta taagacttct
    56581 tgggtctatg cttttattat atgccttaac tccaatttta tattttctca atttaacaac
    56641 atattcggac atagaaaaaa taaaatctat attatcttca tttaatttac tatcttcacc
    56701 caaaatggat aatatagatt tttttatgct attaattcct tcattttcta cagttctatc
    56761 ttccatatat acatcatata gaacatttaa aacatttaat aaaatacttt cttcatcata
    56821 atcttcagat ttcaaatcaa tgtacttatc aattaattgt attgctttaa tccttgccat
    56881 ctgaaacttt acaacatctg atttgtctaa ttctatagaa aatcctatta tcttgtcttt
    56941 aatactctgt agtaattcga catactctat tttactatta tttataagat tgtgcataat
    57001 ggaattatac accacagaac ctaataaata atcaaataaa agttcttctt ttttaaaata
    57061 aataacatac ttttttatta gtttaataac ctcatcttca cttttttgaa tattagtatt
    57121 tgataaaatt agtggtaata aaatatttaa aaaattgata tttcctattt tttctccata
    57181 aaatctatag taaataagtt catctctcag tctattttcg tctatataca cacatctttg
    57241 cgttttatca tctattaagg attttgtatt tattatagtt aaatctttaa gagccctact
    57301 tgcactacta aaagaagatg tgtagacttt ttttagtaat tcgtcattca taaatatatc
    57361 ctttctgaaa aattgaatgt aaataaattg ttattaaaaa aaaagagaca gcccgtttaa
    57421 gaagctgtca tatatagggg gatagtagtg tacaaaaatc attgtaatct actatctata
    57481 tattattata cgatactact tttttatatg taaagcatca gttttcgaca tccctatatt
    57541 ttacagttat acaaattgcg tactaagttc aattttattc tttttatttc aacattttat
    57601 catgctacat tctttcagga gcgtgcattc ccaacaattt cagagaattt tctaaagttt
    57661 gttttgttgc taaaactaat gcaagtcttg cttttcttat ttccaaattt tctactaaaa
    57721 ttggattgtc atgataaaat ttattaaacg cttgagctaa atctagcata aatctagtca
    57781 ctatatgtgg ctcatttttc tttagagcaa gtaaaatatt cttattgaat gattctataa
    57841 ctctaagaac ttctgcacta tcttcatcag ctaatagact ataatctata tcagaagtca
    57901 cttctacttc tgcttttctt aaaactgcac agcatctagc atgtgtatac tgaacatatg
    57961 gtccagtctc accatcaaaa ctaagcgttc tttcccaaga gaaggtatag tctttaattc
    58021 tactattaga taactcttgg aatactactg ccccaacacc tacttgctta gatatttcat
    58081 ccacattttt agcatttggg tttttagcta gtataatttc cttagtttta tctatagctt
    58141 gatttaaagc atcttctaaa aatactactc ttccttttct agtcgacata gtaccttctt
    58201 caagtgcaac cataccaaat ccaacatgaa ttaaatcttt tgcccaatca tatcccataa
    58261 gctcaattac cttaaaccat tgttggaaat gtaagttttg ttgagaacca actacatata
    58321 tacacttgtc aaaatcataa gtttcttttc tatatattgc agcagctaaa tctcttgtca
    58381 tatataacgt tgagccatca ttcttagtaa taagtgctgg tggcatttta tactcttcta
    58441 aatcaacaat tcttgctcct ttagactctt ttaaaagatt tttctcttct aatagttcga
    58501 taactctgtt cattttatca gaataaaaac tctctcctgc taaagaatca aattctatat
    58561 ctaaaagttt atacactctg ttaaactctt ttaaactctc atttctaaac cattgccata
    58621 attcttgtgc ttcttcgtca ccattttcta atttattaaa ccatgctctt gcttcatctt
    58681 ccatttctgg gtgttgttca gcttcatcat ggaatcttac gtataatttt agtaattctg
    58741 gaattggatt agactctact acttcttttt ctccccactt tttaaaggcc actattaact
    58801 taccaaactg agttccatag tcacctaaat gatttattct tatagtcttg tatccttgcg
    58861 aatcatatat cttatataaa gcattaccta taactgtagt tcttatgtgc cctatatgga
    58921 aaggttttgc tatatttgga gaagaatatt caactattac agttttatct tttccaaaat
    58981 cactatgtcc gtaattttct ttttcatcta aaactttttt aattacagtt tctgctaatt
    59041 gagatttatt tacaaagaaa tttacatatc cgcctaattg tattactttt gttatctctc
    59101 cacttggttc tatactttcc gccaattcac ttgctatcat gtttggagct tttctaaaca
    59161 ctttggctaa tttaaagcat ggaaaagcat agtcccccat atccttattt ggtggaactt
    59221 ctataagtgc ctctatctct tctttcgata aatcttctat tttttcttta aggcaatttg
    59281 atattgccac cttaaaatct tgcattctgt tgctcctctc tacattgttc ctggtttata
    59341 ttgtgcttat ctctttatgt taaatcaaat ttcgtgtttt ttcaagtatt tcattacagt
    59401 gtaaaacact ttagtaatta tgttttctgt atatattaaa aatactataa ttgcagtttt
    59461 taatcacact attattgatt ttttataaga cttttttcta ttttattgtt tcttgtacta
    59521 tccagttgac tttatatact ttttttaatc ttttatctat tttcatacgt caatgctaat
    59581 tttatatact tttcttttaa tcttttatta atttttatac atcaatgtta actttatata
    59641 agttttttta atcttttatc tgttttcata catcaatgtc agctttatat acttttttta
    59701 cttttttatc tatttttata catcaatatt agctttatat acttttttta atcttttatc
    59761 tattttctat aaatcttttt cactcttaac ttttattcct tcttcttcta atagccttgc
    59821 tgttatacct ttccctggta tctttttacc tgaaaaacta ccatcatata ttagattaca
    59881 tccacaagag gggctaccct cttttagtat tgcttcgcta catacatata aatttgctat
    59941 ttttagagtt tcattagccc ctcttacaaa gttttctgtt acatccttat tatctttagt
    60001 aattactttt ccatcaacta tctcagcagg tggtcttggt gtagatagac cacctaactg
    60061 ctctgggcat acaagtgtaa attctttgcc ttttaaatat tccttgactt tttcattatc
    60121 attattatcg ccactatatt tacaatttat tcctattaaa catgcagata ccaatatcat
    60181 aaaaatgtgc tcctatacaa attcttaata tattctcata caaattacta atgtattctt
    60241 atacaaatta ttttaattta acaattgtta ctcctgctcc accttctcca tattgaccac
    60301 ctctttgtga ttttacatgt ctatttcttc ttaaaatgtc ttgtagccct gcttttaata
    60361 ctcctgtacc tattccatgt attactgtta cagactctaa acctgccaca tatgcatcat
    60421 caagatactt ttctacttcc attatagctt cttctaggtt taaccctcta aggtcaactt
    60481 cattttttac actaccagat tttgacctta taatgtttct cgttgattta gttacatttg
    60541 ttgaaacatc tttgcgtgtt ttttgtaaag acttaaaagg tagagtcatc ttcattatac
    60601 caatttgcac tactgcttct tttctctttt tatctactga aactacacta ccattttgat
    60661 ttaaagttat taccttaact tcttcacctg gctttaagtc ttttatctcc ttatttgata
    60721 cctttggaac tatcatactt tttactgttg gctgaagact tcccatagag ctggtcaatt
    60781 cttttctaag ttcttctatc ttacgattct tttcttttga agctctttct tgttcaagac
    60841 ttctaagttc ttttattata atatctactt cttctttagc ttgtcttata attgaaaatg
    60901 cttctgattt agctttttca atcatcttat ctctttgact gaccaatttt tcaagctttt
    60961 cgtcatactc tactttcagt ttttcaatct cttcttttaa tctttcagct tcttctctat
    61021 cttctactgc tttgattcta ttcttttcaa cattctgtaa cacatcttct aaagctatgt
    61081 tttctgtatt tatatattct ttagcacgtg aaatcacata atcacttagc ccaagttttc
    61141 tagaaatctc aaacgcattt gattttccgg gaacacctat aagtaactta tatgttgggc
    61201 ttaaagtttc tatatcaaat tcaactgctg cattttctac acctggttta gtaagagcat
    61261 aatttttaag ctcactatag tgagtggtag ctatacattt agctcctaca gaatttatat
    61321 cttctaatac tgctattgca agggcagctc cttcaacagg gtctgttccc gctcctaact
    61381 cgtcaaatat aactaaagag tctgctgtta cgttttgtaa tatagatact atattcgtca
    61441 tatgagatga aaatgttgat agactctgtt caatactctg ctcatctcct atatctgcaa
    61501 atacattatc atatacacac atactacttc cataatcagc aggtatatga agtccacttt
    61561 gtgtcataag tgcaaataga cctacagttt ttattgtaac agtcttacca cctgtgtttg
    61621 gacctgttat caccaatgta tggaagtctc ttcctaaata aattgtattt gctactacct
    61681 tctttttatc cagcagtgga tgtcttccat tttttatgtt taaatattta tcctcattta
    61741 aagttggttc tattcctctc atctgtatag aaagttttcc ctttgaaaat gcaaagtcca
    61801 atcttccaag tatctcttga ttagaaatta agtcttcact aacttctcca accatagcag
    61861 aaagctctga taaaattctt tctatttctt cttgctcacc tagttttaac tgtctcaatt
    61921 cattgttcat ctctactata gtcattggct ctataaaaag tgtcgcacca gaagatgact
    61981 ggtcatgcac tataccagct acttgcgacc tatattcaga ttttacaggt actacaaatc
    62041 tatcacctct tagagaaatt attgcatctt gtaagtactt ttgataagta gttgaactta
    62101 ttattgaatt taattttgac ctaatggatt gatttttttg ggctattctt cttctgatat
    62161 ctctaagtgt acttgaagca ttgtcagata tttctacttc actaattata gcattgtata
    62221 tctggtcttc tatgtccttg tatacatata gagaatttga tagagattgt attattggat
    62281 aattaaaatc ttcttcatca ctactagata agctatttct taatcttcta gccactctta
    62341 aggtatctgc tatcataatc agacttcctg ggtcaagaga agcacctata taagctctct
    62401 ttaccttatc ttctatatca tgaatacctt ccaaccctac tgaacctctc tttataataa
    62461 ttgattgagc ttcactagtt tcttctagca tagatttcac ttctacaaaa tcagtatttg
    62521 gtactaaatt ttctatatat tttagaccta aagaagatga ggctttcttc tttaacaaat
    62581 ctattatttt attgtattct agaactctta acgatttctc attcattttc tatattcacc
    62641 atcctcgata ttttaacttt tttatttaat tttaaaaatg tatgttttca agcatttcca
    62701 ataaaaactg caagttttat ttctttttca tttctaaaat tattatattt tttctctttt
    62761 agatatattt tacacatatt ttgtattata ctatgtatgt agctatctat atattataca
    62821 taaacatgct ttatttgtaa tataatctgt taaaaaatct tatttaatat ttttaaagga
    62881 gtttatttta gcttataaaa aaaaatagct acttatatag ataaattaag gaggaacatg
    62941 agtcatggga aacgtattag aaggattaaa accagaaagt gtttttaaaa actttgagaa
    63001 aatatctcaa attcctagag gttctggaaa tgaaaaaggc ataagtgatt ttttacttag
    63061 ctttggtaaa aatttaggtc ttgaaactat tcaggatgaa agcttaaaca taataataag
    63121 aaagcctgct acaaaaggat atgaaaattg tccaggtgta gttcttcaag gacatatgga
    63181 tatggtttgc gaaaaagaaa agaatgttga acatgatttt cttaaagacc ctataaaatt
    63241 aagaattgat ggtgacatga tatatgctac tggaactact ctaggagctg acaatggtat
    63301 agctgttgct atgggtatgg ctatattaga agataatact ttagagcatc ctgcactaga
    63361 agttttagtt actgttaatg aagaagatgg tatgaatggt gcagatgcac tagaccctag
    63421 cttaattaaa ggtcaatata tcctaaatat ggactccgag gaggaaggat acttattagt
    63481 tagctgtgct ggtggtaaaa cttgtgttgt tagtttacct gttgaataca aggaagttaa
    63541 aggtgacaaa caaggattat tagttgaggt tactggacta ttaggtggac actctggtat
    63601 ggaaattgtt ttacaaagag caaatgctaa caaagcaata gctagagtat taagtgtatt
    63661 gaatgttgat tatgaattag cttctgttga tggtggtact aagcacaatg ctatacctcg
    63721 tgaagctaaa tgtgtaatag ctgttaataa agctgatgtt gaatctgcta aaaaacaaat
    63781 aaatgacatt ttaactgcat ttaaacatga gtttactact tctgaccctg gcatgactta
    63841 ctcagtagct gaaacttctg tagacaaagt tcttactaaa gattgtaaag aaaaagttgt
    63901 tcaaatgtct tgcttaactc ctcatggagt tcaatcagta agtcttgata tagaaggatt
    63961 agttgaaagt tctactaact tcgctataat cgaaactaaa gaatctacta ttgaattttt
    64021 aacttctgtt agaagttctg ttatgtctat tagagatgaa atcgctgata gaataagact
    64081 tttggctcaa gctttaggtg ctaattacga ccttatagct caatacccag cttgggaatt
    64141 taaaaaaggc tcaaaattag aaaaaatatg cagtgaaact tatgagaaat taactggtaa
    64201 agttcctact gttatggctc tacatgctgg tcttgagtgt ggattattac ttgataaact
    64261 tcctcatgct gaagctatct ctataggacc agatatgttt gatgttcata ctccaaatga
    64321 acatgttagt atcccttctg tagctaatgt ttgggattat gttattgaaa tattaaaatc
    64381 tatgaaccaa tattaaattt aagttttgat tctaagtaga ttttaatttt aagtaatcta
    64441 tataaaatta actctgtaaa ttaatactac tgttagtata atatttactt tcaatattaa
    64501 cttatagaaa taaagcctaa tgatagataa taacatgtat cattaggctt tattgtaatt
    64561 taaatattat taagctttat tctgttttaa aattaattct tatactattt taaatctatt
    64621 tcttccttgt ctcttagaat cataaagagc attatctgct atttgataca gttcatcata
    64681 ctcttgacca ggctttgcta taactacccc catactaata gataaacttt ctccatttgg
    64741 caacttaatg agatgaatat gattgtatac atcattacat ttattaataa gttcttcctt
    64801 atttattata tcattgatat aaacactaaa ttcatctcca cccaaacgac ctactatatc
    64861 attttttgca aaactttcat caagtacctt tgcaacatca ataagtactt tatctcctaa
    64921 caagtgacca taagtatcat taatcgactt aaaataatca atatctataa tcaataaagc
    64981 accatttttt tcagttgata aattcaacaa attttgtgca gttaattttc taatatatgc
    65041 tgcattataa atattggtta aactatccct ttgagcctta tctaacaatc tattcttttc
    65101 ctctttttca gaatcaatat tacatatttt cccgattaca tacattggta tttttctatc
    65161 attataaatt atttttgaag taactctaat ccaatgaaaa gtatcatcaa gcataataga
    65221 atacatttca gttgttccat tttcttgtga ttttattaca tcaaaaaact ttttattata
    65281 ttctttcctt attttatctc tttcattttc tatattgcca ttttcacttt ccttatcatt
    65341 tttatccaaa ccataataag tctcaatacc cttttctggc atagaaatta tcaatttatc
    65401 ttgcttataa tcatactcaa aaaagtattc acttgtcatt tcatacaact gagtatgttt
    65461 tttgagttct aaagatatct tctcgttcat acttgtacga gtatgcaaac caaatgccat
    65521 aaatccaata atacaaatta ataaactggc tacaataaaa atagtctcaa ttggattctg
    65581 ttgcataata taaagcaacg agaagtcttg tctatatgta gtattttggt agacaattga
    65641 ttgcattttt tctgatgaaa tacttataat agctttatta aatatattca ataattcttg
    65701 tttatctttt ttaattatac caaaacaaat actctttgct ttataagttt gaggaactag
    65761 acgcacattt ttatacttag gttgattcat atagtactgc atagaataac cttcgccata
    65821 agtgtaatct gcatagcctt tattaacagc ttctatacac tcttctaaat tatcatacca
    65881 aactatattc tcttcaaact gaccataata attaatacct ttggctagag ctacacgttt
    65941 tccatctaaa ctattctcat ttaatttatt attaatcatc atagtatatt gagtagaaag
    66001 aaaaggccga gacataacta tattatgttc acgagagtat tcataatcat aaatcattcc
    66061 tgctacaata tcaatttcac gctttttagt catgttttct aaatcttctt gagattttac
    66121 aggcacaagt tcaaattcta agcctgtttt atcacatata tgatttaaca aatcaattga
    66181 tatacctctt aattcacctg tatctttatc tatattttga aatggtggtt tgtttaaaag
    66241 tactcctact tttaattttt ctgtctcttt aatgtaatca gtttcttcat cagataaaaa
    66301 catttgattg ttctctggtg taaagtattt ttcatataaa gtagttgaaa aatatgggtc
    66361 tttctgttca atattattaa ttgctgagtt aagcttttga gttaaatttg tactaccttt
    66421 aggagtaatg aaataaaatg gttttgatga aaattttgct acagtacgta caccttctag
    66481 tgggttcata ctaacattaa gaagtacatc tgctttacca ctctttagtg cttctagttg
    66541 ctcatcattt gttttacaat ataccaattc aggtgacata agattcattt tacaatactc
    66601 atctaactct ttaagtctag tatcagaatt ttctattaca gcaatacgga tttttttcac
    66661 atcttgtgaa ctcattatgt tatcaatatc tgtattttca tataatgctt gtagtactgt
    66721 atttgctact ccataactat ttcctgcata attatatatt ttttgcattg gctcattgta
    66781 taacatacct cccattatat caatttcacc attttctaac atcttcatta attttgtaat
    66841 agattcattt atctctccag gaacttgaac aaattcataa ttccatccag tatactgtgc
    66901 aatttctagt aaatattcat atgtataccc aaaatagtta ccttgctcat ctatttcagt
    66961 taaacctttt tgaataggat aagcaacacg aatggtacga ttatcattac ctatagcgtt
    67021 gataccaaaa gaaaatatgc aagaagtgaa tatagatgta attacaataa ttaataaaag
    67081 taattttttt aaattcacta cacaatcctc catatagtta agatttacag tataaattac
    67141 tgcataaact tgtagacatg taaaaataga ttagtatata aaaggatata taaatctact
    67201 tagaaattta aatatcctta atatatacaa tatatttaaa ttataactca tttatatgtc
    67261 tattacaaca aatttaccct gctaaatacc tactctatat cccataattt tacaagttgt
    67321 agtgaagttt aagttctatc tcacctcaaa tttagcagtg tttctattta cagttctttt
    67381 atatttcaca tctggataac ccaatataaa tgaagtgata acagcttcgt tctcgctcat
    67441 tcctaacagt tcttttatct ttggctctac atttgatgcc ataacaaaaa atccattata
    67501 acaaattcct aatccttgag aatatgccat aagttccata ttagatgcag ccagtcctcc
    67561 atctacataa gcacttccac ctagagacat atctcctaca actaccataa gtagtggggc
    67621 atcataaaat aaagaatcat ttccgttctc tttatatctt ttgtacattt tcttaaatgt
    67681 atttttatag atagaacgta cagggtcatt gtcatcagta tctaatgcca aattataaag
    67741 accttgtatt gccagttctt tcacttcttt tagcttttct tttactaata tgtatcttat
    67801 aggctgtcta ttaccacctg ttggtgtgta tctaccagct tccactatgt tttttatttt
    67861 ttcttcttct acctctatat ctttatattg tcttatactt cttctaaatt taataaaatt
    67921 caataacttt tcgggttcta attcaaaact ttcacgattg tattctatta cttcattttt
    67981 atcaaatcct tgcatttcta ttgcatctgt tgggcaaatt gccatacagt gaccacagtt
    68041 aatacagaga atatttttaa cctttgcttt atcatcctta acttttattg catttacaag
    68101 acagtctgat tcacacatcc cacagcctac acatttttct aaatttatgt ctatcattcc
    68161 aaattattcc tccttttaaa aaatttactt tagtataaaa caaatagttg tctaagtcaa
    68221 tttttatttt tttaacaata tactagcctt aactacactt taatggagaa aaatatacat
    68281 aaattggaac ttaaattaga acttattcaa agtaaaagat aaaagaagta gatgtctaaa
    68341 agtgaacttt ttagttaatt agatattctt tattgtatga aatcaagtgg atatttatca
    68401 tttcaacaat aaaaaaggct tacctctatt ttggatatgt ccctgtcaag tagacagact
    68461 aaaaaaaggc tatctttatg cactgagata gccccttttc ccaactacta ttgtttatct
    68521 taatattagt caataaattt aatttgctat aacctgtaag ttacatttta atttgatgta
    68581 actttaaatt acatttttaa gtaatatctt taaattatat tcttaaaata tatcattaaa
    68641 ctacatttta attaatctaa aaactatatc ttaattaatc taagaaactt acattataat
    68701 cttttagttt cccattatca tatacaatct ttgcactaaa gatatttcca gtcttagccc
    68761 aatttaagaa cagcctgtca ccttcccaca tatttaaatc gaatatttta tcattatcaa
    68821 cccaaattaa atttccttct ttacaatcat ttaaatcttt ttcagataat tcaccttcaa
    68881 actcatctga gaaatacaaa aacatatacc aatcttcttc atctttaaat tttggaaaag
    68941 ttatcaaccc tttatatgac aatgatttaa gagtaagacc agtctcttct tttacttctc
    69001 taattacaca ttcttctgga gtctctcctt gctcaaactt tcctccaact cctacatact
    69061 taccttcatg tatatcatct ttctttttat ttctgtacaa catcaaagtc ttgtcatctt
    69121 tttctatata acaaatagtt gtaagtttca tgtatctcgc cttgctttct ctttatattc
    69181 tcaactaatt attttcagca ctttcaagca catcacttat attcttcatt gcattaagag
    69241 aaagctctgc aaattcatca aatggaatcc ctatatcttc tatacttctc attgcatctc
    69301 tatttacatt tgaagcaaat ctcgtttctt tcattctttt aataacagac ttagtcttta
    69361 cactggtaag ttttttatct ggataaacta aagctatagc agttataaac ccagttatag
    69421 ggtctgctgc atatattgct ttttccatta ggctagttct tgtaactccc attccatcat
    69481 gatgaccaag tattgctcta tacatttctt cgtcaccgaa gttttctttt ttaagcagtt
    69541 ctactgttgt tgtagcatgt ccctcacata tttctcctgg ctttcttcca actatatctg
    69601 aatccaaatc atgtaaaaga cctgccactg cccactcttc ttctttttct ggctctagtc
    69661 ttttggctaa ttctctcata acagcttcaa cagcataaca atgttttctc attctatcag
    69721 tttctaaata cttaaataaa atttctaaag cttcttctct cattttcacc aatccccctg
    69781 ttttttcaca tatatgatat ttttatatat taatacacat aaattcaagt ttttatatat
    69841 attcatgtat atttttcatg ttatatctat tctacacctt tatagtagtg tcctgcaact
    69901 gttccaattt catctaattt cttatacaag tctgtagccc tttttccaag tttataatta
    69961 ttactcaata cctcaatgtg agcttcaata acctttttaa ccatctcact atcttcaact
    70021 gtaaaatcta tcctaaatac atctattcca atttcctcta actcatatag attgtccaac
    70081 atacaagtaa ccttcgaatt gtaaattgta cttctacaga atatatcttg tgttatccta
    70141 taacttgcat ccgtaaagtc tcttaaagca taactacttt ccttacattt agcaactctc
    70201 ttgtcctttt tacaatccct aacaactact cccataggac agtattctgt aaccatcata
    70261 ggagcatatc catatattac tgcttcaatt tctacatctg tatattttaa agtttgttta
    70321 atttcattta agtttagttc ttgtgacaaa caaactgtac ttgctccctc ttctttgaag
    70381 tggtttatac tttcactatt gaatgcattt aagtagcaat ctatatttaa gtcttttttc
    70441 ttaaagtatt ccatagagcc ccagttacca atttgaacct tattaattcc ttttatatta
    70501 tccaatatct caaattgctt gtactcttta tttctaacaa tccttggtgc tgaatagatt
    70561 aattttttgt cagtgactgc tgtattagag tggttcttat tcaaagtatc tattttactt
    70621 gtatttgaca aagtatatat gttatttgta tttgaaccca ttagttcttt aggaatacct
    70681 aaagatgaag aagtatataa atccatagaa atacttgaat ctatagaaat acttgagacc
    70741 atttgtaaag cttttgataa tgtatttata tcttcataat agattaaatc tacattataa
    70801 tttaatactg cttctaattg ctccaagttc ttaactttaa ctctaatctt aggaactgta
    70861 tcaagttttt tctgtttatt tactctattt ggctggtatt ttaatctatt cttcttaaat
    70921 tttctatctt ttatctttat tctttcttca tctaaaagct caatacaatc ccttctcatc
    70981 tgatttaaca cacttatagg catacttaca ccttcatcca ggtcaatttc tatctctttt
    71041 aacttatatg gtgtatttcc aagcttttga atttgtgttt ctattttttc tttacttaaa
    71101 gccaccttta tagctttttc aactattttg tctccttcta ccaccgattt atttccacaa
    71161 aaatcactta taaaaagctc tggcttttta cctagtttaa tactcacttt tgcacgtata
    71221 ttagttttta tgaactcttt atcttgctga aatgtagctt gtactctatc catcaattcg
    71281 ctgtcagaag tcttatatat aagctgattt ctctttgctt ctccaacaaa atctaattct
    71341 atcaaatccc ctttatgtgc tattgtagtt atctctccat cctttattat tcttccaata
    71401 gtacctccac ctaagttaat tccatcacct ttcttaagcg tattttctag cattactcta
    71461 agtcttttgt tctttctatt ataatctaaa acttttccaa tatatagccc ttgattatta
    71521 ggtctattag agttcattat atccttacca acttcaccta atatatatcc ttttgtaaac
    71581 tttctattaa atatggtata caaattattt attatttcct cagaaatact tatttttttc
    71641 ttatctacaa attcattaat cgcttctcta tatcctgaaa ccacagtagc tacatactct
    71701 ggctttttca ttctaccttc aatttttaaa gataatacac ctgcttcaat tattttatcc
    71761 aaatcttcta tagtacttaa atctctagga ctcaacaaat aatctccatt actttttact
    71821 acttctcctg tatttatatc tatcaactca tacttttgtc tacatggctg tgcacaccta
    71881 cctctatttc ccgacctatt gcctatcata ctactcataa ggcattgacc cgagtaacat
    71941 acacataaag ctccatgtac aaaaacttct atatctacag ttgtattttc acaaatccat
    72001 tttatctcat caacatttaa ttctcttgct aaaacaactc tatcaaaccc tacactctga
    72061 aggtatttta catcttctaa ggaatgtgct accatttgag tgcttgcatg tagttcaaag
    72121 tcaggtaata gtttttttat aagtcttgcc attcctatat cctgtactat taaagcatca
    72181 atatctatat cgtataaaaa ttttacatac tctacaaaat cttctatttc atactgtttt
    72241 atcaatgtat ttacagtaac aaagacttgc actcccctta tatgagagta tttaacagcc
    72301 tcaatcagct catttctatc aaagttattt gcagatgctc tagcactaaa gtctttacca
    72361 cctaaataca cagcatttgc tccgttttga actgctgctt ttaatgaatc aaaagagcct
    72421 actggtgcaa gtaattctat ttttttcata tttttctcct ctatttatac ttgttaggtt
    72481 aatataatta tatctataac ttaaatattt gtattaaatt tatatatttc ttactatatt
    72541 ttaaattctt caatcaattt atatattagt tatttatatt tggttcattt gagttaacat
    72601 atacattatt tactatattt agtatatttc tattaactta tatattgatt actgtatttt
    72661 aaattcttca attaatttat atactgctta ctaaatttaa aacattttaa ttaatttgta
    72721 cactgtttac tatacttgaa atacttctat taatctatat attgcctact atacttaaga
    72781 cattttaatt aatttataca ctgtttacta tacttgaaat acttctatta atctatatat
    72841 tgcctactat acttaagaca ttttaattaa tttatacact gcttactata cttaaaatac
    72901 ttctattaac ttatacattg cttactatat tttaaattct ttaattaatc tatacaatat
    72961 ttgctatata taaagtatat caaataacag cttcattttt ttgtaaattt acagaaagtt
    73021 aattttcatt aaatgaatca tctttattga taaacataat tccaaagacc actgccaaaa
    73081 taaaaaaaca tattagtatt gatttttcca cgaaaatttt tgtaaaaaaa gttcctaaaa
    73141 tagctccaga tataaagaat ataataatag cataatactg taaactcttt tttatcataa
    73201 aaatattctt agtatgtata taatgaaata aagtttctgt agcacttctt aaatttccag
    73261 tacacattgt cgttgcaaaa ctattcccat ttacttttct aaaactctct acttgcattg
    73321 aacaaataaa agaaatagca acatttacaa acatattaaa tcttcctcta ggaataaatg
    73381 aaacaataag tattgtaatc atttcaatta taatgataac ctgacgccaa tgaatctttg
    73441 tcttattatt tgtaaaatac tttcttatct tctcggctat aaatacacct aacataaatg
    73501 ccaaaatagg aatcaaataa taaaatgatt cctttacatt accttctgct atattaagcc
    73561 caaataaaac tatatttcca gtttgtgcat tagcaaagac tttacctctt accacataag
    73621 tataaatatc caaaaatcct cctgttattg ccaacaaaga acataaaaag aatgattcag
    73681 acatctgact cttgcttgtc atatataaac ctctcgcttt ctaatgatag atacaaaatc
    73741 aaaatcattt tagattctat ttttcattga tataaaaaaa ttatttatat ttaaatattg
    73801 tctatattta tacattattt gtatttatat agcattcata tttatttata tttaaacatt
    73861 atctatat
//
LOCUS       DAYAOO010000007        71558 bp    DNA     linear   BCT 12-OCT-2024
DEFINITION  TPA_asm: Clostridioides difficile isolate ST8-SSI-h139-18
            SAMN40601845-rid21577343.denovo.007, whole genome shotgun sequence.
ACCESSION   DAYAOO010000007 DAYAOO010000000
VERSION     DAYAOO010000007.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN40601845
            Sequence Read Archive: SRR28438827
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 71558)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 71558)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-MAY-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-MAY-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002157583.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002157583.1
            Genome Coverage       :: 163x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/11/2024 16:19:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 4,038
            CDSs (total)                      :: 3,963
            Genes (coding)                    :: 3,930
            CDSs (with protein)               :: 3,930
            Genes (RNA)                       :: 75
            rRNAs                             :: 6, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 60
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 33
            CDSs (without protein)            :: 33
            Pseudo Genes (ambiguous residues) :: 0 of 33
            Pseudo Genes (frameshifted)       :: 7 of 33
            Pseudo Genes (incomplete)         :: 25 of 33
            Pseudo Genes (internal stop)      :: 11 of 33
            Pseudo Genes (multiple problems)  :: 8 of 33
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..71558
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN40601845-rid21577343.denovo.007"
                     /isolate="ST8-SSI-h139-18"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Denmark"
                     /collection_date="2018"
                     /collected_by="Statens Serum Institute"
     gene            complement(<1..161)
                     /locus_tag="ACGI5H_000532"
     CDS             complement(<1..161)
                     /locus_tag="ACGI5H_000532"
                     /inference="COORDINATES: protein motif:HMM:NF024242.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0043565 - sequence-specific DNA binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HFG9696262.1"
                     /translation="MFFSLFKKKSGYTFTNFLSKVRVEKSKKYILKKDLSILDVAVLI
                     GFNSQNYYS"
     gene            454..645
                     /locus_tag="ACGI5H_000533"
     CDS             454..645
                     /locus_tag="ACGI5H_000533"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423633.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9696263.1"
                     /translation="MERLMELIERKFLKDVELLELEDIENVIECKMTQPYNAHYNEYL
                     VKVKNGDEVEEYFVYLKHR"
     gene            complement(734..1546)
                     /locus_tag="ACGI5H_000534"
     CDS             complement(734..1546)
                     /locus_tag="ACGI5H_000534"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430209.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Mrp/NBP35 family ATP-binding protein"
                     /protein_id="HFG9696264.1"
                     /translation="MADCNSCPSKGNCNSQSNCSIENNPNNKFGKIIGVMSGKGGVGK
                     STVTALLANKLNKMGYKVGILDSDITGPSIPRLMGVKNVKAYSDGSYIYPVENSNNIK
                     VMSINLMIDDENEPVVWRGPLLGGVVKQFYTDVLWEELDYLLIDMPPGTGDVALTVMQ
                     SIPISGIVMVSVPQDLVSMIVSKAVNMAKKMNINVLGVIENMSYIQCPDCSKKIKLFE
                     GESTEKFLDDLDLELLGELPMTKEIIDITHNGVTEISDDLDSILTNVVEKIK"
     gene            1968..3119
                     /locus_tag="ACGI5H_000535"
     CDS             1968..3119
                     /locus_tag="ACGI5H_000535"
                     /EC_number="2.3.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004452985.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HFG9696265.1"
                     /translation="MELRPRSAKLEEFDKVIELINYVFRISRNHKPTMMEEFPLLLSK
                     NNIENMIIISEDDKVISDVNYLIQDVSIQGNRLKVAAIGGVCTHPDYEKRGYSSKILD
                     KVEEKMFYDGVDIVIISGTRSLYSRRNCSLVKSFYKYTIKPEDVKIAYEIVEFDETNF
                     EKDNDLDKMIELYNQNSTRFIRTRDEFQKLLHAATIAWGPIGYKKVFIKENNNIIGYL
                     IIRTIKKEDSTVGEVAEIGLNSVNVENILKYVANKFGLEYLNYKVHVKNLKDQLKCNG
                     TKSLDYQQGTMKIINFTKLCDSLRSYFSQYVDFELLKYMEFKQVENKYIIKYKEEELV
                     IENLDKLNKLFFEKNEEQYNEFKHLKNIYEFATKAFPVDFPWTANLNYQ"
     gene            3237..3875
                     /locus_tag="ACGI5H_000536"
     CDS             3237..3875
                     /locus_tag="ACGI5H_000536"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423639.1"
                     /note="Presence of a B(12) (cobalamin)-binding domain
                     implies dependence on cobalamin itself, in one of its
                     several forms, or in some unusual lineages, dependence on
                     a cobalamin-like analog; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology.
                     GO_function: GO:0031419 - cobalamin binding [Evidence
                     IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cobalamin-dependent protein"
                     /protein_id="HFG9696266.1"
                     /translation="MDILDDIAECILNMGVDNIENLVKIAIDKNIDVEDIYEYGLNKG
                     MIGALDKFENKEYYLSEVIVCTDALNKGINLLKGTGKVKKKSKGVILMSVVEGDTHEI
                     GKNIVKVMVEATGYKVIDLGVNRKSEDIIEEAIKNNVDIIGLSSMMTTTMENMKSVID
                     ELNMIEIDKRPKVIIGGGPVSMEFAEEIGADGYSSNAPKAVKLINKLIGGEV"
     gene            3876..4898
                     /locus_tag="ACGI5H_000537"
     CDS             3876..4898
                     /locus_tag="ACGI5H_000537"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893254.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uroporphyrinogen decarboxylase"
                     /protein_id="HFG9696267.1"
                     /translation="MFSDMTLLQYINSEDRGFFLPDMGTNGLFLINKKAYEVYDSVDL
                     QLELAKTMDKYFESDFIYSFCDGITFCETLGLETLRPDYDFPSVLTHTITDRDKLRKL
                     DVPDPYTSGRMPLNIESLSVISKSIKKPLYESIQGPFTLAGQLAGATQLLRCIITDKK
                     FVEELLEFTTELVRRYAVAANKAGAKYISIAEPTSVTLSKDRFDEFIVKNLNKIYNEL
                     DCWKGMHICGDTRELLDNMLSCNIDAVSLDQILDYEEIAPMIPRDIVLIGNLDPIKLL
                     GRSKPDKIRRETLKLLKKMRRYDNFLCDFGCNCLNTTPVENLQAAIKAGRISYKELDR
                     IDIDEL"
     gene            4888..5508
                     /locus_tag="ACGI5H_000538"
     CDS             4888..5508
                     /locus_tag="ACGI5H_000538"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9696268.1"
                     /translation="MNYNSNKNKYLLKDINLDDIFIDKNIVLKFLGYGNRKAPDTISK
                     IVEREIRNINDILDIKIYISEVDINKTPKECKKAFAVLYTIGDKIDIKMNDYMENCNM
                     MAGLALDKIGIVCLDYINEKIKMYLKGKYDSLKISHEIYPGDKDFEVERQKDIYNYVK
                     NKYNSIEIEINDYHQLSPIKSVAMLILMGDEENLESRCSKCPRKCF"
     gene            complement(5632..6318)
                     /locus_tag="ACGI5H_000539"
     CDS             complement(5632..6318)
                     /locus_tag="ACGI5H_000539"
                     /EC_number="3.1.3.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861319.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008253 - 5'-nucleotidase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="YjjG family noncanonical pyrimidine
                     nucleotidase"
                     /protein_id="HFG9696269.1"
                     /translation="MKTYKFIFFDADDTLFDFKKSESHAFKKLLSEFDLEFNFENYIE
                     SYRNISDKLWLDLEKNIITLNELKLLRFELFANKISLDVDSETLSKMYLNFLGECTFL
                     IPGAIDILQYLKKKYTIVIITNGISAVQNKRLENSKIKGYIDGMVVSEELKISKPNPE
                     IFKYALKKFNCHDKSSALIIGDSLTSDVLGGINSGIDTCWLNSNNSINYTNHIPTYEI
                     NTLIELKKLL"
     gene            complement(6332..6877)
                     /locus_tag="ACGI5H_000540"
     CDS             complement(6332..6877)
                     /locus_tag="ACGI5H_000540"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454415.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HFG9696270.1"
                     /translation="MNDLNLGEKIAEVRKKQNLSIRDLAKLADVTPSLLSQIERGLAN
                     PSVNSLKSIASSLNVPLFTFFVSEVDKKNLIVRHDNRKKVILPGSKEVIYEILIPDSS
                     GNLEFAIMDLAPNTSSCVDRITHNGDEIAYVLEGEVKLFMDDDEFTLSKGDSVKVPLG
                     TKHKWQNDSNSESKVIFAVIL"
     gene            7105..8352
                     /locus_tag="ACGI5H_000541"
     CDS             7105..8352
                     /locus_tag="ACGI5H_000541"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728591.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GntP family permease"
                     /protein_id="HFG9696271.1"
                     /translation="MQITTFGAIFGLLIAIILIIKKFQAVYSLMLGAFIGGLVGGANI
                     TQTVDFMANGAMNISPSILRALASGVLAGSLIKTGAVDKISEQIVKIFGEKRALFSIA
                     ISTMVLAGVGVNLDVSIITVAPIGLYIGRKLNYSKLSILLAMLGGGKAGNIISPNPNT
                     IAVADNFSVNLSSVMMANIIPAIIGVVITVILASILINKGNKVQSYEILEQREDLPSL
                     FKSLCGPIIAIFLLFLGNVSPIVIDPMIALPIGGIVTLIVTGNLNNSREYLTFGLSKM
                     QGVCILLLGTGTIAGIIQMSELQQSTIGALQFLNMPQFLLAPVSGILMSLATASSTAG
                     ATIASSTFHDAIINGGLSPISGASIVNAGSSVFEQLPHGSLFHTSAGSINMDIGERFK
                     LIPYEALIGIVMTIISTSIQLVL"
     gene            8439..10433
                     /locus_tag="ACGI5H_000542"
     CDS             8439..10433
                     /locus_tag="ACGI5H_000542"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889695.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transporter substrate-binding domain-containing
                     protein"
                     /protein_id="HFG9696272.1"
                     /translation="MNKKKIVIIGIIYSFLVVFSLTNMYVNMEYNLNVFEYIKKSLPF
                     TEEEKKWLEKHKNLIYSSDQSSPPLRYKGKEDGQYKGIIVDLINSLSIQIGRDFYFKP
                     NNWWKESFVNSIDDSIKFFDLIPSKERANKFIFTDPIYTLSANILKDKKSQDINSYMD
                     LKGKTVAIPEGDYSINFLKQKIQDINILLTPDIKTGVNHLMSGKVDAVVGDEPVLRYY
                     INNYGLSNKYSVLSNPIYTKKAVLAVPKQYEELVSILNKGIFKLQKNGVYKDLKKKWY
                     STYNEVDDILYERGIVPSIYLFIGIILISIYVFYSYTYLLKIEIKRKTEQVIENKKTL
                     EATFNSITDIIMLVDENNNIVESNKVLYDFMGEMSYKIADLISMIKGVIENTFSENTN
                     KTSEIEIHNKILKINTFPVEYKKNNTEYIVVLIKDITNDKIVEAKLLRENKMISIGQL
                     ASGVAHEIRNPLGIIRNNCYLLKDNVTMEEVNDCVKSIESNVDRASNIITNLLNFARI
                     SDDNLEHINIKNFIENIVKLQYKMLQLKNVEIKIDCEHNLICYINGESLKHVFINLIS
                     NSIDAIHQDGKIIIYCYEKNHCLFIDFKDNGEGIKEDVLKDIFNPFYTTKPIGEGTGL
                     GLYITYNEIKKNNGDISVESKLGVGTCFHIKIPLNKEVTI"
     gene            10433..11755
                     /locus_tag="ACGI5H_000543"
     CDS             10433..11755
                     /locus_tag="ACGI5H_000543"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423653.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-54-dependent transcriptional regulator"
                     /protein_id="HFG9696273.1"
                     /translation="MKILLVDDELEYGVVMKKILQKKGYLVDIALSGEEAINIIKKDK
                     NYDLVLSDVMMKNMDGVQLLDRIKSINRDIEVILVTGYGSIENAVDAMKRGALSYFIK
                     SNPIENLLEEVEKVKASKISVSVQKNNFEFTLESKNRDFNNIIKIAKKAACKDVNILI
                     LGESGVGKDILARYIHSISPRKNEIFVPVNCCSFSENLLESELFGHEKGSFTGAVDSR
                     KGRFELSNKGTLFLDEIGDIPLNVQVKLLRTLEDKSIERIGSNKSIKVDFRLICAMNK
                     EPKVEISNGNIREDFFYRISTITITIPPLRKRREDLTTLIEFFLNKYQIEHDKKIHSI
                     DKEVKDFLLNYNYPGNIRELKNIINRLVVLSEEGNLSKDNLNLISNNVYIDDKISIRP
                     LREIRKEFECEYIEKVLSLCGNNISNTAKKLEISRRQLTNKISEYNIK"
     gene            12034..13320
                     /gene="grdG"
                     /locus_tag="ACGI5H_000544"
     CDS             12034..13320
                     /gene="grdG"
                     /locus_tag="ACGI5H_000544"
                     /EC_number="1.21.4.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006807454.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sarcosine reductase complex component B subunit
                     alpha"
                     /protein_id="HFG9696274.1"
                     /translation="MKLELGNIFIKNVEFGEKTEVKDGVLYISSEEIEKIVLEDERIV
                     SVNVELARPGESIRIAPVKDVIEPRVKIGDESKIFPGIINKVKTVGSGRTHVLLGACV
                     VTCGNIVGFQEGVIDMSGPTAKYTPFSKTNNICIVIKAKDGIDTHDYEEAARIAGLKI
                     GAYVGEAGREVEPDEVIVYETKPLLKQVKEYPDLPTVAYVHMLQSQGLLHDTYYYGVD
                     AKQIVPTFMYPTEIMDGAIISGNCVAPCDKVTTFHHLNNPVIHDLYKRHGKDLNFIGV
                     ILTNENVFLVDKERSSDMVAKLIEFLGVDGVLVTEEGYGNPDTDLMMNCRKCSEVGAN
                     VVLITDEFPGKDGKSQSIADATKEADAVVSCGQGNLVVHFPAMEKIIGTLDYVEMMIG
                     GYKGCLNEDGSMDAELQIIIASTIANGYNHLTARYY"
     gene            13406..14713
                     /gene="grdF"
                     /locus_tag="ACGI5H_000545"
     CDS             13406..14713
                     /gene="grdF"
                     /locus_tag="ACGI5H_000545"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_082007859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_except=(pos:14453..14455,aa:Sec)
                     /transl_table=11
                     /product="sarcosine reductase complex component B subunit
                     beta"
                     /protein_id="HFG9696275.1"
                     /translation="MSKIRVVHYINNFFAGIGGEEKADIPPEKRAGVVGPGIAFQSQF
                     NDDAEIISTVICGDTYFGENIESATQELLKMIKEESPDLFIAGPAFNAGRYGVACGTI
                     CKAVEEELNIPVITGMYKENPGVDMFKLDLHIVSTGNSAASLRKVVPIMTKLGLKLVR
                     GEEIGPPEEEGYIMRGIRKNFFHELRGSERAIDMLVKKMKGESFETEYPMPEFDRVTP
                     MKPVKDLSKIKLALVTSGGIVPIDNPDKIESSSATKYGIYDLTDMDSMSNKEFTTIHG
                     GYDRAYVLENPNLVVPLDVVRELEKEGVIGELVDYFITTTGTGTSVGNSKRFGEEFSK
                     KLLEDDVDAVILTSTUGTCTRCGATMVKEIERAGIAVVHICTVVPISLTIGANRIVPA
                     VGIPYPLGNPMLGEEESKKIRKNIVLKALNALTEDIEEQTVFE"
     gene            15005..15721
                     /locus_tag="ACGI5H_000546"
     CDS             15005..15721
                     /locus_tag="ACGI5H_000546"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454401.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LytR/AlgR family response regulator
                     transcription factor"
                     /protein_id="HFG9696276.1"
                     /translation="MYILISIAICDDESYMLNHLKENIELYMKQKNLLYNIELFNKVE
                     DLLCNHEKFNIVFLDIQMEEINGMQAARKLRSYGNECFIIFVTVLNEFVFDAFEVDAI
                     NYLIKPLSNEKLYKTLDKIVTKLDDNESNYITIQKGYSYWKLKLADILYCEVIKRKIY
                     VHLKKETVDYYETIENLERSLPTNFFRCHRSYIINLQYVYGYENGNAVMESGDRIPVS
                     RLRQQIFSKVMLEFMKNRRI"
     gene            15723..17081
                     /locus_tag="ACGI5H_000547"
     CDS             15723..17081
                     /locus_tag="ACGI5H_000547"
                     /EC_number="2.7.13.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896878.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000155 - phosphorelay sensor kinase
                     activity [Evidence IEA];
                     GO_function: GO:0004673 - protein histidine kinase
                     activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0007165 - signal transduction [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HFG9696277.1"
                     /translation="MINLFSSDLFLKYSFFFSFIVYRILMVIVQYYFLINFTNFNSKF
                     WCFILYSIISIFLIIINTYFNLYNLFSSQILFFLMTFLFVKYIIKQSTVLSIVSTLLV
                     YLIEQLVYGFTAPLNYLIFTSDINTDIYKFDINMGLSSLITIIIAGFIYWYSSKKFNI
                     KVMNFDKYIAILMIPLLLIILFMQSFEYSSNINIDTSLGIVKLLLNTSITEEIQAFLF
                     SIIGTICVFFSLFTFKKLIQALEDDKERAIMNQQIHAQKNYIEEAKSRLSQTISFRHD
                     FNNHLAIVNGLLKKDQILKAQDYLNKLEKVTSDLSFSCNTQNIVIDALFNNKLSIAKQ
                     LGIEVDCEVIIPQSTNMNDFDLCIVFANAIDNAIKACRVVDKQNRYLKLSTKLEGGFF
                     MIEIKNSYNPINNYTSGSGIGLLNIKEIAKKYQGAISIDKTSDYFQINVLLVISLHCA
                     SI"
     gene            17171..17605
                     /locus_tag="ACGI5H_000548"
     CDS             17171..17605
                     /locus_tag="ACGI5H_000548"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896879.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9696278.1"
                     /translation="MKVGNINGQAPITNGLDSCQSEVQGLEQKKKALQDEIEKVRSDK
                     SIDGETAKLKIEALKKEMEEIENKIQELKGNKGKKTNKEENNVSEVNNNLLERKKEPS
                     NNENVKQLYDVFERSNVDEQWDNTYRVLQDDKNLKVKFNRPI"
     gene            complement(17868..18104)
                     /locus_tag="ACGI5H_000549"
     CDS             complement(17868..18104)
                     /locus_tag="ACGI5H_000549"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430229.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9696279.1"
                     /translation="MLLTHIYFNGQFKQTIELYKQAFNATVKTLIEDSCYLLIVHNEI
                     VIHNKFLILNDFGNKNGVSISEGYQPTYKIQTAS"
     gene            complement(18260..18484)
                     /locus_tag="ACGI5H_000550"
     CDS             complement(18260..18484)
                     /locus_tag="ACGI5H_000550"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423664.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ferrous iron transport protein A"
                     /protein_id="HFG9696280.1"
                     /translation="MTVYNLKLGQKGIIDNIAGNEKLMKRLLALGLIDGTEVEVKKIA
                     PLNDPIVIRFRGFDLAIRKSDAKNINLKNN"
     gene            complement(18581..19834)
                     /locus_tag="ACGI5H_000551"
     CDS             complement(18581..19834)
                     /locus_tag="ACGI5H_000551"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902743.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sodium/glutamate symporter"
                     /protein_id="HFG9696281.1"
                     /translation="MITLSFDIVQTLTLSIFFFLIGNLLKNKVNFLNNFCIPAPVIGG
                     LLFCFLNLFFKYFNIADISISGNLMPNFITFFFTTIGLEISINLIKKGGSVLFRYWIL
                     CGVLAFCQNILAITISKIIKLEPLLGLMCGNVSMEGGHGYSAAFGLTIENLGIEGAVG
                     VGLSAATIGLIMGGILGCPVAKFLINKYKLKPSSNIDLSIPRYNRNLKRFGSKFFRNK
                     NRIKNNNFSETITPSVFLEQVLLIFICINTGEIISRCFYITFNILLPSVVTCMFSAVI
                     FRNLNDKINILELNFKLIDFLKELSLGIFLTLSLMNIDLFELSTLLPPILLIVTFQVI
                     FIILFSIFICFRVLGKDFDSAIIISGLIGHGIGATPNALANMSSLTQKYGDSPKAFLV
                     VPLVSGFLLDAISIPCILFFINILT"
     gene            20094..21083
                     /gene="add"
                     /locus_tag="ACGI5H_000552"
     CDS             20094..21083
                     /gene="add"
                     /locus_tag="ACGI5H_000552"
                     /EC_number="3.5.4.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454392.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004000 - adenosine deaminase activity
                     [Evidence IEA];
                     GO_function: GO:0019239 - deaminase activity [Evidence
                     IEA];
                     GO_process: GO:0043101 - purine-containing compound
                     salvage [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="adenosine deaminase"
                     /protein_id="HFG9696282.1"
                     /translation="MFENLPKIDLHCHLDGSVRVETMLDIAIKEKIDLPSNNMDEIKK
                     LAKVSFNCTSLDEYLEKFDLPLKVMQSKENLKRITFELLEDASRENVKYIEIRFAPLL
                     HTQKGMSVKNIIEGIIEGIREAESIYDIKGNLILGCMRTMTSKEALLVIEEGKSFVNK
                     GVVAVDLCGPEKEGFCKEYKDVFKLAREYGYKVTIHAGEAASGENVLDAINILKADRI
                     GHGVKIKDHKKAYNLVKDKKILLELCPTSNVQTKTVDSYEAHPFYTFYKDNLHVSINT
                     DNRTVSDINLSSELNVIFDTFKLGLEDYKIIYRNAVEASFADKETKEYLNSLI"
     gene            21155..21895
                     /locus_tag="ACGI5H_000553"
     CDS             21155..21895
                     /locus_tag="ACGI5H_000553"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454391.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EcsC family protein"
                     /protein_id="HFG9696283.1"
                     /translation="MKDYEDVVYIKLVKKELEEWKKNILKKPSIFDKASKGIQNKFNG
                     VLPDKYHEIITSSIKVMTKTVLFGYKYATKPSLRNMSLEEREKLVLEKAKTYKTTAMI
                     EGAGTGAGGILLGLSDFPLLLGIKVKFLYDVASIYGYDVKDYRERIYILNILQLAFSS
                     QQHINKTFKLMNNWDEYVNSLPEDINDFDWRTFQQEYRDYLDLAKFLQLMPGIGAFVG
                     FYVNGKLIDKLCETAVSAYRLRIRELKL"
     gene            22095..23246
                     /locus_tag="ACGI5H_000554"
     CDS             22095..23246
                     /locus_tag="ACGI5H_000554"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454390.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="double-cubane-cluster-containing anaerobic
                     reductase"
                     /protein_id="HFG9696284.1"
                     /translation="MTNLPKQFDSFNEARQKGFINAKELKESGKKMVGVFCTFTPVEI
                     PMAAGATVVGVCGVSEEPIPDAERVLPRNLCPLIKSSYGHAITDTCPYFYFSDLLIGE
                     TTCDGKKKMYEELAKVKPTYVMHLPNTSKGEFAYKLWKDEMIRLKEEVEKSLGVTITE
                     EDIRTAIKDKNEERELLKEFYALGKLQPSALTGLELHNVLYQAGFKFDRAELKHSLRK
                     VIDDMKERYEKGECPVQKDKPRILITGSPIGGISEKIVKTLEDAGASVVAYELCGAIR
                     SNDLLVDEEIEDVYDALTQKYINIGCSCMMNNDNRIELLDRIIDEYNVDAVIDVVLQA
                     CHTFNIESYRIREFVTKEKNKPFMSLETDYSKSDTEQLRTRFEAFVEML"
     gene            23271..24026
                     /locus_tag="ACGI5H_000555"
     CDS             23271..24026
                     /locus_tag="ACGI5H_000555"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430240.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008047 - enzyme activator activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="acyl-CoA dehydratase activase"
                     /protein_id="HFG9696285.1"
                     /translation="MFSIGVDSGSVATKGVLFDGEKIIKKIIIPTGWSPKSTSKQVYE
                     LLSSEIDKKDIKKVVGTGYGRGVMDFADKKVTEITCHTRGIYFLNKNIRTILDVGGQD
                     SKVINLDRDGNVFNFIMNDKCAAGTGRFLEITSNLLGSDIESIDTLAKGYEPVNISSM
                     CTVFAESEIVSLLAQNISTGEVAAGILKSIANKSTSMLARGEVIDEVAFTGGLAKSKE
                     LVKMIEEILGKKIFIAEDTQIIGALGAAVIGFR"
     gene            24218..26605
                     /locus_tag="ACGI5H_000556"
     CDS             24218..26605
                     /locus_tag="ACGI5H_000556"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861325.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall-binding cysteine protease Cwp13"
                     /protein_id="HFG9696286.1"
                     /translation="MKKFTSKKVTRFVALFLISILVMSTIPVSADNSNTLNQIKKAEY
                     SETYKQYLNDAKNGRTEKYNGIIPNPYQLEGTQIQSKGRTAPTSYDPRKLGLMTSIKN
                     QEDLGICWDFAAMATLESFLKLNNYGDYDLSEEHLRWWASDGEYGWSVNDMNGALNYE
                     AMGYLTSWSGPKLEKDIPYNGRVSKAQGAKKPTNMNTAPTVFNVTDAVCVSNDINSTK
                     NAILQYGAVTSGYYEDIKYQSDDQNSYYCPTKSFNTNHAISIVGWDDNYSKDNFNANI
                     RPSKNGAWLIKNSWGDYNSEGGYFWISYEDKTLMSDIDNFSIKGGKKPNDDEKMYQHD
                     YASIVPLISKKITAANVFDFNRGDETLKSVMFLTESIGAKYEVYYAPVVNGIPQENNM
                     KKLKEGTAQYSGYITVPIDSFDIPEGKGAIVVSIEGKNGESTIGSESNVPGYDTFKAK
                     ANLGESYIIDNTGKFFDINRDSNFYPCNFTIKAVTEKSSGESIPNESLIGSDRYETAI
                     KVSQNGFNSSENVVLVNGSSIVDALAATPFTSAINSPILLTQKEALNSKTKAEIQRLG
                     AKKVYLIGGENSISKEIEQQLKSLNISIERISGSDRYKTSLLLAQKLNGIKNVSQIAV
                     VNGVKGLADAISVGAAAAENNIPIILANEKSELQGADEFLNSLNIEKSYIIGGTASLS
                     NNLESKLKNPTRLSGSSRDETNSKIIDNFYKKDTLKNAFVVKNGIKNQNDLIDGLAVG
                     PLGAKTGSPVILVGDKLADSQKEVLKNKTLEKVTQVGGGANKNAFKELVKLKSAK"
     gene            complement(26836..27069)
                     /locus_tag="ACGI5H_000557"
     CDS             complement(26836..27069)
                     /locus_tag="ACGI5H_000557"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430242.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATPase"
                     /protein_id="HFG9696287.1"
                     /translation="MATTTKNRFYDYVQENLNKYVEVHSYFSSCPLYGEIIEADSLSI
                     TLCSRYIDESNPTLNETYTLYLPLSSIISIRTL"
     gene            27358..27948
                     /locus_tag="ACGI5H_000558"
     CDS             27358..27948
                     /locus_tag="ACGI5H_000558"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454386.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HFG9696288.1"
                     /translation="MPKSYSDKEREYIIKRLKEEARLCMEQYGIRKTTVDELVKRVKI
                     PKGTFYLFFQSKELLFFEVLRDIHDSIQKEILYEINRVDESITCEQLTDIFMKFYRMV
                     DSTSILNLMINGEFEILVRKLPDSIIEEHFRHDDFEIGEIISCIPNAKNKDIESFSGA
                     FRAVFLTMLYKREVGSNCFEDALRLMINGLVIQLME"
     gene            28062..28907
                     /locus_tag="ACGI5H_000559"
     CDS             28062..28907
                     /locus_tag="ACGI5H_000559"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892238.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HFG9696289.1"
                     /translation="MIKVDDLSFSYTERDFLQNINFGVGKGEILGFLGPSGAGKSTLQ
                     KILIGMITNYGGSVIVNGVESKRHSNKFYENIGVDFEFPSLYEKLTAIENLKYFGSLY
                     SKKLLSIDELLKSVGLENEANKRVSEYSKGMKSRLNFIKALLHNPDILFLDEPTSGLD
                     PSNSKVMKDIILSEKSKGKTIILTTHNMLDATELCDRVAFIVNGKISALDTPHNLIMS
                     KGAIKVRYTYFDNGEKTSECFLNNTANDKNLNMLIEKNKLLSIHSSEPTLNDIFIEIT
                     GRNLQ"
     gene            28904..29587
                     /locus_tag="ACGI5H_000560"
     CDS             28904..29587
                     /locus_tag="ACGI5H_000560"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902753.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HFG9696290.1"
                     /translation="MRLKNLILGDIKFQFKYGFYFLYLFLSIIYICIINVFPTFMREK
                     IAIIMIYSDPAAMGLFFMGAIVLLEKSQRVLNSLAVSPVKVSEYILSKVISLGVISSI
                     VAMFIAITLNLDNIIISTIGTFFSSIIFSLLGLILASKASSLNQFIVLSIPIEIICFI
                     PPILNVLLDTKSYANLYPFNICISLISGDKNFIMINILILISIIIIIYFITYYFICSS
                     WKKVGGVKL"
     gene            29584..30300
                     /locus_tag="ACGI5H_000561"
     CDS             29584..30300
                     /locus_tag="ACGI5H_000561"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902755.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HFG9696291.1"
                     /translation="MIKIINAFKQEFEQIKRDAMLFIVCVSPILCGVFIKFGIPLIQN
                     ISLNKFYYQLNLEPYFLMFDLLLAFITPFMFFFASTMVILGEIDDSISRYLIVTPLGK
                     TGYLISRFGIPGILAFIITMILLIFFSLTKISFLLNLSISLLVLLQGIIISILVISLS
                     SNKLEGMVITKFSGVFMMGILAPFFILNKAQYILFFLPTFWISKAFKEDNYVYMFISI
                     VISLIWILLLFKKFSKKIVK"
     gene            30397..30660
                     /locus_tag="ACGI5H_000562"
     CDS             30397..30660
                     /locus_tag="ACGI5H_000562"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423694.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HFG9696292.1"
                     /translation="MKNKIKILREKLGLTQEQLGRLVGTSRQAINAIETGKNEPSIWL
                     AYDISRIFNEPIESVFLFEESERKSRAQISRGEYYGYKKDKNI"
     gene            30632..31087
                     /gene="def"
                     /locus_tag="ACGI5H_000563"
     CDS             30632..31087
                     /gene="def"
                     /locus_tag="ACGI5H_000563"
                     /EC_number="3.5.1.88"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728601.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042586 - peptide deformylase activity
                     [Evidence IEA];
                     GO_process: GO:0036211 - protein modification process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="peptide deformylase"
                     /protein_id="HFG9696293.1"
                     /translation="MAIRKIRTFDDEILRKKSKYVENVDNKIREILNDMAETMYNTPN
                     GGGLAACQVGVLKRLVVIDLGEGLIKLVNPEIIKQEGEQIVVEGCLSFPEVWGKLKRP
                     KKVTVQALNEYGEKIEIKGSGFMAKCLCHEIDHLNGIVFTDKIIEHVKL"
     gene            31139..31600
                     /locus_tag="ACGI5H_000564"
     CDS             31139..31600
                     /locus_tag="ACGI5H_000564"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454381.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyrimidine dimer DNA glycosylase/endonuclease V"
                     /protein_id="HFG9696294.1"
                     /translation="MRLWHKDLIDVLPKNQLVSQWRELLAIKGSIDKKGTPNHLLVNK
                     VLNYSIDEFKFYTKIVHDEMLKRNYKPNELKYTSILKWKNRNFANDISNEHSLNLENL
                     YDDWHNKMYLKQCLYNLEEKATCGGIPINEWNILLCKYSKDYELWSGNIMF"
     gene            31650..32552
                     /locus_tag="ACGI5H_000565"
     CDS             31650..32552
                     /locus_tag="ACGI5H_000565"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893277.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="radical SAM protein"
                     /protein_id="HFG9696295.1"
                     /translation="MYNKIKYIPINCEIACNKLKRSMPYKWDLNIYRGCEHGCKYCYA
                     IYSHKYINSNNYFEEIYVKTNIVEKLERQLKSSKWKKEVINIGGVTDSYQPIEADYKI
                     MPEILNLLIKYKTPAIISTKSDLILRDYDLIDKLSRITYINVASTITTVNEDTQRLIE
                     PNGVDSMRRFKMLKEFRKTNASVGLHIMPIIPYITDDFDNINSLFRHAKECNVHYVLP
                     GTLYLRGITRGVFFDFVKKEFPELFDKLSILYSEGSLNREYKNQLYKMVNELRYKYSL
                     SSSYSKIMKEKLKNSGDVQISFFD"
     gene            32904..33734
                     /locus_tag="ACGI5H_000566"
     CDS             32904..33734
                     /locus_tag="ACGI5H_000566"
                     /EC_number="2.1.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423706.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008168 - methyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:1904047 - S-adenosyl-L-methionine binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HFG9696296.1"
                     /translation="MLNKLCMYLERPELYKQSEINFWDDEYISEQLLKAHLDTNFEGA
                     SRNFNFIEDSVNWIVTVANPVNYPKLLDLGCGPGLYAEKFAQKGYKVTGIDFSKRSIN
                     YAQNRNKETNLNINYLFQSYLNMNYNEEFDLATLIYCDYGALSTENRRLLMEKIYDSL
                     KPGGKLILDVFTINKYNNFEEIKYWEINEDGGFWSNEKYMCLQDNCKYNDYNTLEQTL
                     VITEKDENVFYVWNHYFSKESFLLEVENIGFKSVEFFSNVKGEAYSDDSMTMGLVLQK
                     "
     gene            34144..34278
                     /locus_tag="ACGI5H_000567"
     CDS             34144..34278
                     /locus_tag="ACGI5H_000567"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889716.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9696297.1"
                     /translation="MDLINTIDKVQQAHKPIDEIIETIRDIVDIIKILEPVYNFKSNQ
                     "
     gene            34783..35544
                     /locus_tag="ACGI5H_000568"
     CDS             34783..35544
                     /locus_tag="ACGI5H_000568"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896901.1"
                     /note="N-terminal region resembles flavodoxins. C-terminal
                     ferrodoxin region binds two 4Fe-4S clusters; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EFR1 family ferrodoxin"
                     /protein_id="HFG9696298.1"
                     /translation="MIGIYFSGTGNSRYCVEKFLQEYDITANSYSIEDNELLQHINNH
                     ENIIFSYPVQYSNVPKILKDFIINHSTLWNGKRVFIIATMALFSGDGSGVLARILKKY
                     GAITVGGLHVKMPDSIGDEKVLKHSLEYNRKLVIKAEKKVTKAAKKLKHGSPPKEGLG
                     FLSHIVGLFGQRLYFINKTNMYTDKLKINTEECIVCGKCVNLCPMKNLVIKNCMIVAN
                     GQCTMCYRCVNNCAKKAITLLGKKVVEQSNIKKYM"
     gene            35609..36391
                     /locus_tag="ACGI5H_000569"
     CDS             35609..36391
                     /locus_tag="ACGI5H_000569"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430254.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0016853 - isomerase activity [Evidence
                     IEA];
                     GO_process: GO:0009058 - biosynthetic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PhzF family phenazine biosynthesis protein"
                     /protein_id="HFG9696299.1"
                     /translation="MEYYIVDSFATKLFKGNPAGVCVLDRRIPLELMQKIAEENNLPE
                     TAFVVKCKGNYELRWFTPKAEIDLCGHATLAAAYVISNFIDVNVKRIDFFTQSGKLEV
                     TRNGNLYEMIFPEIMPIEIELSPQQANLIGCVPSAVYSSRDLILLLNSEQEVINYKPN
                     YAQLRKLTDWLGIIITAQGSNTDFVSRYFCPELDSEDPVTGSSHCNLIPYWSEKLGKH
                     KMVAAQLSNRGGIIQCEVLKDNTVKISGEAVLFMQGTIKIDI"
     gene            36658..37077
                     /locus_tag="ACGI5H_000570"
     CDS             36658..37077
                     /locus_tag="ACGI5H_000570"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861328.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YjdF family protein"
                     /protein_id="HFG9696300.1"
                     /translation="MDKISGKLTVLFEEPFWVGIFERQDGKKYEACRVVFGAEPKEVE
                     VYEFILERFFSLDFGSIKLEKNVTKDNIGYKRMQRKVKKEQEKETIGTKAQNALKLQY
                     EERKQDRKNLAKNRKEEEKERLFNLKQEKRKAKHKGH"
     gene            complement(37180..37446)
                     /locus_tag="ACGI5H_000571"
     CDS             complement(37180..37446)
                     /locus_tag="ACGI5H_000571"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896904.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1294 domain-containing protein"
                     /protein_id="HFG9696301.1"
                     /translation="MKNFILIYFIVINSIAFFSMYIDKKRAIRNEWRIKEATLMSIAV
                     IGGSIGSIIGMYSFRHKTKHIKFTFGIPFILFLQFLLVYFYILK"
     gene            37673..38374
                     /locus_tag="ACGI5H_000572"
     CDS             37673..38374
                     /locus_tag="ACGI5H_000572"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454365.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0004826 - phenylalanine-tRNA ligase
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phenylalanine--tRNA ligase beta subunit-related
                     protein"
                     /protein_id="HFG9696302.1"
                     /translation="MKFIVEKEVFDKLENVCFGVVVAKGIDNTKEIERISNLLDISID
                     RVEDYFKDKKVKESEEIIPYREAFRSLGMNPNKFMSSIEAMTTRVAKNKKLPHINPIV
                     DLGNSISLKYLLPMGAHDMDFRNDDVYVRFSKKGDKFVPFGETDVELMEEGELIYSVG
                     DMVKTRRWIWRQGEEGKITNSSKNIFFPIDGFTDANLDKVMSAREELAKLLKEIFNCE
                     IKVGFVDKDNPEMEI"
     gene            38456..39064
                     /locus_tag="ACGI5H_000573"
     CDS             38456..39064
                     /locus_tag="ACGI5H_000573"
                     /EC_number="3.6.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423726.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
                     /protein_id="HFG9696303.1"
                     /translation="MKKTIIKNVNPMIENKFIGLFEIEYKNKLDEDKVWMVASRKSSE
                     QLKNIYLKNEEDSVDAVVIVGLHKSSKKLILIRQFRVPINGYIYELPAGLVDEGESID
                     ISVERELREETGLTLLEIKKNKSIDKVYLSPGMSDESVAFVYCICDGDITDEFLEPDE
                     EIEALLISQEDAKEILQSNHKIDTKAFLILQMFVSLGAKLFE"
     gene            39388..39852
                     /locus_tag="ACGI5H_000574"
     CDS             39388..39852
                     /locus_tag="ACGI5H_000574"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439554.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4624 family lipoprotein"
                     /protein_id="HFG9696304.1"
                     /translation="MKKLVIILISIISMVSLTACKKSNESKYNNLNNKESGQTTIEMD
                     LDKNYDTSDPFVNARLFCVSNDIDVLDTEISFKMDGDSGIVEIKDNKTYETLWSNTWH
                     GSVDNDTFTISLSNIQKEKEYAICFTGIKINHAVVKVTFESNLVKEKEKPSK"
     gene            40489..41505
                     /gene="gap"
                     /locus_tag="ACGI5H_000575"
     CDS             40489..41505
                     /gene="gap"
                     /locus_tag="ACGI5H_000575"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889722.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016620 - oxidoreductase activity, acting
                     on the aldehyde or oxo group of donors, NAD or NADP as
                     acceptor [Evidence IEA];
                     GO_function: GO:0050661 - NADP binding [Evidence IEA];
                     GO_function: GO:0051287 - NAD binding [Evidence IEA];
                     GO_process: GO:0006006 - glucose metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type I glyceraldehyde-3-phosphate dehydrogenase"
                     /protein_id="HFG9696305.1"
                     /translation="MKIKVGMNGFGRIGRAVLRIAQEELGDNIEIVAINARATTESLA
                     HLFTYDSCYGTFRGEVEAKDEDTLVVNSKEIKILRYNDPEELPWKELGVDIVIESTGL
                     FTQREKAEKHIKAGAKKVIITAPGKNEDITIVIGVNEKEYDNEKHNIISNASCTTNCL
                     APFAKVLDEKFGIVKGLMTTVHSYTNDQRILDKSHKDLRRARAAAESIIPTTTGAAKA
                     VSRVLPQLEGKLNGFSLRVPTPTVSLVDLVCELKENVTSEQVNSVLKDAAEGELKGVL
                     GYCDKPLVSIDYKGDSRSSIIDALSTMVIEDNMVKVVSWYDNEWGYSSRTVDLVKYVA
                     EKLK"
     gene            41900..43069
                     /locus_tag="ACGI5H_000576"
     CDS             41900..43069
                     /locus_tag="ACGI5H_000576"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902759.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9696306.1"
                     /translation="MEKLTDRRQVKAVSMETFIFLILLVVGFGYVGSIMGAGMMFKVI
                     MSTAHALLLETVFLIMAMAVLAGALSALLSEFGVIALINKIFAVFMKPLYGLPGASIA
                     GAITTYLSDNPAIIPFAKDKTFTQYFKQYQVPALCNLGTAFGMGLILTTFMISQGTEY
                     VLPALIGNLGAIIGSVISVRIMLTFTKKFYKYSPEEDKATGTLEKKDEFREIREGNVF
                     QRALDAILEGGKMGVDMGMAIIPGVLVVCTLVMLLTFGPSTDPVTGQEVYTGAAYEGI
                     KLLPVIGDKLGFILEPLFGFTSPEAIAFPITSLGAVGAAMSLVPEFIKSGAITPNDIA
                     VFTAMGMCWSGYLSTHIGMMDALNARQLAGKAILSHTIGGLCAGAAAHFIFTLVG"
     gene            43449..47702
                     /locus_tag="ACGI5H_000577"
     CDS             43449..47702
                     /locus_tag="ACGI5H_000577"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861332.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl-CoA dehydratase activase-related protein"
                     /protein_id="HFG9696307.1"
                     /translation="MDELFHIGIDVGSTTVKVVVLNNSNNIVHKEYRRHYSDVKKSVK
                     EVLNGIYEKLGDINTTIIITGSGGIGISKKLGVKFVQEVISSTKSIEYFHPETDVVIE
                     LGGEDAKITYLSGGIDQRMNGICAGGTGAFIDQMASLLKTDASGLNELAKGYNVIYPI
                     ASRCGVFAKTDIQPLINDGANQTDIAMSIFNAVVVQTVSVLSCGRKIEGNVAFLGGPL
                     YFLSELREAFKRVLDLKDENIIFPENAQLYIAIGAGLLSVDEDNIQLKSLIEKLDSIK
                     NIEDGEVNLLEPLFKDKNEYEEFSRRHEKEKINYVDINSIKSNCYLGIDAGSTTTKAA
                     LIDEDGRLVYSYYNSNEGNPLKTTIKVINEVYDILPKNIKILSSTVTGYGEGLIKKAL
                     KIDNGEIETIAHYKAAKFFNKDVDFILDIGGQDMKCLKIKDGVIDNIILNEACSSGCG
                     SFLETFASSLSMTIEEFAHEGIYSQNPVDLGSRCTVFMNSRVKQAQKEGASVGDISAG
                     LSYSVIKNALFKVIKIRDLNEIGNNIVVQGGTFYNDLVLRSFEKLIGKNVIRPNISGI
                     MGAFGSALIAKEKYESGYKTSLLSKEELNNIKLEASVTRCKGCSNHCLLTINKFSDNE
                     IFISGNRCEKGEAIYGDKKIGLEKKKPINLFKYKYNRIFRYKPLEKEEAKNGEIGIPR
                     VLNMYEDYPFWFTFFNAMGFRVVLSDRSSKQLYETGITSIASETVCYPGKLVHGHIEN
                     LIAKGIKNIFYPSVTNENKEDSNADNYYNCPVVISYSEVIKNNVENIRNKNINYINPF
                     ISLNDKEKLKKRLYDELSRHFSDIKITKEEVNHAVDKATDEQNLFKMEIQAAGERALK
                     EIKERNMKGIVLCGRPYHIDPEINHGMPELINSLDMAVLTEDSICHLANVQRPLRVVD
                     QWVYHSRLYKAASFVRDKNYLELVQLNSFGCGLDAVTTDQVQEILNEKSKIYTIIKID
                     EGNNLGAAKIRMRSLKAAMFERESKNIDVKNIKVNRIQYAKNNQITNKHTILAPQMSP
                     IHFQFLEKAVNLSGYNIEILKDTDSSVIEEGLRYVNNDACYPAIIVVGQLITALKSGK
                     YDLNNTSVTITQTGGGCRATNYIGFLRKAIYDAGFKDVPVIALSVNGIEDSGIMDNIS
                     LKLINRLFMSVVYGDLLMKVLYRVRPYEKVTGSANALYEKWVDICKSSLVKAKISVFT
                     RNIKDIVKEFDNLEILDIKKPKVGLVGEILVKFHPIANNNLVDILEREGAEAVVPDLT
                     NFFLSCAFNTIYKHTHLEGSRKSRMIGEAFIYITGIYQRVYKKALDKSERFYAPANIK
                     NVAKSTEPVVSLGNQTGEGWLLTGEMVELLNEGVENIICMQPFGCLPNHIIGKGSIKE
                     LKRLYKNANIIPIDYDPSASEVNQLNRIKLMLSKAFKNI"
     gene            47851..48345
                     /locus_tag="ACGI5H_000578"
     CDS             47851..48345
                     /locus_tag="ACGI5H_000578"
                     /EC_number="2.1.1.63"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430263.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003908 -
                     methylated-DNA-[protein]-cysteine S-methyltransferase
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="methylated-DNA--[protein]-cysteine
                     S-methyltransferase"
                     /protein_id="HFG9696308.1"
                     /translation="MSLVYDVYKSKLGNLYILSEDGFIVSIYIGDEKFNNLKNECIKK
                     GIDIKRSKEDLKEAISQIDDYFNGKRKVFNLNIRIEGTEFQKSVYREMLKIPYGETLC
                     YSDIARNINNPKSVRAIGQASKSNKIPIIIPCHRVVGKKDIGGYMGNHSDLKEILLNL
                     ERQS"
     gene            48461..48838
                     /locus_tag="ACGI5H_000579"
     CDS             48461..48838
                     /locus_tag="ACGI5H_000579"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430265.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="C-GCAxxG-C-C family (seleno)protein"
                     /protein_id="HFG9696309.1"
                     /translation="MCDKVIASKYHEKGFNCAESVIKAYNEEFNTDIPVCLGSGLGSG
                     CGVASLCGAVNASNIIIGYVKGRNHEDESTKAKVYAKDLTTTVRKEYGSELCIDLKKD
                     LVACREIMDFAYDSLKETLKKEL"
     gene            49044..49484
                     /locus_tag="ACGI5H_000580"
     CDS             49044..49484
                     /locus_tag="ACGI5H_000580"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893285.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SufBD protein"
                     /protein_id="HFG9696310.1"
                     /translation="MKNLNLLINKLYSKNHNEAYKTFLFLENESLKSNITYCFFDSFL
                     EMIDNENSYIRTRGLLLISANAQWDIDNKIEINIDSILSHIVDKKPSVSRMFIKSIPN
                     ITKYKENLINRIKMELSNADISIYNNNMKPLVEKDINDTLSNIS"
     gene            50129..51436
                     /locus_tag="ACGI5H_000581"
     CDS             50129..51436
                     /locus_tag="ACGI5H_000581"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728608.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9696311.1"
                     /translation="MKEIADAITSEYLSYGINEDISIYEGRFCIYLDKKYRCNGKIYY
                     KMTPPISISFKADIGCVEEIDNEDDNLALDYDNAILEVHGYKIISITINTLSEFSVEG
                     YINDDCIKSKNSYVEYVDFNIINLDKIPGKLIKYNDKVYAGRIEFDINDYVVTIDKRY
                     DYRKELKSELKSKSGAIITHIGRIRRKDGRIFRTNNTINLLDRISTALSFMCGRYVGF
                     CLAKGYRSGNEVYRIWNENQISPFRYVPTWSDTLSNYHNMEKYISLMCKKLEDFYYGS
                     AIKSVVDWYIESLGSATMENNIISVQIALETLSYVILVEQNKILTDEAFDCNLASKNI
                     RLLLDTCKIPYGKHELNIFDNIIKNKFDDGVDLVIYLRNSIVHPSRKTHRAVLEVEDI
                     WNIISIGTRYIELVLLFILGYRGEYSNRLVERCYGEVEVVPWN"
     misc_binding    51522..51784
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            51910..52713
                     /locus_tag="ACGI5H_000582"
     CDS             51910..52713
                     /locus_tag="ACGI5H_000582"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423750.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter substrate-binding
                     protein"
                     /protein_id="HFG9696312.1"
                     /translation="MKNILKKVGIFTIMLGLLGGVVGCSKPDNEKDKDASKESKKEVV
                     VGFDNTFVPMGFLDEKGDTVGFDVDLAKETFKRLGMEVKFQPIDWSMKETELNDSKTV
                     DVLWNGYSITDERKKIVSYTEPYLQNKQIIVTLSDSKINSKADLKDKEVGTQQGSTAL
                     DAVEKDKDFMNSLKGGAPVLYDTYDKALRDLEIGRTSAVVGDEVLIRYYMGQKGEDKY
                     KVLKDDFGLEDYVVATSKENPELCEKINETLKEMKKDGTFDKIYDKWFK"
     gene            52751..53362
                     /locus_tag="ACGI5H_000583"
     CDS             52751..53362
                     /locus_tag="ACGI5H_000583"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430270.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA];
                     GO_process: GO:0006865 - amino acid transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HFG9696313.1"
                     /translation="MLQGLEIVIAMFCITLIVSIPLGIGVAFLRLSKNKLVSGITQCY
                     ILIMRGTPLLLQMIVIFYGLPLLGIVFDRFTAGVVAFFLNYAAYFAEIFRGGIQSIDR
                     GQYEASKVLGFDKFTMYKRVIFPQVFKRILAPISNEVITLVKDTSLVYILGLNDILRI
                     SQIAMNREASLLPLFEAGAIYLIFVAILTKGFELLEKKYSYYR"
     gene            53394..54065
                     /locus_tag="ACGI5H_000584"
     CDS             53394..54065
                     /locus_tag="ACGI5H_000584"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430271.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HFG9696314.1"
                     /translation="MLKIKNLNKSFKKNRVLKDISFELEEGQIGVLLGKSGAGKTTIL
                     RCINGLEEFDSGEIIIDNEVIKNKRDMAKIRGKIGMVFQNFNLFPHMTVLENIIESPV
                     NVFKVPRKEAEERARELLRLVDLEDKLNSYPFELSGGQQQRVAIARSCALMPKVLCFD
                     EPTSALDIDTIQRVVNIMNRLKDKGMTILIITHDVVFSNNVADKIISIKDGIVENVQI
                     KEKIV"
     gene            54364..54726
                     /locus_tag="ACGI5H_000585"
     CDS             54364..54726
                     /locus_tag="ACGI5H_000585"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433620.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arsenate reductase family protein"
                     /protein_id="HFG9696315.1"
                     /translation="MIKLYGYTKCSTVKKAKNWLKENNLEFEDIDMVQNPPSKEELKS
                     IYKTSGYDIKKFFNTSGMKYRELGLKDIVKTESDDKLLEILVSDGMLIKRPLLLDGKN
                     VLLGFKEDVWKSTLLKED"
     gene            55162..55863
                     /locus_tag="ACGI5H_000586"
     CDS             55162..55863
                     /locus_tag="ACGI5H_000586"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4253 domain-containing protein"
                     /protein_id="HFG9696316.1"
                     /translation="MSIEDLYDFECVPLNNEIDIDVLFEKMIEDGKEKEYTPIIVIDE
                     KVGLLRKNIDMITKEYGSLENYREYCLTKYNEIDVNQFFDFRKSEISELLKELIDLED
                     DFYDYKHFRPIMNIDIFHEYNKVYIAKIPTIKPYEVFAYIPIGGFNDCPRDEEHIAIA
                     KYWYEKHGIFPIAIGCDTVQYSVKNLTKDGKKFDELCIELVFYCEDIIIQGYETLKAL
                     KDVLKRSTIVLFWWD"
     gene            56134..56952
                     /gene="larE"
                     /locus_tag="ACGI5H_000587"
     CDS             56134..56952
                     /gene="larE"
                     /locus_tag="ACGI5H_000587"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016783 - sulfurtransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent sacrificial sulfur transferase
                     LarE"
                     /protein_id="HFG9696317.1"
                     /translation="MEVNFVKEKEKLDKLKKMLLELGSVVVAYSGGVDSNFLLKVAKD
                     TLGENVIAVTIHAMMHSSREIEEAKQYTQNFGVKHIILNIENFDLKEFKENGVDRCYH
                     CKKYIFSKIKEVAKEHNIKYIVDGTNIDDLGDYRPGLKALSELGVISPLKDSSLKKEE
                     IRSLSKTLGLNTFNKPSFACLASRIPYGVEITDENLRIVEKSEEYLSNLGFSQFRVRM
                     HGDIARIEVGQEELGKFFENNNFNKVDTKLKIFGFKYVTLDMSGYKMGSMNLNV"
     gene            57007..58155
                     /locus_tag="ACGI5H_000588"
     CDS             57007..58155
                     /locus_tag="ACGI5H_000588"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent RNA methyltransferase"
                     /protein_id="HFG9696318.1"
                     /translation="MKNYTLISPCFFGMEKMLAREITNLGYEIIKTEDGRITYKTDEF
                     GIAKSNMWLRCAERVHLKIAEFEAKSFDELFENTKRINWSRYIPYGAQFPISKASSIK
                     SKLYSTPDVQAIVKKAIVESLKKSYLEDGLLKEDKEKYPIFVFIHKDKVTISIDTTGD
                     ALHKRGYREKANKAPIRETLAAGLIYLTPWKAGRVLVDPMCGSGTILIEAAMIGINMA
                     PGLNREFISEKWRTLDKKIWWDVRKDAFNKIDNESKFKIYGYDIDEESIDIARENAEI
                     AGVDEYIEFNVGDATQFKSEDEFGFIITNPPYGERLEDKDSVKQLYKELGYAFRKLKN
                     WSYYLITSYEDFEYEFGQKADKKRKLYNGMLKTNFFQYPGPKPPRNNK"
     gene            58291..59679
                     /locus_tag="ACGI5H_000589"
     CDS             58291..59679
                     /locus_tag="ACGI5H_000589"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423771.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipoprotein"
                     /protein_id="HFG9696319.1"
                     /translation="MKVLKLITVVALMMLFVTGCNIKTESPEQLAKIPDYDDTKKVLY
                     DGIDQLLKPDSSMILPSNTKEVGKINKVDLNSDGIDELVVFEQKEDLSNNVSQVGFVT
                     LSYNGEKYVLGDHFLENGESIEYANFYDLDSDGYKEVILLVKSKDKTNMHIYKVVDNE
                     ITKIYDLDASWLQNKEDFNDMKVKIGYIDGDDKLDILMLHLNNKTNEMFASVANFDGK
                     MKIKDSVKFENVKNLSELYITLGNVASSVGNSSAAIKGIVLDIPILKDNNYITQILYM
                     KDGKINKAFSDYDKTITKSYYIPVDDIDKDKIIEIPIVAGSTGNNKNTYSSKSSATIS
                     WYRWNGKEGADSSLIFTSQIYYNYKYNFKLFIPNNLFDKILVEQEFVGEKAVFKFYYF
                     DYSDRKNLFNIVVESKNKLEDRKNTGTQNSIVLQESDEYTFLLVVNNANEMDKLDMTI
                     DALKEYFSLIYG"
     gene            59708..60406
                     /gene="walR"
                     /locus_tag="ACGI5H_000590"
     CDS             59708..60406
                     /gene="walR"
                     /locus_tag="ACGI5H_000590"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889742.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall metabolism DNA-binding response
                     regulator WalR"
                     /protein_id="HFG9696320.1"
                     /translation="MKEKILILEDEIGIRSFVSINLKREGYEIVEAGTGREAIEKMTT
                     EKDITIALLDVMLPDISGIEVCKFIRENFDQVGIIMLTAKAQEDDKIEGFISGADDYI
                     IKPFSIKELLVRVSALLRRVAKDDSSVKSSEIVSPPFILDIDKRKLFKNGKEIELTPT
                     EFSIVKYLISNAKQSLSRDQILDEVWGTNYLYDFKIVDVNIRRIRNKIEDDPSKPKYI
                     QTIWGYGYCFRKEE"
     gene            60409..61842
                     /gene="walK"
                     /locus_tag="ACGI5H_000591"
     CDS             60409..61842
                     /gene="walK"
                     /locus_tag="ACGI5H_000591"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430278.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall metabolism sensor histidine kinase
                     WalK"
                     /protein_id="HFG9696321.1"
                     /translation="MLHFEGLRKKVIKNYFIIIIIMVTLFEGLFMFYIQNYYYDSVKQ
                     LLESEIKYADEYNAITMETTSFEKKVKNIFDKQPLTKNSEFGISIIDKDKNIILDQYG
                     FKSKEKANYEDVNNALKDIKTKNLTPYTYRIPDTGEHVMSISLPLKVNNIIEGVVRYT
                     VSLDAIDNAILKQATWLILAGIFILIIAILISLKFAETLIKPLRELKKFANELAVGNY
                     NIKLEKMKIVDDEIGDLAQTFEHMAHEIDKSEKLKEEFISSVSHELRTPLTSIKGWSE
                     TLGYESITREELDLGLGIIQDETERLIKLVEELLDFSRLSSDRIKLHVDIVDVEGLIV
                     GVVNQLKVKAAEKDISLLFEFENEFIENIQGDKNRLRQVLINLIQNSFKFTSQGGYIK
                     VVASQDEEITTISVEDNGSGIEKQNLNKVLDKFFQEDYNKAGSGLGLAISNEIVKLHG
                     GRMKIESEKNVGTKITFNIKNKFAKQA"
     gene            61864..62601
                     /gene="truA"
                     /locus_tag="ACGI5H_000592"
     CDS             61864..62601
                     /gene="truA"
                     /locus_tag="ACGI5H_000592"
                     /EC_number="5.4.99.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018112838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0009982 - pseudouridine synthase activity
                     [Evidence IEA];
                     GO_process: GO:0001522 - pseudouridine synthesis [Evidence
                     IEA];
                     GO_process: GO:0009451 - RNA modification [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA pseudouridine(38-40) synthase TruA"
                     /protein_id="HFG9696322.1"
                     /translation="MRNIKMIVAYDGSRYKGYQKLGDNNMTIQEKLENVLSKMTNETV
                     EIIGSGRTDMGAHARGQVVNFRTNCMDSLDKIQKYLYEYLPEDIVVKTVEEVDERFHS
                     RYNVKSKTYMYKIDNNKYHSPFIRKYATHVSKKLDLDRMRKASEYLVGEHDFTSFASS
                     KSKKKSNVREIYSINIKEDDNVIEIYVEGNGFLYNMVRIIVGALIDVGLKRRAPQDIK
                     YMLESKDRCQSSDTAPAKGLCLWKVTY"
     misc_binding    62712..62919
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            63172..64371
                     /locus_tag="ACGI5H_000593"
     CDS             63172..64371
                     /locus_tag="ACGI5H_000593"
                     /EC_number="6.3.4.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896935.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004055 - argininosuccinate synthase
                     activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006526 - arginine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="argininosuccinate synthase"
                     /protein_id="HFG9696323.1"
                     /translation="MKEKVVLAYSGGLDTSIIIPWLKENYEDIDVIAVCGNVGQEDKM
                     EDVYEKALQSGASKAYVDDISEEFVTETIFKAVKAEAKYEGKYLLGTSLARPIIAKKL
                     VEVAHKEGAKYICHGCTGKGNDQVRFEATIAALDPTIKVIAPWRIWDIKSREDAIDYA
                     EKHNIKVTATKAKIYSVDANLWHVSTEGGDIEHLENEHKKDVYKQCVDPEDACDVAEY
                     VEVYFEKGVPKKVNGEELSPVALIHKLNELGCKHGIGVIDIVENRLVGMKSRGIYETP
                     GGTILYEAHNILESATLDKDTLHFKQMVSYKYGELIYNGLWYCKLRESIDAFMEQTQD
                     NVTGTVKVKLYKGNIKPAGIFTENALYDEGISSFGNSELYDHKDAEGFINLFTLPLKI
                     RAMKAGK"
     gene            64618..65664
                     /locus_tag="ACGI5H_000594"
     CDS             64618..65664
                     /locus_tag="ACGI5H_000594"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889743.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BtrH N-terminal domain-containing protein"
                     /protein_id="HFG9696324.1"
                     /translation="MRKIIEIKHHSHDYECMWNGIEDLYINKTGECLPNDFFFLLSGF
                     GSFCYMKTNKADLKRMVALGDGRTKQMYKFLAPIVGFEYKHHEFKKYEQALKKAKSEI
                     DDGYPVILGALDMYYLPYYKKLYHKEHIPFHYILMVGYDDEGIYLYDCGRTELLHLSY
                     DKLRESMNCNSPGLSKENTICTIRMNTSKNKYNIAREAIAIKRDMFLNPPKGFLGYKG
                     FEKFIKELPQWNTELDKDDYDKILTNMVMFFGTVPTIPNAIKGIKEPDTVQFKGGFDK
                     MSRMLNSIGEEYKNDSFIQVADIFDKTAIIIEKISNIIIDYLTQTCDDTGQLPLLFSE
                     VLEHMKTGYLILDV"
     gene            65772..66935
                     /locus_tag="ACGI5H_000595"
     CDS             65772..66935
                     /locus_tag="ACGI5H_000595"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728612.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HFG9696325.1"
                     /translation="MRTVKQVSDLTGISVRALHYYDEIGLLKPNKITDAGYRLYDDES
                     IKTLQQILFFKEIDIPLREVKEIMSSQYFDKVEALKNQKKLLILKRKRLDELIELINQ
                     TLRGEGNIDFKEFDMSEYFDVLEEFKREHRNKVIKIYGSVEKYNEYIERVKSNEEKIA
                     KMAIKQYGTIEKFAKAIKTNFSSDILNLGEKFDRYKNDCLKEKHPKLKELYRKLVEDL
                     NRNPSSTDLQEIAKEITDISKKDYEIFSMDTGDDNWYYMVQNYLVNPMWIEEVDKKYG
                     SGAGKFIGQVLKTYLRDRKPKINTLYEKLVEDLSRDCSSREVQSIVEEIDNEMKRSNE
                     FYKIDNGERYFDYMSELYLQDSNYIKVTDKNYGDGASKFIGEAFKIYFDNNNC"
     gene            complement(67024..67404)
                     /locus_tag="ACGI5H_000596"
     CDS             complement(67024..67404)
                     /locus_tag="ACGI5H_000596"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439516.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4363 family protein"
                     /protein_id="HFG9696326.1"
                     /translation="MKSTTFVILWTILFVLFGFYVNNKLYDFTEGYKDNISVLEKSIE
                     NEDWEKAQKEADSISTSWNKEKNHWYKVLNHEYFDEIGLRFNILDKAIYTENKLKSLE
                     EVESIKTYLGNIIESVKFDVNYIF"
     gene            complement(67407..68066)
                     /locus_tag="ACGI5H_000597"
     CDS             complement(67407..68066)
                     /locus_tag="ACGI5H_000597"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430290.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DUF421 domain-containing protein"
                     /protein_id="HFG9696327.1"
                     /translation="MTVVLIRSIILYITVLIALRVMGKGEIAEMNCFDLVITLLIAEV
                     ASVPMENNNIPIINGVAAISGLVIMQTLISFLSLKSRKLSSFLSGKPSVLIDKGKIVY
                     KELKKERISIDELLEQLRIQGYFNLKDVQYAILETDGNLSVVPASSYNSTPPRAFNHL
                     PIPLILDGRIINKNLDIAQKDTNWLMGILKSNHIETFKDVLICVLDENDKIFIQNKKG
                     D"
     gene            complement(68172..69146)
                     /locus_tag="ACGI5H_000598"
     CDS             complement(68172..69146)
                     /locus_tag="ACGI5H_000598"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433616.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004527 - exonuclease activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="exonuclease domain-containing protein"
                     /protein_id="HFG9696328.1"
                     /translation="MKYKLFIDFEFNILDDNKNKPKEYNGAELISIGGVLVDNEFNTI
                     DNYYSLVKPKYNKILSNKCKNLTKLNQLDINNAPNLLYVMDDFYKWFCKFDDVTIYNW
                     GDFDITGLLTSFRVYKYTGKCLELFNMMIDIQPFISQHITYNNRILSKQISLLNMKKI
                     FSVEGDIKHNSLSDAVDLMNVCKCFFFNSPKNIDILEELYNKLPALKTPLYYIPYFED
                     ENFELKFDRTPEDIIIYLKQILTILNISKKEIYFKKRSVLVNNSKIINFKNLSSSFKL
                     IKLNEFEEYPDFILKLGDKKSFVESVIKINKSNRKSIKNLILKLSKKP"
     gene            complement(69186..69533)
                     /locus_tag="ACGI5H_000599"
     CDS             complement(69186..69533)
                     /locus_tag="ACGI5H_000599"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433614.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9696329.1"
                     /translation="MLNLKEIREEIIKKYIGDSLISELTEELKNILITDLQSNPFKSN
                     IELSIIPANIEIFKKIENILIDSKVNLKMGWERILINYILKDLFELNYEINKSCNEPL
                     MFRVIISIDSYDA"
     gene            complement(69751..70707)
                     /locus_tag="ACGI5H_000600"
     CDS             complement(69751..70707)
                     /locus_tag="ACGI5H_000600"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902770.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-threonine 3-dehydrogenase"
                     /protein_id="HFG9696330.1"
                     /translation="MKKILITGALGQIGSELTIKLRNEYGEQNVIASSRRVKEGNPVC
                     ESGIFEILDVTDKNRFFEIAKKYDVDTIIHLASLLSAVAESKPLEAWNLNMNGLINGL
                     EIAKELDCKFFTPSSIAAFGENSPKNMTPQDTLQRPNTMYGVTKVSGELLCDYYHSKF
                     GVDTRGVRFPGLISYVTPPGGGTTDYAVDIYYEALKNKRYKSYIAEGTKMDMMYMPDA
                     LQSIVDLIEAPADKLIHRNAFNITAMSFSPEEIADSIKKYIPDFVIEYDVDPVRQSIA
                     DSWPNSLDSSSAVKEWNFKFSYDLDKMTKDMLEKLSEKGIGK"
     gene            71152..71520
                     /locus_tag="ACGI5H_000601"
     CDS             71152..71520
                     /locus_tag="ACGI5H_000601"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423793.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="C-GCAxxG-C-C family (seleno)protein"
                     /protein_id="HFG9696331.1"
                     /translation="MTRPSIYHSQGYTCAEALIKSYNEEHNTDIPISIGSGMGVGMNV
                     GSVCGAVNAAVVIIGYLNGRNSNLDENIARKYSRELLNRVRNKYSSEICVSLKKNKVT
                     CEEIINFTYDALNDMLKNQK"
BASE COUNT        28626 a         7284 c        11910 g        23738 t
ORIGIN      
        1 atactatagt aattttgact attgaatcca attagtacag caacgtctaa aatagacaag
       61 tcttttttta atatatactt tttgcttttt tcaactctaa ctttacttaa aaaattagta
      121 aaagtatatc cacttttttt cttaaataaa gaaaaaaaca acttttatta agttgtaatt
      181 cattacatat attacttact gttatatctt ctgagtaatt tttgtgaata taatctatag
      241 ttttctttaa gttttcttta cataaaacta agagttggtc tatgtttcat tttatcaagg
      301 catatttatt aaaaaatcaa tctctatttg ttaaaataat ttatgaatga tgttagaaac
      361 tgtaatatat tggatataat ataataaaca gataaactct gtattaagag gatatatagt
      421 ttatcttaat tataggggaa gtgaggatat attatggaaa gattaatgga actcatagaa
      481 agaaaatttt taaaggatgt agaactttta gaattagaag acatagaaaa tgtaatagaa
      541 tgcaaaatga cacagccata taatgctcat tataatgaat atttagtaaa agtaaaaaat
      601 ggagatgaag tagaagaata ttttgtgtat ttaaaacata gataaacata aaagaggttt
      661 atatttattt gtatgattat aaaataaata caagcctctt tttttgataa atataaaatt
      721 ataaaatttt tatttattta attttttcaa caacattagt caatattgaa tctaaatcat
      781 cactaatttc tgtaactcca ttatgagtaa tatctataat ttctttagtc ataggaagtt
      841 ctcctaaaag ctctaagtct aaatcatcta aaaacttttc agtagattct ccttcaaata
      901 acttgatttt tttagaacaa tcaggacatt ggatataact catattttca ataactccaa
      961 ggacatttat gttcattttt ttagccatat taacagcttt tgatacaatc atagatacca
     1021 aatcttgagg tactgaaacc ataactattc cacttatagg aatagattgc ataactgtta
     1081 aggcaacatc tccagtacca ggaggcatat ctattaataa atagtctaat tcttcccaaa
     1141 gaacatcagt ataaaattgc tttacaaccc ctccaagtaa aggtcctctc caaacaacag
     1201 gttcattttc atcatctatc ataaggttta tagacattac ttttatgtta tttgagtttt
     1261 ctacagggta aatataagag ccatcagaat aagcttttac attttttaca cccataagtc
     1321 taggaatact tggtccagtt atatctgagt ctaatatacc aaccttatat cccattttgt
     1381 ttagcttatt agcaagtaaa gcagttacag ttgattttcc aactccaccc ttcccactca
     1441 taacaccaat tatttttcca aatttattgt tagggttatt ttcaatagaa caatttgatt
     1501 gactattaca atttcccttt gatggacatg aattacaatc tgccatatct attacctcca
     1561 aactttaata tttattagat tatttgtaac ctacatatac tattttagta caattgaacc
     1621 ataaagtcat tatttaaaag caacttagaa gattttctat tgatttattc atagactata
     1681 gcaaaaagaa tacaataaaa aaattataac attcttgaaa aagtgattat ttcaatttag
     1741 ttatagaact tagtcatata aatatataga aaatatttta atatgttata cataacgggt
     1801 tattttataa gtttaactat aaattaggtt tatattttat aaaaatttgc taaaaaaaac
     1861 aattaaaaat tgtaaagaaa aaagatataa ttagaactgt agtaataaat gttttattat
     1921 agataataga gttttaagta tcttaaataa tatttggagg aatatgaatg gaattaagac
     1981 caagaagtgc aaaattagaa gaatttgata aagtaataga attaataaac tatgtattta
     2041 gaatatcaag aaatcataaa ccaactatga tggaagaatt tcctctttta ctaagtaaaa
     2101 ataatataga aaatatgatt ataatatcag aagatgataa agtgatttct gatgtaaact
     2161 atctaattca ggatgtatct attcaaggaa acagattgaa ggttgcagct ataggtggag
     2221 tatgtactca tccagattat gaaaagagag gctattcatc taagatattg gataaagtag
     2281 aagaaaaaat gttttatgat ggtgtagata ttgtaattat atcaggaaca agaagtctat
     2341 acagtagaag aaattgtagt ttggtaaaga gtttttataa atatacaata aaacctgaag
     2401 atgtaaaaat agcatatgaa atagttgaat ttgatgaaac taattttgaa aaagataatg
     2461 atttagataa aatgattgaa ctatataatc aaaatagtac tagatttata agaacgagag
     2521 atgagtttca aaaactattg catgcagcaa ctattgcctg gggaccaatt ggttacaaga
     2581 aggtatttat aaaggaaaat aataatataa taggatattt gataataaga acaataaaaa
     2641 aagaagattc tactgtagga gaagttgctg aaatagggtt aaactctgta aatgttgaaa
     2701 atatattgaa atatgttgca aataaatttg gattagaata tttaaattat aaagtacatg
     2761 tgaaaaatct taaagaccag ttgaaatgta atgggacaaa atctttggat tatcaacaag
     2821 gaactatgaa aataataaat tttactaagt tgtgtgatag tttaagaagt tattttagtc
     2881 aatatgtaga ttttgaatta ctaaaataca tggaatttaa acaagttgaa aataaatata
     2941 ttattaaata caaagaagaa gaacttgtaa tagaaaattt ggataagctt aataaactgt
     3001 tttttgaaaa aaatgaggaa cagtacaatg aatttaaaca tctaaaaaat atatatgaat
     3061 ttgctacaaa ggcatttcct gtagattttc catggactgc aaatttaaat tatcaatagt
     3121 tttagatgat attaaataaa attgattgat acctagagtt agtccttgtt aaataagaga
     3181 aattattgga tattgaaaaa gcaattttgt aagtaattag aaaggatgag tattatatgg
     3241 acatacttga tgatatagca gaatgtatat taaatatggg tgtagataat atagagaatt
     3301 tagtaaaaat tgctatagat aaaaatattg atgtggaaga tatttatgaa tatggtttaa
     3361 acaaaggtat gataggagct ttagataagt ttgagaataa ggaatactat ctttcagaag
     3421 ttatagtatg cacagatgca ttaaataaag gtattaatct tttgaaggga actggaaaag
     3481 taaagaaaaa atcaaaggga gtaattctga tgtctgtagt agaaggagat actcatgaga
     3541 taggaaaaaa tattgtaaaa gtaatggtag aagccactgg atataaggtt attgacttag
     3601 gtgtaaatag aaaaagtgaa gatataatag aagaagctat aaaaaacaat gtagatataa
     3661 taggcttatc ttcaatgatg acaactacaa tggaaaatat gaaatcggtt atagacgaac
     3721 ttaatatgat tgagatagat aaaagaccaa aagtaataat tggtggagga cctgtaagta
     3781 tggagtttgc agaagaaata ggagcagatg gatacagttc aaatgctcca aaagcagtta
     3841 aattaataaa taaacttata ggaggtgaag tttaaatgtt ttcagatatg actttacttc
     3901 agtatataaa tagtgaagat agaggttttt ttctgcctga tatgggtaca aatggattgt
     3961 tcttaataaa taaaaaggca tatgaagtat atgatagtgt agatttgcaa ttagaattag
     4021 caaagactat ggacaagtat tttgaatcag attttatata ctcattctgt gatgggatta
     4081 cattttgtga aactctgggt ttagagacat taagaccaga ttatgatttt ccaagtgtat
     4141 tgacacatac tataactgac agagataaat taagaaaatt agatgttcca gacccttata
     4201 cgagtggacg tatgccactc aatatagaga gcttatcagt tatatcaaaa agtattaaaa
     4261 aaccactata tgaatcgata caaggtccat ttacacttgc aggtcaatta gctggagcta
     4321 ctcaactttt aagatgtata ataactgata aaaaatttgt agaagaatta ttggaattta
     4381 caactgaatt ggtaagaaga tatgctgtag ctgcaaataa agcaggagca aaatatattt
     4441 caatagcaga gccaacatca gtaaccctaa gtaaagatag atttgatgaa tttatagtaa
     4501 aaaatttaaa taaaatctac aatgaacttg attgttggaa aggtatgcat atatgtggag
     4561 acaccagaga attattagat aatatgctaa gttgtaatat agatgcagta agtttagacc
     4621 aaattttaga ctatgaagaa attgctccaa tgattcctag agatatagtt ttgattggta
     4681 atttagaccc aataaaactt cttggacgtt ctaagccaga taagattaga agagagacgc
     4741 taaaattgtt aaagaagatg agaagatatg ataacttttt atgtgatttt ggctgtaact
     4801 gcttaaatac cactccagta gaaaatttac aagcagctat aaaggcagga agaattagtt
     4861 ataaagaatt agataggatt gatattgatg aattataata gtaataaaaa taaatatctt
     4921 ttaaaggata taaatttaga tgatattttt atagataaga atattgtgct aaagtttttg
     4981 gggtatggaa atagaaaagc tccagataca attagtaaaa tcgttgaaag agaaataaga
     5041 aatataaatg atattttaga tatcaagata tatataagtg aagttgatat taataaaaca
     5101 cctaaagaat gtaaaaaagc atttgctgta ctatatacaa taggggataa aattgatatt
     5161 aagatgaatg actatatgga aaattgcaat atgatggcag ggctagcatt ggataaaata
     5221 ggtatagtat gtttagatta tattaatgag aaaataaaaa tgtatttaaa aggaaagtat
     5281 gatagtctca aaatatcgca tgaaatatat ccaggagata aagattttga agtagagaga
     5341 caaaaggata tttataacta tgtaaaaaat aaatataata gtatagaaat agaaattaat
     5401 gattatcatc aactatcccc cataaaaagt gttgcaatgc ttattttaat gggggatgaa
     5461 gaaaatttag aatcaagatg tagtaagtgt cctagaaaat gcttttagtt aattttcaag
     5521 actaagattt gttttgtgta taaattgcaa taattttttt ggtcatttta tgtataaact
     5581 aaaaaaatta ttgcaaagta atattctatt taatttgaac agacttacaa actatagtag
     5641 tttctttaat tcaataagtg tatttatttc ataagttggt atatgattag tataatttat
     5701 actgttattg gaatttaacc aacaagtatc tattcctgaa tttattccac ctaagacatc
     5761 agaggttaag ctatccccaa ttattaaggc agaagattta tcatgacaat taaacttttt
     5821 gagagcgtat ttaaatattt caggatttgg ttttgatatt ttcaactctt cagatacaac
     5881 cattccatca atatatcctt ttatttttga attttcaagt cttttatttt gaactgcaga
     5941 aattccattt gttattataa caatagtata ctttttttta agatattgta atatatcgat
     6001 tgcacctgga attaaaaatg tacattcacc taaaaaattt aagtacattt tgctaagagt
     6061 ttcagaatca acatccaaag atattttatt tgcaaaaagt tcaaatctaa gtaatttaag
     6121 ttcattcaaa gttataatat ttttttcaag gtcgagccaa agcttatcac ttatatttct
     6181 atatgactct atataattct caaaattaaa ttctaaatca aactcagata gaagtttttt
     6241 aaaagcatgt gattcacttt tcttaaaatc aaataaagta tcatctgcat caaaaaatat
     6301 aaatttatat gtcttcatgg tttttactcc tttacaagat gactgcaaaa attactttac
     6361 tttcactatt tgagtcattt tgccatttat gttttgttcc taaaggaact tttacactat
     6421 ctcctttgga caaagtaaat tcatcatcat ccataaaaag tttaacttct ccctccaaaa
     6481 catatgcaat ttcatctcca ttatgagtaa tcctatcaac acaagaagaa gtgtttggag
     6541 ctaaatccat aattgcaaat tctaaattac cactagagtc tggaattaaa atctcatata
     6601 taacttcttt gcttccaggt aaaataactt tttttctatt atcatgtctt actatcaagt
     6661 tttttttatc tacttcagat acaaaaaatg taaataaagg aacatttaga gaagaggcta
     6721 tagattttaa tgaatttaca gatggattag caagacctcg ttctatttgg ctcaataatg
     6781 atggtgtaac atcagctagt tttgctaaat ctcgaatact taagttttgt ttttttcgaa
     6841 cttcagctat tttttcccct aaatttaaat cattcatata aatatcctct ctttttaatt
     6901 taaaaaatat taacttaaaa taatcaagta aaatgattat gtagtatgaa attattataa
     6961 catatagaat taggttttga aaaaactatg ttcaatataa ttaaataaat taaaatataa
     7021 ttgacaaagt ggatacagaa tacttaaaat atatttaaat aaaattaagc aaaagatagt
     7081 taatttatga taggagggga tattatgcaa ataacgactt ttggagctat atttggttta
     7141 ttaatagcaa ttattttaat tataaaaaaa tttcaagctg tatatagttt aatgttagga
     7201 gcatttattg gaggattagt tggaggagca aatataacac aaactgtaga ttttatggca
     7261 aatggagcta tgaatatatc accatcaatt cttagagctt tggcatcagg tgtattagct
     7321 ggaagtttaa taaaaacagg ggcagtagat aaaatatcag aacagattgt aaaaatattt
     7381 ggtgaaaaga gggctttatt ttcgattgcc atttcaacta tggtacttgc tggagtaggt
     7441 gtaaatttgg atgtatctat aataactgta gcacctatag gattatatat aggtagaaaa
     7501 ttaaattatt ctaaattgtc aatactatta gctatgttgg gagggggtaa agcaggtaat
     7561 ataatatcac caaatccaaa tactatagca gtagcagata atttttctgt caatctctct
     7621 agtgttatga tggcaaatat aattccagca attattggag ttgttattac agttatttta
     7681 gcaagtatat taataaataa aggaaataaa gtacaatcat atgaaatttt agagcaaaga
     7741 gaagatttac caagtttatt taaatcatta tgtggtccaa ttatagctat atttctattg
     7801 tttttaggaa atgtatctcc tatagttata gacccaatga tagcccttcc aataggagga
     7861 atcgtaactc taattgtcac aggaaacttg aacaattcaa gagaatattt aacttttgga
     7921 ttatctaaga tgcaaggggt atgcatatta ttacttggaa cagggactat cgcaggaatt
     7981 atacagatgt ctgaattaca acagagtaca ataggtgctt tacaattttt aaatatgcca
     8041 caatttttat tggcaccagt ttcgggtata cttatgtcat tagcaacagc atcatcaaca
     8101 gctggtgcta ctatagcatc atctactttt catgatgcta taataaatgg tgggctatca
     8161 ccgatttcag gtgcatcaat agtaaatgct gggtctagtg tattcgagca attaccacat
     8221 ggctcactat ttcatactag tgcaggtagt ataaacatgg atataggtga aagatttaag
     8281 ttaattccat atgaagcatt gataggaata gtaatgacta taatttcaac atctattcaa
     8341 ttagttttat aataaatata aatatttaat gaaaaaagta ggattttgtt attaaatatt
     8401 gaacttatta tagtaaaaaa gaagattgga gttttaaagt gaataaaaaa aagattgtta
     8461 ttatagggat tatttattca tttttagtag tattttcact tacaaatatg tatgtaaata
     8521 tggagtataa tctaaatgta tttgaatata ttaagaagtc acttccattt acagaagaag
     8581 aaaaaaagtg gttagaaaaa cacaagaatt tgatttacag ctctgaccaa agttcacctc
     8641 ctttgagata taaaggtaag gaagatggac agtataaggg aattattgtt gatttaataa
     8701 attctctgtc aattcaaatt ggtagagatt tttattttaa accaaataat tggtggaaag
     8761 aatctttcgt aaattcaata gatgatagta taaagttttt tgacttgatt ccatcaaaag
     8821 aaagggcaaa taaatttata tttactgacc caatatacac tttgagtgca aatatattga
     8881 aagataaaaa gtcccaagat ataaatagtt acatggattt aaaggggaaa acagtagcaa
     8941 ttccagaagg tgattattct ataaattttt taaagcaaaa aattcaagat ataaacattt
     9001 tattgactcc agatataaag actggagtca accatttaat gtctggaaaa gtagacgcag
     9061 ttgttggtga tgaaccagta ttgcgatact atataaataa ttatggactt tcaaataaat
     9121 acagtgtttt aagtaatcct atatatacta aaaaagcagt tcttgctgta cctaaacaat
     9181 atgaagagct ggttagtatt ttaaataaag gcatttttaa acttcagaaa aatggagtgt
     9241 ataaagattt aaagaaaaaa tggtattcta cgtataatga agttgatgat atattgtatg
     9301 agcgaggaat tgtgcctagt atttatcttt ttataggtat aattttaata tcaatttatg
     9361 ttttttatag ctatacatat ttgttaaaga tagaaatcaa aaggaaaaca gaacaggtaa
     9421 tagaaaataa aaaaacttta gaggcaactt ttaatagtat tacagatata ataatgcttg
     9481 tagatgaaaa taacaatata gtagaatcga acaaagtact atatgacttt atgggtgaaa
     9541 tgagttataa gatagcagat ttgattagca tgataaaagg tgttattgaa aataccttct
     9601 ctgaaaatac taataaaact agtgaaatag aaatacacaa taaaatttta aagataaaca
     9661 cttttcctgt agagtataaa aaaaataata ctgagtatat agtagttctt attaaagata
     9721 taactaatga taaaatagta gaggcgaaat tacttagaga aaacaaaatg atatctatag
     9781 ggcaattagc ttctggggta gcacatgaga taagaaatcc tttgggtata ataagaaata
     9841 attgctatct cttaaaagat aacgttacaa tggaagaagt aaatgattgt gttaaatcaa
     9901 tagaaagtaa tgtagatagg gcaagtaata taataaccaa cttgttaaat ttcgcaagaa
     9961 tatcagatga taatttagaa catataaata taaaaaattt tattgaaaat atagtgaaac
    10021 ttcaatataa aatgttacag ttaaagaatg ttgaaataaa aattgactgt gaacataatt
    10081 taatatgcta tataaatgga gaatcgttaa aacatgtatt tataaattta atttctaatt
    10141 caatagatgc aatacatcaa gatggaaaaa ttattatata ctgttatgaa aaaaatcatt
    10201 gtttatttat agattttaaa gataatggtg aaggaataaa agaagatgtc ctaaaggaca
    10261 tatttaatcc cttctataca acaaaaccaa ttggtgaggg aactggttta ggtttatata
    10321 ttacttataa tgagattaaa aagaataatg gagatataag tgttgaaagt aaattggggg
    10381 ttggaacttg ttttcatata aaaattccat taaataaaga ggtgactata taatgaaaat
    10441 actattagtt gatgatgagc tagaatatgg agtggtaatg aaaaaaattc tacaaaagaa
    10501 gggctatctt gtagatatag cactaagtgg tgaagaagct ataaatataa ttaaaaaaga
    10561 taaaaattat gatttggttt tatctgatgt tatgatgaaa aatatggatg gagtacagct
    10621 attagataga attaaatcta ttaatagaga tatagaggtt atattagtta caggatatgg
    10681 aagtattgaa aatgcagttg atgctatgaa aagaggagct ttatcttatt ttataaaaag
    10741 taatcccatt gaaaatttat tagaagaagt tgaaaaggta aaggcaagta aaatatctgt
    10801 ttctgtacaa aaaaataatt ttgaatttac tttggaatct aaaaatagag attttaataa
    10861 tatcataaaa atagcaaaaa aagctgcttg taaagatgtt aatatattaa tcttggggga
    10921 atctggtgta ggaaaagata tattagctag atatatacat agcataagtc caagaaagaa
    10981 tgagatattt gtacctgtaa attgttgttc tttttcagaa aatctattgg agtctgagct
    11041 gtttggtcat gaaaaaggtt cttttacagg agcagtagat agtagaaaag gtagatttga
    11101 actttcgaat aaaggaactc tatttttgga tgaaatagga gatatacctc taaatgttca
    11161 ggtaaaactt ttgaggacac ttgaggacaa atctatagag aggataggaa gtaataaatc
    11221 tattaaagtt gactttaggt taatttgtgc tatgaataaa gaaccaaaag tggaaatatc
    11281 aaatggaaat ataagagaag atttttttta tagaataagt acaataacaa taactatacc
    11341 accactaaga aagagaagag aagacttaac tactcttata gaatttttct taaataagta
    11401 ccaaattgaa catgataaaa agatacactc gattgataag gaagtaaagg attttttatt
    11461 aaattacaat tatccaggaa atataagaga attaaaaaat ataataaata gacttgtagt
    11521 tttaagtgaa gaaggtaatt tatcaaaaga caatttaaat ttaatatcaa ataatgtata
    11581 catagatgat aaaataagta ttagaccttt aagagaaata agaaaagagt ttgaatgtga
    11641 gtatattgaa aaagttttat ctttgtgtgg aaataatatt tcaaatacag ctaaaaaatt
    11701 ggagattagt agaagacagt taaccaataa aatatcagag tataatatta agtgagaaaa
    11761 aaacttctca ttaagtgaga aaaaaatttc tcaaactgta ttaaaagata aacagaaaaa
    11821 atctgtttat ctttttttat tataatttta aaaattaata tttacaataa ttattgctaa
    11881 attcaatatt ggtgtaaatt aaaaatgaaa atttctatga cattaataca tagaatatat
    11941 attttaaata attggcatag aaaatgcttt atatattaat aaacgtaata aatactttta
    12001 attgcgatta aatatattaa gggggatttt catatgaagc tagagctagg gaatatattt
    12061 ataaaaaatg ttgaatttgg agaaaagaca gaagtaaaag atggagtact atatattagt
    12121 agcgaagaaa tagaaaagat agtattagaa gatgaaagga ttgtaagtgt aaatgttgaa
    12181 cttgcaagac ctggcgaatc aataagaata gctccagtta aagatgtaat agagcctaga
    12241 gttaaaattg gagatgaaag caaaatattt cctggaatta taaataaagt gaagactgta
    12301 ggaagtggaa gaacccatgt acttttagga gcttgtgttg taacttgtgg aaatatagtt
    12361 ggatttcaag aaggcgtaat tgatatgagt ggtcctactg ctaaatatac acctttttca
    12421 aaaacaaata atatatgtat tgttataaaa gcaaaggatg gtatagatac tcatgattat
    12481 gaagaagcag ctagaattgc aggattaaaa ataggtgcat atgtaggtga ggcaggaaga
    12541 gaagttgagc cagatgaagt cattgtatat gagacaaagc cattattaaa acaagtaaaa
    12601 gaatatccag acctgccaac agtagcatat gttcacatgt tacaatcaca aggactttta
    12661 catgacactt attactatgg ggtggatgct aaacagatag tgcctacatt tatgtatcca
    12721 actgaaataa tggatggagc tataatatct ggaaactgtg tagcaccatg tgataaggtt
    12781 acaacattcc atcatttaaa taatccagtt atacatgact tatataaaag acatggaaaa
    12841 gatttaaact ttataggagt tattttgact aatgagaacg tattcttagt cgataaagag
    12901 agaagctctg atatggtagc taaattaata gaatttttag gagttgatgg agttctagtg
    12961 acagaagaag gttatgggaa tccagatact gacctaatga tgaattgtag aaaatgtagt
    13021 gaagttggag caaatgtagt tttgataacg gatgaatttc ctggaaaaga tggcaagagt
    13081 caatctatag cagacgctac taaggaagca gatgcagttg tttcttgtgg tcaaggaaat
    13141 ctagtggttc atttcccagc aatggaaaaa attataggaa ctttagatta tgttgaaatg
    13201 atgataggtg ggtataaagg atgcttaaat gaagacggaa gcatggatgc agagctacaa
    13261 attataatag catcaactat agcaaatggc tataatcatt tgacagcaag atattattaa
    13321 ataagtattt gaatataaag ttctgttgat gtaatcattg gtctaactga tgtaataact
    13381 ataaagtgat ttggaggatt aagagatgag taaaatcaga gtggttcatt atataaacaa
    13441 tttctttgct ggtataggtg gagaggaaaa agcagatatt ccgccagaaa aaagggctgg
    13501 tgtagtagga cctggaatag catttcagag tcaatttaat gatgatgcag agataatctc
    13561 aactgtaatt tgcggagata cgtattttgg tgaaaatatt gagagtgcaa ctcaagaact
    13621 tttaaaaatg ataaaagaag aaagccctga tttatttatt gcaggcccag catttaatgc
    13681 aggtagatat ggagtagctt gtgggactat ttgtaaggca gttgaagaag agttaaatat
    13741 tcctgtaatt acaggcatgt ataaagaaaa tccaggtgta gatatgttta aattagattt
    13801 gcatatagtg tctacaggaa attcagcagc aagtcttaga aaggtagttc caataatgac
    13861 gaaactaggt cttaaattgg ttagaggtga ggaaatagga cctcctgaag aggaaggata
    13921 tataatgaga ggaataagaa aaaatttctt ccatgaactt agagggtctg aaagagcaat
    13981 tgatatgttg gttaaaaaga tgaaagggga aagctttgaa actgagtatc caatgcctga
    14041 atttgataga gttacaccta tgaaacctgt taaagattta tctaagataa aacttgccct
    14101 agtaacttct ggagggatag ttccaattga taatccagac aaaattgaat cttcaagtgc
    14161 tactaaatat ggaatttacg atttaacaga tatggattct atgtcaaata aagaatttac
    14221 aactatacat ggggggtatg acagagcata tgtccttgaa aatccaaatt tagttgtacc
    14281 actagatgta gttagagagc ttgaaaaaga aggtgtaatt ggagaattag tagattattt
    14341 tataactact acaggaacag gaacgagtgt tggcaattct aagagatttg gagaagagtt
    14401 ttctaagaaa ttgttagaag atgatgtaga tgctgtaatt ttaacttcta catgaggtac
    14461 ttgtactcgt tgtggagcaa cgatggtaaa agagattgag agagctggta tagcagttgt
    14521 tcatatatgt acagtagtac caatatcact tacaatagga gctaatagaa ttgttccagc
    14581 agtagggata ccatatccac ttggaaatcc tatgttagga gaagaggaaa gtaaaaaaat
    14641 tagaaagaat atagttttaa aagctttaaa tgcactaaca gaagatatag aagaacaaac
    14701 agtatttgaa taataaaaat acaacacaac actgaaataa aaaaagatat caaaaaataa
    14761 ttttttaaaa ttattttacg atatcttttt ttattaggta aattcgaaat ttgcattttt
    14821 ttaaattaaa tttataaaag tgataaatta gtttattata atattgatac acaaattcaa
    14881 attagatata ctatgaaaag cgagattatt acattttgga acaaatattc aacatattag
    14941 atcatattaa ttgaacagaa aaaattaact ttatataata attagaataa tgataagaaa
    15001 gaaggtgtat atattgattt caattgccat ttgtgatgat gaatcctata tgctaaatca
    15061 tttaaaggaa aatatagaat tatacatgaa gcagaagaat ttattatata atatagagct
    15121 ttttaataaa gtagaagatt tactatgcaa tcatgaaaag tttaatattg tatttttaga
    15181 tatacagatg gaagagatta acggaatgca ggcagctaga aaattaaggt catatggtaa
    15241 tgagtgcttt ataattttcg ttacagtttt aaatgaattt gtatttgatg cttttgaagt
    15301 agatgctata aattatctga taaaacctct atctaatgag aaactatata aaactttgga
    15361 taaaatagtt acaaaacttg atgataatga aagtaattat atcacaatac aaaaaggtta
    15421 ttcatattgg aaattaaaac ttgctgatat tttatattgt gaagttataa aaagaaagat
    15481 ttatgttcat ttaaagaaag agactgtaga ttattatgag actattgaaa atttagagag
    15541 aagtttacca acaaattttt ttaggtgtca tcgtagttat ataatcaatt tacaatatgt
    15601 atatggatat gaaaatggta atgcagttat ggaaagtgga gatagaatac ctgtttctag
    15661 actacgtcaa caaatatttt caaaagttat gcttgagttc atgaaaaata ggaggatata
    15721 agatgattaa tttattttct tccgatttat ttttaaagta cagttttttc ttctctttta
    15781 ttgtatatag aattttaatg gtaatagtgc aatactattt tctaatcaat tttacaaatt
    15841 ttaattcaaa attttggtgt tttattttat attcgataat ttcaattttt ttaatcatta
    15901 taaatacata ttttaattta tataatttat tttcttcaca gattctattt tttcttatga
    15961 cttttttatt tgtaaagtac ataataaaac aatctactgt tttatctata gtatcaactt
    16021 tgttagtata tttaattgaa caattagtat atggatttac agctccatta aattacttga
    16081 tatttactag tgatataaat acagatattt ataaatttga tataaatatg ggactatctt
    16141 ctttaattac tattataata gctggattta tatattggta tagttctaaa aagtttaata
    16201 ttaaggtcat gaactttgat aaatatatag caattttgat gattccattg ttgcttataa
    16261 tattatttat gcaatcattt gaatatagtt caaatataaa tatagataca agtcttggga
    16321 ttgtaaagct gctattaaat acttctataa ctgaagaaat tcaagctttt cttttttcta
    16381 taattggaac tatatgtgta tttttttctc tatttacctt taagaaacta attcaagctc
    16441 tcgaagatga caaggagagg gcaattatga atcaacagat tcatgctcaa aaaaactata
    16501 ttgaagaagc gaaatcacga ttatcacaaa ctatatcctt tagacatgat tttaataatc
    16561 atttagctat tgtcaatgga ttgttgaaaa aagaccaaat tttaaaagca caagattatt
    16621 taaataagct tgaaaaagta acaagtgacc tatcattttc ttgtaataca cagaatattg
    16681 ttattgatgc tcttttcaac aataaattaa gtatagcaaa acaattaggc atagaggtag
    16741 attgtgaagt aattataccc caaagcacta acatgaacga ttttgaccta tgtatagtgt
    16801 ttgctaatgc tattgacaat gcaattaaag cttgtagagt tgtagataaa caaaataggt
    16861 atttaaagct ttccactaag ttagagggtg gattttttat gatagaaata aaaaatagct
    16921 ataatccaat aaataattat acaagtggct caggtatagg tcttttaaat ataaaagaaa
    16981 ttgctaaaaa atatcaaggg gctataagta tagataagac atcagactat tttcaaataa
    17041 atgtattgct agttatttca ttacattgcg ctagtatttg agaacaattt cattgaaaat
    17101 agtatttgta agctatatta tgtatttgaa aagagaaagt ttgatatata gaaatgagga
    17161 ggttactaaa atgaaagttg gaaatataaa tggtcaagca ccaattacaa atggtttaga
    17221 tagttgtcaa agtgaggtac aaggcttaga acaaaagaaa aaagcattac aggatgaaat
    17281 agagaaagta agaagtgata aaagtattga tggtgaaacg gccaaattaa aaatagaagc
    17341 tttaaaaaaa gaaatggaag agattgaaaa taaaattcaa gagttaaaag gaaataaagg
    17401 aaaaaaaaca aataaagaag aaaataacgt ttcagaagta aataataatc tattagagag
    17461 aaaaaaagaa ccttctaata atgaaaatgt aaaacaatta tatgatgttt ttgaaagaag
    17521 caatgtagac gaacaatggg ataatactta tcgtgttctc caagatgata aaaacttaaa
    17581 agtaaaattt aatagaccta tatagtttat ttataaaaat agttaatatt ttaattatca
    17641 ccacttttta gaagaataca cactttattt taaagaccca catatttatt tacagttagc
    17701 acatttatat gtggttttat aactattatt tacaagtcta tattgataac ttttacatag
    17761 tatatgatgt ttaaatactt attcaaattt atctatacat aaacaaaaaa agagatttta
    17821 aaatctcttt ttagattgtt gacttatggc tttttgattt aataaaatca agaagccgtt
    17881 tgaattttat atgttggctg atacccttct gatattgaaa caccattttt gtttccaaaa
    17941 tcgtttaaaa ttaagaactt attatgaatg actatttcat tatgaacaat aagcaaataa
    18001 catgaatctt caatcaatgt tttaacagta gcattaaatg cttgcttata tagttctatc
    18061 gtttgtttga actgcccatt aaagtaaata tgagtcaata acataactat atctacacaa
    18121 attaatataa attttttata ctgtacatta tctaactgtt gattatctgt attacaacat
    18181 gattgaattt aaaaagccat caacacatag aatgttgatg gcctgaaaat agattttaaa
    18241 atctcttttt tattatatat taattatttt ttaaatttat attttttgca tcagattttc
    18301 taatagctaa gtcaaaccct ctaaatctaa tcactatagg gtcattaaga ggagctatct
    18361 ttttcacttc aacttcagtg ccatctatta gtcctaaggc tagaagtctc ttcataagtt
    18421 tttcatttcc agctatattg tctataattc ccttttgtcc aagttttaag ttgtaaacag
    18481 tcattattaa cacctcctaa tgaaaatcat tatcaaactt tatatttata atatataaca
    18541 aaaagagcaa attgtcaata tataacaaaa aataaacata ctaagttagt atgtttataa
    18601 aaaatagtat acatgggata ctaatagcat ctagcaaaaa accacttact aatggtacaa
    18661 ctaaaaaggc ttttggagaa tcaccatatt tttgtgtcaa agaactcata tttgccagag
    18721 cgttcggagt agctcctatt ccatgtccaa tcaaaccact tattatgatg gcagaatcaa
    18781 aatcttttcc aagtactcta aagcaaataa atattgaaaa taggattata aagattactt
    18841 gaaaagttac tattaagaga ataggaggta ataatgtaga taattcaaat aaatctatat
    18901 tcataagtga taaagttaaa aaaattccca atgaaagttc ttttaaaaaa tctataagtt
    18961 taaaatttaa ttctagtata tttatcttat catttaaatt tctaaaaata acagccgaaa
    19021 acatacaagt tacaacagag ggtaatagta tattaaacgt tatatagaag catctactta
    19081 taatttctcc tgtatttata caaataaata tgagaagaac ctgttccaaa aatacagatg
    19141 gtgttattgt ttcggagaag ttattatttt ttatcctatt cttatttcta aaaaatttac
    19201 ttccaaatct ctttagattt ctattatatc taggaatcga caagtctata tttgatgatg
    19261 gttttaattt atatttattt attagaaatt tagctacagg acatcccaat ataccaccca
    19321 taataagtcc tattgttgca gcagataatc caaccccaac tgctccttct ataccaagat
    19381 tttctattgt aagtccaaat gcagcagaat aaccatgacc accttccata gatacatttc
    19441 cacacataag ccctaaaaga ggttcaagtt ttataatctt tgatattgta atagctaata
    19501 tattttgaca aaatgccaat actccacaca aaatccaata tctaaataat acactaccac
    19561 ctttctttat aagatttatg cttatttcaa gtcctatagt tgtaaaaaag aaggttatga
    19621 aatttggcat taaatttcca cttatagata tatctgctat attaaaatat ttaaaaaata
    19681 aatttagaaa acaaaataat agacctccta ttactggtgc aggtatacag aaattattta
    19741 aaaagttaac tttattcttc aataaattac caattaaaaa gaagaatata gatagtgtca
    19801 aggtttgcac tatatcaaaa cttaaggtaa tcaaaataag tcctcctttg taattcaaag
    19861 ttttaattat ataacttaaa ttcttatgta ttgaaatttt attatcaaat gtatattaat
    19921 aaatgtatat taaaaagaat cagtagatat aattagatag tcataaatta aattaaaata
    19981 ttttaatgag atatgacttt tttagaatta aaaaccgtag tatattgata taatagaaat
    20041 aagacttaaa aatctgttga tagtattatt tataagtaca gtaggaggat aaaatgtttg
    20101 aaaatttacc taagatagat ttacattgcc acttagatgg aagtgttaga gtagaaacca
    20161 tgcttgatat agctattaaa gagaaaatag atttaccttc aaataatatg gatgaaataa
    20221 aaaaattagc aaaggtttct tttaattgta cttcactaga tgaatattta gaaaaatttg
    20281 atttaccctt aaaagtaatg caatctaagg aaaatttaaa aagaattact tttgaacttt
    20341 tggaagatgc aagtagagaa aatgtaaaat atattgaaat tagatttgca ccattacttc
    20401 acacccaaaa aggtatgagt gttaaaaata taattgaggg tataattgaa ggaattagag
    20461 aagctgaaag tatttatgat ataaaaggca atttaatatt aggttgtatg agaacaatga
    20521 cctcaaaaga ggcattatta gtaattgaag aagggaaatc atttgtaaat aaaggtgttg
    20581 tagcagtaga cttgtgtggt ccagagaaag agggattttg taaggaatat aaagatgttt
    20641 ttaaattagc aagagaatat ggatataaag ttacaataca tgcaggagaa gctgcaagtg
    20701 gagaaaatgt attggatgct ataaatattt taaaggcgga taggattggt catggggtaa
    20761 aaattaaaga ccataaaaag gcgtataatt tagttaaaga taaaaaaata ttgcttgaat
    20821 tatgtccaac tagtaatgta caaactaaga cagtagattc ttatgaagca catccatttt
    20881 atacttttta taaagataat ttacatgtaa gtataaatac tgataataga actgtatcag
    20941 atataaattt aagttcagaa ctaaatgtta tatttgatac ttttaaacta ggattagaag
    21001 actataaaat aatttataga aatgcagtag aagctagttt tgcagataaa gaaactaaag
    21061 agtatttgaa tagtttaatt taatagataa aaatatttaa actttaaatt aagctattaa
    21121 attgataaaa atacattgta ttaggagaaa aaatgtgaaa gattatgaag atgttgttta
    21181 tattaaacta gtcaaaaaag aacttgaaga atggaagaaa aatatattaa agaaaccttc
    21241 tatatttgac aaagcatcaa agggtataca gaataaattt aatggagtat tgccagataa
    21301 atatcatgaa ataattactt cttctataaa agtaatgaca aaaaccgtac tgtttggata
    21361 taaatatgct acaaagccat cacttagaaa tatgtcatta gaagaaagag aaaaattagt
    21421 tttagaaaaa gctaaaactt acaagactac agcaatgatt gaaggggcag gaacaggggc
    21481 aggaggaatc ctcttaggtt tatctgattt tcctttgctt ttaggtatta aagtgaaatt
    21541 tttatatgat gtagcttcaa tatatggata tgatgttaaa gattatagag aaaggattta
    21601 tatattaaat atattacagt tggctttttc tagtcaacag catataaaca aaacttttaa
    21661 attgatgaat aactgggatg aatatgtaaa tagtctacca gaagacatca atgattttga
    21721 ttggagaaca tttcaacaag agtataggga ttatttagat ttagctaagt ttttacaact
    21781 aatgcctgga ataggagcat ttgtaggatt ttatgtgaat ggaaaattaa ttgataaatt
    21841 atgtgaaact gctgtgtctg cttatagatt gaggattcga gagcttaagt tataagagaa
    21901 attataacat aaaaaattag ttatacaata tatctatatg tatctaattt tgcattgata
    21961 aaaacaatta tggataaaag gtaaagcatg atagaatcta atgtagaggt ttgtatttta
    22021 atggaaaaat ttagttttta ttgcttaaga tacaaattga attacgaaga gaagtaattg
    22081 ggaggaatat tttcatgaca aatttgccaa aacaatttga tagcttcaat gaagctagac
    22141 aaaaaggatt tataaatgca aaggaactta aggaaagtgg gaaaaagatg gttggagttt
    22201 tctgtacatt tactccagtt gaaattccaa tggcagctgg agcaactgta gtaggtgtat
    22261 gcggcgttag tgaagagcca atacctgatg cagaaagggt gcttccaaga aatctttgtc
    22321 ctttaattaa atcaagctat ggacatgcaa taacagatac ctgtccttat ttctattttt
    22381 ctgatttgtt gataggagaa accacttgtg atggtaagaa aaaaatgtat gaagaacttg
    22441 caaaagttaa gccaacatat gtaatgcatt tgccaaatac ttcaaaagga gaatttgcct
    22501 ataaactttg gaaagatgaa atgataagat taaaagaaga ggttgagaaa tctttaggtg
    22561 taactataac tgaagaagat ataagaactg ctataaaaga taaaaatgaa gaaagagaac
    22621 ttttaaaaga gttttatgca cttggtaaat tacaaccatc tgcacttaca ggccttgagt
    22681 tacataatgt tttatatcaa gcaggtttta aatttgaccg tgcagaactt aaacattctt
    22741 taagaaaagt tatagatgat atgaaagaaa gatatgaaaa aggtgaatgt cctgttcaaa
    22801 aagataagcc aagaatattg ataacaggtt ctcctattgg tggaataagc gaaaaaatag
    22861 ttaaaacttt agaagatgca ggggcatcag tcgttgcata tgaactttgt ggagctatta
    22921 gatcaaacga tttattggtt gatgaagaaa tagaagatgt atatgatgct ttaacacaaa
    22981 aatatataaa tataggttgt tcttgtatga tgaataatga caatcgtatt gaattattag
    23041 atagaataat agatgaatat aatgtagatg ctgtaataga tgtagtttta caagcatgtc
    23101 atacatttaa tatagaaagt tatagaataa gagaatttgt tacaaaagaa aaaaataagc
    23161 catttatgtc tcttgaaact gattattcaa aatcagatac tgaacaatta agaactagat
    23221 ttgaagcgtt tgtagagatg ttgtaggaat aaataaaagt aggaggaact atgtttagta
    23281 taggagttga ctcagggtca gtggcaacaa agggtgtgct atttgatggt gaaaaaatta
    23341 ttaagaaaat aattatacca actggatgga gccctaaaag tacatctaaa caggtctatg
    23401 agttgctaag tagtgaaatt gacaaaaaag atataaaaaa ggtggtaggt acaggttatg
    23461 gaaggggagt aatggatttt gctgataaga aagtaacaga aataacttgt catactagag
    23521 gtatttactt tttaaacaag aacataagga ctattttaga tgtaggtggt caagatagta
    23581 aagttataaa tttagataga gatggaaatg tatttaactt tataatgaat gataagtgtg
    23641 ctgcaggaac tggtcgattt ttagagatta cttctaacct tttaggaagc gatattgaaa
    23701 gtatagatac attagctaaa ggatatgaac cagttaatat atctagtatg tgtacagttt
    23761 ttgctgagtc tgaaattgta agtcttctag ctcaaaacat ttctactgga gaggtagcag
    23821 cagggatact taaatctatt gcaaataaat ccacctcaat gttagcaaga ggtgaggtaa
    23881 tagatgaagt tgcatttact ggagggcttg caaaaagtaa agaactagta aaaatgatag
    23941 aagaaatact gggtaaaaaa atttttattg cagaagatac tcaaataata ggagctttag
    24001 gagctgctgt aataggattt agataaaaac atataaaagg aaaatgagaa gctgaattta
    24061 ttataaataa attcagtttt ttattttatt ttatttattt ataaaggaaa actttggtat
    24121 aattgattta aatgattgta tatttgtaaa tacttgatat ttagtcatat ataacattat
    24181 aattttaaaa attagctcaa aataaggggg agaaagcgtg aaaaaattta cttcaaaaaa
    24241 agtaacaagg tttgttgcgc tgtttttaat atctatttta gtaatgtcaa caattcctgt
    24301 atcagctgac aatagcaata cattgaatca gataaaaaaa gcagaataca gtgagacgta
    24361 taaacaatat ctaaatgatg ctaaaaatgg acgtacagaa aaatataatg ggattatacc
    24421 aaatccatat cagttggaag gtactcaaat ccaaagtaaa ggaagaacag ctccaacatc
    24481 ttatgaccct agaaaattag gtcttatgac atcaataaaa aatcaagagg atttaggaat
    24541 ctgttgggat tttgctgcaa tggcaacctt agaaagtttc ttaaagttaa ataattatgg
    24601 agactatgat ttatcagaag aacacttaag atggtgggct tcagatggtg aatatggatg
    24661 gtctgtaaat gatatgaatg gtgctttaaa ttatgaagct atgggatatt taacatcttg
    24721 gtcaggtcct aaactagaaa aagatattcc atacaatggt agagtatcta aagcacaagg
    24781 agcaaaaaaa ccaactaata tgaatacagc acctactgtt tttaatgtga cagatgctgt
    24841 gtgtgtaagt aatgacataa attctacaaa aaatgctata ttacagtatg gagcagtaac
    24901 atctggttat tatgaagata ttaaatatca aagtgatgac caaaattcat attattgtcc
    24961 aacaaaaagt tttaatacaa atcatgctat ttcaattgta ggttgggatg ataactattc
    25021 taaagataat tttaatgcaa atattagacc atcaaaaaat ggtgcttggt taataaaaaa
    25081 tagctgggga gattataatt ctgagggtgg atatttctgg atatcttatg aagacaagac
    25141 acttatgtct gatatagata atttttcaat caaaggtggt aaaaaaccaa atgatgatga
    25201 gaagatgtat caacatgact atgcaagtat tgtaccttta atttcaaaaa agataacagc
    25261 tgcaaatgta tttgatttca atagaggcga tgaaactcta aaatctgtaa tgttcttaac
    25321 tgaaagtata ggagctaagt atgaagtata ttatgctcca gtagtaaatg gtatacctca
    25381 agaaaacaat atgaaaaaat taaaagaagg tactgcccaa tattcaggat acataacagt
    25441 tccaattgat tcttttgata taccagaagg aaagggtgca attgtagtca gtatagaggg
    25501 gaaaaatgga gagtcaacta taggttctga gtcaaatgta ccaggatatg atacatttaa
    25561 agcaaaagct aatttaggtg aaagttatat catagataat actggaaaat tctttgatat
    25621 aaatagagat agtaacttct atccgtgtaa ttttactata aaagctgtta cagaaaagtc
    25681 ttctggtgag agtatcccaa atgagtcttt aattggtagt gatagatatg aaactgctat
    25741 caaagttagt caaaatggtt tcaattcttc agaaaatgta gttttagtaa atggcagttc
    25801 aatagtagat gcattggcag caactccttt tacatctgct ataaattcac caatattatt
    25861 gacacaaaaa gaagctttaa attcaaaaac taaagctgag atacagagat taggtgctaa
    25921 gaaagtatac ctaataggtg gagaaaattc tataagtaaa gaaattgaac aacaattaaa
    25981 aagcttaaat atatcgatag agagaatatc aggaagtgat agatacaaga caagtttatt
    26041 attagctcaa aagttaaatg gtataaaaaa tgtatctcaa atagcagttg taaatggagt
    26101 gaaaggatta gctgatgcaa ttagtgtagg cgctgcagca gcagaaaata acataccaat
    26161 catacttgca aatgaaaaga gcgaattgca aggagctgat gaatttctaa attcattaaa
    26221 tatagagaaa tcttatatta ttggaggaac agcatcccta tcaaacaatc tagaaagtaa
    26281 gttaaaaaat ccaactagat tatctggtag tagtagagac gaaactaatt caaagataat
    26341 agataatttt tataaaaaag atactttaaa aaatgcattt gtagttaaaa atggaatcaa
    26401 gaatcaaaat gatttaatag atggattggc agttggtcct ttaggagcaa aaactgggtc
    26461 accagtaatt ttagttggtg ataaattagc tgatagccaa aaagaagttc ttaaaaataa
    26521 gactttagaa aaagtaactc aagttggtgg aggagcaaat aaaaatgcat ttaaagagtt
    26581 agtaaaatta aaaagtgcta aatagagtac ttaagtatta acatatatta gtgtgtatta
    26641 gtaacttatc ttaataaaag ctgaaaataa ttacttcaaa ttattgataa ataagataat
    26701 caatgattgt aaagttttgt tttcagcttt aaatttatgt agtataagtt taaaaacata
    26761 aaaaagggtt actttatata gaaatataga aaatcttaca ttttatatat aaataaccca
    26821 tatttaatta actttttata gtgttctaat agatattatt gaacttaatg gtaaatataa
    26881 tgtgtaagtt tcatttaaag ttggattaga ttcatctata tatcttgagc aaagtgtaat
    26941 tgataagcta tctgcttcta taatttcacc atatagagga caactgctaa agtaagaatg
    27001 tacttcaaca tatttattta agttttcttg aacataatcg taaaaacggt tttttgtagt
    27061 agtagccata aaatcaactc ctttattttt tattaaagtt gaaactttta aaaagataaa
    27121 tatgattact tctattagaa actaagttaa aaaataagca aatagatatg aaaattagaa
    27181 taatatatta tttatatctt aattataaca ctagataata aaaaatgcta tataaaattc
    27241 agaattttcg aaagttttta agcttatttt taaatatact aataatacta ttgacattag
    27301 atagaaaaag tattatattg actatataaa ttattttagt caaactggag ggaaaagatg
    27361 cctaaatcgt attctgataa agaaagagag tatataataa aaagacttaa agaagaagca
    27421 agattgtgta tggagcaata tggtattaga aaaactactg ttgatgagct tgtaaaacgg
    27481 gtaaaaatac caaaaggaac tttttatcta ttttttcaat caaaagaatt gctctttttt
    27541 gaggtattaa gagatataca tgactctata caaaaagaaa tcttatatga gataaataga
    27601 gtagatgaaa gtattacatg tgaacaattg acagatatat ttatgaaatt ctataggatg
    27661 gttgatagta cttcaatttt aaatcttatg ataaatggag aatttgagat attggtgaga
    27721 aagttaccag attctataat tgaagaacac tttagacatg atgactttga aattggagag
    27781 attatatctt gcataccaaa tgcaaaaaat aaagacatag aaagctttag tggagcattt
    27841 agagcagttt ttcttaccat gctatataag cgcgaggttg gaagtaattg ttttgaagat
    27901 gctttaagat taatgataaa cggattagtt atacaactta tggaatagaa tttaaatttt
    27961 gtttgctaat aacttttatt aaaaattatt aacaaacaaa aaaattatat tttattgacc
    28021 atatagtcaa aatagtcaaa aatttgaaag ggtgatattg aatgattaaa gttgatgatt
    28081 tatcatttag ttatacagag agagattttt tacaaaatat taactttgga gtaggaaaag
    28141 gggaaatact aggattttta ggaccatcag gtgcaggaaa atctacatta caaaagattc
    28201 taattggaat gataactaat tatggaggaa gtgtcattgt aaatggagta gagagtaaaa
    28261 gacactcaaa taaattttat gaaaatatag gagttgattt tgaatttcct agtttatatg
    28321 aaaagttgac tgcaatagaa aatttaaaat attttgggtc tctatattct aaaaaactac
    28381 tatctattga tgagttatta aaatcagtag gactagaaaa tgaagcaaat aaaagggtat
    28441 ctgagtattc aaaaggtatg aaatctcgat taaattttat aaaagcttta ttacataatc
    28501 cagatatttt atttttagat gaaccaacaa gtggtcttga cccatcaaat agcaaggtta
    28561 tgaaagatat aattttatca gaaaaatcta aaggtaaaac tattatttta acaactcata
    28621 acatgttaga tgcaacagag ctttgtgaca gagtagcgtt cattgtaaat ggtaaaatat
    28681 ctgctttaga tacaccacat aatcttatta tgtcaaaagg agctattaaa gttagatata
    28741 cttactttga taatggagaa aaaacttctg aatgttttct gaacaatact gctaatgata
    28801 aaaatttgaa tatgcttatt gagaaaaata aacttttatc aatacatagt agtgaaccaa
    28861 cattaaatga tatttttatt gagataacag ggaggaattt acaatgaggc taaaaaatct
    28921 tattttagga gatataaagt ttcaatttaa gtatggtttt tattttttat atcttttttt
    28981 aagtattata tatatttgta ttatcaatgt atttccaact tttatgagag aaaaaatagc
    29041 tataattatg atttattctg acccagcagc aatgggattg ttttttatgg gagctattgt
    29101 acttcttgag aaaagtcaaa gggttttaaa ttccttagct gtatctccag taaaagtatc
    29161 tgagtatatt ttatcaaagg taatttcatt aggagtaata tctagtattg tagctatgtt
    29221 tattgctatt acattaaatt tagataatat tataatatca actataggta cctttttttc
    29281 ttctattata ttttctttgc ttggattgat acttgcaagt aaagcatcta gtttgaatca
    29341 gtttattgtt ttaagtattc ctattgagat tatatgcttt attccaccaa tactcaatgt
    29401 acttcttgac acaaaatcat atgcaaattt gtaccctttt aatatatgta tttctcttat
    29461 tagtggagat aaaaatttta taatgattaa tattttaatt ttaatatcaa ttataataat
    29521 aatttatttt ataacttatt attttatttg tagcagttgg aaaaaggtag gtggagtaaa
    29581 actatgataa agattataaa tgcgtttaaa caagagtttg aacaaattaa gagagatgct
    29641 atgcttttta tagtatgtgt ttctccaata ttatgtggag tatttataaa atttggaata
    29701 ccattaatac agaatatatc acttaacaag ttttattatc aattaaattt agagccgtat
    29761 ttcttgatgt ttgatttact tttagctttt attacacctt ttatgttctt ttttgcttct
    29821 acaatggtca tattgggaga aattgatgac agcatttcaa gatatttaat agtaactccg
    29881 cttggtaaaa ctggttatct tatttcacga tttggaatac caggtatctt agcatttatt
    29941 attactatga ttctacttat ctttttttct ctaactaaaa tttctttctt gttaaactta
    30001 tcaatttctt tattagtttt attacaagga attattatat caatattagt gatttcttta
    30061 tcatcaaata aactagaagg aatggtaatt acgaaattct caggtgtttt tatgatgggt
    30121 attttagcac cattttttat tttaaataaa gcacaatata ttctgttctt cttaccaact
    30181 ttttggatat cgaaggcatt taaggaagat aattatgtct atatgtttat ttcaattgtt
    30241 atatcattaa tatggatttt attattattt aaaaagttta gtaaaaaaat agttaaataa
    30301 gaaaatttaa tatataaatg taaggttgac ttgacagtaa tgttgaaaaa tgttacattt
    30361 aagatgtaaa gttaacctta catgaatgga gcaaatatga aaaataaaat aaagatatta
    30421 agagaaaaat taggattgac acaagaacaa ctagggagat tagttggaac atctagacag
    30481 gctataaatg ctatagaaac tggtaaaaat gaaccttcaa tatggttggc atatgatatt
    30541 tcaagaattt ttaatgaacc aattgaaagt gtatttttat ttgaagaaag tgaaagaaaa
    30601 tcaagagcac agataagtag gggagaatat tatggctata agaaagataa gaacatttga
    30661 tgatgaaatt ttaagaaaaa agagtaagta tgtagaaaac gtagataata agataagaga
    30721 aatattaaat gacatggcag agaccatgta caatactcca aatggaggag gattagctgc
    30781 atgccaagta ggagtattaa agcgattagt tgttatagat ttaggagaag gacttattaa
    30841 gcttgttaat cctgaaatta ttaaacaaga aggggaacaa attgttgttg aaggatgttt
    30901 aagttttcct gaagtatggg gtaaattaaa aagaccaaaa aaagttacag tgcaagctct
    30961 aaacgaatac ggtgagaaaa tagaaattaa aggttcaggt tttatggcaa aatgtctttg
    31021 tcatgagata gaccatttaa atggtatagt ttttacagat aaaattattg aacatgtaaa
    31081 attgtaagat agattggtta ttgaatttat aaaatatttt atagtaagga gttaaattat
    31141 gagattatgg cataaggatt taattgatgt attacctaaa aatcaattag taagtcaatg
    31201 gagagagcta cttgctataa aaggttctat agataaaaaa ggtactccaa accatctatt
    31261 agtgaataaa gtattgaatt atagtataga tgaatttaaa ttttatacaa aaattgtaca
    31321 tgatgaaatg ttaaaaagaa attataaacc taatgaactt aaatatacaa gtatattaaa
    31381 atggaaaaat agaaattttg caaatgatat atctaatgaa catagtttaa atttagaaaa
    31441 tttatatgat gattggcata ataaaatgta tttaaagcaa tgcttatata atttagaaga
    31501 aaaagcaaca tgtggaggaa taccaataaa tgaatggaat atattacttt gtaaatatag
    31561 taaagattat gaattgtggt ctggaaatat catgttttaa ttactataga ttaacattat
    31621 agtattattg tatataaaga ggtgattatt tgtataataa aataaaatat attccaataa
    31681 attgtgaaat agcttgtaat aaattaaaaa ggagtatgcc atataaatgg gatttaaata
    31741 tttatcgtgg atgtgagcat ggatgtaaat attgttatgc tatttactct cataagtaca
    31801 tcaactccaa taattatttt gaagagattt atgtaaaaac aaatatagta gaaaaacttg
    31861 agagacaact taaaagcagt aaatggaaga aagaagtaat caatatagga ggagttacag
    31921 atagttatca accaatagaa gctgactata aaattatgcc agaaatatta aacctgctaa
    31981 taaaatacaa gacaccagct attatttcta caaagtcaga tttaatttta agagattacg
    32041 atttaattga taagctatct aggattacat atatcaatgt agcatctaca attaccacag
    32101 taaatgaaga tacacaaagg cttattgagc caaatggtgt ggattcaatg agacgattta
    32161 aaatgttaaa agaatttaga aaaactaacg catcagttgg tctacatatt atgccaatta
    32221 taccatatat tacagatgat tttgataata taaattcgct atttagacat gcaaaagaat
    32281 gtaatgtaca ttatgtttta cctgggactt tatacttaag gggtataact agaggtgttt
    32341 tttttgactt tgttaaaaaa gagtttcctg aattatttga taaattatca atactatata
    32401 gtgaaggttc acttaatagg gagtataaaa atcaattgta taaaatggtt aatgaactta
    32461 gatataaata ttctctatca agcagttact ctaaaataat gaaggaaaag ttaaaaaact
    32521 caggagatgt acagatatct ttttttgatt agttttatat aaaaaaattt tttttactat
    32581 gatgattaaa atttattaaa attaaaattt attgacaaat ataaaattta aatatataat
    32641 taattcataa aataaaaata tgaaaggatg atgttgttcg gtgatatttg atatcataaa
    32701 atcgttgata taagtattgc tggaaaagag tgaataaaat caaatttaat aagcaaacaa
    32761 agtaaagcta tagttttatt gttgtgctta aaaatatttg gttctatttt actcttattt
    32821 aaactcatct ttttgaagtt aaaccacaga gtaaactctg tggttttttt attttaaaaa
    32881 taaattttaa ggagtggtat gttttgttaa acaaattatg tatgtattta gaaagaccag
    32941 agctttataa acaaagtgaa attaattttt gggatgatga gtatatttca gagcaattat
    33001 taaaagcaca cttagacact aattttgaag gagcaagtag aaattttaac tttatcgagg
    33061 attctgtaaa ttggatagtt acagttgcaa atccagttaa ttatcctaaa ttacttgatt
    33121 taggttgtgg tccaggttta tatgcagaga aatttgcaca aaaaggttat aaggtaactg
    33181 gaattgattt ctcaaaacgt tctattaact atgcacaaaa tagaaataag gagactaatt
    33241 taaatataaa ttacttgttt caaagttatt taaatatgaa ctataatgag gaatttgatt
    33301 tggctacctt aatttattgt gattatggag ctttgtcaac tgaaaataga aggttattaa
    33361 tggaaaaaat ttatgatagt ttaaaacctg gaggaaaatt aatattagat gtatttacaa
    33421 taaataaata caataatttt gaggaaatta aatattggga aataaatgaa gatggaggat
    33481 tttggagtaa tgaaaaatat atgtgtctac aagataattg taaatacaat gattataata
    33541 cattagaaca aactcttgta ataaccgaaa aagatgaaaa tgtattttat gtttggaatc
    33601 actatttttc aaaagaaagt ttcttattag aagttgaaaa tattggattt aagtctgttg
    33661 agttttttag taatgttaag ggtgaagcat attctgacga tagtatgact atgggattag
    33721 ttttacaaaa ataataattt ttttaaaatg aataaataaa aacttgaaac ctttaacaat
    33781 aaaataacat aagaaaagct tacatattga aaaatggaaa cttttatgtt atttttagta
    33841 cattacaaat ttgtttatat aaaaatcaat acttgaatta ttatttttat gtgaaattta
    33901 tctatagtat atttttataa acaagtaatg ttattaaaat taagtatata gttaaaagtg
    33961 tatagcaaaa aggctgttat attaatgtta gaggttcagg gaaaatatat aaagcaaaga
    34021 tatttacaga taatgtagat tgcacagcta taagttagat aatagaatta tgtaatcaag
    34081 aatttacaac aaagtataag ataaggataa tgctaaattg ccatacaggt gctagatgtg
    34141 taaatggatt taattaatac tattgataaa gtgcaacaag cacataaacc aattgatgag
    34201 attattgaaa ctataagaga tatagttgac ataattaaaa tattggaacc tgtttataat
    34261 tttaaatcaa atcaataatg attaagatta aaataatatt aaggcatcaa tgttataaga
    34321 gtacaatata aggagtacta tatagtactc cttacttata catattaggc aatagggaat
    34381 ttttttatag ttaaattttc aaatattttt tagggaactt tataattgag aattaagggt
    34441 atagtatgtg atgaacttac taaatttata attaggttat ataatggaat aatcatcaat
    34501 agttttactt tagggaaaat atatgcttaa ggaagtatag cttactaata ttattaaaat
    34561 gtatatttaa aatgataaaa aaagaattag acaagtattt agtaaattga ctatgcaaaa
    34621 ttctatcaag caggaacact atgactttag tcatgggagg ttcagtaggt aacttgttga
    34681 attaagttta tattatttaa ataaactact taatttagat aatataaaaa gtcagaattt
    34741 taagaataga gctatataat cttagctatt aggagaagta ctatgatagg aatatatttt
    34801 agtggaacag gaaattcaag atactgtgta gaaaaatttt tacaagaata tgatataaca
    34861 gcaaattctt attctattga agataatgaa cttttacagc acatcaataa tcatgagaat
    34921 attattttta gttatcctgt gcaatatagt aatgtgccaa aaatattgaa agattttata
    34981 ataaatcatt caactttgtg gaatggtaaa cgtgttttta ttattgcaac tatggctcta
    35041 tttagtggag atggctctgg tgtgttagct agaatattaa aaaaatacgg tgctataact
    35101 gttggtggat tacatgtgaa gatgccagat agtataggag atgaaaaggt attaaaacat
    35161 tctttagagt ataatagaaa gcttgtaata aaagcagaaa agaaagtaac taaagctgct
    35221 aaaaaactga aacatgggtc accaccaaaa gaagggttgg gttttttgag tcatattgta
    35281 gggttatttg gacaacgatt gtattttatc aataaaacaa atatgtatac agataaacta
    35341 aaaattaata ctgaggaatg tattgtatgt ggtaaatgcg ttaatttatg tccaatgaag
    35401 aatctagtaa ttaaaaattg tatgattgtt gcaaatgggc aatgtacaat gtgttatcgt
    35461 tgtgtaaata attgtgccaa aaaagcaatt acattgttag gtaaaaaagt tgttgaacag
    35521 agtaatatta aaaaatatat gtaagaaatt taaagtttta ttgaatgtaa attgatgtat
    35581 attttatgtt agaaagagag gttaaataat ggaatactac atagttgatt catttgcaac
    35641 taaactattt aaaggaaatc ctgctggagt ttgtgttctt gacagaagaa tacctttaga
    35701 gttaatgcag aaaatagcag aagaaaacaa tttaccagaa acagcatttg tagttaaatg
    35761 taaaggaaat tatgaattac gatggtttac tcctaaagca gaaattgatt tatgtggtca
    35821 tgcaacttta gcagcagctt atgtaatatc aaattttatt gatgttaatg taaaaaggat
    35881 agatttcttt actcaaagtg gaaagcttga agttacacga aatggaaatc tatatgaaat
    35941 gatatttcca gaaataatgc ctattgaaat agagttatca ccacaacaag ctaatttgat
    36001 aggctgtgta ccaagtgctg tttattcttc aagagattta atcttattgc taaacagtga
    36061 acaagaagtt ataaattata aacctaatta cgcacaattg cgtaaattga cagactggtt
    36121 aggtataata atcacagcac aaggaagtaa tacagatttt gtatcaagat atttttgtcc
    36181 agaattagat tcagaagacc ctgttactgg ttcatcacat tgtaatctta ttccatactg
    36241 gtctgaaaag ttgggaaaac acaaaatggt agctgctcaa ctttctaatc gtggtggtat
    36301 aattcagtgt gaagtgttga aggataatac tgtaaaaatt tctggtgaag cagtcttgtt
    36361 tatgcaggga acaataaaga ttgatattta aataagtata ataactaatt tattatgaaa
    36421 aataattaat tttcttagtg ttaacaataa taaagtagag ttaaaaagct tgatttcact
    36481 taaatcaata tgatagatgt tgatactaag attgacaagc atgattaaaa aagataatat
    36541 ttaatctata aagataaaaa cacagtctgg ttggtagtcc agacgcagca atagctgtca
    36601 gtaacctgcc tccttggttg tccgttcttt agaaagtaat ttaaggagga actagcaatg
    36661 gacaaaatta gtggaaaatt aacagtttta tttgaagaac cattttgggt aggtatattt
    36721 gaaagacaag atggtaaaaa atatgaagca tgtagggtag tttttggagc agaacctaaa
    36781 gaagtagaag tgtatgaatt tatacttgaa agatttttct cattagattt tggtagcatt
    36841 aaattagaaa aaaatgtgac caaagacaac attggataca aaagaatgca gagaaaagta
    36901 aaaaaggaac aagaaaaaga aactataggg actaaggctc aaaatgctct taagcttcaa
    36961 tatgaagaaa gaaaacagga tagaaaaaac ctagctaaaa atagaaaaga agaagaaaaa
    37021 gaaagactat ttaatttgaa acaagaaaag agaaaagcta aacataaggg tcattaattt
    37081 taattaaata tctttttaat aattgctaga aaaaggtgta taaaattttt aattttatac
    37141 accttaattt attgaaaaga ataaggtttt atatttcaat tactttaaaa tataaaaata
    37201 tactaataaa aattgtaaaa atagtataaa tggtatacca aatgtaaatt taatgtgttt
    37261 agttttatgt ctaaaagaat acattccaat tatagaacct atactacctc caattactgc
    37321 tatagacata agagtagctt cttttattct ccattcgttt ctaattgctc ttttcttatc
    37381 tatgtacatt gaaaagaaag caatagaatt aatcactata aaatatatta gaataaaatt
    37441 tttcacagtc ttgcctccat aaaaatatat tatacattat aaaacaagat atttgttttg
    37501 gaaagttaaa tttgtaatta gtacatataa aatatttgat aagaacaaat ataatattaa
    37561 ttggaaaatt taaaaaaatt aaacaattag caaatagggg gtatatttat aagacacaaa
    37621 gtgataaaat ctatttagaa aataatgtaa aataacagga ggataaagca aaatgaaatt
    37681 tatagtagaa aaagaagttt ttgataaatt agaaaatgta tgctttggtg tagtagttgc
    37741 aaaaggaata gataatacta aagaaataga aagaataagc aaccttttag atataagtat
    37801 agatagagta gaagattact tcaaagataa aaaagtaaag gaatcagaag aaattatacc
    37861 atatagagag gcatttagaa gtctaggcat gaacccaaat aaatttatga gttcgataga
    37921 agcaatgaca acaagggttg ctaagaataa gaaacttcct catataaatc ctattgtaga
    37981 tttaggaaac tctatttctt taaaatattt acttccaatg ggtgctcatg atatggattt
    38041 tagaaatgat gatgtatatg ttagattttc taaaaaaggg gataaatttg taccatttgg
    38101 agaaactgat gttgaattaa tggaagaagg agaattaatt tattcagttg gagacatggt
    38161 aaaaactaga agatggatat ggagacaagg agaggaagga aaaattacta atagctcaaa
    38221 aaatatattt tttcctatag atggttttac tgatgctaat ttagataagg taatgagtgc
    38281 aagagaagaa ttagcaaaat tgttaaagga aatatttaat tgtgaaatta aagtaggttt
    38341 tgtagataaa gataatcctg aaatggaaat ataataagtt gttgaatact tgttaagata
    38401 ttatatttac ttaatgatgt taaaaaggta ttaaaaaaga aaggtcgtag taaatttgaa
    38461 aaaaactata ataaagaatg taaatccaat gattgaaaat aagtttatag gactttttga
    38521 aatagagtat aaaaacaaat tagatgaaga taaggtttgg atggtagcat caagaaaaag
    38581 tagtgagcaa ttaaaaaata tttatttgaa gaatgaagaa gatagtgtag atgcagttgt
    38641 aatagttggg cttcataaaa gtagtaaaaa attaatttta ataagacaat ttagagtacc
    38701 tattaatgga tatatatacg agttaccagc aggtcttgtt gatgaaggag agtctataga
    38761 tatttccgtt gaaagagaac ttagagaaga aacaggactt actcttttag aaattaaaaa
    38821 aaataaaagt attgataaag tttatttatc tcctggaatg agtgatgaat ctgttgcctt
    38881 tgtttattgt atatgtgatg gtgatataac agatgaattt ttagaaccag atgaagagat
    38941 tgaagcgctt ttaatttcgc aagaagatgc aaaagagatt ttacaaagta atcataagat
    39001 agacacaaaa gcatttttga ttttacaaat gtttgtgagt ttaggagcta aattatttga
    39061 atagatatat agaaaagagg ttatatagaa gagtaaaata ataaagttta ttttacttgt
    39121 ataaattata atctcttttt ttatacaata aagtataatt ttgtgtattt ttaaataagt
    39181 gacttgactc ttaaattttc ataatatgtt ataaaccaat ttaagatact acaataatta
    39241 aaattccaaa attatttaac atatttgcaa ttaaaatgag aaaaggtaaa ggttgaatga
    39301 ttgaaaaatt tgatgtaaaa tagtagctta gtttaatatt atagtttgta gggttaaaaa
    39361 ttagaaattg taagggagat aaattctatg aaaaaattag ttattatttt aattagtatc
    39421 attagtatgg ttagcttgac agcttgtaaa aaaagcaatg aaagtaaata taataattta
    39481 aacaacaaag aatccggaca aacaaccatt gaaatggact tagataaaaa ttatgatact
    39541 tcagacccat ttgttaatgc acgtttgttt tgtgtgtcta atgatataga tgttttagac
    39601 acagagattt cttttaaaat ggatggagat agtggtattg tggaaataaa ggacaataaa
    39661 acatatgaaa ctttatggag taatacatgg catggaagcg ttgataatga tacattcaca
    39721 atttctcttt ctaatataca aaaagagaaa gagtatgcta tatgctttac tggaattaaa
    39781 ataaatcatg cagttgtaaa ggttactttt gaaagcaatt tagttaagga gaaagaaaaa
    39841 ccctcaaaat aaattccaga ttgtctataa cttgatattc agtacataaa agcagttgat
    39901 atttatgatt gactgctttt tcttatcaaa aaggagagtt tgtgcatttt tacttgaaat
    39961 agtttatgca catcaaaagt tggtgagcat gatattggaa atggtaagca tgaaatcttg
    40021 ataagacaag gaaataaatt taagttttca attaagtata tttccataat ttagttaaca
    40081 ataagctaat tattatttat attttgatat ataaataata attgtagcaa atttcaaaaa
    40141 atcatatatt ttttgaacta aataaaaatt tatttttatt attttaaatt agaggagatt
    40201 cttgaagata tattattttt aaaaataagt atagtttaaa aattcaaaaa aaagatggca
    40261 aaatatgtcc caagggacat tgagtaaaat aaatgatttc agcttattta cactaaaaag
    40321 tacatactaa atgaggggta aaataaagaa aaatgatata ctaattgtct tttgataata
    40381 aaaaaacatg gaatttgatt atttaatcaa gaaaaagtat tgaacaaatg atttatttag
    40441 tgtacaataa tcatgtaaaa acatagtaat ggagggagac atttcataat gaaaattaag
    40501 gtaggaatga acggatttgg aagaatagga agagctgtat taagaatagc tcaagaagaa
    40561 ttaggagata atatagaaat tgtagccata aatgcaagag caacaacaga atctttggca
    40621 catttattta catatgattc atgctatgga acttttagag gtgaagtaga ggcaaaggat
    40681 gaagacactc tagtagtaaa ctctaaagag ataaaaatat taagatataa tgacccagaa
    40741 gaattaccat ggaaagaact gggggttgat atagtaatag aatcaacagg attatttaca
    40801 caaagagaaa aggcagaaaa gcatattaaa gcaggagcaa aaaaagtaat tataacagct
    40861 ccaggaaaaa atgaagatat aactatagtt atcggagtta atgagaaaga atatgataat
    40921 gaaaagcaca atataatttc aaatgcatct tgtactacaa attgtctagc tccttttgct
    40981 aaagtattgg acgaaaaatt tggtatagta aaagggttaa tgactacagt acattcatat
    41041 actaacgatc aaagaatatt agataaaagc cataaagatt tgagaagagc aagagcagcg
    41101 gctgaatcta taatacctac cactacagga gcagcaaaag ctgtgtcaag agtactacca
    41161 caattagaag gaaaattaaa tggtttttca cttagagtac caacaccaac agtttcactt
    41221 gttgatttag tgtgcgaact taaagaaaac gttacatctg agcaagttaa ctctgtgtta
    41281 aaagatgctg ctgaaggaga attaaaaggt gttttaggat attgtgacaa gccacttgtt
    41341 tctatagatt ataaaggaga ttcaagatca tctattatag acgctctatc cacaatggtt
    41401 atagaagaca atatggttaa ggtagtttct tggtatgata atgaatgggg atattcttca
    41461 agaactgttg acttagtaaa atatgtagct gaaaaattaa aataatatat atttcttaaa
    41521 gcaaatttta aaaaaatttt ttaaaaaaat tatataaaac taaaaaaaaa gattatgaaa
    41581 aatattgaag gaaaaatttt ttcataatct tttttctttc atgcaaaaag atacaagtta
    41641 caacttatat ttgcatatta ggtcgttaga gaagtatata tatatttagt aaggaatcat
    41701 actttttata aaatgaaaga taagatgtcg aaaacttgca taaatctgaa aaatttttat
    41761 tattaaaata ctgatttcca ttttaaaaat gataaaaaaa tgacaaataa agttgcaaat
    41821 agtaatactt ataagtataa ttaaaaaaga gaaaaggttt tgttaaactt tataacaaaa
    41881 aaagaaggga tgattcaaaa tggagaagtt aacagacagg agacaggtta aggcagtaag
    41941 catggaaacc ttcattttcc taatattact agtagttggt tttgggtatg ttggtagtat
    42001 tatgggagca ggaatgatgt tcaaagtaat aatgagtaca gcacatgctt tactattgga
    42061 gacagttttc ttaattatgg ctatggcagt tcttgcaggc gcattaagcg cactactttc
    42121 agagtttgga gtaatagcgt taattaataa aattttcgct gtatttatga agcctttata
    42181 tggactacct ggtgctagta tagcaggagc tataacaact tatttatcag ataatccagc
    42241 tattatacct tttgctaaag ataaaacatt cacacagtat tttaaacaat accaagttcc
    42301 agcattatgt aacttaggaa cagcctttgg tatgggactt atcttaacaa catttatgat
    42361 ttctcaaggt acagaatatg tacttccagc attaattggt aatttaggtg caattatagg
    42421 tagtgtcata agtgttagaa taatgttgac atttactaag aagttttata aatacagtcc
    42481 ggaagaagat aaagcaacag gaacattaga gaaaaaggat gaatttagag aaatcagaga
    42541 aggaaatgta tttcaaagag ctttagatgc aattcttgaa ggtggtaaaa tgggggtaga
    42601 tatgggaatg gctataattc ctggagtcct agtagtatgt acattggtga tgttattaac
    42661 ttttggacca tctacagacc ctgttacagg tcaagaagtt tatacaggag ctgcatatga
    42721 aggaataaaa ttacttccag ttattggaga taaacttgga tttatattag aaccattatt
    42781 tggatttaca tcaccagagg caatagcatt ccctataact tcattgggag ctgttggcgc
    42841 agcaatgtct ctagttccag agtttataaa gtcaggagct ataactccta atgatatagc
    42901 agtatttaca gctatgggta tgtgttggag tggatattta agtacacata ttggtatgat
    42961 ggatgcatta aatgctagac agttggcagg taaagctatt ctttctcata caataggtgg
    43021 tttatgtgca ggagcagctg ctcactttat atttacactc gtaggataaa tgtaatcagc
    43081 taagataaaa aataatatac aaaaaatggt tgttgatatg taataagaat ttacatatca
    43141 acaaccattt ttttctgact aaagataatt tataatacat aaacattaag tggatattag
    43201 agttaagtta tatttatgta aaaagtaaca aaaatctgta gaaatttatg acaaaattta
    43261 gtacactaac tatatgttct tatttaaaat ttaaggttag aattaggaat tacctagtag
    43321 agtaagcttt gattaataaa agaatcataa aataaaaata ttagtcataa agattataaa
    43381 taacttactt aaaataaagc catagaactt acaaaaatta aaaaagcata taaatatgga
    43441 ggggtacaat ggatgaatta tttcatatag gaattgatgt aggttctaca acggtgaagg
    43501 ttgtggtact taataatagt aataatatag ttcataaaga atatagaaga cattattctg
    43561 atgtaaaaaa atcagttaaa gaagtactaa atggtatata tgaaaaattg ggagatataa
    43621 atactaccat tataataact ggttcaggtg gaattggaat atcaaaaaaa ttaggtgtaa
    43681 aatttgttca ggaagttata tctagtacaa aatcaataga gtattttcat cctgagactg
    43741 atgttgtcat agaacttggg ggtgaagatg caaagataac atatctaagt ggaggaatag
    43801 accaaagaat gaatggaata tgtgcaggtg gcactggagc attcatagac cagatggcat
    43861 cactcttaaa gacagatgcc agtggattaa atgaacttgc taaagggtat aatgttatat
    43921 atcccatagc ttcaagatgt ggtgtttttg ctaaaacaga tattcaacct cttataaatg
    43981 atggagccaa tcagactgat atagcaatga gtattttcaa tgcagttgtc gtacaaactg
    44041 tgagtgtcct ttcttgtgga agaaaaatag aaggaaatgt tgcgtttttg ggtggtccat
    44101 tgtacttttt atctgaactt agagaagcat ttaaaagagt attagattta aaagatgaaa
    44161 acataatctt cccagaaaat gcacaacttt atattgctat tggagcagga ttattatcag
    44221 tagatgaaga taatatacaa ctaaaatctc taatagaaaa attggatagt ataaagaata
    44281 ttgaagatgg agaagtaaat ttattagaac ctttatttaa agataaaaat gagtatgaag
    44341 aattttcaag aagacatgaa aaagaaaaaa taaattatgt ggacataaat tcaataaaaa
    44401 gcaattgtta tttaggaatt gatgcaggct caactacaac taaagcagca cttattgatg
    44461 aggatggaag acttgtatat tcttattata atagcaatga aggaaatcca ttaaaaacaa
    44521 ccattaaagt tataaatgaa gtatatgata tattaccaaa aaatattaaa atattgagtt
    44581 caactgtaac tggatatgga gaaggtctta ttaaaaaagc tcttaaaatc gataatggag
    44641 agatagagac tatagcacat tacaaagctg ctaaattttt caacaaagat gtagatttta
    44701 tacttgatat tggtggtcaa gatatgaagt gcctaaaaat aaaagatgga gtaattgata
    44761 atataatatt aaatgaggct tgttcatcag gttgtggctc atttttagag acatttgcaa
    44821 gttctttatc tatgacaata gaagaatttg cgcatgaagg tatttattct caaaatcctg
    44881 tagatttagg ttcaagatgt actgtattta tgaattctag agtaaaacaa gctcaaaaag
    44941 aaggtgcaag tgttggagat atatcagcag ggctatctta ttcagtaata aaaaatgctt
    45001 tatttaaagt aataaagatt agagatttaa atgagattgg taataatatt gttgtacaag
    45061 gtggaacctt ttataatgat ttggtgctta gaagctttga aaaactaatt ggaaaaaatg
    45121 taattagacc taatatttca ggaattatgg gagcttttgg ttcagcactt atagctaaag
    45181 aaaaatatga aagtggatac aaaacatcct tgttatctaa ggaagagttg aataatatca
    45241 agctagaagc aagtgtaact agatgtaaag gttgttcaaa tcattgtctt cttacaataa
    45301 ataaattttc tgataatgaa atttttattt caggtaatag atgtgagaag ggtgaagcta
    45361 tttatggtga taaaaaaata ggattagaaa agaaaaaacc aataaattta tttaagtaca
    45421 aatacaatag aatttttaga tacaaaccat tggaaaaaga agaagcaaaa aatggggaaa
    45481 tagggatacc aagagtatta aatatgtatg aagattatcc attttggttt acttttttca
    45541 atgctatggg ctttagagtt gtactttcag ataggtcatc aaaacagtta tatgaaactg
    45601 gtataactag tattgcatct gaaacagttt gttatccagg aaaattagtt catggacata
    45661 tagaaaattt aattgcaaaa ggtataaaaa atatatttta tccaagtgta acaaatgaaa
    45721 ataaagagga ttcaaatgca gataattatt ataattgtcc tgttgtaata tcatattctg
    45781 aagtaataaa aaacaatgta gagaatataa gaaataagaa cataaattat ataaatccat
    45841 ttataagtct aaatgataag gaaaaattga agaaaagact ctatgatgaa ttatcaagac
    45901 atttttctga tataaaaata actaaagaag aagttaatca tgcagttgat aaagctactg
    45961 atgaacagaa tttatttaaa atggagatac aagcagcagg tgaaagagca cttaaagaaa
    46021 taaaagaaag aaatatgaag gggattgtgt tatgtggaag accatatcat atagacccag
    46081 aaataaatca tggaatgcca gagcttataa attcattaga tatggcagtg cttactgaag
    46141 actctatatg tcatttagcc aatgtacaaa gaccacttag agttgtagac caatgggtat
    46201 atcattcaag attgtataaa gcagctagtt ttgtaagaga taaaaactat ttggaacttg
    46261 ttcaacttaa ttcatttggc tgtggattag atgcagtaac tacagaccag gttcaagaaa
    46321 tacttaatga aaaatcgaag atatatacta ttataaagat tgacgaaggc aacaatttag
    46381 gagcagctaa gataaggatg aggtccttaa aagcagctat gtttgagaga gaaagcaaaa
    46441 atatagatgt aaaaaatata aaggtaaaca ggatacagta tgctaaaaat aatcagataa
    46501 cgaacaaaca tactatatta gcaccacaaa tgtctccaat acatttccaa ttccttgaaa
    46561 aagctgttaa cttaagtggt tataatatag aaattctaaa agatactgat agtagtgtaa
    46621 ttgaagaagg gttaagatat gtaaataatg atgcatgtta tccagctata atagttgtag
    46681 gtcagctaat aacagcatta aaatctggca aatatgattt aaataacact tctgttacta
    46741 taactcagac tggtggaggt tgtagagcta caaattatat tggattctta agaaaggcta
    46801 tatacgatgc tggatttaaa gatgttcctg tcattgcact tagtgtaaat ggaatagaag
    46861 atagtggtat aatggataat atatcactaa aattaatcaa tagactcttt atgtctgttg
    46921 tttatggtga tttgctgatg aaagtactat atagagttag accatatgaa aaagttactg
    46981 gaagtgcaaa tgctctatat gaaaaatggg ttgatatatg caaatcttct cttgttaaag
    47041 caaaaatttc tgtatttact agaaatataa aagatatagt aaaagaattt gataatttag
    47101 agatactaga tatcaaaaaa ccaaaagtag gtttggttgg agaaatattg gtgaaattcc
    47161 atccaattgc aaataataat ttagtagata tattagagcg agaaggtgct gaagcagtcg
    47221 tgccagacct tacaaatttc ttcttaagtt gtgcctttaa tactatatac aaacacactc
    47281 atttagaagg aagtagaaag agtagaatga taggagaggc atttatatac ataactggaa
    47341 tatatcaaag agtatataaa aaagcacttg ataagagtga gagattttat gctccagcca
    47401 atataaaaaa tgttgctaaa agtacagaac cagtagtgtc attaggtaat caaactggag
    47461 aaggttggct tttaacaggt gaaatggttg aattattaaa tgaaggtgta gaaaacatta
    47521 tttgtatgca accttttgga tgtttaccta atcacataat tggtaagggt tctataaaag
    47581 aattaaagag gttgtataaa aatgcaaata taatacctat tgattatgac ccttctgcaa
    47641 gtgaggtaaa tcaacttaac aggataaaac ttatgctttc taaggctttt aaaaatatat
    47701 aagatttata ttttgatatg ttaaaagtta atgaatttaa aaatatactc tatattaagt
    47761 atctataaaa aagagttatc ctatttttta gggtaactct ttattagtta aaaaattata
    47821 tgtatactga tattaaaggg gggaagtaat atgagtttag tatatgatgt ttataaatca
    47881 aaattaggaa atttgtacat attaagtgaa gatggtttta tagttagtat atacatagga
    47941 gatgaaaaat ttaataattt aaaaaatgaa tgtattaaaa aaggaattga tataaagaga
    48001 agtaaggaag atttaaagga agcaataagc cagatagatg attactttaa tggaaaaaga
    48061 aaagtcttta atttaaatat tcgtattgaa gggactgaat ttcaaaaatc agtttatagg
    48121 gaaatgttaa aaatacctta tggagaaaca ttgtgttatt cagatatagc aagaaatata
    48181 aacaatccaa aatcagtaag agcaatagga caagcaagta aaagtaataa aattccaata
    48241 ataatacctt gtcatagagt agttggcaaa aaagatattg gtggatatat ggggaatcat
    48301 tctgatttga aagagatact attaaattta gaaagacaga gttaacttag aaagaaatgt
    48361 ttttattgtt aatatttgat ataataatag taaaaagaag tattttttac aaaaacaatg
    48421 aagaatttat tttaatttac aaaaatgagg gggaatttta atgtgtgata aagttatagc
    48481 atcaaaatat catgagaagg gatttaattg tgcagaatca gttataaaag catataatga
    48541 ggaatttaat acagatatac cagtttgttt aggaagtgga ctgggttcag ggtgtggggt
    48601 tgctagttta tgtggtgcag taaatgcatc aaatataata attggatatg taaaaggcag
    48661 aaaccacgaa gatgaaagta ctaaagctaa agtatatgct aaagatttaa ctacaacagt
    48721 aagaaaagag tatggttcag agttatgtat agacctaaaa aaagatttag ttgcttgtag
    48781 agaaataatg gatttcgcat atgatagtct aaaggaaact ttaaaaaaag aattataaga
    48841 aaataagcta tcaaatataa attatttgat agcttatttt tatagccgat actaaataaa
    48901 tcaaatatat tttagaatta ttatttgtaa ataaacagca aataatttta ggctttttat
    48961 ttaatatagt ttttatttat atttattttt gaatatgtta tactttgttt aaataaatat
    49021 ttgtaatgag ggagatgaga agattgaaga atctcaattt acttattaat aaattatatt
    49081 caaaaaatca taatgaagca tataaaactt ttttattctt agaaaatgaa agtttaaaat
    49141 caaatattac atattgtttt tttgactcat tcctagaaat gattgataac gaaaactcat
    49201 atattcgaac aaggggattg ttattaatct ctgcaaatgc tcagtgggat attgataata
    49261 aaattgaaat aaatatagat agtatactaa gtcatatcgt agataaaaaa ccttctgtat
    49321 caagaatgtt tattaaatcc atacctaata ttacaaagta taaagaaaat cttattaatc
    49381 gcataaaaat ggaattaagt aatgcagata taagtattta taataataat atgaaaccat
    49441 tagtagaaaa ggatataaac gatacattat ctaatattag ttaaatatta atatagaaat
    49501 tgaatattat ctagttacaa ttatttataa ctaagataat aaaacaacaa tggtgctaat
    49561 ttatatgtat aaattaatta tgaaaaattt atataagtaa aatatattaa cataaaggta
    49621 aaattttgta tactaaaagg gaatatttac agtttaatgg cagttttaaa ataataaatt
    49681 aaagctgtca tttttattta aaaattttta gaaaaagtac aatagtgtta atgtgtgaat
    49741 tagataaggt gtatataata gtttagatga tatgatataa aatatgttgt aaattaaatg
    49801 ttttctttga caatatatac acaaggatga taatatctat atgaataaaa gatagtgtgt
    49861 aatttgataa tatgtaatta taacattatg atataattac aataaagtat gtaataatct
    49921 gtagaaattt caagctagtt atctaagttt tcggataact aaatctaaac ggaatacata
    49981 atgtattaaa taaatgatga tactaaaatg atactatttt tatagaaatt tattgaggta
    50041 tataattaat gaaaataata tattaaatta tataaattaa attatataat atattgagtt
    50101 ttacataaaa gcaaaggtgg gaataaaaat gaaagaaatt gctgatgcta taacatcaga
    50161 gtatttaagc tatggtatca atgaagatat tagtatctat gaaggtagat tttgcatata
    50221 tttagataaa aaatatagat gtaatgggaa aatttattat aaaatgacac ctccaatatc
    50281 tataagtttt aaagcagaca taggttgtgt tgaagagata gacaatgaag atgacaattt
    50341 agctttagat tatgataatg ctattcttga agttcatgga tataaaatta tttctataac
    50401 aataaatact ttaagtgaat ttagtgtaga aggttatatc aatgatgact gtataaaatc
    50461 taagaactcc tatgttgaat atgtagattt taatataata aacttagata aaatacctgg
    50521 aaaactcatt aaatacaatg ataaggtata cgcaggtaga attgaatttg atataaatga
    50581 ttatgttgta actatagaca agcgatatga ttatagaaaa gaattaaaat cagaattaaa
    50641 gtctaaatct ggagcaataa taactcatat aggcaggatt agaagaaaag atggtagaat
    50701 ttttagaaca aataatacaa taaatctttt agataggata tcaacagctt tgagttttat
    50761 gtgtggaaga tatgtagggt tttgtttggc caaagggtat agaagtggta atgaagttta
    50821 tagaatatgg aatgaaaatc aaatatctcc ttttagatat gtaccaacat ggtcagatac
    50881 actttcaaat tatcataata tggaaaaata tataagcctt atgtgtaaaa agctagaaga
    50941 tttttattat ggttctgcta taaagagtgt tgttgattgg tacatagaat ctcttggaag
    51001 tgctaccatg gaaaacaata taatatctgt acaaattgca cttgaaactt tgtcatatgt
    51061 aattctagtg gaacaaaata agatacttac agatgaagca tttgactgta atttggcatc
    51121 taaaaatata agactcttac ttgatacatg taagatacca tatggtaaac atgaattaaa
    51181 tatatttgat aatataataa aaaataaatt tgatgatgga gtggatttag ttatttattt
    51241 aagaaatagc atagttcatc caagtagaaa gactcataga gctgtgttag aggttgaaga
    51301 tatttggaat ataatttcaa taggaacgag atatattgaa cttgttttac tctttatttt
    51361 aggttataga ggagaatatt caaacagatt agtagaaaga tgttatggtg aagtggaagt
    51421 tgtaccttgg aactagattt ttatatttat tttaaaatat atattgacat atattgcctt
    51481 atgctataaa atcaatatca taataataat tcagaataac attaaatgct aagaaaagaa
    51541 atagtaaaag tagttaatct taaacagaga gtttccgatt ggtgagagga gcaatagatt
    51601 ttactttgaa cacatctttg agcaggactc tgaaagagta gaaatacttt attaggagat
    51661 ttccggaatc cttgcacccg ttatagtgct agagtataat aattttattg tacttaaaga
    51721 ggttagtgcc gtgaggcatt aatgaacaga ggtggaacca cgagagttaa ctcccgtcct
    51781 ctagcagaag ctagaggcgg gagtttttta atataatttt ttaagcgcgc agagaattat
    51841 attgcaatag atacactttt taaaaaataa tcaaaatatt ttaaaaatta aaagacgagg
    51901 gagaatatta tgaaaaatat attaaaaaaa gtaggaatat ttacaattat gttaggttta
    51961 ttaggtggag ttgtaggttg ttcaaaacca gataatgaaa aagataagga tgcttcaaag
    52021 gaatctaaaa aagaagtagt tgtagggttt gataatacgt ttgtaccaat gggattttta
    52081 gatgaaaagg gagatacagt aggctttgac gtagacttag ctaaagaaac atttaaaaga
    52141 cttggaatgg aagttaagtt tcagcctata gattggtcaa tgaaggaaac tgaattaaat
    52201 gattcaaaaa ctgtagatgt attatggaat ggatattcta taacagacga aagaaagaaa
    52261 atagtatcat atacagaacc atatttacaa aataaacaga taatagttac tctaagtgac
    52321 tcaaaaataa attcaaaagc tgatttaaaa gataaagaag ttggaacaca acaaggttca
    52381 acagcacttg atgcagtgga aaaggataaa gattttatga atagcttaaa aggtggagca
    52441 ccagttcttt atgatactta tgataaagca cttagagatt tagagatagg tagaactagt
    52501 gcagttgttg gtgatgaagt tttaattaga tactatatgg gacaaaaggg tgaagacaaa
    52561 tacaaggtat taaaagacga ttttggatta gaagattatg ttgtagcaac ttctaaagaa
    52621 aatccagaac tttgtgagaa aataaatgaa acattaaaag aaatgaaaaa agatggaact
    52681 tttgacaaga tttatgataa gtggtttaaa tagaagataa gttagctgtt aagaaggggg
    52741 cactaaaggc atgttacaag gtttagagat agttatagca atgttttgta taacattgat
    52801 agtatcaatt ccattgggga ttggagttgc atttttaaga ttatcaaaga ataaattagt
    52861 aagtggtatt acacaatgtt atatattgat aatgagaggt acacctttac ttttgcaaat
    52921 gatagtcata ttttacggat tacctctttt aggaattgta tttgacagat ttacagctgg
    52981 agtagtagct ttcttcttaa attatgcagc atattttgca gaaatattta gaggtggaat
    53041 acagtcaatc gatagaggac aatatgaagc ttcaaaagta ctaggatttg ataagtttac
    53101 tatgtataag agagtaatct ttccacaagt ttttaaaaga atactagcac ctatttcaaa
    53161 tgaagtaatc acattagtaa aagatacatc tttagtatat atattaggat taaatgatat
    53221 tttaagaata tctcaaatag caatgaacag ggaagcaagt ctgttaccat tatttgaggc
    53281 aggagcgata tatcttatat ttgtagctat acttactaag ggatttgaat tacttgaaaa
    53341 aaaatattct tattatagat aaagttacaa tattatagga ggaggttttt tatatgttga
    53401 aaatcaaaaa cttaaataaa tcatttaaaa aaaatagagt acttaaagat atttcttttg
    53461 agttagaaga aggtcagatt ggagttttac ttggtaagtc tggtgcagga aagaccacaa
    53521 tattaaggtg tataaatggt cttgaagaat ttgatagtgg agagattata atagataatg
    53581 aggtaataaa aaataagaga gatatggcaa aaatacgagg aaaaataggt atggtttttc
    53641 aaaatttcaa cttatttcct catatgacag tccttgaaaa tataattgaa tccccagtta
    53701 atgtttttaa agttcctaga aaagaggctg aagagagggc tagagaactt ttaagattag
    53761 ttgatttaga agataaatta aattcttatc catttgaatt gtcaggagga cagcaacaga
    53821 gagttgctat agctaggtca tgtgcattga tgccaaaagt cctttgtttt gatgaaccta
    53881 cttctgcact tgatattgat actattcaaa gagtagtcaa tataatgaac agacttaaag
    53941 acaaaggtat gacaatatta ataattacac atgatgttgt cttctcaaat aatgttgcag
    54001 ataaaattat aagtataaaa gatggtatag tagaaaatgt tcaaataaaa gaaaaaattg
    54061 tttagagttt tataaatata aactagggta gaattttata atataaataa agggcaagta
    54121 aaatcaaata tactatgccc ttttgttatc tcaaaattta atcttatatt ttatgtttaa
    54181 gttacattat aatttataat aaaaataaaa ggactattta aatatataat gtgaataaat
    54241 gtttaataat ttgaaatatg ataatttttt atgttgaaag cttataatga ttatgatata
    54301 aattggttat agtatacaat ttatgggtat aacaataaaa aattagaaag gaatttttat
    54361 aaaatgatta aattatatgg atatacaaaa tgctctactg ttaaaaaagc taaaaattgg
    54421 cttaaggaaa ataatttaga atttgaagat atagatatgg ttcaaaaccc tcctagtaaa
    54481 gaggagttaa aatcaattta taagactagt ggatatgata taaagaaatt ttttaataca
    54541 agtggtatga aatatagaga attgggtctt aaagatattg taaaaactga atctgatgat
    54601 aaacttttag aaatattggt aagtgatggt atgcttatta aaagaccatt acttttggat
    54661 ggtaaaaatg tattattggg ctttaaagaa gatgtatgga aaagtacttt gctaaaagaa
    54721 gattaggaag agataggtgt gttgattaaa attattaatt aatacaccta taaatttatg
    54781 tattaaatct aatttttata aatattaatt agcaaattca aatcaaaaaa attcatatca
    54841 acaaacatat tacttcttat tacaaattat atcatatgtt ttatattaaa atattataat
    54901 attacaacga attgttacaa aattacttat tattaaccat gaacatttgt tttgtgctat
    54961 catatttata taagggaatt gtcataaaaa atatcttgtt catacagttt tatatagaaa
    55021 aaagaaatga atcttttctt tatataagta tattttgtaa attgcctcta tatttatagt
    55081 ttaaataata gtggtattaa aaatctgaca acaaaaataa aactttcaaa aaattaaatc
    55141 taaaaagaat aggagataaa tatgagtatt gaagatttat atgattttga atgtgttcct
    55201 ttgaacaatg agattgatat tgatgtttta tttgaaaaga tgatagaaga tggaaaagaa
    55261 aaagaatata caccaattat agtcattgat gaaaaagtag ggctattaag aaaaaatata
    55321 gatatgatta ctaaagagta tggttctctt gaaaactata gagagtattg tttaacaaaa
    55381 tataatgaaa ttgatgtaaa tcaatttttt gattttagga agagtgagat ttcagaatta
    55441 ttaaaggagc taattgattt agaagatgat ttttatgatt ataaacattt tagaccaatt
    55501 atgaatatag atatatttca tgaatataac aaagtttaca tagctaaaat tccaacaatt
    55561 aaaccatatg aagtatttgc atacatacct attggcggat ttaatgattg tcctagagat
    55621 gaagaacata tagctattgc aaaatattgg tatgaaaagc atggaatctt tccaatcgca
    55681 attggatgtg atacagttca atattctgta aaaaatttaa ctaaagatgg taaaaaattt
    55741 gatgaattat gtattgaatt agtattttat tgtgaggata ttattataca agggtatgaa
    55801 accttaaagg ctcttaagga tgtattaaaa cgctctacaa tagtgctttt ttggtgggat
    55861 tgatattcca tcatttagat agtattaaat tgttagtcac caagaatcca cttgctttag
    55921 ttatggggag tgtgtcaaac taggttttta tacacagtgt agcatagtaa tatgtttaaa
    55981 ttacaaaggt taaaaaaata ctttaatatt tttaatatta taattaatag atttaaaggt
    56041 aattataatt tataaaataa atactttata tgttataatc attaagaatg taaaaaaata
    56101 atatatagtt ttatagttca tatttttcca gatatggagg taaattttgt gaaggaaaaa
    56161 gaaaaattag ataaattaaa aaaaatgtta cttgaattag gcagtgttgt agttgcttat
    56221 tctggtggag tagatagtaa ttttttgctt aaggtcgcaa aagatacatt aggtgaaaat
    56281 gttatagctg tgactattca tgcaatgatg cattcaagta gggaaattga agaggctaaa
    56341 caatatactc aaaattttgg tgttaaacat atcatattaa atatagaaaa ctttgattta
    56401 aaagaattta aagaaaatgg tgttgataga tgttatcatt gtaaaaaata tatattctct
    56461 aaaataaaag aggtagcaaa agaacataat ataaagtaca tagtagatgg aacaaatata
    56521 gatgatttag gagactatag acctgggctt aaggcattga gtgaattagg agtaattagt
    56581 ccattaaaag atagtagttt aaaaaaagaa gaaattaggt cgctttcaaa aacattagga
    56641 ttaaatactt ttaataaacc atcatttgca tgtcttgcga gtaggatacc ttatggagtt
    56701 gaaataacag atgaaaattt aagaatagta gaaaagagtg aagaatatct atccaattta
    56761 ggtttttctc aatttagagt gagaatgcat ggagatatag ctagaataga agttggacag
    56821 gaagaactag gtaaattttt tgaaaataac aattttaata aagttgatac taaattaaaa
    56881 atatttggct ttaaatatgt tacactagat atgtcaggat ataaaatggg aagtatgaat
    56941 ttaaatgtgt agattatttt aaaaataaat aagttttata gttaatataa ggaaacagga
    57001 ggttttatga aaaattatac gttaatatcg ccatgttttt ttggaatgga aaaaatgctg
    57061 gctagagaga ttactaattt aggatatgaa ataataaaaa cagaagatgg aagaataaca
    57121 tataaaactg atgagtttgg aatagcaaag tcaaacatgt ggttgagatg tgctgaaaga
    57181 gtacatctta aaattgctga atttgaggca aaaagctttg atgaattatt tgaaaataca
    57241 aaaagaataa actggtctag atatatacct tatggagctc aatttcctat atcaaaagct
    57301 tcctctataa aatcaaaatt atacagtaca ccagatgtac aagccatagt aaaaaaggct
    57361 atagtagaaa gcttaaagaa aagttatttg gaggatggtt tgcttaaaga agataaggag
    57421 aaatacccta tttttgtatt tatacacaaa gataaagtaa ccatttctat agatacaaca
    57481 ggagatgctt tgcataagag aggatataga gaaaaggcaa ataaagctcc aataagagag
    57541 actttagctg ctgggcttat ttatttaact ccctggaaag caggtagagt tttagtagac
    57601 cctatgtgtg gttctggtac tatattgatt gaagctgcta tgattggtat aaatatggca
    57661 cctggcttaa atagagagtt tatatcagaa aagtggagaa ctcttgataa gaaaatatgg
    57721 tgggatgtaa gaaaagatgc ttttaataag atagataatg aatctaaatt taagatttat
    57781 ggatatgata tagatgaaga atctatagat atagctagag aaaatgctga aatagcaggt
    57841 gtagatgaat atatagagtt taatgtagga gatgcaactc aatttaaaag tgaagatgag
    57901 tttggattta taatcactaa tcctccttat ggagaaagat tagaagataa agacagtgtt
    57961 aaacagttgt ataaggagct tggttatgca tttagaaaat taaaaaattg gtcgtattat
    58021 ttgataactt cttatgaaga ctttgaatat gagtttgggc aaaaagcaga taaaaaaaga
    58081 aaattgtata atggtatgtt aaaaactaac tttttccaat atccgggtcc taagcctcct
    58141 agaaataata aataagtttt acatgattta tttgtaaaat ataaaatttt attaaaataa
    58201 gtaaaacatt atgatgcctt gaaacgtcta attattgtga ggagattttt gtgaacaaat
    58261 ttaaagattt ataggattag gaggagttaa atgaaagtgt taaagcttat tactgtagta
    58321 gccctgatga tgttatttgt tactggatgt aatataaaaa ctgaatctcc agaacaatta
    58381 gcgaagatac ctgactatga tgatacaaaa aaagtattgt atgatggtat tgaccagtta
    58441 ctaaaaccag attcatctat gatattgcct tctaatacaa aagaagtagg aaaaataaat
    58501 aaggtagatt taaacagcga tggaattgat gaattagtag tatttgaaca aaaagaagat
    58561 ttaagtaata atgtgagtca ggtagggttt gtaaccttga gttacaatgg agaaaaatac
    58621 gtacttggag accatttttt agaaaatggc gaatcaatag aatatgctaa tttttatgat
    58681 ttggactcag atggatataa ggaagttatc ttattggtta aatccaaaga caaaacgaat
    58741 atgcatatat ataaagtagt agataatgaa ataacaaaaa tatatgactt ggatgcatca
    58801 tggcttcaaa ataaagaaga ttttaatgat atgaaagtaa aaattggata tatagatgga
    58861 gatgacaagt tagacatatt gatgcttcat ttgaataata agactaatga aatgtttgca
    58921 agtgttgcaa attttgatgg gaaaatgaaa atcaaagatt ctgttaagtt tgaaaatgta
    58981 aaaaacttaa gtgaattata tataacatta ggtaatgttg cttcatctgt tggaaattct
    59041 tctgcagcta taaaaggtat tgtacttgat attcctatat tgaaagataa taactatatt
    59101 acgcagatac tttatatgaa agatgggaaa attaacaaag cttttagtga ttatgataaa
    59161 actattacta aatcttatta tatacctgta gatgatattg acaaagataa gattatagaa
    59221 atacctatag ttgcaggcag tacaggtaat aataaaaata cttatagttc taaatcatct
    59281 gcaactataa gttggtatag atggaatgga aaagaaggtg ctgactcaag tttaatattt
    59341 acaagtcaga tatattataa ttataaatat aattttaaat tatttattcc aaataattta
    59401 tttgataaaa tacttgttga acaggaattt gttggagaaa aagcagtatt taaattttac
    59461 tattttgact attcagaccg taagaattta tttaatatag tagtagagag taaaaataaa
    59521 cttgaagata gaaaaaatac aggtactcaa aattctattg tacttcaaga gagcgatgaa
    59581 tatactttct tactagttgt aaacaatgca aatgaaatgg ataagctaga tatgactata
    59641 gacgcattaa aagaatattt ctcattaata tatggttaat attatactca attggaggtt
    59701 ttattttatg aaggaaaaga tacttatact agaagatgaa attggtatta gaagttttgt
    59761 tagtataaac ttaaaaaggg aaggctatga aatagttgag gcaggtactg gaagagaagc
    59821 tatagaaaaa atgacaacag aaaaggatat tacaatagct cttttagatg taatgcttcc
    59881 agatataagt ggtatagaag tatgtaaatt tataagggag aattttgacc aagtaggtat
    59941 aataatgctt actgctaaag ctcaagaaga tgataaaata gaaggattta tctcaggagc
    60001 agatgattac atcataaaac catttagtat aaaagagctt ttagtcagag tttctgctct
    60061 tcttagaaga gtagcaaagg atgattcaag tgttaagtcg agtgagatag tttctccacc
    60121 atttatactt gatatagaca aaagaaaatt atttaaaaat ggaaaggaaa ttgagcttac
    60181 accaactgaa ttttcaatag tgaaatatct aatatcaaat gctaagcagt cgttaagtag
    60241 agaccagata ttagacgaag tatggggaac taactattta tatgatttta aaatagtaga
    60301 tgtaaatata agaaggataa gaaataaaat agaagatgac ccatcaaaac caaaatatat
    60361 acaaactatt tggggttatg gatactgttt tagaaaggaa gaataatagt gttacatttt
    60421 gaaggtctga gaaaaaaagt aataaaaaac tattttataa taattattat aatggttact
    60481 ctgtttgaag gattgttcat gttttacata caaaactact attatgattc tgtcaaacag
    60541 ctacttgaat ctgaaataaa atatgctgat gaatataatg ctattacaat ggaaactaca
    60601 agttttgaga aaaaagtaaa aaatatattt gataaacaac ccttaactaa aaattcagaa
    60661 tttggaattt caataataga taaagataaa aatattatat tagaccaata tggttttaaa
    60721 agtaaagaaa aagcaaacta tgaagatgtt aacaatgcat taaaagatat aaaaactaaa
    60781 aatttaacac cttatactta tagaatacca gatacagggg agcatgttat gagtatctcc
    60841 ttaccactta aggtaaataa tataatagaa ggtgttgtta gatatacagt atcattagat
    60901 gctattgata atgcaatatt aaagcaagct acatggctta tattagcagg aatatttata
    60961 cttattatag ctatactaat aagtcttaaa tttgctgaga ctcttataaa accattacga
    61021 gagctaaaga aatttgcaaa tgaattggct gtaggaaatt ataatataaa attagaaaag
    61081 atgaagattg tagatgatga aattggtgat ttagcacaga catttgaaca catggcacat
    61141 gagattgaca aaagtgaaaa attaaaagag gaatttatat catctgtatc tcatgaacta
    61201 aggactcctc ttacatctat aaaggggtgg agtgaaacct taggttatga aagtataaca
    61261 agagaagaac tagacttagg tttaggcatt atacaagatg aaacagaaag acttataaaa
    61321 ctagttgaag aattattaga cttttcaagg ctttcttcag acaggataaa acttcatgtt
    61381 gatatagttg atgttgaagg tttaattgta ggtgttgtaa atcaacttaa agttaaagca
    61441 gctgaaaaag atatatcact tttatttgaa tttgaaaatg aatttataga gaacattcaa
    61501 ggagataaaa atagattaag acaggttctc ataaatttaa tacaaaattc atttaaattt
    61561 acgagtcaag gtggttacat aaaagttgta gcttctcaag atgaagagat aacaaccata
    61621 tcagtagagg ataatggttc aggtatagaa aagcaaaatt taaataaagt gttagataaa
    61681 tttttccaag aagattataa taaggctggt agtggattag gactagcaat tagtaatgaa
    61741 attgtaaaac ttcatggtgg aagaatgaaa atagaaagtg aaaagaatgt tggaacaaaa
    61801 ataactttta atataaaaaa taaatttgct aaacaagcat aaattcttag aaagaggatt
    61861 aagatgagaa acataaaaat gatagtagca tacgatggtt caagatataa aggatatcaa
    61921 aaattaggtg acaataatat gactattcaa gaaaaacttg aaaatgtttt aagtaaaatg
    61981 actaatgaaa cagtggagat aataggttct ggaagaactg atatgggagc tcatgcaaga
    62041 ggacaagtgg taaattttag aactaattgt atggattctt tggataaaat tcaaaaatat
    62101 ttatatgaat atttaccaga agatatagtt gtaaaaactg ttgaagaagt tgatgaaaga
    62161 tttcattcaa gatacaatgt aaaatcaaaa acttatatgt ataaaattga caataataag
    62221 tatcatagtc cttttataag aaaatatgct actcatgtaa gtaaaaaatt agatttagat
    62281 agaatgagaa aagcaagtga gtatttagta ggagaacatg attttaccag ttttgcttct
    62341 tctaaatcta agaaaaaatc aaatgtaaga gaaatttatt ctataaatat aaaagaagat
    62401 gataatgtta tagaaatata tgtagaagga aatggatttt tgtataacat ggtaaggata
    62461 atagtaggtg ctttaataga tgttggtcta aaaagaagag ctccacaaga tattaagtat
    62521 atgcttgaat caaaagatag atgtcaatca tcagatactg caccagctaa aggactatgt
    62581 ctttggaaag taacatatta atcaattata taaaactctc tttaaaataa aaataaaata
    62641 aattatatag ttgacataaa tggaaaaata aactattata tattttataa gagagatata
    62701 aaactttata tttaaatcct gtgagaaaga gagtaacttc tatgtgtttt atagagagct
    62761 gaggatggtg gaagcttggc aaataagtat tagtgaaaag aactttggag gatactaatt
    62821 gaatttagta tgttagtagg taatctcgcc ttaagagaaa gagtggataa gtttatctta
    62881 tcaattagag tggtaacgcg gatatatttc gtctcttggt ttttccaaga ggcgtttttt
    62941 aatatattta attattagtg tttatctggt atgttgaaca tttactaatt gattagctaa
    63001 gtttatcaat aagagtggta ccgcggatat ttcgcctctt agtattttaa aatactaagg
    63061 ggttttttta gtattaaaat gattttatgt gagtctaaat tctcagagtc attcaatatt
    63121 aagaatttct ataaaataaa aattataatt taagattggg aggaattaaa aatgaaggaa
    63181 aaagtagtat tagcatattc aggaggactt gacacatcaa tcataatacc ttggttaaag
    63241 gaaaattatg aagatataga tgttatagct gtttgtggaa atgtaggtca ggaagataaa
    63301 atggaagatg tatatgaaaa agctttacaa agtggagcat caaaggcata tgtggatgat
    63361 ataagtgaag aatttgtaac tgaaactata tttaaagccg taaaagcaga ggctaaatat
    63421 gaaggaaaat acttattagg aacttcttta gcaagaccta taatagctaa aaaattagtt
    63481 gaagttgctc ataaagaagg tgcaaaatat atatgccatg gatgtacagg aaaaggtaat
    63541 gaccaagtta gatttgaagc tacaattgca gctcttgacc cgactataaa agttattgca
    63601 ccttggagaa tttgggatat aaaatcaaga gaagatgcta tagactatgc tgaaaaacat
    63661 aatataaagg taacagcaac taaagctaaa atatattcag tagatgctaa cctttggcat
    63721 gtttcaacag aaggtggaga tatagagcac ctagaaaatg aacataaaaa agatgtttat
    63781 aaacaatgtg tagacccaga agatgcatgt gatgtagctg aatatgtaga agtttacttt
    63841 gaaaaaggtg tacctaaaaa ggtaaatggt gaagaattat ctccagttgc actgattcat
    63901 aagttaaatg agttgggttg taaacatgga attggtgtta tagatatagt tgagaataga
    63961 cttgttggta tgaaatcaag aggtatatat gagactccag gaggaacaat cctttatgaa
    64021 gcacataata ttttagaaag tgctacttta gacaaagata cattacattt caaacaaatg
    64081 gtatcttata aatacggaga acttatttac aatggactat ggtattgtaa attaagagaa
    64141 tctatagatg catttatgga acaaactcaa gataatgtta caggaacagt aaaagttaaa
    64201 ctttacaaag gaaatataaa acctgctgga atatttactg aaaatgctct ttatgatgaa
    64261 ggaatatctt cttttggaaa tagtgaactt tatgaccaca aagatgcaga aggatttatt
    64321 aatttattca ctttaccatt aaaaatcaga gctatgaaag ctggaaaata ataaaataaa
    64381 ttatttaaga gtgtataaaa actattttta ggtttttata tgctcttttt ttatttgaat
    64441 ttattaactt atacagtaaa tagtataaaa aaatatatta tagttccaaa tggcttaata
    64501 atgtgaaaat ataagaccta aaatataaat tttataaata caatagttat tgactctctc
    64561 attgtaagag ggtttatact gaatctaatg aaaatttata gtgaggagat agattatatg
    64621 agaaaaataa ttgaaattaa acatcattca catgattatg agtgtatgtg gaatggtata
    64681 gaagatttat atataaataa aaccggtgaa tgccttccaa acgatttttt ctttttactg
    64741 tcaggttttg gttcattttg ttatatgaaa acaaataaag ctgatttgaa aagaatggta
    64801 gctttgggag atggaaggac aaaacagatg tataaatttt tagcaccaat tgttggattt
    64861 gaatacaaac atcatgagtt taaaaagtat gagcaagcat taaagaaagc aaaatctgaa
    64921 attgatgatg gatatccagt tattttagga gctttagata tgtattatct accatattat
    64981 aagaagctat atcataaaga acatattcct tttcattata tattaatggt aggatatgat
    65041 gatgaaggaa tatatctgta tgattgtggt agaacagaat tattacatct ttcttatgat
    65101 aaattacgtg aaagcatgaa ttgcaattcc cctggattaa gcaaagaaaa tactatttgc
    65161 acaataagaa tgaatacttc aaagaataaa tataacattg ctagagaagc tattgctata
    65221 aagcgtgata tgtttttaaa tccacctaaa ggatttttgg gatataaagg ttttgaaaag
    65281 tttattaaag agttgccaca gtggaacact gaattggata aagatgatta tgataagatt
    65341 ttgaccaata tggttatgtt ttttggaaca gtaccaacaa ttccaaatgc aatcaaagga
    65401 attaaagaac cagatactgt tcaatttaaa ggtggatttg ataaaatgag tagaatgctc
    65461 aacagtattg gggaggaata caaaaacgac tcttttatac aagtagctga tatttttgat
    65521 aaaactgcta ttataattga gaaaatatcc aatattataa tagattactt aactcaaaca
    65581 tgtgatgata caggacaact tccgttattg ttctctgagg tcttagagca tatgaaaaca
    65641 ggatatttaa tcttggatgt ataaaaaata tattgttgac cctaacatta cgtaatagtg
    65701 taatatgaaa atatagcttg aatatattag taggtattga tggctgtaaa attaaaattt
    65761 gaggtgtgga tatgagaaca gtgaaacaag tttctgattt aactggaata agtgtgaggg
    65821 cattacatta ttatgatgaa ataggtcttt taaaaccaaa taaaattaca gatgcaggat
    65881 atagacttta tgatgatgaa tctattaaaa ctcttcaaca aattttattt tttaaggaga
    65941 ttgatattcc tttaagagag gttaaggaaa taatgtcaag ccaatatttt gataaggttg
    66001 aagctctaaa aaatcaaaaa aaattactta ttttaaaacg aaagagactg gatgaattga
    66061 tagagcttat aaatcaaact ctaagaggag aaggaaatat tgattttaaa gagtttgata
    66121 tgagcgagta ttttgatgtt ttagaagaat ttaaaagaga gcataggaat aaggtaatta
    66181 aaatttatgg tagtgtagaa aaatacaatg aatatataga aagagttaag tctaatgaag
    66241 agaaaattgc taaaatggct ataaaacaat atggaactat tgagaagttt gctaaagcta
    66301 taaaaacaaa ttttagcagt gatatattga atttaggaga aaaatttgat agatataaaa
    66361 atgattgttt aaaagaaaaa catccaaaat taaaagaatt atatagaaag cttgtagaag
    66421 atttaaatag gaatccttct tcaacagacc ttcaagaaat agcaaaagag ataacagata
    66481 tatctaaaaa agattatgaa attttctcta tggatactgg tgatgacaac tggtattata
    66541 tggttcaaaa ttatctagta aatcctatgt ggatagaaga agtagataaa aagtatggaa
    66601 gtggagcagg taagtttatt ggacaagtac taaagactta tctaagagat agaaaaccaa
    66661 agataaatac attgtatgaa aaacttgtag aagatttgag tagagattgt tcttcaaggg
    66721 aagttcaaag cattgttgaa gaaatagaca atgaaatgaa aagaagtaat gaattttata
    66781 aaatagacaa tggtgaaaga tactttgatt atatgtcaga gctttattta caagattcta
    66841 actatataaa agtaactgat aagaattatg gtgatggtgc atctaagttt attggagaag
    66901 cttttaagat ttattttgat aataataatt gttgaaaatt tggaagtaaa aaatatgcaa
    66961 gttttataaa agcacaaaaa taaggatgta gattagctcc atctatatcc ttatttaaag
    67021 ttattaaaat atatagttta catcaaactt aacactttca ataatatttc ccaaatatgt
    67081 ttttatactt tcaacttctt ctaaagattt taatttattt tcagtataaa ttgctttgtc
    67141 cagaatatta aaccttaatc ctatttcatc aaagtactca tgatttaaaa ctttgtacca
    67201 atggtttttt tctttattcc aactcgtaga tattgaatca gcttcttttt gagctttttc
    67261 ccaatcttca ttttctatag atttttctaa aacagatata ttgtctttat atccttctgt
    67321 aaaatcatat agtttattgt taacataaaa tccaaataat acaaataaga tagtccatag
    67381 tataacaaat gttgtagatt tcaatattaa tcaccctttt tattttgaat aaatattttg
    67441 tcattttcat ctaaaacaca aataagaaca tctttaaaag tttctatgtg attagatttt
    67501 aaaataccca ttaaccagtt agtatctttt tgagctatgt ctagattttt atttattatt
    67561 ctaccatcca gtataagtgg gataggtaaa tgattaaaag ctcttggagg agtactattg
    67621 tagcttgatg ctggtacaac acttagatta ccatcagtct ccaaaatagc atattgtaca
    67681 tcttttaggt taaagtatcc ttgaatccta agttgttcta ataattcatc tatactaatt
    67741 ctttcttttt taagctcttt atatacaatt tttcctttat ctattaatac agaaggttta
    67801 cctgataaaa atgaacttaa ttttctactt tttaatgata agaatgaaat tagagtctgc
    67861 atgattacaa gtccagatat tgctgcaaca ccatttatga ttggtatatt attattttcc
    67921 attgggacag atgcaacttc tgcaattaat agtgttataa ctaaatcaaa acagttcatt
    67981 tcagctattt caccttttcc catgactcta agtgcaatta gcactgttat gtataatata
    68041 atacttctta ttaatactac tgtcatatct atcaattact cctttaaaaa atatttacac
    68101 ttagttagta tatcctatat aaaaaattta attcaaagta taaaaaacct taaataattg
    68161 gattcaacta tttaaggttt ttttgataat tttaatatta aattttttat ggattttctg
    68221 ttacttttat ttattttaat aacagattca acaaaactct ttttatctcc taattttaag
    68281 ataaaatcag gatattcttc aaattcattg agttttatta atttgaaaga agaagataga
    68341 tttttaaagt taataatttt agagttattc actaatacac ttcttttttt aaaataaatt
    68401 tcttttttac ttatatttag tatagttaat atttgtttaa gatatattat tatatcttct
    68461 ggagttctat caaatttgag ttcaaaattt tcatcttcaa agtagggaat ataatataaa
    68521 ggtgttttga gagcaggtaa tttattatat aattcttcaa gaatatcgat atttttaggg
    68581 gagttaaaga aaaagcattt acatacattc attaaatcca cagcatctga aagtgagtta
    68641 tgtttaatat ctccttctac agaaaaaatt tttttcatat tcagtaaaga tatttgctta
    68701 gataagattc tattattgta tgtaatatgt tgagatataa aaggttgaat gtcaatcatc
    68761 atattaaata actctaagca tttacctgta tatttatata ctctaaatga agttagaagg
    68821 ccagttatat caaaatcacc ccaattatat attgtaacat catcaaattt acaaaaccat
    68881 ttataaaaat catccataac atataaaaga ttaggagcat tattgatatc tagttggttc
    68941 aatttggtta aatttttaca tttatttgaa agtattttat tgtattttgg cttaactaaa
    69001 gagtaataat tatctattgt attaaattcg ttatcaacta aaactccacc aatagaaatt
    69061 aattccgcac cattatattc ttttggttta tttttattat catctagtat attaaattca
    69121 aagtctataa ataacttgta tttcataaat ctaaagcaca tcctcaggta aattatttat
    69181 tgagcctaag catcataaga atcaatagat ataatgactc taaacatcaa aggttcatta
    69241 caacttttat ttatttcata atttaattca aataaatctt ttaagatata atttataagt
    69301 attctttccc aacccatttt taaattaact ttagagtcta ttaatatatt ttctatcttt
    69361 ttaaatattt ctatatttgc tggtattata ctgagctcaa tattactttt aaacgggtta
    69421 gactgtaaat ctgttataag tatatttttt aattcctctg taagttcaga aattaaacta
    69481 tcacctatgt atttttttat gatttcctct ctaatttctt ttaaatttag caatattagt
    69541 acctgctact tacatagtag cttttccttt ccttttaata ctattattca tttttgaatc
    69601 ttatttagat atattttaag attaaaagtc tttagctata taatttttta cccattttta
    69661 acttatatta acatattaca ggcttatatc tccaccctgt ttacattgag gatggagtat
    69721 attgcctatt ttgataaaaa tgataggttg ctatttgcct attccttttt ctgataattt
    69781 ttctaacata tctttggtca ttttatctaa atcataacta aacttaaagt tccattcttt
    69841 tactgcacta ctactgtcta gagagttagg ccaagaatca gctatacttt gtcttacagg
    69901 gtctacatca tattctatca caaaatcagg aatatatttt tttatagaat cagctatttc
    69961 ctcaggagaa aagctcatag cagtaatatt aaaagcattt ctatggatga gtttatcagc
    70021 tggagcttcg attaaatcca ctattgattg aagtgcatca ggcatataca tcatatccat
    70081 ttttgtacct tctgctatgt aagatttata tctcttattt tttaatgcct cataatatat
    70141 atcaactgca taatctgtag ttcctccacc aggaggcgta acataagaaa taagacctgg
    70201 aaatctaaca cctctagtgt ctactccaaa ttttgagtga taataatcac atagtaattc
    70261 tccagaaact ttagtcacac catacatagt attaggtctt tgtaatgtat cttgaggagt
    70321 catatttttt ggagaatttt caccaaaagc agcaattgaa ctaggtgtaa aaaatttaca
    70381 atccaattct ttggctattt caagaccatt tattaatcca ttcatattta agttccaagc
    70441 ttctagaggt ttactttcag caactgcaga aagtaaagat gctagatgaa ttatagtatc
    70501 tacatcatat ttttttgcaa tttcaaaaaa acgattctta tctgtaacat ctaatatctc
    70561 aaatatacca gattcacata ctggattacc ttcttttact ctccttgaac tagcgattac
    70621 attttgttct ccatactcat ttctaagctt tattgttaat tctgaaccta tttgtcctaa
    70681 tgcacctgtt ataagtattt ttttcaattt tacaacctcc taagggttta atttatgtag
    70741 tactacttat ttttatttta gcaaatcttt tgtttaaata caaagaatta aagataataa
    70801 tatacgactt aattgaatga agtgcagtaa gtgcctaaaa atttaaagct aatatataat
    70861 ggtatattgt ataacaataa aagagtagat taaattatta tatatagatt gtgtgactaa
    70921 gtcacagaaa atagagttaa tttaatatat aataaaagca tatcaagtaa agctttaaat
    70981 taaagtaact ttataaataa aaagtaatat aaattgataa aattataaat ttatttatag
    71041 tgaatatggg ttggatttta tagatacaaa aatagtatat atgatatgta gaccattagc
    71101 aggtttaaag tagcaaaaca tataaaataa aatttgaaag gaagtataaa aatgacaaga
    71161 ccatcaatat atcatagcca aggatacact tgtgcagagg cattaataaa gtcttataat
    71221 gaggaacata acacagatat accaatctca ataggaagtg gtatgggggt tggaatgaat
    71281 gttggaagtg tttgtggagc tgtaaatgct gctgttgtta taatagggta tttaaatggg
    71341 cgaaatagta atttagatga aaatatagca aggaagtatt caagagagct attgaataga
    71401 gtaagaaata aatacagctc agaaatatgt gtatctctta aaaaaaataa agtaacttgt
    71461 gaagaaataa taaatttcac atatgatgct ctaaatgata tgctaaaaaa tcaaaaataa
    71521 ttctaagaaa caagtatttt acattcgata gaatactt
//
LOCUS       DAYAOO010000008        68782 bp    DNA     linear   BCT 12-OCT-2024
DEFINITION  TPA_asm: Clostridioides difficile isolate ST8-SSI-h139-18
            SAMN40601845-rid21577343.denovo.008, whole genome shotgun sequence.
ACCESSION   DAYAOO010000008 DAYAOO010000000
VERSION     DAYAOO010000008.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN40601845
            Sequence Read Archive: SRR28438827
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 68782)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 68782)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-MAY-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-MAY-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002157583.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002157583.1
            Genome Coverage       :: 163x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/11/2024 16:19:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 4,038
            CDSs (total)                      :: 3,963
            Genes (coding)                    :: 3,930
            CDSs (with protein)               :: 3,930
            Genes (RNA)                       :: 75
            rRNAs                             :: 6, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 60
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 33
            CDSs (without protein)            :: 33
            Pseudo Genes (ambiguous residues) :: 0 of 33
            Pseudo Genes (frameshifted)       :: 7 of 33
            Pseudo Genes (incomplete)         :: 25 of 33
            Pseudo Genes (internal stop)      :: 11 of 33
            Pseudo Genes (multiple problems)  :: 8 of 33
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..68782
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN40601845-rid21577343.denovo.008"
                     /isolate="ST8-SSI-h139-18"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Denmark"
                     /collection_date="2018"
                     /collected_by="Statens Serum Institute"
     gene            208..1425
                     /gene="ilvA"
                     /locus_tag="ACGI5H_000602"
     CDS             208..1425
                     /gene="ilvA"
                     /locus_tag="ACGI5H_000602"
                     /EC_number="4.3.1.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905953.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004794 - threonine deaminase activity
                     [Evidence IEA];
                     GO_process: GO:0006567 - threonine catabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="threonine ammonia-lyase"
                     /protein_id="HFG9696332.1"
                     /translation="MMNVTLTDVKEARETIKNIVKRTDLLESVKLSEKTGANVFYKCE
                     NLQKTGSFKLRGACNKIASLTDEEKANGVIASSAGNHAQGVALGAKMTGIKSTIVMPA
                     TAPLAKVSATKGYGAEVVLNGAVYDDAYAKAVEIQKETGATFLHPFNDKYVIAGQGTI
                     SLEIFEQLDNKVDTILCPVGGGGIISGVAVAAKALNPNVKIVGVQTANIPSMKESIKN
                     GKVTTAFNDTTIADGIAVKTPGDLTFEIINELVDEIVVVEETEIAESILFMMESQKIV
                     SEGAGAVCTAAILSGKYVPAKDENVVCIISGGNIDINTLYRIIGVALAKEGRRYSFST
                     IMEDKPGNFAELTRIISENGGNILSANQGKLSAGEALGKQSAEFILETIDYDHIARIK
                     KAIEEKGFKIIEL"
     gene            1520..1900
                     /locus_tag="ACGI5H_000603"
     CDS             1520..1900
                     /locus_tag="ACGI5H_000603"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416451.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RidA family protein"
                     /protein_id="HFG9696333.1"
                     /translation="MKHEVIHTNDAPAALGPYSQAIKAGNLLFVSGQVPLVPETMEVV
                     EGDVQAQTAQSLKNLKAILAESGADFSNVVKTTVFIKDMNEFGAINEVYAEYFGENKP
                     ARACVEVARLPKDVKVEIEVIAVL"
     gene            2184..2666
                     /locus_tag="ACGI5H_000604"
     CDS             2184..2666
                     /locus_tag="ACGI5H_000604"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416454.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucose transporter subunit IIA"
                     /protein_id="HFG9696334.1"
                     /translation="MLNFFKKNKSYKLHAVVSGNSINIEKVNDSVFSKKLMGDGVAII
                     PNSNVVVAPCNGKVTVLTESKHAFGMVSDEGVEILVHIGIDTVSLQGEGFKNEVSQGD
                     TVKKGSPIISFEREKINSQGIDCTTIIIVLNHSEFSEINCMVENEVVAGQDTVIEIMK
                     "
     gene            2687..3502
                     /locus_tag="ACGI5H_000605"
     CDS             2687..3502
                     /locus_tag="ACGI5H_000605"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905948.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HFG9696335.1"
                     /translation="MRVVKIFNNNALSTVTNDRKEAILLGLGIGFNKRPGDKVNEDKI
                     EKIYYVQDHMQTKFLELLKNVSPEVMDASQQIISLIPGNEGKFNNKGILSLVEHISFA
                     IDRMKNNVFLPNLMLLDIKMMYSKEFELGVKALEIIYRVCHIHLPEDEAGYIALHFVN
                     LQSNDNLAYDTLKFVKGSIDLIKECYGLELDESSLSTLRFRTHLKFLAQRIFKNEICQ
                     DDKMIEMYDYLINNHPKNKEYLEKLNVYIEKEFRYKLDKPEKIYLLLHLTKIL"
     gene            3553..5103
                     /locus_tag="ACGI5H_000606"
     CDS             3553..5103
                     /locus_tag="ACGI5H_000606"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003431026.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HFG9696336.1"
                     /translation="MKEKLLGGLETFAKAMVQPLMYLSSAGILMVVGVLLTNDMLLGV
                     LPFFKWEPIQIFGSLIYNCIMAIINNLAVIFAIGIPAALAKKEKHKAALIGFMSYIIY
                     LTASNTMLTSLGQLAKESKMLGLIGTGQATILGIQVVDTSVFGGIILGCIAGYVFNRT
                     SNKTFKGALQIYSGANFSFICMFFVSILIGVVSNFIWPLAQQGIASLANVIKDTGTFG
                     LFLYGFLERILVPTGLHHLIYTPFQFSDLGGVLKVGADTVSGAYAIVMTEMNLPVERF
                     SDSIYYMATGFTKMFGYIGIGAAFIYTAYKQNKKKVKATIIPLIITAVLASVTEPLDF
                     MFVFCAPFLFFVHAVIAGLFIALLKIFDVTALCGGNLLVSIIMNTTVGVEKTHWPVMM
                     ILGLAQIIVYFVVFSFLIKKFNYKTPGREDESTATGEEQSKQLNLDAGIENIIDGLGG
                     KENINTVENCITRLRVNVKDESKINEDIINLTPNSGIVRKGKDIQIIFGLHVHEVRRA
                     VEDFLEAY"
     gene            5200..6552
                     /locus_tag="ACGI5H_000607"
     CDS             5200..6552
                     /locus_tag="ACGI5H_000607"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003431025.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phospho-alpha-glucosidase"
                     /protein_id="HFG9696337.1"
                     /translation="MIITIVGGGSTFTPGIVKSIALREKELELEEIRLFDIDKERQDK
                     VAVVVNWILKEDVKTDVKLTVTNCEKEAYTDATFIFAQMRVGKYEMREQDEKIPLKYG
                     CVGQETCGCGGMAYGLRTIQPMIKVIDDVEKYAKKDYWILNYSNPAAIVSEACRKLRP
                     NARIINICDMPIAIIDMIAGSLNINDVHNIRYDYFGLNHFGWFTSIDYKHRDLMEEIK
                     EYIKENKILLPKSYIENLNKSRSTGNRHAVSSWIHVWESVYTMLESFPKYLPNTYLTY
                     YLLSKETVEHSNINRTRANEVMESREKDLFEGVRHYLETGEISEKAFYAGSHGDWISD
                     LAVSIKNDTRSRFLVITENRGAIPNMPYDAMVEIPAYIGKDGPEVIARGPIPLFQQGL
                     MMQQLNSEKLIVEAYIENSYEKALQAFTLNKTIPSMNVAKEILDEMIEVNKEYWPELR
                     "
     gene            6683..7441
                     /locus_tag="ACGI5H_000608"
     CDS             6683..7441
                     /locus_tag="ACGI5H_000608"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897697.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_function: GO:0043565 - sequence-specific DNA binding
                     [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HFG9696338.1"
                     /translation="MNIINKIFWEEDRIGMITNNLEADTHSHCMLQLFLGIEDSIEIT
                     VNEKLVKCNCIIVDKNISHSFSARKKVYYSAIIEPTSIYAEQLTSKMNDFGYWICDND
                     GLEKLRQQGTFLIDNSSKEQYLRFMEMLNNYLNIPITLKHYDDRITELLNLLRTCNCD
                     NHTISSFADKVSLSASRLSHLFKEQIGIPLKSYILFHQMECAFRELLSGKNVTEASMT
                     AGFDTPSHFAGTVKRMMGMPVSLSLKDSEFLKVY"
     gene            7488..8207
                     /locus_tag="ACGI5H_000609"
     CDS             7488..8207
                     /locus_tag="ACGI5H_000609"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transglutaminase family protein"
                     /protein_id="HFG9696339.1"
                     /translation="MNKEYLEETKMLNYNEPQLKLLVSSKNWLELDDFHKIKSIYEFV
                     QNDILFGYNASDMLSATQVLNDGMGQCNTKATLLMALLRAVNIPCRLHAFDVTKDFQR
                     GATSKLISLLAPKYILHTWVEVFYQDRWIALEGVITDKKYLEAIQKKFFNHGGTFKKY
                     AIATNDLKNTSIDWDGKDTFIQKEAIVYDYGIFPSPDVFFSTHSQHMSKLKNFIYVHL
                     IRKIMTKNVCKARNNYIDKNE"
     gene            complement(8331..9731)
                     /locus_tag="ACGI5H_000610"
     CDS             complement(8331..9731)
                     /locus_tag="ACGI5H_000610"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416474.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MDR family MFS transporter"
                     /protein_id="HFG9696340.1"
                     /translation="METQSNNKKGNLIIAIVMTGAFISSLSQTLLSTALPNIMSDFKI
                     TADIGQWLTTIYLLIAGIIVPTTAYLINRFSTRKLFITSMSIFSIGCIIALFSNNFST
                     MLIARVLQAMGSGSLMPLLQVIILYLCPEEKRGAAMSLVGITVGFAPAIGPTLSGWLV
                     DSFGWHSLFLFLSPIAILDVILSFILLRNVGETQKLKLDIPSIVLSSLGFGGLLIGFT
                     NQGNYGWTNIATYLPILIGIMSLILFTLRQLKSKEPFLELRVFKNKPFLISTILIMIV
                     YASMMSATLMIPLYVQSVRGFSALSSGSLMLPGAILMVVLNPIAGRHLDKYGPHALSI
                     LGTGCLFLGTLSFAFLGRDTSLIHVSLMYCIRMIGISMVLMPLTTWGIKTLDRELISH
                     ATAINNTLRQISGAIGSAILITIMTSATKKAHMSSNMLSNIHGIDVAFSIAATLAFTG
                     LIVSICFIKRHQIIRS"
     gene            complement(9735..10625)
                     /locus_tag="ACGI5H_000611"
     CDS             complement(9735..10625)
                     /locus_tag="ACGI5H_000611"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861574.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HFG9696341.1"
                     /translation="MTEKQRLIITIAQKIFDQKGFQNTSISDVVKECKMSKATFYKHF
                     ETKESFICEIINYYDEKFLEIIHSINENNDIPSSEKLNRKIIAVWKNIFSRTTINTYI
                     RENFSEEQRKATSKLQTKSRANLLNEYKLSLFDNYGDKIEKIIFDLVFLLDALIHQFI
                     YIIHVQKREINVYFIAKFTIQILDLVVENMDNLNPLIEKSMFLHKQEDEVYFSLHNKS
                     LFFKTIQDIEELIKTDTSLLENPKLLEAIKKLYVEGKNQQYDSLIMDAMIAYLEKEDT
                     LRPKVLLLNSIKNQLKKETL"
     gene            10904..11551
                     /locus_tag="ACGI5H_000612"
     CDS             10904..11551
                     /locus_tag="ACGI5H_000612"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416477.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanyl-D-alanine carboxypeptidase family
                     protein"
                     /protein_id="HFG9696342.1"
                     /translation="MKKKICVAIIFALFIVFVEMFIDSSSEGSKIMTAELSKYRKGVN
                     VLSINNIIVANKKYSLPKDYSPQESSEARDAFYKMNKDAQKSGLNLKAFSTYRSYEYQ
                     DRLFKSYVKEHGEKEANRFSAKPGESEHQTGLAFDIGGDDQSCWANKKFNNTKEAKWL
                     YENAYKYGFILRYPEGKENITGYMYESWHYRYVGTEHSKNFAMNNLTLEEYLHIN"
     gene            11876..14515
                     /locus_tag="ACGI5H_000613"
     CDS             11876..14515
                     /locus_tag="ACGI5H_000613"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861573.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation-translocating P-type ATPase"
                     /protein_id="HFG9696343.1"
                     /translation="MSYKSTYQEVIKNLDSSLSGLSKERAEELLEKNGANELKEADKV
                     PTYKLFLESFKDPLVIILLIAALVQIFLGETVESIIIFAVIIINSVLGVVQTKKAESS
                     LESLKNLSAPNAKVIRDNKKMTIPAKNLVVGDIVFLEAGDYIPADGRLIEAQSLKVVE
                     GMLTGESEPVLKHIEKISEDVSLGDQKNMVFSGAVVVYGRGSFVVTGTGMNTEMGKIA
                     GLLESAENKLTPLQQKIEDFSKKLGVGIVILALLIFIIQVARNYFMAGNGEMTQIILD
                     SFMFSVAVAVAAIPEALSSIVTIVLAVGTNSMAKKQAIIRKLPAVETLGSTSVICTDK
                     TGTLTQNKMTVVDYYMYGTNNDELDKEKVNYSYHAKLLTMVSTLCNDSHITSDGKEVG
                     DPTEVALINYSSKNDLDYDKLRSKYIRINEIPFDSDRKLMSTVNSIYGDYIMFTKGAP
                     DIVFSRCKYALKNGSKVDITDEIIEEYKHKNEEFSNRALRVLAFAIKDVPEEDFIPSI
                     DDEHDMTLVGIMAMIDPPREEVMDAVKEAKSAGIKTVMITGDHKTTAAAIAKEIGIME
                     EGDLALTGKELDALSEEQLYEKLENISVYARVSPENKIRIVKAWQHKNNITAMTGDGV
                     NDAPALKQADIGIGMGSGTDVAKDASAMVLVDDNFASIVNAVEVGRTVYSNIIKSITY
                     LFAGNLGAIVSIVFAVFAGWSNPFTALQLLFINLVNDSLPAIALGFEKSEKNIMNKPP
                     RHPDESILAGGTLKAVAIRGCIIGVVTIIAQYIGLQVSPELGVAMAFSTLILARIMQT
                     LPARSNNQTVIKLGFFSNKYVIGAVLVCLGLYSLTLIPVLRGIFSIPTTFGLYQLGIC
                     LGLALISSILMELNKLINRSEVK"
     gene            complement(14573..15676)
                     /locus_tag="ACGI5H_000614"
     CDS             complement(14573..15676)
                     /locus_tag="ACGI5H_000614"
                     /EC_number="2.6.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416482.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004400 - histidinol-phosphate
                     transaminase activity [Evidence IEA];
                     GO_function: GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA];
                     GO_process: GO:0000105 - L-histidine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="histidinol-phosphate transaminase"
                     /protein_id="HFG9696344.1"
                     /translation="MKLKINKAIEMQLKKSYAIESGHSEDVFEIDCGEGINTVSYSNK
                     AVEAFNALKFDMIRGYPHSIALKDNIVDYWKDFIALDTDRICLADGSIHVIYLLNRLF
                     IEKGDKVLGYSPQFSEYETDIKMHGATYDYVLLKKEDNFKFNEKEFIEKINPEYKVIY
                     IDNPNNPTGQIIPLSSIENIVREAAKYDIAVMVDEAYGEYMPKENSAVKLLNNYDNVI
                     ALKTFSKGFGLAGLRAGYAVLPEQLVSPIKKISTPYEVSEISRSIAANLLDDVQFIEE
                     LKEKTKDIKNQLLIPWKNLNIAETSDTVSIMTVEHKNKDIDLQQEFAKLKIRVISGSD
                     FTGLDKNFIRFRMPEEKELPEVIKAFQIIDNIE"
     gene            16036..16857
                     /locus_tag="ACGI5H_000615"
     CDS             16036..16857
                     /locus_tag="ACGI5H_000615"
                     /EC_number="3.1.3.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454798.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HFG9696345.1"
                     /translation="MGYKLIVTDMDGTLLGNNHKVTDENKTALQKVIKSGINVTLATG
                     RAFDSAKCNVDFLKEDMPIIACNGSLIREQNGNIIYSNKIDTRTCLNILDVLDKYDIY
                     YQCNSIDSMLSKKIEGREDRLSVFLGSETEVIVKDDLREEIFKKDILKFVIIEEKNPS
                     ILDEIRKELRKVQGIKITSSWPNNIEVMNEGVDKGNAVKILAEKMNIDREDIIAFGDN
                     YNDIEMIKFAGLGVAMGNAEELIKQEADYVTDTNQDSGVAKAIYKFLELKESLSS"
     misc_binding    16936..17147
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            17234..18550
                     /gene="argH"
                     /locus_tag="ACGI5H_000616"
     CDS             17234..18550
                     /gene="argH"
                     /locus_tag="ACGI5H_000616"
                     /EC_number="4.3.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905936.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004056 - argininosuccinate lyase activity
                     [Evidence IEA];
                     GO_process: GO:0042450 - arginine biosynthetic process via
                     ornithine [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="argininosuccinate lyase"
                     /protein_id="HFG9696346.1"
                     /translation="MKLWGGRFRKAENQLMEEFNKSFGYDCVLYKKDIEGSVAHVHMQ
                     VKCGLLTEEEGKSITEGLKGILEDVENGKLVLDGEYEDIHSFTEINLIQRIGDVGKKL
                     HTARSRNDQVAVDMRLYAKEKANDLVDLISEFKATIKDVADKNPVMMPGYTHLQRAQV
                     VTFKHHLMAYYSMFDRDEKRIKNAIEILDESPLGCGALAGTTHDIDRSITCEQLGFKK
                     VVDNFMDGVSDRDYLLELMSDFSIIMMHLSRLSEELILWSSQEFGFVEIDDLYTTGSS
                     IMPQKKNPDGAELIRGKTGRVYGNLFGLFTVMKGIPLAYNKDMQEDKEGFFDSVHTLE
                     MCIQIMDRMIATLKVNEDKMKQAVKNGFLNATEVADYLVKNNVAFRDAHGIVGSIVIY
                     CEDNKKAIEDLTLEELQKFSDAFKEDIYDFIDYESILNKGIKKNLK"
     gene            18799..19137
                     /locus_tag="ACGI5H_000617"
     CDS             18799..19137
                     /locus_tag="ACGI5H_000617"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890712.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2325 domain-containing protein"
                     /protein_id="HFG9696347.1"
                     /translation="MNLLVIGGHERMEKDYMVMAKKKGYKTKVYTTMSSKLNNSIGKP
                     DAVVILTSTVSHKMSRTVESQAKKQDILIVRHKNSSKVAFNECLDMVDECLGNCSKCK
                     LKDKQKQKNI"
     gene            complement(19264..20553)
                     /locus_tag="ACGI5H_000618"
     CDS             complement(19264..20553)
                     /locus_tag="ACGI5H_000618"
                     /EC_number="3.4.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454794.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008236 - serine-type peptidase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanyl-D-alanine carboxypeptidase family
                     protein"
                     /protein_id="HFG9696348.1"
                     /translation="MKRNLSLLLICLLIFTSFLGSSNISFADNEPAIVAKHAVLMDYE
                     SGKILYNKDGNSKLYPASTTKVWTACLVLKEVKDLNQVIEIKDLPQIDGSSMYLKNGE
                     SFTVKQLLDALLVHSANDAAFVLARYVGGGNVQKFIDLMNSEAKKIGATNTHFNNPHG
                     LPDPNHYTTAHDMALIAREAMNNDTFRQIVKTKSLKFEATKAYPYERYFVNTNKFLTS
                     HDKITYKGQPINIKYDIVDGIKTGYTDAAGKCLLSSAVKDGRRVIVAVFNSTNADLYL
                     DSRILIDYGFDNFKCATIVDKEKYTDTKKVLFTKQHELIYEPKNSYRIFLEKDESQGN
                     YDTKTELNKIDLPIKKGAKVGTLNVYNNGKLENSIDLIAKNNLDSSLPFLTENNVLMT
                     FVKIIAGILVLLVLFIIASNIKKKKRKKARSKKNMKK"
     gene            20633..21337
                     /locus_tag="ACGI5H_000619"
     CDS             20633..21337
                     /locus_tag="ACGI5H_000619"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728771.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-hairpin-helix domain-containing protein"
                     /protein_id="HFG9696349.1"
                     /translation="MKKKVKFISFFVLFILIISSIIVYKSLIFKDDIYVVSKKNLPNE
                     KTHVVENEIKGEDNNHSKVTKDIDKNFQNNKITIYISGAVNRPGIVTIESDKRLYDAV
                     ELLGGTTKEADLNGVNLSVRLEDEQHYIIPKIGEATSVTSNDDSNKLNQKNESRGEPK
                     NKSNKNISNESKVNINVATIEELDSLPGVGEATANKILQHREENGQFSSIEEIKNVNG
                     IGDKKYENIKDLICVD"
     gene            21429..22475
                     /gene="selD"
                     /locus_tag="ACGI5H_000620"
     CDS             21429..22475
                     /gene="selD"
                     /locus_tag="ACGI5H_000620"
                     /EC_number="2.7.9.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015617929.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004756 - selenide, water dikinase
                     activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0001887 - selenium compound metabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_except=(pos:21477..21479,aa:Sec)
                     /transl_table=11
                     /product="selenide, water dikinase SelD"
                     /protein_id="HFG9696350.1"
                     /translation="MKKEQKKLTEMTTAGGUAAKIGPEVLASVLSQLPKNDNIENLLV
                     GLDTADDAAVYKLNDDMALIQTLDFFTPMVDDPYVFGQIAASNSLSDVYAMGGKPLVA
                     MNIVCFPSCHDMDVLAEILKGGFDKVKESGALLVGGHTVDDKEPKYGLSVSGIVSPNK
                     VLSNATAKPGDKLIITKPIGVGVLNTAMKEGMVEQHIADKVIEIMIHLNKYAAMSFEK
                     FDVNSVTDITGFGLLGHTLEMAKASEVSIEIESKHVPIIEGAIEMAQMGIIPAGMYKN
                     MHYVSKDVEVVGNIEVAVQDILYDPQTSGGLLISVKEELAEELVKDMKLNGAIEAKII
                     GSVVPKGEKYITVL"
     gene            22526..23905
                     /gene="selA"
                     /locus_tag="ACGI5H_000621"
     CDS             22526..23905
                     /gene="selA"
                     /locus_tag="ACGI5H_000621"
                     /EC_number="2.9.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430991.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0004125 - L-seryl-tRNA(Sec) selenium
                     transferase activity [Evidence IEA];
                     GO_process: GO:0001514 - selenocysteine incorporation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="L-seryl-tRNA(Sec) selenium transferase"
                     /protein_id="HFG9696351.1"
                     /translation="MLPSVDEVLSDNRIVEIINEYPRSLVLESVREVIDLKRQFILRL
                     KEDASNSVTIEFGEIIESAIERVKLNYSLSLKKVINATGTVIHTNLGRSLLSEDIKDE
                     LWCAASRYSNLEYDLDNGERGSRYSHLTSTIKRLTGAEDVLVVNNNAAAVLLVLSTMA
                     KGGEAIVSRGELVEVGGSFRIPSIMALSGAELVEVGSTNKTHLKDYKEAITEDTNVLM
                     KVHTSNYRIMGFTESVSIEELVNLGKKYKLPVIEDLGSGVFIDLSKYGLSYEPTVLDS
                     IRQGADVVTFSGDKMLGGPQAGIIVGKKEYIEKMKKNQLTRALRVDKLTICALEATLR
                     MYLDETKAIENIPTLKMLTYKIEELEVKANKLFEKITALNLNANINIEDGFSQVGGGS
                     MPLETISTKVISITPEHMNVSSLEKKLRLSEAHIIARVYDNKYVLDVRTIFDDEFDVI
                     VEELRKAFN"
     gene            24019..25902
                     /gene="selB"
                     /locus_tag="ACGI5H_000622"
     CDS             24019..25902
                     /gene="selB"
                     /locus_tag="ACGI5H_000622"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416497.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0003746 - translation elongation factor
                     activity [Evidence IEA];
                     GO_function: GO:0003924 - GTPase activity [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_process: GO:0001514 - selenocysteine incorporation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="selenocysteine-specific translation elongation
                     factor"
                     /protein_id="HFG9696352.1"
                     /translation="MKNVVIGTAGHIDHGKTTLIKALTGRETDTLDEEKKRGISINLG
                     FTYFDLPNNRRAGIVDVPGHEKFIKNMLAGASGIDIVLLVVAADEGVMPQTVEHLDIL
                     SFLNIKNGIVVLTKSDTVDDEFRELVKEDICEKIKGTFLEDAEIIEVDSISKRGIDTL
                     IEKIDKMSDDIEDKNENSPARLNIDRVFSIKGFGTVITGTLIEGKISIEDDLVIYPQV
                     LKTKIRSIQVHGENKDTAYAGQRTAINISNVKVDDIKRGDVLAAPNSLEESMMLDVKL
                     SLVNHLDKGLKHWDRLRLYHGTREILCRAVPLDKELIESGESGYVQLRLEESIVSKKG
                     DTFVVRRYSPMETIGGGVIIDPSPKKHKKFDEKVIEALKIKEKGELKDIIEEYLKRNL
                     KNYPNIKEIMSYSGAHEEDVKRALETLISEDKVFIIGNMYMHINQYNKLKENTIKLLS
                     EYHKKYRLRKGILKEEVRSKIESNFKTREMDILLEKLSTENAIKIENNIVSLLDFEVI
                     LNDKQKEIAKKIEKRLKSCGVSSILTIDEVSEGNHNYAEVLESMIGNKVEKLDDLYIM
                     DKDIYENAKNILINYIKENKEITLGEYRDLIDSSRKNCMIILENFDRNKITKRVENKR
                     ILF"
     gene            26007..28745
                     /locus_tag="ACGI5H_000623"
     CDS             26007..28745
                     /locus_tag="ACGI5H_000623"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454784.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sporulation-associated two-component system
                     sensor histidine kinase"
                     /protein_id="HFG9696353.1"
                     /translation="MKNIIPDVKPDIKEREDMSLLFIIMGSVLLLFIIKDIEKYETLL
                     HAIYTIFLVATGVIIFNTTKFKVDSFSTFLGLIFIATGVLECIYLFNSLGIKTKSIME
                     INITISAITDLFPILGVYLSFKFVKDNKQIYSSVILFIATATLTITSLFIISGICDYL
                     GNGKSQYALGVIISIFIIIISIISGIELNSSSNKGKWEYDEKKIFNRIIVIIILSRVP
                     NLLHIVIDNRNVERILSQIIINVALYYLYNYIVSKNIKKTALELHDTNEELTKKTESL
                     KEKNKKLIYETEKIEELKGILMKRESRLQSTLDVAVNSIVVFSKDGEITYANKSFRNT
                     FGDYKEQDKLTDKIKNFNDLIESIHYVFVHEKNAEKLISTSDNKVYQAIFAPLIIASQ
                     TEGVLCVLEDKTKKKEYERKLIEANKRSKDFLESIGDGIVVLEGNNKIYVNNACREIF
                     KNNLESIDFSLVCKSEESIEKRYVIDGEVKYVEMSFSQYTNAGTNKTIIVIRDTTSRK
                     ISQIKLEESQSSYSRFIDILPDGICLLKEDLSINYANKSFLDMLAFTNIDDIKDSNIK
                     LLMNANTEEKMKFTDNMAKVLNENRSILLLEHELINSYDDIVEVELSALPFAIYNTRY
                     IMLIIKDLVHKKYSEQAEKELLERFKTDKIKTEFFANMSHELKTPLNVISSSNQLVDS
                     FYRNEKIKDYNNNIKSHVDLVRQSSYRLQRLINNIIDLTKMESGFYTLKLAKYNIVSV
                     IEDLFMNIEEYALRKDIKILFDTDLEEINVYIDKVEIERIMLNLLSNCIKFTDNGGWI
                     YVSIHYKIDKVIISVKDTGVGIPQDKLELIFEEFSQVDKTLSRNTEGSGIGLAIVKNL
                     VSLHGGDIEVVSEVNKGTEFLISLPMKGFSSEHYTEDKRIYNIQEKIKIEFSDIYY"
     gene            complement(28864..29808)
                     /gene="manA"
                     /locus_tag="ACGI5H_000624"
     CDS             complement(28864..29808)
                     /gene="manA"
                     /locus_tag="ACGI5H_000624"
                     /EC_number="5.3.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430987.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004476 - mannose-6-phosphate isomerase
                     activity [Evidence IEA];
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="mannose-6-phosphate isomerase, class I"
                     /protein_id="HFG9696354.1"
                     /translation="MEPLFLKPIFMDRIWGGTALKDKFNYEIDSPTTGECWAISSHKN
                     GDCLIENGKYKGKKLSELWNKNRELFGNTPGDKFPLLTKILDANDNLSVQVHPNDEYA
                     KKNENGELGKTECWYVIDCSDDAEIIIGHNAKSHKEFVNMVNNNEWDKLLRKVNIKKG
                     DFFYVPSGTIHAICKGTLILETQQNSDTTYRVYDYDRTDNSGNKRELHVQKSIDVTNV
                     PHINFDTDYKIVSTSDFKCTTFVSNEFFSVYKLDVFGKCNFTHNTPFSLYSVLDGNGK
                     LIHNSVEYNLKKGMHFILPNDFGDFSFEGNLEIICSHI"
     gene            29981..31342
                     /locus_tag="ACGI5H_000625"
     CDS             29981..31342
                     /locus_tag="ACGI5H_000625"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728775.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M20 family metallopeptidase"
                     /protein_id="HFG9696355.1"
                     /translation="MELFKAESKKYKKEFLKLLEQWVSIPSFYDRKTVSKDMPFGKGV
                     YDALNWFENLGRENNFKVKNIDNHAVQIEYGNGKEYVDIFGHCDVVNPGEGWDSEPFK
                     LNIIGDKLVARGVSDNKGPMIVNFLALKMIKDLDINLKRKVRLIAGGNEESGFKCIKH
                     YYSKEPYGVCGFTPDAKFPVLNGEKGGAIIKLISNIDDKSLYISGGIEFNTIPDKVYI
                     KNVEKLGKDNICFDINNISINYDNGNYIVYGKGGHSSKPEKSINPILATIKLLSENID
                     EKWTKDLYKLINQDNINGNLFGLNIEGKCGILSMVPTIINIVDGKLEVVLSVRYPEIL
                     TIEDIIKKFNLYMEQNNINKFELIGENLKQANYIDRNSKLVRSLHDIYIKYSGDLKND
                     VRVTSAGSYASEMNNSVIFGCEFPDGSFGNVHSANEFASLDRFITAIGIYAEAIITLC
                     NKI"
     gene            31430..33319
                     /locus_tag="ACGI5H_000626"
     CDS             31430..33319
                     /locus_tag="ACGI5H_000626"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890703.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antiterminator"
                     /protein_id="HFG9696356.1"
                     /translation="MITKKHAIIVKSLSNKDGYMTSNELAIKLDVSTKTIKRYIADLN
                     SVLSKYDLVIASSRGIGYKLSGSKNNIARAVKEANKYIDGFLDDSEESRMSNIICMLI
                     NRNYMSIEAMAEELNLSIAAINKLSSKLKRKLEKYDLVIKSKPYYGSYIHGEEINIRQ
                     LITDYAIKLDEKSKVKVFLDDISENDIHCIESILEKHLREKDTIISDKDFNLLLSKII
                     VSVFRSKRGHSNNINLMDTSYRFHNYYFIENLMKEISDKIGFKLIEDEVIYISNYSGV
                     IAYKGTQGRKNTSEIEERISSVISSALQDIFLISGSDYTKDDEFMVAISDHIKRFLNR
                     ARANVKSNNPLLHQIKEKFPIAFNLAVFLSNKLETEFNLKLDEDELGYIAIHFAASNE
                     RMKKNTSKKICIVCHYGIGTGQLISEKLKQNISDLSVVGVYPVRYLDMAISQDVDLIV
                     STVELKGYEKPVLYIENIFDDSLIENVNKAFYEKEERRKIISNMFDEKAFFSIKANTK
                     EEVIISLSNKLKERDFIEESSIKSIIDRENISSTEIGNLVAIPHTIVKGDKKSIIGVG
                     ILENPIIWDKQEVQLVFMVFFNTKEKHNFSIFKYLYNFIKDEGGVRGIIKICDFNKLM
                     ALIGN"
     gene            33334..33789
                     /locus_tag="ACGI5H_000627"
     CDS             33334..33789
                     /locus_tag="ACGI5H_000627"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430982.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:1902495 - transmembrane transporter
                     complex [Evidence IEA];
                     GO_function: GO:0016301 - kinase activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA];
                     GO_process: GO:0016310 - phosphorylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HFG9696357.1"
                     /translation="MGTNIFNKEYVFLNVDAKSKVEVLKFISKKAKDLNLAEDESLVY
                     EGLMAREEQFTTNLGESIAIPHTKNDAIENPAVVVLKFNEDVVWNEGEDKVKLAISLL
                     MPGKSKENIHLKLLSSLSRKLINKEFKDSLLKSDNVEEISNLINEALGL"
     gene            33848..34165
                     /locus_tag="ACGI5H_000628"
     CDS             33848..34165
                     /locus_tag="ACGI5H_000628"
                     /EC_number="2.7.1.202"
                     /inference="COORDINATES: protein motif:HMM:NF014368.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016301 - kinase activity [Evidence IEA];
                     GO_function: GO:0022877 -
                     protein-N(PI)-phosphohistidine-fructose phosphotransferase
                     system transporter activity [Evidence IEA];
                     GO_function: GO:0090563 - protein-phosphocysteine-sugar
                     phosphotransferase activity [Evidence IEA];
                     GO_function: GO:0090582 -
                     protein-phosphocysteine-D-fructose-phosphotransferase
                     system transporter activity [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA];
                     GO_process: GO:0016310 - phosphorylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS fructose transporter subunit IIB"
                     /protein_id="HFG9696358.1"
                     /translation="MNKKLVALCACPMGLAHTFMAAEAIEQAAKALGYEAKVETQGAD
                     GVQNELTRDDILGATMIIHAVAITPEGMERFDGCEVYEVELQEAIKNAEGVIKEIEED
                     LGI"
     gene            34190..35452
                     /locus_tag="ACGI5H_000629"
     CDS             34190..35452
                     /locus_tag="ACGI5H_000629"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728777.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS fructose transporter subunit IIC"
                     /protein_id="HFG9696359.1"
                     /translation="MAIKKKVINSSGASTTGGNNVGKSTPSSPTQSKGNGKWKEISKH
                     IMTGISYMIPVLVMGGLIGALSQLIPYAILGLDPSVGIVDAMNSGEFTGFKLSLLNIA
                     QLMSNFGFTLFGFAIPLFAAFCANSIGGKTALIAGFIGGYIANKPVGVPQFVDGQWTE
                     VVPVASGFLGAILIAFIIGYFVKWLNKSIKVSHNWLAFKTTFLIPLIASLACMVLMIF
                     IITPFGGLINESMKNFLTAAGAAGEYVYATALAAATAFDLGGPINKAAGFVALGLTTE
                     NVLPITARTIAIVVPPIGLGLTTLLDKRLVGRRVYDRQFYQAGKTSIFLSFMGISEGA
                     IPFALERPGFVIPLNIVGSVIGAITGIILGAIQWFPESAIWAWPLVDNLFGYIIGIAV
                     GAIFIAVGNIFYRNKLIKDGKLVVDYID"
     gene            35557..36621
                     /locus_tag="ACGI5H_000630"
     CDS             35557..36621
                     /locus_tag="ACGI5H_000630"
                     /EC_number="3.4.11.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893615.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004177 - aminopeptidase activity
                     [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_function: GO:0070006 - metalloaminopeptidase activity
                     [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase P family protein"
                     /protein_id="HFG9696360.1"
                     /translation="MDKIEKVREYFREYDIDGFLINSPTNKFYVGNLFSSSGYVFITK
                     ESQYIIVDFRYFEEIKRKSSLFNVVLMDKTRTHFDIINDICREQNIKEIGFEGNEVSF
                     DLYRSMSNKLSATLKSVDLSTLRETKNEDEIKYIKKACEIVDATFYHIVDFIKVGMTE
                     KQVENEIVRIIKDLGGQKESFDTIVASGLRGALPHGKASEKVIEYGDFVTFDFGAKYN
                     NYCSDITRTICMGTINKELEEIYNIVRKANEECIRVLRPGMTTGEIDKVARDIIGSYG
                     YAGNFGHNLGHGVGIMVHEYPALAPESNEVLKEGMIVTIEPGIYVPSLGGVRIEDDVL
                     ITQDGCMRLTTSTKDLIVVS"
     gene            36675..37853
                     /locus_tag="ACGI5H_000631"
     CDS             36675..37853
                     /locus_tag="ACGI5H_000631"
                     /EC_number="4.4.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA];
                     GO_function: GO:0047804 - cysteine-S-conjugate beta-lyase
                     activity [Evidence IEA];
                     GO_process: GO:0009086 - methionine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MalY/PatB family protein"
                     /protein_id="HFG9696361.1"
                     /translation="MYNFDDKPDRVSEKCRKWDLNIIRDKFGDIREDFIPMWIADMDF
                     KIPTEIENKFIEAVRRGVFGYTYCYDEFYDSVIGWQKNMHEVNVEKEWITLTYGTVST
                     LHYVVQAFCKKGDSIILNTPVYDPFESSAKKQGVNVICNTLDVVNDRYYINFDKLEVQ
                     IKENKPKLMMFCTPHNPSGRIWTIEEMTRVATICKENNVILVADEVHAEHIHYGTFNS
                     ILKIGKELLENVILLTSPNKGFNLGGLKTSYSIVINKDIRDKFRNKLKQNSITSPNVF
                     GIIGLITAYNECHEWLSGVNEYIKSNYELLETWVNKYNKIKLMKMESSYLAWMDISGL
                     GISASEFTDKLAIDTGVLLEDGSHFVKDGEKYVRINLGTQKENVIEALNRMDLFLKSL
                     "
     gene            complement(38044..39102)
                     /locus_tag="ACGI5H_000632"
     CDS             complement(38044..39102)
                     /locus_tag="ACGI5H_000632"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893613.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_function: GO:0016740 - transferase activity [Evidence
                     IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0017013 - protein flavinylation [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="FAD:protein FMN transferase"
                     /protein_id="HFG9696362.1"
                     /translation="MNKKKITFIFVILILALILFSFFRSSSQNTKYSKTSYYLGTVNE
                     VTVFNVKESKSDKILNECDSILRYIDNKMSTHIPGSDVSKINDNAGKKFVRVSDDTFF
                     VVKEAIQYSKLSDGYFDITIGPLSNLWAIGTDKAKVPSDSEIQKLLPLIDYKNIILDE
                     KNKSIKLTKENMKIDLGAIAKGYAADKIVAYLKSEDVKKGLVNLGGNIFTLENGKNDK
                     PFKIGIQDPTSKNGESIGNIETTNKSVVTSGIYERFIEKNGKIYHHMLNPFTGYPFEN
                     NLSSVTIISDKSINCDALSTSTFGLGLEKGMNLINKIDNVDAIFITKDKKVYLTKGIK
                     DNFKLTDKSFSIEKLNKQ"
     gene            39169..39540
                     /locus_tag="ACGI5H_000633"
     CDS             39169..39540
                     /locus_tag="ACGI5H_000633"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890696.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NusG domain II-containing protein"
                     /protein_id="HFG9696363.1"
                     /translation="MKKKDILLILGILVVITACYGIINVINSKNAGNIEIYVDNKLYK
                     TVSINAKEEFKIENRGGYNIVKIHDKGVEIVDASCPDKVCVHTGFINKPSQSIVCIPN
                     RVSIKINTNEKNDNQEDIISK"
     gene            39577..40251
                     /locus_tag="ACGI5H_000634"
     CDS             39577..40251
                     /locus_tag="ACGI5H_000634"
                     /EC_number="3.2.2.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416528.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004844 - uracil DNA N-glycosylase
                     activity [Evidence IEA];
                     GO_process: GO:0006284 - base-excision repair [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="uracil-DNA glycosylase"
                     /protein_id="HFG9696364.1"
                     /translation="MVNLGNDWDELLKEEFEKDYYLNLRKFLIEEYKTRQIFPNMHNI
                     YEALKHTSYKDTKVLILGQDPYHGDNQAHGLAFSVQPQVKTPPSLLNMYKELKDDLGC
                     FIPNNGYLMPWADQGVLLLNTALTVRAHEANSHKNKGWEIFTDRVISILSEREDPVIF
                     VLWGSNARKKVELIDTSKHYILEAPHPSPLSASKGFFGCKHFSKINEILKKLGKEPIN
                     WQIENI"
     gene            40500..41339
                     /locus_tag="ACGI5H_000635"
     CDS             40500..41339
                     /locus_tag="ACGI5H_000635"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454771.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="G5 domain-containing protein"
                     /protein_id="HFG9696365.1"
                     /translation="MNFKKLSNAKVSVMAVVLSVGILSGYSALNKQVTLVVRGEERTI
                     STFSSNVGDLLESQNISYDANDIVTLDENTKLSNGDKIEVIDVKEKTVVETKDIPFEV
                     TVVEDGSLLKGDSKVKEEGKSGKSELIYKETYHNGKKVEKEFVKKVVKAEPVNKVVSK
                     GTKVEMQVASSRGESSRRMASSSSSSSSSNNGKNMRVVATAYTGHSITATGTKPKWGT
                     IAVDPKVIPYGTKVYIPQFDMVFTAEDCGGAIKGNKIDIYMNDSKTVYNWGRKTIDIR
                     ILK"
     gene            41583..41679
                     /locus_tag="ACGI5H_000636"
     tRNA            41583..41679
                     /locus_tag="ACGI5H_000636"
                     /product="tRNA-Sec"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:41617..41619,aa:Sec,seq:tca)
     gene            41829..42536
                     /locus_tag="ACGI5H_000637"
     CDS             41829..42536
                     /locus_tag="ACGI5H_000637"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416532.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008641 - ubiquitin-like modifier
                     activating enzyme activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ThiF family adenylyltransferase"
                     /protein_id="HFG9696366.1"
                     /translation="MENNFTTRTSFLVGDDGIEKLNNSNIIVFGVGGVGSFTVEALAR
                     AGVGNITIVDFDDVDITNINRQIPALHSTVGRYKVDVMEERILDINPNINIKKIRSLY
                     NKDTSDEILTERYDYVVDAIDMVSSKIHLIETCEKKGLKIISSMGMGNKLDPTKIVVT
                     DIHKTSTCPLAKVMRKELRDRGIKKLKVVYSTEQPIELKKKVMNGRKVTPGSVSFVPS
                     VGGLIIASVIVNELLGQ"
     gene            complement(42678..43514)
                     /locus_tag="ACGI5H_000638"
     CDS             complement(42678..43514)
                     /locus_tag="ACGI5H_000638"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861569.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HFG9696367.1"
                     /translation="MRNKIFLSILIIISLLIGCDKKSLLSIHMIDVGQGDSILVQTPT
                     NKNILIDGGDEDSENIIISYLRQKRIKTIDIIIATHPDSDHIGSLDNIIKKFNVNSIY
                     MPEQSTDSEAYQNLINSCTDKNLSIQHLYKNDVLNIDNNINIYVLSPSYIQEESNLNS
                     IVFKLTFNDNSFLFMGDAEEENEKEILHSFKLNNINFIKIGHHGSNSSSSLEFIKKIS
                     PDIAAISCGYKNQYGHPHREVINNLKQNHVSIYRTDRIGDIVFYSDGEIIFTKYNYEI
                     DT"
     gene            43702..44607
                     /locus_tag="ACGI5H_000639"
     CDS             43702..44607
                     /locus_tag="ACGI5H_000639"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454768.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatidylglycerol lysyltransferase
                     domain-containing protein"
                     /protein_id="HFG9696368.1"
                     /translation="MFFKDIELNSKKELDPYFDLVDYEACEYCFSTLYMWQHVYKTGY
                     YIGEDFAVLVGEYEGDSFSILPLAKKDKLPEVVDFVLEYFSKNNKKIYLRGITTEVVE
                     FLKEKYPGRFEYIEERDLFDYIYDAESLRTLAGKKNQKKRNHINYFLKEYAGRYEAKL
                     LDKENFDECLVLMKEWESNKEENNEFDESMDDELIGIKKIFNHYDILKDKVKVFGVYV
                     DGKLEAFSIGELLNPNMALIHIEKANPDIRGLYPFINQQFLVSEFKDVEFVNREEDLG
                     IEGLRKAKLSYHPCRFVEKYSVREA"
     gene            44616..45800
                     /locus_tag="ACGI5H_000640"
     CDS             44616..45800
                     /locus_tag="ACGI5H_000640"
                     /EC_number="2.3.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893611.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HFG9696369.1"
                     /translation="MEIRYAKEEEIESIKEIWSYCFNDTESFMKYYFNDKYKSENTVV
                     ALDEGKIISSLQLNQYKLLLNSKVYNTSYVVGVSTLPEGRGAGYMNKVMKFTLNELYK
                     KGQLVSILMPIDYRLYRRFGYEHCYDQIEYTINTDDLKNFKSSGKMIKSNLSQIDDLI
                     QIDRTFLNEVNGNVLKDEHYYENLFKEIQSEDGFLYIHEGNEKDGYIVYFLQEDKMFV
                     RELFYKNIDALKSMLKFIYNHNTQCKIVTISTPTIDKIRFILDNPKDSDIKIKPFMMG
                     RVINVKKFIEDIDIENDINSSFNLLIEDKFIDENNGLFKISIQNKKVSVEQLDKKGAE
                     KPQEDFDIKLDINTLTQLSFSYIDVNEAIFLNDIKDVSEETLETLNCIFSKKNNYINE
                     YI"
     gene            45915..47216
                     /locus_tag="ACGI5H_000641"
     CDS             45915..47216
                     /locus_tag="ACGI5H_000641"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_process: GO:0030420 - establishment of competence for
                     transformation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ComEC/Rec2 family competence protein"
                     /protein_id="HFG9696370.1"
                     /translation="MGVIIIQIRRPLLIILMFVVAISFIITNNTKNDEELNDKIITIQ
                     GVVKGKIEKKRYNQYKVGVFLINDYTKNKNLKIGQKVNITGKFKSLDKMKYDDFDYGR
                     YIKSTGYKGIVYINNYKIIDKNKLYSLIGEIKFYISKTYRYLYKKNSDFINSILLAEV
                     ENLTEEQKEIFTRTGTSHVISISGLHTGILCVIISFLLRGINKLYKLLILSIFITLYC
                     IMVGASPSIIRSIAFVMIFYLSIFIDRKKDGISALSLIGIILIMNNPYVIYNVSFQLS
                     FLATLSILIFYNKINSIIKLSMVSLTISSNILTLPIIYYTFKGIPLLSIIGNLIIVPF
                     VGVIMYLSIASLIVFKVSVVIAKIISFFNSTFIESIFFLLEKISNLSFAYINIENPKF
                     YIVVIYYIGVFFYIFYIEGKEIKEQENELQGYYKECKREKL"
     gene            47170..48213
                     /gene="holA"
                     /locus_tag="ACGI5H_000642"
     CDS             47170..48213
                     /gene="holA"
                     /locus_tag="ACGI5H_000642"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416543.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003887 - DNA-directed DNA polymerase
                     activity [Evidence IEA];
                     GO_process: GO:0006260 - DNA replication [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit delta"
                     /protein_id="HFG9696371.1"
                     /translation="MNYKDIIRNVKEKNFEKMYLFYGREYYLIENAIKAFKDSLNEGM
                     LDFNLDIIDGKEIVLNQLISSIETLPFMDDRKIVIIKDFELLKGKKKNFTDSDEKYLI
                     EHLDNIPDTTTIVFVVYGDVDKRKSLVKKIGNNGIVFDCDKLSDMDLFKWIKKSFALN
                     DVIIDNSQIMYFIEQEGYRDKSSEKTLSDLENEINKISSFVGKGNNVTNDVIDKLSQK
                     KVENDIFKLIDYIGEQNASNAMKILNDMIQEGESVLGIFSMIARQFKIIMQVRQLQLD
                     GYSTKLIADKLKMHQFVVGKALKQTKNFSDDIIVEILNYILESDYKIKTGLIRDTLAV
                     EMLVSRYCKREAI"
     gene            complement(48400..48666)
                     /gene="rpsT"
                     /locus_tag="ACGI5H_000643"
     CDS             complement(48400..48666)
                     /gene="rpsT"
                     /locus_tag="ACGI5H_000643"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890686.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S20"
                     /protein_id="HFG9696372.1"
                     /translation="MANIKSAKKRISVIEKKTALNRVRKSQIKTAIRRFEDAVAAGNR
                     EDAVAKFQYAQKRIYQVASKGTIHKNAAARKVAKLAQKLNGMNA"
     gene            49244..49765
                     /locus_tag="ACGI5H_000644"
     CDS             49244..49765
                     /locus_tag="ACGI5H_000644"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454764.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HFG9696373.1"
                     /translation="MDIAKLILNPARLRILQYIRLYGSVRTSDIVKYLNDIPRATVYH
                     HVKILEENNMIEVIKENRVRGTIEKVYALKEYTTSMEGETFVALSTAFYVGLMQEMNE
                     YFSRKEQDHKKDNVFFSSALLYMSDNEYENLLKSIADLLKPYIEQKPKSNLKLRKLSI
                     ISSPPVADNDKTK"
     gene            49799..50575
                     /locus_tag="ACGI5H_000645"
     CDS             49799..50575
                     /locus_tag="ACGI5H_000645"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890682.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta fold hydrolase"
                     /protein_id="HFG9696374.1"
                     /translation="MKFHEFGNKNRPHIMLIHGGGNAWWNYLRQAEVLSNKYHVILPT
                     LDGHGEEYETTYISTEDTADKLISYIDENCSGHLFALCGVSLGGQIVMELLSRKPNIT
                     KKAIIDGSICYPRPLMARFCIAGIRFFGGLLFSEKACRFQIAMMPKLLPENMQYPDKI
                     KAYYMTDMPHVRKETFYNMYRTYMMNYTLKENVKKTTAQVMYWYGEKEMKCVKKSAKL
                     FQSYVPSCEIYEAKSYNHGYLSLYLPNEWLEIAEPFFQKE"
     gene            50917..51870
                     /gene="gpr"
                     /locus_tag="ACGI5H_000646"
     CDS             50917..51870
                     /gene="gpr"
                     /locus_tag="ACGI5H_000646"
                     /EC_number="3.4.24.78"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430954.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004175 - endopeptidase activity [Evidence
                     IEA];
                     GO_process: GO:0030436 - asexual sporulation [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GPR endopeptidase"
                     /protein_id="HFG9696375.1"
                     /translation="MISVRTDLALEASEMCEKSQEGSSIPGVKIETKELENCIVTKVE
                     VIDRQGAEIMNKDIGKYITLESNLMKFDDDESREEMISYLKEELVDIFGQDKNKKTLV
                     IGLGNRNITSDALGPKSVSKTLVTRHLFKNYNKDYDDDFTEVSALSPGVMGVTGIETS
                     EIVKSLVEKVKPDRVVAIDALASRKMERVNSTIQISTAGISPGGGVGNTRKSLTKETL
                     GVDVIAIGVPTVVDAATLTIDVLDMAIDNLIAQSEETESFYEMLKKLKEEEKYHLIKD
                     SLDPYDKNLIVTPKDIDDTIENLSIIISEGLNRSLHPGRLV"
     gene            51888..52907
                     /gene="spoIIP"
                     /locus_tag="ACGI5H_000647"
     CDS             51888..52907
                     /gene="spoIIP"
                     /locus_tag="ACGI5H_000647"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897656.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0061783 - peptidoglycan muralytic activity
                     [Evidence IEA];
                     GO_process: GO:0030436 - asexual sporulation [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="stage II sporulation protein P"
                     /protein_id="HFG9696376.1"
                     /translation="MFKKCIKVVTLTFILVCILPGKSLALNQDDFLKFLVNSSYPEAK
                     VEGNDTENKKNNKNKETSKENKEESKEGNTKSKDASKVDNKKESEKEYIKLYVGKENV
                     PDIESKNSDTTETNTTSSSDYKDDLRVTKENPRILIYHTHGCETYSNSPDGNYHSRDK
                     KNSVMEVGSALTSALDSKGWGVVHTTKYHDYPSYNNSYASSLKTIQSILPKYNSVDIA
                     IDLHRDARDLTNPATKEKDHLKYTTMINGERVSKFFFVVGGKNTNRKQLRALAEDITA
                     FAEKKYPGLVSPIVEKDYARFNQFAVKNHMLVEIGNNATSVEESKATTKYLAEILDEY
                     FKQKN"
     gene            52938..53189
                     /locus_tag="ACGI5H_000648"
     CDS             52938..53189
                     /locus_tag="ACGI5H_000648"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430948.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9696377.1"
                     /translation="MSRLEKNIESKSKLRKYKYIMRILFLITMIICTSVCVFIVDSNA
                     KSMLGMKQYDFPSIKFDITKFDFDIPNFDIHEIIKKFNK"
     gene            53471..55276
                     /gene="lepA"
                     /locus_tag="ACGI5H_000649"
     CDS             53471..55276
                     /gene="lepA"
                     /locus_tag="ACGI5H_000649"
                     /EC_number="3.6.5.n1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430946.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003924 - GTPase activity [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="translation elongation factor 4"
                     /protein_id="HFG9696378.1"
                     /translation="MDNKQSRTRNFSIIAHIDHGKSTLADRLIQQTGLVSERDMKSQL
                     LDNMDLERERGITIKLQNIRLMYKAKDGNEYYLNLIDTPGHVDFNYEVSRSLAACEGA
                     LLVVDAAQGVEAQTLANVYLAIDQDLEILPIINKIDLPSARPEEVKNEIEDLIGLDSS
                     EAPLISAKTGLNIEDVLEDIVKNVPPPKGDNEAPLKALIFDSYYDAYKGVVAYVRVFE
                     GTVKKGMTIKMMNTNKKFEVTEVGVMAPGQTELSELSAGDVGYIAASIKDIRSCRVGD
                     TITDSNNPTEEPLPGYKKATPMVYCGIYPGEGEKYENVRDALEKLQVNDAALEYEAET
                     SAALGFGFRCGFLGLLHMEIMQERLEREFNLDIITTAPSVIYRVTKMDGEVVMIQNPA
                     NLPEPSEIKMIEEPIVKGDIIVPKDYVGVVMELCQERRGNMLNMEYIDDRRVMLHYDL
                     PLNEVVYDFFDALKSRTRGYGSLDYEVKGYVASTLVKLDILINKEQVDALSFIVHETR
                     AFPRGKAMCEKLKGEIPRHQFAIPIQAAVGNKVIARETISALRKDVLAKCYGGDISRK
                     KKLLEKQKEGKKRMRQIGSVEVPQKAFMSVLKLDE"
     gene            55425..56762
                     /locus_tag="ACGI5H_000650"
     CDS             55425..56762
                     /locus_tag="ACGI5H_000650"
                     /EC_number="2.7.7.72"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897653.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016779 - nucleotidyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0001680 - tRNA 3'-terminal CCA addition
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="CCA tRNA nucleotidyltransferase"
                     /protein_id="HFG9696379.1"
                     /translation="MINIEIPKKVDYIIKELEKNGYEAYIVGGCVRDCLLERVPNDWD
                     ITTSARPEVVVELFEKTIPTGIQHGTVTVMIEHEPFEVTTYRIDGNYSDGRHPDSIEF
                     TNNIVKDLSRRDFTINSIAYNSKTGLVDPFNGYEDIQNKYIRCVGNPVDRFEEDALRM
                     LRAVRFSAQLNFKIAEGTKQSIHKKADLIKNVSIERIQTEFNKILVSDSSKLNLLKST
                     GLLKFIIPEICELEDVTQHNPYHIYDVQKHTLIATEVIEDELYLKLTMLFHDLGKKVT
                     KTTDKNGVDHFYTHSRESVKIAKKILKRLKYDNYTINKVLILIQYHDYRIEPKRKIIK
                     KLLNKLEDVELFEDLIKVNWADTLAKNPKYAKQKILNLIECEKEFKHIINQKECFNLK
                     DLAINGKDLISIGIKPGKDIGYILNKMLEIVINNPELNEKEILKEKALNIYTF"
     gene            56995..58308
                     /locus_tag="ACGI5H_000651"
     CDS             56995..58308
                     /locus_tag="ACGI5H_000651"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="APC family permease"
                     /protein_id="HFG9696380.1"
                     /translation="MHTQLQKTIGLSAALSTVVGMVIGSGVFFKPQAIYTTTNGAPGL
                     GIIAWLLGGFITITAGLTATEISAAIPKTGGMMIYIEEIYGEKLGFLTGWMQTVLFFP
                     GTSAALGVIFAQQASELLGMSPNNMANVLPIAIGVILFLALLNIIGSSLGGKVQTVAT
                     IGKMIPLILIIVFGFIKGQSSEVLNPFVGDGVNASNALGQVLIATLFAYDGWINVGAI
                     SGEMKSPEKDLPRAIVGGLSLVMAVYIIINIAYLWVVPASELATVTSPATLVATRLFG
                     NIGGKVITVGILISVFGTLNGYLLTGSRIPYTLAEMGTLPASKTLLKVNSGGSPVNSI
                     LLITVLACVYALSGQFNLLTDLTIFSIWVFYVLTFIGVMRLRRQKPDLHRPYKVPLYP
                     IIPIIAILGGLFVIINQILTSTVISLGGIFITLLGLPVYYYMKKR"
     gene            58480..59655
                     /gene="hemW"
                     /locus_tag="ACGI5H_000652"
     CDS             58480..59655
                     /gene="hemW"
                     /locus_tag="ACGI5H_000652"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416563.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0051539 - 4 iron, 4 sulfur cluster binding
                     [Evidence IEA];
                     GO_function: GO:0051989 - coproporphyrinogen dehydrogenase
                     activity [Evidence IEA];
                     GO_process: GO:0006779 - porphyrin-containing compound
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="radical SAM family heme chaperone HemW"
                     /protein_id="HFG9696381.1"
                     /translation="MLGLYVHIPFCVKKCKYCDFNSYKMDIDSKKRYIEDLKIEMELY
                     SNKLYKDNKYKNKECCSLNKNDKITSIFVGGGTPSILTSDEIREVFISIKEMFDIDEN
                     AEITIECNPGTLTLEKLKTMKEIGINRLSIGLQAIQEKHLNFIGRIHTYEEFEKNYKD
                     ALSVGFKNINIDLMYSLPNQTLCDWKETLEKVVHLNPTHISAYSLILEEGTELYNMYE
                     SNKFELIDENVDIEMYEYTINYLKSKGYNQYEISNYSKEGYNCEHNILYWECEHYIGI
                     GAGASGYINENRYNNVESLEDYHLSLVKREKPIQENEILSEKDMIEEKIFMGLRMNKG
                     IKFEDFKKKFGIDFREKYNKQIEMLLARKLINQSFEGIQLTQKGREISNSVFIEFME"
     gene            59758..60777
                     /gene="hrcA"
                     /locus_tag="ACGI5H_000653"
     CDS             59758..60777
                     /gene="hrcA"
                     /locus_tag="ACGI5H_000653"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416565.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="heat-inducible transcriptional repressor HrcA"
                     /protein_id="HFG9696382.1"
                     /translation="MELNERKLNILKAIVKDYIETAEAIGSRTISKRHDLGVSAATIR
                     NEMADLEELGYLIQPHTSAGRVPSEKGYKLYVNSLMSKSELDDNDKILIEQCMNHNIN
                     HIKELIHETSKLLSQLTNYTTVAVTKSLINQSVIKHIQLVAMNDNNILLIVVTDKGDL
                     KKANLTTNVYLDQSKLNLISDNLTRKLLGKSITDLDDNLIAFIKYEISEYSGLIDELL
                     NALNSNMKEEDFSLSLNGATNIFSYPEFNDVLKAKSFLNMLEKKETIADIIKSKGIQK
                     DNLNIIIGSDNDCELAQDCSIVTATYNVDRDLVGRISFIGPTRMDYARIYSIINYMSL
                     LINRK"
     gene            60807..61427
                     /gene="grpE"
                     /locus_tag="ACGI5H_000654"
     CDS             60807..61427
                     /gene="grpE"
                     /locus_tag="ACGI5H_000654"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430935.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000774 - adenyl-nucleotide exchange
                     factor activity [Evidence IEA];
                     GO_function: GO:0042803 - protein homodimerization
                     activity [Evidence IEA];
                     GO_function: GO:0051087 - protein-folding chaperone
                     binding [Evidence IEA];
                     GO_process: GO:0006457 - protein folding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotide exchange factor GrpE"
                     /protein_id="HFG9696383.1"
                     /translation="MDKKNEQQEVREENDTSINQESETQVELEEEVVNEECETSSEKT
                     DEKEVDDENVTDINSKLAEKKLQDELDELNDKYQRLQAEYANYRRRTQQEKETIGVFA
                     NEKIITELIPVIDSMERALDACEDKEDTMYKGISLVHKQLIDTLVKFGVEEIEAESKE
                     FDPNLHLAVMQESVDGVEANQIVMVLQKGYKLGTKVVRPSMVKVSC"
     gene            61519..63366
                     /gene="dnaK"
                     /locus_tag="ACGI5H_000655"
     CDS             61519..63366
                     /gene="dnaK"
                     /locus_tag="ACGI5H_000655"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430934.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_process: GO:0006457 - protein folding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="molecular chaperone DnaK"
                     /protein_id="HFG9696384.1"
                     /translation="MGKIIGIDLGTTNSCVAVLEGGEAQIIANSEGMRTTPSVVAFTK
                     DGERIVGEPAKRQAVTNADKTITSIKTHMGTDYKVNIDGKSYTPQEISAIILQKLKSD
                     AESYLGQTVTEAVITVPAYFTDAQRQATKDAGRIAGLDVKRIINEPTAAALAYGMDKL
                     DQEKKILVFDLGGGTFDVSILEIGDGTFEVLATAGNNRLGGDDFDQIVIDYLAEEFKK
                     AEGVDLRNDKMALQRLKEAAEKAKKELSSTMSSNINLPFITATAEGPKHLNIDLSRAK
                     FEELTRGLVEKTMEPTKTALQDAGLSTGDIDDVLLVGGSTRIPAVQEAVKKFIGKEPH
                     KGINPDECVAAGASIQAGVLAGDVKDLLLLDVTPLSLGIETMGNVMTKIIERNTTIPT
                     KKSQIFSTAADNQTAVDIHVLQGERSMAYDNTTLGRFQLTDIPPAQRGIPQIEVTFDI
                     DANGIVNVSAKDLGTGKEQKITITSNTNLSEAEIEQKIKEAEMNAEADKQKKEKIEAF
                     NQAESTIYQTEKTLNELGDKISSGEKEDIEKAIADLKAVKDNQDATAEELKKATDEVM
                     TKFQKVSQEMYQKAAQEQQAAQGAEQAQDNGPKDDNVVDADFKEVDEDK"
     gene            63577..64731
                     /gene="dnaJ"
                     /locus_tag="ACGI5H_000656"
     CDS             63577..64731
                     /gene="dnaJ"
                     /locus_tag="ACGI5H_000656"
                     /EC_number="1.8.4.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454751.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005515 - protein binding [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006457 - protein folding [Evidence IEA];
                     GO_process: GO:0009408 - response to heat [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="molecular chaperone DnaJ"
                     /protein_id="HFG9696385.1"
                     /translation="MSTKRDYYEVLGISKGAEAQEIKKAYRKLAMKYHPDRNPGDKEA
                     EEKFKEINEAYEVLSDDTKRKTYDQFGHDGLNGQGGFGGQGGFGGQGFGGFEDMFGDI
                     FGDMFGGSFGGGRARRRGPQRGADIRQSVTISFEEAAFGKKMSIKVNRSEECEECNGT
                     GAKPGTSKKTCSTCNGTGQVRTVQRTPFGNIASSRPCSACNGTGEVIESPCSKCHGTG
                     NTRKVKTIEVDIPAGIDDGQMIKLSGQGEVGEKGAPRGDLYIVVNVKSHPLFTRDGND
                     IYFEMPITFVQATLGDEIEVPTLDGKVKYSVPEGTQTGTVFRLKEKGIPRIRGNSRGD
                     QYVKVVVEIPKKLNDKQKELLREFAKECGSNVHEKKKTFGQKIEDMFKKK"
     gene            65697..66632
                     /locus_tag="ACGI5H_000657"
     CDS             65697..66632
                     /locus_tag="ACGI5H_000657"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890668.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="HFG9696386.1"
                     /translation="MYYIGVDIGGTGIQAGVVDNYGKIIFRSECKTVIEKGFEGILND
                     IKIMIYKLLEDNKLTMSDIKSIGFGVPGFINKEGLVTCVNLKWNKKAFNKELKRRFPD
                     VEIHGENDATVAALGEAKFGSMKGANVGVLYTLGTGVGGGIVINQKVFSGAHGLGSEI
                     GHQIIGENYFNCNCGNNGCVETFCSATAIIKYSQKLIEEGEKSRILDLAEGNLENVNA
                     KMVFDAYRENDLVAIKVINRFKEYLAKTFANTINSLDPEIISIGGGISKSSDIILDGI
                     EDLVRKFVLYKTEDIATITCATLGSDAGIIGAAFL"
     gene            66668..68041
                     /locus_tag="ACGI5H_000658"
     CDS             66668..68041
                     /locus_tag="ACGI5H_000658"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897645.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HFG9696387.1"
                     /translation="MGKTNARRTLFLIAIGSGTMLNPLNSSMISLALHSIQNDFHISF
                     TTVSWIVSAFYLASAIAQPVSGKIGDLIGRKVLFLSGLMLVILSASIVPLVQSFFILI
                     FIRVIQAIGTSTLYPSGVALIQNNIKERQSSALAVLTIFASTTAGLGPTLGGLLLDLG
                     GWHAIFLVNIPVVLVSICLGYFLFPKEVKEKKSIKETLKNVLSRLDIIGILLFSIAMI
                     FILLFLLSMKESFNLEQLVFGIILMCLFIWHELRTKLPFIDIKLFVSNPKLSKVYLQF
                     IILNFFNYILFFGLPSYFQDALHYSAKSTGLFMLFMSGIGIFISPLTGKWIDKSGTRF
                     PLVTSSIFMFISAVLLSVVFIHIPVIGKGIILSLAGISYGVGNVALQSSMFEESPRDS
                     IGTASGLFQTSRYLGSILATVLLGMVFEVNITSEQFQILGYVMVVLGTISFLLNFILK
                     KELRKVE"
     gene            complement(68229..>68782)
                     /locus_tag="ACGI5H_000659"
     CDS             complement(68229..>68782)
                     /locus_tag="ACGI5H_000659"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861562.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=3
                     /transl_table=11
                     /product="PucR family transcriptional regulator"
                     /protein_id="HFG9696388.1"
                     /translation="IFYNLFEDINIIQHNGFFIVNSKYNLDINVTTQNIIETETYQST
                     YIFYLGELDSKADFDFRLQLCSDLLPHIIKDNAENKFLNLFDFIRYKTLDLINEDNIL
                     NKLIDFNKIKSIDEELLYTGIKFINNDLNISKTSTSMFLHRNTLVYRLEKINEILGFD
                     LKNFENAMIFYLSVKSYFLYKKI"
BASE COUNT        27073 a         7450 c        11930 g        22329 t
ORIGIN      
        1 tgtaaaaaat atttttaaat tatcatttaa tgtaatttaa atgaattgaa gatatatgtt
       61 tattgtatgc aattgttgta tttttaggtt ttttgtgatt aattaaaaaa ttataaaaat
      121 cgtttacatg ttgattttta aaaaaaaaag atatagaatt atatagaaag taataaacaa
      181 aaattggatt tacgggagtg gaatgaaatg atgaatgtta ccttaacaga tgtgaaagag
      241 gctagagaga ccattaagaa catagtaaaa agaactgact tacttgaaag tgttaaactt
      301 agcgaaaaaa caggagcaaa tgtgttctat aaatgtgaga atcttcaaaa aacaggttct
      361 tttaaattaa gaggagcttg taacaaaata gcgagtttaa cagatgaaga aaaggcaaat
      421 ggagttatag cttcaagtgc agggaatcat gctcaaggag ttgcattggg agcaaaaatg
      481 actggtataa aatctacaat agtaatgcca gcaactgcgc ctttagcaaa agttagtgca
      541 actaaaggtt atggagcaga agtagtttta aatggtgcgg tttatgatga tgcatatgca
      601 aaagctgttg aaatacaaaa agaaacagga gcaactttct tacatccatt caatgataag
      661 tatgttatag caggacaagg aactatatct cttgaaattt tcgaacaatt agacaataaa
      721 gttgatacta tactatgccc agttggtgga ggaggaatca tctctggtgt tgctgttgca
      781 gcaaaagcat taaatcctaa tgtaaaaata gtcggtgttc aaactgcaaa tataccttca
      841 atgaaagagt caataaaaaa tggaaaagta acaacagcat ttaatgatac tacaatagct
      901 gatggtatag ctgttaaaac tccaggagat ttaacttttg aaataataaa tgaattggtt
      961 gatgaaatag tagtggttga agagacagaa attgcagaat caatattatt tatgatggaa
     1021 agtcaaaaaa tagtttcaga aggtgctggt gctgtatgta cagctgctat attaagtggt
     1081 aagtatgtac cagcaaaaga tgaaaatgta gtttgtataa tatctggtgg taatatagac
     1141 ataaatacgt tatatagaat aataggtgtt gctttagcta aagaaggaag aagatattca
     1201 tttagtacaa ttatggaaga taagccagga aactttgctg agttaactag aataataagt
     1261 gagaatggtg gaaacatttt aagtgctaat caaggtaaat tatcagcagg ggaagctcta
     1321 ggaaaacaaa gtgcggaatt tatattagag acaatagatt atgaccatat agctagaata
     1381 aagaaagcta tagaagaaaa aggttttaaa attatagaat tataataaaa agtgtatata
     1441 atatacaaga aaaatagtat aatagtgtat gaagatacat tttatgtgta ttagattaac
     1501 gaattaggag gattttaaaa tgaaacatga agtaatacat actaatgatg caccagcagc
     1561 tttaggacca tattctcaag ctataaaagc tggaaacttg ttatttgtat ctggacaagt
     1621 tcctcttgta ccagagacta tggaagtagt tgaaggagat gtacaagctc aaactgctca
     1681 atctttaaaa aatcttaaag ctatattagc tgaaagtgga gctgattttt caaatgtagt
     1741 taagactaca gtatttataa aagatatgaa tgaatttggg gctataaacg aagtttatgc
     1801 tgaatatttt ggagaaaata aaccagcaag agcttgtgta gaagttgcta gattaccaaa
     1861 agacgttaaa gttgaaatag aagtaatagc tgtattataa aaatacaata tttttaattt
     1921 gaaaaggctg aaaaactata ttctagtgat tcagcctttt tataaaaaaa taaatcacaa
     1981 taaagaacat gataaatatt gtcgaattaa aaaataaaat taaaataaat attgcaatat
     2041 ttttgagaag gttttataat gagtatataa tttgaaacgt gtaactatta aattaggcat
     2101 gagttcttgg atatttttat cctgaggatt catgcctttt ttgtattgaa attcaaaaat
     2161 ctatttaata aggaggaagt actgtgttaa attttttcaa gaaaaataaa agctataagt
     2221 tacatgcagt agtgagtggt aacagcatta atattgagaa agtaaacgat tctgtgtttt
     2281 caaaaaagtt aatgggagat ggagttgcaa ttattcctaa tagtaatgtt gttgtagccc
     2341 cttgtaatgg taaagtaact gtgcttacag aatcaaagca tgcctttggt atggtctcag
     2401 atgagggtgt tgaaatatta gtccacatag gaattgatac agttagttta cagggtgagg
     2461 ggtttaaaaa tgaagtgtct caaggagata ctgttaaaaa aggtagtcca ataataagtt
     2521 ttgaaagaga aaaaataaat tctcagggaa ttgattgtac aacaataata attgtattaa
     2581 atcatagcga attttcagaa ataaattgca tggtagaaaa tgaagttgtt gcagggcaag
     2641 atactgttat tgaaattatg aaataatagg aagggattaa ttcaatatga gagtagtaaa
     2701 aatctttaat aataatgcat tatctacagt aactaatgat aggaaagaag ctattttact
     2761 aggtcttggt ataggtttta ataaacgtcc aggagataaa gttaatgaag ataaaataga
     2821 aaagatttat tatgttcaag accacatgca aacaaaattt ttagaattat taaaaaatgt
     2881 tagtccagaa gtgatggatg cttcacaaca aattataagt cttataccag gaaatgaggg
     2941 aaaatttaat aataaaggga tattatcttt agtggaacat attagttttg caatagatag
     3001 aatgaaaaat aatgtttttt tacctaattt aatgcttttg gatataaaga tgatgtattc
     3061 aaaagagttt gaattaggag taaaagcttt agaaattata tatagagtat gtcatatcca
     3121 tttgcctgaa gatgaagcag gttacatagc tttacatttt gtcaatttac aatcaaatga
     3181 taatttggca tatgatactt taaaatttgt aaaaggtagt attgatttga ttaaagaatg
     3241 ttatggatta gaattagacg aatcgagttt aagtacatta cgttttagaa ctcatcttaa
     3301 atttcttgct caaagaattt ttaagaatga aatttgtcag gatgataaaa tgattgaaat
     3361 gtatgattat ttaattaaca atcatcctaa aaataaagaa tatttagaaa agttaaatgt
     3421 atatattgaa aaggagttta ggtataaatt agataaacct gaaaaaattt atctactact
     3481 acacctaaca aaaatcttat aagaatgaga tgaattagta atagaaatat ataattttag
     3541 ggggggataa gattgaaaga aaaactactt ggaggactgg aaacatttgc aaaggcaatg
     3601 gttcagccat taatgtattt atcgagtgca ggaatattaa tggtggtagg tgtactactt
     3661 acaaatgata tgttattagg agtacttcca ttttttaaat gggagccaat tcaaatattt
     3721 ggaagcctaa tttataactg tataatggct attattaata atcttgctgt tatatttgct
     3781 ataggtattc ctgctgcact agcaaaaaaa gagaagcaca aagcagcgtt aataggattt
     3841 atgagttata taatatacct tacagcttcc aacactatgt taacatcact aggtcaacta
     3901 gcaaaagaaa gcaagatgct tggactgata gggactggac aagctactat tttaggtatt
     3961 caagttgtag atacaagtgt atttggtgga attattttag ggtgtatagc tggatatgta
     4021 tttaatcgta caagcaacaa aacatttaaa ggagctttac agatatactc gggagcaaat
     4081 tttagtttta tatgcatgtt ctttgtatcc attttaattg gagttgtgag taactttata
     4141 tggccattag ctcaacaagg aatagcttct cttgcaaatg tcatcaaaga tacaggtaca
     4201 tttggtttat tcttatatgg ttttttagag agaatattag taccaactgg acttcatcat
     4261 ttaatctata caccatttca gttttctgat ttaggaggag tgcttaaagt tggtgcagat
     4321 acagtttcag gagcctatgc tatagttatg acagaaatga atttaccagt tgagcgtttc
     4381 tcagatagta tatactacat ggcaactgga tttacaaaga tgtttggtta tataggtata
     4441 ggagctgcct ttatttatac tgcatataag caaaataaga agaaagttaa ggcaacgatt
     4501 attccactaa taattacggc agtattagcc tctgtaacag aaccattaga ctttatgttt
     4561 gtattctgtg caccattttt attctttgta catgcagtta tagctggtct ttttatagct
     4621 ttattaaaaa tatttgatgt tactgcatta tgtggaggga acttattagt atcaattata
     4681 atgaatacta cagtaggcgt agaaaaaaca cactggccag taatgatgat attaggactt
     4741 gcacaaatta ttgtatattt tgtagtattt agttttttaa ttaagaaatt taattataaa
     4801 actccaggtc gtgaagatga gagtacagct acaggcgaag aacaatcaaa acaacttaat
     4861 ttagatgcag ggatagaaaa tataattgat gggttaggcg gaaaagaaaa tattaataca
     4921 gtagaaaatt gcatcactag attacgtgtt aatgtaaaag atgaaagtaa gattaatgaa
     4981 gatataatta atttaacgcc aaatagcggg attgtaagga aaggaaaaga tatacaaata
     5041 atttttggac ttcatgtgca tgaggtaaga cgtgcagtag aagatttttt agaagcttat
     5101 taaagatata tatttatata gcaagggtaa ataacagctt taagtgctgt ttactattta
     5161 ttaaagatac atataattta tagaggagga ataattatta tgattattac tattgttggt
     5221 ggaggaagca catttactcc aggtattgtt aagtcaattg cattaagaga aaaagagtta
     5281 gagcttgagg aaattcgctt atttgacatt gataaagaac gccaagataa agtagctgta
     5341 gttgtcaact ggatactaaa agaagatgtt aaaacagatg ttaaactaac tgtaactaat
     5401 tgtgaaaaag aagcgtatac agatgctaca tttatatttg cacaaatgcg tgttggtaaa
     5461 tatgaaatgc gtgagcagga tgaaaaaatt ccattgaaat atggttgtgt aggtcaagaa
     5521 acttgtggtt gtggagggat ggcatacgga ctgcgtacaa tacaaccaat gataaaggtt
     5581 attgatgatg tagagaaata tgctaaaaaa gattattgga tattaaatta ctctaatcct
     5641 gctgcaatcg tttctgaagc ttgtcgtaag ttaagaccaa atgcaaggat tataaatatc
     5701 tgtgatatgc caatagctat tatagatatg atagcggggt cattaaatat caatgacgtt
     5761 cataatatac gctatgatta ttttggtcta aatcattttg gctggtttac ttcaatagat
     5821 tataaacata gagacttaat ggaagagatt aaggaataca taaaagaaaa taaaatatta
     5881 ttaccaaaat cttatataga aaacttaaat aaaagtcgta gtacaggaaa tcgccatgct
     5941 gtaagtagct ggatacatgt ttgggaatct gtttatacaa tgttagaaag cttcccaaaa
     6001 tatctgccaa acacttattt aacatactat cttttaagta aagaaacagt ggaacattca
     6061 aacataaatc gtactcgtgc aaatgaggtt atggaaagcc gtgaaaaaga cttatttgaa
     6121 ggtgtgagac attacttaga aactggagaa atttctgaaa aagcatttta tgcaggttca
     6181 catggagatt ggattagtga tttggcagtt tcaattaaaa atgatacacg tagtcgtttt
     6241 ttagttataa ctgaaaatcg tggagctata ccaaacatgc catatgatgc aatggtagaa
     6301 attccagcat atattggtaa agatggtcca gaagttattg ctcgaggtcc aatacctcta
     6361 tttcaacaag gattaatgat gcaacaactt aacagtgaaa aattgatagt agaagcttat
     6421 atagaaaata gttatgaaaa agctttacaa gcattcacat taaataaaac tattccaagt
     6481 atgaatgttg ctaaagaaat tttggatgaa atgatagaag ttaataagga atactggcca
     6541 gaattaagat agtaggataa aggaaagggt ttttatttaa taattagata tgttttcaga
     6601 gtcttttatc aaaatgtatt cacaaacata tggcaatata ttaaaataaa gagtgatatt
     6661 tttagaagaa tggggtgatg caatgaacat tataaataaa attttttggg aagaagatag
     6721 gattggcatg attacaaata atttagaggc agatacacat agccactgta tgttacaact
     6781 gttcttaggg atagaagaca gcattgaaat aacagtcaat gaaaaattag ttaaatgtaa
     6841 ttgtatcata gtagataaaa atatctctca ttcattttca gcaagaaaaa aagtttatta
     6901 ctctgctatt attgaaccta catctatata tgcagaacag cttacctcaa aaatgaatga
     6961 ttttggctac tggatatgtg acaatgatgg attagagaaa ttacgtcaac aaggaacttt
     7021 tttgatagat aactctagta aagaacaata tttaagattt atggaaatgc ttaataacta
     7081 tttgaatata cctataactc tcaaacatta tgatgacaga attactgaat tgctcaattt
     7141 attacgtact tgtaattgtg ataatcatac tatttcaagt tttgcagata aagtgtccct
     7201 atcagcaagt agattatcac atctgtttaa agaacaaata gggatacctt taaaaagcta
     7261 tatcttattt catcaaatgg agtgtgcttt tagagaatta ctttctggga aaaatgttac
     7321 cgaagcttct atgactgctg gattcgatac tccatcacac tttgcaggga cagttaagcg
     7381 aatgatggga atgcctgttt ctttatcttt gaaagatagc gaatttttga aagtatatta
     7441 aatattctcg ttatataatg aagttgtact aagaaagggg ctttgttatg aataaagaat
     7501 atttagagga aacaaaaatg ttaaattata atgaaccaca acttaagctt ttggtatcat
     7561 caaagaattg gttggaatta gatgattttc ataaaataaa atctatttat gagtttgtac
     7621 agaatgatat tttatttgga tataatgctt ctgatatgtt aagcgcaaca caggtattaa
     7681 atgatggtat gggacaatgc aatacaaaag ctactctttt aatggcatta ttacgtgcag
     7741 tgaatatccc ttgtaggctt catgcttttg atgtaacaaa agattttcaa cgaggagcta
     7801 catccaaatt gatttcacta ttagcaccaa aatatattct tcatacttgg gtagaggtat
     7861 tttatcaaga taggtggatt gctcttgagg gtgtcataac tgataaaaaa tatttagaag
     7921 caattcagaa gaaatttttt aatcatggtg gaacatttaa aaagtatgca atagctacaa
     7981 atgatttgaa aaatacatct attgattggg atggtaaaga tacttttatc caaaaagaag
     8041 ctatcgtgta tgattatggt atttttccat caccagacgt atttttttct actcattcac
     8101 aacatatgtc aaaattaaaa aatttcatat atgtacatct tatcagaaaa ataatgacaa
     8161 aaaatgtatg taaggctaga aacaattata ttgataaaaa cgaatgagtg tttaagaggt
     8221 aactatatag gaaatatata gaataattaa aactgtactg gttaaaatga ataaaaagga
     8281 gttatcacag agcaaactta aattgttcat aggataactc cttttctgta ttaacttcta
     8341 ataatttgat gtctttttat aaaacatata gatacaatta aaccagtaaa tgcaagagta
     8401 gctgctattg aaaatgcaac atctattcca tgaatgttag acagcatgtt tgaactcata
     8461 tgagctttct tagtagcact tgtcattata gtaataagta tagcagaacc tatagctcca
     8521 gatatctgac ggagtgtgtt attaattgct gtggcatgag atataagttc tctatctaat
     8581 gttttaattc cccatgtagt taatggcatt aaaaccattg aaataccaat catacgaata
     8641 caatacatca atgacacatg aattaaagat gtatctctgc ctaaaaaagc gaaggataaa
     8701 gttcctaaaa acaaacatcc tgttcctaat attgatagag catgaggtcc atatttatct
     8761 aaatgacgtc ctgcaattgg attgagtaca accatcaata tagcaccagg taacattaat
     8821 gaacctgaag ataatgcaga aaatcctctt acagattgaa cgtacagagg aatcattaat
     8881 gtagcagaca tcattgaggc atatacaatc ataattaata ttgtagaaat aagaaatggt
     8941 ttatttttaa aaaccctcaa ttctaaaaaa ggttctttag attttaattg acgcaatgta
     9001 aataaaatta atgacataat tcctattaat attggtaaat atgtggcaat attagtccac
     9061 ccataattac cttgattagt aaatccaatt aataaaccac caaaacctag agatgatagt
     9121 actattgaag gtatatctaa ttttagtttt tgagtttccc caacatttct taatagaata
     9181 aatgatagta taacatctaa tatagcaata ggggaaagaa acagaaataa actatgccaa
     9241 ccaaatgaat ctactaacca tcctgataaa gttggaccta ttgctggagc aaatcctact
     9301 gtaataccaa ctaaactcat agctgcacca cgtttttcct cagggcataa atagagtata
     9361 ataacttgta aaagtggcat tagagaacca gaacccattg cctgcaacac acgagcaatc
     9421 aacatagttg aaaaattatt agaaaaaagt gcaataatac atcctataga aaagatagac
     9481 attgatgtaa taaataactt tctagtacta aatcgattta ttaaataagc tgttgtgggt
     9541 acaataatac ctgcaataag tagataaatt gttgttaacc actgaccaat atcagcagta
     9601 attttaaaat ctgacattat attaggtaat gctgttgaca atagtgtttg actgagagaa
     9661 cttataaaag caccagtcat tacaattgct attattaaat ttcctttttt attgttactt
     9721 tgggtttcca taatttataa cgtctccttt tttaattgat ttttaatgct gttcaataaa
     9781 agtacttttg gtcttaaagt gtcttctttt tctaaatatg caatcattgc atccataatt
     9841 aaagaatcat attgttgatt ttttccttcg acgtataatt tttttattgc ttctagtaat
     9901 ttaggatttt caaggagaga agtatcagtt ttgattagtt cttctatatc ttgtatcgtt
     9961 ttaaaaaata gcgatttatt atgaagggaa aagtaaactt catcttcttg tttatgtaaa
    10021 aacattgatt tttcaattaa aggatttaga ttatccatat tttctacaac taaatctaga
    10081 atttgtatag taaatttggc aataaagtat acatttattt ctcttttttg tacatgaata
    10141 atgtatataa actgatgaat tagagcatcc aataagaaaa ctaaatcaaa tataattttt
    10201 tctattttat caccatagtt atcaaataag cttagtttgt attcattcaa taagttagct
    10261 cttgattttg tttgcaattt acttgtagcc ttacgttgct cttcagaaaa gttttctctt
    10321 atataggtat ttatggtagt tctagaaaaa atatttttcc atacagcaat tatctttctg
    10381 tttaactttt ctgatgatgg aatgtcatta ttttcattta tggaatgtat aatttctaaa
    10441 aacttttcat cataataatt gattatttcg cagataaaac tttccttagt ttcaaaatgc
    10501 ttgtaaaaag tagctttaga cattttacac tcttttacaa catccgatat tgaagtattt
    10561 tgaaaacctt tttggtcaaa aattttttgt gcaatagtta taatgagcct ttgtttttct
    10621 gtcactttat tatctccttt cacgcaaaaa cgtttagtac tatatagtac ctacaagttt
    10681 tgataaatat attatacatc atttggaaaa aaaatcaata tatagactgt aatatgaaat
    10741 ttttgaaaaa tttgttgtta tttttagtcg tataaaaaag aaacttaaga gtttcttaag
    10801 aattgtttaa agaagttgca ataaattagt ggtatgatta tagtatgaaa gagaatgtct
    10861 tgaaattttt ctgtatcaaa ttccaattat ggaggtgtag tatatgaaaa agaaaatttg
    10921 tgtagcaata atttttgctc tatttatagt ttttgtagaa atgtttattg atagctctag
    10981 cgaaggaagt aaaattatga cagctgaatt aagtaaatac aggaaaggcg taaatgtatt
    11041 atcaataaac aatattatag tagcgaataa aaaatatagt ttgcccaaag attattctcc
    11101 tcaggaaagc agtgaagcga gagatgcttt ttataaaatg aataaagatg ctcaaaagtc
    11161 aggattaaat ttaaaagctt ttagtacata tagaagttat gaatatcaag atagattatt
    11221 taagtcatat gtaaaagaac atggagaaaa agaagcaaat agattttcag ctaaacctgg
    11281 agagagtgag catcaaactg gacttgcttt tgatattgga ggagatgacc agtcttgttg
    11341 ggcaaataaa aagttcaaca atacaaaaga agctaagtgg ttgtatgaaa atgcatataa
    11401 atatggtttt atacttagat atccagaagg taaagagaat ataacaggat atatgtatga
    11461 atcttggcac tatagatatg ttggaactga acatagcaaa aactttgcaa tgaataattt
    11521 gactttagaa gaatatttac atataaatta agagatggtt tgttaaaatt aggttaaaat
    11581 aaaaaataac ctagactatt agctgtgtaa agtgatataa tgtaaataca atttaagata
    11641 actactcgaa ggggagtagc ttacacgaaa gtggtaatta atcgtcaaga cagtagaaat
    11701 actcggttaa ttagcaaggg attccttgat agcaagacct tcaaaataag cattaggtat
    11761 gtttgttttg gggtcttttt ttattcaagg aatttttatt taaaaaaatt taaatttcaa
    11821 gtatacataa gagcccccaa acataaaata aatttattga agaggagggc aacaaatgtc
    11881 ttacaaaagt acttatcaag aagtaattaa aaatttagac tcaagtttat ctggtttgag
    11941 taaagaaaga gcagaagagt tgttagaaaa aaatggagct aatgaattaa aagaagcaga
    12001 taaggttcct acttataagc ttttcctaga aagttttaaa gacccattag taataattct
    12061 attgatagct gctttagtac aaatattttt aggtgaaaca gtggagtcta taataatttt
    12121 tgcagttatt attataaact ctgttctggg tgttgtacaa acaaaaaaag cagaaagttc
    12181 attagaaagt ttgaaaaatt tatctgcacc aaacgcaaag gtaataagag acaataaaaa
    12241 aatgacaatt ccagcaaaaa atctagtagt tggagatatt gtattcttag aagctggcga
    12301 ttacatacca gcagatggaa ggcttataga agcacaatct ctcaaggttg tagaagggat
    12361 gttaactgga gaatcagaac cagttttaaa gcatatagaa aaaataagtg aagatgtaag
    12421 tttaggtgac cagaaaaata tggtatttag tggtgctgta gttgtttatg gtagaggttc
    12481 ttttgtagtg actggaacag gtatgaatac tgagatgggt aaaatagctg ggcttttaga
    12541 aagtgctgaa aataaactta caccattgca acaaaaaata gaggatttta gtaaaaaact
    12601 tggtgtaggt attgtaatac ttgctctttt aatatttata attcaagtag caagaaatta
    12661 ctttatggct ggaaatggag aaatgacaca aattatttta gattcattca tgttctctgt
    12721 agcagtagca gtagcagcta taccagaagc tctatcatca atagtcacta tagtattggc
    12781 tgttggaaca aatagtatgg caaaaaaaca agccataata agaaaattac cagcagtaga
    12841 aactttaggt tcaacaagtg taatatgtac tgataaaaca ggtactctta cacaaaataa
    12901 aatgacagta gttgattatt atatgtatgg aactaataat gatgagttag ataaagaaaa
    12961 agtaaactat tcttatcatg ctaaattatt gactatggtt tctacattgt gtaatgactc
    13021 tcatataact agtgatggta aagaagttgg tgacccaaca gaagtggctt taataaatta
    13081 ttcaagtaaa aatgatttag attatgataa attaagaagt aagtatatca gaataaatga
    13141 aataccattt gactcagaca gaaagcttat gtctactgta aatagtatat atggagatta
    13201 tataatgttt acaaaaggtg ctccagatat tgtgtttagt agatgtaaat atgctttgaa
    13261 aaatggttca aaagtagata taacagatga gataatagaa gaatataaac ataaaaatga
    13321 agagttctca aatagagcac ttagagtatt agcttttgca ataaaagatg tcccagaaga
    13381 agattttata ccttcaattg atgacgaaca tgacatgaca ttggttggaa taatggcaat
    13441 gatagaccca ccaagagaag aagtaatgga tgcagtaaaa gaggcaaaga gtgctggtat
    13501 aaaaactgtt atgataactg gtgaccataa aacaacagca gcagcaattg caaaagagat
    13561 tggtataatg gaagaaggag acttggctct tactggaaaa gagcttgatg ctttgagtga
    13621 agaacaacta tatgaaaaac tagaaaatat aagtgtatat gccagagtct cgccggaaaa
    13681 taaaattcgt atagtaaaag catggcaaca taagaataat ataacagcaa tgactggtga
    13741 tggtgttaat gatgcacctg cattaaaaca agcagatata ggaatcggta tgggaagtgg
    13801 tactgatgta gcaaaagatg cttctgctat ggtattggtt gatgataact ttgcaagtat
    13861 agtaaatgct gttgaagttg gtagaacagt atacagtaat ataataaaat caattactta
    13921 tctatttgca ggaaacttag gagctatagt atccatagta tttgcagtgt ttgcaggttg
    13981 gtcaaatcca tttacagctt tacaactttt gtttataaac ttagtaaatg actctttacc
    14041 agcaattgca ttagggtttg aaaagtcaga aaaaaatata atgaataaac ctcctagaca
    14101 cccggatgaa agtatactag caggaggaac attgaaggca gttgctataa gaggttgtat
    14161 aataggtgta gttacaataa ttgcacaata tataggatta caagtatctc cagaacttgg
    14221 agtagcaatg gcattttcaa cattgatatt agctagaata atgcaaacat tacctgcacg
    14281 ttctaataat caaacagtaa taaaattagg ttttttcagc aataaatacg ttataggagc
    14341 agttttagtc tgtcttgggc tttactcttt aacactaata ccagtgctaa gaggaatatt
    14401 ctctatacca acaacgtttg gattgtacca gttggggatt tgcctagggt tagcattaat
    14461 ttcatcaata ttaatggaac ttaacaaatt aataaataga agtgaagtaa aataatcaaa
    14521 aaattaaagg gcatattgat tttaacaata tgccttttat aaatagtcta atttattcta
    14581 tattatcgat tatttggaat gcttttataa cttcaggtaa ttctttttct tcaggcattc
    14641 taaatcttat aaaattttta tcaagtccag taaaatcact tccagatata actcttattt
    14701 ttaatttagc aaactcttgt tgtaaatcta tgtccttgtt tttatgttca actgtcataa
    14761 ttgatacagt atcactagtt tcagctatat taaggttttt ccatggaatt aataattgat
    14821 tttttatatc ttttgttttt tcttttaatt cttctataaa ttgaacatca tctaataaat
    14881 ttgctgcaat actacgagat atttcagaca cttcgtaagg agtagaaatc tttttaatag
    14941 ggctaacaag ttgttctgga agaactgcat atcctgctct tagtcctgct aaaccaaatc
    15001 cttttgaaaa tgtttttaaa gcaattacat tatcataatt atttagaagc ttgacagctg
    15061 aattttcttt tggcatgtat tcaccataag cttcatctac cataactgct atatcatatt
    15121 tagctgcttc ccttactata ttttcaattg atgataaagg tataatttgt cctgtaggat
    15181 tgtttggatt gtctatgtaa attactttat attctggatt tattttttca ataaattctt
    15241 tttcattaaa cttgaaatta tcctctttct ttaaaagaac ataatcataa gttgcaccat
    15301 gcatttttat atctgtctca tattctgaga actgaggtga atatcctaaa actttatctc
    15361 ccttttcaat aaatagtcta tttaaaaggt aaataacatg tatagaacca tctgccaaac
    15421 aaattctgtc agtatctaat gctataaaat ctttccaata atcgactata ttatctttta
    15481 aagcaattga atgaggatat cctcttatca tatcaaattt taaagcatta aaagcttcta
    15541 cagctttgtt tgagtaagac acggtattta taccttcacc acagtctatc tcgaatacat
    15601 cttctgaatg tccagattct attgcataac tttttttcaa ctgcatttca atagctttgt
    15661 taatttttag tttcatactt tatcactcct tatttagtca ataataaatg ttataaaagt
    15721 tgctagattt aaaatattat gaaaatatat aatagtaaaa atgaatataa atattataat
    15781 agctcacttt atttaatatg attatatatc atatattgta aaatttctag cattataaga
    15841 ctataaattg aaaatattca gaaaaatact acaagaaacg atttattttg ctcttaaaat
    15901 aagttaaatg aatgttatta attttgtaaa ttgaaatagt ttaagtataa agttatgata
    15961 taatctaata agggtaattc tttagattat attaaggaaa tataggtata caataaaaag
    16021 ttatggagtt ggattatggg atataaatta attgtaacag atatggatgg aactttatta
    16081 ggcaataatc ataaagttac agatgaaaat aaaactgcac tacaaaaagt tataaaaagc
    16141 ggtattaatg taactttagc aacaggaaga gccttcgatt cagctaaatg caatgtagat
    16201 tttcttaaag aggacatgcc aataatagct tgtaatggtt cattaataag agagcaaaat
    16261 ggaaatataa tatattcaaa taagattgat acaagaacat gtttaaacat tttagatgta
    16321 ttagataaat acgatattta ctaccaatgt aatagtatag attctatgct ttcgaaaaaa
    16381 atagaaggac gtgaagatag attaagtgta tttttaggct ctgaaacaga agtaattgta
    16441 aaagatgatt tgagagaaga aatctttaaa aaagatatac taaaatttgt aatcatagaa
    16501 gaaaaaaatc catctatttt ggatgaaata agaaaagaat tgagaaaagt tcaaggaata
    16561 aagataacct cttcatggcc aaacaatatt gaagtcatga atgaaggtgt tgataaaggt
    16621 aatgcagtta aaattttagc tgaaaaaatg aatatagaca gagaagatat aattgcattt
    16681 ggagacaatt acaatgacat agaaatgata aagtttgctg gtcttggggt agctatggga
    16741 aatgcagaag aattgattaa acaagaagct gattatgtta cagatacaaa tcaagacagt
    16801 ggagttgcaa aggcaattta taaattccta gagttaaaag aatcacttag ctcttaaaac
    16861 agtatataat aggaaaaaat aggttgacta ttttgtagat agtaattata atacaaatag
    16921 ataaaatata aaaatttaga ttcagtgaaa aagagagtag atatagagaa aatctcagcg
    16981 aattggggga tggtgtgagc ctaatgataa cactttatat tgaaaagaac tttggagaat
    17041 actacttgaa attcagtatg gtagtaggta atctcgcctt aagagaatag agtgggtaaa
    17101 cattgtttac caactagagt ggtaacacgg aatatttcgt ctcttggtct ttttgaccaa
    17161 gagatttttt agtttcattg agttacaaga cttataatta aaatacaaaa aattaaaata
    17221 tgaggtgaaa gttatgaaat tatggggtgg acgctttaga aaagcggaaa atcaacttat
    17281 ggaagaattt aataaatctt ttggctatga ttgtgtactg tacaaaaaag atatcgaagg
    17341 aagtgtagca catgttcata tgcaagtaaa atgtggactt ttaacagaag aagaaggaaa
    17401 gtctataaca gaaggtttaa aagggatact tgaagatgta gaaaatggaa agttagtatt
    17461 ggatggagag tatgaagata tacatagttt tactgagata aatttaattc aaagaattgg
    17521 agatgttggc aagaagcttc atacagcacg tagtagaaat gaccaagttg cagttgatat
    17581 gagattgtat gctaaagaaa aagcaaatga tttggtggat ttaatatctg aatttaaagc
    17641 tactataaaa gatgttgctg acaaaaaccc agtgatgatg ccaggctata ctcatcttca
    17701 aagggcacaa gtagtgacat ttaagcatca cttaatggca tattatagta tgtttgatag
    17761 agatgagaaa agaataaaaa atgctataga aatattagat gaatcacctt taggctgtgg
    17821 agctttagca ggaactacgc atgatataga tagaagtata acttgtgaac aattaggatt
    17881 taaaaaagta gtagataatt ttatggatgg agtaagtgat agagattatt tactagagct
    17941 aatgagtgat ttttcaatta taatgatgca cttaagtaga ttaagtgaag agttgatact
    18001 ttggagttct caagaatttg gatttgttga gatagatgat ttatatacaa ctggaagtag
    18061 tataatgcct cagaagaaaa atccagatgg tgcagagctt ataagaggta agactggtag
    18121 agtatatgga aacttatttg gtctttttac agtaatgaaa ggaataccat tagcatataa
    18181 taaagacatg caagaagata aagaaggttt tttcgatagt gtacatactc ttgaaatgtg
    18241 tatacaaata atggatagaa tgatagccac actaaaggta aatgaggata aaatgaaaca
    18301 agcagtaaaa aatggttttt taaatgcaac agaagttgcg gattatttgg ttaaaaataa
    18361 tgttgctttt agagatgcac atggtatagt aggaagtatc gttatatatt gtgaagataa
    18421 taaaaaagca atagaagatt taacattaga agaattacaa aagttttcag atgcttttaa
    18481 ggaagatatt tatgatttta tcgactatga gagtatatta aataagggaa taaaaaagaa
    18541 tttaaaataa tgtatttatt tttaaaagct gtaaatttga atgttatcat ttaaatttac
    18601 agctttttat tgtgtaagat tttattatat aaaagtaaga aacttaaaag gagtagtatt
    18661 taaaataaat acaaataaaa aattattatt aaaatgataa ttaatatcaa taagtattga
    18721 caaaattatt tctaaatact attatatata atataaataa taatgaaaat caatatcaaa
    18781 taaatgggag gaaatctaat gaacttatta gtgattggtg gtcatgaaag aatggaaaaa
    18841 gattatatgg ttatggccaa gaaaaaaggt tataagacaa aggtatatac taccatgtca
    18901 tctaaattaa ataattctat aggaaaacca gatgcagttg tcatacttac atcaactgtt
    18961 tcacataaga tgtctagaac ggttgagtct caagctaaaa aacaagatat attaatcgta
    19021 aggcataaaa atagtagtaa ggtagcattt aatgaatgtc tagatatggt tgatgaatgt
    19081 ctgggaaatt gttcaaaatg taagcttaaa gacaaacaaa aacaaaaaaa tatataggta
    19141 taaaaaatac ataaacataa aattaaaagt actgagataa tagttataat tattatctca
    19201 gtacttttag atttataagg ataagtatag tataaatttt ttattataat ttccaactac
    19261 ttgttacttt ttcatatttt ttttacttct agcttttttt ctttttttct tctttatatt
    19321 tgaagctatt ataaataaaa ctaaaagcac tagaatacct gcaataatct taacaaaagt
    19381 cattaaaaca ttattttcag tcaaaaatgg aagactgcta tcaagattat tttttgcaat
    19441 taagtctata ctgttttcta gtttaccatt attatataca tttaaagtac caaccttagc
    19501 tccttttttt ataggcaaat caattttatt taactctgtt ttggtatcat aattgccttg
    19561 agattcatct ttttctaaga atatcctata actatttttt ggttcataaa tcaattcatg
    19621 ttgttttgta aacaatactt ttttagtatc tgtgtatttt tctttatcaa caatagtagc
    19681 acacttaaag ttatcaaatc cataatcaat cagaatacgt gagtctaaat ataaatcagc
    19741 attagttgaa ttaaatacag caacgataac tcttctgcca tcttttacag cactcgataa
    19801 aagacattta ccagcagcat cagtatatcc agtttttata ccatcaacta tatcatattt
    19861 tatatttata ggttgacctt tgtatgtaat cttatcatgt gatgtcaaaa acttattagt
    19921 gtttacaaag tatctctcat aaggatatgc ttttgtagct tcaaatttaa gtgacttagt
    19981 ttttacaatt tgtctaaaag tatcattatt catagcttct ctagctatga gagccatatc
    20041 atgagctgtt gtgtagtgat ttgggtctgg taatccatga ggattattaa aatgagtatt
    20101 agtagctcca attttttttg cctcagagtt catgaggtca ataaattttt gtacattgcc
    20161 accaccaaca tatctagcta atacaaaagc agcatcatta gcagaatgaa ccaaaagagc
    20221 atctagtaac tgctttacag taaaagattc cccatttttt agatacatac tagagccatc
    20281 tatttgaggt aaatctttaa tttctattac ttgatttaaa tctttaacct cctttagaac
    20341 taaacaagct gtccatactt tagttgttga agctggataa agcttagaat ttccatcctt
    20401 attatatagt attttgccag actcatagtc cattaaaact gcatgtttag caactatagc
    20461 tggttcatta tctgcaaaag agatattaga gcttcctaaa aatgaagtaa atatcaataa
    20521 acagattaat aaaagtgata aatttctttt cattgtgagc ctccaaattt taaattcatc
    20581 ttttagtata gcatatattt gtcaataatt aaaagaaagg agtgattaat atatgaaaaa
    20641 aaaggtaaaa tttatttcgt tttttgtttt atttatttta ataatatcat caataatcgt
    20701 ttataaatcg cttattttca aagatgatat ttatgttgta agtaaaaaaa atttacctaa
    20761 tgaaaaaaca catgttgtag agaatgaaat taaaggtgaa gataataatc acagtaaagt
    20821 aactaaagac atagataaaa attttcaaaa taataaaata actatataca taagtggagc
    20881 agtaaataga cctggaattg taactataga gtcagacaag agactttatg atgctgtaga
    20941 attactagga ggaacgacaa aagaagcaga tttaaatgga gtcaatctat cagtaagatt
    21001 agaagatgaa caacattaca taatacctaa aataggtgaa gcaacatctg ttacaagtaa
    21061 tgatgattcc aataaactaa atcagaagaa tgagtcaaga ggtgagccta aaaataaatc
    21121 caataaaaat atatctaacg aatcaaaagt aaatataaat gtagcgacga tagaagagtt
    21181 ggattctcta cctggggttg gagaagctac agccaataaa attttacaac acagagaaga
    21241 aaatggacag tttagttcaa ttgaggaaat aaaaaatgta aatggtattg gagataaaaa
    21301 gtatgaaaat ataaaagatt taatttgtgt agactaaaat ataatacaaa acttacatat
    21361 agatatgtta ttataaatat gtatgtatat gtgtgtacat gtggaaattt agtaaaggag
    21421 gcacttttat gaaaaaagaa caaaaaaaac ttacagagat gacaacagca ggtggttgag
    21481 ccgctaaaat agggccagag gttctggcat cagttttatc tcaattgcct aaaaatgata
    21541 atatagaaaa tttattagta ggactagata cagcagatga tgctgcagtt tataaattaa
    21601 atgatgatat ggcacttatc caaactttag acttctttac accaatggta gatgacccat
    21661 acgtatttgg tcaaattgct gcatcaaatt cactatcaga tgtatatgct atgggaggca
    21721 aacctttggt tgctatgaat attgtttgtt ttccatcatg ccatgatatg gatgtacttg
    21781 cagaaatatt aaaaggtggg tttgataaag tgaaagaaag tggagcactt ttggttggag
    21841 ggcatactgt agatgacaaa gagcctaaat atggtctttc agtttctggg attgtaagtc
    21901 caaataaagt tttatcaaat gctactgcaa aacctggtga taagttaatt ataacaaaac
    21961 caattggagt gggtgtatta aatacagcca tgaaagaagg tatggtagaa caacatatag
    22021 cagataaagt aatagaaata atgatacatt taaataaata tgcagcaatg agttttgaga
    22081 aatttgatgt aaattcggtt acagatataa ctggttttgg tctacttggt catactttag
    22141 aaatggccaa agcttctgaa gtaagtattg aaattgaatc aaaacatgta ccaattattg
    22201 aaggtgcaat agaaatggca caaatgggaa ttatacctgc tggtatgtat aaaaatatgc
    22261 attatgtatc taaagatgta gaagttgtag gaaatataga agttgcagtt caagatattt
    22321 tatacgaccc acaaacatca ggagggttgt taatttcagt aaaagaagaa cttgcagagg
    22381 agcttgtaaa agatatgaaa ttaaatggag caatagaagc taaaattata ggttctgtag
    22441 ttccaaaagg ggaaaaatat attacagttt tataaaatat tatagagaaa gagtgattgt
    22501 tttgagcaaa agagaattgt ttgcaatgtt gccttcagtt gatgaagtat taagtgataa
    22561 tagaattgta gaaataataa atgaatatcc tagaagttta gttttagaat ctgtgagaga
    22621 agtaatagat ttaaaaagac aatttatatt aagattaaaa gaagatgcat caaactctgt
    22681 aacaatagag tttggtgaaa taatagaatc tgcaatagag agagttaagt taaattactc
    22741 attatcttta aaaaaagtta taaatgcaac tggtacagtt attcatacaa atttaggaag
    22801 gtctttactt agtgaagata taaaagatga attatggtgt gctgcttcaa ggtattcaaa
    22861 cttagaatac gatttggata atggagaaag aggttcaaga tactctcatt taactagtac
    22921 aataaaaaga cttactggag cagaagatgt actagttgta aataataatg cagcggcagt
    22981 acttcttgta cttagcacaa tggctaaagg aggagaagca attgtatctc gtggagaatt
    23041 agttgaagta ggtggttcat ttaggattcc aagtataatg gctcttagtg gtgcagaatt
    23101 agttgaagtt ggttcaacta ataaaactca tttgaaagat tacaaggagg ccattacaga
    23161 agatacaaat gtattgatga aggttcatac aagtaattat agaataatgg gattcacaga
    23221 gagtgtttct atagaagaat tggttaattt aggtaaaaaa tataaactac ctgtaataga
    23281 agacttagga agtggagttt ttatagattt atcaaaatat ggtttatctt atgaaccaac
    23341 tgtattggat tctattcgac aaggtgcaga tgtagtaact tttagtggag ataagatgct
    23401 tggaggtccg caagcaggta ttatagttgg gaaaaaagag tatatagaaa aaatgaagaa
    23461 aaatcaactt actagagcac ttagagttga taagcttaca atatgtgctc ttgaagcaac
    23521 attgagaatg tatttagatg agacaaaagc tatagaaaat atacctactt taaaaatgtt
    23581 gacatataaa attgaagaat tagaagtaaa agcaaataaa ctatttgaaa aaataactgc
    23641 tttaaactta aatgcaaaca taaatataga agatggattt tcacaggtgg gaggagggtc
    23701 tatgcctctt gaaactataa gtacaaaggt aatatcaata actcctgaac atatgaatgt
    23761 ttcatcttta gaaaaaaaac taagacttag tgaagcacat ataatagcca gagtgtatga
    23821 taataaatat gtactagatg taagaactat atttgatgat gaatttgatg taatagttga
    23881 ggaattgaga aaagcattta attaaataaa tttgagttaa taaatattaa atttagaagt
    23941 ataagtatga agttttgatt aaaaaatagc tacacacact tgtgacttta gtcatagcag
    24001 gtttagaggg ggcaaaaaat gaaaaatgta gtaattggaa cagcaggtca tattgaccac
    24061 ggaaaaacta ctcttataaa agcattgact ggaagagaga ctgatacgtt agatgaagaa
    24121 aaaaagagag gtatttcaat aaacttagga tttacttatt ttgatttacc aaacaataga
    24181 agagctggaa ttgttgatgt cccaggacac gaaaaattta taaaaaacat gttagctgga
    24241 gcatcaggaa ttgatatagt tttacttgtt gtagcagcag atgaaggggt tatgccacag
    24301 acagttgagc atttagatat tctaagcttt ttaaatatca aaaatggaat agtggttcta
    24361 actaagtctg atactgtaga tgatgaattt agagagctag taaaagaaga tatttgtgaa
    24421 aaaataaaag gaacttttct tgaagatgct gaaataattg aagttgattc tatatctaaa
    24481 agaggtatag acactcttat tgaaaaaata gataaaatga gtgatgatat agaagataaa
    24541 aatgaaaact ctccagcaag acttaatata gacagagtat tttcaataaa agggtttggt
    24601 actgtaataa caggcacttt aatagaagga aagataagta tagaagatga tttggttata
    24661 tatccacagg tattaaaaac aaaaataaga agtatacaag ttcatggaga aaataaagat
    24721 acagcttatg caggtcaaag aacagcaatc aatatatcaa atgtaaaagt ggatgatata
    24781 aaaagaggag atgttttagc tgcaccaaac tcattggagg aatcaatgat gttagatgta
    24841 aaattatcat tggtaaatca tttagataaa ggattaaagc actgggatag attaagattg
    24901 tatcatggaa ctagagagat actttgtaga gcagttccac tagataaaga attaattgaa
    24961 agtggagaaa gtggctatgt tcagttgaga cttgaagaaa gcatagtatc taagaaaggt
    25021 gatacgtttg tagtgagacg ttattctcca atggaaacta taggtggagg tgtaataatt
    25081 gacccatctc ctaaaaaaca taagaaattt gatgaaaaag ttatagaagc attaaaaata
    25141 aaagaaaaag gcgaactaaa agatataata gaagagtact taaaaaggaa tttaaaaaat
    25201 tatccaaata taaaagaaat aatgagctat agtggtgctc atgaagaaga tgtaaaaaga
    25261 gcgcttgaaa cacttatatc agaagataaa gtatttatta taggaaatat gtatatgcat
    25321 ataaatcaat acaataaatt aaaagaaaat acaataaagc ttttaagtga gtaccataag
    25381 aagtataggc ttagaaaagg gatactaaaa gaagaagtaa ggtctaagat agagagtaat
    25441 tttaagacta gggagatgga tattttatta gaaaaattgt ctacagaaaa tgctataaaa
    25501 atagaaaata atatagtatc tctattagat tttgaggtta ttttaaatga taagcaaaaa
    25561 gaaatagcaa aaaaaataga aaaaagatta aaatcatgtg gagtttcttc tatactgaca
    25621 atagatgaag tttctgaagg aaatcataac tatgctgaag tattggagtc aatgataggt
    25681 aataaagtag agaaattaga tgatttgtat ataatggaca aagatattta tgaaaatgca
    25741 aagaacattt tgataaatta tataaaagaa aataaagaaa taacattagg agaatacaga
    25801 gatttgattg attctagcag aaagaattgc atgattatat tggaaaactt cgatagaaac
    25861 aaaataacta aaagagtaga aaacaaaaga attttgtttt agcagaaaat gtctgttttt
    25921 gctttaaggt ataaagaagg aattataatg tcgagtatcg tataattaat tagtataaaa
    25981 tattaattaa gaggaagtgt aaagtattga agaatataat acctgatgta aaaccagata
    26041 taaaagaaag agaagacatg agccttttat ttataataat gggctcagta cttttattat
    26101 ttattataaa agatatagag aaatatgaaa ctttattaca tgccatatat acgatatttt
    26161 tagtagctac aggagtaatt atatttaata ctacaaaatt taaagtagat tcattttcta
    26221 catttttagg attaattttt atagctactg gagtattgga gtgtatatat ttatttaatt
    26281 ccttggggat taaaactaag tctataatgg agattaacat cacaatatca gcaataacag
    26341 atttatttcc tatactgggt gtatacttaa gttttaaatt tgttaaggat aacaaacaaa
    26401 tttattcaag tgtaatttta tttatagcaa ctgctacatt aacaataaca tctttattca
    26461 taatatcagg aatttgtgac tatctgggaa atggtaaatc acaatatgct ttaggagtta
    26521 taatatctat attcataata attatttcta tcattagtgg aattgaatta aattcaagtt
    26581 caaataaagg taaatgggaa tatgatgaaa aaaagatttt taacagaata atagtaataa
    26641 taatcttatc aagagttcca aatctattgc atatagttat tgataataga aatgtagaga
    26701 ggatattatc acaaataata ataaatgtag ccttatatta tttatataat tacatagtat
    26761 ctaagaatat taagaaaaca gcactggaat tgcatgatac gaatgaagaa ttaacaaaaa
    26821 aaacggaaag tttaaaagaa aagaataaaa aattaatcta tgagacagaa aagatagagg
    26881 aacttaaggg aatacttatg aaaagagaat ctaggctaca atctacatta gatgtagcag
    26941 taaatagcat agtagtattt agcaaagatg gagaaattac atatgcaaat aagagcttta
    27001 gaaatacttt tggagactat aaagaacaag ataaattgac tgataaaata aaaaacttca
    27061 atgatttgat agaaagcatt cattatgtgt ttgttcatga gaagaatgca gagaaactta
    27121 ttagtacaag cgataataaa gtttatcaag ctatatttgc acctttaatt attgcttcac
    27181 aaacagaagg agtattgtgt gtactagaag ataagactaa gaaaaaggag tacgaacgca
    27241 aacttattga agcaaataag agaagtaaag attttttaga aagtattgga gatggcatag
    27301 tagtgcttga aggtaataac aaaatatatg ttaataatgc atgtagggaa atttttaaaa
    27361 ataatttaga gagtattgat ttttcattag tatgtaaaag tgaagaaagt atagaaaaaa
    27421 gatatgtaat agatggtgaa gtaaagtatg tagagatgag tttttctcag tatactaatg
    27481 ctggtactaa taaaactatt attgtaatac gtgatacaac ctctcgaaaa atatctcaaa
    27541 taaaacttga ggaaagtcaa tcatcatatt caagatttat agatatatta cctgatggca
    27601 tatgcttatt aaaagaagat ttaagtataa actatgcaaa taagtcgttt ttagatatgc
    27661 tagcttttac aaacatagat gatataaaag attctaatat taaactatta atgaatgcga
    27721 atactgaaga aaaaatgaaa tttacggata atatggctaa agttttaaat gaaaatagaa
    27781 gtatactttt actggaacat gaattgataa atagttatga tgatatagta gaagtagaat
    27841 taagtgcatt accttttgct atatacaata ctagatacat aatgcttatt ataaaagatt
    27901 tagtacataa gaaatattcc gagcaagcag aaaaagaact gcttgaaaga tttaaaacag
    27961 ataaaatcaa aacggagttt tttgcaaata tgtctcatga actaaaaact ccactaaatg
    28021 ttatatctag ttcaaatcaa ctggtagatt ctttctatag aaatgaaaag ataaaagatt
    28081 acaataacaa tattaaatct catgtggatt tagttagaca aagttcttat aggcttcaaa
    28141 gattaataaa taacattata gatttaacaa agatggagtc tgggttctat acactaaaac
    28201 ttgcgaaata caatattgta tctgtaatag aagacttatt tatgaatata gaagagtatg
    28261 cacttagaaa agacataaaa attctttttg atacagacct tgaagaaatt aatgtttata
    28321 tagacaaggt tgaaattgag agaattatgt tgaatctatt gtcaaactgt attaagttta
    28381 ctgataatgg aggctggata tatgtaagta ttcattataa aatagataaa gtaatcataa
    28441 gtgtaaaaga cactggagtt ggaataccac aagataaatt agagttgatt tttgaagaat
    28501 tttcacaagt tgataagact ttatccagaa atactgaagg aagtggaata gggcttgcta
    28561 tagttaagaa tctagtaagt cttcatggtg gagatataga agtagtaagt gaagtgaata
    28621 aaggcacaga gttcttaatt tcacttccaa tgaagggatt tagtagtgaa cattacacag
    28681 aagataagag aatatataat attcaagaaa aaataaaaat agaattttct gatatatatt
    28741 attaaaaatg attatgagca aaaataaaat aaaaatacta tttgtttaaa tatttaagtt
    28801 gtaagaaata ggctatcata aggtaaatta ttatgatagc ctatttttag ctaggtttta
    28861 tatctatatg tgagaacata taatctctaa attaccttca aaactaaaat ctccaaagtc
    28921 gtttggcagt ataaaatgca tacccttttt taaattatat tctacagaat tgtgtataag
    28981 ttttccattt ccatccaaca cactgtataa agaaaaaggt gtattgtgtg taaaattaca
    29041 ttttccaaaa acatctaatt tataaacact aaaaaattcg tttgacacaa atgttgtgca
    29101 tttaaagtct gatgttgata cgattttata gtcagtatcg aaatttatat gaggaacatt
    29161 cgtaacatct attgattttt gaacatgaag ttcacgctta ttacctgaat tgtcagttct
    29221 atcataatca tagactctat aagtagtatc tgagttttgt tgagtttcta aaatcaatgt
    29281 tcctttgcat atagcatgta tagtgccact tggaacatag aaaaagtctc ccttttttat
    29341 attaaccttt ctaagtagtt tgtcccattc attattattt accatattta caaattcttt
    29401 atgagatttt gcattatgac ctattataat ttctgcatca tcagaacaat ctattacata
    29461 ccaacactct gtcttaccta actctccatt ttcatttttt ttagcatatt catcatttgg
    29521 atgaacttga actgataaat tatcatttgc atccaatatt tttgtaagta aaggaaactt
    29581 atcaccaggt gtgtttccaa ataattctct atttttattc cacaattcag atagtttttt
    29641 acctttatat tttccatttt ctattaagca atctccattt ttatgagagc ttatagccca
    29701 acattcacca gttgttggcg aatctatttc ataattaaat ttatctttaa gtgcagtacc
    29761 accccatatt ctatccataa aaataggttt taaaaataat ggttccataa tcctgttcct
    29821 cctatgatat taaatttatc ctacaaataa ttatatataa atagattata aaatcaatag
    29881 taaaaaagtt ttgtcccttg aaatgacata aagtataagg agttattaaa taagataaac
    29941 tatgatatat aatataaagt tctaaattgg agtgataatt atggagttgt ttaaggcaga
    30001 aagcaaaaaa tataaaaaag aatttttaaa attattggag caatgggtta gtataccttc
    30061 attttatgat agaaaaactg tatctaaaga catgcctttt ggaaaaggag tatatgatgc
    30121 attaaactgg tttgaaaatc taggtagaga aaacaatttc aaagtaaaaa atatagataa
    30181 tcatgctgtt caaattgaat atggaaatgg taaagagtat gtagatatat ttggacattg
    30241 tgatgttgta aatccaggtg aaggatggga tagtgaacca tttaaactaa atattatagg
    30301 tgataaatta gttgctagag gtgtatctga taataaaggg cctatgatag tgaatttttt
    30361 agcactaaaa atgataaagg atttagatat taatttaaaa agaaaggtta gattaatagc
    30421 tgggggaaat gaagagagtg gatttaaatg tataaagcat tattatagca aagagccata
    30481 tggtgtatgt ggatttactc cagatgctaa atttcctgta ttaaatggag aaaaaggtgg
    30541 agcaataata aagttaattt caaatataga cgataaatct ttatatataa gtggtggaat
    30601 agagtttaat acaataccag ataaagttta tataaagaat gtagaaaaat tgggtaaaga
    30661 taatatatgt tttgatatta acaatatatc gataaattat gataatggca attatattgt
    30721 gtatggaaaa ggtggtcatt catctaaacc cgaaaaatca ataaatccta tattagctac
    30781 aattaaactt ttgtcagaaa atattgatga aaaatggaca aaagatttat ataagttgat
    30841 aaatcaagat aatataaatg gaaacttatt tggtttaaat attgagggga aatgtggaat
    30901 tttatcaatg gtgccaacaa taataaatat agtagatgga aaattagaag tagttttaag
    30961 cgttagatat ccagaaatat taaccattga agatataata aaaaaattta atttgtatat
    31021 ggagcaaaat aatattaata aatttgagct tattggggaa aatttaaagc aagcaaatta
    31081 tatagataga aattcaaaac ttgtaagaag tttgcatgat atatatataa agtattctgg
    31141 agatttaaaa aatgatgtta gagtaactag tgcaggaagt tatgcttctg aaatgaataa
    31201 ttcagtaata tttggttgtg aatttcctga tggtagcttt ggcaatgtcc atagtgcgaa
    31261 tgaatttgct agcttagata gatttataac tgcaataggt atatatgcag aggcaataat
    31321 tacattatgt aataaaatat aaatacaaaa tgtcccttat atagacatat tatatataca
    31381 attaaaattt tacttgatat ataattgaaa tcaaagagaa ggtgatacaa tgataactaa
    31441 gaaacatgca ataatagtaa agagtttaag caataaagat ggatatatga catcaaacga
    31501 attagctatc aaattggatg tgtctactaa aactattaaa agatatatag cagatttaaa
    31561 tagtgtttta agcaaatatg atttggtaat agcttcttct agaggtatag gatacaagtt
    31621 aagcggttct aaaaacaata tagccagagc tgttaaagaa gcaaataaat atattgatgg
    31681 ttttttagat gactctgaag agtcaagaat gtcaaatata atatgtatgc ttattaatag
    31741 aaattatatg agtatagaag caatggcaga agaattaaat ctaagtatag ccgctataaa
    31801 taaattgtct agtaagctta aaagaaaact tgaaaagtat gacttagtta taaaatctaa
    31861 accttactat ggaagctata tacatggtga agaaattaat ataaggcaat taattactga
    31921 ctatgcaata aaattagatg aaaaaagtaa agtgaaggtg tttttagatg acattagtga
    31981 aaacgatata cactgtatag aaagtatttt agaaaagcac ttaagagaaa aagatacaat
    32041 aatttcagat aaagatttta atcttttgct ttcaaaaata atcgtttctg tatttaggag
    32101 taagagaggt catagtaaca atataaactt aatggataca agttatagat ttcataacta
    32161 ctactttata gaaaatctaa tgaaagaaat atctgataaa attggattta aacttattga
    32221 agatgaagta atttatattt caaattattc tggtgtaata gcctataaag gtacacaagg
    32281 aagaaaaaac acaagtgaaa ttgaggaacg aataagtagt gttataagta gtgcacttca
    32341 agatatattc cttatttcag gtagtgatta tacaaaagat gatgagttta tggttgcaat
    32401 ctctgaccat ataaagagat ttttaaatag agctagagct aatgtaaaat caaataatcc
    32461 tttacttcat caaataaaag agaagtttcc tatagctttt aatttagccg tgtttttatc
    32521 aaataaacta gaaactgagt ttaatttaaa acttgatgaa gatgagcttg gatatatagc
    32581 tatccacttt gctgcttcaa atgaaagaat gaaaaaaaat actagtaaga aaatttgtat
    32641 agtttgtcat tatgggatag gaacaggaca acttatttct gaaaagctaa aacagaatat
    32701 aagtgattta agtgttgtag gtgtttatcc agttagatat ctcgatatgg ctataagtca
    32761 agatgttgat ttgatagtat ctaccgttga attaaaagga tatgaaaaac ctgtcttata
    32821 tatagaaaat atatttgatg atagcttaat tgaaaacgta aacaaagcct tttatgaaaa
    32881 ggaagaaaga agaaagataa taagcaacat gtttgatgaa aaagcttttt tcagtataaa
    32941 ggctaatact aaagaagagg tcataatttc actttcaaat aaactaaaag aaagagattt
    33001 tatagaggaa agttctataa aaagtataat agatagagaa aatatttcat caactgaaat
    33061 aggaaatcta gtagcaatac cccacacaat agtgaaggga gataaaaaat ctataatagg
    33121 agttggaata cttgaaaatc caataatttg ggataagcaa gaggttcagc tagtatttat
    33181 ggtatttttt aatactaaag aaaaacataa tttctcgata tttaaatacc tttataattt
    33241 tataaaagat gaaggcggag taagaggaat tattaaaata tgtgacttta ataaattaat
    33301 ggcactgata ggtaattaag gaggaaatta ataatgggaa caaacatatt taacaaagaa
    33361 tatgtatttt taaatgttga tgctaagtca aaggttgaag ttttaaaatt tatatcaaaa
    33421 aaagctaaag acttaaactt ggcagaagat gagagcttag tatatgaagg tttaatggct
    33481 agagaagaac aatttactac aaatttagga gaatctatag caatacctca cactaaaaat
    33541 gatgcaattg aaaatccagc agtagtagta ttgaagttta atgaagatgt tgtttggaat
    33601 gaaggtgagg ataaggttaa attagcaata agcttactta tgccaggaaa aagtaaagag
    33661 aatattcatc ttaaattatt atcatctctt tcaagaaaat taataaataa agaatttaaa
    33721 gattctcttt taaaaagtga taatgttgaa gaaatatcta acttaataaa tgaagcttta
    33781 ggtttataat taaacactaa ggttataaaa taaaaaaata attaactaaa aataggagga
    33841 atttgaaatg aataaaaaat tagtagcatt atgtgcttgt ccaatgggac tagctcacac
    33901 tttcatggca gcagaagcaa tagagcaagc agcaaaggca ttaggttatg aagcaaaagt
    33961 tgaaactcaa ggtgctgatg gtgtacaaaa tgagttaaca agagatgata tattaggagc
    34021 aactatgata atacatgcag tagcaataac accagaaggt atggaaagat ttgatggttg
    34081 tgaagtttat gaagttgaat tacaagaagc tataaaaaat gcagaaggtg ttataaaaga
    34141 aatagaagaa gatttaggaa tataataaat ttattgtgga ggaaatagaa tggcaattaa
    34201 gaaaaaagtt ataaacagtt caggtgcttc tacaacagga ggaaataatg taggaaaatc
    34261 tactccatct agtccaactc aatcaaaggg aaatggaaaa tggaaagaaa taagtaaaca
    34321 tataatgaca ggtatatcat atatgatacc agttttagta atgggtggac ttataggggc
    34381 cttatctcaa ttaataccat atgctatatt aggacttgac ccatctgtag gtatagttga
    34441 tgctatgaac tcaggagaat ttacagggtt caagcttagt cttttaaata tagcacaatt
    34501 aatgtcaaat ttcggattta ctttgtttgg atttgcgata ccactgtttg cagcattttg
    34561 tgcaaactct ataggtggaa aaacagcttt aattgcagga tttataggtg gatatatagc
    34621 taataaacct gtaggtgtac cacaattcgt tgatggacaa tggactgaag ttgttccagt
    34681 tgcatcagga tttttaggtg caatactaat agcatttata ataggatatt ttgtaaaatg
    34741 gttaaataaa tctataaaag tttctcataa ctggttagct tttaaaacaa catttttaat
    34801 accattaata gcgtcattag cttgtatggt attgatgata tttataataa ctccatttgg
    34861 tggattaatt aatgaaagta tgaaaaactt cttaacagca gcaggagcag ctggagaata
    34921 tgtatatgca acagctttgg cagcagctac agcattcgac ttaggaggac caataaataa
    34981 agcagcagga ttcgttgcac ttggtttaac tacagagaat gtacttccaa taacagcaag
    35041 aacaatagct atagttgttc ctccaattgg attagggtta acaacattat tagataaaag
    35101 attagtagga agaagagtat atgatagaca attctatcaa gcaggaaaaa cttctatatt
    35161 cttatcattt atgggtatat ctgaaggagc aataccattt gcacttgaga gaccaggttt
    35221 tgttatacct ttaaacatag ttggaagtgt aataggagct attacaggta taattctagg
    35281 agcaattcaa tggttcccag agtcagctat atgggcatgg cctctagtag ataacttatt
    35341 tggatatata ataggtatag cagttggtgc tatattcata gcagtaggaa atatattcta
    35401 tagaaataaa ttaataaaag atggtaaact tgttgtagat tatatcgact agtatttaat
    35461 ttttactatc tataaataac tttggctggt aatatggttt taatcaatat taccagcctt
    35521 acctatatga ttaattaaag gcggtggaga taagatatgg ataagataga aaaagtaaga
    35581 gagtatttta gagaatatga tatagatgga tttcttataa atagtcctac aaacaagttt
    35641 tatgttggaa atttatttag ctcttcaggt tatgttttta taacgaaaga atcacaatat
    35701 ataatagtag attttagata ttttgaagaa attaaaagaa aatctagttt gtttaatgta
    35761 gtattaatgg acaaaactag aactcatttt gatataatta atgatatttg tagagagcag
    35821 aatataaagg aaattggatt tgagggaaat gaagtatctt ttgatttata tagaagtatg
    35881 agtaataagt taagtgcaac cttaaaatca gttgatttat ctacattaag ggaaacaaaa
    35941 aatgaagacg aaataaaata tataaaaaaa gcttgtgaaa tagttgatgc tacattttat
    36001 catatagtag actttataaa ggttggtatg actgaaaagc aagttgaaaa tgaaattgtt
    36061 agaattataa aagatttagg tggtcaaaaa gaatctttcg atacaatagt tgcatctggg
    36121 cttagaggag cattacctca tggaaaagca agtgaaaaag ttatagagta tggagatttt
    36181 gttacctttg actttggtgc taagtataat aattattgtt cagatattac cagaaccatt
    36241 tgtatgggta ctataaataa agagttagaa gaaatatata atatagtaag aaaagctaat
    36301 gaagagtgta taagggtttt aagaccggga atgactactg gagagataga taaagttgca
    36361 agagacataa ttggttcata tggatatgct ggtaattttg gtcataatct gggtcatggt
    36421 gtaggaatta tggttcatga atatcctgca ttagctcctg aatcaaatga agtattaaaa
    36481 gaaggaatga ttgtaactat agagcctggt atatatgttc caagtcttgg aggcgtaaga
    36541 atagaagatg atgtacttat aacacaagat ggatgtatga gattgactac atctactaag
    36601 gatttaatag ttgtaagcta aaaataaatt agataaatat tttataacaa taagaaaaga
    36661 agaggtaaat ttaaatgtat aattttgatg ataaaccaga tagagtaagt gaaaagtgta
    36721 gaaaatggga tttaaatatt ataagagata aatttggaga tattagagaa gattttatac
    36781 caatgtggat tgctgatatg gattttaaaa taccaacaga aatagaaaac aaatttattg
    36841 aagctgtaag aagaggtgta tttggatata catactgtta tgatgaattt tatgattcag
    36901 ttattggttg gcaaaaaaat atgcatgagg taaatgtaga aaaagaatgg attacattaa
    36961 cttatggaac tgtatcaaca cttcattatg tagtacaagc tttttgtaag aaaggtgata
    37021 gtataatatt aaatacacca gtttatgacc cctttgaatc atcagcaaaa aaacaaggtg
    37081 taaatgtaat ttgtaataca ttagatgttg taaatgatag atattatata aattttgata
    37141 aattagaagt tcaaattaaa gaaaataagc ctaaattaat gatgttttgt acaccacata
    37201 atccatctgg aaggatatgg acaattgaag aaatgacaag ggtagcaact atatgtaaag
    37261 aaaataatgt tattttggtt gcagatgaag tacatgcaga gcatattcat tatggtacat
    37321 ttaattcaat acttaagatt ggaaaagagc ttttagaaaa tgttattcta ttgacatcac
    37381 caaataaagg atttaatctt ggtggattaa agacttctta ttcaatagtt ataaataagg
    37441 atataaggga caaatttaga aataaattaa agcaaaattc tataacttct ccaaatgtgt
    37501 ttggaataat aggattgata accgcttata atgaatgtca tgagtggtta agtggtgtaa
    37561 atgaatatat aaaatcaaat tatgaacttt tagaaacttg ggtaaataaa tataataaga
    37621 taaaattgat gaaaatggaa tcatcttact tagcttggat ggatataagt ggattaggta
    37681 ttagtgcaag tgagtttaca gataaattgg ctatagatac aggagtatta ttagaagatg
    37741 ggagtcattt tgtaaaagat ggtgagaagt atgttagaat aaatttagga actcaaaagg
    37801 aaaatgtaat tgaagcttta aatagaatgg atttattttt aaagtcttta taaaaatttg
    37861 gttgaattag tattttatat aaatttaaac tattaatatg gtatatacat aagtagaatt
    37921 tgttttagat tacttaagta tataccatat tttatataaa aattaaattt gcattagtca
    37981 tgtgataact atttaaattc atatgtattt tgtatgtata atagatataa ttattattta
    38041 aacttattgt ttatttaatt tttcaataga aaaagattta tctgtaagtt taaaattatc
    38101 ttttataccc ttagttaagt atactttctt atccttagtt atgaatatag catctacatt
    38161 atcaatttta ttaattaaat tcataccttt ttcaagacca agaccaaatg tagaagtgga
    38221 taaggcatca caattaatag atttatcaga gattattgta acactactta aattgttttc
    38281 aaaaggatac cctgtaaatg gatttaacat atgatgatat atttttccgt ttttttcgat
    38341 aaatctttca taaattccag aagtaacaac agacttattt gtagtttcta tgtttcctat
    38401 ggattcacca tttttactag ttgggtcttg aatacctatt ttaaaaggtt tatcattttt
    38461 accattttct aaagtaaata tatttcctcc taagtttact aaaccttttt ttacgtcctc
    38521 tgattttaaa taggctacaa ttttatcagc agcatatcct ttagctatgg cacctaaatc
    38581 aattttcata ttttctttgg ttaattttat agatttattt ttttcatcca atatgatgtt
    38641 cttataatca ataagaggca gaagtttttg tatctcagaa tcacttggaa ctttagcttt
    38701 atctgttcca atagcccata aatttgataa tggaccaatt gttatgtcaa aatatccatc
    38761 tgataatttg gaatattgta tagcttcttt tacgacgaaa aatgtatcat cagaaactct
    38821 gacaaatttt ttaccagcat tatcatttat tttagaaaca tcacttcctg gtatatgagt
    38881 gctcattttg ttgtcaatat atcttaaaat tgaatcacat tcatttaaga ttttatcact
    38941 tttggattct tttacattaa atacagtaac ttcgtttact gtaccaaggt agtagctagt
    39001 tttactatat ttagtattct ggcttgaact cctaaaaaat gaaaataaaa ttaatgctaa
    39061 aatcaatatc acaaaaataa atgtgatttt tttcttattc atggtatatt cctcctatga
    39121 aattgtgtta ttattttatt ataacataat ttcataggag gacaaaaaat gaagaaaaaa
    39181 gacattcttc ttattttagg cattttggtt gttattacag catgttatgg gataataaat
    39241 gttataaatt ctaaaaatgc tggaaatatt gagatttatg tagataataa attgtataaa
    39301 actgtttcaa taaatgccaa agaagaattt aaaatagaga atagaggggg gtataacata
    39361 gtaaagattc atgataaagg ggttgagata gtagatgctt catgtcctga taaggtttgc
    39421 gtacatactg gatttataaa caagccaagt caaagcatag tttgtatacc taatagagtg
    39481 agcataaaaa taaatacaaa tgaaaagaat gataatcaag aagatataat ttctaaataa
    39541 aataataaaa ataattgaaa ggaattggtg ataattatgg ttaacttagg aaacgattgg
    39601 gatgaattat tgaaagaaga atttgaaaaa gattactact taaacttaag aaaatttctt
    39661 atagaagaat ataaaacacg ccaaattttc ccaaatatgc acaatatata tgaagcttta
    39721 aaacacactt catacaaaga cacaaaagtc ttaatattag gacaagaccc ttatcatgga
    39781 gataatcaag ctcatggttt agctttttca gttcaaccac aagtgaaaac tccaccatct
    39841 ttattaaata tgtataaaga attaaaagat gatttaggtt gttttatacc taataatgga
    39901 tatttaatgc cttgggcaga ccaaggagtg ttacttttaa atactgctct tactgttaga
    39961 gcgcatgaag ctaattctca taagaacaaa ggatgggaaa ttttcactga tagagtaata
    40021 tctattttaa gtgagcgtga agacccagtt atttttgtac tatggggaag taatgcacgt
    40081 aaaaaagtag agttgattga tacaagtaaa cattatattt tggaagcacc tcatccaagc
    40141 ccattgtcag caagtaaagg cttttttgga tgtaaacact tctctaagat aaatgaaatt
    40201 ttgaaaaagc taggaaaaga acctattaat tggcagatag aaaatatata aaagtaaaag
    40261 gtaacaaaat gataacaaaa caacaataaa caatgacatt gttgtaacta atagaaatat
    40321 gcttaaatag ttgaaaatac tatgtatgca tatttctatt tttttgtcaa gttgacaact
    40381 cttgaaaaaa tagttacaat ttagttacac aaaaaacaca aataaaaaaa gaaacttaca
    40441 aagcagaatt ttatgaagca aaatatatag tgtaaaaaat cttagggagg aaattttata
    40501 tgaattttaa aaaattgagt aatgctaaag tctcggtaat ggcagttgtt ttatcagttg
    40561 gaatattatc gggatactct gcgcttaata aacaagtaac attagtagta aggggagaag
    40621 aaagaactat atcaacattt agttctaatg taggagacct tttagaatct caaaacatta
    40681 gctatgatgc aaatgatata gtaactttag atgaaaatac aaagttatct aatggagata
    40741 aaatagaagt aattgatgta aaggaaaaaa cagttgtaga aactaaagac attccatttg
    40801 aagttacagt tgttgaagat ggctctttat taaagggtga ttctaaggtt aaagaagaag
    40861 gaaagtctgg taaaagtgaa ttaatatata aagaaactta tcacaatgga aagaaagtag
    40921 aaaaggaatt tgtgaaaaag gttgttaaag ctgagccagt aaataaggtt gtaagcaaag
    40981 ggacaaaggt agaaatgcaa gtagcctcat caaggggaga aagttcaaga agaatggctt
    41041 catcatcatc tagtagcagt agtagtaaca atggtaaaaa tatgagagtg gtagcaactg
    41101 catatactgg tcacagtata actgcaacag gaacaaaacc taagtgggga acaatagctg
    41161 tagaccctaa ggttatacca tatggaacta aagtttatat acctcaattt gacatggtgt
    41221 ttactgcaga agactgtggt ggagcaataa aaggaaataa aattgatatc tacatgaatg
    41281 attcaaaaac agtttataac tggggaagaa aaactataga tatacgtata ttaaaatagt
    41341 taaataattt atatttttac tggaaattat attttgatta tatagagaag aaactcttta
    41401 tagattctaa aaatataatt tccagttttt tattttggat atgtaataaa acaggtaaat
    41461 tttaaccatg tatagataaa agctatttaa attataattt actatcatat aaatctataa
    41521 aaattgttgc aaagagtcaa aatatatgat attatagatt tcgttgagaa ggatttcatt
    41581 atgggagtgg atgggtgccg gtgtgccctc tagtcttcaa aactagtatg aggggttaag
    41641 agcctcttag gtgggttcga ttcccacgca ttcccgccaa tatgtaaaag gtatctttta
    41701 attaaaagat acctttttaa atttgtttta agataattta gttttaatga tatataatat
    41761 tttgtattat ataatgtaaa ttttataata ctattattgt tcagataaaa gtctaggaga
    41821 gtgaaaagat ggaaaataat tttacaacga gaactagttt tctagttgga gatgatggga
    41881 tagaaaaact taataattca aatataatag tatttggagt tggaggagtt ggtagtttta
    41941 ctgttgaagc tttagcaaga gctggagtag gcaatattac tattgtagat tttgatgatg
    42001 tagatataac caatataaat agacaaatac cagccctaca ttcaactgta ggaagataca
    42061 aagttgatgt catggaagaa agaatattag atataaatcc taatatcaat ataaaaaaaa
    42121 taagaagtct ttataataaa gatactagtg acgaaatact aactgaaaga tatgattatg
    42181 ttgtggatgc gatagacatg gtaagttcca aaatacatct aattgaaact tgtgaaaaaa
    42241 aaggattgaa aataataagt tctatgggta tgggaaataa attagaccca actaaaatag
    42301 tcgttacaga tatacacaaa acaagtactt gtcctctagc taaagttatg aggaaagaac
    42361 ttagggatag aggtatcaaa aagttaaaag tagtatattc tactgaacaa ccaatagaac
    42421 ttaagaagaa agtaatgaat ggtagaaaag taacacctgg tagtgtatca tttgtcccat
    42481 ctgtaggagg tttaataatc gcatctgtaa tagtaaatga actattagga caataagttt
    42541 taaatatttt aatttataaa ttttatatac aaatttgaag gctagaagga tgaatataaa
    42601 gcaattttat attcatactt ttagcctagt tattttatat taccttattt tatgtagttg
    42661 tagctttatt ttttagatta tgtatctatt tcataattat attttgtaaa tataatttct
    42721 ccatcactat aaaaaacaat atctcctatt ctgtctgttc tataaattga tacatggttt
    42781 tgttttagat tattaataac ctccctatgt ggatgaccat attgattttt atatccacat
    42841 gatattgcag ctatatctgg actaattttt tttataaatt ctaaagatga agaagaatta
    42901 cttccatgat gacctatttt tataaaatta atattattta atttaaaaga atgtaaaatt
    42961 tctttttcat tttcttcttc agcatcaccc ataaataaaa aagaattatc attaaaagtt
    43021 aatttgaaaa ctatagaatt taaattagat tcttcttgta tatatgatgg acttaataca
    43081 tatatattta tattgttatc tatgtttaaa acatcatttt tatagagatg ctgaatagat
    43141 aagtttttat ccgtacaaga atttattaga ttttgataag cctcactatc agttgattgt
    43201 tcaggcatat atatggagtt tacattaaat ttttttataa tattatcaag acttcctatg
    43261 tggtctgaat ctggatgagt tgctattata atatcaatag tttttattct tttttgtcta
    43321 agataactaa taattatatt ttcgctatct tcatcacctc catcaattaa tatattctta
    43381 tttgtgggtg tttgaactaa aatactatca ccttgtccaa catcaatcat atgtatagat
    43441 agtagagatt ttttgtcaca gccgattaaa agtgatatta taataagtat tgataaaaaa
    43501 attttatttc tcaataaaaa atcactccat tcattacatg tttatataaa tttatgatgg
    43561 gtaatataag atatatatga cttattatat tttatatttt aaacaatata aatgaaatta
    43621 ataccataat aaaattggag ttttttatat atacaaaata aaatttttaa aattaagcaa
    43681 taaaaaaggt aggaggattt tatgtttttc aaagatattg aactaaattc aaaaaaagag
    43741 ttagacccat attttgattt agtagattat gaagcttgtg agtactgttt tagtacttta
    43801 tatatgtggc aacatgttta taagacagga tattatatag gtgaagattt tgccgtttta
    43861 gttggggaat acgaaggaga tagcttctca atattaccac ttgctaaaaa agataaactt
    43921 ccagaagttg tagattttgt ccttgaatat ttttctaaaa ataataaaaa aatatactta
    43981 agaggtatta ctactgaagt agtagagttt ttaaaagaaa aatatccagg tagatttgag
    44041 tatatagaag aaagagattt atttgactat atttatgatg cagaaagttt aagaactcta
    44101 gctggtaaaa agaatcaaaa gaagagaaac catataaact atttcttaaa agagtatgca
    44161 ggtagatatg aagctaaatt attagataaa gaaaactttg atgagtgttt agtactaatg
    44221 aaggaatggg aaagtaataa ggaagaaaat aatgaatttg atgaaagtat ggatgatgaa
    44281 ttaataggta tcaaaaagat atttaaccat tatgacatat taaaagataa ggtaaaagtg
    44341 tttggtgttt atgtagatgg aaaattagaa gcttttagta taggagagct tttaaatcca
    44401 aatatggcat tgattcatat agaaaaagct aatcctgata taagaggtct gtatccattt
    44461 ataaatcaac aatttttggt aagtgaattt aaggacgttg agtttgtaaa tagagaagaa
    44521 gatttaggta ttgaaggatt aagaaaagct aaactttctt atcatccttg cagatttgtt
    44581 gaaaagtaca gtgttaggga ggcttaatag actatatgga gattaggtat gctaaagaag
    44641 aagagataga aagtataaaa gagatttgga gttattgttt taacgatacg gagagtttta
    44701 tgaagtacta ttttaatgat aaatataaat ctgaaaatac tgtagtagct ttagatgaag
    44761 gaaaaattat ttcttctctt cagctaaatc agtataagtt attactaaat agcaaggtat
    44821 ataatacatc atatgtagta ggagtttcta cacttccaga gggaagagga gctggatata
    44881 tgaacaaagt aatgaaattt actttaaacg aattgtataa aaaagggcaa ttagtttcta
    44941 tattgatgcc tattgactat agactttata gaagatttgg atatgagcat tgttacgacc
    45001 agattgaata tactattaac acagatgatt taaaaaattt taagtcaagt ggaaaaatga
    45061 taaagtctaa tttatcacaa attgatgatt tgatacaaat agatagaact tttttaaatg
    45121 aggttaatgg taatgtgtta aaagatgaac attattatga aaacttattt aaagagattc
    45181 aaagtgaaga tggattttta tacattcatg aaggaaatga aaaagatgga tatatagttt
    45241 attttcttca ggaagataaa atgtttgtca gagagttatt ttataaaaat atagatgccc
    45301 ttaaatcaat gcttaaattt atatataatc acaatactca atgtaagata gttactatat
    45361 ctactcctac aatagataag ataagattta tattagacaa ccctaaagat agtgatataa
    45421 aaataaaacc ttttatgatg ggaagagtta taaatgtaaa gaagtttatt gaagatatag
    45481 atattgagaa tgatattaat agctcattta atttattaat agaagacaag tttatagatg
    45541 aaaataatgg tctatttaaa atttctatac agaataagaa ggtatctgta gagcagttag
    45601 ataaaaaagg tgcagaaaag cctcaagaag attttgatat taaattagat ataaatacct
    45661 taacacagtt atcattttct tatatagatg taaatgaagc tattttctta aatgatataa
    45721 aagatgtttc agaagaaaca ctagaaacac ttaattgtat tttttctaaa aaaaataact
    45781 atataaatga atatatatag gtagagtacg ttaaaagatt ttaaaaatct tttgacgtat
    45841 ttttttgttt agataacaat ttatcttgtt taaaaatttt ctatttgaaa ataatctaaa
    45901 taatatactt ttatatggga gtgattataa ttcaaataag aagaccatta ttaattatat
    45961 taatgtttgt ggtagctata tcatttatca ttacaaataa cacaaaaaac gacgaagaac
    46021 ttaatgataa gataataact atacaaggag ttgtcaaagg aaaaattgaa aagaaaagat
    46081 acaatcagta caaggtaggg gtttttctaa taaatgatta tacaaaaaat aaaaatttga
    46141 agattggtca gaaagttaat attacaggta aattcaaaag tttagataaa atgaagtatg
    46201 atgattttga ttatggaagg tatataaaaa gtactggata taaaggtata gtgtatataa
    46261 ataactataa aattattgat aaaaataaac tttactcttt aataggggaa ataaagtttt
    46321 atattagtaa aacttatagg tacttatata agaaaaactc agattttata aattctatac
    46381 tattagcaga agttgaaaat ttgactgagg aacaaaaaga aatttttact agaactggaa
    46441 ctagtcatgt aatatctata tcaggtcttc atacaggaat attatgtgta attatatcct
    46501 ttctattaag aggtataaat aaattgtata aattattaat actgtcgatt tttataactt
    46561 tatattgtat aatggtaggt gcgtctccat ccataattag gtctatagca tttgttatga
    46621 ttttttattt atcaatattt attgatagaa agaaagatgg aatatcggca ttgtctctaa
    46681 ttgggataat tttaattatg aataacccct atgttatata taatgtaagt tttcaattgt
    46741 cttttttagc tacactttct atattaatat tctataataa aataaatagt attataaaat
    46801 taagtatggt atcattgaca atatcatcaa atatattaac tttacctata atttattata
    46861 catttaaagg tataccattg ctttcaatta taggaaattt aattatagta ccatttgtgg
    46921 gagtaataat gtatttaagt attgcaagtt taatcgtatt taaagtaagt gtagtaatag
    46981 ctaaaattat atcttttttt aatagtacat ttatagaaag catatttttt ttactagaaa
    47041 aaatcagcaa tttaagtttt gcatacatta atatagaaaa tcctaaattt tatattgttg
    47101 ttatttatta cataggagtg tttttttaca tattttacat agaaggaaaa gagataaagg
    47161 agcaagagaa tgaattacaa ggatattata aggaatgtaa aagagaaaaa ctttgaaaaa
    47221 atgtatcttt tttatggaag agagtattat ttaattgaga atgcaataaa agcatttaaa
    47281 gatagtctaa acgagggaat gcttgatttt aacttagata taatagatgg gaaggaaata
    47341 gtcttaaatc agcttataag ctctatagaa acacttccat ttatggatga tagaaagata
    47401 gtaataataa aagactttga actattaaaa ggaaagaaaa agaattttac agatagtgat
    47461 gagaaatact taatagagca tttagacaat attccagaca ccacaactat agtttttgtt
    47521 gtatatggag atgtagacaa aagaaaatca ttagttaaga aaataggaaa caatggaatt
    47581 gtttttgatt gtgataagct ttctgatatg gatttgttta aatggataaa aaaatctttt
    47641 gctttaaatg atgttataat agataattct caaatcatgt attttattga acaagaagga
    47701 tacagagata agagtagtga aaagacatta tctgatttag aaaatgaaat aaataaaata
    47761 agttcatttg ttggtaaagg gaataatgta accaatgatg taattgataa attatctcaa
    47821 aaaaaagttg agaatgatat attcaaatta atcgattata ttggagaaca aaatgcttct
    47881 aatgcaatga aaatattaaa tgatatgata caagaaggcg aatctgtatt aggtatattt
    47941 tctatgatag caagacaatt taaaataatt atgcaagtaa gacagttaca acttgatgga
    48001 tattcaacaa aacttatagc tgataaatta aaaatgcatc aatttgttgt aggaaaagca
    48061 ttaaagcaaa ctaaaaattt ttctgatgat ataattgtgg aaatattaaa ctatatatta
    48121 gaaagtgatt ataaaataaa gacaggtctt ataagagata ctttagcagt tgaaatgttg
    48181 gttagtagat actgtaaaag agaagcaatt taaaaaatct atatattaat aaaaaataaa
    48241 tagcaagata tgttatagtt cagagtagat gtaagctaaa ttaagtttga tatacaatca
    48301 actataatat gtctaactat ttatttttta ttgtataaat ttacaaaata aaaaacccct
    48361 acataggggt tattatatat aagaaatata aactggtaat taagcgttca taccgtttaa
    48421 tttttgagct aatttagcta cttttctagc tgcagcattc ttatgtatag ttcctttaga
    48481 agctacttgg tatattcttt tttgagcgta ttggaactta gcaacagcat cctctctgtt
    48541 tccagctgca acagcatctt cgaatcttct tattgcagtt tttatttgag attttctaac
    48601 tctatttaaa gcagttttct tttcgataac acttattctt ttcttagctg attttatatt
    48661 tgccaccgtg ttcacctccc tgtatttttt tatcatattc atcgtcaaca tattagattt
    48721 taacagaaat aaatctaaaa atcaaggatt attatttata tattttaata atgtttttta
    48781 ttttgatttt ttagactgta aattgtgtat aaataatttg caatatcttg tttttaaatt
    48841 ggtatatttt gtgttttaaa tattttgaca tatataaatt aatattttat ttttgtaaca
    48901 aatattttga gataatacaa actattaaca tacattttga tagtatttcc aataattata
    48961 agataataca agaaattact catttttgta aatttaatga aaaattataa aaatataaat
    49021 ttatatgctt aattaagata atttttttca ttagtatgta tgatagatgc atcaaacaat
    49081 ataactaata tgttagaagg ttatatgtaa ttaatgtcag tgtttatata gaatagcatt
    49141 tgtagcattt attatagttg taattactat ttatatcata gacttgaata gtctaaaaaa
    49201 atagactata atatttttat agactaaaga aagggctgat aagatggaca tagcaaaact
    49261 aattttaaat cctgcaaggc ttcgtatttt acaatatatt cgactttatg gcagtgttcg
    49321 tacatctgat attgtaaagt atttaaatga tattcctcgt gcaacagttt atcaccatgt
    49381 aaaaatttta gaagagaaca atatgattga agtaattaaa gaaaatcgtg tgcgtggtac
    49441 tattgaaaag gtttatgcac taaaggaata tacaacatct atggaaggag agaccttcgt
    49501 tgcactttct acagcatttt atgtaggtct gatgcaggaa atgaatgaat actttagcag
    49561 aaaagagcaa gaccataaaa aggataatgt atttttctct tcagcattac tatatatgag
    49621 tgataatgaa tatgaaaatc ttcttaaaag tatagctgat ttattgaaac catatataga
    49681 acaaaaacct aaatcaaatc taaaacttag aaaactttca attatatctt ctccacctgt
    49741 agctgataat gataaaacaa aataacatgc aacccatttt tataaaagga ggttatatat
    49801 gaaatttcat gagtttggaa ataaaaacag accacatatt atgttgattc atgggggagg
    49861 gaatgcatgg tggaactatt tgcgacaagc agaagttttg tctaacaaat atcatgtgat
    49921 acttcctaca ttggatggtc atggagaaga atatgaaaca acatacattt ctacagagga
    49981 tacagcagat aagttgatat catatataga tgaaaattgc agtggacatc ttttcgcttt
    50041 gtgtggggta tcacttggtg gtcaaattgt catggaactt ttatctcgaa aacctaatat
    50101 tactaaaaaa gcaattattg atggtagtat ttgctaccca agacctctta tggcaaggtt
    50161 ttgtattgct ggtattcgat tttttggagg acttttgttt agtgagaagg cttgtcgctt
    50221 tcaaattgct atgatgccaa aattgttacc tgaaaatatg caatatccag ataaaataaa
    50281 agcgtattat atgacagata tgccacatgt aagaaaagaa acattctata atatgtatcg
    50341 tacttacatg atgaactata cacttaaaga gaatgttaaa aaaaccacag cacaagtaat
    50401 gtactggtat ggagaaaaag aaatgaagtg tgtcaaaaaa tctgcaaaac tgtttcagtc
    50461 ttatgtgccc tcttgtgaga tttatgaagc taagagctat aatcatgggt atttatcact
    50521 ttatcttcca aatgaatggt tggaaattgc agaaccattt ttccaaaagg aataaaggtg
    50581 ttaggtgatt attgtataat tattgctgtt tttttatata gtaaataaat taggtataaa
    50641 tataaaaaat tattttagtt aatatattag tgaaagctta ataggaaaat tataaataga
    50701 ttaaaggtag cacctatata aatagttgct acctttttct gtttgtaaat aaatgataga
    50761 taagaaggtt tactgacaaa tcactgacta aacccaattt tcttacattg aaagccttaa
    50821 ttttacttgt tttaaataaa tttacaattt cttgttataa aatactaaat tttgttaaca
    50881 attataatta gcatttaatt tatactggag gtttatatga ttagtgtaag aacagattta
    50941 gctttagaag ctagtgaaat gtgtgaaaag tctcaagaag gaagtagtat tcctggtgta
    51001 aaaatagaaa ctaaagaatt agaaaattgc attgtaacta aagttgaagt aatagacagg
    51061 caaggcgcag agataatgaa taaagatata ggaaagtata taactctgga aagtaatctt
    51121 atgaagtttg atgatgatga gtcaagagaa gaaatgataa gttatttaaa agaggagtta
    51181 gtagatatat ttggccaaga caaaaataaa aaaaccctgg taattggtct tggaaataga
    51241 aatattactt ctgatgcgtt aggaccaaag agtgtatcaa aaacacttgt aactagacat
    51301 ctttttaaaa attataataa agactatgat gatgatttca ctgaggtatc agctttaagc
    51361 ccaggagtta tgggtgttac tggaatagaa actagtgaaa tagtaaaatc attggttgag
    51421 aaggttaagc cagatagagt agtagcaata gatgcattgg cttcaagaaa aatggaaaga
    51481 gtaaactcta ctatacagat atcaacagca ggaatatcac ctggtggagg tgttggcaat
    51541 actagaaaat ctctaactaa agaaacttta ggcgtggatg ttattgcaat aggcgttcca
    51601 acggtggttg atgcagcaac tcttacaata gatgtcttag atatggcaat agacaattta
    51661 atagctcaat cagaagaaac agaaagtttt tatgaaatgt tgaaaaaact taaagaagaa
    51721 gaaaaatatc atctaataaa agattcgtta gacccatatg acaagaactt aatagtaaca
    51781 ccaaaggata tagatgatac aatcgaaaat ctatctataa taataagtga aggcttaaat
    51841 aggtctttac atccaggtag attggtataa aataaggagg agcaattatg tttaaaaaat
    51901 gcattaaagt agtaaccttg acttttatat tagtatgcat tttaccagga aaatcattag
    51961 ctttgaatca agatgatttt ttaaagtttt tagtaaattc atcttatcca gaagctaaag
    52021 tcgaaggaaa tgatacagaa aataaaaaga ataataaaaa taaagaaaca agtaaggaaa
    52081 ataaggaaga aagtaaagaa ggaaacacta aatctaaaga tgcaagtaaa gttgataata
    52141 aaaaagagag tgaaaaagaa tatataaaac tttatgttgg taaagaaaat gttccagata
    52201 ttgagtcaaa aaattcagac acaactgaaa ctaacacaac atctagttca gattataagg
    52261 atgatttaag agtaaccaaa gaaaatccaa gaattttgat atatcatact catggatgtg
    52321 agacttattc aaattcacct gatggaaatt atcattcaag agataagaaa aattcagtaa
    52381 tggaagtagg aagtgcatta actagtgctt tagatagcaa aggatggggt gtagtccata
    52441 ctactaaata ccatgactat ccatcttata ataactctta tgcaagtagc ttaaaaacaa
    52501 tacaaagtat attacctaaa tataactcag tggatatagc gatagactta catagagatg
    52561 ctagggattt aactaatcca gccactaagg aaaaagacca tttaaaatat acaactatga
    52621 taaatggaga gagagtatca aagttcttct ttgttgtagg aggtaaaaat acaaatagaa
    52681 aacaacttag agctttagca gaagatataa ctgcttttgc tgagaaaaag tatcctggtc
    52741 tagtatctcc aatagtagaa aaagactatg ctagattcaa tcagtttgca gttaagaatc
    52801 atatgttagt agaaataggg aataacgcaa caagtgtaga agaatctaag gctactacaa
    52861 agtatttagc cgagattttg gatgaatatt ttaaacaaaa aaattagagc tttaagttat
    52921 aattaggagc atgctaaatg agccgattag aaaaaaatat agaaagtaaa agtaaactaa
    52981 gaaaatacaa gtatattatg agaatcttat ttttgattac tatgattata tgtacatcag
    53041 tttgtgtatt tatagtggac agtaatgcaa aaagtatgct aggaatgaaa caatatgatt
    53101 ttccaagtat taaatttgat ataacaaaat ttgattttga cataccaaat tttgatatac
    53161 atgaaatcat aaaaaaattt aataagtagt aataagtgaa taaggtttat tgattaaaat
    53221 aagccttatt ttagttatat atttttaatg tataaaataa aaattcatta actgtatttt
    53281 ataggattta ctttaagttt atgatattat ataatattta gtgttagact tgataatcca
    53341 catataatgt ggataatttt gtttagtgcc aattagttta tattcaaaaa ttttaaattt
    53401 ggtatataaa gagtttttag ataatgtaaa ataataacta taagaataat caagaggagg
    53461 gaattttaag gtggacaata aacaaagtag aactagaaat tttagtataa ttgcacatat
    53521 agaccatgga aagtctacct tagctgatag attaatacaa caaactgggc ttgttagtga
    53581 aagagacatg aaaagtcaat tacttgacaa tatggacctt gaaagagaaa gaggaatcac
    53641 tataaagctt caaaacataa gattaatgta taaagcgaag gatggaaatg aatattattt
    53701 aaatcttata gatacacctg gacatgtaga ctttaactat gaggtatcaa gaagtttagc
    53761 tgcatgtgaa ggagcactat tagtagttga tgcagctcaa ggtgttgagg cacaaacttt
    53821 agccaatgtt tatcttgcta tagaccaaga tttagaaata ttaccaataa taaataaaat
    53881 agatttacca agtgcaagac cagaggaagt aaaaaatgaa atagaagatt taatagggct
    53941 tgattcaagt gaagctcctc ttatttcagc taaaactggt ttaaacatag aagatgtttt
    54001 agaagatatt gtaaaaaatg ttcctccacc taaaggagat aatgaagctc cattaaaggc
    54061 attaatattc gattcttact atgatgctta caaaggtgtt gtagcttatg ttagagtatt
    54121 tgaaggaact gttaaaaagg gtatgacaat aaaaatgatg aataccaata aaaagtttga
    54181 ggtaactgaa gttggtgtta tggctccagg tcaaactgaa cttagtgaat tatcagcagg
    54241 tgatgttggt tatattgctg ctagtataaa agatataaga agttgtcgtg ttggtgatac
    54301 aataacagat tcaaataatc ctacagaaga acctttacca ggatacaaaa aagctactcc
    54361 aatggtatat tgtggtatat atccaggaga aggagaaaag tatgagaatg ttagagatgc
    54421 tcttgaaaag cttcaagtaa atgatgctgc acttgaatat gaagctgaga cttcagcagc
    54481 actaggattt ggttttagat gtggtttctt aggtctttta catatggaga taatgcaaga
    54541 aagacttgag agagaattta accttgatat aattactaca gctccatctg ttatatatag
    54601 agttacaaaa atggatggag aggttgtaat gatacaaaat cctgcaaact taccagaacc
    54661 atctgagata aagatgatag aagagcctat agtaaaagga gatataatag ttcctaaaga
    54721 ctatgtgggt gttgttatgg agctttgcca ggaaagacgt ggaaatatgt taaatatgga
    54781 atatatagat gatagaagag taatgcttca ctatgacctt cctctcaatg aagttgttta
    54841 cgatttcttt gatgctttaa aatcaagaac tagaggttat ggttctcttg attatgaggt
    54901 taaaggttat gtagcatcta cacttgtaaa acttgatata ttaatcaata aagagcaagt
    54961 ggatgcactt agttttattg tccatgagac acgtgctttc cctagaggaa aggcaatgtg
    55021 tgagaaatta aaaggagaaa ttccaagaca tcagtttgct ataccaatac aagctgctgt
    55081 tggtaataag gttattgcaa gagaaacaat aagcgctcta agaaaagatg ttcttgctaa
    55141 atgttatggt ggagatatat ctcgtaagaa gaaacttctt gaaaaacaaa aagaaggtaa
    55201 gaagcgtatg agacaaattg gttctgttga agttcctcaa aaagcattta tgtctgtgct
    55261 taaattagat gagtaaatcc ttataaattt agataaagat atttaaaagc tagagtgatt
    55321 ttagaattat ttctaaatta gtctagcttt tttatggtat attttaagta aactcataga
    55381 gaatataagt aagaatatta aagaagaata aaaaggtgat atttatgatt aatatagaaa
    55441 ttcctaaaaa agtagactat ataattaaag aattagaaaa gaatggttat gaagcttata
    55501 tagttggagg atgtgttaga gattgtttat tagaaagagt tccaaacgat tgggatataa
    55561 caactagtgc tagaccagaa gtggtagtag aattatttga aaaaacaatt ccaactggta
    55621 tacaacatgg gactgtaaca gttatgattg aacatgaacc atttgaagtg acgacttata
    55681 gaattgatgg aaattatagt gatggtagac atccagattc aatagaattt acaaataaca
    55741 tagttaagga cttgtcaaga agagatttta ctatcaattc aattgcatac aattcaaaga
    55801 caggattagt cgacccattt aatggctatg aagatataca aaataagtat atacgttgtg
    55861 ttggaaatcc agtagataga tttgaagaag atgcacttag aatgcttaga gcagttagat
    55921 tttcagcaca actcaatttt aaaatagctg aaggtactaa gcaaagtatt cataaaaaag
    55981 cagatttgat aaaaaatgtt tctattgaaa gaatccagac agagtttaat aaaatattag
    56041 tatctgattc atctaaatta aacttattaa aatcaacagg tttgttgaaa tttataattc
    56101 ctgaaatatg tgaattagaa gatgttactc aacacaatcc atatcacatc tatgatgtac
    56161 aaaaacatac tttaatagct acagaagtaa ttgaagatga actgtattta aaacttacaa
    56221 tgttgtttca tgatttaggt aaaaaagtaa ctaaaacaac tgataaaaat ggtgttgacc
    56281 atttttatac tcatagtaga gaatctgtaa agattgcaaa gaagattttg aaaagactta
    56341 agtatgataa ttatactatt aataaagttt taatattaat acaatatcat gattatagaa
    56401 tagaacctaa aaggaagata attaaaaagt tattaaataa acttgaagat gttgaattat
    56461 ttgaagattt aataaaagtt aattgggctg atacacttgc aaaaaatcca aagtatgcaa
    56521 aacaaaagat attaaatctt attgagtgtg aaaaagaatt taaacatata ataaatcaaa
    56581 aggagtgctt taatcttaaa gatttagcta ttaatggaaa agatttgata tctataggta
    56641 taaaaccagg taaagatata ggatatattt taaataagat gcttgaaata gtcataaata
    56701 atccagagtt aaatgaaaaa gaaatactaa aagaaaaagc attaaatata tatacatttt
    56761 agattcaaat ataaaaaatt taattacttt aaaaaacata gaataaaata cttatttaga
    56821 taaaataaat aatttttaga gaatatttta gaagttacga ttgtatgatt tttaaatgca
    56881 taggcattta ctctaggact atagactaat ataaaaaaaa actttgggaa tactaaaacc
    56941 ataaatttat aaaattaata ttttatatac tgtaaaacag tgaggaggga cagtatgcat
    57001 actcaactac aaaagactat tggtctttca gcagctcttt ctactgttgt aggtatggtt
    57061 ataggttcgg gagttttttt taagccacaa gcaatataca ctacaactaa tggagctcca
    57121 ggtctaggta ttatagcgtg gcttttaggt ggttttataa caataactgc tgggcttaca
    57181 gctacagaaa tttcagctgc tataccaaaa actggtggta tgatgattta tatcgaagaa
    57241 atatatggag aaaagttagg ttttttaact ggatggatgc aaactgtatt atttttccca
    57301 ggtacatcag cggcattagg agtaatattt gctcaacaag catctgaact tttaggaatg
    57361 agcccaaata atatggcaaa tgtacttcct atagcaattg gagttatact atttttagcg
    57421 ttattaaata taataggttc atccttagga ggaaaagttc agacagtagc cactattgga
    57481 aagatgatac ctttaatttt aataatagtc tttggattta ttaaaggtca aagtagtgaa
    57541 gtattaaatc catttgtagg agatggtgta aatgcatcaa atgcacttgg acaagtatta
    57601 atagctactt tgtttgcata tgatggttgg ataaatgttg gagctatatc aggagaaatg
    57661 aagtctccag agaaagattt accaagagca atagttggtg gtttatcatt agttatggca
    57721 gtttatatta taataaatat agcttatctt tgggtagtac cagcaagtga attagcaaca
    57781 gttacttccc cagctacatt agtagcaaca agattgtttg gaaatatagg tggaaaagta
    57841 ataactgtgg gtatattaat atcagtattt gggacattga atggatattt attaacaggt
    57901 tcaaggatac cttatacatt agctgaaatg ggaactttac cagcatctaa aactctttta
    57961 aaagtaaatt ctggaggttc tcctgtaaat tcaatactac ttataactgt gttagcctgt
    58021 gtatatgcat tatctggtca atttaatctt ttgacagact taacaatatt ttcaatatgg
    58081 gtattttatg tattgacttt tataggtgtt atgaggctta gaagacaaaa gccagattta
    58141 cacagaccat ataaagtccc tttatatcca ataataccaa ttatagctat attaggtgga
    58201 ctgtttgtaa taataaatca aatattgact tcaacagtca tatctttagg cggaatattt
    58261 ataacactat taggtttacc agtttattat tatatgaaaa aaagataact acttaattta
    58321 agttagataa atttgggtaa aggtgaaaat taacttttat ccaaattttt tatactgtta
    58381 tacaatataa gtattatata ttgcttgatg tgctattttg tttgatttat aatttagtaa
    58441 ttgatgtttt aagataattt aagaaatgag gagtgaaaga tgctaggact ttatgtacat
    58501 attccatttt gtgtgaaaaa atgtaagtat tgtgatttta attcttataa aatggacata
    58561 gattcaaaaa aaagatatat agaagactta aaaatagaaa tggaattata tagtaataaa
    58621 ttatataaag ataataaata taaaaataaa gaatgctgta gtctaaataa aaatgacaaa
    58681 ataacgagta tatttgtagg gggaggtaca cctagtatac taacctctga tgaaataaga
    58741 gaagtattta taagtataaa agaaatgttt gatatagatg agaatgcaga aataactata
    58801 gagtgtaatc ctgggacatt aacattagaa aaattaaaaa ctatgaaaga gattggcata
    58861 aatagactta gtatagggct acaagctatt caagaaaagc atttgaactt tataggaaga
    58921 atacatactt atgaagaatt tgagaaaaac tataaagatg cattaagtgt aggttttaaa
    58981 aatattaata tagatttaat gtacagtctt ccaaatcaaa ctctatgtga ttggaaggaa
    59041 actcttgaaa aagttgtaca cttaaatcca acacatatat cagcttattc ccttatacta
    59101 gaagaaggaa ctgaactata caatatgtat gaaagtaata aatttgaact tatagatgaa
    59161 aatgtagata tagaaatgta tgagtataca ataaactatt taaagtcaaa aggatataat
    59221 caatatgaaa tatcaaacta ctcaaaagaa ggctataatt gtgagcataa tattttatat
    59281 tgggaatgtg aacattatat agggattgga gcaggagctt ctggctatat taatgagaac
    59341 agatacaata atgtagaatc tttagaagat tatcatttaa gtttggtaaa aagagaaaaa
    59401 ccaatacaag aaaatgaaat tctttctgag aaagatatga tagaagaaaa gatatttatg
    59461 gggcttagaa tgaataaagg cataaaattt gaagatttta aaaaaaaatt tggaatagat
    59521 tttagagaga agtataataa gcaaatagaa atgctattag ctagaaagct tataaatcag
    59581 agctttgaag gtatacaatt aactcaaaaa ggaagagaaa tatctaatag tgtatttata
    59641 gaatttatgg aataattttt aaggtgttga caaaataaat ttataatggt atataatata
    59701 tataatcttt ttagcactcg aacttagtga gtgctaacag ctaggaggta taataatatg
    59761 gaattaaatg aaagaaaatt aaatatcctc aaagctatag ttaaagatta tatagaaaca
    59821 gctgaagcta taggttctag aacaatatct aaaagacatg atttaggtgt tagtgctgct
    59881 accataagaa atgaaatggc tgaccttgaa gaattagggt atttaattca gcctcatact
    59941 tctgcgggta gagttccatc tgaaaaaggc tataagttat atgtaaactc tcttatgagt
    60001 aaaagcgaat tggatgataa tgataagatt cttattgaac aatgtatgaa tcataatata
    60061 aatcatataa aagaattgat tcatgaaact tctaagctat tatcgcaact aacaaactat
    60121 acaactgtag cagttactaa gagtttaata aatcaaagtg ttataaagca catacagttg
    60181 gttgctatga atgacaataa tattttactt atagttgtaa cagataaagg ggacttaaaa
    60241 aaagctaacc ttacaactaa tgtatattta gatcaatcta agttaaattt gatttctgat
    60301 aatcttacaa ggaagctctt aggtaaaagt ataacagatt tggatgataa tctaattgct
    60361 tttattaaat acgaaataag tgagtattct gggcttatag atgagctttt aaatgctttg
    60421 aactcaaata tgaaagaaga agatttttct ctatcattaa atggagctac taacatattt
    60481 agttatccag aatttaatga tgtattaaaa gcaaagtcat ttttaaatat gttggaaaaa
    60541 aaggaaacaa tagctgacat aattaaatca aagggaatac aaaaagacaa tctaaatata
    60601 ataattggta gtgataatga ttgtgaactg gcacaggatt gtagtatagt tacagcaact
    60661 tataatgtag atagagactt ggttgggcga ataagcttta taggccctac cagaatggat
    60721 tatgctagaa tttactctat aataaattat atgagtttat taattaatag aaagtaaaga
    60781 aattttaaat tgcgaggtgt aaagtcttgg ataaaaaaaa tgagcaacag gaagtaagag
    60841 aagaaaatga tacttctatt aaccaagaat cggaaactca agtagagtta gaagaggaag
    60901 ttgttaatga agaatgtgaa acatcaagtg aaaaaactga tgaaaaagaa gttgatgatg
    60961 aaaatgtaac agatataaat tctaagttag cagaaaaaaa attgcaggat gagttggatg
    61021 aattaaatga taaatatcaa agacttcaag ccgaatatgc aaactacaga agaagaactc
    61081 aacaagagaa agagacaata ggcgtatttg caaatgaaaa aataataact gaattgatac
    61141 cagttataga tagtatggaa agagccttag atgcatgtga agataaggaa gatactatgt
    61201 ataagggtat aagccttgta cataaacaat taatagacac tttagtaaaa tttggagtag
    61261 aagaaataga agcagaatct aaggaatttg accctaatct acatctagca gttatgcaag
    61321 aaagtgtaga tggagttgaa gcaaatcaaa tagtaatggt acttcaaaaa ggatataagc
    61381 taggaactaa agttgtaaga ccttcaatgg ttaaagtttc ttgctaagta taaattaaag
    61441 gttaaattat ttaacctaat ataaaatatt aaaataagta aaacttaatt atataattac
    61501 tcgaggagga ttttagtcat gggaaaaata ataggaatag atttaggaac aacaaattca
    61561 tgtgttgcag tgttagaagg tggagaagca caaataatag caaatagtga aggtatgaga
    61621 actactccat cagtagtagc atttacaaaa gatggtgaaa gaatagttgg agaacctgca
    61681 aaaagacaag cagttacaaa tgcagataaa acaataactt ctataaaaac tcatatggga
    61741 actgattata aagtaaatat agatggaaaa tcatatactc cacaagaaat atcagcaata
    61801 atattacaaa aattaaaatc agatgcagaa agttacttag gacaaacagt aacagaagca
    61861 gttataacag taccagctta ctttacagat gctcaaagac aagcaactaa agatgctggt
    61921 agaatagcag ggcttgatgt taagagaata ataaatgagc caacagcagc agctcttgct
    61981 tatggtatgg ataaattaga ccaagaaaag aaaatattag tatttgactt aggtggagga
    62041 acttttgacg tatctatact tgaaatagga gatggaactt ttgaagtttt agctacagct
    62101 ggtaacaata gattaggtgg agatgacttt gaccaaatag taatagatta tttagcagag
    62161 gaatttaaaa aagctgaagg tgtagattta agaaatgata aaatggctct tcaaagatta
    62221 aaagaagcag cagaaaaggc taagaaagaa ttatcatcaa caatgagttc aaacataaac
    62281 ttacctttca taactgctac agcagaagga ccaaaacact taaatataga tttatcaaga
    62341 gctaaatttg aagaattaac tagaggttta gttgaaaaaa ctatggaacc aactaagaca
    62401 gctttacaag atgcaggact ttctacaggt gatatagatg atgtattatt agtaggtggt
    62461 tctacaagaa taccagcagt acaagaagct gttaagaagt ttataggaaa agaacctcat
    62521 aaaggtataa acccagatga gtgtgttgca gcaggtgctt ctatacaagc tggagtttta
    62581 gcaggggatg ttaaagactt attattacta gatgttactc cattatctct tggtatagaa
    62641 actatgggta atgtaatgac taagataata gaaagaaata ctacaatacc aactaagaag
    62701 tctcaaatat tctcaactgc tgctgataac caaacagctg ttgatataca tgttcttcaa
    62761 ggtgaaagaa gtatggctta tgacaataca actttaggaa gattccaatt aacagatata
    62821 ccaccagcac aaagaggaat acctcaaata gaagttactt ttgatataga tgcaaatggt
    62881 atagttaatg tttcagctaa agatttaggt acaggaaaag agcaaaaaat aactataaca
    62941 tcaaacacta atttatcaga agcagaaata gagcaaaaga taaaagaagc agaaatgaat
    63001 gcagaagctg acaaacaaaa gaaagaaaaa atagaagcat tcaatcaagc tgaatctact
    63061 atatatcaaa ctgaaaaaac tttaaatgaa cttggagata aaataagttc aggtgaaaaa
    63121 gaggatatag aaaaagctat agcagactta aaagctgtaa aagataatca agatgctaca
    63181 gcagaagaac ttaagaaagc tacagatgaa gtaatgacta agttccaaaa agtatctcaa
    63241 gaaatgtacc aaaaagcagc tcaagaacaa caagcggcac aaggtgcaga acaagcacaa
    63301 gacaatggac ctaaagatga caatgtagta gatgctgact ttaaagaagt agatgaagat
    63361 aaataagcta tataatatgt aacactaaat gataattgga acatatatga tttgtgaaaa
    63421 tcatatagat gttaaagata tatggacaat atacatcata aagaatataa tatatcatag
    63481 attatataac ttaaagtaga atataagaat taatgatagc ttgtagttta ttattctaca
    63541 agctatcgtt ttgtaaaatg aaggtggtgt caatttttga gtacaaaaag ggattattat
    63601 gaagtcttag gtatcagtaa aggtgcagaa gctcaagaga taaaaaaagc ttatagaaaa
    63661 ttagcaatga agtaccatcc agatagaaat cctggagata aagaggcgga agaaaaattt
    63721 aaagagataa atgaagctta tgaagttcta tctgatgata caaagagaaa aacttatgac
    63781 cagtttggac atgatgggct aaatggtcaa ggcggttttg gtggtcaagg aggatttggc
    63841 ggtcaaggct ttggtggttt tgaagatatg ttcggagata tatttggtga catgtttgga
    63901 ggaagcttcg gaggtggaag agcaagaaga agagggcctc aacgtggtgc agatataaga
    63961 cagagtgtta ctatatcttt tgaagaagct gcatttggta aaaagatgtc tataaaagta
    64021 aatagaagtg aagaatgtga agaatgtaat ggaactggag caaaaccagg aacatcaaag
    64081 aaaacttgtt caacttgtaa tggaactggt caagttagaa ctgttcaaag aactccattt
    64141 ggtaatatag caagttcaag accatgtagt gcttgtaatg gaactggaga agtgattgaa
    64201 tctccatgta gtaaatgtca tggaactgga aatacaagaa aagttaagac tatagaagta
    64261 gatatacctg ctggtataga tgatggtcaa atgataaaac tttctggtca aggtgaagta
    64321 ggagaaaaag gtgctccaag aggagactta tatattgtag ttaatgttaa gtcacatcca
    64381 ctatttacta gagatggaaa tgatatttat tttgaaatgc caattacatt tgttcaagca
    64441 actttaggtg atgagataga agtacctact ttggatggaa aagttaaata tagtgtgcca
    64501 gaggggacac aaactggaac tgtatttaga cttaaagaga aaggaatccc tagaattaga
    64561 ggtaattcaa gaggagacca atatgttaag gttgtagttg aaattcctaa aaaattaaac
    64621 gataagcaaa aagaactatt gagagaattt gcgaaggagt gtgggtcgaa cgtccacgaa
    64681 aagaagaaaa ccttcggaca aaagatagaa gatatgttta agaaaaagta gttaaagtag
    64741 ccaatatata atcatatttt taaaatctta gttatttata agattgtcaa aggagatatt
    64801 atgattttta tattggctat ttttgtataa aaaataaatg tgcataaaat aaaactgaat
    64861 ataaataatt ttctgaaaaa tacttgtcct aaaatatata atatgctata atataatcaa
    64921 ataaaagaaa ggggtgattc cagtgggaac ggatgtggca ctgccaaatg atgaagaaaa
    64981 ctttattgta atatacaaaa taaaattaga tacttttagt gctagattaa gtactggaaa
    65041 aactcatgag ctgggataat tattgtaatt acctagactc aaacttttag tagtaaaata
    65101 gtaatattat atagacaagg tatctaattt ttaaatcttt tgtatgaatt aaaattttta
    65161 taaagggtat atctgattag aatgtaatta gggaaaccta gttgtgaatt acttttagta
    65221 tatacatgtg taaagaaata tgtatatggt attggttatt gtgctagatg tgtatgtaaa
    65281 ggaatatgtg tctagttggg tatatgtaaa gaaatatact tataatctat gaaaaatttt
    65341 tagtataaat tgctaaaaca ttgagattgt tttttataga aagttagttt ataccaacta
    65401 aaaatgtgct taagatttgt ttgatgttta attataaata aggttgtaga taaaaaaata
    65461 agtaaagaca aaggtttaaa atacttgctt taaatatagt ttgttttgaa cacttgccaa
    65521 attaaaataa ttaataaaat agacatcttc tcatagtaaa atatactgtg agaggatgtt
    65581 tttgctttgt tcataaactt ttatgaaaaa tttgcatagt gtcacatttt aatatactat
    65641 atatataata aaatatagat aaaattaaat gattcaaaag agaaaggtga aaagagatgt
    65701 attatatagg tgtagacata ggaggaacag gtatacaagc aggagtagtt gataactatg
    65761 ggaaaataat ttttaggtca gagtgtaaaa cagtaattga aaaaggcttt gaaggaatac
    65821 ttaatgacat aaaaataatg atttataagt tgttggaaga taataaactt actatgagtg
    65881 acataaaatc tattggattt ggtgttccag gttttataaa taaagaagga ttagtaactt
    65941 gtgtaaattt aaaatggaat aaaaaagctt ttaataaaga gttaaaaaga agatttccag
    66001 atgttgaaat tcatggagaa aatgatgcaa cagtagcagc acttggagaa gcaaagtttg
    66061 gaagtatgaa aggtgctaat gttggagtat tatatacttt aggaactgga gtaggtggag
    66121 gaatagtaat taatcaaaaa gtcttttctg gagcacatgg attgggttca gaaataggtc
    66181 atcaaattat aggagaaaac tattttaatt gtaattgtgg aaataatggt tgtgtagaaa
    66241 ctttttgttc agcaactgca attataaagt attctcaaaa actgatagaa gaaggagaaa
    66301 agagtaggat tttagatttg gcagagggaa atttagaaaa tgtaaatgca aagatggtgt
    66361 ttgatgcata tagagaaaat gatttagtgg caattaaagt aataaataga tttaaagagt
    66421 atttagcaaa aacttttgca aacacaataa attctttaga cccagaaatt atatctatag
    66481 gaggaggcat ttctaaatct agcgatataa tacttgatgg aatagaagat ttggtaagaa
    66541 aatttgtatt atacaaaaca gaagatatag ctacaattac atgtgcaact ttaggttcag
    66601 acgcaggaat tataggagca gcttttttat aatgtaaatg aactgcttat tggaggcgtg
    66661 atgatatatg ggtaaaacaa atgctagaag aacgcttttt ttgatagcaa taggttcagg
    66721 aactatgctg aatcctctta attcttctat gatttcactt gctttacata gtatacaaaa
    66781 tgattttcat attagtttta caactgtatc ttggattgtt tcagcatttt acctagctag
    66841 tgctattgca caaccagttt caggtaagat aggagattta ataggtagaa aggtcttatt
    66901 tttgagtggt ttgatgcttg taattttatc agcatccata gtaccacttg ttcaatcatt
    66961 ctttatattg atttttataa gagtaattca agcaattgga acaagtaccc tatatccatc
    67021 tggagttgct cttatacaaa ataatataaa agaaagacaa tcttctgcat tagcagttct
    67081 aaccattttt gcttcaacta cagcaggatt aggtccgaca cttggaggat tattgttgga
    67141 cttaggagga tggcatgcta tatttcttgt aaatatacct gttgttttgg tttctatatg
    67201 cttagggtat tttttattcc caaaagaagt aaaagaaaag aaatctataa aagaaacttt
    67261 aaaaaatgtt ttgtcaagat tagatattat tggcatactt ctattttcaa ttgcaatgat
    67321 ttttatatta ctatttttgc tatctatgaa ggagtctttt aacttggaac aacttgtatt
    67381 tggtataata ctgatgtgtc tttttatttg gcatgaattg agaacaaaat tgccatttat
    67441 agatattaag ctttttgtaa gtaatcctaa attgtcaaaa gtttacttgc aatttattat
    67501 attaaatttc tttaattata ttttgttttt tggtcttcct agttattttc aagatgcctt
    67561 acattatagt gcaaagtcga ctggattatt tatgctattt atgtctggta taggtatatt
    67621 tatatctcca ttaactggaa aatggataga taaatctgga actagatttc ctcttgttac
    67681 atcatcaatc tttatgttta ttagtgcagt acttctttca gtagttttta tccatatacc
    67741 tgtaatagga aagggtatta tattatcatt agcaggtatt agttatggag ttggtaatgt
    67801 agccctgcaa tcctctatgt ttgaagaaag tcctcgtgac agtataggga cagcttctgg
    67861 tctgtttcaa actagtcgtt atttaggttc tattttagca actgttttac ttggaatggt
    67921 atttgaagta aatataacat cagaacaatt tcagatatta ggttatgtta tggtggtctt
    67981 aggtacaata agttttttat taaattttat attaaagaaa gaattaagaa aagtagaata
    68041 gtggatttat ggatttaata agtctaataa ctgataagtt taaaaatatt gtttgtaaaa
    68101 cataactggt ttgatattta ttaattctaa gttttgaagc atagagtact cgataagtat
    68161 acaatatttt gaattaaaat taagcagaaa tttgaactag tctttcaaat ctctgcttaa
    68221 tttagtagtt aaattttttt atagagaaaa taagatttga cacttagata aaaaatcatt
    68281 gcattttcaa aattctttaa atcaaaccca agtatctcat taatcttttc caatctatat
    68341 actagcgtgt ttctatgtaa aaacatacta gtagatgtct tagaaatatt taaatcatta
    68401 tttataaatt ttattcctgt atatagaagt tcttcgtcaa tagatttaat cttattaaaa
    68461 tctattaatt tattgagtat attatcctca ttaattaaat ctaaagtttt atatctaata
    68521 aagtcaaaca aatttaaaaa cttattttca gcgttgtctt ttataatatg aggtagtaaa
    68581 tcagaacata actgtaatct aaaatcaaaa tcagctttac tatctaattc accaagataa
    68641 aaaatataag tactttgata agtttcagtt tcaattatat tttgtgtagt tacattaata
    68701 tctaagttat atttagaatt tactataaaa aaaccattgt gttgtattat atttatatct
    68761 tcaaataaat tataaaaaat at
//
LOCUS       DAYAOO010000009        67614 bp    DNA     linear   BCT 12-OCT-2024
DEFINITION  TPA_asm: Clostridioides difficile isolate ST8-SSI-h139-18
            SAMN40601845-rid21577343.denovo.009, whole genome shotgun sequence.
ACCESSION   DAYAOO010000009 DAYAOO010000000
VERSION     DAYAOO010000009.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN40601845
            Sequence Read Archive: SRR28438827
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 67614)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 67614)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-MAY-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-MAY-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002157583.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002157583.1
            Genome Coverage       :: 163x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/11/2024 16:19:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 4,038
            CDSs (total)                      :: 3,963
            Genes (coding)                    :: 3,930
            CDSs (with protein)               :: 3,930
            Genes (RNA)                       :: 75
            rRNAs                             :: 6, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 60
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 33
            CDSs (without protein)            :: 33
            Pseudo Genes (ambiguous residues) :: 0 of 33
            Pseudo Genes (frameshifted)       :: 7 of 33
            Pseudo Genes (incomplete)         :: 25 of 33
            Pseudo Genes (internal stop)      :: 11 of 33
            Pseudo Genes (multiple problems)  :: 8 of 33
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..67614
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN40601845-rid21577343.denovo.009"
                     /isolate="ST8-SSI-h139-18"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Denmark"
                     /collection_date="2018"
                     /collected_by="Statens Serum Institute"
     gene            256..507
                     /locus_tag="ACGI5H_000660"
     CDS             256..507
                     /locus_tag="ACGI5H_000660"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433976.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_process: GO:0065007 - biological regulation [Evidence
                     IEA];
                     GO_process: GO:0065009 - regulation of molecular function
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TM1266 family iron-only hydrogenase system
                     putative regulator"
                     /protein_id="HFG9696389.1"
                     /translation="MKKVAVISAILEEPKECQFKFNEVVSGFKGIIKGRMGIPCEEEG
                     VSIVCIAVVGEMDTINSLTGKLGNIPHVSVKTSISKKEV"
     gene            522..1730
                     /gene="hydF"
                     /locus_tag="ACGI5H_000661"
     CDS             522..1730
                     /gene="hydF"
                     /locus_tag="ACGI5H_000661"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729114.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005525 - GTP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="[FeFe] hydrogenase H-cluster maturation GTPase
                     HydF"
                     /protein_id="HFG9696390.1"
                     /translation="MSLNSTPQSVRVHIGLFGKRNAGKSSIINAITNQSAAIVSDIAG
                     TTTDPVFRPMEILPIGPCVLIDTAGLDDVGELGELRIGKSLDVLEKTDIALLVVDCQI
                     GISQEDLSLIEKFNDKNIPHILILNKIDTIKNQSEILNLTKNKVKCPVVSVSSTDKIG
                     IENLKNEIIKVLPKDSTEFKLVSDLIEPNDLVVLVVPIDKAAPKGRLILPQQQVIRDI
                     LDNGAISIVTKEDSLKETLSNLGKKPKLVITDSQVFPQVDKDTQKDIPLTSFSILFAR
                     QKGDLKELINGAYALENLKDGDKILMAEGCTHHRQTDDIGTVKIPNMIRKKTGKNITF
                     EFSSGVSFTEDINKYALVVHCGACMMNRAGMLSRIEKAKSFNVPIVNYGVLIAYVKGI
                     LERSLELFNY"
     gene            1766..2851
                     /gene="hydE"
                     /locus_tag="ACGI5H_000662"
     CDS             1766..2851
                     /gene="hydE"
                     /locus_tag="ACGI5H_000662"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424566.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0051539 - 4 iron, 4 sulfur cluster binding
                     [Evidence IEA];
                     GO_function: GO:1904047 - S-adenosyl-L-methionine binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="[FeFe] hydrogenase H-cluster radical SAM
                     maturase HydE"
                     /protein_id="HFG9696391.1"
                     /translation="MTKNKIKYFIDKLYSINSLSFDELLYLIENIDNEEYNFEQNLRN
                     YLYKQASDMRNKHYGNRVYLRGLIELTNYCKNNCYYCGIQSSNKNIIRYRLSLDEILE
                     CCDIGYKIGYRTFVLQGGEDAYFTDDKICEIVSSIKNKYEDCAITLSLGEKSYDSYKK
                     YFLCGADRYLLRHETATDSHYKKLHPPNIELRTRKECLKNLKEIGYQVGAGFMVESPF
                     QNNEDLVRDLLYLKELNPHMVGIGPFIPHHDTIFKDYKHGDLEKTLLMLSITRLLLPK
                     VLLPATTALASINPSGRNAGLLAGCNVIMPNLSPQEFRKQYSLYDNKAFTGQEACEYH
                     QSLEENIKSLGLEVDYSRGDNIEWRRL"
     gene            2852..4228
                     /gene="hydG"
                     /locus_tag="ACGI5H_000663"
     CDS             2852..4228
                     /gene="hydG"
                     /locus_tag="ACGI5H_000663"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430581.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0051539 - 4 iron, 4 sulfur cluster binding
                     [Evidence IEA];
                     GO_function: GO:1904047 - S-adenosyl-L-methionine binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="[FeFe] hydrogenase H-cluster radical SAM
                     maturase HydG"
                     /protein_id="HFG9696392.1"
                     /translation="MFINHELINSLLEDAKNSTSDDIEKVLDKADRREKLSYKDIATL
                     LEVEDKKQLDRLFSIAGQIKNEIYGNRVVLFAPLYVSNYCVNECVYCGFSKCNKFKRK
                     KLTMEEIKEEVKILEKMGHKRLALEAGEDPKNCDINYILDCLDAIYSTYNENGNIRRV
                     NVNIAATSVDEYKLLKEKGIGTYILFQETYHKPTFIKMHGQSIKNDYYYHLTAFDRAM
                     EAGVDDVGAGVLFGLSDPKFEVLGLMMHNEHLEEKFGVGFHTISFPRLKKAEGMSLED
                     FPHLVSDDMFKKIVAITRLAVPFTGIIMSTRETAEMRNELLKYGVSQISAGSLTGVGG
                     YKAYEDGDNTEQFEVGDHRSPVEVLKELITDGYIPSYCTACYRKGRTGDRFMSLAKSR
                     QIHNVCTPNALTTLNEFLIDYGDEELKIMGKKLIAEEIGKIEREDIRNIVSNNMTALE
                     RGERDLYL"
     gene            4319..4747
                     /locus_tag="ACGI5H_000664"
     CDS             4319..4747
                     /locus_tag="ACGI5H_000664"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430580.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9696393.1"
                     /translation="MKDNNNTNKTIQFGEKKASLENNIQKNKNIKLDNTHKVIPYPKN
                     RKKDDKKKGNKKKNTNTSKVNKNNYGHSFFNNKYKYKRKPYVIALYTVILILLAILII
                     TKLTDSTNKGNYSRNTVSDTHKNDIRNIVFNESNNFLICG"
     gene            complement(4822..6141)
                     /locus_tag="ACGI5H_000665"
     CDS             complement(4822..6141)
                     /locus_tag="ACGI5H_000665"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893495.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008483 - transaminase activity [Evidence
                     IEA];
                     GO_function: GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="aminotransferase class III-fold pyridoxal
                     phosphate-dependent enzyme"
                     /protein_id="HFG9696394.1"
                     /translation="MSEITSQMISTEEKKYVAKTQKIPYYPVAFKSGDGAMLYDYEGN
                     EYVDFLASAGSANVGHGNKEISQAVKEQMDDITQYTLAYFHSDPPVKLAEKLVEIAPG
                     DNDKKVLYSATGSACIDAAIKLARGYTGRTKIISMCESYHGSTYGAISISALSTNMRR
                     KMGPLLPEVYHFHYPDKNRTAKECLDEIEYAFAHYLPAEEVAAIFIEPIAGDAGIIVP
                     PVEWVQGLSKICKENGILLVSDEIQQGMGRTGKWFGIENFGVEADLIVLGKSVGGGLP
                     LGAVVGRTEIMQSLDAPAHLFTLAGNTTVCVAALKSIEIIEKENLLQKSIEMGDYIKA
                     GFEKLKEKYDIIGEIRGIGLSIGVDIVKGKGSNEKHPDATAKICYRCIQTGLIMIFLG
                     QSTLRVQPPLVITKEQVDKAMNIIDSAIDDYLNGRIGDEVYEVTQGW"
     gene            complement(6433..7218)
                     /locus_tag="ACGI5H_000666"
     CDS             complement(6433..7218)
                     /locus_tag="ACGI5H_000666"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433968.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9696395.1"
                     /translation="MEIIKYILYFFIYSFLGWTVESIGCSIASKRIINRGFLNGPICP
                     VYGFGAVIVISLLGRFNNVVIVFLLGMILTTILEYFTGFILETLFHAKWWDYSDRKFN
                     IKGRVCLKNAIYFGVMSVLIIRFIHPFIKYFVSIIPYRILISMAIITTLWTILDLIVT
                     IITLKKLDIKLNLLDDIITDLNDINVKLDKFDRGEIQALFKTINNDELEVREKINKIN
                     SKLDRIESNIILQKRVIKAFPHIKHKKQQEQLEHFKKIINEKR"
     gene            complement(7333..8292)
                     /locus_tag="ACGI5H_000667"
     CDS             complement(7333..8292)
                     /locus_tag="ACGI5H_000667"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897306.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VanZ family protein"
                     /protein_id="HFG9696396.1"
                     /translation="MIESKKSEKLLLSIIYIIFLVYILMIIRIILFRDVPIYAIFKGT
                     FRNVNLIPFYTIYQFIVDSNLDFMKATVNIIENIGIFIPMGIFLPIVCKNLNKKTIII
                     VIILVSLAFELTQYIFALGSSDIDDVILNSLGGIIGINIYINMNKLFPNDINRFKAII
                     GTSLVLGVIGLGVISKNYHNLLTFKFRPDRKISKILIEENREIIKDINKDTVDIVGTF
                     ESFKKGIITIKAGSNNKVKRPENLIDSDGNIRIYLNENTKLVSYIITKESKMDIVKYE
                     EFDVKNLDLLRRYDTINVWIDKENQPKDKHGIMASKLLIGLYE"
     gene            complement(8450..8767)
                     /locus_tag="ACGI5H_000668"
     CDS             complement(8450..8767)
                     /locus_tag="ACGI5H_000668"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430572.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9696397.1"
                     /translation="MGVLKGMFYVFLFLDLVSIFCFFFNKGKIASNKIVFNAIGVLTF
                     VLCFMLFSYYPNNNLIGKFIASLFFIFGVAGVMLKEKNFLYARLLLTVVIVFSTLRLF
                     VIQ"
     gene            complement(8874..9377)
                     /locus_tag="ACGI5H_000669"
     CDS             complement(8874..9377)
                     /locus_tag="ACGI5H_000669"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893498.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetyltransferase family protein"
                     /protein_id="HFG9696398.1"
                     /translation="MEQQKDYIELYENEELIEIREARMDDLDTIAKFNYNLAKETEGK
                     ELDMDVLTKGVKALLLDERKGKYHVYTVFDKVVAQIMYTYEWSDWRNGNFLWIQSVYV
                     DKEYRRKGIFNYLFNYIKNICDKDENIVGMRLYVEKENINAKATYESLNMYECDYNMY
                     EYEVVHS"
     gene            complement(9429..10628)
                     /locus_tag="ACGI5H_000670"
     CDS             complement(9429..10628)
                     /locus_tag="ACGI5H_000670"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433961.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003676 - nucleic acid binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DHHA1 domain-containing protein"
                     /protein_id="HFG9696399.1"
                     /translation="MEKLYYTNQYIRDFTAEIIEIKEVENKYHVLLDKTAFFPGGGGQ
                     FGDLGKIENDDVINVYEDGKKIYHVLDKKPIKIHKVKCSIDWDRREDGMHQHFGQHVL
                     SGCFFKTFNANTTGFHLGNEYSTVDIEGNLEEDKIREIELFANEIIRQNIQVETLLPT
                     KKELKKIWLRRDLPNTDEEIRVIKIGDLDTNACCGVHPKSTGELRMIKIKKWEKHKSS
                     TRIEFLAGKRAVDEVLKRDIYLTKICRYLSCSEEDAINGIVNLNSKVEEALIKKRRLE
                     EVVSTYQVKEMIEKANKVGNISVIKKIYDDEDLKYVNKIANKIAEYENSIALLAVKFN
                     DKINLVFACSKNLKDINMGVLLKDAINLIDGKGGGSKVLAQGGGKNNGNLEATLDYAF
                     MKIEKTL"
     gene            complement(10888..11076)
                     /locus_tag="ACGI5H_000671"
     CDS             complement(10888..11076)
                     /locus_tag="ACGI5H_000671"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861476.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9696400.1"
                     /translation="MNYHTKEELVEALRVVSSSIINCGKGQKKFSEETSHHTRFKNII
                     EVMYISKSLIMDEISKRD"
     gene            11411..12379
                     /locus_tag="ACGI5H_000672"
     CDS             11411..12379
                     /locus_tag="ACGI5H_000672"
                     /EC_number="1.1.1.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861477.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0004459 - L-lactate dehydrogenase activity
                     [Evidence IEA];
                     GO_process: GO:0006096 - glycolytic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="L-lactate dehydrogenase"
                     /protein_id="HFG9696401.1"
                     /translation="MAIKPRKISIVGSGHVGSHCGFSLITQGVCDELFMIDIDESKSK
                     AQALDLADAVSYLPHKVHIEKGTFSDCKDSDIVVISVADSSEGPLRRQNTTRLDLLRP
                     TIGMIKSIVKPIVDSGFDGIFVVISNPVDVVTNYIWEKSGFPKNKVIGTGTALDSTRL
                     RRILSEETGIAQQSIQAYSMGEHGDSQMVPWSHVSIGGKPILDMIKDNPSTYSNLDLP
                     SIVEKNKKTGISIINGKDCTEFGIGTALVEIVKAILHNEKKVLPVSTLLEGQYNERNV
                     FAGVPCVIGKDGIEEIIEINMTEYEQNEFNKSCSVLREYIALSKTL"
     gene            complement(12496..13626)
                     /locus_tag="ACGI5H_000673"
     CDS             complement(12496..13626)
                     /locus_tag="ACGI5H_000673"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729111.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="XRE family transcriptional regulator"
                     /protein_id="HFG9696402.1"
                     /translation="MNLKDFNGKRLKSARIFRAKTIEQLSKETKINKKDLKAFEENKY
                     VPNIENTLKLSNILNFPKEYFYKNENINIVVEDSHFNPQSKLPRVEEISYREKIIIIH
                     KIYSFMENYIKFPKENLPNRKVMSDININDIESLAYKTREFWDLNSTPIVNMVSLLES
                     KGIIISGMNVDRKGATIFTQKQRISKESKYLISLGNDKKSASIRNYTLACELGYIISS
                     ELRIPSKQFSEDEYACAFLLPKESFLKDLTHPEDLDYYVELKKKWIVPISAMIFRAYN
                     LEKINYKKYNYLMNEMDKKGWLIEEPLDKMKGSSPTYLKRAVELLIENKIMSVNSIVS
                     SLEEFGINLYPEDLELLMGLKKGLLSQEVNKKSKVIKFDGKK"
     gene            complement(13779..14732)
                     /gene="msrA"
                     /locus_tag="ACGI5H_000674"
     CDS             complement(13779..14732)
                     /gene="msrA"
                     /locus_tag="ACGI5H_000674"
                     /EC_number="1.8.4.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893500.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008113 - peptide-methionine (S)-S-oxide
                     reductase activity [Evidence IEA];
                     GO_function: GO:0033744 -
                     L-methionine:thioredoxin-disulfide S-oxidoreductase
                     activity [Evidence IEA];
                     GO_process: GO:0006979 - response to oxidative stress
                     [Evidence IEA];
                     GO_process: GO:0030091 - protein repair [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="peptide-methionine (S)-S-oxide reductase MsrA"
                     /protein_id="HFG9696403.1"
                     /translation="MIKLATFSGGCFWCMVKPFDKYDGVIKVVSGYTGGHVENPTYQE
                     VCSGTTGHLEAIQITYDDDIISYDELLNIFWKQINPTDDGGQFGDRGTQYKTAIFYHD
                     EEQKNIALESREHLENSKIFDSKIVTDIIPATKFYEAEENHQDYYKKRPLNYNMYYKG
                     SGRYNFVKSHWDGNNINREELKKTLTPIQFEVTQNDMTEVPFENEYYDNNKEGIYVDI
                     VSGEVLFSSKDKFDSGCGWPSFSKPVIDKSIIERSDFSQGMYRVEVRSAKGNSHLGHV
                     FDDGPKELGGLRYCINSASLKFIPRENMEALGYGEYLKLFE"
     gene            complement(14856..15761)
                     /locus_tag="ACGI5H_000675"
     CDS             complement(14856..15761)
                     /locus_tag="ACGI5H_000675"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890334.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0006629 - lipid metabolic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="patatin-like phospholipase family protein"
                     /protein_id="HFG9696404.1"
                     /translation="MKNSNFNILAFDGGGLKGALSISILERIVKEYPNLLNNINMFGG
                     TSTGSLIALGLAYGVSPKEIKELYSIENSKYIFNKSYAEILRPKYENKNLKEVLLSIF
                     PEELELKDLNKLVMIPSFYIGNEENAWKPVFYNNMPNSFTKTSKVVDVAMASSAAPVF
                     FPTYNRHVDGGIIATDPSLACIIHAIDSGFKLKNTRLFSIGTGYVYNSIKADTTEWGA
                     IDWIINKEPDLPIISITLEGNSQMSQLFSQKLLGDNYYRLNPKMEKDVAMDDCDALEY
                     LMSLGENCDIKDAFGWIKKKSFYRN"
     gene            complement(16133..17725)
                     /gene="hcp"
                     /locus_tag="ACGI5H_000676"
                     /gene_synonym="priS"
     CDS             complement(16133..17725)
                     /gene="hcp"
                     /locus_tag="ACGI5H_000676"
                     /gene_synonym="priS"
                     /EC_number="1.7.99.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430549.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016661 - oxidoreductase activity, acting
                     on other nitrogenous compounds as donors [Evidence IEA];
                     GO_function: GO:0051536 - iron-sulfur cluster binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxylamine reductase"
                     /protein_id="HFG9696405.1"
                     /translation="MEKMFCFQCEQTAGGKGCTINGVCGKKGGTANLQDELTGVLIGL
                     SRATIGNKNRPTSETDKIMIEGLFTTITNVSFDDEAIKRQIEKTEVEKSKLVPRCSDC
                     STTCNRNDNYDMKDLWNDNEDIRSLKSLILFGLRGMAAYAYHAMVLGYTDKDVNEFFY
                     EGLIAVGGDLSIDELLGLVMKTGEINLKCMELLDRANTETYGTPEPTQVSMKIEKGPF
                     IVVTGHDLYDLHKLLEQTKDKGINIYTHGELLPAHAYPKLKEYKHLKGNFGTAWQNQQ
                     KEFDNIPAPILFTTNCLMPVKDSYRDRVFTTEVVAYPGMVHIDEDKDFSSVIEKALEL
                     GGYREDVHMTGINGGDTLTTGFARGTVSSVQDKVVDAVKSGAIRHFLLVGGCDGAKPG
                     RNYYTEFVKQAPKDTVILTLACGKYRFNDLDLGDIGGLPRLMDMGQCNDAYSAIKVAV
                     SLANAFECGVNDLPLSMVLSWYEQKAVCILLTLLHLGIKNIYIGPSLPAFLSKNVLDI
                     LVDKFALTPISTPEEDMKKILG"
     gene            complement(17785..18510)
                     /locus_tag="ACGI5H_000677"
     CDS             complement(17785..18510)
                     /locus_tag="ACGI5H_000677"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424588.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HFG9696406.1"
                     /translation="MMRKIIKIDEEKCNGCGLCVEACHEEAIGMVNGKAKLLRDDYCD
                     GLGDCLPTCPTNAISFEYREAAEYDEAAVKANMEAKKAQKKTLACGCPGSQSKSINRE
                     VSNSTSISNDIVEIKGSQLNQWPVQIKLVPTNASYLKNASFLIAADCTAYAYGNFHNK
                     FMKNKVTLIGCPKLDEVDYAEKLTEILKENDIKNIVVTRMEVPCCGGIVNAVKTALQN
                     SGKMIPWQIVTISVDGKIVDGEI"
     gene            18675..19391
                     /locus_tag="ACGI5H_000678"
     CDS             18675..19391
                     /locus_tag="ACGI5H_000678"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430545.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_function: GO:0030552 - cAMP binding [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Crp/Fnr family transcriptional regulator"
                     /protein_id="HFG9696407.1"
                     /translation="MQQGSDYLKKFLEKHIDLLKKIPLFEGIKSDELEEMLECLGVVD
                     KTYPKDSIIFSVGSEVTSIGIMLKGSAHIIKEDIEGNRNIVAELLPGDLFGEVFACTR
                     LHKSNVTVTTTSSCEVLFIKFKSVTGICSSACVFHNRLVENMLQLIAEKNILLHNKIE
                     LLSRKTTREKLLMYFSKQIEQTGSHQFTIPFSRNEMADFLCVDRSSMSRELGKMRDEG
                     LLSFNKNKFEIFYFQNKLDI"
     gene            complement(19516..20091)
                     /locus_tag="ACGI5H_000679"
     CDS             complement(19516..20091)
                     /locus_tag="ACGI5H_000679"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430543.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0009055 - electron transfer activity
                     [Evidence IEA];
                     GO_function: GO:0010181 - FMN binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="flavodoxin family protein"
                     /protein_id="HFG9696408.1"
                     /translation="MVKVLAFMGSPRKKGNVDTILDEIIKGVNDNNVEVKKYYLNDMN
                     IKGCQGCLYCRKVPTCAFKDDMIDIYEDIKSAEYIIIGSPVYICQVSAQTKLLLDRLY
                     PLTEINKSKHIPRFGQKKLIMVYTQAAPISFLFKKYFKYTAKHLKGMGLNHYKTIVVT
                     KAFERNSTKKNFKVLKKAYKLGMKIAIDING"
     gene            complement(20265..20687)
                     /locus_tag="ACGI5H_000680"
     CDS             complement(20265..20687)
                     /locus_tag="ACGI5H_000680"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433927.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4Fe-4S dicluster domain-containing protein"
                     /protein_id="HFG9696409.1"
                     /translation="MKSLFKFNKELCTACGACLLACIDQNDNNIDNGELFRHVFTIEE
                     GENIEYFSLACIHCNEPKCLGVCPKNCFKKEEGFIVLDNQNCIGCKLCEKACEYGALI
                     YGNDGKANKCNGCIERYKCGMDSPCVMVCPTGALKFNK"
     gene            complement(20701..22878)
                     /locus_tag="ACGI5H_000681"
     CDS             complement(20701..22878)
                     /locus_tag="ACGI5H_000681"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433925.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molybdopterin-dependent oxidoreductase"
                     /protein_id="HFG9696410.1"
                     /translation="MYNKYNNLYLLLGKENVNMDSYKQLKAKIPCKETGIEIKRTLCD
                     ICSPGVHCGIDAYVKDGKVIKIEGTKEHPMNKGLLCTKGLCNREYIYREDRIKTPLKR
                     IGKRGEGKFKPISWDEAYREIAEKLNRVKSEYGAKHVAFFTGYGKWYRPFLQRFASSF
                     GSPNYGTESSSCSTSAQMAGNVATGRNFTMQDMENAKTYLGWGFNPYYSKFLNSVNLI
                     KLKEKGLKFIIVDPRITPTTQKLADLHLRIKPGTDGALALGMANLFIQKDLIDREYIE
                     KHVHGFNEYKEYVKLFDLDTVSRITGVSKDNIVKAVEMLSQGPFCINESAAPIVHHQN
                     GFQNYRAMMSLSAITGNYDRIGGNIPKQDYFAGKIGGFQTLEKEFVKEVLPKNINERI
                     GGERFPLWNEMVTQFQAMDLPRQIEEKTPYEIRALFCHGINARMFPNSGRLFKALNSV
                     DFFVNIDLFMTDTSKYADILLPACTSFEREECKSYPGGYITYTKKVIDKLYDSKSDVE
                     ILSDLANAMNIDDDLLKAGYEASVRHMFKNTCVDVDKLKESDLPLKCKDFKPYIVGSY
                     TREGYDTSTSRFELKSTIIEKYKDFGLDALPTYRGFNDNIDDEYTHLLTSGARISNAL
                     HSRLHDIKLSRILKNEANCDISSLDAKELGVISGDYIKITTKIGSLDVKVNVTDRVLY
                     KNIHMYHGYREADINSIICDNFDPYSGFPAYRSCKCKIEKMNR"
     gene            23159..26338
                     /locus_tag="ACGI5H_000682"
     CDS             23159..26338
                     /locus_tag="ACGI5H_000682"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433922.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SNF2 helicase associated domain-containing
                     protein"
                     /protein_id="HFG9696411.1"
                     /translation="MKIDMIYKLIRRNTEPSRWSRGVKYYTNQLVDYIDIDIDDLQNN
                     LLTFRGGVNSEDNYSFYFNSITIDIKHFKIIENDCSCADCQSKGKSIFICKHIVAIVI
                     KSLKQIKNKKDVPPILIDILGADKDKLSNTNSKTSLDLSKQLLSLLDNTKRERVNLDV
                     LINVDSNKAIAEFKIGINKMYILKNITEFAYSKLNGYELDFGKKFTYNPNTHYFADED
                     EKLVDIIEEYGTNLSYNFSSSHSKKFMEINASSLKQFLNAIKYKDFTLIFSKEEYHPK
                     ILNDTLPVRFDFKNIEDKIVLYSKDSLPVPLTKKNDVLLYDGNIYLLSHKKAHDYSKI
                     YQILSKTKELKFDKEDSKDVLGLLVPRLKSISQEVHLDDNIKNNITKDFKSEFYFDMI
                     DGNICCDVKYIYDDEDKKFVLPNIQKEATIENKLTSSQFTKENNHYVFKGTDHDLFTF
                     LDLQLESLKEFGDIYYSEKFKLKKIYNASSIQASINQTNQNYLEFNFNISDINPKEYK
                     DILKAFQEKRTFYKLKDGNFIDLSERETKDFFELVENLDIMDKSKNNKIHKNKALYIN
                     DVIRSKNLKFIDGKKELDSICEKFRNFDSINLEIPANLNANLRDYQINGLNWFKVLDY
                     YKFGGILADEMGLGKTIQTIAFLLSLSNKKSLIVTPTSLIYNWKNEFEKFAPDIKVLL
                     IHGNKRDREKCFMELENFDVILTTYGTLRNDLDKYSEIKFDYCILDEAQNIKNPVALV
                     TESVKSINAENKFALTGTPMENNLLELWSIFDFIMPGYLYSKAKFQELFINKEDNVKN
                     LKKLIKPFILRRSKKQVMKELPDKIEKNFFVELNKEQKKIYSVYSKDIQDKMKDKNLK
                     KDKIVIFSYLTKLRQLCLDPSIVVKDYNKKSSKIETCLEILRDSINENHKILLFSQFT
                     SVLKNISKELDKYKIKYHYIDGKTNAKERLELVDEFNNSMDKKVFLISLKAGGTGLNL
                     TSADMVIHFDPWWNPSVENQASDRAHRFGQKNSVQVIKLIAKGTIEEKIIKLQESKKE
                     LINQFINGELSNEGVLKSLSDEEIINLFN"
     gene            complement(26623..27387)
                     /locus_tag="ACGI5H_000683"
     CDS             complement(26623..27387)
                     /locus_tag="ACGI5H_000683"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729104.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HFG9696412.1"
                     /translation="MAYFNYNDKQCYYNEIGDGTPLLFLHGNTASSKMFNDIINFYKD
                     EYKVILIDFVGHGKSQMVDKFSADLWFDEAMQVICFLEAMNYKKVNIIGSSGGALVAL
                     NVALERPDLVNKVIADSFEGEVPLESFVQNVKIEREASKQDDGAKAFYIYNQGENWEK
                     VVDNDTEAIFEHYKTIGKFFHKPLETMQPEVLLTGSREDEFVSLISSDFFENTFSLLL
                     EKIKNGKMYLFDKGGHPAILSNGLDFSNVAKKFLEE"
     gene            complement(27543..27776)
                     /locus_tag="ACGI5H_000684"
     CDS             complement(27543..27776)
                     /locus_tag="ACGI5H_000684"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903070.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9696413.1"
                     /translation="MKAEDMKRKVSPIDLERILVTGGVIKHEDSIWLLDFWGNKDIAG
                     ILLMPPTRHVILHLNDCCKWKEYFRTKKKFYRS"
     gene            complement(27850..29343)
                     /locus_tag="ACGI5H_000685"
     CDS             complement(27850..29343)
                     /locus_tag="ACGI5H_000685"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433912.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003676 - nucleic acid binding [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HFG9696414.1"
                     /translation="MKYTFEKFKLNEKILKSLKSLGYNIPSRVQREVIPKLLKGQNLV
                     VRSKTGSGKTASFAIPLCENINVDYNNIQALIVVPTRELALQVKDEISDIGRLKKVRC
                     SAIFGKQSIKDQIAELKQRVHIVVATPGRILDHINRGSIKLENVKYLVIDEADKMFNK
                     GFVEQMEKILLNLPKEKIVSLFSATIDEEIKYICEKYMLDYSVINIEENESDTNQKTR
                     QIDDKIIKANGREKYILLKELIYSENPKSVIIFCNTKEKVSKLYNKMSKEGFLIRELH
                     ADLSQERRIFVIKDFKNQKFNILVSSDVASRGIHIDDISLVINYDVPQDKENYIHRIG
                     RTGRKGNSGKAITIVTEKDEKYIENIETYIGYKINELKDIEKSRITHGKVLFEEYSKG
                     ILKKVSKRKKVDKNSYKSKDIKLNIESEVVKLYLNAGKKKKIRVLDIVGAFSNIKGIT
                     NDDIGVIEVQDLCSYVDILNYKGDLILKKYKEIPIKKKMVKVKRDIR"
     gene            complement(29671..30213)
                     /locus_tag="ACGI5H_000686"
     CDS             complement(29671..30213)
                     /locus_tag="ACGI5H_000686"
                     /EC_number="3.5.1.28"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424618.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008745 - N-acetylmuramoyl-L-alanine
                     amidase activity [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase"
                     /protein_id="HFG9696415.1"
                     /translation="MKICITVGHSILKGGKSTGVNGIVDEYNYNKKLAPMLAEMLISQ
                     GNTVDVIICPERHFMSEREEFFYRVPKVNSGKYDLLVELHLNKADGTQCGTEVLYYGT
                     EGLEYAKRVSNRLGELFENRGAKKRENLYILRNTNPVAIQIESFFCDNVNDCNKANES
                     GYDYIARLITEGILNKDINM"
     gene            complement(30503..31450)
                     /locus_tag="ACGI5H_000687"
     CDS             complement(30503..31450)
                     /locus_tag="ACGI5H_000687"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890361.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9696416.1"
                     /translation="MRITKTTFNDVFSNDANGSIIKVEKYVDKKCASVFEILTYTIIV
                     TNTSRYKTGNIFFKDYISKYIEFINNTVKVNGIIKRGLDPQQGFYIGRIDASCKKIIS
                     FKSVVLPNSAHRIIKNSANIYYYYKCNLDKFPTRISIESNRVYTNVNKIVFKQLNISN
                     TLKAPKNLRDILKVNVNSKIFDVKPMKNLINKGSNLKLCNLIVFGYIEVEIDYSCKNR
                     SNFKTVNKSNDIKKDKYYKNDIQNNNENINDCKKQISFGDNKVKKITKTFGFSCFICS
                     PVGIIYEDMKNINIKIEHTSINELNPEELFVNTSLLLYY"
     gene            complement(31478..31969)
                     /locus_tag="ACGI5H_000688"
     CDS             complement(31478..31969)
                     /locus_tag="ACGI5H_000688"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861486.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9696417.1"
                     /translation="MYENNKVIYNLERCEKLEKTLYLSQFNTYKNFKLASKKTVINSL
                     ETYVYNMNINNISLVDTIECISLEDEQLTGKKLILVGDIDIDAILDYAGNKRNRNSSK
                     KNTFKLKIPFSTFIQMPRKIENKDKINLKYLIQDITSSILDDNLFISVTAIISYENSS
                     KIE"
     gene            complement(32412..33305)
                     /locus_tag="ACGI5H_000689"
     CDS             complement(32412..33305)
                     /locus_tag="ACGI5H_000689"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430511.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004040 - amidase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glucosaminidase domain-containing protein"
                     /protein_id="HFG9696418.1"
                     /translation="MKNKKFIVIILIISILIGVLVKEYSSREIKKDDINVSKYIKYAD
                     LASKNNAQVNWKYVASIVAVLNKNNLKNVKDSQIQEVSDLFVKNFSKNNKINKLSDIL
                     DELEFSNRQKRLVDNYIDNLKDYGIKPERLKSDTKYMKFIDEIKTEAIQNYKDYKILP
                     SITIAQAIIESSWGKSTLAKQYNNLFGIKADAYWKGKSVTLETKEHLDTIIDDKFRIY
                     DDKNESIKDHAKFLATNKRYKNNGVFDAKTYIYQAKALEKAGYSTAKDENGNSIYAAR
                     LIELIQQYNLQLIDSEIQSEM"
     gene            complement(33530..35815)
                     /locus_tag="ACGI5H_000690"
     CDS             complement(33530..35815)
                     /locus_tag="ACGI5H_000690"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861487.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 65 protein"
                     /protein_id="HFG9696419.1"
                     /translation="MKCLFSNVDEWKIIQDKIEIKENRLAESIMSIGNGYMGMRGNYE
                     ENYSGDTHKGSYIAGVWFPDKTRVGWWKNGYPEYFGKIPNSVNYIGVRIFIDDVELDL
                     AKCKVEDFHRELDMKNGILNRRFIVNINDKKFEVRVTRFLSISVKELAVIKYSIKSLN
                     SNTKIKFVPYLDSNIKNEDSNYEEKFWNGISSSSLEYKGSILSRTKENAFNTPVFTVG
                     SMMYIKTNGDVEAVSHESDYNYCENSITMDVLKNEVASIEKYVSITSTRDYKESELLR
                     KCEDILNRELSKSYDDILNEHIKLWNKRWESADVKINGDKSSQQGIRYNLFQLFSTYY
                     GEDSRLNIGPKGFTGEKYGGATYWDTEAFCVPVYLGVADKEVTRNLLEYRYNQLEQAK
                     DNAKKLGLKGALYPMVTFDGVECHNEWEITFEEIHRNGSIVYAIYNYTNYTGDYKYIK
                     EKGIDVIIEIARFWASRVHLSTKKDLYMIHGVTGPNEYENNINNNWYTNYIAKWCLDY
                     AVENILRLEKECNECIDRNNVTREEVEFWKIISNKMYLLYDEELQIIIQNDNFLDKEF
                     VEVKDLPKENFPLNQNWSWDKILRSCFIKQADVLQGIYYFGNRFTKEEKKRNFDFYEK
                     YTVHESSLSSSIYSIIASEIDNLEKAYELYSRTARLDLDNYNNDTNDGLHITSMSGSW
                     LSIVHGFAGMRTWNETLSFDPKLPKEWKNYSFNINYRDNIINVDVCSDLIKIENLKGK
                     PIKIIVYGKKYILEKCIKIDK"
     gene            complement(35812..36492)
                     /gene="pgmB"
                     /locus_tag="ACGI5H_000691"
     CDS             complement(35812..36492)
                     /gene="pgmB"
                     /locus_tag="ACGI5H_000691"
                     /EC_number="5.4.2.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430507.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000287 - magnesium ion binding [Evidence
                     IEA];
                     GO_function: GO:0008801 - beta-phosphoglucomutase activity
                     [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="beta-phosphoglucomutase"
                     /protein_id="HFG9696420.1"
                     /translation="MIEAFIFDLDGVITDTAYYHYMAWRKLAHKVGIDIDTKFNESLK
                     GISRMESLDRILEFGNKKYSFSEEEKVRMAEEKNNYYVSLIDEITSNDILPGIESLLI
                     DVKSNNIKIGLSSASKNAINVLNHLGISDKFDFIADAGKCKNNKPHPEIFLMSAKGLN
                     VNPQNCIGIEDASAGIDAINSANMFSVGVGNYENLKKANLVVDSTNQLKFEYIQEKYN
                     EYIVRRII"
     gene            complement(36716..38599)
                     /locus_tag="ACGI5H_000692"
     CDS             complement(36716..38599)
                     /locus_tag="ACGI5H_000692"
                     /EC_number="3.2.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430505.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004553 - hydrolase activity, hydrolyzing
                     O-glycosyl compounds [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 13 protein"
                     /protein_id="HFG9696421.1"
                     /translation="MSNKNKENITLSNQIKGTIQNSLTKEAILHIPMSNYAYGYDRET
                     LHIRLRTKKNEAKRVILRIGDQYVWDKGGAGGGNLNASGVGWSGGTNIVMSKEVETEL
                     FDYWIAKCKPLNKRSRYGFIIEGQEEKLLFTEKRIIELGNENDEKELCEIGNFFGYPY
                     LNYIDIPKVPNWVKDTVWYQIFPDRFANGDPSINPEGVDKWGAIPTRDNFTGGDLQGV
                     IEHLDYLSDLGINGIYFCPITIGKTNHRYDTVDYMEVDPTLGDKETLKKLIEEAHKRN
                     IKIMLDAVFNHIGYYSKQWQDVVQNKENSRYKNWFYIKDMSKIDTPIEQIDEKNIPYE
                     TFGCEKYMPKLNTENSEVIKYLLDVGKYWIQEFDIDAWRLDVSNEVDHVFWRKFREEV
                     KKVKPDIYILGEIWHGSLPWLMGDQFDSVMNYLMSEAMKKFFCTDEINAEEFKYMIND
                     VMVSYPIQVSEVIFNLLGSHDTTRILTYANGNIDRFKLAYMFMFVQTGCPCIYYGDEI
                     GMEGELSSISEGQRKCMEWNEEKWNKDIFDFMKKIIRLRKENKELRSISNEWVLADKE
                     NGTIILKKESISIIINNSSKNIILTLPDYLANKKVKDLYEEEIVDLKEELMLEKYKFI
                     ILK"
     gene            complement(38857..39678)
                     /locus_tag="ACGI5H_000693"
     CDS             complement(38857..39678)
                     /locus_tag="ACGI5H_000693"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433897.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004401 - histidinol-phosphatase activity
                     [Evidence IEA];
                     GO_process: GO:0000105 - L-histidine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="histidinol-phosphatase HisJ family protein"
                     /protein_id="HFG9696422.1"
                     /translation="MNLIDNHIHTNFSSDGKDSMEDTIKKAISIGVRYLTFTDHLEHD
                     EDRGFCINYNDYVPVFNKFKEKYKKDIELLLGVEVGYRKHLKNEIEEIINSNPFDFVL
                     CSTHTIDNVPVPSKAYFKGLSKEDAYYKYFNSILETNREFGDYNIYGHLDYISRYGIY
                     SDNRVIYNDFKDVIDEVLKSIINNGSGIELNTSGYRYGLNAIHPNEDILKRYKELGGF
                     IVTVGSDSHRVEDICKDFDVAYDMLKYLDFKYVSLFKERETYFVNIEKVKSNNIA"
     gene            complement(39869..40222)
                     /locus_tag="ACGI5H_000694"
     CDS             complement(39869..40222)
                     /locus_tag="ACGI5H_000694"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423420.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9696423.1"
                     /translation="MKKSNIFSIIFPTVIMVLMFLTFATDIFNIPDIQSKSIFVVGMV
                     LIFPISFLIQGIICVLNKTNWILSLIVSLVTYIVLMYIFLNDSAYIYVLLYTAFYMIG
                     HITAKLYYKIKTFKN"
     gene            complement(40264..41706)
                     /locus_tag="ACGI5H_000695"
     CDS             complement(40264..41706)
                     /locus_tag="ACGI5H_000695"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423418.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall-binding repeat-containing protein"
                     /protein_id="HFG9696424.1"
                     /translation="MRTIRRVLALGLTLAIFLINVPNVDALTSDTIKGNNIYETAGLI
                     ADKKSYDTAIMVNMDNSIADGLSASGLAGAVDAPILLAQKNKIPNETKQRLKNVKKIY
                     IIGKELSISKSVETELKNTGAQVTRLGGDDRIKTSYSVAKEVNGIKKVDEVILTNAYK
                     GEADTISAAPVSVRDIAPIVLTDGKSVPFSTSNVKTYAVGGSISMSTSLVNKTNAKRL
                     GGSDRYDTNKKVIKEFYPDASEFYLSDGYDLVNALTGSTIAKENPIVLVSESSDKSIL
                     AGADKITRLGSISDSVYNKCVSAAQNNGDSSTKGESPMKNETSILGQPTASLEACLKW
                     AKSKKANDLFIELIPILYDTAVQEGVNPVLAVAQSAKETGFCNFGGVLDASFKNPCGL
                     KTSVGGSDTDKNAHSRFDTWEEGILAQIQHLCLYAGQDGYPLSNPVDPRHEKSLFGKA
                     KTVESLSNNWAGGQYGQDLVRMMGEIEATK"
     gene            42382..43593
                     /locus_tag="ACGI5H_000696"
     CDS             42382..43593
                     /locus_tag="ACGI5H_000696"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890368.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="HFG9696425.1"
                     /translation="MSNKQGSNIKDVKIKNKLIILKLLSTNTPMSRVDLAKSTGLTKM
                     TLSNLVTELINENMIREIESSTLNAHSSGRKPILLDISNISPCICGILIRRNICKVII
                     SDLKGNIVKQLSETYPKFLSNDVLKDIIKRMFTKIMKINKRDIIGIGISSIGPVDDIN
                     GTILNPPDFGNVSNLNIVDFIKEMSDLPIFLINDANSGALAEKMYGLGKNISNYIYLH
                     IMNGIGAGLVLENKLHTGNLGQSGEIGHTSINFSGPLCSCGNNGCLDYYTSVSNLIKR
                     IESLSHIYPNSPLINCKDFSLVKLIDEANNKDSLAMFLLDEFCTYVSYALVNTLTLID
                     CSSIIIGYDFNIPGTFIENTLLKKLTASASFSKYKKISVRHSNFGANAPLIGSIAIVS
                     YNFFNGSINFY"
     gene            43685..44200
                     /locus_tag="ACGI5H_000697"
     CDS             43685..44200
                     /locus_tag="ACGI5H_000697"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423414.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ferritin"
                     /protein_id="HFG9696426.1"
                     /translation="MISAKMEKLLNEQINHELYSAYLYLSMSSYLEAEGLKGFSNWFY
                     VQYKEETDHAMFFYKYLHNVGGKVQLDAIPMPDSDFTSAMDILERTLAHEKKVTALIN
                     NLAAVANSESDFRTSQFLLWFISEQAEEETNCEDNIKRVKLAGEGGLFFVDQEFANRT
                     YAAPTNPPVTI"
     gene            complement(44467..46566)
                     /locus_tag="ACGI5H_000698"
     CDS             complement(44467..46566)
                     /locus_tag="ACGI5H_000698"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423413.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetate--CoA ligase family protein"
                     /protein_id="HFG9696427.1"
                     /translation="MSLEKLIRPKSIAIVGVTDKLGFGRSAALSIVKSKETDRVYYVN
                     PKREELFGRKCYKTIQEVPEVVDCVVVCTPRNVVPSVLKDSGELGTKAAVVYASGFAE
                     EGTEEGTDLENQLIEISNTYDMKILGPNCMGLLNCIDKVNLWAGGSKWDLDTKKPGIG
                     IVGQSGFITAEIVSSDYFNISYGFSTGNGNIVTLEDAVDFLVDDDYASVIAIYLEGLK
                     NPQKFIDALKRAAQKRKPVIILKSGRSEKGAISAASHTGNLAGSSKAFESIFEKYGVI
                     SVENLEQFMCLAQAFSVLDGNLPANSNFAAINFSGGENTICADLAEENGVELAEISSE
                     TKEEMEKYLPGFATPKNPLDATTALFHEKDMIVGLLHTFEKDDSVGFTMVGANIRDEE
                     NEMHETLCKAVSEAREQGLKKPVFAVPTLEGNRYLDYRTRLEDNQVPIMSSVGTTFTC
                     FNKMAKFIDYDYSKRTLEFKAVKKRESNNVVALSELDSKIEMKKYGVPVPGQGNAKSI
                     DELDEILKYIKYPVVLKINSSEILHKSDVGGVKIGIKNRDEAVDAYNEILTNVKKAKP
                     DANIDGILVQEMVESGIEIIIGITNDDQFGPMLLVGLGGVFVEVFKDTTLYPLPINHD
                     EAIMMLKKLKSFKLLNGYRGSEPCDIDALADMMVKLGKYAYENKDEVKEIDLNPVFVY
                     PKGKGVCAVDALIVKYK"
     gene            complement(46690..47229)
                     /locus_tag="ACGI5H_000699"
     CDS             complement(46690..47229)
                     /locus_tag="ACGI5H_000699"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433888.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016903 - oxidoreductase activity, acting
                     on the aldehyde or oxo group of donors [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="2-oxoacid:acceptor oxidoreductase family
                     protein"
                     /protein_id="HFG9696428.1"
                     /translation="MEKELVFAGFGGQGVLTLGLIVAESALELGKQVTWMPAYGPTMR
                     GGKAYSVVKFSDESIGGPDMEEIDVLVAMNKPSLDYINLVKEGGTVVINTSAIDENVT
                     LREDISVVKINCQELAQKVNNPKAANIVVLGALIAKTGLFEKELALKTMCDFFEEKGK
                     GKFNVQNEAAFMEGYNNAI"
     gene            complement(47232..47972)
                     /locus_tag="ACGI5H_000700"
     CDS             complement(47232..47972)
                     /locus_tag="ACGI5H_000700"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433887.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003824 - catalytic activity [Evidence
                     IEA];
                     GO_function: GO:0030976 - thiamine pyrophosphate binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="thiamine pyrophosphate-dependent enzyme"
                     /protein_id="HFG9696429.1"
                     /translation="MATEKLTPSVVSIPNKFCPGCGHGIVNRIIAEVIEEHGYEKNHV
                     LTLGVGCVCNMNFSWNGDKMQTAHGRASSTAIGVKVALPDTLVMTYQGDGDAYVIGLS
                     ETLNTAYRNHNVTVFVINNNNFAMTGGQMSWTTMPGQVTTTSVNGRDIKTTGSPLKVP
                     EMVANFFDVAYVARGSVHSPKEIINLKKYIKNAIEAQLNGEGYSLVEILAPCPTNWGV
                     SLEKSIKWMEEEIVPYYALGEFKQRDGE"
     gene            complement(47974..49023)
                     /gene="vorB"
                     /locus_tag="ACGI5H_000701"
     CDS             complement(47974..49023)
                     /gene="vorB"
                     /locus_tag="ACGI5H_000701"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433885.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-methyl-2-oxobutanoate dehydrogenase subunit
                     VorB"
                     /protein_id="HFG9696430.1"
                     /translation="MKKMWKGNHAIAEAALRGGCEFYAGYPITPQTEVMEFLSHRMSE
                     LGRTFIQSENEMAAIYMVYGAYASGMRSMTSSSGPGISLKQEGISYLCANHYPCVIVN
                     VQRWGPGLGSLDSAQTDYLRDTRGGGNGDYHLIVYAPNSIQETVDLMYNSFDVAEKYR
                     VPVEILTEAALGQMMEPVEFPEFKKREGDLGWTYDGSNRDHAKVADNQKPTFCMEKRM
                     RITENEQQWEDYQVEDAEYVFVAFGIPSRTTMNAVRRLREQGEKVGIIRPITVWPFPY
                     KAFEKVSKDVKGFISVESTDTGQLVEDVALASKKVCKENVPVYGLFSGNHIPKTLQVM
                     DTYSKIKSGEIKEVF"
     gene            complement(49040..49258)
                     /locus_tag="ACGI5H_000702"
     CDS             complement(49040..49258)
                     /locus_tag="ACGI5H_000702"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897359.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4Fe-4S binding protein"
                     /protein_id="HFG9696431.1"
                     /translation="MNLKINAERCKSCEYCVISCKKGALKISSKINKEGYAHVEVDES
                     KCILCGICYQVCPDNVFEIIKEEACQEA"
     gene            complement(49291..50394)
                     /gene="hisC"
                     /locus_tag="ACGI5H_000703"
     CDS             complement(49291..50394)
                     /gene="hisC"
                     /locus_tag="ACGI5H_000703"
                     /EC_number="2.6.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893521.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004400 - histidinol-phosphate
                     transaminase activity [Evidence IEA];
                     GO_process: GO:0000105 - L-histidine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="histidinol-phosphate transaminase"
                     /protein_id="HFG9696432.1"
                     /translation="MIEKLLRNTVKELHQYVPGEPIEKVKEKYGVKEIIKLASNENPL
                     GPSPKAIEAMIEMLKQGQLYPEPEANELRRKLAEKLDLKPENFIVANGADNVITLIGE
                     AFINRGDEVIYCNPTFPSYRTATIKNEGIPVEVPLTEDYKYDLQGILDKITDKTKLIC
                     VCNPNNPTGTIVDDKELEEFLKKVPENIITILDEAYIEFLTVPNYVDGLKYVRENYNV
                     IVTRTFSKIYGLAGLRVGYGIAKDEIIRTLFTVKEPFSANRVAISGATAALDDEEFIK
                     ETYELNRVGMAYFKEEFTKMGFDVVDSQSNFLYVDMKTDIPKLFEDLKKRGFVIRPSA
                     THARVSIGTMEENRKFVAVLKEILNIKGEPSIG"
     gene            complement(50497..51927)
                     /locus_tag="ACGI5H_000704"
     CDS             complement(50497..51927)
                     /locus_tag="ACGI5H_000704"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905807.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HFG9696433.1"
                     /translation="MSSQESKPKGNLISNFRDDMRDPKKRAIYTYSSSINLAYNFIGY
                     FVSTVTNIFLTDVAKLGVIMAGGMQIIQSFIKIAVAPITGTVFDKQPFKKGKYYPWLR
                     YAPAALALTYGIFFIVPLMKISPALLLPLMTALLLIASCAQQVVFTIIYAIYPVVAKT
                     PRDRVIGSTTTNIFKEVSKFLVGFSYPLLLVLFADVLGGEGMGYLGTYLFFAAGCLLV
                     FWFSSTEIIKSGAEEEVLQKEEKPKIKASEMAKALFTNVPLMMAFCLEFLICIRSIGL
                     GPLAPYYFKYVIEDERGLAVFLSIMPLVSVAFMFFAPVFIKICREQKLASIISFSICA
                     LCHLLVAWTPWGKTTLGVTMLLAIGGGFSNVVSIINLNFFAGSCDYGHWKSGKDLPGL
                     SMSLYPVAIQVGVLLATTIRTVLMNSMGYQADMVVTEAVKSGFINMISYSMAIPLIIA
                     VVIAILYPVSDKKLNQIREELNQRNA"
     gene            52585..53949
                     /locus_tag="ACGI5H_000705"
     CDS             52585..53949
                     /locus_tag="ACGI5H_000705"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897363.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sodium:solute symporter family protein"
                     /protein_id="HFG9696434.1"
                     /translation="MLLLIVTCAIYIWIGFYFSKKVKTASDFLIAGRNLPLPILAATI
                     AATSFGGGCLVGGVQWGAERGLWVGMYSTIGAALACFINAFFAGKLRSLSCDITPADY
                     IETRYGHSVFLRAYQSLVTPISILAIMGSQLISFGSVSTAFGIPYDIAVIIGVIVIII
                     YTYTSGMWGVAVSAFIQLAICIVFLPIVAYISLKLVGDNPLLMLQSMVKEPFFPGNKS
                     ISDFMYTVLPLVLGSIFSYESFLRYQCADNAKNAVKSSVIAGFILLFLAFPIGIIGAI
                     GGSLFPNISSVQVLPQMISTTLPPLISVLFLAAILAAIMSTADSLMTSMSAIISRDIY
                     NKLLHPNIEFNDLKNTLKYSQIASALTAIIGAIIALKFDSLLELLFWPAPLCTGVIFA
                     PFVIGLCWKGATKKGAIYAVIVSVILALLNMIGILTVFDRILVPIIGGSITIFIVSKF
                     SKKD"
     gene            53973..54626
                     /locus_tag="ACGI5H_000706"
     CDS             53973..54626
                     /locus_tag="ACGI5H_000706"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423398.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HFG9696435.1"
                     /translation="MSKSEKGKETKASIISAARELFFEQGYHKTTTRQIAERANINLG
                     LISYYFSSKSEIGAIIYEDIRNEMQSLIYNYHEEGTMMMFFLAMNADLCFLLKNEAYR
                     NFYLDIAYEEAILSYQRSVTEMVMKRYVNDKESIEHDELILSCIGILAMKPEIIRVYT
                     SHKYDISSQAVIKHFTKQFLINLGHSTDLCEEILEELSKYYIDIVDNFTPIITRVRT"
     gene            complement(54745..55527)
                     /locus_tag="ACGI5H_000707"
     CDS             complement(54745..55527)
                     /locus_tag="ACGI5H_000707"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890379.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HFG9696436.1"
                     /translation="MAFIECKFKSKYTGGETDIIVILPVANGKELFSGKEIYDFEGKF
                     KTLYLFHGLEDDQSSWIRYTNVEHYAKNKNIALVIPRVETSFYTDMAYGHQYFTFVSE
                     ELPKFVRAIFPLSDKREDNFVAGMSMGGYGALKLALSKPKEFSAVASFSGSPDMIHEL
                     ENQQIETNADILFHDFGRPEDARNSENDLLYILKNLKERNEDIPKIYQFCGDRDFLYK
                     NNQMFKKYADSLGVDVEYEECVGGHEWRLWNLWIKKFIDIIG"
     gene            complement(55644..56810)
                     /locus_tag="ACGI5H_000708"
     CDS             complement(55644..56810)
                     /locus_tag="ACGI5H_000708"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430484.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0015562 - efflux transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:1905887 - autoinducer AI-2 transmembrane
                     transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="AI-2E family transporter"
                     /protein_id="HFG9696437.1"
                     /translation="MKINWNTKYTTIAIYTFIIAASSIIFYLVSSQIDVFSNNLDAIF
                     TTLQPFIIGFAIAYLLNFILKFYEDRIFIKSEKLKKLKQSSKRGLGLLLTYATATLIL
                     YLFMHFVLPQVIESIVGLANDIPMYVNNATKLIDKLMTDLNLDEQYFNLAVDKWNEFV
                     TYIIKFVTDLIPILGSMLKNVASSIWNIVLGLIVSVYLLIDKEKFYGLSKKITYAVFT
                     EKQAARILELTHRSNYTFGRFLGGKILDSFIIGILTFVILTLVKMPYTLLISVIIGIT
                     NIIPFFGPLFGAIPSTLIVMFVSPIKAFWLLLIILIIQQIDGNIIGPKILGDSIGISA
                     FWILFSLLVAGKLLGFIGMVIGVPMFAVIYSIIKDIVESKLDKKGLPTDTSDYM"
     gene            complement(56949..58313)
                     /locus_tag="ACGI5H_000709"
     CDS             complement(56949..58313)
                     /locus_tag="ACGI5H_000709"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903082.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldehyde dehydrogenase"
                     /protein_id="HFG9696438.1"
                     /translation="MDIKELVKMQRKYYNTGKTRDISFRIEQLKKLKLVVSQNEEKIL
                     LALKKDLNKSDFEGFMTEVGMFYSELNFAIKNIRKWSKIKRVKSSMVNFPSISKVVPQ
                     PYGVTLIMSPWNYPFQLALIPLVWSLAAGNCVILKPSEYSVSTSSVVKDIVEDTFSKE
                     YVAVVQGSQEESEKLLLERFDYIFFTGSTNVGKIIMKSASEHLTPITLELGGKSPCII
                     LKDANIDLTAKRLTWGKLINAGQTCVAPDYVLVHEDRKNELIEKIKYYTNKYFGDNAC
                     NNEQFPKIINQRHFNRILSLIDKDKIVYGGNYNKETLKIEPTIVDNVNWDDNIMKEEI
                     FGPIFPILTYKDLDEVIQKIIQMPNPLALYIFTKNKYLENKLLEMIPAGGCCINDTVT
                     HIATNYLPFGGIGESGMGSYHGKAGFDTFTHYKSVLKKLNLDVPIRYAPYDNKLIKVL
                     KKIM"
     gene            complement(58625..59149)
                     /locus_tag="ACGI5H_000710"
     CDS             complement(58625..59149)
                     /locus_tag="ACGI5H_000710"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897366.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flavodoxin domain-containing protein"
                     /protein_id="HFG9696439.1"
                     /translation="MKNVVVIYKSKYGSTKKYAKWLSELLSCDIFETKNINIEKVMKY
                     DTIILGGGLYACNIAGISFLKKNYKELQKKNLVVFGVGAAPYDDEVIKKLREVNFKDE
                     LNKIPCFYCRGAWDETKMSFIDYTLCSFFKKSIAKKERQGLKPAEAPLLSGEAFDWCN
                     KENLTPILDYIREL"
     gene            complement(59199..59696)
                     /locus_tag="ACGI5H_000711"
     CDS             complement(59199..59696)
                     /locus_tag="ACGI5H_000711"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903083.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HFG9696440.1"
                     /translation="MDAESLMKKYMVDDDSRKQAIFASIFVMQNKLQTTCDKLDPELT
                     MKQWLLLAIADSVDETLTLTKLGELMGCSRQNVKKLAIALEKKGFIQIEQNEKDSRAI
                     CLVTKDRVQEYSKKVRGMQEKVLQLLFEDFTEKEVEQLFFGIMKLSIGIENVKNYVEN
                     NDVGE"
     gene            complement(59929..61200)
                     /gene="hflX"
                     /locus_tag="ACGI5H_000712"
     CDS             complement(59929..61200)
                     /gene="hflX"
                     /locus_tag="ACGI5H_000712"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890385.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005525 - GTP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GTPase HflX"
                     /protein_id="HFG9696441.1"
                     /translation="MAKKGITVGLNINNKSEDFNELMIELENLCSACDIDVVGSITQN
                     AKQVNRAFYIGTGKVEEILNLIKKENIEIVIFYNELSTSQLKNLEEKLNCEIIDRTAL
                     ILDIFAQRAKTREAKLQVEVASLKYMLPRLIGSNENLGRQSGGVGTKNRGSGEKKLEL
                     DRRRIEEKITSLNRELDDLKFQRETQRSMRRKSNLPNVALVGYTNAGKSSIMNKLVDI
                     FKNSEEKKVFEKNMLFATLETSVRNIVLANNKEFLLSDTVGFVSNLPHDLVKAFRSTL
                     EEACEADVLLHVIDISNPSYKSHIKVTEDTLKQIGADGIPMIHVYNKIDLIDVEVLDR
                     ILDSIDKEGIFVSVKKDINIDKMIKCICDSIFKDYVRCKFLIPYDKGHVVSYFNENTS
                     IINTEYREDGAILDVECSNIEYNKYKKYALE"
     gene            complement(61925..63757)
                     /locus_tag="ACGI5H_000713"
     CDS             complement(61925..63757)
                     /locus_tag="ACGI5H_000713"
                     /EC_number="7.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433862.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HFG9696442.1"
                     /translation="MSRMGRGPMGKSMGAGQKANDFKGTMRKLIAYLSKFKISIILVI
                     VFAIGSASFSIVGPKILGKATTKIFEGLVSKVSGGNVGIDFNAIGKILTFLLFLYLIS
                     ALFSFIQGFIMSGISQKVSYNLRKEISAKLDRLPMKYFDTKTHGEILSRITNDIDTLN
                     QSLNQSMTQLITSVTTMIGVLIMMLSISGIMTLVAVLILPISMFVISRIIKKSQKYFR
                     YQQEYLGNVNGQVEETYSGQTIVKAFNREDEVIEEFDKLNDSLYNSAWKSQFLSGIMQ
                     PLMMFIGNLGYVMVSILGGWLAIKKTIEVGDIQSFIQYVRNFTQPMTQIAQVANLLQS
                     TAAASERVFEFLEEEEEVQIVENAVSIDGLEGKIDFENVNFGYNPNKTIINDFSVNVK
                     PGQKVAIVGPTGAGKTTIVKLLMRFYDVNSGSILIDGHNIKDFNRSELREMFGMVLQD
                     TWLFSGSIMENIRYGKLNATDEEVIEAAKSAHVHRFIKTLPDGYKMKLNEEASNVSQG
                     QKQLLTIARAILADPKILILDEATSSVDTRTEVLIQKAMDNLMEGRTSFVIAHRLSTI
                     RDADMILVMNEGDIVEQGNHEELLKKGGFYANLYNSQFEEDEAM"
     gene            complement(63750..65996)
                     /locus_tag="ACGI5H_000714"
     CDS             complement(63750..65996)
                     /locus_tag="ACGI5H_000714"
                     /EC_number="7.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HFG9696443.1"
                     /translation="MFKLIKYLKKSALSIVIIVCLLVIQAVCDLSLPEYTSNIVNVGI
                     QQGGVENSVPSVIRESELNKITLFMDKSSKDKVLDNYTLLNKKDYVKYKDKYPGLKDE
                     SLYELNTKDKDTIDDLNVIFGKAILIVSGLEGDSKEVKAMKAQLMSKLPPQATQSGDV
                     DIFKLLSAMPKEQLDTLTKEMSKGFESMPESMITQSSVSYVRSEYEKIGIDTEKTQNN
                     YILFTGAKMLGIAMISMVATITVGFLAARVAASVGRNLRSGVFRKVMSFSNTEMNEFS
                     TASLITRSTNDIQQIQMLMVMLLRIVFYAPIMAIGGVIKVLNTNTSMAWIIAVAVVAI
                     LSLIVVLFSVVMPKFKLVQKLVDKLNLVSREIITGIPVIRAFSTEKHEEERFDKANKN
                     LTKTNLFVNRVMTCMMPAMMLIMNLITVLIVWRGAYSVDSGAMQVGDMMAFIQYTMQI
                     IMSFLMISMVSIMLPRASVSATRIDEVLVSDISIKDPEKSEAQEFKEDKKGLVEFKNV
                     SFMYPDAEEPILTNISFTAKPGETTAFIGSTGSGKSTLINLIPRFFDVTEGEILLGGV
                     NIKNVSQHDLREKIGYVPQKGVLFSGTIESNLKYGRKDATDEEMRTAAEIAQATEFID
                     SKPEAFKTEISQGGTNVSGGQKQRLSIARAIAKNPEVYIFDDSFSALDLKTDAALRKA
                     LKSKTAESTVLIVAQRISTILNAEQIIVLNEGEIVGIGTHKELLKNCEVYEQIALSQL
                     SKEELANE"
     gene            complement(66064..66525)
                     /locus_tag="ACGI5H_000715"
     CDS             complement(66064..66525)
                     /locus_tag="ACGI5H_000715"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family winged helix-turn-helix
                     transcriptional regulator"
                     /protein_id="HFG9696444.1"
                     /translation="MNSNSEEKLNDVFLQLMRIYFIRTHFYFDKLGLYHGQPQILFSL
                     KMKDGQSQKELADKRKVKASTTTVMIKRMEKAGLVERKQDEKDQRVSRIFLTDKGLEI
                     CNKVEEFNKELEREFFLGFSEEEKIVLRRLLMQVRDNLKAGCHKHEDEKYF"
     gene            complement(66830..67396)
                     /locus_tag="ACGI5H_000716"
     CDS             complement(66830..67396)
                     /locus_tag="ACGI5H_000716"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423380.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-class carbonic anhydrase"
                     /protein_id="HFG9696445.1"
                     /translation="MRKLEEILEYNKSFVENKEYEQYVTSKHPNKKIVVLSCMDTRLT
                     ELLPKAMNLKNGDVKLIKNAGATIMHPFGSIMRSVLVAIYEFDVDEVMVVGHHGCGMC
                     NVDTDKLLGKILDRGISNDVILTLRSAGIDTKQWLHGFDSAEESVKDSIDLIKGHPLI
                     PDGIIVHGLIISPETGKLDVVVNGYEDK"
BASE COUNT        22659 a        11243 c         7474 g        26238 t
ORIGIN      
        1 ttttctttag ttaattttta ttataattta tataaattgt ataaaaattt tcttcagtta
       61 cttgttgtta aattaaattt ttacaagcta accctaccag aaaagagtta tctaatctgt
      121 aaggaaatag tttaatatag cacattatac ttgtgtaatt aataactttt cttttgtaga
      181 aacttttctt tacaaagaaa agttttttga ttttggattt gtttaagaca tattttctga
      241 gttaggagga tatttatgaa aaaggttgca gttataagtg ctattttgga agaaccaaaa
      301 gaatgtcaat ttaaattcaa tgaggttgta tcaggtttta aaggtattat taaaggaaga
      361 atgggcattc cttgcgaaga agaaggtgtc tcaatcgtat gtatagcagt tgttggcgaa
      421 atggacacta ttaatagttt gactggtaaa ttgggcaaca tacctcatgt atctgtaaaa
      481 actagtatat caaaaaaaga agtttaaggt ggtgagtaca aatgagtcta aattctactc
      541 cacaatcggt aagagtacat ataggtctct ttggtaaaag aaatgcaggt aaatctagca
      601 taataaatgc tataacaaat caaagtgctg caatagtctc agatattgct ggaactacta
      661 cagacccagt atttagacca atggaaatcc ttcctatagg accttgtgtt cttatagata
      721 ctgctggtct tgatgatgtt ggtgaacttg gtgaacttag aataggtaaa tcactagatg
      781 ttttagaaaa gacagatata gctttactag tagtggattg ccaaattggt atatcacaag
      841 aagatttgtc actaattgaa aaatttaatg ataagaatat ccctcatatt ctaattctta
      901 acaaaattga tactattaag aatcaatcag aaattttaaa cttaactaaa aataaagtta
      961 aatgtccagt tgtttctgtc tcatcaacag ataaaattgg aattgaaaat ttaaaaaatg
     1021 aaataataaa agttttgcct aaggatagca ctgagttcaa attggtatca gatttaattg
     1081 aaccaaatga tttagttgtt ttagttgttc caatagataa agcagctcca aaaggtagac
     1141 ttatacttcc tcaacagcaa gttataagag atattttgga taatggtgca atttctatag
     1201 ttacaaaaga agatagttta aaagaaactc tatctaattt aggcaaaaaa ccaaaacttg
     1261 ttattactga ctctcaagta tttccacaag tagataaaga tacacaaaaa gatattcctc
     1321 ttacatcttt ttctatattg tttgctagac aaaagggaga ccttaaagaa ttgattaatg
     1381 gagcttatgc tttagaaaat ttaaaagatg gtgataaaat cttgatggcc gaaggatgta
     1441 cccatcatag acaaactgat gatattggaa cagtaaaaat tcctaatatg attagaaaga
     1501 aaactggcaa aaacattact tttgaattta gttctggagt atccttcact gaagatataa
     1561 ataaatatgc ccttgtagtt cactgtggag cttgtatgat gaatagagct ggaatgttat
     1621 ctagaataga aaaggcaaaa tctttcaatg tacctattgt aaactatggt gtcttaatag
     1681 catatgtaaa aggtattttg gaaagatcac ttgaactttt caattattaa aaatttaact
     1741 atacttaata attacatatt tgaatatgac taaaaataag attaaatact ttatagataa
     1801 actttacagc attaattcat taagttttga tgaactacta tatttaatag aaaatatcga
     1861 caatgaggaa tataacttcg aacaaaattt aagaaactat ctttataaac aagctagcga
     1921 catgagaaat aaacattatg gaaatagagt ctacttgaga ggacttatag agcttacaaa
     1981 ctattgtaaa aataattgct actattgtgg aatacaatct tctaataaaa atatcataag
     2041 atacaggctt tcacttgatg aaatacttga atgttgtgat ataggttata aaataggata
     2101 cagaacattc gttttgcaag gtggtgaaga tgcatatttt actgatgata aaatatgtga
     2161 aattgtttca agtataaaaa ataaatatga ggattgtgcc ataactctat cactaggaga
     2221 aaagagttat gattcgtata aaaaatactt tttatgtggt gcagatagat atcttttaag
     2281 acatgaaact gctacagaca gtcattataa aaaattacat ccgccaaaca ttgagcttag
     2341 aactagaaaa gaatgcctaa aaaaccttaa agaaattggt tatcaggtag gtgctggatt
     2401 tatggttgaa tcaccatttc agaacaacga agaccttgtt cgtgatttat tatacctaaa
     2461 agagttaaat cctcatatgg ttggaatagg accttttatt ccacaccatg atacaatttt
     2521 taaggattat aaacatggag atttagagaa gacattactt atgctttcaa ttacaagact
     2581 tctacttcca aaagttttat tacccgctac aacagccttg gcatctataa accctagtgg
     2641 tagaaatgca ggtcttttag ctggttgcaa tgtaattatg ccaaaccttt ctcctcaaga
     2701 atttagaaaa caatattctc tttacgataa caaagccttt actggtcaag aagcttgtga
     2761 atatcaccaa agtttagaag aaaacatcaa gtcattagga cttgaagttg actattctcg
     2821 cggtgataat attgaatgga ggcgtttgta aatgttcata aaccatgaac ttattaattc
     2881 tttattagaa gatgcaaaaa attcaacttc tgatgatatt gaaaaggtac ttgataaggc
     2941 tgatagaagg gaaaaactta gttataaaga tatagctaca cttcttgaag tagaagataa
     3001 aaaacaacta gatagattat ttagtatagc tgggcaaata aaaaatgaaa tatatggtaa
     3061 tagagtggtt ttatttgccc ctctttatgt atcaaactac tgtgtaaatg aatgtgttta
     3121 ttgcggtttt agtaaatgca acaaatttaa aagaaaaaaa cttaccatgg aagagataaa
     3181 ggaagaggtt aaaatattag aaaaaatggg tcataaaaga cttgctctag aagctggtga
     3241 agaccctaaa aattgtgata taaattacat cttagattgc ttagatgcaa tttattcaac
     3301 atataatgaa aacggaaata taagaagggt aaacgttaac atagcagcta caagtgtaga
     3361 tgagtataaa ttactaaaag aaaaaggaat aggaacttat atattattcc aagaaactta
     3421 tcacaaacca acatttataa aaatgcatgg tcaatctata aaaaatgact attattacca
     3481 tttaacagct tttgatagag ctatggaagc tggtgttgat gatgttggtg caggagtttt
     3541 atttggttta tctgacccta aatttgaagt tctaggactt atgatgcaca acgaacactt
     3601 agaggaaaaa tttggtgtag gtttccatac tatatctttc cctagattga aaaaagctga
     3661 aggtatgagc ttagaagatt ttcctcactt agtttctgac gatatgttca aaaaaatagt
     3721 agctataact agattggctg ttccttttac tggaatcata atgtccacta gagaaactgc
     3781 tgaaatgaga aatgagttac taaaatatgg tgtatcacaa attagtgcag gttctctaac
     3841 aggtgttgga ggatataaag catatgaaga tggtgacaat acagaacaat ttgaagttgg
     3901 agaccataga agccctgttg aggtgcttaa agaactgatt actgatggat atatacctag
     3961 ttattgtaca gcttgttatc gtaaaggtag aactggcgat agattcatga gcttagctaa
     4021 aagtcgacaa atccataatg tatgtacacc aaatgctctt actacattaa atgaattttt
     4081 aatcgattat ggagatgaag aacttaaaat tatgggtaaa aaacttatcg cagaagaaat
     4141 aggtaagata gaaagagaag atataagaaa catagtatct aacaatatga ctgccttaga
     4201 gcgtggagaa agagatttat acctataaaa ttttattact tatatattat ttattgtata
     4261 ttccataggt tagtagtaat attatctaaa gggaaagttt aagggaggga gattaacatt
     4321 gaaagataac aacaatacca ataaaactat tcaatttgga gaaaaaaagg ctagcctgga
     4381 aaacaatatt caaaaaaata aaaatatcaa acttgataat acacacaaag tcattcctta
     4441 ccctaaaaat agaaaaaagg atgataaaaa gaaaggtaac aagaaaaaga atacaaatac
     4501 atctaaagta aataaaaata attatggcca ttcttttttc aataacaaat acaaatataa
     4561 aagaaaacca tatgttattg ctttatacac agtaattctt attcttttag ctatcttaat
     4621 tataactaaa ttaacagata gtacgaataa aggtaattat tctcgtaata ctgtctctga
     4681 tactcacaaa aacgacatcc gaaatatagt ctttaatgaa tcaaacaatt ttcttatttg
     4741 tgggtaactt aaaagagtta tctcatttca gaaataattt tctaaaattg agataactcc
     4801 tattttcatt taatatttat tttaccaacc ttgagttact tcatatactt catcaccaat
     4861 tctaccattt aaataatcat ctattgcaga atctatgatg ttcattgctt tatctacttg
     4921 ctccttagtt attactagag gtggttgcac tcttaaagta gattgtccta agaatatcat
     4981 tattaatcca gtttgtatac atctataaca tatcttagct gtagcatctg gatgtttttc
     5041 attagaacct tttcctttaa ctatatcaac tcctatagat aatcctatgc ctcttatttc
     5101 tccaattata tcgtattttt cttttagttt ttcaaatcct gctttaatat aatctcccat
     5161 ttctatactc ttttgaagta agttttcttt ttcaattatc tctatagatt ttaaagcagc
     5221 cacacatact gttgtgtttc cagctaaagt aaataaatgt gctggtgcat caagactttg
     5281 cattatttct gttcttccaa caactgctcc tagaggtaat ccacctccaa cagattttcc
     5341 aagaactata aggtctgctt caacaccaaa attttctata ccaaaccact tacctgttct
     5401 tcccatacct tgttgtattt catcacttac aagtaatatt ccattttctt tacatatttt
     5461 acttaaacct tgtacccact ctactggagg cactattatt cctgcatctc ctgcaattgg
     5521 ctctataaat attgcagcta cctcttctgc tggtagatag tgtgcaaaag catattctat
     5581 ctcatctaaa cattctttag ctgttctatt tttatcagga taatggaagt gataaacttc
     5641 tggtaacaat ggacccattt ttcttctcat atttgtactt aaagcagata tagatatagc
     5701 tccataagta cttccatgat aagattcaca catagatatt atctttgttc ttccagtata
     5761 tcctcttgct aattttatag cagcatctat acaagcagaa ccagttgcac tgtatagtac
     5821 ttttttatca ttatctccag gggctatttc cacaagcttc tcagctaatt ttacaggagg
     5881 atcactatgg aaatatgcaa gtgtatattg tgttatatca tccatttgtt ctttaactgc
     5941 ttgtgagatt tccttattac catgacctac atttgcagag cctgcacttg ctaaaaaatc
     6001 tacatattca ttaccttcat aatcatatag cattgcacca tcacctgatt taaatgctac
     6061 tggataataa ggtatctttt gagttttagc aacatatttt ttttcttctg tacttatcat
     6121 ttgactagtt atctcgctca ttggcaaatc atcccctctt taaataaatt tatgttttaa
     6181 aattattgcg atttataaag atattctcat ataaaattct ttatatactt aatgttagta
     6241 tttttgacac aaattgtcaa tatatgtttt tataattttc aaaatatttg ttattcagaa
     6301 acaatatatt ttatttttat caaataaaca ttatttttca aaaaataaag gactctattc
     6361 tatttttata gagtcctctg aaaatcatct tataaatacc attattctat tcgtcttcat
     6421 taaattgtat aattaccttt tctcattaat aattttttta aaatgttcta gttgctcttg
     6481 ttgtttttta tgttttatat gtggaaaagc ttttataact cttttttgta aaataatatt
     6541 agactctata cggtccaact tactatttat tttgtttatt ttttctctaa cttctaattc
     6601 gtcgttattt attgttttaa ataaagcttg tatttctcct ctatcaaatt tatccaattt
     6661 cacatttata tcattaaggt ctgtaattat atcgtctagt aagtttaact ttatatctaa
     6721 ttttttaagt gttataatag taacaatcaa atcaagtata gtccaaagtg ttgtaattat
     6781 agccattgaa attaatattc tatatggaat tatacttaca aaatatttta taaatggatg
     6841 tataaatctt attattaaaa cagacattac accaaagtat attgcatttt ttaaacatac
     6901 tctacccttt atattgaatt ttctgtcaga ataatcccac catttagcat gaaataaggt
     6961 ttctaaaata aatcctgtaa aatattctag tatcgtagtt aaaatcattc ctaatagaaa
     7021 tactattact acattattaa atcttcccaa tagtgatatc acaattaccg ctccaaaacc
     7081 ataaacagga catattggac catttaaaaa acctctgttg attattcttt tgcttgctat
     7141 agaacatcct atactttcta ctgtccatcc taaaaatgaa tatataaaaa agtacaagat
     7201 atattttatt atctccataa tttatctcta ctccttcact aatgttctta ttttatgcac
     7261 aacgtaaaaa taattataga aatagttttt tcgtttttta tatttgttat tcttttattc
     7321 ttgtttaata ttttattcat acaatccaat taataattta ctagccataa taccatgttt
     7381 atcctttggc tgattttctt tatcaatcca aacattaata gtatcatatc tccttaataa
     7441 atctaaattc ttcacatcaa attcctcata tttaactata tccatttttg attctttggt
     7501 aattatataa gatactaatt ttgtattttc atttaaataa attcttatat ttccatcaga
     7561 atcaattaaa ttctctggtc tctttacttt gttattagaa cctgctttaa tagttattat
     7621 tcctttttta aagctctcaa atgtcccaac tatatctact gtatctttat ttatatcttt
     7681 aattatttcc ctattttctt caattaatat ttttgatatt tttctatcag gtctaaattt
     7741 aaaagttagt aagttatgat aatttttaga aataactcct aatcctataa ctcctaaaac
     7801 taaactagta cctattatag ccttaaatct gttaatatca ttgggaaata atttattcat
     7861 gtttatgtaa atattaattc caattatgcc acctaatgaa tttaaaataa catcatctat
     7921 atcactactt ccaagagcaa aaatatattg tgttaattca aatgctaggc taacaagtat
     7981 aattactata attatagttt ttttatttag atttttacat actataggta aaaaaattcc
     8041 cataggaata aatataccta tattttctat aatatttaca gtagctttca taaagtcaag
     8101 attactatct actataaatt gatatattgt ataaaatgga attaaattta cattcctaaa
     8161 cgttcccttg aaaatagcgt aaattggtac atctctaaat aaaattattc ttataatcat
     8221 taaaatatat accaaaaata ttatgtatat aattgacagt aacaattttt ctgacttttt
     8281 actttctatc actgataagt ctcctttcgc tattaatatt ttaagtatat caataaatat
     8341 ttaagacgat tttaaaattt ccttaaaatt tccttaattt tcaaacaaaa aatcaaaaaa
     8401 gcctacactt aaatgtgtag actttaataa atttttatac aaatacattt tattgaataa
     8461 cgaacaatct taatgtagaa aaaactataa ctacagttaa aagaagtcta gcatataaaa
     8521 aatttttttc tttcaacata actcctgcaa ctccaaatat aaaaaataga gaagcaataa
     8581 attttccaat aagattatta ttaggataat aactaaaaag cataaaacaa agtacaaatg
     8641 taagtactcc tattgcatta aacacaattt tattagatgc tatttttcct ttattgaaaa
     8701 agaaacagaa tattgacact aaatctaaaa ataaaaatac ataaaacatt ccttttaaaa
     8761 cgcccatttt tataccccct aaaaattcta attataatat ccagtttatt tcatataatc
     8821 gtcaatataa tcaatacttt ataacatcag tataacagta ttacaaattt atattacgaa
     8881 tgtactactt cgtattcata catattataa tcacactcat acatatttaa agactcatat
     8941 gttgcttttg catttatgtt ttctttttct acatataatc tcattccaac tatattttca
     9001 tctttatcac atatattttt tatataatta aataaataat taaagatacc ttttcttcta
     9061 tattccttat ctacatatac actctgaatc caaaggaaat ttccatttct ccaatcactc
     9121 cactcatatg tatacataat ctgtgcaaca actttatcaa atactgtata tacatgatat
     9181 tttccttttc tctcatctaa taacaatgct tttacacctt tagttaaaac atccatatca
     9241 agttcttttc cttcagtttc tttagccaaa ttataattaa attttgctat tgtatccaaa
     9301 tcatccatac gtgcttctct tatctctatt agttcttcat tttcatataa ctctatgtag
     9361 tccttttgtt gctccatact tattcctcca tatctatttt atctactaag gttttttata
     9421 taatatattt atagagtttt ttctatcttc ataaatgcat aatcaagtgt agcctctaaa
     9481 tttccattat tcttacctcc tccttgagct aatactttac ttccaccacc cttgccatct
     9541 ataagattta ttgcatcctt taataaaact cccatattaa tatcttttaa atttttagaa
     9601 catgcaaaaa ctaaatttat tttatcatta aatttaacag ctaataatgc aatactattt
     9661 tcatattctg caattttatt tgctatctta tttacatatt tcaaatcttc atcatcataa
     9721 atttttttaa tgaccgaaat attgccaacc ttatttgctt tttcaatcat ttctttgacc
     9781 tgatatgtag atactacttc ttcaagcctt ctttttttaa ttaaagcctc ttccacttta
     9841 ctatttagat ttacaatacc atttatagca tcttcctcac tacagcttaa atatctacat
     9901 attttagtca aatatatatc cctcttcaat acttcatcca ctgccctttt acctgctaga
     9961 aactctattc ttgtacttga cttatgtttt tcccatttct ttatttttat cattctcaat
    10021 tcaccagttg attttggatg cactccacaa catgcattcg tatctaaatc acctattttt
    10081 attactctta tctcttcatc agtatttggc aaatcacgtc ttaaccaaat cttttttagt
    10141 tcttttttcg ttggaagtaa tgtctctact tgtatatttt gacgaataat ttcattggca
    10201 aacaactcta tctctctaat tttatcctct tctaaattac cttctatatc tactgtacta
    10261 tactcatttc ccaaatgaaa acctgtcgta tttgcattaa aagttttaaa aaaacatcca
    10321 gacaatacat gttgtccaaa atgttgatgc attccatctt ctcttctatc ccaatcaata
    10381 ctacacttta ccttatgtat ctttataggt tttttatcta atacatggta tatttttttt
    10441 ccatcttcat acacatttat tacatcatca ttctctattt ttcccaggtc tccaaactga
    10501 cctcctccac caggaaaaaa agctgtctta tctaataaaa catgatactt attttctact
    10561 tcttttattt caattatttc tgctgtaaaa tctcttatat actgatttgt ataatataat
    10621 ttttccatta taattctatc tccattttct taattctaga ttactttact ttttagatac
    10681 aaatttcaaa ctaagcttaa tttaattgta ttaaaataga actcatccta ttatttacta
    10741 acatcttcta ctatatttta acatatagat attaatgtta acaaatttat aattgtatat
    10801 tatttcaata ttttataaca tgtatgttta cttattttct tatataataa aatgtatatt
    10861 aaaacatgtt aaattgcaaa ataagcttca atctctttta ctaatttcat ccattattaa
    10921 tgattttgaa atatacatta cttctataat attcttaaaa cgtgtatgat gagatgtctc
    10981 ctcagaaaat ttcttctgtc cttttccaca attaataata cttgaagata ctactctcag
    11041 tgcttccacc aattcttctt ttgtatgata attcataaca catttactcc tttatttttt
    11101 aatttagaga aacagtatat ctcaatttaa tatcattata aactgacatc attattattt
    11161 atacacatct tttagcactt aaatattcta actatcagtg acattacata ttttaataat
    11221 tattaatata catataatac tttaatattc actaatagag agtatattaa cattgctttt
    11281 ttaaaaattt tagtataaaa tcatattaaa taaattttct gaaataatag aatattaaaa
    11341 tatccaaaaa cagcttttaa taacatctat aattttcaat gtatcgttat tttaggggga
    11401 gtgatttaaa atggcaataa agccaagaaa aatatctatt gtaggttcag ggcatgttgg
    11461 ttctcattgt ggatttagtt taataactca aggagtttgt gatgaactct ttatgattga
    11521 tatagatgaa tctaaatcaa aagctcaagc tttagattta gctgatgcag tttcatatct
    11581 gccacataaa gtacatatag aaaaaggaac tttttctgac tgtaaagatt ctgacatagt
    11641 agtgataagt gttgcagact cttcagaagg gcctttacgt agacaaaaca caactagatt
    11701 agatttacta agaccaacta ttggaatgat aaaatctata gtaaaaccca tagttgattc
    11761 tggctttgat ggtatatttg tagtcatatc taatcctgtt gatgtagtta caaattatat
    11821 ttgggaaaaa tctggctttc ctaaaaacaa agtcattgga actggaacag ctttagattc
    11881 aacaagactt agaaggattt tatctgaaga aactggaatc gctcaacaat caattcaagc
    11941 ttattctatg ggtgaacatg gagattctca aatggttcct tggtctcatg tttcaattgg
    12001 tggtaaacca atcttagaca tgataaaaga caacccaagt acttatagca atttagactt
    12061 accatcaata gttgaaaaaa ataaaaaaac agggataagt ataataaatg gtaaagattg
    12121 tacagaattt ggtataggta ctgctttagt agaaattgta aaagctatac tacacaatga
    12181 gaaaaaagtt cttccagttt ctacattact agaaggtcaa tataacgaaa gaaatgtatt
    12241 tgcaggtgtt ccatgtgtta taggaaaaga tggtattgaa gaaattattg aaatcaatat
    12301 gactgaatat gagcaaaatg aatttaataa atcttgttct gttttaaggg aatatattgc
    12361 actttcaaaa acactttaga ttcaatattc tttcttacac taaaagcagg taaatgactt
    12421 attgaaaaga cctttaacta agttaatgtt taaatcattt gtacctgctt ttaattttaa
    12481 tactaaaata taaacctatt ttttaccatc aaattttata actttacttt ttttatttac
    12541 ctcttgagat aacaatcctt ttttcaatcc catcaataat tctaagtctt ctggataaag
    12601 atttattcca aattcctcta aacttgatac tatactattt acactcatta ttttattttc
    12661 tatcaataat tcaactgctc tttttaaata cgttgggctt gaacctttca ttttgtctag
    12721 tggttcttct atcaaccagc cttttttatc catttcattc ataagataat tgtatttttt
    12781 gtaatttatc ttttctagat tatatgctct aaaaatcata gcagatatag gtacaatcca
    12841 ttttttcttt agttctacat aataatctaa atcttctgga tgagtcaaat cttttaaaaa
    12901 actctctttt ggcaataaaa atgcacaggc atactcatct tctgaaaatt gcttacttgg
    12961 tattcttaat tcacttgata ttatatatcc aagctcacat gccaaagtat aatttctaat
    13021 tgatgctgac tttttgtcat tacccagaga tattagatat ttagattctt tactaattct
    13081 ctgtttttga gtaaagatag ttgccccttt tctatctaca ttcatacctg atattataat
    13141 ccctttagac tctaacaaac ttaccatatt tactattgga gtactattta aatcccaaaa
    13201 ctctctagtc ttatatgcaa gagattctat atcatttata ttaatatctg acattacttt
    13261 tctatttggc aagttttctt ttggaaactt aatataattc tccataaatg aatatatttt
    13321 atgtattata attatttttt ctctataaga aatctcttct actctaggta gtttagattg
    13381 agggttaaag tggctatcct ctacaacgat atttatattt tcatttttat aaaaatactc
    13441 ttttggaaaa tttaatatat tagataattt taatgtattt tctatatttg gtacatactt
    13501 attttcctca aaagctttta aatctttttt atttatttta gtttctttag acaactgttc
    13561 tatcgtcttt gctctaaaaa ttctagctga ttttaatctc tttccattaa agtcttttaa
    13621 attcatttgt tttctctctt tcaaaattaa attcttaatc tattggtata aataagatta
    13681 caattaataa tttatcatat tattgacaaa aaaacaaaag gtgaaaatat ttttttatat
    13741 tttcaccttt tagataagtt tataataaat attcctaatt actcaaaaag ttttaaatat
    13801 tctccatatc ctaaagcttc catattttct cttggtataa atttaagaga agcagaattt
    13861 atacaatatc ttaaacctcc aagttctttt ggaccatcat caaatacatg acctaaatga
    13921 gaatttcctt tagcacttct tacttcaact ctgtacatac cttgtgagaa atcacttctc
    13981 tcaatgatag atttatctat aactggcttt gaaaaacttg gccacccaca tccagaatca
    14041 aatttatctt ttgaagaaaa taacacttct ccacttacaa tatcaacata aattccctct
    14101 ttgttattgt cataatattc attttcaaaa ggtacttctg tcatatcatt ttgagtgact
    14161 tcaaattgta taggagttag agtctttttt aactcttccc tatttatatt gtttccatcc
    14221 caatggcttt ttacaaaatt atatcttcca gaccctttat aatacatatt gtagtttaat
    14281 ggtcttttct tataataatc ctgatgattt tcttctgctt cgtagaattt agttgctgga
    14341 attatatcag tcactatttt actatcaaat attttactat tttccagatg ttctcttgac
    14401 tctaaagcta tatttttttg ttcttcatca tgataaaata tagcagtctt atattgagtt
    14461 cccctatcac caaattgtcc accatcatct gtaggattaa tctgtttcca gaagatattt
    14521 agaagttcat cataacttat tatatcatca tcatatgtta tttgaattgc ttctaaatga
    14581 ccagtagttc ctgagcatac ctcttgatat gtagggtttt caacatgacc acctgtatat
    14641 ccagaaacta ctttaataac tccatcatac ttatcaaaag gttttaccat acaccaaaaa
    14701 catccacctg aaaaagtagc aagttttatc attttcatca ctccttaaat aaattatact
    14761 ttatttattc cctaagaagt aacttaataa tctgcatttt attattttta cctactcaat
    14821 gaaatcatgt gtaaaaatac aattgcaaat tgaatctaat ttctataaaa gctctttttc
    14881 tttatccatc caaaagcatc ttttatatca caattttctc ctaaagacat tagatattct
    14941 aatgcatcac aatcatccat agctacatct ttttccatct taggatttaa tctatagtaa
    15001 ttatctccaa gaagtttttg agaaaataac tgactcattt gagaatttcc ttctaaggta
    15061 atagatataa ttggtaaatc gggttcttta ttaattatcc agtcaatagc tccccattcg
    15121 gtagtatctg cctttatact gttatataca tatccagtcc ctattgaaaa aagtcttgta
    15181 ttcttaagtt taaatccact gtcaatggca tgaattatac acgctaaact cgggtcagtt
    15241 gctattattc ctccatcaac atgacgatta tatgttggaa aaaataccgg agcagcacta
    15301 cttgccattg ctacatctac aactttgcta gtctttgtaa aagaatttgg catattgtta
    15361 taaaacactg gtttccatgc attttcctca tttcctatat aaaaacttgg tatcattact
    15421 aatttattta aatcttttaa ttctagttcc tctggaaata tacttaataa aacttctttt
    15481 aagtttttgt tttcatactt tggtctgagt atttctgcat aacttttatt aaaaatatac
    15541 tttgaatttt caattgagta aagttctttt atctctttag ggcttacacc atacgcaagc
    15601 cctagtgcaa ttagactccc tgtagatgta cctccaaaca tatttatatt gtttaataga
    15661 tttggatact cttttactat cctctcaagt atggatatac tcaatgcccc ttttaatcca
    15721 ccaccatcaa atgccaatat attaaaatta gaatttttca tatacatata cccccacata
    15781 aaacacctta tattttaaat tttaatcaaa ataatttcac tatagtatat atattttatg
    15841 caagttacat attacaatgt tcctctttta atatttaagt tacattcaaa cctttaatac
    15901 ttaaaataaa atatataaga tattatatat ctaagtatta taaatttaat acaaagattc
    15961 ttaaaaagaa tatactgaaa gcaggtttat ttttcaatta ttacaaaaaa taaataaagg
    16021 gtcatctcaa aattgatttt ttaatcaaat tttaagttta accccttatc ttaattgtgg
    16081 catacttaaa aatattttaa ctataaatat ctttaagtat agatatgttt atttatccta
    16141 aaatcttctt catatcttct tcaggagtag atataggtgt caatgcaaat ttatcaacca
    16201 atatatctaa tacattctta gataagaatg ctggcaaaga aggccctata tagatatttt
    16261 tgatacctaa atgaagtagt gtaagaagta tacaaacagc tttctgctca taccatgaca
    16321 gtaccatgct aagaggcaaa tcatttactc cacattcaaa agcatttgcc aatgaaactg
    16381 ccactttaat tgcactataa gcatcattac attgtcccat atccattaaa cgaggtaagc
    16441 cacctatatc cccaaggtct aaatcattaa atctatattt tccacatgca agtgtcaata
    16501 taacagtgtc tttaggagct tgttttacaa attcagtgta ataatttctt ccaggttttg
    16561 caccatcaca acctccaacc aataaaaagt gtcttatagc tccactcttt acagcatcta
    16621 ctactttatc ttgtacagat gaaactgtac ctcttgcaaa accagtagtt aatgtatctc
    16681 ctccattaat accagtcata tgaacatctt ctctatatcc tccaagttca agagcttttt
    16741 ctattacact agaaaaatct ttatcttcat caatatgaac catacctgga taagcaacta
    16801 cttctgtagt aaatactcta tctctataac tatctttaac aggcattaaa cagtttgttg
    16861 taaataatat tggagcagga atattatcaa attctttttg ctggttttgc catgctgtac
    16921 caaaattacc ttttagatgt ttatattctt ttagttttgg atatgcatgt gctggtaata
    16981 actcaccatg agtatatata tttataccct tatctttcgt ttgttctaat aatttgtgta
    17041 aatcataaag gtcatgtcct gtaactacaa taaatggccc tttctcgatt ttcatagata
    17101 cctgagtcgg ttctggtgtt ccataagttt cagtatttgc tctatcaagc aattccatac
    17161 attttaagtt tatttctcca gttttcataa ctagacctaa aagttcgtca atagacaagt
    17221 ctcctccaac tgctattaat ccttcataga aaaattcatt tacgtctttg tctgtataac
    17281 caagtaccat tgcatgatat gcataggcag ccatacctct taatccaaat aagattaatg
    17341 attttaatga acgtatgtcc tcattatcat tccataaatc cttcatatca tagttatcat
    17401 ttctattaca agttgttgaa caatctgaac atctaggtac aagtttactt ttttctacct
    17461 cagttttttc aatttgtctt tttatagctt catcatcaaa acttacattc gttatagtag
    17521 tgaatagccc ctctatcata attttatctg tttcacttgt tggtctattc ttatttccaa
    17581 tagttgctct tgaaagacca atcaacactc ctgtaagttc gtcttgtaag ttagctgtac
    17641 cccccttttt accacagaca ccatttatag tacaaccttt acctcctgct gtttgttcac
    17701 attgaaaaca aaacattttt tccatttttt attcctccct ttttatttat taaaatttat
    17761 tatatttttc tataattcac ttaattaaat ttctccatct acaatttttc catctacaga
    17821 tatagtaact atttgccatg gtatcatttt tccactattt tgtagagctg tcttaacagc
    17881 atttactata ccaccacagc aaggaacttc catacgtgtt actactatat ttttaatatc
    17941 attttctttt aaaatctctg taagtttttc agcatagtca acttcatcaa gtttagggca
    18001 tccgattaat gtaaccttat ttttcataaa tttattatga aaatttccat atgcatacgc
    18061 tgtacagtct gctgctatta aaaaacttgc attctttaaa tatgatgcat tagttggtac
    18121 taattttatt tgtactggcc attgattaag ttgagaacct tttatctcta ctatatcatt
    18181 gcttatagac gtactatttg aaacctctct atttattgac ttagactgag aacctggaca
    18241 tccacatgct aaagttttct tttgtgcttt ctttgcttcc atatttgctt ttactgcagc
    18301 ttcatcatat tctgctgctt ctctatactc aaatgaaatc gcatttgttg gacaagttgg
    18361 cagacaatct cccagcccat cacaatagtc atctcttaaa agttttgctt ttccatttac
    18421 cattcctata gcttcttcat gacaagcttc aacacatagt ccacaaccat tacacttttc
    18481 ctcatcaatt ttaattattt ttctcatcat ttatatcacc tcataaaatt tttttaattt
    18541 aaagtattga tttcttatat atttattttt aatacctata tttctttatt tcaaatttct
    18601 tgtagtagga tttttatatc cccttgcttt tataaactta gtatagtaca atgaaaacaa
    18661 attatcggtt gcatatgcaa caaggaagtg attatttgaa aaaattttta gaaaagcata
    18721 tagacttact taaaaaaatt cctctatttg aaggaattaa aagtgatgaa cttgaagaaa
    18781 tgttggaatg tttaggtgtt gtagataaga cttacccaaa agatagtata atattctctg
    18841 ttggaagtga agttacttct attggaatta tgcttaaagg aagtgctcat ataataaagg
    18901 aagatatcga agggaatagg aatattgtag ctgaactctt gcctggagat ttatttggag
    18961 aggtattcgc atgtactaga ctacataaaa gtaatgttac agtaaccaca acatcttctt
    19021 gcgaagtttt atttataaag tttaaaagtg taactggtat ttgttcatct gcatgtgtat
    19081 ttcataatag gcttgttgaa aatatgctac aattaatagc tgaaaaaaac attttacttc
    19141 acaataaaat agaattactt tctcgtaaaa caactcgcga gaaattgctt atgtattttt
    19201 caaaacagat agaacaaaca ggtagccacc agtttacaat tcccttttca agaaatgaaa
    19261 tggctgattt tttatgtgtt gacagaagtt ctatgtcaag agagcttggc aagatgcgag
    19321 atgaaggctt gttatctttt aacaaaaata aatttgaaat cttttatttt caaaacaagt
    19381 tagatatcta ggcttgtata atatctgtat tcaaataata ttgtttttta ttagttattt
    19441 tctagaaacc tttatacaaa aaaggagtat taataattaa tgctccttta gctatactat
    19501 aaattaaact tttatctatc cattgatatc aatggctatt ttcattccaa gtttataggc
    19561 ttttttcaat accttaaaat tttttttagt ggaatttctt tcaaatgctt tggttacaac
    19621 tatagttttg tagtgattta atcccatgcc ctttaaatgt tttgcagtat acttaaaata
    19681 ttttttaaat aaaaacgaaa taggagctgc ttgagtatag accatgatta actttttttg
    19741 accaaaccta ggtatatgtt tagacttatt tatctctgtt aaaggataca atctatctaa
    19801 aagtagcttt gtttgagctg atacctgaca tatatatact ggcgaaccaa ttattatata
    19861 ttcagcactt tttatatctt catatatgtc aatcatatcg tctttaaatg cacaagtagg
    19921 aacttttcta cagtatagac agccttgaca tcctttaata ttcatatcat ttagataata
    19981 ttttttaact tcaacattat tatcatttac accttttatt atctcatcaa gtattgtgtc
    20041 tacattccct ttttttcttg gactgcccat aaaggctaat acttttacca tattaagttc
    20101 tcctgtctaa tttatttttc taaatttaat ctaaagcaca ctttattcta aaaatatatt
    20161 ttatatactt tgtatttgtt ttatttacat tttatattac aaaagtatat caaaaaataa
    20221 ttcttaacac aattatttaa aagtagtata gcaatttaat acaattattt attaaatttt
    20281 aatgctcctg tagggcatac cattacacaa ggtgaatcca taccacactt atatctctca
    20341 atacaaccat tacacttatt tgccttacca tcatttccat aaattaaggc tccatattca
    20401 caagcttttt cacaaagttt acaccctata cagttttgat tgtctaatac aatgaatcct
    20461 tcttcttttt taaaacaatt tttaggacat acacctaaac attttggctc attacaatgt
    20521 atacatgcta atgaaaaata ttctatattt tcaccttcct ctattgtaaa tacatgtcta
    20581 aaaagttcac cattgtctat attattatca ttttggtcta tacatgcaag caaacatgct
    20641 ccacatgctg tacataattc tttattaaat ttaaataaac ttttcattat atctctccat
    20701 ttatctattc attttttcaa tcttacactt acaacttcta tacgcaggga atccactata
    20761 agggtcaaaa ttatcacaaa taatactatt tatatcagct tctctatatc catgatacat
    20821 atgtatattc ttatataaga ctctatcagt aacattgact tttacatcca aacttcctat
    20881 cttagtagtt atttttatat aatctccact gataacaccc aattcttttg catctaagct
    20941 agaaatatca caattagctt cattttttaa tattcttgaa agtttgatgt catgaagtct
    21001 tgaatgtagt gcatttgaaa ttcttgctcc tgatgtcaat aaatgagtat attcatcatc
    21061 tatattatca ttaaatcctc tatatgttgg tagtgcatcc agcccaaaat ctttatattt
    21121 ttcaataatt gtagatttta attcaaacct agaagtgcta gtatcatacc cttctcttgt
    21181 atatgaacct actatatatg gcttaaaatc tttacatttt aatggtaaat cactttcttt
    21241 aagtttatct acatctacac atgtattttt aaacatatgt cttacacttg cttcataacc
    21301 tgcttttaat aaatcatcat ctatattcat agcatttgct aaatctgaaa gtatttctac
    21361 atctgatttt gaatcgtata atttatcaat aacttttttg gtatatgtaa tataccctcc
    21421 tggataactc ttacattctt ctctctcaaa tgatgtacat gcaggtaaaa gtatatctgc
    21481 atattttgat gtatctgtca taaataaatc tatattcaca aaaaaatcta cactattcaa
    21541 cgctttaaaa agtctccctg aattaggaaa cattctagca tttatcccat gacaaaacaa
    21601 agctcttatt tcatatggtg tcttttcttc tatttgccta ggtaaatcca tagcttgaaa
    21661 ttgagtcacc atttcattcc atagaggaaa tctttctcca ccaattcttt catttatatt
    21721 tttaggtaga acttctttta caaactcttt ttctagtgtt tggaatccac ctatcttacc
    21781 agcaaagtaa tcttgttttg gtatgtttcc acctattcta tcataattac ctgttatagc
    21841 ggataaagac atcattgctc tataattttg aaatccattt tgatgatgaa ctattggagc
    21901 tgcactttca tttatacaaa atggaccttg tgacaacatc tcaacagctt ttactatatt
    21961 atctttagaa actcctgtaa ttctacttac agtatctaaa tcaaataatt ttacatattc
    22021 tttatattca ttaaatccat gtacatgctt ttctatgtat tctctatcta ttaaatcctt
    22081 ttgtataaat agattcgcca ttccaagagc taaagctcca tcagttccag gtttaattct
    22141 taaatgtaaa tctgctagtt tttgagttgt cggtgttatt ctagggtcta caattataaa
    22201 ttttagacct ttttctttta attttattag attcacacta tttaaaaatt tagagtagta
    22261 tggattaaat ccccacccta aataagtttt tgcattctcc atatcttgca ttgtaaagtt
    22321 tcttccagta gcaacatttc cagccatctg tgctgatgtt gaacatgaac tagattctgt
    22381 accataatta ggtgaaccaa atgaagatgc aaacctttgt aaaaaaggtc tataccactt
    22441 tccataaccc gtaaaaaaag ctacatgctt tgctccatac tcagatttta ctctatttaa
    22501 tttttctgct atttctctat aagcttcatc ccatgatatt ggtttaaatt ttccttcacc
    22561 tctttttcca attcttttta gaggtgtttt tattctatct tctctataga tatattctct
    22621 attgcaaaga cctttggtac ataacaaccc tttattcatt ggatgttctt ttgtaccttc
    22681 tatttttatt actttaccat ctttaacata tgcatcaatt ccacaatgta ctcctggcga
    22741 acaaatatca cataaagtcc tctttatttc tatacctgtt tccttacagg gtattttagc
    22801 tttaagttgt ttataactat ccatattaac attttccttt cccaataata aatacaaatt
    22861 attatactta ttatacattc tttttattca aatatcatac tttatatttt atacagtgta
    22921 atttctaaga atatttttaa taataagatt ttatatttat taataatcta tttatataat
    22981 tatttttcat tcatagttta taagataatt caataaaaat ctaatagtaa attgttattt
    23041 acacatatat cgtgatagat aaaagctatt catatctgcc ttaattttag tcttaaattt
    23101 agagtgtaaa ttgaatgcat ttagattata atatatacag tgaggtaagg tgaataatat
    23161 gaaaatagat atgatatata aactaataag aagaaataca gaaccatcaa gatggtcaag
    23221 aggtgtaaaa tattatacta atcaattagt tgattatata gacatagata ttgatgacct
    23281 acaaaataat ctgttgacat ttcgtggtgg agtcaattct gaagataatt atagctttta
    23341 ttttaattca ataactatag atataaagca ctttaagata attgaaaatg attgtagttg
    23401 cgctgactgt caatcaaagg gcaaaagtat ttttatatgt aagcatatag ttgctattgt
    23461 gataaaaagc ttaaaacaaa taaaaaataa aaaagatgtt cctcctattc taatagatat
    23521 attaggtgca gataaggata agctttctaa tacaaattct aaaaccagct tagatttaag
    23581 caagcaatta ctttctttgt tagacaatac taaaagagaa agggttaatt tagatgtatt
    23641 gataaatgtg gattcaaata aagcaattgc tgaatttaaa ataggaatta ataaaatgta
    23701 cattttaaaa aacattactg aatttgcata ttcaaaactt aatggatatg aattagattt
    23761 tgggaagaaa tttacttaca accccaacac tcattatttt gctgatgaag atgagaagtt
    23821 agtagatatt atagaagaat atgggacaaa tctttcatac aacttttctt catcacattc
    23881 aaaaaaattt atggagataa atgcaagctc tttaaaacaa tttttaaatg ctattaagta
    23941 caaggatttt acccttattt tttctaaaga ggaatatcat ccaaagatat taaatgatac
    24001 tctacctgta aggtttgatt ttaaaaatat agaagataaa atagtcttat attctaaaga
    24061 ttcactacct gttccactta ctaaaaaaaa tgatgtactt ttatatgatg gcaatatcta
    24121 tttattatca cataaaaaag ctcatgatta ttcaaaaata tatcaaatat tatcaaagac
    24181 taaagagtta aaatttgata aagaggattc taaggatgtt ttaggattgc tagttcctag
    24241 attaaaatct atatctcaag aagttcattt agatgataac ataaaaaata atataacaaa
    24301 agattttaaa tctgagttct actttgatat gattgatggc aacatatgtt gtgatgtaaa
    24361 gtatatatat gatgatgaag ataaaaaatt tgtgctcccc aacatacaaa aggaagctac
    24421 tattgaaaat aaacttactt cttcacaatt tacaaaggaa aataatcatt atgtgtttaa
    24481 aggaactgac catgacctat ttacattttt agatttacaa ttagaatctc taaaggaatt
    24541 tggagatata tattattctg agaagtttaa attgaaaaaa atatataacg cttcatcaat
    24601 tcaagcttca atcaatcaga ctaaccagaa ttacctagaa tttaatttta atatatctga
    24661 tataaatcca aaagagtaca aggatatttt gaaagctttt caagaaaaac gtacttttta
    24721 taaacttaaa gatggaaact ttatagattt atcagaaaga gaaacaaaag atttttttga
    24781 attagttgaa aatctagata taatggataa atcaaaaaat aataaaattc ataaaaataa
    24841 agctctatat ataaatgatg taatacgtag taaaaattta aagtttatag atggtaaaaa
    24901 agaactagac agtatatgtg aaaaatttag aaattttgat agcataaatt tagaaattcc
    24961 cgcaaattta aatgcaaacc ttcgtgacta tcaaataaat ggcctcaatt ggtttaaagt
    25021 tttagattat tataaatttg gtggtatatt agctgatgaa atgggtcttg gtaaaacaat
    25081 acagactatt gcatttttat tatcattatc taataaaaaa agtcttattg ttacaccgac
    25141 atcactcatt tataattgga aaaatgaatt tgaaaagttt gctccagata taaaagtttt
    25201 attgatacat ggaaataaaa gagatagaga aaaatgtttt atggaattag aaaattttga
    25261 tgtaatactt acaacatatg gtactcttag aaatgattta gacaaatata gtgaaataaa
    25321 gtttgattat tgtatattag acgaagctca aaatataaaa aatccagtgg ctttagtaac
    25381 tgagtctgta aaaagtataa atgcagaaaa taaatttgca ctcactggta cacctatgga
    25441 aaataatcta ctagaattat ggtctatatt tgattttata atgcctggct atctatatag
    25501 taaagcaaag tttcaggaat tgtttataaa taaagaagat aatgttaaaa acctgaaaaa
    25561 attgataaaa ccttttattc ttagaagaag taaaaaacaa gttatgaaag aacttccaga
    25621 taagattgaa aaaaactttt ttgttgaatt gaataaagag cagaaaaaga tatatagtgt
    25681 atattcaaaa gatatacaag ataaaatgaa agataaaaat ctaaagaaag ataaaatagt
    25741 tatattctct tatttaacta aactaagaca actttgttta gacccaagta tagtagtaaa
    25801 agattacaat aaaaaaagtt caaaaattga aacatgttta gaaatactta gggatagtat
    25861 aaacgaaaac cacaaaatat tattgttttc acaatttact tctgtgctta agaacataag
    25921 taaggaactt gataagtata aaattaaata ccattatata gatggtaaaa ctaatgccaa
    25981 agaaagactt gaacttgtag atgagttcaa taatagtatg gataaaaaag tttttttaat
    26041 atctttaaaa gcaggcggaa ctggtttaaa tcttacatct gctgacatgg taattcactt
    26101 tgacccatgg tggaatccat cagtagaaaa tcaagctagt gatagagctc atagatttgg
    26161 tcaaaaaaat tcagtacaag ttataaaatt gattgctaaa gggactatag aagaaaaaat
    26221 aataaaatta caagaaagta aaaaagagct tataaatcaa tttataaatg gagaactttc
    26281 taatgaaggt gtattaaaaa gtctatctga tgaggagata ataaacttat ttaactaaat
    26341 tatttaatcc tacagcttaa ctatatgaat ttgttctaac atttatatag ttaagctaaa
    26401 atatctgaat aaataaaatt taatattgtt atttaatccc aactttacaa tctaatgata
    26461 tctctttcta tacatattgc atatacaaat gtaataactt gactattaga atattttgtt
    26521 ttaacaatcc tatttcatca taataatgaa gtatatgtac actcactttt gtaagttttg
    26581 caatccattt tacagttttc attattgtaa attttggtta aattattcct ctaaaaattt
    26641 ctttgctaca tttgaaaaat ctaatccatt cgataaaatt gcaggatgac cacctttatc
    26701 aaacaaatac attttaccat ttttaatctt ttcaagaagt aatgaaaaag tattttcaaa
    26761 aaaatcacta gatattagag atacaaactc atcttctcta cttcctgtta aaagcacctc
    26821 tggttgcata gtttctagag gcttatgaaa aaactttcct atagttttat aatgttcaaa
    26881 aatagcttct gtatcattat ctacaacttt ttcccagttt tctccttgat tataaatata
    26941 aaaagctttt gcaccatcat cttgcttaga tgcttcacgc tctattttca cattttgtac
    27001 aaatgactct agaggaactt ctccttcaaa actatctgca attaccttat tcactaaatc
    27061 aggtctctca agtgcaacat ttaatgcaac aagagctcct ccactactac caattatgtt
    27121 tactttttta tagttcattg cttctaaaaa acatatcact tgcatagcct catcaaacca
    27181 taagtcagca gaaaatttat cgaccatttg agattttcca tgacctacaa aatcaattaa
    27241 tattacttta tattcatctt tataaaaatt gattatatca ttaaacatct tggaagaggc
    27301 tgtatttcca tgtaaaaaaa gtaatggtgt accatcccca atttcattat agtagcactg
    27361 tttgtcgtta tagttaaaat atgccatata tttcccccct ttaatatccc tataggtata
    27421 tatttattac ttatatttaa aatgactatt cccttagcca cttaaaaata gtataactta
    27481 gaatgtagat aaaatcaaca ttccttgcta atttatctat tgtttgtcta atttattata
    27541 atttaacttc tgtaaaattt cttttttgta cgaaaatatt ccttccattt acaacaatca
    27601 ttcaaatgaa gtataacatg acgagtagga ggcataagca aaattccagc aatatcttta
    27661 ttcccccaaa agtccaacaa ccaaatagaa tcttcatgct ttattactcc tccagtcacc
    27721 aaaatccttt ctaagtcaat tggagagacc tttcgtttca tatcttcagc tttcaaatcc
    27781 ttaacaactt ctattgtgtt ttttgcaact tcatttcgat aacaaagcaa ttcatcaata
    27841 ttgactaaat tatcgtatat ctcttttcac tttaaccatt tttttcttta taggtatctc
    27901 cttatatttt tttaatatca aatctccctt ataatttaat atatctacat atgaacataa
    27961 atcttgaact tcaattacac ctatatcatc attagttata ccttttatat tactaaatgc
    28021 accaactata tctaaaactc ttattttctt cttcttacca gcatttaaat ataatttaac
    28081 aacttcactt tctatattta gttttatatc tttacttttg taagaatttt tatcaacttt
    28141 ttttctcttt gatacttttt ttaggattcc ttttgaatat tcttcaaaca aaactttgcc
    28201 atgtgtaatt ctactttttt ctatatcttt taattcattt attttatatc ctatatacgt
    28261 ttctatattc tctatatatt tttcatcctt ttcagttact atagtaattg cctttccact
    28321 atttcctttt ctcccagttc tacctattct atgtatatag ttttctttat cttgtggcac
    28381 atcataattt attactaaag aaatatcatc aatatgtatt cctctggacg ctacatcact
    28441 actaactaat atattaaatt tttggttttt aaaatcctta attacaaaaa ttcttctttc
    28501 ttgtgataaa tctgcatgta actctcttat taaaaaaccc tctttactca tcttgttata
    28561 taatttagat actttctctt tggtattaca aaatattatc acactctttg gattttcgct
    28621 gtatattaat tcttttaaaa ggatgtactt ctctcttcca tttgccttga ttattttgtc
    28681 atctatttgt cttgtttttt gattagtatc gctctcattt tcttctatat ttataacact
    28741 gtaatctagc atatattttt cacatatata ttttatctct tcatctattg tagctgaaaa
    28801 aagacttact attttctcct taggtaaatt taataatatt ttttccattt gttcaacaaa
    28861 acctttatta aacattttat ctgcctcatc tattactaaa tactttacat tttccaactt
    28921 aatagaacct ctatttatat ggtcaagtat tctgcctgga gtagctacaa caatatgaac
    28981 cctttgtttc aattcagcta tttggtcttt tatagattgt ttgccaaata tagcactaca
    29041 tctcaccttc tttagtctcc ctatatctga tatctcatct tttacttgca aggctaattc
    29101 tcttgttgga accactataa gagcttgaat attattgtaa tctacattta tattctcgca
    29161 taaaggtatt gcaaaacttg ctgtctttcc acttcctgtt tttgacctaa ctactaagtt
    29221 ttgacctttt aataattttg gaataacttc tctttgtact ctagaaggta tattatatcc
    29281 taaactcttc aatgacttaa gtatcttttc atttaactta aatttttcaa atgtatattt
    29341 catatattac caccttatta tatttatctt atctatatat ttttctacat tatattatta
    29401 taatacaagg ttctactatt tttatattat ttattagact gaagataaaa gtatatactc
    29461 tataaaccta tagtttagta gcaaattaat taaattttta tatttaaata cctccttaaa
    29521 tatactgata aatcaatatt ttcaaggagg tatctcttgt caataatcaa actaatctat
    29581 cttttgaaag tttaaattat actaatacat tgtattttta tttatatcta atattaaaag
    29641 gtattaatca atacctaaat caccataatc tcacatattt atatctttat tcaatatacc
    29701 ttctgtaatc aatcgtgcta tataatcata acctgattca tttgctttgt tacaatcatt
    29761 cacattatca cagaaaaaac tttcaatctg tattgcaact ggatttgtat ttctcaatat
    29821 atataaattt tctctttttt tagctcctct attttcaaat aattctccaa gtctattaga
    29881 tactctttta gcatattcta atccttcagt gccatagtaa agcacttctg taccacattg
    29941 tgttccatca gctttattta aatgtagctc tactaataaa tcgtatttac cactgtttac
    30001 ttttggaact ctatagaaaa attcttctct ttctgacata aagtgccttt ctggacaaat
    30061 tattacatct actgtattac cttgacttat aagcatctca gctaacatag gagctaattt
    30121 tttattataa ttgtattcat caactatacc atttacacct gtacttttac caccttttag
    30181 tatactatga cctactgtta tgcatatttt catttacttt tttcaccttc ttttaagcca
    30241 atttttatat aatagtaata taattttaaa gttattacta ataataatat attaattgaa
    30301 gaaggtaaaa gttctccgtg attatcattt ttttaacata tttgtcttat tttatcataa
    30361 atctatattt tttaaatatt atactatact tattatttat aattgtttaa ttaatcattt
    30421 atatatatga taaatatatc aatatctatt ttcctttaac caaatgctat tttaataagt
    30481 ttaagtttta gctttaaaat acttaataat acaataaaag tgatgtattt acaaataatt
    30541 cttctggatt taattcattt attgatgtat gttcaatttt tatatttata tttttcatat
    30601 cttcataaat aattccaact ggagaacaaa tgaaacaaga aaatccaaaa gtttttgtta
    30661 ttttttttac cttattatca ccaaaactta tttgcttttt acaatcgttt atattttcat
    30721 tgttattttg tatatcattt ttataatact tatctttttt aatgtcatta gacttattta
    30781 ctgttttaaa attactccta tttttacaac tatagtctat ttcaacttct atatacccaa
    30841 aaactatcaa gttacataat ttcaaattac tacctttgtt tataagattt ttcataggtt
    30901 taacatcaaa tattttacta tttacattta cttttaatat atctcttaga tttttaggag
    30961 cttttaaagt attacttata ttcaattgtt tgaatacaat tttatttaca ttagtataaa
    31021 ctctattact ttctattgat attcttgttg ggaatttatc tagattacac ttataataat
    31081 agtatatatt agcactattc tttataatcc tatgtgcaga atttggtaaa actacactct
    31141 taaaagatat tattttttta caacttgcat ctattctccc tatgtaaaaa ccttgctgtg
    31201 ggtctaatcc acgttttata atgccattaa cttttaccgt attatttata aactctatat
    31261 atttagaaat ataatctttg aaaaatatat ttccagtttt gtacctactt gtatttgtaa
    31321 caataatagt gtaggtcaaa atctcaaata cagatgcaca ttttttatca acatattttt
    31381 ctacttttat aatacttcca tttgcatcat ttgaaaatac atcattaaaa gtagttttcg
    31441 ttattctcat tgcatccacc tttctataat ttaaagatta ctctatcttg gaactatttt
    31501 cataacttat aattgcagta acactaataa ataaattatc atctaaaata gatgaagtaa
    31561 tatcttgtat aagatacttt aaattaattt tatctttatt ttctatcttt ctaggcattt
    31621 gtataaatgt actaaagggt atttttaatt taaatgtatt ttttttacta gaatttctat
    31681 ttcttttatt gcctgcataa tctaatattg catcaatatc tatatcacca actaaaatca
    31741 acttctttcc tgtaagttgt tcatcttcta atgatataca ttctatagta tcaacaagac
    31801 ttatattgtt aatattcata ttgtaaacat atgtctctaa tgaatttatt acagtttttt
    31861 tagaagctaa tttaaaattt ttatatgtat taaattgaga taaataaaga gtcttttcta
    31921 gtttttcaca tctttcaagg ttgtatatta ccttattatt ttcatacata atcgcatcaa
    31981 tctccctgta tctatatatt aatactattc ataaaaatta tttcaaatta ccatttttta
    32041 ttattcacta tctagttgtt atttactttt aagaaagaat ccttttttac ttcattgatt
    32101 tcaatttaca agtaaaagtc tttctgaaaa aaaaatatat atatctctat tcactttttt
    32161 ataagtaatt ataattttta tagactaacg gtcagcctta agggaaaagg tgttctttaa
    32221 gtgcagaatt tagataaagt aaataatcct tttataaata attccaagtt ttaacttaaa
    32281 taatttgatt tacagtataa agtaaatttt gaaagataat gatatcgatt taataattac
    32341 aagtaaaagc atgtcaaaat aaggctatga ttttaaaaat catagcctta tcaataaaaa
    32401 tttaatcaaa gttacatttc actttgaatt tcactgtcta ttaattgaag attatactgt
    32461 tgaattaatt ctattagacg agctgcatat atactattgc cattttcatc cttcgcagta
    32521 ctataacctg ccttttctaa tgctttagct tgatatatat acgtttttgc atcaaataca
    32581 ccattgtttt tatacctttt atttgtggct aaaaattttg catggtcttt tatagattca
    32641 tttttatcat catatattct aaatttatca tctataattg tatctaaatg ttctttcgtt
    32701 tctaaagtca ctgacttgcc tttccaataa gcgtcagcct ttataccaaa tagattgtta
    32761 tattgttttg ccaaagttga cttgccccag ctagattcta ttatagcttg tgcaatagtt
    32821 atagatggaa gtattttata atccttataa ttttgtattg cttctgtttt aatttcatca
    32881 ataaacttca tatattttgt atcagacttc aatctttctg gttttatacc ataatcctta
    32941 agattgtcta tataattatc aaccaatctt ttttgtctat tactaaattc taactcatcc
    33001 aaaatatcac ttaacttatt tattttatta tttttagaaa aattcttaac aaataaatct
    33061 gatacttctt gtatctgtga atccttaacg ttttttaagt tatttttatt taacacagca
    33121 acaatggaag ctacatactt ccagttaact tgtgcattat ttttacttgc taaatcagca
    33181 tattttatat acttactgac atttatatca tcctttttta tctctctaga tgaatattcc
    33241 ttcactaata cacctattaa aattgatatt atcagtatta taacaatgaa ttttttattc
    33301 ttcataaata ttgtcctccc ttatactatc tgctgaatat aatatacctt acttttgtga
    33361 catattcttt acgaaatttt gaaaatttta tgaagattta tgaaatatat ttaattaaaa
    33421 gcactactat tgttataata tatagttttc tatcacacaa aatagttaaa ataaataaat
    33481 aattagatag cttattttaa ctatttatat aataaaaata ttattaaatc tatttatcaa
    33541 tttttataca tttttctaat atatattttt tcccatatac aataattttt attggtttac
    33601 cttttaaatt ttctatttta attaaatcac tacatacatc tacattaata atattatctc
    33661 tataatttat attgaaagaa taatttttcc actcttttgg caacttaggg tcaaaagata
    33721 gagtttcatt ccatgttctc atgcctgcaa atccatgtac aatggaaagc catgaaccag
    33781 acattgaagt tatgtgcagt ccatcatttg tatcattatt gtaattatct aaatcaagcc
    33841 tagctgttct tgaatataat tcataagcct tttctaggtt atctatttct gaggcaataa
    33901 tagaataaat actagaagat aaagaagatt catgtacagt atatttttca tagaagtcaa
    33961 aatttctctt tttttcttct ttagtaaatc tatttccaaa atagtaaatt ccctgtaata
    34021 catctgcttg ttttataaaa cacgacctaa gaatcttatc ccaagaccaa ttttgattaa
    34081 gaggaaaatt ttcttttggt aaatccttta cttctacaaa ttctttatct aaaaaattat
    34141 cattttgaat tattatttgt agttcctcat catacagcag atacatttta tttgatatta
    34201 ttttccaaaa ctcaacttct tccctagtca cattatttct gtcaatacat tcattacact
    34261 ctttctctaa tcgtaagata ttttctacag cataatctaa acaccattta gctatataat
    34321 tagtatacca attattattg atattgtttt catactcgtt tggacctgtt actccatgta
    34381 tcatatacaa atcttttttt gtagacaaat gaactctact tgcccaaaat ctagctattt
    34441 ctattattac atctattcct ttttctttta tatatttata gtcacctgta taatttgtat
    34501 agttatatat tgcatatact atacttccat ttcggtggat ttcctcaaat gttatctccc
    34561 attcattatg acattctact ccatcaaatg ttaccattgg atataaagca cctttaagac
    34621 ctagtttttt tgcattatcc tttgcctgtt ctaactgatt gtacctatat tctaaaagat
    34681 ttctagttac ctccttatct gctacaccta gatatactgg aacacaaaac gcttctgtat
    34741 cccaataagt agctcctcca tacttttcac cagtaaatcc ttttggacct atatttaatc
    34801 gcgaatcttc tccataatat gttgaaaata gttggaataa attatatctt ataccttgtt
    34861 ggctactttt atctccattt atttttacat ctgcactttc ccatctttta ttccataact
    34921 ttatatgttc atttaatata tcatcataac ttttagatag ttctctattt aaaatgtctt
    34981 cacattttct taatagctca ctttccttat aatctctagt tgaggttata gatacatatt
    35041 tttctatact tgcaacctca ttttttaaaa catccattgt tatcgaattt tcacagtaat
    35101 tataatcact ctcatgagat acagcttcta catcaccatt tgtcttaata tacatcattg
    35161 aacccacagt gaatactggt gtattaaatg cattctcctt tgttcgagaa agaatactcc
    35221 ctttatattc taaagaactt gaagaaattc cattccaaaa cttttcctca tagtttgaat
    35281 cttcattttt tatatttgaa tctaaatatg gtacaaattt tattttagta ttagaattta
    35341 atgattttat actgtattta attactgcaa gttccttaac agatatactt aaaaacctag
    35401 taaccctaac ttcaaatttt ttatcattta tatttacaat aaacctacga tttaaaatac
    35461 catttttcat atctaattct ctatgaaaat cttctacttt acattttgct aaatctaatt
    35521 ctacatcatc tatgaaaatt cttacaccta tatagttgac tgaattagga attttaccaa
    35581 agtattctgg atacccattt ttccaccaac caacacgagt tttatctgga aaccatactc
    35641 cagctatata agaccccttg tgtgtatctc cactataatt ttcctcatag tttcctctca
    35701 tacccatata tccattgcct atactcatta tggactctgc taatctattt tctttgattt
    35761 caatcttatc ttgtataatc ttccactcat ctacattact aaataaacat ttcatataat
    35821 tctcctaact atatactcat tatacttttc ttgtatatat tcaaacttta attgatttgt
    35881 tgaatctaca actaaatttg ctttttttaa gttttcataa tttccaacac caacagaaaa
    35941 catattagct gagtttatag cgtctatacc tgcacttgca tcctctatcc ctatgcaatt
    36001 ttgtggattt acattaagcc ctttcgctga cataagaaat atctctggat gtggtttatt
    36061 gtttttacat tttcctgcat cagctataaa atcaaatttg tcacttatac ccaaatgatt
    36121 taatacattt attgcattct tacttgcaga agatagacct atctttatat tattagattt
    36181 tacatcaatt aacaagcttt ctatgcctgg caaaatatca tttgaagtta tctcatctat
    36241 caatgataca tagtaattat ttttttcttc agccattctc actttttctt cttctgaaaa
    36301 tgaatatttc ttatttccaa attctaatat cctgtccaat gactccattc tacttatgcc
    36361 ttttaaagat tcattaaatt ttgtgtctat atctatccca actttatgag ctagttttct
    36421 ccaagccata tagtgataat atgcagtatc tgtaattaca ccatctaaat caaatataaa
    36481 tgcttcaatc attcttattt cctctttcta caagaaattt ttagactaat aatcaattta
    36541 ttttctatct tgtatttaag atattattta taaaattatc tactctaact cagtctttaa
    36601 tttaaaatct actttcaatt cactcacttg tagaccatat tttttatcgt ttataaagac
    36661 ttgtttaaac tgtataataa tttaacatga aatctaaaat aaatactttt ttgtattatt
    36721 ttaaaataat gaacttgtat ttctctaaca ttagttcttc ttttaaatca actatttctt
    36781 cttcatataa atcttttact tttttatttg ctaaataatc tggtaacgtc aaaattatat
    36841 ttttagatga attatttatt attatagaaa tagattcttt tttcaatata atcgttccat
    36901 tttccttatc tgctaacacc cattcatttg atatagacct aagttcttta ttttctttac
    36961 gaagtctaat aatcttcttc ataaaatcaa atatatcctt attccatttt tcttcattcc
    37021 attccataca ttttctttga ccttcagata ttgaacttaa ttctccttcc attccgattt
    37081 catcaccata gtatatacaa ggacatcctg tttgtacaaa cataaacata tatgcaagtt
    37141 taaatctatc aatatttcca ttagcataag tcaatattct tgtagtatcg tgacttccaa
    37201 gtaaattaaa aataacttca ctaacttgta ttggataact taccattaca tcatttatca
    37261 tatacttaaa ttcttcggcg tttatctcat ctgtacaaaa gaattttttc atggcttctg
    37321 acatcaagta attcataact gaatcaaatt ggtcacccat taaccatggt aaactaccat
    37381 gccaaatttc tcccaatata taaatgtctg gttttacttt tttgacttct tctctaaact
    37441 ttctccaaaa aacatggtct acttcatttg aaacatctaa tctccacgca tctatatcaa
    37501 attcctgtat ccagtacttg cctacatcca ataaatattt tattacttct gaattttctg
    37561 tattaagttt aggcatatat ttttcacacc caaaggtttc ataaggtata tttttttcat
    37621 ctatttgttc tattggagta tcaattttac tcatatcttt tatataaaac cagtttttat
    37681 atcgagaatt ttccttattt tgaactacat cttgccactg tttagaataa tatcctatat
    37741 gattaaaaac agcatccaac attattttta tatttctctt atgcgcttct tctattagtt
    37801 tttttaaagt ctctttatct cctaatgtag ggtctacctc catataatct accgtatcat
    37861 atctatgatt ggtttttcca attgtaatag ggcaaaagta aattccgttt attcccaaat
    37921 cactcaaata atctaagtgt tctatcacac cttgtaaatc tccacctgta aaattatctc
    37981 tggttggaat agctccccat ttatctactc cttctgggtt tatagacggg tcaccatttg
    38041 caaatctatc tggaaatatc tgataccaaa cagtatcttt cacccaattt ggcactttag
    38101 gtatatctat ataatttaaa tatggatatc caaaaaaatt acctatttca cataattcct
    38161 tttcatcatt ttcatttccc aactctatta ttcttttttc tgtaaataaa agtttttcct
    38221 cttgaccttc tattataaag ccatatcgtg agcgtttatt taaaggctta cacttagcta
    38281 tccaatagtc aaataattca gtttctactt ctttactcat tactatattt gttccaccag
    38341 accaaccaac tccagatgca tttaaatttc ctcctcctgc acctccttta tcccacacat
    38401 attggtctcc tattcgtaaa attactcttt tcgcttcatt ttttttagtt ctaagtctta
    38461 tatgtagtgt ttctctatca taaccatagg cataattgct cattggtata tgtaatatag
    38521 cttcttttgt taaactattt tgaattgttc ctttgatttg attacttaaa gttatatttt
    38581 ctttattttt attagacatt ttaaaatttc cctcctttat aataatttat ataatctaaa
    38641 gataggttaa tatattttac tattatatca caataaaaat atataatagt aaaatatatc
    38701 aacaataaac tattcaattt aaaataagct atactattta aatttaattc tatttagtta
    38761 ttttagcaaa ataaaaacct ctagtatttt tctagaggat acaatactat aactattaac
    38821 tttttaacta tctattaatt tacttcaaaa cacactctaa gctatattgt tagatttaac
    38881 tttttctata tttacaaaat aggtttctct ttctttaaat aaagatacat atttaaagtc
    38941 aagatactta agcatatcat aggccacatc aaaatctttg catatatctt ctaccctatg
    39001 agaatcagaa cctacagtaa ctataaatcc tccaagttct ttatatcttt ttagaatatc
    39061 ttcatttgga tgtatagcat ttagtccata tctataacca gaagtattta gctctatacc
    39121 actcccatta ttgattattg actttaagac ctcatcaata acatctttaa agtcattgta
    39181 tataactcta ttatctgaat atattccata cctagatata taatccaaat gaccatatat
    39241 attgtaatct ccaaattcac gattagtttc aagtatgcta ttaaaatatt tataatacgc
    39301 atcttctttg ctaagacctt taaaatacgc ctttgatgga acaggtacat tgtcaattgt
    39361 atgagttgag cacaatacaa aatcaaaagg attagaattt attatttctt ctatttcatt
    39421 ttttagatgt tttctgtaac ccacttcaac acctagtaat aactctatgt cctttttata
    39481 tttttcttta aacttattaa atactggaac atagtcatta taatttatgc aaaatcctct
    39541 atcttcatca tgttctaaat ggtctgtaaa agtcaaatat ctaacaccaa tacttatagc
    39601 tttttttatt gtatcttcca tggaatcctt tccatcactt gaaaaattag tatgaatatg
    39661 attatctatt aaattcatat tatccctccc tttattttat ctatcttaat tatacaacaa
    39721 gtttattgta tacatttgtt aaaagaaaat tataatggtt aaattttatt tacatacttt
    39781 tatttttaca aaaaagagaa gcacctattt ctgattttag aaaatcatta aggatacttc
    39841 tcctaatgtt acttttatat acttcaattt aatttttaaa agtcttaatt ttgtaataga
    39901 gtttagctgt tatatgtcca atcatataaa aagctgtata aagtaaaaca tatatatatg
    39961 cagaatcatt taaaaatata tacattaata ctatataagt tactaaagaa acaataagag
    40021 ataaaatcca attagtctta tttaatacac aaattatccc ttgtatcaaa aaagaaattg
    40081 gaaaaatcaa aaccattccc acaacaaaaa tacttttaga ttgaatatct ggaatattaa
    40141 atatatctgt agcaaaagtt aaaaacatta gcaccattat gactgtagga aatatgatac
    40201 taaaaatatt actctttttc ataataatca atccttattt attggatatt tgataatctt
    40261 caattatttt gttgcctcaa tttctcccat cattcttact aaatcttgtc catattgacc
    40321 tccagcccaa ttattagata aactttcaac tgttttagcc ttaccaaata aagatttttc
    40381 atgtctaggg tctactggat ttgaaagtgg gtaaccatct tgtcctgcat ataagcataa
    40441 atgttgaatt tgagctaata ttccttcttc ccaagtatca aatcttgaat gggcattctt
    40501 atcagtatca gaaccaccta cagaagtttt aagtccacaa ggattcttaa atgatgcatc
    40561 taatactcca ccaaaattac aaaaaccagt ttcttttgca gattgagcta ctgccaaaac
    40621 aggattaaca ccttcctgaa cagcagtatc atataatatt ggtattaact ctataaataa
    40681 atcattagct tttttagatt ttgcccattt taagcacgct tctaaactag ctgttggctg
    40741 acctaatatg cttgtctcat ttttcatagg tgactcacct tttgtagacg aatcgccatt
    40801 attttgtgca gcagaaacac acttattata cacactgtca cttattgaac ctaatctagt
    40861 aatcttatct gctcctgcta atatagactt atcactactt tctgacacca atacaattgg
    40921 attttcctta gcaattgtag aacctgtaag tgcatttact aaatcatatc catcactcaa
    40981 ataaaattct gatgcatctg gataaaactc ttttataact ttcttatttg tatcatatct
    41041 atctgaacca ccaagtcttt tagcattagt tttattaact aaactagtgc tcattgatat
    41101 actcccacct actgcatatg tttttacatt gcttgttgaa aaaggcacac tctttccatc
    41161 tgtaagtact ataggagcta tatctcttac tgatacgggt gcagcactta ttgtatctgc
    41221 ttctccttta tatgcattag ttaatatcac ttcatcaact tttttgatac catttacctc
    41281 tttagcaaca ctataactag tctttattct gtcatctcca cccaatctag ttacctgtgc
    41341 ccctgtgttt tttagttcag tttctactga cttacttatt gataattctt tacctattat
    41401 gtatatcttt ttaacatttt ttaatctttg ttttgtttca tttggtatct tatttttttg
    41461 tgcaagcaaa attggagcat caacagcacc tgcaagacca cttgctgaaa gaccatctgc
    41521 tatagaatta tccatattta ccataattgc tgtatcataa ctctttttat ctgctattaa
    41581 tccagccgtc tcatatatat tgttaccttt aattgtatct gatgttaatg catctacatt
    41641 aggtacattt attagaaata tagctaatgt taaacctaat gctaaaactc ttctaattgt
    41701 tctcatattc ttcccccttg atatatcaag tttaattcaa aaatgactat aacatagtat
    41761 tacatctacg ctatagtcat ttattataat ttaataatta tatatttgtt attatatcat
    41821 aaattacaaa aagtttccat aatattgtat agattaaagg aaaaatttac attttagtta
    41881 caatttacta gatttttgtt ctaatgtacc tatatttagt aacaatttgt aataaaaatc
    41941 gatatctata ttacatattt aattcactgt tttacaaaat gaaattttat tgtatacaat
    42001 aaatagatta tatgtttaca taatctatat tatttttaag taaatctttt atcgatatta
    42061 ttaagaatat atattacatc aagtttatta cgtgcaaacc actatcaact taaataccta
    42121 aggtaacact tgaagtagta gattcttggt aacaataatt attgctatca ttatcttttt
    42181 ttaattaagt atttactatt tatatatcaa tctacttttc acttttaatt taattctaat
    42241 atttttttat atgttttatg atatataatg tgatatattc taattaatga tattttcaag
    42301 taaaaaaatg ttactctatt ataaggtgat agtatacttg aaaataaata aaacacttaa
    42361 ctttatttaa ggagatttat gatgagtaac aaacaaggtt ctaacatcaa agatgtaaaa
    42421 attaaaaata agttaataat attgaaatta ctttctacaa atacacctat gtccagagtt
    42481 gatttagcta agtctacagg acttactaaa atgactttat caaatctagt tactgaactt
    42541 attaatgaaa atatgattag ggaaatagag tcatcaactt taaatgcaca ttcatcaggt
    42601 cgtaaaccta ttttattaga tatttctaat atatcgcctt gtatttgtgg aatcctaata
    42661 agaagaaata tatgtaaggt aattatttca gatttaaaag gtaatattgt aaaacaactt
    42721 tctgaaactt accctaaatt tctatcaaat gatgttttaa aagatataat aaaaagaatg
    42781 tttactaaaa taatgaaaat caacaagaga gatataattg gaattggtat ttcttcaata
    42841 ggtccagtag atgatataaa tggtaccata ctaaatcccc cagattttgg aaatgtatca
    42901 aacctaaata tagtagattt tataaaagaa atgtctgatt tgccaatatt tttgataaat
    42961 gatgctaatt cgggtgcatt agcagaaaaa atgtatggtt taggtaaaaa tatatcaaat
    43021 tatatatacc tacacataat gaatggtatt ggagctggtc tagttctaga aaataaactt
    43081 catactggca acctaggaca aagtggagaa ataggacata catcaattaa ttttagtgga
    43141 ccattgtgca gttgtggtaa caatggatgt ttagattatt atacaagtgt cagtaatcta
    43201 attaaaagaa ttgaatcatt gagccatatt tatcctaact ccccattaat taactgtaaa
    43261 gatttttctt tagtcaagtt aatagatgag gcaaataata aagatagtct tgccatgttt
    43321 ttgcttgatg aattttgtac atacgtatca tatgcattag ttaatacact tacattgatt
    43381 gattgtagtt ctataataat aggctatgac tttaatatac ctggtacatt tatagaaaat
    43441 acattattaa aaaaattgac tgcttcagca agtttttcta aatataaaaa aataagtgta
    43501 aggcattcaa attttggagc aaatgcacca ttaattggct ctatagccat tgtaagttat
    43561 aattttttta atggtagtat aaatttttat taaatatgta aaatatttaa acacttttat
    43621 tgaatatttt tccatttaat attattatat tttataagag catttaaaat ttggaggtat
    43681 aaaaatgatt tcagctaaaa tggaaaaatt acttaatgag cagattaacc atgaattata
    43741 ttctgcgtat ctttatcttt ctatgtcttc ttaccttgaa gcagaaggac ttaaaggatt
    43801 ttctaattgg ttttatgttc aatataaaga agagacagac cacgctatgt ttttttacaa
    43861 atacttacat aatgtaggag gaaaggttca gcttgatgct atcccaatgc cagattcaga
    43921 ctttacttct gcaatggata ttcttgagcg tacgttagct catgaaaaaa aggttacagc
    43981 tttaataaac aacttagcag ctgtagcaaa ctctgaatca gactttagaa cttctcaatt
    44041 cttactttgg tttatatctg aacaagcaga agaagaaaca aattgtgaag acaatataaa
    44101 acgtgttaaa cttgctggag agggtgggct attctttgtt gaccaagaat ttgctaatcg
    44161 tacatatgca gctccaacaa acccacctgt gacaatataa cgtttaaaaa tttttaatat
    44221 aataaagaag gtgttttaat gaaaatcaag attgattctt atcattaaaa caccttttat
    44281 tattcgtttt atacgtagta ttttattgtt tatacagtgc tatttcacaa tgaaacttaa
    44341 aactatactt tcattttaaa atatttttaa attaaatttg gggtgactga aaatcacact
    44401 atctaactta caaaatgtga ttttcagttg gtgctttaat tatggttgaa taccaaaact
    44461 tataaactat ttatatttaa ctattaaggc atctactgca catacgcctt ttcctttagg
    44521 atatacaaac actggattta agtctatttc cttgacttca tccttatttt cataagcata
    44581 ttttcctaac ttgaccatca tatctgcaag agcatcaata tcacatggct cacttcctct
    44641 atagccattt aaaagcttaa atgattttag ttttttaagc atcataatag cttcatcatg
    44701 atttataggt aatggatata atgtagtatc tttaaatacc tctacaaata ctcctcctaa
    44761 accgactaat aacattggtc caaattggtc atcattagtt ataccaataa taatttctat
    44821 accactttct accatttctt gaactaatat accatcaata ttagcatctg gttttgcttt
    44881 ttttacatta gttaaaatct cattatatgc atctactgcc tcatctctat tcttaattcc
    44941 tattttaact cctccaacat cagatttgtg caatatttca gaagaattta tttttaaaac
    45001 aacaggatac ttaatatatt ttaagatttc atctaattca tcaatacttt ttgcattacc
    45061 ttgtcctgga actggtactc catatttttt catctcaatc ttactatcta attctgataa
    45121 tgctactaca ttatttgact ctcttttctt aacagcttta aattctaaag ttctttttga
    45181 ataatcataa tctataaact tagccatttt attaaaacaa gtaaatgtag ttccaactga
    45241 tgacattata ggcacttgat tatcttctaa tctagtccta taatctaaat atctatttcc
    45301 ttcaagtgta ggaactgcaa acacaggttt tttcaatcct tgttctctag cttcacttac
    45361 agctttacaa agggtttcat gcatttcatt ttcttcatct cttatatttg cacctaccat
    45421 agtaaatcca acactatcat ccttttcaaa ggtatgtaat aaacctacta tcatatcctt
    45481 ttcatggaat aatgctgttg tagcatctag tggattttta ggtgttgcaa atcctggaag
    45541 atatttttcc atttcttctt tagtttcaga agatatttct gcaagttcta caccattttc
    45601 ttctgctaaa tctgcacaaa tagtattttc tcctcctgag aagtttattg ctgcaaaatt
    45661 agaatttgca ggtaaattac catctaaaac actaaaagct tgtgctaaac acataaactg
    45721 ttctaaattt tccacagaaa ttactccata tttttcaaaa atactttcaa aagctttact
    45781 cgaaccagct aaatttcctg tatgagaagc agcagaaata gcaccttttt ctgaccttcc
    45841 tgatttcaat attattactg gctttctttt ttgtgctgcc ctttttaaag catctataaa
    45901 tttttgagga ttttttaaac cttcaaggta aattgctatt actgatgcat aatcatcatc
    45961 tacaaggaaa tctactgcat cttctagtgt aactatattt ccatttcctg ttgaaaaacc
    46021 ataagatata ttaaaataat cacttgaaac aatttcagca gttataaatc cactttgacc
    46081 tacaattcct ataccaggtt ttttagtatc taaatcccat ttagaacctc ctgcccatag
    46141 attaacctta tctatacaat ttagcaaccc catgcagttt ggacccaata ttttcatatc
    46201 gtatgtattt gatatttcta taagttgatt ttctaaatct gtaccttcct ctgtaccttc
    46261 ctctgcaaat ccactagcat ataccactgc tgcctttgtt cctaactctc cagaatcttt
    46321 taatacagat ggaactacat ttctaggcgt acatactact acacagtcta ctacttctgg
    46381 aacttcttgt atcgtcttat aacattttct cccaaacaat tcttctcttt tgggattaac
    46441 ataatatact ctatctgttt ccttactttt tactatacta agtgctgcac ttcttccaaa
    46501 accaagttta tcagtcactc ctactatagc aatacttttt ggtctaataa gtttttccaa
    46561 actcataaat tcacgctcct atatgtttat agttgtgatt ttaagtgaat tttatctcaa
    46621 gatgaagttt ctcttggcac taaagattat taaatcttga gataaatcac ttaagataag
    46681 ggtaatttat caaatggcgt tattatagcc ttccatgaat gctgcttcat tttgaacatt
    46741 aaactttcct tttccttttt cctcaaagaa atcacacata gtttttaaag ctaattcttt
    46801 ttcaaataac ccagttttag caattaatgc tccaagtact actatatttg ctgcttttgg
    46861 attgtttact ttttgagcta attcctgaca atttatttta actacactta tatcttctct
    46921 taatgttaca ttctcatcta ttgcagatgt attaataact actgttccac cttctttaac
    46981 taaatttata taatctaaag atggtttatt cattgctact aaaacatcta tttcttccat
    47041 atcaggccca cctatactct catcagaaaa ctttactaca ctataggctt ttccacctct
    47101 catagttgga ccatatgcag gcatccaagt tacttgtttc cccaattcaa gtgctgactc
    47161 agctacaatc agaccaagag ttaaaactcc ttgaccacca aaccctgcaa atactagctc
    47221 tttttccata actattcacc atccctttgc ttaaattcgc caagagcata atatggcact
    47281 atttcttctt ccatccattt gatagatttc tctagtgata caccccagtt agttgggcaa
    47341 ggtgctaata tttcaactaa ggaatatccc tctccattta attgagcttc tattgcattt
    47401 tttatatatt tttttagatt aattatttcc tttgggctat gaactgaacc tcttgctaca
    47461 tatgctacat caaagaagtt tgccaccatc tcaggaactt tcagtggact accagtagtc
    47521 tttatatctc ttccatttac acttgttgtt gtgacttgac ccggcatagt ggtccatgac
    47581 atttgtccac cagtcattgc aaaattatta ttgtttatta caaatacagt cacattatga
    47641 tttctatatg ctgtatttaa agtttcagaa agacctataa cataagcatc tccatcacct
    47701 tggtaagtca ttactaatgt atctggaagt gctactttaa ctcctatagc tgtagatgaa
    47761 gctctaccat gtgcagtttg catcttatca ccattccagc taaaattcat attgcagaca
    47821 caaccaactc ctaatgttaa tacatgattt ttttcatatc catgttcttc tattacctct
    47881 gctattatac gatttactat tccatgacca caacctgggc aaaacttgtt tggtattgaa
    47941 acaacgctag gtgttaattt ttctgtagcc atattagaac acctccttga tttcgccaga
    48001 ttttattttg ctataagtgt ccattacttg caatgttttt ggtatatgat ttccactaaa
    48061 taaaccatac acaggtacat tttctttaca tactttcttt gaggctaaag caacatcttc
    48121 tactaattga cctgtgtctg ttgattctac tgagataaat ccttttacat ctttacttac
    48181 cttttcaaat gctttatatg ggaaaggcca tactgttatt ggtcttatta ttccaacttt
    48241 ttcaccttgt tctctaagtc ttctaacagc attcatagtt gttcttgatg gtataccaaa
    48301 cgctacaaac acatattctg catcttctac ttgataatct tcccattgtt gttcattttc
    48361 agttattctc atacgtttct ccatacaaaa agttggcttt tggttatctg caacctttgc
    48421 atggtctcta ttacttccat cataagtcca acctaaatct ccttctctct tcttaaactc
    48481 tggaaattct actggttcca tcatttgacc taaagctgct tctgtcaaaa tttcgacagg
    48541 cactctgtac ttctccgcta catcaaatga gttatacatc aaatctacag tctcttgaat
    48601 actgtttggt gcataaacta tcaaatgata atctccattt cctccccctc tagtatctct
    48661 tagatagtct gtctgtgctg agtccaatga gccaagacca ggcccccatc tctgtacatt
    48721 tacgattaca caagggtaat gatttgcaca taagtaagaa atcccttctt gttttaaaga
    48781 tattcctggt cctgaagaac tcgtcataga cctcattcca cttgcatatg ctccatatac
    48841 catatatata gcagccatct cattttcgga ctgtataaaa gttcttccaa gttcagacat
    48901 tctatgtgat aaaaattcca ttacctctgt ttgtggtgta attggatatc ctgcataaaa
    48961 ttcacaacct cctcttaggg ctgcttctgc aatggcgtgg ttccccttcc acatcttttt
    49021 catattatcc caactccttc taagcctctt gacatgcttc ttctttaatt atttcaaaaa
    49081 cattatctgg acacacctga tagcaaattc cacaaagtat gcatttactc tcatcaactt
    49141 ctacatgagc ataaccttct ttatttatct tacttgatat ttttaatgct ccttttttac
    49201 aagatataac gcagtattca caacttttac atctctctgc gtttattttt aagttcatat
    49261 ctacaccccg tttcataata tttctatcta ttatccaata cttggctctc ctttaatatt
    49321 taatatttcc tttaaaactg ctacaaattt cctattttct tccatagttc caatacttac
    49381 acgtgcatgt gtagcacttg gtcttattac aaaccctctt tttttcaagt cttcaaataa
    49441 cttaggtata tctgttttca tatctacata aaggaaattt gattgtgaat ctacaacatc
    49501 aaatcccatt tttgtaaact cttctttaaa gtaagccatt ccaactctat ttaattcata
    49561 tgtttctttt ataaactctt catcatcaag tgctgctgtt gctccactta tagcaacacg
    49621 atttgcagag aaaggctctt ttactgtaaa taaagttctt attatctcat ctttagcaat
    49681 accatatcct actctaagcc ctgcaagacc atatatttta gagaaagttc ttgttactat
    49741 aacgttataa ttttccctta catacttaag tccatccaca taattaggaa ctgttaaaaa
    49801 ttctatatat gcttcatcca atatagttat aatattttca gggactttct ttaaaaattc
    49861 ttctaactct ttatcatcca caattgttcc tgttggatta ttagggttac atacacatat
    49921 taattttgtt ttatctgtaa tcttatctaa tataccttgt aaatcatact tataatcttc
    49981 tgttaaaggt acttctactg gtatcccttc attttttata gttgcagttc tatatgatgg
    50041 aaatgttggg ttacaatata taacttcatc tcctctattt ataaaagcct cacctattag
    50101 agtgataacg ttatctgcac cattagcaac aataaaattt tctggtttta aatctagctt
    50161 ttcagctaat tttcttctaa gttcgttagc ttctggctct ggataaagtt gaccttgttt
    50221 taacatttca atcatagctt ctattgcttt tggtgatggt cctagaggat tttcatttga
    50281 agctaatttt attatttctt ttacaccata tttttcctta actttttcta ttggttcacc
    50341 tggaacatat tgatgtaatt cttttacggt atttctcaat aatttttcta tcatttttaa
    50401 aagccccctc tgtatatgta ttttcattta tataaacgct attgcgtcta cttactttaa
    50461 tagcttaaat taaccatcta ctcaactttc ttttaactaa gcatttcttt gatttaactc
    50521 ttctcttatt tggtttaatt tcttgtcact tactggatat agtattgcta taacaacagc
    50581 tattattaaa ggtattgcca tagaataaga aatcatattt ataaaacctg atttaactgc
    50641 ttctgtgact accatatcag cttgatatcc cattgagttc attaaaactg ttcttatagt
    50701 agttgcaagt aatactccta cttgtattgc aactggatat agtgacatac ttaagccagg
    50761 taagtctttt cctgatttcc aatgcccata atcacaagaa ccggcaaaga aattaagatt
    50821 tattattgat actacatttg aaaaacctcc accaattgcc aacaacatag ttactcctaa
    50881 agtagttttc ccccaaggag tccatgcaac caataagtgg catagtgcac atatagaaaa
    50941 agaaattatt gaagctagtt tttgctctct acagattttt ataaacactg gtgcgaaaaa
    51001 catgaatgct acacttacca aaggcatgat tgataaaaat actgctaatc cacgttcatc
    51061 ttctattaca tatttaaaat aatatggagc caaaggtcct aatcctatag atcttataca
    51121 tataagaaat tctaaacaaa atgccatcat aagtggtaca ttagtgaata aagcttttgc
    51181 catttcactt gctttaatct ttggcttctc ttctttttga agaacttctt cttctgctcc
    51241 agattttatt atctctgttg aagaaaacca aaatactaaa aggcatcctg ctgcaaagaa
    51301 taagtaggta cctaaataac ccattccttc tccacctaat acatctgcaa ataaaactaa
    51361 taataacgga tatgaaaaac ctactaagaa tttactaact tctttaaata tattcgtagt
    51421 agttgagcct ataactcggt ctctaggtgt cttagcaact acagggtaaa tagcataaat
    51481 tatagtgaaa actacttgct gagcacaaga tgctattaat aataaagctg tcatcaaagg
    51541 taaaagtaat gctggactta ttttcattaa tggaactatg aaaaatattc catatgttaa
    51601 tgctaacgct gctggtgcat atctaagcca tggataatac tttccttttt tgaatggttg
    51661 tttgtcaaat actgtacctg ttataggagc tacagcaatt tttatgaaag attgtataat
    51721 ttgcatacca cctgccataa ttacaccaag ttttgccaca tcagttaaaa aaatatttgt
    51781 aacagttgat acaaagtaac ctataaaatt gtacgctaaa tttatagaac ttgaatatgt
    51841 gtatattgct cttttcttag ggtctctcat atcatctcta aaatttgata taagatttcc
    51901 ttttggtttg ctttcttgac tactcacatc tacccctccc ttataaaatt tacttacttt
    51961 ttattattca cgtataataa tatatatttt gaatcttaaa tatctcattc ttgattcagg
    52021 agtatatttt tatatgtgta taattttaat ttaattatat tctcaaaatt cataattgtc
    52081 aaacactttt taagttttat tttttactac taaaattaac taaaaagcta tttagactta
    52141 atttaggttt gttttttatt attttcttgt tttgaaatgt cattgaaatg cgtattttaa
    52201 attattttat catatttcta gtgattttaa ttttttataa ttttattcaa gaataattta
    52261 ttcaagatat ttctatacta catccagata ttaaaaatat ctttttctta tttaaattcc
    52321 ttttattttt atacatgtac tattgattta aaaataaaag cgtgttacaa ttacaaaaaa
    52381 gaatctatga gataaatatc aatatgcaaa aatttcagaa ttttcaattt tctattttta
    52441 cgtaatttcc atctaatatc ataaattatt atagctatat taatctaaaa ccaataaaac
    52501 aaatatcgta ctacttttat ataaaatata ttttaaatat attttgtata ttttattaaa
    52561 atattttata aaggagaaaa gactatgtta cttttaattg ttacgtgtgc aatatacata
    52621 tggattggtt tttatttttc aaaaaaagtt aaaacagcat ccgatttcct aatcgcaggt
    52681 agaaatctgc ctttgcctat actagctgca accattgctg ctacatcttt tggaggaggg
    52741 tgcttagttg gtggagttca atggggagct gaaagaggac tttgggttgg aatgtattct
    52801 actataggtg cagctttagc ttgctttata aatgcatttt tcgcaggaaa attaagaagc
    52861 ttatcttgtg atataacacc tgctgattat attgaaacta gatatggtca tagtgtattt
    52921 ttaagagctt atcaaagtct tgtaacacca atatctatac tagctattat gggtagtcaa
    52981 ttgatttctt ttggttctgt atctactgca tttggtattc cttatgatat agctgtaatt
    53041 ataggagtta tagttatcat tatatatact tatacatcag gaatgtgggg agttgcagta
    53101 tcagcattta ttcaacttgc tatttgtata gtgtttttgc caatagtagc ttatataagc
    53161 ttaaaattag ttggcgacaa ccctttactt atgttacaat caatggtaaa agaaccattc
    53221 tttccaggaa ataaatcgat tagtgatttt atgtatacag ttttaccatt agttttaggc
    53281 tcaatatttt cttatgaaag ttttttaaga tatcaatgtg ctgataatgc taaaaatgca
    53341 gttaaaagta gtgtaattgc aggatttata ctattatttc ttgctttccc tataggaata
    53401 attggagcta ttggtggtag tttatttcca aatatatcat ctgttcaggt tttacctcaa
    53461 atgatatcga ctactttgcc acctttaata tctgtattat tcttagctgc tatattggct
    53521 gccataatgt ctactgccga ttcattaatg acctcaatga gtgctattat atcaagagat
    53581 atttataaca aattattaca tcctaatata gaatttaatg atttaaaaaa tactctaaag
    53641 tattctcaaa ttgcatcagc tttgacagct ataataggtg caatcatagc acttaaattt
    53701 gatagtttat tagaattatt gttttggcca gctccattat gtacaggtgt aatatttgca
    53761 ccatttgtaa ttggtctttg ctggaaaggt gctacaaaaa aaggagctat ctatgctgtt
    53821 atagtaagtg ttatattggc attattaaat atgattggta ttcttactgt atttgacaga
    53881 attttggttc ctataatagg tggttctatt acaatattta tagttagcaa attttcaaaa
    53941 aaagattgaa aagagaggta tacacagtaa atatgtcaaa atcagaaaag ggcaaagaaa
    54001 caaaagctag tattataagt gctgctagag aattattttt tgagcaaggt tatcataaga
    54061 caacaactag gcaaattgca gaaagagcta atataaattt aggtctaata agctattact
    54121 tctcaagtaa aagcgaaata ggagctataa tatatgaaga tataagaaat gaaatgcagt
    54181 ctttaatcta taactaccat gaagaaggta ctatgatgat gttctttctt gctatgaatg
    54241 ctgacctttg tttccttcta aaaaacgaag catatagaaa tttttatttg gatatagctt
    54301 atgaagaagc tattttaagc tatcaaagaa gtgtaaccga aatggtcatg aaaagatatg
    54361 ttaatgataa agaatctata gaacatgatg aattaatact ttcttgtatt ggtatacttg
    54421 ctatgaaacc tgaaataatt agagtttata cttcacacaa gtacgatata tcttctcaag
    54481 ctgtaataaa gcattttaca aaacagtttc ttattaatct tggtcatagt acggatttat
    54541 gcgaagagat tttagaggaa ttgagtaaat actatataga tatagttgac aattttactc
    54601 caataataac tcgtgtaaga acttaataaa attttattaa attcttagag actgaaattt
    54661 taaaatcata atttgatttt aggatttcag tctttatcat atttaaagat attttatagt
    54721 atacctgtta ataccataag tgtactatcc aattatatct ataaatttct ttatccataa
    54781 attccaaaga cgccattcat gcccccctac acactcttca tattcaacat ctacacccag
    54841 agaatctgca tattttttaa acatctgatt atttttatat aaaaaatctc tatcaccaca
    54901 aaattgataa attttaggaa tatcttcatt tctttcttta aggttcttaa gtatgtaaag
    54961 taaatcattc tcactatttc tagcgtcttc tggtctacca aaatcgtgaa atagaatgtc
    55021 tgcattggtt tctatttgtt gattttctaa ctcatgaatc atatcaggcg aaccagaaaa
    55081 acttgcaact gccgaaaact cttttggttt tgaaagcgct aattttaaag ctccatatcc
    55141 ccccatagac ataccagcta caaagttatc ttccctttta tctgataaag gaaatatagc
    55201 tctaacaaat ttaggtaatt cctcgcttac aaaagtaaaa tattggtgtc catacgccat
    55261 atcagtataa aaactagttt ctactcttgg tattactagg gctatatttt tatttttagc
    55321 ataatgctct acattagtat atctaatcca tgagctttgg tcatcttcta aaccatgaaa
    55381 taagtataat gttttaaatt taccttcaaa atcatatatc tctttaccac taaaaagttc
    55441 ttttccattt gctacaggca aaattacaat tatatcagtt tctcctccag tatatttaga
    55501 tttaaattta cattctataa atgccacaaa aaacacctct tctataataa ttttatatct
    55561 aaaaagcacc aagagtttaa ctttctcagt gctttaaata ttgcttaatt tatatatttt
    55621 taattataca taatattttt tagctacata taatcggaag tatctgtcgg taatcccttt
    55681 ttgtccaatt tactttcaac aatatcctta attatagaat aaattactgc aaacattgga
    55741 actcctataa ccattccaat aaaacctaat aattttcctg caaccaataa ggagaacaaa
    55801 atccaaaatg cagatatacc aattgaatct ccaagtattt taggtcctat aatatttcca
    55861 tctatctgtt gtattattaa tataatcaac aataaccaga aagcttttat aggagataca
    55921 aacatcacta ttagcgtaga tggtatagct ccaaataaag gtccaaagaa agggataata
    55981 tttgtaatac caattataac tgatattaat aatgtatatg gcattttaac taacgtaagt
    56041 attacaaatg ttagaatacc tataatgaat gaatctaata ttttgccacc taaaaatctt
    56101 ccaaatgtat agttacttct atgagttaat tctaaaattc tggcagcttg tttttctgta
    56161 aatactgcat aagttatttt tttgcttaat ccatagaatt tttctttatc aattaataag
    56221 tacactgaaa caattaatcc tagtacaata ttccatatac tagaggctac attctttaac
    56281 atacttccta atattgggat taaatctgtt acaaacttta taatatatgt aacaaattca
    56341 ttccacttat caactgccaa attaaagtat tgctcatcaa gatttaaatc agtcattaat
    56401 ttatcaataa gcttagttgc attgtttaca tacataggta tatcatttgc tagtccaaca
    56461 atactctcaa ttacttgtgg caatacgaaa tgcataaata agtaaagtat caatgtagct
    56521 gttgcatatg ttaataaaag acccaagcct ctttttgaac tttgttttag tttttttaat
    56581 ttctcacttt ttataaaaat tctgtcttca taaaacttta aaataaaatt aagaagatat
    56641 gcaatagcaa atcctattat aaaaggttgt aatgttgtaa atatagcatc taaattatta
    56701 gaaaatacat caatttgtga tgatactaga taaaatataa tactactagc agctattata
    56761 aatgtataaa ttgctattgt tgtgtatttt gtattccaat taattttcat tttttcctcc
    56821 ttatttctat ataattaaat tttatcacaa aatcaccact tttataacaa atataccaaa
    56881 ttaaaaataa aatatattca gaatacaaat actcaatttt atttatattt attattctac
    56941 aatataacct acattatctt tttaagaacc ttaattaatt tattatcgta tggagcatat
    57001 ctaataggga catccaaatt taattttttt aacacactct tatagtgagt aaatgtatcg
    57061 aatccagctt ttccatgata tgagcccata ccactttcac caataccacc aaaaggtaag
    57121 taattcgtag ctatatgagt aactgtatca ttgatacaac atccgcctgc tggaatcatt
    57181 tctaaaagtt tattttctag gtacttattt tttgtaaaaa tataaagtgc caatggattt
    57241 ggcatttgta taattttttg tattacttca tctaaatctt tatatgttaa aatgggaaat
    57301 ataggcccaa atatttcttc cttcattata ttatcatccc aattaacatt gtctactata
    57361 gttggctcta tctttaatgt ctccttatta taatttccac catagactat cttatcttta
    57421 tcaataagag ataatatccg attaaaatgt ctctgattta tgattttagg aaattgctca
    57481 ttattacatg cattatcccc aaaatactta ttagtataat attttatttt ctctattaac
    57541 tcattttttc tatcttcatg cactaaaaca taatctggag ccacgcaggt ttgtcctgca
    57601 tttattagtt ttccccaagt aagtcttttg gcagtaaggt ctatattagc atcttttaaa
    57661 atgatacaag gactttttcc tccaagttct aaagtaatag gagttaaatg ctctgatgct
    57721 gatttcatga ttattttacc aacattagta cttcctgtaa aaaatatata atcaaatctt
    57781 tccaatagta acttttcact ttcttcttga cttccttgaa caactgcaac atattctttt
    57841 gaaaaagtat cttcaactat gtctttaact acactagatg ttgacacaga atattcagaa
    57901 ggttttaata taacacaatt ccctgctgct aatgaccaaa ctaatggtat aagtgctaat
    57961 tgaaatggat aattccaagg tgacattatg agagtaacac cataaggttg tggaacaact
    58021 ttggatatag atggaaaatt aaccatactt gatttaactc tttttatttt gctccatttt
    58081 cttatattct ttatagcaaa gtttaattca ctataaaaca tgcctacctc tgtcataaaa
    58141 ccttcaaaat ccgatttatt taaatctttc tttagtgcta aaagtatttt ttcttcattt
    58201 tgtgatacaa ctaacttaag tttcttcaac tgttctatac gaaacgatat atctcttgtt
    58261 ttacctgtat tataatattt tctttgcatt ttaactaact cttttatatc cattgttaaa
    58321 aatcctttct ttaagaatta tactaataca tttttagaaa aagatttaaa tttatcctaa
    58381 cattattttt tatatcataa taaattcatc tcaatataac ataaatcttc caataaaaaa
    58441 agccccttat taagtataag taagcttata aaatagttta ttttaaaata aacatttttt
    58501 aaaattataa ccttattgaa acaattaaat tatccatctt taataatatt attttataaa
    58561 taatgtctag taagtttcta tgaaatctaa ctttagataa taaataatta caaatatata
    58621 cctcttaaag ttctcttata taatcaagta ttggagttaa attttcttta ttacaccaat
    58681 caaaggcttc tccagacaat aaaggtgctt ctgctggttt aagaccttga cgttcttttt
    58741 tagctataga ttttttaaaa aaactacaaa gagtataatc tataaaagac atttttgtct
    58801 catcccatgc cccacgacaa taaaagcaag gaattttgtt taattcatcc ttaaaattta
    58861 cttctcttaa tttctttatt acttcatcat catatggagc agctcctacg ccaaatacta
    58921 ctaaattttt tttctgcaat tctttataat ttttttttaa gaaagaaatt cccgctatat
    58981 tacaagcata aagacctcct cctaaaataa tcgtatcata cttcataacc ttttctatat
    59041 taatattctt agtttcaaaa atatcacaag acaataattc tgaaagccat ttagcatatt
    59101 tttttgttga accatactta ctcttataaa tcactactac atttttcata taaattatcc
    59161 ccctctctga tgtcatacaa agttgatttg atacttgctt attctccaac gtcattattt
    59221 tctacataat ttttcacatt ttcaattcct atacttaatt tcataattcc aaaaaataac
    59281 tgttccactt ctttctctgt aaaatcttca aataaaagct gtaatacttt ttcctgcata
    59341 cctcttactt ttttagaata ctcttgcact ctatcttttg tcacaagaca gatagctctt
    59401 gaatcttttt cattctgctc aatttgtata aaacctttct tttctaaagc aatagctagt
    59461 ttttttacat tttgtcttga gcaccccatt aattctccaa gtttggttaa tgtaagagtt
    59521 tcatctacag agtccgcaat agctaaaagt aaccattgtt tcattgttaa ttctgggtct
    59581 aatttatcac atgtagtttg aagtttattt tgcattacaa atatacttgc aaatatagct
    59641 tgttttctac tatcatcatc taccatatat tttttcatta aactttctgc atccattatt
    59701 atacacttct ctttatctta gattttaatt ttttgataat tttaaatagt aactaattac
    59761 tttatattat agtaattagt tactattatg tcaataaatt tatttttatt ataaacggca
    59821 aaacggcata gcattatggc tataccgttt cataaaatca tatttacaat caatttataa
    59881 taaattataa attaaatata ttttaggcta taataagttt ttcaaaattt actctaaagc
    59941 atacttttta tacttattat attctatatt gctacattct acatctaaaa tagctccatc
    60001 ttctctgtat tctgtattta taatgctcgt attttcgtta aaataagaaa ctacatgacc
    60061 tttatcatat ggaattaaga acttacatct tacataatct ttaaatatgc tatcacaaat
    60121 acattttatc attttatcta tatttatatc ttttttaact gaaacaaata taccttcttt
    60181 atcgatacta tctaaaattc tatccaatac ttctacatct attaaatcaa ttttattata
    60241 cacatgtatc ataggtatac catctgcacc tatttgtttt aaagtatctt ctgtcacttt
    60301 aatatgactt ttatagcttg gatttgaaat atcaataaca tgtaacagta cgtctgcctc
    60361 acatgcttct tctaatgttg acctaaatgc ttttactaag tcatgtggta gattacttac
    60421 aaaaccaaca gtatcagata ataaaaattc tttgttattt gcaagaacta tatttctgac
    60481 agaagtttca agtgtagcaa ataacatgtt tttctcaaac actttctttt cttcagagtt
    60541 tttaaatata tctactagtt tattcattat tgaagattta ccagcatttg tatacccgac
    60601 tagagctaca tttggaagat ttgattttct tctcatactt ctttgagttt ctctttggaa
    60661 ttttaaatca tccaactccc tatttaaaga tgttatcttt tcttctattc ttctacggtc
    60721 aagttctaat tttttctcac cagaacctct atttttagta ccaactccac cactttgacg
    60781 tcctaaattt tcatttgaac ctataagtct tggtaacata tattttaaac ttgctacttc
    60841 tacttgaagt ttagcttctc tagtttttgc cctttgtgca aatatatcaa gtatcaatgc
    60901 cgttctatct ataatttcac aattaagctt ttcttcaaga ttttttagtt gtgatgtaga
    60961 aagttcattg taaaatataa ctatctctat attttctttc tttattaagt ttaatatttc
    61021 ctcaacttta cctgtcccaa tgtaaaatgc tctattaacc tgctttgcat tttgagttat
    61081 actccctaca acatcaatat cacatgctga acataagttt tcaagttcaa tcattagttc
    61141 attaaagtcc tcagatttat tatttatgtt taatcctact gttattcctt ttttcgccat
    61201 atccatattc tccttatctg ctatttttta tttaatctat agcacgagat tatggctcta
    61261 taattaaatt catcaagaat tttgcttttt atcttatcct taaatgacac ttcttattta
    61321 ctattataat aaccataatc gtgcattatt ttctcaatct tatataaaaa atcactttct
    61381 tacacctcct cccaaatata ttatgcagtt ttttcaataa aaaaactcct tacaaatcta
    61441 agtaatacaa aacaagctac ttatatcata agaaggatta aaattctaaa tatatattaa
    61501 aaatacatta gtttaattaa cttatatgta attatcattt tatatttaac cctattctta
    61561 aatttaagta gttatttgca tgattaataa aagtaataaa aacatatact tcaatataat
    61621 catcaactat taaaattaaa ttctatttat aataaaattt aaagaataaa attaaatata
    61681 cattttgata atcacctcca acattttcct tactacatat tataataaaa taaacacttt
    61741 gtaaagacat aaaattatgt ggctatctca aaatatagag aatcctcttt ttcattgtta
    61801 aaatgataaa aatacacttt atttcataca caaaagagtg ccttatgaat taaaaagttc
    61861 attttaaggc accctcattt attttatctt attaattaca tgtctatgct aagatagttt
    61921 tttgttacat tgcttcatct tcttcaaatt gagaattgta aagattggca tagaatccgc
    61981 ctttctttag aagttcctcg tgatttcctt gttcaactat atctccttca ttcattacaa
    62041 gaatcatatc agcatcacgt atagttgata atctgtgggc tataacaaaa cttgttctac
    62101 cttccataag attatccata gctttttgaa tcaatacttc tgttctagta tcgacagaac
    62161 ttgtagcttc atctaatatt aaaattttag gatcagctaa aatagcacga gctatagtca
    62221 ataattgttt ttgaccttga gaaacattac ttgcttcttc atttaatttc atcttatatc
    62281 catctggtaa tgtcttaata aatctatgaa catgtgcaga tttagcagcc tctataactt
    62341 cttcatctgt agcattcaac ttaccatatc ttatattttc cataattgaa ccactaaata
    62401 accatgtatc ttgaagaacc ataccaaaca tttctctaag ctcactacga ttaaaatctt
    62461 taatattatg accatcaatc agtattgaac cgctattaac atcataaaat ctcattaaca
    62521 gtttaactat tgtagtttta cctgctcctg taggtccaac aatagcaact ttttgaccag
    62581 gtttaacatt tactgagaaa tcatttatta tagtcttgtt tgggttatat ccaaagttga
    62641 cattttcaaa atcaatttta ccttctaaac catctattga aactgcattt tcaacaattt
    62701 ggacttcttc ttcctcttct aaaaactcaa atactctttc agaagctgct gctgttgatt
    62761 gcaataaatt ggcaacctgt gcaatctgag tcattggctg tgtaaagttt cttacatatt
    62821 gtataaatga ctgtatgtca ccaacctcaa ttgttttctt aattgcaagc caacctccta
    62881 agattgatac cattacatat cccaagtttc caataaacat cataagtggt tgcattatac
    62941 ctgataaaaa ttgagatttc cacgctgaat tatacaggct atcatttagt ttatcaaact
    63001 cttcaattac ttcatcctca cgattaaatg cttttactat tgtttggcca ctgtaagttt
    63061 cctcaacttg accatttaca tttcctaaat attcttgttg atatctaaag tatttttgtg
    63121 atttctttat tattcttgaa attacaaaca ttgatattgg taatattaaa actgccacta
    63181 atgtcataat tccacttata gataacatca ttatcaaaac acctatcata gttgttactg
    63241 atgttataag ctgtgtcata ctttgattta aactttgatt taaagtatct atatcattcg
    63301 taattctcga taatatttca ccatgcgtct tagtatcaaa atacttcatt ggcaatctat
    63361 ccaattttgc tgaaatctct tttcttaaat tataggatac tttttgagaa attccactca
    63421 ttataaatcc ttgtataaaa gagaacagtg cacttatcaa ataaaggaaa agtaaaaagg
    63481 ttaagatttt tccaattgca ttaaaatcta tacctacgtt tcctccagaa actttactca
    63541 ctagcccttc aaatatcttt gtagttgcct ttcctaaaat ttttggacct actatagaaa
    63601 acgacgcact accaatagca aatacaatta ctagaattat tgatatttta aatttagata
    63661 aatatgcaat tagttttcgc atagtccctt taaagtcatt tgctttttgt cctgctccca
    63721 tagattttcc cataggacct cttcccattc tactcattag ctagctcctc ctttgaaagt
    63781 tgtgataaag ctatttgctc ataaacttcg caatttttta gaagctcttt atgtgttcct
    63841 attccaacta tttcgccctc atttaaaaca attatctgtt ctgcatttaa gatagtacta
    63901 attctttgtg caactattag aactgtactt tcagcagttt ttgattttaa agccttacga
    63961 agagctgcat cagtttttaa gtcaagtgct gaaaaactat catcaaatat ataaacttct
    64021 ggattttttg ctattgctct tgcaatagaa agtctttgtt tttgacctcc agatacattt
    64081 gttccacctt gagaaatttc agttttaaaa gcttccggtt tagaatctat aaattctgta
    64141 gcttgagcta tttcagctgc tgttctcatt tcttcatctg ttgcgtcttt tctaccatat
    64201 tttaagttgg attctatagt accagaaaac aatactccct tttgaggtac atatccaatt
    64261 ttttccctta aatcatgttg agaaacattt tttatattaa ctccaccaag taatatttct
    64321 ccttcagtaa catcaaagaa acgaggaatt aaatttataa gagttgactt accactacca
    64381 gtacttccta taaaggcagt tgtttctcct ggctttgctg taaaagatat atttgttaat
    64441 ataggttctt ctgcgtctgg atacatgaac gaaacatttt taaattcaac aagacccttt
    64501 ttatcttcct taaactcttg tgcctctgat ttttctgggt cttttatgct tatatctgac
    64561 actaatactt catctatacg tgtagctgaa acggatgctc ttggaagcat aatagatacc
    64621 attgatatca ttaagaatga cattattatt tgcattgtat attgtataaa tgccatcata
    64681 tctccaactt gcattgctcc agaatcaaca ctgtatgcac ctctccaaac tataagaact
    64741 gtgataaggt tcattataag catcatagca ggcatcatac atgtcataac tctatttaca
    64801 aaaagatttg ttttagttaa atttttattt gctttatcaa atctttcttc ttcatgtttt
    64861 tcagtactaa aagctctgat aactggaata ccagtaatta tttcacggct tactaagttt
    64921 aacttatcaa caagcttttg aaccagttta aacttaggca taaccactga gaataacact
    64981 acaattaatg ataagatagc aactactgct actgctataa tccaggccat tgaagtattt
    65041 gtgtttaaaa cctttatcac tccacctata gccattatag gtgcatagaa tactattcta
    65101 agcaacataa ccatcaacat ttgtatctgt tgaatatcat ttgtactacg agtaattaat
    65161 gaagctgtag aaaattcatt catttcagta tttgaaaatg acataacttt tctaaatact
    65221 ccacttctta aatttctacc tacacttgcg gctactcttg ctgctaaaaa tcctactgtt
    65281 attgtagcta ccatactaat cattgctata ccaagcattt tagcaccagt aaataatata
    65341 taattatttt gagttttttc tgtatcaata cctattttct catattctga ccttacatat
    65401 gaaacagagc tttgtgttat catactctct ggcatacttt caaagccttt gctcatctct
    65461 ttagtcaatg tatctaactg ttcctttggc attgctgata acaatttaaa tatatcaaca
    65521 tctccacttt gagtagcttg tggtggaagt ttgctcatta actgagcttt catagctttt
    65581 acctctttac tatcgccctc aagccctgat actattaaaa tagctttacc aaaaataaca
    65641 tttaaatcat ctatagtgtc tttgtcttta gtatttaact cataaagaga ttcatctttt
    65701 agacctggat acttatcttt atacttaaca taatcctttt tattcagcaa agtataatta
    65761 tctagtactt tatccttact acttttatcc ataaataaag taattttatt taattcactc
    65821 tctctaatca cagatggaac agagttttct actccacctt gttgtatacc tacatttact
    65881 atattggatg tgtattctgg taaagaaagg tcacataccg cttgaattac caatagacag
    65941 actattatta ctattgataa tgccgatttc tttaaatatt taattaattt aaacatacat
    66001 ttcttccctt ctgtaatatt aattagtcta ataacattaa attgaaaaac attattttaa
    66061 actttaaaaa tatttttcat cttcatgctt atgacatcct gcttttaaat tatctcgtac
    66121 ttgcattaga agtcttctaa gtactatttt ttcttcttca ctaaatccta aaaaaaactc
    66181 tctttccaat tccttgttaa attcttcaac tttattacat atttctaaac ctttgtctgt
    66241 caaaaaaatc ctagatactc tttggtcctt ttcatcttgt tttctttcca caagtccagc
    66301 tttttccatc ctctttatca taactgtagt tgtagatgct tttactttcc ttttatctgc
    66361 taattctttt tgactttgcc catctttcat ctttaaagaa aaaagtattt ggggttgacc
    66421 atgatataag cctaatttat caaaataaaa atgagttctt ataaaatata ttcgcattaa
    66481 ttgcaagaaa acatcattta atttttcttc agaattgcta ttcatacttg ccctccttat
    66541 tttttatatt acttagtcgg ctaagcatta ttttactata ctgcatgcat tttttcaata
    66601 tatttataaa aaattcatat aaatttcatt tattaaatat ttttatatca tatagttata
    66661 attttaataa ataatagtaa gatttttaat tagtcagcta cttatatttt ttattgtaaa
    66721 gcttaaaata aaccttttca tatattttca aataaaaaag ttgtcccaaa ataaattttg
    66781 aaacaacatc atattcaaca gtatcttgat tatataacat tatgatactc tacttatctt
    66841 catatccatt tacaacaacg tctaacttcc cagtttcagg tgatataatt agaccatgta
    66901 caataatacc atctggaatt aaaggatgcc cttttattaa atcaatacta tcttttacag
    66961 attcttctgc agaatcgaat ccatgtaacc attgttttgt atcaattcca gcactacgaa
    67021 gtgtaagtat tacatcatta gatattcctc tatctaaaat tttaccaagt aacttatccg
    67081 tatcaacatt acacatacca catccatgat gccctacaac cataacctca tctacatcaa
    67141 attcgtaaat tgcaactaaa acacttctca taatacttcc aaaaggatgc attatagtag
    67201 ctcctgcatt ttttattagt ttcacatctc catttttcaa attcatagcc ttaggcaaaa
    67261 gctcagttaa tcttgtatcc atacaagata agactactat ttttttattt ggatgttttg
    67321 atgtcacata ttgttcatat tctttgttct ctacaaatga tttattatat tctaatatct
    67381 cttcaagttt tctcatatgt aatatcaccc tctttaaaaa tttttttatt attatatcac
    67441 tattaaagta caatatatac acatataatt taatttatat ttattaaatt attttataag
    67501 attattactc tactataaat cttgtatata acttgtattt ataagtattt gtatatttat
    67561 tttttataat ctaaactaat attatatatt ttcattattt ttttaattat aatt
//
LOCUS       DAYAOO010000010        66452 bp    DNA     linear   BCT 12-OCT-2024
DEFINITION  TPA_asm: Clostridioides difficile isolate ST8-SSI-h139-18
            SAMN40601845-rid21577343.denovo.010, whole genome shotgun sequence.
ACCESSION   DAYAOO010000010 DAYAOO010000000
VERSION     DAYAOO010000010.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN40601845
            Sequence Read Archive: SRR28438827
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 66452)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 66452)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-MAY-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-MAY-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002157583.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002157583.1
            Genome Coverage       :: 163x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/11/2024 16:19:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 4,038
            CDSs (total)                      :: 3,963
            Genes (coding)                    :: 3,930
            CDSs (with protein)               :: 3,930
            Genes (RNA)                       :: 75
            rRNAs                             :: 6, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 60
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 33
            CDSs (without protein)            :: 33
            Pseudo Genes (ambiguous residues) :: 0 of 33
            Pseudo Genes (frameshifted)       :: 7 of 33
            Pseudo Genes (incomplete)         :: 25 of 33
            Pseudo Genes (internal stop)      :: 11 of 33
            Pseudo Genes (multiple problems)  :: 8 of 33
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..66452
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN40601845-rid21577343.denovo.010"
                     /isolate="ST8-SSI-h139-18"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Denmark"
                     /collection_date="2018"
                     /collected_by="Statens Serum Institute"
     gene            480..617
                     /gene="rpmH"
                     /locus_tag="ACGI5H_000717"
     CDS             480..617
                     /gene="rpmH"
                     /locus_tag="ACGI5H_000717"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420485.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0000315 - organellar large ribosomal
                     subunit [Evidence IEA];
                     GO_component: GO:0022625 - cytosolic large ribosomal
                     subunit [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L34"
                     /protein_id="HFG9696446.1"
                     /translation="MSKRTYQPKKRQRSKEHGFRKRMKTSNGRNVLKRRRAKGRNRLT
                     H"
     gene            695..1039
                     /gene="rnpA"
                     /locus_tag="ACGI5H_000718"
     CDS             695..1039
                     /gene="rnpA"
                     /locus_tag="ACGI5H_000718"
                     /EC_number="3.1.26.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420486.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000049 - tRNA binding [Evidence IEA];
                     GO_function: GO:0004526 - ribonuclease P activity
                     [Evidence IEA];
                     GO_process: GO:0008033 - tRNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease P protein component"
                     /protein_id="HFG9696447.1"
                     /translation="MDFNRTKGLKKDSDFRKVYKHGKSFANKYLVIYILKNKSDYSRV
                     GISVSKKVGKAITRNRVRRLIKEAYRLNIDEKIKPGYDIVFIARVSSKDATFKDIDKS
                     IKNLVKRTDISI"
     gene            1071..1322
                     /gene="yidD"
                     /locus_tag="ACGI5H_000719"
     CDS             1071..1322
                     /gene="yidD"
                     /locus_tag="ACGI5H_000719"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892330.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="membrane protein insertion efficiency factor
                     YidD"
                     /protein_id="HFG9696448.1"
                     /translation="MNKIIYILKEISKYLSNLCIYLVRFYQKYISPLKGPTCRFYPTC
                     SQYSIEAFKKYGFVKGMYLTIRRILKCHPFHPGGYDPLK"
     gene            1354..2061
                     /locus_tag="ACGI5H_000720"
     CDS             1354..2061
                     /locus_tag="ACGI5H_000720"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429300.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YidC/Oxa1 family membrane protein insertase"
                     /protein_id="HFG9696449.1"
                     /translation="MNIIGNFLGLILKVIFEFVNHYGISIILFTILVKIILLPLTIKQ
                     TKSTKAMQDIQPRIKEIQEKYKNKPEKQNEEIVKLYGEAKINPLSGCLPLLIQFPILI
                     GLFSVLREPVAHGVFANKAAFLAADNGFLWIKSLTSPDYVLAVFSGASAYVMQKVMTP
                     KDQLQGSMKVMTYVMAGMSFYWGFIFPAGLTLYWTVSNLFSIAQYYLIMNPLKAKLAA
                     NSKEEKVNEKKPKINKK"
     gene            2030..2659
                     /gene="jag"
                     /locus_tag="ACGI5H_000721"
     CDS             2030..2659
                     /gene="jag"
                     /locus_tag="ACGI5H_000721"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434235.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003676 - nucleic acid binding [Evidence
                     IEA];
                     GO_function: GO:0003723 - RNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-binding cell elongation regulator Jag/EloR"
                     /protein_id="HFG9696450.1"
                     /translation="MRKSLKLIKSKSKEEAISKAIAELNLKAEDIEVEILENPSKGFL
                     GFIGAKDGTYEIFVIEREVDVAKNFIEVMLKNANVDAKVNVSQKDNLIMVDIEGKEAA
                     SLIGRRGETLDSIQFLTGLALNKINKDSHTRVLVDIENYRSKREESLIRYANKVAREV
                     AKTRKTKKLDYMNPYERRIIHSALQNDKYVITYSEGTDPYRRLVIECKR"
     gene            2771..4150
                     /gene="mnmE"
                     /locus_tag="ACGI5H_000722"
     CDS             2771..4150
                     /gene="mnmE"
                     /locus_tag="ACGI5H_000722"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898860.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003924 - GTPase activity [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_process: GO:0006400 - tRNA modification [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA uridine-5-carboxymethylaminomethyl(34)
                     synthesis GTPase MnmE"
                     /protein_id="HFG9696451.1"
                     /translation="MFIDDTIAAIATAPGEGGIGILRISGEKALKVAEEIFKSMSGKS
                     IEEYNKRTLIYGNIVDNENIIDEVLLAYMKGPNSYTGEDVIEINCHGGFISVKKILEL
                     ILSKDVRLAEAGEFTKRAFLNGRIDLSQAEAVIDVIKAKTDIAHEVAQNQLEGSLSKK
                     IRELRDKVTEILAHVEVAIDYPEEDIEHITYQTLKEKTDELKKDIKKLYDTAESGKIL
                     REGLKTVIVGKPNVGKSSLLNSILGENRAIVTDIPGTTRDVIEEFVNIKGIPLKIVDT
                     AGIRDTDDIVEKIGVEKSKESFTSADLIVMVLDASRKLSEEDIEILEKLKDKQTIVLL
                     NKNDLKQEIEEEKILKYVENNSIIKISALQQEGIEELQDKIESMVYKGSIKNNSSLVV
                     TNSRHKDALSKAYKSATDALIALEQSMPFDFVEVDLKNIWDYLGYINGDTVTEDLLDN
                     IFHNFCIGK"
     gene            4245..6140
                     /gene="mnmG"
                     /locus_tag="ACGI5H_000723"
     CDS             4245..6140
                     /gene="mnmG"
                     /locus_tag="ACGI5H_000723"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892325.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0002098 - tRNA wobble uridine modification
                     [Evidence IEA];
                     GO_process: GO:0008033 - tRNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA uridine-5-carboxymethylaminomethyl(34)
                     synthesis enzyme MnmG"
                     /protein_id="HFG9696452.1"
                     /translation="MIKFEAGKYDVIVVGAGHAGCEAALATARMGYKTLIITMSLDSI
                     ALMPCNPSIGGTGKGQLVKEIDALGGQMGLNIDKTYIQSRMLNTAKGPAVHSLRAQAD
                     KFKYHEEMKKTLEDEPNLDIAMDEVVEILHEGNVVIGVGTKLGCSFKSKAVILATGVY
                     LNSKIYMGEVAFYEGPNALGYAKYLTDSLVELGLRMRRFKTGTPARVHRDSIDFSVMS
                     LQEGDEKVTPFSFMNENIEKKQEPCYLTRTTEETQKVILDNLKRSAMYSGVIESTGPR
                     YCPSIEDKVVRFSDKTSHQLFIEPEGLNTKEMYIQGISTSLPFEVQLDMYKTIKGLEN
                     CKIMRPAYAIEYDCVDPTQLKISLEIKGVENLFSAGQFNGTSGYEEAAAQGLMAGINA
                     VRKIEGKEPFVLDRSEAYIGVLLDDLVTKGTNEPYRMMTSRAEYRLYLRQDNADMRLT
                     QKGYDIGLVKKDRYERFLNKKAAVEKEFERLKNERVTPKEVNSLLEEKGATPIKVGIS
                     LYEFLKRPEVTYELLEELGKGAGEDVSREVKEQCVIITKYEGYIEKQLKQIDQFKKLE
                     NKKLDEKINYSSIEGLRLEARQKLDDIKPISIGQASRISGVSPADISVLLIYLEQIRR
                     TRGGKGE"
     gene            6133..6852
                     /gene="rsmG"
                     /locus_tag="ACGI5H_000724"
     CDS             6133..6852
                     /gene="rsmG"
                     /locus_tag="ACGI5H_000724"
                     /EC_number="2.1.1.170"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729282.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005575 - cellular_component [Evidence
                     IEA];
                     GO_function: GO:0008168 - methyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0031167 - rRNA methylation [Evidence IEA];
                     GO_process: GO:0046118 - 7-methylguanosine biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (guanine(527)-N(7))-methyltransferase
                     RsmG"
                     /protein_id="HFG9696453.1"
                     /translation="MNNIELLKNGIEGFNIDTNDSMLEKFKIYREILVDWNKKMNLTG
                     IEDEKEVYIKHFLDSISAVKNGYIKNGMSIIDVGTGAGFPGIPLKICLDSLELTLLDS
                     LNKRINFLEEVSRVLELDNITFIHGRAEDFGKDEDYREKYDVATARAVAGLPILMEFC
                     VPFVKVGGYFICLKGPNANLELEESQKAIDVLGLEYIEKIDVELPEVDLNHNILVFKK
                     VMETPVKYPRKAGKPAKNPIK"
     gene            7015..7800
                     /gene="noc"
                     /locus_tag="ACGI5H_000725"
     CDS             7015..7800
                     /gene="noc"
                     /locus_tag="ACGI5H_000725"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429292.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0043565 - sequence-specific DNA binding
                     [Evidence IEA];
                     GO_process: GO:0032466 - negative regulation of
                     cytokinesis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoid occlusion protein"
                     /protein_id="HFG9696454.1"
                     /translation="MEDKRVMEIPIEDVVPNPYQPRKIFSQVSLEELSNSIKVYGIIQ
                     PITVRAKDGKYELIAGERRLRAAKLAELKTIPAIINNMNDESSAVLALLENLQREDLN
                     FIEEAIGYENLIKEHAFTQQQLAEKLGKNQSTVANKLRILKLPNDIKMKLIENNLTER
                     HARAFLKLPSEDLMQSVLDKVIKNELTVKKTEKLIQDVLEETKVQEEPDKKQNIKGAM
                     SIRIYINTIKQAFDAISNTGIDAKYNEIDKGDYMEVVVKIPKK"
     gene            7935..8708
                     /locus_tag="ACGI5H_000726"
     CDS             7935..8708
                     /locus_tag="ACGI5H_000726"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420496.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HFG9696455.1"
                     /translation="MGKVIAVFNQKGGVGKTTTNVNLSASLGTLGKKILVLDLDPQGN
                     TTSGYGINKNEVENTIYEIMLDGLHIKEAIISTEFENVDVVPSATELSGAEIELTSKT
                     NREYILKNSIKAVIDEYDYIFLDCPPSLGMLTINCLTAVDSVLIPIQCEYYALEGVSQ
                     LMETIKLVKSRLNADIEIQGVVLSMFDGRANLSIQVVEEVKKYFKGSVYTTLIPRNVR
                     LAEAPSHGKPVIYYDKRCRGSVAYLELAEEFIDLEEEEW"
     gene            8710..9573
                     /locus_tag="ACGI5H_000727"
     CDS             8710..9573
                     /locus_tag="ACGI5H_000727"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429290.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ParB/RepB/Spo0J family partition protein"
                     /protein_id="HFG9696456.1"
                     /translation="MENKSKRSNRLGRGLSALIPEIKGETSEKEIVNIDIDKIYPNEV
                     QPRKQFDEEKIKVLSDSIKNYGVLQPIVVKMDENNKYMIIAGERRFRASKLANKNQIP
                     AIIKDIDMKDIMEIALIENLQREDLNSIEEALAYKSLIEHYNVTQEEISEAVGKSRPH
                     ITNTLRLLNLGQDVIEMIDSGRITAGHGKALLRIADKDLQLQIAKKIEEEELSVREVE
                     NIAKKISENKQEEPKKSKPKDVFILDVEDKLRNIFGTKVNISKGKKKGKIEIEYYNDD
                     DLNSIVSMLLE"
     gene            9606..10748
                     /locus_tag="ACGI5H_000728"
     CDS             9606..10748
                     /locus_tag="ACGI5H_000728"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892319.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminotransferase class V-fold PLP-dependent
                     enzyme"
                     /protein_id="HFG9696457.1"
                     /translation="MIYLDNAATTYPKPERVYNAVLDCMKNYCANPGRAGHKLAMRAA
                     REIYDTRENIAKLFNVSNPMNIVFTSNATDSLNLAIKGVLQEGDHVITTSMEHNSVIR
                     PIKALEKRGIENTVVKCDYEGFLDYEDLEKSIKSNTKLIVTTHASNVCGTLIDIKKVG
                     EIAKKHNILFLVDASQTAGVYDIDVNECNIDMLAMPGHKCLFGPQGTGILYVREGLNL
                     NILKEGGTGSKSEEIVQPELFPDKYESGTHNTPGIAGLNQGILFIFERGINNIRQHEE
                     ELCQYMIDKLEEVPDIKIYGPKDSKKRASVIALNIGDMDSGEVTFLLDSDYNIATRSG
                     IHCSPLAHTTLGTLKQGAVRFSIGYFNTKDEIDKAVEALKKISKNK"
     gene            complement(10882..11457)
                     /locus_tag="ACGI5H_000729"
     CDS             complement(10882..11457)
                     /locus_tag="ACGI5H_000729"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898849.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GerMN domain-containing protein"
                     /protein_id="HFG9696458.1"
                     /translation="MKNKKIMLVLSILSISIFAVGCTNAQNGSDSSKKETKSNTNVEQ
                     PKEENNTEKEVPNNKAKPTPKEETKTQSATIYSFDVDKTDLIENKVDLNKIDENTLFE
                     ELQKLKVVPESAKLNSFTTKDIDGVKTGILDVSSDFTKSNLGSDAETLMLDSVARTYI
                     KNMNVEQIKITVDGSNYESGHIVLEEGDYLK"
     gene            11717..13009
                     /gene="rstA"
                     /locus_tag="ACGI5H_000730"
     CDS             11717..13009
                     /gene="rstA"
                     /locus_tag="ACGI5H_000730"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894114.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="toxin production/motility transcriptional
                     repressor RstA"
                     /protein_id="HFG9696459.1"
                     /translation="MEILSLGEKIKKLRKEKNMTLKELAGDRITAAQISHIERDKSHT
                     SYELLEYLGDKLDVSVEYLLETKEMQSKKITDNLILQSEIYIKENELNKAEDQIKEVL
                     DICKRYDLMENYGRCNFLMANINLKKSNYNDAIENFEKALYFFIKNSDSENILKCYLN
                     IGKIYMQEDFYKGAISHFNFAEEILSENKFEDVNIHKELYSKMAYCYIKLDNPNMSLK
                     YIEKINEIDNRNDRKEDVDILVLKANNMLEIGKYEESRDYFKKALKILESEDNKTGLA
                     NVYLTICDVYRKIGETDRVLEYSQKVYDIKKNDEDEYMMSGLFKIIEAYIDKEDYDLA
                     RKYCKIALASSIKNKNKFNEYKALRFYANMYKNQNEVTLAIEYLIKCIKIVSDLGNNR
                     ILANLYIDLGQLYSNISKEKELEYYQKGVFMYKNLEIM"
     gene            13114..13716
                     /gene="yedF"
                     /locus_tag="ACGI5H_000731"
     CDS             13114..13716
                     /gene="yedF"
                     /locus_tag="ACGI5H_000731"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009906589.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sulfurtransferase-like selenium metabolism
                     protein YedF"
                     /protein_id="HFG9696460.1"
                     /translation="MSIKIDARGLACPKPVINTKRELDNLEEGVVVTIVDNETAKENI
                     LKLAKSLSCEANIVDEKENFISIEIRKGKNILDKQNVVDNKESELDNTCIFISSDKMG
                     LGNDELGKVLIKGFIYTLTESKPYPKYVLLVNGGVKLSAENEETIENLKILENMGVEV
                     LSCGTCLDYYNLKDKLQVGTVTNMYTIVETLKNASNTISI"
     gene            13789..14052
                     /locus_tag="ACGI5H_000732"
     CDS             13789..14052
                     /locus_tag="ACGI5H_000732"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434250.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3343 domain-containing protein"
                     /protein_id="HFG9696461.1"
                     /translation="MNQMYIVSFNSTHHAIRSEKLFGENSLKVMALPTPREITASCGI
                     SIKFSFEDMEKIKTILVENNVDIKGIYCISKLENGSKEVEKLD"
     gene            14067..14252
                     /locus_tag="ACGI5H_000733"
     CDS             14067..14252
                     /locus_tag="ACGI5H_000733"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898844.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF951 domain-containing protein"
                     /protein_id="HFG9696462.1"
                     /translation="MPMDLKIGDIVELKKQHACGCKEFEIIRTGMDIKIKCTKCSRLI
                     MLDRETLEKRVKKLIKK"
     gene            14355..15551
                     /locus_tag="ACGI5H_000734"
     CDS             14355..15551
                     /locus_tag="ACGI5H_000734"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429271.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PLP-dependent aminotransferase family protein"
                     /protein_id="HFG9696463.1"
                     /translation="MAVKYAKRMQGLQGSEIRELLKLTQQPQIISFAGGMPAPELFPV
                     EEMKKVSVAVLEENGRSAMQYTTTEGYEPLREKIAARMNDKNKTNVNKDDILVTSGSQ
                     QGLDFAGKVFIDEGDVILCESPSYIGAINAFKSYQPKFIDVPTDSDGMIMEELEKILE
                     TTDRIKMIYVIPDFQNPTGRTWPLERRKKFMEIVNKFEIPVIEDNPYGDLRFEGETLP
                     SLKSMDTKGLVIFLGTFSKIFCPGYRLGWTCASPEILSKFNFAKQGADLQASTISQME
                     VSKFMDMYDLDAHVDKIKAVYVKRRDVMLKTMEEEFPEGLVFTHPEGGLFTWVELPSN
                     LNAKELMPKCLDKNVAYVAGGGFFPNGGRENTFRLNYSNMPEEKIIEGIKNIAAVLKE
                     AMGVEA"
     gene            15765..16043
                     /gene="rpsF"
                     /locus_tag="ACGI5H_000735"
     CDS             15765..16043
                     /gene="rpsF"
                     /locus_tag="ACGI5H_000735"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420522.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0000314 - organellar small ribosomal
                     subunit [Evidence IEA];
                     GO_component: GO:0022627 - cytosolic small ribosomal
                     subunit [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S6"
                     /protein_id="HFG9696464.1"
                     /translation="MRNYELVYVVKPNSDEEVREAILNKVKEVVATDGEIVKVDTWGT
                     KKLAYPIAKFTEGFYVLVNFKSAVDVPKEIDRNLKINENVIRHMIVVA"
     gene            16080..16514
                     /locus_tag="ACGI5H_000736"
     CDS             16080..16514
                     /locus_tag="ACGI5H_000736"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420524.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded DNA-binding protein"
                     /protein_id="HFG9696465.1"
                     /translation="MNQVVLVGRLTRDPELRYIPGTGTPVASFTIAIDRDYVKKDGSK
                     ETDFIPVEVMGKSAEFCANYITKGRLVALQGSIRVDNYQTQSGEKRTFTKVSTRSVQA
                     LDSKNKSENSYRESAPAFEPSFEPQGLDPQGFQAIDDDDIPF"
     gene            16533..16760
                     /gene="rpsR"
                     /locus_tag="ACGI5H_000737"
     CDS             16533..16760
                     /gene="rpsR"
                     /locus_tag="ACGI5H_000737"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420527.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0000314 - organellar small ribosomal
                     subunit [Evidence IEA];
                     GO_component: GO:0022627 - cytosolic small ribosomal
                     subunit [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S18"
                     /protein_id="HFG9696466.1"
                     /translation="MMNKKRRKKKRVCQFCADKNAKIDYKSTQRLQKYITERGKILPR
                     RISGTCAKHQRELTVAIKRARNIALLPYTLD"
     gene            16903..17223
                     /locus_tag="ACGI5H_000738"
     CDS             16903..17223
                     /locus_tag="ACGI5H_000738"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420530.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MazG-like family protein"
                     /protein_id="HFG9696467.1"
                     /translation="MKIDKGSEITRNIKIIEWMKTEILMSVSDLFNLLFKGVKPLDEA
                     IQDTLANIIMITYLLAKRLGISFRDVDYKVKEKIKIGIDEDHSVERWYGDLSNLKKHM
                     DNRE"
     gene            17231..18187
                     /locus_tag="ACGI5H_000739"
     CDS             17231..18187
                     /locus_tag="ACGI5H_000739"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434254.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YybS family protein"
                     /protein_id="HFG9696468.1"
                     /translation="MNNKIRLSKAMSIIVLAIIIALVIAYIPMLGIFSMLAAVPYVII
                     GAITDRKYSLISILVTFCVLILFADISYALNICIMYSLPGIVIGKMLKRSFEQEDSNK
                     FEPIYGGTIIFVLSMLVYFFVLKTFLNVNLLDEVSKMISEIVNIQKNSFSATELKVFD
                     KMKPDEIVSYFTNMLPMMLFLQGLLSAFVTYYLSVFFIKRITKMNIRFPKFADFYLPG
                     NAILTTFLLYLLVLFIQIIGSKLYTELIMTNLQLVFNLMFVIQGIAVCIYFLKKWIRQ
                     GPNKIMFFSGIILCLFGFMGISFVGMVDSIIDFRKVRSYKST"
     gene            18198..20192
                     /locus_tag="ACGI5H_000740"
     CDS             18198..20192
                     /locus_tag="ACGI5H_000740"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420536.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DHH family phosphoesterase"
                     /protein_id="HFG9696469.1"
                     /translation="MSNKQTFKLNMPEINLYIIVIGISSIILLYYNLYVGCLFFCIFV
                     YMVFHNWRTTNIRRHEWTEYIQNLSLDIDETTKKAIINLPIPLCILEFDGNISWYNGK
                     FYDMIGQKDLLDKNIEDIVKNLNLRKVLNENKEMYTEINYKEKEYTIIYNVIKNDQEK
                     NPKYLMILYWIDKTEYLKVKQNYDDEKNAMMLIQVDGYDEVLKSAAEDKRALINVEVE
                     KILSALELNSNGALRRTSKDKFFLVMHKKELKKLEAEKFSILDTIRHIDYGNNLPVTI
                     SIGIGIDGDTLNENLKLATGALDLALGRGGDQAVVKTKDKFVFYGGKSKAVEKKTKVK
                     SRLIGHALREVIQQSDQVYIMGHKYPDMDAMGAAVGVYDICKSCNKTANIVLQSVNES
                     IEIFINKINENNYYKKLFIGKEEAIDNCTKNTLVVVVDTHRPNYTECEELLKLSEKVV
                     VIDHHRRGVEFINDAVLLFHEIYVSSTCEMVTELVQYMDEDVTINKLTAEGLLAGISL
                     DTKNFAFKTGVRTFEAASYLRKVGADTIEVKKFFNSDVKDFIIKAEIIQSTKIINNRI
                     CLAYSSTEIDSINVIIAQTADELLNIKEVEASFVLGEKDDTIFISARSLGQINVHVLM
                     EKLGGGGHIDIAGAQLKNVSLKEAYKMVNKIIEEYLEEEE"
     gene            20193..20642
                     /gene="rplI"
                     /locus_tag="ACGI5H_000741"
     CDS             20193..20642
                     /gene="rplI"
                     /locus_tag="ACGI5H_000741"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420538.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L9"
                     /protein_id="HFG9696470.1"
                     /translation="MKVILLKDVKGTGKKGEMKEVSDGYARNFLFPKKMAVQADSVAI
                     KELNEKNKSKEIKAQKEYEEAVLLGKQMEEINIEIYSKAGEGGRLFGSITSKEIAEQL
                     KKQKDIDVDKRKILLDEPIRSLGSTFVEIKIHQKVTTKIRVDVKEKQ"
     gene            20661..21989
                     /gene="dnaB"
                     /locus_tag="ACGI5H_000742"
     CDS             20661..21989
                     /gene="dnaB"
                     /locus_tag="ACGI5H_000742"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429266.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003678 - DNA helicase activity [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006260 - DNA replication [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="replicative DNA helicase"
                     /protein_id="HFG9696471.1"
                     /translation="MEDMTRIPPHSVESEQSILGSILLDKDAIITVTETIKPDDFYKE
                     AHKIIYECMITLSNKGEPIDLITLTEELRKQGHLNDIGGISYITSLSTIVPTTSNVKY
                     YADIVKEKSVLRKLIKASNEIINLGYSGATKIEDVLEQAEKSIFDISQEKTSDDFKSI
                     NLVLMDAYDMIEKLYTNKSDVTGITTGFKDLNKKINGLQRTDLILIAARPAMGKTAFS
                     LNLVQNAALKGDASVAVFSLEMSKEQLVQRMLSSQSSVELKKIKTGTLNDNDWPRIID
                     AMAVLSDAKIHIDDTPGIKISELRSKCRKLKIEKGLDLVLIDYLQLMEGEGNNESRQQ
                     EISKISRSLKILAKELNCPVVALSQLSRAPEQRADHRPMLSDLRESGAIEQDADIVMF
                     LYRDEYYHADSESKNIGEVIIAKNRHGETGSVELVWLGEVQRFGDKLRDL"
     gene            22194..22502
                     /locus_tag="ACGI5H_000743"
     CDS             22194..22502
                     /locus_tag="ACGI5H_000743"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011862026.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9696472.1"
                     /translation="MEKISLKYIYPNIIKVLDEINLFRVIDNNLRESIVVYANNVDNQ
                     YHINMTNTNFGNIINICKLEKLLDVDKFMEKVIKYEKEIIEKEEFSKIEEYMLNIGEY
                     "
     gene            22584..23873
                     /locus_tag="ACGI5H_000744"
     CDS             22584..23873
                     /locus_tag="ACGI5H_000744"
                     /EC_number="6.3.4.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420547.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004019 - adenylosuccinate synthase
                     activity [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_process: GO:0006164 - purine nucleotide biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="adenylosuccinate synthase"
                     /protein_id="HFG9696473.1"
                     /translation="MKTVAIVGSQWGDEGKGKVIDYLATQADVVVRGQGGNNAGHTLV
                     VEGKKYALHLIPSGVLNPNTVNIIGNGIVFDPKGFLEELEMFKTDNISTENIKISDRA
                     HVIFPYHKELDALSEEARGDLKIGTTKKGIGPCYMDKTERSGIRICDLMDKDKFAIKL
                     KAQIDAKNEIVKNIYGKEELFDFETIYNEYLGYAEQIRKYVADTSVIVYDAVRAGKKV
                     LFEGAQGTLLDLDLGTYPFVTSSHPTSGGFAIGAGIGPNMIKDVVGIVKAYTTRVGEG
                     PFVTEQINETGDKIREQGHEFGVTTGRPRRCGWFDAVIVKYAARVNGLTSISFMLLDV
                     LTGFDKIKVCTSYKMGDKIITDFPASLDDLAKCEPVYEELDGWNEDITQIDNFDDLPE
                     NAKKYVAKIEELVGVSVDMVSVGPNRAQTIIRRNIFA"
     gene            24199..24274
                     /locus_tag="ACGI5H_000745"
     tRNA            24199..24274
                     /locus_tag="ACGI5H_000745"
                     /product="tRNA-Lys"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:24232..24234,aa:Lys,seq:ttt)
     gene            24281..24355
                     /locus_tag="ACGI5H_000746"
     tRNA            24281..24355
                     /locus_tag="ACGI5H_000746"
                     /product="tRNA-Glu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:24314..24316,aa:Glu,seq:ttc)
     gene            24360..24435
                     /locus_tag="ACGI5H_000747"
     tRNA            24360..24435
                     /locus_tag="ACGI5H_000747"
                     /product="tRNA-Val"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:24393..24395,aa:Val,seq:tac)
     gene            24469..24543
                     /locus_tag="ACGI5H_000748"
     tRNA            24469..24543
                     /locus_tag="ACGI5H_000748"
                     /product="tRNA-Thr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:24501..24503,aa:Thr,seq:tgt)
     gene            complement(24926..25918)
                     /locus_tag="ACGI5H_000749"
     CDS             complement(24926..25918)
                     /locus_tag="ACGI5H_000749"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892306.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HFG9696474.1"
                     /translation="MNEDKIRKILAKYAKRRDDNELLLEHRKNEVYNRIPEIKSIDDE
                     ISKIGLSLAKIVLLNPKSKDEIVKKTKENIESLKVKKERLLAESNIPLDYLEIKFQCI
                     SCKDKGFLPNGEKCSCLKQEIVNEAYKMSNLDRILSQENFSNFNLNIFSPKKGSDGEI
                     SPRENMLNNLSICENFVHDFKKDNSENLLFYGSTGLGKTYMCNCIAKELLDKGNVVIY
                     QTSFRILDILEDYKFRRDTNNQISEDNYKNLFDCDLLIIDDLGTELNNSFTSGEIFNI
                     VNTRLVAGKKIIISTNLTPSQIGNTYTQRTLSRILDKFRILEFTGDDLRWERFK"
     gene            complement(25927..26985)
                     /locus_tag="ACGI5H_000750"
     CDS             complement(25927..26985)
                     /locus_tag="ACGI5H_000750"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420554.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DnaD domain protein"
                     /protein_id="HFG9696475.1"
                     /translation="MFFKESNEIDLGEITIPNIFIDIFMPMADGLYVKVYLLGYRQAC
                     DITSNPKFDNNSIAKNLNIPLSDVLSAWKFWEEKKIIKIHDNEEYDNFNYSIEFLDLK
                     NFYIENILSNNSSIKSNTDKVVSTSENPSIRKMFNSINKIVGRYLDPSEKMSIMDIMN
                     KYNMSPDMILCAYEYVKDKTGTSKPVKYIEGIIRNWYDSNLYTPKDVEESFLVRSERY
                     ILYKTIFNELGFSRQPSKSEKELMDTWFDKFNMDIDLIINACSKSKNISNPSISYING
                     IIKNWNEKNIKNLNDLKQKEEERIVKENINKKQINTTQNNNTYKKTKFHNFNETFTQY
                     TSDELDEIIKKSQKEKFK"
     gene            27110..28573
                     /locus_tag="ACGI5H_000751"
     CDS             27110..28573
                     /locus_tag="ACGI5H_000751"
                     /EC_number="3.4.11.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420558.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004177 - aminopeptidase activity
                     [Evidence IEA];
                     GO_function: GO:0008237 - metallopeptidase activity
                     [Evidence IEA];
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="M1 family metallopeptidase"
                     /protein_id="HFG9696476.1"
                     /translation="MVIKFNQKVRRTLSVAILFMVLIIGCFIEKDDSLETYKEKTNSK
                     INQYNMDVIFDDETKRLMCNQNVDYINNTKSNIDKIYFHIYPNAFSKKDFAPFEKSEM
                     TRAYPNGFNEGYIDIKNILNNNSKMEYKIKGDKNDILEIELGKELKPNERMSLDIKYN
                     VKIPNSIGRFGYGENTINVTNWFPIACVNDERGWNLKSYETIGDPFYSETSDFHVKLL
                     IPNKYKIAHTGKLIDDKHDNKKMLYEIEAENVRDFAFILSSKFDVNKVDSKGVAINTY
                     NLNKKLSKKATEVAKDSINIFSELFGKYPYKEFSVVASDFFIGGMEYPMLVMIDQSLY
                     NEKNEFLLEYVIAHETAHQWWYSAVGNDEISEPWLDEALTEYSTIVYFEQKYGKDMAN
                     KLIKTMEIQTKSYLSENIFKPANEYKNSTEYSLNVYTKGAIAFNEIRKEVGDKVFFET
                     LNEYYNKYKHKNANGRAFVELWNSKGVDINKIISECK"
     gene            28675..29472
                     /locus_tag="ACGI5H_000752"
     CDS             28675..29472
                     /locus_tag="ACGI5H_000752"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435698.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HFG9696477.1"
                     /translation="MLKYCSVGSGSSGNCHYIGYKNTNILVDAGLSGKRITTGLKDIG
                     VDADKLKGIFITHEHVDHIKGAGILSRKFDIPVFANIKTWCSMKDKLGDIKDKNMKVF
                     ENDKTYSLGDIIVRPFSIEHDASDPVGYNFYTESDEKMSIATDIGCITQNIKKHLYKS
                     KLVVLESNYDPNMLMMGSYTYALKKRVMSSTGHLSNEDAANFCVELINEGTESILLAH
                     LSKENNFPELAYETSKGVLASNDIVVGQDVKLDVLSRNDVSNVYEMK"
     gene            29485..31587
                     /locus_tag="ACGI5H_000753"
     CDS             29485..31587
                     /locus_tag="ACGI5H_000753"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429254.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EAL domain-containing protein"
                     /protein_id="HFG9696478.1"
                     /translation="MLKRNFENVEDNKILYSIKQGMILAIPAIMTGSTALVILNLPIK
                     AYQEYLSGLFNGEVTNILNFINDSTLGIISLIILLTISYSYGKIYGSKYTVLVPIVAM
                     CSFLVFSHGNELNSYIEIFKTKWLFTSIIVSMTSSVLFVKLTESFVTSVKFHTEGADA
                     DFNMVVSAIVPFIIVVFLFSIFRVVMISLIGSSNFQDIFYNLFSNVFNKMGTNLMSAL
                     LFIFLMHFMWFFGIHGSNVLDTVAKNLFENSMAININLVNNNQLPTEIFTKTFFDTMV
                     LLGGCGSLLCLVIAIFLSEKRINVRKLAKIASIPALFNINEMLVFGIPIVFNYIMFVP
                     FVITPIILTVTSYVAMSTGIVPCTVSAVEWTSPIFLSGYMSTGSIRGSLLQVFNLCVG
                     VMIYIPFIKMSQNRYTYMFKNNIENLTNLLKRYELTGEQPNLLNHNGKIGSISKMLAS
                     DLKFAMKRGEIELFYQPQVNYNGNVVGAEGLLRWKHSIGGFIYPPLVIILAKEEGFLD
                     ELGEYIINKACIDLKKSEKLLRNPVKFSVNISPDQLDDPKLPEQIKNIISSNDINPNM
                     LGIEITEQIALSGSQIIIERINAIHNLGIKLIMDDFGMGHSSLIYLQNNNFDIVKLDG
                     SLVKEILTNKRSSEIIMTIVNLSKNLDFDIVVEYVENIDQRDKLYGLGCEIYQGYYYS
                     KAIPFEEFVEYANQEREI"
     gene            31655..32134
                     /gene="rlmH"
                     /locus_tag="ACGI5H_000754"
     CDS             31655..32134
                     /gene="rlmH"
                     /locus_tag="ACGI5H_000754"
                     /EC_number="2.1.1.177"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435703.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008168 - methyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0006364 - rRNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA
                     (pseudouridine(1915)-N(3))-methyltransferase RlmH"
                     /protein_id="HFG9696479.1"
                     /translation="MNISIVVVGKIKEKYLKLGIDEFKKRLSKYCKLEIIELDDEKAP
                     ENLSVKEMEIIKDKEGKKILGKIKHNSYVIALAIDGKGLSSEELAKTMSDLAVRGNSS
                     LCFIIGGSLGLSDEVLGRADYRLSFSKMTFPHQMMRLILLEQIYRAYRINNGEPYHK"
     gene            32283..32594
                     /locus_tag="ACGI5H_000755"
     CDS             32283..32594
                     /locus_tag="ACGI5H_000755"
                     /EC_number="2.7.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HFG9696480.1"
                     /translation="MIKIMLACSAGMSTSLLVTKMESAAKENGIESQIWAIPESTIQN
                     EIEKCDVLLLGPQVRYVLPKAQEIAKPYNIPVEVINMMHYGTVNGEAVLNRAIELNNT
                     K"
     gene            32642..32959
                     /locus_tag="ACGI5H_000756"
     CDS             32642..32959
                     /locus_tag="ACGI5H_000756"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435715.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016740 - transferase activity [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose/cellobiose transporter subunit IIA"
                     /protein_id="HFG9696481.1"
                     /translation="MDEKTIEISFNIIGYAGEGKGLAFEAIKEAKNGNIEKAKELLKE
                     SREVINKAHRYQTELIQNEASGNRTEISVILIHAQDHLMNGMNFQQLAEEIVDLHLKL
                     QDK"
     gene            33172..33873
                     /locus_tag="ACGI5H_000757"
     CDS             33172..33873
                     /locus_tag="ACGI5H_000757"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435717.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HFG9696482.1"
                     /translation="MLRNQPLYIQVVDILKQKILNNEYKIDENIPTERELEQEFGVSK
                     ITIRKAIEILESEGYVEKKSGKGTKVISNSLFNKLSKAESFSSILLSKGHKLSKETIS
                     IEKIINDTNSQVFSIFGEKCSKITRMYYLDSKPYIFFTHYIPFDENLTVESFNNESSL
                     YMYLYRRNINITRFEDEFFIEESELEVSKALNLAKDILLGRKRKTYDENDNIVELSFA
                     RYNTEVQNYVIKYEI"
     gene            34097..35398
                     /locus_tag="ACGI5H_000758"
     CDS             34097..35398
                     /locus_tag="ACGI5H_000758"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892292.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HFG9696483.1"
                     /translation="MEKFASFLERKIMPVAAKISNQRHMRAVRAGIIATLPLTIVGSF
                     FTILLNIPIDAYMDFIAPFKAILDIPFRYTVGFLSLYATFGIASSLAKSYDLDTTGVG
                     MLAVMAFLVSTIVPTQVVEPVGGVIEAGRWMDMAKLNSPSLFGAIVTSLITVEIYRFM
                     KEKNITIKMPAGVPVEVSNSFTALLPTAVILMLFWVIRHILGFDISVALSAMLSPLKG
                     FLSGNSLGGGLLTVFLITLFWVLGIHGSAIMGPVIRPIWDMSIAENITAFTEGVSAHA
                     MPNIFTEQFLQWYVWIGGAGATLALVVMFMFSKSQYLKSLGRLGFLPGLFNINEPIIF
                     GAPIVMNPILGIPFIIGPIIMTILSYVLTITGVIPMMVARLPFAMPAPIAAVMSTNWS
                     ILAGILVLINFVISFAVYYPFFKVFEKQQLQREQEEMSENL"
     gene            35535..36629
                     /locus_tag="ACGI5H_000759"
     CDS             35535..36629
                     /locus_tag="ACGI5H_000759"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892290.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MupG family TIM beta-alpha barrel fold protein"
                     /protein_id="HFG9696484.1"
                     /translation="MERRLGISVYPEHSNMEDDKAYIKMASKYGFKRIFMCMLSITRP
                     KEEVKKHFKEIITYARELGFEVILDIAPNIFDILQISYDDLTFFSELNASGIRLDYGY
                     DGSKEAMISFNPYDLKVELNMSNDVAYLDNIITYKPNVNNIYGCHNFYPQRGTGLPYD
                     FFVRCSNRFKKYGIRTAAFVNSKYATIGPWNINDGLCTLEMHRNLDIATATKHLFATG
                     LIDDVIVGNAYASEDELKRMSEVNKYQVVFNVVTEEKTSEVEKTIMANEQHFRRGDIT
                     NQVARSTEVRKKYAKENFPKHDNTTIFKRGDVVIGNDDFGKYKGELQLILQDCADERK
                     NKVGRIKEDEIILLDFIEPWSKFKLILEGE"
     gene            36631..37764
                     /locus_tag="ACGI5H_000760"
     CDS             36631..37764
                     /locus_tag="ACGI5H_000760"
                     /EC_number="3.5.2.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892288.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005575 - cellular_component [Evidence
                     IEA];
                     GO_function: GO:0003674 - molecular_function [Evidence
                     IEA];
                     GO_process: GO:0008150 - biological_process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="amidohydrolase/deacetylase family
                     metallohydrolase"
                     /protein_id="HFG9696485.1"
                     /translation="MKIDILIKCGKTVDKSIIDIAILDDKIIEVKNQIDDSKYQANQI
                     INLDGEKFISAGWIDIHTHCYERLDLYKDYPDEVGIKSGVTTVVDAGTTGALDIGKFY
                     EDTKKYKTNVYALINIAKQGITSQDELSSMMNIDEYELRRAVKKYKDFVVGIKARMSK
                     SVVISNDVEPLKVAKRIKNELNLPMMVHFGSSPPTIEDIFDYMEKGDILTHIYNGKPN
                     GILRGNEVKKEIIEARERGIILDVGHGTESFSMDIAMKSKDAGIFPDTISTDIYIKNR
                     INGPVYNLSTTMEKFIYMGYSLEDIIDKVTKNAADAISLKNKGLIKEGYDADLTIFDV
                     VNEEKELQDSLNKSVITSTSIKPRAVVVNGEYLNIGKSIGENE"
     gene            37782..38891
                     /locus_tag="ACGI5H_000761"
     CDS             37782..38891
                     /locus_tag="ACGI5H_000761"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894111.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DgaE family pyridoxal phosphate-dependent
                     ammonia lyase"
                     /protein_id="HFG9696486.1"
                     /translation="MSSIFEKYSVRRVINASGKMTILGVSTVDKEVIEAIGEGCKNFF
                     IIEELINKTGEYIANLLGCESALIVSSASAGIAQSVGAMIAKDDMSLVYNVNNPKKQV
                     KREIIIPKGHNVDYGVPVEVMIRLGGGEVVEAGYANMCNKEHIIREINENTAAIMYIK
                     SHHCVQKSMLSVLDAVQVAKEYNLPLIVDAAAEEDLNVYYELGADLVIYSGAKAIEGP
                     SSGLVIGKKKYIDNVKLQSKGIGRAMKIGKENIVGLTCAIERYISNDKVTLKEMEDKL
                     NPFIDKINTIKGVSASITRDSAGREILRGEIDFNEDIINKSTQQIINELRSGEIAIYT
                     RDYKANEGKIEIDIRSVTGSDLDTIYNRIKNIVES"
     gene            38956..39696
                     /locus_tag="ACGI5H_000762"
     CDS             38956..39696
                     /locus_tag="ACGI5H_000762"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729158.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="KDGP aldolase family protein"
                     /protein_id="HFG9696487.1"
                     /translation="MNCIPQYYKNRVCLNVLAGSIKNAKEVYDACDGHVLIGILSKNY
                     STVEAAIEDMKKYSKEIDNAISVGLGAGDPNQSNMVSQISKELQPQHINQVFTGVATS
                     RALLGQNDSIINGLVSPTGKPGFVKISTGPLSSKEKDGIVPIETAIAMMKDMGGSSIK
                     FFPMGGLKTKDEYIEVAKACAKHNFYLEPTGGIDLDNFKEIVQIALDAGVEKVIPHVY
                     TSIIDKETGETKVEDIGVLYKIMKELLG"
     gene            39701..40693
                     /locus_tag="ACGI5H_000763"
     CDS             39701..40693
                     /locus_tag="ACGI5H_000763"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429232.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005829 - cytosol [Evidence IEA];
                     GO_function: GO:0019200 - carbohydrate kinase activity
                     [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sugar kinase"
                     /protein_id="HFG9696488.1"
                     /translation="MNILAFGEIMMRLSVPDYKFLTQTNELNYITTGTGLNILSGLKN
                     FGYNTYMLTKLPNNNVGKASSANIRKLGVKDDFITYGGNHIGVYFLENGYGERPSEVT
                     YLNRLNSSFCESKLQDYDIDKCLEEMDIVHICGIAMQLTDSVKEIALELARKSYEKGI
                     KVFFDFNFRQSLNPERTYDDLVNDYKKILPYCHGLFASYRDINKILNIDSLNIKSSSE
                     LIKKEYDIDIVAGTMRRFDDMNNRFIKGYISNDDGYFESREYKLEIYDRVGAGDGYVA
                     GIIYSYLENMKSEDIVEFGVASSVLAHTTYGDNSLVSTGHVLRLMNNEKIDILR"
     gene            complement(40881..41762)
                     /locus_tag="ACGI5H_000764"
     CDS             complement(40881..41762)
                     /locus_tag="ACGI5H_000764"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429230.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HFG9696489.1"
                     /translation="MNTKQLEYFISVAENLSFTKTAEKFYISQTAVTQQIKALEEQIN
                     VTLFTRSKRHVELTPAGKVFLSEARTIIKNINDAIAKTQQFAHGFFGTLSIGTLIGYE
                     KNKLQQYLKEFSNTYPNISMDICTNEITELLNLVKNNSMDLAFVINPENQPLKDFEYK
                     TVERYSLVALLPPGHPLYNEDSIDLIELQHDKFIFVKETGDEYGQKSMIQNRYREAGF
                     VPNVVQRSNNLNTIESLVSSNMGISILPSFCVTDTMIERDIAIVPIKEVENRIEVVVV
                     WNKKNTNPALEKFISII"
     gene            42035..43423
                     /locus_tag="ACGI5H_000765"
     CDS             42035..43423
                     /locus_tag="ACGI5H_000765"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729155.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LVIVD repeat-containing protein"
                     /protein_id="HFG9696490.1"
                     /translation="MEDKFYAKGNGNNGYIKNLEVCSFNNLDGTCGMFQMALYKRDEK
                     YYLYGCCFGGNKKNGVMISDITDPYNPQFIKHFQMLDPKEYPTTTTPKIQIADDLMIV
                     AMSCGSGPGALVDQAKLANIKCEAGIRIYSLKEDPLNPKFLGYWDCGLKHVMGVHRFM
                     YNGGRYVHLSSDCVGFEGLIYRVIDIINPTNPVEIGKWWRPDQYANGYPNRTFDAGAP
                     HCPEFMDKGWLHGPPFVRDGKAYCGYGGAGLVVLDVEDLTRPRCLGELPFMPAFSSRL
                     AGARTHTALPLPGRDLVVVQNEGERFQFFKPDNITDVQAMNNIHMVDVSDPTKPTLIA
                     QFPYPEVPKDFPYPNFNVAGLGKPGPFGPHNLHEPMDNKPWLEQRGDRVYCCYFHAGL
                     RVYDVSDPYYIKELAYFIPPNPNKTPEESYFPGFPGPRLAVTEDLIVDDRGYIIIDAL
                     DDGFYILKMKED"
     gene            43451..44404
                     /locus_tag="ACGI5H_000766"
     CDS             43451..44404
                     /locus_tag="ACGI5H_000766"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729154.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0009055 - electron transfer activity
                     [Evidence IEA];
                     GO_function: GO:0010181 - FMN binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="flavodoxin family protein"
                     /protein_id="HFG9696491.1"
                     /translation="MKILGISFGTKNGNNDTMCKVALKGAKEAGAEVEFIQMSSINIK
                     HCTGCCACVKTLLSGKGSMCVLKDDFEWLLDKMKDADGIVVSDPIFEEGASGLFHTIM
                     DRFGPRADRGNNIIGTKVAEAIGGKIPDSRMLNDKVISFMGIGGSDWGTRVQCEHAML
                     ALIPMWKVIDNAWFPWAKELVMDDTRLVQVHQIGLNIVEAAKDFEKASYQGEEGVCPH
                     CHNRLFYLEPGTKKAICALCGIVGELDTISGKTIFSFPEEQLGHAHDTLPGKFIHGDD
                     IKKMEGHYAEVRKTQEFKERKTSYNFIEPLTKEKQAGVSLG"
     gene            44464..44688
                     /locus_tag="ACGI5H_000767"
     CDS             44464..44688
                     /locus_tag="ACGI5H_000767"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429224.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9696492.1"
                     /translation="MNEKSSFKQIEIILAVIFLVLTYYKVRLTPAFIVIFIPLYLSYF
                     AVSMIVNQIAIKLLEIRQAREATNYNIGNG"
     gene            44681..45193
                     /locus_tag="ACGI5H_000768"
     CDS             44681..45193
                     /locus_tag="ACGI5H_000768"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894099.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1097 domain-containing protein"
                     /protein_id="HFG9696493.1"
                     /translation="MDRKKKEILTLSMGIALLPPLWAVLAPYIGIKTGAVALICAGLY
                     VTNGNKQKDGLKIMFGFWCGDLWAVLAILIMGYMNFNQNLELFLTLSILGFFAVVIAS
                     LFEKIIFLPSWLCGWAIGLTIMTGENIINLQDICIQIAVAMAVGVWYVGAGVDLFTIY
                     ILSKDRKKGN"
     gene            45225..46079
                     /locus_tag="ACGI5H_000769"
     CDS             45225..46079
                     /locus_tag="ACGI5H_000769"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011862019.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA hydrolase"
                     /protein_id="HFG9696494.1"
                     /translation="MAMGFEFKIMRSLIYVGLAKEEYRPKLMDWLYRHHIPDSISTFG
                     PYCTKYAFYQAYPTPNEGERFGARKMQLTEHYWLVDEHMPEMANRIMTEYMPMDVLRW
                     QGCIPDVENKRVHENAESGDAGRAVGGDNGCPPFIFAFVPINWEEDFRGKGRTVQDGP
                     NYRWQFMIKYPDGISKEEGEKWFYDEVVPYFTNCCYVNRFVSSKIMINYGATAFDRVS
                     ELWFEGEEEWYKAVVEETKSFIKKPEWAQEEEFPYLKPQFNIASVFLGDIATMDAYSQ
                     YRGYIPMR"
     gene            46613..47407
                     /locus_tag="ACGI5H_000770"
     CDS             46613..47407
                     /locus_tag="ACGI5H_000770"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435749.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HFG9696495.1"
                     /translation="MYTIGQVSKFLGISRDTLKFYEDKGLVNPKKNDENGYRIYNQVD
                     IYDIATINFYREIDIEIKKIQEIRKSKSINNLELLLEEKEQIILKEIEYKKLLLKKVQ
                     LVKEDCDKIKTYFGKYTIKEMKPLEVKGKIKHVTNYEEYEALKENTNNLKKAVTLTDL
                     RRVINFNEEGIIEEKFIIVREVDDYNKIIEGEVLSHPNCIYTIIEDGRWSTGGENIDN
                     KVEDRLREIAIENECELLGIVYVNILLTTYEEGIERIFLEIYAPIK"
     gene            47511..48317
                     /locus_tag="ACGI5H_000771"
     CDS             47511..48317
                     /locus_tag="ACGI5H_000771"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011862018.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II CAAX endopeptidase family protein"
                     /protein_id="HFG9696496.1"
                     /translation="MRTEKSLKRPIASFIILTNIIFLPLFLLVVVTIMLKLPTVISDI
                     ALCISAWSSTFAFMILFKKIYPGKKFLVHVKDRFRNKLKFSTVSIIISIQVLIAVVVI
                     FILASKNHGIMPNFTVSSWGAFIYLFLKNLFAGSLGEELGWRGFVQNHLQKRHSPLKA
                     SIIVGFWWGMWHLPIWFTTGFKGLDLIKYIIFFMIAIISISIIMTTFYNLNKTLIIPI
                     VIHQLFNFLIGIINGDLIELINYYAMLYLIFAIALIVINPGNVLYKNIRE"
     gene            48379..48900
                     /locus_tag="ACGI5H_000772"
     CDS             48379..48900
                     /locus_tag="ACGI5H_000772"
                     /EC_number="3.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429214.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine hydrolase family protein"
                     /protein_id="HFG9696497.1"
                     /translation="MVLLIVDAQKLITNERLYKFNEFVVNVENLIDTARKNNIEVIYV
                     RHDDGVENELTKGKNGFEIYEKFKPCNGEKIFDKKVNSAFKETGLLEYLTNNGEKDII
                     IAGLQTDYCIDATIKCGFEHGFNIIVPAYSNTTVDNFFMSAEQSYKYYNEFIWNERYA
                     KCISLEETLRKMK"
     gene            49315..51402
                     /locus_tag="ACGI5H_000773"
     CDS             49315..51402
                     /locus_tag="ACGI5H_000773"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011862017.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antiterminator"
                     /protein_id="HFG9696498.1"
                     /translation="MVVDKEIVSILQILLNSTLITTNGLQEESNSSKRQITYRINKIN
                     DMLKVKNVPLICLRADKDIIVRKETKKAIKEILEKNYSKNTYYFSKTERLLYMYLMLF
                     INMDDISINHFINSIKVSRSTVNLDFKDLIPELEKKNIKVKNNRINGYYIVGNEMEIR
                     RVLIKNIIETLSNEKSSRVFDIFIKEYNLDSFEEAKKIILKLIKKYEITFVEDRLVEF
                     IYIFIFLKARMYSTRIVTQENVDIPNISVMSSMKEYKFAKELLEVYGSEDKIKPHNIM
                     YISAWILGISVGNYEEDTEDKDVISKIVNKMMTKFGYLSGVYYISQEKIFKQLYSHFR
                     PAYYRLLFKLPIYNPICEKVKEEYKLVYRIVSNAMKEFCGLFGEEIQEEELAYLTMHF
                     ATLFSNKKEFDGFRKRIALIVCSNGVGSSAILHAELTNLFPDLHFIPMSESVGLENIS
                     EPVDIVFTTNYNAEGLKTDVPVIKVSPVMTTKEKYKITREVYIQLGDIFLRQPKIDEV
                     MDIIKKYANVTSESILSSELLAYFTQIENFTSKEGEGPMLSEITNETLVKIKVKAKNW
                     EEAIRQSASVLVENNKVTEGYVDAMINSAKASGPYIVITKHVALPHARPEAGSKEIAI
                     GIATLDSPIEFGNNENDPVKYVFCLSAIDNNSHLRAMSELVELLEEDEFFKVLDSAKE
                     AKEIIDFIKTHEL"
     gene            51417..51704
                     /locus_tag="ACGI5H_000774"
     CDS             51417..51704
                     /locus_tag="ACGI5H_000774"
                     /EC_number="2.7.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420619.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HFG9696499.1"
                     /translation="MYKILIACRAGVGSSLMLKIKTQQIIKENNFPIEVEHGSLDSLN
                     GFNGDAVETLIDVAEELKNKNLKFDIIGIHNIVDRNEIKTALEKFLASKEG"
     gene            51731..53002
                     /locus_tag="ACGI5H_000775"
     CDS             51731..53002
                     /locus_tag="ACGI5H_000775"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420622.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS ascorbate transporter subunit IIC"
                     /protein_id="HFG9696500.1"
                     /translation="MEFIISLLSTPAVLLGVVACIGLILQKKSAVEVFTGSSKTLIGF
                     LIFGIGASAMTGALQNFNKLFQHGFGITGVIASPEAATALAQGTYGFAVSCTLILGFI
                     LNLVFARITKFKNIFFTTGHSLFFSCVLVLIMKAHGFDNTITILIGGTILGFMSAALP
                     QFCQPFMRELTGGDEQAIGHFNMIGYGLSGYIGRLFSKHKDDTTETIEFPKWLSIFRD
                     FLMGLSIVMLILFYIATLKAGQAFTQEIAGSTHWLVFPLIEAFTFVAGMSILMSGVRM
                     FLAEITAAFVIISEKYIPGSRPALDVPTVFPYAPNAVIIGFISAYAAGLLAIAIMASF
                     PSIFPVVIIPAAHICFFSGGTAAIFGNTSGGWRGAIAGSFVVGLLLAFLPVILYPVYG
                     TLGIEGATFPNIDYNVVGSILHNILQFIKPI"
     gene            53060..53659
                     /locus_tag="ACGI5H_000776"
     CDS             53060..53659
                     /locus_tag="ACGI5H_000776"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0097367 - carbohydrate derivative binding
                     [Evidence IEA];
                     GO_process: GO:1901135 - carbohydrate derivative metabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="SIS domain-containing protein"
                     /protein_id="HFG9696501.1"
                     /translation="MENTLSEFLDNISNELSEFIASIDETSINKACELILEAEKNHGR
                     VHVTGIGKPGHVSGYISSLLSSTGTSAYILHGTEAVHGSSGQVVEGDVVIAISNSGET
                     QELKATLKTLKVNGAKIIGVSGNESSFLKNISDIFLFAGVKQEGDCLNKAPRASILAE
                     TIILQSLSVVLQYAKGLNTQEYLKWHPAGSLGKSIREGI"
     gene            53664..54569
                     /gene="dapA"
                     /locus_tag="ACGI5H_000777"
     CDS             53664..54569
                     /gene="dapA"
                     /locus_tag="ACGI5H_000777"
                     /EC_number="4.3.3.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894092.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008840 - 4-hydroxy-tetrahydrodipicolinate
                     synthase activity [Evidence IEA];
                     GO_process: GO:0009089 - lysine biosynthetic process via
                     diaminopimelate [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="4-hydroxy-tetrahydrodipicolinate synthase"
                     /protein_id="HFG9696502.1"
                     /translation="MKYKGIICAMITPFDENQNINSQATCQLIDYLIEKGIYGLFILG
                     TNGECHVLTDDEKVEFAKIVINHTNNRVPVFVGTGGNSTREVVDLSKRMEAIGASALS
                     IITPYFVTPTQQELILHYKTIANSVNLPIIMYNMPGKTGINIEPESVRELSKIKNIVG
                     IKDSSGKLDNMKAYIEATKNENFSVFSGSDSLILDSLKAGSQGAVAATTNFLTEIGIS
                     IYENFMKGDLEEAQKSQSSIEELRRILKLGTIPSVMKKTIVLNGINVGTARLPVTEPT
                     GEVLEEIKRVVENYRTILNKSSENR"
     gene            54675..55307
                     /locus_tag="ACGI5H_000778"
     CDS             54675..55307
                     /locus_tag="ACGI5H_000778"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892267.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ketohydroxyglutarate aldolase"
                     /protein_id="HFG9696503.1"
                     /translation="MKKMNITKRMSECGALAIVREENLNRACEIAEGCIKGGITVIEM
                     SYTLNNAGEIIQGLNKKYGEILCVGAGTVLDSETARHAILHGAQFIIAPNYNEGVAKI
                     CNRYQIPYAPGCTSLTEAVDALSLGATFIKAFPISDFYGPKLVKVFKTPIPDMPVLAS
                     GGLNIENLHIWLENGVDVCGFGGLLTKGSVEDIAKNANKIREIIKNVRKI"
     gene            55784..58291
                     /locus_tag="ACGI5H_000779"
     CDS             55784..58291
                     /locus_tag="ACGI5H_000779"
                     /EC_number="2.7.7.65"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011862014.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diguanylate cyclase"
                     /protein_id="HFG9696504.1"
                     /translation="MKEDIRLHRMCKKEQATKNEVISEDILKSMSIGVSKHFLDDSFT
                     IIWGNTSFYQLLGYTEEEFLVKFSSLKDYYEQNLYHFESMKNHFLEAYHHGEKSIEYQ
                     ICISANNGDPVWVIMTGILIESQDNEKSMVYILYSKINELKIKQEELSDMEKESTENF
                     KWMMSEYAGNVYISDMDTYELLYLNKHSCNTLQASANELIGRKCYEVIQGRTSPCPFC
                     TNSYLKKDDIYEWEFYNKKLKRTFIIKDRMLNWQGRRVRIELSYDMYSAEYKLAKKDQ
                     ERESILKTIPAGMVRLDARDYLTILWCNDIFLNMIEYTKEQFAEELNNQCGYLFSEDY
                     KRSKKLAQDLKESGDNVVFEAKIYTRSREERIWTVTLCYISGEDSWDGIPSFYSIGID
                     ITKERKQIEKLQHISEKDALTGIYNRAETERQIKKYFEKNLNVMGALFMIDTDNFKQI
                     NDTEGHMIGDIVLTEMASGMKKIMRDSDVVGRIGGDEFTIFMKNISSVKDAEKKAEEL
                     LYMFRHLFQKEKSFLKVTCSIGIAIYPKDGTTFKEIYARADKALYQAKNMGKNNYVIY
                     NQDYFKELEEFDCSSLGTVIDSEKQYAEYPDNLTRYIFRMLYQTDDIDQAINMILEVV
                     GKQFDVSRVYIFENTEDGRYTSNTYEWCNEGISSQMAYLQNSNYQDYEDYEKLFEDEL
                     VFYCRDIHTLSPKLEELFSSQGIHSTLQCAYKEDRVFSGFVGFDECTGLRLWSQEEIS
                     TLSLISQIISMFLQRKKNNKLNQQIQQYQNILDNIDQCICVINKENNFLLYVNKKFKN
                     TYSKFQIGQPYYLDSIDIHKISIIWNKKEAYLCTSTI"
     gene            58633..60795
                     /locus_tag="ACGI5H_000780"
     CDS             58633..60795
                     /locus_tag="ACGI5H_000780"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435766.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1430 domain-containing protein"
                     /protein_id="HFG9696505.1"
                     /translation="MKKIIYVLFTIELLIVSLLGLNIVKDNEINNILYNDTTSISVMF
                     KDYKKLNKNYSKWIKDIADENNVAISKYVFNNNEKLSIYTTDTSLNNNIKLKSGKFPN
                     TNSNEFISNINTNNSNQVGKFSTMSKDISILIRDFGKISEVGESGILYISTQNEDTIN
                     KILRELNVDRSIFVARLHDRYVNSNLYLNPSIIRDLILIILCFLATIIHYSISVSREA
                     SILRLNGYSKLDIIARVIKNILRIMILSSVTALLIYIIYILKLNIGVRACLYFAMFSI
                     ICILINILISILIVGFNSRSSKYVLSLNGKKSYGFVNIMHFTLKIVFVSFLILSINNC
                     ILNYNMLQTQLGNLSEWDKAKNVYNLTLKDTGEQSLGKEEVIKNAKIKGFYKNLVEEK
                     DAFLIDSTNFEKLEDGSYMYEINSKGKNPEVSQYGKNIKINKNYLKVNPIYSNGKEIF
                     NLIDYDDKTINLLVPKKLQVHENEIKKEFRELFYFEKIEVENMYNKELNRELNKTKKS
                     DLNVNIIYVDNNQSYFTYNSLVMDDNRNLIDDPIAIVDIDNIDDSFYLSYISRCVYFN
                     SKKLDALADISSIIEAQGVEAHIQSLHAVYNEYGLEINKLEKYLNSEIFTIIIIAISN
                     LMITYNIVASYYERNKYKLYIKKIFGYSTTARSMLLIVSLILTNIIPIGIISTRVDLS
                     NNIILFGLLILVIEVIVSIVLDKIISNSSFNKIIKGEH"
     gene            60800..61417
                     /locus_tag="ACGI5H_000781"
     CDS             60800..61417
                     /locus_tag="ACGI5H_000781"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892262.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HFG9696506.1"
                     /translation="MISLINISKKFKDKSIIDKFNLEISKGEFVAITGNSGSGKTTLL
                     NIMGLLEKPNSGDIIINNIKNPNSKQIRILQRDFYGYLFQNYALIENENVENNLKIAL
                     KYQKNINHNEKINYALESVGLRKYNKKKIYELSGGEQQRVALARVILKECEVIFADEP
                     TGNLDKKNRDIVFDILKSLNKNGKTIVFVTHDLDLSEQADRVIKL"
     gene            61606..61950
                     /locus_tag="ACGI5H_000782"
     CDS             61606..61950
                     /locus_tag="ACGI5H_000782"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429203.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc ribbon domain-containing protein YjdM"
                     /protein_id="HFG9696507.1"
                     /translation="MENLPNCPKCNSEYTYEDGTLLVCPECSHEWALGLGAEEDSNII
                     KDVNGNVLNDGDSVTVIRDLKVKGSSSSIKIGTKVKNIRLIHDSSDGHDIECKIDGFG
                     AMKLKSSVVKKA"
     gene            62520..63386
                     /locus_tag="ACGI5H_000783"
     CDS             62520..63386
                     /locus_tag="ACGI5H_000783"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898806.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pentapeptide repeat-containing protein"
                     /protein_id="HFG9696508.1"
                     /translation="MIDIHKNIYDNKLFEELKIDCKKCFGLCCVALYFSASDGFPINK
                     ESGKPCINLQPDFKCSVHNSLIKRGFKGCTAYDCFGSGQKVAQVTYKGIDWMQSPELT
                     NQMSEVFLIMRQLHEMLWYLKEASVLNISDTIKSKIDLIIEETEKITNMGPEQIINLD
                     IISHRTKVNLLLSQASESMMGKVKSFIKTSTLKNMKKLSKNIDLIGADLRKINLIGAD
                     LRGRFLIAANLRNTDLSGANLIGADLRDCDIRGANLENSIFLTQLQVNTAKGDSSTKL
                     PASLIRPKYWEK"
     gene            63499..63903
                     /locus_tag="ACGI5H_000784"
     CDS             63499..63903
                     /locus_tag="ACGI5H_000784"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429200.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YmaF family protein"
                     /protein_id="HFG9696509.1"
                     /translation="MSYQNYKCERDYVYDDYKYNKCNKCYNDYEEMTHVHEYSESVKL
                     AEECEDRHNHRAAGVTGEVIPINGGTNHVHKINDNVDFLDHFHKICVTTGPAIRIPGT
                     DKHIHLICGETTVNDGHCHKFLFTTQIEAPLV"
     gene            64067..64516
                     /locus_tag="ACGI5H_000785"
     CDS             64067..64516
                     /locus_tag="ACGI5H_000785"
                     /EC_number="2.3.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011862010.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016747 - acyltransferase activity,
                     transferring groups other than amino-acyl groups [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HFG9696510.1"
                     /translation="MKSGIILEMKQINSTEYDEMLQVWESSVRATHDFLTEKDIESLI
                     PLVEIGLKEVENIVCIKDNDIIKGFIGIDKDKIEMLFIEDKYRGNGIGKKLIKYAIDK
                     YNVKYVDVNEQNKKAVGFYIHLGFKVFDRSEIDGQGNPFPILHMKLI"
     gene            complement(64672..65049)
                     /locus_tag="ACGI5H_000786"
     CDS             complement(64672..65049)
                     /locus_tag="ACGI5H_000786"
                     /inference="COORDINATES: protein motif:HMM:NF018663.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HFG9696511.1"
                     /translation="MLTPYLIFNGTCEKAFNFYAEAFGGGKTIFARLDSNPNNPIMHA
                     SVTFTKYEGCIMGADTDKPVVISGMAICVVLPSREAIEEISVKLAEGGTLVQEFLPHP
                     PPHQNDGAAEVLDRYGYTWYLST"
     gene            65320..66228
                     /locus_tag="ACGI5H_000787"
     CDS             65320..66228
                     /locus_tag="ACGI5H_000787"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898803.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2268 domain-containing protein"
                     /protein_id="HFG9696512.1"
                     /translation="MNIIEIRSDKIYKKIMDAPINKKEDIYRYELMKPFEFKWKCMNV
                     PIVARQKGGYDVIIASEMLGVLSPKDIDEKQKKNINVLSADKIWGTCKETIENSINAF
                     IKEGYDLNIKDYKYSILLANPNSPYTILSDGYWGDGGIPGYIFLSLVPNEYTINRLPV
                     LIAHECNHNIRFQFIEWNNNITLEEMMINEGLAENFATWMFGEEMLGPWVSRTDIETL
                     NTYIKPIIKSALKETGFQNITSYLYGDDIAKMQGYFPVGLPYCAGYACGYYMIKYYLE
                     KTNKSIIEATLLPYSEIIEAVKEFWE"
BASE COUNT        26272 a         7149 c        11754 g        21277 t
ORIGIN      
        1 aaataacata aacatacaat aaatggtgat tataactaga gtattgtcag taatcttaaa
       61 agttatacac aaaagtatcc acaagctgtg aataatttct aataagttga taacatttat
      121 gcacattatc aacaagtata tttataatat caaaatatat gtcaaacttc aatgatttgt
      181 aactaattta tccacaatat taactaattg ttgataaaaa tataaacatg ttaaaattac
      241 tttatttgtg tatataattg aaaaaaataa tttagaataa aattaaatag atttttacta
      301 gtattttcaa taaaaaaaat acataatata tatatggtag attttgtgat ataagcgtcc
      361 caaaaactcg ttgacaacag tagtaaaagt atttataatt atatgtgtta tgtttacttt
      421 gagggtaaag ttattatttt tataaacgga aaataaaatc tgaaaggcgg tgcaaaataa
      481 tgagtaaaag aacttatcaa ccaaaaaaga gacaaagaag taaagaacat ggtttcagaa
      541 aaagaatgaa gacgtctaac ggaagaaacg tgttaaagag aagaagagct aaaggaagaa
      601 atagattaac tcattaatta caaaagggcc gctgcaaagg tggccttttt gtgtaaataa
      661 ttacaattca tagctgtgtt tatggaggtt aactatggac tttaatagga ctaaagggtt
      721 gaaaaaagac tctgatttta gaaaagtata taaacacggc aaatcttttg caaacaaata
      781 tttagtaata tatatactta aaaataaatc agattatagt agagtaggta tttctgtttc
      841 aaaaaaagta ggaaaagcta ttactaggaa tagagtaaga agattaataa aagaagccta
      901 cagattaaat attgatgaaa aaattaagcc tggatatgat atagtattta tagcaagggt
      961 atctagtaag gatgctactt ttaaagacat agacaagtct ataaaaaatt tagttaaaag
     1021 aacggatatt tctatttaat tgtatgctat aaatatggag gttaatgact ttgaataaaa
     1081 taatttatat attaaaggaa ataagtaagt atttatcgaa tttatgtatt tatttagtga
     1141 gattttatca aaagtatata tctcccttaa agggacctac ctgtagattt tatccaactt
     1201 gctcacaata ttcaatagag gcgtttaaga aatatggatt tgtaaaaggt atgtatttaa
     1261 cgataagaag aattttaaaa tgtcatcctt ttcatccagg aggttacgac cctctaaaat
     1321 aaaagagagt aactattagg aggtataaaa aaattgaata taataggaaa tttcttagga
     1381 ttgattctta aggtaatatt tgaatttgtt aatcattatg gtatttctat aatacttttt
     1441 acgatacttg taaagattat tttattacca ttaacaatta agcagactaa gtcaacaaag
     1501 gcaatgcaag atatacaacc tcgtataaaa gagatacaag aaaaatataa aaataagcca
     1561 gaaaaacaaa atgaagaaat tgttaagtta tatggagaag ctaaaattaa tccactatct
     1621 ggttgtttac ctttattaat acagtttcct atattaatag gattatttag cgttttgaga
     1681 gaaccagttg ctcatggcgt ttttgcaaac aaagctgcat ttttagcagc tgacaatggg
     1741 tttttatgga taaaaagctt aacatcacca gattatgtat tagcagtatt ttcaggagca
     1801 agtgcatatg tcatgcaaaa agtaatgaca ccaaaagatc agttacaagg ctctatgaaa
     1861 gtaatgacat atgtaatggc aggtatgtct ttctattggg gatttatatt cccagcagga
     1921 cttacattgt actggacagt aagtaactta ttctcaatag ctcaatatta cttaataatg
     1981 aatcctttaa aagctaaact ggctgctaac tctaaggagg aaaaagttaa tgagaaaaag
     2041 cctaaaatta ataaaaagta agagtaaaga ggaagctata agtaaagcta tagcagagtt
     2101 gaatttaaaa gcagaggata tagaagtaga aatacttgaa aatccaagta aagggttttt
     2161 aggttttata ggtgctaaag atggtactta tgaaattttt gttatcgaga gggaagtaga
     2221 tgtagctaaa aattttatag aggtaatgtt gaaaaatgca aatgttgatg ccaaagtcaa
     2281 tgtatctcaa aaagataatt taatcatggt tgatattgaa ggcaaagaag ctgcaagttt
     2341 aattggtaga agaggggaaa ctttagattc tattcaattt ttgactggat tagctcttaa
     2401 taaaataaat aaagattctc atacaagagt acttgtagat atagaaaatt atagatcaaa
     2461 acgagaagaa tctttaataa gatatgctaa taaagttgct agagaagtag cgaaaacaag
     2521 aaaaactaaa aaattagatt atatgaatcc atatgagaga agaataatac attcagctct
     2581 tcaaaatgac aaatatgtaa ttacatatag tgaaggaacc gatccatata gaagattagt
     2641 aattgagtgt aaaagataaa gtcaacctcc taaacattag ggggttttat tttttaatat
     2701 tattaaatca ttaatgattg gttaaatgta aatctatatg taaaaaatta tgaattaaga
     2761 ggtgataaat ttgtttatag atgatacaat tgcagcaata gctacagcac ctggagaagg
     2821 tggtataggt atacttagaa taagtggaga aaaagctttg aaggttgcag aagaaatctt
     2881 taaatctatg tctggaaaga gtattgaaga atacaataag agaacattaa tatatggaaa
     2941 tatagtggat aatgaaaata taattgatga agttttattg gcatatatga aaggaccaaa
     3001 ttcctataca ggagaagatg ttatagaaat taattgccat ggtggattta tttcggtaaa
     3061 gaagatatta gaattaatac tatcaaaaga tgttagatta gcagaggctg gtgagtttac
     3121 taaaagagca ttcttaaatg gaagaataga tttatctcaa gcagaggctg taattgatgt
     3181 tataaaagcc aaaactgata tagctcatga agttgctcaa aatcaattag aaggttcttt
     3241 atcaaagaag ataagagaat tgagagataa agtcactgag atattagctc atgtagaagt
     3301 tgctatagat tatcctgagg aagatattga gcatataaca tatcaaactc ttaaagaaaa
     3361 aactgatgaa cttaaaaaag acattaaaaa attatatgat acagctgaaa gtggaaaaat
     3421 acttagagaa ggcttaaaga cggtaattgt tgggaaacca aatgtaggta aatcttcact
     3481 acttaattct attttaggag agaatagagc aatagttact gatataccag gaactactag
     3541 agatgttata gaagagtttg taaacataaa aggtatacct ttaaaaattg ttgacacagc
     3601 aggtataaga gatactgatg atattgttga aaaaataggt gttgaaaagt ctaaagaatc
     3661 atttactagt gcagatttga tagtaatggt tttagatgca tctagaaagt tgtcagaaga
     3721 agatatagag atattagaaa aacttaagga taaacaaaca atagtgctgt taaataagaa
     3781 tgatttgaaa caagagattg aagaagaaaa aatacttaaa tatgtagaaa ataatagtat
     3841 aataaaaata tcagctttac aacaagaagg aatagaagaa ttgcaagata aaatagagtc
     3901 tatggtatat aaaggtagta tcaaaaataa ttctagttta gtagtaacaa attcaagaca
     3961 taaagatgca cttagtaaag catataaatc tgcaacagat gctttaattg ctttggaaca
     4021 aagtatgcca tttgactttg tagaagtcga tttaaaaaat atatgggact atcttggata
     4081 tattaatggt gatacagtaa cagaggattt actagataat atattccata atttctgtat
     4141 tggtaagtaa tgtacaaaag taaacttgtt tttattatag agatttttaa aaaatttgaa
     4201 gtgtttctca tgaaacatta attttgaaaa gaaaggaatt ataaatgata aagtttgaag
     4261 caggaaaata tgatgttata gtagtcggag caggacatgc tggatgtgaa gctgctttgg
     4321 ctactgcaag aatgggatat aaaactttga taataacaat gtctttggat tccatagcat
     4381 taatgccttg taatccatca attggaggga ctggtaaagg tcaattagtt aaagaaatag
     4441 atgccttagg tggtcagatg ggattaaata tagacaagac atatatacaa agtagaatgt
     4501 taaatactgc caaaggtcca gcggtacact ctttaagagc acaagcagat aaatttaaat
     4561 atcatgaaga aatgaaaaag acattagaag atgaaccaaa tcttgatata gctatggatg
     4621 aagttgtaga aatacttcat gaaggaaatg ttgtaatagg agttggaact aaactaggat
     4681 gttcatttaa atctaaagct gtaatattgg ccactggagt ttatctgaac tcaaagatat
     4741 atatgggtga agttgcattt tatgaaggtc ctaatgcatt ggggtatgca aaatatctta
     4801 cagatagctt agttgagctt ggccttagaa tgagaagatt taagacggga actccagcaa
     4861 gagttcatag agatagtata gacttctctg taatgtcttt acaagagggt gatgaaaaag
     4921 taactccatt ctcatttatg aatgaaaata tagaaaaaaa acaagaacct tgttatttaa
     4981 caagaactac agaagaaact caaaaagtta tactggataa tttaaaaagg tctgctatgt
     5041 atagtggagt aatagaaagt actggtccaa gatactgtcc ttctatagaa gataaagtag
     5101 taagatttag tgataaaaca tcacatcaat tatttataga accagaaggg ttaaatacta
     5161 aagaaatgta tatacaagga atttcaacta gtttaccttt tgaagttcaa ttagatatgt
     5221 acaaaactat aaagggactt gaaaattgta agataatgag acctgcatat gctattgaat
     5281 atgattgtgt tgacccaact caactaaaaa taagtttgga aataaagggt gttgagaact
     5341 tatttagtgc agggcaattt aatggaactt ctggatacga ggaagcagca gctcaagggc
     5401 ttatggctgg tataaatgca gttagaaaga tagaaggaaa agagccattt gtattagacc
     5461 gttcagaagc ttatataggt gtcttattag atgaccttgt tactaaagga actaacgagc
     5521 cttacagaat gatgacatca agagcagaat atcgactata tttaagacaa gataatgcag
     5581 atatgagatt aactcaaaaa ggttatgata taggattagt taaaaaagat agatatgaaa
     5641 ggttcctaaa taaaaaggct gctgtagaga aagaatttga aagactaaaa aatgaaagag
     5701 ttacaccaaa agaagtaaat agtttgttag aagaaaaagg agcaacacca ataaaggttg
     5761 gaatatctct atatgaattt ttaaagagac cagaggttac ttacgaattg cttgaagaat
     5821 tagggaaagg cgctggagaa gatgtttcaa gagaagttaa agaacagtgt gtaataataa
     5881 ctaaatatga aggttatata gagaaacaat tgaaacaaat agaccaattt aaaaaacttg
     5941 agaataaaaa gctggatgag aaaataaatt attcatctat agaaggtctt agattagagg
     6001 ctagacagaa actagatgat ataaaaccta tttcaatagg gcaagcatct cgtatatctg
     6061 gtgtttctcc agctgatata tcagttttac ttatatacct agaacaaatc agaagaacta
     6121 gaggtggcaa aggtgaataa tatagaactt ctgaaaaacg ggattgaagg ttttaatata
     6181 gatacgaatg acagtatgtt agaaaaattt aaaatctata gagagatatt agttgactgg
     6241 aataaaaaga tgaatcttac tggaatagaa gatgaaaaag aagtgtatat aaaacatttt
     6301 ttagactcta tttcagctgt aaagaatgga tatataaaaa atgggatgtc tataatagat
     6361 gttggtacag gtgctggttt tcctggaata ccattgaaaa tatgtttaga tagcttagaa
     6421 cttactttgt tagattcgtt aaataaaaga ataaactttt tagaggaagt tagtagagta
     6481 ctagagttag ataatattac atttatacat ggaagagctg aagattttgg taaagatgaa
     6541 gactataggg aaaaatatga tgttgctacg gcaagagctg ttgctggatt accgattctt
     6601 atggaatttt gtgtaccatt tgtaaaagtt ggagggtatt ttatttgctt aaaaggtccg
     6661 aatgctaatt tagagctaga agaatcacaa aaggctattg atgttttagg attggagtat
     6721 attgaaaaaa tagatgtaga gttaccagag gtagatttaa atcataatat attagttttt
     6781 aaaaaagtga tggaaacacc agttaagtac cctagaaaag ctggtaaacc agccaaaaat
     6841 cctattaagt aatgaaaaat ttattattgg taagcttaat tatttctcag gaaataatta
     6901 agcttactgt aaaaaaacaa aaataaagga attattaaag tagatgcaga aataaatttg
     6961 tatgtacata tagagaacaa aaataattta tatctaaaat aagagaggta tgttatggaa
     7021 gataaaagag ttatggagat acctatagaa gatgtagttc caaatccata tcaaccaaga
     7081 aaaatatttt cacaagtttc attggaggaa ttgagcaatt ctataaaggt atatggtata
     7141 attcaaccta taacagttag agcaaaagat ggcaaatatg aactaattgc aggagaaaga
     7201 agattaagag cagctaaatt agcagagctt aaaaccatac cagcaattat aaataatatg
     7261 aacgatgaat cttctgctgt tctagcgtta ttagaaaatt tgcaacgaga agacttaaat
     7321 ttcattgaag aagcaattgg ttatgaaaac ttaataaaag aacatgcttt tactcaacag
     7381 caattagcag aaaaattggg caaaaatcaa tctactgtag caaataagct tagaatatta
     7441 aagcttccaa acgatataaa aatgaagcta atagagaata atttaacaga aagacatgct
     7501 agagcatttc ttaaactacc aagtgaagat ttaatgcaaa gtgtgttaga caaagtcata
     7561 aaaaatgaat tgactgttaa aaaaacagaa aaattgatac aagatgtatt agaagaaact
     7621 aaagttcaag aagagcctga taaaaaacag aatataaagg gtgctatgag tataagaatt
     7681 tacataaata ctataaagca ggcctttgat gctatatcaa atacaggaat tgatgctaag
     7741 tataatgaaa tagataaggg agattatatg gaagttgttg taaaaatccc taaaaaatag
     7801 agattactgc ttaccagtaa tctttttttg taatataagc cttgtaatat aaattgattt
     7861 atagacatta tttatactta aaaaacacct attcaacatt taaaattaat ttaattctta
     7921 aaggggggaa catcatgggc aaagttatag ctgtattcaa tcaaaagggt ggagtcggga
     7981 aaactacaac aaatgtaaat ttaagtgcta gcttaggaac tttgggaaag aaaatattag
     8041 tattagattt agacccacaa ggaaatacaa ctagtggata tggtattaat aaaaacgaag
     8101 tagaaaatac aatctatgaa attatgttag atgggttaca tattaaagaa gcaataataa
     8161 gtactgaatt tgagaatgta gatgtagttc catcagctac tgaactatca ggtgcagaga
     8221 tagagcttac atctaaaact aatagagagt atattttaaa aaattccata aaagcggtaa
     8281 tagatgaata tgattatata tttttagatt gtccaccctc actggggatg cttacaataa
     8341 attgtttaac tgctgtagat agtgttttaa ttccaataca atgtgaatat tatgctttag
     8401 aaggtgttag tcaattaatg gagactataa aattagtaaa atcaagatta aatgctgata
     8461 tagaaattca aggtgttgtt ttaagtatgt ttgatggaag agctaattta tcaatacaag
     8521 tagttgaaga agttaagaaa tactttaaag gtagtgtata tacaacttta attccaagaa
     8581 atgtaagact tgcagaagct ccaagtcatg gaaaacctgt aatttattat gataaaagat
     8641 gtagagggtc tgtagcttat ttggagctag cagaagaatt tatagattta gaagaggagg
     8701 aatggtagta tggagaataa gtctaaaaga agtaatagat taggtagagg tcttagtgca
     8761 ttgataccag aaattaaagg agaaacttca gaaaaagaaa tagtcaacat agatatagac
     8821 aaaatatatc caaacgaagt tcaacctaga aagcaatttg atgaagaaaa gataaaagta
     8881 ttgtcggatt ctataaaaaa ttatggtgtt ttacagccaa tagtggttaa aatggatgaa
     8941 aataataaat atatgataat agctggagaa agaagattta gagcatcaaa acttgcaaat
     9001 aaaaatcaaa tacctgctat aattaaagat atagatatga aagatataat ggagatagcc
     9061 ttaattgaaa acttacagag ggaagattta aattcaatag aagaggctct agcatataag
     9121 agtttaatag agcattacaa tgtaactcag gaagaaatat cagaagctgt tgggaagagt
     9181 agacctcata taactaatac actaagactt ttaaatcttg gacaagatgt tatagaaatg
     9241 atagacagtg gtagaatcac agcaggccat ggtaaggctt tattgagaat tgcagataaa
     9301 gatttgcaac ttcaaatagc gaaaaaaata gaagaagaag aactttctgt aagagaagtc
     9361 gaaaatatag ctaaaaaaat atctgaaaat aaacaagaag aacctaaaaa atctaaacct
     9421 aaggatgtat ttattttaga tgttgaagat aaacttagaa atatatttgg aacaaaggtg
     9481 aatatttcta aaggaaagaa aaaaggtaaa atagagatag aatactataa tgatgatgat
     9541 ttaaatagta ttgtatcaat gcttcttgaa tagaacaaaa atataaaaca gagaggaaga
     9601 ttgttatgat ttatttagat aatgctgcaa ctacatatcc aaaaccagaa agagtgtata
     9661 atgctgtttt agattgtatg aaaaattatt gtgcaaatcc aggtagagca ggccataaac
     9721 ttgctatgag agctgctagg gagatatatg atacaagaga gaatatagct aagttgttca
     9781 atgtaagtaa tcctatgaat atagtattta catctaatgc aacagattct ttaaatttag
     9841 cgataaaagg tgtattacaa gaaggagacc atgtaataac aacgtctatg gagcataatt
     9901 cagtaataag acctataaaa gcattggaaa aaaggggtat tgaaaatact gtagtaaaat
     9961 gcgattatga gggattttta gattatgaag atttagaaaa atcaataaag agtaatacta
    10021 aactgattgt aacaacacat gcgtctaatg tatgtggaac tttaatagat ataaaaaaag
    10081 ttggagaaat agctaaaaaa cataatatac tatttttagt agatgcatca caaacagcag
    10141 gtgtttatga tatagacgta aatgaatgta atatagatat gttggcaatg ccaggtcata
    10201 aatgcttatt tggacctcaa ggaacaggta tattatatgt aagagaaggg ttgaacttaa
    10261 atatattaaa agaaggtgga acaggtagta aatcagaaga aatagttcaa ccagagttat
    10321 tcccagataa atatgaatca ggaactcata atactccagg tatagcaggt cttaaccaag
    10381 gtatactatt tatatttgaa agaggaatca acaatataag acaacatgaa gaagaattat
    10441 gtcaatatat gatagacaaa ttagaggaag taccagatat aaagatatat ggaccaaagg
    10501 acagtaaaaa aagagcatca gtaatagctc taaatatagg agatatggat tctggagagg
    10561 ttactttctt attagatagt gattataata tagcgactag atcaggaata cattgttcac
    10621 cactagcaca taccacttta ggtactttaa aacaaggtgc agtaaggttt agtataggat
    10681 atttcaacac aaaagatgag atagataaag cagtggaagc tttgaaaaaa atttcaaaaa
    10741 ataaatagca tgagatttaa taatatagaa ataaaaaaag gggatatttc aaaataaaaa
    10801 tttgaatcat ctcctttttt gtacaaaaaa gaaaaggggt tcctaagaac ctctaatcta
    10861 tttgataata gtttcaagaa attactttaa gtaatctcct tcttcaagaa ctatatgacc
    10921 actttcgtaa ttagaaccat caacagtaat ttttatttgt tcaacattca tattttttat
    10981 gtaagtacga gcaactgaat caagcattaa agtttctgca tcactaccta agtttgactt
    11041 tgtaaagtca gagctaacat ctaatatacc agtttttaca ccatcaatgt cttttgtagt
    11101 aaatgaattt aattttgcag attctggaac aactttaagt ttttgaagtt cttcaaataa
    11161 agtgttctca tcaattttat ttaaatcaac tttattttca attaaatctg tcttatctac
    11221 atcaaaagag taaatagtag ctgattgagt tttagtttct tcttttggag taggtttagc
    11281 tttgttatta ggaacctctt tttcagtatt gttttcttct tttggttgct caacatttgt
    11341 attgctctta gtttcttttt tagatgaatc acttccattt tgagcattag tacaaccaac
    11401 tgcgaatata gatatagata atatacttaa cactaacatt attttcttat ttttcataaa
    11461 aatttctcct ctcttaaaaa ctattcttat atataattat agtcgttatg agcaaatata
    11521 tgaatacaaa atagtaacaa atttaaaaaa tgatttattt aaattaataa aactcaaaat
    11581 aaactaaatt ttagtcattt ttatgggaaa tcatttaatg tacagtgaaa atattgtaaa
    11641 ataaaagtag tgtttttaaa ataaatataa gttataatta tattataaaa aaatgtcttc
    11701 aaaaggtggg aatagtatgg aaattttgag cttaggagaa aagattaaaa aattaagaaa
    11761 agaaaaaaac atgacattaa aagaattagc tggagatagg ataacagcag cacaaataag
    11821 ccatatagag agggataaat ctcatactag ttatgaactg ttggaatatc taggcgataa
    11881 gctagatgta agtgtagaat acttattaga gaccaaggaa atgcaatcaa aaaagataac
    11941 tgataattta atactacaga gcgaaattta tataaaagaa aatgaattaa acaaggctga
    12001 ggaccaaata aaagaagttt tagatatatg taagagatac gatttaatgg agaactatgg
    12061 cagatgtaat tttttaatgg ctaatattaa tttgaaaaaa tctaattata atgatgctat
    12121 agaaaacttt gaaaaggcat tgtacttctt tataaaaaat agtgatagtg aaaatatact
    12181 taagtgttat ttaaacatag ggaaaatata tatgcaggaa gacttttata aaggtgctat
    12241 aagccacttt aattttgcag aggaaatttt gtcagagaat aaatttgagg atgttaacat
    12301 acacaaggaa ctatatagta agatggcata ttgttacata aaactagata atccaaatat
    12361 gtcattgaag tacatagaaa agataaatga aatagataat agaaatgata gaaaagaaga
    12421 tgtcgatatt ttggtgttaa aagcaaataa tatgcttgag attggaaaat atgaagaatc
    12481 aagagattac tttaaaaaag cactaaaaat acttgagagt gaggataata aaactggatt
    12541 agcaaatgtg tatttaacaa tttgtgatgt ttacagaaaa ataggtgaaa cagatagagt
    12601 acttgaatat tcacaaaagg tatatgacat aaagaaaaat gatgaagatg aatacatgat
    12661 gtcaggatta tttaagataa tagaagcata tatagataaa gaagattatg atttagctag
    12721 aaaatattgt aagatagcct tagcttcatc aataaaaaat aaaaataaat tcaatgaata
    12781 taaagcattg agattctatg ctaatatgta taaaaatcag aatgaagtaa ctcttgcaat
    12841 tgaatatctg attaaatgca taaaaatagt atcagattta ggcaacaata gaatattggc
    12901 caatttatat atagacttag gtcaattata ttcaaatata tcaaaagaaa aagagttaga
    12961 atattatcaa aaaggtgtat ttatgtacaa aaatttagaa ataatgtagg gtaaataaac
    13021 ctataagggt atagaaacaa tctataacaa gcaagataat atctatgata aaatataaat
    13081 tgtatgaata tttttaagga gatgaatcag acaatgagta taaaaataga tgcgagaggg
    13141 cttgcttgtc ctaaaccagt tataaataca aaaagagaat tggataacct agaagaaggt
    13201 gttgtagtta caatagtcga taatgaaaca gctaaggaga atatattaaa acttgctaaa
    13261 tctttaagtt gtgaagcaaa tattgttgac gaaaaagaga attttatatc tatagaaatt
    13321 agaaaaggta aaaatatact agataaacaa aatgttgtag ataataaaga aagtgaatta
    13381 gacaatacat gtatatttat atcttcagat aagatgggac ttggaaatga cgaattagga
    13441 aaagtgttaa taaaaggatt tatatataca ttaacagaat ctaaacctta tcctaagtat
    13501 gtacttttag ttaatggagg agtaaaatta agtgctgaaa atgaagaaac catagaaaat
    13561 ctaaaaatac ttgagaatat gggtgtagaa gttttatctt gtggtacttg tttagattat
    13621 tataatttaa aagacaaatt acaagtaggt acagttacaa atatgtatac tatagttgag
    13681 acattaaaga atgcatcaaa taccatttct atataatgta tgtttgttta ataatataaa
    13741 attaataata aagattaact caaatagata gtcagaaagg attaagtaat gaatcaaatg
    13801 tatatagtgt catttaattc gacacatcat gcgataagat cagaaaagtt atttggtgaa
    13861 aatagtctaa aagtaatggc tcttccaaca ccaagagaaa taacagcaag ttgtggaata
    13921 tcaattaaat tttcttttga agatatggaa aagataaaaa ctattttagt tgaaaataat
    13981 gtagatataa aaggaattta ttgtataagt aaattagaaa atggctcaaa agaagtagag
    14041 aagttagatt aggaggctaa ttatttatgc caatggattt aaaaataggt gatattgttg
    14101 aattaaaaaa gcaacatgca tgtgggtgta aagagtttga aatcataaga acgggaatgg
    14161 atataaagat aaaatgtact aaatgttcaa ggctaataat gcttgataga gagaccttag
    14221 aaaagagagt aaaaaagcta ataaaaaagt gataaaaatt taacacttaa aaaatgtcaa
    14281 ataccgtata ttaatatcca aaattttggt ataataagaa ttgaagaaaa cattttcatg
    14341 ggggtgcttt aattatggca gttaaatatg caaaaagaat gcaaggatta caaggatcag
    14401 aaatacgtga gcttttaaaa cttactcaac aaccacaaat aatatctttt gctggtggaa
    14461 tgccggctcc agagttattt ccagttgagg aaatgaaaaa agtatcagtt gcagtgcttg
    14521 aagaaaatgg aagatcagct atgcaatata ctacaacaga aggatatgaa ccattaagag
    14581 aaaaaatagc agctagaatg aatgataaaa acaaaactaa tgtaaacaaa gatgatatat
    14641 tagttacaag tggttctcaa caaggtctag attttgcagg aaaagtattt attgatgagg
    14701 gtgatgtaat tttatgtgaa agtccatctt acataggagc tataaacgca tttaaatctt
    14761 atcaacctaa attcatagat gttccaacag attctgatgg aatgataatg gaagaattag
    14821 aaaagatact agaaacaact gatagaataa aaatgattta tgtaatacct gacttccaaa
    14881 atccaacagg aagaacttgg ccacttgaaa gacgtaaaaa attcatggaa atagtaaata
    14941 aatttgaaat accagtaata gaagataatc catatggaga tttaagattt gaaggagaga
    15001 ctttaccatc tttaaaatca atggatacaa aaggattagt aatattctta ggaactttct
    15061 ctaaaatatt ctgcccagga tacagattag gatggacttg tgcttctcca gaaattttat
    15121 ctaagtttaa ctttgcaaaa caaggtgcag acttacaagc atcaactata tctcaaatgg
    15181 aagtaagcaa atttatggat atgtatgacc tagatgcaca tgttgacaaa ataaaagcag
    15241 tttatgttaa acgtagagat gtaatgctta agactatgga agaagagttc ccagaaggat
    15301 tagtatttac tcatccagaa ggtggattat ttacatgggt agagcttcca agtaatttaa
    15361 atgctaaaga attaatgcca aaatgtttag ataagaatgt tgcttatgtt gctggaggag
    15421 gattcttccc taatggtggt agagaaaata ctttcagact taactattca aatatgccag
    15481 aagaaaaaat aatagaaggt ataaaaaata tagcagctgt attaaaagaa gctatgggtg
    15541 tagaagctta attaaaaata ataacttata tataatacaa gggatggttg ttgccatccc
    15601 ttgtttgttt gaaaagtata taattcacct tatactaaac tttgtccaaa atttaaattg
    15661 acagaaataa gaataaatga taaaatgtgt aggtatgaga ttttagtctc atttctctgc
    15721 tctaagagtg tagagccgtt aagtccaaag ggaggtgaat tatagtgaga aattatgaat
    15781 tagtttatgt ggtaaagcca aactctgatg aagaagtaag agaggctata ctaaacaaag
    15841 ttaaggaagt tgttgcaact gacggagaaa tagttaaagt tgatacttgg ggaactaaaa
    15901 aattagctta tccaatagct aagtttacag aaggtttcta tgtattagtt aacttcaaat
    15961 cagcagtaga cgttcctaaa gagatagaca gaaacttaaa gataaatgaa aacgtaataa
    16021 gacacatgat agttgttgct taataactgg ttttattata aaaaataggt ggtgttttta
    16081 tgaatcaagt tgtattagtg ggaaggttga ctagagaccc tgaattaaga tacatcccag
    16141 gtacaggaac accagtggca tcctttacaa tagccattga tagagactat gtaaaaaaag
    16201 atggatctaa agaaactgat tttatacctg ttgaagtaat gggtaaatct gctgaatttt
    16261 gtgctaacta cataactaaa ggtagattag tagcacttca aggatctata agagtagaca
    16321 attatcagac acaatcaggt gaaaagagaa cttttacaaa agtaagtact agatcagtac
    16381 aagctttgga tagtaagaat aaatcggaaa attcatatag agagagtgct ccagcttttg
    16441 agccaagctt tgaacctcaa ggtttagacc cacaaggttt ccaagctata gatgatgacg
    16501 atataccatt ttaaaaagga gggaaaaaag tcatgatgaa taaaaaaaga cgtaagaaaa
    16561 aaagagtttg tcaattttgt gctgacaaaa acgctaaaat agattacaaa agtactcaaa
    16621 gattacaaaa gtatataact gaaagaggaa agatattacc aagaagaata tctggaactt
    16681 gtgctaagca tcaaagagaa ttaacagttg ctataaaaag agcgagaaat atagcacttt
    16741 taccatatac attagactaa aaaaatgagc cttgtgctca ttttttatta tatgtattta
    16801 tatatctaaa tgaggcgagc tataaagctc gtttttttgt ttatatactt aaatatatta
    16861 ttatttatga tataatatta tatattaagg agggttgtaa acgtgaaaat agataaaggt
    16921 tctgagataa cgagaaacat aaagataata gaatggatga aaacagaaat attaatgagt
    16981 gtaagtgatt tgtttaattt attgtttaaa ggggtaaaac cattagatga agcaattcaa
    17041 gatactttag caaatataat aatgataaca tatctcttag caaagagatt aggaattagt
    17101 tttagagatg tggattataa agtcaaggaa aaaataaaaa ttggtataga tgaggaccat
    17161 agcgttgaaa gatggtatgg agatttatct aatttaaaaa aacatatgga taatagggag
    17221 tgatattaaa ttgaataata aaattagact atctaaggca atgtctataa tagttttagc
    17281 tataataatc gctttagtaa tagcctatat tccaatgcta ggaatattta gtatgttagc
    17341 agctgttcca tatgtaatta taggtgctat tactgataga aagtattctc ttatatctat
    17401 tttggttaca ttttgtgtac tgattctatt tgcagacatt tcttatgcat taaatatatg
    17461 tataatgtat tctttaccag gtatagtaat aggaaagatg ctaaagagaa gctttgaaca
    17521 agaggacagt aataaattcg aaccgatata tggtggaacc ataatatttg tactttcaat
    17581 gcttgtatat ttttttgtat taaagacatt tttaaatgtg aatctattag atgaagtttc
    17641 taagatgata tcagaaattg taaatattca aaaaaatagt ttttctgcaa ctgaacttaa
    17701 agtgtttgat aaaatgaagc cagatgagat tgtaagttat tttacaaata tgctaccaat
    17761 gatgttattt ttacaagggt tgttatcagc gtttgtcaca tattatttga gtgtattttt
    17821 tataaaaagg attacaaaga tgaatataag atttcctaag tttgctgatt tttatttacc
    17881 gggaaatgct atactcacaa ctttcttact ttatttatta gtcttattta ttcaaattat
    17941 tggttcaaaa ttatatacag aattaataat gactaattta cagctagttt ttaatttaat
    18001 gtttgtaatt caaggtatag cagtttgcat ttatttctta aagaaatgga taagacaggg
    18061 accaaataaa attatgtttt tttcagggat aattttatgt ttatttggat ttatgggaat
    18121 atcttttgtt ggtatggtag atagtataat tgactttaga aaggtaagaa gctataaatc
    18181 cacttaggag gatagaaatg agtaataaac aaacctttaa attaaatatg ccagaaataa
    18241 atttatatat aattgttatt ggtatttcta gtataatttt gctttattac aacttgtatg
    18301 tagggtgttt atttttctgt atttttgtat atatggtttt tcacaattgg agaactacta
    18361 atattagacg tcatgaatgg acagagtata ttcaaaattt atctttagat atagatgaaa
    18421 caactaaaaa agccataata aatcttccaa taccattatg tattttagaa tttgatggaa
    18481 atatatcctg gtataatgga aagttttatg atatgattgg tcaaaaagat ttacttgata
    18541 aaaatataga ggatatagtt aaaaatctta atttaagaaa agtattaaat gaaaataaag
    18601 agatgtacac agaaataaac tataaagaaa aagaatatac aataatttat aatgttataa
    18661 aaaatgatca agaaaaaaat cctaaatatt tgatgatatt atactggata gacaagactg
    18721 aatatttaaa agtaaaacaa aattatgatg atgaaaaaaa tgcaatgatg ctaatacaag
    18781 tagatggata tgatgaagta ttaaaaagtg cagcagaaga taagagagct ttaattaatg
    18841 ttgaagtaga gaaaatactt tctgctttag aattaaattc aaatggtgca ttgagaagaa
    18901 cttcaaaaga caaattcttc ttggtaatgc ataaaaaaga gttaaaaaaa ttggaagctg
    18961 agaagttttc tattttagat acaataagac atattgatta tggaaataat cttcctgtta
    19021 ctataagtat aggaattggt atagatggag atacattaaa tgagaaccta aaacttgcta
    19081 cgggtgctct cgatttagca cttggtagag gtggtgacca ggctgttgta aaaacaaaag
    19141 ataaatttgt gttttatgga ggaaaatcta aagctgtaga aaagaaaacc aaagtaaaat
    19201 ccagattaat aggtcatgct ttaagagagg ttatacaaca aagtgaccaa gtttatataa
    19261 tgggacataa atatcctgat atggatgcta tgggagcagc agttggtgtt tatgatatat
    19321 gtaaatcctg taacaaaact gcaaacatag ttttacaatc tgtaaatgaa tctatagaaa
    19381 tatttataaa taaaataaat gaaaataatt actataaaaa gttgtttatt ggaaaagagg
    19441 aagctattga caactgcact aaaaatacat tagttgtagt agttgatact catagaccaa
    19501 attatactga atgtgaagaa ctgttaaagc tatcagagaa ggtagtagtt atagaccatc
    19561 atagaagagg tgtagagttt ataaatgatg cagtgctttt attccatgag atatatgtat
    19621 cctcaacgtg tgaaatggtt acagagttag ttcagtatat ggatgaagat gtaacaataa
    19681 ataaacttac agctgaaggg cttttagcag gtataagtct agatactaaa aactttgcat
    19741 tcaaaacagg tgttagaact tttgaagctg cttcttacct tagaaaagtt ggagcagata
    19801 ctatagaggt aaagaaattc ttcaattctg atgtaaaaga tttcataata aaagctgaaa
    19861 taattcaaag tactaaaata attaataata gaatatgttt agcatattca agtactgaga
    19921 tagatagtat aaatgttata atagctcaaa ctgctgatga gttattaaat atcaaagaag
    19981 tagaagcttc ctttgtatta ggtgaaaaag atgatactat atttataagt gcgaggtctt
    20041 taggacaaat aaatgtacat gtacttatgg aaaaattagg aggcggggga cacatagata
    20101 tagctggagc acagttaaaa aatgtttctc taaaagaagc ttataagatg gtaaataaaa
    20161 taatagagga gtatttggag gaggaagaat agatgaaagt tatattatta aaagacgtaa
    20221 aaggaactgg taaaaaggga gaaatgaaag aagtaagtga tggatatgca agaaatttct
    20281 tatttcctaa aaagatggct gtgcaagcag atagtgtagc aataaaagaa ttaaatgaaa
    20341 agaataaatc taaagaaata aaagcacaaa aagagtatga agaagcagtt ttattaggta
    20401 agcaaatgga agaaattaat atagaaatat attcaaaagc aggagaaggt ggaagattat
    20461 ttggttcaat aacttctaaa gaaattgctg agcaattaaa gaaacaaaaa gacatagatg
    20521 tagataaaag aaaaatatta ttagatgaac caataagatc tttaggttca actttcgtag
    20581 aaataaaaat acatcaaaaa gtaactacta aaataagagt ggatgtaaaa gaaaaacagt
    20641 aataactaga ggtgattaag atggaagata tgacgagaat tcctcctcat agtgtagaat
    20701 cagaacaatc aatattgggt tctatacttc tagataaaga tgctataata acggttacag
    20761 aaactataaa gcctgatgat ttctataaag aggctcacaa aataatatat gaatgtatga
    20821 taactttaag taataaaggt gagcctatag acttgataac attaacagaa gaactaagaa
    20881 aacaagggca tcttaatgat attggaggaa tcagttatat tacaagtctt tctactatag
    20941 taccgacgac ttcaaatgta aaatactatg ctgatatagt aaaagaaaag tctgtactta
    21001 gaaagcttat aaaagcttct aatgaaataa taaatctagg atatagtgga gcaactaaga
    21061 ttgaagatgt tttagaacaa gctgaaaaga gtatatttga tatatcacag gagaaaacta
    21121 gtgatgattt taaatctata aacttagttt tgatggatgc ctatgatatg atagaaaaat
    21181 tatacactaa caagagtgat gtcactggta taactactgg ttttaaagat ttaaacaaaa
    21241 aaataaatgg tcttcaaagg actgatttaa tattaattgc agctagacca gcaatgggta
    21301 aaactgcctt ttctttaaac ttggttcaaa atgcagcctt aaaaggtgat gcctctgtag
    21361 ctgtatttag tttagagatg tctaaggaac aattagtaca acgtatgtta tcttcacaat
    21421 ctagtgtaga attaaaaaaa ataaagactg gaacacttaa tgataatgat tggcctagaa
    21481 ttatagatgc tatggcagta ttatcagatg ccaaaataca catagatgat actcctggta
    21541 taaaaatatc agaactaagg tcaaagtgta gaaagttaaa aatagaaaaa ggactagatt
    21601 tagtgcttat tgattatctt caacttatgg aaggtgaagg taataatgaa agcagacaac
    21661 aagagatatc taagatatca aggtcactaa aaatattagc aaaagaatta aactgtcctg
    21721 tagtagcact atctcagtta tcacgtgcac cagaacaaag agcagaccat agacctatgt
    21781 tatctgattt aagagagtct ggagcaatag aacaggatgc agatatagtt atgttcttat
    21841 acagggacga atattatcat gctgattctg agagtaaaaa tataggagaa gtaataatag
    21901 caaaaaatag acacggtgaa actggttctg tggaacttgt ttggcttggt gaagttcaaa
    21961 gatttgggga taagttgaga gacctataat ctaacgaata tccacagaac gtcctttctt
    22021 tctacaggaa aaatgtggat acatgtcact aaatatgtcc aaacattgaa atttagctaa
    22081 aaaactatcc acactatcca cagatggcct gttgataagt gtgaataagt agataaagca
    22141 agcttttggc ttgctttatc tgtgtataaa tattaattat taggaggaat aatatggaaa
    22201 aaataagctt aaaatatata tatcccaata taattaaagt acttgatgaa ataaacttat
    22261 ttagagtaat tgacaataat ttaagagaat ctattgttgt ttatgctaat aatgtggata
    22321 atcagtatca tataaacatg actaatacaa actttggaaa tataattaac atatgtaaat
    22381 tagaaaaact tttagatgtg gataaattta tggaaaaagt tataaaatat gaaaaagaaa
    22441 taatagagaa agaagagttt tcaaaaatag aagaatatat gttaaatatt ggagaatact
    22501 aaaaaagttg aaaaaaatac gaatgtttga tagaataagt aagtaaagtg ttcgagagta
    22561 tataaaatat agaggtgaat tacatgaaaa cagttgcaat tgttggttct caatggggag
    22621 atgaaggtaa aggtaaagtt atagattatc ttgctactca agcagatgta gtagtaagag
    22681 ggcaaggtgg aaataatgca ggacatacat tagttgtaga aggtaaaaaa tacgcattac
    22741 atctaattcc atctggagtt ttaaatccaa atacagtgaa tataatcgga aatggaatag
    22801 tgtttgaccc taaaggattt ttagaagaat tggaaatgtt taaaacggat aatataagta
    22861 cagaaaatat aaaaataagt gatagagcac atgtcatatt cccatatcat aaagaactag
    22921 atgcattgtc agaagaagcc agaggcgatt taaagatagg tacaacaaaa aaaggtattg
    22981 gaccttgtta tatggataaa acagagagat ctggtattag aatatgtgac ttaatggata
    23041 aagataaatt tgctataaaa ttaaaagctc aaatagatgc taaaaatgaa atagttaaaa
    23101 atatatatgg aaaagaagaa ttatttgatt ttgaaactat atataacgaa tatctaggat
    23161 atgcagagca aataagaaaa tatgtggcag atacgtctgt tattgtatat gatgcagtaa
    23221 gagcaggtaa aaaagtattg tttgaaggag cacaagggac tttattagat ttagatttag
    23281 gaacttatcc atttgttaca tcttctcatc caacatctgg tggatttgca attggtgcag
    23341 gtatagggcc aaatatgata aaagacgttg ttggtatagt aaaagcatat actacaagag
    23401 ttggagaagg accgtttgtt acagagcaaa taaatgaaac tggagataag ataagagaac
    23461 aaggacatga atttggggta actactggta gaccaagaag atgtgggtgg tttgatgcag
    23521 ttatagttaa gtatgcagct agagttaatg gattgactag tatttcattt atgttacttg
    23581 atgtattaac tggatttgat aagataaaag tttgtacgtc ttataaaatg ggcgataaga
    23641 taataacgga tttcccagct tcattagatg atttagcaaa atgtgaacct gtatatgaag
    23701 aattagatgg atggaatgaa gatataactc aaatagataa ctttgatgac cttccagaaa
    23761 atgcaaagaa atatgtagca aaaatagaag aactagttgg agtaagtgta gatatggttt
    23821 ctgttggtcc aaatagagct caaactataa taagaagaaa tatatttgct taatatttta
    23881 tcaattaaat aatttaaaat agttgaagaa gagtatctca agataatgtt tatagttatt
    23941 agagatgctc ttttatattt gacttacatt gattttttat taagttaaag ctacttatac
    24001 atattctaac tgaaattaaa gttgaattta tgtagataca tataggtttt ttaaaaagaa
    24061 ttttgttgaa aataaatggc taaagatgat tttaattata ttctaaaaaa agtaaaaaaa
    24121 actattgact aaaaattata tagacgctat aatataactt gtgagtgaaa gaaacgacga
    24181 aaaaagtcga aaaaatgtgg tctattagct cagtcggtag agcacctgac ttttaatcag
    24241 ggtgtcccgc gttcgagtcg cggatagatc accaaaatat ggctcgttgg tcaagaggtt
    24301 aagacaccgc cctttcacgg cggtaacagg ggttcaattc ccctacgagt caccagtatg
    24361 ggactatagc tcagctggga gagcacctgc cttacaagca gggggtcaca ggttcgagcc
    24421 ctgttagtcc caccaaattt tgaattagag ataaatacta gattatatgc tggtgtggct
    24481 caacggtaga gcagctgact tgtaatcagc aggttgtagg ttcgattcct atcaccagct
    24541 ccacaaagta cataaattca aattaatata attttctatg ttacaggata cttttaagta
    24601 tcttttttta atttcatttt tattgtatta aaaatgaaat taaacataca acaaaatttt
    24661 gaattacttg caatgtgata gttttaaata taaaatttag aatcattcta gcataatatt
    24721 atgtaatata gcaaatttaa tttatagtat caataaatat agactactaa gaatgtaaat
    24781 gatttgttag attaaggtac attagatatg taaatagaaa aataaaaagt atgttttaat
    24841 ttatgtgata taagttttaa acagagaagc aagtttgctc ttacctctct atttaaaaat
    24901 aaaaaaatgt tttttaaggg ctattttatt taaatctttc ccatctcaaa tcatctccag
    24961 taaattctaa aatcctaaac ttatctaata ttctagagag agttctttga gtgtaagtat
    25021 ttcctatttg agatggtgtt aagttggttg aaataatgat ttttttacca gcaacaagtc
    25081 ttgtatttac aatattgaag atttctccac tagtaaaaga attattaagt tcagttccaa
    25141 ggtcatctat tattaataaa tcacaatcaa acaagttttt ataattatct tcacttattt
    25201 gattatttgt gtctcttcta aatttataat cttcaagaat atctaaaatt ctaaaagaag
    25261 tttgatagat tacaacattg cctttatcta acaattcctt tgcaatacaa ttgcacatat
    25321 aggtctttcc tagtccagta gaaccataaa acagtagatt ttcactatta tccttcttaa
    25381 aatcatgaac aaaattttcg cagatactta aattatttag catattttct ctaggagata
    25441 tttcaccatc agagcctttc ttaggagaaa atatattcaa gttaaaattc gaaaaatttt
    25501 cctgacttaa aatcctatct aaattagaca ttttataagc ttcatttaca atttcttgtt
    25561 tgaggcaaga acatttttct ccattaggta aaaatccttt atctttacaa gaaatacatt
    25621 gaaactttat ttccaagtaa tcaagaggta tgttactttc agctaaaagt ctttctttct
    25681 ttacttttaa agattctata ttctctttag tcttctttac aatttcatct ttagacttag
    25741 gatttaaaag tactatctta gctaaactga gacctatttt agaaatttca tcatctatag
    25801 attttatctc agggattcta ttatatacct cattttttct atgttctaat aagagttcat
    25861 tatcatctct tctcttagca tatttagcaa gtatttttct tattttatcc tcattcattt
    25921 aatcacctac ttaaactttt ctttttgact ttttttaata atctcatcga gctcatcaga
    25981 ggtatactga gtgaatgttt cgttgaaatt atgaaactta gtttttttgt aagtattgtt
    26041 gttttgagta gtattaatct gcttcttatt aatattctcc ttaactatac gttcttcctc
    26101 tttttgcttt aaatcattta aattttttat atttttttca ttccaatttt taattatacc
    26161 atttatataa gatatacttg ggtttgaaat attcttagac ttagaacatg catttattat
    26221 caaatctata tccatattaa atttatcaaa ccaggtgtcc ataagttctt tttctgattt
    26281 tgatggttgt cttgaaaatc ccaattcatt gaaaatcgtt ttatataaaa tatatcgttc
    26341 acttcttacc aaaaagcttt cttcaacatc ttttggcgta tataaatttg aatcatacca
    26401 atttctaata atgccttcaa tgtatttaac tggctttgat gtaccagttt tatctttgac
    26461 gtattcatat gcgcaaagta tcatatcggg gctcatattg tatttattca ttatatccat
    26521 aatactcatc ttttcacttg ggtcgagata tcgcccaact attttattta tagaattaaa
    26581 catttttcta atacttggat tttcagaagt agatacaact ttatctgtat tagattttat
    26641 agatgaatta ttgcttaata tattctcaat atagaaattt tttaaatcta aaaattctat
    26701 tgaataatta aaattatcat attcttcatt gtcatgtatt tttataatct tcttttcttc
    26761 ccagaatttc caagcagata acacatcaga caatggtata tttaggtttt tggctattga
    26821 attattgtcg aacttaggat tagaagtaat atcacatgct tgtctatatc ctaaaagata
    26881 aacttttacg tataacccgt ccgccattgg cataaatata tctataaaga tattgggaat
    26941 agtgatttca cctaaatcta tttcattgct ttctttaaaa aacattttat cacctcagat
    27001 taaattatat cattttttat attatatttg tctgtaaaca aataaaaggt cacaagatta
    27061 gcatgtaaat attttctaaa agtattcatt ttgaaaagga ggagatattt tggttataaa
    27121 attcaaccaa aaagtaagaa gaacattatc agtagcgatt ctatttatgg tattaataat
    27181 aggttgcttt atagaaaagg atgacagttt agaaacatac aaagaaaaaa ctaattcaaa
    27241 aataaatcag tataatatgg atgttatatt tgatgatgag actaagaggt taatgtgcaa
    27301 tcagaatgtt gactacataa ataatacaaa atcaaacata gataaaatat atttccatat
    27361 atatccgaat gctttttcca agaaagattt tgctcctttt gaaaaaagtg aaatgacaag
    27421 ggcttatcct aatggattta acgaaggata tatagatata aagaatatat taaataataa
    27481 tagtaaaatg gagtataaaa ttaaaggaga caaaaatgac atattagaaa tagaattagg
    27541 gaaagagtta aaaccaaatg aaagaatgtc attagatata aaatataacg taaaaatacc
    27601 aaattcaatt ggaagatttg gatatggaga aaatactata aatgttacta attggtttcc
    27661 tatagcttgt gtaaatgatg aaaggggatg gaatttaaag agttatgaaa ctattggcga
    27721 cccattttat agtgagacta gcgattttca tgtgaaacta ttgattccaa ataaatataa
    27781 aattgctcat acaggaaaac ttattgatga taaacatgat aataagaaaa tgctatatga
    27841 aatagaagct gaaaacgtta gagattttgc atttatacta agtagtaaat ttgatgtaaa
    27901 caaagtagat tcaaagggag tagctatcaa tacatataat ttaaataaaa agctttctaa
    27961 aaaagcaact gaagtggcaa aagattcaat aaatatattt agtgaattat ttggaaagta
    28021 tccttacaaa gaattttctg ttgtagcaag tgactttttt atagggggga tggaataccc
    28081 tatgcttgtt atgatagacc aaagtttata taatgaaaaa aatgaatttt tactagaata
    28141 tgttattgcc catgagacag cacatcaatg gtggtattct gctgttggaa atgatgaaat
    28201 aagtgaaccc tggttagatg aagcacttac tgaatattct acaatagttt attttgaaca
    28261 aaagtatggt aaagatatgg caaacaagct tataaaaact atggagatac agacaaaaag
    28321 ttatttgagt gaaaatatat ttaagccagc aaatgagtat aaaaattcta ctgaatacag
    28381 cttgaatgtt tatacaaaag gcgcaatagc atttaatgaa ataagaaaag aagttggaga
    28441 taaagtattc tttgagactt taaatgagta ctataataaa tataagcata aaaatgctaa
    28501 tggaagagct tttgtggaac tatggaatag taaaggtgta gatataaata agattataag
    28561 tgaatgtaag taaatagtga atgtaagtaa attttgtgca gagtattaaa ttttatttaa
    28621 tactctgttt ttttggtata atataattta taaggcagaa aaagaggtga aggaatgcta
    28681 aagtattgtt cagtagggag tggtagtagt ggtaattgcc actatatagg gtataaaaat
    28741 actaatatac tagtagatgc aggattaagt ggcaagagaa taactacagg tcttaaagac
    28801 attggtgtag atgcagataa attaaaagga atatttataa cacatgagca tgttgaccat
    28861 ataaaaggag caggtatatt atcaagaaag tttgatatac cagtatttgc taatataaaa
    28921 acatggtgtt ctatgaagga caaattaggt gacatcaaag ataaaaatat gaaagtattt
    28981 gaaaatgata aaacctactc attaggtgat atcatagtaa gacctttttc aatagaacat
    29041 gatgcgtctg acccagttgg atataatttt tatacagaga gtgatgaaaa aatgtctata
    29101 gctactgata taggatgtat aactcaaaat ataaaaaaac atctatataa atctaaatta
    29161 gtagtattgg aatcaaatta tgaccctaat atgcttatga tgggttcata tacatatgct
    29221 ttaaagaaaa gagtaatgtc aagtactggt catttatcca atgaagatgc agctaatttc
    29281 tgcgttgaac ttattaatga aggtacagaa tctatattat tagcacattt aagcaaagaa
    29341 aataattttc ctgagttagc gtatgagact tcaaaaggag tattagcatc aaatgatata
    29401 gtagttggac aagatgtaaa actagatgta ctatcacgaa atgatgtttc taatgtttat
    29461 gagatgaagt agaggtgaat aactttgcta aagagaaatt ttgaaaatgt tgaggataat
    29521 aaaattttat actctataaa gcagggtatg attttagcga tacctgctat tatgactggt
    29581 tcaactgctc ttgtaatttt gaatcttcca ataaaggctt atcaagaata tttatcaggc
    29641 ttgtttaatg gagaggttac aaatattctt aactttataa atgattctac tttaggaatt
    29701 atttcattaa taatattatt aacaataagc tatagttatg gaaaaatata tgggagcaag
    29761 tatacagtac ttgttcctat agttgcaatg tgctcttttt tagtattttc acatggtaat
    29821 gagcttaatt cttatataga aatatttaaa acaaagtggt tatttacatc tataattgtt
    29881 tctatgacat cttctgtatt gtttgtaaaa cttacagaat cttttgttac aagtgtaaag
    29941 tttcatacag aaggggctga tgcagacttt aatatggtag tttcggctat agttcctttc
    30001 ataatagtag tatttttgtt ttctattttt agagtggtaa tgataagtct aattggcagt
    30061 tcaaactttc aagatatatt ttataattta ttttcaaatg tttttaataa aatgggaaca
    30121 aaccttatga gtgctctgtt gtttattttt ttaatgcact ttatgtggtt ttttgggatt
    30181 catggtagta atgtattaga taccgtcgca aaaaatttat ttgaaaatag tatggcaatt
    30241 aacataaatt tagttaataa taatcaatta ccaacagaaa tttttactaa gacctttttt
    30301 gatacaatgg ttttattggg aggatgtggc tctttactat gtttagtaat tgcaattttt
    30361 cttagtgaaa aacgtataaa tgtaagaaag ttagctaaaa ttgcttcaat accagctctt
    30421 tttaatatca atgagatgct agttttcggg ataccaattg tttttaacta tattatgttt
    30481 gtaccttttg taattactcc tataatctta accgttacaa gttatgtggc tatgtctaca
    30541 ggtattgtac catgtacagt ttcagctgta gaatggacct cacctatatt tttaagtgga
    30601 tatatgtcta caggttcaat aagaggtagt ttgttgcaag tatttaattt atgtgttggt
    30661 gttatgattt atattccgtt tataaaaatg tcgcaaaata gatatacata tatgtttaaa
    30721 aataatatag aaaatttaac aaacttatta aaaaggtatg aattaacagg tgaacagcct
    30781 aatcttctaa accataatgg taaaataggt tcaatttcaa aaatgttggc atcagacttg
    30841 aagtttgcta tgaaaagagg agaaatagag cttttttatc aaccacaagt caattataat
    30901 ggaaatgttg tgggagcaga gggattactt agatggaaac attcaatagg agggttcatt
    30961 tatccaccac tagttataat tttggctaaa gaagaagggt tcttagatga gcttggagag
    31021 tatattatta ataaagcatg tattgattta aagaagagtg aaaagctatt gagaaatcct
    31081 gttaagttct ctgtaaatat atctccagac caacttgatg accctaagtt accagagcaa
    31141 ataaaaaata tcattagtag taatgatata aatcctaata tgttaggtat agaaataaca
    31201 gagcaaattg cattatcagg ttcacaaata attattgaac gtatcaatgc gatacataac
    31261 ttgggaataa agttaattat ggatgatttt gggatggggc atagctctct tatatatctt
    31321 caaaataata actttgatat agttaaattg gatggttcat tagttaaaga gatacttaca
    31381 aataaaagaa gtagtgaaat tataatgact attgtaaatc tttcaaaaaa tttagatttt
    31441 gatatagttg ttgagtatgt tgaaaatata gaccaaaggg ataagttata tggtttagga
    31501 tgtgaaatat atcaaggata ttattatagc aaagcaatac cttttgaaga gtttgtagaa
    31561 tatgcaaatc aagaaagaga gatataattt tataagagct tgtaaattct agtaatgcat
    31621 agatttgtaa taaaattaag tttaggagaa atatatgaat ataagtatag tagtagtagg
    31681 taaaattaaa gaaaaatatt taaaattagg tattgatgag tttaagaaaa ggctttctaa
    31741 gtattgtaag ttagaaatta tagagttgga tgatgaaaaa gctccagaga atttgagtgt
    31801 taaggaaatg gaaattataa aagacaaaga aggaaagaaa attttaggga agataaagca
    31861 taatagttat gttatagcct tggctattga tggtaagggt ttatcctctg aagagcttgc
    31921 taagactatg agtgatttag cagttagagg taatagtagt ctctgtttta taataggagg
    31981 ttctttaggg ctttctgatg aggttttagg aagggctgat tataggttat ccttttctaa
    32041 gatgactttt cctcatcaga tgatgagatt gatattgtta gaacagattt atagggctta
    32101 taggataaat aatggagaac cgtatcataa ataaatgata cggtttttgt taatttgaca
    32161 cttaataata ttaaaataac aaaaaagtat tgaaagtata ttgcatttaa ggtagaatta
    32221 aataaaatat tataacatta taatgtttat atggttgtta ataaaaattt ggaggaaaat
    32281 atatgataaa aataatgttg gcctgttcag caggaatgtc tacaagttta ttagttacta
    32341 aaatggaaag tgcagctaaa gaaaatggta tagagtcgca aatttgggca ataccagaat
    32401 caactataca aaatgaaata gaaaaatgtg atgtattatt actaggacca caagttagat
    32461 atgtattacc taaggctcaa gaaattgcta agccatataa tataccagta gaagttataa
    32521 atatgatgca ctatggaaca gttaatggag aagctgtttt aaatagagcg atagaactta
    32581 acaacactaa gtaatataaa ttataatgta tttttaatat ataaattggg agaatcaaag
    32641 gatggatgaa aagactatag aaatatcttt taatataata ggttatgcag gtgaaggtaa
    32701 aggattagct tttgaagcaa taaaagaggc taagaatgga aatatagaaa aagcaaaaga
    32761 attattaaaa gagtctaggg aagttataaa taaagcacat agatatcaaa cagaattaat
    32821 acaaaacgaa gctagtggaa acaggactga aataagtgtc atacttatac atgcacagga
    32881 ccacttaatg aatggcatga attttcaaca gttagctgag gaaatcgttg atttacattt
    32941 gaaattacaa gataaataaa aattaaagat aataaattaa gagagttctt aaaagataca
    33001 ttatgtgtag cacactaatt gttagattat tgattcaata tttagtgagt aatacattag
    33061 gattattttg aggactcttt ttatatttag tttaaagtta ataaatattt attattaata
    33121 atataagatt atatgttata atattataac atataattta agaggtgaat catgttaaga
    33181 aatcaaccat tatatataca agttgtagat atattaaagc aaaaaatatt aaataacgaa
    33241 tataaaattg atgaaaatat tccaacagaa agggagttag agcaagagtt tggagtcagt
    33301 aaaattacta ttagaaaagc tattgagata ttagaatcag aaggatatgt agagaaaaaa
    33361 agtggaaaag ggacaaaagt aataagtaat agccttttta ataagctatc aaaagcagag
    33421 tctttttcaa gtatactttt atctaaaggt cataagttat ctaaagagac tatttcaatt
    33481 gaaaaaataa taaatgatac aaattcacaa gtatttagta tatttggaga aaaatgtagc
    33541 aagattacta gaatgtatta tttagatagt aagccatata tattttttac tcattatatt
    33601 ccttttgatg aaaatctaac tgttgaaagt tttaataatg aaagttcttt atatatgtac
    33661 ttatatagga gaaatataaa tataactaga tttgaagatg aattttttat agaagaatca
    33721 gaactagagg tatcaaaggc tttaaatcta gctaaagaca tattattagg aagaaaaaga
    33781 aagacctatg atgagaatga taatatagtt gagctatcat ttgcaagata taatacagaa
    33841 gtacaaaact atgtaattaa atacgaaata taataagaat cctgagttta ttgaaatgat
    33901 aatatgctca ggatttttgt ttagttgtaa aaataaaaaa tattataaca ttataatgtt
    33961 tacaaccaaa cattataatg ttataatatt tttaataaac aagtgatatt atcaattaca
    34021 taaaaattag tttatgttat gaaatcgtta ttgcattata aataaaggat aatatcaata
    34081 atacaggggg ataactatgg aaaaattcgc aagtttttta gagcgcaaga ttatgcctgt
    34141 agcagcgaag ataagtaatc agagacatat gagagctgta agagcaggta taatagcaac
    34201 attaccacta acaatagtgg ggtcattttt cacaatatta ttaaacatac ctattgatgc
    34261 ttatatggat tttatagctc catttaaagc aatattagat ataccattta gatatactgt
    34321 aggattttta tctctatatg ctacttttgg gatagcatca tcacttgcta aaagctacga
    34381 tttagataca acaggtgttg gtatgcttgc agttatggca tttttagttt ctacaatagt
    34441 tccaactcaa gtagttgaac cagtaggtgg agttatagaa gctggtagat ggatggatat
    34501 ggcaaaactt aattcgccat cattatttgg agctatcgta acatcattaa ttacagttga
    34561 aatatatcgt tttatgaagg aaaagaatat tacaattaag atgccagcag gagttccagt
    34621 agaggtttca aattcattta ctgcattatt accgacagca gtaattttaa tgttattctg
    34681 ggtaataaga catattctag gatttgatat aagtgttgca ctaagcgcta tgttatcacc
    34741 tttaaaagga ttcttatcag gaaatagttt aggtggtggg ttactgacag tattcctaat
    34801 aactttattc tgggtacttg gaatacatgg ttcagctata atgggaccag taataagacc
    34861 tatatgggac atgtctatag cagaaaatat aactgcattc acagaaggag tatcagctca
    34921 tgcaatgcca aacatattta cagaacaatt tttacagtgg tatgtatgga tagggggagc
    34981 aggggctact cttgcattag ttgtaatgtt tatgttttct aagtcacaat atctaaaaag
    35041 tttaggtaga ttaggatttt taccagggtt attcaacata aatgaaccta taatatttgg
    35101 agcaccaata gttatgaatc caatactagg gataccattt ataattggac ctataataat
    35161 gacaattcta tcatatgttc ttactattac aggggttata cctatgatgg tagcaagatt
    35221 accatttgca atgccagcac caatagcagc agtaatgagt actaactgga gtatactagc
    35281 aggtatctta gtattaatca actttgtgat atcatttgct gtttattatc cattcttcaa
    35341 agtttttgaa aaacaacaat tacaaagaga acaagaagaa atgagtgaaa atttataaaa
    35401 atacatagat atagaggttt tgtactatat aaaatataga aaaagcttat aagttattaa
    35461 gggtgaaggt aggaggaatg acctttgcct ttaattttat atattttaaa taatgtaatt
    35521 tgaggaggag aaagatggaa agaagattag gaatatcagt atatccagag catagtaaca
    35581 tggaagatga taaggcatat ataaaaatgg cttcaaaata cggatttaaa agaatattta
    35641 tgtgcatgct ttcaattaca agacctaagg aagaagttaa aaaacatttt aaagagatta
    35701 taacctatgc aagagaatta ggatttgaag taatccttga tatagctcca aacatatttg
    35761 atatattaca aatatcttat gatgatttaa cattttttag tgagttaaat gctagtggaa
    35821 taaggcttga ctatggatat gatggaagta aagaagctat gatttctttc aatccatatg
    35881 atttaaaagt ggaactaaat atgagtaatg atgtagcata cttggataat ataattactt
    35941 acaagccaaa tgtaaataat atatatggtt gtcacaattt ttatcctcaa aggggtacag
    36001 gcttgccata tgattttttt gtaagatgtt caaatagatt taaaaagtat ggaataagaa
    36061 ctgctgcttt tgttaattca aaatacgcaa caatagggcc ttggaatata aatgatgggc
    36121 tgtgtacgct tgaaatgcat agaaacttag atattgctac agcaaccaag cacttattcg
    36181 caacaggatt gattgatgat gtaattgtag ggaatgcata tgcaagtgaa gatgaattaa
    36241 aaagaatgtc tgaagtaaat aaatatcaag ttgtatttaa tgtagtaact gaagaaaaaa
    36301 cttctgaagt agaaaagaca ataatggcaa atgagcaaca ctttagaaga ggggatataa
    36361 ccaaccaagt agcaaggtct acagaagtaa gaaaaaaata tgctaaagaa aatttcccta
    36421 agcatgataa tacgaccatc tttaaaagag gagatgtagt gattggtaat gatgactttg
    36481 gaaagtataa aggggaatta cagttgatac ttcaagattg tgcagatgaa agaaaaaata
    36541 aggtgggtag aataaaggaa gacgaaataa tacttttaga ctttattgaa ccttggagta
    36601 aatttaaact tattttagag ggagagtaaa gtgaagatag acatattaat aaaatgtgga
    36661 aaaacagtag ataaaagtat aattgatata gctatattag acgataaaat aatagaagta
    36721 aaaaatcaga tagatgattc taagtatcag gcaaatcaaa ttataaacct agatggagaa
    36781 aaatttatta gtgctggttg gatagatata catacgcact gctacgaaag actagacctt
    36841 tataaggatt atccagatga ggttggaata aaaagcggtg ttactactgt agtagatgca
    36901 ggaacaacag gagctttaga tataggtaaa ttttatgaag atactaaaaa atataaaaca
    36961 aatgtatatg ctttaataaa tattgctaag cagggaataa catctcaaga tgaactttca
    37021 agtatgatga atattgatga atatgaactt agaagagcag ttaaaaaata caaagatttt
    37081 gttgttggaa tcaaagctag aatgagtaaa agtgttgtaa tttcaaatga tgttgaacct
    37141 ttaaaagtag ctaaaagaat aaaaaatgaa cttaatctac ctatgatggt tcactttggg
    37201 agttctcctc caacgataga ggatatattt gactatatgg aaaaaggaga tatattaacc
    37261 catatatata atggaaagcc aaatggaata cttagaggca atgaggttaa aaaagaaatc
    37321 atagaagcta gagaaagagg tataatcctt gatgtaggtc atggaaccga aagttttagt
    37381 atggatattg caatgaaatc taaggatgca ggaatttttc cagacactat aagtacagat
    37441 atatatatta aaaatagaat aaatggtcca gtgtataatc tatctacaac aatggaaaag
    37501 tttatatata tgggctattc acttgaagat ataatagata aagttactaa aaatgcagca
    37561 gatgcaataa gtttaaaaaa taaaggttta ataaaagaag gatatgatgc tgatttaact
    37621 atatttgatg tggttaatga agaaaaagaa cttcaagatt ctttgaataa gtcagtaatc
    37681 acaagtacgt ctataaagcc aagagcagta gtagtcaatg gagaatattt aaatataggt
    37741 aagtctatag gagagaatga gtagaaggga gaaactattg tatgagtagt atatttgaaa
    37801 aatactctgt aagacgtgtt ataaatgctt caggcaaaat gactatacta ggagtatcaa
    37861 cagtagataa ggaagttatt gaagcaatag gtgaagggtg taaaaatttc tttataatag
    37921 aagaacttat aaataaaaca ggtgaatata tagcaaattt attagggtgt gaaagtgcac
    37981 taatagtttc tagtgcatct gctgggattg cacagagtgt gggagcaatg atagcaaaag
    38041 atgatatgag tctagtttac aatgtaaata atcctaagaa acaagttaaa agggaaataa
    38101 taattccaaa gggacataat gttgattatg gagttccagt agaagtaatg ataagacttg
    38161 gaggaggaga agttgttgag gccggttatg ctaatatgtg taacaaggaa catataataa
    38221 gagagataaa tgaaaataca gcagcaatta tgtatattaa atctcatcat tgtgttcaaa
    38281 agagtatgct aagtgtatta gatgcagtac aagttgctaa agaatataat ttacctttga
    38341 tagtagatgc agcagcagaa gaagatttaa atgtatatta tgaattggga gcagacctag
    38401 tgatatacag tggtgctaag gctatagagg gtcctagctc agggttagta ataggtaaga
    38461 aaaaatacat agataatgta aagcttcaat caaagggtat aggaagagct atgaaaatag
    38521 gaaaagaaaa tattgtaggt ctaacatgtg caattgagag atatataagt aatgataaag
    38581 taactttaaa agaaatggag gataagctaa atccatttat agacaagata aatactataa
    38641 agggagtgag tgctagtata actagggatt cagcaggtag agaaatactt cgtggagaaa
    38701 ttgactttaa tgaagatata ataaataagt caacacaaca aattataaat gaacttagaa
    38761 gtggagagat agctatatac actagagact ataaggctaa tgaaggcaag attgagattg
    38821 atataagaag tgtaactgga agtgatttag atactattta taataggata aaaaatatag
    38881 tagaaagtta gagtgtagag taagtgacat tataatgatt taataaatta aattttacca
    38941 atggagggga taaatatgaa ttgtatacca caatattata aaaatagagt ttgtttaaat
    39001 gttcttgcag gaagcataaa aaatgctaaa gaagtatatg atgcttgtga cgggcatgta
    39061 ttgataggaa tactatcaaa gaattatagc actgtagaag cagctattga agatatgaaa
    39121 aaatactcaa aggaaataga taatgcaata tctgtggggc ttggagctgg agacccaaat
    39181 cagtcaaata tggtatctca gatttctaaa gaacttcagc cacaacatat aaatcaagtg
    39241 tttacaggtg tggctacgtc tagagcattg cttggtcaaa atgatagtat aataaatgga
    39301 ttagtttctc caactggtaa accaggattt gtaaaaatat ccacaggtcc attaagttca
    39361 aaagaaaaag atggtatagt tcctatagaa acagcaatag ctatgatgaa agatatggga
    39421 ggaagctcaa ttaagttttt tccaatggga gggcttaaaa caaaggatga atatatagaa
    39481 gttgcaaaag cttgtgcaaa gcataatttt tatttagaac caacaggggg tatagactta
    39541 gataacttca aagagatagt tcaaattgca cttgatgctg gtgtagaaaa agttatacct
    39601 catgtttata catcaataat tgataaagaa acaggtgaaa cgaaagtgga agatatagga
    39661 gtactttata aaataatgaa agaattattg ggatagattt atgaatatat tagcttttgg
    39721 tgaaataatg atgagacttt cagtacctga ctacaagttc ttaacacaaa ccaatgaact
    39781 aaattatata actacaggca cgggattaaa tatattatct ggacttaaaa actttggata
    39841 caatacctat atgttgacaa agttgcctaa taataatgta ggtaaagcat caagtgcaaa
    39901 tataagaaag cttggagtaa aagatgactt tatcacgtat ggagggaatc atataggagt
    39961 gtattttctt gaaaatgggt atggagaaag accttctgaa gtgacttatt tgaataggtt
    40021 aaatagttca ttttgtgaga gtaaattaca agattatgat attgataaat gtttagaaga
    40081 aatggatata gtccatattt gtggtattgc tatgcaactt acagattcag ttaaagagat
    40141 tgctttagaa ctagctagaa aatcttatga aaaggggata aaagtattct ttgattttaa
    40201 ttttagacaa tcattaaatc cagaaaggac ttatgatgat ttagtaaatg attataagaa
    40261 aatactacca tattgtcatg ggctgtttgc tagttataga gatataaata agatacttaa
    40321 tatagatagt ctaaatataa aatctagttc agaattgatt aaaaaagagt atgatataga
    40381 tattgtagct ggaactatga gaagatttga tgatatgaat aatagattta taaagggata
    40441 tatatcaaat gatgatggtt attttgaaag tagggagtat aagctagaaa tatatgacag
    40501 ggttggtgcc ggagatggat atgtagcagg aattatatat tcatatttgg aaaatatgaa
    40561 gagtgaagat atagttgagt ttggggttgc tagttcggtg ttagctcata caacttatgg
    40621 ggataattct ttagtaagca caggtcatgt acttagactg atgaataatg aaaaaataga
    40681 tatattgaga taatacattt gtatataata aaatttttat cttttttaga cacatttttg
    40741 acttgcttat atttgttaaa cagagttatt tttaatgatt ataaatatta aattaaaagt
    40801 taaataataa aatagtagaa aatagcatta actatagaaa aaatggttaa tgctattttt
    40861 atcgttaata ttgattaatt ttatattata gaaatgaact tttctaatgc tggatttgta
    40921 ttttttttat tccatacaac tacaacttca attctatttt ctacttcttt tataggtact
    40981 attgcaatat cacgttctat cattgtatct gtaacacaaa atgaaggtaa aatggatatt
    41041 cccatgttag aagataccaa tgattcaata gtattaagat tatttgaacg ttgtaccaca
    41101 ttaggtacaa accctgcttc acgatatcta ttctgtatca ttgacttttg tccatactca
    41161 tcccctgttt cctttacaaa aataaattta tcatgttgta attcaattaa atcgatagaa
    41221 tcctcattgt aaagtggatg accaggaggt aaaagagcta ccaaagaata tctttctaca
    41281 gttttatatt caaaatcttt taatggttga ttttctggat taataacaaa agcgaggtcc
    41341 atagaattat tttttactaa gtttaaaagt tcggttattt cattagtaca aatatccata
    41401 gatatattag ggtatgtatt agaaaattct tttaaatatt gttgaagttt gtttttttca
    41461 tatcctatta aggttccaat gctcaaagtt ccaaaaaaac catgtgcaaa ttgttgtgtt
    41521 tttgcaatag catcattgat attttttatt atagtacgtg cctcagataa aaaaactttt
    41581 ccagctggtg ttagttcaac atgacgttta cttcttgtaa atagagttac atttatttgt
    41641 tcttctaaag cttttatttg ctgtgtaaca gcagtttgag aaatataaaa tttttctgct
    41701 gttttggtaa aacttagatt ttctgctaca gatataaaat attctaattg tttagtattc
    41761 aaataatcac ccctatttaa acttgattgt ttgtaaacct tatttatcta taattaaagc
    41821 ttattatagt ataagaaaat ttacttttaa agaatattag aaaatatttg tataaaaata
    41881 tatgttttaa gtatatcttt acattagatt ttataaattt attaataaga ataacttata
    41941 tattccaatg aaaacgatat tggatttaag taagtttgtc tcataaaatg aaagtatatc
    42001 aattgataat actttaaata agaagggaga aaaaatggaa gataaatttt atgcaaaagg
    42061 caacggaaat aacggatata ttaaaaatct tgaagtttgt tcctttaata acttagatgg
    42121 aacttgtgga atgtttcaaa tggctctgta caaaagagat gaaaaatact atttatatgg
    42181 atgctgtttt ggaggaaata aaaaaaatgg agtaatgatt agcgatatta cagaccctta
    42241 taatccacaa tttataaaac attttcaaat gttagaccct aaagagtatc ctacaacaac
    42301 aactcccaaa attcaaatag cagatgattt aatgatagta gcaatgagtt gtggaagtgg
    42361 accaggagca cttgttgacc aagctaaatt agcaaatatt aagtgtgaag caggaattag
    42421 aatatatagt ttaaaagaag accctttaaa tcctaagttt ttaggatatt gggattgtgg
    42481 cttaaagcat gtaatgggtg ttcatagatt catgtacaat ggtggaagat atgtacattt
    42541 atcaagtgat tgtgttggct ttgaaggtct gatttatagg gtcatagata taataaatcc
    42601 tactaatcca gtggaaatag gtaaatggtg gagaccagac caatatgcaa atggatatcc
    42661 aaatagaact tttgatgcag gagcacctca ttgcccagaa tttatggata aaggatggct
    42721 tcatggacct ccatttgtaa gagacggaaa agcatattgt ggttatggag gagctggttt
    42781 agttgtatta gatgttgaag atttaacaag accaagatgc ttaggtgaat tgccatttat
    42841 gcctgcattt tctagtagac ttgcaggtgc aagaactcat acagcattac cattgccagg
    42901 aagagattta gtcgttgttc aaaatgaggg agaaagattc cagttcttta aaccagataa
    42961 cattacagat gttcaagcta tgaataatat acatatggtt gatgttagtg acccaacaaa
    43021 accaacatta attgctcaat ttccatatcc tgaagttcca aaagatttcc cttatcctaa
    43081 ctttaatgtt gcgggattag gaaaaccagg gccatttggc ccacataatc ttcatgaacc
    43141 aatggataat aagccatggt tagagcaaag aggagataga gtatattgct gttatttcca
    43201 tgcagggcta agggtttatg atgtatcaga cccatattat atcaaagagc tagcatattt
    43261 tataccacca aatccaaata aaacaccaga agaatcttat ttcccaggat tcccaggacc
    43321 acgcttggca gtaacagaag atcttatcgt tgatgataga ggctacatca tcatagatgc
    43381 tttagatgat ggattctata tattaaaaat gaaagaagat taaataaata ctaaagaggg
    43441 agagttgaaa atgaaaatac taggtatttc ttttggaaca aaaaatggaa ataatgacac
    43501 aatgtgtaaa gttgcactta aaggtgccaa agaagcaggg gctgaagtag aatttattca
    43561 aatgtcatct attaacatta aacattgtac tggatgttgt gcgtgtgtta aaactttatt
    43621 atctgggaaa ggtagtatgt gtgtattaaa agatgatttt gaatggttgc ttgacaaaat
    43681 gaaagatgca gatggtatag tagtttcaga ccctattttt gaagaagggg catcaggatt
    43741 attccatact ataatggacc gttttggacc cagagcagat agaggaaata acattatagg
    43801 aacaaaagtt gcagaagcta taggaggaaa aattccagat tcaagaatgc ttaatgataa
    43861 agtaatatca tttatgggaa taggaggttc tgactggggt acaagagttc aatgtgaaca
    43921 tgctatgcta gctctcatac caatgtggaa agttatagat aatgcttggt tcccatgggc
    43981 aaaggaatta gtaatggatg atacaaggct tgttcaagtt catcaaattg gtttaaatat
    44041 agttgaagca gcaaaagatt ttgaaaaagc ttcatatcaa ggagaagaag gtgtatgtcc
    44101 acattgccac aatagattat tctaccttga gccaggtact aaaaaggcaa tttgtgctct
    44161 atgtggtata gttggagagt tagatactat aagtggaaaa actatattta gttttccaga
    44221 agagcaatta ggtcatgctc atgatacttt accaggtaag tttatacatg gtgatgatat
    44281 taagaaaatg gaaggtcatt atgcagaagt tcgtaaaaca caagaattta aagaaagaaa
    44341 aacatcttat aattttatag agccattaac taaagaaaag caagctggag tttcattagg
    44401 ataataatta aaatactaag actctttttt aaggtatgtt agatgttata ggaggcttat
    44461 tgtatgaatg aaaagtcaag ttttaaacaa attgaaatta ttttagcagt tatttttttg
    44521 gtacttacat attacaaggt tagattaact ccagcattta ttgttatatt tataccacta
    44581 tatttaagtt attttgcagt atctatgatt gtaaatcaaa tagcaattaa gctattggag
    44641 ataaggcaag ctagggaagc tactaattac aatataggaa atggatagaa agaaaaaaga
    44701 aatattaaca ctgtctatgg ggattgcttt actacctcct ttatgggcag tattagcacc
    44761 ttatatagga ataaaaactg gagctgtagc actaatctgt gcaggattat atgtaactaa
    44821 tggtaataaa caaaaagatg gattaaaaat aatgtttggt ttttggtgtg gagatttatg
    44881 ggcagtgtta gccattttaa ttatgggata tatgaatttc aatcaaaacc tagaattatt
    44941 tttaacactt agtatattag gtttttttgc agttgtaatt gcatccttat ttgaaaaaat
    45001 aattttccta ccatcatggc tttgtggttg ggctataggt ctaactatta tgacaggtga
    45061 aaatattatt aatttacaag atatttgtat tcaaattgct gtagctatgg cagtaggagt
    45121 atggtacgtg ggtgcaggtg tagatttgtt tacaatatat attttgagta aagataggaa
    45181 aaagggaaat tgaaagcatg tgaatatact ttgattatag gagaatggct atgggttttg
    45241 aatttaaaat aatgagaagt ttaatatatg taggacttgc caaggaagaa tatagaccta
    45301 agctaatgga ctggttatat cgtcaccata ttccagatag tattagcact tttggaccat
    45361 attgtactaa atatgccttt tatcaagcat atcctacacc aaatgaaggt gagcgttttg
    45421 gtgcacgtaa gatgcaacta acagaacatt attggcttgt agatgaacat atgcctgaga
    45481 tggcaaatag aattatgaca gaatatatgc ctatggatgt tctacgttgg caagggtgta
    45541 taccagatgt agaaaataaa agggttcatg aaaatgcaga aagtggagat gcaggacgtg
    45601 cagtaggtgg agataatgga tgtccaccat ttatatttgc ctttgttcca ataaactggg
    45661 aagaagactt tagaggaaaa ggacgtactg tacaagatgg accaaactat cgttggcaat
    45721 ttatgattaa gtatccagat ggtatctcta aagaagaagg agaaaaatgg ttctatgatg
    45781 aggtagtgcc atactttaca aactgttgct atgttaatcg ttttgtcagt agtaaaataa
    45841 tgattaatta tggagcaact gcttttgacc gtgtatcaga actatggttt gaaggggaag
    45901 aagaatggta taaagctgtg gttgaagaga caaagtcgtt tattaaaaaa ccagaatggg
    45961 cacaagaaga ggagttccca tatttaaaac cacaattcaa tatcgcatca gtattcttag
    46021 gtgatatagc aactatggat gcatactcac agtatcgtgg atatatacca atgagataaa
    46081 aattatagtt tgtgataagt agaggaggca tttactctta ctggtagaag aagacttatt
    46141 gtatccttaa aagtaggtga atatatagtt ttatatttaa atttatataa aactaagact
    46201 aataaatatg aaacaataga attagaataa tttgataata tttgttaaaa gagcatttag
    46261 aatgtgttta aagattaaga tattcctttt atggtagcag atagttgaaa taataaaact
    46321 gttatcatga aaggaatatt tttatgtata ggaaattttt aaaaataaaa gttaaatatg
    46381 tttaagaaca tcttaaagtg aaagaatcat tgttagaaat atgtagacaa tatagtcttt
    46441 ataacgtatc atattaacaa gtttacactt ggattatgaa ataaaaagag taattccaaa
    46501 ggttgtaaat actatgctga ctttgatact tcaaagttta ggtgattttg taattgttaa
    46561 tagaaatacg tttaatgagc ataaagaatt tatctaataa taggagaata taatgtatac
    46621 aattggacaa gtatctaaat ttttaggaat atctagagat acactaaaat tttatgagga
    46681 caaaggatta gtaaatccta agaaaaatga tgaaaatgga tatagaatat ataatcaggt
    46741 tgatatctat gatattgcaa caataaactt ttatagagaa attgatatag aaattaaaaa
    46801 gattcaagaa ataagaaaaa gtaagagtat aaacaattta gaactcttac tagaagagaa
    46861 ggaacaaatc atactaaaag agatagaata taaaaagctt ctcttaaaaa aggttcagtt
    46921 agtcaaagaa gattgtgaca aaataaaaac atattttgga aaatacacaa taaaagaaat
    46981 gaagcctttg gaagtaaaag gtaaaataaa acatgttact aactatgagg aatatgaagc
    47041 cttaaaagag aatacaaaca acttaaaaaa agcagttaca ttaactgatt taagaagagt
    47101 aataaatttt aatgaagaag gtataataga agaaaaattt ataattgtaa gggaagtaga
    47161 tgactacaac aaaatcatag aaggtgaagt tctatctcat cccaattgta tttatactat
    47221 tattgaagat ggcagatggt caactggagg agaaaatatt gataataaag tggaagacag
    47281 attaagagaa atagcaatag aaaatgaatg tgaattactt ggaatagtct atgttaatat
    47341 attgcttact acttatgaag aagggattga gcgtatattt ttagagattt atgcacctat
    47401 aaaataatat aaaagcattg acctgggact tactcatagg tttaaactca tgatataagc
    47461 agttataact tatatagcaa ttaaatatta atttgaaatg aggattactt atgagaacag
    47521 agaaatcatt aaaaaggcct atagccagtt ttattattct aacaaatata atttttttac
    47581 cacttttttt attggtagta gtgactataa tgttaaaact tccaacagtg atatctgaca
    47641 ttgcgttgtg tatatcagcg tggtcatcca cttttgcatt tatgatatta tttaaaaaaa
    47701 tttatccagg taagaaattt ttagtacacg taaaagatag atttagaaat aaacttaaat
    47761 tttcaacagt atctataata attagtatac aagtcctaat agctgtagta gttatattta
    47821 tattagcatc taaaaatcat ggaataatgc ctaactttac agtttcatca tggggagcat
    47881 ttatatattt atttttaaaa aatttatttg caggatcatt aggtgaggaa ttaggttgga
    47941 gaggatttgt tcaaaatcat cttcagaaaa gacattctcc tttaaaagca tccataatag
    48001 taggtttttg gtgggggatg tggcatttac caatatggtt tacaacagga ttcaaaggac
    48061 ttgatttaat aaaatatatt atatttttta tgattgcaat tatatcaatc agtattataa
    48121 tgacaacttt ttataatcta aataaaactt tgataatacc tattgtaata catcaactat
    48181 ttaatttttt aatagggata attaatggag atttaataga gcttataaat tactatgcaa
    48241 tgttatattt aatatttgca attgcattaa tagttataaa tccaggaaat gtattatata
    48301 aaaatattag agagtaatat atatctttat ggtaagatat aaagatatta ttagaagaac
    48361 atccaaggag gaataaacat ggttttactg attgttgatg cacaaaagtt aataacaaac
    48421 gagaggttat ataaatttaa tgaatttgta gtaaatgtag aaaatttaat tgatacagct
    48481 agaaaaaata atatagaagt aatatatgta cgtcatgatg atggagttga aaatgaattg
    48541 actaaaggta aaaatggctt tgaaatatac gaaaaattta aaccatgtaa tggagaaaaa
    48601 atatttgata aaaaagtaaa tagtgctttt aaagaaactg gtctattaga atacctaaca
    48661 aataatggtg aaaaagatat tattattgct ggtctccaaa cagattattg tattgatgcc
    48721 actataaaat gtggatttga acatggattt aatataatag ttccagctta ttcaaataca
    48781 actgttgaca atttttttat gtcagcagaa caatcatata aatactacaa tgaatttata
    48841 tggaatgaaa gatatgcgaa gtgtatttca ttagaggaaa cacttagaaa aatgaaataa
    48901 aaatagagta tgaattgtat atgtacataa gttgatttca taaaaaagga tgttaaattc
    48961 caagttaaaa attagattaa atatattata ttatagataa ggcacatcaa ttttatttta
    49021 aattaatgtg ctttttaatt gtagtaattt atttataatc aatatgattt ttattattta
    49081 aatcaatttt tcttgagttt ctttgtctaa agaaactttt tttatttata aaatctacag
    49141 ttatattata gtatctattt tagagaagtt taatttttgt atcaatctaa aacaaaagtt
    49201 atacttaaat gaaattgaaa acgataaaat tctcaaataa aataagtatt gtggaggtga
    49261 tgaaagaatc caatgataat atgaagacta atcttaataa gaaagtaggg gttaatggta
    49321 gtggacaaag aaattgtatc aattctccag attttattaa atagcacatt gattacaact
    49381 aatggattac aagaggagtc taattcatca aagagacaaa ttacttatag aataaataaa
    49441 atcaatgaca tgcttaaagt aaaaaatgta ccacttatat gtttaagagc tgataaagat
    49501 attatcgtta gaaaagaaac aaaaaaagca attaaagaaa ttttagaaaa aaactattct
    49561 aagaatactt attattttag taagacagaa agacttttat atatgtattt aatgcttttt
    49621 attaacatgg atgatatttc aattaatcat tttataaatt ctataaaagt aagtaggtct
    49681 actgtaaatc ttgatttcaa ggatttgata ccagagcttg aaaagaagaa cattaaagtt
    49741 aagaacaatc gtataaatgg atattacata gttggcaatg agatggaaat taggagagtg
    49801 cttattaaaa atattataga aactttgtct aatgagaaaa gttcaagagt atttgatatt
    49861 tttattaaag aatataattt agatagtttt gaagaggcta aaaaaattat attaaagcta
    49921 ataaaaaaat atgaaattac ttttgttgaa gatagattag tagaatttat atatatattt
    49981 atctttctaa aggcaaggat gtattcaact agaatagtta ctcaggaaaa tgtagatatt
    50041 cctaatattt cagttatgag ttcaatgaag gagtataaat ttgctaagga attattagaa
    50101 gtatatggga gtgaagataa gataaagcct cacaatataa tgtatattag tgcttggatt
    50161 ttaggtatat cagtaggaaa ttatgaagaa gatacagaag ataaggatgt aatttcaaaa
    50221 attgtaaata aaatgatgac aaagtttgga tatttaagcg gagtttacta tataagccaa
    50281 gaaaaaatat ttaaacaatt atattctcat tttagacctg cctactatag acttttattt
    50341 aaattaccta tttataatcc gatttgtgaa aaagtaaaag aagaatataa attagtttat
    50401 agaattgtaa gtaatgcaat gaaagagttt tgcggattat ttggagaaga aattcaggaa
    50461 gaagagttag catatcttac aatgcacttt gcaacacttt tttcaaataa aaaagaattt
    50521 gatggtttta gaaaaagaat agcattaata gtttgttcaa atggcgttgg tagttcagct
    50581 attttacatg cagaacttac aaacttattt cctgacttac actttatacc aatgtcggaa
    50641 tcagttggat tagaaaatat aagtgaacct gtagatattg tatttactac taattataac
    50701 gcagagggtt taaaaacaga tgtaccagta attaaagtaa gccctgttat gaccacaaaa
    50761 gaaaaatata agattacacg tgaagtgtat attcaattag gtgatatttt tttaagacaa
    50821 cctaaaatag atgaggttat ggatataata aaaaaatatg caaatgtaac ctctgaaagt
    50881 attctttcaa gtgagctatt agcttatttt acacagatag agaattttac atctaaggaa
    50941 ggagaggggc ctatgctaag tgagattact aatgaaacac tagtaaaaat aaaggtaaaa
    51001 gctaagaatt gggaggaagc tattagacag tcagcttctg tattagttga aaataacaaa
    51061 gtaactgaag ggtatgtaga tgctatgatt aactcagcaa aagcatctgg accatacata
    51121 gtaattacaa aacatgttgc acttccacat gctagaccag aagctgggtc aaaagagatt
    51181 gcaataggca ttgctacttt agatagtcct attgagtttg ggaataacga aaacgaccct
    51241 gtaaaatatg tattttgtct aagtgcaata gacaataata gccatttacg tgctatgtct
    51301 gagctagttg aactattgga agaagatgag ttttttaagg ttttagatag tgctaaagaa
    51361 gctaaagaaa ttattgattt tataaaaaca cacgaattat aaaggaggat ttaattatgt
    51421 ataaaatttt aatcgcatgt agagcaggag ttggctcaag tttaatgtta aaaataaaga
    51481 ctcaacaaat tattaaggaa aataactttc caattgaagt agaacatggt tcattggatt
    51541 cactaaatgg attcaatgga gatgctgtag aaacattaat tgatgttgct gaagaattaa
    51601 aaaataaaaa tttgaagttt gatataattg ggattcacaa tattgttgac cgtaatgaaa
    51661 taaagacagc actagaaaaa ttccttgctt caaaagaggg ataaatttaa gatgataagg
    51721 aggaatattt atggagttta ttattagttt gctgagtaca cctgctgttt tgcttggcgt
    51781 agttgcatgt ataggattga ttcttcaaaa gaaatcagct gttgaagtat ttacaggctc
    51841 ttcaaaaaca cttatcggtt ttttgatatt tggtattggt gcctctgcta tgacaggagc
    51901 acttcaaaat ttcaataaac tgttccaaca tggctttgga attactggtg ttatagcttc
    51961 accagaagca gctacagcac ttgcacaagg tacatatggt tttgcagttt catgtacatt
    52021 aattcttgga ttcatattaa atttagtatt tgcacgtatt acaaagttta agaatatttt
    52081 ctttacaaca ggtcatagtt tgttcttttc ttgtgtatta gttttaatta tgaaagcaca
    52141 tggatttgat aatacaatca ctattttaat aggtggaact atcttagggt ttatgtctgc
    52201 tgcactacct caattctgtc aaccatttat gcgtgaatta acaggtggcg acgaacaagc
    52261 tattggtcac tttaacatga ttggttatgg tttatcaggt tatattgggc gtttattttc
    52321 aaaacataaa gatgatacaa cagagactat agaatttcct aagtggttat caatattcag
    52381 agacttctta atgggtctat ccatagttat gttaatctta ttttatattg caacattaaa
    52441 agctggtcaa gcatttactc aagaaattgc tggttcaaca cattggttgg tttttccgct
    52501 tatagaggca tttacatttg tggcaggtat gtcaatattg atgtcaggag ttcgtatgtt
    52561 cttagctgaa ataactgcag catttgtaat catttcagaa aagtatattc caggttcacg
    52621 tcctgcgcta gatgttccaa ccgtatttcc atatgcacca aatgcagtta ttattgggtt
    52681 tatatcagca tatgctgctg gtctattagc aattgctatt atggcatcat ttcctagtat
    52741 atttcctgta gtaattattc cagctgctca catatgtttc ttctcaggag gtacagctgc
    52801 aatatttggc aatacttcag gaggatggag aggggctatt gctgggtcat ttgttgtggg
    52861 gttattactt gcatttttac cagttatact atatccagtt tatgggactc ttggtataga
    52921 aggagcaact ttccctaata ttgattacaa cgtagttggt tcgatattac ataatatttt
    52981 acaatttata aaacctattt agactaaatt atataaaagt atagtcatag ttactatgat
    53041 ttcaaggagg atacatctta tggaaaatac attatctgaa tttttagata atatatctaa
    53101 tgaattgtca gaatttattg cctcaataga tgagacatct ataaataaag catgcgaatt
    53161 aattcttgaa gctgaaaaaa atcacggacg tgtacatgtg actggtattg gcaaaccagg
    53221 acatgtatcg ggatatattt catcattgct ttcatctact ggaacgtcag catatatatt
    53281 gcatggtaca gaagcagtac atgggtcaag tggtcaagta gttgaaggag atgttgttat
    53341 tgcaatatca aatagtggtg aaactcaaga gttaaaagca actcttaaga ctctaaaagt
    53401 aaatggagca aagataattg gtgtaagtgg taatgagagt tcatttttaa aaaatatttc
    53461 tgatatattc ctgtttgcag gtgttaagca ggaaggagat tgtctcaata aagctcctcg
    53521 tgcttcaatt ttagctgaaa caataatatt acaatcatta agtgttgtat tacaatatgc
    53581 taaaggtctt aatacacagg agtatttgaa gtggcatcca gcaggaagtc ttggaaagtc
    53641 tattagagag ggaatataat tttatgaaat ataaagggat tatatgtgca atgataacac
    53701 catttgatga aaatcaaaat attaattcac aagcaacatg tcaattaatt gattatttga
    53761 ttgaaaaggg aatttatgga ttatttattt tgggcactaa tggtgaatgt catgtattaa
    53821 cagatgatga aaaagttgaa tttgcaaaga ttgttattaa tcatacaaat aatcgtgtac
    53881 ctgtttttgt tggaacaggg ggtaattcaa ctcgtgaagt tgtagattta tctaagagaa
    53941 tggaagcgat tggagcaagt gcattatcta ttattacacc atactttgtt acaccaacac
    54001 aacaggaatt aatcttacat tacaaaacta ttgctaattc agttaattta cctattataa
    54061 tgtataatat gccaggtaag actggaatta atattgaacc agagtcagta cgtgaattat
    54121 caaagataaa gaatattgtt ggaattaagg atagtagtgg taaacttgac aacatgaaag
    54181 cttatattga agcaacgaag aatgagaatt ttagtgtgtt ttcaggctca gattcactta
    54241 ttctggatag tctaaaagct ggtagccaag gagctgttgc agcaacaaca aacttcctca
    54301 cagagattgg tatctctatc tatgaaaact ttatgaaagg ggatttggaa gaagctcaaa
    54361 aatctcaaag tagtatagaa gaacttcgac gtatactgaa acttggaaca attccatctg
    54421 ttatgaagaa aactattgtc ttgaatggaa ttaatgttgg aactgcacga cttcctgtaa
    54481 ctgaaccaac tggggaagta cttgaagaaa ttaaacgagt agttgaaaat tataggacaa
    54541 tacttaataa aagtagtgag aatagataat ataaataggg aaattacact ggtatataat
    54601 taatatatat attataaaac atgactaaaa ttaatgaata agtaaagtgg tttgatgagt
    54661 atagaggtga taatatgaaa aagatgaata taaccaaaag aatgtcagaa tgtggggctc
    54721 ttgcaattgt aagagaagaa aatcttaacc gtgcatgtga aattgctgaa ggatgtataa
    54781 aaggtggtat aacagttata gaaatgagtt ataccctaaa taatgctgga gaaataattc
    54841 aagggcttaa taaaaagtat ggtgaaatac tttgtgtggg agcaggaaca gttttggata
    54901 gtgaaacagc tcgtcatgct atattacatg gagcccaatt tattattgca ccaaattata
    54961 atgaaggtgt agcgaagatt tgcaatagat atcagattcc ttatgctcca ggatgtacat
    55021 cattgactga ggcagtagac gcactaagtt taggagcaac ttttataaaa gctttcccaa
    55081 tatcagattt ctatggacct aaactagtaa aggtatttaa gacaccaata cctgatatgc
    55141 cagttttagc aagtggaggg cttaatattg aaaacctaca tatatggtta gaaaatggag
    55201 ttgatgtatg tggatttggt ggtttattaa ctaaaggttc tgttgaagat attgctaaaa
    55261 atgctaacaa gattcgtgaa atcattaaaa atgtaagaaa aatttaacat agggctgtat
    55321 catagtatct tataattact atgatacagc ctttttaata ttattcaaat ttaaaacagt
    55381 ttacatttct attatattac atataatttc agtaatttta tcttaatttt tctatctgga
    55441 aaaaaatgat ttaaaactta agttatgata taatttcatt aaaagaaggc gatttttagt
    55501 aaatatgaga aaataatgtg tttttagggg aaaagttaaa tacagattta agtgaacaag
    55561 aatcgataat taagatatta aatggtgaat agggcatcaa aaaaattact aaattaaaag
    55621 ttttagaggg agaatcttag caagtgtgtg tgaaaattca atttcaaaca aaaataattg
    55681 taaatgaaat caatttatac acgttgaaga ttcactttta tcattatatt aaaaagcaga
    55741 gtgaattaaa agtgagtcta aagataggag gataattaaa acaatgaaag aagacattag
    55801 gttacatcga atgtgtaaaa aagaacaagc aacaaagaat gaagttatat cagaggatat
    55861 tctaaaatct atgagtattg gggtcagtaa acatttttta gatgattcat ttacaataat
    55921 atggggaaat acatcattct atcaattatt aggatataca gaagaagaat ttttagttaa
    55981 attttctagt ttaaaagatt attatgaaca gaatctttat cattttgaat ctatgaaaaa
    56041 tcatttttta gaggcttatc atcatggcga aaagagtata gaatatcaaa tttgcatttc
    56101 agcaaataat ggagaccctg tttgggtaat aatgactggt atattaattg aatcacaaga
    56161 taatgagaaa tcaatggtct atatattgta ttcaaaaatt aatgagttaa aaataaagca
    56221 agaagaacta tctgatatgg aaaaagagag tacagagaat tttaaatgga tgatgtcaga
    56281 gtatgctggg aatgtttata ttagcgatat ggatacatat gaattactat acttaaataa
    56341 gcactcatgc aatactttac aggcatcagc aaatgaactt attggaagaa aatgttatga
    56401 ggtaattcaa ggtagaactt cgccatgtcc gttttgtaca aattcgtatt taaaaaaaga
    56461 tgacatatat gaatgggaat tttataataa aaaactgaaa cgaacattta taattaaaga
    56521 ccgtatgttg aattggcaag ggcgaagagt tcgtattgaa ttatcttatg atatgtatag
    56581 tgctgaatat aaattagcaa aaaaagatca ggaaagagaa tcaattttga aaactattcc
    56641 agcaggaatg gttagattag atgcaagaga ttatcttact atactttggt gtaatgatat
    56701 atttttgaat atgattgaat atacaaagga acagtttgca gaggaactta ataatcaatg
    56761 tggatattta ttttctgaag attataaacg tagtaagaaa ctggcacaag atttgaagga
    56821 gtctggggat aatgttgtat ttgaagcaaa aatatataca cgttcaaggg aagaacgtat
    56881 atggactgtt acattgtgtt atatcagtgg ggaagacagt tgggatggaa taccatcttt
    56941 ttatagtata ggtattgaca taacaaagga aagaaaacag attgagaaat tacagcatat
    57001 atcagagaaa gatgcattaa caggaattta taatcgtgct gagactgaaa ggcagattaa
    57061 gaaatatttt gaaaaaaatt taaatgttat gggtgcactg tttatgattg atacagataa
    57121 ttttaaacag attaatgata cagaagggca tatgattgga gatatagtac ttactgagat
    57181 ggcatcaggt atgaaaaaaa taatgcgtga cagtgatgtt gttggaagaa taggtggaga
    57241 tgagtttaca atttttatga agaatatttc ctcagttaaa gatgcagaaa agaaagcaga
    57301 agaactattg tatatgttcc gtcatctatt tcagaaagaa aaaagttttc taaaagtaac
    57361 ttgtagcata ggaatagcta tatatccaaa ggatggtact acattcaagg aaatatatgc
    57421 aagagctgat aaagccctgt atcaagcaaa aaatatggga aaaaataatt atgtaatcta
    57481 caaccaagat tattttaaag aattagaaga atttgattgt tcttctcttg gtacagttat
    57541 tgattcagaa aaacaatacg ctgaatatcc tgataatctt acacgttata tattccgtat
    57601 gctttatcag actgatgata tagaccaggc gattaatatg atacttgagg ttgttgggaa
    57661 acagtttgat gtaagtcgtg tttatatttt tgaaaataca gaagatggta gatatacttc
    57721 taatacttat gaatggtgta atgaaggaat ctcttctcaa atggcttatt tgcaaaacag
    57781 caattatcaa gactatgagg attatgaaaa gctttttgag gatgaattag ttttttattg
    57841 tcgagatatc catacattaa gtcctaaact agaagaattg ttttctagtc aaggtatcca
    57901 ctctacactt caatgtgcat ataaagaaga tagagttttc agtggatttg ttggatttga
    57961 tgaatgcaca ggactacgtc tatggtcaca agaggaaata agtacattat cattgatttc
    58021 tcaaattata tcaatgtttt tacaacgtaa aaaaaataat aaacttaatc aacagattca
    58081 acaataccag aatattttag ataatattga ccagtgtatt tgtgtgatta ataaagaaaa
    58141 taatttttta ttatatgtaa ataaaaaatt taaaaataca tattctaaat tccaaattgg
    58201 acaaccttat tatcttgatt ctatagatat tcataagata tccattatat ggaataaaaa
    58261 agaagcatac ctatgtacta gcacgattta atggtaaagt aaagtttata ttggacttaa
    58321 attaaatttc gttttaaata agatattatt ttagttgctt actgaaaaga ctagaatcta
    58381 tattaatgaa ttatactaat tttataccac tattaaaata ttgtttgcta aaaataaaaa
    58441 atagccttaa aacagttgat tataaaaaat taactgcttt aaggctattt ttatctttgt
    58501 gacgaaatag acacttgcca tttagaatgt gacaatatag tagttgttta gaaaaggcac
    58561 aaagcattat actttaacta aagtaaaatg tattttgctt ttagaataaa aacaattagg
    58621 agggagctat aattgaaaaa gataatatat gtattattta caattgaact attaatagta
    58681 tctttattag gtctaaatat agttaaagat aatgaaatta ataatatttt atataacgat
    58741 acaacaagta tatctgtaat gtttaaagat tataaaaagt taaataaaaa ttatagtaag
    58801 tggattaaag atattgcaga tgaaaataat gtggctatat caaagtatgt ttttaataat
    58861 aatgaaaaat tatctatata tacgactgat acaagtttga ataacaatat aaagttaaaa
    58921 tcaggaaaat ttcctaatac taattcaaat gaatttatta gtaatataaa cactaataat
    58981 agtaatcaag taggtaaatt ctcaactatg agtaaagaca tatcaatttt aattagggat
    59041 tttggtaaaa taagtgaagt tggagaatca ggaatcttat atatttcaac tcaaaatgaa
    59101 gatacaataa ataaaatatt aagagaacta aatgtagaca gaagtatttt tgtagcaaga
    59161 ttacatgata gatatgttaa ctcaaattta tacttaaatc cttcaataat tagagattta
    59221 atactaatta tcctttgttt cttggctaca ataatacatt attcaattag tgtgagtaga
    59281 gaggcttcta ttttaagatt aaatggatac tctaagctag atataattgc tagagttata
    59341 aaaaatatac ttagaattat gattttatca tctgtcacag cattattaat atatataatc
    59401 tatattttaa aattaaatat aggtgttaga gcatgcttat actttgctat gttttcgatt
    59461 atatgtattt tgataaatat tttgatatct atattaatag ttggttttaa tagtagaagt
    59521 tctaaatatg tgctatctct aaatggaaaa aaatcttatg gttttgtaaa tataatgcat
    59581 ttcacattga aaattgtatt tgtatcattt cttatattat ccataaataa ctgtatttta
    59641 aattataata tgctacaaac tcagttagga aatctatctg agtgggataa agcaaaaaat
    59701 gtttataatc ttactcttaa agatacaggc gaacaatctt taggaaagga agaagtaatt
    59761 aaaaatgcca agattaaagg tttctataaa aatttggtag aagaaaaaga tgctttctta
    59821 atagattcaa ctaattttga aaaacttgaa gatggaagtt acatgtatga aataaattca
    59881 aagggtaaaa acccagaagt aagtcaatat ggtaaaaata taaaaataaa taaaaactat
    59941 cttaaagtta accctattta ctcaaatggc aaagaaatat ttaatctaat cgattatgac
    60001 gataagacta taaatttatt agttcctaaa aagttacaag tacatgaaaa tgagattaaa
    60061 aaagagttta gagaattatt ttattttgaa aaaatagaag tagaaaatat gtacaataaa
    60121 gagttaaata gagagttaaa taaaacaaag aagtccgatt taaatgttaa tataatatat
    60181 gtagataata atcaaagcta ttttacttat aactcccttg ttatggatga caataggaat
    60241 ctcattgatg acccaatagc aatagttgac atagataata ttgatgattc tttttatctt
    60301 tcttatatat ctagatgtgt atattttaat tctaagaaat tagatgccct tgcagatata
    60361 agtagcatta ttgaagctca aggtgtagaa gcgcatatcc aaagtttaca tgctgtttat
    60421 aatgagtatg gtttagaaat aaataaacta gaaaaatatt tgaatagtga aatttttact
    60481 ataataataa tagcaatatc aaacttaatg attacctaca atatagtagc tagctactat
    60541 gaaagaaata aatataagtt atatattaaa aaaatatttg gttactcaac tacagctaga
    60601 agtatgttgt taatagtctc attaatatta acaaacatta ttccaatagg cattatatca
    60661 acaagagtag atttaagtaa taatattatc ttatttggac ttctaatatt agttatagaa
    60721 gtaattgtat ctattgtatt agacaagatt atctcaaata gttcatttaa taaaattata
    60781 aaaggagaac attaaaaaga tgatttcatt aataaatata tctaaaaaat ttaaagataa
    60841 atctataata gacaaattta acctagaaat ttctaagggc gagtttgtag cgataacagg
    60901 aaatagtggt tcaggtaaga caactttact taatataatg ggattattag aaaaacctaa
    60961 ttctggtgat attataataa ataatataaa aaatccaaat agtaaacaga taagaatttt
    61021 acaaagggat ttttatggct atctatttca aaattatgct ttaattgaga atgaaaatgt
    61081 tgaaaataac ttgaaaattg ctttaaagta tcaaaaaaat atcaatcata atgaaaaaat
    61141 aaattacgca cttgagtctg taggtcttag aaaatacaat aaaaaaaaga tatacgaatt
    61201 gagtggagga gaacaacaaa gggtagcatt agcaagagta atattaaaag aatgtgaagt
    61261 aatatttgca gatgaaccta caggtaattt agataaaaaa aatagagaca tagtatttga
    61321 tatacttaaa agtctaaata agaatggtaa aactatcgta tttgtaactc atgatttaga
    61381 tttatcggag caggcagata gagttataaa attgtaataa tataaactat aataaatata
    61441 agaaagagat tacagctaaa ttaagtttaa taataatacg aatagaattt aaacattaag
    61501 taaattagta gtttgtaaat ataagtataa tatgatatca taaaggctca aaagaaattt
    61561 tatataataa gaaatctaaa aataacaaat ggaggacata taaagatgga aaatttacca
    61621 aattgcccga aatgtaattc agaatatact tatgaagatg gaactctttt agtttgtcca
    61681 gaatgctctc atgagtgggc attaggattg ggagctgaag aagattcaaa tattatcaaa
    61741 gatgtaaatg gaaatgtatt aaatgatgga gattctgtta cagtaattag agaccttaaa
    61801 gtaaaaggaa gttcatcatc tataaagatt ggaacaaaag tgaaaaatat ccgtttaatc
    61861 catgactcat cagatggaca tgatatagaa tgtaagatag atggttttgg agctatgaag
    61921 ctaaagtctt ctgttgttaa aaaagcgtaa tattataaat aagctgtagt gtttattgtt
    61981 tttcagtaca gtataaaacc ataagaatct attaagtaat aaaagtttgt ttatttatct
    62041 ttatattttc ttatggtttt attaaatata aattttattg aacaccaaaa tattctctcc
    62101 tctacaaata agccaatctt atttaaacta atatactttg tactatttat actgaaattg
    62161 taaatttaaa tgctatgtta tttaggtttg tatagttaat ttatatattt ctgattttat
    62221 aaattgtatt tattattata tcttgattct aaaatcatta aaaatttcaa cttctataaa
    62281 gatttacaat ttatcaaata cattatgagt atataaacaa tttattatta cagtgctaca
    62341 tttaaaataa gtcttagtat aaaggtattg ttacaagtat aaagaaactt atgtatgcta
    62401 ttggaataaa taatacctta aattataatt aagaataaga actgttaaat aagggacttg
    62461 attatcattt agttatagat aatataatat taaaaataaa gtttaagagg agaaaaaata
    62521 tgatagatat acataaaaat atatatgata ataagttatt tgaggagcta aagattgact
    62581 gtaagaagtg ctttggactt tgctgtgtag ctctttattt ttctgcttca gatggatttc
    62641 ctatcaataa ggaatcagga aaaccctgta ttaatttaca accagatttt aaatgttctg
    62701 tacataatag tcttattaag cgaggtttta aagggtgtac tgcatatgat tgttttggtt
    62761 caggtcaaaa agtagcacaa gtaacatata aggggataga ctggatgcaa tcaccagaac
    62821 taacaaatca aatgtctgaa gtgtttttaa ttatgagaca attacatgaa atgttatggt
    62881 atcttaaaga agcatctgta ttaaatatat cagatacaat caaatcaaaa attgatttaa
    62941 taattgaaga aactgaaaag ataactaata tgggcccaga acagataatt aatttggata
    63001 tcatatcaca tagaacaaag gttaatttat tattatcaca agcgagtgag tctatgatgg
    63061 gaaaggttaa atcatttatc aagacttcta ctcttaaaaa catgaaaaaa ttaagtaaaa
    63121 atatagattt aataggagca gaccttagaa aaataaatct aataggagca gatttaagag
    63181 gtagatttct aatagcagca aatttaagaa atacagattt gagtggggca aatttaatag
    63241 gagcagactt aagagattgt gatattagag gtgctaatct tgaaaatagt atatttttaa
    63301 cacaattaca agtaaatact gcaaaaggag attctagtac gaagttacca gcttcactaa
    63361 tacgccctaa atactgggaa aaataattaa attaatacat aattttacaa aatatgaact
    63421 tttttgactt taattcatat tatacattag agattcttta caagaatttc ttaatataat
    63481 atagggagag atataaaaat gagttatcaa aattataaat gtgaaagaga ttatgtgtat
    63541 gatgattata aatacaataa gtgcaacaag tgctataatg attatgagga aatgacacat
    63601 gttcatgaat attcagaaag tgttaagtta gcagaagaat gtgaggatag acataaccac
    63661 cgtgcagcag gggttactgg tgaagttata ccaataaatg gaggtacaaa tcatgttcat
    63721 aaaataaatg ataatgtaga tttccttgac catttccata agatatgtgt tacaacaggg
    63781 ccagcaatta gaatacctgg aactgataaa cacattcact taatatgtgg agaaactact
    63841 gttaatgatg gtcattgtca taaattcctt tttactactc aaatagaagc acctttagta
    63901 taagctgatg tgaattattg tagtgaattt gctagattat agtataatat ataatagata
    63961 atatttaaac ttaatgagga ctatgatatt taaccttcgt agtcctttct aagttttgta
    64021 taaaaaagtg ttatgcaatt aaaagtgata tagggaggaa atttttatga aatctggaat
    64081 aattcttgaa atgaaacaaa taaattcaac agaatatgac gaaatgttgc aagtctggga
    64141 atcatcagta agagcaacgc atgatttttt aacagaaaaa gatattgaat ctttgatacc
    64201 attagttgag attggactta aagaagtaga aaatatagtt tgtataaaag ataatgatat
    64261 aataaagggc tttataggaa tagataaaga taaaattgag atgctcttta tagaagataa
    64321 atatagagga aatggtattg gtaaaaaatt aataaaatat gctatagata aatacaatgt
    64381 aaaatatgtt gatgtaaatg agcagaataa aaaagctgta ggattttata ttcacttagg
    64441 atttaaagtg tttgataggt ctgaaataga tggacaaggg aacccatttc caatactaca
    64501 tatgaaatta atttaaagtt atacttccca cttattcgca aaaatattta cttaaatttt
    64561 tatacaaata aaagtcgtga cagtcttagg acacgacttt tttactacac tattaaattg
    64621 aaatttatct gttctatatt atgattatta gatgtagttt ttttatttta actatgtact
    64681 taaataccaa gtatacccat acctatcaag tacttcagca gcgccatcat tttgatgtgg
    64741 tggtgggtgt ggtaaaaatt cttgtacaag tgtaccacct tcggcaagtt ttacagatat
    64801 ttcttctatc gcttctcgag atggtagaac aacacaaatc gccatgccag aaattacaac
    64861 aggcttgtct gtatccgcac ccattataca accttcgtat tttgtgaaag taacacttgc
    64921 gtgcataata ggattgtttg gattgctgtc taatcgcgca aatatagttt ttcctcctcc
    64981 gaaagcctca gcataaaaat taaatgcttt ttcacaagta ccattaaata ttaaatatgg
    65041 agttagcatg accaatatat cctccttgat atagaataat ttatagttgc acctgataat
    65101 ctaaattatg atttagtaaa ttgtatcata gggaaacctt gaagtatata attttttatt
    65161 attatattat acaaatttat taatttaaaa aaatgttata tgtacggaag gtttacagga
    65221 taaaatataa taaaaagatt aaggtgacat tataaaaaat gtatattgac attgacgcta
    65281 cgtaattgta tatactttgt cttaaaggag atggtaaata tgaatattat agaaattcgc
    65341 tcagataaaa tatacaagaa gataatggat gcaccaataa acaaaaaaga agatatatac
    65401 agatatgaat taatgaagcc ttttgaattt aagtggaagt gtatgaatgt tccaatagtt
    65461 gctagacaga aaggtggata tgatgtaatt atagcaagtg aaatgttagg ggttttatcg
    65521 cctaaggata ttgatgaaaa gcaaaaaaag aatataaatg tgttatctgc tgataaaatt
    65581 tggggcactt gcaaagaaac catagaaaac tctataaatg cttttataaa agaagggtat
    65641 gatttaaaca ttaaggacta taaatattca atattattgg cgaatccaaa tagtccttat
    65701 acaatattaa gtgatggata ctggggtgat ggtgggattc ctggatatat atttctatca
    65761 ttggttccta atgaatatac tatcaataga ttaccagtat taatagcaca tgaatgtaat
    65821 cacaatatta gatttcagtt tatagagtgg aataataata taacattaga agaaatgatg
    65881 ataaatgaag gtcttgcaga aaattttgca acatggatgt ttggagagga aatgttagga
    65941 ccttgggtca gtagaacaga tatcgaaaca ttaaatactt atataaagcc aataataaaa
    66001 agtgctttaa aagaaactgg atttcaaaat ataacatctt atctttatgg tgatgatata
    66061 gctaaaatgc aaggatattt tccagtaggg ttgccttatt gtgcaggata tgcttgtgga
    66121 tattatatga ttaagtatta tttagaaaag acaaataaat caataatcga agcgacttta
    66181 ttgccttata gtgagataat cgaagcagta aaagagtttt gggaataaat tttataaatt
    66241 gcataatttg aaataaatta tgcaattatt ttatttttaa gaaaaaataa attgacaata
    66301 atttataaga aatatacaat aatatatata aagaaatatt tcaatattta aaagttttaa
    66361 gatttcatat ctagagtagc taacattaca tgttagtttc ttgttactta tctaattact
    66421 ttatatttcg tagttatata taaaattact at
//
LOCUS       DAYAOO010000011        64552 bp    DNA     linear   BCT 12-OCT-2024
DEFINITION  TPA_asm: Clostridioides difficile isolate ST8-SSI-h139-18
            SAMN40601845-rid21577343.denovo.011, whole genome shotgun sequence.
ACCESSION   DAYAOO010000011 DAYAOO010000000
VERSION     DAYAOO010000011.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN40601845
            Sequence Read Archive: SRR28438827
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 64552)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 64552)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-MAY-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-MAY-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002157583.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002157583.1
            Genome Coverage       :: 163x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/11/2024 16:19:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 4,038
            CDSs (total)                      :: 3,963
            Genes (coding)                    :: 3,930
            CDSs (with protein)               :: 3,930
            Genes (RNA)                       :: 75
            rRNAs                             :: 6, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 60
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 33
            CDSs (without protein)            :: 33
            Pseudo Genes (ambiguous residues) :: 0 of 33
            Pseudo Genes (frameshifted)       :: 7 of 33
            Pseudo Genes (incomplete)         :: 25 of 33
            Pseudo Genes (internal stop)      :: 11 of 33
            Pseudo Genes (multiple problems)  :: 8 of 33
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..64552
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN40601845-rid21577343.denovo.011"
                     /isolate="ST8-SSI-h139-18"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Denmark"
                     /collection_date="2018"
                     /collected_by="Statens Serum Institute"
     gene            205..1029
                     /locus_tag="ACGI5H_000788"
     CDS             205..1029
                     /locus_tag="ACGI5H_000788"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729220.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HFG9696513.1"
                     /translation="MEVYALVGSSGTGKSFKALEFAYENDIEYIIDDGILIYKNKVLA
                     GISAKQANTTIEAVKRAIFYNLEHRQEVREAIKKENIRKILIIGTSKKMVNQIVERLS
                     IGRVCKFINIQDISTKYEIEIAKQARKEGNHVIPVPAVEIKSMASGLSINSLKRLFRK
                     GSNRNMVVLEKTIIRPTFSYIGKFYISADVIKQIIEYEVYNFGSIDRINKINIENCNN
                     FMNIFVSININDLETIKKIEDIQQTIKKSIEKMTLVNVQKIDINIHKIKKINFLQC"
     gene            1158..2423
                     /gene="gluD"
                     /locus_tag="ACGI5H_000789"
     CDS             1158..2423
                     /gene="gluD"
                     /locus_tag="ACGI5H_000789"
                     /EC_number="1.4.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420866.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD-specific glutamate dehydrogenase"
                     /protein_id="HFG9696514.1"
                     /translation="MSGKDVNVFEMAQSQVKNACDKLGMEPAVYELLKEPMRVIEVSI
                     PVKMDDGSIKTFKGFRSQHNDAVGPTKGGIRFHQNVSRDEVKALSIWMTFKCSVTGIP
                     YGGGKGGIIVDPSTLSQGELERLSRGYIDGIYKLIGEKVDVPAPDVNTNGQIMSWMVD
                     EYNKLTGQSSIGVITGKPVEFGGSLGRTAATGFGVAVTAREAAAKLGIDMKKAKIAVQ
                     GIGNVGSYTVLNCEKLGGTVVAMAEWCKSEGSYAIYNENGLDGQAMLDYMKEHGNLLN
                     FPGAKRISLEEFWASDVDIVIPAALENSITKEVAESIKAKLVCEAANGPTTPEADEVF
                     AERGIVLTPDILTNAGGVTVSYFEWVQNLYGYYWSEEEVEQKEEIAMVKAFESIWKIK
                     EEYNVTMREAAYMHSIKKVAEAMKLRGWY"
     gene            2636..3226
                     /locus_tag="ACGI5H_000790"
     CDS             2636..3226
                     /locus_tag="ACGI5H_000790"
                     /inference="COORDINATES: protein motif:HMM:NF017390.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M56 family metallopeptidase"
                     /protein_id="HFG9696515.1"
                     /translation="MHFKSKDLNLKYLVLFLKIVYWFNPFIYIMEKYMDLDCELYCDE
                     RVLKNCTVQQKQEYALTIVNSMKRSTNFSNKFVAGLNKQSDIRKRVINMFSEKHKNGI
                     LRALIISLFSSITFFKFDSTSIIEENDFLERSRYTFEGRQEDMFVTIDFIYADVPIKL
                     RKEHEENCRVNGIVPKDSDSIEIIPRFYKDCMDLKK"
     gene            3557..4690
                     /locus_tag="ACGI5H_000791"
     CDS             3557..4690
                     /locus_tag="ACGI5H_000791"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888023.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M56 family metallopeptidase"
                     /protein_id="HFG9696516.1"
                     /translation="MSNFILNGIFRTVIVSSLSILMILIFKKNVFKRFSKKFNYYIWM
                     IVVIKLFLPFTYYTFTINILRSKKHININNINLEGFNNVSTISNNIILYTWIITVVVY
                     LIYTIFKYIKLKNLINDLSYDVDDGEIVNLYKNILEEFNITKDIKLKYSYEVETPAFF
                     NSCVLLPPHEYKLKELDWIFRHELMHFKSRDLYLKYVILFLKTVYWFNPFIYIMDKHI
                     DLDCELYCDERVLKNRNSEEKKDYALTILNAMRKGSNTSNKFIAGLHKQSDIKKRVMN
                     MFNEKYKNGILMALTLCLLSSITFLKVNSTSIVNLNILPKGMEEKDVTNSAIVTMIEF
                     TYAEAPKSMREEHKINCEFLGLIPKDSDKIGVGIEYYDSLLND"
     gene            5606..6628
                     /locus_tag="ACGI5H_000792"
     CDS             5606..6628
                     /locus_tag="ACGI5H_000792"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729223.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NlpC/P60 family protein"
                     /protein_id="HFG9696517.1"
                     /translation="MKKKILIPVFASVMALSVSSIVNADEVNDSSQNKDDKTNTELNL
                     GEYKEVKYKVAKIKDGVAIKIREEGQVQNIAYSGDEFTVLGTQGEWVKVKVEDGEGWL
                     ATRYVDISEGVGYTNADKVNLRKDKSESSEVIEELEKGSSLLVLEDNGDWLKVKDGET
                     EGYVKSSYISDKAPVIEEPQVNPSIDQNVDSTNNNQQNNANTNQQNNNSNVPTANSNA
                     VQAVLNLAYSKQGCPYVWGAEGPNTFDCSGFTQYVYRNAVGKNIPRTSKAQSKYGQTV
                     SKANLQPGDLVFFTTNGSGSVSHVGIYVGGGNMIHSPSTGKTVSVTSINSSYYTARFV
                     TAKRIL"
     gene            6924..7844
                     /gene="pyrB"
                     /locus_tag="ACGI5H_000793"
     CDS             6924..7844
                     /gene="pyrB"
                     /locus_tag="ACGI5H_000793"
                     /EC_number="2.1.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434504.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004070 - aspartate carbamoyltransferase
                     activity [Evidence IEA];
                     GO_process: GO:0006207 - 'de novo' pyrimidine nucleobase
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate carbamoyltransferase"
                     /protein_id="HFG9696518.1"
                     /translation="MLKSRNLIQPEDFSIEEIDEILELAQKIIDNPSKYSRICEGKLL
                     ATLFYEPSTRTRLSFESAMNRLGGRVVGFSEPNSSSASKGETLGDTMRIVSGYVDIIA
                     MRHPQSGAASEAARYTEVPFINAGDGKNQHPTQTLTDLLTIKSLKGTLESHTIGLCGD
                     LKYGRTVHSLVKAMARYKNTKFVFIAPEELKMPDYIKEAIKGHAYYETNNLDDVIGSL
                     DVLYMTRVQQERFEDKSEYERLKNYYILNKAKLEKASKDMLVMHPLPRVNEIDIDVDS
                     DDRAVYFKQAKYGMYVRMALIIKLLGINED"
     gene            7883..8575
                     /locus_tag="ACGI5H_000794"
     CDS             7883..8575
                     /locus_tag="ACGI5H_000794"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420878.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA];
                     GO_function: GO:0050660 - flavin adenine dinucleotide
                     binding [Evidence IEA];
                     GO_function: GO:0051537 - 2 iron, 2 sulfur cluster binding
                     [Evidence IEA];
                     GO_process: GO:0006221 - pyrimidine nucleotide
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroorotate dehydrogenase electron transfer
                     subunit"
                     /protein_id="HFG9696519.1"
                     /translation="MYKILENIYIGEDMYRMKVKGNFEGKMGQFYMLRAWDTYPVLSR
                     PISIHDIDEEGITFLYKVVGEGTQILSNLKVNDNIKLEGPYGNGYAKVDGKVALVGGG
                     IGVAPLYLVAKNIKNCDAYLGFREDVILEDEYKQVCNKVYTTVGNTFVTDIIDVEKYD
                     YILTCGPTPMMEKLVKMVEGTKTRIMVSLENHMACGVGACLVCTCKTNGGNKKTCKDG
                     PVFWGEDVIFNG"
     gene            8568..9470
                     /locus_tag="ACGI5H_000795"
     CDS             8568..9470
                     /locus_tag="ACGI5H_000795"
                     /EC_number="1.3.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860662.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004152 - dihydroorotate dehydrogenase
                     activity [Evidence IEA];
                     GO_process: GO:0006221 - pyrimidine nucleotide
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroorotate dehydrogenase"
                     /protein_id="HFG9696520.1"
                     /translation="MGNLSVKFGSVEFKNPVIMASGTFGFGKEYNEIYDIQKLGGISS
                     KGLTLNKKPGNNGMRVHETSSGMMNSVGLENPGVQGFIDYELPFFSKLDLVRIANVGG
                     GTLEDYLLGVQMLNDKPIDIIELNISCPNVKAGGMAFGIKNEVAREVVREVRNITKLP
                     LVIKLSPNAEDIVGMAKVCEEEGADGVSLVNTFKAMAIDIKNRRPVFENVYAGLSGPA
                     IKPIALRMVHEVCKNVNIPVMGMGGITKATDAIEFIMAGATCIQVGTANFMNPRIGIE
                     IIDGINEFMDREGIKSLDEIRGII"
     gene            9555..10139
                     /gene="pyrE"
                     /locus_tag="ACGI5H_000796"
     CDS             9555..10139
                     /gene="pyrE"
                     /locus_tag="ACGI5H_000796"
                     /EC_number="2.4.2.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420885.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004588 - orotate
                     phosphoribosyltransferase activity [Evidence IEA];
                     GO_process: GO:0019856 - pyrimidine nucleobase
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="orotate phosphoribosyltransferase"
                     /protein_id="HFG9696521.1"
                     /translation="MSKVDVVDILKKSDALLEGHFLLSSGKHSNRYVQCAKVLRFPEY
                     AAEVLSTVVEQIKDLDIDLVVGPAMGGVIVSYELGRQLGKEAVFTERKDNTMELRRGF
                     EVKKGAKIIIAEDVVTTGKSTMETKRVLEALGGEVVGVACIADRTNHDIGMPIYSAIK
                     LDIQVYESDECPLCKEGKLPVVKPGSREFKELGM"
     gene            10353..11279
                     /locus_tag="ACGI5H_000797"
     CDS             10353..11279
                     /locus_tag="ACGI5H_000797"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729225.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ketopantoate reductase family protein"
                     /protein_id="HFG9696522.1"
                     /translation="MKNQLNENHKKVVFFGVGAVGATFAEQFFNSKYDFKILCDNERK
                     KRYLEEGFIINGKRYDFDYVTKDEYKQEADFIIIGLKYNNLKENIKELDGLVGKNTVI
                     MSLLNGVDSEEIIGERFGIEKMVYSYVTNIDAKKINNNIIHTTNGIIVFGNKDNSEDR
                     KTNIITEVFDDVNIEYTLSKDIQRDMWWKYMVNIGVNQTSAILGAPYGVFQSSEHLRE
                     LAKSAMREVVAIAQAKDISLTEDDVEHSLHRILEHSKEGRTSMLQDVEAHRLTEVDMF
                     SKNICKLGKKYNIPTPINQTFFYMIKVIESRF"
     gene            complement(11331..12221)
                     /locus_tag="ACGI5H_000798"
     CDS             complement(11331..12221)
                     /locus_tag="ACGI5H_000798"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435002.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HFG9696523.1"
                     /translation="MFEELKTFVAVVEYKNFTKAGEYLNLSQPSVSKHIKNLENYFKV
                     VLINRSIKQKTIFITESGQILYKRAKEILNLLNITYHDVSQVSDAITGHLKIGASLTI
                     GEYILPNFLALFSKKYPDIDVEVFIKNTSIVSSHVKDYILDIGLIEGTCSSPSFIQEY
                     FFEDKMVLALPYKSHLLKDFSFDKLQNQKWIVREDGSGTRDYLDMFLSVKEIIPKSMM
                     VFGSNYAVKESVRNNLGITIVSNLVTSLPVLNNELSVIELGSSYNRHFSYIFPKDITL
                     SKAATIFIEELKIFSNLNSI"
     gene            12409..13440
                     /locus_tag="ACGI5H_000799"
     CDS             12409..13440
                     /locus_tag="ACGI5H_000799"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420895.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="putative sulfate exporter family transporter"
                     /protein_id="HFG9696524.1"
                     /translation="MLKKKSSLTLKTIREILPGLFVSVLVGYISIFISILIPKVGAAS
                     ISIFLGMFVGNLFLNQKVFQKGYKFSETDLLSYSIVLLGATLSVSTLIDLKVSGILFI
                     ILQMTITIIAALYIGKKLGFEENFRFLMASGNAVCGSSAIGATVPVVNATDKEKGIAV
                     TIVNVTGIFLMFLLPIISQFLYSHELVKTSAMIGGTLQSIGQVVASGAIVGENVKDLA
                     TIFKIVRVIFLVVVVLVFGHMKNQSNREILEEEKDEIKKKKVTIPWYVIGFFITCALF
                     SMNIIPKEVSVLCKEISNKLEIIALAAIGLKVNVKDLVKQGKEVSLYGLFVGIVQVVS
                     AVVLIKIFI"
     gene            13734..14609
                     /locus_tag="ACGI5H_000800"
     CDS             13734..14609
                     /locus_tag="ACGI5H_000800"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895282.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003684 - damaged DNA binding [Evidence
                     IEA];
                     GO_function: GO:0008534 - oxidized purine nucleobase
                     lesion DNA N-glycosylase activity [Evidence IEA];
                     GO_process: GO:0006289 - nucleotide-excision repair
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA glycosylase"
                     /protein_id="HFG9696525.1"
                     /translation="MNVYEKGNGVILEGVTDFDPVHIFECGQCFRWHKQEDGSYTGVA
                     KGRILNVKKENDKIYLNNTNLKEFNSIWYNYFDLGTDYTEIKNKLKNMDEYLNKATEF
                     GWGIRILRQDGWEMLISFIISSNNRIPMIQRAIENLSRKFGKYIGEYEGNEYYAFPTP
                     EELNKASQEEIRACQTGFRDKYIKSTTQAVIENNDEVSEYTNLSTEDCRKELLKFNGV
                     GPKVCDCIALFGMQKYDSFPVDVWVKRVMQEFYIDEDMSLPKMRTYGIDKFKEMSGFA
                     QQYLFYYARELGIGK"
     gene            14627..16117
                     /gene="cls"
                     /locus_tag="ACGI5H_000801"
     CDS             14627..16117
                     /gene="cls"
                     /locus_tag="ACGI5H_000801"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420900.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008808 - cardiolipin synthase activity
                     [Evidence IEA];
                     GO_function: GO:0016780 - phosphotransferase activity, for
                     other substituted phosphate groups [Evidence IEA];
                     GO_process: GO:0032049 - cardiolipin biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cardiolipin synthase"
                     /protein_id="HFG9696526.1"
                     /translation="MGVIGTIFLFYLIISYLAGAIISVIILLENRDPAKTMSWLLMFI
                     IFPGVGLMIYAISGRNIRKRKLFKTQKLANNIKEKKLFDTLEKITEIVELEKESIKQN
                     KLLRDEEDGSYRKRVINMLLKTGMFPFTKNNKVDVFVDGNEKFKRLIEDIREAKDHIH
                     LEYFIIKDSEIGRVLKEELIKKAKEGIKIRILYDDVGCWRFWFNRKFFREMREVGIEI
                     AAFLPTKFPIIGGKLNYRNHRKIVVIDGIIGYTGGINIGDEYLGKNDKFGYWRDTHIR
                     IKGISVYMLQMTFLIDWYYTTKEVLVTKNYFPSVGNVGESMIQVVASGPDSDWEDIHY
                     AYFSAICQARKNVYIETPYFIPDESLLKAIKSAALSGVDVRIIFPKIADHKIVNIASY
                     SYFEEILRAGGKVYLYNKGFIHSKVVIIDDKIASAGTANMDLRSFMLNFEVNAFIYDE
                     EVIRVMTDDFFEDLSHCEELNLEVFKNRNIIQKIKESVARLFSPIL"
     gene            16310..16594
                     /gene="groES"
                     /locus_tag="ACGI5H_000802"
     CDS             16310..16594
                     /gene="groES"
                     /locus_tag="ACGI5H_000802"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012062101.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="co-chaperone GroES"
                     /protein_id="HFG9696527.1"
                     /translation="MKIRPLADRVVIKKVEAEEKTASGIVLPGAAKEQPQIAEVVEVG
                     PGGIVEGKEIKMELTVGDKVIFQKYSGTEVKIEGQEYTILRQSDVLAVIE"
     gene            16627..18255
                     /gene="groL"
                     /locus_tag="ACGI5H_000803"
     CDS             16627..18255
                     /gene="groL"
                     /locus_tag="ACGI5H_000803"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729227.1"
                     /note="60 kDa chaperone family; promotes refolding of
                     misfolded polypeptides especially under stressful
                     conditions; forms two stacked rings of heptamers to form a
                     barrel-shaped 14mer; ends can be capped by GroES;
                     misfolded proteins enter the barrel where they are
                     refolded when GroES binds; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology.
                     GO_function: GO:0140662 - ATP-dependent protein folding
                     chaperone [Evidence IEA];
                     GO_process: GO:0042026 - protein refolding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="chaperonin GroEL"
                     /protein_id="HFG9696528.1"
                     /translation="MAKEIKFSEETRRALEAGVNKLADTVKVTLGPKGRNVILDKKFG
                     SPLITNDGVTIAKEIELEDRFENMGAQLVKEVATKTNDVAGDGTTTATVLAQAIIREG
                     LKNVTAGANPILLRKGIQKAVTVAVEELKNQSRIVETQEAISQVASISAGDEEVGKLI
                     AEAMEIVGKDGVITVEESQTMNTELDAVEGMQFDRGFVSAYMVTDVDKMEAVLNDPYI
                     LITDKKISNIQELLPVLEQIVQQGKKLLIIAEDVEGEALSTLVVNKLRGTFDVVAVKA
                     PGFGDRRKEMLQDIAILTGAQVISEELGYDLKEADLSMLGRASSVKVTKESTTIVDGS
                     GDKKAIEDRVTQIKHQVEQTTSDFDREKLMERLAKLAGGVAVVKVGAATEVELKERKL
                     RIEDALNATRAAVEEGIVAGGGTAFVSVIPAIGTLIESLEGEVKLGAQIVKKALEEPL
                     RQIAINAGLEGAVIVQNVVNSEAETGFDALNEKYVNMIEAGIVDPTKVSRSALQNAAS
                     IASTFLTTESAVADLPEKEDAGMPGMGGGMPGMM"
     gene            18517..19257
                     /gene="larB"
                     /locus_tag="ACGI5H_000804"
     CDS             18517..19257
                     /gene="larB"
                     /locus_tag="ACGI5H_000804"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425348.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="nickel pincer cofactor biosynthesis protein
                     LarB"
                     /protein_id="HFG9696529.1"
                     /translation="MDLRKLLEEVKNENIDIDFALEKLKDLPYEDLGYANIDHHRELR
                     NGYPEVIYCEGKSDEHILGIIDKMNQKSSNILGTRCRKETFLKIKEIYNHAEYEEASK
                     ILKIQNHDIENIGKGKIVIATGGTSDIPVADEAYHTAKFLGNDVDRIYDVGVAGIHRL
                     LNKRHKIDSARVIVAVAGMEGALASVIGGLVDVPVIAVPTSVGYGANFGGLAALLAML
                     NSCASGISVVNIDNGFGAGYLASMINKL"
     gene            19392..20524
                     /gene="larC"
                     /locus_tag="ACGI5H_000805"
                     /pseudo
     CDS             19392..20524
                     /gene="larC"
                     /locus_tag="ACGI5H_000805"
                     /inference="COORDINATES: protein motif:HMM:NF014072.4"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="nickel pincer cofactor biosynthesis protein
                     LarC"
     regulatory      20584..20685
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00167"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="purine riboswitch; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="guanine and/or adenine"
                     /db_xref="RFAM:RF00167"
     gene            20906..22441
                     /gene="guaA"
                     /locus_tag="ACGI5H_000806"
     CDS             20906..22441
                     /gene="guaA"
                     /locus_tag="ACGI5H_000806"
                     /EC_number="6.3.5.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888031.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003922 - GMP synthase
                     (glutamine-hydrolyzing) activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016462 - pyrophosphatase activity
                     [Evidence IEA];
                     GO_process: GO:0006177 - GMP biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine-hydrolyzing GMP synthase"
                     /protein_id="HFG9696530.1"
                     /translation="MKHELVLVIDFGGQYNQLIARRVRENNVYCEILPCTASIERIKE
                     KNPKGIIFTGGPNSAYLEDSPTISKEIFELGVPILGICYGIQIMSHVLGGVVRKGNKQ
                     EKEYGKTAITYGKSSLFEGITTNSVWMSHTDLIEKVPEGFTIVANTNDCPVAAMENVE
                     RNLYGVQFHPEVEHCLEGDKILTNFLYNICKVKGDWTTDSFIEDKIKELKEKIGDKKA
                     LCALSGGVDSSVAAVLIHKAIGDNLTCIFVDHGLLRKNEGNDVERIFREKFDINLIRV
                     NAEDRFLSKLKGVSEPEAKRKIIGEEFIRVFEEESNKLGKMDFLVQGTIYPDVIESGH
                     GNAATIKSHHNVGGIPEDVDFQEIVEPLRELFKDEVRKIGLELGIEEGLIFRHPFPGP
                     GLGIRVIGDVTKEKCDILREADAVYMDELRKAGLYREIWQAFATLPDVKTVGVMGDER
                     TYAYLVGLRAVTSSDGMTSDWYKMPYDVLERISNRIINEVDGVNRVVYDITSKPPGTI
                     EWE"
     gene            complement(22518..23564)
                     /locus_tag="ACGI5H_000807"
     CDS             complement(22518..23564)
                     /locus_tag="ACGI5H_000807"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009901699.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA];
                     GO_process: GO:0015074 - DNA integration [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HFG9696531.1"
                     /translation="MPAYKDEQRKSWYASFYFTDFDGDRKKKIKRGFKTKKEALEFER
                     EFLNKSKMSTDMSFESLIEEYMHDMSSRLKLSTLETKKYLINFRILPFFKSLKINEIT
                     ATHIRRWQNELLKSDYSQTYIKTINNQLVAVLNYAVKYYNLPSNPAHLAGSIGKKNAD
                     EMNFWTLEEFKKFIEFEKKSEPRLAFEILFWTGLRLGELLALTPKDIFENKISVEKSY
                     IRLNGEDIVSSPKTPKSKRVVPIPHFLYNNIKDYLSKLYDLKDNERIFKFAKSYLSKE
                     LDRCCKLSNVKRIRVHDLRHSHASLLVNMDVNILTIAERLGHEKVETTWNTYSHLYPN
                     KQLEVAQKLDNLNI"
     gene            complement(23641..23856)
                     /locus_tag="ACGI5H_000808"
     CDS             complement(23641..23856)
                     /locus_tag="ACGI5H_000808"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009901700.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HFG9696532.1"
                     /translation="MLKKLRKKKRMTQLELAEKMRRNRSYISKLENQEYKDIGISTIL
                     DLSIALEEDFLELCKYYKLQEIKRRGK"
     gene            24142..24273
                     /locus_tag="ACGI5H_000809"
     CDS             24142..24273
                     /locus_tag="ACGI5H_000809"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9696533.1"
                     /translation="MNENENMSLYVSKLKEVLKNNSEEYKKIRAKINEIYNLNEKKE"
     gene            complement(24290..24691)
                     /locus_tag="ACGI5H_000810"
     CDS             complement(24290..24691)
                     /locus_tag="ACGI5H_000810"
                     /inference="COORDINATES: protein motif:HMM:NF013540.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HFG9696534.1"
                     /translation="MQTLAEIIKEYRSEHNLSLREFSNLCGVSHTYIDKIEKNRDPRN
                     GKAVEPTLDMLEKMSFGLNLTLKELLTKLGKIQPNTQQDDELLKKVNSKEDNEVNELI
                     NRLASLDSDDKNAIKKMIDNAYYKAVNTKKE"
     gene            24877..25068
                     /locus_tag="ACGI5H_000811"
     CDS             24877..25068
                     /locus_tag="ACGI5H_000811"
                     /inference="COORDINATES: protein motif:HMM:NF024835.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HFG9696535.1"
                     /translation="MRKESRISQKKFADKIGISRPYLSRIENGKVNPSLEIAHKISLE
                     TGKTINEIFFDFTVNHSKL"
     gene            25308..25445
                     /locus_tag="ACGI5H_000812"
     CDS             25308..25445
                     /locus_tag="ACGI5H_000812"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9696536.1"
                     /translation="MQREQTTLRIPEDLHKALIDLSSDIGMPITSIIIIACWLYISKI
                     N"
     gene            complement(25431..25742)
                     /locus_tag="ACGI5H_000813"
     CDS             complement(25431..25742)
                     /locus_tag="ACGI5H_000813"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9696537.1"
                     /translation="MTTITVRIYTPLNENLEKISYQTGILKSSLILYAINDIIRNSKV
                     NELQSISYKSDDTVRSTLRIPGVLKELLEKTAKENNLSINSLINNVVHSFCISDWLIY
                     L"
     gene            25863..26033
                     /locus_tag="ACGI5H_000814"
     CDS             25863..26033
                     /locus_tag="ACGI5H_000814"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9696538.1"
                     /translation="MEKVRMTVRLVPKLNQYVQNIAKECGKSKNSIIVDACWEFIEKI
                     KKENKFNVESEE"
     gene            26036..26674
                     /locus_tag="ACGI5H_000815"
     CDS             26036..26674
                     /locus_tag="ACGI5H_000815"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015984876.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Bro-N domain-containing protein"
                     /protein_id="HFG9696539.1"
                     /translation="MNNLQIFEKLEFGQIRMAEIDNKPYFVGKDVAKSLGYKNTNDAI
                     LRHCKGVVKHEGFKINGIKIALITEGDVYRLIVGSNLPNAEKFESWVFDEVLPSIRET
                     GQYQAQQHVITELTGTIGDLKGTIKEYKKLCKITCSKKQQYSKYIKNRLDIDKANKEY
                     NQVKARLFLILGVEKWEDIDFDTSNNLIQIIDDCIRVIKSERPYKQLSYFEN"
     gene            26733..26903
                     /locus_tag="ACGI5H_000816"
     CDS             26733..26903
                     /locus_tag="ACGI5H_000816"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9696540.1"
                     /translation="MKNNISDSRVKYFCKCPYCGFDNEVEVKKGLKPKICCICTKEVE
                     YEKLEQQSTPAK"
     gene            complement(26906..27139)
                     /locus_tag="ACGI5H_000817"
     CDS             complement(26906..27139)
                     /locus_tag="ACGI5H_000817"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9696541.1"
                     /translation="MNIGKITKIEATCFDCGTKVTITESKFREVCDNGLPCPMCKEHI
                     SNSNFIAEQALQYNHAVNKLEKELDSCKNIHIY"
     gene            27208..27405
                     /locus_tag="ACGI5H_000818"
     CDS             27208..27405
                     /locus_tag="ACGI5H_000818"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015984879.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HFG9696542.1"
                     /translation="MAINDNINKILRDRNLKAWKLAKEIGVDSGNLYAILRGENKNPT
                     IDTLIKLADYLDVTLDELVGR"
     gene            27444..27650
                     /locus_tag="ACGI5H_000819"
     CDS             27444..27650
                     /locus_tag="ACGI5H_000819"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009901709.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9696543.1"
                     /translation="MAKAVAKEQLFYRAKDIAKILDVCEATAYKIIGELNKELEKEGW
                     KTFPGRVSVTYFKERYCYKTKKGA"
     gene            27822..28010
                     /locus_tag="ACGI5H_000820"
     CDS             27822..28010
                     /locus_tag="ACGI5H_000820"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894683.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9696544.1"
                     /translation="MRIIYKNKIYKVEQDKVLFRITYYDEQKNNRKFNNNKKVKRSVL
                     TRDIELVNLYLPAHLKIK"
     gene            28026..28238
                     /locus_tag="ACGI5H_000821"
     CDS             28026..28238
                     /locus_tag="ACGI5H_000821"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860994.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9696545.1"
                     /translation="MVFNLEKFKVGNAIRISCERFGFEIDCIVVVATEEELNLAYFDK
                     ERGCIEYQALMPEDLRYDDYILERLG"
     gene            28254..28424
                     /locus_tag="ACGI5H_000822"
     CDS             28254..28424
                     /locus_tag="ACGI5H_000822"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9696546.1"
                     /translation="METAISIAKGQIEGANESIKELKSKENYDKESLRWWEGVKQASE
                     NILEFLEIENKA"
     gene            28506..30458
                     /locus_tag="ACGI5H_000823"
     CDS             28506..30458
                     /locus_tag="ACGI5H_000823"
                     /inference="COORDINATES: protein motif:HMM:NF024867.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_process: GO:0006302 - double-strand break repair
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HFG9696547.1"
                     /translation="MKAILLKSLNIENFKGIKELRIDFNNITNVFGENATGKTSIFDA
                     FTWVMFDKDSKNRSVFEIKPLDKQNKVIRGLVTTVTAVLEVNNKEIKLTKKYEEKWTR
                     KRGESEATFTKNETTYMINDTPIKKSEYVKEVAEIANEEQFKLLTNPYFFSNELNWKK
                     GRELILNVCGDITTEQIIESNKDLTLLITEFEKENNIDKIIKNRKAIKNNLSKEKEEI
                     PVRVNECNKSMYDIDFEEIEAQLKAKKADLEAIEDMLLSGTKANEQILKDKEKIFELK
                     QETQSIKQSASEKGNKKRNELLKEKDELKYNIKNLRNNLVYLERDNELKETLKKRAIE
                     KTTNLRDKWTKKSQETLDLSVIQTECPTCKRPLDLEDIEEKKKEMLDNFNLNKAKELK
                     EIAELGKSKNDDVELFNTEIERLKVDINKTLEEIQEKAVLLDKIKKELESTKSTEIYS
                     ADEEKRLTEISAEIKELEEKINNKDADKNIDELKENKKKLTSEIELLNKELAKRDINK
                     ELLDRKEQLLEKEKALGIELAHQEKILNLCELFIKTKVSLLESNISSKFKNVTFKLFK
                     EQINGGIEETCEALINGVPFSNANTAGQINGGLDIINTLSNHFEVKMPIFVDNRESVN
                     NLIDIDSQVINLIVSNDNPLKIEGVN"
     gene            30459..31376
                     /locus_tag="ACGI5H_000824"
     CDS             30459..31376
                     /locus_tag="ACGI5H_000824"
                     /inference="COORDINATES: protein motif:HMM:NF015776.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase RecT"
                     /protein_id="HFG9696548.1"
                     /translation="MAERNITDVVLNRVNELKDSGELVIPPTYSAVNALKSAYLILQE
                     TLDKSYKPVLETCTPISIINSLLNMVIQGLSPAKKQCYFVAYGNKLQLMRSYMGTIAV
                     TKRLSNIKDIKAYCIYEGDKFKVKYNKENAVLEIGEYEPAFENIDIGKIKGAFAVIVG
                     NEGILHTEIMTFTQIERAWLQGVGYSNPKNKVHDNFTEEMAKKTVINRACKMYANTSD
                     DSDLLIGAFNETDRVITSEEIAKDTDKEVEKEISQNANIKSLEMPSQVDNTIFTQTKE
                     KVAINIDEDKPNLAEFEEAIQVELDTPPF"
     gene            31421..32089
                     /locus_tag="ACGI5H_000825"
     CDS             31421..32089
                     /locus_tag="ACGI5H_000825"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018592586.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HFG9696549.1"
                     /translation="MLQLENETLILECGVSYKEILKGLDFSLENVVGCLVTHEHKDHS
                     KAITELTNNGIDVYSSKGTLEALKIENHRTKIIESEKLFKIGNFKIVPFNTKHDAVEP
                     LGFLINHSSFGNLLFITDSYYCEYNFNNLNHIMIECNYSKDLLDNNKDKIYLRNRIVK
                     SHFELSNVINFLKVNDLSNIKTITLLHLSEDNSDKDLFIREIEKNVGVPVIVAEKGLE
                     IYLD"
     gene            32100..32993
                     /locus_tag="ACGI5H_000826"
     CDS             32100..32993
                     /locus_tag="ACGI5H_000826"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894692.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0006269 - DNA replication, synthesis of
                     primer [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DnaD domain protein"
                     /protein_id="HFG9696550.1"
                     /translation="MAKYRILQANFWDDGFVLDLTPEEKYFYNYLLTNGRASQCGCYE
                     LPYKIMEMQTGYNRETVEKLIKRFIEYGKIKYDSTTKEILIINWSKHNFSKSPKVRTC
                     ILKEVESIKNKEFQQYMYRVCIDYGYPIDTVSIDYGEKEKEKQKEKEKQKEKEKQKEK
                     VEPLICEEQEKNELKEFKKLYEENIGVVYPVTAEWLIEISSDVDIRLFKSAIEICAEK
                     MNMNIAYLKGILKKWKDANITTYEQLESYRLQQENKKAKKVVNGQLSKNKFANFEQTF
                     TKYTENELDNIIKKSQDAKFK"
     gene            33051..33398
                     /locus_tag="ACGI5H_000827"
     CDS             33051..33398
                     /locus_tag="ACGI5H_000827"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016056367.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9696551.1"
                     /translation="MGKIWMDAGTFLETKDIGDIECNLREMINKNKQKNLIGRINSKG
                     QGRKSKKVECTNIITGESKIFVSAVEASEYLYFTELHITRLARTGKTTKNGWKVRYIE
                     EVSNGISKCGTSN"
     gene            33367..33504
                     /locus_tag="ACGI5H_000828"
     CDS             33367..33504
                     /locus_tag="ACGI5H_000828"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009901524.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9696552.1"
                     /translation="MVLANVEQVIKLAEKILSKKKCSVNKAIDIAIKILNRYEYEGMI
                     K"
     gene            33501..33950
                     /locus_tag="ACGI5H_000829"
     CDS             33501..33950
                     /locus_tag="ACGI5H_000829"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9696553.1"
                     /translation="MSLIEYRGYDFENKKWIYSKTIMWSNAVDCLLMLKEDFKWRKVC
                     NVGICSEEWAGNNQEIFEGDILKENYNPHNRSSYGIVKRDFNSIKLYLEWHYLKKFEG
                     EWIEIIDKTEIYHSRGYKVIGNEYENLEEVRKEFLERKEMLENERLS"
     gene            33934..34059
                     /locus_tag="ACGI5H_000830"
     CDS             33934..34059
                     /locus_tag="ACGI5H_000830"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861006.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9696554.1"
                     /translation="MNVLASLILIVGSFIAGRVYEYRLNLKEFENYDNIGGFKNE"
     gene            34052..34210
                     /locus_tag="ACGI5H_000831"
     CDS             34052..34210
                     /locus_tag="ACGI5H_000831"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894708.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9696555.1"
                     /translation="MNDRLEMINASVNYIQMICESSNIAIIAEHDRVRILDLETKEKY
                     DLLRSEGD"
     gene            34214..34537
                     /locus_tag="ACGI5H_000832"
     CDS             34214..34537
                     /locus_tag="ACGI5H_000832"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9696556.1"
                     /translation="MSKVIQCDFCKEIFEKYNGECIELYKKDCSKGVLGIDKHICPTC
                     YEKFIEGKIEKVENAKRFKDKLIDFLVEHEVCDCCACDCVFDSNDEKKCKAGIREWVE
                     SEVEE"
     gene            34539..34838
                     /locus_tag="ACGI5H_000833"
     CDS             34539..34838
                     /locus_tag="ACGI5H_000833"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9696557.1"
                     /translation="MAKLIVSIPLTKYLKDITKEWGETYITKTYGGHVYLSDEAPGEV
                     FKKEDDLNYIEFNDSDIVMRLPKEVHQHINLKKGCNKNLKDVLKEIKKIEEKTNI"
     gene            34946..35842
                     /locus_tag="ACGI5H_000834"
     CDS             34946..35842
                     /locus_tag="ACGI5H_000834"
                     /EC_number="2.1.1.37"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861009.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003886 - DNA
                     (cytosine-5-)-methyltransferase activity [Evidence IEA];
                     GO_function: GO:0008168 - methyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:1904047 - S-adenosyl-L-methionine binding
                     [Evidence IEA];
                     GO_process: GO:0006304 - DNA modification [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA cytosine methyltransferase"
                     /protein_id="HFG9696558.1"
                     /translation="MLTFLDLFAGIGGFRLGMEKAGHKCLGHCEYDKFANLSYNAMHK
                     PKEDEWFERDIREIRTENIPRADVWCFGFPCQDISVAGKQFGFKGRRSSLFFAVTKLI
                     RELKEEDRPKYLLIENVKNLLSVNGGFDFLKVLIELDEIGYDAEWQVLNSKNFGVPQN
                     RERIFVVGHFRGRSTRKVFPIERKSRKNLEQLNNPTHSTSGVLVNAVLTPDRVNKRQN
                     GRRIKESGEPMFTLTAQDKHGILKNGDIRRLTPKECFRLQGFPDKYYERAASVCSDSQ
                     LYKQAGNAVTANVVYEIAKRMG"
     gene            35921..36142
                     /locus_tag="ACGI5H_000835"
     CDS             35921..36142
                     /locus_tag="ACGI5H_000835"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018112749.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9696559.1"
                     /translation="MSKYVLRWQKGLLLDERKINYSCGSKEMLKQKAELLAKDDKILL
                     VTIDKVEEVIKDTRSQKMAEYYCDGGIEI"
     gene            36139..37143
                     /locus_tag="ACGI5H_000836"
     CDS             36139..37143
                     /locus_tag="ACGI5H_000836"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729497.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoid-associated protein"
                     /protein_id="HFG9696560.1"
                     /translation="MIIHKFIIHVLDKNSDTPILNDFEGRVSQDIEAFFQKKISKVSR
                     DNDIRTVVFNDYSNNLIKKCCEQIIYDESSFLNNSKEIAAYLFDVMKLNAILESCDLA
                     ICLYSQKDEKKVAILKLDYNNSYTHSISFEEDKFNIQMSKNEINIQETKTVKIAALVG
                     LSGMNDEYHLKVLDKDAEKEEANSKFVTEFLNATKVKDDKYRTKKFKDTVENWITNVL
                     GNDIKQAEDIRSILNYTLKEKHEIDIKDFVDKSIKDDELKNSFKEHMEEKGLDESFSI
                     DKKWVEKKLKKRNIKTDNGFEIKGNLTDFEDPMKYTVRQNQNGSIDIIIKNVNFYNEK
                     "
     gene            37154..37444
                     /locus_tag="ACGI5H_000837"
     CDS             37154..37444
                     /locus_tag="ACGI5H_000837"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9696561.1"
                     /translation="MENKDNFVLNKLGPASKVMKKVEIDEKEIKSYLKELKECEEVKV
                     FIIRKDGIEIPIVFKDGNMNEWLRKEIEISFDRFKDEIAQVKKALIKVTGEN"
     gene            37464..37631
                     /locus_tag="ACGI5H_000838"
     CDS             37464..37631
                     /locus_tag="ACGI5H_000838"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016056370.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9696562.1"
                     /translation="MTNKEMCKSNNLDEREVCKEFGKEICGSCINDRVDCESKDCDIA
                     YENWLEKNTER"
     gene            37717..38058
                     /locus_tag="ACGI5H_000839"
     CDS             37717..38058
                     /locus_tag="ACGI5H_000839"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861739.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor-like protein"
                     /protein_id="HFG9696563.1"
                     /translation="MANIYCENYNCKNYFEDMCMLERIEINNLKVCESYIEGKNELYK
                     LENGYTIHPKDLKMVKSKDYSVEVTHIPTGITVKCRSTNSILKNKNKCLEVLEEELIK
                     INSHLELEDLN"
     gene            38184..38591
                     /locus_tag="ACGI5H_000840"
     CDS             38184..38591
                     /locus_tag="ACGI5H_000840"
                     /EC_number="3.1.21.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894734.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000287 - magnesium ion binding [Evidence
                     IEA];
                     GO_function: GO:0000400 - four-way junction DNA binding
                     [Evidence IEA];
                     GO_function: GO:0008821 - crossover junction DNA
                     endonuclease activity [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="RusA family crossover junction
                     endodeoxyribonuclease"
                     /protein_id="HFG9696564.1"
                     /translation="MKVFLVIDGEPVGKERPRMNTYAKRTYTPNKTKNYEDLIKWLYQ
                     SKVKYYFEGYIKMTLRCYYSIAKSNSKKVKEQKRNNVLRPSKKPDIDNVIKVVADSLN
                     EIAYKDDTQIVEVVASKYYSDKPRVEVILEDVI"
     gene            38693..39547
                     /locus_tag="ACGI5H_000841"
     CDS             38693..39547
                     /locus_tag="ACGI5H_000841"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015994384.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ORF6C domain-containing protein"
                     /protein_id="HFG9696565.1"
                     /translation="MNENINKEITVLGTLEIEGMKFHNIEGGFGEHKKAMLVKDIAEI
                     HNRELKHINELINNNIKRFKTNIDIIDLKVSRSERLGDLKANPFEGLGYEDVGYSKQS
                     FNQSRNIYLLSERGYSKLLKILEDDKAWEQYEKIVDGYFSMRKELNNPLLSASKELQA
                     IFMLDKKQEVLETKIENVNEKLENFMDDAPLFNIECECIVKEVKRVATKSLGGHGSKA
                     YKNKSLRGKVYSDIYHQIKREFGVDSYKAIKRCQLDKVLEIVNNYKLPIVFEEEIRLL
                     NSQLSIVS"
     gene            39699..40205
                     /locus_tag="ACGI5H_000842"
     CDS             39699..40205
                     /locus_tag="ACGI5H_000842"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016056376.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9696566.1"
                     /translation="MSKTKKEFFNATKKQLSNYKQLSANIIKLKNEIQMLKDNSVGDL
                     MKGISYDSVKTGKTNKTSNMIEDAIVNVSDLITEKEIELYEAEIIKSTIDLAIRNLKP
                     IHRQIIELKYIDGLMWQEMVDIVHLEERQLSVRASQAISSISIALFGKKALIEQEPLF
                     ELLDYKLN"
     gene            40958..41131
                     /locus_tag="ACGI5H_000843"
     CDS             40958..41131
                     /locus_tag="ACGI5H_000843"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894739.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9696567.1"
                     /translation="MATKSILKNVDVRKKAFGRNLVSALENAKNKQEKEVVLSKKCSE
                     VPKDKIKDIFGRF"
     gene            41131..41742
                     /locus_tag="ACGI5H_000844"
     CDS             41131..41742
                     /locus_tag="ACGI5H_000844"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894741.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetyltransferase"
                     /protein_id="HFG9696568.1"
                     /translation="MSGYLIVNLSNMLGELEEEEVKKILSSFSCPLNKDVEDFLKNKA
                     IEFSKQGLASTHLVLTSYKGKPVIVGYFTLANKYFTIKRKTLTNSLARKVVKFGQYNE
                     ELRRYIIGAPLIGQIGKNYSNNYNKLIKGDELLKIACDKIKAVQLDMGGKIVYLECED
                     KPKLIEFYKDNGFVDFGKRSLDKDETDSLDGDYLVQMLKYLKK"
     gene            41819..42445
                     /locus_tag="ACGI5H_000845"
     CDS             41819..42445
                     /locus_tag="ACGI5H_000845"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9696569.1"
                     /translation="MKKITKLILCSLLVISIASPLQVEAKTTHHSSSHVSIHKSSTKS
                     KSSRPKITKTKKATKTYRTNKSIKKKIKLKKQVNKKTQVPNKQAARKDKKTTTYNYYN
                     SYNSNRYYTTSSSGLSFWDCYMLGHLFNNNNKVSEQDIARELQKQGYSKQETDNILRK
                     ANQNQAKKEEKKKRVMMLIFSVLGALFIIGLGLIIFIKRESKGCNKSM"
     gene            42518..43207
                     /gene="terS"
                     /locus_tag="ACGI5H_000846"
     CDS             42518..43207
                     /gene="terS"
                     /locus_tag="ACGI5H_000846"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861025.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage terminase small subunit"
                     /protein_id="HFG9696570.1"
                     /translation="MNEKADLAHEDYLKGLKYKEIAEKHNVSLSTVKSWATRYWKQKG
                     CNQSKKVATKKRGAPIGNKNATGPPGNKNAEKFGFFSKYLPEETRELMQEISIKDKFD
                     ILWEQITIQYAAIIRAQKIMYVKDKEEMIKELKKHESTENGEKIEYEFQFAWDRQASF
                     LNAQSRAMSELRSLIKQYDEMIHKDWNLATEEQKTRVEKLKCEVDNLSKDDIGDDELK
                     ISVDYGDRNDS"
     gene            43197..44438
                     /locus_tag="ACGI5H_000847"
     CDS             43197..44438
                     /locus_tag="ACGI5H_000847"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888830.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PBSX family phage terminase large subunit"
                     /protein_id="HFG9696571.1"
                     /translation="MIVRVNFNPDFKEANFTKKRYRAMKGSAGSGKSVNVAQDYILKL
                     GDKKYQGANLLVVRKSEATHKYSTYAELTGAINRIYGKQADKYWKTTLNPLEIKSKVT
                     GNSIIFRGVNDAKQREKLKSINFSKGKLTWVWCEEATELMESDIDILDDRLRGILTNP
                     NLYYQMTFTFNPVSSTHWIKRKYFDYKNDDIFTHHSTYLQNRFIDEAYYRRMQMRKEQ
                     DPEGYKVYGLGEWGETGGAILKNYVIHEFPTEFEYFDNMRLSQDFGFNHANVVLRIGF
                     KDGELYICNEIYVHEMDTSEIIKIANSKGLEKNIFMYCDSAEPDRIKMWKSAGYKAKG
                     VKKGPGSVKAQIDYLKQLRIHVHPSCTNTIKEIQQWKWKQDERTGLYLDEPVEFMDDA
                     MAALRYSIDNKLKNNGISFLK"
     gene            44525..45883
                     /locus_tag="ACGI5H_000848"
     CDS             44525..45883
                     /locus_tag="ACGI5H_000848"
                     /inference="COORDINATES: protein motif:HMM:TIGR01538.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0046798 - viral portal complex [Evidence
                     IEA];
                     GO_function: GO:0005198 - structural molecule activity
                     [Evidence IEA];
                     GO_process: GO:0051027 - DNA transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phage portal protein"
                     /protein_id="HFG9696572.1"
                     /translation="MEHYILKHRPEKYKQGEEYYYGNADINNKRRYYLLDGAKVDDFT
                     KVNNKAINNYHKLLVDQKVGYSVGNPIVFNADDDNLTKLLNDLLGEEFDDTITELYLN
                     ASNKGVEWLHPYINRKGEFKYVIIPAEEAIPIWDSKRQRELVAFIRFYYIEDIDGNKI
                     KRVEYYTENDVTYFIERGNSFIQEFLYDEYGKMTDIQEGHFRINNKEQGWGKVPFIPF
                     KNNEKCVSDLTFYKSLIDIYDNNISTLADNLDEIQEVIYVLKEYPGTSLQEFIDNIRY
                     YKSIKVDGGGGVDKLEINIPVEAKKELLDRLEKNIIIFGQGVNPESQNTGDKSGVALK
                     FLYSLLDLKCSKTEKKFKKAIRELLWFVCEYLKISGNKSYDYKTVQITFNHSMIINEA
                     EKIDMAAKSTGIVSDETIVSNHPWVEDVNDELERLKKQEDTQKEYDDLIPNNQDGVID
                     ET"
     gene            45873..47234
                     /locus_tag="ACGI5H_000849"
     CDS             45873..47234
                     /locus_tag="ACGI5H_000849"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893134.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0044423 - virion component [Evidence
                     IEA];
                     GO_process: GO:0016032 - viral process [Evidence IEA];
                     GO_process: GO:0019068 - virion assembly [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="minor capsid protein"
                     /protein_id="HFG9696573.1"
                     /translation="MKHKDYWRKRFEQLEEAQNNKSIKYYLELEKQYKLAMSNIEKDI
                     LIWYNRFTENEGISLLEAKKLLNTRELEEFKWSVEEYIKYGKENAINQKWMKELENAS
                     ARVHITRLEALKLQIQQQVEVLYGNELDGIDKLMRDIYTSGYYHTAFNVQQGVNVGWS
                     LMSLDTNRINKVISKPWTSDGLNFSERIWGKHRPALINELHTKLTQSIIRGENPKVLV
                     NEFSKKFNVSKSQAKNLIMTESAFFASASRKDCFNDLDVEKYEIIATLDLKTSNICRE
                     LDGKVFDMKDYQVGITAPPFHCHCRTTTAPWFEDEEGYRAARDENGKTYYVPSGMKYK
                     EWYEKTFITDKKDDILSNKSWLKADFPTEKKFKKHVEKHLNEYGNITAEEYLSTARNL
                     LSEQLSNDVEGFLSKDNFLFKYRKSTNDFAVGRADGKISTLFKPKEGYNYWLEQIKEY
                     KEV"
     gene            47237..47398
                     /locus_tag="ACGI5H_000850"
     CDS             47237..47398
                     /locus_tag="ACGI5H_000850"
                     /inference="COORDINATES: protein motif:HMM:NF025569.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPCC family cysteine-rich protein"
                     /protein_id="HFG9696574.1"
                     /translation="MNCPVCGKDVDVFDICDNCNWQNSGPKETNYKGPNKMSLKEAKE
                     AYEKGKKVI"
     gene            47730..48122
                     /locus_tag="ACGI5H_000851"
     CDS             47730..48122
                     /locus_tag="ACGI5H_000851"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9696575.1"
                     /translation="MAKFKKKSEEVEAFKWILGSPNTPIWFYQAFEKGTIWLDESLNS
                     VNRKGEVKKTICIKYKNGVIRATNGDWIIKDSEGKIYSCTCDEFEKYYKDLDNETKIS
                     NGGLECLREIALKDVNFKFELTGIKEEK"
     gene            48123..48320
                     /locus_tag="ACGI5H_000852"
     CDS             48123..48320
                     /locus_tag="ACGI5H_000852"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015981492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9696576.1"
                     /translation="MFYLLLQVISICLSITVFMYVTGNIVFKIYLKSLRKEYESNIHE
                     VSDEILKRIRKELNKSLDESL"
     gene            48363..48593
                     /locus_tag="ACGI5H_000853"
     CDS             48363..48593
                     /locus_tag="ACGI5H_000853"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9696577.1"
                     /translation="MKEYMIWFKSGNSISGIVDEDVADKLMQDFMEADSDCKDLKVYL
                     DEDGTTVIDLSQIEAISINNCNENNNIGFSKS"
     gene            48638..49201
                     /locus_tag="ACGI5H_000854"
     CDS             48638..49201
                     /locus_tag="ACGI5H_000854"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728455.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0019069 - viral capsid assembly [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phage scaffolding protein"
                     /protein_id="HFG9696578.1"
                     /translation="MDWLKELLEGIKVEDNKIDVASLQKSIEKKIKETTITKEDYTNL
                     ETQLNTANETIKKFEGGMTKEDVENLKTTYETDKKTLEETYKKEIEEKDFNYWLNDAF
                     KSIKCRDEIALKAHLDIEALRNSKDRQKAFEEQINPLKQDKDYLFNATLEGEEPKIDT
                     ITPGQEPKINDFGFNFTGVRPHENNNK"
     gene            49213..50112
                     /locus_tag="ACGI5H_000855"
     CDS             49213..50112
                     /locus_tag="ACGI5H_000855"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861029.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="capsid protein"
                     /protein_id="HFG9696579.1"
                     /translation="MAALNYAKEYSNVLAQAYPYTLNFGDLYATPNNGRYRWTGSKTI
                     EIPTISTTGRVDSNRDTIAVAQRNYDNAWEPKVLTNQRKWSTLVHPADINQTNYVASI
                     GNITKVYNEEQKFPEMDAYCISKIYADWTALGNTADTTVLTTTNVLEVFDKLMEKMTE
                     ARVPENGRILYVTPVVNTLIKNAKEIQRTVNIKDAGTSLNRQTTDIDTVKIIKVPSNL
                     MKTAYDFTTGWKVGAGAKQIFMSLVHPSAIITPVSYQFSKLDEPTAVTEGKYFYFEES
                     FEDVFILNKKADAIQFVVEGAGA"
     gene            50112..50345
                     /locus_tag="ACGI5H_000856"
     CDS             50112..50345
                     /locus_tag="ACGI5H_000856"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896624.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9696580.1"
                     /translation="MAQVRKLNRILTIEECKIDDFLEMGYDLIDETGKAVKYGKSLNV
                     KDLIAENNILRSKVESLEEENKQLKEKNKLTKK"
     gene            50355..50756
                     /locus_tag="ACGI5H_000857"
     CDS             50355..50756
                     /locus_tag="ACGI5H_000857"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9696581.1"
                     /translation="MGNNIIDDIEKRLESFGYILKDGDKWLIDFVREKIENIIKLDCN
                     IKTMPIELKEIEVDMIVGEFLFTKKNMGQLDIESINFEAVEKSISEGDTKVDFAIGSG
                     SQTPEQRFDSLVAYLTTYGKNNILTFRCLRW"
     gene            50750..51097
                     /locus_tag="ACGI5H_000858"
     CDS             50750..51097
                     /locus_tag="ACGI5H_000858"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015984843.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9696582.1"
                     /translation="MVSKTRKAIEMLYRDKCTIVEYQPIKDPVTKRTNNKEVIVLENQ
                     PCKLSYKNIVSATEGKVAKLEQTIKLFISPDIEIKAGSKLIINDKEYVRSGESAIYPN
                     HQEIILELFKDKA"
     gene            51097..51522
                     /locus_tag="ACGI5H_000859"
     CDS             51097..51522
                     /locus_tag="ACGI5H_000859"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896626.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HK97 gp10 family phage protein"
                     /protein_id="HFG9696583.1"
                     /translation="MARWGSVDFREFKRVCKKMEELTKIDLDKFCKDAARELAARLLG
                     KVIRRTPVDTGFLRQGWNGVAYARSLPVYKQGNNYIIEVVNPTTYASYVEYGHRTKDG
                     KGWVKGQHFLTISEMELQSQVDKIIEKKLLILLKGVFDA"
     gene            51515..51952
                     /locus_tag="ACGI5H_000860"
     CDS             51515..51952
                     /locus_tag="ACGI5H_000860"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728452.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF6838 family protein"
                     /protein_id="HFG9696584.1"
                     /translation="MLNNIIDGISIKLDKTFGESYTIYSEDVEQGINEPCFFIVPLNP
                     SKTPYPSGRELKKNSFDVHYFPRSEAKNFEINEIAEMLLEELEYIEIDGDLVRGTNMN
                     FEIIDNVLHFFVDYNYFTIKNNDTNKMDTVELFGGLKRGDNFE"
     gene            51936..52121
                     /locus_tag="ACGI5H_000861"
     CDS             51936..52121
                     /locus_tag="ACGI5H_000861"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429847.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9696585.1"
                     /translation="MIILNKTLSKEDDYKFTKEQIVNSKKYVNRKDLLNAILKENELY
                     SFSEVEEIINKFMKGVS"
     gene            52122..53432
                     /locus_tag="ACGI5H_000862"
     CDS             52122..53432
                     /locus_tag="ACGI5H_000862"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728450.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail sheath family protein"
                     /protein_id="HFG9696586.1"
                     /translation="MALGGGTFVTQNKILPGSYINFISAKRATSSLSDRGIVAIPLEL
                     DWGIDEDVFQVTSDDFEKYSVKYFGYDYTHEKLKGLRDLFKNIRLGYFYKLNKGVKAS
                     CTIATAKYSGIRGNDLKVTVTTNIDDNAKFDVVTLLDNKKVDTQIAKVITDLQDNDYI
                     TWKKDATLEASAGLVFTGGTNGEAVTGAEYQAFLDKIESYSFNALGCLATTTEIKSLF
                     VEFTKRMRDKVGAKFQTVLYKKSDADYEGVVSVENKIKDKDLVESSLIYWATGAIAGC
                     DINKSNTNKKYDGEFDVGVNYTQIQLEEALKSGKFIFHKVGDEVHVLEDINTFVSFTD
                     DKNDDFSSNQSVRVLDQIANDIATLFNTKYLGEVPNDKSGRISFWNDVVKHHEQLQNM
                     RAIEDFKADDVSVEPGSDKKTVVVSDAVKVISAMSKLYMTVSVS"
     gene            53454..53924
                     /locus_tag="ACGI5H_000863"
     CDS             53454..53924
                     /locus_tag="ACGI5H_000863"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728449.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail tube protein"
                     /protein_id="HFG9696587.1"
                     /translation="MAQQIKARDTISASKAECFVTIKGKRYNFMQAINLEAKMEKNKS
                     EIPILGSTTKGNKSTGSKYSGNATFYYNTSIFRELLYEYKETGEDIYFDIQITNEDPT
                     SSVGRQTIILEDCNMDSGIIAKFDADGEYLDEDMDFTFENWKLVEKFNIANGME"
     gene            53977..54234
                     /locus_tag="ACGI5H_000864"
     CDS             53977..54234
                     /locus_tag="ACGI5H_000864"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009901462.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9696588.1"
                     /translation="MIKIKDKYEIKDSISFDYSNKRPLEERVSEMYKKAGKYLIDISD
                     KLATDTIDGSSLKPIIIKFEINEAGVATIEKQTKYLVMEVE"
     gene            54239..54679
                     /locus_tag="ACGI5H_000865"
     CDS             54239..54679
                     /locus_tag="ACGI5H_000865"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009901463.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage portal protein"
                     /protein_id="HFG9696589.1"
                     /translation="MGDLNAFLSQNAIKVENRKYVASERFIGEDGKAIEWELKAIDSD
                     RDRQLRKDSTIRVPILNKKGKATGQYTSETDFNTYTLKLCVETIVFPDLHDAELQNSY
                     GVMGAEELLTTMLTPGEYTDLSSEVGEVNGFDRTFEDKVEEAKN"
     gene            54941..55732
                     /locus_tag="ACGI5H_000866"
     CDS             54941..55732
                     /locus_tag="ACGI5H_000866"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888848.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SHOCT domain-containing protein"
                     /protein_id="HFG9696590.1"
                     /translation="MGLFSKKNKKPCCICGSEKGLMPSIEGENFCTACNCKYIDFSEN
                     ILKVTSIMKMMSNSEGMKKFIEVEKKNLKLLEKFTETKSINSSISFDEEQNLLKISYK
                     NRNQILVEKIIKFDDILEFELLEDGETIVKGGLGRAITGGVLFGGTGAVVGGITGKKT
                     SRKVVEIFKIKITVKDINNPIEYINLINSKVKTNSSIYQKAFSDAQEILSILSIITKY
                     NVMEDKKKSISSSTADEILKYKNLLDMEAITQEEFDAKKKELLNL"
     gene            55799..58141
                     /locus_tag="ACGI5H_000867"
     CDS             55799..58141
                     /locus_tag="ACGI5H_000867"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009901478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tape measure protein"
                     /protein_id="HFG9696591.1"
                     /translation="MATIQTSIRIFDGMTPAFRHMNNAMNIVLSSFEQLQRTSSNAID
                     ANSIRTAREELARAEAGFDRLEQQIRESDNQQRRLNEDINKGASSTDRLVGSAKKLAA
                     TYLGIRTLGGLGNLSDQMTSTNARLSMINDGQLSDGGLNKMIFQSAERSRASYLDTAK
                     IVSRIGMNAGKAFSSTKEIVGFAEQLNKKFVIAGASTEEMNSALLQLTQGLSSGVLRG
                     EELNAVFESAPNIIQSIADYLDVDIGKIRGMASEGMLTADIVKNSLLAAAEQTNAEFE
                     KMPYTLGQIFTSVKNNAVMVFGAIQKKIEDTVSSRGFRTFITDVKDSLYVLGAVGFNV
                     FSGFINLLSSPAFQNFFNVMIVGTSLVVQGLGWIITQALSVANVFSRNWSIISPIILG
                     VVSAISTYIIALGIMQAVTIAGTVANWMSWTSEVIRQRGILGTARALAIGKAEQWGFN
                     AAIYACPIFWIVLGIIAVISAVFILVAVYNHFAGTSISAISLIVGAWYWLCAVVYNVI
                     VGIVNAINICVVEIANIFRTGLYAVQCFFIDMANAGLKAGVNLDKAFDKFATNLANGI
                     IKAVNIAVKGLNWLVQQINKIPGIDLPQMKEFQKVNTVIGTKTTFKPIQKPPEPKAWK
                     PELVEYKNLKSEFIKGYDVGHQLQNKFKDTFDISKIAEKAKKDLGLDDLWDKKYGLGD
                     GLGSAGLNSPLSDAAKGAKDTAGNTAKMAKTMDKSQEDLKYLRDIAEQETINRFTGVN
                     IKIDMNNTNNISKDADVDGIVNVLTEKLNDAMVVSAEGIV"
     gene            58157..58858
                     /locus_tag="ACGI5H_000868"
     CDS             58157..58858
                     /locus_tag="ACGI5H_000868"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429864.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysM peptidoglycan-binding domain-containing
                     protein"
                     /protein_id="HFG9696592.1"
                     /translation="MAYDFYLDGVQLPIPPPKLEIKVTNKNKTVDLINTGEVNILKKE
                     GLSEISFEAEFTHNKLPFYRGTFRDVQFFLSKLELLKTDCKPFQFIVSREMGGKVLFN
                     TNMKVSLEEYNIVEDADNGSDVKVAIKLKQYRDYSTKKLVPATPEKTNYGRTPTPVMK
                     PKEFRPDSSNKPNGKTYTVKAGDSLWSICQKQLGNGSLYKKVYELNKTMMDKANKGKK
                     VPKYTIYKGQVLKLG"
     gene            58851..60824
                     /locus_tag="ACGI5H_000869"
     CDS             58851..60824
                     /locus_tag="ACGI5H_000869"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861038.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NlpC/P60 family protein"
                     /protein_id="HFG9696593.1"
                     /translation="MADELVLANDRDVRLVIAHWEDFYEPVVLDGITWEIERRGTPSK
                     LEFTIVMDDILEFCEGNSVRLYYKGIGIFYGYIFQKKRDKENHIKIVAYDQLRYFKNK
                     DTYVYSNKTASELVKMLAKDFNLKYNVIEDTKYKISRIEENKTLFDMILTALDDTLRE
                     KKEMYVLYDEFGRITLKNVASMKLDTVMNNDVIEDFDYNSSIDSDTYTKIKLVRDNEE
                     SGKRDVYIAQDSTHMRSWGILQLFDTVDKNMSEAEIKQKCDILLKLYNKKTKSLSLKN
                     VLGDIRVRAGCLVPVFLDLGDIDLQNYMLVEKVKHTFENNSHFMDLTLVDGDEFASYS
                     SSSYSSGNTNNKDEKKNGPAQSTTSKEDNDMINKLNKVFKNKLSNTGSIFVKYSNAYK
                     VNAALMAAISIHETGNGSSSLCKNKNNFFGMKGMSFGSVDEGIKRGISNLSRNYIHMG
                     RKTLESIRDKYAPLYDSPLNKHWVPGVNKFYKQITGNAYSSNSAGTGVRSNEEAEKNL
                     KDITYQVQNSNNANTSTNNNSKVNKVIQEAKNQLGKPYKWGGNGPKSFDCSGLMVWAF
                     KRGAGINLKRVSADQSNDSRGKLLCNINDVKAGDLVFFAYNQGKGNVHHVGLCIGNDK
                     FIHSPNTGDVVKISSLSGRQKQKHDFARARRFF"
     gene            60838..61098
                     /locus_tag="ACGI5H_000870"
     CDS             60838..61098
                     /locus_tag="ACGI5H_000870"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009901352.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2577 domain-containing protein"
                     /protein_id="HFG9696594.1"
                     /translation="MSQDLLQIIKKAAMDAVETSNPMQIAFGTIESVNPLVVKIEQKA
                     SFEESFLIQTDTFKRYTDKKIGDKLVLIRMQGGQQYLILDRM"
     gene            61103..61522
                     /locus_tag="ACGI5H_000871"
     CDS             61103..61522
                     /locus_tag="ACGI5H_000871"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009901339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2634 domain-containing protein"
                     /protein_id="HFG9696595.1"
                     /translation="MLPTDNIDYDIEDVSIINFDVRQEPSKTFKLNIEKSKIDGICDD
                     VEALKQTIFLILNTERYQHLIYSWNYGVELNDLIGEPISFVIPELERRIKEALIQDDR
                     IENVDNFEFENIKGKVNCKFMVHTKYGNIKAERVVSV"
     gene            61522..62571
                     /locus_tag="ACGI5H_000872"
     CDS             61522..62571
                     /locus_tag="ACGI5H_000872"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728467.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="baseplate J/gp47 family protein"
                     /protein_id="HFG9696596.1"
                     /translation="MFEFMTFENIIKRMLDSVPSTLDKREGSIIYNALAPVAIELSET
                     YIAMDELLDQTFVDTASYYYLEKRCKERGITPLEATNTIAKGVFNIDIPLDSRFNLGE
                     YNYVAIERISECIYKMKCETAGPIFELGQLIPIEYIDKLETAELTEILINGEDEESED
                     SLRQRYYDSLNSQSFGGNMQNYKDEVNKIQDVGGVKVYPVWDGGGTVKLVIINSNFKV
                     PSEDLVNLVQEEIDPIGHQGQGLGLAPIGHRVTVEGVTSTTINISAEITYKSGYTWEN
                     IKTIAEEAVDDYLNELNMSWEDEENLIVRISQIETRLLSIDGVLDIANTMINSIASNL
                     NVDKDSIVLRGEVVG"
     gene            62564..63181
                     /locus_tag="ACGI5H_000873"
     CDS             62564..63181
                     /locus_tag="ACGI5H_000873"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861041.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YmfQ family protein"
                     /protein_id="HFG9696597.1"
                     /translation="MDKEINLINYLPQILRDKEEYIKVFNVENKEIKTLHEKLNDLSN
                     DQFLEDLTPSGIKRWEKIMSITPKSNESLEDRRFRIFSKYISKLPYSERFLRNWLDNV
                     VGEGNYELTINNATYNIHLESDARNQDWFEEVHSFVSNIKPCNMTLDYTRVLISKDNY
                     MNFGITTLMGQEITIYPWSPPDIETYGEIDVLTGNGVGYQEITIF"
     gene            63193..64185
                     /locus_tag="ACGI5H_000874"
     CDS             63193..64185
                     /locus_tag="ACGI5H_000874"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015984856.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HFG9696598.1"
                     /translation="MAIDKSYYTIITDVGKAKIANASVTGNKVGFVKIQLGDGGGSEY
                     TPTESQTALKNVVWEGNIGNTTTDETAPNCIILESLIPSSVGGFMIREIGYLDDENNL
                     IAISKYKECYKPSIEQGAVVDMKVKTVLIVSNVNNIELKIDPTIIFATLKDIQDLETK
                     IGTVNTKIDTTKTELNTRIDTENEKQNIKIDQLIAGGSNVSHTHIIEIDDWILNNETN
                     MYEVTINHPLLTKRILIALYDEIGEALTPNARAIDDNSILVRNEENIKMYVYLINGNA
                     ETHFINATVDDNRVSEMTTYSSKKIEDRLINIEEKVNGGLSSIATSVNELITYC"
     gene            64202..>64552
                     /locus_tag="ACGI5H_000875"
     CDS             64202..>64552
                     /locus_tag="ACGI5H_000875"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018112542.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine rich domain-containing protein"
                     /protein_id="HFG9696599.1"
                     /translation="MQTEWNFGYNGSPQSVILKPGKYKFECWGSSGGINNSSWHTDAK
                     GGYSKGEITLKKQTTLYVYVGESGFASSSTSNNTKSGFNGGGKGYLNQQVMGTYYSMY
                     GGGATDIRLVGGAWD"
BASE COUNT        26234 a         6666 c        12039 g        19613 t
ORIGIN      
        1 aaaaaagtaa aattttttca ataaattttt tatttaaagg aaatttattt tttataaaga
       61 aatttcatgt tgtagtatat tttttgctta taaattttgg tactggatat aatattaaac
      121 tgttaatgat ataataaatt taatctataa agtaaataaa attttgtaat aaatagttaa
      181 agctatttta taaggagata tatgatggaa gtatatgctt tggttgggtc aagtggcaca
      241 gggaagagct ttaaggcttt agagttcgca tatgaaaatg atatagaata tataattgat
      301 gatgggattt taatatacaa aaacaaggtt ttagctggga tatcggcaaa acaagcaaat
      361 actactatag aagcagttaa aagggctatt ttttataatc tggagcatag acaagaagtt
      421 agagaagcaa ttaaaaaaga aaatataaga aaaattctta ttattgggac atcaaaaaaa
      481 atggttaatc aaattgtaga gagattgtca attggaaggg tttgcaagtt tataaatata
      541 caagatataa gtactaaata tgaaatagaa atagcaaaac aagctagaaa agaaggaaat
      601 catgtaattc ctgttccagc agttgagata aaaagtatgg caagtggtct tagtataaat
      661 tctttgaaga gactttttag aaaaggaagt aataggaata tggtagtttt agaaaaaaca
      721 attataagac caacttttag ttatatagga aagttttata ttagtgctga tgtaattaaa
      781 cagattattg aatatgaagt atacaacttt ggaagcattg atagaataaa taaaatcaat
      841 atagagaatt gcaataattt tatgaatatt tttgtaagta taaatatcaa tgatttagaa
      901 actataaaaa aaattgaaga catacaacag acaataaaaa agtctattga gaaaatgact
      961 ttagttaatg tacaaaaaat agatattaac attcataaaa ttaaaaaaat aaacttcctc
     1021 caatgttaaa aaataaactg agaaaatgat atactaattt gcaataaagt gtgctataat
     1081 taaactgtaa atttaggaaa tggttttttc taaatggagt atacataatt ataacgtatt
     1141 tataaggggg ctttcaaatg tcaggaaaag atgtaaatgt cttcgagatg gcgcaatctc
     1201 aagtaaaaaa tgcatgtgat aaattaggta tggaaccagc agtttatgaa ttattaaaag
     1261 aacctatgag agttatagag gtttcaattc cagtaaaaat ggatgatggt tctataaaaa
     1321 cttttaaagg atttagatca caacataatg atgcagtagg gccaacaaaa ggtggaataa
     1381 gattccatca aaatgtttca agagacgaag taaaagcttt atctatatgg atgactttca
     1441 agtgttctgt aacaggtata ccatatggtg gaggtaaagg tggaataata gtagatccat
     1501 caactttatc tcaaggtgaa ttagaaagat taagtagagg atacatagat ggaatatata
     1561 aattaatagg tgagaaagtt gacgttcctg caccagatgt aaatactaat ggtcaaataa
     1621 tgtcttggat ggttgatgag tacaataaat taactggaca aagttctata ggtgttataa
     1681 ctggtaagcc agttgaattt ggtggttctt taggaagaac agctgctact ggatttggtg
     1741 ttgctgttac tgcaagagaa gctgctgcta aattaggaat agatatgaaa aaagctaaaa
     1801 tagctgttca aggtatagga aacgttggtt cttatacagt tcttaactgt gaaaaacttg
     1861 gtggtactgt tgtagctatg gctgaatggt gtaaatcaga aggttcttat gctatataca
     1921 atgaaaatgg tttagatggt caagctatgt tagattatat gaaagaacat ggtaacttat
     1981 taaacttccc aggagctaag agaatatctt tagaagagtt ctgggcttca gatgttgata
     2041 tagtaatacc agctgcatta gaaaactcta taactaaaga agttgctgaa tctataaaag
     2101 ctaaattagt ttgtgaggct gctaatggac caactactcc agaggctgat gaagtatttg
     2161 ctgaaagagg aatagttctt actccagata tattaactaa tgctggtgga gttacagttt
     2221 cttacttcga gtgggtacaa aacttatatg gatactactg gtcagaagaa gaagtagagc
     2281 aaaaagaaga aatagctatg gttaaagcat ttgaatctat ttggaaaatc aaagaagagt
     2341 acaatgttac aatgagagaa gctgcttaca tgcattcaat taagaaagtt gctgaagcta
     2401 tgaaattaag aggatggtac taagatttac tcttaataaa taataggata taattattta
     2461 agatataaag gggctgtaca tagtacagcc cttaaattat gtggcttaca atgaagtaag
     2521 ctatttttgt tttaacttat aaaaaacttg ataaattatg taatttagaa tgtatttttt
     2581 accaccacat gattacaaat tagaagagtt agattagatt tttagacatg aacttatgca
     2641 ttttaaaagc aaagacctta atttaaagta tctagtatta tttttaaaaa tagtatattg
     2701 gtttaatcca tttatatata taatggaaaa atatatggat ttggattgtg aactttattg
     2761 tgatgagaga gttttaaaaa attgtactgt acaacaaaag caagaatatg ctctaactat
     2821 tgtaaattca atgaaaagaa gtacaaattt ttcaaataaa tttgtagctg gattaaataa
     2881 acaatctgat attagaaaaa gagtaataaa catgttcagt gaaaaacata aaaatggtat
     2941 cttaagggct ttgattataa gcttgttttc ttctattaca ttttttaaat tcgattcaac
     3001 tagtattatt gaagagaatg atttcttaga gaggtcaaga tatacgtttg aaggaaggca
     3061 agaagacatg tttgtaacaa tagattttat atatgcagat gtacctataa aacttagaaa
     3121 agagcatgaa gaaaactgta gagtcaatgg aatagtacca aaagattcag attcaataga
     3181 aattattcct agattttata aagattgtat ggatttaaaa aaataagtta gacttaatat
     3241 tgatgttgat attatgaatt ttttatattt aagcaattga aaattttatt atagattcaa
     3301 ttttatatgt gtttaagtat gaaatttata gatagttgaa ataattaaat atgattgatg
     3361 cataggaatc attactaagc tataattaat tataagggag tttaaataaa ttatgagtta
     3421 cacaattata aaatgataaa aaatagttat ctgttacaaa aaatgtatct ttttaattaa
     3481 taaagataat atgaaaactt aaaaggcaaa taaacttaaa cataaaatac tcttaaataa
     3541 gataggagaa aaatgtatgt ctaactttat tctaaatggg atttttagaa cagttatagt
     3601 aagtagtcta agcattctta tgatattgat tttcaagaaa aatgtattta aaagatttag
     3661 caaaaaattt aattattata tatggatgat agttgttatt aaattatttt taccatttac
     3721 atattatact tttacaataa atatcttgag aagtaaaaaa cacattaata ttaataacat
     3781 aaatttagag ggatttaata atgtttcaac tataagtaat aatattatat tgtacacttg
     3841 gattataact gtagtagttt atttaattta cactatattt aaatatataa aacttaaaaa
     3901 tttaataaat gacttatctt atgatgttga tgatggagag attgtaaatc tttataaaaa
     3961 tatattagaa gaatttaata taacaaaaga tataaaactc aaatactctt atgaagttga
     4021 aacaccagca ttttttaatt catgtgtgct tttgccacca catgagtata aattgaaaga
     4081 gttagactgg atttttagac atgagcttat gcattttaag agtagggacc tttatttaaa
     4141 atatgtaatc ctgtttttaa aaacagtata ttggtttaat ccatttatat atataatgga
     4201 taaacatata gatttagatt gtgaacttta ttgtgatgaa agagttttaa aaaatcgaaa
     4261 ttcagaggaa aaaaaggatt atgctttaac aattctaaat gcaatgagaa aaggttcaaa
     4321 tacttcaaat aaatttatag ctggactcca taagcaatct gatattaaaa agagagttat
     4381 gaatatgttt aatgaaaagt acaagaatgg tatattaatg gcattaactt tatgtttatt
     4441 atcttctatt acttttttga aggttaattc aacgagtatt gttaatctta atatattgcc
     4501 aaaaggaatg gaagaaaaag atgttactaa tagtgcaatt gttacaatga tagaatttac
     4561 atatgcagaa gctcctaaaa gtatgagaga agaacataaa ataaattgtg aattcttagg
     4621 tttaatacct aaagactctg ataaaatagg tgttggtata gaatattatg acagtctatt
     4681 gaatgattaa ataaatatta ttttaacaga tattaattat aaagttttga atagtaattt
     4741 gttgagaaat aaatatatcc ttataaaaat agatacttat ataccaagaa taaaaaatag
     4801 tcaagatagt acacaaggat atacttataa agaactcaaa taagtgaaat aaattattaa
     4861 ttataaggtt tataatttta aaaaattaga taaattcagg tgtaaaatac tataaaacac
     4921 aattcggaaa agtgtatgtt gaacttcatt taaaatggaa tttcaaagtt gctatagtaa
     4981 gtagtttaag cattcttctt atattaatct ttgagaataa tgtatttaaa aaagttagta
     5041 aaaaatttaa ctattgtata ttaatgatag ttgctattga tatattatct aaaaaaatta
     5101 agtatgaaaa gattactgct aggacaatct tttcatactt aatttttaat atttatatta
     5161 tccaaaattt tcatcttttt aacttagaat ttgagaatca ctattaggaa ataggctttg
     5221 atttatgtag ggttaaaaat ttcacagaat atctaacttt atactaaatc catcaaaaaa
     5281 tatacgccat ataaaagcgc ataaaaaaac acataaaaca atatttatgc gcactttaac
     5341 ctcgaatggt acaaaattct ttacttttac agacccatat tatataatta agtaaataat
     5401 gtatatttag gtgacatatt ggataagcta atttatttat tttattaata taatgatact
     5461 ataaaagtta tataaagtgg tttacaaaaa agttacagat agagctttta ttaatgtatt
     5521 gtgtattagt attttatcct taggtacact tcacctacaa aatagaatca taagataatt
     5581 atgggaaaat tttaggaggt ttatcgtgaa gaaaaagata ttaataccag tatttgcatc
     5641 agttatggca ttatcagtaa gttcaattgt aaatgcagat gaagtaaatg attcatctca
     5701 aaataaggat gataaaacaa atactgaatt aaatttaggt gaatataaag aagtaaaata
     5761 taaagttgca aaaataaaag atggagtagc tataaagata agagaagaag gtcaagttca
     5821 aaacatagct tattctggag atgaatttac ggttttagga actcaaggag aatgggttaa
     5881 ggttaaagtt gaagatggcg aaggttggtt agctactaga tatgtagata tatctgaagg
     5941 tgtaggatat actaacgctg ataaagtaaa cttaagaaaa gataagagtg aaagttcaga
     6001 agtaattgaa gagctggaaa aaggaagttc tttattggtt ttggaagata atggagattg
     6061 gttaaaagtt aaagatgggg aaacagaagg atatgtaaaa tcatcttata tatctgataa
     6121 agctcctgta atagaagagc cacaagtaaa cccaagtatt gaccaaaatg tagattctac
     6181 aaataataat caacaaaaca atgcaaatac taatcaacaa aataataatt caaatgtgcc
     6241 aacagctaac tctaatgcag ttcaagctgt acttaacttg gcatattcta agcaaggttg
     6301 tccatatgtt tggggagcag aaggaccaaa cacttttgac tgttctggat ttacacaata
     6361 tgtgtataga aatgcagtag gaaagaatat accaagaaca tctaaagcac aatctaaata
     6421 tggacaaact gtaagtaaag caaatttaca accaggagac ttagtattct tcacaactaa
     6481 tggttctggt tctgttagtc atgttggaat atatgtaggt gggggtaata tgatacattc
     6541 accatcaaca ggaaaaacag ttagtgtaac tagtataaat tcatcatact atacagcaag
     6601 atttgttaca gcaaaaagaa tattataatc ggtttgtaat atgacaaatt gataaataca
     6661 taaatatata taaacgctct atattatatt taatttaatc atggaaacaa aaaatgatta
     6721 tattttaaat gtactataga gcgtttttgt atcactttaa atctaatcaa gattcaagtt
     6781 aatatgactg ttaaatagga gccttttcat atgatgatta tttgcgcaat cccttgacag
     6841 gatagggcaa aggtggtaag ctactaacag tacaaaaata cttttaattt tagttcagag
     6901 aggctaaaaa aggaggacga aagatgttaa aatcaagaaa tttaatccag ccagaagact
     6961 tttcaataga agaaatagat gaaatattag aattagctca aaaaataatt gacaatccgt
     7021 caaaatattc tcgtatatgt gaaggaaaac tattagctac attattttat gaaccatcaa
     7081 caagaacaag attaagcttt gaatctgcta tgaacagatt aggaggacgt gtagtaggct
     7141 tttcagagcc aaattcatcc tctgcatcaa aaggtgaaac tctaggagat acaatgagga
     7201 tagtatctgg ttatgttgat ataatagcta tgagacatcc tcaatcaggt gcagcttcag
     7261 aagcagctag atatacggaa gtgccattta taaatgcagg agacggcaaa aaccagcatc
     7321 caactcaaac acttacagac ttacttacta taaaatcatt aaaaggaact ttagaaagcc
     7381 atacaatagg attatgtggt gatttaaaat atggaagaac tgtgcattct ttggttaagg
     7441 ctatggcaag atataaaaat acaaagtttg tatttatagc gcctgaagag ttaaaaatgc
     7501 cagattatat aaaagaagct ataaagggac atgcatatta tgaaactaat aatttggatg
     7561 atgttatagg aagcttggat gttttatata tgactagagt tcaacaagaa agatttgaag
     7621 ataaatcaga gtatgaaaga cttaaaaact attatatttt aaataaagct aaattagaaa
     7681 aggcatctaa agatatgtta gtaatgcatc cattaccaag agtaaatgaa atagacatag
     7741 atgtagatag tgatgataga gctgtatatt ttaaacaagc taaatatgga atgtatgtta
     7801 gaatggcttt aataataaaa cttttaggta taaatgaaga ctaatagtta tcatataata
     7861 gtaaaacaaa ggagattttg ggatgtataa aattctggaa aatatatata taggcgaaga
     7921 tatgtataga atgaaagtaa aaggtaattt tgaaggtaaa atgggacaat tctatatgtt
     7981 aagagcatgg gatacttatc cagtactttc aagacctata agtatacatg atatagatga
     8041 agaagggata acttttcttt ataaagtagt aggagaagga actcaaattt tgagtaacct
     8101 aaaggtaaat gataatataa aattagaagg cccttatggt aatggatatg ctaaggttga
     8161 tggaaaggta gctctagtag gaggaggaat cggtgtagct ccactatatt tggttgctaa
     8221 aaatataaaa aattgtgatg catatcttgg gtttagagaa gatgttatat tagaagatga
     8281 atataaacaa gtatgtaata aagtctatac aacagtagga aatacttttg taacagatat
     8341 aattgatgtt gagaaatatg attatatatt aacatgtggt ccaactccaa tgatggaaaa
     8401 attagttaag atggtagaag gtactaaaac gagaattatg gtatctcttg aaaaccatat
     8461 ggcttgtgga gtaggtgcct gtttagtatg tacgtgtaaa actaatggag gaaataaaaa
     8521 gacttgtaaa gatggtccag tgttctgggg agaggacgtg atttttaatg ggtaatttaa
     8581 gtgtgaaatt tggaagtgta gaatttaaaa atccagtaat aatggcgtct ggaacttttg
     8641 gatttggaaa agaatataat gagatttatg atatacaaaa acttggtggt ataagtagca
     8701 agggtcttac tttaaataaa aaacctggta acaatggtat gagagttcat gagacatcat
     8761 ccggtatgat gaatagtgtt gggcttgaaa accctggagt tcaaggattt atagactatg
     8821 aattaccttt ttttagtaaa ctagacttag tcagaatagc taatgttgga ggtgggacat
     8881 tagaagacta cttattaggg gttcaaatgt taaatgacaa gcctatagac attattgaat
     8941 taaatatatc ttgcccaaat gtcaaagctg gtggaatggc ttttggtata aaaaatgaag
     9001 tggcaagaga agttgttcgt gaggtaagaa acataacgaa actgccttta gtaataaaat
     9061 tatcacccaa tgcagaagat attgtaggaa tggcaaaagt ttgtgaagaa gaaggtgctg
     9121 atggagtttc attagttaat acttttaaag caatggcaat tgatataaaa aatagaagac
     9181 cagtatttga aaatgtatat gctgggttat ctggaccagc tataaaacct atagctttga
     9241 gaatggtaca tgaagtgtgt aaaaatgtaa atatacctgt aatgggaatg ggcggaataa
     9301 ctaaagccac agatgctata gagtttataa tggcaggagc tacttgtatc caagttggaa
     9361 ctgcaaattt tatgaatcct agaataggta ttgaaataat agatggaatt aatgaattta
     9421 tggatagaga aggaataaaa agtttagacg aaataagagg aattatataa ggtagaataa
     9481 atagtatttt aaagataaaa aatatagatt aaataaacaa taattttata acattaacat
     9541 ggaggaaaaa taatatgagt aaagtagatg tagtggatat attaaagaaa agtgatgcat
     9601 tgttggaggg acatttttta ttatcttcag gaaaacacag taatagatac gtacaatgtg
     9661 caaaagtatt aagatttcca gaatatgctg ctgaggtatt aagtacagtt gttgaacaaa
     9721 taaaagactt agatatagac ttagtagtag gaccagctat gggtggagta atagtttctt
     9781 atgagttagg aagacaatta ggaaaagaag ctgtatttac tgagagaaaa gacaatacaa
     9841 tggagttaag aagaggattt gaagttaaaa aaggagcaaa gataataatt gctgaagacg
     9901 ttgtaactac tggtaaatca actatggaga caaaaagagt attagaagcc ttaggtggag
     9961 aagttgtagg tgttgcatgt atagcagata gaactaatca tgatataggt atgcctatat
    10021 atagtgctat aaaacttgat attcaagttt atgaatctga tgagtgtcct ttatgtaagg
    10081 aaggaaaatt accagttgtt aagcctggaa gtagagagtt caaggaatta gggatgtaat
    10141 aaaaacttaa ttatttatag tgttacttaa aaaatgtaaa ttttttagag taaaaatttg
    10201 taatataaca tataacttaa aaataaaaag cagttagcct tataaatgaa ggttagctgt
    10261 ttttttgtta aaaatatatt tacaaaataa gagatagtag cagtacaata taagtataag
    10321 gtaaaagtat tatatattag ggaggggtaa gtatgaaaaa tcaattaaat gaaaatcata
    10381 aaaaggttgt attttttgga gtaggtgctg taggagctac ttttgcagaa caatttttta
    10441 actctaaata tgattttaaa attctttgtg ataatgaaag aaagaaaaga tatttagaag
    10501 aaggatttat aataaatgga aaaaggtatg attttgatta tgtaactaaa gatgagtata
    10561 aacaagaggc tgattttata attataggtc taaaatataa taatttaaaa gaaaatataa
    10621 aagaattaga tggattagtt ggaaaaaata cagttataat gtctctgcta aatggagttg
    10681 atagcgaaga gataatagga gaaagatttg gaattgaaaa aatggtatat tcatatgtta
    10741 ccaatataga tgcaaagaaa atcaataata atattataca cactactaat gggataattg
    10801 tatttggtaa caaagataat agtgaagata gaaaaactaa tataataacc gaagtctttg
    10861 atgatgtaaa tatagaatat actttatcaa aagatattca acgagatatg tggtggaagt
    10921 acatggttaa tattggtgta aatcaaactt cagctatact tggtgcacct tatggagttt
    10981 ttcagagttc tgagcattta agagaattag caaaatctgc aatgagggaa gttgttgcta
    11041 tagcacaagc aaaagacata tctcttacag aagatgatgt ggaacattca ttacatagaa
    11101 tactagaaca ttcaaaagaa ggaagaacat caatgcttca agatgtggaa gctcatagac
    11161 ttacagaagt agatatgttt tctaagaata tctgcaaact tggaaaaaaa tataacatac
    11221 ctactcctat aaatcagact ttcttttata tgataaaagt aattgaaagt agattttaaa
    11281 gggtctttgt aagaaatatt gataattatt gattttaaat tttattaatg ttatatacta
    11341 tttaagttac taaatatttt taactcttca atgaaaatag ttgctgcttt tgataaagtt
    11401 atatcttttg gaaatatata tgagaaatgt ctgttgtagc tgcttccaag ctctatgaca
    11461 gacagctcat tgtttagaac aggtaagctt gtcactagat tagagactat tgtaattcct
    11521 aaattatttc taacagattc tttgacagca taattacttc caaaaaccat catacttttt
    11581 ggaataattt ctttaacact taaaaacata tctaaataat ctctggttcc agaaccatcc
    11641 tccctgacta tccatttttg gttttgaagt ttatcaaaac taaaatcttt taataaatga
    11701 ctcttgtatg gaagtgctaa aaccatctta tcttcaaaaa aatattcttg aataaatgaa
    11761 ggggaagagc aagtgccttc aataagacca atgtctaaaa tataatcctt aacatgagaa
    11821 gatacgattg atgtattttt tataaaaact tctacatcta tgtcaggata ctttttagaa
    11881 aataatgcta gaaaatttgg taaaatatac tctccaatag ttaaacttgc accaatcttt
    11941 aagtgaccag ttatagcatc tgaaacttgg cttacatcat gataagtaat atttaaaaga
    12001 tttaatattt ctttagctct tttgtacaag atttgtccac tttctgttat aaaaatggtt
    12061 ttttgtttaa tagacctgtt tataagcaca actttaaaat aattttctag attttttatg
    12121 tgtttactta cacttggttg tgatagattt aaatattccc cagctttagt aaagtttttg
    12181 tattcaacaa cagctacaaa tgtttttaat tcttcaaaca attttttgtc tcctttacct
    12241 aatgaaattt tacatttttt atatactttc tacagataat tatactatat ataataacca
    12301 ttaaaaacat taatcattac gatattatat atttatttta cttatggtta ttacaattat
    12361 atactattgc tatgaagaaa actatattaa ttataaggta ggtatattat gttaaagaaa
    12421 aaaagcagtt tgacattaaa aactataagg gaaatattac caggactgtt tgtatcagta
    12481 ttagtaggtt atattagtat atttatttct attttaattc ctaaggtagg ggcagcatca
    12541 atttctatat ttttaggtat gtttgtagga aacctatttt taaatcaaaa ggtatttcaa
    12601 aaaggttata aattttcaga gacagatttg ttatcatatt caatagtact attaggagca
    12661 acactcagtg tatctacctt aatagactta aaagtttcag gaattttatt tataatattg
    12721 caaatgacaa taacaataat agctgcactt tatataggta aaaaactagg atttgaagaa
    12781 aactttagat ttctaatggc aagtggaaat gcagtatgtg gttcttctgc aataggagca
    12841 acagttccag tggttaatgc gacagataaa gaaaagggaa ttgcagtaac tattgtaaat
    12901 gttactggta tatttcttat gtttttactt ccaataatat ctcaattttt atatagccat
    12961 gaacttgtaa aaacttcagc aatgataggt ggaactttgc aatcaattgg tcaggttgta
    13021 gcaagtggag caattgttgg agaaaatgta aaagatttgg ctactatttt taagatagta
    13081 agagtaatat ttctagttgt tgttgtatta gtatttggac atatgaaaaa tcaatctaat
    13141 agggaaattc ttgaagaaga aaaggatgag ataaaaaaga aaaaagtgac tataccatgg
    13201 tatgtaattg gattctttat aacttgtgca cttttttcaa tgaacattat accaaaagaa
    13261 gtatctgtgt tgtgcaaaga aataagtaac aaactagaaa taatagcttt agcagcaatt
    13321 ggattaaagg ttaatgtaaa agatttagtg aaacaaggga aagaagtttc tttatatggt
    13381 ttatttgtag gtatagtaca agttgtatca gctgtagttt taataaaaat atttatatag
    13441 cataaaaata gtatttgtaa tattaatttg attaactaaa ataatatgat actaataatt
    13501 tataatataa ataaaaaatg aatttcgata agtttaagtg ggtataaact tatagaaatt
    13561 cattttttat ttaaggtaaa aatttaaagt aaaatattat tttacataat aataacctta
    13621 taaattttga aattacttat ctttgtgtta aaataagtaa aatgcacata ttagagctaa
    13681 gtttttaagt aaataaacaa aatgaaaata taaatattaa ggagatttgg tatatgaatg
    13741 tttatgaaaa aggtaatgga gttatactag aaggagtaac agattttgac ccagtacata
    13801 tatttgagtg tggtcaatgt tttagatggc acaaacaaga agatggctca tacactggag
    13861 ttgcaaaggg aagaatatta aatgtcaaaa aagagaatga taaaatatat ttaaataata
    13921 ctaatttaaa ggagtttaac agcatttggt ataattactt tgatttagga actgattata
    13981 cagaaataaa gaataagcta aaaaatatgg atgaatattt aaataaggct actgaatttg
    14041 gatggggaat aagaatatta agacaagatg gatgggaaat gcttatatca tttataattt
    14101 cctctaataa taggattcct atgatacaaa gagcgataga aaatttatca agaaagtttg
    14161 gtaagtatat aggtgaatat gaaggtaatg aatactatgc attcccaaca ccagaagaac
    14221 taaataaggc ctcacaagag gaaataagag catgtcaaac aggttttaga gataagtaca
    14281 taaaaagtac tacacaggca gttatagaga ataatgatga ggtatctgaa tatacaaatt
    14341 taagtacaga ggattgtaga aaagagcttt taaaatttaa tggagtagga ccaaaagtat
    14401 gtgattgtat tgcattattt ggtatgcaaa aatatgattc ttttccagtt gatgtttggg
    14461 ttaagagagt tatgcaagaa ttttatatag atgaagacat gagtttacct aaaatgagaa
    14521 cttatggaat cgataaattt aaagaaatgt ctggatttgc tcaacagtac ttattttact
    14581 atgcaagaga actcggtata ggaaaataaa ttaaggggga gaaattatgg gagtaatagg
    14641 aacaatattt ctgttctatt taattatatc atatctagct ggagccataa tttctgtgat
    14701 tatattgctt gaaaatagag accctgcaaa aacaatgtct tggctattga tgtttattat
    14761 atttccaggt gtaggtttaa tgatatatgc tatttcaggt agaaatatta gaaaaagaaa
    14821 attatttaag actcaaaaac tagctaataa tataaaagaa aagaaactat ttgatacatt
    14881 agaaaagata acagaaatag ttgaattaga aaaagaatct ataaaacaaa ataagctttt
    14941 aagagatgaa gaggatggta gttatagaaa aagggtaata aatatgttgt taaagactgg
    15001 tatgtttccc tttactaaaa ataataaagt ggatgtattt gtagatggaa atgaaaagtt
    15061 taaaagactt atagaagata taagagaagc taaagaccat attcatttag agtactttat
    15121 catcaaagat agtgaaatag gtagggtgtt aaaagaagaa cttataaaaa aggctaaaga
    15181 aggcattaag ataagaattt tatatgatga tgtaggatgc tggagatttt ggtttaatag
    15241 aaaatttttt cgagaaatga gggaagtagg tatagaaatt gcagcatttt tacctacaaa
    15301 atttcctata ataggaggga aattaaacta tagaaatcac agaaaaattg ttgttattga
    15361 tggaataatt ggatatacag gtggaataaa tataggagat gaatatttag gcaaaaatga
    15421 taagtttgga tattggagag atactcatat tagaattaag ggtatttctg tatacatgct
    15481 tcaaatgaca tttctgattg attggtatta tacgacaaaa gaagtattag tgactaaaaa
    15541 ttatttccca agtgtaggga atgttggtga aagtatgata caagttgttg cgagtggtcc
    15601 agacagtgac tgggaagata ttcattatgc ttatttttct gcaatatgtc aggctagaaa
    15661 aaatgtttat atagaaactc catattttat tccagatgaa agtctactaa aagctataaa
    15721 gagtgctgct cttagtggag ttgatgtgag aataatattt cctaaaattg cagaccacaa
    15781 gatagtaaat atagcatctt attcatattt tgaagaaata ttaagagcag gtggtaaagt
    15841 ttatttatat aataaaggat ttatacattc taaagtcgta ataatagatg ataaaattgc
    15901 ttctgcaggt acagctaata tggatttaag aagttttatg cttaactttg aggtaaatgc
    15961 atttatctat gatgaagaag ttattagggt aatgacagat gatttctttg aggatttaag
    16021 tcactgtgaa gaacttaatt tggaggtatt taagaataga aatatcatac aaaaaatcaa
    16081 agaatctgta gcaagattat tttcaccaat attataaaaa attattaaaa aaggtattga
    16141 aaattatgtg tgattggtat attataataa ttgttagcac tctattagat agagtgataa
    16201 taaataaaaa gtatatatat aaatctacat atataagtag tattaattta aaaataacta
    16261 aaaacatagg cgaactagtc tatacttaat attttaggag gcgtgaataa tgaaaataag
    16321 accattagct gacagagtag taattaaaaa agtagaagca gaagaaaaaa ctgcaagtgg
    16381 aatagtttta ccaggagcag ctaaagagca acctcaaata gctgaagttg tagaagttgg
    16441 accaggtgga atagttgaag ggaaagaaat aaaaatggaa ttgacagtag gagataaggt
    16501 tatattccaa aaatattctg gaacagaagt taagatagaa ggacaagaat acacaatact
    16561 aagacagagt gatgtattag ctgttattga ataaatatag aataaattta ttaggagggg
    16621 tttaaaatgg ctaaagaaat taaattttca gaggaaacaa gaagagcttt agaagctggt
    16681 gtaaataaat tagcagatac agtaaaagta acattaggac ctaaaggaag aaatgttata
    16741 ttagataaaa aatttggttc tccacttata actaatgatg gagtaactat agcaaaagag
    16801 atagaactag aagatagatt tgaaaatatg ggtgctcaat tagttaaaga agtagcaact
    16861 aaaactaatg atgtagctgg agatggtact acaactgcta cagttttagc acaagctata
    16921 ataagagaag gtttaaagaa tgtaacagca ggggctaacc caatactttt aagaaaagga
    16981 atacaaaaag cagtaacagt agcagtagaa gaattaaaaa atcaatcaag aatagtagaa
    17041 acacaagagg ctatatctca agttgcttct atatctgctg gtgatgaaga agttggaaaa
    17101 ttaatagcag aagctatgga aatagtaggt aaagatggag ttataactgt tgaagagtct
    17161 caaactatga atactgaatt agatgctgtt gaaggtatgc agtttgatag aggatttgtt
    17221 tctgcatata tggttacaga tgtagataaa atggaagcag ttttaaacga cccatatata
    17281 ttaattactg ataaaaaaat atctaacata caagaattat taccagttct tgaacaaata
    17341 gttcaacaag gtaaaaagtt attgataata gctgaagatg tagaaggtga agcattatct
    17401 acattagtag taaataaatt aagaggaaca tttgatgtag tagcagttaa agctccaggc
    17461 tttggagata gaagaaaaga aatgcttcaa gatatagcaa tacttacagg tgctcaagta
    17521 atatcagaag aattaggtta tgatttaaaa gaagctgatt tatctatgct aggtagagct
    17581 tcatctgtta aggtaactaa agaaagtact acaatagtag atggttctgg agataaaaaa
    17641 gctatagaag atagagtaac tcaaattaaa catcaagtag agcaaactac ttcagatttt
    17701 gatagagaga aattaatgga aagattagct aaacttgctg gaggagtagc tgttgtaaaa
    17761 gttggagctg ctacagaagt agagttaaaa gaaagaaagt taagaataga agatgctctt
    17821 aatgcaacta gagcagctgt agaagaagga atagtagctg gtggaggaac tgcttttgtt
    17881 agtgttatac cagcaatagg aacactaatt gagagtttag aaggagaagt taaactaggt
    17941 gctcaaatag ttaaaaaagc gttagaagag ccattaagac aaatagctat aaatgctggt
    18001 cttgaaggtg ctgtaattgt gcaaaatgtt gttaattctg aagcagaaac tggatttgac
    18061 gcattgaatg aaaaatatgt aaatatgata gaagctggta tagttgaccc aactaaagtt
    18121 agtagaagtg ctttacaaaa tgctgcatca atagcaagta ctttcttaac tactgaatct
    18181 gctgttgctg accttcctga aaaagaagat gcaggaatgc caggaatggg tggcggaatg
    18241 cctggtatga tgtaatttaa aaaatttaaa atataaattt taatataaag aactatttcg
    18301 acttagattt taaactctaa gttgaaatag ttcttttgta tatatctaat ttttgtatat
    18361 ctataaattc aatacacata tttagataat cagtatctag tttgtaataa tattttagag
    18421 tagtattgtt attttttagg ttatgatttt agatatatat taattaaggt ataattgttg
    18481 atagagaata aatcaaattt aaaaggatgc gataatatgg acttaagaaa attgcttgaa
    18541 gaagttaaaa atgaaaatat tgatatagat tttgcgttag aaaagttaaa agatttacct
    18601 tatgaagacc ttggatatgc aaatatagac catcatagag aattaagaaa tgggtatccg
    18661 gaagttattt attgtgaagg taagagtgat gagcatattt tagggattat tgataaaatg
    18721 aatcaaaaaa gttctaacat attggggaca aggtgcagaa aagaaacttt tctgaaaatt
    18781 aaagaaatct ataatcatgc tgagtacgaa gaggcgtcta aaattcttaa gattcaaaat
    18841 catgatatag agaatatagg aaaaggtaaa attgtgattg ctacaggggg aacttctgat
    18901 ataccagtag cagacgaagc ttatcataca gctaagtttt taggtaatga tgttgataga
    18961 atatatgatg ttggagtggc aggtatacat aggcttttaa ataaaagaca taaaatagat
    19021 agtgctagag taatagtagc cgttgcaggt atggaaggtg ctcttgcaag tgtaattggt
    19081 ggactggttg atgttccagt aatagctgtt ccaacttctg ttggatatgg agcaaatttt
    19141 ggaggattag cagcattgct agctatgtta aatagctgtg catctggaat atctgttgta
    19201 aatattgata atggatttgg agcaggatat ttagcatcaa tgataaataa actgtaaata
    19261 cattgatata aattaaacaa aactatataa taaaatttaa tttctattat atttttacta
    19321 ttaaaattga ggagacatat atgagtgaaa aaatacttta ttttgatata ataagcggta
    19381 tatcagggga tatgaccctt gcaagtttat taaatttagg tgtgcctaag gaaatttttt
    19441 tggaggaaat tcataaacta agaatgagcg atgaatttaa tataaacatc agctcgaaaa
    19501 ctgaaaatgg aatagtaggt acaaaagtag aagtaattac aaaagaaaaa catacacata
    19561 gaaatttagt ggatatattt gaggttatag ataaaagcac tctaaacgaa aatgtaaaat
    19621 ctaaagcaaa aaaaatattt atggtaattg gagaagcaga agcaaaagtt catggaacta
    19681 caatagacaa gatacatttt catgaggtag gggctataga ttcaattgta gatatagtag
    19741 gagcttctat attagttgac ttactttgtg tagataaagt ttgtgctagt acagtgtctg
    19801 ttggttcagg atttgtaaaa tgtgaacatg gaattatacc tatacctgca cctgcaacta
    19861 tagaaatttt aaaaggtgtg ccaattaaat taaataatgt aaatggagaa tgtacaactc
    19921 caacaggagc tgcaatcata aaagttttgt gtgatgagtt tgtagatgag cttgaatttt
    19981 ctccaaagca aattggatat ggtataggtc ataagaagtt tgaagtacca aatatactca
    20041 gaactgtatt aggtgaaaaa aaaaagaaga attaatttat gaaattagtg caaacattga
    20101 tgatatgtct tcagaaatct attcttattt gtatgaaaaa atattagatg agaaagcatt
    20161 ggatatttat acagagagca tttatatgaa gaagaataga ccagcaacaa aagtatcaat
    20221 tttatgtagt gaatcagatt tagaaaaatt tattaaaata ttacttttag aaactagtac
    20281 ttttggagtg agatataatg catataatag agaaattcta gagagaaaat ttgtaaaatt
    20341 agatacaaaa tatggagtgg ttacagtaaa actagggtat tataaaggaa aactagtcaa
    20401 ggctactcca gaatataatg aatgtaaaac tatagcaaaa aatgaagata ttcctataaa
    20461 aaaagtgttt gctgatataa attttagaat aaaagaagaa tttagtgaaa acttattgac
    20521 ataagtaata aattttgata aattaatatt cagccttatt aaataaaagt aaacagaaaa
    20581 aaatatataa aatataaact cactcgtata tgctcagaaa tatggtctga gagtctctac
    20641 caagataccg taaatatctt gactatgagt gaaattatta taccaaaaga cctagttaag
    20701 taaatgtgta ggctgagtta aactccctat gtgttggcta taagataaag gtattttgga
    20761 agcctgtata gtaatttcac ttttgctaga aattatggaa gttactatac aggttttttg
    20821 tgtaaaaaga tttaatataa tttagactgt attgtgttaa aataaatata taaaaactat
    20881 attatacaag gagagatgtg aatttatgaa acatgaatta gtacttgtaa tagattttgg
    20941 aggacaatat aatcagttga tagctagaag agttagagaa aacaacgtat attgtgaaat
    21001 acttccatgt actgcaagca tagaaagaat aaaagaaaaa aatcctaaag ggataatatt
    21061 tacaggcggt ccaaatagtg cgtatttaga agattctcca acaatatcaa aagaaatatt
    21121 tgaattagga gtaccaatac ttggaatatg ctatggtatt caaataatgt ctcatgtatt
    21181 gggtggagtt gtaagaaaag gtaataaaca agaaaaagaa tatggaaaaa cagctataac
    21241 ttatggaaaa tcatcattat ttgaaggaat aactacaaat agtgtatgga tgagtcatac
    21301 agatttaata gaaaaagttc cagaaggatt tactatagtt gcaaatacta atgattgtcc
    21361 agtagcagct atggaaaatg tagaacgaaa cctatatgga gttcaattcc atccagaggt
    21421 ggaacactgt ttggaagggg ataagatact tacaaacttc ttatataata tttgtaaagt
    21481 aaaaggtgac tggactacag attcattcat agaagataaa ataaaagaat taaaagaaaa
    21541 aataggcgat aaaaaagctt tatgtgcttt aagtggagga gttgattctt ctgttgctgc
    21601 agttcttatt cataaagcaa ttggggacaa cttaacttgt atatttgttg accatggttt
    21661 acttagaaaa aatgaaggaa atgatgtaga aagaatattt agagagaaat ttgatataaa
    21721 tttaataaga gttaatgcag aagatagatt cttatctaaa ttaaaaggag tttctgaacc
    21781 agaagctaag agaaaaataa taggtgaaga atttataaga gtatttgaag aagaatcaaa
    21841 taaattagga aaaatggatt tcttagtaca aggaacaatc tatccagatg ttatagaaag
    21901 tggacatgga aatgctgcta ctataaagtc tcatcataat gttggtggaa tcccagaaga
    21961 tgtagacttc caagaaattg tagaaccatt aagagagtta tttaaggatg aagttagaaa
    22021 aataggatta gagcttggta tagaagaagg attaatattt agacatcctt tcccaggacc
    22081 aggtctagga ataagagtta taggtgatgt aactaaagaa aaatgtgata tattaagaga
    22141 agctgatgct gtttatatgg acgagcttag aaaagcaggt ttatacagag aaatatggca
    22201 agcttttgca acattaccag atgttaagac tgttggagtt atgggtgatg aaagaacata
    22261 tgcttattta gttggtttaa gagcagttac ttcttctgat ggaatgactt ctgactggta
    22321 taagatgcct tatgatgtat tagaaagaat ttctaataga ataataaatg aagttgatgg
    22381 agtaaataga gtagtttatg atataacttc taaacctcct ggaactattg aatgggaata
    22441 gtaaataaaa aagtcgtaag ccttgtattt tcaaggtttg cgacttttaa aaaaatcttt
    22501 gtgatactaa aatgatacta tatatttaaa ttatctagtt tttgggcaac ttcaagttgc
    22561 ttatttgggt ataaatgtga atatgtattc caagttgttt ctactttttc atgccccaat
    22621 ctttctgcta tagttaatat atttacatcc atatttacca ataatgacgc atgagaatgt
    22681 ctcaaatcat gcactctaat tctttttaca ttagataact tacagcatct atctagctct
    22741 ttagaaagat aacttttagc aaatttaaat attctttcat tatcttttaa gtcatatagc
    22801 ttagatagat aatcttttat attattatat aagaaatgtg ggatagggac aacacgttta
    22861 cttttaggag ttttaggaga agaaacaata tcctctccat ttagtcttat gtagcttttt
    22921 tcgacgctta ttttattttc gaaaatatct tttggagtaa gagctaacaa ctcccctagt
    22981 ctaagacctg tccaaaataa aatttcaaat gctagtctag gttctgattt cttttcaaat
    23041 tcaataaatt ttttaaactc ttctaatgtc caaaagttca tttcatctgc gtttttttta
    23101 ccgatagaac ctgccaaatg agcaggatta gaaggtaagt tataatattt aactgcataa
    23161 tttaatacag caacaagctg gttgtttatc gttttaatat atgtttggct ataatcactt
    23221 tttaataatt cgttttgcca tcttcttata tgtgttgcag taatttcatt tatttttaga
    23281 cttttaaaaa aaggtaaaat tctaaagttt attaaatact ttttagtttc taatgtagat
    23341 aattttaatc tagaagacat atcgtgcatg tattcttcta tgagactttc aaaactcata
    23401 tcagtactca ttttagattt attcaaaaat tctctttcaa actctagagc ttctttttta
    23461 gttttaaaac ctctcttaat tttctttttc ctatccccat cgaagtctgt aaaataaaag
    23521 ctagcatacc aactttttct ttgttcgtct ttgtaagcag gcattttaga cacccccaat
    23581 tatgtcattt taatattaca ataattataa catgttagat atgctatcta aataattgtt
    23641 ttattttcct cttcttttta tttcttgaag cttgtaatat ttacacagtt ctaagaagtc
    23701 ttcttctagt gctatagata agtctaatat cgtagatata cctatatctt tgtactcttg
    23761 attttctagt tttgatatat aacttctgtt acgtctcatt ttttctgcta attctagttg
    23821 tgtcattctt ttcttttttc ttaatttttt caacatttat taaaatccac cttttaatta
    23881 tttttatgac atttttataa ttaatagttt gtgtaatttc ttgtaaaaaa tgttcctcat
    23941 tagaacattt tttggtggaa aaatgtgtta aaatgtaagt aagaaaagca ctttcaaagc
    24001 actataaaaa tagtgctgaa atagataaac aaataaaagt aataaggagg aaagatagat
    24061 tctagaggga aatcattatc atttttaaga acgtatgttc ggttggtggg atagaaaaat
    24121 actttacagg ggatggttta tttgaatgag aatgaaaata tgagtttata tgtcagtaag
    24181 ttaaaagaag tattgaaaaa taattcagaa gagtataaaa aaataagagc taaaataaat
    24241 gaaatttata atctaaatga aaagaaagaa taaaagggct ttagctcttt tattctttct
    24301 tagtattaac tgctttataa taagcattat ctatcatttt ttttattgca tttttatcat
    24361 ctgaatctaa agatgctaat ctatttatta gttcgttaac ttcattatct tcttttgagt
    24421 taactttttt taataattca tcatcttgtt gagtgttagg ttgtatttta cctaatttag
    24481 ttaatagctc ctttaaagtt aaatttaatc caaaactcat tttttcaagc atatctaaag
    24541 taggttcaac agctttacca ttccttgggt ctctgttttt ttctatctta tctatatatg
    24601 tatggctcac accacaaaga ttagaaaatt ctctaagaga taagttatgt tcacttctat
    24661 attctttaat aatttctgct aatgtttgca taatttcaca cctcatctaa gtaatagttg
    24721 acttaattat atcagaaaaa tgtaaactat tgttaacaaa aataaaaatt tagtaaaaaa
    24781 taattgacaa gagtaaaaaa aagacgtata ctatgattaa caaaaaggtt ataaataaag
    24841 ttaggaggga ttaatataaa aaataattta caatatatta gaaaagaatc tagaatatca
    24901 caaaaaaaat tcgctgataa gataggtata tcaagaccgt atttatctag aatagaaaac
    24961 ggtaaggtta atccgagttt agaaatagcg cataaaatct cgctcgaaac agggaaaaca
    25021 ataaatgaaa ttttttttga ttttactgta aatcatagta aactataagg ttttaattgt
    25081 accttgaaaa ctaaatataa aatattttaa aggagcaagt atatgaaaaa taaagaaaaa
    25141 gaaataatca ttagaggaat tttaatagga attttttatt ttttaggaat tgtatttagt
    25201 aatacttttt ttaaataata aatagaaggg gtaggtgaaa taccaactcc ccaaatcaaa
    25261 ataacacttt ggaagttaaa tataaaatat tcaaaagagg tgattagatg caaagagagc
    25321 aaacaacgct tcgtatacca gaagacttgc acaaagcgtt gatagattta agcagtgata
    25381 taggaatgcc tattacatct attataataa ttgcatgttg gttgtatata tcaaagataa
    25441 attaaccaat ccgatatgca aaatgaatgc acaacattat ttattagaga attgattgat
    25501 aaattatttt ctttagctgt tttctctagc aactctttta ggacaccagg aatcctaaga
    25561 gtagaacgaa cagtatcatc acttttatac gagattgatt gaagttcatt aacttttgaa
    25621 tttctaataa tatcattaat agcgtataga ataagcgaag atttgagaat gcctgtttga
    25681 taagaaattt tttctaaatt ttcatttaat ggtgtatata ttcttacagt aatagtagtc
    25741 attttgacac ctccctaatg acattataca aaaaatattt aaaaaagtct tgacactaaa
    25801 atagtgtcat aatataatga ttatagacag taaaacagtg tcataaggag ggaggaataa
    25861 gaatggaaaa agtaagaatg acagtaaggc tcgtcccaaa attaaatcaa tatgtacaga
    25921 atatagccaa agaatgtgga aaaagtaaaa attctattat tgtggatgca tgttgggagt
    25981 ttattgagaa aataaaaaaa gaaaataaat tcaatgtaga aagcgaggaa taaatatgaa
    26041 taatctacag atatttgaaa aattggaatt tggacaaata agaatggcag agattgataa
    26101 taagccttac tttgtaggaa aagatgttgc aaagtcatta ggttataaaa atactaatga
    26161 tgcaatttta agacattgca aaggggtagt gaaacacgag gggtttaaaa ttaatggtat
    26221 taagattgct ttgataactg agggtgatgt ttatagatta atagtaggtt caaatctacc
    26281 aaatgcagaa aagtttgaga gttgggtgtt tgatgaagtg cttccaagca taagagaaac
    26341 aggtcaatac caagcacaac agcatgtaat aacagaactt acaggaacta taggagactt
    26401 aaaaggaaca ataaaagaat ataaaaagtt gtgtaagata acatgctcta agaaacaaca
    26461 gtattctaaa tacataaaga atagactgga tatagacaaa gctaataaag aatacaacca
    26521 agtgaaagca aggctattcc taattcttgg agttgagaag tgggaagaca tagacttcga
    26581 tacatctaat aatttaatac aaattataga tgattgtata agagttataa agtcagagag
    26641 accatacaag cagttgagtt attttgaaaa ctaaatacag aatattttga aatatattgt
    26701 tttaattaat tattaactag gaggttaaat acatgaaaaa taatataagc gattcaagag
    26761 taaaatattt ttgcaagtgt ccatactgtg ggtttgataa tgaggtagaa gttaaaaaag
    26821 gattgaagcc taaaatatgt tgcatatgta caaaagaagt tgagtatgaa aaactggagc
    26881 aacaaagtac tccagcaaaa taaaattaat aaatatgaat atttttacaa gaatctaatt
    26941 ctttttctaa cttattaaca gcatggttat attgcagtgc ctgttctgct ataaagttag
    27001 aatttgatat gtgttcttta cacatagggc atggtagccc attatcacaa acttccctaa
    27061 atttagattc tgttatggta acttttgtac cacaatcgaa acaagtagct tcaattttag
    27121 ttattttacc gatattcata aatcaccacc taatcatata tttataggat ttatcctaca
    27181 aatatagtat atcaaaggag ggaaataatg gcaattaatg acaacataaa taaaatttta
    27241 agagatagaa atttaaaagc gtggaaatta gcaaaagaaa taggcgtaga ttcaggaaat
    27301 ttatatgcaa ttttaagagg agaaaataaa aatccaacta tagatacatt gataaaacta
    27361 gctgactatt tagatgttac attagacgaa ttagttggaa gatagaaatt aaatacagaa
    27421 tattttgaaa gtaggtgtat tgtatggcaa aagcagtagc taaagaacaa ttgttttata
    27481 gggcaaaaga tatagctaag attttagatg tatgtgaagc aaccgcttat aaaataattg
    27541 gagaattaaa taaagaatta gaaaaagaag gttggaagac ctttcctgga agggtatcag
    27601 taacttattt caaagaaaga tattgttata aaacaaaaaa aggggcataa aaaatgctat
    27661 gagagtagct aaagatatgt ttcctaaagt aattgtataa agaggaaggg ggtgatttag
    27721 ttgaatgtaa gagtactgat agcttatata cagttttgta agcaatacaa taagaaagcg
    27781 agttttgaag gtcttaaaaa atacaacaaa ggggtaattg catgagaata atttataaaa
    27841 acaaaatcta caaagtagaa caagacaaag tgttatttag aattacatac tatgatgagc
    27901 agaaaaataa caggaagttt aataacaata agaaagtaaa aagaagtgtt ttaacaagag
    27961 atatagagtt agttaacttg tatttaccag cacatttaaa aataaagtag gaggtttaat
    28021 tgcatatggt atttaattta gagaagttca aagtgggaaa tgcgataaga ataagttgtg
    28081 aaagatttgg ttttgaaatt gattgtattg tagtagtagc aactgaggag gaactaaatt
    28141 tagcttactt tgataaagaa agaggttgca tagagtatca agcattgatg ccagaagacc
    28201 ttagatatga tgattatatt ctcgaaagat taggttagag ggggtgtatt ttaatggaaa
    28261 cagctatatc tattgcaaaa ggtcaaatag aaggagcgaa tgagagtata aaggaattaa
    28321 aatcaaaaga aaattacgat aaagaaagtt taagatggtg ggaaggtgtt aagcaagcta
    28381 gtgaaaatat actagagttt ttagaaatag aaaataaggc ataagaaaag agccattacg
    28441 attggctcaa ttcaaaaaca taataaaatt taattagcta tattatagca caagggggaa
    28501 ctaaaatgaa agcaatttta ttaaaaagtt taaatataga gaatttcaaa gggataaaag
    28561 aacttcgcat agattttaac aacataacta atgtgtttgg agaaaatgca acaggtaaaa
    28621 caagtatatt tgatgccttt acgtgggtaa tgtttgacaa ggatagcaag aatagaagcg
    28681 tatttgagat aaagccttta gacaagcaaa ataaagtcat tagaggactt gtaacaactg
    28741 taacagcagt gctggaagtt aataataaag agataaagtt aacaaagaaa tatgaagaaa
    28801 aatggactag aaaaagagga gaatcagaag caacttttac taaaaacgaa acaacataca
    28861 tgataaatga tactccaata aaaaagagtg aatatgtaaa agaggtagct gaaatagcaa
    28921 acgaggaaca gtttaaatta cttactaatc cgtatttctt ttcgaatgag cttaactgga
    28981 aaaaaggtag agaattaatt ctaaatgtgt gtggagatat aacgacagaa caaattatag
    29041 aatcaaataa agatttaact ttacttatta cagagtttga aaaggaaaat aacatagata
    29101 agattattaa aaatagaaaa gctattaaaa ataacttatc taaagaaaaa gaagaaatac
    29161 cagttcgtgt aaatgagtgc aataaaagca tgtatgacat agattttgag gaaatagagg
    29221 ctcaattaaa agctaaaaag gctgacttag aagctattga ggacatgtta ctaagtggca
    29281 caaaggcgaa tgaacagatt ttaaaagata aagaaaagat atttgagcta aaacaagaga
    29341 cacaaagtat taaacaatca gcaagtgaaa aaggaaataa gaaaaggaat gagctgttaa
    29401 aagaaaagga tgagttgaaa tataatatta aaaacttaag aaataatctt gtttatttag
    29461 aaagggataa tgagttaaaa gaaactttga aaaaaagagc gattgaaaaa acaacaaatt
    29521 taagagataa atggactaaa aagagtcagg aaacattaga tttaagtgtt atccagacag
    29581 aatgcccaac ttgtaaaaga cctcttgatt tagaagatat agaagaaaag aaaaaggaaa
    29641 tgttagataa ttttaatcta aataaagcta aagaattaaa agaaatagca gagctaggga
    29701 aatctaaaaa tgatgatgta gaattattta atacagaaat tgaaagatta aaagtagata
    29761 taaataagac tttagaagag atacaagaaa aagcagtatt attagataaa ataaaaaaag
    29821 aattagaaag tacaaaatct acagagatat attcagcaga tgaggaaaaa agattaacag
    29881 aaattagtgc agaaataaaa gagttagaag aaaaaataaa caataaagat gctgataaaa
    29941 atatagatga gctaaaagaa aataagaaaa aactgactag tgaaattgag ttacttaata
    30001 aagaactagc taaaagagat attaacaaag agttattgga tagaaaagag cagttgttag
    30061 aaaaagaaaa agcgttaggt atagaactag ctcatcaaga gaaaatactc aacttatgtg
    30121 aattatttat aaaaactaaa gttagtttat tagaaagtaa tataagtagt aaatttaaga
    30181 atgtaacatt taaactattt aaagagcaga taaatggtgg tatcgaagaa acttgtgaag
    30241 ctttaataaa cggtgtacct ttcagcaatg ccaacacagc ggggcaaata aacggagggc
    30301 tggatataat aaatacttta tctaatcact ttgaagttaa aatgccaata ttcgtcgaca
    30361 acagggagag tgtgaataat ttgattgata ttgatagcca agtgataaat ttgattgtaa
    30421 gtaatgataa cccattaaaa atagaagggg tgaactaaat ggcagaaaga aatataactg
    30481 atgtagtttt aaatagagtg aatgagctaa aagatagtgg tgagttagta attccaccca
    30541 cttattcagc agtaaatgct ttaaaatctg catacttaat tttacaagaa acacttgata
    30601 agagctataa gcctgtactt gaaacatgta ctcctattag tataatcaat tctcttttga
    30661 acatggtcat acaaggatta agcccagcta aaaaacaatg ttactttgtt gcttatggga
    30721 acaaattgca acttatgaga agttatatgg gtactatagc agttactaaa agactttcta
    30781 atataaaaga tataaaagcg tattgcatct atgagggtga taaattcaaa gtcaaataca
    30841 ataaagaaaa tgctgtacta gaaataggag aatatgaacc agcttttgaa aacatagata
    30901 taggcaaaat aaaaggtgct tttgctgtaa ttgttggtaa tgaaggaatc ttgcataccg
    30961 aaataatgac ctttacacaa attgaaagag catggttaca aggtgttggc tatagtaatc
    31021 ccaaaaataa agtacatgat aattttacag aagaaatggc aaagaaaaca gtaataaata
    31081 gagcgtgcaa gatgtatgca aataccagtg atgatagtga tttattaata ggtgctttta
    31141 atgaaactga tagagtaatc actagcgaag aaattgctaa agatacagac aaagaagtag
    31201 aaaaagagat ttctcaaaat gctaatatca agtctttaga aatgccttca caagtggata
    31261 atacaatctt tactcaaact aaagaaaaag tagctattaa catagatgaa gataagccga
    31321 atctagctga atttgaagaa gcaatccaag ttgaattgga tacaccacca ttttaaatat
    31381 gattaagata ttagggagca gtagcagagg taattgctac ttgctccaac tggaaaacga
    31441 gacattaatt ttagagtgtg gagtcagtta caaagagata ttaaaaggct tagatttcag
    31501 tttagaaaat gttgtaggat gtttggtcac acatgaacat aaagaccact ctaaagctat
    31561 cacagagctt acaaataatg gaatagatgt atattctagc aagggtacat tagaagcttt
    31621 aaaaatagaa aatcatagaa ctaagattat agaaagcgag aaattattca agataggtaa
    31681 ctttaagata gtgccattta atactaagca tgatgcggta gagccattag gatttttaat
    31741 aaatcatagt agttttggta acctattatt tataactgat agttattatt gtgaatacaa
    31801 ctttaataat ttaaatcaca tcatgattga gtgtaactat agtaaagatt tattagataa
    31861 caacaaagat aagatttatt tgagaaatag aatagtcaaa agtcattttg aattaagtaa
    31921 tgtgattaat tttctaaaag taaatgattt aagtaatata aaaacaatta cattgcttca
    31981 tctaagtgaa gataacagtg ataaagattt atttataaga gagatagaaa agaatgtggg
    32041 agtaccagta atagtagctg aaaaaggatt agaaatttat ttagactaga ggtgataaag
    32101 tggcaaaata tagaatttta caagctaact tttgggatga tggatttgta ttagatttaa
    32161 ctcctgaaga aaagtacttt tataactatc ttttaactaa tggtagagca agtcaatgtg
    32221 ggtgttatga attaccctat aaaattatgg aaatgcaaac aggatataac agggaaactg
    32281 tagagaagtt aattaaaagg tttatagagt atggaaaaat aaaatatgac tctactacta
    32341 aagagatatt aataattaat tggagtaaac ataatttttc taaaagtcca aaagtacgta
    32401 cttgtatctt aaaagaggtt gaatcaatta aaaataaaga atttcagcag tatatgtata
    32461 gagtatgtat agactatgga taccctatcg atacagtatc tatagactat ggggaaaaag
    32521 aaaaagaaaa acaaaaagaa aaagaaaaac aaaaagaaaa agaaaaacaa aaagaaaaag
    32581 tagaaccgtt aatttgtgaa gaacaggaaa aaaatgagtt aaaagaattt aagaagctat
    32641 atgaagaaaa tataggagtg gtatatccag ttacagcaga atggttaata gaaatttcta
    32701 gtgatgtaga tataagatta tttaaatctg ctatagagat atgtgctgaa aagatgaata
    32761 tgaatatagc atacttaaaa ggtatcctta aaaagtggaa ggatgcgaat ataactacat
    32821 atgaacaact agaatcatat agattacagc aagaaaataa gaaagcaaaa aaagtagtta
    32881 atggccaact aagtaaaaat aagtttgcca actttgaaca aacatttact aagtatacag
    32941 agaatgagct tgataacata attaagaaaa gtcaagatgc taagttcaaa taaaattaaa
    33001 cttctaggaa gtaaatatca atatattgct tcctagaaag ggggtagaat atgggtaaaa
    33061 tttggatgga tgcaggaaca tttttggaaa ctaaagatat aggagatatt gaatgtaatc
    33121 taagagaaat gataaataaa aataaacaaa aaaatttaat tggtagaata aattccaaag
    33181 gacaaggaag aaaaagtaag aaagtagagt gtactaacat cattactgga gagagtaaaa
    33241 tatttgtcag tgctgtagaa gcaagtgaat atttatattt cacggaactt catattactc
    33301 gtctagcaag aacaggaaag actactaaaa atggttggaa agttagatat attgaagagg
    33361 tgtcaaatgg tattagcaaa tgtggaacaa gtaattaagt tagctgaaaa gatattaagt
    33421 aagaaaaagt gttctgttaa taaagctatt gatatagcta taaaaatatt aaatagatac
    33481 gaatatgagg ggatgattaa atgagtctaa ttgaatatag aggttatgat tttgaaaata
    33541 aaaagtggat ttattctaaa acaataatgt ggagtaatgc agtagactgt ttattaatgc
    33601 tgaaagaaga ttttaaatgg cgaaaagttt gtaatgttgg aatatgttct gaagaatggg
    33661 ctggaaataa tcaagaaatt tttgaagggg atatattaaa agaaaattat aatcctcaca
    33721 atagaagttc atatggaatt gtaaaaagag attttaatag tattaagtta tatttggagt
    33781 ggcattattt aaagaagttt gaaggagaat ggatagagat tatagataaa acagaaatat
    33841 atcatagtag aggttacaaa gtaattggta atgaatatga gaacttagag gaagttagga
    33901 aagagttttt agaacgcaag gagatgttgg aaaatgaacg tcttagctag tttaatactt
    33961 atagtaggaa gttttatagc tggtagggtt tatgagtata gattgaatct aaaagagttt
    34021 gaaaattatg ataatatagg aggttttaag aatgaatgat agattagaaa tgataaatgc
    34081 ttctgtaaat tatatacaga tgatatgtga aagttcaaat atagctatta tagcagagca
    34141 tgaccgagtt agaatattgg atttagaaac taaagaaaag tatgacctat taagaagtga
    34201 gggggattaa aaaatgagta aagttataca atgtgatttc tgtaaggaaa tatttgaaaa
    34261 atataatgga gaatgtattg agctatataa aaaggattgt agcaaagggg tgcttgggat
    34321 agataaacac atatgcccaa cttgttatga aaaattcatt gaaggaaaaa tagagaaagt
    34381 agaaaatgct aaaagattta aggataaatt aatagacttc ttggttgagc atgaggtttg
    34441 tgactgttgt gcttgcgact gtgtgtttga ttctaatgac gaaaaaaaat gcaaggcagg
    34501 aattagagag tgggttgaaa gtgaggtaga agaataatat ggcaaaatta atagttagca
    34561 tacctttaac taaatattta aaagatataa ctaaagaatg gggagaaact tatataacta
    34621 aaacatatgg tgggcatgtc tatttaagtg atgaagctcc aggagaagta tttaaaaaag
    34681 aagatgattt aaattatata gagtttaacg attctgatat tgtcatgaga ttacctaaag
    34741 aagtacatca acatataaat ttgaaaaaag gttgcaacaa gaatcttaaa gatgtattaa
    34801 aagaaataaa aaagatagaa gagaaaacaa atatatagaa aatatctaat taaaacagtt
    34861 tagagagttg caaaatatct tttagtataa atttattgtt gaagtgtttt gtgactctca
    34921 aaaatgaaaa taaggaggag ctatattgct tacattttta gatttattcg cagggatagg
    34981 tggttttagg ctaggaatgg aaaaagcagg acataaatgt ttgggacatt gcgaatatga
    35041 taaattcgca aatttaagtt ataatgccat gcacaaaccg aaggaggatg aatggtttga
    35101 aagagatatt agagaaatta gaacagaaaa tatcccaaga gcagatgtct ggtgttttgg
    35161 attcccatgt caagacattt ctgttgcagg taaacaattt ggatttaaag gaagacgttc
    35221 aagtttattt ttcgcagtta caaaacttat tagagaactc aaagaagaag atagacccaa
    35281 gtatttactt attgaaaacg ttaaaaatct acttagtgtt aatggaggat ttgatttcct
    35341 caaagttctc attgaactgg atgaaatcgg ctatgatgca gagtggcaag ttcttaactc
    35401 taaaaacttc ggagtacccc aaaatagaga acgaatattc gttgttggac attttagagg
    35461 acgaagtaca cgaaaagtat ttcctatcga aagaaaaagt agaaaaaatc ttgaacaact
    35521 aaataatcca actcatagta caagtggagt tttagtcaat gcagttttaa cacccgatag
    35581 ggtaaacaaa agacaaaatg gtcgtagaat taaagaaagc ggagaaccaa tgttcacact
    35641 aacagctcaa gataaacatg gaattttgaa aaatggagat ataagaaggt taacaccaaa
    35701 ggaatgcttt aggttgcaag gatttccgga taaatattac gaaagagcag caagtgtatg
    35761 ctcagatagt caactgtaca aacaagcggg aaatgctgtt actgcaaatg ttgtatatga
    35821 aatagcaaaa agaatgggct aagagttgca aaatgtcttt tagtatgagt attgttgaag
    35881 tgttttgtaa ctctcaaaaa tgaaaataag gggtgaataa atgtcaaagt atgtgcttag
    35941 atggcaaaaa gggttattgt tggatgaacg taagataaat tattcatgtg gaagtaaaga
    36001 aatgctaaaa caaaaagcag aattattagc taaagatgac aagatattgc ttgtaacaat
    36061 agataaagtt gaagaagtta taaaagatac tagaagtcaa aaaatggctg aatattattg
    36121 tgatggagga attgaaatat gataatacac aaatttataa tacatgtttt agataagaat
    36181 agcgatacac caatactaaa tgattttgag ggtagggtta gtcaagatat tgaagctttc
    36241 tttcaaaaga aaataagcaa agtatcaaga gataatgaca tcagaacagt agtatttaat
    36301 gactatagta acaatctaat taagaagtgt tgtgaacaaa ttatttatga tgaaagttca
    36361 tttttaaata actctaaaga gattgcagct tatttatttg atgttatgaa attgaatgct
    36421 atattagaat cttgcgactt agcaatttgc ttatactctc aaaaagatga aaagaaagtt
    36481 gctatattaa agcttgatta caataattcg tatactcatt ctattagctt tgaagaggat
    36541 aaatttaata tacagatgtc taagaatgaa attaatatac aagagactaa gacggttaaa
    36601 attgctgctt tggttggatt gagtggaatg aatgacgaat atcatctaaa agtattggat
    36661 aaggatgcag agaaggaaga agctaattct aagtttgtta cagagtttct aaatgctact
    36721 aaagtgaaag atgacaagta taggactaaa aagtttaaag atacagttga aaattggata
    36781 actaatgttc ttggaaatga tataaaacaa gctgaggaca taagaagtat attaaattat
    36841 actttgaaag aaaagcatga aattgatata aaagattttg ttgataaatc aattaaagat
    36901 gatgagttaa aaaatagttt taaagaacat atggaagaaa agggtcttga tgaaagtttt
    36961 agcatagata aaaaatgggt tgaaaaaaag cttaaaaaga gaaatataaa aactgacaat
    37021 ggttttgaaa taaaaggtaa cttaactgat tttgaggacc caatgaaata tacagtaaga
    37081 caaaatcaaa atgggtctat agatataatt attaagaatg ttaatttcta taatgaaaaa
    37141 taagggggct acaatggaaa ataaagataa ttttgtatta aataagcttg gaccagcaag
    37201 taaagtaatg aaaaaagttg aaatagatga aaaagaaatt aagagttatc taaaagaact
    37261 aaaagaatgt gaagaagtaa aagtttttat tattagaaaa gatggaattg aaattccaat
    37321 agttttcaaa gatggaaata tgaacgaatg gttaagaaaa gaaattgaga taagttttga
    37381 tagatttaag gatgaaattg ctcaagttaa aaaagcattg attaaagtta caggagagaa
    37441 ttaagaagtt agaaggtgct catatgacta ataaagaaat gtgcaagtca aataatcttg
    37501 atgaaagaga agtgtgtaag gaatttggaa aagagatttg tggtagttgt ataaatgata
    37561 gggtagattg cgaaagcaaa gattgtgata tagcatatga aaattggcta gagaagaata
    37621 cagaaagata attataaaaa taaagtcaag gtaagtttgt gaatgaaact agaatgttat
    37681 agacttactt tgacttataa aaaaggagtg tattaaatgg ctaatatata ttgcgaaaat
    37741 tataattgta aaaactactt tgaagatatg tgtatgcttg aaagaattga aattaataac
    37801 ctgaaagtgt gtgaaagtta cattgaaggt aaaaatgagc tatataaatt agaaaacgga
    37861 tatactatac atcctaaaga tttgaaaatg gtgaaaagta aagattattc tgttgaagtt
    37921 actcatattc caactggtat tacagtaaaa tgccgttcta caaatagtat tttaaaaaat
    37981 aaaaataagt gtttggaagt tctagaagaa gaattaataa aaataaactc tcacttagag
    38041 ctagaagatt taaactaaat aggaagtgag cttatgaaac gaagaagatg cagttggtgt
    38101 ggtaagctat tttatcttaa ggaaaaatct aaggatgttt attgttgtaa agaatgtagg
    38161 aagaaggcta agaaggtgaa aaaatgaaag tttttcttgt aatagatgga gagccagttg
    38221 gcaaggaaag accaagaatg aatacttacg ctaaaaggac ctatacacct aataagacta
    38281 agaattatga ggacctaata aaatggctat atcaatctaa agttaaatat tactttgaag
    38341 gttatataaa aatgacttta agatgttatt attctatagc taaaagtaac agtaaaaagg
    38401 ttaaggagca gaaaagaaat aatgtgttaa gacctagtaa aaagcctgac attgataatg
    38461 tcattaaagt agtagctgat tcactcaatg agatagctta taaggatgat acacagattg
    38521 ttgaggttgt agctagtaaa tattacagtg ataaaccaag agttgaggtt atattagaag
    38581 atgttattta accaacggaa aaatccgttc gttagattag gtactcagtt tttcataaaa
    38641 atgtgaaaaa gctgaataga gaatatatca aatggtaaag gagagataaa ttatgaatga
    38701 aaatataaat aaagaaataa cagtacttgg aactttagaa atcgagggaa tgaaatttca
    38761 taacattgag ggtggatttg gagaacataa gaaagcaatg ctagtaaaag atatagctga
    38821 gatacataat agagaactta aacatataaa tgagctaatt aataataata taaagagatt
    38881 taaaacaaat atagatatta tagatttaaa agtgagtcgt tctgagcgac taggtgattt
    38941 aaaggctaat ccttttgaag gattaggtta cgaggatgtt ggatatagta aacaatcttt
    39001 taatcagtca agaaatattt acttgttatc tgaaagaggt tattcaaaac tactaaagat
    39061 attagaagat gataaggctt gggaacaata cgagaaaata gttgatggat atttctctat
    39121 gagaaaagag ttaaataacc ctcttttaag tgcatcgaag gagttacagg ctatatttat
    39181 gctagataag aaacaagaag tcttagaaac taaaatagag aatgttaatg agaagttaga
    39241 gaactttatg gatgatgcac cattattcaa tatcgagtgt gagtgtattg ttaaagaggt
    39301 taagagagta gcaacaaaat cacttggtgg acatggaagt aaggcttata aaaataaatc
    39361 tttaagaggt aaagtttata gtgatatata ccatcagatt aaacgagaat ttggagtaga
    39421 tagttataag gctataaagc gttgtcagtt agataaagta ttagagattg taaataatta
    39481 taagttacct atagtgtttg aagaagaaat aagacttttg aatagtcaat tatcaattgt
    39541 gagttaagac aggaatagat ttttctcctt taaaggggaa aacctgcaat agttaattaa
    39601 aagagaaaag gagtgctttc acactccact tgtcaaaaat ataaaacttt tatatacaag
    39661 attattataa cataaataat tgataggagt gtgtgagtat gtctaaaact aaaaaagagt
    39721 tttttaatgc aactaagaaa caactttcta attataaaca attaagtgca aatataataa
    39781 aattaaaaaa tgaaatacaa atgttgaaag ataattcggt tggagattta atgaaaggta
    39841 taagttatga tagtgtcaaa acaggaaaaa caaacaaaac tagtaacatg attgaggatg
    39901 ctattgttaa tgtatcagac ttaataacag aaaaggaaat agagttatat gaagcagaaa
    39961 taattaaatc cacaatagat ttagctataa gaaacttaaa acctatacac agacaaatta
    40021 ttgaacttaa atatatagat ggtctaatgt ggcaagaaat ggttgatata gtacatttag
    40081 aagaaagaca attaagtgta agagctagtc aagctattag ctcaatatca atagcattat
    40141 ttgggaagaa agcattaata gagcaagaac cactttttga attgttagat tacaaactaa
    40201 attaaaaaag taagagtaat tttgagtgct gaaaatgtgc aggttttttt gttttagaca
    40261 tgagataata gtattgtgga aatgaatatt tctctctcaa aactaaatat atatgtgggc
    40321 taggtaaagg gattcaccta gcttatatga acagactagg cagggcgtga ggacgctgtt
    40381 agttcaattc taactatgtt caatctttag tttttctatt tcaattaatc tacggataca
    40441 ctaaaaaata gtatttgaat tgagattaaa atctcataca gttttgtatc ttaattcaga
    40501 gtctaaaccg agtggggctt ggtaacctca ctcaccatgc aggtactggt gtttaatcta
    40561 agttcgattc ttagaacttg cgacataata tatgtatctc cctatttaaa aaggctaagt
    40621 gagggtaagc ttagtctttt aatttaaaaa aaaaagaaat ttttattgtc ataatactat
    40681 ttgcttaggt atattataat gtgcatactt aaaattaaat acttagcaag catttgaatt
    40741 aatatacata aaatatatga cataattttt tatagtgtaa gttatttaaa ttaatataaa
    40801 taacagtaat tttattatag aaaatgtata tattgtgaat aataataata ataaaatctt
    40861 gtacaaaatg ccaactgata attcctcgaa atgtattgtg tatttaacgt tacgattgta
    40921 taattaactt ataatagtga tatggaaggt ggtacttatg gctacaaaaa gtattttaaa
    40981 aaatgtagat gtaagaaaaa aggcatttgg aagaaatcta gtatcagctc tagaaaatgc
    41041 taaaaataaa caagaaaaag aagttgtatt aagtaaaaaa tgttcagaag taccaaaaga
    41101 taaaataaag gatatattcg ggagatttta atgagtggct atttaattgt aaacttaagt
    41161 aatatgctgg gagaactgga ggaagaagaa gttaaaaaaa ttctctccag tttttcttgt
    41221 cctcttaata aagatgtaga agacttttta aaaaacaaag ctattgaatt ttctaaacag
    41281 ggtttagcta gtacacattt agtattaact tcttataaag gcaagcctgt tatagttgga
    41341 tatttcactc tagctaataa gtattttaca ataaaaagaa aaacattaac aaactcttta
    41401 gctagaaaag tagtaaagtt tggacaatat aatgaagaac taagaagata tattattgga
    41461 gcacctttga taggacaaat aggaaaaaat tattcaaata attataataa attaattaaa
    41521 ggtgatgaac ttctaaaaat tgcatgtgac aagataaaag cagtgcagtt agatatgggt
    41581 gggaaaatag tatatcttga atgtgaagac aaacctaagt taattgaatt ttataaggat
    41641 aatggatttg tagattttgg taaaagaagt cttgataaag atgaaacaga ttcattggat
    41701 ggggactatc tagtccaaat gttaaaatat ctaaaaaaat aaaagtacat aaaatctaaa
    41761 atgactatct tgatggatgg tcttttttta tacaataaat taaaaggaga attatagaat
    41821 gaaaaagata actaaactta tattatgttc tttgctagta atcagtatag cgagtccatt
    41881 acaagttgaa gctaaaacta ctcatcattc cagttcgcat gtttctattc ataagagtag
    41941 tacaaaatct aaaagtagta gacctaaaat tactaaaact aaaaaagcta ctaaaacata
    42001 tagaactaac aaatctatca aaaagaaaat aaaacttaaa aaacaagtaa acaaaaaaac
    42061 tcaagttcca aataaacaag ctgctagaaa agacaaaaaa acaactacat ataattatta
    42121 caatagctat aactcaaata gatactatac tacttcaagt agcgggttaa gtttctggga
    42181 ttgctatatg ttaggtcatt tattcaataa caacaataaa gtttcagagc aagatatagc
    42241 tagagagttg caaaaacaag gttatagtaa acaggaaact gataatatat taagaaaagc
    42301 aaatcaaaat caagctaaaa aagaagaaaa gaaaaaaaga gtgatgatgt taatattctc
    42361 tgtattagga gcattgttca ttataggttt agggctaata atatttatca aaagggaatc
    42421 aaaaggttgc aataaatcaa tgtaatttaa ttagatacat agactctaac aagagttctt
    42481 ttttattccc aaaacgacaa acaaacgagg tggtggtatg aatgaaaagg cagatttagc
    42541 ccatgaagat tacttaaaag ggcttaagta caaggaaata gctgaaaagc ataatgtaag
    42601 tttatcgact gtaaaatcat gggcaactag atactggaaa caaaaaggtt gcaaccaatc
    42661 aaaaaaagtt gcaaccaaaa agagaggtgc acccataggt aataaaaatg ctactggtcc
    42721 accaggtaat aaaaatgctg aaaagtttgg tttcttctca aagtatctac ctgaagaaac
    42781 tagggaattg atgcaagaaa tatctataaa agataaattc gatattcttt gggaacagat
    42841 aacaattcaa tatgcagcaa taataagagc acaaaagata atgtatgtta aagacaagga
    42901 agaaatgatt aaagaattaa agaaacatga aagtacagaa aatggagaga agatagagta
    42961 tgaatttcaa tttgcatggg ataggcaagc atcttttctt aatgcacaga gtagagctat
    43021 gagtgaatta agaagtttaa ttaaacagta tgatgaaatg attcataagg attggaattt
    43081 ggctacagag gagcagaaaa caagagttga gaagttgaaa tgtgaagttg ataacctaag
    43141 taaagatgac attggagatg atgagttgaa aataagtgta gattatggtg atagaaatga
    43201 tagttagagt aaattttaat ccagatttca aggaagccaa ttttactaaa aaaagataca
    43261 gagcaatgaa aggttcagca gggagtggaa aatctgttaa tgtagcacaa gactatatac
    43321 taaagttagg agataagaag tatcaaggag ctaatctatt agtagttaga aagtcagaag
    43381 ctacacataa gtattcaacg tatgcagagc ttacaggagc tataaatcgt atttatggta
    43441 aacaagctga taagtattgg aaaactactt taaatccttt agaaattaag agtaaagtta
    43501 ctggtaactc tataattttc agaggagtta atgatgcaaa acaaagagaa aaattaaaat
    43561 caattaactt ctcgaaagga aaattaacat gggtttggtg tgaagaagct acagaactta
    43621 tggaaagtga catagatata ctagacgacc gtttaagagg tattttaact aatcctaacc
    43681 tatactatca aatgacattt acatttaatc cagtctcatc tactcattgg ataaaaagaa
    43741 agtattttga ctataaaaat gatgatatat ttactcatca tagtacttat ctacaaaata
    43801 gattcataga tgaggcttac tacagaagaa tgcaaatgag aaaagagcaa gaccccgaag
    43861 ggtacaaagt ctatggtctt ggagaatggg gagaaactgg tggagcaata cttaaaaact
    43921 atgttataca tgaatttcct acggaatttg aatactttga taatatgaga ctgtcacaag
    43981 actttggctt taatcatgca aatgtagtac tcagaattgg ttttaaggat ggagagttat
    44041 atatatgtaa tgaaatatat gtacatgaaa tggatacatc tgaaataata aagattgcaa
    44101 acagtaaagg tttagaaaag aatatattta tgtactgtga tagtgctgaa ccagatagaa
    44161 ttaagatgtg gaagagtgca ggatataaag ctaaaggagt taaaaaagga ccaggaagtg
    44221 ttaaagctca aatagattat ttgaaacaat taagaataca tgtacatcct agttgcacta
    44281 ataccataaa agaaatacaa caatggaaat ggaaacaaga tgaaagaact ggattatatc
    44341 ttgatgaacc agttgagttt atggatgatg caatggctgc tcttagatat tctatagata
    44401 ataagcttaa aaataatgga ataagcttct taaagtaaag gaggcgttaa atatttatat
    44461 aagtgaaaca gatttaataa aagttcagtt aaaaaaagag agcacattta acctagtaaa
    44521 agttatagag cattatattt taaaacatag accagagaaa tataaacaag gtgaagaata
    44581 ctattatggc aatgcagata taaacaataa gagaagatat tatctcttag atggagctaa
    44641 ggttgatgat tttactaaag ttaataataa agcaattaac aactaccata agcttttagt
    44701 tgaccaaaag gtaggctata gtgtcggaaa tcccatagta tttaatgcag atgatgataa
    44761 tctcactaag cttttaaatg acttactagg agaagagttt gacgatacaa taacagaact
    44821 atatctcaat gctagtaata aaggggttga atggttacat ccatatatta atagaaaagg
    44881 tgagtttaaa tatgtaataa ttccagctga agaagcaatt cctatttggg atagtaaaag
    44941 acagagggaa ttagttgcat ttattaggtt ttattatatt gaagatatag atggaaataa
    45001 aataaaaaga gttgagtact acacagaaaa tgacgtaact tactttattg aaagaggtaa
    45061 tagttttatt caagaatttt tatatgatga atatggaaaa atgactgata tacaagaagg
    45121 tcattttaga ataaataaca aagaacaggg atggggtaaa gttccattta taccttttaa
    45181 aaataatgaa aagtgtgtct cagatttaac tttctataaa tcattaatag atatatatga
    45241 caataatatt tctacactag cagataactt agatgaaata caagaggtta tttatgtatt
    45301 aaaagaatat ccaggaacaa gtctacaaga gtttatagat aatataagat actataaatc
    45361 aattaaagta gatggtggag gtggagttga taaactagag ataaatatac cagttgaagc
    45421 taaaaaggag cttcttgata gattggaaaa gaatataatt atctttggtc aaggagttaa
    45481 tccagaatct caaaacacag gtgacaaatc gggtgtagca cttaaatttt tatattcact
    45541 acttgactta aaatgttcta agactgaaaa gaagtttaaa aaagcaatta gagagctttt
    45601 atggtttgtg tgtgagtatt taaagataag tggtaataag agctatgatt ataaaacagt
    45661 tcaaattact tttaatcact ctatgataat aaatgaagct gaaaagatag atatggcagc
    45721 taaatcaact ggaattgtat cagatgaaac tattgtttct aaccatcctt gggtcgagga
    45781 tgttaatgac gaacttgaga gacttaaaaa acaggaagat actcaaaaag agtatgatga
    45841 tttaattcct aataatcaag atggtgttat agatgaaaca taaagattat tggaggaaga
    45901 gatttgaaca attagaagaa gctcagaata ataaaagtat aaaatattat cttgaattag
    45961 aaaaacaata taaactagca atgtctaata tagaaaaaga tatacttata tggtataaca
    46021 gattcactga aaatgaggga atatctttat tggaagctaa gaaactgcta aatacaagag
    46081 aactagaaga gtttaaatgg agtgtagaag aatatattaa atatggtaaa gaaaatgcta
    46141 taaatcaaaa gtggatgaaa gagttagaaa atgctagtgc aagagttcat ataacaaggc
    46201 ttgaagcttt aaaactgcaa atacagcaac aagtagaagt tttatatgga aatgaacttg
    46261 atggtattga taaactaatg agagatattt atacaagtgg atactatcat acagctttta
    46321 atgttcaaca aggagtaaac gttggttgga gtttaatgag tcttgatact aacagaataa
    46381 ataaagttat ttctaagcct tggactagtg atggattaaa ctttagtgaa agaatttggg
    46441 gtaagcatag acctgcttta atcaatgagt tacatactaa gctaactcaa tcaattatta
    46501 gaggtgaaaa tccaaaagtt ttggtaaatg aattttctaa gaagtttaat gtatctaaat
    46561 cacaagctaa gaatttaata atgactgaat cagctttctt tgcatcagct tcaagaaaag
    46621 attgttttaa tgatttagat gtagaaaagt atgagattat tgccacacta gatttaaaaa
    46681 catcaaatat atgcagagag ttagatggaa aagtatttga tatgaaagat tatcaagttg
    46741 gaataacagc tccaccattt cattgtcatt gcaggacaac aacagctcct tggttcgagg
    46801 atgaagaagg ttatagagca gcaagagatg aaaatgggaa aacatattat gtgccatctg
    46861 gtatgaaata taaagaatgg tatgaaaaga catttataac tgataaaaaa gatgatatac
    46921 taagtaataa gagttggtta aaagcagatt tcccaactga aaagaaattt aaaaagcatg
    46981 tagaaaaaca cttaaatgaa tatggaaata taactgctga agaatattta tctactgcaa
    47041 gaaatttgtt atcagagcaa ttaagtaatg atgtagaagg atttttaagt aaagataact
    47101 ttttatttaa atatagaaag agtactaatg attttgctgt tggaagagct gatggtaaaa
    47161 tatcaacctt atttaagcca aaagaaggtt ataattactg gctagaacaa ataaaagaat
    47221 ataaggaggt ttagacatga attgtccagt atgtggtaaa gatgtagatg tatttgatat
    47281 ttgtgataat tgtaattggc aaaacagtgg accaaaagaa actaattaca aaggaccaaa
    47341 taaaatgtca ttaaaagaag ctaaagaggc ttatgaaaaa ggtaaaaaag taatataaaa
    47401 gcacttgcta agttataaat tagtaggtgc ttttattatg taaaaattta ttgcgagggt
    47461 gatttgaaat gcttaaatta tatctatact tattttatca ataattgtgt tttgtacagg
    47521 gctttattta ttcaacatga aggttgatag taatgaggaa ttaattgaat tacttaaaag
    47581 taagaatatc agaagaagaa aaaaatataa ttttattttc ccagcgttat ttccactgct
    47641 taattttatt ttaggtgtga tactgatact atttttttta ctagttagca atgaagatat
    47701 gattaaaaat ttaaaggggg ataaataata tggctaaatt taaaaagaaa tcagaggaag
    47761 tagaagcttt taaatggata ttaggaagtc ctaatactcc tatatggttt tatcaagctt
    47821 ttgagaaggg aactatatgg cttgatgaat ctttaaactc tgtgaatcgt aaaggtgaag
    47881 taaagaaaac tatctgtata aaatataaaa atggagttat tagggcaact aatggagatt
    47941 ggattataaa agatagtgaa ggtaaaattt attcttgtac atgtgatgaa tttgaaaagt
    48001 actataagga tttggataat gaaacaaaga tttctaatgg aggattggaa tgtttaagag
    48061 agatagcatt aaaagatgtg aattttaaat ttgaactcac aggaattaag gaggaaaaat
    48121 aaatgtttta tctgttgtta caagtaataa gtatatgttt aagtattaca gtatttatgt
    48181 atgttacagg taatatagtc tttaaaatct atcttaaaag tttaagaaaa gaatatgagt
    48241 ctaatataca cgaagtttct gatgaaattt taaagagaat aagaaaagaa ttaaataaat
    48301 cattagatga aagtctttaa gaagtttttt attaggtaga aaacaaaagg aggtttctgt
    48361 tattgaaaga atatatgatt tggtttaaaa gcggcaatag catatctgga atagtagacg
    48421 aagatgttgc tgataagtta atgcaagatt ttatggaagc tgactcagat tgtaaggact
    48481 tgaaagtata tttagatgaa gatggaacaa cagtaataga tttatcacaa atagaagcta
    48541 tatcaataaa taattgtaat gagaataata atattggttt tagtaagtcc tagatagggc
    48601 ttttttattt tgtaaaaaat gaaaggagat atttaaaatg gattggttaa aagaattgct
    48661 agaaggaata aaagtagagg ataacaaaat tgatgtagct tctcttcaaa aatctataga
    48721 aaagaaaata aaagagacta caattactaa agaagattat acaaatcttg aaacacaact
    48781 taatacagct aatgaaacta ttaaaaagtt tgaaggaggt atgacaaaag aagatgtaga
    48841 gaatctaaaa acaacttatg aaactgataa gaaaactttg gaagaaacct acaaaaaaga
    48901 aattgaagaa aaggacttta attactggtt aaatgatgct tttaagtcta ttaaatgtag
    48961 ggatgaaata gcgttaaaag ctcatttaga tatagaagca ctaagaaata gtaaagatag
    49021 acaaaaagct tttgaagagc aaataaaccc tttgaaacag gataaagatt atttgtttaa
    49081 tgcaacacta gaaggtgaag agcctaaaat agatactata acaccagggc aagagcctaa
    49141 gataaatgat tttggtttta attttactgg ggtaagacct catgaaaata ataataaata
    49201 ggaggaaata aaatggcagc actaaattat gcaaaagaat attcaaatgt tttagcacaa
    49261 gcatatcctt atactttaaa cttcggggat ttgtatgcaa caccaaataa tggaagatat
    49321 agatggactg gttctaaaac aatagaaata ccaactatat ctacaactgg aagagtagat
    49381 tcaaacagag atacaatagc agtagctcaa agaaactatg ataatgcttg ggaacctaag
    49441 gtattaacta atcaaaggaa atggtcaacg ttggttcatc cagcagatat aaaccaaact
    49501 aattatgtgg cttcaatagg caatataaca aaagtatata atgaggaaca aaagtttcca
    49561 gagatggatg cttactgtat atctaaaata tatgctgatt ggaccgcatt aggtaacaca
    49621 gcagatacaa ctgttcttac aacaacaaac gtattagaag tatttgataa gttaatggaa
    49681 aaaatgacag aagctagagt acctgaaaat ggaagaatat tgtatgttac tccagtagta
    49741 aatacactta tcaaaaatgc aaaagagata caaagaacag taaatataaa ggatgcagga
    49801 acttctctta atcgtcaaac aactgatatt gacacagtta aaataattaa agtaccatct
    49861 aatctaatga aaactgcata tgattttaca actggatgga aagtaggagc aggagctaaa
    49921 caaatcttta tgtccttagt tcacccaagt gcaataatta cacctgtttc ttatcagttc
    49981 tctaagttag acgaaccaac agcagttaca gaaggaaaat acttctactt tgaagaaagt
    50041 tttgaggatg tatttatatt aaataaaaaa gctgatgcaa tacaatttgt tgttgaagga
    50101 gctggagcat aatggcacaa gtaagaaaat taaatagaat attaactata gaagaatgta
    50161 aaatagatga tttcttagag atgggatatg atttgataga tgaaactggt aaggcagtaa
    50221 agtatggcaa gtcattaaat gtaaaagatt taatagctga aaataatatt ttaaggtcaa
    50281 aagttgagtc tttagaagaa gaaaataaac agcttaaaga gaaaaataaa cttactaaaa
    50341 agtaggtgaa aattatggga aataatataa ttgatgatat agaaaaaaga cttgaaagtt
    50401 ttggatatat attaaaagat ggggataagt ggttaataga ttttgtaaga gaaaaaatag
    50461 aaaatattat taaactagat tgtaatataa aaactatgcc aattgaattg aaagaaattg
    50521 aagttgatat gatagttgga gagttcttat ttaccaagaa aaatatgggg caattagata
    50581 tagaaagcat taactttgaa gctgtagaaa agtctatatc agaaggtgat acaaaggtag
    50641 attttgctat aggaagtggc tctcaaacac cagaacaacg ctttgatagc ttagtagctt
    50701 atcttactac ttatggtaag aataatatat taacctttag gtgcttaaga tggtaagtaa
    50761 aactagaaaa gcaatagaaa tgttatatag agataaatgt actatagttg agtatcagcc
    50821 aattaaagac cctgtaacaa aacgaactaa caataaagaa gtgattgtat tagaaaatca
    50881 accatgtaaa ctttcatata aaaatatagt ttctgctaca gaagggaaag tagctaagct
    50941 agagcaaact attaaactct ttatatctcc agatatagaa attaaagcag gttcaaaact
    51001 tattataaat gataaagagt atgtaagaag tggagaatca gctatatatc caaatcatca
    51061 agaaataata cttgagttat ttaaggataa agcataatgg ctagatgggg cagtgttgat
    51121 tttagagagt ttaaaagagt ttgtaaaaag atggaggagc ttacaaagat tgatttagat
    51181 aagttttgca aggatgcagc aagagaatta gcagcacgat tacttgggaa agtaattaga
    51241 agaacaccag ttgatacagg attcttacga caaggatgga atggagtggc ttatgctagg
    51301 tcgcttcctg tgtataaaca aggaaataat tatattatag aggttgttaa tccgaccaca
    51361 tatgcaagtt atgttgaata tggccataga actaaagatg gaaaaggttg ggttaaagga
    51421 caacatttct taacaatttc agagatggaa ctacaaagcc aagttgataa gattatagag
    51481 aaaaaactat taatattgct taaaggagta tttgatgctt aataatataa ttgatggaat
    51541 atctattaaa ttagataaaa catttggaga gagttataca atttatagtg aagatgtgga
    51601 gcaaggtata aatgaacctt gtttttttat tgttccttta aatccaagca agacaccata
    51661 tccaagcggg agagaattaa agaaaaattc ttttgatgta cattatttcc ctcgttcaga
    51721 agctaagaat tttgaaataa atgagatagc tgagatgcta ctggaggaat tagagtatat
    51781 agaaattgat ggagatttag tcagaggtac aaatatgaat tttgaaatta tagacaatgt
    51841 tcttcacttc tttgttgatt ataactattt tactataaaa aataatgata ccaataagat
    51901 ggatacagta gagttattcg gtggtttgaa gagaggtgat aattttgaat aaaacattaa
    51961 gcaaagaaga tgactacaag tttactaagg agcaaatagt taattctaag aagtatgtaa
    52021 atagaaaaga cttattaaat gcaattttaa aagaaaatga gttatattcc ttctcagagg
    52081 tagaggaaat aataaataaa tttatgaaag gagtgagcta gatggcgtta ggtggaggaa
    52141 catttgtaac acagaataaa atattaccag gtagctatat aaattttatc tcagctaaga
    52201 gggcaaccag ttcattatcg gatagaggta ttgttgcaat acctttagag ttagattggg
    52261 gcatagatga agacgtattt caagtaacca gtgatgattt tgagaagtat tcagtgaagt
    52321 atttcggata tgattatact catgagaagc tgaaaggttt gagagattta ttcaaaaata
    52381 taaggttggg atatttttat aaattaaata aaggcgttaa agccagttgt actatagcca
    52441 cagcaaaata tagtggtatc agaggaaatg acttaaaagt aacagttaca acaaatatag
    52501 atgataatgc taagtttgat gttgtaacac ttttagataa taagaaggta gatactcaaa
    52561 tagctaaagt gattacagac ttacaagata atgactatat cacttggaag aaggatgcaa
    52621 cactagaagc aagtgcaggg ctggtattta ctggtggaac taatggcgaa gctgtgacag
    52681 gagcagagta ccaagctttc ttggataaaa tagaaagcta tagctttaat gctttaggat
    52741 gtttggctac aacaacagag attaaaagtt tatttgtaga atttacaaag agaatgagag
    52801 ataaggtagg agcaaagttt caaacagtac tatataagaa aagtgatgca gattatgaag
    52861 gtgtagtgtc tgtagaaaat aagattaaag ataaagattt agttgaatct agcttgattt
    52921 attgggctac tggagctata gcaggatgcg atataaataa atctaatact aataaaaagt
    52981 atgatggtga gtttgatgtt ggtgtaaatt acactcaaat acaacttgaa gaagcactaa
    53041 agagtggtaa atttatattt cataaagttg gtgatgaagt tcatgtgtta gaggacataa
    53101 atacttttgt atcatttaca gatgataaaa atgacgattt ttcaagtaac caaagtgtta
    53161 gagtacttga ccaaattgct aatgatatag cgactttatt taatacaaag tacttgggtg
    53221 aagtaccaaa tgataaatct ggtcgtatct cgttttggaa tgatgtagtt aagcatcatg
    53281 aacaactgca aaatatgaga gcaatagaag atttcaaagc tgatgatgtt tctgtagaac
    53341 ctggaagcga caagaagact gttgtagtaa gtgatgctgt aaaagttatt agtgctatga
    53401 gtaagcttta tatgactgtt tcagttagtt aacaataaga aaggagaata ataatggcac
    53461 aacaaataaa agcaagagat acaataagtg catctaaggc agagtgtttt gtaactataa
    53521 aaggtaaaag atataatttt atgcaagcta ttaacttaga agctaaaatg gaaaagaata
    53581 agagtgagat acctatatta ggtagtacta caaaaggaaa taaatcaaca ggaagtaaat
    53641 attcaggaaa tgcaacattt tattataata cctctatatt tagagaattg ttgtatgagt
    53701 ataaagaaac tggtgaggat atttacttcg atatacaaat taccaatgaa gacccaacaa
    53761 gttcagtggg tcgtcaaact ataatactgg aagattgcaa tatggactca ggcataattg
    53821 ctaaatttga tgctgatggg gagtatttag atgaagatat ggattttact tttgagaatt
    53881 ggaaattagt tgagaaattt aatatagcaa atggtatgga gtaaaataca catttatgat
    53941 ttatgtatgt gtatttttta tttataagaa taggagatga ttaaaattaa ggataaatat
    54001 gagataaaag attcaatttc ttttgattat agcaataaaa gacctttgga agaacgtgtc
    54061 agcgagatgt ataaaaaggc aggaaaatat cttatagata tttcagataa gttagcaaca
    54121 gatacaattg atggttcgtc attaaagcca ataatcataa aatttgaaat aaatgaagct
    54181 ggtgttgcaa caatagaaaa acaaacaaaa tatttggtga tggaggtaga ataagaatat
    54241 gggagattta aacgcttttt taagtcaaaa tgcaataaaa gtagagaata gaaagtatgt
    54301 ggcaagtgaa aggtttatag gagaagatgg aaaagcaatc gaatgggaac ttaaagcaat
    54361 agattcagat agggacagac aattaagaaa agattcaact ataagagtac ctatattaaa
    54421 taaaaaaggg aaagctacag gacaatacac tagtgaaaca gattttaata cttacacttt
    54481 gaaattatgt gtggaaacta tagtatttcc ggatttacat gatgcagaat tacaaaatag
    54541 ttatggtgta atgggtgcag aggagttatt aacaacaatg ttgactcctg gcgaatatac
    54601 agacctttca agtgaggtag gagaggtaaa tggttttgat agaacttttg aagataaagt
    54661 agaagaagca aaaaactaat ttatgaaggt gattatgatt ctaatatagc tcattattgc
    54721 cttcataagt ttaaatggaa accgcatgaa tatatggatt taccagttga tgaaaaagca
    54781 tttgttgctg cttctataga tatcaaagta gaagaagaaa aagaagaagc taaaaaagct
    54841 gacaaagatg caaagagagg tagaagaaga taatctctgg tgtaaaaatt ttactaatat
    54901 agtataatat atttaaaaat tgtactgggg gattaaataa atgggattgt ttagtaaaaa
    54961 gaataagaaa ccttgttgta tttgcggaag cgaaaaagga cttatgccat ctatagaagg
    55021 tgaaaatttt tgtacagctt gtaattgcaa gtacatagat ttctctgaaa atattttaaa
    55081 agtaactagt attatgaaaa tgatgtcaaa ctcagaagga atgaaaaagt ttatagaagt
    55141 tgaaaagaaa aatttaaaat tgttagagaa gttcaccgag acaaaaagta taaattcttc
    55201 aatttctttt gatgaagagc aaaatctttt aaaaatatca tataaaaata gaaatcaaat
    55261 attagtagag aaaataataa aatttgatga tatattagaa tttgaacttt tggaagatgg
    55321 agaaactata gttaaaggtg gtttaggtcg tgctataact ggaggagtct tattcggagg
    55381 tacaggggct gtagttggag gaattacagg taaaaaaaca agtagaaaag ttgtagaaat
    55441 atttaaaata aaaataactg taaaggacat aaataatcca attgaatata taaatttaat
    55501 taatagtaaa gtaaaaacaa actcttctat ttatcagaaa gctttttctg atgctcaaga
    55561 aatattatca atactatcaa taattacaaa atataatgta atggaagaca aaaaaaagtc
    55621 tatatctagt tctacagctg atgaaatatt aaaatataag aatttgttag atatggaagc
    55681 tattacacaa gaagaatttg atgctaagaa aaaagaattg ctaaatttat aatatataag
    55741 cacttactta aaaataagta agtgcttata ttatgttaaa aaagaaagga ggttaaaaat
    55801 ggcaactata caaacatcta tccgaatttt cgacggaatg acacctgctt ttagacacat
    55861 gaataatgct atgaatattg tattaagttc attcgagcaa ttacaaagaa catctagcaa
    55921 tgctatagat gctaatagta ttagaacagc tagagaagaa ctagcacgtg cagaagctgg
    55981 ctttgataga ctagaacaac aaataagaga atcagataat caacagcgaa ggcttaatga
    56041 ggatataaat aagggtgcaa gttctacaga tagattagtt ggaagtgcaa agaagctagc
    56101 agcaacctac ttaggtataa gaacgttagg aggtctagga aatttaagcg accagatgac
    56161 aagtactaac gcgagactta gtatgataaa tgatggtcaa ctctcagatg gaggattaaa
    56221 taagatgatt ttccaatctg ctgaaaggtc tcgtgcatct tacttagata ctgcaaaaat
    56281 agtttcacga ataggcatga acgcaggtaa ggcgtttagc agtacaaaag aaattgtagg
    56341 ttttgcagag caactaaata aaaagttcgt aattgctgga gcaagtactg aggaaatgaa
    56401 ttcggcattg ttacagctaa cccaagggtt gagttctggt gtattaagag gtgaggaact
    56461 gaatgctgtg tttgagtcag cacctaacat catccaatcg attgcagatt atttggacgt
    56521 ggacatagga aaaataagag gaatggcatc agagggaatg ttaacagcag atattgtaaa
    56581 aaactcatta cttgcagcag cagagcagac taatgcagag ttcgagaaga tgccttatac
    56641 gctaggtcaa atctttacta gtgtaaaaaa taatgcagtt atggtatttg gagctataca
    56701 gaagaaaatt gaggacacag tttcaagcag gggatttcga actttcataa ctgatgttaa
    56761 agactcatta tatgtacttg gagcagttgg gtttaatgta tttagtggat ttattaattt
    56821 actgagtagt ccagcttttc agaatttttt taatgtgatg attgttggaa ctagtttagt
    56881 tgtacaaggg ctaggttgga taataacaca agcacttagt gttgctaatg tattttcgcg
    56941 aaattggagt ataatttcac ctataatttt aggtgtagtt tcagctatta gtacctatat
    57001 aatagctctt ggtattatgc aagcagttac tatagctgga actgtagcaa attggatgtc
    57061 gtggacatct gaagttatta gacaaagagg aattttagga acagctagag ctttagcgat
    57121 aggcaaagct gaacaatggg gatttaatgc tgctatatat gcatgtccca ttttttggat
    57181 agttttaggt ataattgcag taatatctgc tgtatttata ttagtagcag tttacaatca
    57241 ctttgcaggc acaagtattt ctgcaatcag tcttatagtt ggagcttggt attggttatg
    57301 tgcagttgtt tacaacgtaa ttgtagggat agtaaatgct ataaatatct gtgtggttga
    57361 aatagcaaat atctttagaa ctggattata tgcagtgcaa tgtttcttta ttgatatggc
    57421 taatgcagga ctcaaggcag gtgttaattt agacaaagct tttgataaat ttgctaccaa
    57481 tctagcaaat ggtattataa aagctgttaa tatagctgta aaaggattga attggttagt
    57541 acaacagatt aataaaattc caggaattga tttaccacaa atgaaagaat ttcaaaaagt
    57601 aaatactgta attggtacaa aaacaacatt taaacccatt caaaaaccgc ctgagcctaa
    57661 agcatggaaa ccagaattag tagagtacaa aaatttaaag tcagaattta taaaaggata
    57721 tgacgtagga catcaattac aaaacaaatt taaagatact tttgacatta gcaagatagc
    57781 cgaaaaagca aaaaaagatt taggtctaga tgacctttgg gataaaaaat acggacttgg
    57841 tgatggattg ggttcagctg gattaaattc acctttgagt gacgcagcaa aaggagcaaa
    57901 ggacacagca ggcaatactg caaaaatggc aaagactatg gataaaagtc aagaggactt
    57961 aaaatatctt agagacattg cagagcaaga aacaataaac cgattcacag gggtaaatat
    58021 aaaaattgac atgaacaaca ctaataacat aagtaaagat gcagatgtgg atggtatagt
    58081 taatgtacta acagaaaaac tgaatgatgc tatggttgta tctgctgagg gaatagttta
    58141 gagaggaggt gtaatcgtgg cttatgattt ttatttagat ggagtacaat taccaatacc
    58201 tccaccaaag ttagagatta aagttacaaa taaaaataag acagttgatt tgataaatac
    58261 tggagaagta aacatattaa aaaaagaagg gctatctgaa ataagttttg aagcagagtt
    58321 tacacataat aaattacctt tttatcgtgg aacttttagg gatgttcaat tctttttaag
    58381 taagctagaa ttactaaaaa ctgattgtaa gccatttcaa tttattgtat cgagggaaat
    58441 gggtggaaaa gtactattta acactaatat gaaagtgtca ttagaagaat ataacatagt
    58501 agaagatgca gacaatggtt cagatgttaa agttgcaata aagttaaagc aatatagaga
    58561 ttactcaact aaaaaattag ttcctgcaac tcctgaaaag acaaactatg gtaggactcc
    58621 cactccagtc atgaaaccaa aagaatttag accagattca tccaataagc caaatggtaa
    58681 aacatataca gtaaaagcag gggatagcct ttggtcaatc tgccagaagc aacttggtaa
    58741 tggttcatta tataagaaag tatatgagtt aaataaaaca atgatggata aagctaacaa
    58801 gggtaaaaaa gtacctaaat acacaattta caaagggcag gtgttaaaac ttggctgatg
    58861 aattagttct ggcaaatgat agggatgtaa ggctagttat tgcacattgg gaagatttct
    58921 acgaaccagt tgtccttgat ggtatcacat gggagataga aagaagagga acaccttcta
    58981 agttagaatt tacaatagtt atggatgata tattagagtt ttgcgaagga aattctgtaa
    59041 ggctgtatta taaaggaata ggtatcttct atggatatat atttcagaag aaaagagata
    59101 aagaaaatca cattaaaatt gttgcttacg accagctaag atattttaag aataaagata
    59161 cttatgtata tagtaataaa actgcaagtg aacttgtaaa aatgttggct aaagatttta
    59221 atttaaaata caatgtcata gaagatacta agtataaaat atctaggata gaagaaaata
    59281 aaacactctt tgacatgata ctaacagcac tagatgatac tctaagagag aaaaaggaaa
    59341 tgtatgtttt atatgatgag tttggaagaa taacattaaa gaatgttgca tcaatgaaac
    59401 ttgatacggt tatgaacaat gatgtaattg aggattttga ctataattca tcaatagata
    59461 gtgatactta cacaaagatt aaacttgtca gagacaacga ggagtcagga aaaagagatg
    59521 tgtatattgc acaagattct acacatatga gaagttgggg aatactacaa ctatttgata
    59581 cagtagataa aaacatgagt gaagcagaga taaagcaaaa atgtgatata cttctaaaac
    59641 tatataataa gaaaactaag tcattaagtt taaaaaatgt gttaggagat attagagtaa
    59701 gagcaggttg tttagtacct gtttttttag atttaggaga tattgattta caaaattata
    59761 tgttagttga gaaagtaaag cacacatttg aaaataattc gcactttatg gatttgactc
    59821 ttgttgatgg agatgaattt gcttcttatt cttcaagctc atatagtagt ggaaatacta
    59881 ataataaaga tgaaaagaaa aatggtcctg cacaaagtac tacaagtaaa gaagacaatg
    59941 atatgataaa taaattaaat aaagtattta aaaataagtt atcaaataca ggaagtatat
    60001 ttgttaaata ttctaatgct tacaaagtca atgcagcttt aatggctgct atttctatac
    60061 atgaaactgg taatggaagt tcttcacttt gtaaaaataa aaataatttc tttggaatga
    60121 aaggaatgtc ttttggctct gtggatgaag gaataaaaag aggtataagt aatttatcaa
    60181 gaaactatat ccatatggga agaaaaacat tagaaagtat tagagacaaa tatgctccac
    60241 tttatgatag tcctcttaat aaacattggg taccaggagt aaataagttt tataaacaaa
    60301 taacgggaaa tgcatatagt tctaatagtg caggtacagg tgttagaagc aacgaggaag
    60361 cagaaaagaa tttaaaagat ataacttatc aagttcaaaa tagcaacaat gctaatacat
    60421 caacaaacaa taatagtaaa gtaaataaag ttattcaaga agcaaaaaat caacttggca
    60481 agccttacaa atggggtggt aatggtccaa agagttttga ctgtagtggt cttatggtgt
    60541 gggcattcaa aagaggtgca ggtataaatc tcaaaagagt ttcagcagac caatcaaatg
    60601 atagtagagg aaaactatta tgcaacataa atgatgtaaa agctggcgat ttagtattct
    60661 ttgcatacaa ccaaggaaaa ggaaatgtac atcacgttgg actatgtata ggaaatgaca
    60721 agttcataca ttcaccaaat actggtgatg tagttaaaat aagcagttta agtggtagac
    60781 aaaaacaaaa acatgatttt gcaagagcta gaagattctt ttaagtgagg tgataatatg
    60841 agccaagatt tattacaaat aataaagaaa gctgcaatgg atgcagtaga aacaagcaac
    60901 ccaatgcaga ttgcatttgg aactatagaa agtgttaatc ctttagtagt taagatagag
    60961 caaaaagcct cttttgaaga atcttttcta atacaaacag atacatttaa aagatataca
    61021 gataaaaaga taggagataa attagtctta attaggatgc aaggaggaca gcaatatttg
    61081 attttagata ggatgtgatg aaatgttacc aacagataac attgactatg atatagaaga
    61141 tgtatcgata attaattttg atgtaaggca agaaccaagt aagaccttta aattaaatat
    61201 agaaaaatct aagatagatg gtatttgtga tgatgtggaa gcattaaaac aaaccatctt
    61261 tttaatttta aacacagaga gataccaaca tctaatatat agttggaatt atggagtcga
    61321 gttgaacgac cttattggag agcctatatc ctttgtaatc cccgaacttg aaagacgaat
    61381 caaagaagca ctaattcaag atgataggat tgaaaatgta gataattttg agtttgaaaa
    61441 tataaaagga aaggtcaatt gtaaatttat ggtccatacc aaatatggaa atatcaaagc
    61501 agagagggtg gtgagtgttt agtgtttgaa tttatgacat ttgaaaatat aattaaaaga
    61561 atgctagata gtgtacctag cacgcttgac aagagagaag gttctataat atataatgct
    61621 cttgctcctg ttgctataga gttatctgaa acttatattg ctatggatga attactagac
    61681 caaacattcg tagatactgc cagttattac tacttggaga aacgatgtaa ggaaagagga
    61741 attacaccac tcgaagcaac taatacaatt gcaaaaggag tttttaacat agatattcca
    61801 cttgattcta ggtttaatct aggagaatat aactatgtag caattgagag aatatctgaa
    61861 tgtatatata agatgaaatg tgagactgcg ggacctattt ttgagttggg gcaactaata
    61921 cctatcgaat atatagacaa attagaaaca gcagaactga cagaaatact gataaatgga
    61981 gaagatgaag aatcagagga cagtctaagg caacgatatt atgatagttt aaattcacaa
    62041 tcatttggtg gaaatatgca aaattataaa gatgaagtta acaaaataca agatgttgga
    62101 ggagttaagg tttatcctgt gtgggacggt ggaggaactg ttaagttagt aataattaat
    62161 tctaatttca aagtaccatc agaggattta gttaatttag tgcaagaaga aattgaccca
    62221 attggacatc aaggacaagg cttaggatta gcaccaattg gacaccgagt cacagttgaa
    62281 ggagttacaa gtacaactat aaatatatca gcagaaataa catataagag tggatataca
    62341 tgggagaata taaaaacaat tgcagaagaa gcagttgatg actatttaaa tgaacttaat
    62401 atgagttggg aagatgaaga aaacttaata gttcgtatat ctcaaattga aactagatta
    62461 cttagtattg atggagtatt agacattgca aatacaatga taaatagcat tgcatctaat
    62521 cttaatgttg ataaagattc tatagtatta agaggtgaag tagttggata aagagattaa
    62581 tctaataaat tacttaccgc aaatcctacg agataaagaa gaatatataa aagtatttaa
    62641 tgtagaaaac aaagaaataa aaacactaca tgaaaaatta aatgacctat caaatgacca
    62701 gtttttagag gatttaactc caagtggcat aaaaagatgg gaaaagataa tgtctataac
    62761 tcctaaaagt aatgagagtt tagaagatag aaggtttagg atttttagta aatatataag
    62821 taaattacct tactcagaga gatttttaag gaactggcta gataatgtag ttggagaagg
    62881 caattatgag ttaactataa ataatgctac ttataatata catcttgaaa gtgatgctag
    62941 aaatcaagat tggtttgagg aagttcattc ttttgtaagt aatattaagc catgtaatat
    63001 gactttagat tacactagag tgcttataag caaagacaat tatatgaatt ttggtataac
    63061 aaccctaatg ggtcaagaaa taactatata cccttggagt ccaccagata tagaaactta
    63121 tggagaaatt gatgtattaa ctggcaatgg agttggatac caagagataa caatatttta
    63181 ggaggtgata tattggctat agataaaagt tattacacta taattacaga tgtaggaaaa
    63241 gcaaagatag caaatgcaag tgtcacaggt aataaagtgg gatttgtaaa aattcaactt
    63301 ggtgatggag gagggagtga atatactcca actgagagtc agacagctct caaaaacgtg
    63361 gtatgggaag gcaatattgg aaatacaact acagatgaaa ctgcaccaaa ttgtataata
    63421 ttagagagtt taataccatc aagtgtaggc ggatttatga taagagaaat aggatattta
    63481 gatgatgaaa ataatttaat tgccatttct aaatacaaag agtgttataa accttctata
    63541 gaacaaggtg cagtggtaga catgaaggtt aaaactgtgc ttattgtatc taatgtaaat
    63601 aatatagaac ttaaaattga cccaacaata atctttgcaa cactcaaaga tatacaagac
    63661 ttagaaacta aaataggtac tgttaatact aaaattgata caactaaaac agagttaaat
    63721 actagaattg acacagaaaa tgagaaacaa aatattaaaa ttgaccaatt aatcgcaggt
    63781 ggttcaaatg tatctcatac gcatattata gagattgatg attggatttt aaataatgaa
    63841 actaatatgt atgaagtaac tataaatcat ccactattga ctaaaagaat actaatagct
    63901 ttatatgatg aaattggtga agcacttaca ccaaacgcta gggctattga tgataatagt
    63961 attcttgtta gaaatgaaga aaatattaaa atgtatgtat atttgataaa tggaaatgca
    64021 gaaactcatt ttataaatgc aactgtggat gataacagag tgtctgaaat gactacttat
    64081 tcgtctaaga aaatcgagga tagattgatt aatatagaag aaaaagtaaa tggtggttta
    64141 tctagtattg caacaagtgt aaatgagttg ataacttatt gttagagagg agagtgagaa
    64201 aatgcagaca gaatggaact ttgggtacaa tggttcgcca caaagtgtta tattgaaacc
    64261 tggcaaatat aaatttgaat gctggggttc ttctggaggt atcaacaatt cttcttggca
    64321 tactgatgct aaaggcggat attctaaagg tgaaattaca ttaaaaaaac aaactacatt
    64381 atatgtttac gtcggcgaaa gtggttttgc ttcttcatct acgagtaata acactaaaag
    64441 tggttttaat ggcggtggta aaggttattt aaatcaacag gttatgggta cttattattc
    64501 tatgtacggt ggtggtgcta ccgatataag acttgttggt ggtgcttggg at
//
LOCUS       DAYAOO010000012        62575 bp    DNA     linear   BCT 12-OCT-2024
DEFINITION  TPA_asm: Clostridioides difficile isolate ST8-SSI-h139-18
            SAMN40601845-rid21577343.denovo.012, whole genome shotgun sequence.
ACCESSION   DAYAOO010000012 DAYAOO010000000
VERSION     DAYAOO010000012.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN40601845
            Sequence Read Archive: SRR28438827
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 62575)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 62575)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-MAY-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-MAY-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002157583.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002157583.1
            Genome Coverage       :: 163x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/11/2024 16:19:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 4,038
            CDSs (total)                      :: 3,963
            Genes (coding)                    :: 3,930
            CDSs (with protein)               :: 3,930
            Genes (RNA)                       :: 75
            rRNAs                             :: 6, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 60
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 33
            CDSs (without protein)            :: 33
            Pseudo Genes (ambiguous residues) :: 0 of 33
            Pseudo Genes (frameshifted)       :: 7 of 33
            Pseudo Genes (incomplete)         :: 25 of 33
            Pseudo Genes (internal stop)      :: 11 of 33
            Pseudo Genes (multiple problems)  :: 8 of 33
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..62575
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN40601845-rid21577343.denovo.012"
                     /isolate="ST8-SSI-h139-18"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Denmark"
                     /collection_date="2018"
                     /collected_by="Statens Serum Institute"
     gene            <1..440
                     /locus_tag="ACGI5H_000876"
     CDS             <1..440
                     /locus_tag="ACGI5H_000876"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417031.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="lysylphosphatidylglycerol synthase
                     domain-containing protein"
                     /protein_id="HFG9696600.1"
                     /translation="NKIESIESFIDDYSKAINFFAKNKKVLISTIIVTFIQLSAYFSV
                     SFWIYKAFNLQGYSYIYILTLQAFLYMAISPIPTPGNVGANELAFFTIFKSVFPQPLM
                     GYAVFLYGGFMYYLILIGSGIFTVITHYRMKNRIGRNIVLSEN"
     gene            691..2835
                     /locus_tag="ACGI5H_000877"
     CDS             691..2835
                     /locus_tag="ACGI5H_000877"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861905.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_except=(pos:1105..1107,aa:Sec)
                     /transl_table=11
                     /product="formate dehydrogenase H subunit alpha,
                     selenocysteine-containing"
                     /protein_id="HFG9696601.1"
                     /translation="MEKKILTVCPYCGAGCQLYLVVKDNKILRAEPANGRTNQESLCL
                     KGRYGWDFLNDPKILTPRLKKPMIRKQGVLEEVEWDEAINYTASRLNEIKEKYGPDSI
                     MGTGSARGPGNEANYIMQKFMRATIGTNNVDHCARVUHAPSVAGLAYSLGSGAMSNSI
                     PEIENADVLFIFGYNGADSHPIVANRIVKAKKNGAKLIVTDPRVTESARIADIHLPIK
                     GGTNMVLVNAFGNVLIEEGLYNKEFVQNHTQGFDEYKEIVKPYTAKYAEKITGIPEEL
                     IRKAMREYAKGKKAMILYGMGVCQFGQAVDVVKGLASIALLTGNFGRESVGIGPVRGQ
                     NNVQGACDMGALPNVYPGYQNVTDDKIREKFEKAWGVKLSPNNGYSLTQVPNLVLKEK
                     KLKAYYIFGEDPVQSDPDASEVREALDELEFVIVQDIFMNKTALHADVILPATSWGEH
                     EGVYTCADRGFQLMRKAIEPQGDVKPDWQIISEISTAMGYPMNYKNTKEIWDELRQLC
                     PSFLGATYEKIETQGCVQWPCKSESMEDKGTMYLYEGQKFSTPNGKGNLFAAEWRPPM
                     EVEDDEYPFSLCTVREVGHYSVRTMTGNCRTLSSLEDEPGRVQINSNDAEKLGIEDDE
                     LVRISSRRGSVITRATVTDRVKEGATYMTYQWWVGACNELTIANLDPISKTPEYKYCA
                     VKLEKLEDQELAEKCVREEYQSLKDKMTATNI"
     gene            2884..3717
                     /gene="fdhD"
                     /locus_tag="ACGI5H_000878"
     CDS             2884..3717
                     /gene="fdhD"
                     /locus_tag="ACGI5H_000878"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417034.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009326 - formate dehydrogenase complex
                     [Evidence IEA];
                     GO_function: GO:0016783 - sulfurtransferase activity
                     [Evidence IEA];
                     GO_process: GO:0009061 - anaerobic respiration [Evidence
                     IEA];
                     GO_process: GO:0015942 - formate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="formate dehydrogenase accessory
                     sulfurtransferase FdhD"
                     /protein_id="HFG9696602.1"
                     /translation="MNNIYSKTKLQENSKDKVFENSYSLVDYKYLNSFNVEVSKINEH
                     EVSIDNEEIIAEYPLSFILNDKYVNTFLCTPYNLEELIVGFLKTKGYIENKKSLLKFE
                     INESERFAKVTIQEKQKNQDEQIIFLNSLDYITCAPVKSNIKINYDTIYSIMDKNLNS
                     SELFKNTGGVHSVSVFNFDKKIVTCEDVARHNAMDKAIGFCVLNDITLKDKIVAVSGR
                     ISLEMILKAAMTQIPIVVSKSAPTNLSIELSKKLNITLIGFVRGRRMNIYANPQRVIK
                     K"
     gene            3728..3901
                     /locus_tag="ACGI5H_000879"
     CDS             3728..3901
                     /locus_tag="ACGI5H_000879"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891795.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9696603.1"
                     /translation="MCTKKEEQRYSKCEICGVLIDDTDKVYNNTYNLCKKCKRNISTE
                     KIVKYINIYDESK"
     gene            3959..4510
                     /locus_tag="ACGI5H_000880"
     CDS             3959..4510
                     /locus_tag="ACGI5H_000880"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003432405.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_function: GO:0051539 - 4 iron, 4 sulfur cluster binding
                     [Evidence IEA];
                     GO_process: GO:0009061 - anaerobic respiration [Evidence
                     IEA];
                     GO_process: GO:0019645 - anaerobic electron transport
                     chain [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="4Fe-4S dicluster domain-containing protein"
                     /protein_id="HFG9696604.1"
                     /translation="MKNKIGSFVIADPNKCTGCRACEVACFTMHNQHNNVGYTVGTVD
                     IPVIPRLYLVKGDNFCMPIQCRHCEDAPCLNSCPQKAIVKENNIMSVNEEKCIGCKTC
                     LLACPFGAIDLLPQYEDGKEVEQVILDENKKIAYKCDLCKDNEKIACISACPQEALKL
                     VTPIDDKKAKNRQAALSLLLTNK"
     gene            4535..5911
                     /locus_tag="ACGI5H_000881"
     CDS             4535..5911
                     /locus_tag="ACGI5H_000881"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429061.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005506 - iron ion binding [Evidence IEA];
                     GO_function: GO:0009055 - electron transfer activity
                     [Evidence IEA];
                     GO_function: GO:0016695 - oxidoreductase activity, acting
                     on hydrogen as donor [Evidence IEA];
                     GO_function: GO:0051539 - 4 iron, 4 sulfur cluster binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="[FeFe] hydrogenase, group A"
                     /protein_id="HFG9696605.1"
                     /translation="MIINIDKDLCTGCRECSKVCPVNAIEGEEGKPQEINLDRCVMCG
                     QCVQTCKSYASVIDEGFEFLQEKKQEREIPESINEPIFAAYNVCDIDKVKKALSDPNV
                     FTMVQCAPAVRVALGEDFGYYLGYLGAGKMAAALRALNFDRVYDTNFAADLTIMEEGS
                     ELIKRVTEGGTLPMFTSCCPAWVKFMEKNYPKLTNHLSSCKSPQQMGGAIFKTYGAEI
                     NNVDASKIFSVSIMPCTCKKYECDREEMDSSGYRDVDVVLTTRELAYLIKDMGIDFKN
                     LREEKFDSPLGSYSGAGTIFGVTGGVMEAAIRTGYELITGESIPDVEVKQVRGENGFR
                     KSTIKIGDLDLRVGVVSGLKNVIPVLEDLEKGKLDVDFIEVMTCPVGCVSGGGQPKIL
                     LEEYKELAYENRTKATYVHDEHLAIRKSHENPDIKKLYDEYLVEPLGEKSHHLLHTTY
                     CIGKEVAK"
     gene            5911..6426
                     /locus_tag="ACGI5H_000882"
     CDS             5911..6426
                     /locus_tag="ACGI5H_000882"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861901.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_function: GO:0051539 - 4 iron, 4 sulfur cluster binding
                     [Evidence IEA];
                     GO_process: GO:0009061 - anaerobic respiration [Evidence
                     IEA];
                     GO_process: GO:0019645 - anaerobic electron transport
                     chain [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="4Fe-4S dicluster domain-containing protein"
                     /protein_id="HFG9696606.1"
                     /translation="MNYFVIADPDKCIGCRTCMIGCVVAHSDEDIFYQNPDEINFNPK
                     LSVIKTKEVSAPIQCRHCEDAPCAKACPNGGIVRVGNTIKINEENCIGCKTCMLACPI
                     GAIDIVTLKDVDEGKLCFRERMTANKCDFCIESPEGPACVNVCPTKAFTIVKDEDIDS
                     KVKNKRKLAIL"
     gene            complement(6504..7787)
                     /locus_tag="ACGI5H_000883"
     CDS             complement(6504..7787)
                     /locus_tag="ACGI5H_000883"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427927.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugated bile salt MFS transporter"
                     /protein_id="HFG9696607.1"
                     /translation="MNTLLNNKFSIKNFSNAWVIVLGCMLIQAVPFSIVASIQPQFIS
                     YVVEGEGFSLASFSLIFTIGTIASAIASPFIGVLFSKVNIKILYLLGCIISSIAFATF
                     SICTELWQFYTVSCIVQIGATIISAIGIPVLISAWFDEESKGKALGFAFAGGSIGSIF
                     LQPLAVRLLATQGYSRSYLIFGIIALIVGIPVILFILRMPKDINEKVKSKGKKEKASD
                     TISPSVWGYTLKEAKKIKYFWIMTIGFIFVGIYVSSLSVQYPTYLRNYLNPILIGTVG
                     STFALFALIGNLFGGLLFDKFGQTKPLIISFVLVLIATLSLLLVDKSSTFAFVFAILK
                     GLSVFAYMIGPAYLTGSFFGQKEFGSIYGIVQLIFAVGFALGSTLFGLLVDNFGYRFS
                     WSIIILSVIIAYTLLIITSIGMKKLNKERLDKLMQ"
     gene            7975..8397
                     /locus_tag="ACGI5H_000884"
     CDS             7975..8397
                     /locus_tag="ACGI5H_000884"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018112711.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3783 domain-containing protein"
                     /protein_id="HFG9696608.1"
                     /translation="MSFEKINNNNLDKIHNRKCIMLVNFNKKELSLIKNVSNFAGIRD
                     HIILSDKNGENIIRDILDGNISNECENGIKSKSVIFNNTPSTQVNAFLEGLKKVRINR
                     PFTAMVTETSIDWTLNNLIENLVQERNAMSLGKTIEHK"
     gene            8499..9437
                     /locus_tag="ACGI5H_000885"
     CDS             8499..9437
                     /locus_tag="ACGI5H_000885"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891785.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoglycerate dehydrogenase"
                     /protein_id="HFG9696609.1"
                     /translation="MKVLFTINYGKEKFDKIRELGYDVIHYSEDSIENNEDVNTADVL
                     VTYNPFERLDISKMKNLQYIQTTSVGIDQLPKEEVLKRNIKIANNRGGYSVPIGESIV
                     LYILEIYKNSAKFFKQQQNKEWKMDFSVSELYGQRVGFLGTGTISSEAAKRLKAFGVE
                     IWGVNTDGSSKKYFDKCFATEDMNIVFEECDIVVVAMPSTKSTDGIVNKDMFKLMKDG
                     SVFINVGRGNTVNQKDLEECVEKFRGVALDVFESEPLNKDNKLWECENVIVTPHNSWV
                     SDKNKERTFNMVYNNLKHYIMENKPVDNVVDISRGY"
     gene            9623..11647
                     /gene="ligA"
                     /locus_tag="ACGI5H_000886"
     CDS             9623..11647
                     /gene="ligA"
                     /locus_tag="ACGI5H_000886"
                     /EC_number="6.5.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861898.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003911 - DNA ligase (NAD+) activity
                     [Evidence IEA];
                     GO_process: GO:0006260 - DNA replication [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NAD-dependent DNA ligase LigA"
                     /protein_id="HFG9696610.1"
                     /translation="MSVKDEINKLIETINYHNERYYNQDSPEISDYEYDKLMKELISL
                     EEEHPELKRIDSPTNRVGGKPLDKFNQIVHKTPMLSLSNAFSEQDLRDFDKRVQEYVG
                     ENVEYVVEFKIDGLSVGLTYNNGEFEKGATRGDGVVGEDISQNLMTVKSIPLKINDKK
                     ELIVRGEVYISKDNFRKVNEQQEEQEQPLFANPRNLAAGSLRQLDPKLTAKRPLDIFV
                     FNMENIEEYDLESHSESLEYLEKLGFSVSQSYKVCKSIDEVIEHIEYWTDNRGNLDYE
                     IDGMVIKVNNIKQRDEMGYTAKSPRWAIAYKFPAEKKKTKIVDIIVEVGRTGTITPSA
                     ILEPVRLAGTTVSRATLHNEDYIREKDIKINDTVLVQKAGDIIPQVLEVIKEERTGDE
                     IDFKMPEKCPVCSEPTIRLEGEAAVKCINMSCPAQIRRGIIHFVSRDAMNIDGLGESI
                     ITLLLNEKIIQDVSDLYYIKKEDVVDLERMGEKSADNLINSIEKSKENDLWRLINGLG
                     IKFIGVKAAKILAYNFKDLDEVISATSEQLEELEEFGSIMANSVVEFFKEDKNMNVIN
                     KLKNVGVNTKSLDNTGEKVEKIFEGMKIVLTGTLPTLKRNDAKDMIEKRGGKATSSVS
                     KSTTFVLAGEEAGSKLTKANDLGIKVIDEERFLELLKLSSKDEVKAVLES"
     gene            11807..13156
                     /gene="rph"
                     /locus_tag="ACGI5H_000887"
     CDS             11807..13156
                     /gene="rph"
                     /locus_tag="ACGI5H_000887"
                     /EC_number="2.7.7.56"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000049 - tRNA binding [Evidence IEA];
                     GO_function: GO:0009022 - tRNA nucleotidyltransferase
                     activity [Evidence IEA];
                     GO_process: GO:0008033 - tRNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease PH"
                     /protein_id="HFG9696611.1"
                     /translation="MTRSYDRSNEQIRPVKITRDYTKYAEGSVLIEMGETKVICTASV
                     EEKVPPFLRNSGTGWINAEYSMLPRATQQRKIRDASRGKIDGRTQEIQRLIGRTIRSV
                     VDLNKLGERTIWVDCDVIQADGGTRTASITGAFVAVAEAIYKLYKAKTIKEMPITNFV
                     SAISVGIVNGIHMLDLCYEEDSKAQVDMNIIMTDKCEFVEVQGTGEEKPFSRADLNLL
                     LELGEKGNKELIRLQREALGEISDEILGMDYGNEVVIATNNAHKLEEIGEILKDFEYK
                     VYSLKDVDLAGIEIVEDGKTFEHNALIKARTIAKKTKLIAISDDSGLEVDALGKKPGV
                     YSARYAGEHATDEENRKKLLKAMQNVPMSKRNARFVSAIAVVFPDGKEFVVRGICEGM
                     IGFEEKGKNGFGYDSLFIVKGYDKTFGEIPSVIKNSISHRANALKLMKQEFIKRVVK"
     gene            13156..13626
                     /locus_tag="ACGI5H_000888"
     CDS             13156..13626
                     /locus_tag="ACGI5H_000888"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427939.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metallophosphoesterase"
                     /protein_id="HFG9696612.1"
                     /translation="MKIGIVSDTHMMIKNMEKTIPYLKECDLIIHAGDNFTDSRYIHS
                     MTNVGIIAVKGNCDFDAVEEEVVFEVANKTIFLCHGDKYGVKYGTNMLEKKATEVDAD
                     IVIFGHTHTPFREIKDGVLYINPGSTSLPRGVSYKSFVIMDIEEDDIKIEEIRI"
     gene            13820..15106
                     /gene="tig"
                     /locus_tag="ACGI5H_000889"
     CDS             13820..15106
                     /gene="tig"
                     /locus_tag="ACGI5H_000889"
                     /EC_number="5.2.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417090.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005854 - nascent polypeptide-associated
                     complex [Evidence IEA];
                     GO_function: GO:0003755 - peptidyl-prolyl cis-trans
                     isomerase activity [Evidence IEA];
                     GO_function: GO:0051082 - unfolded protein binding
                     [Evidence IEA];
                     GO_process: GO:0015031 - protein transport [Evidence IEA];
                     GO_process: GO:0051083 - 'de novo' cotranslational protein
                     folding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="trigger factor"
                     /protein_id="HFG9696613.1"
                     /translation="MKAELIKKEGNKVTLKITVDNNKFEAAVNKAYNKSRNKYNIPGF
                     RKGKAPRIVIETQYGKGIFYNDAIEILFPEVYPEAIKELDIDPIDNPDLDIEEISKDN
                     GLVMVLNVEVKPEFELGNYKGIEIAKVENTVSDENVDAKLQEMVEKNARLVSVEDKAL
                     EDGDTAIIDFEGFENGVAFDGGKGENYNLVIGSNTFIPGFEEQLVGKKAGEEVEVNVT
                     FPEEYHSQDLAGKPVVFNVKINDVKVKELSALDDEFAKDTSEFDSLDELKADVRAKLE
                     EEAKNRADAETRNSVVEKVAENTEIEIPEVMIQHQIDNMLNELNYQLQYQGFGLQQLL
                     EMTGRTMEELREERKEDAKKLVKSSLVLEAITKAEGIEATEEEFKAELEKMASAYNME
                     VEKIEASLRDADKEDIKGQIKIRKTIDLLVDNATIA"
     gene            15256..15840
                     /gene="clpP"
                     /locus_tag="ACGI5H_000890"
     CDS             15256..15840
                     /gene="clpP"
                     /locus_tag="ACGI5H_000890"
                     /EC_number="3.4.21.92"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417102.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009368 - endopeptidase Clp complex
                     [Evidence IEA];
                     GO_function: GO:0004176 - ATP-dependent peptidase activity
                     [Evidence IEA];
                     GO_function: GO:0004252 - serine-type endopeptidase
                     activity [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp endopeptidase proteolytic
                     subunit ClpP"
                     /protein_id="HFG9696614.1"
                     /translation="MALVPVVVEQTGRGERSYDIFSRLLKDRIIFLGDQVNDATAGLI
                     VAQLLFLEAEDPDKDIHLYINSPGGSITSGMAIYDTMQYIKPDVSTICIGMAASMGAF
                     LLAAGAKGKRLALPNSEIMIHQPLGGAQGQATDIEIHAKRILKIKETLNEILSERTGQ
                     PLEKIKMDTERDNFMSALEAKEYGLIDEVFTKRP"
     gene            15859..17109
                     /gene="clpX"
                     /locus_tag="ACGI5H_000891"
     CDS             15859..17109
                     /gene="clpX"
                     /locus_tag="ACGI5H_000891"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417105.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0046983 - protein dimerization activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp protease ATP-binding subunit
                     ClpX"
                     /protein_id="HFG9696615.1"
                     /translation="MSKYEEKRQLKCSFCGKNQDQVRRLIAGPNVYICDECVELCDEI
                     IQEEIEDTIDEDTTSLPKPKEMMEILNDYVIGQEKAKKALSVAVYNHYKRIYSKKSSS
                     KDIEIQKSNILLLGPTGSGKTLLAQTLARTLNVPFAMADATSLTEAGYVGEDVENILL
                     KLIQAADFDIEKAERGIIYIDEIDKIARKSENPSITRDVSGEGVQQALLKILEGTVAN
                     VPPQGGRKHPHQEFLKIDTTNVLFILGGAFDGLEKIIQKRGGDKTLGFGAKIESKKEL
                     DLGKLYEKVLPEDLLKYGIIPEFIGRIPVLATLELLDEDALMQILQEPKNALVKQYKK
                     LLELDDVELEFEEGALRAIAKKAIERNTGARGLRSIVESVMMETMFEVPSRDNIKKVI
                     VTEKSVNEDSVNPIIVLKDQEESA"
     gene            complement(17180..17707)
                     /locus_tag="ACGI5H_000892"
     CDS             complement(17180..17707)
                     /locus_tag="ACGI5H_000892"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427941.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chromate transporter"
                     /protein_id="HFG9696616.1"
                     /translation="MSEIILLFLIFLKIGAFSFGGGYAMLPFIQQEFISKYHFITNQE
                     FLDLLAISQSTPGPVAINSATFVGFKTAGFFGSLAATIGVTIFALIGLTIISKLFSKF
                     KNNKKVENLLTVLRPITLGFILSAAFSSAKEVNWDLYGIIAFIASFYLLYKGKIGSIA
                     IVFVFGILGILLTFL"
     gene            complement(17695..18207)
                     /locus_tag="ACGI5H_000893"
     CDS             complement(17695..18207)
                     /locus_tag="ACGI5H_000893"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417110.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chromate transporter"
                     /protein_id="HFG9696617.1"
                     /translation="MLKLFLTFLKIGAFTFGGGYAMVPLIQDELVNKQKLLEQEEFID
                     YLSIAQSYPGVLAVNISVLLGYKLYGIPGVLICTLGSALPSFCIVLVLSYLYFKNSSS
                     KILDGFFKGVAPVVIALILYSFTSMFKKLPKSKTNILLLIIAVLSVGVFNISPIYLII
                     GGGVYSLCQK"
     gene            18387..20750
                     /gene="lon"
                     /locus_tag="ACGI5H_000894"
     CDS             18387..20750
                     /gene="lon"
                     /locus_tag="ACGI5H_000894"
                     /EC_number="3.4.21.53"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903709.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004252 - serine-type endopeptidase
                     activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="endopeptidase La"
                     /protein_id="HFG9696618.1"
                     /translation="MEQNYTKIDHELPLIPLRGLAIFPYMILNFDIGREISLKALDQA
                     MMDEELIFLTSQKEAEVDEPGEEDFYHVGTICKVKQMIKLPGDTVRVLVEGVSRGRVK
                     KIEQEDGYFRAVIEEIVFDSDNLDSETEVEIEAFVRNVFDAFEEYINIGNRVSPEILI
                     SLADIEDVDRFIDTIAANIYLKSSQKQEILEEFDIRKRLELIYSILLEEIDILKIEKK
                     ITLRVKKQMNKVQKEYYLREQLKAIQKELGEEEDINSEADEYREKLKKIKAPKTTKEK
                     IEKEIDKFSKISSMSPDVSVSRNYLDTIFSLPWNKETKDKLDITKAKDILDEDHYGLE
                     KVKERILEYLAIRTLAKSLKGPIICLVGPPGTGKTSIVKSIARALNRKFVRISLGGVR
                     DEAEIRGHRRTYVGSIPGRIINGVKEAQTKNPVFLFDEIDKMAADYKGDPASAMLEVL
                     DPEQNKDFVDHYLEIPFDLSKILFVTTANSLSNIPRPLLDRMEVIEVSGYIEEEKLNI
                     AKKYLLPKQIKEHALKENFIKIDDETLRSIINHYTREAGVRTLERTIGKICRKVAKKY
                     VEDPTLEEVVINKSDLETYLGKDMFKYQLAEVNPQIGLVNGLAWTEVGGVTLEVEVNV
                     LKGKGEIVLTGKLGDVMKESAKTGISYIRSIVDKFDIDPEFYKTNDIHIHIPEGAVPK
                     DGPSAGITMALAVISALTKRPVPGNIAMTGEITLRGRVLAVGGVKEKLLAAHRAGITK
                     VLIPKECEADLDEIPENVKEKMEFVLVEHMDEVLEQALLKSGENNEN"
     gene            20740..21351
                     /gene="yihA"
                     /locus_tag="ACGI5H_000895"
     CDS             20740..21351
                     /gene="yihA"
                     /locus_tag="ACGI5H_000895"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891775.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0003924 - GTPase activity [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_function: GO:0043022 - ribosome binding [Evidence IEA];
                     GO_process: GO:0042254 - ribosome biogenesis [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome biogenesis GTP-binding protein
                     YihA/YsxC"
                     /protein_id="HFG9696619.1"
                     /translation="MKIRSSEITMSAVNKSQYPAEGIPEIALAGRSNVGKSSIINTLL
                     NRRNFARTSQTPGKTRTINFYLINNEFYFVDLPGYGYAKIAKSEKEKWGGIMERYLES
                     RQELCSIFLLVDIRHEPTADDKLMYEWIKHFGYNCVVIATKADKISRGQYQKHISIIR
                     KKLQMESSEKVIPVSSLKKTGVEELWEEIVNQYNQHGYEITVD"
     gene            complement(21616..22986)
                     /locus_tag="ACGI5H_000896"
     CDS             complement(21616..22986)
                     /locus_tag="ACGI5H_000896"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435615.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HFG9696620.1"
                     /translation="MKQKWIVLIIICIGVFMSTLDGSILNIANPTIAADFKINMSQIQ
                     WVVTAYMLVVTATMLFFGKLGDKVGSNRLYTLGFFIFTIGSFLCSMSNNLSTLISSRI
                     FQAVGASILMATGLGIVSNAFPANEKGKAIGITGAVVGIGNMSGPVIGGIILEHFGWP
                     SIFIINIPIGIIAVFLGIKFLPKPVLDEQNKSFDIPGLLLFASCTTLILLAMNEKGNT
                     RLYLGITALIIFLLLALREVKFEQSFIDLPLFKNRNFTVGNIIGVACYFPQMAVSFLL
                     PFYLEQLKNLSPMMAGYVMTVHPLIMVLIAPIAGSLSDKHGAKNILTASFSFMTISLV
                     GMALLKADSPLYLLIVCLVIFGLGLGAFSSPNNSSILADVPPQKQGYGGSFLATIRNL
                     SFALGTAFFSSFFAQSLTYNQKFKSHTSAYVIASNQSYWIAASVCFIGLILTVFFMRK
                     TDKSIS"
     regulatory      complement(23161..23276)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00050"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="FMN riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="flavin mononucleotide"
                     /db_xref="RFAM:RF00050"
     gene            23564..24643
                     /locus_tag="ACGI5H_000897"
     CDS             23564..24643
                     /locus_tag="ACGI5H_000897"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891772.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HFG9696621.1"
                     /translation="MEGKVKKAFPGGNTSQGSYSFFDYIIPENVKRVFCLKGGPGVGK
                     SSLMKKIYKEFLHRGYDIDLYHCPSDPSSLDGLVIKKLGVVLMDATAPHTMDPKLPGA
                     LDEIINLGDYWNTEELEKNKQEISVYDKDISNSFKRAFKFLKSAEPIFRDIEEKYSDC
                     MDYGKVNLVTEEFIKRLFDGVKSTGNLKREKHLFGSAITPVGCLDYTENILKDVKKVY
                     YLDGEIGTGKTTLLNKVYKKAIEKGLNVEVYHYPLIPEKIETVLLTDLDIGITISTTF
                     KEEDTIDLNQFLNREKLLKYEEDIKFDEKVLDDLICWAVLNLKRAKSKHDIIESYYSP
                     NMRFDEVGKLRDKLIKRILKYEENL"
     gene            25034..25714
                     /locus_tag="ACGI5H_000898"
     CDS             25034..25714
                     /locus_tag="ACGI5H_000898"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417129.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF881 domain-containing protein"
                     /protein_id="HFG9696622.1"
                     /translation="MKKQYVFIILASTILGILVGTIFRDYSNEETVYTSKDKSIRKEI
                     KMTRKSIKELTKEKDKLDKEINSMKQNQKNSEEISEIETLRDSLSYSDVKGSGIILSI
                     DAIDEKTGNIANSIDYNKILVKVINELKVNGGKYIEINGQRINQYSEVVLAGSHININ
                     GVPVAQPYEIKCIGDKEKLSNYVDKGSKYLDSIQTNYPMKISIKTEENISMKKMNIPN
                     KLKYIKGD"
     gene            25707..27086
                     /locus_tag="ACGI5H_000899"
     CDS             25707..27086
                     /locus_tag="ACGI5H_000899"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435622.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0009306 - protein secretion [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GspE/PulE family protein"
                     /protein_id="HFG9696623.1"
                     /translation="MIKIILEESSLPMLIPEKLAKKYNVFPVEFQDDNLVVEIEDEDI
                     YALQDLRLATGKEIILKKEKKELISEKIEKYYNSFELDEDYAKKLFENLLEKAIKENA
                     SDIHIEPFKEHLIVRMRVDGELKEVSKFLVDVYPSLSTVIKLKASMDITEKRLPQDGR
                     VDIKLGGNLIDIRVSSIPTVYGEKIVLRILNRDTFLKDKLELGFSEEAIKSINRIINK
                     RAGILLVTGPTGSGKTTTVYSLLNDLKGINKNIMTIENPVEYKMDGISQIQVNSKVGL
                     SFDVGLRAILRQDPDIIMVGEIRDAETAKIAVRAAITGHLVISTLHTNDAVSSIARLL
                     EMQIPPYLLNASLIGVISQKLVRKVCNHCSHEIMIKDNFSGDVNTKVAVGCEKCNDKG
                     YFGRTAIYEILEINDDIKTCIRNMEDSSTIKDVAQNNGMITFEDSCKRLINEKITTLE
                     ECLVVNEMI"
     gene            27257..28342
                     /locus_tag="ACGI5H_000900"
     CDS             27257..28342
                     /locus_tag="ACGI5H_000900"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898464.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type II secretion system F family protein"
                     /protein_id="HFG9696624.1"
                     /translation="MRLSKNIFYNLEKFYLVLNRISDKEIRVICKEIGILLESGCEIT
                     KIFEIIESQSSKKVKNLLSIVSNHIQKGNSIAESFQITGIFSKFFISMIKAGETSGNL
                     DIIMSDLSNYYDKEYKLKMKIITISIYPIILIILSILSMLFIFVFVIPNFQVVFTNNG
                     IEPPLITRVLMGISTVVTNNLAYIIFSFILFSIGSIYFFITNDNIKKLINSLKFKIPF
                     IKKINQLVATTRFSRALSVLISSGIQIVEAIDMSASVIDNEFIYERLKISNNYIKKGN
                     SIGKSLNLANIFPKLFISMANTGEESGKLDKSLNVINKFYENELNNKIEQIMKFIEPM
                     LIVFMGLIIGTFILAMVVPMFDAITNF"
     gene            28396..28755
                     /locus_tag="ACGI5H_000901"
     CDS             28396..28755
                     /locus_tag="ACGI5H_000901"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891768.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type II secretion system protein"
                     /protein_id="HFG9696625.1"
                     /translation="MINLINKKRKGFTLVEMIVVVTILGVISSIALVKYSKVQESAKL
                     NADYTNAANIVTAASMAINDDEKTIDSLSVETLKEKGYLNTVPVPQSTSGKFELVIND
                     SGTDISVNINSKQFYPK"
     gene            28808..29680
                     /locus_tag="ACGI5H_000902"
     CDS             28808..29680
                     /locus_tag="ACGI5H_000902"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435627.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pilus assembly protein PilM"
                     /protein_id="HFG9696626.1"
                     /translation="MAIIKKILNLEINDDYIRLVFLRKSHKKVFIDKSIIKEINFDIK
                     NDSNSIEKIKYIEDVVRFVKEEIGKSKILYKNLYFNIQIQDIVIRNVEVLNTKKKRDI
                     LSMIEFEITQYIPININNYSIKYKVINSKNDKLNIQVILFPKNIIQLIKNISENLNMN
                     PKTININFDILQKLINLNLIENFSEEGVFIECKKSQLIINITKDKKIRETYLLSKEGK
                     SYEFIKRLLRGFKYVYYYGIENCFIEEYFKYTDKSIEVNPLRLKDKVKVENNFDADLE
                     DNRINYINSIGMII"
     gene            29681..30124
                     /locus_tag="ACGI5H_000903"
     CDS             29681..30124
                     /locus_tag="ACGI5H_000903"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728431.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9696627.1"
                     /translation="MKVDKTINFLNGFKKTKPCNKIYKIIIVLILTCILFKSFMYVKS
                     INELEDYISQNKLVDKSKNTLPTTDKTREKFSKIKLNEIKKIYETIGINSITKISIDK
                     NKLEMEGVCSDLDVLNNLRKIKYIKYYYIDSIVRDGEYYRFRIKS"
     gene            30139..30723
                     /locus_tag="ACGI5H_000904"
     CDS             30139..30723
                     /locus_tag="ACGI5H_000904"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9696628.1"
                     /translation="MRLNNREKNLLKILLILVIILASDIAVSYLEENLTSLKNEKQNI
                     INKINNQDNYQIKDNKHIDDKYIESVELNKNEELKNNFNNSFLDKKTNKDIVLLVENE
                     LRDIVNVEYINQESSLDNHNKKQVNLEIKVNGELANVLKLEGVMKKLRLNNKLEKIEI
                     NKLKVNNFDVQNIPNEYKQEKDNIVECKMTVRVI"
     gene            30976..32013
                     /locus_tag="ACGI5H_000905"
     CDS             30976..32013
                     /locus_tag="ACGI5H_000905"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009906384.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="SEC-C metal-binding domain-containing protein"
                     /protein_id="HFG9696629.1"
                     /translation="MLGRNELCPCGSGKKYKKCCLNKDIVSERACRKTELSQKQYTDL
                     YSKLYDYSRQDKFKEECEKAKEMFYIMQNDSVNEKFERFFNTYLIQDHIMENKKVMTV
                     GFLEENGANLSQSEVSILKSMFESYVSIYEVKEVSAGKIVLKDCLNGNELCTEDVKLL
                     RSFKIGSCMIARIVDIEGTNILIDITISISNEVKDIILKDIMNLFNQYQDVYKDMKSF
                     LIYHTHILYKYIQQLLDPSIAEYLKRERDKNDTKVNSENELAEEECKVLDTLKENVEK
                     ENIDACIEFWNEYKKNHENIKGAENGWAAAVEYYVKKEAGQPITQVQISKKYDISSST
                     LGKRYKDLKIS"
     gene            32094..32459
                     /locus_tag="ACGI5H_000906"
     CDS             32094..32459
                     /locus_tag="ACGI5H_000906"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417144.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9696630.1"
                     /translation="MSLSLGNAIAVSTNFIKSNPAVPVYNGEEIYAVIYHIEIGYNNG
                     VSPDTKQYIIIDYKEFDLSMDKKNELINIAKEYCKSKGIVENENLEINLLDNEEAENF
                     LEKVFNNMKVIRGLITKKG"
     gene            32464..32781
                     /locus_tag="ACGI5H_000907"
     CDS             32464..32781
                     /locus_tag="ACGI5H_000907"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435631.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9696631.1"
                     /translation="MDYIGIENITPYENTYEFSVYEYDDEITLGSEKLYVCELRVVLI
                     KVNSLYVERLHKSVEAMVLVKNLKKDLDKTLVVNKIKNFVLDEIWVENLVKENIEVIF
                     VES"
     gene            32829..34433
                     /locus_tag="ACGI5H_000908"
     CDS             32829..34433
                     /locus_tag="ACGI5H_000908"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861896.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="HFG9696632.1"
                     /translation="MLRVSNVKLGIDKDISLLKDVILKKLKIKEKNLVKYSIYKESID
                     ARKKGKMEFVYSVDVEVKDENKILNSKIKDVTKIKEIRYVNVPVGDKKLKNNPLVIGS
                     GPAGLFAGLLLAQMGYEPIILERGLDVDSRTKDISDFWTTRKLKNNSNVQFGEGGAGT
                     FSDGKLTTRIKDIRCRKVLEELVQFGAPDEILYSHKPHVGTDILKNVVKNIRNEIISL
                     GGQVRFNSKVTDIVVSNDSIQSVIINDTEKIDTDTIILAVGHSARDTYEMLYSRGIKI
                     VQKPFAIGARVEHPQDLINKAQYKDFYNHPRLGAADYRLIEHVSNGRTAYTFCMCPGG
                     SVIASASNDFEIVTNGMSEHARDKINANSAFLVNVTPEDFKSDNPLAGVHFQQKYEKL
                     AFELGGKNYNAPVQLVGDFINNKTSLNLGSVEPSYRPGYTLTNLSECLPSFVTETMRE
                     AFISLDKKLNGFAMYDAALTGVETRSSSPIRIVRDENTLESVSIKNLYPCGEGAGYAG
                     GIVTAAVDGIKCAEKIIQKYTNNTKI"
     gene            34557..36185
                     /locus_tag="ACGI5H_000909"
     CDS             34557..36185
                     /locus_tag="ACGI5H_000909"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891758.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_function: GO:0005436 - sodium:phosphate symporter
                     activity [Evidence IEA];
                     GO_process: GO:0044341 - sodium-dependent phosphate
                     transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Na/Pi cotransporter family protein"
                     /protein_id="HFG9696633.1"
                     /translation="MNIIISLMGGLGLFLYGMNLMGEGLQKSAGTKLKKIIKLLTSNL
                     FMGVLVGTGVTAVIQSSSATTVMVVGFVNAGIMTLKQAIGVIMGANIGTTVTAQLVSF
                     DLTGMAPVALGVGIILYLFGNKPRIKNIAEILIGFGILFTGMDFMKMAVEPLRDYQGF
                     TDLLVTFGRYPLLGLLLGFGITAIIQSSSASMGMLVALAAEGLVPLSAALPILYGQNI
                     GTCVTSLLSSIGANKNARRAAMMHLIFNVLGTVIFLIFLNKPVVSMVTSWDPSNVARQ
                     IANTHTLFNIISVLILLPFTNLIIKLAIKLVPDRAGDIDEDETKTIKYIDDRMIETPS
                     IALANTIKEALRMGEKAKESLNASMEALVEHSTEKIDKTYRRERLINDLQKAILNYLL
                     KLSKAPLDDDSREVVDTLFNTVNDIERIGDHAKNIAELSQVAIDSNISFSEEGQSELD
                     VMYNRVVSAYTYALESMRTDNVDLACKVIKIEEQVDIMEKSCRANHMYRLNNNLCSIE
                     NGVIYLDVISNLERISDHAVNIAQQVIAKRLGND"
     gene            36450..37799
                     /locus_tag="ACGI5H_000910"
     CDS             36450..37799
                     /locus_tag="ACGI5H_000910"
                     /EC_number="5.3.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435635.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004347 - glucose-6-phosphate isomerase
                     activity [Evidence IEA];
                     GO_process: GO:0006096 - glycolytic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-6-phosphate isomerase"
                     /protein_id="HFG9696634.1"
                     /translation="MGKINFDYSKATEFFCQNEIDVMQPYVDVAHDMLHNKTGLGNTF
                     LGWIDLPKNYDKEEFDRIKKSADKIKSDSDVLLVIGIGGSYLGSRAAIDMVSHSFRNG
                     LKKEQRKAPEVYFVGHNISSTYIMDLLDIIEGKDISVNVISKSGTTTEPALAFRIFKD
                     YLEKKYGKEEARKRIYATTDASKGALRQLATEEGYETFVIPDDVGGRFSVLTAVGLLP
                     IAAAGLDIDAMMKGANDAREAFQNPDLKSNDSYRYAVARTILHRKGKDVELLVNYEPQ
                     LHYVSEWWKQLYGESEGKENKGLFPASVDFSTDLHSMGQYIQDGKRLLFETVLNVENC
                     KRNITISSEEVDLDGLNYLAGKTVDFVNHKAFEGTLLAHTDGKVPNLVINIPQLDEYN
                     FGYLVYFFEKACGISGYLLGVNPFDQPGVEAYKKNMFALLGKPGYEKEKEELEKRLK"
     gene            37955..39034
                     /locus_tag="ACGI5H_000911"
     CDS             37955..39034
                     /locus_tag="ACGI5H_000911"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435637.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="trypsin-like peptidase domain-containing
                     protein"
                     /protein_id="HFG9696635.1"
                     /translation="MSRRKKGISLVILVAIISSILSSFLTIILVKDNLVSKSTGSSTP
                     IVVNDDGKSQNIYQAVAEKATPSVVGITTTSVDTSNMFAIPTETQGVGTGIIVDSNGY
                     ILTNSHVISDGQATSVNVLFNDGSTTSGKVVWFDQQLDLAIVKVDKTGLTPAEFADSD
                     KVKVGDISIAIGNPLGLDFQKTVTQGIISGLDRTIQTEKTNMTGLLQTDASINAGNSG
                     GPLLNQKGQVIGINTAKASQAEGLGFAIPINTAKSIVEEVIKNGKYEKVTLGIKGTDV
                     SNYEAATGTKLSTDKGVYVAEVISGSSAEKAGVKVGDIITKVGDTDITGMNDLNKKLY
                     TFSKGASTKITVNRGGKAVTINVNF"
     gene            39379..40287
                     /locus_tag="ACGI5H_000912"
     CDS             39379..40287
                     /locus_tag="ACGI5H_000912"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728504.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0019471 - 4-hydroxyproline metabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="trans-4-hydroxy-L-proline dehydratase activase"
                     /protein_id="HFG9696636.1"
                     /translation="MNPLVINLQKCSIHDGPGIRSTVFFKGCPLECVWCHNPESQTYT
                     KQVLYNEERCSKCEACINICPHKAIYKGETKICLDQDKCEFCETCLDYCVNNAREIVG
                     QEYSVRDLVKEIEKDRIFYEESGGGVTLSGGEVMAQDMDFICGVINMCKSKGIHVAID
                     TCGYAKSENYERVAKCADLFLYDIKLIDEDKHIKFTGKSNDLILKNVKILSELGANIN
                     IRIPLIVGVNVDDENLEVKKMIEFLKPLNIQAVSLLPYHNIGKHKYDKIYKKYEGEEL
                     QRPSEEKLEEIKRLFEASNFNTKIGG"
     gene            40292..42661
                     /gene="hypD"
                     /locus_tag="ACGI5H_000913"
     CDS             40292..42661
                     /gene="hypD"
                     /locus_tag="ACGI5H_000913"
                     /EC_number="4.2.1.172"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728505.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0019471 - 4-hydroxyproline metabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="trans-4-hydroxy-L-proline dehydratase"
                     /protein_id="HFG9696637.1"
                     /translation="MARGTFERTKKLREESINAEPHISIERAVLMTEAYKKYEGSVEI
                     PVLRALSFKHYIENRTLSINDGELIVGEKGDSPNGAPTYPEICCHTMEDLEVMHNRDI
                     INFSVSEEARKIHKEEIIPFWKKRQTRDKIINAMTPEWLAAYEAGMFTEFMEQRAPGH
                     TVCGDTIYKKGFLDLKKDIEARLKELDFLNDLDAYNKKADLEAMAIACDAMVILGKRY
                     AEKARQMAEEETDEAKKKDLLLIAETCDVVPAHKPETYHQAIQMYWFVHIGVTTELNI
                     WDAFTPGRLDQHLNPFYERDVENGILDRDRAQELLECLWVKFNNQPAPPKVGITLKES
                     STYTDFANINTGGINPDGQDGVNEVSYIILDVMDEMKLIQPSSNVQISKKTPQKFLKR
                     ACEISRKGWGQPAFYNTEAIVQELMEAGKTIEDARLGGTSGCVETGCFGKEAYVLTGY
                     MNIPKILELTLNNGYDPISKKQIGIETGDPRNFQSYEELFEAFKKQLHYMIDIKIEGN
                     AVIENICAKHMPCPLMSTIVDDCIEKGKDYQRGGARYNTRYIQGVGIGTITDSLTAIK
                     YNVFDKKKFDMDTLLKALDANFEGYEAILNLVSNKTPKYGNDDDYADEIMQEIFNAYY
                     NEVTGRPTVCGGEYRVDMLPTTCHIYFGEIMGASPNGRLCAKPVSEGISPEKGGDTNG
                     PTAVIKSCAKMDHIKTGGTLLNQRFAPSVVQGEKGLDNMANLVRAYFNMDGHHIQFNV
                     FDKNVLLEAQKNPQDYKDLIVRVAGYSDHFNNLSRTLQDEIIGRTEQTF"
     gene            42986..43789
                     /gene="proC"
                     /locus_tag="ACGI5H_000914"
     CDS             42986..43789
                     /gene="proC"
                     /locus_tag="ACGI5H_000914"
                     /EC_number="1.5.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898446.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004735 - pyrroline-5-carboxylate
                     reductase activity [Evidence IEA];
                     GO_process: GO:0006561 - proline biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pyrroline-5-carboxylate reductase"
                     /protein_id="HFG9696638.1"
                     /translation="MKTLGFIGSGNMGSAMIGGIVQSGLVKAEDITVSDLSQVALDKV
                     KEKFGVNTTTDSKVAVTNSDVVIVALKPNICEKALTPLKELIDANKIIVSIAAGKTIE
                     SLESFIGSDKKIVRVMPNTPALVGEGMSALCKNSNVTDEELNMIKALFESFGEAEIVS
                     EYLMDTVTGISGSSPAYVFMFIEAMADAAVLAGMPRQQAYKFASQAVMGSAKMVLETG
                     KHPGELKDMVCSPAGTTIEAVKVLEEEGFRAAVIKSIVACIDKSKDMSK"
     gene            44387..47143
                     /locus_tag="ACGI5H_000915"
     CDS             44387..47143
                     /locus_tag="ACGI5H_000915"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893929.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0008134 - transcription factor binding
                     [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sigma 54-interacting transcriptional regulator"
                     /protein_id="HFG9696639.1"
                     /translation="MRDEILSFVNECVLFNNFDELKKESGIITEDIVKKFNLSRTQSS
                     RLLNDLVKSDNLIKINSRPVIFLPKNKINDVVGPTKKSIYENLDELKNECKLLKQETV
                     FNSIIGYDNSLKEVIEQIKTAVLYPNGGLTIMLTGESGVGKTFLAKIIYKYSVSSNVL
                     EKNSPYNVLNCAQYYNNLELLSSLLFGHVKGAYTGANESRAGLIEQSDGGVLFLDEVH
                     RLNSEGQEKLFTFMDTGTFSRIGENGVIRKARVRLIFATTESLSEFLQTFLRRIPINI
                     YVPNIEERGTIEKRKIVEHFIYEESKVLGLPIEITQITLNAILKIKFKGNIGECKNVI
                     KYACGRAYAKNQRRNGNIFVTLQDLPRNLYIENVDIFQFQSGKSKSIIFSPKQFSIEM
                     SNGRNKRNIIYQSFIKCLDYFDRLEKNEITKEKFSKKSSNLMIRLMDNLVFSNNDENN
                     NVLMELIISIMQDIFRNLEVNNNIKYDGNNVLAFSSYLYLKDESYQLSDEYKALENKL
                     LIYLKKESYKEYSIISKISTLITNRLDMYLNNVDIIIMIIFIKSTIIRMKFNQVNATI
                     IAHGYATASSMANVCNRMLGKNIFTAIDMPIDATIADVSKQMSRYLEGDRIKNGLIVL
                     FDMGSLNLIYEDLKNKINSPMLFIDQISTISALEVGNLLMQGKNIEEIAEIMDEETKP
                     NIQLYYPQKNKEYAIISSCFTGIGTAIKIQHLLSESLIGIVDVKIIPYDYDSLVSMGD
                     KEPVFEMYDVMAIVGTANPNVNGVDFILLEDIISGKGEDDVFRIFSRVVENEKIKNIN
                     DSIVKNFSLIRVIDSLTILDSKKIIERIEEGINAIENIQKKKLSNDKKISLYVHLSCM
                     IERLVRQTEIEEYTDMDLLIKNHHSEVKLIKNAFSVLEKSYSVQIPISEIGYIYNIIY
                     GLPQ"
     gene            47275..47754
                     /locus_tag="ACGI5H_000916"
     CDS             47275..47754
                     /locus_tag="ACGI5H_000916"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898441.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system
                     mannose/fructose/N-acetylgalactosamine-transporter subunit
                     IIB"
                     /protein_id="HFG9696640.1"
                     /translation="MVSLMRIDDRLIHGQVAYGWATSLGINVILVANDEAKNDQMKAM
                     SLNLAKPSNVTLYIRGVEESGEIVEKFASSKKSNVLVLVKNTKDALVVAKNSGGVLKE
                     INVGGLRYEEGKKKLTDLVAVDDDDINNFKQIGDLGIDIEFRMLPRDKKKQLSDLIK"
     gene            47770..48192
                     /locus_tag="ACGI5H_000917"
     CDS             47770..48192
                     /locus_tag="ACGI5H_000917"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891752.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:1902495 - transmembrane transporter
                     complex [Evidence IEA];
                     GO_function: GO:0016301 - kinase activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA];
                     GO_process: GO:0016310 - phosphorylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HFG9696641.1"
                     /translation="MKKFLIATHGELSRELVDTSKLIIGSLTNIEYFCMTTDKSADDA
                     EKEIRSILSNNKDSEEFVVLTDVFGGSVANICTNLLLQGFKFELLTGVNLPMLLSILL
                     LVEEDTKLIVKSGLEEAKNGIVYVNELLENQNKIKNVM"
     gene            48232..49023
                     /locus_tag="ACGI5H_000918"
     CDS             48232..49023
                     /locus_tag="ACGI5H_000918"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004453987.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS
                     mannose/fructose/sorbose/N-acetylgalactosamine transporter
                     subunit IIC"
                     /protein_id="HFG9696642.1"
                     /translation="MLVQATMLAIIAGVGILDGRIFGQSMLDRPIVTGMLVGLVLGDI
                     KSGIMIGAQLELIWMGIAGIGAATPPDVVTGGVLGTAFAILSGNGAEVALAVAVPVAV
                     LAQSLGVLVRIINSYFSQKAVFYAKQADFKKVTIMMWLPVILFFLSTSVPTFLAIMIG
                     ADKVTALINAIPKVILDGLGVAGTLLPAVGFALLMDMLLSKKMSVFFFIGFLLASYGG
                     LDITAIALFGVCVAFVLNFYINNKENNQNPQLAINTLTEGEIDFE"
     gene            49016..49816
                     /locus_tag="ACGI5H_000919"
     CDS             49016..49816
                     /locus_tag="ACGI5H_000919"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003432375.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:1902495 - transmembrane transporter
                     complex [Evidence IEA];
                     GO_function: GO:0016301 - kinase activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA];
                     GO_process: GO:0016310 - phosphorylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system mannose/fructose/sorbose family
                     transporter subunit IID"
                     /protein_id="HFG9696643.1"
                     /translation="MNKLTKKELRSMFWRSFALQGAFNYERMQNLGYCYSMLPAIKKL
                     YNKKENQAKAIERHLEIFNTTTVVVPAILGITAAMEEENANNPEFDESSISAVKTALM
                     GPLAGIGDSLFWGTFRIIAAGVGVSLAKEGNIFGPLLFLLLYNIPAFALRIFGLKYGY
                     QVGVNSLERIQREGLMEKIMSMATTVGLFVVGGMVATMLSITTPLKFNLNGAEVILQD
                     ILDKIIPNMLPLTFAFVIYYMLKRKVSVTKLTIGTIVTGIALHAIGLL"
     gene            49864..50919
                     /locus_tag="ACGI5H_000920"
     CDS             49864..50919
                     /locus_tag="ACGI5H_000920"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891749.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0097367 - carbohydrate derivative binding
                     [Evidence IEA];
                     GO_process: GO:1901135 - carbohydrate derivative metabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="SIS domain-containing protein"
                     /protein_id="HFG9696644.1"
                     /translation="MTIQDYMLETPVRMREIISNADSLFNEVKRTNLKKIIITGSGTS
                     YHSGVQVQPYLQNLLDIDVVKMYPFMITEDTFKFDNENTLVVGVSQGGSSYSTYNAMK
                     LAEDKGCKIASMAGCKNALIDEISDYILTVNCGEEKSGAKTKGYYCTKLNLMLLGLQI
                     AREKGIISSEKYNEEINKILDAINRFEAVYKLSKQWIERNKEKLVNSKEIRIIGHSDI
                     YGDTLEAALKLLETMRIPVTGYEFEEFIHGIYNAINSDSTIFILDTGKEPRVTKMIDV
                     LSGWTENVFAIGRDVTENDKNLKIDITDNPYYQTFNFIVPIQLICGEIPTLRGVDPSV
                     PKDTRFHMKLGSKKLNK"
     gene            complement(51098..53044)
                     /gene="feoB"
                     /locus_tag="ACGI5H_000921"
     CDS             complement(51098..53044)
                     /gene="feoB"
                     /locus_tag="ACGI5H_000921"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003432373.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_function: GO:0015093 - ferrous iron transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0006826 - iron ion transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ferrous iron transport protein B"
                     /protein_id="HFG9696645.1"
                     /translation="MINVALLGNPNVGKTTVFNLLTGSNQYVGNWPGVTIEKKEGFLG
                     KEIKVVDLPGIYAMDTFSNEEKVSKSYLENEDVDVIVNVVDASNLSRNLYLTTQLMQF
                     NKPIVILLNMLDIAESKGVNIDAKKLSEELGVIVVPIIAKKKNGVDRIEEEIKGATQK
                     AFIYQKNFGSETETYKKLESILSRCTKTTYTQKKSISDKIDNIVLNPILAYPIFIGVL
                     FLLFKFTFDWVGGPLQEGFASLIEAYISAPVSDMLSNSSPWFKSLIVDGIIGGVGGTL
                     PFFPLIFTLFFGISLFEDSGYMSRTAFLMDKVMRKVGLSGKAFIPIVMGMGCSSPAIM
                     ATRTLESEKDRRVTALIAPLMTCGAKLPIYALFVAIFFPHNAALVTTSLYLVGIVMAI
                     VVALFLNKTAFKTEAEPFILELPEYRIPTIDALIKNTWNKSKGFLIRVVTVMFAMSVV
                     IWGLSSFNVFGYTEDINVSFLATLGHIISPIFKPLGFDDWRTSVAILSGLGAKEIVVN
                     SLNILYGNLTVVLPTIFNGVTAYTFLIFTALYTPCIAALATMKKEYGNKMMFTSFAYQ
                     FILAWIMAFIVKSIGGVLFMGNSIIEALIGGIIIVLALFILFNKFKSTKNGNVCSGCS
                     ICSGCPSANSCSSKEDSNKKNNAH"
     gene            complement(53062..53280)
                     /locus_tag="ACGI5H_000922"
     CDS             complement(53062..53280)
                     /locus_tag="ACGI5H_000922"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417194.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ferrous iron transport protein A"
                     /protein_id="HFG9696646.1"
                     /translation="MTVYDLKIGEKGFINSIDGDIKLSKRLLALGCINSTEIEVKKVA
                     PLGDPIIIRFRGFDLAIRKSDAKNISLQ"
     gene            53486..53995
                     /locus_tag="ACGI5H_000923"
     CDS             53486..53995
                     /locus_tag="ACGI5H_000923"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417195.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Gx transporter family protein"
                     /protein_id="HFG9696647.1"
                     /translation="MKTRKMTFLGLMIGYSLALYVLETYIPNPLIVIFPGAKLGLSNI
                     ITLISLMLLGVKDTVIIVTIRVILSSIFAGPLSYLLFSIGGAYLSLLFMYLASKIKDL
                     SLIGISIIGAIGHNIGQLIVASLIIENILAIGYLPFMLMASLVTGMFVGLVSRYTIPK
                     LKHFYSKFY"
     gene            54073..54234
                     /locus_tag="ACGI5H_000924"
     CDS             54073..54234
                     /locus_tag="ACGI5H_000924"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891746.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartyl-phosphate phosphatase Spo0E family
                     protein"
                     /protein_id="HFG9696648.1"
                     /translation="MANNELEALKNEIEAVREEINTYIEYPEIFQEELVESSKKIDIL
                     INKYMYLSK"
     gene            54385..55050
                     /locus_tag="ACGI5H_000925"
     CDS             54385..55050
                     /locus_tag="ACGI5H_000925"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417197.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MgtC/SapB family protein"
                     /protein_id="HFG9696649.1"
                     /translation="MIDIGSKEIAIRLLLALIIGGIIGLEREKIRQFAGFRTHILIAI
                     GSCIVSITSIQLFFDYNLYTNADPARMPAQVLSGIGFLGAGAILKNKGGVKGLTTAAG
                     MWATACIGIAVGYGYYELAILGGLFVMIALFVLRIINTFLFSQEKNVLILKLSNLDSI
                     PFLYDKFEKNQLIVRNMEIECRNEEYWKVNFFVSYAKRIHLHDVMKEINMIEGVINVD
                     YLD"
     gene            55116..56900
                     /gene="pepF"
                     /locus_tag="ACGI5H_000926"
     CDS             55116..56900
                     /gene="pepF"
                     /locus_tag="ACGI5H_000926"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004453998.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004222 - metalloendopeptidase activity
                     [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="oligoendopeptidase F"
                     /protein_id="HFG9696650.1"
                     /translation="MGTDRSTIEEKYKWKIDKMYSSKEEIEKDISKVKNLIQEVKEYK
                     GKLSESKENLYKVLNISENASRIVQNLYVYTHMKQHEDTRINDNQGRATKTEMLSTDL
                     GVATSYIVPEILAIEENKLSEYLKDEKLSFYAKYIKDILRDKPHTLSEREEEILAATS
                     ELSTIPENVYDMLAYADMEFPEIEDEEGNKVKLSHSNYSLFIKSKNSRVRKDAFEGEF
                     STYEKYKNTFASTLYGGIKSEIFYAKTRKYNSAIEASLFSDDVSLDVYNNLISAIDKS
                     IPNLNKYVELKKKFLGLNEIHMYDLYVPLTDKFDMDIPYDKAQDIILEALKPLGEEYL
                     KVIKSAFDEGWIDVYDNEGKKGGAYSWGSYDSHPYILMSYKNDLNSLFTLIHELGHSV
                     HSHYSRTSQPFLYSDYKIFVAEVASTLNELLLINYLLENSKSKDETIYLLNYYLEQFR
                     TTVHRQTMFAEFEKIVHQRVESGEPLTADEFTNIYYKLNEKYYGKSAIVDKQIGIEWA
                     RIPHFYSNFYVYKYATGFSAASALSQQILSEGSTAVDRYINFLKSGGSEYPLEQLKSA
                     GVDMTKKESIEEALNVFAELVNKLEKEL"
     gene            57152..57994
                     /locus_tag="ACGI5H_000927"
     CDS             57152..57994
                     /locus_tag="ACGI5H_000927"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893923.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA];
                     GO_process: GO:0006817 - phosphate ion transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter substrate-binding
                     protein"
                     /protein_id="HFG9696651.1"
                     /translation="MFKKKIGVLLASTMLVGALAVGCSSNSGGSGDSGDSSKVSVSGS
                     TSIGPLMETIGEKFQEKNQGVSVEVQQIGSSGGIKNAIEGTSEIGMSSRDLKDEEKSA
                     GLKETKIAIDGIALITNTANSVKNLTMDQVKGIYTGKITNWKEVGGNDAPIVIVSREE
                     GSGTRDGFQEIVGFDSEELTKDAQISDGSGNIKTTVEGNENAIGYISFGYVDEKVNSL
                     KINDVEATDANVIANKYPISRPFILVNKEDGLSEKGKALIDYILSDEGQALVSEKGFI
                     KVNQ"
     regulatory      58227..58310
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF01786"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="cyclic di-GMP riboswitch class II; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /bound_moiety="cyclic di-GMP"
                     /db_xref="RFAM:RF01786"
     gene            58890..59567
                     /locus_tag="ACGI5H_000928"
     CDS             58890..59567
                     /locus_tag="ACGI5H_000928"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891739.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000156 - phosphorelay response regulator
                     activity [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HFG9696652.1"
                     /translation="MYNLLVVDDDVDILNINQIYFSNIGFNVYTSETAKDAMDIVESI
                     VLDCIILDISLPDIDGYKMCNDIKEKVNIPIIFLSNYEHEEEKVRGFLAGGDDYITKP
                     YSLKELELRIYARMRQYKNITSVPNVLKFSALVINVNSRKVTFDGESIDLTTMEFEIL
                     LFLAENKEQVFSKIEIYNQVWKMPDIGDQHTVQVHIAQMRKKINSLSREHQYIQTVWG
                     KGYKFVP"
     gene            59639..61654
                     /locus_tag="ACGI5H_000929"
     CDS             59639..61654
                     /locus_tag="ACGI5H_000929"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893921.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HFG9696653.1"
                     /translation="MKKYNILKGTLIVLIVSLLAITGLNLLYKYDNKYTYKSIRASNG
                     ILTIDNDTFTKGKLVFLIDDWEFYNHKIFKPNDFTEQDIKPEYVFIGQYPDFSMRKGT
                     QSPYGNATYRMRIKNEGKDKLLSLELPEIFSASEVWINGEMVSKLGDVGTEKYRPKIK
                     NSVVSFIAKKNTEIIINVSNFSHYYSGLYYPPALGETKDISNMMFYRLLFYSIICFTT
                     FAIAIFSLSVWFLSNKSKIYLYFGCMCVFFAIHVSYPFVHLLGLPLVSFTYAVEDLSY
                     FMVVLCIICINGSISKIEENKVYRFLILPLGITMSIISIVIPIILLPYDMYFVNIYGK
                     LIDIYKYIVFIYILMSSLVSIYKKTCSEHISSYILVSVNTVFGISILFDAVTSNRFEP
                     IFTGWQTEYCGFVIVILFSVMMINRNRIIIKENEKLTRNLEHEVEVRTNELTTLLNER
                     KRFLADVAHDLKAPVSAIQAFIDLIKVGNIHVDEETRTYLYAINQKSNEVQNRVRSLQ
                     EFTSQDKSIGISEKICLNNFIKEIYENNLPDTQACGVNFETYVLEKKIYAKINKEMLT
                     RAFENLIYNALTFTPFDGKIILSMDKEDGFAIIKISDNGKGIPPENIPKVFDRFFTER
                     DNNEPKGQGLGLYIVKSIIREHGGEIFVDSELGKGTVFTIKLSLYFL"
     gene            61704..62384
                     /locus_tag="ACGI5H_000930"
     CDS             61704..62384
                     /locus_tag="ACGI5H_000930"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891737.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000156 - phosphorelay response regulator
                     activity [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HFG9696654.1"
                     /translation="MQTKILIIDGDKDNCKKLKGFLEEKGISIDLAYNCEEAIGKIFS
                     NKYDLIFLEIILSDGDGWTLCKKIRNVTTCPIVYMTYINEDQSILNALNSGGDDYLIK
                     PLNLEILYAKVKAILRRMNSYVNNNENNTKLEEYNRTSGVIKLEDKIIKLTPTENKLL
                     NFFIENPEKTLTTKEIYEHVWMNEYLEDNYSVVVAVNGLRKKIEKDYKNPQKIITIRG
                     AGYYFNKE"
BASE COUNT        25371 a         6736 c        11140 g        19328 t
ORIGIN      
        1 ataataagat tgaatccata gaaagtttta tagatgatta tagtaaagca ataaattttt
       61 ttgcaaagaa taaaaaggta ttaatttcaa ctataatagt aacttttatt caattaagtg
      121 cttactttag tgtttcattt tggatatata aagcatttaa tttacaaggt tatagctata
      181 tttatatact gacattacaa gcatttttat atatggcaat atctccaata ccaacacctg
      241 ggaatgtagg agctaatgaa ttagcctttt tcactatatt caaatcagta ttccctcaac
      301 ctttgatggg atatgcagta tttttatatg gtggatttat gtactatttg attctgattg
      361 gaagtggaat atttactgta attactcact atagaatgaa aaacagaatt ggcagaaata
      421 ttgttttaag tgaaaactaa ataagtttaa agaatatata ttgagtatat taaaaaatat
      481 gtcataagaa ctagaatatt ttaattaaat ggttgaaata taaagattat tatgacatat
      541 tttttttgaa atttaagagg aattgtgaga aaattgttga atttaataga tagtattgca
      601 aaatatttat gattttgcat attataaaaa cactcattat ctttaagata aattttactt
      661 atcaggggat aaatctaagg ggggaattgt atggagaaaa aaattttaac agtttgtcca
      721 tactgtggag ctggatgcca attatatcta gtagtaaaag ataataagat attaagagct
      781 gaaccggcta atggtagaac aaatcaagaa agtttgtgtt taaaaggtcg ttatggatgg
      841 gattttctaa atgaccctaa aattctaaca cctaggctaa aaaagccaat gataagaaaa
      901 caaggtgtac tagaagaggt tgaatgggat gaggctataa actatacagc ttcaagacta
      961 aatgaaatta aagaaaaata tggacctgat tctattatgg gaacaggttc tgcaagagga
     1021 cctggtaatg aagcaaacta tataatgcaa aaatttatga gagctacaat aggaactaat
     1081 aatgttgacc attgtgctcg tgtctgacat gcaccatctg tagccggtct ggcttactca
     1141 ttaggtagtg gtgcaatgtc taattctata ccagagatag aaaatgcaga tgttttattt
     1201 atatttggat ataatggagc agattcacat ccaatagtgg caaatagaat agtaaaagct
     1261 aaaaaaaatg gtgctaaatt aattgttact gaccctagag taactgaatc tgcaagaatt
     1321 gctgatatac atctacctat aaaaggtgga acaaacatgg ttttagtaaa tgcttttgga
     1381 aatgtattaa tagaagaagg tctttacaat aaagaatttg ttcaaaatca tacacaagga
     1441 tttgatgagt ataaagaaat tgttaaacca tatacagcta aatatgctga aaagattaca
     1501 ggaatcccag aagagcttat aagaaaagct atgagagaat atgcaaaagg taaaaaagct
     1561 atgatacttt atggaatggg tgtctgtcaa tttggtcaag ctgttgatgt agttaaggga
     1621 cttgcatcaa ttgctctact tacaggtaat tttggtagag aaagcgttgg aataggacct
     1681 gtacgtggac aaaataatgt tcaaggagct tgtgatatgg gagctcttcc taatgtatat
     1741 cctggctatc aaaatgtaac tgatgataag ataagagaaa agtttgaaaa agcttggggg
     1801 gtaaaattat ctcctaataa tggttatagt ttaactcaag ttccaaattt agtactaaaa
     1861 gagaaaaagc ttaaagctta ttatatattt ggagaagacc cagtgcaaag tgacccagat
     1921 gcatcagaag ttagagaagc attagatgaa ttggaatttg tcattgttca agatatattt
     1981 atgaataaga cagcacttca tgctgatgtt atacttccag ctacttcttg gggagaacat
     2041 gagggagtat atacatgtgc agatagagga ttccaattga tgagaaaagc tatagagcca
     2101 caaggagatg taaaaccaga ctggcaaatt ataagcgaaa tttctacagc aatgggatat
     2161 cctatgaatt ataaaaatac taaggaaata tgggacgaac ttagacaatt atgtccaagt
     2221 ttcttaggtg ctacttatga aaagatagaa actcaaggat gcgttcaatg gccttgtaag
     2281 agtgaaagta tggaagataa aggaactatg tatctgtatg aaggtcaaaa gttttctact
     2341 cctaatggta aaggtaattt gttcgctgct gaatggagac cccctatgga agttgaagat
     2401 gatgaatacc catttagttt atgtactgta agagaagttg gacactattc agtaagaaca
     2461 atgactggta attgtagaac acttagttca ttagaagatg aaccaggacg tgttcaaata
     2521 aattctaatg atgctgaaaa attaggaatt gaagatgatg aattagttag aattagttca
     2581 agaagaggaa gtgtaataac aagagcaaca gttactgata gagttaagga aggtgcaaca
     2641 tatatgactt atcagtggtg ggttggagct tgcaatgaac ttacaatagc aaatttagac
     2701 cctatatcta aaacaccaga gtataaatat tgtgctgtta aacttgaaaa acttgaagac
     2761 caagaattag cagaaaaatg tgtaagagaa gagtatcaaa gtttgaaaga caaaatgaca
     2821 gctacaaata tctaatgatt tattagattt aagatttata aaaggcagaa aggctaatat
     2881 tttatgaaca atatatactc aaaaactaaa ttacaagaaa atagtaagga taaagttttt
     2941 gaaaatagtt atagtctagt ggactacaaa tatttaaatt cttttaatgt agaagtaagc
     3001 aaaataaatg aacatgaagt atcaatagat aatgaagaaa taattgcaga atatccactt
     3061 agttttattt taaatgataa atatgtaaat acatttttat gtaccccata taatttagag
     3121 gaacttatag taggattctt gaaaacaaaa ggatacatag aaaacaaaaa aagcttatta
     3181 aaatttgaga taaatgagag tgaacgtttt gcaaaagtaa ctattcaaga gaaacaaaaa
     3241 aatcaagatg agcaaattat atttttaaat tcactagact atataacatg tgctcctgta
     3301 aagagcaata taaaaataaa ttatgatacg atttacagta taatggataa aaatttaaat
     3361 tcatcagaat tatttaaaaa tactggtggg gtacatagcg tatctgtatt taattttgat
     3421 aaaaaaatag tcacttgtga agatgtagca aggcataatg caatggataa ggctattgga
     3481 ttttgtgttt taaatgacat aacattaaaa gataaaattg tggctgtaag tggaagaata
     3541 tcattggaaa tgatattaaa agcagctatg actcaaattc ctattgtagt atcaaaatca
     3601 gcaccgacta atttatcaat agagctttct aaaaaattaa atataacgct tattggattt
     3661 gtaagaggaa gacggatgaa tatttatgca aatccacaga gagttatcaa aaagtgagaa
     3721 tgaatatatg tgtactaaaa aagaagagca aagatattca aagtgtgaaa tctgtggagt
     3781 attaattgat gatactgata aggtgtataa taacacatac aatttgtgca aaaaatgtaa
     3841 acgaaatata agtactgaga aaatagtgaa atatataaat atatatgatg aaagtaagta
     3901 gacatatgat gaaaataact agagggttgg aaatatacaa attgaaaggt gggataatat
     3961 gaaaaataaa ataggctctt ttgtaatagc agacccaaac aaatgtacag gttgtagagc
     4021 ttgtgaagta gcttgtttta caatgcataa tcagcataat aatgtgggtt atacagttgg
     4081 aacagttgat atacctgtta tacctagact ttacttagta aaaggtgaca atttctgtat
     4141 gccaatacag tgtagacatt gtgaagatgc tccttgttta aactcatgtc cacaaaaagc
     4201 tatagttaaa gaaaacaata ttatgtctgt aaatgaagaa aagtgtatag gatgtaaaac
     4261 ttgtctgcta gcatgtcctt ttggagctat agacttactt ccacaatatg aagatggtaa
     4321 agaagtagaa caagtaattt tagatgaaaa taagaagata gcttataaat gtgacttatg
     4381 taaagacaat gaaaaaatag cttgtataag tgcatgtcct caggaagcat taaaacttgt
     4441 tactccaata gatgacaaaa aagctaagaa tagacaagct gcacttagtt tattgttaac
     4501 aaataaataa aggatacagg ggtaggtgac gtttatgata ataaatatag ataaggattt
     4561 atgtactgga tgtagagaat gttcaaaggt ctgtccagta aatgctattg aaggtgaaga
     4621 gggaaagcca caagagataa atttagatag atgtgttatg tgcggtcaat gtgttcaaac
     4681 ttgtaaatct tatgcctcag ttatagatga aggatttgag tttttacaag agaaaaaaca
     4741 agaaagagag ataccagagt ctataaatga acctatattt gcagcataca atgtatgtga
     4801 tatagataag gtgaagaaag ctttaagtga cccaaatgta ttcactatgg tccaatgtgc
     4861 accagcagtt agagttgctt taggagaaga ttttggatat tatttaggat acttaggtgc
     4921 tgggaaaatg gcagcagcac ttagagcttt aaattttgat agagtctacg atactaattt
     4981 tgcagcagat ttaactataa tggaagaagg tagtgaatta attaaaagag tgacagaagg
     5041 tggaactctt ccaatgttta catcttgttg tccagcttgg gtaaaattca tggaaaaaaa
     5101 ttatcctaaa ttaactaatc atttatcttc ttgtaaatca cctcagcaga tgggtggtgc
     5161 aatatttaaa acttatggtg cagagataaa taatgtagat gcatcaaaga tatttagtgt
     5221 ttctataatg ccatgtacat gtaaaaaata tgaatgtgat agagaagaaa tggattctag
     5281 tggatataga gatgtagatg tagtattaac tactagagaa ctagcttatt taataaaaga
     5341 catgggaatt gattttaaaa atttaagaga agaaaaattt gatagtcctt taggtagtta
     5401 tagtggagct ggaactatct ttggtgttac tggtggggtt atggaagctg ctataagaac
     5461 aggatatgag cttataactg gagaaagtat tcctgatgta gaagtaaaac aagtaagagg
     5521 agaaaatggt tttagaaagt caactattaa aataggagac ttagacttaa gagttggagt
     5581 agtaagtgga ttaaaaaatg taataccagt tcttgaagac ttggaaaaag gaaaattaga
     5641 tgtagatttt attgaagtta tgacttgtcc tgttgggtgt gtaagtggtg gaggtcaacc
     5701 aaaaatttta ctagaagaat ataaggaatt ggcttatgaa aatagaacaa aagcaacata
     5761 cgtgcatgat gaacatttag caattagaaa atctcatgag aatcctgata ttaaaaaact
     5821 gtatgatgaa tatctggtag aaccattagg agaaaaatct catcatctat tacacactac
     5881 atattgtata ggaaaggaag tggctaagtg atgaactatt ttgttatagc agaccctgat
     5941 aaatgcatag gatgtagaac ttgtatgata ggatgtgtag ttgcacattc agatgaagat
     6001 attttttacc aaaatccaga tgaaataaat tttaatccaa aactttctgt cataaagaca
     6061 aaagaagtaa gtgctccaat acagtgtaga cattgtgaag atgctccttg tgcaaaggca
     6121 tgtccaaatg gtggtatagt tagggttggt aacacaataa aaataaatga agaaaattgt
     6181 ataggatgta agacttgtat gttagcatgt cctataggtg caatagacat agttacatta
     6241 aaagatgtag atgaaggaaa gctttgcttt agagaaagaa tgacagcaaa taagtgtgat
     6301 ttttgtatag aatcgccaga agggcctgca tgtgtaaatg tttgtccaac taaggcattt
     6361 actatagtta aggatgagga tatagatagt aaagttaaaa ataagagaaa attagctata
     6421 ttgtaatata aaaaagatgg agttttattt atgattaaaa gctccatctt ttttattata
     6481 atatttatat atctaaaaat caattattgc attagtttat ctaatctttc tttattcaat
     6541 tttttcattc ctatagaagt tataataagt aaagtatagg caattataac tgataaaatt
     6601 ataatagacc aagaaaatct gtatccaaaa ttatcaacta acaatccaaa taatgttgaa
     6661 cctaatgcaa atcccactgc aaaaattaat tgtacgattc catatatgct accaaactcc
     6721 ttttgaccaa agaaagagcc agttaaataa gcaggaccaa tcatataagc aaatacagaa
     6781 agacctttca aaatggcaaa tacaaatgca aaagtagaag atttatctac caatagtaat
     6841 gataaagttg ctataagaac caatacaaaa gatataataa gtggctttgt ttgaccgaat
     6901 ttatcaaaca ataatcctcc aaataaatta ccaatgagag caaataaggc aaatgtggag
     6961 cctactgttc ctattagaat aggatttaga taatttctaa gataagttgg atattgtaca
     7021 gataatgatg aaacatatat accaacaaat ataaatccaa tagtcataat ccaaaaatat
     7081 ttaatttttt tagcttcttt taatgtataa ccccatactg aaggagaaat tgtatcagat
     7141 gctttctctt ttttaccttt agattttacc ttttcattaa tatctttagg catcctgagt
     7201 atgaataata ttacaggtat accaactatt aatgctataa ttccaaatat tagataagaa
     7261 cgactgtatc cttgagttgc taataagcga actgcaagtg gttgtagaaa tatactacca
     7321 atagaaccac cagcaaaagc aaagcccaaa gcttttcctt tgctttcttc atcaaaccaa
     7381 gcacttatta aaacaggtat tcctatagca gatataattg tagcgccaat ttgaacaata
     7441 catgatacag tgtaaaattg ccatagttca gtacatatag aaaaagtagc aaaagcaata
     7501 ctagaaatta tacaacctaa taaatatagt atcttaatat tgactttaga aaataataca
     7561 cctataaaag gtgatgcaat tgctgaggca atagtaccaa tagtgaatat tagagaaaaa
     7621 gaagctaaac taaagccttc tccttctaca acataactta taaattgagg ctgtatactt
     7681 gctacaatac taaatggaac agcttgtatt aacatacaac caagtactat aacccaagca
     7741 tttgaaaagt ttttaatgct aaatttattg tttagtaatg tattcatggt atctctcctt
     7801 taggttatga tttgtagata ttaatctaat tattctaatt ttatatatta gttttggata
     7861 gcctaactat ttaaatataa tttgggtatt aatataaaaa ttaactataa aaattgatta
     7921 ttttaaatgt atggggtaaa ttaaagtata taaataaatg aaaggatgga taaaatgtca
     7981 tttgaaaaaa taaataataa taacctagat aaaatacaca ataggaagtg tattatgctt
     8041 gtaaacttta ataaaaaaga attatcatta attaaaaatg taagtaactt tgctggaata
     8101 agagaccata tcatcttaag tgataaaaat ggagagaata taataagaga cattttagat
     8161 ggaaatatat caaatgaatg tgaaaatggg attaagagta agtctgtaat atttaataac
     8221 actccaagta cacaagtaaa tgcattttta gaagggctaa aaaaagtgag aataaataga
     8281 ccttttacag ctatggtaac agagacatct attgattgga cattgaataa tttaatagaa
     8341 aatttagttc aagaacgtaa tgctatgtct ttaggaaaaa caattgaaca taagtaaatt
     8401 taagatatct tatagtaatt ttaactaatg tacattgagt atcatattat attttagaat
     8461 agaaaatttt aaatgtgggt agatggagga gatttgagat gaaagtttta tttacaataa
     8521 attatggaaa agaaaaattt gataaaataa gagaattagg ctatgatgtc atacattact
     8581 ctgaagatag tattgaaaat aatgaggatg taaatacagc agatgtacta gttacataca
     8641 atccatttga gagattagat atttctaaga tgaaaaattt acaatatata cagacaacta
     8701 gtgtaggtat agaccaactt ccaaaagaag aggtattgaa gagaaatatt aagatagcta
     8761 ataatagagg cggatatagt gtacctattg gtgaaagtat tgtattgtat attttagaaa
     8821 tatataaaaa tagtgcaaaa ttttttaaac aacaacaaaa taaagaatgg aagatggatt
     8881 tttctgtatc agaattgtat ggacaaagag ttggattttt aggaacaggt actatatctt
     8941 cagaagcagc aaaaagatta aaagcttttg gtgtagaaat atggggtgtc aatactgatg
     9001 gaagtagtaa aaaatacttt gataagtgtt ttgctactga ggatatgaat attgtatttg
     9061 aagaatgtga tatagtagtt gtagcaatgc cttctacaaa aagtacagat ggaatagtaa
     9121 acaaagatat gtttaaactt atgaaagatg gttctgtatt tataaatgta ggtagaggaa
     9181 atacagttaa tcagaaagat ttagaagaat gtgtagagaa atttagaggg gtagcattag
     9241 acgtatttga aagtgaacct ttaaacaagg acaataagtt gtgggagtgc gaaaatgtca
     9301 tagtaactcc tcataattct tgggtgtcag ataaaaacaa agagagaaca tttaatatgg
     9361 tttataataa tttgaaacac tatataatgg agaataaacc tgtagataat gttgtagaca
     9421 tatcaagagg ctattaaaaa taaaaaattt tgataaaaat aaaaactctt attagtcgta
     9481 ttaaagatac taataagagt tttttttgta ataaatttaa agcccaaaaa gtgatatact
     9541 aaaaaatata taaataggag ataattaatt atagggaaat ttcaaaataa tttaatttta
     9601 aaaatatgaa gaggtgcaaa aagtgagcgt aaaagatgaa attaataaac ttatagagac
     9661 aataaactac cataatgaaa ggtattataa tcaagatagc ccagaaatat cagattatga
     9721 atacgataag ttaatgaagg agttaatttc tttagaagaa gaacatccag aactaaagag
     9781 aattgattct ccaacaaata gggtaggagg taagccatta gataagttca atcaaattgt
     9841 acataaaact cctatgttga gtttatcaaa tgctttttca gagcaagatt tgagagattt
     9901 tgataagaga gttcaagaat atgtgggaga aaatgttgaa tatgttgttg aatttaaaat
     9961 agatggtctt tctgtaggtc taacttataa caatggagag tttgaaaaag gagcaactag
    10021 aggagatgga gttgtaggag aagatatttc tcaaaactta atgacagtaa aaagcatacc
    10081 tcttaagata aatgataaaa aagaactaat agttagagga gaagtatata tatcaaaaga
    10141 taattttaga aaagtaaatg aacaacaaga agaacaagaa cagccattat ttgctaatcc
    10201 aaggaatctt gcagctggtt cattgagaca attagaccca aaactaacag caaagagacc
    10261 attagatata tttgtattta atatggaaaa tatagaagaa tacgatttag aaagtcacag
    10321 tgaatcacta gagtacttag aaaaactagg attttcagta agtcagagtt ataaagtttg
    10381 taaaagtata gatgaagtta ttgagcatat tgaatactgg acagataaca ggggtaattt
    10441 agactacgaa atagatggta tggtaataaa agtaaacaat ataaaacaaa gagacgaaat
    10501 gggatataca gccaaaagtc ctagatgggc aattgcatat aaattcccag cagaaaagaa
    10561 gaaaactaaa atagtagata taatagtaga agttgggaga actggtacaa taacaccttc
    10621 agcaattctt gaaccagtca gacttgcagg taccactgta agtagagcta cacttcacaa
    10681 tgaagattat ataagagaaa aagatataaa aataaatgat acagtattag ttcaaaaagc
    10741 aggggacata atacctcaag ttttagaagt tataaaagaa gaacgtactg gagatgaaat
    10801 agattttaaa atgccagaaa agtgtccagt ttgttcagag ccaacaataa gattagaagg
    10861 agaagctgct gtaaaatgta tcaatatgtc ttgcccagcc caaataagaa ggggaattat
    10921 acactttgtg tcaagggatg caatgaatat agatggattg ggagaatcta taattacact
    10981 gctattaaat gaaaaaatta ttcaagatgt atctgattta tattatataa aaaaggaaga
    11041 tgtagtcgac ctagagagaa tgggcgaaaa atctgctgac aatttaataa attcaattga
    11101 aaaatcaaaa gaaaatgatt tatggagact tataaatgga ttaggtatta aatttatagg
    11161 agttaaagca gctaagatac ttgcatataa ctttaaggat ttagatgaag taatttctgc
    11221 aactagtgag caactagaag aattagagga atttggaagt ataatggcaa acagcgttgt
    11281 cgagtttttt aaggaagaca aaaatatgaa cgttataaac aagttaaaaa atgtaggagt
    11341 aaatacaaaa tcattggata atacaggtga aaaagtagaa aaaatatttg aaggtatgaa
    11401 aatcgtattg actggtacac ttcctacatt aaaaagaaat gatgcaaaag atatgataga
    11461 aaaaagaggt ggaaaagcta catctagtgt tagtaaatcg acaacatttg ttttggcagg
    11521 tgaagaagct ggttctaaac ttactaaagc aaatgattta ggaattaaag ttatagatga
    11581 agagagattt ttagaattat taaagttatc atcgaaagat gaagtaaaag ctgtattaga
    11641 gagttaaaaa gtcgcttaat ttagtagaaa actactataa ttaatgatag aatagttcag
    11701 taagctaata agattacgaa aaatgacaat aattaatatt tgacaaaatt aaaaattata
    11761 aaaataaatt tataaaaaat aaaaaatatg agaaaggata taaaaaatga ccagaagtta
    11821 tgatagaagt aatgaacaga taagacctgt aaagataact agagattata caaagtatgc
    11881 agaaggttct gttcttatag aaatgggaga gacaaaggtt atatgcactg catcagtgga
    11941 agaaaaagtt cctccttttt taagaaatag tggtactgga tggataaatg ctgaatattc
    12001 tatgctacca agagcaacac aacaaagaaa gataagagat gcatctaggg gaaaaattga
    12061 tggaagaaca caagaaatac agaggttaat aggaagaaca ataaggtctg ttgtagactt
    12121 gaataaatta ggagaaagaa ctatttgggt agattgtgat gtgattcagg cagatggtgg
    12181 aactagaact gcatctataa caggggcatt tgtagcagtt gcagaagcaa tatataaatt
    12241 atataaagca aagacaataa aagagatgcc aataacaaat tttgtgtctg caattagtgt
    12301 tggtattgta aatggaatac acatgctaga tttatgttat gaagaagatt ctaaagcaca
    12361 ggtagatatg aatataataa tgactgataa gtgtgagttt gtagaagtac aggggacagg
    12421 agaagagaaa cctttttcta gagcagattt aaatttattg ttagagttag gtgaaaaagg
    12481 gaataaagaa ttaataaggc ttcaaagaga agctttaggt gaaatatcag atgagatatt
    12541 gggtatggat tatggtaatg aagtagtgat tgctactaat aatgctcata agctagaaga
    12601 aataggtgaa atcttaaaag attttgaata taaagtgtac tctttaaaag atgttgattt
    12661 agcaggtata gagatagtag aagatggaaa aacatttgag cataatgcgt tgataaaagc
    12721 tagaacaata gcaaaaaaga ctaaacttat agcaatatca gatgattctg gcttagaagt
    12781 agatgcttta ggcaaaaaac ctggtgttta ttcagctaga tatgcaggag aacatgcaac
    12841 agatgaagaa aatagaaaaa aactgttaaa agctatgcaa aatgtaccaa tgagcaaaag
    12901 aaatgcaaga ttcgtctctg caatagcagt agtttttcct gatggaaaag aatttgtagt
    12961 aagaggaatt tgtgaaggaa tgataggatt tgaagaaaaa ggtaaaaatg gttttggata
    13021 tgatagctta tttatagtaa aaggatatga taagactttt ggtgaaatac ctagtgttat
    13081 aaaaaattca atcagtcata gagcaaacgc actaaaactt atgaaacaag agtttataaa
    13141 aagggtagtg aagtaatgaa aataggcata gtaagcgaca cacatatgat gattaaaaat
    13201 atggaaaaaa caataccata tttgaaagaa tgtgacctaa taattcatgc aggagataac
    13261 tttactgatt caagatatat tcatagcatg actaatgtag gtattattgc agttaaaggt
    13321 aattgtgact ttgatgctgt tgaggaagaa gttgtctttg aagtggcaaa taaaaccata
    13381 ttcttatgcc atggagataa gtatggtgta aaatatggaa ctaatatgtt agaaaaaaag
    13441 gcaactgaag ttgatgctga tatagttata tttggccata cccatacccc atttagagaa
    13501 attaaagatg gtgtacttta cataaatcct ggaagcactt cacttccaag aggagtatcg
    13561 tataaaagtt ttgtcattat ggatatagaa gaagatgaca taaaaattga agaaatacgc
    13621 atataaaggt gtatttatct aaaaaaatgg caaaaaacgc tcaaaaaatt aaattttatc
    13681 aaataagtac aacgatatta atggaacact tgtaaataaa aaaacttatg tgatataatt
    13741 aagtggttga attataaata gaatgaatta taataccgtt atcgggtatt acataaatat
    13801 cactaggagg attagaagga tgaaagcaga actaattaaa aaagagggta ataaagttac
    13861 tttaaaaata acagtagata acaataaatt tgaagcagca gtaaataagg cttataataa
    13921 aagcagaaat aaatacaata tacctggatt tagaaaaggt aaagctccaa gaattgttat
    13981 agagactcaa tacggaaaag gtatattcta caatgatgct atagaaatat tattcccaga
    14041 agtttatcca gaagctatca aggaattaga catagaccca atagacaatc cagatttaga
    14101 tatagaagaa ataagtaaag acaatgggtt ggttatggtt cttaatgtag aagttaaacc
    14161 agagtttgaa ttaggaaact acaagggtat agaaatagct aaggttgaga atactgtaag
    14221 tgacgaaaat gttgatgcta aactacaaga aatggttgaa aaaaatgcca gattagtaag
    14281 tgtagaagac aaagctttag aagatggaga tacagctata atagacttcg aaggttttga
    14341 aaatggtgta gcttttgatg gtggtaaagg tgaaaattat aacttagtta taggttcaaa
    14401 cacatttata ccaggatttg aagaacaatt agtaggtaaa aaagctggtg aagaagtaga
    14461 agttaatgtt actttcccag aagaatatca ctcacaagat ttagctggaa aaccagttgt
    14521 atttaatgta aaaataaatg atgtaaaagt aaaagaatta tctgcacttg atgatgaatt
    14581 tgctaaagat actagtgaat ttgattcttt agatgaatta aaagcagatg taagagctaa
    14641 gttagaagaa gaagctaaaa atagagcaga tgcagaaact agaaattcag tagtagaaaa
    14701 agttgctgaa aatacagaaa tagaaatacc agaagttatg atacaacatc aaatagataa
    14761 tatgttaaat gaacttaact accaattaca atatcaagga tttggattac aacaattact
    14821 agagatgact ggtagaacta tggaagaatt aagagaagag agaaaagaag atgctaaaaa
    14881 attagttaag tcttctttag tattagaagc aataactaaa gctgaaggaa ttgaagcaac
    14941 agaagaagaa tttaaggctg agttagaaaa aatggcttct gcttacaata tggaagtaga
    15001 aaaaatagaa gcttctttaa gagatgctga caaagaagat ataaaaggtc aaataaaaat
    15061 aagaaaaaca atagatttat tagttgataa tgcaacaata gcttaataaa ataaacgcta
    15121 actaatatag ttgacgttat gaaatgttta gtatataatg atgtgcaaat ataatttagt
    15181 taaatgcgta taataattta cagtagctta aaaaaagcta ctgtaaatta tatagaataa
    15241 agggggtatg aaaccatggc attagtacct gtagttgttg aacaaacagg aagaggagaa
    15301 agatcttatg atattttttc tagactatta aaagacagaa taatcttctt aggagatcaa
    15361 gttaacgatg ccacagcagg gcttatagta gcacagctat tatttttaga agctgaagac
    15421 ccagacaaag atatacattt atatataaat tctccaggag gaagtataac ttctggaatg
    15481 gctatatatg atactatgca atacatcaaa ccagatgtaa gtactatatg tataggtatg
    15541 gctgcttcta tgggagcatt cttgttggca gcaggagcaa aaggaaaaag actagcacta
    15601 ccaaatagtg aaataatgat acatcaacca ttaggtggag ctcaaggtca agcaacagat
    15661 atagaaattc atgcaaagag aattttaaaa ataaaagaaa ctttaaatga gatattatct
    15721 gaaagaactg gtcagccatt agaaaaaatt aaaatggata ctgaacgtga taacttcatg
    15781 agtgcactag aagccaaaga atatggttta atagatgaag tatttacaaa gagaccgtag
    15841 atagagagag gtgttaatat gtctaaatat gaagaaaaac gacaattaaa gtgttcattc
    15901 tgcggtaaaa atcaagatca agtaagaaga ttaattgcag gtccaaatgt atatatttgt
    15961 gacgagtgtg ttgaactttg tgacgaaatt attcaggaag aaatagaaga tactatagat
    16021 gaagatacta catctttacc aaaaccaaag gaaatgatgg agattctaaa tgattatgta
    16081 ataggtcaag aaaaagctaa aaaagcttta tcagttgcgg tttataatca ttataagaga
    16141 atatacagta aaaaatctag tagtaaggat atagaaattc aaaagagtaa tatactttta
    16201 ttaggaccta caggttctgg aaagacatta cttgctcaaa ctctagcaag aactctaaat
    16261 gtaccttttg caatggcaga tgctacatca ttgactgaag ctggatatgt tggagaagac
    16321 gttgaaaata tacttttaaa acttattcaa gctgctgatt ttgatataga aaaagctgaa
    16381 agaggtataa tatatataga tgagatagat aagattgcaa gaaaatctga aaacccatct
    16441 ataactagag atgttagtgg tgaaggtgtt caacaagcac ttctaaaaat attagaaggt
    16501 actgttgcaa atgttccacc acaaggagga agaaaacatc ctcatcaaga atttttaaag
    16561 atagatacta ctaatgtatt atttatatta ggtggagctt ttgatggatt agagaagata
    16621 attcaaaaac gtggtggaga taaaacacta ggttttggag ctaaaataga aagtaaaaaa
    16681 gaattagatt tagggaagct gtatgaaaaa gtacttccag aggatttatt aaaatatggt
    16741 ataataccag agtttatagg aagaatacca gttttagcta ctttagagtt gttggatgaa
    16801 gatgcattaa tgcagatatt acaggaacct aaaaatgctc tagtaaaaca gtataaaaag
    16861 ttattggagt tagatgatgt tgagctagaa tttgaagaag gtgctcttcg tgcaatcgct
    16921 aaaaaggcca tagaaagaaa tacaggagct agaggactta gaagtatagt tgaaagcgta
    16981 atgatggaaa ctatgtttga agtaccatct agagataata taaagaaggt tatagtaaca
    17041 gagaaatctg tgaacgaaga ctcagtaaat cctatcatag tacttaagga tcaagaggaa
    17101 agtgcataag atgatgaaaa ggagctttaa aagctccttt ttttatgtta atatgctaaa
    17161 tataaaatag gtatcattat tataaaaatg tgagtaatat acctagaata ccaaagacga
    17221 atacaattgc aatggaacca atttttcctt tatataaaag ataaaatgat gctataaatg
    17281 caattattcc atataaatcc caattaactt ctttggcaga tgaaaaagct gctgataata
    17341 tgaatcctag agtaattggt ctaagaactg tcaataagtt ttctaccttt ttattatttt
    17401 taaatttaga aaataacttt gatataatag ttagacctat taatgcaaaa attgtaacac
    17461 caatagttgc agctagagaa ccaaagaagc cagcagtctt aaatcctaca aatgtagcac
    17521 tatttattgc tacaggacct ggtgtagatt gtgatatagc aagtaaatcc aaaaactctt
    17581 gattagttat aaagtgatat ttagatataa attcttgctg gataaatggt agcatggcat
    17641 aaccgccacc aaaactaaat gcccctattt taaggaatat taagaagagt agtattattt
    17701 ctgacataga ctatatacac ctcctccaat tattaaataa atagggctta tattgaatac
    17761 accaacagat aaaactgcta taattaatag tagtatgtta gttttagact ttggtagttt
    17821 cttgaacatg ctcgtaaaag aatacaatat aagagctatt acaacaggcg caactccttt
    17881 aaaaaatcca tctaaaattt tagatgatga atttttaaag tatagatacg ataagactaa
    17941 gactatacaa aatgatggta aagcagagcc taaggtacat ataagaactc ctggtatacc
    18001 ataaagttta tatcctaata atacagatat attaactgcc agtactccag gataactttg
    18061 agctatggat aaataatcaa taaattcttc ctgctctaaa agtttttgtt tgtttacaag
    18121 ttcatcttgt ataagaggaa ccatagcgta tccaccacca aatgtaaacg caccaatttt
    18181 taaaaaggtt aaaaacaatt tcaacataat agaaacctcc aaaagataaa taacatctaa
    18241 gtatactaat attaatatta tatcataata aaaagataat atagtatgat agtattctaa
    18301 gaatttatca ttaatgttga aaattaactt gttcaaatat ataatattaa aagcaaagca
    18361 attagactag aaaaggagta atgttgatgg aacaaaatta tactaaaata gatcatgaat
    18421 taccattaat tcctctaaga ggattagcta tatttccata tatgatatta aattttgata
    18481 taggtagaga gatatctctt aaagctttag accaagctat gatggatgaa gaacttatat
    18541 ttttaacttc tcagaaagaa gcagaggtag atgagccagg agaagaggat ttttatcatg
    18601 tgggaacaat ctgtaaagtt aagcaaatga taaaattacc aggagataca gttcgtgttt
    18661 tggttgaagg tgtatcaagg ggtagagtaa agaaaataga acaagaagat gggtatttca
    18721 gagcagtaat agaagaaata gtatttgata gtgataattt ggatagtgaa acagaagttg
    18781 aaattgaagc atttgtaaga aatgtatttg atgcctttga agagtatata aatattggaa
    18841 atagggtatc accagaaata ttaatatctt tagctgatat agaagatgta gatagattta
    18901 tagatacgat agctgcaaac atatatctaa aatcaagcca aaaacaagaa atattagaag
    18961 aatttgatat tagaaaaaga cttgaactta tttattctat attattagag gaaatagata
    19021 tattaaaaat agaaaagaaa ataactttaa gagtaaaaaa acagatgaat aaggttcaaa
    19081 aagaatatta tcttagagaa caattaaaag ctatacagaa agaattaggt gaagaagaag
    19141 atataaactc tgaagcagat gagtatagag aaaagcttaa aaaaataaaa gcacctaaga
    19201 caactaaaga gaaaatagaa aaagagatag ataaattttc aaaaatatct tctatgtctc
    19261 cagatgtatc tgtaagtaga aactatttag atactatatt ctcattgcca tggaataaag
    19321 agacaaaaga taaattagat ataactaagg caaaagatat attagatgaa gaccattatg
    19381 gattagaaaa agttaaggag agaatactag agtatctagc tataagaact cttgctaagt
    19441 cacttaaagg gcctataata tgtctagttg gtcctccagg aacaggaaag acatctatag
    19501 taaaatcaat cgccagagca ttaaatagaa aatttgtaag aatatctttg ggtggagtta
    19561 gagatgaagc agaaataaga ggtcatagaa gaacttatgt aggttcaatt ccaggaagaa
    19621 taattaatgg ggtaaaagaa gcccaaacaa aaaatcctgt attcttattt gatgagatag
    19681 ataagatggc agcagattat aaaggtgacc cagcttcagc aatgctagaa gtattagacc
    19741 cagagcaaaa taaggatttt gtggaccatt acttagaaat accttttgat ttgtcaaaaa
    19801 tactatttgt tacaacagca aatagtctaa gtaatatacc aagaccatta ttagatagaa
    19861 tggaagtaat agaagtatct ggatatatag aagaagaaaa attaaatata gcaaaaaaat
    19921 acctacttcc aaaacaaatt aaagaacatg ctttaaaaga aaactttata aaaatagatg
    19981 atgaaacttt aagaagtata atcaaccatt atacaagaga agctggtgta agaacactag
    20041 aaagaactat tggtaagatt tgtagaaagg ttgccaaaaa atacgttgaa gacccaactc
    20101 ttgaagaggt tgttataaat aagtctgacc tagagacata tcttggaaaa gacatgttta
    20161 agtatcaact tgcagaagtt aaccctcaaa taggattagt aaatggtctt gcatggacag
    20221 aagttggtgg agttacactt gaagtagaag taaacgtact taaaggtaaa ggagaaattg
    20281 tattaactgg aaaattagga gatgttatga aggaatctgc gaagacaggt atctcttata
    20341 taaggtcaat agtggacaag tttgatatag accctgaatt ttataagacg aatgatattc
    20401 atatacacat tccagaaggt gctgttccaa aagatggacc atcagctggt ataactatgg
    20461 ctcttgcagt aatctcagca cttactaaaa gacctgtgcc tggaaatata gcaatgacag
    20521 gagagataac tttaagaggt agagtcttag cagtaggagg agttaaagaa aagttattag
    20581 cagctcatag agctggtata acaaaagtat taattcctaa agaatgtgaa gctgatttag
    20641 atgaaatacc agaaaatgta aaagaaaaaa tggagtttgt gcttgtagaa catatggatg
    20701 aagtattaga acaagcttta ttaaagagtg gtgaaaataa tgaaaattag aagttcagag
    20761 ataactatga gtgctgtgaa taaatcacag tatccagcag aaggaatccc agagatagca
    20821 ttggctggta ggtcaaatgt tggaaaatca tcaataataa atacattgct taacagaaga
    20881 aacttcgcta gaaccagtca aacaccagga aaaactagaa ctataaattt ttatctaata
    20941 aataatgaat tttattttgt agaccttcca ggctatggat atgcaaagat agctaagtct
    21001 gaaaaagaaa agtggggagg tataatggaa cgatatctag aaagtagaca agagttatgt
    21061 tctatattcc tacttgtaga tattagacat gagcctacag cagatgataa gcttatgtat
    21121 gaatggataa agcactttgg atataactgt gtagttattg caactaaggc agataaaata
    21181 tctagaggac aatatcaaaa acacataagt ataataagaa aaaaattgca aatggaaagt
    21241 agtgaaaaag taattcctgt ttcttcacta aaaaagactg gtgttgaaga attatgggaa
    21301 gagattgtaa atcaatacaa tcaacatgga tatgaaataa cagtagatta aatttaaaat
    21361 gttaaatatt gacatgagat ttatttgaat aataaatgta ataatagtta gttttaatta
    21421 tattaatatt aaagcaaaat ataggatgcc ttaaaatagt tttaatgaac tttttttggc
    21481 atccttattg tttataaaca ataaatatca gtaattttgt taaatactaa taaattttag
    21541 taaggtatgg gaaaattagt ataaattagt tcaactaaaa aattattgac ttatgtagtc
    21601 agcaataaat agcatttaag aaatagattt atctgttttt ctcataaaga aaacagttag
    21661 tataagccct ataaaacata ctgatgctgc aatccaataa gactgattgc tagctataac
    21721 ataggctgat gtgtgacttt taaacttttg attgtatgta agactttgtg caaaaaaact
    21781 actaaaaaat gctgttccaa gagcaaatga taaattacga atagttgcaa gaaaactgcc
    21841 tccgtatccc tgtttttgag gaggaacatc tgctaaaata ctactattgt ttggtgaact
    21901 aaatgctcct agcccaagtc caaaaataac taaacataca attaaaagat acaatggaga
    21961 atctgctttt aaaagtgcca ttccaactag tgagatggtc ataaatgaaa aagatgctgt
    22021 tagaatgttt tttgcaccgt gtttatcaga aagtgaacct gcaataggtg ctataagtac
    22081 cataataagt ggatgtacag tcattacata accagccatc ataggagata aattttttaa
    22141 ttgttctaaa taaaatggaa gtagaaaaga tactgccatt tgaggaaaat aacaagctac
    22201 tccaatgata ttgcctacag taaagtttct atttttaaat agaggtaggt caataaagct
    22261 ttgttcaaat tttacttctc ttaatgccaa caataagaag attataagtg ctgttatacc
    22321 taaatacaat cttgtattac ccttctcatt cattgcaagt aatataagcg tagtgcaaga
    22381 tgcgaaaagt agaagacctg gaatatcaaa gctcttgttt tgttcatcca aaacaggttt
    22441 aggtagaaat ttaatgccaa gaaagactgc tataatacca ataggtatat tgataataaa
    22501 aatagaaggc catccaaaat gttctaaaat tatacctcca attacaggac cactcatatt
    22561 tcctatacca actacagctc cagtgattcc tatagctttt cctttttcat ttgctggaaa
    22621 tgcattggaa actataccaa gcccagtagc cattaaaata cttgctccaa ctgcctgaaa
    22681 gattcttgaa gaaattaatg ttgataaatt gtttgacata ctacacagaa aagaacctat
    22741 tgtaaatata aaaaatccta atgtgtatag acgatttgaa cctactttat cgccaagttt
    22801 tccgaaaaat aacatagtag ctgttacaac aagcatataa gctgttacaa cccactgaat
    22861 ttgtgacatg ttaattttaa agtcagcagc aattgtagga tttgcgatat ttagtatact
    22921 tccatcaaga gtagacataa atacaccaat acagatgata atcaatacta tccatttttg
    22981 tttcatgata acactccaat cttaatagat tttataagta cgatataatt gtaaaataaa
    23041 caacaaaaaa agcacctgta tattaggtac cttgaatgtg tctaatttca tgaataaata
    23101 cggtagttga aggatttgta tagattactc atgtaaaatt acataaaggt actcatatac
    23161 tattttcttc taccatccag attttactgt cggctttgga atatgaccaa attatgccat
    23221 aaggctcgcg ggcttttacc gccgataggg aatttcaccc gtttatgaag aaaaacagat
    23281 gtattttgta atattatttt aacataaaat tataatggaa acaattggat ttaagtaata
    23341 tccagctgta ttacaataca aatatttcaa tatggacact taaattgtat ttatagatag
    23401 aataaggaac agtatgagaa tctataataa ttagataaaa ttaacctgtt attagtatta
    23461 gatggtaagt tttaaattta tcaaaatcag aaagctgtaa taaaattctt ataatatgaa
    23521 tatcttaatt aagagatatt gtaaattatg aggaggcgct aatatggaag gaaaggtaaa
    23581 gaaggcattc ccgggtggaa atacatcaca aggctcatat tctttttttg actatataat
    23641 tcctgaaaat gtaaaaagag ttttttgttt aaagggtgga cctggagtag gaaaatcctc
    23701 acttatgaaa aaaatttata aagagttttt gcatagagga tatgatattg atttatatca
    23761 ttgtccttct gacccaagtt cgttggatgg tttagttata aagaaattag gcgtggtact
    23821 tatggatgca actgccccac atactatgga cccaaagcta cctggagctt tggatgagat
    23881 aattaattta ggtgattact ggaatacaga agaattagaa aagaataaac aagaaatatc
    23941 agtttatgat aaagatatta gtaattcatt taaaagagca tttaagtttt taaaatcagc
    24001 agaaccaatc tttagagaca tagaagaaaa atattctgat tgtatggatt atggaaaagt
    24061 aaatttggtc acagaagaat ttataaaaag gttatttgat ggagttaaaa gcacaggaaa
    24121 tctaaaaaga gaaaagcatt tatttggttc agctataact cctgtagggt gtttagatta
    24181 tacagaaaac attttaaaag atgtaaagaa agtctattat ttagatggag aaataggaac
    24241 tgggaaaact acattattaa acaaagtata taagaaagct attgaaaaag gtttaaatgt
    24301 agaagtttat cattatccac ttattccaga gaaaattgaa actgtactat taactgattt
    24361 agatataggc ataactataa gtacgacttt taaagaagaa gatacaattg atttaaatca
    24421 gtttttaaat agagaaaaac tacttaaata tgaagaagat attaaatttg atgaaaaagt
    24481 tttagatgat ttaatttgtt gggcagtact aaatcttaag agagccaagt ctaaacatga
    24541 tattatagaa agttactata gtcctaatat gagatttgat gaagtaggga aattaagaga
    24601 taagttaatt aaaagaattt taaaatatga ggaaaactta taaacgcata tgtttaaaat
    24661 taacgttagt aataatataa tttttagtaa attggtgtag ctttgaggct atgccatttt
    24721 actttttttg ctaaaaaatg atattaataa tctccaaagc cattatttgt ttttcataat
    24781 tattatttcc tttcctaatt tatgtttttt tataatatca caacaatgtt tattgaaagt
    24841 ttatataatt ttaagaacat ctaaaaatgc atacttgata ttggtaaatt agtgatagga
    24901 gttcaatgta tgatattata tactaaagat gaattttaat atataacttt gatataataa
    24961 gcatatgtaa atgtttaata tttaattaaa gaaaattatc atataaaaat aaatttgtaa
    25021 ggagcaatac agtatgaaaa aacaatatgt gtttataata ctagcaagta ctattttagg
    25081 tatacttgtt ggaaccatat ttagagatta tagcaatgaa gaaacagttt atacaagcaa
    25141 agacaagtca ataagaaaag aaataaaaat gacaagaaaa tctataaaag aattaaccaa
    25201 agagaaagac aagttagata aagaaattaa ttcaatgaaa caaaatcaaa aaaattctga
    25261 agaaatatca gaaatagaaa cacttagaga tagtctatca tattcagatg taaagggtag
    25321 tgggataata ttaagtatag atgctataga tgaaaaaaca gggaatatag ctaatagtat
    25381 agactataat aagattcttg taaaagttat aaatgaatta aaagtaaacg gaggaaaata
    25441 catagaaata aatggtcaaa gaattaatca atattcagaa gttgtacttg caggaagcca
    25501 tataaatata aatggagttc ctgtagcaca accatatgaa ataaagtgca ttggagataa
    25561 ggagaaacta tctaattatg tagataaagg tagtaaatat ttagatagca tacaaaccaa
    25621 ttatccaatg aaaataagca taaaaactga agaaaatatc tctatgaaaa aaatgaatat
    25681 acctaataaa ttaaagtata taaagggtga ttaagattat attagaggaa agcagtttgc
    25741 caatgttaat accagaaaaa cttgcaaaaa aatataatgt atttccagtt gagtttcaag
    25801 atgataattt agttgtagaa atagaagatg aggatattta tgctctacag gacttgagat
    25861 tagctacagg taaagaaatt atattgaaga aggagaaaaa agaacttata agtgaaaaga
    25921 ttgaaaaata ttataatagc tttgaacttg atgaggatta tgcaaaaaaa ttatttgaaa
    25981 atcttttaga aaaagctata aaagaaaacg caagtgatat acatatagaa ccatttaaag
    26041 aacatttaat agtgagaatg agggtagatg gagaactaaa ggaagtatca aagtttttag
    26101 ttgatgtcta tccatcattg tctacggtta taaaattaaa ggcatcaatg gatataacag
    26161 aaaaaaggct tcctcaggat ggtagggtgg atataaagtt aggtggaaat ttaattgaca
    26221 ttagagtttc atcaatacca actgtctatg gtgaaaaaat agttttgagg atacttaata
    26281 gagatacttt tttaaaagac aaattagaac ttggtttttc agaggaagct ataaaatcta
    26341 taaatcgtat aataaataaa agagcaggaa tattattagt gacaggtcct acaggtagtg
    26401 gaaagactac aacagtatat tccttattaa atgatttaaa aggaataaat aaaaatatta
    26461 tgactataga aaatcctgta gagtataaga tggatggcat aagtcagatt caagtaaatt
    26521 caaaagtagg gttgagcttt gatgtaggtc ttagagcgat attaagacaa gacccagata
    26581 taataatggt cggagaaata agagatgcag aaacagctaa gatagcagta agagcagcta
    26641 taacaggtca tttagttata agtactttac atactaatga tgcagtatct tccatagcta
    26701 gattactaga aatgcaaata ccaccatatc ttttaaatgc ctctcttata ggtgttatat
    26761 ctcaaaagtt ggttagaaaa gtctgcaatc attgtagcca tgagattatg ataaaagata
    26821 attttagtgg agatgtaaat actaaggtag ctgtagggtg tgaaaaatgt aatgataaag
    26881 gatactttgg aagaacagca atttatgaaa tcttagaaat taatgatgat ataaagacat
    26941 gtataagaaa tatggaggat tctagtacta ttaaagatgt agcacaaaat aatggaatga
    27001 taacatttga agatagttgt aaaagactaa taaatgaaaa aataacgaca ttagaagagt
    27061 gtttagtagt aaatgaaatg atttaactga attgtatagt taaacttcgt ttggtcagtt
    27121 gtctttattt aatctatttt aattaagatg tttgagtata aattatattt aagtgaaata
    27181 aaattaaatg cattaaatta gaaaatatta agtttattta attgtaatta atataatttg
    27241 gaaggtatta tagtacatga gattatctaa aaatatattt tataatttag aaaagtttta
    27301 tttagtatta aatagaatca gtgataaaga aattagagta atttgcaaag agataggcat
    27361 attgctggaa tctggatgtg aaattacaaa aatatttgaa atcattgaga gtcagtcaag
    27421 taaaaaagta aagaacttgc ttagtatagt atcaaatcat attcaaaaag gtaactcaat
    27481 agcagaatca tttcaaataa caggtatatt ttctaaattc tttataagta tgataaaagc
    27541 aggagaaact agtggaaact tagatataat aatgagtgat ttatctaatt attatgataa
    27601 agaatacaaa ttaaaaatga aaataataac tatttcaata tatccaataa tacttataat
    27661 attatctatc ttatcaatgt tgtttatatt cgtatttgta atacctaatt ttcaggtggt
    27721 ttttaccaac aatggaattg aaccaccttt aataactaga gttttaatgg gaatatctac
    27781 agtggttaca aataacttag cttatataat atttagtttt atattgtttt caataggaag
    27841 catttatttc tttataacaa atgataatat aaaaaaattg attaattcgt taaaattcaa
    27901 aatacctttt ataaaaaaaa ttaatcagtt agtagctaca acaagatttt caagggcatt
    27961 gtccgtttta attagcagtg gaatacaaat tgtggaagct atagatatgt cagctagtgt
    28021 tatagacaac gaatttattt atgaaaggtt aaagatttct aataattata taaaaaaagg
    28081 aaatagcata ggtaaatctt tgaatttagc aaatattttt ccaaaattat ttatttcaat
    28141 ggcaaataca ggagaagaaa gtgggaaact agataaaagt ctaaatgtaa taaataaatt
    28201 ttatgaaaat gaattaaata acaaaataga gcaaataatg aaatttatag aacctatgct
    28261 aattgtattt atgggattaa ttattggtac ttttatttta gcaatggttg ttcctatgtt
    28321 tgatgcaatt actaattttt agagagaaaa ataaatttta ttagatgaaa cttttgaaaa
    28381 ggagagaata tttaattgat aaatttgata aataaaaaac gaaaaggatt tacacttgtt
    28441 gaaatgattg tagtagtaac tattttaggc gttatatcta gtatagcatt agttaagtat
    28501 agtaaggttc aagaaagtgc caaattaaat gcagactata cgaatgctgc taatatagta
    28561 accgcagcta gcatggcaat taatgatgat gaaaagacaa tagactctct aagtgtagag
    28621 acattgaagg aaaagggata cctaaatact gttccagttc ctcagagtac atcaggtaaa
    28681 ttcgaacttg tcataaatga tagcggaaca gatataagcg taaatataaa ttctaagcaa
    28741 ttttatccaa aataatattt tatattgatt gctgtaagtt ttaaaattat ttttatttaa
    28801 gaaggagatg gctataatta aaaaaattct aaacttagaa ataaatgatg attatataag
    28861 gcttgtattt ttaagaaaaa gtcataaaaa agtttttata gataaatcaa ttataaaaga
    28921 gattaacttt gatataaaaa atgatagtaa ttcgattgag aagattaaat atatagaaga
    28981 tgtagttaga tttgtaaaag aggagattgg taaatcaaaa atattatata aaaatttata
    29041 ctttaacatt caaattcagg atatagtcat tagaaatgtt gaagttctaa atactaagaa
    29101 aaaaagagac atattaagca tgattgaatt tgaaataaca caatacattc caataaacat
    29161 aaataactat tcaataaaat ataaagttat aaattctaaa aatgataaat tgaatataca
    29221 agtaattctt ttcccaaaga atattattca attaattaag aacatttcag aaaatctaaa
    29281 tatgaatcca aagactataa atataaattt tgatatatta caaaagctta taaacttaaa
    29341 tttaatagag aatttttcag aagaaggggt atttatagaa tgtaaaaaaa gtcagttaat
    29401 tataaatata acaaaagata aaaaaataag agaaacatac ttgctatcaa aagagggaaa
    29461 atcatatgag ttcataaaaa gattattaag gggttttaag tatgtttatt actatggtat
    29521 agaaaattgt tttattgaag aatactttaa atatacagat aaatctattg aagtaaatcc
    29581 attaagatta aaagataaag taaaagtaga aaataatttt gatgcagatt tagaagacaa
    29641 taggataaat tatataaata gtataggaat gattatttaa gtgaaagtgg ataaaacaat
    29701 aaattttctt aatggattta aaaaaactaa accatgtaat aaaatctata aaataataat
    29761 agtcttaatt ttaacgtgta ttttatttaa atcatttatg tatgtgaaat ctataaatga
    29821 acttgaagat tatataagtc aaaataagct agtggataaa tcaaagaaca ctttaccaac
    29881 aacagataaa actagagaga aattttctaa aataaaactt aatgaaataa aaaaaatata
    29941 tgaaacaatt ggaataaata gtattactaa aatatcaata gataaaaata agctagagat
    30001 ggaaggtgtg tgtagtgatt tagatgtttt aaacaattta aggaaaataa agtacataaa
    30061 atattattac atagacagta ttgtaagaga tggagaatat tatagattta gaataaaaag
    30121 ttagatgggt gattattttt gagattaaat aatagagaaa aaaatctact taaaatattg
    30181 ttaatattag ttattatatt ggcaagtgat atagcagtaa gttatttgga agaaaaccta
    30241 actagtttga agaatgaaaa gcaaaatata ataaataaaa taaataatca agataattat
    30301 caaataaagg ataataagca tatagatgat aaatatatag aaagtgttga attaaataaa
    30361 aatgaagaat tgaaaaataa ttttaataac tcatttttag ataaaaaaac aaataaagat
    30421 atagtgttat tagtagaaaa tgaactgaga gatattgtga atgtagaata tattaatcaa
    30481 gaaagtagtt tagataatca caataaaaaa caagttaatt tagaaataaa agttaatgga
    30541 gaacttgcaa atgtgttgaa acttgaaggt gtaatgaaga agttaagact aaataataaa
    30601 cttgaaaaga tagaaattaa caaattaaaa gtcaataatt ttgatgttca aaatattcca
    30661 aatgaatata aacaagaaaa agacaatatt gttgaatgta aaatgacagt tagagtcata
    30721 taacaaaaaa gaatagataa agtaaaaaac tattatcaat taataaaatt ttatagagga
    30781 attagtttta cgataattca tttctacaag agggattgtt gatgatttta tcgaaatcct
    30841 aattaaagtt aatatattgt accaaaatat aagtgaattt aatagaatat ttacttatac
    30901 tatagattga ttaataaaaa aatggtataa taacaaattg tactttaatt taataataag
    30961 ggagtggaag tcatattgtt agggagaaat gagctatgcc cttgtggaag tggcaaaaaa
    31021 tacaagaaat gttgtttaaa taaagatatt gtttcagaaa gagcatgcag aaaaactgaa
    31081 ctttcacaaa aacaatatac agatttatat tcaaagttat atgattattc aagacaggat
    31141 aagtttaaag aagaatgtga aaaagctaaa gaaatgtttt atataatgca aaatgatagt
    31201 gtaaatgaaa aatttgaaag attttttaat acttatttaa tacaagacca cataatggaa
    31261 aataaaaagg ttatgacagt tggttttctt gaagaaaatg gtgcaaacct aagtcaatca
    31321 gaagtatcaa tattaaaaag tatgtttgaa tcatacgtaa gtatttatga ggtaaaagaa
    31381 gtttctgctg gaaaaatagt attaaaggac tgtttaaatg gaaatgaact ttgtacagaa
    31441 gatgtaaaac ttctgagaag ttttaaaatc ggaagttgta tgatagctag aatagttgat
    31501 attgaaggaa ctaacatatt gatagatata actataagta tatcaaatga ggttaaagat
    31561 ataattttaa aggatattat gaatctattc aatcaatatc aagatgtata caaagatatg
    31621 aagtcgttct taatttatca tacacatata ctatacaagt atatacaaca gcttttagac
    31681 ccaagtatag ctgaatattt aaagagagaa agagataaaa acgatacaaa agttaattca
    31741 gaaaatgaat tagctgaaga agaatgtaaa gttttagata ctcttaaaga aaatgtagaa
    31801 aaagaaaata tagatgcatg tatagagttt tggaatgaat ataagaaaaa tcatgaaaat
    31861 ataaaaggag ctgaaaatgg ttgggcagct gctgttgaat actatgttaa aaaagaagca
    31921 ggacaaccta taactcaagt tcaaatatca aagaaatacg atataagctc tagtacacta
    31981 ggaaagagat acaaggattt aaaaatatct taattaatta taaaaagctt taagtcatag
    32041 ataaagaatc tatagtataa tatatgtata atgtttagaa agaggtatta ataatgagtc
    32101 ttagtttagg aaatgcaatt gctgtatcaa cgaactttat aaaatctaac ccagctgtac
    32161 ctgtgtacaa cggagaagaa atatatgcag ttatttatca tatagaaata ggatataata
    32221 atggtgtatc acctgatacc aaacaatata taataataga ctataaagag tttgatttat
    32281 ctatggataa aaaaaatgaa ctaataaata ttgctaaaga gtactgtaaa tctaaaggta
    32341 ttgtagaaaa cgaaaacctt gaaataaacc ttttagacaa tgaagaagca gagaacttct
    32401 tagaaaaggt gtttaataat atgaaggtta taagaggtct tataactaaa aaaggataaa
    32461 taaatggact atataggaat agaaaatata acaccttatg aaaatacata tgaatttagt
    32521 gtatatgaat atgatgatga aatcacctta ggtagtgaaa agttatatgt atgtgaatta
    32581 agggttgtat tgattaaagt taattctctg tatgttgaaa gattgcataa atcagttgaa
    32641 gcaatggtct tagtaaaaaa cttgaaaaaa gatttagata aaacacttgt tgtaaacaaa
    32701 ataaagaatt ttgtgctaga tgagatttgg gtagaaaatc tagtaaaaga gaatatagaa
    32761 gttatatttg tagaaagcta ggaataaccc tagctttttt atattacaat ctaagagagg
    32821 aaaacaatat gttaagagta tctaatgtaa aacttggaat tgataaagat atatctttat
    32881 taaaagatgt tatacttaag aagctaaaaa taaaagaaaa aaacttagtc aaatatagta
    32941 tatataaaga atctatagat gctagaaaaa aaggaaaaat ggaatttgtt tattctgtag
    33001 atgtagaagt taaagatgaa aataaaatac ttaactcaaa aataaaagat gtaacaaaaa
    33061 taaaggaaat cagatacgta aatgtacctg tgggtgataa aaaattaaag aataatcctt
    33121 tggtaattgg tagtggacca gctggcttgt ttgcaggtct gcttttagct caaatgggtt
    33181 atgaaccaat catacttgaa agaggtcttg atgtagacag tagaaccaaa gatataagtg
    33241 atttttggac aactagaaaa ttaaaaaata attcaaacgt tcaatttgga gaaggtggag
    33301 caggaacttt ttcggatggt aaacttacaa ctagaataaa agatatacga tgtagaaaag
    33361 tattagaaga gttagttcag tttggagcac cagatgaaat attatactca cataagccac
    33421 atgttggaac agatatatta aaaaatgtag ttaaaaatat aagaaatgaa ataataagtt
    33481 taggtggtca agttagattt aattcaaaag taacagatat agttgtatca aatgattcta
    33541 tacaatctgt aataataaat gatactgaaa aaatagatac agatacaatt atattagctg
    33601 ttggacatag tgcaagagat acttatgaaa tgttgtattc aagaggtata aaaatagttc
    33661 aaaaaccttt tgcaatagga gctagagttg aacatccaca agatttaata aataaagcac
    33721 agtacaagga tttttataat catcctaggt taggagctgc agattataga cttatagagc
    33781 atgtttcaaa tggaagaaca gcatatactt tttgtatgtg tccaggaggt agtgtcatag
    33841 catctgcatc aaatgatttt gaaatagtta caaatggtat gagtgaacat gcaagagata
    33901 aaataaatgc aaatagtgca tttttagtaa atgtaacgcc agaagatttt aagagtgata
    33961 atccactagc aggtgttcat ttccagcaga agtatgaaaa attagctttt gaattaggtg
    34021 gaaaaaatta taatgcacca gttcagcttg ttggagattt tataaacaat aagacttctt
    34081 tgaatttagg aagtgttgag ccatcatata gaccaggata tacacttaca aatttaagtg
    34141 aatgtttgcc tagcttcgta acagagacta tgagagaagc gtttatatct cttgataaaa
    34201 aattgaatgg gtttgcaatg tatgatgctg ctttgacggg agtagaaact aggtcatcat
    34261 caccaataag aatagtaaga gatgaaaata ctttagaatc agtgagtatt aagaatctat
    34321 atccatgtgg tgaaggtgct ggatatgcag gtggtatagt tacagcagca gttgatggta
    34381 taaaatgtgc agaaaaaata atacaaaaat acaccaataa tacaaaaatt taacataaac
    34441 ttaatgattt tttaatattt aacatgaatt taacattatc actcctataa tttgataaaa
    34501 tacaataggt tataaaattt ttagatacag taatctcttt acaaggagga aataatttga
    34561 acattataat aagtctaatg ggtggattag gtctgttctt atatggtatg aaccttatgg
    34621 gagaaggtct tcaaaaatct gctgggacaa agctaaaaaa gataataaaa ctacttacta
    34681 gtaacctatt tatgggagtt ttggtaggta caggagttac agcagtaata caaagttcaa
    34741 gtgctactac tgtaatggtt gttggtttcg taaatgcagg aataatgact ttaaaacagg
    34801 caataggagt tataatgggt gctaatatag ggactactgt tacagcccaa ttggtatctt
    34861 tcgacttaac tggtatggcc ccagtagcat taggtgtagg tattatactt tatttatttg
    34921 gaaataagcc tagaataaaa aatatagccg aaatacttat aggttttggt atattattta
    34981 caggtatgga ttttatgaag atggcagtgg agccactaag agactatcaa ggatttactg
    35041 acttacttgt tacatttggt agatatccac tacttggatt attattggga tttgggatta
    35101 cagcaataat acaaagttca agtgcatcta tgggtatgtt ggttgcactg gcagcagaag
    35161 gtctagtgcc attatcagca gcactgccaa ttctttatgg ccaaaatatt ggtacatgtg
    35221 taacttcact gttatcaagt attggtgcta acaaaaatgc acgaagagca gctatgatgc
    35281 atctaatctt caatgtttta ggaacggtga tattcttaat attcttgaat aaaccagtag
    35341 taagcatggt tacaagttgg gacccaagca atgttgcaag acaaatagcc aatacacata
    35401 cattgtttaa tataatatct gtattgatac ttttaccatt tacaaatctt attataaaac
    35461 tagctataaa gcttgttcct gatagagcag gtgatataga tgaagatgaa actaaaacta
    35521 ttaaatatat agatgataga atgatagaaa ctccttctat agctcttgca aatacgataa
    35581 aagaagcact tcgtatgggt gagaaggcga aggaaagcct aaatgcatct atggaagctt
    35641 tagtagaaca ttcaactgaa aaaatagata agacatatag gcgagagaga ttaatcaatg
    35701 atttacagaa agctatttta aattatttac ttaaactttc aaaagcacct ttagatgatg
    35761 attcaagaga agttgtggat actttgttta atacagtcaa tgatatagaa agaattggtg
    35821 accacgctaa aaatatagct gaattatcgc aagttgcaat agattcaaat atttctttct
    35881 cagaagaagg acaatctgaa cttgatgtta tgtataatag agttgtttca gcatatactt
    35941 atgcattaga atcaatgaga actgataatg ttgatttagc ttgtaaggtt ataaaaattg
    36001 aagaacaagt tgatataatg gagaaatctt gtagagctaa tcacatgtat agattgaaca
    36061 ataatctatg tagtatagaa aatggagtta tttatttaga cgtaataagt aatttagaga
    36121 gaatatctga ccatgctgtc aatatagcac aacaagttat agcaaagaga ttaggaaatg
    36181 attaaaaata attaatttaa aataatataa aatttaaaat agaggataaa taaaagagaa
    36241 actttaaatg atacgtttag agtttctttt tttgtaaatt tatttgacta aaatttttaa
    36301 atttatacat agttatagca tttagaagaa tcgatttcct gataataaat gatgagatat
    36361 gtatgatttt gtggcaaact tttaaaaaaa acacctatat tttgtgttat aatctcttta
    36421 aaacgaatat gctgaaaaga gggatttaaa tgggaaaaat aaattttgat tatagtaaag
    36481 ctacagagtt tttttgtcaa aacgaaatag atgtcatgca accatatgta gatgttgcgc
    36541 acgacatgtt acataataaa actggtttag gaaatacttt tttaggatgg atagaccttc
    36601 ctaaaaatta tgataaagaa gagtttgaca gaataaaaaa atctgctgat aagataaaat
    36661 cagactcaga tgttcttttg gtaataggta taggaggctc ttatttaggt tcgagagctg
    36721 ctatagatat ggtaagtcat tcttttagga atggacttaa aaaagagcaa agaaaggctc
    36781 cagaagtata ttttgtaggg cataatataa gctcaacata tattatggat ttattagata
    36841 taattgaagg aaaggatatt tctgtaaatg taatatctaa atcaggaact actacagaac
    36901 cagctctggc ttttagaata tttaaagatt acttagagaa aaagtatggt aaggaagaag
    36961 caagaaagag aatttatgca acaacagatg caagtaaagg tgcacttaga cagttagcta
    37021 cagaagaagg atatgagact tttgtaatac cagatgatgt aggtggtcgt ttttctgtat
    37081 tgacagcagt tgggttactt cctattgctg ctgctggact tgatattgat gctatgatga
    37141 aaggcgcaaa tgatgctaga gaagcatttc aaaatcctga cttaaaaagt aatgatagtt
    37201 atagatatgc tgttgctaga acaattttac atagaaaagg aaaagatgta gagttattag
    37261 tgaactatga acctcaacta cattatgtaa gtgagtggtg gaaacagctt tatggagaaa
    37321 gtgaaggaaa agaaaataaa ggtttattcc ctgcttctgt agatttctca acagatttac
    37381 attctatggg tcaatacata caagatggaa aaaggctttt atttgagaca gtacttaatg
    37441 ttgaaaactg taagagaaat ataactataa gttcagagga agtagactta gatggtttaa
    37501 actatttagc aggtaagact gtagattttg taaatcataa agcttttgaa ggaactctat
    37561 tggctcatac agatggaaaa gtacctaatt tagtaataaa tatacctcaa ctagatgagt
    37621 ataattttgg atatttagtt tatttctttg agaaggcttg tggaataagt ggatatttat
    37681 tgggagttaa tccatttgac caaccaggag tagaagctta caagaaaaat atgtttgctt
    37741 tactaggcaa accaggttat gaaaaagaaa aggaagagct agaaaaaaga cttaaataat
    37801 tttaaatagt taaggtttaa ttaagattaa aataatataa tgaaatcatc gaaaaggagt
    37861 ttactcaaaa tagatgattt catttttttt atgaaaaatt gggaaaaata tattttgata
    37921 atttatatta tattaagata gggagtggta tgagatgtca agaagaaaga aagggataag
    37981 tttagtaata ttagttgcta taataagttc aatacttagt agttttctaa caataatttt
    38041 agttaaggac aatttagtaa gtaaatctac aggaagttct acgccgatag ttgtaaatga
    38101 tgatggtaag agtcaaaata tttatcaagc agttgcagaa aaagctacgc catctgttgt
    38161 aggtattaca acaactagtg ttgatactag taatatgttt gcaataccaa ctgaaacaca
    38221 aggtgtagga actggaatca tagttgattc aaatggatat atacttacta attctcatgt
    38281 tatatcagat ggtcaagcta caagtgtaaa tgtattattc aatgatggtt caacaacttc
    38341 aggtaaagta gtatggtttg accaacaact tgatttagct atagttaagg ttgataaaac
    38401 tggactaaca ccagcagaat ttgctgatag tgacaaagta aaagttggag atatatcaat
    38461 agcaataggt aatcctcttg gattagattt tcaaaaaaca gttactcaag ggataataag
    38521 tggattagat agaactatac aaacagaaaa aactaatatg actggtttat tacaaactga
    38581 tgcaagtata aatgcaggaa atagtggagg accattgtta aatcaaaaag gtcaagtaat
    38641 tggtataaac acagcaaaag cttctcaagc agaaggatta ggatttgcaa taccaatcaa
    38701 tacagctaag agtatagttg aagaagtaat caaaaatgga aaatatgaaa aagtaacttt
    38761 aggcataaaa ggtacagatg tatcaaatta tgaagcagca acaggtacaa aattaagtac
    38821 tgataaaggt gtttatgttg cagaagtaat atctggttca tcagcagaaa aagctggagt
    38881 aaaggtaggg gatattataa ctaaagtagg agatacagat ataacaggta tgaatgattt
    38941 aaataaaaag ttgtatactt tctcaaaagg tgctagtaca aaaataacag taaatagagg
    39001 cggaaaagca gtaacaataa atgtgaattt ctaaatatga ccagaaagat agagactaca
    39061 tggtaaagtg tagtctctat ttttatttaa tttttatagt atatacatct aaattaatta
    39121 aaatgatgta ttgtttatag tttattgcta tattttctta taaaaataaa tttaataaat
    39181 atttaaattt aatttacaaa aacaatataa atatcataat aaaataaaat tttttaatat
    39241 tactaaaaat atatagacaa aataataacg aatatagtat tatgtaattg tagaaatgct
    39301 tttcataggt atattctatg aagatgaatt gcataaaaat gaaaaaatgg aatggatatt
    39361 atttaggggt gaaaaatcat gaatccatta gttataaact tacaaaaatg tagcatacat
    39421 gatggaccag ggataagaag tacagtattt tttaaagggt gtccacttga atgtgtttgg
    39481 tgtcataatc cagagagtca aacatataca aaacaagttt tgtataatga agaaagatgt
    39541 tcaaaatgtg aagcatgtat aaatatatgc cctcataagg caatttacaa aggtgaaaca
    39601 aaaatatgct tagaccaaga taagtgtgag ttttgtgaaa cttgcttaga ctattgtgta
    39661 aacaatgcaa gagagattgt tggtcaagag tattctgtaa gagatttggt taaagagata
    39721 gagaaggata gaattttcta tgaagaatca ggtggtggag taactctatc aggtggagaa
    39781 gtaatggctc aagatatgga cttcatttgt ggagtaataa acatgtgcaa atcaaaggga
    39841 atccatgtag caattgatac atgtggctat gcaaagtcag aaaattatga aagagttgct
    39901 aaatgtgcag atttgttttt atatgatatt aagcttattg atgaagataa gcacataaaa
    39961 tttacaggaa aatcaaatga cttaatactg aaaaatgtta agattttaag tgaattaggg
    40021 gctaacataa atataagaat accattaatt gtaggagtaa atgtagatga tgaaaattta
    40081 gaggttaaaa aaatgataga gtttttaaag cctttgaata tacaagcagt aagtcttctt
    40141 ccatatcata atattggtaa acacaagtat gataaaattt ataaaaagta tgaaggagaa
    40201 gaactacaaa gaccatcaga agaaaaatta gaggaaataa aaagactgtt tgaagcaagt
    40261 aatttcaata ctaagattgg agggtaataa aatggcaaga ggaacttttg agagaactaa
    40321 aaaattaaga gaagaaagta ttaatgcaga accacacata tctattgaaa gagcagtact
    40381 tatgacagaa gcttataaaa aatatgaggg aagtgtagag attcctgtac ttcgtgcttt
    40441 atcatttaag cattatattg agaatagaac tcttagcata aatgatggag aattaatagt
    40501 aggtgaaaaa ggtgattctc ctaatggagc accaacatat ccagaaattt gttgtcatac
    40561 aatggaagat ttagaagtaa tgcacaatag agatataata aattttagcg tatcagaaga
    40621 agctagaaaa atacataaag aagaaataat tcctttttgg aaaaagagac aaacaagaga
    40681 taagataata aatgcaatga cacctgagtg gttagcagca tatgaagcag gtatgtttac
    40741 agagtttatg gaacaaagag ctccaggaca tacagtttgt ggagatacaa tatataaaaa
    40801 aggattttta gatttaaaga aagacataga agcaagatta aaagagctag attttcttaa
    40861 tgatttagat gcatataata aaaaagcaga tttagaagct atggcaatag cttgtgatgc
    40921 aatggttata ttaggtaaaa gatatgctga gaaagcaaga caaatggcag aagaagaaac
    40981 agatgaagct aagaaaaaag atttattact aattgctgaa acttgtgatg ttgtaccagc
    41041 tcacaaacca gaaacttatc atcaagctat acaaatgtat tggtttgttc atataggggt
    41101 tactactgaa cttaatatat gggatgcttt tactccagga agacttgacc aacatctaaa
    41161 tcctttctat gaaagagatg tagaaaatgg aatactagat agagatagag cacaagaatt
    41221 acttgaatgt ttatgggtta aatttaacaa tcagccagca ccaccaaaag ttggtataac
    41281 attaaaagaa agtagcacat atacagattt tgcaaatata aacactggtg gaataaatcc
    41341 agatggtcaa gatggtgtta atgaagttag ttatataata cttgatgtta tggatgaaat
    41401 gaaattgata caacctagtt caaatgttca aataagtaaa aagactcctc aaaaattctt
    41461 aaagagagct tgtgaaatat caagaaaagg atggggtcaa ccagcatttt ataatactga
    41521 agcaatagtt caagagctta tggaagctgg aaaaactata gaagatgcaa gacttggtgg
    41581 aaccagtggt tgtgttgaaa ctggatgttt tggtaaagaa gcatatgttc taactggata
    41641 tatgaacatt ccaaaaatac ttgaattaac attaaataat ggatatgacc caattagtaa
    41701 aaaacaaata ggtattgaaa ctggagaccc tagaaatttc caatcttatg aggaactatt
    41761 tgaagcattt aaaaagcaat tacattatat gattgacata aaaatagaag gaaatgctgt
    41821 gatagaaaat atatgtgcaa aacacatgcc ttgtccactt atgtctacaa tagttgatga
    41881 ttgtatagaa aaaggcaagg attaccaaag aggtggagca agatacaaca ctagatatat
    41941 acaaggtgtt ggtataggaa ctataacaga tagtttaaca gcaataaaat ataatgtatt
    42001 tgataagaaa aaattcgata tggatacatt gcttaaagca cttgatgcta attttgaagg
    42061 atatgaagct atacttaatt tagtttcaaa taagactcct aaatatggaa atgatgatga
    42121 ttatgctgat gaaataatgc aagagatatt caatgcatat tacaatgagg taactggtag
    42181 accaactgtt tgtggtggag aatacagagt agatatgtta ccaacaactt gtcatatata
    42241 ctttggagaa attatgggag caagtccaaa tggtagactt tgtgcaaaac cagtttcaga
    42301 gggaatttca cctgaaaaag gtggagatac taatggacct acagcagtta taaaatcttg
    42361 tgctaagatg gaccacataa aaactggtgg aacattatta aatcaaagat ttgcaccatc
    42421 agtagttcaa ggagaaaaag ggttagataa tatggctaat ctagtaagag catactttaa
    42481 tatggatggt catcatatac aatttaatgt atttgataaa aatgtactgt tagaggctca
    42541 aaagaatcct caggattata aagacttaat agttagagtt gcaggatata gtgaccattt
    42601 caataattta agtagaacac tacaagatga gataatagga agaactgagc aaacattcta
    42661 ggtttgcttg taaataaaac ttcttactat ataaaatcgt aactgatata ataaagtata
    42721 aatggtttga ttccattttt aaaattttag attaattatg agctaacttt ctaaatagga
    42781 agttagctcg ttaagtttaa tgaaaaaatc gttaaattta tatttagtaa atcatacaca
    42841 tattagtaag taatacatac aaaagaataa tttattatag ttataataag gttatatttt
    42901 ataaaaataa gataatttta agcagttaaa ataaagtcaa tttagctact ttaaaataaa
    42961 actaatagaa aaaaggagat ttgatatgaa aactttagga tttattggtt cagggaatat
    43021 gggaagtgca atgataggtg gcatagtaca gtcaggatta gtaaaggcag aagatataac
    43081 tgtatcagat ttaagccaag ttgccttaga taaagtaaaa gaaaaatttg gagtaaatac
    43141 tacaactgat tcaaaggtag ctgttacaaa ttctgatgtg gtaatagtag cacttaaacc
    43201 taatatatgc gaaaaggctt taactccact taaagaatta atagatgcaa ataaaataat
    43261 agtatctata gcagcaggta aaactataga aagtctggaa agttttatag gttcagataa
    43321 aaaaatagta agagtaatgc ctaatactcc agcccttgtt ggcgaaggaa tgtcagctct
    43381 ttgtaaaaat agtaatgtaa cagatgaaga gttaaatatg attaaggctc tgtttgaatc
    43441 ttttggtgag gcagaaatag tatcagaata tttaatggat acagttacag gtattagtgg
    43501 ttcttctcct gcatatgtat ttatgtttat agaagctatg gcagatgcag cagtattagc
    43561 tggaatgcca agacaacaag cttataaatt tgcatctcaa gcagtaatgg ggtcagctaa
    43621 gatggttctt gaaactggaa aacatccagg tgaattaaaa gatatggttt gttctccagc
    43681 aggaactact atagaagctg ttaaggtatt agaagaagaa ggctttagag cagcagttat
    43741 aaaatctatt gttgcttgta tagataagtc taaagatatg agcaaataac agatgtaatt
    43801 aagtttacta tatggtttct tgaattgttt ttttagtgct tatttatatc tatacataaa
    43861 tgtatttggt ataagtaaaa taagagtaat ttactataaa aaggaattta atgattgagt
    43921 gataatttat tacttaaata ttaataatta aatagatata tttttaacta tatttgagat
    43981 atatcattgt gaaaaaataa aatttataag tattattgtg aggttataag tagatttatt
    44041 taaaaataaa tttatttata gcctttttaa atttgaaata atattcataa ggtaataaaa
    44101 gttacaaata ttttcttcgc taataagttt taaaatacct ataatgtttt actttttatt
    44161 ataataaata caataaatat attcttatat aaattctatg tcagatatat ggaaagataa
    44221 gaaccttgag attatgttaa aaaatctaga ttttatactt ataaaaagtt tgattttaca
    44281 aacttacaaa agagaatcaa gataggaata taattatctt tttcataaat atataaatga
    44341 tatactaata ttatagtatt attgatattt gtattggagg ttgaacatga gggatgaaat
    44401 tttaagtttt gtaaatgaat gtgtattatt taacaacttt gatgaactta aaaaagaaag
    44461 tggcataata acagaagata tagtaaaaaa gtttaattta agtagaactc aatcaagtag
    44521 attattaaat gatttagtaa aatctgataa tcttataaag ataaacagta gacctgttat
    44581 ttttttacct aaaaataaaa taaatgatgt agtaggacct acaaaaaaaa gtatttatga
    44641 aaatttagat gaacttaaaa atgagtgtaa attattaaag caagagactg tgtttaatag
    44701 tatcatagga tatgataata gcttaaaaga agtaatcgaa caaataaaaa ccgctgtact
    44761 ttatccaaat ggcggactta caataatgct gacaggtgaa agtggagtag gaaaaacttt
    44821 tttagccaag ataatataca aatatagtgt aagcagtaat gtattagaaa aaaattctcc
    44881 atacaatgtg ttaaactgtg cgcagtatta taataatttg gagttattgt ctagtctatt
    44941 atttgggcat gtaaaaggag catatactgg agcaaatgaa tctagagcag gtctaataga
    45001 acaatcagat ggtggtgttt tatttttaga tgaagtacat agattaaata gtgaaggtca
    45061 ggaaaagtta tttacattta tggatacagg tacgttttct aggattggag agaatggagt
    45121 aattagaaaa gctagggtaa gattaatatt tgctacaaca gaaagtctat ctgaattttt
    45181 acaaaccttt ttaagaagaa tacccataaa tatttatgtt cccaatatag aagaaagagg
    45241 gactattgaa aaaagaaaga ttgtagaaca ttttatttat gaagaaagta aggtacttgg
    45301 tttgcctata gagataactc aaattacatt aaatgcgatt ttaaagataa aattcaaggg
    45361 gaatataggt gaatgtaaaa atgtaataaa atatgcatgt ggacgagctt atgcaaaaaa
    45421 tcaaagaaga aatggaaata tttttgttac tcttcaagac cttcctagaa atctttatat
    45481 agaaaatgta gatatatttc aattccaaag tggtaaaagc aaaagcatta tcttttctcc
    45541 taaacaattt agtattgaaa tgtcaaatgg aagaaataaa agaaatataa tctatcaaag
    45601 tttcataaaa tgtttagatt actttgatag actagaaaaa aatgaaataa caaaggaaaa
    45661 atttagtaaa aagagttcta atctaatgat tagactaatg gacaatttag tcttttcaaa
    45721 taatgatgaa aataataacg tacttatgga gcttataata tcgataatgc aggatatatt
    45781 tagaaattta gaagttaata acaatataaa atatgatggg aataatgtat tggcattttc
    45841 gtcttatctt tatttgaagg acgaatctta tcaattgtct gatgagtata aagctttaga
    45901 aaataaatta ctaatatatt taaaaaaaga gagttacaaa gaatactcta taataagtaa
    45961 aatatcaaca ttaataacga atagattgga tatgtatctt aataatgtag atataatcat
    46021 aatgattata tttattaaat caacaattat aagaatgaaa tttaatcaag ttaatgcgac
    46081 tattatagca catggatatg ctactgccag tagtatggcg aatgtatgta atcggatgtt
    46141 gggtaaaaat atatttacag ctattgatat gcctatagat gctactattg cggatgtatc
    46201 aaaacaaatg tctagatacc tagagggaga taggataaag aatggtttaa ttgtgttatt
    46261 tgatatgggc tctcttaatc ttatatatga agatttaaag aataagataa atagcccaat
    46321 gttatttata gaccaaatat ccactatttc tgcactagaa gtaggaaatt tattaatgca
    46381 aggtaaaaac attgaagaga ttgcagaaat tatggatgaa gaaactaaac ctaatataca
    46441 attgtattat cctcaaaaaa ataaagaata tgctataata tcatcttgtt ttacagggat
    46501 aggtactgct ataaaaatcc aacatctact ttccgaaagt ttaattggaa tagttgatgt
    46561 caaaataata ccttatgatt atgatagtct tgtttctatg ggagataaag aaccagtttt
    46621 tgaaatgtat gatgtgatgg ctatagtagg aactgccaat ccaaatgtga atggggtaga
    46681 ttttatatta ttagaggata taatatcagg aaaaggagaa gatgatgttt ttagaatatt
    46741 tagcagagta gtagaaaatg aaaaaataaa gaacataaat gattctattg taaagaattt
    46801 ttcattaatt agagtaatag atagtctaac tattttagat tcaaaaaaga taatagagag
    46861 aatagaagaa ggaattaatg ctatagaaaa tattcaaaag aaaaaacttt caaatgataa
    46921 aaagatttct ttatatgttc acttaagttg tatgattgaa agattagtta gacaaactga
    46981 aattgaagag tatactgata tggatttgtt aatcaaaaac catcatagtg aagtaaaact
    47041 aataaaaaat gcatttagtg tgctagaaaa gagttatagt gtgcaaatac caatttcaga
    47101 gataggatat atttataata ttatctatgg tctaccacag taaaatacaa gattacaaaa
    47161 taagtgaatg aaatttaaaa aagtatgcca gtatttggca tactttttgc ttttatagat
    47221 aaatgagagt ataaacaata aaaattttaa tgtatgatgg aggatttggg gaaaatggta
    47281 tctttgatga gaattgatga cagattgata catggtcagg ttgcatatgg atgggcaaca
    47341 tcactaggta taaatgtaat actagttgca aatgatgaag caaaaaatga ccaaatgaaa
    47401 gctatgtcac tgaacttagc gaaacctagc aatgtaactt tatatataag gggggtagag
    47461 gaatctggag aaatagtaga aaaatttgct tcttcaaaga aaagcaatgt attagtgtta
    47521 gtaaaaaata ccaaagatgc tttagttgta gctaaaaatt caggaggagt attaaaagaa
    47581 ataaatgtag gaggattaag atatgaggaa gggaagaaga aacttacaga tttagttgct
    47641 gttgatgatg atgatataaa taactttaaa caaataggtg atttagggat tgatatagaa
    47701 tttagaatgt tacctagaga caaaaagaaa caactatcag atttaataaa ataatttagg
    47761 agaaagagaa tgaaaaaatt tctaattgca acacatggag aattgtccag agagcttgtt
    47821 gacacaagta aattaataat tggttcatta actaatattg agtatttttg tatgacaacg
    47881 gataaatcag cagatgatgc tgagaaagaa attagaagta tattatcaaa taataaagat
    47941 agtgaagaat ttgttgtctt aacagatgtt tttggtggaa gtgtggcaaa catatgtaca
    48001 aacttacttt tacaagggtt caaatttgaa ttattgacag gagtaaattt accaatgctt
    48061 ttatctatac ttttattagt tgaggaggat acaaaactaa tagttaaatc aggattagag
    48121 gaagcaaaaa atggaattgt ttatgtaaat gagttattag aaaatcaaaa caaaatcaaa
    48181 aatgtaatgt aatttaatgt aaattaaact aagttaaaat ggaggttcaa tatgttagta
    48241 caagctacta tgttagctat tatagcagga gttggtatac tagatgggcg tatatttggt
    48301 caatctatgc ttgataggcc aatagttaca ggtatgttag taggattagt tttaggagac
    48361 ataaaatcag gaattatgat tggtgcacag cttgaattaa tttggatggg aattgcagga
    48421 ataggtgcag ctactcctcc agatgtagta acaggaggtg tattaggtac agcttttgct
    48481 atattatcag gtaatggtgc agaagttgct ttagcagtag cagtaccagt agcagtctta
    48541 gcacaatctc ttggagtatt agttagaata ataaattcgt acttttctca aaaggcagtt
    48601 ttctatgcta aacaagctga ttttaagaaa gttaccataa tgatgtggtt gccagtaata
    48661 ttattctttt taagtacatc agttccaacc tttttagcaa ttatgattgg tgctgataaa
    48721 gttacagcat tgataaatgc aatacctaaa gttatattag acggactggg tgttgcagga
    48781 acattgttgc cagcagtagg ttttgcattg cttatggata tgttactttc aaaaaagatg
    48841 tctgtatttt tctttatagg gtttttgtta gcatcttatg gtggattaga tataactgct
    48901 atagctttat ttggagtatg tgtagcattt gtactaaact tttatatcaa taacaaagaa
    48961 aataatcaaa atcctcaatt agcaatcaat actttaacgg aaggagagat tgactttgaa
    49021 taaattaaca aaaaaagaat taagaagtat gttttggcgt tcatttgctc ttcaaggtgc
    49081 atttaattac gaaagaatgc aaaacttagg ttactgttat tcaatgttac ctgcaataaa
    49141 gaagctatac aataagaaag aaaatcaagc aaaagcaata gaaaggcatt tggagatttt
    49201 taatacaacg acagtagtag ttcctgctat attaggtata acagcagcta tggaagaaga
    49261 gaatgctaat aatccagaat ttgatgaaag ttcaattagt gctgttaaaa cagctcttat
    49321 gggacctctt gcaggaattg gtgattcatt attctgggga acatttagga ttatagcagc
    49381 aggagtagga gtatcacttg caaaagaagg taatatcttt ggaccactat tattcttact
    49441 attatacaat ataccagcat ttgcccttag aatatttgga cttaagtatg gttatcaagt
    49501 aggggtaaat tctcttgaaa gaatacaaag agagggactt atggagaaaa taatgtctat
    49561 ggctacaact gttggtttat tcgttgtagg aggaatggtt gcaactatgt tgagtataac
    49621 tactcctctg aaattcaact taaatggtgc agaagtaatt ttacaagata tactagataa
    49681 aataatacct aatatgttac ctttaacctt tgcatttgta atatactaca tgttaaagag
    49741 aaaggtaagt gtaacaaaat taactatagg cactatagta acaggaatcg ctttacatgc
    49801 tataggtttg ttatagaaat taattataat ttattgaata tatagataag gaaggtgtat
    49861 aaaatgacaa tacaagatta tatgttagaa acaccagtta gaatgagaga aattatatct
    49921 aatgcagata gcttatttaa tgaagttaag agaacaaatc taaaaaagat tataataaca
    49981 ggttcaggta ctagctatca ctcaggagtg caagtacaac catatttaca aaatttatta
    50041 gatatagatg ttgtgaaaat gtatccattt atgataactg aagatacatt caagtttgat
    50101 aatgaaaata ccctagtagt aggtgtatct caaggtggga gtagttattc tacatacaac
    50161 gctatgaagt tagctgaaga taagggctgt aaaatagcat ctatggcagg ttgtaagaat
    50221 gctttaatag atgagatttc tgattatata ttaacagtaa attgtggtga agaaaaatct
    50281 ggagctaaaa caaaaggata ttattgtaca aagttaaact taatgttatt aggtcttcaa
    50341 atagctagag aaaaaggtat aatatctagt gaaaagtaca atgaggaaat aaataagata
    50401 ttagacgcaa ttaatagatt tgaagcagtg tataagctct ctaaacaatg gattgaaaga
    50461 aacaaagaaa agttagttaa ttctaaagaa ataagaataa taggtcactc tgatatatat
    50521 ggagatacat tagaagcagc attaaaatta ttggaaacaa tgagaatacc tgtaactggg
    50581 tatgagtttg aagagtttat acatggtata tataatgcta taaatagtga ttctactata
    50641 tttatactag atacaggaaa agaacctaga gtaactaaga tgattgatgt actttctggt
    50701 tggacggaaa atgtatttgc tataggtaga gatgttacag aaaatgataa aaatttaaag
    50761 attgatatca cagataatcc ttactatcaa acatttaatt ttatagtacc tatacaacta
    50821 atatgtgggg aaatacctac attaagaggt gtagacccaa gtgttccaaa agatactagg
    50881 ttccacatga agttaggtag caagaaactg aataagtaac aaaaaaagag gttgtctcaa
    50941 aatagagata agcctctttt ttactagata agctcttttt tactgttgaa atgatgaaaa
    51001 tatatttgat tttctataaa aaagagtgcc tcatgaacta aaaagttaat tttgagacac
    51061 ccacttttat cttattttaa actaaaatat ttatatatta gtgtgcatta ttttttttat
    51121 tgctgtcttc cttacttgag caagaattag cacttggaca tccagaacaa atagaacatc
    51181 cactacagac atttccgttt tttgtagact tgaatttatt aaacagaata aagagtgcaa
    51241 ggactataat tattccacct atcaaagctt ctattattga attacccata aatagtactc
    51301 cacctatact tttaactata aaagccatta tccatgctag tataaattga tatgcaaatg
    51361 atgtaaacat cattttattg ccatattctt ttttcatagt tgcaagtgca gctatacatg
    51421 gagtatataa agcagtaaat atcaagaatg tatatgcagt aactccatta aatattgttg
    51481 gtaagacaac agttagatta ccatatagta tatttaaaga gtttactacg atttcttttg
    51541 ctccaagacc acttaaaata gcaactgaag ttctccaatc atcaaaacca agaggtttga
    51601 atataggaga tataatatga cctagagtag ccaagaagct tacatttata tcttctgtat
    51661 atccaaaaac attgaatgaa gaaagtcccc aaattacgac tgacattgca aacatgacag
    51721 taacaactct tatcaagaaa ccttttgatt tattccaagt atttttaata agtgcatcta
    51781 tagtagggat tctatattct ggtaattcta atataaatgg ttcagcctct gttttaaagg
    51841 ctgttttatt taagaataat gcaactacaa ttgccataac tatacccacc aaatacagtg
    51901 atgtagttac taaagcagca ttatgtggaa agaatatagc tacaaatagt gcatatatag
    51961 gtagctttgc tccacaagtc ataagtggtg caataagagc tgtaactctt ctatcttttt
    52021 cgctttccaa tgttctagtt gccattatag ctggagaaga acatcccata cccataacta
    52081 taggtataaa agctttacca gatagaccaa cctttctcat aactttatcc attaaaaatg
    52141 ctgttcttga catatatcca ctatcttcaa acaacgatat accaaagaat aatgtaaata
    52201 ttaaagggaa gaatggtaaa gtaccaccaa cacctccaat tattccatca actataagtg
    52261 atttaaacca tgggctagag ttagataaca tatcactaac aggtgcagaa atataagcct
    52321 ctataagact agcaaatccc tcttgtagtg gtcctccgac ccagtcaaag gtaaatttaa
    52381 ataagaggaa caatacacca ataaatatcg gatatgctaa tataggattc aagactatat
    52441 tgtctatctt atcactgata gatttctttt gtgtatatgt agtttttgta catctcgata
    52501 aaatggattc taatttttta tatgtttctg tttcacttcc aaagtttttc tgatatataa
    52561 aagctttttg cgtagctccc ttaatctctt cttctatcct atcaacacca tttttctttt
    52621 ttgctataat tggaacaaca attactccaa gttcttcact taattttttg gcatctatat
    52681 taactccttt agattctgca atgtctaaca tattaagcaa tataactata ggcttgttaa
    52741 attgcataag ttgagttgtt aagtaaaggt ttcttgataa attagaagca tcaactacat
    52801 ttactattac atcaacatct tcattttcta aatatgattt agaaaccttt tcttcatttg
    52861 agaaagtatc cattgcatat ataccaggta aatcgacaac ctttatctct tttccaagaa
    52921 atccttcttt tttttctata gtaacaccag gccagttacc tacatattga tttgaacctg
    52981 taagtagatt aaaaacagta gttttaccga catttgggtt tcctaataat gctacattaa
    53041 tcacgggtag ctcctcctct attattgtaa agaaatattt ttagcatcag attttctaat
    53101 cgcaaggtca aagcctctaa atctaattat aattgggtct ccaagtgggg caaccttttt
    53161 aacttctatt tcagtactat ttatacatcc aagtgcaagc aatcttttag ataatttaat
    53221 atctccatct atactattaa taaatccttt ttctcctatt tttaaatcgt aaacagtcat
    53281 tattaacacc tcctaatgaa attcattatc attaaaattg taacaagtat gatacaaaaa
    53341 gtcaagattt atagaggtaa ttgcacattg aaataactaa tatttattct aaatagatta
    53401 aaaatatttt agtctaaatt aggtgttttt atatattttg tattataatg taagatgata
    53461 gataaaattt ggaggagtta acttaatgaa aactagaaaa atgacatttt taggtcttat
    53521 gatagggtat agtttagctt tatatgtatt agagacatat ataccaaatc ctcttatagt
    53581 tatatttcca ggggcaaaat tgggtttgag caatattata actttaattt cattaatgtt
    53641 gttaggtgtc aaagatactg ttataattgt tactatcagg gtaattttgt catcaatatt
    53701 tgcaggccct ttatcatatc tactatttag tataggagga gcttatctga gtcttttatt
    53761 tatgtattta gcgagtaaaa taaaagattt atcactaata gggataagca ttataggtgc
    53821 aatagggcat aatataggtc aattaatagt tgcaagttta atcatagaaa atatacttgc
    53881 tatagggtac ttaccattta tgttaatggc atcattagta actggtatgt ttgtaggctt
    53941 agtatccagg tatacaatac ctaaattaaa gcatttttat agtaagtttt attgacataa
    54001 tattgacaaa atataatatt gtttgataaa atgtatataa aaatatacaa atttgtaata
    54061 gtggtgatta ttatggcgaa caatgaatta gaagcgttaa aaaatgagat tgaagcagtt
    54121 agggaagaga taaatacata catagaatat ccagaaatat ttcaagaaga gttagtagaa
    54181 tcaagtaaga aaatagatat attaataaat aaatacatgt acctaagcaa atagcccaca
    54241 gttgtgggtt tttttgtatc aaaaattaac agatggctat attttacata tattaataat
    54301 aatattaaga tataaaatag tatttctgat gtgtaaatta tctgtaggac ataagttgta
    54361 attaagtcag gagggtttta tattatgatt gatataggaa gtaaggagat agcaataagg
    54421 ttactattag cactaataat aggaggaata ataggcttag agagagaaaa aataagacag
    54481 tttgcaggat ttaggacaca tatactaatt gcaataggtt cttgtattgt ttcaataact
    54541 tcgattcaat tattctttga ttataatttg tatacaaatg ctgacccagc aagaatgcct
    54601 gctcaagtat tatctggaat tggtttttta ggtgcaggag caattttaaa aaataaaggt
    54661 ggagtaaaag ggcttactac agctgctggg atgtgggcaa ctgcatgtat tggtatagca
    54721 gttggatatg gttattatga attggcaatt ctaggtggat tatttgtaat gatagcatta
    54781 tttgtgctta ggataatcaa tacgttttta tttagccaag aaaagaatgt attgatatta
    54841 aaattaagca atttggattc tatacctttt ttatatgata aatttgaaaa aaatcaactt
    54901 atcgtaagaa atatggaaat agaatgtcgt aatgaagaat actggaaggt taattttttt
    54961 gtatcttatg ctaagagaat acacttacac gacgttatga aagaaataaa tatgatagaa
    55021 ggagtaataa atgtagatta tttggactaa aatatataca atatattttg taaagtgaat
    55081 aaaatataaa acaaattaaa atagaggtgt atgatatggg aactgataga agtacaatag
    55141 aagaaaagta caaatggaag atagataaga tgtactccag taaagaggaa attgaaaaag
    55201 acataagtaa agtaaaaaat cttatccaag aagtaaaaga atataaaggg aagctttctg
    55261 agagtaagga gaacttatat aaagtattaa atatctctga aaatgcatct aggattgttc
    55321 aaaatttata tgtatatact catatgaaac aacatgaaga tactagaatt aatgataatc
    55381 aaggaagagc cactaagaca gaaatgttat ctactgattt aggtgtggct acttcttata
    55441 tagttccaga aatactggcg atagaagaga ataagttaag tgaatactta aaagatgaga
    55501 agctatcctt ttatgcaaaa tatataaagg atatattgag agataaacca catactttga
    55561 gtgaacgaga ggaagaaata cttgcagcta catcagaatt atcgacaatt ccagaaaatg
    55621 tatacgatat gttagcatat gcagatatgg aatttcctga gatagaagat gaggagggga
    55681 ataaggttaa gctttctcat tcaaactact ctttatttat aaaaagtaag aatagtagag
    55741 ttagaaaaga cgcttttgaa ggtgaatttt caacatatga gaaatataaa aatacatttg
    55801 cctcaacgct ttatggtgga ataaaatcag agatatttta cgcaaaaact agaaagtata
    55861 attcagcaat agaagcgtct ttattttcag atgatgtaag tttagatgtt tacaataatc
    55921 ttatatcagc tatagataaa agtattccta atctaaataa atatgttgag cttaaaaaga
    55981 aatttttagg attgaatgaa atacacatgt atgatttgta tgttcctttg acagataaat
    56041 ttgacatgga tataccatat gataaagcac aggatatcat attagaggca cttaaacctt
    56101 taggagaaga atacttgaag gtcataaaaa gtgcttttga tgaagggtgg attgatgtat
    56161 atgataatga aggtaaaaaa ggaggagctt attcttgggg aagttatgat tcacatcctt
    56221 atatattaat gagctataaa aatgacctta attctctatt cactttaatt catgaattag
    56281 ggcactctgt tcacagtcat tattcaagaa caagtcaacc atttttatat tcggactata
    56341 agatattcgt tgcagaagtt gcatctacat taaatgaatt acttcttata aattatttat
    56401 tagaaaattc taagtctaag gatgaaacta tatacttatt aaattattat ttagaacaat
    56461 ttagaactac agttcataga caaactatgt ttgctgaatt tgaaaaaatt gtacatcaaa
    56521 gggtagagag tggagaacca cttactgctg atgaatttac taatatatac tacaaattaa
    56581 atgaaaagta ttacggaaaa tctgcaatag tagataaaca aataggaata gaatgggcga
    56641 gaatacctca tttttattca aacttctatg tatataagta tgccacaggg ttttctgctg
    56701 caagtgcttt aagtcaacag atactttcag aaggaagtac tgcagtagat agatatataa
    56761 acttcttaaa aagtggaggg tcagaatacc cactagaaca attaaaatct gctggtgtag
    56821 atatgacgaa aaaagaatct atagaggaag ccttaaatgt atttgctgaa ttagttaata
    56881 aactagaaaa agaattatag gatgtgatag gttgatagct tcaatgaaga cttctgataa
    56941 tatgagttgt attatgttta tatctgccta aagtaacttt aaaaagttaa tctaattaag
    57001 aataaatcat ataaaattaa gtttttacat gtatttaaca atatttacat ttacttaacc
    57061 ctgctctaat attcatttaa caaagaatct gtattattaa aatatagaaa aatgacaaca
    57121 aaaaattaaa atataagcgg gggtaagtaa aatgtttaaa aagaaaatag gcgttctttt
    57181 agctagtaca atgttagttg gagctttagc agtaggatgt agttctaact caggaggttc
    57241 aggtgattca ggagattcaa gcaaagtttc tgtttcaggt tcaacttcaa taggtcctct
    57301 tatggaaact atcggagaaa agtttcaaga aaaaaatcaa ggtgttagtg tagaagtaca
    57361 acagattggt tcttctggag gtataaaaaa tgctatagaa ggaacatctg aaataggaat
    57421 gagttcaaga gatttaaaag atgaagaaaa aagtgctgga ttaaaggaaa ctaaaatagc
    57481 aatagatggt atagcattga taactaatac tgcaaactca gtaaaaaatc tgacaatgga
    57541 ccaagttaaa ggtatatata caggaaagat tactaactgg aaagaagtag gaggaaatga
    57601 tgcaccaata gtaatagtat caagagaaga aggttcagga actagagatg gattccaaga
    57661 aattgtaggg tttgattcag aagaactaac taaagatgca caaataagtg atggttcagg
    57721 aaatataaaa actacagttg aaggaaatga aaatgctata ggatatatat catttggata
    57781 tgttgatgag aaagtaaata gtttaaaaat aaatgatgtt gaagcaactg atgcaaatgt
    57841 aatagctaat aaatatccaa tatcaagacc atttatatta gttaataaag aagatggttt
    57901 gtcagaaaaa ggtaaagctt taatagatta tatattaagt gatgaaggac aagcacttgt
    57961 ttcagaaaaa ggatttatta aagttaatca ataacaagag ttataatata aagtaaacat
    58021 ataataccct gtgagataag ctcataaaaa tgatgcttta acttgcaggg tattgtctat
    58081 tattgaatgt agaaatataa atatctttag ataaaatagg tattttagta tcttatctct
    58141 aagaatatgg aaatattgac aaaataatat tacaatgtta gaataaaaaa gaaatttatg
    58201 aaaatatata aaagattttt aataaaaata ttttagaaac tgagaagtat atcttattat
    58261 tgggcatcta gagatatatg gagttagtgg tgcaaccggc tatgaatata atttttatat
    58321 tgcatagtct ttttttgttt taaaattaac aaatatgttg caaaatttga aaataagagt
    58381 attagtcgtt aagattttta ttgataggta aaattttggc ttttaaagta gccatttgtt
    58441 ggaaaaggga aattttttta aaagaataat agtattataa taagaaaata aagtttttat
    58501 aaacattgag atgcagaata taaacctttt gtaacaatat atttaccaaa ataatacaat
    58561 ttattttata ttataaccat ataaatcata taaatcaata ctcaaactag ccaatagaca
    58621 agtttctaga aaaataataa atttatacgt gaaaatgact ttaagctcca ttctccaaca
    58681 atcggagact ttaattagta tttaataatg aatcttaatg tttaatacaa tattcaagaa
    58741 ttattcaaaa atacttaagt attatagtct agtttgtaaa gatattataa aataataata
    58801 ccagttatat atgaaaataa aacattataa tttgtaataa ctataaaact tggaattata
    58861 attaaaatac ctttgaatgg agtggtgtaa tgtataattt actggttgta gatgatgatg
    58921 ttgatatttt aaacataaat caaatttatt tttctaatat aggttttaat gtatatacat
    58981 cagagactgc taaagatgct atggatatag tagagagtat agttttagac tgtataattt
    59041 tggatatttc attgccagat atagatggat ataaaatgtg caatgatata aaagaaaagg
    59101 ttaacatacc tataatattt ttatctaatt atgagcatga agaagaaaaa gttcggggat
    59161 ttttagctgg gggggatgat tatataacaa aaccttatag tttaaaagaa cttgaactta
    59221 gaatatatgc tcgtatgagg cagtacaaaa atattacatc agttcctaat gtgttaaagt
    59281 tttcagcgtt agtaataaat gtaaattcaa gaaaagtaac ttttgatgga gaaagtatag
    59341 atttaactac tatggaattt gaaatattat tgtttctagc tgaaaacaaa gaacaagtat
    59401 tttcgaagat agagatatat aaccaagttt ggaaaatgcc tgatattgga gatcaacata
    59461 cagtgcaggt tcatattgca cagatgagaa aaaaaattaa ttctttaagc agggagcatc
    59521 aatacattca aaccgtatgg ggaaaaggat ataagtttgt accataagtg agatactgta
    59581 attaataaat agttcttgtt ttatttaata ctactatgaa agagatgtgg ttgatacaat
    59641 gaaaaagtat aatatactaa aaggaactct cattgtattg atagtctctc tgttggcaat
    59701 aacaggatta aatcttctgt ataaatatga taataaatat acatataagt ctattagagc
    59761 aagtaatgga attttaacta tagataatga tactttcact aaaggtaaac ttgtcttttt
    59821 gatagatgac tgggagtttt ataatcataa aatatttaaa ccgaatgatt ttacagagca
    59881 agatataaaa ccagaatatg tttttatagg tcaatatcca gatttttcta tgagaaaggg
    59941 gactcagtca ccatatggga atgctactta tcgtatgaga ataaaaaatg aaggcaagga
    60001 taagctacta agtttagagc ttcctgagat tttttccgca agtgaagtat ggataaatgg
    60061 agaaatggtt tctaaattag gagatgtagg aacagaaaaa tatagaccca aaattaaaaa
    60121 ttcagtagta agttttattg caaagaaaaa tacagaaatt ataatcaatg tatcgaattt
    60181 ttcacattat tatagtggtt tgtattatcc gcctgcatta ggagaaacaa aggacataag
    60241 taatatgatg ttttatcgat tactttttta tagtataatt tgcttcacaa cttttgcaat
    60301 agctatattt tcattgtctg tatggtttct ttcaaacaaa agtaaaattt acttatattt
    60361 tggatgtatg tgtgttttct ttgccatcca tgtatcctat ccctttgtac atttgttagg
    60421 actgcctttg gtaagcttta catatgcggt tgaagatttg tcatatttta tggtagtttt
    60481 atgtattatt tgtataaatg gaagtatatc caaaatagaa gaaaataaag tgtacagatt
    60541 tttaatttta ccattaggaa ttacaatgag tatcatatct atagtgatac caattattct
    60601 tcttccatat gatatgtact ttgtcaacat atatgggaag ttaatagaca tatataaata
    60661 tattgtattt atatatatat taatgtcttc gctggtttca atatataaaa agacatgctc
    60721 tgagcatata agttcttata ttttagtttc agtaaacact gtttttggaa ttagcatatt
    60781 atttgatgca gttacgagta atagatttga gcctatattt acagggtggc aaacagaata
    60841 ttgtgggttt gtaattgtta ttttattttc tgttatgatg ataaacagga atagaataat
    60901 aataaaagag aatgaaaaac ttacaaggaa tcttgaacat gaagttgaag tgagaactaa
    60961 tgaacttaca acattgttaa atgaacgtaa aagattcttg gcagatgtag cacatgattt
    61021 aaaggcacct gtttcggcta tacaagcatt tatagatttg ataaaggttg gtaatattca
    61081 tgtagatgaa gagacaagaa cctatcttta tgctataaat caaaagtcaa atgaagtaca
    61141 aaatagagta cgtagtttgc aagaatttac atcacaagat aaaagcattg gtattagtga
    61201 aaaaatatgt ctgaataatt ttattaaaga gatatatgaa aataatttgc cagatacaca
    61261 agcatgtggt gtaaactttg aaacttacgt attggagaaa aaaatatatg caaagataaa
    61321 taaagagatg cttacaagag catttgagaa tttaatttat aatgctttga cctttactcc
    61381 atttgatgga aagataattt tatcaatgga taaagaagat ggatttgcaa ttattaaaat
    61441 ttctgataat ggaaaaggta tacctccaga aaatatacca aaggtatttg acagattctt
    61501 tacagaaaga gacaataatg agccaaaagg gcaagggtta gggctatata ttgtcaaatc
    61561 cattataaga gagcatggtg gagaaatctt tgtagattca gaactaggaa aaggaactgt
    61621 ttttacaata aaattaagtc tatatttttt ataataatag cttatttaat ataaaagaat
    61681 aatgatattt gggagtgatt ataatgcaaa ctaagatatt gataatagat ggagacaagg
    61741 ataattgcaa gaagctaaaa ggatttctgg aggaaaaagg aataagtata gatttagcat
    61801 ataattgtga agaagctatt ggaaaaatat ttagcaataa atatgattta atatttttag
    61861 aaataattct aagtgatggt gatggatgga ctctttgtaa aaaaattaga aatgtaacta
    61921 cttgtccaat tgtttatatg acttatataa atgaagacca aagcatttta aatgctttaa
    61981 attctggtgg agacgattac ttaataaagc ctctaaattt agaaatatta tacgcaaaag
    62041 taaaagctat tttaagaaga atgaactcat atgtaaataa taatgaaaat aatacaaaat
    62101 tagaggaata taatagaact agtggagtaa taaagttaga agataaaata ataaaattga
    62161 ctccaacaga aaataagttg ttaaactttt ttatagagaa tcctgaaaag actttgacta
    62221 ctaaagagat atatgaacat gtatggatga atgaatactt agaggataac tatagtgtgg
    62281 tagttgcagt gaatggatta agaaagaaaa tagagaaaga ttataaaaat cctcagaaaa
    62341 ttataacaat aagaggagca ggatattatt ttaataaaga ataataaata tattaatatc
    62401 attaataatt gttataaatg tgaaatacta acaatatcta aactaaatta ttataaaata
    62461 gctgactgta atttaattga taaagcctat tcttctagac tttgccagtt aaattacagt
    62521 cagttttatt atataaaaaa atgcgtaatg gaactattat tttatagatt atatt
//
LOCUS       DAYAOO010000013        61104 bp    DNA     linear   BCT 12-OCT-2024
DEFINITION  TPA_asm: Clostridioides difficile isolate ST8-SSI-h139-18
            SAMN40601845-rid21577343.denovo.013, whole genome shotgun sequence.
ACCESSION   DAYAOO010000013 DAYAOO010000000
VERSION     DAYAOO010000013.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN40601845
            Sequence Read Archive: SRR28438827
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 61104)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 61104)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-MAY-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-MAY-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002157583.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002157583.1
            Genome Coverage       :: 163x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/11/2024 16:19:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 4,038
            CDSs (total)                      :: 3,963
            Genes (coding)                    :: 3,930
            CDSs (with protein)               :: 3,930
            Genes (RNA)                       :: 75
            rRNAs                             :: 6, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 60
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 33
            CDSs (without protein)            :: 33
            Pseudo Genes (ambiguous residues) :: 0 of 33
            Pseudo Genes (frameshifted)       :: 7 of 33
            Pseudo Genes (incomplete)         :: 25 of 33
            Pseudo Genes (internal stop)      :: 11 of 33
            Pseudo Genes (multiple problems)  :: 8 of 33
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..61104
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN40601845-rid21577343.denovo.013"
                     /isolate="ST8-SSI-h139-18"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Denmark"
                     /collection_date="2018"
                     /collected_by="Statens Serum Institute"
     gene            complement(63..2033)
                     /gene="ftsH"
                     /locus_tag="ACGI5H_000931"
     CDS             complement(63..2033)
                     /gene="ftsH"
                     /locus_tag="ACGI5H_000931"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892124.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0004222 - metalloendopeptidase activity
                     [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA];
                     GO_process: GO:0051301 - cell division [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent zinc metalloprotease FtsH"
                     /protein_id="HFG9696655.1"
                     /translation="MNKLLKGAGFYLLVFIIIVGIVQFSGKPTEKIKDLKFSEVYREL
                     TDENISRLYFVNQTSVEGTIKDTNTKFKSYVPTEVMGNKLADEVLDQAKAGKLTFGGE
                     AKPSTPWFVEMLPTLLLIFFMVIIWFVFMNQSQGGGGKVMSFGKSKAKVHKDDEKTRV
                     TFKDVAGLDEEKEDLQEVVDFLKNPKKYIELGARIPKGMLMVGPPGTGKTYLSRAVAG
                     EAGVPFFSISGSDFVEMFVGVGASRVRDLFEQAKKSAPAIIFIDEIDAVGRKRGAGLG
                     GGHDEREQTLNQLLVEMDGFGVNQGIIIMAATNRPDILDPALLRPGRFDRQVVVGTPD
                     VKGREAIFKVHSRNKPLSDDVKMDVLARRTPGFTPADIENLMNEAAILTARKREKKIK
                     METIEEAITKVIAGVAKKSKVISEKERRLTAYHEGGHAVCAHVLEEVSPVHQVTIVPR
                     GRAGGFTMQLPVEDKFYATKNEMKENIIVLLGGRVAEELVLKDVSTGASNDLERVTAT
                     ARSMVTKYGMSSKLGPMSFDSDDEVFLGNSFSSKRNYSEEVAFEIDQETKRIVDGAYD
                     KTRSILQENMDRLEYVAQALLIYETLDAEQFVKAFNKELPLNEIENAVTEENSSKEVE
                     EQLTIKLEKDEEERNNVIDINKNLEDKSDKDK"
     gene            complement(2067..3455)
                     /gene="tilS"
                     /locus_tag="ACGI5H_000932"
     CDS             complement(2067..3455)
                     /gene="tilS"
                     /locus_tag="ACGI5H_000932"
                     /EC_number="6.3.4.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898757.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016879 - ligase activity, forming
                     carbon-nitrogen bonds [Evidence IEA];
                     GO_process: GO:0008033 - tRNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA lysidine(34) synthetase TilS"
                     /protein_id="HFG9696656.1"
                     /translation="MIFDKVLSTINKHNLIQKGDKIVLGLSGGPDSVCLLHVLNRLKK
                     DFNIEIYAAHLNHQIRGIEAQKDALYVSKLCEDMGIIFFVKSINVPKYCENEGLSLEE
                     GARKLRYEMFYEIKDKIKANKIAIGHNLNDQAETVMMRIMRGTGLKGLKGIDYIRDNC
                     IIRPILDVERNEIEEYCEAYNLNPRIDKTNLENIYTRNKIRLDLLPYMKDNFNSNVIE
                     SIVRMSNSLKSDNDYIEKEAEAKFREVSNIKEKGFVEINLDDFVCLHDAIKVRVLRNS
                     IKHILGDTNFVDQRHIEDIMSLEDNSKVNKMLTLPRNIFVYRKKDSIILTNEEIVNEE
                     IEFYYNVPSNGFIKIKELKQIIETQVMSIDRYKSMKLDNSSKGFDFNKVKGGIVIRSR
                     RQGDKIKLAMGSKKVKDLFIDLKIPREERCKIPIITDGEGIICVGDYKISENYKIDES
                     TKEVLKINFNKL"
     gene            complement(3638..4066)
                     /locus_tag="ACGI5H_000933"
     CDS             complement(3638..4066)
                     /locus_tag="ACGI5H_000933"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012816442.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1934 domain-containing protein"
                     /protein_id="HFG9696657.1"
                     /translation="MEEKSLSVKISINTRQYDEKGNMDTIEMTAFGKIFYKNDGIYVI
                     YKEKEEDIEITNTIKILKNQVSIKKFGAINSTMLFKCGESSTTKYVTPQGTLLIDIDT
                     RELDINIQEGEHIKLKIDYNIKVQDLFLGRNKIDIYIGTK"
     gene            complement(4083..4889)
                     /gene="murI"
                     /locus_tag="ACGI5H_000934"
     CDS             complement(4083..4889)
                     /gene="murI"
                     /locus_tag="ACGI5H_000934"
                     /EC_number="5.1.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425992.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008881 - glutamate racemase activity
                     [Evidence IEA];
                     GO_process: GO:0009252 - peptidoglycan biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate racemase"
                     /protein_id="HFG9696658.1"
                     /translation="MNNKPIGVFDSGLGGLTVLKEIMKILPNEDIIYFGDTARIPYGS
                     RSKETIIKYTFQAINFLKTKGVKAIVIACNTATARSLKEAQEKYDIPIIGVIEAGART
                     AVSSTKNKIVGIIGTEGTISSKAYNLEISKIDESIEIVNKACPLFVPIVEEGWANTEV
                     AKLTAKIYLQELKEKNIDSLVLGCTHYPILKRTIGEEVGEHIKLVNPAKETAKDLKKI
                     LEVQNIINNTEIHGTYQYYVSDIPEKFSDIAREFLKKKIDKIQKVEIQKY"
     gene            complement(5091..5597)
                     /locus_tag="ACGI5H_000935"
     CDS             complement(5091..5597)
                     /locus_tag="ACGI5H_000935"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434944.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall hydrolase"
                     /protein_id="HFG9696659.1"
                     /translation="MDRWSKLMATLLALTFIFMPIKEVFAYEPTENIKKVNKQEKNIA
                     KKEVINLSDNDLMLLSKLVAGEARGESYEGQVAVAAVVINRVLDPRFPDTIEEVIYQK
                     NAFSVVLDGSIKMAPTDSARKAAQEALYGTDPTNKAVYFWNPEIATCKWINRLNPYMR
                     IGNHVFAK"
     gene            complement(5627..6286)
                     /gene="spoIIR"
                     /locus_tag="ACGI5H_000936"
     CDS             complement(5627..6286)
                     /gene="spoIIR"
                     /locus_tag="ACGI5H_000936"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425996.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003674 - molecular_function [Evidence
                     IEA];
                     GO_process: GO:0030436 - asexual sporulation [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="stage II sporulation protein R"
                     /protein_id="HFG9696660.1"
                     /translation="MRKIKIRLGLLILSLISVISIMTIVINGEVKKVDNISKDYKDKL
                     IRFHVIANSNTDEDQELKLKVRDEVIKYLQPKLQNSKSIKESEAIIKKEYSSLEEISK
                     NIILKNGYNYSVKVGIQYSNFPTKQYSNIVLPAGEYKALKIIIGKGEGKNWWCVMFPP
                     LCFVDESNGVIDKSTDDKLKEVLTDKEYKLIKQDTPKKTSRVKIKFKVLEVVKDLEKK
                     F"
     gene            complement(6431..7111)
                     /locus_tag="ACGI5H_000937"
     CDS             complement(6431..7111)
                     /locus_tag="ACGI5H_000937"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009906549.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HFG9696661.1"
                     /translation="MENLTKLNLDNYKPLRDVVFENLREAILEGKLKPGQRLMEVQLA
                     EQLGVSRTPVREAIRKLELEGLVVMLPRKGAYVANMSLKDIMDVLEVRASLEGLAAYL
                     AAERISDEDIKKLKDISEEFKKSTLESDVDALLKLDVEFHECIFKATNNKKLIQLINS
                     LWEQVYRFRVTYMSAYDTSHNIVEEHKYLLDAIIKGDSELSKKYATEHIEKAEQFMID
                     KAMISKDL"
     gene            complement(7095..7985)
                     /gene="ispE"
                     /locus_tag="ACGI5H_000938"
     CDS             complement(7095..7985)
                     /gene="ispE"
                     /locus_tag="ACGI5H_000938"
                     /EC_number="2.7.1.148"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004453273.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0050515 - 4-(cytidine
                     5'-diphospho)-2-C-methyl-D-erythritol kinase activity
                     [Evidence IEA];
                     GO_process: GO:0016114 - terpenoid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="4-(cytidine
                     5'-diphospho)-2-C-methyl-D-erythritol kinase"
                     /protein_id="HFG9696662.1"
                     /translation="MDFIRLKSRAKINLSIDVLGKRQDGYHFVEMIMQTIDLYDIVKI
                     KELDEDEIKVKSTSLDIPLDEDNIVYKAAKILKNKFYIKKGVEIFIEKNIPVAAGMAG
                     GSSNAAAVLVGLNHLWELRLSEDELKEIGLNLGADVPFCISGRPALAQGIGEKLTNIK
                     GLPCDTNILICKPDLFVSTKEVYQGLDLNNIKKRPNNKYLIECLKSEDIKAVSESMVN
                     ILENVTIGKHKEISDIKQVMMKNNALGSMMSGSGPTVFGLFKNKEDALIGKKELLKKY
                     KQVYVVNSSQKGVEICGEFN"
     gene            complement(8103..9653)
                     /locus_tag="ACGI5H_000939"
     CDS             complement(8103..9653)
                     /locus_tag="ACGI5H_000939"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898760.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SPOCS domain-containing protein"
                     /protein_id="HFG9696663.1"
                     /translation="MELIKDVIKVDNRIDFGKFQTFIEAEAVVPDKKLDVYEIVKTEG
                     YISLKKIEMADGKILCRGSFNYNVIYIADDKNTISNVDGKVDINEVIEKDNVIQDMEY
                     MLFSEVEHMDCTIMNERKIKVGALMNIRGSLFEKQRLDIVKDVAQVECIQKHRKEICF
                     QDIVGIEKAESSIRDTITINTEEIQSIISLNPCVKVKESRVTDNKVIIGGVLEINPLA
                     CTYEGELVELDRVGIEFTQFVEVPGVSDGMTEEVLLSMSDFNHIFKQNSESNTGLLEI
                     DCMACCKVKVTDEVTREVLQDAYSPQKIIKFDHKPIQLNKTLRRSEETFMVREGIRND
                     NDDIQIKDIVSVCPTMSIENSYIEGNKSIIQGIIKVEILFVPVEGLKLVYKISEEIPF
                     EHDIEMDNLTDTASVFNTACIDKVEVDLNRDQIDLIIKIKRFTEALDKKAENFIIKGE
                     DQGVYDLSKAPSIIVYICKEGDTFWNIAKKYNTTENEIAELNDIKLDEPIKPGKCLIL
                     EKKVVLVD"
     gene            complement(9747..10013)
                     /locus_tag="ACGI5H_000940"
     CDS             complement(9747..10013)
                     /locus_tag="ACGI5H_000940"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892135.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Veg family protein"
                     /protein_id="HFG9696664.1"
                     /translation="MATVQTLDKIRVSLERHIGKKILLKANKGRKQIITKEGILEKVY
                     PSVFVIKLDDESNGYPRVSYSYSDLLTSNVKLQVFRDQDKLQIS"
     gene            complement(10161..11021)
                     /gene="yabG"
                     /locus_tag="ACGI5H_000941"
     CDS             complement(10161..11021)
                     /gene="yabG"
                     /locus_tag="ACGI5H_000941"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422239.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008233 - peptidase activity [Evidence
                     IEA];
                     GO_process: GO:0030436 - asexual sporulation [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sporulation peptidase YabG"
                     /protein_id="HFG9696665.1"
                     /translation="MKVGDIVARKSHNKDIVFKIVSFGVDENNEKIAILKGIAFRVIA
                     DAYIDDLELVKAPDIKDILIDKNVENLLYKSVRKAKERQKRMTRAVPKLQLNPNTYGM
                     PGKVLQIDGDKEYLKICLDVYAQLGIPAVGVAVSEQNQYKEVRALLEKYNPDILVITG
                     HDAMTIKRGDIEDMSNYRNSSNFVKTVKEARKWQPNLDNLVIFAGACQSNYEKIISAG
                     ANYASSPGRIMIHALDPVFIVEKIACSRIDVVVPIDEVIEQTITGVKGIGGSETRGKF
                     RWAMPKTILH"
     gene            complement(11105..12043)
                     /locus_tag="ACGI5H_000942"
     CDS             complement(11105..12043)
                     /locus_tag="ACGI5H_000942"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898762.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dipeptidase"
                     /protein_id="HFG9696666.1"
                     /translation="MKFLDLHCDTIAKLMENVETSELKSNKYSVDIDRLKKGDSLAQT
                     FALFVDTEEVKHPFDYCMSMANKFHEEMKKNSDEIALATNYEEIMKNQSEGKLTALLS
                     IEEGAVLEGKLENLKKFYDLGVRMMTISWNHVNELSFPHNKVEYREKGLTDFGREVVH
                     KMNELGMLVDVSHISDGGFYEIAKISSKPIIATHSNSRAMMNHSRNLTDDMIKVLANK
                     GGVTGINFFHLFLSDKSESKLEDMVRHIKHIVNVGGIDVVSLGSDFDGIDSKVEIEDI
                     SQMGKLYEPLKKEGFSEDDIEKIYYKNALRVIKEVL"
     gene            complement(12153..12314)
                     /locus_tag="ACGI5H_000943"
     CDS             complement(12153..12314)
                     /locus_tag="ACGI5H_000943"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426006.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9696667.1"
                     /translation="MFILRFADDDDNLSVKDFTSLTDLKKYISENNIDKTWHQIEEVK
                     KVIPNLKEE"
     gene            complement(12324..12821)
                     /locus_tag="ACGI5H_000944"
     CDS             complement(12324..12821)
                     /locus_tag="ACGI5H_000944"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434936.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="SEC-C metal-binding domain-containing protein"
                     /protein_id="HFG9696668.1"
                     /translation="MSLYTEWRNLSDNHESQEAEVKFWEEYLKVEAGIYNEILNNKMD
                     VVEGKVSELAEKFGTTNEFFMGFIDGISESLKEDIVLEEVEADKEVSIKIDWEKLYNN
                     MVTVEAHWLYNLQGWEDILPADQRKEIIKAYKKSKTIVKEAKIGRNDSCPCGSGKKYK
                     KCCGK"
     gene            complement(12936..13646)
                     /locus_tag="ACGI5H_000945"
     CDS             complement(12936..13646)
                     /locus_tag="ACGI5H_000945"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UPF0489 family protein"
                     /protein_id="HFG9696669.1"
                     /translation="MENYEYSGFYIEKPVGNNVFSYDKRENKSIYVPKLINGTLNDVR
                     LGNEVVFNEVDENKEIKAKGLENMVEYVLGNKKIYVFDNHNHAFYFWAKSLLKGEFTK
                     GCKLVHVDQHKDTREPENYDVDVNNLKDVFRYTNEVLNVGSFIKPALKYNIFSELIII
                     DSLYGFDLEVESEFVLDIDLDIFSSDMDYIPFELKFYKIKNLIKKAKVITIATSPYFI
                     NQEYAIKVLKELFNYDII"
     gene            complement(13822..14352)
                     /locus_tag="ACGI5H_000946"
     CDS             complement(13822..14352)
                     /locus_tag="ACGI5H_000946"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434931.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9696670.1"
                     /translation="MDIRALPIRITKEEAIEIAKSGKNSLFSKLILKNKYAHEVRLHY
                     IEFKIITLKIHKTKSIFKNRRYSNDINELKILVNGSTGSGSIVQDFPTYEVVKNVDCN
                     IVQYSDKDERRVKAKANKMAMRLTHRFMGGIPEIEIVKIESIFRPYWVVFFGKVELNR
                     RVSYLPIEADGFVIGM"
     gene            complement(14369..14599)
                     /locus_tag="ACGI5H_000947"
     CDS             complement(14369..14599)
                     /locus_tag="ACGI5H_000947"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434928.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9696671.1"
                     /translation="MSKLVSKVKKDLEIKWLGIDGFLVLLYFLITGFIFYGILTRNDI
                     IVGKIIPYGVMAVVIVIFFDYIYRVLKMTRKK"
     gene            complement(14614..16008)
                     /locus_tag="ACGI5H_000948"
     CDS             complement(14614..16008)
                     /locus_tag="ACGI5H_000948"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892151.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sodium:solute symporter family protein"
                     /protein_id="HFG9696672.1"
                     /translation="MLTFWENGIIVIFAFILLGIGYYFSRNVKDMESYYLGNRSLPWS
                     LIVGTLVASWYGGVGTVGSVEYAAIYGISAWAVWSIAAHIGRMPLALWVGPRIHIRTN
                     ITVPDLLESFYGKHVAIIGAILMFIYCAQLGEITAMGTIGNVAWKIDKELIGLIMVGV
                     VVVLTVLGGLMGVAITDMVLFFCMVFGLTMVMPGQFEQIGGFQGLTEALKDAPQLMHP
                     TKGMSAMKALMLIVYSFGAYSDPTFYQRFSAADSPKVGRRALLTCFSLWICFDMVLTM
                     TGLIVRATYPEMAPAAGYITLVLDTLPQGIRVIFIIGILGSIISTLDSYYLAAGATLA
                     NDIYGRITKKELSQKQLVKFTRIGVCLAAVMGLSVAFRFENVYDACIFVGSIWMGSAF
                     VPIVGGLLGNGRRTSMGGILGMIVGGVTFGYFKIFPVQSFELEPLVIAIPFSFIAWMI
                     GNRIGENLNTQNNL"
     gene            complement(16134..17387)
                     /locus_tag="ACGI5H_000949"
     CDS             complement(16134..17387)
                     /locus_tag="ACGI5H_000949"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892153.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="nitrate/nitrite transporter"
                     /protein_id="HFG9696673.1"
                     /translation="MESKNNVKRFLIIFILAFGTTAMYSLPYMKSSFYDPMQQALALS
                     HTQIGNLLSLYGLVGMVSYFIGGWFADRFSVRKLITFSLIASGILGFYFSTFPSYSMI
                     LLIFVLWGFTTILTFFSASVKVVRMQGSESEQGRIFGFYEGLSGVSGTLISFIGLYFF
                     GKFAEITVGFKYVVWLYSAASIICGILLFFLVEEKKDSGASDEGLSIKSLLKVVTIPK
                     AWLIGLIIFSTYLVFSSLTYLSPYLSEVYVMPMTLVSALSIIRTYVIKMGASPVAGVI
                     TDKVGSSIRVMFVGFILMTVSTAAYLVIPKSTGFIWIAVINMIILSVILFGFRGIYFA
                     SVSESNISLETTGAVVGFASFIGFSPDAFYYTIAGNWLDKYGQTGYTYIFILSVVCAV
                     IGIFATYALNKINKRENKGLNNKIA"
     gene            complement(17438..18592)
                     /locus_tag="ACGI5H_000950"
     CDS             complement(17438..18592)
                     /locus_tag="ACGI5H_000950"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892155.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA];
                     GO_process: GO:0009058 - biosynthetic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="aminotransferase class I/II-fold pyridoxal
                     phosphate-dependent enzyme"
                     /protein_id="HFG9696674.1"
                     /translation="MSNNINQDLETKIIHWGHSADPTTGALATPICQTATFAAKTVEH
                     FEELCMTWGYVYTRECNPTLTELEAKLAMLENAESAISSTSGMGAITSTILALVKSGD
                     HIVSSDGIFSHTKLFMSELLSKFGVEVTFVDAVNPQNVKEAMRPNTKIVYIESPLNPS
                     LDLVDIKTIAEIAHENKSLAIVDSTFGTPIVQRPIDLGADLVIHSLTKFINGHGDTLG
                     GAVAGSKELIDLVRWPSLCCFTGASLPPMSAWMILRGMKTLDMRMKKHCENGLAVAEF
                     LEEEENVELVKYPALKSHPQYELCKTQMNGLGGGVVSFKLKDGISGLTRDQASRRLMN
                     SLELATIATSLGEEHTLVQMNGENLIRIAVGLESSNDIINDFKQAIEKLK"
     gene            complement(19152..19721)
                     /locus_tag="ACGI5H_000951"
     CDS             complement(19152..19721)
                     /locus_tag="ACGI5H_000951"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426023.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HFG9696675.1"
                     /translation="MIIIYGYCRVSTKNQTDNNSLYQQQQEILNKYNDAKIIKETYTG
                     TTTNRPKFEKIISSLKKGDLLVATKLDRLARSTSEGIQLIEGLFAKEVSVHILNIGLL
                     ENTSMGKFFLTTLLAVAELERNMIIERTQLGKEFAKKKKDFKDGRPKKYSNQQIQYAL
                     GLLNSKPYREVVKMTGISKSTLIRAKKSI"
     gene            19924..20151
                     /locus_tag="ACGI5H_000952"
     CDS             19924..20151
                     /locus_tag="ACGI5H_000952"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009906553.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded DNA-binding protein"
                     /protein_id="HFG9696676.1"
                     /translation="MNSLLKEAIDELKNIHCGEVFLLKELFKGYEWNRLEMNIRLKLG
                     KLFLYEVVTNPNLNVEVINKNSAYQQMYKKK"
     gene            complement(20370..21113)
                     /locus_tag="ACGI5H_000953"
     CDS             complement(20370..21113)
                     /locus_tag="ACGI5H_000953"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434912.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3298 domain-containing protein"
                     /protein_id="HFG9696677.1"
                     /translation="MENYQSTNTCTYNILYVQFNEDFERSKYFSYDVKYPVIYNIRNQ
                     STYVNPVILNNINNAVRMTVNNFKNGLQEEEREYNNAASQNSLPKQSYWVSTSYAVTF
                     NKNYVLSMILNLMGFANNYGPKYNTLNNYNIDLTTGKELLLNDIFRDGVDYINIITDY
                     IKSQINENREMYYSNVELVIPEDQAFYLTDNGIIIYFGVDEIAPESFGIPKFELKFSD
                     FGNFINLRFYCISPDIYVQSRGRAKHFMG"
     gene            21281..22153
                     /locus_tag="ACGI5H_000954"
     CDS             21281..22153
                     /locus_tag="ACGI5H_000954"
                     /EC_number="2.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422265.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008168 - methyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HFG9696678.1"
                     /translation="MLLLADKWKDYELIDMGNGEKLERWGSYVLRRPDPQVVWPMESE
                     WALWKNPHGHYHRSNKGGGQWEHKKRYPEQWTINYKNLKFHIKPTGFKHTGLFPEQAA
                     NWDWMIEKIKKANRPIKVLNLFAYTGGATVACASAGAEVCHVDAAKGMVNWAKENIEL
                     SGLKNQTVRFIVDDVVKFVEREIRRGKKYDAIIMDPPSYGRGPKGEVWQIEEKLYSFV
                     DLCMGVLSDNPLFFLINSYTTGFSPIVLENVLSTTIGKKTNTGDIYGGELGIPASRDG
                     KILPCGIFGRWEKK"
     gene            22153..22818
                     /locus_tag="ACGI5H_000955"
     CDS             22153..22818
                     /locus_tag="ACGI5H_000955"
                     /EC_number="5.4.99.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892161.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0009982 - pseudouridine synthase activity
                     [Evidence IEA];
                     GO_process: GO:0001522 - pseudouridine synthesis [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="RluA family pseudouridine synthase"
                     /protein_id="HFG9696679.1"
                     /translation="MIKVIYEDNHLLVVEKPVNILSQGDNTNDKDMVNLLKDYIKKKY
                     NKPGNVYIGLIHRLDRPVGGVMVFAKTSKAASRLSEQVRSKTFKKTYLAVVHGKIKSN
                     SDILKDFLYKNKKTNMVTVVKKSHKDAKEAELNYNVLDFKENLSLVQVNLKTGRSHQI
                     RVQFASRKHPLYGDQRYGKEINKIGQQISLWSNKIEICHPTTKEKMEFTCHPPDKYPW
                     NIF"
     gene            22839..23696
                     /locus_tag="ACGI5H_000956"
     CDS             22839..23696
                     /locus_tag="ACGI5H_000956"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892163.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HFG9696680.1"
                     /translation="MSKKFSIGEMSKLHKISIQTLRYYDQIDLFKPVHVDQESNYRYY
                     SIDQFSQLDIIKYLKYLGMPLKEIKSKLDENNEEILKLLTNKINIVDEKIKELELIKK
                     VLSTKKETMEKGMKVDEVGKIVRKHIPRRSILSIEYEEGLSSEETMELSRRQIANILE
                     DNISVFYGGVSGLVSIDKFLKEDKVIYDNSFVTVERDLFDIKSQKHITEISSGDFICM
                     TYKGPYKENYTAFKKLVDYVEYKRIPIENYIYEIPIIDPLSTNNEEELLTEIQIQVKK
                     REIDLRCLV"
     gene            complement(23852..26398)
                     /locus_tag="ACGI5H_000957"
     CDS             complement(23852..26398)
                     /locus_tag="ACGI5H_000957"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434900.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HFG9696681.1"
                     /translation="MNIFNKVALQGLKKNRTRTLVTIIGVVLSAAMITAVTTFGVSLM
                     NYMINGAIIKYGDWHVQFLDVDSSFVQEQRVNDEVANTATFENIGYATLEGNRNPDKP
                     YLFIAGFSKEAFDTLPITLISGRLPENSREILVSSKVATDGGVKFAVGDTISLDVGKR
                     MSENEKLGQSDPYTAGSEVFVPQDKKTYTVVGICRKPVFEESSAPGYTLITKEDKQVK
                     TDSLSLFVTLKNPHQIRSYTSSTKDHASIFNDNVLRFIGVSDNNLFNMFLYSVGGIVL
                     AIIMLGSIFLIYNSFNMSLNERTHQFGILSSVGATAKQLRNSVLFEGICIGAIGIPIG
                     VAIGIVSIGLVISVISKNFANILYVNVPLTLTLSIPAIIVAAVVSMVTILISAYIPAR
                     KAANTPVMECIRQTNEVKIESKSVKTSKLTQRVYGLEGVLAMKNFKRNKKRYRSIVLS
                     LVLSIVLFISTSALVADLKQMSNQRSEVTDQDIIFSTQGMKDNEMLKLYDKLKTANGV
                     YEGLYQKLMTYSCVAKVSELTDDYLNYEGSHSMSEMLELPVDMQFLDDRTYLNIIKSL
                     GLPAEEYTGQNAKLIAVSMVTKDNNIIDIFNSSSMNVSLTPETNGKLEIPERQNVNIS
                     FVKVVPPDSPPGIRSSDVKKASFRVLAPYSAKDKFEIPGVSTGIESLSFQSKNPTQSV
                     AEMEQIIESEGVTNEYNLYNMYGMMDENRNYIFIANVFAYTFIIMISLISIANVFNTI
                     STNIKLRRRELAMLRSVGMSEHDFQKMMNFECAFYGMRALFFGLPIAVISSWLIHKVM
                     VTDDIDFVIPWFSIGISIFSVLFIVFITMLYTINKIKKENIIDALRDDMA"
     gene            complement(26398..27084)
                     /locus_tag="ACGI5H_000958"
     CDS             complement(26398..27084)
                     /locus_tag="ACGI5H_000958"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422273.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HFG9696682.1"
                     /translation="MAFLKIEDLCKVYGKNENKVTALDHVSLTIEKGEFTAIIGSSGS
                     GKSTLLHSIAGVDVPTSGKIYLEGQDVYGQSNEKLAIFRRRQVGLIYQFHNLIPTLNV
                     VENITLPILMDKRKVNQERLNDLLELLGLKERKTHLPNQLSGGQQQRVAIGRALMNAP
                     AVMLADEPTGSLDSKNGQEIIQLLKESHSKYHQTLIIVTHDENIALQADRIICISDGK
                     VVRDERKVNR"
     gene            complement(27167..28156)
                     /locus_tag="ACGI5H_000959"
     CDS             complement(27167..28156)
                     /locus_tag="ACGI5H_000959"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434897.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing sensor histidine kinase"
                     /protein_id="HFG9696683.1"
                     /translation="MFRNREFRKFAILFLLITILTVALGFAISIMTGILSIVSATTFG
                     IAFFVFTKNRYKSIAQISEQINLVLHNANHLYIAESDEGELSILQSEITKMTLRIREQ
                     NYALKKEKEHLADSLADIAHQLRTPLTSVTLILSLLENTSDEDERKELIRETEELLIR
                     MDWLITSLLKLSRLDAGIVVFQKEQIDVNNLISSALHQLLIPMELHNITLHIDIPKGV
                     RILGDLNWLSEAIQNIFKNCMESVGDNGKIDIICEDNFLFTQLTIHDNGAGFKKEDLP
                     CLFNRFYRGKNSSTAGYGIGLALCKTIIMRQGGTITAQNHPQGGAIFVIRFPK"
     gene            complement(28143..28829)
                     /locus_tag="ACGI5H_000960"
     CDS             complement(28143..28829)
                     /locus_tag="ACGI5H_000960"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434895.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000156 - phosphorelay response regulator
                     activity [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HFG9696684.1"
                     /translation="MKRIFLVEDDKAIAKNLILLLNSEGFIVTHVSTRSEALVEIAKN
                     KFDLALIDISLPDGNGFTICTEIKEKQDIPVIFLTASGDESSVVTGLNMGADDYITKP
                     FRPRELIARIRTALRKSGRFGSTFEICGLYVDTATGVVKKNGNEVFLSALEYRLLLVF
                     ISNPKSIITRVRLLDELWDAAGEFVNDNTLTVYIKRLREKIEDDPSSPQIILTVRGTG
                     YRLGGSYVSK"
     gene            complement(28826..28948)
                     /locus_tag="ACGI5H_000961"
     CDS             complement(28826..28948)
                     /locus_tag="ACGI5H_000961"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9696685.1"
                     /translation="MDYIRTKETTENCVMISKIVVYYCSAGIYKTNKIKEDESK"
     gene            complement(29329..32535)
                     /gene="carB"
                     /locus_tag="ACGI5H_000962"
     CDS             complement(29329..32535)
                     /gene="carB"
                     /locus_tag="ACGI5H_000962"
                     /EC_number="6.3.5.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011862003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0008152 - metabolic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="carbamoyl-phosphate synthase large subunit"
                     /protein_id="HFG9696686.1"
                     /translation="MPKLDSIKKTLVLGSGPIIIGQAAEFDYSGTQACQALKEEGIEV
                     VLVNSNPATIMTDKEIADKIYIEPLTIEFIEKIIEKERPDSLLAGMGGQTGLNLAVEL
                     HDAGILDKYNVKVIGTSIESIKKGEDRDLFREVMKEINQPVIVSDIVTNLEAGLEFAN
                     KIGYPVVVRPAYTLGGTGGGIADTEEELREILSHGLQLSPVGQVLLEKSIKGWKEIEY
                     EVMRDGNGNCITVCNMENVDPVGVHTGDSIVVAPSQTLSDEEYQLLRKASIDIINAIE
                     VQGGCNVQIALNPHSLEYAIIEINPRVSRSSALASKATGYPIAKVAAKIALGYTLDEI
                     ENAVTKKTYACFEPTLDYVVVKIPKWPFDKFRHANRKLGTKMMATGEIMSIGSNFEAA
                     ILKGIRSLETGKYSLVHAPSEGRTLEELKARVVVPDDERLFDLAEMIRRGYKVEMISE
                     ITGVDKWFINKFKWIVEQEEKLKVLKIEDLDKEYLHELKKKGFSDKGISDLMKISPEK
                     LYELRSLYNIQPVYKMVDTCGGEFEALSPYYYSTYEQYDEVVVSDKRKVVVLGSGPIR
                     IGQGIEFDYCSVHCVKSLRKMGIETIIVNNNPETVSTDFDTSDKLYFEPLTEEEVLNI
                     IEKEKPEGVILQFGGQTAIKLAKFLHEKNIPILGTDFRDIDAAEDREKFDDLLERLDI
                     NRPKGKGVWTTNEGVEIAKELGYPVLVRPSYVLGGQGMEITYNEEKLIQYLDDAFDRD
                     HKNPVLIDKYLTGREIEVDAICDKEDILIPGIMEHLERAGVHSGDSTTMYPSQNISDE
                     IKEKIVEYTKKIALDLNVLGMVNIQFIEFQNELYIIEVNPRASRTVPYISKVSGVPIV
                     DLATKCMLGAKLKDLGYGTGVYKEPKLVSVKVPVFSMSKLSKVEVSLGPEMKSTGEVL
                     GVGENLEEALYKGFLAAGRHMSDERGVVLATVNNHDKDEFIEIAKDMKELGYTFVATE
                     GTAKSLRENGIEADIVNRIEEPRPNILDAIRNKQVDIVINTPTKGNDSTRDGFKMRRT
                     AIEFSTEIMTSLDTLKALVEVKKKHLNKDKLKVYNIAE"
     gene            complement(32728..33777)
                     /gene="carA"
                     /locus_tag="ACGI5H_000963"
     CDS             complement(32728..33777)
                     /gene="carA"
                     /locus_tag="ACGI5H_000963"
                     /EC_number="6.3.5.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002845470.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004088 - carbamoyl-phosphate synthase
                     (glutamine-hydrolyzing) activity [Evidence IEA];
                     GO_process: GO:0006207 - 'de novo' pyrimidine nucleobase
                     biosynthetic process [Evidence IEA];
                     GO_process: GO:0006541 - glutamine metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine-hydrolyzing carbamoyl-phosphate
                     synthase small subunit"
                     /protein_id="HFG9696687.1"
                     /translation="MKARLILEDGTVFIGKAFGYLEESVGEVVFNTSMIGYGEVLTDP
                     SYYGQIVTMTYPLVGNYGINLSSAESEKVQVKGFIVREKSDSPSNFRCEIDIDQYLKQ
                     NKVIGLEGIDTRALTKILRNNGTMKGIITLEDSKLEDVKHKLDKFSNTEAVRTVTRKE
                     VEHIKGNGPKVAVMDFGVKRNILRSFIARGCDITIFPATTSPEDVLSINPDLIFLSNG
                     PGDPEDLEDVIENIKALIGKKPIVGICLGHQLLALALGGKTAKLKFGHRGGNHPVKDL
                     EEGKVFITSQNHGYYVSEVPEQMKVTHINLNDNTVEGMRHEKLDVYSVQYHPEACPGP
                     KDNDYIFDKFLELVK"
     gene            complement(34034..37240)
                     /gene="carB"
                     /locus_tag="ACGI5H_000964"
     CDS             complement(34034..37240)
                     /gene="carB"
                     /locus_tag="ACGI5H_000964"
                     /EC_number="6.3.5.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011862003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0008152 - metabolic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="carbamoyl-phosphate synthase large subunit"
                     /protein_id="HFG9696688.1"
                     /translation="MPKLDSIKKTLVLGSGPIIIGQAAEFDYSGTQACQSLKEEGIEV
                     VLINSNPATIMTDKEVADKIYIEPLTIEFIEKIIEKERPDSLLAGMGGQTGLNLAVEL
                     YEKGILDKYGVKIIGTSVESIKKGEDRDIFREVMKEINQPVIVSDIVTDLQAGLDYAL
                     TIGYPVVVRPAYTLGGTGGGIADNEEELREILSHGLQLSPVGQVLIEKSIKGWKEIEY
                     EVIRDSKGNCIVVCNMENIDPVGVHTGDSIVVAPTQTLSNKECAMLKKASLDILNAVE
                     VQGGCNVQFALNPHSFEYAVIEINPRVSRSSALASKATGYPIAKVSSKIALGYTLDEI
                     ENAVTKKTYACFEPTIDYVVAKIPKWPFDKFKKANRKLGTKMMATGEIMSIGSNFEAA
                     ILKGIRSLETGKYSLVHTPSEERSIEELKKRVVVPDDERLFDLAEMIRRGYKVEMIEQ
                     ITGIDKWFINKFKWIVEQEEKLKVMKIEDLTKDYLLELKKKGFSDKGISDLMKISPEK
                     LYELRSLYNIKPAYKMVDTCAGEIDAISPYYYSTYEQYDEVVVSDKKKVIVLGSGPIR
                     IGQGIEFDYCSVHCVKSLRKMDIETIIINNNPETVSTDFDTSDKLYFEPLTEEEVLSI
                     IEKEKPEGVILQFGGQTAIKLAKFLHEKNIPILGTDFDDIDAAEDREKFDDLLERLDI
                     NRPKGKGVWSLNEGIEVANELGYPVLVRPSYVLGGQGMEITYNEEKLSQYLQDAFDRD
                     HKNPVLIDKYLTGREIEVDAICDKEDILIPGIMEHLERAGVHSGDSTTMYPSQNISDE
                     IKEKIVEYTKKIALDLNVLGMVNIQFIEFQNELYIIEVNPRASRTVPYISKVSGVPIV
                     DLATKCMLGAKLKDLGYGTGVYKEPKLVSVKVPVFSMSKLSKVEVSLGPEMKSTGEVL
                     GVGENLEEALYKGFLAAGRHMSDERGVVLATVNNHDKDEFIEIAKDMKELGYTFVATE
                     GTANSLRENGIEADIVNRVEESRPNILDAIRNKQVDIVINTPTKGNDSTRDGFKIRRT
                     AIEFSTEIMTSLDTLKALVEVKKKHLNKDELKVYNIAE"
     gene            complement(37293..38336)
                     /gene="carA"
                     /locus_tag="ACGI5H_000965"
     CDS             complement(37293..38336)
                     /gene="carA"
                     /locus_tag="ACGI5H_000965"
                     /EC_number="6.3.5.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011862004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004088 - carbamoyl-phosphate synthase
                     (glutamine-hydrolyzing) activity [Evidence IEA];
                     GO_process: GO:0006207 - 'de novo' pyrimidine nucleobase
                     biosynthetic process [Evidence IEA];
                     GO_process: GO:0006541 - glutamine metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine-hydrolyzing carbamoyl-phosphate
                     synthase small subunit"
                     /protein_id="HFG9696689.1"
                     /translation="MKGKLILEDGTVFEGKAFGYLKEAIGEVVFNTSMAGYGELLTDA
                     TYYGQIVTMTYPLIGNYGINLEDVESNKVQVKGLIVREKSDNPNNFRCEMDIDTYLKQ
                     NKVIGLEGIDTRALTKIIRNNGTKRGIITLENVSLQDVQSKLEEHCNKDSVKNVTRKE
                     IENIKGTGAKVVVIDFGVKNSVLESLKACNCDITIVPAMTTVEEILNINPDLILLSNG
                     PGNPEDINDIVENIKKLIGKKPLTGIGLGHQILALALGGKTSKLVFGHRGGNHPVKCL
                     ETGKVFITSQNHGYNVSEMPENTEVTHINLNDNTIEGMRHKELPIYSVQYIPEYTTKE
                     DLDCIFNKFLALI"
     gene            complement(38362..39078)
                     /gene="pyrF"
                     /locus_tag="ACGI5H_000966"
     CDS             complement(38362..39078)
                     /gene="pyrF"
                     /locus_tag="ACGI5H_000966"
                     /EC_number="4.1.1.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004590 - orotidine-5'-phosphate
                     decarboxylase activity [Evidence IEA];
                     GO_process: GO:0006207 - 'de novo' pyrimidine nucleobase
                     biosynthetic process [Evidence IEA];
                     GO_process: GO:0044205 - 'de novo' UMP biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="orotidine-5'-phosphate decarboxylase"
                     /protein_id="HFG9696690.1"
                     /translation="MINGKEKLIVAIDTDEFDKAKELIDRLEDSVDIFKVGLEQYVAT
                     KGKTIDYLKEKGKKIFLDLKFHDIPNTMKSAVKAAVRDNVWLMTIHVSDMEGMRQCAL
                     IAREEAERLNIEKPLVVGVTVLTSLSNQDLQDIGCNMTTEELAIKRAKLAKESGIDGV
                     VCSAQEVDKIVEACGTDFITVCPGIRPKSAEVGDQKRVVTPSDAIKKGAHYLVVGRPI
                     TKAENPRESAINIVREIENA"
     gene            complement(39454..40089)
                     /locus_tag="ACGI5H_000967"
     CDS             complement(39454..40089)
                     /locus_tag="ACGI5H_000967"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422299.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1847 domain-containing protein"
                     /protein_id="HFG9696691.1"
                     /translation="MYKCGKCNLRGCSNGNMDKLMKICPTREIELQQKAKQLYEEEEN
                     RKIAYNAGLVEAEGYCQYTRLKEIIEFAKKCGYKKIGIAFCIGLKREMQTVQKIFEHH
                     GFEVFSVICKNGAMPKSTIGLEASQTISKCSDEVMCNPIGQALFLNEAKVDLNVILGL
                     CVGHDTLAMKYMEAPITTLVVKDRVTGHNPVAAIYNAESYFEKKLFDKDEE"
     gene            complement(40113..41027)
                     /locus_tag="ACGI5H_000968"
     CDS             complement(40113..41027)
                     /locus_tag="ACGI5H_000968"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892179.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nitroreductase family protein"
                     /protein_id="HFG9696692.1"
                     /translation="MELYEAIFYRKSVRNFSSKKIKKPLMEEIKRSCKNLEYLNEDLN
                     IKAHVVDRGHIIHFLMGKECKVKAPHYIVVTSDKGEDYLQNIGFATEGVVLRLTTLGI
                     ATCWLEGNLKREDILEFVDIGNKNFEEDEEDDLDYLAGIKTEEDDENKIENPYIIIAF
                     GYPAKNEELFRTRYARPDRKPVKDMINKINRNRKWKDILELTRRAPSVKNSQPWYFHK
                     DERGLHLFEKRPKKHCEDMNKVSLGVALRHFDIACIKNKIDVSYEKLPIRNKIGKSYF
                     ITVVEHVKPEEETQEENVTLEKEESQDE"
     gene            41628..42857
                     /locus_tag="ACGI5H_000969"
     CDS             41628..42857
                     /locus_tag="ACGI5H_000969"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429165.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase"
                     /protein_id="HFG9696693.1"
                     /translation="MNLNRNLEKYAELAIKVGVNIQPGQILLIKSPIECADFARNALK
                     EAYKCGAKNVYIEWSDEESTLIKYLYAPDEAFHEFPKWTAEQYVDIAKEGGAFLSVYA
                     QNPDLLKDVDPERVANFQKASGKALKEWRSYTLTDKCKWSIVSVPTKDWAKKVFPNLS
                     EDKAIEKLWDAIFKCSRVDGQDPIKAWEEHNENLKSKMDFLNKNNFKTLKYKSSKTDL
                     TLDLPKGHVWLSGASKDPNGISFNPNIPTEEIFGMPHKFKVNGTVYSTKPLVYGGNII
                     DNFFLTFKDGKIIDFSAEKGLDTLEKLIETDEGSHYLGEVALVPYNSPISNTDIIFYN
                     TLYDENASCHFAIGSAYKTCLEGGNNLKDEELDEHGVNDSLTHVDFMIGSADMDIIGE
                     TYDGKQIQIFKNGNWAF"
     gene            complement(43062..45443)
                     /locus_tag="ACGI5H_000970"
     CDS             complement(43062..45443)
                     /locus_tag="ACGI5H_000970"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729141.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="homocysteine S-methyltransferase family protein"
                     /protein_id="HFG9696694.1"
                     /translation="MEIRQYLKNNILIFDGAMGTMLQQKGLKLGENPEVFGLQNPDKL
                     IEIHTAYLEAGSNVILTNTFGCNELKLDSKYTVEEVIDNAVLVARKAIENVDNTKPRY
                     VALDIGPIGEMLEPMGTLSFDKAYEIFKRQVLQGVKSGVDVIVIETMMDLYEAKVAVL
                     AAKENSDLPIFCTMTFDEGGRSFTGCMPECMVATIEGLGVDAIGVNCSLGPKQLLPIV
                     EKIASRATVPVMVQANAGLPNIVDGEAIYDVDAKEFFEGVKKFVEVGATIIGGCCGTN
                     PSFIKEISENINSVTKGCIEKIDKCVVCSPSKFVEVQSPTVVGERLNPTGRKSLQEAL
                     KNENVDYAINLGLEQVNAGAQILGVNVGLPEIDEKKLMPKLIREIQAVVDTPLQVDSS
                     NVEALEQGLRYYNGRTIVNSVNGKEESLESILPIVKKYGSCVVGLTLDEKGIPKKAEE
                     RFEIAKRIVNRAVSYGIKPKDIFIDCLSLTVSAQQEEAIETIKAITMVKTLGVKTILG
                     VSNISFGLPNRKALNASFLTLALGAGLDLAIINPNEYSMMEAINSFKILNNTDKGCIN
                     YINQYSNINNSKKSDSSTKIDKDLPLDILVERGLKDEAKNVTLNLLKEKDENYILDEI
                     LIPALDKVGKRYDSGDIFLPQLIQSAETVKVSLNTIKETLLSKSSNNVSKGKIIVATV
                     KGDIHDIGKNIVKIMLENYGYEVIDLGKDVPIEEVVEVAKKRNIKLVGLSALMTTTVQ
                     SMKDTIQALRDNEINAKVFVGGAVLTEEYAEEMGADYYSKDAKSAVEIAKLNF"
     gene            complement(45415..46140)
                     /locus_tag="ACGI5H_000971"
     CDS             complement(45415..46140)
                     /locus_tag="ACGI5H_000971"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422307.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008705 - methionine synthase activity
                     [Evidence IEA];
                     GO_process: GO:0009086 - methionine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="vitamin B12 dependent-methionine synthase
                     activation domain-containing protein"
                     /protein_id="HFG9696695.1"
                     /translation="MENNLIGREDISINQSEVLRYLQYRGQEIDKDLKYTIDECVAIT
                     KNKINPRYLSRIYPIKINKDNVVELEGTNLTLESKDVYELLKECNECVIMAATIGIDI
                     EKEIRRHSYSNLTKGLIIDSCGTTAIEEVCDIVQNNLEKVFLKQDKFITMRYSPGYGD
                     LPIEKNIDILNVLNAQKQIGLTITSNGIMIPRKSVVAIIGISNTRINKSKKEKSCENC
                     KNYRNCTYRKGANSCGNKTISEK"
     gene            complement(46130..46585)
                     /locus_tag="ACGI5H_000972"
     CDS             complement(46130..46585)
                     /locus_tag="ACGI5H_000972"
                     /EC_number="4.4.1.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429171.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S-ribosylhomocysteine lyase"
                     /protein_id="HFG9696696.1"
                     /translation="MEKVESFKLDHTKVKAPFVRKCSVLDGVKGDKVTKFDLRFLQPN
                     VESFGTAAMHGLEHLLATYLRDTLDGVIDLSPMGCRTGFYLILWGDVDAKTVKIGLEE
                     ALKKVLESDKMPAATAIECGNYRDLSLFGAKEYAKDVLDKGFSLNIYGE"
     gene            complement(46867..48048)
                     /locus_tag="ACGI5H_000973"
     CDS             complement(46867..48048)
                     /locus_tag="ACGI5H_000973"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729142.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HFG9696697.1"
                     /translation="MKNKSLLNHMFRPILDLIISCALTSMLILTSMYIIKSLYVNSDM
                     SVVNQLVYQARDFRSLIGYDLFYPFLFTITSLAIYSMISYKRNKQIVDFIRKTNRKNQ
                     KLEIIKSAVNLMDEGNLEKSIDIEYDLDILKDKEKDDIDELAHKINNIVHQLRNITIE
                     ERQAQQTKTDLITNVSHDLRTPLTSIMGYLGVIEEGKYKDEVQMMYYVDIAYEKSKNL
                     NVLINDLFELTKMQNNTIKLNKIEINLVELLSQVVSQFEIYFKQEFMVSRINFNEEKL
                     IVKADPNKLVRAFENLITNAVKYGKDGHYVDIVTEKKEDMAVVKVINYGEPIPVLDLP
                     NIFDRFYRVEKSRNRNVGGSGLGLAITKNIVNLHDGEITVSSDKYQTVFEVQLPIIQS
                     A"
     gene            complement(48038..48730)
                     /locus_tag="ACGI5H_000974"
     CDS             complement(48038..48730)
                     /locus_tag="ACGI5H_000974"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903832.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000156 - phosphorelay response regulator
                     activity [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HFG9696698.1"
                     /translation="MNNTVLVVDDEKEIRDLIEIYLLNSGYNVIKAEDGKEALDILKK
                     ENIHLMILDIMMPKMDGIEVCRKVRESLNIPILMLSAKSEDMDKIQGIMTGADDYLTK
                     PFNPLELTVRVKSLIRRAYYFSGANNEDKDVIKVGVVIIDKEKHSVTVAGNEIILTSR
                     EFDILYLLANNKGRVYSTEEIFEKVWKEKYYQSNNTVMVHMSRIRDKIEKYTDGEKII
                     HTVWGVGYKIEK"
     gene            complement(48864..49580)
                     /locus_tag="ACGI5H_000975"
     CDS             complement(48864..49580)
                     /locus_tag="ACGI5H_000975"
                     /EC_number="3.4.17.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422315.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008233 - peptidase activity [Evidence
                     IEA];
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="M15 family metallopeptidase"
                     /protein_id="HFG9696699.1"
                     /translation="MKKFKLIGAIILVVFISVFISKDRLLKKDKDPIVAAQHDSEQDV
                     EANSQNKNHSNSISNILLVNKTNGISKNYTPENITKVNIPFVEEATEEEKQMAGEPAK
                     AVEDLVKQANSEGIQFLGSSAYRSYDTQLDTYTRRVKSQGREKADAYVAKPGYSEHQT
                     GLCIDLTNPERWFVGSTKEAKWLAENAHKFGFIIRYPEGKEDITGTAYEPWHIRYVGK
                     DAAEEIYSKGLTLEEYLQNK"
     gene            49705..50439
                     /locus_tag="ACGI5H_000976"
     CDS             49705..50439
                     /locus_tag="ACGI5H_000976"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894078.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA 2-thiocytidine(32) synthetase TtcA"
                     /protein_id="HFG9696700.1"
                     /translation="MSIQKLLSKARKAIQDFDMIQENDKIAVGLSGGKDSLTLLHILK
                     SYQRFSPQNFELIAITLNTGGVDNSPLDKLCKEINVPFYEFQTDIKEIVFDIRQEKNP
                     CALCANLRRGALNDNAKKLGCNKVALGHHKDDAIETFLMSMFYEGRVNCFSPKTYLDR
                     QDLTVIRPMVYIEEYMTKKISKDSNYPIITNPCPANGHTRREYIKNLIANLNKEMPDF
                     KRNVFGALNNSEKLFIWDKEKIKNFK"
     gene            complement(50724..51479)
                     /locus_tag="ACGI5H_000977"
     CDS             complement(50724..51479)
                     /locus_tag="ACGI5H_000977"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435801.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metallophosphoesterase"
                     /protein_id="HFG9696701.1"
                     /translation="MKKYNISENGALIKNDSIESKSESVKVVQISDTQIGSFYSTKNL
                     KKVANKINTLNPDIIVFTGDLIDYSNKNPSVDEITTILSSMNARLGKFSVFGNHDYMY
                     KLPRYYRQIMKNSNFNLLVNENKKIKLKDDKYINILGVDEILNGNPNIKYLESQIDNK
                     SFNLLLAHEPDLVDMLSKDTMNLVLSGHSHGGQIRLPIKGALVTPPYGRKYTKGFYDI
                     NGNHLYVSSGLGSTKLPFRFFNIPEIIEFNIII"
     gene            complement(51601..52539)
                     /locus_tag="ACGI5H_000978"
     CDS             complement(51601..52539)
                     /locus_tag="ACGI5H_000978"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429183.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HFG9696702.1"
                     /translation="MKSILIMGGSDFIGSALAKRLIKCGYQIDILTNGKKEIDYNGFK
                     EHLICDRKVRKDMENIITGRKYDYIYDMTAYTKEDVSNLIDFISMDNLKKYIVLSAGA
                     VYKDSGRNIKEENEKGENENWGKYGLNKKEAEDFIINSPIPYIIIRPTYIYGENNNLY
                     REYYFFEKIEKNEKIPVPKGKQVSNQFIYIGDLVKVLESIMKNPHVREAYNVTNPQLI
                     SWDDLIYTCGEIIGKEPIIKYVDMEKVEFRERTYFPFRNIDFNLDINKLIEHGLYIPN
                     VLLKEGLTATYKWFSANKPKMHDRKMNKVESVMQIV"
     gene            complement(52642..53292)
                     /locus_tag="ACGI5H_000979"
     CDS             complement(52642..53292)
                     /locus_tag="ACGI5H_000979"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422319.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family hydrolase"
                     /protein_id="HFG9696703.1"
                     /translation="MKKNYEIVLFDLDGTLTDPKEGITKSIQYSLNSFGIKEDLENLD
                     QFIGPPLHDTFKEYYKFEDKKAKEAVEKYREYFADKGIFENKIYENMKEILEMLYKNG
                     KILLVATSKPTVFAETILRYFDIDRYFKYIAGSNLDGTRVNKNEVIQYVLDLCNVKDK
                     DKVIMVGDRKYDIIGAKKIGIDSIGVLYGYGSFEEISESEPTYIVENVESIKDILL"
     gene            complement(53441..53629)
                     /locus_tag="ACGI5H_000980"
     CDS             complement(53441..53629)
                     /locus_tag="ACGI5H_000980"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422320.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005506 - iron ion binding [Evidence IEA];
                     GO_function: GO:0009055 - electron transfer activity
                     [Evidence IEA];
                     GO_function: GO:0051539 - 4 iron, 4 sulfur cluster binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ferredoxin"
                     /protein_id="HFG9696704.1"
                     /translation="MKAFVDKDVCVACGACIGTCPDVFSMSDEGHSVAIEGEIPADLQ
                     DLCKEAEEGCPVSAITVK"
     gene            complement(53736..54920)
                     /locus_tag="ACGI5H_000981"
     CDS             complement(53736..54920)
                     /locus_tag="ACGI5H_000981"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="amidohydrolase family protein"
                     /protein_id="HFG9696705.1"
                     /translation="MKNLLIRNGTIISPTDGIKFEKRDILVLHGKIYAIGLNLKEKIR
                     KEKLLTNKEFEIINADNMYISPGFIDVHTHCYKRKLPTGMDSDSIGIEKGSTVIFDAG
                     TAGPSNYYDFKKKYMDECKTEVYSFLNVTNEGLNILNESTYLDVINFDKVESIVEKNI
                     EKIKGIKVKASKFQSNESGIDIIKKSKQVAKKLNLPLVVYIGEYPSYIDEVMNILGKG
                     DVVTPVYGNSTNGILKESGTLRKSVINAKNRGVLFDVCHGVDQFDFKVFKKAIKQGLE
                     PDLISTDMHIKNMKDVNYSLLNVINKIMELGISLEKCIEKVTEYPTKIFDLHGNKGRI
                     KIGGEGDFTIFTMEECNDIIKDYNNNELVLNKKLRLQYTVKSWMKSSEVYRHGYENTI
                     IN"
     gene            complement(55062..55979)
                     /locus_tag="ACGI5H_000982"
     CDS             complement(55062..55979)
                     /locus_tag="ACGI5H_000982"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429188.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SufD family Fe-S cluster assembly protein"
                     /protein_id="HFG9696706.1"
                     /translation="MNKIDLNLLEKVAELRGTPLGAYNIRKNGQGVERHSTENVTIIP
                     KTDKPGIDIIVKPNTKGENVHIPVIVTEAGVQDMVYNDFEIGENADVVIIAGCGIHNC
                     GCDDSEHNGIHRFFLRKGARLKYVEKHYGEGDGEGKRILNPVTIVNMDEDSYCEMETI
                     QIKGVDSTKREMDANLGKGAKIVVFEKLLTHGNQVAESNMKVILEGENSSAQVVSRTV
                     GQDNSKQKFNPCVIGDSLCSAHVQCDSIIMGNSQISAIPEIAANHPDALLVHEAAIGK
                     IAGDQILKMMTLGLTEEEAEQQILNCFLK"
     gene            complement(56001..56729)
                     /locus_tag="ACGI5H_000983"
     CDS             complement(56001..56729)
                     /locus_tag="ACGI5H_000983"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429190.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HFG9696707.1"
                     /translation="MLEIKNLSFNVESNNEELGIINDVSLSFERGKLIVITGPNGGGK
                     STIAKLIMGIEKATSGQIILDGEDITNLSITERAKKGIGYAFQQPPRIKGMTVENLLT
                     LAHGKPLSTDVCCQYLTDVGLCSKDYLNREVDNSLSGGEMKRIEIATLFARDLKVSIF
                     DEPEAGIDLWSFGKLNESFKKIHEESNQTIIIISHQERILELADEIIVLQDGSVKSHG
                     TKEAILPEIMCQVNSSCELMKDMN"
     gene            complement(56925..57125)
                     /locus_tag="ACGI5H_000984"
     CDS             complement(56925..57125)
                     /locus_tag="ACGI5H_000984"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420681.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9696708.1"
                     /translation="MFKKMAVLKDIATKIGRKKAYELLEMVEGNDAFVAEVKIKKNGI
                     ESKKEEIMLKDNQKIILEYIEG"
     gene            complement(57250..57630)
                     /locus_tag="ACGI5H_000985"
     CDS             complement(57250..57630)
                     /locus_tag="ACGI5H_000985"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729145.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HFG9696709.1"
                     /translation="MINKIGKITLYVNNQEDAKLFWTEKLNFVVTYEKEMGPNMKWVE
                     VAPSKNEFTTFVLYDKNLMMKQNKEINVSHPSIILSTRDINGTYEQMANNEVEVGELM
                     EMPYGRMFSFKDQDGNDYLVREDK"
     gene            complement(57903..59261)
                     /locus_tag="ACGI5H_000986"
     CDS             complement(57903..59261)
                     /locus_tag="ACGI5H_000986"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729146.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0042910 - xenobiotic transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0006855 - xenobiotic transmembrane
                     transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MATE family efflux transporter"
                     /protein_id="HFG9696710.1"
                     /translation="MFIRKNVIKLAIPIMIEQTFVMLLGVFNTMMAGHIGEEAVSAVG
                     MVDSINNIFISVFAALSVGATVVVAQQIGKKDSEKVNETIKQALVSGVILSFTITILM
                     WVFRTGVINLFYGSAEELVKSNAKLYIEFTLFTYPFIATQQIANGILRGCGDVKKPMY
                     VTMFMNIVNVTLGYILIYGIDLNPLGINLQTPSYGITGAAISIAIARIIGCIVIIRAL
                     FKGNEFISMGKIFPFKIDVETQKSIFNIGIPAGVEQLLFNAGKLIVQVFIVTMGTSAI
                     ASNAIGMSIASIINVIGNALALSATTLVGQYIGRGDIKGAKSTLLYLTKFATICLFIV
                     GAIFIPIAPWISSMYTQNASVIDISTQLIRSDCLAMVIWPISFVLSAGLKGAGDTRYT
                     MMTAVIGMWIFRIFTGYVLGVVLEFGVLGIWIGMYTDWLVRGTLYCLRLRGTKWLKHK
                     VA"
     gene            59709..60161
                     /locus_tag="ACGI5H_000987"
     CDS             59709..60161
                     /locus_tag="ACGI5H_000987"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892191.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="staygreen family protein"
                     /protein_id="HFG9696711.1"
                     /translation="MVNLNANNLNVNMVYPISSTAPIRFRRYTVSYLENMENIYLTIA
                     TYFDTLGLGTMNIDKVYGQWAWFTDNIYDLNLFVFVGNYPYQIAKNRYDTFVDILPVA
                     ITSIVNGDRVFLISNPCLLNSKITVRFISSHPTLNRTVDYGNIRDFIF"
     gene            complement(60318..60935)
                     /locus_tag="ACGI5H_000988"
     CDS             complement(60318..60935)
                     /locus_tag="ACGI5H_000988"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903837.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF488 family protein"
                     /protein_id="HFG9696712.1"
                     /translation="MEIFAIGHSNYPYDKLINMIKKYDINCVVDIRETPYSKYNIQYN
                     KEAFNESLRNSGFLYIYMGKEFGAKRTNKDVYTQEGYADFEKVAKEDIFLNGIERLKK
                     GCQMGYRIVLLGAMQEPIRCHRSILVGKVLNKEGFDVKYIMHEGNLAYQEDIEESLLD
                     KYFSDRKQLSIDNLLGSALTREEMIQEGYKLANKEIGYRTEKLGK"
BASE COUNT        19332 a        11121 c         6680 g        23971 t
ORIGIN      
        1 ctttcagttt tagtatttaa tccacatcag ataataatct taaaatgacc aaggtcttaa
       61 aactatttat ctttatcaga tttatcttct aaatttttat ttatatcaat aacattgttt
      121 ctttcttctt catctttttc taattttata gttaattgtt cttcaacttc tttagaagaa
      181 ttttcctctg taactgcatt ttcaatttca ttcagaggta actctttatt aaatgctttt
      241 acaaattgtt ctgcatctaa agtttcatat ataagtaaag cttgtgctac atactctaat
      301 ctatccatat tttcttgtaa tatacttctt gtcttatcat atgcaccatc aactatacgc
      361 tttgtttctt ggtctatctc aaaagcaact tcttcagaat aatttctctt acttgaaaaa
      421 ctattaccta ggaatacttc atcatcactg tcaaatgaca ttggaccaag tttagaactc
      481 attccatact ttgttaccat acttcttgca gtagctgtaa ctctttctaa gtcatttgaa
      541 gcacctgtag atacatcctt aagtactagc tcttctgcta ctctaccacc aagtaaaact
      601 ataatatttt ctttcatttc attttttgta gcatagaact tatcttcaac aggaagttgc
      661 attgtaaacc ctccagctct tcctcttgga actattgtaa cttgatgaac aggacttact
      721 tcttcaagta catgggcaca aactgcatgc cctccttcat ggtatgctgt aagtcttctt
      781 tctttctcac ttattacttt cgatttttta gccacacctg ctataacctt tgttatagct
      841 tcttctatag tttccatctt aattttcttt tctctttttc tagctgttaa tattgcagcc
      901 tcattcatta agttctctat atcagcagga gtaaatcctg gtgttcttct agccaagaca
      961 tccattttta catcatcact taatggttta tttcttgagt gaactttaaa tatagcctct
     1021 ctacctttta catctggtgt accaacaaca acttgtctgt caaatcttcc tggtctaagt
     1081 aaagctgggt caagtatatc tggtctattt gtagctgcca tgattattat accttgattt
     1141 accccaaatc catccatttc aactagaagt tgattaagag tttgctctct ttcatcatga
     1201 cctccaccaa gacctgcacc tctttttcta ccaactgcat caatttcatc tatgaatatg
     1261 atagctggag cacttttctt agcctgttca aataaatctc ttactcttga agcaccaacc
     1321 ccaacaaaca tctcaacgaa atcagaacca cttatactga aaaagggaac tcctgcttct
     1381 cctgcaactg ctcttgatag atatgtttta ccagttccag gaggtcctac cataagcatt
     1441 ccttttggta ttcttgcacc caattcaata tatttcttag gattctttaa gaaatctact
     1501 acctcctgca aatcttcttt ttcctcatct agtccagcta catctttaaa tgtaactcta
     1561 gttttttcat catctttatg aaccttagct tttgatttgc caaaactcat aacctttccg
     1621 cctccacctt gagactgatt cataaacacg aaccaaataa tcaccatgaa gaatattaac
     1681 agtaatgtag gcaacatttc gacaaaccaa ggtgtagatg gcttagcttc accaccaaaa
     1741 gttagtttcc cagccttagc ttggtctaac acctcatctg caagtttatt tcccatcact
     1801 tctgttggaa catatgactt aaactttgta tttgtatctt ttatagtacc ttctacagaa
     1861 gtttgattta caaagtataa tcttgatata ttctcatctg ttaattctct atatacttca
     1921 gagaatttta aatcttttat tttttctgta ggcttacctg agaattgaac tatacctact
     1981 ataattataa aaacaagtag ataaaaacct gcccctttta gcaacttatt caatatagaa
     2041 gccctccttt catacattgc tttgccctat aatttgttaa aattaatttt taatacttct
     2101 tttgtgcttt catcaatttt ataattttca ctgattttat aatctccaac acatattatt
     2161 ccttcaccat ctgtgattat aggaatttta catctttctt ctcttgggat ttttaaatct
     2221 atgaataaat ctttcacttt tttacttccc atagcaagct ttatcttatc accttgcctt
     2281 ctgcttctta ttactatacc cccttttacc ttattaaaat caaacccttt agatgaattg
     2341 tctaatttca tactcttata cctatctatg ctcattactt gggtctcaat aatttgtttt
     2401 aattctttta ttttaataaa cccattacta ggtacattgt aataaaattc aatttcctca
     2461 ttaacaattt cctcattcgt taatattata ctgtcttttt ttctataaac aaatatattt
     2521 cttggaagag ttaacatttt atttactttt gaattatctt ctaaagacat tatatcttct
     2581 atatgtcttt ggtcaacaaa attagtatct cctagtatat gttttatgga atttctaaga
     2641 actctaactt tgatagcatc atgtaagcaa acaaaatcgt ctaaatttat ctctacaaag
     2701 cctttttctt ttatatttga aacttctcta aatttagctt ctgcctcttt ctcaatataa
     2761 tcgttatcac tttttaaact attgctcatc ctcactatag attctattac atttgaatta
     2821 aaattatcct tcatatatgg taaaaggtct aaccttatct tatttctagt gtatatattt
     2881 tctaaatttg ttttatctat cctcggattt aaattataag cttcacaata ctcctctatc
     2941 tcatttcttt ccacgtctaa tatgggtcta attatgcaat tatctctaat ataatcaatt
     3001 ccctttaagc cttttaaacc tgttcctctc atgatacgca tcataaccgt ttcggcttgg
     3061 tcattgagat tatgacctat tgctatttta ttggctttaa tcttatcctt aatttcataa
     3121 aacatttcat atcttagctt ccttgctcct tcttctaatg ataatccctc attttcacaa
     3181 tattttggta cattaataga ctttacaaag aatataattc ccatatcctc acaaagttta
     3241 gatacatata atgcatcttt ttgagcttct atccctctta tttgatggtt taaatgtgct
     3301 gcatatattt ctatattaaa atcttttttt aatctattta gtacatgcaa taaacaaact
     3361 gaatcaggtc ctccagaaag acctaaaact attttatcgc ctttttgtat taaattatgt
     3421 ttatttatag tacttagtac cttatcaaat atcatattta tccctcttac acttagtttt
     3481 attcactttt aagtatactt tctataaaaa aacgctaaac ccttgtatca attttaagaa
     3541 attaaagttt aatataaata taataatacc aaataaatta aataaaaggt agttttttca
     3601 ctacctttat aaaatttctg gaaaatagcc atagttatta tttagtacct atgtatatat
     3661 ctattttatt cctacctaaa aataaatctt gtacctttat attatagtct attttcaatt
     3721 ttatgtgttc cccttcttgt atatttatat ctaattctct tgtatcaata tcaattaata
     3781 aagtaccttg tggggtcaca tactttgtag tactactttc tccacattta aacagcattg
     3841 ttgagttaat agcaccaaac tttttgatac taacttgatt tttaagtatc tttatagtat
     3901 tagttatttc tatatcttct tctttttcct tgtaaataac atatattcca tcatttttat
     3961 aaaaaatttt accaaaggca gtcatctcta tggtgtccat atttcctttt tcatcatatt
     4021 gtctagtatt tatacttatt tttacactca acgatttttc ctccatagat tcttcatata
     4081 aactagtatt tttgtatttc tactttttga atcttatcaa tttttttctt taagaactct
     4141 cttgctatat ctgaaaattt ttcaggtata tctgatacat aatattgata agttccatga
     4201 atttctgtat tgtttataat attttgcacc tctaaaatct tttttaaatc ctttgcagtc
     4261 tctttagctg gattaacaag ttttatatgc tctccaactt cttcacctat tgttctcttt
     4321 aaaataggat aatgagtaca tcctaacact aaagaatcta tatttttttc tttcaattct
     4381 tgtaaatata tctttgctgt cagtttagcc acttctgtat ttgcccatcc ttcttcaaca
     4441 ataggcacaa ataaaggaca tgctttatta acaatttcta tactctcatc tattttagat
     4501 atttccaagt tgtatgcttt tgaacttata gttccttcag ttcctattat tcctacaatt
     4561 ttgttttttg tagaacttac agctgttcta gctcctgctt ctataactcc aattatcggt
     4621 atatcatatt tttcttgagc ttcttttaag cttcttgcag tagcagtgtt acatgctata
     4681 actatagctt ttacaccttt tgtttttaaa aagtttatag cttgaaaagt atatttaatt
     4741 atagtttctt tggatcttga accatatggt attctggcag tatctccaaa gtatattata
     4801 tcctcatttg gtaatatctt cattatctct tttagaactg ttaatccacc taatcccgaa
     4861 tcaaaaactc ctattggttt attgttcatc tttatacaac acctacttta catttttgtg
     4921 tttaacaaca acttatttat cgctaaaatt tatatttata ttcataatta atatattatt
     4981 acctaaatga ttattatagt ttattttaca caaaaaataa aggagctatc ttaaattaga
     5041 aaataatttc tacaaaaaga caactccttt cactacttaa aaatttaaat ttattttgca
     5101 aacacatgat ttcctattct catataagga ttcaatctat ttatccattt gcaagtggct
     5161 atttctggat tccaaaaata tactgcttta ttagttgggt cagttccata aagagcttcc
     5221 tgagctgctt tacgtgctga gtctgttggt gccatcttta ttgaaccatc aagcacaact
     5281 gagaaagcat ttttttgata tatgacttct tctattgtgt ctggaaatct agggtccaat
     5341 actctattta ttactacagc tgctacagca acctgtccct catagctttc tcctctagct
     5401 tctcctgcaa ccaacttaga taataacatc aagtcattat cagataaatt tattacttct
     5461 ttctttgcta tatttttttc ttgtttgttt actttcttaa tattttctgt tggttcatat
     5521 gcaaatacct ctttaatagg cataaatata aaagtcaaag ctaatagtgt agccatcagt
     5581 ttactccacc tgtccatgat taaaaccact ccttacattc ttatttttaa aattttttct
     5641 ctaaatcctt gactacttca agtactttaa acttaatttt tactctactt gttttttttg
     5701 gtgtatcttg ttttattaac ttatattctt tatcagttaa aacttccttc aacttatcat
     5761 ctgtagattt atctatcact ccattagatt catcaacaaa acatagtgga gggaacataa
     5821 cacaccacca gttttttcct tcacctttcc caataataat ctttaatgct ttatattcac
     5881 cagctggaag aactatatta gaatattgtt tagtagggaa attgctatat tgtataccta
     5941 cctttacact gtaattatat ccatttttaa gaataatatt tttacttatt tcttccagac
     6001 tactatattc cttttttata atagcttcac tttcttttat actttttgaa ttttgaagct
     6061 ttggctgtaa atattttatt acttcatctc taacttttag tttaagttct tggtcttcat
     6121 ctgtattgct gtttgctata acatgaaatc ttattaattt atctttataa tcttttgata
     6181 tattgtctac tttttttacc tcaccattta ttactattgt cattattgat atgactgata
     6241 taagacttaa tattaatagt cccaatctaa tcttaatttt tctcattgaa aattccccct
     6301 caagataaat ttatatcatc aattatgtcc aattaaattt aatttattca taatattttt
     6361 taatactaat aaaaaaagct atcttaaaat gattacaatc attttaaaat agctttttaa
     6421 accttatatt ttataagtct ttactaatca tagccttatc tatcataaac tgctctgctt
     6481 tttctatatg ctctgtagca tacttcttgg atagctcact atcaccttta attatagcat
     6541 caagtaaata tttatgctct tcaacaatat tatgtgatgt atcataagca gacatatagg
     6601 taactctaaa tctatatact tgttcccaca atgagtttat taattggatt aattttttat
     6661 tattagttgc tttaaatata cattcatgaa attctacatc aagttttaat aacgcatcta
     6721 catcggattc caaagtgctt tttttaaatt cttctgatat atctttaagc tttttaatat
     6781 cttcatcact aattctttca gcggcaagat atgctgctaa gccttctagg cttgctctta
     6841 cttctaatac atccataata tcctttaatg acatatttgc cacatacgca ccttttctag
     6901 gcaacataac gactaaacct tctaattcaa gctttcttat tgcctctctc actggagtcc
     6961 tacttactcc taattgttct gctagttgca cttccattag cctttgacca ggctttaatt
     7021 ttccttctaa gattgcttct cttaaattct caaagactac atctcttaat ggcttgtaat
     7081 tatccaagtt cagtttagtt aaattctcca caaatttcaa cccctttttg actgctatta
     7141 acaacataca cctgtttata tttttttaat aattcttttt ttccaattag agcatcttct
     7201 ttatttttaa atagtccaaa aactgtagga ccacttccac tcatcataga acctaaagca
     7261 ttatttttca tcattacttg ttttatatca cttatttctt tgtgtttacc tatagtaaca
     7321 ttttcaagaa tatttaccat gctttctgat acagctttta tatcttcaga ttttaaacac
     7381 tctatcaaat atttattatt tggtcttttt ttaatattat tcaaatctaa tccttgataa
     7441 acttctttag tagaaacgaa taagtctggt ttgcatatca atatatttgt atcacatggt
     7501 aaacctttga tatttgttag cttttctcca ataccttgag ctaaggcagg tcttcctgat
     7561 atacaaaaag gaacatctgc gcccaaatta agtcctattt cttttaattc atcttcagat
     7621 aatctaagtt cccataggtg atttaaacct actaatactg cggctgcatt agaacttcct
     7681 ccagccatcc ctgctgctac aggaatattt ttttctatga atatttctac accttttttt
     7741 atataaaatt tatttttaag tattttggca gctttataaa caatattatc ttcatctaaa
     7801 ggaatatcta aactagtgct ttttaccttt atttcatctt cgtctaattc ttttatcttt
     7861 actatatcgt ataaatctat cgtttgcatt atcatttcaa caaaatgata accgtcttgc
     7921 ctttttccca agacatcaat ggataaattt atttttgctc tactctttag tcttataaaa
     7981 tccattctat cctccttgtt taaagaataa tgcatcacta acaataatat tatactacaa
     8041 aaaataaaat aatagggtat tataataccc tattatactt aattacttta aattttttaa
     8101 tattaatcta ctaatacgac ttttttttct aaaataagac acttcccagg cttaattggt
     8161 tcatcaagtt ttatatcatt aagttctgca atttcatttt ctgttgtatt gtattttttt
     8221 gctatattcc agaaagtatc tccttctttg catatatata cgattatgct aggagcttta
     8281 gataaatcat atacaccttg gtcttctccc ttgataataa aattttctgc tttcttatct
     8341 aatgcttcag taaatctctt aattttgata atcaagtcta tctggtccct attcaaatca
     8401 acttcgactt tatcaataca tgctgtatta aacacagatg ctgtatcagt tagattatcc
     8461 atttctatat catgttcaaa tggaatttcc tcactaattt tataaaccaa ttttaaacct
     8521 tcaactggga caaataaaat ttcaactttt atgattcctt gtataatgct tttatttcct
     8581 tcaatataac tattttctat agacatggtt ggacaaacgc ttacaatatc ttttatttgt
     8641 atatcatcat tatcatttct tatgccttct ctaaccataa atgtttcttc actacgtctt
     8701 aaagtcttat ttaattgaat aggtttgtgg tcaaatttta ttatcttttg aggcgaatat
     8761 gcatcttgta atacttctct tgtaacttca tctgtaactt ttaccttaca acaagccata
     8821 caatctattt ctaaaagacc tgtgttgctt tcactatttt gcttgaaaat atgattaaaa
     8881 tctgacatag acaacaatac ttcttcagtc ataccatcac taactccagg gacttctaca
     8941 aattgagtaa actcaatacc tactctatcc aactctacaa gttcaccctc atatgtacaa
     9001 gctaacggat ttatttctaa tactccacca ataataactt tattgtcagt cactctactt
     9061 tcttttactt taacacatgg atttaaactt attatagatt gaatttcctc tgtgtttatt
     9121 gttatagtat ctcttataga actttctgct ttttctattc caactatatc ttgaaaacaa
     9181 atttcctttc tgtgcttttg tatgcattcc acttgcgcca catcttttac aatgtctaac
     9241 ctttgctttt caaacaaact tccccttata ttcataagag ctcctacttt aatctttctc
     9301 tcattcatta tagtacaatc catatgctct acttctgaaa ataacatgta ttccatatct
     9361 tgaataacat tgtctttttc tattacttcg tttatatcta cttttccgtc tacattagaa
     9421 atagtatttt tatcatctgc aatatagatt acattataat taaaactacc tctgcaaagt
     9481 atcttcccat ctgccatttc aattttttta agtgatatgt atccttctgt ttttacaatt
     9541 tcatatacat ctaatttttt gtctggcaca actgcctccg cttcaatgaa tgtttgaaat
     9601 tttccaaagt ctattctatt gtcaacttta attacatctt taattaattc catagtctac
     9661 ctccttaagt attataaaaa tatcacacta tatttatatt taaggagcaa aaaaaaaatt
     9721 acacctattt ttaaataggt ataattttaa cttatttgta atttatcttg atctctaaaa
     9781 acttgcaact ttacattaga tgttaataaa tctgagtaac tataagatac tctaggatat
     9841 ccattacttt catcatctaa ctttataaca aacacgcttg gataaacttt ttctagtata
     9901 ccctcttttg taataatctg ctttcttcct ttattagctt tcaacaatat tttctttcct
     9961 atatgtctct ctaagcttac tcttatctta tctagagttt gaacagtagc cacaatatca
    10021 ccttctttaa cgtttatatg tttacataat atcacatata aacatttttg tcaaatgttt
    10081 aaactaatta ttttatatat tttttgcaaa aatgtcaata ctatttttga agatatacag
    10141 tataattatg ttaatttttg ctaatgtaat attgtttttg gcattgccca tctaaatttt
    10201 cctcttgttt cagaaccacc aattccctta acacctgtaa tagtctgctc tataacctca
    10261 tcaataggaa ctactacatc aattcttgaa caagcaattt tctccactat aaaaacaggg
    10321 tctaatgcat gtatcattat tcttccaggc gaacttgcat agtttgctcc tgcacttatt
    10381 attttttcat aatttgattg gcatgctcct gcgaatatga caagattatc caaatttggt
    10441 tgccatttac gtgcttcttt tactgtttta acaaaatttg aagagtttct atagttactc
    10501 atatcttcta tatctcctct ttttattgtc attgcatcat gacctgttat tactagtata
    10561 tccggattat atttttctag tagtgctctt acttctttat actgattttg ctctgaaaca
    10621 gctacaccta ctgcaggtat tccaagttga gcatatacat ccaagcaaat ttttaaatat
    10681 tctttatctc catctatctg tagtactttt ccaggcattc catatgtgtt aggatttaat
    10741 tgaagttttg gaactgctct agtcattctt ttttgtcttt ctttagcttt tcttactgac
    10801 ttatataata aattttctac atttttatct attaatatat cttttatatc aggtgctttt
    10861 actaattcta ggtcatcaat ataagcatct gctattactc taaatgcaat tccctttagt
    10921 atagctattt tctcattatt ttcatctaca ccaaaagaga ctattttaaa tactatatct
    10981 ttgttatgtg actttctagc tacaatgtct cctaccttca tagttaaacc tccaataaat
    11041 ttttatctta gtttatacta tgttcgatat aaaactttgt ttcctaatgt caaaaaaaca
    11101 tttcttataa tacttctttt atcactctta aagcattttt atagtatatc ttttctatat
    11161 catcttcact aaacccttct ttttttagag gttcatacag tttacccatc tgagatatat
    11221 cttcaatctc aacttttgaa tctattccat caaaatctga ccctagagat acaacatcta
    11281 ttcctccaac atttacaata tgttttatgt gtctaaccat atcttcaagt ttactttcac
    11341 ttttatcact taaaaataag tggaagaagt ttatacctgt aactccacct ttatttgcta
    11401 atactttaat catatcatca gttaaatttc tagaatgatt catcattgct cttgaattag
    11461 aatgtgtagc aattattggt ttagaagaaa tctttgcaat ttcataaaat ccaccatctg
    11521 aaatatgaga aacatcaacc aacattccca attcattcat cttatgtacc acttctcttc
    11581 caaaatcagt aagccctttt tctctatatt ctactttatt atgaggaaag ctcaattcat
    11641 tcacatgatt ccaacttatt gtcatcattc taacccctaa gtcgtaaaat ttctttaaat
    11701 tttctaattt accttcaagt actgcacctt cctcaataga taaaagagct gtaagtttac
    11761 cttctgattg gtttttcata atttcttcat agttagtagc taaagctatt tcatcactat
    11821 tttttttcat ttcctcatga aatttatttg ccatactcat gcaataatca aaaggatgtt
    11881 ttacttcttc agtatcaaca aaaagagcaa atgtttgagc taatgaatcc ccctttttca
    11941 atctgtctat atcaacagaa tatttattag acttaagttc acttgtttct acattttcca
    12001 ttaattttgc tatagtatca caatgtaaat caagaaattt catatttata ccccctgtat
    12061 attttatatt tatatctaaa aatagaaata gttgtcctta tagacaacta ttgacaacta
    12121 ttttttaata ttctttttaa tattacttaa tcttattctt cttttaagtt aggtattact
    12181 tttttaactt cttcaatttg atgccatgtt ttatctatat tattttcact aatatatttt
    12241 tttaaatcag ttaaagatgt aaaatcttta actgataaat tgtcatcatc atctgcaaat
    12301 cttaaaataa acatgagact cccttacttt ccacaacatt tcttatattt ttttccgctt
    12361 ccacatgggc atgaatcatt tcttcctatt tttgcttctt taactattgt tttagacttc
    12421 ttataagcct ttattatttc ttttctttgg tctgctggta gtatatcttc ccaaccttgt
    12481 aaattatata gccaatgagc ctcaacagtt accatattgt tatataattt ttcccaatct
    12541 atttttatag aaacttcttt atcagcttct acttcttcta aaactatatc ttcttttaag
    12601 ctttcactta ttccatctat gaatcccatg aaaaattcat tagtagttcc aaatttttca
    12661 gccaattcac ttactttacc ttcaacaaca tccattttat tatttaatat ttcattgtat
    12721 attccagctt caactttcaa atattcttcc cagaatttta cttctgcttc ttgactttca
    12781 tgattatcac ttaaatttct ccattcagta tataaactca tactttttcc tcctaagtat
    12841 acctatattt ttatagtttt tatagtataa aatcttttag ttagattgga agtttcttct
    12901 ttttgattat accatattct atttaaagtt aactcttata ttatatcata attaaacaat
    12961 tcttttaata cttttatagc atactcttgg tttataaaat aagggcttgt cgcaattgtt
    13021 attactttgg cttttttaat taagtttttt atcttgtaaa atttgagttc aaatggtata
    13081 tagtccatat cacttgaaaa tatatccaaa tctatatcaa gaacaaactc tgattctact
    13141 tctaaatcaa atccatatag actatctatt attattaatt ctgaaaatat gttatatttt
    13201 aaagcaggtt ttataaaact tcccacattt aaaacttcat ttgtatatct aaatacatct
    13261 tttagattat ttacatctac atcatagttc tcaggttctc tagtatcctt atgttggtct
    13321 acatgcacta acttgcatcc ttttgtaaac tcacccttta acaaagattt tgcccaaaaa
    13381 taaaatgcat ggttatgatt gtcaaacaca tatatctttt tatttcccag gacatattcg
    13441 accatattct ccaatccttt tgcttttatt tccttatttt catctacttc attaaatact
    13501 acctcattgc ctaaccttac atcatttaat gtaccattta ttagttttgg aacgtatatg
    13561 ctcttatttt ctcttttatc atatgaaaat acattatttc ctactggttt ttctatataa
    13621 aatccactat attcataatt ttccataaaa ctttatttcc tccattgtta tataaatata
    13681 taagttataa ttttaaaaat taaaatgcac ttattgtaaa tcatatcatc tattatagaa
    13741 aacatcttat ataactaaat ataatatctt ctctcaatat gtattataca ataagtgcaa
    13801 aatatattta tataaaatat actacattcc tataacaaaa ccatcagctt caattggaag
    13861 gtaactaact cttctattca actccacctt tccaaaaaat actacccaat atggtctaaa
    13921 aatactttca attttaacta tttcaatctc tgggattcct cccataaacc tatgagttaa
    13981 tctcatagcc attttatttg cctttgcttt tactcttcgt tcgtccttat cactatactg
    14041 cacaatatta caatccacat tttttacaac ttcatatgta ggaaaatctt gtactatact
    14101 accagaacct gtagaaccat tcactaaaat ttttaattca tttatatcat tagaatatct
    14161 cctattcttg aaaatggatt tcgttttgtg aattttaagt gtgataattt taaactctat
    14221 ataatgaagt ctaacttcat gagcatattt gttctttaat attagcttac taaataaaga
    14281 attttttcca cttttagcta tctctatagc ttcttctttt gtaattctta taggtaacgc
    14341 tcttatatcc ataaaatcat tctctttctt atttttttct tgtcattttt aaaactctat
    14401 atatataatc aaaaaatatt acaattacaa ctgccataac tccatatgga attatttttc
    14461 caactataat atcatttcta gtcaatatac cataaaatat aaatcctgtt attaaaaagt
    14521 acaataatac tagaaaaccg tctattccaa gccattttat ttctaaatct ttttttacct
    14581 tagacactaa tttagacata gcagtttctc cttttataga ttattttgtg tatttaaatt
    14641 ttcaccgatt ctattaccaa tcatccatgc aataaatgaa aaaggtatag ctatcacaag
    14701 aggctctaac tcaaagctct gaactggaaa tattttaaaa taaccaaaag tcactccacc
    14761 aacaatcatt cctaaaatac cacccataga tgttcttctt ccatttccaa gaagcccacc
    14821 tactataggt acaaatgccg aacccatcca aatacttcct acaaatatac atgcatcata
    14881 tacattttca aatctaaatg ctacgctaag ccccataact gctgctaaac atacacctat
    14941 tctagtaaac tttactaatt gtttctgaga taactctttt tttgtaattc ttccatatat
    15001 atcatttgct aatgtagccc cagctgctag ataatagcta tccaatgttg atattataga
    15061 acctaaaatt cctattataa atattactct tattccttgt ggtaatgtat ctaaaactaa
    15121 agttatatat ccagcagctg gagccatttc tggataagta gctcttacta taagtcctgt
    15181 catagttaac accatgtcaa aacatatcca tagtgaaaaa caggttaata aggctcttct
    15241 tccaacctta ggagaatctg ctgctgaaaa tctttgataa aaagttgggt ctgaataagc
    15301 tccaaaagaa tatacaatta acatcaatgc tttcatagct gacatacctt ttgtagggtg
    15361 cataagctgt ggtgcatctt tgagtgcttc tgtaagacct tgaaaccctc ctatttgttc
    15421 aaattgacct ggcataacca tagttaaacc aaataccata caaaaaaaca ataccatatc
    15481 tgtaatggca actcccataa gcccaccaag tactgtaagt acaacgacta ctcctaccat
    15541 tattaatcct attaattctt tatctatttt ccatgctacg ttacctatag ttcccatagc
    15601 agttatttct ccaagttgtg cacaatatat aaacatcaaa attgccccaa ttatagcaac
    15661 atgcttgcca taaaaacttt ccagtaaatc aggaactgtt atattggttc ttatatgaat
    15721 ccttggacca acccacaatg ctaaaggcat tctcccaata tgtgcagcta ttgaccaaac
    15781 tgcccatgca gatattccat atatagccgc atactctaca ctacctactg taccaactcc
    15841 tccataccat gatgcaacca aagttcctac tattaaggac catggtaaac ttcgatttcc
    15901 taggtaataa ctttccatat cttttacatt tctagaaaaa taataaccta ttcctaataa
    15961 tataaatgca aatataacta taatcccatt ttcccaaaat gttaacatat ctaatctcca
    16021 cattcttata ttttaatttt taactttaat atctaaatat gaacaactct acccatttcc
    16081 ataaaaatag gtagagttat ataataatta taagtattta agtaatcttg ttattaagca
    16141 attttattgt ttaaaccttt attttctctt ttatttattt tatttaaagc ataagtagca
    16201 aatatcccta taactgcaca tactacagat aaaataaata tatatgtata tcctgtttgt
    16261 ccatatttat ctaaccaatt acctgcaata gtgtaataaa acgcatctgg agaaaatcct
    16321 ataaatgaag caaatccaac tactgctcct gtagtttcta aagatatatt agactctgaa
    16381 acagatgcaa agtatatacc tctaaatcca aataaaatta cacttagtat tatcatgttt
    16441 attacagcta tccatataaa tcctgtactc ttaggaataa ccaagtaagc agctgtactt
    16501 actgtcatta atataaatcc tacaaacatt actcttatag atgaaccaac tttatctgtt
    16561 ataacaccag caactggaga tgctcccatt tttataacat aagttcttat tattgataaa
    16621 gcagaaacta gagtcattgg cattacataa acttctgata agtatggact taaataagtt
    16681 aaacttgaga atactaaata agttgaaaat attataagac caattaacca agcctttggt
    16741 attgtaacta cttttaacaa tgacttaata cttaatcctt catctgatgc tccactatct
    16801 tttttctctt ccactaagaa aaatagaagt ataccacata ttatagatgc tgcagaatat
    16861 aaccatacta catatttgaa tcctactgtt atttcagcaa atttaccaaa gaaataaaga
    16921 cctataaaag aaattaatgt acctgataca cctgataacc cttcataaaa accaaatatt
    16981 cttccttgct ctgactcact tccttgcatt ctaacaacct taacagaggc tgagaagaag
    17041 gttaatattg tcgtaaatcc ccataataca aatattaaaa gtatcatact atatgatggg
    17101 aatgtagaga aataaaatcc aagtatccct gaagcaatta aagaaaaagt tattaatttt
    17161 ctaactgaga atctatctgc aaaccatcct cctataaaat aagataccat tcctactaat
    17221 ccatataaac tcaataagtt ccctatttgt gtatgactta atgctaaagc ttgttgcatt
    17281 gggtcataaa atgatgattt catatatggt aaactataca tagctgttgt tccaaatgcc
    17341 aatatgaata ttatcaaaaa tcttttaaca ttatttttgc tttccattga ttctctctcc
    17401 ttaaaatttt attgtttata atctcattca tataatttta ttttaatttt tctattgctt
    17461 gtttaaaatc atttattata tcatttgaag attctaatcc tacagctatt cttattagat
    17521 tttccccatt catttgaact aatgtatgct cttcccctaa gcttgttgct attgttgcaa
    17581 gctctaaaga gttcattaat cttctactag cttggtctct tgtcaatcca ctgataccat
    17641 ccttaagttt aaatgaaact acgcctccac ctaaaccatt catttgagtt ttacaaagct
    17701 catattgagg atgtgatttt aatgctggat actttaccaa ttccacattc tcttcttcct
    17761 ctaaaaactc tgctactgct aatccatttt cacaatgctt tttcatcctc atatctaacg
    17821 ttttcatacc ccttaaaatc atccatgcac tcattggtgg taaagatgct cctgtaaaac
    17881 aacataaact tggccatcta actaaatcta ttaattcttt tgaacctgct actgctcccc
    17941 ctaaagtatc tccatgtcca tttataaact tagtaagact atgtattact aaatctgcac
    18001 ctaaatctat tggtctttgt acaattggtg tcccaaaagt actatcaact atagctaagc
    18061 ttttattttc atgagcaatt tctgctattg tttttatatc tactaagtct aatgatggat
    18121 ttaaaggact ttctatataa actattttag tatttggtct cattgcttct tttacatttt
    18181 gtggatttac tgcatctaca aatgtaactt caactccaaa tttagataac aactcagaca
    18241 tgaataattt agtgtgtgaa aatattccat ctgaactaac tatatggtca ccacttttta
    18301 ccaatgctaa tatagtagat gttattgccc ccatgcctga tgtactagat atggcacttt
    18361 ctgcattttc aagcatagcc aacttagctt ctaactctgt aagagtagga ttacactctc
    18421 ttgtatacac atatccccat gtcatacaca actcttcaaa atgctctact gtctttgcag
    18481 caaatgttgc tgtttgacat attggtgtag ccaatgcacc tgttgttggg tctgcactat
    18541 gtccccaatg tattattttt gtctctaaat cttgattaat attgttactc attttgattt
    18601 cctcccattt tgacttattt atacaacgtt ttccctgcca aatttcatca atttagctta
    18661 gtcttaatac attttttcaa gtatactttt ttatttgtta taatttctaa aaatatgaca
    18721 cttattttgt ttttttacag ttctaattat aaactctata gtaactatag agtcaatatg
    18781 tttttgatat tttttttaca atgtttaaaa tagtcaatac aaaaataggt atatcttaga
    18841 ataactaaag tcatcctaag atatacctat ttttatatca caatataaat aattacatat
    18901 aagcattagt ttttttatca taaatagatt tttcaagatt tatcattttt tcataaatat
    18961 attatagtta aatattttaa tattacctaa catctacaat aaaatatact cttaaaataa
    19021 aattatataa ttaaaaatac tctataaaag ctaaaaagtt tttctattcg ctacatctaa
    19081 aaataattag atagaggtat aaatgtattt agtttattta tacctctagt cttttataaa
    19141 ttatatctct actaaattga ttttttagca cgaataagtg tgctcttgga gataccagtc
    19201 atcttcacaa cctctctata tggcttagaa tttaataacc ccaatgcata ttgtatctgt
    19261 tgattgctgt atttctttgg cctaccatct ttaaagtcct ttttcttttt agcaaattct
    19321 tttcctaatt gagtacgttc tattatcata tttctctcaa gttctgcaac tgcaagtaat
    19381 gtagtcaaaa agaatttacc cattgaagta ttttctaaaa ggcctatatt taaaatatga
    19441 acacttactt ctttagcaaa taaaccttct attagttgta ttccttctga tgtacttcta
    19501 gctagtctat ccagcttagt tgcaacaagt aagtctccct tttttagaga tgatataatt
    19561 ttttcaaatt taggcctgtt tgtagtagtg cctgtataag tttcctttat tattttagca
    19621 tcattatatt tattcaaaat ttcttgctgt tgctgataca aactgttgtt gtctgtttga
    19681 ttttttgtac ttacacggca atatccatat ataataatca tcacttccta acataaagat
    19741 tttgtacaga agttacccag aagcttgttt ttacttatct ttatccattt tactaaaacg
    19801 atttttgggt gtcaatactg ttaacttttg acaccataat aattccttta taatttgttt
    19861 gactatgtca aaaattacca atataatgaa attaatgagt ttatacaaat tggaggaaat
    19921 aatatgaata gtctgttaaa agaagcaata gatgaattaa aaaacatcca ttgcggggaa
    19981 gtttttttat taaaagaatt gttcaaaggc tatgaatgga acaggttgga gatgaatatc
    20041 agattgaaat taggaaaact ttttttgtat gaagtggtaa ctaatcccaa tttaaatgta
    20101 gaggtcatca ataaaaattc tgcttatcag caaatgtata aaaaaaaata gtgacttaaa
    20161 tgtatataat agtataatct tcttattgat tcaaaagtta aaacttttaa tacaaaacaa
    20221 tcattctatt ttaacattta tcaatatgtc taaatttata taattaacac atacgaatag
    20281 tattgtttaa atcacattat ttaagataga taaatcttaa ccctactcca gcataaatac
    20341 taaaataggg cttagaatta tctatatttt tatcccataa aatgcttagc tcttcctctt
    20401 gattgaacat atatatctgg ggaaatacaa tagaagcgta aatttataaa atttccaaag
    20461 tcagaaaact tcagttcaaa cttaggtata ccaaaacttt caggtgctat ttcgtcaacg
    20521 ccaaaataga tgataattcc attatctgta agataaaatg cttggtcttc aggtataact
    20581 aactcaacat tagaataata catttctcta ttttcattta tttgagattt aatgtaatca
    20641 gtaattatat taatataatc aactccatct ctaaaaatgt cattaagtaa aagttctttt
    20701 ccagttgtca aatctatatt gtaattattc aatgtattgt atttaggccc atagttatta
    20761 gcaaacccca taaggtttaa tatcatactc agtacataat ttttattaaa agtaactgcg
    20821 taactggtag atacccaata gctttgtttt ggaagtgaat tttgagaagc tgcgttatta
    20881 tattctcgtt cttcttcctg taagccattt ttaaaattat ttacagtcat tcttacagca
    20941 ttgtttatgt tatttaaaat aactgggttt acatacgtgg attgatttct aatattgtat
    21001 ataacaggat actttacatc atatgaaaaa tacttacttc tttcaaaatc ttcattaaat
    21061 tgtacatata atatattata tgtacaggta tttgtagatt gataattttc cattaaaatc
    21121 ctcccccttt tataaaaaaa tcagatacaa tataatatgc ttaaaacagt aataatgtta
    21181 atggtaaatg taaagaatag aaagtatcta aaacagcaaa aaatgactaa ttttgtggta
    21241 taatacatag gattgagagt tattttatag gaggaaaaat atgttattat tagcagataa
    21301 atggaaagat tatgaactta tagatatggg aaatggagaa aaattagaac gttggggaag
    21361 ttatgtactt agaagaccag acccacaggt tgtatggcca atggaatctg aatgggcttt
    21421 atggaaaaac cctcatggac attatcacag aagcaataaa ggtggaggtc aatgggaaca
    21481 caaaaaaaga tatccagaac aatggactat aaattataaa aacttaaagt ttcacattaa
    21541 accaactggc tttaaacata ctggattatt cccagagcaa gcagctaact gggattggat
    21601 gatagagaaa ataaagaaag ctaacagacc tataaaagtg ttgaatcttt ttgcatatac
    21661 aggtggagct actgtagcat gtgcatctgc tggtgcagaa gtatgtcatg ttgatgctgc
    21721 aaaaggtatg gttaattggg caaaagaaaa tatagaatta tcaggtctta aaaatcaaac
    21781 agtaagattt atagtggatg atgttgtaaa gtttgttgaa agagaaataa gaagaggtaa
    21841 aaaatatgat gcaataataa tggaccctcc ttcttatgga agaggtccta aaggagaagt
    21901 atggcaaata gaagaaaagt tatacagttt tgtagattta tgtatgggag ttttatcaga
    21961 taacccttta tttttcttaa ttaattctta tacaacagga ttttctccaa tagttcttga
    22021 aaatgtattg tctacaacaa taggtaaaaa gacaaataca ggagatatat acggtgggga
    22081 attaggaata ccagcttcca gagatggtaa gatacttcct tgtggtatat ttggaagatg
    22141 ggagaaaaaa taatgataaa agtcatatat gaagataacc atttattagt tgtagaaaaa
    22201 ccagttaaca tattgtctca aggagataat actaatgata aagatatggt aaatctttta
    22261 aaagactata ttaaaaaaaa gtataacaaa cctggaaatg tatatattgg tttaatacat
    22321 agattggata gaccagtagg tggagttatg gtgtttgcaa aaacatcaaa agcagcatct
    22381 agattgtctg agcaggtaag aagtaagact ttcaaaaaaa cttatctagc tgttgttcat
    22441 ggcaagataa aatctaactc agatatacta aaagattttt tatataaaaa taaaaaaact
    22501 aatatggtaa ctgtagtgaa aaaaagccat aaagatgcca aagaagctga acttaactat
    22561 aatgtattag attttaaaga aaatctaagt ttagttcaag ttaatttaaa gactggtcgt
    22621 tctcatcaaa taagagttca atttgcaagc agaaaacatc cattatacgg agaccaaaga
    22681 tatggcaaag aaataaataa gattggacaa caaatatctc tttggtccaa taagatagaa
    22741 atttgccatc ctactacaaa agaaaaaatg gaatttacat gtcatccacc tgacaaatat
    22801 ccatggaata tattttaaat ctcaaatgag gtgattatat gagtaaaaaa ttttcaatag
    22861 gagaaatgtc taaacttcat aaaataagca tacagacact aaggtactat gaccaaatag
    22921 atttatttaa acctgttcat gttgaccaag aaagcaatta cagatattac tcaattgacc
    22981 aattttcaca attagatatt ataaaatatt taaaatattt aggtatgcct ttaaaagaaa
    23041 ttaagtcaaa gcttgatgaa aataatgaag aaattctaaa attactaaca aataaaatta
    23101 atatagtgga tgaaaaaatt aaagaattag agcttataaa gaaggtacta agcacaaaga
    23161 aagaaactat ggaaaaaggt atgaaagtag atgaagttgg taaaatagtg agaaaacata
    23221 ttccacgaag aagtatctta tctatagagt atgaagaagg attaagtagt gaagaaacta
    23281 tggaactttc cagaagacaa atagcaaata tattagaaga taatatatct gtgttctatg
    23341 gtggagtaag tggacttgta tctatagata aatttttaaa agaagataaa gttatttatg
    23401 acaatagttt tgttactgtt gaaagagact tatttgatat aaaatcacaa aaacatataa
    23461 cagaaatttc atctggtgat tttatttgta tgacatataa agggccttac aaagaaaatt
    23521 ataccgcttt taagaaactg gttgattatg ttgaatataa aagaatacct attgaaaatt
    23581 atatatatga aatacctata atagaccctc tgtctacaaa caacgaagag gaacttctaa
    23641 cagaaattca aatacaagtt aaaaagagag aaattgactt aagatgtcta gtgtagtaat
    23701 ctagtttact tacacatctt aatatagttg tctattatca acatatgatt tttctagata
    23761 gtgattccta acagtgagat tttcaaaaaa taggaggaaa tatggctaat gctaattccc
    23821 tcctattttt aattaagcca tatcatttta attaagccat gtcatcacga agtgcatcaa
    23881 taatattttc tttttttatc ttattaatag tatacaacat tgtaataaat actataaata
    23941 aaacactaaa tatactaatt ccaatactaa accatggaat cacaaaatca atatcatctg
    24001 taaccattac tttatgaatt agccatgaag aaattactgc tataggaagt ccaaagaaca
    24061 atgctctcat gccataaaag gcacactcaa aattcatcat cttttggaaa tcatgctcag
    24121 acattcctac agagcgaagc atggcaagtt ctctacgacg taacttaata ttagttgaaa
    24181 ttgtattaaa cacattggca atcgaaatca gagaaatcat aattatgaaa gtataagcaa
    24241 aaacattggc aataaaaatg taattacggt tctcatccat cattccatac atattgtaca
    24301 gattgtactc attcgtaact ccctcactct caataatttg ctccatttct gcaactgact
    24361 gagtaggatt tttcgattga aagcttaaac tttcaattcc tgtagaaaca ccaggaatct
    24421 caaacttatc tttggctgaa taaggagcca atactctgaa gcttgctttc ttcacatctg
    24481 aacttctgat tcctggagga gaatcaggtg gcactacttt gacaaatgaa atattcacat
    24541 tttgtctctc aggtatctcc aacttgccat tagtttcagg agtgaggcta acattcatag
    24601 aagaactgtt gaaaatatca ataatattat tatcctttgt taccatagaa acagcaatca
    24661 gttttgcatt ttgtccagta tattcttctg ctggtaatcc aagactttta ataatattca
    24721 gataagttct atcatcaaga aattgcatat ctactggtaa ttcaagcatt tcactcatag
    24781 aatgtgaacc ctcatagttc aaataatcgt ctgtaagctc acttactttg gcaacacatg
    24841 aataggtcat aagtttctga tacaaacctt cgtaaacacc atttgcagtt tttagcttat
    24901 cgtaaagctt caacatttcg ttgtctttca taccttgtgt agaaaaaata atatcctggt
    24961 cagtaacctc tgacctctga tttgacatct gttttaggtc tgctactaaa gcacttgtag
    25021 atataaatag aactatgctt aaaacaagcg acaatacaat acttcgataa cgtttcttgt
    25081 ttcttttaaa gtttttcata gcaagaactc cctcaagacc ataaactcgc tgtgttagtt
    25141 ttgatgtctt cacagattta gattcaattt ttacctcatt tgtctgacga atacactcca
    25201 tcactggtgt gttggcagcc tttcttgctg gtatgtaagc agaaattaag attgtaacca
    25261 tacttaccac tgctgcaacg atgattgcag ggatagacaa tgttaatgtc aacggaacgt
    25321 ttacatagag aatatttgca aagtttttag atatgacaga aatcacaagt ccaatactga
    25381 ctataccgat tgcaacacca attggtatac caatcgcacc aatgcaaatt ccttcaaata
    25441 gcaccgaatt tcgtaactgt tttgctgtag ctccaacaga tgaaagtatt ccaaattgat
    25501 gtgttcgctc gttcaatgac atgttaaatg aattatatat tagaaaaatt gagcctagca
    25561 tgattatggc aagcacaatg ccaccaaccg agtacaaaaa catattgaac aaattgttat
    25621 cagagacacc tatgaatcgc aacacattgt cattgaaaat ggaagcatgg tctttagtgc
    25681 tacttgtgta agagcgaatc tgatgtggat ttttcaatgt gacaaaaagg ctaagactgt
    25741 cagtcttgac ttgtttatct tctttggtta tcaaggtata tcctggtgca gaagattctt
    25801 caaatacggg ctttctacag atacccacaa ctgtataagt tttcttatcc tgtggcacaa
    25861 aaacttcact cccagcagtg tatgggtcac tctgaccaag cttttcattt tcactcattc
    25921 gtttccctac atccaaagaa atagtatccc ctactgcaaa tttgacacca ccatctgtcg
    25981 caactttact tgaaacaaga atctctctac tattttcagg taatcttcca gaaattaaag
    26041 ttataggcaa agtatcaaaa gcttctttgc taaatccagc aataaaaaga tatggtttat
    26101 ctggatttct gttaccttca agtgttgcat agccaatatt ttcaaatgtt gcagtatttg
    26161 caacttcatc attgactctt tgttcctgta caaaagaaga atccacatcc aaaaactgga
    26221 catgccaatc accatatttt ataatagctc catttatcat atagttcatc aaagaaactc
    26281 caaaggtagt aactgctgta atcatagcag ctgacagaac aactcctata attgttacaa
    26341 gagttcgagt tcgattcttt ttcaatcctt gcagagcaac tttgttaaaa atgttcatta
    26401 acgattcacc ttcctctcat cacgcactac ttttccatct gaaatacaga taattctatc
    26461 tgcctgtaaa gcaatgtttt catcatgtgt gacaataatg agagtttggt gatatttact
    26521 atggctctct ttcagtaact ggataatctc ttgtccattt ttactgtcta agctacctgt
    26581 aggctcatca gcaagcataa ctgctggtgc attcatcaat gcacgaccaa tggcaacacg
    26641 ttgctgttgg ccaccagaaa gttgatttgg taaatgtgtt tttcgttctt ttaaaccaag
    26701 taattctaac aagtcattta accgttcttg attgacctta cgcttatcca taagtatagg
    26761 caatgtgata ttttccacta catttaatgt gggtatcaga ttgtgaaact gataaatcaa
    26821 tccaacttgt cgcctacgaa aaatagcaag tttttcattg ctttggccat atacatcttg
    26881 cccctccaga tatatctttc cacttgttgg tacgtctact cctgcaatgg aatgtagtag
    26941 tgtagattta ccagaaccag aagaaccaat gattgcagta aactcccctt tttcaatagt
    27001 aagtgagaca tggtcaagtg cagtaacctt attttcattc ttaccataaa ccttacataa
    27061 atcttcaatc tttaaaaacg ccattatata agtctccttt catattttat aaatatatca
    27121 tagaactttc aacttacatt taagtgacat ttaaatgaga gattcgtcac tttggaaaac
    27181 gaataacaaa tattgcacca ccttgtgggt gattttgtgc agtaattgtt cctccttgtc
    27241 tcataataat cgtcttacaa agtgccaatc ctattccata accggctgtg cttgaatttt
    27301 tcccacgata aaatctgtta aatagacatg gtaaatcttc ttttttaaag cctgctccgt
    27361 tgtcatgaat agtaagttga gtaaacaaaa agttgtcctc acaaatgata tcaatttttc
    27421 cattatcacc cacactctcc atgcagtttt taaatatatt ttgaattgct tctgaaagcc
    27481 aatttaaatc acccaaaatc cttactcctt ttggtatatc aatatgtaaa gtgatattgt
    27541 gcagttccat gggaatcaaa agttgatgaa gtgcagaact aatcaaatta ttcacatcaa
    27601 tttgttcttt ttgaaagact acaatacctg catctaaacg tgataatttt aaaagggaag
    27661 taatcagcca gtccattcgt ataagtaatt cctctgtttc tcgtatcaac tcttttctct
    27721 catcttcatc agaagtattc tctaacagtg acaaaataag agttactgat gtaagaggag
    27781 tgcgaagctg gtgggctatg tcagctagtg agtcagcaag gtgttctttt tcttttttca
    27841 gtgcgtaatt ttgctctcta atgcgtaacg tcattttagt tatttcactt tgtagaatag
    27901 aaagctcacc ctcatctgat tcagcaatat acagatggtt agcattatga agcacaagat
    27961 taatttgttc tgaaatctgt gcaatacttt tgtatcgatt tttagtaaac acaaaaaatg
    28021 ctattccaaa ggtagtggca gaaacaatag aaagtattcc agtcataata ctgattgcaa
    28081 atcccagggc tacagtgaga atagtaatta ataagaataa aatagcaaat tttcgaaact
    28141 ctctatttcg aaacataact tccccccaat ctataccctg tcccacgaac agtcaaaatt
    28201 atttgtggac ttgaagggtc atcttctatc ttctctcgca agcgtttgat gtacacagtc
    28261 aatgtgttgt cattaacaaa ctcacctgcc gcatcccaca attcatcaag taatcttacc
    28321 ctcgtaataa tacttttagg attgctaata aacaccaata acaaacggta ttctaaagct
    28381 gaaagaaaaa cctcattgcc attctttttc acaacaccag ttgctgtatc tacataaagc
    28441 ccacaaattt caaaagttga cccaaaacgc ccactttttc gtagtgctgt tctaattcgc
    28501 gcaatcagtt cacgtggacg aaaaggttta gtaatataat catctgcacc catattcagt
    28561 ccagtaacaa cacttgattc atcaccggaa gctgtcaaaa agataacagg aatgtcttgc
    28621 ttttctttga tttctgtgca aatcgtaaac ccatttccat caggtaaaga aatatcaata
    28681 agtgccaaat caaatttatt cttagcaatc tctacaagtg cttcacttct tgtggataca
    28741 tgggttacta taaatccttc tgaattaagc aaaagaataa gatttttggc aattgcttta
    28801 tcatcctcaa ctaaaaatat ccgtttcatt tactttcatc ctcctttatt ttattagttt
    28861 tatatattcc agcagagcaa tagtacacta ctattttact tatcattaca caattttcag
    28921 tagtttcttt tgttcttata taatccatgc ataatacctc cattgattta ttatatttct
    28981 tataacataa atacacaaga taagacaaaa aacataatgt aagtgcaagt tttttaactc
    29041 actaacttat aaacatacac tcctactaac actactttct tgatgacaca tcttacaagc
    29101 ttatattcat acatcaatga aaaattaaat ttatccattt attaaaataa aaggcaatag
    29161 cttctatagc taatgccctt tatcttaaaa tgatttaaat actatacaat ttttataaat
    29221 ggctataaat aaactcgtat agaatataaa atttatctac agtcttttgt tatacaaaat
    29281 ttataacctc ttatagaaca aatttaccac tttgcaaact tatcactttt actcagctat
    29341 attataaact tttaatttat ctttgtttaa atgtttcttc ttaacttcta ctaaagcttt
    29401 tagcgtatcc aaagatgtca ttatttcagt agaaaattca atggctgttc ttctcatctt
    29461 aaatccatct cttgtagagt catttccttt agttggtgta tttattacta tatcaacttg
    29521 tttatttctt atagcatcta atatgtttgg tctaggttct tcaattctat ttactatatc
    29581 agcctctatt ccattttctc ttaaactctt cgctgttcct tctgtagcaa caaaagtata
    29641 tcctaattct ttcatatctt ttgctatctc tataaactca tctttatcat gattatttac
    29701 agtagcaagt actactcctc tttcatcaga catatgtcta cctgctgcca agaacccttt
    29761 atataaggct tcttctaaat tttctcctac acctaggact tctcctgtag acttcatttc
    29821 aggtcctaga cttacttcaa ctttagataa tttagacatt gagaatactg gtacttttac
    29881 tgatactaat tttggctctt tgtaaactcc tgtaccatat cctaaatcct ttaatttagc
    29941 tcctaacata cacttagtag ccaagtcaac tattggtact ccacttactt tacttatata
    30001 tggaactgtt ctactagctc tagggttaac ctcaattata tataattcat tttgaaattc
    30061 tataaactgt atattaacca taccaagcac attaaggtct aaagctattt ttttagtgta
    30121 ttctactatc ttttctttta tttcatcaga tatattttga cttggataca ttgttgtact
    30181 atctccagag tgaactccag ctctttctaa atgctccatt ataccaggta tcaatatatc
    30241 ttctttatca catatagcat ctacttctat ttctctacca gttagatatt tatctataag
    30301 tactggattt ttatggtctc tatcaaatgc atcatccaaa tactgaatta gtttttcttc
    30361 gttataagtt atttccatac cttgaccacc aagtacataa gatggtctaa ctaatactgg
    30421 ataacctaac tccttagcaa tttcaacacc ttcattagtt gtccatacac cttttccttt
    30481 tggtctattt atatctagtc tctctagtaa atcatcaaat ttttctctat cttctgctgc
    30541 atctatatct ctaaagtctg ttcccagtat aggtatattt ttttcatgta aaaacttagc
    30601 caattttata gctgtttgtc caccaaactg tagtattaca ccttctggtt tttctttttc
    30661 tattatattt aaaacttctt cttctgttaa tggttcaaaa tacaacttat cagatgtatc
    30721 aaaatccgta cttacagttt cagggttatt gtttacaatt atagtttcta ttcccatttt
    30781 tcttaaagat tttacacagt gaactgaaca atagtcaaat tctattcctt gacctattct
    30841 tattggacca gaacccaata ctacaacttt tctcttatca ctaactacta cctcatcata
    30901 ttgttcataa gttgaatagt aataaggtga tagagcttca aattctcctc cacatgtatc
    30961 aaccatttta taaactggtt gtatattata taaacttctc aattcatata atttttctgg
    31021 gcttatcttc attaagtcag atataccttt atcagaaaat ccctttttct ttaattcatg
    31081 taaatattct ttatctaagt cttctatttt tagaactttt aacttttctt cttgttctac
    31141 tatccattta aatttattta taaaccactt atcaacacca gttatttctg atatcatttc
    31201 tactttatag cctcttctta tcatttcagc taagtcaaat agtctctcat catcaggtac
    31261 tactactcta gcctttaatt cttctaatgt tctaccttct gatggagcat gaaccaatga
    31321 atattttcct gtttcaagtg atcttatacc tttaagaata gcagcctcaa agttacttcc
    31381 tatactcatg atttcaccag ttgccatcat cttagttcct aattttctat tggcatgtct
    31441 aaatttatca aatggccact ttggtatttt tactaccaca taatctaatg ttggctcaaa
    31501 acaagcataa gtttttttag ttactgcatt ttctatctca tccaaagtat aacctaaagc
    31561 tatcttagct gctacttttg ctattgggta tcctgtagct tttgatgcta gggctgatga
    31621 cctactaact cttgggttta tttctattat cgcatattct aaactatgtg ggtttaaagc
    31681 tatttgaacg ttacatccac cttgaacctc tattgcattt attatgtcta ttgatgcctt
    31741 tctaagtagt tgatactctt catcacttag agtttgactt ggagcaacaa ctatactgtc
    31801 tcccgtatga actccaactg ggtctacatt ttccatatta catacagtta tacagtttcc
    31861 atttccatct ctcattactt catattctat ttctttccaa ccttttatac tcttttcaag
    31921 aagaacttgt ccaacaggac ttagctgtag tccatgtgaa agtatttctc ttaattcttc
    31981 ctcagtatca gctatacctc caccagttcc acctagcgta tatgctggtc ttacaactac
    32041 tggatatcct atcttattgg caaactcaag acctgcttct aaatttgtaa ctatatcact
    32101 aactattact ggttgattta tttctttcat tacttctcta aataaatctc tatcttcgcc
    32161 cttttttata gattctatag atgttcctat aacttttaca ttatatttat ctaatatacc
    32221 agcatcatgt aattctacag ctaagtttaa tcctgtctga ccacccatac ctgcaagtaa
    32281 actgtctggt ctttcttttt ctattatttt ttctataaat tctattgtta atggttctat
    32341 atatatttta tctgcaattt ctttatcagt cattatagta gctgggttac tatttactaa
    32401 tacaacttca attccctctt cttttaatgc ttggcaggcc tgtgttcctg aatagtcaaa
    32461 ctctgcagct tgacctatta ttattggccc tgaccctaat actaaagttt tctttatact
    32521 atctaattta ggcataactc tttctcctta tctaaacaat tttcacagtt cttatcttca
    32581 tcatctatac aatcaacttt aattacttta ttttatctta agttcaaatt tactcatcaa
    32641 tacatctatt taatacatct atgttaatta aaccaaactt tttgatttaa gttattcttg
    32701 ttttttagtt agctattcta atgttgttta ttttactaat tctaaaaatt tatcaaaaat
    32761 atagtcatta tcttttggtc ctgggcaagc ttcaggatgg tattgaacac tgtatacatc
    32821 tagcttctca tgtcgcattc cttcaacagt attatcattt aaatttatat gtgtcacttt
    32881 catttgttca ggaacttctg aaacataata accatgattt tgagaagtta taaatacttt
    32941 tccttcttct aaatctttaa ctggatgatt tccacctcta tgcccaaatt taagtttagc
    33001 agtttttcct ccaagagcta aagctaaaag ttgatgtcct aagcatattc caactatagg
    33061 ttttttacca ataagagctt ttatattttc tataacatct tctaagtctt ctgggtctcc
    33121 aggtccattt gacaagaata ttaagtcagg gtttatactc aatacatctt ctggagatgt
    33181 tgtagctgga aatattgtta tatcacatcc acgagctata aatgatctta atatatttct
    33241 ttttactcca aaatccataa cagccacttt tggaccattt ccttttatat gctctacttc
    33301 ttttcttgta acagttctaa ctgcttctgt atttgaaaac ttatccaatt tatgtttaac
    33361 atcttctaat ttactgtctt ctaatgtaat tatacctttc attgttccat tatttctaag
    33421 tatcttagtc aaagctcttg tatctattcc ttcaagtccg ataactttat tttgctttaa
    33481 atattggtct atatcaattt cacatctaaa attacttgga gaatcacttt tctcccttac
    33541 tatgaatccc tttacttgaa ctttttcaga ctctgctgat gataaattta taccataatt
    33601 tcctacaaga ggataagtca tagtaactat ttgaccatag taagaagggt ctgttaaaac
    33661 ttcaccatat cctatcatcg aagtattaaa tactacttct cctacacttt cttctaaata
    33721 tccaaatgcc tttcctataa aaactgttcc atcttctaat attaaccttg ctttcatact
    33781 acagtacctc ctataattct ctttagacaa actaaagaac attaactaaa tataagcttt
    33841 taaatatcta tatctatttt tcacttttac attctagttt tatacttatt tacatttatt
    33901 ttttatcttt ttctattata ctacaaattt cttaaaaaaa agaagttatc tcaaaagtaa
    33961 aaactcctag aaaaaataac ctcttttttt tatttaataa ttaaattctt aaactataca
    34021 atcaacttaa tttctattca gctatattgt aaacttttaa ctcatcttta tttaaatgtt
    34081 tcttcttaac ttctactaaa gcttttagtg tatccaaaga tgtcattatt tcagtagaaa
    34141 attcaatagc tgttcttctt atcttaaatc catctcttgt agagtcattt cctttagttg
    34201 gtgtatttat tactatatca acttgtttat ttcttatagc atctaatatg tttggtctag
    34261 attcttctac tctatttact atatcagcct ctattccatt ttctcttaag ctattagctg
    34321 ttccttctgt agcaacaaaa gtatatccta attctttcat atcttttgct atctctataa
    34381 actcatcttt atcatgatta tttacagtag caagtactac tcctctttca tcagacatat
    34441 gtctacctgc tgccaagaac cctttatata aggcttcttc taaattttct cctacaccta
    34501 gaacttctcc tgtagacttc atttcaggtc ctagacttac ttcaacttta gataatttag
    34561 acattgagaa tactggtact tttactgata ctaattttgg ctctttgtaa actcctgtac
    34621 catatcctaa atcctttaat ttagccccta acatacactt agtagccaag tcaactattg
    34681 gtactccact tactttactt atatacggaa ctgttctact agctctaggg ttaacctcaa
    34741 ttatatataa ttcattttga aattctataa actgtatatt aaccatacca agcacattaa
    34801 ggtctaaagc tattttttta gtgtattcta ctatcttttc ttttatttca tcagatatat
    34861 tttgacttgg atacattgtt gtactatctc cagagtgaac tccagctctt tctaaatgtt
    34921 ccattatacc aggtatcaat atatcttcct tatcacatat agcatctact tctatttctc
    34981 taccagttag atatttatct ataagtactg gatttttatg gtctctatca aatgcatctt
    35041 gtaggtattg agataatttt tcttcgttat aagttatttc cataccttga ccaccaagta
    35101 cataagatgg tctaactaat actggataac ctaactcatt agcaacttca ataccttcgt
    35161 taagtgacca tacacccttt ccttttggtc tatttatatc tagtctctct agtaaatcat
    35221 caaatttttc tctatcttct gctgcatcta tatcatcaaa atcagttccc aatataggta
    35281 tatttttttc atgtaaaaat ttagccaatt ttatagctgt ttgtccacca aactgtagta
    35341 ttacaccttc tggcttttct ttttctatta tacttaaaac ttcttcttct gttaatggtt
    35401 caaaatacag cttatctgat gtatcaaagt ctgtacttac agtttcaggg ttattgttta
    35461 tgattatagt ttctatgtcc atttttctta aagattttac acagtgaact gaacaatagt
    35521 caaattctat accttgacct attcttattg gaccagaacc taatactatc acctttttct
    35581 tatcactaac aactacctca tcatattgct cataagttga ataatagtaa ggagatatag
    35641 catctatctc acctgcacaa gtatcaacca ttttatatgc tggttttata ttgtatagac
    35701 ttctcaattc atataatttt tctggactta tcttcattag gtcagatata cctttatcag
    35761 agaatccctt tttctttaat tcaagaagat agtctttagt taaatcttca attttcataa
    35821 cttttaattt ttcttcttgc tctactatcc atttaaattt atttataaac catttatcta
    35881 tacctgtaat ttgttctatc atttctactt tatagcctct tcttatcatt tcagctaaat
    35941 caaatagtct ctcatcatca ggtactacaa ctcttttctt taattcctca atgcttctct
    36001 cctcagatgg tgtgtgaact aatgaatatt ttcctgtttc aagtgatctt atccctttaa
    36061 gaatagcagc ctcaaagtta cttcctatac tcataatttc accagttgcc atcatcttag
    36121 ttcctaattt tctatttgct tttttaaatt tatcaaaagg ccattttggt atttttgcca
    36181 ccacataatc tatagttggt tcaaaacaag cataagtttt tttagttact gcattttcta
    36241 tctcatctaa agtataacct aaagctattt ttgacgaaac tttagctatt ggatatcctg
    36301 tagcttttga tgctaaagct gatgacctac taactcttgg atttatctct ataactgcat
    36361 attcaaaact atgtggatta agtgcaaatt gaacgttaca accaccttga acttctactg
    36421 catttaatat atctaaagat gcttttttaa gcattgcaca ttctttgtta cttaaagttt
    36481 gagttggagc aacaactata ctgtctcctg tatgaactcc gactgggtct atattttcca
    36541 tgttacatac aactatacaa tttccctttg aatctcttat tacctcatat tctatttctt
    36601 tccaaccttt tatactcttt tcaattaata cttgtccaac aggacttaat tgtagaccat
    36661 gtgaaagtat ttctcttaat tcttcctcat tatcagctat acccccacca gttccaccta
    36721 gtgtgtatgc tggtcttaca actactggat aaccaattgt aagtgcataa tcaagacctg
    36781 cttgtaaatc tgtaactata tcactaacta ttacaggctg atttatttct ttcattactt
    36841 ctctaaatat atctctatct tcaccttttt tgatagattc tactgaagta cctattatct
    36901 ttactccata tttatctagt atgccttttt cataaagttc aactgctagg tttagccctg
    36961 tttgtccacc catacctgca agtaaactgt ctggtctttc tttttctatt attttttcta
    37021 taaattctat tgttaatggt tctatatata ttttatctgc cacttcttta tcagtcatta
    37081 tagtggctgg attactattt attaatacaa cttcaattcc ttcctctttc aaagactggc
    37141 aagcttgtgt tcctgaatag tcaaactctg cagcttgacc tattattatt ggtcctgacc
    37201 ctaatactaa agttttcttt atactatcta atttaggcat aaatttttct ccttatctaa
    37261 atggttttta ctatctgtaa ataatactaa atctatatta atgctaagaa tttattaaat
    37321 atacaatcta aatcttcttt tgttgtgtat tctggaatgt attgaacact atatattggt
    37381 aattccttat gtctcattcc ttctatagta ttgtcattta aatttatgtg agttacttct
    37441 gtattttctg gcatttctga aacattatat ccatgatttt gagaagttat aaataccttt
    37501 ccagtttcta aacatttaac tgggtgatta cctcctctat gtccaaatac aagctttgaa
    37561 gtctttcctc ctaatgccaa tgctaaaatt tgatgtccta aacctattcc tgtcaatggc
    37621 tttttgccta ttaatttttt tatattttca actatatcat ttatatcctc tggatttcct
    37681 gggccattag ataataagat taagtcagga tttatattta aaatttcttc tactgtagtc
    37741 attgctggta ctatagttat atcacagtta caagccttaa gagactctag tacactattt
    37801 ttaacaccaa agtctataac tacaacttta gctccagtac cttttatatt ttcaatttct
    37861 tttcttgtaa cattttttac tgaatctttg ttacaatgct cttctaattt agactgaaca
    37921 tcttgtaatg atacattttc taaagttata attcctctct tagttccatt gtttctaata
    37981 attttagtta atgctcttgt atctattcct tcaagtccta ttaccttatt ttgctttaga
    38041 tatgtgtcta tatccatttc acatctaaaa ttatttgggt tatcactttt ttctcttaca
    38101 ataagtcctt ttacttgcac cttatttgat tcaacatctt ctaaatttat tccatagttt
    38161 cctataagtg gataagtcat agtaactatt tgtccataat aagttgcatc tgtcaatagt
    38221 tctccatacc cagccattga agtattaaat acaacttctc caatagcttc ctttagatat
    38281 ccaaatgctt ttccttcaaa tactgttcca tcttctaaaa ttaatttccc cttcatgtaa
    38341 gctacctccc aaatatttta tctaagcatt ttctatttct cttacaatat taatagctga
    38401 ttctcttgga ttttctgctt ttgttatagg tcttccaaca actaaataat gagcaccttt
    38461 ttttattgca tctgatggag ttacaactct tttttggtct ccaacctctg ctgatttagg
    38521 tcttattcct gggcaaactg ttataaaatc agttccacat gcttctacta ttttatctac
    38581 ttcttgcgct gaacaaacaa ccccatctat tcctgattct tttgccagtt tagctctctt
    38641 tatagctaac tcttctgttg tcatattaca tcctatgtcc tgtaaatctt ggttgcttaa
    38701 tgaagttaaa actgttactc caactactaa tggcttttct atatttaatc tttctgcttc
    38761 ttccctagca attagtgcac attgtctcat tccttccata tctgatacat gtattgtcat
    38821 taaccaaaca ttatctctca ctgcagcttt cactgcactt ttcatagtat ttggtatatc
    38881 atggaattta aggtctaaaa atattttttt ccctttttct ttaagataat ctattgtttt
    38941 accttttgtg gcaacgtatt gctctagccc taccttaaat atgtctacac tatcttctaa
    39001 tctgtctatt agttctttag ctttatcaaa ttcgtcagta tcaattgcaa ctatcaattt
    39061 ttctttacca tttatcattt ttacatctcc tttttaataa agcctaaata atcataaaaa
    39121 aatcctcaca ccaaaagagg cataaggatt ttatctatac ataactctat tcattagcta
    39181 tgagatatct ttcccagtct ctctggacta gtttaaaaga ctttattata tttaaatttt
    39241 tattttatac tcatcaaaaa cctctagaag atttactaga ggttatatac taacattatc
    39301 tataaccctt tagtctctct ggactacttt aaggaattta gctgtaatat ttttctttat
    39361 ttatataact ttatgtatct ataggataat ttaaagtttt atctttttta taattaaacc
    39421 actaattgct ttttatgtca ataagtcttt gaattattct tcatctttat caaacaattt
    39481 tttctcaaaa tatgattctg cattatatat tgcagcaact ggattatgcc cagttactct
    39541 atctttgaca actaaagttg ttataggagc ttccatatat ttcatggcta aagtatcgtg
    39601 accaacacat aatccaagaa ttacattaag gtcaacctta gcttcattta aaaataaagc
    39661 ttgtcctatt ggattgcaca ttacctcatc tgaacacttt gatattgttt gagatgcttc
    39721 tagtccaatt gtactcttag gcattgcccc atttttacat ataacagaaa atacttcaaa
    39781 cccatgatgt tcaaatattt tttgcactgt ttgcatttct ctttttagtc caatacaaaa
    39841 tgctatgcca atctttttat aaccacactt tttagcaaac tctataatct cttttagtct
    39901 agtatattga caatacccct ctgcttcaac taatccagca ttataagcta tttttctatt
    39961 ctcttcttct tcataaagtt gctttgcttt ttgttgtagt tcaatttctc tagttggaca
    40021 tatcttcatt aatttatcca tatttccatt agaacagcct ctaagattac attttccaca
    40081 cttatacata tccaatatcc ccttccaaaa ttttattcat cttgcgattc ttctttttct
    40141 agagttacat tttcttcttg ggtttcttct tctggtttca catgctcgac tacagttata
    40201 aaatatgatt ttcctatttt attccttata ggaagttttt catatgaaac atctatttta
    40261 ttttttatac aagctatatc aaaatgtctt aaggctacac ctaagctaac cttattcata
    40321 tcttcacagt gtttcttagg tctcttttca aataaatgaa gacctcgttc atccttatgg
    40381 aaataccacg gttgagaatt ttttacagat ggagctcttc ttgtcaattc taagatatct
    40441 ttccactttc tattcctatt tatcttattt atcatatctt ttactggctt tctatcaggt
    40501 ctagcatatc tcgtcctaaa caactcttca ttttttgctg gatatccaaa tgctattatt
    40561 atataaggat tttctatttt gttttcatca tcttcttctg tttttattcc agctagataa
    40621 tctaaatcat cttcctcatc ttcttcaaaa ttcttattcc caatatctac aaattccaag
    40681 atatcttctc tctttaagtt tccttccaac cagcaagtag ctattcccaa tgttgtaagg
    40741 cgcaaaacta caccttctgt agcaaatcct atattctgta aatagtcctc acctttgtct
    40801 gatgtaacta ctatataatg aggtgccttt actttacatt ccttccccat caaaaaatgt
    40861 attatatgac ctctatcaac aacatgtgct ttaatattta aatcttcatt taagtattct
    40921 aaatttttac aacttctttt tatttcttcc atcaatggct tttttatctt tttactggaa
    40981 aaatttctta cagattttct ataaaaaatg gcttcataaa gctccattta tgccctccta
    41041 actgaaatct tctgacgtat aaactctata aatttatata aatactttat attttttata
    41101 gttttatttc ctttttcctc ctgccctatt ttgaaattca taagaatatc tactctagtt
    41161 taatatagca ttcaaaaggc ttaaattcta ccttatcaat gtctatacat tagcataatt
    41221 tttttatttg attttctatg ctaatttaaa taacaacact agctattacc tttttaatta
    41281 agctttgcca gaaaaatttt ttttcattta taaatatcta tctcattatt atattataag
    41341 tttttttcgg tattcttgta tagcttttca ctaaaaaagt atttttattt ctactttaat
    41401 attattatca acaaaaaaca tactacttaa ataagtttgt tatcctcata atttgtttta
    41461 attaaaatat tttttttatt tctcaatcta taaagtataa atattttgaa tatgacccaa
    41521 aatctaagta aagttataat attttataag ttgttcaata ttaaaaacat aagtaatgtt
    41581 ataatacttt ataagttatt caatattaaa aatataggag gataaatatg aatttaaata
    41641 gaaatttaga aaaatacgct gaattagcaa taaaagttgg agttaacata cagccaggtc
    41701 aaattctact tataaagtca ccaatagaat gtgctgattt tgcaagaaat gcacttaaag
    41761 aagcatataa atgtggtgct aaaaatgttt atatagagtg gtctgatgaa gaaagtactc
    41821 ttattaaata cttatatgct ccagatgaag catttcatga gttccccaaa tggacagcag
    41881 aacaatatgt agatatagca aaagaaggtg gggcattttt atcagtctat gcccaaaatc
    41941 cagatttatt aaaagatgtt gaccctgaaa gagttgcaaa ttttcagaag gcatctggaa
    42001 aagctttaaa agaatggcgt tcttacactc taactgataa atgtaaatgg agtatagtct
    42061 ctgtgccaac aaaagattgg gcaaaaaaag tgtttccaaa tttatcagaa gataaagcaa
    42121 tagaaaaact gtgggatgct atatttaaat gttcaagagt agatggtcag gaccctataa
    42181 aagcatggga agaacataat gaaaatctta aatctaaaat ggactttcta aataaaaata
    42241 actttaaaac tttaaaatat aaatcctcaa aaactgattt gactctagac ttgccaaagg
    42301 gtcatgtttg gctaagtgga gcatccaaag accctaatgg aataagtttt aatccgaata
    42361 ttccaactga agagattttt ggaatgccac ataagtttaa agtaaatgga actgtttata
    42421 gtacaaaacc tcttgtttat ggtggaaaca taattgacaa tttcttctta acatttaaag
    42481 atggtaaaat aatagatttc tctgctgaaa agggactaga tacactagaa aaacttattg
    42541 aaacggatga aggctctcat tatttaggag aagttgctct tgttccatac aactcaccaa
    42601 tatccaatac ggatataatt ttttataata ctctatatga tgaaaatgct tcttgccact
    42661 ttgcaattgg ttctgcttat aagacttgtc tggaaggtgg aaacaattta aaagatgaag
    42721 aattagatga acatggtgta aatgacagtt taacacatgt agattttatg attggttctg
    42781 ctgatatgga tattattggt gagacttatg atggaaagca aatacagatt tttaaaaatg
    42841 gtaattgggc tttttaacat atgattttaa ctaaaaaggg ctgatggaag ttataccaga
    42901 cttcccagcc ctttttaatg ttgatgataa atatttttta tattaattaa tctcattatt
    42961 atagattaat tcctattgtt ttaaacataa gtatctaaaa cttatattta tattatatat
    43021 aaaatatcct atttagtaaa acctttattt taatttatat gctaaaaatt taactttgct
    43081 atttcaacag cagactttgc atcctttgaa taataatcag cacccatttc ttcagcgtat
    43141 tcttctgtca aaactgcacc tcctacaaat acctttgcat ttatctcatt atctctcagt
    43201 gcctgaattg tatctttcat actttgaaca gtcgtagtca taagtgcact taatcctact
    43261 aattttatat ttctcttttt agcaacttcc actacttctt caatagggac atctttacct
    43321 aaatctataa cttcatatcc ataattttct agcattattt ttactatatt tttcccaata
    43381 tcatggatat caccttttac tgtagcaact attatttttc ctttggatac attattgcta
    43441 cttttactta ataaagtttc ctttattgta tttaatgaaa cttttaccgt ttctgctgat
    43501 tgaatcaatt gtggtaaaaa tatatctcca ctatcatatc tttttcctac tttatcaaga
    43561 gcaggaatta aaatctcatc taatatataa ttttcatcct tctcttttaa aagattcagt
    43621 gttacatttt ttgcttcatc ttttaatcct ctttcaacta aaatatccaa gggcaaatct
    43681 ttatcaatct ttgtagatga atccgatttt tttgaattat ttatattgct atattgattt
    43741 atatagttta tacatccttt atctgtgtta tttaatattt taaaagaatt gatagcttcc
    43801 atcatactat attcatttgg atttataatt gctaaatcaa gccctgcccc taaagctaat
    43861 gttagaaaag aagcattaag tgctttccta tttggaagac caaatgaaat atttgaaaca
    43921 cctaatatag tttttactcc tagtgtcttt accattgtta tagcttttat agtttctatt
    43981 gcttcttctt gttgtgctga aacagttaat gataaacagt ctataaatat atcttttggt
    44041 tttatcccat aagaaactgc tctattaact atcctttttg ctatttcaaa tctttcttca
    44101 gcctttttag gtatcccctt ttcatcaagt gtaagtccaa ccacacatga accatacttt
    44161 ttaactattg gtaatatact ttctaaagac tcctctttgc catttacaga gtttactatt
    44221 gttctaccat tataatatct aagtccttgc tctaaggcct ctacattgga agaatcaact
    44281 tgtaaaggtg tatctactac tgcttgaatc tctcttatta attttggcat tagttttttt
    44341 tcatcaatct ctggaagacc aacatttact ccaagtattt gtgctccagc atttacttgt
    44401 tctaaaccta aatttatagc ataatcaaca ttttcatttt ttaatgcttc ttgtagagat
    44461 tttctacctg tgggattcaa tctttctcca acaactgtag gcgattgtac ttccacaaat
    44521 tttgatggtg aacagactac acatttatca attttctcga tacatccctt tgtaacagaa
    44581 tttatattct cagatatttc ttttataaaa cttggattcg taccacaaca tccacctatt
    44641 atagtagcac caacttcaac gaacttttta accccttcaa aaaattcttt tgcatcaaca
    44701 tcatatatag cctctccatc aactatattt ggaagacctg catttgcttg aaccataaca
    44761 gggactgtag ctcttgatgc tattttttca actattggta aaagttgttt aggtcctaat
    44821 gaacaattaa ctcctattgc atctacacct agaccttcta tagtagccac catacattct
    44881 ggcatacatc cagtaaaact tcttccacct tcatcaaatg tcatagtaca gaaaataggt
    44941 aaatcagagt tttcttttgc tgctaataca gctactttag cttcatataa atccatcata
    45001 gtctctatta ctattacatc aactccagat ttaacgcctt gtagtacttg tcttttaaat
    45061 atttcatatg ctttatcaaa acttaaagta cccataggct ctagcatttc tcctatagga
    45121 ccaatatcta aagctacata tcttggttta gtattatcta cattttctat agcttttcta
    45181 gccaccaaaa cagcattgtc aatcacttct tctacagtat acttactatc taattttagt
    45241 tcattacatc caaaagtatt tgtaagaatt acattcgaac ctgcctctaa gtatgctgta
    45301 tgtatttcta taagtttatc tggattttga agaccaaata cttctggatt ttcacctaac
    45361 tttaaccctt tttgttgaag cattgttccc attgcaccat caaatattaa tatattattt
    45421 ttcagatatt gtcttatttc cacaagagtt cgctcctttt ctatatgtac agtttctata
    45481 gtttttacaa ttttcacacg acttttcttt cttagattta tttattcttg tattagaaat
    45541 acctataata gccactactg actttctcgg tatcataatt ccattagaag taattgttag
    45601 acctatttgt ttttgagcat tcaaaacgtt taatatatct atattttttt ctattggtaa
    45661 atctccatat cctgggctat atcgcatagt tataaattta tcttgcttta aaaaaacctt
    45721 ttctaaatta ttttgaacaa tgtcacacac ttcttctatt gctgttgttc cacatgaatc
    45781 aattattagt ccttttgtta aatttgaata agagtgtcgt cttatttctt tttctatatc
    45841 tatccctata gtagctgcca taattacaca ctcattacat tcttttaaaa gttcatatac
    45901 atctttactc tctaatgtta aatttgttcc ctctaattct acaacattat ctttatttat
    45961 tttaatagga taaatcctag ataaatatct aggatttatt ttatttttag ttatagctac
    46021 acattcatca atagtatatt taaggtcttt atctatctct tgacctctat attgtaaata
    46081 tcttaaaact tcactttgat ttatgcttat atcttctctt ccaattaaat tattctccat
    46141 atatatttaa agaaaatcct ttatctaaaa catcttttgc atattccttt gccccaaata
    46201 aagataagtc tctgtagttt ccacattcta tagctgtagc tgctggcatt ttatctgatt
    46261 caagaacttt ttttaatgct tcttctaaac caatcttaac tgttttggca tctacatctc
    46321 cccatagtat taaataaaat cctgttctac atcccattgg agataagtct attacaccat
    46381 ctaatgtatc tcttaaataa gtagctaaaa gatgctctaa accgtgcata gcagcagttc
    46441 caaaactttc tacatttggc tgtaaaaatc tcaagtcaaa tttagttact ttatctccct
    46501 ttactccatc aagtacacta cactttctta caaaaggagc ttttactttt gtatggtcta
    46561 gcttaaaact ttctactttt tccattattt aatcctccat tatactttaa aatttgttac
    46621 attaattcta aaaaaaactc ttcctatcta ttattgataa gaagagtata ttatttcaag
    46681 tcatctcatc gttgttagca ggaccacctg ataaaaggtt ggtataggat cactgagcta
    46741 actctctccc ctaactcttg ataagtatct tattaaactg acttaaatta tatattactt
    46801 ttttattttt gtaaacactt tattgttata atatttatat cacataatcg tacttttatt
    46861 ttataactaa gctgattgta ttattggcag ttgtacttca aacacagttt gatatttatc
    46921 gcttgaaaca gtaatttctc catcatgtaa atttacaata ttttttgtaa tcgcaagacc
    46981 caatccagaa cctccaacat ttctatttct cgatttttca actctataaa atctatcaaa
    47041 tatatttggt aaatctaaca ctggaattgg ttccccataa tttatcactt ttacaaccgc
    47101 catatcttcc tttttctctg tgactatatc tacataatgc ccatcttttc catatttcac
    47161 agcattagtt ataagatttt caaatgctct taccaattta tttggatcag cttttacaat
    47221 taatttttct tcattaaaat taattctact aaccataaat tcttgtttaa aataaatttc
    47281 aaattgagat actacttgac ttaataactc tactaaattt atttctattt tgtttaattt
    47341 tattgtatta ttttgcattt tagtcaattc aaacaaatca tttataagaa catttaaatt
    47401 tttcgatttt tcatatgcaa tatcaacata atacatcatc tgaacttcat ctttatactt
    47461 accttcttct atcactccta aataacccat tatggatgtc aaaggtgttc ttaagtcatg
    47521 tgacacattt gttattaaat ctgtttttgt ctgctgagct tgtctctctt caatagttat
    47581 atttctaagt tgatggacta tattattgat tttatgtgct agttcatcaa tatcatcctt
    47641 ttctttatcc tttaatatat ctaaatcata ctcaatatct atactttttt ctaagttacc
    47701 ttcatccatt aaatttacag cacttttaat gatttctaat ttttgatttt ttctattagt
    47761 ctttcttata aaatctacaa tttgcttatt tctcttgtac gatatcatgg aataaattgc
    47821 taatgatgtg attgtaaata aaaatggata aaataaatca taccctataa gacttctgaa
    47881 atctcttgct tgatatacaa gttgattaac tacagacata tcactattga catataatga
    47941 ttttattata tacatacttg ttaaaataag cattgaagtt aaagcacagc ttattataag
    48001 atctaatatg ggtcgaaaca tatgatttaa taaactttta tttttcaatt ttatatccta
    48061 ctccccatac agtatgaatt attttttctc catctgtata tttttcaatt ttatccctta
    48121 ttctgctcat atgaaccatt acagtattat tagattggta atatttctct ttccatacct
    48181 tttcaaatat ttcttctgta ctatatactc tgcctttatt atttgctagt aaatataata
    48241 tatcaaattc tcttgatgtc aaaattattt catttccagc cactgttaca ctatgttttt
    48301 ccttatctat aattactact ccaaccttta tgacatcttt atcttcatta ttagcaccac
    48361 taaaataata tgctcttcta atcagcgact tcactctcac agtaagttca agtgggttaa
    48421 atggttttgt caaataatca tctgcaccag tcattatccc ttgtatttta tccatgtctt
    48481 ctgattttgc acttaacata agtattggta tattcaaact ttctctaact tttctacaaa
    48541 cttctatccc atccatttta ggcatcatta tatccaatat cattaaatga atattttcct
    48601 tttttaaaat atctagagcc tcttttccat cttcagcttt aattacatta tatccactat
    48661 ttaaaagata tatctctata aggtctctta tttccttttc atcatccaca acaagaactg
    48721 tattattcat ttttacacat cctaacttaa tctttgtata tagctttatt catataaaat
    48781 tatactatat tttagttagt gtaatctata aatttattaa tttctaaatt tccaatataa
    48841 tacaaattat ttacacattt atattattta ttttgtaaat attcttctaa agttaatcct
    48901 tttgaataaa tttcctcggc agcatcctta ccaacatatc taatatgcca tggttcatat
    48961 gctgtacctg ttatatcttc tttaccttca ggatatctta ttataaatcc aaacttgtga
    49021 gcattttctg ccaaccattt agcttctttt gtacttccaa caaaccatct ttctggattt
    49081 gttaaatcaa tacaaagtcc agtttggtgc tcactgtaac caggctttgc tacatacgca
    49141 tctgcctttt ctcgcccctg agattttacc cttcttgtat aagtatccag ttgagtatca
    49201 taagatctgt atgctgaaga ccctaaaaac tgtattcctt ctgaattagc ttgcttaact
    49261 aaatcttcaa ctgcctttgc aggttctcct gccatttgtt tttcttcctc tgttgcttct
    49321 tcaacaaaag gtatgtttac cttagtaata ttttcaggag tatagttttt gctaattcca
    49381 tttgtcttgt ttaccaataa tatatttgat atactatttg agtgattttt attttgagaa
    49441 tttgcctcaa catcttgttc tgaatcatgt tgagcagcta ctattggatc tttatctttc
    49501 ttaagtaatc tatctttaga tataaataca cttataaata ctactaaaat aatggctcct
    49561 attaatttaa attttttcat aattaaatct tctccttttt gttatgtttg ctataatgtt
    49621 aattttagag tataagactt aagtatttta taagtaaatc ttaaataaat cttaaattta
    49681 atatttttaa aggatggtga taaaatgtct atacaaaaac ttctaagtaa agctcgtaag
    49741 gctatacaag attttgatat gatacaagaa aatgataaaa ttgcggttgg actttctggt
    49801 ggaaaagata gtttaactct acttcatata cttaaaagtt atcaaagatt ttctccacaa
    49861 aactttgaat tgatagccat aacattaaat actggaggtg ttgataattc tccactagat
    49921 aaattgtgta aagaaataaa tgttcctttt tatgaatttc aaactgacat aaaagaaatt
    49981 gtatttgata taagacaaga aaagaatcct tgtgcattgt gtgctaattt aagaagaggt
    50041 gctttgaacg ataatgctaa aaaacttgga tgtaataaag tagctcttgg tcatcataaa
    50101 gatgatgcaa ttgagacatt tttaatgtct atgttttatg agggtagagt aaattgtttt
    50161 tccccaaaga catacctaga cagacaggat ttaacagtta taagacctat ggtttacata
    50221 gaagagtata tgactaagaa aatttcaaaa gattctaact atcctattat cacaaatccc
    50281 tgccctgcaa atggtcatac taggagagag tacataaaaa atcttattgc taatttaaat
    50341 aaagagatgc ctgattttaa aagaaatgta tttggtgctt taaataattc tgagaaattg
    50401 tttatatggg ataaagagaa gataaaaaat tttaaataat aattaaaatt tttaaataaa
    50461 aaagcaagat tgtattaatt gtaaataatc tttatataat ctacacaatc ttactttttt
    50521 atttattata tgttattatc tttaatctat attttaatag ttcttaatag tatttatttt
    50581 gtctaataca ttaattataa cttaaatatt ttatatatta atttaatcta ttaattcatt
    50641 caatctactg gtttaatcca tttttacagt atatacatct acatattata aaaagcaaaa
    50701 ttatattttc taaatatttt atgttagatt ataatattaa attctattat ctctggtata
    50761 ttaaaaaatc taaatggtaa ctttgtactt ccaagacccg aactcacata taaatgattt
    50821 ccatttatgt cataaaaccc tttagtatat ttccttccat atggaggagt aactaatgct
    50881 cccttaatag gtaatcttat ttgaccacca tgactatgcc cagatagaac taaattcatt
    50941 gtatctttac taagcatatc tactaaatct ggttcatgtg ctaacaataa attaaaactt
    51001 ttattatcta tttgactctc cagatatttt atattaggat ttccatttaa tatttcatca
    51061 acacctaata tattaatata tttatcatct tttaatttta tttttttatt ttcatttact
    51121 aaaagattga agttggaatt tttcataatc tgcctataat acctaggaag tttatacata
    51181 taatcatgat tgccaaatac tgaaaatttt cccaacctag cattcatact tgataaaata
    51241 gttgtaattt catctacact tggattttta ttggagtaat caattaaatc accagtaaat
    51301 actattatat ctggattcaa agtgttaatc ttattagcta cttttttgag attcttagtt
    51361 gaataaaaac tacctatttg agtatctgaa atttgaacta cttttacact ttcagattta
    51421 ctctcaattg aatcattttt tatcaatgct ccattttcac ttatattata ttttttcaca
    51481 attaatagac tcggctctat cgcaactgag tatataaaaa tcaaaataaa tattaagata
    51541 aaaaatttta aaaaatactt aatttttgag ttcaaaatat ctacctactt atttattttt
    51601 ttaaactatt tgcattacag actcaacttt gttcattttt ctgtcatgca tttttggctt
    51661 atttgctgaa aaccatttat atgttgctgt aagaccttct tttagtaaca cgtttggtat
    51721 ataaagccca tgttcaataa gcttatttat atcaagatta aagtctatat ttctaaatgg
    51781 gaaatacgtt ctttctctaa actctacttt ttccatatct acatatttta ttataggttc
    51841 tttgccaata atttctccac atgtatatat aaggtcatcc caagaaatta actgtggatt
    51901 tgtcacatta taggcctctc ttacatgagg atttttcatt atgctttcca atacctttac
    51961 caaatcccca atatatataa attgattact aacttgtttt ccttttggta ctggtatctt
    52021 ttcatttttt tctatttttt caaagaaata atactctcta tataaattat tattttcacc
    52081 atatatgtaa gttggtctaa taattatata tggtataggg ctatttataa taaaatcttc
    52141 agcctctttt ttatttaacc catattttcc ccagttttca ttttcacctt tctcattttc
    52201 ttcttttata tttcttccac tatctttata tactgctcct gctgacaata ctatatactt
    52261 ttttaagtta tccatgctta taaaatcaat cagattactt acatcttctt ttgtatatgc
    52321 tgtcatatca tatatgtaat catattttct tcctgtgata atgttttcca tatcttttcg
    52381 aacttttcta tcacaaatta gatgttcttt aaaaccatta taatctattt cctttttacc
    52441 atttgtaagt atatcaattt gatacccaca tttaatcaag cgcttagcaa gtgcagaacc
    52501 tatgaagtcg cttccaccca taattaaaat agatttcatt ttaagtgcat cctcctcttt
    52561 tttaaatgac ttccttaact ataatatcat atttttaaat atgcgacacc attttgtaat
    52621 atttttgtct ataaaagata tttataacaa aatatctttt atagactcta cattttcgac
    52681 aatataagta ggttcacttt cactaatctc ttcaaaagaa ccatacccat acaatactcc
    52741 aatagaatct atacctattt ttttagctcc aattatgtca tactttctat ctccaaccat
    52801 aataacttta tctttatctt ttacattaca taggtctagt acatattgta taacttcatt
    52861 tttattcact cttgtaccat caagattgct acctgctata tatttaaaat atctatctat
    52921 atcaaaatat ctaagtatag tttctgcaaa aactgttggc ttagaagttg ctactaataa
    52981 tattttacca tttttataga gcatttctaa tatctctttc atattctcat aaattttatt
    53041 ttcaaatatc cctttatcag caaaatattc tctatacttt tcaacagctt ctttagcttt
    53101 tttatcttca aatttataat actccttgaa agtatcatgt aatggtggtc ctataaattg
    53161 gtctaagttt tccaaatctt cttttatgcc aaagctattt aaagaatact gaatagactt
    53221 tgttattcct tctttagggt ctgtaagtgt tccatctaaa tcgaataata ctatttcata
    53281 attttttttc atatttcagt cctccatatt tgtaaaaagt aatatcttat atattaagtt
    53341 tatctatttt aaaaagctat agtaatagaa atttctaata ctatagctta agtaccaatt
    53401 aaatcttata tatttatttt aaaaataaat ttaaacagct ctatttaact gttatagctg
    53461 aaactggaca tccttcttcg gcttctttac ataaatcttg taaatctgct ggtatttctc
    53521 cttcaattgc tactgaatgc ccttcatcgc tcatactaaa aacgtctgga catgttccta
    53581 tacatgctcc acaagctaca catacatcct tatcaacaaa tgctttcata ctaaaatacc
    53641 tcccctaaaa ttattatttt ttaattgttg tttccttaga tatttatcca atatatacca
    53701 atttaaacat atatttatta ttttatcact attgtttagt ttattatagt attttcgtat
    53761 ccatgtctat aaacttcact gcttttcatc catgatttta cagtatattg caatcttaat
    53821 tttttattta aaacaagttc attattattg tagtctttta taatatcatt acactcctcc
    53881 attgtaaata ttgtaaaatc accttctcca ccaatcttta ttctgccttt atttccatgt
    53941 aaatcgaaaa tctttgttgg gtattcagtt actttttcta tacacttttc tagggatatc
    54001 ccaagttcca taattttatt tataacattt aaaagagaat agtttacgtc tttcatgttt
    54061 tttatatgca tatcagtact tattaggtca ggctctaaac cttgctttat tgctttttta
    54121 aaaactttaa aatcaaattg gtccactcca tgacatacat caaacaatac tcctctattc
    54181 tttgcattta ttactgattt tcttaatgtg ccagattctt taaggattcc atttgtacta
    54241 tttccatata ccggtgtaac cacatctcct tttcccaaaa tattcattac ttcatctata
    54301 tatgatggat actctcctat atataccact aagggtaaat ttaatttttt agcaacttgc
    54361 tttgatttct taattatatc tataccactt tcattagatt gaaatttact cgcttttact
    54421 tttataccct ttatcttttc tatatttttt tctacaattg actcaacctt gtcaaaattt
    54481 ataacatcta aataagttga ttcattcaat atatttagtc cctcatttgt aacatttaaa
    54541 aaagaatata cttctgtttt acactcatcc atatactttt ttttaaaatc atagtagttt
    54601 gagggaccag ctgtacctgc atcaaatata actgtagaac ctttttcaat tccaattgaa
    54661 tcagaatcca tacctgtagg taattttctc ttataacaat gggtgtgaac atctataaat
    54721 cctggggaaa tatacatatt atcggcattt attatctcga actctttatt tgtaagtaat
    54781 ttttcttttc ttattttctc tttaaggttc aatccaatag catatatttt cccatgtaaa
    54841 accaagatat ctcttttttc aaatttgata ccatctgttg gagatattat tgtcccattt
    54901 cttataagta aatttttcat ttattccaca tcctaattac aatataattt ctctaatagc
    54961 ttttcttaca taaagaaaat aagcctaaaa ataaaaatat tttagactta ttcactatat
    55021 tatactatat taattatatt aaattaaata aaatctttaa tttactttaa gaagcaatta
    55081 agtatttgtt gctcggcttc ttcttcagta agacctaatg tcatcatctt tagtatttgg
    55141 tctcctgcaa tctttccaat agctgcttca tgtactaaaa gagcatctgg atgatttgca
    55201 gcaatttcag gtatagcact aatttgagaa tttcccataa ttattgaatc acattgaaca
    55261 tgtgcagaac aaagggaatc cccaataaca caaggattaa acttttgctt agaattatct
    55321 tgcccaactg tacgagaaac tacttgagca gaagagtttt caccctctaa gataaccttc
    55381 atattagatt ctgcaacttg attaccatga gttaataatt tctcaaatac aactatttta
    55441 gctcctttac ctaggtttgc atccatttct cttttagttg aatctacacc cttaatttga
    55501 attgtttcca tttcacaata tgaatcctca tccatattga caatagtaac tggatttaaa
    55561 attctctttc cttctccatc accttcacca taatgttttt ctacatattt tagtcgagct
    55621 cctttacgta agaaaaatct atgtatacca ttatgttcac tatcatcaca accacagtta
    55681 tgtataccac acccagcaat tataacaaca tctgcatttt ctccaatttc aaaatcatta
    55741 tataccatat cctgtacacc agcctctgtt actattactg gtatatgtac attttctcct
    55801 tttgtatttg gctttactat aatatctatt ccaggtttat cagttttagg aattatagtt
    55861 acattttcag ttgaatgtct ctctactcct tgcccatttt tacgtatatt gtatgctcct
    55921 aatggagttc cacgaagttc agcaactttt tctaaaagat ttaaatctat tttgttcatt
    55981 taatttgcct tcctttctaa ttaattcatg tctttcatta attcacaact tgaattaact
    56041 tgacacatga tttcaggtaa tatagcctct tttgttccat ggctttttac tgaaccatct
    56101 tgtagaacaa ttatttcatc agctaactct aatattcttt cttggtgaga aattatgatt
    56161 atagtctgat tagactcttc atgtattttc ttaaaacttt cattgagttt tccaaagctc
    56221 caaaggtcta tccctgcttc aggttcatca aatatagaaa cctttaaatc tctagcaaaa
    56281 agagttgcta tctcaattct tttcatttcc cctccagaaa gagagttatc aacttcacga
    56341 tttaaatagt cttttgaaca caatccaaca tctgtaaggt attggcaaca tacatcagta
    56401 gacaatggtt ttccatgagc aagtgtaagt aaattttcaa ctgtcatacc ttttattctt
    56461 ggtggttgtt gaaatgcgta tcctattcct ttttttgctc tttctgtaat actaagattt
    56521 gttatatctt ctccatctaa aattatctga ccactcgtag ctttttcaat tcccataata
    56581 agcttagcaa ttgtagattt tcctccacca tttggacctg tgataacaat aagttttccc
    56641 ctctcaaatg aaaggctaac atcatttatt attcctagtt cctcattgtt agactcaaca
    56701 ttaaaggaaa gattttttat ttcaagcata atacccctct tttctataaa atattacatt
    56761 aatatccatt cttttattat atcagtaatt tttatatatc agcaactcta aggagataaa
    56821 atgtatatta aataataaaa caaagttatt gaaaagtaaa aaagatgagt tttatgtaaa
    56881 ctcatctcag aaatttagta tatcaactta tatgtattta aaatttaacc ttctatatac
    56941 tctaatatta ttttttgatt atcttttaac ataatttctt cttttttaga ttctattcca
    57001 ttctttttta tctttacctc agctacaaag gcatcattac cttcaaccat ttctaatagt
    57061 tcatacgctt ttttacgacc tattttagtt gctatatctt ttagtactgc cattttctta
    57121 aacattttat cacctctact caaaatttac acttaatttt taattatata attctaatcc
    57181 tagactagtt tataataatt attgtctcta attatatcag atattgagta aatttaatac
    57241 tttgtaaaat tatttatcct ctctgaccaa ataatcattt ccatcttggt ctttaaaaga
    57301 aaacatcctt ccatatggca tctccattaa ttccccaacc tcaacctcgt tatttgccat
    57361 ttgttcataa gttccattaa tatctcttgt acttaaaatt attgatggat gagatacatt
    57421 tatctctttg ttttgcttca tcattagatt tttatcatac aacacaaatg ttgtaaattc
    57481 atttttactt ggtgctactt ccacccattt catatttgga cccatttcct tttcataagt
    57541 tactacaaag ttcaattttt ctgtccaaaa taactttgca tcctcttgat tatttacata
    57601 gagagttatt tttcctattt tatttatcat aacaataccc acctttatta ttaaataaat
    57661 acctaatatt ttttatattt aataatatac ccatatatat tattttctat agatatatat
    57721 ttctaatatt tatcgccaaa ttatgtaatt ctgctcaata tataatttat aatatccata
    57781 ctattatagc ctttatttat gtaatttaat caccttatat atcatactta taattatgat
    57841 aataactaca taaaaaatca cttctaaata gagttatcca tctaaaagtg atttcatata
    57901 ttctatgcaa ctttgtgttt tagccacttt gttcctctta atcttaaaca atataaagtc
    57961 cctctaacaa gccaatcagt atacatacct atccaaattc ctaacactcc aaattctaat
    58021 acaaccccca atacgtaacc tgtaaaaatt ctaaaaatcc acatacctat tactgcagtc
    58081 atcattgtat atctagtatc accggctccc tttagccctg ctgataatac aaaggatata
    58141 ggccatatta ccatagctaa acaatcactt cgaattaatt gtgttgagat gtcaattaca
    58201 ctagcatttt gagtatacat acttgaaatc cagggtgcaa ttggtataaa tatagctcct
    58261 actataaata aacaaattgt tgcaaattta gttaaatata ataaagtact cttagctcct
    58321 ttaatatctc cacgtcctat atactgtccc accaaggttg tagcagacaa agctaaagca
    58381 ttcccaatta catttattat ggatgcaatt gacattccta ttgcattgga tgcaattgct
    58441 gatgttccca tagtaactat aaatacttga acaatcaatt tacctgcatt aaaaagtagt
    58501 tgttcaactc cagctggtat tcctatatta aatatagact tttgagtttc aacatcaatc
    58561 ttaaatggaa atattttacc catagatata aattcgtttc ctttaaataa agctcttata
    58621 attactatac atccaattat tctagctata gcaatagata tagctgcacc tgttatgcca
    58681 taggatggtg tttgcaaatt tattcctaga ggatttaaat caataccata tataagtata
    58741 tatcccaatg ttacatttac tatattcata aacatagtca catacatagg tttctttaca
    58801 tctccacacc ctcttaaaat accatttgct atttgttgtg tcgcaataaa tggatacgta
    58861 aataatgtaa actctatgta taattttgca tttgatttta ccaattcttc tgcggaacca
    58921 taaaataaat taattacacc agttctaaaa acccacatca atattgttat tgtaaaggat
    58981 aatattactc cagacactag agcctgctta atagtttcat tcaccttttc actatctttt
    59041 tttcctattt gttgagctac aacaacagta gctccaacag atagtgcagc aaatacagat
    59101 ataaatatat tgtttattga atcaaccatt ccaactgcag atacagcttc ttccccaata
    59161 tgacctgcca tcattgtatt aaatactcct aaaagcatga caaacgtctg ctctatcatt
    59221 ataggaattg ctaactttat aacatttttc cttataaaca tccctattcc tcttttccct
    59281 ctttatataa atttaatttt taattagttt atcgaactgt aaattgacaa tgcaaagttt
    59341 agaattgtat tgttcgcatt ataatatact gctttcaaat aatataaatc ttgtttaata
    59401 tcatttgaac acagtatatc tttataatta tcttatgttt attatttttt atggatacca
    59461 catttaaaat atttattaat ttaatataaa tattttccgt tattattaaa agtagctata
    59521 tttcgttaat attgtatcac tatcgtgtag caataacaat aagtacattt tatatatttt
    59581 ttataatatt atttaatcat ccaaactttt accacttttt caatatataa aatattacac
    59641 tttagatgta acaaaatcgc atccatttaa atattgtatt ttatagacta attttaggat
    59701 gtgatacttt ggttaattta aatgcaaata atctaaatgt aaatatggtt tatcctattt
    59761 cttccacagc acccatacgt ttcagaagat atactgtttc atatttagaa aacatggaaa
    59821 atatttattt aactatagca acatactttg atacacttgg tttaggcaca atgaatattg
    59881 acaaagttta tggtcaatgg gcttggttta ctgataatat atatgattta aatctatttg
    59941 tttttgtagg aaattatcct tatcaaattg ctaaaaacag atatgataca tttgtagata
    60001 ttttgccagt agctattact tctattgtca atggagatag agtattttta atttcaaatc
    60061 cttgtttgtt aaattcaaaa attacagtta gatttatatc tagtcatcct actcttaata
    60121 gaacagttga ttatggcaat attagagatt ttatttttta aaactgcaac atgatgtgct
    60181 attaaaaaat accctaaatt taatgatatt attaaataac tagaatattt ttaattggca
    60241 catcatgcct agctattata aattcataat attattttac ttaagataag tactgtattt
    60301 tatctatttg tatattttta tttacctagt ttctcagttc tatatcctat ttctttatta
    60361 gctagcttat aaccttcttg tatcatttct tctctcgtta atgcactccc taataaattg
    60421 tcaatactca gttgctttct atcactaaaa tacttatcca ataatgattc ctctatatct
    60481 tcctgatatg ccaaatttcc ttcatgcatt atatatttta catcaaaacc ttctttattt
    60541 aatacttttc ccaccaagat acttctatga catcttatag gttcttgcat agctcctaat
    60601 aaaactatcc tataacccat ttgacaaccc ttttttaatc tttctattcc gtttaaaaaa
    60661 atatcttctt ttgctacttt ctcaaaatct gcataacctt cttgcgtata tacatcttta
    60721 ttagttcttt tagctccaaa ttcttttccc atgtatatat ataaaaatcc ggaatttcta
    60781 agagattcgt taaatgcctc tttattgtat tgaatattat atttagaata tggagtttct
    60841 ctaatgtcaa ctacacaatt tatgtcatat ttttttatca tattaataag cttatcatat
    60901 ggataatttg aatgtcctat tgcgaatatt tccatataaa caccctccta ttctttgaaa
    60961 ttagtatcta tatatgtaga tacccgattt acttaaaatt aaataaagta ttactttaaa
    61021 tacccaatat ctttttttct tgatattgta tattttttta ctttatatcc ttaaaaaaat
    61081 atacaacttt atatataaaa catc
//
LOCUS       DAYAOO010000014        57673 bp    DNA     linear   BCT 12-OCT-2024
DEFINITION  TPA_asm: Clostridioides difficile isolate ST8-SSI-h139-18
            SAMN40601845-rid21577343.denovo.014, whole genome shotgun sequence.
ACCESSION   DAYAOO010000014 DAYAOO010000000
VERSION     DAYAOO010000014.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN40601845
            Sequence Read Archive: SRR28438827
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 57673)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 57673)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-MAY-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-MAY-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002157583.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002157583.1
            Genome Coverage       :: 163x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/11/2024 16:19:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 4,038
            CDSs (total)                      :: 3,963
            Genes (coding)                    :: 3,930
            CDSs (with protein)               :: 3,930
            Genes (RNA)                       :: 75
            rRNAs                             :: 6, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 60
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 33
            CDSs (without protein)            :: 33
            Pseudo Genes (ambiguous residues) :: 0 of 33
            Pseudo Genes (frameshifted)       :: 7 of 33
            Pseudo Genes (incomplete)         :: 25 of 33
            Pseudo Genes (internal stop)      :: 11 of 33
            Pseudo Genes (multiple problems)  :: 8 of 33
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..57673
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN40601845-rid21577343.denovo.014"
                     /isolate="ST8-SSI-h139-18"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Denmark"
                     /collection_date="2018"
                     /collected_by="Statens Serum Institute"
     gene            179..1375
                     /locus_tag="ACGI5H_000989"
     CDS             179..1375
                     /locus_tag="ACGI5H_000989"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419109.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetate/propionate family kinase"
                     /protein_id="HFG9696713.1"
                     /translation="MKILVLNCGSSSLKYQLIDMNNEEVLCIGLVERIGIEGSILKHE
                     KAGRDDKYVVEQPMKDHKDAIALVLEAVAHPEFGAVKEMKEIDAVGHRVVHAGEKFAT
                     SVVITPEVEEALKECIDLAPLHNPANIMGIDACKAILPDVPMVGVFDTAFHQTMPKSS
                     YLYGLPHELYTKYGVRRYGFHGTSHNYVSQRAAEILGKDIKDLKIVTCHLGNGASIAA
                     VDGGKCVDTSMGFTPLEGLIMGTRCGDIDPAILPFLMRKEGLDADGLDKLMNKESGVY
                     GMTGISSDFRDIEDAAKNGDERAQATLEAYVKKVQKYIGAYAAEMNGLDVVVFTAGVG
                     ENGKAIRADIASNMEFLGMKLDKEANDVRGKETVISTADSKVKMLLIPTNEELMIARD
                     TLRLVK"
     gene            1468..1992
                     /locus_tag="ACGI5H_000990"
     CDS             1468..1992
                     /locus_tag="ACGI5H_000990"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419111.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF177 domain-containing protein"
                     /protein_id="HFG9696714.1"
                     /translation="MKVSIEKINRKETDKIDLNFCEKIDTISYCDEIYKLVSPVNLKG
                     KVSKTNKGLYLDIDVNFTIVDNCSRCLKEVEIPLEYSIQGFLVKEEDYDEDEFEEFDP
                     FIFDGEEIDLIDIIEQTLDFNVPHKVLCSENCKGLCQVCGANLNEEECSCSEITNDEE
                     YIDPRFAKLKDLFN"
     gene            2017..2193
                     /gene="rpmF"
                     /locus_tag="ACGI5H_000991"
     CDS             2017..2193
                     /gene="rpmF"
                     /locus_tag="ACGI5H_000991"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419113.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0015934 - large ribosomal subunit
                     [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L32"
                     /protein_id="HFG9696715.1"
                     /translation="MAVPKRKTSKSNTKMRRAANSKMEATGFVSCPQCHEPKLPHRVC
                     PDCGYYKGKEVVSK"
     gene            2400..2957
                     /gene="fapR"
                     /locus_tag="ACGI5H_000992"
     CDS             2400..2957
                     /gene="fapR"
                     /locus_tag="ACGI5H_000992"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419115.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0045717 - negative regulation of fatty acid
                     biosynthetic process [Evidence IEA];
                     GO_process: GO:0045892 - negative regulation of
                     DNA-templated transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="transcription factor FapR"
                     /protein_id="HFG9696716.1"
                     /translation="MKKKSKAQRQKELIDMLKTDPFYTDEELSSLFDVSIQTIRLDRM
                     SLNIPELRERVKSIAETQSSKVKTLGVKEITGEIIDLSVGRLGISMLEVTQDMIYSKT
                     NTLKDTYIFSLADSLAMAIIDAPKVIMRVANVKSFKLIEQQDRLIAKAEVYRNIDKKH
                     YVKVVINNKAQEQIFRGKFIFEELD"
     gene            2968..3990
                     /gene="plsX"
                     /locus_tag="ACGI5H_000993"
     CDS             2968..3990
                     /gene="plsX"
                     /locus_tag="ACGI5H_000993"
                     /EC_number="2.3.1.274"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419116.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0043811 - phosphate:acyl-[acyl carrier
                     protein] acyltransferase activity [Evidence IEA];
                     GO_process: GO:0008610 - lipid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate acyltransferase PlsX"
                     /protein_id="HFG9696717.1"
                     /translation="MKIVIDGMGGDNAPKSNVEGAVNAIKEYQVDLIITGDKDLLEKE
                     FSNYEFDRNKLEIVHTTEIIENEDKPVKAIRSKKDSSMVVALNLVKEGKADAIISAGN
                     TGALLAGGLFVVGRIKGIDRPCLCSAIPNVKRGMTLIADCGANADCKPKNLVEFAAMS
                     NIYSRKVLGLENPKVALANVGLEEGKGNDLVKRSYEEIKKLDLNFIGNVEAREVINAY
                     TDIIICDGFTGNILLKSAEGVALSVMSLIKETFMASTKSKIGALLIKDDLRKLKSFID
                     YSEYGGAPLLGLNGGVIKAHGSSDAKAIKNAINQGIKFSKGKVVEDINQFISKYNEEN
                     KNNEDE"
     gene            4016..5002
                     /locus_tag="ACGI5H_000994"
     CDS             4016..5002
                     /locus_tag="ACGI5H_000994"
                     /EC_number="2.3.1.180"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438099.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004315 - 3-oxoacyl-[acyl-carrier-protein]
                     synthase activity [Evidence IEA];
                     GO_function: GO:0016746 - acyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:0033818 -
                     beta-ketoacyl-acyl-carrier-protein synthase III activity
                     [Evidence IEA];
                     GO_process: GO:0006633 - fatty acid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="beta-ketoacyl-ACP synthase III"
                     /protein_id="HFG9696718.1"
                     /translation="MNTKAGILGVGSYLPEQSYDNFHFEKIMDTSDEWISTRTGIKER
                     RFAKESEATSDLASKAALKAIECAKLNVEDIELIILATITPDMSLPSTACIVQDAIGA
                     VNATAFDISAACSGFVYGVTIAKQFVETGCYKNVLVIGAETCSKFLNYDDRTTAVLFG
                     DGAGAAVIGPVNEGGILSTHMGSDGKGKDCLKVPAGGSRLKASKETVEANLHTIEMAG
                     SDVFKFAVRKMAETSLRALEKANLNTTDIDYLVPHQANIRIIQASSKRLELDMKKVYV
                     NIDKYGNMSAASIPVALDEAYREGKIKKGDNVVLVGFGGGLTWGASVVKWTL"
     gene            5111..6040
                     /gene="fabK"
                     /locus_tag="ACGI5H_000995"
     CDS             5111..6040
                     /gene="fabK"
                     /locus_tag="ACGI5H_000995"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0018580 - nitronate monooxygenase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="enoyl-[acyl-carrier-protein] reductase FabK"
                     /protein_id="HFG9696719.1"
                     /translation="MNKICKILNIKYPVIQGGMAWVATASLASAVSNAGGLGIIAAGN
                     APKEAIKKEIVECKKLTDKPFGVNVMLMSPFVDDIIDLIIEEKVQVITTGAGNPAKYM
                     DRLKEAGTKVIPVVPTIALAQRMEKLGATAVIAEGTEGGGHIGELTTMVLVPQVADAV
                     NIPVIAAGGIVDGRGIAASFALGASAVQVGTRFICSEECSVHSNYKNLVLKAKDRDAI
                     VTGRSTGHPVRTLKNKLSKEFLKMEQNGATPEELDKKGTGALRFATVDGDIEKGSFMA
                     GQSAAMVKEITPCKEIIEAMVNQAREIMPAIEL"
     gene            6056..7006
                     /gene="fabD"
                     /locus_tag="ACGI5H_000996"
     CDS             6056..7006
                     /gene="fabD"
                     /locus_tag="ACGI5H_000996"
                     /EC_number="2.3.1.39"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902293.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004314 - [acyl-carrier-protein]
                     S-malonyltransferase activity [Evidence IEA];
                     GO_process: GO:0006633 - fatty acid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ACP S-malonyltransferase"
                     /protein_id="HFG9696720.1"
                     /translation="MGKVALVFPGQGAQYVGMAKDLYENNAVAKSVIDEASDALNMDL
                     KNLMFNGNEEELSKTENTQPAMVTHSVAVLKAVQAQIDLKYNACLGLSLGEYSALVAA
                     DAIDFKDAVCLVKKRGKFMQETVPAGVGAMAAVLGLDRNVLENVVKDIQGGIVEVANY
                     NSPGQIVISGENEKIEEAMVKCKEAGAKRAVKLNVSGPFHSSMLKEAGVKLASELEKV
                     NITKPKVDVVANVNADYYKNEGKDLLIKQVSSSVLWEDSIERLLNDGYDTFIEMGPGK
                     TLKAFIKKIASNKKANVNIYNIDGIDSLNEFVQNYRNGEI"
     gene            7006..7755
                     /gene="fabG"
                     /locus_tag="ACGI5H_000997"
     CDS             7006..7755
                     /gene="fabG"
                     /locus_tag="ACGI5H_000997"
                     /EC_number="1.1.1.100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888925.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004316 - 3-oxoacyl-[acyl-carrier-protein]
                     reductase (NADPH) activity [Evidence IEA];
                     GO_function: GO:0051287 - NAD binding [Evidence IEA];
                     GO_process: GO:0006633 - fatty acid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="3-oxoacyl-[acyl-carrier-protein] reductase"
                     /protein_id="HFG9696721.1"
                     /translation="MINLTGQVAVVTGGSRGIGKEIAKKLASFGADVVINYTSKEDEA
                     LKTKNEIESMGVKCTSIKCDVSKFDEVNQMIDSVVSEFGKIDILVNNAGITKDGLLMR
                     MKEEDFDRVIDINLKGVFNCTKAVTKPMMKKKYGRIINMTSVVGIMGNAGQTNYCASK
                     AGVIGFTKASARELASRNININAVAPGFIETDMTKVLSDDVKESTLANIPKKSYGKPE
                     DVANAVAFLVSDMSSYITGQVINVDGGMVMQ"
     gene            7809..8033
                     /gene="acpP"
                     /locus_tag="ACGI5H_000998"
     CDS             7809..8033
                     /gene="acpP"
                     /locus_tag="ACGI5H_000998"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419132.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000036 - acyl carrier activity [Evidence
                     IEA];
                     GO_process: GO:0006633 - fatty acid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="acyl carrier protein"
                     /protein_id="HFG9696722.1"
                     /translation="MFNKVVEIIIEQLGVEDKEITMETSLMKDLEADSLDAVEIIMAL
                     EDEFGIEIPDTEAENFKSIGDIVKYIEANK"
     gene            8062..9300
                     /gene="fabF"
                     /locus_tag="ACGI5H_000999"
     CDS             8062..9300
                     /gene="fabF"
                     /locus_tag="ACGI5H_000999"
                     /EC_number="2.3.1.179"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438103.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004315 - 3-oxoacyl-[acyl-carrier-protein]
                     synthase activity [Evidence IEA];
                     GO_process: GO:0006633 - fatty acid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="beta-ketoacyl-ACP synthase II"
                     /protein_id="HFG9696723.1"
                     /translation="MNKRVVITGLGCVTPLGTGKEEFWSNIKSGVSGIDKITNFDAST
                     YQTQIAGEVKNFHPEEYISKKELKRLDKFAQFAIVSAKLAVEDANLDLDKVDRERFGV
                     IIGSGIGGVEAIETQHKILLEKGNKRVSSLFVPMMIGNMAAGQVSIFLGAKGPNTNVC
                     TACASGTHSIGDAFKVIQRGDADLMVAGGSEAAVTGLAFAGFCNMKAMSTRNDDPKTA
                     SRPFDKDRDGFVMGEGAGIVILEDLEHALARGAKIYAEVVGYGLTADAYHMTTPAENG
                     EGAARSMNMALKDGNVPLEEVDYINAHGTSTYYNDLYETMAIKTVFGEKAYDLCVSST
                     KSMTGHLLGASGAIEAVVCAMSIEDSFVPPTINIQEVGEDLDLDYVPNQGKEKNIRYA
                     LSNSLGFGGHNATIVLKKYV"
     gene            9526..11244
                     /locus_tag="ACGI5H_001000"
     CDS             9526..11244
                     /locus_tag="ACGI5H_001000"
                     /EC_number="2.7.7.65"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892922.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0009975 - cyclase activity [Evidence IEA];
                     GO_process: GO:0009966 - regulation of signal transduction
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="diguanylate cyclase"
                     /protein_id="HFG9696724.1"
                     /translation="MNFRLPKKRLPKKIIFICIILISIILFIKYDQNGLKEREIINKG
                     KYMSESLVADKEYDEAKKVVKTSFESIPEKKYNKVYNEVWDMLKTISYVPDGTKIVID
                     SLEKMRESDVKLSDECRFNIEKRLASVYIMDNNYSKAVDLTVKSIKLAEKLGNNYEKA
                     RLDVDLASIFLKIGGYETGEKLIKDSFKIDIDEGEKNGMVRLYAIINLAEIYVEEGEY
                     DKAIEISSRIKDYKKFVNTDNYNDFDIMASIMQSNAYVGKNNIQKAKTFLEKADYLIK
                     SDRTVYILDKDMYYYMAMGNLEYKSENYNSAIDNYKKSLEISTKRKLTQEKIKNLNKI
                     LNIYEKQGNIESLNEYQKMLINEYKENKSIRDSETSFYIIDKVSNESKLFEKTKKEIK
                     YYKILFTVILIAILGSTFLYNRLKYFKAQNLHDGLTNVYNRKSFDIMYEKYREKDDNF
                     ALVMIDIDNFKLINDNYGHKFGDTVIKGITNTICVMLEQDDKVFRYGGEEFSVLIRNK
                     SGDEVADIIDSIRVAIANKKWNDDVTVTISAGVAHVSDSKDVLEEADKNLYKAKQLGR
                     NKVVYK"
     gene            11275..13275
                     /locus_tag="ACGI5H_001001"
     CDS             11275..13275
                     /locus_tag="ACGI5H_001001"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018112784.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0008134 - transcription factor binding
                     [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sigma 54-interacting transcriptional regulator"
                     /protein_id="HFG9696725.1"
                     /translation="MKQSIAIVTDKITKLSSFLEENIRLVLGNYIDINHYYLEVLKEN
                     DKIQGDFVLVMNDDRLNSMRKHLVQDSKIIVIRRTLKENEIYGLFSIPNGTEVLVVND
                     TKETTLETISLFYKIGVKNLKFTPYIEGKIYKNIDIAITPGVKGKVPSYINKVIDLGN
                     RYIDISTFIEIINGLRIDVKEIRKNLMAYSESLISLDNGVKDNYRQLFLKIEEQDVIL
                     NLSKDGIIFTSADGIINTFNKEALKILGINENPQGKNIEDIISEDLNILLEDKEIIDE
                     VVFTNKKYINVNKKSIFSMGNKAGIYYNLQEITYIKKLEQNLTNKLREQGQIARYTFK
                     DIKTKNKNMVKCVELAKKISKSDLSVLIIGESGTGKELLSQSIHNDSNRSNQPFIAVN
                     CAAVPDSLLESQLFGYEKGSFTGALREGKKGLFELANNGTIFLDEIGDMPPLLQTKLL
                     RVLQEKQVMPIGSHNVINIDVRVIAATNKNLLKMIREGKFREDLYYRLNVLPIDVPSL
                     RNRKEDIITLMNFFLKNNIRLSPEVITILEKYNWPGNIRELQNVASYVSLMCDSMVFR
                     DDLPPYIRVECANNYEDGFGYTRKEFEEILRILYERRESSSGIGRGFIIEKLIQEGIE
                     ISESKVRKVLSYLSECGYISSKSGRGGSQITSEGIKLYNNIN"
     gene            13626..13871
                     /locus_tag="ACGI5H_001002"
     CDS             13626..13871
                     /locus_tag="ACGI5H_001002"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419141.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003674 - molecular_function [Evidence
                     IEA];
                     GO_process: GO:0008150 - biological_process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR03905 family TSCPD domain-containing
                     protein"
                     /protein_id="HFG9696726.1"
                     /translation="MKYKTTGTCATEIEFEVKENKVTNVNFIGGCDGNLKGLKVLVEG
                     MNIEDVIQKLKGIECKTKPTSCPDQLSLALENYMNIK"
     gene            13906..14631
                     /locus_tag="ACGI5H_001003"
     CDS             13906..14631
                     /locus_tag="ACGI5H_001003"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438111.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="gamma-glutamyl-gamma-aminobutyrate hydrolase
                     family protein"
                     /protein_id="HFG9696727.1"
                     /translation="MKPIIGILGNLIIMENGMFPGLERSYVNNDYINAVLKGGGSPVI
                     IPVNTDKEVIKKQIEMVDGVLISGGWDINPQLYGEETREETTFIYPEVDEFDLIAISI
                     ALELKKPILGVCRGLQILNVSLGGTLYQDNNLIEGSYIKHTQSSKRHVATHKVDVKEG
                     SILEGILGKQLLTNSYHHQSVNQLGKGLKAIAYSKDGIIEAIEKEDENFVVGVQWHPE
                     MMVDYCDKMEKLFKYFINICSNL"
     gene            14653..15966
                     /locus_tag="ACGI5H_001004"
     CDS             14653..15966
                     /locus_tag="ACGI5H_001004"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419145.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="APC family permease"
                     /protein_id="HFG9696728.1"
                     /translation="MNEKNKMGLISIILLGINAVVGAGVFLLPGDAMKSFGVASIFVY
                     IFDMLLVLSMAFCFAEVAGKFNKNGAAYVYTKEAFGDFCGFEVGLMKWVIGCISWGAL
                     IVGFPTSLSAVWAPAGEPHIQKIIIVAMIVGLTIINLLGVSLSKIVQNVITVGKLIPL
                     ILFIGIGIFFIKGVNFTSSTMVPPGAGATEFGAAALLMFYSFTGFESIAVAAEDMENP
                     QKNIPIAIISVIVIASIIYILNQVVCVGILGDSLSSTSTPVADAARICFGNMGAGLVT
                     FGTLVSVGGICMCGAFVNPRSCVALADDKMLPRIFARKDKKGTPYVAIIATMLITIPI
                     ALSGSFAELAAISAVARFIQYIPTSLSVLVFRKKRPELVGTFKTPFGAVIPLIAVCVG
                     TWLLFQASMHQLIMGLGALAIGVPLYFIMKSYNRKIYGENLKKIV"
     gene            16172..16711
                     /locus_tag="ACGI5H_001005"
     CDS             16172..16711
                     /locus_tag="ACGI5H_001005"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905353.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetyltransferase family protein"
                     /protein_id="HFG9696729.1"
                     /translation="MPTITLKNGVDVLIREGVREDAQSIIDFYNEVGGETHFLSFGKD
                     EYKISLEEQENAIESAKASDNSVKLIAFIDGEIVGIATIDSNQKAKGKHVGVLGIVVK
                     EKYWGIGLGKRLMLDLIEWCKSNGITKKITLVTNEENYNAIGLYKKVGFEVESILKKE
                     CYYNGVYTDLIGMSLLLGI"
     gene            16800..18785
                     /locus_tag="ACGI5H_001006"
     CDS             16800..18785
                     /locus_tag="ACGI5H_001006"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428429.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fructose-1,6-bisphosphatase"
                     /protein_id="HFG9696730.1"
                     /translation="MKNLCKISDDYLNSKLKYLKLLSKQYPSISKASTEIINLEAILN
                     LPKGTEHFITDVHGEYEPFVHVLKNGSGVIKRKIEELFSNTIRDSEKKMLATLVYYPE
                     QKLDLIIKQEENIDDFYRINIYRLIELCKYASSKYTRSKVRKLLPENFKYIIEELLHE
                     HVKSEHKEEYYKSIVETIVDIGIAKEFIIAISTVIQKLVVDRLHVIGDIYDRGPRPDI
                     IVDKLIEHHCVDIQWGNHDILWMGAASGEKTCIANALRISARYANLDIVEDIYGINLL
                     PLATFAIEMYKDDPCKEFIPKVNDQSVTTTEKSLMAKMHKAISIIQFKLEGEVIRRRP
                     EFEMEHRLLLNMINYDEGTINLKGKTYKLKDTYLPTIDKKDPYKLTMEERNVIDKLVS
                     SFRGSEKLQKHVSFLFSKGSIYLKANSNLLIHGCVPLNEDGSFMSMNIMGKEYKGKAL
                     MDKMESLAREGFFFKDKAEEKLYGMDIMWYLWTGKCSSLFGKDDMTTFERYFIAEKET
                     HKENKNPYFKLRENEMACKRLFEEFDLELDESHIINGHVPVESKNGESPIKANGKILV
                     IDGGFSRAYQKTTGIAGYTLIYNSRTLQLVSHEPFNSAEEAIANESDILSTTVVVEHK
                     AKRKMVRDTDEGIKIQEEIEDLKLLLMAYKKGLIKEM"
     gene            19009..19977
                     /gene="spoIIIAA"
                     /locus_tag="ACGI5H_001007"
     CDS             19009..19977
                     /gene="spoIIIAA"
                     /locus_tag="ACGI5H_001007"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896114.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003674 - molecular_function [Evidence
                     IEA];
                     GO_process: GO:0030436 - asexual sporulation [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="stage III sporulation protein AA"
                     /protein_id="HFG9696731.1"
                     /translation="MNKLSDEIINSLSTTIREKVEKVSNNNLNIEEIRLRSQKPLILN
                     ANSKDYFYNQKTMTLDLNQQNSYVVTREDVEQTFQIICKYSIHSFMDDIKKGFITLRG
                     GHRVGLVGKAIVEDGQVKNIKHISSLNIRVSREIIGCSDKILSHIIKGKNQINNTLII
                     SPPQCGKTTLIRDIVRNLSNGNEDYGFKGLKVALVDERNEIAGAYLGVPQMDVGIRTD
                     IIETCPKDLGITMLLRSMSPNVIVTDEIGSEKEIKALYTALNGGIGLITTVHGDSIED
                     IQNRKELNRLLDKELFKKVIILSAKRGAGTIEKIYDLEEKRWYFAN"
     gene            19967..20488
                     /locus_tag="ACGI5H_001008"
     CDS             19967..20488
                     /locus_tag="ACGI5H_001008"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419153.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="stage III sporulation protein AB"
                     /protein_id="HFG9696732.1"
                     /translation="MQIKIIIIAFLIGSSYLIGEQIYKTYTRRHKQLNDLIRVLEILR
                     MDLSFGLYTLEEIFNRIGGNKEFCFWKFFYQISEGLHNEQSKTLEIIISENIDVLSKE
                     TYLGNKEIEELKNLILTLGKSDIESQQRMIDLSIENLKKQTYETKEDINKKGVLYKKL
                     VTFIGIGICIILI"
     gene            20505..20702
                     /gene="spoIIIAC"
                     /locus_tag="ACGI5H_001009"
     CDS             20505..20702
                     /gene="spoIIIAC"
                     /locus_tag="ACGI5H_001009"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018589775.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003674 - molecular_function [Evidence
                     IEA];
                     GO_process: GO:0030436 - asexual sporulation [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="stage III sporulation protein AC"
                     /protein_id="HFG9696733.1"
                     /translation="MEISLILKVAGVGILISVLNMILEKTDRKDWAGLTTLAGVIIVL
                     GMVITEISDLFNTVRTMFQLY"
     gene            20727..21104
                     /gene="spoIIIAD"
                     /locus_tag="ACGI5H_001010"
     CDS             20727..21104
                     /gene="spoIIIAD"
                     /locus_tag="ACGI5H_001010"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419158.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003674 - molecular_function [Evidence
                     IEA];
                     GO_process: GO:0030436 - asexual sporulation [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="stage III sporulation protein AD"
                     /protein_id="HFG9696734.1"
                     /translation="MQLIGIAIISTTLCLVIKKDRPEIANFIAIITGVIILLSVMFKL
                     NFIVDSIQDLANKANIPTMYISLIIKLIGIAYLMEFAIQLCKDCGEGNIASKLEFGGK
                     IIVMSMSFPILLSIVEMVVNIIP"
     gene            21189..22394
                     /gene="spoIIIAE"
                     /locus_tag="ACGI5H_001011"
     CDS             21189..22394
                     /gene="spoIIIAE"
                     /locus_tag="ACGI5H_001011"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428423.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003674 - molecular_function [Evidence
                     IEA];
                     GO_process: GO:0030436 - asexual sporulation [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="stage III sporulation protein AE"
                     /protein_id="HFG9696735.1"
                     /translation="MKKRFLPMIIGFLFTFFFVNIFAIMIFANEVPSSEDKEYGETKN
                     SIDKYIDGQLDKLDINEIQDYINKEIVINDVNLKSFVKDLISGEKNILDLFNKDGLKI
                     LMFDEFKASLKVVAVILVLALLSSILKSLENSFSSGAVSQIATYIIFITMVSLTLIGF
                     KDVLQICYDAIDHTVGLMQVIMPILITFLLLIGFPITSTTLNPIFIGGVTFINVFFKN
                     FLFVSITVAFGILIINNLSKNIRLKRFFSFVKQINYVSIGAMFTVYLGLVSIQGLYVT
                     SFDKFSVKTAKFAIGNFIPVVGGFVSDSVDILLSSSQLIKNIFGGIGLILLVGICLLP
                     VIKILSVIVVYKLAAIIVEPVGEDGISNFLNEVANLMIIMLASVIAITVMFFVTVAIL
                     TSISVVSQG"
     gene            22454..23071
                     /locus_tag="ACGI5H_001012"
     CDS             22454..23071
                     /locus_tag="ACGI5H_001012"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428421.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="stage III sporulation protein AF"
                     /protein_id="HFG9696736.1"
                     /translation="MLEGIKAWIVSVLIGAFIVNIVDMILPSSKIKPYVNLVLNFMFV
                     FIVITPVVGFFSKDMSLEDRILKSMGNYNKQYVDSTNALAKETGNNSLSKGYEDGLKE
                     VLKLKLDEYGYDLEDIELNGANINNIKIKEKNNSAKSNNSSNEENKNNSTKREEENIN
                     SNDKENSKQVFKKGTEYGLNLNEEKLKNDLIKVLDVSIEDIQIDK"
     gene            23083..23637
                     /locus_tag="ACGI5H_001013"
     CDS             23083..23637
                     /locus_tag="ACGI5H_001013"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419164.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="stage III sporulation protein AG"
                     /protein_id="HFG9696737.1"
                     /translation="MLKNLNDKDKRKVYSLITIAGICVVSLVLLSCFPSSKSDKQVGK
                     TETNKNAEKQVTKEQEKDDLESKLTAILSKIDGAGDVDVMVTFESSEEIQPAFNSNNT
                     TETTEEKDAQGGERTVTTSSENKTMITSNSSDPVVIKTTEPKIKGVIVVASGASDPSV
                     KETLYSAVQTSLQVAGHQVEIYSK"
     gene            23664..24353
                     /locus_tag="ACGI5H_001014"
     CDS             23664..24353
                     /locus_tag="ACGI5H_001014"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888947.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SpoIIIAH-like family protein"
                     /protein_id="HFG9696738.1"
                     /translation="MKFNYKGRGFVIITLTAMLVVVGTVNYQLSKKSLLETSKEFKAY
                     EEAQLQKNTDESDSSKTEDSSNVDKQDGKESADIDIVDSKASKVKEKATETSKEIKAQ
                     LSSEKNMKKASYILDMKMNREKQRNELVQDLNEMINNPSTTEESRKEASNMKLNIVKI
                     QEKELQIENLLSTKGYEEALVYISDNKVNVVVNEAKLEKKDAAKIFDLVAEQANVKYE
                     NIKLTNNNSNK"
     gene            24463..24825
                     /locus_tag="ACGI5H_001015"
     CDS             24463..24825
                     /locus_tag="ACGI5H_001015"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419170.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp23/Gls24 family envelope stress response
                     protein"
                     /protein_id="HFG9696739.1"
                     /translation="MEDNKFGQVKISNDVIATIAGLAALEVEGIETTATLTDKLLKNN
                     GVKIQIEEEDVNLDVMVTIKYGMSIPDTAFKVQENVKNTVETMTGLKVSQVNIHIQGI
                     SFKKDKVDKEEAKATKKN"
     gene            24910..25416
                     /gene="nusB"
                     /locus_tag="ACGI5H_001016"
     CDS             24910..25416
                     /gene="nusB"
                     /locus_tag="ACGI5H_001016"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428415.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0006353 - DNA-templated transcription
                     termination [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antitermination factor NusB"
                     /protein_id="HFG9696740.1"
                     /translation="MKKDRAQKSTTREYIMKLIYQININKEDFETLEDKVDNFLKDNS
                     EHIINRYKELALQYSKNTNLKLEDTEIEDVIDKKYINTVCKALKENHDKIDELINKHA
                     KNWTVDRMPKVDVSILRLSVCEILYLDTPNKVSINEAVELAKIYCDDKSPKFINGILG
                     SVVDEIGK"
     gene            25400..26470
                     /locus_tag="ACGI5H_001017"
     CDS             25400..26470
                     /locus_tag="ACGI5H_001017"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018112785.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="O-sialoglycoprotein endopeptidase"
                     /protein_id="HFG9696741.1"
                     /translation="MKLGNNIIIGIDTSCYTTSIAAISLDKKVIFNEKIMLEVRDNSK
                     GLRQSEAVFQHINNLGILSDRIKSFKDKFNVEGVCSSKKPRPVENSYMPVFNVGHNFG
                     KLLSSIYGCRFYETTHQENHIEASLLNSKLKNNNKFISVHMSGGTTEILLTSKQDSHH
                     NVCDTNLGKIAKISIKKDDKSKLYNNFGYNIDIIGGSKDISFGQLIDRVGIKLGYKFP
                     SGKYLDENALNCNLKIESGLKTSVRDGYMNLSGLENQVNKIINDNGDNTNQKEYISKL
                     VLDSVVRNMFKSLVYLCETYNVNEVVFAGGVSASKYILRELSMKLRKKHIEAYFTEPQ
                     YSTDNAVGCAIIGLNNFLGERV"
     gene            26467..27672
                     /gene="xseA"
                     /locus_tag="ACGI5H_001018"
     CDS             26467..27672
                     /gene="xseA"
                     /locus_tag="ACGI5H_001018"
                     /EC_number="3.1.11.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902301.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009318 - exodeoxyribonuclease VII
                     complex [Evidence IEA];
                     GO_function: GO:0008855 - exodeoxyribonuclease VII
                     activity [Evidence IEA];
                     GO_process: GO:0006308 - DNA catabolic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="exodeoxyribonuclease VII large subunit"
                     /protein_id="HFG9696742.1"
                     /translation="MKLRALDISEANSYIKRILINDPILSNLKVKGEISNFKVHSSGN
                     VYLSLKDETSKLNCVIFKSNFNRNLKLDNGVKIIANGYISVYERDGAYQLYINEIEIE
                     GIGNLHIEFNRLKEKLNKEGLFDPKYKIPIPKMPNSIGVITSPTGAVIRDIINVIKRR
                     YPKVNIKLYPVTVQGDKSAEEICEAIRFFNHMKNVDTLIVGRGGGSIEELWSFNDEMV
                     AREVFNSQIPIISAVGHETDFTICDFVSDMRAPTPSAAAEIATPSLDDINYKLGNIKS
                     RMSKSLTNQIELDQYRLETVFNKINNYLDSYTIKDKVIQLDKIYDKIIFGIENNLKLE
                     DEKLVKIGALLHNLSPLATMDRGYSITQKNGKVINSIKGLKIKDSIDIVLKDGNLECM
                     IDKIENKEG"
     gene            27674..27889
                     /gene="xseB"
                     /locus_tag="ACGI5H_001019"
     CDS             27674..27889
                     /gene="xseB"
                     /locus_tag="ACGI5H_001019"
                     /EC_number="3.1.11.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419178.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009318 - exodeoxyribonuclease VII
                     complex [Evidence IEA];
                     GO_function: GO:0008855 - exodeoxyribonuclease VII
                     activity [Evidence IEA];
                     GO_process: GO:0006308 - DNA catabolic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="exodeoxyribonuclease VII small subunit"
                     /protein_id="HFG9696743.1"
                     /translation="MNLTYEEAYKRLESILSELESKNASLDESLSLYEEGISLYKHCN
                     KLLDDAKLKISKFNQLGIEEDFKIEEE"
     gene            27892..28779
                     /locus_tag="ACGI5H_001020"
     CDS             27892..28779
                     /locus_tag="ACGI5H_001020"
                     /EC_number="2.5.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428409.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004659 - prenyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0008299 - isoprenoid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="polyprenyl synthetase family protein"
                     /protein_id="HFG9696744.1"
                     /translation="MEFKQCLKEKASFVEKVLKEYMPKEEGYQKTVIEAMNYSLSAGG
                     KRLRPILTLEACKIVGGNEDEAIPFAIAIEMIHTYSLIHDDLPALDNDDLRRGRPTNH
                     KVYGEAMGILAGDALLNYAFEVMLAGSINKENPEKYLKAINEIAKGAGIYGMIGGQVV
                     DVESENKQIGKEKLDYIHMNKTAAMMVGCMRAGATIGGANSEQMEEITKYAKNIGLSF
                     QIVDDILDIVGDEAKLGKKVGSDIENHKSTYPSLLGLDKSKEIAHNLIDEAKKSIEKL
                     SDDVDFLKGLAEYIIDREY"
     gene            28809..29246
                     /locus_tag="ACGI5H_001021"
     CDS             28809..29246
                     /locus_tag="ACGI5H_001021"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428407.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="divergent PAP2 family protein"
                     /protein_id="HFG9696745.1"
                     /translation="MDFFSEIFNNGALGISLIACFLAQFIKIFTGKEKRIELSRILIS
                     GGMPSSHSSFVTSLATVVGIEKGFNSTDFAIITVLALIIMYDAAGVRRAVGKQATILN
                     QMVADIQHGKHIEQKKLKELIGHTPLEVWFGALLGIVTALILM"
     gene            29280..31145
                     /gene="dxs"
                     /locus_tag="ACGI5H_001022"
     CDS             29280..31145
                     /gene="dxs"
                     /locus_tag="ACGI5H_001022"
                     /EC_number="2.2.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438134.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0008661 - 1-deoxy-D-xylulose-5-phosphate
                     synthase activity [Evidence IEA];
                     GO_process: GO:0008615 - pyridoxine biosynthetic process
                     [Evidence IEA];
                     GO_process: GO:0009228 - thiamine biosynthetic process
                     [Evidence IEA];
                     GO_process: GO:0009240 - isopentenyl diphosphate
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="1-deoxy-D-xylulose-5-phosphate synthase"
                     /protein_id="HFG9696746.1"
                     /translation="MYKYLDKVNSPKDIKNMSIEEMDLLAKDIRKFLVKSVSKTGGHL
                     ASNLGVVELTLALHKVFDSPKDKIVWDVGHQSYVHKIVTGRKDCFVSLRQFNGLSGFP
                     KENESPHDIFDTGHSSTSISIATGIACARDIKKENYSVISVIGDGSITGGMALEALNQ
                     LGYIDTNMIVILNDNEMSIDKNVGGMSKYLSSIIRNSTVEKMTDEVDKILNVTQTGEI
                     LSKTAHRFKDKLMYSFSPQDCSFFDSLGIRYYGPIDGHNTKELIDILRKAKHKKGPVL
                     LHVITKKGKGYRFAEEQPDKYHGVSKFDIKTGVTSAKVKSMSISVGEKLVDMANSNEN
                     IVAITAAMPSGTGLNLFESAYPKRYYDVGIAEQHATGFAAGLAKNGMKPYFAVYSSFL
                     QRAYDQVIHDVCITKKPVTFLIDRAGLVGNDGETHHGMFDLSYLNSIPNIVVMAPKDT
                     REMELMMDLSLKLDCPLAIRYPRGSSYYLDKGEYGEIVLGKYEVLDDGQDTVILCIGS
                     MVKHALEAKEILSREGINPTIVNARFLKPIDEGMLKALLKNHKNVVTIEDNIVTGGFG
                     SRINKFIIDNEYNVNILNIAIPEEFVKHGNIDELYDFVGLSPKSIADKIRKLVIE"
     gene            31278..32090
                     /locus_tag="ACGI5H_001023"
     CDS             31278..32090
                     /locus_tag="ACGI5H_001023"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428401.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TlyA family rRNA
                     (cytidine-2'-O)-methyltransferase"
                     /protein_id="HFG9696747.1"
                     /translation="MKKRIDLLLVEQGYFESRERAKKAIMAGLVFVDNQRCDKAGTEV
                     KEDCSIEVKGNPIPYVSRGGLKLEKAMKNFDLTIDGKVCMDIGASTGGFTDCMLKNGA
                     IKVFSIDVGYGQLAWKLRQDDRVVCMERTNIRNVTIEDTKQFADFASIDVSFISLKLV
                     LPKAKELVRHDGEVVALIKPQFEAGREKVGKKGVVREKSTHIEVIKMISDFSVENGFE
                     ILGLDFSPIKGPEGNIEYLIHLRNGNEGYEFDGETYNNKIVEVVEASHNLDK"
     gene            32110..33789
                     /gene="recN"
                     /locus_tag="ACGI5H_001024"
     CDS             32110..33789
                     /gene="recN"
                     /locus_tag="ACGI5H_001024"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888953.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RecN"
                     /protein_id="HFG9696748.1"
                     /translation="MILELYMKNCALVEELRLNIDKNLNILTGETGSGKSIIIDALGL
                     CLGDKYDRSFLRKGTDKGLVEAVFFSDNRYLKKILEENDISMEDDNLLVITRLIYSDG
                     KSTARVNGRTVKVSLLKEIASTLIDIHGQHQNQALFNKDTHLKFLDLFGENELEEFKI
                     AYKNVYHKYSEVKKALNCLTENKDEMQIQREIDLLRFQINEIEAANLNKNEYEDLLKQ
                     REVYRNSEKIYNNLNSSYSKLHNGEYNVIDLIGLASKELNDISKYDSVLSEYSDTVER
                     IMYELQDISGEIRNYKDNIDFEPYELEQIELRIDEINNLRRKYGDSIDDIFEYYGKIK
                     DRLDEILNRDERVEQLRSKLMNIEEDLKIKASKLTKARIEVATTLEKILLDELKSLNM
                     KNVMFKVNFEKGPFTLDGVDDIEFMISFNLGEDIKPIYKVASGGEMSRFMLAFKTILA
                     DIDDIDTLVFDEIDTGISGIAAQIVGEKLSDIAKKKQIICITHLPQIAANADTHYCIE
                     KDTSNNRTFTNVSKLNESQRKNEIARLIAGNNITEKTIEHASEIIELAKKC"
     gene            34003..34869
                     /locus_tag="ACGI5H_001025"
     CDS             34003..34869
                     /locus_tag="ACGI5H_001025"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861142.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9696749.1"
                     /translation="MNKKDTMHLIFTIVIFILLWYIVVAVSEINKNIESCSNKLDYLS
                     QEIMSTKSDISNTINEEMSKSYITKSIDLKVKKIEKKECVIDVDVQLSKLGKNGKVFF
                     MYKEDSDKWNETEMTKHGELSYACEIKINTGSEYDYKVVTSGAISESSDVQKLTKSDY
                     MPEQPIFNSGIRDNREYFIEIVENSNLFNHESEKSKNKVYDNIRLEKVDIIVNEGKKD
                     TIYKAKLAEGLDDGKTNNSNRNQVNYEVSFPKRDIDDIIYIKAKLTYNNGVEYTKDIT
                     EDITMGLQDLEK"
     gene            complement(34962..35441)
                     /locus_tag="ACGI5H_001026"
     CDS             complement(34962..35441)
                     /locus_tag="ACGI5H_001026"
                     /EC_number="2.3.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905362.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:0016746 - acyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HFG9696750.1"
                     /translation="MAQNITLQFVEEKDLENLENVKLLFTEYSNSLNIDLCFQDFNNE
                     LKTLPGKYKKPSGSLILAFVDENLAGCVALKKLEGKICELKRLYVRNQFRGLKIGKIL
                     LEEIIEEAKKFGYTHMRLDTLPSMKSAQGLYEKFGFYDIEPYTYNPIEGARYMELKL"
     gene            complement(35514..35954)
                     /locus_tag="ACGI5H_001027"
     CDS             complement(35514..35954)
                     /locus_tag="ACGI5H_001027"
                     /EC_number="2.3.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861143.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HFG9696751.1"
                     /translation="MKLNVRIADINNWHDLVSLSVDKSQLDYIESNALSIAESKFITA
                     WVPVGIYDENSLIGFAMYGRLEDDRVWLDRFMIDSKYQGKGYGKASLDFLVNHLKNEY
                     NCDELYLSIFEDNKMAIKLYKDFGFEFNGELDYGGEKVMVLKSN"
     gene            36115..37173
                     /locus_tag="ACGI5H_001028"
     CDS             36115..37173
                     /locus_tag="ACGI5H_001028"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428391.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SpoIVB peptidase S55 domain-containing protein"
                     /protein_id="HFG9696752.1"
                     /translation="MNKINKNFKNIWIILGAVSIFTMVIIFNKNCNVNKETQIEAFTI
                     KNHDKKFVYPMGNIIGVKANTDGVLVLGYEEEDVDYIGGIQIGDNIVKIDNKRIKNSQ
                     DVSEILNKIKKSKVEVTFERKNKYKTEVIETKKENGKYKLGLWVRDKISGIGTMTFYD
                     PSMEKFKAIGHAIKDSDTNELLKIKQGYIYKPEQLKIVKASNEKVGKIKGDFNDSNLM
                     GNFSNNSELGISGNITENHNKEFNVANKEKQLIEVGRPQDVKIGDAVILFEDKNKNIT
                     SYDIKIESIVYDKGNYRDMVIKVVDDKLLEYTGGIVQGMSGAPIIQNNKIIGAITHVF
                     RDNPKKGYGIFIDEMIKL"
     gene            37315..38139
                     /gene="spo0A"
                     /locus_tag="ACGI5H_001029"
     CDS             37315..38139
                     /gene="spo0A"
                     /locus_tag="ACGI5H_001029"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419197.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0005509 - calcium ion binding [Evidence
                     IEA];
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA];
                     GO_process: GO:0042173 - regulation of sporulation
                     resulting in formation of a cellular spore [Evidence IEA];
                     GO_process: GO:0043937 - regulation of sporulation
                     [Evidence IEA];
                     GO_process: GO:0051606 - detection of stimulus [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sporulation transcription factor Spo0A"
                     /protein_id="HFG9696753.1"
                     /translation="MGGFLVEKIKIVLADDNKDFCQVLKEYLSNEDDIDILGIAKDGI
                     EALDLVKKTQPDLLILDVIMPHLDGLGVIEKLNTMDIPKMPKIIVLSAVGQDKITQSA
                     INLGADYYIVKPFDFVVFINRIRELVSNRVTQVEPKPRPVQETQMTRSDFVKNVGNIE
                     TEITNIIHEIGVPAHIKGYLYLREAIKMVIDNVELLGAVTKELYPSIAKKFNTTPSRV
                     ERAIRHAIEVAWSRGKVDTINQLFGYTVHNTKGKPTNSEFIAMIADKLRLEHSMVK"
     gene            38552..39673
                     /gene="steA"
                     /locus_tag="ACGI5H_001030"
     CDS             38552..39673
                     /gene="steA"
                     /locus_tag="ACGI5H_001030"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428389.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative cytokinetic ring protein SteA"
                     /protein_id="HFG9696754.1"
                     /translation="MRVEAPIKVDRKTKKLAKRVESGEIAVINHIDIDEVAANSLVEA
                     KIKLVINAAPSISGRYPNKGPGILTENNILIIDNVGEELFEELKEGETIEVVDGKIYR
                     KGKFLGAGEVLDKYEVSHQIKAAYENLAVELDRFIDNTIDYAKKEKGFILGEVEIPKV
                     KTNYANKHVLIVVRGQDYKEDLSTMLSYIEEVKPVLVGVDGGADALIEFGYTPDVIVG
                     DMDSVSDEALKKASEIVVHAYTDGRAPGLKRVEELGLDAVVFPAPGTSEDIAMLIAYE
                     YKAELIVAVGTHSNMIDFLEKGRKGMASTFLVRLKIGSKLIDAKGVNLLYRSKLKIKY
                     IWALIATALFPVLVVASLSPGVQQFIQLMQLKFRVLLQM"
     gene            39691..40566
                     /locus_tag="ACGI5H_001031"
     CDS             39691..40566
                     /locus_tag="ACGI5H_001031"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_process: GO:0055070 - copper ion homeostasis [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="copper transporter"
                     /protein_id="HFG9696755.1"
                     /translation="MHINMKYYIVTIGAIFIALGIGMLVGFNLNNNQQLSEQQANIIN
                     DLDDKFNILKEKNDKLDSDLASVNRDYEEAVNFINKNVDKILAGSLNGKSIGIISANE
                     NDDYTKNIEDIINKSNGSIAFNIILKENITNPEKLKEMSTKLGTDVKNANDAVNYIID
                     TLKKEDASDILTYLQELDVIKFNFIGDTYLKYDSVVIAGGNDAKDSTKQFEKIEKFVV
                     SKLKSENKYLVEVQNTGVKTSYVELYSKNKVATIDNIDEGIGSISLAILLQQGNIVGN
                     FGRLDTATSLLPSIK"
     gene            40590..41282
                     /locus_tag="ACGI5H_001032"
     CDS             40590..41282
                     /locus_tag="ACGI5H_001032"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428385.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HFG9696756.1"
                     /translation="MDSYISIIIPAYNEESRIKYTLESILDIKQINEIIVVDDGSIDN
                     TAKVVSELENEKIKFFKLDKNRGKGYALNYGIKLAMKNADIIGFLDGDLGSSAKEVEK
                     LIVPILNGEADVTIAKFPPAKRKGGLGFVKGLAKNSVFEMTGVELDATLSGQRIFKRE
                     VLEKFDEIPFGYGVEVGMTIDILKYGFKIKEVLVNMTHNETGRNLKGFIHRGKQYYHI
                     KKVLGQKKKEWR"
     gene            41290..42114
                     /locus_tag="ACGI5H_001033"
     CDS             41290..42114
                     /locus_tag="ACGI5H_001033"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428383.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyl transferase"
                     /protein_id="HFG9696757.1"
                     /translation="MKDYILYTILLLTGLFGTYAVIPLFKNLLINGNVLRPNYKKDMI
                     PVSMGIVFLPMIVINGIILAFFTTEFKNLAYIFMFMFGMISMFFAGILDDVIGNRDVS
                     GLKGHFKSLFKGSLTTGGFKALFGGFVGLIVSVAISKDIIDIIVNTLIIALSTNLMNL
                     LDLRPGRAIKAYLFIMVIVFLTLTGFVQVLPLLIVPNVLAYFNYDLKARAMMGDTGSN
                     VLGISIGMLISFGYPFNIRLGWLIFVVIMHIFTEKYSLTKIIEKNKLLNFIDKLGR"
     gene            42119..43186
                     /locus_tag="ACGI5H_001034"
     CDS             42119..43186
                     /locus_tag="ACGI5H_001034"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896132.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3866 family protein"
                     /protein_id="HFG9696758.1"
                     /translation="MISKRVGIVESIVSQTETLDDIRVNINGEIQKAYNYPKISGTIN
                     IGDEVVLNTTAVELSLGTGGYHFVITNLNNIESTLTEGGHIMKLRYTPLQIKVDSVEE
                     QESIYHDKFANFKGLEGLSVVVGTLHSMLTPFAASFKRNNPNKKLVYIMTDGASLPIY
                     LSKNVDTLKEKKLIDSTITIGNAFGGDYECINIYTALITAKEILKADAVFVSMGPGIA
                     GTGTKYGFTGIEQGSILDAVKKLEGRAIAIPRISFADKRERHQGISHHSMTVFKEIVN
                     VNVDIPITIYDDEKLNFIKEQINLNGLDKKHNIIYIDNNKTKEDLDYFNLKVKSMGRN
                     YEQDEAFFKAASTAAYYLMEV"
     gene            43188..43724
                     /locus_tag="ACGI5H_001035"
     CDS             43188..43724
                     /locus_tag="ACGI5H_001035"
                     /EC_number="3.6.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419216.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
                     /protein_id="HFG9696759.1"
                     /translation="MVLEEKTISSDRVYTGKVITLKVDTVEIPGQGYQKRELVEVGGA
                     VGIVAITDDNKVVLVKQFRKPIEKPIFEIPAGKLEKNESPKECAERELKEETGYSAKN
                     IKLIHKFFTSAGFSNEIMFVYLATGLTPGENNLDADEFLDVYEIELEEAYNMVLKNDV
                     EDAKTSIGLLLVKDMFKN"
     gene            43792..44397
                     /locus_tag="ACGI5H_001036"
     CDS             43792..44397
                     /locus_tag="ACGI5H_001036"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888973.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="stage II sporulation protein M"
                     /protein_id="HFG9696760.1"
                     /translation="MRRTYRKNDFRELNRQIIIIGLLFMMSIVVGSYINKILPGSSNN
                     ILNNINPAVEYYNLNISIKDTVIQNLKSDAIFMGSIALLSLFVVTIPAVLVAFVLKGM
                     SIGYTINSCILALKFKSIKMILIILFKNLIIIPCAIILALISLSYFKEMVYEFKKKSR
                     KNMQFLIKRYILNIIIIIALSLGLQLILNTASIGIIKFLAK"
     gene            44409..45323
                     /locus_tag="ACGI5H_001037"
     CDS             44409..45323
                     /locus_tag="ACGI5H_001037"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896134.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA];
                     GO_process: GO:0015074 - DNA integration [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HFG9696761.1"
                     /translation="MDIIEGYIDYIKDKKKLSENTVASYFMDIKKYMEYINQKSIKLV
                     DIVENDIISYLIKLEKDNVSIATIARMISSIKSFHDYLFLNHICTNNPAKDIKKPKIK
                     KENINILTEEEIERLLNFPKLTTPKLIRDKAIFEVLYGTGIKVSELVEMNIEDIDLDI
                     DYIYCNSCCKNQRVIPLCDITKLYLEKYLKEARPKMAAEGEKSLFVSSLGQRFTRQGL
                     WKVIKKYSNLANIDKNINPTMLRHSFAIHLLNEGANIAVVSKILGNVNLSSLQVYLNH
                     IDKNVRREIKEKHPRNDVDVELQKAEAK"
     gene            45365..46537
                     /locus_tag="ACGI5H_001038"
     CDS             45365..46537
                     /locus_tag="ACGI5H_001038"
                     /EC_number="5.4.2.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428374.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000287 - magnesium ion binding [Evidence
                     IEA];
                     GO_function: GO:0008973 - phosphopentomutase activity
                     [Evidence IEA];
                     GO_process: GO:0009117 - nucleotide metabolic process
                     [Evidence IEA];
                     GO_process: GO:0043094 - cellular metabolic compound
                     salvage [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphopentomutase"
                     /protein_id="HFG9696762.1"
                     /translation="MSRVIWIVIDSVGIGALPDAEKFGDSKDVSTLGNIFKEYPDIQI
                     PNMRNLGIGNIEGIDFFESIKEPIGCFGKCKEMSQGKDTTTGHWEMTGIIVDKPFKTF
                     EHGFSKEIIEEFEKKTGRKVVGNKPASGTVIIDEYGEHQIKTGDVIVYTSADSVFQIA
                     ANEEVIPLEELYNMCKIAREIMMGDNAVARVIARPFIGKKKGEFVRTSNRRDYSLDPF
                     EPTVLDNIKESGLDVLAVGKIEDIFNGKGITDAIHTKSNMDGVDETLNYMKQDNKGLI
                     YSNLVDFDSKYGHRRDPEGYKKALEEFDSRLPEIMANMREDDILIINADHGNDPTYKG
                     TDHTREYIPVMIYGNKIKKGFNLGVKDTFADIGATVADILNVKLPKHGSSFKEDLF"
     gene            46584..47396
                     /locus_tag="ACGI5H_001039"
     CDS             46584..47396
                     /locus_tag="ACGI5H_001039"
                     /EC_number="2.4.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888977.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004731 - purine-nucleoside phosphorylase
                     activity [Evidence IEA];
                     GO_process: GO:0009116 - nucleoside metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="purine-nucleoside phosphorylase"
                     /protein_id="HFG9696763.1"
                     /translation="MFEKIAQSSKFINSKSNIKPKIGLILGSGLGDLANDIEDPVTIK
                     YSEIPNFPVSTVAGHAGQLVIGKLEGKEVIAMQGRFHYYEGYSQKEATFPVRVMKELG
                     VEILIVTNAAGGVNKEFKAGDLMLIRDHINFSGSNPLVGKNDDRFGARFPDMSDAYSS
                     KYVDVVKNCAKECNIDVKEGVYMFFSGPNYETPAEVRMAQILGADAVGMSTVPEVIVA
                     SHSNIGVIGISCITNMAAGILNQPLSHEEVIETTQKVKSEFMNLVKTTVKNL"
     gene            47600..48925
                     /locus_tag="ACGI5H_001040"
     CDS             47600..48925
                     /locus_tag="ACGI5H_001040"
                     /EC_number="2.4.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892935.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016154 - pyrimidine-nucleoside
                     phosphorylase activity [Evidence IEA];
                     GO_process: GO:0006213 - pyrimidine nucleoside metabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pyrimidine-nucleoside phosphorylase"
                     /protein_id="HFG9696764.1"
                     /translation="MRMYDIIKKKRDNLELSKKEINYFIENYSKGDIPDYQASALLMS
                     IYLNKMNKQETVHLTEAMMNSGDMINLSEIDGIKVDKHSTGGVGDKTTIALIPLVASC
                     GAPVAKMSGRGLGHTGGTIDKLESIPGFSTEMEISKFIDSVNKSKIAVCGQSAKVAIA
                     DKKIYALRDVTATVDNISLISSSVMSKKLASGADAIVLDVKTGDGAFMKTLEESFELA
                     KSMVDIGTGMNRDTIGIVTDMDEPLGFAVGNSLEVIEAIETLKGNGPKDLVELCEVLG
                     AYMLVLSKVAHDFEDGVEKIRESIKSGTAIQKLKEFIENQGGNKDVVDDYSLFKKSKY
                     KYPVKSTKSGYISKIKAEDVGVSAMILGAGRETKDDILDLSAGIILEKKVGDYVNEGE
                     VLAYMYYNDEQKLSLAKGRFIDSYSIVDSKIEKNKLIYGIVTKEEIKKF"
     gene            49138..50217
                     /gene="mltG"
                     /locus_tag="ACGI5H_001041"
     CDS             49138..50217
                     /gene="mltG"
                     /locus_tag="ACGI5H_001041"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419238.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008932 - lytic endotransglycosylase
                     activity [Evidence IEA];
                     GO_process: GO:0009252 - peptidoglycan biosynthetic
                     process [Evidence IEA];
                     GO_process: GO:0071555 - cell wall organization [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="endolytic transglycosylase MltG"
                     /protein_id="HFG9696765.1"
                     /translation="MNFKENRLKIAVLIIVILIILAGIFVFIQIGPYDKNNKKDVIID
                     VPSGASVGKISDILYENKLIKNELLFKLLVKVSNKAPSIKSGTYLLNQSYSNNDIISL
                     LVSGKIYQDGIKVTIPEGATSKEIIAMLVSKNLGDKATFENLIKKPQEFYDKFSYLKE
                     DGITSLEGFLYPETYYFNSKKQSEEDILSEMLKVFDSKYTDKFKKKQKELNMTLQEVM
                     EMASIIEKEAVLDKDRPIIASVFYNRLKVGMPLQSDATIQYIFEERKKIVTYDDLKID
                     SPYNSYKNKGLPPTPISNPGIKSIEAALYPEKTDYLYFVAKIDGGNNYSTNYQDHLKY
                     VKEYKEARDKQSKDTKATNKENTKK"
     gene            50389..51063
                     /locus_tag="ACGI5H_001042"
     CDS             50389..51063
                     /locus_tag="ACGI5H_001042"
                     /EC_number="2.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419240.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008757 - S-adenosylmethionine-dependent
                     methyltransferase activity [Evidence IEA];
                     GO_function: GO:1904047 - S-adenosyl-L-methionine binding
                     [Evidence IEA];
                     GO_process: GO:0032259 - methylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="O-methyltransferase"
                     /protein_id="HFG9696766.1"
                     /translation="MSNIVNDLVEDYIRVTLKEKEGFLKDLEIYAEENSVPIIHKEVS
                     DLLKVLLKVQKPKRILEVGCAIGYSSIFFATIIGKDADIITVERNEKMIEKAKENIKL
                     AGFDNNITILEGDAEEKLSQVQGEFDLIFIDAAKGQYKLFFDLVIDKLKDGGLLVSDN
                     ILYKGMVAHDDFVVRRKKTIVKRMRKYLDYICNCDYLSTSLVPIGDGVALSYKESKRG
                     DVDGIK"
     gene            51050..52297
                     /locus_tag="ACGI5H_001043"
     CDS             51050..52297
                     /locus_tag="ACGI5H_001043"
                     /EC_number="3.4.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438167.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:1901576 - obsolete organic substance
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="U32 family peptidase"
                     /protein_id="HFG9696767.1"
                     /translation="MELNKVELLAPAGDLERLKIAITYGADAVYIGGEIFGMRSAAKN
                     FSKEDMAEGVAFAHERGKKVFVTVNIIPHNEDFLQLEDYLLELEEIGIDAVIIADPGV
                     LSVIKKVIPNMEIHLSTQANTTNYLSANFWYEHGIKRVVVARELSFDEIYEIRAKTPL
                     DMDIEAFMHGAMCISYSGRCLISNYMTGRDANKGSCAQSCRWQYHLVEEKRPGEYFPI
                     YEDERGTFFFNSKDLCMIEYIPELIKSGITSLKIEGRMKTAYYVATVVRAYRMAIDEF
                     YRDPENWKFNPMWMEELKKGSHRHFTSGFYLNKPTTEDQNYQSASYVRNYDFIGIVRE
                     TEDEDGLIVVEQRNKMCVGDEIEVMGPYKETMFTKIEEMYNEEGEAIESAPHPRQIVK
                     LKLSVKVGKDYMLRKVIEEKVEE"
     gene            52369..54039
                     /locus_tag="ACGI5H_001044"
     CDS             52369..54039
                     /locus_tag="ACGI5H_001044"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896136.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0008658 - penicillin binding [Evidence
                     IEA];
                     GO_process: GO:0009252 - peptidoglycan biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="peptidoglycan D,D-transpeptidase FtsI family
                     protein"
                     /protein_id="HFG9696768.1"
                     /translation="MSKKKTPFLKKVGKRSWCIFTIILIIYSVLIYRLVDIQVLKGDK
                     YKQSVESQSVEKVELNSGRGIIYDRNNKKLTDTSKSQVLIVEKEKLNNNYKILELIKK
                     ATKMNDLDIYKAVQEQLTRPIIQIQTKNIDIDKSMKKELEKNGIMVEEKTMRYAKDGL
                     LSHTIGYIKEDDKSGQSGIEKSMDSVLRNSNEKYISAFKAGDAGNEKSLNILKGSVKT
                     VDNKDKDRHLKTTIDYNIQKKLEQILNKEENPTAAIISEASTGEILAMCSRPNFDQND
                     ISKSLKGKNGEFENRVIKATYPPGSVFKMVVLFSALENGVIDENYTYNCTGKTKVGNT
                     NEILRCNKRDGHGFQNLRQAFSNSCNPAFLDIAMKLGKEKILKSAEKLHLFEKVDIGL
                     DEEKIREAPKNISIRNLAIGQENIEFTPLQINQMTQIIANNGTFKPLYLYKSLVDNNM
                     NTIKTYKSSKKEELISPYVCTQVKEYMKSVSRTGTAKDLKDIEGGCGVKTGTAQSSLN
                     KKAIDHGWITGFYPEERPKYVITVLVEGTQKGNKSATPIFKEICESIK"
     gene            complement(54136..54420)
                     /locus_tag="ACGI5H_001045"
     CDS             complement(54136..54420)
                     /locus_tag="ACGI5H_001045"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012063608.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_function: GO:0016987 - sigma factor activity [Evidence
                     IEA];
                     GO_process: GO:0006352 - DNA-templated transcription
                     initiation [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-70 family RNA polymerase sigma factor"
                     /protein_id="HFG9696769.1"
                     /translation="MCNEISLLDILGTEANYVLDEVELKVQVGKLYEQLNKILTPRER
                     EIVQLRYGLTPYGYKTQREIAQKLDISRSYVSRIEKKALKKLEKELVQES"
     gene            complement(54446..55960)
                     /locus_tag="ACGI5H_001046"
     CDS             complement(54446..55960)
                     /locus_tag="ACGI5H_001046"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905372.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000150 - DNA strand exchange activity
                     [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HFG9696770.1"
                     /translation="MSVAIYLRKSRADEEAEKQGEFETLSRHKSTLLKLAKEQNLDVI
                     EIKEELVSGESIIHRPKMLELLKEVEENKYDAVLVMDLDRLGRGDMKDQGIILETFKE
                     SKTKIITPRKTYDLTDEFDEEYSEFEAFMARKELKLISRRMQRGRIKSVEEGNFIGTS
                     APFGYDAVTTGRKERILVPNKDADVVRTIFDLYINEDMGCSKISKYLNNLGIKTATGA
                     NWYNSAITNIIKNKVYCGYIQWQKKDYKKSKNPNKIKTVKLRPKDEWIEAKGKHEPLI
                     SEITWKKAQNILKKNGHVSYGNQIKNPLAGIVICKNCGRPLVYRPYADHDYIICYHPG
                     CNKSSRFEFIEAAILKSLEDTVKKYQLKASDLDLDKNNKDSNIEFQKRVLKGLETELK
                     ELGKQKNKLYDLLERGIYDEDTFIERSNNISSRTEEIKDSIKTVKNRLSTVKKDNAKI
                     IEDIKTVLSLYHDSDSLGKNKLLKSVIDKAVYYKSKEQKLDSFELMVHLKLHED"
     gene            56192..56344
                     /locus_tag="ACGI5H_001047"
     CDS             56192..56344
                     /locus_tag="ACGI5H_001047"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896140.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9696771.1"
                     /translation="MDNFLFNVLASLTASVVVYLISKLFKKAKSHSRTKSDLRVEFKF
                     IFKSKK"
     repeat_region   56633..56797
                     /inference="COORDINATES: alignment:crt:1.2"
                     /inference="COORDINATES: alignment:pilercr:v1.02"
                     /rpt_family="CRISPR"
                     /rpt_type=direct
                     /rpt_unit_range=56633..56661
                     /rpt_unit_seq="gttttatattaactaagtggtatgtaaag"
     gene            complement(56968..57183)
                     /locus_tag="ACGI5H_001048"
     CDS             complement(56968..57183)
                     /locus_tag="ACGI5H_001048"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896141.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HFG9696772.1"
                     /translation="MLKDLRILRGLTQKELANRTNYSREYISDLERNKYKNITIPTIV
                     DLSIGLEISPLLLACHFIDEELKKRDK"
BASE COUNT        23162 a         5942 c        10577 g        17992 t
ORIGIN      
        1 taaaaaaaaa gtatatactt ttatattaaa aggtgatata ttatttatga aaatcgttta
       61 atgtatacaa taatatatct ataacaaaat aataaaagat agagttttat ttagacattt
      121 attacaaatc aaaatttatt acatattatt tataaaaaaa tctaaggagg aaataataat
      181 gaaaatatta gtattaaact gtgggagttc ttcattaaaa tatcaattaa tagatatgaa
      241 taatgaagaa gttttatgta taggattggt tgaaagaata ggaatagaag gttctatatt
      301 aaaacatgaa aaagcaggta gagatgataa atacgttgtt gaacaaccaa tgaaggacca
      361 caaagatgca atagcattag ttttagaagc tgttgctcat ccagaatttg gtgcagttaa
      421 agaaatgaaa gaaatagatg cagtaggaca tagggttgta catgctggag aaaaatttgc
      481 aacttcagta gtaataactc cagaagtaga agaagcttta aaagaatgta tagatttagc
      541 tccacttcat aatccagcaa acataatggg aatagatgct tgtaaagcta tacttccaga
      601 tgtaccaatg gtaggtgtat ttgatactgc tttccatcaa acaatgccta aatcttcata
      661 cttatatggt ttacctcatg agctatatac taaatatggg gtaagaagat atggattcca
      721 cggaacttct cataattatg tatctcaaag agcagcagag atattaggaa aagatataaa
      781 agatttaaaa atagtaactt gtcacttagg aaatggtgct tctatagctg ctgttgatgg
      841 tggaaaatgt gtagatacat ctatgggatt cactccatta gaaggattaa taatgggaac
      901 tagatgtgga gatatagacc cagctatatt accattctta atgagaaaag aaggtttaga
      961 tgctgatgga ttggataaat taatgaataa agaatctgga gtatatggaa tgactggaat
     1021 ttctagtgac ttcagagata tagaagatgc agctaaaaat ggagacgaaa gagctcaagc
     1081 tacattagaa gcgtatgtta aaaaagtaca aaaatatata ggcgcttatg ctgctgaaat
     1141 gaatggattg gatgttgtag tatttactgc aggcgttggt gaaaatggaa aggctataag
     1201 agcagatatt gcttctaaca tggagttttt aggaatgaaa ttagataaag aagctaatga
     1261 tgttagagga aaagaaacag taatatctac tgctgattct aaagtaaaaa tgcttttaat
     1321 accaactaat gaagaattaa tgatagctag agatacatta agattggtaa aataattaaa
     1381 ttaaacctat gcctatcaag taaaaatact tgacaaacaa atgctagatt tgtataataa
     1441 atttggtgat atgttgaggt gaacttaatg aaagttagca tagaaaaaat aaatagaaaa
     1501 gaaactgaca aaatagactt gaatttttgt gaaaaaattg atactattag ttattgtgat
     1561 gagatttaca aattagtatc acctgtaaat ttaaaaggga aagtgtcaaa gactaataaa
     1621 ggtttgtatc tagatataga tgtcaatttt acaattgttg acaattgttc aagatgtctt
     1681 aaagaagtag aaataccact agagtattct atacaaggtt ttttagtaaa agaagaagat
     1741 tatgatgaag atgagtttga ggaatttgat ccttttatat tcgatggtga agaaatcgac
     1801 cttattgata taatagaaca gacattagat tttaatgtac ctcataaagt tctttgtagt
     1861 gaaaactgta aaggtctttg tcaagtatgc ggggcaaact taaatgaaga agagtgttct
     1921 tgcagtgaaa ttacaaacga tgaggaatac atagatcctc gttttgctaa attaaaagat
     1981 ttatttaatt aaattttgac taaggaggtg gcgtaaatgg cagtaccaaa gcgtaaaacg
     2041 tctaaatcaa acacaaaaat gagaagagca gctaactcaa agatggaagc aacaggattt
     2101 gtaagttgcc cacaatgtca tgagccaaaa ttaccacata gagtgtgtcc agactgtgga
     2161 tattataaag gtaaagaagt tgtgtctaag taatagcttc taaaaagcat gtagagtata
     2221 ctctacatgt tttttttgta catataaaaa aataagataa tttactagag aaaataagtg
     2281 gattttatgc atattaaaaa atagaaaaat aataatataa gtattgaaaa tttttgtgtg
     2341 ttactatata ctactattag tagctggtac taattacagc tataaaattt ggagggaaca
     2401 tgaaaaagaa aagtaaagcc caaagacaaa aagagcttat agatatgcta aagacagatc
     2461 ctttttatac tgatgaagaa ttatcaagtc tgtttgatgt aagtatacag accataagat
     2521 tagatagaat gagtctaaac ataccagagc taagagaaag agtcaaatca atagcagaaa
     2581 ctcagagttc aaaagtaaag actttaggag taaaggaaat tacaggagaa atcattgatt
     2641 tatctgtagg gcgattaggt atatctatgt tagaagttac acaggacatg atttactcta
     2701 agactaatac tttaaaagat acgtatattt tttctctagc agattcattg gcaatggcta
     2761 taatagatgc acctaaggtt attatgagag ttgcaaatgt aaaaagtttt aagttgatag
     2821 aacaacaaga taggcttata gcaaaagcag aagtgtatag aaatatagat aaaaagcatt
     2881 atgtaaaagt tgttatcaac aataaagccc aagagcaaat atttagagga aagtttatct
     2941 ttgaagaatt agattaggag ggaaattatg aaaatagtaa ttgatggaat gggtggagat
     3001 aatgcaccta aatctaatgt agaaggcgca gtaaatgcta taaaagaata tcaggttgat
     3061 ttaataatca caggagataa agatttactt gaaaaggaat tttcaaatta tgaatttgat
     3121 agaaataaat tagagatagt tcatactact gagattatag aaaacgaaga taaaccagta
     3181 aaggctataa gaagtaaaaa agattcatct atggtagtag cattaaatct tgtaaaagaa
     3241 ggaaaggcag atgctataat atcagctgga aatacaggag ccttacttgc tggtggatta
     3301 tttgttgttg gtagaataaa aggaatcgat agaccttgct tatgttcagc aataccaaat
     3361 gtaaagcgag gaatgacact tatagcagac tgtggcgcaa atgcagattg taaacctaag
     3421 aatctagttg aatttgcagc tatgagtaat atttattcaa gaaaagtttt aggtcttgaa
     3481 aatcctaagg tagcattagc aaatgttgga ctagaagaag gcaaaggcaa tgatttagtc
     3541 aaaaggtcat atgaagaaat taaaaaatta gatttaaatt ttatagggaa tgtagaagct
     3601 agagaagtta taaatgcata cacagatata atcatatgtg atggatttac aggtaatata
     3661 ttacttaaat ctgctgaagg tgtagcactt tcagttatga gtcttataaa ggaaactttt
     3721 atggccagta caaaaagtaa aataggagca ttacttataa aggatgattt aagaaaatta
     3781 aaaagtttta tagattattc tgagtatggg ggagctccac ttttaggtct aaatggagga
     3841 gttataaaag ctcatggtag ttctgatgct aaagctataa aaaatgctat aaatcaagga
     3901 ataaaatttt caaagggaaa agtcgttgaa gatattaacc aatttataag caaatacaat
     3961 gaagaaaata aaaataacga agatgaataa actcgttttg gaggtttaat atataatgaa
     4021 tacaaaggct ggaatattag gagtaggaag ttatctacct gagcaatcat atgataattt
     4081 tcacttcgaa aaaataatgg atacatcaga tgagtggata agtactagaa ctggtattaa
     4141 ggaaagaaga tttgccaaag agtctgaagc aacttctgac ttagcatcta aagctgcctt
     4201 aaaagctata gaatgtgcaa agttaaacgt agaggatata gagctgatta tattagctac
     4261 aattactcct gatatgtctt tgccttcaac tgcatgtata gtacaagatg caataggagc
     4321 agtaaatgct actgcatttg atatatcagc agcttgttct ggatttgtat atggagtaac
     4381 tattgcaaag caatttgtgg aaacaggttg ctataaaaat gtgcttgtaa taggagcaga
     4441 aacttgttct aagtttttaa attatgatga tagaacaaca gcagtattgt ttggagatgg
     4501 agctggagca gctgttattg gccctgtaaa tgagggtgga atactgtcta cacatatggg
     4561 ctctgatggt aaaggaaaag attgtttaaa agtacctgct ggaggttcaa gacttaaggc
     4621 aagtaaagag actgtagaag ctaatctaca tacaatagaa atggcaggta gtgatgtgtt
     4681 taaatttgca gttagaaaga tggcagaaac ttctttaaga gctcttgaaa aagcaaatct
     4741 aaatacaact gatatagact acttagtgcc acatcaagct aatataagaa tcatacaagc
     4801 ttcttctaag agattagagc ttgatatgaa aaaagtttat gtaaatatag acaaatatgg
     4861 aaatatgtct gctgcatcta taccagtagc attagatgaa gcttatagag aaggtaaaat
     4921 taaaaagggt gataatgtag ttttagttgg ctttggtgga ggtctaactt ggggggcttc
     4981 agttgtcaag tggactttat agtataaaat atctaaaatg atttaattaa caaaattaaa
     5041 cttatacaca aaataaagtt gattaataat aaaaagttta cttttatgat ttcaagtgaa
     5101 ggagaattgt atgaataaaa tttgcaaaat attaaatata aaatacccag ttatccaagg
     5161 gggaatggca tgggtagcta ctgcatcatt agcaagtgct gtatctaatg caggaggact
     5221 tggcataata gcagcaggaa atgcaccaaa agaagctata aagaaagaaa ttgttgagtg
     5281 taaaaaatta acagataagc cttttggagt aaatgtaatg cttatgtcgc catttgttga
     5341 tgatataatt gatttgatta tagaagaaaa agttcaagtt attactactg gtgctggaaa
     5401 tcctgcaaag tatatggata gattaaagga agctggaaca aaggttattc ctgtagtacc
     5461 tacaatagct ttggcacaaa gaatggaaaa gctaggagct acagcagtaa tagcagaagg
     5521 tactgaaggt ggaggacata taggagaact tactactatg gtcttagttc cacaagttgc
     5581 tgatgctgta aacatacctg taatagctgc tggaggaatt gtagatggta gaggaattgc
     5641 agcatcattt gcattaggtg ccagtgcagt tcaagtagga actagattta tttgcagtga
     5701 agagtgttct gtccattcaa actataaaaa cttagtacta aaagcaaaag atagagatgc
     5761 aattgtaaca ggaagaagta ctggtcatcc agtaagaaca ttaaaaaata aactatcaaa
     5821 agaattttta aagatggaac aaaatggagc tactcctgaa gaactggata aaaaaggtac
     5881 aggagcttta agatttgcaa cagtagatgg agacatagaa aaaggttcat ttatggcagg
     5941 tcaaagtgct gctatggtaa aagaaataac accttgtaag gaaattatag aggctatggt
     6001 aaatcaagca agagagatta tgccagcaat agaactgtaa atcaggagga gcaagatggg
     6061 aaaagttgca ctagtattcc ctggtcaagg agctcaatat gtaggtatgg ccaaggattt
     6121 atatgaaaat aatgctgttg ctaaaagtgt aatagatgag gctagtgatg ccttaaatat
     6181 ggatttaaaa aaccttatgt ttaatggaaa tgaagaagaa ctttctaaaa ctgaaaacac
     6241 tcaacctgct atggttacac atagtgtagc agtattaaaa gcggtacaag ctcaaataga
     6301 tttaaaatat aatgcatgct taggattatc cttaggagag tatagtgcgt tggttgcagc
     6361 agatgcaatt gactttaaag atgctgtatg tttagttaaa aaaagaggta agtttatgca
     6421 ggaaacagtt ccagcaggtg ttggagctat ggcagcagtt ttaggtttag atagaaatgt
     6481 acttgaaaat gtggttaaag atatacaagg aggtattgta gaagtagcaa attacaattc
     6541 tcctggacaa atagttatat ctggtgaaaa tgaaaagata gaagaagcaa tggtaaaatg
     6601 caaagaagca ggagcaaaaa gggcagttaa attaaatgta agtggacctt ttcactcatc
     6661 aatgttaaaa gaagctggtg taaaattggc cagtgaatta gaaaaagtta acataactaa
     6721 acctaaagtt gatgtggtgg caaatgtaaa tgcagattac tataaaaacg aaggtaaaga
     6781 cctgcttata aaacaagtaa gttcatctgt tctttgggaa gattctatag aaagactttt
     6841 aaatgatgga tatgatactt ttatagaaat gggacctgga aaaactttaa aagcatttat
     6901 taagaaaata gcttccaata aaaaagcaaa tgtcaatatt tataatatag atggtataga
     6961 ttctcttaat gaatttgtac aaaattatag aaatggagag atataatgat aaatcttaca
     7021 ggacaagtag cagttgttac tggtggttct aggggtatag gaaaagaaat agcaaaaaaa
     7081 ctagcatctt ttggagctga tgtagtaatc aattatactt ctaaagaaga tgaagcacta
     7141 aaaactaaaa atgaaataga aagtatgggg gtaaagtgta cctctataaa atgtgatgtg
     7201 tctaaatttg atgaagtgaa tcaaatgata gattctgttg taagcgaatt tggaaaaatt
     7261 gatatattgg ttaataatgc aggcataact aaagatggtc tgcttatgag aatgaaagaa
     7321 gaagattttg atagagttat agatataaac ttaaaaggtg tctttaattg tacaaaagca
     7381 gttactaaac ctatgatgaa aaagaagtat ggaagaataa taaatatgac ttcagtagtt
     7441 ggaattatgg gtaatgcagg gcaaactaat tattgtgcat caaaagcagg tgtaattgga
     7501 tttacaaaag cttctgcaag agagttagca tcaagaaaca taaatataaa tgcagtagca
     7561 cctggattta tagaaacaga tatgactaaa gtactaagtg atgatgtaaa agaatcaaca
     7621 ctagcaaaca taccaaagaa atcttatggt aaaccagaag atgtagccaa tgccgtagca
     7681 tttttagtta gtgacatgtc aagttatata acaggacaag taataaatgt agatggtgga
     7741 atggtaatgc aataataatt taaaaagtag agaaatctat taaaataaaa aattttagga
     7801 ggtacacaat gtttaataaa gttgtagaaa taataataga gcaattagga gtagaagata
     7861 aagaaataac tatggaaaca tcattaatga aggatttaga agcagattca ttagatgcag
     7921 tagaaataat aatggcactt gaagatgaat ttggtataga aataccagat acagaagcag
     7981 aaaacttcaa atctatagga gatatagtta agtatataga agctaataaa tagtcgagct
     8041 ttaaaaaagt ggaggtatcc gatgaataaa agagtagtaa taacaggact tggatgtgtt
     8101 acgccgttgg gaacaggaaa agaagagttc tggagtaata taaaatctgg agtatctggt
     8161 atagataaaa taactaattt tgatgctagc acatatcaaa ctcagatagc aggagaagtt
     8221 aagaattttc atccagaaga atatataagt aaaaaggaat tgaagagatt agataaattt
     8281 gctcaatttg caatagtatc tgctaaatta gcagttgaag atgcaaatct tgatttagat
     8341 aaagttgata gagaacgttt tggtgttata ataggttctg gaataggtgg agttgaagct
     8401 atagaaactc aacataaaat tcttttggaa aaaggaaata aaagagtaag ttcacttttt
     8461 gtacctatga tgataggaaa tatggcagct ggtcaagttt caatattttt aggagcaaaa
     8521 ggacctaaca ctaatgtatg tacagcttgt gcatcaggaa ctcattcaat aggtgatgct
     8581 tttaaggtaa ttcaaagagg tgatgcagac cttatggtag cagggggttc tgaagctgct
     8641 gtaacaggtc ttgcttttgc tggattctgt aacatgaagg ctatgtcaac tagaaatgat
     8701 gaccctaaaa ctgcatcaag accatttgat aaagacagag atggttttgt aatgggagaa
     8761 ggagcaggta ttgttatctt agaagactta gaacatgctt tagcaagagg tgctaaaata
     8821 tatgcagaag tagttggata tggtttaact gctgatgcat accatatgac aactccagct
     8881 gaaaatggag agggagcagc taggtctatg aatatggctt tgaaagatgg aaatgttcca
     8941 ttagaagaag tagattatat aaatgctcat ggaacttcaa cttattacaa tgatttatat
     9001 gaaactatgg ctataaaaac tgtatttgga gaaaaggcat atgacttatg tgtgtcatca
     9061 acaaaatcta tgactggtca cttattagga gcatcaggtg ctatagaggc tgttgtttgt
     9121 gctatgagta tagaagatag ttttgtgcct ccaactataa acatacaaga agttggtgaa
     9181 gatttggatt tagattatgt tccaaatcaa ggtaaagaaa aaaatattag atatgcacta
     9241 tcaaattctt taggatttgg tgggcataat gctacaatag tactaaaaaa atatgtataa
     9301 ataaatatta aatataaaac taaaaaacaa gcacttgttt taactgtata aatttatatt
     9361 agcttaaatt taaagtctcc taaattattt taggagattt ttttattaag atttaagtct
     9421 aggatatgtt gtaaatcatt ttgatatatt gtattattaa ttattaagag gttatttata
     9481 tatgcaagtt ttcattctac aatatacaaa aggaggacta aaattttgaa ttttagacta
     9541 ccaaagaaaa ggttacccaa aaagataatt tttatatgta taatacttat tagtattatt
     9601 ttgtttataa agtatgacca aaatggattg aaagaaagag aaattataaa taagggaaaa
     9661 tatatgtctg aaagccttgt ggcagataag gagtatgatg aagcaaaaaa agtggttaag
     9721 acttcttttg aatctattcc agaaaaaaaa tacaataaag tatataatga agtttgggat
     9781 atgttaaaga ctatttcata tgttccagat ggaacgaaga tagtcattga ttctttagaa
     9841 aagatgagag aatcagatgt gaaattatct gatgaatgta gatttaatat agaaaaaaga
     9901 ttagcatcag tgtatataat ggataataat tattctaagg cagtagattt aactgtaaag
     9961 tctataaagt tggctgagaa attggggaat aattatgaaa aagcaagact agatgttgat
    10021 ttggcgagca tatttttaaa gataggtggc tatgaaacag gagagaaatt aataaaggat
    10081 tcttttaaaa tagatattga tgaaggtgaa aaaaatggaa tggttagatt atatgctatt
    10141 ataaatctag cagaaatata tgtagaagag ggcgaatatg ataaagctat tgaaataagt
    10201 agcaggataa aagattataa aaagtttgta aatacggata attacaatga ttttgatata
    10261 atggcctcta taatgcagtc aaatgcgtat gtgggcaaaa ataatataca aaaggcaaag
    10321 acttttttag aaaaagctga ttatcttata aaatcagata gaacagttta tatattagat
    10381 aaagatatgt actattatat ggcaatggga aacttagaat ataaaagcga aaattataat
    10441 tctgcaatag ataattataa aaaaagttta gagatatcta ctaaaagaaa gttaacccag
    10501 gagaaaataa aaaatttaaa taagatatta aatatatatg aaaaacaagg aaatatagaa
    10561 tctttaaatg agtatcaaaa gatgttaata aatgaatata aagagaacaa aagtataaga
    10621 gattcagaga ctagtttcta tataattgat aaagtatcaa acgaaagtaa gctatttgaa
    10681 aaaactaaaa aagaaataaa atattataaa atattattta cagtaatttt aattgctata
    10741 ttagggtcta cttttttata caaccgattg aagtatttta aagcacaaaa tttacatgat
    10801 ggtcttacaa atgtttataa tagaaaaagt tttgatatta tgtatgaaaa gtacagagag
    10861 aaagatgata attttgcact tgtgatgata gatattgata atttcaagct cataaatgat
    10921 aattatggac ataaatttgg tgacactgtt ataaagggaa taacaaatac catttgtgtt
    10981 atgttagaac aagatgataa agtctttagg tacggaggag aagaattttc tgtattaata
    11041 agaaataaat ctggtgatga agtagcagat ataattgaca gtataagggt tgcaattgca
    11101 aataaaaagt ggaatgatga tgtgactgtg actataagtg caggtgtagc tcatgtttca
    11161 gatagcaaag atgtactaga agaagctgat aaaaatttat ataaagcaaa acaacttggt
    11221 agaaataaag tagtatataa gtaattatat actatataaa taagaggtat aaatatgaaa
    11281 caatcaatag ctatagtaac tgataaaata actaaactat catctttctt agaagaaaat
    11341 atacgtttgg ttttaggtaa ttatattgat ataaaccact attatctgga agttttaaaa
    11401 gagaatgata aaatacaagg tgattttgta ctagtaatga atgatgatag attaaacagt
    11461 atgagaaagc atttagtaca agatagtaag attatagtga taaggagaac acttaaagaa
    11521 aatgaaatat atggattatt ttcaatacca aatggaactg aagtattggt tgtaaatgat
    11581 acaaaagaaa ctaccttaga aacgataagc ttattttaca aaataggagt aaaaaattta
    11641 aagtttactc catatattga aggaaaaatt tataaaaata tagacatagc tataacacct
    11701 ggagtaaagg gaaaagtacc aagttatata aataaagtaa tcgaccttgg aaatagatat
    11761 attgatatat ctacctttat agaaataata aatggtctta gaatagatgt taaagaaata
    11821 cgtaaaaatt taatggcata ttctgagagt ttaataagtt tagataatgg agttaaagat
    11881 aattataggc aactgttttt aaaaatagaa gaacaagatg ttatattgaa tctatcaaaa
    11941 gatggaataa tatttacttc agcagatggt ataataaaca catttaataa agaagcttta
    12001 aaaattttag gtataaatga aaatccacaa ggcaaaaaca tagaagatat catttctgaa
    12061 gatttaaata ttttacttga agacaaagaa ataattgatg aagtggtatt tacaaataaa
    12121 aaatatataa atgtaaataa aaaaagtatt ttttctatgg ggaataaagc tgggatatat
    12181 tataacttac aagaaataac gtatataaaa aaattagaac aaaatcttac taataaatta
    12241 agagaacaag gtcagatagc aagatataca tttaaagata taaaaactaa aaataaaaat
    12301 atggtaaagt gtgtagaatt ggctaaaaaa atatctaaat cagacctttc tgtattaata
    12361 ataggagaaa gtggtactgg taaagaatta ttatcacaat caattcataa tgattccaat
    12421 agaagtaatc aaccgtttat agcagttaat tgtgcagcag ttccagatag tctattagaa
    12481 agtcaactgt ttggatatga aaaaggctct tttacaggag ctttaagaga aggaaaaaag
    12541 ggtctatttg aacttgctaa taatggaact atatttctgg atgaaattgg agatatgcct
    12601 ccattgctac agacaaagtt actaagggta ttacaagaaa agcaggttat gcctataggt
    12661 tcccataatg ttataaacat agatgttagg gtcatagcag caacaaacaa aaacttacta
    12721 aagatgatta gagaaggaaa atttagagag gacctgtatt atagactaaa tgtattgcca
    12781 atagatgtac catcattgag gaatagaaaa gaagatataa taacacttat gaatttcttt
    12841 ttgaaaaaca atataagact ttcgccagaa gttataacta ttttagaaaa atataattgg
    12901 ccaggaaata taagagagtt acaaaatgtt gcttcttatg taagtctaat gtgtgatagt
    12961 atggttttta gagatgactt accaccatat ataagggtag aatgtgctaa caattatgaa
    13021 gatggatttg gttatacaag aaaagaattt gaggaaatac tgaggattct atatgaaaga
    13081 agagagtcat cctctggaat tggaagaggg tttataatcg aaaagcttat acaggaaggt
    13141 attgagattt ctgaaagcaa agttagaaag gtgctatctt atttaagtga atgtggatac
    13201 atatcatcta aatctggtag aggaggaagt caaataacct cagaggggat aaaactttat
    13261 aataatataa attaagctaa gtatttgata ttgaaatcac atattttgaa tttagatatt
    13321 taaataataa taaactttta tatttataga gattaattta tattatgtca gaaagaatat
    13381 tgtaatttat aattaaatat taataggttt ttaaaatagg attagatagg taataggtta
    13441 agttagaata acccattacc tatttttatt tgtaagaaaa gtgtacatag aattagaagt
    13501 aaaaaataca actaataaaa ctattgaaaa tactagataa ataataaata aaaataatta
    13561 tagattttgg catacatatt gctaattata gagataagac gacaaaataa ttgggaggtt
    13621 taatgatgaa atacaaaaca acagggactt gtgctacaga aattgaattt gaagtaaaag
    13681 aaaataaagt tacaaatgta aactttatag gtggatgtga tggaaattta aaagggctaa
    13741 aagtattagt tgaaggcatg aatatagaag atgtaataca aaagttaaaa ggaatagagt
    13801 gtaaaacaaa gccaacatct tgcccagacc aactgtctct agcattggaa aattatatga
    13861 atataaagta atacataaaa caatcgatta gttaggagtt taattatgaa accaataata
    13921 gggattttag gaaatttaat aataatggaa aatggtatgt ttccaggtct tgaaaggtca
    13981 tatgtaaata atgattatat aaatgcagtg ctaaaaggtg gcggtagtcc agtaataatt
    14041 cctgtaaata cagataaaga agttataaaa aaacagattg aaatggttga tggagtctta
    14101 atatctgggg gatgggatat caatcctcaa ctgtatggag aagaaacaag agaagaaacg
    14161 acatttatat atccagaagt ggatgaattt gatttaattg caataagtat agcattagaa
    14221 cttaaaaagc ctatattagg tgtatgtagg ggactacaaa ttttaaatgt aagtttagga
    14281 ggaactttat atcaagataa taatcttata gaaggaagtt atataaaaca tacacaatct
    14341 tctaaaagac atgtagctac tcataaagtt gatgttaaag aaggaagtat tttagaggga
    14401 attttaggaa aacaattact tacaaatagt tatcatcatc aaagtgtcaa tcagcttgga
    14461 aaaggattaa aagccatagc atactcaaaa gatggtataa tagaagctat tgagaaagag
    14521 gatgaaaatt ttgtagtagg agtacagtgg catccagaaa tgatggtaga ttactgtgat
    14581 aaaatggaaa aactatttaa atattttata aatatttgtt cgaatttata atataccttg
    14641 gggggattga acatgaacga aaagaacaaa atgggattaa taagtattat acttttaggt
    14701 attaatgcag tagtaggagc tggagttttt ctattaccag gagatgcaat gaaatcattt
    14761 ggtgtagcaa gtatatttgt atatatattt gatatgttgt tagttttatc tatggcattc
    14821 tgttttgctg aggttgcagg taaattcaat aaaaatggtg ctgcctatgt atatacaaaa
    14881 gaagcttttg gagatttttg tggttttgaa gtaggtctta tgaaatgggt aataggatgt
    14941 atttcttggg gagctttaat agtaggtttt cctacatcat tatcagcagt atgggctcca
    15001 gcaggtgaac cacatataca aaaaattata attgtagcta tgatagttgg gcttacaatt
    15061 ataaacttat taggtgtatc tctatcaaaa attgtacaaa atgttataac tgtaggtaaa
    15121 ctaattccat taatactatt tataggaata ggtatatttt ttataaaagg agttaatttt
    15181 acttcttcaa caatggtacc tccaggagct ggagcaacag agtttggagc agcagcactt
    15241 ttaatgtttt attcatttac aggatttgaa tctatagcag ttgcagcaga agatatggaa
    15301 aatccacaaa aaaatatacc aatagcaatt ataagtgtaa tagtaattgc atcaataata
    15361 tatatattaa atcaagttgt atgtgttggt atactaggag attcgttatc tagtacatct
    15421 acaccagtgg cagatgctgc aagaatatgc tttggaaata tgggagctgg attggttacc
    15481 tttggaacat tggtttctgt tggtggaatt tgtatgtgtg gtgcttttgt aaatccaaga
    15541 agttgtgtag ctttagctga tgataaaatg ttaccgagaa tatttgcaag aaaagataaa
    15601 aaaggtacac catatgtagc gataatagct actatgttaa tcactatacc aatagctcta
    15661 tctggaagtt ttgctgaatt agcagcaata agtgcagttg ctagattcat acaatacata
    15721 ccaacatctt tatccgtatt agtgtttaga aagaaaagac cagaattagt aggtactttt
    15781 aaaactcctt ttggagcagt gattcctcta attgctgtat gtgttggaac atggttgtta
    15841 ttccaagcat ctatgcatca attaattatg ggattaggag ctttggcaat tggagtacca
    15901 ttatacttta taatgaagtc ttataataga aaaatctatg gtgaaaattt aaagaaaata
    15961 gtttaattat gttataacaa tttattgagt taaaattaga cattggcaga aaattaaata
    16021 caaataagta tctacaaggc tatattaaaa tattattaat tttttatttt aatatagcct
    16081 tatattgtta tcaataaatg aaaaatattg taacaacaga agaacaatag tattatgttt
    16141 atagacaaaa aacttattag gaggtaaatt tatgccaaca ataacattaa aaaatggtgt
    16201 agacgtactt attagagaag gtgtaagaga agatgctcaa agcattatag atttttataa
    16261 tgaagtgggt ggagaaactc attttctgtc atttggaaag gatgaatata aaatatcttt
    16321 ggaggaacaa gaaaatgcta tagaatcagc aaaagcatct gataattctg ttaaactgat
    16381 tgcatttata gatggtgaaa tagttgggat tgcaacgatt gattctaatc aaaaagcaaa
    16441 aggaaagcat gttggagtat taggaattgt tgtaaaagaa aaatattggg gaattggatt
    16501 gggtaaaagg cttatgttag accttataga atggtgtaaa tcaaatggaa taaccaagaa
    16561 gataactctt gtcactaatg aagaaaatta taatgctata ggattataca aaaaagttgg
    16621 atttgaagta gaaagcatac taaagaaaga atgttattat aatggtgttt atactgattt
    16681 aataggaatg tcacttttat tgggaatata attagtgtac attttatctc gaaaaaagta
    16741 tattaagtat ggtataatta aaaaagaata taacttaata taattttgga ggacgaatta
    16801 tgaaaaatct gtgtaaaata tcagatgatt atttaaacag caagcttaag tatttaaagt
    16861 tattatcaaa acaatatcca agtatatcaa aagcaagtac agaaataata aatttagagg
    16921 ctatattaaa tcttccaaag ggaacagagc attttataac agatgtacat ggtgaatatg
    16981 aaccatttgt acatgtatta aaaaatggtt ctggtgtaat aaagagaaaa atagaagaat
    17041 tgttttcaaa tacaataaga gacagcgaaa aaaaaatgtt agcaactctt gtatattatc
    17101 ctgaacaaaa gttagaccta ataattaagc aagaggaaaa tatagatgat ttttatagaa
    17161 taaatattta tagacttata gaactttgta aatatgcttc tagcaaatat actaggtcta
    17221 aagttagaaa actgttacca gaaaatttta aatacataat agaagaactt ttgcatgagc
    17281 atgttaaaag tgaacataaa gaagagtatt ataaaagtat agttgaaaca atagttgaca
    17341 taggaatagc taaggagttt ataattgcta tttctacagt tatacaaaaa ttggttgtag
    17401 atagacttca tgtaatagga gatatttatg atagaggtcc aagaccagat ataattgtcg
    17461 ataagcttat tgaacatcat tgtgtagata ttcaatgggg aaatcatgat atattgtgga
    17521 tgggtgcagc ctcaggtgaa aaaacttgta tagcaaatgc actgaggata tcagctagat
    17581 atgcgaattt agacattgta gaagacatat atggaataaa tctattgcct ttagccactt
    17641 ttgctataga aatgtataaa gatgaccctt gtaaagaatt tattccaaag gttaatgacc
    17701 aaagtgtaac aacaacagaa aagtctttaa tggcaaaaat gcacaaagca ataagtataa
    17761 ttcaatttaa gcttgaaggt gaggttatca gacgaagacc tgaatttgaa atggaacata
    17821 gactcttgct taatatgata aactatgatg aaggtacgat taatttaaaa ggtaaaacat
    17881 ataaattaaa agatacttat ttacctacaa tagacaaaaa agacccatat aaattaacta
    17941 tggaagaaag aaatgttatt gataaattag tatcttcatt tagaggtagt gaaaaactac
    18001 aaaaacatgt ttcatttttg ttttctaaag gaagtatata tttaaaggct aactcaaatt
    18061 tactgattca tggatgtgta ccgttaaatg aagatggaag ctttatgtct atgaatataa
    18121 tgggaaaaga gtataaaggt aaggctctta tggataagat ggagtctcta gcaagagaag
    18181 gatttttctt taaagataag gcagaagaaa aactgtatgg catggatatt atgtggtatt
    18241 tatggactgg gaaatgttca tcattatttg gtaaagatga tatgactaca tttgaaagat
    18301 actttatagc tgaaaaagag actcataaag aaaataagaa cccatatttt aaacttagag
    18361 aaaatgagat ggcttgtaaa agattatttg aagaatttga tttagaactt gatgaatctc
    18421 atataataaa tggtcatgtt cctgtggaga gtaaaaatgg agagagccca ataaaagcta
    18481 atggtaaaat tctcgttata gatggtggtt tttctagggc ttaccaaaaa actactggta
    18541 tagctggata cactttgata tacaattcta gaactttgca attagtatcg catgaaccat
    18601 ttaattctgc tgaagaagcc attgcaaatg aaagtgatat cttatcgaca actgttgtag
    18661 tagagcataa ggcaaagaga aaaatggtga gagatactga tgaaggaata aagatacaag
    18721 aggaaataga agatttaaaa ctacttttaa tggcttataa gaaagggcta ataaaagaaa
    18781 tgtagatgtt atagaggcac ttcatgattg aagtgtcttt ttgttaatac ttattaaata
    18841 tattataaag attaataata gtagtttata ttatacttac taagtgaatc caagataaat
    18901 gggttcactt tttttattta taaacattat taaaaaaata tagatgtttt ggttatattc
    18961 cttgtccttt ataaatagaa ttatataaac aaaggaggag gacaagagat gaataaactt
    19021 tctgatgaaa taataaactc tctttctaca actataagag aaaaggtaga aaaagtctca
    19081 aacaataatc tgaacataga agaaattagg ttacgctcac aaaaaccatt gatactaaat
    19141 gcaaactcta aagattattt ttacaatcaa aaaactatga cacttgattt aaatcaacaa
    19201 aactcatatg tagtaacaag agaagatgta gagcaaactt ttcaaataat atgtaaatat
    19261 tcaatacatt catttatgga tgacataaaa aaaggattca taactttgag aggaggtcat
    19321 agagtagggt tagttggaaa agcaatagta gaagatggac aagtcaaaaa tataaagcat
    19381 atatcatctt taaatataag ggtatcaagg gaaattattg gatgctcgga taagatttta
    19441 agtcatatca taaagggaaa aaatcagatt aataatactt tgataatatc accacctcaa
    19501 tgtggaaaaa caactttaat aagagatata gtaagaaatt taagtaatgg taatgaagat
    19561 tatggattta aaggtttaaa agtggcttta gtagatgagc gtaatgagat agcaggagct
    19621 tatctaggtg ttccacaaat ggatgtggga ataaggactg atataataga aacttgccca
    19681 aaagacttgg gtattacaat gcttttaagg tctatgtcac caaatgttat tgtgacagat
    19741 gaaattggaa gtgaaaaaga aataaaggca ttatacacag cattaaatgg aggtatagga
    19801 ttaataacta ctgtgcatgg agattcaata gaggatatac aaaatagaaa agaattaaat
    19861 agacttctgg ataaagagtt atttaaaaag gttataattc tttctgcaaa aagaggagca
    19921 ggaacaattg aaaaaattta tgatttagaa gaaaagagat ggtattttgc aaattaaaat
    19981 aattattata gctttcttga taggaagtag ttatttgata ggtgaacaaa tatacaaaac
    20041 ttatactcgt agacataaac aattaaacga tttaataaga gttttagaaa ttttgaggat
    20101 ggatttatct tttggacttt atacattaga agaaatcttt aataggatag gtggaaataa
    20161 agagttttgt ttttggaaat ttttctatca aatatcagaa ggacttcaca atgaacaaag
    20221 taaaactttg gaaataataa tatcagaaaa tattgatgtc ttaagtaaag aaacttatct
    20281 aggcaataaa gaaattgagg aactgaaaaa tctaatactt actttaggga aaagcgatat
    20341 agagtcacaa caaagaatga tagatttatc tatagaaaat ttgaaaaaac aaacctatga
    20401 gacaaaggaa gatataaaca aaaaaggcgt attgtataaa aaattagtga cattcatagg
    20461 tataggtata tgtattatat tgatttaata tggggaggtt tattatggaa atatcattga
    20521 tattaaaggt tgcaggtgtc ggtattctaa tatcagtatt gaatatgata ttggaaaaaa
    20581 cagatagaaa agattgggca ggtcttacta cattagcagg tgtaataatc gtattgggta
    20641 tggtaataac agaaataagt gacttgttta atactgtaag aacaatgttt caactttact
    20701 aaagaggagg gagtaatttg gaaataatgc aattaatagg aattgcaatc atttcaacta
    20761 cactctgttt agtaattaaa aaagatagac cagagatagc aaatttcata gctataataa
    20821 ctggagtaat aatactattg tcagttatgt ttaagctaaa ttttatagta gatagtatac
    20881 aagatttggc taacaaggct aacatcccaa ctatgtatat atcattaata ataaaattaa
    20941 ttgggatagc atacttaatg gaatttgcga tacaactttg taaagattgt ggggaaggaa
    21001 acattgcttc aaaactagaa tttggaggta aaataatagt tatgtcaatg tctttcccta
    21061 tacttttgtc cattgtagaa atggtggtga atataattcc atagatgtgt atcttggaat
    21121 gaatataagt atattagaga gctttcgttg tattgaggtt tatagagtga agagaggcat
    21181 ggttgcttat gaaaaaaaga tttttaccaa tgattatagg ttttttattt actttctttt
    21241 ttgtaaatat ctttgctatt atgatatttg ctaatgaagt accaagtagt gaagataaag
    21301 aatatggtga aacaaaaaat agcatagata agtatataga tggtcaatta gacaagctag
    21361 atataaatga gattcaagac tatataaata aagaaatagt tattaatgat gttaatttaa
    21421 aatcatttgt aaaagattta attagtggag aaaaaaatat cttagattta ttcaataaag
    21481 atggattgaa gatattgatg tttgatgaat ttaaagcaag tttaaaggta gtagcagtaa
    21541 ttttggtact ggctctgtta tcatctattt taaagagtct ggaaaactct ttttcatcag
    21601 gtgcagtaag tcaaatagca acatatataa tatttatcac aatggtatca cttacactta
    21661 ttggttttaa agatgtatta cagatttgct atgatgcaat agaccatact gtaggtctta
    21721 tgcaagttat aatgccaata ttaataacat ttttactttt aattggattc ccaataacgt
    21781 cgactacttt gaatcctatc ttcataggag gagtaacatt tataaatgta ttttttaaaa
    21841 attttctatt tgtatctatt actgttgcat ttggaatttt aataataaac aatttatcaa
    21901 aaaatataag gctaaagaga tttttctcct ttgtaaaaca aataaattat gtttctattg
    21961 gagctatgtt tactgtttac ttaggtcttg tatccataca aggattgtat gtaaccagtt
    22021 ttgataaatt cagtgtaaag actgctaaat ttgctatagg taattttatt cctgttgtag
    22081 gtggatttgt atctgactct gtggatattt tattatcttc atctcagctt ataaaaaata
    22141 tatttggagg aataggactt atcttacttg ttggaatttg cttacttcca gtaataaaaa
    22201 ttttatcagt aatagtagtg tacaaattag cagcaataat tgtagagcct gttggagagg
    22261 atggaatatc taatttttta aatgaagtgg caaatttaat gataataatg ctagcatcag
    22321 taattgctat aacagtaatg ttctttgtaa ctgtagctat cttgacctcg ataagtgtcg
    22381 taagtcaagg gtaatttata tatcagtgaa aaataattac atttaatcta atgtttttag
    22441 agaggaggat gctatgttag agggcataaa ggcatggata gttagtgttt tgataggagc
    22501 atttatagta aatatagtag atatgatttt accaagttct aagataaaac cttatgtcaa
    22561 cctagtttta aactttatgt ttgtatttat tgtaataact ccagtagtag gatttttttc
    22621 aaaagatatg agtttagaag atagaatatt aaaatctatg ggaaactaca acaagcagta
    22681 tgtagatagt acaaatgctt tggcaaaaga gactggaaat aatagtctat ccaagggata
    22741 tgaggatggg ttaaaagaag tacttaaatt aaaacttgat gaatatggtt atgatttaga
    22801 agatatagag cttaatgggg caaatataaa taatataaaa ataaaagaaa agaataatag
    22861 tgcaaaaagt aataacagtt ccaatgaaga aaataaaaat aatagtacta aaagagagga
    22921 agaaaacata aactctaatg acaaagaaaa ttctaaacaa gtcttcaaaa aaggtacaga
    22981 gtatgggttg aacctaaatg aagaaaaatt aaaaaacgac ttaataaagg tgctggatgt
    23041 ttctatagaa gatatacaaa ttgataaata ggagttggga gaatgttgaa aaacttaaat
    23101 gacaaagata agagaaaggt atattcacta ataactatag caggaatatg tgtggtttca
    23161 ttagtattat tatcttgttt tcctagtagc aaaagcgata aacaagttgg aaaaacagag
    23221 actaataaaa atgctgaaaa gcaagtcact aaagaacaag aaaaagatga tttagagtca
    23281 aaattaacag caatactatc taaaattgat ggtgcaggag acgttgatgt aatggttaca
    23341 tttgaatcaa gtgaagaaat acaacctgct tttaattcaa ataatacaac agaaacaaca
    23401 gaggaaaaag atgcacaagg tggagaaaga acagttacga cttctagtga aaataaaaca
    23461 atgataactt caaattcaag tgaccctgta gttataaaaa ctacagagcc aaagataaag
    23521 ggagtgatag tggtagcaag tggagcaagt gacccaagtg ttaaagagac actttatagt
    23581 gcagtacaaa catcattaca agtagctggt catcaagtag aaatatattc taaataaata
    23641 catataaccg gggggataaa tgaatgaagt ttaattataa gggaagagga tttgtaataa
    23701 taactttaac tgcaatgtta gtggtagtag gaacagtgaa ttatcaacta agtaagaaat
    23761 ctttattaga aacatcaaaa gagtttaagg catatgaaga agcacagttg caaaaaaata
    23821 ctgatgagag tgatagtagt aagacagagg attctagtaa tgtagataaa caagatggta
    23881 aggaaagtgc tgatattgat atagttgata gcaaagctag taaagtaaaa gaaaaggcaa
    23941 ctgagacaag taaggaaata aaagctcaat tatcatcaga gaaaaatatg aaaaaggcat
    24001 cttatatttt agatatgaaa atgaatagag aaaaacaaag aaatgagtta gttcaagatt
    24061 taaatgaaat gataaataat ccatctacaa cagaagaatc tagaaaagaa gcttctaata
    24121 tgaaattaaa tatagttaaa attcaagaaa aagaacttca aatagaaaac cttttgagta
    24181 caaaagggta tgaagaagcg ttagtttata taagcgataa caaagttaat gtagttgtaa
    24241 atgaagctaa attagaaaag aaagatgcag caaaaatatt tgatttagtt gcagaacaag
    24301 ccaatgtgaa gtatgaaaat attaaactta caaataataa tagtaataag taaagtataa
    24361 acctcagaat taactgaggt tattttcttg caaagtagac ttgtatttgg tattattata
    24421 cttataaaaa tagttcctta aaatcaggag gtaagtttta atatggaaga taataaattt
    24481 ggacaagtaa aaatatctaa tgatgtaata gctacaatag ctggtttagc agcattagaa
    24541 gttgaaggca tagaaactac agcaacatta acagataagt tgttaaaaaa taatggagta
    24601 aaaatacaaa tcgaagaaga ggatgttaat ttagatgtaa tggttacgat aaagtatgga
    24661 atgtcaatac cagatacagc ttttaaagtt caagaaaatg taaaaaatac tgttgagaca
    24721 atgacaggac tgaaggtttc tcaagtaaat atacacattc aaggaatcag ctttaagaag
    24781 gataaagttg ataaagaaga agcaaaagca actaagaaaa attaatatta gccctctgaa
    24841 aagtcagagg gttttttgct ggtaattgat tttatatgga taattaaact taaaggagaa
    24901 ttttgattga tgaaaaaaga tagggcacaa aagagtacaa caagagaata tataatgaaa
    24961 cttatatacc aaataaatat taataaagaa gattttgaaa ctttagaaga taaagtagat
    25021 aattttttaa aagataattc agaacatatt ataaatagat ataaagaact tgcacttcaa
    25081 tactcaaaaa atacaaattt aaagttagaa gatactgaaa ttgaagatgt tatagacaaa
    25141 aaatatataa atacagtatg caaagcattg aaagaaaatc atgacaaaat agatgagtta
    25201 ataaataagc atgctaaaaa ctggacagta gatagaatgc caaaggtaga tgtttctata
    25261 cttagattgt ctgtgtgtga aatactttat ttagacactc ctaataaagt atcaataaat
    25321 gaagcagtag aacttgcaaa aatatattgt gatgataagt ctcctaaatt tataaatggt
    25381 atattgggaa gtgttgttga tgaaattggg aaataatata ataattggaa ttgatactag
    25441 ctgctatact acttctatag cagctatctc tttagataag aaagttatat tcaatgaaaa
    25501 aataatgtta gaagtaaggg ataattcaaa aggtttaagg caaagtgaag ctgtatttca
    25561 acatatcaat aatttaggga ttcttagtga taggataaaa tcttttaaag ataagtttaa
    25621 tgtagaagga gtttgctcat caaaaaaacc gagacctgtt gaaaactcat atatgcctgt
    25681 attcaatgta ggtcataatt ttggaaaatt attgtctagt atatatggtt gtaggtttta
    25741 tgagactact catcaagaga atcatattga agcaagttta ttaaatagta aattaaaaaa
    25801 taataataaa tttatttctg ttcatatgtc tggtggtact acagagatac ttttaacaag
    25861 caaacaagat agtcatcaca atgtatgtga tactaattta ggtaaaattg ccaaaataag
    25921 tattaaaaaa gatgataaaa gtaagttata caataatttt ggatataata tagatataat
    25981 tggaggaagt aaagatatta gctttggtca acttatagat agagtaggaa ttaagcttgg
    26041 atataaattt ccttcaggaa agtatttgga tgaaaatgct ttaaattgta atcttaaaat
    26101 agaaagtggt ctgaaaactt ctgtaagaga tgggtatatg aatttatcag gattagaaaa
    26161 tcaggtaaat aagattataa atgataatgg agataatact aatcaaaaag aatatatatc
    26221 taaattggta ttagattcag tagttagaaa tatgtttaaa tctttagtgt atttatgtga
    26281 aacttataat gtaaatgaag tagtatttgc tggtggagtt tctgcaagta agtatattct
    26341 tagagaatta agcatgaagt taagaaaaaa gcatatagaa gcttatttta cagaaccaca
    26401 atattcaact gataatgctg tcgggtgtgc tataatagga ttgaataact ttttaggaga
    26461 aagagtatga aactaagagc tttagatata agtgaagcaa actcatatat taaaagaatt
    26521 ttaataaacg acccaatact ttctaatctt aaagttaaag gagaaatttc taattttaag
    26581 gttcatagta gtgggaatgt atatttatca cttaaagatg aaacatcaaa gttaaactgt
    26641 gtaattttta aaagtaattt taatcgcaat ttaaaattag ataatggtgt aaaaattata
    26701 gctaatggat atatatcagt ctatgaaaga gatggtgcgt atcaattata cattaatgaa
    26761 attgaaatag agggaatagg aaatttacac atagagttta atagattaaa ggaaaaactt
    26821 aataaagaag gattatttga ccctaaatac aagataccta tacctaaaat gccaaactca
    26881 attggcgtta taacatctcc aacaggtgct gttataagag atataataaa tgtaataaaa
    26941 agaagatatc cgaaagttaa tataaagctt tatccagtaa cggttcaagg agataaatca
    27001 gctgaagaaa tctgtgaagc aattagattt ttcaatcata tgaagaatgt tgatacactt
    27061 atagttggta gaggtggggg ttcgatagaa gaactttggt cttttaatga tgaaatggta
    27121 gcaagagagg tttttaattc tcaaattccg ataatatcag cagttgggca tgaaacggat
    27181 tttactattt gtgactttgt gtctgatatg agagccccaa cgccatcagc agcagctgag
    27241 attgctactc catcattgga tgatataaac tataaacttg gaaacataaa aagtaggatg
    27301 agtaagtctc ttacaaatca aatagagcta gaccaatata ggttagaaac agtatttaat
    27361 aagataaata actatttaga ttcgtacaca ataaaagata aagttataca attagacaaa
    27421 atatatgata aaataatttt tggaatagaa aataatttaa aattagaaga tgaaaaatta
    27481 gtaaaaattg gagcattact ccataattta agtccattag ctactatgga tagaggttat
    27541 agtataactc aaaaaaatgg aaaagtaata aatagtataa aaggattaaa aataaaggat
    27601 agtatagata tagtattaaa agatggaaat ttagaatgta tgatagataa aattgaaaat
    27661 aaagagggat agtatgaatt taacctacga agaagcttat aaaagattag aaagtatttt
    27721 aagtgaatta gaatctaaaa atgctagctt ggatgaatct ttaagcctat atgaagaagg
    27781 tataagcctt tataaacatt gtaataagct tttagatgat gctaaattga aaataagtaa
    27841 atttaatcaa ttgggaatag aagaagactt taaaatagag gaggaataaa attggaattt
    27901 aaacaatgtc taaaagaaaa agcaagtttt gtagaaaaag tacttaaaga atatatgcct
    27961 aaagaagaag ggtatcaaaa aactgttatt gaagctatga actatagctt aagtgctgga
    28021 ggtaaaagat taagaccaat acttacattg gaggcttgta aaatagttgg aggtaatgaa
    28081 gatgaagcta ttccttttgc tattgcaatt gaaatgatac atacatattc actaatacat
    28141 gatgatttgc cagctcttga caatgatgat ttaagaaggg gaagaccaac aaatcataaa
    28201 gtatatggag aagctatggg gattttagca ggagatgctt tgttaaacta tgcttttgaa
    28261 gtaatgcttg caggctcaat caataaagaa aatccagaaa agtatctaaa agctataaat
    28321 gaaattgcca aaggtgctgg tatatatgga atgataggtg gtcaagtagt agatgtagaa
    28381 agcgaaaata aacaaattgg aaaagaaaaa ttagattata tacatatgaa taaaactgct
    28441 gcaatgatgg taggctgtat gagagcagga gctactatag gtggagcaaa ttctgaacaa
    28501 atggaagaaa taactaaata tgcaaaaaat atcggattat cattccagat agtagatgat
    28561 atactagaca tagtaggaga tgaagctaag ttaggtaaaa aggttggaag tgatatagaa
    28621 aatcataagt caacataccc atctctttta ggtttagata aatctaaaga aattgcacat
    28681 aatttgattg atgaagcaaa gaaaagtata gaaaaattat ctgatgatgt agatttttta
    28741 aagggattgg ctgaatatat aatagataga gaatactaaa atatacagct aaaatcgagg
    28801 agggaaaaat ggattttttt tcggagattt ttaacaatgg ggctttggga ataagtctga
    28861 ttgcttgttt cttagcacaa tttataaaaa tatttactgg taaggaaaaa agaattgagt
    28921 tatcaagaat acttatttca ggaggtatgc ctagttccca tagttctttt gttacaagtt
    28981 tagctacagt ggtaggtatt gaaaaagggt ttaattctac tgattttgct ataattaccg
    29041 tgcttgcctt aattataatg tatgatgcag caggtgttag acgggctgtt ggtaaacaag
    29101 ctactatatt aaatcaaatg gtggcagata tacagcatgg aaagcatata gagcagaaga
    29161 aattaaaaga attaataggt catacaccac tagaagtttg gtttggagct ttacttggaa
    29221 tagtaacagc tttaatattg atgtaaattg aaaatttaca gaataaaggt gaggataata
    29281 tgtataaata tttagataaa gtaaattctc caaaggatat aaaaaatatg agtatagaag
    29341 aaatggattt acttgcaaag gatataagaa agttcttagt aaaatctgtt tcaaagacag
    29401 gaggacactt agcttctaat ctaggagtgg ttgagttaac attagcactt cataaagtat
    29461 ttgatagccc taaagataag attgtatggg atgtagggca tcaatcttat gttcataaaa
    29521 tagttactgg aagaaaagat tgttttgtat ctttgagaca gtttaatgga ctaagtggtt
    29581 ttccaaagga gaatgaaagt cctcatgata tttttgatac aggacatagc agtacatcta
    29641 tttctatagc tacaggtatt gcctgtgcta gggatataaa aaaagaaaac tatagtgtta
    29701 tatctgtgat aggagatggt tctataacag gaggtatggc acttgaagct ttaaatcaat
    29761 taggatatat agataccaat atgatagtaa tccttaatga taatgagatg tccatagata
    29821 aaaatgttgg aggaatgtct aaatatctgt caagtattat aagaaactca acagttgaga
    29881 aaatgacaga tgaagttgat aaaattttaa atgttacaca aacaggtgaa attttatcta
    29941 agactgcaca tagatttaaa gataaactaa tgtatagctt ttctcctcag gactgttcat
    30001 tttttgattc attaggtata agatattatg gacctataga tggccataat actaaagaac
    30061 taatagatat attgagaaaa gctaaacaca aaaaagggcc tgttctttta catgtaatta
    30121 cgaaaaaagg aaaagggtac agatttgcag aagaacaacc tgataaatat catggagtat
    30181 caaagtttga tataaagaca ggtgttacat ctgcaaaagt taagtctatg tcaattagtg
    30241 ttggagaaaa acttgttgat atggctaata gtaatgaaaa tatagtagca ataacagctg
    30301 caatgccatc tggtacaggg ttaaacctgt ttgaaagtgc atatccaaaa agatattatg
    30361 atgttggtat agctgaacaa catgcaacag gatttgcagc aggtcttgca aaaaatggta
    30421 tgaaacctta ctttgctgtg tactcatcat ttttgcaaag ggcatatgac caagttattc
    30481 atgatgtatg cataacaaaa aagccagtta cttttcttat agatagagct ggattagttg
    30541 gaaatgatgg agaaactcat catggtatgt ttgatttaag ttacttaaat tctattccaa
    30601 atattgtagt aatggctcca aaagacacaa gagagatgga gcttatgatg gatttgtcat
    30661 taaaattaga ttgtccacta gcaattagat acccaagagg aagtagttat tacctagata
    30721 agggagagta tggagagatt gtactgggta aatatgaggt attagatgac ggtcaagata
    30781 cagtcatact ttgtattgga agtatggtaa aacatgcttt agaggctaaa gaaatattat
    30841 caagagaagg aataaatccg acaatagtta atgctagatt cttaaagcca attgatgaag
    30901 gtatgttaaa agcattatta aaaaatcata aaaatgtagt tactatagag gataatattg
    30961 taactggagg atttggaagt agaataaata agtttattat agataatgaa tataacgtaa
    31021 atatacttaa tatagcaata ccagaagaat ttgtaaaaca tggcaatata gatgaattat
    31081 atgattttgt aggattatcg ccaaaaagta ttgctgataa aataaggaaa ttagttattg
    31141 agtaaaaatc taatgtagat attgtaaatt aaaatttata taaaatatag aatttatcaa
    31201 ttagaataaa tatcaagtgt gttacttcaa gctactttag ttatcattaa agtagctttt
    31261 aacagaaagg taattgtatg aaaaaaagaa tagatttatt attagtagaa caagggtact
    31321 ttgaaagtag agaaagagcc aaaaaagcaa taatggctgg attggttttt gttgataatc
    31381 aaaggtgtga taaggctggt acagaagtaa aagaagattg tagtatagaa gtaaaaggaa
    31441 atccaatacc atatgtcagt agaggtggtt taaagcttga aaaagcaatg aaaaactttg
    31501 atttgactat tgatggaaag gtatgtatgg atataggggc atccacaggt ggttttacag
    31561 attgtatgct caaaaatgga gcaataaaag tattttctat agatgttggt tatggtcaac
    31621 ttgcatggaa attgagacaa gatgataggg ttgtgtgtat ggaaagaacc aatataagaa
    31681 atgtgacaat agaagataca aagcagtttg ctgattttgc gtcaattgat gtgtctttta
    31741 tatcgttaaa gttagtactt ccaaaggcaa aggagttagt acgtcatgat ggggaagttg
    31801 tcgctttaat taaacctcaa tttgaagcag gaagagaaaa agtaggtaaa aaaggagtag
    31861 ttagagaaaa atctacacat atagaagtta taaaaatgat ttctgatttc tcagtcgaaa
    31921 atggatttga gattttaggg ttagattttt ctcctattaa aggtcctgaa ggtaatatag
    31981 aatatctaat tcatttgaga aatggaaatg aaggatatga atttgatggt gagacataca
    32041 ataacaaaat agtagaagtt gttgaagctt ctcataattt agacaaatag gttaaaaggg
    32101 ggcttagatt tgatcctcga attatatatg aaaaattgtg ccttagttga agaactaagg
    32161 ttgaatattg ataaaaactt aaatatactt acaggtgaaa ctggttcagg aaaatctata
    32221 ataatagatg cacttggact ttgtttaggt gataaatatg ataggtcttt tttaagaaaa
    32281 ggaacagata agggacttgt tgaggctgta tttttttcag acaatagata tcttaaaaaa
    32341 atattagaag aaaatgatat aagtatggaa gatgataatt tattggtaat aactaggttg
    32401 atatactcag atggtaagag tactgctaga gtaaatggaa ggactgttaa agtgtctctt
    32461 cttaaagaaa ttgcatctac acttatagat atacatggtc aacatcaaaa tcaagctttg
    32521 tttaataaag atactcattt aaaatttcta gacctttttg gagaaaatga attggaagag
    32581 tttaaaattg cttataaaaa tgtgtaccat aagtatagtg aagtaaaaaa agctttaaat
    32641 tgcttgacag aaaataaaga tgagatgcaa attcaacgag aaatagattt attaagattt
    32701 caaataaatg aaattgaagc tgcaaatcta aataagaatg aatatgaaga tttattaaaa
    32761 caaagagaag tttatagaaa tagtgaaaag atatataata atctaaattc gagttatagc
    32821 aagttacata atggtgagta taatgttatt gacctaatag gtcttgcatc taaggaactt
    32881 aatgacatat ctaaatatga cagtgtttta agtgaatata gtgatactgt agaaagaatc
    32941 atgtatgagt tacaagacat atctggtgag ataagaaatt acaaagataa tatagacttt
    33001 gaaccttatg agctagagca gattgagctt agaatcgacg agattaataa cttaagaaga
    33061 aaatatggag acagtataga tgatatattt gagtattatg gaaaaattaa agatagatta
    33121 gatgaaatat taaacagaga tgaaagagtt gaacagttaa gaagcaaact gatgaatata
    33181 gaagaagatt taaaaataaa agccagtaaa ttgactaaag caagaataga agtagcaact
    33241 actttagaaa aaatacttct tgatgaatta aaaagcttaa atatgaaaaa tgtaatgttc
    33301 aaggttaatt ttgaaaaagg tccatttact ttagatggag tagatgatat tgaatttatg
    33361 atatctttta acttaggaga agatattaag cctatatata aagttgcatc aggtggtgag
    33421 atgtccagat ttatgttagc gtttaaaacc atattggctg atatagatga tattgataca
    33481 ttagtgtttg acgagataga tactggaata agtgggatag cagcacagat agttggtgag
    33541 aaattgagtg atatagcaaa gaaaaaacag ataatatgta taactcattt acctcaaatt
    33601 gctgcaaatg cagacactca ttattgtata gagaaagata cttcaaataa taggacgttt
    33661 accaatgtta gtaagttaaa tgaatctcaa cgaaaaaatg aaattgccag acttatagca
    33721 ggtaacaata taacagaaaa aactattgaa catgcaagtg aaattattga gttggctaaa
    33781 aaatgttagt gaaaaacaag cattttaata ggtgtaaaga atttttatag aaatgcttta
    33841 catctatttt ttatgatgaa attattttaa aatatctagt gcctatattg aagaaaagta
    33901 gatttaaaaa tagaagaaaa tttgtataaa tttgtaactt tgaaatttct aaatgcttaa
    33961 gtataatatt atttattaag gtagtagtga gggggacata aaatgaataa aaaagatact
    34021 atgcacttaa tttttacaat tgtaattttt attttattat ggtatattgt ggtagcagta
    34081 agtgagatta ataaaaatat tgaaagttgt agtaataaat tagattattt gtcacaagag
    34141 attatgagta ctaaatcgga tattagtaat actataaatg aagaaatgtc aaaaagttat
    34201 ataacaaaga gtattgactt aaaagtaaaa aaaatcgaga aaaaagagtg tgttattgat
    34261 gtagatgttc aattaagtaa acttggaaaa aatggaaaag tattttttat gtataaagaa
    34321 gatagtgata aatggaatga aactgagatg acaaaacatg gagaattatc atatgcatgt
    34381 gaaattaaga taaatacagg aagtgaatat gactataaag tagttacaag tggagctata
    34441 tctgaaagtt ctgatgtgca aaaattgact aaatctgatt atatgcctga acaacccata
    34501 tttaattctg ggataagaga taatagagaa tactttattg aaatagtaga aaatagtaat
    34561 cttttcaatc atgagagtga aaagtcaaaa aataaagttt atgataatat tagattagaa
    34621 aaagtagata ttattgtaaa tgaaggaaaa aaagacacta tatacaaagc caaattagct
    34681 gaaggcttag atgatggcaa aactaataat tcaaatagaa atcaagtgaa ttatgaagta
    34741 agttttccta aaagggatat tgatgacata atttatatta aagctaaact tacatacaat
    34801 aatggagtag aatatacaaa ggatataact gaagatataa ctatgggatt acaagattta
    34861 gaaaaataaa tacatattta aataaatatt caaatagatt tgttcaataa aatagagtat
    34921 aaataaaact gtagtagttt tacttatact ctattaaaaa attataattt taattccata
    34981 tatctagccc cttcaattgg attataagta taaggttcta tatcataaaa accaaacttt
    35041 tcatataatc cttgtgcact tttcatgctt ggaagagtat ctaatctcat gtgtgtatat
    35101 ccaaattttt tagcttcttc aatgatttct tccaatagta tttttcctat ttttaatcct
    35161 ctaaattgat ttcttacata taatcttttt aattcacata ttttaccttc aagttttttt
    35221 aaagcaacac aacctgccaa attttcatca acaaatgcca atatcaatga gcctgaaggt
    35281 tttttatatt ttcctggaag tgtttttaat tcattattaa agtcttgaaa acataagtct
    35341 atatttagag aatttgaata ttcagtaaat agaagtttta cgttttcaag gttttctaaa
    35401 tctttttctt caacaaattg taaagttata ttttgagcca ttttatccgc cattatataa
    35461 acatgtttat ataatgactt cacctccttg atatatgtat atttttctta atatcaatta
    35521 gattttaata ccattacttt ttcaccacca tagtcaagct ctccattaaa ctcaaatcca
    35581 aaatctttat aaagcttaat agccatttta ttgtcttcga atatactaag atatagttca
    35641 tcacagttat attcattttt aagatgattt acaagaaaat ctaatgatgc ttttccatat
    35701 cctttacctt gatattttga atcaatcata aatctatcaa gccaaactct atcatcttct
    35761 aaacgaccat acatagcaaa tcctattaaa gaattttcat catatattcc aacaggtacc
    35821 caagctgtta taaatttaga ttcagcaata gaaagtgcat tgctttctat ataatctaac
    35881 tgacttttat ctacagacaa actaactaaa tcatgccaat tatttatgtc tgcaattctt
    35941 acatttaatt tcaagatatt accgcccttc aaactttttg ttacaatcta atactatcat
    36001 attatgtatt aaaaatcact tattaagatt ttaaataaac tttttaaatg aataaattct
    36061 caggaaaaag gaattataaa tacataataa tacagcatag gagtagatgg atatatgaac
    36121 aaaataaata aaaatttcaa aaatatttgg ataatattag gagctgtatc gatttttacc
    36181 atggttataa tttttaataa aaattgtaat gttaataaag agactcaaat agaagctttt
    36241 acaattaaga atcatgataa aaaatttgta tatcctatgg gaaatataat tggagtaaaa
    36301 gcaaatacag atggtgtatt ggtcttagga tatgaggaag aggatgtaga ctatattgga
    36361 ggcatacaaa tcggtgataa tatagtaaaa atagataata aaaggataaa aaatagtcaa
    36421 gatgtatcag agattttgaa taagattaaa aaaagtaaag ttgaagtgac ttttgagaga
    36481 aaaaataagt ataaaacaga agtaatagag actaaaaaag aaaatggcaa gtataaactt
    36541 ggattatggg taagagataa aatatctgga attggaacta tgacttttta cgaccctagt
    36601 atggaaaagt tcaaagcaat cggtcatgcc ataaaagatt cggatactaa tgaactatta
    36661 aagataaagc aaggatatat atataagcca gaacaattaa aaatagtaaa agctagtaat
    36721 gaaaaagtag gtaaaataaa aggagatttt aatgacagca atttaatggg taatttctca
    36781 aataattcag agttaggtat aagtggtaat attacagaaa accataataa agagtttaat
    36841 gtagcaaata aagaaaagca attaatagaa gttggaagac cgcaagatgt aaaaatagga
    36901 gatgcagtaa ttctttttga ggataaaaac aaaaatataa caagctatga tataaaaata
    36961 gaaagtatag tatatgataa aggaaattat agagatatgg taataaaagt agtagatgac
    37021 aagttattgg aatacacagg aggtatcgta caggggatga gtggagctcc aataatacaa
    37081 aataataaaa ttattggtgc aataactcat gtttttagag ataatccgaa aaaaggatat
    37141 ggtattttta tagatgaaat gataaaattg taggtgaggc attaaaaaat tttattattt
    37201 tatcaattat ctaggaggaa tataattttg gagtgtcgaa tatgctttag agtagataat
    37261 taggaagcaa ttgtgtaaaa agtttagttt tctgtaataa gaagatgttt tttaatgggg
    37321 ggatttttag tggaaaaaat caaaatagtt ttagcagatg acaataagga tttttgtcag
    37381 gtattaaaag agtatttgtc taatgaagat gatatcgata tattaggcat agctaaggat
    37441 ggaattgaag cattagactt agtaaaaaag acacaaccgg acttattaat actagatgta
    37501 ataatgccac atctagatgg attaggtgta attgaaaaat tgaatactat ggatatacct
    37561 aaaatgccaa aaataatagt actatcagca gtaggtcaag ataagataac tcaaagcgca
    37621 ataaatctag gagcagatta ctacatagta aagccatttg attttgttgt gtttataaac
    37681 agaattagag agctagtttc taatagagtt acacaagttg agccaaaacc tagaccagtt
    37741 caagagactc aaatgactag aagtgatttt gttaagaatg taggaaatat agagacagaa
    37801 atcacaaata taatacatga aataggagta ccagctcata taaaaggata tttatattta
    37861 agagaagcaa taaaaatggt tattgataat gttgagcttt taggtgcagt aacaaaagag
    37921 ttatatccaa gtatagctaa aaaattcaat acaacaccaa gtagagttga aagagcaata
    37981 agacatgcaa tagaggttgc atggagtaga ggaaaagttg acacaataaa tcaattattt
    38041 ggatatacgg tacacaatac taaaggaaaa ccaactaatt cagaatttat agcaatgatt
    38101 gctgataaat taagattaga acatagtatg gttaaataaa caagacataa aaagtaaggc
    38161 tttttaatta aggcattggc tataaatgcg tattacaagc agcgaaacgg tataaccact
    38221 agggttatac cgtttcgcta ttttaataaa tataaaaatt ttctttatta tttgcttact
    38281 atatcaatat aataatttta ttatactatg gatatagtat gtgtctttac aagttgtaaa
    38341 ctgacagtgg tttatttttt aatataaata ttgactttga tgcaggtaaa ctttgtattt
    38401 ttaagcgtat tatggaatat gttaaataaa aaaatgatga aatatagtat tgtaaatgcc
    38461 aaagatgcaa aacaaactta aaacatttat tttattgtta agtaatgcta taatataatg
    38521 tgattttaat aatgatagtg gaggtttaaa tatgagagtc gaggccccta taaaagtaga
    38581 tcgaaaaacc aaaaaacttg ctaaaagagt tgaaagtggg gaaatagcag ttataaatca
    38641 tatagacata gatgaagttg ctgcaaactc tttagtagaa gctaaaataa aacttgtcat
    38701 aaatgcggct ccttctataa gtggtaggta tcccaataaa ggtccaggga tattaactga
    38761 aaataatata ctaataattg ataatgttgg agaagagtta tttgaagaat taaaagaagg
    38821 agaaactata gaagttgtag atggaaagat atatagaaaa ggaaaatttt taggtgcagg
    38881 agaagtttta gacaagtatg aggtttcaca ccaaataaag gctgcctatg agaatttagc
    38941 tgtagaattg gatagattta tagataatac tatagattat gctaaaaaag aaaaaggatt
    39001 tatacttgga gaagtagaaa ttccaaaagt gaaaactaat tatgctaata aacatgtatt
    39061 gatagttgta agaggtcagg actacaaaga agatttaagt actatgcttt cttatataga
    39121 agaggtaaag ccagtattgg ttggtgttga tggaggagca gacgctttaa ttgagtttgg
    39181 atatactcca gatgtgattg taggtgatat ggatagtgta agtgatgaag ctttaaaaaa
    39241 ggctagtgaa atagtagtac atgcttatac agatggaaga gcaccaggtc ttaagagggt
    39301 tgaggaatta ggcttagatg cagttgtatt tcctgcgcca ggaactagtg aagatatagc
    39361 tatgcttata gcctatgagt ataaggctga gttaatagta gcagttggta cacattcaaa
    39421 tatgattgat tttcttgaaa aaggaagaaa aggtatggca agtacttttt tagttagact
    39481 aaaaataggt tcaaagctta tagatgctaa aggcgttaat ttgttataca gaagtaaatt
    39541 aaaaataaag tacatatggg cattaatagc aacagcatta tttcctgtgt tggtagttgc
    39601 atcattgtca ccaggagttc aacagttcat acaactaatg caattaaagt ttagagtatt
    39661 attacagatg taaattttag gaggataaat atgcatatta atatgaaata ttatatagtc
    39721 actatagggg ctatatttat agctttgggt ataggcatgt tagtaggatt taatttaaat
    39781 aataatcaac aattaagtga acaacaagca aatataataa atgatttgga tgataagttt
    39841 aatatcttaa aagaaaaaaa tgataaactt gacagtgact tagcaagtgt aaatagagat
    39901 tatgaagagg cagttaattt tataaataaa aatgtagata agattttagc tggttcgctg
    39961 aatggtaaga gtataggaat aatatctgct aatgaaaatg acgattatac aaaaaatata
    40021 gaagacataa taaataaatc taatggaagc attgcattta atataatatt aaaagaaaac
    40081 ataacaaatc cagaaaagtt aaaggaaatg tcaactaaac taggtacaga tgtaaaaaat
    40141 gcaaatgatg cagttaatta tataattgac actcttaaaa aggaagatgc aagtgacatt
    40201 ttaacatatc ttcaagaact agatgtaata aagtttaatt ttattggaga tacatatcta
    40261 aaatatgatt ccgttgtaat agctggtgga aatgatgcaa aagacagtac aaaacagttt
    40321 gaaaaaatag aaaaatttgt agtttcaaaa cttaaatcag agaataaata tttagtagaa
    40381 gttcaaaata caggagttaa aacttcttat gtagaactat attctaaaaa caaagttgca
    40441 actatagaca atattgatga aggtatagga agtatatctc tagcgattct tctacaacaa
    40501 ggtaatatag ttggtaattt tggtagattg gatactgcaa cttcattgtt gccatctatt
    40561 aaatagaaat aattttaagg agagaaaaaa tggattctta tataagtata ataataccag
    40621 cttataatga agaaagtaga ataaaatata cattagaaag catattggac attaagcaaa
    40681 taaatgaaat aatagttgtg gatgatggtt caattgacaa tactgctaag gttgtatctg
    40741 agctagaaaa tgaaaagatt aaatttttta agttagataa aaatagaggt aaaggatatg
    40801 ctttaaatta tggtatcaag ttagcaatga aaaatgcaga tattataggt tttctggatg
    40861 gagatttagg aagttctgct aaagaagttg aaaaattaat agtacctata ttaaatggtg
    40921 aggcggatgt tacaatagcc aagtttcctc ctgcaaagag aaaaggaggt ttgggatttg
    40981 taaaaggttt agctaaaaat tctgtgtttg agatgactgg tgttgagtta gatgcaactt
    41041 tatcaggtca aagaatattt aaaagagaag ttttagaaaa gtttgatgaa ataccttttg
    41101 gatatggagt agaagttgga atgaccattg atatattaaa gtatggattt aaaattaaag
    41161 aagtattagt aaatatgact cataatgaaa caggaagaaa tttaaaaggt tttattcata
    41221 gagggaaaca gtattatcac ataaaaaagg ttttaggaca aaaaaagaaa gaatggaggt
    41281 aatatcttag tgaaagatta tatactttat accattttat tattaactgg attatttgga
    41341 acctatgctg taattccact atttaaaaat ttattgataa atggaaatgt acttagacca
    41401 aactataaaa aagatatgat accagtaagt atgggaattg tatttttgcc tatgattgta
    41461 atcaatggaa taatacttgc tttctttact acagaattta agaatttagc gtatatattt
    41521 atgtttatgt ttggtatgat atccatgttt tttgcaggga tactagatga tgtcattgga
    41581 aatagagatg taagtggttt aaaggggcat tttaaaagtt tatttaaagg aagtcttaca
    41641 acaggaggtt ttaaagcttt atttggtgga tttgtagggc ttatagtttc tgttgctata
    41701 tcaaaagaca taattgatat aatagtaaat acactaataa tagctctatc aactaattta
    41761 atgaatcttt tggatttaag accaggaagg gcaataaaag catatttatt cataatggta
    41821 attgtatttt taacattgac aggatttgtt caagttcttc cattacttat agtaccaaat
    41881 gtacttgcat actttaatta tgatttaaaa gcaagggcta tgatgggaga tactggttca
    41941 aacgtccttg gaatatctat tggaatgctc atttcttttg ggtatccatt taacattaga
    42001 ttaggatggt taatatttgt agttattatg catatattca ctgagaaata ctcattaact
    42061 aagataatag aaaaaaataa actattaaat tttatagata aattgggaag gtagtattat
    42121 gataagcaaa agagtgggga ttgttgaatc aatagtaagt caaactgaaa ctctagatga
    42181 tataagagta aatataaatg gagaaataca aaaggcatat aattatccaa aaatatctgg
    42241 aactataaat ataggtgacg aagtggtttt aaatacaaca gcagtagaac tgagcttagg
    42301 tacaggtgga taccattttg taataactaa tttaaataat atagaatcta ctttaactga
    42361 aggtggacat ataatgaaac ttagatatac gcctcttcaa ataaaagtgg attctgttga
    42421 ggaacaagaa agtatttatc atgataaatt tgcgaatttt aaaggattag aaggtctttc
    42481 tgttgtagta gggactcttc atagtatgtt aactccattt gcagcttcat ttaaaagaaa
    42541 taatccaaat aaaaaattag tgtatataat gactgatgga gcatctcttc caatttattt
    42601 aagtaaaaat gtggatactt taaaagaaaa aaaattaata gatagtacaa taactatagg
    42661 aaatgcgttt ggtggagatt atgaatgtat aaatatatat actgcattaa ttacagcaaa
    42721 agaaatacta aaagcggatg cagtatttgt cagtatggga cctggaattg ctgggacagg
    42781 aacaaaatat ggatttacag ggattgaaca aggctctatt cttgatgctg taaaaaaact
    42841 tgaaggaaga gcaattgcaa ttccaagaat tagttttgct gacaaacgag aaagacatca
    42901 aggtatttca catcatagta tgactgtatt taaagaaatt gtaaatgtaa atgtagacat
    42961 accaataact atatatgatg atgaaaaatt gaactttata aaagagcaaa tcaatttaaa
    43021 tggtttagac aaaaagcata atataattta tatagataat aataaaacga aagaggattt
    43081 agactatttt aatctaaaag taaagagtat gggaagaaat tatgaacaag atgaggcatt
    43141 tttcaaagct gcaagcacag cagcatatta cttaatggag gtttaagatg gtattagaag
    43201 aaaaaactat tagtagtgat agggtttata caggtaaagt aattacttta aaggttgata
    43261 ctgttgaaat tccagggcaa ggatatcaaa aaagggagtt agtagaagtt ggtggagcag
    43321 taggaatagt tgcaatcaca gatgataata aagttgtgtt agttaagcaa tttagaaaac
    43381 ctatagaaaa gccaatcttt gaaattccag ctggtaaact agaaaaaaat gaaagtccaa
    43441 aagaatgtgc tgaaagagaa ttaaaagaag aaactgggta tagtgcaaaa aatattaagc
    43501 taatacataa atttttcact tcagcaggtt tttctaatga gataatgttt gtatatttag
    43561 caacaggtct tactccagga gagaataatt tagatgcaga tgagttttta gatgtttatg
    43621 aaattgagct tgaagaagca tataacatgg tattaaaaaa tgacgttgaa gatgcaaaaa
    43681 catctattgg attattatta gtaaaagata tgtttaaaaa ttaatattta taaaatgaat
    43741 aaccctttgt cctaaagcat attattttat aaaggacaag ggggaattaa attgagaaga
    43801 acatatagaa aaaatgattt tagagaatta aatagacaaa taattattat aggattgttg
    43861 tttatgatgt ctattgttgt tgggtcttac ataaataaaa tattgccagg ttctagtaac
    43921 aatatattaa acaatataaa tcctgctgta gagtattata atctaaatat aagcataaaa
    43981 gatacagtga tacaaaattt aaaatcagat gcaatcttta tgggctcaat agctctatta
    44041 agtctatttg tagtaacaat tccagcagtg ttggtagctt ttgtattaaa agggatgtca
    44101 attggttata caataaatag ttgtatattg gcattaaaat ttaaaagtat aaaaatgatt
    44161 ttaataatat tatttaaaaa tttgattatt attccatgtg caatcatatt agcattaatt
    44221 agtttaagtt attttaaaga aatggtttat gaatttaaaa agaaaagtag aaaaaatatg
    44281 caatttttaa ttaagaggta tatactaaat attataatta taatagcact atcattgggg
    44341 ttgcaattaa tattaaatac tgcaagtatt ggtattatta agttcctagc taaataaagg
    44401 agtttataat ggatattata gagggatata tagattacat aaaagataaa aaaaaattat
    44461 cagagaatac agtggcatca tactttatgg atataaaaaa atatatggaa tatataaatc
    44521 aaaaaagcat taaactagta gatatagtag aaaatgatat tataagttac ttaataaagt
    44581 tggaaaaaga taatgtatca atagctacaa tagcgaggat gatatcctct ataaaatctt
    44641 ttcatgatta tttattttta aatcatatat gtacaaataa tcctgcaaag gatataaaaa
    44701 aacctaaaat aaaaaaagaa aatataaata tacttacaga agaagaaatt gaaagactat
    44761 taaattttcc aaagttaaca acacctaagt tgattaggga caaggctatt tttgaagtat
    44821 tatatggtac tggtataaaa gtatctgaat tagtagagat gaatatagag gatattgacc
    44881 tagatattga ttatatatat tgtaattcat gttgtaaaaa tcaaagagtg ataccacttt
    44941 gtgatattac aaaactttac ttagaaaagt atctaaaaga agcaagacct aaaatggctg
    45001 cagaaggtga aaaatcatta ttcgtaagtt cattaggtca aaggtttaca cgacaaggtc
    45061 tttggaaagt cataaaaaaa tattctaatc tagccaatat agataaaaat ataaatccta
    45121 caatgcttag acattcattt gctattcatt tgttaaatga aggtgctaac attgctgttg
    45181 taagtaaaat tttaggaaat gttaatttat ctagtttgca agtatattta aatcatatag
    45241 ataaaaacgt gagaagagaa ataaaggaga aacatcctag aaatgatgtt gatgtagaat
    45301 tacaaaaagc agaagctaaa tagactatat agcaaatttt ataatttaga aggagcatat
    45361 ttatatgagc agagtaattt ggattgtaat tgatagtgtt gggataggag cattacctga
    45421 tgctgaaaaa tttggtgata gtaaggatgt aagtaccctt ggaaatatat ttaaggaata
    45481 tccagatatt cagattccta atatgagaaa tttaggtata ggaaacatag aaggtataga
    45541 tttttttgaa agtataaaag aaccaatagg ttgttttgga aagtgtaagg aaatgtctca
    45601 gggaaaagat actactacag gtcattggga aatgactggt ataatagttg acaaaccatt
    45661 taagacattt gaacatggat tctctaagga gataatagaa gagtttgaga aaaaaactgg
    45721 aagaaaagta gtaggaaata aaccagcttc aggaactgta ataatagatg agtatggaga
    45781 gcatcaaata aaaactggag atgtaatagt gtatacatca gctgatagtg tatttcagat
    45841 tgctgctaat gaagaagtaa ttcccctaga agaactctat aatatgtgca aaatcgctag
    45901 ggaaataatg atgggggata atgcagtagc tagagtaatt gctagaccat tcataggtaa
    45961 gaaaaaaggt gagtttgtga ggacttcaaa tagaagagat tattcactag acccatttga
    46021 accaacagtt cttgataata taaaagaatc aggacttgat gttttagcag ttggaaaaat
    46081 agaagatatt tttaatggaa aaggaattac agatgctatc cacactaaaa gcaatatgga
    46141 tggagtggat gaaactttaa attatatgaa acaagataat aaaggtctaa tatattcaaa
    46201 tctcgttgat tttgattcta aatatggtca taggagagac ccagaaggat ataagaaagc
    46261 tcttgaagag tttgatagta gacttcctga aataatggct aatatgagag aagatgatat
    46321 tttaataatc aatgcagacc atggaaatga cccaacatat aaaggtacag accatacaag
    46381 agaatatata cctgttatga tttatggcaa taagattaaa aaaggtttta atttaggagt
    46441 aaaagatact tttgctgata ttggagcaac tgttgcagat atactaaatg taaagttgcc
    46501 taaacatggg tcaagcttta aagaagattt attttaaact ataaaatgat aaaaacttag
    46561 cttaatagga tggagagatt ggaatgtttg aaaagatagc acaaagtagt aaatttataa
    46621 attctaaaag taatataaaa cctaagattg gtttgatatt aggttctgga ctaggtgatt
    46681 tagcaaatga tatagaagac cctgtcacaa ttaaatatag tgaaattcca aacttccctg
    46741 tatcaacagt agcaggacat gctggacaac ttgtaattgg aaaacttgaa ggaaaagaag
    46801 ttattgctat gcaaggtaga tttcattact atgaaggata ttctcagaaa gaagctactt
    46861 ttccagtaag ggttatgaaa gaattaggag tcgagattct tatagtaact aacgctgctg
    46921 gaggcgtaaa taaagaattt aaagcaggag atttgatgct tataagagac catataaact
    46981 ttagtggaag taatccatta gtaggaaaaa atgatgacag atttggtgct agatttccag
    47041 atatgtcaga tgcatattct tctaaatatg tagatgtagt taaaaactgc gctaaagaat
    47101 gcaatataga tgtcaaagaa ggcgtttata tgttttttag tggtccaaac tatgaaacac
    47161 cagcagaagt gagaatggca caaattttgg gagctgatgc tgtaggtatg tctactgttc
    47221 cagaagtcat agtagcttct cactctaata taggagttat tggtatatct tgtataacaa
    47281 atatggctgc tggcatctta aatcaaccac taagtcatga ggaagtaata gaaactactc
    47341 aaaaagttaa atcagaattt atgaatttag ttaaaacaac ggttaaaaat ttataagtta
    47401 aagcttatta tagatttttt gaggaagttt ataataaaat agttaatgtt taatttgaaa
    47461 agaattaata aaaagctgtc ttgatataga aagttatttc taataaagga cagttttttt
    47521 ataatactac aacatttgaa agtgttttaa agtttaatat ttatttaaat tattataggt
    47581 tagaatggag atttcaatta tgagaatgta tgatattata aaaaaaaaga gagataacct
    47641 agagcttagt aaaaaagaga taaactactt tatagaaaac tattcaaagg gagatatacc
    47701 tgactatcaa gcttctgcac tattaatgtc gatttattta aataagatga ataaacagga
    47761 aactgtacat cttacagaag caatgatgaa ctctggagac atgataaacc tatctgagat
    47821 agatggaata aaggtagata agcatagtac tggtggtgtt ggagataaga ctaccatagc
    47881 tcttatacct ttggttgctt catgtggagc accagttgca aagatgtcag gtagaggtct
    47941 tggtcatact ggtggtacta ttgataaatt ggagtctata ccaggttttt cgacagaaat
    48001 ggagataagt aaatttattg attctgtaaa taagtctaaa atagcagttt gtggtcaaag
    48061 tgcaaaggta gcaattgcag ataagaaaat atatgctctt agagatgtta cagcaactgt
    48121 tgataatata tcattgatat catcaagtgt aatgtctaaa aagttagctt caggagctga
    48181 tgcaattgtg ctagatgtaa aaactggtga tggagcattt atgaagacat tagaagagtc
    48241 ttttgagtta gctaaatcta tggttgatat aggtactggt atgaatagag atacaatagg
    48301 gattgtaaca gatatggatg aacctttagg ttttgcagtg ggaaactctt tagaagttat
    48361 agaggcaatt gagacattaa aaggaaatgg acctaaagac cttgttgagc tatgcgaagt
    48421 attaggagca tatatgttgg ttttatcaaa ggtagcacat gattttgaag atggtgttga
    48481 aaaaataaga gaatcaataa aatctggtac tgctatacaa aaactcaaag agtttataga
    48541 gaatcaaggt ggtaataaag atgtagtaga tgattattct ttattcaaaa aatcaaagta
    48601 taaatatcca gttaaatcaa ctaaatcagg ttatataagc aaaattaaag ctgaagatgt
    48661 tggtgtatcg gctatgattc ttggagcagg tagagaaact aaagatgata ttttagattt
    48721 atcagcaggg ataattttag aaaagaaagt aggagattat gtaaatgaag gtgaagtttt
    48781 agcttacatg tattataatg atgaacaaaa gctttcattg gcaaagggaa gatttattga
    48841 ttcctactct attgtagatt caaaaataga aaaaaataaa ttaatatatg gtattgtaac
    48901 taaagaagag attaaaaagt tttagaaaat tttagaaaag tgattataaa aggcctaaca
    48961 tgtcaaaaat aatgttaggt tttttatttt ttgataaact ataaattata ccaaaaatat
    49021 atattttaaa acatttttta caatataaat aagtttattc tacaagatga ttgaaaatta
    49081 aagtatctag ttttataata gaaaatggat aaatatacat aaggagtaga ttatattatg
    49141 aactttaaag aaaatagatt gaaaatagca gtattaataa ttgttatttt gattatctta
    49201 gcaggtatat ttgtgtttat acaaataggt ccttatgata aaaataacaa aaaagatgta
    49261 attatcgacg ttccaagtgg agcatctgtt ggaaaaatat ctgacatatt atatgaaaat
    49321 aaattaataa agaatgaact attatttaaa cttttggtaa aggttagcaa taaagctccg
    49381 tctataaaat caggaacata cttacttaat caatcgtatt caaacaatga tataataagt
    49441 cttttagttt caggtaaaat atatcaggat ggtataaaag tgactattcc agagggagct
    49501 acatctaaag aaattatagc aatgttagta agtaaaaatt taggagataa agctactttt
    49561 gaaaatttaa taaaaaaacc tcaagaattt tatgataaat tttcatattt gaaggaagat
    49621 ggaataacct ctttagaagg gttcttgtat ccagaaactt attattttaa ttcaaagaaa
    49681 caatcagaag aagatatttt aagcgaaatg ttaaaagtat ttgacagtaa atacacggac
    49741 aagtttaaaa agaaacaaaa agaattaaat atgactcttc aagaagtaat ggaaatggca
    49801 tcaataattg agaaagaagc tgttcttgac aaagacagac ctataatagc aagtgtgttt
    49861 tataatagac ttaaggtagg tatgcctctt caatcagatg ctacaataca atatatattt
    49921 gaagagagaa agaaaattgt aacatatgat gatttaaaaa ttgattcacc atataatagt
    49981 tataaaaata agggattacc tcctacacca atatcaaatc ctggtataaa atctattgaa
    50041 gcagcattat atccagagaa aacagactat ttatattttg tagctaagat tgatggtgga
    50101 aataattata gtacaaacta tcaagaccat ttaaaatacg ttaaagaata taaagaagca
    50161 agggataaac aatcaaaaga tacaaaagca acaaataaag aaaatacaaa aaaataaacc
    50221 atgattataa aaagtctaac agggtaagaa taatgttggg cttttttatt gaaaattgtt
    50281 attcttagat ttataataaa gaaagtgtaa atatatataa caatatgaat ttaaaaaata
    50341 ataaattaat ataaaacttg gatatttatt attttaggga gtgtttttat gagtaatata
    50401 gttaatgatt tggttgaaga ttatataaga gtgacattaa aagaaaaaga aggattttta
    50461 aaagatttag aaatttatgc agaggaaaat agtgttccta taatacataa agaagtttca
    50521 gatttattaa aagtcttgtt aaaggttcaa aaaccaaaga gaattttaga agtaggatgt
    50581 gcaattggtt attcttctat tttttttgca actattatag gaaaagatgc agatataata
    50641 actgttgaga gaaatgaaaa aatgatagaa aaagcaaaag aaaacataaa attagctgga
    50701 tttgacaata acataactat actagaagga gatgcagaag aaaaacttag tcaagtccaa
    50761 ggtgaatttg accttatatt tatagatgca gccaaaggtc aatataagct attttttgat
    50821 ttagttatag ataaattaaa agatggggga cttttagtat ctgacaatat tttgtataaa
    50881 ggtatggttg ctcatgatga ttttgttgta agaagaaaaa agactatagt taaaagaatg
    50941 agaaagtatt tagattatat atgtaattgt gactatttaa gcacatcatt ggtaccaata
    51001 ggtgatggtg tagcactaag ttataaagaa agtaaaagag gtgatgtaga tggaattaaa
    51061 taaagtagaa cttttagctc cagcaggtga tttggagaga ttgaaaatag ctataacata
    51121 tggagcagat gccgtttata taggtggaga aatttttgga atgaggtctg cagcgaagaa
    51181 ttttagtaag gaagatatgg cagagggagt agcttttgca catgaaagag gcaagaaagt
    51241 attcgtaaca gtaaatataa tacctcataa tgaagatttt ctacaattag aagactattt
    51301 gttggaacta gaagagatag gaatagatgc agttataata gctgacccag gagtgcttag
    51361 tgtcattaaa aaagtaattc cgaatatgga aatacattta agtacacaag caaatacaac
    51421 caattatcta agtgcaaact tctggtacga gcatggaata aaaagagttg tagtggcaag
    51481 agaattatct tttgatgaaa tatatgagat aagagcaaaa acacctttag atatggatat
    51541 agaagcgttt atgcatggtg ctatgtgtat ttcttattct ggcagatgtt taataagcaa
    51601 ctatatgact ggaagagatg caaacaaagg ttcttgtgct caatcttgta gatggcaata
    51661 tcatttggtg gaagaaaaaa gacctggtga gtattttcca atatacgaag atgaaagggg
    51721 tacattcttc tttaactcaa aagatttatg tatgatagag tatataccag agttaatcaa
    51781 atctggtata acaagtttaa aaatagaagg tagaatgaag actgcatact atgtagctac
    51841 tgttgtaaga gcatacagaa tggcaataga tgaattttac agagacccag aaaactggaa
    51901 gtttaatcca atgtggatgg aagaactaaa aaaaggtagt catagacatt ttacatcagg
    51961 tttttacttg aataaaccaa caacagaaga ccaaaattat caatcagcat catatgttag
    52021 aaactatgat tttataggta tagttagaga aacagaagat gaagatggtc ttattgttgt
    52081 tgagcaaaga aataaaatgt gtgttggtga tgaaatagaa gttatgggac catataaaga
    52141 aactatgttt actaaaattg aagaaatgta taatgaagaa ggagaagcta tagaatcagc
    52201 tcctcatcct agacaaatag tgaagttaaa gctatcagta aaagttggta aagattatat
    52261 gcttagaaaa gttatagaag aaaaggttga agaataataa aaaattgata aaaatagtat
    52321 tagcccctta gaaattgtca ataatgaaat tatctaaggg gtgatttcat gtcaaaaaag
    52381 aagactccat ttttgaaaaa agtgggaaag agaagctggt gtatatttac tataatttta
    52441 ataatttata gtgttttaat ttataggcta gttgatatac aagtattaaa aggtgataaa
    52501 tacaaacaaa gtgttgaatc acaaagcgtt gagaaagtcg agttaaatag tggaagagga
    52561 ataatctatg atagaaacaa caagaagctt acagatacaa gtaaatctca ggtattaatt
    52621 gttgaaaaag aaaaattaaa taataactat aaaattttgg agcttattaa gaaagctact
    52681 aagatgaatg atttagatat atataaagct gtacaagagc aattgacacg ccctataata
    52741 cagattcaga ctaaaaatat cgatatcgat aagagtatga aaaaagaact tgagaaaaat
    52801 ggaataatgg tagaagaaaa aactatgagg tacgcaaaag atggtttatt atcacataca
    52861 ataggatata taaaagaaga tgataaatca ggtcaatcag gaattgaaaa gagtatggat
    52921 agtgtactta gaaattcaaa tgaaaagtat ataagtgctt ttaaagctgg agatgcagga
    52981 aatgaaaaat ctctaaacat actaaaggga agtgtaaaaa ctgttgataa taaggataaa
    53041 gatagacatc taaaaactac tattgattat aacattcaaa aaaaattaga acaaatacta
    53101 aataaagaag aaaatcctac agcagcaata atctcggaag catctacagg tgaaattctt
    53161 gcaatgtgct ctagacctaa ttttgaccaa aatgacatat caaaaagttt aaaaggaaaa
    53221 aatggagaat ttgaaaatag agttataaaa gcgacatatc caccagggtc tgtatttaag
    53281 atggtagttt tattttctgc acttgaaaat ggtgttatag atgagaacta tacttacaac
    53341 tgtacaggta agactaaagt tgggaatact aatgaaatac tgcgatgtaa taaaagagat
    53401 ggtcatggtt tccaaaactt aagacaagct ttttctaatt catgcaatcc tgcattttta
    53461 gatatagcta tgaaacttgg aaaagaaaag atactcaaat ctgctgaaaa attacattta
    53521 tttgaaaagg ttgatattgg tcttgatgaa gaaaaaatta gagaagctcc aaaaaacata
    53581 tcaataagaa atttagctat aggtcaagaa aatatagaat ttacaccact tcaaataaat
    53641 caaatgactc aaataatagc taataatgga acattcaaac cactatactt atataaaagt
    53701 cttgtggaca ataatatgaa tacaataaaa acttataagt cttcaaaaaa agaagaactt
    53761 atttctcctt atgtgtgtac acaagttaaa gaatatatga agtctgtatc taggactggt
    53821 acagctaaag acctaaaaga tattgaaggt ggttgtggag ttaaaactgg tacagctcaa
    53881 agtagtttaa ataaaaaagc tatagaccac ggatggataa caggatttta tcctgaagaa
    53941 agacctaagt atgtaataac tgtgttagta gaaggaactc aaaaaggaaa taaatctgca
    54001 acacctatat ttaaggaaat atgtgaaagt ataaaataaa ttatgtacta taaaatttaa
    54061 ggatatatcg taactttgat tttagataga aaattttgtc taatgatgta cgatatatcc
    54121 ttttaaaata tagtattaac tttcttgaac aagctctttt tctagttttt taagagcttt
    54181 tttttcgatt ctagatacat atgaccttga tatatcgagt ttttgtgcaa tttctctttg
    54241 tgtcttatag ccataaggag ttaacccata tcttaactgg acaatttctc tttctctagg
    54301 agtaagaatt ttgtttagtt gttcgtaaag ttttccaact tgaactttta gttcaacttc
    54361 atcaagaaca tagttagcct ctgtaccaag tatatctaaa agacttattt cattacacac
    54421 tactctttat atgttattga tattactagt cttcatgtaa tttcaaatga accattaatt
    54481 caaaagaatc tagtttttgt tctttagact tataataaac tgctttatca attacagatt
    54541 ttaggagttt attttttcca agtgaatctg aatcatggta aagtgataac acagttttaa
    54601 tatcttctat tattttagca ttgtcttttt taacagtact caatctattt tttactgtct
    54661 taattgaatc tttaatttct tcagttcttg aacttatatt gttggacctt tcaataaatg
    54721 tatcttcatc atatattcct cgttctagta aatcatataa cttatttttt tgcttgccta
    54781 attcttttaa ttcagtttct aagcccttta agactcgctt ttgaaattct atattactat
    54841 ctttattatt tttatctaag tctaaatcag atgcttttaa ttgatatttt tttacagtgt
    54901 cttccaaaga tttcaaaatg gcagcttcaa taaattcaaa tcgagaactt ttattgcaac
    54961 caggatgata acaaattata tagtcatggt ctgcatatgg tctatatact aatggtctac
    55021 cacaattttt gcaaatcact attcctgcaa gtggattttt tatttgatta ccatagctga
    55081 catgaccatt ttttttaagt atattttgag cctttttcca tgttatttca cttattaaag
    55141 gttcatgttt tccttttgct tcaatccatt catctttagg tcttagttta actgttttta
    55201 ttttatttgg atttttagat tttttatagt cctttttttg ccactgaata tatccacaat
    55261 aaactttgtt ttttattata tttgtaattg cagaattgta ccaattagca cctgtagcag
    55321 ttttaatgcc caagttattt aggtattttg atattttact acaacccata tcttcattaa
    55381 tatataagtc aaagatagtc ctaactacat cagcatcctt atttggtaca agtattcttt
    55441 cttttctacc agttgttaca gcatcatatc caaatggagc agaggttcct atgaaattcc
    55501 cttcttcaac tgattttatt cttcctcttt gcattcttct tgatataagt tttaattctt
    55561 ttcttgccat aaatgcttca aattctgaat actcctcatc aaattcatct gttaggtcgt
    55621 atgtttttct aggtgtgata attttggtct tactttcttt gaatgtttct aatatgatac
    55681 cttggtcttt catgtctcca cgaccaagtc tgtctaagtc cattactaag actgcatcat
    55741 atttattttc ttcaacttct tttagaagtt caagcatttt gggtctatgt attatacttt
    55801 caccagaaac taattcttct tttatctcaa ttacatctaa gttttgttct tttgctagtt
    55861 ttagtaaggt tgatttatgt ctacttaaag tttcaaattc gccttgtttt tctgcctctt
    55921 catcagcacg ggattttctt aagtatatgg caacactcat aataagtaat cacactcctt
    55981 aggtactatt atatattata atttagagtt ttaataatat ttttatatgt acttatttta
    56041 attataatag aatttaaaca agtgttttta attatataat ttaccataat atgatataat
    56101 aattgtagca agaagattta acttacaatc tatagagtgg agttcgtgta caaaagatta
    56161 tcctcccaac gattcgaagg gaggtgagtt catggataac tttttgttta atgttttagc
    56221 tagtttaaca gctagtgtag tagtttactt aatcagtaaa ctattcaaaa aagcaaaaag
    56281 ccactctcgc acaaagagtg acttacgagt tgaatttaaa tttatattta aatccaaaaa
    56341 ataaactctg tttatgatga actccactct aacgcaaaat agattgtagt tcttcttgct
    56401 tttattatat cacaaattag tacagatatt caaaaataat attttttttg atataataaa
    56461 aatgtagaga ttttgcagtg agcgatattt ttgataaaat agggcttaac agttgagata
    56521 tgaggcattg agggtatgtg ataaatctta tcaattgcac tactcatggt tcactgcaaa
    56581 tttgagagag ttgtatatgt gtagatattg aaaatactta gtttattttg gggttttata
    56641 ttaactaagt ggtatgtaaa gaatacatca ttaggagtac actcaagagc taggcaaagt
    56701 tttatattaa ctaagtggta tgtaaagtca tctcttgcaa caacttaact tcatcatctt
    56761 taagcgtttt atattaacta agtggtatgt aaagaatgat atatcaggag tagtatatat
    56821 tgtaatggat tcagaaggag cgtgggaatt taagattgca aaggaaatgg aagagtctga
    56881 atatcagata gacttaaata aaatcttata aaataaataa aatagagtgg tccatgacta
    56941 ctctatttta tttttagtgt ttatatatta tttatctctt tttttcaact cttcatctat
    57001 aaaatgacaa gctaataata gcggactgat ttctaagcca attgacaaat caactatagt
    57061 tggtattgta atatttttgt atttgtttct ttctaaatca gatatatact ctcgactata
    57121 gttagttcta tttgctaatt ctttttgtgt taaacctctt aaaatcctta aatcttttaa
    57181 catgcctgtt tcctcctaaa gtattataga taatctattt tttacatata gaaaaaaaca
    57241 atgcggttaa tagcaacatt ttttttgtgg aaatttgtgg tagaatgtag ttaagaatat
    57301 taagaaaatt tattttggag gtctataaat accgaccaaa taatttgtaa attatatgta
    57361 aaaataatgc aaaaaattgt aagaaaaaaa tcaaaaataa agtaatttat ttaagtgatt
    57421 ccgataaact gaaaagaaat tctcataaac caaaaataaa ttctgataaa tcgaaataaa
    57481 tgttatgatt tcttaaaatt aaaactaaaa tctcaaaagt aagcaagttg caagataata
    57541 ttaaaaaata tataattaat ttacaaagta attttaagaa aattagtgaa aatatattgg
    57601 tgtaaaaaag tgtatattag taaaataaat tgtaaataaa ataacaatat ctatattgga
    57661 aaaaagtttt aaa
//
LOCUS       DAYAOO010000015        56573 bp    DNA     linear   BCT 12-OCT-2024
DEFINITION  TPA_asm: Clostridioides difficile isolate ST8-SSI-h139-18
            SAMN40601845-rid21577343.denovo.015, whole genome shotgun sequence.
ACCESSION   DAYAOO010000015 DAYAOO010000000
VERSION     DAYAOO010000015.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN40601845
            Sequence Read Archive: SRR28438827
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 56573)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 56573)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-MAY-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-MAY-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002157583.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002157583.1
            Genome Coverage       :: 163x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/11/2024 16:19:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 4,038
            CDSs (total)                      :: 3,963
            Genes (coding)                    :: 3,930
            CDSs (with protein)               :: 3,930
            Genes (RNA)                       :: 75
            rRNAs                             :: 6, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 60
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 33
            CDSs (without protein)            :: 33
            Pseudo Genes (ambiguous residues) :: 0 of 33
            Pseudo Genes (frameshifted)       :: 7 of 33
            Pseudo Genes (incomplete)         :: 25 of 33
            Pseudo Genes (internal stop)      :: 11 of 33
            Pseudo Genes (multiple problems)  :: 8 of 33
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..56573
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN40601845-rid21577343.denovo.015"
                     /isolate="ST8-SSI-h139-18"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Denmark"
                     /collection_date="2018"
                     /collected_by="Statens Serum Institute"
     gene            302..1282
                     /locus_tag="ACGI5H_001049"
     CDS             302..1282
                     /locus_tag="ACGI5H_001049"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895229.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II CAAX endopeptidase family protein"
                     /protein_id="HFG9696773.1"
                     /translation="MNLKLIWINILNPVFIKNEIKRKKIQIIIFFFINFGLTYSLGLL
                     LYYNKFIDPENFASFMMILPLSSVAIAKFYTEGLNNDMYEFYSLIILFFLIYSLLIVL
                     KLLNLINNNEFIIINLILTFISSLSIIIYSSNKKNLYPVKNIKLGSLLIIYFMISVIV
                     PTSFILILQGAQPNYSGIIKFIFTPITSLTTIYIFFSEEYAWRGFLQNIFFDKFGKKL
                     GVIILGMCWSLWHLPLIFTLYTPEAPILGIILRSIHIVGISIFLGYLYIKTKNIWFCA
                     IIHVLNNSAFLITNSKESTITYHDILIVSMVVLIFYVPFLFTKEYKNNLE"
     gene            complement(1381..2343)
                     /locus_tag="ACGI5H_001050"
     CDS             complement(1381..2343)
                     /locus_tag="ACGI5H_001050"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018112760.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lysostaphin resistance A-like protein"
                     /protein_id="HFG9696774.1"
                     /translation="MNKSWSNLIIKNKDKKVRSGWIIIAVMATFYILQYYLSMILVEI
                     IRKILVATGDINLKTNYFSEYANWLNDVGLQIVFQILTDSLMIIIPIIVWRFIMKNPI
                     SEMGLHSYRIKKKEGYVGMLLGIFNCTVIFIITITIGGGHVTSWVPKISPLTVSWILV
                     FILVAFAEEILNRGFFMAVLRRCKNIYFIMIVPSVIFGLIHIWNPDVTFLSVINIIII
                     GILFSYMFIKSSNIWMCIGYHFAWNVFQGIIYGMPVSGLQVPGIITTQITHGNLLNGG
                     MFGIEGGILTTFVNLLSFIFVWYYYRDSKYDFVSDKVNVTNIKN"
     gene            complement(2659..3609)
                     /gene="hpdA"
                     /locus_tag="ACGI5H_001051"
     CDS             complement(2659..3609)
                     /gene="hpdA"
                     /locus_tag="ACGI5H_001051"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895227.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003824 - catalytic activity [Evidence
                     IEA];
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA];
                     GO_function: GO:0051536 - iron-sulfur cluster binding
                     [Evidence IEA];
                     GO_function: GO:0051539 - 4 iron, 4 sulfur cluster binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="4-hydroxyphenylacetate decarboxylase activase"
                     /protein_id="HFG9696775.1"
                     /translation="MSSQKQLEGMIFDVQSFSVHDGPGCRTTVFLNGCPLSCKWCANP
                     ESWTVRPHMMFSELSCQYENGCTVCHGKCKNGALSFNLDNKPVIDWNICKDCESFECV
                     NSCYYNAFKLCAKPYTVDELVQVIKRDSNNWRSNGGVTFSGGEPLLQHEFLHEVLLKC
                     HEVNIHTAIETSACVSNEVFNKIFNDIDFAFIDIKHMDREKHKEQTGVYNDLILENIS
                     NLANSDWNGRLVLRVPVISGFNDSVENISDIISFMHKNNLVEINLLPFHRLGESKWIQ
                     LGKEYEYSDKGDVDEGHLEELQDIFLDNGIACYVGHETAF"
     gene            complement(3602..3859)
                     /gene="hpdC"
                     /locus_tag="ACGI5H_001052"
     CDS             complement(3602..3859)
                     /gene="hpdC"
                     /locus_tag="ACGI5H_001052"
                     /EC_number="4.1.1.83"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420806.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-hydroxyphenylacetate decarboxylase small
                     subunit"
                     /protein_id="HFG9696776.1"
                     /translation="MRKHSDCMNFCAVDATKGICRLSKQMINLDDAACPEIKVMPKCK
                     NCKNFVEANDEGIGKCVGLEKEDWVYSTLNAITCEGHVFNE"
     gene            complement(3863..6571)
                     /gene="hpdB"
                     /locus_tag="ACGI5H_001053"
     CDS             complement(3863..6571)
                     /gene="hpdB"
                     /locus_tag="ACGI5H_001053"
                     /EC_number="4.1.1.83"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729211.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003824 - catalytic activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="4-hydroxyphenylacetate decarboxylase large
                     subunit"
                     /protein_id="HFG9696777.1"
                     /translation="MSQSKEDKIRSILEAKNIKSNFQNKENLSEFNEKKASKRAEDLL
                     DVYYNTLSTADMEFPYWYNREYRKSDGDIPVVRRAKALKAAFSHMTPNIIPGEKIVMQ
                     KTRHYRGSFPMPWVSESFFVAQGEQMREEAKKLASNTADELTKFGSGGGNVTESFGNV
                     VSIAGKFGMRKEEVPVLVKMAKEWVGKSVEDLGFHYEKMMPDYDLKENLMSTLICMFD
                     SGYTLPQGREVINYFYPLNYGLDGIIEMAKECKKAVAGNASGDGLIGMDRLYFYEAVI
                     QVIEGLQTWILNYAKHAKYLESIETDLEAKKEYSDLVEILEHIAHKQPRTFREALQLT
                     YTIHIASVNEDAISGMSIGRFGQILYPWYEQDIEKGLITKEEVIELLELYRIKITCID
                     CFASAGVNGGVLSGNTFNTLSIGGLKEDGSTGANELEELLLEASMRCRTPQPSLTMLY
                     DEKLPEDFLMKAAECTKLGSGYPAWVNNSNGTTFMMKQFADEGMTVEEARAFALGGCL
                     ETSPGCWKQLTLNGKTYSIAGGAGQSAGSGVHFIANPKILELVLMNGKDYRMNIQVFE
                     PHNKPLDTYEEVIEVFKDYYKQAINVLERANNIELDIWRKFDTSIINSLLKPDCLDKG
                     QHIGNMGYRYNATLNVETCGTVTMVNSFAALKKLVYDDKAFTIEEMKDAILNNFGFKD
                     ALEVGNYSMADQVKVDKTGKYDAIYKACLDAPKYGNNDLYADNILKNYEVWLSKVCEE
                     AQSLYAKKMYPCQISVSTHGPQGAATLATPDGRLSGTTYSDGSVSAYAGTDKNGVYAL
                     FESATIWDQAVVQNSQMNLKLHPTTIKGQQGTKKLLDLTRSYLRKGGFHIQYNVVDSE
                     TLKDAQKNPDNYRQLMVRVAGFTQYWCELGKPIQDEVIARTEYEGV"
     gene            complement(6868..7884)
                     /gene="tsaD"
                     /locus_tag="ACGI5H_001054"
     CDS             complement(6868..7884)
                     /gene="tsaD"
                     /locus_tag="ACGI5H_001054"
                     /EC_number="2.3.1.234"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860650.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0002949 - tRNA threonylcarbamoyladenosine
                     modification [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (adenosine(37)-N6)-threonylcarbamoyltransferase complex
                     transferase subunit TsaD"
                     /protein_id="HFG9696778.1"
                     /translation="MSDIITLAIESSCDETAASVLKNGREVLSNIISTQIETHKKFGG
                     VVPEVASRKHVENIDIVVQEALDKANIGFNDIDHIAVTYGPGLVGALLVGLSYAKALA
                     YTLNIPLVGVNHIEGHLSANYIEHKDLKPPFITLIVSGGHTHLVEVKDYGKYEILGKT
                     RDDASGEAFDKISRAMNLGYPGGPIIDNLAKNGNKHAIEFPRAYLEEDSYDFSFSGLK
                     SSVLNYLNGKRMKNEEIVVEDVAASFQEAVVEVLSTKALKAVKDKGYNIITLSGGVAS
                     NSGLRAKITELAKDNGITVKYPPLILCTDNAAMIGCAGYYNFINGKTHDMSLNAVPNL
                     KINQ"
     gene            complement(7890..8366)
                     /gene="rimI"
                     /locus_tag="ACGI5H_001055"
     CDS             complement(7890..8366)
                     /gene="rimI"
                     /locus_tag="ACGI5H_001055"
                     /EC_number="2.3.1.266"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009887996.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008999 -
                     peptide-alanine-alpha-N-acetyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0036211 - protein modification process
                     [Evidence IEA];
                     GO_process: GO:0042254 - ribosome biogenesis [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribosomal protein S18-alanine
                     N-acetyltransferase"
                     /protein_id="HFG9696779.1"
                     /translation="MEDNTKLIVDDIKIEEMTTEDIDEVFEVEKNCFEDYWSKESFRK
                     ELSNEVARYIVAKLNGKIVGYVGIWLILDEGHINNVAVHSDYRGKKIGDKLIKGIVDL
                     CKDNNIASMTLEVRASNKIAQNLYRKYGFKMGGIRKEYYSDNKEDAIIMWNQLKEV"
     gene            complement(8356..9072)
                     /gene="tsaB"
                     /locus_tag="ACGI5H_001056"
     CDS             complement(8356..9072)
                     /gene="tsaB"
                     /locus_tag="ACGI5H_001056"
                     /EC_number="2.3.1.234"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860649.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0002949 - tRNA threonylcarbamoyladenosine
                     modification [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (adenosine(37)-N6)-threonylcarbamoyltransferase complex
                     dimerization subunit type 1 TsaB"
                     /protein_id="HFG9696780.1"
                     /translation="MKILGMDTSSMAASVAVVEDDNLICEFTVNNKKTHSQKLMPMIE
                     NMLSMSDLSIKDMDLLAVCIGPGSFTGLRIGMATVKAMAHVNNIPIIAVNSLESLANN
                     INFCDRKICCILDAQKNQVYSAKYKFENGEMIELDGVDVVEFDALVDEIVSTNEEFII
                     VGEAVYKYKDKLENIKNIKIPSPANNVSNAGSLCSLALNKYNKNIDVHTCYTINPMYI
                     RKSQAEVQYDEKMKRLNNGR"
     gene            complement(9072..9524)
                     /gene="tsaE"
                     /locus_tag="ACGI5H_001057"
     CDS             complement(9072..9524)
                     /gene="tsaE"
                     /locus_tag="ACGI5H_001057"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434423.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0002949 - tRNA threonylcarbamoyladenosine
                     modification [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (adenosine(37)-N6)-threonylcarbamoyltransferase complex
                     ATPase subunit type 1 TsaE"
                     /protein_id="HFG9696781.1"
                     /translation="MAKIYLENENKTREIGYKLGKLLKEGSVICLVGDLGAGKTTMTQ
                     SLADSLGIEDYITSPTFTIINEYEGKIPLYHFDVYRIGSSDEMYDIGYDEYVNSNGIC
                     IIEWANLIEDILPKEYLNIELRYKDEGREMILTPKGEFYKEIVEELIK"
     gene            complement(9663..10703)
                     /locus_tag="ACGI5H_001058"
     CDS             complement(9663..10703)
                     /locus_tag="ACGI5H_001058"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892574.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4116 domain-containing protein"
                     /protein_id="HFG9696782.1"
                     /translation="MHLSKKIKKLFLDDKGYYFNSNWKDIHIGIYDTKLGDSLKYITN
                     EYIENMERVKYDYRELKNIENQTDGMCILAIRQNYKALEYVKNQTEELCLEAIKYNYK
                     ALEYVKEQTEYLCLEAIKKDCNALKYVRNKTEGLIIKAISHSSNIDVVSILKALETQT
                     RRICLEAIKKDGRCLAYVREQSEELCIEAIKQNYKALKYVKNQTEKMCIESVRQNGMA
                     LQYVNKQTDKICIEAVKQDGRSIQFVNNKTEEICINAIRYLNKKYNIKDVLSYIDKYT
                     EDICIEIVRQNGKMLMYIKNQTEKMCIEAVKENYKSLKYVKEQSERICKEALKQNHKA
                     KEYVKIAIDDCI"
     gene            complement(11032..11637)
                     /locus_tag="ACGI5H_001059"
     CDS             complement(11032..11637)
                     /locus_tag="ACGI5H_001059"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425422.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HFG9696783.1"
                     /translation="MQNTAKRGNMISTRTLVVMSILSAISYLLMFIQAPIPGIFPDFL
                     KIDLSDIPAIFGGMSLGPLVGFGIVVVKNVLQAITATTTGGIGEFANILIGGSYVMIL
                     CYSYKRSGDLKGVLIGFVLGTISMTIIGSLVNYFVMLPLYGQLMGLDAIIGLGSAINP
                     QVHDLFTFVIWMIAPFNVLKAVIISLVTLPLYKKMGNIIKK"
     regulatory      complement(11762..11879)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00050"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="FMN riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="flavin mononucleotide"
                     /db_xref="RFAM:RF00050"
     gene            complement(11939..13105)
                     /locus_tag="ACGI5H_001060"
     CDS             complement(11939..13105)
                     /locus_tag="ACGI5H_001060"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860647.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidohydrolase"
                     /protein_id="HFG9696784.1"
                     /translation="MIFIKNGKINTITNGIIHGDILIDEGKIIEIGEDLIAPLDVEVI
                     DASNKLVFPGFIDAHTHLGLWEDGIGFEGADGNEETDPITPQLNPIDGINPMDRTFKE
                     AFEGGITSVCTTPGSANVMGGQCIAIKTCGKRIDKMVIKNPVASKIAFGENPKSCYGQ
                     DDKSPQTRMAIAALLRENLKKAEEYLEDIDMYESHDDEDCEKPEYDIKMESLIPVLRR
                     EIPFKAHAHRADDMFTAIRIAKEFNLKLTLDHCTEGHLIVDELVEEGFPVIVGPSLSE
                     RSKFELRNLTFNTAGILSNAGLDVCIMTDHPVIPVQYLPICAGIAVKHGMKEEKAIES
                     ITINPAKALGIEDRVGSIEVGKDADLVIWDNSPLEIQSNVLYTIINGKVVYEKK"
     gene            complement(13253..15394)
                     /locus_tag="ACGI5H_001061"
     CDS             complement(13253..15394)
                     /locus_tag="ACGI5H_001061"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009887990.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005829 - cytosol [Evidence IEA];
                     GO_function: GO:0003676 - nucleic acid binding [Evidence
                     IEA];
                     GO_function: GO:0003729 - mRNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Tex family protein"
                     /protein_id="HFG9696785.1"
                     /translation="MDINQILKKEFNLRDEQINNTLKLIDEGNTIPFIARYRKEMTGE
                     MSDVTLREFYEKLMYLRNLQSRKDDVVRLIDEQGKLTDEITQNIEKAKTLQEVEDIYA
                     PYKQKKRTRATIAKEKGLENLALSILENNLDNIEIEAKNYLDEEKEVLSIEDALKGAR
                     DIIAELVSDDAKIRKYIRELALREGMIVSKSATDEKSVYDMYYDYSEAVKSMAPHRVL
                     AINRGEKESFLKVKLEINNDKVLNYIINEYVNDKNFKNKEEIVSSIEDSYKRLIFPSI
                     EREIRNHLTEIAQERAISVFGKNVKSLLLQPPVKDKVVMGFDPAFRTGCKIAVVDKNG
                     KLLDYTTVYPTDPQNDVEGAKKVLKGLIEKYDIDIISIGNGTASRESETFVSEMIKEI
                     DSEVQYVIVSEAGASVYSASELANEEHPDINVSIRGAISIARRLQDPLAELVKIDPKS
                     IGVGQYQHDLNKKRLEEVLDGVVEDSVNSVGVDLNTASYSLLEHVAGISKAIAKNIIA
                     YREENGDFTSRAQLKKVKRLGPQAFTQCAGFMRILEGKNPLDNTGVHPESYDICKKMI
                     EIIGYSLDDVKNKNIGEIDEKIKEIGLRELSEKLEVGQVTLKDIIAEIKKPGRDPREE
                     GIKPILRTDVLKIEDIQEGMTLKGTIRNVVDFGAFVDIGIKNDGLVHKSEMSNSFVKD
                     PMSIVTVGDIVDVKVIGIDLNKKRVALSMKK"
     gene            complement(15538..16645)
                     /gene="prfB"
                     /locus_tag="ACGI5H_001062"
     CDS             complement(join(15538..16569,16571..16645))
                     /gene="prfB"
                     /locus_tag="ACGI5H_001062"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_153309863.1"
                     /ribosomal_slippage
                     /note="programmed frameshift; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0016149 - translation release factor
                     activity, codon specific [Evidence IEA];
                     GO_process: GO:0006415 - translational termination
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor 2"
                     /protein_id="HFG9696786.1"
                     /translation="MLKLQEYRHSMEQMASNLEELRVSLDIASLMKNIQINEEKMNQQ
                     DFWNDNEVAQRVLQENKSLKETLEEYESLKSLLEDIEVLIEIGLEEDDDSVERDIEKS
                     IESMEEKLSEMKIKTLLNGEYDKNNAILSINAGTGGLDAQDWAQMLLRMYIRWSESKG
                     YKVKLLDIISDPEAGIKTATILVEGTNAYGYLKSEKGVHRLVRISPFDPSGKRHTSFA
                     SIDVTPELDENIEVEINPSDLKIDTYRASGAGGQHVNTTDSAVRITHIPTGVVVQCQN
                     ERSQHLNKDRAMRLLMAKLIELKELEQKEKIEDIQGKYSQITWGSQIRSYVFQPYKLV
                     KDHRTNAEFGNVDSVMNGNIDLFINEYLKMNKIV"
     gene            complement(16660..19335)
                     /gene="secA"
                     /locus_tag="ACGI5H_001063"
     CDS             complement(16660..19335)
                     /gene="secA"
                     /locus_tag="ACGI5H_001063"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895216.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006605 - protein targeting [Evidence IEA];
                     GO_process: GO:0006886 - intracellular protein transport
                     [Evidence IEA];
                     GO_process: GO:0017038 - protein import [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecA"
                     /protein_id="HFG9696787.1"
                     /translation="MSFMDNLFNMADKKELKKFNKTVDIIDSLEPKFESMADSELKNM
                     TNIFKERLANGESIDDILPEAFAVVREVSKRVLGLRHYRVQMIGGIVLHQGRIAEMKT
                     GEGKTLVATAPVYLNALTGKGVHVVTVNDYLAKRDRDQMAKIYEFLGMSVGVIIHGQN
                     PKVRKEQYDCDITYGTNNEYGFDYLKDNMVIHKEQRVQRGLNYAIVDEVDSILIDEAR
                     TPLIISGPGDKSTHLYSDANTFVLTLKPDDYELEEKDKAVSLTASGIQKAEVYFNVDN
                     ITDISHTELYHHINQALRAHVIMKKDVDYVAKDGEIVIVDEFTGRLMFGRRYSEGLHQ
                     AIEAKEGLKIQRESKTLATVTFQNYFRMYKKLSGMTGTAKTEEEEFKAIYKMDVFQVP
                     TNKLMIREDLPDCVYKSEIGKFNAVAQEIIERHKVNQPILVGTVSIEKSELLSQILKK
                     KGIKHEVLNAKHHDKEAEIIAQAGRLGAVTIATNMAGRGTDIVLGGNPDFLTKREMRR
                     NGFKEEIVNRVDTPIEGIPVKGNEILFEAREEYEKLFEKFKQQTQEEQKQVVEAGGLA
                     IIGTERHESRRIDNQLRGRAGRQGDPGSSRFYIGLDDDLMRLFGSDRISGIVDKIGLE
                     EDMPIEHRILSKSIEGAQKKVEGKNFGIRKHVLQYDDVMNKQREIIYAERKRVLEGED
                     LQEQIQSMTHSIIEEAVTLYTQDKGFDEEGFKEHMYNLFLPKGSIEIPEIEKLNPVEI
                     TEKVYEIAMKIYTSKEEQVGYERMREVERVILLQAVDNHWIDHIDAMDQLRQGIGLRA
                     VGQQDPVIAYKMEGFDMFDEMNKHIKEDTVRYLFNITIETPVERKAVVDVENLSSPSD
                     GTLPTSKTVKKDEKVGRNDLCPCGSGKKYKNCCGR"
     gene            complement(19467..20018)
                     /gene="raiA"
                     /locus_tag="ACGI5H_001064"
     CDS             complement(19467..20018)
                     /gene="raiA"
                     /locus_tag="ACGI5H_001064"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009887979.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0045182 - translation regulator activity
                     [Evidence IEA];
                     GO_process: GO:0009386 - translational attenuation
                     [Evidence IEA];
                     GO_process: GO:0036211 - protein modification process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome-associated translation inhibitor RaiA"
                     /protein_id="HFG9696788.1"
                     /translation="MNIIISGKQIELTDAIKNKIETKLSKLDNYIHPDTDVKVTVSAR
                     KARQKIEVTIATVNGPIIRAEDMQENLYTAIDVVYDKLSKQLKKYKKRLQDKHKDNKS
                     IRFQDAEINLADEQENYGDENQELVIQRRKKFSVKPMSEEEAVLQMELIGHDFYMFKN
                     IDSDEIAVVYKRNNGGYGIIEHE"
     gene            complement(20571..21245)
                     /locus_tag="ACGI5H_001065"
     CDS             complement(20571..21245)
                     /locus_tag="ACGI5H_001065"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860645.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005507 - copper ion binding [Evidence
                     IEA];
                     GO_process: GO:0055070 - copper ion homeostasis [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="copper homeostasis protein CutC"
                     /protein_id="HFG9696789.1"
                     /translation="MLEIIGMSVEDAKIIEDCGADRIELVSALTEGGLTPSFGLIESV
                     VNSVKIPVNVMIRHHAKSFVYSKEDISIMQKDISVVKEIGANGVVFGVLDKNNSIDEK
                     NLNVLLKCCDNLDVTFHRAIDESNTIDSVKILKDYDKITNILTSGGKGSIVDNIQMIK
                     NMMLSSNHIKILLGGGLNFNNIEKIKELTKASNFHFGTAIRINNSPFEDIDRQKLKQL
                     VNIISR"
     gene            complement(21248..22300)
                     /locus_tag="ACGI5H_001066"
     CDS             complement(21248..22300)
                     /locus_tag="ACGI5H_001066"
                     /EC_number="3.4.13.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860644.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA];
                     GO_function: GO:0016805 - dipeptidase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Sapep family Mn(2+)-dependent dipeptidase"
                     /protein_id="HFG9696790.1"
                     /translation="MNIISNKIDELKEDLLSDIIDIVKIPSVKGESENGFPFGEKVGE
                     ALNKALEISEKLGFKVRNLDNYIGYAEHGDSDDYVCVIGHVDVVHEGDGWKHQPYKGE
                     ETNGRIYGRGVLDNKGPIMSALYGLYAIKELNLKLDKRVRIIFGTNEESGFEDIPYYL
                     EKEKAPIMGFTPDCKYPVVYGEKGMAKIRIKSKINYEEDVYLGFIENMSENVLVTYKE
                     LNIENSDTILDIKVKYDFSYKLKDVLDEIKASFPNSIDIEVISNFNPVYFDKESNLVK
                     KLQLAYERVTSLDGTPVTTNGGTYAKVMPNIVPFGPSFPGQKGIAHNPDEYMDIEDII
                     LNAKIFANAIYELAKE"
     gene            complement(22349..23308)
                     /locus_tag="ACGI5H_001067"
     CDS             complement(22349..23308)
                     /locus_tag="ACGI5H_001067"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003432491.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N(4)-(beta-N-acetylglucosaminyl)-L-asparaginase"
                     /protein_id="HFG9696791.1"
                     /translation="MWGMIATWRMALEGITEASEHLEKGMEAGDAVELAVRRVEDYPF
                     YKSVGYGGLPNENCEVELDAAFMDGNTLDIGAVAGIRDYSNPVSIARKLSYEKVNNFL
                     VGIGAEDYAHKNGFERKNMLTDRAKLHYKKRKKETLDKGLSPYAGHDTVGMISLDKTG
                     KMCAATSTSGLFMKKRGRIGDSALSGSGFYVDSSIGGATATGLGEDLMKGCISYEIVR
                     LMKEGKHPQEACDIAVNELDKQLIKRRGKAGDLSLVAMNNKGEWGVATNIADFTFSVV
                     TKEESPTVYISNRVDGKTIHKVISNEWMEAYEARIKAPIEVSE"
     gene            complement(23401..23922)
                     /locus_tag="ACGI5H_001068"
     CDS             complement(23401..23922)
                     /locus_tag="ACGI5H_001068"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009901599.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GrdB-related putative oxidoreductase"
                     /protein_id="HFG9696792.1"
                     /translation="MKKIVMILDQIQAGAGGKEKSNIPPAGKSSPLGPGVMMEQFLNE
                     SKVIATLFCGDEFFVNNQEEVTSKMIAMVKKLNPDVVICGPSFNYENFSKMSAILSKN
                     INDKTDIPAFAAMSEENIDVINEYKNDICIVKTPKKGGIGLNDSLNNICKLAKAIANK
                     EDITLMKEEFCYQ"
     gene            complement(23933..25267)
                     /gene="celB"
                     /locus_tag="ACGI5H_001069"
     CDS             complement(23933..25267)
                     /gene="celB"
                     /locus_tag="ACGI5H_001069"
                     /EC_number="2.7.1.205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009901597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_function: GO:0019191 - cellobiose transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS cellobiose transporter subunit IIC"
                     /protein_id="HFG9696793.1"
                     /translation="MNRLERILMPLAEKIGKNKLLIAIRDGFLVSSPLLIIGSLFLLV
                     ANFPIKGWNEFVGQIFGPDWAVKLQQPTVATFEVMTLLAVLGIGYSYAKQIDVDPIAS
                     AAVAIVAFFIITPFVIPYTPEGTESVYMVTGIPLGWMGSKGMFVGMITAITSVKLFAA
                     VVKKGWTLKMPDGVPPTVSKSFAALIPSAIVMVVFFLVKIAFEATPYGSIHEFIFKFL
                     QMPLLKLGNSLGAMAIAYIFLHLFWFFGINGSSVVGAVYNPILKILSAENLAAFQAGS
                     KIPNIITGQFQDMFATFGGAGSTLSLVIAMLLICKSKRIKSMGKLSILPGIFGINEPL
                     IFGLPIMLNPILLIPFAIVPTINIIIAYFCMSAGLVPLTNGVQLPWTTPIIFSGFLTT
                     GWQGAVLQLVLLILGIFMYIPFIKMLDKQYLREENETVEEEDDDISFDDLVL"
     gene            complement(25306..25632)
                     /locus_tag="ACGI5H_001070"
     CDS             complement(25306..25632)
                     /locus_tag="ACGI5H_001070"
                     /EC_number="2.7.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425440.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HFG9696794.1"
                     /translation="MKRKVYLFCSFGMSTSLLADKMQKVADEHNLPIEVEAFPIAEID
                     KIVEEKNPDCILLGPQVKYMLKELKPKFEAQGKLIDIINEVDYGTMNGEKVLKLAIKL
                     IKSKQA"
     gene            complement(25656..25964)
                     /locus_tag="ACGI5H_001071"
     CDS             complement(25656..25964)
                     /locus_tag="ACGI5H_001071"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420747.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose/cellobiose transporter subunit IIA"
                     /protein_id="HFG9696795.1"
                     /translation="MEEIVLKIIIHAGNAKSMLYEALDYAKENDFKKADELIENANEE
                     ILKAHKVQTELIQKEAGGDKSDISILLIHSQDHLMTCMSERNLIKEMIMLRKEIQKLK
                     "
     gene            complement(26105..28018)
                     /locus_tag="ACGI5H_001072"
     CDS             complement(26105..28018)
                     /locus_tag="ACGI5H_001072"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HFG9696796.1"
                     /translation="MICLNKRQENLLTTLLLKEEFINVNKIANDFECSERTIRNDCKY
                     IDEWLSTFCNAYIKRKPNIGIKFSGDGTDKILVNQKLRGEVKRVNSELHKQVEILNLL
                     LCNNKKVTLNDLSNKLYINKNIVREEISKLSVALNNYNLNISTKKGSGIYIEGDEKDI
                     RIMLVSFLFKYIDKYRLNIDEIEYFHIVDIIIVKNIMLTIEEDMDIRLTDISFKQLML
                     FLLINIIRIRLGNSLKVSNTKKELKLKMLILDIEDELKSNLSIVLNYEEKLFIESLIL
                     GMNKQINSNNIKKSLYLNEELASYTKKIINLVSEESGINFNNDILLYEQLICHLNVTM
                     HQMKSNVYLENPLLDNIKTKFCFLFTVISSSIEIELKGKQITEDEIGYLTLHFQTSLE
                     RKYSKRESNKKASIVCPFSFGVSMLLKVKIEKRFDNIKIIETLREEDLKRDNFNKTID
                     FIIAFQEYENIQKPIFITTPLFTDEDENKLKEFTNKIKEKDTSYKLMNRLMMSDYLIR
                     ELEHDDIYEAITYLTNLLIEKHYAEKEYLQSIITREKSYPTNVGKGILFPHGDMKYIK
                     QSVLCFARLKTPIKIRNGKDIKIILLLAYKKDDDRKVFRELFKEISNLTEDENMLDIL
                     SKCDIEKVKDILI"
     gene            complement(28350..29090)
                     /locus_tag="ACGI5H_001073"
     CDS             complement(28350..29090)
                     /locus_tag="ACGI5H_001073"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434403.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ComF family protein"
                     /protein_id="HFG9696797.1"
                     /translation="MINKCLDFIYPENISCIICDKSIKKTNTYSICKSCFKEMNFIQD
                     GCMKCGKPIIRHSIEKEFIEECSYCFNKDFYFDKSISCIEYNDVTKKMVLGLKYNQKT
                     FMAKYIAQIMKEKLYLENIKFDYILFVPLHKKRLNKRGFNQAQKIAFNLSKIVNIPLL
                     DCISRKKYTRMLYKLNKKERKEELKNVFVVKENVKLINNKNILLIDDIFTTGLTTNEI
                     SKLLKLSGANKVFVLTLLTKANDNYIME"
     gene            complement(29135..31354)
                     /locus_tag="ACGI5H_001074"
     CDS             complement(29135..31354)
                     /locus_tag="ACGI5H_001074"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425443.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0043139 - 5'-3' DNA helicase activity
                     [Evidence IEA];
                     GO_process: GO:0032508 - DNA duplex unwinding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent RecD-like DNA helicase"
                     /protein_id="HFG9696798.1"
                     /translation="MEKLEGMISEIVFKNEDNGYTIAHLVNENDEIVVVGCMPTLAIG
                     ESIEVEGKWVNHKIYGTQFEVNSFMPVTPSSLEGIYVYLSSGMIHGIGEKMAKRIIDK
                     FGVDTLEVIQNSPEKLQEVEGIGSKKVKQIVKSYEEDRELRNIIIQLSPFGITPNYCL
                     KIYKKYKSSAIEVINKNPYQLAEDIRGIGFKVADSIASKIGIDKNSKDRICQGILYTL
                     NKSLSNGHTYLPEHVLIQDSEKLLELNGEIIKECVMMLVYNQKIHIEKVNNENLIYLM
                     PYYLAENGVCSQIVKLSQYEFEDLKIDIDNEINVLEEDKKIKLAEKQILAVKESVNSG
                     VLIITGGPGTGKTTTINAIIDIFENNGKSVTLAAPTGRAAKRMSETSNKEAKTIHRLL
                     EMGFSTDDDLTFFKDEEDPINSDVIIVDEVSMVDIILMYNLLRAIKLGTRVILVGDSD
                     QLPSVGAGNVLKDMINSNIINVVKLNEIFRQAQESMIIVNAHKINNGEPLYLNTKGKD
                     FFFIRKSTNEEILNEIIGLVNERLPKFYKVDKLKDIQVLSSMRKGELGVTNLNIELQK
                     YLNKKEKFKVEENFSKRLFRVGDKVMQVKNNYTKKWETEDQKESGEGIYNGDIGYVYH
                     IDKDKKTIYILFDQTKIVSYLYDELDEIDHSFCTTIHKSQGSEFPVVVLPIAWAPPML
                     LSRNLLYTAVTRAKKLVVLVGDVKYLEYMIKNNRVNQRYSNLGYKLNKFKQEGLLIE"
     gene            complement(31618..32715)
                     /locus_tag="ACGI5H_001075"
     CDS             complement(31618..32715)
                     /locus_tag="ACGI5H_001075"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003432466.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9696799.1"
                     /translation="MSGKVNIKTVISFAGAYVATVIGSGFATGQEILQFFTFYGYAGI
                     IGGIISMVLFSWFGAEVIDKGRELKLKEPIKIYQVYCGKYLGTFFEWFGPLFLFGTLV
                     IMIAGAGATLSEYYGLNPYVGRIGMAIVSLITVSLGLTRLSKILGNIGPIIIIFTLLV
                     GAISLFSNIDALSNAGNMVDSLNIKTATSNGYFSGVLYTCYNVIIVITFLTGMGASAV
                     NKKDAVWGGIVGGVALMAAAIMMNLALLSDIGNIYTKEIPALYLADKISPIIGILFSV
                     VLLLGIYTTAVPLLWSVTNRFVEDDHPKFKIITIVVSILACIGGLLPFDKLVGTLYPY
                     TGYMGILILLCMLYRRITKTEGYKENKSEIS"
     gene            complement(33030..34223)
                     /gene="metK"
                     /locus_tag="ACGI5H_001076"
     CDS             complement(33030..34223)
                     /gene="metK"
                     /locus_tag="ACGI5H_001076"
                     /EC_number="2.5.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003432462.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004478 - methionine adenosyltransferase
                     activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006556 - S-adenosylmethionine biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="methionine adenosyltransferase"
                     /protein_id="HFG9696800.1"
                     /translation="MARHLFTSESVTEGHPDKICDQISDSILDALLEKDPQSRVACET
                     TVTTGLVLVAGEISTSAYVDIPKLVRETVREIGYTRAKYGFDCDTCAVITSIDEQSGD
                     IAMGVDEGLESKTGEEIEEEIEKVGAGDQGIMFGFACNETPELMPLPISLAHKLSRRL
                     TEVRKTGLVDYLRPDGKTQVTVEYEGSKAVRVHTVLISAQHCETVSNDKIREDLINHV
                     IKEVIPAELLDEETKIYINPTGRFVIGGPQGDTGLTGRKIIIDTYGGYSRHGGGAFSG
                     KDPTKVDRSAAYAARYVAKNIVAAGLADKCEIELAYAIGIARPLSIFIDTFGTGKVSE
                     EKLVELVNKHFDLRPGAIIRDLDLRKPLYKKVAAYGHFGRTDIDLPWERTDKVEQLRK
                     DALGE"
     regulatory      complement(34360..34463)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00162"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="SAM riboswitch class I; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="S-adenosylmethionine"
                     /db_xref="RFAM:RF00162"
     gene            34652..35161
                     /gene="yyaC"
                     /locus_tag="ACGI5H_001077"
     CDS             34652..35161
                     /gene="yyaC"
                     /locus_tag="ACGI5H_001077"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009887970.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="spore protease YyaC"
                     /protein_id="HFG9696801.1"
                     /translation="MYLAKVNYSDDDVIQMLSSVLKTIINENTIVVCIGTDRAIGDTL
                     GPLVGTILKNSNFKYPVYGTLDNPIHALNIYESLDTIKNTHIQGNFLAIDACLGSQSN
                     IGNIQIREGPILPGKGVGKKLPQIGNYSIVGIVDKIDENNKLSFNNIRLSFILDLAET
                     IALALLVST"
     gene            complement(35272..35700)
                     /gene="fabZ"
                     /locus_tag="ACGI5H_001078"
     CDS             complement(35272..35700)
                     /gene="fabZ"
                     /locus_tag="ACGI5H_001078"
                     /EC_number="4.2.1.59"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425446.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-hydroxyacyl-ACP dehydratase FabZ"
                     /protein_id="HFG9696802.1"
                     /translation="MLNIDEIKKLIPHRYPFLLVDKITELEVGKRAVGIKNITVNEPF
                     FQGHFPEYPLMPGVLIVEALAQVCGVAMMSVEENKGKLGVFAGIDKVRIKREVRPGDT
                     LTMEVEMTTLRKNIAKADAKAYVGEELVCKGELMFALVEK"
     gene            complement(35716..36735)
                     /locus_tag="ACGI5H_001079"
     CDS             complement(35716..36735)
                     /locus_tag="ACGI5H_001079"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009901591.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rod shape-determining protein"
                     /protein_id="HFG9696803.1"
                     /translation="MAGADIGIDLGTANVLVYVSGKGIVLEEPSVVAIDKRTDSVLAV
                     GEEAKKMIGRTPGNIVAIRPLRDGVISDYDVTEKMLKSFIDKIVDKKGFGRFFMPRIM
                     VCVPTGVTEVEKRAVEDATRQAGAREVYIIEEPIAAAIGAGVDISQPNGNMIIDIGGG
                     TVDIAVISLGGAVVSESIKVGGDRFDDAIVKYMKKQHNLLIGERTAEKIKFEIGSAFK
                     REEEKYMKITGRNLITGLPSSITINSTEMLEALRECVEQIVVATHAVLEKTPPELAAD
                     IGDVGIIMTGGGSLLYGLDKIIEQRTGITVTIADEPLSCVAKGTGIALGSIDLLETGG
                     SFKRK"
     gene            complement(36932..37192)
                     /gene="spoIIID"
                     /locus_tag="ACGI5H_001080"
     CDS             complement(36932..37192)
                     /gene="spoIIID"
                     /locus_tag="ACGI5H_001080"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420727.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0140110 - transcription regulator activity
                     [Evidence IEA];
                     GO_process: GO:0030436 - asexual sporulation [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sporulation transcriptional regulator SpoIIID"
                     /protein_id="HFG9696804.1"
                     /translation="MRSHIEERAIVVAKYILEKNTTVRQTAKTFGVSKSTIHKDVTER
                     LKEINPSLAKEVKNVLDKNKSERHIRGGLATKLKYEKEHKKM"
     gene            complement(37290..37958)
                     /locus_tag="ACGI5H_001081"
     CDS             complement(37290..37958)
                     /locus_tag="ACGI5H_001081"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420724.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidoglycan DD-metalloendopeptidase family
                     protein"
                     /protein_id="HFG9696805.1"
                     /translation="MKKKLLEKDGFYLSLFVCVCLLAVGGVWFTNNNVDKLASNKGIM
                     ENANKDSEEEIHLIEKDKKDAIPTATDSKQNLEKAKSKEENKSSTTKLNYIGDKVIRG
                     YSEKEPSYSKTLDVWETHKGVDISCTKGKEVKSLLNGIVVDVFDDEEYGQSVKIKSDN
                     NIVVVYSNLDKNVSVKKEQKVTEGQSLGTVGSTSQIESEEGIHVHLEAYSGEKSIDPM
                     SLIK"
     gene            complement(38024..39088)
                     /gene="spoIID"
                     /locus_tag="ACGI5H_001082"
     CDS             complement(38024..39088)
                     /gene="spoIID"
                     /locus_tag="ACGI5H_001082"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009887965.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0030436 - asexual sporulation [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="stage II sporulation protein D"
                     /protein_id="HFG9696806.1"
                     /translation="MKNPLVVLLGFVTCSVLVPSLITLVSYKNVELTEKPESPVSINK
                     TIKKSDIEDKGNKEEKNTVNYETVNKKAPIINVYNHITGKTEKMDMENYLCGVLAGEM
                     SSEFDIEALKAQSVAARTYVVYKQEHGKSSKHKNAVVCTDYKHCQEYKSYDTLKKLNG
                     EEWIKNKYSKIQEAVRGTKGQIITYNDKAILPLYFSTSSGKTENSEEVFSAKYPYLKS
                     VESPYDKYSPKFASTLKISNTDFVKSLRRAYSTIVIDVNNLSKQVSITKRSDAGTVEK
                     IKLGNKELTGKDIRTVFKLNSANFDIKFGEGYIDFVVKGYGHGVGMSQWGAEGMAEEG
                     YKYYDILSHYYTDTKIKDIY"
     gene            complement(39175..40428)
                     /gene="murA"
                     /locus_tag="ACGI5H_001083"
     CDS             complement(39175..40428)
                     /gene="murA"
                     /locus_tag="ACGI5H_001083"
                     /EC_number="2.5.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420721.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008760 - UDP-N-acetylglucosamine
                     1-carboxyvinyltransferase activity [Evidence IEA];
                     GO_process: GO:0019277 - UDP-N-acetylgalactosamine
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylglucosamine
                     1-carboxyvinyltransferase"
                     /protein_id="HFG9696807.1"
                     /translation="MAKIIVKKSNPLKGSVKIDGAKNAVLPIIAATLLANGKSTLNGV
                     PNLRDVHVISDLLRHVGAEVEYKENTLTVDASNIKTCEAPYELVRKMRASFLVMGPLL
                     ARFNSTKISMPGGCAIGTRPIDLHLKGFKALGAKIEMDHGFVEAATEKLVGNKLYLDF
                     PSVGATENIMMAASLAEGTTIIENAAEEPEIVDLANFLNEMGADVKGAGTNTIKIKGV
                     KELKGAEHNVIPDRIEAATYMVAAAMTKGDITVENVLMEHLKPVVAKLREAGCEITEM
                     DNSVRVVGPKVLKPIDIKTLPHPGFPTDVQAQFMAMLTVANGTGVVIETVFENRFMHV
                     AEFNRMGANIKIDGRSAVVNGVDELHGAAVNATDLRAGAALILCGLIAEGETQIGEIY
                     HIQRGYVDIDKKITALGGQIEIVED"
     gene            complement(40449..41186)
                     /locus_tag="ACGI5H_001084"
     CDS             complement(40449..41186)
                     /locus_tag="ACGI5H_001084"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003432450.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YwmB family TATA-box binding protein"
                     /protein_id="HFG9696808.1"
                     /translation="MKKVKLAISFFILMIIGMTISYADTSINTRYNRLSKALEISEAN
                     FKFYNVKINSVINHNLSNKEFHNIFIEIINNLKLDKKGINWNQKGSGDKIQLCATIKG
                     SDKEISIKGINKNNKESYIVVDILDNKVYKHKEVIYSNVENVLNKYSSQVDVSACIVG
                     EYTKRLQNNKYDDILQKILYNMSAKQIDEVKDVNFLSITAYSKVLNDYELEYLGEKIN
                     LNIGIKYNEDDGKTLIYIATPIIKLDY"
     gene            complement(41642..42937)
                     /locus_tag="ACGI5H_001085"
     CDS             complement(41642..42937)
                     /locus_tag="ACGI5H_001085"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860639.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhodanese-like domain-containing protein"
                     /protein_id="HFG9696809.1"
                     /translation="MTNDFKKEKKEDYFVNLKAISTEVLQEKVQDNAWVIVDTRLNDA
                     YNGWKLDGVKRGGHIKGAVDFSANWLSVYSDRKDEVLEQALKTKRIDLDKNIVLYDAN
                     GKDALVVADYLSKKGYKYLYKYDIKQWADDENLPMERYKNYQMIVPAFIIKDILDGKI
                     PETFEDSKNIKMIEASWREESYTKGHIPTSVHVNTDIIEPPPTWMLDNDDNLTKFALD
                     YGLTKDDTVIVSSSTPMASYRLAVILRYIGVKDVRVLNGGTNSWLSAGYELEFISNPK
                     HSCTNFGADIPVNSQLIVTTSELRQKLKEKNKFILVDNRTWDEHIGKVSGYTYYDKKG
                     RIPGALYGHSGSDSVSLEEYRNIDNTMRNKYEILEMWDKENIDVNKQLIFMCGSGWRA
                     AEVLTYANVIGVENTSLYSDGWMGWSLDNSNLIEVGEHK"
     gene            complement(43388..45220)
                     /gene="glmS"
                     /locus_tag="ACGI5H_001086"
     CDS             complement(43388..45220)
                     /gene="glmS"
                     /locus_tag="ACGI5H_001086"
                     /EC_number="2.6.1.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892563.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004360 - glutamine-fructose-6-phosphate
                     transaminase (isomerizing) activity [Evidence IEA];
                     GO_process: GO:1901137 - carbohydrate derivative
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine--fructose-6-phosphate transaminase
                     (isomerizing)"
                     /protein_id="HFG9696810.1"
                     /translation="MCGIVGYLGSRKAAEVIVEGLSKLEYRGYDSAGVAVNSSNEKEL
                     NIRKFKGRLSVLAEDLEKNPIDGNLGIGHTRWATHGEPSDVNSHPHFNQAKTIAVVHN
                     GIIENYMEIKEELISEGVKFESQTDTEVIAHLVDKYYEGNLLDAVYKTISKLRGAYAL
                     GVICKEHGNELVAVRKDSPLVVGVGEGENFIASDIPALLKYTRDVYFLENGEVVHLKD
                     ENVTVYDSNRNLVEKEVFHVTWDVEAASKGGYDYFMSKEIHEQPTGVRETLERRLDDN
                     GNIILDSINISKEDLEKINKVYIVACGTAYNAGLLGKYAIEKFVNIPVITDIASEFRY
                     SDPFVDENSLVILVSQSGETADTLAVLRDSKAKGARILSITNVVGSSIARESDDVFYT
                     WAGPEVAVASTKAYTTQITSLYMIALDFAIKKGTITREFYDSMISKMKEIPSKIQEIL
                     DNEEYIKEVAKTVVSSEHAFYLGRGIDYSLAMEGSLKLKEISYIHAEAFAAGELKHGT
                     IALIEKGTPVIAIATQEKLFEKMVSNMEEVRARGAYVVAIAQSHNKDVEKAADKIIYI
                     PNSDDILSPILAVVPMQLLAYHVSVLRGCDVDKPRNLAKSVTVE"
     gene            complement(45487..46833)
                     /gene="glmM"
                     /locus_tag="ACGI5H_001087"
     CDS             complement(45487..46833)
                     /gene="glmM"
                     /locus_tag="ACGI5H_001087"
                     /EC_number="5.4.2.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860638.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000287 - magnesium ion binding [Evidence
                     IEA];
                     GO_function: GO:0008966 - phosphoglucosamine mutase
                     activity [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA];
                     GO_process: GO:0009252 - peptidoglycan biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoglucosamine mutase"
                     /protein_id="HFG9696811.1"
                     /translation="MRKYFGTDGVRGVANTELTCDLAYKLGRAGGFVLAQGDHRVKVV
                     VGKDTRISGDMLEASLIAGLMSVGCDVITVGIIPTPAVAYLTRKYGADCGVVISASHN
                     PVEYNGIKFFNKNGYKLDDEIELKIEEYIDDIDKIDCLPIGENVGRKLHEHCAQRDYV
                     DYLKSIISTDFKGLKVVLDCANGASYKVAPIVFDELGASVISINSSPDGNNINYKCGS
                     THPEQLQRAVLEHNADLGLAYDGDADRLIAVNEKGQIVDGDHIMILSALNLKKNNKLA
                     QDTLVVTVMSNIGLTIAAKENGINLSTTAVGDRYVLEDMVKNGYNLGGEQSGHMIFLD
                     YNTTGDGVLSSLILANIILQEKKPLSEIASIMSQYPQVLVNATIKNENKNKYMEYPEI
                     KTEIERIESILDGNGRVLIRPSGTEPLVRVMLEGKEEGQIKELATNLANLIQEKLS"
     gene            complement(47003..47560)
                     /locus_tag="ACGI5H_001088"
     CDS             complement(47003..47560)
                     /locus_tag="ACGI5H_001088"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420711.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016903 - oxidoreductase activity, acting
                     on the aldehyde or oxo group of donors [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="2-oxoacid:acceptor oxidoreductase family
                     protein"
                     /protein_id="HFG9696812.1"
                     /translation="MSTARVICAGFGGQGVMSMGQLLTYAGMLEGKEVSWLPSYGPEM
                     RGGTANCAVTVSNEPVGSPLITDDATAAILLNIPAFEKFKDDVIPGGKIIVNSSLIKE
                     KVDRTDVDVYYIPANELAAELGNDKVANMIMLGAYLKVSDTVDIESVLEAFKKVFGPR
                     KEKFVPLNREALQKGMDATCSKATN"
     gene            complement(47561..48313)
                     /locus_tag="ACGI5H_001089"
     CDS             complement(47561..48313)
                     /locus_tag="ACGI5H_001089"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420710.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003824 - catalytic activity [Evidence
                     IEA];
                     GO_function: GO:0030976 - thiamine pyrophosphate binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="thiamine pyrophosphate-dependent enzyme"
                     /protein_id="HFG9696813.1"
                     /translation="MAVVFKKTEGLQDTQTHYCPGCTHGIIHRLVGEVLEELGVLGDA
                     VGVVPVGCSVLGYKYFNCDTQEAAHGRAPAAATGIKRVHPENTVFTYQGDGDLASIGT
                     AEIVHAAARGEKITTIFVNNTTYGMTGGQMAPTTLVGQRATTAQSGRNAETQGYPIRV
                     SEMLATLTGAVFVERVAVDTPAHVRQAKKAIKKAFQVQQAGLGFGIVEVLSTCPTNWG
                     LAPNDALQWLRDNMIPYYPLGNFKNVEVEEVK"
     gene            complement(48313..49392)
                     /locus_tag="ACGI5H_001090"
     CDS             complement(48313..49392)
                     /locus_tag="ACGI5H_001090"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420707.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-methyl-2-oxobutanoate dehydrogenase subunit
                     VorB"
                     /protein_id="HFG9696814.1"
                     /translation="MAKILMKGNEAFGKAAIEAGCKYFFGYPITPQSELPEYLSRELP
                     KIGGAFVQAESEVSAINMVYGGAGAGARVMTSSSSPGVALKQEGITYAVGAEVPCVVL
                     NVMRGGPGLGSIQPSQADYFMSTRGGGNGDYRTPVFAPATVQEAVDMIMEAFDVADYY
                     RSPVMVVADGMIGQMMEPVEFRAPEKKRELPPKDWATVGTKGKRKPNVINSLYLEPEV
                     LEDHCWHLQEKFDAMEKNEVQYEMYKTEDAEFVFAAYGTTSRVVKSAIDILREEGIKA
                     GLIRPKVLWPFPFEAFNQIPNARNILTVEMSMGQMVEDVKMAVEGKLPVYFHGRPGGM
                     TPTPAEIVEKAKKIIAGELVAGGAR"
     gene            complement(49421..49636)
                     /locus_tag="ACGI5H_001091"
     CDS             complement(49421..49636)
                     /locus_tag="ACGI5H_001091"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420706.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4Fe-4S binding protein"
                     /protein_id="HFG9696815.1"
                     /translation="MAKGKVSFNQERCKGCGLCVEACPVKIIQLDSNVINKKGYNPAT
                     VFEMEKCIGCASCATMCPDVVITVERD"
     gene            complement(49679..50356)
                     /locus_tag="ACGI5H_001092"
     CDS             complement(49679..50356)
                     /locus_tag="ACGI5H_001092"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425471.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HFG9696816.1"
                     /translation="MITNDKRIRIITGHYGSGKSEFAMNYVVKLRDMVSGKVAIADLD
                     VVNVYFRTREKKELMKSLGIQPIDSSINAPTLDLPAVSAEVMSPMVDHSYNSVIDLGG
                     DNVGARVIGRFSHLLKEGDYDMLFVINANREKTQTSEEVIQYIKEIEKSSKLKVTGLI
                     NNTHLIRFTTIDDVLRGQKVAKEVSEKCNIPIRYVACLENLVEQLPKDLEGEIFPIKL
                     YMREDWM"
     gene            complement(50346..51425)
                     /gene="buk"
                     /locus_tag="ACGI5H_001093"
     CDS             complement(50346..51425)
                     /gene="buk"
                     /locus_tag="ACGI5H_001093"
                     /EC_number="2.7.2.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420702.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0047761 - butyrate kinase activity
                     [Evidence IEA];
                     GO_process: GO:0006113 - fermentation [Evidence IEA];
                     GO_process: GO:0016310 - phosphorylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="butyrate kinase"
                     /protein_id="HFG9696817.1"
                     /translation="MSKIFKILTINPGSTSTKIAVFDNEDLVFEKTLRHSSEEIGKYE
                     KVSDQFEFRKQVIEEALKEGGVKTSELDAVVGRGGLLKPIKGGTYSVSAAMIEDLKVG
                     VLGEHASNLGGIIAKQIGEEVNVPSYIVDPVVVDELEDVARISGMPEISRASVVHALN
                     QKAIARRYAREINKKYEDINLIVAHMGGGVSVGAHKNGKIVDVANALDGEGPFSPERS
                     GGLPVGALVKMCFSGKYTQDEIKKKIKGNGGLVAYLNTNDAREVEERIEAGDEKAKLA
                     YEAMAYQISKEIGASAAVLKGDVKAILLTGGIAYSKMFTEMIADRVKFIADVKVYPGE
                     DEMIALAQGGLRVLTGEEEAQVYDN"
     gene            complement(51447..52349)
                     /gene="ptb"
                     /locus_tag="ACGI5H_001094"
     CDS             complement(51447..52349)
                     /gene="ptb"
                     /locus_tag="ACGI5H_001094"
                     /EC_number="2.3.1.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425473.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0050182 - phosphate butyryltransferase
                     activity [Evidence IEA];
                     GO_process: GO:0019605 - butyrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate butyryltransferase"
                     /protein_id="HFG9696818.1"
                     /translation="MRSFEEVIKFAKERGPKTISVACCQDKEVLMAVEMARKEKIANA
                     ILVGDIEKTKEIAKSIDMDIENYELIDIKDLAEASLKSVELVSQGKADMVMKGLVDTS
                     IILKAVLNKEVGLRTGNVLSHVAVFDVEGYDRLFFVTDAAMNLAPDTNTKKQIIENAC
                     TVAHSLDISEPKVAAICAKEKVNPKMKDTVEAKELEEMYERGEIKGCMVGGPFAIDNA
                     VSLEAAKHKGINHPVAGRADILLAPDIEGGNILYKALVFFSKSKNAGVIVGAKAPIIL
                     TSRADSEETKLNSIALGVLMAAKA"
     gene            complement(52653..53834)
                     /locus_tag="ACGI5H_001095"
     CDS             complement(52653..53834)
                     /locus_tag="ACGI5H_001095"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420699.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CdaR family protein"
                     /protein_id="HFG9696819.1"
                     /translation="MINRLKNNTKIKIISFLSAIALWMYVMAVVDPEETKGFEDIPVS
                     ISNMSDLKDKNLVIYPDEKLTADVYIKGSLSKVQSVKKEDIHVYGTIEDPIQGQKEVY
                     LKANIPQGVTLEFKHDVLVVNLEKNIKEKRDIKVEVSGNSKRNINKIELSKEFVDVSG
                     PRTLVKEVKSVRANLDVGNETDDFSKKLQLIPLNSDGTKVEGVTLSSSFVTAKIELLK
                     EKIVPIRVSLNDNKDNDVLKNYKLSKEQVTIKGKKEDIDKISYIKTKPIDLADLANGE
                     EKEVSLEIPEGITLEDSSITIKLNDTKQLSAEFLYNAGDIELRNIPTNMDNPNVISDV
                     DIKVVVESMEDLSKLNKKDISLYIDLSQGPEEDSKYKIKYETTYQFKKINIEPNIVEV
                     E"
     gene            complement(53831..54670)
                     /gene="cdaA"
                     /locus_tag="ACGI5H_001096"
     CDS             complement(53831..54670)
                     /gene="cdaA"
                     /locus_tag="ACGI5H_001096"
                     /EC_number="2.7.7.85"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420697.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004016 - adenylate cyclase activity
                     [Evidence IEA];
                     GO_process: GO:0006171 - cAMP biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="diadenylate cyclase CdaA"
                     /protein_id="HFG9696820.1"
                     /translation="MLDINSFLNGFFNIILRMSIYDLIDISIVAYIFYKIFMFIKDTR
                     AEQVFKGIIFLLLATQLSNTFKLHTVYWISLKALDYGVIAALIIFQPEFRAGLEHIGR
                     AKFNLFGKNVNTSEETLNRNIEEIVEALYSLSRQKIGALIIMERETRISDIINTGTII
                     DAEISRQLLINIFIPNTPLHDGAVVIRDSKVKAAACFLPLTESKDLSKDLGTRHRAGI
                     GVSEVSDCITLIVSEETGGVSIAKAGKLYRDISRERMMNILRSNLKTNTETRSFFKGG
                     IFK"
     gene            complement(55654..55727)
                     /locus_tag="ACGI5H_001097"
     tRNA            complement(55654..55727)
                     /locus_tag="ACGI5H_001097"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(55691..55693),aa:Arg,seq:tct)
     gene            complement(55737..55811)
                     /locus_tag="ACGI5H_001098"
     tRNA            complement(55737..55811)
                     /locus_tag="ACGI5H_001098"
                     /product="tRNA-Gly"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(55777..55779),aa:Gly,seq:gcc)
     gene            complement(55822..55898)
                     /locus_tag="ACGI5H_001099"
     tRNA            complement(55822..55898)
                     /locus_tag="ACGI5H_001099"
                     /product="tRNA-Asp"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(55862..55864),aa:Asp,seq:gtc)
     gene            complement(55904..55979)
                     /locus_tag="ACGI5H_001100"
     tRNA            complement(55904..55979)
                     /locus_tag="ACGI5H_001100"
                     /product="tRNA-Val"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(55944..55946),aa:Val,seq:tac)
     gene            complement(55985..56058)
                     /locus_tag="ACGI5H_001101"
     tRNA            complement(55985..56058)
                     /locus_tag="ACGI5H_001101"
                     /product="tRNA-Gly"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(56024..56026),aa:Gly,seq:tcc)
     gene            complement(56073..56147)
                     /locus_tag="ACGI5H_001102"
     tRNA            complement(56073..56147)
                     /locus_tag="ACGI5H_001102"
                     /product="tRNA-Glu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(56112..56114),aa:Glu,seq:ttc)
     gene            complement(56155..56230)
                     /locus_tag="ACGI5H_001103"
     tRNA            complement(56155..56230)
                     /locus_tag="ACGI5H_001103"
                     /product="tRNA-Met"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(56195..56197),aa:Met,seq:cat)
     gene            complement(56246..56331)
                     /locus_tag="ACGI5H_001104"
     tRNA            complement(56246..56331)
                     /locus_tag="ACGI5H_001104"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(56295..56297),aa:Leu,seq:taa)
     gene            complement(56337..56411)
                     /locus_tag="ACGI5H_001105"
     tRNA            complement(56337..56411)
                     /locus_tag="ACGI5H_001105"
                     /product="tRNA-Asn"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(56377..56379),aa:Asn,seq:gtt)
     gene            complement(56419..56535)
                     /gene="rrf"
                     /locus_tag="ACGI5H_001106"
     rRNA            complement(56419..56535)
                     /gene="rrf"
                     /locus_tag="ACGI5H_001106"
                     /product="5S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00001"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00001"
BASE COUNT        17095 a        10693 c         6102 g        22683 t
ORIGIN      
        1 cttcattaat tttatcaact atgcctctac tgcctattaa tttaatgcaa taaataataa
       61 atcttttaca aaaagataat aaaaatatag aaaaatattt tttattgtcc ttttggttat
      121 ggtaaaccac attctgcctg caatataact aaatatatgg gtagatagta aaattaattt
      181 tattatttat atataatttt ataagttact tttcaataat attgactgtc attaatttat
      241 aatattcaat aaaatatttt aatttagtta agaatctata ttgtaaagga gtattaaatt
      301 aatgaactta aaattaatat ggataaatat tctaaaccca gtatttatta aaaatgaaat
      361 aaaaagaaaa aaaatacaaa ttattatctt tttctttata aactttggtt taacttattc
      421 attaggttta ctgttatatt ataataaatt tattgatcca gaaaactttg catcattcat
      481 gatgatatta cctctatctt cagttgccat tgcaaagttt tatactgaag gattaaataa
      541 tgatatgtat gaattttatt cactaatcat attatttttt cttatttatt cattattaat
      601 tgttcttaag ttattaaatc taataaataa taatgaattt ataattataa acctaatatt
      661 aacttttata agtagcttat caattataat atattcatca aataaaaaaa atttatatcc
      721 tgtaaaaaat attaaactag gttctttatt aattatttac tttatgattt ctgtaattgt
      781 tccaacatca tttatactaa tactacaagg ggctcaacct aattatagtg gtatcataaa
      841 atttatattt actccaataa catcattaac tactatttat atttttttta gtgaagaata
      901 tgcctggaga ggttttttac agaatatttt ttttgataaa tttggtaaaa agttaggagt
      961 tataatatta ggtatgtgtt ggagcttgtg gcacttacca ctaatattta cattatatac
     1021 acctgaagcg ccaatattag gaataatatt acgttcaata catatagttg gaatttcaat
     1081 atttttagga tatctttata taaaaactaa gaatatctgg ttttgtgcta taattcatgt
     1141 tttaaataat agtgcttttc ttatcacaaa ttctaaagaa tcaactatca cttaccatga
     1201 tatactaata gtatctatgg ttgttttaat tttttatgtt ccatttctat ttacaaaaga
     1261 atataaaaat aacttggagt aaatagaata tccaagttat ttttatattt ttgcaaattt
     1321 ccaacaatcc tacagaatac tttaagctta gaagatatta ttaaaattta ttataatcaa
     1381 ctaattcttg atattggtca catttacttt atcactaaca aaatcatact tagaatctct
     1441 atagtaatac catacaaata taaagctaag tagattaaca aaagtagtca aaattccacc
     1501 ttcaatacca aacattcctc catttaatag attaccatga gtgatttgtg tagttataat
     1561 ccctggaact tgaagtccac ttacaggcat accatatata atcccctgaa atacattcca
     1621 tgcaaaatga taacctatac acatccatat attcgacgat tttataaaca tatatgaaaa
     1681 aagaatccca ataattataa tattaattac agacaaaaaa gtaacatcag gattccatat
     1741 atgaatcaac ccaaaaataa cagatggaac aatcattata aaataaatat ttttacatct
     1801 tcgtaaaact gccataaaaa aaccacgatt taaaatttct tctgcaaaag caactaaaat
     1861 aaagaccagt atccaagaaa ctgttaaagg tgaaattttt ggtacccatg aagtaacatg
     1921 accaccacca attgttattg ttataataaa gattactgta caattaaata ttcctaataa
     1981 cattcctaca tatccttctt ttttcttaat tctataagaa tgtaatccca tttcactaat
     2041 aggatttttc ataataaatc tccatacaat tataggaata ataatcataa gtgaatctgt
     2101 tagaatttga aatacaatct gtaacccaac atcatttaac caattagcat attctgaaaa
     2161 atagtttgtt tttaaattaa tgtcacctgt agcaaccagg atttttctta ttatttccac
     2221 aagtatcatg cttaaataat actgaagtat gtaaaaggta gccataacag ctataataat
     2281 ccaccctgaa cgtacttttt tgtctttatt cttaataatc aagttgctcc atgatttgtt
     2341 catatagatg tcttcctcct aactattatt tttagttgtt tctaaaatat attctattaa
     2401 attttttcat agtagtattt taccacaaaa cttctgcttc aatgaagtaa gcgtaatata
     2461 ttctctaact gtaatttaaa ctataaaaaa tatataaagt atatttaaag caatatttat
     2521 ggacataaag caatataaac aatatataaa acatataaaa ctttacttaa ttatttctac
     2581 ataaaaacca cataaaaaag gatgtaactc tagcttttag tgtaacatcc tttttttaat
     2641 taaaacttgt atttaatttt agaaagctgt ctcatgacca acataacaag ctataccatt
     2701 atccaaaaat atatcttgta attcttcaag atgaccttca tcaacatcac ccttatcaga
     2761 atactcatat tccttgccta attgaatcca ttttgattct cctaatctgt gaaatggtaa
     2821 tagattaatt tctaccaaat tatttttgtg cataaaagat ataatatcac ttatattttc
     2881 aacactatca ttaaacccag agataactgg tactctaagt actaatcttc cattccaatc
     2941 agaatttgca aggtttgata tattttctaa tattaaatca ttatacacac ctgtttgttc
     3001 tttgtgtttt tctctatcca tatgctttat atcaataaat gcaaaatcaa tatcgttaaa
     3061 tattttatta aaaacttcat ttgatacaca tgcactcgtt tcaatggcag tgtgtatatt
     3121 tacctcatga cactttaata atacttcatg taaaaattca tgctgaagta gtggctcacc
     3181 tccactaaat gttactcctc cattacttct ccaattgtta gaatcacgtt taattacctg
     3241 cacaagttca tctacagtgt aaggttttgc acataattta aacgcattat aataacatga
     3301 gttgacgcat tcaaaacttt cacagtcctt acagatgttc caatctataa ctggcttatt
     3361 atcaagatta aagctcaatg caccattttt acacttacca tgacatacag tacatccatt
     3421 ttcatattga caagataatt cactaaacat catatgtggt cttacagtcc aactttctgg
     3481 atttgcacac catttacaac tcagtggaca tccatttaaa aatacagttg ttctacaacc
     3541 tggaccatca tgaactgaaa agctttgtac atcaaaaatc atgccttcta attgcttttg
     3601 actactcatt aaacacatgt ccttcacaag taattgcatt caatgttgaa tatacccagt
     3661 cttctttctc taggccaaca catttgccta taccttcatc attagcttca acaaaatttt
     3721 tacaattttt acattttggc attactttta tctctggaca tgctgcatca tctaaattaa
     3781 tcatttgttt tgataatcta caaattcctt tggttgcatc tactgcacaa aaattcatac
     3841 aatcactatg ctttctcata ttttacaccc cttcatactc tgttctagca attacttcat
     3901 cttgtattgg tttacctaat tcacaccaat attgagtaaa cccagcaaca cgtaccatta
     3961 attgacgata attgtcagga tttttttgtg catcttttaa tgtttctgaa tctacaacat
     4021 tatattgaat atggaaccca ccttttctta aataacttct tgttaaatct aataattttt
     4081 tagttccttg ttgtcctttt atagtagttg gatgaagttt taaattcatc tgagaatttt
     4141 gaactactgc ttggtcccaa atagttgcag attcaaataa tgcatatact ccatttttat
     4201 ctgttcctgc atatgcagag actgaaccat ctgaatatgt tgttccactt agtctaccat
     4261 ctggagtagc caaggtagca gctccctgtg gcccatgtgt agaaacagat atttggcaag
     4321 ggtacatctt cttagcatat aaagattgtg cttcttcaca tacttttgat aaccatacct
     4381 catagttttt aagaatatta tctgcataca aatcattatt tccatattta ggtgcatcaa
     4441 gacaggcctt ataaatagca tcatatttac cagtcttatc tacttttact tggtctgcca
     4501 tagaataatt tcctacttct aatgcatctt taaatccaaa attatttaat atggcatcct
     4561 tcatttcctc tattgtaaat gctttgtcat catatacaag tttcttaagt gctgcaaatg
     4621 aattgaccat agtaacagta ccacaagttt ctacgtttaa tgttgcatta taacgatatc
     4681 ccatatttcc tatatgttga cctttgtcta aacagtctgg ctttagtagt gaatttatta
     4741 tagaagtatc aaattttctc catatatcta actcaatgtt atttgctctt tctaaaacat
     4801 ttattgcttg tttataataa tctttaaata cttctatgac ttcttcataa gtatctaatg
     4861 gcttattatg aggctcaaat acttgtatat tcatacgata gtctttacca ttcataagaa
     4921 caagttctaa aatttttgga ttagctataa agtgaactcc agagccagca gattgacctg
     4981 ctccacctgc aatagagtat gtttttccgt ttaaagttaa ctgtttccaa caccctggag
     5041 acgtttccaa acatccacct aatgcaaatg ctcttgcttc ttcaacagtc ataccttcat
     5101 cagcaaattg tttcatcata aatgttgttc catttgagtt gtttacccat gctggataac
     5161 cagaaccaag ctttgtacat tcagcagctt tcattaagaa atcttctgga agcttttcat
     5221 catatagcat agttaaacta ggttgaggag ttctacatct catacttgct tctaataata
     5281 actcttctag ttcattagct cctgtagaac catcttcttt taatccacct atagataaag
     5341 tattaaatgt attgcctgat agtactcctc catttacgcc cgctgaagca aaacagtcaa
     5401 tacaagtgat ttttattcta taaagctcta ataattcgat aacctcttct tttgtaatta
     5461 gtcctttttc tatatcttgt tcataccaag gatataaaat ttgaccaaaa cgtcctatag
     5521 acataccaga tatagcatcc tcatttactg atgctatatg aattgtataa gtcaactgaa
     5581 gagcttccct aaatgtacga ggttgtttat gtgcaatatg ttctaatatc tccactaaat
     5641 ctgagtattc ttttttagct tctaaatctg tctctatact ttctaaatat tttgcatgtt
     5701 ttgcataatt taaaatccaa gtttgtaatc cttcaataac ttgaataaca gcctcataaa
     5761 aatatagacg gtccatacca ataagcccat ctccagatgc atttcctgca actgcctttt
     5821 tacattcttt tgccatttct ataattccat ctaatccata atttaaagga taaaaataat
     5881 ttataacttc tctaccttga ggaagtgtat accctgaatc aaacatgcat ataagtgtac
     5941 tcattaggtt ttcttttaaa tcataatctg gcatcatttt ttcatagtga aaacctaaat
     6001 cttcaacaga ctttccaacc cattcctttg ccatttttac aagtacaggt acttcttctt
     6061 ttctcattcc gaatttacca gctattgaaa cgacatttcc aaaactttca gtaacatttc
     6121 ctccaccaga cccaaatttt gtaagttcat cagctgtgtt actggctaat ttctttgcct
     6181 cttctctcat ttgttctcct tgagcaacaa agaagctttc acttacccat ggcattggaa
     6241 aagaacctct ataatggcgt gtcttttgca ttactatttt ctcaccaggt attatatttg
     6301 gtgtcatatg tgaaaaagca gctttaagag ctttagctct tctaactact ggtatatcac
     6361 catctgattt tctatattct ctattatacc aatatggaaa ttccatatca gcagtagata
     6421 atgtattata atatacatct aataagtctt ctgctctttt acttgctttt ttttcattaa
     6481 attcacttaa attttcttta ttttgaaaat ttgatttaat attttttgct tccaaaatac
     6541 ttcttatttt gtcttcttta ctttgactca tttcttcccc tccttaatct ttctataatt
     6601 agtataaaac tttttaagaa tgaaaaaaaa gggtatatta cccacttttt aaaataatct
     6661 ttctatagaa aaaaataaac ttgaagcaaa tctaagccaa agacaatctg tatatcctaa
     6721 aatttgttgc aattcattgg aatataaaga ttataaatag ttttacttca agttttaata
     6781 tatactatat ttatttttat tatatttaat ttcacttcta cttacttttt tgaaacaata
     6841 cttttatatt tacaaattca tctaactcta ctgatttatc tttaaatttg gaactgcatt
     6901 taaactcata tcatgcgttt tcccatttat aaaattataa tatcctgcac accctatcat
     6961 agctgcatta tctgtgcata aaattagagg aggatactta acagtaatac cattgtcttt
     7021 agcaagctct gttattttag ctctaagccc cgaattagaa gcaaccccac cagaaagagt
     7081 tatgatattg tatcctttgt cttttactgc ttttagtgct ttagtagata aaacctctac
     7141 tacagcctct tggaaagatg ctgctacatc ttcaactact atttcttcat ttttcattct
     7201 ttttccattt agataattta atacagaaga ttttaatcca ctaaaactaa aatcatagct
     7261 atcttcttct aaataggctc ttggaaattc tatagcatgt ttatttccat tcttggccag
     7321 attatcaata ataggacctc ctggatagcc taaattcata gctcttgaaa tcttatcaaa
     7381 tgcttctcca gatgcatcat ctcttgtttt tcctaaaatt tcatacttgc cataatcttt
     7441 tacttcaacc aagtgagtat gacctccaga tactattaat gttataaaag gaggttttaa
     7501 atccttatgc tctatatagt ttgcacttag atgcccttct atatgattta ctcctacaag
     7561 tggaatattc aaagtatatg caagtgcttt agcataagat agaccaacca ataaagcacc
     7621 tactagccca ggtccatatg taactgcgat atggtctata tcattaaaac ctatatttgc
     7681 tttgtctaaa gcttcttgaa caactatatc aatattttcc acatgttttc ttgaggccac
     7741 ttctggaact acaccaccaa attttttatg tgtctcgatt tgagtagaga ttatgtttga
     7801 aagtacttct ctaccatttt ttaaaactga tgcagctgtt tcgtcacaac tactctctat
     7861 agctaatgtt attatatcac tcataaactc tacacctctt ttaattggtt ccacattata
     7921 attgcatctt ctttattatc actgtagtat tcttttctta ttccacccat tttaaatcca
     7981 tattttctat ataaattttg tgctatttta tttgatgctc taacttctaa tgtcatagat
     8041 gcaatattat tatctttaca taaatcaact atgcctttta tcaacttgtc ccctattttt
     8101 ttccctctat agtcactatg aacagccaca ttatttatat gcccttcatc aagtataagc
     8161 caaattccca catatccgac aatttttcca tttaacttag ctactatata ccttgctact
     8221 tcattagaca actcttttct aaaagactct tttgaccaat aatcttcaaa acaatttttt
     8281 tctacttcaa aaacttcatc tatatcttct gtagtcattt cttctatttt tatatcatct
     8341 actattagtt ttgtattatc ttccattatt tagcctcttc attttttcat catattgtac
     8401 ttcagcttga gattttctga tatacatagg atttatcgta taacaagtat gtacatctat
     8461 atttttatta tatttattta atgctaaaga gcataagctt cctgcgttag atacattatt
     8521 agctggtgaa ggtattttta tattttttat attctctaac ttgtctttat atttgtatac
     8581 agcttctcca actattataa attcttcatt agttgataca atttcatcta ctaaagcatc
     8641 aaactctaca acatcaacac catctaattc tatcatctct ccattttcaa acttgtattt
     8701 agctgaataa acttgatttt tctgtgcatc taatatacaa catatctttc tatcacagaa
     8761 atttatgtta tttgctagag attccaaaga atttactgct attattggta tattatttac
     8821 atgggccata gcttttactg tagccatacc tattctaagt cctgtaaacg aacctggacc
     8881 tatacataca gctaataaat ccatatcttt tatacttaaa tcactcatac tcaacatatt
     8941 ttctatcatt ggcataagct tttgtgaatg agtttttttg ttgtttactg taaactcaca
     9001 tattaagtta tcatcttcaa caactgctac acttgctgcc atagaagacg tatccatacc
     9061 tagtattttc attatttaat caactcctca actatctctt tataaaactc tccttttgga
     9121 gttaatatca tttctcttcc ttcatcttta tatctcaatt ctatattcaa atattctttt
     9181 ggaagtatat cttctattag attagcccat tctattatac agattccatt tgaatttaca
     9241 tattcatcat aaccaatatc atacatttca tcactactac ctattctata aacatcaaaa
     9301 tgatacaaag gtatttttcc ttcatattca tttattatag taaaagtagg acttgttata
     9361 taatcttcta tccctaatga atctgccaaa ctttgtgtca ttgtagtttt accagctcct
     9421 aaatctccta ctaaacagat aacactgcct tcttttaaaa gtttacctaa tttatatcct
     9481 atttctctag ttttattttc attttctaaa tatatttttg ccatcaattc atctccattt
     9541 tgatataatc gtcatgtgaa tttatatcac tgcttaatta attatagtat aagcctagat
     9601 tattataaag tacttgtctt tatctttttt tatctttcac tattgatggc tgtatctaca
     9661 ccttatatac aatcatcaat agcaattttt acatactctt ttgctttatg gttttgcttc
     9721 aatgcttctt tacatattct ctcagattgc tcttttacat acttaagaga cttatagttc
     9781 tcttttactg cttcaataca cattttttct gtttgatttt ttatatacat aagcattttt
     9841 ccattttgtc ttacaatctc tatacatata tcttctgtat acttatctat gtaacttagt
     9901 acatctttaa tattatattt tttatttaaa tatcttatag catttataca tatttcttct
     9961 gtcttattgt tgacaaattg tatacttctt ccatcttgtt tgacagcttc tatacatatt
    10021 ttatcagttt gtttatttac atattgtaat gccataccat tttgtcttac ggattctata
    10081 cacatttttt ccgtttgatt ttttacatat tttaatgctt tataattttg cttaatggcc
    10141 tctatacata attcttcact ctgttctcta acgtatgcaa gacacctgcc atctttttta
    10201 attgcttcta aacatatcct tcttgtttga gtctctaaag cctttagtat acttacaaca
    10261 tctatattgg aagaatgact tattgctttt ataataagcc cttctgtttt atttcgtaca
    10321 tacttaagtg cattacaatc tttttttata gcttcaagac acaagtattc tgtttgttct
    10381 tttacatatt caagtgcttt ataattatac tttattgctt ctaaacataa ttcttcggtt
    10441 tgatttttta catactctaa tgccttgtaa ttctgcctta ttgctaaaat acacatacca
    10501 tcagtttgat tttctatatt ttttaattca cgataatcgt attttaccct ttccatattt
    10561 tcaatatatt cattagtgat atactttaaa gaatctccta attttgtatc ataaatacca
    10621 atatgaatat ctttccaatt actattaaaa taataccctt tatcatctaa aaataatttt
    10681 tttatttttt tagataaatg catgaatata cacccctatc attattaaat tagttattat
    10741 taaaagtttg attattaatc tttatagttt tttaataata actttatttt ttgtttatta
    10801 taaattcgct ctgtatattg tagatacctt tttcatattt taatagttaa tcgttttaat
    10861 tcttccttta ttttaaaatt taaatttgtc taaatatttc ttattttata tacatttttt
    10921 gataaattaa taaagccata atatatttaa tatatcaatc acaatatagg actgaagtta
    10981 taaataaatt atggctattc aatacattta attttatatt ttcttgtcta attatttctt
    11041 tattatattt cccatttttt tataaagtgg caatgttact aaagatatta taacagcctt
    11101 cagcacatta aatggagcta tcatccaaat tacaaaagtg aataaatcat gaacttgagg
    11161 atttatagct gaacctaaac ctattatagc atctagtccc ataagttgac cataaagtgg
    11221 caacattaca aaataattta ctaatgaacc aattatagtc atagatattg ttcctaatac
    11281 aaaaccaatc agtacacctt ttaaatctcc acttctctta tatgaataac aaagtatcat
    11341 tacataagaa ccaccaatta atatatttgc aaattctcct attcctccag ttgttgttgc
    11401 tgttattgct tgtaacacat tttttactac aactattcca aatccaacta atggtcctag
    11461 agacattcct ccgaatattg ctggaatatc tgataagtca atttttaaga aatctggaaa
    11521 tatacctggt attggtgctt gaataaacat taataaataa gatattgcag ataaaattga
    11581 cattactact aaagttcttg ttgaaatcat attgcctctt tttgctgtgt tttgcataat
    11641 tattttcccc ctaatcaata tgtttatatt ttttaggaaa aacaaaaaac tcgaagaccc
    11701 tatcttcgag tttttatgga tatagtttaa acaaactaaa ataaacttat ttatcttcca
    11761 taaatatctt ctctcatcca gactttactg tcggctttgg aatctcacca aatcaaccac
    11821 ctaagtagtt cgcgggctat accgccggta gggaatttca ccctgccccg aagatcttct
    11881 ttgatttttt aattttcctt acactcttat attagttaat tttttaataa ttgtcaagtt
    11941 attttttctc atacactact ttgccattta ttatagtgta aagtacatta ctttgaatct
    12001 ctagtggaga attatcccaa attactaggt ctgcatcttt accaacttct atagagccta
    12061 ctctatcttc tattcctaaa gccttagctg gatttatcgt aattgattct attgcttttt
    12121 cttctttcat accatgtttt actgcaatac ctgcacatat tggaagatat tgaactggta
    12181 ttactggatg gtctgtcatt atacatacat caagacctgc atttgaaagt attcctgctg
    12241 tattaaatgt caaatttcta agctcaaatt tagacctttc tgacaaagat ggccctacta
    12301 ttacaggaaa cccttcttcc actaattcat ctacaataag atgaccttct gtacaatggt
    12361 ctaatgtaag ctttaaatta aattcttttg caattcttat tgctgtaaac atatcatctg
    12421 ctctatgagc atgtgcctta aaaggaattt ctcttcttaa aactggtatt aaactttcca
    12481 tttttatatc atattcaggt ttttcacagt cttcatcatc atgactctca tacatatcaa
    12541 tatcctctaa atattcttct gcttttttta ggttttctct aagtaaagca gctatagcca
    12601 ttctagtttg aggagattta tcatcctgac cataacagct ctttggattt tctccaaaag
    12661 caattttaga tgcaactgga ttttttatta ccattttatc aattcttttt ccacatgtct
    12721 ttatagctat acattgacca cccataacat ttgcacttcc aggggttgta caaacagaag
    12781 ttattccacc ttcaaaagct tctttaaaag ttctatccat tggattaatt ccatctatag
    12841 gatttaattg tggtgttatt gggtcagtct cttcatttcc atctgctcct tcaaacccta
    12901 taccatcttc ccataaacct aagtgagtat gagcatctat aaatccagga aacacaagtt
    12961 tattactagc atctattacc tctacatcta aaggagctat caaatcttct ccaatttcta
    13021 ttatttttcc ttcatctata agtatatctc catgaattat cccatttgtt atggtattta
    13081 ttttaccatt ttttataaaa atcattcatt ttcctcctga ttttcaagac tatcgttctt
    13141 attttaatat attttcttac tatatacttt tacaaatttt taacatttat acactcgagt
    13201 aatcttattt acaaatatag aatctaagta ctataaccat acataaactt atctattttt
    13261 tcattgataa ggcaactctt tttttgttta agtcaattcc aatgactttt acatctacta
    13321 tatcacctac tgtaacaata ctcatagggt ctttcacaaa actattactc atttctgatt
    13381 tatgaactaa tccgtcattt tttattccaa tatctacaaa tgcaccaaag tctacaacat
    13441 ttcttattgt accttttaaa gtcataccct cttgtatatc ttcaattttt aagacatcag
    13501 ttctaagtat aggttttata ccttcttctc ttgggtctct tcctggtttt ttgatttcag
    13561 ctatgatatc ttttaacgta acttgtccta cttccagttt ttcacttaat tccctcaagc
    13621 caatttcttt tattttttca tctatttcac ctatattctt attctttaca tcatctaaag
    13681 aatatccaat tatctcaatc atttttttac atatatcata actttcagga tgcacacctg
    13741 tattatctag tggattttta ccctctaaga ttctcataaa tccagcacat tgagtaaatg
    13801 cttgaggtcc tagtcttttt acttttttca attgtgctct tgacgtaaaa tctccatttt
    13861 cttctctata tgctattata ttttttgcta tagctttact tattcctgca acatgttcta
    13921 gtagggagta tgatgcagta tttaaatcta ctccaacact atttacagaa tcttcaacaa
    13981 ctccatctag tacttcttct aatctctttt tgtttaaatc atgctgatat tgaccaacac
    14041 caatactttt agggtctatt tttacaagct ctgctaatgg gtcttgtaat cttctagcta
    14101 tagatatagc tcctcttatt gatacattta tatctggatg ttcctcattt gcaagttcag
    14161 atgctgaata aacagatgct cctgcttcac taactatcac atactgcact tcgctatcta
    14221 tttcttttat catttctgat acaaaagttt ctgattctct agatgcagta ccatttccaa
    14281 ttgaaattat atctatatcg tatttttcaa tcaatccttt taaaactttc tttgctccct
    14341 ctacatcatt ttgagggtct gttggatata ctgttgtata atctagtagt ttaccatttt
    14401 tatctactac agctatttta catccagttc taaatgcagg gtcaaatccc ataactactt
    14461 tgtctttaac tggtggttga agcaataaac ttttaacatt ctttccaaat acacttatag
    14521 ctctttcttg agctatttct gttaaatgat ttcttatttc tctttctatt gatgggaaaa
    14581 ttaatctttt ataagaatct tctattgaac ttacgatttc ttctttattt ttgaaatttt
    14641 tatcatttac atattcgttt attatgtaat ttaaaacttt atcattattt atttccaact
    14701 taacctttag gaagctttct ttttctcctc tgtttattgc caaaactcta tgtggagcca
    14761 tactttttac tgcttcgcta taatcataat acatatcata aaccgatttc tcatcagtag
    14821 cacttttgct aactatcata ccttctctta aagctaattc tcttatatac tttctaatct
    14881 tagcatcatc tgagactagt tctgcaatta tatctctagc accttttaga gcatcttcaa
    14941 tagaaagaac ttctttctct tcatcaagat aattctttgc ctctatttct atattatcta
    15001 aattattctc tagtattgac aatgctaaat tttctaatcc tttttctttt gctattgttg
    15061 ctctagttct tttcttttgt ttatatggag catatatatc ttctacttct tgtaatgttt
    15121 ttgctttttc tatattttgt gttatttcat ctgttaattt cccttgttca tctattagtc
    15181 taactacatc atcttttcta ctttgaagat ttctcaaata cattaatttt tcataaaatt
    15241 ctcttagtgt aacatcactc atttcgccag tcatttcttt tctatatcta gctataaatg
    15301 gtattgtatt tccttcatca ataagtttta atgtattatt tatttgttca tctctaagat
    15361 taaactcttt ttttaagatt tgatttatat ccaatttatt cactcctaat gttagttttt
    15421 cataagtata acaaaacaga acgaaggctg agggttatcg tcctcagcct aagtgctgta
    15481 agtgcatatt aagcactaac cttcttatac atatatctta attacagtgc atatttatta
    15541 aactatttta ttcattttta agtattcatt aataaacaag tctatatttc cattcattac
    15601 actatctaca tttccaaact cagcatttgt tctatggtct ttaaccaatt tatatggttg
    15661 aaaaacatat gacctaattt gactacccca agttatttgt gagtatttgc cttgtatatc
    15721 ttctattttt tccttttgct ctaactcttt taattctatc aatttcgcca ttaaaagtct
    15781 catagctctg tccttattta gatgctgaga cctttcattt tggcactgaa ctactacacc
    15841 agtagggata tgtgttattc taactgctga atcagtcgta tttacatgtt gccctccagc
    15901 tccagaagct ctatatgtgt ctatctttaa atctgatgga ttaatttcta cttctatatt
    15961 ttcatctaac tctggtgtta catctataga tgcaaatgaa gtatgtcttt ttcctgatgg
    16021 gtcaaatgga gatattctca ctaatctatg aactcctttt tcactcttta aatacccata
    16081 agcatttgtt ccttctacaa gaattgtagc tgtctttatc cctgcttcag ggtctgatat
    16141 tatatctaaa agcttaactt tataaccctt actttctgac catcttatat acattctcaa
    16201 aagcatttga gcccaatctt gagcatctaa gccaccagta ccagcattta tagataatat
    16261 agcattattt ttatcatact ctccatttag aagagtcttt attttcattt cagataattt
    16321 ttcttccatt gattctatgg acttttctat atctctttct acagaatcat catcttcttc
    16381 taaacctatt tcaattaata cttctatatc ttctaataag ctttttaagc tttcatattc
    16441 ttctaatgtc tcttttaaag atttattttc ttgaagtact ctttgagcga cttcattatc
    16501 attccaaaaa tcttgttgat tcatcttttc ttcattaatt tgtatatttt tcatcaatga
    16561 agctatgtca aagagaaacc ctcaattctt ctaaatttga agccatctgc tccatactat
    16621 gtctatactc ttgtaacttt aacatttaat cctccgagat tatcttccac aacagttttt
    16681 atatttttta ccacttccac aagggcataa gtcatttctt ccaacctttt catctttttt
    16741 aacagtttta cttgttggaa gtgttccatc tgatggagaa gatagatttt caacatctac
    16801 aactgctttt ctttccactg gagtttctat tgttatatta aataaatatc ttacagtatc
    16861 ttctttgata tgtttattca tttcatcaaa catatcaaaa ccttccattt tataagcaat
    16921 aactgggtct tgctgaccta cagcacgaag accaatacct tggcgtaatt ggtccatagc
    16981 atctatatgg tctatccaat ggttatcaac agcttgaagt aagattactc tctcaacttc
    17041 tctcattctc tcatagccaa cttgttcttc ttttgaagta tatatcttca tagctatttc
    17101 ataaactttt tctgttattt caactggatt aagtttttct atttctggta tttctatgct
    17161 accttttggc aagaacagat tatacatatg ttctttgaat ccttcttcat caaatccttt
    17221 atcttgtgta taaagagtaa ctgcttcttc tattatagaa tgagtcattg attgtatttg
    17281 ttcttgtaaa tcttcacctt ctaatacacg ttttctctct gcatatatta tttctctttg
    17341 tttattcata acatcatcat attgaagtac atgctttctt attccaaagt ttttaccttc
    17401 gactttcttt tgtgctcctt caatagactt agataatatt ctatgttcta tcggcatgtc
    17461 ttcttcaaga cctattttat ctacaatacc agatattcta tcactaccaa acaatctcat
    17521 aaggtcatca tcaagaccta tatagaatct tgaactccct gggtcacctt gacgtccagc
    17581 acgacctctc aactggttat ctattcttcg agattcgtgt ctttctgtac ctattatagc
    17641 aagtccacct gcttctacaa cttgtttttg ttcttcttgt gtttgttgct taaacttttc
    17701 aaatagtttt tcatactctt ctctagcttc aaatagaatt tcattacctt ttacaggtat
    17761 accttctatt ggagtatcta ctctatttac tatttcttct ttaaatccat ttcttctcat
    17821 ttctctctta gttaaaaagt ctggatttcc acctagaact atatctgtac cacgaccagc
    17881 catattagta gctattgtaa cagctccaag tctaccagct tgtgctatta tttctgcctc
    17941 tttatcatga tgcttagcat ttaatacctc gtgctttatg ccctttttct ttagtatttg
    18001 tgataataat tctgattttt ctattgatac tgtacctaca agtattggtt gattgacttt
    18061 gtgcctttca attatttctt gtgctacagc attaaattta cctatttcac ttttgtatac
    18121 acagtctggt aagtcttccc ttatcataag cttattagta ggtacttgga aaacatccat
    18181 tttgtagatt gctttaaact cttcttcttc tgtttttgct gtaccagtca tcccagaaag
    18241 ttttttgtac attctaaagt aattttggaa tgttacagta gctagtgttt tagattctct
    18301 ttgtatttta agaccttctt tagcctctat tgcttgatgt aaaccttctg aatatcttct
    18361 accaaacata agtctacctg tgaactcatc tactattact atttctccat ctttagcaac
    18421 ataatcaaca tctttcttca ttattacatg tgctcttaaa gcttgattta tatgatggta
    18481 taattctgta tgagatatat ctgttatatt atcaacatta aaatacactt ctgctttttg
    18541 tatacccgat gctgttagag atacagcctt atctttttct tctaattcat aatcatctgg
    18601 ttttaaggtt aaaacaaatg tgtttgcatc tgaatataag tgagttgatt tgtctccagg
    18661 tccagatatg ataagtggtg ttctagcctc atctattagt atagagtcaa cctcatccac
    18721 tatagcataa tttaatcctc tttgaactct ttgctctttg tgtattacca tattgtcctt
    18781 tagatagtca aatccatatt cattatttgt accataagtt atatcacaat catattgttc
    18841 ttttctaact tttggatttt gaccgtgtat aataacgcct acactcattc ctaaaaactc
    18901 atagattttt gccatttggt ctctatcacg ttttgcaagg taatcattta ctgttacaac
    18961 atgtacacct tttccagtaa gcgcattcaa ataaacagga gcagttgcaa ccaaagtttt
    19021 accttcacct gttttcattt ctgctattct tccttgatgt agtactatac ctccaatcat
    19081 ttgaactctg tagtgtctaa gtcctaacac tctcttagaa acttctctaa ctactgcaaa
    19141 agcttctgga agtatatcat ctatactttc accatttgct aatctttctt taaatatatt
    19201 tgtcatattt ttaagttccg agtctgccat agattcaaat ttaggttcta atgaatctat
    19261 tatatcaaca gttttattga acttttttaa ttctttttta tctgccatgt tgaataaatt
    19321 atccataaag ctcatatttt acatctctcc tcgttcttta ttgtactatt attcatttta
    19381 ccataaaaac tatactttta atattaattt aaaaagctat cgataattta tttatcgata
    19441 gctaatatga ttaaatctaa attgctttat tcatgttcta ttataccata tccaccatta
    19501 ttacgcttat aaactactgc tatttcatct gaatctatgt tcttgaacat ataaaaatca
    19561 tgtcctatta attccatctg taatacagct tcttcttcac tcattggctt aacactaaat
    19621 ttcttacgtc tttgaattac taattcttga ttttcatccc cataattctc ttgttcatca
    19681 gctagattta tctctgcatc ttggaatctt atactcttgt tgtctttatg tttatcttgt
    19741 aatctctttt tatatttttt taattgttta cttaatttat catatacaac atctatagct
    19801 gtgtataaat tttcctgcat atcttctgct ctaattatag gaccatttac agtagctatt
    19861 gttacttcta ttttttgtct tgcttttctc gcacttactg taacttttac atcagtgtct
    19921 ggatgaatgt aattatctaa cttacttagt ttagtttcga ttttattttt tattgcatca
    19981 gttaattcga tttgttttcc agatataatt atgttcataa atacatctcc cttcaattat
    20041 gccagtataa gaaaatttat actttaataa tatattctac acgaactctc ataatcctct
    20101 ttttattatt tacttttatg attttttcta ttcaattgat agaattattt atcattttta
    20161 gttacattga tacttatgtg gattaatatt attacaaaca cctgtggata atgtggataa
    20221 aactgttaat aactcttgtt tttgtttatt taaagctatt tttactccta tttctatcca
    20281 caaaaatctc cattaattgt ttattaatat gtgaattcat gtcataagat ggtaatttta
    20341 ggaaattatg tgtattatat gccaatatac ctttataatt ttttaataaa tataaaccct
    20401 ctaaaacctc cataatctat cttttctttc attatttata tttaaaacta attaaaagtt
    20461 ataaagcata ctcaacaata atttcatatt taatacctat taacattcat atacccaaat
    20521 tataattaac ttactctctt tatttaaact aagtatttta tattcatata ctatcttgaa
    20581 attatattta cgagttgttt aagcttttgt ctatctatat cttcaaaagg actgttattt
    20641 attctaatcg ctgtaccaaa atgaaaatta cttgccttag ttaattcctt tatcttttct
    20701 atattattaa aattaagacc tccacctaaa agaattttta tgtgattaga actaagcatc
    20761 atattcttta tcatttgtat gttatcaact atacttcctt tccctcctga tgttaatata
    20821 ttcgtaattt tatcataatc cttcaaaatt ttaacactat ctattgtatt tgattcatct
    20881 attgctctat gaaatgtaac atcaagatta tcacaacatt tcaataaaac atttagattt
    20941 ttctcatcta tactattgtt tttatccaat acaccaaata caactccatt agcaccaatc
    21001 tctttaacca cacttatatc tttttgcatt atacttatat cttctttact gtatacaaaa
    21061 cttttcgcat gatgtcttat cattacgttc acaggtatct ttacactgtt aacaacactt
    21121 tctataagac caaaacttgg tgtcaatcca ccttcagtta aagcactaac taactctatt
    21181 ctatctgcac cacaatcttc tataatttta gcgtcttcta ctgacattcc tattatttct
    21241 aacataacta ctcctttgct aattcatata ttgcatttgc aaatatcttt gcatttaata
    21301 ttatatcttc tatatccatg tattcatcag gattatgagc tattcctttt tgtcctggaa
    21361 atgaaggtcc aaacggaact atatttggca ttacttttgc atacgtacct ccattagttg
    21421 ttacgggagt tccatctaat gatgtaaccc tttcataagc tagctgaagc tttttaacaa
    21481 gattactctc tttatcaaaa tatacaggat taaaattaga aattacctct atatcgatac
    21541 tatttggaaa actagctttt atttcatcca atacatcttt caatttataa ctaaaatcgt
    21601 attttacctt tatatctaat atagtatcac tattttctat attcagctct ttatatgtaa
    21661 caagcacatt ttcagacata ttttctataa aacctaggta tacatcttct tcataattga
    21721 ttttactttt tattctaatc tttgccatgc ctttttcacc atatacaaca ggatatttac
    21781 aatctggtgt aaatcccata ataggtgctt tttctttttc taaataatat ggtatatctt
    21841 caaatccact ttcttcattt gtaccaaata ttattctaac tctcttatct aattttaagt
    21901 ttaattcttt aatagcatat aatccatata aggcagacat tataggtcct ttattgtcta
    21961 gtactcctcg tccataaatt cttccattag tttcttctcc cttataaggc tgatgcttcc
    22021 aaccatctcc ttcatgtaca acatctacat gtccaattac acaaacataa tcatcactat
    22081 ctccatgctc tgcataacca atataattat ccaagtttct aaccttaaat cccaattttt
    22141 ctgatatttc taatgcttta ttaagtgcct cccctacttt ttcgccaaaa gggaagccat
    22201 tttctgactc ccctttgaca ctaggtattt ttacaatatc tataatatca cttaataaat
    22261 cttcttttaa ctcatctatt ttattactta tgatattcat aaaaatctcc ttattataaa
    22321 actctatttt aattatgtaa ccactacttt actcacttac ttctattggt gcttttattc
    22381 tagcctcata tgcttccatc cactcatttg atataacctt atgtatagtc tttccatcta
    22441 ctctatttga aatatataca gtaggagatt cttctttagt tactactgaa aaagtaaaat
    22501 cagctatatt tgtagctact ccccattcac ctttattatt catggcaact aatgataaat
    22561 caccagcttt tcctcttctt ttgataagct gtttatcaag ttcatttact gcaatatcac
    22621 atgcttcttg tggatgcttc ccttctttca taagtctaac tatctcataa gatatacatc
    22681 ccttcattaa atcttctccc aaaccagtag ctgtagctcc tcctatacta ctatcaacat
    22741 agaatcctga accagatagt gcagaatctc ctattctacc tcttttcttc ataaacaatc
    22801 cacttgttga tgtagctgca cacatttttc cagttttgtc taaagatatc ataccaacag
    22861 tatcatgacc agcatatggg cttaatcctt tgtctaaagt ctcttttttt ctctttttat
    22921 aatgtaactt cgctctatca gtcaacatat tttttctttc aaatccattt ttatgagcat
    22981 aatcttcagc acctattcca actaaaaaat tatttacctt ctcataactt aacttcctag
    23041 ctatgctgac aggattagaa taatctctta taccagcaac tgcgccaata tctaatgtgt
    23101 taccatccat aaatgcagcg tcaagttcta cctcacaatt ttcatttgga agtccaccat
    23161 atccaaccga tttatagaat ggatagtctt caactcttct tacagcaagc tctacagcat
    23221 cacctgcttc catgcctttt tctaaatgtt ctgatgcctc agttattcct tctagggcca
    23281 ttctccatgt cgctatcatt ccccacatgt taaaattccc ctccttaaat tatatagatt
    23341 ttactaatgt atgcttatta taaatagtat aatatttaaa cttgctaata attaatactc
    23401 ttattgataa caaaactctt ctttcatcaa agttatatct tctttatttg ctattgcttt
    23461 tgccaattta catatgttat ttaatgaatc attaagacca attccacctt tttttggagt
    23521 cttaactata catatgtcat ttttatattc gtttatcaca tctatatttt cttctgacat
    23581 agctgcaaaa gctggtatat ctgttttatc atttatattt ttagacagta ttgctgacat
    23641 cttagaaaag ttttcgtaat taaagcttgg tccacagatt actacatcag ggtttaattt
    23701 ttttaccata gctatcatct tactcgttac ttcttcttga ttatttacaa aaaattcatc
    23761 cccacaaaat aaggtagcta ttaccttaga ttcatttaaa aattgctcca tcattacacc
    23821 tggtcctaat gggcttgatt ttccagcagg aggtatatta cttttctctt ttcctccagc
    23881 tccagcttgt atttggtcca atatcataac tattttcttc ataatcttcc tcctataata
    23941 ctaaatcatc aaaagatata tcatcatctt cctcttcaac agtttcattt tcttctctca
    24001 agtattgctt atctagcatt tttataaatg gtatatacat aaatattcct agtataagaa
    24061 gtactaattg taagactgca ccttgccatc ctgttgttaa aaaaccagag aatataattg
    24121 gagttgtcca cggtaactga actccatttg taagaggcac taatcctgct gacatacaga
    24181 agtaagctat tattatattt attgttggaa ctattgcaaa tggtatcaat agtattgggt
    24241 taagcattat tggtagacca aatatcaatg gctcatttat accaaatatt cctggtaaaa
    24301 ttgatagttt tcccattgac tttatacgtt tacttttaca tattaataac atagctatga
    24361 ctaatgatag tgtactacct gctccaccaa atgtcgcaaa catatcttgg aattgacctg
    24421 ttattatgtt tggtattttt gaaccagctt gaaaagcagc taagttttca gctgatagaa
    24481 tttttaatat tggattatac acagccccaa caacactact tccatttatt ccaaagaacc
    24541 agaataaatg taagaatata taagcgattg ccatagcacc taaactattt cctaatttta
    24601 ataatggcat ttgtaaaaac ttaaatataa attcatgtat acttccatat ggtgtagctt
    24661 caaaagctat cttaactaaa aagaaaacta ccataactat tgcacttggt attaatgctg
    24721 caaatgattt tgatacagtt ggaggaactc catctggcat tttcaatgtc catccttttt
    24781 ttacaactgc agcaaataat tttacagagg ttattgctgt tatcatacct acaaacattc
    24841 ccttagaacc catccaacct agtggtatac ctgttaccat gtaaactgat tctgttcctt
    24901 ctggtgtata tggtattaca aatggtgtta ttataaaaaa ggcaactatt gcaactgctg
    24961 ctgatgctat tgggtctaca tctatttgct ttgcataaga atatccaatc cctaaaactg
    25021 caagtagagt cattacttca aatgttgcta cagttggttg ttgcaatttt acagcccaat
    25081 ctggaccaaa aatttgacct acaaattcat tccatccttt tataggaaaa tttgctacta
    25141 ataaaaataa tgaacctatt attaataatg gtgatgatac taaaaaacca tctctaattg
    25201 caattaataa tttattttta cctatttttt cagccaatgg cataagtatt ctttccaatc
    25261 tattcatcta tccaccctca tttcctatta ttttttacta taattctacg cttgtttaga
    25321 ttttattagc tttatagcaa gttttaatac tttttcccca ttcatagttc cataatcaac
    25381 ttcattgatt atatctataa gttttccttg agcttcaaac tttggtttta actcctttag
    25441 catgtattta acttgtggtc ctaataatat acaatctgga tttttttctt caactatttt
    25501 gtcaatttct gctatcggaa atgcctctac ttctattggt aaattgtgtt catctgctac
    25561 cttctgcatt ttatctgcaa gtaaacttgt tgacatacca aagctacaaa ataaatatac
    25621 ttttcttttc attttttaaa tcccccttaa tttttttatt ttaatttttg aatttctttt
    25681 cttaacataa tcatttcttt tataaggttt ctctcactca tacaagtcat taaatggtct
    25741 tgagagtgaa tcaataaaat agatatatct gatttatctc ccccagcttc cttttgtata
    25801 agttcagttt gtactttatg tgcttttaaa atttcttcat ttgcattttc aattaattca
    25861 tctgcttttt taaaatcgtt ttcctttgca tagtcaagtg cttcataaag catagatttt
    25921 gcatttccag catgaattat aatctttaaa actatttctt ccattttttc ctcctaagtt
    25981 gcttctctac ttttagatta tttatacctt acaaacatat aatatcttat aaaaacaaaa
    26041 aaacatgcac aactttttcc atcacatgga aaattttgtg cttatccata gttcactatg
    26101 aattttatat aagaatatct tttacctttt caatgtcaca tttacttaga atatctagca
    26161 tattttcatc ctctgttaaa ttagatattt ctttaaataa ttctctaaat acttttctat
    26221 catcatcttt tttatacgct aacaaaagta taatctttat atcctttcca tttctaattt
    26281 ttattggtgt ttttaacctt gcaaaacata aaacagattg ttttatatat ttcatgtctc
    26341 catgagggaa taatattcct tttccaacat tggttggata tgacttttct cttgttataa
    26401 tagattgtaa atactctttt tctgcataat gtttttcaat taataaatta gttaaatatg
    26461 ttatagcttc ataaatatca tcatgttcta actctcttat taaataatca gacatcatta
    26521 atctgttcat aagtttatat gaagtgtctt tttcttttat tttgtttgtg aactctttaa
    26581 gtttattctc atcctcatca gtaaataatg gtgttgttat aaaaattggt ttttggatat
    26641 tttcatactc ttgaaatgca attataaaat ctatagtctt attaaagtta tctcttttta
    26701 aatcttcctc tcttaatgtt tcaataattt ttatgttatc aaatctcttt tctatcttta
    26761 cttttaatag catacttact ccaaaactaa atggacatac aatacttgcc tttttatttg
    26821 attccctttt gctgtatttt ctttctagag aggtttgaaa gtgaagtgta agataaccaa
    26881 tttcatcttc cgttatttgt tttcctttta attcaatttc tattgaactt gatattactg
    26941 taaataaaaa acaaaattta gtttttatgt tatctaaaag tggattttct aagtaaacat
    27001 tgcttttcat ttgatgcatt gtaacattca aatgacatat taattgttca taaagtaata
    27061 tatcattatt aaaatttatt cctgattctt ctgatactaa atttataatt ttttttgtat
    27121 aacttgctaa ttcttcattt agatataaag atttcttaat attattacta tttatttgtt
    27181 tgttcatacc caatattaaa gattctataa acaatttttc ttcataattt aatactatgg
    27241 ataaattaga tttcaattca tcttctatat ccaatataag catttttagc ttaagctctt
    27301 tcttagtatt tgatactttt aaagaatttc ccagccttat tcgtattata tttataagca
    27361 aaaatagcat caattgcttg aatgatatat ctgtaagtct tatatccata tcctcttcta
    27421 tagtaagcat tatgtttttt acaattatta tatctactat atggaagtac tctatttcat
    27481 ctatgtttaa tctgtattta tctatatatt taaataagaa tgatactaac attattctta
    27541 tgtctttctc atccccttca atatatatac cactgccttt tttagtcgag atatttaaat
    27601 tataattatt taatgctact gataatttac ttatttcttc tctgacaata tttttattta
    27661 tgtacaactt attagataaa tcatttaaag taactttttt attattacaa agtagtaaat
    27721 ttagtatctc aacttgctta tgaagctcac tatttactct tttaacttca cctcgcaact
    27781 tctgatttac cagtattttg tctgttccat ctccactaaa tttaatccca atattaggtt
    27841 ttcttttgat ataagcatta caaaaagtag ataaccattc atcaatatat ttgcaatcat
    27901 ttcttattgt cctttctgaa cactcaaaat cattggcaat cttattaaca tttataaact
    27961 cttcttttaa tagcaatgtt gttaataaat tttcttgtct tttattcaaa catatcacct
    28021 ctttatgact caacctaaat ttattatata taaaaaagag ctatacataa aggtatgcta
    28081 gctctctttt aatatgatat ttagctgacc tggtttttga ccccacactc gcctactgga
    28141 gggttcgctt gggttcgccg cactactact ctctctcgat tttattatcg gtaggtctta
    28201 cttctaagcc gcaccatgat cattaaccca atttttagtg ttaacttacg tggatccctt
    28261 tgcctgcgac tggcttggac tttcaaccac agacctaaat atcacttatt cattttaata
    28321 ttttaaacta aaattgtcaa tatataagat tattccataa tataattatc atttgctttt
    28381 gtaagtagag tcaatacaaa aaccttatta gcacctgata actttaaaag tttagaaatt
    28441 tcgtttgttg ttagaccagt agtaaatata tcatctatta aaagtatatt tttattattt
    28501 attaatttaa cattttcttt aacaacaaat acatttttta attcttcttt tcgttctttc
    28561 ttattcaatt tatatagcat tcttgtatat ttttttctac ttatgcaatc taataatgga
    28621 atatttacta ttttacttaa attaaatgct attttttgtg cctgattaaa acctctttta
    28681 tttagccttt ttttatgaag tggaacaaat aatatataat caaattttat gttttctaaa
    28741 tataattttt ctttcattat ttgagctata tacttagcca taaaggtttt ttggttatac
    28801 ttcagcccta acaccatctt ttttgtcaca tcattgtatt caatacaaga tattgattta
    28861 tcaaaataaa agtctttatt aaaacaataa ctacactctt caataaattc tttttcaatt
    28921 gaatgacgta ttattggttt tccacacttc atgcaaccat cttgtataaa attcatttct
    28981 ttaaaacaac ttttacatat tgaataagta tttgttttct ttatggattt atcacaaatt
    29041 atgcaactta tattctcagg atatataaaa tccaaacatt tattaatcat atttttaaaa
    29101 ttcttaataa aattatcatt gcatattttc atatttattc tatcaacaac ccttcttgtt
    29161 taaatttatt tagcttatat cctaaatttg aatacctttg attaactcta ttatttttta
    29221 tcatatattc aagatatttc acatctccaa ctaatacaac taattttttt gctcttgtta
    29281 ctgctgtata taataaatta cggctaagta acataggagg agcccacgct attggcaata
    29341 ctacaactgg aaattcactt ccctggcttt tatgtattgt tgtacaaaaa ctatgatcaa
    29401 tttcatctaa ttcatcatat aggtatgata caattttagt ctggtcaaat aatatataaa
    29461 tagttttctt atctttatct atgtgataaa catatcctat atctccatta tagatacctt
    29521 ctccactttc tttttggtct tctgtttccc atttttttgt ataattattt tttacttgca
    29581 ttaccttatc gccaactcta aataatcttt tagaaaaatt ttcttcaact ttaaattttt
    29641 cttttttgtt aagatacttc tgtaactcta tatttagatt agtaactccc aattcacctt
    29701 ttctcattga agataaaact tgtatatctt ttaatttatc aactttataa aatttaggta
    29761 atctttcatt aaccaatcct attatttcat ttaaaatttc ttcattagtt gattttctta
    29821 taaaaaagaa atctttacct tttgtattta gataaagtgg ttctccattg tttatcttat
    29881 gggcatttac aattatcata ctttcttgcg cttgtctaaa tatttcattt aatttaacta
    29941 catttatgat attagaatta atcatatcct taagtacatt tccagcacct acagaaggta
    30001 attggtcact atctccaact aaaattactc ttgttcctaa ctttatagct ctaagtaaat
    30061 tgtacattaa gataatgtct accattgata cctcatcaac aattattaca tctgaattta
    30121 ttgggtcttc ttcatcctta aaaaaagtta aatcatcatc tgttgaaaat cccatttcta
    30181 gcaacctatg tatagttttt gcttctttat tagaagtttc actcattctc tttgctgctc
    30241 ttcccgttgg agctgccaga gtcacacttt taccattatt ttcaaatata tctatgatag
    30301 cattaatggt agttgtttta ccagttcctg gtccaccagt tataattaat actccactat
    30361 taacagattc tttgactgct aaaatttgtt tttctgctaa cttaattttc ttatcttctt
    30421 ctaaaacatt aatctcgtta tctatatcta tttttaagtc ttcaaattca tactgtgata
    30481 attttactat ttgactacat actccatttt cagctaaata gtatggcata aggtatataa
    30541 gattttcatt gtttactttc tctatatgta ttttttgatt ataaactagc atcattacac
    30601 actcttttat tatttctcca tttagctcca ataatttttc cgaatcttgt attagaacat
    30661 gctctggtaa atatgtatgc ccattactta aagatttatt taaagtgtat aagattccct
    30721 gacaaattct atctttagag tttttatcta taccaatttt acttgctata ctatcagcta
    30781 ctttaaatcc aattcctctt atatcttcag caagttggta tgggttttta tttataactt
    30841 ctattgcact gcttttatat tttttatata tttttaggca gtaatttggt gttattccaa
    30901 aaggagatag ctgtattatt atatttctca attctctgtc ttcttcataa ctttttacta
    30961 tttgttttac ttttttactc cctatacctt ctacttcttg tagtttttct ggtgaatttt
    31021 gtatcacctc taacgtatct acaccaaact tatcaattat tctttttgcc attttttcac
    31081 caataccatg tatcattcca gaagataagt aaacataaat tccttctaag gatgatggtg
    31141 ttactggcat aaaactattc acttcaaatt gagtcccata aatcttatga tttacccact
    31201 ttccttcaac ttctatgctt tctccaattg ctaaagtagg catacatcct acaaccacaa
    31261 tttcatcatt ttcatttacc aggtgagcta ttgtataacc attatcttcg tttttaaaga
    31321 ctatttcact tatcattcct tctaattttt ccatttttat ctcctaaaaa tactaataat
    31381 cgctccattt aaatgttagt ataattttat atattaaaac tatgataatc gtagaaaagt
    31441 tttatatttt tatacttaac gtaatttcca actattatac attttatcag aaacaaaaaa
    31501 aatctgcatc cataaaatat ggtaccatga aatacaggta ccatatttaa atagctattt
    31561 tattttaatt actctatatt tagagtataa attaaatttc ataagtatat tacagtacta
    31621 acttatttca gatttattct ccttgtaccc ctcagtttta gtaattcttc tataaagcat
    31681 acatagtaaa attaaaattc ccatgtaacc tgtatatgga tatagtgtac ctactaactt
    31741 atcaaatggc agtaaacctc ctatacaagc taatatactt accactattg ttataatttt
    31801 aaacttaggg tggtcatctt ctacaaatcg gtttgttact gaccataaca atggtacagc
    31861 tgtagtgtat attcctagta aaagtactac tgagaataaa atacctatta ttggagatat
    31921 cttatcagct aagtaaagtg ctggtatctc ttttgtgtat atatttccta tgtctgaaag
    31981 taatgccaaa ttcatcatta tagctgctgc cataagtgct actccaccta ctataccacc
    32041 ccatacagca tctttcttat ttactgcaga agctcccatt cctgtcaaga atgttattac
    32101 tattattaca ttgtaacaag tataaagtac tcccgagaaa tatccatttg atgtagcagt
    32161 tttaatattt aaactatcaa ccatatttcc agcatttgat aaagcatcaa tattgctaaa
    32221 taaactaatt gctcctacta aaagtgtaaa tattattatt ataggtccta tattacctag
    32281 tattttagaa agccttgtca aacctaatga aacagttatt agggaaacga ttgccatacc
    32341 aatcctacct acatatggat ttaatccata gtactctgat aatgtagctc ctgctcctgc
    32401 aatcattatt actaatgttc caaataaaaa caatggacca aaccattcaa aaaatgttcc
    32461 aagatatttt ccacaatata cttgataaat ttttattggc tccttaagtt tcaattctct
    32521 tcccttatct ataacttctg ctccaaacca tgaaaatagt accatagaga ttattccacc
    32581 tataataccc gcatatccat aaaacgtaaa aaattgcagt atttcttgac cagttgcaaa
    32641 tccagaacct attacagtag caacataagc tccagcaaaa cttataaccg ttttaatatt
    32701 tactttgcct gacatacact actcccccca attaaaatta tttttaaagt gtaagtttat
    32761 taagattata ttagactcat tattgtgata tttcaatata tttttaatta tttaacatta
    32821 gttaacacat tcttaaccat cctttaacat atatcccata atatgtataa atttagtaga
    32881 gtattatata aaatgtattg accagattaa atactgttta ttcattatat gatgataaat
    32941 taacatttat taaaaatatt taactcataa taaaaaagct gttagaaagt aatcgtaaaa
    33001 ttacattcta acagcttttt agttaaaaat tattcaccta aagcatcttt tcttaactgc
    33061 tcaaccttgt cagttctttc ccaaggtaaa tctatatcag ttctaccaaa gtgaccataa
    33121 gcagcaacct ttttataaag aggctttctt aaatctaagt ctcttattat cgctcccggt
    33181 cttaaatcaa agtgtttatt tactaattca acaagttttt cttctgaaac cttgcctgtc
    33241 ccaaaagtat ctataaatat agataatggt ctagctatac ctatagcata tgcaagttct
    33301 atctcacatt tgtctgcaag accagccgca acaatatttt ttgcaacata tctagctgcg
    33361 taagcagcag atctatcaac ttttgtaggg tcttttcctg agaaagctcc tccaccatgt
    33421 ctagaatatc caccataagt atctattatt atttttcttc ctgtaagacc tgtatctcct
    33481 tgtggtcctc ctataacgaa tcttcctgtt ggatttatat aaattttagt ctcttcatca
    33541 agtaattctg ctggtataac ttccttaata acatgattaa ttaaatcttc tcttatttta
    33601 tcatttgata ctgtttcaca atgttgagct gatataagaa ctgtatgtac tcttacagct
    33661 ttacttcctt catattcaac agtaacttga gtttttccat ctggtcttaa ataatcaact
    33721 aaacctgttt ttctaacttc tgtaagtctt cttgataatt tatgtgccaa agatatcgga
    33781 agtggcatta attctggagt ctcattacat gcaaatccaa acattatacc ttggtctcca
    33841 gctccaactt tttctatttc ttcttctatc tcttctccag tcttactttc tagaccctca
    33901 tcaactccca tagctatatc tccagattgt tcatcaatag aagttataac tgcgcaagta
    33961 tcacaatcaa atccatattt tgctcttgta tatccaattt ctcttactgt ttctcttact
    34021 aatttaggaa tgtctacata agcagatgta cttatttctc ctgctactaa aactaaacca
    34081 gtagtaactg tagtttcaca agctactcta gattgtgggt ctttttctaa taatgcatct
    34141 aatattgaat ctgatatttg gtcacatatc ttatcaggat gtccttctgt aactgattct
    34201 gacgtaaata aatgtcttgc catttttatt cccccttatt tattcttaat ttttattata
    34261 ggttttacct tgtttttaat tttagaaatt tactcaaaat aaaaaaacct ctcctttata
    34321 agaagaggtt aataatcgta attacatact aattaactga cctcatcttt caagactttt
    34381 gtcttgtagg aattagcacc ttttcccatt tgggtggttg ctgggcttca cagggcctat
    34441 ccctcagcct ctcttgataa ggtaatcaag atttaagttt tgttttactt tactagctta
    34501 ctattttttt aaaattttgt caatattttt agtcatattt tttctattcc tttttttgta
    34561 agacaaataa aattttctat ctatctgaaa tttaaagtta ggtcttttta atgcttttta
    34621 ttcatatatt tttttgaagg gggtgttcct attgtattta gctaaagtaa actacagcga
    34681 tgatgatgtt atacagatgc taagttcagt tctaaaaact ataattaatg aaaatacgat
    34741 tgttgtttgc ataggaacag acagggctat aggtgatact ttaggccctt tagttggaac
    34801 aatacttaag aacagtaact ttaaataccc cgtttacggt acactagata accctattca
    34861 cgccttaaat atatatgagt ctttagatac tataaaaaat acacatatac aaggtaactt
    34921 cttggctata gatgcttgct tggggtcgca gagtaacata ggtaatatac agattagaga
    34981 aggacctatc ctgcccggaa aaggtgttgg taaaaaacta cctcaaatag gaaattattc
    35041 tatagtagga attgtagata aaattgatga aaataataaa ctttcattta ataatatacg
    35101 ccttagcttt atattagatt tagctgaaac aatagccttg gctttattag tatccaccta
    35161 atctaaatat aaactaaatg ataaaattct ttatataaaa aggtagatat tttagagtat
    35221 ctgattaaat actccaaatt atctaccttt ttacttttat atttcaagtt tttatttttc
    35281 tactaaagca aacattaatt cacctttaca gacaagttct tcacctacat atgccttagc
    35341 atctgcctta gctatatttt ttctaagagt tgtcatttca acttccatag ttaatgtatc
    35401 tcctggtctt acttctctct tgattctaac tttatctata cctgcaaata cacctagttt
    35461 tcctttgttt tcctctacag acatcattgc cactccacat acttgtgcta gagcttctac
    35521 tattagtact cctggcatca aaggatattc tggaaagtga ccttggaaaa atggttcatt
    35581 aactgttata ttctttatac caacagctct tttcccaact tctagctctg taatcttgtc
    35641 tactaataaa aatggatatc tatgtggtat taattttttt atttcatcta tatttaacat
    35701 tctaaactct cctaattatt ttcttttgaa agacccacca gtttcaagta agtctattga
    35761 acctaaagct attcctgtac cttttgcaac acaagataat ggttcatctg ctattgtaac
    35821 agttattcct gtcctctgtt ctattatttt atctaatcca tataataatg aacctcctcc
    35881 agtcattatt ataccgacat ctcctatatc tgctgctaac tcaggaggcg ttttttccaa
    35941 aacagcatga gtagcaacta ctatttgctc aacacattct ctaagtgctt ccaacatttc
    36001 tgttgaattt atagttatag aactaggaag tcctgtaatt aaatttcttc ctgttatctt
    36061 catatatttt tcttcttctc tcttaaatgc agaacctatt tcaaacttga ttttctctgc
    36121 tgttctttct cctataagaa gattgtgttg ttttttcata tatttaacta tagcatcatc
    36181 aaatctatct ccaccaacct ttatagattc acttacaaca gctcctccta gagatattac
    36241 agctatatct acagtacctc caccaatatc tataatcata ttaccattag gctgtgatat
    36301 gtctacacca gctcctatgg cagctgctat tggttcttct atgatatata cttctctagc
    36361 tccagcttgt ctcgtagcat cttctactgc tcttttttcc acttctgtga cacctgttgg
    36421 tacgcatacc ataattcttg gcataaaaaa tcttccaaat ccctttttat caactatctt
    36481 atctataaaa gattttaaca tcttctcagt tacatcataa tctgaaatta caccatctct
    36541 taaaggtctt atagcgacta tattacctgg tgttctccct atcatctttt tagcttcttc
    36601 tcccacagct aaaacagaat ctgttctttt gtctatcgcc acaacagatg gttcttctaa
    36661 aacgattccc ttaccactaa cataaacaag cacatttgca gtacctaaat ctatgcctat
    36721 atcagctcca gccatttttt caactccttt atttataata ttagattata ttataagcct
    36781 attttaatac tcctataata aagcatatac aaaaatctcg ctttaatcaa gagaaaataa
    36841 atcttttgag agtattatta ttttgctatt tataattact taatatattt ctttttataa
    36901 tttaattcaa taaaaaaagt aggtttttaa cctacatttt tttatgttcc ttctcatatt
    36961 ttaatttcgt tgctaatccc cctctaatat gtctctctga tttatttttg tccagcacat
    37021 ttttaacttc tttggcaagg gatggattta tttccttcaa tctttctgta acatccttat
    37081 gaattgtact tttacttact ccaaatgtct tggcggtttg tcttactgta gtgttttttt
    37141 caagtatata ttttgctacc actatggccc tttcctctat atgagatctc aaagattacc
    37201 cccctcacat aatagcttta atgatatata tgtaaaaaca ccaaaaaata taacaagctt
    37261 aaccaaatat gattaaactt gttatactat tacttaatta gactcattgg gtctatagat
    37321 ttttctccac tatacgcctc taaatgcaca tgtatacctt cttcactttc tatttgagaa
    37381 gtactaccta cagtacctag agattgtcct tctgttacct tctgttcttt cttaacacta
    37441 acatttttat ctagatttga atatactact acaatgttat tgtcactttt tattttgact
    37501 gattgtccat attcttcatc atcaaataca tctactacta ttccgtttaa tagagatttt
    37561 acttctttgc ctttagtaca actaatatct acacctttat gagtttccca aacatcaagt
    37621 gttttagaat aactaggctc tttttctgaa tatcctctta ttactttatc tccaatgtaa
    37681 tttaattttg ttgtactcga tttattttcc tcttttgact tagctttttc taagttttgt
    37741 tttgaatccg ttgcagtagg gatagcatct ttcttgtctt tttcaattaa atgtatttcc
    37801 tcttcactat ctttattagc attttccata attcctttat tagaagccaa tttatctaca
    37861 ttattatttg taaaccaaac tccacctact gctaataaac aaacacatac aaacaaagat
    37921 aaataaaaac catctttttc taacagcttt ttcttcattt tgcacctcca aatatatttc
    37981 tacatttgga ttattgacgt gtttttggca ttttatacaa ttattagtat atatctttta
    38041 tttttgtatc tgtgtagtaa tgtgataata tatcataata tttataaccc tcttctgcca
    38101 ttccttctgc tccccactgg ctcataccaa caccatgacc atatcctttt accacgaaat
    38161 ctatgtatcc ttctccaaat tttatgtcaa agtttgcaga gttcaactta aaaacagttc
    38221 taatgtcttt tccagtcaat tctttatttc ctaattttat tttttctaca gttccggcat
    38281 cacttctttt agttattgaa acttgtttac ttaaattatt cacatctatc acaatagtgc
    38341 tatatgccct tctaagactt ttaacaaaat ctgtgttact tattttaagt gttgacgcaa
    38401 atttagggga atacttatca taaggacttt ccacagactt taaataagga tattttgcag
    38461 aaaatacttc ttcactattt tctgtttttc ctgaagatgt agaaaaataa agaggaagta
    38521 tcgccttatc attataagtt attatttgac ctttagttcc tctaactgct tcttggattt
    38581 tggaatattt attcttaatc cattcttcac catttaattt tttaagagta tcataactct
    38641 tatattcttg acaatgttta taatcagtac atactactgc atttttatgt ttactagatt
    38701 taccatgttc ctgtttatat actacatatg ttctagctgc tacagattga gcttttaaag
    38761 cttctatatc aaactctgaa gacatctcac cagctagtac tccacataaa tagttctcca
    38821 tgtccatctt ttcggttttc cctgttatat gattatatac attgataatt ggtgcttttt
    38881 tatttacagt ttcatagttc actgtatttt tttcttcttt attacctttg tcttcaatat
    38941 cacttttttt aatagttttg tttatagata ctgggctctc tggtttttca gttaattcta
    39001 catttttata agaaactaaa gttataagtg atggaactaa cacagagcaa gtcacaaatc
    39061 ctaacaaaac aaccaatggg ttcttcatat actctcctcc ttagctttta aaaccttgta
    39121 tttaagtata tgaacaaccc tattaattta taactttctt ctataaacca attattaatc
    39181 ttctactatt tcgatttgac cacctagtgc tgttatcttc ttatctatat caacataacc
    39241 tctttggata tggtatattt ctcctatttg agtttctcct tctgctataa gaccgcataa
    39301 aataagggct gcccctgctc ttaaatcagt agcgtttact gctgcaccgt gtagctcatc
    39361 tacaccatta acaaccgcac ttcttccatc tatttttata ttagcaccca ttctattaaa
    39421 ttcagcaaca tgcataaatc tgttttcaaa aacagtttct ataactacac cagttccatt
    39481 ggctacagta agcatagcca taaattgtgc ttgaacatct gtaggaaatc ctggatgtgg
    39541 taaagttttt atatctattg gttttaatac ttttggacct acaactctta cagaattgtc
    39601 catttctgtt atttcacaac cagcttctct taatttagct acaactggtt ttaaatgctc
    39661 cattaaaaca ttttcaacag ttatatcacc ttttgtcata gctgctgcaa ccatataagt
    39721 tgctgcttct attctgtctg gaattacatt atgttctgct ccttttaact ctttaacacc
    39781 ttttattttt atagtattag tacctgcacc tttaacatct gctcccattt cgttcaagaa
    39841 gtttgctaaa tctactattt ctggctcttc tgctgcattc tctattattg tagtcccttc
    39901 tgctaaagaa gctgccatca ttatgttttc agttgctcca acagatggga aatctaaata
    39961 taatttattt cctactaact tttctgttgc tgcttcaaca aaaccatggt ccatttctat
    40021 ctttgcacct aaagctttaa atccttttaa atgtaaatct ataggtcttg ttcctatagc
    40081 acatcctcct ggcatagaaa ttttcgtact attaaatcta gcaagcaatg gtcccataac
    40141 caaaaaagaa gctctcatct ttcttacaag ctcatatgga gcttcacaag tttttatatt
    40201 gcttgcatca acagtaagtg tattttcttt atattcaact tctgctccta catgtcttaa
    40261 taaatctgat ataacatgaa catctcttaa atttggtact ccatttaatg ttgattttcc
    40321 gtttgctaat aaagtcgctg ctattattgg taaaactgca ttttttgcac catctatttt
    40381 aacactacct ttaagtggat tactcttttt tactattatc ttagccatat tttttgatct
    40441 cctcataatt aataatctaa ttttataatt ggtgtggcaa tatatatgag tgtttttccg
    40501 tcatcctcat tatatttaat tcctatattt aaattaattt tttcccctaa atattctaat
    40561 tcataatcat ttaatacttt actatatgct gttatagata aaaagtttac gtctttaact
    40621 tcatctattt gcttagcact catattatat aatatttttt gtaaaatatc atcatatttg
    40681 ttgttttgta acctttttgt gtattctcca acaatacaag cagacacatc tacttgagat
    40741 gaatatttat ttaacacatt ttctacgtta ctataaataa cctctttatg tttatatact
    40801 ttgttatcca atatgtcaac tactatgtaa ctttctttgt tatttttatt tattcctttt
    40861 atagaaattt ctttatcgct accttttata gtagcacata attgtatttt atcgccagac
    40921 cctttttgat tccaatttat tcctttttta tccaacttta gattgttaat tatttctata
    40981 aaaatattat gaaattcttt atttgataaa ttatgattta taacagaatt aattttaaca
    41041 ttataaaatt taaaatttgc ttctgatatt tcaagagctt tacttaatct attgtatcta
    41101 gtatttatac ttgtatctgc ataagatatt gtcattccta taatcattaa tataaaaaag
    41161 cttatagcta attttacttt tttcatagta aaaaatcccc cttaaatatg tttttctgta
    41221 taatagaatt attaacaaat ttaagagaga tatactttct caatatgtat ttttatacat
    41281 ttttgtattt ttcatctaat aatctctttc aaactcttca atctcaattt tctctatcct
    41341 tctcctggac ttgccaattt cttatatgta tcaaatacat cttgcattaa ttcttatata
    41401 ttctcttctg taatataaat tacttagtct atacttaaat ctataatcta taatctataa
    41461 tctataatct ataatctatt catattttac caacaaaata aacagataat acttttttat
    41521 caatttccat agctccaaat gaacatacct aagtacactt cccaatacac aatttacaca
    41581 ctcttcctaa taaatcaaaa acacctttgt tttaaacaac tctattgcac tttcaaaaac
    41641 tttatttgtg ttctcccact tcaattaaat ttgaattatc aagactccag cccatccatc
    41701 catcactata aagggaggta ttttccactc ctatgacatt tgcatatgtt aatacttcag
    41761 cagcacgcca tccacttcca cacataaata taagctgttt attcacatct atattttcct
    41821 tgtcccacat ttctaaaatc tcatatttat ttctcattgt attatcaata ttacgatatt
    41881 cttctagtga aacactatca ctacctgaat gtccatataa agctcctggt atacgccctt
    41941 ttttatcata atatgtatat ccagatactt ttcctatatg ttcatcccaa gtacggttat
    42001 ctactagtat aaacttattt ttttctttta gtttttgtct taattcagat gtagtaacaa
    42061 ttaattgtga gttaactggt atatctgctc caaaattagt acatgaatgt tttggattac
    42121 taataaattc taattcatat cctgctgata accatgagtt tgttccacca ttcaaaactc
    42181 ttacatcttt tactcctata tatctcaata taacagctag tctataagat gccataggtg
    42241 tactacttga aactattaca gtatcatcct ttgttaatcc atagtctaaa gcaaacttag
    42301 ttaagttatc atcattatca agcatccatg ttggaggagg ttctataata tcagtattta
    42361 catgaacact tgtaggtata tgcccttttg tatacgattc ttctctccaa ctcgcttcaa
    42421 tcatttttat attctttgaa tcttcaaatg tctcaggaat ttttccatct aatatatctt
    42481 ttattataaa agcaggaact atcatttgat aatttttata tctttccatt ggaagatttt
    42541 cgtcgtctgc ccattgttta atatcatatt tatatagata tttatatcct tttttagata
    42601 aataatctgc tacaaccaaa gcatcttttc catttgcatc atacaatact atatttttat
    42661 ctaaatcaat tcttttagtt ttcaatgctt gttctaacac ttcatctttt ctatctgagt
    42721 atacacttaa ccaattagca gaaaaatcta ctgctccttt tatatgtcca cctcttttta
    42781 ctccatctaa cttccagcca ttataagcat catttaagcg agtatcaact ataacccaag
    42841 cgttatcttg cactttttct tgtaaaactt cagtagatat tgccttaaga ttaacaaaat
    42901 aatcttcttt cttttctttt ttaaaatcat ttgtcataat ttatactccc aatttaaaaa
    42961 aatttttatt tgaaattatt ttactaaaat aaagtaattt tcttatactc tattagcttc
    43021 attatattct tttataaata gttccttata ttcttatttt aaactactca ctttatctta
    43081 tcacaaggtt actaatacct tgtattttaa tttttctcat aagctattat ttttttatct
    43141 gatattgact atatgtttat taagtactca ctatatttta tatgaactat atttatcgtt
    43201 ccctatacct ggtatggtct atatatttat cattttacag atgatttaat atcaatcttt
    43261 ttataaaatt tattatagca aaaacaaaac aaatttaata tttatctaaa aaactcatcc
    43321 tataaaatac aaataacagg atgagttctt ttcaataaat attatctatt taatttttaa
    43381 tctgttttta ttcaactgtt actgatttag ctagatttct tggcttatct acatcgcatc
    43441 ctcttagtac agagacatga taagcaagta attgcattgg tacaactgct aatattggtg
    43501 ataaaatatc atctgaattt ggtatataga ttattttatc agcagctttc tcaacatcct
    43561 tattatggct ttgagctatt gctactacat aagctcctct tgctcttact tcttccatat
    43621 tagaaaccat tttttcaaat aacttttctt gagtagctat ggcaattaca ggagttcctt
    43681 tttctattaa agctattgtt ccatgcttta gctctcctgc tgcaaaagct tctgcatgta
    43741 tatatgaaat ctcttttaat ttcaatgaac cttccattgc taagctatag tctatacctc
    43801 ttcctaaata gaatgcatgt tcagaactaa caactgtttt agcaacttct tttatatatt
    43861 cttcattgtc tagtatttct tgtatttttg atggtatttc tttcatctta gaaatcatac
    43921 tatcataaaa ttctctagtt attgttcctt ttttgatagc aaagtctaaa gctatcatgt
    43981 ataaagaagt tatttgagta gtatatgcct tagttgatgc aactgctact tcaggtcctg
    44041 cccaagtata gaatacatca tctgattctc ttgctataga tgaacctaca acattagtta
    44101 ttgaaagtat tcttgctcct ttagcctttg aatctcttaa tactgctaga gtatctgctg
    44161 tctcaccaga ttgactaact aatattacta atgaattttc atctacaaat gggtcgctat
    44221 atctaaattc tgatgctata tcagttatta ctggtatatt tacaaatttt tctatggcat
    44281 acttaccaag taatccagca ttatatgctg ttccacaagc cactatataa actttattta
    44341 ttttttctaa gtcttcttta gaaatattta tactgtctag aattatattt ccattatcat
    44401 caagtcttct ttctaaagtt tctcttactc ctgttggttg ctcatgaatt tcttttgaca
    44461 taaagtagtc atatccacct ttagacgcag cttctacatc ccaagttaca tgaaatactt
    44521 ctttttcaac aagatttcta ttagagtcat aaactgttac attttcgtct tttagatgaa
    44581 ctacttctcc attttctaag aaataaacat ctctagtata ttttaataat gcaggtatat
    44641 ctgatgctat aaagttttca ccttcaccaa caccaactac aagaggacta tcttttctta
    44701 ctgcaactaa ttcatttcca tgttctttac atataacacc taatgcataa gctcctctta
    44761 attttgatat agttttgtat acagcatcta ataaattacc ctcatagtat ttatctacta
    44821 aatgtgctat tacctctgta tctgtttgag attcaaactt aacaccttca gaaattaatt
    44881 cttcttttat ttccatatag ttttctatta tcccattatg aacaactgct attgttttgg
    44941 cttgattaaa atgaggatgt gagtttacat cagatggttc tccatgagtt gcccatctcg
    45001 tatgccctat acctaaattt ccatcaatag gattcttttc taagtcttct gcaagtacag
    45061 aaagtctacc tttaaacttt ctaatattaa gttctttttc attagaacta ttaactgcta
    45121 ctcctgctga gtcataacct ctgtactcta gcttagaaag cccttctact ataacttctg
    45181 ctgcctttct acttcctaaa tatccaacta ttccacacat tatttgtgtc ctcctaaaaa
    45241 tattatttat atattttaag agttaggtca tataagttta ctttggcttc cctttgtcca
    45301 taggattgct cctattattt aaagaagtct ttcgatggta aacacaccgc agagcatccg
    45361 ccgacaattc gattaactct gacctcgtca acttagttcc tatattactc aataattatg
    45421 tctataacta agttctggcg cttagaaagg tgtcctcagt atttatatct gagaataccc
    45481 tttaaattac gataattttt cttgtataag attagctaag tttgttgcta attcttttat
    45541 ttgaccttcc tctttaccct ctaacataac tctaactaat ggctcagttc ctgatggtct
    45601 tatcaaaact ctaccatttc cgtctaaaat agattctatt ctttctatct cagtttttat
    45661 ttctggatat tccatatatt tgttcttatt ttcatttttt attgttgcat ttactaatac
    45721 ttgtgggtat tggctcatta ttgatgcaat ttctgataaa ggtttctttt cttgcaagat
    45781 tatatttgca agtattagag aactaagcac tccatctcca gtagtgttgt aatctaaaaa
    45841 tatcatatgt ccagattgct ctccaccaag attatatcca tttttaacca tatcttctaa
    45901 aacatatctg tctccaactg ctgtagtaga taaatttatt ccattttcct tagcagctat
    45961 tgtcaaccct atattactca taactgtaac taccaaagta tcttgtgcca atttattatt
    46021 tttctttaaa tttaaggcac tcaatatcat tatatggtct ccatcaacaa tttgaccctt
    46081 ttcatttact gcaattaatc tatcagcatc tccatcatat gcaagaccta agtcagcatt
    46141 atgttccaaa acagcccttt gaagttgttc tggatgtgta gagccacatt tatagtttat
    46201 attatttcca tctggtgaac tatttattga aattacactt gctcctagtt catcaaacac
    46261 tattggtgcc actttatatg acgcaccatt agcacagtcc aaaactactt ttaatccctt
    46321 aaagtcagtg cttattattg attttaggta gtctacatag tctctttgtg cacaatgttc
    46381 atgtaatttt cttcctacat tttcaccaat tggaagacaa tcaattttgt ctatatcgtc
    46441 tatatattct tctattttca attcaatttc atcatctaat ttatatccat tcttattaaa
    46501 gaatttgatt ccattatatt caacaggatt gtgagatgca gatataacca caccacaatc
    46561 agcaccatat tttctagtta aatatgccac tgcaggtgtt ggtattattc caacagtaat
    46621 aacatcacat ccaacagaca taagtcctgc tattaaagat gcttccaaca tatcacctga
    46681 tattctagta tccttaccta ctactacttt tactctgtgg tctccttgag ctaagacaaa
    46741 tccaccagct ctaccaagtt tatatgctaa atcacatgtt agttctgtat ttgctactcc
    46801 tctaactcca tctgttccaa aatactttct cactaaagat tctcctttca taattgaaaa
    46861 gcttgtaatt tgtattatat ttttatagtt cataaaatat cattataggc ttaatttcag
    46921 tcataaaaat attttaatac ttatcagcaa aaaagacaat agaaataatt ctattgtctt
    46981 ttttttgaca tctttttctt tattagttag ttgctttaga acatgtagca tccatacctt
    47041 tttgtaaagc ttctctgttt aatggaacga atttttcttt tctaggtccg aaaacttttt
    47101 tgaatgcttc tagtacagat tctatatcta cagtatcaga tacttttaag taagcgccta
    47161 acattatcat gttagcaact ttatcatttc ctaattcagc tgctaattca tttgctggta
    47221 tataataaac atctacatct gttctatcaa ctttttcttt tattaaagaa ctatttacta
    47281 ttatttttcc accaggaata acatcatctt tgaatttttc aaatgctggt atatttaata
    47341 atatagctgc agttgcatca tctgttataa gtggagaacc aactggctca ttagatacag
    47401 ttactgcaca gtttgctgta cctccacgca tttctggtcc ataagatggt aaccaagaaa
    47461 cttcttttcc ttctagcatt cctgcataag taagtaattg tcccatagac ataacacctt
    47521 ggcctccgaa gcctgcacat attactctag ctgtagacat ttacttcacc tcctcaactt
    47581 caacattttt gaaatttcct aatggatagt atggtatcat gttgtctctt aaccattgta
    47641 aagcatcgtt tggagctagt ccccagtttg taggacaagt agataatact tctactattc
    47701 caaatcctaa tcctgcttgt tgaacttgga atgctttctt tatagctttt ttagcttgtc
    47761 taacatgagc tggagtatca actgctactc tttctacaaa tacagctcct gttaatgtag
    47821 ctaacatttc acttactctt attggataac cttgagtttc agcatttctt cctgattgag
    47881 cagtagtagc tctttgtcca actaatgtag ttggagccat ttgtccacca gtcataccat
    47941 aagttgtatt gtttacaaat atagtagtta ttttttctcc tctagcagct gcatgaacta
    48001 tttcagcagt accaattgaa gctaagtctc catcaccttg ataagtgaat actgtatttt
    48061 caggatgaac tctttttatt cctgtagcag cagctggcgc tctaccatga gcagcttctt
    48121 gagtgtcaca gttaaaatat ttatatccta aaactgaaca tccaactgga acaacaccta
    48181 cagcatcacc taatactcct agttcttcta atacttcacc aactaatcta tggattatac
    48241 catgtgtaca tcctggacag tagtgagttt gagtatcttg taatccttca gttttcttaa
    48301 atacaacagc cattatctag cacctcctgc aaccaattct ccggcaataa tttttttagc
    48361 tttttcaact atttctgctg gtgttggagt cattcctcct ggtcttccat ggaagtaaac
    48421 tggtaattta ccttctactg ccattttaac atcttccacc atttgtccca tactcatttc
    48481 aacagtcaat atgtttctag cattaggaat ttggttgaat gcttcgaatg ggaatggcca
    48541 taatacttta ggtcttataa gacctgcttt tattccttct tctcttaata tatcaattgc
    48601 gctttttact actcttgaag tagttccata agctgcaaat acaaattcag catcttctgt
    48661 tttgtacatt tcgtattgta cttcattctt ttccattgca tcaaattttt cttgtaaatg
    48721 ccaacaatgg tcttctagta cttctggctc taagtataga gagtttatta cattaggttt
    48781 tctttttcct ttagttccaa cagttgccca atctttagga ggcaattctc ttttcttctc
    48841 aggagctcta aattcaactg gctccatcat ttgacctatc ataccatctg caactaccat
    48901 aactggtgat ctgtaataat ctgcaacgtc aaaagcttcc attatcatat caacagcttc
    48961 ttgaactgta gctggtgcga atactggagt tctgtagtct ccatttcctc cacctcttgt
    49021 agacataaag tagtcagctt gtgaaggttg tatacttcca agtcctggac cacctctcat
    49081 tacattaagt acaacacaag gaacttctgc tcctactgca tatgttatac cttcttgctt
    49141 taaagcaact cctggtgaag atgaagaagt cataactctt gctcctgcac ctgctccacc
    49201 ataaaccatg tttatcgcag aaacttctga ttcagcttga acgaacgctc cacctatttt
    49261 aggtaactct cttgataaat attctggtaa ttcactttgt ggagttattg ggtaaccgaa
    49321 gaaatatttg caaccagctt ctatagctgc ttttccaaat gcttcgttac ctttcataag
    49381 tatcttagcc attaaaattc ccccttaaat attaattaaa ttaatctctt tctactgtta
    49441 taactacatc tggacacata gttgcacaac ttgcacatcc tatgcatttt tccatttcaa
    49501 aaacagttgc tgggttatac ccttttttgt ttattacatt tgagtctaat tgtatgattt
    49561 ttactggaca tgcttcaaca cacaatccac aacctttaca acgttcttga ttaaaagata
    49621 cttttccttt agccatttac ctaagcctcc ttaaactttc tatatatttg agctcaaact
    49681 acatccagtc ttctctcata tataatttta taggaaaaat ttctccttct aaatcttttg
    49741 gtaactgttc aacaagattt tctaaacatg caacatatct tatcggtata ttacattttt
    49801 cagaaacttc ttttgcaact ttctgacctc ttaaaacatc atcaatagta gtaaacctaa
    49861 taagatgagt attattaatt agacctgtta cctttaattt agaagatttt tctatttctt
    49921 ttatatattg gataacttct tcagaagttt gagttttctc cctatttgca tttattacaa
    49981 aaagcatatc ataatcgcct tcttttaaca aatgactaaa tcttcctata accctagcac
    50041 ctacattatc tccacctaaa tctataacag aattgtatga atggtctacc ataggagaca
    50101 ttacctctgc tgatactgct ggtaaatcta atgttggagc attaattgag ctatctattg
    50161 gttgtatacc taaggatttc attaactctt tcttttctct agttctaaag tatacattta
    50221 ccacatctaa atcggctata gcaactttgc cagaaaccat atctcttaac ttaacaacat
    50281 agttcatcgc aaattcactt ttaccacttc catagtgacc agttatgatt cttattcttt
    50341 tatcattagt tatcataaac ttgagcctct tcttcaccag ttaaaactct aagtccacct
    50401 tgagctaatg caatcatttc atcttcacct ggataaactt ttacatctgc tataaattta
    50461 actctatctg caatcatttc tgtaaacatt tttgaatatg cgattccacc agttaataat
    50521 attgctttta catctccctt aagaactgca gcactagctc ctatttcttt agagatttga
    50581 tatgccatag cttcatatgc taatttagct ttttcatcac cagcttcaat tctttcttca
    50641 acttctctag catcattagt gtttaagtat gcaactaatc cgccattacc ttttattttc
    50701 tttttaattt catcttgagt atattttcca ctaaagcaca tttttactaa tgcacctact
    50761 ggtagtccac cacttctttc tggagagaaa ggtccttctc catctaatgc gtttgcaaca
    50821 tctactattt taccattttt atgagctcca acagaaactc ctccacccat atgtgcaact
    50881 ataagattta tatcttcata tttcttgttt atttctctag catatcttct tgctattgcc
    50941 ttttgattta aagcatgtac tacacttgct ctacttattt caggcatacc agaaattcta
    51001 gcaacatctt ctaattcatc tacaacaaca gggtctacta tgtatgaagg aacatttact
    51061 tcttcaccta tttgttttgc tattattcca cctaggtttg aagcgtgttc tcctaaaact
    51121 cccactttta aatcttcaat catagcagca cttactgaat aagtaccacc ttttataggt
    51181 ttaagaagtc ctcctctacc tactacagca tctaattcag atgtttttac tccaccttct
    51241 tttagagctt cttctattac ttgtttacga aattcaaatt ggtcagacac cttctcatat
    51301 tttcctattt cttctgaaga atgtcttaaa gttttttcaa atactaaatc ctcattatca
    51361 aatacagcta ttttagttga tgtcgaacca ggatttattg ttaagatttt aaatattttg
    51421 ctcatttgcc tatttccccc ttaaaattat gcctttgctg ccattaaaac acctaaagct
    51481 attgagttta gtttagtttc ttcactgtct gctctagaag ttaatattat tggtgcttta
    51541 gccccaacta taactcctgc attttttgat tttgagaaga ataccaaagc tttatataat
    51601 atgttaccac cttcaatatc tggggctaat aatatatcag ctcttcctgc tacaggatga
    51661 tttatacctt tatgtttagc tgcttctaaa gatactgcat tatcaattgc aaaaggtcca
    51721 ccaaccatac aacctttgat ttctcctctt tcatacattt cttctagttc tttagcttca
    51781 actgtatctt tcatttttgg atttactttt tcttttgcgc atattgcagc aacttttggt
    51841 tcacttatat ctaatgaatg tgctactgtg caagcatttt ctatgatttg ctttttagta
    51901 tttgtatcag gagctaagtt catagctgcg tcagttacga aaaataatct atcatatccc
    51961 tctacatcaa atactgctac gtgacttaat acatttccag ttctaagacc tacttcttta
    52021 tttaaaactg cttttagtat tattgatgtg tctactaagc ctttcattac catgtcggct
    52081 tttccttgtg aaactaattc aacagatttt agagatgctt ctgctaaatc ttttatatct
    52141 atcagttcat aattttcgat atccatgtct atgctttttg caatttcttt agtcttttct
    52201 atatctccta ctaaaatggc atttgctatt ttttcttttc tagccatttc aactgccatt
    52261 aaaacttctt tatcttggca acatgctact gatatagttt taggtcctct ttcttttgca
    52321 aacttaatta cttcttcaaa acttctcatg catttccacc tcatcttgaa ttttttgaaa
    52381 tagaactttt tatatctcaa ttaaattata actcgttcag caacgttttc ctagagataa
    52441 ttgaaatatt taattcaaaa tatttattta aatctattta tcagtctttt ttcatatatc
    52501 tagcgctttt tagatttaac aaatatctca ttgtccttat tttataatat aactaaaata
    52561 aacaagatgc aacaaaaaca taaaattaac aaacttaatt ttataggttt ttttgtcgca
    52621 tcttgtaaca actaaatatt cgaaatattt gttcattcca cttcaacaat attaggttct
    52681 atatttattt ttttaaattg atatgttgtt tcatatttta ttttatattt actatcttcc
    52741 tcaggacctt gtgataaatc aatatataat gaaatatctt ttttatttaa cttactcaaa
    52801 tcctccattg actctacaac aacttttata tctacatcag aaattacatt tggattatcc
    52861 atatttgttg ggatatttct taattcaata tctcccgcat tatataaaaa ttctgcactc
    52921 aattgttttg tatcatttaa tttaattgtt atagagctat cctcaagagt tataccctct
    52981 ggaatttcta agctaacttc tttttcttca ccattagcca aatcagctaa gtcaataggt
    53041 tttgtcttaa tataacttat tttgtctata tcttctttct ttccttttat tgtaacttgt
    53101 tccttactta atttatagtt tttcagtaca tcattatctt tattatcatt tagacttact
    53161 cttattggga caattttttc cttcaatagt tctatctttg cagtcacaaa ggatgaactt
    53221 aatgttactc cttcaacctt agttccatca ctatttaatg gtattaattg caatttttta
    53281 gaaaaatcat ctgtctcatt accaacatct agattagctc ttacactttt gacttcttta
    53341 actagagttc ttggacctga tacatcgaca aattccttac taagttcaat tttatttata
    53401 tttctttttg aatttccact tacttctacc tttatatctc ttttttcttt tatgtttttt
    53461 tcaagattta ctactaaaac atcatgctta aattctagag taacaccttg aggaatattt
    53521 gcttttaaat atacttcctt ctgtccttgt attgggtctt caatggttcc atatacatgt
    53581 atatcttctt ttttaacact ttgtaccttt gataaactac cttttatata tacatctgct
    53641 gttaattttt cgtctggata tataacaaga tttttatcct ttaaatcact catattactt
    53701 atagatacag gtatatcttc aaacccttta gtttcttcag ggtcaactac agccataaca
    53761 tacatccata atgcaattgc acttaaaaat gatattattt ttattttggt attatttttt
    53821 agtctattta tcatttaaat ataccacctt tgaaaaaact tcttgtttct gtatttgttt
    53881 ttaaattact acgtaatata ttcatcattc tttctctaga aatatctcta tataacttac
    53941 ctgctttagc aattgatacg ccacctgttt cctctgatac aatcaaagtt atacagtcag
    54001 acacctcact tacccctatt cctgctctat gtctagtacc caaatcttta cttaaatcct
    54061 tactttctgt caatggcaaa aaacatgcag ctgcttttac cttagaatct ctaattacaa
    54121 cagctccatc gtgtaatggt gtatttggta taaatatatt tattaatagt tgcctagaaa
    54181 tttcagcatc aataatagtt cctgtattta ttatatcact tattctagtt tctctctcca
    54241 ttatgataag agctcctatt ttttgtctag aaagtgaata taaagcttct acaatttctt
    54301 ctatatttct attgagagtt tcttcagaag tatttacatt ctttccaaat aaattaaact
    54361 ttgctcttcc tatatgttca agtcctgctc taaattctgg ttgaaaaatt ataagagcag
    54421 ctataactcc ataatctaaa gctttaagag atatccaata aacggtatgc aatttaaagg
    54481 tgttactaag ttgagttgct aataaaagaa atattatacc tttaaacact tgttctgctc
    54541 ttgtatcttt tataaacata aatattttgt aaaaaatata cgctactata gatatgtcaa
    54601 ttaaatcata tatactcatt cttaatatta tattaaaaaa tccatttaaa aaagaattta
    54661 tatctaacac agttttatcc tcctgtttga taacttctta attatttaca ctaagtatta
    54721 tactatataa atctaactct atacaaacta tttaactttt atgtaaataa ttctagtttt
    54781 atatttggag attgttaaat aatctctaaa cacattaaaa atatcaactt aataaataca
    54841 tatttcttat taaagttagt ttttactcaa ataactcaaa ccatcaaggc gcgaatacaa
    54901 aatagtactc gcgccttaat tcagttttat gttctaaaat atcttaatat atctttgttt
    54961 aatatatatt aattattata aattctataa tccacttatt aactataaac aaatacaaaa
    55021 tctaaatatt acttatcatc aatattattc cattagattc atttttatat taaagtaata
    55081 acttatttca tatctagatt agataaattt attttaatat cttactataa actatcatta
    55141 aaacttatta tgtataacta gatataatct cctacagtga aaataataca caatacctaa
    55201 agttatatat ccatttcaca gtataataat ttatttagta taacttataa atattacatt
    55261 aaattgtaaa ttcactatag tctctaattt tttataattt cttatactta ttgtttagac
    55321 aaaaatatgc tcatgaatct ctttataaat aatttcataa gttatttcaa tatataaata
    55381 ccataaagta tacaatataa tgtatataac tcttactaat tagttatatt tattatattt
    55441 aactgatgcc ttcataaaca tcttgtagac tattatacat taccctccgt atgtttacaa
    55501 tattaatgaa tatactgtaa ctctattaga atatactgta atttttacat agtttaaagt
    55561 ttataaataa aaagacacag gtaatataca tgtttcctgt gtctttttaa acaatataaa
    55621 agtttactat aatttatagt aaacttttct taatgagcgc acagggattc gaaccccgga
    55681 cacacgcctt agaagggcgt tgctctatcc agctgagcta tgcacccaag ttattatgga
    55741 gcgggaaacg agattcgaac tcgcgacttc aaccttggca aggttgcgct ctaccactga
    55801 actattcccg cttatttaat ttggcgacct ggaaggggct cgaaccctcg acctccagcg
    55861 tgacaggctg gcattctaac caactgaact accaggccgc gaatggtggg accaacaggg
    55921 ctcgaacctg tgaccccctg cttgtaaggc aggtgctctc ccagctgagc tatggtccca
    55981 tttttggagc gggtgaaggg gatcgaaccc tcacagctgg cttggaaggc cagaactcta
    56041 ccattgagct acacccgcat atttaattga attggtgact cgtaggggaa ttgaacccct
    56101 gttaccgccg tgaaagggcg gtgtcttaac ctcttgacca acgagccgtt ttaatggttg
    56161 cggaggcagg acttgaacct acgaccttcg ggttatgagc ccgacgagct gccaactgct
    56221 ccaccccgcg atattgtttt ataagtgccg aagaccggaa tcgaaccggt acgagaggta
    56281 agtcccgcag gattttaagt cctgtgcgtc tgccagttcc gccacttcgg cttttttggc
    56341 tccaagggtg gggctcgaac ccacagccta ccggttaaca gccggttgct ccaccgttga
    56401 gctaccttgg aacatttaac gtggctacgt cctactctcc caggcagttt cccaccaagt
    56461 accatcagcg ctagagagct taacttctgt gttcggaatg ggaacaggtg tatcctctct
    56521 gctattgtaa ccacataatc tttatgctta atatttctat taagttttta ata
//
LOCUS       DAYAOO010000016        55724 bp    DNA     linear   BCT 12-OCT-2024
DEFINITION  TPA_asm: Clostridioides difficile isolate ST8-SSI-h139-18
            SAMN40601845-rid21577343.denovo.016, whole genome shotgun sequence.
ACCESSION   DAYAOO010000016 DAYAOO010000000
VERSION     DAYAOO010000016.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN40601845
            Sequence Read Archive: SRR28438827
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 55724)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 55724)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-MAY-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-MAY-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002157583.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002157583.1
            Genome Coverage       :: 163x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/11/2024 16:19:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 4,038
            CDSs (total)                      :: 3,963
            Genes (coding)                    :: 3,930
            CDSs (with protein)               :: 3,930
            Genes (RNA)                       :: 75
            rRNAs                             :: 6, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 60
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 33
            CDSs (without protein)            :: 33
            Pseudo Genes (ambiguous residues) :: 0 of 33
            Pseudo Genes (frameshifted)       :: 7 of 33
            Pseudo Genes (incomplete)         :: 25 of 33
            Pseudo Genes (internal stop)      :: 11 of 33
            Pseudo Genes (multiple problems)  :: 8 of 33
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..55724
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN40601845-rid21577343.denovo.016"
                     /isolate="ST8-SSI-h139-18"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Denmark"
                     /collection_date="2018"
                     /collected_by="Statens Serum Institute"
     gene            817..2487
                     /gene="pdcB"
                     /locus_tag="ACGI5H_001107"
     CDS             817..2487
                     /gene="pdcB"
                     /locus_tag="ACGI5H_001107"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892771.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005515 - protein binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphodiesterase PdcB"
                     /protein_id="HFG9696821.1"
                     /translation="MREESNSLSLDHIEIFFELLSQSTEDYIFFWDINRNKFKISSAI
                     FDEFNLSKEIESDLVNCWSKIVYPDDVQIWKDDIQELLHGKKGEHNLEYRLINKYKEI
                     VWISCRGKVYVSDDPKTIFLVGRIKNIGEKNKFDSITGTWNREQFEHRMNYLIKEKIY
                     KNGAMFIMDIDNFKNINEKYGHSYGDKVLRAIATEVLEYLPKDVRLYRLDGDEFAFFY
                     PMCTKETIEKIYEKIQMYTNTQHEIESNKYYCTVTAGVAMYPEDGDNYLDLFKHADIA
                     LDIAKISGKNRIKFFSQELYENKLKVISMQQKLRECVENNFNDFELFFQPQVNAVTKE
                     VIGAEVLLRWHSSTYGEVSPVEFIPILEQSNLIIPVGKWIIKEAVKQCKEWHKINPDF
                     KISVNVSYIQLKEDFFRDFIVECLVEYQLRPEFLILELTENCWIPDINLLNDKFISLK
                     GIGVYIAIDDFGTGYSSLNYLKELSVNIIKIERSFVKNITYNSYEYTFLEYIIKLAHI
                     INLKVCVEGIESYEEYDIVKSLGVDIIQGFLFGRPVSASEFYKFQLSK"
     gene            complement(2609..3343)
                     /gene="pflA"
                     /locus_tag="ACGI5H_001108"
     CDS             complement(2609..3343)
                     /gene="pflA"
                     /locus_tag="ACGI5H_001108"
                     /EC_number="1.97.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004453705.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0043365 -
                     [formate-C-acetyltransferase]-activating enzyme activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate formate-lyase-activating protein"
                     /protein_id="HFG9696822.1"
                     /translation="MIKGKIHSIETFGTVDGPGIRYILFFQGCPLRCKYCHNRDTWDI
                     KSGKEYTVDEIITDALKYTSFMKFSGGGITASGGESTLQPEFLSELFKKAKENDIHTC
                     LDTSGFVDIETIDPVLDNIDLVLLDLKHMVEEKSIDLTGVGMDKALKLARHLESRNIP
                     VWIRHVLVPGITDDIDNLEKLGQFVATLKNVERFELLPYHSMGIHKWESLGIDYELKD
                     VPDATKEDVQKASEIISKFGVKVYNS"
     gene            complement(3503..5734)
                     /gene="pflB"
                     /locus_tag="ACGI5H_001109"
     CDS             complement(3503..5734)
                     /gene="pflB"
                     /locus_tag="ACGI5H_001109"
                     /EC_number="2.3.1.54"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888568.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0008861 - formate C-acetyltransferase
                     activity [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="formate C-acetyltransferase"
                     /protein_id="HFG9696823.1"
                     /translation="MNAWQGFKTGRWTKEINVREFIQLNYSPYEGNDSFLAGATENTK
                     KLWDEAMVLFKKERENGGTLDVDTKTVSGIAAYAPGYLDKELETIVGLQTDAPLKRAV
                     MPYGGIKMVENSCEAFGYELDPEIKDIFTKYRKTHNQGVFDVYTPEMRAARKSGIITG
                     LPDAYGRGRIIGDYRRVALYGVDALIEDKNEQKKSLEVSCMDEEVIRLREEITEQISA
                     LNELKKMAESYGFDISKPATNSKEAVQWLYFGYLGAVKDQNGAAMSLGRTSTFLDIYF
                     ERDLKAGIVTEEELQEYMDHFVMKLRMVKFLRTPDYNNLFSGDPTWVTECIGGMGIDG
                     RTLVTKNSFRMLNTLYTLGPSPEPNLTVLWSTKLPQGFKDFCSKVSIDTSSVQYENDD
                     LMRAYWGDDYGIACCVSAMRIGKQMQFFGARVNLAKTLLYAINGGVDEKSGVQVGPRF
                     EPITSEYLDYDEVMSKFEPFTDWLATLYVNTLNVIHYMHDKYSYEALEMALHDRDIFR
                     TMACGMAGLSVCADSLSAIKHAKVKTIRNEQGIAVDFEIEGDYPKYGNNDDRVDSIAV
                     ELVESFMNKIRKNKTYRNSYPTQSILTITSNVVYGKKTGNTPDGRRAGAPFAPGANPM
                     HGRDTNGALASLSSVAKLPYEHAQDGISNTFSIVPGALGKDMTERINNLSAMMDGYFA
                     QNAHHLNVNVFDRATLEDAMEHPEEYPQLTIRVSGYAVNFIKLTKEQQLDVINRTFHG
                     KMA"
     gene            6093..7088
                     /locus_tag="ACGI5H_001110"
     CDS             6093..7088
                     /locus_tag="ACGI5H_001110"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892772.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_process: GO:0098662 - inorganic cation transmembrane
                     transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="calcium/sodium antiporter"
                     /protein_id="HFG9696824.1"
                     /translation="MFITVVLFLVGFLLITKGADIFINCTVEIGKKTNISEIILGATI
                     VSFATTLPEFTVSLLASIDGHTTMSLGNAVGSIICNTGLALGLVVFISPFNVDKKMFF
                     SKSLLLIVSVIVLILLSLDGVITRGDSLLLIIILIFYMVNNYRSVVGKSDTKNRNIKN
                     NTIKDISTKKGKNYRGFSVLEIVKILLLFATGLIMMIIGSQILIESGVIIASFLNIPQ
                     GIVSLTIIALGTSLPEIVSSITAIRKNHHEISVGNILGANILNIVSVIAVSAIPNNIP
                     ILSQNRQLDIPFMILLLLIVIIPTLKSNKLSRIQGILMLFTYFLYISILYFMYII"
     gene            7179..8792
                     /locus_tag="ACGI5H_001111"
     CDS             7179..8792
                     /locus_tag="ACGI5H_001111"
                     /EC_number="3.6.4.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437464.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003676 - nucleic acid binding [Evidence
                     IEA];
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0004386 - helicase activity [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HFG9696825.1"
                     /translation="MNITKFEDLPISEGIKKAIAEMGFEEPSPIQAQSIPAILSGKDV
                     IGQAQTGTGKTAAFSIPILETIDPNNRSLQAVVLCPTRELAIQVSTEIRKLAKYSHGI
                     KTLPIYGGQPIDRQIKSLKSGVQVVIGTPGRTIDHINRKTLKMDNVKMIILDEADEML
                     DMGFREDIEMILSKIPEERQTTFFSATMPRGILELTKRYQKDPEHIKVVRKELTVSNT
                     KQYYIETRSSNKLEVLCRLVDVYDPKLSVVFCNTKRKADELVGDLQARGYFADALHGD
                     LKQTQRDIVMDKFRNGTIDILVATDVAARGIDVDDVECVFNYDLPQDEEYYVHRIGRT
                     GRAGREGMSFTFVFGKEMRKMKDIERYTKSKLIKHNIPTITDVEEKKVGTFFAQVKQT
                     IEEGHLTKQLQWLEGFCNDEDYAMVDIAAALVKLSLGEEMKEEIIEEKPRRERGDRKG
                     GTGAKDGMIRLFINIGRNQRVQAKDIVGAIAGEVGIPGKVVGTIDIYDKYTFVEIPKK
                     DAKTVIEKMKDIKIKGNKINIEKANKKKK"
     gene            9067..11052
                     /locus_tag="ACGI5H_001112"
     CDS             9067..11052
                     /locus_tag="ACGI5H_001112"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860951.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antiterminator"
                     /protein_id="HFG9696826.1"
                     /translation="MSMTYMDPRVFLILEMVLEEDTNTLEQFSNVLGVSTRTIRNYIN
                     QINRELKGGIAKIVKNEKGTYSIRIEDESKLIEIVNFNRGKLSNFINLNSPDERINYV
                     LDILTMTNNPITIDDLAEEICIGRTTLIKDLKKADRILAEYDLELKRKPNIGMILVGE
                     EMDIRLLILDRLYENYIDVLENVNQINLVKDYDIECLRDELKKLFKKEELYITEQVLR
                     DVERYIIMSVLRNLNGYKFEKIDKRFEVIRCSDEYTLGLKLKALLEKIFNIVLNEKET
                     IFLTMPLIGRKAPSTKLALSSIKINDSVKEVVDEVTSFLLETSGIDFKEDKKLIENLE
                     YHLYFALNRMRFNIRVKNPLLQEIKERYTFPYSVAKIAAMIIEEKFDLKICDHEIGYI
                     ALHFGSYFEKNSRKVLNVNRVAVVCGTGLGTAQLIRIKIGKILGESVEVNTFSDIEAK
                     ANLDLLKYYDLVFTTVDFKTDLDVPIFRVNALFNEESIKKEIENAILLKNSINLKSIK
                     KIEKNIPFIGKLIEEDKFFILNKSTFMENLEDMLEKLVHKGIIDIEFKKKVLKREKKS
                     STALDNYIALPHSVNTNGENLYLAFGILEKPVIWDTKEIRIIILMIIPDKNVDSTDLI
                     IKSYEEVLEVGRDKKMVEELAKAKSFDEFYKIITKRR"
     gene            11057..11491
                     /locus_tag="ACGI5H_001113"
     CDS             11057..11491
                     /locus_tag="ACGI5H_001113"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437466.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator GutM"
                     /protein_id="HFG9696827.1"
                     /translation="MDPVIFIIASLITVYLLNIFLGYLQLKDFNKNYIELKRKGRVAI
                     GRKKGRISSGTIVLILINDDGVIVETRKMQGVTVLARVKSFEGLVGKNLEYIEKSDLT
                     VYNKLLKKAILDAVKQYITFEKNKCEDTNNLSTDEECRMEVV"
     gene            11520..12080
                     /locus_tag="ACGI5H_001114"
     CDS             11520..12080
                     /locus_tag="ACGI5H_001114"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418408.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucitol/sorbitol transporter subunit IIC"
                     /protein_id="HFG9696828.1"
                     /translation="MTQFFQVLASGADSFMNLFRAGGQQFVGFVTDIVPLLVALLVTM
                     NAIINFIGTDRVERLAKKCSANIFTRYLILPVLGTFVFANPMTLSLGRFLPEKFKPSY
                     FAAASFSCHTMNGLFPHINPGELFIYLGIANGITTLGFSTADLAVRYLLVGIVANFIK
                     GVVTDYTTKFVEKQQGIALNSDIKIG"
     gene            12144..12644
                     /locus_tag="ACGI5H_001115"
                     /pseudo
     CDS             12144..12644
                     /locus_tag="ACGI5H_001115"
                     /inference="COORDINATES: protein motif:HMM:NF015569.4"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sorbitol transporter subunit IIB"
     gene            12684..13103
                     /locus_tag="ACGI5H_001116"
     CDS             12684..13103
                     /locus_tag="ACGI5H_001116"
                     /inference="COORDINATES: protein motif:HMM:NF019286.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sorbitol transporter subunit IIB"
                     /protein_id="HFG9696829.1"
                     /translation="MAFVAVLIGIINQSGIGNWVANLLTPLIGNVGGLVVLSIICSFP
                     LLSPFLGPGAVIAQIVGVLVGTEIGKGNIPPSLALPALFAINSQAACDFIPVGLGLAE
                     AEPDTVQVGVPSVLYSRFLTGAPTVLLAWLASFGLYK"
     gene            13144..13509
                     /locus_tag="ACGI5H_001117"
     CDS             13144..13509
                     /locus_tag="ACGI5H_001117"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437468.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucitol/sorbitol transporter subunit IIA"
                     /protein_id="HFG9696830.1"
                     /translation="MELIYSTQINKIGDNANEFLQHNMFVTFKDNAPQELENYCYIHS
                     ENNLVKEILTDDVLSINNVDYKITSVGELVNQNLSELGHITFKFTGEKDGAIGGTLYL
                     EEKEIAPIGVGTILKIIRK"
     gene            13610..14383
                     /gene="srlD"
                     /locus_tag="ACGI5H_001118"
     CDS             13610..14383
                     /gene="srlD"
                     /locus_tag="ACGI5H_001118"
                     /EC_number="1.1.1.140"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905113.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sorbitol-6-phosphate dehydrogenase"
                     /protein_id="HFG9696831.1"
                     /translation="MRKVALVVGGGRSLGEYLSKHLAKVGYDVAIADLNEDNVKKVAE
                     EIKTEFGCKSVGYSCNAIDERQVISTVKAIENDFDRIDLLVYNAGVAVSKKITDFGYK
                     DFKFIVDVNLNGYFLFAREVSKVMIAKGIEGRIIQINSKSGRVGSKHNSGYSAGKFAG
                     VGLTQSLALDLAEHKITVNALMLGNLLDSDMFESLIPQYAVKLGIPESEVKQVYIDKV
                     PLKRGCRFIDVANMLTFYASKEAEYCTGQSINITGGQVM"
     gene            14732..16876
                     /locus_tag="ACGI5H_001119"
     CDS             14732..16876
                     /locus_tag="ACGI5H_001119"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="molybdopterin-dependent oxidoreductase"
                     /protein_id="HFG9696832.1"
                     /translation="MDIIKKLSHGCTLDCHDCCKFNVYTKGNNVVKIEGDKNHPYTKG
                     FICKKGMAHLDRLNHKDRIKTPMLKVDGVWKEISFDKAIEIMAEKLTYYKEKYTSKSV
                     MHYDQYGSGSVLKYIGDIFFNFYGGVSRHKGGPCWSAGMHAQKYDFGVAKSHAIEDML
                     NSKSIFVWGKNPAYTTIHTMQIIKKAKEKGIKIVVIDPIYTKTAQIADKYVQVNPGTD
                     GALAIAMAKIIVEDKLYDEEYINSYVIGFEEYKKYLSSLELSFLIDECGVKENDIREL
                     VDLYTNKYSSINVGYGLQKYKNGGNTIRAIDALGAITGQIGFSGGGVNYANKVYPSVI
                     NSDPYNSQSYGEDREFYVSNISKFIEESLKNTSNKVNYASDELDMTSNKVNYVSDELD
                     ITSNKTDYISNELYNLSNKSIKGNIPIKMAVITKSNMLNQLPDLVELERVFSKIEFKV
                     CFDMFITDTATLCDMFIPCTNTLESEDIIYSSMTNPYITYNERAVKPAHKLMDEYYFF
                     MELAKKMGLNDYPFVEKRTYLEKVIEPLKRFDKNLDIEKLKNNYFTIHNPVAWEDKKF
                     ETPSGKYELYSESIKNLGISPTPVYISNKYKEIEDKNISFRLLTNHHADTLFSQHFMD
                     KKSIAQAYINRRMAKKVGIEDKDIVILRSKKAKINVQINIDDGVGNYIVKMYVGWWKK
                     HGNPNSLTDTGISDFGGQVTYNESMVEIIRQN"
     gene            16964..17299
                     /gene="spoIIAA"
                     /locus_tag="ACGI5H_001120"
     CDS             16964..17299
                     /gene="spoIIAA"
                     /locus_tag="ACGI5H_001120"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418414.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0045152 - antisigma factor binding
                     [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA];
                     GO_process: GO:0030435 - sporulation resulting in
                     formation of a cellular spore [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="anti-sigma F factor antagonist"
                     /protein_id="HFG9696833.1"
                     /translation="MVNYSLEHKNLYIEFMCSELDHHVANEIREEIDNLLSVNQVKNV
                     VFNFENINFMDSSGIGVIIGRYKKISNEGGRVSVINISSRVKKIFDLSGLNKIIGIYD
                     TYEEALSSL"
     gene            17313..17741
                     /gene="spoIIAB"
                     /locus_tag="ACGI5H_001121"
     CDS             17313..17741
                     /gene="spoIIAB"
                     /locus_tag="ACGI5H_001121"
                     /EC_number="2.7.11.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418415.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004672 - protein kinase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016989 - sigma factor antagonist activity
                     [Evidence IEA];
                     GO_process: GO:0006468 - protein phosphorylation [Evidence
                     IEA];
                     GO_process: GO:0030436 - asexual sporulation [Evidence
                     IEA];
                     GO_process: GO:0042174 - negative regulation of
                     sporulation resulting in formation of a cellular spore
                     [Evidence IEA];
                     GO_process: GO:0045892 - negative regulation of
                     DNA-templated transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="anti-sigma F factor"
                     /protein_id="HFG9696834.1"
                     /translation="MNNIMEVKFSAISENESLARVIVASFAAKLDPTVDELVDIKTAV
                     SEAVTNAIIHGYEEDSSKFVFLRCEIEGNTIKIIVEDEGYGIENVEKAMEPLYTSKPE
                     LDRSGMGFTVMKSFMDDVEVSSVKDNGTRIEMTKKINVPK"
     gene            17764..18528
                     /gene="sigF"
                     /locus_tag="ACGI5H_001122"
     CDS             17764..18528
                     /gene="sigF"
                     /locus_tag="ACGI5H_001122"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418417.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_function: GO:0016987 - sigma factor activity [Evidence
                     IEA];
                     GO_process: GO:0006352 - DNA-templated transcription
                     initiation [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="RNA polymerase sporulation sigma factor SigF"
                     /protein_id="HFG9696835.1"
                     /translation="MEVTVAREEKKPLLSHEETLELIEKVQNGDEEAKEILISSNLGL
                     VRSVVSRFLNIGYDREDLFQLGSIGLIKSIYKFDPKFNVKFSTYAVPMILGEIKRYLR
                     DDGMIKVSRSLKQIAIKAKMESEALTKKLGREPSIEELAKAIDVEKEDLVMAMEANFN
                     VEYLQGVIHEEEGSPICLIDKISMKGESEEEKVVDNILLKDILGRLDKRERQIIVLRY
                     FEDMTQSEIGEMLNISQVQVSRIEKKVLSKLKEYIS"
     gene            18808..19245
                     /gene="spoVAC"
                     /locus_tag="ACGI5H_001123"
     CDS             18808..19245
                     /gene="spoVAC"
                     /locus_tag="ACGI5H_001123"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418420.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003674 - molecular_function [Evidence
                     IEA];
                     GO_process: GO:0030436 - asexual sporulation [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="stage V sporulation protein AC"
                     /protein_id="HFG9696836.1"
                     /translation="MDKNYKKYVDQISPKPTYLKNYTLAFIVGGIICMIGQAINDLYM
                     KVGGLDKLGASSATSITLIFIGAFLTGLGVYDLIGKRAGAGSIIPITGFANSIVSPAM
                     EYKREGYVLGVGANLFKIAGPVLVYGIGSSILCGIIYYIFKMF"
     gene            19412..20425
                     /gene="spoVAD"
                     /locus_tag="ACGI5H_001124"
     CDS             19412..20425
                     /gene="spoVAD"
                     /locus_tag="ACGI5H_001124"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418421.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003674 - molecular_function [Evidence
                     IEA];
                     GO_process: GO:0030436 - asexual sporulation [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="stage V sporulation protein AD"
                     /protein_id="HFG9696837.1"
                     /translation="MKNKRIGKRTVKLENKPTIISTGTIVGPKEGEGPLKDYFDMIMT
                     DDLYGEKTWELAESKMVETASQQAIQKAGKKLSDVNYMLGGDLINQIVPASFAARELA
                     IPFLGIYGACSTMAEGLCIGSMLIDGGFADLVLSGTSSHYCTAERQFRFPLELGNQKP
                     MTAQWTVTGAGSVLLAPNGDGPKVKYVTVGKVIDEGIDDGNNMGPAMAPAAIDTIYSY
                     FEDTNDDPNSFDIIATGDLGTLGKQIAEDFLKEKGVDISKVYTDCGIEMFNLKEQDVH
                     CGGSGCGCSATVFAGYIYDKLRKKEFNKVMLVSTGALLSPTSTLQKQTIPCVAHAVVI
                     VNE"
     gene            20439..20801
                     /gene="spoVAE"
                     /locus_tag="ACGI5H_001125"
     CDS             20439..20801
                     /gene="spoVAE"
                     /locus_tag="ACGI5H_001125"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902150.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003674 - molecular_function [Evidence
                     IEA];
                     GO_process: GO:0030436 - asexual sporulation [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="stage V sporulation protein AE"
                     /protein_id="HFG9696838.1"
                     /translation="MLMDYVRVFIVGGIICLIAQVMMDYFKMQTPYVMVTYVTTGVVL
                     TFLGLYEPLVKFAAAGATVPIIGFGYSLATGVIKSIQSDGFLGIFLGGTTATAGGIAA
                     AIFFGYIMSVVFTPKAKP"
     gene            20984..22000
                     /locus_tag="ACGI5H_001126"
     CDS             20984..22000
                     /locus_tag="ACGI5H_001126"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888571.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HFG9696839.1"
                     /translation="MVTIKDIARNLGISYSTVSRCLNNNPNVSEKTKKKVVEEANRLG
                     FHFNVNARNLAKKETNRIGVIFSNNFNHQDTRKFFSDIMDSSINSIETNKYDFIIQPN
                     NNISGDSNVYKMVNGQMVDGLVIVSQSIKKEEYDFLKDNNFPHVFIYFKPSFIGEVDN
                     FFWDDNVYGGYIATKHLIDHGHKDIITVTSDDKSSKMHEDRTKGYLNAMEEANLKTEV
                     IKSKMDFESQVEFLEKYIDKIKKASAIFVQQDVPAISIIQELKTTYGINVPEDISIIG
                     YNNIELISYFRSHLSTIDDPREQVIKNGVDSLVNIINKKSTEHIPRKLYPRLIIRNSV
                     KRIK"
     gene            22375..23217
                     /locus_tag="ACGI5H_001127"
     CDS             22375..23217
                     /locus_tag="ACGI5H_001127"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418427.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3100 domain-containing protein"
                     /protein_id="HFG9696840.1"
                     /translation="MKEKAGIRNAIIAAFIITILAELIGPISFKVMGINVTLLSILWA
                     IFIGMAVSPHLLGRVIPALKKFIGDNEINVSPYLLSLTLYPLGIMFGINAGPKVGILL
                     QAGPALLLQEFGHMGTMLIALPVGVALGLGRSALGGTFSLCRDTALGIIGDKYGLNSP
                     EGIGTLGTYISGSIFGTLLFSFLAPVGVLLGFHPYALAMASGMGSGSMMGAATASLMN
                     TVPQMSEQILAYSATSGLITAVTGIYIELFLSLPVANYYYSKVAPVIERFRGRKTRRT
                     SNKL"
     gene            23232..23696
                     /locus_tag="ACGI5H_001128"
     CDS             23232..23696
                     /locus_tag="ACGI5H_001128"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437484.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9696841.1"
                     /translation="MEKTFKTIMEQIKIVLFIYIIICFGQMIALKTQAQDLLIGSVSG
                     FLLVIIAIIIKNFVKKPNLPGFAWATLVAFVLSLPISPVGDIIATNVGKINFMSTVTP
                     LLAFAGISVGNQLDILKTLSWKLVVISFIVMTSTYFGSAFISQTVLRLNGML"
     gene            23710..24855
                     /locus_tag="ACGI5H_001129"
     CDS             23710..24855
                     /locus_tag="ACGI5H_001129"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905116.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M20 family metallopeptidase"
                     /protein_id="HFG9696842.1"
                     /translation="MNELKAKIKEEIKLLSEEKKTSFEKVSDYLFSNPELAFEEYKSQ
                     KALCDLLEENEFNVTKGVGGLETSFEAVYSNGTNGKTVAFLAEYDALPGMGHACGHNI
                     IGTSSVGAGIILKEIMKKHNIEGTVKVFGTPAEERVGGKITMIKEGVFNNVDAALILH
                     PSDASMPDDISFAQVNLKFDFTGKASHAAAFPWEGKSALSGVIALFNSVNSMRLHLKD
                     YARVHGIITDGGSIHNIIPEKSTAIFNVRALSIEYLNEICEMLKNCAKGAAISTGTNV
                     EIVQLDEIYKEIKNDSELVNIVRQNFEVLGEDYVERDLSQGIGSTDTGNLTHEIPAIQ
                     AYIKLKENTATHTDEFAVAAGGEEGRVALIKAIKVLAMCGVDILYSK"
     gene            24899..25834
                     /locus_tag="ACGI5H_001130"
     CDS             24899..25834
                     /locus_tag="ACGI5H_001130"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418433.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1177 domain-containing protein"
                     /protein_id="HFG9696843.1"
                     /translation="MILKQVIEVYDILDKANANGEEVKTYLQGYGEVDVTVKELSSSK
                     GSTDLVKLTIPGKNGKLKGGDAPTLGILGRLGGIGARPEVIGFVSDGDGALVAIAVAA
                     KLLDMQRKGDILDGDVVISTHICPDAPTKEHYPTPFMDSPIDMMTMNENEVDSSCDAI
                     LSIDTTKGNRVINTRGFAISPTVKEGYILKTSDNLLDIMQTVTGKSPFVFPLSIQDIT
                     PYGNNLYHLNSILQPAVATDAPIVGVAITTEMPVAGCATGATNFSDLDSAGRFAIEVA
                     KLFGRNKCDFYDKEEWEMLIKRYGKLNRFQTFGIQ"
     gene            complement(26108..28717)
                     /locus_tag="ACGI5H_001131"
     CDS             complement(26108..28717)
                     /locus_tag="ACGI5H_001131"
                     /EC_number="2.4.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018112771.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016757 - glycosyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="transglycosylase domain-containing protein"
                     /protein_id="HFG9696844.1"
                     /translation="MNNDNDKNGNKIRRKKVSSSGNTNKPINRTSANKTRSTKNKKKS
                     KKSDKFKKLRVFGIVFLVLLVVGTAGTAGLVFASLRDVTPVTEAVLDKQTNQTTTIKY
                     ANGKTLSTAPSVNKKTPVPLDKISPYLQHAVIAIEDERFYEHKGVDIKGLFRSVLKTL
                     TGTKQGGSTIPMQVSKMLLTTEQQTIPRKIKDIYYAHEMSKTVSKDKILETYLNNFFV
                     GRGLAGAEAGARGYFDKSAADLTLAESALLAGSTKNPSRFSAYKTSKLEGNETKEDLE
                     NKLLFFVNTTDDDLDDPTQVDFDMIEKIKSWELISNDTYRQLKAGTLVVRKAVSNPEA
                     KKRQEIVLKKMLELKYIKQSEYDEAIKAKIEIKLPQSSDKVSSSVEDLIESEVINALM
                     EQGHTNDEAQNLFYNGGLIVNTTIDPKMQDALEEEFDRNSNFPGHMVGPDGVSQPQAA
                     MVILDYKNGEIRALAGGRNISGRKTLNRATNPHQPGSSIKPLAIYTPAIDTLKITQAT
                     ALSDSRGGYKFEENNKWNPRTTTAGHGSMSLRKALAKSSNTIAVKTAEMLGDSYDECV
                     DIMMDYLKNFGITTLKNNHSGSSEASDRKFPSLTLGGMANGITPLQMAAAYGTLANHG
                     IYVEPSIFTTITTFDGQLLVKNAPEEHKVVDPEVAYVVTDMLESVITEGTGGVATLPK
                     GMPVAGKTGTTNSAYDAWFVGYTPYYVGATYIGDDAGRKDDSGNTIKRREVPHGSTST
                     AKLWEKIMEKIHANLTVTEFEVPKNVYFTKINLEDGGKQSSGSKAAFIEGTAPTKVSS
                     QPSSEDTKKPDNNQPEENNNNNNNTGDNGGGSTPPDNGGNNGGGSTTPPDGGGNNGGG
                     STTPPDGGGTPAT"
     gene            28931..29629
                     /gene="yunB"
                     /locus_tag="ACGI5H_001132"
     CDS             28931..29629
                     /gene="yunB"
                     /locus_tag="ACGI5H_001132"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418439.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003674 - molecular_function [Evidence
                     IEA];
                     GO_process: GO:0030436 - asexual sporulation [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sporulation protein YunB"
                     /protein_id="HFG9696845.1"
                     /translation="MNRIVDRKTKNEFRKIIAIFLVILFLSVFIGSFIYIDKTLRPTI
                     TVLAETKALELANRSINKAVAEMVEGKINYEDLMDIQLDNNGKITMIQANTIMMNEIA
                     SAIALEIQDELKKDKTASSYIPIGTALGSPILAKYGPKLEVSIEPIGTVSVNFKTEFE
                     SSGINQTRHRIYLEAQTQVKVVIPLITSTKQIKAQIPICETIIVGDVPESYVNIPEKN
                     LGNVLPNTGKNTNK"
     gene            complement(29841..30848)
                     /locus_tag="ACGI5H_001133"
     CDS             complement(29841..30848)
                     /locus_tag="ACGI5H_001133"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888579.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SpoIVB peptidase S55 domain-containing protein"
                     /protein_id="HFG9696846.1"
                     /translation="MQLKNFHFKNNTLSKKTNLAKSKFTIVLTFLFLLYFFSNNLIYA
                     QNLQKNEPEYLIPIGNVLQIDAELKNIIVRNPGEASPFRLGDAIVKVNNAEVDGYSDF
                     ANTLNALPEEKQVSILLNRGGQLITMKTTKHILEKISFNNLLSGFATLTYINPDTSEF
                     GAVGHPISVGNARKIPIKTGSISTTKHLNIEKSYKGSVGCINAKRENIIGSFTENTDF
                     GIRGQINNFDISKLKKYKVASLDEVKLGKAQIILQDNFNKCKKYNIEIIDIENQKHPE
                     SKSFKIKITDKKLLAQTGGIVQGMSGTPIVQDNKIIGAVSHAIENDPAVGYGVFIKWM
                     L"
     gene            31076..31960
                     /locus_tag="ACGI5H_001134"
     CDS             31076..31960
                     /locus_tag="ACGI5H_001134"
                     /EC_number="3.5.1.28"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860957.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008745 - N-acetylmuramoyl-L-alanine
                     amidase activity [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase"
                     /protein_id="HFG9696847.1"
                     /translation="MKKYRLLVTCIIAMGIIIIGTSNPVSNFYKTTNLISSGNITNEK
                     ADKDENSNKNNKDKNEDKSNSKSNKDKSSEDKSSDNKNEIQKNKKLLICIDPGHQGKG
                     DSNLEPVAPGSSSKKARVSSGTEGIATKKPEYVLNLEASLVLKSILESKGYNVIMTRE
                     THDVNISNSERAILANDKKADMVVRIHADSLNNSSKTGASILIPEKDGKYTAPIYEES
                     NKCAEFIKQNMEQSGIQINGIVQRGDLTGFNWSKVPAVLVEMGFMSNYNEDQMMSNPD
                     YQRKMMQCIADGLDAYFK"
     gene            32162..33712
                     /locus_tag="ACGI5H_001135"
     CDS             32162..33712
                     /locus_tag="ACGI5H_001135"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007788866.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="HFG9696848.1"
                     /translation="MLVVENVSHGFGARTILENVSFRLRKGEHIALVGANGEGKSSFL
                     NIITKKLMPDAGNIKWSSRATVGYLDQHTVLSKGKTIREVLREAFKHMFDLEQEMIAM
                     YDKMGEASDDEMSKLLEETAEIQTILENSGFYMIDAKIQEVANGLGLGEIGLDKDVTD
                     LSGGQRTKVLLTKLLLENPTILILDEPTNYLDEEHITWLTKYLQEYENSFVLVSHDIE
                     FINNTCNVIYHMENGELNRYKGNYDEFVRLNDIKKRQEEQAYDKQVEERKRLEDFVAR
                     NKARVATRGMANSRQKQLDKMEILERPKEKIKPTFAFKDARAASKIIFETENLVLGYD
                     EALTKPLNFHLERGKKIALKGMNGIGKSTLLKTLLGIIKPFEGNVKLGDYLEVGYFEQ
                     ESSRENSNTPMDEVWSEFPGLTNFEVRQALAKCGLTNEHITSQMRVLSGGEAAKVRLC
                     KVMLKNINFLVLDEPTNHLDVEAKDELKKAIKEFKGTVLLVCHEPEFYSEIVDDVWNI
                     EDFTTKIV"
     gene            33741..34388
                     /locus_tag="ACGI5H_001136"
     CDS             33741..34388
                     /locus_tag="ACGI5H_001136"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437518.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR01906 family membrane protein"
                     /protein_id="HFG9696849.1"
                     /translation="MKKFLNVLFSICISIVIIVGVINFTVGFKQLYYFDIDYLNISEL
                     SGLSKDDIKLNYDYLIDYNLNKNVSEFKLPTLKSSPQGKIHFEEVRNIFQNINKLAKL
                     LLVVSLVGIILSVKNKNIKILKTTSITLIIMPLLLTVPILLNFEKSFIIFHKLLFRND
                     YWIFNPDLDPVINILPEEFFFHSGMMILILILLVSIVLFVMYKLCKSLSIKIFQC"
     gene            complement(34530..34790)
                     /locus_tag="ACGI5H_001137"
     CDS             complement(34530..34790)
                     /locus_tag="ACGI5H_001137"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437519.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine-rich small domain-containing protein"
                     /protein_id="HFG9696850.1"
                     /translation="MGENYKFFNHKDCEFFPCHKTNKPEEFNCLFCYCPLYALGENCG
                     GNFRYTDKGIKDCSSCILPHKKDNYNYIMSKFQDLVKITSKK"
     gene            35007..36290
                     /gene="hflX"
                     /locus_tag="ACGI5H_001138"
     CDS             35007..36290
                     /gene="hflX"
                     /locus_tag="ACGI5H_001138"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004453679.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005525 - GTP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GTPase HflX"
                     /protein_id="HFG9696851.1"
                     /translation="MKEIQEKALLVGLNLTTIVKKNDDIDTNESMEELKELTKAAGAE
                     VVGSLIQNKHSVDAAYYIGKGKVEEIRAYSDSLDATLVIFNDELSGAQIRNIENVVGR
                     KVIDRTTLILDIFAQRALSKEGKLQVELAQLKYRLPRLYGMGGEMSRTGAGIGTRGPG
                     EQKLEIDKRHILNKAADIRRELKEVKKNRETQRVKRLKSNIPIVALVGYTNAGKSTLL
                     NELIKTHKDYEQEKEVFVKDMLFATLDVTLRKALLPNKKEFLVVDTVGFVSKLPHDLV
                     EAFKATLEEVQYANLILHVIDATNTSYELQKSTTEGVLKELGVNDKKHILVYNKVDKL
                     ELDIYPKSQEDIVYISAKQGINMDKLLNMIEIALMENTYSVSLMLPYERGDIFSRIKD
                     KYNVENFEYGESGITLDADLDEEDFNIYREYILEK"
     gene            36298..36975
                     /locus_tag="ACGI5H_001139"
     CDS             36298..36975
                     /locus_tag="ACGI5H_001139"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888586.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005515 - protein binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="HEAT repeat domain-containing protein"
                     /protein_id="HFG9696852.1"
                     /translation="MDINWENIDNLEDYFITYLLYKESKTVSQISKIRNISSTEASEQ
                     LIQAKLKIKEMQKDDFEASKDILDKFLELDKIKRLDFMDSLDDEKMVYFKRKVFKRIL
                     VEKNAEDLIVLIWATGELKDDRFLKLLHQLTNHRHSDIRRITYSAIRKIESPSSREVL
                     QKGLYDKNAQTRQYCAKALSKLGDENSLKILQQLKDKNKNFEKEYVLRAYDEAIKSLE
                     NAKNLKK"
     gene            37061..37504
                     /locus_tag="ACGI5H_001140"
     CDS             37061..37504
                     /locus_tag="ACGI5H_001140"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418457.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
                     /protein_id="HFG9696853.1"
                     /translation="MIVRRCAGGVVFYANKVLIVKNDRGEWTLPKGKILGGGLPYESA
                     VQRVKVETGIDAKMIDVAGDTMYEFFSRSRQQEVCNAIMWYVMEACNTDCVLAPEFQE
                     GGFYKVKDALEMLSHHKEQALVEVSYKKFKELKKLVSEGDDVPAN"
     gene            37809..38453
                     /locus_tag="ACGI5H_001141"
     CDS             37809..38453
                     /locus_tag="ACGI5H_001141"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888588.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YigZ family protein"
                     /protein_id="HFG9696854.1"
                     /translation="MSNYRTLHEFGTDEITIEKSVFIGYAKPIKSEEEALEFINEIKK
                     KHKDATHNVWAYTVGKNMNIQRYSDDGEPQGTAGIPTLEVIKKEDLRDVAVVVTRYFG
                     GTKLGAGGLVRAYTKGAKLGLEAGKIIYKVMYQEVKVKIDYTQLGKVQNELMNLGYFI
                     KDTVYEDNVEIVVYSRLEDVEKLSEKMIDITSGTGKIVLGEEFYLSEQNGEILI"
     gene            complement(38539..38916)
                     /locus_tag="ACGI5H_001142"
     CDS             complement(38539..38916)
                     /locus_tag="ACGI5H_001142"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004453676.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TSUP family transporter"
                     /protein_id="HFG9696855.1"
                     /translation="MLFALIGFFAGIIGGMGMGGGTILIPALVLLAGIDTKIAQSVNL
                     LSSIPMTLIALAIHIKNKNVIFKLVIPIAVFGVLGAVFGSLLANYLSSDILKKIFGIF
                     LLLVGLFEVKKGFCAKSDKKPLN"
     gene            complement(38916..39302)
                     /locus_tag="ACGI5H_001143"
     CDS             complement(38916..39302)
                     /locus_tag="ACGI5H_001143"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418463.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sulfite exporter TauE/SafE family protein"
                     /protein_id="HFG9696856.1"
                     /translation="MKKTDDLKKKYFDFNLKNTIIGVFTGFINGVFGSGGGTLLVPIL
                     NDIVKVEEHKSHATALSIIIFLTTASSVLYVSKGTYDVNLTIKVAVGSILGGIIGAKL
                     LNKVTGKFLRISFGIIMIIAALRMVF"
     gene            39481..40236
                     /gene="nadE"
                     /locus_tag="ACGI5H_001144"
     CDS             39481..40236
                     /gene="nadE"
                     /locus_tag="ACGI5H_001144"
                     /EC_number="6.3.1.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888593.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0008795 - NAD+ synthase activity [Evidence
                     IEA];
                     GO_process: GO:0009435 - NAD biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(+) synthase"
                     /protein_id="HFG9696857.1"
                     /translation="MSNIKIQIDKTVEWLINKVNEANAKGLIVGVSGGIDSAVVANLI
                     KKAFPENSMGVIMSIKSNPQDREDALKVIEGCDIEYLDLDLIEPQSAILDMVVGNLKD
                     KHLYREEYLKMTDANLRARVRMSTIYTIANNLGYLVVGTDNAAEIHTGYFTKFGDGGV
                     DILPIANLTKGEVYEWAKELGVHEDLINKAPSAGLWEGQTDEDEMGTTYNMIDAVLEG
                     RLDEVPKRDQEIIERLHRLSEHKRKTPAQPPKF"
     gene            40319..41038
                     /locus_tag="ACGI5H_001145"
     CDS             40319..41038
                     /locus_tag="ACGI5H_001145"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418467.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YebC/PmpR family DNA-binding transcriptional
                     regulator"
                     /protein_id="HFG9696858.1"
                     /translation="MGRIGNIINRKGKQDAQRAKIFTKHARAIAVAAKEGGADPEYNA
                     ALKTAIEKAKADNMPNDNIDRAIAKGAGAGAGEDYETIVYEGYGPGGVAVIVETLTDN
                     KNRTAGNVRYYFDKNGGNLGTSGCVSFMFDKKGQILVGLGDGVSEEELMDVALEAGAE
                     DFITEEDGYEIITTPEDFSSVRDELKAKGYEFISADVKMIPQTTTVLTEESHLKMMNK
                     LVDMLEEDDDVQDIYHNWEVE"
     gene            complement(41205..42209)
                     /locus_tag="ACGI5H_001146"
     CDS             complement(41205..42209)
                     /locus_tag="ACGI5H_001146"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437541.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="substrate-binding domain-containing protein"
                     /protein_id="HFG9696859.1"
                     /translation="MATIKDIAKDCGLSSATVSYVLSGKGNERRIPLHTQELILNSAD
                     KLGYKRSTPIKHNNIKIAFYWQDEGFELASTNILQAINHIISLEHLNINIIIRPYKVG
                     HLCDDEYFFANNYYDGIVLTGINADDIEYLVKNKPKIPVVVVNREIPGFSSVSIDNEE
                     TGRIAALHAIQNGKNDIAVVFNPTSFTCMTLRGKSFLKTCKEHGIHLSDSIYYCSNKI
                     DSGYDIAQKMLAKNSLKKVIFCNHDVVALGMMNAFHESGIVIGEDIQIFAASNGPSRL
                     MARSIPPLTVIDLKMEETAERSLRMIIDTVTGRINGIQQQVIYPSIIYRQSSPAQNLL
                     "
     gene            42475..43371
                     /locus_tag="ACGI5H_001147"
     CDS             42475..43371
                     /locus_tag="ACGI5H_001147"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892786.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxymethylglutaryl-CoA lyase"
                     /protein_id="HFG9696860.1"
                     /translation="MSKVNIFEVGPRDGFQNLKEFLETDKKLKIIDGLIASGIKQLEI
                     SSFVSPKAIPQMKDAKEVATYCVEKYPDVKLYALVPNLYGAKVAWECGIRDISYVISL
                     SETHNKKNINRTHEESIDELKKIMNTYPDMNICIGMATVFGCPFEGLPKIEDAIRFAK
                     RLWENGIREINLADTIGIADPKQVRETISALVEALPECRWQVHIHDTRNMGMVNTLVA
                     IESGITTVQSTLGGLGGCPFAPGASGNTATEDLVYMLERMGYDTGVDFVKLLELSKYQ
                     KSFVNGVYSGHHVNIKSDSCNC"
     gene            43492..44754
                     /locus_tag="ACGI5H_001148"
     CDS             43492..44754
                     /locus_tag="ACGI5H_001148"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888596.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="SLC13 family permease"
                     /protein_id="HFG9696861.1"
                     /translation="MDIIALLLFLGVIIIAFVRKNNAGILALAIGVIAVRIFGMDDKE
                     LYGAISNSMFTTLVGITLLFAIVNSTGALKLVAEKIVAASGKRVWLIPIAVFIAGFVV
                     AGVGPGAIPALAIIPAMAVPVAITVGYNPVMLALIGECGLMAGRMTPITPEGQIITTV
                     AEGVGIENVMPTILACQTLSTIVFSIVLFIIFKGYKLKKPINVIDSKQIEKFNIKQII
                     SLISIVVMIAFIIIFDMNVGLAAFAVSAVLIFFNIADEGECIKSIPWSTIVMVLGVGA
                     MMTIVDAAGGIDLMSNALSSLMNSKTATPIMSISAGLMSMVSSALAVVYPTMMPMCVD
                     IAKAVGGVDPLALIAAVGVGGSLAGVSPLSTGGALILAAMGSSKKDFNKEEQNKVFVQ
                     LFIMSAVGLLVIAVVSILSFNAITHLMN"
     gene            44830..46023
                     /locus_tag="ACGI5H_001149"
     CDS             44830..46023
                     /locus_tag="ACGI5H_001149"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888598.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CaiB/BaiF CoA transferase family protein"
                     /protein_id="HFG9696862.1"
                     /translation="MKKGALSNIKVLDLTRVLAGPYCTMMLADFGADVIKIEMPRKGD
                     DTRGFGPFVNGESLYYANINRNKKGITLNLKSEEGKNIFLEMVKHADVVVENYRPGVM
                     EKLGLGYDELAKVNNQIIYGAVSGFGCYGPYSERPGYDIIAQAMGGLMSITGQEGGEP
                     TRVGNAMGDVLGGMNLTIGILTALNARKIIGKGQRVDVSLVDSVVSSLETGIQRYFDS
                     GQPELMGNRYASAYPYDSFKASDGSFVIGCGNDKLFEKLCKKVLFREDLLIDERFKTN
                     LNRCEHYKALKPEIEKWSVKHTIKEAVDLISEAGVPAAPIYNLDCVTTDEHIAKAREM
                     IVDISHPIIGNMKVNGNPVKLMTTKAKIDMPAPSLGESNEEIYNGWLGFDSDKIKDLK
                     ENGVI"
     gene            46652..47446
                     /locus_tag="ACGI5H_001150"
     CDS             46652..47446
                     /locus_tag="ACGI5H_001150"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003824 - catalytic activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="enoyl-CoA hydratase-related protein"
                     /protein_id="HFG9696863.1"
                     /translation="MESVMENLNNLKVEVKDKVCVITINRPKALNALNSDTLRELSQV
                     IDVVSENEAILGVIITGEGKVFVAGADIRQMQNYKSEEGRKYAGYAQGIFDKIEALEK
                     TVIAAVNGYALGGGCELAMSCDIRIASEKAIFGQPEVNLGVIPCFGGTQRLSRLVGTG
                     IAKELIFTGRQVNAEEAKSIGLINKVVPSDLLLEESMKMMNQIVEKAPIAIRYAKVVI
                     NKGIDMDLKNALELEKDVAGLTFATRDKQEGMNAFIEKRKPVFENK"
     gene            47541..48881
                     /locus_tag="ACGI5H_001151"
     CDS             47541..48881
                     /locus_tag="ACGI5H_001151"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437552.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GntP family permease"
                     /protein_id="HFG9696864.1"
                     /translation="MNTGVIISLVGIIIALSLLVVMVMKGINIFIIAIVCSSLVAITG
                     SLNVYDALKVDYMTGFVGFLQANFFIFLTGTLMGKIMEITGGAKSIAKMIVRWIGKDK
                     ALLSIPIACGILAYGGVSVFVVSFAVFPIALEIFKEADLPRRFIPAALTFGCSTFAMV
                     APGAPQIQNIVPASTLGTDIMAGAVNGFISCAVMFIVGSTILYKMVSKEKANGGHFIA
                     HESDIFDEAEATNSKRENGPNGVIALIPLIVSILIINVKVNGKAIVPIEVGVFIGALL
                     VYLLLNKYQDNTKIVGHVGDACKTTVVAICNTCAVVAFGSVVKSAVGFDFIVNAMTNI
                     PGPPIAGAAVGTTVIAGICGSASGGLGIAAPLLGPVFLAKGVSAAALTRTMAISSAAL
                     DSLPHNGYIVTVTNGLCKETHKDAYMPIFWVTVLTPFIGTIVAVLLFTMFPGLP"
     gene            49018..50250
                     /locus_tag="ACGI5H_001152"
     CDS             49018..50250
                     /locus_tag="ACGI5H_001152"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418473.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CaiB/BaiF CoA transferase family protein"
                     /protein_id="HFG9696865.1"
                     /translation="MLNKPLEGVKVIDLTYFVAGPGTSKILADWGADVIKVEPSFGDP
                     GRKTGATMTMPIDDYNNPFYSTYNSNKRGLSINLKSETGIEIMDKLLSEANVFVSSYR
                     TGALKRLGLDYESLSKKHPHLIWGQINGFGDFGPAKDNAGFDTVAFWARSGAMLDIAE
                     KDTSPINPPIAFGDATTSCSLSGGICAALYQQAKTGKGQKVMASLFGQAIWNASSLLA
                     STQFSDEYPKTRKNAISPVINSYRCKDGKWIFLSILEHERYFEALCRLFGREDLIKEE
                     KFASSVESKKNATELINILDGEFAKFTQNEMVEKLTAADIAHEKIQHVNDVVTDEQAI
                     ANNYIYEHTSKDGNKTMLASTPVKFGNIEVNMTCDAPLIGEHSDEILRELGYSDSDIE
                     TLIESGIVTMNKEACEIC"
     gene            50290..51432
                     /gene="acrC"
                     /locus_tag="ACGI5H_001153"
     CDS             50290..51432
                     /gene="acrC"
                     /locus_tag="ACGI5H_001153"
                     /EC_number="1.3.1.95"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437554.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003995 - acyl-CoA dehydrogenase activity
                     [Evidence IEA];
                     GO_function: GO:0016628 - oxidoreductase activity, acting
                     on the CH-CH group of donors, NAD or NADP as acceptor
                     [Evidence IEA];
                     GO_function: GO:0043958 - acryloyl-CoA reductase (NADH)
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="acryloyl-CoA reductase"
                     /protein_id="HFG9696866.1"
                     /translation="MDFRLTEAQLMLQRVAKEFAENEIAPIAAETDKTGIFPRELFSK
                     MAKIGFNGIGTPVEYSGSGGADIEKVIVVTEIAKKCAASAAILSIHTIYAQAILKFGT
                     EEQKKKYLPMMAEGGCVGAFALTEPNAGSDAARAATTAIIDEETDEYVLNGTKCFISG
                     GGQAESLIIFALTDPSKGIKGMSAIIVDKGTPGFSIGKIEEKMGIHGSETAELIFDNC
                     RVPKSNLLGKEGKGFNIAMTCLDGARIGVGAQAVGIAEGALEESIKYSKERVQFGKPI
                     SALQGIQWYIADMATMVESAKLLVYYAADLKARGEKHTKEAAMAKYNASRTAREVTNL
                     ALQIHGGYGYMKDYPLERMYRDAKITEIYEGTSEIHKVVISRAVLG"
     gene            51443..52237
                     /locus_tag="ACGI5H_001154"
     CDS             51443..52237
                     /locus_tag="ACGI5H_001154"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009899720.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="electron transfer flavoprotein subunit beta"
                     /protein_id="HFG9696867.1"
                     /translation="MNIVVCLKQVPDTNEVKINKETGTLIRDGVPSIINPDDRNALEE
                     ALKMKDELGAVIKVISMGPPQAKSALKEALAMGADEAYLISDRAFGGSDTWATSTIIA
                     AAIEKVGKYDVIFCGRQAIDGDTAQVGPEVAEFLGIPQVTYAKEVKVQDDKLLVTRYT
                     ETGDYLIEAKMPVLLTAIKELNNPRYPSVKGILEAYNNGDAKITVLTLADLDVDTTQI
                     GLKGSPTNVYKSFVPVKDKHNEIIEGINKKEKAEKLIEILFDLKLV"
     gene            52251..53270
                     /locus_tag="ACGI5H_001155"
     CDS             52251..53270
                     /locus_tag="ACGI5H_001155"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902164.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0009055 - electron transfer activity
                     [Evidence IEA];
                     GO_function: GO:0050660 - flavin adenine dinucleotide
                     binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="electron transfer flavoprotein subunit
                     alpha/FixB family protein"
                     /protein_id="HFG9696868.1"
                     /translation="MRAKVNQGINLNDYNGVWVIGEQREGKINPVTIELIGEGRKLAD
                     QLGKELAVVIAGYEVEKEVKELLHYSVDKVYYINDPLLKDFTTDGYAISIANLIERKK
                     PEVVLVGATSIGRDIAPRIAGKVGTGLTADCTKLEIDSTDNKLLQTRPAFGGNLMATI
                     VCPKNRPQMSTVRPGVMAKAVRNESETGILEVVTPELTEKMIRTRLVEILPQEKKSVN
                     LTDARIIVSGGRGLKRAEGFELIKELADKLGAEIGASRAAVDSGWIEHSHQVGQTGTT
                     VRPELYIACGISGAIQHLAGMSDSKYIVAINKDAKAPIFSICDYGIVGDLYEIIPEMI
                     ESLNR"
     gene            53369..54745
                     /locus_tag="ACGI5H_001156"
     CDS             53369..54745
                     /locus_tag="ACGI5H_001156"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-54 interaction domain-containing protein"
                     /protein_id="HFG9696869.1"
                     /translation="MKEQWYKDIFARVLSMTDDGFIVVNTSGVIIDINDKYCDFLGKE
                     RKDIIGQNIQSIIPNTKMLDVMKNKYCEEGAIHHYSGGNTKEKSVIVSRSYVENDNGE
                     VVAGVAQVKFRLQSFDVAKKLMSEYMELQYYKEQFKDNCGFDKLIGENRDFIELKKTG
                     VKASKTNFPVLLTGETGTGKEVFARAIHNNSSRSDKPMVSINCAAIPEELLESELFGY
                     DEGAFTGAKKGGKKGKFLVANNGTIFLDEIGDMPLTMQAKLLRVLQESEIEPVGGLKT
                     IKIDVRVISATRKNLSKMVEEGLFREDLYYRLNVINIHMMELKDRQDDILLLANYILN
                     KLNVEYKELKVLSDKVKNCFINYTWPGNIRELQNVIKSAYAVSDDMVIMMCDLPSKMD
                     NISRVAQCNVDSNCSIHEMVENYEKSLIIDVLRKYNWKCSKAAEVMGIHKSLLYKKIK
                     KYEIELNN"
     gene            complement(55077..55421)
                     /locus_tag="ACGI5H_001157"
     CDS             complement(55077..55421)
                     /locus_tag="ACGI5H_001157"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9696870.1"
                     /translation="MDQIKRLHELQQKSYLTKEEFEELKNNTYIERFELRDECDNSYI
                     YTFYTNDKCNDIKFIKSQFIVTLIKIGFLCECGGVFRQKKIVDEYDYGYNAIYKCDSC
                     GKELDKEVENYD"
BASE COUNT        21100 a         6578 c         9976 g        18070 t
ORIGIN      
        1 ataaaaaata ttattttata tttataaaca ttgacattct aattttgtag tgtaatcgta
       61 ttttttatta attcttacaa aatcaatgaa aataagtata tccattttaa agtacataaa
      121 tttaaaaatc cagaaaaata tacttaaatt atgtaagtaa aagaggggtt gaatcagttg
      181 aaaatgtaat attagtaaat agtacatcaa tcctatatac cctgtaagca actctatttt
      241 catgtactaa aaatgtacct attttattaa ctgaaaagaa taaattaaat gtaagtacat
      301 aagaagatag aaaaaattaa aaacaaaaaa tatttatata aataaatata aaaaatgata
      361 taatccctat taaaaaattt atagatgatg aagaaatatc aaaatcttat attataggaa
      421 gagacacttc tttgccaaaa tctatagaaa agcaatacca aatccaaaga gaataggcga
      481 agaaaaaaat aaaataaatt caagagtaat agaaaagttt tatagaataa agaactgata
      541 actctttata taacgaaaaa tagaatttta agagaaaatg atttaataaa tgatttaaca
      601 tggtgtttta gcaggtaaaa ataaatcacc agtaatgatt atagaaaaat tactttatga
      661 atctcaaaaa acttagttaa gagtaagaga tttgataaga taactaaagt tggggaaatg
      721 tgtttgatga gacaaaaaat tagtaaaata gtataatcta aataaggata ttttgttgat
      781 taaactacac taatagtaat attgtagggg gaaaagatga gagaagaatc gaactcttta
      841 agtttagacc atatagaaat tttctttgaa cttttatctc aaagtacaga agattatata
      901 tttttttggg atataaatag gaataaattt aaaatttctt cagcaatttt tgatgaattt
      961 aacttaagta aagagataga atctgatttg gtcaattgtt ggagtaaaat tgtttatccg
     1021 gatgatgttc aaatatggaa agatgatata caagaattac tacatggaaa aaaaggtgag
     1081 cacaatttag aatataggtt gattaataaa tataaagaaa tagtatggat ttcttgtaga
     1141 ggtaaagttt atgtgtcgga tgacccaaaa actatatttc tagtcgggag aataaagaat
     1201 attggtgaaa aaaataaatt tgattctatc acaggaacgt ggaatagaga acaatttgaa
     1261 catagaatga attatcttat aaaagagaaa atttataaaa atggtgctat gtttattatg
     1321 gatattgata attttaaaaa tataaatgaa aaatatggac attcttatgg tgacaaagta
     1381 ttgcgtgcaa ttgctactga agtattagaa tatcttccaa aagatgtaag attgtatagg
     1441 ttagatggag atgaatttgc atttttttac cctatgtgta ctaaagaaac tatagagaaa
     1501 atatatgaaa agatacagat gtatacaaat actcagcatg aaattgaatc aaataagtac
     1561 tattgcacag tgactgcagg cgttgctatg tatccagaag atggagataa ttatttagat
     1621 ttatttaaac atgctgatat tgcattggat atagcaaaaa ttagtggtaa aaatagaatt
     1681 aagttttttt cacaagagct ctatgaaaat aaactaaagg taatttcaat gcaacaaaaa
     1741 ctaagagagt gcgttgaaaa taattttaat gattttgagt tgttttttca accccaggta
     1801 aatgctgtta caaaagaggt aataggggca gaggtacttt taagatggca ttcgagtact
     1861 tatggagaag tatctcctgt tgaatttata ccaatactag aacagagtaa tttaattata
     1921 ccagttggga agtggattat aaaagaagct gtaaaacagt gtaaagaatg gcataaaata
     1981 aatccagact ttaaaatatc tgtaaatgta tcgtatattc agttaaagga agattttttt
     2041 agagatttta tagtagaatg tttagtagag tatcaattaa gacctgaatt tttaattttg
     2101 gaattaacag agaattgttg gataccagat ataaatttac taaatgataa atttattagt
     2161 ttaaagggta taggagtata tattgcaata gatgactttg gtacaggata ttcatcttta
     2221 aattacctta aagaactgtc tgttaatata ataaaaattg aaagaagttt tgttaagaat
     2281 attacatata atagttatga atatactttt cttgaatata ttattaaatt agctcatatt
     2341 ataaatttaa aagtttgtgt tgagggaata gagtcttatg aagagtatga tatagtaaaa
     2401 agcttaggtg tagatattat tcagggtttt ttatttggaa gacctgtaag tgcctctgaa
     2461 ttttataaat ttcagctatc aaagtgatgt atataaaatg agatatatag tatataaaaa
     2521 tagggcaaag tggaagtttt gaagtttatt aaaaatttac actttaccct attttgttat
     2581 gtcttctata aaggattaat atactacact aactattata tactttcact ccaaatttag
     2641 agattatttc actagctttt tggacatctt ccttagtggc atcaggaaca tcttttagtt
     2701 cataatcgat acctaaactt tcccatttgt gtattcccat agaatggtat ggtagcaatt
     2761 caaatctttc tacatttttc aatgtagcta caaattgacc tagtttttct aaattatcta
     2821 tatcatcagt aatgccagga actaaaacat gtcttatcca tacaggaata tttcttgatt
     2881 ctaagtgtct agcaagtttt aatgccttat ccataccaac accagtcaaa tcaatagatt
     2941 tttcctcaac catatgtttt aaatcaagta aaaccaaatc aatattatct aaaactgggt
     3001 ctatagtttc tatatctaca aatccagatg tatccaagca agtgtgtata tcattttctt
     3061 ttgctttttt aaataattca cttaaaaatt ctggttgaag agtggattca ccaccagagg
     3121 cagttatacc tccaccagaa aacttcataa aagaagtata cttaagagca tccgttatta
     3181 tttcatcaac tgtgtattct tttcctgatt taatatccca tgtatccctg ttatgacagt
     3241 atttgcatct aagaggacac ccctgaaaaa ataatatata tcttattcct ggtccatcta
     3301 cagtaccaaa cgtttctata gaatgtatct ttcccttaat catagagttc acctcacaat
     3361 atattttaat aaccttatca atagttataa tatttctcta aaaaaggcca tcttatacca
     3421 gaaataattc aaatataaga tagcctttta tttttatttt ttacacagta gtaatcttag
     3481 ttaaagtata aaaatttaaa gactaagcca ttttaccgtg gaatgttctg tttataacat
     3541 ctaattgttg ctctttagtt aattttatga agttaactgc atatccagat actcttatag
     3601 ttaattgtgg atattcttct ggatgttcca tagcatcttc taaagtagct ctatcaaata
     3661 catttacatt taagtgatga gcattttgag cgaagtatcc atccatcatt gcagaaagat
     3721 tgtttattct ttcagtcata tcttttccta aagcaccagg tactatagag aaagtattag
     3781 atataccatc ttgagcatgt tcatatggta atttagcaac tgaagataat gaagctaaag
     3841 caccattagt atctctacca tgcattgggt tagcaccagg agcaaatgga gcaccagctc
     3901 ttctaccatc tggtgtatta ccagttttct taccataaac aacatttgaa gttattgtaa
     3961 gtatagattg agttggataa gaatttctat aagttttatt ctttcttatt ttattcataa
     4021 agctttcaac taactctaca gctatactat caactctatc atcattattt ccgtattttg
     4081 gataatctcc ttctatttca aaatcaacag ctattccttg ttcatttcta atagttttaa
     4141 ccttagcatg ttttatagca gataatgagt ctgcacaaac tgataaccca gccataccac
     4201 aagccatagt tctaaatata tctctatcat gtaatgccat ttctaatgct tcataagaat
     4261 atttatcatg catataatgt attacattta aagtatttac atataatgtt gctaaccaat
     4321 cagtgaatgg ttcaaattta ctcataactt catcataatc taagtactca gaagttatag
     4381 gttcaaatct tggtccaact tgaacaccag atttctcatc tacaccacca tttatagcgt
     4441 ataataaagt tttagctaag ttaactctag ctccaaagaa ctgcatttgt ttaccaattc
     4501 tcattgcaga tacacaacaa gctataccat agtcatctcc ccagtatgct ctcattaaat
     4561 catcattttc atactgtact gaacttgtat ctatagatac tttagaacag aaatctttga
     4621 atccttgagg taatttagtt gaccatagaa ctgttaagtt tggttctgga gaaggtccta
     4681 atgtatatag agtatttaac attctaaatg agtttttagt aactaatgtt ctaccatcta
     4741 ttcccatacc tcctatacac tcagttaccc aagttgggtc tccagagaat aggttattgt
     4801 aatcaggagt tcttaggaac ttaaccattc ttaatttcat aacaaaatgg tccatatact
     4861 cttgtaattc ttcttctgtt acgattccag cttttaaatc tctttcaaag tatatatcta
     4921 agaaagtaga tgttctacct aaagacattg cagcaccatt ttggtcttta acagcaccta
     4981 aataaccaaa gtataaccat tgtacagctt cttttgagtt agttgctggt tttgatatat
     5041 caaatccata agattcagcc atttttttaa gttcatttaa agctgatatt tgctcagtta
     5101 tttcttctct taatctgata acttcctcat ccatgcaaga aacttctaat gatttctttt
     5161 gctcattttt atcttctatt aaagcatcaa caccgtatag agcaactctt ctgtagtcac
     5221 caattattct acctctacca taagcatctg gaagacctgt tattatacca gattttctag
     5281 cagctctcat ttctggagta taaacatcaa aaactccttg gttgtgtgtt tttctgtatt
     5341 tagtaaatat atcttttatt tctgggtcta attcatatcc aaaagcttca catgaatttt
     5401 caaccatctt tataccacca tatggcatga cagctctttt taaaggggca tccgtttgta
     5461 acccaactat tgtttctaat tctttatcta aatatcctgg agcatatgca gctattccag
     5521 aaacagtttt tgtatcaaca tctaaagtac caccattttc tctttctttt ttaaatagga
     5581 ccattgcttc gtcccataat tttttagtat tttcagtggc accagctaag aaagagtcat
     5641 ttccctcata tggagaatag tttaattgta taaactctct aacatttatt tctttagtcc
     5701 atcttcctgt tttaaatcct tgccatgcat tcattaagta tttcctcctt agatttaaat
     5761 gataaataat actattaaaa ttaattttta tatacttaat ttattttata tattttttta
     5821 aaaatatatt ttctaatata ataatagcat attattcgta tcctgtatac ataaaaaata
     5881 aaaaattgtc gctttaaagt ataaaacaga ttatatgtta ataatgtggt gaaattatac
     5941 ccatatataa ataaaataaa acaaataaat agctaattaa ggagaaaata ttttttattt
     6001 tttgtttagg ataaataaat tttattatgg aaaaaagaaa aagcatacat cttcacaaac
     6061 tgaatattta tttaataggg ggaggtgata gattgtttat cacagtggta ttatttttag
     6121 taggtttcct attaattact aaaggcgcag atatctttat aaattgtact gtagagatag
     6181 gtaaaaaaac gaatatatca gaaattatac ttggagctac tatagttagt tttgcaacaa
     6241 cattacctga gtttacagtg tctctacttg cttctattga tggtcatact actatgagtt
     6301 taggaaatgc agttggttct ataatatgta atacagggtt agcattaggg ttggttgttt
     6361 ttataagtcc atttaatgta gataaaaaaa tgtttttttc taagtcttta ctattaatag
     6421 tatccgttat agttttaatt ttattgagtt tagatggagt tataacaaga ggtgattcat
     6481 tattacttat aataatatta atcttttata tggttaataa ttatagaagt gtcgttggaa
     6541 aatctgatac taaaaataga aatattaaaa ataacactat taaagacata tctactaaaa
     6601 aagggaaaaa ttatagaggt ttttccgtat tagaaattgt aaaaatacta ttactttttg
     6661 ctacaggatt gataatgatg ataataggtt cacaaatcct tatagagagt ggagtaataa
     6721 tagctagttt tttaaatata cctcaaggta tagtaagttt aactataata gcacttggaa
     6781 cttctctgcc agagatagtt tcgtcgatta ctgctataag aaaaaatcat catgaaatat
     6841 cagtaggaaa tattttgggt gcaaacatat tgaatatagt atcagtaata gctgtatcag
     6901 caataccaaa taacatacca atactatctc aaaatagaca attggatata ccattcatga
     6961 tattattatt attaatagta ataataccaa cacttaaatc taataaactt agtagaatac
     7021 aaggtatatt gatgttattc acatattttc tgtacatatc aattttgtat ttcatgtata
     7081 ttatttaact atactgttta aaatattaat tgcagaatat cctaaaaaag tatataatgg
     7141 ataggttaag attaattgat aacggagagg aataatatat gaatataaca aagtttgaag
     7201 atttaccaat aagtgaggga ataaaaaaag ctatagctga aatggggttt gaagaaccat
     7261 ctcctataca agcacagtct atacctgcga ttttgtcagg taaagacgtt ataggacaag
     7321 ctcaaactgg tacgggaaaa acagctgctt ttagtatccc tatactagaa acaatagacc
     7381 caaataatag aagtttacaa gctgtagtgc tttgtccaac aagagaactg gcaatacaag
     7441 tatcaacaga aataagaaag ttagctaagt attcgcacgg aataaagaca ttacctatat
     7501 atggtggtca gccaatagat agacaaataa aatctctaaa gagtggtgtg caagttgtaa
     7561 taggtacacc aggacgtaca atagaccata tcaatcgtaa aacattaaag atggataatg
     7621 taaaaatgat tatattagat gaagcagatg aaatgctaga tatgggattt agagaagata
     7681 tagaaatgat tttaagtaag attccagaag aaagacaaac aactttcttt tcagctacta
     7741 tgccaagagg aattttggaa ttaactaaga gatatcaaaa agacccagag catataaaag
     7801 ttgttagaaa agaacttaca gtttcaaata caaagcaata ctatatagaa actaggtcat
     7861 caaataaatt agaagtatta tgtagattag tagatgtata tgaccctaaa ctatctgttg
     7921 ttttctgtaa tactaagaga aaagcagacg aattggtagg agatttacaa gcaagaggat
     7981 attttgcaga tgcattacat ggtgacttaa aacagactca aagagatata gtaatggata
     8041 agtttagaaa tggtacaata gatatacttg ttgctactga tgttgcagct agaggtatag
     8101 atgttgatga tgttgaatgt gtattcaact atgacttacc acaagatgaa gaatattacg
     8161 ttcatagaat tggtagaact ggtcgtgctg gtagagaagg tatgtcattt acttttgtat
     8221 ttggaaaaga aatgagaaag atgaaagata tagaaagata tactaaatct aaactaataa
     8281 agcataatat accaacaata actgatgttg aagagaaaaa agtaggtact ttctttgcac
     8341 aagttaaaca aactatagaa gaaggtcact taactaaaca attacaatgg ttagaaggtt
     8401 tctgtaatga tgaagattat gcaatggttg atatagctgc tgcacttgta aaactatctc
     8461 taggtgaaga aatgaaagaa gaaataatag aagaaaaacc tagaagagag cgtggagata
     8521 gaaaaggtgg tactggagct aaagatggta tgattagatt atttatcaat attggtagaa
     8581 atcaaagagt acaagcaaaa gatatagttg gtgccatagc tggagaagtt ggaataccag
     8641 gtaaagtagt aggtactata gatatatatg ataagtatac ttttgttgaa atacctaaaa
     8701 aagatgcaaa aacagtaatt gaaaagatga aagatattaa gataaaaggt aataagatta
     8761 atatagaaaa agcaaataag aagaaaaaat aacgtatagt atacaaaact ataattagaa
     8821 aatatataaa ataatatatt ggatatttaa aaagcctgat gtgttttcaa aacagatagt
     8881 agataatctg taagagttaa cagcataagg cttttcttgt tttatatgat gttataattt
     8941 tccagattgt tgtgaaaaat gtatattagt tccttttttt caaatctgat ttgaaaaaga
     9001 gaatattaat tatctatata gtttagatta taataaaaaa tgtaagataa caaaggggag
     9061 aaaaagatgt caatgactta tatggaccct agggtttttt tgattttaga aatggtgtta
     9121 gaagaagaca caaatactct agaacaattt tcaaatgttt tgggtgttag tactaggact
     9181 atcagaaact atataaacca gattaatcga gaattaaaag gtggtattgc taaaatagtt
     9241 aaaaatgaaa aaggtacata tagtataaga attgaggatg aaagtaaatt aattgagatt
     9301 gtaaatttta atagaggaaa gctatcaaat tttataaatt taaattcacc tgatgaaaga
     9361 ataaattatg ttcttgatat tttaactatg accaacaatc caattaccat agatgatttg
     9421 gctgaagaga tatgtatagg aagaacaaca ttaataaagg atttaaaaaa agcagacaga
     9481 attttagctg aatatgattt agaattaaaa aggaagccaa atataggtat gattttagtt
     9541 ggtgaagaaa tggatataag attattaatc cttgatagat tgtatgaaaa ttatattgat
     9601 gtcttggaaa acgttaatca gataaattta gttaaagatt atgatattga atgtcttaga
     9661 gatgaattaa aaaagttatt taaaaaagaa gaactctaca taacagaaca ggtcttgaga
     9721 gatgttgaaa gatatataat catgtctgtc ttaagaaatc taaatgggta caaatttgaa
     9781 aagatagata agagatttga agtgataaga tgttcagatg aatatacttt aggattaaag
     9841 ctcaaagctt tattggaaaa gatatttaat atagttttaa atgaaaaaga aaccatattt
     9901 ttgacaatgc cattaatagg tagaaaagct cctagtacaa aattagcact tagcagtata
     9961 aagataaatg atagcgtaaa ggaagttgta gatgaagtaa ctagtttttt attagagacc
    10021 tcagggattg attttaaaga agataaaaag cttatagaaa atttggaata tcacttgtat
    10081 tttgcactta atagaatgag attcaacata agggtaaaaa atcctctttt acaagaaata
    10141 aaggaaagat atacatttcc atatagtgtt gcaaagatag ctgcaatgat aattgaggaa
    10201 aagtttgact tgaaaatatg tgaccacgaa ataggatata tagcattaca ttttggaagt
    10261 tattttgaaa aaaattcaag aaaagttcta aatgtaaata gggtagctgt tgtttgtgga
    10321 acaggtcttg ggactgcaca acttattaga ataaagatag gaaaaatact tggagaaagt
    10381 gtagaagtaa atactttttc tgatatagaa gctaaagcta atttagattt attaaagtat
    10441 tatgatttag tatttacaac agtagatttc aaaacagact tagatgttcc aatttttaga
    10501 gtaaatgcgt tatttaatga agaaagtata aagaaagaga tagaaaatgc aatacttttg
    10561 aaaaatagta taaatcttaa gtctataaaa aagattgaaa aaaatatccc ttttataggt
    10621 aaattaattg aagaggataa gttctttata ttgaataaga gtacgtttat ggaaaattta
    10681 gaagatatgt tagaaaaatt agttcataaa ggaattattg atatagagtt caaaaaaaag
    10741 gtattaaaaa gagaaaagaa atcttcaaca gcattagata attatatagc attgcctcac
    10801 tcagttaata ctaatgggga aaatctttat ctggcatttg gaatattaga aaaaccagtg
    10861 atttgggata caaaggaaat tagaataata atattgatga taattccaga taagaatgta
    10921 gatagtacag acctgataat aaaaagttat gaagaagtac ttgaagtagg gagagataaa
    10981 aagatggtag aagaacttgc taaggcaaaa tcatttgatg aattttataa aataattacc
    11041 aagaggaggt aataatatgg acccagtaat ttttattata gcatcactta ttacagtgta
    11101 tttattaaat atttttcttg gatacttaca gcttaaagat tttaataaaa attatattga
    11161 actaaaaaga aaaggaagag tggcaattgg cagaaaaaaa ggaagaattt catcgggtac
    11221 aattgtgttg atacttataa atgatgatgg tgtgattgtc gagactagaa aaatgcaagg
    11281 tgttacagta ttggcaagag taaagtcatt tgaaggtttg gtaggaaaga acttagagta
    11341 tatagaaaaa tcagatttaa ctgtttacaa taaactactt aaaaaagcaa tactagatgc
    11401 agtcaaacag tacataacat ttgagaaaaa taaatgtgaa gatacaaata atctgagtac
    11461 tgatgaagag tgtaggatgg aagtagttta aaaaaatata tttataagga ggagttaata
    11521 tgacgcaatt ttttcaagta ttagcaagtg gtgcagatag ttttatgaat ttatttaggg
    11581 caggtgggca acaatttgta ggttttgtaa cagatatagt accactttta gtagcattat
    11641 tagttacaat gaatgcaatt atcaacttta ttggtacaga tagagtcgag agacttgcaa
    11701 aaaaatgttc tgcaaatata tttactagat atttgatatt accagtcctt ggtacatttg
    11761 tatttgcaaa cccaatgaca ctatcattag gaagattctt gccagaaaag tttaaaccta
    11821 gttactttgc agcagcaagc ttttcatgcc atacaatgaa tggattattc ccacatatca
    11881 atccaggtga actatttata tatctaggaa ttgcaaatgg tataacaact ttgggattct
    11941 caacagcaga tttagcagtt agatatttgt tagtgggtat agttgcaaac tttattaaag
    12001 gtgtagttac tgactataca acaaaatttg tagagaaaca acaaggaata gcattaaatt
    12061 cagatataaa gattggataa ttactttaag gtataaataa atttttcaaa taaaaagata
    12121 gtgtatagag gaggataaat tatatggcat ttaacaaagt taaaatagta aaaggttctg
    12181 gaggatgggg tggaccattg ataatagaac caacagaaaa gaagaataag gtagtatatg
    12241 tgactggggg agcaaagcca gaaactgcag taaaaatagc tgaacttaca ggatgtgagt
    12301 taatagatgg attttcacag ggtgttaaag atgatgaaat cgcatgtgta ataataaatt
    12361 gtggtggaac attgagatgt ggtatatatc ctcaaaagaa aataccgact ataaatataa
    12421 tgaaaacagg aaaaagtgga ccattagcaa tgtttataaa agaagatata tatgtttcag
    12481 gggtaaaacc aacaaatgta gagcagttat aattgaggta gtaggaggga agaaatatgg
    12541 cttatgatac taaaaagaag ataagtgagc agagtcaagg aattgttgca aaaataggta
    12601 tagcactagg aaatgtgaca agtactcttt ttcaagctgg tagggatact atagatacat
    12661 taatacatac tatactgcct tttatggctt tcgttgcagt cctaataggt ataataaatc
    12721 aatcaggtat aggaaattgg gtagccaatt tacttactcc attaatcgga aatgttggag
    12781 gtttagttgt cttatcaata atatgttcat ttccgttgtt gtctccgttt cttggaccag
    12841 gagctgttat agctcagata gtgggagtat tggttggtac agaaatagga aaaggaaata
    12901 ttccaccaag tttagcatta ccagcattgt ttgcaataaa ctcacaagca gcttgtgact
    12961 ttataccagt aggtcttggt cttgcagaag ctgaacctga tacagttcaa gtaggagttc
    13021 cgtcagtttt atattctaga tttttaacag gtgcaccaac tgttctatta gcatggttag
    13081 caagctttgg gttatataaa tagaagaata ctttataaat aattagagag aggttcagtt
    13141 gatatggaat taatatacag tactcaaata aataaaatag gagataatgc aaatgaattt
    13201 ttacaacata atatgtttgt aactttcaaa gataatgctc ctcaagagtt agaaaattac
    13261 tgttatatac attctgaaaa taatttagta aaagaaatac ttacggatga tgtgctatca
    13321 ataaataatg ttgattacaa aattacttct gttggtgagt tagtaaacca aaatctttca
    13381 gaattaggtc atataacatt taagtttaca ggtgaaaaag atggagcaat tggaggaacc
    13441 ttatatcttg aagaaaaaga aatagcacct attggcgtag gtactatact aaaaataatt
    13501 agaaaataaa atttaaaacg aatctaatca tattataagt aaattataga taaaagtcaa
    13561 tttaactaat caagttaact tttaatgtga taaaaaaggg gaaatgaaaa tgagaaaagt
    13621 ggctttagtc gttggaggag gaagaagttt aggtgaatat ttatctaaac atttagctaa
    13681 agtaggttat gatgttgcta ttgcagattt aaatgaagac aacgtaaaaa aagtagctga
    13741 agaaataaaa actgaatttg gttgtaaatc tgtaggatat agttgtaatg ccatagatga
    13801 aagacaggtt ataagtactg tcaaagctat tgaaaatgat tttgatagaa tagatttatt
    13861 agtgtacaat gcaggagtgg ctgtaagtaa aaaaataact gattttggat acaaagattt
    13921 taaatttatt gtagacgtaa atttaaatgg gtactttcta tttgcaagag aagtatctaa
    13981 agtcatgata gcaaaaggta ttgagggtag aataatacag ataaattcaa aatcaggtag
    14041 agtgggaagc aagcataatt caggatattc agcaggtaaa tttgctggag taggacttac
    14101 tcaaagttta gcgctagatt tggcagaaca taagataact gtaaatgcac tgatgctcgg
    14161 taatttactt gattctgata tgtttgaaag tttaattcct caatatgcag taaaattggg
    14221 aatacctgaa tcagaagtca agcaagttta tatagataaa gtacctttaa aaagagggtg
    14281 tagatttata gatgttgcaa atatgcttac attttatgct tcaaaggaag ctgaatactg
    14341 cactggtcaa tctataaata ttactggtgg acaagttatg taaggttttt atggagtgtc
    14401 tcaagatgaa ctctttagtt catgaggcac ttttttgtat aaaattaaat atattttcag
    14461 catttaaaca atgaaaaaga ggtttatctt tattttgaga tagcctcatt tttgtaatta
    14521 aaaaacatag tgtttaagta aacatataag attgttagtt ttttaaaaga gaatttttta
    14581 ataatattat atttatgaag tatttttaaa cttattttga taaaatatag ctatgtttta
    14641 tatactgtag ttttgaacat agaaagttta ataaattata gtatatatgt taatttttaa
    14701 taaggtaaga aagtagaaag aaggatattt tatggatata ataaaaaaat taagtcatgg
    14761 gtgtacatta gattgtcatg actgttgtaa attcaatgtt tatactaaag gaaataatgt
    14821 agtaaaaatt gaaggagata aaaatcatcc ttatacaaaa ggttttatat gcaaaaaagg
    14881 gatggcccat ttagatagat taaatcataa agatagaata aagactccta tgcttaaagt
    14941 tgatggagta tggaaagaga tttcttttga taaagctata gaaataatgg cagaaaagct
    15001 tacatactat aaagaaaagt atacatcaaa gtctgtcatg cattatgacc aatatggaag
    15061 tgggtctgtg ctaaaataca taggagatat attttttaat ttttatggag gtgttagcag
    15121 acataaaggt ggtccctgtt ggagtgcagg gatgcatgct caaaaatatg attttggagt
    15181 agctaagagt catgctatag aagatatgtt aaatagtaaa agtatatttg tgtggggaaa
    15241 aaatccagca tatactacaa ttcatactat gcaaataatt aaaaaagcta aagaaaaagg
    15301 gataaagata gtagtgattg accccatata tacaaaaaca gctcaaatag cagataagta
    15361 tgtacaagta aatcctggaa cagatggagc tttagctata gctatggcaa aaattatagt
    15421 agaagataaa ttatatgatg aagaatatat aaactcgtat gttattggtt ttgaagaata
    15481 taaaaaatat ttatcttcat tggaattaag ttttttaatt gatgaatgtg gtgttaaaga
    15541 gaatgatata agagagttag tggatttata tactaacaaa tattcaagta taaatgttgg
    15601 atatgggctt caaaaatata aaaatggtgg aaacacaata agagcaatag atgctttagg
    15661 tgctataact ggtcaaatag gatttagtgg tggaggggta aactatgcta ataaagttta
    15721 tccgagtgtt ataaattctg acccttacaa tagccaatca tatggtgaag atagggagtt
    15781 ttatgtaagt aatatcagta aatttataga agaatcttta aaaaatacat caaataaagt
    15841 aaattatgca tcagatgaac ttgatatgac atcaaataaa gtaaattatg tatcagatga
    15901 acttgatata acatcaaata aaacagatta tatatcaaat gaattgtata atttatctaa
    15961 taagtcaatc aaaggtaata ttcctataaa gatggctgta ataactaaaa gtaatatgct
    16021 gaatcaactg ccagatttag tagaattgga gagggtgttt tcaaaaattg aatttaaagt
    16081 atgttttgat atgtttataa ctgatacagc tactttatgt gacatgttta taccgtgtac
    16141 aaatacacta gagagtgaag atataattta tagctcaatg accaatccat atataaccta
    16201 taatgaaaga gctgtaaagc cagcacataa attgatggat gaatattact tctttatgga
    16261 gctagctaaa aagatgggat taaatgatta tccttttgta gaaaagagaa cttatttaga
    16321 aaaagtgatt gaaccactta agcgttttga caaaaatctg gatatagaaa aacttaaaaa
    16381 caattacttt actatacata accctgttgc ttgggaagat aagaagtttg agactccatc
    16441 tggaaaatac gagctttatt cagaaagtat aaaaaacttg ggaataagtc caacacctgt
    16501 atatataagc aataaatata aagaaataga agataaaaat atttctttta gattattaac
    16561 taatcatcat gcagatactt tatttagtca gcattttatg gacaaaaaat ctatagctca
    16621 agcatatata aatcggagaa tggctaaaaa agtaggtatt gaggacaaag atattgtgat
    16681 attgaggtca aaaaaagcaa aaataaatgt acaaataaat atagatgatg gagtaggtaa
    16741 ttatatagta aaaatgtatg ttggttggtg gaagaaacat ggaaatccta atagtttaac
    16801 agacactggt atatcagatt ttgggggtca ggtaacatat aatgaaagta tggtagaaat
    16861 aatacgacaa aactagttaa atttcattga aggaataaaa atataattat agaattgatt
    16921 aaaagttact atttttacaa aactattgaa ggagggattt ttgatggtaa attattcctt
    16981 agaacataag aatctataca tagaatttat gtgctcagaa ctagaccacc atgtagccaa
    17041 tgaaataagg gaagaaatag ataacttatt aagtgtaaat caagtaaaaa atgttgtatt
    17101 taattttgaa aatattaatt ttatggattc ttcaggtata ggcgtcatca taggtagata
    17161 taaaaagatt tctaatgaag ggggacgagt ttcagtaatt aatataagtt cacgagttaa
    17221 gaagattttt gatttatctg ggttaaataa aattattggc atttatgata cgtatgaaga
    17281 agctctaagt tctttgtagg gaggagtatg tgatgaataa tattatggaa gttaaatttt
    17341 cggcaatatc tgaaaatgaa agtttagcaa gagttatagt agcatccttt gcagctaagt
    17401 tagacccaac agtagatgag ttagtagata taaaaactgc tgtctctgag gctgttacga
    17461 atgctataat acatggatat gaagaagaca gttctaagtt tgttttctta agatgtgaga
    17521 tagaaggaaa tactataaag attatagttg aagatgaagg gtatggaata gaaaatgtgg
    17581 agaaggcaat ggaaccactt tatacatcaa aaccagaact tgatagatca ggaatgggat
    17641 tcacagtaat gaaaagcttt atggacgatg tagaggtaag ttctgtaaaa gataatggga
    17701 ctagaattga aatgactaaa aaaataaatg tgcctaaata aagtccaaaa gtgaggtttt
    17761 attatggaag taactgttgc cagagaagaa aaaaaacctc ttcttagtca tgaagagact
    17821 ctagaactta ttgaaaaagt tcaaaatgga gatgaagagg caaaagaaat attaatatca
    17881 agcaatttag gtctagttag gagcgttgta tctagatttt taaatatagg atatgataga
    17941 gaagatttat ttcagttagg ttctataggc ttaataaaat caatatataa atttgaccca
    18001 aaatttaatg taaaattctc tacttatgca gtaccaatga ttttaggtga aataaagaga
    18061 tacttaagag atgatggtat gataaaagta tcaaggtcgt taaagcaaat agctataaag
    18121 gcaaagatgg aaagtgaagc tttaactaaa aaattaggta gagagccgag tatagaagaa
    18181 ttagctaaag caatagatgt agaaaaagaa gatttagtaa tggctatgga agctaatttc
    18241 aatgttgagt atttgcaagg agttattcat gaagaggaag gttctccaat atgccttatt
    18301 gataaaataa gcatgaaagg agaaagtgaa gaagaaaaag tagtggataa catattgtta
    18361 aaagacatac ttggaagact ggataagaga gagcgtcaaa taatagttct cagatacttt
    18421 gaagacatga ctcaaagtga aataggagag atgctcaata tatcacaagt tcaagtatct
    18481 aggatagaga agaaagtatt gtctaagtta aaagaatata tatcgtgata atacttatga
    18541 tatgtagaat aataaaatat aataaatata ttactaaaat aaaatgtaat aactttttat
    18601 gttaagtttt taaattatta aaagatatta aaataataaa aagcattaaa aaagtaaaaa
    18661 tataaaaaca aggtgtcttt atggaaaaat agattttttc tttattaggc atctttttta
    18721 ttttttgacc aaactttaga tagtcaaaat aaataatagg tttatttttt taaaattaac
    18781 aaataatact ttagagaggt gtttagtatg gataaaaatt ataaaaaata tgtagaccaa
    18841 ataagcccaa aacctacata tttaaaaaac tatacacttg catttattgt aggtggaatt
    18901 atttgtatga tagggcaagc aataaatgat ttgtatatga aagttggagg tcttgataaa
    18961 ctaggtgcta gttctgcaac atcaataaca ttaatattta taggggcatt tttaactgga
    19021 ttaggagttt acgacctaat aggaaaaaga gctggagctg gttctataat tccaataaca
    19081 ggttttgcta actcaatagt atctccagca atggagtata aaagagaagg ctatgtatta
    19141 ggtgtaggtg caaacttatt taaaattgca ggaccagttt tagtttatgg gataggttct
    19201 tctattttat gtggaattat ttattatatt tttaagatgt tttagatgat ttttatttaa
    19261 tttaaatttt attaattatg aagaaggtat aaaatctgaa aatagctact aaagtaacta
    19321 attgaaaaat aattctgcag atttaattaa tatttttaat taatattaaa aatttgaata
    19381 gtaaaatgca aaattaaaaa ggtgtgaaaa tatgaaaaat aaaagaattg gaaaaagaac
    19441 agtcaagtta gaaaataaac caaccataat atcaactgga actatagtag gtcctaagga
    19501 aggtgaagga ccactaaagg actattttga tatgattatg actgacgatt tatatggtga
    19561 aaagacttgg gaattagctg aaagtaaaat ggtagagact gcatctcaac aagctatcca
    19621 aaaggcaggt aaaaaattgt cagatgtaaa ttatatgcta ggtggcgatt taataaatca
    19681 aatagttcca gcatcctttg cagcaagaga actggctatt ccatttttag gtatatatgg
    19741 agcttgttct acaatggcag aaggtctttg tataggttct atgcttatag atggtggttt
    19801 tgctgattta gtactgtcag gtacatcaag tcactattgt acagcagaaa gacaatttag
    19861 attcccactt gaacttggaa atcaaaaacc aatgacagcc cagtggacag ttacaggagc
    19921 aggaagtgta ttattagctc ctaatggaga cggtccaaaa gtaaagtatg ttactgttgg
    19981 taaagtaata gatgagggta ttgatgatgg taataatatg ggaccagcta tggctccagc
    20041 agcaatagat actatctact cttactttga agatactaat gatgacccaa atagctttga
    20101 tataattgct actggagatt taggtactct tggaaaacag atagcagaag actttctaaa
    20161 agaaaaaggt gtagatatat caaaagttta tactgactgt ggtatagaga tgtttaacct
    20221 taaagaacaa gatgtccact gtggtggaag tggatgtggg tgttcagcta cagtgtttgc
    20281 aggatatata tatgataagt tgagaaaaaa agaatttaac aaagtaatgc ttgtatcaac
    20341 aggagcacta ctttcaccga caagtacact acaaaagcag acaataccat gtgttgcaca
    20401 tgcagtagta atagtaaatg agtaggaagt gatataatat gttaatggac tatgtaagag
    20461 tatttattgt aggtggaatt atatgtttaa tagcccaagt aatgatggat tatttcaaaa
    20521 tgcaaactcc atatgttatg gtaacgtatg taacaactgg tgtagtttta acttttctag
    20581 gactttatga gccattagtt aagtttgcag cagcaggtgc aacagttcct ataataggat
    20641 ttggatattc acttgctaca ggagtaataa aatcaattca aagtgatggt tttttaggta
    20701 tttttttagg aggtacaact gctacagctg gtggaatagc agcagctata ttctttggat
    20761 atattatgtc agtagtattt actccaaaag caaaaccata aatctttatt aaaagaataa
    20821 taagtttttg aaataataac tttttataaa gcaggtggat atcttttaga ttccacctgt
    20881 tttttatata aagaagcgtt tacataattg aagttgacaa ttatttacaa catagtgtag
    20941 tattatatta tcaaaataaa atgaagtgaa gtaggggata aagatggtaa ctattaaaga
    21001 tattgcaagg aatctaggta tcagttattc aactgtttct aggtgcttaa acaataatcc
    21061 taatgtatct gaaaaaacaa aaaagaaagt ggtagaagag gcaaatagac tagggttcca
    21121 ttttaatgta aatgcaagaa atttagcaaa aaaagaaact aacaggatag gggtaatctt
    21181 ttcaaataat tttaatcatc aagatactag aaagtttttt agtgatataa tggatagttc
    21241 tataaattct attgagacta ataaatacga ttttataata cagcctaata ataacattag
    21301 tggtgatagt aatgtatata aaatggtaaa tggacaaatg gttgacggat tagtaattgt
    21361 gtctcaatca ataaaaaaag aagagtatga ttttttaaaa gacaataatt ttccacatgt
    21421 atttatatat tttaaaccat cttttatagg agaagtagat aatttctttt gggacgataa
    21481 cgtgtatgga ggttatatag ctaccaagca tttaattgac catggtcata aagatataat
    21541 aacagtaact tcagatgata agagttcaaa aatgcatgaa gatagaacca agggatattt
    21601 gaatgctatg gaagaagcaa atttaaagac agaagtcatt aaatctaaaa tggattttga
    21661 atctcaagtt gaatttttag aaaaatacat tgataaaata aaaaaagctt cagctatatt
    21721 tgtacaacaa gatgtaccag cgatttctat aatacaagag ttaaaaacta cttatggtat
    21781 aaatgtacca gaagatattt ccataatagg gtataataat attgaattaa tatcatattt
    21841 taggtcgcat ttatcaacaa tagatgaccc aagagagcaa gttataaaaa atggagtaga
    21901 tagtttagta aatataataa ataaaaagag tacagaacac attccaagaa aattatatcc
    21961 aaggttaata atacgaaata gcgttaaaag aataaagtag taagctttta agtatcaaac
    22021 gtttattaaa aatattatag attatgtgaa gttttttaac aaataatata aataaaaatt
    22081 aaaaggagta ggtgtatata agtacattgt actcctttat ttattgagat agtttttata
    22141 atatgaatga ataattttat tcaattattt gaaaatccgt tattttaaca atataaatta
    22201 ataaattatt tgtattttat atcatgaatc tataatattt ttttgattca taactaaaag
    22261 tatataaaaa tgatgaataa atatatatta tacattatca atgataggtt atataataaa
    22321 atcactaaca attatattat aagaaaatta taaaaattac aaggaggtat agaaatgaaa
    22381 gaaaaagcag ggattagaaa tgccataata gcagccttta taatcacaat attggcagaa
    22441 ttaattggac ctatttcatt taaagttatg ggaattaatg taactttact tagtatacta
    22501 tgggctatat tcataggaat ggctgtttct cctcatttat tagggagagt tataccagcc
    22561 ttaaaaaagt ttatagggga taatgaaata aatgtatctc catatttatt atctttgaca
    22621 ctatatccat tagggataat gtttggaatt aatgcagggc ctaaagttgg tatattactt
    22681 caagcaggac cagcactttt attacaagaa tttggtcata tgggtacaat gttgatagca
    22741 ttacctgttg gagtagcatt aggtcttgga agaagtgcat taggtggtac tttttcatta
    22801 tgtcgtgaca cagcactagg aattattgga gataagtatg gattaaactc accagaaggt
    22861 ataggaacac taggaactta cataagtggt agtatatttg gaacattatt attttcattt
    22921 ttagcaccag tgggtgtact tttaggattt catccatatg ctttagcaat ggcatcagga
    22981 atgggtagtg gttcaatgat gggagctgca acagcatcat taatgaatac agttccacaa
    23041 atgtcagagc agattttagc atattcagct actagtggat tgattacagc tgttactgga
    23101 atatatatag aattattctt atctttacca gtagccaact actattatag caaagtagct
    23161 ccagttattg aaagatttag aggaagaaaa acaagaagaa caagtaataa attgtaaagg
    23221 aggatatata tatggaaaaa acttttaaga ctattatgga gcagataaaa atagtattgt
    23281 ttatatatat tattatttgc tttggacaaa tgatagcact taagactcag gctcaagatt
    23341 tgttgattgg aagtgtatct ggatttttgt tggtgataat tgctattata ataaagaatt
    23401 ttgttaaaaa acctaattta ccaggttttg catgggctac attagttgca tttgttttat
    23461 cgcttccaat atctccagtg ggggatatca tagcaacaaa tgtagggaaa atcaatttta
    23521 tgtctacagt aacaccatta ttagcttttg caggaatctc tgtaggtaat caattagata
    23581 tattaaagac tttgagttgg aagttagtag ttatatcatt tatagttatg acatctactt
    23641 actttggttc tgcttttata tctcaaacag ttttaagatt aaatggaatg ctttaaggag
    23701 gtagtaaata tgaatgaatt aaaagcaaaa attaaagagg aaataaagtt attatctgaa
    23761 gagaaaaaga catcatttga aaaagtttct gactatttat tttcaaatcc agaattagca
    23821 tttgaggagt ataagtcaca aaaagcatta tgtgatttgt tagaagaaaa tgaatttaat
    23881 gtaactaaag gtgtaggagg attagaaaca tcttttgaag ctgtgtattc aaatggaact
    23941 aatgggaaaa cagttgcttt tttagctgaa tatgatgcac ttccaggaat gggacatgca
    24001 tgtgggcaca atatcatagg gacaagttct gttggtgcag gtatcatatt aaaagaaatc
    24061 atgaaaaaac ataatataga agggactgta aaggtttttg gaacacctgc agaagaaaga
    24121 gtaggtggaa aaataactat gattaaagaa ggtgtattta ataatgtaga tgctgcatta
    24181 attttacatc caagtgatgc ttcaatgcct gatgatatat catttgctca agttaattta
    24241 aaatttgatt ttactggtaa ggcatcacat gctgctgctt ttccttggga agggaaaagt
    24301 gccttaagtg gagtaatagc actatttaac agtgtaaata gcatgagatt acatcttaaa
    24361 gattatgcaa gagtacatgg aattataact gatggaggta gcatacataa tataattcct
    24421 gaaaaatcta cagctatatt taatgtaaga gccttaagta tagaatattt aaatgagatt
    24481 tgtgaaatgc ttaaaaattg tgctaaagga gctgcaattt ctactggaac taatgtagaa
    24541 atagttcaat tagatgaaat atacaaagag attaagaatg attctgaatt agtgaatata
    24601 gttagacaaa attttgaagt tttgggtgaa gactatgttg aaagagattt aagtcaaggt
    24661 ataggttcaa ctgatacagg aaatttaact catgagatac ctgcaataca agcatatata
    24721 aaattaaaag aaaatactgc aactcataca gatgaatttg ctgttgcagc tggtggtgaa
    24781 gaaggcagag tagcacttat aaaagcaatt aaggtgttag caatgtgtgg agtagatatt
    24841 ttgtatagta aataatatat aattttaaaa tatattaaga aaggaaatcg gattagacat
    24901 gatattaaaa caagtaatag aggtttatga cattttagat aaagcaaatg ctaatgggga
    24961 agaagtaaaa acttacttac aaggttatgg tgaagtagat gtaactgtaa aagaattgtc
    25021 ttcaagtaaa ggttcaacag atttagtaaa gcttacaatt cctggaaaaa atggaaaatt
    25081 aaaaggtgga gatgctccta ctcttggtat tttaggtaga ctaggaggga ttggagcaag
    25141 accagaagtt ataggttttg tctcagatgg tgatggagca ttggtagcaa ttgcagtggc
    25201 tgctaaactt ttggatatgc aacgaaaagg ggatatatta gatggtgatg ttgtaatttc
    25261 aactcatatt tgcccagatg ctccaactaa agaacactat cctactcctt ttatggattc
    25321 tccaattgat atgatgacta tgaatgaaaa tgaagttgat agtagttgtg atgcaatact
    25381 ttctatagat actactaaag gaaatagagt aatcaatact agaggatttg caatatcgcc
    25441 aactgttaaa gaaggctaca tattaaaaac tagtgataac cttttagata ttatgcagac
    25501 tgtaacaggg aaatctccat ttgtattccc tttgtctatt caagatataa caccatatgg
    25561 aaataatctg tatcacttaa atagtatttt acaaccagca gtagctacag atgcaccaat
    25621 agtaggagta gcaattacaa cagagatgcc tgttgctgga tgtgctacag gtgcaactaa
    25681 ttttagtgat ttagattcag ctgggagatt tgcaattgaa gttgccaagc tatttggtag
    25741 aaataagtgt gatttctatg ataaagaaga gtgggaaatg cttattaaga gatatggcaa
    25801 attaaataga tttcaaacat ttggtataca gtaattagaa aaatattaag tttatataat
    25861 ttgtgatata actatttaag aatatataaa caattaggaa taaaagtaag aataaagcac
    25921 ttagttaaaa actttaaaaa taaaatattt atttgtttat ataaaaagga ggattctggt
    25981 tattgggatt ctctttttta tgaatacaaa taatatattg taattataaa aaaaggagcg
    26041 tttcaaagtg atttttttaa tcaccttgag acaactcctt atatttttat ttaaattcta
    26101 ttttttatta agttgctgga gttccaccac catcaggagg agtagtagag ccaccaccat
    26161 tatttccacc accatcagga ggagtagtag agccaccacc attgtttccg ccattatcag
    26221 gaggtgtaga accgccacca ttatcacctg tgttattatt gttattatta ttttcttctg
    26281 gttggttatt gtctggtttt tttgtatctt cagatgatgg ttgagaactt actttagtag
    26341 gagcagtacc ttcaataaat gctgctttag agccagaaga ttgctttcct ccatcctcta
    26401 aattaatttt tgtaaaatat acatttttag gaacttcaaa ttcagtaacc gttaaattag
    26461 catgtatttt ttccataatt ttttcccata gttttgcagt actagtactt ccatgtggta
    26521 cttctctacg ttttatagtg ttaccagaat catcttttct accagcatca tctccaatat
    26581 aagttgcacc aacataataa ggagtgtaac cgacaaacca agcatcatat gcactatttg
    26641 tagtacctgt tttacctgct acaggcattc cctttggaag tgtagcaaca ccaccagtac
    26701 cttcagtaat tacgctttct aacatatctg taacaacata agctacttca gggtctacaa
    26761 ctttatgttc ttcaggagca tttttaacta ataattgacc atcaaaggta gttatagtag
    26821 taaaaataga aggttctaca taaataccgt gatttgccaa tgtaccataa gcagcagcca
    26881 tttgaagtgg agtaatacca ttcgccatac cacctagtgt caatgatggg aattttctat
    26941 cacttgcttc agatgaacct gagtgattat tctttaaagt tgttatacca aagttcttta
    27001 agtaatccat cattatatct acacattcat cataagagtc tccaagcatt tcagcagttt
    27061 tgacagctat cgtgtttgaa gatttagcaa gtgctttacg taaactcata gaaccatgac
    27121 cagcagtagt agttcttgga ttccatttat tattttcttc aaacttatat cctcctcgag
    27181 aatcacttag agcagttgct tgtgttattt ttagagtatc aatagctggc gtatatattg
    27241 ctaaaggttt tatagaagaa cctggctgat gagggttagt agcacgattt aaagtttttc
    27301 taccacttat atttcttcct ccagctagtg ctcttatttc accattttta taatctaaga
    27361 ttaccattgc agcttgcggt tggctaactc catcaggacc gaccatatgt cctgggaaat
    27421 tgctatttct atcaaattct tcttctaaag catcttgcat tttagggtct atagttgtgt
    27481 ttacaattag accaccattg tagaataagt tttgagcttc atcatttgta tgtccttgtt
    27541 ccattaaagc atttataact tcactttcga taaggtcttc tacagatgaa gaaactttat
    27601 ctgatgattg aggcaatttt atttctattt tagctttgat tgcttcatca tattcacttt
    27661 gttttatata tttcaattct aacattttct ttaaaacaat ttcttgtctt tttttagctt
    27721 caggattact tacagccttt ctaacaacta atgtacctgc ttttaattgt ctataagtat
    27781 cattagatat aagctcccaa gattttattt tttcaatcat atcaaagtcc acttgagtag
    27841 ggtcatctaa atcatcatca gttgtgttaa caaaaaataa taatttattc tctaaatcct
    27901 ccttagtttc atttccctct aacttagaag ttttataggc tgaaaatctt gatggatttt
    27961 tagttgaacc agcaagaagt gctgactctg ctagagtaag gtcagctgca gacttatcaa
    28021 aataaccacg tgcaccagcc tcagcacctg ctagacctct accaacgaag aagttattta
    28081 aataagtttc tagtatttta tctttactta ctgttttact catctcatgt gcatagtaaa
    28141 tatcctttat tttacgaggt atagtttgct gttcagttgt taacagcatt ttggatacct
    28201 gcataggaat agtactacca ccttgcttag tacctgtaag ggtctttaat actgacctaa
    28261 ataaaccttt aatatcgaca cccttatgct cataaaaacg ctcatcttct attgcaatta
    28321 cagcatgttg aagataaggg gaaatcttat ctaatggaac gggtgtcttt ttatttacac
    28381 ttggagctgt agataatgtt tttccattag cgtatttaat agtagttgtt tggttcgtct
    28441 gtttatctaa aacagcttct gtaactggag ttacatctct tagtgacgca aatactagac
    28501 cagcagtacc tgctgtacca acaactagta aaactaaaaa tactatccca aatactctta
    28561 gttttttaaa tttatcgctt tttttagatt ttttcttgtt ttttgttgaa cgagtcttgt
    28621 tagctgaagt tctattaatt ggtttatttg tattaccaga tgagctaact ttttttctcc
    28681 tgattttatt tccattttta tcattatcgt tattcataag attttaacct ccttacttaa
    28741 tgcaatatta taacacaaat aggagtagtt ttgtaattaa tagaaaaaat gaatttgcta
    28801 taatattctg tacattgtat atgtataaac gtaatatatt aaaaagtcta tatttttatt
    28861 ttatttattt ttgacaaata ttataaaaat tatgccaaag ctacatataa ataaatagga
    28921 ggggataatt ttgaatagaa tagtagatag aaaaacaaaa aatgaattta gaaaaatcat
    28981 agctattttt ttagtaattc ttttcttgtc tgtatttata ggcagtttta tatatataga
    29041 taaaacttta agaccgacaa taacagtttt agcagagact aaagctcttg aactagcaaa
    29101 taggtcgata aataaagctg ttgctgagat ggtagaagga aaaataaatt atgaagattt
    29161 aatggatata caacttgata ataatggtaa aataactatg atacaagcaa acactataat
    29221 gatgaatgaa attgcatctg caatagcttt agaaatacaa gatgaattaa aaaaggataa
    29281 gacagcaagt tcttacatac ctataggaac agcattagga agtcctatat tagctaaata
    29341 cggtcctaaa cttgaagtat ctattgaacc tataggaaca gtatcagtaa actttaaaac
    29401 ggaatttgag tcttcaggta taaatcaaac tagacataga atatatttag aagctcaaac
    29461 acaagttaaa gtagtaatac cacttataac ttcaacaaaa caaattaaag ctcaaatacc
    29521 tatttgtgaa actataatag taggtgatgt tccagaaagt tatgtaaata ttccagaaaa
    29581 aaatctagga aatgttttac ctaacactgg aaagaatacc aacaagtaat gtaaagttgt
    29641 atatttttaa ataaattcaa aataatagtt tataaataaa atttttggaa ataatattaa
    29701 tataatttta ataaaaattt atattttata ctatgtaaaa tatctaatat atttggtctg
    29761 taggttaaat aaaagtacct ttagaccaaa tatattatta ataacttaat aacatcttaa
    29821 aacttattta tttatattat ttacaacatc catttaataa atacaccata acctacagct
    29881 gggtcgtttt caattgcatg tgacactgct ccgattattt tattatcttg aactattgga
    29941 gtaccactca taccttgtac aataccacca gtttgagcta aaagcttttt atctgtaatt
    30001 ttaattttaa aacttttact ttctggatgt ttttggtttt ctatatctat aatttcaata
    30061 ttatattttt tacacttatt aaagttatct tgtaaaatta tttgagcttt tcctaattta
    30121 acttcatcta aagatgctac tttatatttt tttaacttgg aaatatcaaa gttattaatt
    30181 tgacctctta ttccaaaatc agtattttct gtaaagctac caataatatt ttctcgtttt
    30241 gcatttatac atccaacact acctttataa gatttttcta tattaaggtg cttagttgta
    30301 gaaattgaac ctgttttaat aggtattttt cttgcattac caacacttat tggatgacct
    30361 acagctccaa actctgatgt atctggattg atatacgtta aagtagcaaa tccagaaagt
    30421 aaattgttaa aactaatttt ttctaatatg tgtttggtag ttttcattgt tataagttgt
    30481 ccacctctat ttaataaaat agatacttgt ttttcttctg gtaaagcatt taaggtattg
    30541 gcaaagtcac tatatccatc aacttcagca ttatttacct ttactatagc atcacccaat
    30601 ctaaatggag atgcttctcc aggatttcta actatgatat tttttaattc tgcgtcaatt
    30661 tgaagtacgt ttccaattgg tattaaatat tcaggttcat ttttttgtaa attttgtgca
    30721 taaattaaat tatttgagaa aaaatataat aaaaataaaa atgttaaaac aattgtaaat
    30781 tttgacttag ctaagttggt ttttttactt aaagtattat ttttaaaatg aaaattttta
    30841 agttgcataa aacacctctt tcttattaaa ttattttaat aatagaattg aagttttctt
    30901 gctgcttcta tattatgttg tgcaagaatc atgttttgat gcttggaaaa ctagctcaat
    30961 aacaccttag ttttcataaa aataaataaa ataaatagtg tatatgataa aataaataca
    31021 tattcatata aataaaaata aacaataact gtctagcata agaaaggagc aaaaaatgaa
    31081 aaaatataga ttgttagtta cttgtataat tgccatggga atcataatta taggaacatc
    31141 aaatccagtt agcaattttt acaagactac aaatttgatt agttcaggaa atatcacaaa
    31201 tgaaaaagca gataaagatg aaaattcaaa caaaaataat aaagataaaa atgaagacaa
    31261 atctaattct aaaagtaata aagataagtc atcagaggac aaatcgtcag ataataaaaa
    31321 tgaaattcaa aaaaataaaa aacttttaat ttgtatagac ccagggcatc aaggaaaagg
    31381 agatagcaat ttagaaccag tagctccagg ttcttcctct aaaaaagcga gagtatcttc
    31441 aggaacagag ggtattgcta caaaaaagcc agaatatgtt ttaaacttag aagcatctct
    31501 tgttttaaag agtatattag aatctaaagg ttataatgta ataatgacta gagagacaca
    31561 tgatgtaaat ataagtaatt cagaaagagc aatacttgct aatgacaaaa aagcagatat
    31621 ggttgtaaga atacatgcag atagtttaaa taattcttca aaaactggag catctatatt
    31681 gattcctgaa aaagatggaa aatatacagc tcctatatat gaagaaagta ataaatgtgc
    31741 tgaatttatc aaacagaata tggaacaatc aggtatacaa atcaatggaa tcgttcaaag
    31801 aggtgatttg actggattca actggtcaaa agtaccagct gtattagtag aaatgggatt
    31861 tatgagtaac tataatgaag accaaatgat gtcaaatcca gactaccaaa gaaaaatgat
    31921 gcagtgtata gctgatggat tggatgcgta ttttaaataa gatatgaata gagaaaaagt
    31981 taggttggta ttatttgcct aatttttatc tctatttttt attgtacata acacaaagaa
    32041 gaagtttatt ttaggttaaa ttgtcgtaaa tataactaaa aatattggga atacttgatt
    32101 taagtttaaa aagaatatat tatagtatag aatgtgtaaa atttttttga gaggtgttga
    32161 aatgctagta gtagaaaatg tgagtcatgg atttggtgcg agaacaatat tagaaaatgt
    32221 atcctttaga cttagaaaag gtgaacatat tgcactagtt ggtgctaatg gagaaggaaa
    32281 atcgagtttt ttaaatataa taacaaagaa gcttatgcca gatgctggaa atataaaatg
    32341 gtcttcaaga gctacagtag gttacttaga ccaacatacg gtattaagca agggaaaaac
    32401 tataagagaa gtgcttagag aggcttttaa gcatatgttt gacttagagc aagaaatgat
    32461 tgctatgtat gacaaaatgg gagaagctag tgatgatgaa atgagtaagc ttcttgaaga
    32521 aacagcagag atacaaacta tacttgaaaa tagtggtttt tatatgatag atgcaaagat
    32581 acaagaagtt gcaaatggtc ttggtcttgg agaaattggt cttgataaag atgtaactga
    32641 cttaagtgga gggcaaagaa caaaagtact tcttactaaa cttctacttg aaaatccaac
    32701 tattcttata ttggatgagc ctacaaacta tttagacgaa gagcatataa catggcttac
    32761 taagtacctt caagagtatg agaatagttt tgtcttagtt tctcatgata ttgaatttat
    32821 aaataataca tgtaatgtaa tatatcatat ggaaaatgga gagttaaata gatataaagg
    32881 aaattatgat gaatttgtaa gacttaatga tataaagaaa cgtcaagaag aacaagctta
    32941 tgataaacaa gttgaagaaa gaaaaagact agaggatttt gtagctagaa ataaagctag
    33001 agtagcaact agaggaatgg ctaacagtag gcaaaagcaa cttgataaga tggaaatatt
    33061 agaaagacca aaagaaaaaa taaaacctac ttttgctttt aaagatgcta gagcagctag
    33121 taaaataatt tttgaaacag aaaatttagt tttagggtat gatgaagcat tgacaaaacc
    33181 acttaatttc catttagaaa gaggaaaaaa gattgcctta aaaggaatga atggtattgg
    33241 aaaatctacc ctattaaaaa ctttacttgg aataataaaa ccatttgaag gaaatgttaa
    33301 attaggtgac tatttggaag ttggatattt tgaacaagag agttcaagag aaaatagtaa
    33361 tacacctatg gatgaagttt ggagtgaatt tccagggctt acaaactttg aagttagaca
    33421 ggctcttgca aaatgtggac ttacaaatga acatataacg agtcaaatga gagtattaag
    33481 tggtggagaa gctgctaagg ttagactttg caaagtaatg ttaaaaaata taaatttctt
    33541 agtattagat gagcctacaa atcatttaga tgttgaggca aaagatgaat tgaagaaggc
    33601 tatcaaagag tttaagggaa cagttctttt agtatgtcat gagccagaat tttattcaga
    33661 aattgttgat gatgtatgga atatagaaga ttttacaact aaaatcgtgt agtgatttaa
    33721 cttattgctg gggggatttc atgaaaaagt ttctaaatgt acttttttca atttgtatta
    33781 gtattgttat aatagtaggt gttattaatt ttactgttgg atttaaacaa ctttattatt
    33841 ttgacattga ttacttaaat atatcagagt tatctggttt atctaaagat gatataaaat
    33901 tgaactacga ttatctaatt gattataact taaataagaa tgtgtctgag ttcaaattac
    33961 caacattaaa atcttctcca caagggaaga tacattttga agaagtcagg aatatatttc
    34021 aaaatataaa taaattagct aaattattat tggtagtttc tttagtagga attatattga
    34081 gtgtaaaaaa taaaaatata aaaatcttaa aaactacatc aataacactt ataattatgc
    34141 cattattatt aacagttcca attttattaa attttgaaaa gtcatttatt atttttcata
    34201 aattattatt tagaaatgat tattggatat ttaatcccga tttagaccca gttataaata
    34261 tattgccaga ggaatttttt tttcactctg gaatgatgat tttaatatta attttgttag
    34321 taagtatagt actgtttgta atgtataaat tatgtaaatc tttatcaata aaaatatttc
    34381 aatgttaaat agagggatat ttttatttcc aaaataagat aataaaaaag gattagatta
    34441 aaagttatac aataaaaata gctgtgcaat aatatttaga ctatgaaagt agttgaaaaa
    34501 tatttatgca cagctattta taatagaatt tactttttac tagtgatttt aactaaatct
    34561 tgaaatttac tcataatgta attgtaatta tcttttttat gaggtaatat acaactactg
    34621 caatctttga tacctttatc tgtataccta aagtttccac cacagttttc tcctaaagca
    34681 tacaaaggac aatagcaaaa tagacagtta aactcttctg gtttattagt tttatgacaa
    34741 gggaaaaatt cgcaatcttt gtgattaaaa aacttataat tttcgcccat attttcctcc
    34801 taattaaata aaatttaaat tttttatact atataagatt ttggtgataa tataattata
    34861 ctaaataatt ttatgaatag tcgataatat agtattatta atcatagtat taatggtata
    34921 attagtcaac agaaaaataa tgtaaaaata atgtaagtgt attttgtaat tagaatatgt
    34981 tttataacaa aaaatgaggt gattaagtga aagaaattca agaaaaagca cttcttgtag
    35041 gtctgaattt gactacaata gtgaaaaaaa atgatgatat agacactaat gaatctatgg
    35101 aagaattaaa agaactaaca aaagctgctg gggcagaagt tgtaggtagc ttaattcaaa
    35161 ataaacactc tgtagatgca gcttattata taggaaaagg taaagtagaa gaaataagag
    35221 cctatagtga ctctttagat gctactttag taatttttaa tgatgaatta tctggtgctc
    35281 aaatcagaaa tatagagaat gttgttggaa gaaaagtaat agatagaact actttaattt
    35341 tagatatatt tgctcaaagg gcacttagca aagaaggtaa attacaagtt gaattagcac
    35401 aattaaaata tagattgcca cgactttatg gaatgggtgg tgagatgagt agaacaggtg
    35461 cagggattgg tactagaggt cctggagaac aaaaactaga aatagataag agacatatac
    35521 ttaataaagc agcagatata agacgtgaac ttaaagaagt aaaaaagaat agagagacac
    35581 agagagttaa gcgtttaaag tcaaatatac cgattgtagc acttgttggg tatacaaatg
    35641 caggaaaatc taccctgttg aacgaattaa taaagacaca caaggattat gaacaagaaa
    35701 aagaagtttt tgtaaaagat atgctttttg caactttaga tgtaactttg agaaaggctc
    35761 ttttgccgaa taaaaaagaa tttttagtag tagatactgt tggatttgta agtaaacttc
    35821 cccatgattt agtagaagcg tttaaggcaa cattggaaga agtacagtat gcaaatttaa
    35881 tcttacatgt aattgatgca acaaatacta gttatgaatt gcaaaaaagt acgactgaag
    35941 gtgtattaaa agaacttggt gtaaatgata aaaaacatat acttgtatat aataaagtgg
    36001 acaagctaga attggatata taccctaaaa gtcaagaaga tattgtgtat atttctgcaa
    36061 aacaaggcat aaatatggat aagttattaa atatgataga aattgcttta atggaaaata
    36121 cttattcagt aagtttgatg ttaccttatg agagaggtga tatatttagt agaataaaag
    36181 ataaatataa tgtggagaat tttgagtatg gggaaagtgg tataacgcta gatgcagatt
    36241 tagatgaaga agattttaat atctatagag agtacatact agaaaaatag gttgaatatg
    36301 gatataaact gggaaaatat agataatctt gaagattatt ttataaccta tcttctttat
    36361 aaagaatcta aaacagtatc tcaaattagt aaaattagaa atatttcaag tactgaagca
    36421 agtgagcaac ttatacaagc aaagttaaaa ataaaggaaa tgcaaaaaga tgattttgag
    36481 gcatctaagg atattttgga taaatttcta gaactagata aaattaagag acttgatttt
    36541 atggatagct tagatgacga aaaaatggta tactttaaga gaaaggtttt caaaagaatc
    36601 cttgtagaaa aaaatgctga agatttaatt gttttaattt gggcgacagg tgagctaaaa
    36661 gatgataggt ttttgaaatt gcttcatcag ctcacaaacc acagacactc agatattaga
    36721 agaataactt attcagcaat cagaaagatt gaatcaccaa gtagtagaga agtactgcaa
    36781 aaaggtctct acgacaaaaa tgcacagact aggcagtact gtgcaaaagc tctttcaaaa
    36841 ttgggagatg aaaacagttt aaagatttta cagcagttga aagacaagaa taagaatttt
    36901 gaaaaagaat atgtgcttag agcttatgac gaagccatta agtcattgga aaatgcaaaa
    36961 aatttgaaaa agtaattttt tattaaagca atttgtttac ttaatgatgt atttctaaag
    37021 tttaacaagg taataaataa attaatggga ggggtttcaa atgatagtaa gacgttgtgc
    37081 aggtggagta gtgttttatg ctaataaagt acttattgta aaaaatgata ggggtgaatg
    37141 gacacttcca aaaggaaaga tactaggagg gggacttcca tatgagagtg ctgttcaaag
    37201 agttaaagta gaaactggca tagatgctaa aatgatagat gtggctggcg atactatgta
    37261 tgaatttttc tcaagaagta gacaacaaga agtttgtaat gcaataatgt ggtatgttat
    37321 ggaagcttgt aacactgatt gtgtacttgc tcctgaattt caagaaggtg gattttataa
    37381 agtaaaggat gctttagaaa tgttatcaca tcataaagag caagctttag tagaagtatc
    37441 ttataaaaag tttaaggaat taaagaaatt agtttcagag ggcgatgatg ttccagcaaa
    37501 ttaattgtga atttagagga ttctgaggaa gggatagccc cttccttttt taattgaagc
    37561 agttttaagc gtaaattata tagtctcttt aaactatgat ttatcaattt agagatttag
    37621 tagtttatat ttaaaatcag taagatatat ttaaaataaa aattaaaaag tatacaattt
    37681 tattatataa ttgtcttatg atgttgatta aagaagtatt aaaagtccat ttatttttaa
    37741 atagaatgat tttataaata tatatttgat gtgtatatta gaaaatgatt aaaataggag
    37801 gaaatacaat gagcaattac aggacattac atgaatttgg aacggatgaa ataacgattg
    37861 aaaagtctgt ttttattgga tatgctaagc ctataaagag tgaagaagaa gcattagagt
    37921 ttataaatga aataaagaaa aagcataaag atgcaactca taatgtgtgg gcttatactg
    37981 taggtaaaaa tatgaatata caaagatata gtgatgatgg agaaccacaa ggaacagctg
    38041 ggatacctac attagaggtt ataaaaaaag aagatttgag agatgtagcg gttgttgtta
    38101 ctaggtattt tggaggaaca aaattaggtg caggtggtct agttagagct tatacaaaag
    38161 gtgctaaact gggacttgaa gcaggtaaga taatttataa ggtaatgtat caagaagtta
    38221 aggttaagat agattatact caacttggaa aagtgcaaaa tgagttaatg aatttggggt
    38281 attttataaa agatactgta tatgaggata atgttgaaat agtagtatat tcaagattag
    38341 aagatgtaga gaaattatca gaaaaaatga ttgatataac aagtggaaca ggaaaaatag
    38401 ttttaggaga ggaattttat ttgtctgaac aaaatggaga aattttaata taatctaaaa
    38461 ggttattaga atagttaata cctcaaatag ccaattagta tttttaagtg aaaagccatt
    38521 aaattgattt aatctaaatc aatttaatgg ctttttatcg gattttgcac agaatccttt
    38581 ttttacttca aataaaccga ctaaaagtaa aaatatccca aatatttttt ttaatatatc
    38641 tgaagacaga taattagcta atagtgaacc aaatacagct cctaaaaccc caaacacagc
    38701 tataggtata accaatttaa aaattacatt tttatttttt atatgtatag caagtgctat
    38761 aagtgtcata gggatagatg aaagtaaatt tacgctttgt gctattttag tgtctatgcc
    38821 agcaagtaaa acgagtgcag gtataaggat tgttcctcca cccattccca ttcctccaat
    38881 aattcctgca aaaaatccaa ttagagcaaa taacattaaa acaccatcct taatgctgca
    38941 attatcataa ttattccaaa agaaattcta agaaactttc cagtaacctt atttagtaat
    39001 ttagctccta taataccacc aagaatactt ccaactgcaa ctttaattgt taagttaaca
    39061 tcataagtac ctttagatac atataaaaca gaacttgctg tcgttaagaa tattattata
    39121 gaaagagcag ttgcatgaga tttatgttct tctaccttaa cgatgtcatt taatattgga
    39181 actaaaagag tacctcctcc agaaccaaaa actccattta taaatcctgt aaaaactcca
    39241 attatcgtat tttttaaatt aaaatcaaag tattttttct ttaaatcatc agtttttttc
    39301 ataaaaatca ccttctgaaa tagttttacc aaaataggca aattatattt atataaaata
    39361 agattaaata taatctttca tgtttgttta attttgcata aaaaaaaaca tattaaaaca
    39421 acatattaat atatggtata atatattaaa acaaagtagc aaatttgaga ggagataaca
    39481 atgtcaaata taaaaataca aatagacaaa actgtagaat ggcttataaa taaggttaat
    39541 gaggcaaatg caaaaggatt aattgttggt gtatctggag gaattgattc ggcagtagtt
    39601 gctaatttaa ttaaaaaggc atttccagaa aactctatgg gagttataat gagcataaaa
    39661 agtaatcctc aagatagaga agatgcactt aaggttatag agggatgtga tatagaatac
    39721 cttgatttag accttataga accacaaagt gctatattag acatggtagt aggaaattta
    39781 aaagataaac atttatatag agaagaatat ttaaagatga cagatgcaaa cttaagagca
    39841 agagtaagaa tgagtacaat ttatacaatt gctaacaatc taggatatct ggttgttggt
    39901 acagacaatg ctgcagaaat acacacagga tattttacta aatttggtga tggtggagtt
    39961 gatattttac ctattgcaaa tttaactaaa ggagaggtgt atgaatgggc aaaagagctt
    40021 ggtgttcatg aagatttaat aaacaaagct ccttcagcag gtctttggga aggtcaaaca
    40081 gatgaagatg aaatgggaac tacttacaat atgatagatg ctgtattaga aggtagattg
    40141 gatgaagttc ctaaaagaga ccaagagata attgaaagac ttcatagatt aagtgaacac
    40201 aagagaaaaa cgcctgcaca acctcctaag ttctaattta ctatttataa gatttgtgat
    40261 aaaatttaca agtgatgaaa attagaataa ttaattgtac gtattaagga gtggaaatat
    40321 gggacgtata ggtaatataa ttaatagaaa aggtaaacaa gatgctcaaa gagcaaagat
    40381 atttactaaa catgctagag caatagcagt tgcagctaag gaaggtggag cagacccaga
    40441 gtacaatgca gcgttaaaaa cagctataga aaaagctaag gcagataata tgccaaatga
    40501 taatatagat agagctatcg ctaaaggtgc tggagcaggt gctggagaag actatgaaac
    40561 tatagtttat gaaggatatg gacctggtgg agttgctgtt atagtagaaa ctttaactga
    40621 caacaaaaac agaactgctg gtaacgtaag atactatttt gacaaaaacg gaggaaactt
    40681 aggaactagt ggatgtgtgt ctttcatgtt tgataaaaaa ggacaaatat tagttggttt
    40741 aggagatgga gtttcagaag aagaattgat ggatgttgca ttagaagcag gagctgaaga
    40801 tttcataaca gaagaagatg gttatgaaat aataactaca ccagaagatt tttctagtgt
    40861 tcgtgatgag ttaaaagcta aaggatatga gtttatatct gctgatgtga agatgatacc
    40921 tcaaactaca actgtattga ctgaagaatc tcatttaaaa atgatgaata aattagttga
    40981 tatgcttgaa gaagatgatg atgttcaaga tatatatcat aactgggaag tagaataaat
    41041 agtataagca tattgaaatt tataagtatt gaatcaattt taacatgtga taaattttat
    41101 agaataagaa acactaaaat agacatacgc acctctaacc tatatttgca taataatatg
    41161 taagcatagg taaggggtgt ttttatattt ataggttaag aaatttaaag taaattttga
    41221 gctggactcg attgtctata aataattgat gggtatataa cttgttgctg aataccattt
    41281 atacgcccag ttactgtatc aataatcatc ctaagactac gttctgctgt ctcttccatt
    41341 tttaaatcta taactgtcaa aggaggaata cttcttgcca ttagtcgtga aggtccatta
    41401 cttgctgcaa atatttgaat atcctctcca attacaattc ccgattcatg aaatgcattc
    41461 atcataccaa gagctaccac atcatgatta caaaaaatta ctttttttag tgaatttttt
    41521 gcaagcattt tttgagcaat atcatatcca ctatctattt tattagaaca ataatatata
    41581 gaatctgata gatgtattcc atgttcttta catgttttta aaaaagattt accccttaaa
    41641 gtcatacatg taaaggaagt tgggttgaat acaacagcaa tatcattttt accattttga
    41701 atagcatgta aagctgctat acgaccagtt tcctcattat caatagatac acttgaaaaa
    41761 ccaggtattt cacgatttac aacaactaca ggaattttag gtttattttt tactagatat
    41821 tctatatcat cagcattgat acctgttaaa acaattccat cataataatt atttgcaaaa
    41881 aagtattcat catcacatag atgaccaact ttgtaaggtc gtatgatgat atttatgttt
    41941 aaatgttcta aagaaattat gtggtttatt gcttgaagta tattggttga tgccaactca
    42001 aatccctcat cctgccaata aaaagctatt ttaatattat tatgtttaat aggagtagag
    42061 cgtttatatc caagcttatc agctgaattt aatataagct cttgtgtatg tagcggaatc
    42121 ctgcgttcat ttcctttacc acttaagacg tacgagacag ttgctgaaga aagaccacag
    42181 tcttttgcaa tatctttgat tgttgccatg ataaaatcct ccttaaatag ttgcttaaat
    42241 ttgcttatac caataatctt aacatatatt caactaaaga acaatattct acaaggtgca
    42301 tattttacag gattagaata aataaattaa aaaaaacttc ttacttatgt tgacataatt
    42361 tagtttatag gattataata tgcttaaata agcttatgat taacttgaat taagcaaagt
    42421 taagcaggaa catgcaatgc tagcttgcaa tgtgactgca aagggggaaa aggtatgagt
    42481 aaggtaaata tatttgaagt tggtcctaga gatggatttc aaaacctgaa agagttttta
    42541 gaaactgata aaaagcttaa gattattgat ggtcttattg cttctgggat taaacaactt
    42601 gaaattagtt catttgtaag cccaaaagca atacctcaga tgaaagatgc aaaagaagta
    42661 gcaacttatt gtgtagaaaa atatcctgat gtgaaacttt atgcattagt tccaaattta
    42721 tatggtgcta aagttgcatg ggagtgtggt ataagagata tatcctatgt tatatctttg
    42781 agtgaaactc ataataaaaa aaatataaat cgtacccatg aagagtctat tgatgagctt
    42841 aaaaaaataa tgaatactta tccagacatg aatatatgta ttggaatggc tactgtattt
    42901 ggatgtcctt ttgaaggttt accaaaaatt gaagatgcca taagatttgc taaacgcctt
    42961 tgggaaaacg gtatcaggga gataaatcta gcagatacaa tagggattgc tgaccctaag
    43021 caagtaagag aaactattag tgcattagtt gaagctttac cagaatgcag atggcaagta
    43081 catattcatg atactagaaa tatgggaatg gttaatactc ttgtggctat tgaatctgga
    43141 attactactg ttcagtctac acttggagga ttaggaggat gcccatttgc tcctggagca
    43201 tctggcaata ctgcaactga agatttagta tatatgcttg aacgtatggg gtatgataca
    43261 ggagttgatt ttgttaaact tcttgaatta tcaaaatatc agaagagttt tgtaaatgga
    43321 gtatatagtg gtcatcatgt aaatataaag tctgatagtt gtaattgtta gttctattga
    43381 ttaatcgatt aaaaaaatat gctgattggt aaaatagatt tattgataaa aaatataaat
    43441 tataaaatac attatctaat aaaacaaata aaaaaattga gggggattag tatggatatt
    43501 atagctttac ttttattttt aggagttatt attattgcat ttgtacgtaa gaataatgca
    43561 ggtattttgg ctctagctat tggtgtcata gctgttagaa tttttggaat ggatgataaa
    43621 gaactttatg gagctataag caactcaatg tttactacac ttgttggtat aacactactc
    43681 tttgcaatag tgaactcaac aggagcatta aagcttgttg cagaaaaaat tgtagctgct
    43741 tctggtaaac gtgtttggct tatacctata gcagttttta tagcaggatt tgttgttgct
    43801 ggtgttggac ctggggcaat tccagcactt gcaattatcc cagcaatggc tgttcctgta
    43861 gccataacag ttggttataa tcctgtaatg cttgcactta taggtgaatg tggattaatg
    43921 gcaggtcgta tgactcctat tactccagaa ggtcaaatta taacaaccgt tgcagaaggg
    43981 gttggaattg aaaatgttat gcctactatc ttagcctgtc aaactctttc tacaattgta
    44041 ttttcaatag tattgtttat aattttcaaa ggatataaac ttaaaaaacc tataaatgtt
    44101 atagatagta agcaaataga aaaattcaat ataaagcaga taatttctct aataagcata
    44161 gtagttatga ttgcttttat cataattttt gatatgaatg ttgggcttgc agcttttgca
    44221 gtttcagctg tacttatttt tttcaatatt gctgatgaag gagaatgtat caaatcaatt
    44281 ccatggagca cgatagtaat ggttcttgga gtaggtgcaa tgatgacaat cgtagatgca
    44341 gcaggaggta ttgacttgat gagtaatgca ttatcatcac tgatgaatag taaaacagct
    44401 actccaatta tgagtatttc agcaggactt atgtctatgg ttagttctgc tttagcagta
    44461 gtttatccaa ctatgatgcc tatgtgtgtt gacatagcta aggcagttgg aggagtagac
    44521 ccactagcac ttattgctgc agttggtgtt ggaggttctc ttgctggtgt aagcccactt
    44581 tctactggtg gggcattgat tttagcagct atgggttcaa gtaagaaaga ctttaataag
    44641 gaagaacaaa ataaggtttt tgtacagctt ttcattatga gtgcagttgg cttattggtt
    44701 attgcagtag tatcaatatt atcatttaat gcaataacac atttaatgaa ctaattagaa
    44761 taactgaaaa taaatcatta aatttaactt ttaatattaa tcaatataat ataatttgga
    44821 ggggaagtta tgaaaaaagg agcattaagc aatataaagg tacttgacct tacaagagtt
    44881 cttgcaggtc catattgtac aatgatgttg gcggattttg gagctgatgt tataaaaata
    44941 gagatgccaa gaaaaggtga tgatacaaga ggttttggac cttttgtaaa tggagagagt
    45001 ttatactatg caaatataaa tagaaataaa aaaggtatca ctctaaacct taaatcagaa
    45061 gaaggaaaaa atatattttt agaaatggta aaacatgctg atgttgtagt agaaaattac
    45121 agaccaggtg taatggaaaa gttaggtctg ggttatgatg agttggctaa agttaacaat
    45181 caaataattt atggagctgt atcaggattt ggatgttatg gaccatattc agaacgtcca
    45241 ggttatgata ttattgcaca ggcaatgggt ggtcttatga gtataacagg gcaagaagga
    45301 ggagaaccaa cgagagttgg taatgctatg ggtgatgtac taggtggaat gaatttaact
    45361 attggtatac tcacagcact caacgctaga aaaataatag gaaaaggaca aagagtagat
    45421 gtttccctcg ttgattctgt tgtatcgtct ctcgaaactg gtatacagag atactttgat
    45481 tcaggacaac ctgaacttat gggtaataga tatgcttcag cctatcctta tgactctttt
    45541 aaggcaagtg atggaagttt tgtaataggc tgtggtaatg acaaactttt tgaaaagtta
    45601 tgtaaaaaag ttctttttag agaagacctt ttaatagatg agagatttaa aacaaatctt
    45661 aatcgttgtg aacattacaa ggctcttaaa ccagaaatag aaaaatggtc tgttaagcat
    45721 acaataaaag aagcagttga cttaatatca gaggctggag ttcctgctgc tcctatctat
    45781 aatcttgatt gtgttacaac agatgaacat atagcaaaag caagagaaat gattgtagat
    45841 attagtcatc ctattatagg aaatatgaaa gtcaatggaa atccagttaa gttgatgaca
    45901 acaaaagcta aaattgatat gccagcacca tctctagggg aaagtaacga ggagatttat
    45961 aatggttggc ttggttttga tagtgataaa ataaaagatt taaaagaaaa tggagttatt
    46021 tgattaaaaa atagctaaac acacttgtga ctttagtcat gggaggttca gttagaataa
    46081 tatcaaaaaa tattaaatca atactgtaaa taaaatatag aattgtcaga agcatttaag
    46141 atgggaaaag ctacttagac attgagtctt tgtggctttt cctattttca ttaagaattt
    46201 tatattatca gaatagatat gtactaaact aaagtattaa caatttaaat taatagaaaa
    46261 taaactacct aattatgttg aataaagact actttagtga aaataaactt atagagatgc
    46321 tatttaaatt attttaatgg aaatatcaaa aatgagactg cattctcaaa aatgagactg
    46381 cgttttttaa gtattttctc gaaaatgaga caaaaatatt gttttatggg ttttattgaa
    46441 gaaaaattct tctgtgaatt acaatttaat caattttaaa gttgaaaatt attaaaaatt
    46501 tagtgaaatt tatgtatatt tcgtttattt tattaaaaat aacaattttt tactaaaaat
    46561 aaagaacttc aatggtgatt ggcatagtac ttgctatttt atattaacaa gaaatgtaga
    46621 aaaaataaca atgtataatg gggggaatat gatggaatct gtaatggaaa atttgaacaa
    46681 tcttaaggtg gaggttaagg acaaagtctg tgttattact ataaatagac ctaaagcttt
    46741 aaatgctctt aatagtgaca ctcttaggga actatcacaa gttattgatg tagtatcaga
    46801 aaatgaggca atattaggag ttattattac tggagaaggt aaagtttttg tagccggtgc
    46861 tgatatacgc cagatgcaaa actataaaag tgaggaaggc agaaaatatg caggttatgc
    46921 tcagggaatt tttgataaaa ttgaagctct tgagaaaaca gtaatagcag cagttaatgg
    46981 atatgcatta ggtggtggat gtgaacttgc tatgagttgt gatattagaa ttgcatcaga
    47041 aaaggctata tttggacaac ctgaagttaa tttaggagtt attccatgtt ttggtggaac
    47101 tcaaagatta tcaagacttg ttggaactgg aatagctaaa gagttaattt ttacggggag
    47161 acaagtaaat gcagaagaag ctaaatctat tggacttatt aataaagtgg ttccaagtga
    47221 tttactttta gaagagtcta tgaagatgat gaaccaaata gttgaaaaag cgccaatagc
    47281 aataagatat gcaaaagttg ttattaacaa agggatagat atggatttaa agaatgctct
    47341 tgaactagag aaagatgttg caggtttaac ttttgctaca agagataagc aagaaggaat
    47401 gaatgcattt atagaaaaga gaaagccagt ttttgaaaat aaatagctat tataactaaa
    47461 attggaacaa tgtagaatat attcaaaatc taaatttcgt gaaaaaatac atatagttta
    47521 attttaaaag gagttaattt atgaatacgg gagtaattat aagtttagta gggattatca
    47581 tagctctatc tcttctagtt gtaatggtta tgaagggaat aaatattttt attatagcaa
    47641 ttgtatgttc atcattagtt gctataacag gaagcctaaa tgtgtatgat gcacttaaag
    47701 tggattatat gacagggttt gttggatttc ttcaggcaaa tttctttatt ttcctaacag
    47761 ggacattaat gggaaaaata atggagatta ctggtggagc aaaatctatt gctaagatga
    47821 ttgtaagatg gattgggaag gataaagcac tactttctat tccaatagct tgtggaatat
    47881 tagcctatgg tggagtaagt gttttcgttg taagttttgc agtgtttccg atagctttag
    47941 aaatttttaa agaagctgat ttgccacgaa gatttatacc agcagctttg acttttggat
    48001 gctcaacttt tgctatggtt gcaccagggg caccacaaat tcagaatatt gttccagcat
    48061 caacattagg gacagatatt atggctggag cagtaaatgg ttttatatca tgtgcagtaa
    48121 tgtttatagt tggaagtaca attttgtaca aaatggtttc aaaagaaaaa gccaatggtg
    48181 gtcattttat agcacatgaa tcagatatat ttgatgaagc agaagcaact aattctaaga
    48241 gagaaaatgg tcccaatggt gtaattgcct taattccatt gatagtgtcg attttaataa
    48301 ttaatgtaaa agttaatgga aaagcgatag taccaattga ggtgggagta tttattggag
    48361 ctttattagt atatttattg ttaaataaat atcaagataa tactaaaata gttggacatg
    48421 ttggtgatgc atgtaaaact acagtagtag caatatgtaa tacttgtgct gtagttgcat
    48481 ttggttcagt agtaaaatca gcagttggtt ttgacttcat agttaatgct atgactaata
    48541 ttcctggtcc tcctattgca ggggctgcag ttggaactac agttattgca ggtatttgtg
    48601 ggtcagcttc aggtggacta ggaattgcag ctccacttct tggaccagta tttttagcca
    48661 agggtgtttc cgctgcagca ttaactagga ctatggcaat ttcatcagca gcattagatt
    48721 cacttccaca caatggatat attgttactg taacaaatgg tctttgtaaa gaaacacata
    48781 aggatgccta tatgccaata ttctgggtaa ctgttttaac cccatttatt ggaaccatag
    48841 tagcagtcct actgtttaca atgttcccgg gattgccata ggagaaaaga taaaaggtat
    48901 aaattatatt ttgatattat aaaatcaatt ttcaaaatat atacaataaa tttcatgttt
    48961 taatactgta aatatgtatt taaaataaca aattgaccat ataaggagga attgaaagtg
    49021 ttaaataaac cattagaggg agttaaggtt attgacctaa cgtattttgt agcaggtcca
    49081 gggacttcta aaatattagc tgactggggt gctgacgtta ttaaggtaga gccaagcttt
    49141 ggagacccag gaagaaagac aggggcaaca atgacaatgc caatagatga ttataataat
    49201 cctttttaca gcacatataa ttcaaataaa agaggtttgt ctataaatct taagagtgaa
    49261 actggaattg aaattatgga taagctttta agcgaagcaa acgtatttgt ttcaagttat
    49321 agaacaggag cattaaaaag actaggtctt gattatgaat cattaagtaa aaagcatcca
    49381 caccttatct ggggtcagat aaatggtttt ggcgattttg gacctgctaa ggataatgca
    49441 ggatttgata cagttgcctt ttgggcaaga agtggggcta tgcttgatat agcagaaaaa
    49501 gatacaagtc caataaatcc acctatagcc tttggagatg caacaacttc ttgtagttta
    49561 tctggaggaa tatgtgcagc tttgtaccag caagctaaga ctggaaaagg acaaaaagta
    49621 atggcatctt tatttgggca agcaatatgg aatgcatcat ctttattagc atctacacag
    49681 tttagtgatg agtatccaaa aactagaaaa aatgctattt caccagtaat aaattcttat
    49741 cgttgtaagg atggaaagtg gatattctta agtattttag agcatgaaag atattttgag
    49801 gcactttgta gattatttgg aagagaagac ttaataaaag aagagaaatt tgcatcttca
    49861 gtagaaagta agaaaaatgc tacagaactt attaatattt tagatggtga atttgcaaag
    49921 tttactcaaa atgagatggt tgaaaaactt actgctgctg atatagctca tgaaaaaatt
    49981 caacatgtta atgatgtagt gactgatgaa caggctattg ctaataacta tatatatgaa
    50041 catacaagta aagatggaaa taagacaatg cttgcatcta ctccagttaa atttggaaat
    50101 attgaagtta acatgacttg tgatgctcca cttataggag aacattcaga tgagatattg
    50161 agagaacttg gatacagtga ttctgatata gagactctaa ttgaatctgg aattgtaaca
    50221 atgaataaag aagcatgtga aatatgttaa taaacatgtg aagtatgtta ataaatagga
    50281 gggaatttta tggattttag attaacagaa gcacaattaa tgcttcaaag agtagcaaaa
    50341 gaatttgcag agaatgaaat agcaccaata gctgctgaaa cagataaaac aggtattttt
    50401 ccaagggagc tttttagcaa aatggctaaa ataggattta atggaattgg aacacctgta
    50461 gagtatagtg gttctggtgg ggcagatata gaaaaggtaa ttgttgttac tgagattgcc
    50521 aaaaaatgtg cagcatctgc agcaatatta tcaatacaca caatatatgc tcaagctatt
    50581 ttgaaatttg gtactgagga acaaaagaaa aaataccttc caatgatggc tgaaggtggg
    50641 tgtgtaggtg cttttgcctt aaccgaacct aatgctggtt cagatgctgc gagagctgca
    50701 acaactgcaa ttattgatga agaaactgat gaatatgttt taaatggaac taagtgtttt
    50761 atttctggtg gaggtcaagc agaatcatta ataatatttg cattgacaga cccatcaaag
    50821 ggaataaagg gaatgtctgc tatcattgtc gacaaaggta ctccaggttt ttcaatagga
    50881 aaaattgaag aaaaaatggg tattcatggt tcagaaactg cagagttaat atttgataac
    50941 tgtagagttc caaagtctaa cttattagga aaagaaggta aaggatttaa tatagctatg
    51001 acttgtttag atggagcaag aattggagtt ggagctcaag ctgtaggaat tgctgaaggg
    51061 gctttagaag aaagtatcaa atattctaaa gaaagagtcc agtttggcaa gccaatttca
    51121 gctttgcaag gtattcaatg gtatatagca gatatggcga caatggtgga atcagcaaaa
    51181 ttattagtat attatgctgc agatttgaaa gctagaggag aaaaacacac taaagaagct
    51241 gctatggcaa aatacaatgc gtcacgtact gcaagagagg ttacaaattt agcccttcaa
    51301 atccatggtg gatatggata tatgaaggat tatccattag agagaatgta cagagatgcc
    51361 aaaataacag aaatttacga aggtacttca gaaatacaca aagttgttat ttcaagagca
    51421 gtactaggat aggaggaaaa gaatgaatat agttgtttgc ttaaagcaag ttccagatac
    51481 taatgaagtt aaaataaata aagagacagg tactctaata agagatggtg taccaagtat
    51541 aatcaatcca gatgatagaa atgctttaga agaagctcta aaaatgaaag atgaactagg
    51601 agcagtgatt aaggttataa gcatgggacc tcctcaagct aaaagtgctt taaaagaagc
    51661 tttggcaatg ggagctgatg aagcttattt aatctcagat agagcttttg gtggttcaga
    51721 tacttgggct acatctacaa ttattgctgc tgctatagag aaggttggaa agtatgatgt
    51781 aatattctgc ggaagacaag ctatagatgg agatacagct caggttggac cagaggttgc
    51841 agaattttta gggataccac aagttactta tgcgaaagaa gtaaaggttc aagatgacaa
    51901 attactagta actcgttata cagagacagg ggattattta atagaagcaa agatgccagt
    51961 tttattaact gctataaaag agttaaacaa tccaagatat ccaagtgtca agggaatctt
    52021 agaagcttat aataatggag atgcaaagat tactgtatta acacttgcag atttagatgt
    52081 tgatacaact caaattggat taaagggttc acctacaaac gtttataagt cttttgtacc
    52141 agttaaagac aagcataatg aaataataga aggtataaat aaaaaagaaa aagctgagaa
    52201 actaatagaa atactattcg atttgaaact agtataggag tgttaagatg atgagagcaa
    52261 aagttaatca aggtataaat ttaaatgatt ataatggtgt ttgggtaata ggagagcaaa
    52321 gggaaggtaa aattaatcct gttacgatag aacttattgg tgaaggaaga aagcttgctg
    52381 accaattagg aaaagagctt gcagttgtga tagctggata tgaagtagag aaagaagtga
    52441 aggaattact tcactatagt gttgataaag tatattacat caatgaccct cttcttaaag
    52501 atttcactac tgatggatat gcaatttcaa ttgcaaattt aatcgaaaga aaaaagccag
    52561 aggttgtatt ggttggtgct acttctatag gaagagatat agcgcctaga attgcaggta
    52621 aggttggaac aggtctaact gctgactgta caaaacttga aatagattca acagataata
    52681 agttattaca aacaagacca gcatttggtg gaaatttaat ggccactatt gtttgtccaa
    52741 aaaatagacc acagatgtca acagttcgtc caggagttat ggcaaaagct gtaagaaacg
    52801 aatcagagac tggaatttta gaagttgtta ctccagaact tactgaaaaa atgattagaa
    52861 ctagattagt agagatactt ccacaagaaa agaaatctgt aaatctaact gatgctagaa
    52921 taatagtatc agggggaaga ggattaaaaa gagcagaagg atttgagctt ataaaagaat
    52981 tggctgataa attgggggca gagattggtg cttcaagagc agcagtagat tcagggtgga
    53041 tagaacattc tcatcaagtg ggacaaacag gaactactgt tagaccagaa ctatacattg
    53101 catgtggaat atctggagca atacaacatt tagcaggtat gagtgattct aaatatatag
    53161 ttgctataaa taaagatgca aaagccccta tttttagtat atgtgactat ggaatagtag
    53221 gagatttata tgaaattata cctgaaatga tagaatcatt aaataggtaa cttttagaaa
    53281 acattgaata tgtagaatga taagtcttat aatattgtat tgtaagactt attatttttg
    53341 ctgaaggtta tagtggggag atgaaacaat gaaagagcag tggtataagg atatatttgc
    53401 aagagtatta tctatgactg atgatggttt tattgttgta aatacaagtg gagtaataat
    53461 agatattaat gataaatatt gtgacttttt aggaaaagaa agaaaagata taataggaca
    53521 aaatatacaa agtattatac caaatacaaa aatgctagat gttatgaaaa ataagtattg
    53581 tgaagaagga gctatacatc attattcagg tggaaataca aaagaaaaaa gtgtaatagt
    53641 aagtaggtct tatgtggaaa atgacaatgg agaagtagtt gcaggagtag ctcaagttaa
    53701 atttagattg caatcatttg atgtagctaa aaagttaatg tcagaatata tggagctcca
    53761 atattataaa gagcagttta aggataactg tggttttgac aagctcatag gtgaaaatag
    53821 agacttcata gaacttaaga aaacaggtgt gaaagcttct aaaacaaact ttccagtact
    53881 tttaacgggt gaaacaggca caggtaaaga agtttttgct agagcaattc acaataatag
    53941 cagtaggtca gataaaccta tggttagtat aaattgcgct gcaataccag aagaattatt
    54001 agagtcagag ctatttggct atgacgaagg agcttttaca ggagcaaaaa agggtggtaa
    54061 aaaaggtaaa tttttagttg cgaataatgg tacaatcttt ttagacgaga taggtgacat
    54121 gcctttgacc atgcaagcaa aacttttaag agttcttcag gaaagtgaga tagaaccagt
    54181 gggaggtctt aaaactataa agatagatgt aagagtaatc tctgccacaa gaaagaattt
    54241 aagtaaaatg gttgaagagg gattatttag agaagaccta tactatagat taaatgtaat
    54301 aaacattcat atgatggaat tgaaggacag gcaagatgat attttattgc tagcaaatta
    54361 tatattaaac aaattaaatg ttgaatacaa ggaattgaag gttttaagtg ataaggttaa
    54421 aaattgtttt attaactata cttggccggg aaatataaga gaactacaaa atgtaataaa
    54481 aagtgcctat gctgtaagtg atgatatggt cattatgatg tgtgaccttc catctaagat
    54541 ggataatatc agcagagtag ctcaatgtaa tgtggatagc aattgttcaa ttcatgaaat
    54601 ggttgagaat tatgaaaaga gcttaattat tgatgtgtta aggaagtata attggaaatg
    54661 ttctaaggca gcagaggtta tgggaataca caagagtctt ttatataaga aaataaaaaa
    54721 gtatgaaatt gaattaaata attaagataa cttgaattaa ggcaatgcta aaaaagcgcc
    54781 cttattcaaa gcgaactgta taaactgttt tatgcagtta aaacgtgtaa aagtagatgt
    54841 gaagtactaa tgtcaatcat tagtactttt ttattatatt tataattact atctatattt
    54901 cagtatcttt tgatatctaa gattattatg tttaatttag tatataacaa aaccctctta
    54961 gttatggaca gttttttata ttttaactgt ctactaagag gggatagttt agtttaaatt
    55021 tagagtaaat tttatctagc atttataaaa aatattttga atagcttttt tgttatttag
    55081 tcataatttt ctacttcttt atcaagttct ttgccacaag aatcacactt atatatagca
    55141 ttgtatccgt aatcatattc atcaactatt ttcttttgtc taaatacacc accacactca
    55201 cataggaaac caatttttat aagtgtaacg ataaattgtg attttataaa ttttatatca
    55261 ttgcatttat cgttagtgta aaatgtataa atataagagt tatcgcactc atctcttaat
    55321 tcaaatcttt caatatatgt gttatttttt aattcctcaa attcttcttt agttaaatat
    55381 gatttttgtt gcaattcatg taaacgctta atttggtcca ttatttatat cctcccaata
    55441 attttagtat tttaagctta gataaggaat ctaagtttta ttaaatttat cccaaggaat
    55501 tatttaaatc atatttagtt ttattaatta caacatatat aaattacacg aaaataaaac
    55561 taattgtaaa aataatatcc tgtgaaaacc taaactacta accccttact aacccgaaaa
    55621 ctaaaaaaag aaaatatatc caaatataag tgatatataa ataaagatgt ttcatataaa
    55681 tttaacttta aatattctga caataatata tataaatata ttat
//
LOCUS       DAYAOO010000017        53656 bp    DNA     linear   BCT 12-OCT-2024
DEFINITION  TPA_asm: Clostridioides difficile isolate ST8-SSI-h139-18
            SAMN40601845-rid21577343.denovo.017, whole genome shotgun sequence.
ACCESSION   DAYAOO010000017 DAYAOO010000000
VERSION     DAYAOO010000017.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN40601845
            Sequence Read Archive: SRR28438827
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 53656)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 53656)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-MAY-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-MAY-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002157583.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002157583.1
            Genome Coverage       :: 163x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/11/2024 16:19:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 4,038
            CDSs (total)                      :: 3,963
            Genes (coding)                    :: 3,930
            CDSs (with protein)               :: 3,930
            Genes (RNA)                       :: 75
            rRNAs                             :: 6, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 60
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 33
            CDSs (without protein)            :: 33
            Pseudo Genes (ambiguous residues) :: 0 of 33
            Pseudo Genes (frameshifted)       :: 7 of 33
            Pseudo Genes (incomplete)         :: 25 of 33
            Pseudo Genes (internal stop)      :: 11 of 33
            Pseudo Genes (multiple problems)  :: 8 of 33
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..53656
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN40601845-rid21577343.denovo.017"
                     /isolate="ST8-SSI-h139-18"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Denmark"
                     /collection_date="2018"
                     /collected_by="Statens Serum Institute"
     gene            107..703
                     /locus_tag="ACGI5H_001158"
     CDS             107..703
                     /locus_tag="ACGI5H_001158"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889080.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-2 protease family protein"
                     /protein_id="HFG9696871.1"
                     /translation="MLSMNIGEIVASLVGIAMAISIHEFGHAYSAHLLGDDTAKAYGR
                     MTLNPVRHVDPIGLLAMFILKIGWAKPVPVNPNNFKNYKIGNLIVSLAGVFCNVLTAI
                     LCVIINKYVHMYAINTIAEYVFLYSIGFAAFNLLPIPPLDGWGVISTFVPYKWNEYLY
                     KFESMSYIILLIALFTGMYRIILTPIYAVLLKIVYLFV"
     gene            733..1452
                     /locus_tag="ACGI5H_001159"
     CDS             733..1452
                     /locus_tag="ACGI5H_001159"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861170.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="segregation/condensation protein A"
                     /protein_id="HFG9696872.1"
                     /translation="MKYNIQLQVYEGPLDLLYDLITKHKIDIKDISIIDITKQYLNYL
                     KMLDKMDLEITSEFITMASKLLEIKSKYLLYKQKDEEEDPRIELMEKLEEYRKFKVAS
                     QDIKENITYVNERFYRNKEEIIIDDNVDLEDISIEAIKNILPYIFKVKTSQIENANDE
                     KLDKIVRKKIISVEEKILYIRDIIKEKIEVTFTNIIKSYENDEIIATFLSILELIKEK
                     EIVVVQDIFFDDILIRKSSEC"
     gene            1454..1993
                     /gene="scpB"
                     /locus_tag="ACGI5H_001160"
     CDS             1454..1993
                     /gene="scpB"
                     /locus_tag="ACGI5H_001160"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428258.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005515 - protein binding [Evidence IEA];
                     GO_process: GO:0007059 - chromosome segregation [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="SMC-Scp complex subunit ScpB"
                     /protein_id="HFG9696873.1"
                     /translation="MKREDIKYIIESVMFAYGEPISIKELNYIINKELSSKEIEIMLN
                     LLIEEYREQNRGIQIIKLENKYQMCTNKDYAEYIKKIIEPKKKKSLSQATLETLTIIA
                     YKQPITKVEIEDIRGVKCDKVLQTLFENELIREAGRLNKIGKPIIYKTTDEFLKLLNI
                     ESLEELPPIENYQEVATNE"
     gene            2155..2784
                     /locus_tag="ACGI5H_001161"
     CDS             2155..2784
                     /locus_tag="ACGI5H_001161"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889085.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2953 domain-containing protein"
                     /protein_id="HFG9696874.1"
                     /translation="MELNELFNFKYLIIAVIFIISVTMLILISHINILIIADIKNKDI
                     CLKLNIKYMFNLININRQLYPAENSKNNDKKEGMKNNIDSSILLADDLLSIYRLLKKI
                     KIHELYSNINFGTGNIGLTSSVYVLINTLYGNLFNMIDAEKMYLNVNPDFTKDYVLGN
                     IRIHIRPRIKALFNIIIMINKIMNKNKGNKEGDSNESNRFDTESYGNNS"
     gene            2738..3166
                     /gene="ytfJ"
                     /locus_tag="ACGI5H_001162"
     CDS             2738..3166
                     /gene="ytfJ"
                     /locus_tag="ACGI5H_001162"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419458.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005575 - cellular_component [Evidence
                     IEA];
                     GO_function: GO:0003674 - molecular_function [Evidence
                     IEA];
                     GO_process: GO:0030436 - asexual sporulation [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GerW family sporulation protein"
                     /protein_id="HFG9696875.1"
                     /translation="MRATGSIQSLMETTLETIKGSIDANTIIGDPIKTDTTVVVPISK
                     VTIGFGIGGGEYSKGYDDKDREIELKNEKSDTNFAGGSAGAISVQPVAFVVVESGETR
                     IMSLDSNINLVDNILSITPRVLEKIQNISQSNKNQDKNNM"
     gene            3414..3854
                     /locus_tag="ACGI5H_001163"
     CDS             3414..3854
                     /locus_tag="ACGI5H_001163"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419459.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HFG9696876.1"
                     /translation="MSDKELSILLLESMNNFHNLIKIINNERYKKDKVLTERQFFALV
                     KIRKHDKIELKNLSRDLHVSTSSLCILLNKLVEQEYVYREEDSRDRRNTFYGITKNGE
                     KILDNEILKFVSIISDKMDCLDINNKDKLFTSLEESKNIIEQLF"
     gene            3870..5321
                     /locus_tag="ACGI5H_001164"
     CDS             3870..5321
                     /locus_tag="ACGI5H_001164"
                     /EC_number="3.4.11.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902401.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0070006 - metalloaminopeptidase activity
                     [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="leucyl aminopeptidase"
                     /protein_id="HFG9696877.1"
                     /translation="MNIKYSKEILKSLENAITVVALFEGEDVSTTFDKINMISRNFNS
                     KENSIDTVTLVENNNLVNVCLVGFGKRELLNREKIRIIGGNLCKKLKNILKNEAYKSS
                     DVNVLNLNLNSDEIGCFVEGILLGNYKFDKYKTKSKDFERKEVDTITIFTEKEVECQI
                     EKAKILANSTIIARNLVNEPSNVIYPKTLAVETVKLGAEFGFNVDVYEEEKIKALGMD
                     AFFAVSRGSINKPRFIVMRYFGDKESTDILGLVGKGLTYDTGGYSLKSNASMLDMKTD
                     MAGAASVIGAMCAISQSKLKKNVIAVVAACENALSGGSYKPGDIISSMAKKTIEVLNT
                     DAEGRLTLADAIYYIINNEKVTKVVDVATLTGAALILLGNVATPIVTNNDDFYCELEK
                     AATLSGERVWKMPIYDEFKDMIKGEEADLKNTGGKNAGCITAGAFIGEFVGNTPWIHM
                     DIAGTSTSSKSIGYKAKGATGEPVRTLYYLAEI"
     gene            complement(5412..6080)
                     /locus_tag="ACGI5H_001165"
     CDS             complement(5412..6080)
                     /locus_tag="ACGI5H_001165"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896207.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YwaF family protein"
                     /protein_id="HFG9696878.1"
                     /translation="MFKIFLFSSEQFVSLFIFGLFLYYCPKLTKNILPYSYTVEKIIC
                     TLLVIIMALEQLLLISSGNYSTLNSLPIGINYICIYLCIAILIFKQYHLFNIFFSWSL
                     VCSVGELIFSKNLGYEFPSLIYFIFIFSKCLIIYADIYMVDVRKFRVNRYALRDNLAI
                     CFIYFSFIFLLNTFTNSRYYYGFLSHSTTAIFTFIFVTSIMYIPALLFNRDTFILEKK
                     KKSK"
     gene            6349..6489
                     /locus_tag="ACGI5H_001166"
     CDS             6349..6489
                     /locus_tag="ACGI5H_001166"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419462.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9696879.1"
                     /translation="MGIIESASKLAEMVHLLAVEKGITDIEAWDEAVKEYSKIYEERR
                     NE"
     gene            complement(6664..6984)
                     /locus_tag="ACGI5H_001167"
     CDS             complement(6664..6984)
                     /locus_tag="ACGI5H_001167"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428248.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MazG-like family protein"
                     /protein_id="HFG9696880.1"
                     /translation="MKLKTISLPELNNLDPTLESTFIKMGEEQGELAECIGKFRNLSG
                     ENNDLDEVDIIKKTAKELMDVAQTCVTMMFKLEEQYGINLDEIRKEHIKKLEKRGYIK
                     NMDK"
     gene            complement(7104..7841)
                     /locus_tag="ACGI5H_001168"
     CDS             complement(7104..7841)
                     /locus_tag="ACGI5H_001168"
                     /EC_number="2.3.1.286"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419464.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0034979 - NAD-dependent protein lysine
                     deacetylase activity [Evidence IEA];
                     GO_function: GO:0051287 - NAD binding [Evidence IEA];
                     GO_function: GO:0070403 - NAD+ binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NAD-dependent protein deacylase"
                     /protein_id="HFG9696881.1"
                     /translation="MDANSLKDLIANHNNIVFFGGAGVSTESNIPDFRSSTGLFSQKL
                     NKQFTAEQLVSHTFFVRYPEEFFEFYKDKLIYPNAKPNNAHIALAKLEEMGKLKAVIT
                     QNIDGLHQMAGSKNVLELHGSVHRNYCTKCGKFFDLESMLNLGGNIPYCDNCGSIVKP
                     DVVLYEEALDSDVITKTISAISNADLLIIGGTSLAVYPAASFIDYYKGDYIALINKAN
                     TVYDKSASLVINKPIGEVLYEAVLRQI"
     gene            8056..9879
                     /gene="acd"
                     /locus_tag="ACGI5H_001169"
     CDS             8056..9879
                     /gene="acd"
                     /locus_tag="ACGI5H_001169"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861172.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylglucosaminidase"
                     /protein_id="HFG9696882.1"
                     /translation="MKKKAALATLAMLPLGVVNAHADGDIGIVTINYLNVRNEPTAES
                     SIAFVAKKDDKVLIKDSSNGWYKIKAESGQEGWASSKYIAKSNSDSLRTSTNKEKQVI
                     SNSLNMRNGAGTSYRVITVLKKGQKVEVISESNGWSKIKYDGRLGYVSSSYLGDVSNS
                     TNKSKTKQVNTTSLNVRSGPNTSYGLLGKLPKGSKVEVISEGNGWSKIKYNGKDAYVS
                     SMYLSDVSQSNSDNSSQSNDKKNTDKVVNTASLNVRSGPGSTYSKLGKVYKGSKVTVL
                     SESSGWAKINFNNKEAFVVGNYLSTSADTSNNNSNSNSDNSSNSNGNNSSSSGQVNGM
                     SGISGAKIDYKSLSYTLESHISKQVEKAASGGNVIAPSNRKSTPSPEFSTFSAQRTSS
                     FVNASSSDIEYYLNPKNFTNTTKGMMQFLKINSYRDGISESSLNSYLNGLSSSVFKNQ
                     GAAFINAAKKYNIDVVYLVSHAMWETAYGKSTLAQGQTLTSYKGQPLSKPVKVYNFFG
                     IGAIDKSANVSGAEAAYSNGWTSVEATIDGSAKWISQNYVNSSKYNQNTIYKMKWNYD
                     YTWHQYATDVNWANGISGIMENLIGLYGGGSSLVFEVPQYK"
     gene            10094..14392
                     /locus_tag="ACGI5H_001170"
     CDS             10094..14392
                     /locus_tag="ACGI5H_001170"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419466.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003887 - DNA-directed DNA polymerase
                     activity [Evidence IEA];
                     GO_function: GO:0008408 - 3'-5' exonuclease activity
                     [Evidence IEA];
                     GO_process: GO:0006260 - DNA replication [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PolC-type DNA polymerase III"
                     /protein_id="HFG9696883.1"
                     /translation="MESIKEYLDKLEINNSGLGKQLKEVYINRVVYFKEDKIVYFYLT
                     SKDIVSHELLDKFKEELMYKLDYFKDMRMKIRFTGLERKSNKDVIKKYWNNILYILKY
                     LCPSIAGWYKQVEFLCLEEELKIKLPKGIFYERLMKKNVTYVLKTVLSEELGLDLNIT
                     IEKAVDEKVNKERLIRINDREMEEKIRALEIGKVNNCEENEEESYVIKSDVDENLIYG
                     DNANAMIENIVELNASSGTVAVVGDIFDVDTKELKNGKILMIASITDYTSSISCKLFL
                     TDTNKDGVLENVKKGAYLKIKGDIVYDTYQREISMMISGIRKETRIEREDKSEEKRVE
                     LHAHTQMSSMDAICSVKKLVERAAKWGHSAIAITDHGVVQGFPDAMNAGKSNNIKILY
                     GVEGYLVEDDSLIIEDANDKELSQTFVVFDIETTGFSNTNDKITEIGAVKIENFKIVD
                     RFSELINPEKDISYKIQELTGITNELIKDKPTIEEVLPKFMEFVGDSVLVAHNAEFDT
                     GFISQKCREQGLLYNNKKVDTLMLARVMLPNLKRHRLNVVAKELGIPLLNHHRAVDDA
                     EATALIFNKFLQMLTEKGAKTLSDVNNILGKIDYTKLSTNHITLIAKNSIGIKNLYKI
                     ISDAHVNHFFRAPRILRSVLNEYKEGLIIGSACEAGVVFQAVKKNVSDEEMKKIIDLY
                     DYIEVMPIDNNRFMIDKGEVKDEEELRELNRKLIDTAKKFDKIPVATGDVHFLDKHEA
                     VLRKVLKYSQGFKVDEEETYLHFRTTDEMLEEFSYLGEELAYEVVVENSNLIADMVED
                     IKPIPDDTYPPIIEGSDVELREMCYKKAKRIYGDPIPEIVQKRLDRELNSIISNGYAV
                     MYIIAQKLVAKSLSDGYLVGSRGSVGSSFAATMSDITEVNPLPAHYICENEDCKYSFF
                     YEIGEWGSGVDLPDKDCPKCGRKLAKNGHDIPFEVFLGFEGDKEPDIDLNFSGNYQPT
                     IHKYTEELFGEGYVYRAGTIGTVAEKTAFGYARKYVEENNISVPNAEVLRLSNGCTGV
                     KRTSGQHPGGVMVIPDYKDVYDFTPIQYPANDTSCGVITTHFDYHSISGRILKLDILG
                     HDGPTIIRMLEDMTGINITEIPLDDKETMSLFTSTEALGVTPEEINCPIGCLAVPEFG
                     TKFVRQMLLDTKPTTFAELVRISGLSHGTDVWVNNAQDLVREDIVGLKDVISTRDDIM
                     NYLIFKGLPPKMSFTIMESVRKGKGLKPEHIEEMKKNNVPEWYIGSCKKIKYMFPKAH
                     AVAYVMTSFRIAYCKVHYPEAFYATYFTTKVEDFDADLIVKGLDAIKSKINEIESLGN
                     DATTKEKGMLTVLEVALEMYARGIKLLPVDIYKSDATEFIVVGEKTLLPPMAAIQGLG
                     GNAAINIQNERKNGEFISKEDLRKRTKISKTVIETLTNHGSLENMSERNQLSLF"
     gene            14596..15057
                     /gene="rimP"
                     /locus_tag="ACGI5H_001171"
     CDS             14596..15057
                     /gene="rimP"
                     /locus_tag="ACGI5H_001171"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428240.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0000028 - ribosomal small subunit assembly
                     [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA];
                     GO_process: GO:0042274 - ribosomal small subunit
                     biogenesis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome maturation factor RimP"
                     /protein_id="HFG9696884.1"
                     /translation="MKKNLEATIEEIVTKITDEHGFEMVDVEYVKEAGEYYLRVYIDK
                     EEGISLNECELVSRELSPILDEKDPIKENYFLEVSSPGLDRALKKDRDFVRYQGRDVD
                     LKLYKPLNGCKQFEGELVGLTEDNNIKIIANGKEMEFNRKDVAIVRLAIKF"
     gene            15087..16241
                     /gene="nusA"
                     /locus_tag="ACGI5H_001172"
     CDS             15087..16241
                     /gene="nusA"
                     /locus_tag="ACGI5H_001172"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889093.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_process: GO:0006353 - DNA-templated transcription
                     termination [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="transcription termination factor NusA"
                     /protein_id="HFG9696885.1"
                     /translation="MNHEFMEALDELVVDRGIDKEILIDTIEQALLTAYKKNFGSAQN
                     VRVEFDRDKGDIKVFSQRVVVDESDLYDTFLEIELADAREINPNYELGDIIEHEVTPK
                     NFGRIAAQTAKQVVVQRIREAEREIVYNEFIEKENEIVTGEVARANKNVVYVNLGRIE
                     GIMTQSEQIPFENYKAGQKIKFYILEVKKTNKGPQIVVSRSHPGLVKRLFEEEVPEIY
                     EGIVQIKSVAREAGSRTKMAVRSIDEKIDPIGACVGPKGLRVKNIVDELGDEKIDIIK
                     YSEDPAEFISAALSPSKVVRVDIDEDEKSALVIVPDYQLSLAIGKEGQNARLAAKLTN
                     WKIDIKSESQAEQEMLNLENSKEIEAEDVEAEFIDQEELDTSEDNFSEEE"
     gene            16248..16529
                     /locus_tag="ACGI5H_001173"
     CDS             16248..16529
                     /locus_tag="ACGI5H_001173"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="YlxR family protein"
                     /protein_id="HFG9696886.1"
                     /translation="MILKKVKKVPQRKCIACQDRDSKKELIRIVKNKEGKIFLDPTGR
                     ANGRGAYVCKSSECLKKAIKSKALNKAFKIDVPDEVYDNLLMELEEYEK"
     gene            16519..16830
                     /locus_tag="ACGI5H_001174"
     CDS             16519..16830
                     /locus_tag="ACGI5H_001174"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419470.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L7Ae/L30e/S12e/Gadd45 family ribosomal protein"
                     /protein_id="HFG9696887.1"
                     /translation="MKNNKEKVLSFLGLATRAGKIVSGDDSTLLDLKKGKVNLILIAE
                     DASNNTKKLFKDKSTFRNIPYLFFSTKEEIGFAIGKSPRAVVGIKDENFSKKIIELIE
                     I"
     gene            16852..18792
                     /gene="infB"
                     /locus_tag="ACGI5H_001175"
     CDS             16852..18792
                     /gene="infB"
                     /locus_tag="ACGI5H_001175"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438306.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0003743 - translation initiation factor
                     activity [Evidence IEA];
                     GO_function: GO:0003924 - GTPase activity [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_process: GO:0006413 - translational initiation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="translation initiation factor IF-2"
                     /protein_id="HFG9696888.1"
                     /translation="MSKTRVYQIAEELNISNEELINKLAELDINVTDKDSVLEGEELE
                     LALEMLGEDLSQENGNVIEIDGKLTVQVLATKLDKSPSEIIMKLMKMGTMATINQEIS
                     FEIAALAAKDYGFELTVAESDDTEALEIEALMEIEEDKEEDLKPRPPVVTVMGHVDHG
                     KTSLLDAIRKTDVISGEAGGITQHIGASEVKINGHKIVFLDTPGHEAFTSMRARGAQV
                     TDIAILVVAADDGIMPQTVEAINHAKAAGVPLIVAINKIDKPGANPDKVKQELADQGL
                     LVEDWGGEVIAVPVSAKKKEGIDTLLEMVLLVAEMEELRANPNKRAVGTVIEAELDKG
                     RGPVATVLVQGGTLTVGDPIVAGVACGKVRAMINAKGKRVKTAGPSTAVEILGLSEVP
                     QGGDQFVEVPTDKIARSVAARRQQIVRDEMLKSTQRLSLDALFSQMSEGSIKDLNIVI
                     KADVQGSVQAVKQSLEKLSNEEVQVKVIHGGVGAVTESDILLAAASNAIIIGFNVRPV
                     PGAESLGEKENVDIRTYTIIYKAIEDIQAAMTGMLDPEYVDEETGKAEIREIYKISGV
                     GTVAGCYVTNGKIFRNCKVRLVRDSIIIHEGELAALKRFKDDVKEVNSGYECGMSFVN
                     YNDIKEGDIVEAYITKEVERKL"
     gene            18835..19215
                     /gene="rbfA"
                     /locus_tag="ACGI5H_001176"
     CDS             18835..19215
                     /gene="rbfA"
                     /locus_tag="ACGI5H_001176"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0006364 - rRNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosome-binding factor RbfA"
                     /protein_id="HFG9696889.1"
                     /translation="MASYNRTRRIAEEIRKVVSTMLINGVKDPRITSMVSVTDVEVTN
                     DLRYAYVYVSILGGDEESTLTGLKSAGGYIRREVGKNIKLRYIPEIVFKLDDSIEKGM
                     YMDSLIKRVNEKNAQQNEDENYDE"
     gene            19196..20179
                     /locus_tag="ACGI5H_001177"
     CDS             19196..20179
                     /locus_tag="ACGI5H_001177"
                     /EC_number="3.1.3.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438308.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003676 - nucleic acid binding [Evidence
                     IEA];
                     GO_function: GO:0004527 - exonuclease activity [Evidence
                     IEA];
                     GO_function: GO:0008441 - 3'(2'),5'-bisphosphate
                     nucleotidase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional oligoribonuclease/PAP phosphatase
                     NrnA"
                     /protein_id="HFG9696890.1"
                     /translation="MKIMMNNMDSIINYIYEGDYFIVTSHISPDGDNIGSTLSMYYTL
                     KNLGKNVYYVLDDEAPLNLRFLVEDVKIYKSNEFNMKNYSLIALDCGDKMRICVSDEI
                     KNNASKLICIDHHASNDSYGDLNYVDIDASSTCELVYNLLVRFQQIKDINIINEDIAT
                     CLYTGLVTDTGNFSYSNVHASSFEMAKNLLVLGAQKNTIIQNIYQSNSSGYYKLLGEA
                     LKGLEIFDSKVSSIVLTQDMMNRNNISFNDVDGITTYTRDIKGIEVGILFKEKKQNEI
                     KVSFRSKNYVDVSEIAKLFGGGGHVRAAGCTIRDSIDNAKKMVLEAVLKSI"
     gene            20192..21097
                     /gene="truB"
                     /locus_tag="ACGI5H_001178"
     CDS             20192..21097
                     /gene="truB"
                     /locus_tag="ACGI5H_001178"
                     /EC_number="5.4.99.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896221.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0009982 - pseudouridine synthase activity
                     [Evidence IEA];
                     GO_process: GO:0001522 - pseudouridine synthesis [Evidence
                     IEA];
                     GO_process: GO:0009451 - RNA modification [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA pseudouridine(55) synthase TruB"
                     /protein_id="HFG9696891.1"
                     /translation="MNKIISILKPTGMTSHDVVSRVRKILNIKKVGHTGTLDPDASGV
                     LPICIGKATKVCEVILNKDKSYICELTLGISTDTYDASGEILKKVDDFKFSNEDIERA
                     FDTQRGEINQLPPIYSALKVNGKRMCDLVRSGRQSEITLKTRRVNIKDIKILSIKGNK
                     VMFYVECSKGTYVRSICHDIGEYLGCGAHMSFLNRTSSGKFDLDNSITLEELELFYEN
                     KTLDKYLYDIDYVLDSFNYVVLNPNAIKYYSNGGSIDDKRFLKNNFDKDDEFVRVYST
                     DNFLGLGKLSKHNNTISVKSDKMFI"
     gene            21228..22157
                     /locus_tag="ACGI5H_001179"
     CDS             21228..22157
                     /locus_tag="ACGI5H_001179"
                     /EC_number="2.7.1.26"
                     /EC_number="2.7.7.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889098.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003919 - FMN adenylyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional riboflavin kinase/FAD synthetase"
                     /protein_id="HFG9696892.1"
                     /translation="MVIIKSIKEIANIKESVITIGNFDGVHKGHQVLIGKTVEHAKKE
                     NIQSIVFTFANHPVNYFRPNSTKNIISNDDKIKLLEDLGIDIVVIIPFDEYMTKIPAK
                     DFVDEILVKKLKAKKIVIGHDFTFARAKEGNVNLLKSLEHEFGFEVEVIKPIKINDVR
                     VSSTYIRSLVSQGDMANVKEYLGRNYKLEGCVIHSKHLGRTIGFPTANIDLKNNMLVP
                     KRGIYASIVHIGDETYFGATNVGYNPTVNGKTLSIETNILEFDRDIYGENIIVEFLER
                     IRDERKFNSIDDLKNQLYNDTNYVYENYVCKNK"
     gene            22261..22518
                     /gene="rpsO"
                     /locus_tag="ACGI5H_001180"
     CDS             22261..22518
                     /gene="rpsO"
                     /locus_tag="ACGI5H_001180"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002843739.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S15"
                     /protein_id="HFG9696893.1"
                     /translation="MINKSEIIKEYGRAEGDTGSPEVQIALLTARINELNGHLKTHKK
                     DHHSRRGLLKMVGRRRNLLAYLKEKDLEGYRALIAKLGLRK"
     gene            22758..23603
                     /locus_tag="ACGI5H_001181"
     CDS             22758..23603
                     /locus_tag="ACGI5H_001181"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419493.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DegV family protein"
                     /protein_id="HFG9696894.1"
                     /translation="MKIKLVCDSLCDIPDEISEKDYIEIVPLTVIFNDREYIEGVDIK
                     KEEFYKKVKEIKQIPKTSQATYMEFKEVFDKFITEGYHIICMTGAANASGTFQSAMIA
                     KNDVNENEKIHIFDTRNLSLGSGQYVIKACELLEEGLGFEEIIDELENTRSSVRLLFA
                     PYTLDFLKQSGRVPVATALIGNMLNIKPIFFFDNGEAKLVNKVRGIKNIASKLVDIIL
                     EMNEGSLEGKIVTIGCGDNLHDCEILKDEVNKRIKARRVLFTRGGVSICSHTGPDILA
                     ISCSN"
     gene            23728..25839
                     /gene="pnp"
                     /locus_tag="ACGI5H_001182"
     CDS             23728..25839
                     /gene="pnp"
                     /locus_tag="ACGI5H_001182"
                     /EC_number="2.7.7.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438316.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0004654 - polyribonucleotide
                     nucleotidyltransferase activity [Evidence IEA];
                     GO_process: GO:0006402 - mRNA catabolic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="polyribonucleotide nucleotidyltransferase"
                     /protein_id="HFG9696895.1"
                     /translation="MFEHKIFKMDFAGRELSVEIGKICEMASGSCIVRYSDSMVMVNT
                     TKSAKPRDGIDFFPLSVDYEEKLYSVGKIPGGFLKREGKPSEKAILTSRLIDRPIRPL
                     FPKGFRNDVQVVATVLSVDQDCTPDIVAMIGSSIALSISDIPFNGPTGSVCVGLVDGA
                     FVVNPNAEQREKSSMHLVVSGTKEAIMMVEAGADEVPDEVMLDAILFAHQEIKKIVEF
                     IEGIVAEVGKEKMPVELYHAGEEITQLVREFATDKMKKAVQTFEKLERMENMDRVKEE
                     TLAHFEETLEDFEDFVGDIEEVLQDIIKEEVRKLIVHENVRPDNRKLEEIRPIWCETG
                     MIPRAHGSAIFTRGQTQVLNVATLGALGDVQKLDGLDEEENKRYMHHYNFPAYSVGEA
                     RPSRGPGRREIGHGALAERALLPVIPSQEEFPYAIRLVSEVLSSNGSTSQASVCGSTL
                     SLLDAGVPIKDMVAGIAMGLIKHDGKVAVLSDIQGMEDHLGDMDFKVAGTEYGITAIQ
                     MDIKIDGIDKEILQRALKQAKEGRIHILGEMRKTISQPKPELSPYAPKIVKMQINPDK
                     IKDVIGPGGKIITKIIDETGVKIDIEQTGEVFISGIEIDMIKKAQELINNIVVEPEVG
                     KTYKGKVSRIMNFGAFVEILPGKEGLLHISHIAHERVAKVEDVLNIGDEVEVKVTEID
                     EKGRVNLSRKVLLPKPEHKNK"
     gene            26105..26848
                     /locus_tag="ACGI5H_001183"
     CDS             26105..26848
                     /locus_tag="ACGI5H_001183"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419498.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016810 - hydrolase activity, acting on
                     carbon-nitrogen (but not peptide) bonds [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide deacetylase family protein"
                     /protein_id="HFG9696896.1"
                     /translation="MIMMVLNKSKLKKIIILILVVLLVLSGGVMVLKLFNNKPVFNLF
                     NGVDLPYERGTKDKSGYVALTCNIDLGWETEYVESILETLKKENVKITFNVTGKWAEK
                     NKDELLKIKKQGHEIGNHGYKHLDYSTLSYEDNYEQIETSKKIIEEIIGEKTKFFQAP
                     AGSFGPETVKAAKALGYTSIKWDADTIDWKYKDQPEVIIDRMKKKDIKDSSIILMHPT
                     NATTKCIDDIIAIVREKGLKAGKLSDVFK"
     gene            27006..28253
                     /locus_tag="ACGI5H_001184"
     CDS             27006..28253
                     /locus_tag="ACGI5H_001184"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428227.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="M16 family metallopeptidase"
                     /protein_id="HFG9696897.1"
                     /translation="MYKTKILENGLTIIGEEIPYLKSITLGIWINAGSRIEEAQVSGT
                     SHFIEHMMFKGTKNRTSKEIASSIDNLGGQINAFTSKECTCYYVKLIDEHIDTGIDVL
                     SDMILNSKFDKNDIDKERLIILEELKMYEDSPDDLSYDLLVENIYANDGLGMNIIGTK
                     ESLYNITRESMLEYLNKYYIPNNAVISIAGNFNFDDMVEKIKSKFGHWEKKNLSIDIS
                     EAKFNPCFISKNKDTEQVNLAMCLKGIPFENDEEVYSMAVVNNIFGGSISSRLFQKIR
                     EEKGLVYSIYSSQTLYRKCGELGIFASMSTENLQDVYNLIKKEIENIRENYLTEKEIS
                     ESKEQLKGNYILDLESTSSRMMSTGKSMLLSKKVKTTDEILECINSVNINSIKKVVDK
                     VFNIENIGTCIVGRDVEKILHLD"
     gene            28288..28533
                     /locus_tag="ACGI5H_001185"
     CDS             28288..28533
                     /locus_tag="ACGI5H_001185"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419503.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003674 - molecular_function [Evidence
                     IEA];
                     GO_process: GO:0030436 - asexual sporulation [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="YlmC/YmxH family sporulation protein"
                     /protein_id="HFG9696898.1"
                     /translation="MNLSEIAGKEIVNLVTGERLGVIGECDLILDETTGGILALLIPK
                     EKGFFARRKDKSFLEVPWRNVKKIGNDMIIIEYEGYI"
     gene            28543..29766
                     /gene="dapG"
                     /locus_tag="ACGI5H_001186"
     CDS             28543..29766
                     /gene="dapG"
                     /locus_tag="ACGI5H_001186"
                     /EC_number="2.7.2.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419506.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004072 - aspartate kinase activity
                     [Evidence IEA];
                     GO_process: GO:0009089 - lysine biosynthetic process via
                     diaminopimelate [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate kinase"
                     /protein_id="HFG9696899.1"
                     /translation="MSILVQKFGGTSVESYEKMNEVCKIVKAYKKNDEELQLVLVVSA
                     MGRKGAPYATDTLINLCSAVNDEPSKRELDLIMSCGEIISGTILANLLNAQGIDSVFF
                     TGQQAGIITSDEYSNAKIKYINPKKVKRALDDGKVVVIAGFQGVTDDGEITTLGRGGS
                     DTSAVAIGKALECETVEIYTDVDGIMTADPRVEPNAKVLSFIDYEEVFQMADKGAKVI
                     HPRAVQLAKSGNITLAIKNTMNPTFEGTKIGSLCRHLEDNIEYEQERDFKVAVANKDS
                     VAQVKIKSAEEVFTEVLNEIEKKLITIDMINFFISEKAFVVEDADIKSLKEILDKFEL
                     DYEVNRDCAKVTLICSRIADEMSGIMSKVVRGLSKAGVSLLQTSDSNMTISCLVSEED
                     MHTAVHAIHQQFYLK"
     gene            29879..30613
                     /locus_tag="ACGI5H_001187"
     CDS             29879..30613
                     /locus_tag="ACGI5H_001187"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433325.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp protease proteolytic subunit"
                     /protein_id="HFG9696900.1"
                     /translation="MKDYREDNERFDKDNCSEESSCEERECIKQFGTNEMPPQPPKDI
                     QCITIIGEIEGHFIGNPQKKATKYEHIIPMLYSIEESNDVKGVLVVLNTVGGDIEAGL
                     AIAELLNSTSKKVVTLVLGGSHSIGVPLATAGDYSFIAPTATMIIHPVRTTGLVIGIN
                     ETFEYFKKMQDRIIQFIIRTSNIKKDVLEKLMHEKDELVSDVGSVLIGKEAVDYGLID
                     EVGGLKEALKKLRELIKESEEEKNND"
     gene            30736..33147
                     /locus_tag="ACGI5H_001188"
     CDS             30736..33147
                     /locus_tag="ACGI5H_001188"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889104.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA translocase FtsK"
                     /protein_id="HFG9696901.1"
                     /translation="MATKKKKKKKVNTLSFNAEYHNLITIFIGVFLLYSLNSNSMGWI
                     PVLMQNLFKGLFGGLSIAIPFIVIITGLLGFFDGNEYIYRLRKTKLYYIIILFIFVFY
                     GLLNAGTLPVDSPLKGNMFDDVMKLGVSGQGSGLIATTIAYYMSKIFGIAGGWLISIF
                     ALILSVMFIFNISIKDLVSNAKSKSKASKDSNLTFKDKIANMKKSAIDMMTDEVDDTT
                     INKKPGFFKGLMSKGLNNDDEEDEYFEEENSDGVDDKTIKIVGFNKAEDEYLEILEGT
                     QSMPELDVLKELQKATNENPVVDTKPEKKVDIAKPNLNIEKTQPMSIVAEPVNEDYSN
                     YKKPSIELLNKVNKKSDENGKKKVLKNASLLEKTLSDFGVEAKINQVTVGPTITRYEI
                     QPSPGVKVSKIVNLTDDIALSLAAKSIRIEAPIPGKSAIGIEVPNEEAQMVGVREVLE
                     SEEFNNFNSPLAMGLGKDVAGKIIIGDIGKMPHLLIAGSTGSGKSVCVNTLISSILYK
                     ANPDEVKLLLIDPKVVELANYNGIPHLLIPVVTDPKKAANALNWAVTEMNRRYKLFAD
                     AQVKDVTSYNEKAEEKLPKIVIIIDELADLMMASANDVEDYICRLAQMARAAGMHLIV
                     ATQRPSVDVITGVIKANIPSRIAFAVSSQTDSRTILDMGGAEKLLGKGDMLFYPLGAA
                     KPVRLQGAFISESESEKVIDFVKSQVKDGIKYEEDIIETISKVNTSKGSDEDEFLSEA
                     IEFVVESGQASASMLQRRFKIGFNRAARLIDSMEERGIIGASEGSKPRKVLISKQDLQ
                     NLEGE"
     gene            33150..34208
                     /gene="mnmH"
                     /locus_tag="ACGI5H_001189"
     CDS             33150..34208
                     /gene="mnmH"
                     /locus_tag="ACGI5H_001189"
                     /EC_number="2.5.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889105.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA 2-selenouridine(34) synthase MnmH"
                     /protein_id="HFG9696902.1"
                     /translation="MSVIKIEKALKLDKVIFVDVRTEGEYEEDHILNAINMPLFKNNE
                     HNDVGTIYKMQGKHEAIQKGFDYVSYKLKDIYLQAAELALNYDNIVIYCARGGMRSGS
                     IVNLLSSLGVNVYQLEGGYKAYRNFVLEYLRHVMDTKNFVSVHGLTGTGKTDLLHLLD
                     EKGIDVLDLEGIAKNSGSTFGFITFDKKPPSQKNFETKLFESIFFSKENYIFVESESK
                     RVGSVTVPNEIFEAMTREGHHILLECDIENRVDRLCRDYIYDKDEGNILILKECINKF
                     RKRLGNKVVDDYIDLLESGEYKELVKRYLLEYYDPLYMHSVEKYKYSKIINFNDTQKA
                     LEDVIDLYESILEGESEC"
     gene            34202..35536
                     /gene="rimO"
                     /locus_tag="ACGI5H_001190"
     CDS             34202..35536
                     /gene="rimO"
                     /locus_tag="ACGI5H_001190"
                     /EC_number="2.8.4.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438333.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0008172 - S-methyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:0016740 - transferase activity [Evidence
                     IEA];
                     GO_function: GO:0016782 - transferase activity,
                     transferring sulphur-containing groups [Evidence IEA];
                     GO_function: GO:0051539 - 4 iron, 4 sulfur cluster binding
                     [Evidence IEA];
                     GO_function: GO:1904047 - S-adenosyl-L-methionine binding
                     [Evidence IEA];
                     GO_process: GO:0018339 -
                     peptidyl-L-beta-methylthioaspartic acid biosynthetic
                     process from peptidyl-aspartic acid [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S12 methylthiotransferase
                     RimO"
                     /protein_id="HFG9696903.1"
                     /translation="MLKIALESLGCSKNLVDAEIMMGILNNKGYKLIGDFEEADVIIV
                     NTCGFIESAKQESIDTIINFAELKKTGNLKLLIVTGCLAQRYSEELKTEIPEIDAIVG
                     TGSYQNIDKILKELSEMHKIVSLNDIEFVFNEDLPRYISTPSYMAYLKIGEGCSNNCT
                     YCIIPKLRGKYRSRKFEDIIKEAKKLAESGVKELVVIAQDTTKYGFDLYGKERLSELL
                     EELAKIDGFKWIRVMYSYPESITEELIQVIKKYDNICSYFDMPIQHASNNILKLMNRK
                     TTKEDILNKINLIRSNIPDAILRTTIIVGFPGETEDDFKQLVDFVEEVKFDRLGAFAY
                     SREEDTPADRLPNHIDEEVKIQRRDTLMMIQQKISEELNDKKIGKTYEVLIEEQIEDN
                     VYTGRTQGDAEEIDSIVYVKSVDNLEVGEFVSVQINDAMEYDLMGDVLYELA"
     gene            35523..36065
                     /gene="pgsA"
                     /locus_tag="ACGI5H_001191"
     CDS             35523..36065
                     /gene="pgsA"
                     /locus_tag="ACGI5H_001191"
                     /EC_number="2.7.8.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905407.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0008444 -
                     CDP-diacylglycerol-glycerol-3-phosphate
                     3-phosphatidyltransferase activity [Evidence IEA];
                     GO_process: GO:0008654 - phospholipid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="CDP-diacylglycerol--glycerol-3-phosphate
                     3-phosphatidyltransferase"
                     /protein_id="HFG9696904.1"
                     /translation="MNLPNKLTLFRIFLIPVFVLIMLLNIPNKFLIACIIFIIASITD
                     ALDGKIARKYNLVTDFGKFMDPLADKLLVISALTCMIEDHLVSSWMVIIIVARELTVS
                     ILRAIAAADGKVIAAGNSGKLKTITQMVSIVFLLLGAQFENVLILNIGEILILIATLL
                     TLYSGWEYLYKNKELFMSSK"
     gene            36353..37399
                     /gene="recA"
                     /locus_tag="ACGI5H_001192"
     CDS             36353..37399
                     /gene="recA"
                     /locus_tag="ACGI5H_001192"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428218.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003697 - single-stranded DNA binding
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0008094 - ATP-dependent activity, acting
                     on DNA [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase RecA"
                     /protein_id="HFG9696905.1"
                     /translation="MSVDQEKLKALNEALGKIEKDFGKGSVMKLGEATSMSIDVISTG
                     AIGLDIAIGIGGLPRGRIVEVYGPESSGKTTVALSCVASAQKDGGIAAFIDAEHALDP
                     VYAKALGVDVDNLIISQPDTGEQALEIAEALIRSGAIDIIVIDSVAALVPKAEIDGDM
                     GDSHVGLQARLMSQALRKLTGSIKKSNCVAIFINQLREKVGIMFGNPETTTGGRALKF
                     YSSVRLDVRKIDTIKQGDKVIGSRTRVKVVKNKVAPPFKQAEFDIMYGEGISKIGDLL
                     DIAADVDIVKKSGSWYSYNDTKLGQGRENVKKFLEDNLDLTTEIDEKVRAFYNLNEEH
                     EESGTSVSKEIVEE"
     gene            37575..39116
                     /gene="rny"
                     /locus_tag="ACGI5H_001193"
     CDS             37575..39116
                     /gene="rny"
                     /locus_tag="ACGI5H_001193"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428216.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_process: GO:0006402 - mRNA catabolic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease Y"
                     /protein_id="HFG9696906.1"
                     /translation="MDVIDSVVMIVIGAAVGIIAGYFVRKNISEAKIGQAENLAKEII
                     DKAHHDSETVQKEKLLEAKEEIHKWRTEAERENRERRTEVQKYEKRVVQKEEVLDRKL
                     QNLESKEVNLSEKLKVVEKKEEEVEVIKTQQLEKLESISGITSDKAKEIILTNAERDV
                     RREMSIMIKEIESQAKEEADKKSREIIGYAIQKCAADHVAETTVTVVSLPNDEMKGRI
                     IGREGRNIRTLETLTGIDLIIDDTPEAVILSGFDPIRREIARIALEKLIADGRIHPAR
                     IEEMVEKARKEVDNIIKEYGEQAAFETSVHGIHPELIRLLGRLNYRTSYGQNVLKHSI
                     EVAHIAGIMAAEIGADIRLAKRAGLLHDIGKAVDHEMEGTHVEIGMDLLRRYKESKEV
                     IHAMSTHHGDYEPQTVEAVLVTAADAISAARPGARRETLEAYIKRLEKLEEIANSYEG
                     VEKSFAIQAGREIRIMVKPEAINDEEIHLLARDMTKKIEDELEYPGQIKVSIIRETRA
                     IEYAK"
     gene            39430..41766
                     /locus_tag="ACGI5H_001194"
     CDS             39430..41766
                     /locus_tag="ACGI5H_001194"
                     /EC_number="2.7.7.65"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438341.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0009975 - cyclase activity [Evidence IEA];
                     GO_process: GO:0009966 - regulation of signal transduction
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="diguanylate cyclase"
                     /protein_id="HFG9696907.1"
                     /translation="MKKNTLLHTNIMVCIIITLGFVATSIIGYQSNTNIFKNDIEHVS
                     TLAAEGIYYQIDKLLSEPINVSLTMANDSLLKNFLDGEKEHLNDEEFIYKLQDYLNVY
                     RNKYSYDSVFLVSTKTNNYYHFNGLDRNLSANNSENQWYYTFLKNDDEYSLNVDNDEA
                     SNNSITVFVNCKIKDDNGATMGIIGVGLKVNSLQMLLKGYNDKFDVVARLIDDKGFVQ
                     LAVDKTGHENINFFENSSSDLSNSKQLILNNKKEQKSFWYSSEKSKSYIVCQYIPSLK
                     WHLVLENDFTLMIKQLHLQFFKGIAVIVLIIIFVLFTITHVLKKYKNQIIKLSVSQKL
                     EYQKLLSKSTEGLYENIFEIDITNNKAGCEDENRYFHEFGLGLNTPYDEALHTIAKNQ
                     IKEEYAQGYLDTFLPENVIKRYNSGINNISYDFLIKKDEESYHWIRINARIFFWTSDE
                     SVRMISYRKNIDEEKNRELLLLERSQRDSLTGLYNKATTEEFIRSFLKNESNQDLEHV
                     FLIFDIDNFKNVNDKYGHVFGDFVISEFALELKSQFREDDIVGRIGGDEFVVLIKDFN
                     NNNYVLIDKLERFCSKINQKKFVEQAEFSIACSIGVAMYPEHGYVYSELYEKADQALY
                     YAKSHGKNSYHIFSEDSIDSISFHIDSRDIKVLLEMATDGVVKFACMENLKLLYFNQK
                     MLEFTGYSAQTVTSIGFDIFSPVLQDDLQMVLDTLREAISKRETFEIVFRFCHTDGHI
                     FPVRMQGKFVSELYQNRYPVFYAIYTDISSINTLLENK"
     gene            42148..43929
                     /locus_tag="ACGI5H_001195"
     CDS             42148..43929
                     /locus_tag="ACGI5H_001195"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438344.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="UvrD-helicase domain-containing protein"
                     /protein_id="HFG9696908.1"
                     /translation="MSQYININSQLDALKLKEFEKIFYENINEDVKVVPKVTPFKGIN
                     TDLLYVKDGRILFIKFMDTTEDIFFILEEELLEVMNEEYELLKLKMGQKNRNISYNYV
                     YIMPYVEVEETYEFEEFVNNNIIDKNKLQDIMNKGSLEEYLNDENDEINLNLFLLDIC
                     SEYYIINDKLHLNEKFKKISFYNDDYKYTATMMEDVQIKDVVSIKYGNTLIEGGSGIG
                     KTAIMLSRAIKLAKVYPHHKLVIFTHTKQLCNELRERIELLYKDNNNLEVHTFSSFIF
                     KLAKKFNLIVDYNMLKNDYEKTFNNLVKQAQNIIKNKNMFKAIFIDEAESFLEYEIDF
                     IREFLYKTKFIFNVCSCNSLNISNRLNIFKKLYNGIEFDDKIILSKNYRQAKEIVDFT
                     NKFSNNSNSYINELRPNTEFSTFFYTKALRGGNKSVDIIKVSDLDDQISSVIWEIEYL
                     ISKKGLDYSEVAIVYPYNKKKLKSGKTIYFQYMLKKALEEAKIPYICAEDNLTNISKK
                     VGTTIANIYAIKNLEYKAVIVCELEMLYNQTINDIEQDYQVNDFVGDLNKVYLAMSRA
                     TDYLSIVTTFNEEASDIIRLITESKDI"
     gene            complement(44011..44541)
                     /gene="lepB"
                     /locus_tag="ACGI5H_001196"
     CDS             complement(44011..44541)
                     /gene="lepB"
                     /locus_tag="ACGI5H_001196"
                     /EC_number="3.4.21.89"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729595.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0004252 - serine-type endopeptidase
                     activity [Evidence IEA];
                     GO_process: GO:0006465 - signal peptide processing
                     [Evidence IEA];
                     GO_process: GO:0009306 - protein secretion [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="signal peptidase I"
                     /protein_id="HFG9696909.1"
                     /translation="MSVKKEIFDWIKSIAMAIVLAFVILQFIRPSIVSGESMYPTLDD
                     KDYLILNRISYKVGKPEKGDIVVFKTNLVDGETGKKKDLIKRVIATEGDRIKISNSKV
                     YVNGKLLNEPYIHNNYTSGDIDTVVPKGKLFAMGDNRENSNDSRFPDVGMVDEDEVLG
                     KVMVRLLPLDNIGKVD"
     gene            complement(44581..45405)
                     /locus_tag="ACGI5H_001197"
     CDS             complement(44581..45405)
                     /locus_tag="ACGI5H_001197"
                     /EC_number="3.6.1.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438350.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0050380 - undecaprenyl-diphosphatase
                     activity [Evidence IEA];
                     GO_process: GO:0016311 - dephosphorylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="undecaprenyl-diphosphate phosphatase"
                     /protein_id="HFG9696910.1"
                     /translation="METFSLLEIFKAVILGIVQGITEWLPVSSTGHMILVDEFIKLNF
                     SNTFISTFLVVIQFGSILAVLVIFFRKLNPFDSAKNIKQKKETVRLWLKVIIAVIPSG
                     VIGILFEDDIDRLFFNSTVVAIALIVYGIIMIGLEKRNKKPKYKDFSQVTYKLALCIG
                     LFQCLALIPGTSRSGSTIIGAVLLGTSRYVAAEFSFFLAIPTMLGASALKLLKAGFGF
                     TGFEWLILGVGSVVAFVVSIVVIKFFMDYIKKHDFKVFGYYRIVLGIVVLAYFFLL"
     gene            45662..46570
                     /locus_tag="ACGI5H_001198"
     CDS             45662..46570
                     /locus_tag="ACGI5H_001198"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889110.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HFG9696911.1"
                     /translation="MYSTKILDDYEYETFNVFSTKLNPNTKHDYLSKVILFKEFLKGK
                     ELIYATKEDCKNFVDYIQTKYAKSTCEKIYSYLHSFYNFLKKEGYIDINPFRYVEKPT
                     VTRIKTKDDVLSIQEINKLIGILPKLNIRDRVIIVCLVTTGCLLNELVSLKWKDLMVD
                     ENDNSYVRLGKGRKERVVKLHPYFFKLLEDYRNYSGLPEVIIPSDDFIFTTQKSNSIT
                     DRNVRLIVKKALDLAGLSQYSARDFRHSFAAISLRLGADESDVKNQLGWSDKYYAIRY
                     KYVLNFVDSEIVDYLIEKDNLDINKK"
     gene            46714..48159
                     /gene="purB"
                     /locus_tag="ACGI5H_001199"
     CDS             46714..48159
                     /gene="purB"
                     /locus_tag="ACGI5H_001199"
                     /EC_number="4.3.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419557.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004018 - N6-(1,2-dicarboxyethyl)AMP
                     AMP-lyase (fumarate-forming) activity [Evidence IEA];
                     GO_process: GO:0009152 - purine ribonucleotide
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="adenylosuccinate lyase"
                     /protein_id="HFG9696912.1"
                     /translation="MIDNKYTTYSNPLTDRYCSKDMSYIFSPQFKFSTWRRLWVALAE
                     GEHELGINITEEQLDELRANIDNINFDEARKIEKEVRHDVMSHVKAYGLQCEKAKGII
                     HLGATSAYVGDNTDVIQMNEALKLLRVKLVNLINNLKEFALKYKDMPALGFTHFQAAQ
                     LTTVGKRACLWAQDLILDLEDLNYRIDNMKLRGVKGTTGTQASFLSLFEGDHEKVKEL
                     DKKICKKMGYHSSYAVSGQTYTRKLDYQVISILSGIAQSMHKMTNDIRLLQSLKELEE
                     PFEKNQIGSSAMAYKRNPMRSERIASLSKYIISESISPAMVQATQWLERTLDDSANKR
                     LAIPQAFMAADAILEIGINVTDGLVVYENMINRRVNEELPFMATETILMEAVKRGGDR
                     QELHEIIREYSMKAAYRVKHEGKDNNLIELIMNDDSFKMSKEEILSIMDPKNFIGRAP
                     EQVVEFVNEVVEPAIKDYKEDLGKVDVDLRV"
     gene            48470..48922
                     /locus_tag="ACGI5H_001200"
     CDS             48470..48922
                     /locus_tag="ACGI5H_001200"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HFG9696913.1"
                     /translation="MNYIVKDTISFLVKTFPKIYSSLYLEDLKKFAPDYNVNKTQLRA
                     LVFIKNYGVISMTDLCSKLNIEKGSLTSMVDDLTDKKYVTRKRDLVDRRKYLIDITEE
                     GDKIATDFMDKLSDGLGEKLSKLTEEDRKKYLEAINTLQYILNKEEFR"
     gene            complement(49257..50453)
                     /locus_tag="ACGI5H_001201"
     CDS             complement(49257..50453)
                     /locus_tag="ACGI5H_001201"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal phosphate-dependent aminotransferase"
                     /protein_id="HFG9696914.1"
                     /translation="MNYSNRVSAMQASPIRKLVPFAQAAKDKGIKVYHLNIGQPDIKT
                     PKGFFDAVKNFDSEVLEYATSEGIPELLEALQNYYKTYDMNFEKDELLVTNGGSEALL
                     FTMMAVCDPGDNLLVPEPFYTNYNGFGQSVNVEVNAVTTKAENGFHLPSKEEILSKVD
                     DKTKAIILSNPGNPTGAIYTKEELNILAEIAKEKDLWIIADEVYREFVYDGLEYTSCG
                     NLEGVQDRVIIIDSVSKRYSACGARIGSIACKNKGLIAQILKLCQGRLCVPTLEQIGA
                     VELYKTPVSYFKEVNEEYKKRRDVLYNELMKVEGVICKKPTGAFYIVAKLPVENAEDF
                     TIWMLKEFNKDNETVMVCPAEGFYATPGLGRDEIRLAYILNEKDLHRAATLLKEGLEQ
                     YVALQK"
     gene            50838..51788
                     /gene="galT"
                     /locus_tag="ACGI5H_001202"
     CDS             50838..51788
                     /gene="galT"
                     /locus_tag="ACGI5H_001202"
                     /EC_number="2.7.7.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438360.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008108 - UDP-glucose:hexose-1-phosphate
                     uridylyltransferase activity [Evidence IEA];
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA];
                     GO_process: GO:0006012 - galactose metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="galactose-1-phosphate uridylyltransferase"
                     /protein_id="HFG9696915.1"
                     /translation="MKELRIDPITNDVVIFATDRLKRPLDTADIPNEDEETNEYDEEC
                     PFCKGNEAHATDALFEIDSEEGWLVKSVYNKFPIIDDMARDVYGVHEVMIESDKHNRS
                     FYNMSQKEFEDVFFMYRNRFRDLSKDDKVEYVSIFKNFLRKAGASLMHPHAQILSMSF
                     IPPEITNELLVSKEYYDSNKSSLYDDLIENEISLDRRVVYNGEAFLVLIPYATKYSGE
                     VRIIFKDKIEFGELNDNNIQELSTIFEKLFKKLYNINGYMPFNLCIHTHPTKIETKSY
                     FNVHMHIIPRKYNFGGFELGTNMYVSSMSPEDLTKKLKID"
     gene            51949..52701
                     /locus_tag="ACGI5H_001203"
     CDS             51949..52701
                     /locus_tag="ACGI5H_001203"
                     /EC_number="3.1.11.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428204.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004518 - nuclease activity [Evidence
                     IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="exodeoxyribonuclease III"
                     /protein_id="HFG9696916.1"
                     /translation="MKFISWNVNGIRACVGKGFLDFFKEVDADIFCLQETKLQEGQIE
                     LDLPGYFQYWNYAERKGYSGTAIFTKKEPLKVMYGINIEEHDKEGRVITLEFEDFYFV
                     TVYTPNSQSELKRLEYRTRWEDDFIDYLTKLDNHKPVIVCGDMNVAHKEIDLKNPKNN
                     MKNAGFTKEEREKFSKLLDSGFIDTYRYFNPDKEGVYSWWSYRFNARKNNAGWRIDYF
                     CASKKLEDRLVSADIHTEILGSDHCPVELEIK"
     gene            complement(52793..53569)
                     /locus_tag="ACGI5H_001204"
     CDS             complement(52793..53569)
                     /locus_tag="ACGI5H_001204"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889114.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004527 - exonuclease activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="exonuclease domain-containing protein"
                     /protein_id="HFG9696917.1"
                     /translation="MEYIIFDLEFNQGFDKKLNKTVSNEKCPFEIIQIGAIKLDSKFN
                     IIDTFNSYVKPTIYKDIHPFISRMTNIKSSDFNDSPTFPEVYNNFIKFISSQDPILCV
                     WGAGDLKELYRNINYHKLPSNSLPKSYINIQQHASKYFNNPAGKSIGLQNAISILELD
                     EKMSYHNALNDAYYTAKVFIKIYNPSIVPDIYLYTSIKPKTIRYSNKKRVDYDKLFDE
                     FRKILNRELTKDEKKIINLAYNMWKTNQFTLENVKQRKNK"
BASE COUNT        21609 a         5774 c         9523 g        16750 t
ORIGIN      
        1 attttatgcc tagaagttaa aattattata atgtaaaata attttgatta taagctattt
       61 aattgttata ataatattaa aaatttaatt taggagatgt acattaatgt taagtatgaa
      121 tataggagaa atagtagcaa gtttagttgg tatagctatg gcaatatcaa tacatgagtt
      181 tggccatgct tattcagctc acttattggg agatgataca gctaaagctt atggtagaat
      241 gacattaaat cctgtaagac atgttgaccc aataggtctt ttggctatgt ttatccttaa
      301 gatagggtgg gcaaagccag taccagtaaa tccaaataac tttaaaaact ataagatagg
      361 aaacctgata gtttcacttg caggcgtttt ttgtaatgtt ttgactgcta tactgtgtgt
      421 aattatcaat aagtatgtgc atatgtatgc tataaataca atagctgaat atgtgttttt
      481 atatagtatt ggatttgcag cttttaactt acttccgata cctccacttg atggatgggg
      541 agttatatct acatttgtac catataaatg gaatgaatat ttgtataaat ttgaaagcat
      601 gagttatata attttattaa ttgctttatt tactggtatg tatagaataa tattaacacc
      661 aatatatgca gtgttgctaa aaatagtata tttatttgtt taatataata aacagattaa
      721 agagggattg atatgaagta taatatacaa ttacaagtct atgagggacc attagattta
      781 ctttatgatt taataacaaa gcataaaata gatataaagg atatatccat aatagatata
      841 actaagcagt atctaaatta tttgaaaatg ctagataaaa tggatttaga gataactagt
      901 gaatttataa ctatggcatc aaaactttta gagataaagt ctaaatatct gctttataag
      961 caaaaagatg aagaagaaga cccaagaata gaacttatgg aaaagttaga agaatataga
     1021 aagtttaagg tagcatcaca agatataaaa gaaaatataa cttatgttaa tgagagattt
     1081 tatagaaata aagaagagat aattattgat gacaatgtgg atttagaaga tatatcaata
     1141 gaagcaataa aaaatatact tccatacata tttaaagtta aaacatcaca gatagaaaat
     1201 gctaatgatg agaaactaga taaaatagta aggaagaaaa taatatctgt agaagaaaaa
     1261 atattatata taagagatat tataaaagag aagattgaag ttacttttac aaatattata
     1321 aaatcatatg aaaatgatga aataatagct acttttttat ctatattaga gcttataaaa
     1381 gaaaaagaaa tagtcgtagt acaagatata ttttttgatg atattctaat aagaaaaagt
     1441 tcggagtgtt aaaatgaaaa gagaagatat aaagtatatt atagaatctg ttatgtttgc
     1501 atatggtgaa ccaataagta taaaagaatt aaactatata ataaataaag aactttcatc
     1561 aaaagaaata gagattatgt taaatttact tattgaggag tacagagaac aaaatagagg
     1621 tattcaaata atcaagttag agaataagta ccaaatgtgt acaaataaag actatgcaga
     1681 atatataaag aagattattg aaccaaagaa aaagaaaagt ttgagccaag ctacattaga
     1741 aactcttact ataattgcct acaaacaacc aataacaaag gtagaaatag aggatataag
     1801 aggagtaaaa tgtgataagg tattacaaac tttgtttgaa aatgaactta taagagaagc
     1861 tggtagattg aataagatag ggaaaccaat aatttataaa acaacagatg aatttttaaa
     1921 gttgttgaat atagaaagtc ttgaagaatt gccacctata gaaaattatc aagaagtggc
     1981 aacaaatgaa taaaaatata aaatcacaat aatttagtat gtaattttaa attttaaaag
     2041 atttaaaatg ctctaagttg ttgtgttttt ttgtataaat ataaaattat aattctctta
     2101 aaataaatat ggataattaa gtataaatag taattttttg atgataatat aaacatggag
     2161 cttaatgaat tatttaattt taagtattta ataatagctg taatttttat tataagtgta
     2221 actatgttga ttttaatatc tcatataaac atcttaataa tagctgatat aaaaaacaaa
     2281 gatatttgtt taaagcttaa tataaaatac atgtttaatt taataaatat aaatagacaa
     2341 ctttatccag ctgaaaatag taaaaataat gataaaaaag aggggatgaa gaataatata
     2401 gattcaagta tattattagc tgatgacctt ttgagcattt atagattatt aaaaaagata
     2461 aaaatacatg aactttattc aaatattaat tttggaactg gaaatattgg cttaacatct
     2521 tctgtatatg tattgataaa tactttgtat ggaaatttat ttaatatgat tgatgcagaa
     2581 aaaatgtatt taaatgtaaa tccagatttc acaaaagatt atgttttagg aaatataagg
     2641 atacatataa ggccaagaat aaaagcttta tttaatatta taataatgat taataaaatt
     2701 atgaataaaa ataaaggaaa taaggaaggt gatagtaatg agagcaacag gttcgataca
     2761 gagtcttatg gaaacaactc ttgaaacaat taaaggttct atagatgcaa atactattat
     2821 aggagaccct ataaaaacag atactacagt ggttgtacct atatcaaagg ttacaattgg
     2881 ctttggtata ggaggaggag aatactcaaa aggatatgat gataaagata gggaaattga
     2941 attaaaaaat gaaaaatcag atacgaattt tgctggaggt agcgcagggg ctatatctgt
     3001 acaaccagta gcatttgtag tagttgaaag tggagagact agaataatga gtttagatag
     3061 taatatcaat ctagtggata atatattatc tataactcct agagtattgg agaaaattca
     3121 aaatatatca caaagtaata agaatcaaga taaaaacaat atgtaagaat aaaatatttt
     3181 taaatatgta tatagtttta agtaaagtag tggggttaat ataaatccca ctattttgtt
     3241 gtgtacttta aacatttata tctaataaga ttttagttta aaacaattta aatagataat
     3301 aaagttgata tatagtataa ttataaaaag aaaagaagta ttatattata gatatataaa
     3361 cgcatttgag atataagagg gagttataaa tcattagttt tgaggtgaat gttatgagcg
     3421 ataaagaatt atctattttg ttgttagaaa gtatgaataa ttttcataat ttaataaaga
     3481 ttattaataa cgaaagatat aaaaaagata aggttcttac agaaagacag ttctttgcct
     3541 tagtaaaaat aagaaaacat gataaaatag agcttaaaaa tctaagtaga gatttgcatg
     3601 tatctacttc tagtctgtgt atactactta ataaattggt tgagcaagag tatgtatata
     3661 gggaagaaga tagtagagat agacgaaata ctttttatgg aataactaaa aatggagaaa
     3721 agatattgga taatgaaata ctaaagtttg tatctataat aagtgataaa atggattgcc
     3781 tagatataaa taataaagat aaattattta cttctttgga agagtctaaa aatataatag
     3841 aacaattatt ttgaaaagga gaatttatta tgaatataaa gtattctaaa gaaatattaa
     3901 aaagtttaga aaatgctata acagtagtag ctctatttga gggagaagat gtttctacga
     3961 catttgataa aataaatatg ataagcagaa attttaattc taaagaaaat agtatagata
     4021 ctgtaacatt ggttgaaaat aacaatttgg taaatgtttg tcttgttggt tttggtaaga
     4081 gagagttatt gaatagagaa aaaattagaa tcataggtgg gaatttgtgt aaaaaattaa
     4141 aaaatatatt gaaaaatgaa gcatataaga gtagtgatgt taatgtactg aatcttaatt
     4201 taaatagtga tgaaataggt tgttttgtag aagggatatt acttggaaat tataagtttg
     4261 ataaatataa gacaaaaagt aaggattttg aaagaaaaga agttgatact ataactatat
     4321 ttactgaaaa agaagttgag tgtcaaatag aaaaggctaa aatattagct aattcaacta
     4381 taatagctag aaatctagtt aatgaaccat caaacgtaat atatccaaaa acattagcag
     4441 tagaaacagt taaacttggt gcagagtttg ggtttaatgt tgatgtttat gaagaagaaa
     4501 aaataaaggc attgggaatg gatgcttttt tcgctgtttc aagaggttca attaataaac
     4561 caagattcat agtaatgaga tactttggag ataaagaaag tacagatata ttaggtctag
     4621 taggtaaagg attgacttat gatactggtg gatattcttt aaaatcaaat gcttctatgc
     4681 tagatatgaa gacagatatg gctggtgctg cgagtgttat aggtgctatg tgtgctatat
     4741 ctcaaagtaa attaaagaaa aatgttatag cagtagtggc agcatgtgag aatgctttat
     4801 caggaggttc atacaaacct ggagatataa ttagttctat ggcaaagaaa actattgaag
     4861 ttttaaatac ggatgcagaa ggtagactta cattagctga tgcaatatac tacattataa
     4921 acaatgaaaa agtaacaaag gtggttgatg tagctacatt aactggtgct gctttaatat
     4981 tgttaggtaa tgtcgcaact cctatagtaa caaataatga tgatttttat tgtgaattag
     5041 aaaaagctgc cactttatca ggggaaaggg tatggaagat gccaatttat gatgaattta
     5101 aagatatgat aaaaggagaa gaagcagacc ttaaaaacac tggtggtaaa aatgctggat
     5161 gtataacagc aggagctttt attggtgaat ttgttgggaa tactccttgg atacatatgg
     5221 atatagcggg gacaagtaca tcatcaaaat caattggata caaagcaaag ggggctacag
     5281 gagaacctgt tagaacattg tactatttgg cagaaatcta aaaaacaatt ataaaatata
     5341 atttataaag ccacgtggat atttttgtaa tttaagatta tctatgtggc tttatttttt
     5401 atttaaataa attatttact ctttttcttt ttttcaagta taaaagtatc tctattaaat
     5461 aaaagagcag gtatgtacat aatactagta acaaaaataa acgtaaaaat agcagttgtg
     5521 ctatgactta aaaaaccata atagtaccta gagttggtaa atgtgtttag taaaaatatg
     5581 aatgaaaaat aaataaaaca tatagctaag ttatctctaa gtgcatatct gttaactcta
     5641 aattttctaa catcaaccat atatatatct gcataaatta tcaagcactt agagaagata
     5701 aagataaaat atattaagct aggaaattca tagcccaagt ttttagaaaa aatgagttct
     5761 ccaactgaac aaactaaact ccaagaaaaa aatatattaa aaagatgata ctgcttaaaa
     5821 attagtatgg ctatacacag atatatacaa atataattga ttccaattgg taaagagttt
     5881 agagtactat aattacctga agaaataagt aataattgct ctagagccat aattattaca
     5941 agtaatgtac aaattatctt ctcaactgta tagctataag gtaaaatatt tttggttagt
     6001 tttggacaat agtataaaaa taatccaaat ataaagagac ttacaaattg ttcactagaa
     6061 aaaagaaaaa ttttaaacat ataacattct ctcctataat aaatttaata tgtatctata
     6121 taaatatatt cattatatct caatttaata tataaaaaag ataataatag ttagattttt
     6181 tatatgaatt ttaataggta aaatatccta ttgttttgta gatatatcct aattatgtca
     6241 aaaaataaaa aaatttttat ttattagagt ttttggaaat aataataaca gatattataa
     6301 ttaattaaca gtttttgtaa gtatttgaca atagagaggg tgtaacaaat gggaataata
     6361 gagtcagcat caaaattggc tgagatggtt catttattgg ctgttgaaaa ggggataact
     6421 gatatagaag catgggatga agctgtgaaa gaatacagca aaatttatga agaaagaaga
     6481 aatgaataga atgataaaaa atgaaaactt gatgataaaa aataacttta tttaaagaaa
     6541 ttcaattttt atagaagtat taaaaataat ataaataaaa agatggtatt tcaaatgtaa
     6601 gtaaaaaatc attttgggat accatcctta ttatttattt taataatata taagtaataa
     6661 atcttactta tccatatttt ttatgtaacc tcttttttct aactttttta tatgctcctt
     6721 acgtatttca tcaagattaa taccatattg ttcttctagc ttaaacatca tagtaacaca
     6781 tgtctgagct acatccatta gttccttagc agttttcttt ataatatcaa cttcatctaa
     6841 atcattattt tctccactta gatttctgaa tttacctata cattcagcta attcaccttg
     6901 ttcttcaccc attttgataa atgtagattc tagtgttggg tctaaattat taagctctgg
     6961 taaagatata gtttttagtt tcataaaagc tcctttcaag ttattcgtat ttatactaaa
     7021 acatcataac aaaaataata ctaaaaaaaa actttaaatt caacataaaa acttacatat
     7081 ataataaaaa tcgtgaaata aatctatatt tgtcttaata cagcctcata taaaacttct
     7141 ccaataggtt tatttattac aagagaagct gacttatcat agactgtatt tgctttatta
     7201 ataagagcaa tataatcacc tttgtaataa tctataaaac ttgctgctgg gtacacagct
     7261 aatgatgtac ctcctataat caataaatca gcattactta tagcagaaat tgttttagta
     7321 atgacatcac tgtcaagagc ttcctcataa agtactacat ctggttttac tatagaacca
     7381 cagttgtcac agtaaggaat attacctccc agatttaaca tagattctaa gtcaaaaaac
     7441 ttaccacatt tagtacaata atttctatgt acagaaccat gaagttctag cacattttta
     7501 cttccagcca tttgatgaag tccatcaata ttttgagtta tgacagcttt aagcttaccc
     7561 atttcttcga gttttgctaa agctatatga gcattattgg gttttgcatt aggatatatt
     7621 aatttatcct tataaaattc aaaaaattct tctggatatc taacaaaaaa agtatgtgaa
     7681 actaattgtt cagcagtaaa ttgtttattg agtttttggc taaataatcc agtagaactt
     7741 ctaaagtctg gaatattaga ttcagttgaa acacctgctc caccaaaaaa tacaatatta
     7801 ttgtgattag ctattaagtc ttttaagcta tttgcatcca tagttacacc tccaaattat
     7861 tatatataaa ttgtactaca tattaggtcg tttatgtttt attaatttaa ataaatatat
     7921 agtttaataa gttaaataaa gggaatataa ataaaatgta tacagagtat aaatagacaa
     7981 tatttactaa aataacaagt tgtcgtataa ttatattaaa attgttttag tgtataagaa
     8041 gggcggggga agtacgtgaa gaaaaaagca gctttagcaa cattggctat gttaccctta
     8101 ggtgtggtaa atgcacatgc tgatggagat ataggtatag tgactataaa ttatttaaat
     8161 gtaagaaatg aaccaactgc cgaaagtagc atagcctttg ttgctaaaaa agatgataaa
     8221 gttttgatta aagactcttc taatggatgg tataaaataa aagctgaatc tggacaagaa
     8281 ggttgggctt catcaaaata tatagcaaaa tcaaatagtg actctttaag aacgtctaca
     8341 aataaagaaa aacaagttat ttcaaatagt ttaaatatga gaaatggagc aggtacaagt
     8401 tacagagtaa taactgtact aaaaaaaggt caaaaagtag aagtaatatc agagagtaat
     8461 ggatggtcta aaatcaaata tgatggaaga ctaggatatg tatctagctc ttatttagga
     8521 gacgtttcaa actcaactaa taaatcaaaa actaaacaag tgaatacaac ttcactaaat
     8581 gtaaggagtg gaccaaatac aagttatggt ttgttaggca agttgccaaa aggaagtaaa
     8641 gtagaagtaa tatcagaagg taatggatgg tccaaaataa agtataatgg aaaagatgcc
     8701 tatgtatcta gtatgtactt atcggatgta agtcaaagta attcagacaa ttctagtcaa
     8761 agcaatgata aaaagaatac tgataaggtc gtaaatacag cttctttaaa tgtaagaagt
     8821 ggaccaggtt ctacatatag taagttggga aaagtttata aaggaagtaa agtaactgta
     8881 ctatcagaaa gtagtggatg ggctaagatt aattttaaca ataaagaagc atttgtagta
     8941 ggcaattatt tatctacttc agcagatact tcaaataata actcaaatag taactctgat
     9001 aacagttcta atagtaatgg caataattct tcatcatcag gtcaagtaaa tggtatgtca
     9061 ggtataagtg gggctaaaat tgattataaa tctttgagtt atactttaga atctcatata
     9121 agtaaacaag ttgagaaagc agcatcagga ggaaatgtga tagctccaag taataggaaa
     9181 agcactccaa gtcctgaatt tagtactttt tcagctcaaa gaacaagctc atttgtaaat
     9241 gcaagttcaa gtgatataga atattattta aatcctaaaa attttacaaa tactactaaa
     9301 ggtatgatgc agtttttaaa gattaacagt tatagagatg gtatttcaga atcaagtctt
     9361 aactcgtatc ttaatggttt atcttctagt gtatttaaaa accagggagc agcctttata
     9421 aatgctgcca agaagtataa tatagatgtt gtatatctag tatctcatgc tatgtgggaa
     9481 actgcttatg gtaagtctac acttgcccaa ggtcaaacat taacatctta taagggacaa
     9541 cctcttagta agccagttaa agtatacaat ttttttggta taggagcaat agataaaagt
     9601 gctaatgttt caggtgcaga agcagcgtat tccaatggct ggactagtgt agaagctaca
     9661 atagatggct ctgcaaagtg gatatcacaa aattacgtaa atagttctaa gtacaatcag
     9721 aatactatct acaagatgaa gtggaattat gattatacat ggcatcagta tgcaactgat
     9781 gtgaactggg ctaatggaat ttctggaatt atggaaaatt taattggtct ttatggagga
     9841 ggaagtagtt tggtttttga agttcctcaa tacaagtaat acataaataa aaaatataga
     9901 ctatgggtag ttttcatttt atttaaatta tctatagtct ttttgtatat aatttataat
     9961 ctgtaaattt aatgctaaca aaacttttat gttataatat taattctaag taaatataag
    10021 tgagtaatag gtagaaatag ataaaaagtg gtaataatat atataaagat aattttgaga
    10081 aaggaggata tatatggaaa gtattaagga atatttggat aagttagaaa ttaataatag
    10141 tggtcttgga aagcaactta aagaagttta tataaataga gtagtttatt ttaaggaaga
    10201 taagatagtt tatttttatc taacttctaa agatattgtt tctcatgaac ttttagataa
    10261 atttaaagaa gaattgatgt ataaactcga ttattttaaa gatatgagga tgaagataag
    10321 atttactggt cttgaaagaa aatccaataa agatgttata aaaaaatatt ggaataatat
    10381 attgtatata ttaaagtatc tttgtccatc tattgcaggg tggtataaac aagtagaatt
    10441 tctttgttta gaagaagaat taaaaataaa acttccaaaa ggtatatttt atgagcgatt
    10501 aatgaaaaaa aatgtaactt atgtacttaa aaccgtgctt agcgaagagt tgggattaga
    10561 tttaaatata acaatagaaa aagctgttga tgaaaaggta aataaagaaa gactcataag
    10621 aatcaatgat agagaaatgg aagaaaaaat tagggcttta gaaattggaa aagttaataa
    10681 ctgtgaagaa aatgaagagg aaagttatgt cattaagtct gatgtagatg aaaatttaat
    10741 ctatggagat aatgcaaatg ctatgattga aaatatagtt gaattaaatg catcttctgg
    10801 aacagttgca gttgttggag atatatttga tgttgacact aaagaactta aaaacggaaa
    10861 aatacttatg atagcttcaa ttacagatta tactagctca ataagctgta aacttttttt
    10921 aacagataca aataaggatg gagtacttga aaatgttaaa aaaggagcat acttaaaaat
    10981 caagggtgac atagtttatg atacatatca aagagaaatt agtatgatga ttagtgggat
    11041 aagaaaagaa actagaatag agagagaaga taaatcagag gaaaaaagag tagaactcca
    11101 tgcacataca caaatgtctt ctatggatgc tatttgttct gttaaaaagc ttgtagagcg
    11161 tgcagccaaa tggggtcatt ctgctattgc tataacagac catggtgttg tacaaggatt
    11221 tccagatgct atgaatgcag gtaagtcaaa taatataaaa atactttatg gagtagaagg
    11281 gtacttggtt gaagatgatt ctctcattat agaggatgca aatgataaag aactttcgca
    11341 gacatttgtt gtatttgaca tagagacaac tggtttttct aatacaaatg ataaaataac
    11401 tgagattggt gctgtaaaaa tagaaaactt taagattgta gatagattta gtgagttaat
    11461 aaatcctgaa aaagatattt cttataagat acaggaattg acaggaataa ctaatgaatt
    11521 aattaaagac aagccaacca ttgaagaagt tcttcctaag tttatggaat ttgttggaga
    11581 tagtgtatta gtagcacata atgcagagtt tgatactgga tttatatcgc aaaaatgtag
    11641 ggaacaaggc ttgttatata ataacaaaaa agtagataca cttatgttag caagagtaat
    11701 gttgccaaac ttaaaaagac atagattaaa tgtcgttgca aaagaacttg gtattcctct
    11761 tttaaatcac catagagcag tggatgatgc tgaagctaca gcacttatat ttaataagtt
    11821 tttgcagatg cttacagaaa aaggtgcaaa aactctaagt gatgtaaaca atatacttgg
    11881 aaagattgat tacacaaagc ttagcacaaa tcatataacc ttgatagcaa aaaattctat
    11941 aggtataaaa aatttatata aaataatttc agatgcacat gtaaatcatt tttttagagc
    12001 accaagaatc cttagaagtg tattaaatga atataaagaa ggattaataa ttggttcggc
    12061 ttgtgaagct ggggtggttt ttcaagctgt aaagaaaaac gtgtctgatg aggaaatgaa
    12121 aaaaataata gatttatacg attatattga agtaatgcct atagataata atagatttat
    12181 gattgataaa ggagaagtaa aggacgaaga agagttaagg gagttgaata ggaaattaat
    12241 tgatacagcc aaaaaatttg acaaaattcc agtagctact ggggatgttc attttttaga
    12301 caaacatgaa gctgtcttaa gaaaagttct taaatattct caaggtttta aagtagatga
    12361 agaagaaact tatttacatt ttagaacaac agatgaaatg ttggaagagt ttagttatct
    12421 tggagaagaa ttggcatatg aagttgtagt tgaaaatagt aatctgattg ccgatatggt
    12481 tgaagatata aaacctatac cagatgatac ttatcctcca attatagagg gctcagatgt
    12541 ggagttaaga gaaatgtgtt acaaaaaagc caaacgaatc tatggagacc caataccaga
    12601 aatagttcaa aaaagactgg atagagaatt aaattcaata ataagcaatg ggtatgcagt
    12661 tatgtatatt atagctcaaa aactggttgc aaaatctctt tcagatggat atttagttgg
    12721 ttcaagaggc tcagttggct catcttttgc agctactatg agtgatataa cagaagttaa
    12781 tcctcttcca gcacattata tttgtgaaaa cgaagactgt aaatattcat tcttttatga
    12841 aataggtgaa tggggctcag gtgttgattt accagacaag gattgtccaa agtgtggaag
    12901 aaaacttgct aaaaacggtc atgatattcc atttgaggtt ttcttaggtt ttgaaggtga
    12961 taaagaacca gatatagact taaatttctc aggaaattat cagccaacaa ttcataaata
    13021 cacagaagaa ctatttggag aggggtatgt atatagggct gggactatag gtactgtagc
    13081 agaaaaaaca gcttttggat acgcaagaaa atatgtggaa gaaaataata taagtgtacc
    13141 aaatgcagaa gtacttaggc tttcaaatgg atgtactgga gtaaaaagaa cctcaggaca
    13201 acatcctggt ggagttatgg ttataccaga ctataaagat gtatacgatt ttacacctat
    13261 acagtatcca gcaaatgata cttcttgtgg tgttataact actcactttg attatcattc
    13321 aataagtggt agaatactta aacttgatat acttggacac gacggtccta ccattataag
    13381 gatgcttgaa gatatgactg gaataaatat aacagaaatt cctttagatg ataaagagac
    13441 tatgtctcta tttacatcta cagaagcatt aggtgttaca ccagaagaaa taaactgtcc
    13501 tataggttgc cttgctgtac cagagtttgg aactaagttt gtacgacaaa tgttacttga
    13561 cacaaaacct actacatttg cagaacttgt acgtatatct ggtctctctc atgggacaga
    13621 tgtttgggta aataatgcac aagacttagt tagagaagat atagttggat taaaagatgt
    13681 tatatctaca cgagatgaca taatgaacta tttaatattt aaaggattac ctcccaaaat
    13741 gagctttaca ataatggaga gtgtaagaaa aggtaaaggt ttaaaaccag aacacattga
    13801 agaaatgaaa aaaaataatg ttccagaatg gtatataggc tcatgtaaaa agattaagta
    13861 catgttccca aaagcacatg ctgttgctta tgtaatgaca tcatttagaa ttgcatattg
    13921 taaagttcac tatccagaag cattttatgc gacttatttt acgacaaaag ttgaggattt
    13981 tgatgcagat ttaattgtta aaggattaga tgctataaaa tcaaaaataa atgaaattga
    14041 gtcactggga aatgatgcaa ccacaaaaga aaaaggtatg ttgaccgttt tagaagttgc
    14101 tcttgaaatg tatgctagag gaataaaatt attaccagtt gatatatata aatcagatgc
    14161 aactgagttt atagttgtag gagaaaaaac attacttcca ccaatggcag caatacaagg
    14221 tcttggagga aatgcggcta taaacatcca aaatgaaaga aaaaatggtg aatttatatc
    14281 aaaagaagat ttgagaaaga gaacaaaaat atcaaaaacg gtaatagaaa ctcttactaa
    14341 tcatggttca cttgagaata tgagtgagag aaatcaattg tcattgtttt aagttagccc
    14401 aaaaagttgc aaataaaaga attttatgat atcatagtat agaaaatagt atactttgca
    14461 gaaactaaga gtgagacagc tgttctcact cttttatttt aaatatatta ttaaaaagct
    14521 ggtttatttt tattaaatat attttattta agattatata aactggtcat ttacaattga
    14581 ataggaggaa ctttaatgaa aaaaaattta gaagctacaa ttgaggagat tgtaactaaa
    14641 ataacggatg aacatggatt tgaaatggtt gatgttgaat atgtaaaaga agcaggagaa
    14701 tactacttaa gagtatacat agataaagaa gaaggaatat ctttaaatga atgtgaatta
    14761 gttagtagag aattaagtcc aatactagat gaaaaagacc ctataaaaga aaattacttt
    14821 ttagaggtat cttctccagg gcttgataga gcattaaaaa aagacagaga ttttgttaga
    14881 tatcaaggta gagatgtaga tttaaaatta tataaaccat taaatggatg taagcaattt
    14941 gaaggtgaac ttgtaggatt aacagaagat aataatataa aaatcattgc aaatggtaag
    15001 gaaatggaat ttaatagaaa agatgttgct attgtcagat tagcaataaa gttttagtgg
    15061 tatattaaat agggaggata taaaaaatga atcatgaatt tatggaagca ttagatgaat
    15121 tagtagttga cagaggtata gataaagaaa tacttataga tactatagaa caagctcttt
    15181 taactgcata caagaaaaac tttggttcag cacaaaatgt tagagttgaa tttgatagag
    15241 acaagggaga tataaaagta ttttctcaaa gagttgttgt tgatgaatca gatttatatg
    15301 atactttctt agaaatagag ttagcagatg ctagagagat aaaccctaat tatgaattag
    15361 gtgatattat agaacatgaa gttacaccta aaaactttgg aagaattgca gctcaaacag
    15421 caaagcaagt agttgttcaa agaataaggg aagctgagag agaaatagtg tataatgaat
    15481 ttatagaaaa agaaaatgaa atagttacag gagaggttgc tagagcaaat aaaaatgttg
    15541 tttatgtaaa tcttggaaga atagaaggta taatgactca aagtgaacaa ataccatttg
    15601 agaattataa agcaggtcaa aaaataaaat tctatatact tgaagttaaa aagactaaca
    15661 aaggacctca aatagttgta tcaagaagtc atccgggtct agtaaagaga ttgtttgaag
    15721 aagaagttcc tgaaatatat gaaggaatag ttcaaataaa atctgtagca agagaagcag
    15781 ggtcaagaac taaaatggca gtaagatcta tagatgaaaa aatagaccca attggagctt
    15841 gtgttggacc aaaaggactt agagtaaaaa atatagtgga tgaacttggc gatgagaaaa
    15901 tagatataat aaaatatagt gaagacccag cagagtttat atcagcagca cttagcccat
    15961 caaaggttgt tagagtagat atagatgaag atgaaaagtc tgccttagta atcgttccag
    16021 attatcagtt atcgcttgct ataggtaaag aaggtcaaaa tgcaagacta gcagcaaaat
    16081 tgactaactg gaaaatagat attaagagcg aatctcaagc agaacaagaa atgttaaatc
    16141 ttgaaaattc caaagaaata gaagctgagg atgttgaagc tgaatttatc gaccaagaag
    16201 agttagatac ttcagaggat aattttagtg aagaagagta aggagggatg attttgaaaa
    16261 aagtaaaaaa agtgcctcaa agaaaatgca tagcatgtca agatagagac tctaaaaaag
    16321 agcttataag aatagttaaa aataaagaag gaaaaatatt tttagaccca acaggaagag
    16381 ccaatggaag aggagcatat gtatgtaaaa gctctgaatg tctaaaaaaa gctataaaga
    16441 gtaaagcatt aaataaagct tttaaaatag atgttcctga tgaagtctat gataatctac
    16501 ttatggagtt agaagaatat gaaaaataat aaagaaaaag tactttcgtt cttagggctc
    16561 gcaactcgtg cagggaaaat agtgtctggt gatgattcaa ctttgcttga ccttaaaaaa
    16621 ggaaaagtaa atttgatttt aatcgcagaa gatgcatcaa ataatactaa aaaacttttt
    16681 aaagataaat caacttttag aaatattcca tatctatttt tttcaacaaa agaggaaata
    16741 ggatttgcaa taggaaaatc tccaagagca gttgtaggaa taaaagatga aaatttttct
    16801 aaaaagataa ttgaactaat agaaatttaa aataaaatag ggggtgatct tgtgtcaaaa
    16861 acaagagtat accaaatagc agaagaatta aatatatcaa atgaagagct tataaataag
    16921 ttagctgaat tagatataaa tgtaactgac aaagattcag tattagaagg tgaagagtta
    16981 gaattagcac ttgaaatgtt aggtgaagat ttatctcaag aaaatggaaa tgttatagaa
    17041 atagatggaa agttgacagt acaagtatta gcaacgaaat tagataaatc tccatcagaa
    17101 ataattatga agcttatgaa aatgggaact atggcaacaa taaatcaaga gataagtttt
    17161 gagattgctg ctttggctgc caaagactat ggatttgaat taacagtagc tgaaagtgat
    17221 gatacagaag ctttagaaat agaagcttta atggaaattg aagaagataa agaagaggat
    17281 ttaaaaccta gaccaccagt tgttacagtt atgggacatg ttgaccatgg taagacatct
    17341 ttactagatg caataagaaa aactgatgtg atttcaggtg aagctggagg aataactcag
    17401 catataggtg cttcagaagt taaaatcaat ggacacaaaa tagtattttt agatactcca
    17461 ggacatgagg ctttcacatc aatgagagca agaggagcac aagttacaga tatagcaata
    17521 ttagtagttg cagcagatga tggtataatg cctcaaacag ttgaagctat aaaccatgct
    17581 aaagcagcag gtgtaccttt aatagttgct attaataaaa tagataaacc aggtgcaaac
    17641 ccagataagg ttaaacagga attagcagac caaggattat tagttgaaga ctggggtgga
    17701 gaagtaatag cagttccagt atcagctaag aaaaaagaag gaatagatac acttttagaa
    17761 atggtattat tggttgctga aatggaagag ttaagagcta atccaaataa aagagcagta
    17821 ggaactgtta tagaagctga gcttgataaa ggaagagggc cagttgcaac agtacttgtt
    17881 caaggtggta ctttaacagt aggtgaccca atcgttgcag gtgttgcatg tggtaaagtt
    17941 agagcaatga taaatgcaaa aggtaagaga gtaaaaacag caggaccatc tacagcagtc
    18001 gagatattag gtctatcaga agttccacaa ggaggagacc aatttgtcga agttccaact
    18061 gataagattg ctagaagtgt agcagcaaga agacaacaaa tagttagaga tgaaatgtta
    18121 aaatcaactc aaagattatc actagatgct ctatttagtc aaatgagtga aggttctata
    18181 aaagacctta atatagttat aaaagcagat gtacaaggtt cagtacaggc agttaaacaa
    18241 tctttagaaa aattatcaaa tgaagaagtt caagttaaag taatacatgg tggtgttgga
    18301 gctgtaacag aatcagacat attacttgca gcagcttcta acgcaataat aataggattc
    18361 aatgtaagac cagttccagg tgcagaatct ctaggagaaa aagaaaatgt tgatataaga
    18421 acatatacta taatatacaa ggcaatagaa gatatacaag cggctatgac tggtatgtta
    18481 gaccctgaat atgttgatga agaaacagga aaagctgaaa taagagaaat atataaaata
    18541 tctggtgttg gaacagtagc tggatgttat gtgactaatg gtaagatatt tagaaattgt
    18601 aaagtaagat tagttagaga tagcataata atacatgaag gtgagcttgc agcacttaag
    18661 agatttaaag atgatgtaaa agaagttaat tctggatacg aatgtggtat gagttttgta
    18721 aattataacg acataaaaga aggcgatata gtagaagctt atataactaa agaagtagaa
    18781 agaaaattat aaattcgtat caaagaaaat cagttagtaa agaaggtcga tggtatggca
    18841 tcatataata gaacaagaag gatagcagaa gaaataagaa aagtcgtaag cactatgctt
    18901 ataaatggag taaaagaccc tagaataaca tctatggtga gtgtaactga tgtagaagtt
    18961 acaaatgacc taagatatgc ttatgtatat gtaagcattc taggtggaga tgaagaatcc
    19021 acactaacag gtcttaaaag tgctggagga tatataagaa gagaagtagg aaaaaatata
    19081 aaacttagat atattcctga aatagtattt aaacttgatg attcaataga aaaaggaatg
    19141 tatatggata gccttataaa aagagttaat gaaaaaaatg ctcaacaaaa tgaggatgaa
    19201 aattatgatg aataatatgg atagtattat aaactatatt tatgagggtg actattttat
    19261 agttacctct catatcagtc cagatggaga caatattggt tctacacttt caatgtatta
    19321 tacattgaag aatttaggaa aaaatgtata ttatgtactt gatgatgaag ctccattaaa
    19381 tttaaggttt ttggttgaag atgtaaaaat ctataagtct aatgaattta atatgaagaa
    19441 ctattctcta attgcacttg attgtgggga taagatgaga atatgtgtga gtgatgaaat
    19501 caaaaataat gcatcaaaat taatctgtat tgaccatcat gctagtaatg attcatatgg
    19561 agatttaaat tatgtagata ttgatgcatc ttctacatgt gaattagttt ataatttatt
    19621 agttagattt cagcaaataa aagatattaa tattataaat gaagatatag caacatgttt
    19681 atatacaggt cttgtaactg atactggaaa cttttcgtat tcaaatgtac atgcaagtag
    19741 ctttgaaatg gcaaaaaatt tacttgtttt aggtgcacaa aaaaatacta taatacaaaa
    19801 tatatatcaa agcaattctt ctggttatta caaattatta ggagaagctc taaagggttt
    19861 ggagatattt gattcaaagg tatctagtat agttttaact caagacatga tgaatagaaa
    19921 taatattagc tttaatgatg ttgatggaat aacaacatat acaagagaca taaaaggtat
    19981 agaagttgga attttattta aagagaaaaa acaaaatgaa attaaagtga gttttaggtc
    20041 aaaaaattat gttgatgtaa gtgaaatagc caagttattt ggtggtggtg gtcatgtaag
    20101 ggctgctgga tgtactatta gagatagtat tgataatgca aagaaaatgg tactagaggc
    20161 agtgttaaaa tcaatttaag gtgacagtaa aatgaataag attataagta tattgaaacc
    20221 cacaggtatg acatctcatg atgttgtaag tagagtgaga aagattttaa atataaaaaa
    20281 agttggtcat acaggtactc ttgacccaga tgcttcaggt gttttaccaa tctgtatagg
    20341 gaaagctaca aaagtatgtg aagttatttt aaacaaagat aaatcgtata tatgtgagct
    20401 tactttaggt ataagtacag atacttatga tgcttcaggt gaaattttaa aaaaagttga
    20461 tgattttaaa tttagtaatg aagacataga aagagctttt gacacacaaa gaggagagat
    20521 aaatcaactt cctccaattt attcagcttt aaaggtaaat ggaaagagaa tgtgtgattt
    20581 agtaagaagt ggtagacaat ctgaaattac tttaaaaaca agaagagtaa atataaaaga
    20641 cataaaaata ctaagtataa aaggtaataa agtaatgttt tatgttgagt gttctaaagg
    20701 gacttatgtg agaagtattt gccatgatat aggagaatat ctaggttgtg gagctcatat
    20761 gtcgtttttg aatagaacat cttctggtaa atttgactta gataattcaa taacattaga
    20821 agaattagaa ttattttatg aaaataaaac tttagacaaa tacttatatg atatagatta
    20881 tgtccttgat tcgtttaatt atgttgtatt aaaccctaat gctataaaat attatagtaa
    20941 tggtggctca atagatgata aaaggttttt aaagaataat ttcgataaag atgatgaatt
    21001 tgtaagagta tacagtacag ataatttctt aggattagga aagttatcaa aacacaataa
    21061 tacaataagt gttaaaagtg ataagatgtt catataacca atgtatttaa aaaaacaaca
    21121 aaagagatag tactataata acttctatag tctatctctt ttacttatgc tataatagtt
    21181 tgtgaataag ttaagagtaa attatatttt agcggggaac atttattatg gtgattataa
    21241 aatctataaa agaaatagca aacataaaag aaagtgtcat taccatagga aattttgatg
    21301 gtgtacacaa aggacatcaa gttcttatag gaaaaacagt tgaacatgca aaaaaagaaa
    21361 atatacagag tattgtattt acatttgcaa atcatcctgt aaattacttt agaccaaact
    21421 caacaaaaaa tattataagc aatgatgata aaataaaatt attagaagat ttgggaatag
    21481 atatagttgt aatcatacca tttgatgagt atatgactaa aatacctgca aaggatttcg
    21541 tagatgagat actagtaaaa aaattaaaag ctaaaaagat agtaattgga catgacttta
    21601 catttgcaag ggcaaaagaa ggcaatgtta atctattaaa aagcttagaa catgaatttg
    21661 gttttgaggt agaagtaata aaacccatca aaatcaatga tgtaagagtg agtagtactt
    21721 atattagaag tttagtatcc cagggtgata tggctaatgt caaggaatat ttgggtagaa
    21781 attacaagtt agaaggttgt gttatacatt ctaaacacct tggaagaact ataggattcc
    21841 caacggcaaa tattgacctt aagaataata tgctcgttcc aaagagaggt atttatgctt
    21901 ctattgtaca tattggagat gagacttatt ttggtgctac aaatgtaggc tataacccaa
    21961 cagttaatgg aaaaactttg tctattgaaa caaatatttt agagtttgat agagatattt
    22021 atggggaaaa tataattgtt gaatttttgg aaagaataag agatgaaaga aagtttaatt
    22081 caatagatga cttaaaaaat caattgtata atgatacaaa ttatgtgtat gaaaactatg
    22141 tttgcaaaaa caagtaatgt atgataaaat gattaaggaa aataaccatt actcggcatt
    22201 tgaatactcc aatcaatgct tagtaatagg cgtttctaaa aaaatacgga ggtaatctaa
    22261 atgataaaca aatcagaaat aataaaagaa tatggaagag ctgaagggga tactggttct
    22321 ccagaagtac aaatagcttt attaacagct agaataaacg agttaaatgg acatttaaaa
    22381 actcataaga aagaccacca ttcaagaaga ggactattaa aaatggttgg tagaagaaga
    22441 aacttattag cttacttaaa ggaaaaagat cttgaaggat atagagcatt aatagctaaa
    22501 ttaggattaa gaaagtaatt tcattcttta taaaaaagca ggtatagtgt atacctgctt
    22561 ttttatagtt aattcattat aaagtaaaat agttaataat aaaagtagtt tatatgttat
    22621 aaaaaattat aaaatgaata atattgggta agaatattaa aatagtatac aaatacataa
    22681 tcaatttaaa aggaaagaca ggataaatat agaaatttta taacaggata attagttgga
    22741 ataaggagga tattattttg aaaataaagt tagtatgcga tagtttgtgc gatattccag
    22801 atgaaatatc ggaaaaagat tatatagaga tagttccact tacagttatt tttaatgata
    22861 gggaatatat agaaggagta gatataaaga aagaagagtt ttataaaaaa gtaaaagaaa
    22921 tcaagcaaat acctaaaact tcacaagcta catatatgga gtttaaagaa gtgtttgata
    22981 agttcataac agaaggttat catataatct gtatgacagg ggctgcaaac gcatcaggaa
    23041 cttttcaaag tgctatgata gctaaaaatg atgtaaatga aaatgaaaaa atacatatat
    23101 ttgatactag aaatttatct ctaggtagtg gacaatatgt tataaaggca tgtgaacttc
    23161 ttgaagaagg actgggattt gaagaaatta tagatgaatt agaaaatact cgcagtagtg
    23221 taagattgct ttttgcacca tatacacttg attttttaaa gcagagtgga agagttccag
    23281 ttgcaactgc tttgatagga aatatgttaa atataaagcc tatatttttc tttgataatg
    23341 gggaagctaa gttggtaaat aaggttagag gaataaagaa tatagcaagt aaattggtcg
    23401 atataatttt agaaatgaat gaagggtctt tagaaggaaa aatcgtcaca ataggttgtg
    23461 gagataattt acacgattgt gaaatattaa aagatgaagt aaataaaaga ataaaagcaa
    23521 gaagagtatt atttactcga ggaggagttt ctatttgctc tcatacagga ccagatatat
    23581 tggctataag ttgttctaat tagtagtaat ataaggtttt tgcatatata tgtgaagata
    23641 attttatatt gttaatttat agtatttttg ataatatagt aaatagagtg atatacgtgt
    23701 tttttaataa gaggaggaca agcattaatg tttgaacata aaatatttaa aatggatttt
    23761 gcaggaagag aactttctgt agaaatagga aagatttgtg aaatggctag tggtagttgt
    23821 atagttcgat acagtgatag tatggtaatg gtaaatacaa ctaaatcagc caaacctaga
    23881 gacggaatag acttttttcc tttaagtgtg gattatgaag aaaaattata ctctgtaggt
    23941 aagatacctg gaggtttttt aaagagagaa ggcaagcctt cagagaaagc tatacttaca
    24001 tcaagattga tagatagacc aataagacct ttattcccaa aaggatttag aaatgatgtt
    24061 caggtagttg caacagttct atcagtagac caagattgta caccagatat agtagcaatg
    24121 ataggttctt caatagccct ttctatatca gacataccat ttaatggacc aacaggttca
    24181 gtatgtgttg gccttgtaga tggtgcattt gttgtaaatc caaacgcaga gcaaagagaa
    24241 aaaagttcaa tgcatctagt tgtttcaggt acaaaggaag caataatgat ggttgaagcc
    24301 ggagctgatg aagttccaga tgaggtaatg cttgatgcta ttttatttgc tcaccaagaa
    24361 ataaaaaaaa tagttgagtt tatagaaggt atagttgcag aagttggaaa agaaaaaatg
    24421 cctgttgaat tataccatgc aggagaagaa ataactcaat tggttcgcga atttgcaact
    24481 gataagatga aaaaagcagt tcagactttt gaaaagttag agagaatgga aaatatggat
    24541 agagttaaag aagaaacttt agctcacttt gaagaaactt tagaagattt tgaagatttt
    24601 gttggagata tagaagaagt attacaagat ataataaaag aagaagtaag aaaacttata
    24661 gtacatgaaa atgtaagacc agataataga aaacttgaag aaataagacc tatatggtgt
    24721 gaaactggca tgatacctag agctcatggt tcagccatat ttactagagg acaaactcaa
    24781 gtacttaatg ttgctacttt aggtgcttta ggagatgttc aaaaactaga tgggttagat
    24841 gaagaagaaa acaagagata tatgcatcat tataatttcc ctgcatatag tgttggagaa
    24901 gctagaccat caagaggtcc aggaagaaga gaaataggac atggtgcttt agcagaaaga
    24961 gctttattac cagtaatacc atctcaagaa gaatttcctt atgctattag attagtttct
    25021 gaagtattaa gttcaaatgg ttctacatct caagcaagtg tatgtggttc aacattatct
    25081 ttacttgatg caggtgtacc tataaaagat atggttgcag gtatagcaat gggacttata
    25141 aagcatgatg gtaaggttgc agtgctttca gatatacaag gtatggaaga ccatttaggc
    25201 gatatggact ttaaagtagc tggaacagag tatggtataa cagcaataca aatggatata
    25261 aaaattgatg gtatagataa agaaattcta caacgtgctt taaaacaagc taaagagggt
    25321 agaatccata tactaggaga gatgagaaaa actatatctc agccaaaacc agaactttca
    25381 ccatatgcac ctaagattgt taaaatgcaa ataaatcctg acaagataaa agatgtaata
    25441 ggacctggtg gaaagataat aactaagata atagacgaaa ctggagttaa gatagatatt
    25501 gaacaaactg gggaagtatt tatatcaggt attgagattg atatgattaa gaaagctcaa
    25561 gaacttataa ataatatagt agttgaacca gaagtaggaa aaacttataa aggtaaggta
    25621 agtagaataa tgaactttgg agcatttgtt gagatacttc caggaaaaga aggattactt
    25681 catatatctc atatagctca tgaaagagtt gccaaagttg aagatgtatt gaatataggg
    25741 gatgaagttg aagttaaagt tacagagatt gatgaaaaag gaagagttaa tttatcaaga
    25801 aaagttcttt taccaaaacc agaacataaa aataaataac ttattatata attaaaagca
    25861 aagtcttagg attttgcttt tttaaataca aaaaagtaga taattttaaa atgatagtta
    25921 tggatggctt atagttcttt ttctgtcagt ctttactctt ataaagaagc tatttaaaag
    25981 ctgattaata gaaagcttta ttgatatata tagaatcact taagttatat ttagtgcata
    26041 aacagagctt atttttaata gtattaaata agaaacaatt tgtacataat tagggggagt
    26101 tttaatgata atgatggtac ttaataagag taagctcaaa aaaatcataa tactaatttt
    26161 agtagtgtta ttagtattat caggaggggt aatggtatta aagttattta acaacaagcc
    26221 agtatttaat ttatttaatg gtgtagattt accatatgaa agaggtacaa aggataaaag
    26281 tggatatgtt gcattaacct gtaatataga ccttggatgg gaaacagagt acgtagaatc
    26341 cattttagaa acacttaaaa aagaaaatgt aaagattaca tttaatgtaa ctggaaaatg
    26401 ggcagaaaag aataaggatg aattattaaa gataaaaaaa caaggacatg aaataggtaa
    26461 tcatggatat aaacatttag attattctac attatcatat gaagacaatt atgagcaaat
    26521 agagacctct aaaaagataa ttgaagaaat tataggtgaa aaaactaaat tttttcaagc
    26581 accagcaggt tcctttggtc cagaaacagt aaaggctgct aaagcattag ggtatacttc
    26641 tatcaaatgg gatgccgata ctatagattg gaaatacaaa gaccaaccag aggtaatcat
    26701 tgatagaatg aagaaaaaag acattaaaga tagtagtata atcttaatgc atccaaccaa
    26761 cgcaacgaca aaatgtatag atgatattat agctattgta agagaaaaag gactaaaagc
    26821 aggaaaactt agtgatgtat ttaagtagac aaagtataaa tatttggtta agattgtata
    26881 agttgtagtt gaattaatta aaagactgac ttataatgta atacatataa aaaataaata
    26941 taattaaaac atagtgtttt caataatcca atatgaaaca aagaataaat tgttaggaga
    27001 atgtaatgta taagacaaaa atactggaaa atgggcttac aataattggt gaagaaatac
    27061 catatctaaa gtcaataaca ttaggtattt ggataaatgc aggctctagg atagaagaag
    27121 cacaggtgag tggaacttct cattttatag agcatatgat gtttaaagga accaaaaaca
    27181 gaacatcaaa agagattgct agttcaatag ataatttggg tggtcaaata aatgcattta
    27241 caagtaaaga atgtacatgt tattatgtaa aactaataga tgagcatata gatacaggaa
    27301 ttgatgtatt gagtgatatg atactaaatt ctaaatttga taaaaatgat atagataagg
    27361 aaagacttat aatattggaa gaacttaaga tgtatgaaga ctctccagat gacttatctt
    27421 atgatttatt agtggaaaat atatatgcta atgatggatt aggaatgaat ataattggga
    27481 caaaagaatc tctatacaat ataactagag aatccatgtt agaatactta aataagtatt
    27541 atattccaaa taacgctgtt atttctatag ctggaaactt taactttgat gatatggtgg
    27601 agaaaatcaa atcaaaattt ggacactggg aaaagaaaaa tttgagtata gacataagtg
    27661 aggctaagtt taatccttgc tttatatcaa aaaataaaga tactgaacag gtgaacttag
    27721 ctatgtgcct aaaaggtatt ccttttgaaa atgatgaaga agtctattca atggcagtgg
    27781 taaataatat tttcggtgga agtataagct caaggctttt tcagaaaata agggaagaaa
    27841 aaggtttagt atattcaata tactcatcac agacattata taggaaatgt ggtgaattag
    27901 gtatatttgc aagcatgagt acagaaaatt tacaagatgt atataattta ataaagaaag
    27961 aaattgaaaa tataagagaa aactatctta cagaaaaaga aatatctgaa agcaaggaac
    28021 agttaaaagg aaattatata ttggatttag aaagtactag cagtagaatg atgtctactg
    28081 gtaaatctat gttacttagt aaaaaagtaa aaactacaga tgaaatactt gaatgtataa
    28141 atagtgttaa tattaattca ataaagaagg ttgttgataa ggtattcaat atcgaaaata
    28201 ttggtacatg tatagttgga agagatgtag aaaagattct acacttggat taatattgaa
    28261 aaaagtaaat ctctggaggt ataaaatatg aatttatctg aaatagcagg taaggaaata
    28321 gttaacttgg tcacaggaga aagattgggg gtcattggag aatgtgacct tatactagat
    28381 gaaactacag gcggtatatt agcgcttcta attccaaaag aaaaaggatt ttttgccaga
    28441 agaaaagata agtcattttt agaagtacca tggagaaatg taaaaaaaat aggtaatgac
    28501 atgataatta tagaatatga gggatatatt taggaggaaa aaatgagtat tttagtgcaa
    28561 aagtttggtg ggacatcagt agaatcatat gaaaaaatga atgaagtatg taagatagta
    28621 aaagcataca aaaaaaatga tgaagaatta caattagtat tagtagtttc agcaatggga
    28681 agaaaaggag ctccatatgc tacagataca cttataaatt tgtgtagtgc agtaaatgat
    28741 gagccaagta aaagagaact tgatttaata atgtcttgtg gagaaataat atcaggaaca
    28801 attcttgcta atttattgaa tgcacagggg atagattctg ttttctttac tggtcagcaa
    28861 gcaggtataa ttacaagtga tgaatattct aatgcaaaga taaagtatat aaatcctaaa
    28921 aaggtaaaaa gagctttaga tgatggtaag gttgtagtta tagctgggtt ccagggtgta
    28981 acagatgatg gagaaataac tactcttgga agaggcggaa gcgatacatc agcagttgct
    29041 attggtaaag ctttagaatg tgaaacagtt gaaatttaca ctgatgtgga tggtataatg
    29101 actgcagacc ctagagtaga accaaacgct aaagtattga gttttataga ctatgaggaa
    29161 gtattccaaa tggctgacaa aggtgcaaaa gtaatacatc caagagcagt acagttggct
    29221 aaaagtggaa atataacttt agccataaag aatacaatga atccaacttt tgaaggtaca
    29281 aaaataggtt ctttatgtag acacttagaa gacaatatag aatatgaaca agaaagagat
    29341 tttaaggttg ctgttgcaaa taaagatagc gtagcacaag ttaagattaa gtcagcagaa
    29401 gaagtgttta cagaagtatt aaatgagata gaaaagaaac ttataactat agatatgata
    29461 aatttcttta tatcagaaaa agcatttgtt gtagaagatg ctgatataaa atcattaaag
    29521 gaaatactag ataaatttga attagattat gaagtaaata gagactgtgc taaggtaaca
    29581 ttgatatgtt caagaattgc tgatgaaatg tctggtatca tgtcaaaggt agttagagga
    29641 ttatcaaaag caggggtatc ccttttacaa acatcagact caaatatgac tatatcttgt
    29701 ttagttagtg aagaagatat gcatacagca gtacatgcta tacatcaaca attttattta
    29761 aaataaactg tataatacaa ttatttttta atcaaattta agaatttcat atatatctta
    29821 atatatttga tttatttggt aaaactaaat taaatataat tttgatagga gtttttttat
    29881 gaaagattat agagaagata atgaaagatt tgataaagat aattgtagtg aagaatctag
    29941 ttgcgaagag agagaatgta taaagcaatt tggtaccaat gaaatgccac ctcaacctcc
    30001 taaagatatt caatgtataa ctataattgg agaaattgag ggacatttta taggaaatcc
    30061 tcaaaaaaaa gctacaaagt acgagcatat aattccaatg ctatactcaa ttgaggaaag
    30121 taatgatgtt aaaggagtgt tagttgtttt aaacactgtt ggaggagata ttgaagcagg
    30181 tttagctatt gcagaacttt taaacagtac atctaaaaaa gtagttactc ttgttctagg
    30241 aggaagtcat agtataggtg ttcctcttgc tacagcagga gattactcat ttatagcacc
    30301 aacagcaacc atgattatac atccagtgcg aactactggt cttgtgattg ggataaatga
    30361 gacttttgag tattttaaaa agatgcaaga tagaataatt caatttataa taagaacatc
    30421 aaatatcaaa aaagatgtac ttgaaaaact tatgcatgaa aaagatgaac ttgtaagtga
    30481 tgttggtagt gtattaatag gaaaagaagc tgtggattat ggtcttatag atgaagttgg
    30541 aggactaaaa gaagcactta aaaaattaag agagcttata aaagaatctg aggaagaaaa
    30601 aaataatgat taaaatttgt ttaaataata aaatttatga tataatgatg taataaagta
    30661 ggagtgttag tgttaaggca ttagcacttt ttgctgtgaa ggggtaaaac ttgctaaaaa
    30721 taaggagtga tattaatggc cacgaaaaag aagaaaaaaa agaaggtaaa taccttaagt
    30781 tttaatgcag aatatcataa tttaataaca atatttatag gtgtattttt attatatagt
    30841 ttaaattcta attctatggg atggatacct gtgttaatgc aaaatctttt taagggacta
    30901 tttggagggc tttcaatagc aataccattt atagtaatta taacaggact tttaggattt
    30961 tttgatggaa atgaatatat atataggcta agaaagacta aactatacta cataattatt
    31021 ttatttatat ttgtatttta tggattatta aatgcaggaa ctcttcctgt agatagccca
    31081 ctaaaaggta acatgtttga tgatgttatg aaattgggtg taagtggaca aggtagtggt
    31141 ttgatagcaa caactattgc gtattatatg agtaaaatat ttggtatagc aggtggatgg
    31201 ttaataagta tcttcgcact tatactttct gtaatgttta tatttaatat ttctataaaa
    31261 gatttggtgt caaatgcaaa atcaaaatct aaagcatcta aagacagcaa tttaacgttt
    31321 aaagataaaa ttgcaaatat gaaaaaatct gcaatagata tgatgactga tgaagtagat
    31381 gatactacta taaataaaaa accaggtttc tttaaagggt taatgtcaaa aggtcttaat
    31441 aatgatgatg aagaagatga atattttgaa gaagaaaata gtgatggtgt agatgataaa
    31501 actataaaaa tagttggatt taataaggca gaagatgagt atttagaaat attagaagga
    31561 actcaaagta tgccagagtt agatgtttta aaagaattac aaaaagctac caatgaaaat
    31621 ccagttgtag atactaaacc agaaaaaaaa gttgatatag ctaaacctaa tttaaatata
    31681 gaaaaaactc aacctatgag tattgtagca gagccagtta atgaggatta ttcaaactat
    31741 aaaaagccta gcattgagct tttaaataaa gtaaataaga agtctgatga aaatggtaaa
    31801 aagaaagtgt tgaaaaatgc ttctctttta gaaaagacac tatcagattt tggagtggaa
    31861 gcaaaaatta atcaagttac agttggacct actataacaa gatatgaaat acaaccaagt
    31921 ccaggagtca aggtaagtaa aattgtaaat ttaactgatg atatagcttt aagtttagca
    31981 gctaaaagta taagaattga agccccaatt cctggtaaaa gtgcaattgg aatagaagtt
    32041 ccaaatgaag aagctcaaat ggttggtgtg agagaagttc tagaaagtga agaatttaat
    32101 aattttaact ctcctcttgc aatgggactt ggaaaagacg tagcaggaaa aattataatt
    32161 ggagatatag gtaagatgcc acacttacta atagctggtt ctacaggttc aggaaagagt
    32221 gtgtgtgtaa atacattaat aagtagtatt ttatataagg caaatcctga tgaagtaaaa
    32281 ttactattaa tagacccaaa agtagttgaa cttgcaaatt ataatggaat accacatcta
    32341 ttgataccag tagttactga ccctaaaaaa gctgcaaatg ctttaaattg ggcagttaca
    32401 gagatgaata gaaggtacaa attatttgca gatgctcaag taaaagatgt aacaagttat
    32461 aatgagaaag cggaagaaaa acttcctaaa atagtaataa taatagatga gttagcagat
    32521 ttaatgatgg caagtgcaaa tgatgtagaa gattatattt gtagattagc tcaaatggca
    32581 agagctgctg gaatgcactt gattgtagca actcaaagac catctgttga cgttataaca
    32641 ggggtaataa aggctaatat accatctaga atagcatttg cagtatcatc tcaaactgat
    32701 tcaagaacaa tccttgatat gggtggtgca gagaagcttc taggtaaagg tgatatgtta
    32761 ttctatccac ttggtgcagc aaaaccagtt agacttcaag gggcattcat atcagagagt
    32821 gagtcggaaa aagtaatcga ttttgtaaaa agtcaagtta aagatggaat aaaatatgaa
    32881 gaagatataa ttgaaactat atctaaggtt aatacttcaa agggtagtga tgaggatgag
    32941 tttttgagtg aagcgataga atttgtcgtg gaaagtggtc aagcatctgc ctctatgcta
    33001 cagagaagat ttaaaatagg attcaataga gcagctagac ttatagattc tatggaagaa
    33061 agaggaataa ttggagcaag tgagggaagt aaaccgagaa aggtattaat aagcaaacag
    33121 gatttgcaga atttagaagg tgaatagaat tgtcagttat aaaaatagaa aaagcactta
    33181 agctagataa agtaatattt gtagatgtga gaactgaagg agaatatgaa gaagaccata
    33241 tattgaatgc aatcaatatg cctcttttta aaaataatga acataatgac gttggaacaa
    33301 tttataagat gcagggaaaa catgaagcaa tacaaaaagg gtttgactat gtatcgtata
    33361 aattaaagga tatatattta caagcagcag aacttgcatt aaattatgat aatattgtca
    33421 tatattgtgc aagaggcgga atgagaagtg gcagtatagt aaatttatta tcatcattag
    33481 gtgtaaatgt atatcaactt gaaggtggat ataaggctta tagaaatttt gtattagagt
    33541 atctaaggca tgtaatggat acaaaaaact ttgtatctgt tcatggattg actggtacag
    33601 gaaagactga tttgttacat ttattagatg aaaaaggaat agatgtactg gatttagaag
    33661 gcatagctaa aaacagtggt tctacctttg gttttataac ttttgataaa aagccacctt
    33721 ctcaaaagaa ctttgaaaca aaactatttg aaagtatatt tttttcgaaa gagaattata
    33781 tatttgtcga gagtgaaagc aaacgagttg gaagtgttac agttccaaat gaaattttcg
    33841 aggcaatgac acgagaagga catcatatat tattagaatg tgatattgaa aatagagttg
    33901 atagactttg tagagattat atttatgata aagatgaagg taatatattg attttaaaag
    33961 aatgtataaa caagtttaga aaaagattgg gtaataaagt agtagatgat tatattgatt
    34021 tattagaatc aggtgaatat aaagaacttg taaaaagata tcttttagaa tactacgacc
    34081 cactttatat gcattcagta gaaaaatata agtatagtaa gattataaat tttaatgata
    34141 cacaaaaagc tttagaagat gttatagact tatatgagag tatattggaa ggagaaagtg
    34201 aatgttaaaa atagcattag aatcattagg atgctcaaaa aatttagtag atgcagaaat
    34261 aatgatggga attttaaata acaaaggcta taaattaatt ggagattttg aagaagctga
    34321 tgtaattata gtaaatacat gtggatttat agagtcagct aaacaagaat ctatagatac
    34381 gataataaac tttgcagagt taaaaaaaac tggcaattta aagttgttga tagtaacagg
    34441 gtgtctagcc caaagatatt ctgaagaatt aaaaactgaa attcctgaaa tagatgctat
    34501 agtaggaaca ggaagctatc aaaatataga taaaatactt aaagaattaa gtgaaatgca
    34561 taaaattgta agccttaatg atatagagtt tgtatttaat gaagatttac caagatatat
    34621 atctacacct agctatatgg cctatttaaa aattggagaa ggatgttcca ataattgtac
    34681 ttattgtata ataccaaaac taagaggtaa atatagaagt agaaaatttg aagatataat
    34741 taaagaagct aagaaattag ctgaatctgg agtaaaagaa cttgtggtta tagcacagga
    34801 tacgacaaag tacggttttg atttatatgg aaaagaaaga ttatcagaac ttttagaaga
    34861 acttgcaaaa atagatggat ttaagtggat aagggttatg tattcatatc cagaatctat
    34921 aacagaagaa ttgatacaag ttataaagaa atatgataat atatgtagtt actttgatat
    34981 gccaatacag catgcaagta acaatatttt aaaattaatg aatagaaaaa ctactaaaga
    35041 agatatatta aataaaatca atctgataag aagtaatata ccagatgcta tacttagaac
    35101 tacaataata gtagggtttc ctggtgaaac agaagatgac ttcaaacaac ttgtggactt
    35161 tgttgaagag gttaaatttg atagacttgg tgcatttgca tattcaagag aagaagatac
    35221 accagcagat agattgccaa accatataga tgaagaagta aaaatacaaa gaagagatac
    35281 tttaatgatg attcaacaaa aaatatctga agaacttaat gacaaaaaga taggaaaaac
    35341 ttatgaggtg ttaatagaag aacagataga agataatgta tatacaggaa gaacacaagg
    35401 tgatgcagag gaaattgaca gtatagtgta tgtaaaaagt gtagacaatc ttgaagtagg
    35461 agaatttgta agtgttcaaa taaatgatgc aatggaatac gatttaatgg gagatgtttt
    35521 atatgaactt gcctaacaag ttaactttgt ttagaatatt tttaatacca gtatttgttt
    35581 taattatgtt gctcaatata ccaaataaat ttttaatagc ttgtattatt tttataatag
    35641 cttcaattac tgatgcttta gatggaaaaa tagctagaaa atacaatcta gtcactgact
    35701 ttggaaaatt tatggaccca ttagcagata agttattggt tatttcagca cttacatgta
    35761 tgatagaaga ccatcttgta agtagttgga tggtaattat aatagtggct agagagctta
    35821 cagttagcat attaagagct atagctgctg ctgatggaaa agtaattgct gctggaaaca
    35881 gtggaaaact taaaacgata actcaaatgg tatctatagt gtttttattg ttaggtgctc
    35941 agtttgaaaa tgtattgata ttaaatattg gtgaaattct cattcttata gctacactac
    36001 ttacattata ttctggatgg gaatatctat ataaaaataa agagcttttt atgtcttcta
    36061 agtaaaaaat tatgctttaa taaataaaaa ctaatgatta ataaataaaa aataacaact
    36121 taaaatttta aaaatgtaaa aaagggtata ctattatagt atacctcttt tcattttaag
    36181 aatattttct tttgtgtata taattattaa taatggttta taaataaaat gtaatgaata
    36241 aaaatataat cattagtagc gtttttaaat tgactaggtt tgatttatgt tatataatta
    36301 atatataaca agagaacaaa tgtttgtaga taaatgaagg gatggtatag agatgagtgt
    36361 agatcaagaa aaattaaaag cgttgaatga agctttaggt aaaattgaaa aagattttgg
    36421 taaaggttca gtaatgaaat tgggagaagc aacatctatg tctatagatg ttatatcaac
    36481 aggagcgatt ggtttagaca tagctattgg tataggaggt ctacctagag ggagaatagt
    36541 tgaagtatat ggtccagaat cttctggtaa gactactgtt gcgcttagtt gtgtagcatc
    36601 agctcaaaaa gatggaggaa tagctgcatt tatagatgca gaacatgcac ttgacccagt
    36661 atatgcaaaa gctttgggtg tggatgttga taacctaata atatctcaac cagatacagg
    36721 tgaacaggct ttagagatag cagaggcatt gataagaagt ggagcgatag atataatagt
    36781 aatagactca gtagcagcat tagttccaaa ggctgaaata gatggagata tgggtgattc
    36841 tcatgtaggt ttacaagcta gacttatgtc acaagcactt agaaagttaa ctggttcaat
    36901 taaaaaatca aattgtgttg ctatatttat aaaccagtta agagagaaag taggaataat
    36961 gtttggaaac ccagaaacta ctactggagg acgtgcacta aaattctatt catcagttag
    37021 attggatgtt agaaaaatag atacaataaa acaaggtgat aaagttatag gtagtagaac
    37081 tagagttaaa gttgttaaaa acaaagtagc accaccattt aagcaagctg aatttgatat
    37141 aatgtatgga gaagggattt caaaaattgg agacctttta gatatagctg ctgatgtaga
    37201 tatagttaaa aaatcaggtt catggtatag ttacaatgat actaaacttg gacaaggaag
    37261 agaaaatgtt aaaaaattct tggaagataa tttagattta actactgaaa tagatgagaa
    37321 agttagagca ttttacaatt taaatgaaga acatgaagaa tcaggtactt cagtatcaaa
    37381 agaaattgta gaagaataag taaaaataca aaaaaataac tagtaattaa agacatgcca
    37441 cgctccctat tagcttgaca caatgttgaa aaaattataa aattaagtga ggataaaata
    37501 tctaaattta attttaatta ttaggaatat tttttaatca tagtgatgac attttgggat
    37561 tattaacgaa ggaggtggat gtcatagata gtgtagtaat gattgtaata ggtgcagctg
    37621 ttggtattat agctggatat tttgttagaa aaaatatatc tgaagcaaaa attggacaag
    37681 ctgaaaactt ggccaaagaa ataatagata aagcacacca cgactcagaa acagtacaaa
    37741 aagaaaaatt actagaagct aaagaagaga tccataagtg gagaacagaa gctgaaagag
    37801 aaaacagaga aagaagaaca gaagtacaaa agtatgaaaa aagagtagta caaaaagaag
    37861 aagtcttaga tagaaaatta caaaatttag aatctaaaga agtaaaccta agtgaaaaat
    37921 taaaggtagt ggaaaagaaa gaagaagaag ttgaagtaat aaaaactcaa cagttagaaa
    37981 aattagaaag tatatcagga attacttctg ataaggccaa agaaatcatc ttaaccaatg
    38041 cggagagaga tgtaagacgt gaaatgtcta taatgataaa agagatagaa agtcaagcta
    38101 aagaagaagc tgataagaaa tcaagagaaa ttataggata tgcaattcaa aaatgtgcag
    38161 cagatcacgt agccgaaact actgtaacag tagtaagctt gcctaatgat gaaatgaaag
    38221 gtagaataat aggtagggaa ggtagaaata taaggacttt agaaacctta acaggtatag
    38281 accttataat agatgacact ccagaagccg taattttatc aggatttgat ccaataagaa
    38341 gagaaattgc aagaattgct ctagaaaaat taatagcaga tggaagaata catccagcta
    38401 gaattgaaga aatggttgaa aaggcgagaa aagaagttga caatattata aaagaatatg
    38461 gtgaacaagc tgcatttgaa actagtgtac atgggattca tccggaatta ataagattat
    38521 taggtagact taactataga actagttatg gacaaaatgt acttaaacat tctatagaag
    38581 ttgctcatat agctggtata atggctgctg aaataggagc agatattaga ttggctaaga
    38641 gggcaggttt attacatgat ataggtaagg ctgtagacca tgaaatggaa ggtacacatg
    38701 ttgaaatagg tatggattta cttagacgtt ataaagagtc taaagaagtt atacatgcca
    38761 tgagtactca tcatggagat tacgagcctc aaacagtaga ggctgtatta gttacagcag
    38821 cagatgcaat atcagctgct agacctggtg cgagaagaga aactttagaa gcatatataa
    38881 agagacttga aaaattagaa gaaatagcta attcatatga aggtgtagaa aaatcatttg
    38941 ctatacaagc tggtagagaa ataagaataa tggtaaaacc agaagctata aatgatgaag
    39001 aaatacatct attggctaga gatatgacta agaaaataga ggatgaactt gaatatcctg
    39061 gacaaataaa agtaagcata ataagagaaa caagagctat agagtatgcg aagtaaaaga
    39121 aataatatct aaataataag aaaatatttt tagaaattta aatttgccac aagatatgat
    39181 aatatatctt gtggctttta aattgtttaa gtttaatttt atataatgca aaaataatct
    39241 aagtgctaaa agtgctactt acaaaagatt aataaaataa agctttatat atgtattatt
    39301 tatataatta tccaagtttg tttgatataa tgaagttgta aaataaatat attactactt
    39361 ggaatgcttg tacttaaata agatgaaaat acaatgacgc taaagtgagg attagagaga
    39421 gggtacacta tgaaaaaaaa tacactttta catacaaata ttatggtttg cattattatt
    39481 actcttggtt ttgtggctac ctctataatt ggatatcaat ctaataccaa tatttttaaa
    39541 aatgatattg aacatgtatc tacattggct gctgaaggta tttattatca gatagataaa
    39601 ctactttcag aacctataaa tgtatctctt acaatggcaa atgacagtct attaaaaaat
    39661 tttttagatg gtgagaaaga acatttaaat gatgaagaat ttatttataa attacaagat
    39721 tatctgaatg tgtatagaaa taaatattca tatgattctg tttttttagt atcaactaaa
    39781 accaataatt attatcattt taatggactt gatagaaatc ttagcgctaa taactcagag
    39841 aatcaatggt attatacttt cttaaagaat gatgatgaat actcattaaa tgttgataat
    39901 gatgaagcaa gtaacaatag tattacagtc tttgtaaatt gtaagataaa agatgataat
    39961 ggagcaacta tgggaattat aggtgttggg ttaaaggtta attcattaca aatgttgctt
    40021 aaaggatata atgacaaatt tgatgttgtt gcacgcttaa ttgatgataa agggtttgta
    40081 caattagcag tagataaaac cggtcatgag aatataaatt tttttgaaaa ttctagtagc
    40141 gacttgtcta attcgaaaca attaatatta aacaacaaaa aggaacaaaa gagtttttgg
    40201 tattcatctg aaaaatcaaa aagttatatt gtatgtcagt acatacctag tttaaaatgg
    40261 catcttgttc tagaaaatga ttttacttta atgattaaac agcttcatct gcaatttttt
    40321 aaaggcattg cagttatagt tttaattata atatttgtac tttttactat tacacatgtg
    40381 cttaaaaaat acaaaaacca aataataaag cttagtgttt cacagaaatt ggaatatcaa
    40441 aaattgttga gcaaatctac tgaaggtctt tatgaaaata tttttgaaat tgatattact
    40501 aacaataaag ctggttgtga agatgagaat aggtattttc atgaatttgg attagggctt
    40561 aataccccat atgatgaagc cttacataca atagctaaaa accaaatcaa agaagaatat
    40621 gcacaaggtt atttagatac atttttacct gaaaatgtaa ttaaacgtta taatagcgga
    40681 attaataata tcagctatga ttttttaatt aaaaaagatg aagaaagtta tcattggatt
    40741 agaattaatg cacgaatttt cttttggaca tcagatgaat ctgttcgtat gatatcttat
    40801 cgtaaaaata tagatgaaga aaaaaataga gaattactac ttctcgaacg ttcacaacgt
    40861 gattctctta cagggcttta caataaagct acaacagagg aatttattcg ttcattttta
    40921 aaaaatgaaa gtaatcaaga tttagaacac gtttttctaa ttttcgatat tgataatttt
    40981 aaaaatgtaa atgataaata tggtcatgta tttggagact ttgttataag tgaatttgcc
    41041 ttagaattaa aatctcaatt tcgtgaggac gatattgtgg gacgtattgg tggagatgag
    41101 tttgtagtat taataaaaga ctttaataat aataactatg tgcttataga caaattagag
    41161 cgtttttgtt ctaagattaa tcagaaaaaa tttgttgagc aagcagaatt ttctattgca
    41221 tgtagtattg gtgtagcaat gtatcctgaa catggatatg tatactctga actatatgag
    41281 aaagcagacc aagcacttta ctatgcaaaa agccatggga aaaattctta tcatatattt
    41341 tcagaggatt ctattgatag tatttcattt catatagact ctagagatat aaaagtatta
    41401 ttagaaatgg ctactgatgg tgttgtcaaa tttgcttgta tggaaaactt aaaattactt
    41461 tatttcaacc aaaaaatgct tgaatttact ggatattcag ctcaaactgt tacttctata
    41521 ggttttgata ttttttcgcc tgtattacaa gacgacttac aaatggtact agatacatta
    41581 agagaagcaa tttctaaaag agagactttt gaaatagttt ttcgtttttg tcatacagat
    41641 ggtcatattt ttcctgtaag gatgcaaggt aagtttgtaa gtgaattata tcaaaatcgt
    41701 tatcctgttt tttatgcgat ttatacagac atatcaagta tcaatacttt actagaaaat
    41761 aaatagtaaa tactacagta aaatctaaaa ataggatata atagtattaa tataagaaga
    41821 ttataaataa aacctgctaa tgaaaataga ttatttttag caggttttta aattttttat
    41881 aataaatctt atttttggct aacaagattt atttttttta agactttact tattatttta
    41941 agcattaatt atgaaattta tcattttatt atttacagaa agtattttat aacaataaat
    42001 atctatactt attgcaaaat ttttttagca gttttgtatt tatttgtatt tattttgaat
    42061 ttatttacta aatttgccta taaaaagtat atataaaaat atagttcaaa atggtataat
    42121 taagtataac agaaggaggt aatgtaagtg agccaataca taaatataaa ttctcagtta
    42181 gacgccctaa aattgaagga gttcgagaaa atattttacg aaaatatcaa tgaggacgtt
    42241 aaagtagtgc caaaagttac tccttttaaa ggaataaata ccgatttgtt gtatgttaaa
    42301 gatggaagaa ttttatttat aaaatttatg gatacaacag aagatatatt ttttatttta
    42361 gaagaagagt tacttgaagt tatgaatgag gaatatgaac ttttgaaact aaaaatggga
    42421 caaaagaata gaaatataag ttataactac gtttacatta tgccatacgt tgaagttgag
    42481 gaaacatatg aatttgaaga atttgttaat aataatataa tagataaaaa taagcttcaa
    42541 gatataatga ataagggttc gctggaggaa tatcttaatg atgagaatga tgaaataaac
    42601 ttaaatttat ttttactaga catatgttca gaatactata taataaatga taaacttcat
    42661 ctaaatgaaa aatttaaaaa aatttcattc tacaatgatg actataagta tacagcaact
    42721 atgatggaag acgttcaaat taaagatgtt gtttctatta aatatgggaa tacacttatt
    42781 gaaggtggtt ctggtatagg caaaacagca attatgcttt ctagggctat aaaattagca
    42841 aaagtatatc cacatcataa attagtcata tttacacata caaaacaact gtgcaatgag
    42901 cttcgagaga ggatagagtt attatacaaa gataataaca atttagaagt tcacacattt
    42961 agttctttta tatttaaact agctaaaaaa ttcaatttaa ttgtagatta taacatgtta
    43021 aaaaatgatt acgaaaagac ctttaataat cttgtaaaac aagcacagaa cattataaaa
    43081 aataaaaata tgttcaaggc tatttttatt gatgaagcag aaagcttttt agagtatgaa
    43141 atagatttta taagggagtt tttatataaa acaaaattca tatttaatgt gtgttcttgt
    43201 aactccttga atatctctaa tagattgaat atatttaaaa aattatataa tggtatagaa
    43261 tttgatgata agattatctt aagtaaaaat tatagacaag ctaaagagat tgtagatttt
    43321 acaaataaat tttcaaataa ttctaactca tatatcaacg aattaagacc aaatacagaa
    43381 tttagtactt tcttttatac taaagcactt agaggtggaa ataagtctgt tgatataata
    43441 aaagtaagtg accttgatga ccaaataagt tctgtaatct gggaaattga gtatttaata
    43501 agtaaaaaag gtcttgatta ttctgaagtt gctatcgttt atccttacaa taagaagaaa
    43561 ttaaaaagtg gaaaaaccat ttactttcaa tatatgttaa aaaaagcatt ggaagaggca
    43621 aaaattcctt atatatgtgc agaagataat ttgacaaata taagtaagaa ggtaggaact
    43681 acaatagcaa atatatatgc aataaagaat ttagagtata aagcggtaat agtatgtgaa
    43741 ttagagatgt tatacaatca aactataaat gatattgaac aagattatca agtaaatgac
    43801 tttgtaggag atttaaataa ggtttattta gctatgagta gagcaacaga ctacctaagt
    43861 atagtaacaa cttttaatga agaagcaagt gatataataa gacttattac agaatcaaaa
    43921 gatatttagt aaaaaaatat ttgtaattta agaaaataaa aagagactga gatttgtaaa
    43981 ataaacttta ccaattcagt ctcttatttt ttagtctact ttcccaatat tatcaagagg
    44041 taatagtctc accataacct taccaagaac ttcatcttca tcaaccatac ctacatcagg
    44101 gaatctacta tcattactat tttctctatt atctcccatt gcaaatagtt taccttttgg
    44161 aacaacagta tctatatctc cagaagtata gttattgtgt atatatggtt catttaataa
    44221 ttttccattt acatacactt tagaatttga tatttttatt ctgtcacctt cagtagctat
    44281 aactcttttt attaagtctt ttttctttcc tgtttctcca tcaactaaat tggttttaaa
    44341 aactacaata tcgccttttt caggtttacc aaccttgtat gatatcctat ttaaaatcag
    44401 ataatcttta tcatctaaag taggatacat tgattctcca cttacaatag aaggtcttat
    44461 aaattgtaga attacaaatg caagtacaat agccatagct attgacttaa tccaatcaaa
    44521 tatttctttt ttaacactca taacttttct ccttatcatt tgttattaaa ttagaataca
    44581 ttataataga aagaaataag caagaaccac tatacccaag actattctat aataaccaaa
    44641 tactttgaag tcatgttttt tgatatagtc cataaaaaat ttaataacta caattgaaac
    44701 aacaaatgct actacagaac caacacctaa aataagccat tcaaatccag taaatccaaa
    44761 tccagctttt agaagtttta atgcactagc tccaagcatt gtagggatgg ctaagaagaa
    44821 tgaaaactct gctgctacat atctagaagt accaagtaat actgcaccta ttatagtaga
    44881 accagaccta gatgtacctg gtataagagc tagacactgg aataatccta tacaaagagc
    44941 taatttatat gtaacttgag aaaaatcttt atacttaggt tttttatttc tcttttcaag
    45001 ccctatcatt attataccat atacaataag agcaatagca actactgttg aattaaagaa
    45061 taatctatct atatcatctt caaacagtat tccaataact ccagatggta taactgcaat
    45121 tataacctta agccataaac ggactgtttc ttttttctgc ttaatattct ttgcgctatc
    45181 aaaaggattt aattttctaa aaaatataac aagtacagct aatattgaac caaattgaat
    45241 tacaactaaa aatgtactta taaatgtatt tgaaaaattc aattttataa actcatcaac
    45301 taatatcata tgccctgtac tacttactgg tagccattct gttattccct gaactatgcc
    45361 caaaatgact gccttaaaaa tttcaagcaa actaaatgtt tccaaatcaa aatacctcca
    45421 atacaaattt atagtagcat attttattca tagattaata aaaaaatgcc accttttact
    45481 aacttataat accatagtac tgtgtagtgc acaatggaag attgatattt tcataaaacc
    45541 ttcataatat aacaaaataa acttaaaagt tatctattga ataaggggta tatttgaggg
    45601 ggaaatatat ggtatagtaa aagtatagct attttatttt atgaaaagga aaggagttat
    45661 tatgtatagt acaaaaatac tagatgatta tgagtatgaa acttttaatg ttttttctac
    45721 aaaattaaat ccaaacacga aacacgatta tttatcaaag gttatactgt ttaaagaatt
    45781 tttaaaaggg aaagaattga tttatgctac gaaagaagat tgtaaaaatt ttgtagacta
    45841 tatacagact aaatatgcga aatcaacttg tgaaaagata tatagttatt tacatagttt
    45901 ttataacttc ttaaaaaaag aaggatacat agatataaat ccatttagat atgtagaaaa
    45961 acccacagta acaagaataa aaacaaaaga tgatgttcta agtatacaag aaataaataa
    46021 acttataggt atcctaccaa aattaaatat aagagataga gtaataatag tctgtctagt
    46081 tactactggg tgtttattaa atgaattagt tagcttaaag tggaaagacc ttatggtaga
    46141 tgaaaacgat aactcatatg taaggttagg taagggaaga aaagaaagag tagttaaatt
    46201 acatccatac ttttttaaac ttttagaaga ttacaggaat tattctgggc ttccagaggt
    46261 aataatacct agtgatgatt ttatttttac aactcaaaag agtaattcta taacagatag
    46321 aaatgtcaga cttatagtca aaaaagcatt agatttagct ggactttctc aatattcagc
    46381 aagagatttt agacattcat ttgcagcaat aagtttaagg cttggggcag atgaaagtga
    46441 tgtaaaaaat cagcttggat ggagtgataa atactatgca attagatata agtatgtatt
    46501 aaattttgtt gatagtgaaa tagtggatta cttaattgaa aaagataatt tggatataaa
    46561 taaaaaatag taataaataa aaaatactat atataaatgt gaacaaaaaa taaaaaagtc
    46621 ttgttatagt tcgtaaaatt atatataatt atttatgtac taatgtgtac acagtaatca
    46681 cacgacaaaa gatttaagga aggtgctaat ataatgatag ataataaata tactacttac
    46741 tcaaacccac ttacagacag atattgtagc aaggacatga gttatatatt ttctccacaa
    46801 tttaaattct ctacatggag aaggttatgg gttgcacttg cagaaggtga acatgagtta
    46861 ggaatcaata taactgaaga acaattagat gagctaagag ctaatataga taatataaat
    46921 tttgatgaag ctagaaaaat agaaaaagaa gtaagacatg atgtaatgtc tcacgtaaaa
    46981 gcttatggtt tacaatgtga aaaagccaaa ggaataatac atttaggagc aacatctgca
    47041 tatgttggag ataatacaga tgttatacaa atgaatgaag ctttaaaact tctaagagta
    47101 aagcttgtaa atttaataaa caatttaaaa gaatttgcac ttaagtacaa agatatgcca
    47161 gctcttggat ttacacactt ccaagctgct caacttacaa cagtaggaaa aagagcttgt
    47221 ttatgggctc aagatttaat tcttgatttg gaagatttaa actatagaat agacaacatg
    47281 aagttaagag gagttaaagg tactactggt actcaagcaa gttttttaag cttatttgaa
    47341 ggagaccacg aaaaagtaaa agagttagat aagaaaattt gtaaaaagat gggataccat
    47401 tcttcctatg cagtaagtgg acagacatat actagaaagt tagattatca agtaataagc
    47461 atactatcag ggatagctca aagtatgcat aagatgacta atgatataag acttttacaa
    47521 agtttaaaag aattagaaga gccatttgaa aaaaatcaaa taggttcatc agcaatggct
    47581 tataagagga atccaatgag aagtgagaga atagcatctt tatctaagta tataatctct
    47641 gaatctataa gccctgcaat ggtacaagcc actcaatggt tagagagaac attagatgac
    47701 tcagccaata agagattggc aatacctcaa gcatttatgg cagcagatgc tatacttgaa
    47761 atagggataa atgtaactga tggtttagta gtatatgaaa atatgataaa tagacgtgta
    47821 aatgaagaac ttccttttat ggctacagaa acaatactta tggaagctgt aaaaagaggt
    47881 ggagatagac aggaattgca tgaaataata agagaatatt ctatgaaagc tgcctataga
    47941 gtaaagcatg aaggcaagga taataactta attgaactta taatgaatga tgattcattt
    48001 aaaatgagca aggaagaaat actatctata atggacccaa aaaactttat aggtagagct
    48061 ccagaacaag ttgtagaatt tgtaaatgaa gttgtagaac ctgctataaa agattataag
    48121 gaagacttag gaaaagtaga tgtagaccta agagtataga attgtacaga taaaatataa
    48181 ttaaaaacgg ctatcttatt tataaataag atagccattt taatgggcta gcgtcttctc
    48241 tccaccgctg tgaagagttc ttctttactt actataccat gaatttaata aaatagctat
    48301 ataaataata tttaatagga ataatataaa taaaaataaa aaaatgataa gattactaat
    48361 taaatttaaa cattcagcaa aaactattgt acttgcaata tttttaatgt aaactgaaat
    48421 aaagttattt agataattta ataaatttta aaacaaccga ggtgattata tgaactatat
    48481 agtaaaagat accataagtt ttttagtaaa aacatttcct aagatttatt ctagcctgta
    48541 cttagaagac ctaaaaaaat ttgcaccaga ttataatgta aataaaacac aattaagagc
    48601 attagttttc ataaaaaatt atggagtaat aagtatgact gatttatgct ctaagttaaa
    48661 tatagaaaaa ggcagtttaa ctagtatggt tgatgattta actgataaga agtatgtaac
    48721 aaggaaaaga gatttagttg atagaagaaa atatctaatt gacattactg aagagggaga
    48781 taagatagca actgatttta tggataaatt aagtgatggt ttaggagaaa aactttctaa
    48841 attaactgaa gaagacagaa aaaaatattt agaagcaata aatactcttc aatatatatt
    48901 aaacaaagaa gaatttagat agaaaaaata taaaaatttt tgtatttaat ggtactaaga
    48961 ttaattcttt gttattcatt taactatata attataagtc taaatacaat ctaaaaagta
    49021 catcttaaat tttcttgatg tactttttta taatttctct aactaaggca agacaagttt
    49081 tagatgcttt aattaaagtg aataaagatt actggccaac actatataaa gaaaatgaaa
    49141 aatagtcagg tctaagtctt aattaatata ttaattaaga aatgtcccct tttcaaataa
    49201 tatctgaaaa ggggacattt tatatcatta aatttatata aattaagttt aaaaaattat
    49261 ttttgtaaag ctacatattg ctctaaacct tcttttaata atgtagcagc tctatgaagg
    49321 tctttttcat ttaagatgta agctaatctt atttcatcac gtcctaaacc tggagtagca
    49381 tagaatcctt cagcagggca aaccataact gtttcattat ctttattaaa ttcttttaac
    49441 atccaaattg tgaaatcttc tgcattttca actggtaatt tagcaactat atagaaagca
    49501 ccagttggtt ttttacatat aacaccttca accttcatta attcattgta taatacatct
    49561 cttctttttt tgtactcttc attaacttct ttgaagtaag aaacaggagt tttgtataac
    49621 tcaacagctc ctatttgctc taatgtagga acacaaagtc ttccttgaca taatttaagt
    49681 atttgagcga taagaccttt atttttgcaa gcgatagaac caattctagc accacaagca
    49741 ctgtatctct tagaaacact gtctattatt ataactctat cctgtacacc ctctaagtta
    49801 ccacagcttg tatactcaag cccatcataa acaaattctc tataaacttc gtctgctatt
    49861 atccataaat ctttttcttt agctatttca gctaggatat taagttcttc ttttgtataa
    49921 attgcaccag ttggatttcc tgggttagaa agaattatag ccttagtttt atcatctact
    49981 ttagacaata tttcttcttt agatggaagg tggaaaccgt tttctgcctt tgttgtaaca
    50041 gcattaactt ctacgtttac agattgacca aatccattgt agtttgtata gaatggttct
    50101 ggaactaata gattatctcc tgggtcacaa actgccatca tagtgaaaag taaagcttca
    50161 ctaccaccgt tagttactaa taattcatct ttttcaaaat tcatatcgta agttttatag
    50221 taattttgaa gtgcttctaa taattctgga ataccttctg atgtagcata ttctaagact
    50281 tcgctatcaa agtttttaac agcatcaaaa aatcctttag gagtttttat gtctggttgt
    50341 cctatgttta agtgatatac tttgattcct ttatcttttg ctgcttgtgc aaatggaaca
    50401 agttttctga ttggagaggc ttgcattgca ctaactctgt ttgaataatt cattttaata
    50461 ccccctattt aatttaaata cgtatattgt attatgtaaa ttgtatgttt gaatacaaga
    50521 catctttaca agataataat aacatactta tgggtaaaaa tcatcaaaaa aaattaatat
    50581 agctttaaaa taaactttta acaaattata gtaaaatacc catgtttatg ccactaaatt
    50641 atgtattcat aaattaattt atagtaagat aatattctga tgtactgata gtgatttttt
    50701 agttataatc tttcagctat agacaaaata tataataata aatatgcaaa attataaaaa
    50761 atattataaa tttatttaac agatacgata aatatcatat aattatatta aaggctatta
    50821 actaagaggt gttaattatg aaagaattaa gaatagatcc aattaccaat gatgttgtta
    50881 tatttgctac agataggtta aaaagacctt tagatacagc agatatccca aatgaagatg
    50941 aagaaactaa tgaatatgat gaagaatgcc cattttgcaa aggaaatgaa gctcatgcaa
    51001 ctgatgcatt atttgaaata gatagtgaag aaggatggct tgtaaaatct gtctacaata
    51061 aatttcctat aattgatgat atggcaagag atgtatatgg tgttcatgaa gtaatgatag
    51121 agagcgataa acataatcgt agtttttata acatgagtca aaaagaattt gaagatgttt
    51181 tttttatgta tagaaataga tttagagatt tgtcgaaaga tgataaagta gagtatgtta
    51241 gtatcttcaa aaacttcttg agaaaggcag gagcatcttt gatgcatcca catgctcaaa
    51301 tattgtctat gtcttttatt ccacctgaaa ttacgaatga actgttggtt tcaaaggagt
    51361 attatgacag caataaaagc tctttgtatg atgatttaat agaaaatgaa ataagtttag
    51421 atagaagagt tgtttataat ggagaagctt ttttggtact tataccatat gcaaccaagt
    51481 atagtggaga agtaagaata atatttaaag ataaaataga gtttggtgag ttaaatgata
    51541 ataatataca ggagctttct acaatatttg aaaagttgtt taagaagtta tacaatatca
    51601 atggatatat gccatttaat ttatgtattc acactcatcc aacaaagatt gaaacaaaat
    51661 cgtattttaa tgttcatatg cacataatcc caagaaaata taattttgga ggatttgaac
    51721 ttggaacaaa tatgtatgtt tcttcaatga gccctgaaga tttaacaaaa aagttaaaaa
    51781 ttgattaaaa catatatttt taggtattaa gtaaatagta attttagatg aaattatagt
    51841 atagcattgt taaaataaaa gtaaattaag aatttacaat aaaattgttg aaaagccccc
    51901 atctttagct atggggagtg tgtcaatgtt tagatgagga gtataagtat gaaatttata
    51961 tcatggaatg ttaatggaat aagagcttgt gttgggaaag gatttttaga ctttttcaaa
    52021 gaagtagatg cagatatatt ttgtttacaa gaaactaaat tgcaagaagg gcaaatagag
    52081 ttagatttac caggatattt tcaatattgg aattatgctg agagaaaggg ttattcaggt
    52141 actgctatat ttacaaaaaa agagccttta aaagtaatgt atggaataaa tatagaagaa
    52201 catgacaaag agggtagagt gataactcta gagtttgaag atttttactt tgttacagta
    52261 tatacgccaa attctcaatc tgaattaaag agactagaat atagaactag atgggaagac
    52321 gactttatag attatttaac caaactagat aatcataagc ctgtaattgt gtgtggagat
    52381 atgaacgttg cacataaaga aatagattta aaaaatccta aaaataatat gaaaaatgca
    52441 ggttttacta aagaagaaag agagaagttt tctaaattat tagacagtgg gtttatagac
    52501 acatatagat attttaatcc tgataaagaa ggtgtttata gttggtggtc gtatagattt
    52561 aatgcaagaa aaaataatgc agggtggaga atagattatt tttgtgcatc caaaaaatta
    52621 gaagatagat tagtaagtgc ggatatacac actgaaatat taggttcaga ccattgtcca
    52681 gttgaattag agataaaata aaaattaatt atgataaaaa ttgggctgta gatataaatt
    52741 taaagttaac tagtttttta atctacatgc ctatttttta tctaaataaa ctctatttgt
    52801 tttttctttg cttaacattt tctaatgtaa attgatttgt tttccacata ttataagcta
    52861 agttaatgat ttttttctcg tctttagtta attcacgatt taaaattttc ctaaattcat
    52921 caaataactt atcataatca actctttttt tgttagaata tcttatagtt ttaggtttta
    52981 tactcgtata aagatatata tctgggacta tacttggatt gtatatctta ataaaaactt
    53041 tagcagtata atatgcatca tttaaagcat tgtgataaga cattttttca tcaagttcca
    53101 atatagaaat agcattttgt aggccaatgc tttttcctgc tggattattg aaatatttag
    53161 atgcatgttg ttgtatatta atataagatt taggtaagga atttgatggt agcttgtgat
    53221 agttgatatt cctgtataat tccttcaaat ctccagctcc ccaaacacat aatatagggt
    53281 cttgtgatga tataaatttt ataaaattgt tgtagacctc agggaaagta ggcgaatcat
    53341 taaaatcaga acttttaata ttagtcatac gactaataaa gggatgtatg tctttataaa
    53401 ttgtaggttt tacatagcta ttaaacgtat ctattatatt gaatttagaa tccaatttaa
    53461 ttgctcctat ttgtataatt tcaaaaggac acttttcatt ggatacagtt ttattgagtt
    53521 ttttatcaaa tccttggtta aattccaaat cgaaaattat gtattccata aagtttatct
    53581 cctaaatttt tttattattt cttttactat agattatatt ataaataaaa ttaaattttc
    53641 aaataaaaat actttt
//
LOCUS       DAYAOO010000018        53277 bp    DNA     linear   BCT 12-OCT-2024
DEFINITION  TPA_asm: Clostridioides difficile isolate ST8-SSI-h139-18
            SAMN40601845-rid21577343.denovo.018, whole genome shotgun sequence.
ACCESSION   DAYAOO010000018 DAYAOO010000000
VERSION     DAYAOO010000018.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN40601845
            Sequence Read Archive: SRR28438827
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 53277)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 53277)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-MAY-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-MAY-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002157583.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002157583.1
            Genome Coverage       :: 163x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/11/2024 16:19:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 4,038
            CDSs (total)                      :: 3,963
            Genes (coding)                    :: 3,930
            CDSs (with protein)               :: 3,930
            Genes (RNA)                       :: 75
            rRNAs                             :: 6, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 60
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 33
            CDSs (without protein)            :: 33
            Pseudo Genes (ambiguous residues) :: 0 of 33
            Pseudo Genes (frameshifted)       :: 7 of 33
            Pseudo Genes (incomplete)         :: 25 of 33
            Pseudo Genes (internal stop)      :: 11 of 33
            Pseudo Genes (multiple problems)  :: 8 of 33
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..53277
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN40601845-rid21577343.denovo.018"
                     /isolate="ST8-SSI-h139-18"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Denmark"
                     /collection_date="2018"
                     /collected_by="Statens Serum Institute"
     gene            127..966
                     /locus_tag="ACGI5H_001205"
     CDS             127..966
                     /locus_tag="ACGI5H_001205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438582.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HFG9696918.1"
                     /translation="MKDYYKIGEISKIYGIGRDSLMYYEEIGILRPVRDINGYRMYNI
                     SDIWKLNLIKEFRSLNFPMKKIKEYLDDRSIESTKNILNEELDLIDKKIAEFISHKEN
                     IIKRLSSIESVIQNTKIDEIEVVYIEKRKALELNADIKRDEDFDFLIQKLQKEYEDRF
                     NILGNNNIGSAFSTEAINKGIFNEFKSVFCFLESNEKVYNIVFDEGYYVTLNYTGSNS
                     NNKMYMEKVFKFIEENNYKIIADPIEIYKIDIHETGIVEEFVTEIQVPITKYLYFNGL
                     DGK"
     gene            1081..1320
                     /locus_tag="ACGI5H_001206"
     CDS             1081..1320
                     /locus_tag="ACGI5H_001206"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438585.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9696919.1"
                     /translation="MKCSNCGSVNIEKGILTTGGIYAETIGLKYRGDGKLDKVINKTF
                     PVQSTIYSDLCLDCGEIVRTYIKDNTDRNWCKDKK"
     gene            complement(1491..1667)
                     /locus_tag="ACGI5H_001207"
     CDS             complement(1491..1667)
                     /locus_tag="ACGI5H_001207"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9696920.1"
                     /translation="MFRDEMDKCTHMLTAYISSLYDYCDFIDTQLDDFILEYGENVVE
                     SCLHQVMVLVSKYN"
     regulatory      complement(1721..1817)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF01051"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="cyclic di-GMP riboswitch class I; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /bound_moiety="cyclic di-GMP"
                     /db_xref="RFAM:RF01051"
     gene            complement(2172..2846)
                     /locus_tag="ACGI5H_001208"
     CDS             complement(2172..2846)
                     /locus_tag="ACGI5H_001208"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419842.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MgtC/SapB family protein"
                     /protein_id="HFG9696921.1"
                     /translation="MNHHILIQFEYIARIITAGFCGALIGYERKNRLKEAGIRTHFIV
                     ALASALIIIVSKYGFNDIVGTPGIGLDPARVAAQVVSGIGFLGAGLIFIRNQSVSGLT
                     TAAGIWATAGTGLAIGSGLYLVGIVSSIIIVIVQITLHRDRKWMKLPTAEQVSLKISN
                     STDSIEYIEGKFKKSNIEIINMNIKRLDGDWLEVVIYTKLPKGYKKTNLLKLFSDNPL
                     IETLEI"
     gene            complement(3066..3620)
                     /locus_tag="ACGI5H_001209"
     CDS             complement(3066..3620)
                     /locus_tag="ACGI5H_001209"
                     /EC_number="3.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889225.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine hydrolase family protein"
                     /protein_id="HFG9696922.1"
                     /translation="MSIALILIDIQNDYFKNGKCELFQSEETAENAKKILLFFRKNNL
                     PVIHIQHISTDKTASFFLPNTHGSEINKIVFPLDNEEIIIKHTPDSFFETDLQSILEK
                     KNITNLVICGMMSHMCIDTSVRTAKKLRYDITLISDACTTKNLSWNNIEINANTVHQV
                     FMASLQNSFADVKNTDKFLSNYYK"
     gene            complement(3698..4063)
                     /locus_tag="ACGI5H_001210"
     CDS             complement(3698..4063)
                     /locus_tag="ACGI5H_001210"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429379.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="winged helix-turn-helix transcriptional
                     regulator"
                     /protein_id="HFG9696923.1"
                     /translation="MKIRAEYTCPLEIVHDIIKGKWKTILIFELRQSNKTFSELQHNI
                     YGINQKMLIQQLKELRDFGIIDKISSAGYPLHVEYFLTNRGKKMLKAVEIMQEIGIEY
                     MLEHGQQEILDNKGICYNK"
     gene            4294..4428
                     /locus_tag="ACGI5H_001211"
     CDS             4294..4428
                     /locus_tag="ACGI5H_001211"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429381.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9696924.1"
                     /translation="MNISRKAMKIIELAQKIANKRGISVEEAWSEAVTEYKNKYEHIA
                     "
     gene            4528..5313
                     /locus_tag="ACGI5H_001212"
     CDS             4528..5313
                     /locus_tag="ACGI5H_001212"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896340.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HFG9696925.1"
                     /translation="MIVKIDNTLEKEFWQYVSHEESLNLFIIGYVENYGFSSQYQDIW
                     SQVEGGNITSIILKNKSTLIIYSFKNNFNIGEMKNHIKDLDVESISGKKCVIDRLISK
                     YKDFYEKLDNKFCVLKEIKEIDFSNMKEYKIENAQEKDIDEIGKLLNRSDYKVSKNYI
                     EERKVHLKEGNVRAYFIRNDDTMISTVSTGMETSFLAMVVSVSTDKRYRGKGLASYMV
                     YNLSKELLLEGKVPCLFYNNDVAGKIYHNIGYKEINEWTILFK"
     gene            complement(5410..6234)
                     /gene="pdaA"
                     /locus_tag="ACGI5H_001213"
     CDS             complement(5410..6234)
                     /gene="pdaA"
                     /locus_tag="ACGI5H_001213"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438596.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016810 - hydrolase activity, acting on
                     carbon-nitrogen (but not peptide) bonds [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="delta-lactam-biosynthetic de-N-acetylase"
                     /protein_id="HFG9696926.1"
                     /translation="MKKDSLKKYIMIGAFALTLFGIASINFKSLDKTKTQISSPTLDT
                     HEYDWYFNPREDGKQPSPIKEADFFKKYGAYYVGNPNEKVIYLSFDAGYESGNTPKLL
                     DTLKKHNAKAQFFVVESYIKSNPELIKRMEKEGHLVCNHSKSHPSMAGITDFEKFKEE
                     ITSVEKAYKDVTGKEMPKYFRPPMGKFSEQSLKYTQDLGYKSIFWSFAYVDWYEKKQP
                     THEFAKNKIYSRTHPGAIVLLHPNSSTNTEILDEVLTHWEKEGYKLKTLDYLNNKK"
     gene            6455..9574
                     /locus_tag="ACGI5H_001214"
     CDS             6455..9574
                     /locus_tag="ACGI5H_001214"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003676 - nucleic acid binding [Evidence
                     IEA];
                     GO_function: GO:0004386 - helicase activity [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016818 - hydrolase activity, acting on
                     acid anhydrides, in phosphorus-containing anhydrides
                     [Evidence IEA];
                     GO_process: GO:0006139 - nucleobase-containing compound
                     metabolic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="helicase C-terminal domain-containing protein"
                     /protein_id="HFG9696927.1"
                     /translation="MDNIISVLNDVVFLDIEVSGLDCLNSEILEVGAVKVKDWKIYTY
                     ESLIKNKFEVPIEVFSVCKNLDKNDLEIANKIELVEDRLVNFVEDSFIICHDLSLKKK
                     FFEYHMPKLKNKFIDLIELAVILEPYHKDYSLEYLKNTLTNCNSKVENRALSDAIDII
                     NIVNCLLVKFNNYEKTTLEPLSFKINSYLKKFNLPTWEWSKFLEEANYDLSNNINIKK
                     EYNIFDSKEEKKKERETLKILNEEEKNYEELLKYKTIWENKEGFTYEYRPGQYELTKT
                     IRELFRNSEDEEKIACIEAPTGIGKSVGYLLPAILEARINKKRLLISTDTKELQIQLI
                     NKDIPNVLDSLGLNGKVSYGYIKGKNNYICIDRLEAYIDDYESQNPTKGEILSLIFLK
                     RLVEGGKYGDIEEINYLVFDNFKEISTHLRNVSCDPNMCRPKKCKKDCLYKNRIEELK
                     EEHITVVNHSLLAKWPYKDEKPLENIIVDEAHNLTEKGYDFFSSIINSKSLRYLLQEI
                     YPYEFIQNSSFIYKKYSRNMRKIKAFDKFYNVLKIGREDKQKIARSINFIIEEIDSIL
                     KFGNCNEYNNVSNYNLRWELNLQIDEIVGKLKKDGIDTEISYRAYSEKIKLSCEKIIK
                     NLVSIIIIIYRNIDDDSIDKEADIYKFGKAKTRDLEDIKIIFEIFLEYDEKDDYARIV
                     EIDKNYNDFEFRVVPLKIADLFEENILSQLEKGIFLSATLSLSESMSYFKNTLGIDRV
                     KNVEKIIEPIFDYKNRVSVVGFSDICEYRNSEFPNEMSKIISNISKITEGHTLALFNS
                     KDRQEKTYEILKKYLHSFNLEIYADKKGIRHLNDLNRKCVVLGSKGCFEGVDIPGDGL
                     VCVTLDKLPNLNPKDPLYFTIMKKYGIDYYTINYPQMTIKVKQAMGRILRSKYDYGCF
                     VIFDVGTNISVLKRLEKDLHDCKISKVNSNEFYTYIRRHLNKSRSLILKSVIFDTIKA
                     LNVDAKMDNNDVDKDIIKKDINENIRQRAVKGEVYHIDIIKKDMKVKYFDRNYLINLD
                     IFMREEDKN"
     gene            9592..10191
                     /locus_tag="ACGI5H_001215"
     CDS             9592..10191
                     /locus_tag="ACGI5H_001215"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419848.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="viroplasmin family protein"
                     /protein_id="HFG9696928.1"
                     /translation="MAKQKFYAVKKGKNIGVYNTWDECKKQVNGFSGAEYKSFSTFQE
                     AKEYIDGSEKLSFQEDKEFIEAYVDGSYEHSVKMYGSGVVILKNNEVIKTYSEKGKEK
                     TLVSMRNVAGEIEASKIAMQYCIDNNVQNLILYFDYEGIEKWCTGVWKTNKEGTIAYK
                     NFYDSIKNKLNVKFTKVKAHSGNKYNEEADKLAKKAIGV"
     gene            complement(10418..12547)
                     /locus_tag="ACGI5H_001216"
     CDS             complement(10418..12547)
                     /locus_tag="ACGI5H_001216"
                     /EC_number="1.11.1.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429391.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008379 - thioredoxin peroxidase activity
                     [Evidence IEA];
                     GO_function: GO:0051920 - peroxiredoxin activity [Evidence
                     IEA];
                     GO_process: GO:0098869 - cellular oxidant detoxification
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="peroxiredoxin"
                     /protein_id="HFG9696929.1"
                     /translation="MPNLPSLGSKAPDFKANTTNGPIRLSDYKGNWIVLFSHPGDFTP
                     VCTTEFLCFAKYYDEFKKRNTELIGLSVDSNSSHLAWMYNISLLTGVEIPFPIIEDRD
                     MRIAKLYGMISKPMSDTSTVRSVFIIDNNQILRTILYYPLTTGRNIPEILRIVDALQT
                     SDRDNIVTPANWFPGMPVILPYPKNYKELKNRVNSCNKKYSCMDWYLCFVPDNYNDEE
                     VSKKIDNTCSWKKEHTKNIENECNCEHEHHDYLNKALDCKQEHKTDIKDDCNHEKKHT
                     KNTNKVHNSKQDKFKDKSCDEMNFNYDKDESCDKINSSYNKEDSSYEDFYKHNYKNYD
                     YTSEKNTKKIAMKTLKDSKKLVRPQITDPYNPIVENANCPDINPIVAEYVLGNPTNVD
                     AQLLDAVIFAFAEIDQSGNLFIPYPRFLNQLLALKGEKPSLKVIVAIGGWGAEGFSDA
                     ALTPTSRYNFARQVNQMINEYALDGIDIDWEYPGSSASGITSRPQDRENFTLLLTAIR
                     DVIGDDKWLSVAGTGDRGYINSSAEIDKIAPIIDYFNLMSYDFTAGETGPNGRKHQAN
                     LFDSDLSLPGYSVDAMVRNLENAGMPSEKILLGIPFYGRLGATITRTYDELRRDYINK
                     NGYEYRFDNTAQVPYLVKDGDFAMSYDDALSIFLKTQYVLRNCLGGVFSWTSTYDQAN
                     ILARTMSIGINDPEVLKEELEGIYGQF"
     gene            12771..13061
                     /locus_tag="ACGI5H_001217"
     CDS             12771..13061
                     /locus_tag="ACGI5H_001217"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012816126.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9696930.1"
                     /translation="MSGLKKILRILVISMMICFAMTFALVLINSVMGVHIGLDYYFLM
                     GSVLTVCLTIGIVLCNARKIFDSKAIHKTRTKTVSNNKKQKSHSRDIKRKIS"
     gene            13227..14618
                     /locus_tag="ACGI5H_001218"
     CDS             13227..14618
                     /locus_tag="ACGI5H_001218"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419854.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UbiD family decarboxylase"
                     /protein_id="HFG9696931.1"
                     /translation="MNFRDLFEKAVDFIDEKRKSIVAISLSTLGVIALIIVFFLSSNE
                     FSVGNEANELLKIIEKRQYSIAVDYYTSIEKKFSDSKMERFNKSVSKKINKLLLNSGD
                     KYLDGDISQESFIGLINTVKELNKISIDVDDLLAQADRVREMYKEENTTYDIAINYIS
                     TVSILNGMGSNLDVYKQNIETIKESRDVYDSAVKDQKAYKYYEAIEKYNKVLKEDEKY
                     YSMAQNGKEQCIEEMYDYYISRAEEANTSGDYERALQYIEYLKDDYSDDEKVQSLEKK
                     YKKNLSLYTLTSDDIINVIAKKSGKDKANLSINSLPQMIKNNKYYYAEVYEYDKLINE
                     VLVSAKTKDLYSYKDGKKDYKVDYGDGYFRILEDGSYQFGITKDKAKFVLTNTLDEKE
                     NKYKKIEILDIEKADRYVKSKKSLEELFGKYKNIYYYAVVNKGLFRGKEVYAINIYNE
                     KIYAISENGLNEY"
     gene            14733..16202
                     /locus_tag="ACGI5H_001219"
     CDS             14733..16202
                     /locus_tag="ACGI5H_001219"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438615.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VanW family protein"
                     /protein_id="HFG9696932.1"
                     /translation="MSNVNKKLVIAIGAVALVVIIFIGIMCMQFKGEKIAKNTYVNGV
                     NIGKLTKSQAKQELAKKYKLENVDFNYNDKSWKVKSKDLNLSTDLDKTVENAYNLNRK
                     SAFFGNLSKTISANFGKKSNLVVAINYDKNKLKAEMEKIAKEIDVDVKDATLDISGEK
                     VKVIPDSDGLKMDISKSMENFDNQTKKGNYKNELVVKATPAKVKKEQLANIDTNLGTY
                     STTFKTSQINRSINIKLATDNISNVLLMPGETFSFNKHTGKRSKENGYKSAPVIMEGE
                     MEEDYGGGVCQVSSTLYNSVLYAGLEIVNVKNHTIPSSYVPKGRDATVADSGIDFLFK
                     NNLKHPVYIKNYVSGNQIVCNIYGSAEDKQNITISTKLDGVSQTTMKRVNDPTMPKGK
                     EKVDKSGRNAYSVSTYRTFNDANGKKIKTEKIANSYYPKKEGIILVGTMEPKPEEKPN
                     TDENKNNQNTNNQNPNNQQKPETPPTDNKPNETQPQPQA"
     gene            16267..16860
                     /locus_tag="ACGI5H_001220"
     CDS             16267..16860
                     /locus_tag="ACGI5H_001220"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419857.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0043565 - sequence-specific DNA binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HFG9696933.1"
                     /translation="MNLNNITNYVQSICENISNVLDVDVTLVTKDLTRIAGTGIFRGK
                     IGETISEKSVYSLVLKDGKSYVINKEIEENCNKCANRENCKELADICTPVKMGEHILG
                     ILGIAAFNEEQKEKILSKDKELTAFVRSMSDLISFKLDELYKQEVKTIDDLEREAIEN
                     AIKKYGSNTEGMKKVAEALNIGIATLYRKVKKFNIKS"
     gene            16991..18388
                     /locus_tag="ACGI5H_001221"
     CDS             16991..18388
                     /locus_tag="ACGI5H_001221"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005515 - protein binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tetratricopeptide repeat protein"
                     /protein_id="HFG9696934.1"
                     /translation="MEVSIILVKDIKQDIESMPRKILDISLIEDNKSDLTFFNIEEED
                     GDETLKALKQSYVTTNYKEETLLNLQGALNSKSDTTSKELKLESYKRYNNALDLAYKN
                     YITSAINMVNKALEINPKDIDILNLRGLLKLLKCDFAKSFESFYTALCYENNHISRKY
                     VNLISSEDFKTFLGRYNHSIRFINEELNYESIHILENIIEEEPELIEPYVILSLLYDK
                     LGNVKKREGYLDKLKELDKDNPVFEKNEEEKEDTSKKEEIKKVKRKKSILPYIIVGCV
                     LIGMGIYLIQSKKRIENLNNQISSKEEKLSETDKKLGETSKKLEKTNKELNEVKNKEP
                     EREITVADEEDLYYQALNLKKNKEYEKAIDNFKSVVSSGKTKKYISESIYQLAITNKL
                     LGNKDEAIKYYKKYINTYTKNDQYYDDSYYELGMLYYDNGDLKNAQQTFYSLRSEVPD
                     SMYNNSKIKEILSEK"
     gene            18570..18941
                     /locus_tag="ACGI5H_001222"
     CDS             18570..18941
                     /locus_tag="ACGI5H_001222"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419862.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CidA/LrgA family protein"
                     /protein_id="HFG9696935.1"
                     /translation="MKVFNQLVIILSIWVIGEYISSFIQGIILIPGSIVGMLLLFLLL
                     QFKVLDLSSIENVSGFFLDNMAIFFIPAGVSLIKSLDLIRENVLVLLLVICLSTLIVM
                     YTTGIIVEKMIKKKEEGQKNV"
     gene            18934..19623
                     /locus_tag="ACGI5H_001223"
     CDS             18934..19623
                     /locus_tag="ACGI5H_001223"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438619.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LrgB family protein"
                     /protein_id="HFG9696936.1"
                     /translation="MYNVLQTPVFGIIVTIVFFNLGRYIQRKTSNPICNPLLIAIVGI
                     ILFLSISKIPYENYKIGADSLNFFLGPVTVVLAVPLYKQFELFKKHMFEIIVGIGCGI
                     VISFVSVLIIGKIANSDVSIINSLIPKSITTPMGISLANSLNGVESITVVAIIFTGIF
                     GGMVASTVFKLGNINHPVAKGIALGTSAHALGTTKAFELGEIEGAMSGVSIGVSGTIT
                     VILIPIIMNFI"
     gene            20143..21009
                     /locus_tag="ACGI5H_001224"
     CDS             20143..21009
                     /locus_tag="ACGI5H_001224"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429405.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HFG9696937.1"
                     /translation="MSEVKNTLQKHPVLRYSTMLFGMLMTSIGINGFLRPAHLLSGGA
                     TGIATSINYLTNINVGLLTFLINIPIFILGFIYLEKEFCISSLVNMIVFSLLLGATQE
                     ISNIIPIHDILLQSVYGGILSGLGVGVVFRTRSSQGGTDIIAAILKIKKNIEMKDTAL
                     AINGLIVLTGSFLFGLDLALYTLIGLFLNAYSMSFIKDAMNYQKSVMVMSNEVDLIAE
                     DIMKSLVRGVTFLDAEGAYTHQKKKIIYTIVSSNEIPKIKDIALKYDKKAFISVNDVT
                     EVKGRGFKAKDL"
     gene            21251..22060
                     /locus_tag="ACGI5H_001225"
     CDS             21251..22060
                     /locus_tag="ACGI5H_001225"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889246.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MORN repeat-containing protein"
                     /protein_id="HFG9696938.1"
                     /translation="MNLSKEYVNLYDNYLKYINEVNKEIRSIKNMKKRVLKRGDFAPE
                     NEVLELEGKTIRDIDDVDTKKPKNKIYKFSNGDVYVGKFLEGKMEGKGSYTFFVDEGT
                     VMEYIGEFKEDKKNGKGNFIFSNGNEYIGYFEEDMMSGIGNMLYSSKDEYIGTWKNGK
                     KDGKGIYKWSDGCIYAGEFKGGKMEGYGICYNSKGEVLYEGEWKNNLIHGKGTYIWEK
                     GKKYIGEFMHGKKHGQGTFYLNNELVYEGTWKFDKPSIFDRTLDEIFSLRL"
     gene            22204..23268
                     /locus_tag="ACGI5H_001226"
     CDS             22204..23268
                     /locus_tag="ACGI5H_001226"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728685.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CAP domain-containing protein"
                     /protein_id="HFG9696939.1"
                     /translation="MKRLIALVLVVLIVLFYSPELLKEGYDLKEKFFQSEIWNEFLDK
                     ININDNSKKDKKEKSQNLQSNNTEGENLGESDIKNFEKISLGDNLSYVLSSIGKPGRI
                     DISEYGFDWYVYNQYGKEFAMVGLENDEVVALYSNSINSCENQDIKLNQDRQTVRTKI
                     TPLKYKRKGNTRYIINSENQYDIISKEGKYITIFYDIHEENRVCSYLIIDKSTEDEFK
                     NLYPDDSEELKKCFELEVIDLVNSVRNQRGLNSLRYSEQATLSSRKHSEDMRDNNFFD
                     HVNKKNETPFDRMKREGIVYTSAGENIAAGQINAIYAHEAWMNSEGHRKNILGNYNNI
                     GVGVIFGGSYKTYYTQNFYK"
     gene            23296..24015
                     /locus_tag="ACGI5H_001227"
     CDS             23296..24015
                     /locus_tag="ACGI5H_001227"
                     /EC_number="3.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419871.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide deacetylase family protein"
                     /protein_id="HFG9696940.1"
                     /translation="MTSWKKKTVYKCLIAVVLFCGIVLISNFSKVSALMMDTNGNVLI
                     KHGSREKKLIAITFDDGPHPKETSQVLDVLKKYNVKATFFIAGKHAKWYKEPLVRASK
                     EGHEIGNHTFNHPDISNLSSSQIEEEIVKCEDILKEVTGKKPTLFRPPFGSYREKELI
                     EIAKKHDYKVVLWTGVDVKDWKNPGANSIADKIINKVQNGDIILLHDYATNDTVEALD
                     MFIPKMIEKGFKFVTVSELIK"
     gene            24039..24623
                     /locus_tag="ACGI5H_001228"
     CDS             24039..24623
                     /locus_tag="ACGI5H_001228"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419873.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminodeoxychorismate/anthranilate synthase
                     component II"
                     /protein_id="HFG9696941.1"
                     /translation="MILMIDNYDSFVYNLVQYIEELGETVVVKRNNEIKISDIEELNP
                     EVIVLSPGPCSPKEAGICIDIVEHFKGKKPILGICLGHQTIGHVFGGDIIKAQQPVHG
                     KVYSINHTNKGVFRGLKNPLNVTRYHSLIVDSNTVPKELEITAITDKGEIMGIRHKKY
                     LIEGVQFHPEAILSEYGHEMLKNFITEARERVHM"
     gene            24625..25974
                     /gene="pabB"
                     /locus_tag="ACGI5H_001229"
     CDS             24625..25974
                     /gene="pabB"
                     /locus_tag="ACGI5H_001229"
                     /EC_number="2.6.1.85"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889251.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0046820 - 4-amino-4-deoxychorismate
                     synthase activity [Evidence IEA];
                     GO_process: GO:0008153 - para-aminobenzoic acid
                     biosynthetic process [Evidence IEA];
                     GO_process: GO:0009396 - folic acid-containing compound
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="aminodeoxychorismate synthase component I"
                     /protein_id="HFG9696942.1"
                     /translation="MIREINTKLNSFEIFTIFRNEHDSFILDSAMDKEKLGRYSFISS
                     QPFKVLKYKDTDENPLEVLKEELHKYRVVNDTNLPFVGGAVGYLSYDLGNYIENLPRT
                     AVDDIEMPDMYFGFYNHVIVIDHLVQKTYIATPNIDIELEEKIIDDIEQRILKEEKKG
                     IDSICYEEKEVTPIRLKSNFTKEEFKNAVQSVREYIRQGDIYQANLTQRFSGETELTS
                     FELYRDLRRFSPAPFGAFLNFEDAHILSNSPERFIRCVNKRIETRPIKGTRPRGKDKE
                     EDLRLQQELRNSEKDRAELLMIVDLERNDIGRISKTGSVKVPELFVIEPYANVNHLVS
                     TVVGELKDDKDATDVIKATFPGGSITGAPKIRAMEIIDELEPTQRNVYTGSIGYIGFN
                     GDMDFNIAIRTIIKNDKKVYFQVGGGMTWDSDPDEEYQETLDKAKSIMKALRGYYEE"
     gene            25964..26707
                     /locus_tag="ACGI5H_001230"
     CDS             25964..26707
                     /locus_tag="ACGI5H_001230"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728682.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminotransferase class IV"
                     /protein_id="HFG9696943.1"
                     /translation="MKNNVGFDSSLSKFGIGLFETIRVKNGIAVDLDIHIERMLSSIN
                     CLDLDIKYKKDFLINEIVTYIKKENVINKALRITVFDEGYNISIRDIPYNQETYEKGF
                     KLAISPIVRGNSLIHRHKTTNYFENIYTKNIANKTGYNDGIFLNSEGVILECSMSNIF
                     FVKGERVYTPSDRLPILNGIIKKRIIEICDELHIELIENEINISEISSFDFVFVTNSL
                     MGAIKVTEIDKIKFNKENVVFDKIVKLLE"
     gene            26741..27442
                     /locus_tag="ACGI5H_001231"
     CDS             26741..27442
                     /locus_tag="ACGI5H_001231"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728681.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9696944.1"
                     /translation="MIGCIYEVYNEEITKIIENQNTLAVYLVGSSKDVDFTLYDVEIN
                     DIDVFVFVKEGEKQERILFKKKGIEFDVNYFSKDGVKKLLSNREYFFVKEMKDAKVLF
                     DRENISHIIKDISRNIYLEGPSKMSLEEKSFIKQDIGAKISNLKNKEKFDVFEYHFLT
                     NLYLKDIIIGYFNINDKWVPKDKKLLKVLKKENNELFELVSKVSENYDYQRLLDVYNY
                     IFKEIETKEVIKLIF"
     gene            27468..28040
                     /gene="folE"
                     /locus_tag="ACGI5H_001232"
     CDS             27468..28040
                     /gene="folE"
                     /locus_tag="ACGI5H_001232"
                     /EC_number="3.5.4.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007287029.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003934 - GTP cyclohydrolase I activity
                     [Evidence IEA];
                     GO_process: GO:0046654 - tetrahydrofolate biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GTP cyclohydrolase I FolE"
                     /protein_id="HFG9696945.1"
                     /translation="MNKVDKEKIQHAVREILEAIGEDPDREGLIETPNRVARMYEEIF
                     SGLSEEPRDHLKVLFADEKHEELVLVKDIPFYSCCEHHLVPFFGKAHIAYLPKGGRLT
                     GLSKLARVIDTLAKRPQLQERITKNAADIIMEELQPYGVLVVVEAEHMCMTMRGVKKP
                     GSKTVTSAVRGIFEKDIASRAEAMSLITMK"
     gene            28104..28895
                     /gene="folP"
                     /locus_tag="ACGI5H_001233"
     CDS             28104..28895
                     /gene="folP"
                     /locus_tag="ACGI5H_001233"
                     /EC_number="2.5.1.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004156 - dihydropteroate synthase
                     activity [Evidence IEA];
                     GO_process: GO:0009396 - folic acid-containing compound
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="dihydropteroate synthase"
                     /protein_id="HFG9696946.1"
                     /translation="MFDYGKRTYIMGILNVTPDSFSDGGDFNNLDIAIQHAKDMVDQG
                     ADIIDLGGESTRPGHSYVDSDEELRRVIPVIKKLKQELDIPISIDTYKADVAEEALKL
                     GVTMVNDVWGLRKDKNMASVIGKYDAEVCIMHNQDGTNYDKDIMESIKDFFKVSIEMA
                     MSCGVKKEKIVLDPGVGFGKDFEQNIEVLRRLNELKDLGYPILLGTSRKSVIGKVLPV
                     EPKKRLEGTIATTVLGIRDGVDIVRVHDVYENLMAARMTDAIYRK"
     gene            28906..29271
                     /gene="folB"
                     /locus_tag="ACGI5H_001234"
     CDS             28906..29271
                     /gene="folB"
                     /locus_tag="ACGI5H_001234"
                     /EC_number="4.1.2.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889257.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004150 - dihydroneopterin aldolase
                     activity [Evidence IEA];
                     GO_process: GO:0006760 - folic acid-containing compound
                     metabolic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroneopterin aldolase"
                     /protein_id="HFG9696947.1"
                     /translation="MDKILLSNLGFYGYHGVLKEENFLGQKFFVDMELYIDSREAGLS
                     DDINKSVSYAEVYNVVKDITENKQFNLLEALAENIAEEVLNKFILINGVMVRVRKPEA
                     PVNGIYDYFGVEIRRTRDE"
     gene            29264..29770
                     /gene="folK"
                     /locus_tag="ACGI5H_001235"
     CDS             29264..29770
                     /gene="folK"
                     /locus_tag="ACGI5H_001235"
                     /EC_number="2.7.6.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003848 -
                     2-amino-4-hydroxy-6-hydroxymethyldihydropteridine
                     diphosphokinase activity [Evidence IEA];
                     GO_process: GO:0009396 - folic acid-containing compound
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="2-amino-4-hydroxy-6-
                     hydroxymethyldihydropteridine diphosphokinase"
                     /protein_id="HFG9696948.1"
                     /translation="MNKAYLGIGTNMGDRFDNLSRACELLKNSDSIYKVKESSLYETK
                     PWGYTEQADFLNMCVEIETEFEPYELLEYCQEIERELHRERIVHWGPRTIDVDVLFFN
                     DVVSTDERLTIPHPRIQDRAFVLIPLMDLNEELIINEKTIKEHLNLLSAEEREEVKEL
                     VGYERKPI"
     gene            29751..30536
                     /gene="aroF"
                     /locus_tag="ACGI5H_001236"
     CDS             29751..30536
                     /gene="aroF"
                     /locus_tag="ACGI5H_001236"
                     /EC_number="2.5.1.54"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419887.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003849 - 3-deoxy-7-phosphoheptulonate
                     synthase activity [Evidence IEA];
                     GO_process: GO:0009423 - chorismate biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="3-deoxy-7-phosphoheptulonate synthase"
                     /protein_id="HFG9696949.1"
                     /translation="MKENLFNNNSKIEINTNNKKITVKKDKLIIAGPCAIESYEQLLE
                     TAKFVKSQGANILRGGAYKPRTSPNSFQGLKKEGLEILKAVKDEVGMAVITELMDVRD
                     MDELYSISDIIQIGSRNMQNFTLLSEVGKQNKPVMLKRGIASTITEWIGASEYIAIEG
                     NSNIIMCERGIRTYNDYTRNTLDLAAVPIIQKETGLPVVVDPSHATGVRYLVKPMSLA
                     SFACGADGIMVEVHPDPENALSDGAQSLCFNEFEDLMKSINNY"
     gene            30791..32581
                     /gene="dnaG"
                     /locus_tag="ACGI5H_001237"
     CDS             30791..32581
                     /gene="dnaG"
                     /locus_tag="ACGI5H_001237"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893065.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003896 - DNA primase activity [Evidence
                     IEA];
                     GO_process: GO:0006269 - DNA replication, synthesis of
                     primer [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA primase"
                     /protein_id="HFG9696950.1"
                     /translation="MNDIKDIIEEIKARCDIASIISEYMNIKQSGANYKGLCPFHGEK
                     TPSFYINTSKQIYKCFGCGEGGDVINFVMKMENLDFMDAVKILANKCGIEINTNMNEE
                     TRIKIEKSKKFQDIHTEAARFYLSNLLGSKNLGYEYLRIRGLDDKIIKKFGLGFSLDS
                     WNSLMNTLISKGYKKQDLLECGLIAKNRDGTNCYDKFRNRVMFPIFDYRGNIIGFGGR
                     VLDDSLPKYLNSPDTLIFNKKQNLYGLNFARKNLESKTIVLVEGYMDLISLYQYGIKN
                     VVATLGTALTEQQGILIKRYADTAIISYDSDEAGIKATLRAIDILTKLGINVKVLDLK
                     DAKDPDEFVRKYGLSDYKKAMDVSTHYIKYKIDHLKKEFNIQKDEERVKFAKEASKII
                     KQLTSPVEIDFYTKYLSNQIDINVESIKREVYGKNYNKPYNNKNQKKIEEKVIEKVEV
                     RQDGKQLVEETLIKIMLEDKKIREIALLKVEESDFLLKESKEILNYMIKNQELDKITI
                     DKLKSLNISEEYLKELNSISLNSINLENTKEIEGIITNIRKNSLEEQINSLLREQQEL
                     ENNNDMKEVDGRVMEIALKIVEINKILKSL"
     gene            32599..33765
                     /gene="rpoD"
                     /locus_tag="ACGI5H_001238"
     CDS             32599..33765
                     /gene="rpoD"
                     /locus_tag="ACGI5H_001238"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429425.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0016987 - sigma factor activity [Evidence
                     IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="RNA polymerase sigma factor RpoD"
                     /protein_id="HFG9696951.1"
                     /translation="MENKSNKKELKKVTAKTLIEKGKKQGSLTLAEIMEAFSETELDK
                     DQVENLYETLGNLGIEITETKNYKADIDFSVADDDLSIGHLDEDAEAISHDDSSAIEI
                     ETVDLSLPKGISIDDPVRMYLKEIGKIPLLKPHEEVEFARRMHEGDEIAKQRLVEANL
                     RLVVSIAKRYVGRGMLFLDLIQEGNLGLIKAVEKFDYTKGYKFSTYATWWIRQAITRA
                     IADQARTIRIPVHMVETINKLIRVSRQLLQELGRDPKPEEIAKEMEMTEDKVREIMKI
                     AQDPVSLETPIGEEEDSHLGDFIPDDDAPAPAEAAAYSLLKEQIEDVLGSLNDREQKV
                     LKLRFGLEDGRARTLEEVGKEFDVTRERIRQIEAKALRKLRHPSRSKKLRDYLD"
     gene            33930..34619
                     /locus_tag="ACGI5H_001239"
     CDS             33930..34619
                     /locus_tag="ACGI5H_001239"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419893.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (adenine(22)-N(1))-methyltransferase TrmK"
                     /protein_id="HFG9696952.1"
                     /translation="MKLTDRLLKIASLVSDGKKIADIGTDHGYIPVYLLKEGKVPFAV
                     LADVNKGPLDNAHKEVIQNNLLDKVDLRLGSGIEILEIGEVEEVIIAGMGGILISELL
                     EAKKEVAHNVEKLILQPMQAQEELRYYLLNNGYEILEEVLVREDFRIYEIIVAKYTGK
                     NTIIEDEIYYEVGIKLLENKDSLFNDFIEKKIKTYSSIVNKLEGKNGEAIDKKRKESE
                     VAIKKLENLIK"
     gene            34633..35730
                     /locus_tag="ACGI5H_001240"
     CDS             34633..35730
                     /locus_tag="ACGI5H_001240"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896378.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0051540 - metal cluster binding [Evidence
                     IEA];
                     GO_process: GO:0008150 - biological_process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Nif3-like dinuclear metal center hexameric
                     protein"
                     /protein_id="HFG9696953.1"
                     /translation="MLLKSLTRKIEKKYPLNLAEDWDNVGLIVGDFDMDVKKVLVSLE
                     ANEDVIDEAISKNIDLIVTHHPFIFGKINKINSGDLKGRLIQKLIKNDISLYSMHTNF
                     DIAFDGLNDYFMEIMEFGNSKVLDITKSENLYKLAVYVPHNYSDELRKVLSNSGAGHI
                     GNYSDCTFSTEGEGQFKPLEGSNPFLGSVNDIETVNEVKIETVVPQKLLGGVISSMLD
                     AHPYEEVAYDLYKLENKGEIFGLGRISKLDKSMTLESLSRKIKEKLNMKHIRVVGNLS
                     TDITKVAVVTGAGSEFVKKAKRQGAEVLITGDVKYHEAQDALDIGMCIVDCGHFDTED
                     IFKNVMKRFLDEFSEIEVIKSNVYLNPFSTI"
     gene            35793..36365
                     /locus_tag="ACGI5H_001241"
     CDS             35793..36365
                     /locus_tag="ACGI5H_001241"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896380.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0009055 - electron transfer activity
                     [Evidence IEA];
                     GO_function: GO:0010181 - FMN binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="flavodoxin family protein"
                     /protein_id="HFG9696954.1"
                     /translation="MKVAVIFHSVCGSTYLLAREYKEALEEMNIEVDIFRVSDEVAKT
                     LPQYYLINSKEYKDEFESINVIKSGKEILDYDAIFMGSPTYYGNVSGPMKMFMDSFSD
                     IWVGAPLSGKIFGCFATAGSQHGGGELALQAMNIFAQHMGMTLLSVPCSVRGGYPAYG
                     ILHIAGDNSDIRPNDDAKIGIRDYLKRLNI"
     gene            complement(36425..36892)
                     /locus_tag="ACGI5H_001242"
     CDS             complement(36425..36892)
                     /locus_tag="ACGI5H_001242"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429434.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxamine 5'-phosphate oxidase family
                     protein"
                     /protein_id="HFG9696955.1"
                     /translation="MFKEMRLKKREMTKEDTVEVLKNGEFGTFSTISENGYPYGVAVN
                     YVYFNDSIYFHCARNGHKLDNISKNNKVSFLVVANESVIPDKFSTTYSSAIVFGKACT
                     VENEEKKNALVEIIKKYSKGFFEEGMKYIEKDMNLTTVVKIEIDHISGKASRL"
     gene            complement(37278..37754)
                     /locus_tag="ACGI5H_001243"
     CDS             complement(37278..37754)
                     /locus_tag="ACGI5H_001243"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896384.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HD domain-containing protein"
                     /protein_id="HFG9696956.1"
                     /translation="MLSKAEIKYFNECASEILSSEKVQLMRTFPHHGNVSCLEHSLSV
                     AYYSYLLCKKLHLSVDIQSVIRGALLHDFFLYDWHYKGDRKGLHGFTHPREALKNATL
                     FFQINEKETDIILKHMWPLTVKPPRYKEAFIVCLLDKFCCLVETLKIHSLLSPYHV"
     gene            complement(37874..38965)
                     /locus_tag="ACGI5H_001244"
     CDS             complement(37874..38965)
                     /locus_tag="ACGI5H_001244"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF5808 domain-containing protein"
                     /protein_id="HFG9696957.1"
                     /translation="MSKIECLFTIFPVLILMYATFYFIPYFVGKKHIYGVSIDQEHKN
                     YNYFIKLDKEFKKLLSLGFIIDFILVFILVFTFNKLELSYFIGIIGFLLYESILYIHT
                     HKKAKKLKSEIYAKLGHIDIDSKLIVDMDFINKKNKIIKKFKIIYLIPILFTLGMSIF
                     IAFNYNQLPDSIATHWNINGSPDVFIDKSFLNVFKLIGTDFCLMVLLYITSIGSIKSR
                     IKIDTNRIEESRVENIKYLNKIGYLFLILMIIMTTQFFTTLLSIKTKLLTAMNITTLL
                     VIIYLIATYINSPNLKFNSSYSPEEDEKYWIAGIMYNNPNDPSLMVNKRFGIGWTINF
                     GNPLGKILYIAIALLLIFSLFSLIKSLLL"
     gene            complement(38958..39347)
                     /locus_tag="ACGI5H_001245"
     CDS             complement(38958..39347)
                     /locus_tag="ACGI5H_001245"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429441.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HFG9696958.1"
                     /translation="MVLNLDFNSDKSIYVQIKEEITKAIASGELKINESLPSVRSMAE
                     NIGVNLHTVNKSYNELKEEGFLNIDRRKGAIVAQLPMKIDNTTRQKNKLDLELLVAKS
                     YLSGISKEEFLSLSSSLFDKYEVKYYE"
     gene            39539..39985
                     /locus_tag="ACGI5H_001246"
     CDS             39539..39985
                     /locus_tag="ACGI5H_001246"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861223.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9696959.1"
                     /translation="MLTYLMKRQMHKKDDGMSKPMMITGAVITGVGAYAVYKMVKSHK
                     SNSQMVNTNYYGNSDYDDYKYDEFDYDCDCRDTKQDYEYEELKKKVKEFNSRRINCEN
                     CPHVSQEEMMQYVNSVKDVKEELDLHEDAKKDNIYKEDEYKKYEEE"
     gene            40270..40974
                     /locus_tag="ACGI5H_001247"
     CDS             40270..40974
                     /locus_tag="ACGI5H_001247"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861224.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000156 - phosphorelay response regulator
                     activity [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HFG9696960.1"
                     /translation="MLKLLIVEDDSTISFGIKYALEQEGFSIDISKDLSSGKEMISSN
                     EYSMILLDVTLPDGTGYELCQYIRGFSQVPIIFLTACDEEVNIVMGLDIGGDDYITKP
                     FRIRELISRIKAVLRRKGNTSEENKKILKFGDLSIYTLEARVYKNDKEIFLTSVEYKL
                     LLILIQNKNTVLSRTQILEKLWDVTYDFVNDNTLTVYIKRLREKIGDDLCEPIYIETV
                     RGIGYKWIGSENSVSI"
     gene            40952..42205
                     /locus_tag="ACGI5H_001248"
     CDS             40952..42205
                     /locus_tag="ACGI5H_001248"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728679.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing sensor histidine kinase"
                     /protein_id="HFG9696961.1"
                     /translation="MKIVFLYNPEVKKFLSKYVTLMFIVIIISIGFSIINVSLTKEMV
                     VRNNQAIIGTLSSKYPNLESQIVDIITQGKSMENIDYGQKILIKYNYDKSIRINSEPI
                     ISKLVLETIKINIILVCIIFILIFVLIVRYFTSIYNDLSDMTKYVYYSSEGKPFDMKN
                     KNQEGQIGLLKTELLKMTTILNEKVELLKREKIFLNNTISDISHQLKTPMTSLIMLND
                     LLYNDVPYEVKIDFLNKIKNQLNRMDWLIKSMLKLSKVEAKVINFKKDKVKFSELIHR
                     AMLSMKIPMEIKNQKLTIEGNDNVSYIGDIDWSVEALVNIIKNCVEHTPEFGNIIITY
                     KENPLFSELIIKDEGEGIDKKDIPHVFKRFYRGRSSSKEDSVGIGLAMSKSIIESQNG
                     DIYVNSEKGKGTEFHIIFHKMYDSD"
     gene            42285..42962
                     /locus_tag="ACGI5H_001249"
     CDS             42285..42962
                     /locus_tag="ACGI5H_001249"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438655.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HFG9696962.1"
                     /translation="MEILRVENLTKSYGKNETKVDAIKNVSLSVEKGTFIAITGPSGS
                     GKSTLLHLLGGVDRPTSGKVYINDVDIYNLKTKDLAIFRRRNIGLIYQFYNLIPVLNV
                     KENILLPAELDNRDIDREYFDDLMKTLGLIDREKHLPNQVSGGQQQRTSIGRALINRP
                     SIILADEPTGNLDSKNSKEILELLKLSVKKYNQTLIMITHDKNMALQADRIISIEDGI
                     IKSDEVM"
     gene            42963..45524
                     /locus_tag="ACGI5H_001250"
     CDS             42963..45524
                     /locus_tag="ACGI5H_001250"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419912.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HFG9696963.1"
                     /translation="MNLYTSLTIRYLKQNKRRTIVTIIGIILSTALICGIGNIFESFM
                     DYQMRETIKNDGSFHVTFYDVNRKNVEYVTKSAEIEKHAFTKQLGYSKLENSENAILS
                     IKQYDKNAINGYKVSIKEGRFPAKEGEIVLSESIINLIDDKLKIGDKITLKVGDMFDS
                     SKKKIDSMTFHEGDYIANEKDRTFKVVGIIEKPGFERYNGIATAIAYFNPMNNYNDTI
                     NVSVAVKNPKDVYKISNKISKNIYSNKDKEAVSDMIKYNEHLLRLQGASKYSNINSSI
                     KSIIIAVTILVIVCTIATVYNSFSISINERKKQFGILNSIGATSSQIKRLVFIEGIII
                     SLIGIPIGLISGTVAIDLLFKIINKYFTESVVTKMSLQIVYNPIIIIVSIIIVLLTIF
                     ISILLPAISASNISPLNVIKNTGEYKVGKIKSSRLIKMIFKTEGVLAYKNIRRNRKKF
                     IITLFSLMVSIIIFISFSGFTLLLLRGEEIRNSQRKYDLYLTAKNTARSVEDTISELE
                     DIDGIKNFELATGQYVSIRVSENKINKSKEDLIRKYYQKYKIGDSYEYDFSNNELIFP
                     GDFAVKNKINNLVQGSFNKERAIEENGVILVRKSAIEENGKKGVVELTNYKVGDTVNC
                     EYLDENALSKKVKVKILAITDEERLGLGYQNMGLQFITYDEVAKNLNLKLSKSLIFID
                     SGGSIKTKKEIEALANKNNFNFYDESASNESEKQDLKVIKIFVYGFIVVISLVSVTNI
                     LNTVSTSINLRKRELAVIQSIGVTPKGFRKMIYLESFIYGILSLLFGIPISIGIILIM
                     NKLISGVIEFSPIIPWTAIVICIVSVFIITFIAGYIPMSKLNKENIIDNIRRESI"
     gene            45745..47019
                     /locus_tag="ACGI5H_001251"
     CDS             45745..47019
                     /locus_tag="ACGI5H_001251"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419914.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0051536 - iron-sulfur cluster binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="4Fe-4S dicluster-binding protein"
                     /protein_id="HFG9696964.1"
                     /translation="MITISHITAKNMYKSLEERINKFPQGAPPSDTLYKILNVLYTEQ
                     EAKLVAQLPIKPFRVKTAAKIWSVSESEAYRVLDKLASKALILDIEDNKGKKYIMPPP
                     MAGFFEFAMMRTRHDIDQKLLAELYYQYMNVEEDFIKDLFYSTETKLGRVYVQEEVLT
                     NDNEVSILDYERATHIIDESTHIGISMCYCRHRMQHVGKACDAPMDICMTFDNVANSL
                     INNKFARRVDKIECKELLHQAYEHNLVQCGENVRKGVTFICNCCGCCCEAMVAAKRFG
                     NLHPVQTTSFIPNINHENCVKCGKCITACPIDAISKVKEDGKEYIKIDEDRCLGCGVC
                     VRNCHKNSIMLLKRDEKIITPANSVHRAVLMAIEKGQLQNLIFDNNALASHRAMGAIL
                     SAILKLEPAKKILASKQLKSVYLDKLLSMNDK"
     gene            complement(47180..50221)
                     /locus_tag="ACGI5H_001252"
     CDS             complement(47180..50221)
                     /locus_tag="ACGI5H_001252"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419918.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall-binding protein Cwp20"
                     /protein_id="HFG9696965.1"
                     /translation="MFKQRLSKLLSSTLVLSMLFTAAPNITFADNTKDNSEKYQSSDI
                     ELHDYSKNAESYTKTKALAKEKIQTLLSKYGAVSAQYALIDNGKIEISGNGGVYSKQD
                     NKNLNKDNMYSIASISKMFTTTAVMKLVDDGKLNLDTPVVKYIPEFKMADDRYKEITP
                     RMLLNHSSGLMGSSFKNTILLADNDSYGHDNFLKELQKQRLKAKPGAFSVYCNDGFTL
                     AEILVERVSGMSFTNFLDKYINNPLNLQNTKTTENSFDSSKLAKAYVPYWEDAVPQDN
                     LNAIGAGGLYSSAENLCTFAQTFMKNSNGILSPASVKAMENKEYLNGLWPEGEDSILG
                     YGLGWDCVNTYPFNQYNLKALTKGGDSLLFHSNLIVLPDENMAVAVLSSGGSSQLNEI
                     IGQEILLSALKEKGKIKEIKPDKTFSKPQQVKMPSSLKENSGLYASSNMIKVDVNDNG
                     TLTVSSPYIENGPEDKYVYIGQDRFVSEKGNSCLKFVKEKNNITYLNMSSYDDVPGLG
                     QTASLYYVAQKIDDNNISNSVKEAWKKRNGKDYYLVDEKYTSQSYMFGSVKATLALSD
                     ETPGYIVNTKIMDENNSNAFIEIPGVIGRDLSDIKLHKENGTEYLSFGTLTYVSEDSI
                     TNLPAEKSFTCELESNGYAKWYKIGDDIANKKIEVNLPQNSAFAVYDDKGVPVNYSLV
                     TKNNRVRLPKGGVIVFLGSPNARFEVTYQDEVNASALTGTDRYETSIKISQAGWENAE
                     NAVLINDSAIADALAATPFAYKKNAPILLTGSSQINEKTLAELKRLKVKNVYVVGGEA
                     SINEKSLDTIKSNNISVSRISGSDRYQTSMNIAKELNNISNISKISVVNGEKGLADAV
                     SIGAVSAQNDMPIILTNENSNITEINNLFKNKKIDKSYVIGGEYTVSKNIESKLQNPQ
                     RISGSTRNETNAKVIKEFYKDSKIDNLYVAKNGMNKQDDLIDGLSVGVLAGKTKSPVM
                     LVGNSLDYNQKELFKTMRFKSVTQIGGNGNENSFKQIKEIA"
     gene            50427..50726
                     /locus_tag="ACGI5H_001253"
     CDS             50427..50726
                     /locus_tag="ACGI5H_001253"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429454.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhodanese-like domain-containing protein"
                     /protein_id="HFG9696966.1"
                     /translation="MYKNINKKQLKEMMKNEKDVLLLDVRTKDEFKEYKIENAINISL
                     QELINNIDEIYDYKDKKVVVYCRSGHRSVTACNLLAEEGFEHLYNLNSGIIDYMS"
     gene            complement(50965..53193)
                     /locus_tag="ACGI5H_001254"
     CDS             complement(50965..53193)
                     /locus_tag="ACGI5H_001254"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438668.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YhgE/Pip family protein"
                     /protein_id="HFG9696967.1"
                     /translation="MRHLKKTNSLKEILNWNNIKNLRPSKGLKNILEIFKSDLKDIRG
                     NYAVLVIVLGLAFLPSLYAWFNIKASWDPYGSTANMLVAVTNEDKGNEIAGQKINVGD
                     QLIEQLKDNKSLGWQFVDEKTALEGVKKGTYYASLKIPKNFTKDLTSLITDDVKKGEI
                     IYTVNEKINAVAPKITDKGASTIQLQVNQTIVKTVSEIVLGISNGVGAGIEHSLPKLT
                     KVENSLIDLQKRFDHINKTVDLASDATSKLSDTVKDIKSDLPTIKKTLNDTKLLSSDL
                     KKFLEDTNDNLDELSPLIKSDLNLMVDLSSSASSLTLNLIDAVNSGSEDVPKLIDNLS
                     EKLSNLQSLNDTLVDFLTKLNQLTSNNRLDDVIDNLEDSSNKIDSSISTLNDIKNKVI
                     SGQQPSISALNNVLSLSNGIGRINLNILNNFDSKISKPINSIFANSIKVANDIITVLD
                     KAEAKLPKVEEILTTSLKLSGNAQESISLIRERLPLAKGMLDDLIDTLSKISNGEDMK
                     KLVSLLESDILTKSNFLKEPVEVKTEKLYPIENYGSAMTPFYSVLSTWVGILLISALL
                     STSVHGNYKPYEIYFGRGLTFLSIALVQGFIIGTGDILLLGVTAKHPILLIVLLMFTS
                     MVFNFIVYSLVSVFGNVGKAIAIVLLVVQIGSSGGTFPIQVTPTFFQRINPIMPFTYA
                     IGATREAVGGIYAPNLTKDILVLLLFMILSICLNVLLKGPINRVIKPFNDKFGDSNLT
                     GH"
BASE COUNT        21176 a         5745 c         8739 g        17617 t
ORIGIN      
        1 attaggatgt ttattttcct atccttgttt taaagatttt tttagtatat tctaatacta
       61 tagtattata gagtaataat gttgatttaa aataaaaata agatttcgga ggagtttatt
      121 atataaatga aagattacta taaaatagga gagatatcta aaatatatgg aataggtaga
      181 gattcattaa tgtattatga agaaataggc attctaagac cagttagaga tataaatgga
      241 tatagaatgt ataatatatc agatatatgg aaattaaatt taataaaaga atttagaagc
      301 ttgaactttc caatgaagaa aataaaagaa tacctagatg acagaagtat agagtctacg
      361 aaaaatattt taaatgaaga actcgattta attgataaaa aaatagctga atttataagc
      421 cataaggaaa atattataaa aagattgagt tcaattgaaa gtgtaattca aaatacaaaa
      481 atagatgaga tagaggttgt atatatagaa aaaagaaaag ctttagaatt aaatgctgat
      541 ataaagaggg atgaagactt cgatttttta attcaaaaac ttcagaaaga atatgaagat
      601 agatttaata tacttggaaa caacaatatt ggttctgcct tttctactga agcaattaat
      661 aaaggcatat ttaatgagtt taaatctgta ttttgttttc tggaaagtaa tgagaaagta
      721 tataatatag tttttgatga aggatattat gtaactttaa attatactgg gagtaattct
      781 aataataaga tgtatatgga gaaggtgttt aaatttatag aagaaaataa ttataagata
      841 attgctgacc ctatagaaat ctataagata gatatacatg agactggaat tgtagaggag
      901 tttgtaacag aaattcaagt tcctataact aaatatctat atttcaatgg attagatggt
      961 aaatagaatg aaaaaatgtt gatttggcac cgatttgcca ctgtgttata aaatcggtag
     1021 caaattatat tttaaattat aagatagcat gaaaaaataa ttgtttaggg ggttataaat
     1081 gtgaaatgtt ctaattgtgg aagtgtaaat attgaaaagg gaattttaac aactggtggc
     1141 atatatgctg aaactattgg attaaaatat agaggagatg gaaaattaga taaagttata
     1201 aataaaactt ttccagtaca atctactata tattcagatt tatgtttaga ttgtggcgaa
     1261 atagttagaa cctatataaa ggataatact gataggaatt ggtgtaaaga taagaaatag
     1321 aataattttt gaagttgaat tttattaaag atacaagtga aaaagtataa atgggaagaa
     1381 attgttatat ggaagaaaac tttgcatata tggaagatta gttttttaat ataataacat
     1441 ttttaaatgt agataaaact aaaaagggtt ctctagaaaa caatttctat ttaattatac
     1501 ttacttacca ataccatcac ttgatgtaaa caagattcta ctacattttc tccgtactct
     1561 agtataaaat catctagctg tgtatctata aaatcacaat aatcatataa actactaata
     1621 taagcagtta acatgtgtgt acatttatcc atttcatctc taaacatata tattactatc
     1681 cccctaaaaa actttcataa aacaaaaaga acaatatctt tttggcaact ggctgacata
     1741 actcatagtt tattttataa gcgttagtcc ctatagcttt gcgtcactaa atttctctag
     1801 ttttgccgat ttagttttat tctacaacta aaataataca ctaggataag ttattgttca
     1861 acatacttgt cagaaaattg aaatatttaa caatatctta acaatatgaa atctattttt
     1921 cactcaagaa acaaactata tgtatagaat gtttaataaa aattatattt agttttgtat
     1981 tgaagttttt gtattaaaaa gtttagttca caagggttac ttggctagat aatagataaa
     2041 caaaaatatc ttgaaaaaat atatatgaat ggcaaaaaac aagggatgaa ttttatatag
     2101 actcatccct taattattta tatattgacc ttgattaaat atattattat ttttaagctt
     2161 caatttttat attatatttc taaagtttct ataagaggat tatcgctaaa taattttaat
     2221 aaatttgttt ttttatatcc tttaggtaac ttagtatata taactacttc taaccaatcc
     2281 ccatcaaggc gtttaatatt catgtttata atttcaatat tagatttttt aaatttacct
     2341 tcaatatatt ctatggaatc agtgctgtta gaaattttaa gagaaacttg ctctgctgta
     2401 gggagtttca tccatttcct atctctatga agtgttatct gtacaataac aataatgata
     2461 cttgaaacaa taccaactaa gtataatcca gagccaatgg caagacctgt accggctgtt
     2521 gcccatatac cagcagctgt agtaagacca cttactgatt gatttctaat aaatattaat
     2581 ccagcaccta aaaaacctat accactgaca acttgtgctg caacgcgggc tgggtctaga
     2641 ccaatacctg gagtacccac tatatcatta aatccatact tggaaacaat gattataagt
     2701 gctgaagcta atgccactat aaaatgagtg cgtattccag cttcttttag tctattcttt
     2761 ctctcatatc caattaaagc cccacagaaa ccagcagtaa tgattcttgc tatatattca
     2821 aattgaatca atatatgatg gttcatttat ctagcacccc cttctatata atattatata
     2881 tactataata ctacattttt tatgtgaata tagtaaagtt taaaatttat ataatagtta
     2941 tatatgaata taaaatgtat aaacgtatat tatgtatata aaaatgatag aaagcatcta
     3001 attttaaatg attaaagagc aagcttaaat aaatcaaact tgctctttta acatagtgta
     3061 tgtttttatt tgtaatagtt agataaaaat ttatctgtgt tttttacatc tgcaaaactg
     3121 ttctgtagtg atgccatgaa tacttgatgt acagtatttg cattaatttc tatattattc
     3181 caagataaat tcttcgttgt acatgcatcg cttattagag ttatgtcgta tcgaagtttc
     3241 tttgctgttc ttacacttgt atcaatacac atatggctca tcattccaca gattactaga
     3301 ttagtaatat tttttttctc aaggatactt tgcaaatctg tttcaaagaa actatctggt
     3361 gtgtgtttaa ttataatttc ttcattatct agtggaaaaa caattttatt tatttctgaa
     3421 ccatgagtat taggaagaaa aaaagaagct gttttatctg ttgatatatg ctgtatatga
     3481 ataactggta aattgttttt tctaaaaaac agtagtattt ttttagcatt ttcagcagtt
     3541 tcttctgatt gaaataattc acattttcca tttttaaaat aatcattttg aatatcaatc
     3601 aatattaaag ctatagacat gattatacct cctatttatt tttattataa tactattgta
     3661 aaaaatgtaa attacttact ttttggtatg tataggatta cttattgtag caaattcctt
     3721 tattatctag aatttcttgt tgaccatgtt caagcatata ttcgattcct atttcttgca
     3781 ttatttccac tgcttttaac atttttttac cacgattagt aagaaaatat tcaacatgta
     3841 atggatatcc agcagaactt attttatcaa taatcccaaa atcacgtaac tcttttaatt
     3901 gttgaatcaa cattttttga tttattccat aaatattatg ttgcaattca gaaaatgttt
     3961 tattagattg tcttaattca aatataagga tagttttcca ttttcctttg attatgtcat
     4021 gtacaatttc aagaggacat gtatattcag ctcttatttt catagcatat cacccccagt
     4081 aaaatgataa taaattatat cacttgtctt gtgatatgac aaatatatat gaactgtata
     4141 taaattttat gttttattaa gttctaaatt tcttctattg tagttcatat ttagtacata
     4201 aataattagt aagatataag taaataaata tataacatga ctatagaaat ttaactttaa
     4261 aataacttat gataatttag aggaggaata tatatgaata tatcaagaaa agctatgaaa
     4321 ataatagaat tagcacaaaa aattgcaaat aagagaggta tttcagtaga agaagcttgg
     4381 agtgaagcag taacagaata taaaaataaa tacgaacata ttgcatagat atttaaaaat
     4441 ttagaatatt tggtagaata taatgatttt aaatgatact ataaattata aggtatatca
     4501 ttattaacat agaaggagga tatctgcttg attgtaaaaa tagataatac tttagaaaaa
     4561 gaattttggc aatatgtatc acatgaagaa agtttaaatt tattcataat tggatacgtt
     4621 gagaattatg gatttagctc tcaatatcaa gatatatggt ctcaggtaga aggtggaaat
     4681 ataacctcta taatattaaa aaataagtca acacttataa tttatagttt taaaaataat
     4741 tttaatatag gagaaatgaa gaatcatata aaagatttag atgtagaaag cataagtgga
     4801 aaaaaatgtg taatagatag actaataagt aaatacaaag atttttatga aaaactagat
     4861 aataaatttt gtgtattaaa agaaataaaa gaaatagatt tttccaacat gaaggagtat
     4921 aaaatagaaa atgctcagga aaaagatatt gatgaaatag gaaaactttt aaataggtca
     4981 gactataaag taagtaaaaa ttacatagaa gaaagaaaag ttcatttaaa agagggaaat
     5041 gtaagagcat attttattag aaatgatgat actatgatta gcactgtgtc aactggtatg
     5101 gaaactagtt ttttggcaat ggtggtctct gtaagtacag ataaaagata taggggaaaa
     5161 ggacttgcaa gttatatggt ttacaatttg agtaaagaat tgttgttaga aggaaaagtt
     5221 ccatgtcttt tttataataa tgatgtagca ggtaaaatat atcataatat aggatacaaa
     5281 gagataaatg aatggacaat tctttttaaa tagctataaa aaataaaaaa ctctatcgag
     5341 aattaaagta tttataaata actatatttt tactataatt catgatagag tttttttaaa
     5401 tttatgatac tattttttat tatttaaata atcaagtgtt ttaagtttat aaccttcttt
     5461 ttcccaatgt gtaagaacct catctaatat ctcagtattt gttgatgaat ttggatgcag
     5521 taaaactatt gcaccaggat gagttcttga ataaattttg tttttggcaa attcatgagt
     5581 aggttgtttc ttttcatacc aatctacata agcaaaactc caaaatattg atttatatcc
     5641 taaatcttgt gtatatttta aagattgttc gctaaattta cccattggag gtctaaaata
     5701 cttaggcatt tcttttccag taacatcttt gtatgctttt tctacacttg taatttcttc
     5761 tttgaatttt tcaaaatctg taatacctgc cattgatgga tggctttttg aatgattaca
     5821 aactaaatgt ccttcttttt ccatacgctt tattaactct ggattgcttt ttatataact
     5881 ttcaactacg aaaaattgag ctttagcatt gtgtttttta agcgtatcta ataattttgg
     5941 agtgtttcca ctttcatatc cagcatcaaa tgatagatat ataacttttt cattgggatt
     6001 tcctacataa taagctccgt attttttaaa aaaatcagct tcttttatag gtgatggctg
     6061 tttaccatct tccctagggt taaaatacca atcatattca tgtgtgtcga gtgttggact
     6121 agaaatttga gtttttgttt tatctaatga tttaaaattt atactagcaa ttccaaaaag
     6181 tgttagagca aatgctccta tcataatgta tttttttagg ctatcttttt tcacaatttc
     6241 acctcttatt taaaatttaa agtatatttc ttataatata gtttgaatat ttatagttaa
     6301 aaatattcac atatacaaat aataaatgaa agaagtttac tgtaagatat aaagttgata
     6361 ttaattatct taaataaagt gtatataaat gataaaatat aaagagaaat gattgtaaat
     6421 aagttaggct ggtttaactt gaagggatat aaaaatggat aatataataa gtgtattgaa
     6481 tgatgttgtt tttttagata tagaagttag tggattagat tgtttaaatt cagaaatttt
     6541 agaagttgga gctgtcaagg ttaaagactg gaaaatatat acctatgaat cattaataaa
     6601 aaacaaattt gaggtaccta tagaagtatt ctcagtatgt aaaaatttag ataaaaatga
     6661 tttagaaata gctaataaaa tagaactggt ggaagataga cttgtaaatt ttgtagaaga
     6721 tagtttcatt atatgtcatg atttaagtct gaaaaaaaag ttttttgagt atcatatgcc
     6781 aaagttaaaa aataaattta ttgatttaat tgaattagca gttattttag aaccatatca
     6841 taaagattat agcttagaat acttaaaaaa tactttaaca aattgtaatt ctaaagtgga
     6901 aaatagagct ttatcagatg ctattgatat aataaatatt gtaaattgcc ttttagtaaa
     6961 atttaataac tatgaaaaaa ctactttgga gccattgagt tttaaaataa attcatatct
     7021 taaaaaattt aatcttccaa catgggaatg gagcaaattt ttagaagagg caaattatga
     7081 tttatcaaat aatataaata taaaaaaaga atataatata tttgactcaa aagaagaaaa
     7141 gaagaaggaa agagaaacct taaaaatttt aaatgaagaa gaaaaaaatt atgaagaatt
     7201 attaaaatac aaaactattt gggagaataa agaaggattt acatatgaat atagacctgg
     7261 tcaatatgag cttactaaaa caataagaga gttgtttaga aatagcgaag atgaagaaaa
     7321 aattgcatgt atagaggcac caactggtat aggtaaaagt gtaggatatt tattgcctgc
     7381 aatattagag gctagaatta ataaaaaaag attattaatt tctactgaca caaaggaatt
     7441 gcagatacaa ttaataaata aagatattcc aaatgtgtta gattctttgg gtctaaatgg
     7501 aaaagtaagt tacggatata taaagggaaa aaataactat atttgtatag atagactgga
     7561 agcatatata gatgattatg agtctcaaaa ccctactaaa ggagaaattt tatctttaat
     7621 atttttgaag agattagttg aaggtggcaa gtatggagat atagaagaaa taaattattt
     7681 agtgtttgac aacttcaagg aaataagtac tcacttaaga aatgtaagtt gtgacccaaa
     7741 tatgtgcaga cctaaaaaat gcaaaaaaga ttgtttatat aaaaacagaa tagaagaatt
     7801 aaaagaagaa catataacag tagtaaatca ttcactatta gctaaatggc cgtataagga
     7861 tgaaaaacct ttagaaaata taatagtaga tgaagcacat aatttgactg aaaaaggata
     7921 tgatttcttt tcaagtatta taaattcaaa gtctttaagg tacttattac aagaaattta
     7981 tccttacgag tttattcaaa atagtagctt tatatataaa aaatatagta gaaatatgag
     8041 aaaaataaag gcttttgata aattttataa tgtattaaaa attggaagag aagataaaca
     8101 aaaaattgct agaagtataa atttcattat tgaagagata gattcaatat taaagtttgg
     8161 taattgtaat gaatataata atgtaagtaa ttataattta agatgggaac tgaatttgca
     8221 aatagatgaa attgtgggaa aactaaaaaa agatggtata gatactgaaa taagttatag
     8281 agcctatagt gaaaagataa agttgagttg tgagaaaata ataaaaaatt tagtttcaat
     8341 aataataata atttatagga atattgatga tgatagtata gataaagaag cagatatata
     8401 taaatttgga aaggcaaaga caagagattt agaggatata aagattatat ttgaaatctt
     8461 tttagagtat gatgaaaagg atgattatgc aaggatagtt gaaattgata agaattataa
     8521 tgactttgaa tttcgagtag taccattaaa aatagcagat ttatttgaag aaaatatttt
     8581 atctcaatta gaaaaaggaa tatttttatc agcaactttg agtttatctg aaagtatgtc
     8641 ttattttaaa aatacattag gaatagacag agttaagaat gtggaaaaga ttatagaacc
     8701 aatttttgat tataaaaata gagtctctgt agttggattt tctgatattt gtgagtacag
     8761 aaattctgaa tttccaaatg agatgagtaa aattatatct aatatatcaa agattacaga
     8821 aggtcataca ttagctcttt ttaatagtaa agatagacaa gaaaaaactt atgaaatatt
     8881 gaaaaaatac ttacatagtt ttaacttaga aatttatgct gataaaaagg gcattagaca
     8941 ccttaacgat ttaaatagaa aatgtgtagt acttggctca aaaggatgtt ttgaaggcgt
     9001 agacattcca ggggatggtt tggtttgtgt aactttagac aagcttccga atctaaatcc
     9061 taaagaccct ttgtatttta ctataatgaa gaagtatggt atagactact atactataaa
     9121 ttatcctcaa atgaccataa aggtaaagca agctatgggg agaattttaa gaagcaaata
     9181 tgactatgga tgttttgtga tttttgatgt aggaactaat ataagtgtgt taaagagatt
     9241 agagaaagat ttacacgatt gtaaaatttc aaaggttaat agcaatgagt tttatactta
     9301 tataaggcga catttaaata aatctagaag tttaatacta aaatctgtta tatttgatac
     9361 tataaaagcg ttgaatgttg atgctaaaat ggataacaat gatgttgata aggatattat
     9421 aaaaaaagat ataaatgaaa atataagaca aagagctgta aaaggagaag tgtaccatat
     9481 tgatattata aaaaaagata tgaaagtaaa atattttgat agaaactatc ttataaattt
     9541 agatatattt atgagagaag aagataaaaa ttaagagtgg gagtgatata tttggcaaaa
     9601 caaaagtttt atgctgtgaa aaaaggtaaa aatataggtg tatataatac atgggatgag
     9661 tgcaaaaaac aagtaaatgg attctcagga gctgaatata agagtttttc tacttttcaa
     9721 gaagctaaag aatatattga tgggtcagaa aaattgagtt ttcaagaaga taaggagttt
     9781 atagaagcat atgtagatgg aagttatgaa cattcagtaa aaatgtatgg ttcgggtgtt
     9841 gtgattttaa aaaataatga agttataaaa acttatagtg aaaaaggaaa agagaaaact
     9901 ttagtaagta tgagaaatgt agctggagag atagaggctt ctaaaattgc aatgcagtac
     9961 tgtattgaca ataatgttca aaacttgatt ttatactttg actatgaagg gattgaaaag
    10021 tggtgtactg gagtttggaa aacaaataaa gaaggaacta tagcatataa aaatttctat
    10081 gacagtatta agaataagct taatgtaaaa tttacaaagg ttaaagctca ttctggaaat
    10141 aagtataatg aggaagctga taaattagct aaaaaagcta ttggtgtata ataaaaaaat
    10201 atttatacat aattacatgg tataagagta tatctaaatt cctactttat aattaaacaa
    10261 cttgtaatta aataaatttt gattaaaaaa gcagattgta ttatgaaaaa ataagtatct
    10321 aatttataaa caattaataa tagtattaat tagatacaac ttatttaata taataaaatc
    10381 tgctttttat ataactataa aattttacta cattctatta gaattgccca taaatacctt
    10441 caagttcttc ttttaatact tcagggtcat ttataccaat agacatggtt ctagccagta
    10501 tatttgcttg gtcataagtt gatgtccatg agaatacacc acctagacaa tttctaagaa
    10561 catattgagt ttttaagaat attgataaag catcatcata tgacattgca aaatctccat
    10621 ccttaactaa atacggaact tgagcagtat tatcaaatct atattcatat ccatttttat
    10681 ttatataatc ccttctaagc tcatcataag ttcttgttat agtagcacct aatcttccat
    10741 aaaatggtat accaagaagg attttttcag aaggcattcc agcattctca agatttctta
    10801 ccattgcatc aacactatat cctggcaaag ataagtctga atcaaaaaga tttgcttgat
    10861 gttttctacc atttgggcct gtttcacctg ctgtaaaatc ataactcata agattaaaat
    10921 aatctattat aggagctatt ttatctattt cagcacttga atttatatat cctctatctc
    10981 ctgttccagc tacactaagc catttatcat ctcctataac atctcttatg gcagttagta
    11041 agagtgtaaa gttttctcta tcttgaggtc ttgatgttat tccagatgca ctacttccag
    11101 gatattccca gtctatatct attccatcta aagcatattc atttatcatc tgattgacct
    11161 gtcttgcaaa attatatcta gatgtaggtg ttaatgctgc atcagagaat ccttcagctc
    11221 cccaacctcc aatagctaca attactttta agctaggttt ttcaccttta agagcaagta
    11281 attgatttaa aaatctagga taaggaataa acaaatttcc agactggtct atctcagcaa
    11341 aagcaaatat aactgcatct aatagttgag catctacatt agttggattt ccaagaacat
    11401 attctgctac aattggattt atatctggac agtttgcatt ttcaactatt ggattgtatg
    11461 ggtctgttat ttgtggtcta actaattttt tagaatcttt taaagttttc atagctattt
    11521 ttttagtatt tttttcgcta gtataatcgt agtttttata attatgttta tagaaatctt
    11581 cataactact atcttctttg ttatagctag aatttatttt gtcacaagat tcatctttat
    11641 catagttaaa attcatttca tcacaagact tatctttaaa cttatcttgt ttggagttgt
    11701 gaactttgtt agtattttta gtatgttttt tctcatgatt gcaatcatct ttaatatcag
    11761 tcttgtgttc ttgtttacag tcaagagctt tgttcaggta gtcatgatgt tcatgttcac
    11821 agttacattc attttcaatg tttttagtat gttctttttt ccagctacaa gtattatcaa
    11881 ttttcttgct cacttcttca tcattataat tatctggtac aaaacataag taccagtcca
    11941 tacatgaata tttcttatta caactgttaa ctctattttt taattcctta tagtttttag
    12001 gataaggtaa aatcactggc attccaggaa accagtttgc aggagtaact atattatctc
    12061 tatcactagt ctgaagtgca tctactattc taagtatttc tggaatattt cttcctgtag
    12121 ttagtggata ataaagaatc gttcttagaa tttgattatt atctataata aatacagagc
    12181 gaacagttga tgtatcactc attggttttg atatcatgcc gtataacttg gcaattctca
    12241 tatctctatc ttctataata ggaaatggaa tttctacacc tgtaagtaaa gaaatattat
    12301 acatccaagc taaatgtgaa ctgttactat caacacttag accaattagt tctgtatttc
    12361 tttttttaaa ttcgtcataa tatttagcaa aacataaaaa ttctgtagta caaactggtg
    12421 taaaatcacc aggatgtgaa aataaaacaa tccaattacc cttatagtca gagagtctaa
    12481 taggaccatt tgttgtattg gctttaaaat caggagcctt tgaccctaaa cttggcaaat
    12541 ttggcatgta aatcacccct caataaatta tcatttattt tattctatta attaatacat
    12601 attagtgtta ctattttatt aaaagttaag taatccttat gtcaaaaaaa gatatttatt
    12661 aaaaagattt aatattttcc taatataaat gacaatagta attgctattt ttttactaat
    12721 ttggtatagt aatggataag gggtagtgtc aattttagtg attatacgag gtgagtggat
    12781 tgaaaaaaat tctaagaatt ttagttatct ccatgatgat atgttttgca atgacttttg
    12841 cattagtgtt aataaattca gttatgggag tacatatagg attggattat tactttttga
    12901 tgggaagtgt gcttacagtt tgtttaacaa ttggaattgt tttatgcaat gctagaaaaa
    12961 tatttgatag caaagctata cacaagacaa gaacgaaaac tgtcagtaat aataaaaaac
    13021 aaaagagtca ttctagggat ataaaaagaa agatatcata atttatgtaa aggaaatatt
    13081 tatgtataaa ataatgattg ataggtaaaa taaaaacacg atttaacttg tgtttttatt
    13141 ttttttcaag aattatgata taataaccaa taagaaattt agtttaccat aaaatataaa
    13201 gattattaaa tggagaggga actataatga attttagaga tttatttgag aaggctgtag
    13261 attttattga tgaaaaaagg aaatctatag ttgcgatttc attatcaaca ttaggtgtaa
    13321 ttgctttgat aatagtattt ttcttaagta gtaacgagtt tagtgtagga aatgaagcta
    13381 atgagttgtt aaagattata gagaaaagac agtattctat agctgttgat tactacacaa
    13441 gtatagaaaa aaagttttct gattcaaaaa tggaaaggtt taataagtct gtttctaaaa
    13501 aaataaataa attgctatta aatagtggtg ataaatattt agatggagac ataagtcaag
    13561 aaagttttat tggattaata aataccgtga aagaattaaa caaaataagt atagatgtgg
    13621 atgacttatt agctcaagct gatagagtta gagaaatgta taaagaagaa aatactactt
    13681 atgatattgc cattaactac ataagtactg tttcaatatt aaatggtatg ggtagtaacc
    13741 tagatgtata caaacagaat atagaaacaa tcaaagagtc tagagatgtt tatgactcag
    13801 cagtaaaaga ccaaaaagca tataagtatt atgaagctat tgaaaagtat aataaagtat
    13861 taaaagaaga tgaaaagtat tacagtatgg ctcaaaatgg gaaagaacaa tgtattgaag
    13921 aaatgtatga ttactatata agtagagctg aagaggcaaa tacttctgga gattatgaaa
    13981 gagcattaca atatattgag tatttaaaag acgattattc agatgatgaa aaggtacaga
    14041 gtttagaaaa aaaatataaa aagaatttat cattgtatac tttaacatct gatgacatta
    14101 taaatgtaat agctaaaaaa agtggcaaag acaaggcaaa tctatctata aattcacttc
    14161 cacaaatgat aaaaaataat aaatactatt atgctgaagt atatgagtat gataaattaa
    14221 taaatgaagt tttggtaagt gcaaaaacta aagatttata ttcatataaa gatggtaaaa
    14281 aagattacaa agtagattat ggtgatggat actttagaat attagaagat ggaagttatc
    14341 aatttggtat tacaaaagat aaagctaagt ttgtgttaac taatactctt gatgaaaaag
    14401 aaaataagta taaaaagatt gagatattag atatagagaa agcagataga tatgtaaaaa
    14461 gtaaaaagag tttagaagaa ttgtttggaa aatataaaaa tatttattat tatgctgtag
    14521 taaataaagg cttatttaga ggcaaagaag tttatgctat taatatttac aatgaaaaaa
    14581 tatatgccat atcagaaaat ggactaaatg aatattaatt aataatatta aattaatata
    14641 taattaaaaa gtttttgggg ttttaaggcg cattatgtag taatataata atagggatat
    14701 ataaataatt ttattgtaag gagaagtatg ggatgagtaa tgtgaacaaa aagctagtta
    14761 tagctattgg agctgtagca ttagtagtaa taatttttat aggcataatg tgcatgcaat
    14821 ttaaagggga gaaaatagca aaaaacacat atgttaatgg agtaaatatt ggaaaattaa
    14881 ctaaatcaca agcaaaacag gaattagcta aaaaatacaa attagagaat gttgatttta
    14941 attacaatga taaaagctgg aaagtaaaga gcaaagattt aaatttatct actgacctgg
    15001 ataaaacagt agaaaacgca tataatttaa atagaaagag tgctttcttt ggcaatctat
    15061 caaaaactat ttcagcaaat tttggcaaaa aaagcaactt agtagttgcg ataaattatg
    15121 ataaaaataa attaaaagca gaaatggaaa agatagctaa agaaatagat gtagatgtaa
    15181 aagatgctac acttgatata agtggtgaaa aagtcaaggt tataccagat tctgatggtc
    15241 ttaaaatgga tatttctaag agtatggaga attttgataa tcaaactaaa aaaggtaact
    15301 ataaaaatga gttagtagta aaagctactc cagcaaaagt aaaaaaagag caacttgcta
    15361 atatagatac aaatttaggt acgtattcaa caacatttaa aacttctcaa ataaatagaa
    15421 gtataaacat aaaattagca acagataata taagtaatgt attacttatg ccaggagaaa
    15481 ctttctcatt taataaacat acagggaaaa gaagtaagga aaatggatat aaaagtgcac
    15541 ctgtaataat ggaaggtgag atggaagaag attatggtgg aggagtttgt caagtttcat
    15601 ctacgttata caattctgtg ctatacgcag gtttagaaat tgttaatgta aaaaatcata
    15661 ctataccatc aagttatgtt ccaaaaggaa gagatgcaac tgttgcagat agtggaatag
    15721 atttcttatt taaaaataat ctaaagcatc cagtttacat aaaaaattac gtttcaggaa
    15781 atcaaattgt ttgcaatata tatggaagtg cagaagataa acaaaatata acaatatcaa
    15841 caaaattaga tggcgtttca caaactacaa tgaaaagagt taatgaccct acaatgccta
    15901 aaggtaaaga aaaagtagac aaaagtggaa gaaatgcata ttctgtatca acatatagaa
    15961 catttaatga tgcaaatggt aaaaaaatta aaactgaaaa aatagctaat tcatattatc
    16021 ctaagaagga aggtattata ttagttggga ctatggaacc aaaaccagag gaaaaaccaa
    16081 atacagacga aaataagaat aatcaaaata caaacaatca aaacccaaat aatcaacaaa
    16141 aaccagaaac accaccaact gataataagc ctaatgagac acaaccacaa ccgcaagctt
    16201 aaagttctca agaataggat ttatgtagag taataaaaaa tataaatcta aataggaggg
    16261 attactttga atttaaataa tataacgaat tacgttcaaa gtatttgcga gaatatttct
    16321 aatgtcttgg atgtagatgt tactttagtt acaaaagatt taactaggat agcaggtaca
    16381 ggaatattca gaggtaaaat aggagagaca atatcagaga agtcagtgta ctctcttgtt
    16441 ttaaaagatg ggaaatccta tgttataaat aaagaaatag aagagaactg taataaatgt
    16501 gcaaatagag aaaattgtaa agagttagct gatatatgta ctcccgttaa aatgggagag
    16561 catatacttg gaatcttggg tatagctgcg tttaatgaag aacaaaaaga aaagatactt
    16621 tcaaaagata aggagttaac tgcttttgta aggagtatgt ctgatttaat atcttttaaa
    16681 ctagatgaac tttataaaca agaagttaag actatagatg accttgagag ggaagctata
    16741 gaaaatgcca taaagaaata tggaagtaat acagaaggta tgaaaaaagt agctgaggca
    16801 ttaaatatag gtatagctac actctataga aaagtaaaaa aattcaacat taaaagttaa
    16861 tagtattgaa aaagaggtaa cctttttatg aaaagaagag gattaccttt tttattatga
    16921 gaatggtgga aaaatatgta tagttttgac ttgacatatt aaatatgtta tcttaaatat
    16981 atattttaga gtggaggtga gtattatttt agttaaagat ataaaacaag acatagaaag
    17041 catgcctaga aaaattttag atatatcttt gatagaagat aataaaagtg atttgacttt
    17101 ttttaatata gaagaagaag acggtgatga aacattaaaa gcattaaaac agagttatgt
    17161 gactacaaat tataaagaag aaactctatt aaacttgcaa ggagctttaa attcaaagtc
    17221 agatacaacg tctaaggagt taaaattaga atcatataaa agatataaca atgcattgga
    17281 tttagcatat aaaaattata taactagtgc cattaatatg gttaataaag ctctggagat
    17341 aaatcctaaa gacattgata tactaaatct tagaggtctt ttaaaattat taaaatgtga
    17401 ttttgctaaa tcatttgaga gtttttatac tgctttatgt tatgaaaata atcatatatc
    17461 tagaaaatat gtaaatctaa tttcatctga agattttaaa acttttttag gaagatacaa
    17521 tcattctata agatttataa atgaagaatt aaattatgag tcaatacata ttttagagaa
    17581 cataattgaa gaagaacctg aactaataga gccatatgta attttatctt tgttatatga
    17641 taaactaggt aatgtaaaaa agagagaagg atatttagac aaacttaaag agctagataa
    17701 agataatcct gtatttgaaa aaaatgaaga agaaaaagaa gatacaagta aaaaggaaga
    17761 aataaaaaaa gtaaaaagaa agaaaagtat tttgccatat attatagttg gctgtgtttt
    17821 aataggtatg gggatatatt tgattcaaag caaaaagaga atagaaaact tgaataacca
    17881 aataagtagt aaagaggaaa agttaagtga aactgataaa aagttaggag aaacgagtaa
    17941 aaaattagaa aaaacgaata aggaattaaa tgaggttaaa aataaagaac cagaaagaga
    18001 gataactgta gctgatgagg aagatttata ttatcaagct ctaaatttaa agaaaaacaa
    18061 agaatatgaa aaagccatag ataattttaa aagtgtagtt tcttctggta aaactaaaaa
    18121 atatatttct gagtcaatat atcaattagc aataacaaat aaattattag gaaataagga
    18181 tgaagctata aaatattaca aaaaatatat aaatacttat actaaaaatg accagtatta
    18241 tgatgattca tattacgagt tgggtatgct ttattatgat aatggcgatt taaaaaatgc
    18301 acaacagact ttttatagtt tgagaagtga agttccagac agtatgtata acaattcaaa
    18361 aataaaagaa attttaagtg aaaaataggt ttatatagtt aagttttttg aaacaaccaa
    18421 gtatgtattt tattaaatta aaataaaaat aaatttaaaa agagattgtg tcaaattata
    18481 actttctatt ttaaagaaag atatttgctt gttgataaaa ctacaaatat atgatttgaa
    18541 gcaatctctt taatttttgg aggtggaaaa tgaaagtttt caatcaattg gtaataattt
    18601 tatctatctg ggtaatagga gagtatataa gttcctttat acaaggaatt atacttattc
    18661 ctgggagtat agttggtatg ctattattat ttctactact acaatttaaa gttttagact
    18721 tgagtagtat agaaaatgta agtggatttt tcctcgataa tatggctata ttttttattc
    18781 cagcaggtgt atcacttata aagtcattag acctaataag ggaaaatgta ttagtgcttt
    18841 tattagtcat atgtttaagt acactaatag taatgtatac tactggaatt attgtggaga
    18901 aaatgataaa aaagaaggaa gaaggacaaa aaaatgtata atgtattaca gacaccagta
    18961 tttggtataa tagtaacaat agtttttttc aatttaggaa gatacattca acgaaaaaca
    19021 agtaatccta tatgtaaccc tttattaatt gcaatcgtag gaataatatt gtttttaagc
    19081 atatctaaaa tcccttatga gaattacaag ataggagctg atagtctaaa tttcttttta
    19141 ggtcctgtca cagtagtact tgcagttcca ctttataaac aatttgaatt atttaaaaag
    19201 catatgtttg agattattgt aggaataggt tgtggtatag tgatttcttt tgtatctgta
    19261 ttgataattg gcaaaatagc taattcagat gtaagtataa taaattcact aattccaaaa
    19321 tctataacaa caccaatggg aatatcttta gcaaattctt taaatggtgt agaatcaata
    19381 acagttgtag ccataatttt tacaggtatt tttggtggta tggttgcttc tacagtattc
    19441 aaactgggga atataaatca tccagttgct aaaggaattg ctcttggaac atctgcacat
    19501 gctttaggaa ctacaaaggc ttttgaactt ggagaaatag aaggagctat gagtggtgtt
    19561 tctattggag tctctggtac aattacagta atactaattc caattataat gaattttata
    19621 taaaaaataa aattaagacg agtaacttga atacttaaaa caaaataaaa taaaaaaaat
    19681 ttaaaataaa aactgaacga aaaaaatgca aataatgaaa taaaaaaatc atgtactgaa
    19741 attataaaaa gaaaaatttc atttaggaat taattataaa gagacaatta ctaaacttga
    19801 atttgctaaa ataaaataaa ttactgcgaa aatagatatt tagaaaaaaa tactataaat
    19861 ttactatatt gcaagttaaa taataagcag tatcatatta tgctagaaaa agtttcattt
    19921 aaggcataaa tgagatgatt tgaacgtttt taaagattag aatataaaag attgcactag
    19981 acatatatga aaaagataat ataatagatg atgtaataga tgacagttca agaaattata
    20041 aaaaaaattt atttgaaata ttatctatta catcaggaat aatatatgta agagtaagct
    20101 tttaaaattc taaagattta gaaagattga agggagaaag aaatgagtga agttaagaat
    20161 accctacaaa aacatccagt tttaagatat tcaacaatgc tatttgggat gttgatgaca
    20221 tctataggaa taaatgggtt cttaagacca gcacatctac ttagtggagg tgctacaggt
    20281 atagcaacat ctataaacta tttgacaaat ataaatgtag gtttattaac atttttaatc
    20341 aatattccaa tatttatctt agggttcata taccttgaaa aagagttttg tatttcaagt
    20401 ttggtaaata tgattgtatt ttcattatta ttaggagcaa ctcaggaaat aagtaatatt
    20461 atacctatac atgatatatt gcttcaaagt gtatatggtg gtatattatc tggtttagga
    20521 gtcggagttg tatttagaac taggtcttct caaggtggta cagatataat agctgcaata
    20581 ctaaaaatta agaagaatat agaaatgaaa gacactgctt tagcaataaa tggcttgata
    20641 gtacttacag gaagtttttt atttgggttg gatttagcat tatacactct tataggtcta
    20701 tttctaaatg cgtattcaat gagttttatt aaagatgcaa tgaattacca aaaatctgtt
    20761 atggtaatgt caaatgaagt cgatttaata gcagaagata taatgaagag tttagttaga
    20821 ggtgtaactt ttttagatgc agaaggtgca tacactcatc aaaaaaagaa gattatatat
    20881 acaatagttt catcaaatga gataccaaag ataaaagata tagctttgaa gtatgataaa
    20941 aaggccttta tatctgtaaa tgatgttaca gaagtaaaag gaagagggtt taaagcaaaa
    21001 gatttataga aaattttaca agctgggagt ttataatgta aatttgtata ttatatctct
    21061 cagcttattt aaatttagta tacgaaaata aaggttttat taatgatttg tgtatcactt
    21121 taaaagatat cattttaaaa ttaaaattga aaaaattact taatatgtag aaaacatgac
    21181 cactattagg atataataaa tttaatagat ttagtaaaat atctaggaat aacgttggag
    21241 gaatggcatt atgaatttat ctaaagaata tgttaatttg tatgataatt atttgaaata
    21301 tataaatgaa gtaaacaaag agattagaag tataaagaac atgaagaaac gtgttttaaa
    21361 aaggggcgat tttgctccag aaaatgaagt attagaattg gaaggaaaaa caatacgcga
    21421 tatagatgat gtcgatacaa aaaaaccaaa aaataaaatc tataaatttt caaatgggga
    21481 tgtatatgta gggaaattct tagagggaaa gatggagggg aaaggctcat atactttttt
    21541 tgtagatgaa ggaacagtta tggagtacat aggagaattt aaagaagata aaaaaaatgg
    21601 aaaaggaaac tttatatttt caaatggaaa tgaatatata ggttattttg aggaagatat
    21661 gatgagcggt attggaaata tgttatatag tagtaaagat gaatatattg gaacttggaa
    21721 aaacggaaaa aaagatggaa aaggtattta taagtggagt gatggatgta tatatgcagg
    21781 tgaatttaaa ggtggaaaga tggaagggta cggtatttgc tataatagta aaggggaagt
    21841 actttatgaa ggagaatgga agaataattt gattcatggt aagggaactt atatatggga
    21901 aaaaggtaaa aagtatatag gtgaatttat gcatggtaaa aaacatgggc aaggaacttt
    21961 ttatctaaat aatgaattgg tttatgaagg gacttggaaa tttgataagc catctatatt
    22021 tgatagaaca ttagatgaaa tattttcctt gagactgtag ctttatctaa ttagtagata
    22081 aagctttttt ctaatactta ctgtaaatag gtatgaatga tattgattag tatacactat
    22141 caatattaac ttaataaatg caatattaaa aaattttgat tgattttaag aaggagagat
    22201 atattgaaga gattaattgc tttagtgtta gtagtactta ttgttttatt ttatagtcct
    22261 gaattattaa aagaaggata tgatttaaaa gaaaagtttt ttcaaagtga aatatggaat
    22321 gaatttttag acaaaataaa tataaatgat aattctaaga aagataaaaa agaaaaaagt
    22381 caaaatttac aatcaaataa tactgaaggg gagaacttag gagagtcaga tataaagaat
    22441 tttgaaaaaa taagcttagg agataattta agctatgttt tatcaagtat cggcaaacct
    22501 ggtagaattg atattagtga atatggtttt gattggtatg tatataatca atatggaaaa
    22561 gaatttgcaa tggttggact tgaaaatgat gaagtagtag cactttatag taattctatt
    22621 aattcatgtg aaaatcaaga tataaaacta aatcaagata gacaaacagt gagaactaag
    22681 attacaccat taaaatataa gagaaaagga aataccagat atataataaa ctcagaaaat
    22741 caatatgata taataagtaa ggaaggtaag tatattacaa ttttctacga tattcatgaa
    22801 gaaaatagag tttgttcata tttaataatt gataaaagca ctgaagatga gtttaaaaat
    22861 ttatatccag atgatagcga agaacttaaa aaatgttttg aacttgaagt tatagacctt
    22921 gtaaatagtg ttagaaatca aagagggtta aactcattga gatacagtga acaggcaact
    22981 ttgagttcaa gaaaacatag tgaagatatg agagataata atttttttga ccatgtaaat
    23041 aagaagaatg aaactccatt tgacagaatg aaaagagaag gtatagtata tacttcagct
    23101 ggagaaaaca tagcagcagg acagattaat gcaatatatg cgcatgaagc ttggatgaac
    23161 tctgaaggac atagaaaaaa tattttgggg aactataata atattggagt tggagtaata
    23221 tttggaggaa gctataaaac atattacact caaaattttt ataaataact aaaatatttg
    23281 aaaggaagtt aaaaaatgac atcatggaaa aaaaagacag tatataagtg cttaatagca
    23341 gtagtcttgt tttgtggaat agtgttaata tctaatttta gtaaagtttc tgctttgatg
    23401 atggatacta atggaaatgt tttgattaaa catggttcaa gggaaaaaaa gctaatagca
    23461 attacctttg atgatggtcc tcatcctaaa gaaactagtc aagttttaga tgtattaaag
    23521 aaatacaatg taaaagctac tttttttata gctggaaaac atgcaaaatg gtataaagaa
    23581 ccattagtaa gagcaagtaa agaaggtcac gagataggaa atcatacttt caatcatcct
    23641 gatataagta atttaagttc tagtcagata gaagaggaga ttgttaagtg tgaagacatt
    23701 ttgaaagaag taactggaaa aaaaccgaca ttatttagac caccatttgg aagttataga
    23761 gaaaaagaat taatagaaat tgcaaaaaag catgactata aagttgtttt atggacaggt
    23821 gtagatgtga aagattggaa aaatccagga gctaatagca ttgcagataa aataattaat
    23881 aaagtacaaa atggagatat aatacttttg catgattatg caactaatga tacagttgaa
    23941 gctttagata tgtttattcc aaaaatgatt gaaaaaggtt ttaaatttgt aacagtttct
    24001 gagttaataa aataattttt aggggggaga tttacagtat gattcttatg atagacaatt
    24061 atgattcttt tgtatacaac ctagtccaat atatagaaga attaggggaa acagttgtag
    24121 taaaaagaaa taatgaaatc aaaataagtg acattgaaga actaaatcca gaggtaattg
    24181 tgttatctcc aggaccgtgt tctccaaaag aagctggtat ttgcatagat attgttgagc
    24241 attttaaggg gaaaaaacct atactaggaa tttgtttagg tcaccaaact attggacatg
    24301 tttttggagg agatattata aaagcacaac agcctgtgca tggaaaagta tatagtatca
    24361 accatactaa taaaggagtt tttaggggac ttaaaaatcc tttaaatgtc actaggtatc
    24421 attcactaat agttgactcc aatacagttc caaaagaatt agaaattaca gcaattactg
    24481 ataaagggga aataatgggg attaggcata agaaatattt aatagaagga gtacagtttc
    24541 atccagaagc tattttgtca gagtatggtc atgaaatgct taaaaatttt ataacagaag
    24601 ctagagaaag ggtacatatg taatatgata agagagataa atactaaatt aaattctttt
    24661 gagatattta ctatttttag aaatgaacat gacagtttta tattagacag tgctatggac
    24721 aaagaaaaat tgggaagata ttcttttata agtagccaac catttaaggt attaaagtat
    24781 aaagatactg atgaaaatcc tttagaagtt ttaaaagaag aactacataa gtatagggtt
    24841 gtaaatgata ctaatcttcc atttgtagga ggtgctgtgg gatatttatc ttatgattta
    24901 ggtaattaca tagaaaattt acctagaact gctgtagatg atattgagat gcctgatatg
    24961 tattttggat tttataatca tgtaatagtt atagaccatc ttgtgcaaaa aacttatata
    25021 gctactccaa acatagatat cgaattagaa gaaaagataa tagatgatat agaacaaaga
    25081 atattaaaag aagagaaaaa aggtatagat agcatatgtt atgaagaaaa agaagtaaca
    25141 cctataagac ttaaatctaa ttttacaaag gaagaattta aaaatgcagt tcaaagtgtt
    25201 agagagtaca taagacaagg agatatatat caagctaatt taacacaaag gttcagtgga
    25261 gaaacagaac ttacaagctt tgaattgtat agggacttaa gaagatttag cccagcacca
    25321 tttggggcat tcttaaactt tgaagatgca catatattat caaattctcc agaaagattt
    25381 ataagatgtg ttaataagag aatagaaact agaccaataa aaggtactcg tccaagaggg
    25441 aaagataaag aagaagattt aagacttcaa caagaactta gaaatagtga aaaagataga
    25501 gctgaactac ttatgatagt agatttagaa agaaatgata ttgggagaat atctaaaact
    25561 ggaagtgtta aagttccaga gctatttgta attgaaccat atgcaaatgt aaatcactta
    25621 gtttccacag ttgtaggtga gttaaaagat gataaagatg ctactgatgt aataaaagca
    25681 acttttccag gggggtctat aacaggagca cctaagatta gagcaatgga aattatagac
    25741 gaattagagc caacgcaaag aaatgtatat actggttcaa taggttatat aggttttaat
    25801 ggtgatatgg attttaatat agcaattaga acaataatca aaaatgacaa aaaagtctat
    25861 tttcaagttg gaggaggaat gacttgggat tctgacccag atgaagaata tcaagaaaca
    25921 cttgataaag ctaaatccat aatgaaggct ttgaggggat attatgaaga ataatgtagg
    25981 ttttgatagt agtttaagta aatttggaat tggtttgttt gaaactatta gagttaaaaa
    26041 tggaatagca gtagatttag atatccatat agaaagaatg ctaagttcaa taaattgttt
    26101 ggatttagat ataaaatata aaaaagattt cttgataaat gaaattgtta catatataaa
    26161 aaaagaaaat gtcattaata aagcacttag aattactgtt tttgatgaag gttataatat
    26221 atctattagg gatattccat ataatcaaga gacgtatgag aaggggttta aattagctat
    26281 atctccaata gttaggggga atagtttaat tcatagacat aagactacta attattttga
    26341 aaacatatat accaaaaata tcgcaaataa gactggttat aatgatggta tatttttaaa
    26401 ttcagaaggt gtaatattag aatgttctat gagcaatatt ttctttgtaa aaggagaaag
    26461 agtgtacact cctagtgata gattaccgat attaaatgga ataataaaaa aaaggattat
    26521 agagatttgt gacgaattac atatagagtt gatagaaaat gaaattaata tatcagaaat
    26581 tagtagtttt gattttgttt ttgtcacaaa tagtcttatg ggcgctataa aggttacaga
    26641 aattgacaaa ataaaattta ataaagaaaa tgttgttttt gataaaatag tgaagttatt
    26701 agaataaatt aaaatattaa caatttgttg gagacaaaag atgataggtt gtatttatga
    26761 agtatacaat gaagagataa ctaaaataat agaaaaccaa aacactttgg ctgtatattt
    26821 agtgggttct agtaaagacg tagattttac tctttatgat gtagagataa acgatattga
    26881 tgtgttcgtt tttgtaaaag aaggggaaaa acaagagaga atactgttta aaaaaaaggg
    26941 aatagaattt gatgtaaatt acttttcaaa agatggtgta aaaaaattat tatcaaatag
    27001 ggaatatttc tttgtgaaag aaatgaaaga tgctaaagta ctgtttgata gggagaatat
    27061 atcacatatt ataaaagata taagtagaaa tatttactta gaaggaccca gtaaaatgtc
    27121 attagaggaa aagtctttta taaagcaaga tattggagca aaaatatcga atttaaaaaa
    27181 taaagaaaaa tttgatgttt ttgaatatca ttttttgacg aatttatatt taaaagatat
    27241 aataattggg tactttaata taaatgataa atgggtacca aaagacaaaa aattgctaaa
    27301 agttttaaaa aaagaaaata atgagctttt tgaactagtg tcaaaagtaa gtgaaaatta
    27361 tgactatcaa agacttttag atgtttataa ttatattttt aaagaaattg agacaaaaga
    27421 ggttataaaa ctaatcttct agtcacaaat caatgggggg agtttaaatg aataaagttg
    27481 ataaagaaaa gatacaacat gcagtaagag aaatactaga ggcaattggg gaagacccag
    27541 atagagaagg tctaatcgaa actccaaata gagttgctag gatgtatgaa gagatattct
    27601 ctggtcttag tgaagaacca agagaccatt taaaagttct ttttgcagat gaaaaacatg
    27661 aagagttagt attggtaaaa gatattccat tttattcatg ttgtgagcat catctagttc
    27721 ctttctttgg aaaagctcat attgcttatt taccaaaagg aggaagactt acagggcttt
    27781 ctaaacttgc tagagtaata gatacattgg caaaaagacc acaattacaa gaaagaatca
    27841 ctaaaaatgc tgcagatata ataatggaag aattacaacc ttatggtgtc ttagtagtag
    27901 tagaagctga acatatgtgc atgacaatga gaggcgtaaa aaaaccaggt tcaaaaactg
    27961 ttacatcagc agtgagagga atatttgaaa aggacattgc gtctagagcc gaggctatga
    28021 gtttgattac tatgaagtag caatttatta tagatataat catttattga gataaaattt
    28081 aatttaaggg agtgtcatta attgtgtttg attatggtaa aagaacttat ataatgggaa
    28141 tattaaatgt aactccagat agtttttctg atggaggaga ttttaataac ttggacatag
    28201 caatacaaca tgcaaaagat atggttgacc aaggtgcaga tataatagac ctaggaggag
    28261 agtctacacg cccaggtcat agctatgtag actcagacga agagctaaga agagtaatcc
    28321 ctgtaataaa aaaacttaaa caggaattgg atataccaat atcaatagac acttataagg
    28381 cagatgttgc agaagaagca ttaaaattag gtgtcactat ggtaaatgat gtttggggtc
    28441 ttagaaaaga taaaaatatg gcttctgtaa taggaaaata tgatgcagaa gtgtgtataa
    28501 tgcataatca agatgggaca aactatgaca aagatataat ggagtcaata aaagactttt
    28561 ttaaggtaag tatagaaatg gcaatgagtt gtggtgtaaa aaaagaaaaa atagtacttg
    28621 acccaggtgt aggatttggc aaggattttg aacaaaatat tgaagtattg agaagattaa
    28681 atgaattaaa agatttaggg tatcctattt tgcttgggac atccagaaaa tcagtaatag
    28741 gaaaagtact tccagttgag cctaaaaaaa gattagaagg tacaatagct actactgttc
    28801 ttggtataag agatggcgta gatatagtta gagtacatga tgtttatgaa aatttaatgg
    28861 cagctagaat gactgatgca atatatagaa agtaggtata atataatgga taaaatatta
    28921 cttagtaatc taggattcta tggatatcat ggtgttctta aagaagaaaa ttttctaggt
    28981 cagaaattct ttgtcgacat ggaactttat attgattcaa gagaagcagg tcttagtgac
    29041 gatataaata aatctgtaag ctatgccgag gtttacaatg ttgttaaaga tattactgaa
    29101 aataaacaat ttaatctttt ggaggcttta gcggaaaata ttgctgaaga agtcttgaat
    29161 aaatttatac ttataaatgg agttatggtc agagttagaa agcctgaggc tcctgtaaat
    29221 ggtatttatg actattttgg tgttgagata aggagaacaa gagatgaata aggcttattt
    29281 gggaataggt actaacatgg gtgatagatt tgataattta tcaagagcat gtgaactttt
    29341 gaaaaatagt gattctatat ataaagtaaa agaatcaagc ttatacgaaa caaaaccatg
    29401 gggatataca gaacaagcag attttctaaa tatgtgtgta gaaatagaaa cagagtttga
    29461 accttatgag ttgttagaat attgtcaaga aatagagaga gaactacaca gagagagaat
    29521 agttcattgg ggaccaagaa ctatagatgt agacgtacta ttttttaatg atgtagtttc
    29581 cactgatgaa agactaacaa tacctcatcc aaggattcaa gatagagctt tcgttttgat
    29641 accacttatg gatttaaatg aagaacttat aataaatgaa aaaacaataa aagaacattt
    29701 aaacctccta tctgctgaag aaagagaaga agtaaaggag cttgtaggtt atgaaagaaa
    29761 acctatttaa taataattca aagatagaga taaatacaaa taacaaaaag ataactgtaa
    29821 aaaaagataa acttataata gctggaccat gcgcaataga gagttatgag caacttttgg
    29881 agactgctaa atttgtaaaa agtcaaggag caaacatttt aagaggtgga gcatacaagc
    29941 caagaacatc gccaaattca tttcaaggat taaaaaaaga aggtcttgaa atattaaaag
    30001 cagttaaaga cgaagttggt atggctgtta ttacagaact tatggatgta agagatatgg
    30061 acgaactgta tagtataagt gatataattc aaattgggtc aagaaatatg caaaacttta
    30121 ctcttttaag tgaagtggga aaacaaaata aacctgttat gttaaaaaga ggaatagcat
    30181 ccacaattac tgaatggata ggtgcttctg aatatatagc aatagaagga aatagtaata
    30241 ttataatgtg tgagagaggt ataagaacgt ataatgatta tactagaaat acattagatt
    30301 tagctgcggt acccattatt caaaaggaaa caggtcttcc tgttgtggta gacccaagcc
    30361 atgccactgg agttagatat ttggtaaaac ctatgtcact ggcatctttt gcatgtggag
    30421 cagatggaat aatggtagaa gtacatcctg acccagaaaa tgctttgtca gatggtgctc
    30481 aatctctttg ctttaatgaa tttgaagatt taatgaaatc aattaataat tattaaaaga
    30541 ggcaagagcc tcttttttat tcgtaatcgt tgctaaggta aatttataag ttataatttg
    30601 atagttagat tatttaatat aaataaagat ttaatattga tagaattaat ataaaaaata
    30661 aaaatttttt gattaataag aaggatatca ataaaaaaag tcgaattgtg tatattgagt
    30721 gattgacaaa tttagaatat agtgtagaat agaaatgtta acacaaaaaa ttacaccaga
    30781 aggtgataat atgaatgata taaaagacat tattgaagaa ataaaagcta gatgcgatat
    30841 agcaagtata atatctgaat atatgaatat aaaacaatct ggagctaatt acaaaggatt
    30901 atgtccattt catggcgaaa agacaccttc tttttatata aatacatcaa aacagattta
    30961 taagtgtttt ggttgtggtg aaggtggaga cgtaataaat tttgtcatga aaatggaaaa
    31021 tttggatttt atggatgctg taaaaatttt agcaaataaa tgcggtatag aaattaacac
    31081 taacatgaat gaagaaacta ggattaaaat agaaaaatct aagaaatttc aagatattca
    31141 tacggaagca gctagatttt atctttcaaa cttattggga agcaaaaatc ttgggtatga
    31201 atatttaaga ataagaggac tagatgataa aattattaag aaatttggtt taggattttc
    31261 tttggattca tggaattcac ttatgaatac tctaatcagt aaaggatata aaaaacaaga
    31321 cttattagag tgcggtctaa ttgcaaaaaa tagagatgga actaattgct atgataaatt
    31381 tagaaataga gttatgtttc ctatattcga ttatagagga aatataatag gatttggggg
    31441 aagagtatta gacgattctt tgccaaaata cttaaattct ccagacacat taatttttaa
    31501 taaaaaacag aacttatacg gattaaattt tgctagaaaa aatttagaaa gtaaaactat
    31561 agtcttagtt gaaggatata tggatttaat ttcactttat cagtatggta taaaaaatgt
    31621 agtagcaacc cttggaacag ccttgactga acaacaaggc attttaataa agagatatgc
    31681 ggacactgct attatatctt atgattctga tgaagcagga ataaaagcga ctttaagagc
    31741 tatagatata cttactaaat taggtatcaa tgtaaaagtg ttagacttaa aagatgctaa
    31801 agacccagat gaatttgtaa gaaaatacgg acttagtgat tataaaaaag ctatggatgt
    31861 ttctactcac tacataaaat ataaaataga tcatcttaaa aaagaattta acattcaaaa
    31921 agatgaagaa cgagtgaagt tcgcaaaaga agcttctaaa attataaaac aattgacaag
    31981 tcctgttgaa attgattttt atacaaagta tttaagcaat caaatagata ttaatgtcga
    32041 gtctataaag agagaagttt atggtaaaaa ttacaataag ccatataata acaaaaatca
    32101 aaagaaaata gaagaaaaag taattgaaaa agtcgaagtc agacaagacg gaaaacaatt
    32161 agttgaagaa actctaataa aaataatgtt agaagacaaa aaaattagag aaatagcgtt
    32221 acttaaagta gaagaaagtg attttttatt gaaagaaagt aaagaaattt taaattacat
    32281 gattaaaaat caagaattgg acaaaataac tattgacaaa ttgaaaagtt taaacatatc
    32341 cgaagaatac ttaaaagaat taaattcaat ttctttgaat agtataaact tagagaacac
    32401 aaaagaaata gaaggaataa taacaaatat cagaaaaaac tcattagaag agcaaattaa
    32461 tagcttgttg agagaacaac aagaattaga aaataataat gatatgaaag aggtagatgg
    32521 tagagttatg gaaattgctt taaaaatagt tgagataaat aaaattttaa agagcttgta
    32581 gagaaaggag gtttgagtgt ggaaaataaa tcgaataaaa aagagttaaa aaaggttact
    32641 gctaagacat taatagaaaa aggaaaaaag caaggttctc tgacacttgc agagataatg
    32701 gaagcttttt cggagactga acttgataag gatcaagtag aaaatcttta tgagacttta
    32761 ggaaatttgg gaatagaaat aacagaaaca aaaaactata aagctgatat agatttttcg
    32821 gttgctgatg acgatttaag tataggccac ttagatgaag atgcagaggc aatttcacat
    32881 gatgactctt ctgcaataga aatagaaact gtggatttat ctttaccaaa agggataagt
    32941 atagatgacc ctgtaagaat gtacttaaaa gaaataggaa aaattcctct acttaaacca
    33001 catgaagaag tagaatttgc tagaaggatg cacgaaggtg atgagatagc aaaacaaagg
    33061 ttagttgaag caaacttaag actagttgta agtatagcaa aaagatatgt aggaagaggt
    33121 atgcttttct tggatttaat acaagaggga aatttaggtc ttataaaagc agtcgaaaaa
    33181 tttgactata caaaaggata taagtttagt acttatgcaa catggtggat aagacaagct
    33241 ataacacgtg ctattgcaga ccaagctaga actataagaa taccagttca tatggtagag
    33301 actataaata agctaataag agtatcaaga caactacttc aagaacttgg aagagatcca
    33361 aaaccagaag aaattgcaaa agaaatggaa atgacagaag ataaagtaag agaaataatg
    33421 aaaatagctc aagaccctgt gtctttagaa acaccaatag gagaagaaga agatagccat
    33481 ttaggtgact ttattccaga tgatgatgct ccagccccag cagaggcagc agcatattct
    33541 ttattaaaag aacaaataga agatgtactt ggttcattaa atgatagaga acaaaaagta
    33601 ttaaagctta gatttggtct tgaggatggt agagccagaa ctcttgagga agttggaaaa
    33661 gagtttgatg taactagaga gagaataaga cagatagaag caaaagcact aagaaaacta
    33721 agacatccaa gtagatcaaa aaaacttaga gattatttag actaaaaaga tacatcattg
    33781 atgtttttgt gataaatgcc atgagataag tgatatctca tggctatttt gtagtaaaga
    33841 tttaatttta tttttgtagt tatttcagtc taatatctat aacttggatt aaatcctata
    33901 aataaaggga attgaaagga gaattatatt tgaaattaac agatagatta ttgaaaatag
    33961 catcattagt gtcagatggt aaaaaaatag ctgatatagg aacggaccac ggatacatac
    34021 cagtatattt gttaaaagag ggaaaagtac catttgcagt gctagcggat gttaataaag
    34081 gacctcttga caatgcacat aaagaagtca tacagaacaa tcttttagat aaagttgatt
    34141 tacgattggg ttctggtata gagatacttg aaatagggga agtagaagaa gtgataattg
    34201 ctggtatggg tggaatcttg ataagtgagc ttctcgaagc taaaaaagaa gtagcacata
    34261 atgtagaaaa attaatatta cagccaatgc aagcacaaga agaacttaga tattaccttt
    34321 taaacaacgg atatgaaatt ttagaagaag ttttagtgag agaagatttt agaatatatg
    34381 agataattgt tgccaaatat acaggtaaaa atactataat agaagatgag atatattatg
    34441 aggttggaat aaagctttta gaaaacaaag attctctttt taatgatttt atagaaaaaa
    34501 agataaagac atatagttct atagttaata aattagaagg gaaaaatggg gaagctatag
    34561 ataagaagag aaaggaaagc gaagttgcaa taaaaaaact tgaaaattta ataaaataaa
    34621 taggaggtat atatgctatt aaagagtcta actagaaaaa ttgaaaaaaa gtatcctcta
    34681 aacttagcag aggattggga taatgtaggt cttatagttg gagattttga tatggatgta
    34741 aaaaaggtat tggtatcttt agaagctaat gaagatgtta ttgatgaagc tatatccaaa
    34801 aatatagatt taattgtgac acatcatcct tttatatttg ggaaaattaa taaaattaat
    34861 agtggagatt taaaaggcag acttatccaa aaacttatta aaaatgatat atcactttat
    34921 tctatgcata cgaattttga tatagcattt gatggtctaa atgactattt tatggaaatt
    34981 atggaatttg gtaattcaaa ggttttagat ataactaaaa gcgaaaattt gtataaatta
    35041 gcagtatacg ttccacataa ctattcagat gaacttagaa aggttttaag taattcagga
    35101 gcaggtcata tagggaatta tagtgattgt acgttttcaa cagaaggtga aggacaattt
    35161 aagccattag aaggctctaa tccgtttctt ggaagtgtaa atgatataga aactgtaaat
    35221 gaagttaaaa ttgaaactgt agtaccacag aagcttttag gtggggtaat aagttctatg
    35281 ttagatgcac atccttatga agaagttgca tatgatttgt acaagttaga aaataaaggt
    35341 gagatatttg gactaggtag aataagtaaa cttgataaaa gtatgacatt agaaagtctt
    35401 tcaaggaaaa taaaagagaa attaaatatg aaacacataa gagtagttgg aaaccttagt
    35461 acagacataa cgaaagtagc cgttgtaaca ggagctggtt cagaatttgt aaaaaaagct
    35521 aagagacaag gtgcagaagt actaattacg ggtgatgtaa agtatcatga ggcacaagat
    35581 gcacttgata ttggaatgtg tatagtggat tgtggtcatt ttgatacaga agatatattc
    35641 aaaaatgtta tgaagagatt tttagatgaa tttagtgaaa ttgaagtaat aaagagtaat
    35701 gtatatttga atccatttag tactatttag cagtgtttga taataaaaat actatataaa
    35761 aaataaattt gagtttaatt agggggataa tgatgaaagt agcagtaatt tttcatagtg
    35821 tttgtgggag tacatattta ttagctagag aatataaaga agcgcttgaa gaaatgaata
    35881 tcgaggtaga tatatttaga gtaagtgacg aagttgcaaa aacacttcct caatattatt
    35941 tgataaattc caaagaatac aaagacgaat ttgaaagtat aaatgtaatt aaatctggaa
    36001 aagaaatatt agattatgat gctatattta tgggttcacc aacatattat ggaaatgtat
    36061 ctggaccaat gaagatgttt atggatagtt tttctgatat ttgggtaggt gctcctttga
    36121 gtggtaaaat atttggttgt tttgctacag caggttcaca acatggagga ggagaattag
    36181 ctttgcaagc tatgaatata tttgcccaac atatgggaat gactcttttg tcagttccat
    36241 gttcagtaag aggaggttat ccagcgtatg gaatacttca tatagcagga gataattctg
    36301 atataaggcc aaatgatgat gccaagatag gtataagaga ttacctaaaa agacttaaca
    36361 tataagaata tcatataaaa atacctaaaa gcgactgtat atacttttag gtatttttac
    36421 ttaattataa acgtgaagct ttaccagaaa tatggtcaat ttctatttta acaacagttg
    36481 ttaagttcat atccttctct atgtacttca tgccttcttc aaagaatcct ttagaatatt
    36541 tttttattat ttctacaaga gcatttttct tttcttcatt ttctacagtg caagcttttc
    36601 caaaaactat agcactagaa taagtagtac taaatttatc tggaataaca ctttcattag
    36661 caactactaa aaaagaaact ttgttgtttt tcgatatatt atctaactta tgcccatttc
    36721 ttgcacaatg aaagtaaata gaatcattaa agtatacata atttacagca actccataag
    36781 gataaccatt ttcagatata gtggaaaaag taccaaattc accatttttt aatacttcaa
    36841 cagtatcttc ttttgtcatt tctctttttt tcaatctcat ttctttaaac ataatatcat
    36901 cctttctaat tttgatgctt aaattaaatt ttagaacatt tataaagatt atgctatgtt
    36961 ttttacaaat tttaagaaaa aaatatagtt taagataaaa ggtagtgaaa gagaagctat
    37021 ttggaggttt atttatgata ttattgttag agtagtacaa ataatactaa taaatttaat
    37081 agctggtttc ttgttattta aggtagtaag catgtctata agaaggggaa gttatcgagg
    37141 gtagaagttg ttgtttataa cgatattata aagaaaatat tattatataa aataataaat
    37201 agtaaagagg tatcaagttg aatataatac ttaatacctc ttcaaaatta agttataaaa
    37261 gtgttgtggg aattgtccta tacatggtaa ggagataata aagaatgtat ctttaaagtc
    37321 tcaactaaac agcaaaattt atccaacaaa catacaataa atgcttcttt gtatctaggt
    37381 ggcttaacag taagtggcca catgtgtttt aaaattatgt ccgtttcttt ttcatttatt
    37441 tgaaaaaata aagttgcatt ttttaatgct tctctagggt gagtaaatcc atgtaatcct
    37501 tttctatcac ctttgtaatg ccaatcataa agaaaaaagt cgtgtagtaa agctcctcta
    37561 ataacacttt gaatatcaac acttaagtgc aattttttac ataatagata actataatat
    37621 gctactgaca aactatgttc aagacatgaa acattgccat gatgaggaaa tgttctcata
    37681 agttgaactt tttcagaaga aagtatctca gaagcacatt cattaaaata tttgatttca
    37741 gcttttgaca acattatgaa aatctccatt cttagtaata tataaatact atacttcaac
    37801 gataatatga aatatttctt atcctacaaa atataatacc caataataca agtaagatac
    37861 cttttatggt attttaaagt aagagagatt ttattaggct aaacaatgaa aaaattaaaa
    37921 gtaaagctat agcaatatat agtatttttc caagaggatt gccaaaattt atagtccatc
    37981 caataccaaa ccttttatta accattaatg atgggtcatt tggattatta tacatgatgc
    38041 ctgctatcca atacttctca tcttcttctg gagaataaga tgagttgaat tttaaatttg
    38101 gggaattaat atatgttgct attaaataaa ttataactaa aagcgttgta atattcatag
    38161 cagttaatag ttttgttttt attgataaaa gagtagtaaa aaactgtgtt gtcattataa
    38221 tcatcaatat taaaaacaaa taaccaattt tatttaaata tttaatgttt tcaactctac
    38281 tttcttcaat tctatttgta tctatcttaa tccttgactt tatggatcca atggaagtta
    38341 tatataataa aaccattaaa caaaagtcag taccgattaa tttaaataca ttaagaaatg
    38401 atttatctat aaaaacatca ggagacccat ttatgttcca atgagtggca attgagtctg
    38461 gcaattgatt ataattaaat gctataaaaa tactcattcc caaagtaaat agtatcggta
    38521 ttaaatagat tattttaaat ttttttatta ttttattttt cttatttata aaatccatat
    38581 ctactattaa ttttgaatct atatctatat gacctaattt agcataaatt tctgatttaa
    38641 gcttcttagc ttttttatgt gtatgaatat atagtatact ttcatataat aaaaaaccta
    38701 taataccaat aaaataggaa agttccaatt tattaaatgt aaagaccaga ataaaaacta
    38761 atataaagtc tataataaaa cctaaagata atagtttttt aaattcttta tctaacttta
    38821 taaagtaatt ataattttta tgctcttggt ctatagaaac tccatagatg tgttttttac
    38881 ctacaaaata gggtataaaa taaaatgtag catacatcaa aattagaact ggaaatattg
    38941 taaatagaca ttcaatctta ctcataatat ttcacctcat acttgtcaaa taaacttgaa
    39001 cttagtgaca aaaattcttc tttactaata cctgataaat aagattttgc caccaataat
    39061 tccaagtcaa gtttattttt ttgacgagtt gtattatcta ttttcattgg tagttgagct
    39121 acaatagcac cttttcttct atcaatattt aagaatccct cttcttttaa ttcattgtag
    39181 gatttgttca ctgtatgtaa atttacacca atattttcag ccatacttct tacagatgga
    39241 agtgattcat ttattttcaa ttctcctgaa gctatagcct tagttatttc ttctttaatt
    39301 tgtacataaa tagatttatc actattaaaa tctaaattta aaaccataaa aaacctccat
    39361 tatgctttat aaatgaaaac gattgttata tacatagtat aacataaaaa ataataacaa
    39421 acacaaaata taagtttata ttttgtaaaa attgtaattt aaaaaataac ataattttta
    39481 ttaaaataat acagatacta tttatagata gaaataaaaa ttagaaagga gaaaaaatat
    39541 gttaacatat ttaatgaaaa gacaaatgca taaaaaagat gatggaatga gtaaaccaat
    39601 gatgattaca ggagctgtaa ttacaggtgt aggagcatat gctgtatata aaatggtaaa
    39661 aagccataaa tctaattctc aaatggtcaa tacaaattat tatggaaata gcgattatga
    39721 tgattataaa tatgacgaat ttgattatga ctgtgattgt agagacacaa aacaagatta
    39781 tgaatatgaa gaattaaaaa aaaaagtaaa agaatttaat tcaagaagaa taaattgtga
    39841 aaattgtcca catgtttctc aagaagaaat gatgcaatat gtaaatagtg ttaaagatgt
    39901 aaaggaagag cttgatttac atgaagatgc taaaaaagat aatatttaca aagaagatga
    39961 atacaaaaaa tatgaagaag aataagtaat attttgtata actgaacaaa tagtaatgtc
    40021 aaattattta atatctagtt ttaatatgta agttgtaact taacttgaaa gaatcagtat
    40081 cattctttag atagttaagt aacaacttac attttatttt tataaatttt aatagttctt
    40141 tgtgactatt ttgtaatttt agaaatattt tagtatccag ggtaattgtg tataataaaa
    40201 cttgtataga tagatagtat gaaattaagc agatagttta aaattaaaat gaaaagaaag
    40261 gaaatagtta tgttaaagtt gttgatagtt gaagatgata gtactatatc ttttggaata
    40321 aagtatgctt tagaacaaga aggatttagt atagatatat caaaggattt atctagtgga
    40381 aaagaaatga tttcttctaa tgaatatagc atgatactgt tggatgttac attgccagat
    40441 ggaactggtt atgagctttg tcaatatata agaggattct ctcaggttcc tataatattc
    40501 ttgactgctt gtgatgaaga agtaaatatt gtaatgggtc tcgatatagg tggagatgat
    40561 tatataacaa aaccttttag aattagagaa ttaatatcca gaataaaagc tgttttaaga
    40621 agaaaaggta atacttcaga agaaaataag aaaatactta aatttggaga tttaagtata
    40681 tatacattag aagctagagt atataaaaat gataaagaaa tatttctgac atcagttgaa
    40741 tataaacttc ttttaattct tatacagaat aaaaatactg ttttaagtag aactcaaata
    40801 ttggaaaaac tttgggatgt aacttatgat tttgtaaacg acaatactct aactgtttat
    40861 ataaaaaggc ttagagaaaa aataggtgat gatttatgtg aaccaatcta catagaaact
    40921 gtaaggggga ttggttataa atggatagga agtgaaaata gtgtttctat ataatccaga
    40981 agtgaagaag tttttaagta agtatgttac tttgatgttt attgttatca taatatctat
    41041 tggatttagc ataatcaacg tgtccttaac taaagagatg gttgtaagaa ataatcaggc
    41101 tataatagga actttatcaa gcaagtatcc aaacttagaa agtcagatag tagacataat
    41161 aactcaaggg aagtctatgg agaacataga ttatggtcag aaaatattaa ttaagtataa
    41221 ttatgataaa tctattagga taaactctga gcctattatt tctaaattag ttttagagac
    41281 tatcaaaata aatataatat tagtatgtat aatatttatt ttgatatttg tgttgattgt
    41341 tagatatttt acgtcaattt acaatgattt atcagatatg actaagtatg tttactatag
    41401 ttcagagggt aagccatttg atatgaaaaa caagaatcaa gaagggcaga taggtcttct
    41461 aaaaactgaa ctcttaaaaa tgacgacaat tcttaatgaa aaggttgaac ttttaaaaag
    41521 agaaaagata tttttaaaca atacaatttc cgatatatca catcaattaa aaactcctat
    41581 gacttcttta ataatgttga atgatttatt atataatgat gtaccatacg aagtaaaaat
    41641 cgatttttta aataagataa aaaatcaatt aaatagaatg gattggttga ttaaaagcat
    41701 gcttaaatta tcaaaggtag aagcaaaagt gataaatttt aaaaaagata aggtaaaatt
    41761 tagtgaactc atacatagag caatgctatc tatgaaaata cctatggaga ttaaaaatca
    41821 aaaactgact atagagggaa atgataatgt atcttatatt ggtgatattg attggtccgt
    41881 ggaagcatta gtgaatataa tcaaaaattg tgtagaacat actcctgaat ttggaaatat
    41941 aattataacc tataaagaaa atccattatt ttctgaacta ataataaaag atgagggtga
    42001 aggtatagat aaaaaagata taccacatgt atttaaacga ttctatagag gaagaagtag
    42061 ttcaaaagaa gatagtgtag gaataggtct tgcaatgtca aaatctataa tagaaagcca
    42121 aaatggcgat atatatgtaa acagcgaaaa aggtaagggt acagaatttc atataatatt
    42181 tcataaaatg tatgatagtg actaatctgt aatatttaat tcactttata gtaatagcca
    42241 aaacctaata tatgaagtat agaatataaa tattggaggt agttatggaa attttaagag
    42301 tagaaaatct aactaaaagt tatggtaaaa atgaaacaaa agttgatgct ataaaaaatg
    42361 taagtttatc agttgaaaaa ggaacgttta tagcaataac aggtccaagt ggaagtggta
    42421 aaagtacctt attacattta ttaggaggag ttgacagacc aactagtggt aaggtttata
    42481 taaatgatgt tgatatatat aatttaaaaa ctaaggattt ggcgatattt agaagaagaa
    42541 atataggtct tatatatcaa ttttacaact taattccagt cttaaatgtg aaggaaaaca
    42601 tattgcttcc agcagagctt gacaatagag atattgatag agaatatttt gatgatttaa
    42661 tgaaaacatt aggtctaatt gatagagaaa agcaccttcc aaaccaagta tcaggaggtc
    42721 aacaacagag aacctctata ggacgtgcat taattaatag accttctata atattagcag
    42781 atgagccaac aggtaattta gatagtaaaa attcaaagga aatattagaa ttgttaaaat
    42841 tgtcagtaaa aaaatacaac cagacactaa taatgataac tcatgacaaa aatatggcac
    42901 ttcaagctga tagaattata agcatagaag atggaatcat aaaaagtgat gaggtgatgt
    42961 agatgaattt atatacatca ctaactatta gatacttaaa acaaaataaa agaagaacca
    43021 ttgtaaccat aatcggtata atactttcaa cagctttaat ttgtggtata ggaaatatat
    43081 ttgaaagttt tatggattat caaatgagag aaactataaa gaatgatgga agtttccatg
    43141 ttacatttta tgatgtaaat agaaaaaatg tggaatatgt aacgaaatca gctgaaatag
    43201 aaaaacatgc atttaccaaa caacttggat attctaaatt agaaaatagt gaaaatgcta
    43261 tattaagtat aaagcaatat gataaaaatg caataaatgg atataaagtt tctataaaag
    43321 aaggtagatt tccagctaag gaaggagaaa ttgttttaag tgaaagtatt attaatctta
    43381 tagatgataa gttaaaaata ggagataaga taactttaaa agtaggggat atgtttgact
    43441 caagcaagaa aaagattgat agtatgacat ttcatgaagg tgattatata gcaaatgaaa
    43501 aagatagaac ttttaaagtt gttggtataa ttgaaaaacc tgggtttgaa cgttataatg
    43561 gaattgcaac agctatagcc tactttaatc ctatgaataa ttacaatgat acaattaatg
    43621 tatcagtagc agtaaaaaat cctaaagatg tgtataagat aagtaataaa ataagtaaaa
    43681 atatatattc aaataaagat aaagaagcag tttctgatat gataaaatac aatgaacatt
    43741 tattgaggtt acaaggtgct agtaagtatt caaatataaa tagctctata aagtctataa
    43801 ttatagcagt aactatttta gtaatcgtat gtacaattgc tacagtgtac aattccttta
    43861 gtatttctat aaatgaacga aaaaaacagt ttgggatatt aaattctata ggtgctacat
    43921 ctagtcaaat taaaagatta gtttttatag aaggtattat aattagttta attggtatac
    43981 caataggact aatatctgga acagtagcta tagacttatt gtttaaaatt ataaataagt
    44041 attttactga atcggttgtt actaagatga gtttgcagat agtgtataat ccaataataa
    44101 ttattgttag tataataata gttttgctta caatctttat atcaattcta ctacctgcaa
    44161 tatcggcttc taatatttct ccccttaatg tgattaaaaa tactggagag tataaagtgg
    44221 gcaaaatcaa aagctcaaga cttattaaaa tgatttttaa aactgaagga gtacttgcat
    44281 ataaaaatat taggagaaat agaaaaaaat ttataataac tcttttttct ttaatggtaa
    44341 gtataataat atttatatct tttagtggct ttacattact tttactaaga ggtgaagaaa
    44401 ttagaaattc tcaaagaaaa tatgatttgt atttaactgc aaagaacaca gctaggtctg
    44461 tagaggatac tataagtgaa ctagaagata ttgatgggat aaaaaacttt gaattggcaa
    44521 caggacaata tgtgtctata agagtaagtg aaaataaaat aaataaatcc aaggaagatt
    44581 taatcaggaa atattatcaa aaatataaga ttggagatag ttatgaatat gatttcagta
    44641 ataatgaatt aatttttcca ggagattttg cagtaaaaaa caaaataaat aacttagtac
    44701 agggctcttt taataaagag agagcaattg aagaaaatgg tgttatatta gttagaaaaa
    44761 gtgcaattga agaaaatggg aagaaaggtg tagtagaact taccaactat aaagtaggag
    44821 atacagtaaa ttgtgaatat cttgatgaaa atgccttaag taaaaaagta aaggtcaaga
    44881 ttcttgctat aactgacgaa gaacgtctag gtcttggtta tcaaaatatg gggttacaat
    44941 ttataactta tgatgaagtt gctaaaaatt taaatttaaa attaagtaaa agccttatat
    45001 ttattgattc aggaggaagc attaagacta agaaggaaat agaagctttg gcaaataaaa
    45061 ataattttaa cttttatgat gaaagtgcaa gcaatgaaag tgaaaaacaa gatttaaagg
    45121 ttattaaaat atttgtatat ggttttatag tagtgatatc tttagtgagt gttacaaata
    45181 ttctaaatac agtaagtaca agtataaatc taagaaaaag agaacttgca gtaatacaat
    45241 ctataggggt tactcctaaa ggatttagga aaatgatata tttagaaagt tttatatatg
    45301 gtatactgtc attgttgttt ggaataccaa ttagtattgg tataattcta attatgaata
    45361 aacttatttc aggtgtaatt gaattttctc cgattatacc gtggacagcc atagttatct
    45421 gtatagtaag tgtttttata ataactttta tagcagggta tataccaatg agtaaattaa
    45481 ataaagaaaa tataatagat aatataagaa gagaaagtat atagatataa aaataattct
    45541 taactatata aaatattatt aaaatcattt aagtggtata aaatattatt atatcactta
    45601 aataattttt tatttatata agaaatctaa taataaatta ctagaggtat ttaactattt
    45661 agaaagaatt ggtattatat aaagtaagag aatatataat aagaaagaat atttgatttt
    45721 attggaaaac aaaagaaaaa gaaggtgatt actatttctc atataactgc gaagaatatg
    45781 tataaaagtt tagaggaaag aataaacaag tttccacaag gtgctccacc atctgataca
    45841 ttatacaaaa tactaaatgt actatataca gaacaagagg cgaagttagt tgctcagctt
    45901 ccaataaagc ctttcagagt aaaaacagca gctaaaattt ggagtgtaag tgaaagtgaa
    45961 gcatatagag tattggataa acttgctagt aaggctctga tactagatat agaagataat
    46021 aaagggaaga aatatataat gcctcctcca atggctggtt tttttgagtt tgccatgatg
    46081 agaacgagac acgatataga ccaaaaactt ttggcagagc tttactatca atatatgaat
    46141 gtagaagaag attttatcaa agatttattt tattcaacag aaacgaagct tggaagagta
    46201 tacgttcaag aggaagtttt aactaatgat aatgaggtta gtattttaga ttatgaaagg
    46261 gctactcata taattgatga atcaactcat ataggtataa gtatgtgtta ctgtagacat
    46321 agaatgcaac atgttggaaa agcttgtgat gctcctatgg atatatgtat gacgtttgac
    46381 aatgtagcaa attctttaat aaataataaa tttgcaagac gtgtggataa aatagaatgt
    46441 aaagagctac ttcatcaagc atatgaacat aacttagttc aatgtggaga aaatgttagg
    46501 aaaggggtta cgtttatatg taattgctgt ggatgttgct gtgaagcaat ggtagcagct
    46561 aaaagatttg gaaatcttca tccagtacag acaacaagtt ttataccaaa tataaaccat
    46621 gaaaattgtg taaagtgtgg taaatgtata actgcatgtc caatagatgc gataagcaag
    46681 gttaaggaag atggtaaaga atatataaaa attgatgagg atagatgttt aggttgtgga
    46741 gtttgtgtta gaaattgcca taaaaatagc attatgttat taaagagaga tgaaaaaata
    46801 ataactccag caaattcagt acatagagca gttcttatgg caattgaaaa agggcagtta
    46861 caaaatttaa tttttgataa taatgctctg gctagtcata gagctatggg agctatactg
    46921 tcagctatat taaagcttga accagctaaa aagattttag ccagtaaaca attaaagtca
    46981 gtatatttag ataaattgtt aagtatgaat gataaataga aactaactta aaaaaggcaa
    47041 agttttagac ttatctatat cttaataaac ttatcattta atatttaaat ttaattttta
    47101 cacatataaa acttataact taaataaaaa aaggctatat tcaattaata ttacttgaat
    47161 acagcctttt ttagttatgt taagctattt cttttatttg cttaaatgag ttttcatttc
    47221 catttccacc aatttgtgtt acagatttaa atctcatagt tttaaatagt tctttttgat
    47281 tataatctag tgagtttcct actagcatta caggagattt agtttttcca gccaaaactc
    47341 caacagataa tccgtctatt aaatcatctt gtttattcat tccattttta gcaacatata
    47401 aattgtctat cttagaatcc ttgtaaaatt cttttattac ttttgcatta gtttcatttc
    47461 tagtgctacc tgatattctc tgtggatttt gaagtttact ttctatattt ttagaaactg
    47521 tatattctcc accgattaca taagatttat caatcttttt gtttttaaac aagttattta
    47581 tttcagttat attactattt tcattagtaa gtattatagg catatcattt tgagctgata
    47641 cagctccaat gcttactgca tcggctaatc ctttttcgcc attaactact gaaatctttg
    47701 atatattgct aatattgttc aattctttag caatgttcat agaagtttga tatctatcac
    47761 ttcctgaaat tctagataca gagatattgt ttgattttat agtatctaaa gatttttcat
    47821 ttatagaagc ttctccacca actacatata catttttaac ttttaatctc tttaattcag
    47881 ccaaagtttt ttcatttatt tgagagcttc cagtcaataa tataggagcg tttttcttgt
    47941 atgcaaatgg tgttgcagcc aaagcatctg caattgctga atcgtttatt aaaactgcat
    48001 tttcagcatt ttcccaacct gcttgactta tcttaataga agtttcatat ctatcagttc
    48061 ctgtaagtgc acttgcattt acttcatctt gatatgtaac ctcaaatcta gcatttggac
    48121 ttcctaagaa aacaattacg cctccttttg gcaatctaac tctattgttc tttgtaacta
    48181 aagaatagtt tacaggaaca cctttatcat cataaacagc aaaagctgaa ttttgaggaa
    48241 gattaacttc tattttttta tttgcgatat cgtcaccaat cttataccat tttgcataac
    48301 cattggattc tagttcacaa gtaaaagatt tttctgctgg caaattagtt atagaatctt
    48361 cactaacata cgttagtgtt ccaaaagata aatactctgt accattttct ttatgaagtt
    48421 taatgtcgga taaatcacga cctattacac caggtatttc tataaaagca tttgagttat
    48481 tctcatccat tattttagtg ttaactatat aacctggagt ttcatcagaa agagcaagag
    48541 ttgccttcac agaaccaaac atatagcttt gagaagtata tttttcatct actagatagt
    48601 aatctttacc atttcttttt ttccatgctt cttttacact atttgatata ttgttgtcat
    48661 ctatcttttg agctacatag tataaacttg ctgtctgacc taatccaggg acatcatcat
    48721 aagagctcat atttaaatat gtgatattgt ttttttcttt tacaaatttt agacagctgt
    48781 tacctttttc agatacaaat ctatcttgac ctatgtatac gtatttatct tcaggtccat
    48841 tttctatata aggagaagat actgttaaag taccattatc attaacatct acttttatca
    48901 tatttgaaga agcataaaga ccactatttt cttttagaga gctaggcatt ttaacttgtt
    48961 gtggtttact aaatgtttta tcaggtttta tttctttaat tttacctttt tcttttaatg
    49021 cagatagtaa gatttcttgt ccaattattt cattaagttg actacttcca ccagaagaaa
    49081 gaactgcaac tgccatattt tcatctggaa gaactataag attactgtgg aataataaag
    49141 agtctccacc ttttgtaaga gcttttaaat tatactgatt aaatggataa gtgttgacac
    49201 aatcccaccc taaaccatat ccaagtatag agtcttctcc ttcaggccat agaccattta
    49261 aatattcttt gttttccata gcttttactg aagcaggaga aagaatacca tttgaatttt
    49321 tcataaatgt ttgtgcaaat gtacatagat tttctgcact tgaatataaa ccacctgcac
    49381 ctatagcatt aaggttatct tgcggaactg catcttccca ataaggcacg tatgcttttg
    49441 ctagttttga actatcaaaa ctattttctg tagtttttgt attttgtaag ttaagtggat
    49501 tatttatgta tttatcaaga aaattagtaa atgacatacc agatactctt tctactaaaa
    49561 tttcagctaa agtaaatcca tcattacaat aaacggaaaa agctcctggt ttagctttta
    49621 atctttgttt ttgtaattct tttaagaaat tatcatgacc ataagaatca ttgtctgcta
    49681 ataaaatagt gtttttaaaa ctacttccca tcaaccctga tgaatgattt aataacattc
    49741 ttggagtgat ttccttgtat ctatcatcag ccattttaaa ttcaggtata tactttacaa
    49801 caggagtatc taaatttaat tttccatcat caaccaactt cataacagct gttgtagtaa
    49861 acattttact gatagatgcg atactataca tattatcctt atttaagttt ttgttatcct
    49921 gtttgctgta aactccacca ttaccagaaa tctcaatttt gccattatca atcaaagcat
    49981 attgagcact tacagcacca tactttgata gcaaagtttg gattttctct ttagcaagag
    50041 ctttagtttt tgtgtaagat tccgcgtttt tactataatc atgtaattct atatcagaac
    50101 tttgatattt ttcggaatta tcttttgtat tatcagcaaa agtaatattt ggagcagcag
    50161 taaataacat actcaatact aatgtactag ataataattt agagagcctt tgcttaaaca
    50221 tattacatta cctctttccc tttttaataa tttataatta gcataacatt cttaattatt
    50281 ttaatcaaca gattattatc aataaaaaaa gcttttataa gtatagcttt ttatataaca
    50341 gagaaaaata taaaaataat atttgttgtt gtataaagaa taaagggtat aggtaatata
    50401 taaataaaat ggaggaattt tagacaatgt ataagaatat aaataaaaag caacttaaag
    50461 aaatgatgaa aaatgaaaag gatgttttat tattagatgt aagaactaaa gatgaattta
    50521 aggaatataa aatagaaaat gctataaata tatctttaca agagttaatc aataatatag
    50581 atgaaattta cgattataaa gataagaaag tagtagttta ttgcagaagt ggtcatagaa
    50641 gtgttactgc atgtaatttg ttagctgaag aaggttttga gcatttatat aatttaaatt
    50701 caggaataat tgattatatg agttaaataa tgtaagttat acattaaata ctatgtatag
    50761 ctctgcttat taagtaggaa tatatctaaa tatttataag ataaatttag gaaagaacga
    50821 attttttcgt ttttttctat gacagttttt gtagtaaata ttagttttta agttggaaaa
    50881 aggtagtagc tttttagcta ctacctttta atatgaactt agaatattat taaaaaaaat
    50941 atatttaaag acagaattaa ttttttaatg accagttaaa ttactatcgc cgaatttatc
    51001 attaaatggt tttataactc tatttatagg tccttttaga agtacattta aacaaataga
    51061 cagaatcata aatagtaata gaactagtat atctttagtt agatttggag catatatacc
    51121 accaactgct tcccttgtag cacctattgc ataggtaaat ggcattatag ggtttattct
    51181 ttggaagaat gtaggtgtaa cctgtatagg gaatgtacca ccagaagaac caatctgaac
    51241 gactaatagt actattgcaa ttgcttttcc tacatttcca aatacagaaa ctaaagaata
    51301 cactataaag ttaaatacca tactagtaaa cataagcaga actatcaata aaattggatg
    51361 ttttgctgtt actcctaaca ataatatatc tccagttcct attataaaac cttggacaag
    51421 agctatactt aaaaaagtaa ggcctcttcc aaagtaaatt tcataaggtt tatagtttcc
    51481 atgtacagat gtagacaata gtgctgaaat aagtaatata ccaacccatg tagaaagaac
    51541 actataaaat ggtgtcattg cagaaccata attttcaatt ggatataatt tctctgtttt
    51601 cacctcaaca ggttctttta agaaattaga ctttgtcaat atatcacttt caagcaagct
    51661 gactaatttt ttcatatctt caccattact aattttgctt aaagtatcaa tcaaatcatc
    51721 caacattcct tttgctaaag gaagtctttc tcttatcaat gatatacttt cctgtgcatt
    51781 tcctgaaagt tttagagaag tagtaagtat ttcttcaacc tttggaagtt ttgcttctgc
    51841 cttatctaaa acagtaatta tatcatttgc tacttttata ctgtttgcaa atatactatt
    51901 tataggtttt gatatttttg agtcaaaatt atttaaaata tttaaattaa ttcttccaat
    51961 accatttgat agacttaaaa cattattcaa agcacttata gatggttgtt gtccagatat
    52021 aactttgttt ttaatatcat ttaatgttga tatagatgaa tctattttat tgctagagtc
    52081 ttcaagatta tctattacat catccaatct attatttgat gtaagttggt ttaatttagt
    52141 taaaaagtcc accaaagtat cgtttaaaga ttgcaaatta gaaagttttt ctgataaatt
    52201 atctatcaac ttaggtacat cttcactgcc actatttact gcatcaatta aatttaatgt
    52261 aagagaagaa gcagaagatg aaaggtcaac cattaaattt aagtcagact taataagagg
    52321 agaaagttcg tctaaattat catttgtatc ctctaagaat ttttttaagt cacttgataa
    52381 tagttttgta tcattcagag tctttttaat tgtaggtaaa tcagatttaa tatctttaac
    52441 tgtatcagat aattttgaag tagcatcaga agctaaatca acagtcttat ttatatggtc
    52501 aaatctcttt tgaaggtcaa taagggaatt ttcaactttt gtcaattttg gaagactgtg
    52561 ttcaattcct gcaccaactc cgtttgatat accaagaacg atttcactaa ctgtttttac
    52621 tatagtctga ttaacctgta gttgtattgt agaagcacct ttatctgtaa tctttggtgc
    52681 aactgcattt attttttcat taacagtata gataatttcg ccttttttaa catcatctgt
    52741 aattaaagat gtcaaatctt ttgtaaaatt ttttggaatc ttaagtgatg cataataagt
    52801 acctttttta acaccttcaa gagcagtttt ttcatctaca aactgccaac ctaaactctt
    52861 gttatctttg agttgttcaa ttaattggtc tcctacatta atcttttgtc ctgctatttc
    52921 atttccttta tcttcatttg ttactgctac aagcatatta gcagtgcttc cataagggtc
    52981 ccaagatgcc tttatattga accaagcata cagagatggt aaaaaagcaa gacctaaaac
    53041 tattacaagt acggcataat tgccacgtat atcttttagg tcacttttaa aaatttctaa
    53101 tatatttttt aaaccctttg aaggtcttaa attcttgata ttattccagt ttaaaatttc
    53161 ttttaaacta ttagtttttt tcaaatgtct cacctcctaa aatattttga taaagaaaaa
    53221 agttagattt ataatcaatt ttaaattata ttacttttta cacaaatagt aaagtta
//
LOCUS       DAYAOO010000019        53215 bp    DNA     linear   BCT 12-OCT-2024
DEFINITION  TPA_asm: Clostridioides difficile isolate ST8-SSI-h139-18
            SAMN40601845-rid21577343.denovo.019, whole genome shotgun sequence.
ACCESSION   DAYAOO010000019 DAYAOO010000000
VERSION     DAYAOO010000019.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN40601845
            Sequence Read Archive: SRR28438827
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 53215)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 53215)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-MAY-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-MAY-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002157583.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002157583.1
            Genome Coverage       :: 163x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/11/2024 16:19:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 4,038
            CDSs (total)                      :: 3,963
            Genes (coding)                    :: 3,930
            CDSs (with protein)               :: 3,930
            Genes (RNA)                       :: 75
            rRNAs                             :: 6, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 60
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 33
            CDSs (without protein)            :: 33
            Pseudo Genes (ambiguous residues) :: 0 of 33
            Pseudo Genes (frameshifted)       :: 7 of 33
            Pseudo Genes (incomplete)         :: 25 of 33
            Pseudo Genes (internal stop)      :: 11 of 33
            Pseudo Genes (multiple problems)  :: 8 of 33
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..53215
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN40601845-rid21577343.denovo.019"
                     /isolate="ST8-SSI-h139-18"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Denmark"
                     /collection_date="2018"
                     /collected_by="Statens Serum Institute"
     gene            232..1425
                     /locus_tag="ACGI5H_001255"
     CDS             232..1425
                     /locus_tag="ACGI5H_001255"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428474.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FprA family A-type flavoprotein"
                     /protein_id="HFG9696968.1"
                     /translation="MSKVFEVKKDIYFTGVVDEGLKVFDIIMETEFGTTYNSYLIKDE
                     KTVLFDTVKANFKDEFLSNLSEVTDIAKIDYVVIHHTEPDHAGSLKYLLDINPNIEVY
                     CTKAAKLYLDGQINRPFNCHVIKDGEILNIGKRNLRFITAPFLHWVDTMFTYIEEDKT
                     LLTCDAFGCHFASVDAEVVNSEDYLKSAKHYYDCIVKPFAKHVLSAVDKVVGLNIEFD
                     TILTSHGPMLTKDPMAAVKRYVEWSTEAVNTTNQNQVSIFYLSAYSNTLEMAKKIKEG
                     LDKEGAKAELYDLEDMTLTEMHDTLVVSKVILLGSPTINKTMVKPMWDLFSVIDPMAN
                     QGKIAGVFGSFGWSGEGITMAETLLKSMSFKMPVESLKKKFFPSEETLKECMAFGAEF
                     AKLVK"
     gene            complement(1637..2457)
                     /locus_tag="ACGI5H_001256"
                     /pseudo
     CDS             complement(1637..2457)
                     /locus_tag="ACGI5H_001256"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428476.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transglutaminase domain-containing protein"
     gene            complement(2587..3378)
                     /locus_tag="ACGI5H_001257"
     CDS             complement(2587..3378)
                     /locus_tag="ACGI5H_001257"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419065.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="permease prefix domain 1-containing protein"
                     /protein_id="HFG9696969.1"
                     /translation="MKLIDEYLDKLYKKCDNKSTIELKQEMRCHLIESANEFKLEGLD
                     EEEACKKAIERFDDGDEMQYELCNIIKELSLSLDRHKSIVMGFKKVLGYISIIAFLIS
                     GFMWYYNNSLQHNMYNLGKELDGEIKQLAERHDMTKIGEYKLELEKILDKDKYSKVKA
                     LRLYVIDMKDGNTNLSSSGLNANMVYEREADYNNISNFIQHLGYNGKDFLDKNGNIVN
                     PDIFLEYFFYFESEMLIPVAFVFGLLCIIAYFILRFKISLIKNNN"
     gene            complement(3382..3711)
                     /locus_tag="ACGI5H_001258"
     CDS             complement(3382..3711)
                     /locus_tag="ACGI5H_001258"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419063.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PadR family transcriptional regulator"
                     /protein_id="HFG9696970.1"
                     /translation="MQLNKEVLKGYIDILIVSILEKKDCYGYEIAKQVRERSEFELKE
                     GTMYLALKRMESKNLIKSYYSNEQSSGGRRKYYNLTNEGKDFLEIKKQEWRFIKKVMN
                     QFLGEVD"
     gene            complement(4196..4609)
                     /locus_tag="ACGI5H_001259"
     CDS             complement(4196..4609)
                     /locus_tag="ACGI5H_001259"
                     /EC_number="4.2.3.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008929 - methylglyoxal synthase activity
                     [Evidence IEA];
                     GO_process: GO:0019242 - methylglyoxal biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="methylglyoxal synthase"
                     /protein_id="HFG9696971.1"
                     /translation="MNIALVAHDQMKNTMVGFCIGYESILKKYGLYATGTTGKRIMDE
                     TELNINRLASGPLGGDQQIGSLIVTQEIDLVIFLRDPLTSQAHETDIQALIRLCDVYH
                     VPIATNLASAEIFIKALDRGELSWREVRKSKSQRI"
     gene            complement(4650..5780)
                     /gene="rodA"
                     /locus_tag="ACGI5H_001260"
     CDS             complement(4650..5780)
                     /gene="rodA"
                     /locus_tag="ACGI5H_001260"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905338.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_process: GO:0008360 - regulation of cell shape
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="rod shape-determining protein RodA"
                     /protein_id="HFG9696972.1"
                     /translation="MKKININYKSTIKLIKQLDWKLIVTVLAIFIFGLVILSSATHAN
                     STGSYNQLIKQGLAFVLGIGMIIVILFFDYNLLGRYYKALYIISLILLAIVLLPGIGT
                     VKGGARSWINLGPLDLQTSEIVKLTFVLSYAKILESKKDKLNTLKEVMPVVVYSLPFI
                     GLLIAQPDLGTGIVFCCMIFAMLFTAGLSSKLIKRGIIILLVSMPLMYLMMADHQKVR
                     IEAFLNPEDVTLKGNYQVMQSLIAIGSGGVTGKGLYNGSQNQEDFLPVQDSDFIFAVV
                     GEELGVIGMAVLIILFMIFLLRLLAIARDAKDFYGTLIVVGVMGMFGYQIIQNIGMTV
                     ALIPVTGVTLPFVSYGGSSLLTSLANLGLVLNVCMRRKKINF"
     gene            complement(5865..6149)
                     /gene="minE"
                     /locus_tag="ACGI5H_001261"
     CDS             complement(5865..6149)
                     /gene="minE"
                     /locus_tag="ACGI5H_001261"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419058.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0032955 - regulation of division septum
                     assembly [Evidence IEA];
                     GO_process: GO:0051301 - cell division [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cell division topological specificity factor
                     MinE"
                     /protein_id="HFG9696973.1"
                     /translation="MLDLFRVFSNEAKTSKSVAKERLKLVLVHDRVDCSPQLLEMIKT
                     DILKVIANYAEIEDDGLEIKMSKCRGEHDDKPVSALVANIPLKNIKDRCM"
     gene            complement(6167..6964)
                     /gene="minD"
                     /locus_tag="ACGI5H_001262"
     CDS             complement(6167..6964)
                     /gene="minD"
                     /locus_tag="ACGI5H_001262"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419057.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_process: GO:0000918 - division septum site selection
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="septum site-determining protein MinD"
                     /protein_id="HFG9696974.1"
                     /translation="MSEVIVITSGKGGVGKTTTAANLGTALSLENKKTVVVDADIGLR
                     NLDVVMGLENRIVYDIVDVVEGTCRLKQALIKDKRFDNLYLLPAAQTRDKNAVSVEQM
                     IDLCEKLKESFEYIIIDCPAGIEQGFKNAVAGADRAIVVTNPEISAVRDADRIIGLLE
                     ANEIKEIRLVINRIRNDMVKRGDMMDKQDIIEILAIDLLGLVPDDESIIISTNKGEPA
                     ILDSKSLAGQAYKNIAKRILNEEVPLLDLEVEDGFFGRLKKMFSMAK"
     gene            complement(6988..7671)
                     /gene="minC"
                     /locus_tag="ACGI5H_001263"
     CDS             complement(6988..7671)
                     /gene="minC"
                     /locus_tag="ACGI5H_001263"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419056.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0000917 - division septum assembly
                     [Evidence IEA];
                     GO_process: GO:0032955 - regulation of division septum
                     assembly [Evidence IEA];
                     GO_process: GO:0051302 - regulation of cell division
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="septum site-determining protein MinC"
                     /protein_id="HFG9696975.1"
                     /translation="MSLREICSQELVEFKGNKRGIIVNIKREAPFEEIQEKIINKLEA
                     YVGFFNGAKISKINSDCLTDMEILELKEGITSRFDVEFVEDQKIEENSNFPTKYVNTL
                     RSGENIEFEGDVVILNDMKPGSKVLSKSNTVVMGDINAGAKVVAGGNVFVMGKIEGFV
                     HAGAEGNEFAYVVAGNLNPKILQIADNIAEAPDDEENYESESEISPEIAFVSNGRIVI
                     ESYLSKLDK"
     gene            complement(7769..10747)
                     /locus_tag="ACGI5H_001264"
     CDS             complement(7769..10747)
                     /locus_tag="ACGI5H_001264"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896080.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008658 - penicillin binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-binding transpeptidase
                     domain-containing protein"
                     /protein_id="HFG9696976.1"
                     /translation="MEENKQVDRLKIIKIVMGVIFLAILVKIIYMTTFKYEYYNELAE
                     NKTYKKLAIEAPRGEIKDRYGRLLAGNKNLFTVQVSGNDINKKDANKHSRANEISLKL
                     INLLERNGEEYVDEFPIYVENGKYYYTYDRDIREYKSENGIPNDYNAKESFYYLVDKL
                     ISAGILSQEDKRLDATRLQAKLNENGYYPPILVSKWMFTAERDKRDWLASYKIKETKL
                     SAKEAFEKVRNSDALEIDKSLSDEDARKIMVVRDLIKSKGYSQYNPVTIAKDVGETTI
                     AQIEESAMDLVGVSIAVEPVRYYPNGSLASHMLGYVGKMPSTQIESYLQKGYETGDMV
                     GLAGVEKSNESRLRGTDGYKMVKVDALGRISKEIESKKPKSGDTVYLTLDKDLQEVSD
                     NALKQIIEVASKGGTFKSKFGDKPISAYAGKAQSAALIAIDVKNGEVLASSSYPNYDP
                     NKFAKGISTEDYKALQPKNPNDLLAGSPLLNLVTQGEFQPGSSFKMVTSMAALENGLD
                     PNFTINDPGVIMLGKKSFGDYVWNHGRGNHGMTNLYKAIQESCNIYMATIGTGKTWPD
                     GKSIGIDMNANKILEYAKLFGLDQNTGLQDEVEERAGKVPSTEDKLKSTQALLKSNLE
                     REMANDFVDITREKNPKEYEKRINEIVSWAAEKKTPGRVETMNRLKKLDVKEDRIEEV
                     ADLAVFSYFNFAKWSTADTFNLAIGQGENAYTLAQISRYVAAIANGGNLVELSVVDRA
                     VSSDYSSVKINDQKKVEKIPFKNPDNLKELTKGMKLVARQGTAKSAFADFPIDVAAKT
                     GTAEKSGKIPTDNEYEYLKSHMSSYNVNLNDAIKLADKMKAEKEKELSLAKEKEIKKK
                     LENKDLKDEERKKLEEELEDGVKVRLEDTDKVNSSYLRKAIKELNPKITDDQIDRFKQ
                     DYGSFTWTVAFAPADDPEIAVVCVIPQGDSSVFSLLPTREVIGTYMGLEPTNSKNDNK
                     TNDVNNSSDENINFESQINR"
     gene            complement(10759..11247)
                     /gene="mreD"
                     /locus_tag="ACGI5H_001265"
     CDS             complement(10759..11247)
                     /gene="mreD"
                     /locus_tag="ACGI5H_001265"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438053.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_process: GO:0008360 - regulation of cell shape
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="rod shape-determining protein MreD"
                     /protein_id="HFG9696977.1"
                     /translation="MKKVLLCLLGIVLMTIENSITNYIDIFGISFNLVLIYVTIISLY
                     LDELEGGIIAAIIGLIKDITVGGIFGVNALILFIIAYAIGYMRDQLYKGSYIITFVLI
                     FIGSLIDSIVNIGTSSIIYQSYNISTLFVKGLLVAPIVNSLIGLVIYRLSKRAVLKLK
                     ED"
     gene            complement(11262..12155)
                     /gene="mreC"
                     /locus_tag="ACGI5H_001266"
     CDS             complement(11262..12155)
                     /gene="mreC"
                     /locus_tag="ACGI5H_001266"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428482.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0008360 - regulation of cell shape
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="rod shape-determining protein MreC"
                     /protein_id="HFG9696978.1"
                     /translation="MALRFDKNKNEKKRINVKVIATGVVAITLIGIVGISIGKFSSGS
                     PVNLGVASDAITSVGKGINDGFSFIKNGFKDVANFKDNSKKVKKLEEENEKLKKNMIA
                     LNAKLDKTESLEELKKTLNFVQEEYKATSISASVVGKNDGNWYESFVIGAGKNSGVKK
                     ESIVMNGSGLVGIVYEVSNNYSKAISLLDSKASVSFKLAKDANAKGTITQNTTLDNKD
                     SYNSKGYLQGYMFDSSYNVIQGDIITTSGLGFFPDGIPIGEVEKVVDDKDKSLKYVVV
                     KPYVDFKNINDVVVIEPRNIG"
     gene            complement(12165..13226)
                     /locus_tag="ACGI5H_001267"
     CDS             complement(12165..13226)
                     /locus_tag="ACGI5H_001267"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419052.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0000902 - cell morphogenesis [Evidence
                     IEA];
                     GO_process: GO:0008360 - regulation of cell shape
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="rod shape-determining protein"
                     /protein_id="HFG9696979.1"
                     /translation="MAKEKKKEKKGFFSFNKMTKDMGIDLGTANTLVYIKGQGIVVRE
                     PSVVAIRDDSKEVLAVGEEAKKMIGRTPGNIVAIRPMKDGVIADFDITQSMISYFIQK
                     AADKKGVVSPRIAICVPFGVTEVEKRAIEEAARQAGAKDAFLIEEPMAAAIGAGLKVE
                     EPEGNMVVDIGGGTSEIAVISLGGIVTAKSIRIGGDEFDESIVAYVKKEYNLMIGERT
                     AENVKINIGSTFKDDEEINMQIRGRDLISGLPKTIEICSTEVREALKEPVSSIVDAIK
                     STLERTPPELASDIMENGIMLTGGGALLRGLDKLITQETGMSVQIAETPLDCVALGTG
                     KSVEDQEIFEKVLMMNTKN"
     gene            complement(13296..13955)
                     /gene="radC"
                     /locus_tag="ACGI5H_001268"
     CDS             complement(13296..13955)
                     /gene="radC"
                     /locus_tag="ACGI5H_001268"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RadC"
                     /protein_id="HFG9696980.1"
                     /translation="MAPEERPREKMLAKGVKSLSNAELLAILLRTGNKNKNAIELANY
                     IINRDIQGIRHLEDMTIEELCNIDGIGLSKSTQIKAALELGSRVASFKPIKYKIRNPW
                     DIQRYYMDSLRYLKKEVFKAVLLNTKNEIISDVDVSIGTLSSSLVHPREVFKEAIRRS
                     ASKIIVMHNHPSGSVEPSREDKNITSRLIKCGEIIGIEIIDHIIIGDGLYFSFKENMI
                     I"
     gene            complement(14000..14584)
                     /locus_tag="ACGI5H_001269"
     CDS             complement(14000..14584)
                     /locus_tag="ACGI5H_001269"
                     /EC_number="3.6.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428485.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0047429 - nucleoside triphosphate
                     diphosphatase activity [Evidence IEA];
                     GO_process: GO:0009117 - nucleotide metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside triphosphate pyrophosphatase"
                     /protein_id="HFG9696981.1"
                     /translation="MNIILASASPRRKEILENTNVRFDIIKNEIDEIILEGETPKHLV
                     MRLAFEKSMSVASEHNEDVVIGADTVVVLDNAILGKPKDESCARDMLKRLSGREHQVI
                     TGISLINLCEDKKVIDYVISNVKFKTLSEQDIEDYLKTNESFDKAGAYGIQGYGALLV
                     EEIRGDYFNIVGLPISRLGDLLKKYFSINLFYGV"
     gene            complement(14804..15775)
                     /locus_tag="ACGI5H_001270"
     CDS             complement(14804..15775)
                     /locus_tag="ACGI5H_001270"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419048.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0009055 - electron transfer activity
                     [Evidence IEA];
                     GO_function: GO:0051536 - iron-sulfur cluster binding
                     [Evidence IEA];
                     GO_process: GO:0022900 - electron transport chain
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="RnfABCDGE type electron transport complex
                     subunit B"
                     /protein_id="HFG9696982.1"
                     /translation="MVILTAVLVLGIMGLIFGIVLDFASKKFAVEVDERVEAILGVLP
                     GANCGGCGFPGCGGLANAIVEGNAPVNGCPVGGADVGAKVGEIMGISAEAGEKQVAKV
                     ICKGTCSSAKDKYEYEGISDCRAANVLNSGAKMCKFGCLGLGTCKDACKFDAISIVDG
                     IAVIDEEKCVNCGKCKEVCPKGIIITKPESQEVVVECNSKEFGKAVKEKCTAGCIGCG
                     MCVKACKFDAIIFEDKIAKIDPNKCVGCMQCVAKCPTKVISGDITKKKKVTIDQELCV
                     GCTVCKKQCKFDAIEGELKEKHKVDADKCVGCHLCMEKCPKKAIKIL"
     gene            complement(15791..16366)
                     /gene="rsxA"
                     /locus_tag="ACGI5H_001271"
     CDS             complement(15791..16366)
                     /gene="rsxA"
                     /locus_tag="ACGI5H_001271"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419046.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_process: GO:0022900 - electron transport chain
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="electron transport complex subunit RsxA"
                     /protein_id="HFG9696983.1"
                     /translation="MNLILLFLSIVLVNNVITSQFLGICPFLGVSKKVDTAVGMGVAV
                     TFVLTLASIITYFIQILLVKTGTGFLQTIAFILVIASIVQFVEMVIQKMSPSLYQALG
                     VYLPLITTNCAVLGIALVNVQKSYNLVETIINGFGAGAGFTLAIVIFAGIRERLELAD
                     IPEAFKGFPITLISAGLMSIAFLGFTGLIKL"
     gene            complement(16381..16974)
                     /locus_tag="ACGI5H_001272"
     CDS             complement(16381..16974)
                     /locus_tag="ACGI5H_001272"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419045.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_process: GO:0022900 - electron transport chain
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="RnfABCDGE type electron transport complex
                     subunit E"
                     /protein_id="HFG9696984.1"
                     /translation="MNLAKVFKNGLIDENPTFVQVIGMCPTLAVTTSAINGIGMGLST
                     AAVLICANLVISLIRKITPDKIRIPIFIVVIATFVTIVGMLLKAYVPALDKALGIYIP
                     LIVVNCLILARAESFAFKTGAMPSIVDGVGQGLGFTVALTIIGAVRELLGNGSLFGMT
                     LFGASFQPVLIFILPPGAFLTLGFLFAGFNKLRSKKA"
     gene            complement(16987..17556)
                     /locus_tag="ACGI5H_001273"
     CDS             complement(16987..17556)
                     /locus_tag="ACGI5H_001273"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902280.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_function: GO:0009055 - electron transfer activity
                     [Evidence IEA];
                     GO_function: GO:0010181 - FMN binding [Evidence IEA];
                     GO_process: GO:0022900 - electron transport chain
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="RnfABCDGE type electron transport complex
                     subunit G"
                     /protein_id="HFG9696985.1"
                     /translation="MNSMVRLGGTLLAISAIAALALGATNQVTAPVIEQRNIQANNEL
                     RKAVLPEAKEFKEMKEDTYKGLGDGLIAEVYEGLDGSEVVGYTLKAKPSGYGGEIEVM
                     VGISSEGQVTGVDIGNMSETAGLGAKAKDDAFKGQYKGKTAEPLEVAKGSTTADNQIL
                     AISGATITSTAVTTGVNAAIDVFNSALNK"
     gene            complement(17556..18533)
                     /locus_tag="ACGI5H_001274"
     CDS             complement(17556..18533)
                     /locus_tag="ACGI5H_001274"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419041.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_process: GO:0022900 - electron transport chain
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="RnfABCDGE type electron transport complex
                     subunit D"
                     /protein_id="HFG9696986.1"
                     /translation="MENKLIVSSSPHVRSNEDTSYIMKQVIIALLPAAVAGVYFFRLN
                     ALSAMFFCILGTVGTEFLYQKFTKQKSTIGDFSAVVTGLLLAFNVPASLPWWMCLVGG
                     IFAILVVKMVFGGIGCNFVNPALAARAFLLASFPVAMTAWTQPGVNWIGKNLDAVTTA
                     TPLSFLKNGAAGLADLSSNGISLADMMIGNIGGCIGETSAILLLLGGVYLMYKGIINY
                     VIPVFYIATVFILTFLLGGFNITFAIYQLFAGGLMLGGFFMLTDYTTSPMTKKGQIIY
                     AVLAGLITTVIRMYGGYPEGVSYSILLVNCLAPLIDKFVRNRVFGEVAK"
     gene            complement(18556..19893)
                     /gene="rsxC"
                     /locus_tag="ACGI5H_001275"
     CDS             complement(18556..19893)
                     /gene="rsxC"
                     /locus_tag="ACGI5H_001275"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419040.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0009055 - electron transfer activity
                     [Evidence IEA];
                     GO_function: GO:0051539 - 4 iron, 4 sulfur cluster binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="electron transport complex subunit RsxC"
                     /protein_id="HFG9696987.1"
                     /translation="MKLLTFKGGIHPPYRKEYSNTKALEKAQAPKIVYIPLQQHIGAP
                     AKPIVEVGDEVKFGQKIGEQQGFVSCNVHSSVSGKVIAIEQHEVPGGSAQCVVIENDF
                     KEELHESVQPKGQLEDLSKEDIVGIIKEAGIVGMGGATFPNHVKVSPPPDSKAEVVIL
                     NGAECEPYLTADHRLMVENPEDVVFGLRALMKVLDVKKGFIGIETNKPDAIEAIQNVA
                     KDYSEIEVVGLQVKYPQGAEKQLIYACTGKEVPSGGLPIAAGAVVDNVATAAQIAKSI
                     KTGMPLVERITTITGSCIKEPKNLITKVGTLVSEIIEQCGGFKEDKKIGKVIMGGPMM
                     GIAQYTTEIATNKGSSGILCLDEEESRTPDIQNCLRCGRCTDVCPSFLQPLFISAYSL
                     KDDYDTAEYHRAMDCIECGSCSFICPARRPLLQSIRSAKREIGAKRRKQAAQK"
     gene            complement(20109..21053)
                     /locus_tag="ACGI5H_001276"
     CDS             complement(20109..21053)
                     /locus_tag="ACGI5H_001276"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428490.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9696988.1"
                     /translation="MNRRKTIYRGFNNNRHKIDLRKYVITIACLCLIGYYSYTKIKDS
                     KILEYVSAKIPFLNNSSDITYKDISDELNSIKKGKKSKSQTNSDDKQETNPEKAVNNT
                     KEPEEVKLATIEGWDMYTIQVAAIDNNDDLKKIQTSLVNNDIPFSVMEKDGVKKIQTY
                     SSFDENDVRKQISSVRKVFPDAFLSHLDAPMLSLEYTSNYAYIESISKELNKLITNFK
                     EESSFWSNAENNVDMEKYNTILTNRKAISQNISKEAEKIDYSEMRLFKDNLIEYVKNV
                     NEKIDTASKAANEEKYSVSKSLLLSSMQEYSMFINSIK"
     gene            complement(21164..22438)
                     /locus_tag="ACGI5H_001277"
     CDS             complement(21164..22438)
                     /locus_tag="ACGI5H_001277"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729513.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SH3 domain-containing protein"
                     /protein_id="HFG9696989.1"
                     /translation="MKKAIAALGIGAVAVSVSSINASALEKGTVTASALNIRSGPSSD
                     CDKVAKLYKGKTVEILEKSNGWYKVRVSSSVVGWGSAKYISTSGSSEGTSSQNNPTSS
                     GTTISGNGKVNVSSRLNVRSGAGTNYSLVGKANNGDVVKLLEQSNGWYKIKLSNGVTG
                     WASSQYISKTSEDVGTNNSSNSNSTNNSDKKPSSEESIEGKNGKVTSAVSLNVRSGPG
                     TSYSIIGKLNGGDVVELKAKSNGWYKVKLSSGTIGWVSASYISETNEDTKEKPNSSSN
                     QNSQSNSNSKPSFTGNSDKSTAKGSTIVDFAYTLIGIPYQWGASGPDKFDCSGFTQYV
                     FKHSVGVSIPRVSREQANFGSAISMGNYAPGDLVYFDTDGDGTTNHVGIYVGNSKFIH
                     CSGTQTNPNKVKVDNLTSSYWSKVLLGARRFV"
     gene            complement(22570..22941)
                     /locus_tag="ACGI5H_001278"
     CDS             complement(22570..22941)
                     /locus_tag="ACGI5H_001278"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419037.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HFG9696990.1"
                     /translation="MKFNFCHNNFNVTNLEKSLDFYKKALGLKEVKRKEAEDGSFILV
                     YLGDGITSHTLELTWLRDWDRPYNLGDNEFHLALEVEEFDEAKKLHKDLDCICFENES
                     MGIYFIADPDNYWIEILPKNH"
     gene            complement(23169..23768)
                     /locus_tag="ACGI5H_001279"
     CDS             complement(23169..23768)
                     /locus_tag="ACGI5H_001279"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419035.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9696991.1"
                     /translation="MESRGYKEDLKKMILDMAHKELESYVSQKGAKKYFEGNLDKIIN
                     NNIKKFNQSIGLNRVYLKMLKKCAYQESVTSISRTIKKEALFKSKKELFAFSEYLKLD
                     INKRLSYNQILRKISRYIYYNRSSYAQKYVVFKRGDEEYLLEPEKIKDELISSYRSKT
                     REDMRSIAKLLDIEVEDDYNAEDIRKKVINYIIKEKLKS"
     gene            complement(23969..24181)
                     /locus_tag="ACGI5H_001280"
     CDS             complement(23969..24181)
                     /locus_tag="ACGI5H_001280"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419026.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="heavy-metal-associated domain-containing
                     protein"
                     /protein_id="HFG9696992.1"
                     /translation="MKKKLLVEGMSCGHCVNHLKTALTEDIDGIEVLDVDLENKCASV
                     DMKDDVSIEKLKEVIAELGFELKGIE"
     gene            complement(24254..25969)
                     /locus_tag="ACGI5H_001281"
     CDS             complement(24254..25969)
                     /locus_tag="ACGI5H_001281"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888909.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HFG9696993.1"
                     /translation="MKRIKVLTVVLAITLMVAGCSNTKTKQSSSDSSLQSQSSIDAKY
                     INLTMVTPKTINPITNTDKSVGYIMNLVYDSLFTIDENYNVIPQLVKEYNIAQDGMSI
                     DIKLKDAKWHDGKNVTSNDVNYTIGLIQKSADSPYNEFTKNIASVNIKSDKDFTIKFK
                     ARYAFSIDSLIFPIVSQNHLDSKDVNDKNNNMIGNGKYKIESYTEREGMVLSVNKDYY
                     EEVPKTMKNIKVGMVPNEDARTSMVMALDSDITNVTLNDLSKFQEKEFNITKYQGRDY
                     ECVLFNYNNPFFKDVNFRKAIAHSIDKDRIISEGYMDDATPVNFPLNSKSKYYNSEMK
                     DLEFNKDKAIECLAKVEYANVNSVNQNDNKVKNQKKSAKKNSKKLTPEEEAKVKKAEE
                     DRIKKEAEEKKNREKEEVKKSLSEMNLKIIVNRDNSERIKTANIINENLKAIGINSTV
                     NQLSDKDMENALNSKNYDLALVGWKLSIIPDASSIIASSGYTDDKLNGYMSALTSSTS
                     EIETKKAYKDVQTYIKDNATFISLAVRNNYIVSNSRLKGKITPNDFDVYEGISNLDIK
                     SNESN"
     gene            complement(25969..26523)
                     /locus_tag="ACGI5H_001282"
     CDS             complement(25969..26523)
                     /locus_tag="ACGI5H_001282"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438043.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lytic transglycosylase domain-containing
                     protein"
                     /protein_id="HFG9696994.1"
                     /translation="MNSKKVLILSIFIILFGALLMESKVIHKFLYPKKYSEYVEKYSK
                     EFNLDENIVYSVIKAESKFNSSAVSKKEAKGLMQILDITRDWGAEELNLKNVDIFDPE
                     TNIRLGCWYLSKLYKEFGKLDLVIAAYNGGSGNVKKWLENNEYSKDGENLHDIPFKQT
                     SKYVEKVKNNYEHYNKIYGKKGKN"
     gene            complement(26516..27118)
                     /gene="coaE"
                     /locus_tag="ACGI5H_001283"
     CDS             complement(26516..27118)
                     /gene="coaE"
                     /locus_tag="ACGI5H_001283"
                     /EC_number="2.7.1.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419019.1"
                     /note="Dephospho-CoA kinase (CoaE) performs the final step
                     in coenzyme A biosynthesis; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0004140 - dephospho-CoA kinase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0015937 - coenzyme A biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="dephospho-CoA kinase"
                     /protein_id="HFG9696995.1"
                     /translation="MLILGLTGGIGCGKSSLSNIFRNLNIPIVDADIISRKIFEDKLL
                     LEKVFVHFGQSIKNDDGTLNRKALGKIVFSDEEKLKELNNLTHPRIREKIISEIEKLR
                     KKGENIVVLDAAILVESGFLDMVDKLLVVTCKQEVQISRIQKRDNCSEQEALSRINSQ
                     MSQEEKSKYGDYIIDNSGTITELESKAHKFIEYMKENWRE"
     gene            complement(27127..29775)
                     /gene="polA"
                     /locus_tag="ACGI5H_001284"
     CDS             complement(27127..29775)
                     /gene="polA"
                     /locus_tag="ACGI5H_001284"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438039.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003676 - nucleic acid binding [Evidence
                     IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003887 - DNA-directed DNA polymerase
                     activity [Evidence IEA];
                     GO_function: GO:0008408 - 3'-5' exonuclease activity
                     [Evidence IEA];
                     GO_process: GO:0006261 - DNA-templated DNA replication
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase I"
                     /protein_id="HFG9696996.1"
                     /translation="MEKKLIIIDGNSIINRAFYALPEMNNKEGLKTNAIYGFTTMLFK
                     MIDIYKPTHISVAFDRKAPTFRHLEYKEYKAGRKGMPDELAEQLQPLKDLLDKFRINR
                     LEIDGYEADDIIGTVSKKAEENGYKVYIVTGDKDAIQLASDNTTTLITKKGVGEVEEY
                     NFNSVIEKYEMTPTQFIDLKGLMGDKSDNIPGVPGIGEKTGIKLIKEFSSIENLIENT
                     DKLKGSVKKKIEENKEIAIQSKRLATIIRDVPIEVDLDSMIFGDYDKDELLDKFRYFG
                     FTSLLSRLVDLVDSDDTEHVEEKIEILKLKDIEKFIDEVNKKGQVILKTVRGQGNILE
                     KNIIYIFISVDGEKIYYVDSNEVSKLDSIFSNNEIKKYGYNLKDDYISLKPYNINLEN
                     MYFDITIAEYLIDSTSSTSYDCSAIAMKYLSKKVKSKEELLGKGVKSKNYEDLEFEDL
                     AEYMGQIICTVKETVPMMERSLMDMSMDGLFYHVEMPLVEVLGHMEYEGIKVDKSILD
                     ELSVEFKEIIATLEKEIYELSGEPFNINSPKQLGVILFEKLELPIIKKTKTGYSTNAD
                     VLEKLRDKHPIIDKITEYRQIVKLNSTYVEGLLNIINPESNRIHSSFNQTITTTGRIS
                     STEPNLQNIPIKMEMGRKIRKVFIADDNCKLVDADYSQVELRVLAHMSQDENMIEAFK
                     HHEDIHTKTASQVFNVPMEDVTSELRGAAKAVNFGIIYGKSDFGLADDLNIPVPKAKE
                     YIESYFAKYHKIKEFMDTTVEKASEDGYAVTILNRRRYIPEIKSSNFMERNRGKRFAM
                     NAPIQGSAADIIKIAMINVHKKLEENNLKSKLILQVHDELIVEAIDDEIDIVKKIVKE
                     EMENAVNMDVHLDVDLNVGSSWYETK"
     gene            29927..30014
                     /locus_tag="ACGI5H_001285"
     tRNA            29927..30014
                     /locus_tag="ACGI5H_001285"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:29961..29963,aa:Leu,seq:caa)
     gene            complement(30201..30644)
                     /locus_tag="ACGI5H_001286"
     CDS             complement(30201..30644)
                     /locus_tag="ACGI5H_001286"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861121.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9696997.1"
                     /translation="MKKNMLYVGIIYFICGILLVLLATFTEFSFEAFIWGLSGAALGP
                     GVCMILQYMYWSKPERAVDYEEKIKNQRIEMNDERRIMLRDKAGRITNQIMSYVLVIL
                     IFIVSILSVFSVMVISKWVLVVLGLLILFQFICSVVVYNKLDKKL"
     gene            complement(30647..30844)
                     /locus_tag="ACGI5H_001287"
     CDS             complement(30647..30844)
                     /locus_tag="ACGI5H_001287"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004631111.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HFG9696998.1"
                     /translation="MKNRLEEIRKERGIKQEELASILQVSRQTIGSLENGRYNPSIIL
                     AFKIARYFDMSIEEIFIYEEE"
     gene            complement(31036..31902)
                     /locus_tag="ACGI5H_001288"
     CDS             complement(31036..31902)
                     /locus_tag="ACGI5H_001288"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729511.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GyrI-like domain-containing protein"
                     /protein_id="HFG9696999.1"
                     /translation="MEWINKLNQAITYIEENLESGVDYAEAAKIACCSTFHFQRMFSY
                     IAEVPLSEYIRRRRMTKAAFELQNSNIKILELSEKYGYDSPTSFNRAFQNIHNISPSA
                     ARAKGVVLKAYPKMTLSIYVKGNIEMQYRIVEKKGFRIVGIKESMNMIVEECFEKVPK
                     LWAKCIKNGTIDKLSELINNEPCGLLGVSVCTNSKGLDYYIAAPTDKPVLEDTHEYLI
                     PSGTWAVFECVSPMPNALAIQELQKRIITEWLPSSGYVYANLPDIELYPNGDINAPDY
                     TTEVWIPIQKPS"
     gene            complement(32128..32997)
                     /locus_tag="ACGI5H_001289"
     CDS             complement(32128..32997)
                     /locus_tag="ACGI5H_001289"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438030.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nitroreductase family protein"
                     /protein_id="HFG9697000.1"
                     /translation="MDYKTIILNRKSVREYKNTDIKEEYLSEIKKYSESCKKLVPEID
                     VDVRIMNRSEVFNNLDKVAGYKGNMIDSPSYIIILSDIKDNYIENSGYIGESIIFKVT
                     ELGIGSCWVTFEDGKKVKEKLGINSDKEVTGIIAIGYGENVSNAKVLNATKTGQNYSK
                     SDMQVVTDKGSTRLGVEDVVYMNEWGNVASIEILEERALLDAFHYARLAPSTLNRQPW
                     RFIVDGGTVVLAVRKDGHTNLYEEKIDIGIVMLYFATIISATMFDLKWNLGTPDKDYK
                     VPEDYKIVGYCNI"
     gene            complement(33503..33724)
                     /locus_tag="ACGI5H_001290"
     CDS             complement(33503..33724)
                     /locus_tag="ACGI5H_001290"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418999.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9697001.1"
                     /translation="MNVNNHKCPECGEHSKKFEIVEENEDCVIFECYTCGTISILKYC
                     ENCKEFVFVNIPNNVETYEYCCGKCNNKI"
     gene            complement(34225..35205)
                     /locus_tag="ACGI5H_001291"
     CDS             complement(34225..35205)
                     /locus_tag="ACGI5H_001291"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418996.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9697002.1"
                     /translation="MGDTSRFYESVKNKYPKLKDGTRVHLWPKENIIIGPIYDEEDGY
                     KKSIGNVDSLSWKQIVILAECDGKNTTDDIINILSNRYRNIHNMKEKVMEFFMFYENV
                     YLTFEDDIQTLSSVFEITGNKSYITPLYFTIEIDGDNNTNDYFSEITSLLNCMYEKGC
                     RFIEVIGEDILKNKSMREIFQYMLDHFDLIVVTKDSFTIDRSLIKELDNYRHKVIWKV
                     YSKNDDTRIKLKEDIKITSLIKRGHTVVRGDREKAIKIEDMRFKDTKERFSKYGAEWS
                     HLYISSDGSVKSYSFQKDKRIYLGNIFNNSVEEIFLEMQNKIDKLEIVYQ"
     gene            complement(35369..36241)
                     /locus_tag="ACGI5H_001292"
     CDS             complement(35369..36241)
                     /locus_tag="ACGI5H_001292"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438026.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metallophosphoesterase"
                     /protein_id="HFG9697003.1"
                     /translation="MIIKVSMTVLVLILLYILYKYETQHIETTEYTIFNKKIPKEFDN
                     FKIVQVSDLHNKVFDKNNKVLIDKIESLNPDVIFITGDLVDGENKNFQVALDLIDNLV
                     EKYEVYHIIGNHEQKSLIKKYKHLYKDYFKELYSKKIINMENESVRIYRGNSHLNLYG
                     LIIPLECYPYLFANSKKLELSDNFVEDNLGKVNENEYNILLAHTPFFFEKYAKWGADL
                     VLAGHVHGGIIRIPFVGGVLSPNREFFPKYDWGKYEKDNSTMILNKGLGGSKVLIRLN
                     CKPEIVKITLKYEK"
     gene            complement(36405..36956)
                     /locus_tag="ACGI5H_001293"
     CDS             complement(36405..36956)
                     /locus_tag="ACGI5H_001293"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888896.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HFG9697004.1"
                     /translation="MDNKFPNVGENLRLLRQEMGISLDKASKMTGVSKAMLGQIERGE
                     SSPTVSTLWKISSGFKINFTTLLNENTNTYEVIKKEEVEPIVEQKGNMKLYPIYPFSP
                     QRRFELFIIELEENCTHVSSTHSHVLEEYVLVIEGKLDLNVDGKTYILESGHSIRFDG
                     TLEHIYKNLNKGKTIFHNIEVYR"
     gene            complement(36976..37878)
                     /locus_tag="ACGI5H_001294"
     CDS             complement(36976..37878)
                     /locus_tag="ACGI5H_001294"
                     /EC_number="1.97.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888895.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0051539 - 4 iron, 4 sulfur cluster binding
                     [Evidence IEA];
                     GO_function: GO:1904047 - S-adenosyl-L-methionine binding
                     [Evidence IEA];
                     GO_process: GO:0043687 - post-translational protein
                     modification [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycyl-radical enzyme activating protein"
                     /protein_id="HFG9697005.1"
                     /translation="MSKKGRVVKVQHFSVNDGDGIRTTIFLEGCKLKCKWCSNPDSWS
                     NIVKLGVMKDKCVSCNRCIDVCPQNISSLFDRAQINNKCDLCGECIKVCLKDAICIMT
                     EEMSVEEIVEEVEKDFIFFFESNGGITFSGGEPTLQIDFLRELVDIFYDKGINIAIET
                     CGYFDWNKVNDVFEKIDHIFVDIKSMDDNIHKEYTGVSNKIILDNICRLSKLNKSMVI
                     RVPIIYGVNDSEENIRNTALFVKQNVPGGKMELLPYHKFGIDKYKALGLEDYIYEFDE
                     ICNNHMLKLKEIVELTGVKIIEYK"
     gene            complement(37893..40265)
                     /locus_tag="ACGI5H_001295"
     CDS             complement(37893..40265)
                     /locus_tag="ACGI5H_001295"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003824 - catalytic activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="formate C-acetyltransferase/glycerol dehydratase
                     family glycyl radical enzyme"
                     /protein_id="HFG9697006.1"
                     /translation="MSQTNRIEAFRQEYINSKPMICCERARIFTESHKKTEGEAICIR
                     RAKAFLETCKELPIKIFENELIVGTAGKFRRTGILTPEFSWQWVDKEMDTFDKRTQDP
                     YVISKEQIEFIRKEIFPYWKGKSLEEVFLARIPEDTAKILVDTGIIDNDSKWRQAVGE
                     VTPDYQDILFVKGYKGIKEDADKKIKELDISVSENIEKIDFYKSVSIVAQGIMTLAQR
                     YSNLAKEMSKQETDEKRKLELIKISEICMNVPANPPTNFYEAIQFVWFVQLGGILSEN
                     PLALNLGRFDQYMYPYYENDAREGKITESEAQELIEALWIKLSEWVWTISANTANYFA
                     GYNQFQNLTVGGKKRNGTDGTNDISYMCLKATESVKTHQPGLSVRVSQGAPDNFVMAV
                     AKLVKQGTGFPAIHSDSAGAQMLLQDGYDAEDARDWSNCGCVVPHFRKTGQWTSAVNI
                     NFAAALEYAMNEGKSRLTGEKMGLDTKNITEFTSFEELKDEFLKQLAYLVKSSVIGTT
                     VAQQIHKEMVPRPFLSTCVDGCLDKGVDLSKGGAKYNIGPVLTGIGLGVVSNSLAAIK
                     KLVFEDKVTTLEELTKALNNDWEGYEELRKLALDVPKYGNDNDYVDSLAIEVSDFYYT
                     ETRKYKDIFGSKFNSAFMGISNYVPTGKIVGATPCGRKATKPLTEGVSPFVGTDTTSP
                     LAAMKSASKINHDVHTGGTLLNLRLNQDLVETERGLRNLTSMIKSYFALGGFHVQFNT
                     ISNDTLLKAQENPEEYKDLLVRVAGYSTQFVNLSREMQDAIIARNSHSNF"
     gene            complement(40486..41175)
                     /locus_tag="ACGI5H_001296"
     CDS             complement(40486..41175)
                     /locus_tag="ACGI5H_001296"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861120.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipoprotein"
                     /protein_id="HFG9697007.1"
                     /translation="MKVKRNINRVAIIVALNLSLALMVGCMSPVSDKNLSSSEQISKD
                     SLKEQVEDKKDESIELFNNYSQKINDAKGREEVKKDLSQRFSKAIIDSGYSITNSKSD
                     GSFVVSINGAEKPPEKNIRSLFYSMSEDDKEGKVTIDILCAKEYPEDDKLSESDKYVK
                     FIYNLFKSLTDTNLTEKEIFSMVEEDFNKGVGVVELPYMKDIHVEVNKVKQSTKVLKL
                     SLVYKFDISNH"
     gene            complement(41416..42795)
                     /locus_tag="ACGI5H_001297"
     CDS             complement(41416..42795)
                     /locus_tag="ACGI5H_001297"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428529.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GHKL domain-containing protein"
                     /protein_id="HFG9697008.1"
                     /translation="MLNFMTELLVVLSIFIQFSIMNGILIYKKDSKKNEKIVFYIVLF
                     LIYIIIQISRLFNGGNYFSNINYLFYILAFIAWGGYYNYFYKMGYIKYSIFFYLFSVY
                     YKCLDAVIYRILFFAITGNVISSKESLLVPYLESIKIQIYSNLIIILIYLIFSFFRKS
                     IKLISQDKRNYVYLLFALLVNTMNMLVNYVLKKLERFGSLHSEGYYFDNFVNPKLVGA
                     SSIFLILLFKEIIKENRLKSQAELIKNKLDMQYAHYLSIQESHMRVKKLYHDINNHIY
                     CIDNLRNNSKEINEYVNNLKDEIKTFKYIYNTGNMILDIIINEKSEVCLKKGIKFTCS
                     INFSKVNFVKPIDVSSIFSNILDNAIEACDKIVDENINKYIRIKGTITRSFFVLKCEN
                     SKLNQLTFNKNILLTNKMDKFVHGIGIQSIKSSLQKYNGELLFENSIDKFILNIYIPL
                     DQDTDSWGD"
     gene            complement(42789..43502)
                     /gene="rgbR"
                     /locus_tag="ACGI5H_001298"
     CDS             complement(42789..43502)
                     /gene="rgbR"
                     /locus_tag="ACGI5H_001298"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438019.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system response regulator RgbR"
                     /protein_id="HFG9697009.1"
                     /translation="MIKIAVCEDEKETQLLIEDYLENILKDISIEYEIQKYISGEELL
                     ESNLKDIDILLLDIKMEKLNGMDTARKIREVDNEMEIIFVTSLIDYVQEGYEVRAYRY
                     LLKPIELEELKKHVLTCIKDIEINKESHITIKNKSNTYKIYLNEIKYIEVQKKDMLIH
                     TINKNFDIKYSLGKIEKELNPYKFIRCHKSFIVNLRYVENIKPNTAILESGEEVPISR
                     YRYKEVKEKFLKFLGDTIC"
     gene            complement(43752..44303)
                     /locus_tag="ACGI5H_001299"
     CDS             complement(43752..44303)
                     /locus_tag="ACGI5H_001299"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896054.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2812 domain-containing protein"
                     /protein_id="HFG9697010.1"
                     /translation="MEKKIKFKFDWYSSPDKIEKWLEDIEAKGYNLYKINKFGGIFYF
                     HKGSPRKIKYTVDYYYDVENNYFDEHKSNGWNLVFRSIGSFMGTSAWYIWSKEYKDIP
                     PKLYSDSDKTNKVKSILFMNMFIFFMLVVIFIYLLNIEIRNLYSGYGASVTAIVLQII
                     LLILYAVQLYRRLMYYLRLKKFK"
     gene            complement(44407..45210)
                     /gene="zupT"
                     /locus_tag="ACGI5H_001300"
     CDS             complement(44407..45210)
                     /gene="zupT"
                     /locus_tag="ACGI5H_001300"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861091.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc transporter ZupT"
                     /protein_id="HFG9697011.1"
                     /translation="MNNVIFAFLITLLAGLSTGIGSCIAFFAKKTNTKFLSISLGFSA
                     GVMIYVSMIEIFPKAQDALTKSMGEKLGSWSTVIAFFIGMAIIAVIDKLIPQEENPHE
                     IKKMENIEEKNIKKNKSLLRTGIFTAMAIAIHNFPEGLATFISALDDVTIAIPIAIAI
                     AIHNIPEGISVSVPVYYATGDKKKAFYYSFLSGMSEPLGAIIGYVLLRNFLNDITLGI
                     VFAIVGGIMVFISLDELLPSAREYGEHHLSIYGLIAGMGVMAISLLLFK"
     gene            complement(45361..46524)
                     /locus_tag="ACGI5H_001301"
     CDS             complement(45361..46524)
                     /locus_tag="ACGI5H_001301"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902264.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M20 family metallopeptidase"
                     /protein_id="HFG9697012.1"
                     /translation="MDIKEITKSYKDYVIKLRREFHENPEKSMEEVRTSKRVKEELDK
                     IGIPYVSAGGTGVIATIKGDNPGKTVALRGDMDALQVVECTDVEYKSKNEGLMHACGH
                     DGHTSMLLGAAKVLNDIKDSINGTVKLFFQPGEEVGKGARAMIQDGAMEGVDSVFGIH
                     LWTDVESGTISVEEGPRMASADFFKITVKGRGGHGSLPHQGVDAVLASSAIVMNLQSM
                     VSREVSPLEPLVVSVGVLNSGTRFNVIASEAILEGTIRLFNPELRKQIPGILERIAKS
                     TAEAYRADAELEYGYLTPAVINDKECSKIATDAAIKLFGEDCITLFEKVTGAEDLAEF
                     MNIAPGALAFVGARNESKGACYPHHHGCFNIDEDALEIGTALYVQYAVDFLNK"
     gene            complement(46584..47771)
                     /locus_tag="ACGI5H_001302"
     CDS             complement(46584..47771)
                     /locus_tag="ACGI5H_001302"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888888.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9697013.1"
                     /translation="MEAITAFCLVLVSLTIGDIVSAKTKAFVPSVFVSAIIFIVGFWT
                     FFPENIVDLAALGTPLAQLGMLLLITHMGTMMSIKELAGQWKTIVIALAGIVGICVGA
                     LALGTVVFGWDTAVIATPPLTGGLVASIMMADAATAKGLASLSVLAILMYVAQGFAGY
                     PITALMLKKEGKRLLSDFRSGKVTVNTDEEKVKDLPEQKSRFKIIPDLPEKYDTTYMI
                     ILRLGFVAWLAVQFTNLTNEVVSRYVICLIFGVIASELGIVDRKPLNKSGSFGWLMTS
                     LMAFIFAGLAKATPAMLVEMAVPLVGIIIFGVIGMGIFSIIVGKLLGESKEMAFSVSL
                     TSLYGFPPNYILTEEAVKALAETPEEKEFLMDKMLPKMLVGGFTTVTIASVVIAGIFV
                     NLI"
     gene            complement(48134..49834)
                     /locus_tag="ACGI5H_001303"
     CDS             complement(48134..49834)
                     /locus_tag="ACGI5H_001303"
                     /EC_number="7.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418965.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HFG9697014.1"
                     /translation="MIKQFVKYYKPYKKIFTLDLIAAFLFSLCDLVYPMITRNIMDDV
                     VPNKNLRMLVVFAVALILIFIAKAGLNYFMQYWGHVIGVDMQADMRNEVFTHLQRLPN
                     TYFDNNKSGVTMSRIVNDLMDITELAHHGPEDLFISIVMLVGSFFILIDINIPLTLII
                     FAILPFIIWFAIAKKDKMNIAFMKSRVTIGDVNATLENSIAGMKVTKSFCTEKEELNK
                     FVRSNKLFRRARQDSYKVMAEYYSGMNLYMDILEWVVVIAGGYFTYIGKITLGDFAAY
                     ILYVKMFIQPMKKLINFTEQYQNGMTGFKRFIEIMEQDHQKEAKNPIELENVKGDIEI
                     ENISFTYEDKTQVLDNLSLSIKAGKTIALVGPSGGGKTTLCNLLPRFYEFDKGDIKID
                     GKSIKDVSLKSLRKNIGIVQQDVFLFTGTIRDNILCGNPNATDEEMIAAAKKARIHDF
                     VETLPDGYDTYIGERGVKLSGGQKQRISISRIFLKNPPIIILDEATSALDNVTEREIQ
                     ESLEELSKDRTNLVVAHRLTTIKNADEIIVLTDKGIEERGTHEELVNKNGVYSRLHNN
                     "
     gene            complement(50077..50352)
                     /locus_tag="ACGI5H_001304"
     CDS             complement(50077..50352)
                     /locus_tag="ACGI5H_001304"
                     /EC_number="2.7.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423118.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HFG9697015.1"
                     /translation="MKKILVACGAGIATSTIVCDRVERLVKENNIQAEVEQCKIAECS
                     TKQEGADLIVSTTILPTTYDIPTIKATGYITGINTTALDKKILNALK"
     gene            complement(50471..51043)
                     /gene="mobB"
                     /locus_tag="ACGI5H_001305"
     CDS             complement(50471..51043)
                     /gene="mobB"
                     /locus_tag="ACGI5H_001305"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438013.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003824 - catalytic activity [Evidence
                     IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_process: GO:0006777 - Mo-molybdopterin cofactor
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="molybdopterin-guanine dinucleotide biosynthesis
                     protein B"
                     /protein_id="HFG9697016.1"
                     /translation="MLLLDSFMKGHNFMYNILSVVSYSGVGKTTLIEGIIKELNKKGY
                     RVGVIKHTCHDFDMDEEGKDTYKHRKSGARKVCIISDKRVAYIEELKEKNPLYKMIQL
                     YEDMDLIIIEGYKNYRFKRLEVTRKGKYEDILSNKSDLIGIVSDIEYKLNIEQFNLND
                     YKNISKYIESCIKNEILSISNVEIKNILKE"
     gene            complement(51027..52208)
                     /locus_tag="ACGI5H_001306"
     CDS             complement(51027..52208)
                     /locus_tag="ACGI5H_001306"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428539.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0030151 - molybdenum ion binding [Evidence
                     IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="molybdopterin molybdotransferase MoeA"
                     /protein_id="HFG9697017.1"
                     /translation="MIELEDAIKIIEKNVLPINRVKIVNLIDAVNKVVAEDIYSTIDS
                     PPFDRSPYDGYAYNANSENRNLKVIGTLYAGDVFNRVLNKNEAVKIMTGGKIPQGANC
                     VIKKEDVTVISDMITLNIKLKEYDNYIFKGEDIKKGQLIINKNQNIGYDGIGVLASLG
                     ISKVTVYDDLKVGILNTGTELQDINETLENGKIYDSNRYTLYSRLLKLGIQADTICNC
                     SDDILELEKKVKNMLQSVDFLITTGGVSVGDKDLIPDVFKKIGATELFWKINIKPGGA
                     CYVGTLGEKLLFGLSGNPHAAIVVFDNVIVPVIEYLTYKKGTHHIKAIFKGEFNKLSN
                     KDRFVSGKLYTSEGKLYVELNDKKDAKARLSATLRSNCMIKIKKNETIKENQLVDVVI
                     R"
     gene            complement(52419..53153)
                     /locus_tag="ACGI5H_001307"
     CDS             complement(52419..53153)
                     /locus_tag="ACGI5H_001307"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418957.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9697018.1"
                     /translation="MKLKRSLVCVTILGIILVGCHKENTKEKNQVASKATQQKTMTKV
                     QNDVNEIMNKDYKYIIKNMGIPYNTFYYIKPKVLKESNTMQDINTSSYMTLVYPKYTG
                     NDELDGSALYVDINENKVVNVETNSFSSQGISVIDAESSIVIEKSDHEKSAVSLENFR
                     HIDLGEYVGVEDSRINEIVGDANYDLTAYNHEGSKVVKSYRLKEDNKILKKEVLTISI
                     VDNKIKSIKTIESDKIVKIIKGTLLE"
BASE COUNT        16813 a         9787 c         5571 g        21044 t
ORIGIN      
        1 ataactaaaa tattgaattt aaaatacata ttattcacaa aatagaatag ctaaaaatat
       61 ttaagaatat tttctattaa atttttattg aaatacaatt tttttacaaa gtatgatata
      121 ttataaacat aaaactattg ttttacatga cttatcatga catcttttgt ttcattcacc
      181 tcaaaatggg gtatgttact tatataatga taaattttag gagggttaaa aatgagtaaa
      241 gtttttgaag taaaaaaaga tatctacttt actggagtag tagatgaagg tttaaaagta
      301 ttcgacataa taatggaaac tgagtttggg acaacttaca actcttattt aatcaaggac
      361 gaaaaaacgg ttttatttga cactgtaaag gcaaatttta aagatgagtt tttaagtaat
      421 ttatcagagg ttactgatat agctaaaatt gactatgttg taattcatca cacagaacca
      481 gaccatgcag gtagtttaaa atacttatta gatataaatc ctaatataga agtttattgt
      541 actaaagctg ctaaactata cttagatggt caaataaata gaccttttaa ctgtcatgta
      601 ataaaagatg gtgaaatttt aaatatcggt aaaagaaatc ttagatttat aactgctcca
      661 ttcttacatt gggttgatac aatgtttact tacattgagg aggacaagac tcttttaact
      721 tgtgatgcat ttggttgtca ctttgcaagt gttgatgcag aggtagtgaa tagtgaagat
      781 tatctaaaat cagctaaaca ctactatgat tgtatagtta agccatttgc taaacatgtt
      841 ttaagtgctg tagataaggt ggtaggacta aacatagaat ttgatactat attgacttct
      901 catggtccaa tgcttactaa agacccaatg gctgctgtta aaagatatgt tgagtggtct
      961 acagaagctg ttaatacaac taatcaaaat caagtttcta tattctactt atcagcttat
     1021 agtaatactt tagagatggc taaaaagata aaagaaggac ttgataaaga aggtgcaaag
     1081 gctgaattat atgatttaga agatatgaca ttaacagaaa tgcacgatac attagtagtg
     1141 tcaaaagtaa tattactagg ctctccaact ataaacaaaa ctatggttaa acctatgtgg
     1201 gatttattct ctgttataga cccaatggct aaccaaggca agatagcagg agtatttggt
     1261 tcatttggtt ggagtggtga aggtataact atggctgaga ctttacttaa atctatgtca
     1321 ttcaaaatgc ctgtagaatc tcttaagaaa aaattcttcc ctagtgaaga gacattaaaa
     1381 gagtgtatgg catttggtgc agaatttgca aaattagtta aatagccatt aatcaaacat
     1441 aatattattt aaaataaatg attttatatt taaaaataaa ttaaaatgga gttgtctcaa
     1501 aattaatttt tctaatctaa ttttaagttc aactcctttt ttattttcca aaatgactaa
     1561 tataataata aatgtaccct ttcgcacagg gtgcattatt tatagtctgt tctatttgta
     1621 tactagtata cttgtattaa ttcacgtatc tagtatatgc tactagccct attccagaat
     1681 tagatgttgt ttcaccaatt tctactttaa taattatatt atttttttac acttttttga
     1741 taattctgct gcagaaaggt tcttaccagt aaaatctaaa gaaaatgcct tatcatactc
     1801 aaaaggataa ctaacaggtt tgctctctgg tgctaatgca accataccat atggtgtatt
     1861 cataaaccct attacagtaa ctgtatgctt tgatgggtct aaatttgaat ttttgcttgt
     1921 aaacttaatt gtatttattg atgagttgat taaactacac ggaactccct catacatttc
     1981 aatttttgga cgtagattat ttccataaac ttcatcaagt attgcccctt gttgatctgc
     2041 tatcatagtg tgattcccag gtccaactgg cgcagaaggc ttagctggcg taggtttctt
     2101 aacagttggc gttggattct gtgtctttac tacttcgcca acagctggat atgctttctt
     2161 gtcaaatggt aatgggtgag taagactctt gtatatgatg tctgctcctg ctgatttgtt
     2221 ggcatcaata tctacatgat acaaacgtcc atcctcaaaa cgaataagat tccactgatg
     2281 gtcatttgtt gtactatgta cataataaca ttcaattccc atagcatcac ataaagcttt
     2341 caagctccta cacattccag aacaagcacc ttttttagta accaatgtat aagcagtatt
     2401 ggctccctct gctgcgttcc agttaacata tgttgtgttg tttttaatgt gattatgtat
     2461 agatacaatc cactatggag aaatataaaa gaaaagaata taacaaacaa taaaaaataa
     2521 gatgattcaa attttatttt gaaacatctt atttactcta caaattaaaa ttatttggtg
     2581 aattatttaa ttattatttt ttattaaaga aattttaaat cttaatataa aatacgctat
     2641 tatacataat aatccaaata cgaatgctac tggaattaac atctccgatt caaaataaaa
     2701 gaaatattct aagaaaatat ctggatttac tatattccca ttcttgtcta aaaaatcttt
     2761 tccattatat cctaaatgct gtataaaatt acttatgtta ttataatctg cttccctctc
     2821 atataccata ttagcattca atccagaaga acttaaatta gtgtttccat ctttcatatc
     2881 tattacatat agtctaagag ctttgacttt actatactta tctttatcaa gtattttttc
     2941 aagttctaac ttatattcac caatctttgt catatcatgt ctttctgcca attgctttat
     3001 ttctccatca agttcttttc ctaaattata catattatgt tgtaaactat tattgtaata
     3061 ccacataaat ccagaaatta aaaatgcaat tatacttatg taacctaata cttttttaaa
     3121 ccccattaca attgatttat gcctatccaa tgataaagat agttctttta ttatattaca
     3181 taattcatac tgcatttcat caccatcatc aaatctttca attgcttttt tacatgcttc
     3241 ttcttcatct aatccttcta atttaaattc atttgcagat tctataagat ggcatctcat
     3301 ttcctgtttt aattctatag tacttttatt gtcacatttt ttatatagtt tatctaaata
     3361 ttcatctatt agtttcataa attaatccac ctctcccaaa aattgattca taaccttttt
     3421 aataaatctc cattcttgtt tctttatttc taaaaaatct ttaccttcat tagttaaatt
     3481 ataatatttt cttcttccac ctgaactttg ttcattgcta taataagatt taattaaatt
     3541 tttagattcc attcttttaa gtgcaagata cattgttcct tcttttaatt caaactcact
     3601 tctttctctt acttgctttg caatttcata tccataacaa tctttctttt ctaatataga
     3661 aacaattaat atatcgatat aaccttttaa cacttcttta tttaactgca ttatgtacca
     3721 ccgccttttc acctactact ctataatgta tagtacttat atttactata atattacata
     3781 gtactctata atacaaggtt tatattctac aatagactta aaaataataa atagctgtat
     3841 attaatattt aatctataaa tactaatata cagctattta tcaaatttta aaaataaatt
     3901 tttgttttat taatgttgtc ataacaacat ttacttggtt gaaatagtat tacctataag
     3961 tttaaatata tataataata gacttgattc tatttcatat tattaaaata gagtaatagt
     4021 ttaaattcta ctactctatc tataatctat ttcctaatta tttaatctca aatttagctc
     4081 ttcatcattt aaatctttca taagatttct acaggtacta gatttattcc aacagaaaaa
     4141 ctagggcatt aaacacttat atatctgttt ctttagactg taatattaat attttttaaa
     4201 tacgttgact tttgcttttt ctaacttctc tccatgatag ttctcctcta tcaagagctt
     4261 ttataaatat ttctgctgaa gctagatttg tagctattgg aacatgataa acatcacaaa
     4321 gtcttattaa cgcttgtata tctgtttcat gagcctgaga tgtcaatggg tctcttaaaa
     4381 aaataactaa atctatttct tgtgttacta ttaaagaacc tatttgctgg tctccaccta
     4441 aaggaccaga tgctaatcta tttatattta attcagtttc atccattatt ctttttcctg
     4501 tagttccagt tgcatatagt ccatactttt ttaaaattga ttcataacct atacaaaatc
     4561 cgaccatagt gtttttcatt tggtcatgtg ctactaatgc tatattcata tatctaatct
     4621 cctcaattta tgtttagatg tatttaaatt tagaaattta ttttctttct tctcatacac
     4681 acatttagta ctaatcctaa gtttgctaaa gatgtcaata acgaacttcc tccataactt
     4741 acaaaaggta atgttactcc agttactggt attaacgcaa ccgtcatacc tatattttgg
     4801 attatctggt aaccaaacat tcccataaca ccaaccacta tgagggttcc ataaaaatct
     4861 tttgcatctc ttgcaattgc taaaagcctt aataggaata tcataaataa gattatcaac
     4921 actgccattc ctattacacc aagttcttca cctacaacag caaatataaa atcactatct
     4981 tgtacaggta aaaaatcttc ttgattttga cttccattgt aaagtccttt accagttacg
     5041 cctccagaac caattgcaat cagagattgc ataacttgat agtttccttt tagagttaca
     5101 tcttctggat ttagaaaagc ttctattctt accttttgat ggtctgccat cattaaatac
     5161 atcagtggca ttgacactaa tagtatgatt attcctcttt ttatcaactt tgaactaaga
     5221 cctgctgtga acagcattgc aaatatcata caacaaaata caattcctgt tcccaagtct
     5281 ggttgtgcaa tcaataatcc gataaatgga agagaataaa ctacaacagg cataacttcc
     5341 tttaacgtat ttaatttatc ctttttggat tcaagtatct ttgcataact tagtacaaat
     5401 gttaatttga ctatttcaga tgtctgcaag tcaagtggtc ctaagttaat ccacgaccta
     5461 gctccacctt ttactgtccc aattccaggt aataaaacta tggctaacaa aataagactt
     5521 attatataaa gcgctttata atacctgcct agaaggttat agtcaaaaaa taatatgact
     5581 ataatcattc ctataccaag tacaaaagct aatccttgtt taatcaattg attatatgaa
     5641 cctgttgaat tagcatgtgt tgcactacta agtataacaa gcccaaaaat aaagatagct
     5701 aatactgtaa ctataagttt ccagtctaac tgttttatca acttaattgt cgacttataa
     5761 ttaatattga tttttttcaa agaatcaccg tctttctatc tttaaacata taattaaata
     5821 aaaggggcat ataccaataa ggatatcccc cttttaagca ctaattacat acatctatct
     5881 tttatattct ttagtggtat attagcaact aatgcagata caggtttgtc atcatgctca
     5941 cctctgcatt tagacatttt tatttcaaga ccatcatctt ctatttctgc ataattagct
     6001 attactttca aaatgtctgt ttttatcatc tctaaaagtt gtggtgaaca atctactcta
     6061 tcatgaacta aaactagctt taacctctct ttagcaacag atttactagt tttagcctcg
     6121 ttagaaaaaa ctctaaataa atctaacaca gatgtatcct cctttgctac ttagccatgc
     6181 taaacatttt tttaagtcta ccaaagaatc catcttcaac ttcaagatca agtagaggaa
     6241 cttcttcatt tagtatcctt tttgcgatat ttttgtatgc ttgaccagca agtgacttag
     6301 aatcaagtat agctggctct cctttatttg ttgatataat tatgctttca tcatcaggaa
     6361 caagacctaa caaatctatt gctaatattt ctattatatc ttgtttatcc atcatgtctc
     6421 cacgcttaac catatcattt ctaattctat ttataactaa tcttatctct tttatttcat
     6481 ttgcttctaa tagacctatt attctatcag catctcttac tgctgatatt tctggattag
     6541 taactacaat agctctatct gccccagcta ctgcattttt aaagccttgc tcaatacctg
     6601 ctggacaatc tattattata tactcgaaag attcttttag tttctcacac aggtcaatca
     6661 tctgctcaac tgagacagca tttttatctc tagtttgtgc tgctggtaat aaatatagat
     6721 tatcaaatct tttgtctttt attagagctt gcttaagcct acaagttcct tcaactacat
     6781 ctactatgtc ataaactatt cgattttcaa gacccattac tacatctaag tttctaagtc
     6841 caatatctgc atccacaact actgtttttt tattttctag gcttagcgca gttcctaagt
     6901 ttgctgcggt agtagttttt ccaaccccac ctttaccaga tgttataact ataacttcgc
     6961 tcataatact accccctatt tttctttcta tttgtctaac tttgacaaat agctttcgat
     7021 tacaattctt ccattactta caaaggctat ttctgggcta atttctgatt cactttcata
     7081 attttcttca tcatctggag cttctgcaat attatctgct atttgtaata ttttaggatt
     7141 aagatttcca gcaacaacat atgcaaattc attgccttct gcacctgcat gtacaaaacc
     7201 ttctatttta cccattacaa aaacattacc tcctgctaca accttagcac cagcatttat
     7261 atctcccata acaactgtat ttgattttga aaggactttt gaaccaggtt tcatatcatt
     7321 caatataact acatcacctt caaattcaat attttcacca gatcttaggg tattgacata
     7381 ttttgttgga aaattactat tttcttcaat tttttgatct tcaacaaatt ccacatcaaa
     7441 tctagaagta attccttctt taagttctag aatctccatg tcagttaaac aatcactatt
     7501 aattttacta attttagccc cattaaaaaa gccaacatat gcttccaatt tgtttattat
     7561 tttttcctgt atttcctcaa atggagcttc tctttttata tttactatta tccctctttt
     7621 attacccttg aactctacta gttcttgact acaaatttct cttaaagaca taacaacctc
     7681 cagagtgata tatcatttat attcttcaaa tacgctttaa acccttttat tttttctata
     7741 taaagctaaa gtttatacat agattgagct atctattaat ttgtgactcg aaatttatat
     7801 tttcgtcaga agaattgtta acatcattcg tcttgttgtc atttttacta ttagttggct
     7861 ctaatcccat ataagttcca ataacttctc tagttggtaa aagtgagaat acacttgaat
     7921 caccttgagg aattacacat acaacagcta tttctgggtc atctgctgga gcaaaagcaa
     7981 cagtccacgt aaaagaacca taatcttgtt taaatctatc tatttggtca tctgttattt
     8041 ttggatttaa ttcttttata gcttttctta gatatgaaga attcacctta tcagtgtcct
     8101 ctaatctaac ttttactcca tcttctaatt cttcctctaa tttctttctt tcttcgtctt
     8161 tcaaatcttt attttctaat ttctttttta tttccttttc cttagctaat gaaagctctt
     8221 tttctttttc tgctttcatc ttatcagcta gtttaatcgc atcatttagg ttgacattat
     8281 aagatgacat atgacttttt aaatattcat actcgttatc tgtaggtatt ttcccacttt
     8341 tctcagctgt accagttttt gctgctacat ctattggaaa atcagcaaaa gcactcttcg
     8401 ctgtaccttg tcttgcaacc aatttcatac cttttgttaa ttcttttaag ttatctggat
     8461 ttttaaaagg tattttttcg actttcttct ggtcattaat tttaactgat gaataatcac
     8521 ttgaaacagc tctatcaact acagataatt ctactaaatt acctccattt gctatagcag
     8581 ctacatatct tgatatttga gctagtgtat aagcattttc accttgacct atagctaagt
     8641 taaatgtatc tgcagtactc cattttgcaa agttaaaata actaaatact gctaaatctg
     8701 ctacttcttc aattctatct tctttaacat ccaatttttt tagcctattc attgtttcaa
     8761 ctctaccagg agttttcttt tctgctgccc agcttacaat ctcattgatt cttttctcat
     8821 attctttagg atttttttct ctagttatat caacaaaatc atttgccatt tctctttcta
     8881 aatttgactt tagaagagct tgtgttgatt tcaatttatc ttctgtgcta ggaactttac
     8941 ctgctctttc ttctacttca tcttgaagcc ctgtattttg gtcaagccca aataattttg
     9001 catactcaag tattttattt gcattcatat ctataccaat gctttttcca tctggccatg
     9061 ttttacctgt accaattgtt gccatatata tattacaaga ctcttgtatt gctttatata
     9121 agtttgtcat accatggttt cctctaccat ggttccatac atagtcacca aaagattttt
     9181 tacctaacat tataacccca gggtcattta tagtaaagtt tggatccaga ccattttcta
     9241 acgctgccat tgaagttacc atcttaaatg aagaacctgg ctgaaattcc ccttgtgtaa
     9301 ccaagtttaa aagtggactt cctgctagta agtcatttgg attttttggt tgaagtgctt
     9361 tataatcctc tgtagaaata ccttttgcaa atttatttgg gtcataatta ggataacttg
     9421 atgaagctaa tacttctcca tttttaacat caatagctat aagagctgct gactgtgctt
     9481 ttcctgcata tgcactaatt ggtttgtccc caaatttact tttaaaagta cctcctttag
     9541 aagcaacttc gattatctgt tttaatgcat tgtctgaaac ttcttgtaaa tctttatcta
     9601 gtgtaagata cacagtatct cctgatttag gttttttaga ttcaatttct ttactgattc
     9661 tacccaatgc atcaacttta accattttat aaccatcagt tcctcttaat ctactttcat
     9721 tactcttttc tactcctgca agacctacca tatctccagt ttcataacct ttttgaaggt
     9781 atgattctat ttgagtggat ggcatttttc ctacatatcc taacatatga gaagctaatg
     9841 acccattagg ataatatctt actggttcta ctgctattga aacaccaaca aggtccatag
     9901 cactttcttc aatttgagca atcgtagttt ctcctacatc cttagcaata gttactggat
     9961 tatattgaga atatcctttt gattttatca aatcccttac gaccattatt tttcttgcat
    10021 cttcatcact caaactttta tcaatttcta atgcatcact atttcttact ttttcaaacg
    10081 cttctttggc actcagttta gtttctttta tcttataact agccaaccaa tctctcttat
    10141 ctctttctgc tgtgaacatc catttactaa ctaaaatagg tggataatat ccattttcat
    10201 ttagttttgc ctgtaatctt gtcgcatcca atcttttatc ttcttgagat aatattccag
    10261 ctgatataag tttgtccacc aagtaataaa aactttcctt agcattataa tcatttggaa
    10321 taccattttc tgatttatat tccctaatat ctctgtcata tgtataatag tactttccat
    10381 tttctacata tataggaaac tcatctacat attcttcacc atttctctcc agcaaattta
    10441 taagttttaa tgatatttca tttgctcttg aatgcttatt tgcatctttc ttattaatat
    10501 cgttacctga aacttgaaca gtaaataagt ttttatttcc tgccaacagt cttccatatc
    10561 tatcttttat ttctcctctt ggagcttcta ttgccaactt tttatatgtt ttattctcag
    10621 ctaactcatt gtaatattca tatttaaatg tagtcatata gattattttt actaaaatag
    10681 ctaaaaatat cacgcccatg actatcttaa ttatttttag tctatcaact tgtttatttt
    10741 cttccatgaa atcaccaact aatcttcttt aagttttaaa actgctcttt tagataagcg
    10801 atatattact aaaccaatta aactattcac tattggtgct actagtagac cttttacaaa
    10861 aagtgttgat atgttgtagc tttgataaat tatactagat gtacctatat tgacaattga
    10921 atcaattaaa ctgcctataa aaattaaaac gaaagtaata atataactac ctttatatag
    10981 ctgatctctc atgtatccaa ttgcatatgc aataataaac aaaattaatg catttacacc
    11041 aaaaattcca ccaacggtta tgtctttaat aagccctatt attgctgcta taatcccacc
    11101 ttctaattca tctaaataaa gagagattat ggttacatat ataagaacta aattaaagct
    11161 tatgccaaaa atatctatat aatttgttat actattttct atagtcataa gcacaatccc
    11221 caacagacaa agtaaaactt ttttcattgt ttttatcccc tttatcctat atttcttggt
    11281 tctatgacta caacgtcatt tatattctta aaatcaacat aaggttttac aactacatat
    11341 tttaatgact tatctttatc atcaaccact ttttcaactt cgccaattgg tataccatct
    11401 gggaagaatc caagacctga tgttgttatt atatctcctt gaattacatt atatgatgag
    11461 tcaaacatat atccttgcaa atatccttta ctattataac tatctttatt atctaaagta
    11521 gtattttgag taattgtacc tttagcattg gcatcctttg ctagtttaaa gcttacagat
    11581 gccttagaat ccaatagtga aattgcctta ctataattgt tggaaacttc ataaactatg
    11641 ccaactaatc cactaccatt cataactata ctttcttttt ttacacctga attttttcct
    11701 gcacctatga caaaactctc ataccagttt ccatcatttt taccaacaac acttgctgaa
    11761 atacttgtcg ccttatactc ttcttgtaca aagttcagtg tcttttttaa ctcttctagc
    11821 gattctgttt tatctagttt ggcatttaaa gctatcatat tttttttaag tttttcattt
    11881 tcttcttcta atttttttac ctttttagaa ttatctttaa aatttgctac atctttaaaa
    11941 ccatttttga taaaagaaaa tccatcattt attcccttac ctacacttgt aatagcatct
    12001 gaagctactc ctaaatttac tggactacca ctagaaaatt taccaattga tatacccaca
    12061 attccaatta aagtgatagc aactacgccc gttgctatca ctttaacatt aatccttttt
    12121 ttctcatttt tgttcttgtc aaatctcaag gccatcacca acttctaatt cttagtattc
    12181 atcattaata ctttttcaaa gatttcttgg tcttcaacag atttacctgt tccaagtgca
    12241 acacaatcaa gaggtgtttc tgctatttgt acagacatac cagtttcctg tgtaataagc
    12301 ttatcaagac ctctaagcaa agcgcctcct cctgttagca ttattccgtt ttccattata
    12361 tctgaggcta attctggtgg agttctttct agtgtagatt ttattgcatc tactattgaa
    12421 cttacaggtt cttttaatgc ttctctaact tctgtagagc atatttctat tgttttaggt
    12481 aatcctgaga ttaaatctct acctcttatt tgcatattta tttcttcatc atctttaaat
    12541 gtagaaccta tgttaatttt tacattttca gcagttcttt cacctatcat aagattatat
    12601 tcttttttta cataagccac tatagactcg tcaaattcgt ctccacctat tcttatagat
    12661 ttagcagtaa cgattcctcc taaagatatt acagctattt ctgaagtacc tccaccaata
    12721 tcaactacca tattaccttc tggttcttca acttttaatc cagcccctat agccgctgcc
    12781 attggctctt ctataaggaa tgcatcttta gctcctgctt gtcttgcagc ctcttctata
    12841 gctctctttt ctacttctgt aactccaaaa ggaacacata tagctattct tggacttaca
    12901 acaccttttt tatcagccgc tttttgtata aaatagctaa tcattgattg agttatgtca
    12961 aaatcagcta ttactccatc tttcataggt cttatagcta ctatatttcc tggtgttcta
    13021 cctatcattt ttttggcttc ttcacctact gctaatacct ctttactatc atctcttatt
    13081 gcgacaactg atggttctct aacaacaata ccttgtcctt ttatgtaaac taatgtattt
    13141 gcagtcccta aatctattcc catatccttt gtcatcttat taaaactaaa aaaacctttt
    13201 ttttctttct ttttttcctt agccatgatt ttactccttc ctactattaa gaatcatgtt
    13261 taaaacattc ttctattatt ttatcacata taaagtcaaa ttatcatatt ttctttaaag
    13321 ctaaagtata atccatctcc aataattata tggtctatta tttctattcc aattatttct
    13381 ccacatttaa taagtcttga tgtgatattt ttatcttctc ttgatggttc tacacttcct
    13441 gaagggtgat tatgcatcac tattatctta cttgcacttc ttcttatagc ttctttaaaa
    13501 acctctcttg gatggactaa tgacgagctt aaagtcccta tagatacatc tacatcagat
    13561 attatctcat tttttgtgtt taaaagaacc gctttaaaaa cctctttttt taaatacctt
    13621 aggctatcca tataatacct ctgtatatcc caaggattcc ttattttata ctttataggt
    13681 ttaaaactag ctactctaga gcctagttct aaagctgctt taatttgggt tgattttgat
    13741 aacccaattc catctatatt acacagctcc tctattgtca tatcttctaa atgtctaata
    13801 ccctgaatat ctctatttat tatatagttg gctaattcaa tagcattttt attcttgttg
    13861 ccagttctta aaagtatagc caacaactca gcatttgata agctttttac gcctttggca
    13921 agcatctttt ctctgggtct ttcctctggt gccatttctt ttaccttaat ggttgaatta
    13981 aatgactttt tcagataaat cacactccat aaaaaagatt tatactaaaa tattttttta
    14041 ataggtcgcc taaccttgaa attggaagac caactatatt aaaataatct cctctaattt
    14101 cttcaactaa caaagctcca taaccttgta taccataggc tcctgctttg tcaaatgact
    14161 cattagtttt cagataatcc tcaatatcct gctctgataa cgttttaaat ttcacattgc
    14221 tgattacata gtcaattacc tttttatctt cgcacaagtt tattaagcta atacctgtta
    14281 tgacttgatg ctctcttcca gatagtcttt ttaacatatc tcttgcacaa gactcatctt
    14341 ttggttttcc taaaatagca ttgtctaaaa caacaactgt atcagctcca ataacaacat
    14401 cttcattatg ttcagatgct acagacatac ttttttcaaa agctaatctc ataactaaat
    14461 gttttggtgt ttcaccttcc aatataatct catcaatttc atttttaatt atatcaaatc
    14521 ttacattcgt attctctaga atttctttcc ttcttggaga ggctgatgcc aagattatat
    14581 tcatttattc acctcatttg tacgtaattt gtacctattt agtctatcac tatattgtaa
    14641 aaaattcaac agaaatgtcg aacctttttt gttacactat tgttatattt attaccatta
    14701 gaataaatat acataaaata gaggtatgga aattattcca tacctctgtt ttatgtactc
    14761 attagagata tggaaattat tccatatcct tattttgtcc atattacaaa attttaatag
    14821 ctttctttgg acatttttcc atacataaat ggcatcctac acatttatct gcatctacct
    14881 tatgtttttc ttttaattct ccctctattg catcaaactt acattgtttt ttgcacactg
    14941 tacatccaac acaaagttct tggtcaatag taactttctt tttcttagtt atgtcacctg
    15001 atattacttt tgtagggcat tttgctacac attgcataca acctacacac ttattagggt
    15061 ctatcttagc tattttgtct tcaaatatta ttgcatcaaa tttacaagct tttacacaca
    15121 ttccacagcc aatacatcca gcagtacatt tttctttaac agctttacca aactctttgc
    15181 tattacactc tacaactact tcttgacttt ctggttttgt gattattata cccttaggac
    15241 aaacttcttt acattttcca caatttacac acttttcttc atctattact gctattccat
    15301 caactataga aatagcatca aatttacaag catctttaca tgttccaaga cctaaacatc
    15361 caaatttaca catcttagca cctgagttta aaacatttgc tgctctacaa tctgatattc
    15421 cttcatactc atatttatct tttgcacttg aacaagttcc tttacaaata acttttgcta
    15481 cttgtttctc acctgcttca gcacttattc ccattatttc tccaactttt gcaccaacat
    15541 ctgctccacc tacagggcaa ccattaactg gtgcattgcc ttcaactatc gcatttgcaa
    15601 gacctccaca acctggaaat ccacaacctc cacagttggc tcctggaagt actcctagta
    15661 tagcttccac tctctcgtct acttctacag caaacttttt agatgcaaaa tctagtacta
    15721 tcccgaagat taagcccata attcctaaaa ctaatacagc tgtaagtatc accattttca
    15781 cccctctttt ttatagcttt ataagtcctg taaatcctaa gaaagctatt gacattaaac
    15841 ctgctgatat aagcgttata gggaaacctt taaatgcttc tggtatatca gctaattcta
    15901 gtctttctct tatacctgcg aatattacta ttgctaaagt aaatccagct ccggctccaa
    15961 atccgtttat tattgtttct actaaattat aacttttttg aacattaact agagctatac
    16021 caagaactgc acagtttgta gttataagag gtaaataaac tcctaatgct tgatataaag
    16081 atggactcat cttttgaatt accatttcaa cgaactgaac tatagaagct ataaccaata
    16141 taaaagctat tgtttgtaag aatccagttc cagtttttac taataaaatc tgtataaaat
    16201 aagttataat tgaagctaga gttaaaacga acgtaactgc aactcccatc cctactgctg
    16261 tatcaacctt cttagaaact cccaagaaag gacatatacc caagaattga gatgttataa
    16321 cgttattaac aagaacgata cttaaaaata aaagtattaa attcatttat tacacctcca
    16381 ctatgctttt ttacttctta atttattaaa tcctgcaaat aagaatccta atgttaagaa
    16441 tgcacctggt ggtaatataa atattaatac tggttggaaa gatgctccaa ataatgtcat
    16501 tccaaataaa ctaccatttc caagtaattc tcttactgca cctattattg taagtgcaac
    16561 agtaaatcca agaccttgac ctacaccatc aactattgaa ggcatagctc ctgttttgaa
    16621 agcaaaactt tctgcacgag ctaatattaa acagttaaca actattaatg gtatatatat
    16681 accaagagcc ttatcaagag caggaacata tgcttttaaa agcataccta ctattgtaac
    16741 aaatgtagct ataactacta taaatatagg tattcttatc ttatctggtg taatttttct
    16801 tattaaagat ataactaaat ttgcacatat taaaactgct gctgttgaaa gacccatacc
    16861 aattccattt attgctgaag ttgtaacggc tagtgttgga cacataccta taacttgaac
    16921 aaatgttggg ttctcatcta ttagcccatt tttaaatact ttagctaaat tcataattaa
    16981 ccctccttat ttattaagag cactattgaa aacatctata gcagcattta ctcctgtagt
    17041 aactgctgta gatgtaatag ttgcacctga tattgctaat atttgattat ctgctgttgt
    17101 acttcctttt gctacttcaa gaggctcagc agtttttcct ttgtattgac ccttaaatgc
    17161 atcatcctta gcttttgctc caagacctgc tgtttctgac atattaccaa tgtcaacacc
    17221 tgtaacttga ccttcagatg atatacctac cataacttca atttctccac catatccact
    17281 tggtttagct tttaaagtat atccaaccac ttcagaacca tctaaacctt catacacttc
    17341 agctataaga ccatctccaa ggcctttgta agtatcttcc ttcatttctt taaattcttt
    17401 tgcttctgga aggactgctt ttctaagttc attatttgct tgtatatttc tttgttctat
    17461 tactggagct gtaacctgat tagtagctcc aagagctaat gcagctattg cacttatagc
    17521 aagtaaagta ccacctaatc tcaccatact gttcattatt tagccacctc cccaaatact
    17581 ctatttctaa caaacttatc tataagtgga gcaagacagt tcactaatag tattgagtaa
    17641 gatacacctt ctggatatcc accatacatt cttataacag ttgttataag accagctaat
    17701 acagcgtata ttatttgacc ttttttagtc ataggcgaag ttgtataatc cgtaagcatg
    17761 aagaatccac ctaacataag tcctccagca aacagttgat atattgcgaa agttatatta
    17821 aatccaccta aaaggaatgt taatataaat acagttgcta tgtaaaatac tggtataaca
    17881 taatttatta tgcctttata cattaggtat actccaccta ataataataa tattgctgat
    17941 gtctcaccta tacatccacc aatattccct atcatcatgt cagcaagact aattccattg
    18001 ctagaaaggt ctgccagtcc tgctgctcca tttttcaaaa agcttaatgg agttgctgta
    18061 gtaactgcat ctaaattttt acctatccag ttaacacctg gttgagtcca agcagtcatt
    18121 gctactggga atgatgctaa taaaaatgct cttgcagcaa gtgctggatt gacaaagtta
    18181 catccaattc caccaaatac cattttaact actaatattg caaatattcc tcctactaga
    18241 cacatccacc aaggaagtga tgctggtacg ttaaatgcta ataataatcc tgttacaaca
    18301 gctgaaaaat ctcctatagt acttttttgc ttcgtaaatt tttgatataa aaattcagta
    18361 cctactgtac caagtataca aaaaaacata gcactcaaag cattaagtct aaagaagtat
    18421 actcctgcta ctgctgctgg aaggagtgct ataataactt gtttcattat atatgaagta
    18481 tcttcattac ttctcacatg aggagaagat gatactatca acttattttc catcgttttt
    18541 cccccttaac tttctttatt tctgagcagc ttgctttctt ctctttgctc ctatttctct
    18601 ctttgctgat cttatagatt gaagtaatgg tcttcttgct ggacaaataa atgagcaaga
    18661 cccacattct atacaatcca ttgctctatg atattcagct gtgtcatagt catcttttaa
    18721 agaatatgca cttatgaaaa gtggttgtaa gaatgatgga catacatctg tacatcttcc
    18781 acatcttaaa cagttttgaa tatctggagt acgtgattct tcctcatcca aacataaaat
    18841 tcctgaagaa cctttgttag tcgctatttc agtagtatat tgagctattc ccatcatagg
    18901 tccacccatt ataaccttac caatcttctt atcttcttta aatccaccac attgttctat
    18961 tatttctgaa actaatgttc caacttttgt tattaggttc tttggctctt tgatgcaact
    19021 acctgttatt gtagtgattc tttcaaccaa aggcatacct gttttaatag acttagctat
    19081 ctgtgctgct gtggcaacgt tgtcaacaac tgcacctgct gctattggta atccaccaga
    19141 tggaacttct ttgcctgtac acgcataaat aagttgtttc tctgctcctt gtggatattt
    19201 cacttgaagg ccaacaactt cgatttcgct atagtcttta gctacatttt gaattgcttc
    19261 tatagcatct ggtttattcg tttcaattcc tataaatcct tttttgacat ctaatacctt
    19321 cattaatgct cttaaaccaa acacaacatc ttctggattt tcaaccatta atctgtggtc
    19381 tgcagttaag tatggttcac attctgcacc atttaatata actacttctg ccttgctatc
    19441 tggtggagga gatactttta catggttagg gaatgtagct ccacccatac ctactattcc
    19501 tgcctctttt atgataccta ctatatcttc tttgctcaaa tcctctaact gaccttttgg
    19561 ttgaacactc tcatgtaatt cttccttaaa gtcattttcg ataactacac attgagctga
    19621 acctcctggt acttcatgtt gttcaatagc aataacttta cctgatactg aagaatgaac
    19681 gttacatgaa acaaaacctt gttgttcacc tattttttgc ccaaacttta cttcatcacc
    19741 aacttcaaca ataggtttag ctggtgcccc tatatgttgc tgaagaggaa tgtaaactat
    19801 ctttggagct tgagcttttt caagtgcctt tgtgttagag tactcttttc tatatggagg
    19861 atgtatccct cccttaaaag ttaagagttt cattgtttta cccccttatc tataaaaaaa
    19921 cattttttct gccttctata agtatactat atatattaaa aaatcttaac aattgttaaa
    19981 aaaatatccg tatttttata atttatttta taaatcaaca cctctatatt aagtcaaatt
    20041 gaggaaaagg attgcttaat taaacaatcc ttttcatata gctttctaaa gtccaaattt
    20101 tctgtatttt attttataga atttataaac atagagtact cctgcatgga tgataaaagc
    20161 agacttttac ttacactata tttttcttca tttgctgctt ttgaagctgt atcaattttt
    20221 tcattcacat tctttacata ctctattaaa ttatctttaa ataaacgcat ttcagaataa
    20281 tcaatctttt cagcttcttt tgatatattt tgtgatattg cctttctatt tgtcaaaata
    20341 gtattatatt tttccatatc tacattattt tcagcattcg accaaaaact tgattcttct
    20401 ttaaagtttg ttattaattt atttaattct ttagatatac tctctatata agcgtagtta
    20461 cttgtatact ctaaagacaa cataggtgca tctaagtgtg ataaaaatgc atctggaaac
    20521 acctttctta cactgcttat ctgctttcta acatcatttt catcaaaaga ggaataggtc
    20581 tgtatttttt ttactccatc cttctccata actgaaaaag gtatgtcatt attaactaat
    20641 gatgtctgta tttttttcaa atcatcatta ttatctattg cagcaacttg aatagtatac
    20701 atatcccagc cttctatagt agctaatttg acttcttctg gctctttagt gttatttacc
    20761 gctttttctg gattagtttc ttgtttatca tctgaattgg tttgtgattt agattttttc
    20821 ccttttttta ttgaatttaa ttcatcagat atatctttat aagttatatc tgatgaatta
    20881 tttagaaatg gtattttagc cgatacatac tccaatatct tgctatcttt tatttttgta
    20941 taagaataat agccaattag acacaagcaa gcaatcgtta taacatattt acgtaaatca
    21001 atcttatgtc tattattatt aaatcctctg tatatcgttt ttcttctatt cattagtttg
    21061 tccctcccaa aattatatta ttaataaagt atatttttaa gagtcacaat ttatgaatat
    21121 aaataattat ttcttctaat tttttaataa gaaattgtac ttactaaaca aatcttcttg
    21181 caccaagtaa tactttagac caatatgaac tagttaaatt atccacttta accttattag
    21241 gattagtctg agtaccacta caatggataa atttactatt tcctacgtat atacctacat
    21301 gattagttgt tccatcacca tcagtgtcaa aataaactaa atctcctggt gcataatttc
    21361 ccatagaaat tgcacttcca aaattagcct gttctctaga aactctagga atagaaacgc
    21421 ctacagaatg tttaaaaaca tactgtgtaa atccagaaca gtcaaattta tcaggtcctg
    21481 aagctcccca ttgatatggt attccaataa gagtatatgc aaaatctacg attgttgaac
    21541 cttttgctgt agatttatct gaatttccag taaatgatgg ctttgagtta ctattagatt
    21601 gagaattttg gttagatgat gaatttggtt tttcttttgt atcctcatta gtctcagaaa
    21661 tataactggc actcacccat ccaattgttc cactcgataa ctttacctta taccaaccat
    21721 tacttttagc ttttaattca acaacatctc caccatttaa ttttcctatt atagaatagc
    21781 ttgtcccagg accacttctt acatttaaac tcacagcaga tgttacctta ccattcttgc
    21841 cttcaattga ttcttcgcta gatggttttt tatcagaatt attagtacta tttgaattac
    21901 tagaattgtt cgttccaaca tcttctgatg ttttagaaat atattggcta ctagcccatc
    21961 cagtaactcc atttgatagt tttattttat accatccatt gctttgttct agtaacttta
    22021 ctacatctcc attatttgct ttaccaacta atgaatagtt agtacctgca ccacttctta
    22081 cattcagtct agaactcaca tttactttac catttccact aatagttgtc ccacttgaag
    22141 ttggattatt ttgacttgat gtaccttcag acgaaccact tgttgatatg tattttgcac
    22201 ttccccatcc aacaacagaa ctcgataccc ttactttata ccatccatta gacttttcta
    22261 aaatctctac agtttttccc ttgtataatt ttgctacctt atcgcaatca gaacttggtc
    22321 cacttcttat attcaaggca cttgctgtta ctgttccctt ttcaagagca cttgcattta
    22381 tggagctaac agatactgct actgccccaa ttcctaaagc tgctatagct tttttcacta
    22441 ctatcactcc ccccaacaaa tttttatagt cataaattca taacattatt atccattttt
    22501 agtccctaca atttaatgat aacttatttt cttattaatt gtaaagaaat tataaacata
    22561 tccttaaaat tagtgatttt taggaagtat ttcaatccaa taattatctg ggtccgctat
    22621 aaaataaatt cccatacttt cattttcaaa acatatgcaa tctaaatctt tatgaagttt
    22681 ttttgcctca tcaaactcct caacttctaa agccagatga aattcattgt ctcctaaatt
    22741 atatggtcta tcccaatctc taagccaagt taattctaat gtatgactag taatgccatc
    22801 tcctaaataa actaatataa aacttccatc ttctgcttcc ttgcgcttta cctctttaag
    22861 ccctaaagct tttttataaa aatctaaact tttttctaaa ttagtaacat tgaaattgtt
    22921 atgacaaaaa ttaaacttca ttttgaaatc actctccaat ttttattttt tttatattat
    22981 atcattatta taaatttatt taaatcatat taagttaaaa atttgaatga tgatgaccaa
    23041 ttaccaaatc atggtaaatt atttaaaaga atatgtcaaa aaaagaataa gctctttcaa
    23101 atgcataaaa aatttatacc caagttatac ttaatcatgc aaattggcag aacttattct
    23161 ttaaaactct aacttttaag tttttcttta ataatataat ttattacttt ttttctaata
    23221 tcttcagcat tataatcatc ttctacttct atatccaaaa gttttgctat tgacctcata
    23281 tcttctctag tctttgacct atagcttgat attaattcat cttttatttt ctctggttct
    23341 aaaagatatt cttcatctcc tcttttgaaa acaacgtatt tttgagcata tgaacttcta
    23401 ttgtagtata tatatcttga tatttttctt aaaatttgat tatatgaaag tcgcttgtta
    23461 atatcaagtt ttaagtactc tgaaaaagca aatagctctt tttttgattt aaataatgct
    23521 tctttcttta tagttcttga tattgaagtt acactttctt gatatgcaca cttttttaac
    23581 atttttaaat atactctatt aagaccaata ctttgattga atttttttat attattatta
    23641 ataatcttat ccaagttacc ttcaaagtat ttttttgctc ctttttgtga tacataactc
    23701 tcaagttctt tgtgggccat atcaagtatc atttttttta aatcctcttt atatccccta
    23761 gattccatga tactccctcc cttagctatt tatagtatat tcaaaaagct caagaaatgt
    23821 gagtcattac aaaatttttt tactttttat gtatatatta atttaaaagg ggagataata
    23881 gtaatgtaaa atcaaacata ctcaatctcc cccattttta gacctctatt actcccccaa
    23941 tagaggtctt tttttagttt atcaatttct attcaattcc ctttagttca aatcctaatt
    24001 ctgctatcac ttcttttaat ttttcaatag atacatcatc tttcatatct acagatgcac
    24061 acttattttc taaatctaca tctaaaactt caataccatc tatatcttct gttaatgcag
    24121 ttttaagatg gtttacacaa tgaccacaac tcataccttc tactaatagt ttcttcttca
    24181 tttaattacc tccttatacc ctataagggt attctatcat atagtttata ctttttaaat
    24241 agaaattaat catttaattt gattcattcg attttatatc taaattagat attccctcat
    24301 atacatcaaa atcatttgga gtaattttac cttttaatct actattactt acaatatagt
    24361 tgtttctcac agctaaactt ataaatgttg cattatcttt tatatatgtc tgtacatctt
    24421 tgtatgcttt ttttgtttca atttcagacg tagaacttgt aagtgcagac atatatccat
    24481 ttaacttatc atcagtatat ccactactcg ctataatact acttgcatct ggtataattg
    24541 atagtttcca tccaactaat gctaaatcat aatttttaga attaagagca ttttccatat
    24601 ccttatctga gagctgattt actgtactat ttattcctat agcttttaag ttttcattta
    24661 ttatgtttgc agtttttatt ctctcactat tatctctgtt tactattatc tttaagttca
    24721 tttcagaaag acttttcttt acttcctctt tttctctatt ttttttctct tcagcttctt
    24781 ttttgattct atcttcttct gcttttttaa cttttgcttc ttcttctggc gtaagcttct
    24841 ttgagttctt tttagctgat tttttctgat tttttacttt attgtcattt tgatttactg
    24901 agtttacatt tgcatattct accttagcaa gacactctat cgccttatct ttattaaact
    24961 ctaaatcctt catttcacta ttatagtatt ttgattttga attaagtgga aaattaactg
    25021 gagtagcatc atccatataa ccttcactaa taattctatc tttatctata gagtgtgcaa
    25081 ttgcttttct aaaattaaca tctttgaaaa aaggattatt ataattaaat aatacacact
    25141 cataatctct tccttgatat tttgttatat taaactcttt ttcttgaaac ttacttaaat
    25201 catttaatgt aacattggtt atatcactat caagagccat aaccatagat gtccttgcat
    25261 cttcattagg caccatacct acttttatgt tcttcatggt ttttggaact tcttcatagt
    25321 aatctttgtt tacagataaa accattcctt ctctttctgt atatgattct attttatatt
    25381 tcccatttcc tatcatatta ttattcttgt catttacatc ttttgaatct aaatgatttt
    25441 gagatacaat tggaaaaatt aaactatcaa ttgaaaaagc atatctagct ttaaatttta
    25501 ttgtaaaatc tttatctgat ttaatattca cagaagctat atttttagta aattcattat
    25561 atggactatc tgcacttttt tgaattaaac caatagtata gtttacatca tttgaagtaa
    25621 cattttttcc atcatgccac tttgcatctt ttagctttat atctatactc attccatcct
    25681 gagctatatt atactcctta actaattgag gaattacatt gtagttctca tctatagtaa
    25741 ataaactatc ataaactaaa ttcattatat aaccaacaga cttatcagta ttagttatag
    25801 gatttatagt ttttggagtt accattgtta agtttatata cttagcatct atagaacttt
    25861 gactttgtaa acttgaatca ctactacttt gttttgtttt agtattacta caaccagcta
    25921 ccataagagt tatagctaaa acgactgtta agacttttat tctcttcatt agttttttcc
    25981 tttcttgcca tatatcttat tataatgttc gtaattattt tttacttttt ctacatattt
    26041 tgaagtttgc ttaaaaggta tatcatgtag attttcgcca tctttactat attcattatt
    26101 ttctaaccat tttttcacat tacctgaacc accattatat gcagctatca ctaaatctaa
    26161 tttaccaaat tctttgtata acttacttaa ataccaacag ccaagtctta tattagtctc
    26221 tgggtcgaaa atatccacat tttttaaatt tagttcctct gctccccaat ctctagttat
    26281 gtctaatatt tgcattaatc cttttgcttc cttttttgaa acagcagaac tattaaactt
    26341 actttcggct ttaataacac tgtaaactat attttcatct aaattaaatt ctttcgaata
    26401 cttttctaca tactctgaat attttttagg atataaaaat ttatgtatta ctttgctttc
    26461 cattaatagt gccccaaata agattataaa aatagataga atcaatactt tcttactatt
    26521 cacgccaatt ctccttcatg tactcaataa atttatgtgc tttactttct aattcagtta
    26581 ttgttcccga attatctatt atataatcac catatttgga tttttcttcc tgactcatct
    26641 gtgaatttat cctactaagt gcttcctgct cactgcaatt atctctcttt tgtattctac
    26701 taatttgtac ttcttgttta caagtaacta ctaatagctt gtcaaccata tctaaaaaac
    26761 cactttctac caatattgcc gcatctaaca ctactatatt ttcgcctttt tttctcaatt
    26821 tttctatttc acttattatt ttttctctta ttcgtggatg agtcaagtta tttaattcct
    26881 taagtttttc ttcatcacta aaaactattt tcccaagagc ttttctattt agagttccat
    26941 catcattttt tatactttgc ccaaaatgga caaatacttt ttccaataac aacttatcct
    27001 caaatatctt cctggatata atatcagcat ccactatagg aatgttaaga tttctaaata
    27061 tatttgatag gctgcttttt ccacagccta ttcctcctgt aagtcctaat atcaacataa
    27121 aatcacctac tttgtctcat accaagaact acctacattt aaatctacat ctaagtgaac
    27181 atccatattt acagcatttt ccatttcttc ttttactatt ttcttaacta tatctatttc
    27241 atcatcaatt gcttcaacta tcaactcgtc gtgaacttgt agtataagtt ttgatttcaa
    27301 attgttctct tccaattttt tatgaacatt tatcatagca atttttatta tatctgctgc
    27361 acttccttgt attggtgcat tcattgcaaa tctctttcct ctatttcttt ccataaaatt
    27421 gcttgacttt atttctggta tatatcttct tctgtttaaa attgttacag catatccatc
    27481 ctcactagcc ttttctactg ttgtgtccat aaactctttt attttatggt atttagcaaa
    27541 ataactttcg atatattctt tcgcctttgg aacaggtata tttaaatcat cagctagacc
    27601 aaagtcactt ttaccatata taataccaaa gtttacagct ttagctgcac ctctcaattc
    27661 actagtaaca tcttccatag gaacattaaa aacttgtgaa gctgttttgg tatgaatatc
    27721 ttcatgatgt ttaaatgctt ctatcatatt ttcatcctga ctcatatgtg caagaactct
    27781 tagctctact tgtgagtaat cggcatcaac caacttacag ttatcatctg caataaacac
    27841 ttttcttatt tttctaccca tttccatttt tataggtata ttttgaagat ttggttctgt
    27901 agatgaaatt cttcctgtag tcgttatagt ttgattaaat gatgaatgta ttctattact
    27961 ttctggattt attatattta aaagtccttc aacgtaagta gaatttaact ttactatttg
    28021 tctatactca gttatcttat ctattattgg atgcttatct cttaattttt ctaaaacatc
    28081 tgcattagtt gaatatccag ttttagtttt tttaattatt ggaagctcta atttttcaaa
    28141 taatataaca cccaattgtt ttggtgaatt tatattgaat ggctctcctg ataattcata
    28201 aatttccttt tctaatgtag ctattatttc tttaaattca acactcaatt catccaatat
    28261 acttttgtct acttttatac cttcatactc catatgacct aagacttcta ctaaaggcat
    28321 ctctacatga taaaaaagac catccatact catatccatt agacttcttt ccatcatagg
    28381 aactgtttct ttaactgtgc atattatttg acccatatac tctgctaaat cctcaaattc
    28441 taaatcctca tagtttttag atttaacacc ctttcctaat aattcttctt ttgatttaac
    28501 cttttttgat aaatacttca tagctattgc actacaatca tatgaggtag atgaagttga
    28561 atctattaag tactcagcta ttgttatatc aaaatacata ttttctaagt ttatattata
    28621 tggttttaaa gatatataat catcttttaa attatatcca tactttttaa tttcattatt
    28681 tgaaaatata ctatctaact ttgacacttc atttgaatct acataatata ttttttctcc
    28741 atctacactt ataaaaatat atattatatt tttttcaagt atattacctt gtcctctaac
    28801 agtttttaaa ataacttgtc cttttttgtt tacttcatct ataaattttt ctatatcttt
    28861 taattttaat atttctattt tttcttctac gtgttctgtg tcatctgaat cgaccaaatc
    28921 aactaatctt gataagagac ttgtaaatcc aaagtatcta aatttatcta aaagttcatc
    28981 tttatcataa tcgccaaaaa tcatactatc taaatccact tctattggca catctcttat
    29041 aattgttgca agtcttttac tttgaatagc tatttctttg ttttcctcta ttttcttttt
    29101 tacactacct ttaagcttat ctgtattctc tattagattc tctatactag aaaactcttt
    29161 tataagcttt atacctgttt tttcacctat tccaggtact ccaggtatat tatcagactt
    29221 gtctcccata agacccttta aatcgataaa ttgtgttgga gtcatctcgt atttttcaat
    29281 tacagaatta aagttgtatt cttcaacttc tccaactcct ttttttgtta taagagtagt
    29341 tgtattgtct gaagcaagtt gaatagcatc tttgtctcca gttactatgt ataccttata
    29401 tccattttct tctgcttttt tagaaacagt acctataata tcatctgcct catagccatc
    29461 tatttccaat ctatttattc taaatttatc taaaaggtct tttaatggct gtaattgttc
    29521 tgccagttca tctggcattc cctttcttcc agccttatac tctttatatt ctaaatgtct
    29581 aaatgtaggt gcttttctgt caaatgctac acttatatgt gttggtttat atatatctat
    29641 cattttaaat agcattgttg taaatccata tattgcattg gtctttagcc cttctttatt
    29701 attcatttct ggaagagcat aaaaagctct atttattatt gaatttccat ctattataat
    29761 taattttttt tccaaattat atcactccta aaaattatct atttttgtaa catatatatt
    29821 atataccaat atactgttat ttaatattcc cataataata atagtatatt aaaattaaat
    29881 atgttgcaaa caatatattt ttttgctata ataatataca tgacatgccc gagtggtgga
    29941 attggtagac gcagtggact caaaatccac cggactaata ctccgtgccg gttcgagtcc
    30001 ggcctcgggc accattaaaa actcctaaag ctatttattc aatagattag gagttttttt
    30061 atttttgatt taaattttaa gttatttttt gaaattactg tgtcttttta aaatttatat
    30121 aattatataa atttatcttc tagcattaat ttaaaaacta atttattttt atataatttt
    30181 ctattttata tcataactta ttacaacttt ttatctaatt tattgtatac aacaacacta
    30241 caaataaatt gaaataaaat aagcaatcca agaacaacta aaacccactt gcttattacc
    30301 attacagaaa atacactcaa tatagaaaca ataaatataa gaattacaag aacataggac
    30361 atgatttgat tagtgatacg tccagcttta tcacgtaaca taattcgtct ttcatcattc
    30421 atctctatcc tttgattttt tatcttttct tcataatcta ctgctctttc aggtttactc
    30481 caatacatat attgaagaat catacataca cctggaccta aagcagctcc agataatccc
    30541 caaataaaag cctcaaatga aaactcagta aatgtagcca ataaaacaag taaaattcca
    30601 caaataaaat atataattcc aacatataac atattctttt tcatttttac tcctcctcat
    30661 aaataaatat ttcttcaata ctcatatcaa agtatctagc tatcttaaag gctaagatga
    30721 tagaaggatt atacctacca ttttctaatg aacctatagt ttgtcttgat acttgcaaaa
    30781 tagaagcaag ttcttcttgt tttatgcctc tttcttttct tatttcttct aatctatttt
    30841 tcacatctat ccccctttaa tatctcaact acggaaagtc tactttccat aattatacaa
    30901 ctatattcca tttatgtaaa gcttactttc catatttaca aaaaaataac agactatttt
    30961 cagcctgtaa ttttagaatt tcatgttgtt tattaatttt aatgttattt attaattcca
    31021 tattatttat taattttaac ttggtttctg aattggaatc caaacttctg tagtataatc
    31081 aggagcattg atatcgccat tgggataaag ttcaatatct ggtaaattag catacacata
    31141 cccagaactt ggtaaccact cagtaataat tcttttttgc aattcctgta ttgccagagc
    31201 atttggcatt ggagaaacac attcaaatac tgcccatgtg cctgatggta ttaagtattc
    31261 atgagtatct tctaatacag gcttatctgt tggagcagca atataataat ctaaaccctt
    31321 actatttgta cacacactaa ctccaagcaa tccacaaggt tcattattta ttaactctga
    31381 aagtttatca attgttccat tttttatgca tttagcccac aacttaggaa ctttctcaaa
    31441 gcactcttct acaatcatgt tcatactttc ttttatacca acaatacgaa accctttctt
    31501 ttctacaata cgatattgca tttctatatt tccttttaca taaatgctta atgtcatctt
    31561 aggatatgct tttaaaacaa caccctttgc tctagctgca gatggagaaa tgttatgtat
    31621 attttgaaaa gctctattaa aagatgttgg tgaatcgtaa ccatacttct cagatagttc
    31681 taaaattttg atgttactgt tctgaagttc aaatgcagcc ttagtcatac gtcttcgtct
    31741 aatatattca gataatggta cttctgcaat atatgaaaac attctttgaa aatgaaaggt
    31801 tgaacaacat gcaatttttg ctgcttctgc ataatccact ccactttcga gattttcttc
    31861 aatataagta atagcttgat ttaatttatt tatccattcc atttgatatt acctccaagc
    31921 aaattataca gtttaataaa ataatatacc tctctattca tgcacaaaat tgtaagcatt
    31981 taaatttata agcatttttc aatcaataca ataaatataa aaattgtatt atacaataaa
    32041 aaagttcaat aacattatat tataaaatgt tattgaactt tttataaaaa ttaatttaag
    32101 tgtagttaaa ttaagtatta cactatctta tatattacaa tatcctacta tcttatagtc
    32161 ttctggcact ttataatctt tgtctggagt acctaaattc cattttaaat caaacatagt
    32221 tgcacttatt attgttgcaa aataaagcat aactatacca atgtctattt tttcttcata
    32281 taaattagta tgaccatctt ttctaacagc taaaactaca gtgcctccat caactataaa
    32341 tctccatggt tgtctattta atgtagatgg agctaatctt gcatagtgaa atgcatcaag
    32401 aagtgctctt tcttctaaga tttctatact tgcaacattt ccccattcgt tcatataaac
    32461 aacatcttct acacctagtc tagtagaccc cttatctgtt acaacttgca tatcagattt
    32521 tgaataattt tgcccagttt ttgtagcatt taatacttta gcattactta cattttctcc
    32581 atatccaata gctataattc ctgttacctc tttatctgaa ttaattccaa gtttttcttt
    32641 tacctttttt ccatcttcaa aagtaaccca acaagaacca attccaagtt ctgttacttt
    32701 aaagattata ctttctccta tgtaccctga attttcaatg taattatctt ttatgtcaga
    32761 taatattata atataacttg gagaatctat catatttcct ttgtaccctg ctactttatc
    32821 taaattatta aaaacttcac ttctattcat aattcttaca tcaacatcta tttctggaac
    32881 tagtttctta caagattctg agtatttctt aatttcacta agatattctt ctttaatatc
    32941 tgtgttctta tattctctaa cagactttct atttaatatg attgttttat aatccataat
    33001 tttatcctcc ccaaactagt attgtcttaa ttatataccc attaatatat tattttactc
    33061 atttatttaa taaataaaga ttacaatttt gtaattatta tttattaata atattccact
    33121 tttacattaa taatgaccag ttgtgcaaaa tccattgcca accaccaaat aaaaacatat
    33181 tataaaggta atataaaata acaaacaaat cttaacaaaa aattaaactt tttttacacg
    33241 aaagaaggct tcccgttgcc ttctttattt ttataaaaaa ataagctgtt tctaaaatga
    33301 tttcacattt ttgaaacagc caagttattc tataatgaca actataattt gaggatgtga
    33361 gggagagttg tcattataaa tttagggtaa ttatattatg ttttaagcta gttctttcta
    33421 tatttatata atacatttta tatatgaatt ttatatgaga ttggtataaa tgatatatga
    33481 aattacatat gtttatatta tattaaattt tattattaca ttttccacaa caatactcat
    33541 atgtctccac attatttgga atatttacaa atacaaattc tttacagttc tcacaatact
    33601 ttaatataga tatagttcca caagtgtaac attcaaatat tacacaatcc tcattttcct
    33661 ctactatttc aaacttttta ctatgttcac cacactctgg gcacttgtga ttatttacat
    33721 tcataaatac tcctccttat tagtatagtt acatgtcaaa aacttaatta atgtattcta
    33781 tattacttat tatatattct ataataaatc atattctaat ataataaaac aaattaaata
    33841 aaaaaaaacc ataaatttta aatttatgga ttaattcttg taatgataac tctatttgag
    33901 gatgtgaggg agggttatca ttacaatagg gtattatatt atggttttta agctagtctt
    33961 tctacacctc atatgataca tatgctatat gaattttata tgatttttac ataaatattt
    34021 tatgaaattt aaatttttta gtcattttga aatttgtaaa aagttctcta aaaatccaca
    34081 gcatcataaa cagccaaaat ttaagtagaa catcataaaa aaatttgtcc aataatttta
    34141 acaagtaatc tcacctcatt ataattattg acacaaactt aaataaacaa tctataaatc
    34201 ttctataaat cttaaacttt ccccctattg atacacaatt tctagtttgt caattttatt
    34261 ttgcatttct aagaaaattt cttcaacaga attgttaaat atattgccta aatagattct
    34321 tttatctttt tgaaatgaat aagattttac actaccatca gaagaaatat ataaatgact
    34381 ccactctgct ccatattttg aaaacctctc ctttgtatct ttaaacctca tatcttctat
    34441 ttttattgct ttttctctgt ctcctcttac tacagtgtga ccccttttta ttaaactggt
    34501 tatttttata tcttctttta atttaatacg tgtatcatca ttttttgaat atactttcca
    34561 tatcacttta tgacgataat tatctaattc ctttattaag cttctatcaa tagtaaaact
    34621 atctttagtt accacaatta aatcaaaatg gtctaacata tattgaaata tttctctcat
    34681 acttttattt tttaaaatat cctcaccaat aacctctata aatctacagc ctttctcata
    34741 catgcagttc aataaacttg tgatttcaga aaaataatca tttgtattat tatctccatc
    34801 tatttctata gtaaagtaca aaggagtaat gtatgattta tttcctgtta tctcaaatac
    34861 acttgatagt gtctgtatat catcttcaaa cgttaagtat acattctcat aaaacataaa
    34921 aaattccata actttttctt tcatattatg gatatttcta tatctattgg ataatatatt
    34981 tattatatcg tcagtagtat ttttcccatc acattcagcc agtataacaa tttgcttcca
    35041 acttaagcta tccacatttc cgatactttt tttatatcca tcttcttcat cataaatagg
    35101 accaattata atgttttctt ttggccacag atgaacccta gttccatctt ttaatttcgg
    35161 atatttattt tttacagact cataaaatct acttgtatca cccatgattc tttactaccc
    35221 cccatagttt aaatattcta tgctaaaaat agcactttat ttttattaat tcaacaatta
    35281 ttcaaaattg gtcattatat atgtttaaat ggatttaaca tcaaccttat ttatatgtta
    35341 ttgatgttta tatatgttat ataaaatctt atttctcata cttcaatgta atcttaacta
    35401 tctctggttt acaattaagc ctaattaaaa cttttgagcc tcctaagcct ttatttaaaa
    35461 tcatagtgct attatctttt tcatattttc cccagtcata cttaggaaag aactctctat
    35521 ttggagataa tacacctcca acaaaaggta ttcttattat acctccatga acatgtcctg
    35581 ctaaaaccaa atctgctccc cattttgcat atttttcaaa gaaaaatggt gtatgtgcta
    35641 aaagaatgtt atattcattt tcattaactt tacctagatt gtcttctaca aaattgtcac
    35701 ttagttctaa ttttttgcta ttagcaaata aatatggata gcattccaat ggtataatta
    35761 aaccatataa attaagatgg ctattacctc tatatattct tacagattca ttttccatat
    35821 ttattatttt ctttgaatat agttccttaa aataatcctt atatagatgt ttatactttt
    35881 ttattaaaga tttttgttca tgatttccaa ttatatgata tacttcatat ttttcaacca
    35941 aattatctat taaatctaat gcaacttgaa aatttttatt ttctccatct actaaatctc
    36001 ctgttataaa tataacatct gggtttaatg attcaatttt atctatcaat accttattat
    36061 ttttatcaaa caccttatta tgtaaatcac tcacttgaac tattttaaag ttatcaaatt
    36121 cctttggaat ttttttgttg aaaatagtat attctgtcgt ttctatatgc tgagtttcat
    36181 acttatacag aatatacaat aatattaata ctaatactgt cattgaaacc tttataatca
    36241 tattctcttc ctctttattc tattttgtta atattattat aatgctttta tgtttttttt
    36301 aaaacaataa catcatcaca tacatataaa tcttttcgac attataaaaa taagttatcc
    36361 ttttctaaaa ttttcattta ttttagaaaa ggataactat aaaattatct ataaacctct
    36421 atattgtgaa atatagtttt tcctttattt aaatttttat atatatgctc taaagttcca
    36481 tcaaacctaa tagaatgtcc agactctaaa atataagttt tcccatccac attaaggtca
    36541 agtttacctt ctattacgag tacatactct tctaaaacat gactgtgtgt agatgaaaca
    36601 tgagtacagt tttcctcaag ctcaattata aaaagttcaa accttctttg agggctaaaa
    36661 gggtatattg gatataactt catgttccct ttttgctcaa caataggctc tacttcttct
    36721 ttctttataa cctcataggt atttgtattt tcatttaata gtgtagtaaa atttatttta
    36781 aatccagatg aaattttcca taaagtagat actgtcggac ttgattcacc tctctcaatc
    36841 tgtccaagca ttgctttact gacacctgtc atctttgaag ctttgtctaa acttatgccc
    36901 atttcttgtc tcaataacct taaattttct cccacattag gaaatttatt atccatgtta
    36961 aaatcctcct gatagctatt tgtattctat gatttttact cctgtaagtt ctactatctc
    37021 ttttaatttt aacatatgat tgttacaaat ttcatcaaat tcatatatat aatcttcaag
    37081 ccctaatgcc ttatatttat cgattccaaa tttatgatat ggaagtaact ccatcttgcc
    37141 tcctggaaca ttttgtttga caaataatgc agtatttctt atattttctt cactatcatt
    37201 tactccataa ataattggca ctcttataac catagattta ttcaactttg aaagcctaca
    37261 tatattatct aatataattt tattacttac tcctgtatat tctttatgaa tattatcatc
    37321 catagatttt atatctacaa atatgtggtc tattttctca aatacatcat ttaccttatt
    37381 ccaatcaaaa tatccacaag tttcaattgc aatatttatg cctttatcat aaaaaatatc
    37441 aactaattct cttaaaaaat caatctgaag tgtaggttca cctccagaaa aagttatccc
    37501 tccattagat tcaaagaaaa atataaaatc tttttcaact tcctctacta tttcttcaac
    37561 actcatttct tcggtcatta tacaaatggc atctttaaga cataccttga tacactctcc
    37621 acataaatca catttattat ttatttgcgc tctatcaaat agtgaactta tattttgagg
    37681 acaaacatct atacatctat tacaggatac acatttatct ttcataacac ctaattttac
    37741 tatgttactc caggaatctg gattagaaca ccacttacat tttaatttac atccttctaa
    37801 aaatatagta gtccttattc catctccatc atttactgaa aaatgttgta cttttacaac
    37861 tctacctttt ttactcataa tctacctcat aattaaaaat tgctatgtga atttctagct
    37921 attatagcat cttgcatttc tcttgataaa ttaacaaatt gagtactata tccagcaact
    37981 ctcactaata aatctttata ttcttctgga ttttcttgag cttttaatag agtatcattt
    38041 gatatcgtat taaattgtac atggaatcct cctaaagcaa aatatgattt aatcatagat
    38101 gttagatttc taagtcctct ttcagtttcc accaaatctt gattcagtct taaatttaga
    38161 agtgttccac cagtatgaac atcatgattt atttttgatg cagatttcat tgctgctagt
    38221 ggacttgttg tatcagtacc aacaaatgga gaaactccct ctgtcaaagg ttttgtcgct
    38281 tttcttccac aaggagttgc gcctacgatt tttccagttg gtacatagtt tgatataccc
    38341 ataaatgcac tattaaattt agagccaaaa atatccttgt attttctagt ttcagtataa
    38401 taaaaatcag aaacttcaat tgctaatgaa tctacataat cattatcatt tccatactta
    38461 ggaacatcca acgcaagttt tcttaattct tcataacctt cccaatcatt atttagtgct
    38521 tttgttaatt cttctaacgt agtcacctta tcctcaaata ctaatttttt tatagctgcc
    38581 aatgaatttg aaactacacc taaccctata ccagttaata caggacctat attatatttt
    38641 gctcctcctt tacttaaatc aactccctta tccaaacatc catctacaca agtagataaa
    38701 aatggtcttg gtaccatttc tttatgaatt tgttgagcaa cagtagttcc tataacagaa
    38761 ctttttacaa gatatgctaa ttgctttaaa aactcatcct taagttcttc aaaagaagta
    38821 aattctgtga tattttttgt atctaacccc attttttctc cagttaatct actcttacct
    38881 tcattcatag catattctaa agctgctgca aaattgatat ttacggctga agtccactgt
    38941 cctgtttttc taaaatgagg aactacacaa ccacagttac tccaatctct agcatcttct
    39001 gcatcatatc catcttgtaa taacatttgt gcccctgcac tatcgctgtg tatagcaggg
    39061 aaaccagttc cttgttttac caatttagca actgccatta cgaaattgtc tggtgctcct
    39121 tgactcactc taacacttaa tcctggttgg tgagttttta cactttctgt agcctttaaa
    39181 cacatatatg agatatcatt cgttccatca gtaccatttc tctttttacc accaacagta
    39241 agattttgga attgattata tcctgcaaag taatttgctg tatttgctga tatagtccat
    39301 acccattctg ataacttaat ccaaagtgct tctatcaatt cttgagcttc tgattcagtt
    39361 attttacctt ctctagcatc attttcataa tatggataca tatattgatc aaatctacct
    39421 aaatttaatg ccaatggatt ttctgataga ataccaccta attgaacaaa ccatacaaat
    39481 tgtattgctt cataaaaatt agttggaggg tttgctggta cattcataca tatctctgaa
    39541 atttttataa gttctaactt tctcttttca tctgtttctt gcttactcat ctcttttgca
    39601 agatttgaat atctttgtgc caatgtcata ataccctgtg caactataga aacagatttg
    39661 taaaaatcta tcttttcaat attttctgaa actgatatat ctaattcttt aattttttta
    39721 tctgcatctt ccttaatccc tttatatcct tttacaaaca atatatcttg ataatctggt
    39781 gttacttcac caactgcctg tctccactta gaatcattat ctattattcc tgtatctact
    39841 aatatcttag ctgtatcttc tgggattctt gctaagaaaa cttcttccaa agattttccc
    39901 ttccaatatg gaaatatttc ttttcttata aattctattt gttcttttga tattacatat
    39961 gggtcttgag ttcttttatc aaaagtatcc atttctttgt ctacccattg ccaagaaaac
    40021 tctggtgtca atatccctgt tcttctaaat tttcctgctg tacctactat taattcattt
    40081 tcaaagattt ttataggaag ttctttacat gtctccaaaa aagctttagc tcttcttata
    40141 cagatagctt ctccctcagt ttttttatgt gattctgtaa aaattctagc cctttcacaa
    40201 catatcatag gtttagaatt aatatattct tgtctaaatg cttctattct attagtttga
    40261 ctcatttaaa atcccccttt ggataatata tactacattt ttgtatgtta taacatactt
    40321 taattatatt atactgtcct ttagcataaa atggaagcaa aataacttat tttttttcat
    40381 ctaccttgaa cacctatata ttaatacttt ttttgttaaa tttataaaat ctaaaaaaat
    40441 tttctatgat atattttcta tattgttata gttatgtcta atatactaat gatttgaaat
    40501 atcaaatttg tatactagac ttagttttaa aaccttagtt gattgtttaa ctttgttaac
    40561 ttcaacatgt atatccttca tataaggaag ctctacaaca cctactccct tattaaagtc
    40621 ttcttcaacc atagaaaaaa tttctttctc agttaagttc gtatcagtca atgatttaaa
    40681 taaattgtat ataaatttaa catatttatc actctcagat aacttatcat cttctggata
    40741 ctctttagca cagagaatat ctattgttac ttttccttct ttatcgtctt cagacataga
    40801 atagaataaa cttcgaatat ttttttcagg tggtttttca gcaccattta tagatactac
    40861 aaagctacca tctgattttg agttagtaat actataacca ctgtctatta tagctttcga
    40921 aaatctttga gataaatctt tttttacttc ttctctacct ttcgcatcat taatcttttg
    40981 tgagtaatta ttaaatagct caatagattc atctttttta tcttcaactt gttctttcaa
    41041 tgaatcttta ctaatttgtt ctgagctact taagttctta tcagatacag gagacataca
    41101 ccctaccatc aatgctaagc taagatttaa agccacaatt attgccactc tatttatatt
    41161 cctttttact ttcatacaca atcctcccat cacactaacc gctctaaagt attattcatt
    41221 gcactagaat atatttatat tttctttata ttaaagattt attattcaat acatatcacc
    41281 ttcctatcca attcttataa cttactatta gtaaaattat aagctcctta atacagaaat
    41341 aaggatgtta tcttttgtta ttaaaagata acatccttat ttttttgtat caatacatat
    41401 gtcccaactg gtaacttaat cgccccaact gtcagtatct tggtccaatg gtatatatat
    41461 atttagtata aatttatcga tactattttc aaataataat tctccattat atttttgtaa
    41521 agaagattta atactctgaa tacctattcc atgtacgaac ttatccattt tgtttgttaa
    41581 caatatattt ttattaaaag taagctgatt tagtttacta ttttcacatt taagtacaaa
    41641 aaatgacctt gttatagttc ctttaattct aatatattta ttaatatttt catccactat
    41701 tttatcacat gcttctattg cattatccaa aatattagaa aatatgcttg acacatctat
    41761 aggttttaca aaatttactt ttgaaaaatt tatagagcaa gtaaatttaa ttcctttttt
    41821 taaacatact tcactctttt cgttgattat aatgtctaat atcatatttc ctgtattata
    41881 gatatattta aatgttttta tttcatcttt taaattgtta acatattcat taatttcttt
    41941 gctattgttt ctaaggttgt ctatacaata aatgtgatta tttatatcgt gatatagttt
    42001 cttaactcgc atatgagatt cttgaatact taaataatgc gcatattgca tatctaactt
    42061 attttttatt aattcagctt gagattttaa tctattctct tttattattt ctttaaacaa
    42121 tagtataaga aatatactac tagctcctac caattttgga ttaacaaaat tatcaaaata
    42181 gtatccttct gaatgtaatg acccaaaccg ttctaatttt tttaatacat aatttacaag
    42241 catattcatt gtattaacta ataaggcaaa taataaatat acataatttc tcttatcttg
    42301 gctaattaat tttatagact ttctaaaaaa gctaaatata agatatataa gaataattat
    42361 taaattacta tatatctgaa tttttataga ttctaagtaa ggtactaata aagattcttt
    42421 agatgaaata acattacctg taattgcaaa aaatagtatt ctatatataa cagcatccaa
    42481 acatttataa tatacactaa atagataaaa gaaaatggaa tacttaatat aacccatctt
    42541 ataaaaataa ttatagtatc ctccccaagc aataaatgct aatatataaa ataaatagtt
    42601 tatattacta aagtaatttc ctccattaaa taatctactt atctgaatta taatataaat
    42661 aagaaacaag acaatataga atactatttt ttcatttttt ttactatcct ttttataaat
    42721 taaaattccg ttcattatag aaaactgtat aaatatagat aaaactacta atagctcagt
    42781 cataaagttt agcatattgt atcaccaaga aattttaaga atttctcctt aacttcttta
    42841 tatctatatc tactaatagg tacctcttct ccactttcca gtattgcagt attaggcttt
    42901 atattttcaa catatcttaa atttactata aaacttttat ggcatcttat aaatttatat
    42961 ggatttaatt ctttttctat tttgcctaaa ctatatttta tatcaaaatt cttgtttatt
    43021 gtgtgtatta gcatatcttt tttttgaact tctatatatt ttatttcatt taaataaatc
    43081 ttatatgtat tagacttatt ttttattgta atatgacttt ccttatttat ttcaatatct
    43141 ttgatacaag ttagcacatg tttttttagt tcttccaact ctattggctt tagtaaatac
    43201 ctataagctc ttacctcata accttcttgc acataatcta ttaatgaagt tacaaatatt
    43261 atttccattt cattgtctac ttctctaatc tttcttgcag tatccattcc atttaatttt
    43321 tccattttta tatcaagaag taatatatct atatctttta aattactttc cagtaactct
    43381 tctccagata tatacttttg tatctcatat tctatactta tatcttttaa tatattctca
    43441 aggtaatctt ctattaaaag ttgtgtttct ttttcatctt cacaaactgc tatcttaatc
    43501 ataaaatgcc tccttacata atttctagtt aatacaatta aaatatttat aatatattta
    43561 aagataattt tgtatatctg atactttagg ataacatttt taaattattt ttatcaatac
    43621 tcaatcccat acaactatta tttgatattt caatttaaag acagaaatta ctataattaa
    43681 aaacagtact tactgacaaa agaagatgtc ttaaaatatt aaaaaaataa ttttaggaca
    43741 ccttctttta tttatttaaa ctttttaagc cttaaataat acattaatct cctatataat
    43801 tgtactgcat ataaaatcaa caatataatc tgtagtacaa tagcagttac agatgctcca
    43861 taaccactat ataaatttct tatttcaata ttcaataaat atataaatat tactactaac
    43921 ataaagaata taaacatatt cataaataaa attgacttta ctttatttgt tttatcagaa
    43981 tcactatata atttaggagg tatgtctttg tattctttcg accatatata ccatgcagat
    44041 gtacccataa aactaccaat actcctaaat acaagattcc agccatttga tttatgttca
    44101 tcaaaataat tattctctac atcatagtag taatcaacag tgtattttat ttttcttgga
    44161 cttcccttat gaaaataaaa tattcctcca aatttattta tcttatataa attatatcct
    44221 ttagcttcaa tatcttctaa ccatttctct atcttatcag gtgaactata ccagtcaaat
    44281 ttgaatttta ttttcttttc catagcactc attctccaaa atgatatttt taaatagctt
    44341 aaaaatctat ttaaataatt atatcatttt gatactaatt ttaggttaca atcatatatt
    44401 taaaagttat ttaaatagta ataaactaat agccataaca cccattcctg caatcaatcc
    44461 ataaatagat aaatgatgtt ccccgtactc tctagctgat ggcaataatt catctagtga
    44521 tatgaatacc ataattcctc ctacaattgc aaatacaatt ccaagagtta tatcatttaa
    44581 aaaatttcta agaagtacat atccaataat cgctcctaaa ggctcagaca taccagataa
    44641 aaaggaataa taaaaagctt tctttttatc tcctgtggca taataaactg gtacagatac
    44701 agatatacct tctggtatat tgtgtattgc aattgcaatt gctatcggaa tagctattgt
    44761 aacatcatca agagctgata taaatgtagc taatccttca ggaaaattgt gaattgctat
    44821 agccattgct gtaaatatac ctgttcttaa aagagactta ttttttttga tattcttttc
    44881 ttctatattc tccattttct ttatttcatg tggattttct tcttgtggaa ttagcttatc
    44941 aataacagca atgatagcca tacctataaa aaaagctatt acagttgacc aacttcctaa
    45001 tttctctccc atagattttg tcaaagcatc ttgtgcttta ggaaaaattt ctatcataga
    45061 aacataaatc ataacaccag cagaaaatcc taagcttata gaaagaaact tagtatttgt
    45121 ttttttagca aaaaatgcta tacaacttcc tataccagta gataaaccag ccaataatgt
    45181 tatcaaaaat gcaaatatta cattattcaa ataaatcacc ttctttttaa ttgatattga
    45241 ttatcatttt ctttatgcta tcatatatat tttatatagt caatatttat aaaaaatata
    45301 cacaataaaa aagcagagat ataaacttag tctctgcttt ttctttatag tatattaaaa
    45361 ttatttattt aagaaatcca ctgcatattg cacatataaa gcagttccaa tttctagagc
    45421 atcttcatct atattaaagc atccatgatg atgaggataa caagcacctt ttgactcatt
    45481 tctagctcct acaaatgcta gtgcaccagg tgctatattc ataaactcag ctaaatcttc
    45541 tgctcctgtt actttttcaa atagtgttat acagtcttct ccaaatagct taattgctgc
    45601 atctgtagct atctttgaac attctttgtc atttataact gctggtgtta agtacccata
    45661 ctctaattca gcatctgctc tatatgcttc tgctgtagat tttgctatac gttctaaaat
    45721 tccaggaatt tgctttctaa gctctggatt aaatagcctt attgtacctt ctaagatagc
    45781 ttcactcgca attacattaa atctagttcc agaatttaaa actccaacac tcacaactaa
    45841 tggttccaga ggacttactt ctctactaac catagattgt agattcataa ctattgctga
    45901 acttgcaagc actgcatcaa caccttgatg aggaagtgaa ccatgaccac ctctaccttt
    45961 tacagtaatt ttaaagaaat cagcagaagc cattcttggt ccttcttcta ccgatatggt
    46021 cccagattct acatcagtcc aaagatgtat tccaaacaca ctatctacac cttccatagc
    46081 accatcttga atcatagctc ttgcaccttt accaacttct tctcctggct gaaaaaataa
    46141 ttttacagtt ccattgatac tatccttaat atcatttaac acttttgctg cccctagaag
    46201 cattgatgtg tgaccatcat gaccacaagc atgcataagt ccttcatttt tagatttgta
    46261 ttctacatca gtgcattcaa caacttgtag agcatccata tcacccctaa gtgctacagt
    46321 ctttcctgga ttatctcctt ttatagttgc aattacacct gtacctccag ctgatacata
    46381 tggtatccct attttatcaa gttcttcttt aactctcttt gatgttctaa cttcttccat
    46441 acttttctca ggattttcat gaaattccct tctaagctta attacatagt ctttataact
    46501 ctttgttatt tctttaatat ccattctata cctccaagta gtacacattc ttcttattta
    46561 aaatactttt tatcaattaa atactatatt agatttacaa agatacctgc tattactaca
    46621 gaagctattg taactgtagt aaatcctcca acaagcatct ttggaagcat tttatccatt
    46681 aaaaattctt tttcttctgg tgtttcagcc aaagccttta ctgcctcttc agttaatata
    46741 tagtttggtg gaaaaccata aagtgatgta agcgaaactg aaaaagccat ttctttactt
    46801 tcacctaaaa gcttacctac tataatagag aaaattccca tacctattac accaaatatt
    46861 atgattccta caagaggaac tgccatttca acaagcattg ctggtgtagc ttttgctaac
    46921 cctgcaaata taaaagccat caatgatgtc attaaccatc caaatgaacc agatttatta
    46981 agtggttttc tatcaactat tccaagttct gatgctatta caccaaatat taaacatata
    47041 acatatcttg atacaacttc atttgtaaga tttgtaaatt gtactgctaa ccatgctaca
    47101 aatcctaatc taagtattat catatatgtc gtatcatatt tttctggtaa gtctggtatt
    47161 atcttaaatc tgcttttttg ttcaggtaaa tccttaactt tttcttcatc tgtatttaca
    47221 gttacttttc cacttctaaa gtctgataaa agtctttttc cttctttttt aagcattaat
    47281 gctgtaatag gataacccgc aaatccttgt gcaacataca tcaaaattgc aagtactgat
    47341 aaacttgcaa gaccttttgc tgtagcagca tctgccatca ttatagatgc aactagccct
    47401 ccagtaagag gaggtgtagc tattactgct gtatcccatc caaatactac tgtccctaat
    47461 gccaaagcac ctacacatat tcctactatt cctgccaagg ctattactat tgttttccat
    47521 tgacctgcta attccttaat actcatcata gttcccatat gagttattaa caaaagcata
    47581 cctaattgag ctaatggtgt tcctaaagcg gctaagtcca caatattttc tgggaaaaaa
    47641 gtccaaaatc ctactataaa tataattgct gatacaaaaa ccgacggaac aaaagcttta
    47701 gtttttgctg aaactatatc tcctatcgtc agtgatacta aaactagaca aaaagctgtt
    47761 attgcctcca tacaaaatcc cccctcataa taaatatatt tttataaaat gtatgtatag
    47821 ttatccatta ttttactact tttgaaaaac atttcaagtc aaaattcgat ttttttcata
    47881 aaattcgata aattccataa attaaagtta gttttctaaa ttattctttt tgtaaaaacg
    47941 ttatcccgac cattggctat ttaactctat tcttacaaag agaattaaat gtaatttgca
    48001 aaaaataaaa cataggatac attttattca taaaacatct tataaatata aaatgaattg
    48061 tctttatgaa tcttaatata tcctatgttt gtaagtttaa tgtgtatgtt agctatggtg
    48121 taaaatttgt atactagtta ttgtgtaacc tactatatac tccatttttg tttactagct
    48181 cttcatgagt acctctttct tcaattcctt tatccgtcaa tactatgatt tcatcagcat
    48241 tttttatagt agtcaatcta tgtgcaacaa ctaaatttgt tctatcttta cttaattcct
    48301 ctaaagactc ttgaatttct ctttctgtta cattgtctaa agcagatgta gcctcatcca
    48361 atattattat tggaggattc tttaaaaaga ttcttgaaat tgaaattctt tgtttttgcc
    48421 cacctgataa ttttacgcct ctttctccta tataagtatc atatccatct ggcaaagtct
    48481 ctacaaagtc atgtattcta gcttttttag cagcagctat catttcttca tctgtagcat
    48541 tagggttccc acaaagaata ttatctctta tagttcctgt aaataaaaat acatcttgtt
    48601 gaactatacc tatatttttt ctcaatgatt ttaaactaac atcttttata ctctttccat
    48661 caatttttat atcaccctta tcaaattcat aaaatcttgg caatagatta cataatgtag
    48721 tctttcctcc tccagaaggt ccaactaatg ctatagtctt accagctttt atagataaac
    48781 ttaaattatc caaaacttga gtcttatctt catatgtgaa agatatattt tctatctcaa
    48841 tgtcaccttt tacattttca agttcaatag gatttttagc ttctttttga tggtcttgtt
    48901 ccattatctc tatgaatctt ttaaaacctg tcataccatt ttgatattgc tctgtaaagt
    48961 ttattaattt tttcataggt tgtataaaca tttttacata tagtatataa gcagcaaaat
    49021 cacccaaagt aatctttcct atataagtaa aataaccacc agctattaca actacccact
    49081 ctaagatatc catgtataaa ttcataccag agtaatattc tgccattacc ttataagaat
    49141 cttgtcttgc tcttctaaat aatttattgc ttcttacaaa cttatttaac tcttctttct
    49201 cagtacaaaa agacttagtt accttcatac ctgctatact attttctaaa gtagcattta
    49261 catcacctat agtaactcta ctcttcataa aagcaatatt catcttatct tttttagcta
    49321 ttgcaaacca aattataaac ggtaatatag caaatattat aagcgtaaga ggaatattta
    49381 tatctataag tataaagaat gaaccaacca acattactat agaaatgaat aaatcttcag
    49441 gcccatgatg tgcaagttct gttatatcca ttaaatcatt tactattcta gacatagtta
    49501 ctccagattt gttattatca aaatacgtat ttggaagtct ttgtaagtgt gtaaatacct
    49561 catttctcat atcagcttgc atatctacac caataacatg tccccaatac tgcataaaat
    49621 agttaagccc tgcttttgct ataaatataa gtataagtgc tactgcaaaa actactaaca
    49681 ttcttaagtt tttatttgga acaacgtcat ccattatatt tctagttatc ataggataaa
    49741 ctaaatcaca taaggaaaat agaaaagctg ctataaggtc tagtgtaaaa attttcttat
    49801 atggcttata atatttgaca aattgtttta tcataagtat taaatccctc ctttattagt
    49861 acttctaaaa aatacccata aattagtata acataacaat aactttaaat cttttataaa
    49921 cttacaaagt aataacaatc tttttcataa aattgaagat ttatatcata tagttgtata
    49981 cttgaaacaa cataaaaaga gctatatctc tatatttaaa attttataaa gatacaactc
    50041 tatatttaat actaaatttt ttttataaat acaaaactac ttcaatgcat ttaatatctt
    50101 tttatctaat gctgttgtat ttatacctgt tatatatcct gttgccttta ttgtaggtat
    50161 atcataagtt gttggtagta tagtagtaga tacgattaaa tcagcacctt cttgttttgt
    50221 tgaacattca gcaattttac attgctcaac ttctgcttgt atattatttt ctttaaccaa
    50281 tctttctact ctgtcacaaa ctattgttga tgttgcgatt cctgctccac aggctactaa
    50341 tatttttttc atatattgtc ctcctacaat ttctttaata ttttataact caaaataaaa
    50401 ttgataaatt tcttatatct ttatttatat aaataattat atcattttat ataagaagaa
    50461 catcttaaaa ttattctttt aatatgtttt ttatttcaac attgcttata cttaaaattt
    50521 cattttttat acaagactct atgtactttg atatattttt ataatcattt aaattaaact
    50581 gttcaatatt caatttatat tctatatcac tgacaatacc tatcaaatca gacttattag
    50641 ataaaatatc ctcatactta ccttttctag ttacttccaa tcttttaaat ctataatttt
    50701 tatatccttc tatgataatc aagtccatat cttcatataa ttgaatcatt ttatataatg
    50761 gattcttctc ttttagttct tcaatatatg ctactcgttt atctgatatt atacagactt
    50821 ttctcgcccc agattttcta tgtttataag tatcttttcc ttcctcatcc atatcaaaat
    50881 catgacaggt atgtttaata actccaacac gatacccttt tttatttaat tcttttatta
    50941 tgccttcaat caatgtagtt ttacctactc ctgaatatga gacaactgac aatatattat
    51001 acataaaatt gtgtcctttc ataaaactat ctaataacaa catccactaa ttgattttct
    51061 tttattgtct cattcttttt aatcttaatc atacaattac ttcttagagt tgcagataat
    51121 ctagcttttg catctttctt atcatttagc tctacataca atttaccttc acttgtatat
    51181 agttttccac ttacaaatct atctttattt gaaagtttat taaattctcc tttaaatata
    51241 gcttttatat gatgtgttcc cttcttatat gttaaatact caataacagg aactatcaca
    51301 ttatcaaata ccactattgc tgcatgtgga ttaccagaaa gaccaaataa tagcttttct
    51361 cccaatgtac ctacataaca agctccacca ggtttaatgt ttatcttcca aaataattct
    51421 gttgccccta tttttttgaa tacatctgga attaaatctt tatctccaac agaaacacca
    51481 cctgtggtaa ttaaaaaatc tacactctgt aacatattct ttaccttttt ttctaactcc
    51541 aatatatcat cagaacaatt gcatattgta tctgcttgta ttccaagttt taataatctt
    51601 gaatataagg tatatctatt actatcgtat attttaccat tctctaaagt ctcatttata
    51661 tcttgtagtt ctgtacctgt attcaaaatt ccaactttta aatcatcata aacagttact
    51721 ttggatattc caagacttgc taatactcca ataccatcat atcctatatt ctgattttta
    51781 ttaataatca attgcccctt ttttatatcc tcacccttaa atatgtaatt atcgtattcc
    51841 tttaatttta tatttaaagt tatcatatca cttataactg ttacatcttc tttttttatt
    51901 acacaatttg caccctgtgg tatctttcca ccagtcatta tcttcactgc ttcattttta
    51961 tttaataccc tattaaatac atctcctgca tacaaagtcc ctataacctt taaatttcta
    52021 ttttcagaat ttgcattata tgcataacca tcatagggtg acctatcaaa tggaggacta
    52081 tcaattgttg aatatatatc ttctgcaact accttattta ctgcatctat aagatttact
    52141 atcttgaccc tgtttattgg taaaacattt ttttcaataa tttttatggc atcttctaat
    52201 tctatcattt taaatactcc ccaatatatt ttttatttaa gatatttcta tgtaatatat
    52261 tatagattat aaaagttgga aatactttta tcttatattt aattataact aatagttatc
    52321 tataagtgca gttcaaattt tataaatcta ataaaaaaac tgttcccagc tagaaatttc
    52381 cttctatctt gaaacagcat catatgcttt agaatatttt attctaataa agttcctttt
    52441 attattttta caattttatc actttcaata gtttttatag attttatttt gttatccaca
    52501 atacttattg taagtacctc tttttttaat attttgttat cttctttcaa tctataactc
    52561 ttaactactt tactgccttc atgattatat gctgttaaat cataattcgc atctcctaca
    52621 atttcattta ttctggaatc ttcaacacca acatactctc ccaggtcaat atgtctaaaa
    52681 ttttctagtg atacagccga tttttcatgg tcactttttt caatcactat actagattca
    52741 gcatcaatga ctgatatacc ttgtgatgag aaagaattgg tttcaacatt gacaacttta
    52801 ttttcgttaa tatcaacata taaagcactt ccatctagtt catcatttcc agtatatttt
    52861 ggataaacta atgtcatata acttgatgta tttatatctt gcattgtatt tgattctttt
    52921 aaaactttag gttttatata ataaaatgta ttataaggta tacccatatt ctttataatg
    52981 tacttataat ctttattcat aatttcatta acatcatttt gaacttttgt catagttttt
    53041 tgctgtgttg ctttacttgc tacttgattt ttctctttag tattttcttt atgacatcca
    53101 acaagtataa tacctaaaat agttacacaa actaatgacc tttttaactt cataaatcaa
    53161 tcctcctttc ttaaatttta tagtatttat ctatatctca atttacagtt atctc
//
LOCUS       DAYAOO010000020        50902 bp    DNA     linear   BCT 12-OCT-2024
DEFINITION  TPA_asm: Clostridioides difficile isolate ST8-SSI-h139-18
            SAMN40601845-rid21577343.denovo.020, whole genome shotgun sequence.
ACCESSION   DAYAOO010000020 DAYAOO010000000
VERSION     DAYAOO010000020.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN40601845
            Sequence Read Archive: SRR28438827
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 50902)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 50902)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-MAY-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-MAY-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002157583.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002157583.1
            Genome Coverage       :: 163x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/11/2024 16:19:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 4,038
            CDSs (total)                      :: 3,963
            Genes (coding)                    :: 3,930
            CDSs (with protein)               :: 3,930
            Genes (RNA)                       :: 75
            rRNAs                             :: 6, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 60
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 33
            CDSs (without protein)            :: 33
            Pseudo Genes (ambiguous residues) :: 0 of 33
            Pseudo Genes (frameshifted)       :: 7 of 33
            Pseudo Genes (incomplete)         :: 25 of 33
            Pseudo Genes (internal stop)      :: 11 of 33
            Pseudo Genes (multiple problems)  :: 8 of 33
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..50902
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN40601845-rid21577343.denovo.020"
                     /isolate="ST8-SSI-h139-18"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Denmark"
                     /collection_date="2018"
                     /collected_by="Statens Serum Institute"
     gene            82..1629
                     /locus_tag="ACGI5H_001308"
     CDS             82..1629
                     /locus_tag="ACGI5H_001308"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009906093.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative bifunctional diguanylate
                     cyclase/phosphodiesterase"
                     /protein_id="HFG9697019.1"
                     /translation="MNKNSMTRIYSLNKIIFIIIGILGIVLLTRHIEVDIKVLILILL
                     TLFSINVFISYLKIKLYEDKINLGLINNSDKFINITKDENFLKHVQNYIISNEKENCV
                     MACFDLCRLKLINDIYGYELGDEVLNNILSNLKNYFGKEAIYGKLKSDVFVLIIKLEN
                     REQKIPYLVNLIKNKIVILSQIDSFKMDINIEASIGIYKFNNNEIDIKKAIDNADMAR
                     LKSKGLKHIEYVEFDNAMEEEIQSIMKIERDLFLAIKNKEFVIHYQPKVDSSTGNIIG
                     SEALIRWLHPSLGMVGPNKFIPIAEKNGLINNIGRWLIQEVFITINKWISEGINVLPV
                     SINLSRVELYKNDLVDFFKLMFNTYNIPKELIELEITETTALRDVKFISERLYEIKSL
                     GMNISLDDFGVGNSNFINLKGIPLDIIKIDRSLILDIVTNTKTKFMVKAIVNLSHDLN
                     VTVICEGVEDMHQVKVLSELGCNFIQGYVFFKPLDEMNYKKLLTDGSYINLKDTLLDK
                     CMTVEEE"
     gene            1632..2030
                     /locus_tag="ACGI5H_001309"
     CDS             1632..2030
                     /locus_tag="ACGI5H_001309"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426473.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Rrf2 family transcriptional regulator"
                     /protein_id="HFG9697020.1"
                     /translation="MISEDVDYSIRIIRAIFNNGEDKPIDAKMILKSEDIPILTLYRL
                     LRKLCANNILTFNKEDGKTYMLNVSLDTISLRTIVEVIDGKIYINKCTRYVSNCSNCL
                     KGCKVNRELLEIEKEIYKLLSRKSIRQILE"
     gene            2070..3803
                     /locus_tag="ACGI5H_001310"
     CDS             2070..3803
                     /locus_tag="ACGI5H_001310"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422891.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0008170 - N-methyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="N-6 DNA methylase"
                     /protein_id="HFG9697021.1"
                     /translation="MDDISQDNFLLSKEYENSLDVDTKKASGIYYTPKIIVDYIVKKT
                     LKNHDIIKNPYPRILDISCGCGNFLLEVYDILYDLFEENIYELKKKYDENYWTVDNIH
                     RHILNYCIYGADIDEKAISILKDSLTNKKVVNDLDESDIKINLFCCDSLKKKWRYKFD
                     YIVGNPPYIGHKKLEKKYKKFLLEKYSEVYKDKADLYFCFYKKIIDILKQGGIGSVIT
                     PRYFLESLSGKDLREYIKSNVNVQEIVDFLGANIFKNIGVSSCILTFDKKKTKETYID
                     VFKIKNEDICINKFETLEELLKSSKFEHFNINQRLLSDEWILVNKDDETFYNKIQEKC
                     KYSLEDIAISFQGIITGCDKAFILSKDDVKLNLVDDKFLKCWIKSKNINKYIVDKSEY
                     RLIYSNDIDNENTNKRILDEIIGLYKTKLENRRECKSGIRKWYELQWGREKLFFERKK
                     IMYPYKSNENRFAIDYDNNFSSADVYSFFIKEEYLDKFSYEYLVGILNSSVYDKYFKI
                     TAKKMSKNIYDYYPNKVMKIRIFRDNNYEEIENLSKQIISILLNKSIDKGKVEKLQIK
                     MDNLIMDSLGI"
     gene            4035..5246
                     /locus_tag="ACGI5H_001311"
     CDS             4035..5246
                     /locus_tag="ACGI5H_001311"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422893.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="patatin-like phospholipase family protein"
                     /protein_id="HFG9697022.1"
                     /translation="MKGLVLEGGGTKGAYQIGAYKALRELGIEFQGVTGTSIGALNGA
                     YIVQNDIEVMEDIWLNYDYTHFMNIDRETYERFKNVDFTTKNLNAVFELINKARKNEG
                     IDISPLRQLMETTLNEDIIRKSKKDFGLVTVWWDKKINPYPLYIEDIPKGRLIDYLIA
                     SSSLPIFQTNMMDDKLYLDGMFCDNMPIGLLEDKGYEDVVVIRLIDDFIGKMNLNRHQ
                     NINIKTIIPSEYLGGSLNKDRDNVEKNIRLGYLDTMKAYERCTGIKYYFDVEYKYNEE
                     YCFDKFRSMSNETIQYICNLLNIKRDASLRTVMESVIPKLGEVLGLPKDFSYKDLFYC
                     IYEKKLEENNINRIKLYDFNKVIDVVNTNIDSNRNLASNFEVRPKISIKKNKNTKLLT
                     NCIIKDIKNQS"
     gene            5439..5699
                     /locus_tag="ACGI5H_001312"
     CDS             5439..5699
                     /locus_tag="ACGI5H_001312"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422895.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HPr family phosphocarrier protein"
                     /protein_id="HFG9697023.1"
                     /translation="MEKVVSIKNASGLHARPAGMFVKKAAEFKSTVEVVAKDKTVNAK
                     SIMGIMSLGLAQGEELKLVVNGEDEEVALAAMVELVESGFGE"
     gene            6053..7765
                     /gene="ptsP"
                     /locus_tag="ACGI5H_001313"
     CDS             6053..7765
                     /gene="ptsP"
                     /locus_tag="ACGI5H_001313"
                     /EC_number="2.7.3.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003431795.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008965 - phosphoenolpyruvate-protein
                     phosphotransferase activity [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoenolpyruvate--protein phosphotransferase"
                     /protein_id="HFG9697024.1"
                     /translation="MAYKGIGASPGVALGKALVVEHSELVIEKKSIDNVEAEIAKLED
                     AVAVSKEELVKVKEKASEELGAEEAEIFEAHLLVLEDPELIGSAIDKIKTESVNAEYA
                     LNEIKEMFVSMFESMDNEYMKERAADIKDVTNRILRHILGIKVVDLSALSEEVVLIAH
                     DLTPSDTATMNKKMVLGFLTDIGGRTSHTAIMSRTLEIAAIVGLNDITSKVKDGDFVV
                     FNGDTGEVIVNPDEETINKYTELKAKYEDERKALQLLKGKPSVTLDGKHVELAGNIGT
                     PNDIEGLIKNDAEGVGLYRTEFLYMDRDSFPTEEIQYEAYKAVLEGMDGKPIVIRTLD
                     IGGDKELSYLSMEPEMNPFLGYRAIRLCLDRKDIFKTQLRALYRASVHGRLRIMFPMI
                     SSLEELLQAKEVVKEVLAELDSEGVAYAKDVEIGMMIEVPSAAVISDVLAKHVDFFSI
                     GTNDLIQYTCAVDRMNQKISYLYNQFNPAVLRLIKTVIDNAHKEGKWAGMCGESAGDQ
                     KMIPILLGMGLDEFSMSPISILPARKLITSVKESDMKKLADDVLNMGTAEEIKSYIEK
                     TFNI"
     gene            complement(8557..9222)
                     /locus_tag="ACGI5H_001314"
     CDS             complement(8557..9222)
                     /locus_tag="ACGI5H_001314"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454127.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9697025.1"
                     /translation="MKGNIVQYNFADIEEEVYSLDYAIAWNTDEENVNIIPFTNKFCK
                     ESIESFCLGKINNFVEILNEGFVENHHYVHLDKMISVPKKKVNLVYQQDTHGYLLRDD
                     NDNLIPAKITSEQSKSISSKMELFCAGEEKCLINILLKADPSYILDVDSIKDKNILNL
                     GYESIDRYKEYNFDDDKILIFFINKKRYSVIMKKTNNSDNDLVSRNNAIKELFTNKAG
                     NLN"
     gene            9566..10996
                     /locus_tag="ACGI5H_001315"
     CDS             9566..10996
                     /locus_tag="ACGI5H_001315"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422900.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4116 domain-containing protein"
                     /protein_id="HFG9697026.1"
                     /translation="MDIKNKIKSIFLPEKNDYLDDEEFEYDIENNEEDLKEDNKVHLN
                     DLSRVKYDYRELKDIENQTEEMCLLAVKQDGTIIEFVKDKTYKVCMEAVKQTYKSLKY
                     ITNQNEDICIEAVKQNYRALYYINNKTENVLIEAIKNASTYDVMEVFKFVEEQTEDVC
                     LAFIERASKNDVAEILKGIKEQTPAICLEAVKKDGKSLAYVKEQSNSICLEAVKENYS
                     ALSCVKEQTEEICIEAVKQNDFALYYVNEQTEKICMEAVKRSYMALQYVNKQTEEICL
                     EAVRIDGRALQYVKEQTEEICLESVRQNGKVLQYVKKQTENICIEAVRGSFEELEIKE
                     ILSYVKIPTERIFVEAVKQNGKILKYVENQTELICLEAVRENYNALAYVKEQTEKICL
                     EAVNQSYEALKYVKEQTEEVCLKAVKQDYRMLKYVNNQTEKICLEAVKQNYRALEFVD
                     NQTEKVCLEAVKQNRKALQYVKQKQS"
     gene            11364..11942
                     /locus_tag="ACGI5H_001316"
     CDS             11364..11942
                     /locus_tag="ACGI5H_001316"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454130.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="accessory gene regulator ArgB-like protein"
                     /protein_id="HFG9697027.1"
                     /translation="MFKRYAEKMTSVLICNNMIDNNESKVYSYGFEILIAFIVNITTM
                     LFIGFLFGKFTYVLFFLMCYCPIRQFSGGYHADNYFRCLLTFIFIILSTILIIENINI
                     DLFKNIIMIIASVSWVGICVLCPIEHRSNPISDREKLVYKKTAIFISTVVLLITISSL
                     SLSIFVDYFTYSAFAMFWIFVMLVLGKLKAKV"
     gene            11972..12118
                     /locus_tag="ACGI5H_001317"
     CDS             11972..12118
                     /locus_tag="ACGI5H_001317"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426457.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cyclic lactone autoinducer peptide"
                     /protein_id="HFG9697028.1"
                     /translation="MKKFIVRFMKFASSLALSTAILSANSTCPWIIHQPKVPKEISNL
                     KKTN"
     gene            12414..13793
                     /gene="scfB"
                     /locus_tag="ACGI5H_001318"
     CDS             12414..13793
                     /gene="scfB"
                     /locus_tag="ACGI5H_001318"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728914.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0051539 - 4 iron, 4 sulfur cluster binding
                     [Evidence IEA];
                     GO_function: GO:1904047 - S-adenosyl-L-methionine binding
                     [Evidence IEA];
                     GO_process: GO:0031179 - peptide modification [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="thioether cross-link-forming SCIFF peptide
                     maturase"
                     /protein_id="HFG9697029.1"
                     /translation="MSMIHKFSMNGYNIVLDVNGGAVHVLDDVAYDLLDFYKEKSKEE
                     ILEILKSKYQEEKINEAYEEILNLEKEGLLYTEDTYQYHPSFVHREPVVKALCLNVAH
                     DCNLKCKYCFAAQGDFGGEKELMSFEVGKAAIDYLIANSGSRKNLEIDFFGGEPLMNF
                     EVVKQLVDYGRSVEKDYNKNIRFTITTNGVLLNDEIIDYINENMHNVVLSLDGRKEVN
                     DNMRPTLNDKGSYDITLPRFKKLVEKRAKDKYYYIRGTFTRDNLDFSKDVMHFADLGF
                     KLTSVEPVVGDESNPYALREEDLPKIFEEYEKFAVEYADRQLQGDGFKFFHFMIDLNQ
                     GPCVIKRITGCGAGNEYLSVTPNGDIYPCHQFVGNEEFKMANIFDEEIVLPENLKNMF
                     REAHVYTKEECKQCWNKFYCSGGCHANAINFNNDISKPYELGCEMQRKRTECSIMIQA
                     KLMLEGATN"
     gene            13822..14319
                     /locus_tag="ACGI5H_001319"
     CDS             13822..14319
                     /locus_tag="ACGI5H_001319"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422909.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gamma carbonic anhydrase family protein"
                     /protein_id="HFG9697030.1"
                     /translation="MIRDYLEDKPLIDESVFVAKSADVIGNVKIGKDSSIWYNAVVRG
                     DEGPITIGENTNIQDCSIVHGDTETIIGNNVTVGHRSIVHGCKISDNVLIGMGSIILD
                     NAEIGEYTLIGAGTLITSNKKFPPGVLIMGSPGKVVRELTEEDKKYIDESYEWYLEAA
                     QNQKY"
     gene            14617..16281
                     /locus_tag="ACGI5H_001320"
     CDS             14617..16281
                     /locus_tag="ACGI5H_001320"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891005.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC1 kinase family protein"
                     /protein_id="HFG9697031.1"
                     /translation="MRISYRNLKRYREIGYVLIKYGFSFIVERLNIEGIAYKIPLFDP
                     PEEIKNMTTGERMKRVLEELGPTYIKIGQILSTRKDLLDQDIIDEISKLRDDVEKFDS
                     NIAIDIFKEEVGLSIEEIFLEFKEEAIAAASIGQVYEGVLKTGEEVIVKIQRPNIEKI
                     IKSDLEILRTIANTLKDLKKDFNLDLVQMIEEFQTQLMRELDYTFEAINATKFSRIFK
                     NSDEVYIPKVYSEYNTKKILVMEKVNGTKLSDVEKIRRLGYNTKTIVEIGVRSFFTQV
                     LSHGFFHADPHPGNIFVVAKNKIAYIDFGMIGIIDNKTLNQLNEIALAGVEKNVDKII
                     YLLIEMDALNGEADIKGLRQDLLYLIHYYYDISIEKINVTDILNELFRFFRQYKIVMP
                     AQFVTLAKTVITLEGTSRTLNTDFSFGSMGKEFMKHHYKSKFNPKNVVLSSRQNVEEI
                     LLDIKTIPKQLKAILKNIERNNIKMQIEDVKMTRLENCIIELTSQISLSLVLASIIVG
                     SSLIIASPNIENNIWIKFTAIAGFFISFIIGLCLVIRSIRSKYKKD"
     gene            16294..18744
                     /gene="recJ"
                     /locus_tag="ACGI5H_001321"
     CDS             16294..18744
                     /gene="recJ"
                     /locus_tag="ACGI5H_001321"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422914.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008409 - 5'-3' exonuclease activity
                     [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded-DNA-specific exonuclease RecJ"
                     /protein_id="HFG9697032.1"
                     /translation="MKKWILKYKGKIEESEFSKKLNISPEICQILKNRGICTEKDSEI
                     FMNPSLDYLRDPFLMKDMQKAVDRIKLAVEKNEKIWIYGDYDVDGVSSTSILCLYFKS
                     IGYNVDYYIPNRLEEGYGINEDAIKLISSRGCDLIISVDCGITSVSEVNTANDLGIDV
                     IITDHHECQSEIPSAFAVINPKQEDCNYPFDSLCGCGVAFKMIQALTPKEEFKTSMYN
                     YLEIVTLATICDIVPLIDENRIIVKNGLKSMKEGKNIGLRELIKVCGVESDKIGSSHI
                     GFAIGPRINASGRLGYSYLGVELFTTQSQEEAVEIASILEEKNNERQMIEAKMYHEAE
                     EMLKSNSRYNDDKVLVLAKEGWQHGIIGIVASKLTEKYYKPTILLGIENGEATGSARS
                     IKGFNIFEALIKCKDLMTKFGGHEQAAGLSLDSDNVEILANEINKFADYNLTEDDMIE
                     NVNVEFELQENVINLNLVEELHKLEPFGLNNPNPRFIVRNYILKDLKVIGKNQQHLKL
                     SIEKEKSYECIGFNMSHLKSMYKVGDKVDVLFQLDENNYMGNRKVQFLLKDIRLARPK
                     SASNDKLSLKLMSKIIPKDTQSLYNISVSDFELFDGNTDINIFDYFEKDTLIISNSIN
                     GFYRAMSDISLIDLDFNINYNIIEDVSKNTDKLELIFSPNIDKIDLKRYNNIILYDYL
                     YNKGEYSYIYENKREESEIIKYYNKTDLLYLKNVVSNIVPSRDEFITIYKQALIKKEI
                     DLDMVNIRETFNVIPLKFFTILNVFRELNLLDFNLNYEKNSVLIRILPKPQKKLDLNE
                     SLILNNLKNLEKQYNSSY"
     gene            18757..19269
                     /locus_tag="ACGI5H_001322"
     CDS             18757..19269
                     /locus_tag="ACGI5H_001322"
                     /EC_number="2.4.2.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426450.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003999 - adenine
                     phosphoribosyltransferase activity [Evidence IEA];
                     GO_process: GO:0006168 - adenine salvage [Evidence IEA];
                     GO_process: GO:0009116 - nucleoside metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="adenine phosphoribosyltransferase"
                     /protein_id="HFG9697033.1"
                     /translation="MDLKNFIRNIDDFPKPGIDFKDVTTLFKDGDAFKYAVDSIVEEL
                     KDKDVDLVIGPEARGFLMGTPVAYALGVGFVPIRKPGKLPGEVESYEYGLEYGTDTLE
                     IHKDAIKKGQKVAIVDDLLATGGTMEAAAKLVEKLGGEVVSMQFLIELKFLNGREKLS
                     NYDVNSLIKY"
     gene            19343..21550
                     /locus_tag="ACGI5H_001323"
     CDS             19343..21550
                     /locus_tag="ACGI5H_001323"
                     /EC_number="2.7.6.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422921.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0015970 - guanosine tetraphosphate
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional (p)ppGpp
                     synthetase/guanosine-3',5'-bis(diphosphate)
                     3'-pyrophosphohydrolase"
                     /protein_id="HFG9697034.1"
                     /translation="MHDKELQEIIEKIKVYAPNANFEMVEKAYNLAKKAHEGQYRKSG
                     EPYFIHPLAVANILIEMELDIETITAGLLHDVVEDTEYTYEDIKKEFGKEVADLVDGV
                     TKLGQIKYRSKEETQSENLRKMFLAMAKDIRVILIKLADRLHNMRTLKYMPPEKAKYK
                     AKETLEIYGGIAHRLGISKIKWELEDRALRFMDPEGYYDLVSRVSMKRSQREDYIQGI
                     VELLKDKFKDLSIPCDVYGRPKHFYSIYRKMQKKHKTFEEIFDLTAVRILVDNVKDCY
                     AVLGIVHTLWRPIPGRFKDYIAMPKPNMYQSLHTTVVGPDGEPLEIQIRTHEMHNIAE
                     NGIAAHWKYKEGISSKESKVEEKLQWLRQMMEWEKDLKDPQEFMDALKEDVFNSQVYV
                     FTPKGDVIELPAESTPIDFAYRVHTNVGNKCVGAKIDGRIVPIDYKLQNGNIVEVLTS
                     SNSNGPSRDWLNIVKTPNAKSRIRQFFKKERREENVDRGNTILEREFKKHDIPQKDPL
                     VEKYMALVAKKFNQPSVEDLIATVGYGGIMSSQVVSKVKDLYLKEVKKAKKEQQIQEE
                     DLNKHNISETEYSKKRKKNASQGIIVKGLDNILVRFAKCCNPLPGDEIVGYITKGRGV
                     AIHRADCPNANNNGDFFQNRLVEVSWSSAGKGKFEAEIQIKAIDRRGIVNEITHIVAM
                     DKLSLNGINARKGKDSIVSINLLVEVNDTEELKILMKKLKAIPGVESIYRMTN"
     gene            21575..22024
                     /gene="dtd"
                     /locus_tag="ACGI5H_001324"
     CDS             21575..22024
                     /gene="dtd"
                     /locus_tag="ACGI5H_001324"
                     /EC_number="3.1.1.96"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426448.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004045 - aminoacyl-tRNA hydrolase
                     activity [Evidence IEA];
                     GO_process: GO:0008152 - metabolic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="D-aminoacyl-tRNA deacylase"
                     /protein_id="HFG9697035.1"
                     /translation="MRAVVQRVSSSKVTVDENTIGQINKGLLVLLGVTHDDKSSDVDY
                     MIDKILNLRIFEDENDKMNLSLMDIGGELLVVSQFTLYGDCRKGRRPGFSNAARPELA
                     NNLYEEFVKKAKDKGVTVGTGQFAAHMMVELTNDGPVTILLDSSKSF"
     gene            22039..22653
                     /locus_tag="ACGI5H_001325"
     CDS             22039..22653
                     /locus_tag="ACGI5H_001325"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891001.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HFG9697036.1"
                     /translation="MIIKKFVDSYFGVNTYVLGDEKTKKCAVIDPGGSLVETLSFVKE
                     NELNIEYIILTHGHGDHIGYVKDIKEKTGAKVVAHVDEKELLNDKNKNLSYTMRCGAQ
                     EFDADIYVNDKDKLELGELKMTFLHTPGHTQGCMCIRVEDEMFTGDTLFAGSIGRTDL
                     YSGDFNQMEKSLKKLCKYEDAVRVYPGHGPTSTLGVEKKTNPYM"
     gene            22744..24300
                     /locus_tag="ACGI5H_001326"
     CDS             22744..24300
                     /locus_tag="ACGI5H_001326"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422926.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="coproporphyrinogen III oxidase"
                     /protein_id="HFG9697037.1"
                     /translation="MLYVFLKGHDYKYEVAELIKLFTSEFKFKDSNANNNIESKHLIN
                     RLIYENGVLFSSTEYYENGNLKYESIQNIENMNLEFLDGFDSSKTIEEFLNSLDSESK
                     RNFKKLCKENIKKSMFLVLKQVFNSYVPWGILTGIRPVKIVHNLMDKKLDDNSIRTIL
                     KDNYFIIDEKIDLALEIAKRERLFMYPIDKNKISLYVSIPFCPTRCVYCSFPSNSLKQ
                     FGHLKREYVYKLIEEIKGFAKVIKDTKKEVETLYIGGGTPTTLDEEELDLLINSLFNE
                     LDLSKIKEFTVEAGRPDTITEQKLRVLKKHNVSRISINPQTMNDDTLVKIGREHRVSD
                     LVDCFNMARRMGFDNINMDIILGLIDEDLNMVKNTLEEIKKLSPESLTVHTLAIKRAS
                     NLNINMDRYKEHLTQYEEMVKMIDLSMKYAKDMGLNPYYMYRQKHMLGNLENIGYAKE
                     GYECIYNIQIMEEKQSNYALGAGAISKFVYVDEDRIERVENVKNVEQYIERVDEMIKR
                     KKEEVYKNVD"
     gene            24290..25552
                     /gene="hisS"
                     /locus_tag="ACGI5H_001327"
     CDS             24290..25552
                     /gene="hisS"
                     /locus_tag="ACGI5H_001327"
                     /EC_number="6.1.1.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422928.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0004821 - histidine-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006427 - histidyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="histidine--tRNA ligase"
                     /protein_id="HFG9697038.1"
                     /translation="MLTKAPRGTKDITPKEAYKWRYVENKFREICALYGYEEMVTPIF
                     EHTELFKRSVGDTTDIVQKEMYSFKDKGDREITLKPEGTAGVVRAFIENKLYADTQPT
                     KLFYVTPCFRYERPQAGRQRQFHQFGIEALGSDTPSMDAEIIALAVQFFNEVGLNDLV
                     VSINSVGCPVCRKEYNALLKEYLDSKADILCDTCNERREKNPMRVIDCKNPTCKENIK
                     DIPFIADHLCDDCKSHFDKLQEYLKEMNINFVIDKTIVRGLDYYRKTAFEIISNDIGA
                     QSTVCGGGRYDGLVEQLGGPKGISGIGFGLGIERLLLTLEGNGIEIENPQSTDIFIVT
                     IGEEANTRSFKLLKDLRQNHISADKDHIERSVKAQFKYSDKINSKFTIVIGDDELKND
                     TATLKNMKTSEQTTVKLSTLVEELKQKL"
     gene            25626..27413
                     /gene="aspS"
                     /locus_tag="ACGI5H_001328"
     CDS             25626..27413
                     /gene="aspS"
                     /locus_tag="ACGI5H_001328"
                     /EC_number="6.1.1.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454140.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0004812 - aminoacyl-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016874 - ligase activity [Evidence IEA];
                     GO_process: GO:0006418 - tRNA aminoacylation for protein
                     translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate--tRNA ligase"
                     /protein_id="HFG9697039.1"
                     /translation="METLKGLKRTHYCGELREKNINEEVVLMGWVQKKRNLGGLVFVD
                     LRDTSGLCQIVFDTDVDKEAFEKAEKLGAEFVIAVKGKVCERQSKNPNMPTGDIEIFA
                     TELRLLNKSETPPIYIKDDDDVSEALRLKYRYLDLRKPSMQRNLKLRHKVMNITRNYL
                     SNNRFCEIETPFLIAPTPEGARDYLVPSRVNPGKFYALPQSPQLYKQLLMVSGMDRYF
                     QIVKCFRDEDLRADRQPEFTQIDCEMSFVEQEDVMSMIEGLLEAIFKEVLDVELALPL
                     PKMTYAEAMSKYGSDKPDTRFGYELTDISDVVCNCGFKVFADATQPGKSVRGINVKGK
                     ADDFTRKQISSLEEHAKTYRAKGLAWMKVGQEGVTSPIAKFFNEEEMNAILTRMNAEV
                     GDLLLFVADKNSIVFDALGQVRLEVANRLNLLDKNVYNLLWVTEFPVFEEDEETGTFS
                     AMHHPFTSPMDEDLDKLEEGDKSSLRAKAYDIVLNGYEIGGGSVRISNSDVQSRMFKA
                     LGFTEERANEKFGYLLEAFKYGTPPHAGLAFGLDRLVMLLAGTDNIREVIAFPKNQNA
                     VCPMTNAPTLAEDEQLEELSIKVDIKDNE"
     gene            27872..29104
                     /locus_tag="ACGI5H_001329"
     CDS             27872..29104
                     /locus_tag="ACGI5H_001329"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728912.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytosine permease"
                     /protein_id="HFG9697040.1"
                     /translation="MQEREELVLNPVPKEERVGWLAPLFNMLGSNIAISELMVGGTLI
                     LGMTLSNMIITSIIGNLILVAIIMIQGYIGYKEGLNTYVLAKGAFGEIGGKYLISLLL
                     GITSFGWFGVQAGVAGLSVQKIFPSVNLTLVTVILGLFMVVFALYGFKAMAKFNYLVI
                     PPLMILMVWGVFKAFSTYGVEAIYNYTPQTTMSMVEGLNIVVGLVIVGAIISPDQLRY
                     TRRVKDIWIISFLGLGIISLFQQVAAGVMSMGAPTWDITEVLANLGFGWVAFVILILA
                     SWSTNVSNAYSGGLALKTIFPNVKRNVLTLVAGLIGTIIAATGIIFKFQSFLSFLGIA
                     VPAIAGIMWCEYYFIQGRTYKHREGINWIAVISWLIGFAASYYSSKINFLIPPINGIV
                     VSMVIYYILMNCFGIKDK"
     gene            29118..29924
                     /locus_tag="ACGI5H_001330"
     CDS             29118..29924
                     /locus_tag="ACGI5H_001330"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890994.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0008152 - metabolic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="nitrilase-related carbon-nitrogen hydrolase"
                     /protein_id="HFG9697041.1"
                     /translation="MGRKVKIGIIQQHSVLGNVKKNIEKAVEMIDDLGKQGADIICLP
                     ELFATGYNLESLGGVKTLELIREHNKYIEESMSEAAKRNNVYLISPYGTLEKGSTHVY
                     NSAVIFDRKGKIMGEYCKNHLWSLEAVYFKGGEKVEVYDADFGRFGVMICYDAGFPEV
                     SRELTLKGSEIIFIPSAWRIQDEDMWDLNVSQRALENTVYTVGVNLVSNDSNLILFGK
                     SKICNPRGTVITQLDTYREKYVLSEIDLDEIKKYREDIPYLKDRKSSYNI"
     gene            complement(30036..30905)
                     /locus_tag="ACGI5H_001331"
     CDS             complement(30036..30905)
                     /locus_tag="ACGI5H_001331"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454143.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HFG9697042.1"
                     /translation="MDLLHLKYFQTVARMEHITKASHKLNIAQPALSKTISSLEKELG
                     VQLFDRKGRYIVLNEYGRLFLKRVDSILDLVESSKKELQDTSLENSGEVKILSPAAAN
                     VLPSLLSNFRKLYPNITFNVSHTLPSSYKKSDFDLYISSSFTKLNSENSITLTCEEIL
                     LGVSINHPLSLKDEVYLSEVSDENFIVITKGENYREVIDILCESANFKPKIAFESDSP
                     YTIYALIKSLQGVGFICGKSWGLSQDPEIKLLHIKDIEFKRYLNLSWFSENYESKAVL
                     LFKNFLINYFKNI"
     gene            31277..32704
                     /locus_tag="ACGI5H_001332"
     CDS             31277..32704
                     /locus_tag="ACGI5H_001332"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903316.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall-binding protein Cwp14"
                     /protein_id="HFG9697043.1"
                     /translation="MKLTKSISSMLCLSLVLSLSPVAYANEISRTTVENTLVGQDRYQ
                     TAVEVSKKGWSSANEAVVVNSESIVDALAVTPFAKLKNAPILLTEKNNLNSQTEKELK
                     RLGVKKVYIIGLSSSVSNDVQKQLESNNLTTDRVGGSDRYQTALSIAKKIEGLKDISE
                     IAVVNGYTGLADAVSIASVAATNGMVILPVSDASGISSFKDFIESKNINKSYIIGSTN
                     AVSDKIKQSLPNSERIGGADRNETNGKVIEKFYTSNKLNNVFVAKDGMKNQNQLIDAL
                     AVGVLASKENSPVLIVGEQLSATQKSVFSNKNATSITQVGSGGNENAFKELKDLQANS
                     NNKRVMYVTNTDKVNIRNDATIEASVIGYLNNGDEVEVLDVLKTGWVEIKYNEGIGYV
                     SGSYLTNNKPDNSNENIKIKYVKEKDGLNVRKGPSTEDEKIGHLSYGSKVETIEMFAT
                     GWVKIKYNGGYGYVSNDYLSDTPVI"
     gene            complement(32781..33050)
                     /locus_tag="ACGI5H_001333"
     CDS             complement(32781..33050)
                     /locus_tag="ACGI5H_001333"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903315.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9697044.1"
                     /translation="MKFEYYYLIQDIAGILLAFIGLRMSIIGFRILSMKGLSINTLLI
                     VIKYCLFTIAGLNLLISKFGIRHWIWSVCMLIISIIINPRIKVSK"
     gene            complement(33053..34495)
                     /gene="nhaC"
                     /locus_tag="ACGI5H_001334"
     CDS             complement(33053..34495)
                     /gene="nhaC"
                     /locus_tag="ACGI5H_001334"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897909.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0015297 - antiporter activity [Evidence
                     IEA];
                     GO_function: GO:0015385 - sodium:proton antiporter
                     activity [Evidence IEA];
                     GO_process: GO:0006814 - sodium ion transport [Evidence
                     IEA];
                     GO_process: GO:1902600 - proton transmembrane transport
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Na+/H+ antiporter NhaC"
                     /protein_id="HFG9697045.1"
                     /translation="MKMNTERKIPSFRYSLLVMLAIIALTSVGIVVFNASITTMFLLS
                     WLIVVPAAMKLGYTNDEIEAFGFEVGKDAFQSNLIILSVGVLIAAWIAAGTIPTVVYS
                     GLTIITPKYFLLTTLIVCSLTSVATGTSWGTLGTSGIAMMSIGTSMGIPLGLTAGAVI
                     SGAFFGDKMSPLSDSTNLAAAVCKTDVITHMKHMFYTTGPAYVICIVLYTVIGFKYSN
                     NTIDYVQINQIKDVLNSNFHIGLVAMIPIIFLLLLLLLQKPPIISILSSAIMGLIIAV
                     FQEGEKIGDVLNYMLSGFTIDTGFVYADKLLNRGGIMSMAETVLLVFVVFVIAGILQK
                     TGFLEVLLQPLITKIGKSRTKLVGSTFIVSYFANAFSSSMMFTSVFVGTLMSPIYKEF
                     KLKPQNLSRIIEDTATLGGPLIPWNSNAVFCAQTLGVSPLEFIPYCFLSWITPIISFI
                     YGVTGFTMLTYTDDEIEELEIFDTAQRRVD"
     gene            complement(34520..35686)
                     /locus_tag="ACGI5H_001335"
     CDS             complement(34520..35686)
                     /locus_tag="ACGI5H_001335"
                     /EC_number="4.4.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897908.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA];
                     GO_function: GO:0047804 - cysteine-S-conjugate beta-lyase
                     activity [Evidence IEA];
                     GO_process: GO:0009086 - methionine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MalY/PatB family protein"
                     /protein_id="HFG9697046.1"
                     /translation="MNYNFNEIVDRSNNFSSKWSEMEKKYGTNDLLPMWVADMDFKAA
                     PCIIDSLKNRLEQEIYGYTTRPDSYNESIVNWLDRRHNWKIKSEWLIYSPGVIPAISL
                     LINELTKANDKIMIQEPVYSPFNSVVKNNNRELIISPLQKLENGNYIMDYEDIENKIK
                     DVKLFILCNPHNPVGRVWTKDELKKLGDICLKHNVKIISDEIHSDIILKKHKHIPMAS
                     ISKEFEKNTITCMAPTKTFNIAGLQSSYVILPDEKDYKLLDDAFTRIDIKRNNCFSLV
                     ATEASYNNGESWLESFLEYLESNIDFAIKYINENMPKLKVRKPEGTYLLWVDFSALGL
                     SDEELESILVQKGKVALNQGNSFGIGGSGYQRINLACPRSMLEEALIRIKNAIN"
     gene            complement(35911..38031)
                     /locus_tag="ACGI5H_001336"
     CDS             complement(35911..38031)
                     /locus_tag="ACGI5H_001336"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426412.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0008134 - transcription factor binding
                     [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sigma 54-interacting transcriptional regulator"
                     /protein_id="HFG9697047.1"
                     /translation="MKQMELAIVSLKKDAGEIYENQIRQFLGDNLKINLYSFEEGNLK
                     FFKEKLILLSAYLKYDEIVKLSHYDAQIIVPKLTFEKNSIDMISKLEKDKIIYVYNLS
                     KDMAIETISLIHRLGIDNINILPCYPEIEFTPTDAVILTPGEKILPKFKNCEVIDLKY
                     RIIDLSCIVEIATKTKLKHLIKDDLIKKYVEKIIPTSYSTGELLLDANKFERQFDLLL
                     SIIDDGIICTNNDGIIQFYNHMARKILSINANEMIDSFVGDCIKDINFQSILTNKTPF
                     FEKLIKINHIDINLEIKHIQLNVFDGFILKMTKFSQLEKKQAKLRAQLVNSGNISKYT
                     FDDILGSSIQTINTKKIANKMAQSNSSILIIGESGTGKELFAQSIHSASRRKDGPFVA
                     VNCSTFQENLLQSELFGYDEGAFTGAKKGGKIGLFELANNGTIFLDEIGEMDLNSQSK
                     LLRVIQEKQVRRIGSNNVIDIDVRIIAATNRNLKELVSKNMFRRDLYFRLNVLPLKIH
                     PLRERPADIFEIFGSLKYDIPCNFILSEEVKEIFKMYRWEGNVRELRNLGEYFCYLEK
                     DIIEICDLPEYILDTIDSNYSRTVCNKVSDNIKKYQFNIGKDKNIMKYDYNFKRSLDE
                     YIFILDNLKKAYDLKERIGRKSLCKIALEENRFLTEQQIRNMLLELQNFGLVDILVGR
                     GGSIITSKGVEFLKNINRSNKLNS"
     gene            38264..38665
                     /locus_tag="ACGI5H_001337"
     CDS             38264..38665
                     /locus_tag="ACGI5H_001337"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422946.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9697048.1"
                     /translation="MKKCLYCNRDIKSPNNKLAIKYDDNMNIYPCRAECKEKIEEYIA
                     KKPTYKFINILEVLLGVGGIFCFLSKWTIAAQVVLGIDALVIFLFPLAGFKMNGKLSM
                     EQTKNQSRSIAISILAFIVIITVLYFKQVGK"
     gene            38708..39001
                     /locus_tag="ACGI5H_001338"
     CDS             38708..39001
                     /locus_tag="ACGI5H_001338"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422948.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal-sensitive transcriptional regulator"
                     /protein_id="HFG9697049.1"
                     /translation="MEERKLAPNNEREALIKRLKRIEGQVKGIQKMVEQERYCVDILV
                     QISAIRSAINRVGTIILENHIKGCVAESIKHDDADKTEEMIKELMDTINKFTK"
     gene            39016..39456
                     /locus_tag="ACGI5H_001339"
     CDS             39016..39456
                     /locus_tag="ACGI5H_001339"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454154.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SoxR reducing system RseC family protein"
                     /protein_id="HFG9697050.1"
                     /translation="MNQQGFIMEIVDDRTAKLKMQRHSACAACGKCATTNSAESKEIL
                     VEVDNTIGAKVGDHVEVSMDNMNVLKAAVMAYIIPLIALLVGTIGTYYILGAIGMTTG
                     VEAISGLVGICLTIICYLYLKKNDKKFRDSREFIPVITRILIDL"
     gene            complement(39548..40021)
                     /locus_tag="ACGI5H_001340"
     CDS             complement(39548..40021)
                     /locus_tag="ACGI5H_001340"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454155.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonine/serine exporter family protein"
                     /protein_id="HFG9697051.1"
                     /translation="MTDMSMILHFLFSGVATAGFAVFFNAPLYLLLPAGVTGGIGWIV
                     YVYLFNFTTNAVFAGFIAAALVSACSETLARKLKQPAIVFVIPGILPLIPGIGLYNTM
                     LSLIQKNYSLAMSKGTDALFLSAAIALGVLVVTSFVRTLNLLKIRKNFIPYRKSK"
     gene            complement(40021..40809)
                     /locus_tag="ACGI5H_001341"
     CDS             complement(40021..40809)
                     /locus_tag="ACGI5H_001341"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422952.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonine/serine exporter family protein"
                     /protein_id="HFG9697052.1"
                     /translation="MNQNEELEYKKNILKLALFVGELMIKNGAETSRVEDSVLRICRS
                     RGFYHVNIFTTPTVIIISDEKFDGFSFMKTIQSRGINLNKISLLNSFSREFVSDKEYD
                     IDNAIARLYEIQDVKPYPLWLFYSCTGIASACFACLLGGNYVLNFILTFIIAIFAAIT
                     YDKTMKISAISAFSCLVSSFLIALSGVLLVEIGILDDPKMLIVGAIMPLLPGVAFIKA
                     IRDLISGNLISGISRAFDAAMIIIAIASGVGFVLDTWYRIGGPF"
     gene            41137..42381
                     /gene="glyA"
                     /locus_tag="ACGI5H_001342"
     CDS             41137..42381
                     /gene="glyA"
                     /locus_tag="ACGI5H_001342"
                     /EC_number="2.1.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422953.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004372 - glycine hydroxymethyltransferase
                     activity [Evidence IEA];
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA];
                     GO_function: GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA];
                     GO_function: GO:0070905 - serine binding [Evidence IEA];
                     GO_process: GO:0019264 - glycine biosynthetic process from
                     serine [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="serine hydroxymethyltransferase"
                     /protein_id="HFG9697053.1"
                     /translation="MFENLKKADPEIYESMKRELKRQQRNIELIASENIVSVPVMETM
                     GSHLTNKYAEGYSGKRYYGGCEYIDEVETLAIDRIKKIFGAEHANVQPHSGANANIGV
                     YFAMLKPGDVVMGMNLSQGGHLTHGAPVNISGQYYKFYEYGIDKDSGLIDFDEVRKIA
                     HEVKPKMIVAGASAYPREIDFKKFREIADEVGALLMVDMAHIAGLVAAGLHQNPCEVA
                     DFVTTTTHKTLRGPRGGVILCKEKYAKDIDKAIFPGIQGGPLEHIIASKAVCFKEALS
                     DEFKEYQVQVAKNAKALAEELIKRDFKLISGGTDNHLILLDLTNKNITGKAAEKRLDD
                     AYITANKNTIPFDPNGALITSGIRLGTPAVTTRGMKEEDMAIIAEAIDLCLTYDEESK
                     ARTLVVGLTEKYPLYEEYNIMD"
     gene            42704..43801
                     /locus_tag="ACGI5H_001343"
     CDS             42704..43801
                     /locus_tag="ACGI5H_001343"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422954.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016758 - hexosyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HFG9697054.1"
                     /translation="MKVLILTGKFGMGHYSASNSLSEDIKAKFDNSEIIIKDIFEYIM
                     PNYSDKMYKTFSILVNRGSSLYNLFYKCAENGKKDIKFTFSDYFLNKLDTLLHEVQPT
                     VVISTFPFCSQLVSRYKEKYNSNLPLITCITDISSHSEWISKNTDCYLVASKSTKEEL
                     VFKGIDESKIKVNGIPVKKEFKRIEHVNHSTKKNILIMGGGLGLLPKSEQFYKELNSL
                     EGVKTTVITGNNKKMYYKLYGRYENIEVVGYTNEVYKYMKDSDLIISKPGGITLFETI
                     YSELPILAFNPFLQQEIDNASFILNNEIGRILGKNKKYYVDEIKDLIYDDATLKEMSS
                     NMKELKKQFDNNTLENILFSLDEQGACRECM"
     gene            43792..44490
                     /locus_tag="ACGI5H_001344"
     CDS             43792..44490
                     /locus_tag="ACGI5H_001344"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422955.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide deacetylase family protein"
                     /protein_id="HFG9697055.1"
                     /translation="MYVVGLIIVVALIFLVHSIIPTYYNKLLNKEVLKNMAGENEIAL
                     TFDDGPDKRYTEKLLDVLKENDIQAMFFVVAKNAEKEPEIIKRMLRENHIVGLHSLEH
                     RNAWLYSYSYVKKDFIESTNIMKNLGVDVNYYRPPWGHTNIFSNSFVKKYNLKMTLWD
                     VMAEDWEKDSTVDIIINKLMSRTKENSIICLHDAGENSGGAVGAPERTIEALKIAIPK
                     LKASGLKFVTPERM"
     gene            44493..45557
                     /locus_tag="ACGI5H_001345"
     CDS             44493..45557
                     /locus_tag="ACGI5H_001345"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890975.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YbhN family protein"
                     /protein_id="HFG9697056.1"
                     /translation="MISKTEKKNKCLGSVAFLVLLMGITGYFVFRGQSVESLIKSLKG
                     ASPMFILIGFAMMFIYVACEGINIYLGMKALNQKTTLLKCMGYAFIGFYFSSITPSAS
                     GGQPAQVYYMKKDDINISYSSLILLVIVVIHQVVILAYSGIMFIMEREFILNNVSGMN
                     ILLIYGVITNVALVIGVIAIIFSKKLVNNFIISITNLLGKLRIIKDVESSRKVIISQI
                     EEYVKGAQYIKQNPKLVVQILVITIVQITAMFLVPFFVYKAFHLSTYTVFEILAIQSL
                     LNIAVSSLPLPGAVGASENSFMTLFKIFFPGHLLVPAMLLSRGISFYAFVAISGLICI
                     VVHVKSSEKVKAVKKVAYVR"
     gene            45740..46444
                     /locus_tag="ACGI5H_001346"
     CDS             45740..46444
                     /locus_tag="ACGI5H_001346"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426384.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000156 - phosphorelay response regulator
                     activity [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HFG9697057.1"
                     /translation="MNKEIPKKILVADDNPEIREIVEILLTGEGYEVIMATNGEEAVN
                     LVDSTIDLIILDVVMPVKTGFVACNEIREKTTAPILFLTAKTQDSDKVIGFSAGGDDY
                     LSKPFSYSELISRVKSLLRRYYIYQGKEKEREPNILKTKELCVNLDTQDVTLNGEPVF
                     LTTIEYSILILMLKNRKKVFSSENLYETIWDEQYFYTANNTIMVHIRNLRKKLEKDQK
                     NPQYIKTAWGKGYYID"
     gene            46437..47759
                     /locus_tag="ACGI5H_001347"
     CDS             46437..47759
                     /locus_tag="ACGI5H_001347"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454160.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000155 - phosphorelay sensor kinase
                     activity [Evidence IEA];
                     GO_process: GO:0007165 - signal transduction [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="histidine kinase dimerization/phospho-acceptor
                     domain-containing protein"
                     /protein_id="HFG9697058.1"
                     /translation="MINKIKPSKLGVILLIYVVISAAVAFILNIPFYSAVESIVKDVS
                     EGKVYFKREVNQLMDNFQTYVNNNGIRADDGDDIAKWNSDNWFVSMKIYKGNKVFYDT
                     LYYPNEVPDKSEENEFYSSPMARNYEIQFSDIKANIVVVALFRFRFQNFIEAISITFM
                     ALTFIITFLLLFSRKIKYLRKIEMGIKIVESGSLKYRIPVKGNDELSSLASSINEMSH
                     TLENQLIKEREMKNKNKDIVTSISHDVRTPLTSVICYLDLIKDHKYNSPEQLEQYIKN
                     VRSKAYQIKDLTDDLFTHFVNSGEEVSKGYEKINANEFIFQLLLDSSYTLEEKGFHIT
                     IENELYNQYHIYVDVTQFRRIFDNLCSNIIKYARKDKPIVFLIKVEDSKLLIIQKNRV
                     SNFSKNVESFGIGIKNCEKIVAYHNGSINVNSDDKEFAIEISIPAKES"
     gene            47946..49319
                     /locus_tag="ACGI5H_001348"
     CDS             47946..49319
                     /locus_tag="ACGI5H_001348"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890970.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9697059.1"
                     /translation="MVLTGAHYIYILFMVIILITMIMKKDTIVPCILGVFFMGLFFEK
                     NIFGAITAVFNSFIISLNELGPIILIIAIMVALSKALEANNAIQYMVRPFSRVIKNSN
                     TAFFVTGFVMLVLSWFFWPTPAVALVGAVFLPVAMRAGLPAIGVAVALNLFGHGLALS
                     TDFVIQGAPSITAGAAGVAVSYVINDGMILFWVMGIVTISMAFYTLKRDINKGMFREE
                     LKGFESEEVEEFNGKSKIATILVALGFLADIIAMYIFDLKGGDASALLGGTAVFLIII
                     INVINFGKDSLENVCENIIDGFVFGIKIFGAIIPIAAFFYMGEVAPLTGVFGKVLAPG
                     SQGLLSDIGIALSQTIPLNKFAVSGIETVVGAITGLDGSGFSGISLVGSLASVFGTAI
                     NASVGALAALGQISGIWVGGGCLVPWGLISAAAICGVSPIELAKRNFVPVITGLVVTT
                     IVAMFII"
     gene            complement(49691..50629)
                     /gene="pdaA"
                     /locus_tag="ACGI5H_001349"
     CDS             complement(49691..50629)
                     /gene="pdaA"
                     /locus_tag="ACGI5H_001349"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897898.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016810 - hydrolase activity, acting on
                     carbon-nitrogen (but not peptide) bonds [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="delta-lactam-biosynthetic de-N-acetylase"
                     /protein_id="HFG9697060.1"
                     /translation="MFRKVLHYLTLLSISIFFIVGCSNSQNNQNENQNKETQLQEDKE
                     KIDSGKDTSNVIVSDGTDKPSKATTNNDNNKLDVSSLDNTTLDWFYIPNNKHKTPEVN
                     TDIEFKFSDYDALYNGPTKDGQKTLYLTFDEGYENGYTTKILDTLKQNQVKAVFFVTA
                     PYIKENKDLVKRMVSEGHIVGNHSKTHPSMPTKTSNLKNFNDELYDVEKLYKDVTGKD
                     MVKFFRPPMGKYSEKSLAMTKNLGYKTVFWSFAYRDWDTDKQPSHEEATQKIMDNLHD
                     GSILLLHAVSKTSTEILNDFISNARKLGYEFELLEY"
BASE COUNT        19842 a         5578 c         8619 g        16863 t
ORIGIN      
        1 ttgatttgct atcaattgtg ctttataatt agtatatata aagtttaact gtaagataat
       61 ttaaaaaata ggggaattta tatgaataaa aatagcatga caagaattta cagtttaaat
      121 aaaataattt ttattataat tggaatttta ggaatagttt tactcacaag acatattgag
      181 gtagatatta aagttttaat tttaatttta ttaaccttgt ttagtataaa tgtatttatt
      241 tcatatctta aaattaagtt gtatgaggat aaaattaatt taggattgat aaataattca
      301 gataagttta taaatattac taaagatgag aacttcctaa aacatgttca aaattatatt
      361 atcagtaatg aaaaagaaaa ctgtgtaatg gcttgttttg atttatgtag actcaaactt
      421 ataaatgata tatatggtta tgagctaggg gatgaagtgt taaataatat tttaagtaac
      481 ttaaaaaatt attttggaaa agaagctatt tatggaaagt taaaaagtga tgtttttgta
      541 ttaataataa agcttgaaaa tagggaacag aagattcctt atttagtaaa tcttattaag
      601 aataaaattg tgatactaag tcagattgac agttttaaaa tggatataaa tattgaggct
      661 tctattggaa tttataaatt taacaataat gaaattgata taaaaaaagc tatagataat
      721 gctgatatgg caagacttaa atcaaaagga ctaaagcaca tagagtatgt agaatttgat
      781 aatgctatgg aagaagaaat acaatcaatt atgaaaatag agagagattt attcttggct
      841 attaaaaata aagagtttgt aattcactat caacctaaag ttgattcaag tacaggtaac
      901 attataggtt cagaggcatt gataagatgg ttgcacccat cattaggcat ggttggacca
      961 aataagttta tacctatagc tgaaaaaaat ggtctgataa acaatattgg tagatggcta
     1021 attcaagaag tttttattac cattaacaag tggatttcag aaggtataaa tgtcttacca
     1081 gtctcaataa atctttctag agtagaacta tataaaaatg atttagttga tttttttaaa
     1141 ctgatgttta atacatataa tattccaaaa gaacttatag aattagaaat tacagaaacg
     1201 acagcactaa gagatgtaaa atttataagt gaaaggcttt atgagattaa atctttaggt
     1261 atgaatatat cattagatga ttttggagta ggtaattcaa attttatcaa ccttaagggg
     1321 ataccactag atattataaa aattgatagg tcacttatat tggatatagt tacaaataca
     1381 aaaacaaagt ttatggtgaa agcaattgtt aacctttcac atgatttaaa cgtaactgtt
     1441 atatgtgaag gggtagagga tatgcatcag gtcaaagtct taagtgaact gggatgtaat
     1501 ttcatacaag gttatgtatt ttttaaacct ttggatgaga tgaattataa aaaacttctt
     1561 actgacggaa gttatataaa tctgaaagat actcttttag ataaatgcat gacagttgag
     1621 gaggagtaag gatgatttca gaagatgtag attattcaat aagaatcata agagctatat
     1681 ttaataatgg agaagataaa ccaatagatg ctaaaatgat attaaaaagt gaagatatac
     1741 caatactaac actatacaga ctgcttagaa agctttgtgc aaacaatatt cttactttta
     1801 acaaagaaga tggcaagaca tacatgttaa atgtgtcatt ggatacaata agtctaagaa
     1861 ctattgtaga agtaattgat ggaaaaatat atataaataa atgtacgaga tatgtatcta
     1921 attgcagtaa ttgcttaaaa ggttgtaaag taaatcgtga attgctagaa atagaaaaag
     1981 aaatttataa acttttatcg agaaaatcta taagacaaat actagaataa aaaattttca
     2041 gctatgataa taattggagg ttttcggtta tggatgatat atctcaagat aattttctac
     2101 tgtctaaaga gtatgagaat agcttagatg tagatactaa aaaagcaagt ggaatatatt
     2161 atactcctaa aataattgta gattatattg taaaaaaaac tttaaaaaat cacgatataa
     2221 ttaaaaatcc atatccacga atacttgata tttcctgtgg gtgtggaaat tttcttttag
     2281 aagtatatga tattttatat gacttatttg aggaaaatat atatgaattg aaaaagaagt
     2341 atgatgaaaa ttattggact gttgataaca tacaccgtca tatattaaac tattgtatat
     2401 atggtgctga tattgatgaa aaagctataa gtatattaaa agatagctta acaaataaaa
     2461 aggtagtaaa tgatttagat gaatctgata taaagattaa tctattttgt tgtgatagtc
     2521 ttaaaaagaa atggcgatat aagtttgatt acatagtggg taatccaccc tatattggtc
     2581 ataaaaaact tgaaaagaaa tataaaaaat ttctcctaga aaaatatagt gaagtttata
     2641 aggataaagc tgacttatat ttttgttttt ataaaaagat tatagatatt ttaaagcaag
     2701 gagggattgg cagtgttata actccaagat attttttaga aagtctatca ggtaaagatt
     2761 taagagaata tattaaatca aatgtcaatg ttcaagaaat agtggatttt ttaggtgcaa
     2821 atatatttaa aaatataggg gtatctagtt gtattctaac ttttgataag aaaaaaacaa
     2881 aagagacata tatagatgta tttaaaatca aaaatgagga tatatgtata aataaatttg
     2941 aaacattgga agaacttcta aagagtagca aatttgaaca ttttaatata aatcagagat
     3001 tgctatctga cgaatggata cttgtaaata aagatgatga aactttttat aataagatac
     3061 aagaaaaatg taaatatagc ttggaagata tagcaataag ttttcaagga ataattacag
     3121 ggtgtgataa agcgtttatt ttaagtaaag atgatgtaaa gttgaacctt gtagatgata
     3181 aatttttaaa atgttggata aaaagtaaga atataaataa atatatagta gataaaagtg
     3241 aatataggct aatatactca aatgatatag ataatgagaa tacaaataaa aggatactag
     3301 atgaaattat agggctatat aaaacaaaat tagaaaacag aagagaatgt aaaagtggaa
     3361 taaggaaatg gtatgaactt caatggggta gagaaaagct tttctttgaa agaaaaaaga
     3421 taatgtatcc ttataaatca aatgaaaata gatttgctat agattatgat aataattttt
     3481 caagtgcaga tgtatattct ttttttataa aagaagagta tttagataaa ttttcatatg
     3541 aatatctagt tggaatttta aattccagtg tttatgataa atactttaaa ataactgcta
     3601 aaaaaatgag taaaaatata tatgattact atcctaataa ggttatgaag ataaggattt
     3661 ttagagataa taattatgaa gagatagaga atttatcaaa gcaaataata tcaattttat
     3721 taaataagtc tatagataaa ggaaaagtag aaaaattgca gataaaaatg gataacttga
     3781 taatggattc tttaggtata taagcagttg taagtattaa aaaattataa tcttttaatt
     3841 gtttatttaa atttagaaat aaaaagttag ccatataaaa aatattaaaa atatatactt
     3901 ttcaatattt ttttgataaa ataagaatga atttgtgcaa ttttattttt ctccaataac
     3961 taaaaatagt tttttgaatt aatatttgct taagaataaa aatcagaaac gtttttgata
     4021 tagtaggtga taatatgaaa ggattagttt tagaaggtgg aggaacaaaa ggagcctacc
     4081 aaataggtgc atataaagct ttaagagagc ttggtataga gtttcaagga gtaactggca
     4141 catcaattgg tgctttaaat ggagcatata tagttcaaaa tgatattgaa gtaatggaag
     4201 atatttggtt aaattatgac tatactcatt ttatgaatat tgatagagaa acctatgaga
     4261 ggtttaaaaa tgtagatttc actactaaaa atctcaatgc agtgtttgag cttataaata
     4321 aagctagaaa aaatgaaggt atagatataa gcccattaag acaactaatg gagacaacat
     4381 taaatgaaga cataataagg aaatcaaaaa aagactttgg acttgttacg gtctggtggg
     4441 ataaaaaaat taatccatat ccattgtata tcgaagatat acctaaagga agattgattg
     4501 attatttaat tgctagttcc agtttgccta tttttcaaac gaacatgatg gatgataagt
     4561 tgtatcttga tggaatgttt tgtgataaca tgccaatagg actcttggaa gacaaaggtt
     4621 atgaagatgt tgttgtaatt aggttgattg atgattttat tgggaaaatg aatctaaatc
     4681 gacatcaaaa tataaatata aaaactataa taccatcaga atatctagga ggttctctta
     4741 ataaagatag agataatgta gaaaaaaaca tccgactagg ttacttagat actatgaaag
     4801 catatgaaag atgcactgga attaagtatt attttgatgt agagtataaa tataatgaag
     4861 aatattgttt tgataaattt agaagtatga gcaatgaaac aatacaatat atctgtaatt
     4921 tattgaatat aaaaagagat gcttcactta gaaccgttat ggaaagtgta ataccaaagc
     4981 ttggtgaggt gcttggattg ccaaaggatt tttcatataa agatttgttt tactgtatat
     5041 atgaaaagaa acttgaagaa aataatataa acaggataaa attatatgat tttaacaagg
     5101 ttatagatgt tgtaaataca aatattgatt ctaatagaaa tttagcttct aattttgaag
     5161 ttagacctaa aattagtatt aaaaagaaca aaaacacaaa attattgaca aattgtatta
     5221 taaaagacat aaaaaatcaa agttaaataa aaaacaaaaa aaaatttgta attatactcg
     5281 aaaaaagtgt atattagtag tataatattt ttgtagcact agtgggaaca aaaaatgacc
     5341 ataggacaaa aaagtaccac ttagtaccat taaagtaaaa aacaggaaaa caattttaaa
     5401 aaatataaaa tgtaaagttt ataggaggat ttaaaaaaat ggaaaaagta gttagtatca
     5461 aaaatgcaag tggattacat gctagaccag caggaatgtt tgttaagaag gcagctgaat
     5521 ttaaatcaac agtagaggtt gtagcaaaag acaaaactgt aaatgcaaaa tcaataatgg
     5581 gaataatgag tttaggttta gctcaaggag aagaattaaa gttagttgta aatggagaag
     5641 atgaagaagt agctttagct gcaatggttg aattagttga aagtggattt ggagaataga
     5701 tataataatt ttttaaaaat ttgatattta gaatctaata ttacttaaag taaagtaaca
     5761 gagaagtatt aaacatatac agaccaacat ttgtagatat ttaatttctt tgttactttc
     5821 atgtttattt aatcagaaga ttaagactat tgttaattgg gtataaaaat ataaatattt
     5881 tagaaaatga aataagatat ttttaatcat aaattcagag taaaaataca gtaacaaata
     5941 gtttataaaa ttttataaaa aattataagt aaataaaact ataaaaatgt aaattattta
     6001 tataaattta taaagtttat gtgctagatg atatttttta ggaggtaggg ttatggctta
     6061 caaaggaata ggtgcttctc ctggtgttgc tttagggaaa gcgttagtag ttgaacatag
     6121 tgaattagta attgaaaaaa aatctataga taatgttgaa gctgaaattg ctaaattaga
     6181 agatgcagtt gcagtttcta aagaagaatt agtaaaagtt aaggaaaagg cttctgaaga
     6241 attaggagca gaggaagcag aaatatttga agcacattta ttagttttag aagacccaga
     6301 gttaattggt tctgcaatag ataaaattaa aactgaaagt gtaaatgcag agtatgcttt
     6361 aaatgaaata aaagagatgt ttgttagcat gtttgagtct atggacaatg agtacatgaa
     6421 agaaagagcg gcagatataa aagatgttac aaatagaata cttagacata tattaggaat
     6481 taaagttgtt gatttatctg ctttaagcga agaagttgta ttaatagcac atgatttaac
     6541 tccatcagac acagcaacta tgaataaaaa aatggtttta ggatttttaa ctgatatagg
     6601 tggaagaact tctcatactg ctatcatgtc tagaacttta gaaatagctg caatcgttgg
     6661 attaaatgat ataacttcaa aagttaagga tggagatttt gtggttttca atggagacac
     6721 aggtgaagta atcgtgaatc ctgatgaaga gactataaat aaatatactg aattaaaagc
     6781 taagtatgaa gatgagagaa aagcattaca gctattaaaa ggaaaaccat ctgtaacttt
     6841 agacggaaaa catgtggaat tagctggtaa cataggaaca cctaacgata tagaaggtct
     6901 aataaagaat gatgctgaag gtgttggtct ttatagaaca gaatttttat acatggatag
     6961 agattctttc ccaacagaag aaatacaata tgaagcatat aaagctgtat tagaaggaat
     7021 ggatggaaag cctatagtta taagaacatt ggatataggt ggagataaag aattaagtta
     7081 tttaagtatg gaacctgaaa tgaatccatt cttaggttac agagcaataa gactttgcct
     7141 agatagaaaa gatatattta agactcaatt gagagcttta tatagagcta gtgttcatgg
     7201 aagattaaga atcatgttcc caatgatttc atctttagaa gagttgttac aagctaaaga
     7261 agttgtaaaa gaagttttag cagaacttga ttctgaaggt gtggcttatg ctaaagatgt
     7321 agaaattggt atgatgatag aagttccatc tgctgctgtg atatctgatg tattggctaa
     7381 acacgtagat ttcttctcta taggaactaa tgatttaatt caatacactt gtgcagttga
     7441 tagaatgaat caaaagataa gctatcttta caatcaattt aatccagctg ttttaagact
     7501 tataaagact gttatagaca atgcacataa agaaggcaaa tgggcaggta tgtgtggaga
     7561 atctgctgga gaccaaaaaa tgataccaat acttttaggt atgggattag acgagttctc
     7621 tatgtctcca atatcaatac ttcctgctag aaagttaata acttcagtta aagagtcaga
     7681 tatgaaaaaa ttagctgatg atgtacttaa tatgggtact gctgaagaaa taaaaagcta
     7741 tatagaaaag acttttaata tataattaat gttatatagt tactaaaatt catttttcta
     7801 aataacaaaa ttatatttta cgaattaaaa aggagatgtt tcaaaataaa aatttgaagc
     7861 atctcttttt tataaaagat tactaagaat tacttaatct ttgtaatagt cattttgtga
     7921 aaaagcaaaa ctgcattgtg gctatagtat atatggatgt tattatcaat aaaagtacta
     7981 ttaaaatgaa gattcattct caaatgatat caaaagtagt tgtgatggag taagataata
     8041 ttttgtgatt taatagtaaa aattaaaaaa atatggtatt gaaaaataat taaaagtatt
     8101 taataataga attagggaag aataagttta taagtaaaaa taattgatta ctagttaata
     8161 aaataaatgt gatatccaaa taaatcctaa atctaatttg agttttaata tagatagtct
     8221 aaagtttgat tattaaagat ttaattgtaa gttgttacag ttgatgatat tgattagaga
     8281 ttaaagttta gagtagaaag ttaccttaaa tttaaaaatg caagataacc caatctaaaa
     8341 attataatca ctcaataggt ttaaggattt atttgtttat tataaatagg agggtgtctc
     8401 aaaatgaact ttttagttta tgaggcactc tcttttatat agaattaaat atattttatt
     8461 atttcaacaa tgaaaaagaa gcttatctct attttgagac agcctctttg tatactatta
     8521 ttaatttaat caataacata atttaaaact atattattag ttaagatttc ctgctttatt
     8581 agtaaataat tctttaatag cattgtttct ggaaactaaa tcgttatcag agttgtttgt
     8641 ttttttcata atcactgaat aacgtttttt atttataaaa aatattaaaa tcttatcatc
     8701 atcaaaattg tattctttat atctgtcaat agactcataa cctagattta gaatgttttt
     8761 gtcttttata ctatctacat ctaaaatata tgatgggtca gcctttagta atatattaat
     8821 taaacatttt tcttcaccag cacagaataa ctccatctta cttgatatag atttagattg
     8881 ctctgaagtt atttttgcag gaataaggtt gtcattgtca tctcttagaa gataaccatg
     8941 tgtgtcttgt tgatatacta aattaacctt tttcttagga acactaatca ttttatctaa
     9001 atgtacataa tgatgatttt caacaaaacc ttcatttaat atttcaacaa agttattaat
     9061 tttacctagg caaaaagatt ctatagattc tttacagaat ttatttgtaa atggtattat
     9121 gtttacgttt tcctcgtctg tattccatgc tatagcataa tccaacgaat atacttcttc
     9181 ctctatatct gcaaaattat attgtactat gtttcctttc aaaattactc gacctccatc
     9241 ttataatata tttaatatac tttataaaac ttatattata tttaaataat atcataaatt
     9301 gaataaatat gatatagtaa ataagaaaaa atttgaaaaa aatcactata aatgagtaat
     9361 aaatataaat agtgtatact aatgggatgg aaaatgtcca ctattaactt tattacccca
     9421 catatataag ataaaattat taatataaaa tataatctat cgacaatgaa tagactttta
     9481 aataaactta atataaaatt aattaaataa gtgcttaaaa acgatttact ttaatgatag
     9541 aatcatatta aaggaggata attttatgga tataaagaat aaaattaaat ctatattttt
     9601 accagaaaaa aatgactatt tagatgatga agaatttgag tatgatatag aaaataatga
     9661 agaagattta aaggaagata acaaagtaca tttaaatgat ttaagcagag taaaatatga
     9721 ttacagagag ttaaaagaca tagaaaacca aacagaagag atgtgtctgc tagcagtaaa
     9781 gcaggatggt actataattg agtttgtaaa ggacaagact tataaagtat gtatggaagc
     9841 agtaaaacag acatataaat ctcttaagta tataacaaat caaaatgagg atatttgtat
     9901 agaagcagta aaacagaact acagagcttt gtactacata aataataaga cagaaaatgt
     9961 actaattgag gctataaaaa atgcatcaac ttatgatgtc atggaagtat ttaaatttgt
    10021 ggaagagcaa acagaagatg tatgtctagc atttatagaa agggcatcta aaaatgatgt
    10081 tgcagagata ttaaaaggaa taaaagagca aactccagcc atatgtttag aagctgtaaa
    10141 aaaagatgga aaatctttag cttatgtaaa ggaacaaagt aatagtatat gtttagaagc
    10201 tgtaaaagaa aactacagtg cactatcttg tgtaaaagag caaactgaag aaatatgtat
    10261 agaagcagta aaacagaatg actttgcatt gtattatgta aatgaacaga cagaaaaaat
    10321 atgcatggaa gcagtaaaaa gaagttatat ggctctacag tatgtaaata agcaaacaga
    10381 agagatttgt ttggaagcag taagaattga tggaagagca ttacagtacg taaaagagca
    10441 aacagaagaa atttgcttgg agtcagttag acaaaatgga aaagtactgc aatatgtaaa
    10501 aaaacagact gaaaatatat gtatagaagc agtaagaggt tcatttgaag aacttgaaat
    10561 aaaagaaata ttaagttatg taaagatacc aacagaaaga atatttgtag aagcagtaaa
    10621 gcaaaatgga aaaattctta aatatgtaga aaatcagaca gaattaatat gtttagaggc
    10681 agtaagagaa aactataatg ctttagctta tgtaaaggaa caaacagaaa agatttgttt
    10741 agaagcagtt aatcaaagtt atgaagcgct taaatatgtg aaagaacaaa cagaagaagt
    10801 ttgtctaaaa gcagtaaaac aagattatag aatgttgaaa tatgtaaata atcaaacaga
    10861 aaaaatatgt ttagaagcag taaagcaaaa ttatagagct ttagaatttg ttgataatca
    10921 aacagaaaaa gtttgtcttg aagcagtaaa acagaataga aaagcactac agtatgtaaa
    10981 acaaaaacaa agttaaaagg ctaaaatata tggggaatat atgcaaataa ataaaatttg
    11041 atattttgta ataaataaaa tgggtatctc aaaaggaact ttttagtttg tgaggtactc
    11101 tttttatatg aaatgaaata tatttttagc cttttaacaa aggggaaaag gtttgtttct
    11161 attttgacat aggcttttta tgcatataaa gcttgataaa attgttttat tataattgtt
    11221 ttgttatata aataataaga agaaaattat ataggtcttt ttttgaccag ttttacattt
    11281 ttaacaacta gttttgtaaa gtatattgaa ttttctcaaa aaagaatgta ctctatatat
    11341 gtaaaatttt tttggaggta aaaatgttta aaagatatgc tgaaaaaatg acatctgttt
    11401 taatttgtaa taatatgata gataataatg aatctaaagt ctattcttat ggatttgaaa
    11461 tattaatagc tttcatagtt aatataacca ccatgctgtt tataggtttt ttatttggta
    11521 aatttacata tgtattattt tttttaatgt gttattgtcc aataagacaa ttttcaggag
    11581 ggtatcatgc agacaattat tttagatgct tattaacttt tatttttata attttatcca
    11641 caatcttaat tatagaaaat ataaatatag acttatttaa aaatattatt atgattattg
    11701 caagtgttag ttgggttgga atttgtgttc tgtgcccaat agaacatagg agtaacccta
    11761 taagtgatag ggaaaagttg gtttataaga aaactgctat atttatatct acagtagtgt
    11821 tattgataac aatttcaagt ctttctttga gtatatttgt agattatttc acatatagcg
    11881 catttgccat gttttggatt tttgtgatgt tagtattagg taagttaaaa gctaaagtat
    11941 aagtaaaata tgtatgaggg agagttaagt tatgaaaaag tttattgtaa gatttatgaa
    12001 gtttgctagc tcattggcac ttagcactgc tattttgtca gctaatagta cctgtccttg
    12061 gattattcat cagcctaaag tacccaaaga aatcagcaat ctaaagaaga caaattaaat
    12121 acaagcactt atttatacaa aattatcagg aaaaaagaaa ttattatatt ttaataagat
    12181 taaaacaata taaaatcaga tacaaaattt attttatagg agcctaatac ctatttggta
    12241 atatattagt gcgccaattt agggggatat agtgtattta atgaaatgac ttacggagag
    12301 taagtcattt ttgtattgta tgtattttat gtaaacttat gatataatga agggtaaagt
    12361 ttaattaaaa taataaaaaa ctttagtata gatagtaatt taggaggtag ggtatgagta
    12421 tgatacataa attttctatg aatggatata atatcgtttt agatgtgaat ggtggagctg
    12481 ttcatgtgtt agatgatgtt gcatacgatt tgttagattt ttataaagaa aaaagtaaag
    12541 aagaaatatt agagatatta aaatcaaaat atcaagaaga aaaaataaat gaagcatatg
    12601 aagaaatatt aaatttggaa aaagagggtc ttttatatac agaagataca tatcaatatc
    12661 atccaagctt tgtacataga gagcctgtag taaaagcttt atgtttaaat gtagctcatg
    12721 attgtaactt aaaatgtaaa tactgttttg cagctcaagg tgattttgga ggagaaaaag
    12781 aacttatgag ttttgaagtt ggtaaggcag caattgacta tttgattgct aattcaggaa
    12841 gtagaaagaa cctagagata gatttctttg gtggagagcc tttgatgaac tttgaagttg
    12901 taaaacaact ggttgactat ggaagaagtg tagaaaaaga ttataataaa aatataagat
    12961 ttacaataac tacaaatggt gtactgctaa atgatgagat tatagattat ataaatgaaa
    13021 atatgcataa tgtagtttta agtttagatg gaagaaaaga agttaatgat aatatgagac
    13081 caactttaaa tgataaagga agttatgata ttacattacc acgatttaag aaacttgtgg
    13141 aaaaaagagc aaaagataag tattattata taagaggtac ttttacaaga gataatttag
    13201 atttttcaaa agatgttatg cattttgcag atttaggatt taaattaacc tctgtagagc
    13261 cagtcgttgg agatgagagt aatccatatg cacttagaga agaagattta cctaagatat
    13321 ttgaagagta cgaaaaattt gctgtagagt atgcagatag acaattacaa ggagatggat
    13381 ttaaattttt ccattttatg atagacctaa atcaaggtcc atgtgtaata aagagaataa
    13441 ctggatgtgg agctggaaat gagtatcttt ctgtaactcc aaatggagat atctatccat
    13501 gtcatcaatt tgttggaaat gaagaattta aaatggcaaa tatatttgat gaagaaatag
    13561 tacttccaga aaatttaaaa aatatgttta gagaagctca tgtatatact aaagaagagt
    13621 gtaaacaatg ttggaataag ttttactgtt caggtggatg tcatgcaaat gcgataaact
    13681 ttaataatga catatcaaaa ccatatgaat taggatgtga aatgcaaaga aaacgtacag
    13741 agtgctctat aatgatacaa gctaagttaa tgttagaagg agcaaccaac taaatttata
    13801 ttttaaagga gttgtttata tatgattaga gattatttag aagataaacc tttaattgac
    13861 gaaagtgtat ttgtggcaaa atcagcagat gtaattggaa atgttaaaat aggcaaagat
    13921 tcaagtatat ggtacaatgc agtagttagg ggtgatgaag gaccaataac tattggagaa
    13981 aacactaata tacaagattg ttctatagtg catggagata cagaaactat aattggtaac
    14041 aatgtaacag ttgggcatag gtctatagtt catggttgta aaattagtga taatgtgtta
    14101 attggtatgg gttcaataat attggataat gctgaaatag gagaatatac tctgatagga
    14161 gcaggtacac taattacatc taataagaag tttccgccag gtgttttgat aatgggttct
    14221 cctggtaagg ttgttagaga gcttacagaa gaagataaaa aatatattga tgaatcttat
    14281 gaatggtatt tagaggcagc acaaaatcaa aaatattagt ttaaagagtg gttgtttcaa
    14341 aacatattta aatctgtttt gaggcaacca ctaatttatt ttattagatt ttgttgatat
    14401 tttagttttc aaaaagtatt tgattaaacc agatataaaa tgtcaaaaat aaaaattaac
    14461 tgagttaaat aattttaata aaattggtag tatatgtgat aaaattaaat attaaagagg
    14521 atataggata ttagaatatc aattggtgaa ataatgtcat atacgataaa ttaaggtgta
    14581 agtttttggg tatacctatc ttaggagtga aaagatttga gaataagtta tagaaattta
    14641 aagcgatata gagaaattgg atatgtttta ataaagtatg gttttagttt tattgtagaa
    14701 agactaaata tagaaggaat tgcctataaa ataccactat ttgacccacc agaagaaata
    14761 aaaaatatga caactggtga gagaatgaaa agagttttag aagaactagg acctacatat
    14821 ataaaaatag gacagatatt gagtacaaga aaagacttgt tagaccagga tataattgat
    14881 gaaatatcaa aactcagaga tgatgtagag aaatttgatt caaatatagc tattgatata
    14941 tttaaagaag aagtgggttt aagtatagaa gaaatattct tagaatttaa agaagaagca
    15001 atagcagcag cttcaattgg tcaagtttat gaaggtgtac ttaaaacggg agaagaagta
    15061 atcgtaaaaa ttcaaagacc aaatatagag aaaataataa aatctgattt agagattctt
    15121 agaactattg caaatacttt aaaagattta aaaaaggatt ttaatttaga tttagtacag
    15181 atgattgaag aatttcaaac tcaattaatg agggaacttg attatacatt tgaagctata
    15241 aatgcaacta aattctctag gatatttaaa aatagtgatg aagtatatat acctaaagta
    15301 tattcagaat ataatactaa gaaaatttta gtaatggaga aagttaatgg tacaaagtta
    15361 agtgatgtag aaaaaataag gagactaggt tataacacaa aaactattgt tgaaataggc
    15421 gttaggtcat tttttacaca ggtattatct catggatttt ttcatgcaga cccacatcca
    15481 ggtaatatat tcgtagttgc taaaaataag atagcatata tagattttgg aatgattgga
    15541 attattgata ataaaacttt aaaccaatta aatgaaattg cattagcagg tgtagaaaag
    15601 aatgttgaca agataatata tctattgata gaaatggatg cattaaatgg agaggctgat
    15661 attaagggac ttagacagga tttactttat ctaatacatt attactatga tatttctata
    15721 gaaaaaataa atgtaacaga tatattaaat gaactattta ggttttttag acagtataaa
    15781 atagtcatgc ctgcacaatt tgtaactctt gcaaagacag ttataacatt agaaggaaca
    15841 agtagaactt taaacacaga tttttctttt ggttctatgg gaaaagagtt tatgaaacat
    15901 cattataaga gtaaatttaa ccctaaaaat gttgttttaa gttcaagaca aaatgtagaa
    15961 gaaatattac tggacataaa aactattcca aagcaattaa aagcaatttt aaaaaatata
    16021 gaaagaaata atataaaaat gcaaattgaa gatgttaaaa tgacgaggtt agaaaattgt
    16081 ataatagagc taacatctca aatatctttg agtttagtgt tggcatctat tatagtaggt
    16141 tcttctctta taattgcatc tccaaatata gaaaataata tatggataaa atttactgca
    16201 atagcgggtt tctttatatc ctttataata ggcctttgct tagttataag aagtattagg
    16261 tcaaaataca aaaaagatta gggggaatta aatttgaaaa aatggatatt gaagtataaa
    16321 ggtaagatag aggaaagtga atttagcaaa aaacttaata tttccccgga aatctgccaa
    16381 attttaaaaa atagagggat atgtactgaa aaagattcag agatatttat gaatccatct
    16441 ttagattatt taagagaccc ttttttaatg aaagatatgc aaaaagctgt tgatagaata
    16501 aagttagcag ttgagaagaa cgaaaaaatt tggatttacg gagattatga tgttgatggt
    16561 gtatcatcta catctatctt gtgcttatat tttaagagta taggttacaa tgttgattac
    16621 tatattccta atagattaga agaagggtat ggtataaatg aagatgctat taagcttata
    16681 agctctaggg gatgtgactt gattataagt gttgactgtg gaattacatc agtgtctgag
    16741 gtcaatacag cgaatgattt gggcatagat gttataatta cagaccatca tgaatgtcaa
    16801 agtgaaattc catcagcctt tgcagtaata aatccaaaac aagaagattg taattatcca
    16861 tttgattcac tatgtggatg tggtgtagca tttaaaatga ttcaagcctt gactccaaaa
    16921 gaagaattta aaactagtat gtataattat ttggaaatag taacactagc aactatttgt
    16981 gatattgttc cacttataga tgaaaataga ataattgtaa aaaatggttt aaaatcaatg
    17041 aaagaaggca aaaatattgg attaagggag cttataaaag tttgtggtgt agaaagtgat
    17101 aagataggtt cttctcatat aggttttgca ataggtccta ggataaatgc ttcaggtcga
    17161 ttgggatatt cttacttagg agtagagcta tttactactc aatcacaaga agaggcagta
    17221 gaaatagcta gtatattgga agaaaaaaat aatgaaagac agatgataga agctaagatg
    17281 tatcatgaag ctgaggaaat gctaaagtct aatagcagat acaatgatga caaggtgttg
    17341 gttttagcta aagagggttg gcaacatgga ataataggaa ttgtagcatc aaagttaact
    17401 gaaaaatact acaaaccaac aattcttcta ggtatagaaa atggggaggc tactggttca
    17461 gcgaggtcaa taaaaggatt taatatattt gaagctctca taaagtgcaa agacttgatg
    17521 actaagtttg gtggtcatga acaagcagca gggttatcct tggattcaga caatgtagaa
    17581 attttagcaa atgaaataaa taaatttgca gattataatt taactgaaga tgatatgata
    17641 gagaatgtaa atgttgagtt tgaattacaa gaaaatgtaa taaatttaaa tcttgtagaa
    17701 gaattacata agttagaacc ctttggatta aataatccta atcctagatt tatagttaga
    17761 aattatattt taaaagattt gaaagttata ggtaagaatc aacaacatct gaaattaagc
    17821 atagaaaaag agaaaagcta tgaatgtata ggatttaata tgagtcattt aaaatcaatg
    17881 tataaagtag gagacaaggt agatgtacta ttccaattag atgaaaataa ctatatggga
    17941 aataggaaag tacaattttt acttaaagat atacgattgg ctcgacctaa aagtgcaagt
    18001 aatgacaaac tttcattgaa attaatgtca aaaataatac caaaagatac tcaaagcctg
    18061 tataatatat ctgtgtctga ttttgaatta tttgatggaa atacagatat aaatatattt
    18121 gattattttg aaaaagatac actaataata tctaattcta taaatggatt ttatagagca
    18181 atgtcagata tatcacttat agatttggat tttaacataa attacaatat tattgaagat
    18241 gttagcaaaa atactgataa attagagctt atattttctc ctaatattga taaaatagac
    18301 ttaaaaagat ataataatat tattctttat gattatttat acaataaagg cgaatattcg
    18361 tatatatatg agaataaaag agaagaaagt gaaattataa aatattataa taaaacagac
    18421 ctattatatt taaagaatgt agttagtaat atagttccat caagagatga atttataaca
    18481 atttataaac aagcactcat aaaaaaagaa attgatttgg atatggtaaa tataagggaa
    18541 acttttaatg taattccatt aaagtttttt acgatattaa atgtatttag agaattaaat
    18601 ttacttgact ttaatttaaa ttatgaaaaa aattctgtac tcataagaat attgccaaaa
    18661 ccacagaaaa aattagactt aaatgagagt ttaatactca ataatctaaa aaatttagaa
    18721 aaacaataca atagcagtta ttaggaggcg tttcccatgg atttaaaaaa ctttataagg
    18781 aatattgatg atttcccaaa gccaggcata gattttaaag atgtgacaac tctatttaaa
    18841 gatggagatg catttaaata tgcagtggat tctatagttg aagaattgaa agataaagat
    18901 gtagatttag taataggacc agaagcaaga ggatttttga tgggtacacc tgtagcatat
    18961 gctttaggag taggatttgt tccaattaga aaacctggaa agttaccagg tgaagttgag
    19021 agttatgagt atggattaga gtatggtaca gatactttag agatacataa ggatgcaatt
    19081 aaaaagggtc aaaaagtagc aatagtagat gatttattgg ctactggtgg aactatggaa
    19141 gccgctgcca agcttgtaga aaaattaggt ggagaagtag tttctatgca atttttgatt
    19201 gagctaaaat tcttaaatgg gagagaaaag ttgtctaact atgatgttaa ttctcttata
    19261 aaatactagt acttttataa tagttggtat aacaccaact attttcatat atattaaaat
    19321 tttatacaaa ataggtggtt atatgcatga taaagaatta caagaaataa ttgaaaaaat
    19381 aaaagtttat gcacctaatg caaattttga aatggttgaa aaagcctata atcttgcaaa
    19441 aaaagcgcat gaaggacaat atagaaaatc tggggaacca tactttattc atccattagc
    19501 agttgcaaat attttaatag agatggaatt agatattgaa actataacag caggtttact
    19561 tcatgatgtt gtagaagata cagaatatac ctatgaagac ataaaaaaag aatttggcaa
    19621 agaagtagcg gatttggttg atggagtaac taaacttggt caaataaaat atcgttcgaa
    19681 agaagaaact caatctgaaa atttaagaaa aatgtttttg gcaatggcga aggatataag
    19741 ggttatactt ataaaacttg ctgatagatt gcacaacatg agaacattaa aatacatgcc
    19801 tccagaaaaa gcaaagtata aagcaaaaga gacacttgaa atttatggtg gtatagctca
    19861 tagattagga atttccaaga taaagtggga actagaagac agagcattaa gatttatgga
    19921 cccagaaggg tattatgatt tagttagtag agtatcaatg aagagaagtc aaagagagga
    19981 ttatattcaa ggaattgttg aacttcttaa agataagttt aaagatttaa gtataccatg
    20041 tgatgtatat ggtagaccaa agcattttta cagtatatat agaaagatgc aaaaaaaaca
    20101 taagactttt gaagagattt ttgatttaac agcagtaagg atattggttg ataatgtaaa
    20161 ggattgctat gcagtacttg gtatagttca tacattatgg agacctattc caggaagatt
    20221 taaagattat atagcaatgc caaaacccaa tatgtatcaa tcattacaca ccactgttgt
    20281 aggtcctgat ggagaacctt tagagataca aataagaact catgagatgc ataatatagc
    20341 tgaaaatggt atagcagccc attggaaata taaagaaggt atctctagca aagaatcaaa
    20401 ggttgaagaa aaacttcaat ggttgagaca gatgatggag tgggaaaaag atttaaaaga
    20461 cccacaagag tttatggatg cacttaaaga agatgtattt aatagtcaag tttatgtatt
    20521 tacgccaaaa ggagacgtaa ttgaattacc agcagaatca acacctatag attttgccta
    20581 tagggttcat acaaatgtag gcaataaatg tgtaggagct aaaattgatg gaagaatagt
    20641 tcctattgat tataagcttc aaaatggtaa tattgtcgag gtacttacat catctaattc
    20701 taatggacca agtagggatt ggcttaatat agtgaagacc ccaaatgcaa aaagtagaat
    20761 tagacaattt ttcaagaagg aaagaagaga agaaaatgtt gaccgtggaa atacaatatt
    20821 agaaagagaa tttaagaagc atgatatacc acaaaaagac cctcttgttg aaaaatatat
    20881 ggcattagtt gctaagaaat ttaatcagcc aagtgttgag gacttaattg ccactgtagg
    20941 ttatggtggt ataatgtcat ctcaagtggt atctaaggta aaagacctat atttaaaaga
    21001 ggttaaaaaa gctaaaaagg aacaacagat acaagaagaa gatttaaata aacacaatat
    21061 aagtgaaaca gaatacagta aaaagagaaa gaaaaacgca tcacaaggaa ttatagtaaa
    21121 agggcttgac aatatcttag taagatttgc taagtgttgt aatcctcttc caggagatga
    21181 aattgtagga tatattacta agggtagggg agtagccata cacagagctg attgcccaaa
    21241 tgcaaacaat aatggtgatt tcttccaaaa tagattggtg gaggtttcat ggagttcagc
    21301 aggaaaaggt aagtttgaag cggaaattca aataaaagct attgatagaa gaggaattgt
    21361 taatgaaata actcatattg ttgcaatgga taaacttagt ttaaacggaa taaatgcaag
    21421 aaaaggtaag gatagtattg taagtataaa cttacttgta gaggttaatg acacagagga
    21481 attaaaaatt ctaatgaaaa aattaaaagc aattcctggt gtagaaagta tttatagaat
    21541 gacaaattag agttaaaata atagggagga aactatgaga gcagtagtgc aaagagtatc
    21601 ttcatctaaa gttacagtag atgaaaacac tataggtcaa ataaataagg ggttactagt
    21661 attgttagga gtgactcatg atgataaatc aagtgatgta gattatatga ttgataaaat
    21721 attgaatctg agaatttttg aagatgaaaa tgacaagatg aatttatctc taatggatat
    21781 aggtggagag cttttagtag tatctcaatt tactttatat ggagattgca gaaaaggaag
    21841 aagacctgga tttagtaatg cagctaggcc agaacttgca aataaccttt atgaagaatt
    21901 tgtaaaaaaa gcaaaagata aaggtgtgac agttggtaca ggtcaatttg cagctcatat
    21961 gatggtagag ttaactaatg atggtccagt aacaatacta ttagactcaa gtaaatcttt
    22021 ttaaggggga aaactttaat gattataaaa aaatttgtag atagttattt tggagtaaat
    22081 acttatgtat taggtgatga aaagactaaa aaatgtgcag ttatagaccc aggtggaagt
    22141 ttagtagaga cattaagttt tgtaaaagaa aatgaattaa atattgaata tattatcctt
    22201 actcatgggc atggagacca tataggatat gttaaggata ttaaagaaaa aactggtgct
    22261 aaagtagttg cacatgttga tgaaaaagaa ttattaaatg acaaaaataa aaatctaagt
    22321 tatacaatga gatgtggagc gcaagagttt gatgcagata tctatgtaaa tgataaagac
    22381 aagcttgaac ttggtgaatt aaaaatgact ttcttgcata ctccaggaca tactcaagga
    22441 tgtatgtgta taagagttga agatgaaatg ttcacaggag atactttgtt tgctggaagt
    22501 attggtagaa ctgatttata tagtggagac tttaaccaaa tggaaaaatc acttaagaaa
    22561 ttatgtaaat atgaagatgc tgttagagta tatcctggac atggaccaac cagtactcta
    22621 ggggttgaaa agaagacaaa tccttacatg taattttata ttagtattta aaaaagtata
    22681 aaatatttaa taactatatt agtgaggggg ttcttctact gttaaataga aggagttaag
    22741 ttgatgttgt atgttttttt aaaaggacat gattataagt atgaagtagc agaacttata
    22801 aaattgttta ctagtgaatt taagtttaaa gactctaatg ctaacaataa tatagagtca
    22861 aagcatttaa taaatagatt gatttatgag aatggtgtat tattctcaag tactgaatac
    22921 tatgaaaatg gaaacttaaa gtacgagtca atacagaata tagaaaatat gaatcttgaa
    22981 tttttagatg gatttgatag cagcaaaacg attgaagaat ttcttaatag cctagatagt
    23041 gaaagtaaga ggaactttaa aaagctgtgt aaagaaaata tcaaaaaaag catgttttta
    23101 gtgcttaaac aagtatttaa ttcttatgta ccatggggaa ttttgactgg tattagacca
    23161 gtcaaaattg tccacaattt aatggataaa aagctagatg ataatagcat aagaaccatt
    23221 ctaaaagata attattttat aatagatgag aaaatagatt tagctcttga aatagctaaa
    23281 agagagcgat tatttatgta tcctatagat aaaaataaaa tttctcttta tgtaagtatt
    23341 ccattttgtc caactagatg tgtatattgt tcatttcctt caaattcatt aaaacaattt
    23401 ggacatttaa aaagagaata tgtttataaa ttgattgaag aaattaaggg gtttgccaaa
    23461 gttattaagg atactaagaa agaagttgaa actctatata ttggtggtgg aactccaact
    23521 acacttgatg aggaagaatt ggatttgctt ataaattcat tgttcaatga attagattta
    23581 agtaaaatta aagaatttac tgtagaagca ggtagacctg acactattac agaacaaaaa
    23641 ctaagagtgt taaaaaaaca caatgttagt agaattagta taaatcctca aactatgaat
    23701 gatgatacct tggtaaagat tggaagagag catagagtat ctgatttagt agattgcttt
    23761 aatatggctc gtagaatggg atttgataat ataaatatgg atataatttt aggtcttata
    23821 gatgaagact taaatatggt aaagaacaca ttggaggaga taaaaaaact ttctcctgaa
    23881 agccttacag ttcatacatt agccataaag agagcatcta acttaaatat aaatatggat
    23941 aggtataaag aacatctaac acaatatgaa gaaatggtaa aaatgataga tttatcaatg
    24001 aaatatgcaa aagatatggg attaaatcca tattatatgt acagacaaaa acatatgttg
    24061 ggaaatttag aaaatatagg ttatgctaaa gaaggatatg agtgcattta taatatacag
    24121 attatggaag aaaaacaaag taactatgca ttaggtgcag gtgctatatc gaaatttgtc
    24181 tatgtagatg aagatagaat tgaaagagta gaaaatgtaa aaaatgttga acaatacatt
    24241 gaaagagtag atgaaatgat aaaaaggaag aaagaagagg tatataaaaa tgttgactaa
    24301 agctcctaga ggaactaaag acataactcc aaaagaggct tacaaatggc gttatgtaga
    24361 aaataaattt agagaaatat gtgctttata tggatatgaa gaaatggtaa cacctatatt
    24421 tgaacataca gaacttttca agagaagtgt tggagatact acagatatag ttcaaaaaga
    24481 aatgtattct tttaaagata aaggtgatag agaaattacc ctaaagccag aaggtacagc
    24541 aggtgtagta agagcattta tagaaaataa attatatgca gatactcaac caacaaaatt
    24601 attttatgtg acaccttgtt ttagatatga aagaccacaa gctggtagac aaagacaatt
    24661 tcaccaattt ggaatagaag cacttggaag tgatactcct tcaatggatg ctgaaataat
    24721 cgcactagct gttcaatttt ttaatgaagt tggattaaat gatttggtag tgagtataaa
    24781 ttcagttggc tgtccagttt gtagaaaaga gtacaatgct ttattaaaag agtatcttga
    24841 ctcaaaagct gatatattgt gtgatacttg caatgagaga agagaaaaaa atccaatgag
    24901 ggttatagac tgtaaaaatc ctacatgtaa agaaaatatc aaagatatac catttattgc
    24961 agaccatttg tgtgatgatt gtaaatctca ctttgataaa cttcaagaat acttaaagga
    25021 aatgaatata aactttgtaa ttgataaaac aatagttaga ggcttagatt actatagaaa
    25081 aactgctttt gaaattatat ctaatgatat aggagctcaa agtactgtat gtggtggagg
    25141 aagatatgat ggtcttgttg aacaattagg aggaccaaaa ggtataagtg gaattgggtt
    25201 tggactagga attgaaagac ttttacttac acttgaaggt aatggaattg aaatagaaaa
    25261 ccctcaatct acggatatat ttatagtaac tataggtgaa gaagcaaata caagaagctt
    25321 taaattgtta aaagacttga gacaaaatca tataagtgca gataaagacc atatagagag
    25381 aagtgttaaa gcacaattta aatattcaga taaaataaat tcaaaattta caatagtaat
    25441 tggagatgat gaacttaaaa atgacactgc gacattaaaa aatatgaaaa catcagagca
    25501 aactactgta aaattaagta cattagttga agaattaaag caaaagctgt aaaataagaa
    25561 agtatgatgt tttgtgtatt agataaatat atagcattaa aattaaataa aatggaggta
    25621 gtatcttgga aactttaaag ggtttaaaga gaactcacta ctgtggagag ttgagagaaa
    25681 aaaacataaa tgaagaagtc gtacttatgg gatgggtaca gaaaaaaaga aatttaggtg
    25741 gtcttgtatt tgttgattta agagatacaa gtggattatg tcaaatagtt tttgatacag
    25801 atgtagataa agaagctttt gaaaaagctg aaaaattagg ggctgaattt gtaatagctg
    25861 taaaaggaaa agtatgcgaa agacaatcta aaaaccctaa tatgccaact ggtgatatag
    25921 aaatatttgc aactgaactt agacttttaa acaagtcaga aactccgcct atttatataa
    25981 aagatgatga tgatgtttct gaagcactaa gattaaaata tagatactta gatttaagaa
    26041 aaccatctat gcaaagaaat ttaaaattaa gacataaagt aatgaatatt acaagaaatt
    26101 acttatcaaa caatagattt tgcgaaatag aaacaccatt tttaatagct ccaacaccag
    26161 aaggagcaag agattatcta gtaccaagta gagttaatcc aggaaaattt tacgcattac
    26221 cacaatcacc acaattatat aaacaattat tgatggtaag tggtatggat agatatttcc
    26281 aaatagttaa atgctttaga gatgaagact taagagcaga tagacaacca gagtttacac
    26341 aaatagactg cgaaatgtct tttgttgagc aagaagatgt tatgagtatg attgaaggtt
    26401 tgcttgaagc gatatttaaa gaagttttag atgtagaatt ggcacttcca cttcctaaga
    26461 tgacttatgc agaagctatg tctaaatatg gttcagataa accagatact agatttgggt
    26521 atgagttaac agatatatct gatgttgttt gtaactgtgg atttaaagtg tttgctgatg
    26581 ctacacaacc aggaaaaagt gttagaggta taaacgtaaa aggcaaagct gacgacttta
    26641 ctagaaaaca aatatcatca ctagaagaac atgctaagac atatagagca aaaggtcttg
    26701 cttggatgaa agtaggacaa gaaggagtaa cttctccaat agcaaaattc ttcaatgaag
    26761 aagaaatgaa cgctatactt acaagaatga atgctgaagt aggagattta cttttatttg
    26821 tagctgataa aaactcaata gtatttgatg ctttaggaca agttagactt gaagtagcaa
    26881 ataggcttaa tctattggat aaaaatgtat ataacttact atgggtaact gagttcccag
    26941 tttttgaaga agatgaagaa acaggcacat tctcagcaat gcatcaccca tttacatcac
    27001 ctatggatga agatttagac aagttagaag aaggtgataa gtcatcttta agagcgaaag
    27061 cttatgatat tgtattgaat ggttatgaaa taggtggagg aagtgttaga atatcaaatt
    27121 ctgatgttca atcaagaatg tttaaagcac ttggttttac agaggaaaga gctaatgaaa
    27181 agtttggtta tttattagaa gcatttaaat atggtactcc tcctcatgct ggtctagctt
    27241 ttggtcttga tagacttgtt atgttacttg caggaactga taatataaga gaagttattg
    27301 cattccctaa aaatcaaaat gctgtttgcc ctatgacaaa tgctcctaca ttggcggaag
    27361 atgagcaatt agaagaatta agtataaaag ttgatataaa agataatgaa taatatgtag
    27421 ttgcaagaaa ctaaaatgta aaaagtctgg atataaaata tatttatatt cagacttttt
    27481 ttattagaat tattttatat tttttctcta tatattttca taaattatac ttatattctt
    27541 aaccaatata attaaaatac tatgtttaaa aattttacat aaacttggtt gttttagaaa
    27601 ctacttctgt aacgagtaca cgattttaat taaagaatat ataacaaatt tgaaataagt
    27661 ctaatatatg acttaataga ttaaattaaa ataataaatt tggactattt atctatttat
    27721 aacttaaatt atatcaaatt gataacaaac tagatattat acttttttgt agaatagaat
    27781 tacaattata taaagaaaaa ttctattaat agtgaaaaaa aagtagaaaa aagtagaaat
    27841 tattctttta taaagaaagg gagggataat attgcaagag agagaagaat tagttttaaa
    27901 tccagttcca aaagaggaaa gagttggatg gttagctcca ttgtttaata tgcttggttc
    27961 taacatagct atatctgaac taatggttgg gggaacttta attttaggaa tgactctttc
    28021 taatatgatt attacatcaa ttatagggaa cttaatatta gttgcaatta ttatgataca
    28081 aggttatata ggttacaaag aagggttaaa tacgtatgta ttagctaagg gggcatttgg
    28141 agagatagga ggaaagtatc ttatatctct attacttggt ataactagtt ttggatggtt
    28201 tggtgtacaa gcaggggttg caggactatc agtacaaaag atattcccaa gtgtaaacct
    28261 aacattagtt acagttatac ttggattatt tatggttgtt tttgcactgt atggttttaa
    28321 agctatggct aaatttaatt acttagttat accaccactt atgatattaa tggtgtgggg
    28381 agtttttaaa gctttttcta cttatggagt tgaagctatt tataattata ctcctcaaac
    28441 aactatgagt atggttgaag gtcttaatat tgtagtaggt cttgttatag ttggtgcaat
    28501 tatatcacct gaccagttaa gatatacgag acgagtaaaa gacatttgga ttatcagttt
    28561 tttaggtcta gggattattt cattattcca acaagttgca gctggtgtaa tgtctatggg
    28621 agcacctact tgggatataa cagaagtatt ggctaattta ggttttggat gggtagcgtt
    28681 tgttatttta atacttgcat cttggtctac aaacgtatca aatgcttatt ctggtggatt
    28741 agcattaaaa actatttttc caaatgtaaa aagaaatgtt ttgactttag ttgcaggtct
    28801 aataggtaca ataatagcag ctactggtat aatatttaaa tttcagtcat ttttatcttt
    28861 cttgggaatc gcagttcctg caatagcagg aattatgtgg tgtgagtatt attttataca
    28921 aggaagaact tataagcata gagaaggaat aaattggatt gcagtaataa gttggttaat
    28981 aggttttgca gcgtcgtatt atagttcaaa aataaatttc ttaatacctc cgataaatgg
    29041 aattgtagtg agtatggtta tttattatat attaatgaat tgttttggaa tcaaagataa
    29101 ataaaggggg caattacatg ggtcgtaagg tgaaaatagg tataattcaa caacacagtg
    29161 tacttggaaa tgttaaaaaa aatatagaaa aagcagtaga gatgatagat gacttaggaa
    29221 aacaaggggc agatataatt tgtttaccag aactatttgc tacaggatat aatttagagt
    29281 ctttaggtgg agttaaaaca ttagaattaa taagagaaca taataagtac atagaggaat
    29341 caatgtcaga agctgctaaa agaaataatg tatacctgat atctccatat ggaaccttag
    29401 aaaaagggtc tacacatgtt tataattcag cagttatatt tgatagaaaa ggtaagatta
    29461 tgggagaata ctgtaaaaat catctgtggt cattagaagc agtatacttt aaaggagggg
    29521 aaaaagtaga ggtatatgat gctgattttg gtagatttgg tgtaatgata tgttatgatg
    29581 caggttttcc agaagtatcc agagaattga cattaaaagg ttctgaaata atatttatac
    29641 catctgcatg gagaatacaa gatgaagata tgtgggattt aaatgtatct caaagagctt
    29701 tagagaacac tgtatataca gtaggtgtaa atttagtaag taatgactct aatttaatac
    29761 tatttggaaa gagtaaaata tgcaatccta gaggtactgt aataactcaa ttagatacat
    29821 acagggaaaa atatgtatta tcagagattg atttagatga aataaaaaag tatagggaag
    29881 atatccccta tttgaaagac agaaaaagta gctataacat ataattctat actataatac
    29941 aagttcaata taaaatgata aaaagaggat gtatcaatat taagattaaa tttattatac
    30001 tttgatatat cctctttaat attatcaact ttgatttaaa tatttttaaa atagttgata
    30061 agaaagtttt tgaacaacaa cacagcttta gattcatagt tttcgctaaa ccatgaaaga
    30121 tttaaatatc ttttaaattc aatatctttg atatgtaaca acttaatctc agggtcttga
    30181 gataatcccc atgattttcc acatataaat ccaactcctt gaagtgattt tataagagca
    30241 taaattgtat atggtgaatc agactcaaat gctattttgg gtttgaaatt agctgattcg
    30301 cacaggatat caattacctc tctataattc tcacccttcg ttataactat aaagttttca
    30361 tctgaaactt cgcttagata tacttcatcc tttaatgata aaggatggtt tattgaaact
    30421 cctaatagta tttcttcgca tgttaaagtt atgctatttt ctgagtttag ctttgtaaat
    30481 gaagaagata tgtacaaatc aaaatcactt tttttataag atgatggcaa agtatgtgac
    30541 acattaaaag taatattggg atatagtttt ctgaaattac tcaaaagtga tggtaacaca
    30601 ttagccgctg caggagataa tatctttact tctcctgaat tttccaaaga agtgtcttgt
    30661 aactcctttt ttgaactttc tactaaatct aaaatgctat ctactctttt tagaaacaat
    30721 cttccatact catttaaaac aatatatctt ccttttctgt caaataactg aactccaagt
    30781 tctttttcta aggaagatat agttttgctt aaagctggct gtgctatatt taacttgtgt
    30841 gatgcttttg ttatgtgctc cattctagca acagtttgaa aatacttaag atgcaataaa
    30901 tccatagtat aaaatacacc tcttttaata tgacttgagt tatatcaatt ttataatcaa
    30961 ctccacatta tacattataa tataaagttt atataataaa ctacaatata ttaaaaagtt
    31021 atttaaattg ttatttatat tttgtacata atctaattaa aaaaagtaac tttaaatggt
    31081 taactaagga aatattgtta caaactttag ttatataaaa aattcgtttg atgagcaaag
    31141 tattaatgtc aagtaagaat aaaagcttat tagataagaa aaataatatt ttataataat
    31201 gatgttactt aaattattat gttatactat tttaaatagg aaacatttag atactataat
    31261 tttaggggga gtcaagatga aattaactaa atcaatatca tcaatgctgt gcttatctct
    31321 agttttaagc ttatcaccag tagcatatgc aaatgaaata agtagaacaa cagttgagaa
    31381 tactttagta ggtcaggata gatatcaaac tgctgttgaa gtaagtaaaa aaggatggag
    31441 tagtgcaaat gaggctgtag ttgtaaatag tgaatctatt gtagatgcat tagctgtaac
    31501 accatttgct aaattaaaaa atgctcctat attattgaca gaaaaaaata atctaaattc
    31561 acaaactgag aaagaattaa aaagattagg agttaaaaaa gtttatataa ttggtctatc
    31621 tagttctgta tcaaatgatg tgcaaaaaca gttagaatct aataatttaa ctactgatag
    31681 agttggtggt agtgatagat accaaacagc tttgagtata gctaaaaaaa tagaaggatt
    31741 aaaagatata tcagaaatag ctgtagtaaa tgggtacaca ggtcttgcag atgcagttag
    31801 tatagcttct gtagctgcta ctaatggaat ggttatactt ccagtatctg atgcatctgg
    31861 tatatctagc tttaaagatt ttatagaatc taagaatata aataaatcat acataatagg
    31921 ctctactaat gctgtatcag ataaaataaa acaaagttta cctaattcag aaagaatagg
    31981 tggagcagat agaaatgaaa ctaatggtaa agtaatagaa aagttttata catctaataa
    32041 attaaacaat gtatttgtgg ctaaggatgg aatgaaaaat caaaatcaac ttatagacgc
    32101 tttagcagta ggagtactag catcaaaaga aaattctcct gtactaatcg taggagaaca
    32161 attaagtgca acacaaaaga gtgtattttc gaataaaaat gctacctcta taactcaagt
    32221 tggtagtgga ggaaatgaaa atgcatttaa agaattaaaa gatttacagg caaatagtaa
    32281 caataagaga gtaatgtatg taactaatac agataaggta aatataagaa atgatgctac
    32341 aatagaagct tctgttatag gatatctaaa taatggtgat gaagtagaag ttttagatgt
    32401 gttaaaaact ggatgggtag aaataaaata caatgaaggt attggatatg ttagtgggtc
    32461 ttatttgaca aataataagc ctgataatag taatgaaaat ataaaaataa agtatgtaaa
    32521 agaaaaagat ggtctaaatg ttaggaaagg accaagtaca gaagatgaaa aaataggtca
    32581 cctttcatat ggaagcaaag tagaaacaat agaaatgttt gctactggat gggtaaaaat
    32641 aaagtataat ggtggatatg gttatgtaag taatgattac ttatctgata caccagttat
    32701 ttaattataa gtaacaataa aaaaactgct ttaatttgta aagcagtttt tttataaaaa
    32761 tttaagtcta ataactattt ctattttgat accttaatcc tgggatttat tattatggat
    32821 attatcaaca tacaaacact ccaaatccag tgtctaattc caaacttaga tattaataaa
    32881 ttcagtcctg ctatggtaaa taagcagtat ttaattacaa ttaaaagtgt atttatagaa
    32941 agccccttca tagaaagtat cctaaatcca ataatagaca ttctaagtcc tataaatgcc
    33001 aataatatac ctgcaatatc ctgaattaag taatagtatt caaatttcat attcaatcaa
    33061 ctcttctctg agcagtatca aatatttcta actcttcaat ttcatcatct gtgtatgtaa
    33121 gcatagtaaa accagttaca ccataaataa atgaaattat aggtgtaatc caacttaaga
    33181 aacaatatgg aataaattct agtgggctta caccaagagt ctgagcacag aaaacagcat
    33241 ttgaattcca tggtattaat ggaccaccaa gtgtagctgt atcttctata attctagata
    33301 gattttgtgg ttttaattta aattctttgt atattggaga cattagagtt ccgacaaata
    33361 cagaagtgaa catcattgat gaactaaatg catttgcaaa gtaacttact ataaaagtag
    33421 acccaaccaa tttagttctt gattttccta ttttagttat aagaggttga agcagtactt
    33481 ctaagaatcc agttttttgg agaataccag caataacgaa aactacaaat actagtaaaa
    33541 cggtttcagc catactcatt attccaccac gatttaatag tttgtcggca tagacaaatc
    33601 cagtatctat agtaaatcct gatagcatgt aatttaaaac atcacctatt ttttctcctt
    33661 cttgaaatac tgctataata agtcccatga tagctgaact tagtatagat ataatgggtg
    33721 gcttttgtag caataaaagt aataataaaa atattattgg aatcattgct actaaaccaa
    33781 tatgaaagtt tgaatttaat acatccttga tttgatttat ttgaacatag tctatagtat
    33841 tatttgaata cttaaatcca attactgtat acagaactat acatattacg tatgcaggtc
    33901 ctgtggtata aaacatatgc ttcatatgtg taattacatc tgtcttacaa actgctgcag
    33961 ctaagtttgt agaatctgat agaggtgaca tcttatctcc aaagaaagca ccagaaatga
    34021 ctgcaccagc tgttaaacca agaggaatac ccatactagt accaatactc atcattgcta
    34081 taccagaagt tccaagagtc ccccaagatg taccagtagc aacagaagtt aatgaacata
    34141 cgattaatgt tgtaagcaga aaatatttag gggttattat tgttagtcca ctatatacta
    34201 ctgttggtat tgtaccagca gctatccaag ctgctattag tacaccaaca gaaagtataa
    34261 ttaagtttga ttgaaaggca tctttaccaa cttcaaatcc aaaagcttct atttcatcat
    34321 tagtataacc aagtttcata gctgcaggaa ctactataag ccatgaaagt aaaaacattg
    34381 tagttataga agcattaaat acaactatac caactgatgt tagagctatt attgcaagca
    34441 ttactaacaa ggaatatcta aatgaaggta tttttctttc tgtattcatt ttcatagtgc
    34501 aaattctcct taaatatttt tagttaattg cattttttat tcttataaga gcttcttcaa
    34561 gcatacttct tggacaagct aagtttattc tttgataccc acttcctcca atgccaaagc
    34621 tgtttccttg atttagagca actttacctt tttgtacaag tatactttct agttcctcat
    34681 cacttaatcc aagtgcacta aagtctaccc ataataaata agtaccttct ggttttctaa
    34741 ctttaagttt tggcatattt tcatttatat attttatagc aaaatctata ttagattcta
    34801 aatattctaa aaatgattct agccaagatt caccattatt atatgaagct tcagttgcaa
    34861 ctaagctaaa gcaattattt ctctttatat caattctggt aaaggcatca tctaacaatt
    34921 tatagtcttt ttcatcaggt agtattacat atgatgattg aagaccagct atattaaaag
    34981 ttttagttgg agccatacaa gtaattgtat ttttttcaaa ttctttagaa atagatgcca
    35041 taggaatatg cttatgtttt tttaatataa tgtcactatg tatttcatca gatatgattt
    35101 ttacattatg cttaagacaa atatctccta gtttttttaa ttcatctttt gtccatactc
    35161 taccaactgg attatgagga ttacaaagta tgaataattt tacatcttta atcttgtttt
    35221 caatgtcttc ataatccatt atgtagtttc cattttctag tttttgtaat gggcttataa
    35281 ttagttctct attgttattt tttacaacac tattaaaagg gctgtaaact ggttcttgta
    35341 tcattatttt atcatttgct tttgtgagtt catttattaa aagacttata gctgggataa
    35401 cacctggact ataaattaac cactcacttt ttattttcca gttatgtctc ctatctagcc
    35461 agtttactat agattcattg taagaatctg gtcttgttgt gtagccataa atctcttgtt
    35521 ctagtctatt ttttaaggaa tcaattatac aaggtgcagc cttaaaatcc atgtcagcca
    35581 cccacatagg aagtaaatca ttagttccat actttttttc catttctgac catttagatg
    35641 aaaaattatt gcttctatca acaatctcat taaaattata attcattgta aatacctcca
    35701 gtaattttaa ttttatgtta ataatattaa gcaaacaacg tgccaatatt gataataaaa
    35761 aatatttatt cacaagttaa tatttaatat taagtaattt cagagcatag ataagataaa
    35821 aatattaatt atacttaaaa ctttgtggaa aaggttattt ctaataaatt tttaaatata
    35881 tgaaaatgta attaaatagg ttaaataggt ttaactgttt aacttgttag acctatttat
    35941 attttttaga aattctactc cttttgatgt tataattgaa cctccacgac caacaagtat
    36001 gtctacaagc ccaaagtttt gtagttctaa aagcatattt ctaatctgtt gttctgtcaa
    36061 aaatctattt tcctctaaag ctattttaca taagcttttt ctacctattc tttcttttaa
    36121 atcataagcc ttttttaaat tatccaatat aaatatgtat tcatctagtg accttttaaa
    36181 attatagtcg tatttcatga tgtttttgtc tttgccaatg ttgaattgat acttttttat
    36241 attatcactt actttattac aaacggttct actataattt gaatctatag tatctaatat
    36301 atattcaggt aaatcacata tttctataat atctttttcc aagtaacaga agtattctcc
    36361 taagtttctt aattctctta catttccttc ccatctatac attttaaaga tttcttttac
    36421 ttcctcactt agaataaaat tacatggaat atcatatttt aatgaaccaa aaatttcaaa
    36481 tatatcagca ggtctttccc taagtggatg tattttaagg ggaagaacat tcaacctaaa
    36541 atataaatct cttctaaaca tatttttaga tacaagttct tttaaatttc tattagtagc
    36601 tgcaattatt cttacatcaa tgtcaatgac attattagaa ccaatacgtc gtacttgttt
    36661 ttcttgtatg actctaagta atttagattg agaatttaaa tccatttctc caatttcgtc
    36721 taaaaatata gttccattgt tggctaattc aaataaacca attttcccac cttttttagc
    36781 accagtaaaa gccccttcat catagccaaa taattcactt tgcagtagat tttcttgaaa
    36841 agtactacaa tttactgcga caaaaggacc atcttttctc ctagaagcac tatgaatgga
    36901 ttgagcaaat aattctttac cagtaccact ttcaccaatt ataaggatag atgaatttga
    36961 ttgagccatt ttattagcaa ttttttttgt attaatagtt tgtatactag aacctaatat
    37021 gtcatcaaat gtgtatttac tgatattacc agagtttact agttgtgctc ttaatttagc
    37081 ttgctttttt tctaattgag aaaactttgt catctttagt ataaatccat caaatacatt
    37141 taattgtata tgtttaatct ctaaatttat atcaatatga tttattttaa tcaatttctc
    37201 aaaaaatgga gttttattgg tcaatatgct ttgaaaattg atgtctttta tgcaatcacc
    37261 aacaaatgag tcaatcattt catttgcatt tatagacaaa atttttctag ccatatgatt
    37321 atagaattga attattccat cgttatttgt gcatataatt ccatcatcaa ttatagatag
    37381 caacaaatca aattgtcttt caaacttatt tgcatctaac aataactcac ctgtactata
    37441 acttgtagga attatttttt ctacgtattt ttttattagg tcatctttta ttagatgttt
    37501 taatttggtt tttgtagcaa tttcaacaat acaacttaaa tctattattc tgtattttaa
    37561 atctataact tcacaatttt taaacttagg caagattttt tcgccaggag ttaggattac
    37621 agcatctgtg ggagtaaact caatctctgg atagcagggc aggatattta tattgtctat
    37681 tcctaatcta tgtattaaag aaattgtttc tattgccata tctttactta agttatatac
    37741 ataaataatt ttatcttttt ctaatttgga tatcatatca atactgttct tttcaaatgt
    37801 caacttagga acaatgattt gagcatcata gtgagataat tttactattt catcatattt
    37861 taaataagca gataggagta taagtttttc tttaaaaaac tttaaatttc cctcttcaaa
    37921 tgagtataaa tttatcttta gattatcacc taagaattgc cttatttgat tttcataaat
    37981 ttctccagcg tcttttttta aacttacaat agctaattcc atttgtttca ttttaacctc
    38041 tcatacaaat ttgacttatt ttagattaca taataattaa attagattaa ataatattat
    38101 ttaattatta ttataaattt attatagact acacattgaa gtaaaagaag tagctaaaat
    38161 tattcctttt atttttgttt tttgtatcta tttggtataa tagtattaga gcgtataata
    38221 atttaggcaa aattttttaa ggaagactag aggagaatat aaaatgaaaa aatgtcttta
    38281 ctgtaatagg gatataaagt caccaaataa taaattagct ataaaatatg atgacaatat
    38341 gaatatatat ccatgtcgtg cagaatgtaa ggaaaaaatt gaagaatata tagcaaaaaa
    38401 acctacatat aagtttataa atatattaga ggttctttta ggtgtgggcg gaatattctg
    38461 ctttttgagt aaatggacta ttgcagccca agttgtactt ggaattgatg cactggttat
    38521 atttttattc ccattggcag gatttaaaat gaatggaaag ttaagtatgg aacaaactaa
    38581 gaatcaaagt aggtctattg caatatcaat tttggcattt atagtaataa taactgtatt
    38641 atattttaaa caagttggta agtagagcat aattgtataa gacatcatta gagtatgagg
    38701 tgagtttatg gaagaaagaa aattagcacc aaacaatgag agggaagctc tcataaaaag
    38761 attaaaaaga atagaaggtc aagttaaggg tatacaaaag atggtggaac aagaacgtta
    38821 ttgtgttgat atattggttc aaatatctgc tataaggtct gctataaata gagtaggcac
    38881 aattatctta gagaatcata taaaaggatg tgtagcagaa agtattaaac atgatgatgc
    38941 tgataaaact gaagagatga taaaagagct tatggatact ataaataaat ttacaaaata
    39001 aggaggcggt tagttatgaa tcaacaagga tttattatgg aaattgttga tgatagaact
    39061 gcaaagttaa aaatgcaaag acattcagct tgtgctgctt gtggaaaatg tgctactaca
    39121 aattcagcag agtcaaaaga aatattagta gaagtagaca acacaattgg tgcaaaagtt
    39181 ggtgaccatg tagaagtgag tatggataat atgaatgtat taaaagcagc tgtaatggct
    39241 tatataatac ctcttatagc acttcttgta ggaacaatag ggacttatta tatattgggg
    39301 gcaattggaa tgacaactgg agttgaagcc ataagtggat tagttggaat ttgtcttaca
    39361 ataatctgtt atttatactt aaagaagaat gacaaaaaat ttagagacag tagagaattt
    39421 ataccagtaa taacaagaat attaattgac ctttaagata attataatta aaaaatagca
    39481 atgtactttt taaataaata ctcaatacgt atttgtagag tttaagtaca ttgctatttt
    39541 tatattttta ttttgatttt ctgtaaggaa taaagttttt tctgattttt aaaagattca
    39601 atgttcttac aaaagaagtt acaactaata caccaagtgc tattgcagca cttagaaata
    39661 gcgcatctgt accttttgac atagccaaag aataattttt ctgaatcaaa gacaacattg
    39721 tattatatag cccaattcct ggtattagag gaagaatacc tggaattacg aacacaatag
    39781 ctggttgctt tagttttctt gctaaagtct cactgcacgc tgagaccaaa gcagcagcga
    39841 taaaacctgc aaaaactgca tttgtagtaa aattaaataa ataaacatat acaatccaac
    39901 caattccgcc agttactcca gctggaagaa gtagatatag tggagcatta aagaaaacag
    39961 caaatccagc agttgcaaca cctgaaaata aaaaatgcaa aatcatagac atatcagtca
    40021 ttagaaagga cctcctattc tataccatgt atcaaggaca aaaccaactc cagaagcaat
    40081 tgcaataata atcatagcag catcaaaagc acgagaaatt cctgatatta aattccctga
    40141 tattaaatct ctaatagctt ttataaaagc aactcctggg agtagtggca ttatagcgcc
    40201 gactataagc attttagggt catctaaaat gcctatttca actagtagaa ctcctgaaag
    40261 tgcaattaaa aaagaagata ctaaacagga aaatgcagat attgcactta tcttcatcgt
    40321 tttatcataa gtaattgcag caaagattgc tattataaac gtaagtataa aatttaatac
    40381 ataattccct ccaagcaaac aagcaaaaca agcagatgca attcctgtac aagagtaaaa
    40441 taaccataaa ggataaggtt ttacatcttg gatttcataa agacgtgcaa tggcattatc
    40501 aatatcatac tctttgtcac taacaaattc tcgagaaaaa ctgtttaata aagaaatctt
    40561 atttaagttt atacctcttg attgaatcgt tttcataaac gaaaagccat caaatttctc
    40621 atctgaaata attattactg taggagttgt aaaaatattt acatgataaa accctcttga
    40681 cctgcatatt ctaaggacac tgtcttcaac cctagatgtt tcagctccat tttttatcat
    40741 cagttcccct acaaatagag ctagttttag aatatttttc ttatattcaa gttcctcatt
    40801 ttgattcata aatacacctc caaattaaaa aacgtaatat tgaaattata tcaaattttt
    40861 aagtaatatt ccttaatatc tatacaaata tattatcttt tttttgtttc aaaatagtca
    40921 catttaaatt atatccaatt aaaagaatta gacaatatta tttattatat tttaacttaa
    40981 aaataaagaa agtaactatg ttaaatatgg aaaaatggca aaacacttga ctattaattg
    41041 gtaaaggact ataataataa attatcatat tgataaaaac gaaaattatg aaatgtctgt
    41101 aaaaataaaa tttaaataat aactaggagg agtaatatgt ttgagaactt gaaaaaagcg
    41161 gaccctgaga tttatgaaag tatgaaaaga gagttaaaaa gacaacaaag aaatattgaa
    41221 ttaatagcat cagaaaacat agtatcagtt ccagtaatgg aaactatggg aagtcatctt
    41281 acaaataagt atgcagaagg ttactcaggc aaaagatatt atggtggatg tgaatacata
    41341 gatgaagttg aaactcttgc aatagataga atcaaaaaaa tatttggagc agaacatgct
    41401 aatgttcaac ctcactctgg agcaaatgca aatattggtg tatattttgc tatgttaaaa
    41461 ccaggtgatg ttgttatggg aatgaattta tctcaaggtg gacatttaac tcatggtgct
    41521 ccagttaata tttctggtca atattataaa ttttatgaat atggtataga taaagacagt
    41581 ggacttatag attttgatga agttagaaag atagcacatg aagtaaaacc taaaatgata
    41641 gttgcaggag caagtgcata tcctagagaa atagatttta aaaagtttag agagatagct
    41701 gatgaggttg gagcattgct tatggtagat atggctcata tagcaggtct tgtggctgct
    41761 ggtcttcacc aaaatccatg tgaagtggct gattttgtta caacaacaac tcacaaaact
    41821 ttaagaggac ctcgaggggg tgttattctt tgtaaagaaa aatatgctaa agacatagac
    41881 aaagcaatat tccctggtat tcaaggtgga cctcttgaac atataattgc ttctaaggca
    41941 gtttgcttta aagaagcttt aagtgatgag tttaaagaat atcaggtaca agttgctaaa
    42001 aatgcaaaag ccttagctga agaacttatt aaaagagatt ttaaattgat ttctggaggt
    42061 acagataatc atttaatact attagatttg actaataaaa atataactgg taaagcagca
    42121 gaaaagagat tggatgatgc ttatataaca gctaataaaa atacaattcc atttgaccca
    42181 aatggtgctc ttattacaag tggaataaga cttggtactc cagctgtaac tactagaggt
    42241 atgaaagaag aagatatggc aataatcgct gaggctatag acctatgttt aacttatgat
    42301 gaagaatcta aggctagaac attggttgtt ggtttaactg aaaaatatcc tttatatgaa
    42361 gaatataata ttatggatta attataaaga acaactaaat aaaatacatt taaataatta
    42421 caatgattgt gtatgtattt gaatatagtt agatataaaa aaggtgtctc aaaatgaact
    42481 ttttagttta tgaggcactt ttttgtatgg aatcgaacat atttgtgtta tttaaataat
    42541 aaaaaatatg gttatctcta tttttagatg gtctctttgt attttttaat taaaacttta
    42601 agatttctta agaattatac taggtttttc taaagattta aagtctatac ttataagtat
    42661 agtaatcata tgaaaagaaa agctttaacg aggagggaat cttatgaagg tattaattct
    42721 tacaggaaaa tttggtatgg gtcattactc agcatcaaat tctttaagtg aagatataaa
    42781 agcaaaattt gataattcag aaataataat taaagatata tttgagtaca ttatgcctaa
    42841 ctattcagat aaaatgtaca agactttttc tattcttgta aatcggggaa gtagtcttta
    42901 taatttattt tataaatgtg ctgaaaatgg aaagaaagat ataaaattta ctttttcaga
    42961 ttatttttta aataaattag atacattact tcatgaagta caaccaacag tagttatttc
    43021 aacttttcca ttttgttctc aattagtatc aagatataag gaaaaatata actcaaatct
    43081 tcctttaata acatgtataa ctgatataag tagtcactca gaatggatta gtaaaaatac
    43141 agactgttat ttagtagcta gtaaatctac taaggaagaa cttgttttta aaggaataga
    43201 tgaatctaag attaaagtta atggtattcc agtaaaaaaa gaatttaaaa gaatagaaca
    43261 tgtaaatcat tcaactaaaa aaaatattct tataatgggt ggaggattag gattactgcc
    43321 taaatcagaa caattttaca aagaattaaa tagtttagaa ggagtaaaaa ctactgtaat
    43381 aactggtaat aataaaaaaa tgtactataa actatatggt agatatgaaa atatagaggt
    43441 agtaggttac accaatgaag tatataaata tatgaaagat tctgacctta ttatttctaa
    43501 accaggtgga ataacactat ttgaaacaat ttattcagaa cttccaatat tggcatttaa
    43561 tccattttta caacaagaga tagataatgc tagttttata ttaaataatg aaattgggag
    43621 aatacttggt aaaaataaaa aatactatgt agatgagata aaagatttaa tttatgatga
    43681 tgctactctt aaagaaatga gcagtaacat gaaagaatta aaaaaacaat ttgataataa
    43741 taccttagag aatattttat tttcacttga tgaacaagga gcgtgtagag aatgtatgta
    43801 gtaggtttaa ttatcgttgt tgcattgatt tttttagtcc attcaattat acctacatac
    43861 tataataaac tattaaataa agaggtatta aaaaatatgg ctggagaaaa tgaaattgca
    43921 cttacatttg atgatggtcc agataagaga tatacagaaa aattactaga tgtgttaaaa
    43981 gaaaatgata tacaagctat gttttttgta gtagcaaaga atgctgaaaa agagcctgaa
    44041 attataaaaa gaatgttgag agaaaatcat atagttggtt tacattcatt ggaacacaga
    44101 aatgcatggc tttatagtta tagttatgtt aaaaaagatt ttattgaaag tacaaatata
    44161 atgaaaaatt taggtgtaga tgtaaactac tatcgtccac catggggtca tactaatata
    44221 ttttcaaatt catttgttaa aaaatataat ctaaaaatga ctttgtggga tgtaatggca
    44281 gaagattggg agaaagatag tacagtagac attattataa acaagttaat gagtagaaca
    44341 aaagaaaatt ctataatttg tttacatgat gcaggtgaaa attcaggtgg tgcagtaggt
    44401 gcacctgagc gtactattga agctttaaag atagctattc caaaacttaa agccagtggt
    44461 ttaaagttcg taacaccaga aaggatgtag ttatgataag taaaactgaa aagaaaaata
    44521 aatgcctagg tagtgtagct tttttagttt tactaatggg cataacagga tattttgttt
    44581 ttagagggca gtcagttgaa tcattgataa aatcattaaa aggtgcaagc cctatgttta
    44641 tactaattgg atttgcaatg atgtttatat atgttgcctg tgaaggtata aatatatact
    44701 taggtatgaa agctttaaac caaaagacta ctcttttaaa atgtatggga tatgctttta
    44761 ttggatttta ttttagttct attacacctt cagcatcagg tggtcaacca gcacaagttt
    44821 attatatgaa aaaagacgat ataaatatat catattcttc acttatacta ttagtcattg
    44881 ttgttattca ccaagtagtt atactggcat atagtggaat aatgttcatt atggaacgtg
    44941 agtttatatt aaataatgta agtggtatga acattttact aatatatggt gtaataacaa
    45001 atgttgctct tgtcattgga gtaattgcaa ttatattttc aaaaaaactt gtaaacaatt
    45061 ttataatatc aataacaaat ttattaggta agttaagaat aataaaagat gttgaaagtt
    45121 caagaaaagt tataatatct caaattgaag agtatgttaa aggtgctcaa tatataaagc
    45181 agaatccaaa acttgtagtc caaattttag tcataactat tgtacaaata acagctatgt
    45241 ttttagttcc tttctttgta tacaaagctt ttcatctatc aacatatact gtatttgaga
    45301 tattagcgat acaatccttg cttaatattg ctgtttcttc attaccattg ccaggggctg
    45361 ttggagcttc tgaaaatagt tttatgacat tatttaagat atttttccct ggtcacttat
    45421 tagttccggc aatgttactt agtaggggaa taagttttta tgcatttgta gctataagtg
    45481 gattgatatg tatagtagta catgtaaaat cttctgaaaa agtaaaagca gtgaaaaaag
    45541 ttgcttatgt aagataatat tatatagatt atttttatta atatgtcaat ttgtgtgtat
    45601 attttaatta agctttaaac atatttacag gagtagaaac tattaaaacg tgtgacattg
    45661 ctaagctttt gctaataaag tataatattt tatatagttt gaaatattta agaaatatag
    45721 caaaaaaagg agcttggtga tgaataaaga gattccaaaa aaaattttag tagctgatga
    45781 taatcctgag attagggaaa tcgtagaaat acttttaact ggtgaaggtt atgaagttat
    45841 tatggcaacg aatggagaag aagctgtaaa cttagtagat agtacgattg atttgattat
    45901 tttggatgtt gtaatgcctg taaaaacagg atttgttgca tgtaatgaaa ttagagaaaa
    45961 aacgacagca ccaatattat ttttaactgc aaaaactcaa gactctgata aagttattgg
    46021 attttcagca ggaggagatg actatttatc aaagcctttt tcatattctg aactaatttc
    46081 aagagttaag tctctactta gacgttatta tatataccag ggaaaggaaa aggaaagaga
    46141 gccaaatata ttaaaaacaa aagagttatg tgtcaattta gatactcaag atgttacact
    46201 aaatggagaa cctgtgtttt tgacaactat agaatatagt atattaattc ttatgttgaa
    46261 aaatagaaaa aaagtttttt cgtctgaaaa tttatatgaa actatttggg atgagcagta
    46321 tttttataca gcaaataata caataatggt tcatattaga aatttaagaa aaaagttaga
    46381 aaaagaccaa aaaaatccac aatatataaa aaccgcatgg ggaaaggggt attatattga
    46441 ttaacaaaat taagccatct aagttgggag ttatactatt gatatatgta gtaatctcag
    46501 ctgcagtggc tttcatttta aatataccat tttactctgc tgttgaatct atagtaaaag
    46561 atgtatcaga agggaaagta tattttaaaa gagaagtaaa tcaacttatg gataattttc
    46621 aaacttatgt gaataacaat ggtataagag cagatgatgg agatgatata gcaaaatgga
    46681 atagtgataa ttggtttgtt tctatgaaga tatataaagg aaataaggtt ttttatgata
    46741 cattatacta tcctaatgaa gtacctgata agagtgagga aaatgagttt tatagcagtc
    46801 ccatggctag aaactatgag atacaatttt ctgatattaa agctaatata gttgtagtag
    46861 ctttatttag atttagattt caaaatttta tagaagcaat ttctattaca tttatggcac
    46921 ttacatttat tataacattt ttactgttgt ttagtagaaa gataaagtac ctaaggaaaa
    46981 tagaaatggg tataaagata gtagagagtg gcagtttaaa gtatagaata ccagtaaaag
    47041 gtaatgatga attatcatca cttgcatcta gtattaatga gatgagtcat acattggaga
    47101 atcaacttat aaaagaaagg gagatgaaga ataaaaataa agatatagta acttcaatat
    47161 cacatgatgt tagaactcca ttaacgtcag taatttgtta tttagatttg attaaagacc
    47221 ataaatacaa tagtcctgag caattggaac aatacataaa aaatgtaagg tctaaagcat
    47281 atcaaataaa agatttaaca gatgaccttt ttacgcattt tgttaattct ggagaggaag
    47341 tttcaaaagg gtatgaaaaa ataaatgcta atgaatttat ttttcaatta cttttagata
    47401 gttcatatac attggaggag aaaggatttc atataacaat agaaaatgaa ctttataacc
    47461 aatatcatat ttatgtagat gttacacaat ttagaaggat atttgataat ttatgttcta
    47521 atataataaa atatgctagg aaagataagc ctatagtatt tttaattaaa gtagaggatt
    47581 ctaaattact aattatacaa aaaaatagag taagtaattt ttctaagaat gtagaaagtt
    47641 ttggaattgg tataaagaat tgtgagaaaa tagttgcata tcataatgga agcataaatg
    47701 taaattcaga tgataaagaa tttgctattg aaatatctat tccagcaaaa gaatcataaa
    47761 aatttaaatt atatattgtg taattgctat tatatattgt gtaattgctt atgtaaaatt
    47821 ctatgaagca ggaagcatgt gactttagtt atgggatgtt caatattgtg tacctctagg
    47881 caagtaacaa gtttacttac aagaccatat aatattatta tcttaaaaaa aggggacata
    47941 ataatatggt tttgacagga gcacattata tttacattct atttatggta attatattaa
    48001 ttactatgat tatgaaaaag gatacaatag taccatgtat attaggtgtt ttttttatgg
    48061 ggttgttctt tgaaaaaaac atttttggtg ctataacagc agtgtttaac tcttttatta
    48121 tatctttaaa tgagttgggt ccaattatct tgattatagc tattatggtt gcattatcta
    48181 aagccctaga agccaataat gctatacagt atatggtgag accattttcg agagttataa
    48241 aaaattctaa tacagcattt tttgtaactg gatttgttat gttagttctt tcttggtttt
    48301 tctggccaac tccagctgtt gccttagttg gagctgtatt tttacctgtt gctatgagag
    48361 ctgggctacc agcaattggt gttgcagtag cattaaattt atttggtcat ggtcttgcct
    48421 tgtctacaga ctttgttatt caaggagctc caagtataac agctggtgca gcaggtgttg
    48481 cagtatcata tgttataaat gatggtatga ttttgttttg ggtgatggga atcgtaacca
    48541 tatctatggc attttataca ttaaaaagag atattaacaa aggaatgttt agagaagaac
    48601 taaaaggttt tgaaagtgaa gaagtagaag agttcaatgg aaaatctaaa atagcaacta
    48661 ttttagtagc tctgggattt cttgctgata taattgctat gtatatattt gacctaaaag
    48721 gaggagatgc atcagctctt ttgggtggaa cagcagtatt tttaataata attataaatg
    48781 ttataaattt tggcaaagat agtcttgaaa atgtatgtga gaatataatt gatggttttg
    48841 tgtttgggat aaaaatattt ggagcaatta taccaatagc agcatttttc tatatgggtg
    48901 aagttgcacc attgacaggt gtatttggaa aagtattagc accaggttca caaggtttat
    48961 tatcagatat aggcatagct ctttctcaaa caataccact taataaattt gccgtatcag
    49021 gtatagaaac tgtagtggga gcaataactg ggcttgatgg ttctggattt tctgggattt
    49081 cattagttgg ttcacttgcc tctgtatttg gaactgctat aaatgcaagt gttggtgcac
    49141 tagctgcatt aggacaaatc agtggtatat gggtaggtgg aggctgtcta gttccttggg
    49201 gtcttatttc agcagcggca atttgtggag ttagtccaat agaattggca aagcgaaact
    49261 ttgtcccagt tataaccgga ttggttgtaa caaccatagt agcaatgttt attatttaat
    49321 aaatcgaata aatctttaat tgtataaatt aaaaatagat gtgtagctat aatttattat
    49381 aattgtttta ctaattctaa gccatacatc tatttttatt gatattttta ttagtattct
    49441 ttaataaaat aatatttttc attatactat acataacatc taaatataac atctaaaata
    49501 ctgttatcta tatttaatat cttgccaaat tttttgatgt tttattgccc tgtcccacca
    49561 acatatataa gctatcacaa gtttttacct atactatcac caaacaaaaa ttctaatttt
    49621 aatttattat tttataacct atattatatt aactatatta gtttgtagac tttagatgta
    49681 attataaata ttaatactcc aagagttcaa attcatatcc tagttttctt gcatttgata
    49741 taaaatcatt taaaatttct gtactagttt tggaaactgc atgtagtaac aagatagaac
    49801 catcatgtag attatccatt attttttgcg ttgcttcttc atgtgatggt tgtttatcag
    49861 tatcccagtc tctgtatgca aaactccaaa atacagtctt gtatcctaaa tttttagtca
    49921 ttgccaagct tttttctgag tattttccca taggaggtct aaaaaattta accatatctt
    49981 tcccagttac atctttatat aacttttcaa catcatataa ttcgtcatta aagtttttta
    50041 gattgcttgt ttttgttggc atagatggat gggttttact atgatttcca actatatgtc
    50101 cctcagaaac cattcttttt actaaatctt tattttcttt tatatatgga gctgtaacaa
    50161 aaaaaactgc tttaacctga ttttgtttta gagtgtcgag tatttttgta gtgtatccat
    50221 tttcataacc ttcatcaaat gtaagatata gtgttttttg accatctttt gtaggtccat
    50281 tgtatagggc atcatagtca gaaaatttaa attcaatgtc cgtatttact tctggtgttt
    50341 tatgcttatt gtttggtata taaaaccaat caagagtagt gttatctaaa gaagatacat
    50401 ctaatttatt attatcatta ttagtagtgg cttttgatgg tttatctgtt ccgtctgaaa
    50461 ctattacatt ggaagtatct ttaccactat ctattttttc cttatcttct tgtaactgtg
    50521 tttccttatt ttgattttcg ttttgattgt tttgtgaatt tgaacatcca acaataaaaa
    50581 aaatagaaat agaaagtagt gttaaataat gcaatacttt tctaaacatt ttgaagctcc
    50641 tttctaaatt aataataatt gcatataata ataattatat gattaattac aattgcatat
    50701 agtattatta taattggaaa ttactattaa taatagttat atctttaaaa ataaggtcac
    50761 aatagtatga caaagggtga ataatcaata aatttaaaaa aaaatgaaaa aaatagttga
    50821 ccatattatg agaagatgtt attataataa atgtgctcaa caagaagtaa caaaataaca
    50881 agcacaaaga agttaattga at
//
LOCUS       DAYAOO010000021        50430 bp    DNA     linear   BCT 12-OCT-2024
DEFINITION  TPA_asm: Clostridioides difficile isolate ST8-SSI-h139-18
            SAMN40601845-rid21577343.denovo.021, whole genome shotgun sequence.
ACCESSION   DAYAOO010000021 DAYAOO010000000
VERSION     DAYAOO010000021.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN40601845
            Sequence Read Archive: SRR28438827
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 50430)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 50430)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-MAY-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-MAY-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002157583.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002157583.1
            Genome Coverage       :: 163x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/11/2024 16:19:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 4,038
            CDSs (total)                      :: 3,963
            Genes (coding)                    :: 3,930
            CDSs (with protein)               :: 3,930
            Genes (RNA)                       :: 75
            rRNAs                             :: 6, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 60
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 33
            CDSs (without protein)            :: 33
            Pseudo Genes (ambiguous residues) :: 0 of 33
            Pseudo Genes (frameshifted)       :: 7 of 33
            Pseudo Genes (incomplete)         :: 25 of 33
            Pseudo Genes (internal stop)      :: 11 of 33
            Pseudo Genes (multiple problems)  :: 8 of 33
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..50430
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN40601845-rid21577343.denovo.021"
                     /isolate="ST8-SSI-h139-18"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Denmark"
                     /collection_date="2018"
                     /collected_by="Statens Serum Institute"
     gene            191..1384
                     /locus_tag="ACGI5H_001350"
     CDS             191..1384
                     /locus_tag="ACGI5H_001350"
                     /EC_number="4.3.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422058.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003941 - L-serine ammonia-lyase activity
                     [Evidence IEA];
                     GO_process: GO:0006094 - gluconeogenesis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="L-serine ammonia-lyase"
                     /protein_id="HFG9697061.1"
                     /translation="MDTLKELFKIGSGPSSSHTMGPQRAAERFKNENPDAESFRAILY
                     GSLAATGKGHLTDYIIEKTIAPKKVEIVWEEDIIKDFHPNGMKFEALDKDKNVTAEWT
                     VYSVGGGTIAEEGQRNSKSNSIYHLDTMDEIVKWCKENNKTLVDFVLECEPKDIKDYI
                     KTIKDAMRKSIDDGLSTDEIIPGKLLLKRRASTFYNAYKKDKSFSTLVYAYALAASEQ
                     NASGNIIVTAPTCGSAGVIPGIFFAMQDFYNYDDEKIIEALLVAGIIGNIIKTNASIS
                     GAEVGCQGEVGAACSMAAAAVAYLKGGTIDHIEYAAEIALEHHLGMTCDPVYGYVQIP
                     CIERNAMAAQRAYDAANYALLTDGSHSVSLDQVVETMKETGIDMMDKYKETAKGGLAK
                     HFFSC"
     gene            1590..2708
                     /locus_tag="ACGI5H_001351"
     CDS             1590..2708
                     /locus_tag="ACGI5H_001351"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438795.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetyldiaminopimelate deacetylase"
                     /protein_id="HFG9697062.1"
                     /translation="MREASYLQEQLYKHRKSLNPIAEIGRKEYKTSKYIRDYLDKLGI
                     EYEVYLETGIVGVIEGKRPKKDIAFRADIDGLHSEEGVKHLCGHDGHATILLGLIEYL
                     NDNKEDLNDNIVFIFQPAEEGPGGAKALIDEGVLRKYNIDEIYGLHIYPELPEGYVGT
                     REGYFMAQIGDIDIEIVSKSGHGAMPQNGIDGIVIASNFVSSLQTIVSRNISPIDNAV
                     LTIGRIEGGARRNIIAENIKMEGTMRCFSPEVYEKMKLRVRELARGFELAYNCKVNIN
                     IIDDYIAVKNDKDLYQEFVEAIGSDTVVELEPLMISEDFSYYQKEVPGLFFMLGSRNE
                     EKGFVNGLHNINFNFDEKICVNALNVYSKLLKYKEAID"
     gene            2839..3084
                     /locus_tag="ACGI5H_001352"
     CDS             2839..3084
                     /locus_tag="ACGI5H_001352"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009906336.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003690 - double-stranded DNA binding
                     [Evidence IEA];
                     GO_process: GO:0006265 - DNA topological change [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="small, acid-soluble spore protein, alpha/beta
                     type"
                     /protein_id="HFG9697063.1"
                     /translation="MKEKVQREKKITNGKNTKILTNDDIMKYEIASELGLMDKVGERG
                     WAGLTAKEAGRIGGMLTSRKKRLKKIVEEQNKKDESI"
     gene            3071..3817
                     /locus_tag="ACGI5H_001353"
     CDS             3071..3817
                     /locus_tag="ACGI5H_001353"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HFG9697064.1"
                     /translation="MSQYSDFAFVYDELMNEVDYNGWVKYIEDIIDSEGVKVKNILEL
                     ACGTGNLTIPLTKKNYDIAGIDISDEMLSVAREKAEKEGVELVLLQQDISELDFEISD
                     LDCVLCACDGFNYITYDDDLENVFSKTYELLKKDGIFIFDISSFYKLANILGNNMYGE
                     NREDIAYMWQNYFDEEENLIEMELTFFIKDECGKFERFEEIHQQRAYTEDEIVDMLEK
                     SGFKDIKYYGDFTFDKPSEESQRIFFVCKK"
     gene            4102..4977
                     /gene="hslO"
                     /locus_tag="ACGI5H_001354"
     CDS             4102..4977
                     /gene="hslO"
                     /locus_tag="ACGI5H_001354"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903657.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0051082 - unfolded protein binding
                     [Evidence IEA];
                     GO_process: GO:0006457 - protein folding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Hsp33 family molecular chaperone HslO"
                     /protein_id="HFG9697065.1"
                     /translation="MRDYVLRATSGNGQVRAFVATTRNTVEEARRLHETTKVATAALG
                     RTLTATSIMGLMMKNDSDKLTVIIKGGGPIGTIIATSDSKGMVKGYVGNPQVEVEDYP
                     NGKLNVAAAVGTEGVVKVIKDLGLREPYNGTYPLVSGEIAEDFTYYFAVSEQTPSVVA
                     LGVLTKEDEVEFAGGFIVQLMPDAEEETIAKLEENVAKLPSITNMLKEGKSPEDILNI
                     VLDGLEPKILDTCEVGFMCECSKERVKTALVAIGKKSLAQIIEEDKKAEVGCQFCNKK
                     YMYSEEELLEILKEM"
     gene            5368..6168
                     /locus_tag="ACGI5H_001355"
     CDS             5368..6168
                     /locus_tag="ACGI5H_001355"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903655.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PIG-L family deacetylase"
                     /protein_id="HFG9697066.1"
                     /translation="MESKTKYIGISILILLMIFLIAKNFNGKLEIPIPESNSRKFKSA
                     AVFYPQHQDDEVLWGGSAIVDAIKQCGVDNVYVVLVSDGSGVNVFKANTKFRNLTRKQ
                     KEELRNNEFKSALRELGVKPQNVIILADIDKKEGTHYELMEKTILDFEHKFKGNVTHI
                     AHHYKYDDHIMHRKNGEVLKKLKREGKIKDDLYFVKPKYVKYIPRNERAIYKAMDFDD
                     YNKVKSACYEYKVVNSKRKMYGIGYISAHSYFEHLLNDPELTSVLSED"
     gene            6696..8936
                     /locus_tag="ACGI5H_001356"
     CDS             6696..8936
                     /locus_tag="ACGI5H_001356"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728840.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HFG9697067.1"
                     /translation="MNNEFIILKGCKENNLNNISLKIPKRKITIFTGVSGSGKSSIVF
                     ETIAKESQRQLNERFSTFVRSFLPKYGEVKADCIENLSTPIIIDQSRLGGNSRSTLGT
                     ITDVNSFLRALYSRFGSEYIGNANMFSFNNIDGMCPHCHGLGKKLVPNMNQILDMNKS
                     LNEGAILLSGFGVGSWHWNIFAESGFFDINKRICDYSEVELEKFLHGKAEKIKIENAG
                     QTNMTYEGLMVKFNRLYLSREGEISEATKKKLSKLLIEDRCPICDGRRLNERVYRSLI
                     NGYNIADLTSMQIDELAEVIKSIDEPEAQPLIKGIIEKLNSIIDIGLGYLTLDRETSS
                     LSGGESQRIKMVKYLNSNLVDLMYIFDEPSVGLHPKDVYKLNNLLKKLRDKGNTIIVV
                     EHDPDVIKIADHIVDVGPKAGKYGGEVVYEGSYENLLTSGTLTGNALSKFLPIKESVR
                     EHSGYLEVKNCNKNNLKNVSIKIPKGVLTLVTGVAGAGKSTLIKDEFLKQNPSAVLID
                     QSPVSANSRSSLATYSGIMNNIRSIFSKTNGVNASLFSSNSEGACDNCKGSGIVEMNL
                     AFMESIKSTCNICEGKKFKKEVLEYRFQGKNIIEVLEMSVLEAIEFFNLKQIKTKLQC
                     IEKMGIGYLTLGQTLDTLSGGECQRLKLASELNKESSVYILDEPTTGLHMADIENFIS
                     IIEEIVDNGNTVIIIEHNIDVIKRADWIIELGPEGGTKGGRVIFEGIPKQLCNNKISL
                     TAKYIV"
     gene            9350..10885
                     /locus_tag="ACGI5H_001357"
     CDS             9350..10885
                     /locus_tag="ACGI5H_001357"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422046.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0043190 - ATP-binding cassette (ABC)
                     transporter complex [Evidence IEA];
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycine betaine ABC transporter
                     substrate-binding protein"
                     /protein_id="HFG9697068.1"
                     /translation="MINDILTLLSERSDFFIKLSIEHLMISIISIIIAIVLGGIIGII
                     VSEFHNSSKPILGTINFLYTIPSISMLGFLIPFSGIGNTTAVIALTIYALLPMVRNTY
                     TGITNVDKNILEAARGMGSTDFQILYKIKLPLALPVIMSGIRNMVIMTIALAGIASFI
                     GAGGLGVAIYRGITTNNTIMTITGSILIALLALIFDFILGLVEKFFQRKRKKKNRKKV
                     FAILGSLILIVIIFTSYLFNPSKTQTIHIATKPMTEQYILGEMLDILIEKNTGLNVEI
                     TQGVGGGTSNIQPAMENGEFDIYPEYTGTGWNMVLKKNELYTESMFSKLQSEYKTKLK
                     MQWTGMYGFSNSYALAVRKEVADKYNLKNITDLKDVSSKLTFGAEYDFYEREDGYTPL
                     CNTYGLNFKDTVDLDIGLKYQAINEGKIDVMPIFTTDGQYSVSDVVVLKDDKNFYPSY
                     QCGNVVRLEVLEENPELSKVFKMVGDILTDKEMAKMNYDVENNNLEPREVAREFLNKK
                     GLL"
     gene            10901..11662
                     /locus_tag="ACGI5H_001358"
     CDS             10901..11662
                     /locus_tag="ACGI5H_001358"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HFG9697069.1"
                     /translation="MTPIIQFKNIKKQYNDKTIIDNLNLDIEKGEFLTVIGSSGSGKT
                     TLLKMINGLILPDGGNILINQTDIKNEDLIKLRRRIGYCVQGSVLFPHMTVEENISYV
                     PNLLSKKNKLEVKSAVNKWMEIVGLPNDMKVRYPSELSGGQQQRVGIARALASSPEIL
                     LMDEPFGAVDEITRKQLQKEIKEIHKKTGVTIIFITHDIYEALILGTKTLVLNHGVVQ
                     QYDTPENILNTPANQFVDQLLNIRKSIIDDDNLKE"
     gene            12000..12869
                     /locus_tag="ACGI5H_001359"
     CDS             12000..12869
                     /locus_tag="ACGI5H_001359"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438778.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_function: GO:0043565 - sequence-specific DNA binding
                     [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HFG9697070.1"
                     /translation="MDNNLITIEKTLDYIEKHLLDEMLDLNVISKEIGYSKYHLHRMF
                     TSVVGFSVHNYIQRRRLTEAARMLIFTEKPIIEIALISGYDTQRSFSRGFKKMFKRSP
                     NFFRRHQDFLPLQLKFDIHNRKKLRGDMVLDVKKVNCADINIVGYSGKVRKGFHIIGK
                     CWRDLHKNKEMIENKVDLGFLIGVSDYSNFKEIENTPTFTYIAGAQVATFGKLPNGME
                     KFVLPKSNYIVFTFIGKNEDSMQNVVEYIYQEWFPNSSCQFNENNLYDFVKYGEKTDE
                     NGLSEIQFWVPII"
     gene            13198..13449
                     /locus_tag="ACGI5H_001360"
     CDS             13198..13449
                     /locus_tag="ACGI5H_001360"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422043.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3781 domain-containing protein"
                     /protein_id="HFG9697071.1"
                     /translation="MNVENELLKNLDRLHTTELGVVRIKKNLSLETNDVVNWCKTKIE
                     SPNAIINRKGKNWYISVYDCIITVNAHSYTIITAHKEKK"
     gene            13561..14340
                     /locus_tag="ACGI5H_001361"
     CDS             13561..14340
                     /locus_tag="ACGI5H_001361"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891659.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HFG9697072.1"
                     /translation="MNDTVKEKLAESLTSDTTDILPYLPYLLQDFWELGSSPEQMLQL
                     FRKHIPFNEDTKVLDLACGKGAVSVKLAKELNIHIKGIDLIPEFINYARRKAIEYKVD
                     ALCDFEMNDANSSVKIEHDYDCVIFGAVGDILGNYKETISKLLPTIKSKGFILIDDAY
                     VVDKSTNEQLNFERVYPTYNEWCILFKELGLKLIECIPCLELENDVEEEMNWIITRAN
                     ELIKKYPSQKDMFEQYVISQKNEYTDLQQDLVGATWILQKE"
     gene            complement(14475..15125)
                     /locus_tag="ACGI5H_001362"
     CDS             complement(14475..15125)
                     /locus_tag="ACGI5H_001362"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438773.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9697073.1"
                     /translation="MNIVMINGSPKVNKNNSQYFLSELKQLIQNDNKVFTFKVDSTSK
                     YPDALNAILNCDRLIIASPLYVDGIPSHLLHFLEKCEKFLKTQNKKPIPVYAIVNCGF
                     NEGEHNHLAIQMIEHWCKKINFTWVQGIGIGAGEMFGSLESVPLGKGPKKDLGIALKE
                     LSKNILSDNIHIDDSNKSTIFISPNFPRFLYKLMGNHQWNTQAKSNGLTKSDILKK"
     gene            complement(15122..15625)
                     /locus_tag="ACGI5H_001363"
     CDS             complement(15122..15625)
                     /locus_tag="ACGI5H_001363"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861880.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flavodoxin family protein"
                     /protein_id="HFG9697074.1"
                     /translation="MRLLIHDLTDKELEKLLPKLDDNIKILPNTKEIHKCIGCFGCWI
                     KTPSECVVKDYYSNMGKLINDSDGIIIISRCCYGGFSPFVKNVLDKSINYILPYFVIK
                     DNMMRHKSRYDKQINLKAIFYGDCITEAEKETATKLVNGNAINFNIKEHSVCFYENIQ
                     DIRGESI"
     gene            complement(15674..16189)
                     /locus_tag="ACGI5H_001364"
     CDS             complement(15674..16189)
                     /locus_tag="ACGI5H_001364"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HFG9697075.1"
                     /translation="MLEYIILGFLMEKELSGYDLKQIMSESTSYFFDASFGSIYPALK
                     RLETKGYIHYHEVIDGSKLKKLYSITNTGKEVFLEWLKKPINFSKTKQDHLVNIFFYK
                     YLPKEIIETNLKMLITEVELLLNKLSKQKNDAEENHCVDQYTYMYATMIYGVDYYNFV
                     INWCKDLLKNL"
     gene            16469..16996
                     /locus_tag="ACGI5H_001365"
     CDS             16469..16996
                     /locus_tag="ACGI5H_001365"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422037.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family winged helix-turn-helix
                     transcriptional regulator"
                     /protein_id="HFG9697076.1"
                     /translation="MHEQIDYCERKKIRTIDIKGENMRELLKWVSIINRYNTNYIDRK
                     LADIGINNSQYFYVLHICNNPGITQDTIFEKILVNPSNITRALANLEKEGFITREPGV
                     KDKRTWHLYPTEKSLGCYDEILKITNGYVEELLSSFEKEEQELFMSMLKKVAFLAIDM
                     NEEAKLEAKENGRKI"
     gene            16980..18383
                     /locus_tag="ACGI5H_001366"
     CDS             16980..18383
                     /locus_tag="ACGI5H_001366"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438762.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0042910 - xenobiotic transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0006855 - xenobiotic transmembrane
                     transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MATE family efflux transporter"
                     /protein_id="HFG9697077.1"
                     /translation="MEEKYKEPLEYEKVSKLLTKYAIPSIIAMLVSALYNIVDQIFIG
                     QGVGVLGNAATNVTFPLTTICTAIALLLGIGGASKCSLELGAKNSEKATKAAGNSICL
                     MAVFGISLFIVVSIFLTPLLKFFGSTSEILPYAHTYTKITSIGLPFLIMSTGMSKLIL
                     ADGRPKASMFCMLIGAVINTILNPLFIFVFNMGIAGSALATVIGQLISFGISVHYIKN
                     FQHIKLHKKSFKLDSIIYKHIFALGSSSCFNQLAMTVTQIVMNNTLAYYGARSVYGSE
                     IPLACVGIIIKVNMIFISIIIGISQGMQPIIGYNYGAEKYNRVKEAYKFAVGSATIIS
                     VIAFLCFQFFPRQITSIFGNGNETYFIFAEHYFRTFLFLTFINGVQIVSSTFFTSIGK
                     SVLGLFTSLTRQILFLIPLIVILPMFMGIDGVMFAGPIADAAAAMVCIYFAVHEMKSL
                     TIKQNNLMSNHNKIAEV"
     gene            complement(18766..19077)
                     /locus_tag="ACGI5H_001367"
     CDS             complement(18766..19077)
                     /locus_tag="ACGI5H_001367"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422032.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9697078.1"
                     /translation="MKKIIKSFTSWFFLIALFEIYMHQIGQDSKSIVLIGLNPILSII
                     SRVDSFFVFMDSGMQIPCRTITGSISIYWYIASILSFLIYGIILDLIRIVISKIGNKT
                     K"
     gene            complement(19133..19726)
                     /locus_tag="ACGI5H_001368"
     CDS             complement(19133..19726)
                     /locus_tag="ACGI5H_001368"
                     /EC_number="1.7.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428032.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA];
                     GO_function: GO:0016657 - obsolete oxidoreductase
                     activity, acting on NAD(P)H, nitrogenous group as acceptor
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="nitroreductase family protein"
                     /protein_id="HFG9697079.1"
                     /translation="MISDSISKRRSIRKYKNQSISHETIEKIIEAGINAPSSKNRQPW
                     RFVVITEKEKESMLKAMSKGIQNEINDNGLLPGSRQHIAGANYTVEIMKQAPVTIFIL
                     NILGKSPLEKLSPEERFYEMANMQSIGAAIQNMSLTAVELGLGSLWICDVYFAYRELC
                     EWLNTDSQLVAAISLGYPDEEPSRRPRLQLSDVTEWR"
     gene            20577..21227
                     /locus_tag="ACGI5H_001369"
     CDS             20577..21227
                     /locus_tag="ACGI5H_001369"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YidC/Oxa1 family membrane protein insertase"
                     /protein_id="HFG9697080.1"
                     /translation="MDFISSILQGLLSILFNFTGDFGISIVLITLIVKLVLMPLSLKQ
                     RFSVKKQQELAEKMEHIKEKYKNDTKELEKQIQVSSVESMKSMLGCLIVLVQMPVVYA
                     LYHVCLDMTKEFTTIIIPWIANLGTFDNLFILPCIYTLIMLASNLVNYIPYLKINSQV
                     KFNKQMAVVTTITSLILTVRTPVAIGLYFITSAIYSLIEDICFRIYFNRKNRIVTK"
     gene            21441..22112
                     /locus_tag="ACGI5H_001370"
     CDS             21441..22112
                     /locus_tag="ACGI5H_001370"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422026.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000156 - phosphorelay response regulator
                     activity [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HFG9697081.1"
                     /translation="MAKILIVEDEKRMQSIIVEYMQKGGYTCITADDGVEALTILKSN
                     NIDLMILDIMMPYLDGFSVCRVSREMTNIPIIILTAKGEEEDKLKGYEYGADDYITKP
                     FSPKVLLAKVNALLRRYTTDIPKNSLSLGKIFIMVASRQVYVEDKLIDLTYKEFELLR
                     LFMENPNQVFSREKLLNCIWGYDFEGNTRTVDTHIKTLRKKLGSEGHHIVTLIRSGYK
                     FEVKE"
     gene            22109..23239
                     /locus_tag="ACGI5H_001371"
     CDS             22109..23239
                     /locus_tag="ACGI5H_001371"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861876.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing sensor histidine kinase"
                     /protein_id="HFG9697082.1"
                     /translation="MNSLRKIIEKLKNVDISNWIKQNFGLYSVRKKVFLLSKLSGALI
                     ILFYLVVEEFSINSKLEFWIWFIILVIFIMSIDFLLGKFISEPITSINKSAKSMSQLD
                     FSNPCTVNTNDEFGELSRSLNTMSTNLQQALSDLESANIQLEKDVNKERMLLEQRKEL
                     VDTISHEMKTPLGIIRAYTEGLMDEVDEEKKKNYMNVIIEETDRMNNMIVSLLDLSAL
                     EAGVSKLNPERFDFIEFVETVAGRLLIDIPDANFYFTYDLPEYEVFVVADKMRMEQVV
                     ENLVINAKKHVVYNGNLDLSITCENGLLLFEIYNDGRFIEQDEISKIWSKFYRSVQSQ
                     RTGGSGLGLAIVSQILTMQGLEYGVNNRDRGVEFYFMIPIDE"
     gene            23540..23662
                     /locus_tag="ACGI5H_001372"
     CDS             23540..23662
                     /locus_tag="ACGI5H_001372"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9697083.1"
                     /translation="MKWYTWLTIILIILLSIPLKIKFIKWWDRRQKNDKGGYDR"
     gene            23659..24504
                     /locus_tag="ACGI5H_001373"
     CDS             23659..24504
                     /locus_tag="ACGI5H_001373"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861875.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HFG9697084.1"
                     /translation="MIKVGELKFSYGKDKQILHGLNFEVKEGEIFGFLGPNGSGKSTT
                     QKILNGVLKGYNGHVSLFGKEVKAYTESLYQKIGVLFEFPYLYTNLSAIDNLEYFSSF
                     YPKNQRRDIYELLDLLEFKKEFINKPVSSYSKGMKQRISMARALVSNPKLLFLDEPTS
                     GLDPSGAVLFRKIIEEERKKGTTIFLTTHNMLDADLMCNNVAFIADGKIMVIDKPKNL
                     KMKNSNNKVEVEFVYNGNRDIEIVDIQELESGITFKYDEILSVHSKEPTLEEVFIKYT
                     GRMLV"
     gene            24504..25532
                     /locus_tag="ACGI5H_001374"
     CDS             24504..25532
                     /locus_tag="ACGI5H_001374"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434295.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HFG9697085.1"
                     /translation="MYSKFFTLVKKDFWMMIYGKFFVLTLGSLILYSCYINFGYVKFM
                     DEDSYHNNVYLYNPENISMSASPLINQVSSIGELKAKLDEDTSAVCIDMSSSKPKVIL
                     HESIKGVDDYRADYALSLLSSEKDHNSKISDNNAIIQINDKDTSEIKQRKDMTCEILF
                     FEIVAIGFLGIASLLFKEKQMGVMRITGILPVKRSLFILSKIFAFLICDLCFTVLLVV
                     FNIGFFEGIKILPQVLVQASILSIIMSLIGIGCSMLLRDFKQFSLIYLVVAVFITTPI
                     FLSANTSFEIDWIKYHPFYHVYSQLKNAFFMNFSKELVYFVVCSLTIIVLFLLVKYIF
                     NKELVREG"
     gene            25535..26548
                     /locus_tag="ACGI5H_001375"
     CDS             25535..26548
                     /locus_tag="ACGI5H_001375"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861874.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HFG9697086.1"
                     /translation="MIGLRYQLKSIKKDKMCIISFFLPVVMAILINFMGTIDISSLGE
                     IRFGIVKDTLPVQTEQWLKKYGMVSVYDTKMHLIREIKDIKTDTIGVVRDGKGIKTVL
                     YGNEINAIKNVGKTLPEMFRLKGDLKDVEVTILPKDSILKEFQNVFIAMILITAMFMG
                     CTFNAMNIISEKEDGISFINEVLPQSRSQYIIQKVFLGLLCGCLSSMITVFICLDISI
                     LDMIMMLLLVVFSAFISSLIGLFIGKLSEGLMVGIVYIKIVMILFIGTPLLIYLLGVN
                     TSGIGNLYYIMPSVATFNGIMEIINGNVIIIKDIVILAVHCVVWFMIYIILDKKRKLF
                     FSR"
     gene            complement(27065..28315)
                     /gene="cme"
                     /locus_tag="ACGI5H_001376"
     CDS             complement(27065..28315)
                     /gene="cme"
                     /locus_tag="ACGI5H_001376"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434293.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux MFS transporter Cme"
                     /protein_id="HFG9697087.1"
                     /translation="MENKNTNSTWKKKVILFLASQYISLFGSSLVQMAMIWYVTLQTS
                     SGVWVTVLTVCSFIPQMIISFFAGVWADYYNRKVLIIVSDSTIAISTLVLILFMMSSN
                     GTTSELIAISVISVIRSLGSGVQTPAVNAMIPQLVPEEHLMRFNGINSSLQSIVQFIV
                     PIVAAAILGFGNKINQVLLIDVFTAIIAIVLLIFIKIPKHDIPKQTEKVSFFADMVSG
                     IKYCFSDKFIRKVLFTYGAFMLLCVPSGFLIGLLIERTFGKGYIYLSIIEMIGFLGMV
                     LGGLIIGVFGGFKNRNKTFFLAILSYAIFSIILGLVTQAWQFFIFMFFTNFSIPIIQA
                     SAMTMLQEHVAPQMLGRVLSLPIIIYTGFIPLGMMIFGPMADVISINNLIIIAGIILL
                     FFALAIPYSKQFYKQGISKSNESE"
     gene            complement(28401..29147)
                     /locus_tag="ACGI5H_001377"
     CDS             complement(28401..29147)
                     /locus_tag="ACGI5H_001377"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903632.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HFG9697088.1"
                     /translation="MDTYTTSEVADLIGVHPNTVRLYEELNLIPKPKRNTNGYRIFND
                     FHIEQFRFARTALKIEVVQRGLRKDALEIVRTSANRDFDKAISLVNQYLQQLEIEKSN
                     AEEALTIVAQILNGNTPETNKLFLTRKETAEHLNVTIDTLRNWEMNGLLKVKRKQNGY
                     RVYTDEDIKRLKIISALRCANYSLSAILRMLNALSSNPNTNIKTVLDTPKDDDEIISV
                     CDKLITSLKEAEHNAKTMKSHLQIMKKQFS"
     gene            complement(29262..30284)
                     /locus_tag="ACGI5H_001378"
     CDS             complement(29262..30284)
                     /locus_tag="ACGI5H_001378"
                     /EC_number="3.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728517.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="serine hydrolase domain-containing protein"
                     /protein_id="HFG9697089.1"
                     /translation="MNKNNCLDLIFEKVNPSSVGMSSEKLSQLEPLIISQYSNINGII
                     IARKGKVVFEKYYNGYNADDTFHVASVTKSIISALIGIAIDKGYIKDVDQKVVDFFPE
                     YTYSPSEICKKAVTIRHLLTMTAPYPFKNMTESLERLCKQKDWIKYTLNQLGQKGEIG
                     TFKYSSAGTHLLSAIITKTTGKSAREFANEYLFKPIGMKVIPDYDMKDFGFEDFFGKN
                     LKGWAKDRQGYSIGGWGLTLSARDMLRFGFLYLNDGIWNNKRIISKSWIEESVKMNSN
                     EYGYLWWLCKKDGVLWYSAMGAGGNAICCIPQYDLVIAIPSKIVFKPRDRWEFIEKYI
                     LTSIID"
     gene            complement(30284..32704)
                     /locus_tag="ACGI5H_001379"
     CDS             complement(30284..32704)
                     /locus_tag="ACGI5H_001379"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422012.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="excinuclease ABC subunit UvrA"
                     /protein_id="HFG9697090.1"
                     /translation="MKEIKINGAKIHNLKNIDVSIPKDKLVVATGVSGSGKSSLMFDI
                     VFEEGRKQYLQSLGILAGIDSEDKFDNIQGLAPTIAVQQNIIRQSNPRSTVGTRTNIL
                     NMLTLLYSVEGQIMCTMCDTPVSYNLICNNCGYEEERLRPSYFSYNSSDGMCMKCSGH
                     GAYFEINIEKLVLDKHDTLKQVLDRAKITPGYLRVFSKKFNDYLDIQFLQLPEEVRNE
                     VLYGHYENGKKSSSLSKVFHNRYKRGEDLNGVYTMTACSDCNGFKIGEEARRVLLNGK
                     HIGELGKMTILEIDDFLKLLINQGNLNTFGTNLVNDILSKTQHLIESRLGHLSLYREM
                     STLSGGEMQRLFLNSHLDSEMDSLIYVLDEPTAGLHESEKIDILKSIKKLKDLGNTVI
                     VVEHDKNTIKMAEHIIDIGPKAGVEGGQLVYQGDLEGLLQSDKSLTGQYLSGKYPMPN
                     RTSNKNITHTDKIPCITIQNANTNNLKNVTVSLPLGAMVGISGKSGSGKSSLISDTLL
                     PLLRSQFNNHTINNQINSSESEIGEEDDYAVVETIADRLIGTKHISGYSEISQSPIGK
                     NMNSTPASYIGIWDKIRTLFAGQPESLERGFTAGHFSFNSKGACPKCSGSGYEKVWLG
                     NNLSIDHICSECQGKRFNDESLSIKYKNKNIHDILNMSVSESVHFFKDIPNIVSHLNV
                     LEQIGMGYIKLGQPTPTLSGGESQRIKLAKEIGKKRNGNILYVLDEPTTGLSLYDTSK
                     LIQLLDELVENGNSVIVVEHDIDVLNVCDWIVELGPEGGDKGGYIIAEGSPKTLKENP
                     KSITGRYL"
     gene            complement(32790..33710)
                     /locus_tag="ACGI5H_001380"
     CDS             complement(32790..33710)
                     /locus_tag="ACGI5H_001380"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891624.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GyrI-like domain-containing protein"
                     /protein_id="HFG9697091.1"
                     /translation="MTNAKSKKEYLNRICKVQDYIEEHLHEPLSLDELSNIAGFSKFH
                     FHRIFKAIEKETLAQYVNRLKLENATAFLIHRTDMTVTDIAHYFGFTDSAVFSRAFKN
                     YYKISPIKYRNNYSKNCKEPYKISQYNRSISKPKCKNTREVKGEIEILELDNMNTIYT
                     RYTGSYGNLTSTFPKLLERLFTYASEQNLLGLENTQILAIYHDNPQFTQEHQLRTSIC
                     MTIPDNIVVKENDNLGNMIIPSGKYLVGHFDISKSEYSDAWDFMYNEWLSNGNYKLRA
                     SFPFEVYLNNPHNHPQNRHLVDIYLPIEPF"
     gene            34320..35246
                     /locus_tag="ACGI5H_001381"
     CDS             34320..35246
                     /locus_tag="ACGI5H_001381"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434288.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conserved phage C-terminal domain-containing
                     protein"
                     /protein_id="HFG9697092.1"
                     /translation="MSNSFYQLNSAVLYFNEKRDVNRIRFNHYVMRKENIQRLKGTLP
                     RGQFMMTVRKAASDLDVSISTISRLVNEFIDLGILRLISRGVKGNCCSVYSYVCSESS
                     NAEIVTKNGDIFKNIEKYIDATINNNQKTMKYKHRNELFKNSNTNIYSRINQESIDKD
                     YDLIIHTGYETENETKKKELLKNNLNKKNLNKNTFENSDEDLTEDSTYKNPESIHEII
                     IRKLNSESGKNFKADLSITKALIDKRLKEGYSLEDFYKVIEAKVRRWRYTDMEIYIEP
                     TILFGYEFESYLNEESSLSACNYGDMCYEDMY"
     gene            complement(35435..36055)
                     /locus_tag="ACGI5H_001382"
     CDS             complement(35435..36055)
                     /locus_tag="ACGI5H_001382"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003431574.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator"
                     /protein_id="HFG9697093.1"
                     /translation="MVLINILLVDDHMLFAKSLSIALEEYKEIEQFYSTQDIHNLSEM
                     IQDKKIDIVLMDINLRGLSECDGLKVAYNLLETNSTIKIIILTGYDLPVYKHEAKKIG
                     IYGFLNKNISPDSLIDSLLKVYQGVTCFPSENTEVIIEDLTTMEKRILQLICSGKKRK
                     IIADELYISERTLSNHLQHIYDKLDVSSSVEAITKAIKMGYISPVY"
     gene            complement(36027..37610)
                     /locus_tag="ACGI5H_001383"
     CDS             complement(36027..37610)
                     /locus_tag="ACGI5H_001383"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903621.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HFG9697094.1"
                     /translation="MTNFNLKILFLGNYILSLLFMGISTSTETYMNIQSIIPLIISTL
                     LLIDITYITSCNVRENNIISLFCGLLALDSWYLLLSFVTTPIGTIIFKILSTVIVYVS
                     IKFIFLFLFQGSGYNFRKITDILLLITCIGAIVGAFISNRTYACMYGIQFVVSIISFF
                     YIIFYHLKRVVFVIKSEKKPISISVFITIIGFLTYYFFTLRISNHIGNFGIYLTVLVF
                     FMSIHGIALKENDSFPISTVFNIKQRAIFLFISILVISLVVLFANGNFSIILIAINVL
                     FMLIFLCNIILEFNLRDEKNKVVKNSKYTFALEKLQQEEQLKTEFSNFLHDDILQNLL
                     SIKNMMSKSYRPDVQDIIYETLNNLNTCIRKQMQDYHPVILKNLTVKENYQNLIESVS
                     SSFPQKNICVSFKCSDTLFLVEPYDILIYRLIKELLTNVYKHSNGSHAWIALALEKNI
                     IKLNISDNGVANTSFKTPLDITKITFDTIKHKGIISIKEQVENLGGTISVSDNIPHGV
                     CVQITIPMKGDGSYKYFVS"
     gene            complement(37754..39781)
                     /locus_tag="ACGI5H_001384"
     CDS             complement(37754..39781)
                     /locus_tag="ACGI5H_001384"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903620.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="FtsX-like permease family protein"
                     /protein_id="HFG9697095.1"
                     /translation="MNIFYTAIKNLKKNFSFYSLYLLSVSFVITVFFAFTSFSVNKIM
                     LEKISTDGRVESMCNVISIFLMAFVIFYMAYSNRFFLRRRTKELGIYALLGYRKFTIL
                     SLLTFENVLICSGAFIIGLVLGALAHKGIVFGITALLNLSIDNSQIPFFNINAINKTI
                     IFIALVVLVLAVSNGKFFYKTPLVKLIRYEKSAEKKLKFRKIPAFMGFIMILSGYCLS
                     LDILRGAKSVWVSIGFYQMGLITMIIIVIGTVLFINSFLPYIMQNSKKNKRTFYTDMK
                     IIAIPNFIYRIRSNSKTLIMLTLLSATTLTVSSVMALSLYYPIASVSRIAPSEIEFRV
                     EKNKQIEDVKQIVSQYTSNTDDIIFTQTNIYKVKSSSKDLPFEYEIGTSKNNLSNSSS
                     SKEVISRESGFECISFSDYYTLLKAQNRTKLLKQLTPLRDNECILMKYQPNNDGYSEN
                     GTIYPLLVNGKETPVAVRETSLNNAISFANSVGTLIVNDSIYEQIAQNKLPMTRILSI
                     NGKSIKNNENLYSNISDYLDGSPYLQGYSHRINDLLSINSSTFLLIGFLVVLFFIAVG
                     SILYFNNISAISDSTSDYKILQKMGYTNIQIKKIIKKQVLPFFNIPFLLGIVDCIFAT
                     LVYKTALMQNLLGNSLSQYIPVIIAIFLTSVVYLIYYILTIKSCCKIVLKK"
     gene            complement(39794..40543)
                     /locus_tag="ACGI5H_001385"
     CDS             complement(39794..40543)
                     /locus_tag="ACGI5H_001385"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005340256.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HFG9697096.1"
                     /translation="MNTILKVNNITKTYNKGQQPSLDKVSFNVSEGEFIGIMGASGSG
                     KTTLLNVLSTIDKPTSGDIFINNINLKSLNDTCAADFRKDNLGFIFQEYFLLDSLTIF
                     ENISVPLTLQKLNPDKIENMVKSLAERFGIASQLNKYPNELSGGQRQRASAVRAIVKH
                     PSILFADEPTGALDSNSATELLHSLQEANEELKTTILMVTHDAYVASFANRILIFKDG
                     HIIKELNKQQNNRHTFYELIIQEIAKLDTKR"
     gene            complement(40842..42494)
                     /locus_tag="ACGI5H_001386"
     CDS             complement(40842..42494)
                     /locus_tag="ACGI5H_001386"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861871.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall-binding protein Cwp21"
                     /protein_id="HFG9697097.1"
                     /translation="MNKKNLAILISGIMFFSSSSAIFADNTTKQERLIGKTRYETAVE
                     VSKLGWVQSKTAIIVNGNSIQSALCANPFAKLKNAPILLVNNNSIENSTKAELKRLGV
                     DNVYIVDSGNSISSKVENEIKSLNIKINKIVGNNIYEMSTNVLKEIDKIKKVENVAVV
                     NGLKGLSDAVSIASPAAIHNMPIILVSDENSNDSSINFLNNRSIKKSYIVGGNKILSD
                     NTVKKYPNRERISGSDRNNTNAKIIDKFYKDKKINNVFVAKDGINQENALVDSLSIGV
                     LAAKENSPIMISNGSLVNSQKEFIKNKDIDEITQVGGGYNQKAFEDILKLKNVNIRNK
                     TKKISLIQAKEILKQALPGSNILVCYYDEDDNEYDCKVIKDNILYEIEIDAYSGKIIE
                     IEKDDDLNDNNLGTQNISLDKAKSIALDAVPNGNLIYCKYDAEDNEYEAKVIKNKKTY
                     ELEISAFDGRIVDIDMDNDSDDDFDDNDKNNSNTNDNSSIISAEKAKSIMLDKVPGGK
                     IVKFKYDEDDKEYEGEIIKGKTEYEITINAITGKILEFEIDD"
     gene            43082..44203
                     /locus_tag="ACGI5H_001387"
     CDS             43082..44203
                     /locus_tag="ACGI5H_001387"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434286.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldo/keto reductase"
                     /protein_id="HFG9697098.1"
                     /translation="MEAKKLGFGLMRLPIKDENDVTTIDMEHLNKMVDTFLERGFTYF
                     DTAYVYHMGKSEIALRESLVKRHKRESFTIATKLPLMALKKKEEQETIFNEQLEKCGV
                     DYFDYYLLHNIGVSHYEVAKKFDSFKFIEEKKKEGKIKNIGFSFHDSAELLDKVLSEH
                     PEVDFVQLQINYLDWDNESIQSRKCYEVAEKHNKPVIVMEPVKGGTLAKIPEKAEKLL
                     NDYNPDMSISSWAIRFAASKDNVMMVLSGMSNMEQLLDNTGYMQNFKPFVQEEYNIID
                     EAVEIINESILVPCTACQYCVEGCPKNIAIPNYFALYNAEKQALNTGFSTQMVYYNNY
                     TKTYGKASDCIECKQCEESCPQHIKIIDALKNVAETFEK"
     gene            44239..44652
                     /locus_tag="ACGI5H_001388"
     CDS             44239..44652
                     /locus_tag="ACGI5H_001388"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434285.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HFG9697099.1"
                     /translation="MTISEVSKKYELSADTLRYYERIGLIPPVNRNKSGIRSFTEEDC
                     EWVNFIKCMRGAGLSIETLIEYVAMFQQGSSTIKARKELLIEQRNQLAKRIEEMQKTL
                     ERLNFKIDRYEEGIIEKEKVLKSSRNKKMEAVSYE"
     gene            44645..45184
                     /locus_tag="ACGI5H_001389"
     CDS             44645..45184
                     /locus_tag="ACGI5H_001389"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434284.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0009055 - electron transfer activity
                     [Evidence IEA];
                     GO_function: GO:0010181 - FMN binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="flavodoxin family protein"
                     /protein_id="HFG9697100.1"
                     /translation="MSKNVLIVSASPRKGGNSDLLCDQFIQGVLESKNQVEKIFLKDK
                     DINYCTGCGACYEKEANCSQTDDMGEILEKMIEADVIVLATPVYFYTMNAQMKTMIDR
                     TCSRYTEICDKDFYFIVTAADENVADMERTIEGFRGFTSCLNGSKEKGIVYGVGAWNV
                     GDIKGSKAMKQAYEMGKLA"
     gene            complement(45384..45869)
                     /locus_tag="ACGI5H_001390"
     CDS             complement(45384..45869)
                     /locus_tag="ACGI5H_001390"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434280.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9697101.1"
                     /translation="MSKSELTAETTEEMLEVLSGKDYDIACHLHELGKSLDCKIEPKT
                     GARSYKIVYSTKKPKRSLFTIECNEKKWRVKANLFHLNTYKDAVEECSKTIKDSITKT
                     RTCKKCNSKCIGGSSFELDGKSYLTCIGSGHYFANMEEMDWKNLEKLITKENNIMQES
                     V"
     gene            46774..47151
                     /locus_tag="ACGI5H_001391"
     CDS             46774..47151
                     /locus_tag="ACGI5H_001391"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421988.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RidA family protein"
                     /protein_id="HFG9697102.1"
                     /translation="MSKVVIATEKAPGAIGPYSQAIQVGNIVSTSGQLPIDMKTGELV
                     SDPKEATKASLDNVKAILEQAGTSMDKIFKTTVFVKDLKDFNDINEVYATYFKENPPA
                     RSCVQVAQLPKDAVLEIEAMAVL"
     gene            47547..49352
                     /locus_tag="ACGI5H_001392"
     CDS             47547..49352
                     /locus_tag="ACGI5H_001392"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891601.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0008134 - transcription factor binding
                     [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sigma 54-interacting transcriptional regulator"
                     /protein_id="HFG9697103.1"
                     /translation="MLSKLKEFQQEMIKYTETVASVLDVDIEIVDDRLIRISGTGLYK
                     SKINESVVTEGFIYDNVIQTGQELVVLDICDNQLCIECSHYMKCLNKVIIAVPIKYNN
                     RTIGVIGAISTDKTKKVEISAKIDNYLKFVNHICDLISMKIEEHEASKNSSRKMDMMI
                     EIIENVEKGVIILDINSKISYINNIALKKLDIDKNIIENIVNIVSVESSSNGHELLEI
                     DIDNKIYNINAKIIPVYPYINQYDKIIIFDKTYINHKGHGKVNSGWGNSDIESIIGNS
                     EAMLKVKERTKKLAKSNSTVLITGESGTGKELIARAIHAEGSRWNKPFIAINCAAIPE
                     NLLESELFGYIKGAFSGASSGGKVGKFELANEGVIFLDEIGDLSMPLQAKLLRVLQER
                     KFARIGSNKLIDLDIRVIAATNKNLLKLVNEGKFRDDLYYRLNVIPINLPPLRERKDD
                     IEAIMMKFASKYSLELGIQLNKIEENVMNMLINYNWPGNIRELENAVEYMMNLVGDDG
                     IIYKDMLPLDILNYYNINGNIYKNKDVNIIFEDDIVGGIVENQERILSIKELELTYIN
                     KLLNKYGRDTKTKKKIAKDLGIGLATLYRKLEEEQ"
     gene            49429..49716
                     /locus_tag="ACGI5H_001393"
     CDS             49429..49716
                     /locus_tag="ACGI5H_001393"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9697104.1"
                     /translation="MQYAIELYYDKKTEKQLFDLSKKIADEKISTKYLEWKTRPHLTL
                     ACFNDVDEACCIDKLKGFAQNHKVIPAYIGSVGMFNDTKTVFVSPIMNSSM"
BASE COUNT        18713 a         5968 c         8215 g        17534 t
ORIGIN      
        1 ttagaaaaat tttaaataaa tgttttattc tcaaaatatg catattaatt taataaaata
       61 taccaaaatg gaaataaaaa ataaatttta tgagaattta ataactaata attaatatat
      121 ttaggttata ataaatatgt gcgtaaaatc taacaataag caataatacc gtaaatttag
      181 gaggaataat atggatactt taaaggaact ttttaaaata ggaagtggac cttcaagttc
      241 tcatactatg ggaccacaaa gagcagcaga gagatttaag aatgaaaacc cagatgcaga
      301 aagttttaga gcaatattat atggtagttt ggcagctaca gggaaaggtc acttaactga
      361 ctatataatt gaaaaaacta tagcacctaa aaaagtcgaa attgtttggg aagaagatat
      421 tataaaagat tttcacccaa atgggatgaa gtttgaagct ttagataaag ataaaaatgt
      481 aacagctgaa tggactgtat attctgtagg tggagggact atagcagaag aaggtcaaag
      541 aaacagtaaa agcaatagta tatatcactt agatactatg gatgagatag taaaatggtg
      601 caaagaaaat aataagactt tggtagattt tgtgttggaa tgtgaaccaa aagacataaa
      661 agattatata aaaactataa aagatgctat gagaaaatct attgatgatg gactaagtac
      721 agatgaaata ataccaggca agttattatt aaaaagaaga gcaagtacat tttataatgc
      781 atataaaaaa gataagagct tctcaacact tgtatatgca tatgcactag cagcttcaga
      841 gcaaaacgct tctggtaata taatagttac agcaccaact tgtggttctg ctggagtaat
      901 accaggaata ttctttgcaa tgcaggattt ctataattat gatgacgaaa aaataattga
      961 agcactactt gtagctggaa taataggtaa tataataaaa actaacgctt caatatctgg
     1021 agcagaggta gggtgtcaag gtgaagttgg agccgcttgt tctatggcag cagcagcagt
     1081 agcatactta aaaggtggaa ctatagacca tattgaatat gcggcagaaa tagcacttga
     1141 acatcattta ggaatgactt gtgaccctgt atatggatat gttcaaattc catgtataga
     1201 aagaaatgca atggcagctc aaagagctta tgatgcagct aattatgcat tattaactga
     1261 tggctcacat tctgtctcct tagaccaagt tgttgaaaca atgaaagaaa ctggtataga
     1321 tatgatggat aagtacaaag aaacagctaa gggtggactt gctaaacatt tcttctcttg
     1381 ctaaaaataa aattttccaa taataattcc tctgttttga tttatgaaac aggggaatta
     1441 ttattaatgg tgaattattt aataatgcaa aatattttta tattcaattt agctttttat
     1501 ttttaattag tataacatgc tatataatat tttaattata aagaaatata gaaatatttt
     1561 ttaataaatt agaaattgga ggagattaca tgagagaggc atcatattta caagaacaac
     1621 tttataaaca taggaagtca ttaaatccta ttgcagagat tgggagaaaa gagtataaga
     1681 cttcaaaata tataagagat tatcttgata aattaggaat tgagtatgaa gtttatttag
     1741 aaacaggtat agtaggtgta atagaaggta aaagacctaa aaaagatatt gcttttagag
     1801 ctgacataga tggtcttcat agtgaagaag gggtaaaaca tttatgtggt catgatggac
     1861 atgctactat attacttgga ttaattgagt atttaaatga taataaagaa gacttaaatg
     1921 ataatatagt atttatattc caaccagcag aagaaggtcc tgggggagca aaagctttaa
     1981 tagatgaagg agtgcttaga aaatacaata ttgatgaaat atatgggctt catatatatc
     2041 cagagttacc agaaggttat gtaggtacaa gagagggcta ttttatggct caaataggag
     2101 atattgacat agaaatagtg tctaaaagtg gacatggggc tatgccacaa aatggtattg
     2161 atggtatagt gatagcttca aactttgtaa gctcacttca aactatagtg tctagaaata
     2221 taagcccaat agacaatgca gtgttgacta ttggtagaat tgaaggggga gctagaagaa
     2281 atataatagc tgaaaatata aagatggaag gtactatgag atgtttcagc ccagaagtgt
     2341 atgagaaaat gaagcttaga gttagagaac ttgctagagg gtttgaattg gcttataact
     2401 gtaaggttaa tataaatatt atagatgatt atattgctgt taaaaatgac aaggatttgt
     2461 atcaagagtt tgtagaggct attggaagtg atactgttgt agagttagag ccacttatga
     2521 tatcagaaga tttttcttat tatcaaaaag aagttccagg attatttttt atgttgggtt
     2581 caagaaacga agaaaaagga tttgtaaatg gtcttcataa tataaacttt aattttgatg
     2641 aaaagatatg tgtaaatgca ttgaatgttt attcaaaatt attaaaatac aaagaagcaa
     2701 tagattagga agataagtta taaagattaa aaagcataaa tacctaaatt taaaaaaagt
     2761 gtattaataa atacccctta catatttgta taaatttatt ttaattgaca aaaatacaaa
     2821 taagaagggg tgattttttt gaaagaaaaa gtacaaagag aaaagaagat aactaatggc
     2881 aagaatacta aaatattgac aaatgatgat ataatgaaat atgagatagc ctcagaacta
     2941 ggtcttatgg ataaagttgg tgaacgtgga tgggcaggac ttacagctaa ggaagcagga
     3001 agaattggag gtatgcttac atcacgcaaa aagaggctta aaaagattgt ggaggagcag
     3061 aataaaaagg atgagtcaat atagtgattt tgcgtttgta tatgatgaac ttatgaatga
     3121 agttgattat aatggttggg ttaaatatat agaagatata atagatagtg aaggtgtaaa
     3181 agtaaaaaat atattggaat tggcatgtgg cacgggtaat cttacaattc cattgactaa
     3241 aaaaaattac gatatagctg gtatagatat atctgatgag atgcttagtg tagcaagaga
     3301 aaaggcagaa aaagaaggag tagaattagt tttacttcaa caagatatat cagagcttga
     3361 ttttgaaata tctgatttgg actgtgtact ttgtgcttgt gatggattta attatataac
     3421 ttatgatgat gatttggaaa atgtattttc aaagacatat gaattattaa agaaagatgg
     3481 aatattcata tttgatataa gttcttttta taaattagcc aacatattgg gaaataacat
     3541 gtatggagaa aatagagaag atatagcgta tatgtggcaa aattactttg atgaagaaga
     3601 gaatctaatt gaaatggaac ttacattctt tattaaagat gaatgtggaa agtttgaaag
     3661 atttgaagag atacaccaac aaagagcata tactgaagat gagatagttg atatgcttga
     3721 aaaatctgga tttaaggata taaaatatta tggggatttt acatttgaca aacctagtga
     3781 agaaagtcaa agaatcttct ttgtatgtaa aaaataagat attcttgact atataagata
     3841 attattaaaa ataaccatga tataaaaata tataaaatgc agttttatag attaaaagta
     3901 aagtgatgat attttatgat ttttattttc taataattat aaagttttat agataaaaat
     3961 taaaatataa taactattgc ttagtaaaat taaaataaaa tgggttttgc ccaaggttaa
     4021 gatagataag tatttataga ttaaaattaa ggtagtaata taataaaaat aagacaatta
     4081 acgggacatg gaggaatatt aatgagagat tatgtactaa gagcgacatc aggaaatggt
     4141 caagttagag catttgtcgc aactactaga aatacagtag aagaagctag aagattacat
     4201 gaaactacaa aagtagcaac agcagcactt ggaagaacat taacagccac atctataatg
     4261 ggattaatga tgaaaaatga tagtgataaa ttgactgtaa taataaaagg tggaggtcca
     4321 attggaacta ttatcgccac atcagactct aagggaatgg taaaaggata tgtaggaaat
     4381 ccacaagtag aggttgaaga ctatccaaat ggaaagttaa atgtagcagc agcagtaggt
     4441 acagaaggtg ttgtaaaagt tataaaagac ttaggtctta gagaaccata taatgggact
     4501 tatccattgg taagtggaga aattgcagaa gactttactt attattttgc tgtatcagag
     4561 cagactccat cagtagtagc tttaggtgtt cttacaaaag aagatgaagt agagtttgct
     4621 ggaggattta tagttcaatt aatgccagat gcagaagaag agactattgc taagttagag
     4681 gaaaatgtag ctaaattacc ttctataact aacatgttaa aagaaggaaa atcaccagag
     4741 gatatattaa atattgtttt ggatggtttg gaacctaaaa tacttgatac ctgtgaagtt
     4801 gggtttatgt gtgaatgttc aaaagaaaga gtaaaaactg ctttggttgc aattggtaaa
     4861 aaatcattgg ctcaaataat agaagaagat aaaaaagcag aagttggttg ccagttctgt
     4921 aataagaagt atatgtatag tgaagaagag ttgcttgaaa ttttaaagga aatgtagact
     4981 ataaaaatag ttgtattgat ataagtaatg ttatagtaat atagtaaagt cgtattgata
     5041 tagtaattaa agtataattt attaataata gacatattta tattaaaaaa taagtttaat
     5101 aaatttttaa gcttaataaa ttttaagaat taagaagctt tctggctgta atgtttgcaa
     5161 tgttgcagtt agaaggcttt tttattttat tatagttcgt gtcaaagatt gtatgaaaca
     5221 ataaaatatt gtaaaataat ttgtatattt agacctgatt gacacaaagg tttataagat
     5281 atttgagttg attatacgaa attctatgaa gtagtaaccc tgtgacttta atcatgggag
     5341 gttcagaaga aggagaaaat tttaaatatg gaaagtaaaa cgaagtacat aggaataagt
     5401 atattaatat tattgatgat atttttaatt gcaaagaatt ttaacggaaa acttgaaata
     5461 cctattcctg agagtaatag tagaaaattt aaatcagcag cagtgtttta tcctcaacat
     5521 caagatgatg aggttttatg gggaggaagt gccattgtag atgctataaa acagtgtggt
     5581 gttgataatg tatatgtggt attagtatca gatggttctg gagttaacgt tttcaaagct
     5641 aacacaaaat ttagaaattt aactaggaag caaaaggaag aacttagaaa taacgagttt
     5701 aaatcagctt tgagagagct tggagtgaaa cctcaaaatg tgattatact tgcagatata
     5761 gataaaaagg aaggcacaca ttatgaatta atggaaaaga ctatattgga ttttgaacat
     5821 aagtttaaag gcaatgtgac ccatatagcc catcactata agtatgatga ccatataatg
     5881 catagaaaga atggggaagt tttaaagaaa cttaaacgtg aaggtaagat aaaagatgac
     5941 ttgtattttg ttaagccaaa atatgtaaag tatataccaa gaaatgaaag agctatctat
     6001 aaagcaatgg attttgatga ctacaataag gttaagagtg cttgttatga atataaggtt
     6061 gtaaattcaa agcgtaaaat gtatggtata ggatatattt cggcacatag ttattttgaa
     6121 catcttctaa atgaccctga acttacgtct gtattaagtg aagattaatt tcttataagt
     6181 agtaagttat gtttgataag ttgattggaa ttttctatag ttttgaaggt attggaaatt
     6241 tagttttatt taaagattta aagatagagg tttttagtgt ttaaaatttt aaagttaagt
     6301 tgaataattg tatagaatta tttgtgaaag aagaaacagt gtaaaacata gtatcttatt
     6361 tatggtttta aaatcatagg caagatactt tttttatgta actaatacca ttttgagatt
     6421 attaacttaa gaattttata taatttaaca ctcatatata atgatgatat ttaggtagaa
     6481 tagatgtaat tacgcttaaa taaaataact gtatttttta taaaaatcca aaccctacac
     6541 tatactacca gataaaatct acatgctata atttgacctg tgtttataaa aaaaggagta
     6601 atctaataaa atagtatttc acttatgtat aactaacaac tattattacg attttctcta
     6661 aataatttaa agaaaaataa tgcaggaggt aaaatatgaa caatgaattt ataattttaa
     6721 aaggttgcaa agagaacaat ttgaacaata tttccttaaa aataccaaaa agaaaaataa
     6781 ccatattcac aggggtgtcg ggttctggaa agtcatctat tgtatttgag acaattgcaa
     6841 aagaatcaca acgccaacta aatgaaaggt ttagtacatt tgtaagaagt tttttaccta
     6901 agtatggaga ggttaaagct gattgtatag aaaatttgtc aacaccaatt atcatagacc
     6961 aaagtagact tggtggaaat tcaaggtcaa ctctaggtac tattacagat gtaaattcct
     7021 ttttaagagc tttatattca aggtttggta gtgagtatat aggtaatgcc aatatgtttt
     7081 cttttaataa tattgatggt atgtgcccac actgtcatgg gcttggaaaa aagctagttc
     7141 ctaatatgaa ccaaattctt gatatgaata aatcattaaa tgaaggtgct atattgcttt
     7201 cagggtttgg agtgggttct tggcattgga atatattcgc tgaatcagga ttttttgata
     7261 ttaataagag gatatgtgat tattcagaag tagaattgga aaagtttttg catggtaaag
     7321 cagaaaagat taagatagaa aatgctggtc aaactaacat gacatatgag ggattaatgg
     7381 ttaaatttaa tcgcctatac ttaagtagag agggagaaat atctgaagct actaagaaaa
     7441 aattgagtaa acttcttata gaagatagat gtcctatatg tgatggaaga agacttaatg
     7501 aaagagtata taggtcttta attaatggtt ataatatagc agatttaact agtatgcaaa
     7561 ttgatgaatt ggctgaagtt attaaaagta tagatgagcc agaagcacaa cctttaatta
     7621 aaggaataat agaaaagtta aacagtatca tagatatagg tcttggatat ttaacactag
     7681 atagagagac atcttctcta tcaggagggg aatctcagcg tataaagatg gttaagtatt
     7741 taaatagtaa tcttgttgat ttaatgtata tttttgatga accaagtgta ggacttcatc
     7801 caaaagatgt gtataaatta aataatcttt taaaaaaatt gcgtgataaa gggaatacaa
     7861 ttatagttgt tgaacatgac ccagatgtta ttaagattgc agaccatatt gtagatgtag
     7921 gaccaaaggc aggtaagtat ggtggagaag ttgtgtatga aggcagttat gaaaatctac
     7981 ttacaagtgg tactttgaca gggaatgctt taagtaaatt tcttcctatt aaagaaagtg
     8041 taagagaaca tagtggatat ttagaagtta aaaattgtaa taaaaacaat ttaaaaaatg
     8101 tatctattaa gatacctaaa ggtgtattga ctttagttac tggagtagca ggagcaggta
     8161 aaagtacatt gattaaggat gaatttttaa agcaaaatcc tagtgctgta cttatagacc
     8221 aaagccctgt ttcagcaaat tcaaggtcga gtttggcaac atatagtgga attatgaaca
     8281 acataagaag catattttca aaaacaaatg gcgtaaatgc ttctttattc agttcaaatt
     8341 cagaaggagc ttgtgataac tgtaagggtt ctggaatagt agaaatgaat cttgctttta
     8401 tggagagtat aaagagtacc tgcaatattt gtgaaggtaa aaaatttaaa aaagaagttt
     8461 tagaatatag gtttcaaggg aagaatataa ttgaagttct tgaaatgtct gttttagagg
     8521 caattgagtt ttttaattta aaacagatta aaacgaaatt acaatgtatt gaaaaaatgg
     8581 gtattggata ccttacttta ggacaaactc ttgatacttt gtctggagga gagtgtcaaa
     8641 gattaaagct tgctagtgaa ttaaataagg aaagttcagt gtatatatta gatgaaccaa
     8701 caacaggtct tcatatggct gatattgaga attttataag tataattgaa gagattgtag
     8761 ataatggaaa tacggtcata ataattgaac acaatataga tgtaattaaa agagctgatt
     8821 ggattattga gctgggacct gaaggaggaa caaaaggcgg gagagtaata tttgaaggta
     8881 ttccaaaaca attatgtaac aataaaatat cattaacagc aaaatatata gtataataaa
     8941 taaaatataa taaaattata atgatatttt aataaatata atgggtatat aaaatgataa
     9001 ttaaacttaa cagtaataaa taatgtgaga aatattcaaa tttaattaaa taaagtgtca
     9061 gaaatttgtt taaattttag tattttaacg gttctgacct tttttcttat ttttatggag
     9121 aatatcgagg atggagtctc taatagttac ttttttgtgt ctacttgcaa gtttgattaa
     9181 aaaatggcta tacacacttg tgacttcagt catgggaggt tcagattata atcttaatat
     9241 ataatttgtg aaataatttg atgacgattt gctgatgtat aaacaataaa gattaactac
     9301 attaaaattt aaatcttgtt aagtaaaact tataaaagga gagagatgga tgataaatga
     9361 tattctaacc ttattatctg aaagaagtga tttttttata aagctatcca tagaacattt
     9421 gatgatttct attatttcta taataattgc gattgttttg ggtggtataa ttggtattat
     9481 tgtaagtgaa tttcataatt cttctaaacc tatattggga actatcaatt ttctatacac
     9541 cattccatct atttctatgc taggatttct gataccattt tccggaattg gaaatactac
     9601 tgctgttatt gcacttacca tttatgcatt attgccaatg gttagaaata catatactgg
     9661 aattactaat gtggataaaa atattcttga agcagctagg ggaatgggaa gtacagattt
     9721 tcagatattg tataaaataa aacttccgtt agccctacct gttattatgt ctggtattag
     9781 aaatatggtg attatgacaa ttgcattagc tggtatcgct tcatttatag gtgctggagg
     9841 cctaggtgta gccatatata gaggaatcac gacaaataac acaataatga caattactgg
     9901 aagtatactt attgctctat tagctttaat atttgatttt attttagggc tggtagaaaa
     9961 attttttcaa cgaaaaagaa aaaagaaaaa taggaaaaaa gtttttgcca ttctaggaag
    10021 ccttattctt atagtaatta tctttacgtc ttatttattt aatccttcaa agactcaaac
    10081 tattcatatt gctactaaac ctatgactga acaatatatt cttggtgaga tgttggatat
    10141 tttaattgaa aaaaacacag gtctaaacgt ggaaattaca caaggtgtag gagggggaac
    10201 atctaatatc cagccagcta tggagaatgg agaatttgac atttatccag agtatacagg
    10261 tacaggctgg aatatggtac ttaagaaaaa tgaattatat actgaaagta tgtttagtaa
    10321 actacagtcg gaatacaaaa ctaaacttaa aatgcaatgg actggtatgt atggtttttc
    10381 taatagctat gcattagcag ttagaaaaga agttgcagat aaatacaatt taaaaaatat
    10441 aacggactta aaagatgtat cttctaaatt gacatttgga gctgaatatg acttttatga
    10501 gagagaggat ggatatactc cattgtgtaa tacatatgga ctgaacttta aagatacagt
    10561 tgatttagat attggattaa aataccaagc tatcaatgaa ggtaagattg acgtaatgcc
    10621 tatatttaca actgatggtc agtatagtgt ttcagatgtt gtagttctaa aagatgataa
    10681 aaatttctac ccatcttatc aatgtggaaa tgttgttcgt ttggaagtat tagaggaaaa
    10741 tccagaacta tcaaaggtat ttaagatggt tggagatatt ttgactgata aagaaatggc
    10801 taaaatgaat tatgacgtag aaaacaacaa tttagaacct agagaagttg ctcgtgagtt
    10861 tctgaataag aaaggtcttt tataaattgg aggaaatata atgacaccta ttatacaatt
    10921 taaaaatatt aaaaaacaat ataatgataa aactataata gataatctta atttagatat
    10981 agaaaaagga gagtttttga ctgtaattgg ttcgtctggt tctggtaaga caacactctt
    11041 aaaaatgatt aatggtctga ttttgccaga tggaggaaat attttgataa accaaacaga
    11101 tatcaaaaac gaggacttaa ttaaattaag aagaagaata ggatattgtg tacagggaag
    11161 tgttcttttt cctcatatga ctgttgaaga aaatatttca tatgtaccaa atctcctaag
    11221 taaaaagaat aaattagaag taaaaagtgc tgtaaacaag tggatggaaa tagtgggatt
    11281 gccaaatgat atgaaagtgc gttacccatc agaattgtca ggtggtcagc aacaacgtgt
    11341 agggattgca agagctttag cttcttctcc agaaatttta ttaatggatg aaccttttgg
    11401 tgcagttgat gagattacac gaaagcaatt acaaaaagag ataaaagaaa ttcataaaaa
    11461 aacaggagtt acgattatct ttattacgca tgatatttat gaagctttga ttttgggaac
    11521 aaagactttg gtattaaatc atggagttgt tcaacagtat gatactcctg agaatatttt
    11581 aaatactcct gctaaccaat ttgtagacca gttattgaat ataagaaaat ctataataga
    11641 tgatgataat ttaaaagaat aaatttaaat ttaaaatcaa attgttgtga taaaaactat
    11701 tgatttagag ctaacttcaa gttgtatact tgaagtggaa aagttagatt aaggtataga
    11761 agggcattta gcagttggct gtagacgagg taactgctga aggtgctttc aataaatggc
    11821 tagaacctgt atctgttgaa gattataata aattgaaata agaagctcaa tatacagagt
    11881 agataggcac ttcaaataga agtgtctttt gtgtgccata aaataaatca aaatattagc
    11941 aaagaatgtg aaaaacaaaa taaaataata tgctatcttt aaaataggag ggatgctata
    12001 tggataacaa tttgattacc attgaaaaaa ctttagatta tatagaaaaa catcttttag
    12061 atgagatgtt agatttaaat gtaatttcta aagagatagg ctattcaaaa taccatttac
    12121 atagaatgtt tacatcagtt gtcggattta gtgtacataa ttatatacaa agacgtagac
    12181 ttactgaagc agcgagaatg ctaattttta cagaaaaacc aattattgag attgctttaa
    12241 tctcggggta tgatacacaa cgctcttttt caagagggtt taaaaaaatg tttaaacgta
    12301 gtcctaattt ttttagaaga catcaagatt ttttaccact acaattaaaa tttgatattc
    12361 ataatagaaa aaaattacgt ggagatatgg ttttagatgt taaaaaagtt aattgtgcag
    12421 atataaatat tgttggctat tctggtaaag taagaaaagg atttcatatt attggaaaat
    12481 gctggaggga tttgcataaa aataaagaga tgatagaaaa taaggtagat ttaggttttt
    12541 taattggagt tagtgattat agcaatttta aagagattga gaatactcct acatttacat
    12601 acattgcagg tgctcaagta gctacttttg gcaaattacc taatggaatg gaaaaattcg
    12661 tattaccgaa aagtaattat attgttttta cttttattgg gaaaaatgag gatagtatgc
    12721 aaaatgttgt agaatatatc tatcaagaat ggttccctaa ttcaagttgc cagtttaatg
    12781 aaaataattt atatgacttt gtaaaatatg gagaaaaaac tgatgagaat ggtttgagtg
    12841 aaattcagtt ttgggttcca atcatttaaa agaaggtatt atgtataaag tagatggatt
    12901 tatataggca aagttttaca gcagtatgta tttataaata atttatagtt tgtaggaaag
    12961 aaataatttt actataagat tatgataaaa tacacaatac tatgacaaaa tagtgttaaa
    13021 taatagattt aattttgcat aggaaaagtt ctataatggt gtgtattcat aaataattta
    13081 taatctgtag gaaagaaata gttttactat aagattatga taaaatacac aatactatga
    13141 taaaatagta ctaaataata gatttaattt tgcaaaggat aaggtgtttt aataaaaatg
    13201 aatgtagaaa acgaattact taaaaaccta gatagattgc atacaacaga gttaggcgtt
    13261 gtaagaatta agaaaaatct ttctttggag acaaatgatg tagtgaactg gtgtaaaact
    13321 aaaatagaat ctccaaatgc cattattaat agaaagggaa aaaactggta tataagtgta
    13381 tatgattgta ttataacagt aaacgctcac agttatacaa ttattacagc tcataaagaa
    13441 aagaaatgaa ttgcaaaata caaaggtcaa aagcattttc cactgtttgt agtacctatg
    13501 aagaagtata taaaataata ttacttttga ataataattt aaattttgga ggttgaaaaa
    13561 atgaatgata ctgtaaaaga aaaattggca gagtcactaa cttctgatac tactgatatt
    13621 ttaccttatt tgccttattt attacaagat ttttgggaat taggaagttc accagaacaa
    13681 atgttacaat tatttagaaa gcatatacct tttaatgagg atacaaaagt tttggattta
    13741 gcttgtggaa aaggtgctgt atctgtgaag cttgcaaaag agttgaatat acatatcaaa
    13801 ggtattgatt tgatacctga atttattaat tatgctagaa gaaaggctat tgaatataag
    13861 gttgatgctt tgtgtgattt tgaaatgaat gatgctaata gttctgtaaa aattgagcat
    13921 gattatgatt gtgtgatttt tggagctgta ggggatattt taggtaatta taaagaaact
    13981 ataagtaagc tattacctac aataaaaagt aaggggttca ttttaattga tgatgcatat
    14041 gtagtagata aatctacaaa tgaacagctt aattttgaga gggtgtatcc cacttacaat
    14101 gagtggtgta tattgttcaa agaattaggt ctgaagctaa ttgaatgtat accatgttta
    14161 gaacttgaaa atgatgttga agaggaaatg aattggatta taactcgtgc aaatgagcta
    14221 attaaaaaat atccttctca aaaagatatg tttgaacaat atgttattag ccaaaaaaat
    14281 gaatatactg atttacagca ggaccttgtt ggagcaactt ggattttaca aaaagaataa
    14341 gataaatatt agactagata atcaatgtta tagtgaatta tcccatgtct agtgaatata
    14401 aataacataa aaaaccgtca agatgaatag tttattcgtg cttgacggtt tttagtattt
    14461 gttgaagtaa aattttattt ctttagtata tcacttttag tcaatccatt tgatttagct
    14521 tgagtattcc attgatgatt ccccataagt ttatatagga atctagggaa gttaggtgaa
    14581 ataaaaatag tacttttgtt ggaatcatct atatgtatat tatcactaag tatatttttt
    14641 gaaagttctt ttaatgcaat tcctaaatct tttttaggtc ctttacccaa aggtacggat
    14701 tctagtgaac caaacatctc cccagctcca attccaatac cttgaaccca tgtaaagttg
    14761 atttttttac accaatgctc tatcatttga attgccaaat gattatgttc accttcattg
    14821 aatccacagt taactattgc atacactgga ataggttttt tattttgtgt ttttaaaaat
    14881 ttttcacatt tctctaaaaa atgaagtaaa tgagatggaa taccatctac ataaagagga
    14941 gatgcgatta ttaatctatc acaattaagt atggcattaa gagcgtcagg atacttagat
    15001 gtgctatcta ctttaaatgt aaaaacttta ttatcatttt gaataagttg ttttaattca
    15061 gataaaaaat actgtgaatt atttttattt acttttggac taccatttat cattactata
    15121 ttcatatgga ttcacctctt atatcttgta tattttcata gaaacaaaca gagtgttctt
    15181 ttatattgaa atttatagca tttccattta ctaatttcgt agcagtttct ttttcagctt
    15241 ctgtaataca atctccatag aatatagctt ttaaatttat ctgtttatca tatctgcttt
    15301 tatgacgcat catattatct tttattacaa agtatggaag aatataatta atgcttttat
    15361 caagtacgtt tttgacaaaa gggctaaacc ctccgtaaca gcatctgctt attataataa
    15421 ttccatcaga gtcatttata agtttaccca tgttgctgta ataatctttt acaacacatt
    15481 cagaaggagt tttaatccag caaccaaaac aaccaataca tttgtggatt tcttttgtgt
    15541 ttggaagtat ttttatattg tcatcaagtt tgggtaataa cttttctaat tctttgtcag
    15601 ttaaatcatg tattaaaagc ctcataaagt ccatctcctt ttattatgta tgtttacttc
    15661 taaaaattat atcttataga tttttcagta aatctttaca ccaattaata acaaaattat
    15721 aatagtcaac tccataaatc attgttgcat acatatatgt atattggtca acgcaatgat
    15781 tttcttctgc atcatttttt tgtttactta atttatttag aagtaattct acttcagtta
    15841 ttaacatttt taagtttgtt tcaattattt ctttgggtag atacttgtaa aagaatatat
    15901 taacaaggtg gtcttgcttt gttttagaaa aatttatagg tttctttaac cattcaagaa
    15961 atacttcttt accagtatta gttatggaat ataatttttt taatttgcta ccatctataa
    16021 cttcgtgata gtgtatatat ccttttgttt ctaatctttt aagtgcagga tagatacttc
    16081 caaagctggc gtcaaaaaag tacgaggtac tttctgacat tatttgtttt aagtcgtatc
    16141 cacttaattc tttttccatt aaaaatccta aaataatgta ttctaacata ttacctcctg
    16201 gtatcaatta gatatatatc gattcgatat atttattatt acagataata aatcttacgt
    16261 caagatgctt tttaagataa gctaaaaaga attaggagtt attgataaat atgcaaaaaa
    16321 attaatataa aaggtaatta aatatcaatg aagatttaaa aatagttaaa tcaaagtaag
    16381 agtctaatat ataaaattta tagtaacttt atggtttaaa tataaacttg cgtgctattg
    16441 acaaagtata aaattagcag taaaataatt gcatgagcaa atagattatt gcgaacgcaa
    16501 aaaaataagg acaatagata ttaaaggaga gaatatgaga gagctattaa aatgggtttc
    16561 cattataaat agatacaata caaattatat tgacaggaaa ttggcggata ttggaatcaa
    16621 taatagccaa tatttttatg tattacacat atgtaataat ccaggtatta cacaggacac
    16681 tatatttgag aaaattcttg tgaatcctag taatataaca agagctttgg caaatttaga
    16741 aaaagaaggc tttataacaa gagaaccagg tgtaaaggat aaaagaacat ggcatttata
    16801 tcctacagaa aaatctttag gatgttatga tgaaatacta aaaataacaa atgggtatgt
    16861 tgaggagttg ttgagttcat ttgagaaaga agagcaagag ttgtttatgt caatgttaaa
    16921 gaaagttgca tttttggcta ttgatatgaa tgaagaagca aaattggagg cgaaggaaaa
    16981 tggaagaaaa atataaggag ccattggaat atgaaaaggt ttcaaagtta ttaactaagt
    17041 acgcaattcc tagtattata gcaatgttag taagtgcttt atataacatt gttgaccaaa
    17101 tatttattgg gcaaggtgtt ggtgtattgg gtaatgctgc tacaaatgtc acttttccac
    17161 taacaacaat atgtactgca attgcattat tgttaggaat tggaggagcg tctaagtgtt
    17221 cattggaatt aggtgctaaa aattcagaaa aagctacaaa agcagcagga aattctatat
    17281 gcttgatggc tgtttttgga ataagtttat ttatagtagt atcaatattt ttaacaccac
    17341 tattaaaatt ctttggctct acatcagaaa tactacctta tgcacacaca tatacaaaaa
    17401 ttacatcaat tggattacca tttcttataa tgtccactgg aatgagtaag ttgatacttg
    17461 cagatgggag accaaaagct tctatgtttt gtatgttaat aggagcagtt attaatacaa
    17521 ttttgaatcc attattcatt tttgttttta atatgggaat tgctgggtct gctttagcaa
    17581 ctgttattgg gcaacttata tcttttggaa taagtgttca ttatataaag aattttcaac
    17641 atattaaatt acataagaaa agttttaaat tagatagtat aatttataaa catatatttg
    17701 cgctaggttc aagctcatgt tttaatcaat tagcaatgac tgtaacacag atagttatga
    17761 ataatacatt ggcatattat ggggctaggt cagtttatgg aagtgagatt ccacttgctt
    17821 gtgtcggtat cattattaaa gtaaatatga tttttatatc tataattatt ggtatatcac
    17881 aaggtatgca accaattata gggtataatt atggggctga aaagtataat cgtgtaaaag
    17941 aagcatataa gtttgcagtg ggaagtgcaa ctattatatc tgttattgca ttcttatgtt
    18001 tccaattctt cccaagacaa attacgtcta tatttggtaa cggaaatgag acttatttta
    18061 tatttgcaga acattatttt agaactttct tgttcttaac atttataaat ggtgttcaaa
    18121 tagtatcatc aactttcttt acatcaattg ggaaatcagt gttgggactt tttacttctt
    18181 tgactcgtca aattttattt ttaattccat tgatagtaat tttaccaatg tttatgggaa
    18241 ttgatggagt aatgtttgca ggaccaatag cagatgcagc agcggcaatg gtatgtatat
    18301 actttgcagt tcatgaaatg aaatcattga ctataaagca aaataatttg atgagtaacc
    18361 ataataagat tgcagaggta taagacaata tttaagaagt atagaaaatt aatttaaaaa
    18421 atataataaa ttaatttagg aagtgtagaa aattaatcta aagaagtata ataaactaat
    18481 ttaggaagta tagaaaatta atctaaagaa gtgtaataaa ctaatttagg aagtatagaa
    18541 aattaattta aagaagtata ataaactaat ttaagaaata tagaaaatta atttaaagaa
    18601 atacaataca ttaattttta agtaacatta aattaatgta agtaaaataa tgttcatatg
    18661 aatatttaaa ggtgcatttt ctgaagctaa gtatatgttg tagagtgtta tgtctctcta
    18721 tcctgtgaag tttaatagct caagaaaatg cactatttat gatgattatt ttgttttatt
    18781 tccaattttg gaaataacta ttctaattaa atctaaaatt ataccataaa taagaaaaga
    18841 aagtatagat gctatgtacc aataaatcga aattgaccct gtaattgttc tacatgggat
    18901 ttgcatacct gaatccataa aaacaaaaaa actatcaact ctggaaataa tagacaaaat
    18961 aggatttaaa cctattagaa caatactttt tgagtcttga ccaatttgat gcatataaat
    19021 ctcaaataat gcaattaaaa aaaaccaaga tgtaaaagat ttaataattt ttttcatcaa
    19081 aatacctcac ataatataaa ttctgtttgc actatttgct tactacaact atttatctcc
    19141 attcagtcac atcacttaat tgtaatctag gtcttcttga tggttcttca tcaggataac
    19201 ctaaagatat tgctgccact aattgactat ctgtatttaa ccattcacat aattcacgat
    19261 atgcaaagta tacatcacaa atccaaagac tacctagacc taattccaca gctgtaagcg
    19321 acatattctg aattgcagct ccaattgatt gcatatttgc catttcatag aatcgttctt
    19381 caggggatag cttttctaaa ggtgatttac ctaatatatt taaaataaaa attgttactg
    19441 gagcttgttt catgatttca actgtgtaat ttgcaccagc gatatgttga cgacttcctg
    19501 gaagaagccc attatcatta atttcatttt gaataccttt gctcatggct ttaagcatag
    19561 attctttttc cttttcagtg atgacaacaa aacgccatgg ttgcctgttt ttagatgaag
    19621 gtgcatttat tccagcttca attattttct ctatagtttc atgtgaaatg ctttgatttt
    19681 tatattttct gatacttcgt ctttttgata tagaatcact tatcatttta agtaacctcc
    19741 gtttattttt tggaaaaatc tatttaattt ttattttcta ttttaattat tttagcatta
    19801 atcagaaaaa aagtcattga ttttagtata caattattaa tgattatatt aagaattgta
    19861 tcaaaaagta tgtgattata ctaagggatt atattaaaca ttatatttaa aattgtatga
    19921 aaggttgtat ttaatattat attgagagat atatatatta ggatttatat atattcagat
    19981 ttattattat attgagtctt atattaaatt aaggactata atttgaaaat aagctataaa
    20041 aactcaatat tgttttgttc aaagataaaa aaagaatact ttaggtgatt tttattaaaa
    20101 attaagagtg ataagattat atactttata aatgtaaata tgacggataa aaatgataaa
    20161 tataataata tatatattta cattaggagt tttctatact ataattattt aaaactaaat
    20221 ataaatgttg gaattattta ggacttgaaa ttgtctaaaa ataaatataa gtgatgaaga
    20281 ggtgatgtga tgagattaga tatggatagt atgttatatg tactaattta tatgacatta
    20341 ttggtatcta tcattggaag tatattttat ttttgtaaag acctcttaaa tcataaaatt
    20401 aagtatgttt taataagaga catatttgta aatagaatta catattctga agaacggttg
    20461 cctaaacagt atatagtttt tcagaaatat gatatttgga ggtattgtag tttgttttaa
    20521 tttgaaatga atctattata aattctaaag tttaaaaata aaaaggagag aataaaatgg
    20581 atttcatttc aagtatattg caaggattat taagtatatt atttaatttt acaggtgatt
    20641 ttggaatttc tattgtactt ataactttaa tagttaaatt agtacttatg ccactatcat
    20701 taaaacaaag attttctgta aaaaaacagc aagaattagc tgaaaaaatg gaacatataa
    20761 aagaaaagta taagaatgat actaaagaat tggaaaagca aatacaagta agttctgtag
    20821 aaagtatgaa gagtatgctg ggatgtctta tagttttggt tcaaatgcca gtagtatatg
    20881 ctttatatca tgtatgttta gatatgacaa aggaatttac aacaattata attccatgga
    20941 ttgctaattt aggtacattt gataatttgt ttatattacc ttgtatatat acattaatta
    21001 tgttagcttc aaatttagtg aattatatac catatttaaa aataaattct caagtaaagt
    21061 ttaacaaaca aatggctgtg gtgactacca taacaagtct tatactaact gttagaactc
    21121 cagtagccat aggtctgtac tttataacaa gtgcaattta ttcattaatt gaagatattt
    21181 gttttagaat atattttaat cgaaaaaata gaatagtgac aaaataatat aattattatt
    21241 agaaatattt tagcctgcta acatagaaaa agttagtagg ctatttttat ctatgatatc
    21301 aattccatta agaatagtct aaaaaatact atcaaaatgc tataaaaaat actatcaaaa
    21361 tactataaaa aaatagttga aaaataaata aattaatata aactaaaata aagcctacaa
    21421 aaaagaggtg ataaatagaa atggctaaaa tactaattgt agaagatgaa aaaaggatgc
    21481 aaagtattat tgtagaatat atgcaaaagg gaggatatac ttgtataact gctgatgatg
    21541 gagtcgaggc acttacaata ttaaagagca acaatataga tttaatgata ttggatatta
    21601 tgatgccgta tttagatgga ttttcagtgt gtagagtttc acgtgaaatg actaatatac
    21661 ctattattat attgacagct aaaggtgaag aggaggacaa attaaagggt tatgaatatg
    21721 gcgcagatga ttatataaca aaaccattta gccccaaagt acttttagca aaagttaatg
    21781 ccttgttacg tagatacact actgatattc ccaaaaattc attgagttta ggaaagattt
    21841 ttattatggt agcatcaagg caagtgtatg tagaagataa attgattgat ttaacatata
    21901 aagaatttga attattgcgt ttatttatgg aaaaccctaa tcaagttttt tccagagaga
    21961 aacttttaaa ttgtatatgg ggatatgatt ttgaaggaaa cacacgaact gtagatacac
    22021 atataaaaac cttacgcaaa aagcttggta gtgaaggaca ccatatagtt acattaattc
    22081 gttcaggata taagtttgag gttaaggaat gaatagttta agaaagatta tagaaaaact
    22141 gaaaaatgta gatatttcaa attggattaa acaaaatttt ggactatatt cagttagaaa
    22201 aaaagtgttt ttactttcta aattatcagg agcgttaatt atattatttt atctggttgt
    22261 tgaagaattt tcgataaact ctaaattaga attttggatt tggtttataa tactggttat
    22321 atttattatg agtattgatt tcttattggg aaaatttatt tcagaaccaa tcacatctat
    22381 aaataaatct gcaaaaagta tgtcccaact tgatttttct aatccatgta ctgtaaatac
    22441 taatgatgaa tttggagaac tttctaggag cctgaataca atgtctacaa atctacaaca
    22501 ggcattatca gacctagaaa gtgcaaatat tcaacttgaa aaggatgtaa ataaggaaag
    22561 aatgctattg gaacaaagaa aggagttggt agatacaatt tcacatgaaa tgaagactcc
    22621 acttggcatt atacgtgcgt atacagaggg gcttatggat gaagttgatg aagaaaaaaa
    22681 gaaaaattat atgaatgtta taatagaaga aactgataga atgaacaata tgattgtatc
    22741 attattagac ttatctgcat tggaagcagg agtttctaaa cttaacccag agcgttttga
    22801 ttttatagag tttgttgaaa ctgtggcagg tcgtctttta attgatatac cagatgccaa
    22861 tttttatttt acatatgatt tgccagagta tgaagttttt gtagtggcag ataaaatgag
    22921 aatggaacaa gtagtagaga atctagttat taatgcaaag aagcatgttg tatataatgg
    22981 taatttagat ttatcgatta catgtgaaaa tggcttgctt ttatttgaaa tttataatga
    23041 tggtaggttt atagagcaag atgagatttc aaagatttgg tctaagtttt atcgtagtgt
    23101 tcaatctcag cgtacaggag gttcaggtct agggcttgca attgtttcac aaatacttac
    23161 aatgcaaggg ttagaatatg gagtgaataa tcgtgataga ggagtagagt tttattttat
    23221 gattccaatt gatgaataat ttagtattaa tttataaatt ataagtatct gatgtaaaat
    23281 atttttcttt gtatatgtaa gcatttaaag agaataaaat aaaaaaactt aatgaaaaaa
    23341 gcttaatgaa aaagtctaat aaaaagctta atgaaaagtc ttgtttttct gatgaaaaca
    23401 agatttttta ttaagctttt tattatttca cttcgatttc acaagagaga cactctgatt
    23461 tcaccaaata gaaataaaat aggttaaata aattaaaaaa tagaagcgta attaaataag
    23521 gttacaaggg ggagtactta tgaaatggta tacatggttg actattatat tgataatatt
    23581 gctttctatt ccgcttaaaa ttaaatttat aaaatggtgg gatagacgac aaaaaaatga
    23641 taaaggaggt tatgatagat gataaaagta ggagagttaa aattttctta tggaaaagat
    23701 aaacagatat tgcatggact taattttgaa gtaaaagaag gagaaatctt tggattcctt
    23761 ggacctaatg gttcaggaaa atccacaaca cagaaaatct taaatggtgt tttaaaaggt
    23821 tacaatggtc acgtatccct ttttggtaag gaagttaaag catacacaga atctttatat
    23881 caaaagattg gtgttttatt tgaatttcct tatttatata ccaatttaag tgcaattgat
    23941 aatttagaat atttttcgtc tttttatcct aaaaatcaaa ggagagatat atatgaactc
    24001 ttagatttgt tagagtttaa gaaagagttt ataaataagc ctgtatcatc ctactcaaaa
    24061 ggtatgaagc aacgtattag tatggcaaga gcattggtaa gtaatccaaa gttgttattt
    24121 ttagatgagc ctactagtgg acttgaccca tctggagctg tactatttcg taagattatt
    24181 gaagaagaac gaaaaaaagg aacaactatc tttttgacta ctcataatat gctagatgca
    24241 gatttaatgt gtaacaatgt ggcttttatt gcagatggaa agattatggt aatagataaa
    24301 cccaaaaatt taaaaatgaa aaatagcaat aataaagttg aagtggaatt tgtatataat
    24361 ggaaatcgag atattgaaat tgtagatata caagagttag aatctggaat aacttttaaa
    24421 tatgatgaaa tcttaagtgt acattcaaaa gaacctacac tagaagaagt ttttattaaa
    24481 tacacaggaa ggatgttagt gtaatgtact ctaaattttt taccttagta aaaaaagatt
    24541 tttggatgat gatttatggt aaattttttg tgctgacact tggctctctc atactttatt
    24601 cgtgttatat taattttggt tatgtaaagt ttatggatga agatagttat cacaataatg
    24661 tatatctata taatccagag aatataagca tgagtgcatc tccattaatt aatcaagttt
    24721 cttctatagg tgaattaaaa gcaaaacttg atgaagatac aagtgcagtt tgtattgata
    24781 tgagttccag taagccgaaa gtaattttac atgaaagtat taaaggagtt gacgattata
    24841 gagctgacta tgcattgtca ttattatcat cagaaaaaga ccacaatagc aaaatatcag
    24901 acaacaatgc aataattcaa attaatgata aggatacatc tgagataaaa caaagaaaag
    24961 acatgacttg tgagatttta ttctttgaaa ttgtagctat tggattttta gggattgcct
    25021 ctttattatt taaagaaaag cagatgggag taatgcgtat tactggtatt ttacctgtaa
    25081 aaagaagtct ttttatatta tcaaagatat ttgctttttt gatatgtgac ctatgtttta
    25141 cagttctttt agtagtattt aatattggat tttttgaagg aataaaaata cttccacaag
    25201 tattagttca agctagtatt ttatcaatta ttatgtcttt gattggaata ggatgctcaa
    25261 tgttattgag agattttaag caattttctc ttatatatct tgtggttgct gtattcataa
    25321 ctacacctat atttctatct gcaaatacat cttttgaaat agattggatt aaatatcatc
    25381 ccttctatca tgtttatagt cagcttaaaa atgcgttttt catgaatttt tcaaaagaat
    25441 tagtttattt tgtagtgtgt tctttgacaa taatagttct atttttactt gtaaaatata
    25501 tttttaataa agagttggtt agggagggat aatcttgata ggattacgtt accagttaaa
    25561 gagtataaaa aaagataaaa tgtgtataat ttccttcttt ttaccagttg ttatggcgat
    25621 tttaataaat tttatgggaa caattgatat atcttcatta ggagagatac gttttggtat
    25681 agtgaaggat acacttcctg tacaaacaga gcagtggttg aagaagtatg gtatggtaag
    25741 tgtatatgac acaaaaatgc atttaatacg tgaaattaag gatattaaaa cagacacaat
    25801 tggagttgtt agagatggta aagggataaa aactgtgctt tatggaaatg agattaatgc
    25861 tataaaaaat gttggaaaga cattgccaga gatgtttaga ctaaagggtg atttaaaaga
    25921 tgttgaggtt acaatattgc ctaaagatag tattttaaaa gagtttcaaa atgtttttat
    25981 tgccatgatt ttaattactg ctatgtttat gggatgcacc tttaatgcaa tgaatattat
    26041 atctgaaaaa gaagatggaa tatcatttat aaatgaagtt ttgccacaga gtagaagtca
    26101 gtatattata caaaaagtat ttttgggtct tttatgtggg tgtttatctt caatgataac
    26161 tgtatttata tgtttggata tttcaatatt agatatgata atgatgttgt tactcgttgt
    26221 attttcagca tttatttcat cacttatagg tttatttatt ggaaagttgt cagaaggtct
    26281 tatggtagga attgtttata ttaaaatagt aatgatttta tttataggta ctcctttgtt
    26341 aatatatctt ctaggggtta ataccagtgg tatagggaat ttatactata taatgccttc
    26401 agttgctaca tttaatggta ttatggagat tattaatggt aatgtcatta ttatcaaaga
    26461 tattgtaatt ttggctgtac attgtgtagt atggtttatg atatatatta ttttagataa
    26521 aaaaagaaag ttatttttta gtagataact cagtataatt ataattggga caatttaata
    26581 ggtgatttaa tatactttgt atagtgtaat ttatgtagtg caatttgtat actttaattt
    26641 atgtagtgta atagttagtt ttattttata attattcaat ataatttagt aagaagttca
    26701 gtacaattag agctacttag tggaaaactt aataggtact taaactatat aaatacttta
    26761 ttttcctcca tttgtactat aaatttaatt tatgatataa atggaggtat tattatatga
    26821 tttgataaat ttcatcatta taacctacaa gtaaaggtat tattatataa agttaataaa
    26881 gatagtatca aaatattatt tgctataaag agaggggctc aaaataaaga taaacctatt
    26941 tttcaatgtt gaaatgataa aatatatttg atttcatata aaaaattttc ttcataaatt
    27001 aaaaagtcca ttttaagccc cctcattttt aaccagataa atcgagttaa actatttaaa
    27061 tatattactc ggattcattt gacttagata ttccttgctt gtaaaattgt tttgaatagg
    27121 ggatagccaa agcaaaaaat aaaagtataa tccctgctat gattattaaa ttattaatag
    27181 aaattacatc tgccattggt ccgaaaatca tcataccaag aggaataaaa ccagtatata
    27241 taataatagg taagctaaga actcgaccta gcatttgtgg tgctacatgc tcttgcaaca
    27301 tagtcatagc tgatgcttga atgattggaa ttgaaaaatt cgtaaaaaac ataaatataa
    27361 aaaattgcca agcttgtgtt acaagaccta gaataattga aaaaatagca taggataata
    27421 ttgctagaaa aaaggtctta tttctatttt taaaaccacc aaaaactcct ataatcaatc
    27481 cacctaaaac catacctaaa aatccaatca tttcaataat agacaggtat atataaccct
    27541 tgccaaatgt tcgttcaata agaagtccta taagaaatcc tgatggaaca caaagaagca
    27601 tgaatgctcc ataagtaaaa agcacttttc taatgaactt atctgaaaaa cagtacttta
    27661 tccctgatac catatctgca aaaaatgaga ctttttcagt ttgttttggt atatcatgtt
    27721 taggaatttt gatgaatatc aataatacaa tagcaataat tgcagtaaat acatcaatta
    27781 aaagaacttg atttatttta ttaccaaatc caagtattgc agcagctaca ataggaacta
    27841 taaattgtac tatagattgt aggctactat ttataccatt aaaacgcatt aaatgttctt
    27901 ctggtacaag ttgaggaatc attgcgttta cagcaggtgt ttgtacacca cttcctagtg
    27961 aacgtataac agatattact gatatggcta ttaattcact tgttgtgcca tttgatgaca
    28021 tcataaatag aattagaact aatgtagata tagcaattgt tgaatctgat acaattatga
    28081 gtacctttcg attgtagtag tctgcccata caccagcaaa aaaagaaatt atcatttgag
    28141 gtataaagga gcatacagtt aaaactgtta cccatacacc tgatgatgtc tgaagtgtga
    28201 cataccatat cattgccatt tgtacaagtg atgagccaaa taaggaaata tattgacttg
    28261 ctaaaaaaag aatgactttt ttcttccatg tagaattagt atttttgttt tccatcctat
    28321 tcctcctttg atttgtgtgt tgaatttttc ttgctcttaa ggataacaca caaatcaaag
    28381 tctggagtta gagtggaggg ctaggaaaat tgttttttca taatttgaag atgagatttc
    28441 atggtttttg cattatgttc agcttctttc aatgaagtta tcagtttgtc acacactgag
    28501 ataatttcgt catcatcttt tggagtgtca aggacagttt taatattagt attaggatta
    28561 gaagataaag catttaacat tcgtaaaata gctgaaagag aatagtttgc acaacgaagt
    28621 gcgcttataa ttttaagtcg ttttatatct tcatcagtat atacacgata accattttgt
    28681 tttcttttta cttttaacaa accattcatt tcccaatttc ttaaagtatc tattgtaacg
    28741 tttaagtgtt ctgcagtttc ttttctagtt aaaaagagtt tatttgtttc tggagtattt
    28801 ccatttaaaa tctgtgcaac aatagtaagt gcttcctcgg cattagattt ttctatttct
    28861 aattgttgca agtattgatt tacaagacta atagccttat caaagtccct attcgctgat
    28921 gttcttacaa tctcaagggc atcttttctt aatccccttt gtaccacttc aattttcaag
    28981 gctgtacgag caaatctaaa ttgttctata tgaaaatcat taaagatacg ataaccattg
    29041 gtattacgct taggtttagg tattaagttt agttcttcat ataaacgtac tgtattagga
    29101 tgtacaccaa ttaaatctgc tacctctgat gtcgtgtaag tgtccattag tattcaactc
    29161 cttttagata tatagtatta gtcataataa caccaaacaa aagtctggtg ttataatgga
    29221 gggtttggtt atctaagagt aattaattta tgaaagagta attaatctat tatagaagta
    29281 agtatatatt tttcaataaa ctcccatcta tcacgaggtt taaacactat tttagatggt
    29341 atggctatta ctaagtcata ttgtggaata caacaaatag catttcctcc agctcccatt
    29401 gctgaatacc acaaaacacc atctttttta catagccacc acagataacc gtattcatta
    29461 ctattcattt taactgattc ttcaatccac gatttagata taatacgttt attattccaa
    29521 ataccatcat ttaaatacag aaaaccaaat cgcaacatat ctctagcact caatgtaagt
    29581 ccccagccac ctatagaata accctgtcta tcttttgccc aacccttaag attttttcca
    29641 aagaaatctt caaaaccaaa atctttcata tcataatctg gtataacttt cataccaata
    29701 ggtttaaata agtattcatt agcaaattca cgagcagatt ttccagtagt ttttgttata
    29761 atagctgaaa gtaggtgcgt tccagctgaa gaatatttga aagtaccaat ttcgcctttt
    29821 tgaccaagtt gattcaaggt atattttatc caatcttttt gtttgcaaag tctttctaaa
    29881 gactcagtca tatttttaaa agggtatggt gcagtcattg taagtaggtg acgtatagtt
    29941 actgcttttt tacatatttc agaaggacta taagtatatt cagggaaaaa atcaacaacc
    30001 ttttggtcaa catcttttat atatccttta tctattgcaa tacctattaa ggctgatata
    30061 atactttttg taactgatgc aacatgaaaa gtatcatcag cattatatcc attatagtac
    30121 ttttcaaaga caacttttcc ttttcttgca ataattattc catttatatt actatattgt
    30181 gagattatta aaggttcaag ttgtgagagt ttttctgaac tcatgccaac acttgaagga
    30241 tttacttttt caaatattaa atctaagcaa ttgtttttat tcattaaaga tacctccctg
    30301 ttatagattt tggattttct tttagagttt ttggagaacc ttctgcaatt atataacctc
    30361 ctttgtcacc accttctgga ccaagctcaa caatccagtc acaaacattt aatacatcta
    30421 tatcatgttc aacaacaatt acagaatttc cattttcaac caattcatct aataattgaa
    30481 tcaacttaga agtatcgtat agacttagac cagtagttgg ctcatccaat acataaagga
    30541 tattaccatt tcgtttttta ccaatttctt ttgcaagttt gattctttgg gattcaccac
    30601 cacttaaagt tggtgtaggt tggcctaatt ttatataccc catacctatt tgttctaata
    30661 catttaagtg tgaaacaata tttggaatat ccttgaagaa atgtacagat tcagaaacac
    30721 tcatatttaa aatatcatgt atatttttat ttttatattt aatagataaa gattcatcat
    30781 taaatctttt tccctgacat tcactgcata tatggtctat acttagatta tttcccaacc
    30841 agaccttttc atatccacta ccactacatt taggacaagc ccctttggag ttaaatgaga
    30901 aatgaccagc tgtaaatcct cgttctaacg attctggctg acctgcaaat agtgtacgta
    30961 tcttatccca tataccaata taagaagcag gagttgagtt catatttttg ccaataggag
    31021 attgagatat ctctgaatat ccagaaatat gtttagtacc aatcagtcta tctgcaatag
    31081 tttcaacaac tgcataatcg tcttcctcac ctatttcact ctctgaagaa tttatttgat
    31141 tattgatagt atggttatta aattggcttc taagaagagg aagtagggtg tctgatataa
    31201 gtgaactctt gccactacct gattttccag atattccaac catagcaccc aaaggtaatg
    31261 atacagttac atttttaaga ttatttgtat ttgcattttg aatagttata caaggtattt
    31321 tatcagtatg tgtaatgttt ttattgcttg ttctattagg cattggatat tttccagata
    31381 gatactgtcc agtgagtgat ttgtcggatt gaagtagacc ttctaaatct ccttgatata
    31441 ctaattgacc accttcaaca ccagcttttg gaccaatatc aataatatgt tctgccattt
    31501 taattgtgtt tttatcatgc tcaactacta tgaccgtatt gcctaaatct ttaagtttct
    31561 ttattgattt taagatgtct attttttctg attcatgcaa tccagctgtt ggttcatcaa
    31621 gcacataaat taatgagtcc atctctgaat cgagatgtga atttaaaaat agtctttgca
    31681 tttccccacc actcaaagtt gacatttctc ggtataagga tagatgacct aatcgtgatt
    31741 ctattaaatg ttgagttttg gataaaatat catttacaag atttgtacca aatgtgttta
    31801 aattaccttg atttattaag agtttaagga aatcatcaat ttctaaaatc gtcatttttc
    31861 caagttctcc aatatgtttt ccgtttaaaa gtactctacg tgcttcttca ccaattttaa
    31921 aaccattgca atctgaacag gcagtcatag tataaactcc atttaaatct tcgccccttt
    31981 tgtaacgatt gtgaaatacc tttgataaag aggaactttt tttaccattt tcataatgac
    32041 catagagtac ttcatttctt acttcttcag gtagttgtaa gaattgtatg tctaaataat
    32101 cattgaattt tttagaaaat actctcaaat atccaggtgt aatctttgct ctatctaaga
    32161 cttgttttag ggtatcatgc ttatcaagga ctaatttttc aatattaatc tcaaaatatg
    32221 caccatgtcc agagcacttc atacacattc catctgaaga gttgtatgag aaataacttg
    32281 gtcttaatcg ttcttcctca tatccacaat tattgcaaat tagattatag cttacaggag
    32341 tatcacacat agtacacatt atttgacctt ccactgaata caatagtgta agcatgttga
    32401 gaatattggt tcttgtgcct actgttgaac gaggattgct ctggcgaata atattttgtt
    32461 gaacagctat agtgggagct aaaccttgaa tattatcaaa cttatcttca ctatcaatac
    32521 ctgcaagtat acctaaagat tgcagatatt gtttacgccc ttcctcaaat acaatgtcaa
    32581 acataaggct agacttacct gagccactga cacctgttgc aacaacaagc ttatctttgg
    32641 ggatagaaac atctatattt ttaagattgt gtatctttgc tccattaatt tttatttctt
    32701 tcattggttc acctcatttt atcaatttta tcaaaccgta aaatagggat atattaatcc
    32761 ttaatacaag aatagattag gtgaggttat taaaaaggtt ctataggtaa atatatatcg
    32821 accaagtgtc tattttgagg gtgattgtgt gggttgttaa gatatacttc aaaagggaag
    32881 gaggcacgta gcttataatt accatttgat agccattcat tatacataaa atcccacgca
    32941 tcactatatt cagattttga aatatcaaaa tgtcccacaa gatattttcc agaaggtatt
    33001 atcatattgc caagattgtc attctctttg acaacaatgt tatctggaat ggtcatgcaa
    33061 atactagtcc ttaattgatg ctcctgtgta aattgtggat tatcatgata aatggctaat
    33121 atttgtgtgt tttcaagtcc aagtagattc tgctcacttg catatgtgaa taaccgttct
    33181 aaaagttttg ggaaagtact ggttagatta ccatatgaac cagtatacct agtgtaaata
    33241 gtattcatat tatcaagttc tagaatttca atttcacctt taacctctct agtattctta
    33301 catttaggtt ttgatatgct tctattgtac tgagaaattt tatatggttc tttgcaattc
    33361 ttgctataat tgtttctata ttttataggg cttattttat agtaattttt aaatgctctt
    33421 gagaaaactg ctgaatcagt aaagccaaag tagtgtgcaa tatcagtaac agtcatgtca
    33481 gttctatgaa taagaaaagc agttgcattt tctagtttta gcctatttac atattgtgcc
    33541 aaagtttctt tttctattgc tttgaagatt ctatgaaaat gaaattttga aaaacctgct
    33601 atattagaaa gttcatcaag agaaagaggt tcatgtaaat gttcttctat atagtcttgc
    33661 actttgcaaa tacgatttag atattctttt ttacttttag catttgtcat atatagccct
    33721 ccttattgtg taaaatgtgt atcaattaat ttatagcaat atagtaataa aattttatgt
    33781 ttttgtaatt tatgataaat aagatagcgt ttaatttttt ataattgata aaagatattt
    33841 ataattaata aaagatataa gatgccttat atttgtcttt gcatataagt atagtcttcg
    33901 taataattag tataccatag tgatttattt ttaattgtgt atttatataa atacacaact
    33961 tatgatatgg acgaattatt atgcaaataa gctgtaatta aataaattgc aatataaacc
    34021 agttgaaaca taagttaggg aaatattatc aaagttatta cttagcataa gagtatagat
    34081 ggaataaaat aagattaaaa aattacatac taaatttaat aaaattttta tattaaaaat
    34141 aatattaagt ttattgttta aataaaaaag ttaaatctac actattaact tattatactt
    34201 aaaactttaa aatgaaaata tcaaagaata ctttttaata aaaataatca tttaataagt
    34261 tatttaaaaa tctaaaaact ttacaacaaa ttatctattt aaattggagg agtgggaata
    34321 tgagtaatag tttttatcaa ttaaattcag cagtattata ttttaatgaa aaaagagatg
    34381 taaatagaat aaggtttaat cactatgtaa tgagaaaaga aaatatacaa agattaaaag
    34441 gaactctgcc aagaggacaa tttatgatga cagtaaggaa agctgcatct gaccttgatg
    34501 tatctatatc tacaataagt agacttgtaa atgaatttat agatttaggt atattgagat
    34561 taataagtag gggagtaaag ggaaattgtt gttctgtata tagttatgtt tgttctgaaa
    34621 gtagtaatgc agaaattgta acaaagaatg gtgatatttt caaaaatata gagaaataca
    34681 ttgatgcaac tattaacaat aaccaaaaaa caatgaaata taaacataga aatgagttgt
    34741 ttaagaacag taataccaac atatacagcc gtataaatca agagagtata gacaaagatt
    34801 atgatttgat aattcatact gggtatgaaa cagaaaatga gacaaagaaa aaagaattat
    34861 taaaaaataa tttaaataaa aagaatttaa ataaaaatac ctttgaaaat tcggatgaag
    34921 atttgactga agattctact tacaaaaatc cagaaagcat acatgaaatt attataagaa
    34981 aattaaatag tgaatcagga aaaaatttta aagctgattt gagtataact aaggcactta
    35041 tagataaaag attaaaagaa gggtatagtt tagaagattt ttacaaggtt atagaggcaa
    35101 aggtaagaag atggagatat acagatatgg aaatatatat agaaccaaca attctgtttg
    35161 ggtatgaatt tgagtcgtat ttaaatgagg agagttcttt atctgcttgt aattatggtg
    35221 atatgtgtta tgaagatatg tattgagata ttagttgctt tttagttgtt taaaatatgt
    35281 ttatatataa atataaatag tgtattaaaa tggagttgtc tcaaaataga gagaagcctc
    35341 ttcttaattg tttaaatgat gaaaatatat ttgatttaat acaaaggaga gtgctttatg
    35401 agttagaaga tttattttga gacactcact ttttttaata tactggagaa atataaccca
    35461 ttttaatagc ttttgtaata gcctcaactg atgatgaaac atctagcttg tcatatatgt
    35521 gttgtaaatg atttgataat gttctttcac ttatatacaa ttcatcagca attatttttc
    35581 tttttttacc actacagata agctgtaaaa ttcttttctc catagtagtt aaatcttcaa
    35641 taattacttc agtattttca gatggaaaac aagttacccc ttgatagact tttaataatg
    35701 aatcaattaa actatcaggg ctaatattct tattgaggaa tccatagata cctatttttt
    35761 tagcctcatg tttataaact gggaggtcgt atccagtcaa gattattatt ttaatagttg
    35821 aattagtctc taataaatta taagctactt ttaagccatc acattcactt aagcctctaa
    35881 ggtttatatc cattaagaca atgtctattt ttttatcttg aatcatttct gaaagattat
    35941 ggatgtcctg tgtggaataa aactgttcga tttctttgta ttcttctagt gcaattgaca
    36001 agcttttagc aaaaagcata tggtcatcaa ctaacaaaat atttataaga accatctcct
    36061 ttcataggga ttgtaatctg tacacaaact ccatgaggta tattatcaga aacacttatc
    36121 gttcctccta gattttctac ttgttcttta attgatataa tccctttgtg ttttattgta
    36181 tcaaaagtaa ttttagttat atctaaaggc gttttaaaag atgtatttgc cacaccatta
    36241 tcactaatat ttaattttat tatatttttt tctagtgcta aagctatcca tgcatggcta
    36301 ccatttgaat gtttatacac atttgtcaat aattctttaa tcagtcgata tatcaatata
    36361 tcatatggtt caactaagaa taaagtatca gaacacttaa atgaaacaca aatatttttt
    36421 tgtggaaagg atgaagaaac actttcaatt aaattctgat aattttcttt tactgttaaa
    36481 ttttttaaaa taacaggatg atagtcttgc atttgcttcc ttatacatgt atttagattg
    36541 ttaagtgttt catatataat atcttgaaca tctgggcgat atgacttact catcatgttt
    36601 tttattgaaa gcaggttctg taatatgtca tcatgtaaaa aattagaaaa ctctgttttt
    36661 agttgttctt cttgttgtaa tttttctaat gcaaaagtat acttgctatt tttaactact
    36721 ttattttttt catctctaag gttaaactcc aaaataatgt tacagaggaa aatgagcata
    36781 aataaaacat ttatagctat taatattata gaaaaattcc cattggcaaa tagtacgacc
    36841 aagctaatta ctaaaatact tataaaaaga aatatagccc tttgttttat gttaaaaact
    36901 gttgaaatag gaaaactatc attttcttta agtgcaatac catgaatact cataaaaaat
    36961 accagtacag ttagatagat tccaaaatta ccaatatgat ttgatattct tagtgtaaaa
    37021 aaataataag taaggaatcc tataattgtt ataaatactg aaatcgatat aggttttttt
    37081 tcgcttttta tgacaaaaac aacccttttc aaatgataaa aaataatata gaaaaagctt
    37141 attatactaa caacaaactg tattccgtac atacaagcat acgttctgtt agaaataaat
    37201 gctcctacaa ttgcaccaat gcaggtgata agcaataaaa tgtctgttat cttacggaaa
    37261 ttgtatccac taccttgaaa caaaaataaa aatataaatt taatagagac atacactata
    37321 actgtgctta atattttaaa aataatagtg cctattggtg tggttacaaa tgataagagt
    37381 aaataccaac tgtctagtgc tagtaatcca caaaacaatg aaataatgtt attttctcgg
    37441 acattacaag aggttatata tgtgatgtct atgagtaata atgttgaaat tattaaggga
    37501 ataatgcttt gaatattcat ataagtttca gtgcttgtag atattcccat gaagagaagt
    37561 gatagaatgt agtttcctaa aaatagtatt tttaaattaa aatttgtcaa tcttatacac
    37621 ctccttatga gttaattata ttaattttat gactaaatca aacttaagaa tttatagttt
    37681 taaattatat caaatactta taaatgaagt ataccaaatc gtcacacctt taagcttgac
    37741 gatttggcaa atattatttt tttaatacaa ttttacaaca ggatttaata gtaagtatgt
    37801 aatatatcaa atatactaca gaagttaaga aaattgcaat aatcacaggt atgtattgtg
    37861 aaagtgaatt tccaagtaaa ttctgcatca aagcagtctt ataaaccaag gtagcaaata
    37921 tacagtccac tataccaagt aaaaacggaa tattaaaaaa tggcaatact tgttttttaa
    37981 taattttttt aatttgtata ttagtataac ccattttctg taaaatttta taatcagatg
    38041 ttgaatctga aattgctgat atattgttaa agtataaaat acttccaaca gcaataaaga
    38101 ataataccac aagaaatccg attaacagaa atgtagaact attaattgat aataaatcat
    38161 ttatcctgtg agaatatcct tgtaaataag ggcttccatc taaataatct gaaatattac
    38221 tatataaatt ttcattattt ttaattgatt taccattaat acttaaaatt cttgtcattg
    38281 gtaatttatt ttgtgctatt tgctcatata tactatcatt aacgataagt gttccaacgc
    38341 tattggcaaa agaaatagca ttgtttaatg atgtttccct tacagctaca ggtgtttctt
    38401 taccattaac aagtaatgga taaatcgttc cattttcact atatccatca ttatttggtt
    38461 gatatttcat taaaatacat tcattatccc ttaaaggggt aagttgtttt agtagctttg
    38521 ttcgattttg tgcctttaat aaagtataat aatcagaaaa agatatacat tcaaatcctg
    38581 attctcttga aataacttct ttagaagaac tactattgga taaattattc ttagatgtac
    38641 caatttcata ttcaaatgga aggtcttttg atgaagattt taccttataa atatttgtct
    38701 gtgtaaaaat aatatcatct gtattagacg tatattgact gacaatttgt tttacatctt
    38761 ctatttgttt atttttttct actctaaatt ctatctctga aggtgcaata cgcgaaacag
    38821 atgcaatagg gtagtataag gacagtgcca taacacttga aactgtcaaa gtagtagcag
    38881 agagtaatgt aagcataatt agagttttag agtttgaacg tatacgatag ataaagtttg
    38941 gaatagctat tatcttcata tctgtgtaga aagtacgttt atttttttta ctattttgca
    39001 taatatatgg aagaaaggaa ttgataaaga gaactgtacc aattacaatg ataatcatag
    39061 ttatcaagcc catttgataa aatccaatac ttacccatac tgatttagct ccacgaagaa
    39121 tatctagtga taaacaatac ccgcttaaaa tcataataaa ccccataaag gctggaattt
    39181 ttctgaactt taattttttt tctgcacttt tttcatatct tatcaatttt acaagtggag
    39241 tcttataaaa aaatttacca tttgatacag ctaagactaa aacaactaat gctataaaga
    39301 taattgtttt atttattgca tttatattaa aaaatggtat ctgtgaatta tcaattgata
    39361 aattaagtag tgctgtaatt ccaaagacaa tacccttatg tgccaatgct cctaatacca
    39421 atccaataat aaaagctcca ctacaaatta atacattttc aaaggtaagt agcgataata
    39481 ttgtaaactt acgatagcca agtaaagcat atatacctaa ttcttttgta cgacgtctca
    39541 agaagaatcg atttgagtat gccatataga agatgacaaa tgccatcaaa aatatcgaaa
    39601 taacattaca catagattca actctaccat cagttgaaat tttttctagc attatcttat
    39661 taacagaaaa tgaagtaaat gcgaaaaata cagtaataac aaaagagact gaaagtagat
    39721 atagagaata gaatgaaaag ttttttttaa gattctttat tgccgtataa aaaatgttca
    39781 ttaaattatc ctcctatctt ttagtatcca attttgcaat ttcttgaata atcaactcat
    39841 aaaatgtatg tctattattc tgttgtttat ttaattcttt aatgatatga ccatctttaa
    39901 aaatcaaaat tctatttgca aaacttgcta cataggcatc atgtgttacc attaaaattg
    39961 ttgttttcaa ctcctcattt gcttcctgta gtgagtggag tagttcagta gctgaattag
    40021 aatccaaagc tcctgttggt tcatctgcaa agagaatact aggatgtttt actattgctc
    40081 taactgctga agctctctgt ctttgcccac cagataattc atttgggtat ttatttaatt
    40141 gagaagctat gccaaatcgt tcagctagac tctttaccat gttttctatt ttatctggat
    40201 tgagtttctg aagtgtaaga ggtactgaaa tattctcgaa aattgtaaga ctatctagta
    40261 aaaaatactc ttgaaagata aagcctaaat tatccttacg aaaatcagca gcacaagtgt
    40321 cattaagcga tttcaaattt atattattta tgaaaatatc tccacttgtt ggtttatcaa
    40381 ttgtagataa tacattaagt agagttgttt tcccagagcc agaagctccc attataccta
    40441 taaattcacc ttctgataca ttaaaggata ccttatctaa actcggctgt tgccctttat
    40501 tataagtttt agttatgtta tttactttta atattgtatt cattgtatat gtctcctttc
    40561 gtcttaatat agtcaaatta tatattaacc ttattgtttc ttcatgagta aatcacgcaa
    40621 taattctaca caaattactt atatcacaat atattgttta aaatctaact ttattaggtt
    40681 tgggatgatg gacaagattt taatttaaaa gagtgcatag gtatatataa tggcataatg
    40741 tggatttaaa ttaaaaaaaa taaaataaag ccataaatat tgaaattttc aatatttatg
    40801 gctttattgc ttgtaataat taatagaata tatatttttt attaatcatc tatttcaaat
    40861 tctaatattt taccagtaat tgcattaatt gttatctcat attcagtttt tccttttatt
    40921 atttcacctt catattcttt gtcatcttca tcatacttaa attttactat tttcccacca
    40981 ggcactttat ctagcattat tgatttagct ttttcagcac taataataga actgttgtca
    41041 ttagtattag agttattctt atcattatca tcaaagtcat catcagaatc attgtccatg
    41101 tcaatatcta caattcttcc atcaaatgca cttatctcta attcatatgt tttcttattt
    41161 tttattactt tagcctcata ttcgttatct tcagcatcat atttacaata gattaaatta
    41221 ccattaggaa cagcatctaa tgctatagac ttagctttat ccaatgatat attttgtgta
    41281 cctaaattat tatcatttaa gtcatcatct ttttcaattt ctattatttt accagagtag
    41341 gcatcaattt ctatctcata taggatatta tcctttataa ctttgcagtc atattcatta
    41401 tcatcttcat cataataaca aactaaaata ttgcttcctg gaagagcttg ttttaatatt
    41461 tctttagcct gtattaaaga tattttttta gttttatttc ttatgttcac attttttagt
    41521 tttaaaatat cttcaaatgc tttttgatta tatcctcctc ctacttgtgt tatttcatct
    41581 atatctttat ttttaataaa ttctttttga ctatttacaa ggctaccatt agatatcatt
    41641 ataggagaat tttctttagc agctagtact cctattgata atgaatctac taatgcattt
    41701 tcttggttaa taccatcttt agctacaaat acattattta tttttttatc tttataaaat
    41761 ttatcaataa tttttgcatt agtattgttt ctatctgaac cactgattct ttctctgttt
    41821 ggatatttct ttactgtatt gtctgataaa atcttatttc ctccaactat gtaagatttt
    41881 tttatagacc tattgtttaa gaaatttata ctactatcat tgctgttttc atctgatact
    41941 aatattatag gcatattatg tattgctgct ggagaagcta tactaactgc atcagatagt
    42001 ccctttagtc catttacaac tgcaacattt tctacctttt ttatcttatc tatttcttta
    42061 agtacatttg tagacatttc atatatattg tttcctacta ttttatttat ttttatgtta
    42121 agtgatttta tttcattttc tactttagaa gaaatgctat ttccactatc tacaatgtac
    42181 acattatcta caccaagcct tttaagctca gccttagttg aattttcaat actgttgttg
    42241 tttactaaaa gtataggtgc attctttagc ttagcaaatg gatttgcaca aagcgcactt
    42301 tgaatagaat taccattaac tataatggct gtttttgatt gaacccatcc caatttactt
    42361 acttctactg ctgtttcata tcttgtttta cctattaatc tttcttgctt tgtagtattg
    42421 tctgcaaaaa ttgctgaaga actagaaaaa aacataatac ctgatattaa tatagctaaa
    42481 tttttcttat tcatattttt acctcacaat ctttaaaaat ttgttattta gcatacttaa
    42541 taaaatataa tcttaaaatc aaattgatgc tgagtttgaa gttacaaaat caacaaataa
    42601 gattttttta atacaaaatt ttccttttta tatttaacat tgtatcacaa atataaaaag
    42661 gaaaaaactt tttaaaaagg gtatacacta ttcatttttt atcttataaa taagtcttta
    42721 ccactgtttt atatatttta aaatagacac aagacctatt tctaaatctt ttaggtgaaa
    42781 tttcttttta aacatatcta aaaagtattt gtagtaatat taatggactg aatttcttaa
    42841 agtatatatt tctttacatg ttggagtttg tgaagtttga gaattggagg gtgaaagaaa
    42901 catgtaatgg attaatatta aagaactgta tttttataat atttgtctta aaaataaaaa
    42961 aatctattga cttgaagtta actccaagta gtaaagtata attatacaag aattatatac
    43021 ttgtaagaat agttaaagta gagagaaaaa acaaacaagt tttaaagggg gaagtaaaac
    43081 aatggaggca aaaaaattag gatttggatt aatgcgttta ccaataaaag atgaaaatga
    43141 tgttacaact attgatatgg aacatttaaa taaaatggta gacacttttt tagaaagggg
    43201 atttacatat tttgatacag cctatgtgta tcacatggga aaaagtgaga tagcacttag
    43261 agaatctcta gtaaaaagac acaaaagaga gagttttact atagctacaa aacttccatt
    43321 aatggcttta aagaaaaaag aagagcaaga aaccattttt aatgagcaat tagaaaaatg
    43381 tggtgtagac tattttgact actatctttt acacaatata ggcgtgtcac attatgaagt
    43441 agctaaaaaa tttgatagct ttaagtttat tgaagaaaag aaaaaagaag gaaaaataaa
    43501 gaatattggt ttttcttttc atgatagtgc agaattattg gataaagtct tgagtgagca
    43561 tccagaagta gacttcgtgc aattacagat taattattta gattgggata atgaaagcat
    43621 acaatctaga aaatgctacg aggtggcaga gaagcataat aagcctgtaa ttgttatgga
    43681 gccagtaaaa ggaggtacac ttgcaaagat accagaaaaa gcagagaaat tattgaatga
    43741 ctacaatcca gatatgtcaa tttcatcttg ggcaatacgt tttgcagcaa gtaaagataa
    43801 tgttatgatg gtcttaagtg ggatgtcaaa tatggaacaa ttattagaca atacaggata
    43861 tatgcaaaat ttcaaaccat tcgtacaaga ggaatataat attatagatg aagcagtaga
    43921 gattatcaac gaatcaattt tagttccttg tactgcctgt cagtattgtg tagaaggctg
    43981 tccaaaaaat atcgctattc caaactattt tgcgttgtac aatgcagaaa aacaagctct
    44041 taatactgga ttttcaacac agatggtcta ctataataat tatactaaaa cttatggaaa
    44101 ggcctcagat tgtattgaat gtaaacaatg tgaagaaagc tgtcctcaac acattaaaat
    44161 tatagatgct ttaaagaatg tagcagaaac ctttgagaaa taattcaatc tatacaatat
    44221 caagaggaga agatatgtat gacgatttca gaagttagta aaaaatacga gctttcagcg
    44281 gatactttac gatattatga acgaattggt ttaataccac ctgtaaatag aaataaaagt
    44341 ggaattaggt cttttacaga agaagattgt gagtgggtta atttcataaa gtgtatgaga
    44401 ggtgcaggtc tttctattga gacattaatt gagtatgtag ctatgtttca acaagggagc
    44461 agtactatca aagctagaaa agaactttta atagagcaga gaaaccaact agcaaaaaga
    44521 atagaagaaa tgcaaaaaac tttggaacga ttaaatttta agattgatag atatgaagaa
    44581 ggtattattg agaaagaaaa agtattaaag agcagtagaa ataagaaaat ggaggcagta
    44641 tcttatgagt aaaaatgtat taatagtatc agctagtcct agaaaaggtg gaaattctga
    44701 tttattgtgt gaccagttta tacaaggggt attagaatct aaaaatcaag tggagaagat
    44761 atttttaaaa gataaagata ttaactattg tactggatgt ggtgcttgtt atgaaaaaga
    44821 agcaaattgt tcacagacag atgacatggg agaaattctt gaaaaaatga ttgaggcaga
    44881 tgtgattgtt ttagcgactc cagtttattt ttatactatg aatgcgcaaa tgaaaactat
    44941 gattgataga acttgctcta gatatactga aatttgtgat aaagatttct attttatcgt
    45001 tacagcagca gatgaaaatg tggctgatat ggaaagaaca atagaaggat ttagaggatt
    45061 tacatcatgt ctaaatggtt ctaaggaaaa aggtatagta tatggtgtag gtgcttggaa
    45121 tgtaggtgat attaagggaa gtaaggcaat gaaacaggca tatgaaatgg gtaagttggc
    45181 gtagtatgtt tgtataaaat tgtataaaat tgaatatatt cttatcattt caacaataaa
    45241 aagaggctta tctgtatttt gagacagcct ctttgtgcta tatcatttat ttttattcta
    45301 tatccttatt atacccttta tttttttatg cctatttaag tatctgttgt tactcatata
    45361 ttttaataat tacccttaaa aaactataca gattcctgca taatattatt ttctttagta
    45421 attaattttt ctaggttttt ccaatccatt tcttccatat ttgcaaaata atgaccactt
    45481 cctatgcaag tcaggtaaga ctttccatct aattcaaacg aagaacctcc aatacacttt
    45541 gaattacatt tcttacaagt acgagtttta gttatactat ctttaatagt tttagagcat
    45601 tcctccacag catctttata tgtatttaga tgaaaaagat ttgctttaac tctccatttt
    45661 ttttcattac attcaatagt aaataagcta cgttttggtt tcttagttga atatactatt
    45721 ttgtaagaac gagcacctgt ttttggttca attttacaat ctaatgattt accaagttca
    45781 tgtaaatgac atgcaatatc ataatcttta ccacttagta cttctaacat ttcttctgtt
    45841 gtttctgctg ttaattcact tttgctcata ttaaaaaaat ccccctatat aaataataat
    45901 ttcatatgaa aataattaat ataagtatat taaataaaac tattaaaatc aataaaatta
    45961 ctgcaatctt acattattgg gcatagaatg agagctaatg atttattaga aataagactt
    46021 aatagtatga aaatttactt agacgtggta caattctata aaagatttaa aactaggaaa
    46081 ggagaaagtt gttgagatac ggccaatata acaatttatt tataagttgt aaatttatta
    46141 tgagattaat tagattgtta agtaatacta tcaaaaggta gttttttgga ttttcagcaa
    46201 cagtggtaga tattgataat tttttggtta ttattatatt tagctgttat attttcaata
    46261 ggctctatga taactagggt aaataaggta tgggtaaagg ttttattatt tataatagtg
    46321 ggattgtcaa ctatagttct ttcatatgta ataacttgat tatgcaaaat tctatgaagc
    46381 aggaaccctg tgactttagt catgggaggt tcagaattta aggttaaaaa ataactttaa
    46441 tctgtaaatt ctcaaaacaa gaattctcat gttggtaaat ttctagatat gagaaaaaaa
    46501 ttgacatcat aaaaaagtaa ttttagagcg tttttttacg aaaaaattca gaagtaacta
    46561 ttttgaatga cttcacaaaa ttttatatat aaataaagtt tggcacgtta attgctttaa
    46621 taaaagttaa caagacacaa ataaacataa tcatctaagt attgattatt tgaagtttta
    46681 gatttgaagt ttaatctaaa ggttcgtatt aatattggtg tttaggaaat tttattttcc
    46741 tgtaaatata acttaataat aggaggtgaa gtcatgtcaa aagtagtaat agctacagag
    46801 aaagctccag gagcaattgg accatattct caagcaattc aagttggaaa catagtttct
    46861 acatcaggtc aacttccaat agatatgaag actggcgagt tagtatctga cccaaaagaa
    46921 gcaacaaaag cttctttaga taatgtaaaa gcaatattag aacaagctgg tacaagtatg
    46981 gataaaatat ttaagactac agtattcgta aaagatttaa aggattttaa tgatattaat
    47041 gaagtatatg ctacatattt taaagaaaat ccaccagcaa ggtcatgtgt acaagttgct
    47101 caattaccaa aagatgcagt tttagaaatt gaagcaatgg cagtattata agtattataa
    47161 caataaaacc aataacaaaa ctaataaaaa ttaaaaacta ataaaaaaag tctacaatta
    47221 aaaaagttta tattaaaaaa gtctatataa aaatctatct aaatatttaa ctattgagct
    47281 tttctcatat aatgtatatt tttatgtcaa aaatatattt gttatatgag gaaagctttt
    47341 ttttattatt gtattgtgat ttattttatt gtctgcatat tataattaag gttactatat
    47401 aaaacaaact ttttataaat taatattgtc tgttttaacg caaatatata aataagtaat
    47461 gttttatata tattttaaag agtgactata tgttaaaata tagctaaact gataatttgg
    47521 taaattaaat tctaatgggg gaaactatgt taagtaaatt aaaagaattt caacaagaaa
    47581 tgataaaata cactgaaaca gtagctagtg tgttagatgt agatattgaa atagttgacg
    47641 atagattaat aagaattagt ggtacaggtc tgtataaatc aaagataaat gaaagcgttg
    47701 ttactgaggg ctttatttat gacaatgtta tacagacagg tcaggaatta gtcgtattgg
    47761 atatatgtga taatcagctt tgtatagaat gttcccatta catgaaatgc ctaaataaag
    47821 taataatagc agttccaata aagtataata atcgaactat aggagtaatt ggtgctatta
    47881 gtacagataa aactaaaaaa gtagaaataa gtgcaaaaat agataattat ttaaaatttg
    47941 tcaatcatat atgcgattta atttctatga aaatagaaga acatgaagcg tcaaaaaata
    48001 gcagtagaaa aatggatatg atgatagaaa tcattgaaaa tgttgaaaaa ggcgttataa
    48061 tactagacat aaatagcaaa atatcttata taaacaatat agctctaaaa aaattagata
    48121 tagataaaaa tataatagaa aatatagtaa atatagtatc tgttgaatct tcctcaaatg
    48181 gacatgaatt actagaaatt gatattgata acaaaattta taatataaat gccaaaataa
    48241 ttccggtata tccatatata aatcaatacg acaaaataat aatatttgac aagacatata
    48301 tcaatcataa aggacatgga aaagtgaata gtggctgggg aaatagtgat atagagtcta
    48361 taattggaaa ttcagaagca atgttaaaag taaaagagag aactaagaaa ttagcaaagt
    48421 caaattcaac tgtacttata actggggaaa gtggtacggg taaagagcta attgctaggg
    48481 ctatacatgc tgaaggtagc agatggaaca agccatttat tgcgataaac tgtgctgcta
    48541 ttccagaaaa tctccttgaa agtgagctat ttggctatat aaaaggtgca tttagtggag
    48601 ctagtagtgg aggtaaagta ggtaaatttg aacttgcaaa tgaaggtgtt atatttcttg
    48661 atgaaatagg agatttgtca atgcctttac aagcaaagtt acttagagtt ttacaagaga
    48721 gaaaatttgc gagaattggg tcaaataaac ttatagattt agatataaga gtgattgctg
    48781 ctacaaataa aaacttattg aaattagtaa atgaaggtaa gtttagggat gatttatact
    48841 atagattgaa tgtaattcct ataaatttgc cacctcttag ggaaagaaag gatgatattg
    48901 aggcaataat gatgaagttt gcttctaaat attctttaga attaggtatt cagttaaata
    48961 aaatagaaga aaatgtaatg aatatgttga ttaactataa ttggccggga aatataaggg
    49021 aactggaaaa tgcagttgaa tatatgatga atttggttgg agatgatgga ataatatata
    49081 aagatatgct tccattagat attttaaact attataatat taatggaaat atttataaaa
    49141 ataaggatgt aaatataata tttgaagatg atatagttgg agggatagta gagaatcaag
    49201 aaaggatact ttcaattaaa gaattagagt tgacttacat aaacaagttg ttgaataagt
    49261 atggaagaga tacaaagacg aagaagaaga tagcaaaaga cttaggcata ggtttggcta
    49321 cactatatag aaaattggaa gaggaacagt agtaatataa tattaaaatg ataggtattt
    49381 gtgtgttttt atagataggt atttttactt tatggtggag gtgttattat gcaatatgcg
    49441 atagagctgt attatgataa aaaaacggaa aagcaacttt ttgatttatc taaaaaaatc
    49501 gctgatgaaa aaattagtac gaagtattta gaatggaaaa caagacctca tcttactttg
    49561 gcttgtttca atgatgtgga tgaggcttgt tgtatagaca agctaaaggg gtttgcacaa
    49621 aaccataagg taatacctgc ttacattggt tcagtaggca tgtttaatga tactaaaacg
    49681 gtgtttgtat cacctataat gaatagcagt atgtagcagt ttcagagaga attatatgag
    49741 gtactacaag attttgattc aaatggttgg gaatggtacc accccaatcg ttgggtaccc
    49801 cattgcacaa tagcacttac tggagatgat gaaagtgagg ctttttttcg ggcaagtgat
    49861 gtattactgc gtgagttcaa aaaaataagt ggtgagtttg tctcaatagg attggttaaa
    49921 attacatttc ctgtggaaga aatttttaca gtgaatatga ataggtaact ttaactctgt
    49981 tgtggatgtt atgaatattt tgtatagtgc atttcatcag ataaatgcga agttgcgaat
    50041 ttcgacagct caatagtcgc aagtagggca caatggtaca catattgcac ttttgcttat
    50101 tggggggacg cccatgtaaa cttctgtaag aagctatgaa aagatttaag ccattttgga
    50161 ggctttgggt aataaagaat atttgggtaa taaagaatat aaagtatata aatttataga
    50221 gtttatgcgt aagaaggtta tagccatata tttatagaaa ataaaagtag taatatatct
    50281 gacaaaacaa tagacatata aaaaataaga gcataataaa ggaagaatta agataaataa
    50341 acgatttctc gaattgataa ttctcgtatt gataaaaatt tcccaatatg agaatttttt
    50401 cttttataaa tcttattttt cacactcaaa
//
LOCUS       DAYAOO010000022        49807 bp    DNA     linear   BCT 12-OCT-2024
DEFINITION  TPA_asm: Clostridioides difficile isolate ST8-SSI-h139-18
            SAMN40601845-rid21577343.denovo.022, whole genome shotgun sequence.
ACCESSION   DAYAOO010000022 DAYAOO010000000
VERSION     DAYAOO010000022.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN40601845
            Sequence Read Archive: SRR28438827
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 49807)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 49807)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-MAY-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-MAY-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002157583.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002157583.1
            Genome Coverage       :: 163x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/11/2024 16:19:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 4,038
            CDSs (total)                      :: 3,963
            Genes (coding)                    :: 3,930
            CDSs (with protein)               :: 3,930
            Genes (RNA)                       :: 75
            rRNAs                             :: 6, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 60
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 33
            CDSs (without protein)            :: 33
            Pseudo Genes (ambiguous residues) :: 0 of 33
            Pseudo Genes (frameshifted)       :: 7 of 33
            Pseudo Genes (incomplete)         :: 25 of 33
            Pseudo Genes (internal stop)      :: 11 of 33
            Pseudo Genes (multiple problems)  :: 8 of 33
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..49807
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN40601845-rid21577343.denovo.022"
                     /isolate="ST8-SSI-h139-18"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Denmark"
                     /collection_date="2018"
                     /collected_by="Statens Serum Institute"
     gene            complement(186..995)
                     /locus_tag="ACGI5H_001394"
     CDS             complement(186..995)
                     /locus_tag="ACGI5H_001394"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422725.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HFG9697105.1"
                     /translation="MYYVYVNDINIAVYDLNPSAKKTVLFIHGWPLGHKIFEYQTNIL
                     PKLGYRTVSIDLRGFGKSDATSGGYTYSQLADDIYKVVHAIGLKDFTLVGFSMGGAIV
                     LRYMSLFNGYGVSKLVLAAAAAPSFVQRPPEFPYGMTREDVNKLIAQACTDRPEMVTD
                     FGEKVFASNPPESFRRWFNDIGFSASGIGTIGTAVSLRDEELFNDLKCVRVPTGIFHG
                     KLDEICPYEFAVFMNEKIEDSILYTFEYSGHAIFYDELKLFNQEFLQFLEE"
     gene            complement(1079..1612)
                     /locus_tag="ACGI5H_001395"
     CDS             complement(1079..1612)
                     /locus_tag="ACGI5H_001395"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891170.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="manganese catalase family protein"
                     /protein_id="HFG9697106.1"
                     /translation="MSGAHYDMHKRNGYSSDEPYPEIKVLGPNKYYAELLMDDYAGVS
                     SEFTSVNQYLYHNFDLDETHRELSEMWINISITEMLHMEILAKTIRLLGGNPVYRGST
                     SSCGAYWNGGFVCYGNSICNRLKLDLHLEHVAINNYYKDISLIEDPYIKAILNRIILD
                     EKLHVSLFEKAIEKYCK"
     gene            complement(1762..3111)
                     /locus_tag="ACGI5H_001396"
     CDS             complement(1762..3111)
                     /locus_tag="ACGI5H_001396"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728957.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metallopeptidase TldD-related protein"
                     /protein_id="HFG9697107.1"
                     /translation="MELKNFKDILFKKALSEGFEECEIYYYTGENLSINIYEGEVEKY
                     NLDKSFGLSFRGKVNGKIGYSYTEILDDKAVDMLIKNVKDGVNTIENEDVQFIYEGDK
                     HYNDVKTYSKELENLEADKLIDLALEMERETKAYSDKVVNLSKCTISYSVSSNGISNT
                     KGLNLSNKTNMLIGFVVPIIEDNGQKYDGIGYNIANSIEEIKPCEIAKLGVDNALSKV
                     GGKSITSGKYKTILLNEAMVSLLSTFSGIFNADSAQKGLSLLKNREGDMIASPIVTIV
                     DDPLLENGMASTPFDDEGVATFKKEVVLNGKLITLLHNLKTANKAGVKTTGNGIKSSY
                     SSPISIYPTNFYIEKGDKSLDEIIKDIDEGLMVTSFAGLHSGANSVTGDFSLAAKGFY
                     IKEGKKVFPVEQITVAGNYFDLLKDIEAIGEDLEFPMSSIGSPSVVIKELSVAGKDE"
     gene            complement(3123..4505)
                     /locus_tag="ACGI5H_001397"
     CDS             complement(3123..4505)
                     /locus_tag="ACGI5H_001397"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898042.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TldD/PmbA family protein"
                     /protein_id="HFG9697108.1"
                     /translation="MLSKNIASKVLEKCLITGGDFAEIFEEDTINNSISLIDNKVENA
                     IGGRNYGIGIRIFKGLKSIYAYTSDNSLNSLLDVAYKAAVALGKLEDGKSVILNDSIK
                     INNIHNIKIYPNSIGNKDKVSVMKVAYKSAKEFSNDISQVSVSYLDKDQKILIANTEG
                     IYVEDRRIRTRLGISSIASKGNENQTGFEGPGGCKGFEIFEEIDPEYYAKESARVAHT
                     MLHAKNCPAGNMMVAIDNGFGGVIFHEACGHSLEATSVAKGNSVFADKLGQQIASTKI
                     TAIDDGTIPNYWGSMNIDDEGNPTQKNILIESGILKSYMIDKLNGRRMGMNPTGSSRR
                     QNYKFAPTSRMTNTYIAAGEDRPEDIIKSIPDGLYAKKMGGGSVNPVTGEFNFAVSEG
                     YLIKNGEIQEPVRGASLIGKGSDILMNIDMVGNNVKQAQGMCGSSSGSIPTNVGQPMI
                     RVKEITVGGR"
     gene            4749..5963
                     /locus_tag="ACGI5H_001398"
     CDS             4749..5963
                     /locus_tag="ACGI5H_001398"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861720.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-dependent oxidoreductase"
                     /protein_id="HFG9697109.1"
                     /translation="MNQEYVKGNPIFTNINKVPRQFPYLTDDIDTDVIIVGGGVTGCI
                     CAYYLAKNNIKSVILEKGRIAHGSTSVTTSLLQYELDDNLIDLTEVMTLKDALKAYNL
                     CTSALEELDTFIELYGNKCDYAKRDTLLYTANKLEVKAIKEEYNLRKENGFDVEYIDE
                     STNPFSFDLKSGLIAKNGGRELDPYKYSHHLIDVSLKNGLQVYENTEVKKVDLSNDKV
                     TAEVSYGYKVHGKKLIVATGYNTSLFTKRNFATKSNTFNIATKPLKNIASWKNNILIR
                     DNCDPYNYLRTTKDNRLIIGGEDVSFDDIENETLANEKYDILEQRLKSMFKDIKDIEV
                     EYKYCGCFASTLDNLGFIGPDNKNNNLWYCLGYGANGILFAILGGIMLSELYLGKQNK
                     NMKLFKVDRFDK"
     gene            6140..8053
                     /locus_tag="ACGI5H_001399"
     CDS             6140..8053
                     /locus_tag="ACGI5H_001399"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439629.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0008134 - transcription factor binding
                     [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sigma 54-interacting transcriptional regulator"
                     /protein_id="HFG9697110.1"
                     /translation="MKYGGIIMKEILVIAPTKGTYEKSIHIVKKNKYTNIDVVFGNLK
                     EGIPLAEKSINHGTRIIISRGGTYNMLKATYNIPIVEIKVDAYDIIKSYKEVKNSNEP
                     FGIIGFNNVIYGFDIIEEILNKKITMIEIEKEEEIYDAIEKYRKKGINTYIGDTTVAH
                     IVKRLNCKGILIESREENILRAIQQAEQILEATKDEQKRRLQIEAMTDFVHDGIITVD
                     KNFKITLFNKSAEKIFGIKKENALYHNVVDVIPNTVLPQVVETMEPQIGEIQNIGSTK
                     IITNRVPIIVDGQIQGAVSTFQDSKEISSFEHTIRRSLLSKGLSAKYTFDDIIHASEK
                     TKDCIELAKKYACYDTPMIITGESGVGKELFCQSIHNYSKRKNAPFVAVNCAAIPPSL
                     IESEFFGYEEGSFTGARKKGKAGVFELAHEGTIFLDEISEIPLELQGRLLRVLQEKQV
                     MRIGGDKVIPIDVKIICASNKDLKNMMRNGLFRQDLYFRINILTLYLPSLKERKEDII
                     KLSEFFIHKYSSKYNKTPLIITPNIKKALLEREYEGNIRELEGMMERAVIVESFDSIL
                     LEKLSNEYTNNIVDKDNSDFECSNLDLKTLEKKYIYKIYNENNRNTTKTCEILKITRS
                     TLWRKLKEIEDDV"
     gene            8324..9298
                     /locus_tag="ACGI5H_001400"
     CDS             8324..9298
                     /locus_tag="ACGI5H_001400"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426739.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-keto-3-deoxygluconate permease"
                     /protein_id="HFG9697111.1"
                     /translation="MHILKSVKKIPGGLMVCPLLLGALFNTVCPQALEIGGFTTSLFK
                     TGAMSILALFCLCNGAQINIRQAGKPLTKGIVLTATKFIIGAVLGIIVSKFIGPKGII
                     GITPLAIVATMTNSNGGLFAALAGEYGDSTDVGAISILSLNDGPFFTMLAFGVTGLAN
                     VPIVALFAALIPILLGFILGNLDEDIREFLAPGTTLLIPFFAFPLGAALNFNQIITAG
                     LPGVVLGLGVTIITGMGGYFVMKLIRAEHPAVGAATGTTAGNAAGTPEALAAIDPTLA
                     TIAAVSTVQVAAAIIVTAICCPMLVSYLDKREKKKKSIFKTNKNIEVN"
     gene            9319..9594
                     /locus_tag="ACGI5H_001401"
     CDS             9319..9594
                     /locus_tag="ACGI5H_001401"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426740.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UxaA family hydrolase"
                     /protein_id="HFG9697112.1"
                     /translation="MNAIIHANEKDNLVTCVRPLIKGEKVSIDGKSYIVNDNIPVFHK
                     MATEDVKKGDVVYKYGEIIGIATVDIKTGDYVHVHNIESTRGRGDKK"
     gene            9607..10770
                     /locus_tag="ACGI5H_001402"
     CDS             9607..10770
                     /locus_tag="ACGI5H_001402"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898047.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UxaA family hydrolase"
                     /protein_id="HFG9697113.1"
                     /translation="MKLMGYLRENGQFGIRNHVLIIPTSVCSSETATRIASLVPGAIA
                     IPHQHGCCQIGSDIELTAKTLIGFGKNPNVAAVLVVGLGCDGIQAKELASEIATTGKK
                     VNYVVIQECGGTLKTVSKGAEIVSKMAREVSKEVRVEFGMSEITLALECGGSDPTSGI
                     ASNPSIGVASNLLVDEGGSSILSETTEVIGAEHLLATRFEDEEMKDKFLKFVSDVEKR
                     AIAMGEDLRSGQPTPGNKAGGLSTIEEKSLGCMYKAGNKPFKGALEYADIVPPDKKGL
                     YFMDTPGQDIDSITGMVAGGAQIVIFSTGRGTPTGSPISPVIKITGNSDTYNKMPDNI
                     DINAGRIITDGAKIADIGQEIFNEIIEVCNGKHTKAESLGHREFGIYRISSTF"
     gene            11107..13386
                     /locus_tag="ACGI5H_001403"
     CDS             11107..13386
                     /locus_tag="ACGI5H_001403"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439637.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EAL domain-containing protein"
                     /protein_id="HFG9697114.1"
                     /translation="MNFENTKNKKIIATLLLTLLLIVSLTCVTFIMNLNKVTHNETER
                     YLVEVSQSISTTINVKCKSIFRTLYSMGDTYFEINDSEKEVNRYLSKKLKLFEFDWLG
                     IIDSNGNFVSALKDTGNVKGQDFYRKALQGKETITPVKSQSGTYGILYSVPLYNGDKI
                     VGAVAAWNTIDTMRNLLSVESFHGEGFSQIIDQDGNFIVSSANKNAPKNVVNFFDMIK
                     HQGKQVDKNKLEEMKINLKKNKTGSMYYTLNDGISKAMHYLPLQEENLYLLSIVPTKT
                     ASAQFDLLLKKAIFINILIVILFLLLIILIMFINQKNRAQLIKIAYVDSVTKGYSKAR
                     FDIEAKKIIQSSSSESYSLVSINIQKFKLINDSFGSEAGDKTLKYIHDVISNYLEPGE
                     LLCRVSNDQFNVLIKTIPQKEILKYIENITNDINSFNKNEECKYFIALSIGVYKIDDP
                     NLPLVSIQDRANVARKNNKGNIGNHPLYTCVFYSDLERLKMIKEKEMENRMEEALNNN
                     EFIVYLQPKISLKDNTIVGAEALVRWQDPNKGLIPPDEFIPFFEKNGFITKLDHYVFE
                     KVCSMIRKWIDNGETPIPVSVNFSRANLNNIDFLEKYRMLRNKYNIPAKLLEIELTET
                     LVFENLQKLINIIDQIHEEGFQCSLDDFGSGYSSLNMLKEIKVDTLKLDRAFFSSPNA
                     DNIAENHVIESIVNLAKKLNMNSISEGVETILQMDYLKKINCDMIQGYVFSKPLPQEI
                     FEKMTFGKKLEETSMDSSV"
     gene            complement(13481..14821)
                     /locus_tag="ACGI5H_001404"
     CDS             complement(13481..14821)
                     /locus_tag="ACGI5H_001404"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439673.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0042910 - xenobiotic transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0006855 - xenobiotic transmembrane
                     transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MATE family efflux transporter"
                     /protein_id="HFG9697115.1"
                     /translation="MENQEALRHEKIWILLFRYSIPAIIAMMVTSLYNVVDRAFIGSM
                     EGIGSIAIAGLGVTMPVFTLIIAFGMLVSVGASTRLSIKLGERNREEAEKILGNALTL
                     SIIISLIITILGLVFLEDILFILGASKDSIFYAKDYMSVILVGSIFNLVAFSLNNAIR
                     AEGNPKLAARTMIVGCVLNLILDPIFIFVFNLGIKGAAIATVLCQIVVFFWVIHYFIR
                     GKSNLKLKKCNLKLNKDIVKKVFAIGMTPFAMEVAISITHMFTNNSLKVYGGDLAIGA
                     MTALTSILLMFMMPVFGLNQGMQTIISYNYGAKQYERAKKTLILSIIVSVVILSFGFL
                     VVQVFPEVFVGIFNKDSDLMDIAVRGISLNLITLPIMGISIVGPVYFQCISKVKHSMF
                     LTLLRQFILFIPLIIVLPIQFNLDGVWLAQPVADFIAMIIVLLFLKREFKTSRV"
     gene            complement(14833..15615)
                     /locus_tag="ACGI5H_001405"
     CDS             complement(14833..15615)
                     /locus_tag="ACGI5H_001405"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861723.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HFG9697116.1"
                     /translation="MNCINTKNLNVSYGNTDIIKNLNLNIPKGKITTIIGANGCGKST
                     ILKTIGRIISPNSGKIYINGEDIYKKKSKEIAKDMAVLPQSPQAPSGLTVSELISYGR
                     FPHKSGFGNSSKEDREIVNWSLEVTGIAEFKDRNMEDLSGGQRQRAWIAMALAQETDI
                     LLLDEPTTYLDLAHQLEILKLLDELNKKQGRTIVMVIHELNNAARFADHMIGIKKGKI
                     VCEGDAYDVMTKDNLKELFNIDAEIATDPRTNKPICITYDMV"
     gene            complement(15630..16652)
                     /locus_tag="ACGI5H_001406"
     CDS             complement(15630..16652)
                     /locus_tag="ACGI5H_001406"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439679.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="FecCD family ABC transporter permease"
                     /protein_id="HFG9697117.1"
                     /translation="MKNIIKINSKTLLVISILMVLIFITFLLSLNMGSFSIEPMDVIK
                     TFLGQGQRNHEIAIFKLRLPRIVIALLVGSALSTAGVILQGVTKNDLADSGILGINSG
                     AALFVVVYIYLMNGNVYEGMSNLTVFTMPIVALIGALFGAFLIYSLAWKGGINSSRLL
                     LIGIGVNIAFTSILTIFQLKFTTQEFNRVMAWTSGSIWGTSWKYVIAVLPFIVIFMGI
                     TIYKSKYIDVLNLGDEVSISLGVDVEKQRRRLIIYAVILSGVSTAVAGSISFLGLIAP
                     HIGRKIIGPKHKRLIPVSALIGTLLLLIADTISRNLLAPIEIPVGIVVSIIGVPYFIY
                     LMLVND"
     gene            complement(16658..17671)
                     /locus_tag="ACGI5H_001407"
     CDS             complement(16658..17671)
                     /locus_tag="ACGI5H_001407"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439682.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="FecCD family ABC transporter permease"
                     /protein_id="HFG9697118.1"
                     /translation="MTKLSKKNITYLLILVSIVVLVFGIVLSITIGAKDMNLSTVIDS
                     LIKMEDGINMRIVKDVRLPRAIAAALVGGFLAVSGAIMQGITRNPIAEPSVIGITQGA
                     TFAISISLVLQKKLPQLIHGSFSVMMFAFIGASISGLFIYFISSKSRGRVNNVKLALA
                     GVALGTLLISLASAISMYFNLSQQLSFWISGGLVGVKWEGIKLLFVAGGIGFILAIIM
                     APRITILSLGEEVAIGLGQKTNFVRFICIVLVILMTGASVSVSGNIIFIGLIVPQIAK
                     GIVGSDYKYIIPSSLVLGAVLLVYTDILSRMINPPYETPVGSITALIGVPIFIYLVRK
                     GEK"
     gene            complement(17799..18737)
                     /locus_tag="ACGI5H_001408"
     CDS             complement(17799..18737)
                     /locus_tag="ACGI5H_001408"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898056.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HFG9697119.1"
                     /translation="MKKIKSLAIFISIITTLVLVTACSDKNTEDKDKSETRVVQSVKG
                     EVKIPSNPKKIVDISGSSEELLLAGYKPVATANVDSYETDKLPSYIREELKGVKIVGH
                     SMMDTMDMEAILEVNPDLIIMSQRQEKIYDQLKEIAPVVMMKDYANDWRSKLTDVSKL
                     FDKEEEAKSWLQKYDEKATKLGKEVIEKNGEKTYLPVLASSGQFMVFSDGGIGTLIND
                     DMKLAKPKNMPKQDGITLPMVSMEGLTDIDADHIVVIATEADKKDLENSAIWAQIRAV
                     KDGNVTILDAAPFFSQSYNPIGKELLLESVKNELTK"
     gene            19007..19471
                     /locus_tag="ACGI5H_001409"
     CDS             19007..19471
                     /locus_tag="ACGI5H_001409"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016208838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9697120.1"
                     /translation="MVHLVYCDNAGKKGEKVLDKILAGTKTMVIRGAAGRKIPHSRVF
                     EDELLYFMEKGTAKISAKATVKKVENYVKLTEDEISKILNENQPKLNLSEKQKVRWHK
                     KCLCLVEFENVEEITPLDFDHQGNMDDWLIVEKIEDVVVGTSIPYNYEKSKF"
     gene            complement(19583..19900)
                     /locus_tag="ACGI5H_001410"
     CDS             complement(19583..19900)
                     /locus_tag="ACGI5H_001410"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435715.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose/cellobiose transporter subunit IIA"
                     /protein_id="HFG9697121.1"
                     /translation="MDEKMIEISFGIIGFAGDAKGLAFEAIKEAKSGNIDKARECIEK
                     SKESIHKAHKFQTELIQNEANGNKTEISVILIHAQDHLMTAMNFQQLAEEFIDVYERL
                     ESK"
     gene            complement(19913..20644)
                     /gene="chbG"
                     /locus_tag="ACGI5H_001411"
     CDS             complement(19913..20644)
                     /gene="chbG"
                     /locus_tag="ACGI5H_001411"
                     /EC_number="3.5.1.105"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439691.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016811 - hydrolase activity, acting on
                     carbon-nitrogen (but not peptide) bonds, in linear amides
                     [Evidence IEA];
                     GO_process: GO:0000272 - polysaccharide catabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="chitin disaccharide deacetylase"
                     /protein_id="HFG9697122.1"
                     /translation="MTKIIINADDFGYCEAVNYGIISAHNNGIVRSTSMMANMPGVEH
                     GVGLLKENKTLNCGVHMTLSCGRPLLSNLKTIVDKDGFFIRRITDEIIEKMDCDEIYR
                     ELCAQIDRVKGLGIDISHLDSHHHIHTLLSLKPVIEKIVTKYNLPIRGGFEYNLEYSK
                     VVPLIDSFYKENVSEEYFIKNIDEIMKYDVVDIMSHPAFLDDYILNSTSYAIDRTKEH
                     KILTSKKVKEFLEKNGLVISSYRDI"
     gene            complement(20670..21980)
                     /locus_tag="ACGI5H_001412"
     CDS             complement(20670..21980)
                     /locus_tag="ACGI5H_001412"
                     /EC_number="3.2.1.86"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861728.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008706 - 6-phospho-beta-glucosidase
                     activity [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="6-phospho-beta-glucosidase"
                     /protein_id="HFG9697123.1"
                     /translation="MKKGLKIVTIGGGSSYTPELVEGFINRYEELPVKELWLVDIEAG
                     KEKLEIVGNLAKRMVKKAGVDMKINLTLDRREALRDADFVTTQLRVGLLDARIKDETI
                     PLSHGVMGQETNGAGGLFKALRTIPVIFDIIKDVEELCPNAWMVNFTNPTGIITEAVF
                     KYTNFRRYIGLCNVPIHLKNDVAKLFNVESDRISMDFAGLNHMVYGLNVSLDGEDVTK
                     EAIDKFVKADISMQNIKAIDFNAEFVKSLGAIPCPYHRYYYKTKEMLEDELREFKEGK
                     ARGQVVKELEEQLFELYKDEKLDVKPPQLEKRGGAYYSDAACNLISSIYNDKKDIQVV
                     NTLNKGSIRDFKDEQAVEVSSVITKNGPKPISIGYLPDSVHGLVSQIKSFEVLAAKAA
                     VYGDYESALLALCINPLIPSDDLAKTILDEMLEAHKDYLPRFNR"
     gene            complement(22077..23390)
                     /locus_tag="ACGI5H_001413"
     CDS             complement(22077..23390)
                     /locus_tag="ACGI5H_001413"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422690.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HFG9697124.1"
                     /translation="MEKFMSFMDKYIVPVAAKIGAQRHLVAVRDAFIVMIPITMVGAL
                     GTLINNLPLEAYKNLMASIFGENWTTFGGDLWWGAIGTMAVFLVIGVAYFLAKSYESD
                     GLQSGLIALSIFFIMAPQIGKIVPEGGTTVVEGWGMIQQTYLGTAALFSSILIGLLST
                     EIFVRLSKVKKLTIKMPDGVPPAVSRSFAKLIPGMLTIMIFTVIGIFIKMLSNGSFLT
                     DILNTYLGAPLSNVADSLGSTMLIAFIIHILWTVGLHGANIALPFTETILMKLGGENA
                     ALAQAGATEGYHVLAGAFFDAFVYLGGSGMVLGLIVALLIAGRRRKEMIVLGGPPAIF
                     NIGEPLIFGLPIVLNPIFMIPFVLAPVICSAVSYLAIDFGLVAPVILPKIPWVTPPIL
                     GGAMATGDWTGGALALFNLILSILIYIPFVIASEKMEANKLKINN"
     gene            complement(23412..23723)
                     /locus_tag="ACGI5H_001414"
     CDS             complement(23412..23723)
                     /locus_tag="ACGI5H_001414"
                     /EC_number="2.7.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422688.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HFG9697125.1"
                     /translation="MIKIMLACSAGMSTSLLVTKMEDAAKENGIEAKIWAISEVNLKN
                     EIENCDVLLLGPQVRYVLGKATEMAKPYNIPVEVINMMDYGRCNGKAVLDRAVELNSS
                     K"
     gene            complement(23923..24627)
                     /locus_tag="ACGI5H_001415"
     CDS             complement(23923..24627)
                     /locus_tag="ACGI5H_001415"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426754.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HFG9697126.1"
                     /translation="MKEPIYKVIENHVRELINSDSLKEGDLIPSEKQLSEEFNVTRMT
                     VRSALNNLVKEGYITRQRGVGSIVIANNIYDNISSVSGFTKEMESKGYKVSNILVSLE
                     IVQADENLSSKLNISLEENVWEIKRVRLANDVRVSYMITYMPVKLFPNLNKTHCENSL
                     YNFVEEVCGYKIAMSEREVQAVISNEECMDNLKLEEPEPLLYISQICKLQNSEIFEYS
                     HTYHYGYTLTLNAVVE"
     gene            complement(24718..26079)
                     /locus_tag="ACGI5H_001416"
     CDS             complement(24718..26079)
                     /locus_tag="ACGI5H_001416"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861729.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MATE family efflux transporter"
                     /protein_id="HFG9697127.1"
                     /translation="MKDRLNLTEGRITEKLLKLSLPIMGTSFIQMGYNMIDMIWVGKA
                     GSKAVAAVGTAGFFPWLAMAFIMISKVGGEIKVAQSIGANNISTTKSYMKSAIEINII
                     LAIIYTISLIVLNKQLIGFFRLGDLEVITMSRQYLIIVALGMVFYFINPVFTAIFNGL
                     GNSKTPFRINTVGLITNIILDPILIFGWGFAPKLGVAGAAIATVFAQIVVTTCFIYII
                     VKSKEEYFKLRLFKEIETKYYKVLYKLGLPIAIQSGMFTVFSMLLGVIVASWGPVAVA
                     VQKVGSQIEAISWMTAEGLSVALGSFVGQNYGAKKYSRINKGCKIAITVSSVLGIITT
                     LVLVFAGESIFSIFIDESEAIEKGAVYLKILGYSQFFMCLEIITTGAFKGLGRTYIPS
                     IIITILTGARVPLAYFISRPEMLGLNGVWWSITLSSILKGILMISLFISLLKLGKLYK
                     ISE"
     gene            26578..27732
                     /locus_tag="ACGI5H_001417"
     CDS             26578..27732
                     /locus_tag="ACGI5H_001417"
                     /EC_number="2.7.7.65"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426756.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GGDEF domain-containing protein"
                     /protein_id="HFG9697128.1"
                     /translation="MKINKKFNRVDMQVSILTAIIVIISSSCVYFFNYTLTYKSMIYS
                     LSERSKHIYEYVERNIDKNTFTEINSKEDQSKKSYKSSKILLESVKNTTGVMYLYTAK
                     KTKDGSLVYVVDGLNSSRSDFRNAGDLIEKEIWGDLNKALDNHILLPKKIKSTSWGYI
                     FISYFPIHNDVGKVVGVIGIEFEAKHQYNTFKFISIVTPIIALLTCLISALIAVILFK
                     RISNPTYTDFANTDYLTGLKNRNAFEIDMNNLNNSNLKNLISIISIDLDGLKKINDKF
                     GHQTGDLYIKQASKIIQYVINKKYIVYRIGGDEYIIILKNLSHKEINNIINNINLKIV
                     EENSTNELKLSMSIGYAIFDEKVDVSLFDTYRRADSQMYDNKRKINKQYQ"
     gene            complement(27814..29532)
                     /locus_tag="ACGI5H_001418"
     CDS             complement(27814..29532)
                     /locus_tag="ACGI5H_001418"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861730.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0033225 - ATPase-coupled
                     2-aminoethylphosphonate transporter activity [Evidence
                     IEA];
                     GO_process: GO:0033223 - 2-aminoethylphosphonate transport
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="putative 2-aminoethylphosphonate ABC transporter
                     permease subunit"
                     /protein_id="HFG9697129.1"
                     /translation="MNNNAISSKSISLKSKMNLDIKKCMLTVLVMSLVIFLLAPIIYL
                     FVQAFLDKDGVFVGLQNFQEYLASESLLNSLKNTVFVSVISTVISLTLALVYAYALTR
                     TKIKFKGFFKSLAMFPMFAPTMMHAIGLVYLFGNQGLVTNLLGVHVPIYGAVGIILAQ
                     IIYVFPQSFQILYISLSSTDYRLYEASNTMGISKIREFISITIPSIKYSLISSAFVSF
                     TLCFTDFGAPKVIGGEFNVLSIDVYKQIIGQQNMPMGATVSILLLIPAIISFIVTKKI
                     EKNQNSYITSKSIPYKVKTNKLRDSILGGVVGIIAFGIIAVMLTVILSSLISVWPYDL
                     RLTLEHFSMKNSIDGIKPFINSIKMSLLTAILGTSFVFLFAYLNEKTEKAPYLKSFGY
                     FLSTLPMALPGLVLGIAYVLFFNKLEFNFMDTIYIKNLFNGLYGTLLIMVICNIVHFF
                     SVAFITATTAIKKVDKELDMVAKSMGINSASILKNVTIPLCLPAVLENFMYFFLNSMV
                     TISALVFIYTASSKVAAISIVQLDDKGSTAQAASLAVLILVTNILVKVIYEFIKNRLE
                     KRTNFN"
     gene            complement(29537..30526)
                     /locus_tag="ACGI5H_001419"
     CDS             complement(29537..30526)
                     /locus_tag="ACGI5H_001419"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728969.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HFG9697130.1"
                     /translation="MSYLKINNVFKSYDQKRVLNNISLDIEEGEFLCLLGPSGCGKTT
                     LLRIIAGLEDVNSGTIILQDKDITNLEPSKRGFGIVFQSYALFPNMTAYNNIAFPLKE
                     RKVSKGKIDNKVKEVLETVGLTNEAHKYPKALSGGQQQRIAIARALALEPKFLLLDEP
                     MSALDAKVRHKLRMDIKRLQKELNITTIMVTHDQEEAITMADKIAILNGGDIMQIGTP
                     EEIYQNPQNLFTAQFIGDTNCFDNGDSILTVRPEYVQIEKSTKENYQGIISNIEFRGN
                     LLRVEIKDKLNENFIISDASIKEWVNLNLVEGDLVKISIDEKYYLKYPKVKGA"
     gene            complement(30622..31671)
                     /locus_tag="ACGI5H_001420"
     CDS             complement(30622..31671)
                     /locus_tag="ACGI5H_001420"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861761.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009897 - external side of plasma
                     membrane [Evidence IEA];
                     GO_component: GO:0030288 - outer membrane-bounded
                     periplasmic space [Evidence IEA];
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0033225 - ATPase-coupled
                     2-aminoethylphosphonate transporter activity [Evidence
                     IEA];
                     GO_function: GO:0033226 - 2-aminoethylphosphonate binding
                     [Evidence IEA];
                     GO_process: GO:0033223 - 2-aminoethylphosphonate transport
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="putative 2-aminoethylphosphonate ABC transporter
                     substrate-binding protein"
                     /protein_id="HFG9697131.1"
                     /translation="MKEFIFTCLCIVVITFMTSCISTTPQTTQGKGNNKLTIYAALEE
                     EQIAYYMEGFREEYPNIDVEIVMDSHGVIASKLLAEKDNPQADIIWGLSAMNMIELKK
                     DGALEAYKPKNYDKVDKKFKDTEDDVSWVGMSVPETAIVVNYKELKKLGIDIPKSYED
                     LIKPEYKGLITMPNPASSGTGYLTVSGLIQMMGEKDAYNYMDKLHKNIATYTHSGSKP
                     AKLAGSGEYPIGITLGYRATQQLSSGEPIEVVFPKEGSGWDLEANALVKKDNIKKEAK
                     LFLDWAISDSAMDRYAHEVAVTSIKTDNPVPKGYSKQPFEQLIKEVDLNSAAKNRSTV
                     LKTWESKYGSKSESK"
     gene            complement(31948..32616)
                     /locus_tag="ACGI5H_001421"
     CDS             complement(31948..32616)
                     /locus_tag="ACGI5H_001421"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891221.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit D"
                     /protein_id="HFG9697132.1"
                     /translation="MARLNINPTRMEMTRLKKLLKTATRGHKLLKDKLDELMKQFLEI
                     VRENKRLREEAENALDTAYKNFIIARAVMSQEYLGSALMMPKQSVSVDVSTRNIMSVD
                     VPVFDFKTENNQSDIYPYGLAFTSGELDSAMEAFSDAMQPLLRLAESEKSAQLLAQEI
                     EKTRRRVNALENVMIPNYIETIKYIAMKLEENERASTTRLMKVKDMVLKKALEEKKKN
                     DLVV"
     gene            complement(32622..33995)
                     /locus_tag="ACGI5H_001422"
     CDS             complement(32622..33995)
                     /locus_tag="ACGI5H_001422"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422669.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit B"
                     /protein_id="HFG9697133.1"
                     /translation="MIKEYKSIQEVAGPLMLINGVEGVKFDELGEIELSNGEIRRCKV
                     LEVNGDTALVQLFESSTGINLAESKVRFLGKSLDFGVSPDILGRVFSGMGRPIDGGPE
                     IIPDKRLDINGAPINPAARDYPAEFIQTGVSAIDGLNTLVRGQKLPIFSGSGLPHANL
                     AVQIARQAKVRGTDSKFAVVFAAVGITFEDAEFFISDFKATGAIDRSVVFVNLANDPA
                     VERVSTPRMALTAAEYLAFEQDMHVLVIITDITNYAEALREVSAAKKEVPGRRGYPGY
                     LYTDLATMYERAGKMKGHEGSITMIPILTMPEDDKTHPIPDLTGYITEGQIILSRELY
                     KKDIQPPIDVLPSLSRLKDKGIGKGKTREDHADTMNQLFAAYSRGKDAKELMAILGES
                     ALSEIDLMYAKFADEFEKEYVSQGFRTDRTIEQTLEIGWKLLSMLPKSELKRIRDEYF
                     EKYMPKE"
     gene            complement(33992..35770)
                     /locus_tag="ACGI5H_001423"
     CDS             complement(33992..35770)
                     /locus_tag="ACGI5H_001423"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426762.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit A"
                     /protein_id="HFG9697134.1"
                     /translation="MKTGTIVKVSGPLVVAEGMRDANMFDVVRVSDKHLIGEIIEMHG
                     DKASIQVYEETSGLGPGEEVVSLGMPMSVELGPGLISTIYDGIQRPLEKMYDISGTNI
                     TKGVEVSSLDRTTKWEFKPKKSVGDKVVAGDIIGGVQETAVVECKIMVPYGVKGTIKE
                     IYSGEFTVEDTVCVITDEKGNDIPVTMMQKWPVRKERPYREKKTPDSLLVTGQRVIDT
                     FFPITKGGVAAIPGPFGSGKTVTQHQLAKWADADIVVYIGCGERGNEMTDVLLEFPEL
                     KDPRTGESLMQRTVLIANTSDMPVAAREASIYTGITIAEYFRDMGYSVALMADSTSRW
                     AEALREMSGRLEEMPGEEGYPAYLGSRLAQFYERAGKVNCLGMDEREGTLTAIGAVSP
                     PGGDTSEPVSQATLRIVKVFWGLDASLAYKRHFPAINWLTSYSLYQEKVDVWADKNVN
                     DNFSAQRAQAMKLLQVESELQEIVQLVGVDSLSDGDRLILEVTRSIREDFLHQNSFHE
                     VDTYTSLHKQYRMMGLILKFYKSAQDAIKQNVTINDIIKLSVLEKIGRAKYVEEGDID
                     AAYDSIEDEIDNELADLIKKRGAEEL"
     gene            complement(35887..36204)
                     /locus_tag="ACGI5H_001424"
     CDS             complement(35887..36204)
                     /locus_tag="ACGI5H_001424"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893746.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit F"
                     /protein_id="HFG9697135.1"
                     /translation="MYKVGVVGDKDSIMGFLALGIDIFPAYDSDEIKKSIHKLVEDEY
                     AIIYITEQASLLAKESIAKYKDYQLPAIIVIPGIGGSMGLGMNEVRESSKRAIGADIL
                     FKE"
     gene            complement(36197..37174)
                     /locus_tag="ACGI5H_001425"
     CDS             complement(36197..37174)
                     /locus_tag="ACGI5H_001425"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898066.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit C"
                     /protein_id="HFG9697136.1"
                     /translation="MAEEKTYPYAVARIRVLEKQLLNRQMFIQMAEAKSPEDSLRIIA
                     EAGYADTSNNNIHNFENILTQELSKTYEILKSLAPEEKFVDVFLYKNDYHNLKVLIKE
                     EISGVDGEKYLIDGGTIPLIKLRESLANRSFSDLPKIMSSAILEAFDVYNKTQNGQMV
                     DIVLDKATFTSMKETAKESQNKFVIDYVMKVCDLTNLKSFIRVKNMKKDFDMFMNVFV
                     SGGSLDKEKFLEAFSSDTPASCFKSTSYSDVCKNGMDSGFTVFEKLCDDYLMEYVRGA
                     KFKPLTLEPLIAYLYAKESEIKTIRIILTSKLNNIDADTIKERLRDAYV"
     gene            complement(37189..37752)
                     /locus_tag="ACGI5H_001426"
     CDS             complement(37189..37752)
                     /locus_tag="ACGI5H_001426"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422659.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit E"
                     /protein_id="HFG9697137.1"
                     /translation="MGNEQKMIDRIIADAKQEAQEILDKAKSEADLKVNSANEKAEKE
                     MASYTKLAEAEAEKAASKEISGAYMEAKKQILSKKQEILEEVILEAKNKLLNLKDNEY
                     EEIILNMIEKSNCTDDSEIVLSKKDKKTLKDVLSKKGIKVSDETRDITGGFIVKKGDI
                     EYNYSFEAIIAVEHEYIEQIAAEILFN"
     gene            complement(37804..38295)
                     /locus_tag="ACGI5H_001427"
     CDS             complement(37804..38295)
                     /locus_tag="ACGI5H_001427"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422657.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit K"
                     /protein_id="HFG9697138.1"
                     /translation="MEFLNALGNGQFLAISGAAIAALFAGMGSAKGTSIAGQAAAGVV
                     TEDPSKFGQLLVLQLLPGTQGLYGFIIAFLILSKAGIIGGDAIPTSAQGLQLLMAGLP
                     IGLVGLVSGIAQGKAAAAGVGIVAKRPEELGKAITFAAIVETYALLGLLVSFLAYNGI
                     AIG"
     gene            complement(38298..40223)
                     /locus_tag="ACGI5H_001428"
     CDS             complement(38298..40223)
                     /locus_tag="ACGI5H_001428"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit I"
                     /protein_id="HFG9697139.1"
                     /translation="MAIVNMNKISIVGLEAQKSQILKLLMNRGFVQIDDSAFLTEEEE
                     LKNYLVKDSEESEVIMLEQKMSHVNQAINIVSSLVKQKKSLLAPKREFNKIDSEKEGQ
                     VYAEALELNNLHKEIGTIRSNINLLNNNKSMLEPWVNFDIPLENMETKYTKTILGTVP
                     ISANIDALRVKLEDEIPESVIGIVNSDKLMNYVYLITLKETFDDVLEVLKEFNFSVVS
                     LPNEEGTPLQAIKKYNEMIIRQENVSKDKTEEIKRHADSIHMLENLYDFYTIERDQKK
                     IIERLVKTKTTFCLNGWLPSKRADELIKEITEKFNCCVQTEEGSKEEGFPILLENNKL
                     VTPFESVTNMYSYPSTKDIDPNTILTFFFVVFFGMMLSDAAYGLIIAVVCGFVVYKLK
                     IQKGEGNLIKLIGICGVSTTVWGLIFGGILGDLIPIKALINPLEDVMTLMGMSLLFGI
                     IHIYVGLGIKAYTLIRSGKVIDAIFDIGFWYLCITGVCLLIIPFVAGDIGVFSEVGKY
                     LAIIGAIGLVLTQGRSFKGIPVKLFKGFSSLYGITSYFADILSYTRIMALCLTTGVIA
                     QVINLLGAIAGPILAVVIGVVGHTINLLINALGAYVHTSRLQYVEFFNKFYEGGGVPF
                     VPFKYKTKYTSINKKEM"
     gene            complement(40225..40536)
                     /locus_tag="ACGI5H_001429"
     CDS             complement(40225..40536)
                     /locus_tag="ACGI5H_001429"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9697140.1"
                     /translation="MAFEIIKSIVEAEQTADSIKVKAVTDAESIRADAVNKCESIFAD
                     VKKQAKLMEETLIEKAVTDSRAEVDKILANAKSECLKIEKTAEERKSKAIEAVIGKVV
                     R"
     gene            complement(41166..41441)
                     /locus_tag="ACGI5H_001430"
     CDS             complement(41166..41441)
                     /locus_tag="ACGI5H_001430"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Nif11-like leader peptide family natural product
                     precursor"
                     /protein_id="HFG9697141.1"
                     /translation="MNEKLTKILEEAKNDDEFRKELIKTREQRDVMDSFCKVVTSRGY
                     DMTVGELFSMGEEYTSNLLKSVNGGAAYPIEDWSDWYEDFFIMLSNI"
     gene            complement(41556..42965)
                     /locus_tag="ACGI5H_001431"
     CDS             complement(41556..42965)
                     /locus_tag="ACGI5H_001431"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009906176.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016740 - transferase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="L,D-transpeptidase family protein"
                     /protein_id="HFG9697142.1"
                     /translation="MIDGKEVKQESGQKNLKFKIAIVVGVLFVAYIGMAIFFRNHFYF
                     GTTINGVKASGKTVEQVNDLLTSSTNSYTLNLEERNNKKEQIKAKDIDLKFTPDDKVQ
                     KIKDSQSAIGWIGGIFKSKEYNNMITLSYNKDLLEKRFNALSCFDSKNVVEPKSAYPK
                     YDSTKNAYVIVPEVLGNKVKKDDFYKLVQNSINSGNTSISLDESKVYEAPNNTKDSEK
                     LKQAIKTLDKYVGVVVTYDFSDRKETLDGSEINKWLKVDSEKNYDITFDNDAMVEYTR
                     GLSKKYSTFGDSRPFKTATGKDITISGGIYGWLIDKKKEAEALVDVVKAGKNVTREPI
                     YIQKAVSRNKDDIGNTYVEISLSGQHMWFFKNGEMLVSTDVVTGDLARGFATPSGIYP
                     LNYKARNVSLTGQGYSSPVSYWLPFNGNIGIHDATWRNSFGGSIYKSSGSHGCVNTPF
                     SKAKKIYENIEPGTPIILY"
     gene            complement(43336..43998)
                     /locus_tag="ACGI5H_001432"
     CDS             complement(43336..43998)
                     /locus_tag="ACGI5H_001432"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439746.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0004826 - phenylalanine-tRNA ligase
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phenylalanine--tRNA ligase beta subunit-related
                     protein"
                     /protein_id="HFG9697143.1"
                     /translation="MIDISIDDKLKERWPNAKLGCIQAKVAVNKSSEKLINEINEFCD
                     TINQSLKVEDITKLDKIKDARNAYKELGKNPSRYRTSSEALVRRIIQGKGLYTINNIV
                     EINNLISIKSLYPVGTYNVSKLHSPVCFTVGDEGEQYKGIGKELINIENLPILSDSVG
                     KFGSPTSDSERAMITEDANEILICIFSFSQESDIEEYFGYAKELLKEYADGKDIETKI
                     IK"
     gene            complement(44252..46471)
                     /locus_tag="ACGI5H_001433"
     CDS             complement(44252..46471)
                     /locus_tag="ACGI5H_001433"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439757.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EAL domain-containing protein"
                     /protein_id="HFG9697144.1"
                     /translation="MTGRNKSFTLITILFLTSLFLTMGYIYIEDTKHLLMSEAKIHIK
                     EVAVQGSQLAQRQIEKDLDVLNIFSNYYASNPDIPNEEKMKNLLDEMENQKFYTMAIV
                     DINGNAENTKGDKFSVKDREFFKNSIKGKKYVSSPYVDEVNKSIKKIAISVPLLNNDK
                     VVGVLYCTYNINTLMKLINISFYENNSISYVVKNNGTIILHPQGDSLSKNIYKLLKQD
                     NDIQEVNRLKKELQENKTGATVLNMLEERRYLGYATMDNGNSENNYIKDWNLIFSIPE
                     TVVFSNSKQIINRAVYAVLSIVLIFIAIIFYIIYIKKSNEKEILSLAYEDKVTYIGNQ
                     NKFYRECSKYLLDKPSLNYIIVYFDINNFKMINDTFGYEFGDNLLITIAKALKEELTE
                     GEVYARLSSDYFAIFCDYKNGRNKIIRKLDNIRSNIESNLSIVFEISLCVGIYFVEEG
                     EVDIQKAVNKANMARSVAKGKNINYAIYNEDVRNKLSEESMILDDIKIALVKNQFEVY
                     YQPKFSLVTGEMIGSEALIRWNHPEHGFISPAVFIPIAEKSKLILKIGRFVFERVCND
                     LYEWKKQGKKIVPVSVNLSRVELYQPDIVKFINKTIKMYNLSSDFIEIEITETVAINE
                     LNILKNVLNELRTYGFSISMDDFGTGYSSISCLRDMPIDILKLDKSFLGGIEHDERSR
                     NIAKSIVSLAKSLDLVVIIEGVESKEQAELMKQFGCDLVQGFYFARPMPAKNFLDLL"
     gene            complement(46747..49401)
                     /gene="adhE"
                     /locus_tag="ACGI5H_001434"
                     /gene_synonym="adhC"
     CDS             complement(46747..49401)
                     /gene="adhE"
                     /locus_tag="ACGI5H_001434"
                     /gene_synonym="adhC"
                     /EC_number="1.1.1.1"
                     /EC_number="1.2.1.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422645.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004022 - alcohol dehydrogenase (NAD+)
                     activity [Evidence IEA];
                     GO_function: GO:0016620 - oxidoreductase activity, acting
                     on the aldehyde or oxo group of donors, NAD or NADP as
                     acceptor [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0006066 - alcohol metabolic process
                     [Evidence IEA];
                     GO_process: GO:0015976 - carbon utilization [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional acetaldehyde-CoA/alcohol
                     dehydrogenase"
                     /protein_id="HFG9697145.1"
                     /translation="MAHKEQVIIENKKENEVMSVGLDTVNNVESLVKKLAKIREAQKI
                     FATYSQEQVDKIFLAASLAANKQRVPLAIMAQKETGMGIAEDKVIKNHYASEYIYNAY
                     KETKTCGVIEKDEAFGMTKIAEPIGVIAAVVPTTNPTSTAIFKALLALKTRNGIIFSP
                     HPRAKNSTIEAAKVVLEAAVLAGAPEGIIGWIDEPSLELTTTVMKEVDLTLATGGPGM
                     VKSAYSSGKPAIGVGAGNTPAIIDDSADIKTAVNSILVSKTFDNGMICASEQSVIVLE
                     NIYNEVKKEFKERGAYLLDKDETEKIRNIILVNGGLNSKIVGQTACTIAKLAGFEVPV
                     DTKVLIGEVESVEIEEAFAHEKLSPVLAMYKASDFDDAVRKAEKLVEDGGFGHTSSLY
                     IDDVNQREKLDKFTSAMKTCRILINTPSSQGGIGDLYNFKLAPSLTLGCGSWGGNSVS
                     ENVGVKHLLNIKTVAERRENMLWFRAPEKVYFKKGCLGVALKELKDVMNKKRAFIVTD
                     TFLYNNGYTKAVTDLLDEMNIKYTTFFEVEPDPTLECAKIGAKAMREFNPDVIISIGG
                     GSAMDAGKIMWTLYEHPDVDFQDLAMRFMDIRKRVYTFPKMGEKANFVAIPTSAGTGS
                     EVTPFAVITDQDTGVKYPLADYELMPNMAIVDSDMMMNMPKSLTSASGIDALTHALEA
                     YVSMLATDYTNGLALQAIKSIFEYLPRAYDNGAKDPEAREKMANASTMAGMAFANAFL
                     GVCHSMAHKLGAFHHVPHGVANALLITEVMKFNSSDAPKKMGAFSQYKYPEALKRYAE
                     IASFLGLKGNSDEEKFQSLLVAIEDLKLKVGIPKSIKEFGVEESKFMDSIDEMVIQAF
                     DDQCTGANPRYPLMNEIKDMYLNSYYGR"
BASE COUNT        16699 a         8608 c         6121 g        18379 t
ORIGIN      
        1 ttaatacatt tttaagaatg acaaggaata aattataaca aattttagga atatataata
       61 atagggtctc agaacttagt tacaagttct aaaaccctat ttgtttagtg taaaaaacat
      121 cataaaattt agcttaaatc ttttcacata atattactct ttttctaagt gataataaaa
      181 tatatctatt cctctaaaaa ctgtaaaaat tcctgattaa atagtttaag ctcatcatag
      241 aatatagcat gaccactata ctcaaaagta tataaaattg aatcttctat tttttcattc
      301 ataaaaactg caaattcata cggacatatt tcatctaatt tcccatgaaa tataccagta
      361 ggcactctta cacattttaa atcattaaat aattcttcat ctcttaaaga tacagcagtt
      421 ccaatagtgc caatacctga tgcactaaaa ccaatatcat taaaccatct tctaaagctt
      481 tctggtggat ttgatgcaaa tactttttcg ccaaaatcgg ttaccatttc tggtctatca
      541 gtacatgctt gtgctatcaa tttatttaca tcttcacgtg tcataccata tggaaattct
      601 ggaggtcttt gtacaaatga tggtgcagca gctgcagcta ataccaattt tgacactcca
      661 tatccattaa ataaactcat atacctaagt acgattgctc ctcccattga aaaaccaaca
      721 agggtaaagt cttttaatcc aatagcatgt accaccttat aaatatcgtc tgctaattgg
      781 ctataagtat atcctcctga tgttgcatca gatttaccaa aacctcttaa atcaattgaa
      841 actgttctat atccgagttt tggcaatata tttgtttgat attcaaatat cttatgtcct
      901 aagggccaac catgtataaa aagtacagtt tttttagcac tcggattcaa atcatatact
      961 gctatgttta tatcattcac atatacataa tacatatcaa cagcaactcc cttcaagaaa
     1021 atgtatgatg gttattttat atatatgaat aaaatgatga ataactaaat tttcaaattt
     1081 atttacaata cttctctatt gccttttcaa ataaacttac atgaagtttt tcatctagga
     1141 ttattctatt taatatagct tttatataag ggtcttcaat aagacttata tctttataat
     1201 aattattaat agccacatgc tccaaatgca aatctagttt taatctgtta caaatagaat
     1261 ttccataaca tacaaaacca ccattccaat atgcaccaca agaacttgta gaacctctat
     1321 atacaggatt tccacccaat aatcttatag tctttgctaa tatctccata tgtaacattt
     1381 ctgttataga tatatttatc cacatttcac ttaactctct atgcgtttca tctaaatcaa
     1441 aattatggta tagatattga tttacactcg taaattcact tgatactcca gcatagtcat
     1501 ccatcaataa ttctgcataa tacttatttg gacctaaaac ttttatctct ggatatggct
     1561 catcacttga atatccattt cgcttgtgca tgtcataatg tgcaccactc ataatatctc
     1621 ctcctttaaa tttaatgtat gatattaatt gtatgcatca caactttttc atataactta
     1681 gataataaaa tctacttaaa taataaaaag ccatattaat taaaattaac atgacctttt
     1741 atccacaaaa ttacttttta attattcatc ttttccagct actgatagct ctttaataac
     1801 aactgaaggt gaacctatac tactcattgg aaattctaaa tcttctccta tagcttcaat
     1861 atctttcaac aggtcaaaat agtttcctgc tactgtaatt tgctccactg gaaatacttt
     1921 ttttccttct ttgatataaa agcccttggc agctaaagaa aagtctcctg ttactgaatt
     1981 tgcacctgaa tgaagtcctg caaagctagt aaccatcaat ccttcatcta tatcctttat
     2041 aatttcatct aaagatttat ctcctttctc tatataaaaa ttagttggat atatgcttat
     2101 aggtgatgaa tatgaagatt ttattccatt tcctgtagtc tttacacctg ccttattagc
     2161 cgtttttaag ttatgaagta aagttataag ctttccattt aaaacaactt cttttttaaa
     2221 tgtagctact ccttcatcat caaaaggagt agatgccata ccattttcta aaagtgggtc
     2281 atcaactatt gtaactatag gagatgctat catgtctcct tctctatttt tcaataaaga
     2341 taatcctttt tgagctgaat ctgcattaaa tatcccagaa aatgtgctaa gcaaagatac
     2401 catagcttca ttaagcaata tagttttata tttacctgat gtaatactct taccacctac
     2461 tttagataaa gcattatcaa caccaagttt tgctatctca caaggtttta tttcttcaat
     2521 agaatttgct atattatatc ctattccatc atatttttgt ccattgtctt ctatgatagg
     2581 aactacaaac cctataagca tattagtttt attgcttaaa ttaagacctt tagtattaga
     2641 tataccatta cttgatacag aataagatat agtacattta gataaattta ccaccttatc
     2701 tgaataagct ttagtctctc tttccatttc taaagctaaa tcaatcaact tatctgcctc
     2761 taaattttct agctctttag aataagtctt tacatcatta tagtgcttat ctccttcata
     2821 tataaattgt acatcttcat tttcaatagt gtttactcca tcttttacat tttttatcaa
     2881 catatcaaca gctttatcat ctaaaatttc tgtataagaa taacctatct ttccatttac
     2941 cttacctcta aaagataaac caaaagattt atcaagattg tatttctcaa cttctccttc
     3001 atatatattt atacttaaat tttctcctgt ataataatat atttcacact cttcaaaacc
     3061 ttcacttaga gcctttttaa ataatatatc tttaaaattt ttaagttcca caattatccc
     3121 tcctatcttc cacctacagt aatttctttt acccttatca taggttggcc tacattagtt
     3181 ggtatacttc ctgatgatga gccacacatc ccctgagctt gttttacgtt attcccaacc
     3241 atatctatat tcataagtat atcgctacct tttccaatta aactagcacc tctaactggc
     3301 tcttgtattt ctccattttt tattaagtaa ccttctgaaa ctgcaaaatt aaactctcct
     3361 gttacaggat ttacagaacc accacccatt tttttagcat aaagtccatc tggtattgac
     3421 tttataatat cttctggtct atcttctcca gcagcaatat aagtgttagt catccttgaa
     3481 gttggtgcaa atttgtagtt ttgtctacga gaacttcctg taggattcat tcccattcgt
     3541 ctaccattaa gtttatctat catataagac ttcaaaattc cactttcaat cagtatattc
     3601 ttttgagttg gatttccctc atcatctata ttcatagaac cccagtagtt tggtattgta
     3661 ccatcatcta tagctgtaat ctttgtggaa gcaatctgtt gacctaattt atctgcaaat
     3721 acagagttcc cctttgcaac tgatgtagct tccaaagaat gtccacaagc ttcatgaaat
     3781 attactccac caaatccatt atctattgct accatcatat tacctgcagg acaattttta
     3841 gcatgcaaca tagtatgcgc tactctagct gattcttttg cataatattc tgggtctatt
     3901 tcttcaaata tttcaaaccc tttacaacct ccaggacctt caaatccagt ttgattttca
     3961 ttacccttag atgcaattga acttatccct agtctagttc ttattcttct atcctcaaca
     4021 tatatacctt cagtgtttgc aattaatatt ttttggtctt tatccaaata actgacactt
     4081 acttgagata tatcattact aaattctttt gcactcttat atgcaacctt cataacactt
     4141 actttatctt tatttcctat tgaatttgga taaattttta tattatgtat gttatttatt
     4201 ttaatactgt catttaatat tacacttttt ccatcttcca atttacctaa agcaacagca
     4261 gctttgtatg ctacatccaa cagactattt aatgaattgt cacttgtata agcatatata
     4321 cttttcaatc ctttaaatat tcttattcct ataccataat ttcttccacc tattgcattt
     4381 tctactttat tatctattaa actaatagaa ttatttatag tgtcttcttc aaaaatctca
     4441 gcaaaatctc ctccagtaat tagacatttt tctaatacct tagaagctat attttttgaa
     4501 agcataaatt tacctcctac tttaaatttt taattaactt ttattcaatc tttttacttg
     4561 ttaacaaaca ttatatacta tattacttaa aataaggtaa ttatgaatat attatacata
     4621 tgttttatac taaaatgtta tcacatttta tctatacata cccatataac tagataatta
     4681 aaatgtataa tattatttgc tatagaaaat aatacactca tacataataa attttaggag
     4741 tgaagtatat gaatcaagaa tatgtaaaag gaaatcctat ttttactaat attaataaag
     4801 ttccaagaca atttccatac cttactgatg atattgatac tgatgttata attgttggtg
     4861 gtggcgtaac tggatgtatt tgtgcttact atctagctaa aaacaatata aagtctgtca
     4921 ttcttgaaaa aggaaggatt gcacatggaa gcactagcgt gacaacttct ctattacagt
     4981 atgaattaga tgacaatttg atagatttaa cagaggttat gactctaaaa gatgctctaa
     5041 aagcatacaa cctttgtact tcagcacttg aagaattaga tacatttata gagctatatg
     5101 gaaataagtg tgattatgcc aaaagagata ctctacttta tactgccaac aaacttgaag
     5161 ttaaggctat caaagaagaa tataacttaa gaaaagaaaa tggatttgat gttgaatata
     5221 ttgatgaatc cacaaaccct tttagctttg atttaaaatc aggattgata gcaaagaatg
     5281 gaggacgaga attagaccca tataaatata gtcaccattt gattgatgta agtttaaaaa
     5341 atggtcttca agtatatgaa aatacagaag taaaaaaagt agatttatca aatgataagg
     5401 ttactgctga agtatcgtat ggatacaaag ttcatggtaa aaaattaatt gtagctacag
     5461 ggtacaatac aagtttattt acaaaaagaa attttgcaac taagtcaaat acttttaata
     5521 tagcaacgaa accacttaaa aacatagctt cttggaaaaa caacatttta attagagata
     5581 actgtgaccc atataattat ctaagaacta ctaaagacaa tcgattaatt ataggtggtg
     5641 aagatgtaag ttttgatgat atagaaaatg aaactttagc caatgaaaag tatgatattt
     5701 tagaacaaag attgaaaagt atgtttaagg atataaaaga cattgaagtt gaatataaat
     5761 attgtggttg ttttgcttca actttagata atttaggttt tattggtcca gataataaaa
     5821 ataacaatct atggtattgc ttaggttatg gagcaaatgg tatactcttt gcaatattag
     5881 gaggtataat gttaagtgaa ttatatcttg gcaaacaaaa taaaaatatg aaattattta
     5941 aagtagatag atttgataaa tagatattat atattaaaag actgtaaaaa gatgaaactt
     6001 tataattcta aaagttaact ttgatacagt cttttataat gttcctttta aaaatacttt
     6061 atttataatt aaatataaag taaaatgtta aaatataact aataaaattt agtcataaga
     6121 taatatttaa gtttatttga tgaaatatgg aggaattatt atgaaggaaa tactcgttat
     6181 tgctcccact aaaggaacct atgaaaaatc aattcacata gttaaaaaaa acaaatatac
     6241 aaatattgat gttgtatttg gcaatctaaa agaaggtata cctcttgctg aaaaaagtat
     6301 taatcatggt actagaatta tcataagccg aggtggaact tacaatatgt taaaagctac
     6361 ttacaatata cctatagttg aaattaaagt agatgcttat gatattataa aaagctacaa
     6421 ggaggtaaaa aattccaacg aaccatttgg aataattgga tttaataatg tcatctacgg
     6481 tttcgatatt atagaagaaa tattgaataa gaaaataact atgattgaaa ttgaaaaaga
     6541 agaagaaatt tatgatgcta tagaaaagta cagaaagaaa ggtataaaca catatatagg
     6601 agataccact gttgcacata ttgttaagag acttaattgt aagggaatat taatcgaatc
     6661 tagagaagaa aacatactta gagccattca acaagcagaa caaatactcg aagcaaccaa
     6721 ggatgaacaa aaaagaagat tacagataga agctatgaca gattttgtac atgatggaat
     6781 aataacagtt gataaaaatt ttaaaataac attatttaat aagagtgctg aaaaaatatt
     6841 tggtataaaa aaagaaaatg cactttatca taatgttgta gatgttatcc caaacacagt
     6901 tcttccacaa gtagttgaga ctatggaacc tcaaattggt gaaatacaaa atatagggag
     6961 tacaaaaatt attacaaata gagttccaat aattgttgat ggtcagattc aaggggctgt
     7021 ttcaacattt caagatagca aggagataag ttcttttgaa catacaataa gaaggagctt
     7081 attaagcaaa ggtctatctg ctaaatacac ttttgatgat ataattcatg ctagtgaaaa
     7141 gacaaaagat tgtatagaac ttgcaaaaaa atatgcttgt tatgatactc ctatgattat
     7201 tactggagaa tctggagttg gtaaagaact attttgtcaa agtatacata actatagtaa
     7261 gcgtaaaaat gcaccttttg ttgctgtaaa ttgtgctgcc atacctccat ctctaataga
     7321 gagtgagttt tttggttatg aggaaggttc atttacaggt gctagaaaaa aaggtaaagc
     7381 aggtgtattc gaactagcac atgaaggcac aatcttccta gatgaaataa gtgaaatccc
     7441 tcttgaactt caaggtcgat tattgagggt attgcaggaa aaacaagtta tgagaattgg
     7501 tggtgataaa gttattccta tagatgtaaa aattatctgt gcttcaaata aagacttaaa
     7561 aaatatgatg cgcaatggtt tatttagaca agacctttat tttagaataa atatactaac
     7621 attatatctt ccttcattaa aagaaagaaa agaagatatt ataaaattat cagaattttt
     7681 tatacataaa tattcaagca aatacaataa aacgccttta attatcactc caaatattaa
     7741 aaaggcactt cttgaacgag aatatgaagg taatataagg gaattggaag gtatgatgga
     7801 aagggctgtt attgtggaat catttgactc gattttatta gaaaagctta gcaatgaata
     7861 tacaaataat atagttgata aagataatag tgattttgaa tgcagtaatt tagatttaaa
     7921 aactttagaa aaaaaatata tctataaaat ttataacgaa aataatagaa atactacaaa
     7981 aacctgtgaa attctaaaga taactcgctc cactctatgg cgtaagttaa aagaaataga
     8041 agatgatgtt taaaaataat acatatctat atatatcaaa acgttttatg tttaatttta
     8101 atacataaga cgtttatttg ttttcaataa aaaatacaat tatatgctaa aaagaatctt
     8161 tgtaagtgaa attctcgtca atcatacttt taattataag taatctacag catttcaatc
     8221 gattattaaa aataatcatg ataactaaag atacaaactc tatatattgg catagtaatt
     8281 gcttttataa tacctatata aaaatgaaag ggagtgatac tagatgcaca tcttaaaatc
     8341 agtgaaaaag ataccaggag gacttatggt ctgtcccttg ttattgggag cactatttaa
     8401 tacagtatgt ccacaagctc ttgaaattgg aggattcaca acatccttat ttaaaactgg
     8461 tgcaatgagt atacttgctc tattttgtct atgcaatgga gctcaaatca atatcagaca
     8521 agctggtaaa ccattgacta aaggtatagt acttacagca acaaaattta taattggtgc
     8581 agtattaggt attattgtta gtaaatttat tggacctaaa ggtataattg gtattacacc
     8641 tcttgccata gttgctacca tgactaattc aaatggaggt ctatttgctg ctcttgcagg
     8701 tgaatatgga gactccacag atgttggagc aatatctatc ttatctctaa atgatggtcc
     8761 tttttttaca atgcttgctt ttggagtaac tggacttgca aatgtaccta tagtagcact
     8821 atttgcagca cttataccaa tactacttgg atttatactt ggtaaccttg atgaagatat
     8881 acgagaattt cttgcacctg gtacaacatt attaattcct ttcttcgctt ttcctttagg
     8941 agcagcatta aactttaatc aaattataac tgctggacta cctggagttg tacttggttt
     9001 aggagttact ataataacag gtatgggtgg gtactttgta atgaaactta tacgtgcaga
     9061 acatccagca gtaggtgcag ctacaggtac aacagccgga aatgcagctg gtactcctga
     9121 agctttagca gctatagacc ctactctagc tacaatagca gctgtttcaa cagtacaagt
     9181 tgctgctgct attattgtta cagcaatatg ttgtccaatg ttagtttcct atctagataa
     9241 aagagaaaaa aagaaaaaat ctatttttaa aacaaataaa aatattgaag taaattaata
     9301 cttaaggagg taaaattaat gaatgcaatt attcatgcaa atgaaaaaga taatctagtt
     9361 acatgtgtca gacctttaat taaaggtgaa aaagtttcaa ttgatggaaa gtcttacata
     9421 gtaaatgata atatacctgt ctttcataag atggctacag aagatgtaaa aaaaggtgat
     9481 gttgtataca aatacggtga aattatagga attgcaacag ttgacataaa aactggtgac
     9541 tatgttcatg tacataacat tgaaagtaca cgtggtcgtg gagataaaaa ataggaggaa
     9601 gttaaaatga aattaatggg ttatttaaga gaaaatggtc agtttggtat tcgtaatcat
     9661 gttttaatta ttccaacatc tgtatgttca agtgagacag ctacaagaat agcatcactt
     9721 gtgcctggag caatagcaat ccctcatcaa catggatgtt gtcaaattgg ttctgatata
     9781 gagcttacag caaagacatt aataggattt ggaaaaaatc ctaatgttgc cgcagtttta
     9841 gtagttggtc ttggatgtga tggtattcaa gcaaaagaat tagcatctga aatagctaca
     9901 acaggaaaaa aggtaaatta cgttgttata caagaatgtg gtggaacatt aaaaacagtt
     9961 tctaagggag ctgaaatagt aagtaaaatg gctcgtgaag tatcaaaaga agtaagagtt
    10021 gaatttggta tgagtgaaat tacattagca cttgaatgtg gtggttctga cccaacaagt
    10081 ggaatagctt caaacccttc aataggcgtt gcatcaaacc ttcttgtaga tgaaggtgga
    10141 agtagcatac taagtgaaac tacagaagta attggtgcag aacatttgtt ggctacccgt
    10201 tttgaagatg aagaaatgaa agataagttt cttaaatttg taagtgatgt agaaaaaaga
    10261 gcaattgcta tgggagaaga tttacgtagt ggtcaaccta ctccaggcaa taaagctggt
    10321 ggactttcaa caattgaaga aaagtcactt gggtgtatgt ataaggcagg caataagcca
    10381 ttcaaaggtg ctcttgaata tgctgatatt gtacctcctg ataaaaaagg attatatttt
    10441 atggatactc caggtcaaga tatagattct atcactggta tggtagcagg tggtgcacaa
    10501 attgtaatct tttcaactgg tagaggtact ccaacaggaa gccctatttc accagttatt
    10561 aaaatcactg ggaatagtga tacatacaac aaaatgccag acaatatcga tataaatgca
    10621 ggtagaatta taacagatgg tgctaaaata gcagatatag gtcaagaaat atttaatgaa
    10681 ataatagaag tctgtaatgg taaacatacc aaagctgaaa gtcttggtca tagagaattt
    10741 ggcatttaca gaatttcatc tacattttag attgtaacaa aatatctttt ataaatataa
    10801 tacttatgta gatacataag ctaaaagttc tttctaatac tataaaaatt ttctatactg
    10861 aaaaggaact gtatcaaaat tattttgaaa acagttcctt ttttaacctc ttttactcaa
    10921 aatattataa aataagattt aaacaataaa cgtatcttga ttaatctcta agaagacata
    10981 aataaagcta aatgtaaagt gggataaata aaatttaata tctttgtatg aaaagatatt
    11041 tggtataata tgtctgagag aattcttatt tgtaaacaaa taaaggatgg aggatgaaac
    11101 aaaagaatga actttgaaaa cacaaaaaat aaaaaaataa tagctacttt actattgaca
    11161 ctccttttaa tcgtgtcatt aacatgtgtc acttttatta tgaatctaaa taaagtaaca
    11221 cataatgaaa cagaacgata tcttgtagaa gtttcacaaa gtatttccac tacaattaat
    11281 gtgaaatgta aaagtatatt taggacacta tattctatgg gagatactta ttttgagatt
    11341 aatgatagtg aaaaagaagt caatagatac ttatcaaaaa aattaaaatt atttgaattt
    11401 gattggttag gtattataga ttctaatgga aattttgtaa gtgcccttaa agatacaggt
    11461 aatgttaaag gacaagactt ttatagaaaa gcccttcaag gcaaagaaac aattactcct
    11521 gttaaatcac aatctggtac atatggaatt ttatattctg taccactata caatggtgat
    11581 aaaattgttg gagctgttgc tgcttggaat actattgata ctatgagaaa tttattaagt
    11641 gtagaaagct ttcatggtga aggattttcc caaattatcg accaagatgg aaattttatt
    11701 gtaagttcag caaacaaaaa tgctccaaaa aatgtggtaa atttttttga catgattaaa
    11761 caccaaggaa aacaggttga taaaaataaa cttgaagaaa tgaaaataaa cttaaaaaag
    11821 aacaaaactg gttctatgta ttatacatta aatgatggta tttctaaggc aatgcattat
    11881 cttccattac aagaagaaaa cttatacctc ctttcaattg ttccaacaaa aacagcaagt
    11941 gcacagtttg atttacttct aaaaaaagca atcttcatca atattttaat tgttatacta
    12001 tttttattgc ttattatatt gattatgttt ataaatcaaa agaacagggc acaacttata
    12061 aaaatcgcct atgtagactc tgtaactaaa ggttacagta aagcacgttt tgatattgaa
    12121 gctaaaaaaa ttatacagtc atcttcatca gaaagctatt cattggtatc tataaatatt
    12181 cagaaattca aacttattaa tgattctttt ggtagtgaag caggagataa aacattaaag
    12241 tacatacatg atgtcattag taattatcta gaaccaggag aattgctttg tcgagtttct
    12301 aatgaccagt ttaatgtact tattaaaact attcctcaaa aagaaattct taagtacata
    12361 gaaaatatca ccaatgatat taatagtttc aataaaaatg aagaatgtaa atattttata
    12421 gctctatcta taggtgtata taaaattgat gacccaaatc tacctttagt ttcaattcaa
    12481 gaccgtgcaa atgttgcacg aaaaaataat aaaggaaaca ttggaaatca tccactttat
    12541 acatgtgttt tttatagtga tttagagcgt ttaaaaatga ttaaagaaaa agaaatggaa
    12601 aatagaatgg aggaagcatt aaataataac gaatttatag tatatcttca gcctaaaata
    12661 agcctcaaag ataatactat tgtaggtgca gaagcattag taagatggca agacccaaat
    12721 aaaggtctta taccaccaga cgagtttatt cctttctttg aaaaaaatgg ttttattaca
    12781 aaactcgacc actatgtttt tgaaaaagta tgcagtatga taagaaaatg gatagataat
    12841 ggagaaactc caatacctgt ttcagttaat ttttcacgtg ctaatttaaa taatatagat
    12901 tttttagaaa aatacagaat gcttcgtaat aaatacaaca ttcctgctaa gctcttagaa
    12961 attgaattaa ctgaaacact tgtatttgaa aatctccaaa aattaattaa tataatagac
    13021 caaatccatg aagaaggttt tcaatgttca ctagatgact ttggaagtgg atactcttca
    13081 ctcaatatgt taaaagaaat aaaagttgac acattaaaac ttgaccgtgc tttttttagc
    13141 tcacctaatg cagataatat tgctgaaaat catgtaatag aatctatagt taatttggca
    13201 aaaaaattaa atatgaatag tatatcagaa ggtgttgaaa caatcttgca aatggattat
    13261 cttaaaaaaa ttaattgtga tatgatacaa ggatatgttt tttcaaaacc tctacctcaa
    13321 gaaatatttg agaaaatgac ttttggaaaa aaactagaag aaaccagtat ggatagttcc
    13381 gtttaaataa aataaaaaac ttgtctctat aaaataattt taatcatttt ataaagacaa
    13441 gtctttttat tttccaattt aattttattt tctaaatttc ttacactcgg cttgttttaa
    13501 attccctttt taagaataat aatacaatta tcatagcaat aaaatctgca actggctgtg
    13561 ccaaccaaac accatctaaa ttaaattgaa ttggaagtac aatgattaat ggtataaata
    13621 aaataaattg tcttaaaaga gttaaaaaca ttgaatgttt aactttactt atacactgaa
    13681 aatacacagg tcctacaata gaaatcccca ttataggcaa tgtaattaga tttaggctta
    13741 tacctcttac tgctatatcc atcaaatctg aatctttatt aaatatacct acaaatactt
    13801 ctgggaaaac ttgtactact aaaaatccaa atgacaatat gacaactgac actatgatag
    13861 ataatattaa agttttcttt gcacgctcat attgttttgc accataattg tatgatatta
    13921 tagtttgcat accttgattc aatccaaaca caggcatcat aaacatcaat aaaatagatg
    13981 taagtgctgt catagctcca atagctaaat ctccaccata aacctttaga gaattatttg
    14041 taaacatgtg agttatactt atagctactt ccatagcaaa aggtgtcatt cctattgcaa
    14101 ataccttctt tactatatct ttattcaatt ttaagttaca tttttttagt tttaaattgg
    14161 acttccctct tataaaataa tgtattaccc aaaagaatac tactatttga cagagtactg
    14221 ttgctatagc tgctcctttt atacctaaat taaatacaaa tataaatata gggtccaata
    14281 tcaggtttaa tacacatcct acaatcattg tccttgctgc taattttgga ttaccttctg
    14341 ccctaattgc attattaaga gaaaatgcaa ctaaattaaa tatacttcca accaatatga
    14401 cactcatata gtcttttgca taaaatattg aatctttact tgcacccaaa ataaaaagta
    14461 tatcttctaa gaaaactaat cctaatatag ttataattaa agagataatt atagatagtg
    14521 tcaaagcatt acctaatatc ttctctgctt cttctctatt tctttcccct aactttatag
    14581 acaatcttgt gctagcacct actgatacca acattccaaa agctattatt agagtaaata
    14641 ctggcatagt tacaccaaga cctgcaatag ctatagagcc aataccttcc atagaaccaa
    14701 taaaagctct atctactaca ttataaagtg aagttaccat cattgctatt attgcaggta
    14761 tcgaatacct aaataataaa atccatattt tttcatgtct taatgcttct tgattctcca
    14821 tgttgtcacc atttacacca tgtcataagt tatacaaatt ggtttatttg ttcttgggtc
    14881 tgttgctatt tctgcatcaa tattaaataa ttcttttaga ttatccttcg tcataacatc
    14941 atatgcatca ccttcacaaa ctattttacc tttcttaata cctatcatgt ggtcagcaaa
    15001 tcttgctgca ttattaagtt catgtattac catgacaata gttcttcctt gttttttatt
    15061 tagttcatct aataatttta gtatctccaa ttgatgtgcc aaatctaaat atgttgtagg
    15121 ctcatccagt aataatatat cagtttcttg tgccaaagcc atagctatcc atgccctttg
    15181 tctttgtcct cctgataaat cttccatatt tctatcctta aattctgcaa ttccagtaac
    15241 ttctaaactc caatttacaa tctctctgtc ttctttacta gaattaccaa atccactttt
    15301 atgaggaaat cttccataag aaattaattc tgaaacggta agaccactag gagcttgagg
    15361 gctttgtgga agtacagcca tatcttttgc tatttcttta gacttctttt tgtagatgtc
    15421 ctctccattt atatatattt tcccactatt agggctaata attctaccta tagttttaag
    15481 tattgtcgat tttccacaac cattagcccc tatgatggta gttatttttc cttttggtat
    15541 atttaaattt aaatttttta taatatctgt gtttccatat gatacattta gattcttagt
    15601 atttatacag ttcataacaa caccctttcc taatcattta ccaacattaa ataaataaag
    15661 tacggcactc ctattataga aactactata cctactggta tttctatagg tgctagaaga
    15721 tttcttgata tagtatctgc tattaaaagt aataatgttc ctatcaatgc tgatactggt
    15781 attaatcttt tatgctttgg tcctattatt tttctaccta tatgtggagc tattaaacct
    15841 aaaaatgaaa tactacctgc tactgctgtc gatacaccag ataaaattac tgcatatatt
    15901 ataagtcttc ttctttgttt ttctacatct acaccaagac ttatagatac ttcatcaccc
    15961 aaatttaaaa catctatata tttagattta taaatagtta tacccataaa aatcactata
    16021 aatggaagca cagctattac atatttccaa ctggttcccc aaatgcttcc tgatgtccat
    16081 gccataaccc tattaaattc ctgtgttgta aatttcaatt ggaatattgt caaaattgaa
    16141 gtaaaagcta tgtttacacc tataccaata agtagtaatc ttgatgaatt tataccacct
    16201 ttccatgcaa gagaatatat aagaaatgct ccaaataaag ctcctataag tgcaacaata
    16261 ggcattgtaa atacagtcaa gttactcata ccttcatata cattaccatt cataaggtat
    16321 atataaacta ctacaaacaa tgcagcacct gaatttattc ccaaaattcc agaatcagct
    16381 aaatcattct ttgtaactcc ttgaagtatt acacctgctg ttgataatgc agaaccaacc
    16441 aaaagtgcta ttactattct tggtaatctt aatttaaata ttgcaatttc atgattacgc
    16501 tgaccctgcc ctaaaaaagt ctttataaca tccattggtt ctatagaaaa tgagcccata
    16561 tttaaactca ataaaaaagt gataaaaata agcaccatta aaattgatat aacaagtaat
    16621 gttttagaat ttatttttat aatatttttc atagtaccta tttctccccc tttctaacaa
    16681 ggtatataaa tattggcact cctataagtg ctgttataga acctactggt gtctcatatg
    16741 gaggatttat catcctactt aatatatctg tatatacaag caatacagct cctaatacta
    16801 aagagctcgg tattatatac ttataatctg aacctactat tcctttagct atttgaggaa
    16861 ctataagacc tataaaaata atattaccag acactgacac agatgctcca gtcattaata
    16921 ttacaagtac tatacatata aatctaacaa agttagtttt ttgtcctaat cctattgcca
    16981 cttcttctcc aagacttaat atagttattc ttggagccat aataatagct aaaataaatc
    17041 caataccacc agctacaaat agcaatttta taccttccca cttcactcct acaagccctc
    17101 ctgatatcca gaaacttaat tgttgagata ggttaaaata catagatatt gctgatgcca
    17161 aagaaattag caatgtacca agagcgactc ctgcaagagc taattttaca ttattaactc
    17221 ttcctcttga tttagaactt ataaaatata taaataatcc acttatactt gctccaataa
    17281 atgcaaacat cattacacta aaacttccat gtataagttg aggaagtttt ttttgaagta
    17341 ccagtgatat cgaaattgcg aatgtagctc cttgtgtaat tcctataaca gatggttcag
    17401 ctataggatt tctcgttatt ccttgcatta ttgccccaga aactgctaaa aatcctccaa
    17461 caagtgcagc tgctattgcc cttggaagtc taacatcctt tactattctc atatttattc
    17521 catcttccat ttttatcaaa ctatctataa cagttgatag attcatatct tttgccccaa
    17581 tagttatgga taatacaatt ccaaatacaa gtacaactat acttactaat atcaacaaat
    17641 aagttatatt ttttttactc agcttagtca attatcctac ctccttttcc cttttaatcg
    17701 tcagtataat atcatctatt aagtatttta attttaagat ttattaaaaa taggtgtgaa
    17761 aaatgaatat cattatctca cacctactaa gttaagaatt actttgttaa ttcattttta
    17821 actgattcta ataataactc ttttccaatt ggattgtatg attgactgaa aaatggagca
    17881 gcatcaagta ttgttacatt accatctttt actgctctta tttgagccca gatagcacta
    17941 ttttctaaat cttttttatc tgcttctgta gcaattacaa ctatatggtc tgcatctata
    18001 tctgttaaac cttccatact taccattggt agtgttattc catcctgttt tggcatattc
    18061 ttaggtttag ctaatttcat atcatcattg attagagtac ctattccacc atcactaaat
    18121 accataaatt gacctgaact tgccaacact ggtaaataag ttttttctcc attcttttct
    18181 ataacttcct tacctaactt tgtagctttt tcatcatact tctgtagcca acttttagct
    18241 tcttcttctt tgtcaaataa ctttgaaaca tcagttaact tgcttctcca gtcatttgca
    18301 taatctttca tcataactac aggagctatt tcttttaatt ggtcatatat tttttcttgt
    18361 ctttgactca ttattattaa atcaggattt acttctaata tagcttccat atccatagta
    18421 tccatcattg agtgcccaac tatctttaca cctttaagct cttctcttat gtaacttggt
    18481 aatttatcag tttcatatga gtctacattt gctgttgcaa caggcttata acctgctaat
    18541 aatagttctt cactacttcc tgatatatca actatttttt taggatttga tggtatctta
    18601 acctctcctt taacagattg tacaactctt gtctctgatt tatctttatc ctctgtattc
    18661 ttatctgaac atgctgtaac aagtactaac gtagttataa tagatataaa tattgcaagt
    18721 gattttattt ttttcatgat tacttctcct acttgtttat tatacttaca tgatattgat
    18781 tatcataagc acatatttat tatagcattt ttctattttt agtcaatatt attttgtaaa
    18841 aggataaaaa ttcctaatta atcttaatta tatatagctt agataaggtt ttcttatatt
    18901 aaacagtatt tttttaaaga attggacaca aatacaatga cttttcagtt aaacaatgat
    18961 aaaatgcaat ttatagataa tgaatttagt aaggaggatt caaaacatgg tacatttagt
    19021 atattgtgat aatgcaggaa aaaaaggaga aaaggtctta gataaaatct tggctggaac
    19081 aaaaacaatg gttattagag gtgctgctgg tagaaaaata ccacatagta gagtatttga
    19141 agatgagtta ctttatttta tggaaaaagg aactgcaaaa atatctgcaa aagccactgt
    19201 taaaaaggta gaaaactatg ttaaattaac agaagatgaa atttctaaaa ttttaaatga
    19261 aaatcaacca aaattaaatt tatctgaaaa gcaaaaagtt cgttggcata aaaaatgttt
    19321 atgcttagtt gaatttgaaa atgttgaaga aataacacct cttgattttg accatcaagg
    19381 aaatatggat gattggctta ttgttgaaaa aattgaagat gtagttgttg gtactagtat
    19441 accttacaat tatgagaagt ctaaatttta aagtatcaat aacataatac tatattgcta
    19501 aactctactt aaataaaaaa agagtgcatt taataattat aaaaattatt tttatacact
    19561 cttttttaat aataatttta aattacttac tttctaatct ttcatataca tctataaatt
    19621 cttctgctaa ttgttgaaaa ttcatagctg tcattaaatg gtcttgtgca tgaataagta
    19681 taacacttat ttcagtttta ttaccattag cttcattttg tatcaattct gtttggaatt
    19741 tatgagcttt atgaattgat tctttcgact tttcaataca ttctctagct ttatctatat
    19801 tcccgctctt tgcttctttt attgcttcaa atgctagccc tttcgcatca cctgcaaatc
    19861 caattattcc aaaagatatc tctatcatct tctcatccat ttattcgacc tcctaaatat
    19921 ctctatagct tgatatgact aatccattct tttctaaaaa ttctttgact tttttagatg
    19981 taagtatctt gtgctctttc gttctatcaa tagcataaga tgtagaattt aaaatataat
    20041 catctaaaaa agctgggtga gacataatat ccactacatc atacttcatt atttcgtcta
    20101 tattttttat aaaatattct tcacttacat tttccttata aaaactatct attaaaggaa
    20161 ctactttaga atactctaaa ttatattcaa atccacctct tattggaaga ttatacttgg
    20221 ttacaatctt ctctattact ggctttaaac ttaataaagt atggatatga tggtgactat
    20281 ctaaatgaga tatatctatt ccaagccctt ttaccctatc tatttgagca caaagttctc
    20341 tataaatctc atcacaatcc attttttcaa taatttcgtc tgtaatcctc ctaataaaaa
    20401 aaccgtcttt atcaacaata gtttttaagt tagataataa tggtctacca caacttaaag
    20461 tcatatgaac tccacaattt aaagttttat tttctttaag taagcctact ccatgttcta
    20521 ccccaggcat atttgccatc atagaagtag acctaactat accattatta tgagctgaaa
    20581 ttattccata gttcacagct tcacaatatc caaaatcatc tgcatttatt ataattttag
    20641 tcataccata acctactttc tatagacaac tatctattaa atctaggaag ataatcttta
    20701 tgagcttcca acatttcgtc taatatagtt tttgctaagt catcagatgg aatcaatggg
    20761 tttatacaaa gtgccaaaag agcagattca taatcgccat atacagctgc tttagctgcc
    20821 aatacttcaa atgatttgat ttgacttact aatccatgca cagaatctgg taaatatcct
    20881 atacttattg gttttggacc attttttgtt attacactac ttacttctac cgcttgttca
    20941 tctttaaaat ctcttataga acccttattt aatgtattaa ctacttggat atcttttttg
    21001 tcgttgtata tagaacttat taaattacaa gcagcatcac tatagtaagc ccctcctctt
    21061 ttttcaagtt gaggtggttt tacatctaat ttttcatcct tatataattc aaataattgt
    21121 tcttccaatt ctttaactac ttgacctcta gcttttccct ctttaaactc tctcaactca
    21181 tcctcaagca tttctttagt tttatagtag tatctatgat atggacaagg tattgcaccc
    21241 aaagatttta caaattcagc attaaaatca attgccttta tattttgcat acttatatct
    21301 gctttgacaa atttatcaat tgcttctttt gtaacatctt ctccatctaa agatacattt
    21361 agaccataaa ccatatgatt aagacctgca aaatccatac ttattctgtc actttctaca
    21421 ttaaatagtt tggcaacatc attttttaaa tgaattggca cgttgcatag acctatatat
    21481 cttctaaaat tagtatattt gaatacagcc tctgttatta ttcctgttgg atttgtaaaa
    21541 ttcaccatcc atgcatttgg acataattct tccacatctt ttattatatc aaatataact
    21601 ggtattgtgc gaagggcttt aaataaacct ccagcaccat tagtttcctg ccccataact
    21661 ccatgagata aaggaatagt ttcatctttt attctcgcat ctaaaagacc tactctaagt
    21721 tgtgttgtca caaagtctgc atctcttaga gcttctcttc tatctaaagt aagatttatt
    21781 ttcatatcta ctccagcttt ttttaccatc ctcttagcta gatttccaac tatctctaat
    21841 ttttcttttc cagcttctat atctacaagc cataattcct ttacaggtaa ctcttcatat
    21901 ctatttataa aaccctctac aagctcagga gtataacttg aacctcctcc aattgtaact
    21961 atttttagtc cctttttcat ctcattatac catccttacc tataatttaa tatactctac
    22021 aaaaccccat acatttattt aaaactctat acatttattt accgaaataa aactacctag
    22081 ttgttaattt tcaatttatt agcttccatt ttttcagacg ctatgacaaa tggaatatat
    22141 attaatattg ataatattaa attaaatagt gctaaagctc caccagtcca gtcacctgta
    22201 gccattgctc cacctaatat aggaggtgtt acccaaggta ttttaggtaa aattactggt
    22261 gctactaatc caaaatctat tgctaagtat gatacagcac tacatattac tggtgcaagt
    22321 acaaatggaa tcataaatat aggatttaaa actattggaa gtccaaatat caatggttct
    22381 cctatgttaa atattgcagg tggaccacct aatactatca tctctttacg tcttcttcca
    22441 gctattaata aagctactat taatcccaat accattccag aaccacctaa atatacaaat
    22501 gcatcaaaga atgcacctgc aagtacatgg tatccttccg ttgctcctgc ttgagccaag
    22561 gcagcatttt ctccacctaa tttcataagt atagtttctg taaaaggaag tgctatattt
    22621 gcaccatgaa gtccaacagt ccaaagtata tgaattataa atgcaataag cattgtagaa
    22681 cctagactat cagctacatt tgatagtggt gctcctaaat aagtatttaa aatatctgtt
    22741 aagaaacttc cattagaaag catttttata aatattccta ttacagtaaa tatcattata
    22801 gttaacattc ctggtattaa ctttgcaaat gatcttgaaa ctgctggtgg aactccatct
    22861 ggcattttta tagttaattt ctttacctta gataatctta caaatatctc agttgataat
    22921 aatcctatta atatagaaga gaataaagct gctgtaccta agtaggtttg ttgtatcatt
    22981 ccccatcctt caactactgt agttcctccc tcaggaacta ttttaccaat ttgtggagcc
    23041 attataaaaa agatagataa agctataagc ccagattgta acccatcact ctcataagat
    23101 tttgctagaa aataagcaac acctattact aagaatactg ccattgtacc tattgctccc
    23161 caccaaaggt cgcctccaaa tgtggtccag ttttctccaa atatacttgc catcaaattt
    23221 ttgtatgctt ccaatggtaa gttatttatc aatgttccca atgcacctac catagttata
    23281 ggtatcatta ctataaatgc atctcttact gctactaagt gcctttgagc tcctatttta
    23341 gcagctacag gcactatata tttatccata aatgacatga atttttccat tttacatcct
    23401 ccagtacaac tttattttga actatttaac tctacagctc tatctaacac agcttttcca
    23461 ttacatcttc cataatccat catatttata acttctactg gaatattata tggttttgcc
    23521 atttcagttg cttttcctaa tacatatcta acttgaggcc ctaaaagtaa gacatcacaa
    23581 ttttctattt cattttttaa gttcacttct gatatagccc atatttttgc ttctataccg
    23641 ttttcctttg ctgcatcctc catttttgta actaataaac tagttgacat tcctgctgaa
    23701 caagctaaca ttatttttat cattttttcc cctccaaatt agattcatta aatatttttt
    23761 aagtcataag ttttttaaac tatacattta aaatatgttt ttctattaat tttttcttaa
    23821 tgtatatatc ttatttttaa atgtatatac atttaattct tgatattatt atataccaaa
    23881 tgtatataca tttcaagaaa actttttcat tttatttaaa ttttattcga caacagcatt
    23941 caaagttaat gtatatccat agtgatatgt gtgtgagtac tcaaaaatct cactattttg
    24001 taacttacaa atttggctta tatataaaag tggctctggt tcttctaatt ttagattatc
    24061 catacactct tcattcgata ttacagcttg tacttctctc tctgacatgg ctatcttgta
    24121 tccacacact tcttcaacaa aattataaag agaattttca caatgagtct tatttaaatt
    24181 tggaaataac ttaactggca tataagtaat catatatgaa actcttacat cattagctaa
    24241 tcttactctt tttatttccc aaacattttc ttctaaactt atattcaact tacttgataa
    24301 attttcatct gcctgaacta tttcaagaga taccaatata ttagatactt tatagccttt
    24361 actttccatc tctttagtaa atccacttac agacgatata ttatcatata tattatttgc
    24421 aataactata ctacctacac ctctttgtct agttatatag ccttctttaa ctagattatt
    24481 aagtgcagac cttacagtca ttctagttac attaaattct tcactcagct gtttttcaga
    24541 agggattaaa tccccttctt tcaaactgtc tgaatttatt aactctctaa catgattttc
    24601 tataacttta taaattggct ctttcattta attcactcct tattaaatct tttatataat
    24661 aagataattt tatatacaaa caaagaaaat gtctatacat ttaagataat ttaaatttta
    24721 ttcagaaatc ttgtacaact ttccgagttt taataaagat ataaatagac ttatcattaa
    24781 tatacctttt aatatacttg ataaggttat actccaccat acaccattta gacccaacat
    24841 ttctggtcta gatataaagt aagccaatgg tactcttgca ccagtcagta tagtaattat
    24901 aatagaaggt atataggttc tccctaatcc tttgaaagct cctgttgtta ttatttctaa
    24961 acacataaaa aattgagaat agcctaatat tttaagataa actgctcctt tttctattgc
    25021 ctcactttca tctataaaaa tagaaaatat actctctcct gcaaacacta atactaaagt
    25081 agttattata ccaagtacag aagatacagt tatagctatt ttgcaacctt tatttattct
    25141 agaatacttc ttggcaccat aattttgtcc aacaaaactg cctaatgcaa ctgatagccc
    25201 ttcagccgtc atccaggaaa ttgcttctat ttgtgagcct actttttgta ctgcaacagc
    25261 cacaggcccc catgatgcta ctattactcc taatagcatt gagaatactg taaacatacc
    25321 actttgtatt gctataggta atcccaattt atacagaact ttataatatt tagtctctat
    25381 ttctttaaat agtcttaatt taaaatattc ttctttactt ttaactatta tatatataaa
    25441 acatgtagta actactatct gagcaaatac agttgcaata gcagctcctg caacaccaag
    25501 ttttggagca aatccccatc caaaaattaa tatagggtca agtataatat tagttattaa
    25561 tcctactgta ttaatacgaa aaggagtttt actatttcca agaccattga aaattgcagt
    25621 aaatactgga ttaataaaat aaaataccat acctagagct actattatca aatactgtct
    25681 agacatggtt ataacttcta agtctcctaa tctaaaaaaa cctatcaatt gtttattaag
    25741 tactattaaa gaaattgtat atattattgc tagtataata tttatttcta ttgctgactt
    25801 catatatgat ttagtagtgc ttatattatt tgcaccaata ctttgtgcta cttttatctc
    25861 tccacctact tttgaaatca taataaatgc cattgcaagc catggaaaaa aaccagctgt
    25921 tccaactgca gctactgctt tacttccggc tttaccaacc catatcatat ctatcatgtt
    25981 ataccccatc tgtataaatg aagtccccat tattggaagt gatagcttaa gtaatttttc
    26041 tgtaattctt ccttctgtta aattaagtct gtctttcatt ttccacctct tttatattaa
    26101 atttatttgc ttatatagct agattaatca ttttatttga ttgagttcac tatccttcaa
    26161 tttatattat catatctcag gattgcatct caatcatact tatgtttaag atacagtatt
    26221 ttacctatct atgataaaat taatacttat gaatataaat ctagccattt catcaataca
    26281 tattctaacc tttaacttaa cttcaattaa gtatacatat cgtaaccaat tagaatattt
    26341 tatacggtat cttccattaa taaacaacca atatcaatga tttatatata attttattta
    26401 tacataaaat agtatactat aataataaaa aaactatatt tgaatgcttt aagcatgttt
    26461 actaattgta atttccacac aaatttgata atatatgaat atattatggt gaaatttata
    26521 gatatatatt aattatgggg agattgtggg aggttctttt cacaagacat ttaagctatg
    26581 aaaataaata aaaaattcaa tagagttgat atgcaggttt caatacttac tgcaattatt
    26641 gtaataatat cttcctcatg tgtatatttt tttaattata cactaactta taagagcatg
    26701 atatactctt taagtgagag gtcaaaacat atctatgaat atgtagaaag aaatattgat
    26761 aaaaatacct ttactgaaat taattctaaa gaagaccaat caaaaaagtc ttataaaagt
    26821 tctaaaatcc ttttagaatc tgtaaaaaat actactggag tcatgtatct atatactgct
    26881 aaaaaaacaa aagatggatc actagtatat gttgttgatg gtttaaattc atctaggagt
    26941 gattttagaa atgctggtga tttgatagaa aaagagattt ggggagacct taacaaagca
    27001 ttagataatc atatattgtt acctaaaaag attaaatcaa catcttgggg atacatattt
    27061 atatcgtatt ttcctattca caatgatgtt ggtaaggttg ttggagtaat aggaattgaa
    27121 tttgaagcaa aacatcaata caatacattt aaatttataa gtatagttac accaataata
    27181 gcattattaa cttgtctaat atcagcattg attgcagtga ttctatttaa aagaatatct
    27241 aatcctacat atactgattt tgctaataca gattatttaa caggcctaaa aaatagaaat
    27301 gcttttgaaa tagatatgaa taacttaaac aattcaaatc taaagaatct aatatctatc
    27361 atatcaatag atttagacgg tttaaaaaag attaatgata aatttggcca tcagacagga
    27421 gacttatata ttaagcaagc aagtaaaatt atacaatatg taataaataa aaaatatata
    27481 gtttatcgta ttggaggtga tgaatacata attattctaa aaaatttatc tcacaaagaa
    27541 ataaataata ttataaataa tattaattta aaaatagttg aagaaaactc aactaatgaa
    27601 ttaaaattat caatgtctat tggatatgct atttttgatg aaaaagtaga tgtttcttta
    27661 tttgatacat atcgtcgtgc agattctcaa atgtatgata acaaaaggaa aattaataaa
    27721 caatatcaat aataaattta aaaagtctat tctttaaata ataaatcaca agaatagact
    27781 tttttaaatt tgtgttttta taagataaat tatttaatta aagtttgttc ttttttctaa
    27841 acgattcttt ataaattcat atattacttt cactaatata tttgtgacta atattaacac
    27901 agctagtgat gctgcctgtg cagtactccc cttatcatct agttgtacaa ttgatattgc
    27961 agctactttt gaacttgcag tatatataaa aactaatgct gatattgtca ccatggagtt
    28021 taggaaaaag tacataaagt tctctaaaac tgctggcaaa caaagtggta tagttacgtt
    28081 cttaagaatt gatgcgctgt ttattcccat tgatttagct accatatcca attctttatc
    28141 tactttctta atagcagtag tagctgttat aaatgctact gaaaagaaat gaactatatt
    28201 acatataacc attataagta atgttccata taatccatta aacaaattct taatgtatat
    28261 tgtatccata aaattaaact ctaatttatt aaaaaataat acataagcta tacctaaaac
    28321 taatcctggc aatgccatag gcaatgtact taaaaaatac ccaaatgatt ttaaatatgg
    28381 agctttttct gttttttcat tcaaatatgc aaataagaaa acaaagctcg tccctagaat
    28441 agctgtcaat agtgacattt ttattgaatt tataaatggt ttaatcccat caatactgtt
    28501 tttcatagaa aaatgttcca gtgtcagtct taaatcatat ggccaaactg atattaatga
    28561 agataagatt acagttaaca ttacagctat tataccaaat gcaataattc ctacaacccc
    28621 tcctaaaata ctatctctta acttattagt tttaacctta tatggaattg actttgaagt
    28681 tatatatgaa ttttgatttt tttcaatttt tttagttact ataaacgata ttattgcagg
    28741 tattaaaagt aatattgata cagttgctcc cattggcata ttctgttgcc ctataatttg
    28801 cttatataca tctattgata atacattaaa ctctcctcct atcacctttg gagctccaaa
    28861 atctgtaaaa cataatgtaa acgatacgaa tgcagaactt attaaagagt attttatact
    28921 tggtattgtt atgcttataa attctcttat cttgcttatc cccatagtat tactagcttc
    28981 atatagtcta taatcggttg aacttagaga tatataaagt atttgaaatg attgaggaaa
    29041 tacatatata atttgtgcca atattattcc cactgctcca tatattggaa catgcactcc
    29101 aagtaaatta gttaccaaac cttgatttcc aaataaatat actagaccta ttgcatgcat
    29161 cattgttgga gcaaacatag gaaacatagc taatgattta aaaaaacctt taaatttaat
    29221 ctttgttcta gttaatgcat atgcatatac taatgcaagt gttagtgata ttacagttga
    29281 tataactgat acaaatactg tattttttag agaatttaat agagattcag aagccaagta
    29341 ttcttgaaag ttttgtaatc ctacaaagac tccatcttta tctaaaaaag cctgtacaaa
    29401 tagatatatt ataggtgcta ataaaaatat tactaaagac ataactaata ctgtaagcat
    29461 acattttttt atatctaaat tcatttttga tttaagactt atacttttag aacttatagc
    29521 attattattc atacacttat gctcctttaa cttttggata ctttaaatag tatttttcgt
    29581 ctatacttat ttttacaagg tcaccttcta ctaaatttaa attaacccac tcttttatag
    29641 aagcatcact tattatgaaa ttttcattta atttatcttt tatttcaact ctcaataaat
    29701 tccctctaaa ctctatattt gatattattc cttggtagtt ttcttttgtc gatttctcta
    29761 tttgaacata ttctggtctt acagttaata tagaatctcc attatcaaaa cagtttgtat
    29821 ctcctataaa ttgagctgta aataggtttt gaggattttg gtatatttct tctggagtcc
    29881 ctatttgcat tatatctcct ccatttagaa tagctatttt atctgccata gttatagctt
    29941 cttcttggtc atgtgttacc attattgtcg ttatattaag ttctttttgt aatcttttaa
    30001 tgtccattct aagcttgtgt ctaacctttg catctaatgc ggacattggt tcatctaaaa
    30061 gtaaaaactt tggttcaaga gctaatgctc ttgctattgc aatcctctgt tgttgcccac
    30121 ctgataatgc tttaggatat ttatgagctt cattagtcaa tccaactgtt tcaagtactt
    30181 ccttaacttt attatctatt tttccttttg aaacttttct ctcttttagt ggaaaagcta
    30241 tattgttata agcagtcata ttcggaaata atgcatatga ttgaaatact ataccaaaac
    30301 ctctctttga tggctctaaa tttgtaatat ctttatcctg gagaattata gttccgctat
    30361 ttacatcttc aagacctgct attattctaa gtaatgtagt tttaccacat ccactaggtc
    30421 cgagtaaaca tagaaattct ccttcttcaa tatccaaact aatattattt aaaacccttt
    30481 tttggtcata acttttaaac acattattta tttttaagta actcatatct tatctctcct
    30541 tatatagtta tttttttatt ttaaatttta tatcctactt tttcttctaa aattctttca
    30601 tctaaattat taatttaaac tttacttact ttcagatttt gaaccgtatt ttgattccca
    30661 agttttaagt actgtacttc tgtttttggc agcagagttt aaatcaactt cttttataag
    30721 ctgttcaaat ggttgtttag aataaccttt tggaactgga ttatctgtct ttatggaagt
    30781 aactgctact tcatgtgcat atctatccat agctgaatca cttattgccc aatctaaaaa
    30841 tagctttgct tcttttttta tattatcttt tttaactaag gcatttgctt ctaagtccca
    30901 gcctgaacct tcctttggaa atacaacctc tataggttct ccactagata attgttgtgt
    30961 agctctatat ccaagtgtaa tacctattgg atactctcca gagccagcta acttcgcagg
    31021 ttttgaaccc gagtgtgtat atgtggctat atttttatgt aatttatcca tgtaattgta
    31081 agcatctttt tcacccatca tttgaataag ccctgatact gtaagatacc ccgttccaga
    31141 tgatgctgga tttggcattg ttataagtcc tttatattct ggttttatta aatcttcata
    31201 actttttgga atatctatac ctagtttctt aagttcctta taattaacta ctattgctgt
    31261 ctctgggaca ctcattccta cccaagatac atcatcttca gtatctttaa attttttatc
    31321 aactttatca taatttttag gcttatatgc ttcaagtgca ccatcttttt ttagctctat
    31381 catgttcatt gctgataatc cccatataat atctgcttgt ggattatctt tttctgctaa
    31441 tagttttgaa gctattacac catgagaatc cataactatc tctacatcta tattgggata
    31501 ctcttctcta aaaccttcca tataataagc tatctgctct tcctctagtg ctgcatatat
    31561 tgtaagttta ttatttcctt ttccttgagt agtttgtggt gttgttgata tgcaacttgt
    31621 cataaatgta atcactacaa tgcacagaca agtaaatata aattctttca tatcttcccc
    31681 ctttgtgttt tttccttttt ttatttgttt tttattgttt ttgcttatgt ttatataata
    31741 cacctaattt gttaatataa agttaagtgt aaattaacag ttcgttaatt tttagaaatt
    31801 tttgttaaat atattatttt tagttaaata cagtctgttt ttaaacaata tattaatttt
    31861 tatagtatct acattttaat ttaaacataa aaaataagtc taacctctat aaagtagaat
    31921 gttagactta tttttataag tatttaatta tacaaccaaa tcattttttt tcttttcttc
    31981 aagtgctttt ttaagcacca tatccttaac cttcataagt ctagtagtac ttgctctctc
    32041 attttcttca agcttcatag ctatatactt aatagtctca atgtaatttg gtatcattac
    32101 attttcaaga gcattaacac gtctacgtgt cttttctatc tcttgtgcaa gaagctgtgc
    32161 acttttttca ctttctgcaa gtcttaaaag tggttgcata gcatctgaga aagcttccat
    32221 agcagaatct aattcacctg atgtaaaagc aagaccataa ggataaatat cactttgatt
    32281 gttttcagtt ttaaagtcaa acacaggaac atcaacactc attatatttc tcgtagaaac
    32341 atctactgaa actgattgct ttggcatcat aagtgctgaa cccagatact cctgactcat
    32401 aactgctctt gcgattataa agtttttata agcagtatca agagcatttt ctgcttcttc
    32461 acgcaatcgc ttattttctc ttacaatctc aagaaattgt ttcataagtt catcaagttt
    32521 atctttaaga agcttatgac ctcttgtagc agttttaagg agtttcttaa gtctagtcat
    32581 ttccatacgt gttggattta tatttaatct agccacagat atcactcctt aggcatatat
    32641 ttttcaaaat attcatcacg gatacgttta agttcacttt tgggtaacat actaagaagc
    32701 ttccatccga tttctaatgt ctgctcaata gttctatcag ttctaaatcc ttgtgaaaca
    32761 tattctttct caaattcatc tgcaaactta gcatacatta aatcaatctc agaaagtgca
    32821 gattcaccaa gtatagccat aagttctttt gcatccttac ctcttgaata agctgcaaaa
    32881 agctggttca ttgtatctgc atggtcttca cgagtcttac ctttaccaat acctttatct
    32941 tttagacgag aaagtgatgg taaaacatct ataggaggct gtatatcttt tttataaagt
    33001 tcacggctaa gtataatttg cccttctgta atgtatcctg taaggtcagg aattggatgt
    33061 gtcttatcat cctcaggcat tgtaagtatt ggaatcatag ttatagaccc ttcatgccct
    33121 ttcatttttc ctgctctttc atacatagta gcaaggtcag tataaagata tcctggatat
    33181 ccacgacgtc ctggaacttc ttttttagct gctgaaactt cacgcaacgc ctctgcatag
    33241 tttgtaatat ccgttattat aacaagtaca tgcatatctt gctcgaaagc aaggtattct
    33301 gctgctgtaa gtgccattct aggtgtagat acacgctcta cagctgggtc atttgcaagg
    33361 tttacaaaca ctacagaacg gtcgattgca ccagttgctt taaaatcgct tataaaaaat
    33421 tcagcatctt caaaagttat accaactgca gcaaatacaa cggcgaactt agaatcagtt
    33481 ccacgtactt ttgcctgtct tgcaatctga actgcaagat tggcatgtgg caaaccagac
    33541 cctgagaata taggaagttt ttgccctcta accaatgtat taagtccatc tatagcagag
    33601 actccagttt gtataaactc ggccggataa tcacgtgctg ctggatttat tggagctcca
    33661 tttatatcaa gtcttttatc tggtataatt tctggacctc catcaatagg tctacccatt
    33721 ccactaaaaa cacgacctaa tatatctggt gaaactccaa agtcaagact ctttcctaaa
    33781 aaacgaactt tactttcagc aaggtttata cctgttgagc tttcgaaaag ctgaacaagt
    33841 gcagtatctc catttacctc tagaactttg caacggcgaa tttctccatt tgaaagttca
    33901 atttctccaa gttcatcaaa ttttacacct tctacgccgt ttattaacat aagaggaccg
    33961 gctacctctt gtattgactt atattccttt atcatagttc ttcagccccc ctctttttaa
    34021 taaggtctgc aagctcgtta tctatttcat cttcaattga atcgtaagct gcatctatat
    34081 cgccttcttc tacatactta gcacgaccaa tcttttcaag aactgaaagc ttgataatat
    34141 cgtttatagt aacattttgc ttgatagcat cttgtgctga cttatagaat tttaatataa
    34201 gtcccatcat tctatattgt ttatgaagtg atgtataagt atcaacttca tggaaagagt
    34261 tttgatgaag gaagtcttct cttatagaac gagtaacctc tagtatcaat ctatctccat
    34321 ctgaaagtga atcaacccca accaattgaa ctatttcttg aagttcagat tcaacttgta
    34381 aaagtttcat agcttgagct ctttgagctg agaaattatc atttacattt ttatctgccc
    34441 atacatcaac tttttcctga tagagtgaat aactagtcaa ccagttaatt gctgggaaat
    34501 gacgtttata tgctaaagat gcatcaagac cccagaatac ttttactata cgaagagttg
    34561 cttggctgac aggttctgat gtatcaccac caggaggaga aactgcacca attgctgtaa
    34621 gtgttccttc tctttcatcc atacctagac aatttacctt tcctgctctc tcatagaatt
    34681 gagcaagacg tgaacctaag tatgcaggat aaccttcttc accaggcatc tcctctaaac
    34741 gaccactcat ctctctaaga gcctcagccc atcttgatgt agagtctgcc ataagtgcaa
    34801 cactatatcc catatctcta aaatattcag ctattgtaat accagtgtat atagaagctt
    34861 cacgtgcagc aaccggcata tctgatgtat ttgctataag cacagttctt tgcataagtg
    34921 actcgcctgt tcttgggtct tttaattcag gaaattcaag aagaacatct gtcatttcat
    34981 ttccacgctc gccacagcct atatatacaa ctatatctgc atctgcccat ttagcaagct
    35041 gatgctgtgt aacagttttt ccacttccaa aaggtcccgg tatagctgct accccacctt
    35101 ttgtgattgg gaaaaatgta tctataactc tttgacctgt aacaagaagt gaatctggtg
    35161 ttttcttttc tctatatggt ctttcttttc taactggcca tttttgcatc atagttacag
    35221 gtatatcatt acctttttca tctgtaataa cacaaactgt atcttcaaca gtaaattcac
    35281 cagaatatat ttcttttata gtacccttaa ctccataagg aaccataatt ttacattcta
    35341 ctactgctgt ttcttgaacg ccaccaatta tatctcctgc tacaacctta tcaccaacag
    35401 attttttagg tttaaattcc cacttagttg ttctatcaag tgaagatact tcaacacctt
    35461 tagttatatt agtacctgaa atatcataca ttttttcaag tggacgttga ataccatcat
    35521 aaatagttga aataagacct ggtccaagtt caacactcat aggcattcca agagaaacta
    35581 cttcttcccc tggtcctaga ccggaagttt cctcataaac ctgtatagaa gctttatctc
    35641 catgcatttc tataatctcg cctataagat gtttatctga aactcttacg acgtcaaaca
    35701 tattcgcatc tctcatgccc tccgctacaa caagcggtcc tgacaccttt acaattgtgc
    35761 ctgttttcat attctctcac ctgcaatcat atactttatc aaaatttaaa tattccctcc
    35821 tatattttat tagcacatat atttagcacc aataaaattt gagattgtct tttattcaac
    35881 tttcatctat tctttaaata atatatctgc acctatagca cgtttactag attctcttac
    35941 ttcattcata cctaatccca tacttcctcc aatacctgga ataactataa tggcaggaag
    36001 ttggtaatct ttgtattttg ctattgattc ttttgcaagc aatgatgcct gttctgtaat
    36061 ataaattatc gcatattcat cttcaaccaa cttatgtata ctttttttaa tttcgtcact
    36121 atcataggct gggaagatat ctattccaag agctaaaaat cccatgatgc tatctttatc
    36181 tccaactact cctaccttat acataagcat cccttagcct ttcttttata gtatctgcgt
    36241 ctatattatt aagcttacta gtcaaaataa ttctaattgt ttttatctct gattctttag
    36301 catataaata tgcaattagt ggttctaatg taagaggctt aaattttgct cctctaacat
    36361 attccataag atagtcatca caaagttttt caaagacagt aaaaccacta tccatgccat
    36421 ttttacagac atcagagtaa gaagtagatt taaaacatga tgctggagta tctgaggaaa
    36481 aagcttctaa gaatttttcc ttatcaagtg agccacctga aacaaacaca ttcataaaca
    36541 tatcaaaatc tttcttcata tttttgactc ttataaaact ctttagattt gttaaatcac
    36601 aaactttcat aacataatct attacaaatt tgttttggct ttctttagca gtttctttca
    36661 tactggtaaa ggttgcttta tctagaacaa tatcaaccat ctggccattt tgtgtcttat
    36721 tataaacatc aaatgcctct aatatagctg atgacattat cttaggtaaa tcactaaaac
    36781 tacgatttgc taaagattct ctaagcttaa taagaggaat tgtacctcca tcaattaaat
    36841 atttctcacc atctacacca gaaatttctt ctttaatcag cacttttaaa ttgtgatagt
    36901 catttttata aagaaataca tcaacaaatt tttcttcagg agctagactt ttaagaattt
    36961 catatgtctt tgataattct tgagtcaaaa tattctcaaa attatgtata ttattatttg
    37021 atgtatcagc ataacctgcc tcagctataa ttcttaaaga gtcttcaggg cttttggctt
    37081 ctgccatttg aataaacatt tgtctgttaa gaagctgttt ttcaagcact cttattcgtg
    37141 caacggcata gggataagtt ttttcttctg ccatttttta acccctcctt aattaaacaa
    37201 aatttctgct gcaatttgtt caatatattc atgctctact gcaattatgg cttcaaatga
    37261 ataattgtac tcaatgtcac cttttttaac tatgaaacct ccagtaatat ctctagtttc
    37321 atcagacact ttaatgcctt tttttgatag cacatctttt aatgtttttt tatctttttt
    37381 agataatact atctctgaat catctgtaca atttgatttt tcaatcatgt ttagtataat
    37441 ctcttcatat tcattatctt taagatttaa aagtttgttt ttagcttcta aaattacctc
    37501 ttctaaaatc tcttgttttt ttgataatat ttgcttttta gcctccatat aagctcctga
    37561 tatttcctta gaagccgctt tttctgcttc tgcctctgca agctttgtat aggaagccat
    37621 ttccttttca gctttttcat tagctgaatt tacttttaaa tctgcttcac ttttagcttt
    37681 atccaatatt tcttgtgctt cttgtttggc atcagctata attctgtcaa tcattttttg
    37741 ttcattaccc ataggagtgc ttcctccttt tcattttttt tacttatgaa ttataattta
    37801 taattaacca attgcaattc cattgtaagc taagaaagaa acaagtagtc ctaaaagagc
    37861 atatgtttca actattgctg caaatgttat agctttacca agttcttcag gtctttttgc
    37921 aactattcca actcctgctg ctgctgcttt accttgtgct atacctgata ctaaaccaac
    37981 taaaccaatt ggaagtcctg ccataagaag ttgtaaacct tgagctgatg ttggtattgc
    38041 atctccacca ataattcctg cttttgataa aataaggaaa gctatgataa atccatacag
    38101 accttgtgta ccaggaagaa gttgtaaaac tagaagttga ccgaatttac tagggtcttc
    38161 tgttacaaca cctgctgcgg cttgacctgc tattgaagta cctttagcag aacccatacc
    38221 tgcaaataat gctgctatag cagctcctga tattgccaaa aattgaccat ttcctaacgc
    38281 gtttaaaaat tccatattta catctccttt ttattaatgc ttgtatattt tgttttatac
    38341 ttaaacggaa caaaaggaac tcctccgcct tcataaaact tattgaaaaa ttctacatac
    38401 tgtaacctac ttgtatgaac atatgcacct agtgcattta taagaaggtt tattgtgtgt
    38461 cctacaacac caattacaac tgcaagtatc ggaccagcta tagctcctaa aaggttgata
    38521 acttgtgcta taactcctgt tgttaaacaa agcgccataa ttcttgtata agataatata
    38581 tcagcaaaat aacttgttat accatagaga cttgaaaatc ctttaaaaag cttaacagga
    38641 atacctttaa agcttcttcc ttgagtaagt acaagaccta tagcacctat aattgctaaa
    38701 tattttccta cttctgaaaa tacacctata tcccctgcaa caaaaggtat tataagtaga
    38761 catacacctg ttatacacaa ataccaaaaa cctatgtcaa agattgcatc tattaccttt
    38821 ccacttctta ttaatgtata tgcttttatt cccaaaccta catatatatg gataataccg
    38881 aacagtaacg acattcccat aagtgtcata acatcctcta aaggattaat taatgctttt
    38941 ataggaatta aatcccccaa aatacccccg aatataagac cccatacagt agttgaaact
    39001 ccacagatac caataagttt aattaaattt ccttcacctt tttgtatctt taatttatat
    39061 acaacaaatc cacagactac tgcaattatt aacccatatg cggcgtcact tagcatcatt
    39121 ccaaagaata caacaaagaa gaaagttaaa attgtatttg ggtcaatatc ttttgtactt
    39181 ggatagctgt acatgttagt tacactttca aaaggtgtta ctaatttatt gttttcaagc
    39241 agaattggga agccttcttc tttacttcct tcttcagtct gaacacaaca attaaacttt
    39301 tctgtaattt ctttaattaa ttcatctgcc cttttgcttg gtaaccaacc attaagacag
    39361 aatgttgttt ttgttttgac aagtctctct ataatctttt tttggtctct ttctatagtg
    39421 taaaaatcat ataggttttc aagcatgtgt atactatctg catgtctttt aatttcctct
    39481 gttttgtcct tagaaacgtt ttcctgtcta attatcattt cattgtattt cttgatagct
    39541 tgtaacggtg taccttcttc atttggtaat gaaaccactg aaaaattaaa ttcttttaaa
    39601 acttctaaaa catcatcaaa agtttctttt aaagtaatta aataaacata gttcattaac
    39661 ttgtcagaat tgacaatccc aataacactt tctggtattt catcttctaa ttttactctt
    39721 aaagcatcaa tgtttgcgct tatgggcaca gttccaagta tagtttttgt atacttagtt
    39781 tccatatttt caagaggaat atcaaagttc acccatggtt ctaacatact tttattgttg
    39841 ttaagtaagt ttatgttaga ccttattgta cctatctcct tgtgcaaatt gtttaactcc
    39901 agagcttcag cataaacttg cccttctttt tcactatcaa ttttgttaaa ctctcttttt
    39961 ggtgcaagta gggatttttt ttgtttcact agtgaagaaa caatattaat tgcttggttt
    40021 acatgagaca ttttctgctc tagcattata acttcagatt cttcactatc ttttacaaga
    40081 taatttttta attcctcctc ctcagtaaga aaggcactat catcaatctg aacaaaccca
    40141 cggttcataa gtagctttaa aatctggctt ttttgagctt ctaagccaac aatagatatt
    40201 ttgttcatat taactattgc catattatct cactaccttt ccaataaccg cttcaatagc
    40261 cttacttttt ctttcttcag cagttttttc aattttcaga cattcacttt tagcattagc
    40321 taagatttta tcaacctctg ctctactgtc ggtgactgcc ttctcaataa gagtttcttc
    40381 cataagcttt gcttgttttt ttacatcagc aaatatgctt tcacatttgt ttacagcatc
    40441 agctctgata gactctgcat cagtaacagc ttttactttg atactgtctg ctgtctgctc
    40501 tgcctcaaca atgcttttta ttatttcaaa agccatccaa atcacctctc ttaccttttt
    40561 actatgtata taaccaatta gattttttta ttctaattag attactacct cattgttaaa
    40621 gtataaacag catttttata taataattaa tatttttcaa cgtttatttc ttaataaaac
    40681 atattttaga atagtacttg cctagattta catccttttt tgacttactt ttagactatg
    40741 acatgagtat ggtttttaaa taccattatt ttcaataatt ataatttaaa gcgatatagt
    40801 ttgtcaatag cgttattttg ttttaaaatt aacgttatgt cgacatttta aatttttatt
    40861 ttattttttt tataatttta atttaattta ttacatataa aagtttttta tattcttttt
    40921 caacctctaa ccattgaagt ttattgtttt ttttgaattt ttagaaatat ctcgcactat
    40981 tttatctaac ttttataaat catcaagcta tatcgatttt tgtcacctta tttttaatct
    41041 aattttttta tatctagtta gaaataaatc aatattttta aagattgata aaacttacac
    41101 ctagttctaa tagttttatt ttaaggcaat gtattaatct taagtagata atatcattag
    41161 ttactctata tattcgacaa cattataaaa aaatcctcgt accaatcact ccaatcttca
    41221 ataggatatg ctgctcctcc atttacactt ttcagtagat tggatgtata ttcttctccc
    41281 atagaaaaaa gttcccctac tgtcatatca taacctctag atgtaacaac cttacaaaat
    41341 gaatccataa catcacgttg ttctcttgtt tttataagtt cttttctaaa ttcatcatca
    41401 ttcttagctt cttctaaaat tttagttaat ttttcattca ttatgtattt ctccttttaa
    41461 gtagtctttc tgtaaacttc aataagcttt atataaaaag gaagccatcc taaataaact
    41521 aagatgactt cgcttaactg ttagcaacac atttactagt ataaaataat tggtgtacct
    41581 ggttctatat tttcatatat tttctttgcc ttagaaaaag gtgtatttac acatccatgt
    41641 gaacctgaag acttatatat acttccacca aaagaatttc tccaagtagc atcatgaatg
    41701 cctatgttcc cattaaacgg aagccaataa cttacaggtg aactgtaacc ttgaccagtt
    41761 aatgaaacat ttctagcctt ataattaaga ggatatatac ctgatggtgt agcaaatcct
    41821 ctagctaaat cacctgttac aacgtctgtt gatacaagca tttctccatt tttaaagaac
    41881 cacatatgtt ggccagaaag actaatctct acatatgtat ttccaatatc atctttatta
    41941 cgagatacag ctttttgtat gtaaataggt tctcttgtaa catttttacc agcttttaca
    42001 acatcaacta atgcttcagc ttctttcttt ttatctatca accaaccata aattccacct
    42061 gaaattgtaa tatctttacc tgtggcagtt ttaaatggtc ttgagtcacc aaaagtactg
    42121 tattttttac ttaaacctct tgtatattct accatagcat cattatcaaa agttatgtca
    42181 taattctttt ctgagtctac ttttaaccat ttattaattt cagaaccatc taaagtttcc
    42241 ttacggtcac taaaatcata tgtaacgact acaccaacat acttatctaa tgtcttaata
    42301 gcttgtttca acttttctga atcctttgtg ttgtttggtg cttcataaac tttactttca
    42361 tccagagaaa tagaagtatt cccagaatta attgagtttt gtactaactt ataaaaatca
    42421 tcttttttca ctttgtttcc aagtacctct ggtactataa cataagcgtt tttagtgcta
    42481 tcatacttag gataagcact cttaggttct acaacatttt tactatcaaa acaagataaa
    42541 gcattaaacc ttttttctag taaatcttta ttatatgaaa gagttatcat attattatac
    42601 tctttagact taaatattcc accaatccat ccaatagcgc tctgactatc ttttatcttt
    42661 tgaactttat catctggtgt aaattttaaa tcaatatctt ttgcttttat ttgttctttc
    42721 ttattgtttc tttcctctaa gtttaaagta taggaattag tactagatgt taacaaatca
    42781 tttacttgct caactgtttt tcctgaagcc tttacgccat taatagtcgt tccaaagtaa
    42841 aaatgatttc taaaaaagat tgccattcct atataagcta caaacaaaac acctactact
    42901 atagctatct taaattttag atttttttgt ccactttctt gttttacctc ttttccatca
    42961 atcataatta aatccttcct tacattgtaa ttacctatgt accttattgg tttttaaaca
    43021 aaaccatgta tgccttattt tatataccca aattactgta tcattattta tatttttaaa
    43081 tatatagtta tttctataaa accattttat cttttagata aaatgattat tataaatccc
    43141 ccctttcaaa atcccttaaa cacaatctct gctatattaa tatattacca tacttttaat
    43201 aatcgtggga ctatctatct atttttgtaa cactaaacta ctattttaaa aaagaaacta
    43261 attttgtgtt agtttcttta tcttaactta tttttatatt gaattttagc ttaacataac
    43321 gttgttatat agattctatt taattatttt agtttctata tcttttccat ctgcatattc
    43381 tttaagtaat tccttagcat atccaaaata ttcttcaata tcagattctt gactaaaaga
    43441 aaatatacaa attaatattt catttgcatc ttctgttatc attgctcttt cagaatcact
    43501 agttggactc ccaaatttac ccactgaatc agataatata ggaagatttt ctatatttat
    43561 taattctttc ccaataccct tatactgttc tccttcatct cctacagtaa aacatactgg
    43621 tgaatgtaat ttgcttacat tatatgtacc tactggatat aatgatttta ttgatattaa
    43681 attgtttatt tctactatat tatttattgt ataaagaccc ttcccttgaa taattcttct
    43741 aaccaatgct tctgaagatg ttctatatct acttggattt tttccaagct ctttataagc
    43801 atttcttgca tctttaattt tatctagttt cgtaatgtct tcaactttta gactttgatt
    43861 tatagtatca caaaactcat ttatttcatt aattaatttt tctgagcttt tatttactgc
    43921 tacttttgct tgaatgcaac ccagcttagc attaggccat ctttccttaa gtttgtcatc
    43981 aatacttata tctatcatac ttaaacaact cctatacact aaatttttat taaagttttt
    44041 atcatctata cattatagta ctattctttt gttaataaca tgtttattag caaaataaat
    44101 ttatttttaa tataattttt ataaaataca attatttttt gctttatatt agacaataca
    44161 ttgataaaat aaaaaaacac taattattta gcaatgattt attaaaatca agcattcata
    44221 atagtgcttt atataaaaat caaattttgt tttaaagtaa atctaaaaaa ttcttagctg
    44281 gcattggtcg tgcaaaataa aatccttgaa ctaaatcaca tccaaattgt ttcattaact
    44341 cagcttgttc tttactctca acaccttcta taattacaac taaatctagt gattttgcta
    44401 gagacactat tgattttgct atattgcgac ttctctcatc atgttcaatg ccaccaagaa
    44461 aagacttatc tagcttcaat atatcaattg gcatatctct taaacaacta atagaagaat
    44521 atcctgtacc aaagtcatcc atagaaatag aaaatccata cgtcctcaac tcatttaaaa
    44581 cattctttaa aatatttaac tcattaatag ccacagtttc tgttatctct atttcaatga
    44641 aatctgaact taaattatac atttttattg ttttattgat aaattttaca atatctggtt
    44701 gatacaactc gaccctagat aaatttactg aaactggaac tatcttttta ccttgctttt
    44761 tccattcata taaatcattg caaacccttt caaatacaaa tctcccaatt tttaaaatca
    44821 acttactttt ctctgctatt ggaataaata ctgcgggact tataaaacca tgttctggat
    44881 gattccatct tattagtgct tcactcccta tcatttctcc agttacaagt gaaaacttag
    44941 gttgataata cacttcaaat tgatttttta ccaatgctat ttttatatca tctaaaatca
    45001 ttgattcctc actaagctta ttcctaacat cttcattata aatagcataa tttatatttt
    45061 tacctttagc aacagaccta gccatatttg ctttatttac agccttttga atatctactt
    45121 caccttcttc aacaaaataa atacccacac acagagaaat ttcaaagact atactcaaat
    45181 tactttcaat attacttcgt atattatcaa gttttcttat aattttattt cttccatttt
    45241 tataatcaca gaaaattgca aaataatcac ttgaaagtcg tgcatatacc tcaccttctg
    45301 ttaattcttc ttttaaagct tttgctattg taattaataa attgtcacca aattcatatc
    45361 caaaagtatc attaatcatc ttaaagttat taatatcaaa atatactata atataattta
    45421 aagatggttt atctaaaaga tacttactac attctctata aaatttattt tgatttccta
    45481 tatatgtaac tttatcttca taagccaaac ttaatatttc tttttcatta gattttttta
    45541 tataaattat ataaaaaata attgcaataa atattaatac aatagataac actgcatata
    45601 cagctctgtt gattatttgt tttgaattac taaatacaac agtttctgga attgaaaaaa
    45661 ttaaattcca gtcttttata taattatttt cactattccc attatccata gtggcatatc
    45721 ctaaatatct tctttcttcc aacatattta atacagttgc acctgtttta ttttcttgca
    45781 attctttttt taatctattt acttcttgaa tatcattatc ctgttttaac aatttataaa
    45841 tattttttga taggctatcc ccttgtggat gaaggataat tgtaccatta ttttttacaa
    45901 cataagatat actattattt tcataaaaag atatattaat aagtttcatc agagtattga
    45961 tattgtaagt acaatataaa actccaacta ctttatcatt atttaataat ggtactgaaa
    46021 tagcaatctt ctttatagac ttatttactt catcaacata tggacttgaa acatacttct
    46081 tacctttaat tgagtttttg aaaaattctc tatctttcac tgaaaactta tcacctttgg
    46141 tattttcagc attaccattt atatcaacta ttgccatagt gtaaaatttt tgattttcca
    46201 tttcatctaa aagatttttc attttttcct cattaggtat atctggattt gaagcataat
    46261 agttagaaaa aatatttaaa acatctaaat ctttttcaat ttgtctttgt gctagttgag
    46321 agccttgtac tgcaacttct tttatatgta tttttgcctc tgacataaga agatgttttg
    46381 tatcttctat atagatatac cccattgtca aaaataatga tgttaaaaaa agaattgtaa
    46441 ttaatgtaaa acttttattt ctccctgtca ttcgactcct cccctaatta gtcaatactt
    46501 catatagata atatatcctt tttataccaa ttcatcattt atattgtata taactattct
    46561 taaatgttac acataaaatc aacataataa ccataaaaac attcttttat tattataata
    46621 acactattta attgaatttt aaattaaaga ataaaaacta tccattttct caaacaaaaa
    46681 aactcttata caataaaact ttgttttatg tataagagtt tttattttat ctattttata
    46741 gcaaacttat cttccataat atgaatttaa atacatatct tttatttcat tcataagtgg
    46801 atatcttgga tttgctcctg tacattggtc atcaaatgct tgaattacca tttcatctat
    46861 tgaatccata aacttagatt cttcaacgcc aaactctttt atagatttag gaataccaac
    46921 tttaagtttt aaatcttcaa tagctaccaa taaactttgg aatttctctt catcagaatt
    46981 tccttttaat cctaaaaatg aagctatttc agcatatctc tttaatgctt ctggatattt
    47041 atattgagag aatgctccca ttttctttgg tgcatctgaa gaattaaatt tcataacttc
    47101 tgttatcaaa agagcatttg caacaccatg tggtacatgg tggaaagcac ctaatttatg
    47161 agccatagag tgacaaacac ccaaaaatgc atttgcaaaa gccatacctg ccattgtaga
    47221 agcatttgcc attttttctc tagcttctgg gtcttttgca ccattatcat atgcacgtgg
    47281 aagatattca aatatactct taatagcttg taaagctaat ccatttgtat aatcggttgc
    47341 aagcatagat acatatgctt ctaatgcatg agttaaagca tctataccag aagcagatgt
    47401 taagcttttt ggcatattca tcatcatatc agaatcaact atagccatat ttggcatcag
    47461 ttcataatct gctaatggat attttactcc tgtatcttgg tcagttataa cagcaaatgg
    47521 tgttacttct gaaccagtac ctgctgatgt tggtatagct acaaaattag ctttttcacc
    47581 cattttaggg aatgtatata ccctttttct tatatccata aatctcatag ctaggtcttg
    47641 gaaatctaca tctggatgct catacaatgt ccacattatc tttcctgcat ccattgcact
    47701 tcctccacct atagatatta ttacatctgg attaaattct ctcatagctt tagcgcctat
    47761 cttagcacat tccaaagttg ggtctggttc tacttcaaag aatgtagtgt acttaatatt
    47821 catttcatct aataaatcag taactgcttt agtatatcca ttattgtaaa ggaatgtatc
    47881 tgttacaata aaagctctct tcttattcat tacatcttta agttctttta atgctactcc
    47941 taaacaacct tttttgaaat aaactttttc tggtgctcta aaccaaagca tattttctct
    48001 cctctcagct actgttttaa tattaagtaa atgcttaact cctacatttt cagatactga
    48061 atttccaccc caagacccac atcctaaagt aagagaagga gctagtttaa aattatataa
    48121 gtcccctata ccaccttgag aagaaggagt attaattaaa attctacaag ttttcatggc
    48181 tgaagtaaac ttatcaagtt tttctctttg atttacatca tcaatatata atgaagatgt
    48241 atgcccaaat ccaccatctt ctactaattt ttctgctttt ctaactgcat catcaaaatc
    48301 acttgccttg tacattgcaa gtactggtga aagtttctca tgagcaaaag cttcttctat
    48361 ttcaactgat tctacttcac ctattaaaac cttagtatct actgggactt caaagcctgc
    48421 aagttttgct atagtacaag ctgtttgccc aactatttta gaatttaatc ctccatttac
    48481 taaaattata tttcttattt tttctgtttc atctttatct aataaataag caccacgctc
    48541 tttaaattct tttttgactt cattgtatat attttctaat actataaccg attgttcaga
    48601 agcacatatc ataccattgt caaaagtctt agatacaaga attgagttta cagcagtttt
    48661 tatatctgca ctatcatcaa ttattgctgg agtattacct gcaccaactc caatagctgg
    48721 ttttccagat gaatatgctg atttaaccat tccaggacct cctgtagcaa gggtcaaatc
    48781 cacttctttc ataacagttg tagttaattc taaagatggc tcatctatcc atcctattat
    48841 accttcagga gctccagcta aaacagcagc ctcaagaaca acttttgcag cctctatagt
    48901 agaatttttt gctcttggat gtggagagaa aattattcca tttctagttt ttaaagctaa
    48961 aagtgcttta aagatagcag tagaagttgg attagttgta ggtacaactg ctgcaataac
    49021 acctattggt tcagcaattt tagtcatacc aaatgcttcg tctttctcta taacaccaca
    49081 agttttagtt tctttatatg cattatatat atactctgag gcataatgat tctttataac
    49141 cttatcttca gcaattccca taccagtttc tttttgtgcc attatagcta gaggaactct
    49201 ttgcttatta gctgccaaag atgctgctaa aaaaatttta tctacctgct cttgactata
    49261 tgtagcaaat attttttgag cttctctgat ttttgctagt tttttaacta agctttcaac
    49321 gttatttaca gtatctaaac caactgacat aacttcattt tcttttttat tttctattat
    49381 tacttgttct ttatgagcca ttttaacaac ctcctgagat agttttttat ttattatgtt
    49441 aatttattaa cattatagca tttacttttc ctattttcaa gttatttttt taacatttta
    49501 ttttttatct aatataacat catttctact aataatatct agctttacaa atacttaatt
    49561 taactagata tcactttatt ttttacgcaa atcactaatg aaatcatcta aaaacttaag
    49621 gataacgtta tttttttaac gtttatattt ttgtattttt tgcaaataaa actttataaa
    49681 aagaattttt aatatgatac tctatcaagt ttaaaaataa aaatccttga aaatgaaaat
    49741 taaaacttaa ttaacaagtt aaagtaaata tagttaaatg tacaaacatt tacaacatat
    49801 agtataa
//
LOCUS       DAYAOO010000023        49678 bp    DNA     linear   BCT 12-OCT-2024
DEFINITION  TPA_asm: Clostridioides difficile isolate ST8-SSI-h139-18
            SAMN40601845-rid21577343.denovo.023, whole genome shotgun sequence.
ACCESSION   DAYAOO010000023 DAYAOO010000000
VERSION     DAYAOO010000023.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN40601845
            Sequence Read Archive: SRR28438827
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 49678)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 49678)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-MAY-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-MAY-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002157583.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002157583.1
            Genome Coverage       :: 163x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/11/2024 16:19:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 4,038
            CDSs (total)                      :: 3,963
            Genes (coding)                    :: 3,930
            CDSs (with protein)               :: 3,930
            Genes (RNA)                       :: 75
            rRNAs                             :: 6, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 60
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 33
            CDSs (without protein)            :: 33
            Pseudo Genes (ambiguous residues) :: 0 of 33
            Pseudo Genes (frameshifted)       :: 7 of 33
            Pseudo Genes (incomplete)         :: 25 of 33
            Pseudo Genes (internal stop)      :: 11 of 33
            Pseudo Genes (multiple problems)  :: 8 of 33
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..49678
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN40601845-rid21577343.denovo.023"
                     /isolate="ST8-SSI-h139-18"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Denmark"
                     /collection_date="2018"
                     /collected_by="Statens Serum Institute"
     gene            109..783
                     /locus_tag="ACGI5H_001435"
     CDS             109..783
                     /locus_tag="ACGI5H_001435"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417819.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000156 - phosphorelay response regulator
                     activity [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HFG9697146.1"
                     /translation="MNNKILVVDDEEGIITLLKDYFEMNGYEVYTAQSGKDALKKISK
                     NPDIILLDINMPEIDGIEVCNRIRDYVSCPILFLTARIENTDKINGFRAGADDYIVKP
                     FDLDELGARVSAHLRREQRKSNQTKIKFYNDLTIDYEKRLICIYNNQISLSKKEFDIV
                     ELLSMNPGQVFDKEKIYDRVWGYNSNGNSDVIMEHIRKIRIKLSKHTLENYIETVWGV
                     GYKWIK"
     gene            771..1931
                     /locus_tag="ACGI5H_001436"
     CDS             771..1931
                     /locus_tag="ACGI5H_001436"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728740.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HFG9697147.1"
                     /translation="MDKINNMSLKKAFFVLTLSSLIIASVLTTFAYILLNNLYNSIQD
                     KYLKTPINTGIITIVQNNVNQFSDYDKTLLNIINILQLVLPLIFFIGLLLLADIIFYK
                     VKLKTPIEILNKGAMEISNNNLDFCLEYNNNDELGNLCNAFEKMRSELNKNNIKMWTM
                     INDRKQLNAAFSHDLRNPLTVLKGYSNYLTKYIPTGKLSDEKILSTTQLMSEHINRIE
                     YYVENMSNAQRLEDLVVSKSMSNINKFIENLDENISIIAKQEGKSFTLKSQINNINLF
                     FDENIILRVVENIISNAFRYARNNVSILIYLEQELLTFVIEDDGIGFSKESLKLALRP
                     FYRDKTLNDSNAHFGMGLYISKILCEKHGGSISIENNSTNSAKITAKFSTRN"
     gene            2168..2674
                     /locus_tag="ACGI5H_001437"
     CDS             2168..2674
                     /locus_tag="ACGI5H_001437"
                     /EC_number="2.7.8.-"
                     /inference="COORDINATES: protein motif:HMM:NF013250.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_function: GO:0000287 - magnesium ion binding [Evidence
                     IEA];
                     GO_function: GO:0016780 - phosphotransferase activity, for
                     other substituted phosphate groups [Evidence IEA];
                     GO_process: GO:0008654 - phospholipid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="CDP-alcohol phosphatidyltransferase family
                     protein"
                     /protein_id="HFG9697148.1"
                     /translation="MTFSRIVFALLMLSSTFSSLPFWICYFWCGISDILDGLIARKLR
                     QQSGIGAKLDSIADFIFAVTILVTVGKNIALPMYLWWCIVAIALLRLISYSIGFFKYR
                     TFSSLHTLMNKITGISIFAFPLLYICFGLDVAGIMICIVAFLSSFEEIAIMIKSKELN
                     RDIKSIFM"
     gene            2960..3628
                     /locus_tag="ACGI5H_001438"
     CDS             2960..3628
                     /locus_tag="ACGI5H_001438"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895525.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HFG9697149.1"
                     /translation="MIIKAKQLSKIYGSNNNKVIALNNVNLEINSGEFVSVIGPSGSG
                     KSTLLHILSGLDNPTSGQVLLDDKDIYKHTEKELSALRRKSFGFVFQQFNLLPVLTAS
                     ENISMPVLLDKKQPDKDYLNEISSLLGIADRLNHLPHELSGGQQQRVAIARALIAKPD
                     IIFADEPTGNLDSKSGSEVMNLLIKTSKQFGKTLVVITHDDRIAKLADRKISIIDGVL
                     MEVK"
     gene            3631..6099
                     /locus_tag="ACGI5H_001439"
     CDS             3631..6099
                     /locus_tag="ACGI5H_001439"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860832.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HFG9697150.1"
                     /translation="MKNYLSLSIKELKSQKFMTTFIIIAIVLSTIMTTVVGQSIGILQ
                     NLRIEQARSFNGDRHVSFHQLTKNQVDDIKKDDRVYQAGTSITIGSSKIKDSGISVLV
                     KEYDKTGLSNYPKLMKLKSGHLPKDKNEIALDENTLKLMGIKPRLGVTIPMNLDISLL
                     NDTIPPYNYTANFKLSGILEDDYTGYVSGIVNGIVGKGTSENLLPKRYILSSLDFKIK
                     QQEKFQEIVNQLAKKINLSHNSIQYNWIYLNALKIQFEKDENSSNSDGISMIILVSLF
                     VALLVLLASGLVIYNILKISVTKKIKEYGCLRAIGAEPNQIYKIVILQILILCTVAIP
                     IGAVIGIISSKGITGMVTNILNPDILLANDNKEITELIHKNTTAYIFPLVLSTNVSLI
                     FSFISALPSAIYASHVSPKIAMVGSTTKIKRKIKREKTIKNFERHLAWLNLKRNKGRT
                     IITILSLFMSITVFVALSEFSNVLDVSRSVSNLKEGDFSLTNEISGFDKSTLDKIAKM
                     KNVNRTSFIKYSEYKQGEIDTDINFENSGEMLKIIGIDEQTLKDLMPSITDSILEDFK
                     NGSICFIKNPIAISTPGVKTRYTNLKPKDSITINKKQLDIYSTVDKMFFLQGNGWING
                     VDVIVYDSVYNTLTNKNKFNQINIYAKDKSKLEQIRLSIEQICENNPGSHWISYIESD
                     KQLKESFKQIEFLAWAVILFVGLIGTLNIINTTHTNINTRTNEIGVKRAIGMSNRSLY
                     KMFLWEGVYYGIFAAIFGSIAGYASAIIINMATIEKLDFTNIPITSILQATIISVLAC
                     IIATLIPLRKVKKMNIIDCIDINL"
     gene            complement(6339..7763)
                     /locus_tag="ACGI5H_001440"
     CDS             complement(6339..7763)
                     /locus_tag="ACGI5H_001440"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895522.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HFG9697151.1"
                     /translation="MKNQSLITQFRHTFIFIIIASIVATVITYVFALYLYIHSLNKDI
                     YPPNYYERQVPRIEKYINEKNIALLSQSNEEGLKRTIRGDDMLYQVVDNNGNILYGTN
                     PKKLFKTKEELFNNFINKTVRKGGYIHTVPIKGDNGKIEGAVILFYQVKITFANIRGR
                     FVFAVIIMALFSPFLYIVGFTRWLSKRFVKNINQPLHLLIDASKKIKEKDLDFEIDYY
                     SDNELGKLCSAFSEMKDELKGSLSAQWKMEQERVEMVEALAHDLKSPLSIILGYTDAL
                     IGNNTDDNEKLHRYLTVIRENTEKSAALVQKMQYTSDLEKSNIQLNLVPINLPEFLRQ
                     KVQDYELQAHQKEVELILKMQGNIQSPIQIDVDRLTRIFDNIISNSLQYTPSGGNISI
                     TVKDEKNCISYEICDSGRGFSSKDLKKALDKFYRGDEARQTKGGHSGLGLYIVKQLVE
                     QLGGSVKIENSKSGGACVKFWHSI"
     gene            complement(7782..8474)
                     /locus_tag="ACGI5H_001441"
     CDS             complement(7782..8474)
                     /locus_tag="ACGI5H_001441"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417590.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000156 - phosphorelay response regulator
                     activity [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HFG9697152.1"
                     /translation="MSKILIIDDEMDLVMLLEDELKAKGHEVLIAYDGQAGIELSKQE
                     PDLIILDIMMPKMNGFEVCQAIRDDVLCPIIFLSAKQSETDKIKGLTFGGDDYVTKPF
                     GLRELMARIEANLRREKRSQYINEENKRSTLYFGKLCLYMKERAIKIDGKNIDLTKIE
                     YDIVELLALHAGQVFSREQIYEKVWGCDSEGDSSTVVERVKKIRAKFSAVTPEKEYIS
                     TVWGIGYKWNKM"
     gene            complement(8526..9305)
                     /locus_tag="ACGI5H_001442"
     CDS             complement(8526..9305)
                     /locus_tag="ACGI5H_001442"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009901952.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lantibiotic immunity ABC transporter MutG family
                     permease subunit"
                     /protein_id="HFG9697153.1"
                     /translation="MIKLLSSEWLRAKRTAVQWLTLCMPIIFSLCVVFYLTTKSGSTQ
                     EFAFEGFFTVWTVFIIPIGVGILAGFIVQEEELAGNFNGFLCVGISRVRLYLGKFLFL
                     LFCLTICTFIATLILCIGMSIAVPSGATIWLFLSAAGLVVIGTLPLLAIHLWVSFAWG
                     MGASIGISIGGILMAAILGLTSVGEKVWAFVPWTWPVKLGMLPGIYFIKEAGTISTEA
                     FYSKVMQTASIELIVVAIGLIIFLIGGVIWFKMWEGRKSYE"
     gene            complement(9302..10072)
                     /locus_tag="ACGI5H_001443"
     CDS             complement(9302..10072)
                     /locus_tag="ACGI5H_001443"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888312.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lantibiotic immunity ABC transporter MutE/EpiE
                     family permease subunit"
                     /protein_id="HFG9697154.1"
                     /translation="MNALQSELLKYKRTFMGKLIVFFPVSFAAYAFIMQSTLMQNPLS
                     QTTSWAWQNLLALIFNWWSFLFLPIGFALFATLVAFQEKKAGNYRALRTHNVSPMTLW
                     INKVIAMAVYSFISTLVLIVVTIITGLILKAGPVPFGQIIGASIVCWVVSLAILPLQL
                     WLATWKGMFLSMGVGALGMIFGVLAATKPFWIAVPWSWAVRMVCPIINIHPNGTILEA
                     GDPLLNTSVIPIGIVVSLVVFIVLTALTAAWFNRRDDK"
     gene            complement(10069..10773)
                     /locus_tag="ACGI5H_001444"
     CDS             complement(10069..10773)
                     /locus_tag="ACGI5H_001444"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014466355.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lantibiotic protection ABC transporter
                     ATP-binding protein"
                     /protein_id="HFG9697155.1"
                     /translation="MKDLILETKNLSKRYGEQMAVNNVSLQIERNSIYGLLGPNGAGK
                     STTLKMLVGLLRPTNGRIIFDRKPWKRESLAKIGSLIESPALYGNLTAEENLLVHTKI
                     LGIPKDKIYEVLEIVNLKNTGKKRASQFSMGMKQRLGIAIALLSDPELLILDEPTNGL
                     DPFGIQELRELIASFPKKGITVILSSHILSEVAQVVDNIGIINGGRLLFQGMPDPNEN
                     LEEFFTDVILKGGQNR"
     gene            complement(11028..11540)
                     /locus_tag="ACGI5H_001445"
     CDS             complement(11028..11540)
                     /locus_tag="ACGI5H_001445"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860830.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9697156.1"
                     /translation="MKKISQEKISTHIQEIPQEKIEQWKSLYEKYKSILKVNSKSVLE
                     IIEFLKRKYVIVEETSEEFKHVVINNIKLNKPFSQKISSDKELKPIVFTIPNEGNAKK
                     LYDTQEEIYSDCKIIVGMEFETGCVFVEGSDELNDEITSFKGLDKYDINNYYLVANYI
                     RCLKKYKLID"
     gene            11866..12123
                     /locus_tag="ACGI5H_001446"
     CDS             11866..12123
                     /locus_tag="ACGI5H_001446"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426325.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9697157.1"
                     /translation="MILNRAELFRGYSLNRFNEICNILSVNKIKYKYKVKNNAYSKKP
                     FFNEITLGNLGQKEDFSYEYLIYVHKDDYEQAESLINSKLR"
     gene            12266..12892
                     /locus_tag="ACGI5H_001447"
     CDS             12266..12892
                     /locus_tag="ACGI5H_001447"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426324.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uracil-DNA glycosylase family protein"
                     /protein_id="HFG9697158.1"
                     /translation="MKINIKSKLSEFIKQNNLFDDSRIISYLPNITIETDKIKTIMIN
                     EVVPTNTNDDFYSVDKDADYLKTTIPLFDSAGIKVSNINDILDMGIYITNAVKLPKSE
                     YTITRDTIKLHMPILEEEIKLFKNLEVVMLMGDVAKKSFNMITKKHIKKNVIPSISTY
                     KLRNNELYYDNLRVFPSYIMTGGNILIEKSKFEMASEDIKKMFEIING"
     gene            complement(13139..13918)
                     /locus_tag="ACGI5H_001448"
     CDS             complement(13139..13918)
                     /locus_tag="ACGI5H_001448"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009901940.1"
                     /note="N-terminal region resembles flavodoxins. C-terminal
                     ferrodoxin region binds two 4Fe-4S clusters; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EFR1 family ferrodoxin"
                     /protein_id="HFG9697159.1"
                     /translation="MNSKIYYFSGTGNSLVVSNILKETLNGSKEVIPLAIHRKENNID
                     INEDILVIVFPVYFADVPDIVKSFVEKLNFNINTHIYAIATCNGVAGHSLFTIDKLLK
                     KRGKKLSAGFLINMPGNALITPPDVEEERLKNQTNRVAEIAKCINNLEIGNIEGKNNL
                     KSHIDSVVLRLVGKNMQIATTKFFAENKCNGCGTCKRVCPVENISIVDKKPKWGNECE
                     RCLACFHWCPKEAINVKKSFLTNRKKYHHPDITVKDIFLDK"
     gene            complement(13986..14447)
                     /locus_tag="ACGI5H_001449"
     CDS             complement(13986..14447)
                     /locus_tag="ACGI5H_001449"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888305.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family winged helix-turn-helix
                     transcriptional regulator"
                     /protein_id="HFG9697160.1"
                     /translation="MGGARDYLNGGKMKDFEKLYEATTKLVSTSLKVKDDLKKMFKQN
                     GYDITTDHYALLRFLWEQDGISQIDLCEKSCKDKSNTTRILDVMKNKGLIVRKVDVKD
                     RRKFQIFLTDLGRELEEPLNEIASIYATETFKSISDEELPLFTDILDRIGK"
     gene            complement(14423..15100)
                     /locus_tag="ACGI5H_001450"
     CDS             complement(14423..15100)
                     /locus_tag="ACGI5H_001450"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895507.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0009055 - electron transfer activity
                     [Evidence IEA];
                     GO_function: GO:0010181 - FMN binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="flavodoxin family protein"
                     /protein_id="HFG9697161.1"
                     /translation="MIITVINGSPRKNGATSKVLTYLYKDIERLIPDVKINYFDLSEV
                     NPSYCIGCLNCYKMGKCINQNDKVEYIHDIITKSDGVIFGSPTYGSSVTGLFKVFTDR
                     AHMMLERLLYRKPCIAVTTYENARGSKAISFIKSMVLDSGGYVCGSLSIKTGFNQNPI
                     TEKVESKIQKVSKKFIYCIEEKKNPPVLSQIYNFIAINAVLKPMAFKDIEQYKGIIDR
                     WEEQGII"
     gene            15333..15719
                     /locus_tag="ACGI5H_001451"
     CDS             15333..15719
                     /locus_tag="ACGI5H_001451"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895504.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0045892 - negative regulation of
                     DNA-templated transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="BlaI/MecI/CopY family transcriptional regulator"
                     /protein_id="HFG9697162.1"
                     /translation="MKKLPHISEAEYQVMKIIWKYAPISTTEVIEKLVETSTWSPKTI
                     QTMLLRLVKKGALTYEKNSRVFVYTPLVKEEEYVATESSSFLNRFYNGTLNSMVLNFL
                     ENDKLSEDDIEELREILNKRTTKGDK"
     gene            15722..17521
                     /locus_tag="ACGI5H_001452"
     CDS             15722..17521
                     /locus_tag="ACGI5H_001452"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426313.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008658 - penicillin binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="BlaR1 family beta-lactam sensor/signal
                     transducer"
                     /protein_id="HFG9697163.1"
                     /translation="MYAPFFIRFLLSTLTLSILIAVILLAKKVFKKHISAKYQYNIGF
                     ILLIMLIIPFVPLKYINLGNVFNYLYTFNQLGSSTNRTSMIKNSPNSIINNSNALNDF
                     SVSLNQVNFDSLNILLLISWIIGILIMIAITIHCNIKIKNMKKSIQILRDEEIVFIFE
                     KCKKDIGINKDFILCKSPIINTPITFGYFKPHIILPDKSISKLSLKDIKYILLHELQH
                     FKNKDILINYIMCFLQILYWFNPLVWYAFKEMRIDREIACDISVLKKLDKDSHIEYGQ
                     TLINFVDNISRPSNLTLTSDIGGSKKQIKKRLLKIMDFHNESNTLKFKSILIFTLIAL
                     IVFGNIPKLSIMADINEKYRPTNEQTVYEDLSQYFKGFDGSFVMYDLKSKQYHIYNKE
                     KSKTRISPNSTYKIYSALLGLENGIITRNNSHIPWDGKHHSNSSWNEDQDLFSAMENS
                     VNWYFQTLDKKTGLKNIQTYLRQIGYGNYDVSGGISNFWLESSLKISPIEQVELLESF
                     YTNKFKFEDKNIETVKDSLLISKKDGVSLFGKTGTANINGKDVNGWFIGYVEKNENTY
                     FFATNIQSKDYSNGSSASKITLSILNDKKIYNP"
     gene            complement(17876..19750)
                     /locus_tag="ACGI5H_001453"
     CDS             complement(17876..19750)
                     /locus_tag="ACGI5H_001453"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888302.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glucose PTS transporter subunit IIA"
                     /protein_id="HFG9697164.1"
                     /translation="MNKYNKIANELIKIIGEDNIISITHCATRLRVMVKDREIINDKK
                     VEKVDEVKGVFFTSGQYQIILGTGIVNKVYAEVEKMGLKTLSKKEQDELVKNNETGFK
                     KVMRTLADIFVPIIPVIAATGLFLGLKGCLFNDNVLGLFGMSSANIPLYIQTLVSVLT
                     ETAFAFLPAIIVWSAFKVFGGTPVIGLVIGLMLVSPILPNAYSVADPSNEIEAIMAFG
                     FIPIVGCQGSVLTAIVTAFIGANLEKWFRKHMPNVLDLIFTPFFVMLITMLVILLGVG
                     PIMHTIELKMVDIISLLIDLPLGIGGFIIGFTYPLAVITGLHHTYVMIETSLLANTGF
                     NALITLCAMYGFANIGTCLAFMKKSKNNQVKQTAVGAMLSQLFGISEPVLFGIQLRYN
                     LKPLIIMCASSGLGAAILSILHIQSNSYGLAVLPSYLMYIYDGYNLITYLLASIFVVA
                     FCFIVTCLFGVPKEAINEDEDEELVFNENNENFVSPAKGKIVALENVPDETFSKKMLG
                     DGFAIDIIDGKIVSPISGKLETVVSSGHAFGIKGTNGEVLIHVGIDTVALNGDGFDIA
                     VKQGDMVKQGDVLVNVDLKRIHELGKSTLTMVLFPDGKKVNILDINKDVKIGQRICVE
                     "
     gene            complement(19755..21419)
                     /locus_tag="ACGI5H_001454"
     CDS             complement(19755..21419)
                     /locus_tag="ACGI5H_001454"
                     /EC_number="3.2.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426300.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004553 - hydrolase activity, hydrolyzing
                     O-glycosyl compounds [Evidence IEA];
                     GO_function: GO:0004556 - alpha-amylase activity [Evidence
                     IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-glucosidase"
                     /protein_id="HFG9697165.1"
                     /translation="MEKKWWQKEIVYQIYPRSFQDSNNDGIGDLQGIISRLDYLKDLG
                     ITSLWLCPIFKSPMDDNGYDISDYLDIASEFGSMEDLKELIKKSKDRGIKIILDLVLN
                     HTSDEHPWFQEALKNPESPYHDYYIFKKGNDLPNNWRSVFGGSVWEKVENRDEYYFHS
                     FGKKQPDLNWENPILRSELYQMINTWSQMGVAGFRVDAITFIKKNLSFQSLESDGVDG
                     LVKCTKTVRNQPGIEKMLYELKENTFKKYDCMTVAEAAGISYDQLGDFIGEDGFFSMV
                     FDFKHADLDVASGSEWFKRISWTIPDLRKCILDSQMYVQEHGWAANFIENHDQPRATT
                     KYLLQYERNDDAVKMLGAMYFFLRGTPFIYQGQELGMTNFKRDTINDFNDLSSIDQYY
                     RSIDEGYSEEEALEFVNLRSRDNARTPFPWADKENAGFSDTTPWLKVIENYKDINAQS
                     QINNSESILEFYKKMIKLRQDSEYSDCLIYGSIEPIDIESDDIIAYRRQLDLVVIDCY
                     YNFSDKPVEIRVEEKYDIVFQNLDDINLLNKTVRLKPFHAVLLKVR"
     gene            complement(21433..22254)
                     /locus_tag="ACGI5H_001455"
     CDS             complement(21433..22254)
                     /locus_tag="ACGI5H_001455"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HFG9697166.1"
                     /translation="MKLYKLLILDIDGTLRDEVYGIPESAKHAIRLCQKNHCSVVICT
                     GRSMGTIQDDVLSLGVDGYIAGGGNYIQYHGELLYNQSFNQRLIKEVVCLLKNREVAF
                     SIESQEKVFMNQKAKEIFETMNQLKGTNSCINKQHIQEKITYENNIEEYKSQDIHKIC
                     LWSNEKVFDEVKDILQDKMELAQRDISSQYYEIIQKDFHKGKAIKRLQERLGVTQKET
                     ICFGDGQNDIVMFQASDVTIAMKNSHQQLKDIATSICEDIFDNGIYKELKRRNII"
     gene            complement(22353..23117)
                     /locus_tag="ACGI5H_001456"
     CDS             complement(22353..23117)
                     /locus_tag="ACGI5H_001456"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434714.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MurR/RpiR family transcriptional regulator"
                     /protein_id="HFG9697167.1"
                     /translation="MKIEGLFNKYYNSFTANDKYICECILNHKEDCIKLSIDEFADKY
                     HISTSALSRFAQKLQLPGYSELRVIIRLNETEVEYKNQSKHQLMDCYNKVINDIEKKD
                     CSIMFERMKKANRIIVFGEGYSQERVAKEMKRIFLPTGKIIYDVYGYDMIQALNHFIK
                     TDDMIFFISLNGDASTIIDFAKEMRMKGIYMVSITKMISNPLARLCDENLYIQSISIS
                     VDKQLDYDVTTPYFILIELLYIKYKMYLESEHIPRK"
     gene            complement(23114..23863)
                     /locus_tag="ACGI5H_001457"
     CDS             complement(23114..23863)
                     /locus_tag="ACGI5H_001457"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426291.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MurR/RpiR family transcriptional regulator"
                     /protein_id="HFG9697168.1"
                     /translation="MRLESLVNQNYDNLNENDKIIIKQILICQREYRNFSCEKIANEC
                     NVSRATLLRLCRKIGLDSFSDLKYLLKNNQLEFVNNDNNFHDVCENYRLLMNELQKIS
                     FQDICKIIYDAETIYIYGTGNEQKSLAQEIKRIFLSVGKCVIDLFDIGEIEFMRESFQ
                     KSDLFIIISLSGETKAGIEIAKFINNHIHTISLTRLDNNTIATLCEYNLYVETQKLDT
                     LQAISYEVVGAFYALLDLLHMNYIEYRRRKE"
     gene            complement(24367..24972)
                     /locus_tag="ACGI5H_001458"
     CDS             complement(24367..24972)
                     /locus_tag="ACGI5H_001458"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426278.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HFG9697169.1"
                     /translation="MKIKENVLMLDSTRGSNCFIVFDKEIILIDTGLPFMGKNIIKEL
                     KTLGIKLTDIKHILLTHHDVDHISNIKLLKEKTGAKVWAHVEDIPFIIGEKDRPGFKK
                     FIGKAISRRLIKDVEPYGENMQIGNIKIIHTPGHTPGHVCMIFEDVLFAGDLVKNKNG
                     NIVPYPNPWNWDYKKMMKSIRELDNLKYEWICMSHGTPCIK"
     gene            25151..25789
                     /locus_tag="ACGI5H_001459"
     CDS             25151..25789
                     /locus_tag="ACGI5H_001459"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417472.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HFG9697170.1"
                     /translation="MSELSKRDKEKIQRENEIIDKAEKLFCLNGFDNTTMNELAKEVE
                     YTKRTIYKYFSCKEDLFFAVVLRGYKRLWDNVKIESAKGKTGFEKIKLSYFAFHKFYS
                     VEPSLLCLMGMIGIVNSEKSDTDMLFKEKFFSFNKFMFDEIQGMFEIGKNDRSIRHDI
                     EIPTLMYSSIFTLTGFFNLLSVTGKSYLNNFNIDEEKFIETTLALLIDSIKA"
     gene            25921..26583
                     /locus_tag="ACGI5H_001460"
     CDS             25921..26583
                     /locus_tag="ACGI5H_001460"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009901935.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000156 - phosphorelay response regulator
                     activity [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HFG9697171.1"
                     /translation="MAKILLLEDNDTITFGIKTSLEKKNHTVCCYNTIAEAKKNFDKT
                     IDLILLDLNLPDGIGYEFCQYVKSIEDTPVIFLTVRDDEKDIIRGLDMGADDYVVKPF
                     LLSVLQSRINAVLRRTHSNTNNTITCENISLNKVEVKAYLDNVEVPLTAGEYKLLLSL
                     MENKNRAMTRTKLLEMLWDVDGNFVNDNTLTVTIKRLREKLKNPPCIKTLRGIGYRME
                     DN"
     gene            26583..27764
                     /locus_tag="ACGI5H_001461"
     CDS             26583..27764
                     /locus_tag="ACGI5H_001461"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728749.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000156 - phosphorelay response regulator
                     activity [Evidence IEA];
                     GO_function: GO:0004673 - protein histidine kinase
                     activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0007165 - signal transduction [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HFG9697172.1"
                     /translation="MKTPRNINSTVVFIIFCLIVTFLLSVILTTITSFNEYNVLSKAL
                     GASYEYNPKSTESILKSLKNSSDKDFKTGNEILSKHGYSKSTFWSKNFFYFLVISFGI
                     ISTMATVVYIIKHRTNKQKLSRINNLTQYLEEVNLGKESVLLRCEDEFSHLEDEIYKT
                     VGELRCSKEFALKERQTLSDNLADIAHQLKTPITSMSLMAQLLSENCPDEEIDYINRL
                     TNQISRLERLVSSLLTLSKLDASTLIFESKLIDVHSLLTYAIEPIEGSLREKHQTFTI
                     EASPSVEFEIDINWTLEALLNILKNCSEHIEDGGYIVAYYSQNPLYVEIIIEDNGKGF
                     AQEELPYIFNRFYRGKNASKDSIGIGLALSKSIIERQNGTLHAENCHNGGARFIIKFY
                     T"
     gene            complement(27945..30605)
                     /locus_tag="ACGI5H_001462"
     CDS             complement(27945..30605)
                     /locus_tag="ACGI5H_001462"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728750.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="FtsX-like permease family protein"
                     /protein_id="HFG9697173.1"
                     /translation="MNILQEYTLDFVRRNKRSSIAIMLAILLTTTMMSSLCGLLYTMW
                     TDFIKLSIEKEGNWHGELFDYTYGSDLPLIENFSSVDDVMVKGQWYVGKINDEKRDYI
                     IYRNATSEYWNSMPEKDTIIEGRRPNNANEIALSKQYFENNPSVKIGDKITLPIGDRI
                     LNGKPLEPIAPKSKGESFKKISEATLTIVGKVDVSTSSVIPAYTALGYLDKTSIKPND
                     SITVYLRFKNIRDTYKELPKLAKSLGWKTNEYGKYNLKYNSNYLLKMLVFSPEQKASM
                     SSISKFSTPIMYLTIAIFTVAVFVMVIYNAFSLSANARLTQLGILSSVGASPKQIKRS
                     VVFEGFLLTIIPLPIGLFLGWLLCNRLIVYVNSVNYHTDVPEVVFTYGIPAFLPAVLL
                     TIVTVWISALIPARKVSKISPIEAIRQGDSVKIKKSHKYSLGKIFGIEGELASNALRA
                     RKKSYRTATISLTLSFLLLTCFLHIIANQEGAKAVYGSDNYKDQRDIAVYLENSEPVE
                     SAFIEKLDNTEGVKSSLYYQKMSASTWLTEKDASKELAKNGGFKNIASSKKYSPIERD
                     GKFRIISNIIGLDDKSFTEYCRQISVDPKLFYDTKNPTSIVYNKEEDINRSTRRNKVY
                     IDYLNLSIGDNIKLNEKVYDEDKGDYTYNMKVGAITSTLPKIVDTSSKYTLMQIVPMS
                     MVQEISKNYDEVSRLRSNRLIGVFKVNNREDIPRVREKLESIYNKDYGSGDYSIEDVL
                     ESEKQKASGIKTMNLIVGFITGLLAMIGLSNVLATVSGNIRSRRQEFAMLRSVGLSPE
                     GIKKMLILEGLFLGITPLLLSIPVQIGIVYAFLRINEIYFIEYLPFAPISTIIGFTIL
                     ILFIVIASYMTGYKQLKNENIVESIKNETI"
     gene            complement(30602..31285)
                     /locus_tag="ACGI5H_001463"
     CDS             complement(30602..31285)
                     /locus_tag="ACGI5H_001463"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426268.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HFG9697174.1"
                     /translation="MEILKCENLTKIYGSNQTRVTALNNVNLSVQKGDFVSIVGASGS
                     GKSTLLHLLGGVDRPTSGKIYVEDTEISSLKEEALAVFRRRKVGLIYQFYNLIPTLDV
                     RKNILLPMLLDKRKVDEDRFSEIVSILGLSDRLNHLPSQLSGGQQQRVSIARSLIYRP
                     AILLADEPTGNLDRKNSEEIVDLLNLSNKRFNQTILLITHDEKIALEANRIVTMEDGV
                     IVSEKVVKK"
     gene            complement(31629..32582)
                     /gene="blaCDD"
                     /locus_tag="ACGI5H_001464"
     CDS             complement(31629..32582)
                     /gene="blaCDD"
                     /locus_tag="ACGI5H_001464"
                     /EC_number="3.5.2.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434692.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008658 - penicillin binding [Evidence
                     IEA];
                     GO_function: GO:0008800 - beta-lactamase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="CDD family class D beta-lactamase"
                     /protein_id="HFG9697175.1"
                     /translation="MKRKKNFIWIAILLVGVVMVMYYVGKKHNDINQKTDKNYIKSEL
                     NKSELNKSKIENNNKNKKEKINMVDYSDCFEGISGGAIFYNTKNKEYNIYNKELIETR
                     RSPCSTFKIVSTLIGLEKGVINSKESVMGYDGTEYPNKNWNKNLSLEEAFKESCVWYY
                     KKLIDKVDAKSVQNILDDLKYGNCDISEWEGDLKNGKGHLNGFWLESSLQISPKEQVQ
                     TMAKIFEGDTNFKKEHINILRDIMKIDVNDKNINVYGKTGTGFDEKNKRVDAWFVGML
                     EREGDTYYFAIKSDDSNKEITGPKVKEIAINIIKKYYSVRE"
     gene            complement(33123..35237)
                     /locus_tag="ACGI5H_001465"
     CDS             complement(33123..35237)
                     /locus_tag="ACGI5H_001465"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434689.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="3'-5' exonuclease"
                     /protein_id="HFG9697176.1"
                     /translation="MSENKQVVNCDIIASNSKHNMCEYDAELLTFFPDEIAHLIEINN
                     KLDNAFKKAENLVDKLDKDYMDAKMYMVKNRGEIDPHEMFQNEQGLKQIDNYGAFMVK
                     VRDKINKIKDSPYFARIDFRLKDMDDESKYYIGRFAFDYEDELIILDWRSPIASMFYD
                     YEIGKAGYDAPIGWVDGEITRKRQFKIKNGKLEYALESSINIQDDILQKELSHTSDEK
                     MKSIISTIQKEQNQIIRNDKADTLIIQGVAGSGKTSIALHRIAFLLYRFKDKISANNV
                     IILSPNKVFGDYISNVLPELGEEPLCELSFENIAEVQLDRVINFESEKDPLEINDAKW
                     SERVRFKSTLDFVKLIDDYIKQMPNKIFIPKDYTFGSFTAKSDWIQSRFEAYNRYPVK
                     KRLEKVAEDIHYKFESDNIMEEDLPKVKSILKSLNGMLTIKNTLTLYKDFFKQMNISN
                     MFVMATKKTLEWSDVYPFIYIHAAYEGIQEDKIIRHVVIDEMQDYTPIQYAVINLLFK
                     CKKTILGDFGQLVNPNHTHTLDDMKQLYNDGELVMLNKSYRSTFEIINFAKKIQDISS
                     LEPIERHGEEPALLKCNNEQDEINKIKIEIEEFKKSDNATLGIILKTDNDAKAVYDAL
                     REKYSVHLISSESSSFTKGVSITSIKMSKGLEFDEVIVPSVNNKTYYSDYDRSLLYIA
                     CTRAMHKLKLTYTGELTQLIDM"
     gene            complement(35495..36355)
                     /locus_tag="ACGI5H_001466"
     CDS             complement(35495..36355)
                     /locus_tag="ACGI5H_001466"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888278.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_function: GO:0043565 - sequence-specific DNA binding
                     [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HFG9697177.1"
                     /translation="MSYKVINVITAIDYIEEHLSEKLDLDIVANAVHYSKYHLHRTFT
                     TSVGLTMHDYIKRRKLTEAAKLLVFSKKPIIEIALIAGYESQQAFTSIFKAMYKKSPN
                     KYRKEQEFYPLQLRFVLKKDNLFSKNVLELEKEIKLASMSDIPLWMNLVRLVIDGFPN
                     LQEEEYIYQLEQYILEERALILKLNNVAIANMVFNRETRSIDFFGIHPQYRNSDIAQV
                     FLKKVIEDFLIDTDISITTFREGDKADTGHRDMIKKLGFAEAELLVEFGYPTQKFILP
                     CVEERDNRQN"
     gene            complement(36950..37312)
                     /locus_tag="ACGI5H_001467"
     CDS             complement(36950..37312)
                     /locus_tag="ACGI5H_001467"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434678.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HFG9697178.1"
                     /translation="MKIYDILTRFYIQDIEKAIPFYENLLKEKCSLRFSYKEVGLELA
                     QIGNVLLLSGSDDALKPFIETKSTFMVDSVDEWRSYLLDNGAVVVRDKKKVPTGYNMT
                     LRHPDGTIIEYVQHTKQD"
     gene            complement(37546..38010)
                     /locus_tag="ACGI5H_001468"
     CDS             complement(37546..38010)
                     /locus_tag="ACGI5H_001468"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860814.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GyrI-like domain-containing protein"
                     /protein_id="HFG9697179.1"
                     /translation="MTRISNITIAEQSEYCFLAIRKTIDFMVEFSEFSKQSFEKISKY
                     LEERGILSSGAPIVCFHNMDLAKLDVEVGFPVATYIDGKNEILQRIVPAQKIITAIDL
                     GPYELQDPTLEDLFSWANSNGYKLHGDIYYQYLNDINRPASEYLTKMMLPII"
     gene            complement(38439..39860)
                     /gene="nhaC"
                     /locus_tag="ACGI5H_001469"
     CDS             complement(38439..39860)
                     /gene="nhaC"
                     /locus_tag="ACGI5H_001469"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009901909.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0015297 - antiporter activity [Evidence
                     IEA];
                     GO_function: GO:0015385 - sodium:proton antiporter
                     activity [Evidence IEA];
                     GO_process: GO:0006814 - sodium ion transport [Evidence
                     IEA];
                     GO_process: GO:1902600 - proton transmembrane transport
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Na+/H+ antiporter NhaC"
                     /protein_id="HFG9697180.1"
                     /translation="MKERECRKASLFDAMIPITCLILFLSLGVLVYGSSPHVPLIGAA
                     AVAGLVAVYRLGFKWKELELSMFNSIKMAMQAILIIIIIGVLIGTWIVSGVVPCMIYW
                     GLKILSPNIFLVASTLVCAIVSLATGSSWSTMGTVGVALLGIGQSLGMPIGLIVGSII
                     SGAYFGDKLSPLSETTNLAPAMAGTDLFTHIKYMLYSTIPSLLICLVIYGVIGMKYSG
                     QALDIKQIELIRSTLDSTFNTLSPVLLLAPAIVIGLVVFKVPAIPGLIVGAVLGVLFA
                     VVFQGESMNTILDAAQNGYVSSTQIQEVDALLSKGGIMNMMSTVSLTICALSLGGILE
                     KTGMLEVVASSLLRLAKGVFGTVLCTMVTCTITNIIAGEQYLSIVIPGRMYNKEYKKR
                     GIHPKMLSRALEDSGTLTSPLVPWNTCGAYITATLGVSALTYGPYALLNIINPIVSLV
                     LIACKFKIARIEDEPETCLNFDV"
     gene            complement(39890..40954)
                     /gene="orr"
                     /locus_tag="ACGI5H_001470"
     CDS             complement(39890..40954)
                     /gene="orr"
                     /locus_tag="ACGI5H_001470"
                     /EC_number="5.1.1.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728754.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ornithine racemase Orr"
                     /protein_id="HFG9697181.1"
                     /translation="MYPRLEIDIEKLKHNAKLISQMCHERNIKISFVTKSFCAQKEIV
                     EEICSEGIDHIADSRIQNLKNLQDINLPKILIRIPMLSELEEVINYCDISFNSELGTI
                     KKLNELCESKNIIHKIVLMFDLGDLREGYFYEEDFFSNVREIVRLKNIEIIGIATNLT
                     CYGAIIPSRENIGRLVSIAKRMEEKFGINLEIVSGGNSSSIHLLINNNMPEGITNLRI
                     GESILLGRETAYGENINGTYQDAFKLICQVVECKEKPSVPIGEIGVDAFRNKPVYEDK
                     GILKRAIIAIGKQDINIDSLIPIDTDIKILGASSDHMILDVSNTKYDYKLGDNLEFLL
                     TYGGIMSSSTSKYVSKKIIV"
     gene            complement(40939..42348)
                     /locus_tag="ACGI5H_001471"
     CDS             complement(40939..42348)
                     /locus_tag="ACGI5H_001471"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417439.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GlmL-related ornithine degradation protein"
                     /protein_id="HFG9697182.1"
                     /translation="MENSKVSLKIDVLVAEIGSTTTVVNAFHDINTNNPIFLGQGQAP
                     TTVFEGGDVRNGLSGAIKDLANKLSVDDIEYNDMFATSSAAGGLKMTVHGLVYDMTVK
                     AAKEAALGAGAVIRQITSGRIKRTDLNKIKEINPNIILIAGGVDYGERDTAIYNAEMI
                     ASMNLGIPVIYAGNVENQEEIRLIFEDTNYKLYITENVYPKIDLLNIEPTRRIIQSVF
                     EEHITTAPGMKYIKEMVNENITPTPGAVMEASKLLYKNIGDLLTLDVGGATTDVHSVT
                     DGSDYINKILVNPEPTAKRSVEGDLGVYVNMKNIVEVIGKENLQSELSIDIDAVIENY
                     PPIPKSKEEILFVERLTKEAVVKAMLRHSGKIRNIYGTTGKVKIAEGKDLTEVRYIVG
                     TGGALTRLPSRIEILDNMLKYNKNNELLFPKEKTKILIDNDYIMASMGVLSKKYEEAS
                     LKLLLKSLNFEEERLCILG"
     gene            complement(42348..44552)
                     /gene="oraE"
                     /locus_tag="ACGI5H_001472"
     CDS             complement(42348..44552)
                     /gene="oraE"
                     /locus_tag="ACGI5H_001472"
                     /EC_number="5.4.3.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892628.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-ornithine 4,5-aminomutase subunit OraE"
                     /protein_id="HFG9697183.1"
                     /translation="MLKENKKLDIDYILKDLDKYKPKRRGWVWREHLENLEMGPFKYK
                     DCTKPLKKSVGLPSSKYFNNIDPQPSPVITTEIASGRFEDDIRRMRMAAHHGADHLMV
                     IRTAGQSHFDGLIEGTPQGIGGVPITRKQVRAQRKALDFIEEEVGRPINYHSYVSGVA
                     GPEVAVMFAEEGVNGAHQDPQYNVLYRNINMVRSFVDACEAKKIMAFANIAQIDGAHN
                     ANATAREAWKVMPELMVQHALNSIFSEKIGIDKSNICLSTVPPTAPPAPCLKIDLPYA
                     VALRELFSDYKMRAQMNTKYMESSTREATVTHVLNLLTSVLTRADIQSTITPDEGRNV
                     PWHIYNIEACDTAKQALVGMDGLMDMIELKDVGELRDKARELKERAVLYMEEISEVGG
                     YFESVEQGFFVDSGNYPERNGDGISRKIKGGVGEGTVYEREEDYLAPVTAHFGYNNVA
                     QYDENAIDNPSMLIDGCTFENPDKIIYIDELDDFDNVENRLKESYEYRNGTKIKPEME
                     WCADGIVMITMMLPTDKRTAEFAALEFVKKMNLQEIEVISREVMHESEGTRIEVKGRV
                     PFDIDLNNLVIPEEPKVLTDEEIRADIEEKPMKIVSATVGEDEHSVGLREIIDIKHGG
                     IEKYGIECHYLGTSVPVEKLVDAAIELNADAILASTIISHDDIHYKNMKKLHDYCVEK
                     GIRDKVMIACGGTQVTPEIAVEQGIDAGFGRNSKGIHVATFLVEKRREMSNK"
     gene            complement(44546..44920)
                     /locus_tag="ACGI5H_001473"
     CDS             complement(44546..44920)
                     /locus_tag="ACGI5H_001473"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417434.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ornithine aminomutase subunit alpha"
                     /protein_id="HFG9697184.1"
                     /translation="MKKREDDFEVRRKHLQELSDDELKERFWSLATQIVEPMIELGKK
                     NTTPSIERSVLLRMGFSSLEVKPILEGVMERGLIGKGAGHVVYKLAKSKNITVREAGL
                     LLVKGEYWDEVTCLFREGVESC"
     gene            complement(44998..46428)
                     /gene="ortB"
                     /locus_tag="ACGI5H_001474"
     CDS             complement(44998..46428)
                     /gene="ortB"
                     /locus_tag="ACGI5H_001474"
                     /EC_number="2.3.1.263"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888273.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-amino-4-oxopentanoate thiolase subunit OrtB"
                     /protein_id="HFG9697185.1"
                     /translation="MNNSTSMKDMSYQAVMGRNNEIMKNAIGLDYSYFEQEGIGFDYE
                     KMMSETGYTLQDIEAIQSQYAVGNTPLIELKNLTKLARKCAKEGKGARIFVKDEAMNA
                     SGSFKARRAATAVYHAKQMGYKGVIAATSGNYGAAVASQAAMQGLKCIIVQECYDSNG
                     VGQPEIIEKARKCEAYGAEVVQLTVGPELFYTFLVLLEETGYFNASLYSPFGIAGVET
                     LGYELAIQFREKYKKDPDIVVCTNAGGGNLTGTARGLIKAGSINTKVVGASVDLKGLH
                     MASDNQFNKKSFTTGHTGFGIPYCTWPDRSDVPRSAARPLRYMDRYVLVKQGEVFYTT
                     ELLAQLEGIERGPAGNTSLAAAFSLAQELDEDKVIVVQETEYTGAGKHICPQLTFARE
                     NGIDIKFGNPREEIAGVNLILPERPELLKCVDIDMNKIRKSFIKNCISNNHIDNIDKL
                     SNRDIEFLMEEVKSSRDFVVDVLNNL"
     gene            complement(46421..46729)
                     /gene="ortA"
                     /locus_tag="ACGI5H_001475"
     CDS             complement(46421..46729)
                     /gene="ortA"
                     /locus_tag="ACGI5H_001475"
                     /EC_number="2.3.1.263"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426242.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-amino-4-oxopentanoate thiolase subunit OrtA"
                     /protein_id="HFG9697186.1"
                     /translation="MDAKINDWVIIHNIVLTPEERAPQVPEDTKKVSLEMWVKGFIQS
                     DASIGDLVEVKTITGRLVKGNLLKINPYYTHDYGKCIPELLQIGIQAKEILFGGVYNE
                     "
     gene            complement(46873..47940)
                     /gene="ord"
                     /locus_tag="ACGI5H_001476"
     CDS             complement(46873..47940)
                     /gene="ord"
                     /locus_tag="ACGI5H_001476"
                     /EC_number="1.4.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434659.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2,4-diaminopentanoate dehydrogenase"
                     /protein_id="HFG9697187.1"
                     /translation="MRKVRVGIWGFGAMGIGMANMILKKEGIEIVSVCSRSTSGKSMY
                     NVLGIERGERPEVIINKNYEEVFREKSVDVVLLATDSFTKKAFDKIIFLLNRKINVIS
                     TAEQMAYPQADDADLAKKMDEVAKENGVSILGTGINPGFVLDLLVLALSGTCEEVTSI
                     KAKRVNDLSPFGKSVMEEQGVGVTREEFIKGVEDKTIAGHVGFVESINMIADGLGWKL
                     DKIEQTKEPIMTTVDRKSKYGEALAGNVAGCRQCGYGYVNGEVLIEMEHPQQIIPEAE
                     GIKTGDYVSIKGIPNIDLQINPEIPGGVGTYAMIVNSIPLIINARPGLKTMLDIPVPR
                     AIMGDIRNQIEVELEEESKAN"
     gene            complement(48196..49596)
                     /locus_tag="ACGI5H_001477"
     CDS             complement(48196..49596)
                     /locus_tag="ACGI5H_001477"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728757.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-54 interaction domain-containing protein"
                     /protein_id="HFG9697188.1"
                     /translation="MNQEIFFKIMNEILENIDEGVHFVNKDGKTIIYNNSVQKMEKMN
                     RHDILTNSFFDIVNKMKINRSTLLEVLEKREVIKDNIQKYLDKNGREITAINTTIPID
                     IKGEFVGALEISKNMTTIENLLNRNYKKNLVNKVSIRQKKGYEFDDILGESNLIKEAI
                     AKSKKACKSDASVFIYGETGTGKELFSQSIHYGSNRKNYPFIAQNCAALPESLFEGIL
                     FGTSKGGFTGAIDRPGLFEQANKGTLLLDEINSMPIMLQAKLLRVLQEGYVRRVGGTK
                     DIPIDVRIIATTNESPKVILNEHKMRKDLYYRLNIIHIKIPPLRDRKEDIPLLCKKFI
                     SKYNKKLNKKVVGISDEAIKILKNYDWQGNIRELENIIYCTMSMMEDEVQIETSMINL
                     NDYYNLKENKESNNYSLNDLEDKTLSKIISEIEEKYIYESLEKASYNITKAASILGMN
                     RQNLQYKIKKYNIKIL"
BASE COUNT        16844 a         8383 c         5907 g        18544 t
ORIGIN      
        1 actttaatga ttaagttttg aaatataact aagaatttga taatttattg agatttttat
       61 actaaaatat acatactata caaacttaat ttagaaggga gcattcttat gaacaataaa
      121 atactcgtcg tagatgatga ggaaggtata ataacactct taaaagatta ctttgaaatg
      181 aatggttatg aggtttacac tgctcaaagt ggaaaagacg cattaaaaaa aatatctaaa
      241 aatccagata tcattctact tgatataaac atgcctgaaa tagatggaat tgaagtttgt
      301 aatagaatta gagattatgt atcatgccct attctatttc ttacagctag aattgaaaat
      361 actgacaaga taaatggttt tcgtgctggt gctgatgatt atattgtaaa accttttgat
      421 ttagacgaac ttggagctag agtatctgcc catttaagac gtgaacaaag gaagtcaaat
      481 caaactaaaa ttaaatttta taatgattta acaatagatt acgaaaaaag gttaatttgt
      541 atatataata atcagatttc actttcaaaa aaggaatttg atatagtaga gcttctctct
      601 atgaatcctg gacaagtatt tgataaagaa aaaatatatg atagagtctg gggatacaat
      661 agcaatggaa atagtgatgt tataatggaa cacattagaa aaatacgaat caaactatca
      721 aaacatactc ttgaaaatta tatagaaaca gtctggggag ttggttataa atggataaaa
      781 taaataatat gtcattaaaa aaagctttct ttgttcttac tttatcttca ctaattatag
      841 catcagtgct tactactttc gcatacattt tacttaataa tctatataat tctatacaag
      901 ataagtattt aaaaacacct ataaatacag gtattataac catagttcaa aacaatgtga
      961 accaatttag tgattatgat aaaacattac ttaatataat caacatactt cagcttgtac
     1021 ttccacttat cttttttata ggacttttat tattagctga tataattttt tacaaggtaa
     1081 aattaaaaac acccatagaa atactcaata aaggtgcaat ggaaatatcc aacaacaatt
     1141 tagacttttg cttagaatat aataataatg atgaattagg taatctatgt aatgcttttg
     1201 aaaaaatgag gtctgaacta aataaaaaca acataaagat gtggactatg attaatgata
     1261 gaaaacaact taatgctgct ttttctcatg atttaagaaa tcccctaaca gttctaaaag
     1321 gttactcaaa ctatttaaca aaatacatac caacaggtaa gcttagtgat gagaagattt
     1381 tatcaaccac acaacttatg tctgagcata ttaacagaat tgaatactat gtagaaaata
     1441 tgagtaatgc tcaacgatta gaagatttag ttgtttcaaa atctatgtcg aatataaaca
     1501 agtttataga aaacttagat gaaaatatat ctatcattgc taaacaagaa ggaaaatctt
     1561 ttacacttaa aagtcaaata aataatataa atctattttt tgatgaaaat atcattctta
     1621 gagtcgtcga aaatataata tcgaatgctt ttagatatgc tagaaataat gtatccatac
     1681 ttatatatct tgaacaagaa ctccttacct ttgtaattga agatgatggt ataggattta
     1741 gtaaggaatc tctaaaatta gctttaagac ctttctatag agataagact ttaaatgaca
     1801 gcaatgcaca ctttggtatg ggtctttata tctcaaaaat attatgcgaa aaacatggtg
     1861 gctctatttc tattgaaaat aattctacta acagtgctaa aattactgct aaattctcaa
     1921 caagaaatta aaatgatttt gtaagctttc actgttctta tataaaattt gttagtttag
     1981 aatttataaa atgtatttca atttacaacc aatatatata ctattttgta gaagttgtaa
     2041 gagttgcttc aattataata tttggcaaaa ggcatttgaa ataataatag aaatatatat
     2101 ttaaatatgt agaatagtat gaaattagaa ttttggaggt gattatatta aaagttttgc
     2161 taataatatt acattctctc gtattgtgtt tgcattgcta atgcttagtt ctacattctc
     2221 ttcactgcct ttctggatat gttatttttg gtgtggaatt agtgatatac ttgatggtct
     2281 tattgcccga aagttgagac aacaaagtgg aataggtgca aagttagata gtattgctga
     2341 tttcattttt gcggttacaa ttttggttac tgtcggaaaa aatattgctc ttcccatgta
     2401 tctatggtgg tgtattgttg caatagcatt gttacggttg attagttaca gtattggttt
     2461 ttttaagtat cgcacatttt catcgcttca tactttgatg aataaaatca ctggaatttc
     2521 tatctttgct tttccattac tctatatttg ctttggtctt gatgttgcag gaattatgat
     2581 atgtatcgtg gcttttcttt cttcttttga agaaatagca attatgataa aatcaaaaga
     2641 attaaatcgt gatataaaaa gtatatttat gtgacaactt agaatttgtg acaaaaataa
     2701 tttatataat aatgaggaag taaaacataa aaaattatcc acaagtttat gtgtaaaata
     2761 gttttaaagc aatagagttg tattgtaaag cctttagtgc ataaattaca ttttaaatta
     2821 aaaatgatac tgaaactgct tatcagcact gcgaattatc cgcaaatagt gaagactttt
     2881 tagatttaag ctaaaagttg ggaaaaaatt gagttttaaa acttacactc ttcttatata
     2941 gaaaaggaga gtgtttttta tgattataaa agcaaaacaa ttatcaaaaa tatatggttc
     3001 taataacaat aaagttatag cacttaataa tgtaaattta gaaataaact caggtgaatt
     3061 tgtttctgta attggacctt ctggaagtgg aaaaagcaca cttttgcata ttttaagtgg
     3121 attagataat cctacctctg gacaagtgtt acttgatgat aaagatatat ataaacacac
     3181 tgaaaaagaa ctatctgcac ttagaagaaa atcctttgga ttcgtctttc aacaatttaa
     3241 tcttttacct gttcttacag catctgaaaa tatttcaatg cctgtacttc tagataaaaa
     3301 acaacctgat aaagactatt taaatgaaat ttcatcatta cttggaattg cagatagact
     3361 caatcatctt ccccatgaac tttcaggcgg tcagcaacaa agagttgcaa ttgctagagc
     3421 acttattgca aaaccagata taatatttgc tgatgagcct acaggaaact tggacagtaa
     3481 aagtggcagt gaagttatga atcttcttat aaaaacttca aaacagtttg gaaagacttt
     3541 agtggtaatt actcatgatg atagaattgc aaaacttgct gatagaaaaa tttcaattat
     3601 tgatggtgtt cttatggagg tgaaatagaa atgaagaatt acctttcact ttcaataaaa
     3661 gaattaaaaa gccagaaatt tatgactaca ttcatcatta tagcaatagt actatcaact
     3721 attatgacaa ctgtggttgg acagtcaatt ggtatcctac aaaatttaag aattgaacaa
     3781 gcccgttctt ttaatggtga tagacatgta tcctttcacc aactcactaa aaatcaagtt
     3841 gatgacataa agaaagatga tagagtttat caagctggta cttcaataac tattggcagt
     3901 agtaaaataa aggattctgg tatctctgta cttgtaaaag agtatgataa aacaggactt
     3961 tctaactacc caaaattaat gaaattaaaa tctggacatt tgcctaaaga taaaaacgaa
     4021 atagccttag atgaaaacac actaaagctt atgggtataa aaccaagact aggagtgact
     4081 atacctatga atttagatat ttcactttta aatgatacca taccaccata taattacaca
     4141 gctaacttta aattgagtgg cattttagag gatgattata caggatatgt aagtggtata
     4201 gtaaatggta ttgtaggtaa aggtacatca gaaaatctat tacctaagag atatatttta
     4261 tcctctttgg attttaaaat aaaacagcaa gaaaagtttc aagaaatagt aaatcaatta
     4321 gctaaaaaaa taaatctttc tcacaattca attcaatata attggattta cttaaatgct
     4381 cttaagatac agtttgaaaa agatgaaaat agttctaata gtgatggtat atctatgatt
     4441 atattggtat ctttatttgt tgccttattg gttttactgg cttctggact tgtaatttat
     4501 aatattttaa aaatctctgt tacaaagaaa attaaagagt atggatgttt aagagcaata
     4561 ggagctgaac caaaccagat atataagata gttattttac aaatcttaat tttatgtact
     4621 gttgccatac ctattggagc tgtaattgga attatatctt ctaaaggcat aactggaatg
     4681 gtcactaata tcttaaatcc agatatactt ctagcaaatg ataataaaga aattactgag
     4741 cttatacata aaaatacaac agcatatata ttcccattag tattaagcac taatgtatct
     4801 ttgatttttt catttatttc agcattacca tcagcaatat atgcttcaca tgtctctccc
     4861 aaaattgcta tggttggtag tactaccaaa atcaaaagaa aaattaaaag agaaaaaaca
     4921 ataaaaaact ttgaaagaca tctagcatgg ctaaacttaa aaagaaataa aggaagaact
     4981 ataataacta tactatcatt atttatgagt ataacagtat tcgttgcact gagtgagttc
     5041 tctaatgtat tagatgtatc taggtcagta agtaatttaa aagaaggaga tttttcctta
     5101 acaaatgaaa tatctggttt tgataaatca acactagata aaatagctaa aatgaaaaac
     5161 gtcaatcgca cttcctttat aaagtactct gaatacaaac agggtgaaat agatacagat
     5221 ataaattttg aaaatagtgg tgagatgtta aaaatcattg gaattgatga gcaaacttta
     5281 aaagacttaa tgccttctat tacagattct atactagaag actttaaaaa tggttctatc
     5341 tgttttataa aaaatccgat tgctatttct acaccaggtg taaaaactag atatacaaat
     5401 ttaaaaccta aagatagtat cacaatcaac aaaaaacaac tagatatata tagtacagta
     5461 gataaaatgt tctttttaca aggcaatggc tggataaatg gtgttgatgt tattgtatat
     5521 gattctgttt ataacacttt gacaaataaa aacaagttca accagataaa tatttatgct
     5581 aaagataaat caaaattaga acaaataaga ttgtctattg aacagatttg tgaaaataat
     5641 cctggctctc attggatatc atatattgaa tcagataaac aacttaaaga gagttttaaa
     5701 caaatagaat ttctagcatg ggcagttata ttatttgtgg gattgattgg tactttaaac
     5761 atcattaaca caactcatac aaatataaat actaggacta atgagattgg agttaaaaga
     5821 gctattggta tgagtaatag gagcttatat aaaatgtttt tatgggaagg tgtttattat
     5881 ggaatttttg ctgctatatt tggttcaatt gctgggtatg ccagtgctat tatcataaac
     5941 atggcaacta tagaaaagct tgatttcact aatataccaa ttacttcaat tttacaagct
     6001 actattattt ctgtacttgc atgtattata gctactctta ttccgttaag aaaagttaaa
     6061 aagatgaata taattgactg tatagatatc aatttataac tattttacag ataataatat
     6121 aaattaaatt atcaatgact gtctctattt tctttcaaat ctaactaata aatcttttta
     6181 actataatat aagctttaaa aaaggcctgt ctcaaaatag agataagcct tttttcattg
     6241 tcgaaataat gaaaatatat ttaacttcac aaaaaaagag tgcctcacga attaaaaatt
     6301 tcgctttgag acactctcct ttaatttaaa atatatagtt aaatgctatg ccaaaatttc
     6361 acacatgctc cacctgattt tgaattttct attttaacag aacctccaag ctgttccact
     6421 aattgtttga caatgtaaag cccaagacca gaatgtccac cttttgtctg cctagcttca
     6481 tctcctcgat aaaatttatc aagagccttt tttaaatctt tagagctaaa ccctctacca
     6541 gaatcacaaa tctcataaga aatacaattt ttttcatcct ttacagtaat actaatatta
     6601 ccacctgatg gagtgtattg cagactgttg gatatgatat tatcaaaaat tcgtgtcaac
     6661 ctatcaacgt cgatttgaat tggggattgt atattcccct gcattttcaa tataagttca
     6721 acttcctttt gatgagcctg taattcatag tcttgcacct tttgcctcaa aaattcaggt
     6781 aaatttatag gaacaagatt taattgtata tttgactttt ctaagtcaga cgtatattgc
     6841 atcttttgga caagagcagc acttttttct gtattttctc ttatcactgt aagataccta
     6901 tgaagttttt cattgtcatc tgtattatta ccaataagtg catctgtata tcccaaaata
     6961 atagaaagag gagattttaa atcatgtgct agagcttcca ccatttcaac acgttcctgc
     7021 tccatcttcc actgtgcaga taaagagcct tttaattcgt ctttcatttc agaaaaggca
     7081 ctacaaagtt taccgagttc attatctgaa taatagtcga tttcaaaatc aaggtccttt
     7141 tcttttatct tcttggacgc atcaatcaat agatgtaatg gttgattgat attctttaca
     7201 aagcgcttag aaagccatct agtaaaaccc acgatatata gaaatggaga aaacaaagcc
     7261 attataataa ctgcaaatac aaatctccct ctaatatttg caaaggtgat tttcacttgg
     7321 tagaatagaa taacagcacc ctcaatcttt ccattatccc ctttgattgg aacagtatgg
     7381 atataaccac ctttacgaac agttttattg ataaaattat taaataattc ttcttttgtt
     7441 ttaaatagtt ttttggggtt agtaccatat aaaatattgc cattattatc cacaacttga
     7501 tatagcatat catccccacg aatcgttctt tttaaacctt cttcattcga ttgtgataac
     7561 aaagctatgt ttttttcatt gatgtatttt tcaattctag gaacttgtcg ctcataatag
     7621 tttggtggat agatatcctt atttaaggaa tgaatataca aatagagagc aaatacataa
     7681 gtaatcactg tggcaactat actggctatt ataataaaaa taaaagtatg tctaaattgg
     7741 gtaataaggg attgattttt catttaataa cctctctctc tttacatttt attccactta
     7801 tacccaatac cccaaactgt ggaaatatat tctttttctg gtgtcacagc agaaaactta
     7861 gctcgtattt tttttactcg ttcaacaaca gttgaggaat caccttcaga atcacacccc
     7921 catacttttt catagatttg ttctcttgag aaaacttgtc ctgcatggag tgctagtaat
     7981 tcaacaatat catactctat ttttgttaaa tcaatattct taccatcaat tttaattgca
     8041 cgttccttca tatataagca taacttccca aaatacaaag tagatctctt gttctcttca
     8101 ttgatatact gtgaacgctt ttccctacgc agattagctt caatccttgc cataagttca
     8161 cgcagtccaa atggctttgt tacataatca tcccctccaa aggtcaaccc tttgattttg
     8221 tcggtttctg attgctttgc acttaaaaat ataattgggc ataaaacatc atctctaatt
     8281 gcctgacata cctcaaatcc attcatttta ggcatcataa tatccagtat aataaggtca
     8341 ggctcctgtt ttgataactc tatacctgcc tgaccatcat aagctatcaa cacttcatgt
     8401 ccttttgcct tcaattcatc ctcaagtagc attactaggt ccatttcatc atcaataatc
     8461 aatattttac tcaatataac accacctttc tcttatggga aggtcagtat taaaacaata
     8521 ttcgtctact cataactttt ccttccctcc cacattttaa accaaataac gcctcctatc
     8581 aagaatataa tcaaacctat tgctactact ataagctcta tactagctgt ttgcatcact
     8641 ttagagtaaa atgcctcagt tgaaatagtt ccagcttctt taataaaata aattcctgga
     8701 agcataccta gttttactgg ccatgtccat ggaacaaatg cccatacttt ttcaccaacg
     8761 ctagttaatc caagtattgc tgccatcaaa attccaccaa tactaatacc aatagatgca
     8821 cccatacccc atgcaaaact cacccaaaga tgaatagcta atagtggaag tgtcccaatc
     8881 accacaagtc ctgctgctga caggaataac catattgttg ctccagatgg cactgcaata
     8941 ctcattccta tgcaaagtat caacgtagca ataaatgtgc atatagttag gcaaaacaga
     9001 agaaaaagaa attttcccag atataatctg acacgagaaa tacctacaca taaaaaacca
     9061 ttaaaatttc cagcaagctc ttcctcctgc actataaatc ctgctaaaat acctactcca
     9121 ataggaatga tgaatacagt ccatactgta aaaaatcctt caaaagcaaa ttcttgtgta
     9181 cttccagatt tagttgtgag ataaaaaacc acacataatg aaaaaataat aggcatacaa
     9241 agagtaagcc actggacagc tgtcctcttt gctcgaagcc attctgatga taatagtttt
     9301 atcatttgtc atccctccta ttgaaccaag ctgcagtaag tgctgttaat actataaaca
     9361 caaccaaaga aacaacaatc ccaataggaa tcactgaagt attcaaaagt gggtctccag
     9421 cttctaatat agtaccgtta ggatgtatgt tgatgattgg gcataccatt ctaactgccc
     9481 aactccaagg tactgcaatc caaaatggtt ttgtcgcagc aagaacacca aatatcatac
     9541 ctaaagctcc aactcccata cttaggaaca tacctttcca tgtagctagc catagctgaa
     9601 gtggaagtat agcaagagaa acaacccagc atacaatact tgcccctata atctgtccaa
     9661 aaggaactgg accagctttc aatattaaac cagttataat tgttacgact attaaaacta
     9721 gcgttgaaat aaaactgtag actgccatag ctataacttt attaatccaa agtgtcatag
     9781 gagacacatt gtgtgtacgt aaagcacgat aatttccagc ttttttttcc tggaaagcta
     9841 ccaaagtagc gaacaatgca aatccaatag gcagaaataa aaatgaccac cagttaaaaa
     9901 ttaatgctaa aagattttgc cacgcccaag aagttgtttg agataatgga ttttgcatga
     9961 gtgttgattg cattataaat gcatatgctg caaaagacac tgggaaaaaa acaataagtt
    10021 tacccataaa tgttctttta tactttaaaa gttctgattg taaagcattc atctgttttg
    10081 tcctccttta agaataacat ctgtaaaaaa ttcttctaga ttttcattag ggtcaggcat
    10141 tccttgaaat aatagtcgtc ctccatttat aattcctata ttatctacaa cttgagcaac
    10201 ctctgataga atatggctag aaagaattac agttatacct tttttgggaa aagaagcaat
    10261 caattcacgc aattcttgaa tgccaaaggg gtcaagacca ttggttggtt catctagtat
    10321 taacaactct gggtcactca aaagtgcaat agctattcct aacctttgtt tcatacccat
    10381 agaaaattgt gaagctctct ttttacctgt atttttcaaa tttactattt ccaacacttc
    10441 ataaatttta tctttaggta ttcccaatat ttttgtatgt actaacaaat tttcctctgc
    10501 tgtaaggttt ccatacaatg caggggattc tattaaagaa cctatttttg caagagattc
    10561 tcgtttccaa ggctttctat caaaaataat acgaccattt gttgggcgaa gaagaccaac
    10621 aagcatttta agtgttgtgg actttcctgc tccatttggt cctaaaagtc catatatact
    10681 atttcgttca atttgtagag aaacattgtt aactgccatt tgttctccat atctttttga
    10741 taagtttttt gtttcaagaa ttaaatcttt catattaatt tctcccttct tgtaatacct
    10801 taaatctgtt actaagagaa tactaacatg aaaaaataac aattctataa cacctactaa
    10861 ttttaataaa atttaaaata aaaaatagag ttaccaattt tattttggca actctattta
    10921 agtttatgtt ttacagttat attagattta aacttagttt cattatcaca ctaacttcaa
    10981 atttactcta taatctttaa atcaaacact aatttattaa tcaaacacta atctattaat
    11041 ttatatttct ttagacatct aatatagttt gctactaaat aataattatt tatatcatat
    11101 ttatctaatc ctttaaaaga agttatttca tcattaagct catcactacc ttctacaaaa
    11161 acacaacctg tttcaaattc catacctaca ataatcttac agtcactata aatttcctct
    11221 tgagtatcgt acaatttttt tgcatttcct tcatttggaa ttgtaaatac aataggtttt
    11281 aattctttat cactggaaat cttttgtgaa aaaggcttgt ttaacttaat attattgata
    11341 actacatgtt taaattcctc tgaagtttct tctactatta catattttcg ctttaaaaac
    11401 tctattattt ctaaaacaga cttagaattt acttttaaaa tacttttata tttttcatat
    11461 aaagatttcc actgttcaat tttttcctgt ggtatttctt ggatatgtgt acttattttt
    11521 tcttgagata tttttttcaa ttaaactctc ctttcaatac ttaaatatcc ttatgaatct
    11581 cacatgacta aagttacaag gtttctactt aatagaattt tgcatactta aatatgtctt
    11641 attaattctc tacaggatat ctccgtagtt cctacgattc ttacataagt tacttatttt
    11701 aaattgttat tagttatatt ctaaaaatta tttattttat cactaatata atactcttaa
    11761 aaactttaca aatcaattta aatttgctac cttttattta taacaactta tagtacattt
    11821 ctcctatgct tttcaatata ttacttttaa aaggaggttt tcattatgat tttaaataga
    11881 gctgagcttt tccgaggata ttctttaaat agatttaacg agatatgcaa tatattatca
    11941 gtaaataaaa ttaaatataa gtataaagtg aaaaataatg cttactctaa aaaacctttt
    12001 tttaatgaaa taacacttgg caatttaggc caaaaggaag atttctctta tgagtactta
    12061 atttatgttc ataaagacga ttatgaacag gcagagtctc taataaattc taagttgcga
    12121 tagattatct ataaaacatg acattctgtt gtcatgtttt atatgttatt atactttcaa
    12181 atatgctact atattttcaa aattgtgtgc tttaaaacta gcttttttta gtaatttaaa
    12241 gcttaaaact aaggagactc gttatatgaa aataaatata aaatcaaagt taagtgaatt
    12301 tattaaacag aacaatcttt ttgatgacag cagaataata tcctatcttc ctaatataac
    12361 aatagaaaca gacaaaataa aaactataat gattaatgag gttgtcccaa ctaacaccaa
    12421 tgacgatttt tatagtgtag ataaagatgc tgattattta aaaactacta ttcctttatt
    12481 tgacagtgca ggaataaaag tatctaacat aaatgatatc ctagatatgg gtatctatat
    12541 aactaatgca gtaaaacttc ctaaatcaga atatacaata actcgtgata caattaaatt
    12601 acatatgcct attttagaag aagaaattaa attatttaaa aacctagagg tagtaatgtt
    12661 aatgggagat gttgcaaaaa aatcttttaa tatgattact aaaaagcata taaaaaagaa
    12721 tgtcatccct tccatttcaa catataaact tcgtaataat gaactttatt atgataattt
    12781 aagagtattt ccatcatata ttatgactgg tggaaacata ctgattgaaa aatcaaaatt
    12841 tgaaatggca tcagaagata taaaaaaaat gttcgagatt ataaacggtt gatattacaa
    12901 aataataaaa actaatataa aataaaaagt gcctcaaaaa cttctattta tgaggcactt
    12961 ttattttata ttagtgtaac tatatactat taacataatt tattatttat attgttcttt
    13021 ttaatctcta ttccatttag tctaggtaac attactcttt acaagattac tttatatttc
    13081 ttttatatct ctaacgtttt tatttaataa aacaattatt aatacaagtc aaatatatct
    13141 atttatctaa aaatatatct tttacagtaa tatctggatg gtgatacttc ttcctattcg
    13201 ttaaaaaaga tttttttaca ttaatagcct cttttggaca ccagtgaaaa caagctaggc
    13261 atctttcaca ctcattaccc cactttggct ttttatcaac tatacttata ttctctacag
    13321 gacaaaccct tttacatgtc ccacatccat tacatttatt ttctgcaaaa aatttagtag
    13381 ttgcaatttg catattctta cctactaaac gaagtacaac actatctata tgtgacttta
    13441 aattgttttt tccttctata tttccaatct ccaagttatt gatacatttt gcaatctcag
    13501 ctaccctatt agtctgattt ttcaatcttt cttcttcaac atctggaggt gttatcaaag
    13561 catttccagg catattgatt aaaaaaccag cagataattt tttccccctt tttttaagta
    13621 acttatctat agtaaataaa ctatgtccag ctaccccatt acaagtggca atggcatata
    13681 tatgagtatt aatattaaaa tttaatttct ctacaaaaga ctttactata tcaggaacat
    13741 cagcaaaata aacaggaaaa acaattacca atatatcttc atttatgtct atattatttt
    13801 cttttctatg tatagctaag ggtataactt ctttacttcc atttaacgtt tcttttaaaa
    13861 tatttgaaac tactagcgaa tttcctgttc cagaaaaata ataaatctta ctattcattc
    13921 ttatccctct ttctatattt ctacatcatc aatagttaaa aagtctctta aaataggatt
    13981 tatatttact ttccaattct atccaaaata tcagtaaaca aaggcaattc ttcatcagag
    14041 atagatttaa atgtctctgt tgcatatata cttgcaattt catttaatgg ttcttctaat
    14101 tctctaccta aatctgttag gaatatttga aacttacgtc tatctttaac atctacttta
    14161 cggacaatta atcccttatt tttcataaca tctaaaattc ttgttgtatt agatttatcc
    14221 ttacatgatt tttcacataa atctatctga gaaatcccat cttgctccca tagaaacctt
    14281 aataacgcat aatggtcagt tgttatatca tatccatttt gtttaaacat cttttttaaa
    14341 tcatctttta cttttaacga agtacttact aacttagttg tagcttcata tagtttctca
    14401 aaatctttca ttttacctcc atttaaataa tcccttgctc ctcccatcta tcaattattc
    14461 ccttatattg ctcaatatct ttaaaagcca ttggctttaa aacagcattt atagcaataa
    14521 aattatagat ttgagaaagc acaggtggat ttttcttttc ctctatgcaa taaataaatt
    14581 ttttagatac cttttgtatc tttgattcta ctttttcagt tataggattt tgattaaatc
    14641 cagtttttat agataaacta ccacaaacat aacctcccga atctaagacc atggatttta
    14701 taaaagaaat tgcttttgaa ccacgtgcat tttcatatgt agtaactgct atacatggct
    14761 tacgatacaa taatctttca agcatcatat gtgctctatc tgtaaacacc ttgaaaagtc
    14821 cagttacact acttccataa gttgggctac caaatataac accatcactc ttagtaatta
    14881 tatcatgaat atactctact ttatcatttt gattgataca cttgcccatt ttataacaat
    14941 ttaaacaacc aatacaatat gatggattta cctcacttaa atcaaaataa ttaattttta
    15001 catctggtat taatctttct atatctttat acaagtaagt taaaactttt gatgtagctc
    15061 cattttttct agggcttcca tttataactg taattatcat ttctatatct cctttttagt
    15121 tgttatatca acaataagta tatcaactat aattttagct gtcaatataa accatttatt
    15181 taaagctata cttacacagc ttaaataaaa gttttattta actacatgtg cttatttaat
    15241 caactataaa tgaattattt ttaataattg acaaactaaa ttaatgataa tatactttat
    15301 gtattacaaa tgtaagtaga aggaggtata gtatgaaaaa gttaccacat atttcagaag
    15361 cagaatatca agttatgaaa attatttgga aatatgctcc tatcagcact actgaagtaa
    15421 ttgaaaagtt ggtagaaaca agtacatgga gtcctaaaac aattcaaaca atgttattga
    15481 gattagttaa aaaaggagct ttaacatatg aaaaaaatag cagagtattc gtttatactc
    15541 cacttgttaa agaagaagaa tacgtagcta cagaaagtag ttctttttta aatcgttttt
    15601 ataatggtac tcttaattct atggtactaa actttttaga aaatgataaa ctatctgaag
    15661 atgatattga ggaactgaga gaaatcttaa ataaaaggac gactaagggg gataaataaa
    15721 tatgtatgcc ccattcttta tacgattttt actcagtaca ttaaccttat caatattaat
    15781 tgctgtaatt ttacttgcca aaaaagtatt taaaaaacat atttctgcaa agtaccaata
    15841 caatattgga tttatattgc ttataatgtt aataattcca tttgtccctc ttaaatatat
    15901 taatcttgga aatgtattta actatttata tacttttaat caacttggaa gcagtactaa
    15961 taggacttct atgataaaaa atagtccaaa ttctataatt aataactcaa atgcattaaa
    16021 cgatttttca gtatccctaa accaagttaa ttttgatagt ttaaatattt tattactaat
    16081 atcatggata attggaattt taatcatgat agctattact attcattgca acattaaaat
    16141 aaaaaatatg aaaaaatcaa tacaaatttt aagagatgag gagatagtat ttatatttga
    16201 aaagtgtaaa aaagatattg gtataaataa ggattttata ctatgcaaat cacctattat
    16261 aaatacacct attacatttg gatactttaa accacacatt atattaccag ataagtctat
    16321 atctaaatta tctttaaaag atataaaata tatcttactt catgaattac aacactttaa
    16381 aaataaagat atactgataa attatataat gtgcttcctt caaatattat attggtttaa
    16441 tcctcttgta tggtatgcat ttaaagaaat gcgtatagac cgtgaaattg catgtgatat
    16501 ttcagtttta aaaaagcttg ataaagatag tcatatagaa tatggacaaa ctctaataaa
    16561 ctttgtggat aatatttcaa gaccatcaaa tcttacactt acatcagata ttggtgggtc
    16621 aaaaaaacaa ataaaaaagc gactattgaa gataatggat tttcataatg aatcaaatac
    16681 gttaaaattc aaaagcattt taatttttac attgatagct ttaattgtat ttggaaatat
    16741 tcccaaacta tctattatgg cagatatcaa tgaaaaatat agacctacaa atgaacaaac
    16801 tgtgtacgag gacttaagtc agtattttaa aggttttgat ggaagttttg ttatgtatga
    16861 tttaaaatcc aagcaatatc atatttacaa taaagaaaaa agtaaaacaa gaatttctcc
    16921 aaattctact tataagattt atagtgcctt attgggattg gaaaatggga taataacaag
    16981 aaataattca catatccctt gggatggaaa gcatcattct aatagttctt ggaatgaaga
    17041 ccaagactta ttttctgcta tggaaaactc cgtaaactgg tactttcaga ctctagataa
    17101 aaaaacaggg ctaaaaaaca tacaaactta tcttaggcaa attggatatg gcaattatga
    17161 tgtttcaggt ggtatctcaa acttttggct agaatcttca ttaaaaatat cacctattga
    17221 acaggtagaa ttacttgaaa gtttttatac aaataagttt aaatttgaag ataaaaatat
    17281 agaaacagta aaagattcat tgttaatatc aaaaaaggat ggggtatcac tttttggtaa
    17341 aacaggcact gccaatataa atggaaaaga tgtaaatggt tggtttatag gttatgtgga
    17401 aaaaaatgaa aatacttatt tctttgctac aaatattcaa agcaaagatt attctaatgg
    17461 tagttcagca tctaagataa cattatccat attaaatgac aaaaaaatct ataatcctta
    17521 atatatttac tgtacattct aaaaaattca cataattttc atattaatta tcaattaaat
    17581 tcatatacaa ggcttattat ataaacatag aagatagtaa aactagctta aaaacataat
    17641 ataataccct atacaaatag tggcaactct ccctcacatc ctcaattgtt gccactattt
    17701 aattttttgt atgaagttaa atatattttc atcatttcaa caatttgggt gcaatacaat
    17761 ctctattttg aaacaacctc tttaattgtt ttagagttta tgaattattt ctcatacttt
    17821 aaaaagattg aattactctt gataatcttc ttttgtagtc attacatatc acctactact
    17881 caacacatat tctttgacct atttttacat ccttgtttat atccaaaata tttaccttct
    17941 taccatctgg aaacaatacc attgttaaag tagactttcc taattcatgt attctcttta
    18001 aatcaacatt aacaagaaca tctccctgtt taaccatatc tccttgttta acagcaatat
    18061 caaagccatc tccatttaat gcaactgtat caattccaac atgaattaat acttctccat
    18121 tagttccttt aatcccaaat gcatgtccac ttgaaaccac tgtttctaat ttacctgaaa
    18181 taggagaaac aatttttcca tctataatat caatagcaaa accatcacct aacatttttt
    18241 tagaaaatgt ttcatctggt acattttcta atgcaacaat tttcccctta gctggagaca
    18301 caaagttttc attattttca ttaaacacta attcttcgtc ttcatcttca tttatagctt
    18361 ctttaggcac tccaaataaa catgttacaa taaagcagaa tgcaaccaca aatattgatg
    18421 ctaataagta tgtgattaaa ttatatccat catagatata cattaaataa gaaggtaaaa
    18481 ctgctaatcc atatgaatta gattgaatat gtaaaattga taatattgct gctcctaaac
    18541 ctgaagatgc acacataata atcaaaggct ttaaattata tcgaagctga atcccaaata
    18601 aaacaggctc acttatacca aaaagttgag atagcattgc tccaactgca gtttgtttaa
    18661 cttgattatt tttagatttt ttcataaatg ctagacatgt tccaatattc gcaaatccat
    18721 acattgcaca aagagtaata agggcattaa atcctgtatt tgctaatagt gatgtttcaa
    18781 tcattacata agtatgatgt aagccagtaa taacagctaa tggatatgta aatccaataa
    18841 taaatcctcc aattcctaaa ggcaaatcaa tcaataagct gatgatatca accattttta
    18901 attctattgt atgcattata gggcctacac ctaacaaaat aactaacatt gttattagca
    18961 taacaaaaaa tggtgtgaaa ataaggtcta atacattagg catatgttta cggaaccatt
    19021 tttcaagatt agctccaata aatgctgtaa caatagctgt taaaacactt ccttgacaac
    19081 ctacaatagg aataaatcca aatgccataa ttgcttcaat ttcatttgat gggtcagcaa
    19141 cagaatatgc attaggaagt attggggaaa ctaacataag tccaataaca agtccaataa
    19201 caggtgttcc tccaaatact ttaaatgctg accatacaat aattgctggt aaaaaagcaa
    19261 atgctgtttc tgtaagaacc gaaacaagtg tctgaatata caatggaata tttgcagaag
    19321 acattccaaa taatccaagt acattatcat taaacaaaca accctttaat cccaagaata
    19381 atcctgttgc tgcaataact ggaataatag gaacaaatat atctgctaga gttctcataa
    19441 ctttcttaaa tccagtttca ttatttttaa ctaattcatc ttgttctttt tttgataaag
    19501 tttttaatcc cattttttca acttctgcat aaactttatt aactattcct gttcctaaaa
    19561 taatttgata ctgtccagaa gtaaagaaaa cccctttaac ctcatcaact ttttcaactt
    19621 tcttatcatt aataatttct ctatctttaa ccatcactct taatcttgtg gcacaatgtg
    19681 taatagaaat aatattatct tcaccaataa ttttaataag ctcatttgct attttattat
    19741 atttattcat ttttctacct cactttcaat aatactgcat gaaatggttt caaacgcact
    19801 gttttattta atagatttat atcatctaaa ttttggaata caatatcata tttttcttct
    19861 actcttattt ctacaggttt atcagaaaaa ttataataac aatcaataac taccaaatct
    19921 aattgccttc tatacgcaat aatatcatca ctttctatat caataggttc tattgaacca
    19981 taaatcaaac aatcagaata ctcactatct tgtctcaact ttatcatctt tttataaaat
    20041 tctaaaatac tctctgaatt gttaatctga ctctgtgcat taatatcttt ataattttca
    20101 ataaccttta accatggtgt tgtatctgaa aaacctgcat tttctttatc tgcccatgga
    20161 aatggcgttc ttgcattatc tcggcttctt aaattcacaa attctaacgc ttcttcttct
    20221 gagtaacctt catctattga acgatagtat tggtcaatgc tagataaatc attaaaatca
    20281 tttatggtat ctcttttaaa atttgtcatt cctaattcct gtccctgata aataaatggg
    20341 gttcctctta aaaagaaata cattgctccc aacattttta ctgcatcatc attcctttcg
    20401 tattgcaaaa gatactttgt tgtagctctt ggttggtcat gattttcaat aaaattagct
    20461 gcccatccat gttcctgaac atacatttga ctatctaaaa tgcattttct taaatctgga
    20521 attgtccatg aaattctttt aaaccactca ctaccagaag caacatctaa gtcagcatgt
    20581 ttaaagtcaa agaccattga aaagaaacca tcttctccaa taaaatcacc taactggtca
    20641 tagctaatac ctgctgcttc agcaacagtc atacaatcat attttttaaa cgtattttct
    20701 tttaattcat aaagcatttt ttctattcca ggctgatttc taactgtttt tgtacattta
    20761 acaagaccat caacaccatc actttctaaa ctttgaaaac ttaaattctt tttgatgaat
    20821 gtaatagcat caactctaaa tcctgccact cccatttgag accaggtatt aatcatttgg
    20881 taaagttcac ttcttaatat tggattttcc caattaaggt caggttgttt ttttccaaaa
    20941 gaatgaaaat aatattcgtc tctattctct accttttccc aaacacttcc accaaaaaca
    21001 gacctccagt tatttggcaa atcgtttcct tttttaaaaa tataataatc atgataagga
    21061 ctttctggat tttttaatgc ttcttgaaac caaggatgtt catcacttgt atgattaaga
    21121 actaaatcta atataatttt gattcctcta tctttacttt ttttaattaa ctcttttaaa
    21181 tcttccatac ttccaaattc acttgcaata tccaaataat cactaatatc atacccatta
    21241 tcatccatag gtgatttaaa aattggacat aaccacaatg atgtaatacc taaatctttt
    21301 aaataatcta aacgagaaat aattccctgt aaatctccaa ttccatcatt attactatct
    21361 tgaaagcttc ttggataaat ttgataaacg atttcttttt gccaccattt cttttccata
    21421 aattactcct ttttatatga tatttcttct ttttaattct ttataaattc cattatcgaa
    21481 tatgtcctca catatagatg tcgctatatc tttaagttgt tgatgactat ttttcattgc
    21541 aattgtaacg tctgatgctt gaaacatgac aatgtcattt tgaccatcac caaaacatat
    21601 ggtttctttt tgagttactc ctaatctttc ttgtaatctc ttaattgctt tgcccttatg
    21661 aaaatctttt tgaataattt cataatactg actagaaata tctctctgtg ctaattccat
    21721 tttatcttgt agtatatctt tcacttcgtc aaataccttt tcatttgacc ataaacaaat
    21781 tttatgtata tcttgtgact tatactcttc aatgttattt tcatatgtta ttttttcttg
    21841 gatatgttgt ttatttatac aagaattagt tcctttcaac tgattcattg tttcaaatat
    21901 ttctttggct ttttgattca tgaaaacttt ttcctgactc tcaatcgaaa aagcaacttc
    21961 tctatttttt aataaacaaa caacttcctt tatcaatctt tgattaaaag attgattata
    22021 aagtaattca ccatgatatt gaatgtaatt acctcctcct gcaatatatc catcaactcc
    22081 taatgataaa acatcatctt gtattgtacc catacttctt ccagtacaaa taacaacact
    22141 gcaatgattc ttttgacata aacgtatagc atgctttgca gattctggga ttccatatac
    22201 ctcatctcta agcgtaccat ctatatcaag tattaataat ttgtacaatt tcatcttcct
    22261 ttcttactat caaaatcata atagcattca aaaaaaaaga tatcaatatt ttgatatctt
    22321 ttaaaaaata tgttcatttt tagcacaaat tttcattttc ggggaatatg ttcactttct
    22381 aaatacatct tgtatttaat ataaagcagt tcaattaaaa taaaataagg tgttgttaca
    22441 tcgtagtcca gttgtttatc tacagaaata gatatagatt gaatatacag gttttcatca
    22501 cataatcttg ctaaaggatt acttatcatt tttgtaatag aaaccatata aattcctttc
    22561 attctcattt ctttagcaaa atcaataatt gtagatgcat ctccattcaa tgaaataaag
    22621 aaaatcatat catctgtttt tataaaatga ttaagtgcct gaatcatatc ataaccataa
    22681 acatcatata taattttccc tgttggtaag aaaatccttt tcatctcttt agcaactctt
    22741 tcctgagaat aaccttctcc aaagacgatt atacgatttg cctttttcat tctttcaaac
    22801 ataatcgaac aatccttctt ctctatatca tttatcacct tattatagca atccattaat
    22861 tggtgtttac tttgattttt atattctact tctgtttcat ttaagcgtat aataactctt
    22921 aattcactat atccaggtaa ttgtagtttt tgagcaaaac gagaaagtgc acttgtagat
    22981 atatggtatt tgtctgcaaa ttcatctata gaaagtttaa tacaatcttc tttatgatta
    23041 agaatacact cacagatata cttatcattt gctgtaaatg aattataata tttattgaaa
    23101 agtccttcaa ttttcattct tttctccttc tatactctat gtaattcata tgaagcaaat
    23161 ctaatagagc ataaaatgct cctacgactt cataagatat agcttgtaat gtatcaagtt
    23221 tttgagtttc aacatacaga ttatactcac aaagtgttgc aattgtatta ttatcaagcc
    23281 tagttaaaga aatcgtatgt atatgattgt tgataaattt tgcaatttca attcctgctt
    23341 ttgtttctcc agacaaagaa atgataataa ataaatcact tttttgaaat gattctctca
    23401 taaattcaat ttcacctata tcaaataagt caataacaca tttacctact gaaagaaata
    23461 ttctctttat ttcttgagct aaacttttct gttcattacc tgtcccataa atataaattg
    23521 tttctgcatc atatattatt ttacaaatat cttgaaatga tattttttgt aattcattca
    23581 ttaatagtcg ataattctcg caaacatcat gaaaattatt atcattatta acaaattcta
    23641 gttgattatt tttaagtaaa tactttaaat cagagaatga atctaatcca atttttctac
    23701 aaagccttaa taaagtagct ctagaaacat tacattcatt tgcaattttt tcacacgaaa
    23761 aattacggta ttctctttga caaatcaata tttgtttaat aataatttta tcattttcat
    23821 ttaaattatc ataattttgg ttaactaacg attctaatct cattttttcc actccctaaa
    23881 tattatttta atatacatta gttgcttttt ctagggaaga gttttaaata ataaggataa
    23941 aataatcatt tgattttatt tttattaaaa taaaaataac ctgctaaaag caggcaccaa
    24001 aaagtactta tcctttcgaa catgtacttt agatattgct ttcttcggaa gcttcatctc
    24061 ttcatactct aaaatagagt tttttctaac tcaaaagtat tttccatggt agaaattact
    24121 ttaattcatc tgccatttat tttttatctt atttaataat tactactact tgaatattta
    24181 cttctttaag taaatttcat agttaacaaa gctaaaatta ttattataga tgttaaaata
    24241 caaaattgta agtattgtta taaatatgct tacagctaca aatatacatg atatattaaa
    24301 aagaagctgt aaattattat catacataca agcaactacg cctctattaa tccatgttaa
    24361 tttttattat ttaatacaag gagttccatg agacatacat atccattcat attttaaatt
    24421 atccaattct cttatagatt tcatcatctt tttataatcc caattccatg gattaggata
    24481 aggaactata tttccattct tatttttgac taaatcacct gcaaataata catcttcaaa
    24541 aatcatgcag acatgccctg gagtatgacc aggagtatgg ataattttta tattcccaat
    24601 ctgcatattc tctccataag gttcaacatc cttaatgagc cttctggaaa ttgcctttcc
    24661 aataaacttc ttaaacccag gtctatcctt ctctcctata ataaaaggta tatcctctac
    24721 atgagcccat acttttgctc ctgttttttc tttcaataat ttaatattag atatatggtc
    24781 aacatcatga tgagttaata aaatatgctt aatatctgta agtttaatgc caagtgtttt
    24841 taattcttta attatatttt tccccataaa aggaagacct gtgtctataa gaataatttc
    24901 tttatcaaac acaataaaac aatttgagcc acgagtacta tctaacatta atacattttc
    24961 ttttatcttc ataaataaat tccccttatt tggtatttta cctatataat taattaataa
    25021 agttataaat agttataata cttgatatta attttatttt ttattaaagt atactatagg
    25081 tatacaaata ttatatttac ataaatatac catcagtata cttttttatc aatagaaagg
    25141 aataatttat atgtcagaat tatcaaaaag agataaagaa aaaatacaaa gagaaaatga
    25201 gattattgat aaggcagaaa aattattttg tcttaatgga tttgataata caactatgaa
    25261 tgaattagca aaagaagttg aatatactaa acgcaccata tacaagtact tttcatgtaa
    25321 agaagattta ttctttgctg ttgtcttaag aggatataaa agactttggg ataatgttaa
    25381 aatagaaagt gcaaaaggca aaacagggtt tgaaaaaata aaactttcat actttgcttt
    25441 tcataaattt tactctgtag aaccttctct attatgcctt atgggaatga ttggtattgt
    25501 aaactctgaa aaatcggata ctgatatgct gtttaaagaa aagttttttt cttttaataa
    25561 atttatgttt gatgaaatac aaggaatgtt tgaaattgga aaaaatgata gaagtattag
    25621 gcatgatatt gaaataccta ctcttatgta ttcatcaata tttacactta caggattttt
    25681 taatttacta tctgtaacag gaaaatcata cctgaacaac tttaatatag atgaggaaaa
    25741 atttattgaa acaactcttg ctcttttaat agattcaatt aaagcataaa cctaagttta
    25801 taaattaaag tttatatact taaatgataa ttttttctat ctctaatatg aaaaatatta
    25861 aacataaaac taataactta gttaatggaa taactaaatt actgaaagga ttaaaagtaa
    25921 atggctaaaa tacttctttt agaagataat gatacaatta catttggaat aaaaacttcc
    25981 cttgaaaaga aaaatcacac tgtatgttgt tataatacga ttgctgaagc taaaaaaaat
    26041 tttgataaaa ctattgattt aattctgctt gatttaaatc tacctgatgg tattggatac
    26101 gagttttgcc aatatgttaa aagtatagaa gatactccag tgatattttt gacagtccgt
    26161 gatgatgaaa aagacattat acgtggatta gatatgggtg cagatgacta tgtggttaaa
    26221 ccgtttttgc tctcagtact tcaatccaga attaatgcag ttcttagaag aactcattca
    26281 aatactaaca atactattac atgtgaaaat ataagcttga ataaggttga agtcaaagca
    26341 tatttagata atgttgaagt acctttgaca gcaggagaat ataaacttct tctaagtctt
    26401 atggaaaata aaaatagagc tatgactcgt acaaagttac tagaaatgct ctgggatgta
    26461 gatggtaatt tcgtaaatga taacactctt actgttacaa taaaacgtct tagagaaaaa
    26521 ttaaaaaatc caccttgtat aaaaacatta agaggcatag gatatagaat ggaggacaac
    26581 tagtgaaaac tccaagaaat atcaacagta cagttgtttt tataatattc tgcttaattg
    26641 taactttttt attgagtgta attctaacaa ctataacttc ttttaatgaa tacaatgtac
    26701 tgtctaaggc tcttggtgca tcatatgagt acaatcctaa gtctacagaa agtatactaa
    26761 aatcactgaa aaattctagt gataaggatt ttaaaacagg aaatgaaatt ttatcaaaac
    26821 atggatattc taaaagtaca ttttggagta aaaacttttt ttattttcta gtgatatcgt
    26881 ttggtataat ttcaacaatg gctacagttg tatatataat caaacataga acaaataagc
    26941 aaaaactgag tagaataaac aatcttactc aatacttaga agaagtgaat ttaggaaaag
    27001 agtctgtact tttacgatgt gaagatgaat tttctcacct tgaagatgag atatataaaa
    27061 cagttgggga acttcgttgt tcaaaagaat ttgctttaaa agaaagacaa actctttcag
    27121 ataaccttgc agatattgct catcaactta agactccaat tacctctatg tcacttatgg
    27181 cacaattact ttcagaaaat tgtccagatg aagaaataga ttatattaac agacttacaa
    27241 atcaaatctc aagacttgag agactagttt catctttact tacattatca aaattggatg
    27301 caagtacttt aatatttgaa agcaaactta tagatgtaca ttctcttctt acttatgcaa
    27361 ttgagcctat agaaggttct ttaagagaaa aacatcagac atttactatc gaggcttctc
    27421 cttcggtaga atttgaaatc gatattaatt ggactttaga agctctttta aatattctta
    27481 aaaattgtag tgagcatata gaagatggtg gatatatagt tgcttattat agtcaaaatc
    27541 ctctatatgt tgagattatc atagaagata atggtaaggg gtttgctcag gaagaacttc
    27601 catatatttt taatagattt tatcgtggta aaaatgctag taaggacagt attggtatag
    27661 ggcttgctct atcaaagtct attatagaac gtcaaaatgg tactctacat gcagaaaatt
    27721 gccataatgg tggtgcaaga ttcataatta aattttacac ataaaatgct ggattatagg
    27781 taaaatacct ataatccagc tatatctata ttctatgtta tctattgttt tagtaatata
    27841 cttctattta catttaaggt tttattaaac aaacaactta actatcccta tacttgtaag
    27901 tagtcttaaa tcgaaacctt taaataagtt caaatagatt ttgtttatat tgtttcattt
    27961 tttatagatt ctactatatt ttcattcttc aactgcttgt atcctgtcat atatgatgct
    28021 attacaataa aaagtatcaa tatagtaaaa cctattattg tagatatagg tgcaaatggt
    28081 aaatactcta taaaatatat ttcatttata cgtagaaaag catacactat tcctatttgc
    28141 acaggaatac taagtagtaa tggtgtaatt cctaagaata aaccttccaa aataagcatc
    28201 ttttttatgc cttctggaga taatccaaca gaacgcaaca tagcaaactc ttgtcgtcta
    28261 cttctaatat ttcctgacac tgtagcaagt acatttgata atccaatcat agccaataaa
    28321 cctgtaataa agcctactat taaattcatg gtctttattc cactagcctt ttgtttttca
    28381 ctttctaaaa catcctcaat actataatct cctgaaccat agtctttatt ataaatggac
    28441 tctaattttt ctcttactct aggaatgtcc tcacgattat ttactttaaa tactcctatc
    28501 agcctatttg aacgtaacct acttacttca tcataatttt tagatatttc ctgcaccata
    28561 gacattggaa ctatttgcat taatgtatac tttgaactag tatctactat tttaggaagt
    28621 gtgcttgtaa tagctcccac tttcatgttg taagtataat cccctttatc ttcgtcatat
    28681 actttttcat ttaatttaat gttatctcct attgaaagat ttaaataatc tatatatact
    28741 ttatttctac gtgtactacg attaatatct tcctccttat tatatacaat tgaggttgga
    28801 ttttttgtat cataaaataa ctttgggtct acagaaattt gcctacaata ttctgtaaaa
    28861 ctcttatcat caagcccaat tatatttgaa attatacgaa acttgccatc acgttctata
    28921 ggagagtact ttttagatga agctatattt ttaaatcctc catttttcgc aagttctttt
    28981 gaagcatctt tttcagtcaa ccaagtggaa gcagacattt tttgataata tagtgaactt
    29041 tttacacctt ctgtattatc taatttttca atgaaagcag actctacagg ttcactattt
    29101 tccaaataaa ctgctatatc tctttggtcc ttataattat cacttccata aacagctttt
    29161 gctccttctt gatttgcaat tatatgcaaa aaacatgtaa gtaataaaaa agataatgtt
    29221 aaagatattg ttgcagtacg ataagatttt ttacgagcac gtagtgcgtt tgatgcaagt
    29281 tctccttcta ttccaaatat ctttcctaat gaatatttat gcgacttttt gattttaaca
    29341 ctatctcctt gtcgtattgc ttctatagga gatatctttg atacttttcg tgctggtata
    29401 agtgcagaaa tccagactgt tactattgta agtaaaactg ctggcagaaa agcaggaata
    29461 ccataagtaa ataccacttc tggaacatca gtatgataat taactgaatt aacataaact
    29521 ataagcctat tacacaataa ccatcctaaa aataaaccta ttggtaatgg tataattgtc
    29581 agtaaaaagc cttcaaacac tacagacctt ttaatttgtt ttggtgatgc accaacacta
    29641 gataatatcc ctaattgagt aagtctagca tttgcagaca gtgaaaacgc gttgtaaatc
    29701 accattacaa acacggctac tgtaaaaatt gctattgtaa gatacataat aggagttgaa
    29761 aattttgata tactactcat agatgctttc tgttctggtg aaaagactaa catctttaaa
    29821 agataattac tattgtattt aagattgtat tttccatatt cattagtctt ccatcccaat
    29881 gatttagcaa gttttggaag ttccttatac gtgtctctta tatttttaaa tcgcaagtac
    29941 acagttatac tatcattagg ttttatactt gttttatcaa gatatccaag agctgtatat
    30001 gcaggtatta ctgatgaagt agaaacatct acctttccta ctattgtcaa tgtagcctct
    30061 gaaatttttt taaaactttc ccctttcgat tttggggcta tgggttcaag aggctttcca
    30121 tttaggattc tatctcctat tgggagagta attttatcac caatttttac acttggatta
    30181 ttctcaaaat attgttttga taatgcaatt tcattagcat tatttggtcg acgaccctct
    30241 attatagtat ccttttctgg catagaattc caatactctg atgtagcatt tctataaatt
    30301 atataatctc ttttctcatc attaattttg cctacatacc attgtccttt taccattaca
    30361 tcatcaactg aagaaaaatt ttcaattaat ggtaagtcac ttccataagt atagtcaaac
    30421 aattcaccat gccagttacc ttctttctca attgaaagtt ttataaaatc tgtccacatg
    30481 gtatacaaca gtccacacaa agaagacatc atggttgtag taagtaatat agctaacatt
    30541 atagctatac tactacgttt attgcgtcgt acaaagtcta aggtgtattc ttgaagaata
    30601 ttcatttctt caccaccttt tcagagacaa tcactccatc ttccatagtt acaatacgat
    30661 ttgcctctag tgctattttc tcatcatgag taataagaag tattgtctga ttaaatcgtt
    30721 tatttgataa gtttaacaag tctacaattt cttctgaatt ttttctatca agattaccag
    30781 ttggctcatc tgctaataaa atagctggtc tatagattaa acttctagct atagataccc
    30841 tttgttgttg tccacctgaa agttgacttg gaagatggtt taatctatca gataatccca
    30901 atatagatac aatctcagag aatctatcct catccacctt tcttttatca agtaacatgg
    30961 gtaataatat attttttcta acatcaaggg taggtataag attataaaat tgataaataa
    31021 gacctacttt tctacgtcta aaaactgcaa gagcttcttc ctttaaactt gatatttctg
    31081 tatcttcaac ataaatcttt ccagatgtag gtctatctac tcccccaagc agatgtaaca
    31141 atgtagattt gccagaacca gatgctccta caatggatac aaaatcacct ttttgaactg
    31201 ataaatttac attattaagg gctgtcactc tggtttgatt tgaaccatat atttttgtga
    31261 gattttcaca ttttaatatt tccatataca atcatctcct ttatggttaa attttagcaa
    31321 cctaaaatga cattatagtg acatgaatac aaatataaat tactattaaa aatattgttt
    31381 agtttttgca cattatttaa aattataata taaaacaaaa actatgcaat atattttatt
    31441 tatactttta atatattaca tagtctttaa aaggtattaa ctttaaatct ataggtattc
    31501 aatttaataa tcaatagcaa gtattttatg tactaaagga gttttgctct atatagactc
    31561 aatttagtaa aattatttaa taaatattac agactatagg taaataatat ttacaaataa
    31621 aattaagttt attcccttac actataatat ttcttaatta tattaattgc aatttccttt
    31681 acctttggcc ctgtaatttc tttattggaa tcatctgatt taatagcaaa ataataggtg
    31741 tcaccttcac gctctagcat accaacaaac catgcatcca cacgtttatt tttttcatca
    31801 aatcctgttc cagtttttcc atatacattt atgtttttat catttacatc tattttcata
    31861 atatctctta aaatattaat atgctctttt ttaaagtttg tatctccctc aaatattttt
    31921 gccattgttt gcacttgttc ttttggagat atttgtaatg aagattctaa ccaaaatcca
    31981 tttaaatgtc cctttccatt ttttaaatct ccttcccatt cgctaatatc gcaattccca
    32041 tactttaaat catctaaaat gttttggaca gatttagcat caactttatc tatcaatttt
    32101 ttgtagtacc aaacacaaga ctccttaaat gcctcttcta aactaagatt tttattccaa
    32161 tttttatttg gatactctgt accatcatat cccataactg attcttttga gtttattacc
    32221 cctttttcta aaccaattaa agttgaaact attttaaaag tagaacatgg tgaccttctt
    32281 gtttcaatta attctttgtt atatatatta tattctttat ttttagtatt ataaaaaata
    32341 gctcctccac taataccttc aaaacaatca ctatagtcaa ccatattaat tttttctttt
    32401 ttgtttttat tattgttttc aattttggat ttatttaatt cagacttatt taattcagat
    32461 tttatataat tcttatcagt tttttgattt atatcgttat gttttttccc tacataatac
    32521 attaccataa ctacaccaac caataagata gctatccaaa taaaattctt ttttcttttc
    32581 ataatttata tcatctccca tatttaaatt tataacctac tattaaaata gtagacatta
    32641 tttgtaatat actccaatct aggttctact tataagaaac aagactaaat gaatagctgt
    32701 atctcttata ttttcttcac ctagtacaat tatgttgatt aaacctattg cgaagataat
    32761 taagtaacta ttaataacat cctgtcctcc ttttaatttg tgatataata attgattcca
    32821 catttaaaac ttactattgt aatatttaaa tattacaata gtaagtttta aatgtcaagt
    32881 tagtttggga aagttatttt aattgtataa ttgttattac atttataaaa tatggcatgt
    32941 ttaaaattat tttgctattg ggaggattaa gataagcagt attataaaag ctataaatta
    33001 taaaatttaa tatataattt atagctttta cttttacaaa tattgttttt attgatttat
    33061 taatgaattt tattgacagg ttatatttat ataagtaaac acttacataa taagtatata
    33121 atctacatat ctataagttg agtcaattca ccagtatatg tcaacttaag tttatgcata
    33181 gctcgtgtac aagcaatata taacaaactg cggtcataat cactataata tgttttatta
    33241 tttactgaag gtacaataac ttcatcaaac tctaaacctt ttgacatttt aatagaagtt
    33301 atggatactc cttttgtaaa gctagaactt tcagaagata ttaagtgaac actatatttt
    33361 tctcttaacg catcatatac agctttagcg tcattatctg tctttaatat aataccaaga
    33421 gtcgcattat cactcttttt aaattcttca atttctattt ttatcttatt tatttcatct
    33481 tgctcgttat tacattttaa taaagctggt tcttcaccat gtcgttcaat aggctctaat
    33541 gaagatatgt cttgaatctt tttggcgaaa ttaataatct caaaagtaga acggtaactc
    33601 ttattcaaca taactagttc cccatcatta tatagctgtt tcatatcatc tagtgtatga
    33661 gtgtgattag gattaaccaa ttgtccaaaa tctccaagaa tagtcttttt acacttaaaa
    33721 agtaagttta ttacagcata ttgaataggt gtgtaatcct gcatttcatc aataacaaca
    33781 tgtcttataa tcttatcttc ttgtatacct tcatatgcag catgaatata tataaatggg
    33841 tatacatctg accattcaag agtttttttt gttgccatca caaacatgtt tgatatattc
    33901 atttgtttaa agaaatcctt atatagtgta agagtatttt ttattgtcaa cattccattc
    33961 aaacttttaa gtatactttt tacctttggt aaatcttctt ccataatatt atctgattca
    34021 aatttataat gaatgtcttc agctaccttc tctaatctct tcttaactgg atatctgtta
    34081 tatgcctcaa atctactctg tatccagtca cttttagctg taaaacttcc aaaagtgtag
    34141 tcttttggaa taaaaatctt atttggcatt tgttttatat aatcatcaat aagttttaca
    34201 aaatcaagtg tagatttaaa acgcactctt tcagaccatt tagcatcatt tatttctaat
    34261 gggtctttct cactttcaaa attaataact ctatctaatt gtacctctgc tatattttca
    34321 aaacttaatt cacataatgg ctcttctcca agctcaggaa ggacattgga aatatagtct
    34381 ccaaagactt tattaggtga taggataatt acattatttg ctgatatttt atctttaaat
    34441 cgataaagaa gaaaagcaat tctgtgtaat gctatagatg ttttcccaga accagctacc
    34501 ccttgaataa tcagtgtatc agctttatca tttctaataa tttgattttg ttccttttgt
    34561 attgttgaaa tgattgactt cattttttca tctgaagtgt gactaagttc tttttgaaga
    34621 atatcatctt gtatattaat ggaactttct agtgcatatt ctaattttcc atttttaatt
    34681 ttaaattgtc gttttcttgt tatttctcca tccacccatc ctattggagc atcatatcca
    34741 gcttttccga tttcataatc ataaaacata ctggcaattg gagaacgcca gtcaagtatt
    34801 ataagctcat cttcataatc aaatgcaaat ctaccaatat aatacttaga ttcatcatcc
    34861 atatctttca gcctaaaatc tattctagca aagtatggag aatctttgat tttattaatc
    34921 ttatctcgaa cttttaccat aaaagcccca tagttatcta tttgttttag tccttgttca
    34981 ttttgaaaca tttcatgtgg gtctatttca ccacgatttt ttaccatata cattttagcg
    35041 tccatataat ccttatcaag cttgtcaaca agattttcag ctttcttaaa agcattgtct
    35101 agcttgttat ttatctctat tagatgtgca atctcatctg gaaaaaaagt taataactct
    35161 gcatcatatt cacacatatt atgtttagaa ttagatgcaa taatatcgca atttactact
    35221 tgtttatttt cagacattta aatcctcctt tgttaattaa gtacttacac tgaatcatta
    35281 tacttaattg tgttttggag tttttaatca ttcttgctat ttaacttaaa tgttagcttt
    35341 ttagctttaa agttcctttt ttaaaaaact aaatctttct atatttatta ccataagtac
    35401 acttacaagc aaaatacatt aaaagcagaa atgctcttat atataaaata attcaaacaa
    35461 aaaatatgtg gtaaactttt catttaatct acaattaatt ttgtctatta tctctttctt
    35521 ctacacaagg aagaataaat ttttgagtag gatatccaaa ttccacaagc aattctgctt
    35581 ctgcaaagcc caacttcttt atcatatctc tatgtcctgt atcagctttg tcaccctctc
    35641 gaaaggtagt aattgaaata tctgtatcta tcaagaaatc ttcaataact ttcttcaaaa
    35701 acacttgtgc aatgtctgaa ttacgatact gtggatgtat tccaaaaaaa tcaatacttc
    35761 tagtttctct attaaacacc atatttgcaa tagcgacatt attaagtttt aatattaaag
    35821 ctctttcttc taaaatatac tgttctaatt gatatatata ttcttcctct tgcaaatttg
    35881 gaaatccatc tatgactaat ctcactaaat tcatccataa tggtatgtca gacatacttg
    35941 caagtttaat ttctttttcc aactctagta cattctttga aaataggtta tcttttttca
    36001 aaacaaatct tagctgcaaa ggataaaatt cttgttcttt cctatattta tttggagatt
    36061 ttttatacat agctttaaat atagaagtga atgcctgttg actttcatat ccagctatca
    36121 atgcaatttc aataattggt ttctttgaaa ataccaataa ttttgctgct tctgtcaact
    36181 ttctccgctt tatgtaatca tgcattgtta gaccaacaga agttgtgaaa gttctatgca
    36241 ggtgatattt tgagtaatga acagcattag caactatatc taaatccagc ttttctgata
    36301 aatgctcctc tatatagtca atagcagtta tgacattaat tactttgtaa gacattgcag
    36361 cttccctcct tttatccatg caacattata tcaattatta cttagttata tttaatgaat
    36421 cttgctattt tataaacaaa tttgttgttt aagttttcaa ttcataaatt taatatatta
    36481 ctttttactt tctgattaaa gactctaatc ctttaatttt caataacttt tcatttagta
    36541 aatctaaaaa gttatttatt attttcttct tattagattc cttttatatt ccttaattaa
    36601 atgataaata tttatattat acgactaaaa acagcttttt acaattattt aatatgatta
    36661 caaacttacc ctatcttaaa gtttaatggg gtcctgttat gaatcttttt attttaattt
    36721 aagctcttca tcagtttatt ttatatattg atgtatttga tttcatacaa aaaagagtgc
    36781 ttcatgaact aaaaagttca tttttaaaca ctctctttta tgtaaataaa tttctattct
    36841 attttgaaat attataattt gacttataat ctgttaatac caaaaataat aaattgtacg
    36901 tctaagaata gattctaatt agttgctcag tagtaaaatc tgtttttaac taatcctgct
    36961 ttgtatgttg aacatattct ataattgtac catctggatg tctcaatgtc atattatatc
    37021 ctgtaggaac ttttttctta tctcttacta caactgctcc attatccaat agataacttc
    37081 tccattcatc aacagaatca accataaaag tagattttgt ttctataaat ggtttaagag
    37141 catcatcaga accagataat agtaaaacat ttcctatttg cgctaattcc aacccaactt
    37201 ctttatagga aaaacgcaaa gaacattttt cttttaaaag attttcataa aaaggtatgg
    37261 ctttttctat atcttgaata taaaaacgtg ttaatatatc atatattttc atattttccc
    37321 cctatatatc tatataatat tacctctaaa ttataccact ctacaaatta tataacaata
    37381 aattaagcat agccttttga gcatcttaag tagaccttaa caatatattg gggttacatt
    37441 agaatacata aattaaatca ccttgatatt atttaggata aaatttatgt agtagcagta
    37501 aatgttcttc taattatcaa ctaacaaacg ataatcttta actttctata taatgggtaa
    37561 catcattttc gtaagatatt cactagctgg acgattgata tcatttaaat actggtaata
    37621 tatatcgcca tgaagtttat atccattgct atttgcccat gaaaataagt cttctaaagt
    37681 agggtcttgt aattcataag gtcctaaatc aattgcagtt attattttct gtgcaggaac
    37741 aatcctttgt agaatctcat ttttcccatc tatataagtg gctacaggaa accctacttc
    37801 aacatccaat tttgctaaat ccatgttatg aaaacataca atcggtgctc ctgaagataa
    37861 aattcctctc tcctccagat atttagaaat tttttcaaaa ctttgttttg aaaactctga
    37921 aaactctacc ataaagtcaa ttgtttttcg tattgccaaa aaacagtact cagattgttc
    37981 agctattgtt atattggata ttctagtcat tttattcctc cattacttta ttttcatttc
    38041 taatcttttt ataccaaatt atacgaaaat ttactgtgta actaattatt tcatatgaat
    38101 ataaaacata acctccttcc atttcttata tcgaaagtat agcaaaaata atctcatcat
    38161 tcttgtcaca cagtgctctt ataatcagaa catacttaaa agacttgcct aatttttagg
    38221 caagtctaaa agaaatcttt ttctataaaa aatttataca aacaattaaa agatcaaaat
    38281 atagactaat ataaaactat aaatttacta atctgaacct cccatggcta aagtcacaag
    38341 attactgatt tatagaattt cgcacactaa aatatgtctt actaattccc cacaggctac
    38401 ccccctagtt cctacgttct tacataagtt atctattatc aaacatcaaa atttaaacaa
    38461 gtttcaggtt catcttctat tcttgctatt ttaaacttac atgcaattaa tactaaagat
    38521 actattggat ttataatatt taataaagcg tatggaccat atgttagtgc agatacacct
    38581 aatgttgctg ttatatacgc cccgcatgta ttccatggta ctaatggaga ggttaaagtt
    38641 ccactatctt ctaaagctct cgacaacatc ttaggatgta tacctctctt tttatattcc
    38701 ttattataca ttcttcctgg tataactata gatagatatt gttcacctgc tattatattg
    38761 gtaattgtac aagttaccat agtacataat actgttccaa atacaccctt tgctaatctt
    38821 agtaaagaag atgctactac ttcaagcata cctgtttttt ctaaaatacc tccaagagat
    38881 aaagcgcata ttgttaagga tacagtggac atcatattca taatcccacc tttagataat
    38941 aaagcatcta cctcctgtat ttgtgttgac gaaacatatc cattttgtgc tgcatctaat
    39001 atcgtattca tagattctcc ttgaaaaact actgcaaaca atactcccaa tacagcacct
    39061 actataagcc ctggtatagc aggaacttta aatacaacca atccaattac tattgctgga
    39121 gctaataata atactggtga taaagtatta aatgtagaat ctaatgtaga cctaattaat
    39181 tctatttgtt ttatatctag tgcttgacct gaatacttca ttccaattac accataaatt
    39241 actaaacaaa ttaataatga tggtatagtc gaatatagca tatattttat atgtgtaaac
    39301 aaatctgttc ctgccattgc tggagctaag ttagtcgttt cagataaagg tgatagttta
    39361 tctccaaagt aagctccaga tattatagaa cctacgatta atccaattgg catacctaaa
    39421 ctttgaccaa tgcctaaaag agctactcct actgtaccca ttgtgctcca agatgaacct
    39481 gtcgcaagag atactattgc acagactaat gttgatgcta ctaaaaaaat atttggtgat
    39541 aaaattttta gtccccagta aatcatacat ggaactactc cacttactat ccaagttcct
    39601 ataagtacgc ctattataat tatgattaag attgcttgca ttgccatctt tatactatta
    39661 aacatactta attctaactc tttccattta aatccaagtc tatatacagc cacaagtcct
    39721 gctactgctg ctgctcctat tagtggtaca tgaggtgatg aaccatacac taatactcct
    39781 agacttaaaa ataatatcaa acaagtaatt ggtatcattg catcaaacag acttgctttt
    39841 ctacattctc gctctttcat aaaatagttt cctcctaatt atttaaacac tacactataa
    39901 ttttttttga aacatatttg ctcgtactag atgacatgat acccccataa gttaataaaa
    39961 attctaaatt gtcacctaat ttataatcat attttgtgtt acttacatct agtatcatgt
    40021 ggtctgaact tgcccctaat atttttatat cagtgtctat tggaattaaa gagtcaatat
    40081 ttatatcttg tttacctata gctatgattg ccctttttaa gattccctta tcttcataaa
    40141 caggtttatt tctaaaggca tcaactccta tttctccaat aggaactgat ggtttttctt
    40201 tacattcaac tacttggcat attaatttaa atgcatcttg atatgttcca tttatatttt
    40261 caccgtatgc cgtttctcta ccaagtagaa tggactcgcc tattctcaaa ttagtaatac
    40321 cttctggcat attattattt atcaacagat gaatagaact tgaattacct ccagatacta
    40381 tttctagatt tattccaaat ttttcttcca ttctttttgc tatacttacc agtctgccta
    40441 tattttccct agatggtata atagctccat aacaggttaa gtttgtagct ataccaatta
    40501 tttcaatatt ttttaatctt actatctctc ttacattact aaaaaagtct tcttcataaa
    40561 agtatccttc tcgtaaatcg cctaagtcaa acataagaac tatcttatga ataatatttt
    40621 tactttcaca taattcattt aatttcttta ttgttcctaa ttctgagtta aaactaatat
    40681 cgcaataatt gataacttct tctaattcac ttaacattgg gattctaatc aatatcttag
    40741 gtagatttat atcttgtaaa ttttttaagt tttgtattct tgaatctgct atatggtcta
    40801 ttccttcact acatatttct tctactattt ctttttgtgc acaaaatgat ttagtaacaa
    40861 aagatatctt aatatttctt tcatgacaca tctgcgaaat taattttgca ttatgcttta
    40921 acttttctat atctatttct aacctaggat acataatctt tcctcctcaa aattcaaact
    40981 ttttaacagg agcttaagag atgcttcttc atatttttta gataaaacac ccatagatgc
    41041 cataatatag tcattatcta ttaatatctt tgttttttcc tttggaaata gtaattcatt
    41101 atttttattg tatttgagca tattatctaa tatttcaatt ctactaggga gcctagtaag
    41161 tgctccccct gtaccaacta tatatcttac ttctgttaaa tctttccctt ctgcaatttt
    41221 gacttttcca gttgttccat agatatttct tatttttcct gaatgtctta gcatagcttt
    41281 aacaacagct tcttttgtca acctctcaac aaataatatt tcttcttttg attttggtat
    41341 tggaggataa ttctctatta ctgcatcaat atctatagat agttcacttt gtaagttttc
    41401 tttacctata acttctacta tattcttcat atttacatat acacctaaat ccccctcaac
    41461 acttctcttt gcagtaggtt caggattaac caaaatttta ttaatatagt cacttccatc
    41521 tgtaacagaa tgtacatcag tagttgctcc acctacatcc agagttaata aatctccaat
    41581 atttttatat aaaagtttag aagcttccat tacagctcct ggggttggag taatattttc
    41641 attaaccatt tctttaatgt atttcattcc tggtgctgta gttatgtgtt cttcaaatac
    41701 actttgaatg attcttcttg taggttctat attcaataaa tctattttag ggtatacatt
    41761 ttcagttata taaagcttat aattagtatc ttcaaatatt aaccttattt cctcttgatt
    41821 ttcaacatta ccagcatata taactggtat gcctagattc atagaagcta tcatttctgc
    41881 attataaata gctgtatctc tttctccata atcgactcca ccagctatta aaattatgtt
    41941 tgggtttatt tcttttattt tatttaaatc agttctttta attctacctg atgttatttg
    42001 acgaataaca gctccagccc ctaaagctgc ttctttagct gcttttactg tcatatcata
    42061 gactaatcca tgaacagtca tttttaatcc accagctgca ctagaagttg caaacatatc
    42121 attatactct atatcatcta cagataattt attagctaaa tctttaatag cacctgataa
    42181 gccatttctt acatcgccac cttcaaacac tgttgttgga gcttgacctt gacccaaaaa
    42241 tataggattg ttagtattaa tatcgtggaa agcatttacc actgtagtag tacttccaat
    42301 ttcagctacc aacacatcta tttttaaaga aaccttgcta ttttccatta tttattactc
    42361 atttctcttc ttttttcaac taagaaagtg gctacatgta tgcctttact gtttcttcca
    42421 aatccagcat ctatgccttg ttcaacagct atttcaggtg ttacttgtgt tcctccacac
    42481 gcaatcatta ctttatctct tatacctttt tctacacaat aatcgtgtaa ttttttcatg
    42541 tttttatagt gaatatcatc atgacttatt attgtagatg caagtattgc atctgcattc
    42601 agttcaatcg ctgcatctac caatttttct acaggtacag aagtccctag atagtggcat
    42661 tctatgccat atttttcaat acctccatgt tttatatcta ttatttctct taaaccaact
    42721 gaatgttcat cttctccaac cgtagctgaa actattttca taggtttttc ttctatatct
    42781 gctcttattt cttcatcagt tagtacctta ggttcttctg gtattactaa attgtttaaa
    42841 tctatatcaa acggaactct tcctttcact tctattctag tcccttcaga ttcatgcata
    42901 acttctctac ttatgacctc aatttcttgt aagttcattt ttttgacaaa ttccaaagct
    42961 gcaaactctg ctgttctttt atcagtagga agcatcattg ttatcattac aattccatct
    43021 gcacaccatt ccatttcagg cttaatttta gttccatttc tgtactcata tgattctttt
    43081 agtctatttt ctacattatc aaaatcgtca agctcatcaa tatatattat tttgtctgga
    43141 ttttcaaatg tacatccatc tattaacatt gatggattat ctatagcatt ttcatcatat
    43201 tgagctacat tattgtatcc aaagtgagca gttacaggtg ctaaataatc ttcttctctt
    43261 tcataaacag taccttcacc aactccacct tttatttttc tagatattcc atcaccattt
    43321 ctttctggat aatttccaga atcaacaaaa aatccttgtt ccacagattc aaaatatcca
    43381 ccaacttcag atatttcttc catatataat acagctcttt ctttaagttc tcttgctttg
    43441 tctcttaatt cacccacatc tttaagttct atcatatcca taagcccatc cataccaact
    43501 aaagcttgct ttgctgtatc acatgcttct atattgtata tatgccaagg tacatttcta
    43561 ccttcatcag gtgttatagt tgattgtatg tcagctctag ttaatactga tgttaataag
    43621 tttaatacat gagtaactgt tgcttctcta gttgatgatt ccatatattt agtattcatt
    43681 tgagctctca tcttataatc actaaataac tctctaagtg caacagcgta aggtaagtct
    43741 atttttaaac atggtgctgg aggtgctgtt ggtggaactg ttgataagca tatattactt
    43801 ttatctatac ctattttttc tgaaaatata gagtttaaag cgtgttgaac cataagttca
    43861 ggcattacct tccatgcttc tctagcagta gcattagcat tatgtgctcc atcaatttga
    43921 gctatattgg caaaagccat tattttcttt gcctcacaag catctacaaa agaccttacc
    43981 atgtttatat tcctatacag aacattatat tgtgggtctt gatgtgctcc attgactcct
    44041 tcctcagcaa acattactgc tacttcagga ccagcaacac cacttacata tgaatggtaa
    44101 ttaataggtc taccaacttc ttcttctata aaatcaagag ccttcctttg agctcttact
    44161 tgttttcttg ttattggaac tccacctata ccttgtggag ttccttctat aagcccatca
    44221 aaatgtgatt gtccagcagt tctgataacc attagatggt cagctccatg atgagctgcc
    44281 attctcattc ttcttatatc atcctcaaat ctaccagaag ctatttcagt agtaataact
    44341 ggacttggtt gagggtctat attattgaaa tacttagatg atggtagccc tacactcttc
    44401 tttaaaggtt ttgtacagtc tttatattta aaaggtccca tttcaagatt ttccaagtgt
    44461 tctctccaaa cccaacctct tcgttttggt ttatatttat ccaaatcttt taatatatag
    44521 tctatatcca attttttatt ttcctttaac atgattctac cccttctcta aataaacatg
    44581 taacttcatc ccaatattca cccttaacta ataacaaacc tgcttctcta accgttatat
    44641 ttttagattt agccaattta taaactacat gccctgctcc tttacctata agacctcttt
    44701 ccataacccc ttctaaaata ggttttactt caagagaaga aaatcccatt ctcaacaaga
    44761 cagacctttc tattgatggt gttgtattct ttttaccaag ttctatcatt ggttctacta
    44821 tctgggtagc taaactccaa aacctttctt ttaactcatc atcactcagt tcttgaagat
    44881 gttttcttct aacttcaaaa tcatcctctc tttttttcat gaacattcct ccattcgtat
    44941 tgatttaatc gaattttctg aatttttatt ttatattaaa ttaaaaaaca ataattacta
    45001 taaattattt aatacatcaa caacaaaatc tcttgaactt tttacttctt ccattaaaaa
    45061 ttctatatct cgattactta gcttatcaat attatcaatg tgattattag atatacaatt
    45121 ttttataaat gactttctta ttttattcat atcaatatca acacatttca ataattctgg
    45181 tctttctggt aatattaagt ttactcctgc aatttcttct cttggatttc caaattttat
    45241 atctattcca ttttctcttg caaaagtaag ctgtggacat atatgtttac ctgcgcctgt
    45301 atattctgtt tcttgtacca ctataacttt atcctcatct aactcttgag ctaaagagaa
    45361 tgctgctgct aaagatgtat ttcctgctgg acctctttct ataccttcta gctgtgccaa
    45421 taattcagtt gtataaaaaa cttctccttg ttttactaat acatatctat ccatatatct
    45481 aagtggtcta gctgcagacc taggtacatc tgacctatca ggccatgtac agtatggtat
    45541 cccaaaacct gtatgtcctg ttgtaaatga ttttttatta aattgattat cactagccat
    45601 gtgtaatcct tttaaatcta cacttgctcc tactacttta gtattaatag aaccagcttt
    45661 tatcaatcct cttgcagttc cagtaagatt accaccacct gcatttgtac aaacaactat
    45721 atcagggtct tttttatact tttctctaaa ttggatagct aactcataac ctaaagtttc
    45781 tacacctgca attccaaatg gtgaatataa tgatgcgtta aaatagcctg tttcttctaa
    45841 taaaactaag aacgtataaa ataactctgg tccaacagtt aactgaacaa cttctgctcc
    45901 atatgcctca cattttcgtg ctttttctat aatttcaggt tgacctacac cattagaatc
    45961 ataacattct tgaactatta tacattttaa tccctgcatt gccgcttgtg atgctacagc
    46021 tgcaccatag ttaccactag tagctgctat tacaccttta tatcccattt gtttggcatg
    46081 atatactgca gtagctgctc ttcttgcttt aaaactacca gatgcattca ttgcttcatc
    46141 ttttacaaat attctagctc ctttaccttc tttagcacat tttctagcta atttagtcaa
    46201 atttttaagc tctattaaag gagtatttcc aacagcatac tgtgattgaa ttgcttcaat
    46261 atcttgtaat gtatatcctg tttcactcat cattttctca taatcaaacc ctattccctc
    46321 ttgttcaaaa taagaataat ccaatccgat tgcatttttc attatttcgt tatttcttcc
    46381 cataacagct tgataactca tatctttcat tgatgttgaa ttattcatta tatacacctc
    46441 caaataatat ttctttagct tggattccta tttggagtaa ctctggtata catttaccat
    46501 aatcatgagt ataatatgga tttattttaa gtaaattacc ttttacaagt ctgcctgtaa
    46561 ttgttttaac ttctactaag tcgcctatag aagcatcact ttgtataaaa cctttaaccc
    46621 acatttctaa ggatactttc ttagtatcct ctggaacttg tggagctctt tcttctggag
    46681 tcaatactat attgtgtata ataacccaat cattaatttt agcatccatt ttttcatccc
    46741 cttattaatt gactattgcc ttactaatta atttactgtt attttaaatt aaacattatt
    46801 ttaccaatta gctaactgtt atcttactaa ttagctagtt gctatcttac taattagtta
    46861 gctgttatct tactaattag cctttgattc ttcttccaat tcaacttcta tctgatttct
    46921 tatatctccc attattgctc taggtactgg tatatccaac atagttttaa gacctggtct
    46981 agcatttatt attaatggaa tagagtttac tatcattgca taagtaccta ctcctccagg
    47041 tatttcagga tttatttgta aatcaatgtt tggtatacct tttattgata catagtctcc
    47101 tgttttaata ccttctgctt ctggtattat ctgttgtgga tgctccattt caattaaaac
    47161 ttctccattt acatatccat atccacattg tctacaacca gcaacatttc cagccaatgc
    47221 ctctccgtac ttagattttc tatctactgt agtcattatt ggctcttttg tttgttctat
    47281 cttatctaat ttccaaccta atccatcagc tatcatattt attgattcta caaaacctac
    47341 atgacctgct atagtcttat cttctacacc ttttataaat tcttcccttg ttactccaac
    47401 accttgttcc tccataacag actttccaaa tggagataaa tcatttactc tcttagcttt
    47461 tatactagta acttcttcac aagtgcctga aagcgccaat actagtaaat ctaatacaaa
    47521 tcctggattt attcctgttc caagtatact tactccattt tcctttgcaa cttcatccat
    47581 ttttttagct aaatctgcat catcagcttg tggatatgcc atttgttctg ctgttgatat
    47641 aacatttatt tttctattta ataagaaaat tattttatca aaagcctttt tagtaaatga
    47701 atcagttgct aacaaaacaa catctacact tttttctcta aaaacttctt cataattttt
    47761 attgataata acttctggtc tttctcctct ttcaattcct aaaacattat acatactttt
    47821 tcctgaagta cttctactac aaacagatac tatttctata ccttctttct ttagaatcat
    47881 attagccata cctattccca tagctccaaa tccccatatt cctactctta cttttctcat
    47941 atatacaccc tcctaaaaat ttatatattc tcaataatta gttaaagcat aaatcgtgcc
    48001 aactttaaaa ttaaagtaaa tatttattga aacgttgaaa ctataattat tttattatgt
    48061 attttcataa ataaaaaata atatttctta tgagaaataa aaaaaagagc aaaatatttt
    48121 gctcttttat aataattttg ctcctctatt ttgctttttt attttacttt gattttgttt
    48181 ttttatcttg cttatttata atattttgat attatatttt tttattttat actgtaaatt
    48241 ttgcctattc atacctaaaa ttgatgcagc tttagttata ttgtaagatg ccttttctaa
    48301 tgattcatat atatactttt cttctatctc actgataatc ttactaagtg ttttgtcctc
    48361 caaatcgttt aaagaataat tgttactctc tttattctct ttaagattgt aatagtcgtt
    48421 tagattaatc atacttgttt ctatttgtac ctcatcttcc atcatactca tagtacaata
    48481 aattatgttt tctagctctc ttatgttacc ttgccaatcg taatttttta aaattttaat
    48541 agcttcatct gaaattccta ctactttttt atttaacttt ttattatact ttgaaataaa
    48601 ttttttgcac aatagaggta tgtcctcttt tctatctcta agaggaggaa tttttatatg
    48661 aattatgtta agcctataat ataaatcttt tcgcatttta tgctcgttta aaattacctt
    48721 tggactttca tttgtcgttg caataattct tacatctata ggtatatcct tagttcctcc
    48781 aacccttctt acataacctt cttgtaaaac ccttaatagt ttagcctgta acataatagg
    48841 catggaattt atctcatcca ataacaatgt ccctttgtta gcttgttcaa ataagcctgg
    48901 cctatctatt gctcctgtaa atcctccctt gctagttcca aaaagaatac cttcgaatag
    48961 tgattccggc aaagctgcac aattttgtgc tataaatgga tagtttttcc tattacttcc
    49021 atagtgaatg gactggctaa ataactcttt acccgttcca gtttcaccgt atataaatac
    49081 tgaagcatca gacttgcaag ctttcttaga tttagctatt gcttctttaa tcaaattact
    49141 ttcccctaaa atatcatcaa attcataacc ctttttttgt ctaatactaa ctttattgac
    49201 taaatttttt ttataatttc tgtttagtaa attttctatc gttgtcatat tctttgatat
    49261 ctcaagtgcc cctacaaact cgcctttaat atcaattggt attgtagtat taattgctgt
    49321 tatctctctt ccatttttat ccagatattt ttgaatattg tctttgataa cttccctttt
    49381 ttccaaaact tctaatagtg tactcctgtt tattttcatt ttgttgacta tatcaaaaaa
    49441 tgaattggtt aaaatatcgt gtctgttcat tttttccatt ttttgtacag aattattgta
    49501 gattatagtt ttcccgtctt tattaacaaa atgtacccct tcatcaatat tttccaatat
    49561 ttcattcatt attttaaaaa atatctcttg gttcaactat atcaccccag tacctaaata
    49621 tataaaaacc caaaaaatta ataaaatgtt gctattgtat ttatcttatc atatattt
//
LOCUS       DAYAOO010000024        48754 bp    DNA     linear   BCT 12-OCT-2024
DEFINITION  TPA_asm: Clostridioides difficile isolate ST8-SSI-h139-18
            SAMN40601845-rid21577343.denovo.024, whole genome shotgun sequence.
ACCESSION   DAYAOO010000024 DAYAOO010000000
VERSION     DAYAOO010000024.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN40601845
            Sequence Read Archive: SRR28438827
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 48754)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 48754)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-MAY-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-MAY-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002157583.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002157583.1
            Genome Coverage       :: 163x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/11/2024 16:19:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 4,038
            CDSs (total)                      :: 3,963
            Genes (coding)                    :: 3,930
            CDSs (with protein)               :: 3,930
            Genes (RNA)                       :: 75
            rRNAs                             :: 6, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 60
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 33
            CDSs (without protein)            :: 33
            Pseudo Genes (ambiguous residues) :: 0 of 33
            Pseudo Genes (frameshifted)       :: 7 of 33
            Pseudo Genes (incomplete)         :: 25 of 33
            Pseudo Genes (internal stop)      :: 11 of 33
            Pseudo Genes (multiple problems)  :: 8 of 33
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..48754
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN40601845-rid21577343.denovo.024"
                     /isolate="ST8-SSI-h139-18"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Denmark"
                     /collection_date="2018"
                     /collected_by="Statens Serum Institute"
     gene            99..833
                     /locus_tag="ACGI5H_001478"
     CDS             99..833
                     /locus_tag="ACGI5H_001478"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435476.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HFG9697189.1"
                     /translation="MKQNKYDDDRFFNKYSKMERSTNGLAGAGEWHVLKKMLPDFKGK
                     RVLDLGCGFGWHCQYAVENGAISAVGVDISEKMLKEARNKTQLDNINYICMPIEDINF
                     PKDSFDVVISSLAFHYIQSFEDICKNISNCLSNKGNFVFSVEHPIFTAYGSQEWYCDK
                     DGTNLHWPVDGYFEEGVRKSNFLGEEVIKYHKTLTTYLNTLMKTGFEILEIIEPQPEE
                     KLLDTIPDMKDELRRPMMLLVSAKKR"
     gene            complement(976..1467)
                     /locus_tag="ACGI5H_001479"
     CDS             complement(976..1467)
                     /locus_tag="ACGI5H_001479"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prolyl-tRNA synthetase associated
                     domain-containing protein"
                     /protein_id="HFG9697190.1"
                     /translation="MNNQQQEVYKKLDELSIPYEAVNHPPVYTIEEMEELKTLHMEFV
                     VKNLFLRDAKGKEHFLVVLGKDKKADLKDIRQQIDSKPLSFASEERLQKYLKLTKGAV
                     TPFGILNDKEAVVKVVFDKDLLKMDKIGIHPNDNTATVFLKFEDMKKLIEENGNEIYY
                     VEV"
     gene            1816..2199
                     /locus_tag="ACGI5H_001480"
     CDS             1816..2199
                     /locus_tag="ACGI5H_001480"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428668.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PBECR2 nuclease fold domain-containing protein"
                     /protein_id="HFG9697191.1"
                     /translation="MSTDKVVGIIDEETAELAGIEYTGKIYASSGVIKHIKKKHRCQL
                     SKDIFNDIIDTIKMVLKSPEYIGSHPKKPGKSVEFIKKIDDYILVATELDTKKGYLYV
                     SSMYAIKEAKLESRVNSGRVKQYNG"
     gene            2707..3090
                     /locus_tag="ACGI5H_001481"
     CDS             2707..3090
                     /locus_tag="ACGI5H_001481"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428669.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YtxH domain-containing protein"
                     /protein_id="HFG9697192.1"
                     /translation="MNLSKKIEDKRKAKQRAEKVKKAKIATAGVVLGAVTGAVSGVLL
                     APKSGKETREDIKDASQQIAEKINMKTVDVKGKVSEKLEDKKGNFIESKKKIKKYIDN
                     KKSVENSSEEDKIIDIVEPVSVTEE"
     gene            3092..3442
                     /locus_tag="ACGI5H_001482"
     CDS             3092..3442
                     /locus_tag="ACGI5H_001482"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428670.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9697193.1"
                     /translation="MDNTITINISIIYVLLAILACIALVYLIIVLVKLHKILNNVGTM
                     LNENTQNINTTLNNLPNVVETFGEVGENMKDVTEVVTEVTADFLVTKDSVKSNMDVIV
                     DILTIIKNIFLDKK"
     gene            complement(3543..4001)
                     /locus_tag="ACGI5H_001483"
     CDS             complement(3543..4001)
                     /locus_tag="ACGI5H_001483"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435468.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9697194.1"
                     /translation="MIRTKVVELIATVCRENKPHKWVDENYTPYDKSGKVELMSIEDL
                     NELISSSGRADFLYSSRLQKLLEEVYINQSRASYISGCGLFWSSYWDILEEKFEEWLY
                     NSYIFFDEDDEYLEGMEDFELECKDVLMDVIETTSIDIYVQMIKRNITNY"
     gene            complement(4046..4834)
                     /locus_tag="ACGI5H_001484"
     CDS             complement(4046..4834)
                     /locus_tag="ACGI5H_001484"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729051.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase"
                     /protein_id="HFG9697195.1"
                     /translation="MKVVIIPGHTLIGKGTGAVGYINESKETRILNDLIVKWLKIGGA
                     TVYTGRVDESSNHLADQCAIANKQETDLAVQIHFNSNATTSTPVGTETIYKTNNGKTY
                     AERVNTRLATVFKDRGAKSDVRGLYWLNHTIAPAILIEVCFVDSKADTDYYVNNKDKV
                     AKLIAEGILNKSISNSQEGGENKVYENVIVYTGDADKVAAQILHWQLKDSLIIEASSY
                     KQGLGKKVYVVGGEANKLVKGDVVINGADRYETVKLALQEIDKL"
     gene            complement(4973..5410)
                     /locus_tag="ACGI5H_001485"
     CDS             complement(4973..5410)
                     /locus_tag="ACGI5H_001485"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897045.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytidine/deoxycytidylate deaminase family
                     protein"
                     /protein_id="HFG9697196.1"
                     /translation="MNKKLENRCSWQEYFMRLCETVAERGTCDRAYVGAIIVNSENRI
                     VSTGYNGSISGDKHCSEVGHEMRDGHCIRTIHAEQNALYYCAKEGISVKNCSIYVTHF
                     PCLNCTKAIIQAGIKHIYYRTGYRIDEYAIKLLQSSNVLYTKL"
     gene            complement(5644..5778)
                     /locus_tag="ACGI5H_001486"
     CDS             complement(5644..5778)
                     /locus_tag="ACGI5H_001486"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889851.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9697197.1"
                     /translation="MGILEGAAMIREIAIKIAKEKGITEQKAWPEAVKEFKEKYELVL
                     "
     gene            6232..6741
                     /locus_tag="ACGI5H_001487"
     CDS             6232..6741
                     /locus_tag="ACGI5H_001487"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905613.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HFG9697198.1"
                     /translation="MLSENIKTIRKSKGLSQQELAIKLNVVRQTISKWEQGLSVPDSD
                     MLISISEVLETPVSTLLGETIVESEVDNLKVISEKLEIINLQLAQRKNMRRKMFHWLF
                     ILLCAVILIVFVVLGGLNSPYLDWNYTDPETAVFGVAFHAFEWLFVRLVPIVLIGAII
                     GIFLTRKKI"
     gene            6768..6914
                     /locus_tag="ACGI5H_001488"
                     /pseudo
     CDS             6768..6914
                     /locus_tag="ACGI5H_001488"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005336078.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
     gene            7147..7683
                     /locus_tag="ACGI5H_001489"
     CDS             7147..7683
                     /locus_tag="ACGI5H_001489"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428676.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal peptidase II"
                     /protein_id="HFG9697199.1"
                     /translation="MQGGVNIRQVKSFVFPVISLIFLDQISKVLIGLFLMDFEIDIIG
                     KFLRFNPVQNTNLSYGGNFIGILSNLWVLVLFNILVILVIISGYAFYKSKNEQTSYSV
                     KVIMSCGLAGTICSLIDKLFWGGSLDFLQIPSFFIFDLKDCYLTVAEIIFVVIGILHN
                     REISMKEYIYFCYRQFKK"
     gene            complement(8110..8910)
                     /locus_tag="ACGI5H_001490"
     CDS             complement(8110..8910)
                     /locus_tag="ACGI5H_001490"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861383.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HFG9697200.1"
                     /translation="MRLNKRSEGYINYVKGVKREKRNVLFYQLLILIGFIVIWELLAD
                     LNVINTFLFSKPSDIYNLFIQYAFSGQLFKHIGISVYETVLGLVIGTVLGILVAIALW
                     WSEKLSKILDPFLVVLNALPKTALAPIIIVWVGAGIEGIVVTAVTISVVVTILSAYNY
                     FMNIDEEKIKMLKSFGATKSQILFKLILPANTGNLINLTKINIGMAWVGVIVGEFLVS
                     RYGIGYLIVYGSQVFKLDLVMMGVFVLAICAWAMYAVVNIIEKIYNSR"
     gene            complement(9105..10703)
                     /locus_tag="ACGI5H_001491"
     CDS             complement(9105..10703)
                     /locus_tag="ACGI5H_001491"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435445.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000150 - DNA strand exchange activity
                     [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HFG9697201.1"
                     /translation="MKAAIYSRKSRFTGKGDSIENQIQLCIDYAKSIGVKDFLIYEDE
                     GFSGSNIDRPQFKKMMQDAKDKKFSYLVCYRLDRISRNVSDFSTLIEKLNELSISFIS
                     IKEQFDTSTPMGRAMMFISSVFAQLERETIAERIKDNMYELARSGRWLGGNTPHGFNS
                     EKITFLDENLKERSMYKLQVNDEQMEIVKLIYNKYLELRSLSKLYKYVYNNGIRGPRG
                     GKFDPSSLSRILRNPAYVKANDEILDYLKNSGMDVVGTPDRKCGILTYAKNTSNSIAA
                     IAKHHGVIEPEIWLEVQNQLDKNRDKTPRISTGKTALLSGLIKCGKCGSNMRITYKGK
                     KTDKDLKYYYICGTKKTLGSDSCNCKNLNGPLVESLVIDKIKNCKEESIISAFNSNNI
                     KTDNVFNIFKSETNLLKNQILDKERLIKNLVIELAKNTGSTASDYIVSQIESLNNEIS
                     ILKDKINTLESSNINISSDSINIDIIVSNLKRFNDEVDNASLDDKRLLLSTIINSIVW
                     DSSLGNLNIVYMGAEVDNSVSLSN"
     gene            11031..11207
                     /locus_tag="ACGI5H_001492"
     CDS             11031..11207
                     /locus_tag="ACGI5H_001492"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435444.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9697202.1"
                     /translation="MEINVIEIFPKDKAKLNKIEMDKASWFVNIISKKYPKEALNEAF
                     STLEKELNISKANT"
     gene            11381..12511
                     /locus_tag="ACGI5H_001493"
     CDS             11381..12511
                     /locus_tag="ACGI5H_001493"
                     /EC_number="1.1.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729048.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004022 - alcohol dehydrogenase (NAD+)
                     activity [Evidence IEA];
                     GO_function: GO:0005506 - iron ion binding [Evidence IEA];
                     GO_function: GO:0030554 - adenyl nucleotide binding
                     [Evidence IEA];
                     GO_process: GO:0051144 - propanediol catabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="1-propanol dehydrogenase PduQ"
                     /protein_id="HFG9697203.1"
                     /translation="MNNFEIKTRIKFGEGSLKALQELKNKNVLIITDPFMVKSKTIDK
                     ITSNLINSTYQVFEEIVPDPPIEVVVAGIEAFKSINPDVIIALGGGSAIDAAKSIMDF
                     SKKILKINEVEFIAIPTTSGTGSEVTSFAVITDSQKKCKYPLVSDDLLPDMAILDPEL
                     VKTVPNFITADTGMDVLTHAIEAYVSTNSNDFSDALAEKAIKLVFKYLIKAYKDGNDI
                     EAREKMHNASCLAGMAFNQASLGINHSIAHVLGGKFHIPHGRTNSILLPHVIEYNSSI
                     VGYTNTTYSATAKKYAQIAELVGLGSANIRISVRNLVNEIKKLQKEMNMPTKLTQCKL
                     SLEDITNEEREIAKLAIKDTCTLTNPKVPTEDDIINILKNIK"
     gene            12752..13102
                     /gene="eutS"
                     /locus_tag="ACGI5H_001494"
     CDS             12752..13102
                     /gene="eutS"
                     /locus_tag="ACGI5H_001494"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893329.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ethanolamine utilization microcompartment
                     protein EutS"
                     /protein_id="HFG9697204.1"
                     /translation="MTEESKQRVIQEYVPGKQVTLAHIIANPNEDIYKKLGLVLDKKD
                     AIGILTITPSEASIIAADVATKASNVSLGFIDRFSGSVVISGDVSSVESALNDVLEVL
                     GNMLNFSSTKITRT"
     gene            13110..13559
                     /locus_tag="ACGI5H_001495"
     CDS             13110..13559
                     /locus_tag="ACGI5H_001495"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423975.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EutP/PduV family microcompartment system
                     protein"
                     /protein_id="HFG9697205.1"
                     /translation="MKNIIFMGKTGSGKTTLCQKLDQLELKYKKTQSVELYNNAIDTP
                     GEYMENRNLYNALITTSADAKIIAIVYDATQEENYIAPGFASMFCKDVIGIITKINKA
                     TENEVNIAYERLSLAGASQIFKIDTVDNIGLEKLFKYLEKYKNIDEV"
     gene            13661..14236
                     /locus_tag="ACGI5H_001496"
     CDS             13661..14236
                     /locus_tag="ACGI5H_001496"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428683.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator"
                     /protein_id="HFG9697206.1"
                     /translation="MGKKILLVDDEPLLRMDTKDILESHGYEIIGEASDGFEAVEMCK
                     KHKPDLVIMDIEMPILDGIKAGKIICKENIAGGVLLLTSFEDKEYVEKAKSIGAYGYL
                     VKTASEKSLIPTIEMCLNKVNEFEKMKKDLEKVNSKLNERKLVERAKGILIREFKISE
                     DEAYTRIRKLSMDKRTTMMEIAKMIIIGYDD"
     gene            14229..15638
                     /locus_tag="ACGI5H_001497"
     CDS             14229..15638
                     /locus_tag="ACGI5H_001497"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423979.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine kinase N-terminal domain-containing
                     protein"
                     /protein_id="HFG9697207.1"
                     /translation="MTNTIKKISTAQTYLNNNEIEKIIEVSKSLDLMASFYEADVFID
                     VLSKFDDEAIVVAHGRPKEKSMYCENVIGKKALIENEPGVIKCLKTGERVRDIKALTQ
                     EYKLVKQNIQPITLDDKVLAVLIVEKDISSEVKNEFNASEDEENKNLHQFIKLIGNND
                     FLVDNLNSAILIFDKNGKLKIKNRIATEIYKNLGFGYDIQDMHYNDLDIETNTFENIL
                     MDENYDETNEVSIGNMFFKIKTIYIKDDEFKVCKIVQDISDLKRKEEELVLKTVAIRE
                     AHHRVKNNLHTVISIIKKQSRLSQNDEVKQCLDNIINRVFAILSTHYLLSKEVDNNIS
                     IREGINLLVSNIQGGYLFSKDIDIRITGEDFKISGEKATAILLVINEILQNCYDHAFS
                     DREHGTIQILINKDNDYRNIAIIDDGIGFDSNNINKNSLGTYIIDSYITQMLKGNIER
                     KSSENGTEVLITIPTQINI"
     gene            15822..17255
                     /gene="eutA"
                     /locus_tag="ACGI5H_001498"
     CDS             15822..17255
                     /gene="eutA"
                     /locus_tag="ACGI5H_001498"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729047.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ethanolamine ammonia-lyase reactivating factor
                     EutA"
                     /protein_id="HFG9697208.1"
                     /translation="MREELLSVGIDIGTSTTQLIFSKLIVENTESNFSVPRISIVDKE
                     IIYKSKVYFTPLISNNEINGQQIKDIVENEYKKANISKEDIHTGAVIITGETARKENA
                     NDVLHTLSGFAGDFVVATAGPDLESIISGKGAGAHIYSKEHSTTIVNIDIGGGTSNIA
                     SFKRGEVTDTGCLDIGGRLVKIDKISKKITYISPKIDKIIKDNNLNLQVGTMATVENT
                     KPIVDIMVDLLMESIGLKKQTPLFDFIITNKSISIDENIKNVSFSGGVADYIYYDGEI
                     KDYFEYGDLGILLGQAIKNCEYLKKVNVVKSMETIRATVVGAGSHTTEVSGSTITYTS
                     EKFPLKNLPVLKLSIDEETGTSKQISEAIKNKLNWFKLENDLQKVAIAMIGKKNPTFL
                     DIQEYAKGFVDGMQQIIENDLPFIVIVENDMAKVLGQAIYALLNYEKEIVCIDSVKVE
                     NGDYIDIGKPIVEGKVLPVVIKTLVFN"
     gene            17273..18637
                     /locus_tag="ACGI5H_001499"
     CDS             17273..18637
                     /locus_tag="ACGI5H_001499"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435424.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ethanolamine ammonia-lyase subunit EutB"
                     /protein_id="HFG9697209.1"
                     /translation="MILNTKLFGRTYQFKGLYDVMAKANEEKSGDKLAGLAAESAEER
                     IAAKVVLSHIKLEDIRNNPAVAYEEDEVTRIIQDAVNEKVYEEIKNWTVSELREWLLD
                     SNTTSLDIRRISRGLTSEMIAAVAKLMSNMDLVYAAKKIKVTAHCNTTIGEQGTLSAR
                     LQPNHPTDDPDGILASLLEGLTFGIGDAVLGLNPVDDSVESVTKVLKRFEEVKQKYQI
                     PTQTCVLAHVTTQMEAIRNGAPADLIFQSIAGSEKGNEAFGFNGDTIEEARQLALKHG
                     TATGPNVMYFETGQGSELSSEAHHGIDQVTMEARCYGFAKKYEPFLVNTVVGFIGPEY
                     LYDAREVVRAGLEDHFMGKLHGLPMGVDVCYTNHMKADQNDMENLAILLTTAGCTYFM
                     GIPHGDDVMLNYQTTGYHETASLREMFGLTAIKEFDAWMEKMGFSKDGKLTELAGDAS
                     VLLG"
     gene            18650..19531
                     /gene="eutC"
                     /locus_tag="ACGI5H_001500"
     CDS             18650..19531
                     /gene="eutC"
                     /locus_tag="ACGI5H_001500"
                     /EC_number="4.3.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008851 - ethanolamine ammonia-lyase
                     activity [Evidence IEA];
                     GO_process: GO:0006520 - amino acid metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ethanolamine ammonia-lyase subunit EutC"
                     /protein_id="HFG9697210.1"
                     /translation="MNEKDLKALVEQLVGQMVGELDTNVVSETVKKATEVVVDNNACI
                     DDITEVDIRKQLLVKNPKDAEAYLDMKAKTPARLGIGRAGTRYKTETVLRFRADHAAA
                     QDAVFSYVDEEFIKENNMFAVETLCKDKDEYLTRPDLGRKFSPETINNIKSKFGTNQK
                     VLILVGDGLSSAAIEANLKDCVPAIKQGLKMYGIDSSEILFVKHCRVGAMDHLGEELG
                     CEVICMLVGERPGLVTAESMSAYIAYKPYIGMAEAKRTVISNIHKGGTTAVEAGAHIA
                     ELIKTMLDKKASGIDLK"
     gene            19551..20204
                     /gene="eutL"
                     /locus_tag="ACGI5H_001501"
     CDS             19551..20204
                     /gene="eutL"
                     /locus_tag="ACGI5H_001501"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423987.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0031469 - bacterial microcompartment
                     [Evidence IEA];
                     GO_function: GO:0005198 - structural molecule activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ethanolamine utilization microcompartment
                     protein EutL"
                     /protein_id="HFG9697211.1"
                     /translation="MKNDVIRPNILGIKIISNISPEMAQKLELKSHHKSLGLITADCD
                     DVTYTALDEATKASEVDVVYAKSMYAGAANASTKLAGEVLGIIAGPSPAEVRSGLNAV
                     VDFLEYGATFISANDDDSIAYYAHCVSRTGTYLSEVAGIREGEALAYLVAPPLEAMYA
                     LDAAMKAADVKMCELFAPPTETNFGGALLTGSQSACKAACDAFAEAVKSVADNPTGF"
     gene            20215..20916
                     /locus_tag="ACGI5H_001502"
     CDS             20215..20916
                     /locus_tag="ACGI5H_001502"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428690.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BMC domain-containing protein"
                     /protein_id="HFG9697212.1"
                     /translation="MDAIGLIEVIGYVAAIEASDACLKSANVNIVRVDKVGAGIVTLT
                     ICGDVGAVKAALEAGEIAASRVGTLRTSHIIPRIHNEVTNALFKTKEPKVCEVSEDKE
                     KNFEITLEIADNVSKNLSEKENVILDVNENSGDTENLYSDIDKTNKKIETVDDSLTEA
                     NEEKIENTNDKEVLEQVKIENSDFDRDDLSKNSVKKLKAMAKKLDSSITYKDLNVLKK
                     EELINLVKKLSRRDR"
     gene            20919..22388
                     /locus_tag="ACGI5H_001503"
     CDS             20919..22388
                     /locus_tag="ACGI5H_001503"
                     /EC_number="1.2.1.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889875.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016620 - oxidoreductase activity, acting
                     on the aldehyde or oxo group of donors, NAD or NADP as
                     acceptor [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="acetaldehyde dehydrogenase (acetylating)"
                     /protein_id="HFG9697213.1"
                     /translation="MTLLDKDLVSIQEVRTLVRRSKVAQEKLSKMSQEQIDKIVKAVV
                     DAAFNNATKLAKMANEETGFGKWEDKVIKNTFASMGVYETLKNTKTIGIIGEDKEANT
                     IDIATPVGVVAGLIPSTNPTSTVIYKTIISLKAGNTIVFSPHPNAKNCILETVNIISD
                     AAIKAGAPEDSILCITNPSIVGTNELMKHKDTNLILATGGEAMVRAAYSSGTPAIGVG
                     PGNGPAFIDKSANVKLAIKRIIDSKTFDNGVICASEQSIVIEKSMEETVLKELKNQGA
                     YVLNEEESERLAKFILRANGTMNPQIVGKSVEVIANLADLTNVPKNTKVLVARENKVG
                     HNVAYSREKLTPILAFYVEENVEAIMNRCREILLNEGAGHTFSMHVNDEELVKRFALN
                     MPVSRILVNTPSALGGIGASTNLVPALTLGCGAIGGSSTSNNIGPLDLINVKRVAYGI
                     KEIEELGRDKSQVEKSMFDSMDKEELINLLVQKLVKELA"
     gene            22484..22771
                     /gene="eutM"
                     /locus_tag="ACGI5H_001504"
     CDS             22484..22771
                     /gene="eutM"
                     /locus_tag="ACGI5H_001504"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423991.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ethanolamine utilization microcompartment
                     protein EutM"
                     /protein_id="HFG9697214.1"
                     /translation="MASANALGMIETKGLVGAIEAADAMVKAANVQLVGKEQVGGGLV
                     TVMVRGDVGAVKAATDAGAAAAERVGELISVHVIPRPHFEVDAILPKVSAE"
     gene            22898..23659
                     /locus_tag="ACGI5H_001505"
     CDS             22898..23659
                     /locus_tag="ACGI5H_001505"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729043.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cobalamin adenosyltransferase"
                     /protein_id="HFG9697215.1"
                     /translation="MGVLTENEVKRKIGKNKNNITEFYIEKGQIITPSAKSYLAERSI
                     ELKYVDKLSDVNNEPKEVVKEVVKEKKYRYTTVFGAKLDEKPEHMTQLNGNLLVFKDH
                     KRIILRGKIDSLESEILKVQILCQKLDMPKLVKELQEVLDFVRNIMRCEVLDEKLGDF
                     KLLGLTPQELREQSHYPKKYFGIGHEFPSYEMGEVVVAINSIRSNTREVELAAYEAFK
                     GEYGNVHREDLIKALNRLSSVFWIMIYKVRTNKYK"
     gene            23672..24301
                     /gene="eutD"
                     /locus_tag="ACGI5H_001506"
     CDS             23672..24301
                     /gene="eutD"
                     /locus_tag="ACGI5H_001506"
                     /EC_number="2.3.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902845.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ethanolamine utilization phosphate
                     acetyltransferase EutD"
                     /protein_id="HFG9697216.1"
                     /translation="MENLLNEIVEEVITRVKKEAFIEVEASGRHVHLSREDVDKLFGE
                     GYTLTKLKDLSQPGQYACKERVTITGPKGSIKNVVVLGPCRNETQVEISLTDGSTLGL
                     KAPIKQSGDLEGTLSIKISTQYGEVELDKGLMVAKRHIHMTHKDAEKFNVCDKEIVEA
                     KVMGQRPLTFDDVVIRVSDSFKTYMHIDYDEANACGYSKGTVAKIIKKA"
     gene            24343..25068
                     /locus_tag="ACGI5H_001507"
     CDS             24343..25068
                     /locus_tag="ACGI5H_001507"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435412.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR02536 family ethanolamine utilization
                     protein"
                     /protein_id="HFG9697217.1"
                     /translation="MNYDNLVDLITEEIYKKINSNEIKISNKPKAVIVFEQDNNKFNL
                     LKDEFEIVEFDKSIRECEIVIVSRLCMRGLSNIALGNSTSDEERFILKMIMKGKEVYV
                     LDEGIEYKKYKDTAPKALYKKFMSFEDEICKFGVEIIKDLNVITKNKLNIKKELESTR
                     GSKKEDTKVLDKDVLNLTSVESVKIDNEFSLDLRNKKLISEADLRKPTINGVKNILVN
                     KKSIITPLAVDFMRIHHLKLKKV"
     gene            25081..25353
                     /locus_tag="ACGI5H_001508"
     CDS             25081..25353
                     /locus_tag="ACGI5H_001508"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435411.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EutN/CcmL family microcompartment protein"
                     /protein_id="HFG9697218.1"
                     /translation="MDIGKVVGNVWATRKDEKLCGQKLLVVKILKTKDTYKEGFMVAA
                     DNAGAGNGDLVLISKGSSARESIEKSHVPVDATIVGVVDSFEVFDE"
     gene            25346..25897
                     /locus_tag="ACGI5H_001509"
     CDS             25346..25897
                     /locus_tag="ACGI5H_001509"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729042.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0031469 - bacterial microcompartment
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="BMC domain-containing protein"
                     /protein_id="HFG9697219.1"
                     /translation="MNKSIGAIEFKSIAKGIEVSNEMIKKSSVDVLYLKSICPGKFLI
                     IVGGETSYINECVDYGIKLGEGYIVDNFVINAISQEILDGFKNKYQKLDSIVSIGVVE
                     SSKVCAGIKMLDKTLKSGDLVLVKLQLSFAIGGKLVYIVAGDLSSLEYALKESENVVR
                     EKEVIYKTVIPSVDSQIIKSLIK"
     gene            25909..27000
                     /gene="eutH"
                     /locus_tag="ACGI5H_001510"
     CDS             25909..27000
                     /gene="eutH"
                     /locus_tag="ACGI5H_001510"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889882.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ethanolamine utilization protein EutH"
                     /protein_id="HFG9697220.1"
                     /translation="MSINEIIIYVMVVFMVLGAIDKCIGNKFGLGEQFEEGIMAMGSL
                     AVAMVGVICLAPVLADVLRPIVVPVFNILGADPAMFAGSLLANDMGGAPLALELAKDP
                     NAGLFGGLIVGAMMGPTIVFIIPVALGIIEKEDQKFLATGILAGIITIPIGAFVGGLV
                     AGFEVMMVLRNLVPIIIFAVVIALGLLKFENAMIKGFTYFGKGVVIVITLGLAAAIVE
                     ALTGIVVIPGMKPISEGIEIVGDIAIVLAGAFPLVFVITKVFNKPLMALGKVLGMNDV
                     SAAGLVASLANCIPMFGMMKDMDNRGKIINVAFSVSAAFVFGDHLGFTAGFNSNMITP
                     MIVAKLVGGITAVLLAMVIANKTLKKENV"
     gene            27002..27475
                     /locus_tag="ACGI5H_001511"
     CDS             27002..27475
                     /locus_tag="ACGI5H_001511"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893336.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cupin domain-containing protein"
                     /protein_id="HFG9697221.1"
                     /translation="MDISNIDKNLIETLVRQIIEEKISGTKDTVDFVRNKDISGITSI
                     KLPTVKVSESDRLDTGNPSDVVYTKDLFTLEESPRLGCGMMEMKETTFDWTLNYDEID
                     YVIDGTLDIIIDGRKVSASSGELIFIPKGSKIQFSVPDYARFIYVTYPADWASQN"
     gene            complement(27595..27690)
                     /locus_tag="ACGI5H_001512"
     CDS             complement(27595..27690)
                     /locus_tag="ACGI5H_001512"
                     /inference="COORDINATES: protein motif:HMM:NF012392.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HFG9697222.1"
                     /translation="MGYPNVEHFIRLFNKKYNMSPSKYRKNTSKI"
     gene            27991..28512
                     /locus_tag="ACGI5H_001513"
     CDS             27991..28512
                     /locus_tag="ACGI5H_001513"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889887.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HFG9697223.1"
                     /translation="MEEIVKKEQASMNDIFLYLKAKSNSLYKFVILYNEFINKPKDYG
                     TGELINMVEVHMLTAIEENPGISPTQLAKIWNRTKGAISQTISKLEKKGYITKEKKEG
                     NAKTILLYPTTSGVELSKAHKLYDTIDVTRTFEYLIKECTLEEIDSFYKVIDLFINLL
                     EESPQENNDSEKV"
     gene            28891..30066
                     /locus_tag="ACGI5H_001514"
     CDS             28891..30066
                     /locus_tag="ACGI5H_001514"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889888.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M20 family metallopeptidase"
                     /protein_id="HFG9697224.1"
                     /translation="MNLKQLSEKYEEYVIQMRREFHKYPELSFKEIRTTQRIREELQK
                     IGVPFVSIEPNIVIATIQGKNEGKTIAIRGDIDALPMQEDSDVEYKSEYDGIMHSCGH
                     DAHGAMLLGLAHMLNDIRKDLKGRVLLVFQAAEEVGGGHKEIIQYFKENGGPDRLIAT
                     HVWSDIEAGKISVEPGPRMAGGSGWRIDITGRGGHGSRPDQSIDPIKPACDIVLKVSS
                     IPVNHISVLEQCVVHACAIHGGTTIGNVIPNNAEVIGGYRYFTEESGKKVFDIIKQMS
                     NGVGQVYGVDVKVTHTGGIGPVINDEEAVKMAKEIVSNIDGLELDSYEPICASDCYGE
                     ILKEYSGFYCYLGVGNKEKGIIYAQHHPKYNIDEDTLKLGCEFMAKYAVEFLNKNNN"
     gene            30101..31639
                     /locus_tag="ACGI5H_001515"
     CDS             30101..31639
                     /locus_tag="ACGI5H_001515"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889889.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AbgT family transporter"
                     /protein_id="HFG9697225.1"
                     /translation="MQGALKENKKKSGGGFLGWIEKVGNKMPHPLALFTYITLIVVAL
                     SAIASFLGFSATSPATGKLIKVMNLISAKGLVLFMQEFVKNFQNFPVLGVVLVMAVAT
                     GVCEKTGFFSTAIKMSLSKVKGNAVVFIIAFIGVFANQAGDAAFVLVPTLAGAIFYGL
                     NRNPLAGIFCGFASVGGGFATAVIPGGWDVTLTPITVSAAQTIQPAFDMTLLASYYAL
                     FVSAFIVATVSTIVTVKFIEPKLGKYTGKPEGIDDNQGFEVTKEQAKAAKLAGFTVLA
                     YVALLIALCIPANSFLRSPEGSLIFGAPLMSCLQFFIVILFFLPGIVYGMRVGKIKTV
                     KDLNDILCQSMAAMAPFIVLAIVIGQFLTLFSVSNLAQVLAIKGGALLNSLPLPPQAI
                     ILLFLVLVAFINIFVISGSTKWMIFGPVFVPMLMQLNIHPAFTQFVYRLGDSVTNHLS
                     PLNAFFIILLATVQKYDKNAGMGTIFSAMIPYTIGYFVVLAVLVVVWMTIGIPVGIGG
                     QVWL"
     gene            31671..32873
                     /locus_tag="ACGI5H_001516"
     CDS             31671..32873
                     /locus_tag="ACGI5H_001516"
                     /EC_number="4.4.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889890.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA];
                     GO_function: GO:0047804 - cysteine-S-conjugate beta-lyase
                     activity [Evidence IEA];
                     GO_process: GO:0009086 - methionine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MalY/PatB family protein"
                     /protein_id="HFG9697226.1"
                     /translation="METTEIRYNFDEVIDRSGTNCLKYDLKSQFMPESPEDALPLWVA
                     DMDFACAPEIINAMHERIDRKIFGYSSQQTDDYYEAVCGWFKRRFDWKIEKENIFFSP
                     GVVPALGFFTQILTQKGDGIIIEKPVYYPFEDKITNNERKVVNSPLKFEDGHYSMDYD
                     GFEELAKDENNKVFILCSPHNPVGRVWKKEELRKIVDICKKYDLWIISDEIHCDIIRK
                     GEKHIPLEVACPDYKDRIITCTAPSKSFNLAGMQLSNIVINNKELQKKWMLETDSKLA
                     IFLPNPFAIVATKVAYNDCEDWMNQVNEYIDGNIKYVEDFVNEYMPKVKIIKSQGTYL
                     VWLDFRGYGLDAKQLEYVMLNKAKVLLDEGYIFGEEGAGFERINVASPRTIIEECMNR
                     IKCAFEGL"
     gene            complement(33040..33639)
                     /locus_tag="ACGI5H_001517"
     CDS             complement(33040..33639)
                     /locus_tag="ACGI5H_001517"
                     /EC_number="7.6.2.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435382.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HFG9697227.1"
                     /translation="MNDNIVEVKNINMNFYTKEGELEVLKDVNFNLKEGEILTLLGPS
                     GSGKSTILNILTNLLKPTSGDIKITGNIGYMFQKDNLLEWRNIMDNITIGLEIQGKKD
                     KKSLDRVESLLKTYGLWDFRSMYPKELSGGMRQRVALIRTLSVNPDILLLDEPFSALD
                     YQTRLLVCDDVYSIIKNENKSTILVTHDIGEARCIKVQL"
     gene            33809..35167
                     /locus_tag="ACGI5H_001518"
     CDS             33809..35167
                     /locus_tag="ACGI5H_001518"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729040.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9697228.1"
                     /translation="MSNIITNLIESIFTNPITILFLLAITVYSVFKIIENNRVYSFVS
                     SKLDEINRDYKTSEFYKKVRDDYYTYSKENPYADVNITSFIEEVVSDLKHNNLPLLEK
                     IRSIKNSSSISILLGVLGTFVGLSTMLLCVDTKDIINSLPSTISSMQTAFTTSIFGVV
                     FSLIIGYFTKIKDCEHVLIQIMLKSENLLTSEITHFKSERMDLKVEEVKNTIKQISKS
                     IEAIEKFDKISKDLNDFNDEFISGIEALKSLLEGSQSSIKTFDQSVRKLDKQFNILNI
                     KFVKLFDKYDNQDNINKEILFDIKESSKNIYNATESQFKIRDYIKNINAGFALYERSA
                     QDLLTKLMTHENKISQNQKILLDEKFTLDDSIKNLSSIIENFSNDLQVKLDMMFENSL
                     DIQDKLDVMFNNSFMNDEVPLDSEELFKDDVNNVFNPFSEEIYEIEDKEIKVIGEDEL
                     NE"
     gene            35160..35792
                     /locus_tag="ACGI5H_001519"
     CDS             35160..35792
                     /locus_tag="ACGI5H_001519"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424014.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="OmpA family protein"
                     /protein_id="HFG9697229.1"
                     /translation="MNNKYRRTVNREFEKSSFWPTFTDLLSTVLMVVILILFSSESIS
                     GSVEQDLAKNVNASVEETFKKSGIPVKVDKSNGQVTFGEKTMFDVDSDVLKPEAKEML
                     KMFVPKYIETIYKDYGDYISKIVIEGHTDDVGSYIYNLDLSQRRAYSVAKFIVGDEIG
                     DYKYKDKVTKHIIAIGRSKAELIKNGDNSVNRDASRRVELKYEININQNK"
     gene            36121..37278
                     /locus_tag="ACGI5H_001520"
     CDS             36121..37278
                     /locus_tag="ACGI5H_001520"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435380.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_process: GO:0030420 - establishment of competence for
                     transformation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ComEC/Rec2 family competence protein"
                     /protein_id="HFG9697230.1"
                     /translation="MIEISIKNKKNSKIKTLILLLIVSISIYLTGCTTSDNGNNQSNN
                     NDSLSSSISSDKNVKIHFIDTGNSDAILIQDGKTFTLIDGGDNDDEGLMVDYLNNQGV
                     KDIKYLIATHSHADHLGGLDSVVKNFNIENVFVSNGSAETKSYRDFINALANKGLSPS
                     VPLENNKFYLEDSYFEVLNTNGGDTTNEQSLVLVYTNGNDKVLFTGDAEEGTEKEILP
                     KLEKVDLLKVAHHGSRSSSSQEFLDKVNPEYAVLLVGKGNSYGHPHQETMNKLKKMGV
                     KVHRSDECSDIIFESTGDGVFTSCKDGSYNKGVREDGNSGKSNSNTSKNDSFKNKQNT
                     SNSEEIVYFTPKGKSYHSTKNCSGLSRSKKILSGTIAESKKNDPCDICYGK"
     gene            complement(37425..38060)
                     /gene="lexA"
                     /locus_tag="ACGI5H_001521"
     CDS             complement(37425..38060)
                     /gene="lexA"
                     /locus_tag="ACGI5H_001521"
                     /EC_number="3.4.21.88"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897067.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004252 - serine-type endopeptidase
                     activity [Evidence IEA];
                     GO_process: GO:0009432 - SOS response [Evidence IEA];
                     GO_process: GO:0045892 - negative regulation of
                     DNA-templated transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional repressor LexA"
                     /protein_id="HFG9697231.1"
                     /translation="MYLDLTEKQVLILEFIKSQIILKGYPPAVREICTAVGLRSTSTV
                     HSHLNKLEKLGYIRKDPTKPRAIEVLERSKVNDVSGANQEIIELPLVGQITAGEPILA
                     QQNIEEYIPFPASLVKGSNNFVLRVKGESMINAGILDEDYVVVDKKNTALNSQIVVAL
                     INGESATVKRFFKEGNLIRLQPENDFMEPIMLNDSEVEIVGIVTGVFRVIK"
     gene            complement(38164..39291)
                     /locus_tag="ACGI5H_001522"
     CDS             complement(38164..39291)
                     /locus_tag="ACGI5H_001522"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435347.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HFG9697232.1"
                     /translation="MNNDKKIIKVHNKSDKPDNIVIKENELIEKCLLLENKLPVFMKD
                     YFIYLKGSVAVSTRLAYLEDINFFCSYLIETKELTNADCVKDITEDDFNTIKSRDINL
                     FLGDYCSRYYKNTEKNTLIFENNNRALARKKSSISTLFKFLYRNSQIDNNITDGFNPI
                     KLPKPQPDAIKRLEIDEVAKMLESVETGEGLTEKEKVYWRKTKLRDKAILALFVTYGL
                     RLNELRELNISSFNFSRGEFKIYRKRGKEVLMPINHTCEHVIKDYLQNERTRDELLND
                     EEKDALFLSLQNKRITAKAIRTLVKKYTSIPLDTTRDNGYSPHKLRATAATSLIQTGF
                     SIYDVQNLLDHDNVTTTQLYAAHKKNVKRDIVKNFEWIEDD"
     gene            complement(39602..40447)
                     /locus_tag="ACGI5H_001523"
     CDS             complement(39602..40447)
                     /locus_tag="ACGI5H_001523"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424033.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9697233.1"
                     /translation="MIYIIEILKISVINIFCFIGIFIVFGLIFSITENLNNKFIFSSF
                     GKTGIIVTGAIGTFVHELSHLIMCLIFMHKINSVKFFRPIESKNDGILGYVSHSYKKD
                     NLYQSIGNFFIGIAPIIGGTIMIILIFKILLPDSYMKVTQNIDLKLYVSMINNLNING
                     FIHIILGDISNFIRIMLLTPSVYSLKYFIFMFLMYSISTHMSLSSADLKNSLNGLSFI
                     VIVIFVISSITYLFGFDNLNISSLIVKYNIFISFFMAIGFIFSIVTLIISYILSLVSP
                     FKNFS"
     gene            complement(40477..40848)
                     /locus_tag="ACGI5H_001524"
     CDS             complement(40477..40848)
                     /locus_tag="ACGI5H_001524"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889900.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ACT domain-containing protein"
                     /protein_id="HFG9697234.1"
                     /translation="MKLKLLVEEYAVCRLNNDSKIPTWIDTEKFYSITRTDDELSVVC
                     LNNNIPSDVKSEKEWRILKILGPLDFSLVGILSKLSSLLADNKISIFAISTYDTDYIL
                     VKEKDIENACKILSCNGYEVE"
     gene            complement(41001..41261)
                     /locus_tag="ACGI5H_001525"
     CDS             complement(41001..41261)
                     /locus_tag="ACGI5H_001525"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003866776.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="stage V sporulation protein S"
                     /protein_id="HFG9697235.1"
                     /translation="MEVLKVSSKSNPNSVAGALAGVLRERGVAEIQAIGAGALNQAIK
                     SIAIARGFVAPSGMDLVCIPAFTDIEIEGDKKTAIKLIIEPR"
     gene            complement(41450..42394)
                     /locus_tag="ACGI5H_001526"
     CDS             complement(41450..42394)
                     /locus_tag="ACGI5H_001526"
                     /EC_number="6.4.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424062.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009317 - acetyl-CoA carboxylase complex
                     [Evidence IEA];
                     GO_function: GO:0003989 - acetyl-CoA carboxylase activity
                     [Evidence IEA];
                     GO_process: GO:0006633 - fatty acid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase carboxyltransferase
                     subunit alpha"
                     /protein_id="HFG9697236.1"
                     /translation="MIENNSEKIKVLENDIKQLITISKANNIDLSDKINSLNEKLEKL
                     KEDAFSHLSAYEKVTLSRDIKRPTTLEYIEHICSNFLELHGDRLFKDDPSMVGGIGQI
                     GKFNVTIVGHQKGRDTKENIKRNFGMPHPEGYRKALRLMKQAEKFNRPIITFIDTSGA
                     FCGLEAEERGQGEAIARNLLEMSKLSVPVITFVIGEGGSGGALGIGVGNDVCMLEHSV
                     YSVISPEGLSSILFKDSSKAKEACDVMKLTSNDLYDLKIIDKIIKEPLGGAQKDVEAV
                     SKEIKAYILERLNHYKDMDKEEIIAQRYKKFRNIGKCL"
     gene            complement(42415..43269)
                     /gene="accD"
                     /locus_tag="ACGI5H_001527"
     CDS             complement(42415..43269)
                     /gene="accD"
                     /locus_tag="ACGI5H_001527"
                     /EC_number="6.4.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424064.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009317 - acetyl-CoA carboxylase complex
                     [Evidence IEA];
                     GO_function: GO:0003989 - acetyl-CoA carboxylase activity
                     [Evidence IEA];
                     GO_process: GO:0006633 - fatty acid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase, carboxyltransferase
                     subunit beta"
                     /protein_id="HFG9697237.1"
                     /translation="MIKKFLSSKESKYVTISLDDNFKKNSVDDKFWTYCKGCDSHVFR
                     KDIEENSFVCPKCSRHYGLRARKRINLLIDKGTFMEFNSDVEFQNPLNFPKYKEKVDS
                     YKEKTKESEAVVTGYGRINGIKTVICVMNPDFMMGSMGSIVGEKITYSIEYAAENNLP
                     IIICSASGGARMQEGMVSLMQMAKTSQALSKLEEKSLPYISVLTDPTTGGVTASFAML
                     GDIIISEPNTLIGFAGPRVIEQTINQKLPEGFQTSEFLLEKGFIDMIVDRRKMKEVLY
                     QILAMHKK"
     gene            complement(43284..44645)
                     /gene="accC"
                     /locus_tag="ACGI5H_001528"
     CDS             complement(43284..44645)
                     /gene="accC"
                     /locus_tag="ACGI5H_001528"
                     /EC_number="6.3.4.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424066.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009317 - acetyl-CoA carboxylase complex
                     [Evidence IEA];
                     GO_function: GO:0004075 - biotin carboxylase activity
                     [Evidence IEA];
                     GO_function: GO:0016874 - ligase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase biotin carboxylase
                     subunit"
                     /protein_id="HFG9697238.1"
                     /translation="MIKKILVANRGDIAVRIIRTCKELGIKTVAIYSEIDKDCFHRYI
                     ADESICIGPNNISKSYNNIENIIYLALKLKCDAIHPGFGFLSENPEFAKQCEDNNIIF
                     IGPTREQMILMGDKSRARETMMELNIPVVPGSESVLKTKEEALEVAREIGYPVMIKAS
                     SGGGGKGMRIVRKEEELFSNFDMASSEALAAFSNSDLYMEKFIENPRHIEVQVFGDKH
                     SNAIHLGDRDCSMQRRNQKVIEESLSPYLSDEERQKLHKIAVDIVKGVGYIGAGTIEF
                     IVDKDKNFYFIEMNTRIQVEHPVTEMVTNLDLIKLQISIANGDKIPFKQEDITFRGHA
                     IECRINAEDSSKNFAPSPGKIESLNLPGGFGVRFDTFVYAGYTIPPLYDSMIGKLICW
                     AETREECISRIYRALDEIIVEGINTNVEFQKALVTSEEFREDTHHTKFIEDVFMKKEF
                     ATL"
     gene            complement(44661..45113)
                     /gene="accB"
                     /locus_tag="ACGI5H_001529"
     CDS             complement(44661..45113)
                     /gene="accB"
                     /locus_tag="ACGI5H_001529"
                     /EC_number="6.4.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424068.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009317 - acetyl-CoA carboxylase complex
                     [Evidence IEA];
                     GO_function: GO:0003989 - acetyl-CoA carboxylase activity
                     [Evidence IEA];
                     GO_process: GO:0006633 - fatty acid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase biotin carboxyl carrier
                     protein"
                     /protein_id="HFG9697239.1"
                     /translation="MNINEIKELLKAIDSTNLEYVKLESSDLRLEVSKKAQSTSSPVL
                     SVQQESVVDLSLEKPVVNDTPVTSNENLSVVVAPLMGTFYDSPSPDADSFVKVGDVVE
                     EGDTLCILEAMKLMNEITSEIKGEIIEVLVSNEELVEYNQPLFKIKPL"
     gene            complement(45383..45829)
                     /locus_tag="ACGI5H_001530"
     CDS             complement(45383..45829)
                     /locus_tag="ACGI5H_001530"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435332.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9697240.1"
                     /translation="MESKFFNWYTQSLGGTFGIISCICAYLNGYMFVYTNSASKYFES
                     IGFLGIISSYTLLPLCMLTLIFGVIYSYTPETSDKSIFNIPFFTLNKRLILITVVFGF
                     IGARVYFIIPAILITFNLYSNVLIAKLKYILCKNKENDTNLKESEV"
     gene            46104..46382
                     /locus_tag="ACGI5H_001531"
     CDS             46104..46382
                     /locus_tag="ACGI5H_001531"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424072.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9697241.1"
                     /translation="MVDTLEFGLKILFFILSIIWMGKIMILRTDKQIVINPLLIGISA
                     ILVMLHTSQSNIEFFGLDVQYIRIVLYIIYSLIILIGIWATNRRNGIF"
     gene            complement(46511..47242)
                     /locus_tag="ACGI5H_001532"
     CDS             complement(46511..47242)
                     /locus_tag="ACGI5H_001532"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905630.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9697242.1"
                     /translation="MNLANLIPFIISAAALSPINSNDKVLSENQLKDIFPDANLRAVV
                     KRYINPDEMTISNIKALDGEFYATGESISNLKGISYLENVDNFIFWNNNIKEVPKEAL
                     SLKDMDSINLANNYLIDDDVVNSLSHNGVDVNCDLNFIDTKDNQYKLDSKYHNVDIAK
                     GESIDLRKIITKKIDSYYKYWEVTDNLPKDLNFIVSVSDKSVLSCEDMIIKGNKTGKA
                     VVKVILSDKNDLNTSQEVLITVNVK"
     gene            complement(47386..48030)
                     /gene="trmB"
                     /locus_tag="ACGI5H_001533"
     CDS             complement(47386..48030)
                     /gene="trmB"
                     /locus_tag="ACGI5H_001533"
                     /EC_number="2.1.1.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889910.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008176 - tRNA
                     (guanine(46)-N7)-methyltransferase activity [Evidence
                     IEA];
                     GO_process: GO:0006400 - tRNA modification [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (guanosine(46)-N7)-methyltransferase TrmB"
                     /protein_id="HFG9697243.1"
                     /translation="MRRRRKKGADEKLLSYTKYVLRDDIDKLKGKWNLKFRNDNPIHV
                     EFGTGKGKFITTLAKQNPDINYIAMELKEEVLLKAVEKADASNLNNILFLWGDVSNIL
                     DYFEAKELSRIYINFCDPWPKNRWSKRRLTHSGFLEMYNRVLEDDGEIHFKTDNEKLF
                     EFSLNEIAANNWLLKNISLDLGNSEYENNVTTEYEDKFMSQGMRIFRCEAKKRN"
     gene            complement(48168..48488)
                     /locus_tag="ACGI5H_001534"
     CDS             complement(48168..48488)
                     /locus_tag="ACGI5H_001534"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424083.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fe-S cluster assembly protein HesB"
                     /protein_id="HFG9697244.1"
                     /translation="MKITLPETAIDTLKSILKDNQDKPNNIRVYFAGVGCGGPSFGLA
                     LDEKKEDDLTYEVGELQFVMSSDEYSQYGDIIIEDTGFGFRVIPENMKDQGGGGCSGC
                     SGCH"
BASE COUNT        18448 a         6428 c         7422 g        16456 t
ORIGIN      
        1 tagaaacttt tattatttta tataaaagtg ataaaaactt atattttgta tttaatagag
       61 tgttgctaag tgaatatatt taaaatggag gaaactttat gaaacaaaat aaatatgatg
      121 atgatagatt ttttaataaa tacagtaaaa tggaacgttc tacaaatgga ttagcaggtg
      181 ctggagagtg gcatgtttta aaaaaaatgt tacctgattt caaaggaaaa agagttttag
      241 atttaggatg tggatttgga tggcattgtc aatatgcagt tgagaatgga gcaatttctg
      301 ctgttggagt tgatatttca gaaaaaatgt taaaagaagc tagaaacaaa acgcaacttg
      361 ataatataaa ttacatatgt atgcctattg aagatattaa ttttccaaaa gatagttttg
      421 atgtagttat tagttccttg gcatttcatt atattcaatc atttgaagat atatgtaaga
      481 atataagtaa ttgtctttca aataaaggta attttgtatt ttctgttgaa catcctatat
      541 ttactgcata tggaagtcaa gagtggtact gtgataaaga tggcactaat ctacactggc
      601 cagtagatgg atattttgaa gaaggagtac gtaagtcaaa ttttctagga gaagaggtta
      661 taaaatatca taaaacatta acaacttatt taaatacgtt aatgaaaaca ggatttgaaa
      721 tattagaaat tattgaacct caaccagaag aaaaactgtt agatacaatt cctgatatga
      781 aagatgagct acgtagacct atgatgttac ttgtatctgc aaaaaaaaga taagtaaata
      841 taaataatca ttattgtaga aaaaaagttg tagaaaataa ttacactaat ggagatgatt
      901 ataccagtgg tattaattac accagtagta aggaggcaaa agcattcgtt gcttttgcca
      961 ttttttaagt tgcaattata cttctacgta gtatatttcg tttccatttt cttctataag
     1021 ctttttcata tcttcaaatt ttaaaaatac agtagcagta ttatcatttg gatgtatacc
     1081 tattttatcc atttttaata aatctttatc aaatacaact tttacaacag cctctttatc
     1141 atttaatata ccaaaaggag tcacagctcc tttagtaagt ttcaagtatt tttgaagtct
     1201 ttcttccgat gcaaaactaa gaggtttact atcaatttgt tgacgaatat cttttaaatc
     1261 tgcttttttg tctttaccta atacaactaa aaaatgttct tttcctttag catcacgaag
     1321 aaataggttt tttacaacaa attccatatg taatgttttt aattcttcca tttcttcaat
     1381 tgtataaact ggtggatgat ttacagcctc ataaggtatg cttaactcat ctaatttttt
     1441 atatacttcc tgttgttgat tgttcatgat ttcctcccat tagaaattta ttttatatat
     1501 aaataatatt atcacagaaa actttaaaag aaaacgtttt atataatata gacaatagat
     1561 tatattttta taaagaagca agaatactca ataaaactta aagaaattaa acaatttcta
     1621 aaaatacctt gaaaatagaa ccttatttgc catttataaa ttatataaaa agggattata
     1681 taaagtcata tatgaaaaaa ctatattata ctatcttttc tttttggaat aaactatact
     1741 ttaaatatag atatttaatt taaataaatt ttacagtatt aatagtaaat tatcttagaa
     1801 aggaatgtgc tttatatgtc tacagacaaa gttgttggaa tcatagatga agaaacggca
     1861 gaacttgcag gaattgaata tactggtaaa atttatgctt cttctggtgt tataaaacat
     1921 ataaagaaaa aacatagatg tcaactgagt aaggatattt ttaatgatat aatagacact
     1981 ataaaaatgg tattaaagtc acctgaatat ataggaagtc atcctaaaaa acctggaaaa
     2041 agtgtggagt ttataaaaaa aattgatgat tatattttag tagctacaga attagataca
     2101 aaaaaaggat atttatatgt atcttcaatg tatgctataa aagaagcaaa attagaaagt
     2161 agagtaaaca gtggaagagt aaaacaatat aatggttaac ataatattat taattttccc
     2221 taaaatattg aaaaatatta ttatataagt tataatatta atatacacgt agatatttat
     2281 tagttagatt tgaggttgga aaaggcaccc aatacgctac tatagagtag ttaatagaga
     2341 tgcaggatac gccgccctgc caaatctaat taaattaaaa agagaggatt aattcctctc
     2401 ttattgtttt tttgagatac taatttaatc tataatagaa agattgaagg tcgtttatac
     2461 aaaaaaattt tcagttatat acattaaact aattaaataa gatatttata atctatatgt
     2521 gatacatatt atatattaat aaaagaaaaa tatatagaaa atccttataa aaatttaaat
     2581 tgtaatgaat aggaagtaat taaaaagaat ttttattgat ttttaaaaat ttagttagaa
     2641 actatatcat tatggtaaaa aatgtattat aatgtttaga aatattataa taaggagcga
     2701 ttaaacatga atctatcgaa gaaaatagaa gataaaagaa aagctaaaca gagagctgaa
     2761 aaagttaaga aagctaaaat tgctacagct ggtgtggtat taggagctgt tactggtgca
     2821 gtgagtggag tacttttggc tcctaaatct ggaaaagaaa caagagagga tataaaagat
     2881 gcttcacaac aaattgctga aaagataaat atgaaaactg tagatgtaaa aggcaaagta
     2941 tctgagaagc tagaggataa aaaaggaaac tttatagaat caaagaaaaa aataaaaaaa
     3001 tatatagata acaaaaagag tgttgaaaat tctagtgagg aagataaaat aatagatata
     3061 gttgaaccag ttagtgttac tgaggaataa tatggacaat acaataacga ttaacataag
     3121 tataatatat gtattattag ctatacttgc ttgtattgct ttagtttatt taattattgt
     3181 acttgttaaa ctacataaga ttttaaataa tgttggaact atgttaaatg aaaatactca
     3241 aaatataaat acaactttaa ataatcttcc taatgttgta gaaacttttg gagaagtagg
     3301 agaaaatatg aaagatgtaa cagaagtagt tactgaagtt acagcagatt ttcttgttac
     3361 taaagacagt gtcaaatcaa atatggatgt tatagttgat atattgacta taattaaaaa
     3421 catttttcta gataaaaaat aataagttta attaaaataa gcctataaga tataatttaa
     3481 acgaccttaa aatagcattt ataaggtcgt tttttattag cttgatttga cactatgtgt
     3541 ttttaataat tggtaatatt cctctttatc atttgaacat atatatctat gcttgttgtt
     3601 tcaattacat ccataagaac atctttacat tcaagctcaa aatcttccat tccttctaaa
     3661 tattcatcat cttcatcaaa aaagatataa gaattatata gccattcttc aaatttttct
     3721 tcaagtatat cccaatacga actccaaaat aatccacaac ctgatatata agatgctcta
     3781 ctttgattta tataaacctc ctctagaagc ttttgtaatc tactgctata aagaaaatct
     3841 gctcttccac tgcttgatat taattcattt aaatcttcta ttgacattaa ttcaacttta
     3901 ccacttttat cataaggagt ataattttca tcaacccatt tatgtggttt gttttctctg
     3961 catactgttg ctatcaactc tacaactttt gttcttatca tttttttatc ctaacttatt
     4021 tattttttat aaaataatca tgattttata atttatctat ttcttgtaat gctaatttaa
     4081 cagtttcata tctatcagca ccatttatta ctacatcacc ttttacaagt ttattagctt
     4141 ctccacctac aacataaacc tttttaccta aaccttgctt ataactagac gcttcaatta
     4201 ttaaagaatc tttcaattgc caatgtaaaa tctgagcagc cactttatca gcatcacctg
     4261 tataaacgat tacattttca tacactttat tttcccctcc ctcttgagaa tttgatatag
     4321 atttgtttag tataccttct gctatcaatt tagcaacttt atctttatta ttaacataat
     4381 aatctgtatc tgctttacta tctacaaaac atacttctat taatattgct ggtgcaatag
     4441 tatgattaag ccaataaaga cctctaacat cagactttgc gcccctatct ttgaatactg
     4501 tagctaacct agtattcact ctttctgcat aggttttgcc attattagtc ttatatattg
     4561 tttctgtccc tactggagtt gaagttgtgg catttgaatt aaaatgaatc tgaacagcca
     4621 aatcagtttc ctgtttattt gctatagcac attggtctgc taaatgatta cttgattcat
     4681 caactcttcc tgtataaaca gtagctccac ctattttaag ccatttaaca attaagtcat
     4741 tcagtattct tgtttctttg ctttcgttta tatacccaac agctcctgta ccttttccaa
     4801 ttaaagtgtg ccctggtatt attactactt tcaaactaac atctccttta caattaaatt
     4861 taacttctat ttaatatatg cataacctag aattttgttt ctttttatat cttatacttt
     4921 tattataacc cattttgtaa aaatatagaa tattaagtaa ataatgttaa aattataatt
     4981 ttgtatataa gacattactt gattgcaata attttatagc atattcatct attctatatc
     5041 cagttctata atatatatgt ttaattccag cttgaattat agccttagta caatttaagc
     5101 aaggaaagtg agttacataa atagagcaat ttttaactga aataccttct tttgcacaat
     5161 aataaagggc attttgttca gcgtgaatgg ttctaataca atgtccatct ctcatttcat
     5221 gaccaacttc actacaatgc ttatctccag aaatactacc attatatcca gtagacacta
     5281 ttctgttttc tgaattgaca attatagctc ctacataagc tctatcacaa gttcctcttt
     5341 cagctactgt ttcgcacagt ctcataaaat attcttgcca tgagcatcta ttttcaagtt
     5401 ttttattcaa attatatacc tccaaaactt atatctaata tataagattt ataccttaaa
     5461 aataatatta aaaacaaatt tatacgataa ataaaattta ttaatactgt ttttagtcta
     5521 aattatttca ttttaaatta aagttacaag gaatctaaaa ttatatatat ctttcttcgt
     5581 aatattaatg ttacaatata aaaaactgtc tcaataaaat agagacagtt ttacagtcaa
     5641 agtttataat acaagttcat atttttcttt aaattctttt acagcttcgg gccatgcctt
     5701 ttgttctgta ataccttttt ctttagctat tttaattgca atctctctta tcattgcagc
     5761 gccttctaat attcccattt ttaatctccc ttcaaatatc tttttgtata gaatataaat
     5821 agtgctaaga tttattacat gctgcatata caatatctat acaacacata acttgtaaat
     5881 tccttttatt ttcatacgtc tttaaccgac atataattat attcaataag ttttaaaatt
     5941 atgaactcaa ttataattat ttttattttt ttagaatcta aacactaaaa attgtaggta
     6001 aatttgtctt atgcctttat aaatatttct acagttttaa ttactggaca tatctatttt
     6061 tattataaaa agcgattaaa aatcgagaat atccgcataa aaactgtata taagcaaaac
     6121 ggttaaagga aaaagaagaa atttacttga atgttaaaat gcgttgcttg aagcaatggg
     6181 cagttttgcc tataatatcg gtaacaactg aaagaaaggt ggttagccct aatgttaagc
     6241 gaaaacatta aaacaatcag gaagtcaaaa ggactttcac aacaagaact tgctataaaa
     6301 ctgaatgtag tgcgacaaac aatatctaaa tgggaacaag gactgtcagt tcccgattct
     6361 gatatgttga tttccatatc agaggtgctt gaaacgcccg taagtacttt acttggagaa
     6421 actattgttg agtcggaagt tgataactta aaagtgattt ctgaaaaatt agagattata
     6481 aacttgcaac ttgcacaaag aaaaaacatg agaagaaaaa tgtttcattg gttatttatt
     6541 ttattatgtg cagtcatatt aatagttttt gtggtcttag ggggactaaa tagtccttac
     6601 ttggattgga attataccga ccctgaaacc gctgtttttg gagtagcttt tcatgctttt
     6661 gagtggctat ttgtcagatt agtaccgatt gtccttatag gagcaattat tggaatcttt
     6721 ttgacacgta agaaaatatg aagtaactct gctttttata atacagcaag cgttccttaa
     6781 aagcgtcatt ctacatggca atcgaggacg actatgtaag gaagaacctt tttgatttcc
     6841 aactaagcga agttattgag gacgacagta agaccaaaac cgcattaagt aaagtacagg
     6901 aagcaagact gctggactta tactctcatg cgtcagatgc aggaaatgcg aggtctggta
     6961 gcatgattta caacgatttg tacaacgact gctagtagaa ataatatgga gataagtatt
     7021 atctacaaag tcagaaaaga aatgacttga taatttactc atgttataat tattgatgtg
     7081 aaattaataa atcgaaattc cttttttgga tttaataata ctgagtaagg aaaaagtgaa
     7141 ttacttttgc aaggaggtgt taatatcagg caagtaaagt cttttgtttt tccagttata
     7201 tccttaatat tcttagacca aattagcaaa gttcttatag gattattctt aatggacttt
     7261 gaaattgata taattgggaa atttttaaga ttcaatcctg ttcaaaatac aaatctctct
     7321 tatgggggaa actttattgg tattctatct aatttatggg tattggtatt gtttaacatt
     7381 ttagttatat tagttattat atctggatat gctttttata aatcaaaaaa tgaacaaaca
     7441 agctattcag taaaagtaat tatgtcttgt ggacttgctg gtacaatatg tagcttgata
     7501 gataaattat tttggggagg aagtttagat tttttgcaga taccaagctt ttttattttc
     7561 gacttaaaag actgctacct tactgttgca gaaataatat ttgttgtcat aggaattttg
     7621 cataatagag aaatatcaat gaaagaatac atatattttt gctatcgtca gtttaaaaaa
     7681 taaatttaga agataaattt aagtttcaag gtaaacttat ttaatcacag caaatagttg
     7741 gcttacttaa gcttttgggc taaactgtga gcactaatta agtctctgat atctaacaaa
     7801 cggagcacaa aaataaaaat taaatataaa gcacagttaa ttttgattaa aaagttgact
     7861 gtcttttctt ttgtagaaat ttaagcatag gtaataaaga aatgactgca tttaagcatt
     7921 atgtatataa ttggaggcaa taaaaagcca gcaaagccca taaaatagag ctgtgctagc
     7981 aacatgatga attataagaa gataatcaaa aacttacgct ttattttaat ttaaaaaaat
     8041 gattactgta aagaaatcat tttttattat aatcactgat acatcaaata ttctaaataa
     8101 aatttttatt tatctggaat tgtatatttt ttctataata ttaactacag cgtacattgc
     8161 ccaagcacag atagccaata caaatactcc catcattact aaatctaatt taaatacttg
     8221 agaaccatat actatcaagt agcctattcc atatcttgaa actaaaaatt ctccaactat
     8281 tacacctacc catgccatac caatattaat tttagttaaa tttattaaat ttcctgtgtt
     8341 tgcaggtaat atgagtttaa ataatatttg agatttagta gctccaaaac tttttaacat
     8401 cttaattttt tcttcatcta tattcataaa ataattataa gctgaaagta tagtaacaac
     8461 aacagaaatc gttacagctg ttacgacgat tccttctatt ccagcaccta cccaaactat
     8521 aattatagga gctaaagcag tcttaggaag agcatttaaa actaccaaaa atgggtctaa
     8581 tatttttgat aatttttctg accaccaaag agcaattgct accaaaatac ctaatacagt
     8641 acctataaca agaccaagaa cagtttcata tacagatatt ccaatatgtt taaataattg
     8701 accactaaat gcatattgaa taaataaatt gtaaatatca cttggtttgc taaatagaaa
     8761 tgtatttata acatttaagt cagctaaaag ttcccagatt acaataaaac caattaaaat
     8821 taatagctgg tagaataata catttctttt ttctcttttt acacctttaa catagtttat
     8881 atatccttca gatcttttat taagcctcat gtgtatctag ctccttccat aatatgtcga
     8941 aatacttttg aaaatcagga actttacgtg ttttgagagg cgtttttgtt ccatccatgt
     9001 taagttcaat atcgtaaata ttttttatgg tagctggtct tttagatagt attgcaacct
     9061 tatctgatat gcttattgct tctgctatag ctaaaaaagt gcaactaatt gcttaaagaa
     9121 acagaattat caacttcagc acccatataa acaatattaa gatttcctaa actgctatcc
     9181 caaacgatac tattaataat agtagataat aacaatctct tatcatctaa actggcatta
     9241 tcaacttcat cattaaatct cttcaaatta ctaacaataa tatcaatatt aatactgtca
     9301 ctactaatat tgatgttact agattccaaa gtattaatct tatcctttaa aatactaatc
     9361 tcattattta ggctctcaat ctgggaaact atataatcag aagcagtact accagtattt
     9421 tttgcaagct ctataactaa atttttaata agtctttcct tatctaaaat ttgattttta
     9481 agtaaattag tctcagattt aaaaatatta aaaacattat cagtcttaat gttattacta
     9541 ttgaatgcac ttataataga ctcttcttta caattcttaa ttttatctat aactaaactt
     9601 tcaactaatg gaccattaag atttttacag ttgcaactat cagacccaag tgttttttta
     9661 gtaccacaaa tataataata ctttaaatcc ttgtcagttt ttttgccttt ataggtaatt
     9721 ctcatattag aaccacattt accacatttt ataagaccag ataaaagagc agtttttcca
     9781 gttgatatcc ttggagtttt atcacgattt ttatctaatt gattttgtac ttcaagccat
     9841 atttcaggtt ctatgactcc atggtgtttt gcaattgctg ctattgagtt agatgtattt
     9901 ttagcatagg taaggattcc acattttcta tctggagtac ctacaacatc cataccacta
     9961 tttttaaggt aatctaaaat ttcatcatta gcttttacat atgctggatt tctaagtatt
    10021 ctagataaag aactagggtc aaatttgcca ccacgaggac cccttattcc attattatag
    10081 acatatttat ataacttaga taaggaccta agttctaaat atttattgta tattagcttt
    10141 acaatctcca tttgttcatc atttacttga agcttataca tacttctttc ttttagattt
    10201 tcatctaaga atgtgatttt ttcactgttg aatccatgag gtgtattgcc tccaagccat
    10261 ctaccactac gggctaattc atacatattg tcttttatac gttctgctat tgtttctctt
    10321 tctaattgag caaatacact tgatataaac atcatagctc ttcccattgg agttgaagta
    10381 tcaaattgtt ctttgataga tataaatgat atgcttagtt catttaattt ttctattaaa
    10441 gtagagaagt cagatacatt tctcgatatc ctatctaatc tataacaaac taggtaacta
    10501 aatttcttat ctttggcatc ctgcatcatt ttcttaaatt gtggtctatc tatattgcta
    10561 ccactaaatc cctcatcttc atatatcaaa aaatctttta caccaataga ctttgcataa
    10621 tcaatacata attgtatttg attttctata gaatcacctt ttccagtaaa tcttgatttt
    10681 cttgaataaa ttgcagcttt caaaattaaa accccctata agttaggata tatatttgaa
    10741 actatttatc tacaaccttt taagtaaact tattagaatg aatttattaa ttaggtaaat
    10801 ttatataatt ctacttttta taatatatga ctatttattt tatttcttta ctattcaagt
    10861 tctaaatcaa taataaattt tgatatttaa ttgtatcagg acaaatctct aatttcatag
    10921 attattaata taaaatcata ggttagtgtg aaaaagttga aatttaaata ttttaaaaga
    10981 taattttttt gaactaatag gtataacaaa aatttatagg gggattgcat atggaaatca
    11041 atgttataga aattttccct aaagataaag ctaaacttaa taaaatagaa atggataaag
    11101 ctagttggtt tgtaaatata ataagtaaaa aatatcctaa agaagcttta aatgaagcat
    11161 ttagtacttt agaaaaagaa ttaaatataa gtaaagctaa tacataagct ttgattattg
    11221 attttatata ctattggttt tatacgctat gacttgacat tatattaatc aaatagtata
    11281 tttttaaata tagcacaatg aagtgttaaa agagcaatgg agctccatag ataaagtcta
    11341 tggagctttt ttgcgtattt aacttaagga ggataggact ttgaataact ttgagattaa
    11401 aactagaata aaatttggag aaggctcact aaaagctttg caagaattaa aaaacaaaaa
    11461 tgtactaata ataacagacc cttttatggt gaaatcaaaa acaatagata aaataacatc
    11521 taatttaata aactcaacat atcaagtttt tgaagaaata gtaccagacc caccaataga
    11581 agtagtagta gcaggaatag aagcatttaa atctataaat ccagacgtaa taatagcatt
    11641 aggtggtggt tctgcaatag atgcagcaaa atctataatg gacttttcta aaaaaatatt
    11701 aaaaattaac gaagtagagt ttatagcaat accaacaaca agtggaacag gttcagaagt
    11761 aacatcattt gctgtaataa cagatagtca aaaaaaatgt aagtatccat tagtgagtga
    11821 tgatttactt ccagatatgg caatactaga cccagaactt gtaaaaactg taccaaattt
    11881 tataacagca gatacaggga tggatgtatt gacacatgct atagaagctt acgtatctac
    11941 aaattctaat gacttttcag atgcactagc tgaaaaagct ataaagttag tatttaaata
    12001 cttaataaaa gcatataaag atggaaatga catagaagct agagaaaaaa tgcacaatgc
    12061 atcttgttta gcaggtatgg catttaacca agcatcactt ggcataaatc attctattgc
    12121 acatgtatta ggtggaaaat tccatatacc acatggaaga acaaactcta tattacttcc
    12181 tcatgtaata gaatataatt catcaatagt aggatatact aacacaactt actctgctac
    12241 agctaaaaaa tatgcacaaa tagcagaatt agtaggactt gggagtgcta atataagaat
    12301 atctgttaga aatttagtaa atgaaataaa gaaactacaa aaagaaatga atatgccaac
    12361 taaattgaca caatgcaaat taagtttaga agatataact aatgaagaaa gagaaatagc
    12421 aaaacttgct ataaaagata cttgtacatt aactaatcct aaggtaccaa ctgaagatga
    12481 tataataaac atattaaaga acattaaata actacatttt attacatgta aatataatat
    12541 tatacaaata gggaaaatgt ttttaaaaat ataaattata tattgacaaa tataaaacat
    12601 aaaactataa tgaaagtatc acaaaggcgt gatactttag tagaaagcaa tggagcttct
    12661 taggaatatt aatattattc ttatggagct ccttttattt taatcaaata gctttttaat
    12721 aaactatatt caaagaaagc agggaataaa tttgactgaa gaatctaagc aaagagttat
    12781 tcaagaatat gttcctggaa aacaggttac attagcacat atcatagcta accctaatga
    12841 agatatatat aagaagttag gattagtact tgataaaaaa gatgcaatag gaatacttac
    12901 aataacacca agtgaagcgt caataatagc agcagatgtt gctacaaagg cttcaaatgt
    12961 atctttaggt tttatagata gatttagtgg ttcagtagta atatcaggtg atgtaagttc
    13021 tgtagaatca gcgttaaatg atgttttaga agtcttagga aatatgttaa acttctcatc
    13081 tacaaaaatc acaaggacat aataatacaa tgaagaatat aatatttatg ggaaagacag
    13141 gtagtggtaa aactacctta tgtcaaaaac tagaccagtt agaattaaag tataaaaaaa
    13201 ctcaatcagt ggaactttat aataatgcaa tagacactcc tggtgagtat atggaaaata
    13261 gaaacctata taatgcctta ataacaacat cagcagatgc taaaattata gcaatagtgt
    13321 atgatgccac acaagaagaa aattatatag caccaggttt tgccagtatg ttttgcaaag
    13381 acgtaatagg aattataact aaaataaata aagctactga aaacgaagtc aatatagctt
    13441 atgaaagact atcactagca ggagcaagtc aaatctttaa aatagacaca gttgataata
    13501 ttggacttga aaaattattt aaatatctag aaaaatataa aaatatagat gaagtttaag
    13561 gggaaatatt tttttattca aaaatattat taaagtatga taaaataaaa aaatgtataa
    13621 actattttaa gaagatttaa tctttaagcg aggtaggaac atggggaaaa aaatactatt
    13681 ggttgatgat gaaccactgt taaggatgga tacaaaagat atattagaaa gtcatggcta
    13741 tgaaataata ggcgaagcaa gtgatggatt tgaagctgtt gaaatgtgta aaaaacacaa
    13801 acctgattta gttataatgg atatagagat gccaatactt gatggtataa aggcaggcaa
    13861 aataatatgt aaagaaaata tagctggtgg agtactttta ttaacttcat ttgaagataa
    13921 agaatacgta gaaaaggcta aaagtatagg tgcttatgga tatttagtaa aaacagcaag
    13981 tgaaaaatca cttatcccaa ccatagaaat gtgtttaaat aaggtaaatg aatttgaaaa
    14041 aatgaaaaaa gatttagaaa aagtaaattc taaattgaat gaaagaaaat tagtagaaag
    14101 agcaaaaggt atacttataa gagagtttaa gatttctgag gatgaagcat acactagaat
    14161 aagaaaatta agtatggata aaagaactac aatgatggaa attgccaaaa tgattataat
    14221 aggatacgat gactaatacg ataaaaaaaa tatcaactgc acaaacatac ttaaataata
    14281 acgaaattga aaaaattata gaagtatcaa aatccttaga tttaatggct tctttttatg
    14341 aagctgatgt ttttatagat gtactaagta aatttgatga tgaagcaatt gttgtggcac
    14401 atggtagacc taaagaaaag tcaatgtact gtgaaaatgt tataggtaaa aaggctttaa
    14461 ttgaaaatga accaggagtt ataaagtgct taaaaacagg agaaagagta agagatatta
    14521 aagctttaac acaggaatat aaactggtca aacaaaatat tcagccaata acactagatg
    14581 acaaagtttt agcagtacta atagttgaaa aagatataag tagtgaagtt aagaatgagt
    14641 ttaatgctag tgaagacgaa gaaaataaaa atttacatca gtttataaaa cttattggaa
    14701 ataatgactt tttagttgat aatttaaatt cagccatatt aatatttgat aaaaatggaa
    14761 aattaaaaat taaaaatcgt attgcaactg agatatacaa aaatcttggg tttggatatg
    14821 atatacaaga tatgcattac aatgatttag atatagaaac caacaccttt gaaaatatat
    14881 taatggatga aaattatgat gagacaaatg aagtttcaat aggtaatatg ttttttaaaa
    14941 taaagaccat atacatcaaa gatgatgaat ttaaggtttg caaaatagta caagatataa
    15001 gtgatttaaa gagaaaagaa gaagaattag ttttgaaaac agtggctata agagaagctc
    15061 atcatagagt aaaaaataat cttcatacag taatatctat aataaaaaaa caaagtagat
    15121 tatctcaaaa tgatgaagta aagcagtgtt tagataacat aataaatagg gtatttgcaa
    15181 tactttcgac tcattattta ctatctaaag aagttgataa taatatatct atacgagaag
    15241 gtatcaattt attagtgtca aatattcaag gtggctattt atttagtaag gatatagata
    15301 tacgtataac tggtgaagat tttaaaatta gtggagaaaa agcaacagca atacttttgg
    15361 ttataaatga aatactacaa aattgttatg accatgcatt ttcggataga gaacatggta
    15421 ctatacaaat attaataaat aaagataacg actatagaaa tattgctatt atagatgatg
    15481 gaattggatt tgatagtaat aatataaata aaaatagctt agggacatat ataatagata
    15541 gttatataac acagatgtta aaaggaaata tagagagaaa aagtagtgag aatggtacag
    15601 aagtattaat tactatacct acacaaatta atatttaaat aataactcat ctacaaagta
    15661 gtagttttaa ttgagcaaag aggcttaagg ttattaatag attaagttaa ttgaatgtat
    15721 ttataaaaat tataagtata tattcaattt aacaggtatt tattataact ttaagcctct
    15781 ttgcttgttt aagacatact taaattttag gaggtgagaa aatgagagaa gagttattaa
    15841 gtgttggtat tgacattgga acaagtacta ctcagttaat tttttctaaa ttaatagtag
    15901 aaaatactga atcaaatttt tcggtaccta gaataagtat agtagacaaa gaaattattt
    15961 ataaaagcaa agtttatttc acccctctta tttcaaataa tgaaataaat ggtcaacaaa
    16021 taaaagatat agttgaaaat gaatataaaa aagcaaatat atctaaagaa gatatacata
    16081 caggagcagt aataataact ggtgaaacag ctagaaaaga aaatgcaaat gatgtacttc
    16141 atactttgag tggatttgct ggggacttcg ttgttgcaac agcaggacct gatttagaaa
    16201 gtataatatc aggaaaagga gctggagctc atatttattc aaaagaacat tcaactacaa
    16261 ttgtaaatat agacataggt gggggaacta gtaacatagc ctcatttaaa aggggagaag
    16321 taaccgatac tgggtgtttg gatataggtg gaaggcttgt aaagatagat aaaataagta
    16381 aaaaaataac ttatatatca cctaaaatag ataaaatcat aaaagataat aatttaaatc
    16441 ttcaagtagg cacaatggct actgtagaaa atacaaagcc aatagtggat ataatggttg
    16501 acttattaat ggaaagcata ggattaaaga aacagacacc tttgtttgat tttataataa
    16561 ccaataaatc aataagtata gatgaaaata ttaaaaatgt ttcattctct ggtggagtag
    16621 ctgattatat ttactatgat ggagaaataa aagattattt tgaatatggt gacttgggaa
    16681 ttttacttgg gcaagcaata aaaaattgtg aataccttaa aaaagtaaat gtagttaaat
    16741 ctatggaaac aataagagcc acagtggttg gagcaggttc tcatactact gaagtaagtg
    16801 gaagtacaat aacttacact agcgaaaagt ttccacttaa gaacttgcca gttttaaaat
    16861 tatcaattga tgaagaaaca ggcacttcaa aacaaatcag tgaagctata aaaaataaac
    16921 ttaattggtt taaactagaa aatgatttac agaaagttgc tatagccatg ataggaaaga
    16981 aaaatccaac ctttttagat atacaagagt atgctaaagg gtttgtagat ggaatgcaac
    17041 aaatcataga aaatgattta ccttttatag taattgttga aaatgatatg gcaaaagtgt
    17101 taggtcaagc aatatatgca ttattaaatt atgaaaaaga aattgtttgt atagacagtg
    17161 tcaaggttga aaatggagac tatatcgaca ttggaaaacc tatagttgaa ggtaaagttt
    17221 tacctgtggt aataaaaaca ttagttttta attaatagaa ggaggtaagt aaatgatttt
    17281 aaatacaaaa ttatttggac gtacttatca gtttaaaggc ttatatgatg taatggctaa
    17341 agctaatgaa gaaaaatcag gagataaatt agcaggtctt gcagcagaat cagctgaaga
    17401 aagaatagca gcaaaagttg ttttatcaca cataaaattg gaggatataa gaaataatcc
    17461 tgcagtggca tatgaagaag atgaagtaac aagaataata caagatgctg taaatgaaaa
    17521 agtttatgaa gaaataaaaa attggacagt ctctgaactt agagaatggc tattggattc
    17581 aaatactaca agtcttgata taagaagaat atcaagagga ttaacttctg aaatgatagc
    17641 agcagttgca aaattaatgt caaatatgga cttagtttat gcagctaaaa agataaaggt
    17701 tactgctcac tgtaatacaa ctataggaga acaaggaaca ttatcagcaa gacttcaacc
    17761 taatcatcca acagacgacc cagatggaat acttgcatca cttcttgaag gtttaacttt
    17821 tggtatagga gatgcagtac ttggattaaa tccagttgat gactctgttg agagtgttac
    17881 taaagtatta aaaagatttg aagaagtaaa acaaaaatat caaataccaa ctcaaacatg
    17941 tgtattggca cacgttacta cacaaatgga agcaataaga aatggtgctc ctgcagattt
    18001 aatattccaa tctatagcag gttctgaaaa aggaaatgaa gcatttggat ttaatggcga
    18061 cactatagaa gaagctagac agttagcctt aaaacacggt acagctacag gacctaacgt
    18121 tatgtatttt gaaactggac aaggttcaga attatcttca gaagcacatc atggaataga
    18181 ccaagttact atggaagcta gatgctatgg atttgctaaa aagtatgaac cattcttagt
    18241 aaatacagtt gttgggttta taggacctga gtacttatat gatgctagag aagttgtaag
    18301 agcaggactt gaagaccact ttatgggtaa actacatggc ttaccaatgg gtgttgatgt
    18361 ttgttacact aaccatatga aggctgacca aaatgatatg gaaaacttag ccatactatt
    18421 aacaacagca ggatgtacgt attttatggg aatacctcat ggagatgatg ttatgcttaa
    18481 ctatcaaaca acaggatacc atgaaacagc atcacttaga gaaatgtttg gactaacagc
    18541 aataaaagaa tttgatgctt ggatggaaaa gatgggattc tctaaagatg gtaagttaac
    18601 agagttggcg ggagacgcat ctgtattatt aggataggag gtatttaata tgaatgagaa
    18661 ggatttaaaa gcattggtag aacaattagt tggacaaatg gttggagaat tagatactaa
    18721 tgttgtgtct gagactgtta aaaaggcaac tgaagttgta gtagacaaca atgcttgtat
    18781 agatgatata acagaagttg atataagaaa gcaattacta gtaaaaaatc ctaaggatgc
    18841 agaagcttat ttagatatga aagcaaaaac acctgcaaga ttaggtatag gaagagctgg
    18901 tactagatat aaaacagaaa cagttttaag atttagagca gaccatgctg ctgcacaaga
    18961 tgctgtattc tcttatgtag atgaagaatt tataaaagaa aataatatgt ttgcagtgga
    19021 aactttatgt aaagataaag atgaatactt aacaagacca gatttgggaa gaaaattttc
    19081 tccagaaact ataaataata taaaatctaa atttggtaca aatcaaaagg ttttaatatt
    19141 agttggagat gggcttagct cagctgcaat agaggcaaat ttaaaagact gtgtgccagc
    19201 tataaaacag gggctaaaaa tgtatggtat agattcaagt gaaattttat ttgttaaaca
    19261 ttgtagagtt ggtgctatgg accacttagg tgaagaatta ggttgtgaag ttatatgtat
    19321 gttggttgga gaaagaccag gattagttac tgctgaatca atgtcagcat atatagctta
    19381 taagccatat ataggaatgg cagaagcaaa aagaacagtt atatcaaata ttcacaaagg
    19441 tggaacaact gcagttgaag caggtgctca tatagctgaa cttataaaaa ctatgttaga
    19501 taaaaaagct tcaggaatag accttaaata aagtcgaggg agtgtagaat atgaaaaatg
    19561 atgtaattcg tcctaatata ctaggaatta aaataatttc aaatataagt ccagaaatgg
    19621 cacaaaaact agaattaaaa tcacatcaca aaagcttagg tttaataact gcagactgtg
    19681 atgatgttac gtatacagct cttgacgaag caactaaagc ttcagaagtt gatgttgtat
    19741 atgcaaaatc aatgtatgca ggtgctgcaa atgcttcaac aaaacttgct ggtgaagtat
    19801 taggaataat agcaggtcca agcccagcag aagtaagaag tggtctaaat gcagtagttg
    19861 attttctaga gtatggagca acttttataa gtgcaaatga tgatgattca atagcatact
    19921 atgctcactg cgtatcaaga acaggtacat acctttcaga ggtagcagga ataagagaag
    19981 gtgaagcatt agcttattta gtagcaccac cacttgaagc aatgtatgca ctagatgcag
    20041 caatgaaagc tgcagatgtt aagatgtgtg aattatttgc acctccaact gaaacaaact
    20101 ttggtggagc attacttaca ggttctcaat cggcttgtaa agcagcatgt gatgcatttg
    20161 cagaagcagt aaaatcagtt gcagacaatc caacaggatt ttaaggatag ttagatggat
    20221 gctataggct taatagaagt aataggatat gttgctgcaa tagaagcttc tgatgcttgt
    20281 ttaaaatctg caaatgttaa tattgtaaga gttgataagg ttggagcagg tattgttact
    20341 ttaacaatat gtggagatgt cggtgctgta aaagctgctt tagaagcagg tgaaatagca
    20401 gcttccagag ttggtacatt aagaacatca catattatac cgagaatcca taatgaagta
    20461 acaaatgctt tattcaaaac taaagaacct aaagtctgtg aagtttcaga agataaagaa
    20521 aaaaactttg agattacatt ggaaatagct gataatgtat cgaaaaattt atcagaaaaa
    20581 gaaaatgtaa ttttagatgt caatgaaaac agtggagata ctgaaaattt atatagtgat
    20641 atagataaaa caaacaaaaa aattgaaaca gttgatgata gtttaacaga agctaatgag
    20701 gaaaaaatag aaaacactaa tgataaagaa gtattggaac aagttaaaat agaaaattcc
    20761 gattttgata gagatgacct atcaaagaac agtgtaaaaa aacttaaagc tatggctaag
    20821 aaattagatt cttcaataac ttataaagac ttaaatgttc ttaaaaaaga agaattaata
    20881 aacttagtta aaaagcttag tagaagggat agatagttat gacactttta gataaagatt
    20941 tagtatctat acaagaagta agaactcttg taagaagatc taaagtggct caagagaaac
    21001 tttctaaaat gagtcaagag caaatagata aaatagtaaa agctgttgta gatgcagcat
    21061 ttaataatgc tactaaatta gctaaaatgg caaatgaaga aactggattt ggaaaatggg
    21121 aagataaagt aattaaaaat acttttgcat ctatgggagt ttatgaaact ttaaagaaca
    21181 caaaaactat tggaataatt ggtgaagata aagaagccaa tacgatagat atagctacac
    21241 cagttggagt tgttgcaggt cttatacctt caacaaaccc aacatcaaca gtaatataca
    21301 aaactataat atctctaaaa gcaggaaata ctatagtttt ctctccacat ccaaatgcaa
    21361 aaaactgcat acttgaaaca gttaatataa taagtgatgc tgctataaag gctggagctc
    21421 cagaggattc aatattatgt ataactaatc caagtatagt tggaaccaat gaattgatga
    21481 aacataaaga tacaaactta atactagcaa ctggaggaga agcaatggtt agagctgctt
    21541 actcttcagg aacaccagct attggagttg gaccaggaaa tggaccagca tttatagata
    21601 aatcagcaaa tgttaaatta gcaatcaaaa gaataataga ttctaaaact tttgataatg
    21661 gtgttatatg tgcatcagaa caatctatag taatagaaaa atctatggaa gaaactgttt
    21721 taaaagagct taaaaatcaa ggtgcatatg ttttaaatga ggaggaaagt gaaagattag
    21781 caaaattcat attaagagct aatggtacta tgaatccaca aatagttggt aaaagtgttg
    21841 aggtaatagc aaatttagca gacttaacaa atgtacctaa aaatacaaaa gttctagttg
    21901 caagagaaaa taaagttggt cacaatgtag cctattcaag agaaaaactt acaccaatac
    21961 tagcgttcta tgttgaagaa aatgtagaag ctattatgaa cagatgcaga gaaatattgt
    22021 taaatgaagg tgcaggtcat acattctcaa tgcatgtaaa tgatgaagaa ttggtaaaaa
    22081 gatttgccct taatatgcca gtatcaagaa tacttgtgaa tactccttca gcacttggag
    22141 gaataggtgc atcaacaaac cttgtaccag cactaacact tggttgtggt gcaataggtg
    22201 gaagttcaac ttcaaacaat ataggaccac ttgatttaat aaatgttaaa agagtagctt
    22261 atggaatcaa agaaatagaa gaacttggaa gagataaatc tcaagttgaa aaatcaatgt
    22321 ttgactcaat ggataaagaa gaattaataa atcttcttgt tcaaaaacta gtcaaagaac
    22381 tagcataact aaaataaaca atgaaactta tggctatcgc tataaatttc taaaaatata
    22441 aactataaaa aactataaaa ttaaattttt ggaggataag attatggcaa gtgcaaacgc
    22501 attaggaatg atagaaacta aaggattagt aggagcaata gaagcagcag atgcaatggt
    22561 taaagctgca aatgtacaat tagtaggaaa agagcaagta ggtggaggat tagttactgt
    22621 aatggtaaga ggagatgttg gagctgttaa agctgctaca gatgcaggag ctgccgctgc
    22681 cgagagagtt ggagaactaa tatcagttca tgttatacca agaccacact ttgaagtaga
    22741 tgctatatta ccaaaggtat cagctgagta atataagaat aattataaaa tttaaatttt
    22801 gattgaaaaa gaggctatct caaaaatgag tcttactaat aaactcaatg tattttgagg
    22861 tagtcttttt tatacatcta ataggagatg tgataaaatg ggtgttttaa cagaaaacga
    22921 agtaaaaaga aaaattggaa aaaacaaaaa taatataact gaattttata tagaaaaagg
    22981 tcaaataata actccttctg caaaatctta tttagctgag agaagtattg agcttaaata
    23041 tgttgataaa ctttcagatg taaacaatga acctaaagaa gttgtaaaag aagtagttaa
    23101 agagaaaaaa tatagatata ctactgtatt tggcgctaaa ttggatgaaa aaccagaaca
    23161 tatgactcaa ttaaatggaa atcttttagt ttttaaagac cataaaagaa taatattgag
    23221 aggaaaaata gattctcttg aatcagaaat actaaaggta cagatacttt gtcagaaact
    23281 agatatgcca aagcttgtta aggaattgca agaagtatta gactttgtaa gaaatataat
    23341 gagatgtgaa gttttagatg aaaagctagg ggactttaaa cttttaggat taactcctca
    23401 agaacttaga gaacaatctc actatcctaa aaaatacttt ggtataggac atgagttccc
    23461 aagttatgaa atgggagaag tagtagtagc tataaatagt ataagaagta atacacgaga
    23521 ggttgaactt gcagcctatg aagcatttaa gggtgagtat ggaaatgttc acagagaaga
    23581 tttaataaag gcacttaata gattatcgtc agtattttgg ataatgatat ataaggttag
    23641 aactaataag tataagtagt tggaggacat aatggagaat ctattaaatg aaatagtgga
    23701 agaagtaata actagagtta aaaaagaagc atttatagaa gttgaagcat caggaagaca
    23761 cgttcactta agtagagaag atgtcgataa attatttgga gaaggatata ctcttacaaa
    23821 actaaaagac ctatctcaac caggtcaata tgcatgtaag gaaagagtta caataactgg
    23881 tcctaaagga agtataaaaa atgtagttgt acttggacca tgtagaaatg aaactcaggt
    23941 agaaatatct ttaacagatg gttcaactct tggactaaaa gctcctataa aacaaagtgg
    24001 agacttagaa ggtactttaa gtattaaaat atcaacacaa tatggtgaag ttgaacttga
    24061 taaggggtta atggttgcta aaagacatat acacatgact cataaagatg ctgaaaaatt
    24121 caatgtatgt gataaagaga tagttgaagc taaggtgatg ggtcaaagac ctttaacatt
    24181 tgatgatgta gtaataagag tgagtgacag ttttaaaact tatatgcata tagactatga
    24241 tgaagccaat gcatgtggtt attcaaaagg aactgttgct aaaataataa agaaagcgta
    24301 aatttaacct actatataaa ttacctctag ggaggattta atatgaatta tgataacctt
    24361 gtagatttaa taacggaaga aatctataaa aaaataaata gtaatgaaat aaaaatatct
    24421 aataaaccta aagctgtgat tgtatttgaa caagataaca ataaatttaa cttattaaaa
    24481 gatgaatttg aaatagtaga atttgataaa agtataaggg aatgtgaaat agtgatagtt
    24541 tcaagacttt gtatgagggg gctatcgaat atagcacttg gaaattcaac aagtgatgaa
    24601 gaaagattta tactaaaaat gattatgaag ggcaaagaag tatatgtcct agatgaagga
    24661 attgaataca aaaaatataa ggatactgca ccaaaagcat tatataagaa atttatgtca
    24721 tttgaagatg aaatatgtaa atttggtgta gaaattataa aagacttaaa tgttataact
    24781 aaaaataagt taaatataaa gaaagaacta gaaagtacta gaggttctaa aaaagaagat
    24841 acaaaagttt tagataaaga tgttttaaat ttaaccagtg tagaaagtgt aaaaatagat
    24901 aatgaattta gtttagattt aaggaataaa aaacttatat cggaagctga cttaagaaaa
    24961 ccaactataa atggagttaa aaacatatta gttaataaaa aaagtataat aacaccatta
    25021 gctgtagatt ttatgagaat acaccatctc aaactaaaga aagtgtaagg aggtaatttt
    25081 atggatatag gaaaagttgt aggtaatgtt tgggctacaa gaaaagatga aaaattatgt
    25141 ggccaaaaac ttttagttgt aaaaatttta aaaactaaag acacatacaa ggaaggcttc
    25201 atggttgcag ccgataatgc aggagcagga aatggagact tagttcttat atccaaaggt
    25261 tcctcagcta gagagtcgat tgaaaaatct catgttccgg tagatgcaac tatagttgga
    25321 gtagtcgatt cgtttgaggt gtttgatgaa taaaagtata ggagctatag agtttaaaag
    25381 cattgctaaa ggtatagaag tatccaatga aatgataaag aaatcttcag ttgatgtatt
    25441 gtacttaaaa agtatttgcc caggtaaatt tctaataata gtaggtggag aaacttctta
    25501 tataaatgaa tgtgtagatt atggaataaa acttggagaa ggatatattg tagataactt
    25561 cgtaataaat gcaatttcac aagaaatatt agatggattt aaaaataagt atcaaaagct
    25621 agatagtata gtctctatag gcgttgttga aagtagtaaa gtatgcgctg gaataaaaat
    25681 gcttgataag actttaaaat ctggcgactt agtattagta aaacttcaat tatcttttgc
    25741 tataggtggc aaattagtat atatagtagc aggagattta agtagtttag aatatgcatt
    25801 aaaagaaagt gaaaatgtag taagagaaaa agaagtaata tataagactg taataccatc
    25861 agtagacagt caaataataa aaagtctaat aaaataatgg ggggaattat gagtataaac
    25921 gaaattataa tctatgtaat ggtagtcttc atggtacttg gagctataga taaatgtata
    25981 ggtaacaaat ttggtcttgg agaacaattt gaagaaggta taatggcaat ggggtcactt
    26041 gcagttgcaa tggttggtgt tatatgttta gcaccagttc ttgctgatgt attaagacca
    26101 attgtagtac cagtatttaa tatacttgga gctgacccag ctatgtttgc tggaagttta
    26161 ttagctaatg atatgggtgg tgcaccactt gcacttgaac ttgcgaaaga ccctaatgct
    26221 gggttatttg gtggattaat agtaggggct atgatgggac ctacaatagt atttataata
    26281 ccagttgcgc ttggaataat tgaaaaagaa gaccaaaaat tcttagcaac aggaatactt
    26341 gcaggtataa taacaatacc tattggagca ttcgttggtg gattagttgc aggattcgag
    26401 gtaatgatgg ttcttagaaa cttagtgcca ataataatat ttgcagtagt tatagcactt
    26461 ggattattaa aattcgaaaa tgctatgata aaaggattca catactttgg aaaaggtgta
    26521 gtaatagtta taactttagg acttgctgct gccatagttg aagctttaac aggaatagtt
    26581 gtaatacctg gaatgaaacc aatcagtgaa ggtatagaaa tagttggaga tatagcaata
    26641 gttttagcag gagcattccc attagtgttt gttataacaa aggtatttaa taaaccatta
    26701 atggctttag gaaaagttct tggaatgaat gatgtatcag cagcaggcct tgttgcaagt
    26761 ttagctaact gtataccaat gtttggtatg atgaaagata tggacaatag aggaaaaata
    26821 ataaatgtag cattctctgt atcagcagca ttcgtatttg gagaccactt aggatttacg
    26881 gcaggattta attctaatat gataacacca atgatagttg ctaaattagt tggtggtata
    26941 acagcagtat tgttagctat ggttatcgca aataagacac taaagaagga gaatgtataa
    27001 gatggatata tcaaatatag ataaaaattt aattgaaaca ttagtaagac aaataataga
    27061 agaaaaaata agtggaacta aagacacagt agattttgtt agaaataaag acattagtgg
    27121 aataacttct ataaagttac caactgtaaa agttagtgaa tctgatagat tagatacagg
    27181 gaatccaagt gatgtagttt acacaaaaga tttatttaca ttagaggaaa gcccaagatt
    27241 aggttgtggt atgatggaaa tgaaagaaac aacttttgat tggactctaa actatgatga
    27301 aatagattat gtaatagatg gaactttaga tataataata gatggaagaa aggtttctgc
    27361 ttcttcaggt gaattaatat ttataccaaa aggaagtaag atacaatttt ctgtacctga
    27421 ttatgctaga tttatatatg taacatatcc ggcagattgg gcatctcaaa attaataaaa
    27481 atcaagttaa gttaataata atcaaataaa taatttaaaa tacaaactct taaataagca
    27541 cacatattta aaaaagctat gaattaaaat tcatagcttt ttttataaag aatgttatat
    27601 tttagacgta ttttttctat atttactggg agacatatta tattttttat taaataatct
    27661 aataaaatgc tctacatttg gataaccaat actattttac tgataatctt ttccttatca
    27721 ctaatcttac attttaaaat attattttta ctcgtaatat tatcataaga atttgtttct
    27781 tatttaaaac taattagaat tataaagttt attgccatgt tattaataaa ataaatccag
    27841 ttaaatcgag tgctagttaa agtaataaga aacttttaca atggtttcct ttatcgattg
    27901 aaataaaagt taatatggta taatatctaa agagagaatc ttatcaatta gaatatgcat
    27961 agaaacaagt ggcttaaaag gagacgttat atggaagaga tagtaaagaa ggaacaagca
    28021 agtatgaatg atattttttt gtatcttaaa gctaaatcaa actcattata taaatttgta
    28081 atattatata atgagtttat caataaacct aaagattatg gaactgggga acttataaac
    28141 atggttgaag tacatatgct aacagcgatt gaagaaaatc caggaataag tccaactcag
    28201 ttagctaaaa tatggaacag aactaaaggt gcaatatctc aaactatatc taaattggag
    28261 aaaaagggtt atataactaa agaaaagaaa gaaggaaatg caaaaactat attactatat
    28321 ccaaccacat caggagtaga gttaagtaag gcacataaac tatatgacac catagatgtt
    28381 acaagaacat ttgaatactt aatcaaggag tgtacattag aggagataga tagtttttat
    28441 aaagtaattg atttgtttat taatttatta gaagaatctc cgcaggaaaa taatgattct
    28501 gaaaaagtgt agctgagatt gaagttgaat aaagagaaat agatattata gaagtagtac
    28561 ttaagtacac attatataaa aatataatag gtataggatt aaaaagttta gtggtttaaa
    28621 gtttaatcac taaacttttt taatgtctat aatctactat tatttaattt actaaaaata
    28681 aaaaaactca ttatattaag ataaaaatag aaaaataact agaaaaatac tataatatat
    28741 cagcttaata cagaaaaaag ttaaaaaatt tgagaaaaat aaaaatgaaa acgttttata
    28801 ttgacataga gaaaaagtag tgataccatt taaatatagt ttagtagcta aactatattt
    28861 aaattataat aactatttta gggggatgtt atgaatttaa aacaattaag tgaaaaatac
    28921 gaagaatatg taattcaaat gagaagagaa tttcataagt atccagaatt atcttttaaa
    28981 gaaataagaa caacccaaag aataagggaa gaattacaaa aaataggggt cccttttgta
    29041 tctattgaac caaatatcgt aatagctact atacaaggca aaaatgaagg taagacaatt
    29101 gcaattagag gagatataga tgcgcttcca atgcaagaag attcagatgt tgaatacaaa
    29161 tcagaatatg atggaataat gcattcttgt ggacatgatg ctcatggagc tatgttacta
    29221 ggacttgcac atatgctaaa tgatataaga aaagatttaa aaggtagagt attattagtt
    29281 tttcaagcag ctgaagaagt tggtggtgga cacaaggaga taatacagta ctttaaggaa
    29341 aatggaggac cagatagatt aatagctact catgtttggt ccgatattga agctggtaaa
    29401 atttctgttg aaccaggacc tcgtatggct ggtgggtctg gttggagaat agacataaca
    29461 ggtagaggag gtcatggttc tagaccagat caaagcatag atcctataaa gccagcttgt
    29521 gatatagttt taaaagtatc ttctatacca gttaatcata taagtgtact agaacaatgt
    29581 gttgtacatg catgtgcaat acatggagga actacaatag gaaatgttat tccaaacaat
    29641 gcagaggtaa taggtggata tagatatttt actgaagaat caggcaaaaa agtgtttgac
    29701 attataaagc aaatgagtaa tggtgttgga caagtttatg gagtggatgt gaaggttact
    29761 catactggag gcataggacc tgttatcaat gatgaagaag cagttaagat ggctaaagaa
    29821 atagtttcta atatagatgg attggagtta gattcttatg agccaatatg tgcatcagat
    29881 tgttatggtg aaatattaaa agagtattct ggcttttatt gttatctagg ggtaggtaac
    29941 aaagaaaaag gaataatata tgcacaacac catcctaagt acaatataga tgaagataca
    30001 ttaaagttag gttgcgaatt tatggctaaa tatgcagttg aatttttaaa taaaaataat
    30061 aactaaaata aatcgaattt tataaatggg ggggatgaaa atgcaaggtg cattaaagga
    30121 aaataagaaa aaaagtggtg gaggattttt aggatggatt gaaaaagttg ggaataaaat
    30181 gccacatcct ctagcattat ttacatatat tacattgata gtagtagcat tatctgcaat
    30241 agcaagcttt ttaggttttt cagcaacaag tcctgctaca ggaaagttaa taaaagttat
    30301 gaacttaata agtgcaaaag gtttagtact atttatgcaa gagtttgtta agaacttcca
    30361 aaacttccct gtgcttggag tagttttagt tatggcagtt gccacaggag tttgtgaaaa
    30421 gacaggattt ttttcaactg ccataaaaat gagtttatca aaagttaagg ggaatgcggt
    30481 tgtatttata atagctttta taggagtatt tgctaatcaa gctggtgatg ctgcttttgt
    30541 attagtacca actcttgcag gagcaatatt ttatggatta aatagaaatc cattagctgg
    30601 tatattctgt ggatttgcat cagttggtgg tggatttgca acagctgtaa ttcctggggg
    30661 atgggacgtt acgctaacgc caataactgt atcagctgct caaactattc aacctgcatt
    30721 tgatatgaca ttattagcta gttattatgc actatttgta tctgcgttta tagtagctac
    30781 agtatcaaca atagtaacgg ttaaatttat agaacctaaa ttaggtaagt atactggtaa
    30841 accagaaggt atagatgata atcaaggttt tgaggtcaca aaagaacaag caaaagcagc
    30901 aaagttagca ggttttacag ttttagctta tgtagcgtta ttaattgctt tgtgtatacc
    30961 agctaatagt tttttaagaa gtccagaagg ttctttaata tttggagcac cacttatgtc
    31021 ttgcttacag ttttttatag taatactatt cttcttgcca gggattgtgt atggaatgag
    31081 ggttggtaaa atcaagactg taaaagactt aaatgatata ttatgtcaat caatggcagc
    31141 aatggcaccg tttatcgtac ttgcaatagt tataggtcaa ttcttaacgc tattctcagt
    31201 gtctaattta gcacaggtac tagctataaa aggtggagca ttactcaact cattgccact
    31261 accaccacaa gctataatac tgctattctt agtactagta gcgtttataa atatatttgt
    31321 tataagcgga agtacaaaat ggatgatatt tggaccagta tttgttccaa tgttaatgca
    31381 attaaacata catccagcat ttactcagtt tgtatataga ttaggagatt ctgtaaccaa
    31441 tcatttatca ccattaaatg cattctttat aatactttta gcaacagtcc aaaaatacga
    31501 taaaaatgca ggtatgggaa ctatattctc agctatgata ccttacacta taggttactt
    31561 tgtagtactt gcagttttag tagtagtttg gatgacaata ggtataccag taggaatagg
    31621 tggacaagtt tggttataaa acatatttaa taattttggg aggaaagaaa atggaaacaa
    31681 ctgaaataag atacaatttt gatgaagtaa tagatagaag tggaacaaac tgtcttaaat
    31741 atgatcttaa gagtcaattt atgccagaat ctccagaaga tgcactacca ctatgggtag
    31801 cagatatgga ttttgcatgt gcccctgaga taattaatgc aatgcatgaa agaatagaca
    31861 gaaaaatatt tggatatagc tctcaacaaa ctgatgatta ttatgaagct gtatgtggat
    31921 ggtttaagag aagatttgat tggaaaatag aaaaagagaa tatattcttt agcccagggg
    31981 ttgtgcctgc gttaggattt ttcacacaaa tattaacaca aaagggtgat ggtatcataa
    32041 tagaaaagcc tgtatactat ccttttgaag ataaaataac taataatgaa agaaaagtag
    32101 ttaatagtcc tttaaagttt gaagatggtc attattctat ggattatgat ggatttgaag
    32161 aattagctaa agatgaaaat aataaggtgt ttatattatg tagtcctcat aatccagttg
    32221 gtagagtatg gaaaaaagaa gagcttagaa aaatagtaga catatgtaag aaatatgatt
    32281 tgtggataat atctgatgaa atacattgtg atattattcg taaaggtgaa aagcatatac
    32341 cattagaagt agcatgtcct gattataaag atagaataat aacttgtaca gctccaagta
    32401 agagttttaa cttagctggt atgcaattat caaatatagt aatcaataat aaggaattac
    32461 aaaaaaaatg gatgcttgaa acagattcta aattagctat attcctacct aatccattcg
    32521 caatagttgc tactaaagtt gcttataatg attgtgaaga ttggatgaat caagtaaatg
    32581 agtatataga tggtaatatt aaatatgtag aagattttgt taatgagtat atgcctaaag
    32641 taaagataat aaaatctcaa ggaacttact tagtttggtt agactttaga gggtatggat
    32701 tagatgcaaa acagcttgaa tatgtaatgc ttaacaaggc gaaggtattg ctagatgaag
    32761 gatacatatt cggagaagaa ggagcaggat ttgaaagaat aaatgttgct tcacctagaa
    32821 caattataga agagtgtatg aatagaataa aatgtgcatt tgaaggatta taatagtaat
    32881 atctaaataa tatatttgtg tattttaaaa aaagactatg ctaaaaaaat atttcaaagc
    32941 atagtctttt aaagttttat gatgagttta aaaaatttca aaacgttact attcacttat
    33001 atgtttatat tagaaataat tccacaatat actcattttc taaagttgca cttttataca
    33061 ccttgcttca ccaatatcat gtgtaaccaa aatagtagac ttattctcat tcttaataat
    33121 actataaaca tcatcacaaa ctaataatct agtctgataa tcaagagctg aaaaaggttc
    33181 atctaaaagt agaatatctg gatttacaga aagtgttcta ataagcgcaa ctctttgtct
    33241 catacctcca gataattctt ttggatacat acttctaaaa tcccataatc cataagtctt
    33301 taaaaggctt tcaactctat ctaaagattt tttatctttt ttgccttgaa tttccaatcc
    33361 aatagttata ttatccatta tatttctcca ttcaagcaaa ttatcttttt gaaacatata
    33421 tccaatattt ccagtaatct ttatatcacc actagtcggt tttaaaagat tagtaagaat
    33481 atttaatatt gtagatttac cacttccaga aggaccaagc aaagttaata tttctccttc
    33541 tttcaagtta aaattgacat cctttaatac ttcaagctcg ccttccttag tgtagaagtt
    33601 catatttata tttttaactt ctactatgtt gtcattcatt atgccacccc ctataacttt
    33661 tagctcgtat atattatgtt attaacaata tgacctattt gtaccatttt tcataaatat
    33721 aatataaata ttttgtttat ttacgtattt tcttagtaac ttgtacgtat aaattataga
    33781 taaataaatt ataaggtagg ggataaattt gagtaacata ataacgaatt taatagagtc
    33841 aatatttact aatccaataa ctatattgtt tttacttgca ataactgtgt attctgtttt
    33901 taaaataata gaaaataaca gagtatattc atttgtaagt tcaaaattag acgaaatcaa
    33961 tagagactat aagacaagtg agttttataa aaaggtaagg gatgactact atacatatag
    34021 taaagaaaat ccttatgcag acgtaaatat aacttcattt atagaggaag ttgtatctga
    34081 tttaaagcat aataatttgc cattgttaga aaaaattaga agtataaaaa attcatcttc
    34141 aataagtata ttacttgggg ttttaggtac gtttgttggt ctttctacaa tgcttttatg
    34201 tgttgatact aaagacatta taaattcact tccttcaact attagtagta tgcaaactgc
    34261 atttacaact agtatatttg gagttgtatt ttctctaatt ataggttact ttactaagat
    34321 aaaagattgt gaacatgttt tgatacaaat aatgttaaaa tctgaaaatt tactaacatc
    34381 tgaaataact cattttaagt cagaaagaat ggatttaaaa gtagaagagg taaaaaatac
    34441 aataaaacaa ataagtaagt ctatagaagc tattgaaaaa tttgataaaa tatctaaaga
    34501 tttaaatgac tttaatgatg aatttatcag tggtatagaa gctttaaaaa gccttttaga
    34561 aggttctcaa agttctatta agacatttga ccagagcgta agaaaattag ataaacagtt
    34621 taatatttta aatataaaat ttgtaaagct ttttgataaa tatgataatc aagataatat
    34681 aaataaagag attttatttg atataaaaga atcttcaaaa aatatataca atgccactga
    34741 aagccaattc aaaattagag attatataaa aaatataaat gcaggatttg ctctatatga
    34801 aagaagtgct caagatttat taactaaatt aatgacccat gaaaataaaa tatctcaaaa
    34861 tcaaaaaatc cttttagatg aaaagtttac cttagatgac tcaataaaaa atctctcaag
    34921 tattattgaa aacttttcta atgacctaca agttaaactg gatatgatgt ttgaaaattc
    34981 tttagatatt caagataagt tagatgttat gtttaataac tcttttatga atgatgaagt
    35041 tcctcttgat agtgaagaat tatttaagga tgatgttaat aatgtattta atccttttag
    35101 tgaagaaatt tatgagatag aggataaaga aataaaggtc ataggtgagg atgagttaaa
    35161 tgaataataa atatagaaga actgttaaca gagaatttga aaagagtagc ttttggccaa
    35221 catttacaga tttattatct actgtattga tggttgtgat tcttatctta tttagctcag
    35281 aaagtatttc aggttctgtt gaacaagatt tagctaagaa tgtcaatgct tctgttgaag
    35341 aaacttttaa aaaaagtgga atacctgtga aggtagataa atctaatggg caagtaactt
    35401 ttggtgaaaa aaccatgttt gatgtagata gtgatgtttt aaaaccagag gctaaagaaa
    35461 tgctaaaaat gtttgttcca aagtacatag agactattta taaagattat ggtgactata
    35521 tatccaaaat agttatagaa ggtcatacag atgatgtggg aagttatata tacaacttag
    35581 atttatcgca aagaagagca tatagcgttg ctaaatttat agtgggagat gaaataggtg
    35641 actataaata caaagataaa gtgactaagc atattattgc aataggaagg tcaaaagctg
    35701 aactcatcaa aaatggtgac aatagcgtga atagagatgc atctagaaga gtagaactaa
    35761 aatacgaaat aaatattaat caaaataaat aattaaattt ttataaaaaa aaagaaggca
    35821 gttggtgtga gctttaagcc ttctttaagg aaaaagttta tttatttttg ttgatactta
    35881 acatattata gtttttagaa gcagtttgca atatattaaa cgtaaatggt cgtttaaaat
    35941 gcataactgg atactactga tgtaaaatat ttcattttat ataatataaa aattatacag
    36001 tgtcaatttt ctatattatt gtactataat ctattattta aaatattatg taaaaaaata
    36061 tcataaaaac gcatatcatg ttataattac tagagtatta tgaatatgga ggcgtagttt
    36121 gtgatagaaa taagtataaa aaataaaaaa aattctaaaa ttaaaacttt gatactttta
    36181 ttgatagtat ctatatcgat ttatttaact ggttgtacta catcagataa tggaaataat
    36241 caatcaaata ataatgattc tttgtctagt agtatatcaa gtgataagaa tgtaaaaatt
    36301 cattttattg acactggaaa tagtgatgca atattgattc aagatggtaa aacttttaca
    36361 ttgatagatg ggggagataa tgatgatgag ggattaatgg tagattacct aaacaatcaa
    36421 ggtgtaaaag atattaaata tcttatagct acccattctc atgcagacca tttaggtgga
    36481 cttgattctg ttgtcaaaaa ctttaatata gaaaatgttt ttgtatcgaa tggttcagca
    36541 gaaacaaaga gttataggga ctttataaat gctttagcaa ataagggttt atccccaagt
    36601 gtaccgcttg aaaataataa gttctattta gaagattctt attttgaagt tctaaataca
    36661 aatgggggag atactactaa tgaacaatct ctagtccttg tatatactaa tgggaatgat
    36721 aaagttttat ttacaggtga tgctgaagaa ggtaccgaaa aagaaatact acctaagctt
    36781 gagaaagtag accttttaaa agtagctcat catggttctc gtagtagttc atctcaagag
    36841 tttttagata aagtaaatcc tgaatatgcg gttcttttag taggcaaggg taattcatat
    36901 ggtcatccac atcaggagac aatgaataaa ttaaaaaaaa tgggagtaaa agtgcataga
    36961 agtgatgagt gttcagatat aatatttgaa tcaacaggtg atggagtatt tacaagttgt
    37021 aaagatggaa gttataataa aggcgttaga gaagatggaa actctggaaa atcaaacagt
    37081 aatacaagta aaaatgattc ttttaaaaat aaacaaaata catccaattc agaagaaata
    37141 gtgtatttta ctccaaaagg taagagctat cactctacaa aaaattgtag tgggctttca
    37201 agaagtaaaa aaatattatc aggcacaatt gcagaaagta agaaaaatga cccatgtgat
    37261 atatgttatg gaaaataaca aaaaaacaac caatttatct ataaagcttc tgaactttaa
    37321 atcatttaaa aaataaaata aatgcataaa aaaataagct ataatcaata gataacacat
    37381 tttatctata cgaatagctt atttttttaa gtatttttta atagctattt aataactcta
    37441 aatacaccag ttacaatacc tacaatttca acttctgagt cattgagcat aattggttcc
    37501 ataaaatcat tttctggctg aagtcttatt aaatttcctt ctttaaaaaa cctcttaacc
    37561 gtagcagatt caccatttat aagtgcaact actatctgag aatttaaggc tgtatttttt
    37621 ttgtctacta caacgtaatc ttcatctaaa attcctgcat taatcatact ttcgcctttt
    37681 actcttaata caaaattgtt actgcccttt actaaactgg cagggaatgg aatgtattcc
    37741 tctatgtttt gttgagctaa aatgggttct ccagctgtta tttgacctac taaaggaagc
    37801 tctattattt cttgattagc tccagaaaca tcatttactt tactacgttc taaaacttca
    37861 atagctcttg gtttagtagg gtcctttctt atgtatccca gtttttcaag tttatttaga
    37921 tgagagtgca cagttgaagt agatcttaac cctacagcag tacatatttc tcttacagca
    37981 ggtggataac cttttaatat gatttgagac tttataaatt ccaatatcaa gacttgcttt
    38041 tcagttagat ctaaatacat aacatcactc atttccaaac atattttgtt tttatttcca
    38101 tacactttat atttttaatt ataacataat ccatttatat ctgcaaacat ttgttcctga
    38161 tttttaatcg tcctcaatcc attcaaaatt cttgactata tcacgtttta catttttctt
    38221 atgagctgca taaagctgag tagttgtgac attatcatgg tcaagtaagt tttgaacatc
    38281 atatatagaa aatcctgttt ggattagaga agttgcagcc gttgctctta atttatgggg
    38341 actatatcca ttgtctctag tagtatcaag tggaatagat gtatattttt ttaccagtgt
    38401 tcttatagcc tttgctgtaa ttctcttatt ttgaagagac aaaaataaag catctttttc
    38461 ttcatcattt aatagttcat ctcttgttct ttcgttttgc aaataatctt ttattacatg
    38521 ttcacaagta tgatttatag gcattaaaac ttctttccca cgttttctat atattttaaa
    38581 ttcacctctt gaaaaattaa aagaggagat attgagttct ctaagctcat ttaatctaag
    38641 cccgtatgta acaaataatg ctagtatagc tttgtcacgt aatttagttt ttctccaata
    38701 taccttttct ttctctgtaa gcccttcacc tgtttctact gattcaagca tcttagcaac
    38761 ttcatctatc tcaaggcgct taatagcatc tggctgaggt ttaggaagtt ttattggatt
    38821 gaatccatca gttatattat tatctatctg agagtttctg tataagaatt taaatagagt
    38881 agagatggat gatttttttc ttgctaaagc tctattgtta ttttcaaaaa tcaatgtgtt
    38941 tttttctgta tttttgtaat atctactgca ataatcacct aagaataaat ttatatctct
    39001 tgattttatt gtattaaaat catcttctgt aatgtctttt acacaatctg catttgttaa
    39061 ttctttggtt tcaatcaaat atgaacaaaa aaaattaata tcttctaaat aagcaagtcg
    39121 tgtagaaact gcaacagaac cttttaaata tataaaataa tccttcataa atacaggaag
    39181 tttattttcc aaaagtagac atttttctat gagttcattt tctttgataa caatattatc
    39241 aggtttatct gatttattat gtacttttat aattttctta tcattattca aaattaaacc
    39301 tcctaaaact aaaatataaa tcttttatat tattttttga tatttatact aagtgagtat
    39361 aaatatttaa tttaatcatt ttttacattt ttaagagatt agcagtgctt tagatgaaat
    39421 tatcactaac tattccctaa atccacattt aaagactagt tgaatttaag tactcttttt
    39481 tatttctcaa tatatttata taaatatatt gagaaatttt ttatgctcta ctagaatctt
    39541 ttttatataa tatttttata tgtttctaac gaaaccaaat attagtaaaa tatgtattta
    39601 tttaactaaa gtttttaaat gggctgacta agcttaaaat ataggatatt atgagagtta
    39661 ctattgaaaa aataaaccct attgccataa agaaacttat aaatatgtta tacttaacta
    39721 ttaaactgga tatattcaag ttatcaaatc caaataagta tgtaattgaa cttattacaa
    39781 aaataactat aactataaag ctcaggccat ttaagctatt ttttaaatca gcactactaa
    39841 gtgacatatg tgtagatata gaatacatta aaaacataaa tataaaatac ttcaatgaat
    39901 atacactagg tgttaacaac attattctta taaaattgga aatatcacct aaaataatgt
    39961 gtataaaacc atttatattt aaattattaa tcatgcttac atataacttt aaatctatat
    40021 tttgagtcac tttcatataa ctatctggca gtaatatctt aaaaattaaa ataatcatta
    40081 ttgttccacc tataataggt gcaattccta taaagaaatt tcctatactt tgataaagat
    40141 tatctttttt atagctatga cttacatatc ctagtatacc atcattttta ctttctattg
    40201 gtctgaaaaa cttaactgaa tttattttat gcatgaaaat taaacacatt atcaaatgac
    40261 tcaattcatg aacaaatgtt cctatagctc cagttacaat aattccagtt tttccaaaag
    40321 atgaaaatat aaatttatta tttagatttt ctgtaatgct aaaaatcaat ccaaatacaa
    40381 taaatattcc tatgaaacaa aaaatattta ttacacttat ttttaaaatt tcgattatat
    40441 aaatcataag ttaaatcctc atgtaaaagt atttaactac tctacttcat atccattaca
    40501 gcttaaaatt ttacaagcat tttctatatc cttttctttt actaagatat agtctgtatc
    40561 ataagtagaa attgcaaata tgcttatttt gttgtctgct aacaaactac ttaacttaga
    40621 taaaattcct acaagtgaaa agtctaaagg acctagtatc ttaagtattc tccactcctt
    40681 ttctgactta acatcagaag gaatattatt atttaaacat acaacactta attcatcatc
    40741 agttctagtt atagagtaaa acttctctgt atctatccat gttggtattt tactgtcatt
    40801 atttaatcta catactgcat actcttctac caataatttt aatttcataa tgtatatttc
    40861 ctccaatctt atttgtttac ttaagattat acattaaaag ttacataaaa taaaacatat
    40921 aaagtaaaaa aggttcacta tagtgtccta tttctatagc caacctttaa aacttaatta
    40981 aattctaata aagagatata ttatctaggt tcaattataa gtttaatggc tgttttctta
    41041 tcaccttcga tttctatatc agtaaatgcg ggaatgcaaa ctaaatccat tccactaggt
    41101 gcaacaaaac ctcttgctat tgcaattgat tttatcgctt gatttagagc tccagctcct
    41161 atagcttgta tttctgcaac gcctcgttct cttagtactc cagccaaggc tccagctaca
    41221 gaattaggat tagattttga tgaaactttt agtacctcca tttcaacatc tccttgttaa
    41281 tttgttaaag tatccattac ctaaagtact aaatcataat tgccatttac taattacaat
    41341 catcatttaa agtatacttt tataaaaata tacttctata atcgttttaa gaaaaccttt
    41401 atttttttta accattttat tatgaaaaaa ctacaaattt ctttatattc tataagcatt
    41461 ttccaatatt tctaaatttt ttatatcttt gagctataat ttcctcttta tccatatctt
    41521 tgtaatgatt taatctttct aaaatgtaag cttttatttc ttttgaaaca gcttctacat
    41581 ctttttgtgc tcctccaaga ggttctttta taatcttatc tattattttt aaatcatata
    41641 aatcattact tgtaagcttc ataacatcac aagcttcttt agctttagat gaatctttaa
    41701 atagaatact agaaagccct tctggagaaa tcacagaata aactgaatgt tctaacatac
    41761 atacatcatt tcctactccg atacctaaag ctcctccact accaccttca ccaattacaa
    41821 aagtgattac tggaacagaa agtttactca tttcaagtaa gtttcttgca atagcttctc
    41881 cttgtcctct ttcttctgct tctagaccac aaaaagctcc tgatgtatca ataaacgtta
    41941 ttataggtct attaaatttt tcagcttgtt tcataagtct taatgctttt ctgtatcctt
    42001 ctggatgagg cattccaaaa tttcttttta tattttcttt tgtatctctt cctttttggt
    42061 gtccaactat agtaacatta aactttccta tctgaccaat tcctccaacc atagaagggt
    42121 catctttaaa aagcctatct ccatgaagtt ctaaaaaatt agaacaaata tgttctatgt
    42181 attccaatgt cgtaggtctc tttatatctc tacttaatgt taccttttca tatgctgata
    42241 gatgtgaaaa agcatcttcc ttaagctttt ccaatttctc attaagtgaa tttattttat
    42301 cacttaaatc tatattattt gccttagaaa tagttattaa ttgtttaata tcattttcta
    42361 agacttttat tttttcacta ttattttcaa tcaaaacagt tcctccttta tgccctattt
    42421 cttgtgcata gcaagaattt gatataatac ttccttcatt tttcttctat ctactatcat
    42481 gtcaataaaa cctttttcaa gtaaaaactc agaagtttga aatccttcag gaagtttttg
    42541 atttattgtt tgctctatta ctcttggacc tgcaaaacct atcaacgtat ttggctcaga
    42601 aattataata tcaccaagca tagcaaaact agcagttact cctccagtag tagggtcagt
    42661 tagaactgat atatatggca atgatttttc ttcaagctta gaaagtgctt gagaagtctt
    42721 tgccatctgc ataagagata ccataccttc ttgcattcta gctcctcctg aagcagaaca
    42781 aataattata ggtaaattat tttcagcagc atactctatt gaataagtta ttttttcccc
    42841 aacaatagaa cccatacttc ccatcataaa atcaggattc attacacaaa taactgtttt
    42901 aattccattt attcttccat aacctgtgac aacagcttct gactcttttg ttttttcctt
    42961 ataagagtct actttttctt tgtatttagg aaaatttagt ggattttgaa attctacatc
    43021 agaattaaac tccataaaag ttcctttatc aatcaataaa tttattcttt ttcttgctct
    43081 taagccataa tgtcttgaac attttggaca tacaaatgaa ttttcttcta tgtcctttct
    43141 aaatacatga ctatcacaac ctttgcaata ggtccaaaat ttatcatcta cactattctt
    43201 tttaaagttg tcatctaaag aaatcgtaac atacttagat tcttttgatg ataaaaattt
    43261 ttttatcata atctatttac tccttataat gtagcaaatt ctttcttcat aaagacatct
    43321 tctataaatt tggtatgatg agtatcttct ctaaactcct cacttgttac aagtgccttt
    43381 tgaaattcta catttgtatt aataccttct acaataattt cgtctagagc tctatatatt
    43441 ctacttatac attcttctct agtttcagcc caacatatta acttacctat catagaatca
    43501 tataaaggtg gtatagtata tcctgcatat acaaaagtat caaatctaac accaaaacct
    43561 ccaggtaaat ttaatgattc tatcttacct ggtgatggag caaaattctt tgatgaatct
    43621 tctgcattta ttctacattc aatagcatga cctctaaaag taatatcttc ttgtttaaaa
    43681 ggaattttat ccccattagc tatagatatt tgaagtttta taaggtcaag atttgttacc
    43741 atctctgtaa ctggatgttc aacttgtatt cttgtattca tctctataaa ataaaagttt
    43801 ttatctttgt caactataaa ctcaatagta cctgcaccga tataacctac tccttttact
    43861 atatctactg caattttatg aagtttttgt ctttcttcat ctgaaaggta tggacttaaa
    43921 gattcttcta ttactttttg atttcgcctt tgcatagaac aatctctatc acctaaatgt
    43981 attgcatttg aatgtttatc tccaaatact tgtacttcta tatgtctagg attttctata
    44041 aacttttcca tatataaatc actattagaa aatgctgcta gagcttctga acttgccata
    44101 tcaaaatttg aaaaaagttc ttcttctttt ctaacgattc tcataccttt tccaccgcct
    44161 ccacttgagg cttttatcat aacaggatat ccaatttctc ttgcaacttc taaagcttct
    44221 tccttagttt tcaaaacaga ttctgaacca ggaacaacag ggatattcaa ttccatcata
    44281 gtttctcttg ctctagattt atctcccatc aaaatcattt gttctcttgt tggacctata
    44341 aaaataatat tattatcttc acattgcttt gcaaattcag gattctctga taaaaatcca
    44401 aagcctggat gaatagcatc acactttaat ttaagagcaa gatagattat attttctata
    44461 ttattataac tcttacttat attatttggt cctatacaaa tagattcatc agctatatat
    44521 ctatgaaaac aatctttatc tatttcagaa tagatagcaa cagtttttat acctagttct
    44581 ttacatgttc tgatgattct aactgctata tcgcctctat ttgcaactag tatttttttt
    44641 atcaacttaa atacctccta ctacaatggt tttatcttaa ataaaggttg attatattct
    44701 actagttctt cattactaac taatacttca attatttcac ctttaatttc acttgttatc
    44761 tcattcataa gcttcattgc ttctaatata cataaagtgt cgccttcttc aactacatcg
    44821 ccaactttaa caaagctatc tgcatctgga cttggagaat catagaatgt tcccatcaaa
    44881 ggagctacta ctactgatag attctcatta gatgtgacag gtgtatcgtt tacaactggc
    44941 ttttctaaag aaagatccac tactgattct tgttgtacac ttaaaacagg tgaacttgta
    45001 gattgagctt ttttagatac ttctaatctt aaatcgctac tttcaagttt tacatattct
    45061 aagttagttg agtctatggc ctttaataat tccttaattt cattgatgtt cattttgtta
    45121 cccccttgta ttattacctg gtgctaatat tatatcacaa aaaacaaatt tataaaagaa
    45181 aaagtgctga ctagagaatc aacacatcaa tatatctttt aattttaaat taacaaccag
    45241 taacttatat ttgttttaat tttccattat taatataaat tataagtata aaatgaataa
    45301 aattcaatat tttttgcaaa atacaagaga atacaaatta atacctcggg aatttttaag
    45361 acaaatacca atattatgca atttagactt cgctttcttt caaattagta tcattttctt
    45421 tatttttaca taggatgtac tttaatttag ctatcaaaac attgctatat aggttaaaag
    45481 ttattagaat tgcaggaatt ataaagtaaa ctctagcacc tataaaacca aaaactactg
    45541 taataagtat taatctttta tttaaagtaa aaaaaggtat attaaaaata cttttgtcgg
    45601 atgtttctgg agtataagaa tatataactc caaaaatcaa agtaagcata caaagtggaa
    45661 gtagtgtata acttgaaatt attcccaaaa atcctatact ttcaaaatat ttgctagcac
    45721 tatttgtata aacaaacatg tatccattta aatatgcgca tatacatgat ataatgccaa
    45781 aagttccccc taaggattga gtgtaccaat taaaaaattt agattccata tacctcacct
    45841 cctaaaactg tatatataat gatatgcatt taaatagtaa aatatatctt tatatgtttc
    45901 tgaataaaat tttgttaatt tcattaattt atgtttaaga aatttgaagt atagtgtagt
    45961 atatattaat gtagatgaag ttttatagta cttatttcat agtgcttaat caagttatct
    46021 tattatggat tcaaaagttg tttgtagggt tttatatttt gttgagctga aaaatttatt
    46081 ataaatgaag ggatgttttc gctttggtag atacattaga atttggtctt aaaattttat
    46141 tttttatatt atcaataatt tggatgggta aaataatgat tttaagaact gataagcaaa
    46201 tagtaatcaa tcctttgctt attggtatat ctgcaatcct tgtgatgttg catacctcac
    46261 agagtaacat tgaatttttt ggattagatg tccaatatat aagaatagtt ttgtatataa
    46321 tatattcact gataatttta ataggaatat gggctactaa cagaagaaat ggaatttttt
    46381 agataatcta tttctataaa atttaaaggt tgctagtaac aaatcactaa tattagcgtt
    46441 ctgttactaa caacctttat tttgattata cacttaaatt gaaaatagaa tgattgaata
    46501 agttgacaga ttattttaca ttgacagtaa ttagaacttc ttgagatgta tttaaatcat
    46561 ttttgtcgct tagtataact tttaccactg ctttacctgt tttattacct ttaattatca
    46621 tatcttcaca tgaaagtaca ctcttatcac ttacagatac aataaaattt aaatcttttg
    46681 gaaggttatc agtaacttcc cagtatttat aataactatc aattttcttc gtaattattt
    46741 ttctcaaatc aatactttca ccttttgcta tatcaacatt atgatattta gagtccagtt
    46801 tatactgatt atcttttgta tcaataaaat ttaaatcgca atttacatcc acaccattat
    46861 gagaaagaga atttactaca tcgtcatcaa tcaaataatt attggcaaga tttattgaat
    46921 ccatatcttt tagacttaaa gcttccttag gaacctcttt tatattatta ttccaaaaaa
    46981 taaaattgtc tacattttca agatatgata taccttttaa atttgaaata ctctcaccag
    47041 ttgcataaaa ttctccatct aaagccttta tattgcttat agtcatctca tctggattta
    47101 tatatctttt tacaactgct cttaaatttg catcaggaaa aatatcttta agttgatttt
    47161 cgctcaaaac cttatcattt gaatttattg gacttaaagc tgctgcagaa ataataaatg
    47221 gtattaaatt agctaaattc atagtaccct cccacataaa ttttttatta taataattta
    47281 atttctatga gagggttctg tttccttgtt atatatacct actttcgtac actttattaa
    47341 tataaattaa aataaatttc tactattaaa cttataaaca tattactagt tacgtttttt
    47401 agcttcacat ctaaatattc gcataccttg tgacataaat ttgtcttcat actctgttgt
    47461 aacattattt tcatactcac tatttcctaa atcaagagaa atattcttta atagccaatt
    47521 atttgcagca atttcattta aactaaactc gaataatttt tcattatctg ttttaaagtg
    47581 aatttcgcca tcatcttcca aaaccctatt gtacatttct aaaaatccag aatgagtgag
    47641 tcttctttta ctccatctat ttttaggcca tgggtcacag aaatttatat aaattctcga
    47701 taattcttta gcttcaaagt aatccaaaat attgcttaca tctccccata aaaatagtat
    47761 attattcaaa ttagaagcat ctgctttttc aacagctttt aaaagaactt cttccttaag
    47821 ttccatggca atataattta tgtcagggtt ctgcttagct aaagttgtta taaacttacc
    47881 ttttccagtc ccaaattcaa catgtattgg attatcattt ctaaacttta aattccactt
    47941 gccttttaat ttgtctatat cgtctcttaa aacatatttt gtataactta aaagcttttc
    48001 atctgcacct ttttttcgtc ttcttctcac aataattctc cttacatata aaaaattagt
    48061 aaaatacatt tttattatac attatctcac caaaaaataa aaagaactct cttaaaatag
    48121 aaatttattt ctataaagag agttctaaac ttactaaaaa cttaatctta gtggcaccct
    48181 gaacaaccag agcatcctcc tccaccttga tctttcatat tttcaggaat aactctaaat
    48241 ccaaatcctg tatcttctat tattatatct ccatactgac tatattcatc agagctcatt
    48301 acaaattgta attctccaac ttcataagtt aagtcatctt cttttttctc atctaaagct
    48361 aatccaaaag aaggacctcc acaaccaaca cctgcaaagt atactcttat attattaggt
    48421 ttatcttgat tgtcttttaa gatacttttt aaagtatcaa tagctgtttc tggtaaagta
    48481 attttcatca aatcattccc tttcaaatat tttattaaaa caatatctat tatataccca
    48541 tacaaggtac ataatcaatt agtttttgca tattttacta aaacttctac ctaatattac
    48601 ctaaggcttt aaaatatttt atataatatt ttattacctt aaataaatac cctatcataa
    48661 acttagtaaa caaataaaat tattattcta aaaaatataa taattttatt tgttgtttta
    48721 atattataac acatttgata atgtccaatt cata
//
LOCUS       DAYAOO010000025        48203 bp    DNA     linear   BCT 12-OCT-2024
DEFINITION  TPA_asm: Clostridioides difficile isolate ST8-SSI-h139-18
            SAMN40601845-rid21577343.denovo.025, whole genome shotgun sequence.
ACCESSION   DAYAOO010000025 DAYAOO010000000
VERSION     DAYAOO010000025.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN40601845
            Sequence Read Archive: SRR28438827
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 48203)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 48203)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-MAY-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-MAY-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002157583.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002157583.1
            Genome Coverage       :: 163x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/11/2024 16:19:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 4,038
            CDSs (total)                      :: 3,963
            Genes (coding)                    :: 3,930
            CDSs (with protein)               :: 3,930
            Genes (RNA)                       :: 75
            rRNAs                             :: 6, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 60
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 33
            CDSs (without protein)            :: 33
            Pseudo Genes (ambiguous residues) :: 0 of 33
            Pseudo Genes (frameshifted)       :: 7 of 33
            Pseudo Genes (incomplete)         :: 25 of 33
            Pseudo Genes (internal stop)      :: 11 of 33
            Pseudo Genes (multiple problems)  :: 8 of 33
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..48203
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN40601845-rid21577343.denovo.025"
                     /isolate="ST8-SSI-h139-18"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Denmark"
                     /collection_date="2018"
                     /collected_by="Statens Serum Institute"
     gene            complement(41..652)
                     /locus_tag="ACGI5H_001535"
     CDS             complement(41..652)
                     /locus_tag="ACGI5H_001535"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439113.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipoprotein"
                     /protein_id="HFG9697245.1"
                     /translation="MKMVKKLILSTIMALVLVLTIGCSNAEEKVKSNFEANLAALEMY
                     KYDEKGISDALTEAEYKQIQTYNSKDKVSMIAQLTPLYGKENAEKIYETIVKLIQGVE
                     KTVTVESSSKDKITLKVVSKALDTSKVMSEANTLVKSYVTDEKNYDKKEKEVQDDMTK
                     MIIDLYNKKPTKEVTTMITYTKKDGKWQPPSNIQKLCEGIYTI"
     gene            complement(744..1733)
                     /locus_tag="ACGI5H_001536"
     CDS             complement(744..1733)
                     /locus_tag="ACGI5H_001536"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439110.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ornithine cyclodeaminase family protein"
                     /protein_id="HFG9697246.1"
                     /translation="MLLLKKDDIKKVFTMRDAIEADKEAFRIYCEGKSVNPLRTNISV
                     PSQDASMLFMPGYVEELGCGGIKIVSVFPKNAQKGKPVIPATVLLLDGETGEVSAVLD
                     GTYVTQIRTGAASGAAIDVLAKKDSKIGALIGLGGQGEPQLEAMIEARNLDEVRVFSR
                     NKESREKFAEEMNLKLSKYNTKIVAVESSDEAIDNADVIVLATPSKQPVLNGNLVKKG
                     ALISAVGSYMPDMQELCPNCLTRASKIFFESTDAVLSESGDILIPLKEGKISKDDFSG
                     DLGNVINGTIPGREDDDEIIVFKTVGIGVQDVVTAKRIYDKAKENGIGIDWKW"
     gene            complement(1800..2663)
                     /locus_tag="ACGI5H_001537"
     CDS             complement(1800..2663)
                     /locus_tag="ACGI5H_001537"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728560.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3298 and DUF4163 domain-containing protein"
                     /protein_id="HFG9697247.1"
                     /translation="MKFFKVDTKAKVLRYVFVLTLTIMAVLAIKHDYKYNNLRKDASI
                     NLNSNKEAVTVMSNQSLPKGNTNSKQTLSVSTIGSKTIVKNDEYLESTINMPVITNSN
                     KIVERSTNDKIKNDIFEFYNKSYKEAKQYLKDNPDEKNKFVANVDFELKKNTDSALSI
                     KVRYYTYSGGAHGFYQDIAYNVDMRTGKFLELMDLFKDNTKYKEVIDEEIKRQIAELE
                     KKDEENIGIYNFKGIKENQNFYLQDENLVVYFDLYDITPYAAGIPEFSINKALISSML
                     KPEYVDLFDLK"
     gene            complement(2769..3365)
                     /locus_tag="ACGI5H_001538"
     CDS             complement(2769..3365)
                     /locus_tag="ACGI5H_001538"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895569.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CheB methylesterase domain-containing protein"
                     /protein_id="HFG9697248.1"
                     /translation="MERFNNMVIAIGASVGGTEAILEIIKDLPKSTPGIVVVQHMPAI
                     FTYMYAQRLDKQCIMNVREAKNNDRVEQGNVLIAPGGYQMKLCTDKQGYYVTCEKGER
                     ISGHCPSVDVLFDSVAEVAGKNSIGIILTGMGYDGASGLLKMKENGSFTIGQDENSCI
                     VYGMPMVAFDRGSVMLQLPLGEISNCLIRHINILKQKD"
     gene            complement(3405..4208)
                     /locus_tag="ACGI5H_001539"
     CDS             complement(3405..4208)
                     /locus_tag="ACGI5H_001539"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417907.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008168 - methyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:0008983 - protein-glutamate
                     O-methyltransferase activity [Evidence IEA];
                     GO_function: GO:0016740 - transferase activity [Evidence
                     IEA];
                     GO_process: GO:0032259 - methylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="protein-glutamate O-methyltransferase CheR"
                     /protein_id="HFG9697249.1"
                     /translation="MIKLTDEEFIVLVNHVKKEYGIDLSKKRALIEGRLYNTMIEKKL
                     SSFSQYMNLLFKDRTGNEAINLINRLSTNHTFFMREPQHFEFIQNSILPFWEENNKIR
                     NINIWSAGCSSGEEAYSIAMTLDDYFGYNKELWNIKIIATDISTNSLEKAKRGIYIES
                     NVNNVPELWKKKYFIDNKDGTFKICDKIRKSVIFKPFNLMNDFSYQHFDLIFCRNVMI
                     YFDLKTREELINKFYNATKKDSFLFVGHAEVINRSSTKYKYVKPAIYKR"
     gene            complement(4244..4684)
                     /locus_tag="ACGI5H_001540"
     CDS             complement(4244..4684)
                     /locus_tag="ACGI5H_001540"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439104.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0006935 - chemotaxis [Evidence IEA];
                     GO_process: GO:0007165 - signal transduction [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="chemotaxis protein CheW"
                     /protein_id="HFG9697250.1"
                     /translation="MAKDEIIKQVLTFYVNDVIYGIELENVIETIRFQSITYVPCLPT
                     YISGVINLRGRIIPVINMHIKYNLPKADYNERTCIIITKVDEYQVGIIVDKVVDVIHI
                     ENLNLLETTNSNNTNINKDIKEIAKVEDNSILILDIRKFLINSI"
     gene            complement(4697..6799)
                     /locus_tag="ACGI5H_001541"
     CDS             complement(4697..6799)
                     /locus_tag="ACGI5H_001541"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860851.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0006935 - chemotaxis [Evidence IEA];
                     GO_process: GO:0007165 - signal transduction [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="chemotaxis protein CheW"
                     /protein_id="HFG9697251.1"
                     /translation="MRQMLDMFIFETSLLLEQLDEIMIQIEKEKVFTHNNINETFRIM
                     HTIKGSASMMGLDNISALAHSVEDLFYAIREGKIEVLDNDLLFDLVFQSLDFIRRDID
                     ELQSRGCISSDYSNFIEGIEEYVSTLELSSSMKSKDNANLESKDEKEVIDSNFEYKED
                     SDVVKIIFEQGCMMENVRAFMLVFELRDYCEFIDFYPKDVETNAESTEYIKSYGFYIQ
                     FVAKEDKAIVYKTIEDNLYVKEYINISKKEIEMKSTSNNDAVENKLKDNNKVSKSYQN
                     NYTEDEIQEDVLNEKTDMEKDSLSEENEHLPISKQSIMSVNLEKLDLLQNIVGEIVIM
                     ESMVVNSVNSTGVDIDNFNKATRQLHKLTDELQDIVMSMRMIQIAGVFQKMHRIVRDM
                     NKKLDKNVELITIGAETEVDKSVIDNLAEPFMHLIRNAMDHAIEPIEERIAKGKEEVG
                     KIVLSAENLGGEAVISISDDGRGIMRDKILAKAKEQGLLKHQSNEYTDDEVNSLIMTP
                     GFSTKESITEFSGRGVGMDIVRKSIEKVGGSIEVKSKQDEGTTFTIKIPLTLSIVEGM
                     KFKVGDSLFTLPISSIRRTFKLTDLNQIITEGNKTELITIYGACIPIIRLHKIYNIQT
                     KVTNLMNGNMIIIENEHKAVCIFVDEIIGNQQVVVKPFPVYFNRFNIKNKGLSGCTIL
                     GDGSISLIIDADSIIEIY"
     gene            complement(7060..8763)
                     /locus_tag="ACGI5H_001542"
     CDS             complement(7060..8763)
                     /locus_tag="ACGI5H_001542"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888334.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0006935 - chemotaxis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="methyl-accepting chemotaxis protein"
                     /protein_id="HFG9697252.1"
                     /translation="MKREVKLSKLAIVLLIIIVLAVLAGIFSSISSYKAFEKVEKSIN
                     DMNNLRTQSQYIKDTTREISDVLRRYVFTGEKKNKDIYEKELYGKTRESALNKLEKIG
                     LTKSESNKILEAKEISDSLVPTEQSAIKAVESNDKSKAQSIIFGSDYINSQEKMDSLI
                     NEFQEDIVTRSNSKIVEVKKELQSLILRTIFILSLLIILTIIEYTVIKLKIVIPINKV
                     EKHFSRIASGDLRTSIDVEESKSEIGLLVSSVKKMQSMLLNYIDLIDSTLTSIAKGDL
                     RVEIDQEFIGDFKSIKISLESIINSFNGDFSEINLSAEQVASASEQVAAGAQALSQGA
                     TEQASSVEELASTINEISDGIKKCADSASLACEVSDQSASQVGFGSRCMDDMMTSMGE
                     ISEKSSEISKIIKTIDEIAFQTNILALNAAVEAARAGQYGRGFAVVADEVRSLAGKSA
                     KAAQNTAILIEEAIKTVENGVRIAKETANALDLVVNGVEKTTNYINGISSAVHSQEVA
                     ITQILSGIEQISIVVQMNSATAEESAAASEEMSAQAQILKELVEKFHLKESEVRESSW
                     V"
     gene            complement(8789..9748)
                     /locus_tag="ACGI5H_001543"
     CDS             complement(8789..9748)
                     /locus_tag="ACGI5H_001543"
                     /EC_number="2.7.7.65"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895564.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0009975 - cyclase activity [Evidence IEA];
                     GO_process: GO:0009966 - regulation of signal transduction
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="diguanylate cyclase"
                     /protein_id="HFG9697253.1"
                     /translation="MKNKQQGTILVVDDSVLMCDLIDKTLTKDNFKVKKAFNAIEAKE
                     FIEEFIPDIILLDIILPDNSGFEFCKEVKSNARTADIPIIFITSKNTDTDIVKGFGVG
                     AIDYMVKPFSMTELKARVIAHLEVKKSQDKLKKINNELESSLEKLNRLVVRDYLTGLY
                     NRRHIINQLMEQRRINKYSETSISLILGDIDDFKVINDTYGHEAGDFVLTVISSIIKK
                     NCRQIDTVSRWGGEEFLIMLTNTPIEGAKILSERIRKEIKEFDFNYKEHKIKCTITLG
                     VVEVNSNISLEENISLADKAMYEGKNLGKDCSVVSTMKGLKKI"
     gene            complement(9884..10402)
                     /locus_tag="ACGI5H_001544"
     CDS             complement(9884..10402)
                     /locus_tag="ACGI5H_001544"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439100.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0006935 - chemotaxis [Evidence IEA];
                     GO_process: GO:0007165 - signal transduction [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="chemotaxis protein CheW"
                     /protein_id="HFG9697254.1"
                     /translation="MRFPDDPYLDYGLIDEGIKYLKFKVDEQDFGVELEKVIEITGNQ
                     EIIFIPELPTYSKGIINLRGKIIPIIDMRLRLKKDELMTTNCMYIVVTEIKDLVVGFV
                     VDRVDDIVSLEKSKISPPPRVTIEYSDYFVSGVGELEGKIITLLDLEKLLTDKDEVLI
                     DELINGFDCTIM"
     gene            complement(10445..10930)
                     /locus_tag="ACGI5H_001545"
     CDS             complement(10445..10930)
                     /locus_tag="ACGI5H_001545"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425085.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chemotaxis protein CheD"
                     /protein_id="HFG9697255.1"
                     /translation="MNREIVVNIADMKIAYRPNVLVTYALGSCVGVCLIDKVAGIGGM
                     LHVMLPYSKDAINIENKCKFADTGINELIKSMENIGANRIYIKAKIAGGAQMFLGSSN
                     SVIASIGHRNVEAVKKTLLGLNIPILAEDTGMNYGRTIRFYTETGELLVDSINKGKKK
                     L"
     gene            complement(10927..11574)
                     /locus_tag="ACGI5H_001546"
     CDS             complement(10927..11574)
                     /locus_tag="ACGI5H_001546"
                     /inference="COORDINATES: protein motif:HMM:NF016398.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chemotaxis protein CheC"
                     /protein_id="HFG9697256.1"
                     /translation="MNAIIKGGVYIINYLELDDVHIDALREIGNIGSGNAITALASMI
                     NSNVEVLIPMVKILEYNEATNLLGGPENKVVCILLDMKGDINGMFMFLLDESITQLML
                     SSLFNKEEAFLDEIEAIEISAIKEIGNIMASSYVNAIASMLNMTISVSIPDICIDMVG
                     AVLNVPMIRFSDVGDKVLFIENKFKMSDNYFTSHILMIPEMSSLREILVRLGLEV"
     gene            complement(11609..11971)
                     /locus_tag="ACGI5H_001547"
     CDS             complement(11609..11971)
                     /locus_tag="ACGI5H_001547"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator"
                     /protein_id="HFG9697257.1"
                     /translation="MENKILIVDDAIFMRMIIKEALSKSGYNNLIEANDGEEACNIFK
                     YEKPDLMLLDITMPKKDGLEVLREIKKLDSSAKVVMCSAIGQENMIVEAIKLGALDFI
                     VKPFKTETLVKVVDNALK"
     gene            complement(12715..13212)
                     /locus_tag="ACGI5H_001548"
     CDS             complement(12715..13212)
                     /locus_tag="ACGI5H_001548"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728567.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GyrI-like domain-containing protein"
                     /protein_id="HFG9697258.1"
                     /translation="MNYEIVEINEKIVIGISKETTNKDGQAVNDIGELWKKFMGKGIY
                     NAIKGKKNDKTIGLYTDYQGDFTSPYSFVACCEVNSNSDKEKNLEELNTNNTVGESII
                     SKVIPAGKYAKFVIVGGQKEVGDFWFEFWQMDFDRTYISDFEEYQCNTFDTKKQEIHI
                     YIGIK"
     gene            complement(13387..14298)
                     /locus_tag="ACGI5H_001549"
     CDS             complement(13387..14298)
                     /locus_tag="ACGI5H_001549"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439096.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HFG9697259.1"
                     /translation="MKINRLTEIIVILLNKKLVTAKELADRFEVSTRTIYRDIETLSM
                     SGVPVYMTKGKGGGISLIEEYSIDKAILSKKDKESLIVALKTLQATKYPEINSVVNKI
                     GSIFGEQNFSNWIEIDFTEWGSNFNEDDKFTKIKEAILRRNTINFNYVNSLSSQTNRT
                     VEPLKLMYKSKTWYLYGFCKLKDDFRIFRISRIRNLSIKDEVFSRKIIEEVCLNDSKV
                     IKENTITLKLRFKEKMLFRVFDDFNKDLITKNEDDTYDVITEFPIGEWIYGYILSFGD
                     NVEVLEPKDVRDNVITRLRELSKIYSL"
     gene            15222..16073
                     /locus_tag="ACGI5H_001550"
     CDS             15222..16073
                     /locus_tag="ACGI5H_001550"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425075.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3100 domain-containing protein"
                     /protein_id="HFG9697260.1"
                     /translation="MEINKKHFIQVFLTCLILVVICEFIGQRTIAIGKASIVLFPMLY
                     AVIIGLIITPDLLGKKIKALKKVVGEKEINIAGEVVGIALVMLGIKYGTTVGPNIDKI
                     IQAGPAFIAQEFGHILAPIVALPLALMFGMKREAVGATASISREPSLGVISEKYGINS
                     PEGSGVLGTYLMGTVLGTIYFSVLGSISIYSGLHPYALGMACGVGSGSMMTAAAGSLS
                     TMVPPEMADTILAYAATSNMMSSITGIIFLVFVSLPFTNFMYKILEPKFSRNKKTKEI
                     KSTEGEC"
     gene            16077..16547
                     /locus_tag="ACGI5H_001551"
     CDS             16077..16547
                     /locus_tag="ACGI5H_001551"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417884.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9697261.1"
                     /translation="MFANLNLKKSSYQLLVMSVIGVIILIGQRISVGTSIVTALPGMV
                     MLILAAMAAMIIKDLFPKSIFPAFGFATIIGLLLSMPYSPTSEVFLTNTNNINFMAIT
                     TPLLAFAGISVGNKIEALKEMSWKIVIISLIVFTTIFFACASIAHIVLSIQGKI"
     gene            16560..17870
                     /locus_tag="ACGI5H_001552"
     CDS             16560..17870
                     /locus_tag="ACGI5H_001552"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888329.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004180 - carboxypeptidase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="amidohydrolase"
                     /protein_id="HFG9697262.1"
                     /translation="MNKEQLKSLVIKTIDENREKILKIGQGIYKNPEYGYKEFKTTEA
                     VSNFFEQELNLSVEKNIAVTGCKADANSSKKGPHISILGELDGISCKEHKDANEIGAS
                     HTCGHNIQIAGMLGAAVGLVKSGVLEHLDGKVSFMATPAEEFIELEYREQLKKEGKIT
                     YFGGKQELIKRGYFDDIDISMMFHASDLGEDKALVGPESNGFVGKKVKFIGKESHAGS
                     APHDGINALNAAMLAINNVNALRETFKESERVRFHPIITKGGDIVNVVPADVHMESYV
                     RARTINGMIDANERINKALMAGGMAVGADVEITEIPGYLPILRYKSLDNLFKNNLEDL
                     GLKGKVIDGGDFTGSFDFGDVSHIMPTLHPMIGGVKGALHTRDFEIVDEDLAYIIPAK
                     AMALTVVDLLFDNAKDAKDILDTFTPVMTKEEYLTFLEKHDKTL"
     gene            18082..18828
                     /locus_tag="ACGI5H_001553"
     CDS             18082..18828
                     /locus_tag="ACGI5H_001553"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009901983.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HFG9697263.1"
                     /translation="MFNAGNRIINTWLYPIQDGFVLIDTGYENGFKHFKKRISKFNIK
                     IKDIRYIFLTHAHDDHVGFLNQILDESPNTKIVMHDKALEILYKGQNSFIGGCTSRTA
                     FLFCQIMKLFGKGEHSFSPLKQEFEKRCILVSDKNRKEIEKELNGKIIDTPGHTDDSI
                     SLLIDEGVLFCGDSAMNGFPSTHKITIFAESKLEFIQSWKTIINTKPKMIYPGHGKPF
                     EYSKLEQNLIYVNKINLYPLHNSKDIHRFL"
     gene            19190..20731
                     /locus_tag="ACGI5H_001554"
     CDS             19190..20731
                     /locus_tag="ACGI5H_001554"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417871.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AbgT family transporter"
                     /protein_id="HFG9697264.1"
                     /translation="MNDNVVKKKNFFDRTLNRIETVGNKLPDPVTIFLGLCVLLLILS
                     SLVGSMGISVVHPGTGETITAVNLLTVEQLQILLGNIVSNFQGFAPLGLVLVTMIGAG
                     VCDKTGLMTATIKASVSKIPETRVTLVVMTIGMLANIASDAGTILFPPLAALVYLGVG
                     RHPLIGLFSGYAAVCLGFAANIMISVNDILAASFTVPAAQMIDSGFQANATMNLFFMI
                     ASTFVLILLATWVTEKIVAPRFGKYEGNAELDVDGSLSDVEKKGLKKASISILIYVAI
                     IVALSVIGKKPFLADPETGDLLSNNAPLMKGMVPIIALAFFIPGVVYGKTIGKIKKDK
                     DVVSIMASAMSDMGGYIILAFAASQFLQLFTNSNLGLILAVKGGEFLKSAGINGPLLL
                     IGFIILSCFINLFIGSASAKWAILAPIFVPMFMMVGYNPALTQMAYRIGDCITNPLSP
                     LFPYFPIILAFTRKYDKDAGMGTVIANMIPYSISFLIVWTILLILFMVFNIPLGPGIL
                     PSYSM"
     gene            20766..21872
                     /locus_tag="ACGI5H_001555"
     CDS             20766..21872
                     /locus_tag="ACGI5H_001555"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417868.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="M20/M25/M40 family metallo-hydrolase"
                     /protein_id="HFG9697265.1"
                     /translation="MLDKNRLINNFMDMVRIDSPSNQELEMSKWLVNYLKERNIDAII
                     DDAGEKYGGNTGNVIAYIKGEEGSRPLCLCAHMDQVQPCLGVKPILDGNVVRSDGTTT
                     LGADDKAGIAAILEALEHVITEKIPHRDIYLCFTICEEAGMHGVKNFNPDNLPCKDMV
                     ILDSGGAIGSIAYKAPAQQSIKISFQGKKAHAGIEPEKGLNAILVASHAISNMHIGRI
                     DSLTTSNIGEIEGGGATNIVTDKVTLTAEIRSHIPETLEYELNHMEKCCKDAASKFNT
                     TYTFEHNMSYPSFELSRDSHVFKLSEEAIRQVGVVPNPMVIGGGSDANILANLGYNCA
                     ILSLGMYDVHTVNEYVNIDELYDTAKIVYHMIKL"
     gene            complement(22251..23537)
                     /locus_tag="ACGI5H_001556"
     CDS             complement(22251..23537)
                     /locus_tag="ACGI5H_001556"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417866.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="HFG9697266.1"
                     /translation="MIVGIIGPSDSGFKIKDDLKQIDSDLKTKIYVREKVVDTIEVIS
                     KCEDECDAIIFTGCAVYEFIKSKYEISKPHSFVPRSGTSIMKAFWAIKSANIKLDKFS
                     IDVVDRYVVEDALKEFDIKATSVFCNPFSLEVGESELVEWHIKLFEENKTDIMLTGFG
                     AVYNELKERGYPVFRLQATIQLIKESYDKVKSEYALSKARFSQIAVEILSLIDYKEKI
                     DNYYSDMIKKSDMDKLVVNYVRSIQGSLFLLGRNDYVVFVHKGVADNEYNYDKLFNLK
                     REIKDMGFSLSIGIGTGVTAYQAENNAHKALRHSIDSKEIGIYLVDEDENIRGPLASE
                     NELNYSLMLSDEKVIEISKKTGMSCESVAKIIAINENRKSKIYDSKELAEYLNVSERS
                     ARRILNKIVNAGLGRICAKETSIGGGRPKNITEILF"
     gene            complement(23660..26758)
                     /locus_tag="ACGI5H_001557"
     CDS             complement(23660..26758)
                     /locus_tag="ACGI5H_001557"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009904951.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EAL domain-containing protein"
                     /protein_id="HFG9697267.1"
                     /translation="MDVINLIDELDEIVYVSSLDTYELLYINEIGKKAMGLNDISHLK
                     CYKALQGKDSPCEFCTNSILKEDEYYIWENTNTRTNRHFILKDKLIKWEGKHARLEIA
                     LDITEKEDISKSIAEKLEIKELLVGCIKHLITESNFSDAVNLVLTNIGKFHKADRAYV
                     FEVSEDRKKVTNTYEWCNEGVDEQKQALTNLDINELKNWFLLFEQKGFVIIDDIENIK
                     EEQPIEYEILKPQKIESLMTSSLKQDDKVVGFIGVDNPHKAVGDTSLLTSLSYFLLTE
                     MKKRKVENKLNYMSYYDFLTGAYNRNKYIKYIDNFQKGKVKSIGVVFVDINGLKDIND
                     NFGHANGDSAIVSACVIIKKYFHSYNVYRIGGDEFVVLCEDISKQLFEELVSWLSEEF
                     KDEMIYSVAVGSIWSDDNIDIHKLIKVADERMYQDKKRYYNKNKLRNNEMKVISDLAD
                     STNNILFKHKELVDKVYFDDLMIKGYSKAYEKLAYNTYDIILSICIDTNLITPIYQSE
                     SNIFSFPIKENLEKTFSYIKKHLIHPDDIILFNDNHLLKSLDSLNNSKQDDLELNFEY
                     RRLGIDKKYYWALIYMLKISSKNKLGEKQTHILVAIKNIDYLMQLHKNQKDTLTGLYN
                     YESFCEQISLMLKRYPDKRYAIIMMDIDKFKVINDIYGVRGGDKALIYVAELIQKNIG
                     SNGICCRMYADVFCIFYESYSDRDIHKVIYKIKNSLNRKKFEYMLVPCFGVYRILDNH
                     IPITNACEMAGYAHKKVKKQSINNYIFYDDTIRNDALEEKQMEREMEYALENGQFHVY
                     LQPKYNLNANKIVGAEALVRWVHPEKGIIPPIKFISLFEKNGFIIRLDMYVWEQVCSL
                     IRKWIDLGEEPVPISVNVSRLHLHNPHFKEIVLSLINKYSIPKSFLELELTESLFIKN
                     IKLFTKIIADLRMDGIVLNMDDFGSAYSSLNMLKNINIDTLKIDCGFFNEEGITDREK
                     IVLKHTIAMAKDLDMDVVAEGVETKEQAEFLVTLDCVVIQGYYYCKPIPSADFEKLLY
                     QK"
     gene            27484..27642
                     /locus_tag="ACGI5H_001558"
     CDS             27484..27642
                     /locus_tag="ACGI5H_001558"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425061.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9697268.1"
                     /translation="MKIFSFLLFVIGICLCIAGFIGHYPVFVGTTLSFLAIAMIAVRQ
                     VKTKKKMK"
     gene            complement(27929..28633)
                     /locus_tag="ACGI5H_001559"
     CDS             complement(27929..28633)
                     /locus_tag="ACGI5H_001559"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439080.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HFG9697269.1"
                     /translation="MEIKPLVLIVEDDKPICKFIKVSLETQNYRCVETDNGGTAISLI
                     HSLDPDLIILDLGLPDIDGIEVIGRVRACAKTNKIIVVSAREHERDKVEALDGGADDY
                     LTKPFSVTELLARVRVALRNKAQQDNINNDAPKSFEVKNLKIDYENHIVSINGEEIHL
                     TPIEYKIIELMSKYSGRVLTHKFIIDKVWGNYYESENQSLRVFMASIRRKIEKNPAQP
                     EYILTEVGVGYRMADE"
     gene            complement(28624..30231)
                     /locus_tag="ACGI5H_001560"
     CDS             complement(28624..30231)
                     /locus_tag="ACGI5H_001560"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417858.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4118 domain-containing protein"
                     /protein_id="HFG9697270.1"
                     /translation="MKKERLQHEDLKEYDYDEDGYLSKKIIIKDFIKTILVMTIATGI
                     SVVFEKVGFNESNIILVYILGVLFATSITYGYFFGILSSVIGVLSFNFFFTHPLYTFL
                     AYRKDYPMTFCIMLMAAIITSTLTSRIKREVRLSHKREKMIRLLYENNKTLLKAKNKN
                     QIIEFCGSNLVNILNRTVIVTIADENNNLGKPSIYICNNDGSENIFHSVLEKEAIKEA
                     FRTGNPVGIGTKYCKNSSAYYFPIKGQESNVLGVIGVACFKIDIITENEKILLEAVST
                     QVALAIDRENLFEKNKKANLEAERERLRGNLLRSISHDLRTPLTSILGSSSTILENDD
                     VIDKETRVELLKNIYEDTSWLTHSVENILSMTRIDEGKLDIEKRPEVVDEIIAESILR
                     VKKFANSRDIKTNIPDEIIIVHVDVLLIEQVLVNLIDNAIRHTPKNSKIELTVKKESN
                     QVLFEVADNGKGIPNEDIGNIFNRFYTKNKSRNLERRGIGLGLEICKSIVEAHGGEIV
                     AFNNPSGGATFRFSIPMYDEEGKDKWK"
     gene            complement(30485..31663)
                     /locus_tag="ACGI5H_001561"
     CDS             complement(30485..31663)
                     /locus_tag="ACGI5H_001561"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439078.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9697271.1"
                     /translation="MEKLSDKRRVKAVSMETFVFIVLLAVGFGYVGSIMGAGMMFKVI
                     MSTAHALLLDTVFLIMAMAVLAGALSALLSEFGVISLVNKIFKGLMRPIWGLPGASIA
                     GVVATYLSDNPAIIPFAKDKTFTQYFKKYQVPALCNLGTAFGMGLIVTTFMIAQGKEY
                     VLPAIIGNVAAIIGSIISVRIMLTFTKKYYNYDPKNDTEKQINDKGAKLEEFREIRDG
                     NVFQRTLDAILEGGKLGVEMGMAIIPGVLVVCTLVMLLTFGPSTDPATGQAVYTGAAY
                     EGIKLLPAIGDKISFIIEPLFGFTSPEAIAFPVTALGAVGAAISLVPEFIKSGAITPN
                     DIAVFTAMGMCWSGYLSTHIGMMDALDARPLAGKAILSHTIGGLCAGICAHFIFMLVG
                     "
     gene            complement(31889..32383)
                     /locus_tag="ACGI5H_001562"
     CDS             complement(31889..32383)
                     /locus_tag="ACGI5H_001562"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417852.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonine/serine exporter family protein"
                     /protein_id="HFG9697272.1"
                     /translation="MHLFIEVIAAFFTALSFGVLFNMKGKNLILAGIGGSIAWFSYKF
                     LLNIGVTENLCFFIATVCFAIYCELCARIYMTPATTLSVCCLIILVPGYGIYNTMYSV
                     LTNNYIKAVEYGVSTLSCASSIALGLVFITTVFRKVNLYGVLTKIKENEKYKKSINKI
                     KQQK"
     gene            complement(32384..33145)
                     /locus_tag="ACGI5H_001563"
     CDS             complement(32384..33145)
                     /locus_tag="ACGI5H_001563"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888325.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonine/serine exporter family protein"
                     /protein_id="HFG9697273.1"
                     /translation="MDIDRILNFSSNAGKAMLQSGGETYRVEETIARICQSFGIDHVD
                     VFATPTAVMASVFVDGKLHSAIKRISSRRVDLNLVHEVNSLSRAISINNLDIELCEKI
                     LDEISEDNYYSDLITIFFAGIAAATFSILFGGNVEEFIAAFTVGILTKFVIMYLSKSS
                     LNDFFVNAIGAVIIASCSILILKLGFIKTLDHLIAGAIMLLVPGLALTNALRDLLDGQ
                     LISGLAKLAEVFFVGVSIAVGMFLVLGLYFKLGGI"
     gene            33847..36681
                     /locus_tag="ACGI5H_001564"
     CDS             33847..36681
                     /locus_tag="ACGI5H_001564"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417846.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0008134 - transcription factor binding
                     [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sigma 54-interacting transcriptional regulator"
                     /protein_id="HFG9697274.1"
                     /translation="MLRKDKVLLSLHKLCENMTLKDLQSDKTGFTTIEIANHSSLDRS
                     NTSKELNNLYNEKKVLKISGKPILFLHASIIENLIGRTLNSDEFSINNCNELLKSSKN
                     DSEDIFSTLLGHDSSLKLPIEKAKSAILYPPKGLNTLLIGPTGVGKSTFAETMYKYAV
                     ESKIFSSESKFVVFNCAEYAENANLLLSNLFGYVKGSFTGANKDKFGIVAQADGGILF
                     LDEIHRLPPEGQEMLFLLMDKGIYRRLGESDIMHKANVFIVCATTEDIHSSLLGTFLR
                     RIPVTINLPALQDRSLKERLSLIKYFFIIESKYTNATIKVHKDVIKSLLLYDCFGNIG
                     QLKSDIQLMSARAFLNYKTGLKDNIEIDLSLVPDYIYIGLLKLNENRSNLNKLSELDY
                     MLFYEFNGNNLEVEYTKELSKYNIDTSNNGFKYSTEIPYLENDIRSMFINYMEKYSTK
                     LLSISSVTHSDYTSNEIFKVINPKIYYAVEHSLKEAEKISRNKYTKQTYIALSMHISA
                     LIENINQDTYNPKYNLYNDKIFLDKDLNIAKIVLSIIENDLQTSLPKDEVKFISMFLN
                     SMYLEPNNQSESIGVIILAHGNSTASSMCDVANSLLGTNHCNAIDMPLDVKVSTILDK
                     TIELVKECDEGKGVLLLTDMGSLIAFGELISEKTKIKTRSIEMVSTPIVLEAVRKSTL
                     PEMTLDELANSLSSLNPYIGRAAIDSTEINYPEKSREYVIITTCITGYGSAMKVADFI
                     NSSLKNISKYNINLVPHNIESFKMYKNKFSNTKILAVVGSVDFNVANTPFIHIEELLN
                     GYGLDMLNKIIEGTFNANSITNIKETNLSYNSLIINFMTQNLELLDSVKLFNYVNSSL
                     FTIIELIDENLKSKFKLGYILHCSFMIERCFKNTTFPYNNITELISKNHELYSLIREA
                     FKPTEAYFNILIPDEEIAYIIDMINEYLNK"
     gene            36724..37968
                     /locus_tag="ACGI5H_001565"
     CDS             36724..37968
                     /locus_tag="ACGI5H_001565"
                     /EC_number="3.4.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439074.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008236 - serine-type peptidase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanyl-D-alanine carboxypeptidase family
                     protein"
                     /protein_id="HFG9697275.1"
                     /translation="MEDEILKGKIKQLTILALIFIFITPVFAFADTPPVPNSSRAALL
                     IDQETKRILFEKNIDEKMPLASLSKMMTFLLAIEAVDKNQVKETDMVKIDKSTASVGG
                     STCKLKDGDEISLGELMQGLMLVSGNDAAIAIAKHIGKTEKNFVNMMNKKAEEIGMID
                     TYYFNPNGLPIYTDPEHKEPPIENMSTAHDIVTLGKYMYDHYENQVTRITTMQVYNDT
                     KKDFTHYNTNPLLVSVPGVDGIKTGYTDNAGYCLAFSMMVPKDAKNERNHRLIGVVLG
                     DGNKKNRISSSATLLKYGKDNFHSKKIAHKGDIIETPCVDGIDDFKITVKVDKDLYGV
                     VSDNENINPKVVFKNMNYPIHKGDIVGVAKYYNDSGKFVGSVDVKSESNIGCIPLKDK
                     IKIKVAKINKKLEIKNSVCFKA"
     gene            complement(38383..40125)
                     /locus_tag="ACGI5H_001566"
     CDS             complement(38383..40125)
                     /locus_tag="ACGI5H_001566"
                     /EC_number="7.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009906256.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HFG9697276.1"
                     /translation="MKKTINNNLFRILNIIVYKNKTKLIVSFIMVFIIAGVNIVIPQL
                     IRCIIDDGIGNKNIFLLINLILIYIFIRILSATFDVILSYLYTSIKNKVTINLKVKLL
                     NHISKLSGRYYSSKKTGNILSIMESDIFMIENFGAEIIFDIIVNVFTAIISLIFLINL
                     QFDLFLVVLFLQLILTFSQNKMTKLISKKISEIRSDSGSLSNLIQEYVSNIMDIVILN
                     SKKNFFNKYLKRERDLIKKDLNLNIIMSSNIAISQILTGLITILIYGIGGYKIINNKM
                     TMGELIAFQQYTGMLIGPCIAIVRANTRIAQSKVSINRVFSVIDEKIDIKVDNNGYRI
                     DNSEIKKIDFKNVSFRYGEDLNLVLNDINLQFEKGEVTGIVGGSGCGKSTITNLIYRL
                     WDINEGDILIDGVNIKDINLKSLRNNIDIVTQDQFVFDDTIKNNIVLNNKISDKELDE
                     ILEVTCLDDFIKNLDKGLDEVVGEKGVKISGGQKQRISIARALVSNKKVLILDEATSA
                     LDNISQKEILNNLKEYIQDKIVIIIAHRLSTIKSADNIYVLDKGRVIESGNDAELLHK
                     DGLYNKLVETADFA"
     gene            complement(40109..40783)
                     /locus_tag="ACGI5H_001567"
     CDS             complement(40109..40783)
                     /locus_tag="ACGI5H_001567"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018590550.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HFG9697277.1"
                     /translation="MKILKVKDLKKIYGKYENEVRALDGIDLDIEPHKFTAIVGASGS
                     GKSTLLHCVAGLDKPTLGNVYLDDVDLYTLNDDKLSEIRRQEFGFIFQSYNLIPVINV
                     YDNIVLPVLLDGKKEDKEYVMRLINKLGIEKQIKKYPNELSGGQQQRVAIARALANRP
                     SVIFADEPTGNLDSKTTNEVMNMLEWCVKEYKQTLVMITHNDNIAKTADRIITIKDGK
                     IDEKNY"
     gene            complement(40820..41809)
                     /locus_tag="ACGI5H_001568"
     CDS             complement(40820..41809)
                     /locus_tag="ACGI5H_001568"
                     /inference="COORDINATES: protein motif:HMM:NF012311.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008236 - serine-type peptidase activity
                     [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="S8 family serine peptidase"
                     /protein_id="HFG9697278.1"
                     /translation="MTKVRIAVLDTGLDVNDDDINGNYVYDSNFQLKDLGGKEINDIN
                     GHGTFVSKTILNISKNTQIYPINIFNDSGKTSSLNLLSTLSKLTMSDIQIINISAASI
                     NSMYEKELEKVCNILNSQGRFIICSKHNKYEDKESIPTIFESVIGVVGNENIYKNNQY
                     IYEPENKIQMYANSKDNFIKFKDKVTHFGKNSKACAVATGIVANILKNNPYIKFNELE
                     EILIQKSKSKEDLKIENLNTPSYKSNLIRLDIARKIINVINRNFSKIKIDFEFVSEYS
                     LFNNFTCIGNYNAYNFLTILNKEFNISIDYKEVYLYQLENLDMAVDLIYENLI"
     gene            complement(41857..43101)
                     /locus_tag="ACGI5H_001569"
     CDS             complement(41857..43101)
                     /locus_tag="ACGI5H_001569"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427920.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003824 - catalytic activity [Evidence
                     IEA];
                     GO_function: GO:0051536 - iron-sulfur cluster binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="radical SAM protein"
                     /protein_id="HFG9697279.1"
                     /translation="MNSSNKYFLDCICEKIINNNQVILSNKVNGRWVKIPIECYEVLK
                     YSVDNALQLGNLYDVFQENEDKKYYERVIDKLEHIGLLSDSILSEFRLERINKISFSP
                     TNRCNLSCDYCCVDSKIDNNDYLDTSQVRKVIDNIVKLNPRILTITGGEPLMRNDFLE
                     LLDYIKEKFKGKIILSTNATLIKEKQIDDIINGLYAIEISLDGYDELSCSEVRGKGVF
                     CKVLNVIRLIKLKKFENVGLSMVVGKNNEKDIEKFNKLNEDLGTTPIIRNFMNIGRGN
                     ENYSKYLNDKLDIDYICKDDYVDESSLCSNMCKAGVNQISIDHKGDVYPCPNLEYKDL
                     KIFNILEFNENILERILNREMDIFNIFDKLKPVNIESCKECKVNLFCTTCPSKIYTLK
                     NNKKMFDANCKKMKNILEPILW"
     gene            complement(43143..45689)
                     /locus_tag="ACGI5H_001570"
     CDS             complement(43143..45689)
                     /locus_tag="ACGI5H_001570"
                     /inference="COORDINATES: protein motif:HMM:NF014717.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="FtsX-like permease family protein"
                     /protein_id="HFG9697280.1"
                     /translation="MINIKLAVSYLKRQKGKTLSLILSIGIAVMLVFSLSVINESQGQ
                     SDINHAYKNSGDYHAFYEDINSDIVKELNGEEDIKEFNDVLKFGEIISKDNGASLNLC
                     SYNKDFLDSTRYKLVKGREPRTSNELVIEQKVLDKMELDVKLNQTIDFQIVNEHINKN
                     NENSIYSKDKQFKIVGILSKSDEYYENLNKYKVRAFTYSNNGKDIVPYELITHMGTLK
                     LNTKDLDSQKVVNLGRKYKLTSNQFYPNTEVSMSMYMKNISKKTTYSIKQSLLPLLCA
                     TLVIYNMFNIIILDMTKQIGLLRAVGASKRNIRQVFFIQSIVVLSVGIVIGLLGGIVF
                     SYLGLMIVYDKSAELTINTNSIIESIIMSIIAVILASVVPIYKAGNLSIIDAIKKTDK
                     LNYIPRLLLLKSHKKVVGIINEIAFKNIFRNKVTSIIIIITISLCGVLFIGRLTSTKF
                     IYGKESDSANITSKSYGNFDIYLGYSPINANYTFSKYDNSLLNEIKAIEDVTDVEPNI
                     YLKGYLRNADLEEDYLDELKRTEINNNNESTVLIRGYNKELLNNIDKYIDKGENVYSY
                     TDRDYKNVLLVNNFYSRIKLSNNTQIIKSPKIGDLIDIKIPVYKDGEYKYINTKVRIA
                     GIMKNSYISEQDGESQSGGIQIIFNEKDLKELTGISDYNKVFVKIKKETDKKVIKEIN
                     NIIEKSGFSDIEGRYVRNHFGDHYNKSSYKLAMICVFGVLLISSINIIFIVRSNIIVR
                     LSEICTFRAIGMSKKNVKRMLIKENMIYGVLSMIVAGIISSFNYYKIVSETNKLNQQV
                     YGINNSIKFEIPIYEILIFGSISVFVCVIAVYFSNKMINKLSIVSGIKEN"
     gene            complement(45897..46058)
                     /locus_tag="ACGI5H_001571"
     CDS             complement(45897..46058)
                     /locus_tag="ACGI5H_001571"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9697281.1"
                     /translation="MIHIKKIEEKIELQDVEVQADPCKWYYDKHGIISQIDCMVDCAG
                     STPKGTVAY"
     gene            complement(46114..47130)
                     /locus_tag="ACGI5H_001572"
     CDS             complement(46114..47130)
                     /locus_tag="ACGI5H_001572"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003824 - catalytic activity [Evidence
                     IEA];
                     GO_function: GO:0051539 - 4 iron, 4 sulfur cluster binding
                     [Evidence IEA];
                     GO_function: GO:1904047 - S-adenosyl-L-methionine binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="radical SAM protein"
                     /protein_id="HFG9697282.1"
                     /translation="MKFTIFVTEDCNLRCTYCYEGNDKKKENMSYETADKTIDFICNK
                     ELESNSDYTTIVLHGGEPFINFDLIKYIHRDLVDRLSDKKILFDITTNGTIINDEIIE
                     FIAKNVKNISISIDGKKNIHDINRIDANGVGTYEKVMENGKRLIDKGIYVRARMTYNS
                     NTVKYLYESVYDIAKQGFKNIAPISDFMDKNWDNSHIKILNEQISKIMNIKKDYPDID
                     ISILDKQFINKKKGDCFGGINSYAIDTRGDVYPCTVCVGDKDILLGNIYDGLDDKKIK
                     NLIKIYISKNEECDGCTRLDYCMSTRCKLINKKVTGKFQSAVPIYCGLERVYVETTKK
                     LCSL"
     gene            complement(47127..>48203)
                     /locus_tag="ACGI5H_001573"
     CDS             complement(47127..>48203)
                     /locus_tag="ACGI5H_001573"
                     /inference="COORDINATES: protein motif:HMM:NF015983.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003824 - catalytic activity [Evidence
                     IEA];
                     GO_function: GO:0051539 - 4 iron, 4 sulfur cluster binding
                     [Evidence IEA];
                     GO_function: GO:1904047 - S-adenosyl-L-methionine binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="radical SAM protein"
                     /protein_id="HFG9697283.1"
                     /translation="DIMNKNQIFKSNNLNFDMLSNGVAIYFCLTNRCNLFCKHCCVES
                     SSNKKDLLSTYDLKNIVDIISVLNTPHIIITGGEPLIREDFFEIIKYIKQKLPDTKLI
                     LSTNGTLIDEHNVDFIITNFEKIDISIDGVDENTCSETRGKGVFNKVISSVNLLKDNG
                     FSNIKLSMVFGQKNSHLNKQFKDLNKKLGTEFVERYFIPTGRGLENKESYLIEDTVLP
                     ITIPYILDNELKMCKDKKNKKMGCCACNAGNSQIFINYDGDVYPCPSLIKDDYKMGNI
                     FDNEFVKVIKENKTRDLKSLIKLESIYPYNFEKCKDCDVNIFCWHCPAILDSVKDNEL
                     ELDRWCSMMKHNLNTAVWGDEKVN"
BASE COUNT        16136 a         7998 c         5283 g        18786 t
ORIGIN      
        1 attatatgct taaaagatag ttttgtgtct ttaaaataaa ttaaattgta tatattcctt
       61 cacataactt ttgtatatta ctaggtggtt gccatttacc atctttttta gtatatgtaa
      121 tcatagttgt aacttcctta gttggtttct tattgtaaag gtctataatc atttttgtca
      181 tatcatcttg aacttctttt tcttttttat cgtaattctt ttcatcagtt acataagatt
      241 ttactaaagt gttcgcttca ctcattactt tactagtatc taaagcttta cttacaactt
      301 tcaaagttat cttatcctta ctagaagatt ccactgttac tgtcttttca acaccttgaa
      361 ttaatttaac aattgtttcg tatatctttt cagcattttc tttaccataa agaggtgtca
      421 attgagcaat cattgaaacc ttgtccttgc tgttataagt ttgaatctgt ttatattcag
      481 cttctgttaa tgcatcagaa attccttttt catcatactt atacatttct aatgcagcta
      541 aattagcttc aaaattcgac tttacttttt cttctgcatt agaacaccct atagttagaa
      601 ctaaaactag agccataatc gtagataata ttaacttttt taccattttc atacaaacat
      661 cctccctcaa ttaaaataat aaaaaattta tttatcaaca ttataacata aatttgtcta
      721 actatagaat tattttgaat attttaccac ttccagtcta ttccaatacc gttttctttt
      781 gctttatcgt atattctttt tgctgttacg acatcttgta cacctatccc aacagtttta
      841 aatacaatta tctcatcatc atcttctctt ccaggaatag ttccgtttat aacatttcct
      901 aaatcaccac taaaatcatc tttacttatc ttaccttctt ttaatggaat taatatatct
      961 cctgactcag ataaaactgc atctgttgat tcaaaaaata tcttagacgc tctagttaaa
     1021 cagtttgggc acaactcttg catatctggc atatatgaac ctactgcact tattaaagct
     1081 ccttttttca ctaagtttcc attaagtact ggttgttttg atggagtagc taaaactatc
     1141 acatctgcgt tatctatggc ttcgtcagat gattcaactg caactatttt agtattatat
     1201 ttacttaatt ttaagttcat ttcttctgca aatttttctc tactttcctt gtttctacta
     1261 aaaactctta cctcatccaa atttctagct tctatcatgg cttcaagttg tggctcacct
     1321 tgtcctccta gacctatcaa agctccaatc ttagaatctt ttttagccaa tacgtctata
     1381 gctgctccag aggctgctcc agtacgaatc tgagttacat aagtaccatc caatactgca
     1441 ctaacttctc cagtttctcc atctaataat agtactgttg ctggaattac tggtttgcct
     1501 ttttgagcat ttttaggaaa tacagataca atttttattc ccccacagcc taattcttct
     1561 acgtatcctg gcataaataa catactagca tcttgacttg gaacagatat attggttctc
     1621 aaaggattta cactctttcc ttcacaataa attctaaaag cttccttatc agcttcaatt
     1681 gcatctctca ttgtaaatac tttttttatg tcgtcttttt ttaaaagtag catttttata
     1741 cccccaattt taataagtct ctatgctaaa tattatagca taacatttaa tttaatcttc
     1801 tatttcaaat caaataaatc tacatactct ggttttagca tagaacttat caacgcttta
     1861 tttattgaaa attctggtat tcctgctgca tatggagtta tatcatacaa atcaaaatat
     1921 acaactagat tctcatcttg caagtaaaag ttttgattct cttttatacc tttaaaatta
     1981 tatattccga tattttcttc atcctttttt tcaagttcag ctatttgtct tttaatttct
     2041 tcatctataa cttctttata tttagtatta tccttaaaca agtccattaa ttctaaaaat
     2101 tttccagttc tcatatccac attatatgct atatcttgat aaaatccatg tgctccacca
     2161 ctataagtat aatatctcac ttttatacta agagcagaat cagtattctt tttaagttca
     2221 aagtctacat ttgcaacaaa cttatttttc tcgtcaggat tatccttaag atactgcttt
     2281 gcttctttat atgatttatt ataaaattca aatatgtcat tttttatctt atcatttgta
     2341 gacctttcaa caattttatt tgaatttgtt attacaggca tgtttatagt actttctaaa
     2401 tactcatcat ttttcactat tgttttactt cctattgtac ttactgataa agtttgttta
     2461 ctatttgtat taccctttgg taatgactgg ttactcataa cagtcactgc ttccttatta
     2521 ctatttaaat taattgaagc atctttcctt aaattattat atttatagtc atgtttaatt
     2581 gccaaaacag ccattatagt caatgttaaa acaaatacat atcttaaaac tttagctttt
     2641 gtatcgactt taaaaaattt catattatca ttttcctcct aaatataaat ctctcttatt
     2701 atatttggag tttctagggt tttttatcca tataatttaa taaaagatta atttttattt
     2761 ataaaaaatt aatctttttg ttttaaaata ttaatatgtc ttatcaaaca gtttgaaatt
     2821 tcaccaagag gtaattgtaa cataacagaa cctctatcaa aagctaccat tggcattcca
     2881 tatactatac aagaattttc atcctgtcca attgtaaatg aaccattttc tttcattttt
     2941 aaaagtccac ttgctccatc ataacccata cctgtaagta ttattcctat tgaattttta
     3001 cctgctactt ctgctactga atcaaacaaa acgtctactg atggacagtg accacttatt
     3061 ctttctcctt tttcacaagt tacataatat ccttgtttat ccgtacacaa tttcatctgg
     3121 taacccccag gtgcaattaa cacatttcct tgttctactc tatcattatt cttagcttct
     3181 cttacattca taatacactg cttgtcaagc cgttgtgcat acatataagt aaatatagct
     3241 ggcatatgtt gaactacaac aatccctggt gttgattttg gtaggtcttt tataatttca
     3301 agtattgcct ctgtaccacc tacagatgcg cctatagcaa taaccatatt attaaaacgt
     3361 tccacattac cgcctccaaa aaatcatata tcaaaaatac ctttttatcg tttatatata
     3421 gcaggtttta catatttgta tttagtacta cttctgttga ttacttctgc atgtcctaca
     3481 aacaaaaaac tatctttttt ggtagcatta taaaatttat ttataagttc ttctcttgtt
     3541 tttaaatcaa aataaatcat aacatttcta caaaaaatca aatcaaaatg ttgatatgag
     3601 aaatcattca ttaaattaaa cggcttaaaa attacacttt ttctaatctt atcacaaatt
     3661 ttaaatgtac catccttgtt gtctataaaa tacttcttct tccataactc aggaacattg
     3721 ttaacatttg attctatgta tatacctctt ttagcttttt caagtgagtt agttgaaata
     3781 tctgtggcta tgattttaat gttccacaac tctttattat atccaaaata atcatccaaa
     3841 gtcatagcta ttgaatacgc ttcttctcca ctagaacatc ctgcactcca tatatttatg
     3901 tttcttattt tattattttc ttcccaaaaa ggaagtatac tattctgtat aaactcaaaa
     3961 tgttgaggtt ctctcataaa aaatgtgtgg ttagtactca atctatttat taggtttata
     4021 gcttcatttc ctgtcctatc tttaaataat agattcatat attgactaaa agaactaagt
     4081 tttttctcta tcattgtatt gtataagcga ccttcaatta acgctctttt tttacttaaa
     4141 tcaataccat attctttttt tacatggttt acaagaacta taaattcttc atctgtgagt
     4201 tttatcatgc aaaaacttcc tcctgctaat ttatcagaac taactatatg ctattaatca
     4261 aaaactttcg aatatctaaa attaatatag aattatcttc aactttcgca atctctttta
     4321 tatctttatt aatattagtg ttgttagaat tagtcgtctc tagtaaattt agattttcta
     4381 tatgaataac atcaacaact ttatctacaa taattccaac ttgatactca tcaacctttg
     4441 taattattat acaagttctc tcattataat cagctttagg aagattgtac tttatatgca
     4501 tattaataac tggtattatt cttcctctca aattaataac tccacttata tatgttggaa
     4561 gacatggtac atacgttatt gattgaaatc ttatggtttc aatcacattt tctaattcta
     4621 ttccataaat aacatcattg acataaaatg ttaatacttg tttaataatt tcatctttag
     4681 ccatacttta aatcccctaa tatatttcta taatgctatc tgcatctata attaaactta
     4741 tacttccatc cccaagtatt gtacatcccg ataaaccctt attttttata ttaaatcggt
     4801 taaaataaac tggaaatggt ttcacaacaa cttgctgatt acctattatt tcatcaacaa
     4861 aaatgcatac tgctttatgc tcattttcaa taattatcat attaccattc atcagattgg
     4921 ttacttttgt ttgaatatta tatattttat gtaaccttat aatgggaata catgctccat
     4981 atattgtaat taactctgtc ttatttcctt ctgtaattat ttgatttaag tctgtaagtt
     5041 taaatgttct tcttatggat gatattggta aagtaaatag tgaatctcca actttaaact
     5101 tcataccctc tactatagaa agagttaatg gtatttttat agtaaaggtt gtcccctcat
     5161 cctgtttact ttttacttca attgaacctc caactttttc aatactttta cgaacaatgt
     5221 ccatgcctac tcctcttcca gaaaattcag ttatagattc ttttgtagaa aagcctggag
     5281 tcataatcaa agaattgacc tcgtcatcag tatactcatt actttgatgt ttaagaagac
     5341 cttgttcctt agcttttgcc aaaatcttat ctctcataat gcctctacca tcatctgaaa
     5401 tacttatcac agcttctccg cctagatttt cagcagataa aactatcttt cccacttctt
     5461 ctttaccttt cgctatacgc tcctcaatag gctctattgc atggtccata gcatttctta
     5521 taaggtgcat aaaaggttcc gctaaattat caattacact cttatccacc tctgtttctg
     5581 ctcctatagt tattaactct acatttttat ctaatttttt attcatatct cgtacaattc
     5641 tatgcatttt ttgaaataca ccagcaattt gaatcatacg catagacatt actatatctt
     5701 gcaattcatc tgtaagcttg tgtaattgtc ttgttgcctt attgaaatta tctatatcaa
     5761 cacctgtaga atttacgcta tttacaacca ttgattccat aattacaatt tctccaacta
     5821 tattttgaag taagtccaat ttttctaaat ttacactcat aatactctgc ttacttattg
     5881 gtaaatgttc attttcttca cttagactat ctttttccat atcagttttt tcatttaaaa
     5941 catcttcttg tatctcatct tctgtatagt tattttgata acttttactt actttattat
     6001 tatcttttaa tttattttct actgcatcat tgtttgatgt acttttcatt tctatttctt
     6061 ttttactaat atttatgtat tcttttacat agagattatc ttctatagtt ttataaacta
     6121 ttgccttatc ctctttagct acaaattgta tataaaaccc ataactttta atatactctg
     6181 tagactctgc atttgtttct acatcttttg gataaaaatc tataaattca cagtaatctc
     6241 taagttcaaa tacaagcatg aaagctctca cattttccat catgcaacct tgttcaaaga
     6301 ttatttttac tacatcagag tcttctttgt attcaaaatt tgaatcgatt acttcttttt
     6361 cgtctttact ttctaaattt gcattatcct ttgatttcat agaacttgat aattccaaag
     6421 tactcacata ctcttcaatt ccttcaataa aattagagta atcagaagat atacaacctc
     6481 ttgattgtaa ctcatctata tctcttctta taaaatctaa tgattgaaag actaaatcaa
     6541 ataataggtc attgtctaaa acttctattt taccttcacg tatagcataa aacaagtctt
     6601 ctacactatg tgctaaagca gatatattgt ctaaccccat catagatgct gaacctttta
     6661 tcgtatgcat tattctaaaa gtttcattaa tgttgttatg agtaaatact ttctcttttt
     6721 ctatttgaat cataatttca tctaattgtt cgagtaataa acttgtctca aatataaaca
     6781 tatctaacat ttgtctcata ctcggttcaa tataattcac atttatcacc tacgacctac
     6841 aaataatttt ctattatata tgcatctcat aatttaaatc cttgatgatt ctcttatctc
     6901 actatatgta cctcataatt taaatacaca attattctct tacttcaata tatatacatc
     6961 tcataattta aatccttgat aattctctta tttcaatata tatacatctc ataatttaaa
     7021 tccttgataa ttctcttact tcaatattca cctcataatt taaacccatg atgattctct
     7081 tacttcactt tcctttagat gaaatttttc tactaattct tttaaaattt gagcctgagc
     7141 agacatctct tctgaggctg ctgcactttc ctctgctgtt gctgagttca tttggactac
     7201 tatggaaatt tgctctattc cagataaaat ctgtgtaatt gctacttctt gactatgtac
     7261 agccgaagaa ataccattaa tataattagt agttttttct acaccattta ctaccaagtc
     7321 caatgcattt gcagtctctt tagcaattct gacaccattt tctactgttt taatagcttc
     7381 ttctatgaga atagctgtat tttgagctgc ttttgcactt ttaccagcca aagacctaac
     7441 ttcatctgct acaactgcaa atcctctacc atattgacct gctcttgctg cttcaacagc
     7501 tgcatttaat gcaagaatat tagtttggaa tgctatctca tctattgttt tgattatttt
     7561 tgatatttca ctcgattttt cacttatttc acccattgat gtcatcatat catccataca
     7621 tctacttcca aaaccaactt gtgatgcaga ttggtcagat acctcacatg caagactagc
     7681 actatctgca cacttcttaa ttccatctga tatctcatta atcgtggaag ctaattcttc
     7741 tactgaacta gcttgttcag tagcaccctg tgaaagagct tgtgcacctg ctgcaacttg
     7801 ttctgaagca cttgcaactt gctctgctga taaatttatt tcagaaaaat caccattaaa
     7861 agagtttatt atactttcta aagatatttt aattgattta aaatcaccta taaattcttg
     7921 gtctatctct actcttaaat ctccttttgc aatactagtt aatgtactgt ctataaggtc
     7981 tatgtaattt aaaagcatac tttgcatctt tttgacagaa ctcactaata gccctatttc
     8041 agatttactt tcttcaacgt ctatacttgt tcttaagtcc ccagatgcaa ttcttgaaaa
     8101 gtgtttttct actttattaa taggaatcac tatttttaat tttattactg tatattctat
     8161 tattgtcaat attattaaaa gggaaagtat aaatattgtt cttaatatta gactttgtaa
     8221 ttcttttttt acttctacaa ttttggaatt tgaacgggta actatatcct cttgaaattc
     8281 atttattaaa gaatccattt tctcttggga gtttatatag tcactaccaa aaattatact
     8341 ttgagcttta ctcttatcat tactttcgac tgcctttatt gcactttgtt ctgttggtac
     8401 taaagaatct gatatttctt ttgcttctaa gattttattt gactcgctct ttgtaagacc
     8461 aattttttct aatttgttta aagctgattc tcttgttttt ccgtataatt ctttttcata
     8521 aatatcttta ttcttttttt ctcctgtaaa tacatatctt cttaatacat cacttatctc
     8581 tctagttgta tcttttatat actgactttg agtcctcaaa ttattcatat cattaatact
     8641 tttttctact ttttcaaatg ctttataaga tgaaatagaa gaaaaaatcc ctgctagaac
     8701 agccaatact ataataatca gcaatacaat tgctaattta gaaagcttta cttctctttt
     8761 catatctgta ctccttcata aagtaagttt atatcttttt taatcctttc attgtactca
     8821 ctacgctaca atcttttcct aagtttttac cctcatacat tgctttatct gctaaggata
     8881 tgttttcttc taatgatata tttgagttta cttctactac tcctaatgta atagtgcact
     8941 ttattttatg ttctttatag ttgaaatcaa actcctttat ctctttacgg attctttctg
     9001 aaagtatctt agcaccttct attggagtat ttgtgagcat tatcaaaaac tcttctccac
     9061 cccatcttga tacagtatca atttgtctac aattcttttt tattatactt gatattactg
     9121 ttaacacgaa atcccctgct tcatgcccat aagtatcatt gataacctta aagtcatcaa
     9181 tatcaccaag gataagggat attgatgttt cactatattt attaattctt ctttgctcca
     9241 taagctgatt aattatatgt cgcctattgt aaagacctgt aagataatct cttacaacga
     9301 gtctattcaa tttttcaaga gaagattcca gttcattatt tatctttttt aatttatctt
     9361 gagatttctt tacttcaaga tgagctataa cacgagcttt taattctgtc atactaaaag
     9421 gtttcaccat atagtcaatt gctcctacac caaatccttt tactatgtct gtatctgtat
     9481 tttttgaagt tataaaaatt ataggtatat ctgctgtacg agcattagat tttacttcct
     9541 tacaaaactc aaaaccagag ttatctggta aaattatatc aagcaaaata atgtctggta
     9601 taaattcttc aataaattct tttgcctcta ttgcattaaa tgctttttta accttaaaat
     9661 tatcttttgt aagtgtttta tctattaagt cacacatcag aacactatca tcaacgacta
     9721 aaattgttcc ctgttgctta tttttcatat acaaacctct cttaaacata atatattcaa
     9781 attttaatga tttaaaattt ttatacttaa taattatacc actatattct taaatgttct
     9841 catcacaatc tttttataat aacactccaa ctacatccct atgttacatg atagtgcaat
     9901 caaacccatt gattaattca tctattaaaa cttcatcttt atctgtcaaa agtttctcca
     9961 aatctagtaa agtaattatt ttaccttcta attctccaac tccacttaca aaataatccg
    10021 aatattctat agtaactctt ggtggaggtg atattttact tttttctaag cttactatat
    10081 catcaactct atcaaccaca aatccaacta ccaagtcctt tatttcagtt actactatat
    10141 acatgcaatt tgtagtcatt aattcatctt ttttaagtct caaacgcata tctattatcg
    10201 gaatgatttt tcctcttaga tttattatgc ctttagaata tgtaggtagt tctggaataa
    10261 atataatttc ttgatttcca gtaatttcta ttaccttttc aagttcaacc ccaaaatctt
    10321 gctcatctac tttaaacttt agatacttaa ttccttcatc aattagtcca taatctaaat
    10381 atgggtcatc tggaaatctc atttaatacc tccctcctaa aatacacttt ctatgaaata
    10441 tatattataa tttcttctta cctttattta ttgaatctac aagtaattca cccgtctcag
    10501 tgtaaaaacg tattgttcta ccataattca tacctgtgtc ctcagctaat attggaatat
    10561 ttaatcctaa aagagttttt tttactgcct caacattcct atgtcctata cttgcaatta
    10621 ctgaattgct acttcctaaa aacatctgag cacctccagc aatttttgct tttatatata
    10681 ttctatttgc acctatattc tccatagatt taatgagctc atttattcct gtgtcagcaa
    10741 atttacactt attttcaatg ttaatagcat ctttactata tggcaacata acgtgtaaca
    10801 ttccaccaat tccagctact ttatctatca aacatactcc tacacaagaa ccaagtgcat
    10861 aagtaactaa aacatttggt ctataggcta tcttcatatc tgcaatgttc actactatct
    10921 ctctattcat acttctaatc ccaacctcac gagtatttct ctaagtgagc tcatttctgg
    10981 aatcatcaaa atgtgactag taaaataatt atcactcatt ttaaatttat tttctataaa
    11041 taagactttg tcaccaacat ctgaaaatct tatcataggt acatttagaa cagctccaac
    11101 catatcaata catatatctg gaattgaaac acttatagtc atgtttaaca tagatgcaat
    11161 agcatttaca tatgaacttg ccataatatt tcctatttcc ttaattgctg aaatttcaat
    11221 tgcctcaatc tcatctaaaa aagcttcttc tttattaaaa agagaactta gcataagttg
    11281 agttattgat tcatccaaca aaaacataaa cattccattg atatcacctt tcatatcgag
    11341 taaaatacat actactttgt tttctggacc accaagcaaa tttgtcgctt cattatattc
    11401 aagtatcttg accataggta ttaatacttc tacattgcta tttatcatgg atgcaagtgc
    11461 agtaattgca ttcccagagc ctatattacc aatttctcta agagcatcta tatgaacatc
    11521 atcaagttct aaataattta taatataaac ccctcccttt attattgcat ttatttgctt
    11581 ttcattgtat tagtgtatat ttacactttt attttaaagc attatctaca actttaacta
    11641 atgtttctgt tttgaagggc ttcactataa aatctaacgc tccaagtttt atggcttcta
    11701 caatcatatt ctcttgtcct attgcagagc acattacaac cttagcactt gaatccaact
    11761 tttttatttc tcttagcacc tctaaaccat ctttttttgg cattgtaata tcaagcaaca
    11821 tcaaatcagg cttttcatat ttaaatatat tacacgcttc ttctccatca tttgcttcta
    11881 ttaaattatt atagccactt ttactcagag cttctttaat tatcattctc ataaaaatag
    11941 catcatctac tatcaaaatt ttattttcca taaaactaac tcctccatat gtacaacaat
    12001 aaacgctttt atcttcagtt attgtctata ctatctgact atttttcgct acacaataaa
    12061 tacatttcat tgataaataa aagtaattat ttatgccata ttatacttaa ttctcttaac
    12121 ataatttgtc aacaaaaaaa cttatatatc tattgtaata tatgtttggc gttttgacga
    12181 gttattaaaa atataattgt ataaaacata aaaagttatc aaaagtaatt aaattataat
    12241 aaaacaactt tatacctttt ttatgtttgt ataaaaaaaa ttttcagatt cattaaaatc
    12301 atttctgtag attcatatag gatttgactt tctcaatatc taatagatag ttgtttattt
    12361 acttaattat atttctctat atgtattatc gattaaatta gatttagctt tatacattat
    12421 tttttatatt tttcaaattg tatactcata aatccagaag tattctaatg tgtttataat
    12481 actttttttc atattttaaa ttaaataaca aatcattata tttacaagta tcatttatca
    12541 ataaacaata ttaaatgaag aatatgtctg aagattcaaa gtgatactga tactattaat
    12601 tactaaaaaa gcagtaaatc ttttacagat ttactgctta tagttataaa taataaaact
    12661 atctataata aatgtactat actcaatatt tcattcaata tagtaataac aaatctactt
    12721 tattcctatg taaatatgaa tttcttgttt ctttgtatca aaagtattac attgatactc
    12781 ttcaaaatca cttatataag tcctatcaaa atccatttgc caaaactcaa accaaaaatc
    12841 tcctacttct ttttgacctc ctactataac aaactttgca tacttacctg ctggtataac
    12901 tttactaata atactttctc caacagtatt attagtgttt aattcttcta aattcttctc
    12961 tttatcagaa ttactattta cttcacaaca tgcaacaaag ctatacggac ttgtaaaatc
    13021 accctggtaa tctgtatata gacctattgt cttgtcattc tttttaccct ttatagcatt
    13081 atatatccct ttgcccataa attttttcca caattcacct atatcattta ccgcttgtcc
    13141 atctttattt gtagtctcct tcgatattcc tataactatt ttctcattta tctctactat
    13201 ttcataattc atactttata cctcactttg tttttattaa tctattttat tttgaactaa
    13261 ttcaattata atttataata tacgacacct ttatgtcata tttttaatat aattaaactc
    13321 agtgagatat tatatactaa atgcaagata ttatatattt aataaaatct ttaatctagc
    13381 attatattat aatgaataaa ttttagacaa ctcccttagt ctagttatta cattatccct
    13441 aacatcttta ggttcaagta cttcaacatt gtcaccaaat gataaaatat atccataaat
    13501 ccattcacca ataggaaatt ctgtaattac atcatatgta tcatcttcat ttttagttat
    13561 taaatcctta ttaaaatcat caaatactct aaaaagcatc ttttctttaa acctcaattt
    13621 caacgttata gtattttcct taattacttt agaatcattc aaacatactt cttctattat
    13681 ctttcttgaa aatacttcat cctttataga taaattcctt atcctactaa ttctaaatat
    13741 cctaaaatca tcttttagtt tacaaaatcc atacaagtac caagtcttac tcttatacat
    13801 aagcttcagt ggttcgacag ttctgtttgt ctggcttgac aaactattta cataattaaa
    13861 atttatagta ttacgcctta aaatagcttc ttttattttt gtaaatttat catcttcatt
    13921 aaaattactt ccccattcag taaagtctat ttcaatccag tttgaaaaat tctgctctcc
    13981 aaatattgag ccaattttat ttactactga atttatttct ggatacttag tcgcctgtaa
    14041 tgttttcagt gcaactatta aactctcttt atcttttttt gacaatatag ccttgtctat
    14101 agaatattct tctattaaag atatccctcc tcctttgcct ttcgtcatat atactggtac
    14161 tcccgacata gacagagttt ctatatctct atatatggtt cttgtagaaa cttcaaatct
    14221 atctgccaac tctttagctg ttactaattt tttatttaat agaattacta ttatttctgt
    14281 taatctattt attttcattc attaccacct actaaaatta ttaaatttat ttaatctaaa
    14341 ttaatcatac taatttttaa ataaataaaa tcttagaatc ttatctaaat tatttttaca
    14401 tgattttatt tactttctat tatctttctc actttggata ttatcatctt aatttattta
    14461 ttactatatc aatttactta ttatcatctc atttgttatc gtcttactta atttacttat
    14521 ttctatatca attcacttat tattacctca cttgttatca tcttacttaa tttacttatt
    14581 tctatatcaa tttacttatt atcatctcat ttgttatcgt cttacttaat ttacttattg
    14641 ctatgtcaat tcatttatta ttatctcact tgttatcgtc ttacttaatt tacttatttc
    14701 tatatcaatt cacttattat catcttaatt catttgctta ttatcattta ctttattcaa
    14761 tttctatatc aaaattagta tttgtactta atacttaaaa ttaatttaaa gtctttacat
    14821 attatttatt ttctattgta atattcattt ccatacttta ctaagctact tccactcatt
    14881 tattttaaaa tttcaattta ctatttctca actctatatt attatttttc aattttatat
    14941 tactaatttt aaagcttttt agctattatt cctacaatat ttaaacaatt ttttcataat
    15001 aaagctatat tacaatatat tcaaaatatg taatatttta gatatttttc gttgacaatg
    15061 ttaaattttt gttttatcct taattaagga catgttattg acatttctga aacttatttg
    15121 aaatagtttt ttcattttat ttaggaaaac gtattatact taagaaaacg tattttctca
    15181 tttcagataa gtaaaatatt tattcttttg gggaggaaat catggaaatt aataaaaaac
    15241 attttattca agtattttta acttgcttaa tcttggtagt aatatgtgaa tttatagggc
    15301 aaagaactat agctattgga aaagcctcta tagtactgtt ccctatgctt tatgcagtta
    15361 taattggact tataataaca ccagatttat taggtaaaaa aattaaagca cttaaaaaag
    15421 tggttggaga aaaagaaata aatattgctg gtgaagttgt tggaattgca ctagtaatgc
    15481 ttggtataaa atatggtact acagttggac caaacattga caaaataatt caagctggac
    15541 cagcgtttat cgctcaagaa tttggtcata tacttgcacc aatcgttgca ttacctcttg
    15601 cattaatgtt tggaatgaaa agagaagctg ttggagctac tgcaagtata agtcgtgaac
    15661 cttctttagg agttatatca gaaaaatatg ggataaactc accagaaggt agtggtgtac
    15721 ttggtacata tttaatggga acagttcttg gtactatata ctttagtgta ctaggttcaa
    15781 tatctattta tagtggtctt cacccatatg ctttgggaat ggcctgtggt gttggtagtg
    15841 gaagtatgat gacagcagct gctggttcat tatctaccat ggtaccacct gaaatggcag
    15901 atacaatact tgcctatgct gcaacaagca atatgatgtc tagtataaca ggaattatat
    15961 tcttagtttt tgtatcctta ccatttacta attttatgta taagatttta gaacctaaat
    16021 tttcgagaaa taaaaaaact aaagaaatta aatctacaga aggagagtgc taataaatgt
    16081 ttgctaattt aaatttaaag aaaagttcat atcaattatt ggttatgtct gttattggag
    16141 ttataattct tataggacaa agaattagcg ttggtacatc tatagttaca gctcttcctg
    16201 gtatggtgat gctaatatta gctgctatgg cagctatgat tataaaagat ttatttccta
    16261 aatcaatctt tccagctttt ggatttgcaa ctataatcgg ccttttactt agtatgccat
    16321 atagtccaac atctgaagta ttcttaacta acactaataa tattaacttt atggctataa
    16381 ctactccact actagctttt gcaggaattt ctgttggaaa caaaatagaa gctttaaaag
    16441 aaatgtcatg gaaaatagtt ataatttcac ttattgtatt tacaactata ttctttgcat
    16501 gtgcgagtat agctcatata gttttaagta ttcaaggtaa aatataggag gaatttatta
    16561 tgaataaaga acaattaaaa tctctagtaa taaaaactat agatgaaaat agagaaaaaa
    16621 tattaaaaat aggtcaagga atatacaaaa atccagaata tggatataaa gaatttaaaa
    16681 ctacagaagc tgtttcaaac ttttttgagc aagaattaaa tttatctgta gaaaaaaata
    16741 tagcagttac aggatgcaaa gcagatgcaa attctagcaa gaaaggtcct catatatcta
    16801 tacttggaga attggatggt atatcatgta aagaacataa agatgctaat gaaataggtg
    16861 cttctcatac ttgtggacat aatattcaaa tagctggaat gttaggtgct gctgttggtt
    16921 tagtaaaaag tggcgtttta gaacatttag atggtaaagt atcttttatg gctactcctg
    16981 ctgaagagtt tattgagttg gaatacagag agcaattaaa aaaagaagga aaaataactt
    17041 attttggtgg aaaacaagaa ttaataaaaa gaggttattt tgatgatata gacatatcta
    17101 tgatgtttca tgcttctgat ttaggagaag ataaggctct agttggtcct gagagtaatg
    17161 gatttgttgg aaaaaaggtt aaatttatag gtaaagaatc tcatgctggt tctgctccac
    17221 atgatggaat aaatgcttta aatgcagcaa tgcttgctat aaacaacgtg aatgcactta
    17281 gagaaacttt taaagagtct gaaagagtta gattccaccc tatcatcaca aaaggtggag
    17341 atatagtaaa tgttgttcct gctgatgttc atatggaatc atatgttaga gctagaacta
    17401 taaatggtat gattgatgct aatgaaagaa taaataaggc tttgatggct ggtggaatgg
    17461 cagttggagc tgatgttgag ataactgaaa ttcctggata tcttccaata ttacgataca
    17521 aaagtcttga taatttattt aaaaacaatc ttgaagattt aggtctaaaa ggaaaagtta
    17581 ttgatggtgg agattttaca ggctcttttg attttggaga tgtgtctcat ataatgccta
    17641 ctcttcaccc tatgattggt ggtgtaaaag gagctcttca tacaagagat tttgaaatag
    17701 ttgatgaaga tttagcttac ataattcctg ctaaagcaat ggcacttaca gttgtagacc
    17761 ttctttttga taatgctaag gatgctaaag atatattaga tacctttact ccagttatga
    17821 ctaaagaaga atatctaaca ttcttagaaa aacacgataa aactttataa gtctattttt
    17881 ataatagggt ggtatctact gtaaaagtta taccactctt tgtttttgta acagtatact
    17941 tcttttcttt tagtttttag attaaactaa aatatattat cctccttaaa acttttagag
    18001 ctacgttgaa atatcagtag aactatgcta tattctttct aattaatata aatttctatt
    18061 ctaattcaag gtggtgaaaa aatgtttaat gcaggaaatc gaattataaa tacatggttg
    18121 taccctattc aagatggctt tgtcttgatt gatactggat atgaaaatgg ttttaaacat
    18181 ttcaaaaaac gaatttctaa attcaacata aaaatcaaag atattcgata catatttcta
    18241 actcatgctc atgatgacca tgttggtttt ctaaatcaga ttctagacga atctcctaat
    18301 acaaagattg ttatgcatga taaagcttta gaaattctat ataaaggtca aaactctttt
    18361 attggtggtt gtaccagccg tactgccttt ctcttttgcc aaattatgaa actatttgga
    18421 aaaggtgagc atagtttttc tccacttaaa caagaatttg aaaaaaggtg tattcttgtg
    18481 tctgacaaga atcgtaaaga aattgaaaaa gaactaaatg gaaaaattat agatacacca
    18541 ggacatactg atgattcaat ttcactacta attgatgaag gtgttttatt ttgtggagat
    18601 tctgcaatga atggatttcc aagtactcac aaaattacca tatttgcaga aagcaaacta
    18661 gaatttattc aatcttggaa aacaatcatc aatacaaaac ctaaaatgat ttatcctgga
    18721 catggaaaac catttgaata cagtaaatta gaacaaaatc taatctatgt aaataaaata
    18781 aatttatatc ctctacataa ttcaaaagat attcacagat ttttgtagaa aatacaaagt
    18841 aaatttattt gattaattaa aaaatctaac actttactac gctacttatt ttaataactt
    18901 aatcttccac tagcttttca taaaattttg ttttaaaatt aattttaaag tgcatatgtt
    18961 atttaaatac attagataaa attcgtcatt aatctactta aagcatattt aactaacacc
    19021 actcaaccag aaaattcaga aaactgcatt gacacaggaa aaagtttatt ttatactttt
    19081 tttaggacat attgtggaca cgtcttaaat cgacaaacag aatttaaatt gtaagattaa
    19141 ccacaatact tattttttaa ttatattttt aaacattagg gaggatatta tgaatgataa
    19201 cgtagttaag aagaaaaact tttttgacag gacattaaac agaatagaaa ctgttggtaa
    19261 taaactacca gacccagtta caatattttt agggttatgt gtacttttac ttatactatc
    19321 tagtctagtt ggttctatgg gtatatcagt agttcatcct ggtactggag aaactataac
    19381 cgctgtaaat ttattgactg tagaacagct tcaaattctt ttaggaaaca tagtcagcaa
    19441 tttccaaggg tttgctcctt tgggtctagt tctagtaact atgataggtg ctggtgtatg
    19501 tgacaaaaca ggacttatga cagcaacaat caaagcatca gtaagcaaga ttcctgaaac
    19561 aagagtaact cttgttgtaa tgactatagg tatgcttgcc aatatagctt cagatgcagg
    19621 tacaatatta tttccaccat tagctgcact tgtatatctt ggtgttggta gacatccact
    19681 tataggttta ttttctggat atgcagcagt ctgtctagga tttgccgcaa acattatgat
    19741 aagtgtcaat gatatacttg ctgcaagttt tacagttcca gcagctcaaa tgattgattc
    19801 tggatttcaa gccaatgcaa caatgaactt attttttatg atagcatcaa cttttgttct
    19861 aatacttttg gcaacatggg taacagaaaa aattgtagct cctagatttg gtaaatatga
    19921 aggaaatgca gaactagatg ttgatggaag tcttagtgat gtagaaaaga aagggcttaa
    19981 aaaagctagt ataagtatat taatatatgt ggctattata gtagctctta gtgtaatcgg
    20041 taaaaaacca ttcttagctg acccagaaac aggagattta ctatcaaaca atgctcctct
    20101 tatgaaaggt atggtaccta taatagcact agcatttttc atacctggtg ttgtatacgg
    20161 aaaaactata ggtaaaataa agaaggataa ggatgtagtc tctataatgg ctagtgcaat
    20221 gagtgatatg ggtggatata taatactagc atttgctgct tcacaatttt tgcaattatt
    20281 cacaaatagt aatttaggtc tgatactagc tgtaaagggc ggagaatttt taaaatcagc
    20341 aggaataaat ggacctttat tgttgatagg atttattata ttatcatgtt ttataaattt
    20401 atttataggt agtgcatctg caaagtgggc tattcttgca cctatatttg taccaatgtt
    20461 tatgatggtt ggatacaatc cagcacttac tcagatggct tatcgtatag gtgattgtat
    20521 aacaaatcca cttagcccat tatttccgta cttccctatt atactagcat tcacaagaaa
    20581 atacgataaa gatgctggta tgggtactgt aattgctaat atgataccat actctatatc
    20641 attcttaata gtgtggacta tactattaat attgtttatg gtatttaata ttccactagg
    20701 acctggaata cttccttcat atagcatgta atttatttaa atctttctaa aaggagaaat
    20761 aatttatgtt agataaaaat agacttataa ataattttat ggatatggtt agaattgata
    20821 gcccatctaa tcaagaatta gaaatgtcta agtggttggt aaactactta aaagaaagaa
    20881 atatagatgc cattatagat gatgcaggtg aaaaatatgg tggtaataca ggtaatgtca
    20941 ttgcctatat aaaaggtgaa gaaggaagta gaccactttg tttatgtgca cacatggacc
    21001 aagttcaacc ttgtttaggt gtaaaaccaa tactagatgg taatgtagtt agaagtgatg
    21061 gaactactac acttggtgca gatgataaag ctggaatagc tgctatactt gaagctttag
    21121 aacatgttat tacagaaaaa ataccacata gagatattta tctttgtttt acaatctgtg
    21181 aggaagctgg tatgcatggt gtcaaaaact ttaatcctga caacttgcct tgtaaagata
    21241 tggtgatttt agattctggt ggagctattg gttcgatagc atacaaagct cctgctcaac
    21301 aatctataaa aatctctttt caaggaaaga aagcacatgc tggtatagaa cctgaaaaag
    21361 ggttaaatgc tatattagta gcctctcatg caataagcaa catgcacata ggcagaatag
    21421 attcattgac tacttcaaat ataggtgaaa tagaaggtgg tggagctaca aacatagtaa
    21481 ctgataaggt tacattgact gctgaaatta ggtctcatat acctgaaact ttagagtatg
    21541 agcttaatca tatggaaaaa tgttgtaagg acgctgcatc taaatttaat actacttata
    21601 cttttgaaca taatatgtct taccctagtt ttgaacttag tagagatagt catgttttca
    21661 agttaagtga agaagcaata agacaagttg gtgttgttcc aaatccaatg gtaattggtg
    21721 gtggaagtga cgcaaatata ttagctaatc ttggatataa ttgtgctata ttaagtctag
    21781 gtatgtatga tgtacacaca gttaatgaat atgtaaatat agacgaatta tatgatactg
    21841 ccaaaatagt ttatcatatg attaaattat aaatatcata atagaactct ttaaattata
    21901 aaaataaaaa cctatgtatc ctcaacttta taagttatat attagagttg ttttacatag
    21961 gttttagtat ttttatataa taatttgttt taacattttt cataataagc tttgatattt
    22021 tatatagtaa tttgttctaa catttttcat aataagcttc aatattttgc ataataattt
    22081 attctagcat ttttaataat aggctctagt attttatatt aataatttat tctagtattt
    22141 tacataatta tttgttctaa tttttttcat aataagcttt aatactttat atagtaattt
    22201 gttgtagaat tttatacaat ataatgattt atacagtttt ataaaatatc ttaaaacagt
    22261 atttcagtaa tattttttgg tcttcctcca ccaatactag tctcttttgc acatattcga
    22321 cctaaacctg catttactat tttatttaat atacgtcttg cacttctttc acttacattt
    22381 agatactctg ctaactcttt tgaatcataa atcttacttt ttctattctc atttatagca
    22441 ataatttttg caactgactc acaactcatt ccagtctttt tagatatttc gattaccttt
    22501 tcatcagata gcatcaaaga ataatttaat tcattttcgg aagctaaagg tcctcttatg
    22561 ttttcatctt catctaccaa atatatacca atttcttttg aatctatgga gtgtcttaat
    22621 gctttatgtg cattattttc agcctgatac gcagttactc cagtaccaat tcctatacta
    22681 agagaaaagc ccatgtcttt tatctctctc tttagattga atagcttatc ataattatac
    22741 tcattatcag ctaccccttt atgaacaaat acaacataat catttcttcc aagtaaaaat
    22801 aaggaacctt gaatgcttct tacatagttt actacaagct tatccatatc tgattttttt
    22861 atcatgtcag aataatagtt atctatcttc tctttataat ctattaaact caatatttca
    22921 acagcaattt gggaaaatct tgccttactt agagcatatt cactctttac cttgtcataa
    22981 ctttctttga ttaattgtat agtagcttgt aaacgaaata caggatagcc tctttctttt
    23041 aattcattat atactgcacc aaaaccagtc aacattatat ccgtcttatt ttcttcaaat
    23101 aattttatat gccattctac aagttcagac tctcctactt ccaaagaaaa tggattacaa
    23161 aatacactcg ttgctttaat atcaaattct ttaagtgcat cttccacaac atatctatca
    23221 actacatcta tactgaattt atctaatttt atatttgcac tttttattgc ccaaaatgcc
    23281 ttcattatac tcgtcccact tctcggtaca aatgaatgtg gcttacttat ctcatactta
    23341 gattttataa attcataaac tgcacatcct gtaaatataa tagcatcaca ttcgtcttca
    23401 catttagaaa taacttctat tgtatctact actttttctc ttacatatat tttagtcttt
    23461 aaatcactgt ctatctgttt taaatcatcc tttatcttaa acccagagtc tgaaggacct
    23521 ataataccca ctatcataaa cttcgctcct aatccataaa tattatactt tttaaaaatt
    23581 atatcctcac tattttctac ttctatttaa ttattttgaa ctactccatc ctacctacat
    23641 ttagaatgga ataattagct tatttttgat aaagtaactt ctcaaaatca gcacttggaa
    23701 taggcttaca ataataataa ccttgaatta ccacacaatc taaagtcact aaaaattcag
    23761 cttgttcttt tgtctctaca ccttctgcca ctacatccat atctaaatct tttgccatgg
    23821 ctatagtgtg ctttaaaact attttttctc tgtctgtgat tccttcctca ttaaagaaac
    23881 cacaatctat ctttaatgta tcaatattaa tattttttaa catatttaat gaagaatatg
    23941 ctgaaccaaa gtcatccata tttaaaacaa taccatccat tctaaggtcg gctattatct
    24001 tagtaaataa ttttatattt ttaataaata aactttctgt aagctctaat tctaaaaaag
    24061 attttggtat actatattta tttattaaac ttaaaacaat ttctttaaaa tgtggattat
    24121 gcaaatgtaa tcttgataca tttacagaga taggaactgg ctcttcacct aaatctatcc
    24181 attttctaat caaagaacat acttgttccc atacatacat atctaatctg ataataaacc
    24241 cattcttctc aaatagtgaa ataaatttaa ttggaggtat tatacctttt tctggatgaa
    24301 cccatctaac caatgcttct gcaccaacaa ttttatttgc attaagatta tacttaggtt
    24361 gtaaatatac atggaattgc ccattttcaa gtgcgtattc catttccctt tccatctgtt
    24421 tttcttcaag tgcatcattt cttatagtat catcataaaa tatatagtta ttgatacttt
    24481 gtttctttac ttttttgtga gcatatcctg ccatttcaca cgcatttgta attggaatat
    24541 gattatccaa aattctataa accccaaaac atggtactaa catatattca aatttttttc
    24601 tatttaagct atttttaatc ttataaatta ccttatgaat atctctatca gagtaactct
    24661 cataaaaaat gcaaaataca tctgcataca tacgacaaca tataccatta gaaccaatgt
    24721 ttttttgaat caactctgca acatatatta aagctttatc tcctcctcta actccataaa
    24781 tgtcattaat taccttgaac ttatctatat ccatcattat aattgcataa cgcttgtcag
    24841 gatatctttt aagcattaaa cttatttgtt cacaaaaact ttcataattg tatagtcctg
    24901 ttaatgtatc tttttggttt ttatgtagtt gcataagata atctatattt tttatagcaa
    24961 ctaaaatatg tgtttgtttc tcacctaact tatttttact actaatcttt aacatataaa
    25021 ttaatgccca atagtacttt ttatctattc ctaaacgtct atactcaaaa tttagttcta
    25081 aatcgtcttg cttgctatta ttaagactat caagagattt tagaaggtgg ttatcattaa
    25141 ataatattat atcatcagga tgaattaaat gtttttttat gtatgaaaaa gttttttcaa
    25201 gattttcctt tataggaaaa ctaaaaatat tgctctctga ttgataaatt ggagtaatta
    25261 aattcgtatc aatgcaaata gataaaatta tatcatatgt attataagct aatttttcat
    25321 aagccttaga ataccctttt atcattaaat catcaaaata aaccttatca actaactctt
    25381 tatgtttaaa taaaatatta ttcgtcgaat cagctaagtc actaattact ttcatttcat
    25441 tatttctaag tttgttctta ttataatacc tcttcttatc ttggtacatt ctctcatcag
    25501 caactttaat tagcttatgt atatcaatat tatcgtcact ccaaatactg cccactgcta
    25561 cactatatat catctcatcc ttaaattctt cacttaacca actcactaat tcttcaaata
    25621 gttgttttga tatatcttca cataatacaa caaactcatc tcctccaata cggtaaacat
    25681 tataagaatg aaagtatttt tttattatta cacatgctga cacaatagca gaatcgccat
    25741 tagcatgtcc aaagttatca ttaatatctt ttaacccatt tatatctaca aatacaactc
    25801 ctatggattt aacttttcct ttttgaaaat tatctatata cttaatatat ttatttctat
    25861 tatatgcacc agtcaagaag tcatagtagc tcatataatt taatttattt tctacttttc
    25921 tttttttcat ctcagttaat aaaaaataag atagggatgt caaaagagag gtatctccaa
    25981 cagctttatg tggattatca actccaataa accctactac tttatcatct tgttttagtg
    26041 aagatgtcat taaactttca attttttgag gttttaaaat ttcatattct attggctgtt
    26101 cttcttttat attttctata tcatcaatta ttacaaaacc tttttgttcg aataataaaa
    26161 accaattctt taattcatta atatcaagat ttgttagtgc ctgtttttgt tcatcaacac
    26221 cttcattgca ccattcatat gtattagtta ctttttttct atcttctgat acttcaaaaa
    26281 catatgctct atcagcttta tgaaatttac caatattggt taatacaaga tttacagcat
    26341 cagaaaaatt agattctgtt ataagatgtt taatacatcc aactaataac tcctttatct
    26401 ctaatttttc tgctattgac ttacttatat cttccttttc tgtaatatca agagctattt
    26461 ctaatcgtgc atgtttgccc tcccatttaa ttaacttgtc ctttaatata aaatgtctat
    26521 ttgttcgagt attcgtattt tcccatatgt aatattcatc ttcttttaaa atagagtttg
    26581 tacaaaattc gcagggagaa tctttcccct gtaatgcttt ataacatttt aaatgggata
    26641 tatcattaag tcccattgcc tttttcccaa tttcattaat atataaaagt tcatatgtat
    26701 ctaaagaaga aacatataca atttcatcca actcatctat taaatttatt acatccattt
    26761 atatatatct ccttttattc attttccaga ttgaattttt aaagctttta aaattttgct
    26821 atatatttgg caatgatatt atatttcttt atgttttaaa atagtacctt aatgaggttc
    26881 tattttttag taaatagaat tattattgtg tcaatcgtac aatagagttt tgtaatacct
    26941 aatttaatat atttataatt aattatctca ttatgtgttt ataattaatt ctcatataaa
    27001 tgacaaatct ccacctcaat taagtattcc aatcatatat gaagataata cttcattcat
    27061 ttaaaaatat aaaactatta tatattaaaa tttcttcaat aataaattat ctagattgtt
    27121 actttgatat attatataat atcacaaagg ctgatataaa aagacaaaaa gggcaatttt
    27181 tttatatcaa aaaaaaatgt taaattgata ttatccatat ataaattgat attatccata
    27241 tagatgctat atttaacaat tctacttact tcccttacac ttattagcat atagttatta
    27301 agagtttgtt gcaaaacaac acttagcaca ctttaaaaag tgtggtctaa taagtaatca
    27361 acgaagaaga cataataaag cataaaatat gatatacttt tccacgccat caaaactgag
    27421 gattttatta ttaatatatg ctaaaatatg cttaataaat taaattttaa tgggagaata
    27481 gttatgaaaa tatttagttt cttgttgttt gtgataggaa tatgtttatg tattgctgga
    27541 tttataggac attacccagt atttgttggt acaacattga gttttcttgc aattgcaatg
    27601 atagctgtaa gacaagtcaa aactaagaaa aaaatgaaat aggcaaatcc taactttaca
    27661 agttaatatt acacaagtaa ttagtctaaa attggatact ttttctatta cagaaataca
    27721 tcatccactt tgtattttct taaaaaaata aaatagctat gtaaattcaa gattagatag
    27781 attaactctc tatccatttc attgtaaaat atacatagct atttgtattc gatttaaaat
    27841 acttagattt tcttacataa caaataattt ctatctgatt attactcata ttcatttagt
    27901 aaccactcag caactaatca tttagtatct attcatccgc catacggtaa cctaccccaa
    27961 cctcagtcaa aatatattct ggctgagcag gattcttttc aattttcctt cttatacttg
    28021 ccataaaaac tctaagcgac tgattttcac tttcatagta atttccccaa actttatcta
    28081 ttataaactt atgggttaag actcttcctg aatacttaga catcaactca ataatcttat
    28141 attcgattgg agttaaatgt atttcttcac cattaattga cacaatatga ttttcataat
    28201 ctatctttag gtttttaact tcaaaagact ttggagcatc attatttata ttatcctgtt
    28261 gagctttatt tctaagagcc acacgtactc tagccaaaag ctctgttaca ctaaaaggtt
    28321 tagttaaata atcgtctgct cctccatcta aagcttccac cttatccctc tcatgctctc
    28381 tcgctgaaac aacaattatt ttattagtct ttgcacatgc cctaactcgt cctattacct
    28441 caatcccatc aatatctggt agtcctaaat ccaaaattat caaatctggg tcaagagaat
    28501 gtataagtga tatagctgtt cctccattat ctgtctctac acacctataa ttttgagttt
    28561 caagagatac ttttataaat ttacaaattg gcttatcatc ttctacaatt agaactaatg
    28621 gctttatttc cacttgtctt tcccctcctc atcatacata ggtatgctaa atctaaatgt
    28681 agctcctcca gaaggattat taaaggcgac aatttctcca ccatgagctt ctactataga
    28741 tttacatatc tccaatccaa gaccaatacc tcttctttca agatttctag acttattctt
    28801 agtataaaac ctattaaaaa tattcccgat atcttcattt ggtattcctt ttccattatc
    28861 tgcaacttca aatagtactt gatttgactc tttttttaca gttagttcta tcttagaatt
    28921 tttaggtgta tgccttatag cattatcaat tagatttact aacacttgtt ctattaataa
    28981 tacatccaca tgaacgatta ttatctcatc tggaatattt gtttttatgt ctctactatt
    29041 ggcaaacttt ttgactctta atatagattc agctattatt tcatcaacaa cttctggtcg
    29101 tttttcaata tccaattttc cttcatctat tctggtcata ctaagtatat tctcaacaga
    29161 atgagttagc caactcgtat cttcatatat atttttcaat aattctactc tagtttcttt
    29221 atctatcaca tcatcatttt caagtattgt tgaagatgaa cctaatatac ttgtaagtgg
    29281 agttcttaaa tcatgagaaa ttgacctaag caagtttcct cttaatctct ctctctctgc
    29341 ctcaagattt gcttttttat ttttctcaaa taaattttct ctatcaattg ccaacgcaac
    29401 ctgtgttgaa actgcttcta atagtatctt ttcattttct gtaataatat ctatcttaaa
    29461 acacgcaaca cctataacac caagaacatt tgattcttga ccttttatag ggaaataata
    29521 tgcactgctg tttttacaat attttgtccc aattccaact gggttacctg tcctaaaagc
    29581 ttcttttata gcttcttttt ctaatactga atggaatata ttctcacttc catcattgtt
    29641 acaaatataa atacttggct tacctagatt attattctca tctgcaatag tcactattac
    29701 agttctattt aatatattta ctaaattaga cccacaaaat tcaataattt gatttttatt
    29761 ttttgcttta agcaacgttt tgttattctc atagagcaat cttatcattt tttctctctt
    29821 atgagaaagt ctcacttctc tttttatcct agaagttaaa gtacttgtta taattgctgc
    29881 cattagcata atacaaaagg tcataggata atcttttcta taagctaaaa aagtatataa
    29941 tggatgcgta aagaaaaaat taaatgatag cactcctatt actgaagaaa gtattccaaa
    30001 aaaatatcca taggttatac ttgtagcaaa tagtacacct aatatgtata ctagtataat
    30061 attagattca ttaaaaccta ccttttcaaa aactactgat attccagtag caattgtcat
    30121 aaccaatata gtttttatga agtccttaat aattatcttt ttactgagat agccatcttc
    30181 atcataatca tactctttta agtcttcatg ttgtagtcgt tcctttttca tttactacaa
    30241 ttcctcctta ttgttactgt ttaaattggc tctattttat ataatacaat tttatcataa
    30301 taaattcaat caatacattt aattaatgta cttaaattac taaaaggtgc tgtcttaaaa
    30361 tgaaaataaa tctctatttc aaaacagcac ctatatattt aaattactaa tttagttttt
    30421 acatacttaa atcaatagtt ttattcaatt tcataaatta taatacttca attataaaac
    30481 atttctatcc aacaagcata aatataaagt gggcacatat acctgcacat aaaccaccta
    30541 tagtatgcga aagtatcgct ttaccagcca atggtcttgc atctaaagca tccatcatac
    30601 ctatgtgtgt acttaaatat ccactccaac acatacccat tgctgtgaat actgctatat
    30661 cattaggagt tatagcgcct gattttataa actctggtac taaagatatt gctgctccaa
    30721 cagctcctaa tgcagttaca gggaatgcta ttgcctctgg tgatgtgaat ccaaataatg
    30781 gttctattat gaagctaatc ttatcaccaa tagcaggtaa taattttata ccttcatatg
    30841 cagctcctgt gtaaacagct tgacctgtag cagggtctgt agatggtcca aaagttaata
    30901 acataactaa tgtacaaact actaaaactc ctggtattat agccataccc atttcaacac
    30961 ctaacttacc accttcaagt atagcatcca atgttctttg gaatacatta ccatctctta
    31021 tttctctaaa ctcttcaagt tttgcacctt tatcatttat ttgcttttca gtatcatttt
    31081 tagggtcata attataatac tttttagtaa aagtcaacat aattctaaca ctaataatac
    31141 tacctattat tgccgcaaca ttacctatta tagctggtag tacatattct ttaccttgag
    31201 ctatcataaa agttgttaca ataagtccca taccaaaggc tgttcctaaa ttacataaag
    31261 caggtacttg atacttctta aaatattgtg taaatgtttt gtctttagca aatggtataa
    31321 tagctggatt atcagataaa tatgttgcaa ctactcctgc tatactagca ccaggtaagc
    31381 cccatatagg tctcataaga cccttaaata tcttattaac taaagatatt actccaaact
    31441 ctgaaagcaa tgcactaagt gcacctgcaa gaactgccat agccattatt aaaaatactg
    31501 tgtctaataa aagcgcatgt gctgtactca ttattacttt aaacatcatt cctgcaccca
    31561 tgatgcttcc tacatatcca aatcctaccg ccaatagtac aataaatacg aaggtttcca
    31621 tacttactgc cttgactctt ctcttatccg acagcttttc catcttgaaa tcttccccct
    31681 tttaatttta aattaaggtt cctaacattg gtacaaattt tttggtacaa actgagttct
    31741 aaaacttaca ctcgtaatgc aagttgtcag ttttttgaaa taaaaaaaaa ttacgtttat
    31801 agaataagaa tatcctcttt aatttggata ctcttattct attttatgtt attatattat
    31861 catccttttg tttaaaagtc aattttttct atttttgttg tttaatttta tttatactct
    31921 ttttatattt ttcattttct tttatctttg taagtactcc atataagttg acttttctaa
    31981 atacagtagt tataaatacc aatcctaatg caattgaact tgcacacgat aatgtactca
    32041 ccccatattc tacagctttt atataattat tggtcaaaac agaatacata gtattatata
    32101 ttccataacc tggtactaat attattaaac agcaaacact taatgtagtt gctggagtca
    32161 tataaattct tgcacataac tcacaatata tcgcaaaaca aactgtagct ataaaaaaac
    32221 ataagttttc tgttactcct atatttaaaa gaaatttata tgaaaaccaa gctatacttc
    32281 cacctattcc tgctagtatt aagttttttc ctttcatatt aaatagcact ccaaagctta
    32341 aggcagtaaa aaaagctgct attacttcta taaacaaatg cacttatatc ccccctaact
    32401 tgaagtacaa tccaagtacc aagaacattc ctactgctat agatacacct acaaaaaata
    32461 cttctgctaa ttttgcaaga ccagaaatca actgtccatc taacaaatct cttaatgcat
    32521 tagtcaaagc aagcccagga actaagagca ttattgctcc tgctattaaa tggtctaacg
    32581 tctttatgaa tccgagcttt aaaattaaaa ttgaacaaga agctataata actgctccaa
    32641 ttgcatttac aaaaaagtca ttaagggaag atttacttaa atacataata acaaacttag
    32701 tcagaatccc aacagtaaat gcagctataa attcttccac atttcctcca aataatatcg
    32761 aaaaagttgc tgctgcaata cctgcaaaaa atattgttat taaatctgag taatagttat
    32821 cttcacttat ttcatctaaa attttctcac ataattcaat atctaaatta tttatactta
    32881 ttgctcttga taatgagtta acttcatgaa ccaagtttag gtctactctt cttgagctta
    32941 ttcttttaat tgctgaatgt aatttcccat ctacaaatac agatgccatt acagctgttg
    33001 gagttgcaaa tacatctacg tggtctattc caaaagattg acatattcta gctatcgttt
    33061 cttcaactct ataggtttct cctccacttt gcaacatagc tttacctgca tttgaggaaa
    33121 agtttaaaat tctatctata tccacaaaac atatctccca ttcttttata gtattattca
    33181 tattttaata caagatatta tttatttaaa ctattttaaa taattcatat ccaatattta
    33241 cattttatga aaaaacttgt tttttatgct tgtcaaaatc aaattttaag cttgtttaca
    33301 ccataaaatg gctgaattaa tatttgacaa acactttcaa ccatttatat aaccttctaa
    33361 attgtataac tttttactac aaataaaatt atatctcttt taattctttc tcttgagtat
    33421 ttagcttata gtaacttcat atttatatat gtacaatata aaacattatt tttatgatac
    33481 aaaatataat ttgtaaatgt atatatgtat taactgtgta tatataaatt attcttgacc
    33541 ttatcagttt tttcatatat cttcatctat accaaccata tattaataaa tgatattaca
    33601 tagacttaag tatattaaaa aacttaaatt tagttattta acaacataat actctaattt
    33661 aatctataaa aatccatact taatataatg caactcttat tttaacacca tctattacac
    33721 aaaacaacat attaaaaagt aaaatacaaa atatccacta taaaccttat tttaatactg
    33781 aatatatatt ataatatatt taatgtagct taaatatagt ttaaacataa agaaaggaaa
    33841 cggtatatgc taagaaaaga taaagttcta ttatctctac ataaattatg tgaaaatatg
    33901 actttaaaag accttcaatc agataaaaca ggattcacta caatagaaat tgctaaccat
    33961 tcatctcttg atagaagtaa taccagtaaa gaattaaata acctatacaa tgaaaaaaaa
    34021 gttctgaaaa tatctggtaa gccaatttta tttctacatg ctagtattat agaaaattta
    34081 attggccgta ctttgaacag tgatgaattt tctataaata attgtaatga gctacttaaa
    34141 tcaagtaaaa atgactcaga agatattttt tcaacattac ttggacatga ttctagtctt
    34201 aaactaccta tagaaaaagc taaatctgct atactctatc ctccaaaagg tcttaatacg
    34261 ttactaatag gacctactgg tgttggaaaa agtacatttg ctgaaacaat gtacaaatat
    34321 gctgtagaaa gtaaaatctt ttcttctgaa agcaaattcg tagtatttaa ctgtgctgaa
    34381 tatgcagaaa atgctaactt attattaagt aatttatttg gttatgtcaa aggttctttt
    34441 actggtgcta ataaggataa attcggcata gttgcacagg ctgatggagg catattattc
    34501 ttagatgaaa tacacagatt gccaccagaa ggtcaagaga tgctttttct tttgatggac
    34561 aaaggcatat acagacgatt aggagaatct gacattatgc acaaagctaa tgtctttatt
    34621 gtgtgtgcca caacagaaga tatacattct tctctgcttg ggactttttt aagaagaatc
    34681 cctgttacaa tcaacctacc tgctttacag gataggtctt taaaagaaag attatctctt
    34741 attaaatact tctttattat agaatcaaaa tacaccaatg caactataaa agttcacaaa
    34801 gatgtaatta aatcattact cctttatgat tgttttggta atataggtca gcttaaatct
    34861 gacatacaac ttatgagtgc aagagccttc ttaaattaca aaactggact taaggataat
    34921 atagaaatag atttatccct tgttcctgat tacatctata ttggtctttt aaaattgaat
    34981 gaaaatcgta gtaatctaaa taaattatca gaacttgatt atatgctttt ttatgaattt
    35041 aatggtaata acttagaagt tgaatataca aaagaactat ctaaatacaa tatagataca
    35101 tcaaacaatg gatttaaata ctctacagag attccttatc tggaaaatga tataaggagt
    35161 atgtttataa attacatgga aaagtactct acaaaattac tttcgatatc ttcagtaact
    35221 cattctgatt atacaagtaa tgagattttt aaagtaatca atccaaagat ttactatgct
    35281 gttgaacatt ctttaaaaga ggctgaaaaa atatcgagaa acaaatacac aaaacaaact
    35341 tatattgctc tttcaatgca tataagtgca cttatagaaa atataaatca agacacatat
    35401 aatcctaagt acaatttata taatgataaa attttcttag ataaagattt aaatatagct
    35461 aaaatagttt taagtataat tgaaaatgac ttacaaacat ctttacctaa agatgaagta
    35521 aaatttatat ccatgtttct aaatagcatg tatcttgaac caaacaatca atctgaaagt
    35581 ataggagtca taatacttgc tcatggaaat tcaacagcaa gcagtatgtg tgatgtagca
    35641 aattcattgc ttggtacaaa ccattgtaat gcaattgaca tgcctcttga tgtaaaagta
    35701 agtaccatac ttgataaaac tatagagttg gtaaaagaat gtgacgaagg taagggtgta
    35761 cttcttttaa cagatatggg ctctcttata gcttttggag aacttatttc agaaaaaaca
    35821 aaaatcaaaa ctcgctcaat tgaaatggta tctactccaa tagttttaga agcagtaaga
    35881 aaaagtacac taccagaaat gactttggat gaattagcta attccttaag ctctttaaat
    35941 ccatatattg gacgagcagc aatcgattca acagaaataa actatcctga aaagtcaaga
    36001 gagtatgtaa taataactac ttgtataaca ggatatggtt cagctatgaa agtagcagac
    36061 tttataaatt cttcacttaa aaatattagt aaatacaata ttaatttagt tcctcataat
    36121 atagaaagtt ttaaaatgta taagaataaa tttagtaata ctaaaattct ggcagttgtt
    36181 ggaagtgtag attttaatgt agccaacacc ccttttatac acatagagga actactaaat
    36241 ggatatggcc tagatatgct aaacaaaata atagaaggta cattcaatgc caatagtatt
    36301 acaaatataa aagaaacaaa tctatcatac aacagtttaa taataaactt tatgacccaa
    36361 aacttagagc ttttggactc tgttaaatta ttcaactatg tcaattcttc cttatttaca
    36421 ataatagaat taatagatga aaacttaaag agcaaattta agctaggata tatactacat
    36481 tgctctttta tgatagaaag atgttttaaa aatacaactt ttccatataa taacattact
    36541 gaattaatta gtaaaaatca tgaactatat agtttaatac gtgaagcctt taagccaaca
    36601 gaagcttatt ttaatatttt gataccagac gaagaaattg cttatataat agacatgatt
    36661 aatgagtatc taaataaata aaatttatag cacttatttt gtgcatatta attaatatat
    36721 gaaatggagg acgagatttt gaaaggaaaa ataaaacagt taacaatact tgcattaatt
    36781 tttatattta taactcctgt atttgcattt gcagatactc caccagtacc aaattcttca
    36841 agagcagcac tacttataga ccaggaaact aaaagaatat tatttgaaaa aaacattgat
    36901 gaaaaaatgc cattagcgag tttaagtaaa atgatgacct ttttattggc aatagaagca
    36961 gttgataaaa atcaagttaa agagactgat atggtgaaaa tagacaagtc tacagcttca
    37021 gtaggaggtt ctacttgtaa acttaaagat ggtgatgaaa tatctctagg agagcttatg
    37081 cagggtctaa tgctagtatc tggaaatgat gctgctatag ccatagctaa acatattggt
    37141 aaaactgaaa agaattttgt aaatatgatg aacaaaaaag cagaagaaat aggaatgatt
    37201 gatacgtatt attttaatcc aaatgggctt cctatatata ctgacccaga acataaagaa
    37261 cctcctattg aaaatatgtc aactgctcac gatatagtta cacttggaaa gtatatgtac
    37321 gaccattatg aaaatcaagt tacaagaata accactatgc aagtatataa tgatactaaa
    37381 aaggatttta cacattataa cacaaatcct ctgcttgttt cagtacctgg tgttgatgga
    37441 ataaagacag gatatacaga taatgctgga tattgccttg cattttctat gatggtacct
    37501 aaagatgcta aaaacgaaag aaatcataga ttgataggtg ttgtacttgg tgatggtaac
    37561 aagaaaaata gaatttcttc ttccgctact ttattgaaat atggtaaaga taatttccat
    37621 tctaaaaaga tagcacataa gggtgatatt atagagactc cttgtgttga tggtattgat
    37681 gattttaaga taacagttaa ggttgataaa gatttgtatg gtgttgtttc agataacgaa
    37741 aatatcaatc ctaaggtagt gtttaaaaat atgaattatc ctatccataa gggagatatt
    37801 gttggtgttg caaagtatta taatgactct ggtaaatttg ttggaagtgt tgatgtaaaa
    37861 agtgaaagta atataggatg tattcctttg aaggataaga ttaagattaa ggttgctaag
    37921 ataaataaaa aacttgagat taaaaattct gtttgtttta aagcatagta aagcatatta
    37981 ttaaaagggt atgttaaatt tataaagact ccactttgtg gagtcttttt gttttttaca
    38041 aaaaattaaa atagtggcaa caattgagga tgtgagggag agttgccact attttgtata
    38101 gggtattata ttatgttttt aagctagttt tactatcttc tatgtttata taataactct
    38161 tgtgtgtgaa tttaattgat aattaatatg aaaattatgt gaagttttga tttatttgta
    38221 atatattcta ctactattat aatttttcta ctggatatac taatcatttg tttaacatta
    38281 tctgagattg atttgcaaac ttttatataa ctaaattagt tatataactt atagattcca
    38341 ttaaataccc taataatcat atatgtacat acaaagtcat gcttatgcaa aatctgcagt
    38401 ttcaactaac ttattatata aaccatcttt atgtagaagt tcagcatcat ttccagattc
    38461 tattactcta cctttatcta atacatatat attatcagca ctcttaattg ttgaaagtct
    38521 atgagctatt ataataacta tcttatcttg tatgtactct ttcaagttgt tcaatatctc
    38581 tttttgtgaa atattatcta gagctgaagt tgcttcgtcc agaataagta cctttttatt
    38641 acttactaaa gctctagcta ttgatatacg ttgtttttga cctcctgata ttttgacacc
    38701 tttttctcct actacttcgt ccaatccctt atctagattt tttataaaat catctaaaca
    38761 agtaacttct aatatctcat ctaattcttt atcacttatt ttattattta atactatatt
    38821 attttttatt gtgtcatcaa atacaaattg atcttgagtt actatatcaa tattatttct
    38881 tagtgatttt aaattaatat cctttatatt aacaccatct attaatatat caccttcatt
    38941 tatatcccaa agtcggtata ttagatttgt tattgttgat ttgccacatc cacttccacc
    39001 aacaattcct gttacttccc ctttctcaaa ttgtaaattt atatcattta aaacaaggtt
    39061 taaatcctca ccatatctaa aagatacatt tttaaaatct attttcttaa tttcactgtt
    39121 atctattcta tatccattat tatcaacttt aatatctatc ttttcatcta ttactgaaaa
    39181 tactctattg atagacactt ttgattgtgc tattctagta ttcgccctta ctatagctat
    39241 acatggtcca attaacattc ctgtatattg ttgaaatgct attaactccc ccatcgtcat
    39301 cttattattt attattttat atcccccaat tccatatatt aatattgtta tcaatcctgt
    39361 tagtatttga gatattgcta tattactact cataatgatg ttcaaattca aatctttttt
    39421 tatcaaatct ctctctctct ttaaatactt attaaagaaa ttcttttttg aatttaatat
    39481 aacaatatcc ataatattag atacgtactc ttgaatcaaa tttgataaac tgcctgaatc
    39541 acttcttatt tcagaaattt tcttagatat aagttttgtc attttatttt gagaaaatgt
    39601 taatatcaac tgtaaaaata aaactactaa aaataaatca aactgcaaat taattaagaa
    39661 aattaacgat attatagctg taaacacatt tacaataata tcaaatataa tctctgctcc
    39721 aaagttttct atcataaata tatcactttc cataatggat aaaatattac ctgttttctt
    39781 acttgaataa tatctaccag aaagttttga tatatggtta agcaacttta cttttagatt
    39841 tatagtaact ttatttttta ttgaagtata taaatatgat aatataacat caaatgtagc
    39901 tgataatatc cttataaaaa tatatatcaa tattaaattt ataagcagaa aaatattttt
    39961 atttcctatt ccatcatcta ttatacatct aattagttga ggtattacaa tatttacgcc
    40021 agcaattata aaaaccatta taaatgatac tatcaactta gtcttattct tatatactat
    40081 tatatttagt attctaaata aattattatt aatagttttt ttcatctatt tttccatctt
    40141 ttatagttat aattctatca gctgtctttg caatattatc attatgagtt atcataacta
    40201 gtgtttgttt gtactcttta acacaccatt caagcatatt cataacttca tttgtagtct
    40261 tactatctaa gttgccagta ggttcatctg caaatattac tgacggtcta ttggctaaag
    40321 ctctagctat tgcaactctt tgttgttgac ctcctgatag ttcattcgga tatttcttta
    40381 tttgtttttc aatccccaac ttattaatta atctcataac atattcttta tcttcttttt
    40441 tcccatcaag caacacagga agtactatat tatcatatac atttataact ggtattaaat
    40501 tgtaactttg aaatatgaag ccaaattcct gtcttcttat ttcagacagc ttatcatcat
    40561 ttaatgtata taaatctaca tcatctaagt acacattccc taaagttggc ttgtctaagc
    40621 ctgcaacaca gtgaagtagt gtacttttac cagaaccact tgcacctaca atagctgtaa
    40681 atttatgtgg ctctatatct aaatcaatac catcaagagc tctaacttca ttctcatatt
    40741 ttccatatat tttttttaaa tcttttacct taagtatttt cataacgtat ctccattccc
    40801 atttaaaaaa catatatttt taaattaaat tttcgtaaat aagatctact gccatatcta
    40861 aattctctaa ttgatataag tatacttctt tgtagtcaat actaatatta aactctttat
    40921 ttaaaatagt taaaaaatta tatgcattat aatttccaat acatgtaaaa ttgttaaata
    40981 aagaatattc acttacaaat tcaaagtcta tttttatttt agaaaagttt ctatttatca
    41041 catttattat tttccttgct atatccaatc ttatcaaatt agatttataa cttggagtgt
    41101 tcaagttttc tatttttaaa tcttctttac ttttgctttt ttgaataagt atttcttcca
    41161 attcattaaa cttaatatat ggattgtttt ttaatatatt tgcaacaatg ccagttgcca
    41221 ctgcacaagc cttactattt ttaccaaaat gagttacttt atctttaaat ttaataaaat
    41281 tatcttttga atttgcatac atttgaatct tattttctgg ttcgtatata tattgattat
    41341 ttttatatat attttcatta cctactacac caataacact ttcaaatata gtaggaatac
    41401 tttctttatc ttcatattta ttatgttttg aacaaataat aaatctacct tgactattta
    41461 aaatattaca aaccttttct aattcttttt catacatact attaatagat gcagctgaaa
    41521 tgtttattat ctgtatatcc gacatagtca acttgctcag tgtactaaga agatttaaag
    41581 aacttgtttt tccagaatca ttaaatatat taataggata aatttgggta tttttactta
    41641 tatttaatat ggttttcgat acaaaagttc catgtccatt tatgtcattt atttccttcc
    41701 cccccaaatc tttcaattga aaatttgaat cataaacata atttccatta atatcatcat
    41761 catttacatc taatcctgtg tctaagactg ctattcttac tttagtcaat taataatcac
    41821 ctctaaaata aattaccttg aatataaaac taatccttac cataatatag gttccaagat
    41881 gtttttcatt tttttacaat ttgcatcaaa catttttttg ttatttttta aagtatatat
    41941 tttcgatgga caagttgtac aaaataaatt tactttacat tctttacaac tctcaatatt
    42001 tactggtttt aatttatcaa atatattaaa tatatccatt tctctattaa gaatcctctc
    42061 taatatgttt tcattaaatt ctaatatatt gaatatcttt aaatccttat actctaagtt
    42121 tggacacgga tatacatctc ctttatgatc tatacttatc tgattaacac ctgctttaca
    42181 catatttgaa cataaactac tttcatccac ataatcatct ttgcaaatgt aatcaatatc
    42241 aagtttatca ttaagatatt tgctatagtt ctcattacct ctaccaatat tcataaaatt
    42301 tcttattata ggcgttgtac ctaaatcttc atttaattta ttgaatttct ctatgtcttt
    42361 ctcattattc tttcctacca ccatagacaa acctacgttc tcgaattttt ttagttttat
    42421 aagtctaatc acatttaata ctttacagaa tactccttta cctcttactt cactacaact
    42481 taattcatca taaccatcta aactaatttc tattgcatat aaaccattaa ttatatcatc
    42541 aatctgtttt tctttaatta aagttgcatt tgtagacaga attattttac ctttaaattt
    42601 ttcttttata taatccaaca gctctaagaa atcatttctc atcaatggct ctccacctgt
    42661 aatggttaat atccttggat ttaatttaac tatattatct attacttttc ttacttgaga
    42721 tgtatctaaa taatcgttat tatctatttt agaatctaca cagcaataat cacaacttag
    42781 attacatcta ttagttggag aaaatgaaat tttgtttatt ctctctagtc taaattcact
    42841 tagaatagaa tcacttagaa gtcctatatg ctctaactta tctataactc gttcataata
    42901 ttttttatct tcattttctt ggaatacatc atacaaatta ccaagttgta atgcattatc
    42961 tactgaatac tttagaactt cataacattc tattggaatt ttaacccatc ttccatttac
    43021 tttattacta agaataactt gattattatt tattattttt tcacatatac aatctaaaaa
    43081 atatttgttt gagctattca tttattttat ttccttccta tatatttaaa ttagaaattt
    43141 cattaatttt cttttatacc acttactata ctaagtttat ttatcatttt attagaaaaa
    43201 taaactgcaa tgacacaaac aaaaacagat atagatccaa atattagaat ttcatatatt
    43261 ggaatttcaa atttaataga gttatttata ccatatacct gttgattaag tttgttagtt
    43321 tcagaaacta ttttataata attgaaacta gatataattc cagctacaat catacttaat
    43381 accccatata tcatattttc ttttattaac attcttttta catttttttt ggacatccct
    43441 attgctctaa atgtacatat ctcactcaac ctcacaatta tatttgatct aactataaaa
    43501 ataatgttta tagatgatat taataaaact ccaaatacac aaatcattgc taatttatat
    43561 gaggatttat tataatggtc tccaaaatga ttacgtacat atcttccctc tatatctgaa
    43621 aatccacttt tttctattat attatttatt tcttttatta cttttttatc tgtttctttt
    43681 tttatcttca caaaaacttt attataatca cttatccctg ttaattcttt taaatccttt
    43741 tcattaaata taatttgaat tccacctgat tgagattctc catcttgctc tgatatatag
    43801 ctatttttca ttattccagc gattcttact tttgtattta tatatttata ctctccatct
    43861 ttatatacag gaatttttat atctattaag tctcctattt taggtgattt tataatctga
    43921 gtattatttg acaatttaat tctagaataa aaattattta ccaataaaac atttttataa
    43981 tccctgtctg tataactata aacattttcg cctttatcta tatatttatc tatattattt
    44041 aatagctctt tattgtaacc tcgaattaaa actgtagact cattattatt atttatttca
    44101 gttcttttta gctcatctaa ataatcttct tctaagtcag catttcttag atatcctttt
    44161 aaataaatat tgggttcaac atctgttaca tcttcaatag cttttatttc atttaataaa
    44221 gaattatcat atttagaaaa tgtataattt gcatttattg gtgaatatcc caaataaata
    44281 tcaaaattgc catatgattt acttgttata ttagctgaat ctgactcttt tccatatatg
    44341 aattttgtag aagttagtct gcctataaat aaaaccccac atagtgatat cgtaattatt
    44401 attattattg atgtaacctt attcctaaat atatttttaa aagctatctc atttataatt
    44461 ccaacaactt ttttatgtga ttttaacaac aaaagcctag gaatataatt taacttatct
    44521 gtctttttta tagcatcaat tatagataaa tttccagctt tatatattgg tactacagag
    44581 gctaatataa ctgctataat tgacatgatg atagattcaa ttatagagtt tgtatttata
    44641 gttaattctg cacttttatc atatactatc atgagaccta agtaagaaaa aactatacct
    44701 ccaagtaaac caattactat acctacagat aaaactacaa tactctgaat aaaaaatacc
    44761 tgtctaatat ttctcttgct agctccaaca gctctaagta aaccaatttg cttggtcata
    44821 tctagtatta ttatgttaaa catattgtat attactaatg ttgcacataa taaagggagt
    44881 aagctttgct ttattgaata agttgttttt tttgaaatat ttttcatata catagacata
    44941 cttacttctg tatttggata aaattgatta cttgttaact tatattttct ccctagattc
    45001 actacttttt gagaatctaa atcttttgta ttcaatttta atgtacccat atgagttatt
    45061 aattcatatg gaacaatatc tttgccattg tttgaatatg taaaagctct taccttatat
    45121 ttatttaaat tttcatagta ttcatcagat ttacttaaaa taccaactat tttaaattgc
    45181 ttatctttac tataaataga attttcatta tttttattta tatgctcatt aacaatctga
    45241 aaatcaatag tttgatttaa tttgacatct aattccattt tgtctaaaac tttttgttct
    45301 attactaatt cattagaagt tctaggctct ctacctttaa ctaacttata tctagtagaa
    45361 tctaaaaaat ctttattgta agagcataaa tttagagatg ctccattatc tttacttata
    45421 atttctccaa atttaagtac atcattgaat tcttttatat cttcttcacc attaagttct
    45481 tttactatat cactatttat atcttcataa aaagcatgat aatctcccga gtttttgtat
    45541 gcatgattta tatctgattg tccttgagat tcattaataa cacttaatga aaaaactagc
    45601 ataacagcaa tccctatact aagtattaat gataaagttt ttcctttttg tctctttaaa
    45661 tatgacaccg caagtttaat atttatcata atcagaatcc tccttattca tatttacaag
    45721 aaaaactcta taacctaaaa tagtaggtta tagagcacta ttcattaaat actaactaac
    45781 tcgttgtgct agttaaattt aattattaaa aatactagag ttgagaaaat cacatttcat
    45841 ttgtaaaaaa ctacatctag tactttcaac atatttaata gactgattag tattttttaa
    45901 taagctactg ttccttttgg agttgatcct gcacaatcca ccatacagtc tatttgtgaa
    45961 attattccat gcttatcata ataccattta catggatctg cttgcacctc aacatcttga
    46021 agttctattt tttcttcgat tttttttata tgtatcataa tacatatccc cctttacttt
    46081 tgttttatat ttattataac tagttaaact agattataaa ctacatagtt tttttgttgt
    46141 ttccacataa actctttcta atccacaata aattggtact gcactttgga atttacctgt
    46201 taccttttta ttgataagtt tacatctggt tgacatacaa taatcaagtc tagtacatcc
    46261 atcacactct tcattcttag atatataaat ttttataagg ttcttaattt ttttatcatc
    46321 taatccatca tatatatttc ctagtaaaat atctttatct cctacacata ctgtacatgg
    46381 atatacatct cctctagtat ctattgcata actatttatc cctccaaaac aatctccttt
    46441 tttcttattt ataaattgtt tatctaaaat agatatatct atatcaggat aatccttttt
    46501 aatattcata attttactaa tttgttcatt taatatttta atatgagaat tatcccaatt
    46561 tttatccata aaatctgaaa ttggtgcgat atttttaaac ccttgttttg ctatatcata
    46621 tacactctca taaagatact taacagtatt tgagttatat gtcattcttg ccctaacata
    46681 tataccttta tctataagtc tttttccatt ttccattact ttttcataag tacctactcc
    46741 gttagcatct attctattta tatcatgtat attctttttt ccatcaatac ttatcgatat
    46801 gttttttaca ttctttgcta taaactctat tatttcatca tttataatag ttccatttgt
    46861 agttatatca aataatatct ttttgtcact caatctatct actaaatccc tatgtatata
    46921 tttaatcaaa tcaaaattta taaatggttc tcctccatgt aaaacaattg ttgtataatc
    46981 actattactt tctaattctt tattacaaat aaaatctatt gttttatcag cagtttcata
    47041 actcatattt tctttttttt tatcattacc ttcataacaa tatgtacatc tcaaattgca
    47101 gtcttcagtt acaaatatag taaatttcaa ttaacttttt catctcccca tacagctgta
    47161 tttaaattgt gtttcatcat actacaccat ctatccaatt ccaattcatt atccttaact
    47221 gaatctaata tcgctgggca atgccaacaa aaaatattta catcacaatc tttacatttt
    47281 tcaaagttat atggataaat actttctaat ttaatcaaag actttagatc tcttgtttta
    47341 ttttctttta taacttttac aaattcattg tcaaatatat ttcccatttt atagtcatcc
    47401 tttatcagtg aaggacaagg atatacatct ccatcataat ttataaatat ttgagagttt
    47461 cctgcattac atgcacaaca tcccattttt ttattttttt tatctttaca catttttaat
    47521 tcattatcta aaatatacgg aattgtaatt ggaagaactg tatcttcaat taaatagctt
    47581 tctttatttt ctaggcctct tcctgttgga ataaaatatc tttcaacaaa ttctgttcca
    47641 agctttttat ttaaatcttt aaattgttta tttaaatgag aatttttttg tccaaatacc
    47701 atagacagct ttatattact gaatccattg tcttttagca gattaacaga gcttattact
    47761 ttattaaata caccttttcc tcgtgtttca ctacaagtat tttcatctac tccatcaata
    47821 ctaatatcta ttttttcaaa attagttata ataaaatcaa cattatgttc atctattaaa
    47881 gttccatttg tggataatat taatttggta tcaggtaatt tttgttttat atatttaatt
    47941 atttcaaaaa aatcttctct tatcaatggt tctccaccag ttataattat atgaggagta
    48001 tttaaaactg atattatatc tacgatattt tttaaatcat atgtactaag taaatctttc
    48061 ttattagaag aagattcaac acaacaatgt ttacaaaata aattgcatct atttgtcaaa
    48121 caaaaataaa ttgcaacacc attgcttaac atatcaaagt ttaaattgtt acttttaaaa
    48181 atttgatttt tgttcataat atc
//
LOCUS       DAYAOO010000026        46248 bp    DNA     linear   BCT 12-OCT-2024
DEFINITION  TPA_asm: Clostridioides difficile isolate ST8-SSI-h139-18
            SAMN40601845-rid21577343.denovo.026, whole genome shotgun sequence.
ACCESSION   DAYAOO010000026 DAYAOO010000000
VERSION     DAYAOO010000026.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN40601845
            Sequence Read Archive: SRR28438827
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 46248)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 46248)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-MAY-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-MAY-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002157583.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002157583.1
            Genome Coverage       :: 163x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/11/2024 16:19:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 4,038
            CDSs (total)                      :: 3,963
            Genes (coding)                    :: 3,930
            CDSs (with protein)               :: 3,930
            Genes (RNA)                       :: 75
            rRNAs                             :: 6, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 60
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 33
            CDSs (without protein)            :: 33
            Pseudo Genes (ambiguous residues) :: 0 of 33
            Pseudo Genes (frameshifted)       :: 7 of 33
            Pseudo Genes (incomplete)         :: 25 of 33
            Pseudo Genes (internal stop)      :: 11 of 33
            Pseudo Genes (multiple problems)  :: 8 of 33
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..46248
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN40601845-rid21577343.denovo.026"
                     /isolate="ST8-SSI-h139-18"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Denmark"
                     /collection_date="2018"
                     /collected_by="Statens Serum Institute"
     gene            465..587
                     /locus_tag="ACGI5H_001574"
     CDS             465..587
                     /locus_tag="ACGI5H_001574"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9697284.1"
                     /translation="MMDLEKEKHEIIEIIKKLNIDKDKRNLLMIKNYILGLLKK"
     gene            complement(602..988)
                     /locus_tag="ACGI5H_001575"
     CDS             complement(602..988)
                     /locus_tag="ACGI5H_001575"
                     /inference="COORDINATES: protein motif:HMM:NF024252.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HFG9697285.1"
                     /translation="MIDEMKPENKRIRELRLNLNLSQEEFANKLNLKRNTISLIENGK
                     RNASERTLNDICKTWSISEEWLKHGVGEMFFIKELDEQFAHLVGELSKMENEVEREII
                     TKMFKLNKKYLTVFDKMIDSLLEIEE"
     gene            1136..1279
                     /locus_tag="ACGI5H_001576"
     CDS             1136..1279
                     /locus_tag="ACGI5H_001576"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9697286.1"
                     /translation="MTDINKIREEIYRKLELLGPAKLKLALTKVDILKEIQDIEDENN
                     IQN"
     gene            1284..1508
                     /locus_tag="ACGI5H_001577"
     CDS             1284..1508
                     /locus_tag="ACGI5H_001577"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894551.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9697287.1"
                     /translation="MKRLKISDFNKNQIGSAVQLQDIRFDTKADCIITKVEKNEILVM
                     YYEKETEEIAYKTLTKEDLILDDYKLKLLS"
     gene            1527..2267
                     /locus_tag="ACGI5H_001578"
     CDS             1527..2267
                     /locus_tag="ACGI5H_001578"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009899661.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HFG9697288.1"
                     /translation="MITLDLLKDARKKEWFWLENDLIDREDLSIYEKMIYIVLARYSN
                     EESSCFPSYKTISEKAGCSIRQVSNILNELENKELIIRENRNHEGKKEKNSNLYFLIS
                     SKAKVQNEVPNVRHEVPNPMAPGALHVRHEVPSKKTYNKKTYIKSNTTTQKESKTDYL
                     DLSFLDLDIEKVKLTKDEYDKLISKFGKKYIHDKIVSLENYIINGKGSRYKSHYRALL
                     TWGNGDASKGIVPEVTKTKNPLSGFKEL"
     gene            2295..2480
                     /locus_tag="ACGI5H_001579"
     CDS             2295..2480
                     /locus_tag="ACGI5H_001579"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425623.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9697289.1"
                     /translation="MNEKEETVYLNSSNVKLFLGVRDIKEFEELIENVNERICQLQES
                     INKLAQFNIEFDIKSDI"
     gene            2506..2724
                     /locus_tag="ACGI5H_001580"
     CDS             2506..2724
                     /locus_tag="ACGI5H_001580"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009899664.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9697290.1"
                     /translation="MKDEKLELTEKDLHCIARHLQNEVMEMVFRGNIEAPTSCEVCDY
                     LQECKDYFTHIDTFIKLSEMTGVDIFTK"
     gene            complement(2743..2949)
                     /locus_tag="ACGI5H_001581"
     CDS             complement(2743..2949)
                     /locus_tag="ACGI5H_001581"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009899668.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9697291.1"
                     /translation="MCKIKTLREKCSLIDDKVEFSGEYKTFPGFTGSKLLECECNKNY
                     ICKIQIMTANSNCPLFKKARQLQY"
     gene            3118..3378
                     /locus_tag="ACGI5H_001582"
     CDS             3118..3378
                     /locus_tag="ACGI5H_001582"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894547.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9697292.1"
                     /translation="MKEEKLELTEKELHCIARHLQNEVMEMVFRGNIEAPTSCEVCDY
                     LQECEGDFTCMYHSFTKLSKITGVKVTAFKYCFPDENPKATI"
     gene            complement(3371..3559)
                     /locus_tag="ACGI5H_001583"
     CDS             complement(3371..3559)
                     /locus_tag="ACGI5H_001583"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425627.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9697293.1"
                     /translation="MSQYRVISKECPVINETISLTCEYSAPPGTFGSKLMSTRCDGSH
                     ICDSSSNEECPILKKLLR"
     gene            3697..4014
                     /locus_tag="ACGI5H_001584"
     CDS             3697..4014
                     /locus_tag="ACGI5H_001584"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425628.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9697294.1"
                     /translation="MERKKHEFTDQDIQRLIEGLRTDPKIREMIFKSKGCETRTSTRS
                     KCEQFVEEKLAYRSYGFETPKYYAKLIADIIDILVYKNVPRDRICGVLYDVERVIPLV
                     VTF"
     gene            4036..5367
                     /locus_tag="ACGI5H_001585"
     CDS             4036..5367
                     /locus_tag="ACGI5H_001585"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009899669.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003678 - DNA helicase activity [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006260 - DNA replication [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DnaB-like helicase N-terminal domain-containing
                     protein"
                     /protein_id="HFG9697295.1"
                     /translation="MNYSLEAEQNILGSFLINDSIGYKIRELKENDFYFESHKIILSC
                     MKKIIDSNKPLDLLLLKNELEKIDRLVDIGGVSYITSLTTIVITTSNIDHYIKIIKEK
                     LLKRQISELANELINNSNSDTSIDELIIDINDLKALVTTSSSVNDNYIDASKIKREKG
                     VHKSIDTGFNKLNNMLDGFRYGTLTILTGKPASGKSTIVNQFIAQAITNGEKAFLYSG
                     ELPSFMSMDWFRKTVANDYHIKEYKSVYGGTYTDIPDYAVELISDWIEDKFFLYDEDA
                     ISDEVNLLNTIEHLYLKKGVRFFVLDNLMTIKTGNKADKYERQEQIVSNLKNLAKKYN
                     LVIVLVAHPRKNMGDMKPTMYDVSGASEIVNYADYILSTYRVVDEEEETDDTYLLILK
                     NRITGKQNISFKMNFSERRKRLYTTSEELNRDYKYDVNKQYVQVEIPEDVF"
     gene            5742..6128
                     /locus_tag="ACGI5H_001586"
     CDS             5742..6128
                     /locus_tag="ACGI5H_001586"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003431627.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9697296.1"
                     /translation="MIALEKFAGGVLKEKFNTELQKVLDNIADPNTDFKKTRKISLEI
                     VFKANEDRDLAEVDIKSKATIVEAKATTTKVLIGKDLETGRVEASEFKNQVAGQLVMD
                     IPDSEETNETEENSAGVIDFRNASSK"
     gene            6181..6885
                     /locus_tag="ACGI5H_001587"
     CDS             6181..6885
                     /locus_tag="ACGI5H_001587"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894543.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9697297.1"
                     /translation="MIRNAMEYLVKLGKRETVCVDGFKYTTDALEIIKEPKANELEIT
                     TLSGLVDYIKSGIDHKADELLLIQVLTPRKVLLKSPLRKNRDRETYIECVALLPEKRF
                     DRPLDLDSFNIMLQSAFIKNNDRDTLLKIAGNIQESTVKNVGDDGVSQSVTIKTGVAS
                     VSEAIVPNRVKLIPYRTFQEIEQPESEFIFRMSSGPAAGLYEADGGAWKNQAMLNIKA
                     YLQEELKDFKNVNIIA"
     gene            6942..7124
                     /locus_tag="ACGI5H_001588"
     CDS             6942..7124
                     /locus_tag="ACGI5H_001588"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425632.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9697298.1"
                     /translation="MKMISHMNILERAEFTDKIANAIMSANKEIERGCAFNEAVEIVK
                     QMEYRENKYNEGDIAI"
     gene            7121..7498
                     /locus_tag="ACGI5H_001589"
     CDS             7121..7498
                     /locus_tag="ACGI5H_001589"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425633.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded DNA-binding protein"
                     /protein_id="HFG9697299.1"
                     /translation="MNNVVLVGRLARDPELRYIPEYGTPVATFALAVDRGYTKKDGTR
                     EVDFIPIEVMGGSAEFCANYLAKGRMVSIQGQIRIEKYEKDGEKKTFTKVRTKIVNAL
                     DRKPKDEEKEISFQVLDDEDIPF"
     gene            7515..8063
                     /locus_tag="ACGI5H_001590"
     CDS             7515..8063
                     /locus_tag="ACGI5H_001590"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894542.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003899 - DNA-directed 5'-3' RNA
                     polymerase activity [Evidence IEA];
                     GO_function: GO:0016987 - sigma factor activity [Evidence
                     IEA];
                     GO_process: GO:0006352 - DNA-templated transcription
                     initiation [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-70 family RNA polymerase sigma factor"
                     /protein_id="HFG9697300.1"
                     /translation="MRSLEERNKLVEENINFVWFIIRRYFKVFISKYPYLQDDTFSEG
                     CIGLCKAADYFDSKKGIEFTTFAAVCIKGQIFKFISRYVKKHYRADIDSFEKCIYKNT
                     HGEEIRIEDRLAGNENVDIENVHVIRSCIKRSKIEDIQKITYLREKGYTQKEIGKILR
                     TNQMTICRKLGKLKSEINILGK"
     gene            8093..8251
                     /locus_tag="ACGI5H_001591"
     CDS             8093..8251
                     /locus_tag="ACGI5H_001591"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425636.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9697301.1"
                     /translation="MKTKIIGGRENQCPLCNGSVFKIETSIGIVWQCKDCGCMYQDMN
                     CKENKRRH"
     gene            8254..8580
                     /locus_tag="ACGI5H_001592"
     CDS             8254..8580
                     /locus_tag="ACGI5H_001592"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003431631.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9697302.1"
                     /translation="MACVIKCDFCGETIAEILNIKVFRIDDEGNIMSIGKDVCDKCYD
                     RLFRSNLNKKMTNYEKIKNMSKIEMAEFLANGGSGCTSCAYDFQECLGGCLEGRKKWL
                     ESEAMK"
     gene            8580..9116
                     /locus_tag="ACGI5H_001593"
     CDS             8580..9116
                     /locus_tag="ACGI5H_001593"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425640.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LemA family protein"
                     /protein_id="HFG9697303.1"
                     /translation="MKKTLIIVGVVISILIMFACLFLVTKNKAIDLEEQVQSATASVE
                     VQEKRRIDLIKNIVDCVKDYAKYENRTLKEVTDMRVSANDESIKEAKLNIQAVAEKYP
                     DLKANENYKQLMSELSITENMIAQHRENYNMQVRNYNKYIRKFPANLILNSMGYEKIE
                     SKYTEYKAKEDAPQNLFD"
     gene            9128..9934
                     /locus_tag="ACGI5H_001594"
     CDS             9128..9934
                     /locus_tag="ACGI5H_001594"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425642.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9697304.1"
                     /translation="MKFKTFEITKREFLVSIIIACMMIVLGFFIDDKVQSKFLEDNER
                     YYKATKINNDKDLFDYAMETSAGDSLISGRFKSVDSVSIEELKGDYWFIERTEEKYTM
                     HTRVVTTKDSKGHSHKYTETYWTWDYHDSIEKKCNKFNFMGKEFDAKVITNLSKERLA
                     LKKDIFKNNNLKIKGNYAYINNKRRYYYEVIPKEFNGTMYANLKNNTIANPADKNIKV
                     FKGESIQNVLENNNFNTGFFKVVFWIIWILITTIIIYVFYYLKNDWLEDK"
     gene            9959..10219
                     /locus_tag="ACGI5H_001595"
     CDS             9959..10219
                     /locus_tag="ACGI5H_001595"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425644.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9697305.1"
                     /translation="MKCKVYHAIKNIKDANELIDRFETENIFFELNDIDNENVLNGEM
                     NLTDIEDIASLQFILDGDLFIFSSCDEMIFMNKYTQKELGLQ"
     gene            10243..10728
                     /locus_tag="ACGI5H_001596"
     CDS             10243..10728
                     /locus_tag="ACGI5H_001596"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425645.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9697306.1"
                     /translation="MDLKLISSIPNWKVEDQLAKIDEEVTEFKNAIDTGITKDIIAEG
                     LDVCQTILTMFQVLEIENYITEGVETHNKKLNGRGWDLKEIGDDILNLIKNSMINELI
                     NMNKKLKCLDEKEFNAKIQFLDVDKLWNLCMPLVNLSTIKGVNESIDEMKMGEFLKNI
                     N"
     gene            10748..11005
                     /locus_tag="ACGI5H_001597"
     CDS             10748..11005
                     /locus_tag="ACGI5H_001597"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425646.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9697307.1"
                     /translation="MLIEVTENNRELKVGDIVEINGGNKLYMILSLKETIGGYVIINM
                     QNGYGSFGAYKSLSQLELDLKVRGYKLYSSDDYKLQLVPRE"
     gene            11114..11557
                     /locus_tag="ACGI5H_001598"
     CDS             11114..11557
                     /locus_tag="ACGI5H_001598"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003431634.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA polymerase subunit sigma"
                     /protein_id="HFG9697308.1"
                     /translation="MQSSKKDNLFSSAEGKLYDYKKIKAEIEKIDIDMQMIKNDYRGC
                     SGVEIKEKTGKTYDIKSVIEIETEEKEKKIALKEKEKRHKELIIEKIDNAMKILSEEE
                     KKIVQYKYFSSSRTSWEYVGRMIGFSASKCKQMRFDIIDKIKGLL"
     gene            11745..12245
                     /locus_tag="ACGI5H_001599"
     CDS             11745..12245
                     /locus_tag="ACGI5H_001599"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003431635.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9697309.1"
                     /translation="MLKIKRDITEEISSAAYVPDNLKYYDNVMKETPGMYGRECSLDF
                     IKKKQEKLLKLKKKVKKNYDSNINKIDSYLKILEKSIIDESDHVELVVFKLYLQLENV
                     VKVTETVNDLGFRIKTNTYARERKYSTNDITSIITDPFTDVVEDLKILVQERQRKNYY
                     GNKECF"
     gene            12249..12893
                     /locus_tag="ACGI5H_001600"
     CDS             12249..12893
                     /locus_tag="ACGI5H_001600"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003431636.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA];
                     GO_process: GO:0015074 - DNA integration [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HFG9697310.1"
                     /translation="MEAHSGQKVNPIKDIEDVFRLLNFLEEWNERNYLLALFGMCTGL
                     RVGDILALKVADVTDLKLDKKGNKIRVSKDWIRVIEEKRDYNREVFLSDVIKSAIENY
                     TQDKPGEEFLFKSGKRKKFNRPIQTRQAGRIIKGAAKKVGIKENVATHSLRKTFARHI
                     YDEEENKTYALELIRKILGHKTIEMTRRYIGIDKDEEVKAITKFTNKLKKRKRN"
     gene            13114..13566
                     /locus_tag="ACGI5H_001601"
     CDS             13114..13566
                     /locus_tag="ACGI5H_001601"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894533.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0043565 - sequence-specific DNA binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HFG9697311.1"
                     /translation="MNEVEIIDSSYEKGKELTEDQCNMVTLLITGATVTETARIIGVN
                     RKTIYNWMNKEHVRKEMDRRKQELTNQGNLMILKDLDSYINNIKELASDKSDKRVMLA
                     ANQYLINRIYGTPTSTVIQAEDNSVGMGMDATEIEAAIAKIRIRTSKK"
     gene            14121..15860
                     /locus_tag="ACGI5H_001602"
     CDS             14121..15860
                     /locus_tag="ACGI5H_001602"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9697312.1"
                     /translation="MDNLERNIQLIFSYLAKTFIRNGASIKDAEKEANEIIKANSNNL
                     WGVNGLAYQLGKINLEFFCMYFMQDTYLPKEDNAAAPIAKVHHELWEDIQESIIGDGS
                     QQLGRIYPRGTGKSAFGDLATTVWSHCYKHKTYTLICSDIGSTAEKFVKDIKNALLEN
                     EYIKKAFGVLLNDNDRKYICNSTQLELTNKTFIEAISSSSPMRGRKYNNNRPDLIILD
                     DYQSEENVRTEDAREKKFKRFSDDVKYAAQKPVIRNGKTIKRGTTFIALGTLQHKECF
                     YSRLKNLPTWKFKCEKGVLVDNVDELFNSGLWLKFKEILFDFKNTNHLEDAKEFYWEN
                     EKEMKFPILWPSFWDCLDMALSYYENPTSFKQEVQNDVNSIGEKWFKTVRTETREEIE
                     SHTFKKTMLLCDPASAGGSKHDYSAFLVGSESENGLLYGRLAELAKINARTDFDKYID
                     HMIYLLKVYSDITHIYIEKNTFNGADANQLEFKIKNDNVLSYRDIEIINEQQKKNKDD
                     KISTLIPVLSKGQMIFAEEDKEFIQQILDFTGQKYSLHDDAPDISSEFINRINNIKVS
                     ETVNIFDRKLLGF"
     gene            15876..16064
                     /locus_tag="ACGI5H_001603"
     CDS             15876..16064
                     /locus_tag="ACGI5H_001603"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894558.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9697313.1"
                     /translation="MANRSKFEEVQKTLTKKGKKFNVGIGKDEKGYFAYTHRARSKSY
                     ISKQDIPIKVLKFIESTG"
     gene            16077..17354
                     /locus_tag="ACGI5H_001604"
     CDS             16077..17354
                     /locus_tag="ACGI5H_001604"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009899679.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0019028 - viral capsid [Evidence IEA];
                     GO_process: GO:0099001 - symbiont genome ejection through
                     host cell envelope, long flexible tail mechanism [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phage portal protein"
                     /protein_id="HFG9697314.1"
                     /translation="MELDLDLIKDIYDDWNSNKSEYDTMYKYYKGETDAISNYKMVTK
                     RSNNKINTNFLKKFINEEVAYSLANKITYTSRSGDEKIINDLEYYTCHWSKKHDSDLL
                     RYALLFGLCYELYYVKDDEIQVKIIKPTDGCHYENENGEIVCFIREFTKGFEDDTYVD
                     VYDKEYIYHFDSNFKEVESPTVNNIFDGNVPISICKRSEELGKNTIFNDIKGLQDAYE
                     TNLSDISNEISDFRNAYLTFSGCNIKEDDLPRMKELGILQVNGDGKIEWLIKDMNDTF
                     VQNTLSSIKENMYEITSHINHNEKMQSNTSSLAVIARLISTEWICSQNNDSIADTLFN
                     RYKLLCIWLNKKYGFDYDYKDIKAKFTPKIPRDDLVVANILSQLGDKLSTETGLSQLS
                     FIDNPHAEIEKAKKEQEIVSEGEILLDESKDYN"
     gene            17332..18093
                     /locus_tag="ACGI5H_001605"
     CDS             17332..18093
                     /locus_tag="ACGI5H_001605"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425655.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0044423 - virion component [Evidence
                     IEA];
                     GO_process: GO:0016032 - viral process [Evidence IEA];
                     GO_process: GO:0019068 - virion assembly [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="minor capsid protein"
                     /protein_id="HFG9697315.1"
                     /translation="MNQKIITKLTEDIYKSAENRTKPFYKYQRENRDKLLLEIAKILL
                     THDIINEYLNINNKDKKNLRSKLNKIINEYSNSYDEEVKDIETILSDSSKNKYSNLII
                     LLGVILKIKDVSNINNKVINKIVNNKVDGKHWSDRLWKNKKGIEESLKKEIKSFLNGK
                     TSVNKIEKAIRDKYSTGAGQTSRLIENEVARCQSEVNEYFFKVQGIIKVMYCADLDSR
                     TCSDCSMHNGVIFYVNEDRPSLPRHCHCRCQYIPV"
     gene            18152..18478
                     /locus_tag="ACGI5H_001606"
     CDS             18152..18478
                     /locus_tag="ACGI5H_001606"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425657.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9697316.1"
                     /translation="MKVEILGTEYLVIEKLESEDVLLKERAGYCDHSVKEIVIEKINS
                     EEGSLKDLSVYKNEVARHEIIHAFLSESGLKSCSSWATNEEMIDFFAIQFPKIVKVMD
                     KIECLN"
     gene            18504..19106
                     /locus_tag="ACGI5H_001607"
     CDS             18504..19106
                     /locus_tag="ACGI5H_001607"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425659.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4355 domain-containing protein"
                     /protein_id="HFG9697317.1"
                     /translation="MLKKEVLELLKEIEDDAEIDSLLQSTDLFKSASDKKLTIEEFRE
                     LINNDANFKAIIDNEKNKYHSEALENFKKKDMQTLISAEVLKRTGANETEEQKAIREL
                     RESLDKLKKEKQYAEKVSKYKDILVEKKIPTNLIEYLLSDDDDKTNANIEIFENSMKQ
                     YVQSKVDERIKDGSYVPPGKDSAGSLSEIRKQIKQGLNSL"
     gene            19135..20058
                     /locus_tag="ACGI5H_001608"
     CDS             19135..20058
                     /locus_tag="ACGI5H_001608"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894560.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9697318.1"
                     /translation="MANVLQYVTLFQQELDMQVTVGSTTGWMEKNAGQVIYNGGREVK
                     VPKVTMDGLGDYDRSKGYTQGAVTLEYETMKMEMDRGRTFMLDSMDVNESNFVINASS
                     VMGLFQKQHVIPEIDAYRYSKIFSETAKVDERVKYSYEATVTTILSELKNQLASIQDL
                     SGDIPLIISMSSIIASILEQSSQLDDIEFGDGDIKRIVKSIDNVPIIKVPSKRMKTEY
                     VFRDGKTSGQTEGGFTEGAKALDINWLITPASAPIAVSKTDKPRIFTPDQNQTADAYQ
                     IDYRKYHDLWILDEYLKLCRASVRQAKAAQE"
     gene            20072..20344
                     /locus_tag="ACGI5H_001609"
     CDS             20072..20344
                     /locus_tag="ACGI5H_001609"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894561.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0006353 - DNA-templated transcription
                     termination [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Rho termination factor N-terminal
                     domain-containing protein"
                     /protein_id="HFG9697319.1"
                     /translation="MFALIKNNIIKVVEDENSRDKLISKGFKIYSEEVTKENIEKKEE
                     KVKSTSNDLFNLSKPELMEIAKGKNIKGYSTKTKEELIQLLDEYNA"
     gene            20337..20708
                     /locus_tag="ACGI5H_001610"
     CDS             20337..20708
                     /locus_tag="ACGI5H_001610"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage head-tail connector protein"
                     /protein_id="HFG9697320.1"
                     /translation="MLDNVKLVLGIENDRYDKLIILYINKISEMVLEYCSRQELSTAL
                     EGFVEEKVISILSSRFEELKKNSGLDNLEKSLKAITRGDTKIEYNALTLQTAENSISS
                     SSFLTDTDKKFLSPFCIVSMY"
     gene            20720..21067
                     /locus_tag="ACGI5H_001611"
     CDS             20720..21067
                     /locus_tag="ACGI5H_001611"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9697321.1"
                     /translation="MTEADILEMTYLDKMTIIRKLKGWNEETCSNDFSNVVIAENIPC
                     AISRKEEAIVNGDIGSIVVNRKLFCRPEVDIKIGDTINTTYNHGEEAVFKVSKANIYP
                     SHMEIPITELERI"
     gene            21067..21423
                     /locus_tag="ACGI5H_001612"
     CDS             21067..21423
                     /locus_tag="ACGI5H_001612"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425669.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HK97 gp10 family phage protein"
                     /protein_id="HFG9697322.1"
                     /translation="MGIDNLGVFEALALDLGLNASNFNRKIKKFTKETGQELAENIRD
                     ETPVKTEKLKKGWEEKQPEYDTYIVKNEVDYATLVNNGHSTKNGGIVPGSFMVEKGIE
                     RTKENMTSAKANLFDW"
     gene            21432..21881
                     /locus_tag="ACGI5H_001613"
     CDS             21432..21881
                     /locus_tag="ACGI5H_001613"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009899640.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF6838 family protein"
                     /protein_id="HFG9697323.1"
                     /translation="MLTNRDIIIAVNKRIENEFRYIDIFINEDNIQGFEEACFFVQLL
                     PVSNNIANKVLDTKKIFIDIEYYQKARKNKLNLYDIQSRLEKIFNRNIRVKDRSLIIE
                     NISPSIAKDPVGYKLTFLMTVSYFEEVYFENETFEIMESVDLEIGSD"
     gene            21882..22937
                     /locus_tag="ACGI5H_001614"
     CDS             21882..22937
                     /locus_tag="ACGI5H_001614"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425673.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail sheath subtilisin-like
                     domain-containing protein"
                     /protein_id="HFG9697324.1"
                     /translation="MGLPEINISFIQAGKTFVKRSGGIVALILKDTKNIGLVEIKEIE
                     DIPENYSAANLDYIKMAMKGNVYPPNKVLVYTLDTDESIDDALDFLETCEFNYLCMPD
                     ETEQDLPKIKTWIKKMREDNKIKVKAITASNSADYEGIINFTATDIEVEGKKYTSNEF
                     LPRIAGFIAGTPSTQSVTYAEIPEVTNIPKLTRAEANTRINNGELILIKESGAIVIAR
                     GVTSFTTITDSKGDIFKKIKLVDTLDQIHNDIKKIIVKNYIGKTQNTYDNKCLLIVAI
                     QLYLQELEKDGLIDEGSTVEINLDAQRAWLKKQNIDISNMEEQQIKEYNTDTLVFLKA
                     RIKLIDAMEDVYLDISM"
     gene            22953..23393
                     /locus_tag="ACGI5H_001615"
     CDS             22953..23393
                     /locus_tag="ACGI5H_001615"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail tube protein"
                     /protein_id="HFG9697325.1"
                     /translation="MKAKIDAKRIISGTFGECWLDNKQLTSTKGMEAKVDIDKEEIKL
                     CGQIMTTYKMIGATGKGSITLYKISTLFGEYVEKMLNEGKEFKVTIISKLQDPDSYGS
                     ERIALYGCMFDDLTLADWEAAKVGEIEVPFTFEGFEYLDKIKEK"
     gene            23408..23824
                     /locus_tag="ACGI5H_001616"
     CDS             23408..23824
                     /locus_tag="ACGI5H_001616"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018112577.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage portal protein"
                     /protein_id="HFG9697326.1"
                     /translation="MNTVEKLLNMDAGKLKMPSSAFELYCKKLDDTLEIECKAIDPER
                     FDEIRMNSMDVNSGDVENINIYELKVNTILESCSIFSNMELVKKFSAITPKELIKKLL
                     LSGEIDKLYEEVNKVNGIDAEGDKKRQKERAKDIKN"
     gene            23851..24000
                     /locus_tag="ACGI5H_001617"
     CDS             23851..24000
                     /locus_tag="ACGI5H_001617"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425680.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9697327.1"
                     /translation="MYLLFKYKGIMPSVSYHILRGEKEIVSVFMDQELDERKEEIKSG
                     VGRLF"
     gene            24004..27393
                     /locus_tag="ACGI5H_001618"
     CDS             24004..27393
                     /locus_tag="ACGI5H_001618"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009899646.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005198 - structural molecule activity
                     [Evidence IEA];
                     GO_process: GO:0016032 - viral process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail tape measure protein"
                     /protein_id="HFG9697328.1"
                     /translation="MSSNTKVLQAIIKMRDEASSTLKRVAANTRALHDSSSQASRALN
                     NVQSNLKSVGTSALKAGGLITAGVGGAFAAATKVGTEFESAMSQVKATFGNSLKPGDF
                     EALSKAARDAGKATTKTAADSANALQYMGLAGWDVQKSMHALMPVLNLSEAASMDLGL
                     ASDLVTDSMSSMCLEVDKVSKSGKVLAGAGLSEYLDKVANASTKSNTSIQQLMEAFNV
                     AGGTFSNLKVPLSEATAIMGILANRGVKGTDAGHALNSIMVNLTTGAGQAGKAMKKLG
                     VSAFDNQGKFKGMSNVLKEVANKTKGMTDEQKNYYLSAIGGKTQLKTLQKLLDGVGNE
                     YDSLKKKIDNSKGALKTMSDVMKDNTKGGLATLKSALEETGITIYYQLKPAIASVVDN
                     LTKMTVWFNNLSEPIKRVITNVMLSVGAFGVLLLTIGAVSLIVSKAIGIFGFFVPIIL
                     RAKVAFRAFVIGMKPLSAVFLAVMGPVGWTITAVIALSVAFTIAYAKSEVFRNKVNSL
                     VKSFTEFAKPIVNFCMPALKQLGEKFKELLSAFGPLFASILNLGSVIMKVLGPVLIGV
                     IGFHIAKLVLILSTLATAFKAVVDTITNVLNGLASILNGVFDLIIGIVTGDSKKMMDG
                     VKQIFDGGTKIIKSIWKGFIDFVTAPIQAIADIADSLFKDKAKWLTDKWRDLRTFLEN
                     PIEATAKISTKTNVNIPGSKAADAAGKSTPNTGGLKQTVANLKGSFSDFKTFIKPMTD
                     SISQGVESGKTKFTELQNKILNDVKPALKVLEDSGVNFKDKFKESITSIKDKFNELKN
                     ILAGNIKTNIDNLVKAFEPLKPHLDNLKDCFDKVKKAITDFFTPAKQVGDTVNKVSQP
                     MDSVKKSTDGIKLSFQSLTQALAPVKAWFQGFMPFLSQIGQQLLPSIGIAIAGVVGGI
                     ILAFTWVLNTLTAIITTVSGIINGIMSFISGIINVIMGLITGNADQTMDGLKQIFDSG
                     VGVIKSIWNGLVDLVSGVLEPVIDLADSLFKDKVKGVKEAWNKLKDFFKHPIKGTIEI
                     FKKGPSLQIGKGADAAGKSPRKAFGINRVPRNDYLIRAHEGEKLLTKQEANQYKRNSS
                     NGSLFLDKLADTIIVREEADIDKIVRKINKKISLAKIGGVL"
     gene            27440..27916
                     /locus_tag="ACGI5H_001619"
     CDS             27440..27916
                     /locus_tag="ACGI5H_001619"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425686.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4352 domain-containing protein"
                     /protein_id="HFG9697329.1"
                     /translation="MNKKILVLTISIILSLSLVGCSTNNSKNRDSKSKQNTEEVKNHK
                     IGEVVDLDGAKVSVKNIRKLETNSNDYAVEIEITNTGDNDLQSDYLENYILKSSDNTT
                     GEAINNQELNGELMFDTIRPGDTLKGEIAFELTKDATPKTLEIAYENVGKYTVFDL"
     gene            27974..28609
                     /locus_tag="ACGI5H_001620"
     CDS             27974..28609
                     /locus_tag="ACGI5H_001620"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425688.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysM peptidoglycan-binding domain-containing
                     protein"
                     /protein_id="HFG9697330.1"
                     /translation="MEIWLRQANNTFRFPVIPPSFEINGSATINTSNILSVGDIAVFG
                     GLGLKTIELSSFFPNQEYSFCNYNGFPKPYDCVNLIESWMKEGYILRFIITETNINFE
                     CIIADFNYREQDYSRDIYFTLSLKEYRRIQISKVNINNDEKLSSEKNVPLTKGFDTKQ
                     KTHKVVEGDTLFKIAKKYYSNGDLWEKIYKANEDEIKDPSVIKNGWVLIIP"
     gene            28850..30367
                     /locus_tag="ACGI5H_001621"
     CDS             28850..30367
                     /locus_tag="ACGI5H_001621"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419653.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NlpC/P60 family protein"
                     /protein_id="HFG9697331.1"
                     /translation="MIIDRSKDSSNNNIDFTAKDMGFLLLQSEVSYNFKDKLVEDIAK
                     QVFVDNKFPLGNLPKTNVKYTKMFIGVTGYDTIMSVYTEASKTTKKKYMIESNLDKFN
                     VIEKGVVTLNITFEEGFNLINTNFSESIENVKNKVLVVDQYGNKISEKINDSIFKDVG
                     VIMQKVIQQQENSTIDIDGEFKGIEKTCSLKGYGDITCVTGRGVKVKDSYTKLIGLFY
                     IDTDKHTWQNGDYQIELELNFENIMDEKSAGQDEQKEDGSEYTGGTEYPAEFTAYCPR
                     KEEGGNTDCRGKKLDPSKKTCAAPMVGAYEKSYYTKDFLNKHPLMRYGDEIQLVTGVS
                     SRDGTYKVNDNGPAIIIEKDGTYHIDILFGNVEEANNFGRRKGKIIIGGYSGNMTEKA
                     KTVISEARKHLGKPYKWGGNGPSSFDCSGLMVYCFKKVNVNLPRTSSQQSKVGKKVEK
                     NNLQAGDLVFFHNPVSHVGLYVGNGEFLHAPQTGDVVKISKLSNRKDFNTARRVL"
     gene            30381..30713
                     /locus_tag="ACGI5H_001622"
     CDS             30381..30713
                     /locus_tag="ACGI5H_001622"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003431637.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2577 family protein"
                     /protein_id="HFG9697332.1"
                     /translation="MADPINEFIGIIRQEGKFHNEPSFFIGKIKSKLPDLKIEINNII
                     LEKEDILIDSWMLDRQIELFDTETSQEHKHEIKNPFIDTFESGNTVIMFKIGEKFAVV
                     SKLVSLDE"
     gene            30706..31140
                     /locus_tag="ACGI5H_001623"
     CDS             30706..31140
                     /locus_tag="ACGI5H_001623"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894588.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2634 domain-containing protein"
                     /protein_id="HFG9697333.1"
                     /translation="MNNTIFPFMGVPEDYISPDNEELPIFKEFAWDFNKDEKIIENGD
                     FKIVERNEAIKVWIYKTIKTDKYVHLIYDWSYGTDIKNLIGQKYTKGLTESEAKRYIQ
                     EALLTNPYILEVNITNAEFEDDNLSISLNVKTIYGEEEITFV"
     gene            31133..32185
                     /locus_tag="ACGI5H_001624"
     CDS             31133..32185
                     /locus_tag="ACGI5H_001624"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429743.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="baseplate J/gp47 family protein"
                     /protein_id="HFG9697334.1"
                     /translation="MYNGQSFSTLNNRTLNNINLPLYKGQGSSLYNIVSPINSELAQL
                     YIELSYIHKRVFIQDNFDDFLDRRVNEFGVYRKLGTEAIGEVTFEGKIGTQIPNGTII
                     SHSDLLFVIIKDITIDENSKLNVSPIQALEIGIKYNLSANTEFKLIEEITGVTKIYNE
                     LDLKGGTEIETDEELKERFYKIQKNQATSGNKAHYQSWALEVEGVYNAKVIPRWDGPG
                     TIKILIYGQNNQSVDNEVLQRCTEHIEEEKPIGPTVTIVTPSTFDINISATLTLENGY
                     DIESIKVVFLDIINSYLIENSREIVYIKVMSLLASIEGIHDIKNLLVNGDVKNIIVDE
                     EKVPAVSSAIFDIEVS"
     gene            32187..32795
                     /locus_tag="ACGI5H_001625"
     CDS             32187..32795
                     /locus_tag="ACGI5H_001625"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015981513.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative phage tail protein"
                     /protein_id="HFG9697335.1"
                     /translation="MKLIDYLPSFANNEIDIQIQEALENELLTLIDEKDDLLEQFFID
                     TATWGLDDWENLLSIKVNYKLDFDTRRSNIKAKMRGKGTTTIEVIKAISEAYTKTNVD
                     VEVFSNLFSFTLSFITNNCSYNTILELDKKIEEIKPAHLEHKFERILFNKNELYTGAA
                     ISTGETVTIYPYVPRNLESFGEIAICSGNDRALEKVTLYPKK"
     gene            32812..33594
                     /locus_tag="ACGI5H_001626"
     CDS             32812..33594
                     /locus_tag="ACGI5H_001626"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009900142.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HFG9697336.1"
                     /translation="MTEQQYFTLVTDIGKAAIANASITGEKVDFAKIKVGDGGGSSYT
                     PNESQTALKNVVWESTLEHAQGDKDNPNWVVIQKFIPGDVGGFEIREVGLFDSKDQLL
                     AISSYPTTYKPTADSGTVKELLIKVILVVSNVANINLKVDPTVILATLKDIQELDTKI
                     DTTKTELTSNIETAKTELNTKIGDTTQLTTTDKTNIVSALNEVKTSVDSIETTADKTS
                     IKDTDNLFESDNVEGALKEVMQEVKGNRSSIISTINSNLIPM"
     gene            33611..35056
                     /locus_tag="ACGI5H_001627"
     CDS             33611..35056
                     /locus_tag="ACGI5H_001627"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894405.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9697337.1"
                     /translation="MKIWKYNRTVKKRRGVYTELDILAQRYEFEADGKLYTAYFHLYT
                     NKNIDIFRDKDLYKESYMMSYRVGNVTTDIDDVVQQTTTVRFIPDPVIDIVIDNISRG
                     CEINYRIIDNEPSVKFIVTEKLNGTIIETKTNSSDNNYKLKLTDEQIVPLAFNSQNSI
                     VIEISTEDGGLVTSKTVTFTRTNNKPTILVNSYSSNSAKFTASDLDNNLSKIEWYLDD
                     VLKETITTDLTAEKTINYEFTDNAIHTLKIVATDAENATVEKVLSISKEIMPLQSDAS
                     LSDISTKLIEIGEGFRNGKTSIINTLALKNIEASLNNTLVELSEKIKTSFDSSDASVQ
                     DLQNRITELNNQLSRRKKWATGRYTFTREEDTINFRMVDGDSLSAVKKLIIPINLDFV
                     PSVIIIDKMFLGSYVPAQDVQFNCVSNLADFTLGRRFYNKQWICTSSIKLDSVTQNSF
                     TLSLQKVVPFDKVSSTIFSIINTGFAWRAYE"
     gene            35080..35427
                     /locus_tag="ACGI5H_001628"
     CDS             35080..35427
                     /locus_tag="ACGI5H_001628"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429875.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9697338.1"
                     /translation="MNRNNRIIYDQTGKIWLQTGEAIGDIQELSEITELNFIDVEFGS
                     IDYSKQYIESINPVTKELNIKNIEVVLTDEQKRLEVLEKELNMLKEENKNRDSEIVNT
                     AFEVGNIKLNNNL"
     gene            35439..35609
                     /locus_tag="ACGI5H_001629"
     CDS             35439..35609
                     /locus_tag="ACGI5H_001629"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894401.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9697339.1"
                     /translation="MYNLLKLMIEQKNYSTKEDLQHKMDVFYAVNRITEEQYLELTGL
                     LNKEETPVEPTI"
     gene            35639..36208
                     /locus_tag="ACGI5H_001630"
     CDS             35639..36208
                     /locus_tag="ACGI5H_001630"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728849.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9697340.1"
                     /translation="MTFKELVSKVRNLVLEAKNVTIEDTENKFTSENVEGALKECIDR
                     ADLAFQSADSGKELIATAIGSPATSEQTFQEYANYIAGFKNTISQLNSKYKYTSGTFT
                     YYTGAYPNGLNIGFRPDIISYTAINAVEEKYYCVYTPLFYLFYNYTTGEKYLDVNHNR
                     YGITFTDNGWIPRNPVNNGVYSYIAAKCR"
     gene            36267..36695
                     /locus_tag="ACGI5H_001631"
     CDS             36267..36695
                     /locus_tag="ACGI5H_001631"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418172.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phage holin family protein"
                     /protein_id="HFG9697341.1"
                     /translation="MNVTIVFLATNIFIKLVILAIAFDTLLGCLRAIKTHQFNSSFGI
                     NGGIRKVAMIACIFFLAVVDILTKFNFLFMLPQDWVDFLRLNHLGISEFFSILFILYE
                     SVSILKNMYLCGLPVPKRLKEKIGSLLDTMTDELNVKGGK"
     gene            36699..37529
                     /locus_tag="ACGI5H_001632"
     CDS             36699..37529
                     /locus_tag="ACGI5H_001632"
                     /EC_number="3.5.1.28"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003415961.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008745 - N-acetylmuramoyl-L-alanine
                     amidase activity [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase"
                     /protein_id="HFG9697342.1"
                     /translation="MKICITVGHSILKSGACTSADGVVNEYQYNKSLAPVLADIFRKE
                     GHKVDVIICPEKQFKTKSEEKSYKIPRVNAGGYDLLIELHLNASDRQGKGSEVLYYSN
                     KGLEYATRICKKLGTVFKNRGAKLDKSLYILNSSKPTAILIESFFCDNKEDYEKAKKL
                     GYEGMAKLIVEGVLNKSIESNEVKQMYKHTIVYSGDDRVSADILGLYYKRAKESYLVI
                     DIKDYKPHRTQNLYVIGGVTCNKMKEMSKTTGEKFTQLYGNDVWSTMDKVIEFVKEKL
                     "
     gene            37601..38707
                     /locus_tag="ACGI5H_001633"
     CDS             37601..38707
                     /locus_tag="ACGI5H_001633"
                     /EC_number="2.1.1.37"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003886 - DNA
                     (cytosine-5-)-methyltransferase activity [Evidence IEA];
                     GO_function: GO:0008168 - methyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:1904047 - S-adenosyl-L-methionine binding
                     [Evidence IEA];
                     GO_process: GO:0006304 - DNA modification [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA cytosine methyltransferase"
                     /protein_id="HFG9697343.1"
                     /translation="MLTFLDLFAGIGGFRLAMERAGHKCVGHCEYDKFANLSYKAMHN
                     PKEDEWFEKDIREIRAENIPKADVWCFGFPCQDISIAGNKLGFKGNRSSLFFSVTKLI
                     RELKEEDRPKYLLIENVKNLLSVNRGFDFAKLLIELDEIGYNAEWQNLNSKNFRVPQN
                     RDRIYIVGHLRRRSTREVFPITGTSRKTTLEQLNNPNHSSNRIYNSNGLSKCLLSKGG
                     NNTGLYRVGNINPSGNGAGGQVYSSEGFSPTLTTGKGESPKILIKENTKKGYIKASIG
                     DGIRLDHIEGKTGRGRVQHKKSCTLTTASNAGVIGKKFRVRRLTPKECFRLQGFPDDY
                     YDRAASVCSETQLYKQAGNSVTVDVVEEIAKKLK"
     gene            38914..39180
                     /locus_tag="ACGI5H_001634"
     CDS             38914..39180
                     /locus_tag="ACGI5H_001634"
                     /inference="COORDINATES: protein motif:HMM:NF015898.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0045892 - negative regulation of
                     DNA-templated transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="BlaI/MecI/CopY family transcriptional regulator"
                     /protein_id="HFG9697344.1"
                     /translation="MSKKEIIRICNEKHNWRKSATKTLLKRLVKKRVLLKRIKIFHIY
                     YIPIVTEKEYFKYKINDLEPDYLDEYFIRLMSTVHKFKNLDEED"
     gene            complement(39191..39706)
                     /locus_tag="ACGI5H_001635"
     CDS             complement(39191..39706)
                     /locus_tag="ACGI5H_001635"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009899650.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9697345.1"
                     /translation="MTWSDLKEKNINEVVDCINNKLSEFESLKKVGDELGANESTIRK
                     WLNKKGYKRTGNKFVEDNKSYDDKYHIDSISSKIDDDIKYLSSEIDNIKNVLEWFKTK
                     DDSYHICVIKENDISIDLPDQSIKRTTVRINNTVWEMFNKFADENKHYDKHDLLSQLL
                     LESLLKYVKSR"
     gene            complement(39789..40694)
                     /locus_tag="ACGI5H_001636"
     CDS             complement(39789..40694)
                     /locus_tag="ACGI5H_001636"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428605.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATPase"
                     /protein_id="HFG9697346.1"
                     /translation="MSKLGIDIGNYAVKTSTDDIFESKVTEVKNFGSDSDSIKIGNKT
                     YYLGEGDEEINIVKYEKENFLPLLLGAICRNTDDEIVDLGLGLPVKQFAGLRKNLIEK
                     LQGKEYHVEFTRGNETTKRDITIRSIQTFPEGVTGYLYYAKDIVDQIAGRDVVLVDIG
                     GKTTDIALVQGNKATDPYSINVGTINIYDAIKKSLEMDERFLGKVEIKREKIQDYINK
                     GFYLNGEKQDIKKNIDASISLFKEIYNELKLNYPVSTAAVVVMGGGAKLLGEAFKKNI
                     PGIIVMSDVDKHVFANAKGYKKMMK"
     gene            complement(40714..40917)
                     /locus_tag="ACGI5H_001637"
     CDS             complement(40714..40917)
                     /locus_tag="ACGI5H_001637"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428606.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9697347.1"
                     /translation="MSRIVLTFKNNDKEKAIEKFLDEKLSATAYLKELVWEKMQEKKD
                     NAVVEQKKEIEDPANNFDFGSLE"
     gene            complement(41166..41624)
                     /locus_tag="ACGI5H_001638"
     CDS             complement(41166..41624)
                     /locus_tag="ACGI5H_001638"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9697348.1"
                     /translation="MKKTIALLLTLCAVMIPFTAFADGNDYEGTGNSQTVELIGQPNS
                     DSPSTKSVVVPGGTANLTAMSGGQLSWRVTSTLGNILGFEGNIDVYKAGKIVSSQYVG
                     FRLAGTTKTGVVTFKGLKKGSYIAKFKGKGVCTGGIILFSSPAEASFTIR"
     gene            complement(41659..41961)
                     /locus_tag="ACGI5H_001639"
     CDS             complement(41659..41961)
                     /locus_tag="ACGI5H_001639"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894413.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9697349.1"
                     /translation="MEVNLHTGKDEFFKSHEVAKNYIGGLYKLIDVYKFSMESVSVLT
                     RIDLDKLNNFYAGEASLNYDELCLIESVIITPLVGAFETAEHNYNMIIKARKERKL"
     gene            complement(42349..42501)
                     /locus_tag="ACGI5H_001640"
     CDS             complement(42349..42501)
                     /locus_tag="ACGI5H_001640"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894412.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9697350.1"
                     /translation="MDNFLFNVLASLTASVVVYLISELFKKAKSHSRAKSDLQVEFKF
                     IFKFKK"
     gene            complement(42621..43355)
                     /locus_tag="ACGI5H_001641"
     CDS             complement(42621..43355)
                     /locus_tag="ACGI5H_001641"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894411.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GIY-YIG nuclease family protein"
                     /protein_id="HFG9697351.1"
                     /translation="MYYVYKYINLDTEECLYVGKTENICDRHASHLSNKKENWCNKNL
                     RFEYIELDNKYTMDFYEIYLINKLEPKFNITGKGEMDIAKTSFSYNGQWVIYSERDLM
                     SSLASKRCGINYEVNAKMLGIMRKLKKISSNEEIFIGNENIRIKYYFETVLEGINLEP
                     CILSVAYKTLKESTVGTVISVKREYLSENVCLIIDSIFLNEIMKDPLMSKSDIKDLNS
                     QVNDILKIIGVDCEWNKLSDYCSANS"
     gene            complement(43375..44562)
                     /locus_tag="ACGI5H_001642"
     CDS             complement(43375..44562)
                     /locus_tag="ACGI5H_001642"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894410.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003887 - DNA-directed DNA polymerase
                     activity [Evidence IEA];
                     GO_process: GO:0006270 - DNA replication initiation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiation protein"
                     /protein_id="HFG9697352.1"
                     /translation="MEKKEILMQPNNLIKSKYDFTNVENKLFYKILFNAQKQQNSSYV
                     TTISKEELKVFMKNNNDYEHKNIKEILNMFQQSVLEFDYIEETTGKLKTFGSGLINTY
                     ELDHTDQIYTIMMHEVLYNHITDFVKMQKKKNGYTAINLSVLFNFRGAYTQRLYTLFR
                     LWSRENKEVEIKYKLDELRFYLKLKDNVYPEYKYFKQNVLKRAMNEINKKGNMVVSIK
                     EEKRKNRKIDEIIFSVIDYEPRKYFDKDILVEDYIPKKKQDNEVSFSFYIPNENIFTT
                     GTIKLFKEDFKEFDFKKDVYLNAFNKSIAIAFERDNTDIINTKNYDFFKSTLSNKISE
                     VIIHQKDDLKFKEELDKYWDDEDVKKEEREVDYSKDPVRLETVRRNLFDQGLVNEEGY
                     YYK"
     gene            44915..45604
                     /locus_tag="ACGI5H_001643"
     CDS             44915..45604
                     /locus_tag="ACGI5H_001643"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425609.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HTH domain-containing protein"
                     /protein_id="HFG9697353.1"
                     /translation="MLENRKQIQKEIYLPIATYCLKDKQYYIKEYGALLIKSAENSDI
                     FNTHKNRILYKNKLDIQEIANELNVNKATIQRNIKKLEKLDFKILKIENTLNGIVYCL
                     PSENNIDLNKFALINYEMLKKMVNKFKSNTIKVYFLLKTITTETNFKPATNSFIAENI
                     GLSSKSKNNLDIITSSVKTLEENKYIETKKVNVYEYDKEKLREVPKIRKVYRICNFDE
                     WKKEIDKNKVY"
     gene            complement(45753..46136)
                     /locus_tag="ACGI5H_001644"
     CDS             complement(45753..46136)
                     /locus_tag="ACGI5H_001644"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425612.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0045892 - negative regulation of
                     DNA-templated transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="BlaI/MecI/CopY family transcriptional regulator"
                     /protein_id="HFG9697354.1"
                     /translation="MKIKKIPESELLVMMFIWDSEDKEVASTEILKTLGEKYEWKKST
                     MLTFLRRLVGRGFLEVVKKDRFTYYKALIEKEEYLKVETKSFFSFFHKNSFESFISAL
                     HDDEEVSENKLKSLEKFIEDWEEDK"
BASE COUNT        18578 a         5376 c         7711 g        14583 t
ORIGIN      
        1 aaaaaaaaat taagcaggag taaaaaaaat aaaatattat caaaatttat caatataaaa
       61 agaaatataa gtataaattt ttctctttgt atattgattg tatacaattc tatttttgta
      121 aaattaaatt ttaaaaaata atcaaaaatg gtaaattttg acatttgctt aatgtcaaat
      181 taggtgttac aattgtagca taaagaagat atatatcgaa ataatacata taaaactacg
      241 tacgtaaaat atttttaaaa ataatcaaaa atcttaattt tcaatattga atacaattaa
      301 attttcaaac tcatctaggg catgacatac aaaagcaaaa aacattaatt tagtatctga
      361 taaaaattta aaaattgtaa aagggggaag tctgttattt ttcagaagca atgtaattgt
      421 aaaaatataa atcagaatat tttgaaaata tgggggataa acttatgatg gatttagaaa
      481 aggaaaaaca tgaaataatt gaaattataa aaaaattaaa tattgataaa gataaaagga
      541 atttattgat gataaaaaat tatatccttg gacttttaaa aaaatagaag aatagcaatt
      601 gctattcttc tatttctagt aaggaatcta tcattttatc aaatacagtc agatattttt
      661 tattcaattt gaacatttta gttataattt ctctttctac ttcattttcc attttactta
      721 gttcaccaac aagatgggca aattgctcat ctaattcttt gataaaaaac atctctccaa
      781 ctccatgctt aagccattct tcagatatgc tccaagtctt gcaaatgtcg ttcaaagttc
      841 tttcgcttgc atttctttta ccattttcaa ttaaagatat tgtgtttctt tttaaattta
      901 gtttattagc aaactcttct tggcttaaat tgagatttaa tcttagttct cttattcttt
      961 tgttttctgg tttcatttca tctatcatta ttatccctcc atatgaaata ttatatttta
     1021 aaagtgctta caagtcaaca aaaataaaag aaaaaggtat tacaaaatag ttgacttgta
     1081 agcagacatg taatataatt gtattacaca atcaacaaaa gcgaggtgat tgaaaatgac
     1141 tgatataaat aaaattagag aagaaatata tagaaaattg gagttacttg gccctgcaaa
     1201 actaaaatta gcattgacta aagtagatat attaaaagaa atacaagaca ttgaagatga
     1261 aaataatata caaaattaaa ggggtgaaaa gattgaaaat ctcagatttt aataaaaatc
     1321 aaataggatc agcagttcaa ttacaagata taaggtttga tacaaaagct gattgcatca
     1381 ttacgaaagt agaaaagaat gaaatactag tcatgtatta tgaaaaagaa acagaggaaa
     1441 tagcatataa aactttgact aaagaagatc taatacttga tgactataaa cttaagttat
     1501 tatcttaaag taatttcaga agggaggtga taactttgga tcttttgaag gatgcaagaa
     1561 aaaaagagtg gttttggctg gaaaatgatt tgattgatag agaagatttg agcatctatg
     1621 aaaaaatgat ttacattgtc ttagctagat atagtaacga agaaagttct tgtttcccaa
     1681 gttataaaac aatatcagaa aaagcaggtt gcagtataag gcaagtatct aatattttga
     1741 atgaattaga gaataaggaa ctaataataa gagaaaatcg taaccacgaa ggcaaaaaag
     1801 agaaaaacag taacttatat ttcttaatat cttcaaaagc aaaggtacag aatgaagtgc
     1861 ctaacgttag gcatgaggtg cctaacccta tggcaccagg tgccttacat gttaggcatg
     1921 aggtgcctag taaaaagact tataataaaa agacttatat aaaaagtaat accactacac
     1981 aaaaagaatc taaaactgat tatttagacc tatcattctt ggacttagat atagaaaaag
     2041 taaaactaac taaagatgaa tatgacaaac ttataagcaa gtttgggaag aaatacatac
     2101 acgataaaat tgttagttta gaaaactata tcataaatgg taaagggagt aggtataaga
     2161 gccactatag ggctttgctg acttggggga atggagatgc tagtaaaggt atagtaccag
     2221 aagttacaaa gactaagaat cctcttagtg gatttaaaga actttaaaaa ctaaatagta
     2281 aggaggtaga taggatgaat gaaaaagaag agactgttta tttgaatagt tctaatgtga
     2341 agttattctt aggcgttagg gatattaagg aatttgagga attgatagaa aatgtcaatg
     2401 agcgaatttg tcaactccaa gaatcgatta ataaacttgc ccaatttaat attgagttcg
     2461 atattaagtc agatatttag ttaagtataa attaggaggt tgcctatgaa agatgaaaag
     2521 ttagaactta ctgaaaaaga tttacactgt attgcaagac atttacaaaa tgaagttatg
     2581 gagatggtgt ttagagggaa tatagaagcc cctacatcat gcgaagtttg cgattacttg
     2641 caagaatgca aggactattt cacccatata gacactttta taaaattaag tgaaatgaca
     2701 ggtgtagata tttttactaa ataaatttag taaattaaaa ttttagtatt gtaattgacg
     2761 tgctttttta aaaagaggac agttgctatt agcagtcatt atttgaattt tgcaaatgta
     2821 atttttatta cattcgcatt ctaaaagttt tgatccagtg aatccaggaa aagttttata
     2881 ttcaccagaa aattcaactt tatcgtcaat aagagagcat ttttctctta aggttttaat
     2941 tttgcacata ttcatcacca ccctataatt aatttgaaca tactgtcaat atgctccgat
     3001 taattataac atgcaaatta tcatgatgta gaattaaagc ataggtcaat taaatttagt
     3061 tataaaatca atgaaacaga taaataatta aatgttaaat aaattagggg gttgttcatg
     3121 aaagaggaaa agttagaact tactgaaaaa gaattgcatt gtattgcaag acatttgcaa
     3181 aatgaagtta tggagatggt gtttagaggg aatatagaag cccccacatc atgtgaagtt
     3241 tgcgattacc tgcaagaatg tgagggagat tttacctgta tgtatcattc ttttactaaa
     3301 ttaagcaaaa taacaggtgt aaaagtgact gcatttaagt attgttttcc agatgaaaat
     3361 cccaaagcta ctatctaaga agttttttta gaataggaca ttcttcatta gaagaagagt
     3421 cgcaaatatg acttccatca catctagttg acattaactt agatccaaaa gtacctggag
     3481 gagctgaata ttcgcaagta agagaaatgg tttcgtttat tacaggacat tctttgctta
     3541 taactcgata ttggctcata ctctcaccac ctttctaatt aatttaaaca tattggaagt
     3601 atgtttaaat taattatagc atgtaaatta tcatggtgta gaatagtttc aaatcaaaag
     3661 aagcaactaa atagttaaag acaggaggta tgctaagtgg aaagaaaaaa acatgaattt
     3721 acagatcaag atatacaaag acttattgaa ggattaagaa ctgatccaaa aataagagaa
     3781 atgatattta aaagtaaagg ttgtgaaact agaacaagta caagaagtaa atgcgaacaa
     3841 tttgttgaag aaaaacttgc ttatagaagt tatggatttg aaactccaaa atactatgca
     3901 aaacttattg ccgacataat tgatatttta gtttacaaaa atgttccaag agatcgtatt
     3961 tgtggggtat tgtatgacgt cgaaagggtg attcctttag ttgtgacatt ttaataataa
     4021 gctgggggtg attaaatgaa ttactcttta gaagcagagc aaaacattct aggaagtttt
     4081 cttataaatg actctatagg ttacaaaata agggaattaa aagaaaatga tttctacttt
     4141 gagtcacata aaattatttt atcttgcatg aagaaaataa ttgactcaaa taaaccacta
     4201 gatcttttgc ttttaaaaaa tgaattagaa aaaatagata gattagtaga tattggaggc
     4261 gttagttaca ttaccagttt aacaactata gttataacta cttcaaacat agatcactat
     4321 ataaaaatca taaaagagaa gttacttaaa agacaaattt cagagttagc aaatgaatta
     4381 attaataatt caaattcaga tacaagtata gatgaattga ttatagatat aaacgattta
     4441 aaagcacttg tgacgacgag cagtagtgta aatgataatt acattgacgc atcaaaaata
     4501 aaacgtgaaa aaggcgtaca caagtccata gacacgggtt ttaataaact aaacaatatg
     4561 ctagatggat ttagatatgg aactcttaca attttaactg gtaaacctgc atctggtaaa
     4621 tcaactatag ttaaccagtt tatagcacaa gcaattacga atggagagaa agcatttttg
     4681 tattctggag aattaccctc tttcatgtct atggattggt ttagaaaaac tgtagctaat
     4741 gattatcaca taaaagaata taaaagtgtc tatggaggaa catacacaga tattccagat
     4801 tacgccgttg agcttatatc agactggata gaagataaat tttttctcta tgatgaagat
     4861 gcaataagtg atgaagtaaa tctactaaat accatagagc atttatattt aaaaaaaggg
     4921 gttaggttct ttgttcttga caatctaatg acaataaaaa ctggcaataa ggcagataaa
     4981 tatgagagac aagagcagat agtaagcaac ttaaaaaatc tcgctaaaaa atataactta
     5041 gtaatagttt tagttgcaca tcctcgtaaa aatatgggtg acatgaagcc aactatgtat
     5101 gatgtgtctg gagcaagtga gattgttaat tatgcagatt atattttatc aacttacaga
     5161 gttgttgatg aagaagaaga gacagacgac acttatttat taattttaaa aaatagaata
     5221 acaggaaaac agaatataag ttttaaaatg aatttttcag aaagaagaaa aagactttac
     5281 acgactagtg aggagttaaa cagagattac aaatatgatg taaataaaca atatgttcaa
     5341 gtagaaattc cagaagatgt attttaaaaa aagtataaaa aataggaaat tttattaagt
     5401 aatgatttta taagaaaaac caatattgaa taatttaaaa attcaatatt gaaaaaaatc
     5461 atttttcaat attgaaaaac ggattttgaa aaagtattga atttcaatac taaaaaaagt
     5521 ttgaaaatat agcatttaca aggtttatat aaattaattt cctgacaatg tacacacagg
     5581 tttagatatg ctagcaaaaa aacttaaaag tagtgtaagg ataaaaaggc tatataaatt
     5641 tataaaaaga tttaaaagtg ttattaaatt agagctaaag tttattaatt aatttcctcg
     5701 tagaaaaata ttattttaaa taaataaagg agtgatttta catgatagca ttagaaaaat
     5761 ttgcaggtgg agttctaaaa gaaaagttta atacagagtt acaaaaagtt ttagataaca
     5821 ttgcagatcc aaatacagat tttaaaaaaa caagaaaaat tagtttagag atagtgttta
     5881 aagcaaatga agatagagat cttgctgaag tagatataaa atccaaagca actatagtag
     5941 aagcaaaggc tacaacaact aaagttctga taggaaaaga tttagagaca ggaagagttg
     6001 aagcgtctga atttaaaaat caagtagcag ggcagttggt catggatatt ccagatagtg
     6061 aagaaactaa tgaaacagaa gaaaatagtg ctggtgtaat tgatttcaga aatgcaagtt
     6121 caaagtagtt taagaaagta agtaaaatat aaatttaaat aaaaaaggag aataaaaaaa
     6181 atgataagaa atgcaatgga atatttagtt aagttaggaa aaagagaaac agtatgtgta
     6241 gatgggttta agtacacaac agatgcatta gaaataataa aagaaccaaa agctaatgaa
     6301 ttagaaataa ctacattgag tggtttagta gattatataa aaagtggcat agatcataag
     6361 gcagatgagt tgttattaat acaagttcta actccaagaa aagtgctttt aaaatctcct
     6421 ttgagaaaaa atagagatag agagacatat attgaatgtg ttgcactact accagagaaa
     6481 agatttgaca gacctttaga cttagatagt tttaacataa tgctacaatc agcatttata
     6541 aagaataatg atagagatac acttttaaaa attgcaggaa atatccaaga atctacagta
     6601 aaaaatgtgg gagatgatgg agtttctcag tctgtaacaa taaaaacagg cgtagctagt
     6661 gtatcagaag caatagtccc aaacagagta aagttaattc cttatcgcac tttccaagag
     6721 atagagcaac cagaaagtga gtttattttc agaatgagtt ctggaccagc agcaggatta
     6781 tatgaagcag atggtggagc atggaaaaat caagcaatgt taaacattaa agcgtacttg
     6841 caagaagaat taaaagattt taaaaatgta aatataattg cttaattgaa aatctaagag
     6901 ggcttacaat aagtcctctt agtaaaaaag gaggggatta gatgaaaatg atttctcata
     6961 tgaacatttt agaaagagca gaatttacag ataaaatagc taatgcaatc atgtctgcaa
     7021 ataaagaaat tgaaagaggc tgtgccttta atgaagcagt tgagattgta aaacaaatgg
     7081 aatatagaga aaataaatac aatgaaggag atattgcaat atgaataatg tagttttagt
     7141 tggaagatta gcaagagatc cagaattaag atatatacca gagtatggta ctccagttgc
     7201 tacttttgca ttggcagttg ataggggtta tacaaaaaag gatggaacta gagaagtcga
     7261 ttttatacca attgaagtta tgggaggatc cgcagaattt tgtgctaatt atctcgcaaa
     7321 aggaagaatg gtttcaattc aaggccaaat aaggatagaa aaatatgaaa aagatggaga
     7381 gaaaaaaact ttcacaaaag taagaacaaa aattgttaat gcgcttgatc gcaagccaaa
     7441 ggatgaagaa aaagaaatta gttttcaagt tttagatgat gaagatattc cattttaaat
     7501 tggatggtga ttatgtgaga agtttagagg agagaaataa attagttgaa gaaaatataa
     7561 attttgtatg gtttattata agaagatatt tcaaagtatt tatttcaaaa tatccatatc
     7621 ttcaagatga tacattttca gaaggatgta ttggattatg taaagcagca gattattttg
     7681 atagtaaaaa aggtattgaa tttaccactt ttgcagctgt gtgtataaaa ggtcaaatat
     7741 ttaaatttat aagtaggtat gttaaaaaac attacagagc agatatagat agttttgaaa
     7801 aatgcatcta taaaaatact catggtgaag aaataagaat agaagataga ttggctggta
     7861 atgaaaatgt agatatagaa aatgttcatg ttattagatc ttgtataaaa agaagtaaaa
     7921 tagaagatat acagaaaata acatacttaa gggaaaaagg atacactcaa aaagaaatag
     7981 gcaaaatact taggactaac caaatgacaa tatgcaggaa gcttggaaaa ttaaaatctg
     8041 aaattaatat actaggaaaa taatataata atttaagttc attggaggca aaatgaagac
     8101 taaaataatt ggtggtaggg aaaatcagtg cccactttgt aatggtagtg tatttaagat
     8161 tgaaacatca attggaatag tatggcaatg taaggattgt ggatgtatgt atcaagatat
     8221 gaattgtaaa gaaaacaaaa ggaggcatta agtatggctt gtgttataaa gtgtgatttt
     8281 tgtggtgaaa caatagcaga aattctaaac ataaaggtat tcagaattga tgatgaaggt
     8341 aatataatga gtatcggaaa agatgtatgt gacaaatgtt atgacagatt atttagaagt
     8401 aacttgaata agaagatgac taattatgaa aagataaaaa atatgagcaa aatagaaatg
     8461 gctgaatttc ttgcaaatgg cggaagtgga tgtactagtt gtgcttatga ttttcaagaa
     8521 tgcttaggcg gatgtttaga aggtagaaaa aaatggcttg aaagtgaggc gatgaaataa
     8581 tgaaaaagac gttaataatc gtaggagtag ttatttcaat attaattatg tttgcttgct
     8641 tgttcttagt aactaaaaat aaagcaattg atttagaaga gcaggttcaa tcagcaactg
     8701 catctgtaga ggtgcaagaa aaaaggagaa ttgatttaat taagaacata gtagactgtg
     8761 taaaagacta tgctaaatat gaaaatagaa cattaaaaga agtaactgac atgagagtaa
     8821 gtgcaaatga tgaatctatc aaggaagcaa aattaaatat acaagcagta gcagagaagt
     8881 acccagattt aaaagctaat gaaaattata agcaactaat gagtgagttg agtataacag
     8941 aaaatatgat tgcacaacat agagaaaatt ataatatgca agttcgcaat tacaataaat
     9001 atataagaaa atttccagca aatttaattc taaatagtat gggatatgaa aaaatagaat
     9061 ctaaatatac tgaatataaa gcaaaagagg atgcacctca aaatttattt gattaagagg
     9121 tgcacatatg aaatttaaaa cttttgaaat aactaagaga gaatttttag tgagcataat
     9181 aattgcttgc atgatgattg tgcttggatt tttcattgat gataaagttc aatcaaaatt
     9241 tttagaagat aatgaaagat attacaaagc aactaaaata aataatgaca aagatctctt
     9301 tgattatgct atggaaacaa gtgcgggaga ttctttgata agtggaagat ttaaaagtgt
     9361 agattctgta tctatagaag aattaaaagg ggactattgg tttatagaaa gaacggaaga
     9421 aaaatacact atgcatacta gagtggttac cactaaagac agtaaaggcc attcacataa
     9481 atatactgaa acatattgga cttgggatta ccatgattca atagagaaaa aatgtaataa
     9541 atttaatttc atgggtaaag agtttgatgc gaaagtaatt actaatttat ctaaagagag
     9601 attggcatta aagaaagata tatttaaaaa taataatctt aaaataaaag gtaattatgc
     9661 ttacattaat aataagagaa ggtactatta tgaagttata ccgaaagaat ttaatggtac
     9721 tatgtatgct aatttaaaaa ataatactat agcgaatcca gctgataaaa acataaaagt
     9781 ttttaagggt gagtctatac agaatgtttt agaaaataat aattttaata cagggttttt
     9841 taaagtagtg ttttggatca tctggatatt aataactaca atcattatat atgtatttta
     9901 ttatttaaaa aatgattggc ttgaagataa ataaagatgt aagaggagaa gatcaggtat
     9961 gaaatgtaag gtgtaccatg ctattaaaaa tataaaagat gcaaatgagt taattgatag
    10021 atttgaaacg gaaaatatat tctttgaatt aaatgacata gataatgaaa atgtcttaaa
    10081 tggagaaatg aatttaactg atatagaaga tattgcatca ttgcaattta tattagatgg
    10141 agatttattt atatttagta gttgtgatga aatgatattt atgaataaat acactcaaaa
    10201 agagttggga cttcaataaa tgaatgaggg gagatactaa agatggattt aaagttaatt
    10261 agcagtatac ctaattggaa ggtagaagat cagttggcaa aaattgatga agaggtaact
    10321 gagtttaaaa atgctataga tacaggaata actaaagata taattgcaga aggattagat
    10381 gtttgtcaaa ctattttaac aatgtttcaa gttttagaaa tagaaaacta tattactgaa
    10441 ggagtagaga cacataataa gaaactaaat ggaagaggat gggatctcaa agaaatagga
    10501 gacgatatac ttaatttaat taaaaattca atgattaatg aattgattaa tatgaacaag
    10561 aaattaaaat gccttgatga aaaagaattt aatgcaaaaa tacaattttt agatgtagat
    10621 aaactatgga atttgtgcat gcctttagtt aacttaagta ctataaaagg agttaatgaa
    10681 agcattgatg aaatgaaaat gggagagttt ctaaaaaata ttaattaaag taaggagata
    10741 atataatatg ttgatagaag taactgaaaa taatagagaa ttaaaagtag gagatattgt
    10801 tgaaattaat ggtggtaata agttatatat gattctttct ttaaaggaaa caataggtgg
    10861 gtatgttatt ataaatatgc agaatggata tggttcattt ggtgcttata aaagtttaag
    10921 tcaactagaa ttagacttga aggtaagagg ttataaatta tatagttctg atgattacaa
    10981 gttgcaatta gtgcctagag aataagatat atttcaaaaa agaaaaaaag gagcattact
    11041 tcacgctcct gcttgtcaaa attctaaaac cgtcatcaca acatcattat aacataatta
    11101 ggagtgtgag gtaatgcaat ctagtaaaaa agacaatttg tttagtagtg cagaaggtaa
    11161 gttatatgat tataaaaaaa taaaagcgga aatagaaaaa atagacattg atatgcagat
    11221 gataaaaaac gactacagag gatgtagtgg agttgaaatt aaagaaaaga caggcaagac
    11281 atatgatatt aaaagtgtaa ttgaaataga gactgaagaa aaagaaaaga aaattgcctt
    11341 aaaagaaaaa gagaagagac ataaagagtt gataatagaa aaaatagata atgcaatgaa
    11401 aatattaagt gaagaagaaa aaaagatagt acagtataaa tacttttcaa gtagcaggac
    11461 atcttgggaa tatgttggca gaatgattgg tttttcagcg agtaagtgta agcaaatgag
    11521 gtttgatatt atagataaga taaaaggatt gctataaaaa tgtccgattt gtgacgattt
    11581 taaaccgatt tatgtctgtt ttgtgtctaa aaaatgtccg gtttgtgacc aatttatgtc
    11641 tgttttgtgt cttttaatca tgataagatt gtattgtgag aaaaatatat ttaataaaaa
    11701 tggcttggaa tttacgttct aagtcttttt tattgtctag agaggtgttg aagattaaac
    11761 gtgatataac agaagaaatt tcaagtgctg catatgtacc agacaatcta aagtattacg
    11821 acaatgtaat gaaagaaact cctggtatgt atggaagaga atgttcttta gattttataa
    11881 agaaaaagca agaaaaactc ttgaaactaa aaaagaaggt taagaaaaat tatgattcta
    11941 atattaataa gatagactca tatctaaaaa ttttagagaa aagtataatt gatgagtctg
    12001 atcacgttga gttggttgta tttaaattat atttgcaatt agaaaatgtt gtaaaagtaa
    12061 ctgaaactgt aaacgactta ggatttagaa taaagactaa cacttatgca agagaaagaa
    12121 aatatagtac aaatgatata acctctataa tcacagatcc ttttactgat gtagttgagg
    12181 acttaaaaat attagttcaa gagaggcaaa gaaaaaatta ttatggaaat aaggagtgtt
    12241 tttaatgaat ggaagcacat agtggacaaa aggttaatcc cataaaagat atagaggatg
    12301 tatttagact tttaaatttt ctagaagaat ggaatgaaag aaactattta ttagccctct
    12361 ttggaatgtg tactggactt agggtagggg atatattagc acttaaagtt gcagatgtaa
    12421 cagacttaaa actcgataaa aaaggaaata aaataagagt atctaaggat tggattagag
    12481 ttatcgaaga aaaaagagac tataatagag aggttttttt atctgatgta ataaaaagtg
    12541 ctatagaaaa ttatactcaa gataaaccag gagaagaatt tttatttaaa agtggcaaga
    12601 ggaagaaatt taatagacct atccaaacaa gacaagcagg aagaataata aaaggagcag
    12661 caaaaaaggt aggaataaaa gaaaatgttg caacacactc tttaagaaaa acatttgcaa
    12721 ggcatattta tgatgaagaa gagaataaga cttatgcatt agaacttata aggaagattc
    12781 taggacataa gacaatagaa atgactagaa gatatatagg aatagataag gatgaagaag
    12841 taaaagcaat aactaaattt actaataagt taaagaaaag aaaaagaaat taaaatatct
    12901 tgtattttat ctaaaattta atatgttacg tttttcaaca acaggacatt attagaatgc
    12961 aaagagcctt aacaatagag tttacaagga atagaataga tttattaaaa tgtctgaaaa
    13021 tatatattaa aggtcattta ttcaagggat ttatagggat gtagatattt aaatgtttat
    13081 ttagaagctg agtaaagagg tgattaattg gatgtgaatg aagttgaaat aatcgatagt
    13141 agctatgaaa aaggtaaaga gttgacagaa gatcagtgca atatggtaac tctattgatt
    13201 acaggtgcta cagtaacaga aactgccaga attattggag taaatagaaa aacaatctat
    13261 aattggatga ataaagagca tgttaggaaa gaaatggaca gacggaaaca ggagctaaca
    13321 aaccaaggaa atttaatgat attaaaggat ttagatagtt atatcaacaa tatcaaggaa
    13381 ttagctagtg acaagagcga taagagggtt atgttggcag ccaatcagta tcttataaat
    13441 cgtatatatg gaactcctac aagtacagtt atacaagcag aggataatag tgttggcatg
    13501 ggtatggatg caacagagat agaagcagct atagctaaga taagaataag aacaagcaag
    13561 aagtaattag atatgaaata aatcctgcaa gaatatgttt taattatgtt tgaaatcaat
    13621 taaagcaaaa catatattat atatatattt actttaataa ttaaatcata tattgtattt
    13681 aactttagtt atagctaatt taataaaatt tagtgagact taataattaa agtttcatac
    13741 agtgaagtga tgtggattat tataggatat gtgaacctat tggaaatgct aggttctttt
    13801 taactatgcc gaaaatacat atttaaggaa tagttgaaag ataattaata attctaatca
    13861 aaaaaatatt tcttgcaaga aaataattca aaatacttta atatatttat tttttttatt
    13921 aatagggggt gtccttctat tttgaaaaaa ttatttttta tggaaaatga gttctagaaa
    13981 ttttctagca aaatttaaaa accagagatg tatttcaaag agggtgattt tattagagaa
    14041 aaatttacat tgtttatttt attaattgca ttactcactg agcctaaaaa aatagaagaa
    14101 gtaagaggaa gtaaatacga gtggataatc tagaaagaaa tatacaatta atatttagtt
    14161 atctagcaaa gacttttata agaaatggag catctataaa agatgctgaa aaagaagcaa
    14221 atgagattat aaaagccaat tcaaacaatc tttggggagt taatggtctc gcttatcaac
    14281 ttggaaaaat aaacctagaa tttttctgta tgtattttat gcaagacaca tatttaccaa
    14341 aagaagataa tgctgctgct cctatagcta aagttcatca tgagctatgg gaagatatac
    14401 aagaatctat aattggagat ggttcacagc aattaggaag aatttatcca agagggacag
    14461 gtaaaagtgc atttggagat ttagcgacaa ctgtatggtc gcattgctat aaacataaga
    14521 catatacttt gatttgctct gacataggat ctacagcaga gaaatttgta aaagatataa
    14581 aaaatgcatt acttgaaaat gagtatatta aaaaagcatt tggtgtcctt ttaaatgata
    14641 atgatagaaa atacatttgt aatagtactc aactagagct aacaaataaa acttttattg
    14701 aagctatatc atcttcatca cccatgagag gaagaaaata caataataac cgtccagatc
    14761 ttatcatact tgatgattat cagtcagaag aaaatgttag aacagaagat gctagagaga
    14821 aaaaatttaa aagattttct gatgatgtaa aatatgctgc tcaaaaacca gtcataagaa
    14881 atggtaaaac tataaaaaga ggaacaactt ttatagcatt aggaacctta caacacaaag
    14941 aatgttttta tagtagacta aaaaatttac caacttggaa gtttaaatgc gaaaaaggag
    15001 ttttagttga taatgtagat gaattattta attctggttt atggcttaag ttcaaagaga
    15061 tcttatttga ttttaaaaat acaaatcatc ttgaagatgc taaagaattt tactgggaaa
    15121 atgaaaaaga aatgaaattc cctatattat ggccaagttt ttgggattgt ttagatatgg
    15181 ctctaagtta ttatgaaaat ccaacatctt ttaagcagga agtgcaaaat gatgtcaatt
    15241 ctataggaga aaaatggttt aaaactgtta gaacagaaac tagagaagaa attgaatcgc
    15301 atacttttaa aaagacaatg ctgttatgtg atccagcatc tgcgggtggg tcgaaacatg
    15361 actatagcgc ttttcttgtt ggaagtgaat cagaaaatgg tttactatat ggaagattgg
    15421 cagaactagc taaaataaat gctagaactg attttgataa atatatagac catatgattt
    15481 atttattaaa agtgtattca gatataacac atatttatat agaaaaaaat acatttaatg
    15541 gcgcagatgc caaccaatta gagtttaaaa taaaaaatga taatgttctt agttatagag
    15601 atatagaaat cattaatgag caacaaaaga aaaataaaga tgataaaatc tctactttaa
    15661 tacctgtttt aagcaaaggc caaatgattt ttgcagaaga agataaggaa tttatacagc
    15721 aaatacttga ttttacagga caaaaatact ctctacatga tgatgctccg gatatatcat
    15781 cggaatttat taatcgaatt aacaacataa aagtttctga gacagtaaat atctttgata
    15841 gaaaattatt aggtttttag ttgggaggta atttattggc taatagatca aagtttgaag
    15901 aagttcaaaa aactttaact aaaaaaggaa agaagttcaa tgttggaata ggaaaagatg
    15961 aaaaaggata ttttgcatat actcatagag caaggagtaa aagttatatt tcaaagcaag
    16021 atattccaat aaaagtttta aaatttatag agtctacagg ataggatgtg ttgttaatgg
    16081 aattagattt agacttaata aaagacatat atgacgattg gaactctaat aaatccgaat
    16141 atgatactat gtataagtat tataaaggtg aaacggatgc tattagcaac tataaaatgg
    16201 ttaccaagag atctaataat aagataaaca ctaatttctt aaaaaagttt attaatgaag
    16261 aagtcgctta ttctcttgca aataagatta cctatacaag tagatctggt gatgagaaga
    16321 ttataaatga tttagaatac tatacttgcc attggagtaa aaaacatgac tcagatttat
    16381 tgaggtatgc actattattt gggctttgct atgaacttta ctatgtaaaa gatgatgaaa
    16441 tacaagtaaa gataatcaag ccaacagatg gctgtcatta tgaaaatgaa aatggagaaa
    16501 tagtatgctt tattagagag tttaccaaag gtttcgaaga tgacacgtat gtagatgtat
    16561 atgacaaaga atatatatat cattttgatt caaatttcaa agaagttgaa agtcctacag
    16621 taaacaatat atttgatgga aatgttccaa tatcaatttg caaaagaagt gaagaactag
    16681 gaaaaaatac aatatttaat gatataaaag ggttacaaga tgcttatgaa actaatttaa
    16741 gtgatataag taatgaaatt agtgatttta gaaatgctta tttaaccttt tctggatgta
    16801 atattaaaga agatgatttg ccaaggatga aagaacttgg aatacttcaa gttaatggag
    16861 atggaaaaat agagtggctt attaaagata tgaatgatac atttgttcaa aatacactat
    16921 cttcaataaa agaaaatatg tatgaaatta catctcatat aaatcacaat gaaaaaatgc
    16981 aaagtaatac atcaagtcta gcagttatag caagattaat cagtacagaa tggatttgta
    17041 gccaaaataa tgatagtatt gcagatactt tatttaatag gtacaaatta ttgtgcattt
    17101 ggcttaataa aaaatatggt tttgactatg attataaaga tattaaggct aaatttaccc
    17161 ctaagatacc acgtgatgat ttagttgtag caaatatatt aagccaactt ggagataaat
    17221 tatctactga aactggctta tctcaactaa gtttcattga taatcctcat gctgaaatag
    17281 aaaaagctaa aaaagaacag gaaatagttt cagagggaga gattttatta gatgaatcaa
    17341 aagattataa ctaaattgac tgaagatata tataaatctg ctgaaaatag gacaaaacca
    17401 ttttataagt atcaaagaga aaatagggat aaacttttat tagaaatagc aaagatattg
    17461 ctaacacacg atattattaa tgaatactta aatattaata ataaagataa gaaaaatcta
    17521 aggtcaaaac ttaataaaat tataaatgag tattctaata gttatgatga agaagtcaag
    17581 gatatagaaa ctattttatc tgattcatct aagaataaat attcaaattt gataatttta
    17641 ttaggagtaa tactgaagat aaaagatgtt agtaatataa acaataaagt tataaataag
    17701 atagtgaata ataaggttga tggaaaacat tggagcgata gactctggaa gaataaaaaa
    17761 ggtatagaag agtccttaaa aaaagaaata aagagttttc taaatggaaa aacttctgta
    17821 aataagatag aaaaagcaat aagagataaa tattcaacag gtgcaggaca aaccagcaga
    17881 ctaatagaaa atgaagttgc cagatgtcaa agtgaagtaa atgagtattt tttcaaggtt
    17941 caagggatta taaaagtaat gtattgtgca gatttagatt ctcgcacatg tagtgattgt
    18001 tctatgcata atggagtgat attttatgtc aatgaagata ggccctcttt gccaagacac
    18061 tgtcactgta gatgtcaata tatacctgtt taacatgtat taattaattt aataggtgtt
    18121 tttattatgt ctaaaaaata tgaggtgaaa tatgaaagtt gaaatattag gaacagaata
    18181 tctagtgata gagaaacttg aaagcgaaga tgtgctatta aaggaaagag ctggatattg
    18241 tgatcactct gttaaggaaa ttgttataga gaaaataaat tctgaagaag gttcattgaa
    18301 agatttaagt gtatataaaa atgaagttgc taggcatgaa ataattcatg catttcttag
    18361 tgaaagtgga ttgaagagtt gtagttcttg ggctacaaac gaagaaatga ttgacttctt
    18421 tgcaattcaa tttcctaaaa tagtaaaggt tatggataaa atagaatgtt tgaattaaat
    18481 tttcaaaaag gagaacttta tacatgttaa aaaaagaagt gttggaatta ctaaaagaaa
    18541 tagaagatga tgcagaaata gattcattgc tgcaatcaac agatttattc aaatctgcat
    18601 ctgataaaaa gcttacaata gaagagttta gagaattaat taataatgat gcaaacttta
    18661 aagctattat agataatgaa aaaaataaat atcacagcga agcacttgaa aactttaaga
    18721 aaaaagatat gcagacactt ataagtgctg aagttctaaa aagaactgga gcaaatgaaa
    18781 cagaagagca aaaagcaata agggaattaa gagaaagcct agacaaacta aaaaaagaaa
    18841 agcagtacgc agaaaaagtt tctaaatata aagatatttt agttgaaaag aaaataccta
    18901 caaacttaat tgaatatcta ttatctgatg atgatgataa aacaaatgca aatatagaga
    18961 tatttgaaaa ttcaatgaag caatatgtgc agtcaaaggt agatgaaaga attaaagatg
    19021 gttcatacgt tccacctggc aaagatagtg caggttcgct atcagaaatt agaaaacaaa
    19081 taaagcaagg gctaaatagt ctttagtata aaaaaagaaa ggatgatttt ataaatggct
    19141 aatgtattac aatatgtaac actttttcaa caagaactag atatgcaggt aacagttggc
    19201 tcaactactg gatggatgga gaaaaatgct ggtcaagtta tatataatgg aggaagagag
    19261 gtaaaagtac caaaagtaac aatggatggc ttaggtgatt atgacagatc taaaggatat
    19321 acgcaaggcg cagttacact tgagtacgaa acaatgaaaa tggagatgga tagaggtagg
    19381 acttttatgt tagattcaat ggatgtaaat gaaagtaact tcgttataaa tgcatcttct
    19441 gtaatgggat tatttcaaaa gcaacatgtt ataccagaaa tagatgcata tagatactca
    19501 aagatatttt ctgaaacagc taaagtagat gagcgtgtaa aatattcata cgaagctaca
    19561 gtaactacaa tattaagtga attgaaaaat caacttgcat caatacaaga tttatctgga
    19621 gatatacctc ttattattag tatgtctagc ataattgcaa gcatattaga acaatcatct
    19681 caacttgatg atattgaatt tggcgatgga gatataaaaa gaattgtaaa gtctatagac
    19741 aatgtaccta taataaaagt tccatcaaaa agaatgaaaa cagaatacgt atttagagat
    19801 ggtaaaacat ctggacaaac agagggtggg tttactgaag gagcaaaggc tttagatata
    19861 aactggttaa taactccagc atctgctcca attgcagtat ctaagactga taagccaaga
    19921 atatttactc cagatcaaaa ccaaacagca gatgcttatc aaatagacta tagaaaatat
    19981 cacgatttgt ggatattgga tgaatattta aaactttgta gagcatctgt gagacaagct
    20041 aaagctgcac aagaataagg agttgtttta aatgtttgca ttgataaaaa ataacataat
    20101 taaagttgtt gaagatgaaa attcgagaga taaattgatt tcaaaaggat ttaaaatata
    20161 ttcagaagaa gtgactaaag agaatattga gaaaaaagaa gaaaaagtta aatcaacctc
    20221 taatgattta tttaatctat ctaaaccaga gcttatggaa attgctaaag gcaagaatat
    20281 aaagggatat tcaactaaaa ctaaagagga attaattcaa ctactagatg agtacaatgc
    20341 ttgataatgt taaattagtt ttaggaatag aaaatgatag atatgacaaa ttaataatcc
    20401 tttatataaa taaaataagt gagatggttt tagaatattg ttctaggcag gaactaagta
    20461 cagcactaga agggtttgta gaagaaaaag taatatcaat attatcttca agatttgaag
    20521 aacttaagaa aaatagtgga cttgataatc tagaaaaaag cttaaaagct ataactagag
    20581 gtgacactaa gatagaatat aatgctttaa cattacaaac tgctgaaaat agcatcagtt
    20641 catcatcttt tttaactgat actgataaaa aatttctaag cccattttgt attgttagta
    20701 tgtactaagg ggtgattaaa tgactgaagc agatatatta gaaatgacat accttgataa
    20761 aatgactata attagaaaat taaaaggctg gaatgaagaa acatgttcta atgattttag
    20821 taatgttgtt atagctgaaa atatcccatg tgcaatttct agaaaagaag aagccattgt
    20881 aaatggtgat attggatcta tagttgtaaa tagaaagtta ttttgtagac cagaagtaga
    20941 tataaaaata ggtgatacta taaatacaac ctataatcat ggagaagaag ctgtatttaa
    21001 ggtttctaag gcaaatatat atccaagcca tatggaaata cctattacag aattggagag
    21061 gatataatgg gaatagataa tttaggagtc tttgaagcat tagccttaga tttaggtcta
    21121 aatgcatcaa actttaatag aaaaatcaag aagtttacaa aagaaactgg gcaagaacta
    21181 gcagaaaata taagagatga aactcctgta aaaactgaaa agttaaaaaa gggatgggaa
    21241 gaaaagcaac cagaatatga tacttatatt gttaaaaatg aagttgatta tgctacttta
    21301 gtaaataatg gccattcaac taaaaatggt ggcattgtcc ctggttcttt tatggttgaa
    21361 aagggaattg aaagaacaaa agaaaatatg acaagtgcaa aagcaaattt atttgattgg
    21421 taggtgatta gttgcttaca aacagagaca ttataatagc agttaataaa agaatcgaaa
    21481 atgagtttag atatatagat atttttatta atgaggataa tatacaaggc tttgaggagg
    21541 cttgtttttt tgtgcaactt ttacctgttt ctaataatat tgcaaataaa gttttagata
    21601 ctaaaaagat attcatagat attgaatatt accaaaaggc tagaaaaaat aaattaaatc
    21661 tatacgacat acaaagtaga ttagaaaaaa tatttaacag aaacattaga gttaaagata
    21721 gaagtttaat cattgagaat atatctccat caatcgcaaa agatcctgta ggatataaac
    21781 taacttttct aatgactgta tcttattttg aagaagtcta ttttgaaaat gaaacatttg
    21841 aaattatgga aagtgtagat ttagagatag gaagtgatta aatgggttta ccagaaatta
    21901 atatttcttt tatccaagca ggaaaaactt ttgttaaacg ctctggtggt attgtagcgc
    21961 ttattttaaa agatacaaaa aatatagggt tagttgagat aaaagaaata gaggatattc
    22021 cagaaaatta ttctgctgct aatttagatt atataaaaat ggctatgaag ggaaatgtat
    22081 atcctccaaa taaagtatta gtttatacat tagatacaga tgaatcaata gatgatgcac
    22141 tagattttct tgaaacttgt gagtttaatt atctttgtat gccagatgag acagaacaag
    22201 atttgcctaa aatcaaaacg tggattaaga aaatgagaga agataataaa ataaaggtta
    22261 aagctattac tgcaagtaat tcagcggatt atgaaggtat aataaacttt acagcaactg
    22321 atattgaagt tgaaggtaaa aaatacactt caaatgaatt tctgccaaga atagcaggtt
    22381 ttattgcagg aactccatca actcaatctg taacatatgc agaaatacca gaagttacta
    22441 atatacctaa gctaacaaga gctgaagcaa atacaaggat aaataatgga gagctaattt
    22501 taataaaaga aagtggagct atagtaatcg ctagaggagt tacatccttt acaacaatta
    22561 ctgattcaaa aggtgatata ttcaaaaaga ttaagttggt tgatacacta gatcaaattc
    22621 ataacgatat taaaaaaata attgtaaaaa attatatagg aaaaacccaa aacacttatg
    22681 ataataagtg tttacttatt gttgcaatac aattatatct tcaagaatta gaaaaagatg
    22741 gtttaattga tgaaggttca actgtagaaa ttaatttaga tgctcaaaga gcatggctaa
    22801 aaaaacaaaa tatagatata tctaatatgg aagaacaaca gataaaagaa tacaatactg
    22861 acactcttgt atttttaaaa gcaagaatta aattaataga tgcaatggaa gatgtatatt
    22921 tagacatctc tatgtagttt ggaggttaaa atttgaaagc taaaatagat gcaaaaagaa
    22981 taatatctgg tacttttgga gagtgttggc tagataataa gcaacttaca tcaacaaaag
    23041 ggatggaggc caaggttgat atagataaag aagaaataaa attatgtggt caaataatga
    23101 ccacatataa aatgattggt gcaactggaa aaggatctat aactctttat aagataagta
    23161 ccttatttgg cgagtatgtc gaaaaaatgt taaatgaagg taaagaattt aaagtaacta
    23221 taataagtaa attgcaagac ccagattcat atggttctga gagaattgca ctttatggat
    23281 gtatgtttga cgacttaact ttggctgatt gggaagctgc gaaagttgga gaaatagaag
    23341 ttccattcac atttgaaggc tttgaatact tagataaaat aaaagaaaaa taggaggatt
    23401 ttattatatg aacacagtag aaaaattatt aaatatggat gcaggtaaat taaaaatgcc
    23461 atctagcgca tttgaattat attgtaaaaa actagatgat actttagaaa tagagtgcaa
    23521 ggctattgat ccagaacgtt ttgacgaaat aagaatgaac tctatggacg ttaatagtgg
    23581 agatgtagaa aacattaaca tatatgaact taaagtaaat acaatattag aatcatgttc
    23641 tatatttagc aatatggaat tagttaaaaa atttagtgca attacaccta aagaattaat
    23701 taaaaagcta ttacttagtg gtgaaataga taaattatac gaggaggtta ataaagtaaa
    23761 tggaatagat gcagagggag ataaaaaaag acaaaaagaa agagctaaag atataaaaaa
    23821 ctaattaaaa cggatggaga agttaacttg atgtacttat tatttaagta taaaggtata
    23881 atgccatccg tttcttatca tatactaaga ggcgaaaaag aaattgttag tgtttttatg
    23941 gatcaagaat tagatgaaag aaaagaagaa ataaaatctg gtgttgggag gttgttttag
    24001 tatatgagtt ctaatacaaa ggtcctacaa gcaataataa aaatgagaga tgaagcaagt
    24061 tcaacattaa aaagagtagc agcaaatact agagctctac atgattcatc ttcccaagca
    24121 tcaagagcat taaataatgt tcaaagtaat ttaaaaagtg ttggaactag tgctttaaaa
    24181 gcaggaggtc ttatcactgc tggagttggt ggtgcatttg cagctgcaac taaagttgga
    24241 acagaatttg aaagcgctat gtcgcaagtt aaggctacat ttggaaattc cttaaaacca
    24301 ggagattttg aagctctgtc taaggctgct agagatgctg gaaaagctac aactaaaact
    24361 gctgctgatt ctgctaatgc acttcagtat atggggcttg ctggatggga tgttcaaaag
    24421 tcaatgcatg ccttaatgcc agtgcttaat ttatcagaag cagcctctat ggatcttggt
    24481 ctagcatcag atttagtaac tgatagcatg agttccatgt gcttagaagt tgataaggtc
    24541 agtaaaagtg gaaaagtact agctggtgca ggtttaagtg agtatttaga taaagttgca
    24601 aatgcatcta ctaaatcaaa tacaagtata caacagttga tggaagcgtt taatgtcgca
    24661 ggtggtacat ttagcaattt aaaagttcca ctttcagaag caactgctat catgggaata
    24721 cttgcaaata gaggagttaa gggtacagat gcagggcatg ctttaaactc tatcatggta
    24781 aatcttacaa caggtgcagg tcaagcaggt aaggcaatga aaaagttagg tgtaagtgca
    24841 tttgataatc aaggtaaatt taaaggtatg tcaaatgtgc ttaaagaggt tgcaaataaa
    24901 actaaaggta tgactgatga acagaaaaat tattacttat ctgctattgg tggaaagact
    24961 caattaaaaa cgttacaaaa gttacttgat ggtgtgggaa atgaatatga tagcttaaag
    25021 aaaaaaatag ataattcaaa aggtgcttta aaaacaatgt ctgatgtaat gaaggataat
    25081 actaagggtg gacttgcaac cttaaaatca gcccttgaag aaactggaat tactatttac
    25141 tatcaactaa agccagcaat agcatctgta gttgataatt taactaaaat gactgtttgg
    25201 tttaataatc taagtgaacc aataaaaaga gtcataacta atgtaatgct ttcagttgga
    25261 gcatttggag tacttttatt aactataggg gctgtgtctt taattgtttc aaaagctata
    25321 ggtatatttg gcttttttgt tccaataata ttaagagcaa aagttgcttt cagagctttt
    25381 gtaattggta tgaaaccatt aagtgcagta tttttagctg taatgggtcc tgtgggatgg
    25441 actataacag ctgtaattgc attatcagta gcatttacca ttgcttatgc taaatctgaa
    25501 gtatttagaa ataaggttaa ttcattagta aaatcattta cagaatttgc aaagcctata
    25561 gtaaattttt gtatgcctgc acttaaacag ctaggagaga aatttaaaga gttgttatca
    25621 gcatttggtc cactatttgc atctatttta aacctaggaa gtgtaataat gaaggtacta
    25681 ggacctgttt taatcggcgt aataggtttt catatagcaa aattagtttt gattttatct
    25741 actctggcaa ctgcttttaa agctgtagtt gatactataa ctaatgtatt aaatggtcta
    25801 gcatctattt taaatggagt atttgattta attataggta ttgtcacagg cgatagtaaa
    25861 aagatgatgg atggagttaa acaaatattt gatggtggaa ctaaaattat aaaatcaatt
    25921 tggaaaggtt tcatagattt tgtaactgct cctatacaag ctatagctga tatagctgac
    25981 agcttattta aagataaagc taaatggctt acagataagt ggagagattt aagaacattc
    26041 ttagaaaatc caattgaagc aactgccaaa atatctacta aaacaaatgt aaatatccca
    26101 ggaagtaaag cagcagatgc agctggtaaa tctacaccaa atacaggtgg attaaaacaa
    26161 acagtagcaa atctaaaagg ttcatttagt gattttaaaa cttttattaa gcctatgaca
    26221 gactctataa gtcaaggagt tgaatctgga aaaactaaat ttacagaact gcaaaataaa
    26281 atattaaatg atgttaaacc tgcactaaag gtcctagagg attctggagt aaattttaag
    26341 gataagttta aggagtcaat aacttcaata aaagataaat ttaatgaatt aaagaacata
    26401 ttagctggaa atattaaaac aaatatagat aatttagtaa aagcatttga acctttaaaa
    26461 cctcatttag ataatttgaa agattgcttt gataaggtta aaaaagcgat tactgatttt
    26521 tttactccag ccaaacaggt tggagataca gtaaacaaag taagccaacc aatggatagt
    26581 gttaaaaagt ctactgatgg aattaaactt tctttccaaa gtttaactca agcacttgct
    26641 cctgttaaag cttggtttca aggatttatg cctttcctat cacaaatagg acaacaactt
    26701 ttaccatcta taggaattgc aatagctggt gttgttggcg gaataatttt agcatttaca
    26761 tgggttttaa atacattgac cgcaataata acaacagtat ctggaatcat aaatggaatt
    26821 atgtctttta tatctggaat tattaatgtt attatggggc ttataacagg aaatgctgat
    26881 caaactatgg atggacttaa acaaatattt gatagtggag taggtgtaat aaaatcaatt
    26941 tggaatggcc ttgttgatct agttagtggc gtactagaac ctgtaataga tcttgctgat
    27001 tctcttttca aagataaagt taaaggggta aaagaagctt ggaataaact taaagatttc
    27061 tttaaacatc caattaaggg aacaatagaa atatttaaaa aaggtcctag tttacaaatt
    27121 ggaaaaggtg cagatgctgc tggcaaaagt ccaagaaaag catttggtat aaatagagtt
    27181 cctagaaatg attatttaat aagagcacac gaaggcgaga aacttttaac caaacaagaa
    27241 gctaatcaat acaaaaggaa tagttcaaat ggaagtttat ttcttgataa attggctgat
    27301 acaataattg taagagaaga ggctgacata gataaaattg taagaaaaat aaacaaaaaa
    27361 atatctcttg caaaaattgg aggtgttttg taaattatcg tgctataatt gtagtatata
    27421 atttacaggg ggttatgtta tgaataaaaa aatactagta ttaacaatat caattatact
    27481 atctttaagt ttagttggat gcagcacaaa taattcaaaa aatagagata gtaaatctaa
    27541 gcaaaacaca gaggaagtta aaaatcataa aataggcgaa gttgttgatt tagatggagc
    27601 aaaagtatct gttaaaaata ttaggaaatt agaaacaaat agtaatgatt atgctgttga
    27661 aattgaaata actaatacag gtgataatga tttacaaagt gattatctag aaaactatat
    27721 attaaaatca agtgacaata ctactggaga agcaataaat aaccaagaat taaatggaga
    27781 gttaatgttt gatacaatac gcccaggaga tactttgaaa ggtgaaatag cattcgaact
    27841 tacaaaagat gcaacaccaa aaacacttga aattgcttat gaaaatgtag gcaaatatac
    27901 agtatttgat ttatagtaat tatcttaaaa gacgcttatt tacttaagtg tcttttattt
    27961 taggaggagt ttaatggaaa tatggttaag acaagcaaat aatacattta ggtttcctgt
    28021 tattccaccc tcttttgaga taaatggaag tgcgacaata aatacatcta atattttaag
    28081 tgttggagat atcgcagtat ttggaggatt agggcttaaa actatagaac tatcctcttt
    28141 tttccctaat caagaatata gtttctgtaa ttataatgga tttccaaaac catatgattg
    28201 tgtaaattta atagaaagtt ggatgaaaga aggatatata ttaagattta tcattacgga
    28261 aactaatata aactttgaat gtataattgc agattttaat tatagagaac aagattattc
    28321 aagagatatt tattttacct taagtctaaa agaatacaga aggatacaaa tatccaaagt
    28381 aaacattaat aatgatgaaa aattatcttc tgaaaagaat gttcctctaa caaaaggatt
    28441 tgatactaag caaaaaacgc ataaggttgt tgaaggagat actcttttta agatagctaa
    28501 aaaatattat agcaatggag atttatggga gaagatttat aaagcaaatg aagatgagat
    28561 taaagatcca tctgtaataa aaaatggttg ggtattaata attccttaaa aatggtggtg
    28621 atttataatt aataaaatca aaatacaagt tcatataaaa aacggaaata tatataatgt
    28681 aactgattta gtggataaat gcacttggtc tggtgattat agatcaccat caagaacttt
    28741 ggaattttct ataattcaat ctgcaagtga tattaatttt aggcagatag atattccagt
    28801 agcaagtaca gtttgtttct atgtagatga taaagaactt tttagaggaa tgataataga
    28861 tagatctaaa gactctagca ataataatat agattttaca gctaaagata tgggtttttt
    28921 acttttacaa agcgaagtgt catacaattt taaagataaa ttagtcgaag atattgcaaa
    28981 acaggttttt gtagataata aattcccact aggtaattta cctaaaacta acgttaaata
    29041 tacaaaaatg tttattggtg taactggcta cgatactata atgagcgttt atacagaagc
    29101 aagcaagaca actaaaaaaa agtatatgat agagtctaat cttgataaat ttaatgttat
    29161 tgagaagggt gtagttactt taaatataac atttgaagaa ggctttaatc ttatcaatac
    29221 aaatttttct gaaagcattg agaatgtaaa aaataaagta ctagttgttg atcagtatgg
    29281 taataaaatt agtgagaaaa taaatgactc tatatttaaa gacgttgggg taattatgca
    29341 aaaggtaata caacaacaag aaaacagtac tatagacata gatggagagt ttaaaggaat
    29401 cgaaaaaact tgctctttaa aaggatatgg tgatataact tgtgtaactg gtagaggtgt
    29461 aaaagtaaaa gactcatata caaaattaat aggtcttttt tatatagata cagataagca
    29521 tacatggcaa aatggagatt atcaaattga actagagctt aattttgaga atataatgga
    29581 tgaaaaatct gctggccaag atgagcaaaa agaagatggt tcagagtata ctggaggaac
    29641 agaataccct gctgaattta cggcttattg tcctagaaaa gaagagggtg gaaatacaga
    29701 ttgtagaggt aaaaaactag atccttctaa aaagacatgt gccgctccta tggttggagc
    29761 atatgaaaaa tcttactata caaaagattt cttaaacaaa catcctctta tgagatatgg
    29821 agatgaaata caattagtta caggtgtttc aagccgagat ggaacgtata aagtaaatga
    29881 taatgggcct gcaataatta tagaaaagga tggaacatat catatagata ttttatttgg
    29941 aaatgttgaa gaagctaata actttggaag aagaaaagga aagattataa ttggtggtta
    30001 ttctggaaac atgacagaaa aagcaaaaac agtaatttca gaagcaagaa aacatcttgg
    30061 aaagccatac aaatggggtg ggaatggacc aagtagcttt gattgttctg gactaatggt
    30121 atattgcttt aagaaggtta atgttaattt accaagaacc tcaagtcagc aatctaaggt
    30181 aggtaagaaa gtagagaaaa ataatttaca ggcaggagat ttggtatttt tccataatcc
    30241 agtcagccat gttggactat atgtaggtaa tggagaattt ttacatgcgc cacaaacagg
    30301 agatgtagtt aaaataagta aattaagtaa tagaaaagat tttaatacag ctagaagagt
    30361 tttgtaaaag aggtgatatc gtggcagatc caatcaatga atttatagga ataattaggc
    30421 aagaaggtaa atttcataat gaaccttctt tttttattgg aaaaattaaa agtaaattac
    30481 cagatttaaa aatagagata aataacatca tattagaaaa agaagatatt ttgatagata
    30541 gttggatgct tgatagacag atagagttat ttgatacaga aacaagtcaa gaacataaac
    30601 atgaaataaa aaatcccttt atagatactt ttgaatctgg aaacacagta ataatgttta
    30661 aaataggtga aaaatttgct gttgtaagta aattggtgag tctagatgaa taatactata
    30721 ttccctttca tgggtgttcc agaagattat atttctccag acaatgaaga attacctatt
    30781 tttaaagaat ttgcttggga ttttaataaa gatgaaaaga taattgaaaa tggagacttt
    30841 aaaatagttg aaagaaatga agcaattaaa gtatggattt acaaaacaat aaaaacagat
    30901 aagtatgttc atttaatata tgattggagt tatggaacag atataaaaaa tctaataggg
    30961 caaaagtata ctaaaggtct tactgaaagt gaggcaaaaa ggtatataca agaagctcta
    31021 ttaactaatc catatatatt agaagtcaat ataacaaatg cagaatttga agatgataat
    31081 ttatctataa gtttaaatgt aaaaacaatt tatggagagg aggagattac ttttgtataa
    31141 tggccaatca ttcagtacct taaataatag aactttaaat aacataaatc tccctcttta
    31201 taaaggccaa ggatcttctc tttataatat agtttctcca ataaattcag aacttgcaca
    31261 attatatata gaactttctt atatacataa gagagttttt attcaagata attttgacga
    31321 ttttcttgat agaagagtca atgaatttgg cgtatataga aaattaggta cagaggcaat
    31381 aggtgaggta acatttgagg gcaaaattgg aactcaaata ccaaatggaa caataatatc
    31441 tcatagtgat ttactatttg taattattaa agatattaca atagatgaaa atagtaaatt
    31501 aaatgtaagc cctatacagg ctttagagat tggcattaag tataatttat cagctaacac
    31561 agaatttaaa cttatagaag aaataactgg agtaactaaa atttataatg aacttgacct
    31621 aaagggtgga acagaaatag aaactgatga agaattaaaa gaaaggttct ataaaataca
    31681 aaaaaatcaa gcgacaagtg gaaataaggc gcattaccaa tcttgggctt tagaggttga
    31741 aggtgtttat aatgcaaaag taattcctcg ttgggatggt ccaggtacaa ttaaaattct
    31801 aatttatggt caaaacaatc aatcagttga caatgaagta ttgcaaagat gtactgaaca
    31861 tatagaagaa gaaaaaccta ttggacctac tgttacaatt gttacaccaa gtacttttga
    31921 tattaatatt agtgcaactt taacacttga aaatggatat gatattgaat ctataaaagt
    31981 tgtgttttta gatattataa attcttattt gatagaaaat tcaagagaga ttgtttatat
    32041 aaaagtaatg agtttgttag caagcataga aggtattcat gatataaaaa atctccttgt
    32101 aaatggtgat gttaaaaaca taatagttga tgaagaaaaa gttcctgctg tttcaagtgc
    32161 tatatttgat atcgaggtga gttaaattga agttaattga ttacctgcca agttttgcaa
    32221 acaatgaaat tgacatacaa atccaagaag cacttgaaaa tgaactttta acgctaattg
    32281 atgaaaaaga tgatttatta gaacagtttt ttatagatac agcaacttgg ggacttgatg
    32341 attgggagaa ccttttaagc ataaaagtaa attataagtt agacttcgat actagaagaa
    32401 gcaatataaa agcaaagatg agaggtaagg gtacaacaac aatagaggtt ataaaagcta
    32461 tctcggaagc ttacacaaag accaatgttg atgtagaagt atttagtaat ctatttagtt
    32521 ttacacttag ttttataaca aataattgta gttataacac tattttagaa ttagataaga
    32581 aaatagaaga aataaaacct gcacaccttg aacacaaatt cgagaggata ttatttaata
    32641 aaaacgagct ttatacaggt gcagcaatta gtacaggaga aacagttaca atatatcctt
    32701 atgtacctag aaatttagaa agttttggag aaatagctat ttgtagtgga aatgatagag
    32761 cattagaaaa agtaacattg tatcctaaaa aatagaaatg aggtgataaa attgacagaa
    32821 caacaatatt ttactctagt aactgacatt ggtaaggcag caatagcaaa tgcaagtatt
    32881 acaggtgaaa aagtagattt tgcaaagata aaagttggag atggaggagg gagttcttat
    32941 actccaaatg agagtcagac agcactaaaa aatgtggttt gggaaagtac acttgaacat
    33001 gcacaaggag ataaagataa tcctaactgg gtagtaatac aaaaattcat acctggtgat
    33061 gttggaggat ttgaaataag agaagttggt ctatttgatt ctaaagacca attattagcg
    33121 atttctagtt acccaacaac atataaacct actgcggatt cagggactgt aaaagaacta
    33181 ttaataaaag taatattagt tgtatctaat gtagctaata ttaatttgaa agtagaccca
    33241 accgtaattt tagcaacttt aaaagatata caagaattag acactaaaat agatacaact
    33301 aaaacagaat taacaagcaa catagaaact gctaaaacag agttgaacac taaaatagga
    33361 gatacaacac aacttactac aacagataaa acaaatatcg ttagtgcatt aaatgaggta
    33421 aaaactagtg tagatagtat agaaacaaca gcagataaaa caagtataaa agatacagat
    33481 aatttatttg agagcgacaa cgtagaggga gcattaaaag aagtgatgca agaagtaaaa
    33541 ggtaatagaa gcagtattat atcaacaata aatagtaatt taataccaat gtagaaagtg
    33601 aggtgataaa gtgaagatat ggaaatacaa tagaactgtg aagaaaagaa gaggtgtcta
    33661 tacagaatta gatatacttg cacaaaggta tgaatttgaa gcagatggga aactttatac
    33721 agcttatttt catttatata ctaataagaa tatagatata ttcagagata aagatttata
    33781 taaagaatct tatatgatga gctatagagt tggaaatgta acaactgata ttgatgatgt
    33841 agtacagcaa acaactacag taagatttat acctgaccct gttattgata ttgtgattga
    33901 taacattagc agaggatgtg aaataaacta cagaattata gataatgaac caagtgtaaa
    33961 attcattgtt acagaaaagt taaatggcac aataatagaa acaaagacaa attctagtga
    34021 taataattat aaacttaaat taactgatga acaaatagta ccattagcat tcaattccca
    34081 aaattcaata gtaatagaaa taagtacaga agatggtgga ttagtaacaa gtaaaacagt
    34141 aacatttaca agaacaaata acaagccaac aattttagtt aattcatata gttctaattc
    34201 tgcaaaattt acagcatctg atttagataa taatttaagt aaaattgagt ggtatttaga
    34261 tgatgtatta aaagaaacaa taacaacaga tttaacagca gaaaaaacca tcaactatga
    34321 atttacagac aatgcaatac acacattaaa aatagttgct acagatgcag aaaatgcaac
    34381 agttgagaag gttttaagta taagtaaaga gataatgcca cttcaatctg atgctagttt
    34441 aagtgatata tcaactaagc tgatagagat tggagaaggg tttagaaatg gtaaaacaag
    34501 tattataaac actttagcac ttaaaaatat agaagcaagt ttaaataata cacttgtgga
    34561 gttatcagag aaaataaaaa caagttttga tagttcagac gctagtgtgc aggatttgca
    34621 aaatagaata acagaattga ataatcagct tagtcgaaga aaaaaatggg ctacaggtag
    34681 atacacattt actagagaag aagatactat caatttcaga atggttgatg gagatagtct
    34741 ttccgcagta aaaaaactaa ttatacccat taatttagat tttgttccaa gtgttattat
    34801 aatagacaaa atgtttttag gtagttacgt acctgcacaa gatgtgcaat ttaattgtgt
    34861 ttcaaactta gccgatttta cacttggacg tcgtttctat aataaacaat ggatttgcac
    34921 ttcttctata aaactagatt cagttacaca aaatagtttt actctttctt tacaaaaagt
    34981 tgttccattt gataaagtta gtagtacgat tttttctatt attaatactg gttttgcttg
    35041 gagagcatat gaataaaaat ataaattaga ggtgattaaa tgaatagaaa taatagaata
    35101 atttacgacc aaacaggcaa gatatggctt caaactggtg aagcaatagg agatatacaa
    35161 gagttgtcag aaataactga attaaatttc atagatgttg aatttggtag tatagactat
    35221 agtaaacaat atatagagtc tataaatcca gttacaaaag aattaaatat aaaaaatata
    35281 gaagttgttt tgactgatga acaaaagaga ttagaagtat tagaaaaaga actaaatatg
    35341 ttaaaagaag aaaataaaaa tagagattct gagatagtaa atacagcatt tgaagtagga
    35401 aatatcaaat taaacaataa tttataggag gaaattatat gtataactta ttaaagttaa
    35461 tgatagaaca aaaaaactat agcactaagg aggatttaca acataagatg gatgtattct
    35521 atgcagtaaa taggattaca gaagaacaat atttagagtt aacaggttta ttaaataaag
    35581 aagaaacacc agtagaacca acaatatagg ttctttttta ttgaaagaag gtgactaaat
    35641 gacttttaaa gaattagtta gtaaagttag aaatcttgta ttagaagcaa agaatgtaac
    35701 tatagaagat acagagaata aattcactag tgaaaatgtc gagggagcat tgaaagagtg
    35761 tatagataga gcagatttgg cttttcaaag tgccgatagt ggaaaagagt taattgcaac
    35821 tgctatcggc tctcctgcta catccgaaca aacatttcaa gagtatgcta attatattgc
    35881 aggatttaaa aatactataa gtcagttaaa ttctaaatat aaatatacta gtggaacttt
    35941 tacctattat actggtgcat atcctaatgg gctaaatata ggttttagac cagatattat
    36001 ttcctatact gccattaatg ctgtagagga aaaatattat tgtgtataca cacctttatt
    36061 ctatcttttt tataattata caactggaga aaaatatctt gatgttaatc ataatcgtta
    36121 tggaataact tttactgaca atggatggat acctagaaat ccagttaaca atggtgtgta
    36181 tagttatata gcagctaagt gccgttagtt gtcaaagact tagataaatt tctaagtctt
    36241 attttaatac aaaattagga ggaagtatga acgtaacaat agttttttta gcaacaaata
    36301 tatttataaa attagtaata ttagcaatag catttgatac attgctaggt tgtctaagag
    36361 caataaaaac acatcagttt aatagctctt ttggaataaa tggaggaata agaaaagttg
    36421 caatgatagc atgtatattt tttctagcag tagttgacat acttacaaag tttaactttt
    36481 tatttatgtt gccacaagat tgggttgatt tcttacgact aaatcatcta ggaatatctg
    36541 aatttttctc tattttattc attctatatg aaagtgtaag tatattaaaa aatatgtatt
    36601 tatgtggatt accagttcct aaacgattaa aagagaaaat aggtagttta ttagatacta
    36661 tgacagatga attaaatgtt aaaggaggaa aataaataat gaaaatatgt attacagtag
    36721 gacacagtat tttaaaaagt ggagcatgta cttctgctga tggagtagtt aacgagtatc
    36781 aatacaataa atctcttgca ccagtattag cagatatatt tagaaaagaa gggcataagg
    36841 tagatgtaat aatatgccca gaaaagcagt ttaaaactaa gagtgaggaa aagtcttata
    36901 aaatacctag agttaatgct ggaggatatg acttactcat agaactacat ttaaatgcaa
    36961 gtgataggca aggaaaaggc tcagaggttc tatattacag taataaaggt ctagagtatg
    37021 caactagaat atgtaagaaa ctaggtacag tatttaaaaa tagaggagct aaattagata
    37081 aaagtttata tattttaaac agttctaaac ccactgcaat actaattgaa agtttctttt
    37141 gtgataacaa ggaggattat gagaaggcta agaaacttgg atatgaaggt atggctaagt
    37201 taattgtaga aggtgtatta aataagagta ttgaaagtaa tgaggtgaag caaatgtata
    37261 aacacacaat agtgtacagt ggtgatgata gagtatcagc agatatttta ggattatatt
    37321 ataagagagc aaaagaaagt tatctagtta tagatataaa agactataaa ccacatagaa
    37381 cacaaaatct atatgtaatt ggtggagtaa cttgtaataa aatgaaagaa atgagtaaga
    37441 ctacaggaga aaaatttact caactatatg gtaatgatgt atggtcaaca atggataaag
    37501 ttatagaatt tgtaaaagaa aaattataaa ttaaaagaca acctttaaaa attaattgtt
    37561 aataaaacta ataaaatttt caactcagaa ggagcattat atgttaacat ttttagattt
    37621 gtttgctggc attggaggtt ttaggctagc aatggaaaga gcaggacaca aatgcgtagg
    37681 ccattgcgaa tacgataaat ttgcaaactt aagttacaaa gcaatgcata acccaaagga
    37741 ggatgaatgg tttgaaaaag acattagaga aattagagca gaaaatattc ccaaagcaga
    37801 tgtgtggtgt tttggattcc catgtcaaga cattagcatt gcagggaaca aacttggatt
    37861 caaaggaaat cgttcaagtt tatttttctc agttacaaaa cttattagag aacttaaaga
    37921 agaagataga cccaagtact tacttattga gaacgttaaa aatctactta gtgttaatag
    37981 aggatttgac ttcgccaaac ttctcattga gttggatgaa atcggctaca atgcagaatg
    38041 gcaaaatctc aattctaaaa acttcagagt tccccaaaac agagacagaa tatacattgt
    38101 tggacatctt agaagaagaa gtacaagaga agtatttcct atcacaggaa cgagtagaaa
    38161 aactactctt gagcaattaa ataatcctaa tcacagttca aacaggattt ataattcaaa
    38221 tggattatca aagtgtttat taagtaaagg tgggaacaat acaggtcttt atagagttgg
    38281 caatatcaat cctagtggaa atggtgcagg cggacaagtg tatagtagcg aaggcttttc
    38341 tcccacactt acaactggaa aaggtgaaag cccaaagata ttaattaaag agaatactaa
    38401 aaaaggatac atcaaagcat ctataggaga tgggataaga ctagatcata tagaaggtaa
    38461 aactggccgt ggaagagttc agcacaaaaa aagttgtact ttgactactg caagtaatgc
    38521 tggcgtaatt ggtaaaaaat ttagagtaag gaggttgact ccaaaagaat gttttaggtt
    38581 acaaggattt ccagacgatt attacgatag agcggcaagt gtctgttcag aaactcaact
    38641 atacaagcaa gcaggcaata gtgttactgt agatgttgtt gaagaaatag caaagaaatt
    38701 aaaatagaat attaatacaa tgcaaaatgt ggtaggtttt tccttccgca ttttgcattg
    38761 cattagcttt tttggaataa cttacctgta ctatcttaaa taaaaaaatg ctactatatt
    38821 ataaacattt acaaggagtg cataatgtta atacaaagct taaaacgtgg cgaattaatt
    38881 gtaatgaaaa tcttttagaa aagaaattca agaatatcaa agaaagaaat tattcgcatt
    38941 tgcaatgaaa aacacaattg gcggaaatct gcgacaaaaa ctctacttaa aagacttgtt
    39001 aaaaaaagag ttctacttaa gagaattaaa attttccaca tatattacat acctatagtt
    39061 acagaaaaag aatatttcaa atataaaata aatgatttag agccagatta tttagatgaa
    39121 tattttatac gattaatgtc cactgtacat aaatttaaaa atctagatga agaagattaa
    39181 atatctccct tcatctactc ttcacatatt ttaatagact ttcaagcaat aattgactta
    39241 acaaatcatg cttatcataa tgtttattct catctgcaaa tttattaaac atttcccaca
    39301 ctgtattatt tattctaact gtagttcttt ttatagattg atctggaaga tctatagata
    39361 tatcattttc tttaatgaca catatatgat aactatcatc tttagtttta aaccattcca
    39421 gcacattctt tatattatca atttcactag ataaatattt aatatcgtca tcaatcttac
    39481 tgctaatgct atctatatga tatttatcat cataactttt attatcttct acaaacttgt
    39541 ttccagttct tttatatcct ttcttattaa gccacttcct tatagtactt tcatttgccc
    39601 ctaattcatc tccaactttt ttaagacttt caaattcact taatttatta ttaatacaat
    39661 caacaacttc attaatattt ttttctttca aatcactcca agtcatataa atcctcctca
    39721 aaaaaataat agattacaaa tatcatatat ttgtaatcta ttatacatac tataaactaa
    39781 atcctttttt atttcatcat ttttttgtat ccttttgcat ttgcaaaaac atgtttatct
    39841 acatcactca taactattat gccaggtata ttctttttaa atgcttcacc taacaattta
    39901 gcgcctccac ccataacaac aaccgcagct gtactaactg gataatttaa tttcaattca
    39961 ttgtatattt ctttaaatag agaaatagat gcatctatat ttttctttat atcttgtttt
    40021 tcaccattta ggtaaaatcc tttatttatg tagtcttgta ttttttctct ttttatctca
    40081 actttaccta aaaatctttc gtccatctca agagatttct ttattgcatc atatatattt
    40141 attgttccca catttataga atatggatca gtcgctttat tcccttgtac aagcgcaata
    40201 tctgttgtct ttccaccaat atcaactaaa acaacatctc ttcctgcaat ttggtcaact
    40261 atgtcttttg cataatataa gtatcctgta acaccttctg gaaatgtttg aatagatctt
    40321 attgttatat ctcttttagt agtctcattt cctcttgtaa actcaacatg atattctttt
    40381 ccttgtaatt tttcaataag attttttctt aatccggcaa attgtttcac tggcagacct
    40441 agccctagat caacaatttc atcatctgta tttctacata tagcccctaa tagtagtggt
    40501 aagaagtttt ctttctcata tttaactata tttatttcct cgtcaccttc acctaggtaa
    40561 tatgttttat tgcctatttt aatgctatct gaatctgaac caaagttttt tacctctgta
    40621 actttacttt caaaaatatc atctgtactt gttttaactg cataatttcc aatatctata
    40681 cctaatttac tcatttatgt tatttccccc ttattattct aaacttccaa aatcaaaatt
    40741 gttagctgga tcttctattt cttttttctg ttcaactaca gcattatcct ttttttcttg
    40801 cattttttcc caaacaagct cttttaagta agctgtagct gataatttct catctaaaaa
    40861 cttttcaatt gctttttctt tatcattgtt tttaaatgtt agaactatcc tactcattca
    40921 accacttcct tttttataaa atattataaa atttattaat atttatatat attttactaa
    40981 attttacaca gtaattcaat agatttataa gatatttttt ataatatttt ataatttttt
    41041 acgtaatttt ataatttttt ataaaattta tcattttgta tataattaaa aacacacttt
    41101 ttataatttt gcataaaaaa agagtgtttc atatatttct aaacactctt ttctactttt
    41161 tataattatc taattgtaaa agaagcttca gctggactag agaataatat aatacctcct
    41221 gtacacacac cttttccttt aaatttagca atatatgaac ccttttttag ccctttaaaa
    41281 gttactacac cagttttagt agttccagct aatctaaagc ctacatactg agatgataca
    41341 attttgccag ccttatatac atctatattt ccttcaaatc ctaaaatatt tccaagcgta
    41401 gatgttactc tccaagataa ctgcccacca ctcattgcag ttaaattagc agtaccacct
    41461 ggaacaacaa cagatttagt cgaaggcgaa tctgagtttg gttggccaat taattcaact
    41521 gtttgtgaat ttccagtacc ttcataatca tttccatcag caaaagctgt aaatggaatc
    41581 attactgcgc aaagcgttag taataaagca attgtttttt tcatttgttt tccccctatt
    41641 tttttatatt attctcaatt acagtttcct ttctttacgt gccttaataa tcatattgta
    41701 attatgctca gcagtttcaa atgctcctac caaaggagtt ataattacac tttctattaa
    41761 gcacaattca tcatagttta aactagcttc tccagcatag aaattattta acttatctaa
    41821 atctattcta gttaaaacgg aaactgattc cattgagaat ttgtaaacat caataagttt
    41881 atataatcca cctatatagt tttttgctac ttcatggctc ttaaaaaatt catcttttcc
    41941 tgtatgtagg tttacttcca taattccctc cattgttctt atatttttaa ccttcaaata
    42001 atatttactt cttcttcaaa acagaatatt ctatcacggt agaatattct gtttttttca
    42061 ttctatcatg atagaataat attttcaatc attttttcta ttctatttta tttaaataga
    42121 atagaaaaaa agaacactta atatttttca agctaatata ttaagtgttc tttttatatt
    42181 tttacaagat tatataaaat tattctttaa tcaattaaag tgtttttcta tttcttaata
    42241 ataagaaatg atataaaatt gtatcatttt aaagattttg tgatataata aaagcaagaa
    42301 gaactacaat ctatttaggc gtagagtgga gttcataata aacgtagttt attttttgaa
    42361 tttaaatata aatttaaatt caacctgtaa gtcactcttt gcacgagagt ggctttttgc
    42421 ttttttgaat agttcactga ttaagtaaac taccacacta gctgttaaac tagctaaaac
    42481 attaaacaaa aagttatcca tgtaactcac ctcccctcga atcgttggga ggataatctt
    42541 ttgtacatga actccactct atagattgta tattacgctc ttcttgctaa atttaattat
    42601 accatatttt gtaatatcag ttaagagttt gcactacaat aatcagaaag cttgttccac
    42661 tcacaatcaa cccctattat tttaagaata tcattgactt ggctatttaa atctttaata
    42721 tctgatttag acattaaagg atctttcatt atttcattta gaaaaatact atcaatgatt
    42781 aaacatacat tttctgataa atattcacgt tttactgaga ttactgttcc aactgtactt
    42841 tcttttagtg tcttatatgc tacactcaat atgcatggtt ctaaattaat tccttctagt
    42901 actgtttcaa agtaatattt tattcttata ttttcatttc caataaatat ttcttcattg
    42961 ctgcttatct tctttaattt tctcattatg cctaacatct tagcattcac ttcatagttt
    43021 attccacatc tctttgatgc taaactcgac atcaagtctc tttctgaata aattacccat
    43081 tgaccattat aggaaaatga tgttttagcg atatccattt ctccttttcc agtaatatta
    43141 aatttaggct ctagtttatt tattaagtaa atctcataaa aatccatagt atatttatta
    43201 tctaattcta tatactcaaa tcttaaattc ttattacacc aattttcttt tttattactt
    43261 aaatgactag cgtgtctatc gcagatattc tctgttttcc caacgtataa acattcttcc
    43321 gtatctagat taatatattt ataaacataa tacatttttt attttctcca attattattt
    43381 atagtaatat ccttcttcat ttactagacc ttgatcaaat aaatttctcc taacagtttc
    43441 aagtctgaca ggatctttgc tataatcaac ttctctttct tcttttttaa catcttcatc
    43501 atcccaatac ttatccaatt cttctttaaa ctttaaatca tctttttgat gaattataac
    43561 ttcacttatt ttatttgaaa gtgttgattt aaaaaaatca taattctttg tatttataat
    43621 atcagtatta tctctttcaa atgctatagc aatagactta ttaaaagcat tcagataaac
    43681 atctttctta aaatcaaact ctttaaaatc ttctttaaat agtttaatcg tccctgttgt
    43741 aaaaatattt tcatttggta tataaaaact aaaagacact tcattgtcct gcttcttttt
    43801 aggtatataa tcttcaacca atatatcttt atcaaaatat tttctaggtt cataatctat
    43861 cacagaaaaa attatttcat ctatttttct attttttctt ttttcttctt ttattgaaac
    43921 aaccatgttg ccttttttat ttatttcatt cattgctctt tttagaacat tttgtttaaa
    43981 atatttatac tctggatata cattatcttt taatttcaaa taaaatctta attcatctaa
    44041 cttatatttt atctccactt ccttattttc tctgctccat agtctaaata aagtgtataa
    44101 cctctgagta tatgcacctc taaaattaaa taacactgat aaattaatag ctgtatatcc
    44161 atttttcttt ttctgcattt ttacaaaatc agttatatga ttgtatagaa cttcatgcat
    44221 cataattgta taaatttggt ctgtatgatc caattcatat gtattaatta aaccacttcc
    44281 aaaagttttt aacttgccag ttgtctcttc tatatagtca aattccaaaa cactttgttg
    44341 aaacatgttc aaaatttctt ttatattttt atgctcataa tcattattgt ttttcataaa
    44401 tacttttagt tcttcttttg atatagttgt aacataagat gaattttgct gtttctgagc
    44461 attaaaaagt attttgtaaa ataatttatt ttccacattt gtaaaatcat atttactttt
    44521 tattaaatta tttggttgca ttaaaatttc ttttttttcc aaaatctatc acctcatata
    44581 aattataata cctaatttat aaaaaggtca accatttttg aaagacgctc acctttgacc
    44641 cttaaaatga tgacctttga cccttaaaat gatgaccttt gacccttaaa atgatgacct
    44701 ttcatctctg aaacctagat ataccaatta ttatagcttg tctaaaaact attaaagact
    44761 ttaaaaactg ttttaaaaac tattaaagac tagaaaagat gttctgaact attctttttt
    44821 tatattaaaa aactttagta tttatttttc tagtatactt taaacactta ctaaaaataa
    44881 tttcttataa aagattggag atgaagaatt ttttatgctt gaaaacagaa aacaaattca
    44941 gaaagaaatt tacttaccaa tagcaacata ttgtttaaaa gataagcaat attatataaa
    45001 agaatatgga gcactattaa taaagagtgc tgaaaatagt gacattttta atacccataa
    45061 aaatagaatt ttgtataaga ataaacttga tattcaagaa atagcaaatg aactgaatgt
    45121 aaataaagca acaatccaaa gaaatataaa aaaactagag aagttagatt ttaaaattct
    45181 aaaaatagaa aataccctaa atggaattgt atattgttta ccatcagaaa ataatattga
    45241 tttaaacaaa tttgcattga taaattatga aatgcttaaa aaaatggtca ataaatttaa
    45301 atcaaataca ataaaagtat attttttact taaaacaatc actacagaaa ctaattttaa
    45361 acctgcaact aatagtttta tagcagaaaa tataggacta agttctaaaa gtaaaaataa
    45421 tttagatatc ataacttctt ctgttaaaac tttagaagaa aataaataca ttgaaacaaa
    45481 aaaagtaaat gtatatgaat atgacaaaga aaaacttaga gaagttccaa aaataagaaa
    45541 agtttatcgg atttgtaatt ttgatgagtg gaaaaaggaa attgataaaa ataaagttta
    45601 ttaaatatag cttaaaagca tttaaaggct tgtctgacgt gttttaatta caaacttgat
    45661 gttatttacc taaaaagata caaatttgct taaaaatgga aatagaaggt caaatatata
    45721 aatagagaac caaataaaat tatattggct ctctatttat cttcttccca atcctcaata
    45781 aacttttcta aactttttaa tttattttca gacacttctt catcatcatg cagagcactt
    45841 ataaaacttt caaaagaatt tttgtgaaag aaactaaaga aacttttagt ctcaactttt
    45901 aaatattctt ctttttctat taatgcttta taatatgtaa atctatcttt cttaacaacc
    45961 tctaaaaatc ctctaccaac taatctcctc aagaaagtta acatagttga ttttttccat
    46021 tcgtactttt cgcctagtgt cttcaaaatt tcagtagatg caacttcttt atcttcgctg
    46081 tcccaaataa acatcataac caacaattca ctttctggaa tcttttttat cttcataaag
    46141 tacaccacct tctaaaagta tatctaaaat actataacaa tagagttaac tacacaatac
    46201 taaatgtcta aaaatgtttt accaattttt accaattaat ttttcttt
//
LOCUS       DAYAOO010000027        45453 bp    DNA     linear   BCT 12-OCT-2024
DEFINITION  TPA_asm: Clostridioides difficile isolate ST8-SSI-h139-18
            SAMN40601845-rid21577343.denovo.027, whole genome shotgun sequence.
ACCESSION   DAYAOO010000027 DAYAOO010000000
VERSION     DAYAOO010000027.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN40601845
            Sequence Read Archive: SRR28438827
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 45453)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 45453)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-MAY-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-MAY-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002157583.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002157583.1
            Genome Coverage       :: 163x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/11/2024 16:19:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 4,038
            CDSs (total)                      :: 3,963
            Genes (coding)                    :: 3,930
            CDSs (with protein)               :: 3,930
            Genes (RNA)                       :: 75
            rRNAs                             :: 6, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 60
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 33
            CDSs (without protein)            :: 33
            Pseudo Genes (ambiguous residues) :: 0 of 33
            Pseudo Genes (frameshifted)       :: 7 of 33
            Pseudo Genes (incomplete)         :: 25 of 33
            Pseudo Genes (internal stop)      :: 11 of 33
            Pseudo Genes (multiple problems)  :: 8 of 33
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..45453
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN40601845-rid21577343.denovo.027"
                     /isolate="ST8-SSI-h139-18"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Denmark"
                     /collection_date="2018"
                     /collected_by="Statens Serum Institute"
     gene            complement(164..1522)
                     /locus_tag="ACGI5H_001645"
     CDS             complement(164..1522)
                     /locus_tag="ACGI5H_001645"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008624114.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PFL family protein"
                     /protein_id="HFG9697355.1"
                     /translation="MVNVGNILETIKMIDEEQLDIRTITMGISLLDCIDPDGDKAREK
                     IYNKIMSSAKDLVKVGKDIEREFGIPIVNKRVSVTPISIIAGATDENDYVKFAQTLDK
                     AAEDLGIDFIGGFSALVQKGYTKGDKILIKSIPKALASTNKVCASVNVGSTRCGINMD
                     AVKEMGEIIKETAELTKDAKGFGCAKLVVFCNAVEDNPFMAGAFHGVGEADRIINVGV
                     SGPGVVKRALEKVKGEPFDVVSETVKKTAFKITRVGQLVAKEASSRLDVPFGIIDLSL
                     APTPAIGDSVANILEEMGLEVVGTHGTTAALALLNDAVKKGGVMACSHVGGLSGAFIP
                     VSEDAGMIDAVIKGALSIDKLEAMTAICSVGLDMIAVPGNTTAGTLGAMIADEAAIGM
                     INNKTTAVRIIPAPGCDVGDMVEFGGLLGRAPVMPINTNSSELFTQRGGRIPAPIHSF
                     KN"
     gene            complement(1545..1814)
                     /locus_tag="ACGI5H_001646"
     CDS             complement(1545..1814)
                     /locus_tag="ACGI5H_001646"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416152.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ACT domain-containing protein"
                     /protein_id="HFG9697356.1"
                     /translation="MKAILTVIGKDKPGIVAGISDELYKQNINIVDISQKILQDYFTM
                     IMIVDLEKSLNSFEKTVEDLVERGKKLSVDVKIQREEIFNSMHNL"
     gene            complement(2104..4059)
                     /locus_tag="ACGI5H_001647"
     CDS             complement(2104..4059)
                     /locus_tag="ACGI5H_001647"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893688.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9697357.1"
                     /translation="MKKYEIFIFMSIIVLCFISFPHKVFGQEENCLEDFERWVQENKN
                     NKEEIVYTLSCDMVIDEEFRFYIPYDSNFTIDTNKYKILIKNHGRFIIDDNELNIIGE
                     GGKEGVIHIENGGSISIGINNIIATDGTALYVEEGGDLHIKSSYESVEKIKANGKDAI
                     GIYTENDIRILNKDIEVNGEHAIGVYSKGDVEIEETSIKAYSSNNESGLLKDNNKLAQ
                     SIISESKKVYIIDDYNELIPSIAEDSGYDIVKCCHRGIGVFSDEIKVSKDDKIENIKF
                     PKYMVLETSSGNRLDIDVEWDFTDYYEKLEKGENFNITGKFKTEMLNKEKIIINDDVV
                     PILNVSVIEKKPIDNLELEFQNTKNGYVAVLFYDMPYSASKVFVEYSSDGINWISEEQ
                     EDIRDQAILFFEDFKLRCFRVKVVGGLKEGYSNIVFKPGFIMGGGDNQETPDDEREND
                     DIDGDRGGGGRDDPDRDEDDNNQDGNNGNENNDSNNNQNNNNENNNNENDNSDEKQPN
                     TPKDDVESSTDSNENKNPHDIPKDGNKENNSDKEKGFYNKNSITENDDNYDLSSKLVF
                     GTNEHSFPYRESISNKNQDTNKNKSNISDYDGIINNNYKLESKEYNLKKDIIFLFCIL
                     TPIMIGSILIVNPDTRKSIIKFIKLKK"
     gene            complement(4242..5717)
                     /gene="spoIVA"
                     /locus_tag="ACGI5H_001648"
     CDS             complement(4242..5717)
                     /gene="spoIVA"
                     /locus_tag="ACGI5H_001648"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416145.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003674 - molecular_function [Evidence
                     IEA];
                     GO_process: GO:0030436 - asexual sporulation [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="stage IV sporulation protein A"
                     /protein_id="HFG9697358.1"
                     /translation="MNNNIYEDISKRTQGDIYIGVVGPVRTGKSTFIRKFMEKLVIPN
                     IDNEFKKDRTRDEIPQSGSGKTIMTVEPKFVPADGVEIKIKDTVSLKVRMVDCVGYIV
                     EGALGHEEGGKQRLVSTPWSQEAMTFEKAAEIGTKKVIKDHSTIGIVVLTDGSVTGID
                     RKSYVEPEERVIQELKNLKKPFAVVLNTLSPKSEETSMLRSELEEKYEVPVLPMNVVE
                     MEEEDIEEVMEAVLYDFPLTEIRINLPKWVEGLERNHWIKSSIITTLKQSIIDIGKIR
                     DIEGIIQGFSELEFLEDTGVDNVELGEGVINIDLQTKQDLFYNVLEEKSGFKIEGDYQ
                     LLSLITRLSKVKNEYDKIESALIDAKIKGYGVVAPSLEELSLEEPEIMKQGKQYGIKL
                     KANAPSLHIIKADISTEVSPIVGNQNQGEEMIKYLMEVFEEQPADLWESNMFGKSLHD
                     LVKEQLQSKLYTMPEEIRVKMQKTLQKIVNEGSSNIITILL"
     gene            complement(5889..7184)
                     /locus_tag="ACGI5H_001649"
     CDS             complement(5889..7184)
                     /locus_tag="ACGI5H_001649"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903280.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="nitrate/nitrite transporter"
                     /protein_id="HFG9697359.1"
                     /translation="MSVEVNKPSIWKNFKVLIILFVAGAFIYALPYLKNYYYDTFAQA
                     FNLTNTQMGSLGSIYGLLAMVSYLFGGFLADRISARKLLSGSLIITGISGLVLTLYPP
                     YIVVFLIHALWGITTILTFWPALVKAVRMLASENEQGKAFGFMESGRGITNAIHLSLV
                     LILFGYISSKVSDESGLTAIIVLYSAINVIVGVLVFFKLKDNEKEVSAKFDKEAFFAV
                     IKMPHTWIITIIMFCSYSANMSFYYFTPYSTEAFGATVVFASAISILAQYCRPVASAA
                     SGLLGDKVGSSKIISYGFILMIAGLLGVIFTPTKSSMIYILLIGCVAIYVSMYAIQGL
                     HYSLLEEGNYSLSISGTAIGIVATLGYLPEVLCPLAAGKILDAFPGVTGYRYYFIVLT
                     IVAIIGLVFTFIWMNMTKERRKELIEMNNNSNENTTKVS"
     gene            complement(7368..8813)
                     /locus_tag="ACGI5H_001650"
     CDS             complement(7368..8813)
                     /locus_tag="ACGI5H_001650"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426942.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="APC family permease"
                     /protein_id="HFG9697360.1"
                     /translation="MSLNKFEIGGITVKKKIGFWDLVFMNISALFGIRWIAKSTASSF
                     GLGLGSIPVWLLFAFIFFVPASLICAELAATYPKDGGLGEWVKQAYGEKWGFMVSWLN
                     WTSKIFWYSSFLTFLAINIAYMLGNPDLSNNKMFILALSLIIFWLLSLVSTRGMAFGK
                     FFTNTGALGSTIPAILLIVMAFMSVVILKKAPSASIYTIQNIIPKIDANSLVSISAII
                     FALSGAETTANFITEMDNAKKNFPKAILTVAVLIGGIYILGSVAITMILPPDKIAAST
                     GILDALAKVAQDLGIGSWFIRIVAFGITLSVLGALILYIAGPVKMLFGNVREGVFPKQ
                     LTVTNKYNIPSNAVIVQAIIVSLLLVGTNLLPSVDNIYNVLVTMTALTALFPYVLLFT
                     SYIRLRKTRPNEERPYSIAKSDSVCINIARMVLVVTVVGILFSTAPVMETLKDNIIYE
                     IEMIGGGLFVIITGLMLWKNYEKKISNNSGC"
     gene            complement(8829..9968)
                     /locus_tag="ACGI5H_001651"
     CDS             complement(8829..9968)
                     /locus_tag="ACGI5H_001651"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454949.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008233 - peptidase activity [Evidence
                     IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="M24 family metallopeptidase"
                     /protein_id="HFG9697361.1"
                     /translation="MSNNMRLERLRKYMNEKSIEIALIFEPDNQFYISGFKAITYSRP
                     IVTVVTQDKIELIVPGLEELHAKEVAKVDNVYVYYEIPEMKEHGISHKHYLDIILNKY
                     PKGTTVGIEKDIVSASFSEYITDKSFAIKDVGSKIFEMRYVKDAKEIEFLKIAGYLSD
                     IGIKGSLENVRVGMSELEFDVAGDNALLKYVSENYPDTYIGFANWTCSGIDRTAQPHL
                     DSNTRILQRGDIVIHSRQVWYENYRAENERTFIIGKPTERQKEVFKIAVEAQQAGLDT
                     IKAGIPARMVDEAARAVVAKYGLELYSNHRIGHGLGLSEHEEPYLRFDNELILEEGMV
                     FSMEPGIYIPGVGGFRHSDTAIVGKNGATIITNYPRSVEELILDI"
     gene            10287..10937
                     /locus_tag="ACGI5H_001652"
     CDS             10287..10937
                     /locus_tag="ACGI5H_001652"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426952.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HFG9697362.1"
                     /translation="MTNKELQKKRILMYFIEAAQNIMENEGIENITLRKVADMAGYNS
                     STLYKYFKNLDHLISFASIKYFKDYNLNISRCIENVNDEYKKYIIMWKLFCKHSFDNA
                     QAFYQVFFNLSSDELSYITKQYYDMFPEDLGIHDSDISLMITGESIKERNKILLNNLV
                     DTGYIPAKDLDIINDIIISFYQNLLFLKKNTGKNSDDDELTMKMISSIEYIIKHAK"
     gene            complement(11094..12113)
                     /locus_tag="ACGI5H_001653"
     CDS             complement(11094..12113)
                     /locus_tag="ACGI5H_001653"
                     /EC_number="1.1.1.94"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009906016.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009331 - glycerol-3-phosphate
                     dehydrogenase (FAD) complex [Evidence IEA];
                     GO_function: GO:0047952 - glycerol-3-phosphate
                     dehydrogenase [NAD(P)+] activity [Evidence IEA];
                     GO_function: GO:0051287 - NAD binding [Evidence IEA];
                     GO_process: GO:0046168 - glycerol-3-phosphate catabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent glycerol-3-phosphate
                     dehydrogenase"
                     /protein_id="HFG9697363.1"
                     /translation="MEKVCVLGTGSWGSALALGLAKKGNDVSMWTRKEEQAKKINRTK
                     ENTDYLPGVLFPNNITISTDIEKTIKDCKVIVLAVPSQAVRSTCQKIKPFIKEGQVIV
                     NVAKGLEKGTGLRLSQVCEEELPQNPYVILSGPSHAEEVARDIPTTVVVASKDLKIAQ
                     MIQDLFMSPKLRVYTNPDIVGVELGGALKNIIAFGAGICDGLGYGDNAKAALMTRGIS
                     EMSRLGIAMGANMSTFAGLSGIGDLIVTCTSMHSRNRRAGILIGKGMSLEDTLKEVKM
                     VVEGITATEVAHDVAEKLDIDMPITNAIYSVIKKGSNPKEVGIELMMRSKKHEMEEVV
                     LGDDI"
     gene            complement(12144..12758)
                     /gene="plsY"
                     /locus_tag="ACGI5H_001654"
     CDS             complement(12144..12758)
                     /gene="plsY"
                     /locus_tag="ACGI5H_001654"
                     /EC_number="2.3.1.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426957.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_function: GO:0008374 - O-acyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0006654 - phosphatidic acid biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycerol-3-phosphate 1-O-acyltransferase PlsY"
                     /protein_id="HFG9697364.1"
                     /translation="MEIFSYIIIAVVAYLLGNISTSYIVAKRIAGVDIRTQGSGNAGS
                     TNVLRTLGKRAGAMTFLGDVLKGVMAVLISEFAARLVGIDTLLAGYLAVICVVAGHNW
                     PAVLGFRGGKGVATSLGAMLAVNPVITLMCLAVFILVVAITKYVSLGSVVGIGCSPIF
                     MIMVKNKAGLIVALFLTASVIYNHRANIKRLLNGTERKIGQKKE"
     gene            complement(12793..14118)
                     /gene="der"
                     /locus_tag="ACGI5H_001655"
     CDS             complement(12793..14118)
                     /gene="der"
                     /locus_tag="ACGI5H_001655"
                     /EC_number="3.6.5.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426959.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0003924 - GTPase activity [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_function: GO:0043022 - ribosome binding [Evidence IEA];
                     GO_process: GO:0042254 - ribosome biogenesis [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome biogenesis GTPase Der"
                     /protein_id="HFG9697365.1"
                     /translation="MSISRPVVAVVGRPNVGKSTIFNKFAGKRISIVENTPGVTRDRI
                     FAEVEWLDKYFTLVDTGGIEPDSEDIILSQMRNQAMLAMDMSHVILFIVDGKAGITAA
                     DKEIAQLLRKTKKPVILVVNKIDSQSQFDNIYDFYELGFGTPFAVSGANSMGFGDLLD
                     EIVENFPAGLDTEYEEDIIRVAITGKPNAGKSSILNKILGEERVIVSPIAGTTRDAID
                     TYFEKNGQKFLLIDTAGLRRKSKIYETIEKYSVIRAMSAVDRADVVLIVIDALEGVTE
                     QDTKVAGIAHDEGKGCIFVINKWDLIEKDNKTMSNYTKDIKEKFPFMMYAPIVFVSAK
                     TNQRMNKILDTVEYVSNEHSKRISTSALNEVIGEAVMLNQPPSDKGRRLKIYYGTQTD
                     IRPPKITLFINDKDLTHFSYQRYLENKIRENFGFEGTSIKFEYRQKNKK"
     gene            complement(14146..15474)
                     /locus_tag="ACGI5H_001656"
     CDS             complement(14146..15474)
                     /locus_tag="ACGI5H_001656"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009906018.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF512 domain-containing protein"
                     /protein_id="HFG9697366.1"
                     /translation="MEVNVKKVNNIISKVYKDSIAEEMGIEVGDLLISVNEQPIHDII
                     EYRFLLSDEYLDVEIQKKDGEVYIYEIEKDYDEDLGVEFTNPIIDQAKSCRNKCMFCF
                     IDQLPEGMRETLYFKDDDSRLSFLQGNFVTLTNMSEEDINNIIKYRISPINISVHTTN
                     PELRQKMISNKFAGKLYGIMKRLADAHIEMNCQIVLCPGINDGKELDRTIKELAQLYP
                     YVNSVAIVPVGITKHRENLVELNIFNDKSASKTIEQIHQIQQKYLEKLGTRFAFLSDE
                     FYILSNSELPGYEEYEGFLQFEDGVGMIRKLKTEIEEYLNILPEKILKREKKVSIATG
                     HSAYEFIQSMADAMMDKFKNLQVNVYEIKNKFFGETITVSGLLTAKDLKEQLEDKELG
                     EALYITRSMLKADEEIFLDNIELNQLEELMRIKIIPCLNEGKDFVDKILK"
     gene            complement(15712..15912)
                     /locus_tag="ACGI5H_001657"
     CDS             complement(15712..15912)
                     /locus_tag="ACGI5H_001657"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454951.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9697367.1"
                     /translation="MGMDIGLNEYTLAIVTLDKNMKNGGGCPIFYANDEKDLQNKALL
                     MSKCVGGMVHDMTNGTLIIVKH"
     gene            complement(15914..16846)
                     /locus_tag="ACGI5H_001658"
     CDS             complement(15914..16846)
                     /locus_tag="ACGI5H_001658"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426964.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YIEGIA family protein"
                     /protein_id="HFG9697368.1"
                     /translation="MDRVFFVAVIIGITSRIIMLNLDQKQYPTQPNVLLSQLILAFVA
                     SSLGALLVPALINRSYTSITFLSLAAEQFRQVRANRRNTLQNLEEVQLVKRGAAFIEE
                     IARTYEVRNYMCIVTSFLTIGLYYVILAETKISEGMSLVISSICGLVLAFILKKLLTR
                     KSIGDIADVMPAEISFVDESILKVGDLKGITNIGLKSDREVYINRGVGIQIIPKNKDY
                     ANAGILFDSGQRQAIVYNIYSRLGLYGDYGEPSFVPLPRRNKEDESIMIAYLPVDKNV
                     EKVMEAVKSCPILSSSKGKNLSLKNYKIGKKGSA"
     gene            complement(16891..17823)
                     /locus_tag="ACGI5H_001659"
     CDS             complement(16891..17823)
                     /locus_tag="ACGI5H_001659"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454954.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YIEGIA family protein"
                     /protein_id="HFG9697369.1"
                     /translation="MEESLLNANLFRHSFIVALVVGILCRGLVLRVTDKQYPSRPQDY
                     LEQIIISGLSASLGAIALPALIDKEFAALTFFAVAIQQFQGLAEQERITLKNIDNEEL
                     VPKGDAYVEEIASTYESRSYISLFSALVSSIVYIVFARKYGLSFFYCTILAIVSGAIV
                     GLIFRRFLRRNSIADIADIVPAKISFEGPILMVNGVIITNIGLESTREKYRNECLAIE
                     VIPRDLGAFGIVNDIGQRQAIIHNLFIHMGIDRDVDEVDIVAISKTNLEKSTVVIPYM
                     PILKDIDVMIDVVKSTPIIETSKGKQSDFSRKTL"
     gene            complement(17878..19167)
                     /locus_tag="ACGI5H_001660"
     CDS             complement(17878..19167)
                     /locus_tag="ACGI5H_001660"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422977.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HFG9697370.1"
                     /translation="MEDLNSIYFFIVMLSIAIVILAVRYTITLRKYLKEFIYVSKKVS
                     NNEYHARLNISAKGELGELARNFNHMIKNMDKTLEEVQYKHLQLRSILKSISHGILAI
                     DVNGNILLINDEAKEMIKSEPNQLVEGHNINVVIKEEEILKQILQFIGSKDNETANIT
                     TKDDIVYKIKVDPVYLQNTNNVIIGSIVNIEDITKKVKLENMRSDFVANVSHELKTPL
                     TSISGFVETLKSNENIDVNTRNRFLEIIESESDRLKRLIDDILLLSFVENKDTLLMEN
                     VVVYDVFKEVYEITQHSASEKNIEVLYKCDDKSISILSNKDYIKQVFLNLVDNAIKYT
                     QDNGIVQVVVLKDEEKIVIKVIDNGVGIPKEDVERIFERFYRVDKARSRDVGGTGLGL
                     AITKHIVKSLNGCIKVKSELGIGSEFIVTILQKNFLK"
     gene            complement(19196..19888)
                     /locus_tag="ACGI5H_001661"
     CDS             complement(19196..19888)
                     /locus_tag="ACGI5H_001661"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HFG9697371.1"
                     /translation="MNTKVLVIDDEMHIVELLKFNLEVSNYEVSYSYDGFDGFIKAKE
                     IKPDLILLDWMLPNISGIEVLRKIRSDKDLKNIPVIMLTAKNMENDKVEGLEIGADDY
                     ITKPFSIKELLARISSVLRRYNLTSLGEENNILTTGNLKLDLSKHEVTKGSEKIELTL
                     KEFELLKLLIQNKGKVLSRNYLLDKIWGYEYYGETRTVDVHIRYLRKKIEDEDKSEKY
                     IETIRGVGYKID"
     gene            complement(19903..20664)
                     /gene="pgeF"
                     /locus_tag="ACGI5H_001662"
     CDS             complement(19903..20664)
                     /gene="pgeF"
                     /locus_tag="ACGI5H_001662"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416109.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidoglycan editing factor PgeF"
                     /protein_id="HFG9697372.1"
                     /translation="MMKDYINIKNVQDIKEYVNLSGNCEELDEKLNSVNLVITCKNID
                     AKNREDMLKVCKECDLTFENLTSNSQIHSDIVNIVNKDTIGKRRDGDALITNLEKVPL
                     LLFTADCVPISIIDAKNKAIGLAHAGWRGTFSNIGHKTIKLMSECYKTVPEDLVCIIG
                     PSIGPCCYEVSEDLVEKFNTILTNNDEKFYIIKEGSYYLDLWKINEYMLRCSGVKKEN
                     IINLNLCTSCRADKFHSYRKHNKASERIGTVLQIK"
     gene            complement(20661..21122)
                     /gene="nrdR"
                     /locus_tag="ACGI5H_001663"
     CDS             complement(20661..21122)
                     /gene="nrdR"
                     /locus_tag="ACGI5H_001663"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454958.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA];
                     GO_function: GO:0140110 - transcription regulator activity
                     [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator NrdR"
                     /protein_id="HFG9697373.1"
                     /translation="MQCPYCNYKESKVIDSRHTDLKSIRRRRECESCKKRFTTYEKIE
                     TTPLMVIKKDNSREYFDREKIKYGLLKACEKRPVSIDEIESIVVHIENEINKCFIEEI
                     ETKKIGEMVMDKLKELDEVAYVRFASVYRQFKDINTFVNELKSILIEKGDK"
     gene            complement(21144..21407)
                     /locus_tag="ACGI5H_001664"
     CDS             complement(21144..21407)
                     /locus_tag="ACGI5H_001664"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416105.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003674 - molecular_function [Evidence
                     IEA];
                     GO_process: GO:0030436 - asexual sporulation [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="YlmC/YmxH family sporulation protein"
                     /protein_id="HFG9697374.1"
                     /translation="MIRVSDIMEKEIINVKNGKRMGFIIDIDMDIHEGKVVSFTIFGD
                     GSRSFFSRGGDEEVIFWNDILKIGCDTIIVNIGSELSLDEFEI"
     gene            complement(21511..22284)
                     /gene="sigG"
                     /locus_tag="ACGI5H_001665"
     CDS             complement(21511..22284)
                     /gene="sigG"
                     /locus_tag="ACGI5H_001665"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416101.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA polymerase sporulation sigma factor SigG"
                     /protein_id="HFG9697375.1"
                     /translation="MQVNKVEICGVNTSELPVLKNKQMKELLLQIKNGDEEARQQFVR
                     GNLRLVLSVIKKFNNRGENIDDLFQIGCIGLIKAIDNFDLSQNVRFSTYAVPMIIGEI
                     RRYLRDNNPIRVSRSLKDIAYKALQVRERLIRTNSKEPTVSEIAKELELEVESVVMAL
                     DAIQDPISLFDPVYQDNGDAIFVMDQVQDKKDTDENWLQEISLKEAIKKLNSREKLVL
                     DLRFYKGRTQIEVADEIGISQAQVSRIEKNALKNMRKYV"
     gene            complement(22376..23098)
                     /gene="sigE"
                     /locus_tag="ACGI5H_001666"
     CDS             complement(22376..23098)
                     /gene="sigE"
                     /locus_tag="ACGI5H_001666"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416098.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_function: GO:0016987 - sigma factor activity [Evidence
                     IEA];
                     GO_process: GO:0006352 - DNA-templated transcription
                     initiation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="RNA polymerase sporulation sigma factor SigE"
                     /protein_id="HFG9697376.1"
                     /translation="MLRLKERIISFITMLGIKLKIIKPKGIYYMGGANILPPPLKPEE
                     EMELLQKLETDESVKSILIERNLRLVVYISRKFENTGIDVEDLISIGTIGLIKAVNTF
                     KLNKNIKLATYASRCIENEILMYLRKNNKKKTEVSFDEPLNIDLDGNELLLSDVLGTE
                     NDEIYKIIEEEIDRDLLVMALDRLSDREKQIMELRFGLIDKGIEKTQKEVAGMLGISQ
                     SYISRLEKKIISRLQKEMKKFV"
     gene            complement(23123..23968)
                     /locus_tag="ACGI5H_001667"
     CDS             complement(23123..23968)
                     /locus_tag="ACGI5H_001667"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009906021.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-E processing peptidase SpoIIGA"
                     /protein_id="HFG9697377.1"
                     /translation="MVYIEYYVIENLVINYIIISCTSILTKRYNPKKNKLLGASLGGA
                     YSVAYLYPSMNILFTVPFKIIIMSIITLISFRSKSKKDYVHVALVFYLVNIFISGSTY
                     FIIYFTGISHLKISFLIACTYVSCELLKYIYKDLKMLKYIKELTKTININLLEKSFCC
                     KALVDSGNLLKDPISQSDVIIVKSSVLEGFIPEKLLNINYEDIDMKKAQEIIGSLDDK
                     TSGRVRIIPYKHAGSNKTSIIIGLKADYIEVDEQKIGNIILGISNFNDREYGAIMNPN
                     ILPGF"
     gene            complement(24285..25559)
                     /locus_tag="ACGI5H_001668"
     CDS             complement(24285..25559)
                     /locus_tag="ACGI5H_001668"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426980.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter substrate-binding protein"
                     /protein_id="HFG9697378.1"
                     /translation="MIKLKKVLSLVMVGILSVSILAGCSKKEDSKGKEGKEKLVVWSA
                     PLTDHDADAWKPIFEKFEKENNCEIEFQIVPWDNYAEKYATAISAGEGPDIGYMYAEM
                     FPQFIEMGAVEDLTPYLEKSGTSDNYLYLDDAKMMGGIYGLPIEAANPGVLYYNKDIL
                     EKLGEKPPKTWDDFKRICEKATKDTDGDGKIDQWGLAQGWGSKVFGSLNWNWYPYLWQ
                     AGGDIYNDDLKSVKFNNAEGLKAANFINDMKKYIPEDALSKDSNEMIESVFGPGKAAF
                     TIMLSSAATSTFDKSFPDLNWGYVTSLEDKTVGSFASVDDLTLMSACKNKELGFKLLE
                     YMLSKESMEAFHKEIPRAPVAKGEKYQGDPRFEEMVTRDKHMYRPLTVGPHGVEIYEY
                     LWKQLQMMIAGDITPEQALNESAKYANGLLAQ"
     gene            complement(25843..27000)
                     /gene="ftsZ"
                     /locus_tag="ACGI5H_001669"
     CDS             complement(25843..27000)
                     /gene="ftsZ"
                     /locus_tag="ACGI5H_001669"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009906025.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003924 - GTPase activity [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_process: GO:0000910 - cytokinesis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsZ"
                     /protein_id="HFG9697379.1"
                     /translation="MLNFDVELEECAQIKVIGVGGGGNNAVNRMVEAQLKGVEFISVN
                     TDKQALYTSKAEYKVQIGEKLTRGLGAGANPEVGKRAAEESKDEIVKLLQGADMVFVT
                     AGMGGGTGTGAAPVVAGLAKEMGILTVGVVTKPFAFEGKIRMKNAEGGIAELKSKVDT
                     LITIPNDRLLQIVQKNTSMLDAFAVADDVLKQGIQSISDLIAVEGLINLDFADVTTIM
                     KDKGLAHMGIGSASGETRAIDAARQAIQSPLLETSIQGAKGVLLNVTGGPNLGLFEVN
                     EASTLVMESCDPEANVIFGASIKEDLGDEIMITVIATGFEGLQNGALDLDTKPKSSIR
                     SSLNTTVKQAVKEIEEEVIAEEKIEPPKKASIIEEDDDESMEIPTFLRRRR"
     gene            complement(27190..27543)
                     /locus_tag="ACGI5H_001670"
     CDS             complement(27190..27543)
                     /locus_tag="ACGI5H_001670"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426985.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="small basic family protein"
                     /protein_id="HFG9697380.1"
                     /translation="MLWVLGGLAFGVVVGYYIPFTYSMDYSIYMSVAILAIMDSIFGA
                     IKSNFEDNYDNVIFITGFIGNAILAILLTYIGEKLGVSLYYVAVLVFGMRLFNNLSII
                     RRYIISNIMNKKRKN"
     gene            complement(27642..28316)
                     /locus_tag="ACGI5H_001671"
     CDS             complement(27642..28316)
                     /locus_tag="ACGI5H_001671"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728479.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF881 domain-containing protein"
                     /protein_id="HFG9697381.1"
                     /translation="MKKKIVILGAFILGVFISTYIKSLDPNRVYITLGQTESIESEVE
                     NTKKEIKNLKETLKNNKKTLNEYKEAKKNGNESIQTLMQKELEEVKELSGYSTVTGPG
                     ITITMRDSERELKDGQNPNDLIIHDIDILRVLNDLKKAGARAISINGERVLATSKIKC
                     SGATITVNDTTYGQPFIIKAIGDIDLLSAAINSPESYAKSLKDIYGINIKVQENNGNK
                     VDLFAK"
     gene            complement(28321..29019)
                     /locus_tag="ACGI5H_001672"
     CDS             complement(28321..29019)
                     /locus_tag="ACGI5H_001672"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416078.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF881 domain-containing protein"
                     /protein_id="HFG9697382.1"
                     /translation="MKKRFINKSIIIGSIVLGVLVSLQLKIINIENRGMTTFKRGEQL
                     TEELKSLKKEKENLQSEVNSVKKDIETYRGKNNEGEQDILKSEIEKYETLAGYTDVEG
                     TGIKIEINSTKDLGNSDKNDSILYNYDLLLSMINKLNSAQASAISINDQRIVSNTYMY
                     LKEDKLYMNDTVIKEPIIIKAIGDSDTLASALNIKYGIVWEIETYYNAKVKVTKEDNI
                     EINGHSDINKAEGK"
     gene            complement(29042..29782)
                     /locus_tag="ACGI5H_001673"
     CDS             complement(29042..29782)
                     /locus_tag="ACGI5H_001673"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416077.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FtsQ-type POTRA domain-containing protein"
                     /protein_id="HFG9697383.1"
                     /translation="MKKRRKLNTNNVMIVLVFILMLSFCICIIVKSDLFDVKKIDVIG
                     NKRVTKSNIMKELNVNLNENIFAYNFKDMKNKLIKNPYIENVEIKRKLPNKIIISLKE
                     KEIFAVLKDEDNYCYIDKKGNLLEELRGSNESKKDLIVDVDYSIDDNKSIKFKNYKTK
                     ENVFKTLNYLKEEGIYRKINYVNLKKESNIEMLTRSNIKILLSNDDNLDYNISRVSKI
                     LIDLQNKNTNGGTINLNYGKLAVYSPEG"
     gene            complement(30052..31278)
                     /gene="murG"
                     /locus_tag="ACGI5H_001674"
     CDS             complement(30052..31278)
                     /gene="murG"
                     /locus_tag="ACGI5H_001674"
                     /EC_number="2.4.1.227"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893705.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0050511 -
                     undecaprenyldiphospho-muramoylpentapeptide
                     beta-N-acetylglucosaminyltransferase activity [Evidence
                     IEA];
                     GO_process: GO:0009252 - peptidoglycan biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="undecaprenyldiphospho-muramoylpentapeptide
                     beta-N-acetylglucosaminyltransferase"
                     /protein_id="HFG9697384.1"
                     /translation="MKVLLSGGGTGGHVYPAIAIANKIRDEHPDAEIIFVGTEKGIES
                     EIVPKYGFELKTVTVQGFKRKIDFDNVKRVFKLFKGLEQSRKIVKKFKPDIVIGTGGY
                     VSGPVLFNASMGKIPAIIHEQNSFPGVTNKILSKTVTKVLTSFEDSHKRFPEAAEDKL
                     VFTGNPVRKEILLSRKNIARKNLSISDEKRMVLCYGGSGGSRKINDAMRLVIKNMVNE
                     DIAFIFATGKSYYDEFMGSISDINLKPYQKVVPYLEDMANALAASDLVIGSAGAISLA
                     EITALGKPSIIIPKAYTAENHQEYNAKSIEKQGAGIAILEKNLTPESLNTAVFKLLGD
                     RELLVDMANASKTIGKPEAIDLIYDEIMKVYNSTQKSTSKKTKKEKVIKEVKEIKKET
                     TPSIEGQAKVIGIKKR"
     gene            complement(31296..32426)
                     /gene="spoVE"
                     /locus_tag="ACGI5H_001675"
     CDS             complement(31296..32426)
                     /gene="spoVE"
                     /locus_tag="ACGI5H_001675"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426995.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0003674 - molecular_function [Evidence
                     IEA];
                     GO_process: GO:0009252 - peptidoglycan biosynthetic
                     process [Evidence IEA];
                     GO_process: GO:0030436 - asexual sporulation [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="stage V sporulation protein E"
                     /protein_id="HFG9697385.1"
                     /translation="MPKENLKKQIDIRVKTEFDGVVFYTTMLLVFVGIVMVFSASFIQ
                     SSFKHNDAYYFLKKNVIYAVLGFIVMIITSRIDYSFWKKNATAIGAIAVVLLLLVLTP
                     LGIEANGAKRWLGIGALTFQPAEIAKFATIILTAKLIEKNYDKIKSLTKGVVPLLVVP
                     GIFFALIILQPNLSTAGTVILVTFVMIFVAGMDMKIVFAMIGSGAALFAALVIAEPYR
                     LSRVTSFLDPFQDPLGKGYQVIQGLYALGSGGLFGLGLGKSKQKYFYIPEPQNDFIFA
                     IIGEELGLIGCIIVIMLFVVLVYRCVRIALKTSNVFACMVVIGIGAQIGIQAALNIAV
                     ATSSMPATGVALPFISYGGTSLTIFMGAVGIVLNISKHVKIN"
     gene            complement(32478..33833)
                     /gene="murD"
                     /locus_tag="ACGI5H_001676"
     CDS             complement(32478..33833)
                     /gene="murD"
                     /locus_tag="ACGI5H_001676"
                     /EC_number="6.3.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454967.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0008764 -
                     UDP-N-acetylmuramoylalanine-D-glutamate ligase activity
                     [Evidence IEA];
                     GO_process: GO:0008360 - regulation of cell shape
                     [Evidence IEA];
                     GO_process: GO:0009252 - peptidoglycan biosynthetic
                     process [Evidence IEA];
                     GO_process: GO:0051301 - cell division [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramoyl-L-alanine--D-glutamate
                     ligase"
                     /protein_id="HFG9697386.1"
                     /translation="MDLKGKKVLLVGLAKTGISTIKHLDKLGASIIVNDIKDENKLRN
                     ILDELKSINDIKYILGHHPEDVDDIDMVVVSPGVPLDLPFILKLKNSGKYIIGEVELA
                     FKLSDNPIFIGITGTNGKTTTTSLVGEIFSRAKRDTYVVGNIGNPVIDTIETSSEESV
                     LVTELSSFQLESIDEFRPKVSAILNITEDHLNRHHTMEKYIEAKANIFMNQTVEDFCV
                     LNYDDEIVKSLADKCNAKVIYFSRTKKVNGGVYLENNDIIIDIDDKIKFLNKDDVSLP
                     GGHNLENCMAAIAIAYVCKIDLEVIKDVLMTFKGVEHRQEFVRNLDNVIYVNDSKGTN
                     PDSTIKAIQSYDRPIILIAGGMDKGSNFDELLETAKSYVKSLVLLGETASNIENCAKN
                     KGFNDIHIVKDMEEAVKTSYEISKSGDIVLLSPACASWDMYESFEVRGKDFKDNVNNL
                     K"
     gene            complement(33852..34820)
                     /gene="mraY"
                     /locus_tag="ACGI5H_001677"
     CDS             complement(33852..34820)
                     /gene="mraY"
                     /locus_tag="ACGI5H_001677"
                     /EC_number="2.7.8.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416067.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0008963 -
                     phospho-N-acetylmuramoyl-pentapeptide-transferase activity
                     [Evidence IEA];
                     GO_process: GO:0009252 - peptidoglycan biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phospho-N-acetylmuramoyl-pentapeptide-
                     transferase"
                     /protein_id="HFG9697387.1"
                     /translation="MMLGITELTYTALIAFLIVIIIGPIFIPMLRKFKFGQTVRDDGP
                     QTHLAKNGTPTMGGIIMIVAILITGLTRVKVSHDMAVGLICIAGFGFIGFLDDFIKIK
                     LKRSLGLKAYQKIILQVALSFYVAFYQYTSSSSASQLMIPFTDFVINVGILYIPIMMF
                     IIVAIVNAVNLTDGLDGLASGVTLIVSVFFMLFASSIAGNTEVAVLAAATVGACLGFL
                     GFNSYPARVFMGDTGSMALGGAVVAFSVLTNSVLIIPIIGGIYFAEALSVLIQVGYFK
                     ATRKRFFKMAPIHHHFEQCGWPETRVVFIFWIITVVLAWISIIAVF"
     gene            complement(34861..36234)
                     /gene="murF"
                     /locus_tag="ACGI5H_001678"
     CDS             complement(34861..36234)
                     /gene="murF"
                     /locus_tag="ACGI5H_001678"
                     /EC_number="6.3.2.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861626.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0047480 -
                     UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase
                     activity [Evidence IEA];
                     GO_process: GO:0009252 - peptidoglycan biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-
                     alanine ligase"
                     /protein_id="HFG9697388.1"
                     /translation="MECLTIKELVLATNGKLIYGDYNDCVSDIVIDSREANAQNAFVA
                     IVGENLDGHTFMKSAYDSGCKTFIKNESNGIKLESSDINLIEVKDTSLALGDISKYYK
                     EKFDIPFIGVTGSVGKTTTRDMIYSAISAKLNILKNEKNLNNHFGVPLTLFNLNKEHE
                     CAVIEMGMSGFNEIKYLVDIVNPKIAVISNIGLSHVEKLGSQEGILKAKMEITSNFDE
                     TNTLIVNGDDKFLSTLKEKEHVYKLKTFGFNKNNDVYCESYTMEEDSLTFICVIDGKK
                     EEIFIPTIGEHNIYNAMSAILVGLCLNISLDYIKKGLKNFKGTKMRLDIIKNEKLTII
                     NDSYNASPDSMDAALKILGRYKGRRVAILGDILEMGEISEYGHRLVGKSSMNNTDIII
                     TIGENSVFIGEEAKQLGFNSANIYHFENREDVFNKLNELVKTGDTILVKGSRGMRLEK
                     IVEYLNK"
     gene            complement(36401..38380)
                     /locus_tag="ACGI5H_001679"
     CDS             complement(36401..38380)
                     /locus_tag="ACGI5H_001679"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416063.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008658 - penicillin binding [Evidence
                     IEA];
                     GO_process: GO:0009252 - peptidoglycan biosynthetic
                     process [Evidence IEA];
                     GO_process: GO:0030436 - asexual sporulation [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="stage V sporulation protein D"
                     /protein_id="HFG9697389.1"
                     /translation="MRKVKRISKKRLVLVLILACALFFCLVIRTGYLQLMKGNWLSTK
                     ALEQQTRDIPIEPKRGTIYDRNMKELAVSVTKYTVWCKPVEVEDKKEAAEKVAEILDE
                     DYKDIYALISKKNMALVKVKRWIDDDKASQIRDAKLSGIWVAEDNQRYYPYGNFAPYV
                     LGHTSSDATGISGVEMQYDKKLKGKPGKLIVSTDASGREIPQGMEKYYEPVQGNGLVL
                     SIDEVIQHYTEKAVQKAYELNNAKKVTAIAMNPKTGDILALASKPDYDPNDSRTPIYP
                     YYQEELEKYNDKDKIKGYYQMWRNPAVSDTYEPGSTFKLITSSSALEEGVIKDGEKFT
                     CTGSVTVGGRKIKCWRHYRPHGTQEFKQAVQNSCNPVFVELGSRLGVGKMYDYIESFG
                     LMDKTGIDLPGEAKGILYNEKNVGPVELATISFGQSISVTPIQLITAISSIANGGDLM
                     QPRVVKSYTDNKGNITETVKPKKVRSVISKETSKKMLEIAESVVTEGGGKIAYIPGYR
                     LGGKTGTAQKVIDGKYAPGKYICSFVGIAPCDDPQIVVLAIVDEPTGVSAFGSTTAGP
                     IVKEIMNDSLKYLGVKPVYKEEEKAEYEKKQVKVPDVRNLKIGDAVKALEDAKLKPDL
                     DADIELPEDTKVKDIFPKPGVKVNEDSSITLYFEN"
     gene            complement(38392..38739)
                     /locus_tag="ACGI5H_001680"
     CDS             complement(38392..38739)
                     /locus_tag="ACGI5H_001680"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890875.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9697390.1"
                     /translation="MKKNYKIHNLNEYKNKKKNNYKKRNKKKIGAKCILLIATFSVII
                     LNLCGYSKISEMKYDIYYLQKDLRKKEIVLEELKAKETEKTSIKEIELKAKELLNMDY
                     PKDGQIKYIDVDN"
     gene            complement(39220..40155)
                     /gene="rsmH"
                     /locus_tag="ACGI5H_001681"
     CDS             complement(39220..40155)
                     /gene="rsmH"
                     /locus_tag="ACGI5H_001681"
                     /EC_number="2.1.1.199"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427011.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016434 - rRNA (cytosine)
                     methyltransferase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (cytosine(1402)-N(4))-methyltransferase
                     RsmH"
                     /protein_id="HFG9697391.1"
                     /translation="MEFHHVSVLLNECIENLNIKPDGVYVDCTMGGAGHSKEIVKKLS
                     DKGLFIGFDQDKNAISTAKERLSEYESRVKFVHSNFENIKEELEKIGVYKIDGVLADL
                     GVSSHQLDEADRGFSYMQDAPLDMRMDVRCEFSAYDVVNTYTEDELTKIIKDYGEDNW
                     AKRIAKFIVEERANKPIETTGELVDVIKKAIPKKARIDGPHPAKRTFQAIRIEVNNEL
                     GVITKMINDASSIMNEGGRICIITFHSLEDRIVKNAFKHLASDCICPQHLPICQCDKE
                     SEVKIITRKPILPSEEEIEVNPRSRSAKLRVAEKI"
     gene            complement(40185..40931)
                     /gene="lgt"
                     /locus_tag="ACGI5H_001682"
     CDS             complement(40185..40931)
                     /gene="lgt"
                     /locus_tag="ACGI5H_001682"
                     /EC_number="2.5.1.145"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890879.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0008961 -
                     phosphatidylglycerol-prolipoprotein diacylglyceryl
                     transferase activity [Evidence IEA];
                     GO_process: GO:0009249 - protein lipoylation [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="prolipoprotein diacylglyceryl transferase"
                     /protein_id="HFG9697392.1"
                     /translation="MDRVAFTLFGIDIMWYGILMACGMILGTLIAIKEAKRVGIKEDD
                     VLNIAIIAIPVGLICARIYYVVFNWSYYAQNMSQIFNFRGGGLAIHGGLIGGILAGYI
                     YTKIKNINFLKMADTVILGMPLAQAIGRWGNFINGEAHGGATNLPWGIMVDGVKVHPT
                     FLYESIWDFGIFIVLLLFRKNKKYEGQVIVTYITLYSIGRFFIEGLRTDSLMLGPLRM
                     AQVISLIGVIGGIIAHVYLSKKNKNNISEE"
     gene            complement(41325..42611)
                     /locus_tag="ACGI5H_001683"
     CDS             complement(41325..42611)
                     /locus_tag="ACGI5H_001683"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728480.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="M16 family metallopeptidase"
                     /protein_id="HFG9697393.1"
                     /translation="MEKIVNDILKEEVYYEKLQNGLDVYFMPKRGFMKKYAILATNYG
                     SNDLEFVPIGEDKKIRVNEGIAHFLEHKMFEQPDGGDAFDKFSKLGVNANAFTNFTMT
                     AYLFSATENFYESLEHLIDYVQTPYFTDENVEKEKGIIAQEIKMYNDDPDWNVYFNCL
                     KAMYVNYPARIDIAGTVDSIYKITKEELYKCYNTFYNPGNMALFVVGDLDVEKVIDVT
                     KKSNNYKVDRLSKSIERFYPEEPESVKEKEVIEKFPISMPMFNIGFKDSNVGLKGKEL
                     LRKEIVTDILVGMLFKKGSKLYEDLYMQGLINENFGAGFSSQVDYAFSIIAGDSKEPK
                     KVKEIILDYIEKSKKEGLSKEEFERTKKKKIGSFIKCFDSINFIGNSFISYVFKDINL
                     LDYLDIIKDITFEEVEERLKEHFKEEYCVISIVEPK"
     gene            complement(42626..43891)
                     /locus_tag="ACGI5H_001684"
     CDS             complement(42626..43891)
                     /locus_tag="ACGI5H_001684"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454972.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="M16 family metallopeptidase"
                     /protein_id="HFG9697394.1"
                     /translation="MVNTKKIINLGNNINLTLIKTEKFKSNLISLYVQRLLDEKETTK
                     NALIPSIIASGSAKYPSARAISNKLDDLYGSSMGADAVKRGERQVLSFKVINISEKYL
                     DESIFEEVVEFFNEVINNTLVVDGGFKEEYLNIEKENLREKIQSIINDKKEYAQDKCI
                     EAMCKGERYSVSEFGYEDEIDSITSRELYEHYKNILKTSPIDIVVEGNFDEDKVVDII
                     SKNLKFEREEIINIPRADFIKNVDEVKVIDEQMEITQGKLVMGYRANVDYADIDKYYA
                     LVVGSNVLGGGPHSKLFVNVREKESLCYYIFSSIEKYKSIMFISSGIETKDYDKAVEL
                     IKKQVESVKAGDISDEELENSKLALVNSMKSITDNIGGMSDFVFSQSMAKTNSEVQDI
                     ISSIEKVTKKDIVEAIKNIELDTVYFLRN"
     gene            44207..45304
                     /gene="ychF"
                     /locus_tag="ACGI5H_001685"
     CDS             44207..45304
                     /gene="ychF"
                     /locus_tag="ACGI5H_001685"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416044.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="redox-regulated ATPase YchF"
                     /protein_id="HFG9697395.1"
                     /translation="MKLGIVGLPNVGKSTLFNAITQAGAESANYPFCTIDPNVGVVSV
                     PDERLNKLQELYNSEKIVPTAIEFCDIAGLVRGASKGEGLGNKFLSHIREVDAIVHVV
                     RCFEDENVVHVDGSVDPLRDIETINLELIFSDIEILERRINKTQKAAKADKTLGSELD
                     LLKSIMSTLEESKCVRTMEFTEDEQTFVNSLDLLTSKPVIYASNVSEDDLADNGENNK
                     YVQQVKAFAETEDAEVVVVCAQIEAEISELDSAEEKKEFLETLGLEQSGLDKLIKSSY
                     ALLGLISFLTAGPKEVRAWTIKVGSKAPQAGGKIHSDIERGFIRAETIAFNDLVEHGT
                     MAAAKEKGLVKLEGKEYIVKDGDVILFRFNV"
BASE COUNT        14179 a         8403 c         4759 g        18112 t
ORIGIN      
        1 ttaaatgtcc atgtatcgct ttatttttgc cataatctta ataactgatt tttaaagttt
       61 attatcttaa caaagttcat tatcttatat aatatttaaa tgcataggct tctttaattt
      121 aaccatctaa atatttaatt aaatattatt atatgtaata taactaattt ttaaatgaat
      181 gtataggagc tggaatcctt cctcctcttt gagtaaataa ttcagatgaa tttgtattta
      241 taggcattac tggtgctcgt cctaaaagtc ctccaaattc taccatatca cctacatcac
      301 atcctggggc tggtataatt ctaacggctg tagtcttatt attaatcata cctattgctg
      361 cctcatcagc tatcatggct ccaagcgtac ctgctgtagt atttcctggc acagctatca
      421 tatcaagacc tacagaacaa atagcagtca ttgcttcaag cttatctata cttaaagcac
      481 ctttaataac agcatcaatc atacctgcat cttcagatac tggtataaac gctccactaa
      541 gtcctccaac atgtgaacat gccattactc cacctttttt aacagcatca tttaaaagtg
      601 ctaatgctgc tgtagtccca tgagtaccaa caacttcaag acccatttcc tctaatatat
      661 ttgctactga atcaccaata gcaggtgtag gagctagtga taagtctatt atcccaaatg
      721 gaacatccaa tctactagaa gcttcctttg ccacaagttg tccaactctt gtaattttaa
      781 atgcagtctt tttaactgtt tctgaaacaa catcaaaagg ctctcccttt actttctcta
      841 aagctctctt aacaacacca gggccactta caccaacatt tataattcta tcagcctcac
      901 caacaccatg gaaagctcct gccataaatg gattatcttc tactgcatta caaaatacta
      961 ctaattttgc acaaccaaaa ccttttgcat cttttgttaa ttctgcagtt tcttttatga
     1021 tttctcccat ttctttcact gcatccatat ttataccaca tcttgtagaa cctacattta
     1081 ctgaagcaca tactttatta gtacttgcta gagcttttgg aattgactta attagtatct
     1141 tatcaccttt tgtatatccc ttttgaacta atgctgagaa tccaccaata aaatctatac
     1201 ctaaatcctc tgcagcctta tccaatgtct gtgcaaactt tacatagtca ttttcatctg
     1261 ttgcacctgc aataatggaa attggagtta ctgataccct tttatttaca attgggatac
     1321 caaattcacg ctctatatct tttccaacct tcaccaaatc tttagcagaa ctcataatct
     1381 tattgtatat tttttctcta gctttatctc catcagggtc tatacaatct aataaagaaa
     1441 tccccatagt tatagttctt atatccaact gttcttcatc tatcatcttt attgtttcaa
     1501 gtatatttcc tacattcact attatcacct ccccttactg tctactacag attatgcatt
     1561 gaattaaata tttcttctcg ctgaattttt acatccactg ataatttctt acctctttca
     1621 accaagtcct caaccgtttt ctcaaaagaa tttaatgatt tctctaaatc aactatcata
     1681 atcatagtaa aataatcctg taatattttt tgtgatatat ctactatgtt gatattttgc
     1741 ttgtataatt catcactaat tcctgccact atacctggtt tatcctttcc aattactgtt
     1801 aaaattgctt tcataataat atcctccctt atttttttat aaatcttata tttttacaaa
     1861 ttgaactatg ttttaacata tatttcattt atttgttagt aaaccacttt ttatgtatat
     1921 atttaatata ttttaatacc tatacattca tttgtcaatt ttttttcaat attctattat
     1981 ttttatacta tttagaaaat tcatatatta tatatgtttt ctcaacaata aatacagttt
     2041 tcataataat gaaaggtatt acttagcaat cgcatgattt tctaaataat acctttctaa
     2101 aaattatttt tttaatttta tgaatttaat tatacttttt ctagtatcag gatttacaat
     2161 taatatagaa ccaatcataa ttggtgttag tatacaaaat aaaaaaataa tatctttttt
     2221 tagattatat tctttagatt ctaatttata attattattt attattccat cataatcact
     2281 tatatttgac ttatttttat ttgtatcttg atttttgtta gaaatacttt ccctataagg
     2341 aaaagaatgt tcattggtac caaatactaa ttttgagctt aaatcataat tatcatcatt
     2401 ttctgtaatt gaatttttat tgtaaaatcc tttttcttta tcagaattat tttctttatt
     2461 accgtcttta ggtatatcat gaggattttt attttcattg ctatcagtac ttgattctac
     2521 atcatcttta ggagtatttg gttgtttctc atcagaatta tcattttcat tattattatt
     2581 ttcattatta ttgttttgat tgttattact atcattattt tcatttccat tattcccatc
     2641 ttgattgtta tcatcctcat ctctatccgg gtcgtctcta cctcctcctc cacggtcacc
     2701 atcaatatca tcattttccc gttcatcatc tggtgtctct tggttgtctc cgcctcccat
     2761 tataaatcct ggtttaaaaa ctatatttga atacccttct tttaatcctc ctaccacttt
     2821 tactctaaaa caacgcaact taaaatcttc aaaaaaaagt atagcttgat ctctaatatc
     2881 ctcctgttct tcagatatcc aattgattcc atcgcttgaa tattcaacaa aaaccttact
     2941 tgcactatac ggcatatcat aaaataaaac agctacatat ccattttttg tattttgaaa
     3001 ttccagttcc aaattgtcta ttggtttttt ctctataaca gatacattca aaataggaac
     3061 tacatcatca tttattataa ttttttcttt atttaacatt tctgttttaa actttcctgt
     3121 tatattaaaa ttttctccct tttccaactt ttcataataa tcagtaaaat cccattctac
     3181 atctatatca agtcgattac cactagatgt ttctaatacc atatatttgg gaaattttat
     3241 attttctatt ttatcatctt tacttacttt tatttcatca ctaaatacac caattcccct
     3301 atgacaacat ttcacaatat catagccaga atcttcagct atagagggta taagctcatt
     3361 ataatcatca attatataaa ctttcttact ttctgatata attgattgtg ccaacttatt
     3421 attatctttt agtaacccac tttcattgtt gctactatat gcttttattg aagtttcttc
     3481 tatctcaaca tcacctttag aataaacacc tatagcatgt tctccattca cttcaatatc
     3541 cttatttagt attctaatat cattttcagt ataaattcct attgcatctt tcccatttgc
     3601 ctttattttt tcaacagatt cgtaggatga tttaatatgt aagtctcctc cttcttcaac
     3661 gtataaggct gtcccatcag tagcaattat gttgtttata ccaatactta tacttccacc
     3721 attttctata tgtattactc cttcttttcc tccttcacct attatattca attcattatc
     3781 atcaataata aatctcccat gattttttat caatatttta tatttgttgg tatctattgt
     3841 aaaattactg tcataaggaa tataaaatct aaactcttca tctattacca tatcacaaga
     3901 aagagtataa actatttctt ctttattatt tttattttct tgaacccacc tttcaaaatc
     3961 ttcaagacaa ttttcctctt gtccaaaaac tttatgtgga aaacttataa aacacaaaac
     4021 tattatactc ataaaaataa atatctcata ctttttcatc ttacactcct agaaattttt
     4081 tagctttgaa acaatctgtc gaaacataca cttcacccac tataattttt ccacaattat
     4141 caattattgt caatttataa aagtatcttt attaattgtt ataaataaaa agctacttac
     4201 taaagtaaac agacgtttca ctttaataag tagctatatt tttataacaa aatagttata
     4261 atattagaac ttccttcatt tacaattttt tgtaaagtct tttgcatttt aactcttatc
     4321 tcttctggca tagtatataa tttactttgt aattgctctt ttactaagtc atgtagtgat
     4381 ttaccaaaca tatttgattc ccataaatct gctggttgct cttcaaatac ttccataaga
     4441 tattttatca tctcttcacc ttgattttga tttccaacta ttggagaaac ctctgtagat
     4501 atatctgctt ttataatatg aagtgatggt gcattggctt ttaacttgat accatattgt
     4561 tttccttgtt tcattatttc tggttcttcc agactaagtt cttctaagga aggagctact
     4621 actccatatc cttttatctt ggcatctatt aaagcacttt ctattttatc atactcattt
     4681 ttaactttag atagtctagt tatcagacta agcagttgat aatctccttc aattttaaat
     4741 ccactttttt cttcaaggac attatagaat aaatcttgct ttgtctgtaa atcaatattt
     4801 ataacacctt ctcctagctc tacattatca acacctgtat cttccaaaaa ctctaactca
     4861 gaaaatcctt gtataatacc ttctatatcc cttattttac ctatatctat aatactttgt
     4921 tttaatgttg ttattatgct actttttatc caatgatttc tttcaagacc ttcaacccat
     4981 tttggtaagt tgattcttat ttctgtaagt ggaaaatcat ataatacagc ttccataacc
     5041 tcctctatat cttcttcttc catttcaacc acattcattg gaagaactgg aacttcatac
     5101 ttttcttcca attcacttct aagcatactc gtttcctcac tttttggact taacgtattt
     5161 aaaaccactg caaatggttt tttaagattt ttcaattctt gtataactct ctcttctggt
     5221 tctacatagc tttttctgtc aattccagta actgaaccat ctgtcaagac aactatccct
     5281 attgtagaat ggtcttttat aactttttta gttcctatct ctgctgcctt ttcaaatgtc
     5341 atagcttctt gtgaccaagg agtggatact aatctttgtt ttccaccttc ctcatgccct
     5401 aaagctcctt caactatgta tccaacacaa tctaccattc ttacttttaa agatactgtg
     5461 tcttttattt ttatttctac accatctgct ggtacaaatt ttggttctac tgtcattatc
     5521 gttttacctg aaccactttg gggtatctca tctcttgttc tatccttttt aaattcattg
     5581 tctatattag gtataaccaa cttttccata aattttctta taaaagttga ttttcctgtt
     5641 cttacaggtc caactactcc aatatatata tccccctgag tccttttgga tatatcttcg
     5701 tatatgttat tattcatatt attcctccta tacatctaat cttattaaat tatatttaga
     5761 gttaagggtt aatattctta aaatagaaaa ataaagacca gcaatattaa tttaatttat
     5821 atatagaaat ttgtaaattt caatgtaaat taaattaata ttgctggtcc aaatagtagt
     5881 gtattatatt aactgacttt agtagtattt tcatttgaat tattattcat ctcaataagt
     5941 tctttacgtc tttcttttgt catgttcatc catataaatg taaacaccaa tccaattatg
     6001 gctactatag taagaactat gaagtagtac ctatatccag ttacacccgg aaatgcatcc
     6061 aatatcttcc ctgctgctaa aggacaaagt acttctggaa gatatcctaa cgtagcaact
     6121 attcctatag cagttcctga tattgataat gaataattac cttcttcaag taacgaatag
     6181 tgtaaacctt gaattgcata catagataca tatattgcaa cacatccaat caatagtata
     6241 taaatcatag atgattttgt tggtgtaaat attacaccta aaagacctgc aatcataagt
     6301 ataaatccat aagatataat ctttgatgaa ccaactttat ctccaagtaa tccagaagca
     6361 gctgatgcta ctggtctaca atactgagct aatattgaga ttgcagatgc aaacaccaca
     6421 gtagctccaa atgcttcagt tgaataaggc gtaaaataat aaaatgacat attagctgaa
     6481 tatgaacaaa acattattat tgttattatc catgtatgag gcatttttat tactgcaaaa
     6541 aaggcttctt tatcaaattt tgctgatacc tctttttcat tatcctttaa tttgaaaaat
     6601 actaatactc caactattac atttattgct gagtataata ctataatagc tgtaagacca
     6661 gattcatcac ttacttttga tgaaatatac ccaaatagta tcaatactag agatagatga
     6721 attgcattgg taattccacg accactttcc ataaatccaa aagcttttcc ttgttcattt
     6781 tcagatgcta acattctaac agcttttaca agagctggcc aaaaagtaag tattgttgtt
     6841 attccccata aggcatggat taaaaacaca acaatatatg gaggataaag tgttaataca
     6901 agaccagata ttcctgtaat aattaaagaa cctgaaagca attttctggc tgaaatacgg
     6961 tctgctaaaa aaccaccaaa aaggtatgat accattgcaa gtagaccata aatgcttcct
     7021 aagcttccca tttgtgtatt tgtaagatta aatgcttgtg caaaagtatc ataataataa
     7081 ttctttaaat atggtaaagc atatataaat gctcctgcta caaagagtat tatcaagact
     7141 ttgaaatttt tccaaatgct tggtttattt acttcaactg acatacttcc tccttatgta
     7201 aatacctgta aattttcata ataattaatt attgcttatt ttattgttta ttcaatattt
     7261 aggaatattt attaatatat taggttaatc tatcaataat ttatggtgag ttatgagcta
     7321 aaagtaaact cttttagctc accataataa ttatattttt atttatacta acatccagag
     7381 ttattagata tctttttttc atagttcttc catagcatta aacctgttat tataacaaaa
     7441 agacctcctc ctatcatttc aatctcatag attatattat cttttaaagt ctccataact
     7501 ggtgccgttg agaaaagtat gccaactaca gttactacaa gtaccattct ggcaatattg
     7561 atacaaactg aatcactttt tgcaattgaa tatggtcttt cttcatttgg tcttgtcttt
     7621 ctaagtctaa tataagatgt aaaaagcaag acatatggaa ataatgctgt taatgctgtc
     7681 atagtaacaa gaacattgta tatattatct actgatggta ataagtttgt tcctacaaga
     7741 agtagactca ctattatagc ctgaactatt actgcatttg atggtatatt gtatttattt
     7801 gtaacagtca attgcttagg aaatacacct tctcttacat ttccaaaaag catctttact
     7861 ggacctgcta tataaagtat taatgctcct agtactgata aagttattcc aaatgctact
     7921 attcttataa accaacttcc tatacctaaa tcttgtgcaa ctttagctaa tgcatctagt
     7981 atccctgtag atgctgcaat tttatctgga ggaagtatca ttgttattgc tactgaacct
     8041 aagatataga ttcctcctat taaaacagcc acagttaata tagctttagg aaagtttttc
     8101 ttagcattat ccatttcggt tatgaaatta gcagtcgttt cagctcctga taatgcaaat
     8161 attatagcag atatagaaac taatgaattg gcatctattt ttggtattat attttggatt
     8221 gtatatatcg atgctgatgg agcttttttg agaataacta cagacataaa tgccatcact
     8281 ataagtaata tagcaggaat tgtagaacct aatgctcctg tattcgtaaa aaattttcca
     8341 aatgccatcc cacgagtact tactaaggac aacagccaaa atattatgag tgaaagtgct
     8401 aaaataaaca tcttattgtt tgataaatct ggatttccaa gcatatatgc aatatttatc
     8461 gctaaaaaag tcaagaaaga agaataccaa aatatctttg atgtccaatt tagccatgac
     8521 accataaatc cccacttctc tccataagct tgtttaaccc attctccaag tccaccatct
     8581 tttggatatg ttgcagccaa ctctgcacat ataagtgatg caggaacaaa gaatataaaa
     8641 gcaaacaata accaaactgg tatagaacca agacccaatc caaaactaga ggcagtagat
     8701 ttagctatcc atctaatccc aaatagtgct gatatattca taaatactaa atcccaaaat
     8761 ccaattttct ttttcactgt aattcctcca atttcaaatt tattcagact catacacaat
     8821 gtattgactt aaatatcaag tataagttct tcaacacttc ttggataatt agttataatt
     8881 gtagcaccat tcttacctac tattgctgta tctgagtgtc taaatcctcc aactccaggt
     8941 atatatatcc ctggctccat agaaaatacc attccttctt ctaatattaa ttcattgtca
     9001 aatcttaaat atggctcttc atgttctgat aaacctaaac catgaccaat tctatgattt
     9061 gaatataact ctagaccata ctttgcaaca acagctcttg ctgcttcatc caccattctt
     9121 gctggtatac cagcttttat tgtatctaat ccagcttgtt gagcctctac tgcaatctta
     9181 aacacttctt tttgtctttc tgttggtttg cctataataa aagttctttc attttctgct
     9241 ctatagtttt cataccaaac ctgtctacta tgtattacta tatctcctct ttgaagtatt
     9301 ctagtattgg aatctaaatg aggttgtgct gttctatcaa tccctgaaca agtccagttt
     9361 gcaaatccta tatatgtatc aggataattt tcagaaacat attttagtaa agcattatcc
     9421 cctgcaacgt caaactccaa ttcactcatc ccaactctaa cattttctaa agaccctttt
     9481 attcctatat cagataggta acctgctatc ttcaaaaatt ctatttcttt tgcatctttt
     9541 acatatctca tttcaaatat tttacttcca acatctttga tagcaaatga cttatcagtt
     9601 atatactctg aaaagcttgc agatactata tctttttcta ttccaacagt tgttccttta
     9661 gggtatttat ttaaaattat atctaagtaa tgtttatgtg atattccatg ttctttcatt
     9721 tctggtattt cataatacac atatacatta tcaacttttg caacttcttt agcatgtaat
     9781 tcttctaatc caggtactat taattctatt ttatcttgag ttactactgt tacaattggt
     9841 ctagaataag ttattgcttt aaatccacta atataaaatt gattgtctgg ttcaaatatt
     9901 aaagcaattt caatgctttt ttcattcatg tactttctca atctttctag tctcatatta
     9961 tttgacataa tgcacctctt tcttaatatt cagataattt attcaataca acaaggatga
    10021 atatattatt ttaaaattct taatattttt agtacttgtc gtatttgtat gtaaattaat
    10081 tttatttgtg attattttat cataatcatg attattttgt caatcatgat tttattttaa
    10141 aaaatttttt atattctagt gattttaaat tatctaaaat ataacgagta tacattgtat
    10201 tttgtaatat tattcttgat ttatggtaag tttaatgata aaatcacgat tatataaact
    10261 atattgatta tttgtaggtg aataaaatga caaataaaga attacaaaag aaaaggatat
    10321 tgatgtattt catagaagct gctcaaaata ttatggaaaa cgaaggtata gaaaatatta
    10381 cacttcgtaa ggttgcagat atggctggct ataatagttc aactctatat aaatacttta
    10441 aaaatttaga ccatttaata tcatttgcat ctataaaata ttttaaagat tataacttga
    10501 atatttcaag atgtatagaa aatgtcaatg atgaatataa gaaatatata attatgtgga
    10561 aattattttg taagcattct tttgataatg ctcaagcttt ttaccaggta ttttttaact
    10621 tgtctagtga tgaacttagc tatataacaa aacaatatta tgatatgttt ccagaagatt
    10681 taggtattca tgatagtgac atatctttaa tgattacagg agaaagtata aaggaaagaa
    10741 ataagatact attaaacaat cttgtagata ctggatatat accagctaaa gatttagaca
    10801 taatcaatga tataattatt tctttttatc aaaatctatt attcttaaaa aagaacacag
    10861 gaaaaaattc tgatgatgat gaattaacta tgaaaatgat ttcttctatt gaatacataa
    10921 taaaacatgc taaataaaat taaaatatgg ctgtctcaaa atagagataa gcctttttta
    10981 ttgttgaaat aataaaaata tatttaattt catataaaaa agagtgcctc gtaaactaaa
    11041 aagttcattt tgagacaccc ctaaaataaa tttattattt attatacaat agtttatata
    11101 tcatcaccta aaactacttc ttccatttca tgctttttac ttctcatcat tagttctatt
    11161 ccaacttctt taggatttga acctttcttt attacagaat atatagcatt agttataggc
    11221 atatctatat ctaatttttc agcaacatca tgtgctactt cagtagcagt tatgccttct
    11281 acaaccatct ttacttcttt taaagtatct tctaaactca tccctttacc tatgagtata
    11341 ccagctcttc tatttctact atgcatactt gtacaagtaa ctattaaatc tccaatacct
    11401 gaaagacctg caaaggtaga catattagct cccatagcaa ttccaagtct gctcatttca
    11461 ctaatacctc ttgtcataag ggcagctttt gcattatcac cataccctaa tccgtcacat
    11521 atcccagctc caaatgctat aatatttttt aatgctcctc caagttctac tccaactatg
    11581 tctggattcg tataaactct aagtttaggg ctcataaata aatcttgtat catctgtgct
    11641 atttttaaat ctttagaagc aactactacg gtagtaggaa tatcccttgc tacttcttca
    11701 gcatgagatg gcccagatag tattacatat ggattttgtg gtaattcttc ttcacagact
    11761 tgagataatc taagcccagt ccctttttca agacctttag ctacattaac aataacttgt
    11821 ccttctttta taaatggttt tattttttgg caagtacttc ttacagcctg tgatggaact
    11881 gctaaaacta ttaccttaca atcttttata gttttttcta tatcagtact tatagttata
    11941 ttatttggaa ataatactcc tggtaaatag tctgtatttt ctttagttct gtttattttt
    12001 ttagcttgtt cctcttttcg agtccacatg ctcacatcat tacctttttt tgcaagccct
    12061 aaagctaatg cacttcccca gcttccagta cctaatacac atactttctc catgtttaac
    12121 accacctgag tataatatat ttactattct ttcttttgac caatttttct ctctgtccca
    12181 tttaataatc gctttatatt tgctctgtga ttatatatta ctgatgcagt taagaacaga
    12241 gctactatta aaccagcttt attttttacc ataatcataa atattggtga acatcctatt
    12301 cctacaacag aacccaatga aacatacttt gttatagcta ccaccaatat aaatactgct
    12361 agacacatta gtgttattac tggatttaca gctagcattg cccctagtga agttgcaaca
    12421 cctttgcctc ctctaaatcc taaaaccgct ggccaattat gacctgctac aacacatata
    12481 actgccagat atccagctaa aagagtatct attccaacca atcttgctgc aaattctgat
    12541 attaaaacag ccattacacc tttaagaaca tcacctaaaa atgtcattgc tcctgctctt
    12601 tttccaagtg tcctaagtac atttgtcgaa cctgcattac cagaaccttg agtccttata
    12661 tcaaccccag caattcgctt tgcaactatg tatgaggtag atatatttcc taaaagatat
    12721 gcaactacag caataattat ataactaaat atctccactg aatttccccc ctttagttat
    12781 attttaagat atttattttt tatttttttg tctatactca aactttatgg aagttccttc
    12841 aaatccaaaa ttttctctta tcttattctc aaggtatctt tgatatgaga agtgagttaa
    12901 atccttatca tttataaaca atgtaatttt aggaggtcta atgtcagttt gagtcccata
    12961 gtaaattttt aatcttctac ctttgtcaga tggtggttga tttaacatta cagcttctcc
    13021 aattacttca ttcagtgctg aagttgatat tctcttagaa tgttcatttg acacatattc
    13081 aactgtatct agtatcttgt tcattctttg attagttttt gcagaaacaa atacgattgg
    13141 agcatacatc ataaatggaa atttttcttt tatatctttt gtgtaattgc tcatagtctt
    13201 attatctttc tctattaaat cccatttatt gattacaaat atgcatcctt ttccttcatc
    13261 atgtgctata cctgcaacct ttgtatcttg ttctgttaca ccttctaagg catctattac
    13321 tatcaatact acatctgctc tatctacagc actcatagcc cttattacac tgtatttttc
    13381 tattgtctca tatattttac tttttcttct aagccctgct gtatctatta gaagaaattt
    13441 ctgtccattt ttttcaaaat aagtatcaat tgcgtctcta gtagttcctg caattggact
    13501 tacaattact ctttcttctc caagtatctt attgagtata gaactttttc ctgcatttgg
    13561 tttacctgtt atagctactc ttattatatc ttcttcatac tctgtatcta atcctgctgg
    13621 aaaattttca actatctcat ctaataaatc tccaaatccc atactattgg ctcctgaaac
    13681 tgcaaaaggc gttccaaatc ccaactcata aaaatcgtat atattatcaa attgactttg
    13741 actatcaatc ttattaacca ctaagattac tggttttttt gtctttctaa gcaattgtgc
    13801 aatttcttta tcagcagctg ttattccagc tttaccatca actataaaaa gtattacatg
    13861 tgacatgtcc attgcaagca tggcttgatt tctcatttga gataatatta tatcttcgct
    13921 atcaggttca attcctcctg tatccactaa tgtaaaatat ttatctaacc attctacttc
    13981 agcaaatatt ctatctcttg taactccagg tgtattttca actattgata tcctttttcc
    14041 tgcaaattta ttaaatattg tagacttacc aacgtttggt ctcccaacta cagctacaac
    14101 tggcctactt atactcattt tatttctcct tccatctttt gttttctatt ttaaaatttt
    14161 atccacaaaa tcttttcctt cattcaaaca agggataatt tttattctca taagttcttc
    14221 taattgattt aattcaatat tatctaagaa aatttcttca tctgctttta gcatacttct
    14281 tgttatataa agagcttctc ctaattcttt atcttcaagt tgttctttta aatccttagc
    14341 tgttaaaaga cctgatacag ttattgtctc tccaaaaaac ttgtttttga tttcatatac
    14401 atttacttga agatttttaa acttgtccat catagcatct gccatactct gtataaattc
    14461 atatgcagaa tgaccagtag ctattgatac tttcttctct ctttttagaa tcttctcagg
    14521 caatatattt agatactctt caatctctgt ttttaactta cgtatcatac ctacaccatc
    14581 ttcaaactgt aaaaaacctt catattcttc atatccaggc aattcactat tagatagtat
    14641 ataaaattca tctgataaaa atgcaaatcg agtacctaat ttttcaagat atttctgttg
    14701 tatttgatgt atttgctcta tagttttact tgcgctctta tcattaaata tatttaattc
    14761 tactagattt tctctatgct ttgtaatccc aactggaact atcgcaacac tgtttacata
    14821 cggataaagt tgagctagtt cttttattgt tctatccaat tcctttccat catttatacc
    14881 tggacataaa acaatttgac agttcatttc tatatgagca tctgccaatc tcttcattat
    14941 accatataat tttcctgcaa atttattgct tatcattttt tgtcttaact ctggattagt
    15001 tgtatgcaca gatatattta taggacttat tctatatttt ataatattat ttatatcttc
    15061 ttcactcata tttgtaagtg tgacaaaatt tccttgtaaa aaagataatc tcgaatcatc
    15121 atctttaaaa taaagagttt ctctcatacc ttctggcaat tggtctataa aacaaaacat
    15181 acacttattt ctacagcttt tagcttggtc aattatcgga tttgtaaatt caacacccaa
    15241 atcttcatca tagtcttttt ctatctcgta tatgtagact tcgccatctt ttttttgtat
    15301 ttctacatct aaatattcat cacttagtaa gaatctatac tctattatat catgtattgg
    15361 ctgttcattc acagatataa gtaaatctcc tacctctata cccatttctt ctgcaatact
    15421 atctttataa accttactta taatattatt tacttttttt acatttactt ccaatatttt
    15481 caccactctt ttgtattcat caatgcttat tataatgtat tttaatatgc aatttattta
    15541 tttattatat tttatgatag catttttaag catttcatgt cataataaca cattttaatt
    15601 ctaatagtca atataagtaa atagctataa aatagattag aacaaataat attcaaattt
    15661 aagtttctta aaaatttaaa tattatttgt tcttaaaaaa attttataaa tttaatgttt
    15721 tactatgatt aacgtcccat ttgtcatatc atgaaccatt ccacctacac actttgacat
    15781 caacaatgcc ttattttgta agtctttctc atcatttgca taaaatattg gacaacctcc
    15841 accatttttc atattcttat caagtgtaac tatagctagg gtatattcat ttaaacctat
    15901 atccattccc atctcatgca cttcctttct ttcctatttt ataatttttt agtgataagt
    15961 tttttccttt agagcttgaa agtattgggc atgactttac agcttccatt actttttcca
    16021 cattcttatc tactggtaaa taagcaatca ttatactttc atcctcttta tttcttctag
    16081 gtaatggtac gaatgaaggt tctccataat ctccatataa acctaacctt gaatatatat
    16141 tgtatactat tgcttgtctt tgaccggagt caaataatat tcctgcatta gcataatcct
    16201 tatttttagg aattatttgt attcctacac ctctattaat atatacttct ctatcgcttt
    16261 ttagacctat atttgttata ccttttaaat ctcccacctt tagtatagat tcgtccacaa
    16321 aactaatttc agcaggcatt acatcagcta tgtctccaat actttttcta gtaagaagtt
    16381 tttttaatat aaaggctaac actaatccac aaattgaact tattaccaaa ctcatccctt
    16441 cacttatttt cgtttctgca agtattacat aatacaatcc tattgttaaa aaagatgtaa
    16501 ctatacacat ataatttctt acttcatagg ttctagctat ctcttctatg aatgcagctc
    16561 ctctctttac aagttgaact tcctctaaat tttgcaatgt atttcttcta tttgctctca
    16621 cttgtctaaa ttgttctgct gctagagata aaaaagttat agatgtataa gaacgattta
    16681 taagagctgg aaccaataat gctcctaatg aagaagcgac gaatgctaat ataagttgag
    16741 atagtaaaac atttggttgc gttggatact gtttttggtc taaattcaac attataattc
    16801 tagatgttat accaataata acagcaacaa aaaatactct atccattaaa tcactcctaa
    16861 aatatttaat ttgaaatttt acatgtaaat ctacaaagtc tttctagaaa aatcactctg
    16921 ctttcctttt gatgtttcta tgataggtgt acttttcact acatctatca tgacatctat
    16981 atctttgagt attggcatat atggtataac cacagtactt ttttctaaat tggtcttaga
    17041 tatagcaaca atatcaacct catctacatc tctatctatc cccatatgaa taaatagatt
    17101 atgtattata gcttgtcttt gccctatatc atttactatt ccaaatgcac ctaaatctct
    17161 tggtataact tctatggcca gacattcatt tctatacttt tctcttgtac tttctagacc
    17221 tatgttagtt attattacac catttaccat taaaataggt ccttcaaaac ttatttttgc
    17281 aggaactata tctgctatat ctgctatact gttccttctt aaaaatcttc taaaaatcaa
    17341 accaacaata gctcctgaca caatagctag gattgtgcaa taaaaaaagc taaggccata
    17401 ctttcttgca aaaacgatat aaactatcga agataccagt gcagaaaaaa gacttatata
    17461 acttctagat tcatacgtag atgctatttc ttcaacgtaa gcgtctcctt ttggtactaa
    17521 ttcttcatta tcgatattct ttagtgttat tctttcttgt tctgcaagac cttgaaactg
    17581 ttgtattgct actgcaaaaa atgtcaaggc tgcaaactcc ttatctataa gtgcaggtaa
    17641 tgctatagca cctaacgaag ctgaaagccc agatataatt atctgttcta aataatcttg
    17701 tggtcttgat gggtattgtt tgtctgtaac tcttaaaact aatcctctac ataatattcc
    17761 tacaactaat gcaactataa aagagtgtct aaataaattt gcattcaata aactttcttc
    17821 cattttctca gctccttctc ttatatagtt tgtgcaaaaa acaaaaaaaa ttcccttcta
    17881 tttaaggaaa tttttttgta atattgtaac tataaattcg ctaccaatgc caagttcact
    17941 ttttactttt atacatccat ttagtgattt gactatatgc tttgttatag ccaatcctaa
    18001 acccgttcct cctacatccc tacttcttgc tttatctacc ctataaaatc gttcaaatat
    18061 gcgttctaca tcttcttttg gtatccctac accattgtct ataactttaa ttacgatttt
    18121 ttcttcatct tttaacacta caacttgtac aatcccatta tcttgggtat actttatagc
    18181 attatcaact aggtttaaga acacttgctt tatatagtct ttattggata gtatacttat
    18241 tgatttatca tcacatttat ataaaacttc tatatttttt tcactagctg aatgttgagt
    18301 tatttcatat acctctttaa atacatcata tactacaaca ttttccataa gaagagtatc
    18361 tttattttct acaaatgata acagcaatat atcatcaatc aaccttttta atctatctga
    18421 ttcgctttct attatttcta agaatctatt tctagtattc acatctatat tttcatttga
    18481 ctttagtgtt tcaacaaacc cacttataga tgtaagtggt gttttaagtt catgacttac
    18541 atttgcaaca aaatcacttc tcatattttc aagtttaact tttttagtaa tatcttctat
    18601 atttactatc gaacctatta ttacgttgtt agtattctga agataaactg ggtctacttt
    18661 tatcttatat acgatatcat ctttagtagt aatattagca gtttcattat ctttagaacc
    18721 aataaattga agtatttgtt ttaatatttc ttcttctttt attacaacat taatattatg
    18781 accttcaact aattgatttg gttcactctt tatcatttct tttgcttcat catttatcag
    18841 aagtatattt ccatttacat ctatagccaa aattccatga gatatactct ttaatataga
    18901 ccttaactgt aaatgtttat actgtacttc ttctaaggtt ttatccatat tctttatcat
    18961 atgattaaaa tttctagcta attcgccaag ttctcctttg gctgatatgt taagcctagc
    19021 atgatattca ttattactta ctttttttga gacgtatata aactctttta aatatttcct
    19081 taatgttatt gtgtatctta cagctaatat aacaatggct atggacaaca taacaataaa
    19141 aaaatatata ctatttaaat cttccacaag ataacactcc taaaatataa cctttttaat
    19201 ctattttgta tcctacacct cttatagtct ctatatattt ttccgattta tcttcatctt
    19261 ctattttttt tcttaaatat cttatatgaa catctactgt tctagtttct ccatagtatt
    19321 cataccccca tattttatcc aaaagataat ttcttgaaag tacttttcct ttattttgaa
    19381 ttaataattt taacaattca aattccttaa gagttaactc tatcttttca gagcctttgg
    19441 taacttcatg ttttgataaa tctagtttta aattacctgt agtaagtata ttgttttctt
    19501 cacctaagct agtcaaatta tatctcctta aaacagaact aatcctagct aacaactctt
    19561 ttatactaaa tggcttagtt atatagtcat cagcacctat ttcaagccct tcaaccttgt
    19621 cattttccat atttttagca gtaagcatta taacaggaat attttttaag tccttatcac
    19681 ttcttatttt tctcaaaact tctattccac ttatatttgg taacatccaa tctaaaagta
    19741 ttaaatctgg tttaatttcc ttagccttta taaatccgtc aaatccatca tatgaataac
    19801 taacttcgta atttgacacc tccaaattga attttaatag ctcaactata tgcatttcat
    19861 cgtctataac aagcacttta gtattcatta aaaagctcct ctctatttta tctgtagtac
    19921 cgttcctatt cgttctgatg ccttattatg ttttctataa gagtggaatt tatctgctct
    19981 acaactagtg cataaattta aatttattat attttctttt ttaactccac tacatctaag
    20041 catatactca ttaattttcc ataaatctaa atagtaactt ccctctttta ttatatagaa
    20101 cttttcatca ttatttgtaa gaattgtgtt aaatttttct actaaatctt cagacacttc
    20161 ataacaacat ggtccaattg atggcccaat tatacatact aaatcttcag gaactgtttt
    20221 atagcattca gacattaatt ttattgtttt atgacctata ttactaaaag tccctctcca
    20281 acctgcatga gccagtccta tggctttatt tttagcatct ataattgata taggtacaca
    20341 gtctgctgta aacagtaaaa gtggtacttt ttccaagttt gttataagtg catctccatc
    20401 tcttcttttc cctatagtat ctttattgac tatattaact atatctgaat gtatttgaga
    20461 attactagtt agattttcaa atgtcaaatc acattcttta catactttta acatatcttc
    20521 tctatttttt gcatctatat tcttacatgt tataactaga tttacagaat ttaatttttc
    20581 atcaagttct tcacaattac cacttaaatt aacatactct ttaatatctt gtacattttt
    20641 tatatttata taatctttca tcatttgtct cctttttcta tcagtatact tttaagttca
    20701 tttacaaaag tatttatatc tttaaattgt ctatacacag aagcaaatct tacataggca
    20761 acctcatcta actctttcaa tttatccatt accatctcac cgattttttt ggtttcaatt
    20821 tcttctataa aacatttatt tatttcattt tcaatatgta caacaatact ttcaatctcg
    20881 tcaatagaaa caggtctttt ttcacatgct tttagcaatc catattttat cttttctcta
    20941 tcaaaatatt ctctactatt atccttttta atgaccatta aaggagttgt ttctattttc
    21001 tcatacgtag taaacctctt tttacatgat tcacactcac gtcttcttct gatagatttt
    21061 aaatctgtat gtctagaatc tattaccttt gattctttat aattacaata aggacattgc
    21121 atctatattc ctcctttgtt taactatatc tcaaactcat ctaagcttaa ttctgaacct
    21181 atatttacta ttattgtatc acaacctatt ttaagtatat cattccaaaa tataacttct
    21241 tcatcccctc ctcttgaaaa aaaacttcta cttccatctc caaaaatggt aaatgagact
    21301 accttacctt cgtgaatatc catgtctatg tctattataa accccatcct ttttccattt
    21361 tttacattta taatttcttt ttccattata tcagaaactc taatcatatt gtactcaccc
    21421 tttctttaaa aataaatatg tatcgaagta aaaaaaaatg acctatatag gtcatttaaa
    21481 ttaaaataat gtttacagtc catggattac ttatacatat tttctcatat tttttaaagc
    21541 atttttttca attcttgata cttgtgcttg agatataccg atttcatcag caacttctat
    21601 ctgagttctt cctttgtaaa accttaaatc taataccaac ttttctctac tatttaattt
    21661 cttaatagct tctttaagtg atatttcttg caaccaattt tcatcagtat cttttttatc
    21721 ttgaacctga tccataacga atattgcatc tccattgtct tgatatactg ggtcaaacag
    21781 agatattggg tcttgtatgg catcaagtgc cattacaact gattctactt ctaattctaa
    21841 ttcctttgct atttctgata ctgtaggttc tttagaattt gttctaatta atctttctct
    21901 aacttgtagt gccttatatg ctatatcttt taatgaccta cttactctaa ttgggttatt
    21961 gtctcttaga taccttctaa tttctcctat aatcatagga acagcataag ttgaaaacct
    22021 tacattttgg cttaaatcaa agttatctat agcttttata agaccaatac aacctatttg
    22081 aaataaatcg tctatatttt ctcctctgtt gttaaacttt tttattacac tcaagactaa
    22141 tcttaaattc cctcttacaa actgttgtct ggcttcttca tcaccatttt ttatttgtaa
    22201 taaaagttcc ttcatttgct tatttttaag aactggaagt tctgatgtat taacaccaca
    22261 tatttcaacc ttattaactt gcatatattt tcagtcctct ctcaaaagta ttcatctatt
    22321 gaaattattt acatttccaa tttttttata ctttttaaga agaattaatt tagcattata
    22381 caaatttttt catttctttt tgcaaccttg agattatttt cttttcaagt ctagatatgt
    22441 aggactgtga tattccaagc attccagcaa cttctttttg tgttttttca atacctttat
    22501 caataagacc aaatcttaat tccataattt gcttttctct gtcacttaat ctgtcaagtg
    22561 ccataaccaa caaatctcta tctatttctt cttcaattat tttgtatatt tcatcatttt
    22621 ctgtacccaa tacatcagat aataaaagtt cgtttccatc taaatctata tttaaaggtt
    22681 catcaaatga tacttctgtt ttctttttat tattttttct taagtacatt aatatttcat
    22741 tttctataca tctcgaagca taagttgcca attttatatt tttattcagt ttaaaagtat
    22801 taactgcttt tatcaaacct atagttccta ttgaaatcaa atcttctaca tctatacctg
    22861 tattttcaaa ttttctcgat atgtagacta ctaatctaag atttctttct attaaaattg
    22921 actttacact ttcatctgtt tctagctttt gtaaaagctc catttcttct tctggtttca
    22981 atggaggagg aagtatattt gcccctccca tatagtatat tccctttggc tttattattt
    23041 ttaatttaat acctaacata gtaataaagc ttattattct ttctttcaat cgtaacattc
    23101 cttgtccccc ttaaattttc acctaaaatc caggcaatat atttggattc attattgctc
    23161 catattctct atcattaaaa tttgaaatac caagtattat atttcctatc ttttgctcat
    23221 ctacttctat atagtcagct tttaagccta ttattatgct tgtcttatta cttccagcat
    23281 gtttataagg tattattcta actctacctg aagttttatc atctaaactt cctataattt
    23341 cttgtgcttt cttcatatct atatcttcat aattaatatt taatagtttt tctggaataa
    23401 atccttctaa cacactagac ttaactatta ttacatcact ttgacttatt gggtctttta
    23461 acaaattacc actatctact aaagccttac agcaaaaact tttttctagt aagtttatat
    23521 ttatagtctt tgtaagctcc ttaatgtact taagcatttt caaatcttta taaatgtatt
    23581 ttaataattc acaactcaca taagtacatg caattaagaa agatattttt aagtgactta
    23641 ttcctgtaaa ataaattata aaataagtgc ttccagaaat aaaaatgttt actagataaa
    23701 aaactaacgc tacatgaaca taatcttttt tgctcttact tctaaatgaa attaaagtta
    23761 ttatactcat gattattatt ttaaatggta cagtaaatag tatattcatt gatggataca
    23821 aataagcaac agaataggca cctcctaaac tagcccccaa taacttattt tttttaggat
    23881 tatatctttt agtaagaata gaagtacaac ttataataat ataatttatt actaggtttt
    23941 ctataacata gtactcaata tacaccatgt atcccccctt aaaaccttta aacatattat
    24001 aagatagtat gtacaaaatt ttatgtcact tttgatggtc gaatccaaaa caaattctat
    24061 ttaaaaagaa caatgatata tgtcttatac tttatgtcgt caaaagatat ttttttaata
    24121 ccaaacaaat agactttttt gtagaatcca atatatctag gtagaagtta ttcactctac
    24181 ttttggtata tttacaaaaa aagactacat aatttaataa tatatcaagt aaatctttta
    24241 cttatataaa atcaaattat atagtctgta aattcaaata taaattattg tgctagtaat
    24301 ccatttgcat attttgcaga ttcatttagt gcttgttctg gagttatgtc tccagctatc
    24361 atcatttgaa gttgtttcca taaatattca tatatctcta ctccatgagg tccaactgtc
    24421 aatggtctat acatatgttt atctcttgtc accatttctt caaatcttgg gtctccttgg
    24481 tatttttcac ctttagcaac tggagctcta ggtatttctt tgtggaaagc ttccattgat
    24541 tctttgctta gcatatactc aagaagttta aatccaagtt ctttattttt acatgctgac
    24601 attaatgtta aatcatctac tgaagcaaaa cttccaactg tcttatcttc taatgatgtt
    24661 acatatcccc agtttaaatc cgggaatgat ttatcaaaag tacttgtagc agcagaggat
    24721 agcattatag taaatgcagc ttttcctggt ccaaatacac tttcaatcat ttcattacta
    24781 tcttttgata aagcatcttc tggaatatac tttttcatat catttataaa gtttgcagct
    24841 ttcaagcctt ctgcattatt aaatttaact gattttaaat catcattata tatatctcca
    24901 ccagcttgcc ataaatacgg ataccagttc cagtttaagc ttccaaatac tttagaaccc
    24961 caaccttgtg caagacccca ctggtcgatt tttccatctc catcagtatc ttttgttgct
    25021 ttttcacaga ttcttttaaa atcatcccat gtttttggag gtttttctcc taatttttct
    25081 agtatatctt tattgtagta caatacgcct ggattagcag cttctatagg taaaccataa
    25141 ataccaccca tcatttttgc atcatctaag tatagataat tatctgaagt tcctgatttt
    25201 tctaaataag gtgttaaatc ttctaccgca cccatttcta taaattgagg aaacatctct
    25261 gcatacatgt atcctatatc tggaccttca cctgcactta ttgctgttgc atatttttct
    25321 gcgtagttat cccatggtac tatctgaaat tcaatttcac agttattttc tttttcaaat
    25381 ttttcaaata tcggcttcca tgcatctgca tcatggtctg ttaatggtgc agaccataca
    25441 actaattttt ctttaccctc tttgccttta gaatcttctt tttttgaaca tcctgcaaga
    25501 attgatactg atagaatccc taccataact aaagaaagaa ccttttttag tttaatcatg
    25561 cttaatcccc tttcagactt taatttgtct ttttcctcaa atgtttacat ttaattcaga
    25621 tttaatatta acaaataaga ttactcttgt ctaatcataa aaaactatac taactcctat
    25681 aactatattt tttttctata cctattagat ttaattcata ctaaaaactt actttttaaa
    25741 ttttatcaat atttaaaaat ttttttaagt ctagccacaa actaactatc taaattgagc
    25801 aaaataaaaa gaagtctatt gacttcttta taagcttaca tattatcttc ttcttcttag
    25861 gaatgtaggt atctccatgc tctcatcatc atcttcttca attatacttg cctttttagg
    25921 aggctctatt ttttcctcag caattacttc ttcttcaatt tcttttacag cttgttttac
    25981 tgttgtattt aatgaagaac gtatgcttga tttaggttta gtatctaaat ctaaggcacc
    26041 attttgtaat ccttcaaatc ctgtcgcgat tactgtaatc attatttcat cacctaaatc
    26101 ttcttttata gaagctccaa atataacatt tgcttctggg tcacaggatt ccataactaa
    26161 agttgatgcc tcattaactt caaataatcc taagttagga ccacctgtaa cattaagaag
    26221 tactccttta gctccttgta ttgatgtttc tagaagtgga gattgaatag cttgtcttgc
    26281 agcatcaatt gctctagttt caccactagc actacctata cccatatgag caagtccctt
    26341 gtctttcatt atagtagtaa catctgcaaa gtccaagttt attaaccctt caactgctat
    26401 aaggtctgaa attgattgta taccttgttt taatacatca tctgcaactg caaaagcatc
    26461 taacattgat gtattttttt gtactatctg taaaagtcta tcatttggta tcgttataag
    26521 agtatctact tttgatttaa gttctgctat tccaccttca gcgttcttca ttcttatctt
    26581 accttcaaat gcaaaaggtt tggtaactac acctactgta agtatcccca tttcttttgc
    26641 caagcctgca accactggag cagctcctgt accagtacca ccgcccattc cggctgttac
    26701 aaagaccata tcagctcctt gaagtaactt tactatttca tctttactct cctcagcagc
    26761 tcttttccct acttctggat ttgctcctgc tccaagtcct ctagttaatt tttctcctat
    26821 ttgaacttta tattcagctt ttgatgtata taaagcttgt ttatctgtat ttactgatat
    26881 aaattcaacg ccttttagtt gagcttctac cattctattg acagcattgt ttccaccgcc
    26941 acctacacct attactttaa tttgtgcaca ttcttctaat tctacgtcaa agtttagcat
    27001 cataaacccc cttctctcat gattcaaagt tatcgtatgt attaattata tcattttctt
    27061 cttttatttt gttaaccttt aagtaacata ttccacaaaa acgtaaattt tcctttttaa
    27121 atttcttact tatattgtca aatattactc tttaagtata aaataattta cgtatatatt
    27181 aaatgctctt taatttttac gttttttgtt cataatatta ctaataatat atcgtctaat
    27241 tatagataag ttattaaaca atctcatacc aaaaactaat acagcaacat agtaaagaga
    27301 aactcctaac ttttctccta tataagtcaa taatatagcc aatatagcat tacctatgaa
    27361 accagtaata aaaattacat tatcatagtt atcttcaaaa ttggatttta tcgctccaaa
    27421 aatagaatcc attattgcaa gaatagctac tgacatatat atggaataat ccatagaata
    27481 tgtaaatgga atatagtaac ctactactac accaaatgct aatcctccta aaacccataa
    27541 cataaatctt cacctcttta ttttactttg aaacacaact acattacaat cctttttatt
    27601 aatttttttt actttttctt tatttttttg tatttttcgt tttattttgc aaataaatcc
    27661 actttatttc cattattttc ctgaactttt atattaattc catatatatc cttaagagat
    27721 ttagcatatg attctggaga gtttatagct gcactcaata aatctatatc tcctatagct
    27781 tttattataa atggttgtcc atatgtagta tcatttactg taatagtagc tcctgaacat
    27841 tttatcttac ttgttgctag tactctttct ccatttatag aaattgctct tgctccagcc
    27901 ttttttaaat catttaaaac cctcaaaata tctatatcat gtataatcaa atcgtttgga
    27961 ttctgtccgt cttttaactc tctctcacta tccctcatag taatagttat gcctggccct
    28021 gtaacagttg aataaccact taattcttta acttcttcaa gctctttttg cataagtgtt
    28081 tggatagatt catttccatt cttttttgct tctttatatt cattcaaagt ttttttgttg
    28141 tttttaagag tttcttttaa attttttatt tctttttttg tattttctac ctcactttca
    28201 atactttcag tttgacctaa tgttatgtat actctatttg ggtctagtga ttttatataa
    28261 gttgatatga aaacgcctaa tatgaatgct cctaatataa ctattttctt tttcatacta
    28321 ttatttcccc tctgctttgt ttatatcact atgaccattt atttctatat tgtcttcttt
    28381 ggtcactttt actttggcat tataatatgt ttctatttcc cagacaatac catactttat
    28441 attaagtgcc gaagccaatg tatcagaatc accaattgct tttattataa ttggttcttt
    28501 tatgacagtg tcattcatat aaagcttgtc ttcttttaaa tacatatatg tattagaaac
    28561 tattctctgg tcgtttatag atatggcact tgcttgtgct gaatttaatt tatttatcat
    28621 tgacaataat aaatcataat tatatagtat actatcattt ttatcagagt ttcctaagtc
    28681 ttttgtagaa tttatctcaa tttttatgcc tgttccttca acatctgtat atccagctaa
    28741 tgtttcatat ttttctattt ctgacttaag tatgtcttgt tctccttcat tgtttttgcc
    28801 tctataagtc tctatatctt tcttcacact attaacttct gattgtagat tctctttttc
    28861 tttttttaaa gatttaagtt cttctgtaag ttgctctcct cttttaaaag ttgtcatccc
    28921 tctattttct atattaataa ttttaagttg taaactaaca agaacaccca atacaatact
    28981 tcctatgatt atacttttat ttataaatct ttttttcaat atatcacttc cttacaattg
    29041 tctatccttc tggactatac actgccaact ttccatagtt aagatttata gtccctccat
    29101 tagtattttt attttgcagg tcaatcagaa ttttacttac cctagatata ttataatcta
    29161 agttatcatc attagaaagt aagattttta tattacttct tgtaagcatt tctatattgc
    29221 tttctttttt taagtttaca taatttattt ttctataaat tccttcttct tttaaataat
    29281 ttaaagtttt aaatacattc tccttagttt tataattttt aaattttata gatttattat
    29341 catcaatgct ataatctaca tctactatca agtctttttt actttcatta gaacctctta
    29401 gttcttccaa taaatttcct tttttatcta tataacaata attatcttca tcttttaata
    29461 ctgcaaatat ttctttttct tttaaactta taattatctt attgggaagt tttcttttta
    29521 tttccacatt ttctatatat ggatttttta taagtttatt tttcatatct ttaaaattgt
    29581 atgcaaaaat attttcattt agatttacat ttagttcttt cattatattt gatttggtca
    29641 ccctcttatt tccaattaca tctattttct ttacatcaaa taaatcactt tttacaatta
    29701 tacatataca aaaagataac ataagtataa aaactaaaac tatcatgaca ttattcgtat
    29761 ttaactttct tctttttttc aaatataatc aacccctttg gttaataaat acacctttag
    29821 agcttgtttt tcctacaaaa aaattataat atttaaagtc aaatttttgc attttattac
    29881 ataacatcca aataaggtat taaattttat aaataaatca atatttcatc aaaataaaca
    29941 tagcatacta catactattt atatatttaa atctgtatac atacaaataa acccctaatt
    30001 tataataatt tagaaaatct aatatattat aaattagggg taaatattta cttatctttt
    30061 ctttattcct attaccttag cttgaccttc tatacttgga gtcgtttctt tttttatttc
    30121 ttttacttcc ttaataactt tttctttttt tgttttttta gaagttgact tttgtgttga
    30181 attgtatact ttcattatct catcatatat aaggtctatg gcttcaggct tacctatagt
    30241 tttacttgca tttgccatat caaccaaaag ttctctatct cctaaaagtt taaatactgc
    30301 tgtatttagg ctctctggag ttagattttt ttctaaaata gcaattcctg ccccttgttt
    30361 ttctatactc ttggcattat actcttgatg attttcagca gtataagctt taggtattat
    30421 tatagatggc tttccaagag ccgttatctc agctaatgaa attgctcctg cgctacctat
    30481 aaccaaatca cttgctgcaa gtgcatttgc catatcttct aagtaaggca caactttttg
    30541 gtatggttta agatttatat cgctaatact tcccataaat tcatcataat agcttttgcc
    30601 tgtagcaaat ataaaagcta tatcttcatt taccatattc tttattacaa gtctcattgc
    30661 atcatttatt tttcttgaac ctccactacc accatagcaa agtaccattc ttttttcgtc
    30721 acttattgat agattctttc ttgcaatatt ttttcttgat aataaaattt cttttctaac
    30781 tggatttcct gtaaaaacta atttatcttc tgctgcctct ggaaatcttt tatgcgaatc
    30841 ttcaaaactt gtaagtacct ttgtaactgt tttagataaa atcttattag ttacaccagg
    30901 aaaagaattt tgctcatgta ttatggctgg tattttcccc atagatgcat taaataaaac
    30961 aggtccacta acatatccac cagttcctat aactatatct ggtttaaatt tcttaacaat
    31021 ctttcttgat tgctccaaac ctttaaaaag cttaaaaact ctttttacat tatcgaaatc
    31081 tatttttcgc ttaaaacctt gaactgttac agtctttaat tcaaatccat acttaggaac
    31141 tatttctgac tctattccct tttccgtccc aacaaaaatt atctcagcgt ctggatgctc
    31201 atctcttatt ttgtttgcaa tagctatagc tggatacacg tgccctccag ttccaccgcc
    31261 tgataataaa actttcatca aatcatcatc tcctgttaat taattttgac atgctttgag
    31321 atgtttaaca ctattcctac agctcccata aagatggtga gtgaagttcc tccataactt
    31381 ataaatggta gtgctacacc tgtagctggc attgatgatg tcgcaactgc tatatttaaa
    31441 gctgcttgta ttccaatttg tgcacctata cctataacaa ccatacaagc aaatacatta
    31501 gaagtcttca aagctattct tacacatctg tagactaaaa ctacaaatag cataataact
    31561 attatacaac caatcaatcc taactcttct cctattatag caaatataaa gtcattttgt
    31621 ggctctggta tataaaaata cttttgttta ctctttccta agcctagacc aaacaatcca
    31681 cctgaaccta gtgcatatag accttgtatt acctgatacc ccttaccaag agggtcttga
    31741 aaagggtcta aaaatgatgt aacacgacta agtctatagg gttcagcaat tactaatgca
    31801 gcaaataaag cagccccact ccctatcata gcaaatacaa ttttcatatc cattccagca
    31861 acaaatatca ttacaaaagt aactagaatt acagtacctg ctgttgacaa atttggctga
    31921 agtattatca acgcaaaaaa tatccctgga actacgagaa gtggtacaac accttttgtc
    31981 aaagatttta ttttatcata atttttttca attaattttg cagttaatat tattgtagca
    32041 aactttgcga tttctgcagg ttgaaatgtt aaagctccta ttcccaacca tctttttgct
    32101 ccgtttgctt ctatccctaa aggggtcaaa actaacaata ataatactac tgctatagct
    32161 ccaattgctg tagcattttt cttccaaaaa ctataatcta ttcttgatgt aataatcata
    32221 actataaatc caagtacagc atatattaca ttctttttta gaaaatagta cgcatcattg
    32281 tgtttaaatg aagattgtat aaaacttgca ctaaacacca taactattcc tacaaatact
    32341 aaaagcatag tagtgtaaaa cactactcca tcaaattcag tcttcaccct tatgtcaatt
    32401 tgttttttca aattttcttt aggcatccaa ctaatctacc tccattcttc catttaagta
    32461 agtttagagg taagagatta ttttaaattg tttacattat ctttgaagtc ttttcctctt
    32521 acttcaaaac tttcatacat atcccaactt gcacaagctg gtgaaagaag cactatatct
    32581 ccactttttg aaatttcata agaagtctta actgcttctt ccatatcttt tactatatgt
    32641 atgtcattaa atcctttatt tttagcacaa ttttctatat ttgatgcagt ttctcctaat
    32701 aagaccaatg atttaacata tgactttgca gtttcaagaa gttcatcaaa attacttccc
    32761 ttatccatcc cccctgctat aagtattata ggtctatcat aagactgtat agcttttata
    32821 gtggaatctg gattagttcc ctttgaatca tttacatata ttacattgtc taaatttctt
    32881 acaaactctt gtctgtgttc cactccttta aatgtcataa gtacatcctt tataacttct
    32941 aaatcaattt tgcagacata tgctattgct atagctgcca tacaattttc taagttatga
    33001 cctccaggta aacttacatc atctttattt agaaatttga ttttatcatc tatatctatt
    33061 attatgtcat tattttctaa atatactcct ccatttactt ttttagttct tgaaaagtaa
    33121 attactttgg cattgcattt atcagctaaa gattttacta tctcatcatc atagtttaat
    33181 acacagaaat cctcaacagt ttggttcata aatatatttg cctttgcttc tatgtatttt
    33241 tccatagtat ggtgtctatt taaatggtcc tctgtaatat ttaatattgc gcttacttta
    33301 ggtctaaatt catctatact ctcaagctga aaactgctta gttcagttac taacacagac
    33361 tcttcacttg aagtttctat agtatctatt acaggatttc ctatattacc aactacatat
    33421 gtatctcgtt ttgctcttga aaaaatttct cctaccaaac tagttgtagt tgtctttcca
    33481 tttgtacctg taatccctat aaaaattgga ttatccgata gtttaaaagc taattctacc
    33541 tcaccaatta tatacttgcc tgaatttttt aatttcaata tgaatggtag gtctagtggt
    33601 acacctggag acactacaac catatctata tcatctacat cttctgggtg atgtcctaat
    33661 atgtatttta tgtcatttat agatttcaat tcatcaagta tatttctcaa tttattttca
    33721 tcttttatat catttacgat tatacttgca cccaatttat ctaaatgttt aattgtagat
    33781 ataccagttt ttgcaagtcc tactaataaa actttttttc cttttaagtc catttttcat
    33841 tccccctagc cctaaaatac tgctattata cttatccaag ctaaaacaac tgttataatc
    33901 caaaaaataa atacaactct tgtttctggc caaccacact gttcaaagtg gtggtgtatt
    33961 ggagccatct taaagaatct ctttcttgtt gccttaaaat atccaacttg aatcaaaact
    34021 gatagagcct ccgcaaaata aattcctcca attataggta ttataagcac tgagttagtt
    34081 agaactgaaa atgctacaac tgcacctcct aatgccattg aacctgtgtc gcccataaac
    34141 actctagccg gatatgaatt aaatcctaag aaacctaaac atgctccaac agttgctgct
    34201 gctaaaactg cgacttctgt atttccagca atagaacttg caaatagcat aaagaataca
    34261 gaaactatta atgttactcc tgatgctaat ccatctaatc catcagtcaa gtttacagca
    34321 tttactattg ctacgattat aaacatcatt attggtatat ataatattcc aacatttatc
    34381 acaaaatctg taaatggtat cataagttgt gaagcacttg atgatgatgt atactgataa
    34441 aaagcaacat aaaaagataa tgcaacttga aggattattt tttgatatgc ttttagtcca
    34501 agtgatcttt ttagctttat ttttataaaa tcatctaaaa agccaataaa accaaaacct
    34561 gcaatacata taagacctac tgccatatca tgactaactt ttactcttgt aagtccagtt
    34621 attagaattg caacaatcat tataattcca cccatagtag gtgttccgtt tttagctaga
    34681 tgtgtttggg gtccatcatc tctaactgtc tgaccaaatt taaattttct aagcattggt
    34741 ataaatattg gtcctattat aattactatt aaaaacgcaa tcaatgcggt gtacgtaagc
    34801 tctgttattc ctaacatcat aaaactcctc tcccttgtca attaactcat tagtttaagc
    34861 ttatttattt agatattcga ctattttttc taatctcatg cctcttgagc cttttactaa
    34921 aatagtgtct cctgttttta ctaattcatt taacttgtta aacacatctt ctctattctc
    34981 aaagtgatat atattggctg aattgaatcc taattgtttt gcttcttctc caataaacac
    35041 tgaattttca cctatagtta ttataatatc agtattattc atagatgatt ttccaactaa
    35101 tctatgacca tactctgaaa tttcacccat ttctagtata tctccaagta tcgctaccct
    35161 tctaccttta tatcttccaa gtatctttaa agcagcatcc atagaatctg gactagcatt
    35221 atatgaatca ttaattattg ttaatttttc attttttatt atgtctagtc tcatttttgt
    35281 ccctttaaaa ttttttaaac ctttttttat ataatctaaa gaaatattta gacacaaacc
    35341 aactaatata gcagacattg cattatatat attatgttct cctattgttg gtataaatat
    35401 ttcctctttt ttcccatcta ttacacatat aaatgttaaa ctatcctctt ccatagtata
    35461 actttcacaa taaacatcat tgtttttatt aaagccaaat gtttttaact tatatacatg
    35521 ttctttttct tttaatgtag ataaaaactt atcatctcca tttacaatta aagtatttgt
    35581 ttcatcaaag tttgaagtaa tctccatctt tgctttcaaa ataccctctt gtgaacctag
    35641 tttttctaca tgtgataatc ctatattcga tatgactgca attttaggat ttactatatc
    35701 cactaaatat tttatttcat tgaatccaga catacccatc tctattacag cacactcatg
    35761 ttctttattt agattaaata aagtcaatgg aactccaaaa tgattattta agtttttttc
    35821 attttttagt atatttaact ttgcagatat ggcagagtaa atcatatctc tagtagtagt
    35881 ttttcccaca ctacctgtaa cacctataaa tggaatatca aatttttctt tatagtattt
    35941 tgaaatatct cctagagcca aagatgtatc ttttacctct attaaattta tatccgaact
    36001 ttctaatttt attccattac tttcattttt tataaaagtt ttacatccac tatcatatgc
    36061 agacttcata aatgtatgcc catctaaatt ttctccaact atggctacaa atgcattttg
    36121 ggcatttgcc tccctgctat ctataactat atcacttaca cagtcattat aatctccata
    36181 tattaacttc ccattagttg caagtactaa ctcttttatt gttaagcact ccattattaa
    36241 actcctcctt taaaacctta gctatattct cttagcaaca aaaggcaatg tataccgtta
    36301 tatatacatt gcctacgata actcttaact ttataattat atactatatt tctgtttttt
    36361 tgaagatgtt tatgggtata tgttaattat ctgttacttt ttagttttca aaatataggg
    36421 ttatacttga gtcttcatta acttttactc caggttttgg gaatatatcc tttacctttg
    36481 tatcttctgg aagttctata tctgcatcta agtctggttt taacttcgca tcctccaatg
    36541 cctttacagc atctcctatt tttagatttc ttacatctgg cactttaact tgcttctttt
    36601 catactcagc tttttcttct tctttatata ctggtttaac tcccaaatat tttaaagagt
    36661 cattcattat ttctttcact attggtcctg ctgtagtact accaaatgca cttactcctg
    36721 ttggttcgtc aacaatagca agaactacta tttgcgggtc atcacaaggt gctattccaa
    36781 caaatgaaca tatatacttt cctggagcat acttaccatc tataactttt tgagctgtac
    36841 ctgttttacc accaagtcta taacctggta tatacgctat ctttcctcca ccttcagtta
    36901 caactgattc tgcaatttct aacatttttt tagatgtttc tttagatata acacttctta
    36961 ctttttttgg ttttactgtt tcagttatat ttcctttatt gtcagtataa gattttacca
    37021 ctcttggttg cattaaatct ccaccattag ctattgatga tatagctgtt ataagttgta
    37081 ttggagttac tgatatagat tgaccaaatg atattgtagc caattcaact ggtcctacat
    37141 ttttttcgtt atacagtatt cccttagctt ctcctggtaa atctatacct gtcttatcca
    37201 taagaccaaa tgattctata taatcataca tttttccaac acctaatctg cttcctaact
    37261 caacaaatac tgggttgcaa gagttttgta ctgcttgttt aaattcttgt gttccatgag
    37321 gtctgtaatg tctccaacat ttaatctttc ttcctccaac agttacacta cctgtacatg
    37381 tgaatttttc tccatcttta attactcctt cttcaagagc actggaagat gtaataagct
    37441 taaatgtaga acctggttca tatgtatcac ttactgctgg atttctccac atttgataat
    37501 agccttttat tttatcttta tcattatatt tttcaagttc ttcttgataa tatggatata
    37561 ttggcgtcct tgagtcatta gggtcataat ctggttttga tgctaaagca agtatatcac
    37621 ctgttttagg gttcatagct attgcagtaa ccttttttgc attatttaac tcataagctt
    37681 tctgtactgc tttttcagta tagtgttgaa ttacttcatc tatagacaac acaagaccat
    37741 taccttgtac aggctcataa tatttttcca ttccttgtgg tatttctctt cctgaagcat
    37801 cagtacttac tataagtttt ccaggctttc cttttaactt tttatcatat tgcatttcta
    37861 caccagatat acctgttgca tctgaagaag tatgtcctaa cacatatggt gcaaaattcc
    37921 catatgggta atatctttga ttatcttctg ccacccatat tccacttaat ttagcatctc
    37981 ttatttgact tgccttatca tcatctatcc atctttttac ttttacaaga gccatatttt
    38041 ttttgcttat taaagcgtaa atatctttat aatcttcatc caaaatctca gctacctttt
    38101 cggctgcttc ttttttatct tctacttcca caggtttaca ccaaacagta tacttagtta
    38161 cacttactgc taactctttc atatttctat catatatagt tcctcttttg ggttctattg
    38221 gtatatctct tgtttgttgt tctagtgctt ttgtactcaa ccaatttccc ttcataagtt
    38281 gtagataccc agtcctaata acaaggcaaa aaaacaatgc acatgctaga ataagaacga
    38341 gtaccagcct tttcttactt atcctcttta cttttctcaa atctattccc cctagttatc
    38401 cacatctata tactttattt gtccatcttt tggatagtcc atattgagca attccttagc
    38461 ctttagctca atttctttta ttgatgtttt ttcagtttct tttgccttta gttcctctaa
    38521 tactatctct ttttttctta aatctttttg taaataatag atatcgtact tcatttccga
    38581 gatttttgaa taaccacata gattcaatat tattactgaa aaagttgcaa tcagtaaaat
    38641 gcatttagct cctatttttt tcttatttct ctttttataa ttattctttt ttttattttt
    38701 atattcattt agattatgta ttttataatt ttttttcaaa ttctcacccc gatagtatat
    38761 agtttaaatt ttcctctata ctatatttgt tattaatcat atttcttcct ctaaaatttc
    38821 atcgctaaat taatacacta ttacacaatc taattgtatt tttttctata cacaacaaaa
    38881 acctataaat tcacttatac ttttatatga atctataggt tagatattaa tttctattta
    38941 tttttatcac ttctagtatt tttagataat ttcttccata aatataatat gtaactaact
    39001 atctactctc tgattcctaa gttctccatt atattactta ataccatcta tatctatatt
    39061 tttatatcta aattttcatt atatatctca ataacaaaga acatttctta tagtgttaat
    39121 tgttttttaa ttgctttacc agtgcaacaa aatatataat actttttaat taattataat
    39181 aatcttatat ataagattat tctttagcct tataactact tatatttttt ctgctactct
    39241 tagcttagca cttcttgaac gtggatttac ttctatttct tcctcactag gtaatatagg
    39301 ttttctagtt attattttca cctcagattc tttatcacat tggcatatag gtaaatgctg
    39361 tggacatata caatctgatg ctaaatgctt aaatgcattt ttcactattc tatcttctaa
    39421 tgaatggaat gttattatac atattcttcc accttcattc attatagaag aagcatcatt
    39481 tatcatcttt gtaattactc caagttcatt atttacttct attcgtattg cctgaaaagt
    39541 tcttttagct gggtgaggtc catctattct ggctttctta gggatagctt ttttaattac
    39601 atctactaat tctcctgtag tttctattgg tttgtttgct ctttcttcaa ctataaattt
    39661 agctatacgc ttagcccagt tatcttctcc ataatctttt attatcttag ttaattcatc
    39721 ttctgtataa gtatttacaa catcatatgc agaaaactca cacctaacat ccattctcat
    39781 atcaagtggt gcatcttgca tataagaaaa tcctctatca gcttcatcaa gttgatgaga
    39841 tgaaactcct aaatcagcta atacaccatc aattttgtaa actcctattt tttctaattc
    39901 ctcttttata ttttcaaaat tgctgtgaac aaacttcact ctactttcat attcactcaa
    39961 tctctctttt gctgtgctta tagcattttt atcttggtca aaccctataa ataatccctt
    40021 atctgacagt ttttttacta tttctttaga atgtcctgct cctcccatag tacagtcaac
    40081 atacacgcca tctggcttta tatttaaatt ctctatacac tcatttaaaa gaactgatac
    40141 atgatgaaat tccatagtta cctcccttaa attcactttt taaactattc ttcactaata
    40201 ttatttttat ttttctttga taaataaaca tgtgcaatta tgccaccaat aactccaatt
    40261 agacttataa cttgtgccat tctaagtggt cctaacatta aactatctgt tcttaatccc
    40321 tctataaaaa atcttcctat tgaatataaa gttatataag taactataac ttgaccttca
    40381 tattttttat tttttctaaa tagtaataaa actataaata ttccaaaatc ccatatagac
    40441 tcatataaaa aagttggatg tacctttact ccatcaacca ttattcccca aggtaaattg
    40501 gtagcacctc catgtgcttc tccattaata aaatttcccc atcttccaat agcttgtgct
    40561 aaaggcattc caagtataac tgtatcagcc atttttaaga agttaatatt tttaatctta
    40621 gtgtatatat aaccagctaa tattccacca attaaccctc catgtatagc aagtccacca
    40681 cctctaaaat taaaaatttg agacatattt tgagcatagt aactccaatt aaatacaaca
    40741 taatagattc ttgcacagat tagtccaact ggaattgcta ttatagctat atttaataca
    40801 tcatcttctt taattcccac tctttttgct tcttttattg ctattaaagt tcctaaaatc
    40861 attccacatg ccataagtat tccataccac atgatgtcta tgccaaacag tgtaaatgct
    40921 actctatcca taacgtcacc tctttgtatt aattgaaaat atttccaaag caatatgcta
    40981 taattacaat taattgtaat tatactaaat tatgataaca cattaatgtt aattctacaa
    41041 aaaatattaa aatttattct acaactccct acactatatt atatctaatt actataaaat
    41101 tttttaaact aaatctctca tgactaaagt tacaagtgta catagatatt ttttaatcaa
    41161 aaagattgat gcatatatac atcaacctct tctaattctt atctatagct cttaaatttt
    41221 tacctcaatt tatataaata tattttataa atttgtttta ccaaaataaa catttaaaaa
    41281 cataaactaa tacttaatta gttattctta ttatgattaa gtttctattt aggctctaca
    41341 atagaaataa cacaatactc ttctttaaaa tgctctttta atctttcttc aacttcctca
    41401 aaagtaatat ctttaataat atctaaataa tccaatagat ttatatcctt aaaaacataa
    41461 gatataaaac tattacctat aaagtttata gaatcaaagc acttaataaa tgaccctatt
    41521 tttttctttt tagttctctc aaactcttct tttgataatc cttctttttt tgatttttct
    41581 atataatcaa gaattatttc ttttactttt ttaggctctt tagaatctcc agctattatg
    41641 ctaaaagcat aatccacttg agacgaaaat ccagctccaa aattttcatt tattaaacct
    41701 tgcatataca aatcttcata aagcttactt ccttttttaa ataacatccc tacaagtata
    41761 tcagttacaa tctctttacg taaaagttct ttccctttta aaccaacatt gctatcttta
    41821 aaacctatgt tgaacatagg catagatata gggaattttt ctataacctc tttttctttt
    41881 acactttctg gttcttctgg ataaaatctt tctatactct tagagagtct gtctactttg
    41941 taattgtttg actttttagt tacatctata actttttcta catctaagtc accaacaaca
    42001 aataaagcca tatttcctgg attatagaaa gtattataac atttatatag ctcttcctta
    42061 gttatcttat atatactatc aacagtacct gctatatcaa ttctagcagg ataatttaca
    42121 tacattgcct tcaagcaatt aaagtataca ttccaatcag ggtcatcatt gtacattttt
    42181 atctcttgtg ctattatacc tttttccttt tcaacatttt catctgtaaa ataaggtgtt
    42241 tgaacatagt caattagatg ttctaaactc tcataaaaat tttcagtagc agaaaataag
    42301 taggctgtca ttgtaaaatt agtaaatgca tttgcattta ctcctaattt tgaaaattta
    42361 tcaaatgcat ctcctccatc aggttgctca aacatcttat gctctagaaa atgtgcaata
    42421 ccttcattca ctctaatttt cttatcttct ccaattggta caaattctaa gtcatttgaa
    42481 ccataattag tagccaaaat agcatacttt ttcataaaac cccttttagg cataaaatat
    42541 acatctaatc cattttgcaa tttctcataa taaacttctt ctttcaatat atcattaact
    42601 attttttcca tagacatctc ctccattaat ttctcaagaa gtatacagta tcaagctcta
    42661 tattttttat agcttcaact atatcttttt ttgtaacctt ttctatacta gatattatgt
    42721 cttgtacttc agaatttgtc tttgccatag actgagagaa aacaaaatca gacataccac
    42781 ctatattatc agttatagat ttcatagaat taactaaagc aagtttactg ttttctaatt
    42841 cttcatcaga tatatcacct gcttttacac tttctacttg tttttttatc aattctacag
    42901 ctttatcata atctttagtt tctataccag atgatataaa catgatactt ttatacttct
    42961 ctattgaaga gaatatatag taacataaac tttctttttc tcttacatta acaaataatt
    43021 tagagtgtgg accaccacct aagacattgc tcccaactac taaagcataa tatttatcta
    43081 tgtctgcata atccacattt gctctataac ccataactaa cttaccttga gttatttcca
    43141 tttgttcatc tataactttt acctcatcca cattttttat aaaatctgct cttggtatat
    43201 ttataatttc ttctctttca aattttagat ttttacttat tatatctaca actttatctt
    43261 catcaaaatt accttctaca actatatcta taggtgatgt tttaagtatg tttttataat
    43321 gttcatataa ctctcttgaa gttatactat ctatttcatc ttcataacca aattcactta
    43381 cactatatct ctctccttta cacatagcct caatacattt atcttgcgca tattcctttt
    43441 tatcatttat tattgattgt atcttttctc ttaaattctc tttttcaata tttaaatatt
    43501 cttctttaaa cccaccatct acaacaagcg tattatttat tacttcatta aaaaattcta
    43561 ctacttcttc aaatatactc tcatctaaat acttttcact tatgttaatt actttaaaac
    43621 tcaatacttg acgttctcca cgttttacag catcagctcc catagatgaa ccatataaat
    43681 catctaattt attggatatt gctctagcac taggatattt agcgcttcca cttgctatta
    43741 ttgatggtat tagagcattt tttgtagttt ctttttcatc caatagtctc tgaacatata
    43801 aacttataag attcgattta aacttttctg tttttatcaa agtaagatta atattattac
    43861 ctaaatttat tattttttta gtattaacca tatgtacctc ctatttttat ttaaacatca
    43921 attttaaaat tgaaatttat ttatttttta attacatata ctcacatata aaaaccttct
    43981 atttaattat atccttttta ttattttcta aaagcaatat ttttatttaa attaaataca
    44041 aatattattt aaatcaatat gctttaaagt ctagtttaca agcttgatat atatgatgta
    44101 taatcaatat gtatgtctat aattaaaaca attttgcaat cctatagatt gattgtttaa
    44161 agttatataa agaatataaa aaagaataag agagaggacg attaatatga aattaggtat
    44221 agttggttta ccaaatgtag gtaaaagcac actatttaac gcaataactc aagcaggtgc
    44281 agaatctgca aattaccctt tttgtacaat agacccaaat gtgggagttg tatctgttcc
    44341 agatgaaaga ttaaacaaac tacaagaatt atataattct gaaaaaatag ttcctactgc
    44401 tatagaattt tgtgatatag caggtttagt tagaggagct tctaaaggag aaggtttagg
    44461 aaataaattc ttatcacata taagagaagt tgatgcaata gttcatgttg ttagatgttt
    44521 tgaggatgaa aatgttgtac atgtagatgg ttctgtagac ccacttcgtg atatagaaac
    44581 tataaactta gaattaattt tctcagatat agagattctt gaaagaagaa ttaataaaac
    44641 tcaaaaagct gctaaggctg ataaaacttt aggttctgaa cttgatttat taaaatcaat
    44701 aatgtctact ttagaagaaa gtaaatgtgt aagaactatg gaatttacag aagatgaaca
    44761 aacattcgta aattcattgg atttacttac atctaagcct gtaatatatg cttcaaatgt
    44821 atcagaagat gatttagctg ataatggaga aaataataaa tatgttcaac aagttaaagc
    44881 atttgcagaa acagaagatg ccgaagttgt tgtagtatgt gcacaaatag aagcagaaat
    44941 ttctgaactt gattctgctg aagaaaagaa agagttttta gaaacattag gtcttgaaca
    45001 atcagggctt gataagctta taaaatcttc ttatgcttta cttggtttaa tttcattctt
    45061 aactgctggt ccaaaagaag ttagagcatg gactataaaa gttggaagta aagctcctca
    45121 ggcaggagga aaaatacatt ctgatataga aagaggattt atcagagcag aaacaatagc
    45181 ctttaatgat ttggttgagc atggtactat ggctgctgct aaagaaaaag ggttggttaa
    45241 attagaaggt aaagaataca tagttaaaga tggagatgta atattattta gatttaatgt
    45301 ttaaaatgat taatcgtata cactttgact attatatata ataactaaaa aactaagatt
    45361 ataataatac aatattatct tataataatt atatagaatt taaaaataaa agaagagtat
    45421 ttcaaatgat ttgtataaat tattatgaaa aac
//
LOCUS       DAYAOO010000028        45084 bp    DNA     linear   BCT 12-OCT-2024
DEFINITION  TPA_asm: Clostridioides difficile isolate ST8-SSI-h139-18
            SAMN40601845-rid21577343.denovo.028, whole genome shotgun sequence.
ACCESSION   DAYAOO010000028 DAYAOO010000000
VERSION     DAYAOO010000028.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN40601845
            Sequence Read Archive: SRR28438827
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 45084)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 45084)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-MAY-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-MAY-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002157583.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002157583.1
            Genome Coverage       :: 163x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/11/2024 16:19:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 4,038
            CDSs (total)                      :: 3,963
            Genes (coding)                    :: 3,930
            CDSs (with protein)               :: 3,930
            Genes (RNA)                       :: 75
            rRNAs                             :: 6, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 60
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 33
            CDSs (without protein)            :: 33
            Pseudo Genes (ambiguous residues) :: 0 of 33
            Pseudo Genes (frameshifted)       :: 7 of 33
            Pseudo Genes (incomplete)         :: 25 of 33
            Pseudo Genes (internal stop)      :: 11 of 33
            Pseudo Genes (multiple problems)  :: 8 of 33
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..45084
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN40601845-rid21577343.denovo.028"
                     /isolate="ST8-SSI-h139-18"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Denmark"
                     /collection_date="2018"
                     /collected_by="Statens Serum Institute"
     gene            102..620
                     /locus_tag="ACGI5H_001686"
                     /pseudo
     CDS             102..620
                     /locus_tag="ACGI5H_001686"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888399.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-guided endonuclease TnpB family protein"
     gene            1052..1306
                     /locus_tag="ACGI5H_001687"
     CDS             1052..1306
                     /locus_tag="ACGI5H_001687"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454592.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9697396.1"
                     /translation="MENKDIKLTICIFAFVIGIIVLFCCIGLGQFNMDCIIKQNGGSI
                     ATEQYNIYLEQSISQYRNFGSILVLLGGIGILFDKSVRKY"
     gene            1342..1665
                     /locus_tag="ACGI5H_001688"
     CDS             1342..1665
                     /locus_tag="ACGI5H_001688"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897482.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF6054 family protein"
                     /protein_id="HFG9697397.1"
                     /translation="MARDVFSVKMTPLEAQKMVEKNLEADLVSVDIYNLENNKSIIVT
                     IFEKYYARSNSDAGLVVICENTTGKTLVKITSTGSAIGLFQIDWGTGNNLIKRVKKIL
                     IDYII"
     gene            1939..2091
                     /locus_tag="ACGI5H_001689"
     CDS             1939..2091
                     /locus_tag="ACGI5H_001689"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454589.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9697398.1"
                     /translation="MDNFLFNVLASVTASYIVYLISKLIKKVKSHSTAKSDLKIDINF
                     KYHRKK"
     gene            2360..3208
                     /locus_tag="ACGI5H_001690"
     CDS             2360..3208
                     /locus_tag="ACGI5H_001690"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861517.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SHOCT domain-containing protein"
                     /protein_id="HFG9697399.1"
                     /translation="MWILVPIITIVLLIIAVSSMQYILVMIAFLLIIYSFIEKKIVMG
                     LVSVLFFTYSIYLCATWEDKSLIADNKVETVRAQRETVEREKEMERRRIQEEVDKERY
                     IEKHGMEISENDLKVKLEALVPQEYKGKKYELKVGKFKRYSMYFDLTVQNEKFSNSEE
                     CKKFVKEIANDLKKIKISKAYFKFHSKDDGGIYNSVYIDYFRNIQNNVDNVENLEFNE
                     FELKTEEEEKREQEKIEQEKNSYNNYIQNRVVDPLDRIKKLKELLDSGAITQEEYNKK
                     KKELLE"
     repeat_region   3475..4290
                     /inference="COORDINATES: alignment:crt:1.2"
                     /inference="COORDINATES: alignment:pilercr:v1.02"
                     /rpt_family="CRISPR"
                     /rpt_type=direct
                     /rpt_unit_range=3475..3503
                     /rpt_unit_seq="gttttagattaactatatggaatgtaaat"
     gene            4445..4633
                     /gene="srl"
                     /locus_tag="ACGI5H_001691"
     CDS             4445..4633
                     /gene="srl"
                     /locus_tag="ACGI5H_001691"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454585.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="virulence factor Srl"
                     /protein_id="HFG9697400.1"
                     /translation="MNKIATKSRAEYMKNCRKDKRGFSVLLDKEKLDKFDEVLEEKNL
                     TKKEWLEEKIDEELEQKE"
     gene            4753..5118
                     /locus_tag="ACGI5H_001692"
     CDS             4753..5118
                     /locus_tag="ACGI5H_001692"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903136.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Bro-N domain-containing protein"
                     /protein_id="HFG9697401.1"
                     /translation="MKNELMMFEGKEIEVFEFEGRILFNSKDVANCLDIKNVNENIIL
                     MNEKQVVKLRNSDISNTDIRKLNNAGENFLTESGVYKLIFKSRKEEAERFQDWISDEV
                     LPSIRQTGAYITNNVIPKS"
     gene            5171..5566
                     /locus_tag="ACGI5H_001693"
     CDS             5171..5566
                     /locus_tag="ACGI5H_001693"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9697402.1"
                     /translation="MLKELLDDAGFDNKSKLLTAKTLYKKAEIDLPIEINEEEHYFDT
                     KQIASKLKIYSKSNKPAQMAVCEIIKKIDLEDGEVKGVWEINGSWTGTVNKYTKSVID
                     KVRTWIEENNRPTKIAGEKKNYYVFYKIE"
     gene            5618..5779
                     /locus_tag="ACGI5H_001694"
     CDS             5618..5779
                     /locus_tag="ACGI5H_001694"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454578.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9697403.1"
                     /translation="MCENLLDNMYIEKRKEEYRIKLLKIRETDIDIYNKLESIVYKLS
                     EKKLEKNNK"
     gene            complement(6107..6571)
                     /locus_tag="ACGI5H_001695"
     CDS             complement(6107..6571)
                     /locus_tag="ACGI5H_001695"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454576.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9697404.1"
                     /translation="MDFGEVKSELSDKDLKDNEEALNKYKKYYLKVYKYYSEMDSIKS
                     IQDIEIEQSRLKGQLQKNSNPIFALYISIMAVVFSTTINLTFDLSDITNYFIRMIMTL
                     LFIVLLIFLVNKGILPIAIPYRNNIQFYTTALDVLEDMKNKILRERKYKKRR"
     gene            complement(6707..7024)
                     /locus_tag="ACGI5H_001696"
     CDS             complement(6707..7024)
                     /locus_tag="ACGI5H_001696"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897465.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9697405.1"
                     /translation="MDFGNINLILIGIIVIIGTTIIYLIKPKTAFCSKKYFNKLESIY
                     GNIDKKKTVKLEVLYRYVTGLEYIAIGLFTRRLDITIIAIILVAIITTALYYLIRKKY
                     ITI"
     gene            complement(7307..7603)
                     /locus_tag="ACGI5H_001697"
     CDS             complement(7307..7603)
                     /locus_tag="ACGI5H_001697"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903134.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9697406.1"
                     /translation="MYFKTYILKREVNNKQLEITRSFDLDNLICTATEILKDNEIDLI
                     ITDEVNNVVWRNEKSTPPARECLVIAIEVYWWYTSIFLLYHINYVIKKNYLNRF"
     gene            complement(7622..8035)
                     /locus_tag="ACGI5H_001698"
     CDS             complement(7622..8035)
                     /locus_tag="ACGI5H_001698"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423175.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9697407.1"
                     /translation="MKVKSKRSFIVGIIVCVLCCASLVIYCILKDKRFLISSFLLIVI
                     AIFNFCNAFSRKGIVEELHDSTDERDLYLTMKTSHILVKIMNYTLFTFTFLFIIAYSA
                     WKNQSLLVIAITLCVIEIFLFVAYLLINIFLEKKE"
     gene            complement(8019..8252)
                     /locus_tag="ACGI5H_001699"
     CDS             complement(8019..8252)
                     /locus_tag="ACGI5H_001699"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423177.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HFG9697408.1"
                     /translation="MKTKVREFRTNMGLTQQQLADLVHVSNRTIISIEKEQYSPSLML
                     AYRMAQVFGTTIEELCCLKENKEMEDKKHESKE"
     gene            8471..8845
                     /locus_tag="ACGI5H_001700"
     CDS             8471..8845
                     /locus_tag="ACGI5H_001700"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430377.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0045892 - negative regulation of
                     DNA-templated transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="BlaI/MecI/CopY family transcriptional regulator"
                     /protein_id="HFG9697409.1"
                     /translation="MKISKLPEAELKVMRYICEANKVLTSRELVAAMEEKYEWNESTT
                     FTVLKRLERREFLSTEKIGKLTHYNILVKEKKYLRFETKEFLKNIHKNSISSLMSALH
                     GEDDEVDEDKLSELEECFKNLK"
     gene            9457..10149
                     /locus_tag="ACGI5H_001701"
     CDS             9457..10149
                     /locus_tag="ACGI5H_001701"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423181.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000156 - phosphorelay response regulator
                     activity [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HFG9697410.1"
                     /translation="MYNILVVDDDKEIVDSIEIYLKSEGFKIYKAYDGMKTLEIITEN
                     DIHLILMDIMMPKLDGIKATVKIREERNIPIILISAKSEDTDKIIGLNIGADDYITKP
                     FNLLELIARVKSNLRRYVTLGNYEDTCKEILKSGALELNTLTKEVKIDGENIKMTPIE
                     YKIIELLLENKGRVFSIDEIYEKVWNEESFNSENTVAVHIRRIREKIEINPKEPRFLK
                     VVWGVGYKIEKF"
     gene            10345..12405
                     /locus_tag="ACGI5H_001702"
     CDS             10345..12405
                     /locus_tag="ACGI5H_001702"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897457.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000155 - phosphorelay sensor kinase
                     activity [Evidence IEA];
                     GO_process: GO:0007165 - signal transduction [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="histidine kinase dimerization/phospho-acceptor
                     domain-containing protein"
                     /protein_id="HFG9697411.1"
                     /translation="MEKYRVLKLVSLIIISISFPLTILLVTIGLAEPKYNIQKTSTKS
                     GIFDISDDFYDSNIFDEGTMASLLPKFKLSVGGKLTSKEKGKFQQEGKSIDLSSSDSE
                     YDKIMINEQASEEYLSYLKNIKVYVINTYTGVFYTNTSYASLYDFKQKTKSYCNVEII
                     NKIGKSSYIKTINGEKFELNNLSLELNEVDEGFEAYVSFPEEPTIEDGIVYTNFQIFK
                     QATEKVRLFFVASLSLAIICLLSIILYIKIKGEVLKRNNVFLLIYSKIPMEFNVILVS
                     ISIAILTIYALAVSYHIDVIALVSLSLLIVSNNIFFINVQLSYLENKMCIFKTSIIVR
                     VILWLIKTVREVSNAIKKVSLARKVIVIVIISLALIMAISTRSIGMGLLFSICIFLGF
                     TIYITKRLSYLSYVIEGTERIKKGELDYKIKITGNDNFTSLAENINNIGEGLDRAIEE
                     QVKSERMKSDLITNVSHDLKTPLTSIINYVDLIKKEESIQPEYINDYINVLESKSKRL
                     KLLIEDLFEASRVSSGNIELQISKIDLVQLLRQSIGELEEKLSKNNLYLKLNVPNDKV
                     YIWADGRRMYRVFENLLSNIAKYSLEETRVYIDVYDYGENVKVTMKNISSYELNFDPS
                     EIMERFKRADESRNTEGSGLGLAIARDLVALQGGKFYIEIDGDLFKANLEFQKYEEEI
                     TNME"
     gene            complement(12610..12933)
                     /locus_tag="ACGI5H_001703"
     CDS             complement(12610..12933)
                     /locus_tag="ACGI5H_001703"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454564.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AzlD domain-containing protein"
                     /protein_id="HFG9697412.1"
                     /translation="MNNNYIFFIIIGMYIVTYLPRVLPMLIFSKKEMPDFLKKIMKFI
                     PVAILTSLTAKDVFFNGDSLYLSIANPKIISFMIVLLVAYKFKSIGISIITGVISIYL
                     FGIIL"
     gene            complement(12926..13627)
                     /locus_tag="ACGI5H_001704"
     CDS             complement(12926..13627)
                     /locus_tag="ACGI5H_001704"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430383.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_component: GO:1902495 - transmembrane transporter
                     complex [Evidence IEA];
                     GO_process: GO:0006865 - amino acid transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="AzlC family ABC transporter permease"
                     /protein_id="HFG9697413.1"
                     /translation="MERTQQLKESFIASIPIFLGYIPIGIVGGILLQKSGLSPFQIAL
                     MVTLVFGGSSQFIAASMISTGASVTSIVLTTFIVNLRHFLMSSNLNMYIKNKSPKFIL
                     PFCHTITDETFAVNYEKFTAGNWSDRNAIYLNFFCLISSVLANFIGAFLGESISIDSS
                     ISGFILTSMFIALIVSQIKNKIYIVVFISSIIISVILYALFKSNLVIIVASILASLIG
                     FFIEESYCKKEESYE"
     gene            complement(13905..15290)
                     /locus_tag="ACGI5H_001705"
     CDS             complement(13905..15290)
                     /locus_tag="ACGI5H_001705"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893561.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PLP-dependent aminotransferase family protein"
                     /protein_id="HFG9697414.1"
                     /translation="MPINSFENYPMNWKPKRPSKGQILYKALAEQLEQDINNGFLLPG
                     TKLPPQRELADFLDVNVSTISRAFKICEKKGLISGVTGSGTFVSYDTRSNLFLMSSNN
                     KITFIEMGTMNPDFTLEEMNTLFKHIIKEIDFKTIFQYGQRDGAKWQKEAIAKLIYKA
                     GLETTSDSLLPASGGQNAIVAILAGLFQHGDRIGVDPLTYPGIKTAAKMLGIQLIPIK
                     QEDNEISEEGLLYACKNENIKGLYIIPDYQNPTTHIMSQNGRKMIANIASKYNLIVIE
                     DAIHSLLNETHLNPVASYLPNQTIYITSLSKIIAPSLRLAYISTPKQYREALSSALYN
                     INLSQSYFLTEIAYRMITSGEADKLINARRKSARRRNKIINQYLSGYNLLGNEECIFR
                     WLILPDGIMAEKFEIQALKEGVQVYASERFAVGKEKPISAIRIAVCATESTEELKAGL
                     SVLKRLLEEKK"
     gene            complement(15398..16636)
                     /locus_tag="ACGI5H_001706"
     CDS             complement(15398..16636)
                     /locus_tag="ACGI5H_001706"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454561.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M56 family metallopeptidase"
                     /protein_id="HFG9697415.1"
                     /translation="MELFIEVIKFNIYISPLILFFILFTKKISKYTFKFNYFICLLIV
                     VRMMFISKINLNILNINNTTINIYKHNIDNYIPYDQGITLDIFMYIWILGIIAISFYY
                     LRTNFKFYNYIENFKKEILEIDITSILDEQAKELSINKKLQIYKVKGIYSPAIIGLTR
                     CKIIIPEKKYNNKELRFIFKHELIHYKRKDNLFKLLISIICIIYWFNPILYLLKKYFH
                     ELCELSCDEIVIDKCTTSEIKEYAYIILDTIKYQKSLKYSSFVSQFLNKKNIILKKRL
                     DSMFNQDKKKINLGLKFLLTFIIIGSIFSINSNFKQNEDVEYTIGKINYNKNGETYGT
                     HIIDSNGNSIEPELIQTIGRGKKVGYVKKRDLYDCDNQPKTPEEAVLYTRKRNFNIFK
                     KTIPLYDKEGIKIIGRFEIN"
     gene            complement(16649..17026)
                     /locus_tag="ACGI5H_001707"
     CDS             complement(16649..17026)
                     /locus_tag="ACGI5H_001707"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423207.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0045892 - negative regulation of
                     DNA-templated transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="BlaI/MecI/CopY family transcriptional regulator"
                     /protein_id="HFG9697416.1"
                     /translation="MIILKKIPKSELLVMNFIWDKDIDKIPAREVANYMEISHGWTKG
                     TTGKVLSRLSDKGFLEFEKDGRNTLYTIKVKHEEYLKFETKDFLELIHKNSIHSFISS
                     LGCGNEISDDDIKELEQWLKKRK"
     gene            complement(17545..17967)
                     /locus_tag="ACGI5H_001708"
     CDS             complement(17545..17967)
                     /locus_tag="ACGI5H_001708"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3284 domain-containing protein"
                     /protein_id="HFG9697417.1"
                     /translation="MNTFKTEVLLKYSAKDIFNIFTKSARLNFPNFNEKKAVGTFVQQ
                     KNNKRFKVEITNFEKNRVYEIKTSNKRESTITRYELVHIDLENTKLIFIESESKRNIF
                     GKINSALVRVLFGKRQPEEFNKFIKKLEMELENNSVNL"
     gene            18445..21348
                     /locus_tag="ACGI5H_001709"
     CDS             18445..21348
                     /locus_tag="ACGI5H_001709"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0008134 - transcription factor binding
                     [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sigma 54-interacting transcriptional regulator"
                     /protein_id="HFG9697418.1"
                     /translation="MELRDKLVNIINTENKKDPLTDVQIAKFLSTTRENITNLRKELN
                     ISNSRQRRYPYLKSAISAILQKNKNISISEITRELMTEGFNISRRVVEELLPKESLEM
                     DVVEEDEEESNDPFETLIGNKGSLRNAVEQAKSAILYPPKGLPTLIIGESGVGKSLFS
                     RHMYEFAKQKKIVKESSNFVVFNCADYSDNPQLLLSLLFGYKKGAFTGAEYDTPGLVE
                     EADEGVLFLDEIHRLPPKGQEILFSILDRGKFRRLGETNAERKVSIMLIGATTENVET
                     NLLLTFRRRIPMLITLPPLHDRLLKEKIDLIYNIFQQECNRINAKIFVDKNVIEILAL
                     KKFSGNIGQLQNMIQVLCARAFMKFINSKDEDSESIVVVDINEVLKLKDSFKDAAFQE
                     IEYTEIRKYLKNAIFIPFNLEESSVKGSLLSDEYILPEDIYKTIEKKYYDLKSLDIED
                     IDIENILWTFILNRFADLKFNLDSNEEIFSMSDLNSFVSDSLVKLVKELMNDIVEKNM
                     NLEVNKNMFKYLAIHLEEAIKRIKLNQKIINVNLEKIKIDFSKEYEISKSFAIKIEES
                     IGIKISDDEIGFITLYIKSALKNEVKKDKVGLIIISHGRIATETVNVVKELLGVKFPV
                     AIDMPLDEKPINIYNKAVELSKIIDQGKGILFLVDIGSLTNIGQIVNKRTNISTKTID
                     RVDLLMALEATRKVSMGEEELDEIFFSLLKDRMGYNYELEKHIDKSNAIITLCLTGEG
                     TAKYISKTLEEKYDNTKCYQMSALDESLFCKIENLKETNNILAIVGTINPKIPGINFI
                     PYNKELFKNLDIYLSKSKQQDDRPIKSYERMLDEDLVIFEPDIYFKKDLLEYVCSILI
                     NKEYVEKDYLDSVLHREEMLPTYSKGAIGVPHGDSSTVNSTRFVFVKLKNPIDWGVGN
                     VNFIFMPVFQANDKEIVKNVLEILKDAEFMNNANKCFDKDAFRRIIFDKFKHL"
     gene            21381..21827
                     /locus_tag="ACGI5H_001710"
     CDS             21381..21827
                     /locus_tag="ACGI5H_001710"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:1902495 - transmembrane transporter
                     complex [Evidence IEA];
                     GO_function: GO:0016301 - kinase activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA];
                     GO_process: GO:0016310 - phosphorylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HFG9697419.1"
                     /translation="MNVDLISLGLESNDYESVIEELGSIMCKKEYVKETYINAVLERE
                     RTLPTGLDIGDMCVAIPHTDSKHVNESNVAVGILKNPVKFNSMIDPKDRLDVELVFLL
                     AVKNPDSQVKLLKDLMSVFQNIKLLKNIKNASTKEEVAKLLDFIEI"
     gene            21950..22252
                     /locus_tag="ACGI5H_001711"
     CDS             21950..22252
                     /locus_tag="ACGI5H_001711"
                     /EC_number="2.7.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430389.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HFG9697420.1"
                     /translation="MKQFNVLSVCGSGTVTSSMVAGKLKEVLGNKGISITTTEARPTE
                     ALNLAQSGRFDFITFTSPLQTGDYGIPTINAFACLTGIGEEAFFEEVLTVIEGIDK"
     gene            22433..23839
                     /locus_tag="ACGI5H_001712"
     CDS             22433..23839
                     /locus_tag="ACGI5H_001712"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454555.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit IIC"
                     /protein_id="HFG9697421.1"
                     /translation="MLEFMKSIIDTFGSAIIVPIIIFIIAKIFKVTTKKSFLSAVYAG
                     VALQGFTLILNSFTPVITPVINRMVESTGVNLPVFDVGWQATSLVAFSTSAGMIYLGL
                     GILLQTILFLIKWTDVFQPSDLWNNYSYMVWGAMVIGVTGNFPLGIACMVLLNLYSLL
                     ISELVAKRWSSYYRYPNCTIIAMHNVEASVFAVFADPIYNKLGLNKIKLNPKELEKKL
                     GFLGEPITLGLFLGMFIGILGNMTRINTMEAWGEIMKVGISTSAVMAIFPKVASMFAQ
                     AFAPITEAARKIMQKAGNREWYIAVNDAVGYGEPATLISGLILIPIMLVIAMVLPGNK
                     VLPVVDLLAIPYMVQGLVAIHNGNIPKVLVSGIIWFGLGLYVCTSTAPLFTDMATNIG
                     VAIPAGAMLITSFNILGKPLMGLVFFAFLSANPIYIGLSVVIYFVLWALFRKNKTSIL
                     DYLEKQALKNVEEEPVAV"
     gene            24183..25241
                     /locus_tag="ACGI5H_001713"
     CDS             24183..25241
                     /locus_tag="ACGI5H_001713"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903127.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactitol-1-phosphate 5-dehydrogenase"
                     /protein_id="HFG9697422.1"
                     /translation="MGNKMRASVLYNVGDVRYEMVNIPEITDTQVLVNVKYVGICGSD
                     LPRSMVSGLSGNTKYPLILGHEFSGEVVKIGEKVKHINVGDRVAVAPLVPCGKCDYCN
                     EGNFGLCDDYNIIGTRVNGAFAEYVRVPEEHILKLPDTLDYETAAGIEPATIAYHGIS
                     KSNIRVGDSVVVLGCGPIGQFVIQWAKVFGASKIIAVDIFDEKLELSKLLGANYILNS
                     KEVNVIKEIKKITNGGADVVIETAGSRFTQEQSLFVAKKRGNIVFVGISHTELPLSAD
                     ATECILRGELTLKGSWNSYTSPYPGRAWTATLDFMEKGDIIFKPMISDKIGLNEVGDF
                     LSKMSKREINFNKILVEI"
     gene            25340..26026
                     /gene="araD"
                     /locus_tag="ACGI5H_001714"
     CDS             25340..26026
                     /gene="araD"
                     /locus_tag="ACGI5H_001714"
                     /EC_number="5.1.3.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729071.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA];
                     GO_function: GO:0008742 - L-ribulose-phosphate 4-epimerase
                     activity [Evidence IEA];
                     GO_process: GO:0019568 - arabinose catabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="L-ribulose-5-phosphate 4-epimerase"
                     /protein_id="HFG9697423.1"
                     /translation="MLENLKEEVLKANLELPKKKLITYTWGNVSGIDREKGLVVIKPS
                     GVEYSNMTVEDMVVVDLEGNIVDGKLRPSSDTPTHLVLYKEFEELGGIVHTHSSWATI
                     WAQIGKSIPSCGTTHADYFYGSIPCTRKMTREEICNEYEKETGNVIIEEFMGRNPIHC
                     PGIIVNDHGPFTWGKDANEAVHNAVVLEEVAKMAYYTELMSPDNIMDKVLMNKHFSRK
                     HGKNAYYGQK"
     gene            26044..26691
                     /locus_tag="ACGI5H_001715"
     CDS             26044..26691
                     /locus_tag="ACGI5H_001715"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861507.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class II aldolase/adducin family protein"
                     /protein_id="HFG9697424.1"
                     /translation="MLDSLKGKVVEIAIKAEHYGLCKEKTGNFSIRDKDTGYILITPS
                     GVGREELKVEHICVLDLDGNVIEVEKGIKPSSEVLMHIEIYKTRENINAISHTHSLYA
                     TAFSVAKKPIIPIVYESVNYGGYVDIASYERPGTLKLAKSVSKLLIDTDACLLERHGL
                     TTVGNDLDEALLKSRYVEEVAEIYYRSLVLNQFKELEVVDVDEFKSWKYPEEIKF"
     gene            complement(26864..28231)
                     /locus_tag="ACGI5H_001716"
     CDS             complement(26864..28231)
                     /locus_tag="ACGI5H_001716"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893558.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0005283 - amino acid:sodium symporter
                     activity [Evidence IEA];
                     GO_function: GO:0015293 - symporter activity [Evidence
                     IEA];
                     GO_process: GO:0006814 - sodium ion transport [Evidence
                     IEA];
                     GO_process: GO:0006865 - amino acid transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="alanine/glycine:cation symporter family protein"
                     /protein_id="HFG9697425.1"
                     /translation="MNLIDILNKVDAFIWGPPLLVLLVGTGILLTVKLGVVQITKLPR
                     ALKLIFSAENKGSGDVSSFAALCTALAATVGTGNIVGVATAIKAGGPGALFWMWIAAF
                     FGMATKYSEGVLAIKYRTKDKNGQVSGGPMYYIVNGMGEKWRPLAIFFAISGILVALL
                     GIGTFTQVNSITDAINNSFGIDPRITGVVLAVFVALVVFGGLKSISNVATKIVPFMAV
                     IYVVICGIILISFWNKIPETFMLIIKSAFTPTAATGGFLGATMSLAIRNGIARGVFSN
                     ESGLGSAPIAAAAAKTEWPAEQGLISMTGTFIDTIIICTLTGFSLVISGVWCSDLNGA
                     VMTQAAFNGAIPTFGPILLTVSLTLFAFTTILGWSYYGERCFEFLFGVKGMNGYRTVF
                     VAMVLLGAFLKLEVVWIIADIVNGLMAIPNLIALLALSPIIVSETKKYFEHINSPENQ
                     IKKNA"
     regulatory      complement(28421..28509)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00504"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="glycine riboswitch; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="glycine"
                     /db_xref="RFAM:RF00504"
     gene            28937..31057
                     /locus_tag="ACGI5H_001717"
     CDS             28937..31057
                     /locus_tag="ACGI5H_001717"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003440272.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase III"
                     /protein_id="HFG9697426.1"
                     /translation="MGKILVLAEKPSVGRDIAKVLGSKNEKNGYIEGPKYVITWALGH
                     LVTLADPESYGERYKSWSLEDLPILPKHLKTVVIKKSGKQFNTVKSQMNRNDIDEIVI
                     ATDAGREGELVARWIIEKSQVKKPIKRLWISSSTDKAIKDGFAKLRSGKEYENLYYSA
                     IARAEADWIIGINATRALTTKYNAQLSCGRVQTPTLAMLLKREEEIRNFKPKEYYGLE
                     LIATKGNSDIKFIWNDKNNNSSTFSKEKIESTLKKVKGVDIKISEVNKSYKKKYSPAL
                     YDLTELQRDANKMFGFSAKETLSIMQKLYEHHKVLTYPRTDSRYLTSDIVGTLKDRIK
                     AVNISDYSKICNRLLKSNIIANKSFVDNSKVTDHHAIIPTEQKVFMSDFSDKERKIYN
                     LVVKRFLAVLSPPFEYEQTTISATVEGEIFKAKGNKVINLGWKESYKDIEDEDEYESI
                     PNVLEKDVLKVKGLKITSGKTNPPPYLNEGTLLTAMEKNGLGTVATRADIIEKLFNSF
                     LMEKKNKDIYITSKGRQLLDLVPVDLKTPELTASWEKKLLDISKGKLSKNTFINDMKD
                     YSKDIVLEVKNSDNKFKHDNLTKNRCPECGKFMLEVNGKKGKMLICEDRECNTRKTIS
                     QVTNSRCPNCHKKLELRGEGEGRLFTCSCGYREKLSSFNKRKQEEKQKASKKDVNQYL
                     KNQNKNQETFNNPFAEALAKLKNK"
     gene            31161..32414
                     /locus_tag="ACGI5H_001718"
     CDS             31161..32414
                     /locus_tag="ACGI5H_001718"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729073.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar protein FliS"
                     /protein_id="HFG9697427.1"
                     /translation="MDLSGIFKYYCKECENTWNNSSVELFENIETYSKDSQKKREKEL
                     DKLLNTISVHLERYPSDAVLRKMWVKKGEVFLQKTLEKENIFKLEKMDVEDRKKFLDI
                     TKQFIRDARKFDDDLPIGDIMQAMRNVWISNALQLLFGKEVYYSKANFAYSMLYPYTD
                     NYLDNTNIDKNDKILFNNWLEKRLLGEHIKSKDYHESKVSQMIDYIESVYPREKFTEV
                     YESLLLIFKSQVNSLKQHGKENHLCKEDLLSISIEKGGSSVLVDGYLISGLMTKEEIE
                     FCIGYGFLLQISDDLQDIKEDLKYNHKTIITEMSKEGTLDKVVNKLINFTIELIDSFK
                     INNKNKSVIAMIKNDCLMLILFSVVYNAEFFSVGYIKEVEKFIPYTIDYSLEIEEKIK
                     EKFKNIDVLNNENEYKEMIDIICAE"
     gene            complement(32568..33629)
                     /gene="ytvI"
                     /locus_tag="ACGI5H_001719"
     CDS             complement(32568..33629)
                     /gene="ytvI"
                     /locus_tag="ACGI5H_001719"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890464.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0003674 - molecular_function [Evidence
                     IEA];
                     GO_process: GO:0030436 - asexual sporulation [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sporulation integral membrane protein YtvI"
                     /protein_id="HFG9697428.1"
                     /translation="MDIQKQKNFIIKFTYVVLITSIVYIVLKFLLPLLMPFVISFIIA
                     SILRPIIRLITNNTNLNRTLISIVILLIFYGLCIFLLVSFGVKIFASVSDVFFRLPEI
                     YKSSIQPTLNTLFSKIDASTPNVNLALILGWDNISQSMMSLVASISTNALNAIASIAS
                     KTPAFMLKLIITLIASFFFTFDYQKIVNFILKQFPEKSQFMIINIKNSSINALLKLLK
                     AYAILLSVTFIELLIGLTILKVENAFTISVIIALVDILPVLGTGSILTPWMIISLING
                     NINLAIGLLILYIIITVVRQILEPKVVGHQIGLYPLITLMCMFVGAQLFGIAGLFGFP
                     IAATIIKNLHDNGIITAFK"
     gene            33903..34643
                     /locus_tag="ACGI5H_001720"
     CDS             33903..34643
                     /locus_tag="ACGI5H_001720"
                     /inference="COORDINATES: protein motif:HMM:NF024744.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-protein phosphatase"
                     /protein_id="HFG9697429.1"
                     /translation="MKNFRDLGGNKTEDGRTVKKGLFYRSAKLSNLSENDIKILKELN
                     IKYIFDYRSDEEARKHPSTIISNIKNIRIPAMRELEESGGSFGSIEDMIDGLFEKDGA
                     FNMLNNSYYNLPINNPSYKKLVELIRDYSNLPILNHCTAGKDRTGVGSAIILMILGVS
                     RENIMKDYLKSNDFADKEIERFIEYKPKFKDIPKENLKYIFGVNEEYMKTAFRRIDEE
                     YISVEAYLYGEFNLNKEEIRKLRNQYLE"
     gene            34655..36433
                     /locus_tag="ACGI5H_001721"
     CDS             34655..36433
                     /locus_tag="ACGI5H_001721"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003440263.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antiterminator"
                     /protein_id="HFG9697430.1"
                     /translation="MSLNITARQINIIKILLNSKDTISGIALSQEIGCSSKTIQNEIK
                     DINKQLRNGKILSIRGVGYKLEGSFDEVNLNSNLYDDVDRVEYIIRKILTLSNEEKNT
                     IKLEDLADSMYVSVSTVKNDLKEVKRMLEKYSISVKSKHKQGICVLESEDKILNCIVD
                     LSNKRDNQLSLNDFLNDDIKERKLLIKKLLLDILNENGLVLTDIEFKSVLNNILVMLS
                     RHKYNEKEFIENYIENYRSKRSSILENEQNKEIIINSIKTFCKNLKLATSIDISNDKV
                     FEEFLYKHISSLCKKIKLGINQSPIMAQDIKIKYPFAFELANIAKKTIEKDLKIEINE
                     DEVANIALHIGGAVERASYNNKDKVFKTIIVCTSGIGTSMLIKAKLENIFKEKLEILK
                     IIPSYLVEYIKVIDVDFVISTVPIEVGDVPVINISPILSEKEIRLIEKYIETGNIYLD
                     LDIKSLFDSELFFTDLVFKRKEEVIDFMASKLVQKGYIDEDMKKSYFEREKIATTEIG
                     NMVTIPHGAIGKIFDNKIAIGILKKPISWEISDVRLIIMLALDKDKILDYEVIFSKIY
                     KRVDSIAKVISICENSSFEKFVNLFN"
     gene            36600..37517
                     /gene="pfkB"
                     /locus_tag="ACGI5H_001722"
     CDS             36600..37517
                     /gene="pfkB"
                     /locus_tag="ACGI5H_001722"
                     /EC_number="2.7.1.56"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890461.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008662 - 1-phosphofructokinase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="1-phosphofructokinase"
                     /protein_id="HFG9697431.1"
                     /translation="MIYTVTLNPSIDYIVKLDELKTGSTNRVKEEYVYPGGKGINVSR
                     IFKELGNDNTSLGFISGFTGEYIIRTLEEKELKTDFIKIKSGFSRINVKIKALKETEI
                     NGQGPNIDDEDIDTLYKKLDKLNQDDILILAGSIPSTLDEKLYENIMARLEKKNIKVV
                     VDATKNLLLNVLKYKPFLIKPNNDELEELFGVKLNSIEDMVKYARRLKEMGAINVLVS
                     MGKDGALLITEEDEVLISDVPKGKVKNSVGAGDSMVAGFISGYLNTGKYDYALKLGAA
                     SGSATAFSYDLAKREYIDKLVNEISVKQF"
     gene            37554..39473
                     /locus_tag="ACGI5H_001723"
     CDS             37554..39473
                     /locus_tag="ACGI5H_001723"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423248.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0022877 -
                     protein-N(PI)-phosphohistidine-fructose phosphotransferase
                     system transporter activity [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="fructose-specific PTS transporter subunit EIIC"
                     /protein_id="HFG9697432.1"
                     /translation="MKIIDLLDEKSIKLNLNSKTKSEAIEELVDLVANSGNLNDKENY
                     KKAILAREEMSTTGIGEGVAIPHAKNSSVTKACIAAAVSKEGIDYESFDGSLSNLFFM
                     IAAPDGANNTHLEVLSRLSTILMDEDFRNKLINSSSEKEFKEIIDKKEREKFSEEYQD
                     EKVTEKNIIDTKENDANKYPKVLAVTACPTGIAHTFMAAESLNKMAENKGVSIKVETN
                     GSAGVKNKLTKDEIENATCIIVAADKNVEMARFNGKKVIKTKVADGIHKAEELIDKAV
                     NGDAPIYHGGDGSHNESNEESESGFRKVYKHLMNGVSNMLPFVIGGGILIAIAFLLDD
                     YTINPSNFGSNTPIAAFFKGIGDKAFGFMLPVLAGYIAYSISDRPAFVVGFVGGALAG
                     DGGSGFLGALLAGFIAGYLVEGLKKIFSVLPASLEGIKPVLLYPLLGTLLMGIIMTFL
                     VIPPVTAINNAMVGFLNGLGGTSKIVLGLVLGGMMAVDMGGPVNKAAYVFGVASLESG
                     QFEIMAAVMAGGMVPPLAIALATTFFKNRFTKEERDSGKVNYVMGLSFVTEGAIPFAA
                     GDPLHVIPACVGGSAVAGALSMLFNAALRAPHGGVFVIPVVTHPFAYILAIAVGALVG
                     MMLLALLKKPLNQEV"
     gene            40069..41595
                     /locus_tag="ACGI5H_001724"
     CDS             40069..41595
                     /locus_tag="ACGI5H_001724"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423262.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-dependent oxidoreductase"
                     /protein_id="HFG9697433.1"
                     /translation="MNESYWFLNSSPKEYNKLGENIKTDCLIVGGGITGLTTAYLLAK
                     EGKKVVLVEADKIGYGTSGRNTGKVTCQHDIFYSKIEKKYGLDKAKSYYNANNEALNL
                     VEQIIEENNIKCDFKRETSFVFTEKEDTIKDIKDEYRTCKKIGINCEYHETIENIPLD
                     IKGAISFTNQGQFNPKKYIDGLAKAAVNLGLKIYENTPVVDLEKGKICRVKTREDNII
                     EAENVIISSHSPWYDGLNFYFAKEYAERAYLMVAVLENKLADGMFISIDDPSITFRQY
                     NDGSENLLIFGGGDHKVGQGGTEKEIFDDLEHYGKEVFKVKDFKGKWSAQDNMSFDNV
                     PYIGYINKREDNIYVATGFSKWGITNGTAAGIIIKDLIINNNSDYKDTFNPSRLGSYF
                     SKDFIKENANVAINYVSGKLKIGSGDMPKNNGEGKIVNIDGKRYGVYKDDNGDFYIVD
                     TTCTHLGCELNFNSEEKTWDCPCHGSRFDYKGNILEGPALKPLKLYGHGDNDVNPKLL
                     "
     gene            41623..42180
                     /locus_tag="ACGI5H_001725"
     CDS             41623..42180
                     /locus_tag="ACGI5H_001725"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003440252.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9697434.1"
                     /translation="MNKLLKPITILLYIVYILSAVFFVANKEYGSLGLVAISLVGTFI
                     LSFINKQTERLLSKELYIMLALFIMFSSLLGTCFNFYDINYYDDFLHLWSGIISCIVA
                     FSIIKYFYTQREISKMSKVFLVIFLFMFSMGVASLWEIGEFLMDTFVGTTTQAGGLED
                     TMIDMVDALIGTIITIPFIVKKSNI"
     gene            42702..43739
                     /locus_tag="ACGI5H_001726"
     CDS             42702..43739
                     /locus_tag="ACGI5H_001726"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430405.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9697435.1"
                     /translation="MLKKWFGIVKKRQKSESVKEEGEVILKNEKILSEEKLIDEEGVV
                     VNIDNQILTKVVNDDNEIEEKIIEEDLLISENTIKLDDKEAIINDKNIELCKKEVQVE
                     SEKIGLNKFEGLDQNENYNLEKNVIEEKKVSECLTEEDLEYIKEIKIKRGKSIKAINL
                     YTKEEWVFDTHIQCSKKLKVPLGYIRENLKYGYMDYFGDAINYLSEVLNIDEYCKSEW
                     SYLDNSKSPSEIFNILNNKIFSIRLSNEKRNEILTNDKIEALKMNYRFECIDEEYDEY
                     FKKYKSIIKRGGKKKVELVNKKGDILEIFKSLEECAIYLQKEKNEVIQMLKYGDTKVG
                     RNFIRYSLRSI"
     gene            43850..44992
                     /locus_tag="ACGI5H_001727"
     CDS             43850..44992
                     /locus_tag="ACGI5H_001727"
                     /EC_number="5.2.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003440250.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase"
                     /protein_id="HFG9697436.1"
                     /translation="MSEEKNPKENTLDESKNSDNVNSKKDDVSDEKNTDNKVKKREIK
                     LNNKTLKAIVAIVAVGAICLGGGYVFGKEAGRKLPATSKHYNSSEVVATIGDKKITGE
                     MLRKRMEPLFYLNAKTTMTDDEIRSYESNMIETMITSDILSSEAAKEKISITNDQLDA
                     QYNNLMSSIESAMGMTKEEFLKQFDLTEKYIKDDMKKELVASKYLNEKSKVTDKEAEN
                     YYNKNKSNYLQVRASHILIKTVDDKGKQVSSSKKAELKKEAEEILKKAQAGEDFATLA
                     KKYSEDSSAESGGDLGFFGKGQMVESFEKAAFALKKGEVSNKLVESDYGYHIIKKTDE
                     KYQPFEEVKSDLVSSLTSEKQNLLIQNLKEKYNVKITDKYQMKAKE"
BASE COUNT        18034 a         4753 c         7358 g        14939 t
ORIGIN      
        1 taagaattaa tatacattaa ttcagctgaa tccaatcaaa atacttaaat aaaagtaatc
       61 tgaaaataac ataattcaaa tcaatttatt caaataaacc tcaatttatc tcaaatctta
      121 agaagtcatt aaacaaactt gctaaattac aaagagaatt atcaagaaaa acaatcggta
      181 gtttaaatag aaataaagca agattaaaag ttgcaagact tcaagaacat atagctaatc
      241 aaagaaatga ttttctacaa aaactatcta ctaaattaat aaaagagaac gatattattt
      301 gcatagaaga tttacaagta aagaatatga ttaggaatcg taaactatct cgctcaattt
      361 ctgatgtgtc atggtcagag tttattcgtc aattagaata caaggctaat tggcatggta
      421 gacaaattgt aaaggtgggt aaattctttg caagttcaca aatatgcaat aaatgtgggt
      481 ataaaaacga ggaagtgaag gacttaaata taagagaatg gatttatcct agttgtaatg
      541 aaactcacga tagagatata aatgcaagta taaatatatt aaaagaagga ttaagactaa
      601 taacaattca aaataaataa cgtatgtaag aaccgtagga actacgggga tagcctgtgg
      661 agaattagta agacatatgt tagtatgcaa aattctgtga agcaggaaac ctgtgacttt
      721 agtcatggga ggttcaggct agtattactc attattgtat tcaaaagcta aagtggaaac
      781 ctagtgaata tatgaattta gaagttaatg agagagcatt agcagccgac tcaatactta
      841 ttaaaattga agatgaagaa gaaacaatga aagaagctga aagagagaaa aagagaggta
      901 gaagaaggta gaatttaaag ttaaaatagt tacattgcta atatatgaaa atgttacaaa
      961 tttggaaata gatggatata tatgttgtat agtataatgt agataatata tcaccaagta
     1021 aaaaacaaca aataaatcta aattatgagg ggtggaaaat aaagatatta aacttacaat
     1081 atgtatattt gcttttgtaa ttggaataat agtgttattt tgctgtatag gtctaggtca
     1141 atttaatatg gattgtatta taaaacaaaa tggtgggtca atagctaccg aacaatacaa
     1201 catatattta gaacaatcta tttcacaata tagaaatttt ggttctatac tggttttact
     1261 aggaggaata ggaatactgt ttgataaaag tgtcagaaaa tactaaaaaa gtatattttt
     1321 atttaggatg tgatgaatga tatggcaaga gatgtattta gtgtaaagat gacaccacta
     1381 gaagcacaga aaatggtaga aaaaaatttg gaagcagatt tagtttctgt tgatatttat
     1441 aacctagaaa ataataagtc tataatagtt acaatctttg aaaaatatta tgcaagaagc
     1501 aatagtgatg caggtttggt agtgatttgt gaaaatacta caggaaaaac acttgttaaa
     1561 attacctcaa ctggtagtgc aattggacta tttcagattg attggggaac aggtaataat
     1621 ttgattaaaa gagtaaaaaa aatacttatt gattatatta tttaattatt ttatgtagat
     1681 attcttaggt tggtatggaa tttgtactaa cctattaagt aatcaataaa actaaataaa
     1741 catagaaagc acttacaaat atgtaggtgc tttttattga aaaaatagaa aataaaataa
     1801 aaagtaagat ataggaaaaa tatgtaagaa ttatatgtta taataattgt agcaagaaga
     1861 tgtaatctac aatttataga gtggagttca tgtattaaaa aattatcctc ccaacgataa
     1921 gaagggaggt gaatatacat ggataatttt ttatttaatg tgttagctag tgtaacagct
     1981 agttacatag tttatttgat tagcaagtta atcaaaaaag taaaaagcca ctctaccgca
     2041 aagagtgact taaagattga tataaatttt aaatatcatc gtaaaaaata actttcagtt
     2101 atagaacttc actctaccgc aaatagattg tagttcttct tgtttttatt ataccacaaa
     2161 ttagaaaaaa tattgcatat aatatttttt atagtcaata aaaatatgaa attttttata
     2221 cacaatgatg atgaatctaa ctagatgaat aaatttaatt gtaaataaga aagtacttac
     2281 ttaaatggta ggtgcttttg ttttgccaaa ttatgctata atattgagtg agatgagtaa
     2341 tttgtggggg aattttataa tgtggatatt agtaccaata ataacaatag tattacttat
     2401 aatagctgtt tcttctatgc aatatatttt agttatgata gcttttttgt tgattatata
     2461 ttcttttata gaaaagaaaa tagttatggg tcttgtgtca gttctttttt tcacttattc
     2521 aatttatctt tgtgcaactt gggaagataa atccttgata gcagataata aagttgagac
     2581 tgttagggca caaagagaaa ctgtagaaag agaaaaagaa atggaaagaa gaagaataca
     2641 agaagaagta gacaaagaaa gatatattga aaaacatgga atggaaatat cagaaaatga
     2701 tttaaaagtt aagctagagg ctttagtacc tcaagaatat aaggggaaga aatatgaatt
     2761 aaaagtagga aaatttaaaa gatatagtat gtattttgat ttaactgtac aaaatgaaaa
     2821 atttagtaat tctgaagaat gtaaaaaatt tgtaaaagaa attgctaatg atcttaaaaa
     2881 aattaaaata agcaaggcgt actttaagtt tcattcaaaa gatgacggcg gtatatataa
     2941 ttctgtttat attgattatt ttagaaacat acaaaataat gtagataatg ttgaaaattt
     3001 agaattcaat gagtttgaac ttaaaaccga agaagaagag aagcgagaac aagagaaaat
     3061 agaacaagaa aaaaacagtt ataataacta cattcaaaac agagtggttg acccactaga
     3121 tagaataaag aaactaaaag agttgctaga ttcaggagca attacacagg aagaatataa
     3181 taaaaagaaa aaagaattat tagaatagat aatatagtaa gcacttacaa gtatgtaggt
     3241 gcttttaaat ttacaaagta ttccatttta attttatagt ttagatttta tgatataata
     3301 aaaatataga agttttgcag tgtgcgatat ttgttacaaa gtagggctta atacttgaaa
     3361 tctaagatgt tgagggtgcg tgataagtgt tatcaattgc actattgccc gctcactgca
     3421 attttaagag tattgtatat atgtaggtat tggaaatgct aagtttattt tggggtttta
     3481 gattaactat atggaatgta aatattacat gggtaaaaat tttgatgatt tttatgacag
     3541 ttttagatta actatatgga atgtaaattg tatagaatta agaatttttt taatactaat
     3601 tatagtttta gattaactat atggaatgta aatattacat ttaatttgca ttgctttgat
     3661 gacttctttg ttttagatta actatatgga atgtaaatgc gtacaaggtt gagaagctcc
     3721 gcaatctcaa cgtcgtgttt tagattaact atatggaatg taaatatttg aaaggaataa
     3781 attttaaatg aatgaaagga taggttttag attaactata tggaatgtaa atcagccaaa
     3841 aacttcgaat ttgaactaaa atgcgtgggt tttagattaa ctatatggaa tgtaaattct
     3901 catgactatt gaataaatat aataaacaag catacgtttt agattaacta tatggaatgt
     3961 aaatttagaa tcaaaagcac ttaatcctag ttctttcata gttttagatt aactatatgg
     4021 aatgtaaata gctttttagc ttcgtctact actttataag caaagcgttt tagattaact
     4081 atatggaatg taaatgatga acaataaaac aatcatctaa agacgaagaa agttttagat
     4141 taactatatg gaatgtaaat gttcctgttg tgttttttac taatcccatt ttatatgttt
     4201 tagattaact atatggaatg taaattgctg tgatttcact aataaaacaa ttaataattg
     4261 tgttttagat taactatgtg gattcaaaat taaataaaca aagaaagcac ttacaaatat
     4321 gtaggtgctt ttattctgct caaaattggt cggttgggta aaatcattag aaaaaattag
     4381 taaaaacctc ttttctgtaa ctcgttacaa tattattatt aatgtaacga gttacagaaa
     4441 agaggtgaat aaaatagcaa ctaaaagtag ggcagagtat atgaaaaatt gtcgaaaaga
     4501 taaaagaggt tttagtgtac ttttagacaa agaaaagtta gataaatttg atgaagtatt
     4561 agaggaaaag aatctaacca agaaagaatg gctagaagaa aaaatcgacg aggaactgga
     4621 acaaaaggaa taaaaaataa gggtcactcc caccgaccaa agtttgagta acccctatga
     4681 tgtatactat cgtatatcaa ttataatata tgtcattcct taaaaaaatc aattattaag
     4741 gagtgtaata ttatgaaaaa tgaattaatg atgtttgaag gaaaagagat tgaagtattt
     4801 gaatttgaag gaagaatttt attcaactca aaagatgtag caaattgttt agacataaaa
     4861 aatgttaatg agaatataat acttatgaat gaaaagcaag ttgtaaagtt aagaaattcg
     4921 gatatcagta atactgacat ccgaaaactt aataatgctg gagaaaattt tcttactgaa
     4981 agtggagtgt ataaattaat ctttaaatca agaaaagaag aagctgagag attccaagac
     5041 tggataagcg atgaagtttt accaagcata agacaaactg gtgcatacat aactaataat
     5101 gtaatcccga aaagttgaga gaaaaagcaa gtgagattga aaaattacag ttgcttataa
     5161 cagtacatct atgttaaaag aattgctaga tgatgcaggc tttgacaata aatcaaaact
     5221 attaacagct aaaacattat ataagaaagc agaaattgat ttaccaatag agataaacga
     5281 agaagaacat tattttgata caaaacaaat agcatctaaa ctgaaaatat attctaagag
     5341 taataaacca gctcagatgg ctgtttgtga gattattaaa aagattgatt tagaagatgg
     5401 tgaagttaaa ggtgtttggg aaattaatgg ttcttggact ggtactgtaa ataaatatac
     5461 aaagagtgta atagataagg tgagaacttg gatagaggaa aataatagac ctaccaagat
     5521 tgcaggtgag aagaagaatt attatgtatt ttacaaaatt gagtaaattt atcagttgta
     5581 ttaaataatt tagtttagtt ttggggggat taatacaatg tgtgagaatt tacttgataa
     5641 tatgtatatt gaaaagagaa aagaagaata tagaattaaa cttttgaaaa taagagaaac
     5701 agatatagat atatataata agttagaaag tatagtatat aaactttctg agaaaaaatt
     5761 agagaaaaat aataaataga catataaagc acttggatat tctactgttt caagtgcttg
     5821 tttggtataa aatggtataa tggagataga gaattatatt aaccaaaaaa tggagaaaat
     5881 agagaagatg atttagttga cgctttatca gtaggagtac ctgcaggtaa gacagaatct
     5941 ctagtacgat tagttggaga tggaataagt gatactcaaa aaagtttaat aaataaaaga
     6001 gaatttagaa atataactca aattggtgga aatggaaatg agaaagcatt tagtgaagta
     6061 gaaaacttag ttaaatagat tagaaggtag caactagagt tggttgttac cttctttttt
     6121 tatactttct ctctctaagt attttatttt tcatatcttc taatacatct aatgcagtag
     6181 tataaaattg tatattattt ctataaggta tagctattgg aagaatgccc ttgttaacta
     6241 aaaaaataag aagtacaata aataaaagtg tcataatcat tctaataaaa taattagtga
     6301 tatctgataa atcaaatgtt aagttaattg ttgtagaaaa tacaacagcc ataatagata
     6361 tatacaaagc aaaaatgggg ttactatttt tttgtaactg tcctttaagc ctagattgct
     6421 ctatttctat atcttgaata ctttttatgg aatccatttc actataatac ttataaactt
     6481 ttaaataata ttttttatac ttgtttaaag cttcttcatt atctttaagg tctttgtcac
     6541 ttaactctga tttaacttcc ccaaaatcca taaaatccct cctacaatgt tatataatat
     6601 actttaattt atagcatatt taagaactta tatcagcaat ttgtcgaacg attttagcta
     6661 aaaatagagt ataatgatag gcttattatt tataagatat tattttttat atagttatat
     6721 atttctttct aattagataa tataatgctg ttgttataat ggctactaat attattgcta
     6781 ttattgtaat atctaatctt cttgtaaata agcctattgc tatatactca agacctgtta
     6841 catagcgata aagtacttct agtttaacag tttttttctt atctatattt ccatatattg
     6901 attctaattt attaaaatat tttttactac aaaaagcagt tttaggttta attaaatata
     6961 ttattgtagt tcctattata actattattc caataagtat aagattgata tttccaaaat
     7021 ccatagcaga tacctcctat taaatttgct tttcttaatc aaagtatatc agtaacacaa
     7081 gtacaaagag tatctaaaat attacaaata ttaacaggat agataaaact atagtaaaaa
     7141 ttgtaataat aaagcgaacg aaaattatca tactaaaaca taagacatgt tataattgta
     7201 ttagatagaa gattaacata caccaaagca ctccttataa taaagagtgc ttattttttt
     7261 gaaattcatc aatatataaa ctatcaagaa ccttattcaa cacaccttaa aatcgattta
     7321 aatagttctt tttgataaca taatttatat gatataataa aaaaatagaa gtgtaccacc
     7381 aatacacttc tatagctata actaagcatt ctcttgctgg gggagtgctt ttttcatttc
     7441 tccaaacaac attatttact tcatcagtaa ttatcaaatc aatctcatta tctttcaaaa
     7501 tctctgttgc agtacaaatt agattatcta agtcaaaact tcgagttatc tctagttgtt
     7561 tgttatttac ttctcttttt agtatataag ttttaaaata catttatatc accccttgta
     7621 tttactcttt tttctctaaa aatatattga taagtaaata tgcaacaaat aaaaaaatct
     7681 caatgacaca tagtgttata gctataacta gaagtgattg atttttccat gcactataag
     7741 ctatgatgaa aagaaatgta aaagtaaata atgtataatt cataatttta actaagatat
     7801 gacttgtttt cattgttaag tacaagtctc tttcatctgt actatcgtgt aattcttcaa
     7861 caatgccttt tcttgaaaaa gcattacaaa aattaaagat tgctattaca attaaaagaa
     7921 atgatgaaat taggaatctt ttatctttta aaatgcaata aataactaaa ctagcacaac
     7981 ataacacaca aactataata cccactataa aacttcgttt actctttact ttcatgtttt
     8041 ttatcctcca tttctttatt ttcttttaaa caacatagtt cttcaatcgt tgtaccaaac
     8101 acttgtgcca tacgataggc aagcataaga gaagggctat attgctcttt ttcaatagaa
     8161 ataattgttc tgtttgatac atggactaaa tcagcgagtt gttgctgtgt tagacccata
     8221 tttgttcgaa attctcgtac ttttgttttc attccataac ctctttctat atgaagctaa
     8281 cttcatgtga agttaacttc ataatatcct aaaatgagta aaatgtcaat ctcattagat
     8341 aagtattata aaacctaaaa gaataatatg gtaaaaattg gatggaatta tttaccttaa
     8401 ttctcttgtt tgtaaaactt tattgatata gaatttaaca tatacataaa tcggcaaagg
     8461 ggcgcgaatt atgaaaatta gtaaattacc agaagcggaa ttaaaagtta tgagatatat
     8521 ttgtgaagct aacaaggtat taacttctag ggaattagtt gctgcaatgg aagaaaaata
     8581 tgagtggaat gaatcaacta catttacagt tttgaaaaga ttagagcgaa gagagttttt
     8641 aagtacagag aaaataggca aacttacaca ttataatata ctagtaaaag agaaaaaata
     8701 tctaaggttt gaaacaaagg aatttttgaa gaacatacat aaaaattcaa tttcaagttt
     8761 aatgtcagcg ttacatggtg aagacgacga agtggatgaa gataaattaa gtgaactcga
     8821 agaatgtttt aagaatttga aataagaaaa tgacaaattg atacataata aataaaatga
     8881 aggtatgaaa ttataacttt ttctaccttc attttgttta ttattctgaa catgttaaga
     8941 aaatgaaata agtttgtatt ttagttatat aaattttaat agaatatgta cagtatatag
     9001 tagatagaat gtataaaaat agaatttaaa taagtagcta ttattgcagt gaaatgaatg
     9061 tttctaagta tatttgggtg gaagaatggt ggaagaaaat tagtgaaatg taattcttcc
     9121 accattcttc cacctagaaa atagaaactg tttaataaga attaatatac attaattcag
     9181 ctgaatgcaa tcaaaatact taaatgaaag taatctgaaa acaacataat tcaaatcaat
     9241 ttattcaaat aaacctcaat ttatcttaaa tcttaagaaa tatttaagaa ttaggataat
     9301 attttcttaa gatttatatt ttattatata gttataaggg aaagttacaa aaatgtaagc
     9361 caaagtaata taacaattta gtcattgttg agaaagggag tgaaagatat tgtataatat
     9421 agataagtat tattatacaa tagaggaagt gaaaatatgt acaatatatt agtagtagac
     9481 gatgataaag aaattgttga ttcgatagaa atatatctta aatcagaagg atttaaaata
     9541 tataaagcat atgatggaat gaaaactttg gaaataataa cagagaatga cattcatcta
     9601 atactaatgg atataatgat gcctaaatta gatggaatca aagcaactgt aaaaatacga
     9661 gaagaaagaa atattccaat aattttaatt tcagcaaaaa gtgaagatac agataaaata
     9721 ataggattaa atattggagc tgatgattat ataacaaagc catttaatct attagagctt
     9781 atagctaggg ttaaatcaaa cttaagacga tatgtaactt taggtaatta tgaagataca
     9841 tgtaaagaaa ttctaaaaag tggagctttg gagttaaata cactaacaaa agaagttaaa
     9901 attgatggtg aaaacataaa aatgactcca attgagtata aaataattga acttctttta
     9961 gaaaataaag gacgagtttt ctcaatagat gagatatacg aaaaagtatg gaatgaggaa
    10021 agttttaatt cagaaaatac agtagcagta catatcagac gaataagaga aaagattgaa
    10081 ataaatccaa aagaaccaag atttttaaag gtggtgtggg gagttggtta taagattgaa
    10141 aaattttagt ggaaaaatta taaaagaaaa gagtttaata tttaattgca ttttgatttt
    10201 agtcattttt acatttacac aaatgttagg aattttaata tgttttaatt ttttctctga
    10261 gagtttaatt tactctatgg ggattatgct tttcttaaac tttattttat ataaaatact
    10321 gacaatgtag atgaggtggg caacttggag aaatatagag tattaaagtt agtttcatta
    10381 atcataatat ctatctcatt tccattaact atattgttgg tgacaatagg acttgctgag
    10441 cctaaataca atatacaaaa aacttctaca aagagtggga tttttgatat atctgatgat
    10501 ttttatgata gtaatatatt tgacgaagga acaatggcaa gtctattacc caagtttaag
    10561 ctatctgtag gtggtaaatt aactagtaaa gaaaaaggta aattccaaca agaaggtaaa
    10621 agtatagatt taagtagtag tgattctgag tatgataaaa tcatgattaa tgaacaagct
    10681 tctgaagaat atttaagtta tctaaaaaat ataaaagtgt atgttattaa tacatacaca
    10741 ggagtatttt atacaaatac gtcatatgct agtttatatg attttaaaca aaaaactaag
    10801 agctattgta atgtagagat aataaataag ataggaaaga gctcatatat taaaacaata
    10861 aatggagaaa aatttgaact gaataatctg agtctggaac taaatgaagt agatgaaggt
    10921 tttgaggcat atgtatcttt tccagaagag ccaactatag aagatggaat agtatacact
    10981 aattttcaaa tatttaaaca agctacagaa aaagtaagat tattttttgt agctagttta
    11041 agtttagcaa ttatatgttt attatctata attttatata tcaaaataaa aggtgaagtt
    11101 ttaaaaagaa ataatgtatt tttactaata tacagtaaga tacctatgga atttaatgta
    11161 atattagtat ctatttcaat tgcaatttta actatatatg ctcttgctgt atcttatcat
    11221 attgatgtaa ttgcattagt ttctttatct ttactgatag tatcaaataa tatatttttt
    11281 ataaatgtgc aattgagcta tttagaaaat aaaatgtgta tatttaagac aagtattata
    11341 gtaagagtga ttttatggtt aataaaaact gtaagggagg tcagtaacgc tataaagaaa
    11401 gtatctttag caaggaaagt tattgttata gtgataatat ctttagcttt aatcatggca
    11461 attagcactc gaagtatagg tatgggatta ctgttttcta tatgtatttt tttaggattt
    11521 acaatatata taactaaaag actttcatat cttagttacg taatagaagg tacagaaaga
    11581 ataaaaaagg gagaattaga ttataagata aaaattactg ggaatgataa ttttacgtct
    11641 ttagctgaaa atataaataa tattggagaa ggtcttgata gagctataga agagcaagta
    11701 aaaagtgaaa gaatgaagtc tgaccttata acaaatgtat ctcatgattt gaaaactcca
    11761 cttacttcta taataaatta tgtagattta attaaaaaag aagaatcaat acaaccagag
    11821 tatataaatg attatataaa tgtacttgag tcaaagtcaa aaagactaaa attattgata
    11881 gaagatttat ttgaagcgag tagagtaagt agtggcaata tagaattaca aattagcaag
    11941 attgatttag tgcaactatt aagacaaagt ataggtgaac ttgaagaaaa attatctaaa
    12001 aataatttat atttaaaatt aaatgttcca aatgataagg tgtatatatg ggcagatgga
    12061 agaagaatgt atagagtatt tgaaaatctt ttatctaata tagcaaaata ttccttagaa
    12121 gaaactagag tctatattga tgtatatgac tatggtgaaa atgtaaaggt aactatgaaa
    12181 aatatatctt cttatgaatt aaattttgac ccaagtgaga ttatggaaag atttaaaaga
    12241 gctgatgaat caaggaatac tgaaggaagt ggattagggc ttgctattgc aagagattta
    12301 gtagctttac aaggtggaaa attttatata gaaatagatg gagatttatt taaagcaaat
    12361 ttagagtttc aaaaatatga agaagaaata acaaatatgg aatgagatag tatttaagta
    12421 tatatatttt tttactgtcg aaagctttta ttataatata ttagaatatt tacagtagag
    12481 aatgaagagt aaaaacagag taactttaag tcactctgtt ttttatttaa aatcaataat
    12541 ataacaactt aaattaaaat tgtacacata gttttaaaat aacttataca ataaaacatt
    12601 atccaaatat cacaagataa ttccaaataa atatatagat atcactcctg taataataga
    12661 aataccaata gatttaaact tatatgcaac aagaagtaca atcataaaag atataatttt
    12721 agggttagct atagataaat atagactatc tccattaaaa aatacatctt tagcagttaa
    12781 ggaagtaagt attgctacag gtataaattt catgattttt ttcaaaaaat caggcatctc
    12841 tttttttgaa aaaattaaca taggaagcac tcttggtaga tatgtaacaa tgtacattcc
    12901 aattataata aaaaatatat aattattatt cataagattc ctccttttta cagtaagatt
    12961 cttctataaa gaaaccaatt aaagatgcta aaattgatgc aactattatt actaaattgc
    13021 ttttgaataa tgcatataaa ataacagaaa taatgattga tgatataaat actacaatat
    13081 aaatcttatt ttttatttga gaaactatta aagctataaa catagaagtc aatatgaagc
    13141 cagaaataga actgtctata gatatacttt ctcctaaaaa tgctccaata aaattagcta
    13201 aaactgatga aattaagcag aagaaattaa gataaatagc atttctatca gaccaatttc
    13261 cagcagtaaa tttttcataa ttaactgcaa aagtttcatc tgttatagta tgacaaaatg
    13321 gcaatataaa ttttggactt ttatttttta tgtacatgtt caaattagaa ctcattagaa
    13381 aatgtcttaa gttaactata aatgtagtca aaacaataga tgttacactt gcaccagtag
    13441 aaatcattga agctgcaatg aattgagaac ttcctccaaa tactaaagtt accattagtg
    13501 ctatttgaaa aggtgaaaga ccagattttt gtaatagtat tcctcctact atacctatag
    13561 gtatataacc taagaatata ggaattgaag caataaagct ttcttttaat tgttgagttc
    13621 tttccacaat aaatcactcc ttttgtatta aatgtattaa agtattcgta aaacagaaaa
    13681 atagattaat tgtataattg caattataat taaaaataaa tttggattaa tatataaaat
    13741 actatacaac aaatagataa tcttaaacgg ttattaaatt ttatctattt gttattatga
    13801 tgtaataata catattaatc tctataagtt aattactatc tggtgtaatt ttattttaac
    13861 aacaaaaaaa aatacacaca attaaaatat tgtgtgcaat acaattattt tttctcttct
    13921 aatagtcttt ttaatacgct caaaccagct ttaagttctt ctgtactttc tgtagcacat
    13981 acagctattc ttattgcaga aattggtttt tcttttccaa cagcaaaacg ttcagaagca
    14041 tagacctgta caccttcttt aagtgcttgt atctcaaatt tttctgccat tattccatca
    14101 ggtagaatca accatctaaa tatacattct tcatttccca aaagattata tccagataaa
    14161 tattgattaa taatcttgtt tcttcttctt gcagatttac ggcgtgcatt aattaattta
    14221 tcggcttcac ctgatgtaat catgcgataa gcaatttctg ttaaaaaata agattgagat
    14281 agattaatgt tgtataatgc gcttgataat gcctctcgat actgtttagg tgtagagata
    14341 tatgctagcc gtaaactagg tgcaataatt tttgataaac tcgtaatata aattgtttga
    14401 ttgggcagat aggaagccac tggatttaaa tgtgtttcat taagtaaact atgaatagca
    14461 tcctcaataa caattaaatt gtatttagat gcaatatttg caatcatttt tcgtccattt
    14521 tgtgacatta tatgtgtagt tggattttga taatctggta ttatgtatag acctttaata
    14581 ttttcatttt tacaagcata taatagtcct tcttcactaa tctcattatc ttcttgttta
    14641 attggaatta gttgaatccc aagcatttta gctgctgtct ttattccagg ataagttaat
    14701 gggtctacac ctattctatc tccatgttga aacaaaccag ctaaaatagc aacaattgca
    14761 ttttgtccac cacttgcagg aagtaagcta tctgatgtag tttcaagccc agctttataa
    14821 attaatttgg caatagcttc tttttgccat ttagcaccat ctctttgtcc atattggaat
    14881 atggttttaa aatctatttc cttaattatg tgtttaaaca aagtattcat ttcttctagt
    14941 gtgaaatctg gattcattgt gcccatttca ataaatgtaa ttttattatt actggacatc
    15001 aagaatagat ttgaacgtgt atcataagat acaaaagttc cacttcctgt aactccactt
    15061 attagacctt ttttttcaca aattttaaaa gctctagaga tagtactcac attaacatct
    15121 aagaaatctg ccaattcacg ttggggtggt aatttagtac ctggtaataa aaatccattg
    15181 ttgatatctt gttctagttg ttctgcaagc gccttatata atatttgccc ttttgaaggt
    15241 ctctttggtt tccagttcat aggataattt tcaaaagaat taattggcat aagttttcac
    15301 ctcacattat taatttgatt ttttctttat ctaaaacaat aaattctaaa gatacaaata
    15361 aaaactgata ggaaataatt ctatcagttt ttgtctttta attgatttca aatcttccta
    15421 taatttttat accttcttta tcataaagag ggattgtttt tttaaatata ttaaaatttc
    15481 tttttcttgt atataaaaca gcttcttctg gtgtctttgg ttgattatca caatcgtaca
    15541 aatctctttt ttttacgtag ccgacttttt tacctctacc tattgtttgt ataagttctg
    15601 gttcaatgga atttccattt gagtctatta tatgtgtacc ataggtttct ccatttttat
    15661 tataattaat cttaccaata gtatattcta catcttcatt ttgtttaaaa ttggagttga
    15721 tagaaaatat tgaccctatt attataaagg ttaataaaaa cttaagacct aaattaattt
    15781 tctttttatc ttgattaaac atagaatcta acctcttttt taaaataata ttttttttat
    15841 ttagaaactg agatacgaat gatgaatact tcaaagattt ttgatacttt attgtatcta
    15901 atattatata tgcatactct ttaatttcac tcgtggtaca cttgtcaatc acaatttcat
    15961 cacaagataa ttcacataat tcatgaaaat atttttttaa taagtataaa attggattga
    16021 accaatatat gatacaaatt atactaatta gaagcttaaa taagttatct tttcttttat
    16081 aatgaattaa ttcatgttta aagatgaatc ttaactcttt attattgtac tttttttctg
    16141 gaattattat tttacagcgt gttaaaccta taatggcagg agaataaata cctttaacct
    16201 tatatatctg aagtttttta tttatactta gttcttttgc ttgttcatct aagatactag
    16261 taatatctat ttctaaaatt tcttttttaa aattttctat gtaattataa aatttaaaat
    16321 ttgttcttaa atagtaaaaa gagattgcta taattcctaa tatccagatg tacataaata
    16381 tatctaaagt aatgccctgg tcatatggta tataattatc gatattatgc ttatagatat
    16441 taatagtagt attattgata tttaatatat ttaaatttat tttagatata aacatcattc
    16501 tgactactat taaaagacat ataaaataat taaacttaaa agtatatttg cttatctttt
    16561 tagtaaataa aatgaaaaaa agaattagtg gacttatgta aatattaaat ttaataactt
    16621 ctataaataa ttccataaaa tacgtctcct attttctttt ttttagccat tgttcaagtt
    16681 cttttatgtc atcatctgat atttcatttc cacaacctaa tgatgatata aagctatgaa
    16741 tagaattttt atgtataagc tctaaaaaat cctttgtttc aaattttaga tattcctcat
    16801 gtttaacttt aatagtgtat aaagtatttc taccatcttt ttcaaattct aaaaaacctt
    16861 tatcacttaa tctagaaagt actttaccag tagtaccttt tgtccatcca tgagaaattt
    16921 ccatataatt agctacttct ctggctggta ttttatctat gtctttatcc catatgaaat
    16981 tcataactaa caactcggat tttggtattt ttttcaatat aatcactcac ctttaacttg
    17041 attatattag acaaatgtct aatagtcaat ataatatatc atcatgtata aataatcttt
    17101 atattatttt atgcttgaga actaagtagt atagatttat agataaaaaa gatattgaga
    17161 gttttatgga agaggggaat atattttcta ttagagataa gaatatgaca tatatttttt
    17221 attgattttt acaaaaatac tatatagtga ataaattaat atcttttcta aattagaaga
    17281 ggagaatctt attagataaa gattatcctc tttattgaaa gtttaaggga tattagagat
    17341 tattaatttt tctctctttt tttaactaaa agcaataata cataaaatta ttattgctaa
    17401 tgatactctt aatgtggtat atagtcatag tgtcacatgt ttatcaatag ttttttcatt
    17461 aattattgta acgaatagta ggactcataa aatacttaga aatatgtttt tagatagatt
    17521 ttaaatatat aatctaactt atatctataa attaacacta ttattctcca attccatttc
    17581 tagttttttt ataaatttat taaattcttc tggttgcctt tttccaaaca atactcttac
    17641 aagagctgaa ttgatttttc caaatatatt cctcttgctc tcactttcaa taaaaataag
    17701 ttttgtattt tctaagtcaa tatgtactaa ttcatatcta gtaatagtac tttctctttt
    17761 attgcttgtt tttatctcat atactctatt tttttcgaaa ttagttattt caaccttaaa
    17821 tcttttatta tttttttgct gtacaaatgt tcctactgct tttttctcat taaaattagg
    17881 aaaatttagt cttgcagatt ttgtaaatat attaaatatg tcttttgcag aatattttaa
    17941 taaaacttca gttttaaatg tattcatatc gttttccctt ctgtatataa atttaatatt
    18001 tataagttaa tttttaagtt aaaatagtat aatatgccat attaaatcat gttaaaacta
    18061 tttatatagc taaaatctta cctatataag tatgtatact atcatataaa aataaaatct
    18121 taaaatagaa agggttaaaa acacagttta ttataatttt tattgttgag tagatacgta
    18181 ctattatata tgattgagca agtttttcaa tcataaattt ataaagtatt ttgcattaaa
    18241 atttaaacaa agaattaaat tatttaagat tatgaataac taatacattt agtaaattac
    18301 taaatataca aaatgtaaat acttatcaaa atgtataaat acttatgaca tctagttact
    18361 tacagggttt aagtagaaaa aaatatcaaa gtaagtatgg catgatagtt gcttatatat
    18421 ttatcaagaa aggagttatt aagcatggag ttgagagata aacttgtaaa catcataaat
    18481 acagaaaata aaaaagatcc attaacagat gttcaaatag caaagttttt aagtacaact
    18541 agagagaaca taactaattt gagaaaagaa cttaatataa gtaattcaag gcaaagaaga
    18601 tatccttatt taaaatcagc aatttcggca atattacaaa agaataagaa tatttctata
    18661 tcagaaatta caagggaatt gatgacagaa ggctttaata tatcgagaag agttgtggag
    18721 gaacttttac ctaaagaaag tttagaaatg gatgtagtag aggaagatga agaagaatcg
    18781 aatgacccat ttgaaactct gataggtaat aaagggagtc ttagaaatgc tgtagagcag
    18841 gctaaatctg ctatattgta tccaccaaaa gggttaccaa cgttgattat tggggaaagt
    18901 ggagttggta agagtttatt ttctagacat atgtatgagt ttgcaaagca aaaaaagata
    18961 gtaaaagaga gctccaattt tgttgtattt aactgtgctg attatagtga caatccacaa
    19021 ttattattat ctttgttatt tggatataaa aaaggtgcat ttacaggtgc tgaatatgat
    19081 acaccaggtc ttgtagaaga agctgatgaa ggagttttat ttttggatga aatacataga
    19141 ttgcctccaa aaggtcaaga aatactattt tctatcttag ataggggaaa gtttaggaga
    19201 ttaggtgaaa ctaatgctga aagaaaagta agtattatgt tgattggggc aactactgaa
    19261 aatgtagaga ctaatttatt attaacattc agaagaagga taccaatgct aataactttg
    19321 ccaccattac atgatagatt actaaaagag aaaatagacc ttatatacaa tatctttcaa
    19381 caagagtgta atagaataaa tgcaaaaata tttgtagata aaaatgtgat tgaaatactt
    19441 gcactaaaaa agtttagtgg aaatatagga caattacaaa atatgattca ggttctttgt
    19501 gcaagagctt ttatgaagtt tataaattcc aaagatgaag atagtgaatc tatagtagta
    19561 gtagatataa atgaagtttt aaagcttaaa gattcgttta aagatgctgc ctttcaagag
    19621 attgaatata cagagataag aaaatatttg aaaaatgcta tatttatacc atttaattta
    19681 gaagaatcat cagtaaaagg aagtctttta agtgatgaat atatattacc agaggacata
    19741 tacaaaacaa ttgaaaagaa atattatgac ctaaaatccc tagacattga agatatagat
    19801 atagagaata ttttatggac ttttatttta aatagatttg ctgacttaaa gtttaatctt
    19861 gatagtaatg aagaaatttt ttcaatgagt gatttaaata gttttgtaag tgatagttta
    19921 gttaaactgg taaaagaact tatgaatgat atagttgaaa aaaatatgaa tttagaagta
    19981 aataaaaata tgttcaaata tctagcaata cacttagaag aagctataaa aagaattaag
    20041 ctaaatcaaa agataataaa tgtaaattta gaaaaaataa agattgactt ttcaaaagaa
    20101 tatgaaatta gtaaaagttt tgcaataaaa attgaggaat caattggtat taagatttca
    20161 gatgatgaaa ttggatttat aacgctctac ataaagtctg ctctaaaaaa tgaagtgaaa
    20221 aaagataaag tagggttaat aataatttct catggacgta tagctacaga gactgtaaat
    20281 gtagttaaag aacttttagg tgtaaagttt cctgtggcta tagatatgcc tttagatgaa
    20341 aaaccaataa atatatacaa taaggcagta gaattgtcaa aaataataga ccaagggaaa
    20401 ggcatattgt ttttggtgga tattggttca cttacaaaca taggtcaaat agtaaataag
    20461 agaaccaata taagtactaa aactattgat agagtagacc tcctaatggc actagaagca
    20521 actagaaaag tttctatggg agaggaagaa cttgatgaaa tatttttttc tttgctaaaa
    20581 gataggatgg gatataacta tgaattagaa aaacacatag ataaatcaaa tgcaattata
    20641 acattatgtc ttactggaga aggaactgct aagtatataa gtaaaacgtt ggaagaaaag
    20701 tatgataaca ctaaatgtta tcaaatgagt gcattggatg aaagtttatt ttgtaaaatt
    20761 gaaaatctaa aagagacaaa caatatatta gctattgttg ggacaataaa ccctaagata
    20821 ccaggtataa attttatacc ctataataaa gaacttttca aaaatttgga tatctatcta
    20881 tcaaaatcaa aacaacaaga tgacagacca attaaatcgt atgaaagaat gcttgatgag
    20941 gatttagtga tttttgaacc agatatatat tttaaaaagg atttattaga atatgtatgt
    21001 tcaattctta taaataaaga atatgtagaa aaagattact tagattctgt tttacataga
    21061 gaagaaatgc ttccaacata ttctaaagga gctataggtg tgcctcatgg agattcttct
    21121 actgtaaata gtacaaggtt tgtttttgtt aaactaaaga atcctattga ttggggtgta
    21181 ggtaatgtaa atttcatatt tatgccagtt tttcaggcta atgataaaga gattgttaaa
    21241 aatgttcttg agatactaaa agatgcagaa tttatgaaca atgccaataa gtgttttgat
    21301 aaagatgctt ttagaaggat tatatttgat aaatttaaac atctgtagcc atagcaaaaa
    21361 aattgagagg agttagagta atgaatgtag atttaatatc attgggttta gaatctaatg
    21421 attatgaaag tgttattgaa gaattaggaa gtataatgtg taaaaaagaa tatgtaaaag
    21481 aaacatacat aaatgctgtc ttggaaagag aaaggacatt accaacaggt ctagatattg
    21541 gagacatgtg tgttgctatt ccacatacag attcaaagca tgtaaatgag tctaatgtag
    21601 ctgtagggat attgaaaaat cctgtaaagt ttaattcaat gatagaccca aaagatagac
    21661 ttgatgtaga acttgtattt ttattagcag taaagaaccc agactcacaa gtaaaactgt
    21721 taaaagattt aatgtcagtt tttcaaaata taaagttatt aaaaaatata aaaaacgcat
    21781 caacaaaaga agaagtagct aaattattgg attttataga aatttaatgt aggagaattt
    21841 tataaataaa aaattaaaat ttaaacaatc aaagtaagta ttattttttt aataggttta
    21901 atcttatata aaataaaaat ttagagtgaa aaattaggag gaaattatta tgaaacaatt
    21961 taatgtatta tcagtttgtg gttcagggac agttacatca tctatggtag caggtaaatt
    22021 aaaagaagta ctaggtaata aggggatttc tattactaca acagaagcta gaccaacaga
    22081 agcactaaat ttagcacaat caggaagatt tgactttata acatttacga gtccacttca
    22141 aacaggcgat tatggaatac caactataaa tgcatttgct tgcctaactg gtatagggga
    22201 agaggcattc tttgaagaag ttttgactgt tattgaaggg atagataagt aagttttgga
    22261 gacgtgaatt tatagtattt aaatcaatga tttagatact ataataagct aatattaact
    22321 aaatatttgt ggaaaaaaca ttttatatgt tgtcataaat taaaaaatta taaaaatagt
    22381 cacttaagta ttaaattaag cttataaata tttataagta ggagggaaaa agatgttaga
    22441 atttatgaaa tctataatcg atacatttgg ttctgcaatt atagttccaa ttataatatt
    22501 cataatcgca aagatattta aagtaactac taagaaatcg tttctttctg ctgtgtatgc
    22561 aggagttgct ttacaaggtt ttacactgat tttaaattca tttacaccag taataacacc
    22621 agttatcaat aggatggttg agagtacagg agtaaaccta ccagtttttg atgttggttg
    22681 gcaagcaaca tcattggttg cattttcaac aagtgcaggt atgatatatt taggtcttgg
    22741 tatattatta caaacaattt tatttttgat aaaatggaca gatgtgtttc aaccatcaga
    22801 tttatggaat aactattctt atatggtatg gggagcaatg gttataggag taacaggaaa
    22861 ttttccttta ggtatagcat gtatggtttt attaaaccta tatagtttat taatatcaga
    22921 gttagttgca aagagatggt ctagttacta tagatatcct aattgtacaa taatagctat
    22981 gcataatgtt gaggcttctg tgtttgcagt atttgcagac cctatataca ataaattggg
    23041 attaaataaa ataaaattaa atccaaaaga attagagaag aaattagggt ttttaggtga
    23101 accaattact ttaggtcttt ttttaggtat gtttataggt atattaggta atatgacgag
    23161 aataaatact atggaagctt ggggagaaat aatgaaagta ggtatatcta caagtgcagt
    23221 gatggcaatt ttccctaaag tagcaagtat gtttgctcaa gcatttgcac ctataacaga
    23281 agcagctaga aagattatgc aaaaagctgg aaaccgtgag tggtacatag cagtaaatga
    23341 tgctgttgga tatggtgaac ctgcaacttt aatatcaggt cttatattaa ttccaataat
    23401 gcttgtaata gctatggtac ttcctggtaa taaggtatta ccagttgtgg atttattggc
    23461 aattccatat atggttcaag gtttagttgc catacataat ggtaatatac caaaagtatt
    23521 agtttcaggt ataatttggt ttggattagg attatatgtt tgtacatcta cagcaccatt
    23581 atttacagat atggctacaa atataggtgt agctatacct gcaggagcaa tgttaataac
    23641 aagttttaat atactaggaa aacctttgat gggattagtt ttctttgcat ttctaagtgc
    23701 aaatccaatt tatataggtc tttcagttgt aatttacttt gttctatggg cattgtttag
    23761 aaagaacaaa acaagtattc ttgattattt agaaaaacaa gcacttaaaa atgtagaaga
    23821 agagcctgta gcagtttaag tttataaaaa tgaaataaaa ataattaaag gagtttataa
    23881 ttgattttat ataagtatca gataatacct gagaaatatt taaatgaaat atagacttct
    23941 ttttatttga taatatttgt aattataatg cattgtattt ttatagttga gttttctgta
    24001 taacctgcta tttaaaacat actcttttat atttatacag taatgtggtt taattttata
    24061 aaatgtaatc tctactggta aaagactttg tatataaggc atttgcctga ataaaccatt
    24121 tatcttttgt atggcataga tattgctata tagaagtata tagcatgaaa ggagatattt
    24181 atatgggaaa taaaatgaga gcatcagtat tgtataatgt aggtgatgtc agatatgaaa
    24241 tggtaaatat accagaaata acagatacgc aagtgcttgt aaatgtaaaa tatgttggga
    24301 tatgtggttc agatttacct aggtctatgg taagtggttt gagtggaaat acaaaatatc
    24361 cattgatttt agggcatgaa ttttctggtg aagttgttaa aattggagaa aaagtaaagc
    24421 atattaatgt aggagataga gtagctgttg caccattagt accttgtgga aaatgtgatt
    24481 attgtaatga aggtaatttt ggcttgtgtg atgattacaa tataattgga acaagagtaa
    24541 atggagcgtt tgcagaatat gtaagagttc cagaagaaca tattttaaaa ctaccagata
    24601 cattggatta tgaaactgct gccggaattg aaccagcaac tatagcttat catgggattt
    24661 caaagtctaa tattagagta ggagatagtg tagttgtgtt aggatgtggt ccaataggtc
    24721 agtttgttat acaatgggca aaggtgtttg gtgcatctaa gattatagca gttgatattt
    24781 ttgatgaaaa attagaactt tctaaacttc taggagcaaa ctatatactt aactcaaaag
    24841 aagtaaatgt aatcaaagaa ataaaaaaaa taacaaatgg tggtgctgat gttgtaatag
    24901 aaactgctgg tagccgattt acacaagaac aatctctatt tgtagcaaaa aagagaggaa
    24961 atatagtgtt tgtaggtata tcacacacag aattaccact tagtgcagac gctactgagt
    25021 gtatattacg tggagaactt accttgaaag gttcttggaa ttcatataca agcccttatc
    25081 ctggaagagc atggactgca acattggatt ttatggaaaa aggtgacatt atttttaaac
    25141 ccatgatttc agataaaata ggtcttaatg aagtgggtga ctttttaagt aaaatgagca
    25201 agagagaaat taatttcaat aaaatcctag tagaaatata aaaatttaat aaaaaattct
    25261 aaaagcaatt aaattttata actatgacat taaataaaat aaaaataatt ttcttaaata
    25321 aaatatagga ggaagaaaag tgttagaaaa tttaaaagaa gaagtattaa aagcaaactt
    25381 agaattacct aagaaaaagc taattactta tacttgggga aatgtaagtg ggatagatag
    25441 agaaaaagga ttagtggtga taaagccaag tggtgtagag tatagtaata tgactgtaga
    25501 agatatggtt gtagttgatt tagagggaaa tatagttgat ggcaaattaa gaccttcttc
    25561 agataccccg actcatctag ttttatataa agagtttgaa gaattggggg gaatagtaca
    25621 tacacattca agttgggcaa caatttgggc tcaaatagga aaatctatac catcttgtgg
    25681 tactactcat gcagattatt tttatggaag tataccatgt accagaaaaa tgactagaga
    25741 agaaatttgc aatgaatacg aaaaggaaac tggaaatgta atcattgaag aatttatggg
    25801 aagaaatcca attcattgtc caggaataat tgtaaatgac cacggacctt ttacatgggg
    25861 aaaagatgca aatgaggctg tacacaatgc agtagtttta gaagaagtcg caaagatggc
    25921 ttattataca gagttaatga gtcctgataa tattatggat aaggttctta tgaataagca
    25981 tttttcaaga aaacatggaa aaaatgcata ctatggtcaa aaatgattat ctggaggtga
    26041 attatgctag actctttaaa aggtaaagtt gtggaaatag caattaaagc agagcattat
    26101 ggtttatgta aagaaaagac tggtaatttt agtattagag ataaggatac tggatatata
    26161 cttataaccc catcaggtgt aggaagagaa gaattaaaag ttgaacatat ttgtgtattg
    26221 gatttggatg gaaatgtaat agaagttgag aaaggtatta agccaagtag tgaggtattg
    26281 atgcatattg aaatatacaa aacaagagaa aatataaatg ccatatcaca tactcattct
    26341 ttatatgcaa cagcattttc agtagcaaag aaaccaatta taccaattgt atatgaatca
    26401 gttaattatg gcggttatgt agatattgct tcatacgaaa gaccaggaac tttaaaatta
    26461 gctaagagtg tttcaaaatt actgatagat acagatgcat gcttattaga aagacatggg
    26521 ttgacaactg taggtaatga tttagacgaa gcattattaa aatcaagata tgtggaagag
    26581 gtagcagaaa tatactatag gtctttagta ttaaatcaat ttaaagaact tgaagtagta
    26641 gatgttgatg agtttaaatc ttggaaatac ccagaagaaa taaagtttta atctaaataa
    26701 ttttcattga agtggttaat taaaatatat gtattattta tatcaattac tatgttttat
    26761 tatgttaatt accgtatttt gcaaatatat ttattacatt ttttcaaaaa aatatagaat
    26821 ccgaaagcca tataaaattg acttgggatt ctatactttt tatttatgca tttttcttta
    26881 tctgattttc tggagaattt atatgttcaa aatatttttt agtttcagat actattatag
    26941 gtgataatgc aagtaaagct ataaggttag gtattgccat aagcccattt acaatatcag
    27001 caattatcca aacaacttct aactttaaga aagcacctaa taacaccata gccacaaata
    27061 cagttctata cccattcatg ccttttacac caaacagaaa ttcaaaacat ctttctccat
    27121 aataactcca tcccaaaatt gtagtaaatg caaataatgt taaactaact gtaagtaata
    27181 ttggtccaaa tgtaggaatt gctccgttaa aagctgcttg tgtcataaca gctccattta
    27241 ggtctgaaca ccacactcct gaaataacaa gagagaatcc agtaagagta cagattataa
    27301 tagtatctat aaaagtacct gtcatagata taagaccttg ttccgctggc cattcagttt
    27361 tagcagcagc tgcagctatt ggagcactac ctagaccaga ctcatttgaa aatacaccac
    27421 gagcgatacc atttctaatt gccagtgaca tagttgctcc taaaaaacca ccagtagcag
    27481 cagtaggtgt aaatgcactt ttaattatta acataaaagt ttcagggatt ttattccaaa
    27541 aagatattaa aatgattcca cagattacaa catatataac tgccataaaa ggtactattt
    27601 tagtagctac attagatata cttttaagtc ctccaaatac aactaaagct acaaatactg
    27661 ctaatacaac ccctgtaatt ctagggtcta tcccgaaact attatttatt gcatctgtta
    27721 ttgaatttac ttgagtaaaa gtaccgattc ctaaaagtgc aactagtata ccacttatag
    27781 cgaaaaatat tgcaagaggt ctccattttt ctcccatacc atttactatg taatacattg
    27841 gcccaccaga cacttgacca tttttatctt tagttctgta ttttattgca agaacacctt
    27901 ctgaatactt agtagccatt ccaaagaatg ctgctatcca catccaaaaa agtgcaccag
    27961 gtccaccagc tttgatagct gtagcaacac caacaatatt accagtacca actgtagcag
    28021 ctagagcagt acataaggct gcaaaacttg aaacatcacc actacctttg ttttcagcag
    28081 agaatattaa cttaagagct cttggcagtt tagttatttg aacaactcca agcttaacag
    28141 taagtagtat accagtacca actaatagta ccagtagggg tggtccccaa ataaaagcat
    28201 caactttgtt taaaatatca attagattca taaaaacact ccctcatttt ttttgcttta
    28261 cataatcaat agaattttta atgaagtaat tgacaggaaa taagtataat ttattaataa
    28321 tttctagtgt aataaaaaaa gctaaatcta aaaaagattc agctctggat gtacactaat
    28381 tagcaaccaa aataaaagta ttagtaaata ctgtttttgg tagataatcc ctgtcctttt
    28441 gcctgagaga ttgagcataa aagccttgcc ccttcggcgc ccataatggg tctctccaga
    28501 gttccgtaaa ttttacagtc ctacttttaa aagtacctga gagtgttact ccttcggtgt
    28561 gctatatagc aactcttcta taaaatctta accggatatt gatttgtcat agcttattgt
    28621 attaataata ttaatataag tttttatgtt ttgtcaacta aaaaattaaa aaacaaagaa
    28681 aaaatataaa aatgtaagcc tatttacgaa ttataaactt agaaagatga gtaatatacg
    28741 tgaaaatgaa ttttgtaata cacatacaaa tgaagtgtaa aataagtttt aaataaaaaa
    28801 ataataaaat cttaaataat taattagata tgattaaatt atggtaatat tatagttacg
    28861 atattaagaa aagttctatt tagttagatt ttaagcgtaa tatgagatta tgtatagaga
    28921 aaggatgtat ttttagatgg gaaaaatatt agtgctagca gaaaaacctt ctgttggaag
    28981 agatatagca aaagttttag ggtcaaaaaa tgaaaaaaat ggttatatag aggggccaaa
    29041 gtatgtgata acttgggcac taggtcattt ggttacactt gctgaccccg aaagttatgg
    29101 agaaagatat aaatcatgga gcttagaaga cctgccaata cttcccaagc accttaagac
    29161 tgttgtaata aaaaagagtg gaaagcagtt taatacagtt aaatcgcaaa tgaatagaaa
    29221 tgatatagat gaaatagtta tagcaacaga tgcaggtcgt gaaggagaac ttgtagcaag
    29281 gtggataata gaaaaatcac aggtaaaaaa acctataaaa cgtctttgga tttcttcaag
    29341 tacagacaaa gcaataaaag acggatttgc aaaattaaga agtggaaaag aatatgaaaa
    29401 tttgtattac tcagcaatag cacgagcaga agctgattgg attattggaa taaatgcaac
    29461 cagagctttg acaacaaagt acaatgcaca gctttcttgt ggaagagtac aaactcctac
    29521 tcttgcaatg ttgcttaaaa gagaagaaga aataagaaat ttcaaaccta aagagtatta
    29581 tggattagaa ttaattgcta caaagggaaa ttcagatata aaatttattt ggaatgataa
    29641 aaacaataat tcttcaactt ttagtaaaga aaagatagaa tccacattaa aaaaagtaaa
    29701 aggtgtagac ataaaaatat ctgaagtaaa caagtcatat aagaaaaaat attcacctgc
    29761 actctatgat ttaacagaat tacaaagaga tgcaaataaa atgtttggat tttcagcaaa
    29821 agaaacttta tctataatgc aaaaactgta tgaacatcat aaagtactta cttatcctag
    29881 aactgattct agatatttaa catcagatat tgttggaaca ttaaaagata gaataaaagc
    29941 tgtaaatatt agtgattatt caaagatttg taatagatta ttaaaaagca atattatagc
    30001 taataaatcg tttgttgaca attcaaaggt aacagaccac catgcaataa taccaacaga
    30061 acagaaggta ttcatgagtg attttagtga taaagagcga aaaatatata atcttgtagt
    30121 aaaaagattt ttagcagtac tatctcctcc ttttgaatat gagcagacaa ctataagtgc
    30181 aactgtagaa ggagaaatat ttaaggctaa gggaaacaaa gtaataaatt taggttggaa
    30241 agaaagttat aaagatattg aagatgaaga tgagtatgaa agtataccaa atgttttaga
    30301 aaaagatgta cttaaggtca agggattaaa gataacttca ggaaaaacaa atccaccacc
    30361 atacttaaat gagggaacat tattgactgc tatggaaaag aatggtctag ggacagttgc
    30421 tacaagagca gatataatag aaaaattatt caattcattt ttaatggaaa agaaaaataa
    30481 agatatatat ataacatcaa aaggaagaca attattagat ttagttccag tagacttaaa
    30541 gacaccagaa cttacagctt catgggaaaa gaaattattg gatatttcaa agggaaaact
    30601 tagtaaaaat acattcataa atgacatgaa agattattca aaagatattg tactagaagt
    30661 aaaaaatagt gataataaat ttaaacatga taacttaact aaaaatagat gtccagaatg
    30721 tggtaaattt atgttagagg taaatggtaa aaaaggtaag atgttgattt gtgaagatag
    30781 agagtgtaat actagaaaaa ctatatcaca agtaaccaat tcaagatgtc ctaactgcca
    30841 taaaaaatta gaacttcgtg gagaaggtga ggggagactc ttcacttgta gttgcggata
    30901 cagagaaaag ttgtcttctt tcaacaagag aaagcaagaa gaaaaacaga aggcatcaaa
    30961 aaaagatgtt aatcaatatt taaaaaatca aaataaaaat caagagacat ttaataatcc
    31021 atttgcagaa gcattagcta agctaaaaaa caaataattt taaagttatt attatacaca
    31081 attataactt taactgtata ttagttatat gtactgatat aatatagtgt atagtttagg
    31141 catgaaagta gggctgttaa atggatttaa gtggcatatt taaatactat tgtaaagagt
    31201 gtgaaaatac atggaataat tcgagtgttg aattatttga gaatatagaa acgtatagta
    31261 aagattcaca aaaaaagagg gaaaaagaat tagataaatt gctaaataca atatcagttc
    31321 atttagagag gtatccaagt gatgctgtat tgagaaaaat gtgggtaaaa aagggcgagg
    31381 ttttcttaca aaagacattg gaaaaagaaa atatttttaa gttagaaaaa atggatgtag
    31441 aggatagaaa aaaattttta gatataacaa aacagtttat tagagatgct agaaaatttg
    31501 atgatgattt acctataggt gatattatgc aagctatgag gaatgtatgg atttcaaatg
    31561 cattacaatt attatttggt aaagaagtat attattcaaa agctaacttt gcatatagta
    31621 tgttatatcc atatactgat aattatttag acaatacaaa tatagataaa aatgataaga
    31681 ttttatttaa taactggtta gaaaaaaggc tcctgggaga acacattaaa tctaaggatt
    31741 atcatgaaag taaagtatct caaatgatag attatattga aagtgtatac cctagagaaa
    31801 agtttacaga agtttatgaa tcgttattat taatatttaa aagtcaagta aatagtttaa
    31861 aacaacatgg taaggaaaat catttgtgta aagaagattt attatccatt tctattgaaa
    31921 aaggaggttc atccgtttta gtagatggat atttaataag tggattgatg acaaaggaag
    31981 aaatagagtt ttgtatagga tatggatttt tattacaaat atctgatgat ttacaagata
    32041 taaaagaaga tttaaaatac aaccataaaa ctattattac agagatgtca aaagagggta
    32101 ctttagataa agttgtaaat aaactaataa attttactat tgagttaata gatagtttta
    32161 aaattaataa taaaaataaa tctgtaatag ctatgataaa gaatgattgc ttaatgttaa
    32221 ttttattttc tgtagtttat aatgctgaat ttttttctgt aggatatata aaagaagtag
    32281 agaaatttat tccatataca atagattatt cattagagat tgaagaaaaa ataaaagaaa
    32341 aatttaaaaa tatagatgtt ttaaataatg aaaatgaata taaagaaatg attgatatta
    32401 tttgtgcaga gtagaaaaaa agggagtgtc ttagaataga ctttttagtt tatgaggcac
    32461 tctttttgta taaaatcaaa tgtattttca tcattttaac aattaaaaag agcttatccc
    32521 tatttgagaa agcccttttt aatttaaata aaaatgtcaa ggttaaacta tttaaatgca
    32581 gtaataatcc cattatcatg taagtttttt atgattgtag ctgcgatagg gaatccaaat
    32641 aatccagcta ttccaaatag ttgagctcca acaaacatac acattaatgt tattaaagga
    32701 tataggccaa tttggtgtcc tactaccttt ggttctaata tttgtctaac aacggttata
    32761 attatgtata gtattaaaag tcctattgct aaattaatat ttccattaat gagtgagata
    32821 atcatccaag gtgtcaaaat acttcctgta cccaagactg gcaaaatatc aacaagtgct
    32881 atgatgacag atatagtaaa tgcattttca acctttagga tagtaagtcc aataagtagt
    32941 tctatgaatg tcactgatag tagtattgca taggctttta gtagttttaa aagagcatta
    33001 atactgctat tttttatatt tattatcata aattgacttt tttctggaaa ttgttttaag
    33061 ataaagttta ctattttttg atagtcaaaa gtaaagaaaa aagaagcaat taaagtaata
    33121 ataagtttta acataaatgc aggtgtttta cttgcaatac tagcaatagc attgagtgca
    33181 tttgttgaaa tagaagctac taaagacatc atagattgac ttatattatc ccaaccaagt
    33241 attaatgcta ggttaacatt aggtgtacta gcatctatct ttgaaaataa agtatttagc
    33301 gttggttgta tacttgattt atatatttca ggaagtctaa aaaatacatc acttacactt
    33361 gcaaatatct tcacaccaaa gctaactaat aaaaatatac acaacccata aaaaattaaa
    33421 agtattacta tagaaataag tgtacgattt aaatttgtat tatttgtaat aagtcttata
    33481 ataggtctta agatggatgc aatgataaaa ctgattacaa aaggcattaa taatggcaat
    33541 aagaatttta atacaatata tacaatactt gttattaaaa ctacatatgt aaatttaatt
    33601 ataaaattct tttgcttttg aatatccata atataaaacc tccaatgtat ttgatattat
    33661 tctaaatatg gtctttttta cagaaaatat actactgtat attgattata aactataaag
    33721 cttatgtaaa gtaaataaat tatgtaaaat ttaggttaat tttgtataaa gagatacttt
    33781 tatattttac aattaataac caaatactaa aaaatatttt aaataaagaa cttaaaattg
    33841 tgataaaatt aatttataga tattaaaaaa agtataatat atggttttta agaggtgcta
    33901 agatgaaaaa ttttagagat ttaggtggga acaaaactga ggatggcaga actgtaaaga
    33961 agggattatt ttataggtct gcaaaattat caaatctaag tgaaaatgat ataaagattt
    34021 taaaagagtt aaatattaaa tatatatttg attatagaag tgatgaagaa gctcgtaaac
    34081 atccatcaac aataatatca aatataaaaa atataagaat accagcaatg agagagctag
    34141 aagaatcagg aggaagtttt ggttctattg aagatatgat tgatggattg tttgaaaaag
    34201 atggtgcatt taatatgtta aataatagtt actataattt gcctataaat aatccgtcat
    34261 ataaaaaatt agtagaactt ataagagact attctaattt accaatatta aatcattgta
    34321 cagctggtaa ggatagaact ggtgtgggga gtgctataat tcttatgatt ttaggggtat
    34381 cgagagagaa tataatgaaa gattatctaa aaagtaatga ttttgcagat aaagagatag
    34441 aaagatttat agaatataag cctaaattta aggacattcc aaaagaaaat ttgaaatata
    34501 tatttggtgt aaatgaagag tatatgaaaa ctgcatttag aagaattgat gaagaataca
    34561 ttagtgtaga agcatattta tatggagaat ttaatttaaa taaagaagaa ataagaaaat
    34621 taagaaatca atatctagag taaaaggtga gtttatgagt ttaaatataa cagcaagaca
    34681 gataaatata ataaaaatat tgttaaattc aaaagataca attagtggta ttgccttaag
    34741 tcaagagata ggatgttctt caaaaactat acaaaatgaa ataaaggata ttaataaaca
    34801 acttagaaat ggtaaaattt tgtcaataag aggagttggt tataaactag aaggaagttt
    34861 tgatgaggta aatctaaata gcaatctcta tgatgatgta gatagagtag aatatataat
    34921 cagaaaaata ttaaccttaa gtaatgaaga aaaaaatact ataaaacttg aagatttagc
    34981 cgattctatg tatgtaagtg tttcaacagt aaaaaatgat ttaaaagaag taaaaagaat
    35041 gttggaaaag tattcaatat cagttaaatc taagcataaa caaggtatat gtgttttgga
    35101 aagtgaagat aagatattaa attgtatagt tgacttaagc aataagagag ataatcaatt
    35161 gagtttaaat gattttttaa atgatgatat aaaggaaaga aaactattaa taaaaaaatt
    35221 attattagac atattaaatg aaaatggatt agtattaact gatatagaat ttaagagtgt
    35281 gttaaataat atattagtta tgttaagcag acataagtat aatgaaaaag aatttataga
    35341 gaattatata gaaaattata ggagcaaaag aagctcaatt ttagaaaatg aacaaaacaa
    35401 agaaattata ataaattcaa taaaaacatt ttgtaaaaat ttaaaattag ctacatcaat
    35461 agatataagt aatgataagg tatttgaaga gtttttgtat aagcatatta gtagtttatg
    35521 taaaaaaata aagttaggta taaatcaatc acctataatg gctcaagata taaaaataaa
    35581 atatccattt gcttttgaac tagctaatat agctaaaaag acaatagaaa aagatttgaa
    35641 gatagaaatt aatgaagatg aagttgcaaa catagctcta catataggag gagcagttga
    35701 aagagcatct tataataata aagataaggt tttcaaaact ataatagttt gtacttcagg
    35761 cataggcaca tcaatgttaa taaaagctaa attagagaat atatttaagg aaaaattaga
    35821 aatactaaag attattcctt catacttagt tgaatatata aaagttatag atgttgattt
    35881 tgtaatatct actgttccta ttgaagtagg agatgtgcca gtaataaata tatctccaat
    35941 tttaagtgag aaagaaatta gattaattga aaaatatata gaaacaggaa atatatacct
    36001 agatttagat ataaaaagcc tgtttgatag tgaattgttt tttactgatt tggtgtttaa
    36061 aaggaaagaa gaagttatag attttatggc aagtaaactt gtacaaaagg gctatataga
    36121 tgaggatatg aaaaaatctt actttgagag agaaaaaata gcaacaacag aaatagggaa
    36181 tatggtaact ataccacatg gagctattgg aaaaattttt gataataaaa tagcaattgg
    36241 tatattaaag aagcctattt cttgggaaat atcagatgtt cgtttaataa taatgttagc
    36301 ccttgataaa gataaaatat tagattatga agtaatattt tcaaaaatat ataaaagagt
    36361 agattctata gcaaaagtta taagtatatg tgaaaatagt agttttgaaa aatttgtaaa
    36421 tttattcaat tagatgggta gtattgtata tacacctgta aatttggata atataaaact
    36481 aaataagata aaaacgataa atttctcttt taattaagag aaattttttg actttcaagg
    36541 atattaatat aaagttaaga tataaacata aagcaaataa ataaaaaaga ggtggcaata
    36601 tgatttatac agtgacatta aatccatcaa tagattatat agttaagcta gatgagctaa
    36661 agacaggaag tacaaatcgt gtaaaagaag aatacgttta tccaggagga aaaggtataa
    36721 atgtatctcg catatttaag gaacttggaa atgataatac atctttaggt tttataagtg
    36781 gttttactgg agaatatata ataagaacat tggaagaaaa agaattgaag acagatttta
    36841 taaagataaa aagtggtttt tcaagaataa atgtaaaaat aaaggcgtta aaggaaactg
    36901 agattaatgg acaaggtcca aatatagatg atgaagacat tgatacttta tataaaaaac
    36961 ttgataagct aaatcaagat gatattttaa tattggcagg aagtatacca tctactttag
    37021 atgaaaaact atacgaaaat ataatggcta gattagaaaa aaagaatata aaagttgtag
    37081 tagatgcaac taaaaatctt cttcttaatg ttttaaaata taaacctttt ctaattaagc
    37141 ctaataacga cgaattagaa gaactatttg gtgttaaatt aaattcaatt gaagacatgg
    37201 taaaatatgc tagaaggtta aaggaaatgg gagctataaa tgtcttggta tcaatgggaa
    37261 aagatggagc attgttgatt acagaggaag atgaagtgct tataagtgat gttccaaaag
    37321 gaaaagtaaa aaattctgta ggagcaggtg attcaatggt agcaggattt atatctgggt
    37381 atttgaatac tgggaaatat gattatgctc ttaaattggg agcagcttca ggtagtgcaa
    37441 ctgctttttc atatgactta gccaaaagag aatacattga taaattggta aatgagatat
    37501 ctgtaaagca gttttaaaat attaaaaaat atatagaaag gtaattaata tttatgaaaa
    37561 ttatagattt attagatgaa aagtcaatta agttaaattt aaattcaaaa accaaatcag
    37621 aagcaataga agaattagta gatttggtcg caaatagtgg aaatttaaat gataaagaaa
    37681 actacaaaaa agcaattttg gctcgtgaag aaatgagtac aacaggaatt ggagaaggtg
    37741 tagctatacc tcatgctaaa aattcttcag ttactaaagc ttgtatagca gcagcagtgt
    37801 caaaagaagg tatagattat gaatcgtttg acggaagttt atcaaatcta ttttttatga
    37861 tagctgcacc agacggagct aacaatactc atcttgaagt attatcaaga ttatctacaa
    37921 tacttatgga tgaagacttt agaaataaac ttataaattc aagctctgaa aaagaattta
    37981 aggaaataat agataaaaag gaaagagaaa aattcagtga agaatatcaa gatgagaaag
    38041 ttactgaaaa aaatataata gatactaaag agaatgatgc taataagtat cctaaggttt
    38101 tagcagtaac agcatgtcca actggaatag cacatacatt tatggcagct gaaagtttaa
    38161 ataaaatggc agaaaacaaa ggtgtatcaa taaaagtaga aactaatggt tcagcaggtg
    38221 ttaaaaataa gcttacaaaa gatgaaatag aaaatgcaac atgtataata gtggcggcag
    38281 ataaaaatgt tgagatggct agatttaatg gtaaaaaagt cataaaaact aaggtggctg
    38341 atggtataca caaagcggaa gaacttatag acaaggctgt aaatggagat gctccaattt
    38401 accatggagg agatggaagt cacaacgaat caaatgaaga aagtgaaagt ggatttagaa
    38461 aagtatacaa acacttaatg aatggtgtat ctaatatgtt accatttgtt attggtggag
    38521 ggatacttat agcgatagcc tttttacttg atgattatac tattaaccct tcaaactttg
    38581 gttcaaatac acctatagca gcatttttta aaggaatagg agataaagct tttggattta
    38641 tgttacctgt acttgctgga tatatagcat actctatatc tgatagacca gcgtttgttg
    38701 taggatttgt aggaggtgct ctagcaggtg atggtggttc aggtttttta ggtgcactac
    38761 ttgcaggttt tatagcaggt tatttagtag aagggcttaa gaaaatattt agtgtactac
    38821 cagcttcatt ggaaggaata aaaccagtat tgttataccc tttacttgga acacttttga
    38881 tgggaattat aatgacattt ttagtaatac ctccagttac agcaattaat aatgcaatgg
    38941 ttggattttt aaatggttta ggtggaactt caaaaatagt tttaggatta gtattaggtg
    39001 gaatgatggc tgtggatatg ggtggacctg taaataaagc agcatatgta tttggagttg
    39061 catcacttga atcagggcag tttgaaataa tggcagcagt aatggctggt ggtatggttc
    39121 cgccacttgc tatagctctt gcaactacat tttttaagaa tagatttact aaagaagaaa
    39181 gagattctgg taaagttaat tatgtaatgg gattatcatt tgttactgaa ggagctatac
    39241 cttttgcagc tggagaccca cttcatgtta taccagcttg tgttggaggt tcagcagtgg
    39301 caggagcact tagtatgttg ttcaacgcag ctcttcgtgc acctcatgga ggagtatttg
    39361 ttataccagt ggttacccat ccatttgcat atatattagc tatagctgta ggtgctttgg
    39421 ttggaatgat gcttttagca ttacttaaaa aaccattaaa tcaagaagta tagcaattaa
    39481 aggatattca agaacttaaa atatgatgtt ttataaaaat taatatattg ctgaattatt
    39541 ttaaaataag gattttatga ggctgttata taacgatttg taattgttat cttgacagtc
    39601 ttttattttt atataagtaa aataagtgtg ttttgcttta tttgtattta aattgttttt
    39661 aagttagaat ataaagaaaa ttatatatta ttttaatatt cactcgaact agaaaataat
    39721 atttgttgta tttttttgta tataaaatat attgtaatat taaaaaaata atagtaaact
    39781 gattgcataa aaatgatttt tatataaaat ttaagcagaa gaataaattt ctaacgaaat
    39841 tggatatttc ttctgtaaat acatattcaa aaaaagaatt ataagagttt agtcagcagt
    39901 cgtgtaagta ataaggactt tataaatata tagaaatata atgatattaa tataaccaag
    39961 cgatttttaa tttagctttt taataagctt attttttata ctatttataa taaataaact
    40021 ccatgatggg aaaactatta ctatttaata tgtaaaggag tattttaaat gaatgaatca
    40081 tattggtttt taaactcaag tccaaaagaa tataacaaat taggtgaaaa tataaaaaca
    40141 gattgtctta tagtaggtgg tggaataacg ggattgacaa ctgcatattt attagcaaaa
    40201 gaaggtaaaa aagtagtgct tgttgaggct gataaaatag gatatggaac ttctggaagg
    40261 aatactggta aggtaacttg tcagcatgat atattttact ctaagataga gaaaaaatat
    40321 ggattagata aagcaaaatc atattataat gcaaataatg aagctttaaa tttagttgaa
    40381 caaataatag aagaaaacaa tataaaatgt gattttaaaa gggaaacttc ttttgtattt
    40441 acagaaaaag aggatactat aaaggatatt aaagatgaat atcgtacatg taaaaaaata
    40501 ggaataaatt gtgagtatca tgaaactata gaaaatattc cattagatat aaagggggct
    40561 attagtttta ctaatcaagg tcaatttaac ccaaagaagt atattgatgg attggcaaaa
    40621 gcagcagtaa atttagggct aaaaatatat gaaaatacac cagtagtaga ccttgaaaaa
    40681 ggaaaaatat gtagggttaa aacaagagag gataatataa tagaagctga gaatgttata
    40741 atttcatctc atagtccatg gtatgatgga ttgaattttt attttgcaaa agaatatgca
    40801 gagcgtgctt atttaatggt tgcagttttg gaaaataaat tagcagatgg tatgtttata
    40861 agtatagatg acccatcaat aacttttaga caatataatg atggaagtga aaatttactg
    40921 atttttggag gaggagacca taaagttggt cagggaggaa ctgagaaaga aatatttgat
    40981 gatttagagc attatggtaa agaagtcttt aaggtaaaag attttaaggg gaaatggtct
    41041 gctcaagata atatgagttt tgacaatgtt ccttatattg gttatatcaa caaaagagaa
    41101 gacaatattt atgtagctac agggttctct aaatggggaa ttactaatgg aactgctgct
    41161 ggaataataa taaaagattt aataataaat aataattctg attataaaga tacttttaat
    41221 ccatccagac taggtagcta cttttcaaaa gattttataa aggaaaatgc aaacgtagca
    41281 ataaattatg taagtggaaa attaaaaata ggtagtggag atatgcctaa aaataatgga
    41341 gaaggaaaga ttgttaatat tgatggaaaa agatatggtg tatataagga tgataatgga
    41401 gatttttata ttgtagacac tacatgtact catttaggat gtgaacttaa ttttaacagt
    41461 gaagaaaaaa catgggactg tccatgtcat ggttctagat ttgactataa gggaaatata
    41521 cttgaaggac cagctcttaa gccattaaaa ctttatggac atggtgataa tgatgttaat
    41581 cctaagttat tataaaatta tttttaggaa ggtaaagtgt atatgaataa acttttaaag
    41641 ccaataacta tactattgta tatagtttat attttatctg ccgtattttt tgtagcaaac
    41701 aaagaatatg gaagtctagg tctagtagca attagtttag ttggtacttt cattttgagt
    41761 tttataaata agcaaactga aagattattg agtaaagaat tatatataat gcttgcttta
    41821 tttataatgt tttcatcatt gttaggtact tgttttaatt tttatgatat aaattattat
    41881 gatgattttt tgcatttatg gtcaggtata atatcttgta ttgtggcttt ttctataatt
    41941 aaatactttt atacacaaag agagataagt aaaatgagta aagtgttttt agttatattt
    42001 ttatttatgt ttagtatggg agtagcgagt ttatgggaaa taggtgaatt tttaatggat
    42061 acttttgttg ggactactac acaggccgga gggttagaag atactatgat tgatatggta
    42121 gatgctttaa taggcacaat tataactatt ccttttatag taaaaaaatc taatatatag
    42181 ttttaaattt tttatattaa ttataatgga tttaattaat catgttgagt ttcaaggtct
    42241 atatgattaa ttaaatccat ttttgttatt tataattatt attgaatata tttttacata
    42301 taagatataa ggtgatagat agaaattgtt ggattatgta aataattaat atataatacc
    42361 attatgggca ataaatacaa atcaaatgat aatatagtct atttatgtaa atgttatatt
    42421 gtatcctaag tataatagta agttttttga tagtggtgta gaaagtaaaa atctactagc
    42481 ctaaattgat gtatggatta gtttaggaac agtaattgca tatcttaagt ttgatgtcat
    42541 gttgggctac tagaaatagg tcatcttttt cacttgaata tcttttcttt aaacatgggg
    42601 agtatcatat caaaaacata tgaaaattaa gtgatttatg agaacagtaa tattttatat
    42661 gatagtatag aatagtaata aagtattagg aggaacattg agtgttaaaa aagtggtttg
    42721 gtattgtgaa aaaaagacaa aaaagtgagt cagtaaaaga agaaggtgaa gtaatattaa
    42781 aaaacgaaaa aatattatct gaagaaaagt tgatagatga agaaggagtt gtagttaata
    42841 ttgataatca aatattaact aaagtagtaa atgatgacaa tgaaatagaa gaaaaaataa
    42901 tagaagaaga tttgttaatt agtgaaaata ccataaaatt agatgataaa gaagcaatta
    42961 ttaatgataa aaacatagaa ttatgtaaaa aagaagttca agttgaaagt gaaaaaatag
    43021 gtttaaataa gtttgaagga ctggaccaaa atgaaaatta taatctagaa aaaaatgtta
    43081 ttgaagaaaa aaaagtaagt gaatgtttga cagaagaaga tttagagtac ataaaagaaa
    43141 ttaaaataaa aagaggaaaa agtataaaag ctataaactt gtatactaaa gaagagtggg
    43201 tttttgacac tcatatacag tgtagtaaaa aactcaaagt tccattaggg tacataagag
    43261 aaaatttaaa atatggatat atggattact ttggagatgc aataaattat ttaagtgaag
    43321 tattaaatat agatgaatac tgcaaaagtg aatggagcta tctcgataat agcaaatctc
    43381 catctgagat atttaatatt ctaaacaata aaatatttag tataaggctt tctaatgaaa
    43441 aaagaaatga aattttgaca aatgataaaa ttgaagcatt aaaaatgaat tatagatttg
    43501 aatgtattga tgaagaatat gatgaatatt ttaaaaaata taagtctata atcaaaagag
    43561 gtggaaagaa aaaagttgaa ttagtaaata aaaaaggtga cattttagaa atatttaagt
    43621 ctttagaaga atgtgccatt tatttgcaaa aggaaaagaa tgaagttata caaatgttaa
    43681 aatatggaga tacaaaagta ggaagaaact ttataaggta tagtttgaga agtatttaat
    43741 ttcattttaa attcataaga gtttcatttc tgattcacac atttaatatt attttaatgt
    43801 aaaataataa aggtgaagta ttgcacaatt aaaattaagg agggtattaa tgtctgaaga
    43861 aaaaaatcca aaagaaaata cattagatga atctaaaaat tcagataatg taaattctaa
    43921 aaaagatgat gtgtcagatg aaaaaaatac tgataacaaa gttaaaaaaa gggaaataaa
    43981 gctaaacaac aaaacactta aagctattgt agcaattgtt gcagtaggag ctatatgttt
    44041 aggtggaggc tatgtttttg gcaaagaagc tggaagaaaa ttgcctgcta cttcaaaaca
    44101 ctataatagc agtgaggtag tagctactat tggggataaa aaaataacag gtgaaatgtt
    44161 aagaaagaga atggagccat tattttattt aaatgcaaaa actactatga ctgatgacga
    44221 aatacgttca tatgaatcaa atatgattga aactatgatt acatctgata tattatcctc
    44281 tgaagcagca aaagagaaaa taagtataac taatgaccaa ctagatgctc agtataataa
    44341 tttaatgagt agtatagaat cagcaatggg aatgactaaa gaagagtttt taaaacagtt
    44401 tgatttgact gaaaaatata taaaagatga tatgaaaaaa gagctagtag catcaaaata
    44461 tttaaatgaa aaatcaaaag ttactgataa agaagcagag aactattaca ataaaaacaa
    44521 gagcaattat ttacaagtta gagcttcaca tattttaata aaaactgttg atgataaagg
    44581 taagcaagtt agtagtagca aaaaagctga acttaagaaa gaagctgaag aaatacttaa
    44641 aaaagcccaa gctggggaag attttgctac tctagctaaa aaatactctg aagatagtag
    44701 tgcagaatca ggtggagatt taggtttctt tggtaaaggt cagatggtgg aatcttttga
    44761 aaaagcagcc tttgcattga agaagggaga ggtatctaac aaacttgtag aaagtgatta
    44821 tggatatcat ataattaaga aaactgatga aaaatatcag ccatttgaag aggtaaaatc
    44881 agatttagta agcagtttaa catcagaaaa acaaaaccta cttatacaaa atctaaaaga
    44941 aaaatataat gttaaaatta cagataaata tcaaatgaaa gctaaagaat agataaagtc
    45001 aatttattaa aaaaaagaaa aattaactgt atggataaaa gctattttta ctctcaatat
    45061 agagagtata aaatagcttt tatt
//
LOCUS       DAYAOO010000029        42435 bp    DNA     linear   BCT 12-OCT-2024
DEFINITION  TPA_asm: Clostridioides difficile isolate ST8-SSI-h139-18
            SAMN40601845-rid21577343.denovo.029, whole genome shotgun sequence.
ACCESSION   DAYAOO010000029 DAYAOO010000000
VERSION     DAYAOO010000029.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN40601845
            Sequence Read Archive: SRR28438827
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 42435)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 42435)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-MAY-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-MAY-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002157583.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002157583.1
            Genome Coverage       :: 163x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/11/2024 16:19:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 4,038
            CDSs (total)                      :: 3,963
            Genes (coding)                    :: 3,930
            CDSs (with protein)               :: 3,930
            Genes (RNA)                       :: 75
            rRNAs                             :: 6, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 60
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 33
            CDSs (without protein)            :: 33
            Pseudo Genes (ambiguous residues) :: 0 of 33
            Pseudo Genes (frameshifted)       :: 7 of 33
            Pseudo Genes (incomplete)         :: 25 of 33
            Pseudo Genes (internal stop)      :: 11 of 33
            Pseudo Genes (multiple problems)  :: 8 of 33
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..42435
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN40601845-rid21577343.denovo.029"
                     /isolate="ST8-SSI-h139-18"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Denmark"
                     /collection_date="2018"
                     /collected_by="Statens Serum Institute"
     gene            complement(214..420)
                     /locus_tag="ACGI5H_001728"
     CDS             complement(214..420)
                     /locus_tag="ACGI5H_001728"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888870.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9697437.1"
                     /translation="MTKLEDNMERFFGGCEGFFGNKMLIIIVIVFLLLCTDILEDLLC
                     DDNIWIWVILIVLLLFNFDDGCCC"
     gene            complement(468..893)
                     /locus_tag="ACGI5H_001729"
     CDS             complement(468..893)
                     /locus_tag="ACGI5H_001729"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428561.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9697438.1"
                     /translation="MKYVGLLLTSVGMFLLIAVNFYYNSITLDMQRIEDYVMETNLIL
                     EDVAEKESYVSNEKEDYISRLMHVKKGIENSKTSFLIERYKEYKIKSIESLIYTISEE
                     KKDYLDEVDRYNKLGEKEINKLINKNFLEVTYLSITTYI"
     gene            1065..1292
                     /gene="acpP"
                     /locus_tag="ACGI5H_001730"
     CDS             1065..1292
                     /gene="acpP"
                     /locus_tag="ACGI5H_001730"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418905.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000036 - acyl carrier activity [Evidence
                     IEA];
                     GO_process: GO:0006633 - fatty acid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="acyl carrier protein"
                     /protein_id="HFG9697439.1"
                     /translation="MFEKIKEIIAEQLGVDNLDEITMEASLMDDLEADSLDAVEIIMA
                     LEDEFGIEIPDEEAENFKCIGDICKYIEENK"
     gene            complement(1436..2440)
                     /locus_tag="ACGI5H_001731"
     CDS             complement(1436..2440)
                     /locus_tag="ACGI5H_001731"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729497.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoid-associated protein"
                     /protein_id="HFG9697440.1"
                     /translation="MIIHKFIIHVLDKNSDVPILNDFEGKVNQEVDGFFQKAIKRIAK
                     DEDLRKGVFKDYNDNLIKNCCEQIIYDESTFLKNSKEIASYLFDVMKINAALESCDLA
                     ICLYTIKDEKSVAILKLDYKKLYTHSIEFVDDKFNIQMVSNEIGIPETLRQKQGALIS
                     LSGINDEFHLRLLDKDAEKEGSESKFVTEFLNAKKIDDDKYKTKVFKNTAENWITNAL
                     SNDIKQAEDVRSILNYTLKEKHEVDINDFVDNSIKDDELKDSFKEHMEEKGLDESFSI
                     DKKWVEKKLKKRSIKTDNGFDIKGNLTDFEDPMKYTVKQNQDGTIDIIIKNVTFYEEK
                     "
     gene            complement(2454..3356)
                     /locus_tag="ACGI5H_001732"
     CDS             complement(2454..3356)
                     /locus_tag="ACGI5H_001732"
                     /EC_number="5.4.99.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428566.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0009982 - pseudouridine synthase activity
                     [Evidence IEA];
                     GO_process: GO:0001522 - pseudouridine synthesis [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="RluA family pseudouridine synthase"
                     /protein_id="HFG9697441.1"
                     /translation="MFKKENQRYNLISYTNEEEMTLKEVLLDKLNFSVRSLSKMKREK
                     SVLVNGVYKKPSLKVYSGDLIEVKIDEEKANFEPQDLNLQIIYDDFDIIMVNKPPFMV
                     VHPTKSHYDKTIANGISYYIDNQKENVKIRFVNRLDMNTSGLVIVAKNAYAHHTLSTA
                     MSENKVEKKYITVVDGIIKENEGTIDEPIYRPTEDSIKRIIDERGQSSVTHYKVIERL
                     ENATVLEVSLETGRTHQIRVHMAHIGHGIIGDELYGYVDEELINRQALHAYKLEFEQP
                     RTKEKLKFKADIPEDMKELISKLR"
     gene            complement(3551..4726)
                     /locus_tag="ACGI5H_001733"
     CDS             complement(3551..4726)
                     /locus_tag="ACGI5H_001733"
                     /EC_number="2.3.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888868.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016747 - acyltransferase activity,
                     transferring groups other than amino-acyl groups [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA C-acetyltransferase"
                     /protein_id="HFG9697442.1"
                     /translation="MREVVIASAARTAVGSFGGAFKSVSAVELGVTAAKEAIKRANIT
                     PDMIDESLLGGVLTAGLGQNIARQIALGAGIPVEKPAMTINIVCGSGLRSVSMASQLI
                     ALGDADIMLVGGAENMSMSPYLVPSARYGARMGDAAFVDSMIKDGLSDIFNNYHMGIT
                     AENIAEQWNITREEQDELALASQNKAEKAQAEGKFDEEIVPVVIKGRKGDTVVDKDEY
                     IKPGTTMEKLAKLRPAFKKDGTVTAGNASGINDGAAMLVVMAKEKAEELGIEPLATIV
                     SYGTAGVDPKIMGYGPVPATKKALEAANMTIEDIDLVEANEAFAAQSVAVIRDLNIDM
                     NKVNVNGGAIAIGHPIGCSGARILTTLLYEMKRRDAKTGLATLCIGGGMGTTLIVKR"
     gene            complement(4813..5658)
                     /locus_tag="ACGI5H_001734"
     CDS             complement(4813..5658)
                     /locus_tag="ACGI5H_001734"
                     /EC_number="1.1.1.157"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0006631 - fatty acid metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="3-hydroxybutyryl-CoA dehydrogenase"
                     /protein_id="HFG9697443.1"
                     /translation="MKLAVIGSGTMGSGIVQTFASCGHDVCLKSRTQGAIDKCLALLD
                     KNLTKLVTKGKMDEATKAEILSHVSSTTNYEDLKDMDLIIEASVEDMNIKKDVFKLLD
                     ELCKEDTILATNTSSLSITEIASSTKRPDKVIGMHFFNPVPMMKLVEVISGQLTSKVT
                     FDTVFELSKSINKVPVDVSESPGFVVNRILIPMINEAVGIYADGVASKEEIDEAMKLG
                     ANHPMGPLALGDLIGLDVVLAIMNVLYTEFGDTKYRPHPLLAKMVRANQLGRKTKIGF
                     YDYNK"
     gene            complement(5756..6553)
                     /locus_tag="ACGI5H_001735"
     CDS             complement(5756..6553)
                     /locus_tag="ACGI5H_001735"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428571.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003824 - catalytic activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="enoyl-CoA hydratase-related protein"
                     /protein_id="HFG9697444.1"
                     /translation="MSTSDVKVYENVAVEVDGNICTVKMNRPKALNAINSKTLEELYE
                     VFVDINNDETIDVVILTGEGKAFVAGADIAYMKDLDAVAAKDFSILGAKAFGEIENSK
                     KVVIAAVNGFALGGGCELAMACDIRIASAKAKFGQPEVTLGITPGYGGTQRLTRLVGM
                     AKAKELIFTGQVIKADEAEKIGLVNRVVEPDILIEEVEKLAKIIAKNAQLAVRYSKEA
                     IQLGAQTDINTGIDIESNLFGLCFSTKDQKEGMSAFVEKREANFIKG"
     gene            complement(6572..7582)
                     /locus_tag="ACGI5H_001736"
     CDS             complement(6572..7582)
                     /locus_tag="ACGI5H_001736"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418892.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0009055 - electron transfer activity
                     [Evidence IEA];
                     GO_function: GO:0050660 - flavin adenine dinucleotide
                     binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="electron transfer flavoprotein subunit
                     alpha/FixB family protein"
                     /protein_id="HFG9697445.1"
                     /translation="MGNVLVVIEQRENVIQTVSLELLGKATEIAKDYDTKVSALLLGS
                     KVEGLIDTLAHYGADEVIVVDDEALAVYTTEPYTKAAYEAIKAADPIVVLFGATSIGR
                     DLAPRVSARIHTGLTADCTGLAVAEDTKLLLMTRPAFGGNIMATIVCKDFRPQMSTVR
                     PGVMKKNEPDETKEAVINRFKVEFNDADKLVQVVQVIKEAKKQVKIEDAKILVSAGRG
                     MGGKENLDILYELAEIIGGEVSGSRATIDAGWLDKARQVGQTGKTVRPDLYIACGISG
                     AIQHIAGMEDAEFIVAINKNPEAPIFKYADVGIVGDVHKVLPELISQLSVAKEKGEVL
                     AN"
     gene            complement(7601..8383)
                     /locus_tag="ACGI5H_001737"
     CDS             complement(7601..8383)
                     /locus_tag="ACGI5H_001737"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009524639.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="electron transfer flavoprotein subunit beta/FixA
                     family protein"
                     /protein_id="HFG9697446.1"
                     /translation="MNIVVCIKQVPDTTEVKLDPNTGTLIRDGVPSIINPDDKAGLEE
                     AIKLKEEMGAHVTVITMGPPQADMALKEALAMGADRGILLTDRAFAGADTWATSSALA
                     GALKNIDFDIIIAGRQAIDGDTAQVGPQIAEHLNLPSITYAEEIKTEGEYVLVKRQFE
                     DCCHDLKVKMPCLITTLKDMNTPRYMKVGRIYDAFENDVVETWTVKDIEVDPSNLGLK
                     GSPTSVFKSFTKSVKPAGTIYNEDAKTSAGIIIDKLKEKYII"
     gene            complement(8442..9578)
                     /locus_tag="ACGI5H_001738"
     CDS             complement(8442..9578)
                     /locus_tag="ACGI5H_001738"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009272751.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl-CoA dehydrogenase"
                     /protein_id="HFG9697447.1"
                     /translation="MDLNSKKYQMLKELYVSFAENEVKPLATELDEEERFPYETVEKM
                     AKAGMMGIPYPKEYGGEGGDTVGYIMAVEELSRVCGTTGVILSAHTSLGSWPIYQYGN
                     EEQKQKFLRPLASGEKLGAFGLTEPNAGTDASGQQTTAVLDGDEYILNGSKIFITNAI
                     AGDIYVVMAMTDKSKGNKGISAFIVEKGTPGFSFGVKEKKMGIRGSATSELIFEDCRI
                     PKENLLGKEGQGFKIAMSTLDGGRIGIAAQALGLAQGALDETVKYVKERVQFGRPLSK
                     FQNTQFQLADMEVKVQAARHLVYQAAINKDLGKPYGVEAAMAKLFAAETAMEVTTKAV
                     QLHGGYGYTRDYPVERMMRDAKITEIYEGTSEVQRMVISGKLLK"
     gene            complement(10287..10754)
                     /locus_tag="ACGI5H_001739"
     CDS             complement(10287..10754)
                     /locus_tag="ACGI5H_001739"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428574.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YbaK/EbsC family protein"
                     /protein_id="HFG9697448.1"
                     /translation="MSISNVREYFKQFGKEDSILEFEQSSATVELAAEAAGVIPARIA
                     KTLSFKIGDDAILIVTAGDAKIDNKKYKAEFNCKAKMLTPEEVLEFTGHAIGGVCPFG
                     LKNSIKVYLDDSMKRFDTVFPACGSSNSAIELTCEEMEKFSKCEKWVDVCKNW"
     gene            complement(10833..11375)
                     /locus_tag="ACGI5H_001740"
     CDS             complement(10833..11375)
                     /locus_tag="ACGI5H_001740"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888864.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9697449.1"
                     /translation="MKKFIKVSFFILGIFTLFIAINKLVYRDMVSVKDYEINHLEEIV
                     FDFDSRRSRDVGTIVRFKISNNSKYSYKLNSAKMKFENCVENKKGMNKCSAYVNVDLF
                     NEKNSITERTLKYGIKPNNQGYVDFVIPKGLNFDYRYFNESGMSVEYKGEYIVNIPMA
                     KGLYLVVGKNNDTWNANIME"
     gene            complement(11427..12113)
                     /locus_tag="ACGI5H_001741"
     CDS             complement(11427..12113)
                     /locus_tag="ACGI5H_001741"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905296.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-2 transporter permease"
                     /protein_id="HFG9697450.1"
                     /translation="MFNLIRKDLIIGISSDGIRNLKYILLFFVFYFFLNSISYYTVSI
                     VVSYLIFINTFECDYENDSRIFIRSMPVSIEDIVYSKYLLGVGLIISVTIIVSLLSKL
                     TSLVFFRNMVLNDVFFSVNIFLAILTILLPLIFKFGYGKMKVCGFIVSILIYFVYGSL
                     LKMISMIVYQVKHFNYSKVGGVYLSNYVTDIANTKYINLYSMTFLTIIIFIISMYFSI
                     KISKKNKFNY"
     gene            complement(12113..12973)
                     /locus_tag="ACGI5H_001742"
     CDS             complement(12113..12973)
                     /locus_tag="ACGI5H_001742"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418880.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HFG9697451.1"
                     /translation="MFSIRNITKKLGKFKLNNINLELKEGDIVGIIGPNGSGKTTLIK
                     IIMGIIDADEGEIELCNETIENSPISFKNNIGFVYDSLQFYPHLKVKEFRKIVSLFYK
                     NFDRERFDEYLNKFDIEENMHIENLSKGQSEKLMLSSALSHNAKLLILDEPTAGIDPI
                     VRTEIMQYLQDFVKNGSSSVIISTHNTDNLIKIADYLVFINRGNQIFTVKKELIEQEY
                     KIIRANKAELEAIKESIVGVKEYKYYNEALVKVGDSLKVKSLLIEIDKHKVKNPTIEE
                     LMYYYVNEVR"
     gene            13108..13908
                     /locus_tag="ACGI5H_001743"
     CDS             13108..13908
                     /locus_tag="ACGI5H_001743"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418878.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(+)/NADH kinase"
                     /protein_id="HFG9697452.1"
                     /translation="MKRIITINTNQLNKSLETKELLTRKLINAGFEVYSDIYPDTELI
                     ISIGGDGSFLRTVRDFDFPEIPIMGINTGHLGFFPDILPDKIDSFIEAYTKKDYIIQE
                     MSLLNAEVYTTTSGSNMLAVNEVVIRGDKSRTIHLNLSLDNKHIQNFSGDGMIISTST
                     GSTAYNYSAGGSIVDINLELMQITPLHPINTNAYRCFTSSIICSNESVIKIAPEYRFE
                     DSVLIVVDGVEHRFRQIENIKVSISDAKIKLLRMSNYEFWHRVSEKFL"
     gene            13933..14502
                     /gene="yfcE"
                     /locus_tag="ACGI5H_001744"
     CDS             13933..14502
                     /gene="yfcE"
                     /locus_tag="ACGI5H_001744"
                     /EC_number="3.1.4.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428581.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphodiesterase"
                     /protein_id="HFG9697453.1"
                     /translation="MKIGIMSDTHGSLLYFEKALNVLSDCDVLLHGGDVLYHGPRNDI
                     PEGYNPKKFIETLNKLENIVIVKGNCDADVDQMVIEHPIQSPYVMSQFGEIRIILNHG
                     YIESEEEIIDKAKKMGGDILVLGHTHVKKLYMDDNLIVINPGSTSIPKDGSHSVAIID
                     IIKTDDEDELELDINLIDINTGNIININD"
     gene            complement(14837..15889)
                     /locus_tag="ACGI5H_001745"
     CDS             complement(14837..15889)
                     /locus_tag="ACGI5H_001745"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437956.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall-binding protein Cwp18"
                     /protein_id="HFG9697454.1"
                     /translation="MKIKSKKIIAFALSLGIMLPSCVYADTISKNQNAQVDMNNYLQG
                     RKSPKEEKLIGEDRFDTAIKISQSGWNNGSERVFLVNSNSLPDALASTPLASKLDAPI
                     LLTNKNSIPYNVTEEIKRLNPAEVILIGSEGAISSSVKESLEDMEVLVSRIGGADREE
                     TSLLLTRQLDDTGDLGVSKVAVVNGYNGLADATSISSPAASDNTAIIYTGKDSIRSEA
                     KNFITQNSTKTYIVGGEYSISKKLEGQLVNSERLAGTDRKDTNAKVLEKFYGKSSKVN
                     NMYFAKDGSGREADLVDGLAAGVLASKTKSPVVLASGSLSSAQKSFIKKVKADKFVQV
                     GGGKNSKPYAEALALQ"
     gene            complement(16096..17322)
                     /gene="pepT"
                     /locus_tag="ACGI5H_001746"
     CDS             complement(16096..17322)
                     /gene="pepT"
                     /locus_tag="ACGI5H_001746"
                     /EC_number="3.4.11.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888862.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA];
                     GO_function: GO:0045148 - tripeptide aminopeptidase
                     activity [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase T"
                     /protein_id="HFG9697455.1"
                     /translation="MKQKVVERFLKYVSFDTTSNSQCENCPSSEGQRVLAKYIVEELK
                     TMGVDDVSLDENSYIMATLKGNTDGVDTIGFISHLDTIEDVSGKDIKPRIIENYDGKD
                     IVLNEALNVITYVKDSPELEEFKGDDLIVTDGTTLLGSDDKAGIAEIVTAIEYLINHP
                     EIKHGDIKIGFTPDEEIGRGADLFDVEKFGAKYAYTLDGGIVGELECENFNAANATIT
                     IHGRNVHPGSAKNKMVNAIHIAAEISEMFPADERPETTEGYEGFWHLNSIGGNVENVS
                     MAYIIRDHCKEKFENRKSIMIENIEKINKKYDNRVELDLKDSYYNMKEKIEPVMFIVD
                     IAKEAMEELGIKPRLVPVRGGTDGARLSFNGLPCPNIFTGGLNFHGKNECIPVSSMEK
                     ATKLIVRIAEKYAERV"
     gene            complement(17412..18464)
                     /gene="ytvI"
                     /locus_tag="ACGI5H_001747"
     CDS             complement(17412..18464)
                     /gene="ytvI"
                     /locus_tag="ACGI5H_001747"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437952.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0003674 - molecular_function [Evidence
                     IEA];
                     GO_process: GO:0030436 - asexual sporulation [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sporulation integral membrane protein YtvI"
                     /protein_id="HFG9697456.1"
                     /translation="MSILENNFLYKLKNNTIFFCIYTLLFIFIYKAFPYIAPFFLGAI
                     IALMINPISQKLENKFRINKGISTLVLSFLAVAIVSTVTTIIVINSMKELMGFLNNIS
                     ANPEDISNTIMYFLNKINDFMKSFQEIANFDVEQLVNKFSGEVMQITKNLLTSILGLA
                     TSIPYIIIFIITLFIATYFIAKDLDKIENSFYNMFTVDVRKKVKNVKKEAGLSLVGYI
                     RAYTILMAITFFAIWGSFALFGLKYGLIVGFVGALMDLIPFLGIITIYLPVIVYYFLI
                     KNYFIAISMTVIFFVLSLIREILEPKLVSVNVGLNPLATLAAIFIGIQVKGIIGVIFC
                     LGLVCMHDILKKVDIF"
     gene            complement(18613..19866)
                     /locus_tag="ACGI5H_001748"
     CDS             complement(18613..19866)
                     /locus_tag="ACGI5H_001748"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418863.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HlyC/CorC family transporter"
                     /protein_id="HFG9697457.1"
                     /translation="MLESPNNLIQIIFLIVLLIGSAFFSASETALMSLSKIRIRYMQD
                     EGVKGAKLVSSLIENPNKLLSSILVGNNVVNIAATSISTSLFIGLMGEKGVALATAVM
                     TVLVLIFGEITPKTIAANNSEKVSLLVSKPIKAIIFILRPIVWIFNIITNIIFKLFGI
                     TNKGAKSFITEEELKTMVNVSHEEGVLEMEEREIINNVFEFGDMQAKNAMVQRIDMVA
                     IDMEDSYDEIIQVFKTEKLSRMPVYEETIDDIVGILNIKDIIFLSDEEIESFDIKNYM
                     REPFFTYEFKKITQLLEEMKLEKSQMAIVVDEYGGTSGLLTIEDLVEVIVGDIEDEYD
                     EEEDEIQVIKEDEYIVDGSTKIGDVNELIGVNLESEEFDSIGGFIIGHLSRLPEENEV
                     IEVDNIRFCIESIEKNRIKKIRIYT"
     gene            complement(19997..23524)
                     /locus_tag="ACGI5H_001749"
     CDS             complement(19997..23524)
                     /locus_tag="ACGI5H_001749"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729493.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_process: GO:0006302 - double-strand break repair
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HFG9697458.1"
                     /translation="MRPIRLELTGLNSYIDKQVIDFEKLIERGLFGIFGTTGSGKSTI
                     LDAITIAMYGNISRNTKEYINSVCDKAIISYEFEIGSKNTRRRYIVDRTIARSKTGTK
                     TSNARLIEVLNDNTQNVLADKVVEVNEKVAQVVGLTANDFTRSVVLPQDKFNEFLRLS
                     RADRRDMLERIFNLEKYGRSLGEKVKKRKNIQLQNLKDLKSKLSQYDGITEEVYNNIN
                     QELIELKNLEKDKDNALDLAQKSYEESKTVYEEQLKLEKNELRKNELDLKNSEIKEKI
                     ALVENDSNAKKVDPYISSVQNLEKKIDEDSFAVSNLEKKLAILNQELEVTKNRYEKIN
                     KIKNEEVPKLSEEKIRLQQAIKLEEELVLLDRELKELKESGINLNKTKVELEKVKQVS
                     ESRKDAVTKSIKEVEGKIDKVNISAELKQKIFLAYEYEKDYNNVLEEKNQKLNKLEEI
                     LKETENINLKVRYIDKDKNDVNRNLENLSLHLDVLLKKCPGKSADLLLKSEYVTELRN
                     KANNTKENEIKKSSIQDELKIILESKFNTEREVNLLNEKLENNRKNRDDLEKELEELK
                     YLNLASELRRELKENMPCPVCGSKHHENHDITKYDENISFVKEKLEKLEKEKISIRNN
                     IEELNAKVSGYLSIEKMKTKELEDVKGKLGGIPSSQLLKKLDEEQRKLALLKSNIQEW
                     EKEKESTENKVTLAKEEKNKIEKEELKIRESLNNYKKLTRDLNIEIEGLENKCKKLKQ
                     EYLGLKTITKVSNLLSKVKEIRENEKELELLSTGHSNLLKNRDSLDIKIRENESKLHE
                     IEIELIKARELYVEKKLSRDNKYKEVISITKGDLAKNLLHNVEENICKILEQEESSKK
                     KLEEQRLEYEKNIAEKHNIDGRLKTAKEQYKDQKSTLNKLLAENKFESIYAVKRALLD
                     TDAVKKLIEEILEHEEEQKLLSFKIKSSKEKLNGRSIKKEYFEQLKDEIYNLKVEIGN
                     ISKDIGANQNQLITLKDSLDKINDFNKQLKVVEHNVDLLEELDKCVQGNKFVEYVSTN
                     QLKYIALEASKRLDGITKGRYALEIDSTLNFVMRDNFNGGERRSIDTLSGGETFLTSL
                     SLALALSSQIQLKGSAPLEFFFLDEGFGSLDSELLEIVIESLERLHSNNLSVGIISHV
                     EELKNRVPVKLLVSSSEAGIGSKVKIEYS"
     gene            complement(23511..24722)
                     /locus_tag="ACGI5H_001750"
     CDS             complement(23511..24722)
                     /locus_tag="ACGI5H_001750"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exonuclease SbcCD subunit D"
                     /protein_id="HFG9697459.1"
                     /translation="MRFIHTSDWHLGKSLEGHSRIEEQAKFCEEFIKIVESNEIDMVI
                     IAGDVYDTSNPPAQAEKLFYQTVSRLANNGQRCVLIISGNHDNPERLSAITPLAHEQG
                     ILIYGYPLSATIEAKYKGFEITYATQGCTKLNINGENIVVATLPYPSEKRLNEVFSSE
                     DEFEKQKNYSEKVGDIFRSLEENFRSDTINIAVSHIFVIGGESTESERPIQLGGSFLV
                     ERKDLPEKAQYTALGHLHKQQKASERLNAYYSGSPLQYSKDERAYTKGAYIVDIKAGE
                     KPIIEDVYFNNYKPIEVFKCNGIEEALDICEQNQDREIWSYFEINTDEIISQNEIKKM
                     KELLKDIIEIKPIITSCYEQESVDIKEKSMAELFREFYSFSKGVEPKGELMDLFLDII
                     SEEGESADETN"
     gene            complement(24768..28595)
                     /gene="addA"
                     /locus_tag="ACGI5H_001751"
     CDS             complement(24768..28595)
                     /gene="addA"
                     /locus_tag="ACGI5H_001751"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896009.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003678 - DNA helicase activity [Evidence
                     IEA];
                     GO_function: GO:0016818 - hydrolase activity, acting on
                     acid anhydrides, in phosphorus-containing anhydrides
                     [Evidence IEA];
                     GO_process: GO:0000724 - double-strand break repair via
                     homologous recombination [Evidence IEA];
                     GO_process: GO:0006302 - double-strand break repair
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="helicase-exonuclease AddAB subunit AddA"
                     /protein_id="HFG9697460.1"
                     /translation="MSSPKWTKEQLEVIESRECNLLVAAAAGSGKTAVLVERIIQMIT
                     SRENPIDIDKLLVVTFTNAAASEMRERIGDAIGKALDENPENKHLQNQLVLLNKSSIT
                     TIHSFCLDVIKSNFHRINLDPNFRIGDQTECAILKQEAIEEVFEDLYEERDEGFLNLV
                     ESYAERGGDKEVQDIILGIYSFAMASPEPKKWLIDSAERFNIDENFDFSQSIWARAIL
                     DTVKIEINGLCLNMERALKEVESIEELETFAEKLSVEYKKIADISQACNKSWDEAYKK
                     MASMSFENYVKGVKRISKDAPSYIKESKEKAKTIRDKTKKSLESIVSATFNKDNDSIR
                     EEIKYLYNIVKPISSVVLRFEEEYSNKKREKGIIDFNDIEHFALNILTDVDEKGNIVP
                     SDIAVGCRNKFYEIFIDEYQDSNLVQEVLLKAVANTETPNRFMVGDVKQSIYRFRQAK
                     PELFLQKYNNYNDKKGSSHRKIMLYKNFRSREEVVDAVNYIFENIMNENIGEIEYTEK
                     ERLNLGANFNVDTDEKSIIGGATEIHLIQKDNKLDDDIINDKDDRINNKENEIEEEEK
                     LDNIQLEARMVGNIIKDLMKVNEDGKIQKVYDKGIDGYRPVEFRDIVILLRATSAWAP
                     VFADELMNMDIPTYADVGVGYFDTIEIKTILSLLQIIDNPMQDIPLISVLKSPIFGFT
                     PEDLIDIRVQSKDKIFYEVLKSTAEYDGFTDSQNENESEFIPSEECINKSKDFLIKLK
                     EFKEKSMYMSTDEFIWYLYTRTGYYAYVGALPGGSQRQANLKVLFERAKQFEETSLKG
                     IFNFVNFIEKLKKSSSDMGSAKTLGENANVVRIMSIHKSKGLEFPVVICSAMGKNFNT
                     QDFKKSILYHHNLGYGPQFVDYERRISFPSIAKEALKSKINIENLSEEMRVLYVAFTR
                     AKEKLIITGSTRNIQDSIKRWSNGIESLDTISQYEILKGKNFLDWIMPCVLRHRDLSN
                     LLEEVGLDAVFNVEHNSKWYGKLWNKNDILVEKKSDEEKESIEEILEKIDVNNPDSDY
                     YGEIEEKLNYIYPYEFSTRKPATISVTEIKKIQNNYEEELINTIFEQKVILKKPLFIQ
                     NEEEREKISGTERGTIVHLVMEVLDLKNVSSVNDIKSQIRGFVSKGIITEKQASIVNP
                     YKIYKFFASNIGKRMLNAEIINREKSIYAQVNMKDIYIYEKLINNDDKKLYDNESVML
                     RGIVDAYFEEDNQIVLVDYKTDFVNEENINQIIEKYKKQLDLYADIIETLTGKSVKEK
                     CIYLFGVDEAVCY"
     gene            complement(28595..32062)
                     /gene="addB"
                     /locus_tag="ACGI5H_001752"
     CDS             complement(28595..32062)
                     /gene="addB"
                     /locus_tag="ACGI5H_001752"
                     /EC_number="3.1.-.-"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861078.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004527 - exonuclease activity [Evidence
                     IEA];
                     GO_process: GO:0000724 - double-strand break repair via
                     homologous recombination [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="helicase-exonuclease AddAB subunit AddB"
                     /protein_id="HFG9697461.1"
                     /translation="MGLRFVLGRSGSGKSTYILDEIKKEAQKNETTSIILLVPEQYTF
                     EAENRVSKLFLGKEKDKYLRVRVLSFKTLSNIVFSQVGGLTDVNINSSGKAMMVYRAI
                     EDVSEELNVFSKSKSQSGFVSSITDMISEMKQYNISPEMLENISGELDNETLSLKLKD
                     ISKIYNSFEGKLHENYVDAQDMLTSLASKIELSSYLDGACVYIDEFTGFTPNQYNVIK
                     SILNKSKSVNISLTVDDINYIGYSKSDMFSRTKFTYSKLTQLCNEEGIKILPQVNLNT
                     GVIKRFEKVKELQHLERFYNAYPYKIYSNPTENIKIKEFNNLYSEVEEIAREIVHLVR
                     DKNVRYRDITIATRDLNRYDFLVHSIFNEYNIPNFIDKKREAKSNPIVILIISALEMK
                     NRRYGYETMFRYLKSGLIGIDNDDINLLENYVLANGIKGKKWFDEKWDYRITQSLSGQ
                     ESEFELELKEKINEIKNRVLEPIVILQEKLRGKNRVKEICRYIYEFLLDINMPETIES
                     LIVNFKDKGELDVANQYSQVWDIVVDILDQMVELMGDEIISLEKFIKLITLGFDEYEL
                     GLVPPSIDQVLVSSVDRMKNPDTKYLYLVGTTDGVFPLITKDSGILSDNDRESLGNKG
                     IEVDIDSKTRSFEEQFLVYKALTSTSKNLTITYPISDHEGKTLRPSIIISRLKKIFPN
                     IENKSYLVEENKSTDKDILKKITVKSPTFNELINVIKNYDSDGYNTEEINSIWLDIYR
                     YYLKDEIYSSITKKVIKGLSYTNQVHKIEEKKIRSLYKSNSLSISRLEKYAECPFAYF
                     IQYGLKAKKRKEYSFTPPDLGTFIHNILDRFSKELLQDNLTWRDIDEKYIELKIGIIV
                     DEIILKIPGYILNSSERYKYLAYRLKNMLTTAITIISQQIKQGSFEPIDYEVKFGNNG
                     KYPPIKMVLENGQEVSLIGQIDRVDEFEEGENKYIRIIDYKSGNKSISLTEIYYGLQL
                     QLLVYLDAILESAKDEDININPAAILYCRINNPIAKFNEDKDDEEIQEAILKELRMKG
                     LVVKDSHIVKEMDKSLIDGERKNSLVIPVGLTKDGNVGKSTSAISYEDFKLLRKYVRH
                     AIKDLCEEMLSGEIRIAPYKHKDGTSCDFCDYSAICQFDSTIKDNKYKNLNNKSNEEI
                     IKMMKGDVN"
     gene            complement(32052..32882)
                     /locus_tag="ACGI5H_001753"
     CDS             complement(32052..32882)
                     /locus_tag="ACGI5H_001753"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418847.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PD-(D/E)XK nuclease family protein"
                     /protein_id="HFG9697462.1"
                     /translation="MNDKLKYFSYSQNSINTYKSCPLKFKYKYIDRINWKNDDVGSRE
                     YYETLKTGRDFHLICERYFSNIPLGIYFNEDDKNSKKFLKWMENIKKVVPIEKGKTYL
                     PEYEVRMTLNGDIIQAKYDLVVIGNNNIEIWDWKTESKKIDYKHVENRIQTIVYMFLA
                     KEVIPKVLKMDINVKDINMRYYQPEFDDLPITILYDEEKHEANRNKIQNYISMIKNTN
                     YEEHTYEDNLYNDIEKVYNKEERMCYRNKKHCKYCEFNKLCNGKEIDYSILEAEIYGT
                     "
     gene            complement(32991..35210)
                     /locus_tag="ACGI5H_001754"
     CDS             complement(32991..35210)
                     /locus_tag="ACGI5H_001754"
                     /EC_number="3.6.4.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428591.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0004386 - helicase activity [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent helicase"
                     /protein_id="HFG9697463.1"
                     /translation="MININYREDQIPIINYDNGTMAVPAVPGAGKTFIITNLVAKLLL
                     EQKHKGGKILILTYMNSAVNNFKGRIRKILEENKIDDTNSYEVMTIHSLAVKIIKEKP
                     EVVMLSEDFNIADDLQKSIILNECISRFRFEGGERAFRWFLKEQKDERWKEITLEAWE
                     RGFFEFAGNAISELKYKGISPDNLEEILSRGHKGMLKIILPIYKLYDRKLKQNGLLDY
                     DDILILAEKTLSLDEGLRKKFQTRYKYIFEDECQDSNEIQGNIIKIISSENKNLVRVG
                     DINQSITGTFSSSDPKFFKEFINSADFCYRMDMSNRSSKDILDLANTLVKYVTKEFRQ
                     KECRHALEDMQIKTVPNGMGYKENPNPEHYNINVKWYESWKIEIEQTARYVKGIKNKY
                     PDKSIGILVPFNEQVTQVAKELRENNLTFEELGPNSLNKRKVINNIAYIIDFMLHCDD
                     VEKLIVVLNKVFIDTDNEEEIKYFLEELKNYSTEEIIYNFEFSKLDNDLIEFKEESDI
                     YLSFKRGIDIIKQILEYPIIRLDLLVLFIGKKLNLEKEDKAVLDYISFYIKYLVSENI
                     NMDLEDVYNLLFDVKNRVFNHIIDVVYEINGYEPEPGSITLCNYHKSKGMEWDCVFLL
                     GLVEYNFPDNINQKFQSDKWYLKEKYKNPMAIIKSEVEAILKGSISTDYAHKTKIDSI
                     NEKIRLLYVGITRAKEMLVLSGSAYRDESDIGNKRKEQKPCIYLSRLNQHIIEKRSN"
     gene            complement(35203..37116)
                     /locus_tag="ACGI5H_001755"
     CDS             complement(35203..37116)
                     /locus_tag="ACGI5H_001755"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729491.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9697464.1"
                     /translation="MEYLFEKSSLKEYGNEALDKYRELLDKTGNNSRCILLLVPNNNT
                     KIRYERSLRLNYSEELKITTYISFVKKELVKYWPLIIEKCDEISTKVVSPTFISNSLS
                     EYLIVQKVKEKRIQEGYFEDITGTNKSIANSIMTNINKSAFNLIDFDFIGEKIYSSKK
                     NKDSIYRFSYTQMDEIISYYINSLLSNSILDNALSIYLYNQYLLNDDFYLKNLFTEVR
                     YIIVDSLESSSNAEVDFITEALDNTLQSYIYFDYSRDYSVFNNVDIDYINEKIISKIK
                     PKEENIKKKEIRIEDLYLLPANIELNQSSQLYNEMLDLISEKVISLIEEDVSPRDIAI
                     ISPINNSILEHQIRDSLIEKNIDVFSTKKDKKAVDYPYGNALVVATCIFYGYLDFIKD
                     DEYLSFLETLLEINRIKAFKIFNETRHLSIDNIDEHSQYREILQYIEEKKKSDIKIHE
                     FLTQFYIDKMLNLKEGKKNVGLCKKIIAESESFSESLSLLGMKKEKIFIEALKSTIND
                     YYSVVDIEELKSKDKIVITTPYSYISSNIDRSIQIWVDIGSNAWNMKIEKDISNLIVL
                     RKSFEEKKIYTNEMEEYYKKYYLYNTVYNLLLNAKKIYAFKSEYAINGYIQESILYSI
                     LLKISHKGDKNYD"
     gene            complement(37358..39370)
                     /locus_tag="ACGI5H_001756"
     CDS             complement(37358..39370)
                     /locus_tag="ACGI5H_001756"
                     /EC_number="3.5.1.28"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892871.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008745 - N-acetylmuramoyl-L-alanine
                     amidase activity [Evidence IEA];
                     GO_process: GO:0009253 - peptidoglycan catabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase"
                     /protein_id="HFG9697465.1"
                     /translation="MRRNTKLLTTGILSMAIVAPTMAFATESNAMENNADLNINLEKK
                     SIVLGSKSKVSVKFKEKPDADSITLKYKCYDMPLNTTLNYNQSTGAYEGTINYNQDPE
                     YLNVWELQGITINSKNNPKTLNRQDLEKLGLNLKDYNVTQECIIEDITSRKDVNKYLR
                     KTSSPITELTGSDRYETAVKISKEGWKNGSDKVVIINGDVSIDGIISTPLATTYNAPI
                     LLVEKNNVPNSVKSELKRLNPKDIIIIGDENAISKTTANQIKSTVNASQTRLNGSNRY
                     ETSLLIAKEIDKNHDVEKVYITNANGGEVDALTIAAKAGQDKQPIILTDKDSITDNTY
                     KWLKSEDLQNAYFIGGPQMISTNVINKVNGITKDSVTNNRVYGADRHETNANVIKKFY
                     TDDELEAVLVAKSDVLVDALAAGPLAANLKSPILITPKTYVSAYHKDNLEAKSANKVY
                     KIGGGLTSKVMSSIASSLSKHNTTPTEPGNSGGKTVMIDPGHGGSAPGNSSGGMIEKD
                     YNLNTSLATTEYLRSKGFNVIMTRDTDKTLSLGNRTALSNSLKPDLFTSIHYNGSTNK
                     QGHGVEVFYKLKDKNGGTTKTVATNILNRILEKFKLTNRGIKTRVLPSDSTKDYLYVL
                     RSNDMPAVLVECAFLDNENDMSLINSSAKVKEMGTQIGKGIEDSLK"
     gene            complement(39875..41893)
                     /locus_tag="ACGI5H_001757"
     CDS             complement(39875..41893)
                     /locus_tag="ACGI5H_001757"
                     /EC_number="3.5.1.28"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892871.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008745 - N-acetylmuramoyl-L-alanine
                     amidase activity [Evidence IEA];
                     GO_process: GO:0009253 - peptidoglycan catabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase"
                     /protein_id="HFG9697466.1"
                     /translation="MRRNTKLLTTGILSMAIVAPTMAFATESNAMENNADLNINLEKK
                     SIVLGSTSKVSVKFKEKPDADSITLKYKCYDMPLDTTLNYNQSTESYEGTINYNKDPE
                     YLNVWELQGITINSKNNPKTLNKQELEKMGLNLKDYNVTQECIIEDITSRKDVNKYLR
                     KTSAPITELTGSDRYETAVKISKEGWKNGSDKVVIINGDVSIDGIISTPLATTYNAPI
                     LLVEKNNVPNSVKSELKRLNPRDVIIIGDENAISKTTANQIKSTVNASQTRLKGSNRY
                     ETSLLIAKEIDKNHDVEKVYITNANGGEVDALTIAAKAGQDKQPIILTDKNSITDNTY
                     KWLKSEDLQNAYFIGGPQMISTNVINKVNDITKDNVTNNRVYGADRHETNANVIKKFY
                     TDDELEAVLVAKSDVLVDALAAGPLAANLKSPILITPKTYVSAYHKENLEAKSANKVY
                     KIGGGLTSKVMSSIASSLSKHNTTPTEPGNSGGKTVMIDPGHGGSDTGTTGKPLGGIR
                     EKDYTLNTSLATTEYLRSKGFNVIMTRDTDKTLSLGNRTALSNSLRPDLFTSIHYNAS
                     DTTGNGVEVFYKLKDKDGGTTKTVATNILNRILEKFNLKNRGAKTRTLSTDPTKDYLY
                     VLRNNDMPAVLVECAFLDNEKDMSLLNTSNKVKEMGTQIGKGIEDSLK"
     gene            complement(42167..42283)
                     /gene="rrf"
                     /locus_tag="ACGI5H_001758"
     rRNA            complement(42167..42283)
                     /gene="rrf"
                     /locus_tag="ACGI5H_001758"
                     /product="5S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00001"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00001"
     gene            complement(42292..42365)
                     /locus_tag="ACGI5H_001759"
     tRNA            complement(42292..42365)
                     /locus_tag="ACGI5H_001759"
                     /product="tRNA-Gly"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(42331..42333),aa:Gly,seq:tcc)
BASE COUNT        13029 a         7556 c         4340 g        17510 t
ORIGIN      
        1 catccttctt ctccaaagaa tctatctaac attatacgtt acctcctgtt gatattttgt
       61 tgagcttttc gctcctaaca tatactatgc atttggtttc cattttgcta atgtattttt
      121 actatttttt taaatttttt aatttgaact aaaaaaggta aaaccataac ttgtataagt
      181 tactggtttt acctatttaa taatcaatat tttttagcaa caacaaccat catcgaagtt
      241 aaataataac aatactatta atataaccca tatccatata ttgtcatcgc ataataagtc
      301 ttctaaaatg tctgtgcata atagtaagaa tactataact attattatca acattttatt
      361 cccaaaaaat ccttcgcatc ctccaaagaa acgttccata ttgtcttcta attttgtcat
      421 aactaatcct ccttgaatca ttaagagact aagttttgtc tctttaatta aatatatgta
      481 gtaatagaca gataagttac ttctaaaaag tttttattga ttagtttatt tatttctttt
      541 tcaccaagtt tattgtatct atcaacttca tccagataat cttttttctc ctctgatata
      601 gtatagatta aactttctat tgattttatt ttgtactcct tatatctttc tatcaagaag
      661 gatgtttttg aattttctat tcctttcttt acatgcatta accttgatat gtagtcttct
      721 ttttcattag atacataact ctccttttca gctacatctt caaggattaa attggtctcc
      781 attacataat cctctatacg ttgcatatct aaagttattg aattataata aaaatttact
      841 gctataagta aaaacattcc tactgaagtt agtaatagtc ctacatattt catagcattt
      901 cctcctaagt tatatttgtt atcaataaag tttattcatc aaataatact ttattactac
      961 atttataaaa ttttattatt ttttatagat tccatattga aaaattcttg atattatatt
     1021 aaactaacat taaaattaat taaaactgct ttaggaggct taaaatgttt gagaaaataa
     1081 aagaaataat agcagaacaa ttaggggtag acaatttaga tgagataact atggaagcat
     1141 ctttaatgga cgacttagaa gctgattcat tagatgctgt tgaaattata atggcccttg
     1201 aagatgaatt tggaatagaa ataccagacg aggaagctga gaactttaaa tgtattggtg
     1261 atatatgtaa atatatcgaa gaaaacaaat agtatcgttt tgtctacaaa tataaatagt
     1321 ctgtgtaaac ttctacataa taaattatat tagagttcgc acagactaga ttacatttat
     1381 ttacaatata taaaatacac gctcttatat ttaatttata tactaagtat ataaattact
     1441 tttcttcata aaacgtaaca ttctttatta ttatatctat agttccatct tgattttgtt
     1501 ttacagtata cttcattggg tcttcaaaat cagttagatt cccttttatg tcaaaaccat
     1561 tatccgtttt tatacttctt tttttaagct ttttctcaac ccatttttta tctatactaa
     1621 aactttcgtc aagacctttt tcttccatat gctctttaaa gctatccttt aactcatcat
     1681 ctttaattga attatcaaca aagtcattta tatcaacttc atgtttttcc ttcagtgtat
     1741 aatttaatat acttcttaca tcttcagctt gctttatatc attactaaga gcattggtta
     1801 tccaattttc agctgtattt ttaaatacct tggtcttgta cttatcatca tctatttttt
     1861 tagcatttaa aaattctgtt acaaacttag attctgaccc ttctttttca gcatccttat
     1921 ctaaaagcct tagatgaaac tcatcattta taccacttag actaatcaaa gctccttgct
     1981 tttgtcttaa agtctctggg ataccaattt catttgaaac catttgaata ttaaatttat
     2041 catccacaaa ttcaattgaa tgagtgtaca actttttata atctaatttc agtattgcta
     2101 cactcttttc atctttaata gtgtataaac aaattgccaa atcacaagat tctagtgcag
     2161 cattaatttt cataacgtca aacaagtaag atgcaatttc tttagaattt ttcaaaaaag
     2221 tactttcatc atatattatt tgttcacaac agtttttaat taaattgtca ttataatctt
     2281 taaaaacacc ttttcttaaa tcctcatctt ttgcaattct ttttatagct ttctggaaaa
     2341 aaccatccac ttcttgatta actttgcctt caaagtcatt taatattgga acatcactat
     2401 ttttgtccaa aacatgtatt ataaatttat gtattatcat atatatcacc ccattatctt
     2461 aatttcgata ttaactcttt catatcctct ggtatatctg ctttaaattt caatttttct
     2521 tttgttcttg gttgttcaaa ctctagctta tatgcatgaa gtgcttgcct atttattagc
     2581 tcttcatcta cataaccata caactcatca cctattattc catgacctat atgagccata
     2641 tgtactctta tttgatgtgt tctaccagtt tctaagctta cttctaatac agttgcattt
     2701 tctagtcttt ctattacttt atagtgagta acagatgact gtcctctttc atctattatc
     2761 ctctttattg aatcttctgt aggtctataa attggctcat ctatagttcc ctcattttct
     2821 tttataattc catcaactac tgttatatac tttttttcaa ctttattttc actcattgct
     2881 gtagacaaag tatgatgtgc ataagcattt tttgctacta taactaaccc tgaagtattc
     2941 atatctaacc tatttacaaa tcttattttt acgttttctt tttgattatc tatatagtaa
     3001 ctaataccat ttgctattgt tttatcatag tggctttttg ttgggtgaac taccataaac
     3061 ggaggtttat tcaccataat tatatcaaaa tcatcataaa ttatctgtaa atttaaatct
     3121 tgaggttcaa aatttgcttt ttcctcgtct atttttactt ctattaaatc accactatac
     3181 acctttaaac tcggtttttt atatactcca tttactaaaa cactcttttc cctcttcatt
     3241 tttgataatg acctaactga gaaatttagc ttgtccaata aaacttcttt taaagtcatt
     3301 tcttcttcat ttgtatacga tataagatta tatctttgat tctctttttt aaacaaactt
     3361 ttacctactt tcttttatat cttcctactt tttatatctt caaaatcatg atattatata
     3421 ttttacacta tttttgttta atagataata attattttta actataaaaa cctgtaagaa
     3481 taacaaatag ttattcttac aggttaaatt cataattaaa tatttaattt gtaaatatta
     3541 taatctaaaa ctatctctta actattaaag tagttcccat tcctccacct atacaaagtg
     3601 tagcaagacc agttttagca tctcttctct tcatttcata taaaagtgta gtaagtattc
     3661 ttgctcctga gcatcctatt ggatgtccta tagctattgc tccaccatta acattaactt
     3721 tattcatatc tatatttaag tctcttatta cagctacaga ttgggcagca aatgcctcat
     3781 tagcttcaac taaatctata tcttcaatag tcatattagc agcttctaaa gcttttttag
     3841 ttgctggaac tggtccatat cccattattt tagggtcaac accagctgtt ccataagaaa
     3901 ctatagttgc aagaggctct attcctagtt cttcagcttt ttctttagcc attactacta
     3961 gcatagcagc accatcattt attcctgatg cattaccagc agtaactgtt ccatcttttt
     4021 taaatgcagg tcttaactta gcaagtttct ccattgtagt gccaggctta atatattcat
     4081 ctttatctac tacagtgtca ccttttcttc cttttataac aacaggaact atttcttcat
     4141 caaattttcc ttcagcttga gctttttcag ctttattttg acttgcaaga gctaattcat
     4201 cttgttcttc tctagttata ttccattgct ctgctatgtt ttcagcagta atacccatgt
     4261 gatagttatt aaatatgtct gataatccat cttttatcat tgaatcaaca aaagcagcat
     4321 cacccattct tgcaccatat ctcgcacttg gtactaaata aggagacata ctcatgtttt
     4381 cagctccacc aactaacatt atatcagcat cacctaatgc tataagttga gatgccattg
     4441 aaacagatct taatccagaa ccacaaacta tatttatagt catagctggt ttttctactg
     4501 gtattcctgc tcctaatgct atttgtcttg ctatattttg tccaagacct gctgtaagta
     4561 ctccccctaa aagagattca tctatcatat ctggagttat gttagctctt tttatagctt
     4621 ctttagctgc tgttacccct aactctaccg ctgaaactga tttaaatgct cctccaaaac
     4681 ttcctactgc tgttctagct gcactggcaa ttactacttc tctcatattc attaccccca
     4741 ttaaattaga tttttcatat atccgaaatt gttttttaaa caattttatt taaactttta
     4801 attcccaaat tcttatttat tataatcata gaatcctatc ttagtttttc ttcctaattg
     4861 attagctcta accattttag ctaaaagtgg atgaggtcta tatttagtat ctccaaattc
     4921 agtatataaa acgttcatta tagctaaaac aacatctaat ccgattaaat cacctaatgc
     4981 tagtggtccc attggatggt ttgctcctaa tttcatagct tcatctattt cttctttact
     5041 tgcaacacca tctgcatata taccaacagc ttcatttatc ataggtataa gtattctatt
     5101 tactacaaat ccaggagatt cagatacatc tactggtact ttattgatac tcttagataa
     5161 ttcaaatact gtatcaaaag taacttttga tgttaactga ccacttataa cttcaactaa
     5221 tttcatcata ggaactggat taaagaaatg cattcctata actttatctg gtctcttagt
     5281 agaagaagct atttctgtta tagataatga tgaagtattt gttgccaaga tagtatcttc
     5341 tttacataat tcatctagta acttgaaaac atctttcttt atattcatgt cttctacaga
     5401 tgcttctatt attaaatcca tatcttttaa atcttcatag ttagtagttg aactaacatg
     5461 acttaatatt tctgcttttg tagcttcatc catttttccc ttagtaacta acttagttaa
     5521 atttttatct aataaagcta aacatttatc tatagcacct tgagttctac tctttaaaca
     5581 tacatcatgt ccacaacttg caaaagtttg tacaatacca cttcccatag ttccactacc
     5641 tattacagct aatttcatag ttataacctc ctgttatttt agtatttata ttctgttaac
     5701 tagattaaaa tactatttaa tctagttaac agcaaatata tttttaatta gatttttacc
     5761 cttttataaa gttagcttct ctcttttcaa cgaaagctga cattccttct ttttggtctt
     5821 tagttgaaaa acaaagacca aataaattag attctatatc tattccagta tttatatcag
     5881 tttgagcacc aagttgtatt gcttctttag agtatctaac tgcaagctga gcatttttag
     5941 ctattatctt agctaatttc tcaacttctt ctattaaaat gtctggctca acgactctat
     6001 ttactagccc tattttttca gcttcatcag cttttataac ttgacctgta aagattaatt
     6061 cttttgcttt tgccattcca accaatcttg taagtctttg agttcctcca tatcctggag
     6121 ttattccaag agttacttct ggctgaccaa atttagcttt agcagatgca attcttatat
     6181 cacatgccat tgcaagttca catcctccac ctaaagcaaa tccgtttaca gcagctatca
     6241 ctactttttt actattttct atttctccaa aagcttttgc tcctaagata ctaaaatctt
     6301 tagcagctac agcatctaaa tctttcatgt atgcaatatc tgctccagct acaaatgcct
     6361 ttccttcccc tgtcaatatt acaacatcaa tagtttcatc attattaata tctacaaata
     6421 cttcataaag ttcttctaaa gtctttgaat ttattgcatt aagggcttta ggtctattca
     6481 ttttcactgt acatatattt ccatctactt caacagctac attctcataa actttaacat
     6541 cacttgtact cataataccc tccccaagaa attagttagc taaaacttca cctttttctt
     6601 ttgcaacact taactgactg ataagttctg gaagcacttt atgaacatct ccaactatac
     6661 caacatcagc atatttaaat attggagctt ctggattttt atttatagca actataaact
     6721 cagcatcttc cataccagct atatgttgta ttgctccaga tataccacat gctatataaa
     6781 ggtctggtct tacagtttta ccagtttgac caacttgtct tgctttatct aaccaacctg
     6841 catctatagt ggcacgagaa ccagaaactt ctccacctat aatttcagct aattcataaa
     6901 gtatgtctaa gttttctttt ccacccattc cacgtccagc agaaactaat atcttagcat
     6961 cttctatttt aacttgtttt ttagcttctt ttattacttg tacaacttga actaatttat
     7021 cagcatcatt aaattctacc ttgaaacggt taattacagc ttctttagtt tcatcaggtt
     7081 catttttctt cataacccct ggtctaactg tagacatttg aggtctgaaa tctttacaaa
     7141 ctattgttgc cattatattt ccaccaaagg caggtcttgt cattaataat aattttgtat
     7201 cttcagctac tgcaagacct gtacagtcag cagtaagacc tgtatgtatt ctagcagaaa
     7261 ctctaggtgc taaatctcta cctattgaag ttgcaccaaa taatacaact atagggtcag
     7321 ctgcttttat tgcttcataa gctgcttttg tatatggttc agttgtatac actgctaaag
     7381 cttcatcatc tactactatt acctcatctg caccatagtg tgctaatgta tctattaaac
     7441 cttctacctt actacctaaa agtaatgcag aaacttttgt atcataatct tttgctattt
     7501 ctgtagcctt tcctagtaat tctaaagaaa cagtttgaat tacattttct ctttgttcta
     7561 ttactactaa aacgttaccc attctttatc cccccttaaa ttatatgata tacttctctt
     7621 ttaatttatc tatgataatt ccagctgatg ttttcgcatc ttcattgtat attgtaccag
     7681 ctggtttaac tgattttgta aatgatttaa atacactagt tggagaacct ttaagaccta
     7741 aattagaagg gtcaacttct atatctttta cagtccatgt ttctactaca tcattttcga
     7801 aagcatcata tattcttcca actttcatgt atcttggtgt gttcatatct ttaagagttg
     7861 ttataaggca tggcatttta acttttaagt catggcaaca atcttcaaat tgtcttttta
     7921 ctaatacata ttcaccttca gtttttattt cttcagcata tgttattgat ggaagattta
     7981 aatgttcagc tatttgaggt ccaacttgtg cagtatctcc atctatcgcc tgtcttccag
     8041 ctattataat atcaaaatct atatttttta atgctcctgc taatgctgat gaagttgccc
     8101 aagtatcagc acctgcaaat gctctatctg ttaataatat acctctatct gcacccattg
     8161 ctaaagcttc ttttaaagcc atatctgctt gaggaggtcc cattgttata acagttacat
     8221 gagcacccat ttcttctttt aattttatag cttcttctaa acctgcttta tcatcagggt
     8281 ttattatact tggtactcca tctctaatta aagtacctgt attaggatct agtttaactt
     8341 ctgttgtatc tggaacttgt tttatacaaa cgactatatt cataaatcct tcctccatat
     8401 ctattttaat atcgacctat tgtgtatatt ttaatattta tctattttaa taattttcct
     8461 gaaataacca ttctttgaac ttcactagtt ccttcatata tttcagttat cttagcatct
     8521 ctcatcattc tttctactgg atagtcacga gtgtatccat atcctccatg aagttgtaca
     8581 gcttttgtag taacttccat agctgtttca gctgcaaata attttgccat tgctgcttct
     8641 actccataag gttttcctaa gtctttattt atagctgctt gatatacaag gtgtctagcc
     8701 gcttgtacct taacttccat atcagctaat tggaattgtg tattttggaa ttttgataat
     8761 ggtctaccaa attgtactct ttcttttaca tatttaacag tttcatcaag agcaccttgt
     8821 gctaaaccta aagcttgtgc agctatacca attctaccac catcaagagt agacattgct
     8881 atcttaaatc cttgaccttc ttttccaagt aaattttctt taggtattct gcaatcctca
     8941 aatattaatt cactcgtagc tgaacctctt atacccattt tcttttcttt aactccaaag
     9001 ctaaacccag gagttccttt ttcaactata aatgctgata ttcctttgtt ccccttagat
     9061 ttatcagtca ttgccattac tacatatatg tcaccagcta ttgcatttgt tataaatatt
     9121 tttgagccat taagtatgta ttcatccccg tctaaaacag cagttgtttg ttggccagac
     9181 gcatctgtac cagcattagg ctcagtaaga ccaaatgctc ctaatttttc tccacttgct
     9241 aatggtctta agaatttttg tttttgttct tcattaccat attgatatat aggccatgag
     9301 ccaagagatg tatgagctga taatataact cctgtagtac cacaaactct agacaattct
     9361 tcaactgcca ttatatatcc tacagtgtct ccaccttctc caccatattc ttttggatat
     9421 ggtataccca tcattcctgc ttttgccatt ttttccactg tttcataagg aaatctttct
     9481 tcttcatcaa gttctgttgc taaaggttta acttcatttt cagcgaagct tacatatagc
     9541 tctttaagca tctgatattt tttagaattt aaatccataa tagcctcctc agtattttat
     9601 aaatatttta ttttcattta ttaattaaaa tctcggcaac atctataata aggtatttga
     9661 atatacgtcg agaaatttat aaccttaatc aaactacgct ctatatttat atgtgattat
     9721 actaaccaat tatgacatta atttaatcat aaattgttaa tttaaaatca actatactta
     9781 aaaaaaatct cgctttttgg aattttgtga aatttcaagt tagaataaga tttctttcac
     9841 actggttaga gataaaataa tttgtttacg atatttatat taaggtatat taaacattaa
     9901 atattgtctg tacatctgtt ttttagccat gtacagaaga tttttatcgt ataaaaatta
     9961 ttttaataga gctaaataat catattttta tctgactatt ttttattttt aaatatctta
    10021 catctataat agtatcactc aaaggataat ttttcaataa tttctaatta tttttttaac
    10081 aatatttatt acattttttc cacttttttg tcattttttt attgtttcga aaaaaaatca
    10141 gaatttttta actttatttt ggattattag tttaaattag attttcctct tagatttata
    10201 aatatttaca caaaaaaact acctctgtat agattgtata cagaggtagt tttttactaa
    10261 ttcctactat agtttactat atttttttac caattcttac aaacatctac ccatttttca
    10321 cacttagaaa acttctccat ttcttcacat gtaagttcta ttgcagagtt actactgcca
    10381 catgcaggaa atactgtatc aaatcttttc attgaatcat ctaaatagac ttttatagaa
    10441 ttttttaaac caaatggaca gactccacca atagcatgtc cagtaaactc caagacttct
    10501 tctggtgtca acattttagc cttacaatta aattcagcct tatacttctt attatcaatc
    10561 ttagcatcac cagctgtcac aattaaaatt gcatcatctc ctattttaaa tgagagtgtc
    10621 ttagctattc ttgctggaat aaccccagct gcttcagctg caagttccac agtagcacta
    10681 gattgttcaa attctaatat actgtcttcc ttgccaaatt gtttaaaata ctctcttaca
    10741 ttacttattg acattaaata cccctcctag tctgaacttt tataaatttc atattattct
    10801 taattatatc tataattgat ttatttttca aattattcca taatattagc attccatgta
    10861 tcattatttt ttccaactac tagataaagt ccttttgcca ttggaatatt gacaatatat
    10921 tctcctttat actctacact cataccagat tcattaaagt acctataatc aaaatttagt
    10981 ccttttggaa ttacaaaatc aacataacct tgattatttg gttttattcc atatttcaga
    11041 gttctttcag ttatagaatt tttttcatta aataaatcta catttacata tgcagaacac
    11101 ttattcattc cctttttatt ttccacacaa ttttcaaact tcattttagc actgtttaat
    11161 ttataactat atttactatt attgcttatt ttaaatctta caatagtacc aacatctcta
    11221 cttctcctgc tatcaaaatc aaaaacaatt tcctctaaat gatttatttc ataatctttg
    11281 acacttacca tatctctata tactaattta tttatagcta tgaatagtgt aaaaatcccc
    11341 aaaataaaaa atgaaacttt tataaacttc ttcattttta gtctccttat attttgtgct
    11401 attgtgctat aatattaatc aaaattttaa taattaaact tattcttttt tgaaatctta
    11461 atagaaaaat acattgatat tataaaaatt attattgtta aaaatgtcat actatataaa
    11521 tttatatact tagtattagc tatatcagtt acataatttg aaagatatac tcctccaact
    11581 ttactataat taaaatgctt tacttgatat acaatcatac taatcatctt caaaagactt
    11641 ccatatacaa agtaaattaa aatacttact ataaaaccac aaactttcat ttttccatat
    11701 ccaaacttaa aaattaaagg cagtaaaatc gtcaaaattg ctaaaaatat atttacagaa
    11761 aaaaatacat catttaaaac catatttcta aagaacacta gtgatgtcaa tttacttagt
    11821 aaggacacaa ttattgttac agaaattatt aatcctacac ctaataaata ttttgagtaa
    11881 actatatctt ctatactaac tggcatactc cttataaaaa tccttgaatc attttcataa
    11941 tcacactcaa atgtatttat aaatatcaaa taactaacaa caatacttac tgtataatat
    12001 gaaattgaat taaggaaaaa ataaaacaca aaaaatagca atatgtactt taaattacgg
    12061 ataccatctg aactaatccc tattattaaa tcttttctta ttaaattgaa catcatctca
    12121 cctcatttac ataataatac attagttctt ctatagtagg atttttgacc ttatgcttat
    12181 caatttctat caataggctt tttactttca agctatctcc aactttaaca agtgcctcat
    12241 tataatattt atactctttc acaccaacta tgctttcttt aattgcttct aactctgctt
    12301 tatttgccct aattatctta tattcttgtt ctattaattc tttcttaaca gtaaaaatct
    12361 gatttcctct atttataaaa acaagataat cagcaatttt aattaaatta tcagtattat
    12421 gagtagaaat tattacacta ctacttccat ttttcacaaa atcttgtaag tactgcatta
    12481 tttcagttct tacaattggg tctatcccag cagttggttc atccaaaatc aataacttag
    12541 cattgtgact aagtgcactt gataacataa gcttttcaga ttgaccttta gataaatttt
    12601 caatatgcat attttcttct atatcaaact tattaaggta ttcatcaaac ctttctctat
    12661 caaaattctt ataaaataaa gaaactattt ttctaaattc cttaaccttt aaatgcggat
    12721 aaaattgtaa agaatcatat acaaaaccaa tattgttttt aaagcttatt ggagaatttt
    12781 caatagtttc attacaaagt tcaatttcac cttcatctgc atcaataatc cccattataa
    12841 tttttattaa agtcgttttt cccgaaccat ttggtcctat aatcccaaca atatcccctt
    12901 cctttaactc taagtttata ttatttaact tgaattttcc taattttttt gtgatattcc
    12961 ttatgctaaa cacatcttca cctcttatgc atttttttat acccacctat acatatttta
    13021 acacattcac tacaaaggtc atttataaat ttataaatta agaattataa aactatgtta
    13081 taatacaaag tatgaagagg tgaatatatg aaaagaatta taactataaa tacaaaccaa
    13141 ttaaataagt cccttgagac taaagaactc ttaactagaa aacttatcaa tgctggcttt
    13201 gaagtgtatt cagatattta tccagataca gagcttatta tatcaattgg tggtgatggc
    13261 tcttttttaa gaacagttag agatttcgat tttcctgaaa ttcccataat gggaataaat
    13321 acaggtcatc tggggttttt tcctgatatt ttaccagata agattgatag ctttattgaa
    13381 gcttatacaa aaaaagatta tattattcaa gaaatgtcac ttcttaatgc ggaagtatat
    13441 acaactacta gtggttctaa tatgcttgct gtaaatgagg ttgttataag aggagacaag
    13501 tctaggacta tacacctaaa tttaagcctt gataataaac atatacaaaa ttttagtgga
    13561 gatggtatga ttatttctac ttccacaggt tcaacagcct ataactattc tgctggaggt
    13621 agtattgttg atataaatct tgaacttatg cagattacac ctttacatcc gataaatacc
    13681 aatgcatata ggtgctttac atcaagtata atatgttcaa atgaatctgt tataaagatt
    13741 gcaccagaat atagatttga agattctgta ttgattgtcg ttgatggagt tgagcacaga
    13801 tttagacaaa tcgaaaatat aaaagttagt atatctgatg caaaaataaa attacttaga
    13861 atgtcaaact atgagttttg gcatagagta tctgaaaaat ttttatagac tgtacttagg
    13921 aggattttta atatgaaaat aggaataatg agtgatactc atggtagctt actttacttt
    13981 gaaaaagcgt taaatgtatt atctgattgt gatgttttat tacatggtgg agatgtctta
    14041 tatcatggac ctagaaatga tattccagaa ggatataatc ctaaaaaatt tattgagaca
    14101 ttaaataaat tagaaaacat tgtgattgta aaagggaact gtgatgcaga tgttgaccag
    14161 atggttatag aacatcctat tcagagtcct tatgtcatga gccaatttgg tgaaattaga
    14221 attatattga atcatggtta tatagaatca gaagaagaaa ttattgacaa agcaaagaaa
    14281 atgggtggtg acatattagt tttaggacat actcatgtaa aaaagctata catggatgat
    14341 aatttaatag taataaatcc aggaagtact tctatcccaa aagatggaag ccattctgtc
    14401 gcaattatag atatcataaa aactgatgat gaggatgagc ttgaacttga tataaactta
    14461 attgacatca atactggaaa tataataaat atcaatgatt agtaaatttt taataaaaat
    14521 aaaataagct ttaatttatt aaactcataa taaaaacaag taaaccattt tatttctatc
    14581 tcaattagaa gtttaagtac aataccttaa acttctaatt aaatagaatc tggtttactt
    14641 gttttattat atgctatatt gaaatataac ttagtttact tatttcatta tatattatac
    14701 tgaaatataa cttagtttac ttattttatt atatattata ttgaaacata gcttagttta
    14761 cttattttat tatatatatt gaagtgcaac ttggtttact tgctattatt atatattaat
    14821 tttgatttac acaatattac tgtaaggcta atgcttctgc atatggttta ctatttttac
    14881 ctccaccaac ttgtacaaat ttatcagcct ttactttttt tataaaactt ttctgtgcac
    14941 tacttaaact tccacttgca agtactacag gtgactttgt ttttgatgct aatactccag
    15001 cagcaagccc atcaactaaa tcagcttctc taccacttcc atcttttgca aaatacatat
    15061 tattaacctt acttgatttt ccataaaact tttctaaaac tttcgcatta gtatcttttc
    15121 tatctgtccc tgctagtctt tctgagttta ctaactgtcc ttcaagtttt ttacttatac
    15181 tgtactcccc acctactatg tatgtcttag ttgagttttg tgtaataaaa ttctttgcct
    15241 cacttcttat gctatcctta cctgtatata ttatagctgt attatcactt gcagctgggc
    15301 ttgatattga agttgcatct gccagtccat tatacccatt aaccactgcc acttttgaga
    15361 cacctaaatc accagtatca tctagctgtc tagtaagaag taaagatgtt tcttctctat
    15421 ctgctccacc gattctactg actaatactt ccatatcttc aagagattct tttacacttg
    15481 atgaaatagc tccttcactt ccaattaaaa taacttctgc tggattaagc ctttttattt
    15541 cctctgttac attatatggt atactatttt tatttgtaag cagtattggt gcatccaatt
    15601 tacttgccaa aggagttgaa gccaatgcat ctggcaatga atttgagtta actagaaaca
    15661 ccctttctga accattattc caaccacttt gagatatttt tatcgctgta tcaaatctat
    15721 cttcaccaat aagtttttcc tcctttggag attttctacc ttgaagataa ttgttcatat
    15781 ctacctgtgc attttgattt ttactaatag tgtctgcata tacacaactt ggcaacataa
    15841 tcccaagtga aagtgcaaat gctattattt ttttagattt aattttcaat acaattcccc
    15901 cttttaaatg ttaataccta ttgatattca tactttttat tgatacccta aactaaaaat
    15961 aattatcttt tataaaaata attacaaaaa tagctatacc attttaagta caacacaagc
    16021 ttataatcag cttgacttat aaagaatgat atagctatta taactttaaa tgcttaattt
    16081 ttaaatactt tttaactaaa ctctttcagc atatttttca gctattctta caattagttt
    16141 agtagctttc tccatagaac taactggtat acactcattt ttcccatgga agtttaatcc
    16201 accagtaaat atatttggac aaggtaatcc attaaaagat aatcttgctc catcagtacc
    16261 acctcttaca ggaactaaac gtggttttat acctaattcc tccatagctt ctttagctat
    16321 atcaactata aacataactg gctcaatctt ttctttcata ttgtaataag agtcttttaa
    16381 atccaattcc actctattat cgtatttctt atttattttt tctatattct ctatcataat
    16441 agattttcta ttttcaaatt tttctttaca atggtctcta ataatataag ccatacttac
    16501 attctcgaca tttccaccta tagaatttaa atgccaaaat ccttcatatc cttctgttgt
    16561 ttctggtctt tcatctgctg ggaacatttc tgatatttca gcagctatat gtatagcatt
    16621 taccatttta tttttagctg aacctggatg aacatttcta ccatgtatag taatggttgc
    16681 atttgcagca ttaaaatttt cacattcaag ttctccaact attcctccat ctaaagtata
    16741 tgcatatttt gctccaaatt tttcaacatc aaataaatca gcacctctac caatttcttc
    16801 atctggtgta aatcctattt ttatatctcc atgcttaatt tctggatgat ttattagata
    16861 ctctattgca gtcactatct cagctatacc agctttatca tcagacccaa gtagagttgt
    16921 tccatcagtg actattaaat cgtcaccttt aaattcttcc aactctggag aatcctttac
    16981 atacgtaata acatttaacg cttcatttaa aactatgtct tttccatcat aattttctat
    17041 tattcttggt ttaatatctt ttccactaac atcttcaatt gtatctaaat gtgatatgaa
    17101 tcctatagta tccacaccat cagtatttcc ttttaaagta gccattatat aactattttc
    17161 atctaaactc acatcatcaa cacccattgt ttttagctct tcaactatat acttagctaa
    17221 aactctttga ccttctgaag atggacagtt ctcacactga gaattagatg ttgtatcaaa
    17281 tgatacatat tttaaaaatc tttccactac tttttgtttc acgtatatac cctctttctt
    17341 aataagatta atattttttt atttacctgt gaataaaatt ttatttttaa aaaatctatc
    17401 aattattata attaaaaaat atccaccttc ttaagtatat catgcataca taccaaaccc
    17461 aaacaaaaaa ttactccaat tattcctttt acttggattc caataaaaat cgctgctagg
    17521 gtagctaatg gatttagtcc aacatttact gatactagtt taggttcaag tatttctcta
    17581 atcaaagaca aaacaaaaaa tatcacagtc atacttatag ctataaaata attttttata
    17641 aggaaataat aaacaattac tggaagatat attgttatta tacctaggaa tggaattaaa
    17701 tccattaaag ctcctacaaa ccctactatt agaccgtatt tcaatccaaa taaagcaaaa
    17761 cttccccaga ttgcaaaaaa tgttatagcc ataagtattg tataggccct tatatatcca
    17821 acaagtgaaa gccctgcctc tttctttacg ttttttacct tctttctaac atcaacagta
    17881 aacatattat aaaaactatt ttcaatctta tcaaggtctt ttgctataaa gtacgtagca
    17941 ataaacaagg taattataaa tattataata tatggaatag aagtagccaa tccaagtata
    18001 ctagtaagaa gattttttgt aatttgcatt acttcaccac tgaatttgtt tactaattgt
    18061 tctacatcaa aattggctat ttcttgaaat gatttcataa agtcatttat tttatttaaa
    18121 aaatacataa tagtattact tatatcctca ggattagcag atatattatt taaaaatccc
    18181 attaattctt tcattgaatt tattactatt attgtagtaa ctgtactgac tatagccact
    18241 gcaagaaaac ttagaacaag agtagagata cctttattta tacgaaactt attttctaac
    18301 ttttgtgata taggattaat cataagtgct attatagcac ctagaaaaaa tggagctatg
    18361 tatggaaacg ctttgtaaat aaaaataaat aacaatgtat atatacaaaa aaagatagtg
    18421 ttgtttttta atttgtataa aaaattattt tctagtatgc tcatcttaaa aatctccttt
    18481 cttctaattt atatttttat tttgtccatt tcatactagt tttatttgaa tacaaaataa
    18541 aaagaagtgt ataaatataa aagatatctt ttatatttat acacttctaa taaatttaag
    18601 aacattatta cattatgtat atattcttat ttttttaatt ctattttttt ctatactttc
    18661 tatacaaaat cttatattat caacctcaat tacttcattt tcttctggca atctgcttag
    18721 gtgtccaatt ataaaacctc ctatggaatc aaactcctca gattccaagt ttacaccaat
    18781 aagttcatta acatcaccaa ttttagtact tccatctaca atatactcat cttcttttat
    18841 aacttgtatt tcatcctctt cttcatcata ttcatcctct atatctccaa caatgacttc
    18901 tactaaatct tctatagtta aaagtccaga tgttccacca tactcatcta caactatagc
    18961 catctgactt ttttcaagtt tcatctcttc aagaagttgt gttatctttt tgaactcata
    19021 cgtgaaaaaa ggttctctca tataattttt aatatcaaat gactctattt cttcatcaga
    19081 taaaaatata atatctttta tattaagtat tcctacaata tcatctatag tttcttcata
    19141 cacaggcatt ctgcttaatt tttcagtttt aaatacctgt attatctcat cataactatc
    19201 ttccatatct atagctacca tatctattct ttgtaccatt gcatttttag cttgcatatc
    19261 tccaaattca aaaacattat ttatgatttc tctctcttcc atttcaagga cgccttcttc
    19321 atgacttaca tttaccatag tttttagctc ttcttcagtt atgaatgatt tagctccttt
    19381 atttgttata ccaaataatt taaatataat atttgtaatt atattaaata tccatactat
    19441 tggtcttaat ataaatataa ttgcttttat aggtttagat actaatagag aaaccttttc
    19501 tgaattattt gctgctattg tttttggagt aatctcacca aatattaata ctaatactgt
    19561 cataacagct gtagcaagtg ccactccttt ttctcccatt aatcctataa acaaagatgt
    19621 tgatatggat gttgctgcta tatttacgac gttatttcca accaatatag aacttaaaag
    19681 cttatttgga ttttctatta atgaacttac taacttagct cctttaactc cttcatcttg
    19741 catatatctg attctgattt tactcaacga cattaaagcc gtttcagatg ctgagaaaaa
    19801 tgcagaccct ataagtaata ctattaaaaa aataatctga atcaaattat tgggcgattc
    19861 caacacttac cacactccta cttacatgtt tttatattaa tattaattat aaataacttt
    19921 aatattagtt tttattatat cacaattaca tattatttgg aaatattaga taatatattc
    19981 aattaacata tattttctaa ctatattcaa tttttacttt tgaacctatt ccagcctcac
    20041 tagatgaaac taatagctta acaggaactc tatttttaag ttcctcgaca tgacttatta
    20101 tacccacact tagattatta ctatgcaatc tttccaatga ttctataaca atttctaaaa
    20161 gttcactatc taatgaacca aaaccttcat ctaaaaagaa aaattctaat ggtgcacttc
    20221 cctttaattg tatttgagat gaaagagcaa gtgctaatga tagagatgtc aagaatgtct
    20281 ctccaccaga tagagtatca atgcttcttc tttctcctcc attaaagtta tctctcatta
    20341 caaagtttag tgttgagtca atttcaagtg catatcttcc ttttgttatt ccatccaatc
    20401 gttttgatgc ttccaacgct atatatttta attggtttgt agaaacatat tctacaaatt
    20461 tatttccttg tacacattta tctaattctt ccaataagtc cacattgtgt tcaactacct
    20521 taagttgttt attaaaatca tttatcttat ctaaagagtc ttttaatgtt attaactgat
    20581 tttgattagc tccaatatct ttggatatat ttcctatttc tactttcaaa ttataaattt
    20641 catcttttaa ctgttcaaag tactccttct ttatgcttct tccatttaat ttttcttttg
    20701 atgattttat tttaaatgat aataactttt gttcttcttc atgctctagt atttcttcaa
    20761 tcaatttttt tactgcatca gtatctaata aagctctttt tactgcatat atactttcaa
    20821 atttattttc tgctaatagt ttatttagtg ttgatttttg gtctttatat tgttccttag
    20881 cagttttaag tctaccatct atattgtgct tttcagcaat gtttttttca tattctaatc
    20941 tttgctcttc caattttttc ttacttgatt cttcttgttc taatatctta catatatttt
    21001 cttcaacatt atgtaaaaga tttttagcta aatcaccttt cgttatgcta ataacttctt
    21061 tatacttatt atctctactc aatttctttt ctacatataa ttctctagcc tttattaatt
    21121 ctatctctat ttcatgtagt ttactctcat tttctcttat tttaatatct agtgagtctc
    21181 tattttttaa taaatttgaa tgcccagtac ttagtaattc taattctttt tcattctctc
    21241 ttatttcttt tacttttgac aatagattag agactttagt aatcgtcttt aatcctaggt
    21301 attcctgttt aagtttttta catttatttt ctaaaccttc tatttctatg tttaaatctc
    21361 ttgttaattt cttataatta ttcagactct ctcttatttt taattcttct ttttcaattt
    21421 tatttttttc ttctttagct aatgttactt tattttcagt actctctttt tctttctccc
    21481 actcctgaat attagatttt aacaatgcaa gttttctttg ttcttcatca agttttttta
    21541 ataattgact agatggaatc ccccctagtt ttccttttac atcttcaagt tctttagtct
    21601 tcattttttc tatagataaa tacccactta ctttagcatt taattcctct atattgtttc
    21661 ttatacttat tttttctttt tctaatttct ccagtttttc tttgacaaaa gatatatttt
    21721 catcatactt agttatatca tgattttcat gatgttttga cccacaaact ggacaaggca
    21781 tattttcttt taattcacgt ctaagttcag aggctaaatt taaatacttt agttcttcta
    21841 attctttttc taagtcatct ctgttctttc tattattttc aagtttttca tttagtaaat
    21901 ttacttccct ttcagtatta aacttacttt caagtattat ctttaattca tcttgtatac
    21961 tgcttttctt aatttcattt tctttagtat tatttgcttt atttcttaat tcagtaacat
    22021 attcagattt taaaagtaaa tcagcactct taccaggaca ttttttaaga agaacatcca
    22081 agtgaagtga taaattttct aaattacgat ttacatcatt cttatcttta tcaatatatc
    22141 taacttttaa atttatattt tctgtctctt tgagtatttc ttctagttta tttagctttt
    22201 gatttttttc ttccaatacg ttgttgtaat ctttctcgta ttcatatgct agaaatattt
    22261 tttgttttaa ttctgcactt atatttactt tatcaatctt tccttcaact tcttttatag
    22321 atttagtaac tgcatctttt ctggactctg acacctgctt tactttttct aattcaactt
    22381 tagtcttatt taaattaatt ccactttctt ttagctcttt taactctcta tctaataaaa
    22441 ctaactcttc ttctaatttt attgcttgtt gcaatcttat tttttcttca ctcaatttag
    22501 ggacttcttc attcttaatt ttgtttattt tttcatatct attttttgta acttcaagct
    22561 cctgatttaa tattgctaat ttcttttcta aattacttac tgcgaagcta tcttcatcta
    22621 tctttttttc tagattttga actgaactta tgtatgggtc taccttttta gcgttactat
    22681 cattttctac aagagcaatc ttttctttta tctcactatt ttttaaatca agctcatttt
    22741 ttctaagttc atttttttct aactttaatt gttcttcata tactgtttta ctttcttcat
    22801 aagatttttg agctaggtct aaagcattat ccttatcttt ttccaaattt tttaactcta
    22861 ttaattcttg gtttatattg ttgtatactt cctctgtaat tccatcatat tgacttaatt
    22921 ttgatttcaa atcttttaaa ttttgtaact gtatattttt tctctttttc actttttctc
    22981 caagacttct tccatatttc tcaagattaa aaattctctc taacatgtct cttctatctg
    23041 cacgtgataa tcttagaaac tcattaaatt tgtcttgtgg taaaactact gacctagtaa
    23101 aatcatttgc tgttaatcct acaacctgtg ctactttttc atttacttcc acaactttat
    23161 cagctaaaac attttgggta ttgtcattca atacttctat taatctagca ttagaggtct
    23221 ttgttcctgt tttgcttcta gcaatggttc tatctacaat gtatcttctt ctagtgtttt
    23281 tgcttcctat ctcaaactcg tatgatataa ttgccttatc gcacacactg tttatatatt
    23341 cttttgtatt tctggatata tttccataca tagcaatagt tattgcatct aagattgtag
    23401 attttccact tccagtagtt ccaaatatcc caaacaaacc tctttcaatt aatttttcaa
    23461 agtctataac ttgtttatca atatagctat taagccctgt aagttctaat ctaattggtc
    23521 tcatctgctg attcaccttc ttcacttatt atatctagaa ataaatccat aagttctcct
    23581 tttggctcta cacctttact aaaagaatag aactctctaa acaactctgc catagacttt
    23641 tcttttatat ctacactttc ttgttcataa caagatgtta ttattggttt tatttctatt
    23701 atgtctttta atagttcctt cattttttta atttcattct gtgatattat ctcatcagta
    23761 tttatttcaa aatatgacca aatctctcta tcttgatttt gctcacatat atctagtgct
    23821 tcttctattc cattacattt aaatacttct ataggtttgt aattattaaa atatacatct
    23881 tcaattattg gtttttcacc agcttttata tccactatgt atgccccttt ggtatacgct
    23941 ctctcatcct tgctatattg aagtggagaa ccagaatagt atgcatttaa acgttcggaa
    24001 gctttttgtt gtttatgtaa atgacctagt gcagtatatt gagccttttc tggcaaatct
    24061 tttctttcaa ctaaaaaact tccacctaac tgtataggtc tttctgattc agtactctct
    24121 ccacctatta caaatatatg tgatacggct atatttatag tatcacttct aaaattttct
    24181 tctaaacttc taaatatatc tcctaccttt tcagaataat ttttttgttt ctcaaactca
    24241 tcttcacttg aaaaaacttc atttaatctt ttttcacttg gataaggtaa tgtagcaacc
    24301 acaatatttt ctccatttat attcagtttt gtacatccct gagttgcata tgttatttca
    24361 aaccctttat acttagcttc tatcgtagca cttaatggat aaccatatat aagtatcccc
    24421 tgttcatgtg ctagaggtgt tattgcagag agtctctctg gattatcatg atttcctgaa
    24481 attattaata cacacctctg accattattg gcaagtcttg atacagtctg ataaaatagt
    24541 ttttctgctt gtgctggggg attagaagta tcatatacat ctccagcaat tataaccata
    24601 tctatttcat ttgattctac tatttttata aattcctcac aaaactttgc ttgttcctca
    24661 attctagaat ggccttctag ggacttccct agatgccaat ctgatgtatg aataaatctc
    24721 attttttccc cttcctctat cttttaggtt taatttatat ataaaaacta ataacaaaca
    24781 gcttcatcaa ctccaaataa atatatacat ttctctttta ctgacttacc agttaaagtt
    24841 tcaataatat ctgcatataa atccaactgt tttttatatt tctctattat ttgatttata
    24901 ttttcctcat ttacaaaatc tgttttataa tccaccaaaa ctatttgatt atcttcttca
    24961 aaataagcat caactatacc tcttaacatg acactttcat tatcataaag ttttttatcg
    25021 tcattgttta taagcttttc ataaatatat atgtctttca tatttacttg tgcataaatt
    25081 gatttttctc tatttataat ttcagcattc aacattcttt ttcctatgtt agaggcaaaa
    25141 aatttatata ttttatatgg atttactata ctagcttgtt tttctgttat tatacctttt
    25201 gaaacaaaac ctcttatttg tgattttata tcatttacac tacttacatt ttttaagtct
    25261 aaaacctcca taactaaatg gactattgta cctctttctg ttccacttat tttttctctt
    25321 tcttcttcat tttgaataaa tagaggcttt tttaatatta ctttttgttc aaatatagta
    25381 tttattaact cttcttcata attattttgt atctttttta tttctgtaac agatatagta
    25441 gcaggttttc ttgtactaaa ttcatatgga tatatatagt ttaatttttc ttctatttca
    25501 ccgtaataat cactgtcagg attatttaca tctatttttt caagaatttc ttcaatactt
    25561 tctttttctt catcactctt cttttccact aaaatatcat tcttattcca caactttcca
    25621 taccattttg aattatgttc aacattaaaa actgcgtcta atcctacttc ttctagtaga
    25681 ttagataaat ccctatgtct taatacacaa ggcattatcc aatctaaaaa atttttacct
    25741 tttaatatct cgtattgtga tattgtatct aaactttcaa ttccatttga ccatctcttt
    25801 atactatctt gtatatttct agtagaacca gttataatca atttttcttt agctcttgta
    25861 aatgcaacat ataaaactct catctcttct gataaatttt ctatatttat tttgcttttt
    25921 aatgcttctt tggctatact tggaaaagaa atccttctct catagtctac aaattgaggt
    25981 ccatacccta aattatgatg atataaaata ctctttttaa aatcttgagt attgaaattt
    26041 ttacccattg cagagcatat gactactgga aattctagac ctttactttt atgaatactc
    26101 attattctaa caacatttgc attctcacca agtgtttttg cacttcccat atcagaacta
    26161 gattttttta atttctctat aaaatttaca aagttgaata ttcctttaag actggtttct
    26221 tcaaattgtt ttgctctctc aaacaatact tttaaattag cttgtctttg acttccacct
    26281 ggcaatgctc caacataggc atagtatcca gtccttgtgt acaagtacca tataaattca
    26341 tctgtactca tgtacattga cttttcttta aattccttta gcttaattaa aaaatcttta
    26401 cttttgttta tgcactcttc acttggtata aactcagact cattttcatt ttgagaatct
    26461 gtaaatccat catactctgc tgtacttttt aaaacctcat aaaaaatttt atctttactc
    26521 tgaactctaa tatcaatcaa atcctctggt gtaaatccaa atataggtga ttttaataca
    26581 gatataagag gtatatcttg cattggatta tctattattt gaagtaatga caatattgtt
    26641 tttatttcaa tcgtatcaaa ataccccact ccaacatcag catacgttgg tatatccata
    26701 ttcatcaatt catctgcaaa cactggagcc catgcagatg tagctcttaa aagaataact
    26761 atatctctaa attccacagg tctatatcca tctattccct tatcatagac cttttgaatt
    26821 tttccatctt cattgacttt cattaaatct ttgataatgt ttccaaccat tctagcctca
    26881 agttgtatat tatctaattt ttcttcttcc tctatttcat tttctttgtt attaattcta
    26941 tcgtctttat catttataat atcatcatca agtttattat ctttttgtat taggtgtatc
    27001 tccgttgctc caccaataat agatttctcg tctgtatcca cattaaaatt tgcacctaaa
    27061 tttagtcttt ctttttctgt atattcaatt tctcctatat tctcattcat tatattttca
    27121 aatatataat ttacagcatc tacaacttct tctctacttc taaagttttt gtaaagcatt
    27181 atttttctat gggagcttcc ctttttatca ttatagttat tatatttttg caaaaataat
    27241 tctggctttg cttgtctaaa tctatatata ctctgtttta catcaccaac cataaatcta
    27301 tttggagttt ctgtatttgc aacagcttta agcagtactt cctgcactag attactatcc
    27361 tgatattcat ctataaatat ttcataaaac ttgtttctac atccaactgc tatatcagaa
    27421 ggtacaatat tacctttttc atctacatct gtaagtatat ttaatgcaaa atgctctata
    27481 tcgttaaaat ctattattcc tttttctctt ttcttattgc tatattcctc ttcaaatctc
    27541 agtacaacac tagatattgg tttaactatg ttataaagat attttatttc ttctctaata
    27601 gaatcattat ctttattgaa tgtagcactt actatacttt ctaaagactt cttagtctta
    27661 tctcttatag tttttgcctt ttcttttgat tcttttatat acgaaggagc atcttttgaa
    27721 attcttttta ctccttttac ataattttca aaggacatac ttgccatctt tttatatgcc
    27781 tcatcccaag atttattaca tgcttgtgaa atgtcagcaa tttttttata ttcaacggat
    27841 aacttttctg caaaagtttc taattcttct attgattcca cttcttttaa tgccctttcc
    27901 atatttagac aaagaccatt aatctctatt tttacagtgt ctaatatagc tctagcccaa
    27961 atagactgtg aaaaatcaaa attttcatca atattaaatc gttctgctga gtcaatcaac
    28021 cattttttag gttcaggaga agccattgca aatgaatata ttcccaagat aatatcttgt
    28081 acttctttat ctcctcctct ttctgcataa ctttcaacta aatttaaaaa cccctcatct
    28141 ctttcttcat ataaatcttc aaatacttcc tctattgctt cttgtttcaa aatagcacat
    28201 tcagtttggt ctcctattct gaaattaggg tctaagttta ttctatgaaa gtttgatttt
    28261 ataacatcca aacagaatga gtgtattgtt gtaatactag atttatttaa taaaacaagt
    28321 tggttttgta aatgtttatt ttctgggttt tcatctaagg cttttcctat agcatcccct
    28381 atcctctctc tcatttctga cgcagcagca ttagtaaatg taacaactaa taacttatct
    28441 atatcaattg gattttctct acttgttatc atttgaatta tacgctcaac tagaacggct
    28501 gtttttcctg aaccagcagc agcagcaacc aataaattgc attctctact ttctataact
    28561 tctaattgct cttttgtcca tttaggagaa ctcactaatt aacatctcct ttcatcattt
    28621 ttattatctc ttcattactc ttattattta aatttttata cttgttatct tttatagttg
    28681 aatcaaactg acatatagca gagtaatcac aaaagtcaca tgatgttcca tctttatgtt
    28741 tatatggagc tatacgtatt tctccactta acatttcttc acataaatcc tttatagcat
    28801 gccttacata ttttctaagc agtttgaaat cctcatagct tattgctgaa gtacttttac
    28861 ctacatttcc atccttagta agacctactg gtattactaa agagtttttc ctttctccat
    28921 ctattaatga tttatccatc tctttaacta tgtgagagtc ttttactaca agccccttca
    28981 ttctaagttc ttttaatatt gcttcttgta tttcttcatc atctttatct tcattaaatt
    29041 ttgctattgg attatttatt ctacaatata gtattgcagc tggatttata tttatatctt
    29101 catcctttgc actttcaagg attgcatcta aatacacaag taattgtaat tgtagaccat
    29161 aatatatttc tgttagactt atggacttat tgcctgactt ataatctatt attcttatat
    29221 atttattttc tccttcttca aattcatcaa ctctatctat ttgtccaatt aaacttactt
    29281 cttgtccatt ttctaacacc atttttatag gtggatattt tccattgttg ccaaatttaa
    29341 cttcataatc tattggttca aatgaacctt gttttatttg ctgactaatt atagttatag
    29401 cagttgtcaa catattcttt aatctatatg caaggtattt atacctctca gaactattta
    29461 atatatatcc tggtatcttt aaaattattt catcaactat tatacctatc tttaattcta
    29521 tatatttttc atcaatatct ctccaagtta aattatcttg taaaagttct tttgaaaacc
    29581 tatctaaaat attatgaata aaagttccta aatctggtgg tgtaaatgaa tactctttac
    29641 gcttttttgc ttttagacca tattgtataa agtaagcaaa tggacattca gcatattttt
    29701 caagcctaga tatgctaaga gaattacttt tatacaatga ccttattttt ttctcttcaa
    29761 tcttatgaac ttgattagta taactaagac cttttataac tttttttgtt atagaactat
    29821 agatttcatc ttttaaatag tacctatata tatctaacca aatactatta atctcttctg
    29881 tattgtaacc atcactgtca taatttttta ttacgtttat aagttcatta aatgtagggg
    29941 atttaaccgt tattttttta agtatatctt tatcagtgct tttattttct tccactaaat
    30001 aacttttatt ttctatattt ggaaatatct tcttaagtct tgatataatt attgatggtc
    30061 taagcgtttt accttcatgg tctgatattg gatatgttat ggttaaattc ttagatgtcg
    30121 aagtaagagc tttatataca agaaactgtt cttcaaaact cctagtctta ctatcaatat
    30181 caacttcgat tcctttgttt ccaagacttt ccctatcatt atcactcaat attccactat
    30241 cctttgtaat cagcggaaac acaccatcag tagttccaac taggtataaa tatttcgtgt
    30301 ctggattttt cattctatcc acactactta caagtacctg gtctatacta ggaggaacca
    30361 gtcctaattc atattcatca aaacctaagg ttattaattt tataaatttt tctaaagaaa
    30421 ttatttcatc acccataagt tccaccattt ggtctaatat gtccactact atgtcccaaa
    30481 cttgtgagta ttgatttgca acatcaagtt cccctttatc cttaaaattt actattaaac
    30541 tttctatagt ttctggcata tttatatcta ataaaaattc atatatatat ctacagattt
    30601 cttttactct attttttcct cttaattttt cttgtaaaat tactataggc tctaatactc
    30661 tattttttat ttcatttatt ttctctttta attccagttc aaattcactt tcttgacctg
    30721 aaagactttg ggttattcta taatcccatt tttcatcaaa ccatttttta cctttaatcc
    30781 cattagccaa cacataattt tctagtaaat ttatatcatc attatcaatt cctataagtc
    30841 cactttttaa atacctaaac atagtttcat acccatatcg tctattcttc atttctaaag
    30901 ctgaaataat taaaataact attggattac tttttgcctc tctcttctta tctataaagt
    30961 ttggtatatt atattcatta aatatagagt gtactaaaaa atcatatcta tttaaatctc
    31021 ttgtagcaat ggttatatct ctatatctga cattcttatc tctaactaaa tgtacaattt
    31081 ctctggctat ctcttccacc tctgaatata aattgttaaa ctcttttatc tttatatttt
    31141 cagttggatt tgaatatatt ttatatggat aagcattata aaatctttct aagtgctgta
    31201 attccttaac tttttcaaat ctttttataa cacctgtgtt taaatttact tgtggcaata
    31261 tttttatgcc ttcttcgttg cacaattgag tcaattttga ataagtaaat ttcgttctag
    31321 aaaacatatc agatttactg tacccaatat agttgatatc atctacagtc aaagagatat
    31381 taacactttt agacttattt aatatactct ttatgacatt gtactgattt ggtgtaaaac
    31441 ctgtaaattc atctatataa acacaagctc catctaaata actgcttaat tcaattttac
    31501 ttgccaatga agttaacata tcttgagcat ctacataatt ttcatgcaat ttcccttcaa
    31561 aagaattata tattttactt atatctttta attttaaact taaagtttca ttatccaatt
    31621 ctccagatat attttctaac atttcagggc ttatattgta ttgtttcatt tctgatatca
    31681 tatctgtaat tgaacttaca aaaccagact gcgattttga ttttgaaaac acatttaatt
    31741 cttcacttac atcttcaata gctctatata ccatcattgc ttttccacta gaatttatat
    31801 ttacatctgt caatcctcct acttgagaaa aaactatatt acttagtgtc ttaaagctaa
    31861 gtaccctaac tcttagatac ttatcttttt cttttcctaa aaatagttta cttactctat
    31921 tttcagcctc aaatgtgtac tgttctggaa ctaaaagtat aattgatgtc gtttcatttt
    31981 tttgagcttc ttttttaatt tcatctagta tataggtgga ttttccactt ccacttctac
    32041 ctaatacaaa cctaagtccc ataaatttcc gcctccaaaa tactataatc tatttctttg
    32101 ccattacata acttattaaa ttcacaatac ttgcaatgct ttttatttct atagcacata
    32161 cgttcttctt tattatatac cttttctata tcattgtata gattgtcttc gtatgtatgt
    32221 tcttcataat tagtgttttt tatcatactt atataatttt gaattttatt tctatttgct
    32281 tcatgttttt cttcatcata taaaatggta attggtaagt catcaaattc aggttgataa
    32341 tatctcatat ttatatcttt aacatttatg tccattttta aaactttagg tattacttct
    32401 tttgctaaaa acatataaac aatagtttgt attctatttt ctacgtgttt atagtcaatc
    32461 tttttagact cggttttcca atcccatatt tctatattgt tatttccaat tacaactaaa
    32521 tcatactttg cctgtattat atccccattt aatgtcatcc ttacttcata ttctggcaaa
    32581 tacgtttttc ctttttcaat aggaacaact ttttttatat tttccatcca ctttaaaaac
    32641 tttttactat ttttatcatc ctcattaaaa tagattccaa gaggtatatt gctaaaatat
    32701 ctttcacaaa tcaaatgaaa atctcttcct gtttttaaag tttcataata ctctctacta
    32761 ccaacatcat catttttcca atttattcta tcaatatatt tatatttaaa tttcaatgga
    32821 catgatttat atgtgttaat tgaattttga ctataagaaa aatattttaa tttatcgttc
    32881 actcatatca cttctctctt aactttattt tttagtagtt acttactgta catattgttt
    32941 tatccccttt tagatatatt tcaagcaatc ttttaataac ttattatata ttaatttgac
    33001 cttttttcaa taatatgttg attaagtctg cttaaatata tacatggttt ttgctctttt
    33061 ctcttattcc ctatatcact ttcatctcta taagcacttc ctgaaagtac taacatttcc
    33121 tttgctctag taatccctac atataaaagt ctaatctttt catttataga atcaatcttc
    33181 gttttatgag cataatctgt tgaaatactt ccttttaata tagcttcaac ttctgattta
    33241 ataattgcca tagggttttt atatttttct tttagatacc atttatcact ctgaaacttt
    33301 tgattaatat tgtcagggaa attatattca acaagaccta gtaaaaacac acaatcccat
    33361 tccatcccct ttgatttatg atagttacat agtgttatac taccgggctc tggttcatat
    33421 ccatttatct catataccac atctattata tgattaaaca ccctgttctt tacatcaaac
    33481 aataaattat atacatcttc taaatccata tttatatttt ctgatactag atactttata
    33541 taaaaagata tataatccag tacagcttta tcttcttttt ctaaattaag ttttttccca
    33601 ataaacaaaa ctaagaggtc taaccttatt attggatatt ctaatatctg ttttataata
    33661 tctattcctc ttttaaaact taaatatatg tcactttctt ctttaaattc tattaaatca
    33721 ttatctaact tactaaattc aaaattataa ataatttctt cagtagaata gttttttaat
    33781 tcttctaaaa aatactttat ttcttcttca ttatcagtat ctataaaaac tttattaagt
    33841 acaactatta acttttctac atcatcacaa tgtaacataa aatcaataat atatgctatg
    33901 ttgtttataa ccttcctttt attcaaagaa tttggtccta attcttcaaa agttagatta
    33961 ttctctctaa gttctttagc aacttgtgtc acttgttcat taaatggaac caatatacct
    34021 atacttttat ctggatattt attttttata cctttaacat atctagcagt ttgctctatt
    34081 tcaattttcc aactctcata ccactttaca tttatattat aatgttctgg attaggattt
    34141 tctttatatc ccattccatt tggcacagtt tttatttgca tatcttcaag agcatgtcta
    34201 cattctttct gtctaaattc ctttgtaaca tacttgacaa gagtgtttgc taaatcaagt
    34261 atatcttttg aacttcgatt tgacatatcc atcctataac agaaatctgc actatttata
    34321 aattctttaa aaaatttagg gtctgatgat gaaaatgttc ctgttatact ctgatttata
    34381 tctccaactc taactaggtt tttattttcg ctagatataa tttttattat attaccttga
    34441 atttcatttg agtcctgaca ctcatcttca aatatatatt tgtatctagt ttgaaacttc
    34501 tttctaagcc cttcgtctaa gcttaaagtt ttttctgcta aaattaatat atcatcataa
    34561 tctagcaatc cattttgctt taattttcta tcatacaatt tatatattgg taaaataatt
    34621 ttaagcattc ctttgtgtcc tcttgacaat atttcttcaa ggttatctgg agaaattccc
    34681 ttatacttaa gttcacttat tgcatttcct gcaaattcaa aaaaacctct ttcccaggct
    34741 tcaagagtta tttctttcca gcgttcatct ttttgctcct ttaaaaacca tctaaaagct
    34801 ctttctccac cttcaaatct aaatctactt atacattcat ttaatataat acttttttgc
    34861 aaatcgtcag ctatgttaaa atcctcactt aacattacaa cttctggctt ttcctttatt
    34921 atttttacag ccaaactgtg tatagtcatt acttcatacg aattagtatc atctatttta
    34981 ttctcttcaa gaatttttct tattctacct ttaaaattat ttacagcact attcatatat
    35041 gtaagaatta atattttacc acccttatgt ttctgctcaa gtaatagttt agctactaaa
    35101 tttgttatta taaatgtttt tccagcacct ggtactgctg gtactgccat agtaccatta
    35161 tcgtaattta ttattggtat ctggtcttct ctataattta tattaatcat aatttttatc
    35221 tcctttatgt gagattttta aaagtatact atataatata ctctcttgga tataaccatt
    35281 aatcgcatat tcacttttaa atgcatagat tttctttgca tttaataaca aattatatac
    35341 tgtattgtat agatagtatt ttttataata ttcttccatt tcatttgtat aaatcttttt
    35401 ttcttcaaaa gattttctaa gtacaattaa attacttata tctttttcta ttttcatatt
    35461 ccaagcatta cttcctatat ctacccatat ttgtatactt ctatctatat ttgatgatat
    35521 atatgaataa ggagtagtta ttactatttt gtctttggat ttcaactctt ctatatcgac
    35581 aacagagtaa taatcgttta ttgtactttt taaagcttct ataaatatct tttctttttt
    35641 catcccaagt agacttaaac tttcactaaa agactcactt tcagctatta tctttttaca
    35701 taacccaaca ttctttttac cttcttttaa atttaacatt ttatctatgt aaaattgagt
    35761 taaaaattca tgtattttta tatcactctt ctttttttct tcaatatact gtaaaatctc
    35821 acgatactga ctatgttcat ctatattatc aatacttaaa tgtcttgttt cattaaaaat
    35881 cttaaatgct tttatcctat ttatttctaa aagagtttct aaaaagctta agtattcatc
    35941 atcttttata aaatctaaat atccataaaa tatacatgta gccactacca atgcattccc
    36001 atatggataa tccacagctt ttttatcctt cttagtacta aaaacatcta tatttttttc
    36061 tatcaaagaa tctctaattt gatgctccaa tatactattg tttataggag atataattgc
    36121 tatatctctt ggagatacat cttcttctat aagagatata actttttcac ttattaaatc
    36181 taacatttca ttatataatt gacttgattg atttaattct atatttgcag gtaataagta
    36241 taaatcttct attctaatct ccttcttttt aatattttct tctttaggct taatttttga
    36301 tattattttc tcatttatat agtctatatc cacattatta aatacagaat aatccctact
    36361 ataatcaaaa tatatataac tttgtaatgt attatccaat gcttctgtta taaaatcaac
    36421 ttctgcatta cttgagcttt caaggctatc cacaattata tatctcactt ctgtaaataa
    36481 gttttttaaa taaaaatcat cattaagtag gtattgattg tataaatata tgcttaatgc
    36541 attatctaaa attgaatttg atagtaagga atttatataa tatgatataa tttcatccat
    36601 ttgagtgtat gaaaatctat atatactatc tttatttttc tttgatgaat atattttttc
    36661 tccaataaaa tcaaaatcaa ttaaattaaa tgcagactta tttatgttag tcattatact
    36721 atttgctatg gatttattgg ttcctgtaat atcttcaaaa tatccttctt gtatcctttt
    36781 ttccttaact ttttgcacta ttaaatattc acttaaacta tttgatataa atgttggaga
    36841 tacaaccttt gtacttattt catcacattt ttctattatt agtggccagt atttaactaa
    36901 ttctttcttc acaaaactta tatatgttgt tattttcagt tcttcactat aatttaatct
    36961 tagagacctt tcatatcgta tctttgtgtt attgtttggt actaacaaaa gaatacacct
    37021 tgaattatta ccagttttat ctaataattc tctatattta tctaaagctt catttccata
    37081 ttcttttaaa ctactttttt caaataaata ttccatataa tcaccttcct caattaaatt
    37141 aagtgtatat tatctaatta tatcatattg tgtattttac aaaacacatt caaattattg
    37201 catttaacta caaaaaaaga ctgtatatat acttgcattc acacgtgcaa atgtacatac
    37261 agtcttacta ttgatacact tatatttcat tttttgactt tagtataaat ttacaactat
    37321 aaatttacat taagttttta aatattttta tttccattta ttttaatgaa tcttctattc
    37381 ctttacctat ttgtgtaccc atttctttta cttttgcaga tgagtttatt aaactcatat
    37441 cattttcatt atccaaaaat gcacattcta caagtacagc tggcatatca ttacttctta
    37501 aaacgtataa ataatctttt gtagaatcac taggaagtac tcttgttttt atacctctat
    37561 ttgtaagttt aaatttctct aaaattctat ttaatatatt ggtagctaca gttttagtag
    37621 tccctccatt tttatcttta agcttataaa atacttctac accatgacct tgtttattag
    37681 ttgagccatt ataatgtata cttgtaaata aatctggttt caatgaatta gatagagcag
    37741 ttctatttcc aagagataaa gtcttatctg tgtctcttgt cattattaca ttgaatccct
    37801 ttgaacgtaa atattcagtt gttgcaagtg aagtatttaa attgtaatct ttttcaatca
    37861 ttcctccaga tgaatttcca ggtgctgaac caccatgccc tgggtcaatc ataactgtct
    37921 tgcccccact atttcctggt tctgttggag tcgtattgtg tttagataat gatgatgcta
    37981 tagagctcat taccttagaa gtcaatcctc ctcctatttt gtatacctta ttagctgatt
    38041 tagcttctaa attatcttta tggtatgcag atacatacgt ctttggtgtt ataagtattg
    38101 gagactttag gttcgcagcc aatggacctg ctgctaaagc atcaacaagt acatctgatt
    38161 tagctactaa aacagcctct aactcatcat ctgtatagaa tttttttatt acgtttgcat
    38221 ttgtttcgtg tctatctgct ccgtatactc tattattagt aacactatct ttagttattc
    38281 catttacctt atttataaca tttgttgata tcatttgagg accacctata aaataagcat
    38341 tttgtaaatc ctcactcttt aaccatttat atgtattgtc tgtaatacta tctttatcag
    38401 ttaatataat tggttgcttg tcttgacctg cttttgctgc tatagtaagt gcatccactt
    38461 ctccgccatt agcatttgtt atgtatactt tttccacatc atgattttta tctatttcct
    38521 ttgctatcaa taaagatgtc tcatatctat tagaaccatt taaacgtgtt tgactagcat
    38581 ttacagttga tttaatttga ttagcagtag ttttagaaat agcattctca tctccaatta
    38641 taattatatc tttagggttt aggcgcttta attctgattt tacactatta ggtacattgt
    38701 ttttttcaac caaaagtatt ggtgcattat atgtggttgc cagtggagtt gatataatgc
    38761 catctatact tacatcccca tttattataa ctaccttatc tgaaccattt ttccagccct
    38821 ctttacttat tttaactgct gtttcatatc tatcacttcc tgtaagttct gtaataggtg
    38881 aagaagtttt tctcaaatat ttatttacat cttttctaga agttatatct tcaattatac
    38941 attcctgtgt tacattatag tcttttaaat ttaatcccag cttttctagg tcttgtctgt
    39001 ttaaagtttt aggattattt ttgctgttta ttgttatccc ttgtagttcc caaacattta
    39061 gatattctgg gtcttggtta taattgatag ttccttcata tgccccagtt gattgattgt
    39121 aatttagagt tgtattcaat ggcatgtcat agcatttata ctttaatgta atgctatctg
    39181 catctggttt ttctttaaat ttgacactaa cttttgattt gctacctaaa acgatacttt
    39241 ttttctctaa gtttatattt aaatcagcgt tattttccat agcattagat tcagtagcaa
    39301 atgccattgt aggtgcgacg attgccattg aaagaatccc tgttgttaat aattttgtat
    39361 ttcttctcat attaatctcc ttacttaaca taaatttcta ctttattttt aatcttttaa
    39421 cttttgaaaa tatgtcaaag tgtatctaac ccaaaatata aataatatat aagtaatata
    39481 taaaaataaa cttataaaac tcaaaaaata aaaaaattaa atatatttaa tacatttaat
    39541 tatctatact atatcattta ttgacataaa aatccacaaa aaacacacaa acacacaata
    39601 aaatatagta attaagcttt tattgtgtat tacaaatgaa tactccaact cttgacaatt
    39661 aactgtagcc ttaagatatg taaattcttc atataatata aatcctttta caattaatca
    39721 taaaaagact gtatatacct catttcgcac ttatatgcac aatgtatata cagtctttat
    39781 tactattata attacattct tatcttatag ctttagttta aatttaaaat tgcagattaa
    39841 tttattttaa atttttctat gctctcattg tagactattt taatgaatct tctatgcctt
    39901 tacctatttg tgtacccatt tcttttactt tatttgatgt attaagtaaa ctcatatctt
    39961 tctcattatc caaaaatgca cattctacaa gtacagctgg catatcatta tttcttaaaa
    40021 catataaata atcttttgta gggtcagttg atagtgttct tgtttttgca cctctatttt
    40081 ttagattaaa tttctctaag attctattta atatatttgt agctacagtt ttagtagtcc
    40141 ctccatcttt atctttaagc ttataaaata cttctacacc attcccagtt gtatcagatg
    40201 cattatagtg tatactcgta aataaatctg gtctcaaaga gttagataaa gcagttctat
    40261 ttccaagaga taaagtctta tctgtgtctc ttgtcattat tacattgaat ccctttgaac
    40321 gtaaatattc agttgtcgca agtgaagtat ttaatgtata gtctttttct ctaatacccc
    40381 ctaatggttt acctgttgtt ccagtgtccg aaccaccatg tcctgggtca atcataactg
    40441 tcttgccccc actatttcct ggttctgttg gagttgtatt gtgtttagat aatgatgatg
    40501 ctatagagct cattacctta gaagtcaatc ctccacctat tttatatacc ttatttgccg
    40561 atttagcttc taagttttct ttatggtatg cagatacata tgtctttggt gttataagta
    40621 ttggagattt taagttcgca gccaatggac ctgctgctaa agcatcaaca agtacatctg
    40681 atttagctac taaaacagcc tctaactcat catctgtata gaattttttt attacgtttg
    40741 catttgtttc gtgtctatct gctccatata ctctattatt agtaacatta tctttagtta
    40801 tatcatttac cttatttata acatttgttg atatcatttg agggccacct ataaaataag
    40861 cattttgtaa atcctcactc tttaaccatt tatatgtgtt gtctgtaata ctatttttat
    40921 cagttaatat aattggttgc ttgtcttgac ctgcttttgc tgctatagta agtgcatcca
    40981 cttctccgcc attagcattt gttatgtata ctttttccac atcatgattt ttatctattt
    41041 cctttgctat caataaagat gtctcatatc tattagagcc ctttagacgt gtttgactag
    41101 catttacagt cgatttaatt tgattagcag tagttttaga aatagcattc tcatctccaa
    41161 ttataattac atctctagga tttaaacgct ttaattctga ttttacacta ttaggtacat
    41221 tgtttttttc aaccaaaagt attggcgcat tatatgtagt tgctagtgga gttgatataa
    41281 tgccatctat acttacatcc ccatttatta taactacctt atctgaacca tttttccagc
    41341 cttctttact tattttaact gctgtttcgt atctatcact tcctgtaagt tctgtaatag
    41401 gtgcagaagt ttttcttaaa tatttattta catcttttct agaagttata tcttcaatta
    41461 tacattcctg cgttacatta tagtctttta aatttaatcc catcttttct agttcttgtt
    41521 tgtttaaagt tttaggatta tttttgctgt ttattgttat cccttgtagt tcccaaacat
    41581 ttagatattc tgggtcttta ttataattga tagttccttc atatgactca gttgattgat
    41641 tatagtttaa agttgtatcc aatggcatat catagcattt atactttaat gtaatgctat
    41701 ctgcatctgg tttttcttta aacttaacac tgacttttga ggtactacct aaaacgatac
    41761 tttttttctc taagtttata tttaaatcag cgttattttc catagcatta gattcagtag
    41821 caaatgccat tgtaggtgcg acgattgcca ttgaaagaat ccctgttgtt aataattttg
    41881 tatttcttct catattaatc tccttattta acataaattt ctactttgtt ttttaacctt
    41941 ttaatttttg aaattatatc aaagtgtttt tacccaaaat tataaataag tacataaaaa
    42001 ataaacttct aaaaaaatta taaaaacaaa aaataaaaaa attaaatata ttgaatatat
    42061 ttaattatct tcactatatc atttattgcc aaaaaaatct ataaaagaca aataaaaaca
    42121 tataacaatt gtaggtttat taaatttaat acaacaaaaa aagattacgt ggctacgtcc
    42181 tactctccca ggcagtttcc caccaagtac catcagcgct agagagctta acttctgtgt
    42241 tcggaatggg aacaggtgta tcctctctgc tattgtaacc acataatctt ttggagcggg
    42301 tgaaggggat cgaaccctca cagctggctt ggaaggccag aactctacca ttgagctaca
    42361 cccgcattaa atttttataa attagtaaaa ctaatttttt agagttagca ctctaaaaac
    42421 tacatatata tccta
//
LOCUS       DAYAOO010000030        41783 bp    DNA     linear   BCT 12-OCT-2024
DEFINITION  TPA_asm: Clostridioides difficile isolate ST8-SSI-h139-18
            SAMN40601845-rid21577343.denovo.030, whole genome shotgun sequence.
ACCESSION   DAYAOO010000030 DAYAOO010000000
VERSION     DAYAOO010000030.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN40601845
            Sequence Read Archive: SRR28438827
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 41783)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 41783)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-MAY-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-MAY-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002157583.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002157583.1
            Genome Coverage       :: 163x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/11/2024 16:19:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 4,038
            CDSs (total)                      :: 3,963
            Genes (coding)                    :: 3,930
            CDSs (with protein)               :: 3,930
            Genes (RNA)                       :: 75
            rRNAs                             :: 6, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 60
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 33
            CDSs (without protein)            :: 33
            Pseudo Genes (ambiguous residues) :: 0 of 33
            Pseudo Genes (frameshifted)       :: 7 of 33
            Pseudo Genes (incomplete)         :: 25 of 33
            Pseudo Genes (internal stop)      :: 11 of 33
            Pseudo Genes (multiple problems)  :: 8 of 33
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..41783
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN40601845-rid21577343.denovo.030"
                     /isolate="ST8-SSI-h139-18"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Denmark"
                     /collection_date="2018"
                     /collected_by="Statens Serum Institute"
     gene            complement(202..1311)
                     /locus_tag="ACGI5H_001760"
     CDS             complement(202..1311)
                     /locus_tag="ACGI5H_001760"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454747.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HFG9697467.1"
                     /translation="MSEVILKNISKLYSNGFNAVKNINIDIKDKEFIVLVGPSGCGKS
                     TTLRMIAGLEEISEGELYIGDKLVNNIEPKDRDIAMVFQNYALYPHLSVYENMAFALK
                     LRNLPKDEIDKKVKEAAKILDLLPLLNKKPKTLSGGQRQRVALGRAIVRNPKVFLMDE
                     PLSNLDAKLRTAMRTEITKLHQQLGTTFIYVTHDQVEAMTMADRIVVMKDGVVQQIAT
                     PQDVYDYPANIFVAGFIGAPQMNFIDVILIEENDEIYAQNEHIKLKLNKEKHYDLIKD
                     NYINNEVVIGIRPEDIHVEDTFIKSNPDTCFKSRIEIKELMGAETYAHLKLGENTITI
                     RFDSKNRINVGDDLTLSVDNSRVHIFDKETTLAIR"
     gene            1569..2306
                     /gene="cas6"
                     /locus_tag="ACGI5H_001761"
     CDS             1569..2306
                     /gene="cas6"
                     /locus_tag="ACGI5H_001761"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416586.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004521 - RNA endonuclease activity
                     [Evidence IEA];
                     GO_process: GO:0043571 - maintenance of CRISPR repeat
                     elements [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="CRISPR-associated endoribonuclease Cas6"
                     /protein_id="HFG9697468.1"
                     /translation="MSRISIFMESCNGKFPNENSMLSVSFIKNILNAENKDFAKNIFN
                     YGEERKNNKQIKDINTAIYIPNLIRSKNELLVDGDIIFNISFYNYSMFSKLYNGILKV
                     KELEYKGYRFKIKNIKIHKEHEIKENGVIFKTMSPIIVKNKEGKYLDVEDSNYIECLN
                     YIANLTLESIRGSGLRKPLEFIPINFKKRVLKEKIRGFKVREYYYINAYAGTFFLKGD
                     MEDLNALYKMGIGYRRTENAGMVDILK"
     gene            2311..3786
                     /locus_tag="ACGI5H_001762"
     CDS             2311..3786
                     /locus_tag="ACGI5H_001762"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890662.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9697469.1"
                     /translation="MREIKAKFYRSGDIVRDIGIVYFYELLMDLKNELEKNDYKLKFT
                     CELNRNYLSLESAEYIDPKYISDYILENRLFKVFKNGKKETLEKIFSNIDNLTYVNFI
                     EELDKSSATAKQKEDIKKDFKNRRFPYVRNSGKYGLNTSLENMETNVKRIVDTVIKSN
                     IEIDEIDKLDLTQYEEKDSVCNVCNINKTTKLDIDLRERKDSKYNFLFRGAEKSGFKR
                     SGQVESNICFECEFFNLMCLLYINLKRPMVFAYTNDLRELAFLNHKIMLKRKMYSDKS
                     FYKKLLHEKISSIRLYSFDIDTNKGIILKFDSIIEYKELLKKIELIDIIDNYNFSREP
                     GNTRNLGKRMIDNGNLSNLKELLLDNISVLKQSTGTSREMDFVSSSYNIGLYIKLCWI
                     VDGGEEYKMKNYMESNLIYSRVGKDLFNKMTDESRRKNFSMKVIQLLKSNDRTQLFQT
                     IMHVLVSNGILIGEGFVEGLMQSSELELNTNVGLFIQEIMK"
     gene            3806..4819
                     /locus_tag="ACGI5H_001763"
     CDS             3806..4819
                     /locus_tag="ACGI5H_001763"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416591.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003674 - molecular_function [Evidence
                     IEA];
                     GO_process: GO:0043571 - maintenance of CRISPR repeat
                     elements [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DevR family CRISPR-associated autoregulator"
                     /protein_id="HFG9697470.1"
                     /translation="MNEKRVKGVTLTILTESPVPLSYDQGYGNYTPIKKEQYREKIHA
                     KTSIATITYDLRRMLHQEYGWNLSNIVFGKKGNIYPSIKKNVGCVDENGLETDVFGYL
                     IPLKDKGSISKASPLRIIPFRSLNPYKGSTQLITNRGFLSSEFGRKYYDEKEENEVPR
                     DENFPTSQALAIEETLSDYYVYTITLELDRIGVVEVEDGKLLLPEERKFMSKELREKA
                     VKDILDAITVFTRNIKHSSVLLKPLAVIGGAFDKVVPFFWDDVDYNADSGEINLEGVI
                     ETIESYSLKESNTILAINDRLKISNKKELNKFNLSKYPVKEIKNLADRLEIGEDNMWY
                     LKE"
     gene            4835..5632
                     /gene="cas5"
                     /locus_tag="ACGI5H_001764"
     CDS             4835..5632
                     /gene="cas5"
                     /locus_tag="ACGI5H_001764"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430916.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003674 - molecular_function [Evidence
                     IEA];
                     GO_process: GO:0043571 - maintenance of CRISPR repeat
                     elements [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="CRISPR-associated protein Cas5"
                     /protein_id="HFG9697471.1"
                     /translation="MKVLQCKLKQPTAHYRDPKVFQNEYISTLNLPSKTTIMGMITYL
                     CDRRLNSDIDIGIIGTHHHRELEFSRGENIDFWNEYIKMGKGKDKEKFLLKGNYYDYY
                     KEHKAQNSILNYEVLKEVELTIFISCKDDEELEFIRKKLESPCKYANLGRKEDFVIPS
                     EKGCFVKEVKLKEVIPMNTRDAIKENIKLKNTYVRVDLRDKENVETIINQGVLIALPH
                     KYKDLEANRDDRVYEFCHYIYVDNDGIYPKNIKVNVCIDTKEVFTWL"
     gene            5659..8067
                     /locus_tag="ACGI5H_001765"
     CDS             5659..8067
                     /locus_tag="ACGI5H_001765"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454738.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CRISPR-associated helicase/endonuclease Cas3"
                     /protein_id="HFG9697472.1"
                     /translation="MKNIMQKEILAKSYNLRTNQQEQTLVEHIKDLFEVLESILELNL
                     YSDKDVEILKICCALHDLGKINSIMQQKMEINNKISYSCSEEERKKLESDKKSLKKIA
                     RHNIFSGAFLKDILEKMNLSEEDKLYIYKSIMLHHGNYEDYMRLSISKVQEEIYEYIE
                     KGILEKEEFNLKDIESYINSILNVDFKFGEDVLDYDYIDKLSESMFIDSDYNNGQIDD
                     SVLNYRKFKYILYKGMLNLIDHSASSRQKGIKFYNDFTDEEIDNMILNEIYKSQGNLE
                     KNNIEFNTIQKRLRELSGRNVLTVAFTGSGKTAADYRKTFKRKFFLVPNKISAESFYR
                     KNIFQNKNDLDTRSSNDYIGLLHGDINLYSENEDNGEHDFVLTLRDIDLSINFCKPCV
                     IATVDQLLLSMFKFPGYEKIFAAVKNASITVDEVHLLEPKMFLILIYFMQFACKYLDV
                     DFHLMTATLPKSYKEQMINKGIIFQEESNENVTDKGEIVFIESNKEEEICEGKDVKVS
                     FIKEKEIKSIVEDALENKQKILIIKNTIDSVNRTYEFLKENLSDKYGGVDIDVLHSRF
                     KFKDKKEKYSKILNGEGDIWISTQSVEISLDLDFNIIISDLATMDSLIQRMGRCNRNN
                     KYEYGNFYILPSEDKIYDNKLKSTTKNILKDILKTNSIFTMGIRKTILDDYYDNSVVK
                     KYFEENFISCDKEIKNIYGVNKEIFDGLDLIFNFEPYKNIVDSKKEAAKIFRDVDVSY
                     KIILEEDFYKEDRELQQDSIQVSGFIFNRLYYYGLISKVEGYMVLKSSSKFEYNSTVG
                     LILK"
     gene            8508..9455
                     /gene="prmA"
                     /locus_tag="ACGI5H_001766"
     CDS             8508..9455
                     /gene="prmA"
                     /locus_tag="ACGI5H_001766"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454737.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008757 - S-adenosylmethionine-dependent
                     methyltransferase activity [Evidence IEA];
                     GO_process: GO:0036211 - protein modification process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L11 methyltransferase"
                     /protein_id="HFG9697473.1"
                     /translation="MNNWIEVTIKTTTEAVEPITNILYEQGAGGAVIEDPKDFLFQKK
                     NELDWDYVEEEVFKKNEEDDVLIKTYVSEEKNVMEFVEIIKQKVLGLKDFGIDIGEGS
                     VSLDQVNEADWANAWKAYYKPTKVGQRVVVKPTWEDYAMQEGDLIIELDPGMAFGTGT
                     HETTSMCIRELEKYVNKDSKVFDIGCGSGILAIAAAKLGAKEVVAVDLDEVAVKVAKE
                     NVLENKVEKSVSVMHGNLTDVIKDKADVIVANIIADIIKILAKDVQNFMKEDAIFISS
                     GIILDKVEEVKESLIENGFEIVEVQKLGEWSAIVSKLKK"
     gene            9474..10232
                     /locus_tag="ACGI5H_001767"
     CDS             9474..10232
                     /locus_tag="ACGI5H_001767"
                     /EC_number="2.1.1.193"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416604.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008168 - methyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0006364 - rRNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (uracil(1498)-N(3))-methyltransferase"
                     /protein_id="HFG9697474.1"
                     /translation="MDRFFVEKNNINLQDKTCTIEGEDVKHISKVLRCKLGEKLEICD
                     KNNNEYICEIMNIDKSIVNLEILEKVDINRESELKVRLYQGLPKAPKMEIILQKLTEV
                     GVEEIILVQTKRSVVKVDDKKEDKKFERWERIIYEAAKQSKRGKIPKLRGVLSFKEAL
                     EDMKKNSVNICPYENERTVSIKHALKKCDSNIDSVGIFIGPEGGFSEEEIEQIQKNNC
                     NVVSLGPRILRTETASVVASTIALYELSDLGGEK"
     gene            10234..11532
                     /gene="mtaB"
                     /locus_tag="ACGI5H_001768"
     CDS             10234..11532
                     /gene="mtaB"
                     /locus_tag="ACGI5H_001768"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454735.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0051539 - 4 iron, 4 sulfur cluster binding
                     [Evidence IEA];
                     GO_function: GO:0061712 - tRNA
                     (N(6)-L-threonylcarbamoyladenosine(37)-C(2))-
                     methylthiotransferase [Evidence IEA];
                     GO_function: GO:1904047 - S-adenosyl-L-methionine binding
                     [Evidence IEA];
                     GO_process: GO:0006400 - tRNA modification [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (N(6)-L-threonylcarbamoyladenosine(37)-C(2))-
                     methylthiotransferase MtaB"
                     /protein_id="HFG9697475.1"
                     /translation="MKKVAFYTLGCKVNQYETEAMLELFEKDGYEQVNSEEYADVYVI
                     NTCTVTHMSDRKSRQYIRRVKKKNPDAIIAVVGCYSQVSPEEILDIEEVNLVMGTNDR
                     RKIVEEIKKINSSKKVSTVDDIMKVKAFEEIEISQTNGKTRAFMKIQDGCDRFCTYCI
                     IPYARGRVRSRDIDSIVDEVKKLANNGYKEVVLTGIHVASYGKDLKDRDIKLLDVIKQ
                     INQIEKIERIRLSSVEPILFTDEFVNEVLKMDKVCPHYHLSLQSGCDETLKRMNRRYT
                     TLEYKTIVDRLRSKMPDVAITTDVIVGFPGETNEEFKKTYEFLKEIELSQMHIFKYSP
                     RKGTPAATMENQVDPQMKHFRSEQLLNLSKVNFNKFATKFIGRELDVLFEQNIEGNKY
                     EGLTSNYIRVVVESDKNIQGQILKVKINDVKDEYVEGILL"
     gene            11575..11925
                     /locus_tag="ACGI5H_001769"
     CDS             11575..11925
                     /locus_tag="ACGI5H_001769"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430911.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine triad nucleotide-binding protein"
                     /protein_id="HFG9697476.1"
                     /translation="MDCIFCKIANGEIPSTKVYEDDRVLAFNDLNPVAPYHILVVPKK
                     HYDSLIDIPDKEMDIVSHIHVVINKIAKEKGFDQTGFRVINNCGSDGGQEVKHLHYHI
                     LAGKKLPNYEAGQN"
     gene            12088..12267
                     /gene="rpsU"
                     /locus_tag="ACGI5H_001770"
     CDS             12088..12267
                     /gene="rpsU"
                     /locus_tag="ACGI5H_001770"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416618.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S21"
                     /protein_id="HFG9697477.1"
                     /translation="MSEVRVRENETLDSALRRFKRQCAMSGIMSEVRKREHYDKPSVK
                     RKKKAEAARRKNAKK"
     gene            12297..12740
                     /locus_tag="ACGI5H_001771"
     CDS             12297..12740
                     /locus_tag="ACGI5H_001771"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430905.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GatB/YqeY domain-containing protein"
                     /protein_id="HFG9697478.1"
                     /translation="MSLKQKLQEDLKSSMKNKDTVRKSVVTLIRASIKQYEVDNRVEL
                     DEDGIIDVIAKQLKQRRDALVEFEKAGREDLIKETEGEIEVLKEYLPQQLSEEELEEI
                     VKSTISEVGATSMKDMGKIMSVIQPKVKGRADGKLINKLVKQNLQ"
     gene            12851..13348
                     /locus_tag="ACGI5H_001772"
     CDS             12851..13348
                     /locus_tag="ACGI5H_001772"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416623.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TspO/MBR family protein"
                     /protein_id="HFG9697479.1"
                     /translation="MIISVKEIRNFLINIFIPLIIGYLSSILTMIISGTDISTYYLQL
                     TKPSFAPPAFIFPIVWTILYILMGISSYLILRKGYNLPKVRDAIFYYGLQLVLNFIWS
                     ILFFGFGLRFTALIDIIIMILVSIIMISKFSKIDKRSGYINLIYLMWLVYAGFLNYFI
                     WFINK"
     gene            13541..14104
                     /gene="raiA"
                     /locus_tag="ACGI5H_001773"
     CDS             13541..14104
                     /gene="raiA"
                     /locus_tag="ACGI5H_001773"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430900.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0045182 - translation regulator activity
                     [Evidence IEA];
                     GO_process: GO:0009386 - translational attenuation
                     [Evidence IEA];
                     GO_process: GO:0036211 - protein modification process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome-associated translation inhibitor RaiA"
                     /protein_id="HFG9697480.1"
                     /translation="MQIIVSGRQMKLTDGIKGYVDGKLSRLEKYLDPESEVKVTVSAK
                     KDRQKVEVTIIPINGQIIRAEDVEDDLYAAIDIVCDKLSRQVVKYKTKVKDKVQNNKS
                     IRFENLDFIDNSSEFDDYDYDDEEDENIVIERRKKFNVKPMSSEEAILQMELVGHNFY
                     MFRNQDNFEINIVYKRKAGGYGLIEQD"
     gene            14317..14553
                     /locus_tag="ACGI5H_001774"
     CDS             14317..14553
                     /locus_tag="ACGI5H_001774"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890653.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YabP/YqfC family sporulation protein"
                     /protein_id="HFG9697481.1"
                     /translation="MLEISTDLQVNQPVITVTSNTFISIENYLSILEYEVDLIRIKTK
                     VKTIKISGDKLSLKYITDSEIGIKGIIYNVEYVD"
     gene            14566..15909
                     /gene="yqfD"
                     /locus_tag="ACGI5H_001775"
     CDS             14566..15909
                     /gene="yqfD"
                     /locus_tag="ACGI5H_001775"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890651.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003674 - molecular_function [Evidence
                     IEA];
                     GO_process: GO:0030436 - asexual sporulation [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sporulation protein YqfD"
                     /protein_id="HFG9697482.1"
                     /translation="MISFIRGYYVIVVEGVGLEQFLNHLIRNGISVYNVTRIKNTKME
                     FHIDRQDIKDFKNVYRGSKFDIKVKQKTGVPFIIKRVYKHKGMWICALVSLFLLMSTS
                     QFVTDVYIQSPEGIKKEALRNELYKVGVRPGVYKKSIDRKEVRDHMMSKFNDVAYLSI
                     NVKGTNIFVTVTKKAESLKSTDQSNYCNVIALKNGIIEKVIPRSGKSVIKSGDIVQKG
                     DVLLNGANTKSIPEVWASTFYESTKKASYVDTVNKKTGEKKNIYTLSFYDKEFTMRKN
                     IKYKDYVVENKEKKLSIGNYTFPIKIKTSTFYETKKVEVKRNKEELKKELSEKALKEL
                     EYIIPASARIIDVKHNFKVNKNMLEYLITVQTSENIAKIYPLSKSEAERFIKEESKPD
                     EGEEEVPSNPEKRPLNDIRNEFDEDNKDNKDQNNSDENNSNQNSNNSQNNNSNNN"
     gene            15848..16963
                     /locus_tag="ACGI5H_001776"
     CDS             15848..16963
                     /locus_tag="ACGI5H_001776"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430896.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PhoH family protein"
                     /protein_id="HFG9697483.1"
                     /translation="MKIIVIKIVIIVKIIIAITTNKIKLKILGGLIQLIIQKKFTIAD
                     GNFERELFGNFDENVKLIEKTLNIDVILREGNIILIGEEKNVDSALKLMNELHQTVSN
                     GKHLDKQSISYSLSLLLEGSEQKIKELEGTIVITQRGKAVQPKTLGQKEYIKLIENND
                     ITFGVGPAGTGKTYLAVAMAVKAFKRDEVSRIILTRPAVEAGESLGFLPGDLKDKVDP
                     YLRPLYDALFEMLGADKFNKYLERGTIEVAPLAFMRGRTLDNSFIILDEAQNTTSEQM
                     KMFLTRLGFGSKAVVTGDVTQTDLPQNKKSGLIQATEILKGVPGIGSIMLTDRDVVRH
                     ELVQRIIRAYEKHDKREEFKKEERKKAKMQEKTFKRK"
     gene            17020..17481
                     /gene="ybeY"
                     /locus_tag="ACGI5H_001777"
     CDS             17020..17481
                     /gene="ybeY"
                     /locus_tag="ACGI5H_001777"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416637.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004540 - RNA nuclease activity [Evidence
                     IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0042254 - ribosome biogenesis [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="rRNA maturation RNase YbeY"
                     /protein_id="HFG9697484.1"
                     /translation="MDLILDDRQDKLEVSEELIEKIKDIIIECLDYEGYDDNYEVSLS
                     FVDNKEIHELNREYRGVDRVTDVLSFPLLSDDFEDVELEEESLGDIVVSLERALEQSI
                     EYNHSFEREVCFLICHSMFHLLGYDHDTDENTKEMREKEEHILNKLNITRE"
     gene            17487..18206
                     /locus_tag="ACGI5H_001778"
     CDS             17487..18206
                     /locus_tag="ACGI5H_001778"
                     /EC_number="2.7.1.107"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416641.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004143 - ATP-dependent diacylglycerol
                     kinase activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0006654 - phosphatidic acid biosynthetic
                     process [Evidence IEA];
                     GO_process: GO:0008654 - phospholipid biosynthetic process
                     [Evidence IEA];
                     GO_process: GO:0016310 - phosphorylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="diacylglycerol kinase"
                     /protein_id="HFG9697485.1"
                     /translation="MKPEKTRQGIIKAFNAAIEGILYTFKFERNMKIHYLGSVAVLII
                     SLFFNFSKLEMIMLLMSICLVVVAEMFNTAIEKAVDLVTDEYHVLAKIAKDVAAGGVL
                     VAALNSVVVGYILFYDKLTDISGILIYKIRESELHITLICILLVLIAVVVVKALTSTG
                     TPLKGGMPSGHAALAFAIATAITLMTERVVASTLAYIMAVLVAQSRIEGKIHTFWETI
                     AGALLGVLIAILVFQLGMFYN"
     gene            18325..18726
                     /locus_tag="ACGI5H_001779"
     CDS             18325..18726
                     /locus_tag="ACGI5H_001779"
                     /EC_number="3.5.4.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890647.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004126 - cytidine deaminase activity
                     [Evidence IEA];
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA];
                     GO_process: GO:0009972 - cytidine deamination [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cytidine deaminase"
                     /protein_id="HFG9697486.1"
                     /translation="MDNIELLRLAEDARQHSYAPYSGFRVGAALLTKSGKVYTGCNIE
                     CASLGGTNCAERTAIFKAISEGDKDIYKIAIASDNSENNEQTYPCGICRQVIIEFGSD
                     IKIITGYTKGEVFEHSIKDLLPNYFSGNDLK"
     gene            18790..19683
                     /gene="era"
                     /locus_tag="ACGI5H_001780"
     CDS             18790..19683
                     /gene="era"
                     /locus_tag="ACGI5H_001780"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897628.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GTPase Era"
                     /protein_id="HFG9697487.1"
                     /translation="MFKSGFVSIVGRPNVGKSTLMNNVVGEKIAIMSDKPQTTRNTIQ
                     AVYTDEEMQIVFLDTPGIHKPKNKLGEFMVKAATEAFKNVDLILFVVDDSKKIGPGDR
                     KIIEDLRSVKTPIILVVNKIDQLDQKDELFDIIKMYDREGIFKEIVPISALKGKNTDT
                     LIKVIQNYLEEGPKYFPDYMITDQPERVLIAELIREKVLHYLNDEIPHGVAVEIEKMK
                     ARNDKEIVDVSAVIYCERDSHKGIIIGKNGRKLKGIGKSARQDIELLLGSQINLQLWV
                     KVKENWRNLQNYINNFGYNDK"
     gene            19695..21074
                     /gene="mgtE"
                     /locus_tag="ACGI5H_001781"
     CDS             19695..21074
                     /gene="mgtE"
                     /locus_tag="ACGI5H_001781"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416647.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0015095 - magnesium ion transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0015693 - magnesium ion transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="magnesium transporter"
                     /protein_id="HFG9697488.1"
                     /translation="MDRKLDASQDLLYEVKSLIDNNKVLELRELIEEYHIIDIFDIME
                     NLEEDMKIQLFEVLPLDMASSILEEGSVEFFISILSKLDVEHSKNILELMSLGDMADK
                     LSELEEEEREHIINLLNQENADYVKELLFYDEDSAGGTMTTGYISINKDMTALEAIDH
                     MREEAEEAETIYYIYVVDDEEKLVGVLSLRELIIARDANIVEDLMSENIISVYVDEDR
                     EEAVRLVSKYNLIAIPVVDRQEKLKGIITVDDIIDVMEEEATEDMYKFAGSSEHEREV
                     AEKENPTLREQIISALRGRLPWLIITLVGGLLASLILSNLDYIMNPVYAPLVFFIPVV
                     IGMGGNIGTQSSSVTVITLSNKDLNFSNVVREGIVGIITGLLCSIITGIVIYFVMRKL
                     DIVLIVSISLFINMVLGATIGAFMPVLLKKMDADPSTVSSPIISTALDITGIAVYFII
                     TTALLSKIV"
     gene            21147..21302
                     /locus_tag="ACGI5H_001782"
     CDS             21147..21302
                     /locus_tag="ACGI5H_001782"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416649.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YqzL family protein"
                     /protein_id="HFG9697489.1"
                     /translation="MNNISWEVFKKTGSIDAYLYFCDCKNIHEEIEEVREKKEDDDNP
                     EHPGDST"
     gene            21268..22041
                     /gene="recO"
                     /locus_tag="ACGI5H_001783"
     CDS             21268..22041
                     /gene="recO"
                     /locus_tag="ACGI5H_001783"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430885.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RecO"
                     /protein_id="HFG9697490.1"
                     /translation="MIILNTQGIVLKAIRYKESDIILTLFTRKLGKVSAIAKGAKKNK
                     SSLLSSSQLFSYSNFTLKKQGNMYKVTQSEIIKSFYNISYDIEAFSYATYITKLVENS
                     ILENQTNNRLFILLAQTLYLYTQDNTDNRFITAAFELKFLDYIGFKPIVNKCINCECK
                     ILQNSVFNIYEGGILCSKCSKLFDNNIKLDLTTISLMEYVLRNDILTCSKAKVSKYIT
                     HELENILDKYLKVYVDNINFKSLHVLQSVKNNKGVDNDE"
     gene            22034..22633
                     /locus_tag="ACGI5H_001784"
     CDS             22034..22633
                     /locus_tag="ACGI5H_001784"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890640.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4342 domain-containing protein"
                     /protein_id="HFG9697491.1"
                     /translation="MSSNITIEMVDSVFERVPGATYAEAKEALVMCNGDVIEAVIYLE
                     NKKNTCNCKAKSAKETMEEVFGKDGENIKFQLKELLRKSSVVRIIVEKDGKTMMNIPL
                     TVGVVGLAFVPLATLVGLSAAVISKYRIKVQNEEDGEIVDLGELNEEKLHVLKNMITN
                     AAKDVKDVVVDKKEDDKDVTADLMKEESEKNKEDEDENK"
     gene            22793..23671
                     /gene="glyQ"
                     /locus_tag="ACGI5H_001785"
     CDS             22793..23671
                     /gene="glyQ"
                     /locus_tag="ACGI5H_001785"
                     /EC_number="6.1.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416656.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0004820 - glycine-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006426 - glycyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycine--tRNA ligase subunit alpha"
                     /protein_id="HFG9697492.1"
                     /translation="MNFQEMILALQKYWSKQGCIMMQPYDIEKGAGTMNPNTFLRSLG
                     PEPWQVCYVEPSRRPADGRYGENPNRLYQHHQFQVILKPSPDNIQELYLESLKEIGID
                     PSEHDIRFVEDNWEAATVGAWGLGWEVWLDGMEITQFTYFQQVGNIECELETGEITYG
                     LERLAMYIQEVDSVYDLKWNDKITYGEVFNKAEYENSMYAFELCDADMLFNLFDIYEK
                     EALRLMENGLVIPSYDYVLKCSHAFNTLDARGAIGVSQRASFIGRVRNMAKTVAETFV
                     KQREEMGFPLLKDGDK"
     gene            23671..25737
                     /gene="glyS"
                     /locus_tag="ACGI5H_001786"
     CDS             23671..25737
                     /gene="glyS"
                     /locus_tag="ACGI5H_001786"
                     /EC_number="6.1.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903195.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0004820 - glycine-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006426 - glycyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycine--tRNA ligase subunit beta"
                     /protein_id="HFG9697493.1"
                     /translation="MKNYLLFEIGVEEMPSRFVGSTLEQLKNNLSKLFDENRIAFDKI
                     NAYGTPRRLTLVVEGLSDRQNDLEEEIKGPAKKIAVDAENNLTKPALGFIKSKGLSES
                     DIYFKQVGKEEYIFATIKQDGKETSEVLKDILPETIKSVVFPKAMRWGGKNLKFARPI
                     RWIVALLNDKVLEFDLEGIISSNVTKGHRFLGESTIEVDSIEDYFEKLEKNYIVLDQN
                     KRKEMIRKQCIEVANSLGGEVEFDEDLLEEVTYLVEYPTAFYGEFDVDYIKLPKEVVI
                     TPMKQHQRYFPVLKEGKLLPNFIAVRNGDSYRIDNVKAGNEKVLEARLADALFFYRED
                     TKRNLESYIEKLKTVVFQVKLGTIYDKTLRLEKLSADILDSLGLVDEKADTIRAAKLS
                     KADLVTGMVGEFDELQGFMGKEYAKVGGENDVVSEAIFEHYLPRFAGDILPKTNAGVA
                     LSIADKLDSIAGFFAIGIQPTGSQDPYALRRQALGILSILMDRKVAVDIKVLIEHALD
                     NYSELDFNKEEVVEQIMNFFNERVKNLFKDLGIRYDVVDAVLSSDINDVSDMHMRALE
                     LNNWLEKDELVEMLTAFNRVSTLAQKAESDKIDESLLKEDAEIKLYNEFKQVKVKVNE
                     LLKDKKYGIALDEFASLRPVVDNLFDTVMVMDNDEAIKNNRLALLKQVYDTMLGICDL
                     SKIVYK"
     gene            complement(25903..27450)
                     /locus_tag="ACGI5H_001787"
     CDS             complement(25903..27450)
                     /locus_tag="ACGI5H_001787"
                     /EC_number="1.8.7.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454727.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0020037 - heme binding [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_function: GO:0050311 - sulfite reductase (ferredoxin)
                     activity [Evidence IEA];
                     GO_function: GO:0051539 - 4 iron, 4 sulfur cluster binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="nitrite/sulfite reductase"
                     /protein_id="HFG9697494.1"
                     /translation="MDNFKKILLNELPNFKEYSSKFLNGEINKMQYKGFSGGYGVYAQ
                     RDKKSFMIRLRVSAGVLSQYQLNKIYEIAIKHNLDKIHLTTRQAIQLHDLSINSIVDI
                     MEEGIKNDIFTRGGGGNYPRNVGLSPLSGVDPSEVFDVTPYAVATDKYFIKNATTYHL
                     PRKLKVSYSNCYTDTAHCSIQDLGFVATLKNDEPYFRVFLGGGLGKQPKVALELDELI
                     KPKDALYCVEGMIKFFMDYGNYENKNRARVRYMVESLGEKLFLEKFKEYYKLEKENGS
                     LELNIEEIDYSKPGVKIDIQDSRLIPQKQDGLYTVYIHPVGGILLTKDLSTLLKELDN
                     IENPMIRLGMTEGLYILNLNGNEAKRILEISKTISCNSQLEQSISCIGVPICQMGIQN
                     SQKMLHEIIDYFRLQNNKEILNKAPKLYISGCLNSCGVHQVGSIGLCGKKKNVDGIST
                     DAFELFVGGSFEIGKTRLGKSLGDFKASDIPEMLYKISDASSGNFYEWVNSNDNILNK
                     ITDKYKI"
     gene            27730..28497
                     /locus_tag="ACGI5H_001788"
     CDS             27730..28497
                     /locus_tag="ACGI5H_001788"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416661.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="IclR family transcriptional regulator"
                     /protein_id="HFG9697495.1"
                     /translation="MGEIINALDRALDIILLLYHEKREMGITEISKAMGVYKSTVHRT
                     LVTLENKGFVIQNAENGKYWLGINLYAIGMVVGEKMSLTEIVKPYTKKLNQEFNEVVN
                     VSILEERAQDSPRSIIIHKEYGSNQLLSVNPSVGSSSECYCSAVGKCLMAFNDSIDFE
                     KYRKTPIHKYTEHTIDNWDDMMLFLAKIKEQGYAIDDEELEHGLTCIGAPILDKNNKA
                     IAAISLSGPTIRMREGDFEYKIKRVIETAKSISELFR"
     gene            28780..28977
                     /locus_tag="ACGI5H_001789"
     CDS             28780..28977
                     /locus_tag="ACGI5H_001789"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416663.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4Fe-4S binding protein"
                     /protein_id="HFG9697496.1"
                     /translation="MEKVKLSVERCKGCYLCIEACKKDAISLSDYTNKKGFVTIKVDE
                     EKCIQCGACYTMCPDLVFEIL"
     gene            29006..30082
                     /gene="vorB"
                     /locus_tag="ACGI5H_001790"
     CDS             29006..30082
                     /gene="vorB"
                     /locus_tag="ACGI5H_001790"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890635.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-methyl-2-oxobutanoate dehydrogenase subunit
                     VorB"
                     /protein_id="HFG9697497.1"
                     /translation="MQSLLIKGNEALAEGAIRGGCRFYAGYPITPQSEILEMMAWRQK
                     EVGGVFIQGESEIASVNMVMGASALGARAMTSSSGPGFSLKQEGIAYWVSAGLPAVVA
                     CVQRYGIGDGFIGAGQDNYWQAVKGGGNGDYHLIVLAPNSVQENMDMAYESFELAEKY
                     MHPVLILSDATIGQMVEPCIAPPMKEYDMDKAPWAAKGTPVGEKNKVITDITYFEDQD
                     TWQKGYIEKMRKVQEDEQRWEEIEIEDAEVVFVAYGISSRIAEGAVRDARAKGMKLGL
                     IRPKTLWPYPRKAFKKLSDSLKGLVTVEMNMMAQMKEDVIIACDNRFPVYSVATAQYM
                     AEVNQLIDFAQQIIDGKAKQEEVF"
     gene            30085..30804
                     /locus_tag="ACGI5H_001791"
     CDS             30085..30804
                     /locus_tag="ACGI5H_001791"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454726.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003824 - catalytic activity [Evidence
                     IEA];
                     GO_function: GO:0030976 - thiamine pyrophosphate binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="thiamine pyrophosphate-dependent enzyme"
                     /protein_id="HFG9697498.1"
                     /translation="MAKKAPAIMMCENMFCGGCGHSIVDRIIGEVLTEMDICQDTIIC
                     SDIGCNHMFQFSMNVDVVVPPHGKMGAAMAAMKRVRPDKYIFTIAGDGGAYAIGLGET
                     MSAATRNDNVIFLVMNNNMFAMTGGQMAPTTIEGQYTASTPAGRNYADHGSTFDVVKV
                     MGNLDIAYLARGTITNPKEINTTKRYIKKALEKQKEKKGFCLIEVLVPCPTNWGLKPV
                     DAMKRIENELVPKYPLGEFID"
     gene            30817..31356
                     /locus_tag="ACGI5H_001792"
     CDS             30817..31356
                     /locus_tag="ACGI5H_001792"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416670.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016903 - oxidoreductase activity, acting
                     on the aldehyde or oxo group of donors [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="2-oxoacid:acceptor oxidoreductase family
                     protein"
                     /protein_id="HFG9697499.1"
                     /translation="MLNEIICAGFGGQGVLTAGKIIMYVAYKAEKKITWFPSYGNEMR
                     GGSANCNVVVSDEKIANPCVKNPDILLGMNSVSVDKYESLMKKNGYMFVNESLVSKDR
                     KYREDINVIKVPVTEIAQNLGNEKAANICMLGAMVKSLDLFTKEEFESGMCEYFENQG
                     KGKFNSKNVEAFEAGYDYE"
     gene            31513..32571
                     /gene="buk"
                     /locus_tag="ACGI5H_001793"
     CDS             31513..32571
                     /gene="buk"
                     /locus_tag="ACGI5H_001793"
                     /EC_number="2.7.2.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430878.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0047761 - butyrate kinase activity
                     [Evidence IEA];
                     GO_process: GO:0006113 - fermentation [Evidence IEA];
                     GO_process: GO:0016310 - phosphorylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="butyrate kinase"
                     /protein_id="HFG9697500.1"
                     /translation="MKVLVINPGGTSTKISVFQDENEILKKNITHTREDLKNFSKVFD
                     EYDYRKQLIVDILSSENHSINSFDAVVGRGGLMKAIKGGTYTVSEEMIEDMRNEINGE
                     HASNLGALLAKTIADEIGVQSFVVDPVSVDEFDDVSRITGISDIEKASWLHALNHKAV
                     SRKIAQKLGGKYEDYNFIVAHLGSGISIVAHKQGKMIDGSGGRSDGPFSPERSGGLLA
                     YPLIELCYSGKYTHDEMVAKVSSIGGMYDYLGTKDMIEIENRIKEGDEKAKLIMDAFI
                     YQVAKEISMYGASLSGNVDRVILTGGISHSEMVVKGVAEKVSYLAPIEIVPGEMEMEA
                     LALGALRVLNGEEIAKTY"
     gene            32589..33482
                     /locus_tag="ACGI5H_001794"
     CDS             32589..33482
                     /locus_tag="ACGI5H_001794"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454723.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016746 - acyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional enoyl-CoA hydratase/phosphate
                     acetyltransferase"
                     /protein_id="HFG9697501.1"
                     /translation="MLKDFNNLLEEAKKLEPVIVSVAVAEDKEVLKAVKSATDLNIIK
                     PILVGDKDKIESISREIGLKGHEIIGCQNPDESVKKAVEIVKNKEAKVLMKGLVNTSV
                     YMRAILNKETGLRTGRLLSLLAVYELPQYHKLLYCTDSGINVSPNLNQKKDIMTNALL
                     TMKSIGMENPKTAILTANEMVDPKIQSTVDANLLVEMEKSGEIPKCIVEGPIAFDVAF
                     DAHAAEHKGIKSNIAGDVDLLVFPNIEAGNILGKSWLRFNKAKWAGIVLGATNPIILG
                     SRSDTAEIKINSIALACLASQ"
     gene            33512..34720
                     /locus_tag="ACGI5H_001795"
     CDS             33512..34720
                     /locus_tag="ACGI5H_001795"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890629.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PLP-dependent aminotransferase family protein"
                     /protein_id="HFG9697502.1"
                     /translation="MKYAKRMDMVKASAIRDSQKKIAQKVASGGTVISFAAGLPDPNL
                     FPIEEISEITQKVLNERGKFALAYGPTKGEDELLDLLVKRMKEEENIDTKAENIIITT
                     GSQQGIALSAMILLEKGDVVVTENPSYLGAINAFRPYECDFLGVDTDEEGMVTDDLDK
                     LLSENSNIKVIYVIPTFQNPTGKTWSLQRRKDFMEVVNKYDVIVIEDNPYGEIRFTPE
                     PLPTLKSLDTKDKVLYLGSFSKVLCPGFRVAWMCGNVDIIDKAELLKQGIDLQSNQFS
                     QVQVIEFLKKYNLNEHIEKIRAEYKKRCLLMLDAMKKHFPEEAKYTEPDGGMFIWVEL
                     PESINVDDLLDKAIDAGVAYVSGESFFANNGPKNTMRLNYTTMSEEQIVKGVEILAEV
                     IKKELNYACE"
     gene            34744..36003
                     /locus_tag="ACGI5H_001796"
     CDS             34744..36003
                     /locus_tag="ACGI5H_001796"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454721.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HFG9697503.1"
                     /translation="MGEKENGIKFGKLMFQLVIIAISWELVYIIPFIQYTLYDPILKA
                     LECTNTQLGFLLTIYGLGNIFGAPIGGWLADRFDYRKIILGSVFLNGVVSFLFAFNMN
                     YPFAVATWVGCAITSLVMNYPSMVKILRVIGKDNQGKVYGFNEAMVGVSGVVMGAIFL
                     YIYTCFATPTLGMRWVMISLGILSIAMCPVLWFVIKDVDIKEEREEAGEKMSAGDFIT
                     VLKSPNTWLVGISIFCVYSFTVTMSYFTPYITSVLGGSVALSGALAIIRQHGLKLFGA
                     PFGGYCADKLKSPTKVLLPIYVFGIAVIVLFLVLPASTPMTIFIALTFVVGILGYMGK
                     GIYYAVQDEVKVPVKYSATTIGIAAALGFSPDVFQFALIGHWIDTYGNKGYTYTFIFQ
                     IAILVIGILSCLYILKVKKRRASKLEA"
     gene            36648..38111
                     /locus_tag="ACGI5H_001797"
     CDS             36648..38111
                     /locus_tag="ACGI5H_001797"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018112852.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0005283 - amino acid:sodium symporter
                     activity [Evidence IEA];
                     GO_function: GO:0015293 - symporter activity [Evidence
                     IEA];
                     GO_process: GO:0006814 - sodium ion transport [Evidence
                     IEA];
                     GO_process: GO:0006865 - amino acid transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="alanine/glycine:cation symporter family protein"
                     /protein_id="HFG9697504.1"
                     /translation="MTDLVNTINGIVWSPVLVAMCLCIGLYFSLKLKFFQIRDVKEMF
                     TLLLEGDSSHVGISSFQGFATSMAGRIGTGNIAGVAVAIAMGGPGALVWMCIMATLGS
                     ATAFVESTLAQIYKDEHDGQYRGGPPYYFEKGLGWKKCSVLFSIVAIISYTFFMPGTQ
                     SNTLYLAMNQAFGFSKMTIAVASSIALAIIIFGGIKRIGLFAEKVVPIMGGAYLIMTL
                     VIIITNISLVPEAIVTMFKSAFGFGSVFGGMLGSAISWGVKRGIYSNEAGEGSGTYGA
                     AAAEVSHPAKQGLVQAFSVYVDTLLICMATGIMIVITGMYNVTGVCTALPGVEPGPQY
                     VQSAINTLHPQLGDIFIAIVLLLFTFTTLLAFSYMMETNVSYLVTRIKAEKHEKYIIN
                     VCRFMLIACAAMCCFIEPLTSWALGDICIGVLTYINLIAIFTLKKPAIKAYYDYIRQK
                     KMGIKRSDRTFNPIELDIRNAEFWENRYLKEDKHELN"
     gene            38167..39303
                     /locus_tag="ACGI5H_001798"
     CDS             38167..39303
                     /locus_tag="ACGI5H_001798"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905908.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M20 family metallopeptidase"
                     /protein_id="HFG9697505.1"
                     /translation="MKERIIQVADSKKEKILGLCQSLYDEPEIALQEYKSAKKISEFL
                     REEGFDVEENLAGMATAFKATKKNGDGPKIAFIAEYDALPGNGHACGHHLIASMGVGA
                     GIALSSILDTYKGEVSIIGTPAEETGDGKPYLIEHGVFDGYDAAMMIHPNSKTCVTPE
                     IIAIGGLDFIFTGKASHAGAKPYNGINALDAVVLLYNNINALRQQLVDGTRIHGIILE
                     AGTAANVIPDMGKVRLEIRAKEQNYFDEVVEKVKNCARGAAIATGCELEFYHFEPTCQ
                     GLNENKVLVDIFTKIMEEFGIYEDEQVMLGSTDMGNLSQIMPCIHPLMKFSENGEELH
                     TKEFLEASINSYAKDRVIDGIKILALTGFNLFENPELLKKMKEE"
     gene            39539..40654
                     /locus_tag="ACGI5H_001799"
     CDS             39539..40654
                     /locus_tag="ACGI5H_001799"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728789.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="C45 family autoproteolytic
                     acyltransferase/hydrolase"
                     /protein_id="HFG9697506.1"
                     /translation="METLEVRNIELSGTNYEIGYRLGELVANMPEIIEGQINKSNLVS
                     KKEEKEMIELFDKYCPGLNEELQGFADAIQVNCNQILYYTMTYLKPGCSQVALAPELT
                     ENGHVLFARNFDFSHNMEDFVLCKTKVNGKYAHIGTTIMQFGRGEGMNECGLGVSQSS
                     CGIPVGNSDGLRKPAIVGLQFWAVIRYLLENCKDVDEALEYLKDMPIAYNINLLLADK
                     SGNIALVETLDGKKEVNIINSLESKREYFLHSTNHTHIDKLHKLDPQSMKNSIHRYKL
                     IKEYINKSKKIGEKELMNLLSSKYPNGLSCNYYNDFFGTLKSIVMDLNIGKFNILWGG
                     LENKWESYYLKNDIKSITQRININIEKAPSDFFDFIE"
     gene            40806..41675
                     /locus_tag="ACGI5H_001800"
     CDS             40806..41675
                     /locus_tag="ACGI5H_001800"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861549.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="effector binding domain-containing protein"
                     /protein_id="HFG9697507.1"
                     /translation="MDYLKYFEKAVMYIENNLHENITVNDVAKETGYSYYHLTRLFKS
                     MFGESVGSYIKKRRLVSSTKELLYSDKKVIDIAIGSGFESSEAFSRAFKSIYKVSPIE
                     YRKNRIDVFVGKKKKLELDFMRHLVGNITIKPVIKEIEKIKVIGIKDKVILENNSLPD
                     LWEKFRKVHHIVPNTLPSRRVFGICEAISEIHLVSESMEFNEIIGLEVNSYDVIPNSF
                     VSKTIKEGKYAIFTHTGSLDNLDKTYEYIWGTWFLSSKEELDIRDDFEVYDERFLGPS
                     NVNSQIDIYIPIK"
BASE COUNT        16644 a         4310 c         7634 g        13195 t
ORIGIN      
        1 aaaagttgcc ttttaaatta tcgagattat ttttatctag aaaatcaata acataaatag
       61 cattattgaa agtaactaaa tggctactag catctaactt ttggttttca tatggataga
      121 tatttatttt tttattaagc tgtctttcta aaaaatcttt taactcttcc ataaagtctc
      181 cttaaaaata agattatatt cttatcttat agctaaagta gtttctttgt caaatatgtg
      241 tactctacta ttgtcaactg aaagtgttaa gtcatcacca acattaattc tgtttttact
      301 gtcaaatcta attgttatcg tattttcgcc tagttttaag tgagcataag tttctgctcc
      361 cataagttct tttatttcaa ttcttgattt aaaacaagta tctggattag atttaataaa
      421 agtatcttct acatgaatat cttctggtct gatacctata acaacttcat tattaatata
      481 attgtctttt attaaatcat agtgtttttc tttattcaat ttaagcttaa tatgttcatt
      541 ttgtgcataa atttcatcat tttcttctat taatattaca tcaataaaat tcatctgtgg
      601 tgctccaata aatcctgcaa caaatatatt agctggataa tcgtatacat cttgtggagt
      661 tgcaatctgc tgaactactc catccttcat tactacgatt ctatcagcca tagtcatagc
      721 ttcaacttgg tcgtgtgtta catagataaa tgtagttcca agctgttggt gtagcttagt
      781 tatctctgtt ctcatagcag ttctaagttt tgcatctaag ttggatagag gttcatccat
      841 taagaatacc ttaggatttc taactattgc acgtcctaag gcaacccttt gtctttgtcc
      901 tccagataat gttttaggtt ttttatttaa aagaggtagt aagtctaata ttttagcagc
      961 ttctttaact tttttgtcta tttcatcttt aggcaaattt ctaagtttaa gtgcaaatgc
     1021 catgttttcg taaacagata agtggggata taaagcatag ttttgaaaaa ccatagctat
     1081 atctctatct tttggttcta tattattgac aagtttatct ccaatgtata gttctccttc
     1141 agagatttct tcaagaccag caatcattct aagtgtagtc gatttaccac aaccagatgg
     1201 tcctactaaa acgataaatt ctttatcttt aatgtctata tttatatttt ttactgcgtt
     1261 aaatccattt gagtaaagtt ttgatatatt ttttaaaatt acttctgaca taatatcctc
     1321 cttgatattt aaattttaat tatatagtat caaatttttt tattatatta aatgtgtaaa
     1381 atgactaaat gtatttgttt aatatgtata tttagttttt agcaaagaat aaaactaaca
     1441 gtagaatata tttaaaaaat taaaaaacaa aattaaattt attatcaaaa aatcatttta
     1501 tgatatgttt tatttttata ttacaaatag agaataatga attatactag aaagtaggag
     1561 gtgaaaatat gagcagaatt tcaattttta tggaatcatg taatggcaaa tttccaaatg
     1621 aaaattcaat gttgtcagtt tcctttataa aaaatatttt aaatgcagaa aacaaagatt
     1681 ttgctaaaaa catatttaac tatggggaag aaagaaaaaa caataagcaa ataaaggata
     1741 taaatacagc catttacata ccaaatctta taagaagcaa aaatgagtta cttgttgatg
     1801 gagatataat attcaatata agtttttata attattctat gttcagtaaa ttatacaatg
     1861 gaattttaaa agtaaaggag ctagaatata aaggttatag atttaaaata aaaaatataa
     1921 aaatacataa agaacacgag ataaaagaaa atggtgttat atttaaaact atgtctccta
     1981 taatagtaaa gaataaagaa ggtaaatatt tagatgtaga agattcaaat tatatagaat
     2041 gtttaaacta tatagctaat ctaactctgg agagtataag aggtagtggg cttagaaagc
     2101 cattggaatt tatacctatt aacttcaaaa aaagagtgtt aaaagaaaag attcgtggat
     2161 ttaaagtgag agaatattac tatataaatg cttatgcagg aacatttttt ttaaaaggag
     2221 atatggaaga tttaaatgca ctgtataaaa tgggaattgg atatagaagg acagaaaatg
     2281 caggaatggt tgatatatta aagtagcgag gtgagagaaa taaaagctaa attttataga
     2341 tcaggtgata ttgtaagaga tattggcatt gtttactttt atgaattact aatggattta
     2401 aaaaacgaac tagaaaaaaa tgattataag ctaaaattta cttgtgagtt aaatagaaat
     2461 tatttatctt tagaatctgc agaatatata gaccctaagt atatatctga ttatatatta
     2521 gaaaatcgac tttttaaggt atttaaaaat gggaaaaagg aaaccttaga aaaaatattt
     2581 agtaatatag ataatttaac gtatgtaaat tttattgaag aattagataa atcttctgca
     2641 actgctaaac aaaaggaaga tattaaaaaa gattttaaaa acaggaggtt tccatatgtt
     2701 agaaatagtg gtaagtatgg attaaacacg agtttagaaa atatggaaac aaatgtaaaa
     2761 agaatagtag atactgtaat taaatcaaat atagagatag atgaaataga taaacttgat
     2821 ttgacacaat atgaagaaaa agatagtgta tgtaatgttt gcaatataaa taaaacaaca
     2881 aaactagata ttgatttaag agaacgaaag gactctaagt ataacttttt atttagaggt
     2941 gcagaaaaat caggctttaa aagaagtgga caagttgaaa gtaatatttg ttttgagtgt
     3001 gaatttttca acttaatgtg tcttttatat ataaatttaa aaagaccaat ggtttttgca
     3061 tatacgaatg atttaagaga attagcattt ttaaatcata agataatgct taaaagaaaa
     3121 atgtattcag ataaatcatt ttataaaaaa cttttgcatg aaaaaataag ttcaattaga
     3181 ctatatagct ttgatattga tacgaataaa ggtataattc taaagtttga ttctattata
     3241 gagtataaag aattattaaa aaaaattgaa cttatagata ttatagataa ttataatttt
     3301 tcaagagagc caggtaatac tagaaatttg ggtaaaagaa tgattgataa tgggaattta
     3361 tcaaatttaa aagaattatt acttgataat ataagtgttt taaagcaatc aactggaact
     3421 tctcgagaaa tggattttgt atctagctca tataatatcg gtttatatat aaaattgtgt
     3481 tggattgtag atggagggga ggagtataaa atgaaaaact atatggaaag taatttaata
     3541 tattcaagag taggtaaaga cttatttaat aaaatgacag atgaatccag aagaaaaaat
     3601 ttttctatga aagtgattca actacttaag tctaatgata gaactcagct atttcaaact
     3661 ataatgcatg tgttagtttc taatggaatc ttaataggag aagggtttgt agaaggtcta
     3721 atgcagagtt ctgaattaga attaaatacg aatgtaggtc tatttattca agaaatcatg
     3781 aaataaaaaa gggggaaaat ttaaaatgaa tgaaaaaaga gtaaaaggag taacattaac
     3841 tatactgaca gaaagcccag ttccactttc atatgaccaa gggtatggaa attatacacc
     3901 aataaaaaaa gaacaatata gagaaaaaat acatgcaaaa actagtatag ccacaataac
     3961 atatgattta agaagaatgc tccaccaaga atatggttgg aatttaagta atattgtttt
     4021 tggaaaaaaa ggaaatatat atccatctat taagaaaaat gtaggatgtg tagatgaaaa
     4081 tggattagag actgatgtat ttggttattt aataccactt aaagataaag gttctataag
     4141 taaagcttct ccacttagaa taataccttt taggtcatta aatccatata aaggttcaac
     4201 acagctaata acaaatagag gctttttaag tagtgaattt ggtagaaaat attatgatga
     4261 gaaggaagaa aatgaagtac ctagagatga aaactttcca acatcacaag cattagcaat
     4321 agaagagact ttatcagatt actacgttta tacaataaca ttggagcttg atagaatagg
     4381 agtagtagaa gtagaagatg gaaagttact tttaccagaa gaaagaaaat ttatgagtaa
     4441 ggagttaaga gaaaaagcag taaaagatat attagatgca attactgtgt ttacaagaaa
     4501 cataaaacat tcatcagtac tattaaaacc acttgcagta ataggtggag cttttgataa
     4561 agttgtacca tttttttggg atgatgtaga ttataatgct gatagtggtg agataaattt
     4621 agagggagtc atagaaacta tagaaagtta tagccttaaa gaaagtaaca caatacttgc
     4681 tatcaatgat agattaaaaa tttctaataa aaaggaatta aataagttta atttaagtaa
     4741 ataccctgta aaagagatta aaaatctagc agatagattg gaaattggag aagataatat
     4801 gtggtattta aaagagtagg aggttttttg aattatgaaa gtattacaat gtaaacttaa
     4861 gcaaccaact gctcactata gagacccaaa agtatttcaa aatgaatata taagtacttt
     4921 aaatttacca tctaagacca caataatggg aatgataacg tatttatgtg atagaagatt
     4981 aaactctgat atagatatag gaataattgg aacacatcat catagagaac tagaattttc
     5041 aagaggagaa aacattgatt tttggaatga atatataaaa atgggaaaag gtaaagataa
     5101 agaaaagttt ttgcttaaag gaaactacta tgattactat aaagagcata aagctcaaaa
     5161 tagcatatta aactatgaag ttcttaaaga agtagaactg actatattta tttcttgcaa
     5221 ggatgatgaa gaacttgaat ttattagaaa aaagcttgaa agtccatgta aatatgcaaa
     5281 tttaggaaga aaagaagatt ttgtaatacc aagtgaaaaa gggtgttttg tgaaagaagt
     5341 taagttaaaa gaggttatac ctatgaatac tcgtgatgct ataaaagaaa atataaaatt
     5401 aaagaataca tatgtaagag ttgacttaag agataaagag aatgtcgaga ctataataaa
     5461 tcaaggtgta ttgattgcat tgcctcataa atataaagat ttagaagcaa atagagatga
     5521 tagagtttat gagttttgcc attatatata tgttgataat gatggtatat atcctaaaaa
     5581 tattaaggta aatgtatgta ttgatacaaa agaagttttt acatggcttt aaattatttt
     5641 gaaagatagg tgtttatcat gaaaaatatc atgcaaaaag aaatattagc taagtcatac
     5701 aatttaagaa ctaatcaaca agaacaaaca ttagttgaac atattaagga tttatttgaa
     5761 gtattagaat ctatattaga attaaatcta tattcagata aagatgtaga gatactaaaa
     5821 atatgttgtg ctttgcacga tttaggaaaa attaattcaa ttatgcaaca aaaaatggag
     5881 attaataata aaatatcgta tagttgctca gaagaagaga ggaaaaagtt agagtctgac
     5941 aaaaaatctt taaaaaagat agcaagacat aatatatttt ctggagcatt tttaaaagat
     6001 atattagaaa aaatgaactt gtcagaagaa gataagttat atatatataa aagtataatg
     6061 ttacatcatg gaaactatga agattatatg aggttaagta ttagtaaagt tcaagaagaa
     6121 atttatgagt atattgaaaa aggcatttta gaaaaagaag agtttaatct gaaagatata
     6181 gaaagttata taaatagcat tttaaatgta gactttaaat ttggtgaaga tgtattggat
     6241 tatgattaca tagataaatt aagtgaaagt atgtttatag acagtgatta taacaatggt
     6301 caaatagatg attcagtttt aaattataga aagtttaagt atattttata taaagggatg
     6361 ctgaacttaa tagaccatag tgcatcaagt agacagaaag gtataaaatt ttataacgat
     6421 tttactgatg aagaaattga taatatgatt ttaaatgaga tatataagag tcagggtaat
     6481 ttggaaaaaa ataatataga gttcaatact atacaaaaaa ggttgagaga actttctgga
     6541 agaaatgttc tgactgttgc atttacaggt tcaggaaaaa cagctgcaga ttatagaaag
     6601 acttttaaaa gaaaattctt tttagtgcca aataaaatat cagcagaaag tttttataga
     6661 aaaaatattt ttcaaaataa aaatgattta gatacaagaa gtagtaatga ttacattgga
     6721 ttacttcatg gagatataaa cttatattca gagaatgaag ataatggaga acatgatttt
     6781 gtattgacat taagggatat agatttgagt ataaactttt gcaaaccttg tgtaattgca
     6841 acagttgatc agttattact tagtatgttt aaatttccgg gatatgaaaa aatattcgca
     6901 gccgtaaaaa atgcatctat aactgttgat gaagtacatt tattggaacc aaagatgttt
     6961 ttgattttga tatattttat gcagtttgca tgcaagtact tagatgttga ttttcactta
     7021 atgacagcta cacttccaaa atcatataaa gagcaaatga taaacaaggg aattattttt
     7081 caagaagaaa gtaatgaaaa tgttactgat aaaggagaaa tagtttttat tgagagcaac
     7141 aaggaagaag agatttgtga aggtaaagat gtaaaggttt cttttataaa ggaaaaagaa
     7201 atcaagtcaa tagttgaaga tgctttagaa aataaacaaa aaattcttat aataaagaat
     7261 actattgatt cagtcaatag aacatatgag tttttaaaag aaaatttatc tgataagtat
     7321 ggtggtgtag atatagatgt tttacatagt agatttaagt tcaaagataa aaaagagaaa
     7381 tatagtaaaa tattaaatgg agagggtgat atttggatat caactcaatc agtagaaata
     7441 tccttggatt tggatttcaa tataataata agtgatttag caactatgga tagcttaata
     7501 caaagaatgg gtagatgcaa tagaaataat aagtatgaat atggaaactt ttatattcta
     7561 cctagtgaag ataaaattta tgacaacaaa cttaagagca caactaaaaa catcttaaag
     7621 gacatattaa aaactaactc tatttttaca atgggaatta gaaaaactat tttggatgat
     7681 tactatgata atagtgtagt caaaaaatat tttgaagaga attttataag ttgtgataaa
     7741 gaaattaaga atatttatgg tgtaaataaa gaaatttttg atggattgga tttaattttt
     7801 aattttgaac cttacaaaaa tattgttgat agtaagaagg aagcagctaa aatttttaga
     7861 gatgttgatg ttagttacaa aattattctg gaagaagatt tttataagga agatagagag
     7921 ttacaacaag attcgattca agtatcaggg tttatattta atagattata ttattatggg
     7981 ttaataagca aagtagaagg atacatggta ctaaaatcta gtagtaagtt tgagtataat
     8041 agtactgtag gcttaatttt gaagtgagca tatgtttaaa tataatatac ctttagacat
     8101 tgaaaataca aaaagtacta ctgtaagctc actgtaaaaa ctatttttta aaaggaaaaa
     8161 taagttgtga gatagagtgt ttacaagtgt atatagataa taaatttgag gtttaagatt
     8221 aactaagtgg gtttcaggta catcgcgaaa ataattataa gttggagatt ttgtatgttt
     8281 aagattaact aagtggattt caaatattga tatagtagat ataatagaag ttttattatt
     8341 aggtttaaaa ttaactaatc ggatttttaa atattctgac tattatataa ggatattatt
     8401 agattgaatt taaaaccaat aatataaaac aacaaaatat tatatttatg atataataaa
     8461 agttatggaa aaacaggaat attactatag agaagagagg taaacttatg aataattgga
     8521 tagaagtaac tataaaaaca acaacagaag cagttgaacc tataacgaat atactatatg
     8581 aacaaggagc tggaggagct gtaatagaag acccaaaaga ctttttattc caaaagaaaa
     8641 atgaactaga ctgggattat gttgaagaag aagtatttaa aaagaatgaa gaagatgatg
     8701 ttcttataaa aacttatgtt tctgaagaaa aaaatgtgat ggaatttgtc gaaataataa
     8761 agcaaaaagt tttaggatta aaagattttg gtatagatat aggtgaagga agtgtatcat
     8821 tggaccaagt aaatgaagct gattgggcaa atgcatggaa agcatactac aaaccaacaa
     8881 aagtaggaca aagggtagta gtaaagccta catgggaaga ttatgctatg caagaggggg
     8941 atttaatcat agagcttgac cctggaatgg catttggtac aggtacacat gagactacta
     9001 gtatgtgcat tagagaatta gaaaagtatg tgaataaaga ttctaaagta tttgatattg
     9061 gatgtggtag tggaatcctt gcaatagcag cagctaaatt aggagcaaaa gaagttgtag
     9121 ctgtagattt agatgaagtg gctgtaaaag ttgcaaaaga aaatgttctt gaaaataaag
     9181 ttgaaaaaag tgtatctgta atgcatggta atttaactga tgtaataaaa gataaagcgg
     9241 atgtaatagt tgcaaatata atagctgata taataaagat acttgcaaaa gatgttcaaa
     9301 actttatgaa agaagatgct atattcatat cttcaggtat aattttggat aaagtagaag
     9361 aagttaaaga aagcttaatt gaaaatggat ttgaaatagt tgaagttcaa aaattaggtg
     9421 aatggtcagc aatagtttct aagcttaaaa aataagggat atggtgacgt ataatggata
     9481 gattttttgt tgaaaaaaat aatataaatc tacaagataa aacttgcact atagaaggtg
     9541 aagatgtaaa acatatttca aaagttttaa gatgcaaatt aggtgagaaa cttgaaatat
     9601 gtgacaagaa taataatgag tatatttgtg agataatgaa tatagataag agtatagtta
     9661 atttagaaat tttagaaaaa gttgatataa atagagaatc agaacttaaa gtaaggctat
     9721 accagggact tccaaaagct ccaaaaatgg aaataatact tcaaaaatta actgaagtgg
     9781 gtgtagaaga aataatatta gttcaaacta agagaagtgt tgttaaagtt gatgacaaaa
     9841 aagaagataa aaaatttgaa cgttgggaaa gaataattta tgaagcagca aagcaaagca
     9901 aaagaggtaa gataccaaaa ttaagaggtg ttttaagttt taaagaagct ttagaagata
     9961 tgaaaaaaaa tagtgtaaat atttgccctt atgaaaatga aagaacagtt tcaataaaac
    10021 atgcactaaa aaaatgtgat tctaatatag atagtgttgg aatttttata ggtccagaag
    10081 gtggattttc tgaagaagaa atagaacaaa tacaaaaaaa taattgtaat gttgtatcat
    10141 tggggcctag aatattaaga actgagacag cttctgttgt agcatcaaca atagctttgt
    10201 atgaactaag tgatttagga ggagaaaaat aaattgaaaa aagtagcttt ttatacactt
    10261 gggtgtaaag ttaatcaata tgaaacagaa gctatgctag aactatttga gaaagatggt
    10321 tatgaacaag tcaatagtga agagtatgct gatgtttatg ttataaatac atgtacagtt
    10381 actcatatga gtgatagaaa atctcgtcaa tatataagac gagttaaaaa gaagaatcca
    10441 gatgcaataa tagccgttgt aggatgttat tctcaggtat ctccggaaga aattttggat
    10501 atagaagaag taaatttagt catgggtaca aatgatagaa gaaagattgt tgaagaaatt
    10561 aaaaagataa attcaagtaa gaaagttagt acagttgatg acataatgaa agttaaagct
    10621 tttgaagaaa tagaaatcag ccaaactaat ggaaagacta gagcatttat gaaaatacaa
    10681 gatggatgtg acagattttg tacttattgt atcattcctt atgcccgagg acgcgttaga
    10741 agtagagata ttgatagtat agtcgatgaa gttaaaaaat tggctaataa tggctataaa
    10801 gaggttgtat taacaggaat acatgttgcc tcttatggaa aagatttaaa ggatagggat
    10861 attaaacttc ttgatgtaat aaaacaaata aaccagatag aaaaaataga aagaattagg
    10921 cttagttctg ttgaaccaat tttatttaca gatgaatttg taaatgaagt tttaaagatg
    10981 gataaagttt gtcctcatta ccatttatca cttcaaagtg gatgtgatga aactctaaaa
    11041 agaatgaata gacgatacac aactttagag tacaaaacta ttgtagatag attgagaagt
    11101 aaaatgccag atgtggcaat aactacagat gtaatagtag gttttcctgg agagacaaat
    11161 gaagagttta aaaaaacgta cgagttttta aaagaaatag agctttcaca aatgcatatt
    11221 tttaaatatt caccaagaaa aggaactcca gctgcaacta tggaaaatca agttgaccct
    11281 caaatgaaac actttagaag tgaacaactt ttaaatttaa gtaaagtaaa ttttaataaa
    11341 tttgcaacta aatttatcgg ccgtgagttg gatgttttat ttgaacaaaa tatagaaggc
    11401 aataaatatg agggattaac ttcaaattat ataagagttg ttgttgaaag tgacaaaaat
    11461 atacaaggtc agatattaaa agtgaaaata aatgatgtaa aagatgaata tgtagaagga
    11521 attttgctat aacatgtaga aattataata tttataagat aggaggtgga aagaatggat
    11581 tgtatttttt gtaaaatagc gaacggagaa ataccttcaa ctaaagttta tgaagatgat
    11641 agagtcttag cttttaatga cttgaaccca gttgctccat atcatatatt agttgtacct
    11701 aaaaaacatt atgatagttt aattgatatt cctgataaag agatggacat tgtgtcacat
    11761 attcatgttg ttattaataa aatagctaaa gagaaaggtt ttgaccaaac tggattcaga
    11821 gtcataaata attgtggaag tgatggaggg caagaagtta aacatttgca ctatcatatt
    11881 ttagctggta aaaagcttcc taattacgaa gcgggacaaa actaaactaa attattgaaa
    11941 aattgagttc cttcttgata aaaatacttg ataaaagtaa aaatttagtt tataataaac
    12001 aaagtgttag gttgtaatgc atattatgca aaaagaacat agttacagtc ccagcataat
    12061 tgcgctattg gagggaggga aaaagaaatg tcagaagtaa gagttagaga gaatgaaaca
    12121 ttagacagcg ctttaagaag attcaagcgt caatgtgcaa tgtctggcat catgtcagaa
    12181 gtgagaaaaa gagagcacta tgataagcca agcgttaagc gtaagaaaaa agctgaagca
    12241 gcaagaagaa aaaacgctaa gaaatagtag taaataagaa taaagaggtg aaggggatgt
    12301 cccttaagca aaagttacaa gaggatttga aatcttcgat gaaaaacaaa gatacagtga
    12361 gaaaatctgt agtaacttta ataagagctt ctataaagca gtatgaggtt gataataggg
    12421 tcgagcttga tgaagatgga attatcgatg taatagcaaa acaattaaag caacgtagag
    12481 atgcattagt tgaatttgaa aaagctggaa gagaagactt aataaaagaa acagaaggtg
    12541 aaattgaagt tttaaaagag tacctacctc aacaattaag cgaagaagag ttagaagaaa
    12601 ttgtaaaatc tactatatcc gaagtagggg caacttctat gaaggatatg ggaaaaataa
    12661 tgtcagttat ccaaccaaaa gttaaaggaa gagctgacgg aaaacttata aataagttgg
    12721 taaaacaaaa cttacaatag attgatatag cctagagaga aatctctagg ctttttatag
    12781 tttttgggaa taacgagtca tatttgagca tatctataat caaagaaaat tttgaaagaa
    12841 ggggaaaaat ttgattatat cagtaaaaga gattaggaat tttttgataa acatatttat
    12901 accactaata ataggttact taagtagcat cttaacaatg attatcagtg gaacagatat
    12961 ttcaacctat tatttacaac tcacaaagcc aagctttgca ccaccagctt ttatctttcc
    13021 tatagtttgg actatattgt acatattgat gggtatatct tcatacctaa tattaagaaa
    13081 gggttacaac ttacctaaag taagagatgc aattttttat tatggattac aacttgtatt
    13141 aaactttatt tggagtatac tattttttgg atttggactt agatttacag ctttgataga
    13201 tataataata atgattttgg tttctataat aatgatttcg aagttttcta aaatagataa
    13261 gagatctgga tacataaatt tgatttattt aatgtggctt gtttatgcag gatttttgaa
    13321 ctattttata tggtttatta ataaatagaa tgtaaagatt ttgtaaatta ccctgtactt
    13381 ttaataatat cataacaaac gaaaaataaa tagactatta aaaataatca ttttcatata
    13441 caataatatt aatttaaata caataaattt ataaaaattg tatttaaaga ttaacatatt
    13501 aaagtattag aattggaaag gcttgaaggg agaggttttt atgcaaataa tagtatctgg
    13561 gagacaaatg aaattaactg acggaataaa aggatacgta gatggaaaat taagtaggtt
    13621 agaaaaatac cttgatcctg aatcagaagt gaaagtaaca gtaagtgcga aaaaggatag
    13681 acaaaaagtg gaggttacaa taattcctat taacggtcaa ataataagag cagaagatgt
    13741 agaagatgac ttatatgcag caattgatat tgtttgtgac aaattaagta gacaagttgt
    13801 caaatataaa actaaagtta aagacaaagt tcaaaataat aagagcataa gatttgaaaa
    13861 tcttgacttt atagataata gcagtgaatt tgatgattat gattatgatg atgaagaaga
    13921 tgaaaatata gtaatagaaa gaagaaagaa atttaatgta aaacctatga gttctgagga
    13981 ggcgatactt caaatggaac tagtaggaca caatttctat atgtttagaa accaagataa
    14041 ttttgaaata aacatagtgt ataagcgtaa agctggtgga tatggtttaa tagaacaaga
    14101 ttaataaaaa ttgtatacgt ttagatttta tataagaaaa aataaaaagg taatcatgtt
    14161 gattttttat caatatgatt acctttttct tgtttaaata atatattaga tattaggtat
    14221 ttattatata aaaattttaa aactaatctg ttacaacatc aataaagtgc ataaatacct
    14281 atttcaagca taaaattaat taagggggta atgcttatgt tagaaatatc cactgattta
    14341 caagtaaatc aaccagttat tactgttaca agtaatacgt ttattagtat agaaaattat
    14401 ctatcaatat tagaatatga agttgattta ataagaataa agactaaagt taaaacaatt
    14461 aaaatatctg gggataaact ttcacttaag tatattactg atagtgagat aggtataaaa
    14521 gggattatct acaatgttga gtatgttgat taggaggaga tacacttgat aagttttata
    14581 aggggatact atgttatagt tgtggaagga gtaggactcg aacaattttt aaatcatctt
    14641 ataagaaatg ggataagtgt ttacaatgta actagaataa aaaatactaa aatggagttt
    14701 catatagata gacaagatat aaaagacttt aagaatgttt atagaggaag taagtttgat
    14761 ataaaggtaa agcaaaaaac tggggtccct tttattatca aaagagttta taagcacaaa
    14821 ggtatgtgga tttgtgctct tgtttcttta tttttattga tgtctacatc acagtttgtg
    14881 acagatgtat atatacaatc tcctgaaggt ataaaaaaag aagctcttag aaatgagctt
    14941 tataaggttg gagtaaggcc aggagtctat aagaagagta ttgatagaaa agaagttaga
    15001 gaccatatga tgtcaaaatt taatgatgtg gcatatttat ctatcaatgt aaaaggaaca
    15061 aatatatttg ttactgttac aaaaaaggca gaatccctaa aatctacaga ccaatcaaat
    15121 tattgtaatg taattgcttt aaaaaatggt ataatagaaa aggtaatccc tagaagtggt
    15181 aaatcagtta ttaaatctgg agacatagtc caaaagggag atgtcttatt aaatggagct
    15241 aataccaagt caataccaga agtatgggca agtacttttt atgagtccac aaaaaaggca
    15301 agttatgtag atactgtaaa taaaaaaact ggagaaaaga aaaatatata tacactaagt
    15361 ttttatgata aagagtttac aatgagaaaa aatataaaat ataaagatta tgttgttgaa
    15421 aataaagaaa aaaaactatc aataggaaac tatacttttc caataaagat aaaaacgagt
    15481 actttttatg aaacaaaaaa ggttgaagta aaaaggaata aagaagagtt aaaaaaagaa
    15541 ttatctgaaa aagctttaaa agagttagaa tacataatcc cagcttcggc tagaataata
    15601 gatgtaaaac ataactttaa ggttaataaa aatatgttag aatatttaat aacagttcaa
    15661 actagtgaaa atattgctaa aatttatcct cttagtaagt cagaagcaga aaggtttata
    15721 aaggaagaaa gtaaaccaga tgaaggtgaa gaggaagttc cttccaatcc agaaaaaaga
    15781 ccattaaatg atataagaaa tgagtttgat gaggataata aggataataa agaccaaaac
    15841 aattctgatg aaaataatag taatcaaaat agtaataata gtcaaaataa taatagcaat
    15901 aacaactaat aaaattaaac ttaaaatctt aggaggacta attcaattga taatacaaaa
    15961 gaaatttaca atagcagatg gtaactttga aagagagtta tttggcaact ttgatgaaaa
    16021 tgtaaaatta atagagaaga ctttaaatat agatgtaata cttagagaag gcaatataat
    16081 tttaattgga gaagaaaaaa atgtagattc tgcattaaaa cttatgaatg aattacacca
    16141 aactgtatca aatggtaagc atttagataa gcagagtatt tcttattcat tatctctttt
    16201 gcttgaagga agtgaacaaa aaataaaaga acttgagggg acaatcgtca taactcaaag
    16261 gggaaaagct gttcaaccta aaactttagg tcaaaaagaa tatataaaac ttatagaaaa
    16321 taatgatata acttttggtg ttggacctgc tggaacagga aagacttatc ttgcggttgc
    16381 tatggcagta aaagctttta aaagagatga agttagtaga attatactta caagaccagc
    16441 tgtggaagca ggagagagtc taggtttttt accaggagat ttaaaggaca aagttgaccc
    16501 atatttaaga ccactatatg atgccttatt tgaaatgttg ggtgctgata aatttaataa
    16561 gtatttagaa agaggtacta ttgaggttgc accacttgca tttatgagag gtagaacact
    16621 tgataattca tttataatat tggatgaagc tcaaaatact acttctgaac aaatgaaaat
    16681 gtttttaact agacttggat ttggctctaa agctgtagtt acaggagatg taactcaaac
    16741 agatttacca caaaataaga agagtggtct aatacaagct acagagattc ttaaaggtgt
    16801 tccaggtatt gggtctataa tgctaacaga tagagatgtt gtaagacatg agttggtaca
    16861 gagaataata agagcttatg agaagcacga caaaagagaa gaatttaaaa aagaagaacg
    16921 taaaaaagcg aaaatgcagg aaaagacttt caaaagaaag taaaagtgta gtaatataga
    16981 tatatagcat tattaatgaa taaaaagtag gtgtagtgaa tggatttgat actagatgat
    17041 agacaagata aattagaagt aagtgaggag ttaattgaaa agataaagga tataatcata
    17101 gaatgtttag attatgaagg atatgatgat aattatgaag tgagtctttc ttttgtagat
    17161 aataaagaga ttcatgaatt aaatagagaa tatagaggag ttgatagagt gactgatgtt
    17221 ttatcatttc ctcttttaag tgatgatttt gaagatgttg agttagaaga agaatcccta
    17281 ggtgacatag tagtatctct tgaaagagcc ttagaacaga gtatagagta taaccatagt
    17341 tttgaaagag aagtatgttt tttaatatgt catagtatgt ttcatctttt aggttatgac
    17401 cacgatacag atgaaaatac aaaagaaatg agagaaaaag aagaacacat attaaataag
    17461 ttaaacataa caagggagta gtttttatga aaccagaaaa aactcgtcaa ggtataatta
    17521 aagcatttaa tgcagctata gaagggatat tgtatacatt taaatttgaa agaaatatga
    17581 aaatacatta tttaggttca gttgctgttc ttataataag tttgtttttt aacttttcaa
    17641 aattagaaat gataatgtta cttatgtcca tatgtttagt tgtagttgct gaaatgttta
    17701 atacagctat agaaaaagct gttgatttag taactgatga atatcatgtt cttgctaaga
    17761 tagcaaaaga tgttgcagct ggaggcgttc tagtggcagc actaaattca gtagtagttg
    17821 gatatatttt gttttatgat aaattgacag atatatctgg aatattaatt tataaaataa
    17881 gagaatcaga attacatata accttgatat gtatattatt ggttcttata gctgttgtag
    17941 ttgtaaaagc attgacttct acaggtactc ctctaaaagg aggaatgcca agtggtcatg
    18001 ctgccttagc atttgctata gcaactgcaa ttacacttat gactgaaaga gttgttgcct
    18061 ctactcttgc atatataatg gctgtattag ttgcccaaag tagaattgaa ggaaaaatac
    18121 atacattttg ggagactatt gctggagctt tgttaggtgt gttgatagct atattagtat
    18181 ttcagcttgg aatgttctat aattaaaata aatgtacata aaatatttaa aataaaacaa
    18241 atctgtgcta attaaatttt tatgatataa tgtagagtat taaataaaaa taacttttaa
    18301 ttattgtata caggaggagt tgttgtggat aacatagaat tgttaaggtt ggcagaagat
    18361 gccagacaac attcttatgc tccttactca ggttttagag taggtgcagc tcttttaact
    18421 aagagtggta aagtttatac tggatgtaat atagaatgtg catcattagg tggaacaaat
    18481 tgtgcagaaa gaacagctat ttttaaagca atatcagagg gtgataagga tatctataaa
    18541 atagctatag caagtgataa ctcagaaaat aatgagcaaa catatccatg tggaatatgc
    18601 aggcaggtaa ttatagagtt tggttctgat ataaaaataa taacgggata tactaaagga
    18661 gaggtgtttg agcatagtat aaaggatttg ttgccaaact atttctctgg aaatgattta
    18721 aaataaattt aaaagtataa ataaatttaa gtaattaaaa caagaagata aaaagttagg
    18781 agacagttaa tgttcaaatc aggttttgtc agtatagtgg gtagaccaaa tgtaggaaaa
    18841 tctactttaa tgaataatgt agttggagaa aaaatagcta taatgagtga taagcctcaa
    18901 actacaagaa atacaataca agcagtatat acagatgaag aaatgcagat agtattctta
    18961 gatacaccag gtattcacaa accaaaaaat aaattaggtg aatttatggt aaaggcagca
    19021 acagaagctt ttaaaaatgt agatttaata ttatttgtag ttgatgattc taaaaaaata
    19081 ggtcctggag atagaaagat aatagaggat ttaagaagtg ttaagacacc aataatttta
    19141 gttgtaaaca aaatagacca actagaccaa aaagatgagc tatttgatat aatcaaaatg
    19201 tatgatagag aaggtatttt taaagaaata gtaccaatat cagcattaaa aggaaagaat
    19261 acggatacct taataaaagt tatacaaaat tatttagaag aagggccaaa gtattttcca
    19321 gattatatga ttacagacca gccagaaaga gtattaatag cagaacttat aagagaaaaa
    19381 gttcttcact atcttaatga tgaaatacct catggtgtag ctgttgaaat tgaaaaaatg
    19441 aaagcgagaa atgataagga aatagtagat gtatctgctg taatatactg tgaaagagat
    19501 tcacataagg gaataataat aggaaaaaat ggtaggaaac taaaaggaat aggtaagtca
    19561 gcaagacaag atatagaatt gcttttaggt tcacaaataa atcttcaatt atgggttaaa
    19621 gtcaaggaaa attggagaaa tttacaaaat tatataaata attttggata taatgataaa
    19681 taaaggtggg ttatatggat aggaaactgg atgcttccca agatttatta tatgaagtaa
    19741 aatcattaat tgataataat aaagtattgg agttaagaga attaatagag gaatatcata
    19801 taattgatat attcgatata atggaaaatt tagaggaaga catgaaaatt caattatttg
    19861 aagtacttcc tttagatatg gcatcttcta tattagaaga aggtagtgta gagtttttta
    19921 ttagtatttt atctaaactg gatgtagaac actcgaaaaa tatacttgaa cttatgtctc
    19981 ttggagatat ggcagacaag ttgagtgaac ttgaagaaga agaaagagaa cacataataa
    20041 atcttttgaa tcaagagaat gccgattatg taaaagagtt actattctat gatgaagatt
    20101 ctgctggtgg aacaatgacc actggatata tttctataaa taaagatatg acagctcttg
    20161 aggctataga ccatatgaga gaagaagctg aagaagctga aactatttat tatatatatg
    20221 tggttgatga tgaagaaaaa ctagttggag tattgtcatt aagagaatta ataatagcta
    20281 gagacgcaaa tatagtagaa gatttgatga gtgaaaatat aatctctgtt tatgtagatg
    20341 aagatagaga agaagcagta agattagtat ctaaatacaa tttaatagca attccagtag
    20401 tagacagaca agaaaaatta aaaggaataa taacagtaga tgatataatt gatgtaatgg
    20461 aagaagaagc aactgaagat atgtataaat ttgcaggaag ttcagaacat gaaagagaag
    20521 ttgcggaaaa agaaaaccct acattgagag agcaaataat atcagcactt agaggacgat
    20581 taccttggtt aattattacc ttagttggag ggttgttggc ttcgttaata ctttctaact
    20641 tagactatat aatgaatcct gtatatgctc cattagtatt ttttatacct gtagtaattg
    20701 gtatgggtgg aaatattgga actcaatcat catctgttac agtaataaca ttgtctaata
    20761 aggatttaaa ttttagcaat gtggttagag aaggtattgt aggtattatt acaggtcttt
    20821 tgtgtagtat aataacaggt attgtaattt actttgttat gagaaagtta gacattgtat
    20881 taattgtttc aatatcatta tttataaata tggttttagg tgcaacaata ggtgcgttta
    20941 tgcctgtttt attaaaaaaa atggatgcag acccatctac agtttcatca ccaattatat
    21001 ctacagctct tgatataact ggtatagcag tttactttat aataacaacg gcattattgt
    21061 caaaaattgt ttaataactt tatgtatgat ttatcctctt cttactaaaa atataagtat
    21121 aaatgtaaga agggggtttt ttaaaaatga acaatatcag ttgggaagtt tttaaaaaaa
    21181 caggtagtat agatgcatat ttatatttct gtgattgcaa aaacatacat gaagaaattg
    21241 aagaagtaag ggagaaaaaa gaagacgatg ataatcctga acacccaggg gatagtactt
    21301 aaagctataa ggtataagga aagtgatata atacttacac tatttacaag aaagcttgga
    21361 aaagtatctg caatagcaaa aggagctaaa aaaaataaga gctctttgct ttcatcatca
    21421 cagttatttt cttatagcaa ttttacctta aaaaaacaag gtaatatgta caaggttact
    21481 caaagtgaaa taataaaaag tttttataat atatcctatg atatagaggc attttcttat
    21541 gctacatata ttacaaaatt agttgaaaat tctatacttg aaaatcagac taataatagg
    21601 ctatttatat tacttgcgca gactctgtat ttgtatacac aggataatac agacaatagg
    21661 tttataacag cagcattcga gttaaaattt ttagactata taggatttaa acctatagta
    21721 aataaatgca ttaattgtga atgtaaaatt ttacaaaatt ctgtgtttaa tatctacgaa
    21781 ggtggtatac tatgtagtaa gtgtagtaaa ctttttgata ataatataaa attagactta
    21841 acaactataa gtcttatgga atatgtatta agaaatgata ttttaacatg tagtaaagct
    21901 aaagtatcaa aatatataac acatgaactt gagaatattc tagacaagta tttgaaagtt
    21961 tatgttgata atattaattt taaatcatta cacgtattgc aaagtgtaaa aaataataag
    22021 ggagtggata atgatgagta gtaatataac tattgaaatg gttgattcag tctttgaaag
    22081 agttccagga gcaacttatg cagaagcaaa agaagcatta gtaatgtgca atggagatgt
    22141 aattgaggca gtaatatatt tagaaaataa aaaaaatact tgtaattgta aagcaaaatc
    22201 tgctaaagaa actatggaag aagtatttgg caaagatgga gaaaatataa agtttcaatt
    22261 aaaagagctt cttagaaaaa gtagtgtagt gcgaataata gttgaaaaag atggaaaaac
    22321 tatgatgaac attcctttaa cagttggagt tgttggatta gcttttgtac cattagctac
    22381 tttagttgga ttatcagctg ctgttataag taaatatcgt ataaaagttc aaaatgaaga
    22441 agatggagaa attgtagatt taggtgaatt gaatgaagaa aaacttcacg ttttgaagaa
    22501 tatgataact aatgcagcaa aagatgtgaa ggatgtagta gttgacaaaa aagaagatga
    22561 caaagatgta actgctgacc ttatgaaaga agaatctgaa aagaataaag aagacgaaga
    22621 cgaaaataaa tagatataaa gtgactttta aaaaatgaag agaagataat tataagaatt
    22681 atcactaaca ttgacaaatt ttatagaatt tgatattcta aaagttgtag aagaactatt
    22741 aaaatagcct ttcgtgtaga cgagaggctt tattgttata ggagggattt ttatgaattt
    22801 tcaagagatg atactggcgt tgcaaaaata ctggtcaaag caaggttgta tcatgatgca
    22861 gccttatgat attgaaaaag gtgcaggaac tatgaatcct aatacttttt taagatcatt
    22921 aggacctgag ccttggcaag tatgctatgt agagccttca agaagaccag cagatggaag
    22981 atatggtgaa aacccaaaca gactatatca acatcatcaa ttccaagtta tactaaaacc
    23041 ttctccagat aatatacaag aattatattt ggaaagttta aaagagattg gaattgaccc
    23101 aagtgagcat gacataagat ttgttgaaga taactgggaa gctgctacag ttggtgcttg
    23161 gggacttgga tgggaagttt ggctagatgg tatggaaata actcaattta cgtattttca
    23221 acaagtaggt aatattgaat gtgagcttga gacaggagaa attacatatg gattagaaag
    23281 attagctatg tacattcaag aagttgatag tgtttatgat ttaaaatgga atgataaaat
    23341 aacttatggt gaagtattta ataaagctga gtatgaaaac tcaatgtacg catttgaatt
    23401 atgtgatgca gatatgttgt ttaatctgtt tgatatatat gaaaaagaag cattaagact
    23461 tatggaaaat ggccttgtaa taccttcata tgactatgtg ttaaaatgct ctcatgcatt
    23521 taatacattg gatgcaagag gtgcaatagg agttagtcaa agagcttcat ttataggtag
    23581 agttagaaat atggcaaaga ctgttgcaga aacttttgta aaacaaagag aagaaatggg
    23641 attccctctt ttaaaggacg gtgacaaata atgaaaaatt atcttttatt tgaaatcggt
    23701 gttgaagaaa tgccatcaag atttgtaggc agtacactag aacaattaaa aaacaatctt
    23761 agtaaattat ttgatgaaaa tagaatagct tttgataaaa taaatgcgta tgggacacca
    23821 agaagactta ctttagtagt cgaaggattg agtgatagac aaaatgattt agaagaggaa
    23881 ataaagggtc ctgctaagaa aattgctgtt gatgcagaaa ataatttaac aaaaccagca
    23941 ttaggattta taaaaagcaa aggattaagc gaatctgaca tatattttaa acaagttgga
    24001 aaagaagaat atatatttgc gactataaag caagatggaa aagaaacttc agaagtacta
    24061 aaagacatat taccagagac tataaaatct gtagtattcc caaaagctat gcgttgggga
    24121 ggaaaaaatc ttaaatttgc aagacctata agatggatag ttgcattgtt aaatgataaa
    24181 gtattagagt ttgatttaga aggaataata tcttctaatg taacaaaagg tcatagattt
    24241 ttaggtgaaa gtacaataga agttgattct atagaagatt attttgaaaa attagaaaaa
    24301 aattatatag ttttagacca aaacaagaga aaagaaatga taagaaaaca atgtatagaa
    24361 gtggcaaatt ctttaggtgg agaagttgaa tttgatgaag atttacttga agaggtaact
    24421 tacttagttg aatatccaac tgctttttat ggagaatttg atgtggatta tataaaacta
    24481 ccaaaagaag ttgttataac tcctatgaaa caacatcaaa gatattttcc agtacttaaa
    24541 gaaggaaaac tgttacctaa ctttatagct gttagaaatg gtgattctta cagaatagac
    24601 aatgttaaag ctggaaatga aaaagtttta gaagcaagac ttgcagatgc tttatttttc
    24661 tatagagaag atactaagag aaacttagaa agctacatag aaaaattaaa aactgttgta
    24721 ttccaagtaa aactaggaac tatttacgac aaaactttaa gacttgaaaa attaagtgct
    24781 gatatacttg atagtttagg tttagtagat gaaaaggcag atactataag ggctgctaaa
    24841 ttatctaagg cagatttagt tactggaatg gtaggagaat ttgatgaatt acaaggtttt
    24901 atgggaaaag aatacgcaaa agttggagga gaaaatgatg ttgtaagtga agctattttt
    24961 gaacattatc ttccaagatt tgcaggagat atacttccta agactaatgc aggagttgcc
    25021 ttatcaatag ctgataagtt ggattcaata gcaggtttct ttgctatagg aatacaacca
    25081 acaggttctc aagacccata tgctttaaga agacaagctt taggtatact tagtatactt
    25141 atggacagaa aagttgctgt ggatataaaa gtacttattg aacatgcttt agacaattat
    25201 tctgaattag attttaataa agaagaagtt gttgagcaaa taatgaattt cttcaatgag
    25261 agagtaaaaa atctatttaa agatttagga ataagatatg atgttgttga tgctgtttta
    25321 agttctgata taaatgatgt ttctgatatg catatgagag ctttagagct taataattgg
    25381 ctagaaaaag atgaattagt ggagatgctt actgcattta atagagtttc tactctagct
    25441 caaaaagcag aaagtgataa aattgatgaa tctttattaa aagaagatgc tgaaattaaa
    25501 ctttacaatg aatttaaaca agtaaaggta aaagttaatg aattattaaa ggataagaaa
    25561 tatggtattg ctttagatga atttgcatct ttaagaccag tagttgataa tttatttgat
    25621 acagttatgg ttatggataa tgatgaagct attaagaaca atagacttgc tttacttaaa
    25681 caagtatatg atactatgct aggaatttgt gatttatcta aaattgttta taaataaaat
    25741 ttaaactatt tataagaaat aaggctgtct caaaatagag atagtcttat ttttcattgt
    25801 tgagatgatg aaaatatatt tgatttcata gaaaaagagt gtctcataaa ctaaaaagtt
    25861 cattttgaga cacccatgct ttttgtaagt aaatataata aattatattt tatacttatc
    25921 agttattttg tttaaaatat tatcatttga atttacccat tcataaaaat tgcctgatga
    25981 tgcgtccgat attttataaa gcatttcagg aatatcacta gctttaaaat ctccaagtga
    26041 ttttcccaat ctagtcttac ctatttcaaa actgcctcca acaaataatt caaatgcatc
    26101 tgtagatata ccatcaacat tcttcttttt accacataaa cctatgctac caacttgatg
    26161 aacaccacat gaatttaaac atcctgatat atataactta ggtgctttat ttaaaatttc
    26221 tttattattt tgtaatctaa aataatctat gatttcatgt aacattttct gactattttg
    26281 tatgcccatt tgacaaattg gaacacctat gcaagatata ctttgttcta attgagaatt
    26341 acaactaata gttttactta tttctaatat tctttttgct tcatttccat ttaaatttaa
    26401 aatatataat ccctctgtca ttcctagtct aatcatagga ttttcaatat tatctaattc
    26461 tttaagtaaa gtacttaaat cctttgttaa caaaatacct ccaactggat gtatatatac
    26521 agtgtataaa ccatcctgtt tttgaggtat tagtctagaa tcctgtatat ctattttaac
    26581 cccaggttta gagtaatcta tttcttcaat attgagttca agactaccat tttctttttc
    26641 taatttatag tattctttaa atttttctaa gaataatttt tcaccaagtg attcgaccat
    26701 atatctaacc ctagctctgt ttttattttc ataatttcca taatccataa agaatttaat
    26761 cataccttca acacaatata aggcatcttt cggttttata agttcatcaa gttctaaagc
    26821 aactttgggt tgtttaccta gacctccacc taagaaaact ctgaaatatg gttcatcatt
    26881 tttcaaagta gcaacaaatc ctaagtcttg tatactacaa tgagcagtat ctgtgtaaca
    26941 attagaataa gaaactttta attttctagg taaatggtat gtagtagcat ttttgataaa
    27001 atatttatca gtagcaactg catatggagt aacatcaaag acttcactag ggtcaactcc
    27061 agataatgga gataatccga catttctagg ataattacca ccaccacctc tagtgaatat
    27121 atcatttttt attccttctt ccatgatatc aacaattgaa tttatagata aatcgtgtaa
    27181 ttgtatagct tgtctagttg ttaagtgtat cttatctaag ttgtgtttaa tagctatttc
    27241 atagatttta ttaagttgat actgagataa aactccagca gatactctaa gtcttatcat
    27301 aaaagatttt ttgtctcttt gagcataaac accatatcca ccagaaaatc ccttatattg
    27361 cattttattt atttctccat ttaaaaattt tgaagaatat tctttaaaat taggtagttc
    27421 atttaacaat atctttttaa aattatccat tatttcacct cattgttagt cttgtataaa
    27481 aatatatcta ttgtataata gatatatata ttattatcta gtcaggataa aaatataaca
    27541 gaataattct attaaaagta agaataataa ggacatagtg agtattttgt ttttatttta
    27601 caaattaagt ataatatttt tgttttataa aatataatta agataaatag ataattttgt
    27661 aattttaata tataatattt agtagagtgt gggagtagca cttaatattt gaaggaggag
    27721 tttttgtata tgggagaaat aataaatgca ttagatagag ccctagacat aattttgctg
    27781 ttatatcatg aaaagagaga aatgggaata actgaaataa gcaaggctat gggagtatat
    27841 aaaagtactg tacatagaac tttggttact cttgaaaaca aaggttttgt tatacaaaat
    27901 gcagagaatg gtaagtattg gctaggaata aatttatatg caataggtat ggttgtggga
    27961 gaaaaaatgt cattgactga aatagtaaaa ccatatacga aaaaattaaa tcaagaattt
    28021 aacgaagtag ttaatgtatc tatattagaa gaaagagctc aagattctcc aagaagtatc
    28081 ataatacata aagagtatgg ttcaaatcaa ttactttcag taaatccatc cgttggttca
    28141 agtagtgaat gttattgttc agcagttggt aaatgtctta tggcatttaa tgattctata
    28201 gattttgaaa aatatagaaa aacaccaata cacaagtata cagaacatac aattgataat
    28261 tgggatgata tgatgctttt tttagcaaaa ataaaagaac aaggatatgc tatagatgat
    28321 gaagaactag aacatggact aacttgtatt ggagcaccta tcttagataa aaataataaa
    28381 gctattgcag ccataagttt gtcaggtcca actataagaa tgagagaagg ggactttgag
    28441 tataagatta aaagagttat agaaactgca aaaagtatat ctgaactttt tagatgattt
    28501 ttaatctcga taataaaaat aggctatatt taaattgtta tttgtaaata tcagtttaaa
    28561 tgtagcctat ttttctttaa tctaaaatta aatattctta aaatttaaaa tgttattgaa
    28621 atatataagc gaatgtgtta tcttttaatt aagcaataaa aatagaacaa ggttctatat
    28681 tatagaacaa aattgatgca tatatagtat ttatacaaaa tataaatatt atatatttaa
    28741 aattaagtaa aaatattaca taaaggggag atttgagaaa tggaaaaagt caagttgagt
    28801 gttgaaagat gtaagggatg ctatctttgt attgaagctt gtaaaaaaga tgcaataagt
    28861 ctttctgact acacaaataa aaaaggcttt gtaactatta aagtcgatga agaaaaatgt
    28921 attcaatgtg gcgcttgtta tacaatgtgc cctgatttag tatttgagat attataaatt
    28981 atttttatta gaggggagaa aaggtatgca aagtttatta attaaaggaa atgaagcttt
    29041 agcagaaggt gctatacgtg gtggctgcag attttatgca ggttatccaa taacgccaca
    29101 atcagaaata ttagaaatga tggcatggag acaaaaagaa gttggaggag tatttatcca
    29161 aggtgaatca gaaatagcca gtgtaaatat ggttatggga gcaagtgcac ttggagcaag
    29221 agctatgact tcttcatctg gtccaggatt ttcattaaaa caagaaggta ttgcatattg
    29281 ggtatcagct ggtttgccag cagttgtagc atgtgtgcaa agatatggta taggtgatgg
    29341 atttatagga gctggtcaag ataattattg gcaagcagta aaaggcggtg gaaatggaga
    29401 ttatcattta atcgtgttag cacctaatag tgttcaagaa aatatggata tggcatatga
    29461 atcttttgaa ttggctgaaa aatatatgca tccagtactt atactttctg atgctacaat
    29521 aggtcaaatg gtagaacctt gtatagcacc accaatgaaa gaatacgata tggataaagc
    29581 tccatgggct gcaaaaggaa cacctgtagg agaaaaaaat aaagtaataa ctgatataac
    29641 atattttgaa gaccaagata catggcaaaa agggtatata gaaaaaatga gaaaagttca
    29701 agaagatgaa caaagatggg aagagataga aatagaagat gctgaagtgg tatttgtggc
    29761 atacggtatt tcatcaagaa tagcagaagg tgcagttaga gatgctagag caaaaggaat
    29821 gaaattaggt ctaataagac caaaaacatt gtggccttac ccaagaaaag catttaagaa
    29881 attaagtgat tcattgaagg gacttgtaac agttgaaatg aacatgatgg cacagatgaa
    29941 ggaagatgta attatagcat gtgataatag atttccagta tattcagtag caacagctca
    30001 atatatggca gaagtaaatc aattaataga ttttgctcaa cagattatag atggaaaagc
    30061 taagcaagag gaggtatttt aattatggct aaaaaagcac cagcaataat gatgtgtgaa
    30121 aatatgttct gtggaggctg tggacactct atagtcgata gaattattgg agaagtatta
    30181 acagaaatgg atatatgtca agatacaatt atatgttcag atataggttg taatcatatg
    30241 tttcaattta gtatgaatgt agatgttgtc gttccacctc atggtaaaat gggagcagca
    30301 atggcagcta tgaaaagagt tagaccagat aaatatatat ttacaatagc tggagatggt
    30361 ggagcttatg caatagggct tggagaaact atgtcagctg ctactagaaa tgataatgta
    30421 atatttcttg ttatgaacaa taatatgttt gcaatgacag gagggcaaat ggctccaact
    30481 actatagaag gtcaatatac agcttctact ccagcgggta gaaattacgc agatcatggt
    30541 tcaacatttg atgttgtaaa agttatggga aatttagata tagcatatct agcaagagga
    30601 acaataacta accctaaaga aataaataca acaaaaagat acatcaaaaa agctctagaa
    30661 aaacaaaaag aaaagaaagg tttttgctta atagaagtgc ttgtaccatg tccaacaaac
    30721 tggggattaa agccagtaga tgctatgaag agaattgaaa atgaacttgt tccaaagtat
    30781 ccacttggag aatttattga ttagggagga aataatatgt tgaatgaaat tatatgtgct
    30841 ggttttggag gacagggagt tcttacagca ggaaaaatta taatgtatgt tgcatataag
    30901 gcagaaaaga aaattacatg gttcccatct tatggaaatg agatgagggg aggaagtgca
    30961 aattgcaatg ttgttgtaag tgatgaaaaa attgcaaatc cttgtgtaaa aaatccagat
    31021 atactattgg gaatgaacag cgtatcagta gataagtatg aaagtttaat gaaaaaaaat
    31081 ggttatatgt ttgtcaatga atcactagta agtaaggata gaaagtacag agaagacatt
    31141 aatgttataa aagtacctgt tactgaaata gcacaaaatt taggcaatga aaaagctgct
    31201 aacatttgca tgttaggtgc tatggtaaag agtttggatt tatttacaaa agaagaattt
    31261 gaaagtggta tgtgtgaata ctttgaaaat caaggcaaag gtaaattcaa ttctaaaaat
    31321 gtagaagcat ttgaagctgg atacgactac gaatgaatat tttaaatatt taaaataatt
    31381 attgaaatac ttatttttat atgttagtat ttaattaata aaatatagaa cgtcgttctg
    31441 gacaatggga cgaagtcttt aggtcggaat acaagaacgg cgttctgtat aatagaacta
    31501 gggggtgtta aattgaaagt tttagtaata aatcctggtg gtacatccac aaaaatttct
    31561 gttttccaag atgaaaatga aattttgaaa aaaaatataa cccatacaag agaagattta
    31621 aaaaattttt ctaaagtatt tgatgaatat gattatagaa aacaactgat agtagatatt
    31681 ttaagtagtg agaatcatag tataaattct tttgacgcag tagttggtcg tggtggactt
    31741 atgaaggcta taaaaggtgg tacctatact gtgagtgaag aaatgattga ggatatgaga
    31801 aatgaaataa atggggaaca tgcatcaaat ttaggtgcat tattagctaa aactatagct
    31861 gatgaaatag gagtacaatc atttgtagta gacccagttt ctgtagatga atttgatgat
    31921 gtatcgagga ttacaggaat atcagacata gaaaaagcaa gttggttaca tgcattaaac
    31981 cataaagctg tttcaagaaa aattgcacaa aaactagggg gaaaatacga ggattataac
    32041 tttattgtag ctcatttagg ttcaggaata tcgattgtag cacataaaca aggcaaaatg
    32101 attgatggaa gtggtggtag gtctgatggt ccattttctc cagaaaggag tggtggatta
    32161 cttgcatatc ctcttataga attgtgttac tccggaaaat atactcatga tgaaatggtc
    32221 gcaaaagtaa gttcgattgg gggaatgtac gattatttag gaacaaagga catgatagaa
    32281 attgaaaaca gaatcaagga gggtgatgaa aaggcaaaac ttataatgga tgcatttatt
    32341 tatcaagtag caaaagaaat ttctatgtat ggagcttcac tttcagggaa tgtagataga
    32401 gttatcttga caggagggat atctcactca gaaatggtag tcaaaggagt agcagaaaaa
    32461 gtttcatatc tagctccaat agagatagta ccaggagaga tggaaatgga ggcacttgct
    32521 ctaggggcac ttagagtact taatggagaa gaaatagcaa aaacttatta atatttagga
    32581 gaaagagtat gttaaaagat tttaataatt tattagaaga ggctaaaaag cttgaacctg
    32641 ttattgtaag tgttgctgtt gcagaagaca aagaagtatt aaaggctgtg aaatcagcaa
    32701 cagatttaaa cattataaag ccaattcttg taggagacaa ggataaaata gaaagtatat
    32761 caagagaaat tggattaaaa ggtcatgaaa taataggttg tcaaaatccc gatgaatcag
    32821 ttaaaaaagc tgtagagata gttaaaaata aggaagctaa agttcttatg aagggattag
    32881 taaatacaag tgtctatatg agagctatat taaataaaga aacgggtctt agaacaggaa
    32941 gattattaag tttgcttgca gtatatgaat tacctcaata tcataaactt ctttattgta
    33001 ctgatagtgg aataaatgta tcgccaaact taaatcaaaa aaaagatata atgacaaatg
    33061 cacttcttac tatgaaaagt ataggcatgg aaaatcctaa aactgcgata cttactgcaa
    33121 atgaaatggt agaccctaag atacaatcta cagtggatgc caacctactt gtagagatgg
    33181 aaaaatcggg agaaatacca aagtgtatag tggaaggtcc aatagcattt gatgtagcat
    33241 ttgatgcaca tgcagcagaa cataaaggta ttaaaagtaa tattgctggt gatgttgatt
    33301 tattagtatt tccaaatata gaagcaggga atatattagg aaagtcatgg cttagattta
    33361 ataaagctaa gtgggcaggt atagttttag gagcaacaaa tccgataatt ttaggttcac
    33421 gttctgacac agctgaaata aaaataaatt caatagcatt agcgtgccta gcatcacaat
    33481 aagaaattat tattaaggag gaaaaagtat tatgaaatat gcaaaaagaa tggatatggt
    33541 aaaagcttca gctataagag attctcaaaa gaaaatagct cagaaggtag caagtggtgg
    33601 aactgttata tcttttgctg cagggcttcc tgacccaaat ttatttccaa tagaagagat
    33661 aagtgaaata actcaaaaag tacttaatga aaggggaaaa tttgccctag catatggacc
    33721 tactaaaggt gaagatgagt tgttagatct attagtaaaa agaatgaaag aagaagaaaa
    33781 tattgataca aaagcagaaa atattataat aactactggg tcacaacaag ggatagcatt
    33841 aagtgctatg attttattag aaaagggaga tgtagtagtt acagaaaatc caagttactt
    33901 aggtgcaata aatgcattta gaccttatga atgtgatttt ttaggagtag atacagatga
    33961 agaaggaatg gtaacagatg atttagacaa attattatct gaaaattcta acataaaggt
    34021 gatatatgta ataccaacat ttcaaaaccc tacaggaaaa acatggtctt tacaaagaag
    34081 aaaagatttt atggaagtcg tgaataaata tgatgtcata gtaatagagg ataatcctta
    34141 tggagaaata agatttacac cagaacctct acctacactt aaatctcttg atactaaaga
    34201 taaagtattg taccttgggt cattttcaaa ggtattatgt ccaggattta gagttgcttg
    34261 gatgtgtggt aatgtagaca tcatagataa ggcagaactt ttaaaacaag gtatagattt
    34321 acagtcaaat caattttcgc aagtacaagt aatagaattt ttaaagaaat acaacttaaa
    34381 tgaacatata gaaaaaataa gagcagagta taagaaaaga tgtctgctaa tgttagatgc
    34441 tatgaagaaa catttcccag aggaagctaa atatacagaa ccagatggag gaatgtttat
    34501 atgggttgaa cttcctgaaa gtataaatgt agatgattta ttagataaag ccattgatgc
    34561 tggagttgct tatgtttctg gagagtcctt ctttgcaaat aatggtccaa aaaatactat
    34621 gagacttaac tatacaacaa tgtcagaaga acaaatcgtt aaaggtgttg agatacttgc
    34681 agaagttata aaaaaagaac tcaattatgc ttgtgaataa atataaaaag tgagggttta
    34741 aatatgggag aaaaagaaaa cggtataaag tttggaaagt taatgtttca acttgttatt
    34801 atagcaatat cttgggaatt agtttatatt ataccattta tccaatatac attatatgat
    34861 ccaatcctaa aagcattaga atgtacaaac actcaactag gttttctact tacaatttat
    34921 gggttaggta atatatttgg agctcctata ggaggctggt tagcagatag atttgattat
    34981 agaaagataa ttttaggttc tgtatttctt aatggagtag tatcattttt atttgcattt
    35041 aatatgaact atccatttgc agttgctact tgggtaggtt gtgcaatcac atcattagtt
    35101 atgaactatc cttctatggt aaaaatactt agagttatag gaaaagataa tcaaggtaag
    35161 gtttatggat ttaatgaagc tatggttgga gtttctggag tagtaatggg agcaatattc
    35221 ttatatattt atacatgctt tgcaactcct acattgggta tgagatgggt aatgatatct
    35281 ttaggaatat tatcaatagc aatgtgtcca gtattatggt ttgtaattaa agatgtagat
    35341 attaaagaag aaagagaaga agcaggtgaa aaaatgtctg ctggtgattt tataacagta
    35401 ctaaaatcac caaatacttg gctagtagga ataagtatat tctgtgtata ttcattcaca
    35461 gttacaatgt cttattttac accatatata acatctgtac ttggaggttc tgtagcatta
    35521 tctggtgcat tagcaataat aagacagcat ggtctaaaat tatttggagc accatttgga
    35581 ggatattgtg cagacaaatt aaaatctcct acaaaagtac ttttaccaat atatgtattt
    35641 ggtatagcag taatagtttt attcctagta ttacctgcat caactccaat gactatattc
    35701 atagctttaa catttgtagt aggtatatta ggttacatgg gaaaaggtat atattatgca
    35761 gtacaagatg aagtaaaagt tccagttaaa tattcagcaa ctactatagg tatagctgca
    35821 gctttaggat tttcaccaga tgtattccaa tttgcattaa taggacactg gatagatact
    35881 tatggcaata aaggttacac atatacattt atattccaaa tagcaattct agttattgga
    35941 atactatctt gtttatatat attaaaggtt aaaaagagaa gagcaagtaa attagaagct
    36001 taaatattca atttggtaat taagtatata taaatacaat acttattttg atgaatgtga
    36061 ttgtataaat aacataaaaa atatcaatag attaagtttt ataataatgt ttagagaata
    36121 aagtataaaa atcaaaatgt tatcaagttt tctaggtttt aacataaagt tacccctgaa
    36181 ggtgtaaaat tgagtggcaa ttattatcta ttttcttacc tacataaacc tatttaattt
    36241 aaattctaag agattttcaa aatagatggt agttgtactc aattttaaac ctcataataa
    36301 atacgaaaat ttaaaatcta actagatact atttaattat atattaataa atatatattg
    36361 tactatttat ataataataa tttcaggctt ttcattatat gtattccaat ttatattgtt
    36421 tgattattat tcaaacacac gtcgttaaaa attttataaa tttatgttta gatatgatta
    36481 atactcttga ttttagaaat aaatatttgt agattgtaga ttaaagataa tataaataaa
    36541 tagaaggtag attttttaga tatattaata taaagattat ataaaatatt gaaatatagc
    36601 tgtttaaatt attgtctata aatataaaat gaatggtggt gagttaagtg accgatttag
    36661 ttaacaccat taatggaatt gtttggtcac ccgtattagt tgcaatgtgt ttgtgtatag
    36721 gattatattt ttcattgaaa ttaaaatttt ttcaaataag agatgtaaaa gaaatgttta
    36781 ctctcttgct tgagggagat agttctcatg ttggtatatc atcatttcaa ggttttgcta
    36841 catctatggc tggaagaata gggactggaa atatagctgg tgtagctgta gcaatagcaa
    36901 tgggaggtcc aggagcatta gtatggatgt gtataatggc tacattaggt tcagcaactg
    36961 catttgtaga atctacttta gctcaaatat ataaagatga gcatgatggg cagtatagag
    37021 gaggacctcc atattatttt gaaaaaggtc ttgggtggaa aaagtgttca gttttatttt
    37081 caatagttgc aataataagt tatacatttt ttatgcctgg tacacaatca aacactttat
    37141 atctagcaat gaatcaagca tttggatttt caaaaatgac aatagcagta gcatcttcta
    37201 ttgcattagc gataataatt tttggaggaa ttaaaaggat tggtttattt gctgaaaaag
    37261 tagtacctat aatgggtgga gcatacctta ttatgacatt agtaataatt ataacaaata
    37321 ttagtttagt tccagaggct attgtaacaa tgtttaaatc tgcatttgga tttggttcag
    37381 tttttggagg aatgctaggt tcagcaatat cttggggagt aaaaagaggt atatactcaa
    37441 atgaagcagg agaaggttct gggacttatg gtgcggcagc agcagaagta agtcatccag
    37501 ccaaacaagg attagttcaa gcattttctg tttatgtaga cacattatta atatgtatgg
    37561 ctacaggtat tatgattgta ataacaggaa tgtataatgt tacaggtgtt tgcacagcac
    37621 taccaggtgt agaaccggga ccacaatatg tacagagtgc aataaataca ttacatccac
    37681 aattaggtga tatttttata gcaatagttt tattattatt tacatttaca actttattag
    37741 ccttctcata tatgatggag actaatgtat cttacttagt aactagaatt aaagcagaaa
    37801 aacatgaaaa gtacataatt aatgtctgta gatttatgct tatagcatgt gcagcaatgt
    37861 gttgttttat agaaccactt acaagctggg cattaggtga tatatgtata ggtgtattaa
    37921 catatataaa tttaattgcc atctttacac taaaaaaacc agctataaag gcatattatg
    37981 attatataag acagaagaag atgggaataa aaaggagtga tagaactttt aaccctatag
    38041 agttagatat aagaaatgct gagttttggg aaaatagata cttaaaagag gataagcatg
    38101 agttaaatta aagttataat aaaatataaa aattactaaa taaatttagt gggaggtaag
    38161 attggtatga aagaaagaat aatacaagtg gctgattcaa agaaagaaaa aattctaggg
    38221 ctatgtcaat ctttatatga tgaaccagaa attgctttgc aagaatataa atctgctaaa
    38281 aaaatatcag aatttctaag agaagagggt tttgatgttg aggaaaactt ggcaggtatg
    38341 gctacagctt ttaaagcaac caagaaaaat ggagatggtc ctaaaatagc atttatagca
    38401 gaatatgatg ctcttccagg caatggacat gcatgtggac atcatttaat tgcatctatg
    38461 ggagttggag ctggaatagc tctttcaagt atactggata cttacaaggg agaagtaagt
    38521 ataattggaa cacctgctga agaaactgga gatggaaagc cttacttgat agaacatggt
    38581 gtatttgatg gctatgatgc agcaatgatg atacatccaa attcaaaaac ttgtgtaaca
    38641 cctgaaatta tagcaatagg aggtctagat ttcatattta ctggaaaagc atctcatgca
    38701 ggagctaagc catataacgg aataaatgct ttagatgcag tagtactact atataataat
    38761 ataaatgcac taagacaaca attagtagat ggaacgagaa tacatggtat tatattagaa
    38821 gcaggaactg ctgcaaatgt aatacctgat atgggaaaag taagattaga gataagggca
    38881 aaagaacaaa attactttga tgaagtagta gaaaaagtga aaaattgtgc tagaggtgct
    38941 gcaatagcca ctggatgtga acttgaattt tatcactttg aaccaacttg ccaaggatta
    39001 aatgaaaata aagttttggt agacatattt acaaagatta tggaggaatt tggaatatat
    39061 gaagatgaac aagtaatgtt aggttcaaca gatatgggaa atttaagtca aataatgcca
    39121 tgtatacatc ctttgatgaa gttttctgaa aatggagaag aactacatac aaaagaattt
    39181 ttggaggctt ctataaattc atatgcaaaa gatagagtaa ttgatggtat aaaaatatta
    39241 gctttaacag gatttaattt atttgaaaat ccagaattat tgaaaaaaat gaaggaagag
    39301 tagaacttag actattttta attatactct ttaaaataag aagagtgtct caaaatgaac
    39361 tttttagttt atgagacact cttttttgta tgaaattaaa tatattttta ttattttaaa
    39421 catgaaaaag aggcttatct gtttttatat gacctttttt aacttgtagc acaaaatatc
    39481 atgaatgatt acaattcgaa tgataaaatc gattataaga tatataggag gggtacatat
    39541 ggaaacttta gaagtaagaa atattgaatt gagtggtaca aattatgaga taggatacag
    39601 actaggagaa ttggttgcta atatgccaga gataatagaa ggtcagatta ataaatctaa
    39661 tctggtaagc aaaaaagaag aaaaagagat gatagagttg tttgataaat attgtccagg
    39721 tcttaatgaa gaattgcaag gttttgctga tgcaattcaa gtgaattgta atcaaatttt
    39781 atattatact atgacttatc ttaaaccagg ttgtagtcaa gttgcattag caccagaatt
    39841 aactgaaaat gggcatgtac tatttgcacg taatttcgat ttctcacaca atatggagga
    39901 ttttgtttta tgtaaaacta aggtaaatgg aaaatatgca catataggta ctaccattat
    39961 gcaatttgga agaggtgaag gtatgaatga atgtggctta ggtgtaagtc agtcatcatg
    40021 tggtattcct gtaggcaatt cagatggttt aagaaaacca gcaattgtag gtttacagtt
    40081 ttgggctgtt attagatatt tgttagaaaa ttgcaaagat gtagatgaag cattagaata
    40141 tttaaaagat atgccaattg catacaatat taatttattg cttgcagata agtctggaaa
    40201 cattgcactt gtggagactt tagatgggaa aaaagaagta aatataatca acagtttaga
    40261 aagtaaaaga gaatattttt tacactctac taatcataca catattgata aacttcataa
    40321 attagatcca caatcaatga aaaattctat tcatagatat aaattaatta aagaatatat
    40381 aaataagtct aaaaaaattg gagagaaaga gttaatgaat ttattgtctt caaaatatcc
    40441 aaatggctta tcttgtaatt actataatga tttttttgga actttaaaaa gtatagttat
    40501 ggatttaaat ataggaaagt ttaatatttt atggggtgga ctagagaata aatgggagag
    40561 ctactattta aaaaatgaca ttaaatctat aacacagagg ataaacataa atattgaaaa
    40621 agcaccatct gacttttttg atttcattga ataaaaaatg tatttaatta ttctaaataa
    40681 ttaggacata taaatcaact aaaagttttt atttatcgta ttgaattagt tataatattt
    40741 tagtatagta aaaaatagtg ctattttaca tatttaaaga gtttaagtag aagagaggtg
    40801 ccatattgga ttacttaaag tattttgaaa aagctgtaat gtatattgag aataatttac
    40861 atgaaaatat aactgtaaat gatgtggcaa aagaaactgg atattcttat tatcatttaa
    40921 cacgcttatt taagtctatg tttggtgaaa gtgtaggaag ttatataaaa aaaagacgat
    40981 tagtaagtag tacaaaagaa cttttatata gtgataaaaa agtgatagat atagctattg
    41041 gtagtggatt tgaatcttca gaagcattta gcagagcatt taaatctata tacaaggtta
    41101 gccctataga atatagaaaa aatagaattg atgtatttgt tggtaaaaag aaaaaattag
    41161 agttagattt tatgagacat cttgttggaa atataacgat taaaccagtt ataaaagaaa
    41221 tagaaaaaat aaaggtaata ggtataaagg ataaagtaat tttagaaaat aattcattac
    41281 ctgacttgtg ggagaaattc agaaaagtac atcatattgt cccaaatact ttgccatcaa
    41341 ggagagtttt tggaatctgt gaagcaatct ctgaaataca cctagttagt gaaagtatgg
    41401 agtttaatga gataatagga cttgaagtta atagttatga tgtgattcca aattcatttg
    41461 tttcaaaaac tattaaggaa ggaaagtatg ctatatttac tcatactggt agcttagata
    41521 atttagacaa aacttatgaa tatatatggg gtacttggtt tttaagttca aaagaagaac
    41581 ttgatataag agatgatttt gaagtatatg atgaacgatt tttaggtcct agtaatgtga
    41641 actcacaaat tgatatttat atacctataa aataatctat aagaaaacta aaagataatt
    41701 tgattaagaa atagatgttc gtaaaagagc atctattttt tatttttata agatttagat
    41761 aattttaata ataaaagaaa taa
//
LOCUS       DAYAOO010000031        40816 bp    DNA     linear   BCT 12-OCT-2024
DEFINITION  TPA_asm: Clostridioides difficile isolate ST8-SSI-h139-18
            SAMN40601845-rid21577343.denovo.031, whole genome shotgun sequence.
ACCESSION   DAYAOO010000031 DAYAOO010000000
VERSION     DAYAOO010000031.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN40601845
            Sequence Read Archive: SRR28438827
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 40816)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 40816)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-MAY-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-MAY-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002157583.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002157583.1
            Genome Coverage       :: 163x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/11/2024 16:19:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 4,038
            CDSs (total)                      :: 3,963
            Genes (coding)                    :: 3,930
            CDSs (with protein)               :: 3,930
            Genes (RNA)                       :: 75
            rRNAs                             :: 6, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 60
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 33
            CDSs (without protein)            :: 33
            Pseudo Genes (ambiguous residues) :: 0 of 33
            Pseudo Genes (frameshifted)       :: 7 of 33
            Pseudo Genes (incomplete)         :: 25 of 33
            Pseudo Genes (internal stop)      :: 11 of 33
            Pseudo Genes (multiple problems)  :: 8 of 33
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..40816
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN40601845-rid21577343.denovo.031"
                     /isolate="ST8-SSI-h139-18"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Denmark"
                     /collection_date="2018"
                     /collected_by="Statens Serum Institute"
     gene            155..976
                     /locus_tag="ACGI5H_001801"
     CDS             155..976
                     /locus_tag="ACGI5H_001801"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430437.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HFG9697508.1"
                     /translation="MIKKEISNFRGSSDYVVSPELMASVNVAIALEKPLLIKGEPGTG
                     KTMLAQAISNELKKDLVIWNIKSTTKAQEGLYVYDTVQRLYDSQFGGEGVDDISKYIK
                     YGKLGEAFSSNQQVILLIDEIDKADLEFPNDLLWELDKMEFYINETKETVRAKQRPIV
                     IITSNAEKELPDAFLRRCIFHYIEFPDRDMMEEIVKVHFDKVEEHLLEQVMTTFYWIR
                     SLKDIQKKPSTSELIDWIQALTLSGMPIEKIEKEVPFAGILLKNNEDIESMQRHL"
     gene            997..2193
                     /locus_tag="ACGI5H_001802"
     CDS             997..2193
                     /locus_tag="ACGI5H_001802"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861504.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VWA domain-containing protein"
                     /protein_id="HFG9697509.1"
                     /translation="MFIEFFYLLRSRGLNVSLNEWMTLIEALDKGLCYSNFSNFYYLC
                     RMILIKSESDFDKFDAVFLEYFKGIEHQEEIPEEIMNWLKKPDIDLEEFERLEQNPNI
                     NLDKLRAKLEERIKEQDSPHNGGNYWIGTGGTSELGHSGKGQTGIRIGGNSTYGRAVL
                     EVAGERKYRDFRDDEVLNMRQFQVALKRLRQFSTRIDAPKTELDLDKTIEETCNNAGY
                     LKLFFEKPRKNTVKLLLLMDSGGSMRGYSTLCNTLFQSVSKSNHFKDVKIYYFHNCIY
                     DRLFTTPECWLSKSINTEWILKNIDKNYKVIIVGDASMSPSELLHIGGNYRGPYNYTP
                     GIEWLKRFKRKYSKIVWMNPELRDGWDSISYWYQTQRMIQSEFNMFPLTVKGLEKALK
                     NLMVSR"
     gene            2360..5746
                     /gene="cspBA"
                     /locus_tag="ACGI5H_001803"
     CDS             2360..5746
                     /gene="cspBA"
                     /locus_tag="ACGI5H_001803"
                     /EC_number="3.4.21.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018112792.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional germination protease/germinant
                     receptor pseudoprotease CspBA"
                     /protein_id="HFG9697510.1"
                     /translation="MIIINYELIVKYNGDILRLEEELGVSVEILNSSYAIITSSNEED
                     VNILLTYPEIEFIEKPFILQTQDVQSFSSTGITGFKNRTGLTGKGTIIGIIDSGIDYT
                     LPVFRDSDGRSKILYYWDQSIQGNPPEGFREGTLYTNEDINNAIDGSMYIPISTTSLH
                     GTHVAGICATIASDARIIVVRVGNIQTDIFSRSTEFMRAIKFILDRALELRMPVTLNI
                     SYGSNEGSHRGTSLFEQYIDDMCLFWKNNIVVAAGNNADKGGHKRIRLQNNITEEVEF
                     IVGEGERILNINIWPDFVDDFSVHLVNPSNNQTQAISLTSGEIRNTLGETRITGYFYP
                     IAPYSLTRRVTLQLSSNTQITPGLWKIVFEPIDIVTGNVNIYLPTSEGLNRNTRFLIP
                     TQELTVTVPGTASRVITVGSFNSRTDIVSIFSGEGDTQLGVFKPDLLAPGEDIVSFLP
                     GGTSGALTGTSMATPHVTGVCSLFMEWGIVNGNDLFLYSQKLRALLLKGARRLSNQSY
                     PNNSSGFGFLNLSDIDLYTLSNINQDLETEDIGYRSINKSFKDEENSYKFIDGYNMQI
                     HNDLENEIYISKNASRQSGIDIVHTPEFEEELAGLGMSQRFFKISDSLGVLSINNTDY
                     NSIQRVLQLPSIIRTVSTTKMTLLGEINRGTFGGVVATEEMGVNFFKNNPNINITGRG
                     TLISIADTGIDYLHPDFIYPDGTSKIVYLWDQTKEGTPPDGFYIGTEYTREDINRAIA
                     ENDPSLSQDEVGQGTMLSGICAGLGNVNSEYAGIAEDSELIIIKLGKIDDFYNSAMLF
                     AASQYAYKKAFELGRPLVINMSLGTSSLAGLTNRSNSEKAFFTRGLCITAGAGNEGNT
                     QTHTSGIIPYVGGSVEVELELNEDEEELSLELWLNRPDKADVIIVSPTGEESKSVGIS
                     NYNKVTGLFDLEGTEYSITYIYPTTFSGQQFTNVTLKNAKRGVWKIRLVGVYIITGRY
                     NLYLPNRELLKSGTRFREVDPFYTINYPAIQDDLITIGAYNTINGSLWQSSSRGPTIE
                     DRLKPDIVAPGVNIIAAYPGNTYATITGTAAASAHAAGAAAMYFQYTFVDGRYPNQAY
                     VQKIKTFMQAGARKDSNTVYPNTNSGYGLLDVRGMFDVLR"
     gene            5756..7429
                     /gene="cspC"
                     /locus_tag="ACGI5H_001804"
     CDS             5756..7429
                     /gene="cspC"
                     /locus_tag="ACGI5H_001804"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430441.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bile acid germinant receptor pseudoprotease
                     CspC"
                     /protein_id="HFG9697511.1"
                     /translation="MEKSYCIIYQGDIESALQENGINRYMVLNSQLAVIYVPLDFDET
                     ILNNIIQVAWWEESEPMSSLIEITNNVNNGETITTAAETDYIYENPYNDITGRGILLA
                     VIDSGIDYLHPDFINDDGTSKVLYLWDQEANTNPPPEGFIFGSEFTRSELNIAINRND
                     GSLSQDNIGTGTLVSGILVGNGRINSQYRGITTESDLIVVKLKSYTDTYYAGRINYSV
                     SDFLAAITYVTNIARTENKPLIINLTIGVKSSAVATTSILDTFNILSSAGVVVVSGAG
                     NQGNTDIHYSGRFSSVGEVQDVIIQDGDDYALDITLNTNGPDKVGAQIISPSGEVSHD
                     IRYSPDFYIYRGKFNLENTTYAMRFIYPYITSGKENLEIRLRDIKPGVWILRLTSELI
                     INGEYDIYLPNKNLIAPDTRFLEPDSVATITMYAASDDVITVGTFNNKTDSMWIGSSK
                     GPIRGRGIKPDIVASGVDIISTYKNGTYNTGTGTGVSSSIVTGVLALLMEYLEKQDNV
                     PRLSLFTQVLKTYLILGATKLEIYTYPNVSQGYGILNLKNTIQQIANTL"
     gene            7702..7896
                     /locus_tag="ACGI5H_001805"
     CDS             7702..7896
                     /locus_tag="ACGI5H_001805"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890435.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3787 domain-containing protein"
                     /protein_id="HFG9697512.1"
                     /translation="MESKKARALKGKDNKRLKSSLLVGNESTAAWADVEKLKPHSKVS
                     IPSIKGVEEAKDWVDNGSKL"
     misc_binding    8065..8298
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            8375..9772
                     /gene="asnS"
                     /locus_tag="ACGI5H_001806"
     CDS             8375..9772
                     /gene="asnS"
                     /locus_tag="ACGI5H_001806"
                     /EC_number="6.1.1.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004816 - asparagine-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006421 - asparaginyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="asparagine--tRNA ligase"
                     /protein_id="HFG9697513.1"
                     /translation="MQKEFITVKELYREKEQYIGKTVKVAGWIRTSRVSKNFGFIELN
                     DGSFFKNMQIVFDEKVENFKEVGKLAISSSILVEGELVSTEGAKQPVEIHAKSIVVEG
                     ESDSSYPLQKKRHTLEYLRTIAHLRPRSNTFSAVFRVRSIAAYAIHKFFQERNFVYAH
                     SPIITGSDCEGAGEMFRITTMDLNDIPKTEDGKIDYTQDFFGKEANLTVSGQLNAEIM
                     ALSFRNVYTFGPTFRAENSYTGRHASEFWMIEPEIVFADLEDNMELAEDMIKYVISYV
                     LENAPEEMEFFNSFIDKGLLERLNKIVNSEFIRITYTKAVELLIESGHEFEYPVEWGC
                     DLQTEHERYITEQIYNCPVFVTDYPKDIKAFYMRMNEDGKTVRAMDLLVPGVGEIVGG
                     SQREEREDVLLDRINEMGLREEDYWWYLELRKFGTATHSGFGLGFERIIMYMTGMSNI
                     RDVIPFPRTPKNAEF"
     gene            complement(9945..11120)
                     /locus_tag="ACGI5H_001807"
     CDS             complement(9945..11120)
                     /locus_tag="ACGI5H_001807"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893536.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GGDEF domain-containing protein"
                     /protein_id="HFG9697514.1"
                     /translation="MNLEKIKKFFGFPLDKKHKDNVEKELCNYLYHTGKIICIIIVIS
                     QIIMMISISAREGGPFVTPRRQWYFYMYVTLFCVSSVFMFVFSYLWNKKKDCCTFYIN
                     LWIIYVTFFCLWGCVITLLDQLGGNDLSVFSYIMLAAAAFSVLKFGESVIVFGGCFLF
                     LNLFLPGIQTIPGNEFSNIVNTFFITSLAIFVSTMLYRNRVFTYYDKLLISQQYEEIS
                     HINNLLNDKVMTDDLTKMNNRRYLEDILQKKLISHANQEPITGMMIDIDYFKQFNDNY
                     GHQKGDYCLQNIAKVILDFTSSENEHAIRYGGEEFFICIFNCNEADAKLKSECLRKII
                     ESCNFERDDVPLKCVTVSIGVYTKKIGKTITLNEFISNCDKALYTAKEQGRNCVAFY"
     gene            11539..12903
                     /locus_tag="ACGI5H_001808"
     CDS             11539..12903
                     /locus_tag="ACGI5H_001808"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423322.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc ribbon domain-containing protein"
                     /protein_id="HFG9697515.1"
                     /translation="MGEKKINNMNYSHNNYSKKTGEPTRKIKNSHITLKSKEEKICSS
                     CNKENNTKDNYCKFCGNELYEIASLRPLETKLDLKSKIKELSYHANKRGVFLTTFTTI
                     FILFIIALIFKAIITIQFNDISYLINPAHIILALNLGQISVSMSTMMGSGFINANIGL
                     LILLIIPILVLLISNLIFMRKRCRDSKTVLANSLGVGIFYGLVLAILSIFTNVKTSSH
                     SMLEYGYALEYSYEFFSVLLNGFVLGFICTYITTYKKSYEKENMYLSLFSNSIRTFIL
                     GYVLVLVILLVLTISDSSYLNELDMSSYSNGLNLFTILPQIASYMWAFANGISVTIIN
                     STVSMFTLSSSSLFGDTKLMFYAMGALSMLILLLNGYKLRFKYNTDSIRPIIVFSIYY
                     AFLMGILALFSTFILDSNINFFNTTNYGTTLIMQFKVLQAIVISFVYSFVISLIGYKL
                     NSAD"
     gene            12925..13416
                     /locus_tag="ACGI5H_001809"
     CDS             12925..13416
                     /locus_tag="ACGI5H_001809"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430450.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc ribbon domain-containing protein"
                     /protein_id="HFG9697516.1"
                     /translation="MEGNTNNKVDDKFSKVKKKFGSGKFKVELYKEKSKLNREIDDIQ
                     EKKAKIFLEMGILTYQKIREDSINDNSFDKFCDELLELDKLIYEKNMEINEMEMAESN
                     VTCECGYVGNVNDKYCAECGKKFELENECDDFIICGYCESEIDTEAEFCPCCGRKIIM
                     DLE"
     gene            13689..14360
                     /locus_tag="ACGI5H_001810"
     CDS             13689..14360
                     /locus_tag="ACGI5H_001810"
                     /EC_number="5.1.3.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433825.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0009385 - N-acylmannosamine-6-phosphate
                     2-epimerase activity [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA];
                     GO_process: GO:0006051 - N-acetylmannosamine metabolic
                     process [Evidence IEA];
                     GO_process: GO:0019262 - N-acetylneuraminate catabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmannosamine-6-phosphate 2-epimerase"
                     /protein_id="HFG9697517.1"
                     /translation="MLDKVKGRLIVSCQALEDEPLHSPFIMGRMAKAAMEGGAVGIRA
                     QGVEDIIEIKKVTGLPVIGIIKRNYEDSDIYITPTKKEVDELLTTGCEMIALDATNRV
                     RPNNEDLKELIKYIKENGVLVMADISNYDEAIKAQEYGVDCVSTTLSGYTPYTKTLEG
                     PDFVLMERLVKDLEIPVIAEGKVNTPQDLKKVFELGVHSSVVGSAITRPQLITEKFVK
                     AIEIN"
     gene            14430..15311
                     /locus_tag="ACGI5H_001811"
     CDS             14430..15311
                     /locus_tag="ACGI5H_001811"
                     /EC_number="4.1.3.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729082.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008747 - N-acetylneuraminate lyase
                     activity [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylneuraminate lyase"
                     /protein_id="HFG9697518.1"
                     /translation="MRTTDMKGIYSALLVSFDKEGNINEKGLRQIIRHNIDVCKVDGL
                     YVGGSTGENFMLSTDEKKRIFEIAKDEVKEEIKLIAQVGSVNLKEAVELAKFTTDLGY
                     DAISAVTPFYYKFDFEEIKHYYNTIINSVDNRLIIYSIPFLTGVDMSLDQFGELFENE
                     KIIGVKFTAADFYLLERMRKTFPNKLIFAGFDEMMLPATVLGVDGAIGSTFNVNGVRA
                     RQIFELTKNEKISEALEVQHVTNDLITDILGNGLYQTIKLLLEEQGVEAGYCRQPMKE
                     ATDEMKSRAKEIYRKYF"
     gene            15344..16846
                     /locus_tag="ACGI5H_001812"
     CDS             15344..16846
                     /locus_tag="ACGI5H_001812"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430454.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sodium:solute symporter"
                     /protein_id="HFG9697519.1"
                     /translation="MVGFTWIDFAILVVYLLAVLFAGLLFSKKEMKGKEFFKGDGTIP
                     WWVTSVSIFATLLSPISFLSLAGNSYGGTWILWFAQLGMFIAIPLTIKFFLPLYSRLE
                     IDTAYEYLEMRYESKGLRVLGALMFIIYQIGRMSIIMYLPSIVLAGLTGIPVNVLIIV
                     MGVIAIIYSYTGGLKAVLWTDFIQGMVLIVGVTGTLFYLIASINGGFGTVMDTLTTGH
                     KFLASNEVMFDKNILSTSAFIIFVGAGLNTFSSYVSSQDIVQRFTTTTDIKQLNKMTY
                     GNGVLSMGLATVFYLIGTCLFIYYTQNPDLAQTVQQDQVFASYIAYELPVGITGILLA
                     AIYAASQSTLSTGLNSVATSWTLDIQTIITKDISMEKQTKIAQYISLGVGILSIAVAI
                     VLANGEIKSAYEWFNSFMGLVLGVLAGIFVLGAFCKKATKMGAYVGFIVSAILVVYLK
                     YRMPEVTSWAYSLITITTSVVVGTIVSAIEAKVKAKVSLPKAETTVYYEK"
     gene            16976..17428
                     /locus_tag="ACGI5H_001813"
     CDS             16976..17428
                     /locus_tag="ACGI5H_001813"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890423.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YhcH/YjgK/YiaL family protein"
                     /protein_id="HFG9697520.1"
                     /translation="MIFGNINHSKTYSTLHEDLLRCFEYAKDNSLIDYEKGTYTIDGD
                     DIFVNIVEYKTCEKEDRFWEAHKKYIDVHLMLDGCERIDINFIENLEQKIYEEKGDFL
                     PLDGKNNGYMELRKGDFLVCYPEDAHMTGIKVLEKENIKKAIFKVLVR"
     gene            17588..18391
                     /locus_tag="ACGI5H_001814"
     CDS             17588..18391
                     /locus_tag="ACGI5H_001814"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433827.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sialate O-acetylesterase"
                     /protein_id="HFG9697521.1"
                     /translation="MENIDVFLLIGQSNARGLGNPKESIIPNENCFEYLSTDEIINMR
                     CELETSEGDGTIAPAFSNEWNKLTGNKVCFIHNAKDGSRIKNWNHDNNWFLNDTIEKF
                     NTGCTTLSKHYNIENKYVIWIQGESDAKYGSDVLYYKESLKKIAYRLKEECMIDKMFV
                     SLTGYWLGEDEYFIRTRRIAAAQESACSECDILCVGSKIAMQFHDRGLTIDDVHYTQE
                     GLNMLGEDLCKNIYKYHITKEKSVLSDTIDLSEARKYICELEKISKRFV"
     gene            18449..19336
                     /locus_tag="ACGI5H_001815"
     CDS             18449..19336
                     /locus_tag="ACGI5H_001815"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423341.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="HFG9697522.1"
                     /translation="MKNYVCIDVGGTSIKYGFIREDGFIIDKSSLDTEAKEKGGEGIL
                     AKIKDIVKKYIEENEISGICISTAGMVDPVEGKILFALEELIPNYKGMQLKKEVEKEF
                     NIKCEVENDVNCAGLGEMWLGAGKDATSSICLTIGTGIGGCIIINNKLINGFSNSAGE
                     VGYMNVNGSSFQELASTSSLIKKVAKIKNLNENDLNGKIIFDLAKNNDEDCLKELDNM
                     IKSLAVGIANICYVINPEVVILGGGIMAQEKFLKPKIDKALKEVLIERVYKNTNIEFA
                     KRQNDAGMLGALYNFLNKI"
     gene            19355..20203
                     /locus_tag="ACGI5H_001816"
     CDS             19355..20203
                     /locus_tag="ACGI5H_001816"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433168.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MurR/RpiR family transcriptional regulator"
                     /protein_id="HFG9697523.1"
                     /translation="MSILEQLESPTFKVTKSDKLLIAYIKENIDDVFYKPISQIAKES
                     NIGEATITRFVKKMNFNGLQDFKVTLAQEISTINKKNIINKNIQNDEPALDTAKKLLS
                     SNVTTLENTVEIINSKDVHDCARLIINAKKVYFIGIGYSGIIAQDSNYKFMRIGLNCV
                     SFDSSHTMIMMSSIMEEGDLIIAISHSGETEEIIKTVKLARANNAKIISITENKNSEL
                     KDISDVHLSYVSGETVLETGSISSKLAQFFIIDLVYTQVVKELSNEAIERKIKTTNAI
                     KLFKNE"
     gene            20266..20955
                     /locus_tag="ACGI5H_001817"
     CDS             20266..20955
                     /locus_tag="ACGI5H_001817"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018112794.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_function: GO:0030552 - cAMP binding [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Crp/Fnr family transcriptional regulator"
                     /protein_id="HFG9697524.1"
                     /translation="MSKLKDYNIDKVIIFNNLSTKTKNQLKEKVKLKRLQKKEILFYE
                     KDSLDSVYILLEGKVSIFKISENGERKVIFILNSGEVINDITLDASKNSTVGCEAFEN
                     SIVAYYSIEEFLEIMQNDFQLTKDIISYMERRIRRLYRQLKNSISIKVDKKLAAKLYR
                     LSREFGVCCGEWTLLNVNITVTYLADMLGCKRETVSRMIKVLQKEELIKIDNKGFYVK
                     ETELSRYFKNN"
     gene            21346..22353
                     /gene="asrA"
                     /locus_tag="ACGI5H_001818"
     CDS             21346..22353
                     /gene="asrA"
                     /locus_tag="ACGI5H_001818"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903096.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0009055 - electron transfer activity
                     [Evidence IEA];
                     GO_function: GO:0016002 - sulfite reductase activity
                     [Evidence IEA];
                     GO_process: GO:0006790 - sulfur compound metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="anaerobic sulfite reductase subunit AsrA"
                     /protein_id="HFG9697525.1"
                     /translation="MKLKLDSSKFNEGLNYLKKDYKIFAPVLIPFKGTFSDTDVIRYK
                     EVNAFEEMEFAKKANFSPKEVVLPINQVLFYFTEKEFKESDLDNKKILIFLRACDING
                     IKRLDEIYLNNGEEKDYFYKNIRDKVKFALVGCKESFRNCFCVSMDSNKTDNYSIGLN
                     IEGDTLYLDIKDSEFEVFNGEATEFNVDYVTDNLISVDVPENIDSNEMIGNSIWDEYD
                     TRCIGCGRCNFVCPTCSCFTMQDIFYKENENVGERRRVWASCQVDGYTDIAGGNSFRK
                     KQGERMRFKTMHKIHDFKKRFGYHMCVGCGRCDDACPQYISFSKCIEKINDLVISKEE
                     V"
     gene            22354..23145
                     /gene="asrB"
                     /locus_tag="ACGI5H_001819"
     CDS             22354..23145
                     /gene="asrB"
                     /locus_tag="ACGI5H_001819"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0009055 - electron transfer activity
                     [Evidence IEA];
                     GO_function: GO:0016002 - sulfite reductase activity
                     [Evidence IEA];
                     GO_process: GO:0006790 - sulfur compound metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="anaerobic sulfite reductase subunit AsrB"
                     /protein_id="HFG9697526.1"
                     /translation="MNPYIPVSAKILDIVKHTDKEWTFRVNCNTKGVLPGKFYEISIP
                     KYGESPISVSGYGEDYIDFTIRNVGKVTSELFNYKEGDSFFIRGPYGNGFDVSLYEGR
                     EIVVVAGGSALAPVRGIVEYFYNNKEKCEKFKLIVGFKSPKDILFADDLKRWSKKLDI
                     LVTVDGAEEGYSGNVGLVTKYIPELDMKDINNTSIVVVGPPMMMKFTVEEFLKRDLDE
                     KNIWVSYERKMCCGIGKCGHCKMDDTYICLDGPVFDYSYAKNLID"
     gene            23158..24129
                     /gene="asrC"
                     /locus_tag="ACGI5H_001820"
     CDS             23158..24129
                     /gene="asrC"
                     /locus_tag="ACGI5H_001820"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430464.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016002 - sulfite reductase activity
                     [Evidence IEA];
                     GO_process: GO:0006790 - sulfur compound metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sulfite reductase subunit C"
                     /protein_id="HFG9697527.1"
                     /translation="MIRDLNTKKVMKNAYRITKTKYETSLRVRVPGGLIDPESLAVVS
                     KIASEYGNGQVHITTRQGFEILGINMEDMEEINKIIQPVIEKMNINQSEKNAGYPAAG
                     TRNIAACIGNKVCPKAQYNTTEFAKRIEKAIFPNDLHFKVALTGCPNDCIKARMNDFG
                     IIGMALPIYEKDRCVNCGACVKKCSKISVGALKTENNKVVRDKDKCIGCGECVLNCPT
                     NAWTRDEKKYYRLAIMGRTGKKNPRLAEDFLLWVDEDSIIKIILNTYRYVEKYIDKDA
                     PGGKEHIGYIIDRTGFMEFKKWALEGVELPEITKMYENIYWSGIKYL"
     gene            24186..24962
                     /locus_tag="ACGI5H_001821"
     CDS             24186..24962
                     /locus_tag="ACGI5H_001821"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729086.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_function: GO:0015499 - formate transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0015724 - formate transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="formate/nitrite transporter family protein"
                     /protein_id="HFG9697528.1"
                     /translation="MHKETLDKLTNAAINKINLLNTSKVKYLVSSAFAGLYVGIGILL
                     IFTIGGLLTDAGSPMTKIVMGLSFAIALSLVIMTGTELFTGNNMVMSAGMLNKGVSIK
                     DTSKIWAYSWVGNLIGALVLGIIFVGTGLIDKGPVAEFFANTAASKASMPFTALFFRG
                     ILCNILVCVSVLCSFRTNSDTAKIIMIFLCLFAFITSGFEHSVANMTIYSVSLFSPTI
                     NTVTIGGAIYNLVAVTLGNIVGGALFMGLGTYILGKEKLN"
     gene            25233..27251
                     /locus_tag="ACGI5H_001822"
     CDS             25233..27251
                     /locus_tag="ACGI5H_001822"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729087.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="FUSC family protein"
                     /protein_id="HFG9697529.1"
                     /translation="MTKKLVISKTKLFIFIIAFISIFIYLFGSKNTLIGVGIVTAMLT
                     LLERDLTISPIKNLLKYLAINIILGILSFFAVQNMYLGVLLNFIALFIIGYVFSYDLK
                     RAVYVPFGLMYIFMVSIPVGKSEFPMRLSALAVGAVIIMIAQFVMNRNRMKNVGDKEL
                     ISICDELLEKISLLKNTINDDSSIIKSSMRKIDSCNYRINSISKNLKMVIFDNRKDDF
                     YISIRGIDIMNILFSLERISLILERYKKDSKEFEDEDIKNILEESSINSKSDVLVVAT
                     KEINYIKMCLENKDTITDKEILGFRDYVIAQDTKNINLKEIYSVLENLYEFLVDYKKV
                     KSRDEKKAERKSKIPHEFKRLSIYKKNFNLNSIRFSYAVKIALATAVAGFIMDYFHLR
                     DGRWIMLTVFSLTQPYAENCIQRSRKRIEGTFIGAVIFIVLFSIIKDSTLRSLIVLLA
                     GYINSYVVDYRKLMVCVTVSALGSAVVMGDPNVLTISRISYVALGAIIALIVNKFILP
                     YDAKTGYQHVIEMYKGIVKNIIDEVNKSIENVADVYYIKNLLLIPSLIEDRLMLINAI
                     YKDKHQEDFLENQKLLISNMYNLYINVNKNKIKDEDVEKILRDTNYISNYNVDKYDEG
                     RSVILESIINTKSLGDKIICLNLLQTLNGVKEMYRISNITKVSIKEAA"
     gene            27466..28323
                     /locus_tag="ACGI5H_001823"
     CDS             27466..28323
                     /locus_tag="ACGI5H_001823"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890403.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HFG9697530.1"
                     /translation="MSKDVKVKRNKKYDTFSITMELERPLLYDEVENKDDKNNNRKFN
                     IKNKIFKGIGILFVLILLGFFIWINKTYEPQKLAKEALVSNSKVEVTVNENISFTPKG
                     RKVSKGLILYPGAKVEIESYAPLARKIAESGYEVVIVKMPLNLAILGTNKAQKVMDSY
                     NNIEHWVIGGHSLGGVAASNFARDNKLIEGVVFLASYPMGDELKELGKKVISIWGSKD
                     GVVNFKSLVESKQKLPDDTTYVEIEGGNHAQFGDYGKQKGDNDAIISQEKQLNITANS
                     IIKFLKNIS"
     gene            28420..29289
                     /locus_tag="ACGI5H_001824"
     CDS             28420..29289
                     /locus_tag="ACGI5H_001824"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003824 - catalytic activity [Evidence
                     IEA];
                     GO_function: GO:0051539 - 4 iron, 4 sulfur cluster binding
                     [Evidence IEA];
                     GO_function: GO:1904047 - S-adenosyl-L-methionine binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="radical SAM protein"
                     /protein_id="HFG9697531.1"
                     /translation="MEYDMPLYRPPSEAYSLIIQVTLGCSHNKCTFCSMYKSKKFKIK
                     PLEVIKNEIDIFRRYYKHVERIFLADGDALIIPMEKLRDIILYIKEVFPECERITMYG
                     SPKSIEKKSDDELKELRKLGVKMIYLGLESGSNEVLEDIKKGFSSEQLIKVGRKVKKS
                     GIKLSATVIAGLGGTKKTHQHAVDTGKMLGAISPDYVGVLSLMVEPNTELYDLLKAGE
                     FTILEDKAVLQEIKEMIKNIDANEKIVFRSNHASNYANLKGVLPDDKQRLIDEIDYYL
                     SNQKLKREEYRRL"
     gene            complement(29659..30291)
                     /locus_tag="ACGI5H_001825"
     CDS             complement(29659..30291)
                     /locus_tag="ACGI5H_001825"
                     /EC_number="2.3.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433837.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016746 - acyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0046677 - response to antibiotic [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="CatB-related O-acetyltransferase"
                     /protein_id="HFG9697532.1"
                     /translation="MTIPSSNKVYPRSNDYQTVYLKNVITRENIEVGDYTIYNDFYND
                     PRDFEKNNVLYHYPINNDKLIIGKFCSIACNAKFLMTSGNHSMKSKSTYTFPIFYEEW
                     KLDINHITDAWDNKGNIIIGNDVWIGYDSIIMSGVNIGDGAIIGTRAVVTNDVPPYSI
                     VGGVPAKIIKKRFNNDTISKLLEIKWWDWPYKKIQSNIKHIQSGNIDKLV"
     gene            complement(30384..30716)
                     /locus_tag="ACGI5H_001826"
                     /pseudo
     CDS             complement(30384..30716)
                     /locus_tag="ACGI5H_001826"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009271880.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="integrase DNA-binding domain-containing protein"
     gene            complement(30794..30997)
                     /locus_tag="ACGI5H_001827"
     CDS             complement(30794..30997)
                     /locus_tag="ACGI5H_001827"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002262306.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="excisionase"
                     /protein_id="HFG9697533.1"
                     /translation="MNNTDVPIWEKYTLTIEEASKYFRIGEKKLRKRADENLDSGWVI
                     MNSNRIQIKRKQFEKIVDTLDVI"
     gene            complement(31387..31617)
                     /locus_tag="ACGI5H_001828"
     CDS             complement(31387..31617)
                     /locus_tag="ACGI5H_001828"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897394.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HFG9697534.1"
                     /translation="MKPTKEVLPFTIILLAVHGDVNAINVILKHFEHYIIRLSQKTLF
                     DEYGNPYIHVEEETKRMLGTKLITAILRFNLS"
     gene            complement(31619..32026)
                     /locus_tag="ACGI5H_001829"
     CDS             complement(31619..32026)
                     /locus_tag="ACGI5H_001829"
                     /inference="COORDINATES: protein motif:HMM:TIGR02937.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_function: GO:0016987 - sigma factor activity [Evidence
                     IEA];
                     GO_process: GO:0006352 - DNA-templated transcription
                     initiation [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-70 family RNA polymerase sigma factor"
                     /protein_id="HFG9697535.1"
                     /translation="MVDEKTIEHQFDSFCKTVLRNYARDIYDENKRRNDYLVSLESLS
                     LAELSKLSILDDYDSNYICMVSYDYNIRIEDVLMAQAIGKLTKRKQDIILLSFFFNMT
                     NADIATLMDLAENTIHYHKTNALKELKELMQEH"
     gene            complement(32386..32835)
                     /locus_tag="ACGI5H_001830"
                     /pseudo
     CDS             complement(32386..32835)
                     /locus_tag="ACGI5H_001830"
                     /inference="COORDINATES: protein motif:HMM:NF024698.4"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:0016746 - acyltransferase activity
                     [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
     gene            complement(32849..33775)
                     /locus_tag="ACGI5H_001831"
     CDS             complement(32849..33775)
                     /locus_tag="ACGI5H_001831"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903090.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9697536.1"
                     /translation="MSDILSRITNKIGDKNIVDKLSALSKSDLNSLLLEVFDRQANTL
                     TATDILKSYQLNRFTIPSGIDPEEIHALESKLLRKAFNMDIKTIMLSPSAPLGSCSVF
                     GSVDQYNVVSALRGTETLADPSNMLAIIIADKLKRKEENNTIPIHMATTARVIRAQNF
                     VGKGLYSHFGLYCMVSSGIDTGSYTCEKMLLEKHLNYYKDILSEIENVRFSIILRKRN
                     GYKDNDGFFDRMVETIKLIFPNIELSIHNDDVDNNYYKGINFKLSVKQGNETVEIVDG
                     GFVDWTYQMLGNKRERCLISGIGLERFLVAVS"
     gene            complement(33900..34682)
                     /locus_tag="ACGI5H_001832"
     CDS             complement(33900..34682)
                     /locus_tag="ACGI5H_001832"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433844.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoglycoside 6-adenylyltransferase"
                     /protein_id="HFG9697537.1"
                     /translation="MTKTQQKMIQNVLEFSKRDSRIIGLAISSSYITKSLDEYSDLDF
                     LIVADDKSYEEVIEERLLIVEQFGTLVSAFTGEHVGEPRLIISLYDSPVLHVDFKFTT
                     LDGLLDRVEDSAILYEENNCITEIYSKKEAYFPTPDLQWIEDRFWIWVHYACTKIGRR
                     ELFETIDFLSFLRQSVLAPLIQLLLGKLPRGVRKIELDAPQYIEALEKTVANHEYKSC
                     VNALQATINLYLELREELSQSPIVRKVEAERVALQYFQDLIK"
     gene            complement(34838..35458)
                     /locus_tag="ACGI5H_001833"
     CDS             complement(34838..35458)
                     /locus_tag="ACGI5H_001833"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423956.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_function: GO:0030552 - cAMP binding [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Crp/Fnr family transcriptional regulator"
                     /protein_id="HFG9697538.1"
                     /translation="MHLIDFMNEDIKKKLVKKTYKKKETILFAEQENEYVILMIDGIA
                     EAFILNVKGNISTIHLYRSGSFFGEMEQFNDGKKPVEIVAFTDCNVYKLHRDDFLNWL
                     RGDFEATKFLIREISSKLVVNAELIEELSSLSVKERLLRCISLHYYRSELNLLTKKQL
                     ASEVNAPIRSINRAINECVQEHLIAYENKRFSVINQREVLKNLPTT"
     gene            complement(35585..36253)
                     /locus_tag="ACGI5H_001834"
                     /pseudo
     CDS             complement(35585..36253)
                     /locus_tag="ACGI5H_001834"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000331151.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
     gene            36324..37160
                     /locus_tag="ACGI5H_001835"
                     /pseudo
     CDS             36324..37160
                     /locus_tag="ACGI5H_001835"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020220015.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
     gene            37832..38599
                     /gene="aroD"
                     /locus_tag="ACGI5H_001836"
     CDS             37832..38599
                     /gene="aroD"
                     /locus_tag="ACGI5H_001836"
                     /EC_number="4.2.1.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897376.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003855 - 3-dehydroquinate dehydratase
                     activity [Evidence IEA];
                     GO_process: GO:0009423 - chorismate biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type I 3-dehydroquinate dehydratase"
                     /protein_id="HFG9697539.1"
                     /translation="MKRKVQVKNITIGEGRPKICVPIIGKNKKDIIKEAKELKDACLD
                     IIEWRVDFFENVENIKEVKEVLYELRSYIHDIPLLFTFRSVVEGGEKLISRDYYTTLN
                     KEISNTGLVDLIDVELFMGDEVIDEVVNFAHKKEVKVIISNHDFNKTPKKEEIVSRLC
                     RMQELGADLPKIAVMPQNEKDVLVLLEATNEMFKIYADRPIITMSMSGMGVISRLCGE
                     IFGSALTFGAAKSVSAPGQISFKELNSVLNLLHKSIN"
     gene            complement(38927..39604)
                     /locus_tag="ACGI5H_001837"
     CDS             complement(38927..39604)
                     /locus_tag="ACGI5H_001837"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433851.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9697540.1"
                     /translation="MIVIEGSDKFKIAKEYIDVEYTLFSKVTFRYEKLKFKDNAELEK
                     IKMFKYKNGYIPNKLNLSFGYGFSSYKKQIIRETVDTLRLTEIFSSENIEDIKFIKDG
                     TKKLEISIEKVVKFKRRKKRNYVCCYCPDMYRDIKLDKESINKIYNRKIKIEREVNIF
                     EDEDVIINKKVLKFPKSWTKNMQKYWLSENKYPIHSTVIDDDRYKCCNVQYTKNRVII
                     LYYIYNH"
     gene            complement(39754..40071)
                     /locus_tag="ACGI5H_001838"
     CDS             complement(39754..40071)
                     /locus_tag="ACGI5H_001838"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890395.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HFG9697541.1"
                     /translation="MNYIGKRLKEERKKANLTSKEFANMVGVSPWYITQIESGKKNPS
                     LKTFIKFVNILNISADVLIKDITSTGKTYLENDINEELKDLNSRELNLISQIIDIIKK
                     NKI"
     gene            complement(40093..40431)
                     /locus_tag="ACGI5H_001839"
     CDS             complement(40093..40431)
                     /locus_tag="ACGI5H_001839"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423377.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HFG9697542.1"
                     /translation="MANIGKIIGDRIKVYRTKLGYSQEFLAEKAGLHPTYIGQIERAE
                     TNTSINIIMKIATALDIPLELLFANIITTEGVDNSVPLECYEMINKLTEKEQIAMLEL
                     IKCIIKYKEI"
BASE COUNT        15489 a         4744 c         6874 g        13709 t
ORIGIN      
        1 aaagataaaa attaaatatt ttagaggtga ttttatttag atatagaatt ttagaataat
       61 actatacaaa tgtattgtat tattattttt atatcaaaaa tagtaataaa gtctatatac
      121 atttagaaaa tactgtttaa aaggagtagg atttatgata aaaaaagaga tatctaactt
      181 tagaggaagt agtgattatg tagtatcacc agaattgatg gcatcagtta atgttgctat
      241 tgctcttgaa aagccacttt tgattaaggg cgaacctgga acaggtaaaa ctatgctagc
      301 acaagcaatt tcaaatgaat taaaaaaaga tttagtaatt tggaatataa aatcaactac
      361 aaaagcacaa gaagggcttt atgtatatga tactgttcaa agactttatg atagccaatt
      421 tggaggagaa ggtgtagatg atattagcaa gtacataaaa tatggtaaac taggagaggc
      481 ctttagctca aatcaacaag taattctttt aatagatgaa atagataagg cggatttaga
      541 atttccaaat gacttgcttt gggaattgga taaaatggag ttttacataa atgagacaaa
      601 agaaactgta agagctaaac aaagaccaat agttattata acttcaaatg cggaaaaaga
      661 acttccagat gcttttttaa gaagatgcat atttcattat atagaatttc ctgatagaga
      721 catgatggaa gaaatagtta aagtacattt tgataaagta gaagaacacc tattggaaca
      781 agtaatgact actttttatt ggattagaag tttaaaggac atacaaaaaa agcctagtac
      841 atcagagtta atagactgga tacaagcatt aactttgagt ggaatgccta ttgaaaaaat
      901 agaaaaagaa gttccttttg caggaatact acttaagaat aatgaggata ttgaatctat
      961 gcaaagacac ttatagttaa taggagctgg ataattatgt ttattgaatt tttttattta
     1021 ttgaggtcaa gaggattaaa tgtatcttta aatgaatgga tgactttaat tgaagcattg
     1081 gataaaggac tgtgctattc aaacttttca aatttttact atctttgcag gatgatttta
     1141 ataaaaagtg aaagtgattt tgataagttt gatgcagtgt ttttggagta ttttaaaggt
     1201 atagaacacc aagaagaaat tccagaagag attatgaatt ggcttaaaaa accagatata
     1261 gatttagaag agtttgaaag attagaacaa aatccaaata taaatcttga taaattaaga
     1321 gctaaattgg aggaacgaat aaaagaacaa gattctcctc ataatggtgg taattattgg
     1381 ataggcacag gaggcacttc agagttagga cattcaggaa aagggcaaac tggtatacgt
     1441 ataggtggaa attctactta tggtagagct gttcttgaag ttgcaggaga aagaaaatac
     1501 agagatttta gagatgatga agttttaaat atgcgtcaat ttcaagttgc actaaagaga
     1561 cttcgtcaat tttctactag aatagatgct ccaaagacag agcttgattt ggataagact
     1621 attgaagaga cttgtaataa tgcaggatat ttaaagttat tttttgagaa gccaagaaaa
     1681 aatacagtga agcttttatt gcttatggat tcaggtggtt caatgagagg gtatagcact
     1741 ttatgtaata cattatttca gtctgtaagt aaatcaaatc attttaaaga tgtaaagata
     1801 tattatttcc ataactgtat ttatgataga ttatttacaa cacctgaatg ttggttaagt
     1861 aaatctatta atactgaatg gatattaaaa aatatagata aaaactataa agttataatt
     1921 gttggagatg cttctatgtc gccttctgag ttgcttcata ttggtggtaa ctatcgtggt
     1981 ccatataatt atacacctgg tatagagtgg cttaaaaggt ttaagagaaa gtacagtaaa
     2041 attgtatgga tgaatccaga acttagagat ggatgggatt caattagtta ttggtatcaa
     2101 actcaaagaa tgatacaaag tgaatttaat atgtttccat tgactgtaaa aggtcttgag
     2161 aaagcattga aaaatttaat ggtttcaaga taaagtaaat ataaatgatg gtatgattta
     2221 ttcaaaattg taccatcatt atttattttt ttaatatatc tattataaat tgtataactg
     2281 aaacttaaaa aattatatag tctaatacat tttagactca cacaaaacat atacattaat
     2341 aataatttta gaagtcgagg tgattataat aaattatgaa ttaattgtaa aatacaatgg
     2401 agatatattg aggttagaag aagaattagg tgtatcagta gagatactta attcatcata
     2461 tgcaataata acatcaagta atgaagaaga tgtaaatata cttttaactt atccagaaat
     2521 tgaatttata gaaaagcctt ttatattaca gactcaggat gtgcaaagtt tttcaagtac
     2581 aggaataaca ggatttaaaa atagaactgg tttaactgga aaaggaacta taattggtat
     2641 aattgattcg ggaatagatt atactctacc tgtgtttaga gatagtgatg gaaggtctaa
     2701 gatattatat tattgggacc aatctattca aggaaatcca ccagaaggtt ttagagaagg
     2761 aacattatat actaatgaag atataaataa tgcaatagat ggaagtatgt atatacctat
     2821 ttcaacaact agcttacatg gaacacatgt tgcaggtatt tgtgcaacta ttgcaagtga
     2881 tgccagaata atagtggtta gagttggaaa tatacagacc gatatttttt cgagaagtac
     2941 agagtttatg agggcaatta aatttatttt agatagggca ttagaattaa gaatgcctgt
     3001 tacattaaat ataagttatg gaagtaatga aggttcacat agaggaacat ctttatttga
     3061 acaatatata gatgatatgt gtttattttg gaaaaacaat atagttgtag cagctggaaa
     3121 taatgcagat aaaggaggtc ataaaaggat taggcttcaa aataatatta cagaagaagt
     3181 tgagtttata gttggggaag gagagcgtat attaaacata aatatatggc cagattttgt
     3241 tgatgatttt agtgtacatt tggtaaaccc atcaaataat caaacacaag caatctctct
     3301 aacttcaggt gagataagga atactttggg tgaaactaga ataactggtt atttttaccc
     3361 tatagcaccg tattctctca caagaagagt tactctacaa ttaagttcaa atacacagat
     3421 aactcctggg ttatggaaaa ttgtatttga accaatagat atagtaactg gtaatgtaaa
     3481 tatatatttg ccaacttctg aaggtctaaa tagaaatact agatttctga ttcctactca
     3541 agagcttact gtaacagttc ctggaacagc aagtagagtt ataacagtag gtagttttaa
     3601 ttcaagaaca gatatagtat ctatattttc tggtgaagga gatacacaat taggtgtttt
     3661 taaacctgat ttattagctc caggtgaaga tatagtatct tttttaccag gaggtacaag
     3721 tggagcatta actggaacta gcatggctac acctcatgtt acaggggttt gttcattgtt
     3781 tatggaatgg ggaattgtaa atggaaatga tttatttttg tattcacaga aattaagggc
     3841 attacttcta aagggagcaa ggagattaag taatcaatct tatccaaata attcatcagg
     3901 atttggtttt ttaaatttat cagatataga tttgtacact ctatctaata taaatcaaga
     3961 tttagaaaca gaggatattg gatatagaag tattaataag tcatttaaag atgaggaaaa
     4021 tagttataag tttatagatg gttataatat gcaaatacat aatgacttag agaatgaaat
     4081 ttatataagt aaaaatgcaa gtagacaatc aggaatagat atagtccata ctcctgaatt
     4141 tgaagaagaa ctagctgggt taggtatgag tcaaaggttt tttaagataa gtgattcatt
     4201 aggtgtacta tctataaata atacagacta taatagcata caacgagttt tgcaacttcc
     4261 ttcaatcata agaactgtat cgactacaaa gatgacatta cttggagaaa ttaatcgagg
     4321 tacttttgga ggtgtagttg caacagaaga aatgggcgta aatttcttta aaaataatcc
     4381 taatattaat ataacaggaa gagggactct aatatcaatt gcagatacag gaatagacta
     4441 tctacaccca gattttattt atccagatgg cacttcaaaa atagtatatt tatgggacca
     4501 aacaaaagaa ggaactcctc ctgatggttt ttatattggg acagaatata cacgagaaga
     4561 tataaatcga gctatcgcag aaaatgaccc tagtctatct caggatgaag ttggtcaagg
     4621 aactatgttg agtgggatat gtgcagggct tggaaatgta aatagtgaat atgcaggtat
     4681 agcagaagat tctgagctaa taataataaa actcggcaag atagatgatt tttataatag
     4741 tgcaatgttg tttgctgcat ctcagtatgc atataaaaaa gcttttgaac ttggaagacc
     4801 attagttata aatatgtctt taggtaccag tagcctagca ggtttaacca ataggagtaa
     4861 tagtgaaaaa gcgttcttta ctagagggtt atgtataacg gcaggagcag gaaatgaggg
     4921 caatacacag acacatacat ctggaataat accatatgtt ggaggttctg ttgaagttga
     4981 attagagtta aatgaagacg aggaagaatt atcattagaa ctttggttaa atagaccaga
     5041 taaagctgat gtaataatag tatctcccac tggtgaagaa agtaaaagtg ttggaatttc
     5101 aaattataat aaagtaacag gtttatttga tttagagggg actgaatatt ctataacata
     5161 tatataccca acaacttttt ctggacagca atttactaat gttactttaa agaatgcaaa
     5221 aagaggtgta tggaagattc gattagtagg agtttatatt ataacaggaa gatataactt
     5281 ataccttcca aatagagaac ttttaaaaag tggaactaga tttagagagg tagacccttt
     5341 ttacactata aattatcctg cgattcaaga tgatttaata accataggag cctacaatac
     5401 cattaatggt agtttatggc aaagttcatc aagagggcca actattgaag acaggttaaa
     5461 accagatata gtagcaccag gtgtcaatat aatagctgct tatcctggga acacgtatgc
     5521 aactataact ggtacagcag cagcaagtgc acatgcagct ggtgctgctg caatgtattt
     5581 tcaatatact tttgttgacg gtagatatcc aaaccaagca tatgtgcaaa aaataaaaac
     5641 ttttatgcaa gctggtgcta gaaaagattc aaacacagta tatccaaata caaattctgg
     5701 atatgggctc ttggatgtta gaggaatgtt tgatgtttta agataggagg gatttatgga
     5761 aaaatcttat tgtataattt atcaaggtga tatagaatct gccctacaag aaaatggaat
     5821 aaataggtat atggttttaa atagtcagct tgcagtaata tatgtacctt tagattttga
     5881 tgaaactatt ttaaataata taatacaagt tgcttggtgg gaagaatctg aaccaatgag
     5941 cagtctaatt gaaataacta ataatgtaaa taatggagaa accattacaa cagcagctga
     6001 aactgattat atttatgaaa atccatataa tgatataaca gggagaggaa ttttattagc
     6061 agttatagat tctgggatag attatttgca tcctgatttt ataaatgatg atggaactag
     6121 taaagtttta tatttatggg accaagaagc aaatacaaat ccacctccag aaggttttat
     6181 ttttggaagt gaatttacaa gaagtgagtt aaatatagcc ataaatagaa atgatgggag
     6241 tttgagtcaa gataatatag gtactggaac tttagtttct ggtatattag ttggaaatgg
     6301 aaggataaat tctcagtaca gaggtattac tacagaatca gacttaatag tagttaaatt
     6361 aaaatcatat acagatactt attatgctgg aaggataaat tacagtgttt cagatttttt
     6421 agcagctata acgtatgtta ctaacatagc aagaacagaa aataaaccac tgataataaa
     6481 tttgactatt ggagttaagt caagtgctgt agcaactact tcaatactag atacttttaa
     6541 tatattgagt agtgctggtg tggtagtagt gagtggtgca ggaaatcaag ggaatacaga
     6601 tattcattat tctggcagat ttagcagtgt gggagaagtt caagatgtaa taatacaaga
     6661 tggagatgac tatgctcttg atataacact aaatacgaat ggtccagata aagtgggagc
     6721 acagataata tctccttcag gtgaagttag tcatgatata aggtattctc cagactttta
     6781 tatatataga ggaaaattta acttagaaaa tactacttat gcaatgagat ttatttatcc
     6841 atatattacc tctggaaaag aaaatttgga gataagatta agagatataa aacctggagt
     6901 atggatttta agattgactt cagaacttat aataaatgga gaatatgaca tatacttgcc
     6961 aaataaaaat ttgatagctc cagacacaag gtttttagag cctgattcag tagctactat
     7021 aactatgtat gctgctagtg atgatgtaat tacagttggt acatttaaca ataagactga
     7081 tagtatgtgg attggttctt cgaaaggacc aattagagga agaggaatta agccagatat
     7141 agtagcttca ggtgtagata taatatccac atataaaaat ggaacatata atacaggaac
     7201 aggaacagga gtgagcagtt ctatagtcac aggtgtttta gccttattga tggaatactt
     7261 agaaaaacag gataatgtac cgagattatc attgtttaca caagttttaa aaacatattt
     7321 aatattgggt gctacaaaac ttgagatata tacatatcca aatgtatcgc agggatatgg
     7381 gattttaaat ttaaaaaata cgattcaaca gatagcaaat actctataga taagaaccta
     7441 tgtaaaatta taattgatta ttagtttaat tgtatcaaat actttagata gagtagaaaa
     7501 atagcataaa aaataaatat gaaaattaaa aaacagtttt atattttgaa tacacaaagt
     7561 aaatattttg tatataaata ggtataaatt aagtattgaa aagatattat gttaatttaa
     7621 aaataattat aatttagact tatgaatttt atttgtaaaa ttgctaaaac tattacaaaa
     7681 taaataatag aggtgatagt tttggaaagt aaaaaggcaa gagcattaaa aggtaaagat
     7741 aataaaagac ttaaaagttc acttttagtt ggaaatgagt cgacagcagc atgggctgat
     7801 gttgaaaaat taaaacctca tagtaaagtt tcaatacctt caattaaggg tgtcgaagaa
     7861 gcaaaagact gggttgacaa tggaagtaaa ttataaaatt ttggaaattg aagtaataaa
     7921 gaagtaatga agataagtat ttattatcat tatgtaaggt agaattatta tattttaaat
     7981 aacaatcagt atcaattata taaatttatt gactaaaaat ttataaattg gtataatttt
     8041 gttaattagc agaaataata aaagataaat actgtgaaga gaagagtaga tataaaatgt
     8101 agttctagcg agttgaggat ggtgaaagct caatacgagg tttatattga agaacatctt
     8161 ggagtttcta atcgaaagct tatttagtaa gtagacttag acggaaggca ccgttatagg
     8221 ctttaagcat tgcttaacta agaggtcatt atgacaacta gggtggtacc gcgagagtaa
     8281 tagtctttcg tccctttata tagggatgaa gggctttttt tattgaaatt atatttaaaa
     8341 gaaattaata acaattatac taggaggatt taaaatgcaa aaggaattta taacagtaaa
     8401 agaattgtac agagaaaaag aacagtacat agggaagact gtaaaagtag ctggatggat
     8461 aagaacatct agagtatcta aaaattttgg atttatagag ctaaatgatg gaagcttctt
     8521 taaaaatatg cagatagtat ttgatgagaa agtagaaaat tttaaagagg taggaaaatt
     8581 agcaataagc tcatctatac ttgtagaggg agagttagta tctacagaag gggctaaaca
     8641 accagtcgaa atacatgcaa aaagcatagt tgtagaaggg gaatcagata gttcgtatcc
     8701 actacaaaag aagagacata cgcttgaata tttaagaacg atagcacatt taagaccaag
     8761 aagtaatact ttttcagctg tatttagagt aagatcaata gctgcctatg caatacacaa
     8821 attcttccaa gaaagaaact ttgtatatgc acattctcca atcataacag gtagtgactg
     8881 tgaaggtgca ggagagatgt ttagaataac aactatggat ttaaatgata ttccaaaaac
     8941 tgaagatggc aaaatagact atactcaaga tttctttgga aaagaggcta atttaacagt
     9001 tagtggtcaa ttaaatgccg agataatggc actttctttt agaaacgttt atacttttgg
     9061 acctacattt agagctgaaa actcttatac aggaagacat gcttcagaat tttggatgat
     9121 agagccagaa atagtttttg cagaccttga agataacatg gaacttgcag aagatatgat
     9181 aaaatatgtt ataagctatg tattagaaaa tgctcctgaa gaaatggaat tttttaatag
     9241 ttttatagat aaaggattgt tagaaagatt aaataagata gtaaactctg agtttattag
     9301 aataacgtat actaaagcag tggaattatt aattgaatct gggcatgaat ttgagtatcc
     9361 tgttgagtgg ggatgtgacc ttcaaacaga gcatgaaaga tatataacgg agcaaatata
     9421 taattgtcca gtgtttgtta cagattatcc aaaagatata aaagctttct atatgagaat
     9481 gaatgaagat ggtaaaactg ttagagcaat ggatttacta gttcctggag ttggagaaat
     9541 cgtaggaggt tctcaaagag aagaaagaga agatgtattg ttagatagaa ttaatgaaat
     9601 gggattaaga gaagaagatt attggtggta tttagaactt agaaagtttg gtactgctac
     9661 tcactctgga tttggtcttg gatttgaaag aataattatg tatatgacag gtatgtctaa
     9721 cataagagac gttatacctt tcccaagaac tcctaaaaat gctgaatttt aataattata
     9781 tataataaaa cttatataac tttaagtata aacactaaaa tgacttgcat atttatctat
     9841 tttagagata tgcaagttat ttttattgta ctataaatat ataatttgat tacttttatt
     9901 ttgcgatata atacttatag gtttatgtaa tagtatgtaa ccttttaata aaatgcaaca
     9961 caattacgtc cttgttcttt tgcagtatat agggccttat cacaattact tataaactca
    10021 tttaatgtta ttgtctttcc aattttcttt gtataaactc caatactaac agttacacat
    10081 tttaaaggaa catcatcacg ctcaaaattg caggactcta taatttttcg taaacattct
    10141 gatttaagtt tagcatctgc ctcattacag ttaaaaatac atataaaaaa ttcctcacca
    10201 ccatatcgta tagcatgttc attttcagaa cttgtaaaat ctaaaattac tttggcaata
    10261 ttttgtagac aatagtctcc cttttgatgt ccataattat cattaaattg tttaaaataa
    10321 tctatatcta tcatcattcc agttataggt tcttgatttg catggctgat taattttttt
    10381 tgtagaatat cttcaaggta cctacggttg ttcattttag taaggtcatc tgtcataact
    10441 ttgtcgttaa gtaaattatt tatatgagat atttcttcat attgttgact aattaaaagt
    10501 ttatcatagt aagtaaatac acgatttcta tatagcattg tagaaacaaa aatggcaagg
    10561 gatgttataa aaaatgtgtt gacaatatta ctaaactcat tgcctggtat agtttgaatc
    10621 ccaggtaaga ataaattaag aaacaaaaag catcctccaa aaactattac tgattctcca
    10681 aattttaata ctgagaaagc tgcagctgct aacataatat aactaaatac acttaggtca
    10741 tttccaccta actggtcaag tagagtaatt acacaacccc ataggcagaa aaaagtcaca
    10801 taaattatcc ataaatttat ataaaacgta cagcaatcct tttttttatt ccaaaggtaa
    10861 gaaaatacaa acataaagac agaagataca caaaatagtg ttacatacat ataaaaatac
    10921 cattggcgtc ttggtgtgac aaaagggcct ccttctctag ctgagattga tatcatcata
    10981 attatttgag atattactat tattatgcaa atgattttac ccgtatgata aagataattg
    11041 cagagttctt tctcaacatt gtctttgtgt tttttgtcta gaggaaatcc aaaaaatttt
    11101 tttatttttt ctaagttcat ataagcctcc attaaaaata aagcataaaa ataagtattc
    11161 ctttctatca ttagatattt ggaatacttc gtttatgatt taattatatc aaaatatatt
    11221 gtgtgtaaca atctaaaatt gtgatagata aaatttatta gataatgtcg agtaacttta
    11281 ttgattaata ctttattata attaagattt acagatagtt tactactgaa aataaagaat
    11341 agaataaatt taaattaagc ataataaaat ataaataata aagttcgcat taacaaacta
    11401 tttaaatatc aagacctgtt aaaaaacaac agcaataaac aaataaaata gataaatata
    11461 tccaattaag gtataattaa gttttatatg atatagttat atttgataat ttacaatagt
    11521 aaaacttgga gggaaaaaat gggtgaaaag aaaataaata atatgaatta ttcacataat
    11581 aattattcca aaaagacagg tgaaccaact agaaaaataa aaaatagcca tatcactctt
    11641 aaaagtaaag aagaaaaaat ttgttctagt tgcaataaag aaaataatac taaggataat
    11701 tactgtaaat tttgtggaaa tgaactttat gaaatagcat cattaagacc acttgaaaca
    11761 aaactagact tgaaatctaa aataaaagag ctttcatatc atgcaaataa aagaggtgta
    11821 tttttaacaa catttacaac catatttata ttgtttatta ttgcattgat atttaaagct
    11881 attataacta ttcaatttaa tgatattagt tatttaataa atccagcaca tataatccta
    11941 gctctcaact tgggtcaaat tagtgtatct atgtctacca tgatgggttc tgggtttata
    12001 aatgccaata taggtttgtt gatattactt ataatcccta ttttggtatt attaatatca
    12061 aacctaattt ttatgagaaa aagatgtaga gattcaaaaa ctgtattagc aaattctcta
    12121 ggagttggaa ttttttatgg attagtttta gctattttat ctatttttac taatgtaaaa
    12181 actagttcac atagtatgtt agaatatgga tatgcattag aatatagtta tgaatttttt
    12241 agtgttcttt taaatggatt tgtattaggg tttatatgta catacataac tacttataaa
    12301 aaaagttatg aaaaggaaaa tatgtattta tctctttttt caaattctat aagaacattc
    12361 atattaggtt atgttttagt attagtaata ctattggtac taactatatc tgatagtagt
    12421 tacttaaatg aactagatat gagtagttat tcaaatggat taaatttatt tactatactc
    12481 ccacaaatag ctagttatat gtgggctttt gcaaatggaa tttcagtaac cataataaac
    12541 tcaacagtat caatgtttac tttaagttct tcatctttat ttggagatac taaattaatg
    12601 ttttatgcaa tgggagcatt gtctatgtta atattattat taaatggata caagctaaga
    12661 tttaagtata atacagatag tataagacct ataatagtat ttagtatata ttatgcattt
    12721 ttgatgggaa tattggcttt atttagtaca tttatactag atagtaatat taatttcttt
    12781 aatacaacta attatggaac aactttaata atgcaattta aagtcttaca agctattgta
    12841 atttcatttg tatatagttt tgtgatatct ttaataggat ataagctaaa ttcagctgat
    12901 taaatatgat tggagggaat ttctgtggaa ggaaatacta ataataaagt agatgataaa
    12961 ttttctaagg ttaagaaaaa gtttggtagt ggaaaattta aagttgaatt atataaagaa
    13021 aaatcaaaat taaatagaga gattgatgat attcaagaaa agaaagcaaa gatattcttg
    13081 gaaatgggaa tactgacata tcaaaaaatt agagaagatt ctattaatga taatagtttt
    13141 gataaattct gtgatgagtt actagaactt gataagttaa tttatgaaaa aaatatggaa
    13201 attaatgaaa tggaaatggc agaaagtaat gtaacttgtg agtgtggtta tgttggaaat
    13261 gtaaatgata aatattgtgc tgaatgtggt aaaaaatttg aattggaaaa tgaatgtgat
    13321 gattttataa tttgtggtta ttgtgaaagt gagatagata cagaggctga attttgtcca
    13381 tgctgtggaa gaaaaattat aatggattta gaataatatt gggaaaccta tgtatagtat
    13441 acatgggttt ttttattgaa attatttaaa tggacttata acagtagtta tataaaatga
    13501 aaataaacac caaaaaaatg aaataaaatt tcttttaaat gtaaaaaaca agctaatata
    13561 taaaataaat cagtaaaaat atagatgcga gaaaaaaata tgaaaaaata ttgcaaagaa
    13621 aaagttttca tgttattatt aatacataaa tcaagaaaat aaatttcaga aacgaggtaa
    13681 tttaaaaaat gctagataag gtaaagggaa gattaatagt atcatgccaa gctttagaag
    13741 atgaacctct tcatagtcct tttataatgg ggagaatggc taaggctgct atggaaggtg
    13801 gagctgttgg aattagagct caaggagttg aagatattat tgaaataaaa aaagttactg
    13861 gacttcctgt tataggtatt ataaagagaa actatgaaga ttcagatata tatataacgc
    13921 caactaaaaa agaagttgat gaacttttaa caacagggtg tgaaatgata gcattagatg
    13981 ctaccaatag agttagacca aataatgaag acttaaaaga acttataaag tatataaaag
    14041 aaaacggtgt tctagtaatg gcagatattt caaattatga tgaggctatc aaagcacaag
    14101 agtacggtgt agattgcgtt tcaactacac tatctggata tactccatat actaaaacat
    14161 tagaaggtcc agattttgta ttaatggaaa gattagttaa agatttagaa atacctgtaa
    14221 tagctgaagg aaaggtaaat actcctcaag atttaaaaaa ggtctttgag ttgggtgttc
    14281 attcatcagt agtaggttca gcaataacaa gaccacaatt aataacagaa aaatttgtta
    14341 aagcaattga aattaattaa aaattaattt ataaattaaa aaattattat atttaactat
    14401 atttgaaaat taaaattgga ggtaaagata tgagaacaac agatatgaag ggaatttatt
    14461 cagcattatt agtttcattt gataaggaag gaaatataaa tgaaaaaggg ttaagacaaa
    14521 taattagaca caatatagat gtttgtaaag tagatggtct ttatgtagga ggaagtacag
    14581 gggaaaactt catgctttca actgatgaaa agaaaagaat atttgaaata gctaaagatg
    14641 aagtgaaaga agaaataaaa ttaatagctc aagttggttc agttaattta aaagaagctg
    14701 tagaacttgc taaatttaca actgatttag gatatgatgc aataagtgct gttacacctt
    14761 tttactataa atttgatttt gaagaaataa aacactatta taatacaata ataaattctg
    14821 tagataatag attaataata tactctatac catttttaac tggtgttgat atgagtttag
    14881 accagtttgg agaattattt gaaaatgaaa aaataatagg tgttaagttt acagcagcag
    14941 atttctactt attagagaga atgagaaaaa cattcccaaa taaattaata tttgcaggat
    15001 ttgatgaaat gatgttacca gctacagttt taggtgtaga tggggcaatt ggttctacat
    15061 tcaatgtaaa cggtgtcaga gctagacaaa tattcgaatt aactaagaat gaaaaaatat
    15121 cagaagcact tgaagtacaa catgtgacta atgatttaat aacagatata ttaggaaatg
    15181 gcttatatca aacaattaaa ttactacttg aagaacaagg tgttgaggct ggatactgta
    15241 gacaacctat gaaagaagca actgatgaaa tgaaatcaag agcaaaagaa atatacagaa
    15301 agtattttta ataaaatact tttagtatgg gaggattagt caaatggtag gatttacttg
    15361 gatagatttt gcaatactag tggtttactt attggcagtt ttatttgcag gattgttatt
    15421 ttcaaaaaag gaaatgaagg gaaaagagtt cttcaaaggt gatggaacta ttccgtggtg
    15481 ggttacatca gtatcaatat ttgccacatt attaagtcca atatcatttt tatcattagc
    15541 aggaaattct tatggtggta cttggatttt gtggtttgca caattaggta tgtttatagc
    15601 aatacctttg acaataaaat ttttcttacc tctatatagt aggttagaaa tagatacagc
    15661 atatgaatac ttagaaatga gatacgaaag caaaggtctt agagtacttg gagctttgat
    15721 gtttataata tatcaaatag gacgtatgtc tatcataatg tatcttccat caatagttct
    15781 ggctggtctt acaggaatac ctgtaaatgt actgataata gttatgggtg taatagcaat
    15841 aatttactca tatacaggtg gattaaaggc tgtcttgtgg accgatttta tacaaggaat
    15901 ggtattaata gtaggtgtta cagggacatt gttctattta atagcaagta taaatggtgg
    15961 ttttggaaca gtaatggata ctcttacaac tggacacaag ttcttagcaa gtaatgaagt
    16021 tatgtttgat aaaaatatac tatctacaag tgcatttata atatttgttg gagctggtct
    16081 taatactttt tcatcatatg tatcgagtca agacatagtt caaagattta ctacaacaac
    16141 tgatataaag caacttaata aaatgacata tggaaatggt gttttatcaa tgggacttgc
    16201 aacagtattt tatctaattg gaacttgttt atttatatac tatactcaaa acccagattt
    16261 agctcaaaca gttcaacaag accaagtatt tgcatcatat atagcttatg aattaccagt
    16321 gggtataaca ggaatactac ttgcagcgat atatgcagct tctcaatcaa ctttatcgac
    16381 agggcttaat tcagttgcta caagttggac tttagatata caaactatca taacaaaaga
    16441 tataagtatg gaaaagcaaa ctaagatagc acaatatata tcattaggtg taggtatact
    16501 ttctatagct gttgcaatag tattagcaaa tggagaaata aagtcagcat atgaatggtt
    16561 taatagtttt atggggctag tactaggtgt tttagcagga atatttgtac ttggtgcatt
    16621 ttgtaaaaaa gcgactaaaa tgggagcata tgttggattc atagtatcag caattttagt
    16681 tgtttattta aaataccgta tgccagaagt aacttcttgg gcatattctc taataacaat
    16741 cacgacttct gtagtggtag gtacaatagt tagtgcaata gaagctaaag ttaaagcaaa
    16801 agtatcttta ccaaaagctg agactactgt ttattatgaa aaataatatt taaatgataa
    16861 attgtcttat agagtgatta gataaataat ttagttactc tataagattg tataatatac
    16921 tttgtatata aaagtataaa aatagacttt ataattatat agggagatag tgcttatgat
    16981 atttggaaat ataaatcata gtaagacata ttcaacattg catgaagatt tacttagatg
    17041 ttttgaatat gctaaagata attcattaat agattatgaa aaaggtactt atacaataga
    17101 tggtgatgat atttttgtga atattgtaga gtataaaact tgtgaaaaag aagatagatt
    17161 ctgggaagct cataagaagt atatagatgt tcatttgatg cttgatggat gtgaacgaat
    17221 agatataaat tttatagaaa atttagaaca aaaaatatat gaagaaaagg gcgatttctt
    17281 gcctcttgat ggtaaaaata atggatacat ggaacttaga aaaggtgatt ttttagtttg
    17341 ttatccggaa gatgctcata tgacaggaat aaaagtttta gaaaaagaaa atatcaaaaa
    17401 agctattttt aaggttttgg ttagataatg ataatttata taaccactag ggctgaaaat
    17461 agtgatttaa ctttcagcga ttagtgagac ttcgtaaatt ttagttagat tactattttc
    17521 agccttagtt ttttatgaga aaattgaaaa taattaaaag cttaaaattt tgtaaaggag
    17581 ttaacttatg gaaaatatag atgtattctt attaatagga caaagcaatg ctagaggatt
    17641 gggaaatcca aaagagagca tcattccaaa tgaaaattgt tttgaatatt tgagtactga
    17701 tgaaattata aatatgagat gtgagctaga gacttcagaa ggtgatggta ctatagcacc
    17761 tgcattttca aatgaatgga ataagcttac tggaaataaa gtttgtttta ttcacaatgc
    17821 aaaagatggt tcaagaataa aaaactggaa tcatgataat aactggtttc taaatgacac
    17881 tatagaaaaa tttaatacag gctgtactac cttaagtaaa cattataata tagaaaataa
    17941 atacgttatt tggattcaag gtgaaagtga tgcaaaatat ggtagtgatg tattgtacta
    18001 taaagaaagt ctaaaaaaaa ttgcgtatag gcttaaagaa gaatgtatga ttgataaaat
    18061 gtttgtaagt ttaactggtt attggcttgg agaagatgaa tattttatta gaacaagacg
    18121 aattgcagca gcacaggagt cggcttgtag tgaatgtgat atattatgtg taggaagcaa
    18181 aattgctatg cagtttcatg acagaggatt aactattgat gatgttcatt acactcaaga
    18241 aggtcttaat atgttaggag aggacttatg taaaaatatt tataagtatc atataaccaa
    18301 agaaaaaagt gtattaagtg atactataga cttatcagaa gcaaggaaat atatctgtga
    18361 attggaaaag ataagtaaaa gatttgtgta atataaaatt ttaaatagag ttgttaattt
    18421 ataaaaataa tttgtatgga gatatgttat gaaaaattac gtttgtatag atgttggggg
    18481 tacttcaata aaatatggtt ttattagaga agatggattt ataattgata aatcaagtct
    18541 tgatactgaa gcaaaggaaa aaggtggaga aggaatatta gccaaaataa aagatatagt
    18601 aaaaaaatat atagaggaaa atgaaataag tggtatatgt atatcaactg caggtatggt
    18661 tgacccagtt gaaggtaaaa tactatttgc attagaagaa ttaattccaa actataaggg
    18721 catgcaatta aaaaaagaag tagaaaaaga gtttaatata aaatgtgaag ttgaaaatga
    18781 tgttaattgt gctggacttg gtgaaatgtg gcttggagca ggtaaagatg caacatcttc
    18841 tatatgttta acaataggta ctggaattgg tggatgtatt ataataaata ataaactgat
    18901 aaatgggttt agtaatagtg ctggtgaagt aggatatatg aatgtaaatg gaagttcttt
    18961 tcaagaattg gcatctacta gcagtctaat taaaaaagta gcaaaaataa aaaatttgaa
    19021 tgaaaatgac ttaaatggaa aaataatttt tgatttagca aagaataatg atgaagattg
    19081 tttaaaagaa ctcgataata tgataaaatc attagcagtt ggaatcgcaa atatatgtta
    19141 tgtaataaat ccagaagtgg taattttagg tggtgggatt atggcacaag aaaagttcct
    19201 aaaaccaaaa atagacaaag cattaaagga ggttcttata gagagagttt acaaaaacac
    19261 taatatagaa tttgcaaaga gacaaaatga tgcaggaatg cttggagcat tatataattt
    19321 tttaaacaaa atataaagaa tagaagggtt tttaatgagt attttagaac aattggaatc
    19381 accaactttt aaagtcacaa aatcagataa attattaata gcttatataa aagaaaatat
    19441 agatgatgta ttttataaac caatatcaca aatagctaaa gagagcaata ttggtgaagc
    19501 aactataact aggtttgtaa aaaaaatgaa ttttaatgga ttacaggatt ttaaagttac
    19561 tttagcacaa gaaatatcaa ctatcaataa aaaaaatatt ataaataaaa atatacaaaa
    19621 tgatgagcca gctttggata cagcaaaaaa acttttaagt tcaaatgtaa ccactttaga
    19681 gaacacagta gagataatca atagtaagga tgtacatgac tgcgcaaggc ttataataaa
    19741 tgcaaagaaa gtttacttca taggtattgg atattctggt ataatagcac aggattcaaa
    19801 ctataaattt atgagaatag gtcttaattg tgtaagtttt gacagtagtc atacaatgat
    19861 aatgatgtct tccataatgg aagaaggaga tttaataatt gcaatttcac attctggtga
    19921 aacagaagag attataaaaa ctgtaaagct tgcaagagcc aataatgcta aaattatatc
    19981 aattactgaa aataaaaatt ctgaattaaa ggatatttca gatgtacact tatcttatgt
    20041 atcgggagaa acagtactgg aaactggttc aatatcttct aaattagcac aatttttcat
    20101 tattgattta gtatatacac aggtagtaaa agaactttct aatgaagcta ttgaaaggaa
    20161 aattaaaact acaaatgcta taaaattgtt taaaaatgaa taaaataaga aatttgtaat
    20221 gttttataga gctctcttaa aaatttagga atggagagat attacatgtc taaattaaaa
    20281 gattataata ttgataaagt aataattttt aataatttaa gtactaaaac gaagaatcaa
    20341 cttaaagaaa aagttaaact aaaaagatta caaaaaaaag aaattttatt ttatgaaaaa
    20401 gatagcttag acagtgttta tatactttta gaaggaaagg tatctatttt taagataagt
    20461 gaaaatggag agagaaaagt aattttcata ttaaatagtg gggaagtcat aaatgatatt
    20521 acacttgacg cttctaaaaa ctctactgtt ggctgtgaag catttgaaaa ttcaattgta
    20581 gcttattata gtattgaaga atttttagaa attatgcaaa atgattttca acttacaaag
    20641 gatattattt cttatatgga aagaagaata agacgtttat atagacagtt gaaaaattct
    20701 atatccataa aagtagataa aaaacttgca gcaaaattat ataggttaag tagagaattt
    20761 ggagtttgct gtggagaatg gactttacta aatgtaaata ttacagttac atatttagct
    20821 gatatgcttg gctgtaaaag ggagactgtt tccagaatga taaaggtatt gcaaaaagaa
    20881 gaacttatta aaattgacaa taaaggtttt tatgttaaag aaactgaatt atcaaggtat
    20941 tttaaaaata attaattatg attaagtaag agtattatta gaattttaat taaataaaaa
    21001 tattattaag agaatctatt tatagattct tttttattgt ctaatttatt aatttttatt
    21061 ttaccctatt gaattgtata aaaaaacaaa taagattctt ttttattcaa aaaattgagt
    21121 agatagtagt tttattgtac ttaatgattg tatttaagtg attagatttg aaatcgaata
    21181 atgtagataa taaaaaaata ttaacagaac ttaataaact ccattaatat tttttttatt
    21241 atttttgaaa ctgtgataat tatcacggaa gcatagaaaa taaagtgtta agatttaaac
    21301 aagatagcaa gtaagtaaaa ctaaaatata agaaaggtga taaaaatgaa actaaaatta
    21361 gattcatcta agttcaatga aggtctgaat tatctaaaaa aagactacaa gatatttgca
    21421 ccagttttaa tcccatttaa aggtactttt tcagatactg atgttataag atacaaggag
    21481 gtaaacgctt ttgaagaaat ggaatttgct aagaaagcaa acttttcacc aaaagaagtt
    21541 gtacttccca taaatcaagt attgttttat tttactgaaa aagagtttaa ggaaagcgat
    21601 ttagacaaca agaaaatttt aattttctta agagcttgtg acataaatgg tataaaaaga
    21661 cttgatgaaa tatatctaaa taatggtgaa gaaaaagatt atttttataa aaatatcaga
    21721 gataaagtaa agtttgcact tgtagggtgt aaggaaagtt ttagaaactg tttttgtgtg
    21781 agcatggatt ctaacaaaac tgataattat tcaattggat taaatataga aggagataca
    21841 ctgtacttag atataaagga tagtgaattt gaagtattta atggagaagc aactgaattt
    21901 aatgttgatt atgtaactga taatttaata tctgtagatg tgccagagaa tattgattca
    21961 aatgaaatga taggaaattc aatatgggat gaatatgata caagatgtat aggatgtggt
    22021 agatgtaatt ttgtatgtcc aacatgttca tgttttacaa tgcaggatat tttctataag
    22081 gaaaacgaaa atgtaggtga gagaagaagg gtttgggctt cttgtcaagt agatggatat
    22141 acagatatag caggtggaaa ttcttttaga aaaaaacaag gcgaaagaat gagatttaaa
    22201 actatgcata aaatacatga ttttaaaaaa agattcggat atcatatgtg tgttggctgt
    22261 ggaagatgtg atgatgcctg tccgcaatac atatcatttt caaagtgtat agaaaaaata
    22321 aatgatttag taattagtaa ggaggaagta taaatgaacc catatatacc agtaagtgca
    22381 aaaatactag atatagttaa acatactgat aaagaatgga cttttagagt aaactgcaat
    22441 acaaaaggtg tattgcctgg aaagttttat gagatatcta tacctaaata cggtgaaagt
    22501 ccaatatcag tatcaggata tggagaggat tatattgact ttacaataag aaatgtagga
    22561 aaagtaacta gcgagttgtt taattataaa gaaggagatt ctttttttat aagaggtcct
    22621 tatggaaatg gatttgatgt atccctttat gaaggaagag aaattgtagt agtggcagga
    22681 ggaagtgcat tagcccctgt aagaggaata gttgaatatt tttataataa taaagaaaaa
    22741 tgcgaaaagt ttaaattaat agtaggattt aaatcaccaa aagatatttt atttgcagat
    22801 gatttaaaga gatggagtaa aaaacttgat attttagtta ctgtagatgg agcagaggaa
    22861 ggatatagtg gtaatgtagg attagtaaca aaatacatac cagaattgga tatgaaagat
    22921 ataaacaata cttctatagt tgtagttgga cctccaatga tgatgaaatt tacagtagaa
    22981 gaatttttaa aaagagattt agatgaaaag aacatttggg tttcttatga aagaaaaatg
    23041 tgttgtggaa taggtaaatg tggacattgt aaaatggatg atacttacat atgtttagat
    23101 ggaccagtat ttgattattc atatgctaaa aatcttattg attagggggt gaagtttgtg
    23161 ataagagatt taaataccaa aaaagtaatg aaaaatgctt atagaattac aaaaacaaaa
    23221 tatgagactt ctttaagagt tagagtacct ggaggtctta ttgaccctga gagtttagct
    23281 gtagtttcta aaattgcaag tgagtacggc aatggacagg tgcacataac tacaagacag
    23341 gggtttgaaa tattaggaat aaatatggaa gatatggaag aaataaataa aattatacaa
    23401 cctgttattg aaaaaatgaa tataaatcaa agtgagaaaa acgcaggtta tccagcagca
    23461 ggtacaagaa atatagcagc ttgtatagga aataaagtct gtccaaaggc tcaatataat
    23521 acaactgaat ttgctaaaag aatagaaaaa gctatatttc caaatgattt acattttaaa
    23581 gtggctttaa ctggttgtcc aaatgattgt ataaaagcta gaatgaatga ctttggaatt
    23641 attggtatgg ctttaccaat atatgaaaag gatagatgtg taaattgtgg agcatgtgta
    23701 aaaaaatgtt ctaagatatc tgttggagca ttaaaaacag aaaataataa ggtggtaaga
    23761 gataaagata agtgtatagg ctgtggagag tgtgtgctaa attgcccaac aaatgcatgg
    23821 actagagatg agaaaaaata ctatagatta gctataatgg gtagaacagg aaagaaaaac
    23881 cctagactag cagaagattt tcttttatgg gtagatgagg acagcataat aaagataata
    23941 cttaatactt atagatatgt agaaaagtat atagataaag atgcaccagg aggaaaagaa
    24001 catataggat atataattga tagaacagga tttatggaat ttaaaaaatg ggcacttgaa
    24061 ggtgtagagc ttccagaaat aactaaaatg tacgaaaaca tatactggag tggaattaaa
    24121 tatctataaa ttgagtaaaa catatatttg aataaattaa aatttaatag aaggaagagg
    24181 gaattatgca taaagaaact ttggataaat taactaatgc agctataaat aagataaatt
    24241 tattaaacac aagtaaagta aaatatttgg tatcttctgc gtttgcagga ctttatgtag
    24301 gtataggtat acttttgata tttactattg gaggactttt gactgatgca ggttcaccta
    24361 tgactaagat agtaatgggg ttatcatttg caatagcact aagtttggtt ataatgacgg
    24421 gaacagagtt atttactgga aacaatatgg ttatgtctgc tggtatgtta aataaaggtg
    24481 taagtataaa agatacttct aaaatatggg catacagttg ggtaggtaat ttaatcggag
    24541 ctttggtttt aggcattata tttgtaggaa ctggtctaat agacaaagga cctgtagctg
    24601 aattttttgc aaatacagca gctagtaaag catccatgcc atttacagct cttttcttta
    24661 gagggatttt atgtaatatt ctagtatgtg tatcagtgtt gtgttcgttt agaactaata
    24721 gtgatactgc aaaaataatt atgatattct tatgtttatt tgcttttata acatcaggct
    24781 ttgagcatag tgtagcaaat atgacaattt atagtgtttc attattttca ccaacaataa
    24841 atacagttac tattggagga gctatttata atttagtagc tgtaacactt ggaaatattg
    24901 ttggaggagc tttatttatg ggtcttggaa cttatatatt aggtaaagaa aagcttaatt
    24961 aaatttattg tataaattat aactctcttg ataaatgcat ttttagtatt gttgagagag
    25021 ttatttttat atttttgaaa aaatatttga aacaaaaaaa atatgggagc atacgaaaat
    25081 atatcggtta tatatataaa aaatacgttt atatatgaat tatatagttc taaatataaa
    25141 aaaagttaaa gtcctaccgt aaaaaagcgc attttgaata agataacaaa tatgataaaa
    25201 ttggtcttgt tgaaattttt aggggggata tgatgacaaa gaaactagta atatcaaaaa
    25261 caaagttgtt tatttttata atagcattta tttctatatt tatatattta tttggaagta
    25321 aaaatacact tataggtgta ggtatagtaa cagctatgct aacgctcttg gaaagagatt
    25381 taactatttc tccaattaaa aatttactga agtatttagc aataaatata atcttaggaa
    25441 tactatcatt ttttgcagta caaaatatgt atttaggagt tttattaaat tttatagcat
    25501 tatttataat agggtatgta tttagttatg acttaaaaag agcagtatat gtaccctttg
    25561 gtctaatgta tatatttatg gtaagtatac ctgtaggaaa aagtgaattt cctatgagat
    25621 tgtcggcttt agctgttgga gcagttataa taatgattgc tcaatttgtt atgaatagaa
    25681 ataggatgaa aaatgtcgga gataaagaac tgatatctat atgtgatgaa ttattagaaa
    25741 aaattagtct tttaaaaaat actattaatg atgatagttc tataattaaa tctagtatga
    25801 gaaaaataga tagctgtaat tatagaataa attctatatc taaaaatttg aaaatggtta
    25861 tttttgataa tagaaaagat gacttttata tcagtattag aggtatagac ataatgaata
    25921 ttttattttc attagaaaga ataagtttaa tcctagaaag atacaaaaag gatagtaaag
    25981 aatttgaaga tgaagatata aaaaatattt tagaagaaag tagcataaat agtaaatcag
    26041 atgttctagt tgtagcaacg aaagaaataa actatattaa gatgtgttta gaaaataaag
    26101 ataccataac tgataaagag atattaggat ttagagatta tgttattgct caggatacta
    26161 aaaatataaa tttaaaagaa atttatagtg ttttagaaaa tttatatgag tttttagtag
    26221 attataaaaa agtaaaatca agagacgaaa agaaagctga aagaaaatca aagatacctc
    26281 atgaatttaa acgactatca atatataaga aaaactttaa tttaaattct ataagatttt
    26341 cttatgcagt aaagattgct ttagctacag ctgtagcggg ttttattatg gattatttcc
    26401 atttaagaga tggaagatgg ataatgttaa ctgtcttttc attaacacaa ccttacgcag
    26461 aaaattgtat acaaaggtct agaaaaagaa tagaaggtac atttatagga gctgtaatat
    26521 ttattgtatt attttcaata ataaaagata gtacattaag gtcgttaata gttcttttag
    26581 cagggtatat aaactcttat gtagttgatt atagaaaatt aatggtatgt gtaactgttt
    26641 cagctcttgg ttcagcagta gttatgggag acccaaatgt tttaaccata agcaggattt
    26701 catatgtagc attaggagca attattgcat taatagtaaa taagtttata ttaccatatg
    26761 atgctaaaac aggctatcaa catgttatag aaatgtataa aggaatagtt aaaaatataa
    26821 ttgatgaagt caataagtct atagaaaatg tagctgatgt ttactatata aaaaatttat
    26881 tattgatacc atcacttatt gaagatagac ttatgttgat aaatgctata tataaagata
    26941 aacatcaaga ggatttttta gaaaatcaga aattactaat aagtaatatg tataatctat
    27001 atataaatgt taataaaaat aaaataaaag atgaagatgt tgaaaaaata ttgagagata
    27061 ctaattatat ttcaaattac aatgtagata agtatgatga aggaagaagt gtaattttag
    27121 agagtattat aaatactaaa agtctaggtg acaagataat atgtctaaac ttactgcaaa
    27181 ctctaaatgg tgtcaaagaa atgtatagaa taagtaatat aactaaagtt tcaataaaag
    27241 aagcagctta gatattaaat tatagaatag ccatatattt aaaataaagt atatggctat
    27301 ttgttttata aaatactaaa agaaaataat atataaaaaa caaaaaacat atatttatga
    27361 attttatatg aaaatagtta aaatattgat ttttttcatt ggttgaaaaa acaatttact
    27421 taggataaac tataatagta ttcaaatatt atgggggtta gatttatgag taaagatgta
    27481 aaggtaaagc gtaataagaa atatgataca tttagtataa ctatggaact tgagagacct
    27541 ttactttatg atgaggttga gaacaaagat gataaaaata ataatagaaa atttaacata
    27601 aagaataaga tatttaaggg aataggtata ctatttgtat tgattttgct tggctttttc
    27661 atatggataa ataaaacata tgaacctcaa aagctggcaa aagaagctct agtcagcaat
    27721 agtaaagttg aagtaactgt aaatgaaaac atttcattta caccaaaagg aagaaaagtt
    27781 tctaaaggtt taattttgta tccaggagct aaagtagaaa tagaatctta tgctccactt
    27841 gcaagaaaaa tagcagaaag tggatatgaa gttgtaatcg taaagatgcc acttaatcta
    27901 gctatacttg gaactaataa ggcacagaaa gttatggatt cttacaacaa catagaacat
    27961 tgggtaatag gaggtcattc attaggagga gttgcagcat caaattttgc acgtgataat
    28021 aaattaattg aaggcgttgt atttttagct tcttatccaa tgggtgatga gttgaaagaa
    28081 ttaggaaaaa aagttatatc tatatggggg agcaaagatg gagtagtcaa ttttaaaagt
    28141 cttgtagaat caaaacaaaa acttcctgat gatacaactt atgttgagat tgaaggagga
    28201 aatcatgcac aatttggaga ttatggaaaa caaaagggag ataatgatgc tattataagt
    28261 caagaaaaac aacttaatat tactgccaat agtatcatta aatttttaaa gaatatatct
    28321 taaactaaaa tttaaaaaat ataattttat aagttattat ttaaagtaaa tattaataat
    28381 ataatagaat gaatatttta ttacaagggg gattttaata tggaatacga tatgccactt
    28441 tacagaccac caagtgaggc ttatagtctt ataatacaag tcacactagg atgttctcat
    28501 aacaaatgta cgttttgtag tatgtacaaa tctaaaaaat ttaaaataaa gccactagaa
    28561 gtaataaaaa atgaaattga tatatttaga agatattata agcatgtaga aagaatattc
    28621 ttagcagatg gagatgcatt gataatacca atggagaaat taagagatat tattttatat
    28681 ataaaagaag tttttccaga gtgtgaaaga attactatgt acggctctcc taaatctata
    28741 gagaaaaaat ctgatgatga acttaaagaa ttaagaaaac ttggtgttaa aatgatttat
    28801 ctagggcttg aaagtggaag caatgaagta ttagaagata ttaagaaagg ttttagtagt
    28861 gaacaattaa taaaagttgg tagaaaagtt aaaaaaagtg ggattaaatt atcagccact
    28921 gtaatagcag gtcttggagg aactaaaaaa acacatcagc atgcagttga tacaggaaaa
    28981 atgctaggag caatttcacc agattatgtg ggtgtactta gtttaatggt agaacctaat
    29041 actgaacttt acgatttact taaggcagga gagtttacaa tactagagga taaggctgtg
    29101 ttacaagaaa ttaaagagat gataaagaat atagatgcta atgaaaaaat tgtatttaga
    29161 agtaatcatg catcaaatta tgctaattta aaaggtgtat tacctgatga taaacaacgt
    29221 ctaattgatg aaattgatta ctatctaagt aaccaaaagc taaaaagaga agaatataga
    29281 agactatagt ttttgatata tcaatctata ctgataggta aatactaaga ttatttagat
    29341 acaaaaaatc atgctacatt aatagttgct tactattgat gtagcatgat tttttattaa
    29401 aaaacaaaat ggtatattca tatataatat atcaataata atgaaaatgt gaactagttt
    29461 aatagaattt tacctattat aataaaaaca ggaatttaaa taataaaaag taaagtaact
    29521 ttttattaag taactttact ttttatttta tttaatgttg tattaaattt atatatatta
    29581 aaataatata caaattttga aaaagctctt ataaaatgat tattaaagta aagtttaata
    29641 taaataaatt ataaaatatt aaactaattt atcaatattt cctgattgaa tatgcttaat
    29701 gtttgattga atttttttat atggccaatc ccaccattta atttctaata attttgaaat
    29761 tgtatcatta ttaaatctct tttttataat ttttgcaggt actcctccaa caatagaata
    29821 cggtggaacg tcattagtaa ctactgctct tgttccaata attgcaccat caccaatatt
    29881 tacacctgac ataattatag aatcataacc tatccacaca tcatttccaa ttataatgtt
    29941 acccttattg tcccaagcgt ccgttatatg gttgatatcg agtttccatt cttcataaaa
    30001 gatgggaaaa gtatatgtgg attttgattt cattgagtga tttccactag tcattagaaa
    30061 ttttgcatta catgctattg agcaaaactt accaattatt aatttatcat tgtttatagg
    30121 gtaatgatac aatacattgt ttttctcaaa atctcttggg tcattataaa agtcattata
    30181 tattgtgtaa tctccaactt ctatattttc ccttgttatt acatttttaa gatatacagt
    30241 ttgataatca ttacttcttg gatatacctt atttgaactt ggaatagtca tatttaaatc
    30301 tctcctttaa tatatattat gtttttgact attccactac tacaatacat ctcttcacag
    30361 aatcactcct tgttaagaat cttcataaga taatggcgtc cttttttagt gttaagtcgg
    30421 atattctttc ttagtccatt ctttttagcg tataactgac aaactgtcat tttcttacca
    30481 atagtgtcaa tgctatcatc aaggtcattt tgtattgctt tttccttatc ccttaatgat
    30541 atatcatcac gttttccctt tgggggttta tcagtaggta caagtttcca agagtaaaca
    30601 aattgtggtt taccaaatga atatacatac ttatatgcgt atcttccatc ttttctctgg
    30661 ctctctccag ttcttaaaat tctatcttta ttatctcgtc ttttttcagt tgacatgata
    30721 agaagctcct ctcaataacc gaattgagct tgatacgtca tatgaatatt ataacatata
    30781 aggctcaatt tcattagata acgtcaagtg tatcaacgat tttctcaaat tgttttctct
    30841 ttatttgaat gcgattgcta ttcataatga cccagccaga atcaaggttt tcatcagcac
    30901 gtttacgtaa ttttttctct ccaatacgaa agtattttga cgcttcttca atcgtcaagg
    30961 tatatttttc ccaaataggt acatcagtat tgttcatata atgtatcact cctttctatg
    31021 ttcgtagttc agaagtagat agatggcttt gataagctcc attggtattt caaccaatcc
    31081 cattcttatg gacagaaccg tgtcatacag gtgtatcatt atactgtggt acaggttacg
    31141 gcaaaacaac cgttccaaag gttattcaca aatcactata tagtagctct cttgattaag
    31201 gtcatggcgt atagtatttg ttggctatct gtatcacaaa cgtatctatc tactttattc
    31261 agttgtcaaa gaacagtcgg cattgatttg cctataaaaa atcacaatag cttgtgggct
    31321 tttatagaca aataattagt gattctccat gtaccaaata gcttgataca tggagagagg
    31381 gcgagattaa gacaaattaa atctcaaaat agcagtgatt agttttgttc ctagcattcg
    31441 ctttgtttct tcttctacat gaatataggg atttccgtat tcatcaaata aagttttctg
    31501 tgaaagacga atgatatagt gttcaaaatg tttaagtatt acgtttattg catttacatc
    31561 gccatgtaca gcaagtaaaa taattgtaaa aggtaatact tctttagtag gtttcatttc
    31621 aatgttcctg catgagttct ttcaactctt ttagtgcatt tgttttgtga taatgtatgg
    31681 tattttctgc taaatccatc aatgttgcta tgtcagcatt tgtcatgttg aaaaagaatg
    31741 aaagtagaat tatatcttgt tttctttttg taagttttcc gattgcttgc gccattaata
    31801 catcttcaat tcgtatgttg tagtcgtaag aaaccataca gatgtagtta gaatcataat
    31861 catctaaaat actcaattta cttaattctg caagtgacaa agattcgaga gataccaaat
    31921 aatcatttct gcgtttattt tcgtcataaa tatctctagc atagttacgc aaaactgttt
    31981 tacagaaact gtcgaattga tgttcaattg tcttttcatc aaccataaga tttcaccctc
    32041 tttccatcgc aaggagttaa ataaccttgc ttactcctat cacggtggga gggcgttaaa
    32101 tcttcgataa atttcaaaaa aaagagaaaa aaatacacac tctgcctata gggcaaaaat
    32161 gtgtattctt taaaacgtat ttaatttata ttggttgtaa gccaccacca tattgatgta
    32221 tggaaatatg cattggctag cttttcataa aaatacaaag atgcataaga aattaataga
    32281 ggggaaaaac ttattctgtt attaaaaagt aggttaattc taataaatgc tattgcggtc
    32341 gaattaaact atatacatgg caatcaatca tgtttctatt ctttattatg aattgtgaca
    32401 gtattcttca atcttaaagc cacatttttc caatacttta cttgactctc tattgtagga
    32461 atatacatta gcatgaattt tgttaaggtt gtatttttca aaggcaattt tgcatatttc
    32521 ttttactgca tttgttgcta tccctttgcc tcaatagttc ctagcaagcc agtaacctaa
    32581 ttcagcattt ttattaatag aggtatcttc ttcaaatgtt aggctgatac ttccaatagc
    32641 cctttcttga taaaaaatag catagctaag ttgtttaaca tctgaagttg ccaaacaaaa
    32701 actaacaaaa tctctagcgt tttgctccct ataagggtgg gggaagttgt cacgaagatt
    32761 ctttgcaatt tctttatcat tcgcaaactc aactaaatcg gtaatataag cataattcca
    32821 ctctataagt tccatttttc ttctcctttt atgaaacagc tacaagaaat ctttctaagc
    32881 caataccact tatcaaacag cgttctcttt tatttccaag catttgataa gtccagtcaa
    32941 caaatccacc gtcaactatt tcaacggttt catttccttg tttgaccgat aatttgaaat
    33001 tgataccttt ataataatta ttatcaacat catcattatg aattgataac tctatattag
    33061 gaaaaataag tttgatagtt tcaaccattc tgtcgaaaaa tccgtcatta tctttgtatc
    33121 cgtttctttt gcgtagaata atagagaaac gaacattttc tatttcactt aatatatctt
    33181 tataatagtt taagtgcttt tctaacaaca ttttttcaca agtgtaagac cctgtatcta
    33241 taccagatga aaccatacaa tataagccaa aatgtgaata taaaccttta cctacaaaat
    33301 tttgtgctct tattacccta gcagtagtag ccatgtggat aggtatggta ttattttctt
    33361 cttttctttt taatttatca gcaataatta ttgccaacat atttgagggg tctgcaagtg
    33421 tttctgtccc tcgtagagca cttactacgt tatattgatc tacggagcca aaaacgctac
    33481 agctacctaa tggggcagag ggagaaagca taatcgtctt gatatccata ttgaatgctt
    33541 ttctcaataa ttttgattcc aaagcatgaa tttcttctgg atctataccg ctagggatag
    33601 taaatctatt tagttggtat gactttagaa tatcagttgc agttaaagta tttgcttgtc
    33661 tatcaaacac ttctaataga agtgagttca aatctgattt tgatagagct gataacttat
    33721 caactatatt cttatcccca attttatttg taattctact taaaatatca ctcatagtta
    33781 tcctccatac tgttactttc aaaataatta tagaattgtt acaacaacta atctaggtca
    33841 tttgaccaaa aatgaaaaaa cactgaatat ttactattca atattttttt actttgggtt
    33901 tatttgatta aatcttgaaa atactgtaat gcaacccttt cagcttcaac ctttcggaca
    33961 ataggacttt gtgataattc ctctcttaac tcaagataca ggttgatagt agcctgcaat
    34021 gcattaacac agcttttata ttcatggtta gcaaccgtct tttctaatgc ttcaatatat
    34081 tggggtgcgt ccaattcaat ttttctaact ccacgaggta atttacctaa gagaagctgt
    34141 attaatgggg caagtactga ttgtcttaaa aaagataaaa aatcaattgt ttcaaatagt
    34201 tctctacgtc caatcttagt gcaagcgtaa tgaacccaaa tccaaaatct atcttcaatc
    34261 cactgtaagt ctggagttgg gaagtatgct tcttttttag aataaatttc tgttatgcag
    34321 ttgttttctt catagagaat agctgaatct tcaaccctat ctagtaaacc atctaaggtt
    34381 gtaaacttaa aatcaacatg aagaacaggg gaatcataga gggaaattat caatcgaggt
    34441 tctccaacgt gttcgccagt aaaagcagaa actaatgttc caaactgttc cacaataagt
    34501 aatctctctt cgataacttc ttcataggat ttatcatctg ctacaatcag aaaatccaaa
    34561 tcagaatatt catctaacga ttttgtgata taagaactgc taattgcaag tcctattatc
    34621 ctactatctc tttttgaaaa ttctaatacg ttttgtatca ttttctgttg tgttttagtc
    34681 ataatataac acctctcact gtcttttatt agctatcaat ccaacataat tatgcatagg
    34741 agtattatat aatgaagaaa taaaaaaaaa taggtcactt gacccgaaat aaaaaagcat
    34801 tgaataatta ttattcaata cttttttgaa attatactta tgttgtagga agattcttta
    34861 atacctctcg ctgattaatt acactaaatc ttttgttttc ataagcaatt agatgttctt
    34921 gtacacattc atttatagca cgattaatgc ttctaattgg agcgtttact tcgctagcaa
    34981 gctgtttttt ggtaagcaga tttaattcac ttctataata gtgtaaggat atacacctca
    35041 gaagtcgttc tttaacactt aaagatgata attcttcaat taattcagca tttacaacta
    35101 atttactaga tatttctcga atcagaaatt ttgtagcttc aaaatctccc cttaaccagt
    35161 ttaaaaaatc atctctatga agtttatata cattacaatc tgtgaaagcg acaatttcaa
    35221 cgggtttttt cccatcatta aattgttcca tttctccaaa aaaactacca cttctataaa
    35281 gatgaatcgt tgagatgttt cctttcacat ttaagatgaa tgcttctgca ataccgtcaa
    35341 tcataagaat tacatattca ttttcttgct cagcaaaaag aatagtctct ttctttttat
    35401 acgttttttt aacaagcttc tttttaatat cttcattcat aaaatcaatt aaatgcatat
    35461 tcatccctcc ttaccaaatc tttgattaaa ttatatcatc tttcaattag ttaggtaaga
    35521 tagtaaaaat atatttacat agaaactatt ccattattat tttccagttg tcatttttct
    35581 gcaaaaactt atcactgtca cgactggaga taccagtaag gaatgttagg atatcaatcg
    35641 ctaaactttc agaatccttt ttacggctca aaatgacgta agggtcaagc aatcctttgt
    35701 tttcatcatt actggttaaa ttgacaatgt ttatctcatg ggctatttct ggtagcgttt
    35761 ctttccattt gccgcgttct gctttagggt caactatgac cgcctgtccg ccgaatagta
    35821 ccgcatagta aacaagcata ttgttactga ataatttacc accacccaat gaaccgataa
    35881 acgcagacgc taacgcattg gtaatagaac cctttacccc ttgactagca agggcaggtt
    35941 ttagatagac attctttcca gtgtccagat tgtagccaag atagatatcc tcatgttcgc
    36001 caagggtttg tgtcgctcca aaaccaagtc cagccaaaaa atccgaagtg acatattgaa
    36061 tataatcatt gatgtaacgt ttgctgacag gaataaattc gccatgcaat cccaacatat
    36121 ccccaaaggg acgcacgagc ttgattgata agtcgtcgta aaagtctttg acttcatcac
    36181 aacgcctttt tagctcgtca agattctttg tagatacacg gacaacatag ctaagtttat
    36241 acatagattc tttacagtta aaagtctgtt tttaaaaaaa tgtataaatt ataaatcaaa
    36301 atatagatac tatcaatgac ccactaggtg caaaaagcat tgatatggtt aaattatcag
    36361 acgctaaaag ctgggctatc cgaatgagtg aagatgggtg tgcttataaa tccattgaca
    36421 attataagcg ctcactgaaa gcgtcgtttt tcatggcaat tcaagacgac tgtattagaa
    36481 agaatccatt taatttttag ttaagtgatg ttttggaaga tacaacagaa ccaaaaatcg
    36541 ctctaacacc agaacaggaa atgggcttat tatcctttat ggggagcgat aagacttatt
    36601 gtaaatatta tgatgatgtt gttatcctct tagaaacagg actacgcatt tctgaattat
    36661 gcggtttgac tttagaattg gatatgaaaa ataaagccat tatggtagac catcaattgt
    36721 tgagtgatac taagattggc tattatgtag aagttccaaa gaccacacag ggtaagcgag
    36781 aaattccaat gactgaaaga gcttatcaat catttgaacg tatcgtggaa cggcgtaaga
    36841 acgctaaagc agaaccaatc attgttgatg gttaccagaa cttcctattt cttaaacaag
    36901 atggattacc aaaacaagca actcattatc aaagcatgtt aagagcgtta gtcaagaagt
    36961 ataataagac ccatgaggac aagctaccaa agattacgcc acataccttt aggcatacac
    37021 tctgtacaaa tatggctaac aaaggaatga gtcctaatat attgcaatat attatggggc
    37081 ataaaaacat tactatgacg cttggctatt atgcacatgg ttcatttagt tcttcgagag
    37141 ctgaaatgga acggttataa tcctagtagt atgactagag tttactactt atttactact
    37201 tttgatggca ttcttatacg gttaaatgcc aacttatgca aagtatcttc caaaaagaaa
    37261 atgccgatac tccttgtaga tacaggatat atcgacattt accaacttat gaaaagataa
    37321 tcaaatttaa tataagtttt tcaaataaaa agataccaaa ttctttttcg agaatctata
    37381 taacattact taagcttggt tggggtataa acaattgagt agctactttt gtatggtgtt
    37441 caactttagt caaaactctt aagtaatgca aatgatttag attcattaat attcaatctc
    37501 ttcataagta gtgaaattcg agttatttct gcataattat actatgattt atagattaat
    37561 tctattagca tccagaataa tattgtttat atgagtaaaa tttaaagaat attgtgaaaa
    37621 ttataggatg ttaaaataaa tttaggtaaa aaagaagtgt ttgtatatta tagagtacct
    37681 tttctaaaat atgtgggatt gttttaagaa ttagaataaa aattattttt aaattagtat
    37741 ttttataatg tatagtattt ttaatgtata attaaattgt gcagaaaata gaatttaaag
    37801 tcctatagaa tttctgatta tggaggagaa tatgaaaaga aaagttcaag taaaaaatat
    37861 tactattgga gaaggtagac ctaaaatttg tgtaccaatt attgggaaaa ataaaaaaga
    37921 tattataaaa gaggctaaag agttaaaaga tgcatgtttg gatattatag agtggcgagt
    37981 tgattttttt gagaatgtag aaaatattaa agaagttaag gaagttctct atgaattaag
    38041 aagttatata catgatatcc ctttattatt cacatttaga agtgtagtag aagggggaga
    38101 aaaattaata tcaagagatt attatactac tttgaataaa gaaatttcta atacaggttt
    38161 agtagattta atagatgtag agttatttat gggagatgag gtcatagatg aagtagttaa
    38221 ttttgctcat aaaaaagaag tgaaagtaat tatatctaat catgatttta ataaaactcc
    38281 aaaaaaagaa gagattgtat ctcgtttatg tagaatgcag gaattgggcg cagatttacc
    38341 caaaatagct gttatgccgc aaaatgaaaa agatgtgtta gtgctacttg aagctacaaa
    38401 tgaaatgttt aaaatttatg cagatagacc aataataaca atgtcaatgt caggaatggg
    38461 tgttataagt agattgtgtg gtgaaatatt tggttctgca ttgacttttg gagctgcaaa
    38521 aagtgtttca gcaccagggc aaatatcatt taaagagtta aattcagtac ttaatctatt
    38581 acataagagt attaattaaa ttaattatat agaaatatta gacggtattt ttgaagatat
    38641 aaattaaata taaaaaactt ttcagatagt aaaatttaaa ttgggcaatt atatctgaaa
    38701 agcaactatt tagtgtgtat tttgaaagtg atatagaaaa tcttataaat caactatggc
    38761 atatttaaaa tatgccatta aaacctacta gacattagat tatagatggt atactagcat
    38821 ttctattatt tatagatagt aagttttcat aataactgtt ttatctaaag tagaagatat
    38881 atttgtatta tgtatatttg tcattatttt tttgtaatta tgtatattaa tggttatata
    38941 tgtaatataa tattatcact ctattttttg tatattgtac attacaacat ttatatctat
    39001 catcatcaat tacagtagaa tgtatgggat acttattttc acttaaccaa tatttttgca
    39061 tattctttgt ccaagacttt ggaaacttca atactttctt gtttattata acatcctcat
    39121 cttcaaaaat attaacttct ctttctattt ttatttttct gttgtatatc ttattgatag
    39181 attctttgtc gagttttatg tctctataca tatcagggca atagcaacaa acataatttc
    39241 ttttttttcg acgtttaaat ttcacaactt tctctatgct aatttctaat ttttttgtac
    39301 catcttttat aaatttaata tcttctatgt tctcgcttga aaaaatttct gtcaatctta
    39361 aagtatctac agtttctcta attatttgct ttttataaga agagaatcca tatccaaaag
    39421 aaaggtttaa tttattaggg atgtagccat ttttatattt aaacatctta attttttcca
    39481 attcagcatt atctttaaat ttcaactttt catacctaaa agttactttg ctaaaaagag
    39541 tatattctac atcaatatat tcttttgcaa tcttaaattt atcgctacct tcaatcacaa
    39601 tcatagccta tctccaatcg ttttatatta aaataaggcc atagaacatg gtctaatagt
    39661 actcattagc actataagac aatgttaaca caaaaagaca aaaaaaggtt atttatttca
    39721 aataaccttt ttttttatat aaaatataaa gaattatatt ttattctttt ttatgatgtc
    39781 tataatctgt gatatcagat ttagttctct tgaatttaag tcttttaact cttcatttat
    39841 atcattttct aaatatgttt ttccagtgga agtaatatct tttataagaa catctgcaga
    39901 aatatttaat atatttacaa attttatgaa tgttttaaga cttggattct ttttaccact
    39961 ttcgatttga gttatatacc aaggcgatac tccaaccata tttgcaaatt cttttgaagt
    40021 taaatttgct tttttccgtt cttctttaag tcttttacct atataattca ttattgttac
    40081 tatttccctc acttatattt ctttgtattt aatgatgcac tttattaact ctagcattgc
    40141 aatttgttct ttttcagtta atttattaat catttcataa cattctaaag gtacagagtt
    40201 atcaacgcct tctgttgtaa taatatttgc aaataacaat tcaagtggta tgtctaaagc
    40261 agtagcaatt ttcattataa tattgataga tgtatttgtc tcagctcttt caatctgacc
    40321 aatatatgtt ggatgtaaac ctgccttttc tgctagaaac tcttgactat atcccaattt
    40381 tgttctatag acttttattc tatctcctat tatttttcct atatttgcca attattatcc
    40441 ctccacttta gattatattc atagtttaag ttgttttata tagactattt atactttttt
    40501 agtctaaata tagactatat atgtttttat actgaaataa gtgctattta tttttgtata
    40561 gtctgtatct acaataaaca aatatggata aatcatattt ttaattagag aaatattttc
    40621 ataatttcat agccatacta caataataaa acgaattaat aatatgttaa ttatagcatt
    40681 ttttattgta attacatatt agatatgtag aatatatttt gaaaattaaa aaaattttct
    40741 attttatata ttgaacaatt tatgtgaata gaaaattttt caataagact tttgagttta
    40801 atcattatat tggtaa
//
LOCUS       DAYAOO010000032        38966 bp    DNA     linear   BCT 12-OCT-2024
DEFINITION  TPA_asm: Clostridioides difficile isolate ST8-SSI-h139-18
            SAMN40601845-rid21577343.denovo.032, whole genome shotgun sequence.
ACCESSION   DAYAOO010000032 DAYAOO010000000
VERSION     DAYAOO010000032.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN40601845
            Sequence Read Archive: SRR28438827
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 38966)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 38966)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-MAY-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-MAY-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002157583.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002157583.1
            Genome Coverage       :: 163x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/11/2024 16:19:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 4,038
            CDSs (total)                      :: 3,963
            Genes (coding)                    :: 3,930
            CDSs (with protein)               :: 3,930
            Genes (RNA)                       :: 75
            rRNAs                             :: 6, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 60
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 33
            CDSs (without protein)            :: 33
            Pseudo Genes (ambiguous residues) :: 0 of 33
            Pseudo Genes (frameshifted)       :: 7 of 33
            Pseudo Genes (incomplete)         :: 25 of 33
            Pseudo Genes (internal stop)      :: 11 of 33
            Pseudo Genes (multiple problems)  :: 8 of 33
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..38966
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN40601845-rid21577343.denovo.032"
                     /isolate="ST8-SSI-h139-18"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Denmark"
                     /collection_date="2018"
                     /collected_by="Statens Serum Institute"
     gene            207..866
                     /locus_tag="ACGI5H_001840"
     CDS             207..866
                     /locus_tag="ACGI5H_001840"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439467.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine kinase"
                     /protein_id="HFG9697543.1"
                     /translation="MLDAFITIVSSIIEIWSCKKVFDYTSQSKTDLKKLNMYFLFSVF
                     LIISSLYINIGANSRILICIFVMFVFYKSNYKVNIYKCLVISFFYWLILIGINGLSML
                     LVATVSNLDNMNVLLSGSLYRYEAIFLGKIMLGILLYVYKASFKNFKISKKEIYICIP
                     MIANLLSFFVLYDYIINLVKISPERRTAFLVIVLLLILSNISIFVLIHIILKIKIRKI
                     R"
     gene            1160..1501
                     /locus_tag="ACGI5H_001841"
     CDS             1160..1501
                     /locus_tag="ACGI5H_001841"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889774.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LytTR family DNA-binding domain-containing
                     protein"
                     /protein_id="HFG9697544.1"
                     /translation="MKEENFINVEYEDKRFSINSKEVLYIEKQEYEVKIYTESGNYEV
                     GENAPCIRKLLKEENFFKCSNSYIVNLDKCEFYLSNNCIFVNNNFIRILGSERKKKLK
                     KKLEKLYDYED"
     gene            1652..2065
                     /locus_tag="ACGI5H_001842"
     CDS             1652..2065
                     /locus_tag="ACGI5H_001842"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897017.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1653 domain-containing protein"
                     /protein_id="HFG9697545.1"
                     /translation="MLELKNNLGISERKLKYPCIYKHFKGKYYATMGLSKAIDDIENI
                     CEIYGKENLIQNRNKYKLVIRHTEREEDIYVYRDLDGNFYHKKEEDTNDLVLYKTLYD
                     DTGIFARPLDMFLEKVDTDKYVNSIQEYRFEEVYK"
     gene            2267..2908
                     /locus_tag="ACGI5H_001843"
     CDS             2267..2908
                     /locus_tag="ACGI5H_001843"
                     /EC_number="3.1.3.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902783.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine phosphatase family protein"
                     /protein_id="HFG9697546.1"
                     /translation="MGNTFYIVRHGQTDWNILGKTQGHGNSDLTPQGIEQAKELSEDI
                     GKYSIDYIFSSDLGRAMQTAQILGDKLNIEVQKTEALREMGFGVWEGLLIKEIQKDYS
                     DIYATWRNEPHLVNIPEGETLKIIKERVDAFIKELNEKYDNKNIILVTHSITLRVMLL
                     SFLESGMENIYRIKQDNTALNIVEFKDYGPVIVKMNDTSHIKNHVKINNSALE"
     gene            2932..4185
                     /locus_tag="ACGI5H_001844"
     CDS             2932..4185
                     /locus_tag="ACGI5H_001844"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439456.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="HFG9697547.1"
                     /translation="MSKVIVVGGGASGMMAALSASKNNNEVILVERNGELGRKLRATG
                     GGRCNFTNNREIEDFFDKVVSNKKFLYSSFYTFTNKDLISYFESRNLEYKIEEENDHK
                     VYTKNDKSIEVIEVLNKDLLNHNVKIMYNKKVIDIITEEIALKDDSNKDKSKYLIKGI
                     ILDNGDKILGDKVIISTGGVSYSKTGSDGSMYKILKKHGHTLNKLYPALVPLTIEEKW
                     IKDLQGISMKNVEISCKIKKRKISKSGDMLFAHFGITGPCVLIMSSYINKIIEKEKVE
                     LNIDFLPNLSTDEISSIIRAFPNKNVLNNLKQILPQNFLKEIFSLLSLVDKKASDLSK
                     ADEIRIIEYIKNMKLTCNGTTGINTGMVTSGGISVKEINSSTMESKLVKNLFFTGEVI
                     DIDAETGGYNLQIAFSTGYLAGISV"
     gene            4231..4881
                     /gene="cmk"
                     /locus_tag="ACGI5H_001845"
     CDS             4231..4881
                     /gene="cmk"
                     /locus_tag="ACGI5H_001845"
                     /EC_number="2.7.4.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728624.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004127 - (d)CMP kinase activity [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0015949 - nucleobase-containing small
                     molecule interconversion [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="(d)CMP kinase"
                     /protein_id="HFG9697548.1"
                     /translation="MGNLVIAVDGPAGAGKSTIAKIVAKKLNINYIDTGAMYRAVTYK
                     CLKSGIDVNNEKEVIQIAENSDIDFKDNNIYLDKEVINEEIRTIEVSNNVSNVAKIKE
                     VRQLMVEVQRKIGMKNSVILDGRDIGSYVFPDADYKFFLVATPEERGNRRYKELCNKG
                     YNTTLEEVIEDIIRRDEIDSNREFAPLVKANDALEIDTTGKTIEEVVEEVVSKINL"
     gene            4932..5528
                     /locus_tag="ACGI5H_001846"
     CDS             4932..5528
                     /locus_tag="ACGI5H_001846"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423868.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lysophospholipid acyltransferase family protein"
                     /protein_id="HFG9697549.1"
                     /translation="MNFYRFVINIFKGFSKIFFKYEVIGAENIPDRGNIVIASNHKSN
                     LDPIFLAAAIENREIAAIAKKELFKVKPLGFILKKLHVMPINREKPDVSTIKTILRSV
                     RDGYVLGIFPEGTRIKGDSFGKAKAGLSVFTIKSKSKVVPVSIISKYKLFSKVIVYIG
                     EPISFEEHFKEKLSNDDHERISQEILEVIKQNYFKYSK"
     gene            5541..6380
                     /locus_tag="ACGI5H_001847"
     CDS             5541..6380
                     /locus_tag="ACGI5H_001847"
                     /EC_number="1.17.7.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893304.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-hydroxy-3-methylbut-2-enyl diphosphate
                     reductase"
                     /protein_id="HFG9697550.1"
                     /translation="MNIKIAKNAGFCFGVKRAMKMAWDEVEKNDSGIYALGPLIHNKQ
                     AVAKYEEKGLKTVNEIDTIPNHENMIIRSHGVPENIYKEAKDKKLKIVDTTCPFVKKI
                     HTVVSEYHNKGYEIIVIGDMKHPEVIGINGWCENSAIIIKTLEQMENMEFDNSKRYCL
                     VAQTTINPELYISIVNKLSDKLEEIVFNDTICSATKTRQESAKELAKEVDCMIVIGGK
                     HSSNTQKLVKVCEDLVPTFAIETKDELDVNTLKKYKNLGITAGASTPNWIIEEVVTFL
                     ENL"
     gene            6625..7779
                     /locus_tag="ACGI5H_001848"
     CDS             6625..7779
                     /locus_tag="ACGI5H_001848"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897020.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative manganese transporter"
                     /protein_id="HFG9697551.1"
                     /translation="MEMLISASEEAFLHVGSMIGFFILLFGYINYKTSGNFTNIISKN
                     RKFQPLIGALIGAIPGCGGSLAIMPLYINGKLSFGAIIASLIASMGDAAFVLISSNIK
                     MYFFVTIVSTITGIITGQLVDYFKLEEKLGLKNRRKSDKYDISKNNPKENKEQHNHDE
                     IILDTLAKSHGNTNRLAFIITHGKGYKIYIGIIVIGFIFMSLAHSGLNLPIIEKLHSL
                     EEVIAVIGILFSIIYMWCFKKVFKNSNQKEEENKKISLREMLIHSVGEISFVITWIFI
                     AYLIYDLIILILGGDEYLVKLVLSTGVISVFIGAGLGLIPGCGIQIVLMSFYLKGTIP
                     LGAVIANSISQDGDALFPLLAMDKKSSLWAMIITTIPAILVGMIVYAFLG"
     gene            8085..9782
                     /gene="ade"
                     /locus_tag="ACGI5H_001849"
     CDS             8085..9782
                     /gene="ade"
                     /locus_tag="ACGI5H_001849"
                     /EC_number="3.5.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728625.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000034 - adenine deaminase activity
                     [Evidence IEA];
                     GO_process: GO:0006146 - adenine catabolic process
                     [Evidence IEA];
                     GO_process: GO:0006168 - adenine salvage [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="adenine deaminase"
                     /protein_id="HFG9697552.1"
                     /translation="MGNLKRQCDVSSGREKADIVLKNGTIINVFTEELITGDVAIVGD
                     TIVGIGDYKGNVEIDCSNKYISPGFIDAHMHIESTMVMPIELSKKLLKSGTTTIIADP
                     HELVNVKGVSAIDFLLESTKDIPLNVYIMVPSSVPATSFETNGVGKFSAKDMESYVNN
                     PRILGLGEVMCFNDVINSENEILDKLELFKNKVVDGHAPNINGKSLQTYVCAGIENDH
                     ECITFDEVYEKLRAGLKILIREGSAAKNLKSIVSGMLKHNLPIEEFMFCTDDKHLDDI
                     EKQGHIRWNIKCAIDLGMEPVRAIKVATYNSAKAYGLRKIGAIGAGYKADIVVLNDLD
                     KMEVDSVYKDGNLVNEEMFSNYNYEIKDKELLNTVKFKYINKEKIQLKVSEKNYVMEI
                     VPYQILTNKVYESLPCADGYFVPNKEYSKLCVVERHRMTGNVAIAPLKGFGIKNGAIA
                     TTVAHDSHNIIVAGDNDDDILVAINYLKEIQGGYVIVSNGKVLAHLSLQVAGLISTFT
                     AEEVQEITDNMLEIARKMEVPEYVDPFITLSFMALPVVPQIRLTDLGLFDVEEFKFI"
     gene            10134..10598
                     /gene="bcp"
                     /locus_tag="ACGI5H_001850"
     CDS             10134..10598
                     /gene="bcp"
                     /locus_tag="ACGI5H_001850"
                     /EC_number="1.11.1.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439443.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016209 - antioxidant activity [Evidence
                     IEA];
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin-dependent thiol peroxidase"
                     /protein_id="HFG9697553.1"
                     /translation="MLSIGTKAPEFTLEDKDGNKVSMSDFKGKKVVVYFYPKDNTPGC
                     TRQACAFRNAYDGFKKEDIQVIGISKDSIKSHQKFAEKHELPFILLSDPDLVAIKAFD
                     VWKEKKMYGKTALGVVRATYIIDENGIIEKVFEKAKPDTNAQEILEYLEKQE"
     gene            10608..11351
                     /gene="yaaA"
                     /locus_tag="ACGI5H_001851"
     CDS             10608..11351
                     /gene="yaaA"
                     /locus_tag="ACGI5H_001851"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428614.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peroxide stress protein YaaA"
                     /protein_id="HFG9697554.1"
                     /translation="MIIMLSPAKNMKNIEVFDRDLSLPCFIDNTKEIVENIKTFGIED
                     FKNKMKINEKLAVLNKNRFESIKFDRLGNPAILTYDGIQYKNIEAENFTRKDEEFANS
                     CIRIISGLYGVVKPYDSIYEYRLEMQTKLQVGEFKNLYEYWGNRIYKELIKEKTAIVN
                     LSSNEYSKSIEKFIKDSDTYITCTFKVNKNGILKVESTQAKKARGMMTKYIVKNRIRD
                     IEELKKFDLEGYKYKENLSNNSEYIFVKE"
     gene            11449..14136
                     /locus_tag="ACGI5H_001852"
     CDS             11449..14136
                     /locus_tag="ACGI5H_001852"
                     /EC_number="7.2.2.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728628.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0005388 - P-type calcium transporter
                     activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006816 - calcium ion transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="calcium-translocating P-type ATPase, PMCA-type"
                     /protein_id="HFG9697555.1"
                     /translation="MKKRKEWSSKMENHKQMPWHSRATHEILESLDSSEEGLTDTEAE
                     KRLKENGLNELRKKPPRTTLQMLWSQITDAMVMILIGAAILSLIFGEFTEAFVILIIV
                     TVNAVIGIVQEKKAESSLEALKNMNSPTARVMRDGEENVIPASNLVVGDIVFLEDGAM
                     VPADLRLIETSSLKIQEASLTGESVPSEKDADTILPKECVLGDRSNMAYTSSIVTYGR
                     GVGVVVATGMDTEVGNIAHLLDSQDDFDTPIKRKLNTVGKTLSVIGIIVCVVIFAIGA
                     FYQRPLLPMFMIAISLAISIIPEGLPATATIVMALGVQRMAKRNALIRKLPAVETLGG
                     ATVICCDKTGTLTLNKMTVTHIAVNGDFESGKVTSIDTASEKHPLVYKEIVYAGALCN
                     DACINPDKTDEILGDPTEGALIFMAKKFGIDQEALEEEYPRVFEQPFDSDRKCMTTVH
                     NIDEKIIAYTKGAVDEILDLCTKILTSKGERNITEVDKKNIHELCLNMSKDALRVLGF
                     AKREISSIPKEDSENIEYDLTFIGMVGMIDPPRTEVIDAVSTCKEAGIRTIMITGDHK
                     VTATTIAHELGIWSEENTVISGDELDNLSDDELDEAVKNTTVFARVSPFDKLRIIQSL
                     KRIGEVPAMTGDGVNDSPALKSADIGIAMGISGTDVAKDSSDMILMDDSFTTIAYAIK
                     EGRRVYRNIQKVIQFLLVGNIAEILTLFVAILLNWDTPLLAVHILWVNLATATLPALA
                     LGVDPPSRNIMKHQPVKSTTLFEKNLIQRVVTQGIFVAIMTILAYKIGLNIENHSVGQ
                     TMAFCVLAFSQMLRAFSQRSNTDSMFNRNNGKNPFLLISFLTSAFLIAVILFVPVFRN
                     AFNLTVLNNLEWLVTIVLAIMSVIQVEVGKIIKRKKLKK"
     regulatory      14190..14292
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00162"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="SAM riboswitch class I; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="S-adenosylmethionine"
                     /db_xref="RFAM:RF00162"
     gene            14402..15667
                     /locus_tag="ACGI5H_001853"
     CDS             14402..15667
                     /locus_tag="ACGI5H_001853"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728629.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016765 - transferase activity,
                     transferring alkyl or aryl (other than methyl) groups
                     [Evidence IEA];
                     GO_function: GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA];
                     GO_process: GO:0019346 - transsulfuration [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="O-acetylhomoserine
                     aminocarboxypropyltransferase/cysteine synthase family
                     protein"
                     /protein_id="HFG9697556.1"
                     /translation="MYNKETICVQGNYKPGNGEPRVLPLYQSTTFKYSSIDQLAELFD
                     LKVDGHIYSRISNPTIQAFEEKISLLEGGVSSVAVSSGQSANMLAVLNICKSGDSILC
                     SSKVYGGTFNLLGPSLKKFGIDLISFDLDSSEDEIVELAKENTKVVFAETLANPTLEV
                     IDFEKIANVAKRINVPFIVDNSLASPVLCNPLKYGANIVTHSTTKYLDGHASSVGGII
                     VDGGNFNWDNGKFPELVEPDPTYHGISYTQKFGNAAYATKARVQLLRDYGNCLSPFNA
                     YLTNLNVETLHLRMERHSENALKIARFLEKHENVDWINYPGLEDNKYYENAKKYLSRG
                     CSGVLSFGVRGGLENAKKFVEKLQIASLVTHVSDVRTCVIHPASTTHRQLTEEQLIAS
                     GVLPSLIRLSVGIENVEDLIADLNQALNF"
     gene            15697..16587
                     /locus_tag="ACGI5H_001854"
     CDS             15697..16587
                     /locus_tag="ACGI5H_001854"
                     /EC_number="2.3.1.46"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423895.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004414 - homoserine O-acetyltransferase
                     activity [Evidence IEA];
                     GO_function: GO:0008899 - homoserine O-succinyltransferase
                     activity [Evidence IEA];
                     GO_process: GO:0019281 - L-methionine biosynthetic process
                     from homoserine via O-succinyl-L-homoserine and
                     cystathionine [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="homoserine O-succinyltransferase"
                     /protein_id="HFG9697557.1"
                     /translation="MALILPKGLPVINKLLDEGIDVIYKEDFKKELKYEENIDTKIAI
                     LNLMPIKIDTELDLLRRIDKTGFNVSVEFIKISTRESKRSCNEYVKEFYKTFDEAKGE
                     YFDGFIITGAPVEQMEFEEVDYWNELEEIMDYSKRKTKSTLYICWAAQASLYKYYNVK
                     KLPLSQKCFGVFKHKVDKDSKIVDGFENEFFAPHSRHTTVNIEALKENKELSIVSHSK
                     EAGPYIITNSRDVFVMGHSEYDKYTLDKEYKRDINKGDKISIPQNYYINDDPSEEPTV
                     KWKKHSELLFRNWIKNYLIQ"
     gene            17078..17521
                     /locus_tag="ACGI5H_001855"
     CDS             17078..17521
                     /locus_tag="ACGI5H_001855"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423898.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HFG9697558.1"
                     /translation="MDEMSFKKELLELTRDINMKFTTLLSDFYQPLGITAVQALILSE
                     LCEHGEKKISDLGKNLNMTNSNVSVICQRLEKNGFLNRIRDIEDQRIVKVKVTNKSLD
                     IQEHISSSIFDSYFENMTSEKLQDMEDIIEGLEKLNKLLTYIDCK"
     gene            17552..19369
                     /gene="ftsH"
                     /locus_tag="ACGI5H_001856"
     CDS             17552..19369
                     /gene="ftsH"
                     /locus_tag="ACGI5H_001856"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423899.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0004222 - metalloendopeptidase activity
                     [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA];
                     GO_process: GO:0051301 - cell division [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent zinc metalloprotease FtsH"
                     /protein_id="HFG9697559.1"
                     /translation="MDEHKPQKRSALYYYTVIIIVVMFLNALIFPSLMDKKMVEIDYG
                     KFLTMLDTGKVKSVEIENNRIAINPSSSKDKNIYITGRMDDPELVDRLKNAKVEFTKV
                     IPKENSPLLSILLTWIIPIGILMLFGNLMMKSMQKRMGGNAMQFGKSNAKMYVSAQSG
                     KRFNDVAGQDEAKEALTEIVDFLHNPEKYKKIGAQMPKGALLVGPPGTGKTLLAKAVA
                     GEANVPFFSISGSEFVEMFVGMGASRIRDLFKQAKEKAPCIVFIDEIDTIGKKRDNGS
                     GLGGNDEREQTLNQLLSEMDGFDGGIGVVILAATNRPDSLDKALLRPGRFDRRIPVEL
                     PDLGGREAILKVHAQNVNVSSDIDYNAIARSTSGASGAELANIVNEAALLAVKSGRDI
                     VEQQDFDESVETVIAGYQRKGAVISDKEKKIIAYHEIGHALVAAMQKHSAPVHKITII
                     PRTSGALGYTMQVAEDESVLMSKEEAIDKITTFTGGRAAEEVIFNTCTSGASNDIEQA
                     TKIARAMVTRLGMSEEFDMVALETVSNQYLGGDTSLACSSDTAAKIDEEVFKIVKACH
                     KNAIEILENNIDKLHELANYLLEKETITGDEFMEILNLN"
     gene            19547..22249
                     /locus_tag="ACGI5H_001857"
     CDS             19547..22249
                     /locus_tag="ACGI5H_001857"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897026.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HFG9697560.1"
                     /translation="MDRPNPDILLEKIKNEEEKLSRGQLKIFFGYAAGVGKTYSMLES
                     AQNLKKVGVDVVVGYIEPHTRPETLALLDGLEILPVKEIEYKSIKLKEFDLDAALARK
                     PEVILVDEFAHSNVAGLRHTKRWQDIEELLLAGINVYTTVNVQHLESLNDIVEIITNV
                     SVKETIPDKFLDTNTQLELIDVEPDVLLERFNEGKIYKKEQATRAKNNFFIKDNLVAL
                     REIALRKTAERVNKEVQMTRLSKGDVTVIPTSDTLLACISPSPSSAKVIRTASRISDS
                     TFAKWIALYVETPNTARLPFDEQKQLQNNLKLAKKLGGEIIVLHGENIIEQILRIAKL
                     RNVTKIVIGRNHSSNKRFSKRFKKDIVDKLIDEVDYIDIHIIPYKFASDVKYKPKKDK
                     SSIKSKFKISKVDFIKLIFITLMISILAYAVQSMGFIRENILLIYMLGVVLVSMWTKG
                     YSTGIISSVFNIVLLNYFFTAPLYTLSIADSNYIVTLVVFSIVGIITSTLTSKIQHEA
                     ETAAKREENTKMIYQIIKGFLRLSNKDDIVNKGIELLSLSLSRDVICYLNVDKHNKSK
                     LYKKNTNNKDKNDLDSEDEKAVASWVLSNSTVAGNDTDTLPGSKGYYIPIVGMNLTLG
                     VVGISCIDSKLDTEDISLIETIIAQMAIALDREILSEAKENTNLEIERERLRSNLLRA
                     VSHDLRTPLAGISGAVSTIIKNKGTIGQDIIDELLSGVYEDTQWLIRLVENLLSMTKI
                     DEGKLEVKKHSELVEEIISEALQKIKKRIENALIDINIPEQILFVPMDAKLIEQVLIN
                     LIDNSLKYSKEDCKIEINVYEKDDYVWFEVSDNGPGISKELKKHIFDRFFTGEEGAKD
                     SRKGVGLGLSICKSIIQAHKGEIMVENNKDKGSTFKFSLPKENE"
     gene            22283..22981
                     /locus_tag="ACGI5H_001858"
     CDS             22283..22981
                     /locus_tag="ACGI5H_001858"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439430.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HFG9697561.1"
                     /translation="MSKKLILLVEDDKTIRKFISTALLTQDYDVKEAITGKEGISIAV
                     SYSPDVVLLDLGLEDMDGIEVIKAIRQFSNIPIIVVSAREQDRDKVEVFDAGADDYLT
                     KPFSIVELLARVRVAFRHSQVEAQQKDDVKSTFEVDKLLIDFDKRKVIVDDVEVHLTP
                     IEYNILSLLAKYHGKVLTHNFIIKEIWGSVIGNETKSLRVFMATLRRKIEKQPANPRY
                     IITEVGVGYRLNDE"
     gene            23338..24294
                     /locus_tag="ACGI5H_001859"
     CDS             23338..24294
                     /locus_tag="ACGI5H_001859"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728630.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CorA family divalent cation transporter"
                     /protein_id="HFG9697562.1"
                     /translation="MYILNLNTRETIEDFRDKFYVAENSYLILSAPKNLKLLKETLDI
                     DEITFNDCLKFDEITKLDLFDNYDFLSLNTFELRDGEAVIEEVNMYLSDNFILVVVNE
                     EHFLFEFVKNIILKNSQLEKNPVINLFKINYLILREVIKNGFESLEKVEELILQIEDE
                     MMDNINKNHVSRISDVRGLTRIIVKNTRPLLYIGDRIVKENIRYLKYSNVKKYNLENF
                     QGIDFGIDKLYNFALSTRELADKLLDIYSSRVGEKTNNLITKLTLLTAISAPLTIITG
                     IYGMNFRYMPELNWIYGYPATLFFMLCIIFVGIIIFKIKKLL"
     gene            24471..24626
                     /locus_tag="ACGI5H_001860"
     CDS             24471..24626
                     /locus_tag="ACGI5H_001860"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428626.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9697563.1"
                     /translation="MKGILKELTAKLYSFFYFMFWGFYFSAGYFFYKNICTSFLVRPY
                     FSDFEHK"
     gene            24756..25769
                     /gene="aroF"
                     /locus_tag="ACGI5H_001861"
     CDS             24756..25769
                     /gene="aroF"
                     /locus_tag="ACGI5H_001861"
                     /EC_number="2.5.1.54"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423903.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003849 - 3-deoxy-7-phosphoheptulonate
                     synthase activity [Evidence IEA];
                     GO_process: GO:0009423 - chorismate biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="3-deoxy-7-phosphoheptulonate synthase"
                     /protein_id="HFG9697564.1"
                     /translation="MIVVLKMGADKNEVKKLIEAIGREGVEVNPIDGTELTVLGLVGD
                     TSKIDAKRIEANKVVEKVMHVVEPFKKANRKFHPEPSIINVNGMEIGSKKIAMIAGPC
                     SVETEDQIVSIAKDVKKSGAGFLRGGAFKPRTSPYAFQGLKYDGLDLLKKAKEKTGLP
                     IVTEIMSTQDIDIFEENVDVIQVGARNMQNFDLLKELGKTNKTILLKRGLSATIEEWL
                     MSAEYIMAGGNENVVLCERGIRTFETYTRNTLDLSAILAVKKLSHLPVIVDPSHAAGK
                     SWMVDSLSKAAIAVGADGLIIEVHNDPAHALCDGKQSIKPNEYDELISELKTIASAVG
                     REI"
     gene            25791..26855
                     /gene="aroB"
                     /locus_tag="ACGI5H_001862"
     CDS             25791..26855
                     /gene="aroB"
                     /locus_tag="ACGI5H_001862"
                     /EC_number="4.2.3.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423904.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0003856 - 3-dehydroquinate synthase
                     activity [Evidence IEA];
                     GO_process: GO:0009073 - aromatic amino acid family
                     biosynthetic process [Evidence IEA];
                     GO_process: GO:0009423 - chorismate biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="3-dehydroquinate synthase"
                     /protein_id="HFG9697565.1"
                     /translation="MEEKLLVNLKENSYNIFIKKNILKNIGEEIKKIYFGNKIFIVTD
                     ENIAKLYLDKVKNNLSESGFEIKSLILKSGEETKSFNTLPKIYDSLLDFKLTRKDLII
                     TLGGGVIGDLGGFAAATFLRGISFIQIPTSLLAQVDSSVGGKVGVDLERGKNLVGSFY
                     QPKAVFIDPNVLLSLPEKFYRDGMAEVIKYGCIKDKTFFNKLLSLKNREEVMQHIEYI
                     IHKCCFIKKTVVEADEKDFGDRMLLNFGHTLGHAIEKYYNFTGYTHGEAVAIGMYKIT
                     LESEKIGITKKGTSELIKSILMNYNLPYEIELRDNKSIVDAISLDKKNLGDTLKIILL
                     KDIGESIIYNTTSKFFQEVR"
     gene            26855..28168
                     /gene="aroA"
                     /locus_tag="ACGI5H_001863"
     CDS             26855..28168
                     /gene="aroA"
                     /locus_tag="ACGI5H_001863"
                     /EC_number="2.5.1.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902796.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003866 - 3-phosphoshikimate
                     1-carboxyvinyltransferase activity [Evidence IEA];
                     GO_process: GO:0009073 - aromatic amino acid family
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="3-phosphoshikimate 1-carboxyvinyltransferase"
                     /protein_id="HFG9697566.1"
                     /translation="MGSLKIYPSKLSGDVKIPPSKSMAHRAVICSSLSNGKSRISNID
                     FSDDIIATIRAMTSLGAIIEKKEDILEISGIFSKEGILNRENQLNQPKLTIDCNESGS
                     TLRFLVPISLTFDGVKRFIGRGNLGKRPLDTYYEIFDRQNIKYSYKENQLDLIISGKL
                     KPDEFRVKGNISSQFITGLLFILPTLESDSKIIITTELESKGYLDLTLSTIKDFGVEI
                     INNNYKEFIIKGNQTYKARDYKVEGDYSQGAFYLSADAIGEDISILDLKEDSLQGDSE
                     VVEILSRMGMEILREGNKIKGITNGLNGTLIDASQCPDIIPVLSVVASLSIGRTTIIN
                     AGRLRIKECDRLHAINVELSKLGANIEEKEDSLIIEGVSKLNGGVEVWSHKDHRIAMT
                     LAIASCRCDKPIILKDFECVSKSYPHFFKDFKMLGGRIDEWNMGK"
     gene            28146..29225
                     /gene="aroC"
                     /locus_tag="ACGI5H_001864"
     CDS             28146..29225
                     /gene="aroC"
                     /locus_tag="ACGI5H_001864"
                     /EC_number="4.2.3.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902798.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004107 - chorismate synthase activity
                     [Evidence IEA];
                     GO_process: GO:0009073 - aromatic amino acid family
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="chorismate synthase"
                     /protein_id="HFG9697567.1"
                     /translation="MSGIWGNNLKVSIFGESHGNAIGINIDGLPSGIELDLDNIDKEM
                     KRRAPGKNSISTSRNESDIPEILSGYFNGRTTGTPLCAIIRNSDTRSKDYGELKNLMR
                     PGHADFTGNVRYSGFNDYRGGGHFSGRITAPLVFCGAICKQILSQKGIEIGAHIKKIK
                     NIEDMSFDYVNISKQQLSNLQTLELPLLDLSKEEAMKNTIIDAKNQGDSVGGIIECAV
                     VGINVGLGNPFFDSVESTLSHLLFSVPAVKGVEFGLGFELADMYGSQSNDEMYYEGNQ
                     VKSKTNNNGGIIGGITTGMPIIFKVAIKPTPSISRQQNTVNIKDKKDDILYIKGRHDP
                     CIVQRAIPVIEAVTAIGIFDLMKGR"
     gene            29228..30424
                     /gene="pheA"
                     /locus_tag="ACGI5H_001865"
     CDS             29228..30424
                     /gene="pheA"
                     /locus_tag="ACGI5H_001865"
                     /EC_number="4.2.1.51"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428637.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004664 - prephenate dehydratase activity
                     [Evidence IEA];
                     GO_process: GO:0009094 - L-phenylalanine biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="prephenate dehydratase"
                     /protein_id="HFG9697568.1"
                     /translation="MEDLTRYRNEIDNIDKELIQLFEKRMNTVLEIARHKMKNNTTIL
                     QKDREEKVLSRAVDNLDNKAYSQETVQFFNSIMEISRGLQKRLIDNDGEQKIEFSLDS
                     SNKKFDLSNVNRYKSLKDELNKKNILVGFPGKSGSFTEEALNKFFNKKISKKQFKEFE
                     DVFIALKNKEINYGIIPIENSSTGAISETYDLLRKYGFYIVGEECIKIDQNLIGIKDT
                     KLEDIKEIYSHPQGIGQCSKFLKQNSTWKLIPFNNTATSAELVRKLQDKTKAAIASKK
                     AASIYGLEIISPCINDIANNYTRFVVISNQIHIEEESNKMSVVFSVEHEAGKLYKVLG
                     YFAKNNINMTKIESRPMKNASWRYFFYIDFECSIYNAKVYDLLELIEHNTAYFKFMGV
                     YKNKTE"
     gene            30471..31280
                     /gene="aroE"
                     /locus_tag="ACGI5H_001866"
     CDS             30471..31280
                     /gene="aroE"
                     /locus_tag="ACGI5H_001866"
                     /EC_number="1.1.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902802.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004764 - shikimate 3-dehydrogenase
                     (NADP+) activity [Evidence IEA];
                     GO_function: GO:0050661 - NADP binding [Evidence IEA];
                     GO_process: GO:0019632 - shikimate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="shikimate dehydrogenase"
                     /protein_id="HFG9697569.1"
                     /translation="MNFFGLVGEKLSHSVSPQIHKRVFEILNIESAYKNFEISKEDIS
                     KLDGAIKLLGIQGVNVTVPYKERIMKYLDFISPEAKRIGAVNTILLRENMLYGYNTDY
                     FGLDSMFKMANIDVQGKVAVILGTGGASKAALTYFIDSGIEKLYVSTRKKDDKKLLNS
                     KAILIDYEELKHIKGDIILNATPVGMYPNVGISPVSKSIIQNFDILIDLIYNPGETEF
                     LRIGNSMGKKTCDGLYMLVGQAIKSQEIWQDTKIDNSILDVIYNELKLEFL"
     gene            31292..31825
                     /locus_tag="ACGI5H_001867"
     CDS             31292..31825
                     /locus_tag="ACGI5H_001867"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439413.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="shikimate kinase"
                     /protein_id="HFG9697570.1"
                     /translation="MINKTKEKLILIGMPGSGKTTIGKLLAKEYNCSFCDMDDYIIQI
                     SQKSIAELFSEGEDIFRNYETQACRELSISDKTVISTGGGVIKKDVNMEILKETGIII
                     FIDRPIQKILEDININSRPLLKNGKDRLYNLYNERINLYKKFSDIEILNDKSLNNAVY
                     NITNAVSENFKFDFKEK"
     gene            31846..32685
                     /locus_tag="ACGI5H_001868"
     CDS             31846..32685
                     /locus_tag="ACGI5H_001868"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897031.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prephenate dehydrogenase"
                     /protein_id="HFG9697571.1"
                     /translation="MNIVIVGLGVIGGSFAKALKKAGYENVFGVDVDLETLKKAEKAK
                     IIKKGCTTGKELFKKADLIILSIYPRLVVDFLNNNKNFFKKGTIITDTTGIKETLIND
                     VLQIIPDDIDFIFGHPMAGREKKGIDFASEQVFNGANYIITPTGRNNIKNLELVENLI
                     LEIGFKRVKKLTSQKHDEIIAFTSQLPHVMAVALINSDEEGRDTGKFIGDSYRDLTRI
                     ANMNEDLWSELFLGNRDNLLKVIENFESEVNLVKEAIFNNDKNKLIEYFKKSSIRREA
                     LEK"
     gene            32953..34434
                     /locus_tag="ACGI5H_001869"
     CDS             32953..34434
                     /locus_tag="ACGI5H_001869"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893314.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative bifunctional diguanylate
                     cyclase/phosphodiesterase"
                     /protein_id="HFG9697572.1"
                     /translation="MKKNRLIAKNISIAFIVLFFFSVFTFFYVGNINRVLEYETNDII
                     TVTIAGWIILSFLFLGIIIYILYSKANSQKTIEKVAYTDFVTGYSNWRKFELDVTNLL
                     KKTSQNNKYAMVIFDIDKFKAINDIYGHKKGNLILKDIADTLNELTDINETFARVSAD
                     NFNILLTYNKKEDIINIIKKIMANNELVNLSFGIYEIKDKDLSVSVYSDRASLAKSSI
                     KNNSDVNFAFFNDKLREKLLFEDKIEKEMEYALESGQFVMYLQPKYNIKLDKFCGSEA
                     LVRWQYTEKEVIYPGDFIPIFEKNGFIRKIDMYILEQACKEIRSLFDKGISPLPISVN
                     FSRVDFFKKDFIENIVNICDRYKIPYSLIEIEITESSMFGDTDTLFNVSRNLQDIGFI
                     VAMDDFGSGYSSVNMLKNIPLNVIKLDRGFFVDDKDVDKSQIVIKSIVSLIKQLGIRV
                     VAEGIETRSQIEMLKKANCDIVQGYYFSKPLPIKEFEKLVYKI"
     gene            34467..37901
                     /locus_tag="ACGI5H_001870"
     CDS             34467..37901
                     /locus_tag="ACGI5H_001870"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423923.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005515 - protein binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PAS domain-containing protein"
                     /protein_id="HFG9697573.1"
                     /translation="MIRAKSLKNVLSIVLIFLFTIISFSDFAFKTNVQEEENSKINLR
                     EISLQSSNAIKIKLDSSLSFIKSVANMVSYFNTIDNSKIVPLLANISKESDFQRISIV
                     SPDGISHTSDGKIINVSKYQYFKKAIKGESNISEVVKSPIDGKDTFVIATPVFNKNNK
                     IIGVLYGSYYNDKLAEFIDITSFNSEGYIDIFESSGQFVLKSSHTNKLIKSSSNIYDI
                     FKKASFDDGYSYKKIYEDTKNNKSGFTSYEYKGENRYATYTPIGVNDWYVISVIPQYT
                     VRRNIDKINQLAFSLIFKVFLLFIMLIIYIIYKNNKSQKDILKANKEISSITNSIPGG
                     VQKCTLGETCNINFLSDGFIELFGYTREEIKTLFNNDFYSLIHKDDVERIKKEIFKQL
                     YKNKTVELEYRIITKNGNTVWVLDKGELITEPDGKEYFCCVTVDITRTKQLEQEMEQK
                     NLELEMISENVLGGIIITEFNDDFTIKYANSGYLSMIGYTREQLENELKYKACNLVFY
                     EDKKKALESIQHQLNTKGIAVYQHRIRRRNGNIIWVSIKGRLIVDDGIEKGIWILNDI
                     TDLKNAEQKLKINEERFRIALKQTSNTIFEYDIKTKSLLNTSKELDKYNIYKITKNVP
                     YSLVESGVIHKDFSDDFINMYENVINGAKKASCVVKMKLPDENYIWNKVTLTTIFDED
                     GNPVRAIGIQEDISKQKEAEIRYNQEGKYHSAILSEAMITYEINVSKDTFIKGNESWQ
                     KPFGIKPDNNYSQMVKTIANSIVHKDNKETFLNTFLCENLLDAYKNNVTEIKLEYRRM
                     NQENKMIWVICTMHLIKDSITNDIKALAYVKDIDKQKNEEIRLKLKAERDTLTGLYNK
                     GTTEKLINDFLNSEEASLGMHAFLIVDIDNFKSVNDNLGHVFGDKVLFEVSKNLKPIF
                     RKDDIVGRIGGDEFIVFLKNIQSFENIKKKAEKICDIFRNSYTENKKTYKISGTVGIS
                     FVPEHGTVFEELYKKADIALYYAKSKGKDKYALYNDCIYQNELENNISDNNIKLADKC
                     EKSKPVLKEILDSIDNYIYIVNPNTYELLFVNNKVSRLDLEIKLGETCYKSLLKSDRP
                     CNNCPLNGLEENKHSKFKIETNTFGKNISIASWINCIDGEYNCLIECIDSSLYKNK"
     gene            37919..38665
                     /locus_tag="ACGI5H_001871"
     CDS             37919..38665
                     /locus_tag="ACGI5H_001871"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889797.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdcF family protein"
                     /protein_id="HFG9697574.1"
                     /translation="MLNSITLILGIIFTIYYFYLKIVFGGISFSEIFLVVGIVLIIYQ
                     IFKKKIKEKKVFYRVLKIIISIFLIVFVVTESLIIFYPKNSLESKSDYLLILGASVKK
                     TTPSTTLKGRLDTALKYLKINDNCYVVVSGGKGSGEKITEAKAMKDYLIKNGIDKNRI
                     IEEDKSTNTYENFKYSKLKIEEHSQGKLSDLKVKIVTTDFHVLRSKILAYRNGYKNTS
                     FYASKSKLSFVPTYYTREFFALWKTIIFDR"
     gene            complement(38614..38922)
                     /locus_tag="ACGI5H_001872"
     CDS             complement(38614..38922)
                     /locus_tag="ACGI5H_001872"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889798.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxamine 5'-phosphate oxidase family
                     protein"
                     /protein_id="HFG9697575.1"
                     /translation="MNFFKENSTFYFATVEDNKPRVRPFGFIMDYEGKLYFGIVKYKT
                     SYKQLLVNPNVEISTTSKVGKWIRIKGIEKTRYEFISSLFIYYLSKMIVFHNAKNSLV
                     "
BASE COUNT        15774 a         3976 c         6717 g        12499 t
ORIGIN      
        1 actaaaagta agaaatgatt tttatatttt taaactttat tattggtaac ttatctgtaa
       61 atattttaaa atgtactata gaaagttgtt aaaaatatta aataattata ttaaatttaa
      121 gtgtgttttt tatgctataa ttagtatgta ttttttatga tatattttat aaaaaatata
      181 atttaatcat ttttgaggat attattatgt tagatgcatt tataacaatt gtttcttcta
      241 ttatagaaat atggtcatgt aaaaaagttt ttgattatac tagtcagtca aagaccgact
      301 taaaaaaact aaatatgtat tttctctttt ctgtttttct cattatttct tctttatata
      361 taaatatagg agctaatagt agaatcttga tatgtatatt tgtaatgttc gttttctata
      421 agtctaacta taaggttaat atatataaat gtctggtaat ctcatttttt tattggttaa
      481 tattaatagg tataaatgga ttaagtatgt tattagtagc aacagtaagc aatttggata
      541 atatgaatgt tttacttagt ggcagtttat atagatatga agcaatattc ttgggaaaga
      601 taatgttagg tatattactt tatgtttata aggcttcttt taaaaatttt aaaataagta
      661 aaaaagagat atacatatgt attcctatga tagcaaattt attgtcattt tttgtacttt
      721 atgattatat tattaatctt gtaaaaatct ctcctgaaag aagaactgct tttttagtaa
      781 tagttttact attaatatta tctaacattt caatctttgt attaatacat ataatactta
      841 agattaaaat taggaaaata agataaattt taatacgatt catttaaatt aaaagttaat
      901 aattactttt ttatgtataa ttttacatga atttctataa aagttatttt attaaagata
      961 gatatactta tatatacgga tataattaaa aaaagtcttt ttaactttaa aaattaatgt
     1021 taaaaaataa acttatacat taatattaat aataattatt taaatatctt aagtaaatca
     1081 gtcttacata tatttccgat agattatatt gataaaaaac actaaaatta aattaataaa
     1141 agtacttgga gggatggaaa tgaaagagga aaattttatt aatgttgaat acgaggataa
     1201 acgtttttca attaatagta aagaagtttt gtacatagaa aagcaagagt atgaagtaaa
     1261 gatttatact gaaagtggta attatgaagt tggagaaaat gctccttgta taagaaaact
     1321 attgaaagaa gaaaattttt tcaaatgcag taatagttat attgtaaatc tagacaagtg
     1381 tgaattttat ctcagcaata attgtatttt tgtgaataat aattttataa gaattttagg
     1441 ttcagaaaga aaaaagaaat taaaaaagaa attagaaaaa ttatatgatt atgaagatta
     1501 atattgggag gctgtatttt atacagcctc tttatttatt gattgtatta ttaataaatt
     1561 ttaaattatg ataaaatata aaacaagtaa cttatttcag aataaaatac tttttaaaag
     1621 aaagggacga gatatgggag attataataa aatgcttgaa ttaaagaata acttaggtat
     1681 cagtgaaaga aagttaaaat atccttgtat ctataaacat ttcaaaggga aatattatgc
     1741 tacaatgggt cttagcaagg ctattgatga tatagaaaac atatgtgaaa tatatggtaa
     1801 agaaaattta atccaaaaca gaaataaata taaattagtt attagacata ctgaaagaga
     1861 agaagatatc tatgtttata gggatttaga tggaaacttt tatcataaaa aagaagaaga
     1921 tactaatgat ttagttttat acaagacctt atatgatgat acaggaatat ttgcaagacc
     1981 tttggatatg tttttagaaa aagtagatac agataagtat gtcaattcaa ttcaagaata
     2041 cagatttgaa gaagtatata aataatataa gagaaatatg tttataaatt tagaaaaatt
     2101 ctttaacagt acaataattt gcagaaatac aaatgagatt tattgtaaat aatatgttag
     2161 attagattat aaaatagaaa caaagtaaag tattatatga tataattaag ttttgagaag
     2221 tgataattta tatttaataa aaaataggca tatattagga ggacatatgg gaaatacttt
     2281 ttatatagta agacatggac aaacggattg gaatatattg ggaaaaacac aaggtcatgg
     2341 taattctgac cttacgcctc aaggtataga acaggcaaaa gaactttctg aagatattgg
     2401 caagtattca attgattata tttttagtag cgaccttggg agagcaatgc aaacagctca
     2461 aattttagga gataagctca atattgaagt tcaaaaaact gaggcactta gagaaatggg
     2521 attcggagtt tgggaaggcc ttttaataaa agaaattcaa aaagattatt cagatatata
     2581 tgcaacatgg agaaatgaac cacacttagt aaatatacca gaaggcgaaa ctcttaagat
     2641 tataaaggaa agagtagatg cttttataaa ggaactaaat gaaaaatatg ataataaaaa
     2701 tataattctt gttacacatt caattacatt gagggttatg ttgttgtcat ttttagaatc
     2761 aggtatggaa aatatatata gaattaagca agataatact gctttaaata tagtagaatt
     2821 taaagattat gggcctgtta tagtaaaaat gaatgataca agtcatataa aaaatcatgt
     2881 aaagataaat aattctgcac tggagtagga atcaattata aggagaaatt tatgagtaaa
     2941 gttatagtag ttggtggagg agcttctgga atgatggcag ctttgtcagc ttcaaaaaac
     3001 aataatgaag taatattagt tgagagaaat ggagaattag gaagaaaact tagggcaact
     3061 ggtggcggta gatgcaattt taccaataat agagagatag aagatttttt tgataaagtt
     3121 gtcagtaata aaaaatttct ctatagtagt ttttatacat ttacaaataa agaccttatt
     3181 tcgtattttg aaagtagaaa tttggaatat aagattgaag aagaaaatga ccacaaagta
     3241 tacactaaaa atgataaatc tatagaagta atagaagtat taaataaaga tttactcaat
     3301 cacaatgtaa agataatgta taataagaaa gttatagata ttataactga agaaattgct
     3361 ctaaaagatg attctaataa ggacaagtca aagtatctaa taaaagggat tattttagat
     3421 aatggagata aaatactagg agacaaggtt attatatcaa ctggaggagt gagttattca
     3481 aagacgggtt cagatggttc aatgtataag attcttaaaa agcatggaca tacattaaac
     3541 aaactatatc ctgctttagt tccacttaca atagaggaaa aatggattaa agatttacaa
     3601 ggaatatcca tgaagaatgt ggaaatatct tgtaagatta agaaaaggaa aatatcaaaa
     3661 tctggagaca tgctatttgc ccattttggg ataacaggac cttgtgttct tataatgtct
     3721 tcttatatta acaagattat tgaaaaggaa aaggtagaat taaatataga tttcttacca
     3781 aatttaagta ctgatgaaat ctctagtata atcagagcat ttccaaataa aaatgttcta
     3841 aataatctta agcaaatact acctcaaaat ttcttaaaag agattttttc tctattatct
     3901 ttagttgata aaaaggcaag tgatttgtct aaggcagatg aaattagaat tattgagtat
     3961 ataaaaaata tgaagctaac ttgtaatggg actacaggta taaacactgg tatggttact
     4021 tctggtggta tttcagttaa agaaattaat tcttctacta tggaatctaa attagttaag
     4081 aacttatttt ttacaggtga agtaattgat atagatgcag aaactggtgg atataattta
     4141 caaatagcat tttcaactgg atatcttgcg ggtataagtg tataaatata attttttaat
     4201 aattaaatat gaataaatag aggtgtatat atgggtaatt tagttatagc tgtagatggt
     4261 ccagcaggag ctggaaaaag tacaatagcc aagatagtag caaaaaagct aaatataaat
     4321 tatatagata caggtgctat gtacagagca gttacttata agtgtttaaa aagtggtatt
     4381 gatgtcaata atgaaaaaga agttattcaa atagctgaaa attcggatat agattttaaa
     4441 gataacaata tatatttgga caaagaagtt ataaatgaag aaataagaac aatagaagta
     4501 agcaataatg tttctaatgt agcaaaaata aaagaagtaa gacagttgat ggttgaagtt
     4561 caacgaaaaa taggaatgaa aaattcagta atactagatg gtagagatat aggttcatat
     4621 gttttcccag atgcagatta caaattcttt ttagtagcta ctccagaaga aagaggaaat
     4681 agacgctata aagaactttg taataaagga tataatacta ctttagaaga agtaattgag
     4741 gatataataa gacgagatga aattgattca aatagagaat ttgcaccatt ggtaaaagct
     4801 aatgatgcac tagaaataga tactacagga aaaactatag aagaagttgt agaagaagtt
     4861 gtatctaaaa taaatcttta gttttttatg catcataatg aaaataaatg tagtgttgaa
     4921 gggagataaa cgtgaatttt tatagatttg taataaatat ttttaagggt ttttctaaaa
     4981 tattttttaa atatgaagtt ataggtgcag agaatattcc agatagagga aatatagtaa
     5041 tagcatcaaa tcataaatcg aatcttgacc ctatattctt ggctgctgcc atagaaaata
     5101 gagaaatagc tgcaattgca aagaaagaat tgtttaaagt aaaaccattg ggatttatat
     5161 taaaaaaatt gcatgttatg cctataaata gagaaaaacc agatgtatct acaataaaaa
     5221 ctattttaag gtcagttaga gacggttatg tattaggaat atttccagag ggtactagaa
     5281 taaaaggaga ttcttttggt aaggctaagg caggtctttc tgtatttaca ataaaaagta
     5341 aatctaaagt tgttccagta tcaataatat ctaaatataa actttttagt aaagtaattg
     5401 tatatattgg agaaccaata tcatttgaag aacattttaa ggaaaaattg agtaatgatg
     5461 accatgaaag gatatcacaa gagattttag aagtgataaa acaaaattac tttaaatatt
     5521 caaaataagg gggtaaagtt atgaacataa aaatagcaaa aaatgctggc ttttgttttg
     5581 gagtaaaaag agcaatgaaa atggcatggg atgaagttga aaaaaatgat tctggcatat
     5641 atgctttagg tcctcttatt cataacaagc aagcagtagc aaaatatgaa gaaaaaggtc
     5701 ttaagactgt gaatgaaatt gatacaatac caaatcatga aaatatgata ataaggtctc
     5761 atggagttcc tgaaaatata tataaggaag ccaaagataa aaaattaaaa attgtggata
     5821 ctacatgtcc atttgtaaag aaaatacata cagtagtaag tgaatatcat aataaaggct
     5881 atgaaataat agttattgga gatatgaagc atccagaagt tataggtata aatggatggt
     5941 gtgaaaattc agctataata ataaagacct tagaacaaat ggaaaatatg gaatttgata
     6001 actccaaaag atattgtctt gttgcacaga ctacaataaa tccagagttg tatataagta
     6061 tagttaataa actatcagat aaattagaag aaatagtatt taatgataca atttgttcag
     6121 ctacaaaaac aagacaagaa tcagctaaag agttagctaa agaagttgat tgtatgatag
     6181 ttataggagg taaacacagt tcaaatactc aaaagttagt aaaggtttgt gaagacttag
     6241 taccaacttt tgcaatagag actaaagatg aattggatgt aaatacgctt aaaaaatata
     6301 aaaatttggg tattacagca ggggcatcta cacctaattg gataatagaa gaagttgtaa
     6361 cattccttga aaatttataa tttgataggt aataaaaata ggtggacatt gttataattt
     6421 atcataatat ccacctttga tttcatatta catgtggtaa atagataacc taatatcaaa
     6481 aagtgtgtat cttaagatga aaaactaaga gtataagatg cgcacttttt aatattagaa
     6541 attcaaaaga aatattgata ttgattatca atagaaaata gaatataata taattgttgc
     6601 aaaattagtc taggaggtaa attaatggaa atgttgatat ccgcttctga agaggcgttt
     6661 ttacatgtag gttctatgat tggatttttt attttgttat ttggatatat taattataaa
     6721 actagtggaa attttactaa tatcatatca aaaaacagaa aatttcaacc cttaataggt
     6781 gctttaattg gagctatacc aggttgtggc ggaagtttgg caataatgcc attgtatata
     6841 aatggaaaat taagctttgg agcaataatt gcaagtttaa tagctagtat gggagatgca
     6901 gcatttgtac ttatttcatc aaatattaaa atgtattttt ttgtcactat agttagtaca
     6961 attacaggaa taataactgg acaattagtg gattacttta aactagaaga aaaattaggg
     7021 ttaaaaaacc gtagaaaatc agataaatat gatataagta aaaataaccc taaagaaaat
     7081 aaagaacaac ataatcatga tgaaataatt ttagacactc tagctaaatc tcatggaaat
     7141 acaaatagac ttgcatttat aataacacat ggaaagggat ataaaattta tataggaatt
     7201 atagtaatcg gttttatatt tatgtcactt gctcactctg gacttaatct tcctataatt
     7261 gagaagttac attcattgga agaagtaata gcagtgattg gaatattatt ttcaataatt
     7321 tatatgtggt gttttaaaaa ggtatttaaa aattctaatc aaaaagagga agaaaataaa
     7381 aagatttctt tgcgagaaat gcttatccat tctgttggag aaatatcatt tgtaattaca
     7441 tggattttta ttgcatatct tatttacgat ttgataatat taattttagg tggagatgaa
     7501 tacttagtta aattagtatt atcaacaggt gtaataagtg tatttatagg tgcaggtctt
     7561 ggacttattc caggttgtgg gatacaaatt gtgcttatgt cattttattt gaagggaact
     7621 ataccacttg gtgcagtgat agccaactct atttctcaag atggagatgc acttttccca
     7681 cttttagcaa tggataaaaa atcttcttta tgggctatga ttattactac tataccagca
     7741 atacttgtag gtatgatagt ttatgcattt ttaggttaaa tataattatg aataaagaag
     7801 tattaaaaaa ataataaagc acataaattt atttataaga atagtgaaga ttaaatataa
     7861 aaataaaaaa ttcaatatga attaaattat tgcttaaata ttaatgagaa catgggagat
     7921 aatattattc ctcatgttct ctctatttaa ttaaaggaat tatggaacaa atttcaagtg
     7981 atactttcta tcaaaactca tatataatat atattaataa attaaactat aatacgtaat
     8041 acagtcagta tattgatata aaaaacttag gaggagttgt aaaaatgggt aatttaaaaa
     8101 gacagtgtga tgtttcaagt ggaagagaaa aagctgacat tgtactaaaa aatgggacaa
     8161 tcataaatgt atttacagaa gagttaataa caggagatgt agcaatagta ggagacacta
     8221 ttgttggaat tggcgattac aagggcaatg tagaaattga ttgtagtaac aaatatatat
     8281 cacctggctt tattgatgca catatgcata ttgaatctac aatggtaatg ccaattgaat
     8341 tatcgaaaaa attattaaaa tcaggtacga caactatcat agccgaccca catgagttgg
     8401 tcaatgtaaa aggagttagt gcaatagatt ttttattaga atcgacaaaa gatataccac
     8461 ttaatgtata tattatggtg ccttcatccg tacctgcaac aagttttgaa actaatggag
     8521 ttggtaaatt tagtgcaaaa gacatggaga gttatgtaaa taatcctaga attttaggtt
     8581 taggagaggt aatgtgtttt aatgatgtta taaattctga aaatgaaatc ttggataaac
     8641 tagagctttt taaaaataaa gttgtagatg gacatgcacc taatataaat ggtaaatcac
     8701 ttcagacata tgtatgtgca ggaatagaaa atgaccatga atgtataact tttgatgaag
     8761 tatatgaaaa attgagagca ggattaaaaa ttttaataag agaaggaagc gcagcaaaaa
     8821 atttaaagtc tatagtaagt ggtatgctaa agcataactt gccaattgaa gaatttatgt
     8881 tttgcacaga tgataagcac ttagatgata tagaaaaaca aggtcacata agatggaata
     8941 taaaatgtgc gattgattta ggtatggaac ctgttagggc tataaaagtt gcaacttata
     9001 attctgcaaa agcatatggg ttaaggaaaa ttggagcaat aggtgcgggt tataaggcag
     9061 atattgttgt attgaatgat ttagacaaaa tggaagtgga tagtgtatat aaagatggta
     9121 atttggtaaa cgaagagatg ttttctaatt acaattatga gattaaagat aaagaattgc
     9181 ttaatacagt caagtttaaa tatattaata aagaaaaaat acagttaaaa gtaagtgaaa
     9241 aaaattatgt aatggagatt gtaccttatc aaattttgac aaataaggta tatgaatctt
     9301 taccatgtgc agatggatat tttgttccaa ataaagagta ttcaaaactt tgtgttgttg
     9361 agagacatag aatgactgga aatgtagcaa ttgctccact aaaaggattt ggcataaaaa
     9421 atggagcaat tgctactact gtggcccatg attctcataa tattatagtt gcaggggata
     9481 atgatgatga tattctagta gctataaatt acttaaagga aatacaaggt ggttatgtaa
     9541 ttgtatcaaa tggaaaagtt cttgcacacc taagtcttca agtagctgga ttaattagta
     9601 cttttacagc tgaagaagta caagaaatta ctgataatat gttggagata gcaagaaaaa
     9661 tggaagttcc agagtatgta gaccctttta ttacactttc ttttatggca cttccagttg
     9721 ttccacaaat aagacttaca gatttaggtc tatttgatgt tgaggaattt aaatttatat
     9781 agatagtata aaagtaataa taaatgaggc tttctcaaaa tagagataag tctcttttta
     9841 ttgttgaaat gatgaaaata tatttgattt catacaaaaa agagcatctc atgaactaaa
     9901 aattttattt ttagatatcc ttattttaat taatctatca tttaacattg ttttaagcat
     9961 agatatctta ataaaactat tttcagtcta ttttaacata taaatacatg aaaattatat
    10021 atttatgaaa ctttatacat aaaaaataaa atattttatt tatatataga tttatagggt
    10081 aataatataa gcatagtata aaattattaa taaaaacaaa aggagagata tttatgttga
    10141 gtataggaac aaaagcacca gaatttacac tagaagataa agatggaaat aaggtaagta
    10201 tgtcagattt taaaggcaaa aaagtagtag tatattttta tcctaaagat aatacaccag
    10261 gatgtacacg tcaagcttgt gcttttagaa atgcatatga tggatttaaa aaggaagata
    10321 tacaagttat tgggataagt aaagatagta taaaatcaca tcaaaaattt gcagaaaagc
    10381 atgaacttcc ttttatttta ctttctgacc ctgacttagt tgctataaaa gcttttgatg
    10441 tatggaaaga gaaaaaaatg tatggaaaaa ctgcattggg agttgtacgt gcgacatata
    10501 ttatagatga aaatggaatt attgaaaaag tctttgaaaa agcaaaacca gacacaaatg
    10561 cacaagagat tcttgaatat ttggaaaaac aggagtaata agaatttatg attataatgt
    10621 tatcaccagc taaaaatatg aagaatatag aagtatttga tagagatttg agtttgcctt
    10681 gctttataga taacacaaaa gaaatagtgg aaaatataaa gacatttggt atagaagatt
    10741 ttaaaaataa aatgaaaatt aatgaaaaat tagctgtatt aaataaaaat agatttgaaa
    10801 gcattaaatt tgatagatta ggaaaccctg caatcttaac ttatgatgga atacaatata
    10861 aaaatataga agcagaaaat tttacaagga aagatgaaga gtttgcaaat agctgtattc
    10921 gaatcataag tggattgtat ggtgttgtaa aaccatatga tagtatatat gaatatagat
    10981 tagaaatgca gacaaaatta caagtaggtg agtttaagaa tttatacgaa tattggggaa
    11041 atcgtatata taaagaacta atcaaagaaa aaacagctat cgttaatctt tcatcaaatg
    11101 aatacagcaa atccatagaa aaatttatta aagatagtga tacatatatt acatgtactt
    11161 ttaaagtaaa taaaaatggc atattgaaag tggaatctac acaagcaaag aaagctagag
    11221 gtatgatgac aaaatacatt gtaaaaaata ggataagaga tattgaagaa ctgaaaaagt
    11281 ttgatttaga aggttataag tataaagaaa acttatctaa caatagtgaa tacatatttg
    11341 taaaagagta gaagttttgt taaatattaa atggcattgt taaatttagg taaaatatac
    11401 ttagtgtgta ttgaattgaa cttgatttta aaatataatt attcttaaat taaaaaaaga
    11461 aaggagtggt cttccaaaat ggaaaatcac aaacagatgc cttggcattc aagagcaacg
    11521 catgaaattt tagaaagtct agattcatca gaggaggggc tcaccgatac cgaggcggaa
    11581 aaacggctta aagagaatgg cttaaatgaa cttagaaaaa aaccacctag aacaacttta
    11641 caaatgcttt ggagtcaaat tacagatgct atggttatga tactaatagg agcagcaata
    11701 ttatctttga tatttggcga atttacagaa gcttttgtaa tactaataat tgtaacagta
    11761 aatgcagtta ttggaattgt tcaagagaaa aaagcagaat catcattaga agcattaaaa
    11821 aatatgaatt cacctacagc tcgtgttatg cgtgatggtg aagaaaatgt tattccagca
    11881 agtaatcttg tagtaggaga tattgttttt ttagaagatg gagctatggt tccagcagac
    11941 cttcgtttaa tagaaacatc aagtttaaaa attcaagagg cttctttaac aggagaatct
    12001 gttccatcag aaaaagatgc agatacaatc ttacctaaag aatgtgtatt aggagaccgt
    12061 agcaatatgg cgtatacatc ttcaatagtc acatatggta gaggtgtagg tgttgtagta
    12121 gcaactggta tggatacaga agtgggtaac atagcacatc ttttagattc acaagatgat
    12181 tttgatactc ctataaaacg taaacttaat actgttggaa agacattaag tgtcataggt
    12241 attattgtat gcgttgttat atttgcaata ggtgcatttt atcagagacc tctcttgcca
    12301 atgtttatga ttgcaatttc ccttgccata tcaattattc cagagggatt acctgcaaca
    12361 gctactattg taatggcttt aggcgtacag cgtatggcta aaagaaatgc tttaattaga
    12421 aaattacctg ctgttgaaac attaggagga gctacagtaa tatgttgtga taaaactggt
    12481 acattaacct taaataaaat gactgttaca catattgctg tcaatggaga ttttgaatct
    12541 ggaaaagtga catcaataga tactgcatct gaaaaacatc cattagtgta taaagagatt
    12601 gtttatgctg gtgcactttg taatgatgca tgtattaatc cagataaaac agatgaaata
    12661 ttaggtgacc caacagaggg cgcattaatt tttatggcca aaaaatttgg aatagatcaa
    12721 gaagctcttg aagaagaata tccacgtgta tttgaacagc cttttgattc agatagaaaa
    12781 tgtatgacaa ctgttcataa tatagatgaa aagattattg cttatactaa aggagcagta
    12841 gacgaaattc ttgacctatg tactaaaata ttaacttcaa aaggtgaaag aaacattact
    12901 gaagtggata aaaagaatat acacgaatta tgtcttaaca tgtctaaaga tgcattgcgt
    12961 gtacttggtt ttgctaagcg tgagatttca tctataccaa aagaagatag tgaaaatata
    13021 gaatatgatt taacatttat aggtatggtt ggtatgattg acccaccaag aactgaggta
    13081 attgatgcag taagtacttg taaagaagca ggtataagaa ccataatgat aacaggtgac
    13141 cataaagtta ctgccacaac aatcgctcat gagttaggaa tatggagtga agaaaatact
    13201 gtgatatctg gtgatgaact tgataatttg agtgatgatg aactagatga agctgttaaa
    13261 aatactacag tatttgctcg tgtatcccca tttgataaac ttagaattat acaatctcta
    13321 aaaagaattg gagaagtacc agcaatgact ggggatggtg taaatgactc tcctgcctta
    13381 aagtctgctg atattggtat agccatgggt ataagtggta cagatgttgc aaaagattct
    13441 tctgacatga ttttaatgga cgatagtttt acaacaattg cttatgcaat aaaagaaggt
    13501 agacgtgtat atagaaacat acaaaaagtt atacaatttt tgcttgttgg taatatagca
    13561 gagatactta cgttgtttgt agcaatatta ttaaattggg atactccgct tcttgctgtt
    13621 catattctat gggtaaacct tgcaactgct acgcttccag cccttgctct tggagttgac
    13681 ccaccaagca gaaatataat gaagcaccag ccagtgaaat caaccacttt gtttgaaaaa
    13741 aatcttatac aaagagttgt tacccaaggt atatttgtgg caataatgac tattttagca
    13801 tataaaattg gtcttaatat agaaaatcat tctgtaggtc aaacaatggc attttgtgta
    13861 ttagcatttt cacagatgtt acgagcattt agtcagcgtt caaatacaga ttcaatgttt
    13921 aatagaaata atggtaaaaa tccatttctt ttaatctcat ttttaacttc tgcattttta
    13981 atagcagtaa tactatttgt acctgttttt agaaatgctt ttaacttaac agttttaaat
    14041 aacttagagt ggcttgtaac gattgtttta gccataatgt ctgtaattca agtagaggtt
    14101 gggaaaatta ttaaaagaaa aaaattaaaa aaatagttga caaaattagg aaaaatatat
    14161 aagatataaa acatagaaaa attaaataaa tcttatccag agaggtggag ggactggccc
    14221 tatgaaaccc ggcaaccagt atatttatat acattggtgc taaatcctgc ggcgaaagct
    14281 gagagatgag tataattaag cttatacaga gcctgagtta tatactcagg ctttatttat
    14341 tttaactctc atctggtaaa tagtttaatt ttttttacta aaatctaagg gggatacaag
    14401 aatgtataat aaagaaacaa tatgtgtgca aggaaattat aaaccaggta atggagaacc
    14461 aagagtacta cctttatatc aaagtacaac ttttaaatat agcagtatag accaacttgc
    14521 tgaattattt gatttaaaag ttgatggaca tatatattca agaataagca atcctactat
    14581 tcaagctttt gaagaaaaaa taagtttact agagggtgga gtatcttctg tagctgtatc
    14641 atcagggcaa tctgcaaata tgttggcagt tttaaatata tgtaaatcag gagatagtat
    14701 actttgttct tcaaaagtat atggaggaac attcaattta ctaggaccta gtcttaaaaa
    14761 atttggtata gatttaatat cgtttgactt agattcaagt gaagatgaga tagtagaact
    14821 tgcaaaggaa aatactaagg ttgtgtttgc agaaacactt gcaaatccaa ctcttgaagt
    14881 catagatttt gaaaaaatag caaatgtagc taagagaatt aatgttccat ttattgttga
    14941 taattcatta gcatctccag tgctttgtaa ccctttaaag tatggagcaa atatagttac
    15001 tcattctacc acaaaatatt tagatgggca tgcttcaagt gttggaggaa ttatagtgga
    15061 tggtggaaac tttaactggg ataatggaaa atttccagaa ttagttgagc cagacccaac
    15121 atatcatggt ataagctata ctcaaaaatt tggaaatgcc gcatatgcaa ctaaagcaag
    15181 agttcagttg cttagagact atggaaattg tttaagccca ttcaatgcgt atcttactaa
    15241 tttaaatgtt gaaacactac atcttagaat ggagagacat agtgaaaatg cacttaaaat
    15301 agctagattt ttagaaaaac atgaaaatgt agattggatt aattacccag gacttgaaga
    15361 taacaagtat tatgagaatg ccaaaaagta tttatcaaga ggatgtagtg gtgttttatc
    15421 atttggagta agaggtgggt tagaaaatgc caaaaaattt gtggaaaaat tacagatagc
    15481 atctttggtt acacatgttt cagatgtaag aacttgtgtt atacatccag cttcaactac
    15541 tcatagacaa ttaacagaag aacaattaat tgcatctgga gtattgcctt cactaataag
    15601 attatctgtt ggaatagaaa atgtagagga tttaatagct gatttaaatc aagctttaaa
    15661 tttctaatat tctaagagaa agagaagtga aaagatatgg ctttaatact accaaaggga
    15721 ttacctgtta ttaataaatt attagatgaa ggaatagatg taatttataa agaagatttt
    15781 aaaaaggaat taaagtatga agaaaacata gacactaaga tagctatact aaatctaatg
    15841 cctataaaga tagatacaga attagattta ctaagaagga tagataaaac aggattcaac
    15901 gtgtctgtgg aatttattaa aatttcaaca agagaaagta aaagaagttg taatgaatat
    15961 gttaaagaat tttataaaac atttgatgaa gccaaaggag agtattttga tggctttata
    16021 ataacaggag ctccagttga acaaatggag tttgaagaag ttgattattg gaatgaacta
    16081 gaagaaatta tggattattc taagagaaaa actaaatcta cattatatat atgttgggca
    16141 gctcaagcaa gtctttacaa atactacaat gtaaaaaaac ttccactaag tcaaaaatgt
    16201 tttggagtat ttaagcataa ggtagataaa gatagtaaaa tagtagatgg atttgaaaat
    16261 gaattttttg ctccacattc aagacatact actgtaaata ttgaagcttt gaaagagaat
    16321 aaagagttga gcattgtgag tcattctaaa gaagctggtc cctatataat tacaaattca
    16381 agagatgtgt tcgtaatggg tcatagcgag tatgacaaat acactcttga taaagaatat
    16441 aagagggata taaataaagg agataaaata tctatacctc aaaattacta tattaatgat
    16501 gacccttcag aagagccaac tgtaaaatgg aaaaaacatt cagaattgtt gtttagaaat
    16561 tggataaaaa actatttgat acaataaatt ttaagagtat ataaatgtta actaaaaaaa
    16621 tatagaaatt tataggtata aagttaatct taatgatact ttatacctta tttttttaaa
    16681 atttgacctt ataatagtag ttttatattt taagaaaatc actttaggtg tatgtagata
    16741 gaggtggctt taattttata tatggtgcga taatgggaga ctaaaccttt atagtatcaa
    16801 taaatttgta ttttaacttt taaaagagat taaaaaggga gaaatcagtg taaaatatat
    16861 atatagattt tttattaaat tttattaaaa atatcctgta taaaattaaa tatcaataag
    16921 ataacaaaat ttcaattgaa gttacaatat tgtaattgac aataaatact taatactata
    16981 atatttaata cattaaacat tatagtgtta agtatttatt tacagtatgc acttcagcct
    17041 aaatttgaaa taaagtattt tcgtagggag cgtttgtatg gatgagatga gttttaagaa
    17101 agagctacta gagttgacta gagatataaa tatgaaattt acaactttat taagtgattt
    17161 ttatcagcca cttggtatta cagcagtgca agctttgatt ttatctgagt tatgtgaaca
    17221 tggagagaaa aaaataagcg atttagggaa gaacttaaac atgacaaata gtaatgtatc
    17281 agtaatctgt caaaggcttg aaaaaaatgg ctttttaaat cgcataagag atatagaaga
    17341 ccaacgaatt gtaaaagtaa aagttacaaa taaatcattg gatatacaag aacatatttc
    17401 aagtagtatt tttgatagtt attttgaaaa tatgaccagt gaaaaattgc aagatatgga
    17461 agatataata gaaggtttag agaaattaaa taaactttta acttacattg attgcaaata
    17521 acataaaaat aatttaaagg agaataaaat tatggatgaa cataaacccc aaaaaaggtc
    17581 agcactctat tattatacag ttataataat agtagtaatg tttttaaatg ctttaatatt
    17641 tccaagttta atggataaaa aaatggttga gattgactat ggaaagtttc tcacaatgtt
    17701 ggatacagga aaggttaaat ctgttgagat agaaaataat agaatagcaa taaatccatc
    17761 tagtagcaag gataagaata tatacataac tggtagaatg gatgacccag aattggtaga
    17821 tagactaaaa aatgcaaaag tagaatttac taaggttatt cctaaggaaa attcacctct
    17881 tttaagtatt ttacttacat ggataatacc tataggtatt cttatgctat ttggtaactt
    17941 aatgatgaag tctatgcaaa agcgaatggg tggtaatgct atgcaatttg gaaaaagcaa
    18001 cgccaaaatg tatgtatctg ctcaaagtgg aaaaagattt aatgatgtag ctggtcaaga
    18061 tgaggcaaaa gaagctttaa ctgaaatagt agatttctta cacaatccag aaaagtataa
    18121 aaagatagga gcacaaatgc ctaaaggagc acttttagta ggacctccag gtacaggaaa
    18181 aacactcctt gcaaaagctg tagcaggtga agcaaatgta ccatttttct caatatctgg
    18241 ttctgagttt gttgagatgt ttgtaggaat gggagcttct aggattcgtg atttatttaa
    18301 acaagcaaaa gaaaaagctc catgtatagt gtttatagat gagattgata ctattggtaa
    18361 aaagcgtgat aatggaagtg gattaggtgg aaatgatgaa cgtgaacaaa ctttaaatca
    18421 gttgttaagt gagatggatg gttttgatgg tggaattgga gtagtaatac ttgctgctac
    18481 aaatagacct gacagtcttg acaaagcatt acttcgtcca ggaagatttg atagacgtat
    18541 accagttgaa cttccagacc ttggaggacg tgaagctata ttaaaggtac atgctcaaaa
    18601 tgtaaatgta agctcagata tagattataa tgcaattgca aggtctacat caggagcatc
    18661 aggtgcagaa cttgcaaata ttgtaaacga agcagcactt ttagcagtta agtctggcag
    18721 agatatagta gaacaacagg attttgatga atctgttgaa actgtaattg ctgggtatca
    18781 acgtaaagga gctgtaattt cagataagga aaagaaaatt atagcatatc atgaaatagg
    18841 tcatgcactt gttgctgcta tgcaaaaaca ttctgcacct gtccataaga ttactataat
    18901 acctagaact tcaggagcat tgggatatac tatgcaagtt gctgaagatg agagtgtact
    18961 tatgtctaaa gaagaagcaa ttgataaaat aactactttt acaggtggtc gtgctgctga
    19021 agaggttatc tttaacactt gtacatcagg agcatcaaat gatatagaac aagctactaa
    19081 aattgcaaga gctatggtta ctcgccttgg tatgagtgaa gagtttgata tggtcgctct
    19141 tgaaactgta agcaatcaat atttaggagg agatacttct cttgcttgtt cttccgacac
    19201 tgctgctaaa atagatgaag aggtatttaa aatagtaaag gcttgtcaca aaaatgcaat
    19261 tgaaatctta gaaaataata ttgataaatt gcatgaactt gctaattatt tattagaaaa
    19321 agaaactatt acaggtgatg agtttatgga aatacttaac ttaaactaaa atgattatac
    19381 acaagataaa aatgcctatt gttaggcatt tttattttac aactaaattt tttaaattta
    19441 tatttaaatc tttacataat cttaatcatt aaaaatacat cttaactaca attttatatc
    19501 ggaattgata ttataatagt aatgaatggt gtaaggaggt tttttaatgg atagacctaa
    19561 tcctgatatt ctattagaaa aaattaaaaa tgaagaagaa aaactaagta gaggtcaatt
    19621 aaaaatattc tttggttatg cagctggagt aggaaaaacc tactctatgt tggaatctgc
    19681 acaaaattta aaaaaagtgg gtgtagatgt agtagttgga tatattgaac cacacactag
    19741 accagaaaca ttggctttac ttgatggctt ggaaattctt cctgtaaagg agatagaata
    19801 taaatctata aaactaaaag aatttgattt agatgctgct ttagcaagaa aaccagaagt
    19861 tatattagta gatgaatttg cccattctaa tgttgctggg ttaaggcata caaaaagatg
    19921 gcaagatata gaagaattgc tgttagcagg cataaatgtc tacactactg taaatgtaca
    19981 acatttagaa agtctaaatg acattgttga gataattaca aacgtatcag ttaaagagac
    20041 tataccagat aagtttttgg atacaaatac acagttagaa cttatagatg ttgaacctga
    20101 tgtacttctt gaaaggttca atgaaggtaa gatatataag aaagaacaag ctactagagc
    20161 aaaaaataat ttttttataa aagataacct ggttgcactt agagaaattg cacttagaaa
    20221 aacagcagag agagttaata aagaagttca aatgaccaga ctatcaaagg gtgatgtaac
    20281 tgtaatacct acatcagata cacttcttgc atgtataagt ccatctccat cttcagcaaa
    20341 agttattaga actgcatcca gaatatcaga cagtacattt gcaaaatgga tagctttata
    20401 tgttgaaact ccaaacacag caagacttcc atttgatgaa caaaaacaac tacaaaataa
    20461 cctaaaatta gctaagaaat taggtggaga aataattgtt ttacatggtg aaaatataat
    20521 agagcaaata cttagaattg caaagctgag aaatgtaaca aaaattgtaa taggtagaaa
    20581 tcattcaagt aataaaagat ttagtaaaag atttaaaaaa gatatagttg acaaattaat
    20641 tgatgaagtt gattatatag atatacatat aattccatat aaatttgcct cagatgttaa
    20701 atacaaacct aaaaaggata aatcatcaat aaaatctaaa tttaaaatta gcaaagttga
    20761 ttttataaaa cttatattta ttactttgat gataagtatt ttagcatatg cagtacaaag
    20821 catgggattt ataagagaaa atatattgtt aatatatatg ttgggtgtag ttttagtttc
    20881 tatgtggact aaagggtata gtacaggtat aataagttct gtatttaata tagttctttt
    20941 aaattatttt tttacagcac cattatatac attatctata gcagattcaa actatatagt
    21001 aacactggtt gtattctcaa tagtaggtat aataactagc actcttacgt ctaagataca
    21061 gcatgaagca gaaactgctg ctaaaagaga agaaaataca aaaatgatat atcaaataat
    21121 taagggattt ttaagattat caaataaaga tgatatagta aacaaaggta tagaactttt
    21181 gtctcttagc ttaagtagag atgtaatttg ttatttaaat gtagataagc ataataaatc
    21241 aaagctttac aaaaaaaata ctaataataa ggataaaaat gatttggata gtgaagatga
    21301 aaaagctgtt gcaagttggg ttttatccaa ttcaacagta gcaggaaatg acacggatac
    21361 acttcctggt tcaaagggat actatatacc aattgtagga atgaatttaa ctttaggagt
    21421 agtgggaata tcatgtattg attcaaaatt ggatacagaa gatataagct taattgaaac
    21481 aataattgct caaatggcaa tagcgcttga tagagaaatc ttgtcagaag ctaaagaaaa
    21541 taccaatctt gagattgaaa gggaaagatt aagaagtaat cttttaagag cagtttcgca
    21601 tgaccttaga actccactag caggaatatc tggtgcagta agtacaatta taaaaaacaa
    21661 gggtactata ggtcaagata taatagatga attacttagt ggtgtatatg aagatactca
    21721 gtggttaata agacttgttg aaaatttact tagtatgacc aagatagatg aagggaaatt
    21781 ggaagttaaa aaacattctg aactggttga ggaaattata tcagaagcgt tacaaaaaat
    21841 aaaaaaaaga attgaaaatg cacttataga tattaatata ccagaacaga tattatttgt
    21901 tcctatggat gcaaaattaa tagaacaagt tttaattaat ttaatagata attctttgaa
    21961 atattcaaag gaagattgta agatagagat aaatgtatat gagaaagatg attatgtttg
    22021 gtttgaagta tctgataatg gtcctggtat atcaaaggaa cttaaaaagc atatctttga
    22081 cagatttttt actggagaag aaggagctaa agattccaga aagggtgttg gacttggatt
    22141 atcaatttgt aaatctataa ttcaagctca taaaggtgaa attatggtag aaaacaataa
    22201 agataagggt tcaactttta agtttagttt gcctaaggaa aatgaatagt tttaaatttt
    22261 aaaattagtt ttggaggaag aaatgagtaa aaaacttata ttgttagtag aggatgataa
    22321 gacaataaga aaatttatat ctactgcact tttaacacag gattatgatg tcaaggaggc
    22381 tataactgga aaagaaggta tatctatagc tgtctcatat tctccagatg ttgttctttt
    22441 agatttaggc ttagaagata tggatggaat agaggtaata aaagctatca gacaattttc
    22501 aaatatacca ataattgtag tttcagctag agagcaagat agagacaagg tagaagtatt
    22561 tgatgcaggg gcagatgatt acttaacaaa accattctcc atagtagagt tattagcaag
    22621 agtaagagta gcatttagac attcacaagt agaagctcaa caaaaagatg atgttaaatc
    22681 tacgtttgaa gtagataaat tattgattga ttttgataaa agaaaagtta ttgttgatga
    22741 tgttgaagtc catttgacac ctattgaata taatattctt tcattacttg caaagtatca
    22801 tggaaaagtg cttactcata attttataat aaaagaaata tggggtagtg ttatagggaa
    22861 tgagactaag tctttaaggg tctttatggc aacgttaaga cgaaaaatag aaaaacaacc
    22921 tgcaaaccca agatatataa ttacagaagt tggtgtagga tacagattaa atgatgaata
    22981 gttgtaatat attaattatt agattatgtg cttattaata tatattaaaa ttatatagtt
    23041 tagttaaaat aagaatgaag tgtatgtgct tgttgtcagt ttagcacatg cattttattt
    23101 tttagctttt ttagtatcaa taatttttta gtatcaataa tatgaaatat gttttaaaat
    23161 aagtatatag tgtaatatgt aataaaaact ttggttaaat aataaatgta tttaacactt
    23221 accttataat aaatttaata taaatattaa ataataatta ttaaaatagt gtaaaataat
    23281 tacagtaagg attataaaaa atttttagaa tgtaaattga aatttaggag tagatgtatg
    23341 tatatactga atttaaatac aagagagact attgaagatt ttagagataa attttatgta
    23401 gcagaaaatt cttatcttat attaagtgct ccaaaaaatt taaaattgct taaggaaact
    23461 ttggatatag atgaaataac ttttaatgat tgtcttaaat ttgatgaaat aaccaaactt
    23521 gatttatttg ataattacga ttttttaagc ctaaatacat ttgaactaag agatggagaa
    23581 gctgttatag aagaggtaaa tatgtattta tcagataatt ttatattggt tgtagtgaat
    23641 gaagaacact ttttatttga atttgtaaaa aatattattt tgaagaactc tcaacttgaa
    23701 aaaaatccag ttattaatct atttaagata aactacttga ttcttagaga agttataaaa
    23761 aatggttttg agtctttgga aaaagttgaa gagttaattc ttcaaataga agatgaaatg
    23821 atggacaaca ttaataagaa tcatgtatct agaataagtg atgtaagagg attaacaaga
    23881 attatagtta agaatactag acctcttttg tatattgggg atagaatagt taaggaaaat
    23941 ataagatatt taaaatattc aaatgtaaaa aaatataatt tagaaaattt tcaaggtata
    24001 gattttggaa ttgacaaatt atacaatttc gcattgtcaa cacgagagtt agcagataaa
    24061 ttattagata tttattcttc cagagtaggt gagaaaacaa ataacttaat tacaaaatta
    24121 accttgttaa cagccatatc agcaccactt acaattataa ctggtatata tggaatgaac
    24181 tttagatata tgccagaatt aaactggatt tatggatatc cagcaacttt attttttatg
    24241 ctatgtataa tttttgttgg aattataata tttaaaataa aaaaattatt gtaaattaca
    24301 gatgatgttt aattgatttt ataaaaatac atcaattgag aagctgattt aagtaaataa
    24361 aaaaatattt taaattgaaa atatttatag aaaatattga caattatatt ttctttgtta
    24421 taattattaa acaagaagaa taataaatta taaaaatgga ggataatact atgaaaggaa
    24481 tattaaaaga actaacagca aaactttata gcttttttta ctttatgttc tggggctttt
    24541 attttagcgc tggctatttc ttttacaaaa atatatgtac ttcctttctg gtgaggcctt
    24601 attttagtga ttttgagcat aagtaaattt tataaaaatg attattttat atatttatat
    24661 aagatttagt gcttgataga ttattttaga gaactcatta gtgagttctc ttttttattt
    24721 taaatataaa attataatat tgggaggtag taaaaatgat agtagtatta aaaatgggag
    24781 cagataaaaa tgaagttaaa aaattaattg aggctattgg gagagaagga gtagaagtta
    24841 atcccataga tggaacagaa ttaactgttt taggtttagt tggagatact agtaaaatag
    24901 atgccaaaag aatagaagca aataaggtag ttgaaaaagt tatgcatgtg gtagagcctt
    24961 ttaaaaaggc caatagaaaa tttcatccag aaccttcaat cataaatgtt aatggaatgg
    25021 aaattggttc aaagaaaatt gctatgatag ctgggccttg ttctgttgaa acagaagacc
    25081 aaatagtatc tatagctaaa gatgtgaaaa aatcaggtgc aggatttttg agaggtggag
    25141 cattcaaacc aagaacatca ccatacgctt tccaaggatt gaaatatgat ggattggatt
    25201 tattaaaaaa agcaaaagaa aaaacagggc ttcctatagt tacagaaata atgtcaacac
    25261 aagatataga tatatttgaa gaaaatgtag atgtaattca agttggagct agaaacatgc
    25321 aaaactttga tttattaaaa gaattaggta aaacaaataa aacaatactt ttaaaaagag
    25381 gattatctgc tacaattgaa gagtggctaa tgtcagcaga gtatataatg gctggaggaa
    25441 atgaaaatgt agttctttgt gaaagaggta taagaacttt tgaaacatat actagaaata
    25501 ctttggattt aagtgcaatt ttagctgtga agaaacttag tcatttacca gttatagttg
    25561 acccaagtca tgcagcaggt aaatcatgga tggttgactc tttatctaag gcagcaattg
    25621 cagttggagc agatggtcta ataatagaag ttcataatga cccagcacat gcactttgtg
    25681 atggaaaaca atcgattaag ccaaatgaat atgatgaatt gataagtgaa ttaaagacta
    25741 tcgcatcagc agttggtaga gaaatataat ctataaaagg atggttaaac gtggaagaaa
    25801 aactattagt aaatttaaaa gaaaatagct acaatatatt tattaaaaaa aatatactaa
    25861 agaatatagg agaagaaata aaaaaaatat attttggaaa taagattttt attgtaactg
    25921 atgaaaatat agcaaaatta tacttggata aagtaaaaaa taatttaagt gaatctggat
    25981 ttgaaattaa atctttaata ttaaaatctg gtgaagaaac aaaatcattt aatactcttc
    26041 ctaaaatata cgatagttta cttgacttta agttaactag aaaagatttg attattactt
    26101 taggaggagg ggtaataggt gatttaggtg gatttgcagc agcaactttt ttaagaggta
    26161 taagttttat tcaaattcca acatctttat tagcacaagt tgatagttct gtaggtggaa
    26221 aagttggagt tgaccttgag agaggcaaaa acttagtggg aagcttttac caaccaaagg
    26281 ctgtgtttat cgacccaaat gtattattat cacttccaga aaaattctat agagatggaa
    26341 tggcagaagt tataaaatat ggatgtataa aagacaaaac ttttttcaat aaacttttaa
    26401 gtttaaaaaa tagagaagaa gtaatgcaac atatagaata cattatacat aaatgttgct
    26461 ttattaaaaa aactgtagtt gaagctgatg aaaaagactt tggagataga atgcttctaa
    26521 actttggcca tacattaggt catgctattg agaaatacta caattttaca ggttataccc
    26581 atggagaagc tgttgccata ggaatgtata agataacttt agaaagtgaa aagataggaa
    26641 ttacaaaaaa aggtacatca gaacttataa aatcaatttt aatgaattat aatttgcctt
    26701 atgagattga attaagagat aataaatcta tagtagatgc tatatctctt gataaaaaaa
    26761 atctaggtga tacattaaaa ataatacttt taaaagatat tggagagagt attatatata
    26821 atactacttc taaatttttt caggaggtaa gataatggga agtctaaaaa tatatccaag
    26881 taaattatct ggagatgtaa aaataccacc atcaaaaagt atggcacata gggcagttat
    26941 ttgttcatct ctaagcaatg gaaaaagtag aatttctaat atagattttt ctgatgatat
    27001 aatagctact ataagagcaa tgacatcatt aggagctatt atagaaaaga aagaagatat
    27061 tttagaaatt tcgggaattt tttctaaaga aggtatttta aatagagaga atcagttgaa
    27121 tcaacctaaa ttgacaatag attgtaatga atcaggctct acattgagat ttttagtacc
    27181 tatatcttta acatttgatg gtgtaaaaag gtttataggt agaggtaatc ttggaaaaag
    27241 accacttgat acctattatg agatatttga cagacagaat ataaaatata gttacaaaga
    27301 aaatcagtta gatttgatta tatcaggtaa gcttaaacca gatgaattta gagtaaaagg
    27361 aaatataagt tctcagttta tcacaggttt actgtttata ttgcctacgc tagaaagtga
    27421 ttcaaagata ataattacta ctgagctaga atctaaagga tatttagatt taactctttc
    27481 aacgataaaa gattttgggg tagaaattat aaacaataac tataaagaat ttattataaa
    27541 aggaaatcaa acgtataaag cgagagatta taaagtagaa ggagattatt ctcaaggagc
    27601 attttattta tcagcagatg ctataggaga agatattagc atattagacc ttaaagaaga
    27661 ttctcttcaa ggggatagtg aagtagttga aattttatct aggatgggaa tggaaatatt
    27721 aagagaaggc aacaaaataa aaggaataac aaatggttta aatggtactt tgatagatgc
    27781 atctcaatgc ccagatataa tacctgtatt atctgtagta gcatccttaa gtatagggag
    27841 gactacaata attaatgctg gtaggcttag aattaaagaa tgtgatagac ttcatgcaat
    27901 aaatgttgag ttaagtaaac ttggagcaaa tatagaggag aaagaggata gtttgataat
    27961 cgaaggagta agcaagttaa atggtggagt agaggtgtgg agtcacaaag accatagaat
    28021 tgctatgaca cttgcaattg cttcttgtag atgtgataaa ccaataatat taaaagattt
    28081 tgagtgtgta tcaaaatctt atccacattt ttttaaagat tttaagatgt taggaggtcg
    28141 aattgatgag tggaatatgg ggaaataatt taaaagtatc aatttttgga gaatctcatg
    28201 gaaatgctat aggtataaat atagatggtc ttccttcggg gattgaactt gaccttgata
    28261 atattgataa agaaatgaag agaagagcac ctggaaaaaa ttctatatct acttcaagaa
    28321 atgaaagtga tataccagaa attctaagtg gatattttaa tggaagaact acaggaacgc
    28381 cattatgtgc aatcataaga aatagtgata ctcgttcaaa agattatgga gagcttaaaa
    28441 atttaatgag accaggacat gcagatttca caggtaatgt gagatattct ggatttaatg
    28501 actatagagg gggaggtcat ttttcaggta ggataacagc tccattagta ttttgtgggg
    28561 ctatatgtaa acaaatttta tcacaaaaag gaatagagat aggagcacac ataaaaaaaa
    28621 ttaaaaatat agaagatatg agttttgatt atgtaaatat ttcaaaacaa cagttatcaa
    28681 atttgcaaac tttggaacta cctttacttg atttatcaaa ggaagaagcc atgaaaaata
    28741 cgattataga tgcaaaaaat caaggagatt cagttggtgg tataattgag tgtgcagtag
    28801 taggtattaa tgtagggctt ggaaatccat tttttgactc tgttgaatct actttatcac
    28861 atttattgtt ttctgttcct gctgtaaaag gtgtagagtt tggtttaggt tttgaacttg
    28921 cagatatgta tgggtctcaa agtaatgatg aaatgtatta tgaaggaaat caagttaaga
    28981 gcaaaacaaa taacaatgga ggaattatag gagggattac tactggaatg ccaataattt
    29041 tcaaagtggc aattaagcca actccatcaa ttagcagaca acaaaacaca gttaatataa
    29101 aagataaaaa ggacgatatt ttatatatta aaggtagaca tgacccttgt atagttcaaa
    29161 gggctatacc tgtaatagaa gcagtaacag ccattggaat ttttgatttg atgaaaggac
    29221 gataataatg gaggatttaa cgagatatag aaatgagatt gacaatatag ataaagagct
    29281 tattcaatta tttgaaaaga gaatgaatac agttcttgaa attgccagac ataaaatgaa
    29341 aaataacact actatacttc aaaaagatag agaagaaaaa gtactaagta gagctgtaga
    29401 taatttagat aataaagcat attcacaaga aacggtacag ttttttaatt ctataatgga
    29461 aattagtaga ggattacaaa aaagattgat agataatgat ggtgagcaga aaatcgagtt
    29521 tagtttagat tcatcaaata agaaatttga tttgtcaaat gtaaatagat ataagtcttt
    29581 aaaagatgaa ttaaataaaa aaaatatcct agtaggattt ccaggaaaat caggttcatt
    29641 tacagaagaa gcactaaata aattcttcaa caaaaaaata tcaaaaaaac aatttaaaga
    29701 atttgaagat gttttcatag cacttaaaaa taaagaaata aactatggaa taatccccat
    29761 agaaaattca tctacaggag ctatctctga aacttatgac cttttgagaa agtacggttt
    29821 ttatatagtt ggagaagaat gtataaaaat agaccaaaat ttaataggga taaaagacac
    29881 aaagcttgaa gatataaaag aaatatattc tcatccacaa ggtataggac aatgtagtaa
    29941 atttttaaaa caaaatagta catggaaatt gataccattt aataacacag caacaagtgc
    30001 agaacttgta agaaaacttc aagataaaac aaaagcagca attgcaagca aaaaagctgc
    30061 aagtatttat ggattagaaa taataagtcc ttgtataaat gatattgcaa acaactatac
    30121 aagatttgta gtaatcagta atcaaataca cattgaagaa gaatcaaaca aaatgagtgt
    30181 agtattttct gttgaacatg aagcaggaaa actttataaa gtacttggat actttgctaa
    30241 aaataatata aatatgacaa aaatagaatc aagacctatg aaaaatgcct catggagata
    30301 tttcttttat atagattttg agtgttctat atacaatgct aaagtgtacg atttattaga
    30361 attgatagaa cataatacag catattttaa atttatggga gtatataaaa ataaaactga
    30421 atagataaga taaattttta tttaatttat aattattagg aggtgtaagt atgaattttt
    30481 tcggtctagt aggtgaaaaa ctctctcaca gtgtttcacc tcaaatccac aagagagtat
    30541 tcgagatatt gaatattgaa agtgcttata aaaactttga aatttcaaaa gaagatatat
    30601 ctaagctaga cggtgctata aaattattag gaatacaagg ggtaaatgtt actgtaccat
    30661 ataaggagcg tattatgaaa tatcttgatt ttatatcacc agaggcaaaa cgtataggag
    30721 cagttaatac aattttactt agagaaaata tgttatatgg ttacaataca gattactttg
    30781 gtcttgatag tatgtttaaa atggctaata ttgatgttca aggaaaagta gcagttatat
    30841 taggaactgg aggtgcttct aaagctgctc ttacatattt tattgattct ggtatagaaa
    30901 agctttatgt ttcaactaga aaaaaggatg ataaaaaatt attaaatagt aaagctatat
    30961 taatagatta tgaagaactt aaacatataa aaggagatat aatattaaat gctacaccag
    31021 taggtatgta ccctaatgta ggaatttcac cagtgtcaaa atctattata caaaattttg
    31081 atatattaat agatttaatt tacaatcctg gagaaacaga gtttttaaga attggtaata
    31141 gtatgggtaa aaaaacttgt gatggattat atatgctggt ggggcaagca ataaaatctc
    31201 aggaaatttg gcaagatact aaaatagata atagtatttt agatgttata tataatgaac
    31261 taaaattaga atttttgtaa gggagattgt tatgataaat aaaacaaaag aaaaattgat
    31321 attaataggt atgccaggta gtggaaaaac tacaattggt aaacttttgg ccaaagaata
    31381 taattgtagt ttctgtgata tggatgatta tataattcaa atatctcaaa aaagtatagc
    31441 agagttgttt tcagaaggag aagatatctt taggaactat gagactcaag catgtagaga
    31501 actttctata agtgataaaa cagtgatatc tacaggtgga ggtgtaataa aaaaggatgt
    31561 taatatggaa atactaaaag aaacaggtat aataattttt attgatagac ctatacaaaa
    31621 gattttggaa gatataaata ttaattcaag accattatta aaaaatggaa aagatagatt
    31681 gtataatctt tataatgaga gaataaatct ttataaaaaa ttttcagata tagagatttt
    31741 aaatgataaa tcattaaata atgctgtata taatattaca aatgcagtca gtgaaaattt
    31801 taaatttgac tttaaagaaa aataatctag ggggaaataa aaataatgaa tattgttatt
    31861 gtaggactag gagttatagg aggctctttt gctaaagcat taaaaaaagc tggatatgaa
    31921 aatgtatttg gagtagatgt agatttagaa actttaaaaa aagcagaaaa agcaaaaatc
    31981 ataaaaaaag gatgtactac aggtaaagag ttatttaaaa aagctgattt aattatatta
    32041 tctatatatc ctagattagt tgtagatttt ctaaataata ataaaaactt ttttaaaaaa
    32101 gggactataa ttactgatac tacaggaata aaagaaacac ttatcaatga tgtgttgcaa
    32161 attattccag atgatataga ttttatattt ggacatccaa tggcaggtag ggaaaaaaag
    32221 ggtattgatt ttgcaagtga acaagttttt aatggcgcaa attatataat tactccaact
    32281 ggcagaaaca acataaaaaa tttagagtta gttgaaaatt taattttaga gattggattt
    32341 aaaagagtaa aaaagttaac ttcacaaaaa catgatgaga ttatagcttt tacttctcag
    32401 ttacctcatg ttatggcagt tgctcttata aatagtgatg aagaaggtag agatacgggt
    32461 aaatttattg gagatagtta tagagattta actagaattg caaatatgaa tgaagactta
    32521 tggagtgaac tttttttagg aaatagagat aatttactaa aagttataga aaactttgaa
    32581 tcagaagtaa atttagtaaa agaagctata tttaacaatg ataaaaataa attaatagag
    32641 tattttaaaa aatcatcaat aagaagagaa gctttagaaa aataaatatt aatatttaag
    32701 ctatatatag atgggtataa atataagcga tagtgtattt aattgtatta ataaatatgg
    32761 attcaatata attaaatatg ctattgatat atttgtaccc ttaactattg ttatctttta
    32821 aatgataatg atatttattt aaatactctt tattaacaat ttataaaact taattgtaaa
    32881 aaatacttat taatagtaaa ataaagtgaa tcaattatat tataattgct aaagagagtg
    32941 aggtgtagct atttgaaaaa aaatagatta atagcaaaga atatatcaat agcatttata
    33001 gtactattct tttttagtgt atttacattt ttttatgtag gtaatattaa tagagtgtta
    33061 gaatatgaaa caaatgacat aataacagtt acaattgctg gatggattat actttcattt
    33121 ttatttttag gtattataat ttacatatta tattcaaaag caaatagtca aaaaactata
    33181 gaaaaagtag catatacgga ttttgtaaca ggttattcca actggagaaa gtttgaatta
    33241 gatgttacaa atttattaaa gaaaacatca caaaataata aatatgcaat ggtcatattc
    33301 gatattgata aatttaaagc aattaatgat atatatggcc ataaaaaggg aaatttaata
    33361 ttaaaagata ttgcagatac tttaaatgaa ttgactgata tcaatgaaac ttttgctcgt
    33421 gtaagtgctg ataatttcaa tatattatta acatataaca aaaaagagga tataataaat
    33481 attatcaaaa agattatggc aaataatgaa cttgtaaact tatcttttgg aatttatgaa
    33541 atcaaagata aggatttatc tgtaagtgta tatagtgata gagcttcact tgcaaaatca
    33601 tcaataaaaa ataatagtga tgtaaatttt gcatttttta atgacaaatt aagagagaaa
    33661 ttattatttg aagataagat agaaaaagaa atggaatatg ctcttgaaag tgggcaattc
    33721 gtaatgtatt tacaaccaaa atacaatatt aaattagata aattttgtgg aagtgaagcc
    33781 ctagtcagat ggcaatatac agaaaaagag gtcatatatc caggtgattt tattcctata
    33841 tttgaaaaaa atggatttat tagaaagatt gatatgtaca tattagaaca agcttgtaaa
    33901 gaaatccggt ctttatttga taaaggaatt tcacctttac ctatatctgt aaacttctca
    33961 agagttgatt tttttaaaaa agattttatt gaaaacatag taaatatatg tgatagatat
    34021 aaaataccat atagtttaat agaaattgaa attactgaat ctagtatgtt tggagatact
    34081 gatactctat ttaatgttag tagaaaccta caggatattg gctttatagt tgcaatggat
    34141 gattttggct ctggatattc ttctgtaaat atgcttaaaa atataccatt aaatgtaata
    34201 aaattagata gaggattttt tgttgatgat aaagatgttg ataagagtca aattgttata
    34261 aaaagcatag tttctctcat taagcaatta ggaataaggg ttgttgctga aggaattgaa
    34321 acaagaagtc aaatagaaat gttaaaaaaa gcaaattgtg atattgttca aggatattat
    34381 ttttcaaaac cattaccaat taaagaattt gaaaaattag tctataaaat atagtcagcg
    34441 agtcttaaat gggaggtggt gattaagtga taagagcaaa atcgttaaaa aatgtactga
    34501 gtattgtttt aatattttta tttacaataa tttctttttc tgattttgca tttaaaacta
    34561 atgtccagga agaagaaaat agtaaaatta atttaagaga aatatcccta caaagttcca
    34621 atgctataaa aataaaatta gatagttctc tatcctttat taaaagtgtg gcaaatatgg
    34681 tttcttattt taatactata gataactcaa aaatagttcc attattagct aatatatcaa
    34741 aagaatctga ctttcaaaga atctctattg tatctcctga tggaataagt cataccagtg
    34801 atggcaaaat tatcaatgtg tcaaagtatc agtattttaa gaaagctatt aaaggagaaa
    34861 gtaatatatc tgaagttgtg aaatctccaa ttgatggaaa agatactttt gttatagcta
    34921 ctcctgtatt taataagaat aacaaaataa ttggtgtttt atacggttct tactacaatg
    34981 ataaattagc tgaatttata gatataacaa gttttaatag tgaagggtac atagatatat
    35041 ttgaatctag tggtcaattt gttttaaaat cttcacatac aaacaaactg attaagtcaa
    35101 gtagtaacat atatgatata tttaaaaaag cttcttttga tgatggttat agctataaaa
    35161 aaatatatga agatacaaaa aataacaaga gtggctttac ctcatatgaa tacaaaggag
    35221 aaaatcgtta tgctacttat acacccattg gtgtaaatga ctggtatgta atttctgtga
    35281 taccacaata tactgtaaga agaaacattg ataaaataaa tcaattagca ttttctctta
    35341 ttttcaaggt attcttattg tttattatgc ttataatata tattatttat aaaaacaata
    35401 aatctcagaa agatatacta aaagctaaca aagaaatctc atctattaca aatagcattc
    35461 ctggaggagt acaaaagtgt accctgggtg aaacatgcaa tattaatttt ttaagtgatg
    35521 gatttataga gttgtttggt tatacaagag aagaaataaa aacattgttt aataatgatt
    35581 tttatagttt aatacataaa gatgatgttg aaagaataaa aaaagaaatt tttaaacaac
    35641 tttacaaaaa taaaactgtt gaattagaat ataggattat aacaaaaaat ggtaatacag
    35701 tatgggtttt agataaaggg gagcttataa cagaacctga tggaaaagaa tatttttgtt
    35761 gtgtaactgt agatattact agaacaaaac aattagaaca agagatggaa caaaaaaatc
    35821 tagaacttga aatgatatca gaaaatgttt taggtggtat aattataaca gaatttaatg
    35881 atgattttac tataaaatac gctaactctg gttatctttc aatgattgga tatacacgtg
    35941 aacaattaga aaatgaactt aaatacaaag cttgtaatct tgttttttat gaggataaaa
    36001 agaaggctct tgaaagtata caacatcaat taaacacaaa aggaatagct gtatatcaac
    36061 atagaataag aagaagaaat ggtaatatta tttgggtttc tataaaagga aggcttattg
    36121 ttgatgatgg tattgaaaaa ggtatttgga ttctaaatga tataacagat ttaaaaaatg
    36181 cagaacaaaa acttaaaata aatgaagaaa gatttagaat tgcattaaag caaacatcaa
    36241 acactatatt tgagtatgat ataaaaacaa agtcactttt aaatactagt aaagagcttg
    36301 ataaatataa tatttataaa attactaaaa acgttccata ttctctagta gaatcaggag
    36361 ttattcataa agattttagt gatgatttta taaacatgta tgaaaatgta ataaatggag
    36421 caaaaaaagc aagttgtgta gttaagatga aacttccaga tgaaaattat atatggaata
    36481 aagttacctt gactactatt tttgatgaag atggtaatcc tgtaagagca attggtatac
    36541 aggaagatat aagcaaacaa aaggaagcag agataagata caatcaagaa ggtaagtatc
    36601 attcagctat attgtcggaa gcaatgataa cttatgaaat aaatgtatca aaggatactt
    36661 ttatcaaagg aaatgaaagt tggcaaaaac catttggaat taagcctgac aataactatt
    36721 ctcaaatggt aaaaactata gcaaatagta ttgtacataa agacaataaa gaaacatttt
    36781 taaatacatt tttatgtgaa aacttattgg atgcatataa aaataatgtg actgaaataa
    36841 aattagaata tcgaagaatg aatcaagaaa ataaaatgat ttgggtcatt tgtacaatgc
    36901 acttaataaa agattctatt acgaacgata taaaagcact tgcttatgtt aaagatattg
    36961 acaagcaaaa aaatgaagaa attagattaa aattaaaagc tgaaagagat actcttacag
    37021 gattatataa taaaggtact acagaaaaat tgattaatga tttcttgaac tctgaggaag
    37081 caagcttagg aatgcatgca tttttaattg ttgatataga taattttaaa tctgtgaatg
    37141 ataatttagg acatgtattt ggagataaag tattatttga agtttctaaa aacctaaaac
    37201 ctatatttag aaaagatgat atagtaggta gaattggtgg agatgaattt atagtattct
    37261 taaaaaatat tcagtctttt gagaatatca aaaagaaagc agaaaaaata tgcgatatat
    37321 ttagaaattc ttatacagaa aataaaaaga catataaaat atctggaaca gttggaattt
    37381 catttgtacc agaacatgga actgtatttg aagaacttta taaaaaagca gacatagcac
    37441 tttattatgc aaagagcaaa ggaaaagata agtatgcact ttataatgat tgtatctacc
    37501 aaaatgaact tgaaaataat ataagtgata ataatataaa attagcagat aaatgtgaga
    37561 aatccaaacc agtacttaaa gaaattcttg attctattga taattatatc tatatagtga
    37621 atccaaatac ttatgaactt ctttttgtca ataataaggt gtctcgtttg gatttagaga
    37681 taaaattagg agaaacctgt tataaatcac tattaaaatc tgatagacca tgtaataatt
    37741 gccctcttaa cggattagaa gaaaataagc attcaaaatt caaaatagag acaaatacat
    37801 ttggtaaaaa tatcagtata gcaagttgga ttaattgcat agatggagaa tacaactgtc
    37861 ttatagagtg tatagattct tctttataca aaaataaata aaaaaggact atgaagatat
    37921 gttaaatagt ataactttga tacttggtat aatatttaca atttactatt tttatctcaa
    37981 aatagttttt ggaggaattt catttagtga gattttctta gttgtaggaa ttgtactaat
    38041 tatctatcaa atatttaaga aaaaaattaa agaaaagaag gttttttata gggtgttaaa
    38101 aataataatc agcatttttt taatagtatt tgtagttact gagagtctaa ttatttttta
    38161 tcccaaaaat agtttagaat caaaaagtga ttatctctta attttaggag cttctgtaaa
    38221 aaagactaca ccaagtacaa ccctgaaggg taggttagac actgcattga aatacctaaa
    38281 aattaatgat aattgttatg tggtagtatc tggtggtaaa ggaagtggag aaaaaataac
    38341 tgaggcaaaa gctatgaaag attatcttat aaaaaatggt atagataaaa ataggataat
    38401 agaagaggat aaatccacga atacttatga gaattttaaa tattcaaaat tgaagataga
    38461 agaacatagt caaggaaaac taagcgattt aaaagtaaaa atagtaacaa cagattttca
    38521 tgttctcaga agtaaaatat tagcatatag aaatggatat aaaaatacgt ctttttatgc
    38581 tagtaaatca aaactttcat ttgtaccaac ttactataca agagaatttt ttgcattatg
    38641 gaaaacaatc atttttgata gataataaat aaaaagacta gatataaact catatctagt
    38701 cttttctatt cccttaattc taatccattt tccaacttta cttgttgtag aaatttcaac
    38761 attgggattt acaagtaatt gcttataaga agttttatat tttacgattc caaaatataa
    38821 ttttccttca taatccatta taaatccgaa tggtcttact cttggtttat tatcttcaac
    38881 tgtagcaaaa tagaatgttg agttttcttt aaaaaaattc attatttttt catgattaaa
    38941 tcctctttgt atcttatact aatata
//
LOCUS       DAYAOO010000033        38791 bp    DNA     linear   BCT 12-OCT-2024
DEFINITION  TPA_asm: Clostridioides difficile isolate ST8-SSI-h139-18
            SAMN40601845-rid21577343.denovo.033, whole genome shotgun sequence.
ACCESSION   DAYAOO010000033 DAYAOO010000000
VERSION     DAYAOO010000033.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN40601845
            Sequence Read Archive: SRR28438827
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 38791)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 38791)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-MAY-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-MAY-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002157583.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002157583.1
            Genome Coverage       :: 163x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/11/2024 16:19:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 4,038
            CDSs (total)                      :: 3,963
            Genes (coding)                    :: 3,930
            CDSs (with protein)               :: 3,930
            Genes (RNA)                       :: 75
            rRNAs                             :: 6, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 60
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 33
            CDSs (without protein)            :: 33
            Pseudo Genes (ambiguous residues) :: 0 of 33
            Pseudo Genes (frameshifted)       :: 7 of 33
            Pseudo Genes (incomplete)         :: 25 of 33
            Pseudo Genes (internal stop)      :: 11 of 33
            Pseudo Genes (multiple problems)  :: 8 of 33
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..38791
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN40601845-rid21577343.denovo.033"
                     /isolate="ST8-SSI-h139-18"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Denmark"
                     /collection_date="2018"
                     /collected_by="Statens Serum Institute"
     gene            complement(441..2828)
                     /locus_tag="ACGI5H_001873"
     CDS             complement(441..2828)
                     /locus_tag="ACGI5H_001873"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429705.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0042625 - ATPase-coupled ion transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0006812 - monoatomic cation transport
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="heavy metal translocating P-type ATPase"
                     /protein_id="HFG9697576.1"
                     /translation="MEANNSIKKEFILGGLNCAHCAEEINNKVSKLQEVKSSNLNFIN
                     KKLTVNIKESFNEDTTIEKIIDIIDSTEPGLDIQISSKENAASKTSIKKELILGGLNC
                     AHCAEEINNKVSKLKEVESSNLNFVNKKLTVNISNNFEEDDVINKIKEIINSTEPGLD
                     IQVGSTDKVKGRTTEKSGAVNDTNKKELIPLIIGALVYIFGIYQTATGYESQFSNIVF
                     IVAYVIVGGDVLLRAIRNISKGRVFDENFLMALATVGALAIGELSEAVGVMLFYKVGE
                     YLQGVAVGKSRKSITSLMQIRPDYANLKVNSEVKVVSPEEVNVGDIIVVKPGEKVPLD
                     GVVVDGVSMLDTSALTGESVLREVEKGDEILSGVINKNALLSIEVTKSFGESTVSKIL
                     DLVENSSIKKSKTENFISKFSRYYTPIVVIAALLIAFVPPLVISGEVFSDWLYRGLIF
                     LVVSCPCALVLSIPLSFFSGIGFASKNGILIKGSNYLEALRSVDTVVFDKTGTLTKGV
                     FNVTKLNPEGISEEELLEYAAIAEVNSNHPIAKSILSYYNKKIDLDTIDSYEEIAAYG
                     IRVKHNGNFILAGNEKLMKKENISYSSAKEVGTVVYIAVDKAYRGYIVISDEVKEDSK
                     NAIRSLKEIGVKEVVMLTGDNEKVAKNIAQELELDTVYSNLLPNEKVDRLEDLYEGRT
                     EKEKIAFVGDGINDAPVLARADVGIAMGGLGSDAAIEAADVVLMTDEPSKISKAIEIA
                     NKTNKIVWQNIIFALGVKIIVMILGAGGVATMWEAIFADVGVALIAVVNAMRAMR"
     gene            complement(2851..3216)
                     /locus_tag="ACGI5H_001874"
     CDS             complement(2851..3216)
                     /locus_tag="ACGI5H_001874"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437587.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="metalloregulator ArsR/SmtB family transcription
                     factor"
                     /protein_id="HFG9697577.1"
                     /translation="MREEINDCNCNIVHEEIVTEAKSTMPDEEMLYDLAELFKVFGDT
                     TRVKILYALFANEMCVCDIASLLNMTHSAISHQLRVLKQARLVKFRREGKTVYYSLDD
                     SHISQIFDCGLNHIRETYK"
     gene            3415..4263
                     /locus_tag="ACGI5H_001875"
     CDS             3415..4263
                     /locus_tag="ACGI5H_001875"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421082.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9697578.1"
                     /translation="MSNKKKKDLDTSYMPYLDPANYADYITNEEIPQDELRNDPQISN
                     GYTKIPNNQNINNLYPNNVNHYPKSSNSPNNLPNTNNTSGNMNYNTSATNNMPNNMNN
                     NTGMPNNMSNNMNSNMGMPNNMPNNMNSNMGMPNNMPNNMNSNMGIPNNVPNNMNSNM
                     GMPNNMSNNMNSNMGMPNNMSGNMNNNMYGNTGMPNNMNSNMGYNMNNTMGIPNFSCN
                     QNMPPNVLMMIPGVICHNTMQGMPVVMPSTMPPNIYPTPYGSSNMSIQGIPQATNIEE
                     FDEEEM"
     gene            complement(4700..5788)
                     /locus_tag="ACGI5H_001876"
     CDS             complement(4700..5788)
                     /locus_tag="ACGI5H_001876"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425141.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9697579.1"
                     /translation="MNFNFAKATNSRLMGSLGLIINWIDDENNHFCQYFLLDAEGLGL
                     ADYVSLNNPTQEEAYMEEERLMGGFGSDRVELTKDESLFLVSYFGNKNLYYDKLLPGD
                     KCEYIDIIKNYKTDLTIEKLYNKICKRVDEEVEFINYMTMRFIAWDRESLKYFSGSDE
                     IANMHITNINGTLLKNVVSDKGQGRYISEALYEDNDGYYICKIAFCISKCYETGFRIN
                     SLLVTDKEPMYDFEVFDEISKSEFVSVYSVNSPEEFAGVFYRENPFLLKSNMNEGIFF
                     TRFNFNNDHVKENVYIINNDMKAIYYLMGNKFFIGTYNENDCNYINEISQSNYSDYIK
                     FEEKFFFEQNALYDFAESGSLDFDDFLE"
     gene            5913..6641
                     /locus_tag="ACGI5H_001877"
     CDS             5913..6641
                     /locus_tag="ACGI5H_001877"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421079.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family hydrolase"
                     /protein_id="HFG9697580.1"
                     /translation="MKNIAAFFDIDGTLYRDSLMVEHFKKLIKYDIIDQKNWYKHARD
                     TFMDWDKRQGNYDDYLLEICDLYVDSLKGLDKTCINFTSDQVIKLKADRVYKYTRSRI
                     EWHLNQGHIVIFISGSPGFLVEKMAKKYNVTDFLGSDYVFENNIFTGTVIPMWDSISK
                     NNAINDFVVKYDLDLSNSYAYGDTNGDINMLKRVGNPIAINPTKELLSQISLDEEISK
                     NVEIIVERKDIIYSLSTDVNIVDI"
     gene            complement(6843..7334)
                     /locus_tag="ACGI5H_001878"
     CDS             complement(6843..7334)
                     /locus_tag="ACGI5H_001878"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009904849.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9697581.1"
                     /translation="MSIKVAYGGVLLALNVILLTLTNIIPVNTLFIMGLASLLVSIVI
                     MEWGFKSGIAFYIGSIVLGFIVMASKSQWIVYSLTFGIYGIVKYLIEKDRSIYIEYFM
                     KLVFANIMILILYFLLRTIVYIPINIFIIGSFEIAFIVYDYVYSSFIGYYNNRLRKML
                     FKK"
     gene            complement(7345..7788)
                     /locus_tag="ACGI5H_001879"
     CDS             complement(7345..7788)
                     /locus_tag="ACGI5H_001879"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425143.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9697582.1"
                     /translation="MYSNTYNNENFMRARAFIENSEFKKAYDFLKTLTDKCAEWYYLT
                     GFSAMNIGYYEEGEDFLKRAKFMEPENSEYSDALRSYTQYRNDYSNRADNYNRRRRND
                     LDGCCCCCCDDCCCCLGDDCCENCAKLWCLDSCCECFGGDLITCC"
     gene            complement(7778..8617)
                     /locus_tag="ACGI5H_001880"
     CDS             complement(7778..8617)
                     /locus_tag="ACGI5H_001880"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421074.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF5685 family protein"
                     /protein_id="HFG9697583.1"
                     /translation="MFGYVKINKMDLTFREYDYYKAYYCGLCKYLKRNHGEISRFSLN
                     YDITFLIVLLTAVYNPESISTEEVCIVNPFKKKKVITNDITEYAASMNILLTYYKLED
                     NLMDDKRIKDKLAYYIYKNKLKLAYEKYPEKAEYIKQQLNELNKLEKDKNINIDEVSS
                     IFGNIMGEVFVYKKDENERNLRMIGFNIGKYIYLLDAYEDLDEDFKKGRYNPFIEYID
                     KNDELKEKVKKIIVTSLGFLARGIDNLNLNKNVGIIENIIYSGVYLRYINILESRGGK
                     NVQ"
     gene            complement(8836..10221)
                     /locus_tag="ACGI5H_001881"
     CDS             complement(8836..10221)
                     /locus_tag="ACGI5H_001881"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860725.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M20 family metallopeptidase"
                     /protein_id="HFG9697584.1"
                     /translation="MENLNKKFLMEYIDEIQGELRDISDKIWKNPELQYKEYYASNLQ
                     KEYLKKYGFSIDELEGMDTAFAASYGEGRPVIAVLGEYDALDSLSQKVSTIKEPIVDG
                     GAGHGCGHNLLGTGSIGAVIAVKELIKLKKLKGTIKYYGCPAEEDLSGKVLMIKKGFF
                     DGIDCAFSWHPFDINTPIRIPTLANYSVKFRYNGISAHAAQAPYNGRSALDAVELMNI
                     GCNYLREHIFDNCRVHYVTTNGGKMPNIVPDFAEVWYYIRGVKMEHVRDVFGRIVDIA
                     KGAALMTGTIMEYDIISGVYDYIPNTILTDILSQNMKLVGVQNYNEDDYYFADKLAET
                     VSIDKRSSVSSVLSGNKDITKMNLHDEVTDDTFTHNNCISLSLDIGDVSYIIPTAQCS
                     CSVWPIGISAHTWQSCASAGSDMGFKAMLLASKSISCSINDVMLDELVINKAKKELKD
                     TVGSFKYIPII"
     gene            complement(10394..11137)
                     /locus_tag="ACGI5H_001882"
     CDS             complement(10394..11137)
                     /locus_tag="ACGI5H_001882"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435911.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine amidotransferase"
                     /protein_id="HFG9697585.1"
                     /translation="MKKVLIVGESWVKNITHIKGFDTFVTTHYEEAVKWLKEAIESGG
                     YETVHMPAHVAADSFPYKLEELNEYDCIILSDIGSNTFLLSNSTFIDCNSNPDRLELI
                     KEYVNNGGALIMVGGYMSFTGIDAKARFGETAIKDVLPITMIDKDDRVEKPAGIIPEV
                     IDSKHPVLKGIPTEWPKFLGYNKTVARDNCPVLATIGGDPFVAVGEFGKGKSAIFSSD
                     CAPHWGPKEFTDWKYYNKLWVNMLDWLTC"
     gene            complement(11157..12419)
                     /locus_tag="ACGI5H_001883"
     CDS             complement(11157..12419)
                     /locus_tag="ACGI5H_001883"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729135.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M20 family metallopeptidase"
                     /protein_id="HFG9697586.1"
                     /translation="MKKILLDTLNSKKQEYIDYLKELVSIKTEDVGHGILGGFEKEGQ
                     EYIEKLANYIGFSVDRQEMSEELIKKAKNIYKEGNLGHNYQDRYNLICKYSDDLPGKT
                     IVFNGHVDTMPPGDISKWKYNPYRATEDNGKLYGLGTADMKSGLIASILAVKLIKDSG
                     LNVPGNVKIMSVVDEEGGGNGTINAVMNGIDGDCCIICEPSEQNLIVAHMGFVFFEVE
                     VKGVSLHCGSKWEGVNAIEKAMLLLQDIKELEHNWLMIYKHPLLPSPTINLGVINGGT
                     AGSTVPDKCVFNLCVHFLPNIMSYEQVVNDVTNVIMTRANGDLWLKDNKPNINIYQSG
                     LGFEMDKDSDFVVNAHKILEETLGKKLEIKGSTAGNDARLMKNLAEIPTLILGPGSIE
                     QCHSIDEYVEIKEYLDSILMYASLILNL"
     gene            complement(12603..13601)
                     /locus_tag="ACGI5H_001884"
     CDS             complement(12603..13601)
                     /locus_tag="ACGI5H_001884"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421067.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HFG9697587.1"
                     /translation="MSSITKHKEEKSSPLLTKLTSVFRDQGSAAVGLVIIFIIMSVAS
                     SNFLTLDNLINVGRQISINAILAVGMTFVIITGGIDLSVGAVIALVGTFWATTVVNYN
                     APIWVGMILALAIGTILGVIKGAIISTQKLPPFIVTLAMLTIISGASFVFTGGRPISV
                     NTDAFKMLGRGYIGPIPIPVIIMIIVVIAGHFLLKRTNFGRHVHAVGGNEEAARLCGV
                     KVNKVIVKVYALAGLLTALAGIILSSRLASGSPTVGDGAELDAIAAVVLGGTNMMGGS
                     GSIVGTCIGVGIIGILGNGLNLLSVSSYNQMIIKGLVMLFAIWINNIKLKKSAKSK"
     gene            complement(13585..15096)
                     /locus_tag="ACGI5H_001885"
     CDS             complement(13585..15096)
                     /locus_tag="ACGI5H_001885"
                     /EC_number="7.5.2.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860721.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter ATP-binding protein"
                     /protein_id="HFG9697588.1"
                     /translation="MSNIILKLSNIAKEFPGVRALDNVNFELFHGEVHALLGENGAGK
                     STMIKILTGAHSKTSGKFIFEGKEIENISPDISKKIGINAIYQELTVFDELTVAQNIF
                     MGKEINGKVLTNDKKMNEEAKKIFDNMGIDINPNSLVKELSIAQKQMVEIARVLSSET
                     KVLIMDEPTSSISKKETEILFRLINDLKESGVSIIYISHRMEELFEICDRITIMRDGK
                     TISTLNTKDVSSEEELVNLMIDRKLDQFFPKRKVEIKEEIMRVENLTKNNVFNDISFN
                     IRKGEILGIGGLVGSKRSEIVEAIFGLRTYDSGKIYLNNEEVKFKTPSDAIENGLGLI
                     TEDRKGTGLFLQMSVKENTTMAGLKKISKFKSIIDRKKEKEILEKYIEALKIKTPHMN
                     QVIQSLSGGNQQKAIIARWLLLQPDILIMDEPTRGIDVNAKAEIYNLMGDLVESGVSI
                     IMISSEIPELISMSDRIMVMREGHISGFLEGEEMVENNVLKLAFGGKINEFNN"
     gene            complement(15150..16112)
                     /locus_tag="ACGI5H_001886"
     CDS             complement(15150..16112)
                     /locus_tag="ACGI5H_001886"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435917.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="substrate-binding domain-containing protein"
                     /protein_id="HFG9697589.1"
                     /translation="MRVRKILSLGIAGILAIGMLTGCSMEGPSKSDNKGGSDKKDLTI
                     GVSTITLQHQFFIDIDEGIKEKAKELGVKVIVNDPDQDVAKQTSAIEDFIQQNVDGMI
                     VLGTDNSAIVPAVEGAFEKMPVVTVDAVLNTENITSYVGTVSYDAGKKLGEYTKKYID
                     EKLGGKSEIAIVTDLKSQIQMQRIDGFKDALKGSANVKILNSQPGYDREESLNTVENL
                     IQSNPDVDIIYATAENSVLGAKAALESAKNKDVKIVGFDLTEEASSGITDGTILAMIQ
                     QQPKEMGRLAVEAVVKAIKGEKVEKNIPVPALLYDKENIKDFKN"
     gene            complement(16160..17050)
                     /gene="rbsK"
                     /locus_tag="ACGI5H_001887"
     CDS             complement(16160..17050)
                     /gene="rbsK"
                     /locus_tag="ACGI5H_001887"
                     /EC_number="2.7.1.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895372.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004747 - ribokinase activity [Evidence
                     IEA];
                     GO_process: GO:0006014 - D-ribose metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribokinase"
                     /protein_id="HFG9697590.1"
                     /translation="MGNIVVIGSVNMDMVCSVDKRPEKGETVLGNSFFTSPGGKGANQ
                     AISASKLGANVKMISCIGEDGLGEELIRNFRTNKVDYSLVSRNNHKSSGVAVITLCEN
                     DNSIVVVPGTNELVDIELIKKNEEEIKNADIVLLQLEIPLKTINYVVNFCFENRIRVL
                     LNPAPAVKLNEDIIEKVTYLTPNEHEYKIVFDTNEGIEEVLKKYPNKLVITEGKNGAR
                     FYDGEEIKHVSCISVDVQDTTGAGDTFNGALAVAITEGKNLYTAVEYAVVVSGLSVTK
                     LGAQSGMPYKEDVEKYLNNK"
     gene            complement(17092..18114)
                     /locus_tag="ACGI5H_001888"
     CDS             complement(17092..18114)
                     /locus_tag="ACGI5H_001888"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435922.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HFG9697591.1"
                     /translation="MNFLSITIKEIGELAGVSKTTVSKVINNKDENISQATREKILKI
                     MKEKNYVPNKLAQSLVTKKTNTIGLLIPDIRNPFFTDVSRGVEDKANEEGYNIILCNT
                     DEDAKKEYEGIRTLSERMIDGIIFAASSNTNWKEANYKDIKIPTVLIDKKISMNKETL
                     KGIVKINNFEGAYIATKHLLDIGNKKIIYLSGPLQNEIAVDRLEGYKKALIECNLSYN
                     PAYVFEGKYKIEWGQEFIKNLEKIDFDAIFCANDLIAIGVIRGLKERGLSIPNDISVV
                     GFDDIQTSSLISPSLTTVKQPSYDIGYKASEILINCLRGDKKESFDELIFKPELVIRD
                     STKESE"
     gene            complement(18334..19311)
                     /gene="bioB"
                     /locus_tag="ACGI5H_001889"
     CDS             complement(18334..19311)
                     /gene="bioB"
                     /locus_tag="ACGI5H_001889"
                     /EC_number="2.8.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895370.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004076 - biotin synthase activity
                     [Evidence IEA];
                     GO_function: GO:0051536 - iron-sulfur cluster binding
                     [Evidence IEA];
                     GO_function: GO:1904047 - S-adenosyl-L-methionine binding
                     [Evidence IEA];
                     GO_process: GO:0009102 - biotin biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="biotin synthase BioB"
                     /protein_id="HFG9697592.1"
                     /translation="MEKYIIKLKNKVLREKEISYEEALNLISLDTNNKNDFDILLKSA
                     NEIREYFMGRKADLCTIMNAKSGKCSEDCKFCAQSSHYKTGVEEYSLLDYNEILNRAK
                     EMESKGVHRFSLVTSGKGMSGKEFNNILNIYEGLRENTNLKLCASLGIIDYEQAKMLK
                     SAGVTTYHHNVETCRDNFHNICTTHTYKDRIKTIKDAKKAGLDVCVGGIIGMNESEEQ
                     RLKMAFEIRELNVKSFPINILNPIKNTPMENYDVLEPMEILKTTAVFRFIIPNVYIRY
                     AGGRLSLKGYDKVGFNGGVNSAIVGDYLTTVGSGIENDKKMIIEQGFEL"
     gene            complement(19517..19780)
                     /locus_tag="ACGI5H_001890"
     CDS             complement(19517..19780)
                     /locus_tag="ACGI5H_001890"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729134.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9697593.1"
                     /translation="MKIYYEKENSKKANVNNIPSVFAFNFLRNFLTSKEYEETRKEYF
                     INNLTKSQVNQAMKDLKWLFREYEGLEVITMESLDGVKTRIVL"
     gene            complement(19850..20923)
                     /locus_tag="ACGI5H_001891"
     CDS             complement(19850..20923)
                     /locus_tag="ACGI5H_001891"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421053.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF362 domain-containing protein"
                     /protein_id="HFG9697594.1"
                     /translation="MEKSKVYFCDLYSNSQNKNVPNNVRRLFDEAGFKDLIEKNDQVA
                     IKLHFGEKGNTTYMSPVAVRQVVDKVKDCEGKPFLTDTNTLYTGSRTNSVDHLTTAIE
                     NGFAYAVVNAPVIIADGLYSRNYENVKIDKKHFESVKIGGEIYNSSAMIVMSHFKGHE
                     AAGFGGALKNLAMGCASAAGKQMQHSDVTPVVKEKKCVGCGKCVNSCPTKAISIVDKK
                     AVIDSDVCYGCGECPTVCPTRAVTIQWESDSDVFVEKMAEYAYGAVSNKKDKVGYITF
                     VMNVTPLCDCVPWSGRPIAHDIGILASTDPVAIEQACYDLICKEMGHDVFKHEHPHVN
                     GTRIIDYACEMGMGSKEYELIKL"
     gene            complement(21171..21929)
                     /locus_tag="ACGI5H_001892"
     CDS             complement(21171..21929)
                     /locus_tag="ACGI5H_001892"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421051.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease subunit"
                     /protein_id="HFG9697595.1"
                     /translation="MREYIAFTKKEFKENLRNYKLFSLIILFLIFGISSPISAKFMPD
                     LIAHFAPTLKVTAAPTALDSWTQFFSNISGLGMSLTLIIFCNILSNEYSKGTLVIMLT
                     KGLSRSSIVLSKFSVTVIIMTIGFWLSFLFAYGYTIYFWPTANLNHIIFSAFNLWLIG
                     IMYISVLILGCVLFRPAFASVLLVLVATLLLSLISIPKQIAPYTPNFLMSKNIDLISG
                     KVAMPEFIIPIIITVLISVVCLLAAVILFNKKPV"
     gene            complement(21926..22846)
                     /locus_tag="ACGI5H_001893"
     CDS             complement(21926..22846)
                     /locus_tag="ACGI5H_001893"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018112707.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HFG9697596.1"
                     /translation="MMNIVSINGLSKGFGNRKIIDNLNFTVPEGSVFGFVGKNGAGKT
                     TTMKMVLGLLKPDSGTIDVCGEKVTYGKTSSNRHVGYLPDVPEFYNYMRPLEYLSLCG
                     EITGLSKKEIQIRSEELLSLVGLGNEKRRIGGFSRGMKQRLGIAQALLSRPKLLICDE
                     PTSALDPVGRKEILDIMLKIKDSTTVIFSTHILSDVERICDHVAILNKGSIALSGTLS
                     EIKSMHGKDRLLLEFASNDEIQKFKSSDGIKSLLKDSEETNMEIVLHGKDIKAIQKTV
                     ISTLAEMNLCPVKMELIELSLENLFLEVVK"
     gene            complement(22843..23043)
                     /locus_tag="ACGI5H_001894"
     CDS             complement(22843..23043)
                     /locus_tag="ACGI5H_001894"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421047.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PLD nuclease N-terminal domain-containing
                     protein"
                     /protein_id="HFG9697597.1"
                     /translation="MENLMEYLPLLVPVIILDLILIITALVHVLRHPNYKIGNKAIWI
                     IVVLFISLIGPILYFTIGRGEE"
     gene            complement(23048..24142)
                     /locus_tag="ACGI5H_001895"
     CDS             complement(23048..24142)
                     /locus_tag="ACGI5H_001895"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425158.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HFG9697598.1"
                     /translation="MNELNIAKTLILKRKEKGITQDELANYIGVSKASVSKWETGQSY
                     PDITFLPQLATYFNITVDELICYEPQMMKEDINKLYNKLCKDFTVKPFDEVMDEIREI
                     IKKYYSCFPLIFRMGLLIVNHYDIVDEKKRELLISEALEIFIRIQETCNDIDICRQAK
                     SMEATCYILLNQPIQVIDLLQNSNFPMINESILLAQGQMMNGQMDEARETFQLGAYQN
                     LISLVQNLVGILQNADKLQMKEIERRILAISDIFELDTLSPAIMLSSYLTQAQINLIH
                     GDNEGAIKSLRKYVDLATRDIYPIIIHGDDFFNKLDRWISEIGTGITRDDTIVKAGIV
                     AAIKNNPMFSVLSENKEYKFLIEKLSLLEE"
     gene            complement(24652..24792)
                     /locus_tag="ACGI5H_001896"
     CDS             complement(24652..24792)
                     /locus_tag="ACGI5H_001896"
                     /inference="COORDINATES: protein motif:HMM:NF021468.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2185 domain-containing protein"
                     /protein_id="HFG9697599.1"
                     /translation="MNGEGCILSNKITKECYKVGYMIREKSIDTYPDSGWGFMTWDEN
                     GE"
     gene            complement(25102..26409)
                     /locus_tag="ACGI5H_001897"
     CDS             complement(25102..26409)
                     /locus_tag="ACGI5H_001897"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729132.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M20 family metallopeptidase"
                     /protein_id="HFG9697600.1"
                     /translation="MDISRSVDNSLNRTIEFLKELIKIDSQQGEPISQCPFGIGPKKS
                     LDKTLDYCASLGFSVKNIDNYIGYAEIGEGEELIGIPMHLDIVPPGEGWSVDPFSGAV
                     IDNIIYGRGVIDNKGAVSMLIHVLKNIEDMYPTINKRIRLIFGTNEETGMKCIKYYLD
                     KGEEIPSMGFTPDAMYPVVNGEKGRVHIRIEKEIKIDKSKPYIIVRGGTKENVVPSHC
                     TAKIINGIISELTTKGVAVHASNPEKGENAISKMVIKIVEDNMDFQHREDIELVSKYL
                     CSDYYGDALGINQYDEVFKNTTLNLGILKVNEEKIVCELDIRYGKNIVLNNIIDRFKK
                     VFCNGWKIEVIAHKDLHYVDESNLVLKKLLEAYEEVTDENGYTIAMGGGTYASWFKDM
                     VAFGPKFLAYKTGGHGVDERVPINHIRKNMEIYTLALIKLLEL"
     gene            complement(26474..26953)
                     /locus_tag="ACGI5H_001898"
     CDS             complement(26474..26953)
                     /locus_tag="ACGI5H_001898"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729131.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-2-amino-thiazoline-4-carboxylic acid
                     hydrolase"
                     /protein_id="HFG9697601.1"
                     /translation="MSEKMYTEKEYLEGIRGATGERAVWFYLLMKEAEKLGANPDDIC
                     KEAIYGFGKMRGQKYNVADTPGKMAEMLYNSKGQKVFEMELVENTDENGVLKFHHCPL
                     DAAWKEYGLTKEERKEICRLACYGDYGRVDCAQGVKLDFAQKCAHDDEVCELVFTKK"
     gene            complement(27000..27863)
                     /locus_tag="ACGI5H_001899"
     CDS             complement(27000..27863)
                     /locus_tag="ACGI5H_001899"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425164.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:1902495 - transmembrane transporter
                     complex [Evidence IEA];
                     GO_function: GO:0016301 - kinase activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA];
                     GO_process: GO:0016310 - phosphorylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system mannose/fructose/sorbose family
                     transporter subunit IID"
                     /protein_id="HFG9697602.1"
                     /translation="MQEIKNKEVKNGQGPTEVNKTRVLTKKDVTKTYLRWWWTAELSN
                     SFERMQALAVCASFTPALEKLYKRKEDLVDALKRHLQFFNTQAIWGGLIHGTVLAMEE
                     EKATEGKIPGEVISGVKNGLMGPLAGIGDTLDFGTFQTIFLALGASFGAEGSVIGAFF
                     PIMFSILLFCEGYYLFHLGYSLGRDSIKKILSGGIVNKIIDGASILGMFMMGALSATT
                     VKLSTPLSFDIGGKAIVVQDTLNMIAPGLLPLGVVFFVYWGMKYKKWTITKLLVILVV
                     LALVGSFIGIF"
     gene            complement(27863..28618)
                     /locus_tag="ACGI5H_001900"
     CDS             complement(27863..28618)
                     /locus_tag="ACGI5H_001900"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425166.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS
                     mannose/fructose/sorbose/N-acetylgalactosamine transporter
                     subunit IIC"
                     /protein_id="HFG9697603.1"
                     /translation="MESVLMLAIVTGLWYWFAAGLAGYTLFSTLKSPLFIGFSLGLLW
                     GDVTTGMIVGASIEMVYLGMVAAGGNIPSDKCLAALIAIPVALQTGVNAEVAVSIAVP
                     LGVIGVLVNNLRRTGNAVLVHKADKYAEEGNTKGIWRCATLYSLIFGFVLRFPIVFVC
                     NFFGADLVQSLLDVIPQWLMNGLTVMGGILPALGFATTIFTIGKNKFLPMFIIGFFMV
                     QYFEISITAAAIFGVCIALLITFMKEDKRVGEV"
     gene            complement(28645..29133)
                     /locus_tag="ACGI5H_001901"
     CDS             complement(28645..29133)
                     /locus_tag="ACGI5H_001901"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425168.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system
                     mannose/fructose/N-acetylgalactosamine-transporter subunit
                     IIB"
                     /protein_id="HFG9697604.1"
                     /translation="MAKITLVRVDHRLIHGQVITKWVKIAQAQKIIIVDDFLGQDEFM
                     ADIYKMAAPSGVEVVILTAEDAGQAFQNNTLGDKNIFILFKNVDMANKAYKAGLKYEK
                     IQLGGIPNEAGKKMVFTAVSLGNEDVEQLNELNENGVEIVLQVIPEESSMTYENALKK
                     FK"
     gene            complement(29151..29552)
                     /locus_tag="ACGI5H_001902"
     CDS             complement(29151..29552)
                     /locus_tag="ACGI5H_001902"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425169.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:1902495 - transmembrane transporter
                     complex [Evidence IEA];
                     GO_function: GO:0016301 - kinase activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA];
                     GO_process: GO:0016310 - phosphorylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HFG9697605.1"
                     /translation="MNKYKVIILCHGTWGKVLVEETNKNFGLSNQYEVLSLSSEKDVS
                     VFMKEVEEVVDKEDVKIIISDLYGGSTSSVAIAVAIRRGIDAINGLSLQTILIVDEEL
                     SKEDKLHTLPERIVKKNNNLCVDLIKEFKKI"
     gene            complement(29555..30052)
                     /locus_tag="ACGI5H_001903"
     CDS             complement(29555..30052)
                     /locus_tag="ACGI5H_001903"
                     /EC_number="2.7.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421032.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HFG9697606.1"
                     /translation="MSLVKYCRCDDRLIHGQVIYKWVKHLGVKKIVVVDDETTNDVIA
                     KGLIKMAAPKNIDLSILTVSESRRYFYNNQADDNVFVLIKNLDTANRMIEEGINIKKL
                     IVGRIPTGIGKKKISQNVYINKKEFLLIDEFIKKNINVSIQMVPDEEEVELNQNINRY
                     KGEFI"
     gene            complement(30076..30480)
                     /locus_tag="ACGI5H_001904"
     CDS             complement(30076..30480)
                     /locus_tag="ACGI5H_001904"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421030.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:1902495 - transmembrane transporter
                     complex [Evidence IEA];
                     GO_function: GO:0016301 - kinase activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA];
                     GO_process: GO:0016310 - phosphorylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HFG9697607.1"
                     /translation="MIGIIVMTHGSFSEEIIKSCELIAGPAERTAAIKLNRNDNIEDL
                     NKNFVEKLNELDEGDGVLVLADLLGGSPSNVASLNLKKGGKFHALTGVNLPMLLEALI
                     NREGKSLEELAEACIEAGQTGINNINKVLSSM"
     gene            complement(30710..33277)
                     /locus_tag="ACGI5H_001905"
     CDS             complement(30710..33277)
                     /locus_tag="ACGI5H_001905"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425173.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0008134 - transcription factor binding
                     [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sigma 54-interacting transcriptional regulator"
                     /protein_id="HFG9697608.1"
                     /translation="MTQKKLSRKEKVLICLKRLTEEHLNFNNGIRFGFDAEYIATEVG
                     INRSNASKELNQLIKESIIIKIKGKPVQYLYKESIESILGKKLNKGIFDNINSINEYS
                     ENDSIKDEYILESIKKENNIFNLVGCDGSLRSQIEQAKAAVIYPPKGLSTLIIGPTGV
                     GKSIFAEYMYKYSLTIKEDSDNAPFIIFNCADYSDNQQLLLAQLFGYVKGAFTGADKD
                     KYGIVHEANNGVLFLDEVHRLSAEGQEMLFLLMDKGIYRRLGEANKVHECRVMIIAAT
                     TEDPETAMLETFLRRIPVTIKIPSLEERGFQERMKLICYFFKEESVRIGVKLKVSKEV
                     IKAFILYKCKGNIGQLKSDIQLICARAFLDYMTYKRECVYVRLSLLPNNIRESLYGNN
                     RKEEFVQNFSFIGKDDIIFLPEEKDFESENLLIENKKYDLDFYGMIKETWNKLQQEGI
                     KESQIRSVIDGDIQKYSYNLMNTFIYNSSNQTAYNNIVNDSIATTVKYILQKHDKWSK
                     REGLDKLIKAIALHIQNLIERIKIGNIVKHPNKDEIMKERAYEYNIAKEILSNMSLMY
                     GVEFPEDEAIFLATFLYLSYVGLNEESIAILVIMHGESTASSMVNVANTLLDCNHAVA
                     INMGLEDRVQDILVQAVEIANKIDKGKGILILTDMGSILTFAKVIRDATGKEVKAIDM
                     VSTPIVIEATRKALTPEMTLEKLYFNIIESIKKHYGDMEVTYAEKDNGGRYFDRLLID
                     NISKTLTFLNGEKAYFILKEVINRISEHYSLVIQDELLVKFIFHCSCMIERVIIKESL
                     VYKSYEERISRNKELYLVIKESFKLVEETFDIIISDMEYANILDIFESQYDTDKFKS"
     gene            33443..34186
                     /locus_tag="ACGI5H_001906"
     CDS             33443..34186
                     /locus_tag="ACGI5H_001906"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729128.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatase"
                     /protein_id="HFG9697609.1"
                     /translation="MNFLSDLHTHSIVSGHGYSTLLENINYCKENGIKILGTSEHGPK
                     MPGSPHRWYFHNIQNIPRIINNIIILRGCEANILDIKGNIDLEPFVIPRLDYLILSFH
                     EAVFSPNTLENNTKALINAINKHDNIEILGHLGNPNYPIDYELIIKLAIEKNILIEIN
                     NCSIKGVSRNGSSDNCKYIATLCKKYGAKIILTSDAHICFDIGNYEYSENILKEINFP
                     DELIMNYPKKLINHFHQKGKLLDVDYTNI"
     gene            complement(34498..34704)
                     /locus_tag="ACGI5H_001907"
     CDS             complement(34498..34704)
                     /locus_tag="ACGI5H_001907"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435950.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9697610.1"
                     /translation="MSKYSSLWEYVKKNNSQSFKLTFEEIKDIAGIEIDHSFLKYKKE
                     LNEYGYQVGKISLKEKTVIFDKIG"
     gene            complement(35107..35502)
                     /locus_tag="ACGI5H_001908"
     CDS             complement(35107..35502)
                     /locus_tag="ACGI5H_001908"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435952.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxamine 5'-phosphate oxidase family
                     protein"
                     /protein_id="HFG9697611.1"
                     /translation="MKALEFLNKAGVYYLATVDENNQAHVRPLGFVMEYNGKLTFCTS
                     NQKDMFKQLIFNPKVELCCIDQNLNTLRILGEAVFVTSKETQAKALEIMPSLGQMYSV
                     GDGKFEIFSIDKAKVSCCSMSGKKIDVEL"
     gene            35643..36035
                     /locus_tag="ACGI5H_001909"
     CDS             35643..36035
                     /locus_tag="ACGI5H_001909"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435954.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="winged helix-turn-helix transcriptional
                     regulator"
                     /protein_id="HFG9697612.1"
                     /translation="MSINTEKNITKNVEELTCPIRYALDIVGGKWKLPIICMLAVENP
                     IRYSSIKRKLDGITNTMLAQSLKDLESTGIVHRKQYNEIPPKVEYTLTSKGKSIVPIL
                     QQFANWGATNMQEKNTCGLSCKECRKIK"
     gene            complement(36135..36551)
                     /locus_tag="ACGI5H_001910"
     CDS             complement(36135..36551)
                     /locus_tag="ACGI5H_001910"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888119.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3788 domain-containing protein"
                     /protein_id="HFG9697613.1"
                     /translation="MNWQDAFFQDTKPTFEQINEFINNPLWDKLNKTLVSTYNVEPKL
                     EYSKCSMQRGWNVKYKKRGKSLCTLYPQEGYFKALVIVSESNRVEVDLFINTCCDYIK
                     KIYNEVNFFNGSKWLMIQVDSLLVLNDMLELIKFRA"
     gene            complement(36566..37477)
                     /locus_tag="ACGI5H_001911"
     CDS             complement(36566..37477)
                     /locus_tag="ACGI5H_001911"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435959.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AraC family transcriptional regulator"
                     /protein_id="HFG9697614.1"
                     /translation="MHAWESIQITLDLIEANLSEEISINELANKANLSPFYYQRLFKR
                     LVNKTVMEYIKLRRLARASEYLAEHKNRILDVALNFGFASHETFTRSFKKAYGLTPEK
                     YRANPVKLNHFIKPELILNYAMVDEGVPLIADDIVIEVNRKTLSNPRTFVGIEIEVPI
                     CQLVGGETTGIAIVEELWMKLGSQRHNIPNQIPGGNEFAALYMGNAKEGNCMYMAGVE
                     VESGTSVEGYSTFELPAKEYLVCGFEAENFNELVNSAVFKADKFMERWMKKHNLTTTD
                     FAIEMYYPTTPEAAYLEHWIVPVPIEQ"
     gene            complement(37659..38681)
                     /gene="splB"
                     /locus_tag="ACGI5H_001912"
     CDS             complement(37659..38681)
                     /gene="splB"
                     /locus_tag="ACGI5H_001912"
                     /EC_number="4.1.99.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421014.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016830 - carbon-carbon lyase activity
                     [Evidence IEA];
                     GO_function: GO:0051539 - 4 iron, 4 sulfur cluster binding
                     [Evidence IEA];
                     GO_process: GO:0006290 - pyrimidine dimer repair [Evidence
                     IEA];
                     GO_process: GO:0046500 - S-adenosylmethionine metabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="spore photoproduct lyase"
                     /protein_id="HFG9697615.1"
                     /translation="MFNPKRIIFEKGTLDTDVGKKIYNKFRDNKDVEIINISSNRIKE
                     HIPGENLYEQYRSGKQTMVVGIRKSLKFQTCKPSANYQLPLVSGCMGRCEYCYLNTQL
                     GDKPFIRVFVNVDEILEQTKKYIEDRKPQVTIFEGAATSDPVPVEPYTNSLKKTIEFF
                     GREEKGRFRFVTKYSDVDSLLDAEHNNHTEIRFSINTPRIINEHEHYTASANKRIESA
                     VKLARAGYQIGFIIAPVFLYEGWKEEYKNLIISIKEALPKDFDKKIIFEVISHRYTTK
                     AKNRILEIYPDTLLPMENEDRKFKYGQFGYGKYVYDKEQLDDMKEFFLKEINGVFKNS
                     LIKYII"
BASE COUNT        12611 a         7044 c         3996 g        15140 t
ORIGIN      
        1 cttaaaaata attcgtcaat acttttttaa attatttttt aaaaatattt actttcttat
       61 attacataat ttattgaatg gcagtcatac tgttggttta gagtatttta acacacacat
      121 tttgttgtaa aaattacaac tattaatata atatatatac aatcataagt attataattt
      181 ttatgaatct aatttaaact taatataaac ttattaataa accttctatg tctaaatttt
      241 aaaattacaa tataaaagct ctacactaaa taaatacatt aaataaacat aatggataat
      301 gaatataaat ttatatatgc aaagcgctcc aataaaaagg taccaataaa gttaaaagaa
      361 acttattgat acctttcatt attacatact tcaatatata attataagtt ttttaaatag
      421 tatggattta catttatccc ttatctcata gctctcatag catttactac tgctataagt
      481 gccacaccta catcagcaaa tatagcttcc cacatagtag ctactcctcc agcacctagt
      541 atcataacta taatttttac tcctagagca aatattatgt tttgccacac tatcttatta
      601 gtcttgtttg ctatttcaat tgctttagat atcttgctag gctcatctgt cataagcact
      661 acatctgcag cttcaatagc agcatctgaa cctaagcctc ccatagctat accaacatca
      721 gcacgagcta atactggagc atcatttatt ccatcaccta caaatgctat tttctctttt
      781 tcagttcttc cttcatataa atcttctaat ctatctacct tttcattagg aagtaaattt
      841 gagtaaactg tatccaattc taattcttga gcaatatttt ttgctacttt ctcattatct
      901 ccagttaaca ttacaacttc ttttacccct atttctttta agcttcttat ggcattttta
      961 ctatcttctt ttacttcatc agagataact atataacctc tatatgcttt atcaacagca
     1021 atatagacta ctgtgcctac ttctttagct gatgaataag atatattttc ttttttcata
     1081 agtttctcat tacctgctaa tataaaattg ccattatgct ttactctaat tccataagct
     1141 gctatttcct cataactgtc tattgtatct aaatcaattt ttttattata gtaacttaat
     1201 atggactttg ctattggatg atttgaattt acctccgcaa tagctgcata ttctaataat
     1261 tcttcttctg atataccttc aggatttaac ttagttacat tgaacacacc tttagtaagt
     1321 gttcctgttt tatcaaatac tactgtatct acacttctta aagcttctaa atagttactt
     1381 cctttaataa ggataccatt tttagatgca aacccaattc cactaaagaa actaagtggt
     1441 attgataaaa ctaatgcaca agggcaagaa acgactaaga atatcaatcc tctatataac
     1501 caatcactaa atacctcacc tgagattaca agtggtggca caaatgctat taataaagca
     1561 gctattacta ctattggagt atagtatctt gaaaacttag atataaagtt ttctgtcttt
     1621 gattttttaa tgctcgaatt ttcaacaagg tcaagaatct tagaaactgt tgattctcca
     1681 aaactctttg taacttcaat actcaataaa gcatttttat ttataacacc tgataagatt
     1741 tcatctcctt tttcaacttc tctcagcact gactctcctg tgagtgcaga agtatctaac
     1801 atagaaactc catctactac tacaccatct aatggtactt tttcaccagg ttttactact
     1861 attatatcac ctacatttac ctcttctggt gacaccacct taacttcaga attaactttt
     1921 agatttgcat agtctggtct tatttgcata agtgaagtta tagactttct ggatttacca
     1981 actgcaacac cttgtaaata ctctcctact ttatagaaaa gcataacccc tactgcttct
     2041 gataactccc ctattgctaa tgctcctact gttgctagag ccatcaaaaa gttctcatca
     2101 aatactcttc cttttgatat atttcttatt gctcttaaaa gcacatcacc acctactatt
     2161 acataggcaa ctataaatac tatattgcta aactgacttt cataacctgt agctgtttga
     2221 tatataccaa atatatatac aagtgctcca attataagtg gaattaattc tttcttattt
     2281 gtatcattta cagctcctga tttttcagta gttctccctt ttactttgtc agtagaccct
     2341 acttgtatat caagccctgg ctctgttgaa tttattattt cttttatttt atttataaca
     2401 tcatcctctt caaagttatt acttatattt actgtaagtt ttttatttac aaagtttaaa
     2461 ttagaagatt caacttcttt taatttagaa actttgttat taatctcttc tgcacaatga
     2521 gcacagttta atcctcctaa tataagctct tttttaattg atgttttact agctgcattt
     2581 tctttagaac ttatttgtat atcaagacct ggctctgttg aatctattat atctattatc
     2641 ttttctatag tagtatcctc attaaaactt tcctttatat ttactgtaag ttttttattt
     2701 ataaaattta aattggaaga tttaacttct tgtagtttag aaactttatt attaatctcc
     2761 tctgcacagt gagcacaatt taatcctcct agtataaatt cttttttaat tgaattattt
     2821 gcttccatat atattcactc ctctcattta tcatttataa gtctctctaa tatgatttaa
     2881 tccacaatca aatatctgac ttatatgact atcatctaat gagtaataca ctgtttttcc
     2941 ttctcttcta aactttacta atctagcctg ctttaatact ctaagttgat gagatattgc
     3001 agaatgagtc atatttaata aactcgctat atcacataca cacatttcat ttgcaaataa
     3061 tgcatataat atctttactc tagtagtatc cccaaatact ttaaataatt ctgctaaatc
     3121 atataacatt tcttcatctg gcatagttga tttagcctct gttactattt cttcatgtac
     3181 tatattacaa ttacaatcat ttatctcttc tctcattttt aatcctccat tattttaata
     3241 tatgaataac tgttcatatg ttcattatat gttatcattt ctaaatttgc aacaataatt
     3301 tttattaatt taatataaat agaatgcaca tattataaac ttttttaata tatatattat
     3361 tagaataagt ttttgtaaac ttttttatag ttttctagga ggtgcaagtt taatatgagt
     3421 aacaagaaaa aaaaggattt agatactagt tacatgcctt acttagaccc agcgaactat
     3481 gcagattata ttactaatga agaaattccc caagatgaat tgagaaatga ccctcaaatt
     3541 tctaatggtt atacaaaaat acctaataac cagaacataa ataacctata tcctaataat
     3601 gtaaatcatt atcctaaaag tagtaattct ccaaacaact tgcctaacac aaataataca
     3661 tccggaaata tgaattacaa tacatctgct acaaataata tgcctaataa catgaataat
     3721 aatacgggta tgcctaataa tatgtctaac aatatgaata gtaatatggg tatgcctaac
     3781 aatatgccta ataacatgaa tagtaatatg ggtatgccta acaatatgcc taataatatg
     3841 aatagtaaca tgggcattcc taacaatgtt cctaataaca tgaatagtaa tatgggtatg
     3901 cctaacaata tgtctaataa tatgaatagt aatatgggta tgcctaacaa tatgtctggc
     3961 aatatgaata acaatatgta tggtaataca ggtatgccta ataacatgaa cagtaatatg
     4021 gggtataata tgaacaatac tatgggtatt cctaacttct catgtaatca aaatatgcct
     4081 cctaatgtac ttatgatgat accaggagtt atatgtcata atacaatgca aggtatgcct
     4141 gtagttatgc ctagtactat gcctcctaat atatatccta ctccttatgg ttctagtaat
     4201 atgtctatac aaggtatacc acaggctact aatattgagg aatttgatga ggaagaaatg
     4261 taatatatat ttttttaagt aagttgtata aaacattaat aattgaccat aataataaat
     4321 gtattcctca taatattccc ccaatattat tataggtata gaaagttgac tgaatatgcg
     4381 cttattcggt caacagatat taacataatc taataagata aacatagaaa aagtcagata
     4441 aaatttaatt ttatctgact ttttcattta aaaatgctct cttgtattgg tgggtcagaa
     4501 tagtatgata ctcgtatttg agactaatat tggcaaacaa cataaagaaa aatataaatt
     4561 ttttataata aactgtataa aattttaata attgaccaca ataataaatg tattcctcat
     4621 aatattcccc caatattata gaaataaatt taagcgagat taaattcagt taatctcgct
     4681 taaataatgt ctaaatttat tattccaaaa aatcatcaaa atctaatgaa cctgattctg
     4741 caaaatcata taatgcattt tgctcaaaga aaaatttctc ttcaaattta atatagtcgc
     4801 tataattaga ttgacttatt tcattgatat aattgcaatc attttcgtta taagtaccaa
     4861 taaaaaactt atttcccatt aagtaatata tagctttcat atcattattt attatatata
     4921 cattttcttt tacatggtca ttattaaaat taaatctagt aaagaatata ccttcattca
     4981 tattactttt taacagaaat ggattttctc tataaaatac tcctgcaaat tcttcaggtg
     5041 aatttacact gtaaacactt acaaattcac ttttagaaat ctcatcaaat acctcaaaat
     5101 catacatagg ttctttatct gtcactaata gagaattaat tctaaaacca gtttcataac
     5161 acttacttat gcaaaaagca attttacata tataatatcc atcattatct tcatataaag
     5221 cttcacttat atatctgcct tgacctttat cacttaccac gtttttaagt aatgttccat
     5281 ttatattagt aatgtgcata tttgcaatct cgtcacttcc agaaaagtac tttaaacttt
     5341 ctctatccca tgctataaat ctcatggtca tatagtttat aaattcaact tcctcgtcaa
     5401 ctcttttaca tattttattg tataattttt ctatagttaa atctgtttta tagtttttta
     5461 taatatcaat atactcacat ttatctcctg gcaatagctt atcataataa agattcttat
     5521 taccaaaata agatactaaa aataaagatt catccttcgt taattcaact ctatctgaac
     5581 caaatcctcc catcaatctt tcttcttcca tataagcttc ttcttgtgtt gggttattta
     5641 aactcacata atccgctaat cctaatccct ctgcatctaa taaaaaatat tgacaaaagt
     5701 gattgttttc atcatctatc caatttatta taagacctaa actgcccata agtctagaat
     5761 ttgtagcctt tgcaaaatta aaattcatat agtcacatcc tttaaactct aaaatacttg
     5821 ttttttaata tataaattat tatacatata ttttaacaac ttagatacaa tttataatat
     5881 aatataagga aatgattaat tgaggtggtc ttatgaaaaa tatagcagct ttttttgata
     5941 tagatggtac tctttataga gactctctta tggttgaaca ttttaaaaaa ttaattaaat
     6001 acgatataat tgaccaaaaa aattggtata aacatgctag agacactttt atggattggg
     6061 ataaaagaca aggtaattat gatgattatc tattagaaat atgtgacctt tatgttgatt
     6121 cactaaaagg attagataaa acctgtatca actttacaag tgaccaagta attaaattaa
     6181 aagcagatag agtttataaa tacacacgtt caaggattga gtggcatcta aatcaaggac
     6241 acatagttat atttatatct ggtagccctg gatttcttgt tgaaaaaatg gccaaaaaat
     6301 ataatgtaac cgatttttta ggaagtgatt atgtctttga aaacaatata tttacaggca
     6361 cagttattcc aatgtgggat tctataagta agaataatgc tataaacgat tttgttgtaa
     6421 agtatgattt agatttatca aactcgtatg cctatggaga tactaatggt gatataaata
     6481 tgctaaaaag agttggaaat ccaatagcaa taaatccaac aaaggaactt ttatctcaaa
     6541 tatcacttga tgaggaaatt tctaaaaatg ttgagataat agtagaaaga aaagatatta
     6601 tttattctct atctacagat gtaaatatag tggatattta atttatacta tctattttaa
     6661 aaacttatat tatatctaat atttatatct aacatataaa agctttgact aaaaatcaaa
     6721 gcttttatat gttgcactaa gaatatatta aatttagctt tatgctttaa tgtatattca
     6781 tatatatcat ttacacttat ctaaactaca atttcattaa aattaaatat aaaaatcaac
     6841 tattattttt taaatagcat ctttcttaat ctattattgt aataacctat aaaagaactg
     6901 taaacatagt catatactat aaaggctatc tcaaatgaac ctataataaa tatgtttatt
     6961 ggaatataaa ctattgttct taataaaaaa tacaatataa gtatcattat atttgcaaat
     7021 actaatttca taaaatactc aatatatata gacctatctt tttctataag atattttaca
     7081 ataccatata ttccaaaggt aagtgaatat acaatccatt gagacttact tgccatcact
     7141 ataaatccta aaactataga acctatataa aaagcaattc cactcttaaa gccccattcc
     7201 attattacaa ttgatactaa aagtgatgct aaccccataa taaacaatgt atttacagga
     7261 ataatatttg taagagtcaa caatatcaca tttaatgcta ataaaactcc tccataagca
     7321 acttttatac tcatatttat catcctaaca acaagttatt aaatctccac caaaacattc
     7381 acaacatgaa tctaaacacc aaagcttagc acaattttca caacaatcgt cacctagaca
     7441 acaacagcaa tcatcacagc aacagcaaca acatccatct aaatcattac gtcttcttct
     7501 attataattg tcagccctat tgctataatc atttctatat tgtgtataac ttctaagtgc
     7561 atcactatat tcactatttt caggctccat aaattttgct ctttttaaga agtcttcacc
     7621 ttcttcataa tatcctatgt tcattgcaga aaagccagtt aaataatacc actctgcaca
     7681 tttgtcagtc aaagttttta aaaaatcata tgctttttta aattcactat tttctatgaa
     7741 tgctcttgct ctcataaaat tttcattatt ataagtatta ctgtacattc tttccacctc
     7801 tactttctaa tatattaata tatcttaaat aaacaccaga ataaattata ttttctatta
     7861 ttccaacatt tttatttaga tttagattat caattcccct agctaaaaac cctaatgatg
     7921 ttactattat tttttttact ttttctttta actcatcatt tttatcaata tactctataa
     7981 atggattata tcttcctttc ttaaaatctt catctaaatc ttcataggca tctagtagat
     8041 atatatactt acctatatta aaacctatca ttcttaagtt tctctcattt tcatcttttt
     8101 tatagacaaa tacttcaccc attatatttc caaatatact agatacttca tctatattta
     8161 tatttttatc tttttctaac ttatttaatt catttagttg ttgttttata tactctgctt
     8221 tttcaggata cttttcatat gctaatttta atttgttttt atatatataa tatgccaatt
     8281 tatcttttat gcgtttatca tccattaaat tatcttccaa tttataatac gttaaaagaa
     8341 tattcatact tgctgcatat tctgtaatat catttgtaat tacctttttc tttttaaatg
     8401 gatttactat acacacttcc tctgtactta tagactctgg gttatatact gctgttaata
     8461 aaacaattaa aaatgttata tcataattca aagaaaacct agagatttct ccatgatttc
     8521 tttttaaata tttacatagt ccacaatagt aagctttgta ataatcgtat tctctaaatg
     8581 ttaaatccat tttgtttatt ttaacatatc caaacataaa tactcctttt tgtactattt
     8641 tttatttaga ttatatatag tataacactt tttatcaaga ttatataatt tacagtattc
     8701 taagaaactt aaaaaattcc ttctaatcat tgtatcttaa atttaaaata attagaaggt
     8761 tgggttaaaa ataatattaa attatatact tatattaact catacaagtt agttgtgctt
     8821 atatcaattt aagttttaaa taattggtat atatttaaaa ctacctacag tatccttcaa
     8881 ttcttttttt gctttattta taaccaattc atcaagcatt acatcattta ttgaacatga
     8941 tatagattta gatgccaata acattgcttt aaatcccata tcagaacctg cactggcaca
     9001 agattgccat gtatgggcag aaataccaat aggccaaact gaacaagaac actgtgctgt
     9061 aggaattatg taactaacat ctccaatatc caatgataat gatatacagt tattatgagt
     9121 aaatgtatca tccgtaactt catcatgcag attcatctta gtaatatcct tatttccact
     9181 taatacacta gaaacactac ttcttttatc tatagacact gtctcagcta atttatctgc
     9241 aaaatagtag tcatcttcat tatagttttg tacacctact aatttcatat tttgtgatag
     9301 aatatctgtt aatattgtat ttggaatata gtcatatact ccacttataa tgtcatattc
     9361 cataatagta ccagtcatta atgctgctcc ttttgctata tcaacaatcc taccaaatac
     9421 atctcttaca tgctccattt taactcctct tatgtaatac cacacttctg caaaatcagg
     9481 aactatattt ggcatttttc caccattagt agttacatag tgtactctac aattatcaaa
     9541 tatatgttct ctcaaataat tacaacctat attcataagt tctactgcat caagtgcact
     9601 tcttccgtta taaggagctt gtgctgcatg ggcactaatc ccattatatc taaatttcac
     9661 agagtaatta gcaagtgttg ggattcttat aggagtattt atatcaaatg gatgccaact
     9721 aaaagcacaa tcaattccat caaaaaaacc tttttttatc atcaatactt ttccagataa
     9781 atcttcctct gctggacatc catagtattt tatagtccct ttcagctttt ttagtttgat
     9841 taattccttt actgcaatta cagctcctat tgaacctgta cccagtaagt tatgtccaca
     9901 tccatgacct gcaccaccat ctacaatagg ttctttaata gtggatactt tttgagacaa
     9961 actatctaaa gcatcatatt ctcccaaaac tgctataact ggtctacctt ctccatagct
    10021 agccgcaaat gctgtatcca taccttctaa ttcatctata ctaaaaccat atttttttaa
    10081 gtattctttt tgtaaatttg aagcataata ttctttatac tgaagttctg gatttttcca
    10141 tatcttatct gatatatctc ttaattctcc ctgtatctca tctatatatt ccatcaaaaa
    10201 ctttttattt aaattctcca tattaattat ataaacctcc ctgtttctaa taacttatcg
    10261 attatcagcc aaaatgacta attttaactg atttaaaaat attttctatc atacaaccat
    10321 tttatacaat aaaacctctt gacttgtaag tttcatttta tcaagtaaga ggttttcaag
    10381 ttttataaaa tttttagcat gttaaccaat caagcatatt aacccataat ttattatagt
    10441 atttccaatc agtaaattct tttggacccc agtgaggtgc acagtcagaa ctaaagatag
    10501 cagattttcc ttttccaaac tcgccaacag ctacaaatgg gtctcctcca atagttgcta
    10561 aaacaggaca attatctcta gctactgttt tgttatatcc taaaaacttt ggccattctg
    10621 ttggtatacc ttttaatact ggatgtttag agtcaataac ttctggaatt attcctgctg
    10681 gtttttcaac tctatcatct ttatctatca ttgttattgg taatacatct ttgatagcag
    10741 tttctccgaa tctagctttt gcatctattc ctgtaaatga catatatcca cctaccatga
    10801 ttaacgcccc accattattt acatactctt tgattagttc aagtctatct ggattactat
    10861 tgcaatctat aaaagtacta ttagataata agaacgtatt agaacctata tcagataata
    10921 ttatacagtc atactcattt aactcttcta atttatacgg aaaactatct gctgctacat
    10981 gtgcaggcat atgaactgtc tcatatcctc cagattctat tgcttctttc aaccacttta
    11041 cagcttcttc ataatgagtt gtaacaaacg tatcaaatcc ttttatatga gttatatttt
    11101 ttacccaaga ttcccctact attaatactt ttttcattta tatattcctc ctacttttat
    11161 aagtttaata ttagacttgc atacataagt atactatcta aatactcctt aatttcaaca
    11221 tattcatcaa ttgaatgaca ttgttctatt gaacctggcc ctaatataag tgttggtatt
    11281 tcagctaaat ttttcattaa tctcgcatca ttgccagctg ttgaaccttt tatctctaat
    11341 tttttcccta gagtttcttc tagtatttta tgtgcattca ctacaaaatc agaatccttg
    11401 tccatctcaa aacctaaccc tgattgatat atgtttatat ttggtttatt atctttaagc
    11461 cataaatctc cattagccct tgtcattatg acatttgtta catcatttac aacttgttca
    11521 taactcatta tatttggcaa gaagtgtaca cataaattaa atacacactt atctggcaca
    11581 gtagaacctg ctgttccacc atttattaca cctaaattta ttgtaggtga aggtaatagt
    11641 ggatgtttat atatcataag ccagttatgt tccaactctt ttatatcttg aagcaacaac
    11701 atagccttct caattgcatt tacaccctcc cacttactac cacagtgaag agacacacct
    11761 ttaacctcaa cttcaaagaa tacaaatccc atatgtgcaa ctattaagtt ttgttctgat
    11821 ggttcacaaa ttatgcaaca atctccatca ataccattca taactgcatt tatggtacca
    11881 tttccgccac cttcttcatc tactactgac attattttta cattaccagg tacatttaga
    11941 ccactatctt ttataagctt tacagctaat attgatgcta taagtccaga tttcatatca
    12001 gcagttccaa gtccataaag ttttccatta tcttctgtag cacgatatgg attatatttc
    12061 cacttactta tatcacctgg tggcatagtg tctacatgac cattaaatac aattgtctta
    12121 ccaggtaaat catcactata cttacaaatt aaattatatc tatcttgata attgtgacct
    12181 agatttcctt ctttatatat attttttgct tttttaatta attcttcgct catttcttgt
    12241 ctatctacac taaaacctat gtaatttgca agtttttcaa tatattcctg tccttctttt
    12301 tcaaatccac ctagtattcc atgaccaaca tcttcagtct ttatacttac aagttctttt
    12361 aaataatcta tgtattcttg ttttttacta tttaatgtat ctaagagaat ttttttcata
    12421 tttcctccta agatttattt ttacatttaa aatttcaagt ctaatctcat ctatttaagc
    12481 catagtaaac tttttcactt agcatattcc cattcaatgt ataaagatgt atgcaaatta
    12541 aagtataaaa atatatacaa aaacttaata atttttatag tttataagct aaaatttaat
    12601 tactatttag atttagctga tttttttaat tttatattat ttatccatat agcaaataac
    12661 attaccaaac cttttataat catttgatta tatgaagata cacttaataa gtttaatcca
    12721 tttcctaata ttcctattat tccgacacct atacatgtac ctactataga accagaacca
    12781 cccatcatat tagtaccacc aagcacaacg gctgctatag catccaattc tgctccatct
    12841 ccaacagttg gtgaacctga tgccaaacgt gatgatagta ttatcccagc taatgctgtt
    12901 agtagtccag ctagtgcgta tacttttact ataactttat ttacttttac tccacataat
    12961 ctagcggcct cttcatttcc acctactgca tgtacatgac gtccaaaatt agttcttttt
    13021 aatagaaaat gtcctgctat tacaactata atcataatta taactggtat tggtattggt
    13081 ccaatatatc ctctaccgag catcttaaat gcatctgtat ttactgatat aggtcttcct
    13141 cctgtaaata caaagcttgc cccacttatt atcgttaaca tggctaaagt tacaatgaat
    13201 ggaggtagtt tttgtgttga aataattgca ccttttatga ctcctaaaat tgtccctatt
    13261 gctaatgcaa gtatcatacc tacccatata ggtgcattat aattcactac tgttgtagcc
    13321 caaaatgtac ctactaaagc aattactgct cctacactta aatctattcc tcctgtaatt
    13381 attacaaatg tcatacctac tgcaagtatt gcatttattg atatttgtct tccaacatta
    13441 attaaattat ctaaagttaa aaagttagat gaagctacac tcattattat aaaaattatt
    13501 acaagtccta cagctgcact cccttggtct ctaaatacac ttgttaattt tgtcaataat
    13561 ggagaagatt tttcttcttt atgcttagtt attgaactca ttaattttac ctccgaaagc
    13621 caattttaat acattatttt caaccatttc ttcaccttct aaaaatccac ttatatgacc
    13681 ttctctcata accattattc tgtcactcat tgatattaat tctggtattt cagaagatat
    13741 cattattata cttacaccac tctccactaa atctcccatt agattgtata tctctgcctt
    13801 agcatttaca tctatacctc tggttggttc atccataatc aatatatctg gttgtaataa
    13861 aagccatctt gctattatag ctttttgttg gtttccacca cttaaacttt gtataacttg
    13921 attcatatgt ggtgttttta tctttaaagc ttctatgtat ttttctaaaa tctctttttc
    13981 cttttttcta tctataattg atttaaactt agatatcttt tttaacccag ccatagttgt
    14041 attttctttg acactcattt gtaaaaacaa tccagtacct tttctatctt ctgttattaa
    14101 tcctagtcca ttttctattg catctgatgg agttttaaac tttacttctt cattgtttaa
    14161 atatattttt ccagaatcat atgttctaag tccaaatata gcttctacta tttcacttct
    14221 cttacttcca actagtccac ctattcccaa tatttcacct tttcttatat taaagctaat
    14281 atcattaaaa acattgttct tagttagatt ttccactcgc ataatttctt cttttatttc
    14341 tacttttctt tttgggaaaa attggtctag ctttctatct atcattaaat taactaattc
    14401 ttcctcagac gatacatctt tggtatttaa agtcgaaatc gttttcccat ctcgcattat
    14461 agttattctg tcacaaatct caaagagttc ttccatccta tgggatatat atattatact
    14521 aactccactc tcttttaaat catttataag tctaaaaagt atttcagtct cttttttact
    14581 tattgaagaa gtaggttcat ccattattaa tactttagtt tctgatgata aaactcttgc
    14641 tatttctacc atttgttttt gagctatact aagctctttg actaaactat ttggatttat
    14701 atctattccc atattatcga aaatcttttt agcttcttca ttcatttttt tgtcattggt
    14761 taagactttg ccatttattt cttttcccat aaaaatattt tgtgctactg ttaattcgtc
    14821 aaaaactgtt agttcttgat atatggcatt tatacctatc tttttagaga tatctgggga
    14881 tatattctct atttctttgc cttcaaaaat aaattttcca gaagttttcg aatgtgcccc
    14941 agttaaaatc tttatcattg ttgatttacc agcaccattt tcacccagta gtgcatgaac
    15001 ttcgccatga aataactcaa aattaacatt atctaatgct ctgacaccag gaaattcttt
    15061 agcaatatta cttaacttca gaattatatt actcataatg acactccttt ttaaatagga
    15121 tttctttcaa ataatctcat tttattttac taattcttaa agtcttttat attttcctta
    15181 tcataaagta aagctggtac tggtatattc ttttctacct tttccccttt tatagctttt
    15241 actactgctt ctacagctaa acgtcccatc tctttaggtt gttgttgaat catagcaaga
    15301 atagttccat ctgttattcc acttgatgct tcttcagtta agtcaaatcc tacaatctta
    15361 acatccttat tttttgcaga ttcaagtgca gctttagctc ctagtacact attttcagct
    15421 gttgcatata ttatatctac atctggatta gattgaatta agttttctac tgtattaaga
    15481 gattcttctc tgtcatatcc tggttgtgaa tttaatatct taacatttgc tgaacctttt
    15541 aatgcatctt taaatccatc tattctctgc atttgtattt gagattttaa atctgtcact
    15601 attgctattt ctgactttcc acctaacttt tcatctatgt attttttagt gtattcccct
    15661 aattttttac cagcatcata actaactgtt cctacataac ttgtaatatt ttcagtattt
    15721 aatacagcat ctactgtaac tactggcatt ttttcaaatg ctccttctac tgctggtact
    15781 atagccgaat tatcagttcc aagtactatc attccatcta cattctgttg tataaaatct
    15841 tctattgctg atgtttgctt agctacatct tggtctgggt catttactat aactttcaca
    15901 cctaattctt tagctttttc ttttattccc tcatcaatat ctataaaaaa ttgatgttga
    15961 agagttattg tagatactcc aatagttaaa tctttcttgt ctgaaccacc tttattatct
    16021 gatttacttg gtccttccat tgaacaccct gttaacattc ctattgctag tattccagca
    16081 attcctaaag ataaaatttt tctcactctc ataattaacc tccattttta atagttttaa
    16141 atttgaacaa attagatttt tatttattat ttaaatactt ttcaacatct tctttatagg
    16201 gcataccaga ttgtgcacct agtttagtta cagaaagacc tgatactact actgcatatt
    16261 ctactgctgt atataaattt ttcccttctg ttatagccac tgccaatgct ccattaaatg
    16321 tatctcctgc tcctgtggta tcttgaacat caacacttat acaagataca tgcttgattt
    16381 cctcaccatc ataaaatcta gctccatttt ttccttctgt tattacaagt ttatttggat
    16441 atttttttaa tacttcttct atcccttcat ttgtgtcaaa aactatctta tattcatgtt
    16501 catttggtgt taagtaagtt actttttcta ttatatcttc atttagtttt actgctggtg
    16561 ctggatttaa taaaacccta atcctatttt caaaacagaa attcactaca taatttattg
    16621 tttttaatgg aatctctaat tgtagcaata ctatatctgc attctttatc tcttcttcat
    16681 tctttttaat taattctata tctactagct cattagtccc tggtacaaca acaatactat
    16741 tatcattttc acataatgtt ataacagcaa caccagaact tttgtgatta tttctggata
    16801 ctaagctata atcaacttta ttcgttctaa aatttcttat taactcctct cctaagccat
    16861 cttcccctat gcatgatatc atttttacat ttgctcctag tttagaagct gagatagctt
    16921 gattagcccc ttttcctcca ggtgatgtaa aaaaactatt acctaatact gtttctcctt
    16981 tttctggtct tttatctaca gaacatacca tgtccatgtt tacacttcct atgacaacta
    17041 tatttcccat tacattactc ctttacatat ctatttatgt ctctcgtgct gttattcact
    17101 ttcttttgtt gaatctctta tgaccaattc tggtttgaaa atcaattcat caaacgattc
    17161 ttttttatct cctcttaaac aatttatcaa tatttcactg gctttatatc ctatatcata
    17221 agacggctgt tttactgtgg taagagaagg gcttattaga cttgatgttt gaatatcatc
    17281 aaatcccacg acacttatat catttggtat acttaatcct ctttctttaa gacctcttat
    17341 gacacctatt gcaatcaaat catttgcaca aaatattgca tcaaaatcta tcttttctaa
    17401 attttttata aattcttgtc cccattcaat cttatatttt ccttcaaata cataagcagg
    17461 attgtagctt aaattacact cgattagagc ctttttatat ccttctaatc tatctactgc
    17521 tatttcattt tgaagtggac cacttaggta tattattttc ttatttccaa tatctaataa
    17581 atgttttgta gctatatagg ccccttcaaa gttatttatt ttaacaattc cttttaaggt
    17641 ttctttgttc atacttatct tcttatcaat caagacagtt ggtattttta tatctttata
    17701 atttgcttct ttccagtttg tatttgaaga tgctgcaaat ataattccat ctatcatcct
    17761 ctctgatagt gttcttattc cttcatattc ttttttagca tcttcatctg tattacataa
    17821 aattatattg taaccttctt cattagcttt gtcttctaca cctcttgata catctgtaaa
    17881 gaatggattt cgtatatctg gtataagaag ccctatagta ttagtttttt tagttactaa
    17941 actttgtgct aatttatttg gtacataatt tttttccttc attattttca aaattttttc
    18001 tcttgttgcc tgacttatat tttcatcttt attattaatg acttttgaca cagttgtttt
    18061 agaaacacca gccaattcgc caatttcttt tatagttata ctcaagaagt tcacccccaa
    18121 aatttaggaa accgttttac ttaaccggtt acctagatac tatcacatct tttttccatt
    18181 tgcaaccatt ttatataaat tttgatattt ttcccttttt tcaaaatatt gcaacttata
    18241 attcaatttt aatatttaaa ttaatctgca aaaaaaaatt aatatacttt tataattatc
    18301 taaaagtata ttaattaatt taagcagtat ttattaaagt tcaaatcctt gctctataat
    18361 cattttttta tcattttcaa tcccacttcc aacagttgtc aaataatcac caacaattgc
    18421 agaatttact cccccattaa atccaacttt gtcatatccc tttaatgata gccttccacc
    18481 agcatacctt atgtacacat taggaattat aaacctaaat actgctgttg tttttagtat
    18541 ttccattggt tctaatacat cataattttc cattggtgta ttcttaatag gatttaaaat
    18601 gtttattgga aatgatttta catttaattc tcgtatttca aaagccattt ttagtctctg
    18661 ttcttcactc tcattcattc caattatacc acctacacat acatctagcc cagctttttt
    18721 agcatctttt atagttttta tcctatcttt atatgtgtgt gttgtacata tattatgaaa
    18781 attatctcta cacgtctcaa cattgtggtg atatgtagtc acacctgctg acttcaacat
    18841 tttagcttgc tcataatcta taatacctaa agatgcacat aattttaaat tagtattttc
    18901 cctcaatcct tcatagatat ttaaaatatt attaaactcc tttcctgaca tacctttacc
    18961 acttgtaacc aatgagaatc tatgcactcc tttactctcc atctctttag ctctatttaa
    19021 gatttcattg taatctaata atgaatattc ttctacacca gttttataat gagatgattg
    19081 agcacaaaat ttacagtctt cactacattt gccagattta gcattcatta tcgtacataa
    19141 atctgctttt cttcccataa aatattctct tatttcattt gcagatttta atagaatatc
    19201 aaaatcgttt ttattatttg tatcaaggct tattaaatta agagcttctt cataacttat
    19261 ttctttttct ctcaatactt tattttttaa ttttattatg tatttttcca tatatcctcc
    19321 tatttgtcaa cttaatattt ttatgtagtt tacttattat atatagtatt gcatatataa
    19381 catttattgg tcaactttat tttagacaca agtttactat acacaaaaaa atactgcttc
    19441 aaaataatat tagtaaatgg attatacata ttattattaa aacagtattt tttattagaa
    19501 tataattctt actggtttat aaaactatcc ttgtcttaac tccatccaag ctttccattg
    19561 taataacctc taagccttca tattctctaa atagccattt taaatccttc atggcttgat
    19621 taacctgact ttttgttaga ttatttataa aatattcttt tctagtttcc tcatactctt
    19681 tgctagtcaa aaagtttctt agaaaattaa acgcaaatac acttggaata ttgtttacat
    19741 tagccttctt gctgttttcc ttctcatagt aaattttcat aaatgcatac tcctttgata
    19801 cttttagatt tctcttacaa taattatatg catttaagtg ctactattct tataatttta
    19861 ttaattcata ttctttactt cccataccca tttcacatgc atagtctatt attctagttc
    19921 catttacatg aggatgttca tgtttgaaaa catcatgacc catttcctta caaatcaaat
    19981 catagcatgc ttgttcaata gctacagggt ctgttgatgc taatattcct atatcatggg
    20041 caattggtct acctgaccaa ggtacacaat cacaaagtgg agttacattc ataacaaaag
    20101 ttatataccc taccttgtct tttttatttg atactgctcc ataagcgtat tctgccatct
    20161 tttcgacaaa cacatctgag tcactttccc attgtatagt tactgctcta gttggacaga
    20221 cagttggaca ttctccacat ccataacata catcagaatc tataactgct tttttatcca
    20281 ctatacttat agcttttgta ggacaagaat taacacactt tccacaacct acacacttct
    20341 tttcctttac tactggagta acatcagaat gttgcatttg ttttcctgct gcacttgcac
    20401 atcccatagc taagtttttt aatgctcctc caaaacctgc tgcttcatga cctttaaaat
    20461 gactcattac tatcattgca gaagaattat aaatttctcc acctattttt acactttcaa
    20521 aatgtttttt gtctattttt acattctcat aatttctact atataatcca tctgcaatta
    20581 ttactggtgc atttacaact gcataagcaa atccattttc tatagcagtt gtaagatggt
    20641 ctacagaatt tgttctactc cctgtataca gtgtatttgt atctgttaaa aatggctttc
    20701 cttcgcagtc tttaacctta tcaaccactt gtctaactgc cacaggactc atatatgtag
    20761 tatttccctt ttctccaaag tgaagtttaa ttgcaacttg gtcattcttt tctattaaat
    20821 ctttgaatcc tgcttcatca aataatcttc ttacattgtt tggtacgttt ttattttgcg
    20881 aatttgagta taaatcacaa aaatatactt ttgacttttc catatctaca cccctttaaa
    20941 atatttactt atactaattt tatcactttt aaagtaattt ttagtatatt ttaacataat
    21001 taaatattct tatatttatt tgatacaaat aatattattt gtattatttt ctacacttaa
    21061 ttctatatat taaaaatcaa aaagacttga aacttaagtc caagtctttt tgatttttag
    21121 gtgtagtttt taacaacata agattacttt accttgtgat aaaggtatta ttaaactggt
    21181 tttttattaa ataaaataac agctgctagt aaacatacta cagaaataag aactgttata
    21241 ataattggaa taataaattc tggcattgcc actttccctg aaatcaagtc tatatttttt
    21301 gacatcaaga aattaggagt ataaggtgca atctgtttag gaatagaaat taaactcaat
    21361 aaaagagttg ccaccaatac aagtaaaaca ctggcaaatg ctggtctaaa tagtacacac
    21421 ccaagaatta atacactaat atacataatt cctataagcc ataaattaaa tgctgaaaat
    21481 ataatatgat taagatttgc agttggccaa aaatatattg tatagccata agcaaataaa
    21541 aaactcaacc aaaaaccaat tgtcataata atcaccgtaa cagagaattt agacaatact
    21601 atagatgaac gtgataaacc tttagtcagc ataataacaa gtgtcccttt agaatattca
    21661 tttgataaaa tattacaaaa aataattaga gttaaactca taccaagacc agagatattg
    21721 ctaaaaaatt gtgtccaaga atctaaagca gttggtgcag cagtaacttt taaagtcggt
    21781 gcaaaatgag caatcaagtc tggcataaat tttgcagaaa taggactact tataccaaat
    21841 attagaaata aaataattaa actaaataat ttataatttc ttaaattctc tttaaattct
    21901 ttttttgtaa atgctatgta ttctctcact ttactacctc caaaaataaa ttttcaagtg
    21961 ataattctat tagttccatc tttactggac aaagattcat ttctgcgagt gtagatataa
    22021 ctgttttttg tattgctttt atatctttac catgcaaaac aatttccata ttagtttctt
    22081 ctgaatcttt tagtaaggat ttaataccat cactagactt aaacttttga atttcatcat
    22141 tacttgcaaa ctccagtaaa agtctatcct ttccgtgcat actttttatt tctgaaagtg
    22201 taccactaag ggcaatgctt cctttgttta atatagcaac atggtcacag attctttcaa
    22261 catctgatag tatatgtgtt gaaaatatta cagttgttga gtctttgatt ttaagcataa
    22321 tatctaatat ttcttttcga ccaacagggt caagtgcact tgttggttca tcacaaataa
    22381 gtaatttggg gcgtgaaagc aaagcttgag ctataccaag tcgttgcttc attccacgag
    22441 aaaacccacc tattcgtctc ttttcatttc caagacccac aagtgataac aactcttcac
    22501 tccttatctg tatttctttt tttgaaagtc ccgtaatttc accacaaaga gaaagatatt
    22561 caagtggtct catatagttg taaaactctg gaacatcagg cagataacct acatgacgat
    22621 tagaacttgt tttcccatag gtcactttct caccacaaac atctatagtt ccactatctg
    22681 gtttaagtaa cccaagtacc attttcattg ttgtagtctt acctgcacca ttcttaccta
    22741 caaacccaaa gactgaccct tctggtacag taaaatttaa attatctatt atctttcgat
    22801 taccaaaacc ttttgataat ccatttattg agacaatatt catcattctt cacctcttcc
    22861 tattgtaaaa tacaaaattg gtcctattag actaataaac agtactacaa taatccatat
    22921 tgccttattt ccaattttat aatttggatg tctcaataca tgaacaagtg cagtaattat
    22981 aagtattaaa tctaaaataa taacaggaac caaaagtggt aagtattcca tcaaattttc
    23041 cataatctta ttcctccaat aaagataatt tttctataag aaatttgtat tctttgtttt
    23101 cacttaatac agaaaacatt ggattatttt taatagcagc aacaatacct gcttttacga
    23161 ttgtatcatc acgtgtaata cctgttccaa tttcagaaat ccatctgtca agtttattaa
    23221 aaaagtcatc cccatgtatt ataattgggt atatatcacg tgttgctaaa tctacatatt
    23281 ttcgtaatga tttaatagct ccttcattat caccatgtat taaattaatt tgtgcctgtg
    23341 ttaaatatga agaaagcata atagcaggag ataatgtatc aagctcaaat atatctgaaa
    23401 ttgctagaat acgtctttct atttccttca tttgtaattt atctgcattt tgcaaaatac
    23461 ccactaggtt ttggactaat gatataaggt tctgatatgc accaagttga aatgtttctc
    23521 tcgcttcatc catttgacca ttcatcattt gcccctgtgc aagaagtata gattcattta
    23581 tcatgggaaa attgctgttt tgcaataaat caatcacttg tatgggttga tttaacaata
    23641 tataacaagt tgcctccata ctttttgctt gacggcaaat atctatgtca ttacaagttt
    23701 cctgtatacg aataaatatt tctaatgctt cactaattaa tagttcacgc tttttttcat
    23761 ctacaatatc atagtgatta actattaaaa gacccatccg aaaaatcaaa ggaaaacatg
    23821 aataatattt ttttatgatt tctcttattt catccatgac ttcatcaaat ggtttaaccg
    23881 taaagtcttt gcacagttta ttatacagtt tattaatatc ttccttcatc atttgaggtt
    23941 cataacatat taactcatca acggtaatgt tgaaatatgt cgcgagttgc ggtaaaaaag
    24001 ttatgtcagg atagctttgt ccagtttccc atttagatac agaagcttta gaaacgccta
    24061 tataatttgc aagttcatct tgtgtaattc ctttttcttt acgctttaaa atcagcgttt
    24121 ttgcgatgtt taattcattc atgtcaatcc ctccttatgt ataattatat ccttaaacat
    24181 gtaaagctaa caagcgattt gaagttgact tttgacgaaa aaatcaacca cagagaaaca
    24241 aataaacaag tatataaaat atatatttaa atttatcttt aatctctttt gtaaaatatg
    24301 taaactttgt aaataaaatc catattatat aaaactaata gttaatctat ctaaatacag
    24361 tttttattta tcacgttttt aaatattttg tgtaaaacct cttttaatat aaacacctta
    24421 ttttcatttc tcatttcata ttctttttaa aatactgaat ataactcttc gattttccat
    24481 ttaattcttt tataaagtta ttattcgtat ttatttctct aattataaca ggcaactatc
    24541 atgtattggt atttgtctat tatataaaaa tctataaaag aaaagcagtc aatcatttag
    24601 attaactgct tgtacatata tcttattaaa ctgtataaac tataattttt attattctcc
    24661 attttcatcc caagtcataa atccccatcc actatctgga taagtatcaa tagacttttc
    24721 tctaatcata taaccaactt tataacactc ttttgttatt ttattagata gtatacatcc
    24781 ttctccattt atctaattcc attcaattaa cttttctttt caaccttaac ttttataaaa
    24841 tcatcttttt taataatttc atacttattt tctcttcaac atcatcaaat gagggtgtct
    24901 caaaattaac tttttacttc ataaggcact cttttttgta tgaagtaaaa tatattttca
    24961 tcatttcaac aataagtaag aggcttatct ctattttgag acagccccat ttgatggtgt
    25021 tgaacattta aataaggttg aactcgtttt atctctcttt ttaagatatc tgtaaatttg
    25081 cacataaagt ctcttcttct tttacaattc taatagtttt attaaagcca aagtatatat
    25141 ctccatattc tttcgtatat gatttattgg tactctttca tctactccat gaccaccagt
    25201 tttatacgct aagaacttag gtccaaacgc caccatatct ttaaaccaac ttgcatatgt
    25261 gccaccaccc atagcaattg tatatccatt ttcatctgtt acttcttcat aggcttctaa
    25321 taatttttta agtactaaat tactctcatc cacataatgt aagtctttat gagcaataac
    25381 ctctattttc caaccattac aaaaaacctt tttgaatcta tctattatat tgtttaaaac
    25441 tatattttta ccatacctta tatctaactc acatacgatt ttttcctcat ttacttttaa
    25501 tattcctaaa tttaaggtag tgtttttgaa tacctcatca tattgattaa tccctaatgc
    25561 atctccataa taatcactac aaaggtattt tgaaactaat tcgatatctt ctctatgctg
    25621 aaaatccata ttatcctcaa ctatctttat taccatttta gatatagcat tttctccctt
    25681 ttcaggatta cttgcatgta cagctactcc tttagtagtt aactctgaaa taattccatt
    25741 aataattttt gcagtacaat gagatggaac aacattttct ttagttcctc cccttactat
    25801 tatgtaaggt ttacttttgt caattttaat ttctttttct atccttatat gaacccttcc
    25861 tttttctcca ttaaccactg gatacatagc atctggagta aatcccatac ttggaatttc
    25921 ttcaccttta tctaagtaat atttgataca tttcatacct gtctcctcat ttgtaccaaa
    25981 aattaatctt attcttttat taattgtagg atacatatcc tctatgtttt tcaatacatg
    26041 tataagcata gatacagcac ccttattatc tattacacct cttccataaa taatattgtc
    26101 aattactgct cccgaaaatg ggtctacact ccacccctct cctggtggaa ctatatctaa
    26161 atgcattgga atccctatta attcctctcc ctctccaatt tctgcatatc caatataatt
    26221 atcaatattt ttaacactaa aacctaaact agcacagtaa tctaaagttt tatctaaaga
    26281 ttttttaggt cctataccaa aaggacattg tgaaataggt tcaccttgtt gtgaatcaat
    26341 ttttatcaat tcttttagaa attctatggt tctatttaaa ctattatcta cacttctgct
    26401 tatatccata aatcaaccta ctttctatct ttttaaagcc tgtccttaaa gaacaggctt
    26461 ttagcattaa aaattatttt tttgtaaata ctaattcaca aacttcatca tcatgagcac
    26521 atttttgagc aaaatctaat ttaacacctt gtgcgcagtc aactcttcca taatccccat
    26581 aacaagctaa tctacaaatt tcttttcttt cttctttagt taatccatat tctttccaag
    26641 cagcatctaa tggacagtga tggaatttta aaacgccatt ctcatctgta ttttctacta
    26701 attccatttc aaacactttt tgtcctttac tgttatataa catttctgcc atttttcctg
    26761 gagtatctgc tacgttatat ttttgacctc tcattttacc aaatccatat attgcttctt
    26821 tacatatatc atctggatta gctcctaatt tttcagcttc tttcataaga agatagaacc
    26881 atactgctct ttctcctgtt gctcctctaa ttccttctaa atattccttt tctgtataca
    26941 ttttttctga catttctttc tcctcctaaa attaaattct atattttaat cactgtgaat
    27001 tagaatattc caatgaatga ccctaccaat gctaatacaa ctaaaattac taataactta
    27061 gttattgtcc acttcttgta tttcattccc caatatacga agaatacaac accaagtggt
    27121 aataaacctg gagcaatcat atttaatgta tcttgaacaa caattgcttt accaccaata
    27181 tcaaatgata gcggagttga aagcttaact gtagttgcag ataatgctcc catcataaac
    27241 attcctagaa ttgaagcacc atcaattatc ttattgacaa taccacctga tagaattttc
    27301 ttaattgaat ctctacctaa agaatatcct aaatgaaata agtaataacc ttcgcaaaat
    27361 agtaatatac taaacattat tgggaaaaat gcacctataa cacttccttc tgctccaaat
    27421 gaagcaccta aagctaagaa tattgtttga aatgtaccaa aatctaaagt atctccaatt
    27481 ccagccaaag gtcccataag accattctta acacctgaaa taacttctcc tgggattttt
    27541 ccttcagtag ctttctcttc ttccatagct aaaactgtac cgtgaattaa tcctccccat
    27601 atagcttgag tattaaaaaa ttgtaagtgt ctctttaacg catctactaa atcttctttt
    27661 ctcttatata acttttctaa agccggagtg aaacttgcac aaactgctaa tgcttgcatt
    27721 ctttcaaaag agttggataa ttctgctgtc caccaccatc ttagatatgt ttttgttaca
    27781 tctttctttg taagtactct tgtcttatta acttcagttg gaccttgtcc atttttaact
    27841 tctttatttt ttatttcttg cattatactt cacctaccct tttgtcttct ttcataaagg
    27901 taattaaaag agctatacaa acaccaaata ttgcagctgc agtaattgat atttcaaaat
    27961 attgaaccat aaaaaatcct ataataaaca ttggtaaaaa tttattttta cctatagtaa
    28021 atattgttgt tgcaaaacct aatgcaggta atataccgcc cattactgtt aatccattca
    28081 ttaaccattg tggtataaca tctaataatg attgaactaa atctgctcca aaaaagttac
    28141 atacaaaaac tattggaaac cttaaaacaa acccaaatat taaagaataa agtgttgcac
    28201 atctccagat gccttttgta ttaccttctt cagcatactt atctgcctta tgaaccaata
    28261 cagcattacc agttcttctt aagttattaa ctaatactcc tataacacct aaaggtaccg
    28321 caatagatac tgcaacttct gcattaacac cagtttgaag tgctactggt attgcaataa
    28381 gagcagctag acatttatct gatggaatat ttccccctgc tgcgaccatt cctagataaa
    28441 ccatttctat acttgcacca acaatcatac cagttgttac atcaccccaa agtaatccaa
    28501 ggctaaaacc tataaataaa ggagacttta gtgttgagaa aagggtatac cctgcaagac
    28561 ctgctgcaaa ccaataccat aatcctgtta caattgccaa catcaaaaca gattccattt
    28621 ataattcctc ctaatttata ttttttattt aaatttcttt aacgcatttt catatgtcat
    28681 agatgattcc tctggtataa cttgtaggac tatttcaacc ccattttcat taagttcatt
    28741 aagttgttct acatcctcat ttcctaatga aacagctgta aacaccattt tctttcctgc
    28801 ttcatttgga atacctccta attgaatctt ttcatattta agtccagctt tataagcctt
    28861 atttgccata tcaacatttt taaatagaat aaatatattt ttatctccta aagtgttgtt
    28921 ttggaatgct tgtcccgcat cttctgctgt taaaataact acttctactc ctgatggtgc
    28981 tgccatttta tatatgtcag ccataaattc atcttgacct aagaagtcat caactattat
    29041 tattttttga gcttgagcga tttttaccca ttttgttata acttgcccat gaattaatct
    29101 gtggtctact cttactaatg ttatttttgc cattatattc acctcataat ttatattttt
    29161 ttaaattctt taattaaatc cacacaaagg ttattatttt ttttgacgat tctttctggt
    29221 aatgtatgta atttatcttc tttgcttaat tcttcatcta cgattaaaat tgtctgtaag
    29281 ctaagtccat ttattgcatc tattcctctt cttatagcaa cagctattgc aacacttgat
    29341 gtagatcctc catataaatc tgatattata attttcacat cttctttatc tactacttct
    29401 tcaacctctt tcataaatac agaaacatct ttttcagaac ttagtgataa aacttcatat
    29461 tgatttgaca atccaaagtt tttatttgtt tcttctacta agacttttcc ccaagttcca
    29521 tggcacagta tgattacctt atatttattc attgctaaat aaactctcct ttatagcgat
    29581 taatattttg gtttaattct acttcttctt catcaggtac catttgaatt gatacattaa
    29641 tattcttttt aataaattca tctattaaaa gaaactcttt tttattaatg tatacatttt
    29701 gagatatttt cttttttcct attcctgtag gtattcttcc aacaataagt tttttgatat
    29761 taatcccttc ttctatcatt ctatttgcag tatctaaatt tttaattaat acaaaaacgt
    29821 tatcatcagc ttgattatta taaaaatatc tccttgattc acttacagtt aatattgata
    29881 aatcaatatt ctttggtgct gccattttta tcaaaccttt agcaataaca tcattggttg
    29941 tttcatcatc tactactact atctttttta cacctagatg cttaacccat ttatatataa
    30001 cttgaccatg tattaatcta tcatcacatc tgcaatattt tactaaagac atttttaatc
    30061 aaactccttt ttctattaca ttgagctaag aactttgtta atattgttta taccagtttg
    30121 tcctgcttca atacatgctt ctgctaactc ttctaaactt tttccctctc tattaattaa
    30181 agcttcaagt agcattggaa gatttactcc agtaagtgca tgaaacttgc cacctttttt
    30241 aaggtttaaa cttgcaacat tacttggcga acctcctaat aggtcagcta atactaaaac
    30301 tccgtcacct tcatctaatt catttaactt ttctacaaaa tttttattta agtcttcaat
    30361 attatcattc ctatttagtt taattgctgc tgttctttct gctggtcctg caataagttc
    30421 acagcttttt ataatttctt cactaaaact cccatgagtc ataactatta ttcctatcac
    30481 caatttcacc tcacttttct tgtcactttt tatataagca attgccgtgc caacttatgt
    30541 gtatcaataa caaatggcta ttttacagga tttaatcaaa actttttatt caattttttt
    30601 taaaaactta ttatttcgat atgtatcaaa agattttttc aacctgtatc aaatctgtat
    30661 caaaaaaagt aaaaaaaaga tagccttttg gctattttta aattttgtat caacttttga
    30721 atttatctgt atcatattgt gattcaaata tatctaatat atttgcatat tccatatctg
    30781 aaataattat atcgaatgtc tcttctacta gcttaaaact ttcttttata actaaatata
    30841 attctttatt tctactaatt ctttcttcat atgatttata aactaaagac tcttttatta
    30901 ttactctttc aatcatacat gaacaatgaa atataaactt tactaaaagt tcatcttgaa
    30961 ttactaaaga atagtgttca ctaattctat taattacttc ttttaatata aaataagcct
    31021 tttccccatt taaaaaagtc aaagttttac taatattatc aattagtaat ctatcaaaat
    31081 atctaccacc attatctttt tcagcatatg taacttccat atctccataa tgtttcttta
    31141 tagattctat aatattaaaa tataatttct ctaatgtcat ttctggagtt agagcctttc
    31201 tagttgcttc tattacaata ggtgtactta ccatatctat tgcttttact tcttttcctg
    31261 tagcatcacg aataacttta gcaaatgtta aaatagaccc catatcagtt aaaattaaaa
    31321 ttccctttcc tttatcaatt ttattggcta tttctacagc ttgtactaaa atatcctgaa
    31381 ctctatcttc taatcccata ttaattgcca ctgcatggtt acaatccagt aaagtattgg
    31441 ctacattcac catgctagat gctgtagatt caccatgcat tatgactaat attgctatac
    31501 tctcctcatt taatcccaca tacgataaat aaagaaatgt tgctaaaaaa attgcttcat
    31561 cttctggaaa ctctactcca tacattaatg acatgttaga taatatttct tttgctatgt
    31621 tatattcata tgctctttcc ttcataattt catctttatt aggatgcttt actatatttc
    31681 caatctttat tctttcaatt aaattctgaa tatgtaaagc tatagctttt attaatttat
    31741 ctaatccttc tcttttgctc catttatcat gcttttgtaa aatatatttt acagtagttg
    31801 caattgaatc attaacaatg ttgttataag ctgtttgatt actactatta tatataaaag
    31861 tattcattaa attataggaa tacttctgta tgtctccatc tataacactt ctaatttgtg
    31921 actctttaat accttcttgt tgaagtttat tccaagtttc ttttatcatt ccataaaaat
    31981 ctaaatcata ttttttattt tctattaata aattttcact ttcaaaatcc ttttcttctg
    32041 gtaaaaaaat aatatcatct tttccaataa aactgaaatt ttgtacaaac tcctcttttc
    32101 tattatttcc atataatgat tctctaatat tatttggtag aagagagagc cttacatata
    32161 cacattccct tttataggtc atataatcta aaaaagctct tgcacaaatt aattgtatat
    32221 cgctttttaa ttggcctatg tttcccttac acttatataa aataaatgcc ttaataactt
    32281 cttttgaaac ctttaactta acaccaatcc taacactctc ttctttaaaa aaataacata
    32341 taagcttcat tctctcttga aagcctcttt cctctaaaga cggaatcttt atagttacag
    32401 gtattcttct taaaaacgtt tccaacattg ctgtttctgg gtcttctgta gtggctgcaa
    32461 ttatcataac tctacactcg tgtaccttat tagcctctcc taaccttcta tatatccctt
    32521 tatccataag cagaaatagc atttcttgtc cctctgcaga taatctatga acttcatcta
    32581 aaaacaatac tccattatta gcttcatgta caataccata cttatcttta tcagctccag
    32641 taaatgctcc ttttacatat ccaaaaagct gcgctaataa taattgctga ttatcagaat
    32701 aatcagcaca gttaaatatg ataaatggtg cattatcact atcttctttt atagttaaac
    32761 tatacttata catatattct gcaaatatag atttaccaac tcctgtaggt cctattatta
    32821 atgtactcaa ccccttaggt ggatatatta ctgctgcttt agcctgttct atttgggatc
    32881 ttaaacttcc atcacatcct actaaattaa aaatattgtt ctcttttttt atactctcta
    32941 aaatatactc atctttgata gaatcatttt cactatattc gtttatagag ttaatattat
    33001 caaatatccc tttatttagt ttctttccta aaatactctc aatactttct ttatataagt
    33061 actgaacagg cttacccttt atctttataa tgatactttc ttttattaat tgatttaatt
    33121 ccttactagc attacttcta tttataccta cttcagtagc tatatattct gcatcaaatc
    33181 caaatctaat gccattatta aagttcaagt gttcttctgt taaccttttc aagcaaatta
    33241 aaactttttc tttccttgat agcttctttt gtgtcatagt taacctcccc tataagcagt
    33301 aatactgtta aacatttatt attaagctta attctacaat attttaatat ttttgtctaa
    33361 ttatgtaact attgattttc tttcctattc gttttataat ataaattacg ttaccctcat
    33421 cttttataga ggaggaattt atatgaattt tttatcagat ttacacaccc actctatagt
    33481 cagtggtcat ggctatagca ctttactaga aaatattaat tattgtaaag aaaatggaat
    33541 taagatacta ggtacatctg aacatggtcc taagatgcct ggttctcccc acagatggta
    33601 ctttcacaac attcaaaata tcccaagaat cataaataac attataattt taagaggctg
    33661 tgaagcaaat atactagata ttaaaggaaa catagaccta gagccttttg taattcctcg
    33721 gttagattat cttatcttgt catttcacga agctgtgttt tctccaaata cattagagaa
    33781 taatactaaa gctttaataa atgcaataaa taagcatgat aatattgaaa tattaggaca
    33841 ccttggaaac ccaaactacc caatcgacta tgaattaatc attaaattag ctatagaaaa
    33901 gaatatctta atagaaataa ataattgttc tattaaaggc gtgtcaagaa atggtagctc
    33961 ggataactgt aagtatattg ctacactttg caaaaaatat ggtgctaaaa tcatactaac
    34021 ttcagatgct cacatttgtt ttgacatagg taactatgag tattctgaaa atatcttaaa
    34081 ggaaattaat tttccagatg aattaataat gaattatcct aaaaaactta ttaatcattt
    34141 tcatcaaaaa ggtaaattac tagatgttga ttatacaaat atctaagtaa taatacatgc
    34201 ttactttaac tcccataaaa attttaatac tatttatatt atatgaaata aagaaattat
    34261 aataaagaag ctatttaata aagcttaatt acttttatga acttgatgga ttgatatggt
    34321 ctatgatagc aatagaaatt ataacatttt taataagctt agttttatat accttatagt
    34381 ataaagctaa aaaaaagaat catctaaaat aaagtaaatc ttatataagg tttactttat
    34441 ttttatttgt aataatcatc aatacaaatt attttattat atgtaattat ttatgtctta
    34501 accaatttta tcgaaaataa cagtcttctc ttttaaagag atttttccta cttgatatcc
    34561 atattcattt aattcctttt tatatttcaa aaacgaatgg tctatctcta tcccagcaat
    34621 atcttttatt tcttcaaaag ttaatttaaa cgattgacta ttgtttttct taacatattc
    34681 ccataaagaa ctatatttac tcatcttata tcactccttt taaaatcata tcttatctat
    34741 taatttatat tctatcatta ttaatgtata aagtcatgct acttattatt tatatataaa
    34801 aatatccaaa taataagtag caatttttta tagtcataat atttttttca gattaaataa
    34861 aaatcaatta tagttaaaat attttttaaa agaaatctat cccattataa agtaaatttt
    34921 aattatctta tttctagtat gtaattattc aaaatagtat atcattattg aaatacacat
    34981 ctaataacta aaaattttta catattcatt agttaaaaat ctttttattg catttaaatt
    35041 aaatctatca atatttcagt aataacgttt tcttaatttt cgctatggat gtcgattcaa
    35101 ttataattaa agctctacat caatcttttt accactcatt gaacaacaac taacttttgc
    35161 cttatcaata gagaatattt caaacttacc atctcctaca gagtacatct gacctaaact
    35221 tggcattatt tcaagtgcct tagcttgtgt ttcttttgat gtaacaaata ctgcttcacc
    35281 taaaatacgt agagtattaa ggttttggtc tatacaacaa agttcaacct ttggattaaa
    35341 aataagttgc ttaaacatat ccttttgatt agatgtgcaa aatgtaagtt taccattgta
    35401 ttccataaca aatcctaaag gacgcacatg tgcttgattg ttctcatcaa ctgttgctaa
    35461 ataataaact cctgccttgt tcaaaaattc taatgctttc ataattctta cacccctttt
    35521 aaatacttgt attaaggatt atcctttgat ataattttaa tataaaatac agaaaaaaca
    35581 agtatgcagt tttttctgat aaagtataaa aaagatacta ctataactaa ggagtaatta
    35641 aaatgagtat aaatactgaa aaaaatataa ctaaaaacgt tgaagaatta acctgtccaa
    35701 tccgttatgc attagacatt gtcggtggta agtggaaatt acctattata tgtatgttag
    35761 cagttgaaaa tccaattaga tatagtagca taaaaagaaa attggatggc attacaaata
    35821 ctatgctagc tcaatcatta aaagatttag agtctactgg tattgttcat cgtaaacaat
    35881 ataatgaaat tcctccaaaa gttgaatata cattaacaag taaaggtaaa agtattgtgc
    35941 ctattttaca acaatttgct aattggggtg ctactaatat gcaagaaaaa aacacatgtg
    36001 gacttagttg caaagaatgt agaaagataa agtaaattta aatttactaa attattcata
    36061 ttatagacta tatattaatt tatctgattg aatataaaaa caggatgact tatatattca
    36121 tcctgttcta tatgttaagc tctaaattta attagttcaa gcatatcgtt taataccaat
    36181 aaactatcta cttgaatcat tagccattta cttccattaa aaaagtttac ctcattatat
    36241 atttttttga tataatcaca acaagtatta ataaataaat caacctctac tctattgctt
    36301 tcacttacaa taaccaaagc tttaaaataa ccttcttgtg gatataaagt acatagtgat
    36361 ttacctcttt ttttatattt tacattccaa cctctttgca ttgaacattt actgtattca
    36421 agcttaggtt ctacattata agtagaaacc aaagttttat ttaacttgtc ccataatgga
    36481 ttattaataa attcattaat ttgctcaaat gtaggtttag tatcttgaaa aaacgcatct
    36541 tgccaattca tattcatcat cctttctatt gttcaatagg aaccggaaca atccaatgtt
    36601 ccagatatgc tgcttcaggt gtagtggggt aatacatctc aattgcaaaa tcagtagttg
    36661 ttaaattatg tttcttcatc catctttcca taaatttatc tgctttaaaa acagctgaat
    36721 taactaactc attaaagttt tctgcctcaa atccacatac taaatattct ttagctggca
    36781 actcaaaagt actatatcct tctactgatg tacctgactc tacctctaca cctgccatat
    36841 acatacaatt tccttctttt gcatttccca tataaagagc agcaaattca tttccacctg
    36901 gaatttgatt tggtatatta tgtctttgac ttccaagttt catccataat tcctctacta
    36961 ttgcaattcc agttgtttca ccgcccacca actggcaaat aggtacttct atttctattc
    37021 caacaaatgt ccttggatta ctcaatgtct tacgattgac ttcaatcact atatcatctg
    37081 caatcagtgg aacaccttca tcaaccatag cataatttaa aattaattct ggcttaataa
    37141 aatgattgag ttttactgga tttgctctat atttttctgg agttaatcca tatgcttttt
    37201 taaaggaacg tgtaaatgtc tcatgactag caaatccaaa atttaaagct acatcaagta
    37261 tacgattctt atgttctgct aagtattcag aagctcttgc aagacgacga agctttatat
    37321 actccattac agtcttattt accaatcttt taaatagtct ttgatagtaa aatggtgata
    37381 aatttgcttt atttgctaat tcattaattg atatttcttc tgataaattt gcttctatta
    37441 aatccaatgt aatttgaata gactcccatg catgcatact ataactcctc ctgatatttt
    37501 tgttactctt atcctttata gtatcaaaac tagaaaaaat gttcttgata gatagtgccc
    37561 tttttaattt tcttatatga taatgctaaa tctcattgct ttattataaa cataaaatat
    37621 ataaaaataa aatatagcaa atctttaggt aagatttgct atattatata ttttattaaa
    37681 ctatttttaa atactccatt tatttcctta agaaagaact ctttcatatc atctaattgt
    37741 tctttatcat acacgtactt accatatcca aattgaccgt atttaaactt tctatcttca
    37801 ttttccattg gcaatagtgt atctggataa atctctagta ttctattttt tgctttagtt
    37861 gtatatctat gagatataac ttcaaatata atttttttat caaaatcctt tggtaaagct
    37921 tcttttatac ttataatcag atttttatac tcttctttcc aaccttcata taaaaacaca
    37981 ggtgctatta tgaaaccaat ctgataacca gccctagcaa gttttacagc tgactctatt
    38041 cttttatttg cagaggctgt ataatgctca tgttcattta taattctagg agtattgata
    38101 ctaaatcgta tttctgtatg attattatgt tcagcatcca ataagctatc cacatcactg
    38161 tatttagtaa caaatctaaa tcttcctttt tcctctcttc caaaaaactc tattgttttc
    38221 ttcaaagaat tagtatatgg ctctactgga actgggtctg atgtagctgc cccttcaaat
    38281 atggttacct gtggctttct atcttcaata tatttttttg tctgttcaag tatttcatct
    38341 acatttacaa acacccttat aaatggttta tcacctaatt gtgtgttcaa ataacaatac
    38401 tcacatcttc ccatacatcc actgacaagt ggtagttgat aattagcaga aggtttacat
    38461 gtttgaaact tcagactttt tctaatccca actaccatag tctgcttccc acttctatat
    38521 tgttcatata gattttcacc tggaatatgt tctttaatcc tatttgatga tatattaatt
    38581 atctctacat ctttattatc tctaaattta ttgtatattt ttttacccac atcagtgtct
    38641 aaagttcctt tttcgaatat tattcttttg ggattaaaca tttatttcac ctctacttaa
    38701 agtttttaaa tcgaagaatt ttataaaata ttacttaatt aatcttccct tttttaaact
    38761 cctttattta ttagaaagta aaataaaagc t
//
LOCUS       DAYAOO010000034        38063 bp    DNA     linear   BCT 12-OCT-2024
DEFINITION  TPA_asm: Clostridioides difficile isolate ST8-SSI-h139-18
            SAMN40601845-rid21577343.denovo.034, whole genome shotgun sequence.
ACCESSION   DAYAOO010000034 DAYAOO010000000
VERSION     DAYAOO010000034.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN40601845
            Sequence Read Archive: SRR28438827
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 38063)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 38063)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-MAY-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-MAY-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002157583.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002157583.1
            Genome Coverage       :: 163x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/11/2024 16:19:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 4,038
            CDSs (total)                      :: 3,963
            Genes (coding)                    :: 3,930
            CDSs (with protein)               :: 3,930
            Genes (RNA)                       :: 75
            rRNAs                             :: 6, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 60
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 33
            CDSs (without protein)            :: 33
            Pseudo Genes (ambiguous residues) :: 0 of 33
            Pseudo Genes (frameshifted)       :: 7 of 33
            Pseudo Genes (incomplete)         :: 25 of 33
            Pseudo Genes (internal stop)      :: 11 of 33
            Pseudo Genes (multiple problems)  :: 8 of 33
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..38063
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN40601845-rid21577343.denovo.034"
                     /isolate="ST8-SSI-h139-18"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Denmark"
                     /collection_date="2018"
                     /collected_by="Statens Serum Institute"
     gene            31..159
                     /locus_tag="ACGI5H_001913"
     CDS             31..159
                     /locus_tag="ACGI5H_001913"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016056405.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9697616.1"
                     /translation="MGRLERSKKKRENKFNIVKKVFSFILLLLNIILAVLRILKEL"
     gene            398..580
                     /locus_tag="ACGI5H_001914"
     CDS             398..580
                     /locus_tag="ACGI5H_001914"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894333.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AbrB/MazE/SpoVT family DNA-binding
                     domain-containing protein"
                     /protein_id="HFG9697617.1"
                     /translation="MEKEKRDLKFNFHKGGSGSFTPRMSVPKKWADEMGITRENPNVT
                     ATFEGDRIIIEKAKNE"
     gene            869..1678
                     /locus_tag="ACGI5H_001915"
     CDS             869..1678
                     /locus_tag="ACGI5H_001915"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894335.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ParA family protein"
                     /protein_id="HFG9697618.1"
                     /translation="MANTKLLTYFNIKGGIYKTTTSIMTAYELAKDKDKKILLWDLDV
                     QANLTQYVYEINHNDNTTLDILKGISANDAIVKSPNEKYINVDLIPSDIQMARFEQEL
                     SPLPAREKFLARWYMQNFNTLSEYDYIICDLSPRYDLTAKNVLFLADSIIIPIQDKNI
                     SSLRGAELFKQLWDVDRTYFDKEDNIKSTVLVGFEKKKTQISDTFDSYLEGFNDMRDI
                     MLDTYIRKNEFIEKALLKKLSLTDYTKITKEHFSRQEFANMLEELKVKGVL"
     gene            1679..2014
                     /locus_tag="ACGI5H_001916"
     CDS             1679..2014
                     /locus_tag="ACGI5H_001916"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016040102.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9697619.1"
                     /translation="MPKFDEELLSNKEKPVFKKNGTIIQNNSTTTDNKTLNIYNLVNK
                     KSKKVTMSATLDEELVNKLKSFSIDMNSDVSKLLSDVLTQILSDVTIKEENLNIYNER
                     NRRNKTKKK"
     gene            2157..2438
                     /locus_tag="ACGI5H_001917"
     CDS             2157..2438
                     /locus_tag="ACGI5H_001917"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894338.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9697620.1"
                     /translation="MNVYLQIGKELSEKMTKSELNKFSQEVANYLQYAGLDKNMKIKL
                     FQTILEMVARKKITLSSDSEFTEGILQSDEAEMTMNVGFIIEGLSYHNN"
     gene            complement(2781..3221)
                     /locus_tag="ACGI5H_001918"
     CDS             complement(2781..3221)
                     /locus_tag="ACGI5H_001918"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9697621.1"
                     /translation="MDKMDKKEAKKFLKVIDMNIDKIEEEAIKAFKESCLIKETNDIK
                     IYIDIQGKVEAIAIQAYAKLLDDDKEINIFTSRQTGNNLDDMFGEIYYVNDYEEFENW
                     CENKCESLNWDSYKKFNKENFEEIAERNIDDSTSVFFRRITRRH"
     gene            complement(3244..3747)
                     /locus_tag="ACGI5H_001919"
     CDS             complement(3244..3747)
                     /locus_tag="ACGI5H_001919"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009900694.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9697622.1"
                     /translation="MNIDFSTILDLKVNKENVKMIEKEINKINNDIFDISLKDCANGH
                     IGSVKETVGKSLNIETWGHGEINSKIGIRLRFNFYYSKGDKVDIENIENILIYVNSLC
                     SKNVESDLIANVRPKFYKLEEKYSTRIEKCEIRHEFIGINKQEIKEFLEYLTEIEKSE
                     RTVIYKK"
     gene            complement(3824..4657)
                     /locus_tag="ACGI5H_001920"
     CDS             complement(3824..4657)
                     /locus_tag="ACGI5H_001920"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894309.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9697623.1"
                     /translation="MKILFKEAHKMAREIKRKYSNVDYKVQFSLCLSFLNKKGDIKLK
                     ELKGSEKQIIWANDIRTDILNLTNELEKSKIERIKNEDYKIKDMSIEEMTERCKRKFE
                     RIREAISNIENAKFFIDNFRNVLKYNSLNQKAFHINQILKDSQFAKENRNWSFLQGET
                     QASYRLKKVKDYSISYEEAKKIAKEINFNDNWSNEIKENVLEIVEIFDDAVKQATSTE
                     YIEKAKKYIIETLIQKNAQFYRNGFADIKKKQIENYRKIESDERKIEIAYQVFRDGVE
                     C"
     gene            4836..5048
                     /locus_tag="ACGI5H_001921"
     CDS             4836..5048
                     /locus_tag="ACGI5H_001921"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894308.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9697624.1"
                     /translation="MTWKNEIKSILVKENISMNELNNLMNEHNNKNNTVENLRQKINN
                     ETMKYSEILTIANLIGYEVVWKKKEK"
     gene            complement(5094..5933)
                     /locus_tag="ACGI5H_001922"
     CDS             complement(5094..5933)
                     /locus_tag="ACGI5H_001922"
                     /EC_number="3.5.1.28"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018112536.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008745 - N-acetylmuramoyl-L-alanine
                     amidase activity [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase"
                     /protein_id="HFG9697625.1"
                     /translation="MKICITVGHSILKSGACTSANGVVNEYQYNKSLAPVLADTFRKE
                     GHKADVIICPEKQFKTKSEEKSYKIPKVNSGGYDLLIELHLNSSGVGAFGTEVFYYSE
                     KGKEYAQRVVDKLSKPFIRKKGDKEVGNRGVKLDKSLYILNSSKPTAILIESFFCDNK
                     EDYEKAKKLGHEGIAKLIVEGVLNKNINNEGVKQMYKHTIIYDGEVDKIPATVVGWGY
                     NDGKILICDIKDYVPGQTQNLYVVGGGACEKISSMTKENYTMIKGNDRFETLYKALDF
                     IDR"
     gene            complement(5933..6364)
                     /locus_tag="ACGI5H_001923"
     CDS             complement(5933..6364)
                     /locus_tag="ACGI5H_001923"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894433.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phage holin family protein"
                     /protein_id="HFG9697626.1"
                     /translation="MNVTIVFLATNIFIKLVILAIAFDTLLGCLRAIKTHQFNSSFGI
                     NGGIRKVAMIACIFFLAVVDILTKFNFLFMLPQDWVDFLRLNHLGISEFFSILFILYE
                     SVSILKNMYLCGLPVPRKLKDRIGSLLDTMTDELNVKGGSK"
     gene            complement(6433..6615)
                     /locus_tag="ACGI5H_001924"
     CDS             complement(6433..6615)
                     /locus_tag="ACGI5H_001924"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426811.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9697627.1"
                     /translation="MNINNVVVRILAERILNKGLNPLKNRVFELDDVTNTEYRMAVEN
                     YIIEHSGVVEGAEPTV"
     gene            complement(6615..6908)
                     /locus_tag="ACGI5H_001925"
     CDS             complement(6615..6908)
                     /locus_tag="ACGI5H_001925"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889429.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9697628.1"
                     /translation="MDRANRIIYDQTGKILLQTGEATGDILEHDTITELHYIDVEYGS
                     IDYTRNRIIGINIETKEPILEEIPTFISDEEKRIQELENQLLIAENEKVGGIL"
     gene            complement(6925..8607)
                     /locus_tag="ACGI5H_001926"
     CDS             complement(6925..8607)
                     /locus_tag="ACGI5H_001926"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018112542.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine rich domain-containing protein"
                     /protein_id="HFG9697629.1"
                     /translation="MQTEWNFGYNGSPQSVILKPGKYKFECWGSSGGINNSSWYTDAK
                     GGYSKGEITLKKQTTLYVYVGESGFASSSTSNNTKSGFNGGGKGYLNQQIMGTYYSMY
                     GGGATDIRLVGGAWDNEQGLLSRIIVAGGGGGSYYPSTGGAGGGLEGGTGYSSNDRYR
                     PGGTQYQGGIGRVNTENGSFGKGCSVKDSTGEGGGGGWFGGAGMNGVGAGGGGSSYVL
                     TKDSYKPTGYTPTSEYYFDNIVMTPGGNTAGAYGYAQITLLQSLPFLNISSYNSTQAT
                     FKADHTDPTLLTKIEYFIDDVLKETITTDLTAEKTINYTVEDNALHTLKIVVTDSANA
                     TAEKVVSISKGIAPLPAGSTTDEVTSKWMEIKDTFKSGKTSIINTLALKNIEASLNNT
                     LVELSEKIKTSFDSSDASLQDLMNQLTQANNTISQLNSKYKVASGNSVVNYCTNTKGF
                     YFNSDYLFLFPGAIQINGLNFVPNIFFTTFELIDDGYFHKYFVFACRGIFTQDFVITA
                     HYYRLTSYLQDFKVGGEVLKLNERDVYMDNRGIQLPCSRQGSSFKWQAIKFI"
     gene            complement(8625..9506)
                     /locus_tag="ACGI5H_001927"
     CDS             complement(8625..9506)
                     /locus_tag="ACGI5H_001927"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016034202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9697630.1"
                     /translation="MEKSFVFNSVNGDRRYKAEDFREYFASFIGNGVFPNPSSNLQVV
                     DNNNMTITVKKGKGWINGAIYINTDDLVINIDPADGILNRIDRVVLRFDTLNRNIKLA
                     VKKCTFNSSPVATELQRDADAYELGLADIYIRAGAISITQSSITDLRLDKNLCGIVKG
                     TIEEIDTTTLLAQLNTWKDEEISNFNVWRENQENKQEDWYNTTTTNFVSEFNIWFESI
                     KDILDEDAAGNLLNEINKVKEELAKIETTAEKTSYNNATSNLTATNVQGAIDEVVRKI
                     EKFNEVNISIQNDMLPI"
     gene            complement(9506..10585)
                     /locus_tag="ACGI5H_001928"
     CDS             complement(9506..10585)
                     /locus_tag="ACGI5H_001928"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016034201.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="siphovirus ReqiPepy6 Gp37-like family protein"
                     /protein_id="HFG9697631.1"
                     /translation="MQQSIRILDKNINLIAEIDNYEELQIIKKFHKVGEFSLKINANK
                     NHVDKLVKNNIILLGKNYNKVCLILHREFMYTETGEKSDILSVKGVDLKGLLNRRLII
                     PDTGEAFESHEGTQEEIIKAFVNNNCVDPSNPKRVIDNLIISENKNLGSADMWRSSYE
                     NLSDKIQEISEFCGLGWEVVLDANKKKFIFDVITGKDLTINQTENPPVIFRSDFNNIR
                     ARHFTESIINSKNVVYAGAREDATKLVISTGEVEGFERNEVFADVSENTISILQKEGE
                     IKLKEYEELKSFELEIDPKNTFMYEKDYKLGDIVTVQDRKLKVTMDTRIVEVQESYSK
                     NGMKLKITFGSSIPTLFSKIKRMVK"
     gene            complement(10587..11453)
                     /locus_tag="ACGI5H_001929"
     CDS             complement(10587..11453)
                     /locus_tag="ACGI5H_001929"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016034200.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail family protein"
                     /protein_id="HFG9697632.1"
                     /translation="MQKLICRNSKGQEVKLGNSRPFLLEKIENGANTSANISVSNNLG
                     DGVSIDDISIKERLLPISAAIYAKNKEDLELKRAYLTSLFNPKLGEMEFIYTNNALTK
                     RVKGVVQDITFQTPVRLMQKFLIQLLTPSPFWMDEFVLKEEVALWVGDFEFTLEISNE
                     GIEMGHRVSNLICNVVNNGDVECGMKIQFKALATVDNPSLFNVNTREYIKINRTLEAG
                     DLLEITTEFANKRIELVKSNYERINVFNWIDLDSEFLQLEVGDNLFRYDADVGIDNLE
                     MSIYYNPLYLGV"
     gene            complement(11486..16687)
                     /locus_tag="ACGI5H_001930"
     CDS             complement(11486..16687)
                     /locus_tag="ACGI5H_001930"
                     /inference="COORDINATES: protein motif:HMM:TIGR01760.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005198 - structural molecule activity
                     [Evidence IEA];
                     GO_process: GO:0016032 - viral process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail tape measure protein"
                     /protein_id="HFG9697633.1"
                     /translation="MAEDVGELVVRVAMENSSFQQGVNNLNRQMKLIRSEFKNSGAGV
                     KNFGTSLDGLKSKQQMLSSTIQQQTKVVEAYKNKLNESKTTLSNTAQKQVELKEKVNQ
                     AKSAYEQSKATLGENAEETKRLKSELDSLEQEYAKNEEKIRSNSAAVDNWSIRVNNAE
                     SRLSEMRSELDDTTERINQQENKWNQLATKMTEIGNKFSSAGKQMQDVGKKMTMSITA
                     PILAVGAAASKLGMDFEASMSNVQGLSGATADEMVQLEKAAREAGASTSKTAKDAADA
                     LGYMALAGWDAKTSMEALMPVLRLSEAGNLDLARTSDLVTDSMSSLGLSVKELPTYLD
                     QVAKTAASSNTNIDALMEAMIVSGGTFKNLNVPLSEANALLGILANRGLKGSEAGNSL
                     NSIMINLTSGAGQAGVAMEKLGLSAFDSNGKFKGMANVLMELKEKTKDMTEEQRTMYL
                     SMIGGKTQISTLQALLSGVGEEYSELEKKVGNSTGALDKMAKTMQNNNKGSITALMSA
                     IEELGLKIYDALKPSIAQAVSWFQNLTNKLNEMKPSTVETIVKIAGLAAALGPVLLIG
                     GKIIGMIGGVVGAFGTFSAAMAVVTTGAAAATPAVGALAAILGALSSPAAVAIAGITA
                     LGISVATVAKDMSKDAIEPISRFGKSVSESTKEAVGAFMDLEEKTTISLNQLMWSGET
                     VSEKMKQSIVSNFTEMSNQIIAKLQESKEQGIQSLQEMFATSKNLSDKEKEELIKNTE
                     EAYSSKEEKIKKSNEKVNQIMTKASQEHRTLTKEESAEINQIKTDMLNTAVDTMSKSE
                     AEQAAIMERMKANHVDLSAKEAAEVVKNSIKKKDESIKAANEEYNERLKIAAQLRTEG
                     GAENEKLADKVVEEATRQKDESINKAKEMHQGVVAEAQKQAENQANKVDWTTGEIKSK
                     WQVLNDTVKGKMQEWDDIAGNWVEGLKEKISIGWANLKENTVLLWDNIKLTVTNKWTE
                     IKESISLKIEEIKQGISEKWESIKLFFQTTWESIKLIFSNAWDAIKQQLEEKFAPFIE
                     KLKLIFDSIKELFNNVWEVIKNVVLGAVLLILDVVTGNFDKLKTDALQIWENIKQGLS
                     NTWESIKEVFNNALAAIGDLLSGMWESMKSTAITIWESITQTLSNIWENIKSTCSTAW
                     EGLKTICSNTWENIKSTLTNAWESMKTAVTTKLGEIKNNIVTTWNNVITFFKTLPAKL
                     KQAAIDMFTRLREGIDSKKQDAVNASQKVGTDVVNKIKEFPSKFLQVGKDFVSGLANG
                     ISGFAYKVVDEAKKLGQKAADAVRKVLGIHSPSRVMAEIGKFVDEGLAQGIANNSDSV
                     KKATEKITKIIEEETKKATKACEEDIKLFNKQIDELSKQEKAALKKVKGDAKDALKEE
                     YAAKKEKIKEAIALRKEQKEKEVEQLKEIANSAKEQLNKELQDRQEFVKKVDDLTKAI
                     VDALKEKYKQEYEAQQASIKKELDALDKWKEESIDRINSVYDAKIKAIDNELEAFEKA
                     EKEKDRLEQDKEELNKIEEIKTAIKFEHDDTNKEQLQKELEKVLAERKKRIEQQEIED
                     KKEALKKRKEELEEKKKDEIENINQIYESEKEYYNKRLEDAKKFYDERIKESKLQAEA
                     EKLIMDKNQKEIVALLNSYSDAYKNAGQTLGEKLLEGFKPAINEIKNLIDSITREINN
                     ARNEALSLNSDIRKGNSAANSNSGRREATYNNNSRTANYNVNVNSTDSNTAREIERTI
                     RSLAFSL"
     gene            complement(16756..16974)
                     /locus_tag="ACGI5H_001931"
     CDS             complement(16756..16974)
                     /locus_tag="ACGI5H_001931"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9697634.1"
                     /translation="MCKYCEVKINTEPFSMYDTVVRGELLTNDSDIDMYIELKNGKHF
                     LTGASYDYLGISSKETIKYCPFCGRKLI"
     gene            complement(16987..17142)
                     /locus_tag="ACGI5H_001932"
     CDS             complement(16987..17142)
                     /locus_tag="ACGI5H_001932"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9697635.1"
                     /translation="MFLFEKNWSMTDIDNMDIFYYLDILVYMKENKKDNNNPNENDVY
                     IDQISWL"
     gene            complement(17226..17513)
                     /locus_tag="ACGI5H_001933"
     CDS             complement(17226..17513)
                     /locus_tag="ACGI5H_001933"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9697636.1"
                     /translation="MEIKLTINEEEKIFKAPPIALRKLDKVFTLTDKIEDGLNSTELF
                     RELLDFTVDIYGEQFSKDELLDGFYPAGDFINKALEDLSKVSGGFEEKVKN"
     gene            complement(17528..18124)
                     /locus_tag="ACGI5H_001934"
     CDS             complement(17528..18124)
                     /locus_tag="ACGI5H_001934"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016034195.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005198 - structural molecule activity
                     [Evidence IEA];
                     GO_process: GO:0019068 - virion assembly [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="major tail protein"
                     /protein_id="HFG9697637.1"
                     /translation="MAIIGLRNYRIVKLLTDTEETLEYDTKITRLTGAKSVKISPKVD
                     SAENYGDDQLLETASAMGAIEVEIEVADLTLEERALILGYQYKDGVLIEDKNFAPPNL
                     AFGFESPKSQNGSRMVWLTKGVCEPFEEEAKTKEDKIEFQSQKIKLKFMPRIHDGRHK
                     ITADTDVENAPTNAQFFTTDFLKTGVKPTAPAKANLNK"
     gene            complement(18128..18463)
                     /locus_tag="ACGI5H_001935"
     CDS             complement(18128..18463)
                     /locus_tag="ACGI5H_001935"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9697638.1"
                     /translation="MININDLVIETLKPLKIPVSFQRFDGEEKTYITFFSYLEQNRYA
                     DDEVVGTEHYIQIDLFSKNKMSYINKEIERLLKKNNFIKRSIHEIKESDYSYHTIFRF
                     LFFAEKKED"
     gene            complement(18463..18906)
                     /locus_tag="ACGI5H_001936"
     CDS             complement(18463..18906)
                     /locus_tag="ACGI5H_001936"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016034193.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HK97-gp10 family putative phage morphogenesis
                     protein"
                     /protein_id="HFG9697639.1"
                     /translation="MSVEITTEGFDAILSKIESMGKTGDKLLNEAVKAGGNVILQDAL
                     PRVSKRSGKLKDGLKVSGVKKKGGTKYVLVGITKEDNSEIFYGKFLEFGASAHKIPIK
                     KGKKKGRVVNHPGTSSKPFLAPAYESKKDEAKNVMKEILKRGLGL"
     gene            complement(18907..19233)
                     /locus_tag="ACGI5H_001937"
     CDS             complement(18907..19233)
                     /locus_tag="ACGI5H_001937"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016034192.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9697640.1"
                     /translation="MHSKIVTILKKLNLGIGFQEYDNFSNDEEYIIFFIENEYDANFS
                     DNENKSIVYSIKIEYWYKSLKNINKYISIKDIFKKENFIFLNSSDFIENEYYCKELKF
                     KYEEVV"
     gene            complement(19253..19903)
                     /locus_tag="ACGI5H_001938"
     CDS             complement(19253..19903)
                     /locus_tag="ACGI5H_001938"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016034191.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="head-tail adaptor protein"
                     /protein_id="HFG9697641.1"
                     /translation="MKKIKFNNFNDGIVEFGEYKESYDIEGNALDEKEFIVSGKLFYS
                     NEYIREQDKLKFDDTGLKVSIKLKVPYMRLIKTSDVIKLNNEFYSIVKLDISNDKTSV
                     YLYLTELVDVLDKHISIFIKERKNVLEDVTIKFYKKIWACVEDLNSKELIENNSIKTS
                     TNKKFKIRYIEELDLSIKQNAITNFVIKYKDKFYNITQILNLEEENKILEITAESK"
     gene            complement(19906..20193)
                     /locus_tag="ACGI5H_001939"
     CDS             complement(19906..20193)
                     /locus_tag="ACGI5H_001939"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016034190.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9697642.1"
                     /translation="MENENIKSVVEEVKEYLNITWIEEDAKIEKMVVRGIDYFENEIA
                     GIALDFKDNFNRELLFNYCRYVRNNAIEYFEENFSKELLRLQIKSAANEVI"
     gene            complement(20203..21369)
                     /locus_tag="ACGI5H_001940"
     CDS             complement(20203..21369)
                     /locus_tag="ACGI5H_001940"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016034189.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0044423 - virion component [Evidence
                     IEA];
                     GO_function: GO:0005198 - structural molecule activity
                     [Evidence IEA];
                     GO_process: GO:0019068 - virion assembly [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phage major capsid protein"
                     /protein_id="HFG9697643.1"
                     /translation="MAIKNLDEATNVELRADLMEAIKGNDEEKITTAFLRMAEDIQEN
                     LLKEARSIANIESADRAILDKRGMPQLTSEERAYYSKVIEKRGFTNLEITMPRTVFDR
                     VFDDLEQNHPLLSAITFENTTGVTEWIIRKTNAEAAWWGRLDDTIKKELEHGFDKINT
                     EAYKLSAYLPVAKAMLDLGAEWLDRYVRVVLTESISLGLEMGIVAGTGKDQPKGMIKD
                     LKGAVVEGVFPDKTAKPLADFKPITLGKEIMAPLTNNGKRAVPSVIMLVNPVDYWAKI
                     FAATTMLTSNGTYVYGVLPIPGNIIQSVAVPKGKLIAGMAKDYFMGVASSGKIEYSDE
                     YKFLEDERTYLVKQYATGAPKDNDSFLVFDIENLDTTLATEINSNTKTSAARAK"
     gene            complement(21372..22007)
                     /locus_tag="ACGI5H_001941"
     CDS             complement(21372..22007)
                     /locus_tag="ACGI5H_001941"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016034188.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005198 - structural molecule activity
                     [Evidence IEA];
                     GO_function: GO:0008233 - peptidase activity [Evidence
                     IEA];
                     GO_process: GO:0019068 - virion assembly [Evidence IEA];
                     GO_process: GO:0019082 - viral protein processing
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="HK97 family phage prohead protease"
                     /protein_id="HFG9697644.1"
                     /translation="MEMEKRTVSLEIRDSNLESRKISGYAAVFSDDYTKLQDRWGDTF
                     YEKISRGAFLKTLADNTRDKFMLINHDWNKVVGRTNSNLILEEDEHGLRFEVDIPATT
                     DGNDLLENVRLGLIKGCSFGFNIVNSKTRWDDDWTFYRDITEVELFEITATPIPAYND
                     TEINCRSDISIKELRESQKEETKQNDNKDNIEKRNVDLVSAFFNAFNRGGK"
     gene            complement(21964..23151)
                     /locus_tag="ACGI5H_001942"
     CDS             complement(21964..23151)
                     /locus_tag="ACGI5H_001942"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016034187.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0044423 - virion component [Evidence
                     IEA];
                     GO_function: GO:0005198 - structural molecule activity
                     [Evidence IEA];
                     GO_process: GO:0019068 - virion assembly [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phage portal protein"
                     /protein_id="HFG9697645.1"
                     /translation="MNFKNFISNFLFKDKMSGADGEYFKKLEATIFYKEFALKSCISI
                     IANALVLSEFQTFKNGKSIKEKNYYLFNIEPNQNQNATEFWQEVITRLVYDNECLVIQ
                     ENEQLFVAESFSVDKYVFYEDIYKDVTIRNYKLDRSFRESDVLYFKLNVESIKTVIDY
                     LYNDYKDLLSSAMKGYKKNNSEKGVLEIDTNYPQTKEAQERLNDLMSNKFKRYFESDN
                     AVLPLSNGLKYTENTKASSIKDSRDIRAIIDDVMDFVCAAFHVPAGLVKGNVAGVEGI
                     TDNFLNFSVNPVAKLITNELTRKMYGRDNFFEKSYVKVDTQKIANMGLEKISKASDLL
                     FRIGVNSINDNLEMLGREKINESWADEHYVTKNYQSILNPDLKGGANNGNGEKNGVAG
                     NKG"
     gene            complement(23167..24798)
                     /locus_tag="ACGI5H_001943"
     CDS             complement(23167..24798)
                     /locus_tag="ACGI5H_001943"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016034186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004519 - endonuclease activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="terminase TerL endonuclease subunit"
                     /protein_id="HFG9697646.1"
                     /translation="MMILNYKYNKYIDEYFSLADKGEIVLCKEMKLAVKKIKKDLKKP
                     NIYIDHEKVEKAIEYMEKYFYKMYAWEKFVVALVVGCFEGDELLYDEIFIMMGRGNGK
                     NGFISQLANYLQTHLHGVKNYGIDIVAMSEEQAKTSFDDVYNMLSEHPAICKKFFNRT
                     KEVITFKKTNSYLKFRTNNAKSKDGLRPGCIIFDEVHAYENYDNIKVFTSALGKVKNP
                     RIFYITTDGNVRGGVLDDFKEEAKQILNEEIKNSKMLPLIFKLDSIEEMEDVNLLEKA
                     NPSIKYNSDLRTQILKDIDKAKNRPQMMIELLTKRFNLPAEDLATVVAEWDDIVATNE
                     ELPDLKGFSCIGGLDFSSIRDFTSVVLLFKKDKKRYIMHHTFICYKSLEITNFKFDIE
                     LAKQKGLCTIIYDETIKAEYIADWFIEKAEDYNILKICCDSYRAAHVKEEFTNKGLPI
                     EEVRNGSITHAKIAPLVEQIFAERTIKWGDDMMMRWYTNNVYVDTDKKGNKTFLKIEP
                     IKRKTDGFFAFLHALSKDDELMQESTIKFYDCYTY"
     gene            complement(24779..25285)
                     /locus_tag="ACGI5H_001944"
     CDS             complement(24779..25285)
                     /locus_tag="ACGI5H_001944"
                     /inference="COORDINATES: protein motif:HMM:NF016975.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="P27 family phage terminase small subunit"
                     /protein_id="HFG9697647.1"
                     /translation="MDDNEELEIRRDVQNDYVLGMTYKEMSAKYNIPENTLKSWRKRG
                     GWTRNCTPKKGCVKNGLQESGNNLKNSIRKDLLRQIKENNMTEEYFKDLVEDYLKMWD
                     IKNELIEDVKTRGVQVKYKNGQNQWGYKKNDSVSELIKYNAQMLSLLDKLGIKATPKV
                     LGDDDIEL"
     gene            complement(25457..25789)
                     /locus_tag="ACGI5H_001945"
     CDS             complement(25457..25789)
                     /locus_tag="ACGI5H_001945"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016034243.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HNH endonuclease signature motif containing
                     protein"
                     /protein_id="HFG9697648.1"
                     /translation="MSYKHMTLDRLKELILIDRLDIFYRSTDWRKLRKKALERDNNEC
                     QICKEKKKVSKAECVHHIKEIKEYPSEALKLNNLTSLCNLCHNEIHEKILKINQEKKK
                     KFFSEERW"
     gene            complement(25779..26051)
                     /locus_tag="ACGI5H_001946"
     CDS             complement(25779..26051)
                     /locus_tag="ACGI5H_001946"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016034242.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9697649.1"
                     /translation="MNKYGKFKCNNCGKKVNVNNRDLKTKVIDNTTVTYFMCRRCFEK
                     FVVSYEDDYIKHKREEYKKLKDDEVKLLQDMKEYSDGLGELYINEL"
     gene            complement(26224..26772)
                     /locus_tag="ACGI5H_001947"
     CDS             complement(26224..26772)
                     /locus_tag="ACGI5H_001947"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016034241.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="HFG9697650.1"
                     /translation="MNFVEPIRDLEKLESICAYLEETNMRNNVLFSMGIYTGLRVGDI
                     LKLRIKDVHDKRFITLKESKTGKTKPIEVNPILRRILKEYTKDKNQNEFLIKSREQTN
                     KAISRVMAYKIIREVGEMFGIDNLGTHTMRKTFGYHYYKRTHDVVTLQKLFNHSSATI
                     TLRYIGIEQDDLNKAYRNIKYF"
     gene            complement(26953..27414)
                     /locus_tag="ACGI5H_001948"
     CDS             complement(26953..27414)
                     /locus_tag="ACGI5H_001948"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016034240.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9697651.1"
                     /translation="MKIKKEYFDKVENALKMLGDKYRKLRVLKKEIAILKHKENYREV
                     NYEELGFKVQKSVKGIDDMVVTIEDAIYNKETEIEIIERKLEFYNIYLKELSEIEQKI
                     IELVYFYSWDGKMPITKMARELNYDRTSLYNKKAIAINKIALMIYGDEALE"
     gene            complement(27657..27866)
                     /locus_tag="ACGI5H_001949"
     CDS             complement(27657..27866)
                     /locus_tag="ACGI5H_001949"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9697652.1"
                     /translation="MSMCRKCLCGDYLDELVVGECILCGQEFFSIKTPVGKMCPSCSE
                     MFKGNCSQCAKPIGNEKKLFKNKLK"
     gene            complement(27884..28144)
                     /locus_tag="ACGI5H_001950"
     CDS             complement(27884..28144)
                     /locus_tag="ACGI5H_001950"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016056420.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9697653.1"
                     /translation="MNFKMIANIPELTAKEQFEKVLEEVLELKEAIELKDNKKIMEEG
                     LDVIQAIFTLFKVLKIDKEIREGLKLHNKKLRKRKWKLEKIN"
     gene            complement(28162..28437)
                     /locus_tag="ACGI5H_001951"
     CDS             complement(28162..28437)
                     /locus_tag="ACGI5H_001951"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9697654.1"
                     /translation="MGKTTIEEFLTKIKEEIQCTTKESIKDLENILKEIEIGETEVRI
                     LFIDKKNKIGEIVKFTHDEYMKEIIRKMILEGLDAIKKQHEEILEEI"
     gene            complement(28439..28687)
                     /locus_tag="ACGI5H_001952"
     CDS             complement(28439..28687)
                     /locus_tag="ACGI5H_001952"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016034236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9697655.1"
                     /translation="MKEYRIEIEETIFLKHKVIIEVPEEMCILDILEYVENECQDKSE
                     ISEYIEKNGGKQLNFIEGKRRDSDFTVESCRRIKKGEK"
     gene            complement(28739..29413)
                     /locus_tag="ACGI5H_001953"
     CDS             complement(28739..29413)
                     /locus_tag="ACGI5H_001953"
                     /inference="COORDINATES: protein motif:HMM:NF013658.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoadenosine phosphosulfate reductase family
                     protein"
                     /protein_id="HFG9697656.1"
                     /translation="MKYIASFSGGKDSAAMLLLILEKKLTLDEIVFIDTGLEFEEIYN
                     IIDDFEKRINFKITRIKAEKTFEEYFYTVNKQGKRKGQIWGFPYTLGAWCNSRLKLAP
                     ANKYFNSVGEHKRYIGIAFDEPNRYKRLEENCIAPLYEAKMTEKDCLKYLEEKGFYYK
                     IHHRFKRTGCYLCPKQSLESLRTLRRYYPDLWGVCLNWIRIVLFLSKPMELQCMTWKN
                     DLVMKK"
     gene            complement(29410..29559)
                     /locus_tag="ACGI5H_001954"
     CDS             complement(29410..29559)
                     /locus_tag="ACGI5H_001954"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016034235.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9697657.1"
                     /translation="MSNINKKTAKICGWCGTTIYSYTDGKIAYCSKKCKKKREKNLET
                     EGAKK"
     gene            complement(29576..29983)
                     /locus_tag="ACGI5H_001955"
     CDS             complement(29576..29983)
                     /locus_tag="ACGI5H_001955"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420524.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded DNA-binding protein"
                     /protein_id="HFG9697658.1"
                     /translation="MNNVAMIGRLTKDPELKYIPGSGTAVSTFTIAIDRDYIKKDGTK
                     ETDFIPIEVMGKLAEVCANNLTKGRLIGVEGSIRVNSYEKEGEKRTYTKVHANKIKFL
                     DYKKEDNEKEYMFEPKGLDQQGFQAIDDPDIPF"
     gene            complement(30015..30230)
                     /locus_tag="ACGI5H_001956"
     CDS             complement(30015..30230)
                     /locus_tag="ACGI5H_001956"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016034232.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9697659.1"
                     /translation="MNKISVTQALEKFDSLLDNWNDLPNHVYKKEYRGKFYDWIKSLE
                     RKDSLQNYKIVEVLNDERNGEEAPFWN"
     gene            complement(30223..30390)
                     /locus_tag="ACGI5H_001957"
     CDS             complement(30223..30390)
                     /locus_tag="ACGI5H_001957"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016034231.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9697660.1"
                     /translation="MDKFVTCARCERTINVEENNYVKYEEETLNLSFALYFCLGCVDK
                     IIEEQVEGENE"
     gene            complement(30405..30710)
                     /locus_tag="ACGI5H_001958"
     CDS             complement(30405..30710)
                     /locus_tag="ACGI5H_001958"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9697661.1"
                     /translation="MNINKYEKLCEQQELLYEQYKETKEKIKVYEVLEDRRKGIDTMI
                     RNIDSYFGIGELSMEFNIRGSCDVSCVHFSVGEEEKILLKNFFIELKEKNVRKMEEI"
     gene            complement(30740..31105)
                     /locus_tag="ACGI5H_001959"
     CDS             complement(30740..31105)
                     /locus_tag="ACGI5H_001959"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016034230.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9697662.1"
                     /translation="MNIGSYTLVKKQLIEELEEGNKQKEEYLKECEKHIKGLEKSLEN
                     FARDALESEECIIDIENILIEQALELETYNLFIDCILNKNIRKAIAIYNRTKSIRIKN
                     KNINSISNKIEKIKQIISL"
     gene            complement(31102..31266)
                     /locus_tag="ACGI5H_001960"
     CDS             complement(31102..31266)
                     /locus_tag="ACGI5H_001960"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016056414.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9697663.1"
                     /translation="MQKKISEMSILEKADLISKKQKKLQEKYKNLSKGELFSIACNEV
                     KKIEEQEGKF"
     gene            31355..31699
                     /locus_tag="ACGI5H_001961"
     CDS             31355..31699
                     /locus_tag="ACGI5H_001961"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016034228.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2513 domain-containing protein"
                     /protein_id="HFG9697664.1"
                     /translation="MVTNQDCIRDILLFIESNTTPISPVLQFDTILDNLKYDESTIIH
                     HINLIYQNSLVDDVNYGDDTVLEVTQLSLKGYQYLDEIRDSTKWNKIKSSTSSFLNMS
                     LPIAIEYILGKF"
     gene            complement(31742..32023)
                     /locus_tag="ACGI5H_001962"
     CDS             complement(31742..32023)
                     /locus_tag="ACGI5H_001962"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016034227.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9697665.1"
                     /translation="MIKNNVLSYEEKIKVLKEHGYNDSTKEYILKEFGKEHIFYESFL
                     RAIERDDSKKSVLIKKFEKGQHQFSEGFIKTHTISELLKEEERIRKILG"
     gene            complement(32069..32671)
                     /locus_tag="ACGI5H_001963"
     CDS             complement(32069..32671)
                     /locus_tag="ACGI5H_001963"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9697666.1"
                     /translation="MEINSVRELKELVELFGVIKAESNNVVSCNETVNELSNEELIKA
                     NENKFKKPWNDALLYEINALDIIKKHKHSDRKEKAYKTYLGLENADIEEIYKIHYGDK
                     ENSETVASCEEISSAKTDTISCNHDSVSKGKDTSDSECTCFICSKKIENQEDVFKIPF
                     LTRDYLSSAKEIKNIEICEKCLDGNSWSIIRRKQFKKMKK"
     gene            complement(32694..33584)
                     /locus_tag="ACGI5H_001964"
     CDS             complement(32694..33584)
                     /locus_tag="ACGI5H_001964"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016034225.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conserved phage C-terminal domain-containing
                     protein"
                     /protein_id="HFG9697667.1"
                     /translation="MEGGEGLELLKDSRKRDWFWAENSLVDREDLSIYEKMIYIVLIR
                     YSDEESCCFPSYKTISKKAGCSERQVSNVLKSLEEKGLLIRKNRKRKGSNEKESNLYI
                     LLSAKQEVQHTMPNVRNEVLNPTACGAVHVRNEVLSNKTNINKTNLTNNIYSSAEQKE
                     EKTKDKEIYKRIVDYLNKTADKSFKSTTKKTISLIDARLKEGFTEEEFYKVIDNKVLN
                     WLDDDKMNAYLRPETLFGNKFESYLNETPKKALKGNESVKGKTKTNNNKFANFDQTFN
                     KYSEKELDAIIKKSQSVKFK"
     gene            complement(33599..33814)
                     /locus_tag="ACGI5H_001965"
     CDS             complement(33599..33814)
                     /locus_tag="ACGI5H_001965"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016034224.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9697668.1"
                     /translation="MKLLKSKNIKIGEIIRLHDVKFNHDRKCIVTYIDKDEIVLTYYD
                     EEIKEMTCKVLTKEDLIFNDYELKLLS"
     gene            complement(33851..34072)
                     /locus_tag="ACGI5H_001966"
     CDS             complement(33851..34072)
                     /locus_tag="ACGI5H_001966"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="XRE family transcriptional regulator"
                     /protein_id="HFG9697669.1"
                     /translation="MFRNLKAEMARKNITNEKIAKALNLNVSTICAKLNSINRLKYIE
                     AKKIQTIFFPDLSTEYLFEIEEEKSKKYI"
     gene            34244..34588
                     /locus_tag="ACGI5H_001967"
     CDS             34244..34588
                     /locus_tag="ACGI5H_001967"
                     /inference="COORDINATES: protein motif:HMM:NF024835.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HFG9697670.1"
                     /translation="MNIEERLKQLILSKYKSIRAFTKEVNIPYSTVDTMLKRGISGTS
                     ITTVLKICNALNIDADALIDNELKEKELSSKIQTNQFEQKILKMYNALDEHGKDIVFT
                     ILEKEYVRINKL"
     gene            34771..35070
                     /locus_tag="ACGI5H_001968"
     CDS             34771..35070
                     /locus_tag="ACGI5H_001968"
                     /inference="COORDINATES: protein motif:HMM:NF024949.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HFG9697671.1"
                     /translation="MESLLKYHRKKKKLTQRRLSELTGISQSYISRMENKKFKHSPTL
                     TQIILLADILEIDQLILSEFFLEKEREHLKNTKKYNKKAVKTLSRDFLKEYKNKD"
     gene            complement(35098..35724)
                     /locus_tag="ACGI5H_001969"
     CDS             complement(35098..35724)
                     /locus_tag="ACGI5H_001969"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016034220.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9697672.1"
                     /translation="MKKVLLLITVCLLSVGLVACSSTNNKDTGNTTKKEKKANENEVD
                     GIKITVKDVTKEDIKGDINEDGSFNENGEYFSDGIEKKKAADYVYEVVNVEVENKTDK
                     AVKLFQTGWNAVGTDGYEFKDIKVTDKLDNQQVPANYKFDAQVKILVEKNMNVKEIVL
                     KYNLKDYSRLFEAMEYANQGASKSDVEKKFPELYKDNWIELGEIKVEQ"
     gene            complement(36388..37080)
                     /locus_tag="ACGI5H_001970"
     CDS             complement(36388..37080)
                     /locus_tag="ACGI5H_001970"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016034219.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HFG9697673.1"
                     /translation="MSLEEAKELEKNYKLPMPTYCLNEKNYCAKEFGALMLISKGSMR
                     IMHIEKNRYLYQNKFKMEELAKQIGVARTTLERNIKKLNSLDCKVLEIENSRNGIIYR
                     LNYGTSTGYNDNVHKFVTIHHDMLQELISAFNTNAIKVYCLLCYMTTENSFKCMTEKF
                     ICEKIGLCGDSKNNRSKIRKIITVFEVSKYIEVKKENKFEWDEEKNKKVPRIQKLYRL
                     CSFSEWKNARKK"
BASE COUNT        11312 a         6840 c         4235 g        15676 t
ORIGIN      
        1 aaaaaaaaat aaaagaaagg aggaacggga atggggagat tagaaagaag taaaaagaaa
       61 agagaaaaca aatttaacat agttaaaaaa gttttctctt tcatcctatt attacttaac
      121 ataatcctcg cagttctaag aattttaaaa gaactgtaag gataagccta gagggaatag
      181 cccttctctc taggtgactt ctttctaata ttataacaca tttctaaaaa acatgagtga
      241 taaattttat aagatttgca ttgttttagt tttgataact atagtcttaa atatagtatc
      301 tatagtatta aactctagta caagcaacat gctcggttta gtttttagtg ttgtattatt
      361 gcttttcttt gtaatacagc aaaaaaggag ctaatgaatg gaaaaagaaa aaagagattt
      421 aaagtttaac tttcacaaag gtgggagtgg gtcgtttact cctagaatga gtgttcctaa
      481 aaaatgggct gatgaaatgg gcataacaag agaaaaccct aatgttacgg caacattcga
      541 gggcgacagg ataataattg aaaaggctaa gaatgaatga ctttttctat aaaagaaggt
      601 tgcttttttt cttagccttc ttttttttaa attttactat aatataaaaa taatactgta
      661 atattataaa aatattattt tagtattgta tatacaatat tttagtattt ttaatataat
      721 atattggtat tgtaaaagca atatgtaaat attgtattta tattatttga atattgtaat
      781 taacaatatt aatatattgt tgcaatatta taaaaacaat actacaatat tgttataata
      841 ttataaatat aataatgagg tggagaaaat ggctaataca aagctactta cgtactttaa
      901 cataaaagga ggtatctata agacaacaac gtctataatg acagcgtatg aacttgcgaa
      961 agataaagat aaaaaaatac tcttatggga cttagatgta caagcaaatc taacacaata
     1021 tgtttatgaa ataaatcata atgataatac tacattagat attttaaaag ggattagtgc
     1081 taatgatgca atagtcaagt cacctaatga aaagtacatt aatgtagact taattccttc
     1141 tgacatacaa atggctagat ttgaacaaga gctatcacct ttaccagcca gagaaaaatt
     1201 tttagctcgc tggtacatgc aaaactttaa tactttgagt gagtatgatt atattatctg
     1261 tgatttatct ccacgctacg atttgacagc taaaaatgtg cttttcttag cagatagtat
     1321 aattattcca attcaagata aaaacatttc ttctttaaga ggagcagaat tatttaaaca
     1381 actctgggat gttgatagaa cctattttga taaggaggat aatataaaaa gtactgtttt
     1441 ggttggattt gagaagaaga aaactcaaat tagtgatact ttcgattctt atctggaagg
     1501 gtttaacgat atgagagata ttatgttaga tacatatatt agaaaaaacg agtttataga
     1561 gaaggcacta ttgaaaaaac tatctctaac agattataca aaaataacta aagagcattt
     1621 cagcagacaa gagtttgcta atatgttaga agaactaaaa gtgaaaggag tgttgtagat
     1681 gccaaaattc gacgaagaac ttttatctaa taaagaaaaa ccagttttca aaaaaaatgg
     1741 aacaatcata caaaataatt ctacaactac agacaataag acattaaaca tatataatct
     1801 agttaataag aaaagtaaaa aggtaactat gagtgcaacg cttgatgaag aacttgtaaa
     1861 caaattaaaa tctttttcta ttgatatgaa cagcgacgtc agcaaattat taagtgatgt
     1921 actaactcaa attttatctg atgtcactat aaaagaagag aatttaaata tatacaatga
     1981 gagaaataga agaaataaga ctaagaaaaa gtaaataata ttatatttat attgtttaga
     2041 tattacttaa atattgtata tataatattt aagtaatatt ttaatattat tattacaata
     2101 tatcgatatt gtttaaataa tatgttttaa ctataatcta aaaggggttg gaaaagatga
     2161 atgtttattt gcaaattgga aaagagttat ctgaaaaaat gactaaatct gaattaaata
     2221 agttttcgca ggaggtggca aactatctgc aatacgctgg acttgataag aatatgaaaa
     2281 ttaaactatt tcaaacaatt ttggaaatgg tggcaaggaa aaaaataaca ttatcaagcg
     2341 atagcgaatt tacggaagga atattgcaaa gcgacgaagc agaaatgaca atgaacgtag
     2401 gatttataat cgaaggatta agttatcata ataactaaac atttttaaaa aaacagtgta
     2461 tttattgaat acactgtttt tatttccgca tagttaatct aaaattggat attgtatcat
     2521 atggatatag attaaattga tatttaaatc ccttatagtt aatcttaaaa attgttatta
     2581 tattatttct ctataaatta aattgacatt taaatccctt gtagttaata taaaaattct
     2641 tattacaata tcatttctaa ataaattaaa aaatatttta aatccctcgt agttaatctt
     2701 aaaagcgata ctatatacat taataataat actcttctac ttaattttca actatatttt
     2761 gtaattcttg tttacaactt tcaatgcctt ctcgtaattc ttctaaaaaa aactgatgtg
     2821 ctatcgtcta tatttctttc agcaatttct tcaaaatttt ctttattgaa ttttttataa
     2881 ctatcccaat tcaaactttc gcatttattt tcgcaccaat tttcaaattc ttcgtaatca
     2941 tttacgtagt aaatttctcc aaacatatcg tctaagttat ttcctgtttg tcttgatgtg
     3001 aaaatattaa tttctttatc atcatctaaa agtttagcat aagcctggat tgctatcgct
     3061 tcaacttttc cttgtatatc gatataaatt tttatatcat tagtctcttt gattaaacaa
     3121 ctttctttaa aagcttttat agcttcttcc tctattttat ctatattcat atctataacc
     3181 tttaaaaatt ttttagcttc ttttttatcc attttatcca ttttaatttc ctccattttt
     3241 tagttatttt ttatatataa cagttctttc gctcttttca atttctgtaa gatactctaa
     3301 aaattcttta atttcttgct tgtttatgcc tataaattcg tgtctaattt cacatttttc
     3361 aatacgtgta gaatatttct cttctaattt ataaaattta ggtcttacat tggctataag
     3421 gtcactttct acatttttgc tacacaagct atttacatat attaaaatgt tttctatatt
     3481 ttctatgtct actttgtcgc cttttgaata ataaaaatta aatctcaatc ttattcctat
     3541 tttactgtta atttcaccat gaccccacgt ttcaatgttt aaactttttc caactgtttc
     3601 tttaacgctt ccaatgtgac cgttcgcaca atctttaaga cttatatcaa atatatcatt
     3661 gttgatttta ttaatctctt tttctatcat tttaacattc tctttattaa cttttaaatc
     3721 taatattgta ctaaaatcta tattcatgtt ttaaacctcc aattattttt tattttaatt
     3781 atagcattca atggtgaact atatttgtat caagttgaaa cttttaacac tctacgccat
     3841 ctctgaatac ttggtatgca atttctattt ttctttcatc actttctatt tttctatagt
     3901 tttcaatctg cttcttttta atgtctgcaa atccatttct ataaaattgt gcattttttt
     3961 gtattaatgt ttctattatg tattttttag ctttctctat atattctgtg ctagtagctt
     4021 gttttactgc gtcgtcaaat atttcaacta tttcaagtac attttctttt atttcattag
     4081 accaattatc attaaaattt atttctttag ctattttctt agcttcttca tagcttatac
     4141 tataatcttt aactttttta agtctataag atgcttgtgt ctccccttgt aaaaaactcc
     4201 aatttctgtt ctcttttgca aattgagaat cttttaatat ctgatttata tgaaatgctt
     4261 tttgatttaa agaattatac tttaaaacat ttctaaaatt atctataaag aacttagcat
     4321 tctctatatt gcttattgct tctcttattc tttcaaattt tcttttacat ctttctgtca
     4381 tttcttctat actcatgtct ttaattttgt agtcttcatt ttttattctt tctattttac
     4441 ttttttctag ttcgttagtt aaatttaaaa tgtctgttct tatatcatta gcccaaataa
     4501 tttgtttttc tgaccctttt aattctttca attttatatc ccccttttta tttaagaatg
     4561 ataagcaaag actaaattgt actttataat ctacattact atattttctt tttatttctc
     4621 ttgccatttt atgcgcttct ttaaataaaa ttttcattct ttgcttaccc ccttgtttta
     4681 tttgttaatt atattataat ctatatgaat atctaagtca acactttttc aaagtttttt
     4741 ctttgatttc caaaaatata actttgatta gcgtagatta ttcttttact tttaattttt
     4801 ttatgttatt atataaataa gagaggtgcg aaaaaatgac atggaagaat gaaattaaaa
     4861 gtattcttgt aaaagaaaat atcagcatga atgagttaaa taatttaatg aatgaacata
     4921 ataataagaa taatacagtt gaaaatttaa gacaaaaaat aaataatgag actatgaagt
     4981 atagtgaaat cttgactatt gctaatttga taggatatga agttgtttgg aaaaagaaag
     5041 aaaagtagac ataaaaaaag aaggtaacaa ctaactagtt gctaccttct aatctatcta
     5101 tcaataaaat ctaatgcttt gtaaagtgtt tcaaacctat cattaccttt tatcatagta
     5161 taattttctt tagtcataga acttatcttt tcacatgctc caccaccaac aacataaaga
     5221 ttttgtgtct ggccaggtac ataatctttt atatcacata ttaatatttt cccatcatta
     5281 taaccccatc caacaacagt tgcagggatt ttgtcaactt ctccatcata aatgattgta
     5341 tgtttgtaca tctgtttaac tccctcatta tttatatttt tatttaatac accttctaca
     5401 atcaacttag caataccttc atgacctagt ttcttagctt tctcataatc ttctttgtta
     5461 tcgcaaaaga aactttcaat tagtattgca gtaggtttag aactatttaa aatatataaa
     5521 cttttatcta atttaacacc tctattacct acttctttat ctcctttttt tcttatgaaa
     5581 ggtttagata atttatctac taccctttgc gcatattcct tccctttttc actatagtaa
     5641 aatacttctg ttccaaaggc tcctacacca cttgaattta aatgcaactc tataagtaag
     5701 tcatatcctc cactattaac tttaggtatt ttgtaagatt tttcctcact cttagtttta
     5761 aactgctttt cggggcatat tattacatct gccttatgac cttcttttct aaaagtatct
     5821 gctaatactg gtgcaagaga tttattgtat tgatactcgt taactactcc attagcagaa
     5881 gtacatgccc cgctttttaa aatgctgtgt cctactgtta tacatatttt cattatttac
     5941 tacctccttt aacatttaat tcatctgtca tagtatctaa taaactacct attctatctt
     6001 ttaattttct aggtactggt aacccacaca aatacatgtt ttttaatata cttacacttt
     6061 catatagaat aaataaaata gagaaaaatt cagatattcc aagatgattt aatcgcaaaa
     6121 aatcaaccca atcttgtggt aacataaata aaaagttaaa ctttgtaaga atgtcaacta
     6181 ctgctagaaa aaatatacat gctatcattg caacttttct tattcctcca tttattccaa
     6241 aacttgaatt aaactgatgt gtttttattg ctcttaaaca acctagcaat gtatcaaatg
     6301 ctattgctaa tattactaat tttataaata tatttgtcgc taaaaaaact attgttacgt
     6361 tcatatttcc tccttatttt gcattaaaat aagacttaga attatctaag cctatagaaa
     6421 aaggaacatt acctatactg taggttctgc tccttctact actccactat gttctataat
     6481 gtagttttca actgccatcc tgtactctgt gttagtaaca tcatcaagtt caaatactct
     6541 attttttaga ggatttaatc ccttatttaa tattctctct gctaatattc ttactacaac
     6601 attatttata ttcattataa aattcctcct accttttcat tttctgcaat tagtaattga
     6661 ttttctaact cttgtattct cttttcttca tctgaaataa atgttggtat ttcctctaaa
     6721 attggttctt ttgtttctat atttatacct ataattctat ttcttgtata gtctatactt
     6781 ccatactcaa catcaatata atgtaattct gttattgtat catgttctag tatatctcct
     6841 gttgcttccc ctgtctgtag cagtattttg cctgtctggt cgtaaattat tctatttgct
     6901 ctatccattt tatcacctca tttattaaat aaattttata gcttgccatt taaaagaaga
     6961 accttgtctt gaacaaggaa gttgtatacc tctattatcc atataaacat cacgttcatt
     7021 taatttaaga acctcacctc caactttaaa atcttgtaaa tatgatgtta gacgataata
     7081 atgagcagta attacaaaat cttgagtgaa aataccacga caagcaaaaa caaaatattt
     7141 atgaaaataa ccatcatcaa ttaattcaaa agtagtaaaa aatatattag gaacaaaatt
     7201 aagtccgtta atttgaatgg ctccaggaaa taggaacaga tagtcactat taaaataaaa
     7261 tccttttgta ttagtacaat aattaacaac actattgcca ctagcaactt tatatttaga
     7321 atttaactga cttatagtgt tattagcttg tgttaactga ttcatcaaat cctgcaaact
     7381 agcgtccgaa ctatcaaaac ttgtttttat tttctctgac aactctacta gcgtattatt
     7441 taaacttgct tctatattct ttaatgctaa agtgtttata atacttgttt tgccactttt
     7501 gaatgtatct ttaatttcca tccatttgct tgtaacttca tctgttgtag aaccagcagg
     7561 aagaggtgca attcctttgc ttatacttac aactttttct gctgtagcat tagcactgtc
     7621 tgtaacaact attttaagtg tgtgtagtgc attatcttct actgtatagt taattgtttt
     7681 ttctgctgtt aaatctgttg ttatagtttc ttttagtaca tcatctataa aatattctat
     7741 cttagtcaat aaagtagggt cagtgtggtc agctttgaat gttgcttgtg tagaattata
     7801 agatgatata tttaaaaatg gtaatgattg aagtaaagtt atttgtgcgt aaccataagc
     7861 accagcagta tttccacccg gtgtcataac aatattatca aaataatatt cagatgttgg
     7921 tgtgtagcca gtaggcttat aactgtcttt agtcaataca taactacttc cacctccacc
     7981 tgctcctaca ccattcatgc ctgcaccacc aaaccagcca cctccgccgc cttcgccagt
     8041 tgaatcttta acagaacacc cttttccaaa acttccgttt tctgtattta cacgaccaat
     8101 accaccttga tattgagtac caccgggacg gtatctgtca ttagaactat acccagtacc
     8161 tccttctaat cctcctcctg caccaccagt ggaaggataa tatgaacctc cgccaccacc
     8221 tgcgacaatt atacgagata gcaaaccttg ctcattatcc caagcaccac caacaagtct
     8281 tatatcggta gcaccaccac cgtacataga ataataagta cccataatct gttgatttaa
     8341 ataaccttta ccaccgccat taaaaccact tttagtgtta ttactcgtag atgaagaagc
     8401 aaaaccactt tcgccgacgt aaacatataa tgtagtttgt ttttttaatg taatttcacc
     8461 tttagaatat ccgcctttag catcagtata ccaagaagaa ttgttgatac ctccagaaga
     8521 accccagcat tcaaatttat atttgccagg tttcaatata acactttgtg gcgaaccatt
     8581 gtacccaaag ttccattctg tctgcatttt ctcactctcc tctcttatat aggtaacata
     8641 tcattttgta tagatatatt aacctcatta aatttttcta tttttctaac aacttcatct
     8701 attgcccctt gcacattcgt agcagtaaga ttacttgttg cattattata acttgttttc
     8761 tctgctgttg tttctatttt tgctaactct tcttttactt tgtttatttc atttaataag
     8821 tttccagctg catcctcatc caaaatatct tttatacttt caaaccaaat gttaaactct
     8881 gatacaaaat ttgttgttgt agtgttatac caatcttctt gtttattctc ttgattttcc
     8941 cgccaaacat tgaaattact tatttcttca tctttccaag tatttagttg tgcaagtaat
     9001 gttgttgtgt ctatttcttc tatcgtgcct tttacaattc cacacaaatt tttatctaat
     9061 cttaaatctg ttatagaact ttgtgtaata cttattgctc cagctctgat ataaatatca
     9121 gctaatccaa gttcgtacgc atctgcatca cgttgtaatt ctgttgcaac tggggaacta
     9181 ttaaaagtac attttttaac agctaattta atatttctat ttaaagtatc aaatcttaaa
     9241 actactctgt ctattctatt taaaattcca tctgcggggt ctatattaat tactaaatcg
     9301 tctgtgttta tatagatagc tccgttaatc cagcccttgc ctttttttac tgttatagtc
     9361 atattattat tatctacaac ttgcaaattg ctacttggat tagggaatac accattacct
     9421 ataaaactag caaaatattc tctaaagtcc tctgccttgt atctcctatc gccatttaca
     9481 ctattaaata caaaactttt ttccattatt tcaccatcct ttttattttt gaaaataagg
     9541 ttggtatgct gctcccaaac gtaattttta atttcatccc atttttacta tagctttctt
     9601 gtacttctac aattctagta tccattgtta ctttcaattt tctatcttga actgtaacaa
     9661 tatcccctag tttgtagtct ttttcataca taaaagtatt tttagggtct atttctaatt
     9721 caaaactttt taactcttca tattctttta atttaatttc tccttctttt tgtagtatgc
     9781 ttatagtatt ttcacttaca tctgcaaaga cttcgtttct ctcaaaacct tcaacctcac
     9841 cagttgaaat taccagtttt gtcgcgtctt ctcttgctcc agcatacaca acatttttag
     9901 agttaattat actttctgta aagtgtctag ctcttatgtt attaaaatca cttctaaaaa
     9961 taaccggcgg gttttctgtt tgattaatag tcaaatcttt accagtaatt acgtcaaaaa
    10021 taaatttctt tttattagca tccaacacta cctcccaacc aagcccacaa aattctgata
    10081 tttcttgaat tttatcactt aaattttcgt aagaacttcg ccacatatca gcacttccaa
    10141 gatttttgtt ttctgaaatg ataagattat caattacacg ttttggattt gaagggtcta
    10201 cgcagttatt attaacaaaa gcttttataa tttcttcttg tgtcccttcg tgactttcga
    10261 aagcttctcc agtgtcgggt atgatgagcc ttctatttaa caagcctttt aaatccacgc
    10321 ctttaacaga taaaatgtcg cttttttctc ctgtttcggt gtacatgaac tctcgatgaa
    10381 gtatcaaaca aactttatta taatttttac caagtagaat tatattattt ttaactaatt
    10441 tatctacatg atttttatta gcatttattt ttaaactaaa ctctcctact ttgtggaatt
    10501 ttttaataat ctgtaattct tcgtaattat ctatttcagc tattaaattt atatttttat
    10561 ctagtattct tatgctctgc tgcatattac acccccaaat aaagtggatt ataatatata
    10621 gacatttcta aattatcaat tcctacgtct gcgtcatatc taaataaatt gtctccaact
    10681 tcaagttgta aaaattcgct atccaagtca atccaattaa atacatttat tctttcatag
    10741 tttgatttta ctaactctat tcttttattt gcaaattctg ttgttatttc taataagtca
    10801 ccagcttcaa gggttctgtt tatcttaata tattctcttg tgtttacatt aaataggcta
    10861 ggattatcaa ctgttgcaag tgctttaaat tgtattttca tgccacattc aacgtctccg
    10921 ttattcacta cattacaaat taaattactt accctatgac ccatttctat tccttcatta
    10981 cttatttcta aagtaaattc gaagtcacca acccataagg cgacttcttc ttttaaaaca
    11041 aactcatcca tccaaaatgg gcttggagtt aagagctgta taagaaactt ttgcatcaat
    11101 ctaactggtg tttgaaatgt tatgtcttgc acaactcctt tgacacgttt agttaatgcg
    11161 ttatttgtat atataaattc catttctcct aatttaggat taaacaaaga ggttaaatat
    11221 gcacgtttta attctaaatc ttctttattt tttgcataaa tagctgctga aataggaagt
    11281 aatctctctt ttatgcttat atcatctata cttacaccat cacctagatt gttcgagact
    11341 gaaatattag cactagtatt tgctccgttt tctatttttt ctaacaaaaa agggcgtgag
    11401 tttcctaatt taacttcttg ccctttcgag tttctacata ttaatttttg caagtttcac
    11461 accccttttt ttataaacta tttttttata aactaaatgc tagacttctt attgttcttt
    11521 cgatttctct tgctgtgttt gagtctgtac tattaacgtt tacattataa ttcgctgttc
    11581 ttgaattatt attataagtt gcttctcttc ttcccgaatt tgaattagct gctgaatttc
    11641 cttttctaat atcgctattt aaactcaatg cttcatttct agcattattt atttctcttg
    11701 taatactatc aattagattt ttaatttcgt ttatggcagg cttaaatcct tcaagtaatt
    11761 tttcacctag agtttgacct gcatttttat atgcatctga ataactattt aataacgcaa
    11821 ctatttcttt ttgattttta tccattatca atttttcagc ttctgcttga agttttgatt
    11881 cttttattct ttcatcatag aactttttag cgtcttcaag tcttttatta taatattcct
    11941 tttcgctttc atagatttga tttatatttt ctatttcgtc ttttttcttt tcttctaatt
    12001 cttcttttct cttttttaaa gcttcttttt tatcttctat ttcttgttgc tctattcttt
    12061 tttttctttc agctaaaacc ttctctagtt ctttttgcaa ctgttctttg ttagtatcat
    12121 catgttcaaa ctttatagct gttttaattt cttctatttt gtttaattct tctttgtctt
    12181 gttcaagtct atctttttcc ttttcagctt tttcaaaagc ttctaattcg ttgtcaatag
    12241 ctttaatttt cgcatcatag acactattaa ttctatctat actttcttcc ttccatttat
    12301 ctagtgcgtc taactctttt tttatactcg cttgctgtgc ttcgtattct tgtttgtatt
    12361 tttctttcag cgcatcaact attgcttttg ttaagtcatc aacttttttt acaaactctt
    12421 gtctgtcttg taactcttta ttcaactgtt ctttagctga atttgctatc tcttttagct
    12481 gttcaacttc tttttctttt tgttcttttc ttagtgctat cgcttctttt attttttctt
    12541 ttttagctgc atattcttct ttcaatgcgt ctttagcgtc accttttact tttttaagcg
    12601 ctgctttttc ttgtttagat aattcgtcta tttgtttatt aaatagtttt atatcttctt
    12661 cgcatgcttt tgtagctttc tttgtttctt cttctataat ctttgttatc ttttcagttg
    12721 cttttttgac cgagtcgcta ttattagcaa tcccttgtgc taaaccttca tcaacgaatt
    12781 taccaatctc agccataaca cgagatggag aatgtattcc taacactttt ctaaccgcat
    12841 cagcagcctt ttgccctagt tttttggctt cgtctactac tttataagca aagccggata
    12901 taccattcgc taagccgctt acaaaatctt taccaacttg caggaacttg cttgggaact
    12961 cttttatttt gtttacaaca tcagtcccga ctttttgaga tgcattaaca gcatcttgtt
    13021 tttttgagtc tataccttct cttagtcttg taaacatgtc gatagctgct tgttttaact
    13081 tggctggaag tgttttaaaa aatgtaatga cattattcca agtcgtcaca atgttatttt
    13141 taatttctcc tagttttgtt gttacagctg ttttcatgct ttcccacgca tttgtaagag
    13201 ttgactttat attttcccaa gtgttggagc aaattgtttt tagcccttcc caagcagtcg
    13261 aacatgtcga ctttatattt tcccatatat tgcttagagt ttgcgttata gactcccaaa
    13321 tggttattgc agtacttttc atactttccc acataccaga aagtaaatca cctattgcgg
    13381 ctaatgcatt gttaaatact tcttttatag attcccacgt attcgaaagt ccttgtttta
    13441 tattttccca aatttgcaaa gcgtctgttt ttaacttatc aaaatttcct gttacaacat
    13501 ctaaaattaa taaaaccgct ccaagcacca cattttttat aacttcccaa acattattaa
    13561 aaagctcttt tatactatca aaaataagtt ttaatttttc gataaagggt gcaaattttt
    13621 cttctaattg ttgttttata gcatcccaag cattactaaa aataagtttt atactttccc
    13681 aagttgtttg aaaaaataat tttatagact cccatttctc gcttatgcct tgttttattt
    13741 cttctatttt taagctgata ctttctttta tttctgtcca cttatttgta acagtaagct
    13801 ttatattatc ccataaaagg actgtatttt cttttaaatt agcccatcca atagatattt
    13861 tttcttttaa gccttctacc cagttccccg ctatgtcgtc ccattcttgc atcttacctt
    13921 ttaccgtatc atttaaaact tgccatttcg acttaatttc tcctgttgtc caatcaactt
    13981 tattcgcttg attttctgct tgtttctgtg cttctgcaac gactccttga tgcatttctt
    14041 ttgctttatt tattgattcg tctttttgtc ttgttgcttc ttctactact ttatccgcta
    14101 acttttcatt ttctgcgcca ccctctgttc taagctgtgc ggctattttt aatctttcgt
    14161 tatattcttc attagctgct tttatacttt cgtctttttt ctttattgag tttttaacta
    14221 cttccgcagc ttctttagct gacaaatcaa catgatttgc tttcattctt tccattattg
    14281 cagcttgctc tgcttcgctt ttactcattg tgtcaactgc ggtatttagc atatctgttt
    14341 ttatttgatt tatctctgct gattcttctt ttgttaatgt tctgtgttct tgactagctt
    14401 tagtcattat ctgatttact ttttcattgc tcttttttat cttttcttct ttgcttgaat
    14461 acgcttcttc agtatttttt attaactctt ctttttcttt gtcacttaaa tttttagaag
    14521 ttgcaaacat ttcttgcaaa gactgaatac cttgctcttt actctcttga agtttagcaa
    14581 tgatttgatt tgacatttct gtaaaattag atactattga ttgtttcatt ttctctgaaa
    14641 cagtctcacc actccacatt aattgattta aagatattgt tgtcttttcc tctaaatcca
    14701 taaaagcgcc tacagcttct tttgtagatt ctgatacact tttaccaaaa cggctaattg
    14761 gctctatagc atcctttgac atgtctttag cgactgttgc aaccgatatg cctagcgcag
    14821 taattccagc tatagctaca gctgcggggc ttgataatgc acctaaaatt gcagctaaag
    14881 caccaacagc tggagttgct gcggctgctc ctgtcgttac gactgccatt gctgctgaaa
    14941 aagtcccaaa agctcctacg accccaccaa tcataccaat tatttttcca ccaatcaata
    15001 aaactggtcc gagtgccgct gctaatcctg ctattttaac tatagtttct accgtgctag
    15061 gcttcatttc gtttaattta tttgtaagat tttgaaacca gctaaccgct tgcgctatgc
    15121 taggttttaa ggcatcatat atcttaagtc ccaattcctc aatagctgac attaaagcag
    15181 ttatagaacc cttgttattg ttttgcatag tcttagccat tttatctaac gcacctgtac
    15241 tattgccaac ttttttttca agttctgaat attcttctcc aactccggac aaaagagcct
    15301 gtaaagtaga tatttgtgtt tttccaccta tcatagatag atacattgtt cgttgttctt
    15361 ctgtcatgtc ttttgttttt tctttaagtt ccatcaagac attagccatg cctttaaatt
    15421 ttccgttaga gtcaaaagcg cttagtccta acttctccat cgctacgccg gcttgaccag
    15481 ctccactcgt caaatttatc ataattgaat ttaaagagtt tcctgcctcg ctgcctttta
    15541 gtcctctgtt tgcaagtatt ccaagcagtg cattagcttc cgaaagaggt acgtttaaat
    15601 ttttaaaagt acctccagac acaatcatag cttccataag tgcgtcaatg ttagtgtttg
    15661 aacttgcggc agttttagca acttggtcta agtaagttgg taactctttt acactaagtc
    15721 caagtgatga catagagtcg gttactaaat ccgaggttct tgccaaatca aggtttccag
    15781 cttccgacaa tcgcaaaaca ggcattaaag cctccattga tgtttttgca tcccatccag
    15841 ccaaagccat atatccaagc gcatccgctg cgtctttagc tgtttttgat gtagaagccc
    15901 ctgcttctct agctgctttt tcaagttgaa ccatttcgtc agctgttgcc ccactcaatc
    15961 cttgtacatt tgacatagat gcttcaaaat ccattccaag tttactagcc gctgctccga
    16021 ctgctagaat aggagcagta atactcatag tcattttttt acctacatct tgcatttgtt
    16081 ttccagccga gctgaattta ttacctattt cagtcatttt agttgccaac tgattccatt
    16141 tattttcctg ctgatttatt ctttctgttg tgtcatctag ttctgaacgc atttcagaaa
    16201 gtctcgactc tgcattatta actcgaatag accaattatc aaccgctgcc gagttagacc
    16261 ttattttttc ttcattttta gcatattctt gttctaaact atcaagttca gattttaatc
    16321 tttttgtttc ttctgcattt tcacctaacg tcgctttgct ctgttcgtaa gcactcttag
    16381 cttgattaac tttttcttta agttcaactt gcttttgtgc tgtgttgctt aaagttgttt
    16441 tactttcatt tagtttattt ttatatgctt caactacttt agtttgctgc tgtatagtac
    16501 tagataacat ttgttgctta gatttcaaac catcaagact tgttccaaaa tttttcactc
    16561 cagcgccaga atttttaaac tcgcttctta ttaacttcat ttgcctattt agattattaa
    16621 caccttgctg aaatgaacta ttttccatag cgacccgaac aactaattca cctacatctt
    16681 ccgccattct ctcacctcac ttgcaaaaaa ataaaccaag atttttatct tggtttattt
    16741 tatataaaac ttatattaaa ttaattttct tccgcaaaat ggacaatatt taatagtttc
    16801 cttactactg attcctaaat agtcgtaact tgctcctgtt agaaaatgct ttccgttttt
    16861 aagttctata tacatatcta tgtcggagtc gttagttaat aattcacctc ttacaactgt
    16921 atcatacatg ctaaacggtt ctgtattaat tttaacttca cagtacttac acatacactc
    16981 acatccttat aaccagctta tctggtcaat ataaacatca ttttcatttg gattattatt
    17041 atctttttta ttctctttca tatacacaag tatatctaaa taataaaata tatccatgtt
    17101 gtctatgtcc gtcatgctcc aatttttttc aaataaaaac atgctatata aatcttttat
    17161 aaaatcacgt ggagatagat acctattttc tttattagaa ttattttctg tatcttctcc
    17221 attacctagt tttttacttt ttcttcgaaa cctccactta cttttgataa atcttctaac
    17281 gctttattta taaaatcacc agctggataa aaaccatcta ataactcatc ttttgaaaat
    17341 tgttccccgt atatatcaac tgtaaaatca agcaattcgc ggaataattc tgtagagtta
    17401 agaccatctt cgattttatc ggttagtgta aaaactttat ctaattttct aagtgcaata
    17461 ggaggtgctt tgaatatttt ttcttcttca tttatagtta attttatttc catttttaat
    17521 tttctcctta tttatttaaa tttgctttcg ctggtgctgt tggttttact cctgttttta
    17581 aaaaatctgt tgtaaaaaat tgcgcattag taggtgcatt ttcgacgtcc gtatctgcgg
    17641 ttattttatg tctaccatca tgtattcttg gcataaattt aagtttaatc ttttgtgatt
    17701 gaaattcgat tttatcctct tttgtttttg cttcttcttc gaaaggttca cacacgcctt
    17761 tagttagcca aaccattcta ctcccgtttt gactttttgg agattcaaaa ccaaaagcaa
    17821 gattcggagg cgcgaaattt ttatcttcta tcagtacacc atctttatat tggtatccaa
    17881 ggataagcgc acgttcttct aatgttaagt cagcgacctc aatttccacc tctatagctc
    17941 ccatagccga agcagtctct aaaagctggt catccccata attttcagca gaatcaacct
    18001 taggtgatat ttttacactt ttagcacctg ttaatcttgt tattttagta tcgtattcaa
    18061 gtgtttcctc tgtatctgtt agtagcttta caattctata gtttcttaat cctataatag
    18121 ccatttctta atcctccttt ttttctgcaa aaaataagaa tctaaaaata gtatggtaac
    18181 tataatcaga ttcttttatt tcgtgtatac ttctttttat aaaattattt tttttaagaa
    18241 gtctttcaat ttctttattt atataactca ttttattctt actaaacaaa tctatttgta
    18301 tataatgttc tgtgcctact acttcatcat cagcatagcg gttttgttct aaataactaa
    18361 aaaaagttat atatgttttt tcttctccat caaacctttg aaatgaaaca ggaattttta
    18421 aaggttttaa tgtttctatt actaaatcat ttatattaat cattataacc ccaaccctct
    18481 ttttaatatt tctttcatta catttttagc ttcatctttt tttgattcgt atgcgggtgc
    18541 tagaaacggt ttagaactgg ttcctggatg atttactacc cttccttttt tcttaccttt
    18601 tttaattggt attttatgcg cagatgctcc aaactctaaa aactttccat aaaaaatttc
    18661 tgaattatcc tctttcgtaa taccaactaa aacatactta gtaccacctt ttttcttaac
    18721 tccacttact tttaaaccat cttttaactt tccgcttctt ttgcttaccc ttggtaatgc
    18781 atcttgcaaa ataacattac cgccagcttt tacagcttca tttaacagtt tatcgcctgt
    18841 tttacccatg ctttctattt tagataaaat agcgtcaaat ccttctgttg ttatctccac
    18901 actcatttaa acaacttcct catatttaaa ttttaattct ttacaataat attcattttc
    18961 tataaaatca ctagaattta aaaagataaa attttctttt ttaaatatat cttttatact
    19021 aatatatttg tttatattct ttaagctctt ataccaatat tctattttta ttgaatatac
    19081 aatactttta ttttcattat cagaaaaatt tgcatcatat tcattttcta taaaaaatat
    19141 tatatattct tcatcatttg aaaaattgtc gtattcttga aaaccaatac ctagatttaa
    19201 ttttttaagt atagtaacta tttttgagtg catactatct cctaactttt ttttacttag
    19261 attctgctgt tatttcaagt attttatttt cttcttctaa atttaagatt tgagttatat
    19321 tataaaattt atctttgtat ttaataacaa aattagttat agcattttgt tttatactta
    19381 aatctaattc ttcaatatat ctaattttaa actttttatt tgtagaagtt ttaatcgaat
    19441 tattttctat caattcttta ctatttaaat cttcaacaca agcccaaatt tttttataaa
    19501 attttattgt tacatcctca agaacatttt ttctctcttt gataaaaata gaaatatgtt
    19561 tatctaatac gtcaactaat tcagttaagt ataaatacac actagttttg tcattgctaa
    19621 tatcaagttt tactatgctg taaaattcat tatttaactt tataacatca cttgttttaa
    19681 ttaatctcat gtaaggaact tttaatttaa tagatacctt taaccctgta tcgtcaaatt
    19741 taagtttgtc ttgctctctt atatattcat tagaataaaa gagtttacca cttacaataa
    19801 actctttttc atctaacgca ttaccttcta tatcataact ttccttgtat tctccaaact
    19861 caacaatacc atcattaaaa ttattaaatt ttattttttt catatctata ttacctcatt
    19921 agctgcactt ttaatttgaa gtctaagaag ctctttacta aaattttcct cgaaatattc
    19981 aatagcattg tttcttacat atctgcaata attaaatagc aattctctat taaaattatc
    20041 tttaaaatcc agtgctattc ctgctatttc attttcaaag taatcaattc ctcttacaac
    20101 cattttttct atttttgcat cttcttctat ccaagttata tttagatatt cttttacctc
    20161 ttcaactaca cttttaatgt tttcattttc catatatttc acctatttcg ctctagcagc
    20221 tgacgttttt gtgtttgaat taatttctgt tgctaaagtt gtgtctaagt tttctatatc
    20281 aaatactaaa aatgaatcat tgtcttttgg cgctcctgtt gcatattgtt ttactagata
    20341 agttctttcg tcctctaaaa atttatattc gtctgaatac tctatttttc cgcttgaagc
    20401 aactcccata aaataatctt ttgccatacc agctattaat ttacctttag ggacagcaac
    20461 tgattgaatt atattcccag ggataggtaa aactccatac acataagtac cattagatgt
    20521 taacatagtt gtggcagcga aaattttagc ccagtaatca accggattta caagcattat
    20581 aacgcttggg actgcccttt taccattgtt tgtaagtggt gccataatct ctttgccaag
    20641 tgttattggt ttaaaatcag ccagtggttt tgcagttttg tctggaaata cgccttcaac
    20701 gactgcgcct tttaaatctt ttatcatacc tttcggctgg tcttttcctg ttcctgctac
    20761 tattcccatt tcaagcccca atgatataga ttcagtcaaa actactctta catatctgtc
    20821 taaccattca gcccctaaat caagcatggc ttttgcaact ggaagataag cagataattt
    20881 ataagcttct gtattaattt tatcaaatcc atgctctagc tcttttttga tagtatcatc
    20941 taatctaccc caccatgcag cttctgcgtt cgttttcctt attatccact ccgtaactcc
    21001 tgttgtattt tcaaaagtta tggcactaag caaagggtga ttttgttcta agtcgtcaaa
    21061 tactctatca aatacagtac gtggcatagt tatctctaag ttggtaaatc ctcttttttc
    21121 tataacttta ctatagtatg ctctttcctc gctagttaat tgcggcatcc ctcttttgtc
    21181 aagtattgct ctgtcagctg attctatatt agcaatagaa cgcgcttctt ttagtagatt
    21241 ttcttgtata tcttccgcca tcctcaaaaa cgcagttgtt attttttcct cgtcattacc
    21301 ctttattgct tccattaaat ctgctcttag ttcaacatta gttgcttcat ctaaattttt
    21361 aattgccatt tttattttcc tcctcgatta aatgcattaa aaaaagccga tactaaatcg
    21421 acatttcttt tttctatgtt atctttatta tcattttgct ttgtttcttc tttttgcgat
    21481 tctctaagct cctttataga tatatcactt ctacaattta tttctgtgtc attgtaagct
    21541 ggtatcgggg ttgcagtaat ttcaaacaat tcaacttccg taatatctct gtaaaatgtc
    21601 caatcatcat cccatcgagt tttagaattt acaatattaa aaccaaaaga acatccttta
    21661 atcaatccaa gccttacatt ttcaagtaag tcattaccat ctgttgtagc tggtatatct
    21721 acttcaaacc ttaacccatg ttcatcttct tctaaaatta gatttgagtt agttctacct
    21781 acaactttgt tccaatcatg atttatgagc ataaacttat ctctagtgtt atctgctaaa
    21841 gtttttaaaa atgcacctct tgaaattttt tcataaaagg tatcgcccca tctatcttgt
    21901 aacttagtgt aatcgtcgct aaaaactgct gcataaccac ttatcttacg gctttctaaa
    21961 ttactatccc ttatttccag cgacaccgtt cttttctcca tttccattgt tagcccctcc
    22021 tttcaaatct ggatttaaaa ttgactgata gtttttagtt acatagtgtt catcagccca
    22081 agactcgttt attttttctc tgccaagcat ttctaaattg tcatttatag aatttacacc
    22141 tattctaaat aataggtcgc ttgctttcga tattttttca agtcccatat tagcaatttt
    22201 ttgtgtatct acttttacat aactcttttc aaaaaaatta tctctaccat acatttttct
    22261 agttaattca tttgtaataa gttttgctac tggattgaca gaaaaattca agaaattatc
    22321 tgttatacct tcaactccag caacattacc ttttacaagt ccagcaggaa catgaaaagc
    22381 agcgcataca aaatccatga cgtcatcaat aatcgctctt atatccctgc tatcttttat
    22441 acttgaagct tttgtatttt ctgtatattt taatccattt gaaagcggta aaacagcatt
    22501 atcactttca aaataacgtt taaacttatt actcatcaaa tcgttaagtc gttcctgcgc
    22561 ttcttttgtc tgcgggtaat ttgtgtctat ttcaagtacg cccttttcgc tattattttt
    22621 tttataaccc ttcatggcac tacttaataa atctttataa tcattataaa gataatctat
    22681 tacagttttt atactttcaa catttaattt gaaatataaa acatctgact ctctaaaact
    22741 tctatctaat ttatagtttc taattgtaac atctttgtat atatcttcat aaaaaacata
    22801 cttatctaca ctaaaacttt cagctacgaa aagttgttcg ttttcttgta taactagaca
    22861 ttcattgtca tacacaagtc ttgtaattac ttcttgccaa aattctgttg cgttttggtt
    22921 ttggttaggt tctatattaa acaagtaata atttttttct ttaatagatt ttccattttt
    22981 aaatgtctga aattcactta aaactaaagc atttgcaata atagaaatac atgactttaa
    23041 cgcaaattct ttataaaata tcgtagcttc tagtttttta aaatattctc catctgctcc
    23101 tgacatttta tctttaaata aaaaattact tataaaattt ttaaaattca attcaccacc
    23161 tcattattaa tacgtataac aatcataaaa cttaattgtt gattcttgca tcagttcatc
    23221 atcttttgat aaagcatgta aaaacgcaaa aaagccatca gttttccgct tgattggctc
    23281 tatctttaaa aaagttttat ttcctttttt gtctgtatct acataaacat tattagtata
    23341 ccaacgcatc atcatgtcgt cgccccactt aattgtcctc tctgcgaaga tttgttctac
    23401 aagaggggct atttttgcgt gagttatcga cccatttcga acttcttcaa tcggtaaacc
    23461 tttgttagta aactcttctt ttacatgtgc agctctataa gagtcacaac agatttttaa
    23521 tatattataa tcttctgctt tttcaatgaa ccaatcagca atatattccg cttttatcgt
    23581 ttcatcataa attattgtgc agagaccttt ttgctttgct aattcaatat caaatttaaa
    23641 atttgttatt tctaaagact tataacatat aaaagtgtga tgcatgatat atcgtttttt
    23701 atctttttta aataacaata ccacgcttgt aaaatctctt atactagaaa aatctaatcc
    23761 tccaatgcac gaaaagcctt ttaagtctgg taattcttcg tttgttgcaa ctatgtcatc
    23821 ccattcagcg acaacagttg ccaaatcttc agctggcaaa ttaaatcttt tagttagtag
    23881 ctctatcatc atttgtggtc tatttttagc tttgtcaatg tcttttaaaa tttgtgtcct
    23941 taagtctgaa ttatacttta tacttgggtt tgccttttct agcaaattaa catcttccat
    24001 ttcttctata ctatcaagtt taaaaataag tggcagcatt ttagagtttt taatttcttc
    24061 atttaaaatt tgtttagctt cttctttgaa atcgtctaat actccacctc ttacattccc
    24121 atcagttgta atataaaaaa ttctaggatt ttttactttt ccaagcgcag aggtaaagac
    24181 ttttatatta tcataatttt cgtatgcatg aacctcatca aaaataatgc agccgggtct
    24241 taatccatcc tttgacttag cattatttgt gcggaacttt aaatagctgt tagttttttt
    24301 aaatgttatt acttctttag ttctgttaaa aaacttttta catatagcag gatgttcaga
    24361 taacatgtta taaacatcat caaaacttgt ttttgcttgt tcctctgaca ttgcaacaat
    24421 gtcaatacca taatttttta caccatgcaa gtgcgtttgt aaataattag ctaattggga
    24481 tataaaacca tttttcccat ttcccctacc catcatgata aaaatttcat catataaaag
    24541 ttcgtcgcct tcaaagcagc caaccactaa agcaacaaca aatttttccc aagcatacat
    24601 tttatagaaa tacttttcca tatattctat agctttttca actttttcat ggtcgatata
    24661 gatattaggt ttttttaaat ctttttttat tttcttaact gcaagtttca tttctttaca
    24721 tagaacaatt tcgcctttat cagccaagct gaaatactca tctatgtatt tattgtactt
    24781 ataattcaat atcatcatca cccaaaactt ttggcgtcgc ttttatacct agtttatcaa
    24841 gtaaacttaa catttgagcg ttatacttga taagctctga tacactatcg ttttttttat
    24901 agccccattg attttgacca tttttgtatt taacttgaac acctctagtt tttacatctt
    24961 ctattaattc attttttata tcccacattt ttaaatagtc ttcaactaag tctttgaagt
    25021 attcttctgt catgttattc tcttttattt gtcttaataa atcttttctt atagagtttt
    25081 ttaaattatt tcccgactct tgcaacccat ttttcacgca accctttttt ggggtgcagt
    25141 tgcgagtcca accccctctt tttctccaac ttttcaaagt gttttcgggt atgttatact
    25201 tggctgacat ttctttataa gtcataccta aaacgtagtc attctgtacg tctcgcctaa
    25261 tttctaattc ctcattatca tccattttca ccacctcatt tttatgtttt ttctgcaccc
    25321 gcaaccatga attttggttg caagaccccc accccccaca ccttttgtta aattggtgtc
    25381 tccttgcgga gccatgtacc tacctcggtt cacaaaattt cgagctgaaa gccagttttt
    25441 tcaatagggg ggctatctac cagcgttctt cactaaaaaa ttttttcttt ttctcttgat
    25501 taatttttag tattttttcg tgaatttcgt tgtgacaaag gttgcacaag cttgttaggt
    25561 tattaagctt caaagcttcg ctaggatact cttttatttc tttaatatga tgcacacatt
    25621 cggctttaga tactttcttt ttttctttac aaatctgaca ttcattatta tctctttcaa
    25681 gtgctttttt tcttaatttg cgccagtctg tacttctata gaatatatca agtctatcaa
    25741 ttaaaattaa ttcttttaat ctatctagtg tcatgtgctt ataactcatt aatatacaac
    25801 tctcctagac cgtcgctata ctctttcatg tcttgcaata gcttgacttc atcatcttta
    25861 agcttcttat attcttctct cttatgttta atataatcat cctcatatga tacaacaaac
    25921 ttctcaaagc atctgcgaca catgaagtat gtaacagtag tattatcaat aactttagtc
    25981 tttaaatctc tattatttac attaactttc tttccgcaat tattacattt aaacttacca
    26041 tacttattca tagtgatact cctttaattt cctagttgag tttaacataa ggtatattct
    26101 gttaaactca tttaagtatt atcaaacagc cttacacttt agtattaaca atacattcaa
    26161 gactttatta ttagactata ttttatccag tttaacgtga cctttttatg ttaaactctt
    26221 aagctaaaag tatttaatat tcctatatgc tttgtttaaa tcatcctgtt caattccaat
    26281 ataccgcaag gttatcgtag ctgaactatg attaaaaagc ttctgcaatg ttacaacatc
    26341 atgtgttctt ttatagtaat gataaccaaa agttttacgc attgtatgtg tgcctagatt
    26401 atctatacca aacatttcgc ctacttctcg tattatctta taagccatga ctctgcttat
    26461 agctttattg gtctgctctc tactcttaat taaaaattca ttttgatttt tatcttttgt
    26521 atattctttt agtattcttc tcaaaatagg attaacctcg ataggcttag tcttacccgt
    26581 cttactttct ttaagagtta taaaccgttt gtcatgaaca tcttttattc taagctttaa
    26641 tatgtcccct actctaagtc ctgtatatat gcccatactg aagagtacat tgtttctcat
    26701 gttagtttct tctaaataag cgcatatgct ttctagcttc tctaaatctc tgataggttc
    26761 tacaaaattc atttactcac ccccttcctt tttttagcaa taaaaaagcc taaactttcg
    26821 agcttcaagt ttagacttta ggtttcgggg gatattcagt tgtcaatgta cacttttttc
    26881 tatgatacaa ttctaacatg ttttctttag aagcgaagta taaaaatagt cttttttctg
    26941 taaaaataat gtttattcta aagcttcatc accatatatc attaaagcta ttttattaat
    27001 agcaatagct tttttgttat aaagactagt tctatcataa tttaattccc ttgccatttt
    27061 tgtaataggc attttcccat cccagctata aaagtatact agttctataa ttttttgttc
    27121 tatctctgat agctctttta aataaatatt ataaaactct agctttcgct ctataatttc
    27181 aatttcagtt tctttgttgt agatagcatc ctctattgtt acaaccatgt catctatacc
    27241 ttttacactt ttttgtactt taaaccctaa ttcttcataa ttaacttctc tatagttttc
    27301 tttgtgttta agaattgcta tttctttttt taatactctt aactttctat atttatctcc
    27361 tagcattttt aatgcatttt ccactttgtc aaaatactct ttttttattt tcatttttac
    27421 acctcttgca ctttttgtta taaataccta actaatcctt aaatttagct tttgggacta
    27481 gttaggtatt ttgtagcatt tccaacccgt ctatattatt caaaatattc tgtattttta
    27541 ttttgttttt ttgttataag acttcatttt tttaagttta aataaaatct atatttataa
    27601 agcattttat ctattttaat ttaaaaatta atctaattgc gttttatatt gcctatttac
    27661 tttaatttat ttttaaataa ctttttttca tttccaattg gttttgcaca ttgagaacaa
    27721 ttccccttga acatttctga acagctagga cacattttcc caactggagt ttttatagaa
    27781 aaaaattctt gaccacataa aatacattcg cctactacta gttcatctaa atagtctccg
    27841 cacaaacatt ttctacacat actcatttta actcccccct atgctaattt attttttcga
    27901 gtttccattt tctttttctt agttttttat tatgtagctt caaaccttcg cgtatttctt
    27961 tatcaatctt taatacttta aatagtgtaa aaattgcttg aataacatcc aaaccttctt
    28021 ccattatttt tttgttatct tttaattcaa tagcttcttt aagttctaaa acttcttcaa
    28081 gtactttttc aaattgttct tttgctgtca attctggtat atttgcaatc attttaaaat
    28141 tcatctttta ttttctcctt tttatatttc ttctaaaatt tcttcatgtt gtttttttat
    28201 tgcatcaaga ccttcaagta tcatttttct tataatttct ttcatgtatt catcatgtgt
    28261 aaatttaaca atttctccaa ttttattttt cttgtcaata aataaaattc taacttctgt
    28321 ttctccgatt tcaatttctt ttaaaatatt ctctaagtct tttatacttt cttttgttgt
    28381 gcattgtatc tcctctttaa tcttagttaa aaattcttcg attgttgttt ttcccatttt
    28441 atttttctcc tttttttatt cttctgcagc tttcaactgt aaagtcacta tctcttcttt
    28501 taccttctat aaaatttaat tgtttgccac catttttttc tatatattca gatatttcac
    28561 ttttgtcttg gcattcattt tctacatatt caagtatgtc aagtatgcac atttcttctg
    28621 gaacttcaat aataacttta tgttttaaaa atatcgtttc ttcaatttca attctatact
    28681 ctttcatttt ttctcccctt cttttctgta ttaaaaaaat ttatctgtct ttcattttct
    28741 atttcttcat cactaaatcg tttttccaag tcatgcactg tagttccatc ggctttgaaa
    28801 gaaacaggac tatccttatc caatttaagc atacccccca caaatctgga taatatcttc
    28861 ttagagttct aaggctctct aaactttgtt taggacataa gtaacaacca gttcgtttaa
    28921 atctatgatg tattttataa tagaaccctt tttcttctaa atacttcaag caatcttttt
    28981 cagtcatttt tgcttcgtaa agtggtgcta tacagttttc ttccagtctt ttatatctat
    29041 taggttcatc aaaggcaatt ccaatgtacc ttttatgttc tccaaccgaa ttgaaatatt
    29101 tattagcagg agcaagtttt aatcgactat tacaccatgc tcccaaggtg tatggaaaac
    29161 cccatatttg ccctttacgc ttaccttgtt tattaacagt ataaaagtat tcctcaaagg
    29221 ttttttctgc tttaattctt gttattttaa agtttattct tttttcaaaa tcatctatta
    29281 tgttataaat ttcttcaaat tctagtcctg tatctataaa tacgatttca tcaagagtta
    29341 atttcttttc taatattaga aggagcattg ctgctgaatc ttttcctcca ctaaaacttg
    29401 caatatactt cattttttcg ccccttctgt ttctaaattt ttttctcttt ttttcttaca
    29461 tttcttagaa caatatgcaa ttttaccatc cgtataagaa taaatcgttg ttccacacca
    29521 tccgcaaatt ttagctgttt ttttatttat attagacatt attatccctc caactttaaa
    29581 atggtatatc cgggtcatct atagcttgaa atccctgttg gtctaaacct ttcggttcaa
    29641 acatatattc tttttcatta tcctcttttt tatagtctaa aaatttaatc ttattagcat
    29701 gaacttttgt ataagttctc ttctcgcctt ctttttcata actattaact cttatagacc
    29761 cttcgacccc tattagccta cctttagtca gattattagc acatacttct gctaacttcc
    29821 ccatcacctc aataggtata aaatcagttt ccttagttcc atcttttttg atataatctc
    29881 tatctattgc tattgtaaaa gtagatacag ctgttccaga acctggtata tatttcaatt
    29941 cagggtcttt tgttagtctt ccaatcattg caacattatt cattttaaac cacctttcac
    30001 ttttttatat ttcttcaatt ccaaaatggc gcttcttctc catttctttc atcatttaaa
    30061 acttcaacta tcttataatt ttgtaaacta tcttttcttt caagtgactt tatccagtcg
    30121 taaaatttac ctctatattc ttttttataa acatgattcg gaaggtcgtt ccaattatct
    30181 agtaaactat caaatttctc taatgcttgt gtaacactaa tcttattcat tttctccctc
    30241 cacttgttct tcaattattt tatctacgca gcctaaacag aaatacaacg caaaacttaa
    30301 atttaaagtt tcttcttcat acttcacata attattttct tctacattta ttgttctttc
    30361 gcatctagcg catgttacga acttatccat tattaaacct ctccttatat ttcttccatt
    30421 tttcgaacat ttttttcttt tagttctata aaaaaatttt ttaatagtat tttttcttct
    30481 tctcctactg aaaaatgaac gcaagataca tcacaagaac ctcgtatgtt aaactccata
    30541 cttaattctc caattccaaa ataagaatca atatttctta tcattgtatc aatgcctttt
    30601 cttctatcct ctaaaacctc gtatacctta attttttctt ttgtttcttt gtattgttca
    30661 tacagtaatt cctgctgctc gcataatttt tcatatttat ttatgttcat ttttgcgctc
    30721 ctttttaaat cttttatttc tacaaggaaa ttatttgctt tattttttca attttattag
    30781 atatagaatt aatattttta tttttaattc taatactttt agtcctgtta taaatcgcaa
    30841 tagctttcct tatatttttg tttaaaatac aatctatgaa taaattataa gtttctaatt
    30901 ctaaagcctg ttctattaaa atattttcaa tatctattat gcattcttct gactctaacg
    30961 catcccttgc aaaattttct aaactctttt ctaaaccttt tatatgtttt tcacattctt
    31021 ttaaatattc ttctttttgt ttatttcctt cttccaactc ttcaattagt tgtttcttaa
    31081 ctaatgtata actacctata ttcaaaattt tccctcctgt tcttctattt ttttaacttc
    31141 attacaagca atagaaaata attctccttt acttagattt ttatattttt cttgtagttt
    31201 cttttgtttc ttactaatca aatcagcttt ttctaatata ctcatctctg aaattttctt
    31261 ttgcatttac tttgctcctt cttgttctgc tacagtaaaa tttattatcg tctcatttcc
    31321 cctgtgctat actaaagcaa aaggaggcga tactatggtt actaaccaag attgtataag
    31381 agatatttta ttatttattg aatctaatac aactcccatt tctcctgtat tacaatttga
    31441 tactatacta gataatctca aatatgatga atcaactatt attcatcata taaatttaat
    31501 ttatcaaaac agtctcgttg atgatgttaa ttatggtgat gatactgttt tagaggtcac
    31561 gcagttgtct ttaaaaggct atcaatattt agatgaaata cgagacagca ctaaatggaa
    31621 taaaataaaa agttccacct caagtttttt aaatatgtct ctacctatcg caatagagta
    31681 catattaggt aagttttaat agttttaaat ataaggttta gattatagat atttctaagc
    31741 cttatcctag tatttttcta atacgttctt cttcttttag tagttcactg atagtgtgtg
    31801 tttttataaa accttctgaa aattggtgct gacctttttc aaatttttta attagtacac
    31861 tttttttgct gtcatctctt tctattgctc ttaaaaatga ttcataaaat atatgctcct
    31921 tgccaaattc ttttaaaata tattccttgg tagaatcatt atagccatgc tcttttaata
    31981 cttttatttt ttcttcataa cttaaaacat tattttttat cattttttca ctctcctttt
    32041 tcacatgtaa agatactaat ttaaatattt atttcttcat tttcttaaac tgctttcttc
    32101 ttataatact ccacgaatta ccatccaaac atttctcaca aatttcaata ttttttattt
    32161 cttttgctga actcaaataa tctcgtgtta aaaaaggtat tttaaataca tcttcttgat
    32221 tttctatttt tttagaacaa ataaaacaag tacattctga atcactagta tctttacctt
    32281 ttgaaacact gtcatgattg caagatattg tatccgtttt tgctgaacta atttcttcgc
    32341 aacttgcaac agtttcagaa ttttctttat ctccataatg aattttataa atttcttcta
    32401 tatctgcatt ttctaatcct agataagttt tatatgcctt ttcttttcta tcactgtgct
    32461 tatgcttttt tattatatct aaagcattta tttcatataa tagagcatca ttccaaggtt
    32521 ttttaaattt gttttcattt gcttttatta gttcttcgtt acttaactcg tttacagttt
    32581 cattacaaga aacaacattg ttactctctg cttttataac tccaaaaagt tcaaccaatt
    32641 cttttaactc tcttacacta ttaatttcca tttcttacac catccctatt tttttattta
    32701 aatttaacac tttgactttt ctttataatt gcatcaagtt ctttttctga atatttatta
    32761 aatgtttggt caaaattagc aaatttatta ttatttgtct ttgtttttcc tttgacgctc
    32821 tcattgccct ttagagcctt tttaggtgtc tcgtttaagt aagactcgaa tttgtttccg
    32881 aaaagcgtct ccgggcgtaa ataagcgttc attttatcat catctagcca gtttaacact
    32941 ttgttatcta tcaccttgta aaattcttct tctgtaaagc cttctttgag tcttgcatca
    33001 atcaaagata tagttttctt tgttgtactc ttaaaagatt tatctgctgt tttatttaag
    33061 taatcaacga ttcttttata tatctctttg tcttttgtct tttcttcttt ttgctctgca
    33121 gaactatata tattattagt taaattagtc ttgttaatat tagtcttgtt actcagcacc
    33181 tcattcctaa catgtacagc accacatgcc gtagggttaa gcacctcatt cctaacgtta
    33241 ggcattgtgt gctgcacctc ttgtttagct gataataata tatatagatt gctttctttt
    33301 tcattactac cttttcgctt gcggtttttt cttataagta accctttttc ttctaaactt
    33361 ttcaaaacat ttgatacttg cctttcgctg catccggctt ttttagatat tgtcttatag
    33421 cttggaaaac aacaactttc ttcatcgcta tatctaatta aaactatata aatcatcttt
    33481 tcgtatatgc ttaaatcttc tctatcaact aaactatttt ctgcccaaaa ccaatctctt
    33541 ttccttgaat cttttaaaag ttccaatccc tcaccccctt ccacttataa attatttatt
    33601 aagatagtaa tttaagttca tagtcattga atatcaaatc ttctttagtt aatactttgc
    33661 atgtcatttc ttttatttct tcgtcataat acgttaatac tatttcgtct ttatctatat
    33721 atgtaacaat acattttcta tcatgattaa atttcacatc atgcaatcta ataatttcgc
    33781 ctatttttat atttttactt tttagtaatt tcaatctatc cacctcttaa tttcgaatat
    33841 tctgattctt tcatatatat tttttacttt tttcttcttc aatttcaaaa agatattcgg
    33901 tacttaaatc agggaagaat attgtttgta ttttttttgc ctcaatatat tttagtctat
    33961 taatactatt taacttggcg caaattgtac ttacatttaa atttaacgct tttgctattt
    34021 tttcatttgt tatatttttt ctcgccattt ctgcttttaa atttctaaac attttaatgc
    34081 tcctttctga atttattcac gaaattgcgt gtcttatatt tcatataata cactcaattt
    34141 cgtgaatagt caatatgttt ttgtatttta tttttgcaat ttcgtaaatt tttcttgaat
    34201 ttttacgatt ttaccattat attaaaaaca aggtggtgat taaatgaata tagaagaacg
    34261 tttaaaacaa ttaatactta gcaaatataa aagcataaga gcttttacaa aagaagttaa
    34321 tattccttat tctacagttg atactatgct taagcgcgga ataagtggta ctagtataac
    34381 aacagtatta aaaatttgta acgctttaaa tattgacgct gatgctctta ttgacaacga
    34441 actaaaagaa aaagaactat cttcaaagat acaaacaaat cagttcgaac aaaaaatttt
    34501 aaaaatgtat aatgctctcg atgaacatgg aaaagatatt gtatttacta tattagaaaa
    34561 agaatatgtt agaattaata agctctagta ctagagctta tattttgttc tacactctaa
    34621 tattaacacg gaaaaccatt ccaaaaatat tcgtacgacg aatattccga ctttaattta
    34681 caaaatttac caattaattt gtctattttc taaattgtaa aaaatttcta ttgattttaa
    34741 tattttttaa tactatagtt taatttcgac atggagtctt tattaaaata tcatagaaaa
    34801 aagaaaaaac tcactcaacg tcgattaagt gaattgacag gaataagtca aagttacatt
    34861 tcaaggatgg aaaacaaaaa atttaaacac agcccaacct taactcaaat aattttatta
    34921 gctgatatat tagaaattga ccaattgatt ttatctgaat tttttttgga aaaagaaagg
    34981 gagcatttaa aaaatactaa aaaatataat aaaaaagcag ttaaaacact tagcagggat
    35041 tttttaaaag aatataaaaa taaggactag gtaattattt atacctagcc ccttttttta
    35101 ctgctctact ttaatttctc ctagctcaat ccagttatct ttatataatt ccggaaattt
    35161 cttttctaca tctgattttg atgctccttg atttgcgtac tccattgctt caaaaagtct
    35221 tgaataatct ttcaggttat attttaaaac tatttctttt acattcatat tcttttcaac
    35281 taatatttta acttgtgcat caaatttgta gttagctggt acttgttgat tgtctaattt
    35341 atcagttact tttatgtctt taaattcgta accatctgta ccgactgcgt tccatcctgt
    35401 ttgaaataat ttaactgctt tatctgtttt attttctact tctacattta caacttcgta
    35461 cacataatca gctgcctttt tcttttcgat tccatcacta aaatattctc cattttcgtt
    35521 aaaacttccg tcttcgttta tatctccttt tatatcttct tttgtaacat cttttacagt
    35581 tattttaatt ccatcaacct cattttcatt tgctttcttt tcttttttag ttgtgtttcc
    35641 agtatctttg ttattagttg atgaacaagc aaccaaccct acacttaata aacatactgt
    35701 aattaataat aatacttttt tcatcctcga ttcctccatg tttttatgtt ttgttatata
    35761 tttcaacatc aaaacttata ttcctttaat tttctattct agtagtatga aaataattta
    35821 aaagaataat acctatttat ttccattcta agcatttttt tatgctattt aacataaatt
    35881 atttataaca aacagaaaaa tcgtttctgg tgtcttgtat cgcttctaaa tgatattcta
    35941 gtttcttaat caaataatca ttttcttttt atccaaagat acattctaat agtttcttta
    36001 cttttgaaaa atgctaataa tattttaaat agcgaccacc actttttgag acaagttaga
    36061 tttctaatta agttaagtac tttaataaat aaatacaaaa gatacatatt ttgttctcta
    36121 taatacaagt tctctataat aatatattct ctatatattt actgcaccac tttttgcact
    36181 accaaagcac cactttttgc actaccaaag caccactttt tgcactacca aagcaccact
    36241 ttttgcacgt agtaagaaat ctaattaatt tttaaaaact tattaacatg ttatcaacat
    36301 aaaaataatg gttatcaaca taaaaatcaa agttataaac agcattgtta tatttagaca
    36361 taaaaataga ccttttttaa agaaggtcta ttttttacgt gcatttttcc attctgaaaa
    36421 actacatagt ctatataatt tttgtatcct aggaactttt ttattctttt cttcgtccca
    36481 ctcaaattta ttttcttttt ttacttcgat atatttgctt acttcaaata ctgttataat
    36541 ttttcttatt ttacttctgt tatttttgct atcaccacat aacccgattt tttcacaaat
    36601 aaatttttca gtcatacatt taaaactatt ttcagttgtc atgtaacata aaaggcaata
    36661 aacttttatt gcattagtat taaatgcaga aattaattct tgtagcatat catgatgaat
    36721 tgtaacaaat ttatgaacgt tatcgttgta tcctgtactt gtaccatagt ttaatctata
    36781 aattattccg ttgcggctgt tttctatttc aagtacttta caatctaaac tattgagctt
    36841 ttttatattt ctctctaaag tagtacgagc aacccctatt tgtttagcta attcttccat
    36901 tttaaattta ttttgataca aatatctatt tttttctata tgcataattc tcatgctccc
    36961 tttacttata agcattaaag cgccaaactc tttagcacaa taattttttt catttaaaca
    37021 atacgtaggc attggtaatt tataattttt ttctaattct tttgcttctt ctaaagacat
    37081 tttatttccc ccttttgacg gggcttgaag cacttttaac taattaagtt aaaaatttca
    37141 aattattttt aaccttaaaa cattgattta taagttgttt taatctataa tataacttat
    37201 aaattagtta aaaaaggata taattatatc ctataagagc ttcaagctcc gttggtaagg
    37261 aataagtcga gtcgccaaac aaacgcttat tccttttatt tgtttttgta atctgtaata
    37321 agttaatatt aattatagca taaatataaa ataaaaaaat atattgattt tgaaaataaa
    37381 ttatatttta aaagacttag tacacttact aagtcttttt ttatgtaaat atatgttata
    37441 ataattttag cgaggaaaaa agtgattgaa aaagcgtaag agtggctatt tccatattta
    37501 aacgccaaat tccataacgg aaggaggtgg aacaatatgg tgataaattt tttattgagt
    37561 atactagctg gtgttatatc agcttccata tatgataaaa taaaaaacca ctcaaacgcc
    37621 aataagagtg gttcaagaaa ataagttatt tttcaaaaca ttggaaatag ctactcttgt
    37681 gtaaagtaaa tcattatttc cttgctttta ttatatcaca ttttttaaaa aagatacaat
    37741 tttacatcac ttcatatatg ttaattagtt taaaaataca aaaccactct gcgcaaaaga
    37801 gtggttggga atttgattta aaaatcaaat tcaaaaagtc tagataattt tttactttag
    37861 acgaaaactc tactcttatg actgaaatac agttctcttg cttttattat atcacatttt
    37921 ctttaaaaga tacgaattta tatcatttct aatatactaa aatctttact ttttaccaaa
    37981 atttgtttaa aaataggaga aaactattgc ttttgacgcc ccgtcatgat ataatatatt
    38041 tatagagaag gaggtgagaa agc
//
LOCUS       DAYAOO010000035        37993 bp    DNA     linear   BCT 12-OCT-2024
DEFINITION  TPA_asm: Clostridioides difficile isolate ST8-SSI-h139-18
            SAMN40601845-rid21577343.denovo.035, whole genome shotgun sequence.
ACCESSION   DAYAOO010000035 DAYAOO010000000
VERSION     DAYAOO010000035.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN40601845
            Sequence Read Archive: SRR28438827
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 37993)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 37993)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-MAY-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-MAY-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002157583.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002157583.1
            Genome Coverage       :: 163x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/11/2024 16:19:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 4,038
            CDSs (total)                      :: 3,963
            Genes (coding)                    :: 3,930
            CDSs (with protein)               :: 3,930
            Genes (RNA)                       :: 75
            rRNAs                             :: 6, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 60
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 33
            CDSs (without protein)            :: 33
            Pseudo Genes (ambiguous residues) :: 0 of 33
            Pseudo Genes (frameshifted)       :: 7 of 33
            Pseudo Genes (incomplete)         :: 25 of 33
            Pseudo Genes (internal stop)      :: 11 of 33
            Pseudo Genes (multiple problems)  :: 8 of 33
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..37993
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN40601845-rid21577343.denovo.035"
                     /isolate="ST8-SSI-h139-18"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Denmark"
                     /collection_date="2018"
                     /collected_by="Statens Serum Institute"
     gene            100..738
                     /locus_tag="ACGI5H_001971"
     CDS             100..738
                     /locus_tag="ACGI5H_001971"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889844.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9697674.1"
                     /translation="MSNQRKDFDITNDMFQESIPITTKIILEDMPSNDELNHVFSKGC
                     ERKMKKRKIVLITLLLIGVLLLGSILYNLFLGKTANISMLKESWNFDIPIPNKEIEVF
                     DTQDSINGDGQSYFIQGFSEKNFKKVFNLKGGIVVSKDNINEIEKYIDKFKRDSVNIN
                     KSNKNKIEEDFKKYKLEVKKDDKYIYKRNYENYVVLIIKKDEQKLYSLIWNQ"
     gene            complement(1211..2569)
                     /gene="rlmD"
                     /locus_tag="ACGI5H_001972"
     CDS             complement(1211..2569)
                     /gene="rlmD"
                     /locus_tag="ACGI5H_001972"
                     /EC_number="2.1.1.190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436249.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008649 - rRNA methyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (uracil(1939)-C(5))-methyltransferase
                     RlmD"
                     /protein_id="HFG9697675.1"
                     /translation="MLSKNEMYIVDIVDIGQGGVGVGKYNGITVFVEGGLIHDKVKVR
                     INKVKKNYAVGDIVEIIEKSPFRVKRVCSDNLRDCGGCQIQDLDYNKQLEMKTNEVKQ
                     VLSRIGKLEDVEVHDTIGMDNPYRYRNKAQFPIQKNNGIPIIGFYKKKTHDVISTEKC
                     VIQHEINDKIVKIIKTYIRAYKVSIYDEKTHTGLIRHLVTKIGFTTKEVMVVLVANGN
                     KLPYLKELASVLKENIPGFKTLVVNVNQKDTNAILGRENIVIYGDGKINDYIGDLVFE
                     ISPLSFFQVNPVQTKVLYDKALEYANLNDTDTVFDIYCGIGTISLFLAQKAKKVYGIE
                     IIDDAIKDAKINAKLNNIHNAEFYVGKAEEIVPKMYREGKTANVVVVDPPRKGCDEKV
                     LETIVSMNPERIVYVSCNPSTLARDLDYLNVHGFKCVEAQPVDMFPHSTHVETVAKII
                     KQ"
     gene            complement(2744..4504)
                     /gene="pyk"
                     /locus_tag="ACGI5H_001973"
     CDS             complement(2744..4504)
                     /gene="pyk"
                     /locus_tag="ACGI5H_001973"
                     /EC_number="2.7.1.40"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436250.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000287 - magnesium ion binding [Evidence
                     IEA];
                     GO_function: GO:0004743 - pyruvate kinase activity
                     [Evidence IEA];
                     GO_function: GO:0030955 - potassium ion binding [Evidence
                     IEA];
                     GO_process: GO:0006096 - glycolytic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate kinase"
                     /protein_id="HFG9697676.1"
                     /translation="MLNNVKKTKIVCTLGPASQSEEVLTQLMQNGLNVCRFNFSHGSH
                     EEHKERIDMAKKVREKLNKPVAILLDTKGPEIRTGNFEDPEVFLEEGQKFTITMKDIM
                     GTKEMCTVSYKGLAEDVKSGDSILIDDGLVGLRVKEINGEDIVCVVENSGIVKNHKGV
                     NVPGVKINLPAITPKDISDIEFGISQGIDYIAASFVRKASDVLAIREVLENNNATDIQ
                     IISKIENQEGVENLDEILKVSDGIMVARGDLGVEIPTEEMPIVQKMMIKKCNELAKPV
                     VTATQMLDSMIRNPRPTRAEVTDVANAIYDGTDAIMLSGETAAGKYPVEAVKMMATIA
                     KRTEETLDYDRLLKENGTNNVTVTDAISHATCTTAVDLNASAIITSTSSGYTARMVSK
                     FRPKSPIIATTNNEKTMNKLALTWGVYPVKSSVAGNTDEVIEKAIEAARQADYIDNGE
                     LVVITAGVPVGVSGTTNLIKVHVISEEIVQGIGVGTQTVEGKVRIIKNGNACVDFNEG
                     DILVSTATDAEMNNYIEKAGAVVTENGGMTSHTAIVGINLDIPVIVSAADITNLVKDG
                     EVVTVDASRGVVYRGSTRVL"
     gene            complement(4556..5515)
                     /gene="pfkA"
                     /locus_tag="ACGI5H_001974"
     CDS             complement(4556..5515)
                     /gene="pfkA"
                     /locus_tag="ACGI5H_001974"
                     /EC_number="2.7.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416974.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006002 - fructose 6-phosphate metabolic
                     process [Evidence IEA];
                     GO_process: GO:0006096 - glycolytic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="6-phosphofructokinase"
                     /protein_id="HFG9697677.1"
                     /translation="MKTIGLLTSGGDAPGMNAAIRAVVRSAIYYGCKVYGINRGYKGL
                     LEEDLTEMNLSSVGDIIHRGGTILKSSRCEEFKTEEGRLKAVKILKKYKIDCLVVIGG
                     DGSFAGAQKLSDLGFPAIGIPGTIDNDLAYTDYTIGFDTAMNTIIDAIGKIRDTSSSH
                     ERVNIVEVMGRHCGDLALYAGLAGGAETIIVPEVEITVDEVALRLKTTQKRGKRHSII
                     VLAEGVGSASDLEKELKKESGADLRVTVLGHVQRGGSPTVSDRILASRLGVRAVELLL
                     DGKSARVVGIKENKIIDLEISEALAQKKVFDKEAYEMAKILSI"
     gene            complement(5724..9293)
                     /locus_tag="ACGI5H_001975"
     CDS             complement(5724..9293)
                     /locus_tag="ACGI5H_001975"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008408 - 3'-5' exonuclease activity
                     [Evidence IEA];
                     GO_process: GO:0006260 - DNA replication [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit alpha"
                     /protein_id="HFG9697678.1"
                     /translation="MNKDFAHLHVHTEYSLLDGFSRVKKLIKRAKELNMSSIAITDHG
                     CMFGVIDFYKTAIKEGIKPIIGCEVYTAARGLRDKDPNYDKYQGHLVLLAKNMEGYKN
                     LIKIVSTSYVEGFYYKPRVDMEELKKHNKGIIALSACLAGDVARALMNRNYEKAKQFA
                     LDYRDIFGEENFFLEIQDHNLPEQKEVNSGLVKLSKETGIPLVATNDVHYVNKEDSKI
                     HDVLMCIQMGKTLNDPNRMRFGSDEFYLKSREEMEELFPYALEAIDNTVKIADMCNVE
                     FDFNTIHLPKYDVPEGYTPETYLRELCFNGLKERYDNPSNEILERLNYELDVIEKMGY
                     VEYFLIVWDFINFSKENNIIVGPGRGSAAGSIVAYTLKITDIDPIKYSLLFERFLNPE
                     RISMPDIDIDFCYERREEVIDYVKRKYGDDHVAQIITFGTMGAKAAIRDVGRVLDIGY
                     NKVDKVAKEIPFALGMTIDKALDTNPNLKELYDQDPETKEIINISKQIEGMLRHASTH
                     AAGVVISKNPVDEYVPLYKHQDAITTQFTMTTLEELGLLKMDFLGLRTLTVIRDTLDL
                     IEKNRVIKNYTEKIDFSKMDYDDPKVYEMLSSGNTLGVFQLESAGMRSFMKQLKPDNF
                     EDIVAGISLFRPGPMDSIPAYIKNKSNPKDVTYLHEKLKPIMEVTYGCLVYQEQVMQV
                     VRDLGGYSYGRSDLVRRAMSKKKMDVMEEERQYFIHGKFDEDGNIEIAGCIRNGVEEE
                     IANKIFDDMIDFARYAFNKSHAAAYGVLAYETAYLKTYYPVEFMAALITSVMGNTDKV
                     VEYIRECKALEIDVLPPDINKSFSKFSVEGDNIRFGLAAVKNVGVNIINNIIAERESN
                     GLFVDLVDLVKRLDQKDTNKRVIESLIKCGAFDNISENRASLMAGYESLLESVSMDRK
                     KNVQGQISLFDAFGDSEEDSDFQQIYSLPKRQEYEERERLNLEKEVLGMYVSGHPLSQ
                     FEKELQEKTSMDNGKLNSLKEEEESYLQMNETDVIMGGMIVTKTIKTTKRNEIMAFIE
                     LEDLYGAIEIIVFPQLLQKYNVILNEDNIIYVKGTLSIKEGENAKLIAREIKDINDDT
                     DFADRNYNSGRTRNVENIKPESGKKLYLKIDSMSDTDTTNNIVEIAKQYPGNDSIYLY
                     PMDENINGKRKAYKMTGALTCICDEFINNLEELLPKDNIKVKA"
     gene            complement(9450..10397)
                     /gene="whiA"
                     /locus_tag="ACGI5H_001976"
     CDS             complement(9450..10397)
                     /gene="whiA"
                     /locus_tag="ACGI5H_001976"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436252.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0043937 - regulation of sporulation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein WhiA"
                     /protein_id="HFG9697679.1"
                     /translation="MSFSTETKNELARVISGNECCNIAELSALVKSGGSIQIVGYKKL
                     NLKITTELNSIARKVFKLLKKNFNINTTISVNKNQMLKRNNSYVLMVTSEMGSEMLLK
                     KLGILEDKEGFFTINKISENLIKHEGCKRAFIRGAFLGGGSISDPEKNYHMEFVTNNE
                     EFADSLKELINSLGFNSKIVARKNNHVVYIKESEQISDLLSIIGGHHALLSLQNTKIV
                     KEMRNNVNRIVNCETANLSKTVNAAVRQVENIKLIQETIGISSLPENLQEIAKIRIEY
                     EDMTLKELGEMLEPPIGKSGVNHRLRKIEEIATDLKKKS"
     gene            complement(10414..10839)
                     /locus_tag="ACGI5H_001977"
     CDS             complement(10414..10839)
                     /locus_tag="ACGI5H_001977"
                     /EC_number="3.6.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416968.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
                     /protein_id="HFG9697680.1"
                     /translation="MREEVSAGGVVLFGNTILLLRKFNGDWVLPKGKVEEGENNQEAA
                     LREVSEETGVKADILKYLGEIHYTFKENWDENRAVHKTVFWYLMQAKNMDTIPQKEEG
                     FIDAKFIHLDRVVDLARYDDEKEIIKVALQEIKKRLKKN"
     gene            complement(10908..12014)
                     /gene="yvcK"
                     /locus_tag="ACGI5H_001978"
     CDS             complement(10908..12014)
                     /gene="yvcK"
                     /locus_tag="ACGI5H_001978"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891913.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uridine diphosphate-N-acetylglucosamine-binding
                     protein YvcK"
                     /protein_id="HFG9697681.1"
                     /translation="MAKLLIIVGILGWIALIVSLFIYKKAKNEKVKLFQRSIVENREP
                     NVVVIGGGTGQSVFLRGLKHTTQNITAIVTVADDGGGSGVLREDLGMLPPGDIRNCLL
                     ALANIEPTMNEVMQYRFTEGLLKGQSFGNLFLAAMNGLYGNFEKAVYKLSEIFAITGR
                     VLPVTLEDVNLVAKLENGNIINGESSIPEESKIQKSSIDKIFLNPKDVKPLKDVIASI
                     YDADIIIMGPGSLYTSIIPNLLVEGIVDAIKSSVAPKVYIANIMTQPGETEGYNVLEH
                     VNAIVKHTDENLIDYVIANNEILPEEMLDLYKQDGAEQVLLDKKQKDKLKEMGIKTVE
                     KNLIEIKNNYIRHDAKYISNIVIELALNHNYNKS"
     gene            complement(12026..12883)
                     /gene="rapZ"
                     /locus_tag="ACGI5H_001979"
     CDS             complement(12026..12883)
                     /gene="rapZ"
                     /locus_tag="ACGI5H_001979"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429119.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="RNase adapter RapZ"
                     /protein_id="HFG9697682.1"
                     /translation="MKFVIVTGLSGSGKSETMRALEDMGFYCVDNLPPALITKFAELC
                     YQPNSSIDKVALGIDIRGRKFFEALHESLNYLEKENYEYEMVYLDCNDDVLLKRYKMT
                     RRNHPLAKDMQIPEGIKMERKIMEPLKELSTCIIDTTNMKPKDLKEEIKKIYSSGEDN
                     PNLTISVVSFGFKHGILADADLVFDVRFLPNPYYVEELRAKTGDDKEVRDYVMNSKIS
                     EEFYVKLLDMIHFLVPQYIEEGKQHLVIGVGCTGGRHRSVTITNLIAEDLSNKGYRVV
                     KKHRDSMLR"
     gene            complement(12914..13627)
                     /locus_tag="ACGI5H_001980"
     CDS             complement(12914..13627)
                     /locus_tag="ACGI5H_001980"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429113.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003824 - catalytic activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PHP domain-containing protein"
                     /protein_id="HFG9697683.1"
                     /translation="MKILADYHTHTLYSHGKGTIEDNVKVAISKGIKTIGISDHSYKH
                     IAYGVKKKDILKMREEVDYLNDKYTDINILLGMECNILDDKGNIDMDDKFIRDFDYIM
                     AGYHFGSTPTSLRSLLNHCNNYIFKTEKAKEYNTKAVINAISNNDIFIITHPGDKGDV
                     YIEEVAKTAKKTNTRLEINSSHSFLNVNQLNKIKGLENKFIIGSDAHCPERVGDFELA
                     MKTISDSNLDISLVENIII"
     gene            complement(13631..14545)
                     /gene="murB"
                     /locus_tag="ACGI5H_001981"
     CDS             complement(13631..14545)
                     /gene="murB"
                     /locus_tag="ACGI5H_001981"
                     /EC_number="1.3.1.98"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009906469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008762 - UDP-N-acetylmuramate
                     dehydrogenase activity [Evidence IEA];
                     GO_function: GO:0071949 - FAD binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramate dehydrogenase"
                     /protein_id="HFG9697684.1"
                     /translation="MNNQDIYINLLNILSKEDIKVDEPMKKHISFRVGGPADILVRPR
                     TEEQLKNVLKLVKKESIPYLIIGNGSNILIKDGGIRGVVIELADNFNSYEINDTRMTA
                     QSGALLSVLGKALQKQELKGFEFASGIPGTLGGALAMNAGAYGGEMKDIVKSVRLMDM
                     EGNIFELSNEQMEFGYRKSIISKNGYIALSAELELQEGNYDEIKSLMDDLATRRITKQ
                     PLNFASAGSTFKRPTGYFAGKLIEETGLRGLTLRGAQVSEKHCGFVVNQGEASAKDIL
                     DLIYVIKSAVYAKFGVMLEEEVKILGED"
     gene            complement(14818..15588)
                     /locus_tag="ACGI5H_001982"
     CDS             complement(14818..15588)
                     /locus_tag="ACGI5H_001982"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416955.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_function: GO:0015499 - formate transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0015724 - formate transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="formate/nitrite transporter family protein"
                     /protein_id="HFG9697685.1"
                     /translation="MSKGFLTPGETAQATISAGIKKANISTQNAILLGLFGGAFIGFG
                     ALGSMIVSQTFGKIDPGVASFLSAMVFPVGLMLVVVAGAELFTGNTLMAIALMDKKIT
                     LGKMLRNWGLVYFANLVGSILLVALVFYSSTLTGDAATKAIAVAEAKVNSTIASMFLK
                     AILCNILVVLAVWMATASQDIMSKLASCWTVIMLFVLCGFQHSVANMFFIPMGMALGA
                     NITMVQFITNLVFVTLGNIVGGSIVVGGIYYLCYVKNS"
     gene            15906..17387
                     /gene="cls"
                     /locus_tag="ACGI5H_001983"
     CDS             15906..17387
                     /gene="cls"
                     /locus_tag="ACGI5H_001983"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429110.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008808 - cardiolipin synthase activity
                     [Evidence IEA];
                     GO_function: GO:0016780 - phosphotransferase activity, for
                     other substituted phosphate groups [Evidence IEA];
                     GO_process: GO:0032049 - cardiolipin biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cardiolipin synthase"
                     /protein_id="HFG9697686.1"
                     /translation="MFDISFFEMSIYEIAVTTIYIINFMVILNLIFREKRNINTTLTW
                     LLILVLIPALGFILYIAFGRNISKNNMFRLKEKDDKIIKSNILDTQVKLQSTSEIDSD
                     IHQHKDMIYALANSNNAHYTNNNDVWIYAESSQFFNSLLEELKKAKKYINIQFYIFKD
                     DKIGTEIIDILIDKAKEGVEVRLLFDAVGGRTLKNSTLSRLKESGVKVGSFFPSFLKI
                     VNFNLNYRNHRKIVVIDGKVGFVGGYNVGDEYLGRNPKFGLWRDTHTKLTGDCVIDLN
                     MRFILDWRYTTKEDLDLEKYFIEEDTNSNHPSENIGIQIVSSGPDISELDEIKYGYLK
                     MIQKARKYIYIQSPYLILDSTFIDTLKIACLSGVDVRVMIPSKPDHPFVYWASYSYAG
                     ELLKFGAKIYTYGQNAFLHAKTIVIDDSICSIGTANMDIRSFELNFEVNAFMYSSKKA
                     LEQRIIFENDILNSKEITLDIYNSRSTYIKIKESISRLLSAVL"
     gene            17705..18202
                     /locus_tag="ACGI5H_001984"
     CDS             17705..18202
                     /locus_tag="ACGI5H_001984"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891918.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent oxidoreductase subunit E"
                     /protein_id="HFG9697687.1"
                     /translation="MCDFISHNKQLFDELDIFIDSLATKEGALIQVLHEAQGIFGYLP
                     KEVQLHVARKLGVAPAKVYGVVTFYSYFTTEPVGKYKISVCLGTVCFVKGADKILSAF
                     EKQLGIKVGETTSDFKFSLEGLRCLGACGLAPVVTVNGKVYGKVKPDQVSEILDTYRE
                     LELNC"
     gene            18219..20105
                     /locus_tag="ACGI5H_001985"
     CDS             18219..20105
                     /locus_tag="ACGI5H_001985"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416938.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0051539 - 4 iron, 4 sulfur cluster binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NADH-ubiquinone oxidoreductase-F iron-sulfur
                     binding region domain-containing protein"
                     /protein_id="HFG9697688.1"
                     /translation="MRKVNSFDELKVLADELKPNLSLRKNYSKENVLRRELLVCCDTG
                     CTSSNSLEIVSELENEIKKSGIQDKVSVRLTGCFGFCAQGPIVKVYPDNVFYVKVEPS
                     DAEKIVQSHLIRNTVVEELLYEEESLSKKVEEQEEMSFYKKQLRIALKNCGLIDPDSI
                     EEYIANDGYLALGKCLTSLTPQEVIAEVKTSGLRGRGGAGFPTGSKWEAASKNPAGPT
                     DKKFVVCNADEGDPGAFMDRSVLEGDPHSVLEAMAICGYAIGSDTGYIYIRAEYPKSI
                     ERLKVAIAQAEKYGLLGENILGTGFNFKLELKYGAGAFVCGEGTALMHSIEGRRGEPR
                     MKTYSSSKSGLWKSPTCLNNVETFANIPAIILKGGDWFANLGTEDSSGTKVFALGGKV
                     ENVGLVEVPMGTTLRDIVFEIGGGIPEGKKFKAVQTGGPSGGCIPTEHLDTPIDFGSL
                     SSIGSMMGSGGMLVLDESDCMVDIAKFFLEFTVEESCGKCTPCRIGTTRLLEILTKIT
                     EGNGTLQDLDDLENLAETIQTASLCGLGKAAPNPVLSTLQYFKDEYIAHVVDKKCPAG
                     KCQNLLSYFITDDCKGCTKCSRVCPAGCITGSVKEQHTIDTSKCLKCGACIDNCTFNA
                     IIKK"
     gene            20128..21909
                     /locus_tag="ACGI5H_001986"
     CDS             20128..21909
                     /locus_tag="ACGI5H_001986"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429109.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADH-dependent [FeFe] hydrogenase, group A6"
                     /protein_id="HFG9697689.1"
                     /translation="MSLVNLTINGKHVSAPSGTSILDAAKLINIKIHNLCHLHMNEID
                     KLDTCASCRVCMVETERGLVPACGTVIKEGMKVQTNSAKALNARRTIVELLLSDHPQD
                     CFVCEKNGDCELQTIAADLGVRKIRYQGSKSFAGKDTSTKSLVKDHSKCILCRRCETV
                     CNDIQTVGALSGVNRGFNTLVSTFFNSDMVETECTFCGQCISVCPTGALTEVDNVPKL
                     WDVLNKKEKTIVVQVAPAVRVAIGEEFGLEPGSISTGKMVAALKALGFEHVFDTNFGA
                     DFTIMEEATEFIERIQKGENLPILTSCCPAWVNFLEHNYPDKLNLASSCKSPQGMFGS
                     IAKNYYAPKILGINPEELYVVSVMPCVAKKYEASREELSESGILDVDLSITTRELAKM
                     IKEAAIDLPNLQDQDFDNPLGKSTGAASIFGASGGVLEAALRTSYEKITNKTLDNVNF
                     TNVRGLKGIREASIDVDGTTVNVCIVNTLKNARKIMDKVRSGECKYHIIEVMACPGGC
                     VGGAGQPYHHGNTEIVDRRANALYEIDRNKAIRKSHENPDLQAIYKDFFGEPNSDVAH
                     KYLHTHYFDKSCVYGECPQECACEEAK"
     gene            complement(22049..23845)
                     /locus_tag="ACGI5H_001987"
     CDS             complement(22049..23845)
                     /locus_tag="ACGI5H_001987"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903750.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mannonate oxidoreductase"
                     /protein_id="HFG9697690.1"
                     /translation="MGIEYFSKLLESSTEKELLLSKKSNNISTARLISFLIVIAGLAI
                     GFYNKNIVGIFVGVLSIIIFIALLVIHSKVKEEETYFKSKSEVLNKYIKRFGDGWKEF
                     KIDGKEYLKDENSQAKDLDLFGRASLYQYICVANTSYGKNFLAKYLWNENPDENIILE
                     RQRAIKELLSKDDFSIHIQTLSNIIGKEQKNNSDSSIESFIEYGENKNVYIPKWMHIF
                     TWGLPTATILSFIFCMLGFLPVLPVFLLFIIQLGFSGFGYPRLMQTLAPLFSFSRSIQ
                     VYEKMFEVLEKETFESAYLKELQDKLSKGSGVSRGVKQLNSIGNAVNLRYNQILYIIA
                     CGVLMWNYHCAEALERWKGIYGNQIRDWFESIGEFEALISLTVVSHVKENTCFPVIKY
                     EDTPRLKVEEVYHPLIAEKSVIANSIQLNSQTCIITGSNMSGKTTFLRSIGVNLVLAY
                     AGAPVCAKSFDATCMAIFTSMRIQDDVSQGISTFYAEILRIKSMIQYSLKELPMLVLV
                     DEIFKGTNSADRIIGASEAVKKLSKPWVISMVTTHDFELCDLSGSGDVEVVNYHFSEY
                     YVDDKIHFDYKIKDGRCKTTNAKQLMRMAGIL"
     gene            complement(24057..24986)
                     /gene="hprK"
                     /locus_tag="ACGI5H_001988"
     CDS             complement(24057..24986)
                     /gene="hprK"
                     /locus_tag="ACGI5H_001988"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416935.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000155 - phosphorelay sensor kinase
                     activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA];
                     GO_process: GO:0006109 - regulation of carbohydrate
                     metabolic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="HPr(Ser) kinase/phosphatase"
                     /protein_id="HFG9697691.1"
                     /translation="METSNKVSIREIIKELKLKVVYMPDDVDYYVYSQDINRPGLQFA
                     GYFDYFAYERIQIVGKTEYNFFGLMDSHIREEVLDRFFSYEIPALIISRDLEIKPDVI
                     EKAKKYKRILLSTNRNTTRLINRLSNYLDNKLAPHTTIHGVLVDIYGIGVLIKGESSI
                     GKSETALELIQRGNRLVADDAVEIRKLDESMLVGQSPELIRHFLEIRGIGIIDVRSLY
                     GVGAIKNSKMIDLVVHLEAWDETKYYDRLGLDKEYEEILGVNVEKLVVPVKPGRNTAM
                     ILEVAAMNFRQRGMGYDAAQEFTKKLSKLIDTK"
     gene            complement(24986..26803)
                     /gene="uvrC"
                     /locus_tag="ACGI5H_001989"
     CDS             complement(24986..26803)
                     /gene="uvrC"
                     /locus_tag="ACGI5H_001989"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009380 - excinuclease repair complex
                     [Evidence IEA];
                     GO_function: GO:0009381 - excinuclease ABC activity
                     [Evidence IEA];
                     GO_process: GO:0006289 - nucleotide-excision repair
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="excinuclease ABC subunit UvrC"
                     /protein_id="HFG9697692.1"
                     /translation="MFDIQEHLKKLPSEPGVYLMKDKYDHIIYVGKAISLKNRVRQYF
                     QSSKNHTSKVKSMVKNIYKFEYIITDSELEALILECNLIKRYRPKYNVVLRDDKTYPY
                     IKVTTNEDYPRILKVRRVLKDKAKYFGPYTNITAVNDTLELISSTYPIRSCKIDIDKA
                     IKNKTRPCLNLHINKCLGPCTGNVSKEEYGKMIEEIIMCLSGKEEKLMELLKEKMNES
                     SMNFRFEEAAVYRDKIKSLEEMIQKQKIDATVSDLNQDVVAMARAHNEACVQVFFIRN
                     GKIVGREHFILEGVMDSPRASILSSFVKQFYNEQEYIPKELIIEDEIEDSSILEEWLS
                     SKKGQKVTIRVPQKGEKKSLVEMVRKNAVEYLEKFSDMNKRKYEKSIGALEELKQILN
                     LEKLPIRIEAYDISNIQGVDSIGSMVVYTNAKKDKKEYRRYKIKTVIGPNDYDSMAEI
                     VDRRLKHGNLPDLILLDGGKGQVSAVKKVLELNDVDIPLWGMYKDDKHRTKGLICKEK
                     EIELDKTTNLYRFIASIQEEVHNYAITYHRSLRNKALTKSILDDIQGIGEKRKKSLLN
                     HFKDVDAIKKATMEELLEVDGMNKSIADNVYNFFRKEEN"
     gene            complement(27062..29887)
                     /gene="uvrA"
                     /locus_tag="ACGI5H_001990"
     CDS             complement(27062..29887)
                     /gene="uvrA"
                     /locus_tag="ACGI5H_001990"
                     /EC_number="3.1.25.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422159.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_process: GO:0006289 - nucleotide-excision repair
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="excinuclease ABC subunit UvrA"
                     /protein_id="HFG9697693.1"
                     /translation="MEDKIIIRGAKEHNLKNIDLELPRDKFIVFTGLSGSGKSSLAFD
                     TIYAEGQRRYVESLSAYARQFLGQMEKPNVEYIEGLSPAISIDQKTTSKNPRSTVGTV
                     TEIYDYLRLLFARVGDVYCPTCGEKISQMTIQEIVDKMLDFPDRTKLQILSPIVRGQK
                     GTHKKVFDNIKKEGFVRVRVNGENYEVSDDIILNKNQKHNIEVVVDRIVIKDGIESRL
                     ADSIETAVKLSDGLVIAQIIDGEEILFSTKFACPEHGIGIEELSPRMFSFNAPFGACD
                     VCNGLGESKEVDPELVVPNKDLSIKQGAVAAWGSTGVNDDTYYSKMIKSLAEHFNVSL
                     TTPFKDLPDDFVEELLYGKDNIIVEFTYESKFGGTRNYKSYFEGVIVNLERRYRETNS
                     DYMRDKIEEYMAERPCPKCKGMRLKKEVLSVLVDGKNIMEVTNLSVNELIDFMENINL
                     TEKQRFIAHEIIKEIKGRAMFLRDVGLDYLNLSRKAGTLSGGEAQRIRLATQIGSALV
                     GVLYVLDEPSIGLHQRDNDRLITTLRHLTDLGNTLIVVEHDEDTMREADYVIDIGPGA
                     GIHGGEIVAQGTLDEIIENENSITGQYLSGKKQILLPETTREGNGSFIEIVKASENNL
                     KNIDVKFPLGKFTCITGVSGSGKSTLINDILYKGVASKVNRLKQRAGKHKEIKGIESI
                     DKVINIDQSPIGRTPRSNPATYTGVFDFIRDIFASTNEAKARGYKKGRFSFNVKGGRC
                     EACKGDGIIKIEMHFLPDVYVPCEICKGERYNRETLQVKYKDKTISDILDMNVEEAVE
                     FFENIPNIKRKLETLMDVGLSYIKLGQPSTQLSGGEAQRIKLAAELSKRPTGKTLYIL
                     DEPTTGLHMADVDKLIQVLQRLADTGNTIIVIEHNLDVIKTCDYVIDLGPEGGDKGGT
                     IVATGTPKEVSKVDGSYTGQFLKKYFS"
     gene            complement(29906..31876)
                     /gene="uvrB"
                     /locus_tag="ACGI5H_001991"
     CDS             complement(29906..31876)
                     /gene="uvrB"
                     /locus_tag="ACGI5H_001991"
                     /EC_number="3.1.25.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728494.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009380 - excinuclease repair complex
                     [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0005515 - protein binding [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_process: GO:0006289 - nucleotide-excision repair
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="excinuclease ABC subunit UvrB"
                     /protein_id="HFG9697694.1"
                     /translation="MDFKIKSDFKPTGDQPEAIKSIVDSINRNEKFSTLLGVTGSGKT
                     FTMANIIQQVKKPTLIMAHNKTLAAQLYSEFKEFFPDNAVEYFVSYYDYYQPEAYVAH
                     SDTYIEKDASINDEIDKLRHSATASILERRDTIIISSVSCIYGLGDPKDYKELMLSIR
                     PGMQRDRDDVIKRLIEIQYERNDINFTRGTFRVRGDILEIFPASNDEKAIRIEFFGDE
                     VDRITEIDYVTGKIVGTRNHVVIFPASHYVTTPERIEKAIVEIENELQEQIKFFKEND
                     RLLEAQRIEQRTKYDIEMLKEIGFCQGIENYSRHITGRSEGERPYTLMDFFPDDYLII
                     VDEAHVTIPQVRGMYAGDRSRKTSLIENGFRLPSALDNRPLNFQEFEGNINQMLFVSA
                     TPGPYEIQHSETIAEQIIRPTGLLDPIVEVRPINNQIDDLVGEITKTIEKNERVLITT
                     LTKKMSEDLTNYLKEIGIKVKYLHSDIVTLERTEIIRDLRLGKFDVLVGINLLREGLD
                     IPEVSLIAILDADKEGFLRSETALIQTIGRAARNENGRVIMYADRITDSMQNAIDETK
                     RRRDIQNLYNEEHNIIPKTIQKNIRDSIEATKVAEEEVVYGISDTDDKDEIRANIDKL
                     KSEMMEAAQNLQFERAAELRDKVKQLEEKLEK"
     gene            complement(32063..33325)
                     /locus_tag="ACGI5H_001992"
     CDS             complement(32063..33325)
                     /locus_tag="ACGI5H_001992"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903752.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alkaline phosphatase family protein"
                     /protein_id="HFG9697695.1"
                     /translation="MTKVIVLSVDSLFEKDLEFVKNLPNFKSILENCSIVKNINCVYP
                     TLTYPCHTSMVTGVYPKKHGIYHNEKFDPNKENKDWYWYSKDIKAKTIIDVAKENNLT
                     TSSVLWPVMGANPNIDYNIAEIWAPSREDDPRETFERSSSKVIMDGIYNRHCHYIDWK
                     LEPNMDLFGVNCSVDIIKEYKPDLMLIHLATLDHTRHNYGLFNDEVDKALKMNDKWLG
                     DIIQATKDAGTYKDTNFIILGDHGHLRVDKVINPNVLLKSNGFIKVENGEVKDFDAYV
                     NSSGISAQIIVNNLDRLTELRELLEEFKEELFIENIFTKEEASNLGLEGDFEMVIEGL
                     EGISFGNDFEGSIIKDSDIKDYKFAVATHGHLPTKGNRPPFIAFGPNIKGGVVIEEGD
                     LRAHAATILKMFNLKLDGVEKEAFDFIM"
     gene            complement(33388..34692)
                     /locus_tag="ACGI5H_001993"
     CDS             complement(33388..34692)
                     /locus_tag="ACGI5H_001993"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891939.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HFG9697696.1"
                     /translation="MKLKRKLATGLAITLLLCSLVGCSNSNDANASKGEKTDSNITKI
                     DFWAPLGGTNGETAQKMVDQFNSEHKDVQVNMLKQKDYYENATKLQAALTSKDQPDVT
                     LLEITQTGTFASAGALVDMSKYFDKTYQERFFSGLLTNSYYEDKFVGMPFNRSTPILY
                     INKDMATKAGLDPSGPKSWEELKDYASKMTNKSEDTYGFETPIDIWFYEAMVMQSGGE
                     ITNGKKVAFNNEAGQAPVKFWQDMMKAGIMKMPPGEDYNAWDVAKQDFVNGKVGMIFT
                     STADLAGLMQQTEGKFEISTAFLPKNQKYATPTGGANLVMLEGGTDKEKEASAEFIEW
                     MTQTDKIVQFSSSTGYLPTTEDATNSEKLQTLYKEKPQYKVATDQLQYAVALPMLNGY
                     KEATDKLMDEIKKGLTDLNANPKDVVSKGTSAMQAVIDKTNK"
     gene            complement(34723..35583)
                     /locus_tag="ACGI5H_001994"
     CDS             complement(34723..35583)
                     /locus_tag="ACGI5H_001994"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891940.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HFG9697697.1"
                     /translation="MDIIQPIKKDKVDIKKIASKSIEILILLLLSAIFIFPFIWMLST
                     SFKNPQEMMQLPPTIIPNDIVLENYSTAWHSGPFFRYLLNSVFVTGSVLIVQFLVMVP
                     AAYAFSKIKFKGEKMLFGLLLVGLMIPPQVTFLPVYMMMSKFGFINTYVPLIIPFMTS
                     SFGIFLLRQNFMQISDEIIEAAKLDNASDLKIMFRIMVPMAKPAVITFILFNFIYHWN
                     NYFWPLVMTNTDAIRTLPIGVALLKSSEGITAWNVIMAGNIILILPIILVYIFANKKV
                     KEAFMYSGIK"
     gene            complement(35627..36496)
                     /locus_tag="ACGI5H_001995"
     CDS             complement(35627..36496)
                     /locus_tag="ACGI5H_001995"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429101.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HFG9697698.1"
                     /translation="MKKQFNKAYLYITPAIIGTLLFIVYPIIKTISLSFKSGSLLSST
                     FENVGLNNYTELLKNPEFIQTITNTAIYTFFMVTISISLAIVLAVWLNKNSIIHNLTQ
                     SIIFTPHVISLVSVAVLWLWIMEPQYGFLNWILSTLHLPTSKWLSSESSALMSLILIG
                     IWKTLGYNILIVLSGLKSIPNYIYEASKLDNANKITNFFKVTLPLLSPTIFFLMITTT
                     TASFQVFDEISIMTQGGPVGSTNMLSYYIYESGFIYYDIGQASAASMFLLAIVMIATY
                     ANFRLLSKKVHYQ"
     gene            complement(36480..37550)
                     /locus_tag="ACGI5H_001996"
     CDS             complement(36480..37550)
                     /locus_tag="ACGI5H_001996"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429100.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HFG9697699.1"
                     /translation="MADIRLENVTKSYNKKNTVIENLNLTIEDGSFTVLVGPSGCGKS
                     TTLRMIAGLEDITSGRLKIEENDVTKTDASKRDIAMVFQNYALYPHMTVRENIEFGLK
                     NKKVEKEKREKLITEVIDVVGLREYLNVKPGNLSGGQRQRVALARAMVKNPKVFLMDE
                     PLSNLDAKLRNQMRTELIQLHQKLKSTFVYVTHDQVEAMSMADKIVIMNKGKIMQIGS
                     PKKIYQNPKNLFVAQFIGSPCMNILDIKNDIKFGFRPEKATLESINIDGKNDDVFSLF
                     GKVVTKEVLGNETIYCLSVLNREIRVKTENDIFDIGRTLRISVLEKDLYYFDKNGERI
                     EDVKVCKSMYSKIKGDIYEKAI"
BASE COUNT        11842 a         6700 c         4690 g        14761 t
ORIGIN      
        1 cttattcttt tataactttt aattttaaaa gaggagaatg tatataagag tattcaatgt
       61 actagaaaaa atcaaaagaa atattagaag aaatggatat tgagtaatca aagaaaagat
      121 tttgatatta caaatgatat gtttcaagaa agcattccta tcacaacaaa aattattctt
      181 gaagacatgc cttcaaatga tgaattaaat catgtttttt caaaaggttg tgaacgaaaa
      241 atgaaaaaga gaaaaattgt attaatcaca ctactattaa taggtgtttt gttattagga
      301 agtatcctat ataatctttt tttaggaaaa acagctaata tttcaatgct aaaggaatct
      361 tggaattttg atataccaat acctaacaaa gaaattgaag tatttgatac tcaagatagt
      421 attaatggag atggacaaag ttattttatt caaggatttt ctgaaaaaaa tttcaaaaaa
      481 gtttttaatt taaaaggtgg tatagttgta agcaaagata atattaatga aatagaaaaa
      541 tatattgata aatttaaaag agattctgtt aacattaata aaagtaataa aaataaaatt
      601 gaagaagatt ttaaaaaata taagttagaa gttaaaaaag atgataagta tatatataag
      661 agaaattatg agaactacgt agttttaatt ataaaaaaag atgaacaaaa attatacagt
      721 ttaatatgga atcagtaggt acatatgtat tattaagaat tataaataat aaaaataaat
      781 tttagtcaat atacaaaaac cttttaaatt gtctggaaat cacctcttca tttgttataa
      841 aaacatacaa caaatgaaga ggtgatttta tggttttaaa aaaaataatt ataagtggat
      901 atgtgctttc acatgtttat caacatttgt aatgcctata tttgctaatg aattataaaa
      961 atattaaata atattcaact atagattatg taaattactc tatgaaaaaa atgagttgta
     1021 taaaatctgg ctactgtaga ttgactattt cttttaaaat tacaattata ataagtttta
     1081 tagaattaaa aataaaactt tagagatttt tgataacatt gtagactaaa tttgccaccg
     1141 aaatcgcttt acagtggcaa atcggtggca aatacaatat attattagta tataatctat
     1201 ataaacatta ctattgtttg attatcttag ctacagtttc cacatgtgta gaatgaggga
     1261 acatatctac aggttgtgcc tcaacacatt taaatccgtg aacatttaga taatctaaat
     1321 cccttgctaa agtagaagga ttacaagaaa catagacaat tctttccgga ttcattgaaa
     1381 caatagtctc taataccttt tcgtcacatc cctttctagg tgggtctaca acgactacat
     1441 tggcagtctt accctctcta tacatcttag gtacaatttc ctctgccttt ccaacataaa
     1501 attcagcatt atgtatattg tttaatttag catttatctt agcatctttt atggcatcat
     1561 ctataatttc tattccataa acctttttag ccttttgtgc caaaaataaa gatattgtac
     1621 ctatcccaca gtaaatatca aaaacagtat cagtatcatt taaatttgca tattcaagag
     1681 ccttatcata caatacttta gtttggacag ggtttacttg gaaaaatgat aatggtgaaa
     1741 tctcaaacac taagtctcct atataatcgt ttatttttcc atctccatat ataactatat
     1801 tttctcttcc tagaatagca ttcgtatctt tttgatttac atttacaacc aaagtcttaa
     1861 atccaggtat attttcctta agcactgaag ctaattcttt aagatatgga agtttgtttc
     1921 catttgctac taatacaacc attacttctt tagttgtaaa acctattttt gttactaaat
     1981 gcctaatcaa ccccgtgtga gtcttttcat catatatgct taccttatag gcccttatat
     2041 atgtttttat tattttaaca attttatcat ttatctcatg ttgtattacg catttttctg
     2101 tcgatattac atcatgagtc ttctttttat agaagccaat aattggaata ccattattct
     2161 tttgtattgg aaattgtgct ttatttctat atctatatgg attatccatt cctatagtgt
     2221 catgaacttc tacatcctct aacttaccta ttctcgaaag tacttgttta acttcatttg
     2281 ttttcatttc aagttgttta ttataatcta agtcttgtat ctgacaccct ccacaatccc
     2341 taagattgtc actacacact cttttcaccc tgaatggaga cttttctatt atctcaacaa
     2401 tatctcccac agcataattt ttctttactt tattaatcct aactttaact ttatcatgta
     2461 ttaatccgcc ctctacaaaa actgtaatac cattgtactt tcctactcct actccgcctt
     2521 gaccaatgtc tactatatct acaatataca tctcgttttt cgaaagcata aatcaccctc
     2581 caatcaatct attatattta aatctttaca aacttttttc tttaaattta tattaaaata
     2641 ttgctattaa ttaaactata ttttttacta agctacaata ttttatttta ccaaaaaaaa
     2701 aggagcttat aaagcccctt agtaaataaa tttattattt ttcttataaa actctagttg
     2761 aacctctata taccacgcct cttgatgcat ccacagttac aacttctcca tcttttacta
     2821 gatttgttat atcagctgca gacacaataa ctggtatatc taaatttata cctacaatag
     2881 ctgtatgtga tgtcattcca ccattctcag ttactacagc tcctgctttt tctatataat
     2941 tgttcatttc agcatcagta gcagtagaaa caagtatgtc gccttcatta aagtctacac
     3001 aagcatttcc attctttatt atacgaactt taccttctac tgtttgagta cctacaccta
     3061 taccttgcac gatttcttcg cttattacat gaacctttat taaattagta gttccactta
     3121 ctcctactgg tactccagca gttataacta ctaattcccc attatctata taatcagctt
     3181 gtctagctgc ctcaattgcc ttttctataa cttcatctgt atttcctgca acagaagact
     3241 taactggata tactccccat gtaagagcta atttattcat agtcttttca ttatttgtag
     3301 tagctattat tggagatttt ggtctgaatt tagataccat tctagcagta tatcctgaag
     3361 aagtagatgt tattatagct gatgcattta aatctactgc tgttgtacaa gttgcatggc
     3421 ttattgcatc tgttacagta acattgttag taccattttc ctttagtaat ctatcataat
     3481 ctaaagtctc ttctgttctt tttgctattg tagccatcat ttttactgcc tctacaggat
     3541 attttccagc agcagtttct ccagataaca ttatcgcatc tgttccatca tatatagcat
     3601 tggcaacgtc tgtaacttct gctcttgttg gtcttggatt tcttatcata gaatcaagca
     3661 tttgagtggc agtaacaact ggctttgcta attcattaca tttttttatc atcatttttt
     3721 gaactattgg catctcttca gttggtatct caacacctaa gtcacctcta gccaccatta
     3781 taccatcaga aacttttaat atttcatcta ggttctctac accttcttgg ttttctattt
     3841 tagatattat ttgtatatca gttgcattat tgttctctaa tacttctctt attgctagta
     3901 catcagatgc ctttcttaca aaagaagcag ctatataatc tattccttga cttattccaa
     3961 actctatatc acttatatct ttaggagtta ttgctggtaa atttatctta acaccaggta
     4021 catttactcc tttatgattt ttaactattc ctgaattttc aacaacacaa actatatctt
     4081 ctccatttat ttcttttact cttaagccaa ctaaaccatc atctattagt atagaatctc
     4141 ctgatttaac gtcttcagca agacctttat agcttactgt acacatttct ttagtcccca
     4201 taatatcttt catagttata gtgaactttt gcccttcttc taaaaatacc tctgggtctt
     4261 caaagttacc tgttctaatt tctggacctt tagtatctaa taatatagca actggcttat
     4321 ttaatttttc tctaactttc tttgccatat caattctttc tttatgttct tcatgcgaac
     4381 cgtgagaaaa gttaaatcta cacacattta gaccattttg cataagttga gttaaaactt
     4441 cctcactttg tgatgctgga cctagtgtac aaacaatttt tgtcttcttt acattattta
     4501 acatatttgc tcctcctgag atattattcc acagatttat ttttaatact aaaacttata
     4561 tagataatat ttttgccatc tcataagctt ctttatcaaa tactttcttt tgagctaaag
     4621 cttcacttat ttctaaatca attattttgt tttcttttat tcctacaact ctagctgatt
     4681 ttccatctaa taataattct actgctctta ctccaagtct acttgctagt attctatcag
     4741 atacagttgg gcttcctcct ctttggacat gccccaatac agtgactctt aaatctgctc
     4801 ctgactcttt tttaagttcc ttttctaaat cactagcact tccgactcct tctgctaaaa
     4861 cgattatact atgtctctta cctctttttt gagtagtctt taatcttaga gcaacttcat
     4921 ctactgtaat ttctacttct ggtactatta tagtttccgc tcctcctgca agacctgcat
     4981 ataaggctaa atctccacag tgtcttccca taacttctac tatgttaact ctttcatgag
     5041 atgatgatgt atctcttatc ttacctatag catctataat agtattcatt gcagtatcaa
     5101 atcctatagt ataatctgta tatgctaaat cgttatctat agttcctggt atgcctatag
     5161 ctgggaatcc taagtcacta agtttttggg ctcctgcaaa tgaaccatct ccaccaatta
     5221 caactaagca atcaatttta tactttttaa gaatttttac tgcttttaat ctaccttctt
     5281 ctgttttaaa ttcttcacat ctggaagatt ttaatatagt tcctcccctg tgtataatat
     5341 ctccaacaga agataagttc atttcagtta aatcttcttc tagtaatccc ttatatcctc
     5401 tattgattcc atatactttg catccataat atattgctga tcttacaacc gctctaatcg
     5461 cagcattcat tcctggagca tctcctccac ttgttagtaa tcctatagtt ttcatttttt
     5521 acctccttgg attttatgtc aattttttat tataatcatt gttattgtat tctaatggac
     5581 tttttttgtc cctatatcac tttttaatcc catcaagact aaaaaaatta aatgtcctta
     5641 aatgtccatt ttgtgatatt atatcacaaa acggacaata tttttcatat tattataata
     5701 tatttagatt tttatataaa aaatcaagct tttactttta tgttatcttt aggaagtaac
     5761 tcttctaagt tatttataaa ttcatcacat atacaagtca atgccccggt cattttatat
     5821 gctttacgtt taccatttat attttcatcc atagggtata agtatatact gtcattacct
     5881 ggatattgtt tggctatttc tacaatatta ttagttgtat cagtatcaga catactatct
     5941 attttcaaat acaatttttt accactttct ggcttaatat tttctacatt tctagttctt
     6001 cctgaattgt agtttctatc tgcaaagtca gtatcatcat ttatatcttt tatctctcta
     6061 gctataagtt ttgcattttc gccttctttt atacttaatg ttccttttac atatattata
     6121 ttatcttcat tcaaaatgac attatacttt tgtaataatt gaggaaaaac tattatttct
     6181 atagcaccat acaaatcttc taattcaata aatgccataa tttcatttcg ttttgttgtt
     6241 ttaatagttt tagttacaat cattccaccc attataacat ctgtttcatt catttgtagg
     6301 tatgactctt cttcctcttt taatgaattt aattttccat tatccataga tgttttttct
     6361 tgtagttctt tttcaaattg tgataaagga tgtccactta catacattcc caagacttct
     6421 ttttcaaggt taagtctctc tctttcttcg tactcttgcc ttttaggcaa actgtatatt
     6481 tgttgaaaat cactatcttc ctcactatct ccaaaagcat caaataaaga aatttgacct
     6541 tgaacatttt tctttctatc catagataca ctttctaata aactttcata accagccatc
     6601 agactagctc tattttcact tatattatca aaagctccac attttattag actttctatt
     6661 actctcttat ttgtatcttt ttggtctaat cttttgacta aatctactaa atctacaaat
     6721 aatccattag attctctttc agcgattata ttgtttatta tatttacgcc aacatttttt
     6781 acggctgcta gaccaaatct tatattgtcg ccttcaactg aaaactttga aaaacttttg
     6841 tttatatctg gaggtaatac atctatttct agtgctttac attctcttat atactcaact
     6901 accttatcag tatttcccat tacactggtt atcaatgctg ccataaattc aactggataa
     6961 tatgttttta gataagctgt ctcatatgct aaaaccccat atgcagctgc atgtgattta
     7021 ttaaatgcat atctagcgaa gtctatcata tcatcaaata ttttattagc tatttcctct
     7081 tctacaccat ttctgataca ccctgcaatt tctatattac catcttcatc aaatttacca
     7141 tgaataaaat attgtctttc ttcttccatc acgtccatct ttttcttact catggctctt
     7201 ctaactaggt cacttcgtcc gtaactataa ccacctaaat ctctaacgac ctgcataacc
     7261 tgctcttgat ataccaaaca accatatgta acttccatta taggctttaa tttttcatgt
     7321 agatatgtta catcttttgg gttgctttta ttttttatat atgcaggtat agaatccatt
     7381 ggacctggtc taaataggga tattcccgct acaatatctt caaaattgtc tggttttagc
     7441 tgtttcataa aacttctcat gccagcactc tccaattgaa acacccctag tgtatttcct
     7501 gatgaaagca tttcatatac tttcgggtcg tcataatcca tctttgaaaa gtctattttt
     7561 tctgtgtaat tttttataac tctatttttt tctattaaat caagagtatc tcttataact
     7621 gtaagagttc ttagcccaag aaaatccatc tttaaaagcc caagttcttc aagtgttgtc
     7681 atagtaaact gtgttgtgat tgcatcttga tgtttgtaca aaggtacata ttcatctacg
     7741 ggattttttg atataacaac tcctgctgca tgagtagaag catgtcttag cattccctct
     7801 atctgttttg atatatttat tatttctttt gtttccgggt cttggtcata caattcttta
     7861 agattaggat ttgtatctag ggccttatct attgtcattc ctaaagcaaa tggtatttcc
     7921 ttggctacct tgtcaacttt attgtagcct atatccaata cccttccaac atctcttatt
     7981 gcagcttttg cacccattgt tccaaaagtt attatctggg ctacatggtc atcaccatat
     8041 tttctcttta cataatctat aacttcttct cttctctcat aacaaaaatc tatatctata
     8101 tctggcatgg atatacgttc tggatttaaa aaacgctcaa ataatagaga gtactttatt
     8161 gggtctatat cagttatttt aagtgtatat gctactatcg aaccagccgc actacctcta
     8221 cctggtccta ctataatatt attttcttta gaaaaattta taaaatccca aacaattaaa
     8281 aaatactcta cataacccat tttttcaatt acatctaatt cataatttaa tctctctagt
     8341 atctcattac taggattatc atatctctct tttaatccat taaaacacaa ctcccttaaa
     8401 taagtttctg gtgtatatcc ttctggaaca tcatacttag gaagatgtat agtattaaaa
     8461 tcaaactcca cattacacat atcagctatt ttcacagtat tgtcaatagc ctctaatgca
     8521 tatggaaata attcttccat ttcttctctt gattttaaat aaaactcatc actaccaaat
     8581 ctcattctat ttgggtcatt taatgttttt cccatttgaa tacacataag tacatcatgt
     8641 attttcgaat cttctttatt tacatagtga acatcattag tagcaactag tggtatacca
     8701 gtctcttttg ataattttac taaaccagag tttacttctt tttgctcagg taaattgtga
     8761 tcttgaatct ccaaaaagaa attttcttct ccaaatatgt ctctgtagtc aagagcaaat
     8821 tgttttgctt tttcataatt tctattcatt aaagcacgtg ctacatctcc tgcaaggcat
     8881 gcagaaagtg ctataatccc tttgttatgt tttttaagtt cttccatgtc aactctaggc
     8941 ttatagtaaa aaccttctac gtatgaagtt gaaactattt ttattaaatt tttatatcct
     9001 tccatattct tagctaacag aactaaatgt ccttgatatt tgtcatagtt tgggtcttta
     9061 tctctcaatc cacgtgcagc tgtatagact tcacacccta taattggctt tattccttct
     9121 tttatagctg ttttgtagaa atctataaca ccaaacatac aaccatggtc agttatagct
     9181 attgagctca tgtttagttc cttagccctt tttataagtt ttttcaccct cgaaaaccca
     9241 tcaagtaaac tatactcagt atgtacatga agatgagcaa aatctttgtt cattaaatca
     9301 cctcctgctt tataatttta attttaccac aaatatatgt cctaaaacaa aaacagagac
     9361 ttttatctca aaataggaat taacttcaac gtataccatt atatgttata aattaatgct
     9421 tattctgaga ttgtcccctc aatttattgc tatgattttt ttttcaaatc tgttgcaatt
     9481 tcttctattt ttctaagtct atgattgact ccagattttc ctattggtgg ttctaacatc
     9541 tctccaagtt ctttgagagt catatcctca tactcgattc taatcttagc tatctcttgt
     9601 aaattttctg gcaaactgct aattcctata gtctcttgta tgagcttaat attttctact
     9661 tgtcttactg ctgcatttac tgttttagaa aggttagctg tctcacaatt tactatcctg
     9721 tttacattat ttctcatttc ttttactatt ttagtatttt gaagacttaa aagagcgtgg
     9781 tgtcctccta taatactcaa caaatctgat atttgttcac tctctttgat ataaacaacg
     9841 tgattatttt ttctagccac aattttacta ttaaaaccta aagagtttat aagttctttt
     9901 agagaatctg caaactcctc attattagtt acaaattcca tatgatagtt cttttctggg
     9961 tcgcttatag aacctccacc aagaaaagct cctcttatga aagctctctt acatccttca
    10021 tgcttaatta agttctctga aattttgttt atagtaaaaa atccttcttt atcttcaagt
    10081 atacctaact tttttaataa catttctgaa cccatttcgc ttgttaccat taatacataa
    10141 ctgttatttc tctttagcat ttgattctta tttactgaga ttgtagtatt gatattaaaa
    10201 ttctttttta ataatttaaa tactttacgg gctattgaat ttaactctgt tgttatcttt
    10261 agatttagct tcttatatcc aacaatttgt atacttcccc ctgatttaac tagagctgac
    10321 aattcagcta tattacaaca ttcattccca gatataactc ttgctagttc atttttggtt
    10381 tcagttgaaa aagacatatc tatcacctat taactaattt ttctttaacc ttttttttat
    10441 ttcttgtaag gcaaccttta ttatctcctt ttcatcatca tacctagcta agtctactac
    10501 tctatctagg tggataaatt tagcatcaat aaagccttcc tctttttgtg gaatagtatc
    10561 catattcttt gcttgcatca aataccaaaa aactgtttta tgaactgctc tattttcatc
    10621 ccagttttct ttgaatgtat agtgtatttc acctaaatat ttcaatatat ctgcttttac
    10681 tccagtttct tcacttactt cacgtaatgc tgcctcttgg ttattttccc cttcttctac
    10741 ttttcccttg ggtaacaccc aatctccatt gaacttcctt agtaaaagaa tcgtattgcc
    10801 aaacaggact acaccaccag cactaacctc ttctctcatc gatgttcact ccttaaaact
    10861 aacataatga taaggatttc tacacaattt tttaaaatcc ttttttacta acttttgttg
    10921 taattatgat ttagggctaa ctcaataact atgttagata tatactttgc atcatgtctt
    10981 atataattat tttttatttc aattaaattc ttctctacag tttttatacc catctctttt
    11041 aatttatctt tttgcttttt atctaacaag acttgctctg ctccatcttg tttatataag
    11101 tcaagcattt cttctggcaa tatctcatta tttgcgatta cataatctat taaattctca
    11161 tcagtgtgtt ttactatagc attaacatgc tctaatacat tgtacccttc tgtctcacct
    11221 ggttgagtca ttatatttgc tatatatact tttggagcta cagacgattt aatagcgtct
    11281 acaatcccct ctacaagtaa atttggtatt atacttgtat ataaacttcc aggacccata
    11341 attataatgt cagcatcata aatagatgca ataacatcct ttaatggttt tacatctttt
    11401 ggatttaaaa aaattttatc aatagagctt ttttgaattt ttgactcttc aggtatacta
    11461 gattctccat ttattatatt gccattttct aatttggcaa ctaaatttac atcttccaaa
    11521 gttactggta aaactcttcc tgttatagca aaaatttcac ttaatttata tacagctttt
    11581 tcaaagtttc catacaaccc attcatagca gccaaaaaca aatttccaaa actctgacct
    11641 tttaaaagcc cttctgtaaa cctatattgc ataacttcat tcattgttgg ctctatattt
    11701 gcaagtgcta ataaacagtt tcttatgtct cctggtggga gcattcctaa gtcttctctc
    11761 aatacacctg aacctccacc atcatcagca acagttacaa ttgcagttat attttgcgta
    11821 gtgtgtttaa gacctcttaa aaataccgat tgaccagtac ctccacctat cacaaccaca
    11881 tttggttctc tattttcaac aatagacctt tgaaatagtt ttactttttc attttttgct
    11941 tttttatata taaataacga tacaattaat gcaatccaac ctaaaattcc tacaataata
    12001 agtaatttag ccatgtttgc ctccattatc gcaacataga gtctctatgt ttctttacaa
    12061 ctctatatcc cttattagat aaatcctccg ctataagatt tgttatagta actgacctat
    12121 gtcttccacc tgtgcatcca acaccaatta ctagatgttg ttttccttcc tctatatatt
    12181 gaggtactaa aaaatgaatc atatctaaaa gtttcacata aaattcttca ctgattttag
    12241 aattcataac ataatctcta acttctttat catcaccagt tttagctctt aactcttcaa
    12301 cataataggg atttggaaga aatcttacat caaatactaa atctgcatca gcaagtatac
    12361 catgtttaaa tccaaaagat actacagaaa tagttaggtt tggattatct tcaccagaag
    12421 aatatatttt ctttatttct tccttaaggt ctttaggttt catgttagtt gtatcaatta
    12481 tacatgtaga taactccttt aaaggttcca ttatctttct ttccattttt ataccttctg
    12541 gaatctgcat atcttttgcc aatggatgat ttcttcttgt cattttatat ctctttagca
    12601 atacatcatc attacaatcc aaatatacca tttcatattc ataattttct ttttctaaat
    12661 aatttaagct ttcatgaagc gcttcaaaaa actttctccc tcttatatct atccctagag
    12721 caactttatc aatacttgaa tttggttgat aacataattc tgcaaattta gttatcaaag
    12781 caggaggtag attatctaca caataaaatc ccatatcctc taaagctctc attgtctcac
    12841 tttttccaga tcctgaaaga cctgtaacta taacaaattt cattgctaac tcctcccttt
    12901 tatcttatgt ttattatatt ataatgtttt ctactaacga tatatccaga ttagagtcag
    12961 atatagtctt catagctagt tcaaaatcac caactctttc tggacaatgt gcatctgagc
    13021 ctattataaa tttattttct agccctttta ttttatttaa ttgatttaca ttcaaaaaag
    13081 aatggctact atttatctca agtctagtat ttgtcttttt tgctgtcttt gctacttctt
    13141 ctatatacac atcgccttta tctcctggat gagtaattat aaaaatatca ttattactta
    13201 tcgcatttat tacagctttt gtattatatt cttttgcttt ttcagtttta aaaatatagt
    13261 tattacaatg atttaataag cttcttaatg atgttggagt agaaccaaaa tgatatccag
    13321 ccataatata atcaaaatct ctaataaatt tatcatccat atctatattt cctttatcat
    13381 ctaatatgtt acactccata cctaaaagta tatttatatc agtgtactta tcatttaaat
    13441 aatctacttc ttctctcatt ttgagaatat cttttttctt tacaccatat gcaatatgtt
    13501 tataactatg gtcagatatt cctattgttt ttattccttt agaaatggct acctttacat
    13561 tatcctcaat agtccctttg ccatgactat ataatgtatg tgtatgataa tcagccagta
    13621 ttttcatttg ttaatcctct ccaagtattt tgacttcttc ttccaacata accccaaact
    13681 tggcatatac agcacttttt ataacatata ttaaatccaa aatatcttta gcacttgctt
    13741 ctccttgatt gactacaaat ccacaatgct tctcagatac ttgtgctcct cttaaagtaa
    13801 gacctctcaa tccagtttct tctattaatt tacctgcaaa atatcctgtt ggtctcttaa
    13861 atgtacttcc tgcactagca aaatttaatg gctgtttagt tattcttctc gtcgctaaat
    13921 catccattaa actttttatt tcatcataat ttccttcttg taattctaat tctgctgata
    13981 aagctatata tccgtttttc gatattatac tttttctata cccaaattcc atctgttcat
    14041 ttgataattc aaatatattg ccttccatat ccatcagtct tactgacttc actatatcct
    14101 tcatttcacc accatatgct ccagcattca tggctaatgc tcctcccaat gtgccaggta
    14161 ttcctgatgc aaactcaaac ccttttaatt cttgcttttg gagagctttc cctaaaactg
    14221 ataataaagc tcctgactga gcagtcatcc tagtatcatt tatctcataa gaattgaaat
    14281 tatcagctaa ttctattacc actcctctta ttccaccatc tttaattaaa atgtttgaac
    14341 catttccaat tattaaatac ggaatagact ctttttttac caacttaagt acatttttta
    14401 attgttcttc agttctaggt ctaactaata tatctgctgg tcctcctacc ctaaatgaaa
    14461 tatgtttttt cataggttca tcgactttta tatcctcttt acttaatata tttaataaat
    14521 ttatatatat atcttgatta ttcattgtat ttcctcccaa attatactga actttagctg
    14581 tcattattat ttaaattaca ttaatatata gtattaacta tattcaataa tatatgattt
    14641 tgcttatcat atggatttta tattttaagc ttcttaatta caaactatat tcaataaata
    14701 tataataaag taaaaaaaaa aaaataacaa catataaaag aatataaata atttaaaaaa
    14761 agcatcaata tcactgatat caatgcttta aaaggcaatt taattcgtat tatttatcta
    14821 actatttttg acatagcaaa gataataaat ccctccaact actatggaac ctccaacgat
    14881 atttccaagt gttacaaata ccaaattagt tataaattga accatagtta tatttgctcc
    14941 taatgccatt cccattggta taaaaaacat gtttgcaaca ctatgttgga atccacataa
    15001 tacaaatagc attattactg tccaacatga agccaatttt gacattatat cttgagatgc
    15061 tgtagccatc catacagcta aaacgactag aatattacaa agtattgctt ttaaaaacat
    15121 tgatgctata gttgaattaa ccttagcttc tgccacagct atagcttttg tagctgcatc
    15181 tcctgtcaat gtagaagaat aaaacacaag tgcaactagc aaaattgaac ctactaaatt
    15241 tgcaaaataa accagtcccc agtttcttaa catttttcct aatgttattt ttttgtccat
    15301 aagtgcaata gccattaaag tgtttccagt gaataattct gctcctgcca ctactacaag
    15361 cataagacct actggaaaga ccatagcact taaaaagcta gctacccctg ggtctatctt
    15421 gccaaaagtt tgactaacta tcatactccc caatgcccca aaacctataa atgctcctcc
    15481 aaataaacct aatagaattg cattttgtgt cgaaatattt gcttttttaa tgcctgcact
    15541 tatagttgct tgtgcagttt ccccaggtgt caagaatcct ttactcataa atccttcccc
    15601 cttaaaaatt atactttccc ttgtcttttt atggcaataa ttatataata acaatatgat
    15661 atataataaa ttttattaac ataaaaaata tactatatac ttatatatac ttgtctcata
    15721 taattatact atttattata taacaacttt gttaatttcg aaataattta tattgaattt
    15781 gaaaaattta ccttttgatt atttatttta ctttttaatt attgaggtat tatatataat
    15841 agatatatgt ttgtgttatt atatataatt acttatttta ataaatattt gaaggaggga
    15901 attttatgtt tgatatatca tttttcgaaa tgtcaatata tgaaatagca gttactacaa
    15961 tatatataat taatttcatg gttatactaa accttatctt tagagaaaaa agaaacataa
    16021 atacaacttt aacatggctt cttatattag tattgattcc tgctcttgga ttcatacttt
    16081 atatagcttt tggcagaaat atttcaaaaa acaatatgtt tagattgaaa gaaaaggatg
    16141 ataagataat caaaagtaat atactagata ctcaggttaa actccaatct acatctgaaa
    16201 ttgattcaga tatacatcaa cataaggata tgatttatgc attggctaat tcaaataatg
    16261 ctcattatac caataataac gatgtgtgga tttatgctga atctagtcaa ttttttaaca
    16321 gtcttcttga agaacttaaa aaagctaaaa aatatataaa catacaattt tacattttca
    16381 aagatgacaa aatcggaact gaaataatag acattcttat agacaaagct aaagaaggtg
    16441 ttgaagtaag acttttattt gatgcagttg gtggtagaac actaaaaaat agtacacttt
    16501 ccagacttaa agaaagtggt gttaaagttg gaagcttctt cccatcattc ttgaaaattg
    16561 taaactttaa cttaaactat agaaatcacc gaaaaattgt tgtcattgat ggtaaggtag
    16621 gatttgtagg tggatataat gttggtgatg aatatttagg tagaaatcca aaatttggtc
    16681 tatggagaga tacacatact aagcttactg gtgattgcgt aattgaccta aatatgagat
    16741 tcatccttga ttggagatat acaactaaag aagacttaga tttagaaaaa tactttatag
    16801 aagaagatac aaattctaat catccttctg aaaatattgg gattcagata gtatcaagtg
    16861 gtccagatat atcagaactt gatgagatta aatatggtta ccttaaaatg attcagaaag
    16921 ctagaaagta tatatacata cagagtcctt atttaatact tgactcaact tttatagata
    16981 ctttaaaaat agcctgttta tctggtgttg atgtgagagt gatgattcct tctaaacctg
    17041 accatccctt tgtatactgg gcatcatatt catatgctgg agaactttta aagtttggag
    17101 ctaaaatcta tacttatggt caaaatgcat ttttacatgc taagacaata gttatagatg
    17161 actctatatg ctctatagga acagctaata tggatatcag aagttttgag cttaatttcg
    17221 aagttaatgc atttatgtac tcttcaaaaa aagcattgga acaaagaatt atatttgaaa
    17281 atgatatttt aaattctaag gaaataacat tagatatata taattctagg tctacttata
    17341 taaaaatcaa ggaatcaatt tcaagactat tatcagcagt tttataaatc ttttatttta
    17401 taaaaatttt acattttggt ttatttttta aagtttttta tatgtattat ttttttttta
    17461 ttgaatttag ctcatttttt ttattttttt taactattct gaattatttt atattataat
    17521 agactagtat agtttttatt tttaataggt aacttttttg cattgttttt ataaataaag
    17581 aaattgttgt atattattct ttctttattg ttttggtttt gttcacccac ataatgttgg
    17641 ggtcaactca tggttaatta ttttatgaaa aataataact ttaaaaagaa aagggggatt
    17701 tgttatgtgc gattttattt cacacaacaa gcaattattt gacgaactag atatatttat
    17761 tgactctctt gcaacaaagg aaggtgcgtt aatacaagtt ctacatgaag cccaaggtat
    17821 atttggatat cttccaaaag aagttcaact tcatgttgct agaaaacttg gagtagctcc
    17881 tgcaaaggta tatggggttg ttacattcta ttcttatttt actacagaac ctgtaggtaa
    17941 gtataaaatc agtgtctgtc taggaactgt atgttttgta aaaggtgctg acaaaatctt
    18001 aagtgctttt gaaaaacagc ttggcataaa agttggagaa actactagtg attttaaatt
    18061 ttctttagaa ggtttaagat gtttgggggc atgtggttta gctccagttg ttactgtaaa
    18121 tggtaaagtt tatggtaaag tgaaacctga ccaagtaagc gaaatattag atacttatag
    18181 agaattagaa ttgaattgtt aagaggggtg aataaataat gcgtaaagta aattcatttg
    18241 atgaattaaa agttttagct gatgagctga aacctaatct tagcttaaga aaaaattatt
    18301 ctaaggaaaa tgtattaaga agagaattac ttgtttgttg tgatactgga tgtacatctt
    18361 caaacagtct agaaatagtt agtgaattag aaaatgaaat aaagaaatca ggaatccaag
    18421 ataaagttag tgttcgtttg acaggttgtt ttggtttctg tgctcaaggt cctattgtaa
    18481 aagtttatcc tgataacgtt ttctacgtaa aagttgagcc atctgatgct gaaaagatag
    18541 ttcaaagcca cttaattaga aatacagttg tcgaggaatt attatatgag gaagaatctt
    18601 taagtaaaaa agttgaagaa caagaagaaa tgtctttcta caaaaaacag ttacgtatag
    18661 ctttaaaaaa ttgtggtctt atagacccag atagtataga agaatatatt gccaatgatg
    18721 gttatttagc tctaggcaaa tgtttaactt ctcttactcc tcaagaagtt attgcagagg
    18781 taaaaacttc tggccttcgt ggtagaggtg gtgcaggttt ccctactggc tctaaatggg
    18841 aagctgcttc aaaaaatcca gctggtccaa cagataaaaa gtttgttgta tgtaatgctg
    18901 atgaaggtga cccaggtgca tttatggata gatctgtact tgaaggtgac cctcatagtg
    18961 tactagaagc tatggcaata tgtggatacg ctataggttc tgatacagga tacatataca
    19021 taagagcaga atatccaaaa tctatagaaa gattaaaagt agccatagct caagctgaaa
    19081 aatacggttt acttggcgaa aatatcttag gcactggatt taactttaaa ttagaattaa
    19141 aatatggtgc aggtgctttc gtttgtggtg aaggtacagc gctaatgcat tcaattgaag
    19201 gtagacgtgg tgaacctaga atgaaaactt atagttcttc taagagtggt ctatggaaat
    19261 ctcctacttg cttaaataac gttgagactt ttgctaacat acctgcaatt atacttaagg
    19321 gtggagattg gtttgccaac ttaggtactg aagattctag tggtactaaa gtctttgctc
    19381 ttggtggaaa ggtagaaaat gtaggacttg ttgaagttcc aatgggtact actttaagag
    19441 atattgtatt tgaaattggt gggggaatcc ctgaaggtaa gaaatttaag gctgttcaaa
    19501 caggtggacc atctggtgga tgtataccaa ctgaacattt agacactcct atagactttg
    19561 gttcattaag ttctatcggt tcaatgatgg gctctggtgg tatgcttgtt cttgatgaat
    19621 ctgactgtat ggtagatata gccaagttct tccttgagtt tactgttgaa gaatcttgtg
    19681 gtaaatgtac accttgtcgt ataggtacta caagattatt agaaatatta actaaaatta
    19741 cagaaggtaa tggtactcta caagatttag atgacctaga aaaccttgct gaaactatac
    19801 aaactgcttc attatgtggt cttggtaaag ctgctccaaa ccctgtttta agtactcttc
    19861 aatatttcaa agatgagtat atagctcatg ttgtagataa gaaatgtcct gctggtaaat
    19921 gtcagaactt actttcttac tttataacag atgactgtaa gggttgtaca aaatgttcta
    19981 gagtgtgtcc tgctggttgt ataacaggtt ctgttaagga acaacataca atagatactt
    20041 ctaagtgtct aaaatgtggt gcttgtatag ataattgtac atttaacgct ataatcaaga
    20101 aataacttat ttggaggagg aataacaatg agtttagtta atttaactat taatggcaaa
    20161 cacgtttcag cacctagtgg aacttctatc ttagatgctg cgaaattaat aaatataaaa
    20221 atacacaacc tttgtcattt acatatgaat gaaatagata agcttgacac ttgtgcttct
    20281 tgtcgtgttt gtatggttga gacagagaga ggattagttc cagcttgtgg aacagttata
    20341 aaggaaggta tgaaagttca gactaatagt gctaaagcat taaatgctcg tagaactatt
    20401 gttgaattat tgttatcaga ccatccacaa gattgttttg tctgtgaaaa aaatggagat
    20461 tgtgaattac agactatagc tgctgattta ggagtaagaa aaataagata tcaaggttct
    20521 aaatcttttg caggtaaaga tacttctact aaatctttag ttaaagacca ttctaagtgt
    20581 atattatgta gaagatgtga gactgtatgt aatgacatac aaacagtagg agcattatct
    20641 ggagttaatc gtggatttaa tactttagtt agtacattct ttaactctga tatggttgaa
    20701 acagagtgta cattctgtgg tcaatgtata tctgtctgtc caactggagc attaacagaa
    20761 gtagataatg tacctaaact ttgggatgtt ttaaataaaa aagaaaagac tatagtagtg
    20821 caagttgctc ctgctgtaag agttgctatt ggtgaagagt ttggattaga accagggtca
    20881 atctctacag ggaaaatggt agctgcttta aaagcacttg gatttgaaca tgtatttgat
    20941 acaaactttg gtgcagattt tactataatg gaagaagcta ctgaatttat agaaagaatc
    21001 caaaaaggtg aaaatcttcc tatattaaca agttgttgtc ctgcatgggt aaacttctta
    21061 gagcacaatt atccagacaa gttaaactta gcatctagct gtaagtctcc tcaaggtatg
    21121 tttggttcta tagctaaaaa ctactatgca cctaaaatat taggaatcaa tcctgaagaa
    21181 ctttatgttg tatctgtaat gccttgtgta gctaaaaaat atgaagcttc aagagaagaa
    21241 ttaagtgaat ctggaatact agatgttgac ctttctataa ctactagaga gttagctaag
    21301 atgataaaag aagctgcaat cgatttacct aatcttcaag accaagattt tgataatcct
    21361 ctaggaaaat ctacaggtgc tgcatctata tttggagcaa gtggtggagt tttagaagct
    21421 gccctacgta cttcatatga gaagataact aataagactt tagataatgt aaacttcact
    21481 aatgttagag gtcttaaagg aattagggaa gcaagtatag atgttgatgg aactacagtt
    21541 aatgtatgta ttgtaaatac acttaaaaac gctagaaaga ttatggataa ggtcagaagt
    21601 ggagaatgta aataccatat catagaagtt atggcatgtc ctggtggatg tgttggaggt
    21661 gctggtcaac cttatcacca tggtaatact gaaatagttg atagacgtgc aaatgcgtta
    21721 tatgaaatag atagaaataa ggctattcgt aaatctcatg agaatcctga tttacaagct
    21781 atttataaag acttctttgg agaaccaaat agtgatgtag ctcataaata ccttcatact
    21841 cattactttg ataagagttg tgtctatgga gagtgtccac aagaatgtgc ttgtgaagaa
    21901 gctaagtagt cataacaaag tataaaattt attcttaaaa aaggattgtc ttaaaatact
    21961 tttacgtaat ttaagacaat ccttattaat ttcacaaatt aaattatatt tctaaataga
    22021 cttatttatt aattaaccta tctattaatt aaagaatacc tgccattctc ataagttgtt
    22081 ttgcatttgt agttttacat cttccatctt ttatcttata gtcaaaatga attttatcgt
    22141 ctacatagta ctctgagaaa tgatagttta caacttcaac atctccgcta cctgaaaggt
    22201 cacatagctc aaagtcatgt gttgtcacca tacttataac ccagggtttt gataatttct
    22261 ttactgcctc acttgctcca ataattctat cagcagagtt agttccctta aaaatttcat
    22321 ctactagaac caacattggc agttctttta aactatattg aatcattgat tttattctaa
    22381 gaatctcagc atagaaagtt gatattcctt gacttacatc atcttgtatt ctcatagaag
    22441 taaatatagc catacaggtc gcatcaaaac tcttagcgca tactggagca cctgcatatg
    22501 ccagcactaa gtttacaccg atacttctta aaaatgttgt ctttccagac atatttgaac
    22561 ctgtgataat acaagtctga gaatttaatt gtatcgaatt tgctatgaca cttttttctg
    22621 ctattaatgg gtggtatacc tcttcaactt tcaatcttgg agtatcttca tattttatta
    22681 ctggaaaaca tgtattttcc tttacatgag aaacaactgt taaacttatt agagcttcaa
    22741 attctccaat agattcaaac caatctctaa tttgatttcc atatatacct ttccatcgct
    22801 ccaaagcttc tgcacaatga tagttccaca tcaaaacacc acaggcaatt atatatagta
    22861 tctgattata ccttaggttt acagcatttc ctattgaatt taattgttta acacctcttg
    22921 aaactccact tcccttagaa agtttatctt gtaattcttt caaatatgca ctctcaaacg
    22981 tctctttttc taaaacctca aacatttttt catatacttg tatacttcta ctaaatgaaa
    23041 ataatggagc aagagtttgc ataagtcttg gatatccaaa accactaaac cctaactgga
    23101 ttataaaaag taaaaaaaca ggtaaaacag gtaaaaatcc taacatacaa aatataaaag
    23161 ataagattgt tgcagttggt aaaccccaag taaaaatatg catccatttt ggtatataca
    23221 cattcttatt ttctccatat tctataaacg attctatact actatctgaa ttgttttttt
    23281 gctctttacc aattatatta ctgagtgttt gaatatgaat agaaaaatca tcttttgata
    23341 aaagttcttt tatagctctc tgtctttcta aaattatatt ctcatctgga ttttcattcc
    23401 acaaatattt ggctaaaaaa tttttcccat aagatgtatt agctacacag atatattgat
    23461 acaatgatgc tcttccaaat aagtctaaat cttttgcttg cgaattttca tcttttaagt
    23521 attctttacc atctatttta aattccttcc aaccatctcc aaatctctta atatacttat
    23581 ttaatacttc gctcttactt ttaaaatatg tttcttcttc ttttacttta ctatgaataa
    23641 ctaagagtgc tataaatatt attattgata aaactccaac aaaaatacct actatatttt
    23701 tattataaaa tccaatagca agccctgcta tcactatcaa aaaagatatt aatcttgctg
    23761 tacttatgtt atttgacttt ttacttaaga gcaattcttt ttcagtacta ctttctaaaa
    23821 gtttactaaa atattctatt cccataaaaa attccaactt tcttgttata taatgaaact
    23881 caaatataaa attaatctag tattattata atctaacact gtactttaaa ttatccttat
    23941 ataatatatc ttattaataa acattatata tacaacttga ttttaattta taaggtgtag
    24001 gacataatcc taatcaatat ttaattaaat gatgtgtagt ccactattat tcagtactac
    24061 ttagtatcga ttaattttga taatttttta gtaaattctt gagctgcatc gtatcccatt
    24121 cctctttgtc taaaattcat tgctgctact tctaatatca tagcagtatt tcttccaggt
    24181 ttaacaggta caactaattt ctctacatta acaccaagta tttcttcata ttctttatcc
    24241 agtcctagtc tatcataata cttagtttca tcccaagctt ctaaatgaac tactaaatct
    24301 atcattttag aatttttgat tgcccctact ccatataaac ttctaacatc tattattcct
    24361 attcctctta tctcaagaaa atgtcttatt agttcaggtg actgacccac aagcatactt
    24421 tcatctaatt ttcttatttc tacagcatca tctgcaacta atctattacc cctttgaatc
    24481 agttctaatg ctgtttccga ctttcctata ctactttcac cttttatcag tacacctata
    24541 ccataaatat ctactagcac accgtgaatt gttgtatgtg gtgctaactt attatccaaa
    24601 tagtttgaca gtctatttat aagtctagtg gtatttctat ttgtgctcaa aagtattctt
    24661 ttatattttt tagccttttc aattacatct ggcttgattt ccaagtctct agaaattatt
    24721 aacgctggta tttcatatga gaaaaatcta tctagtactt cttcccgaat atgactatcc
    24781 attaatccaa aaaaattata ttctgtcttt ccaactattt gtattctttc atatgcaaaa
    24841 taatcaaaat atcctgcaaa ctgtaatcct ggtctattta tatcttgaga gtagacataa
    24901 taatctacat catcaggcat gtatactact tttaacttca actcttttat tatctctctt
    24961 attgatactt tattgctagt ttccattaat tttcttcctt tctaaaaaaa ttataaacat
    25021 tatctgcaat gcttttattc attccatcta cttctaaaag ttcttccata gtagcttttt
    25081 ttatagcatc tacatcttta aagtgattta ataatgattt ctttcttttt tcacctattc
    25141 cttgtatatc atctaagata gattttgtca aagctttatt tcttagactt ctatgatatg
    25201 ttattgcata attatgaact tcttcttgta tactagcaat aaatctatat aaattagttg
    25261 ttttatctag ttctatttct ttttctttgc atatcaatcc tttagttcta tgcttatcat
    25321 ctttgtacat tccccaaaga ggtatatcta catcattgag ttctagtact ttttttactg
    25381 cactaacttg tccttttcca ccatccaaca atatcaagtc aggtaaattt ccatgtttta
    25441 atcttctatc tacaatttca gccatagaat cataatcatt aggtccaata actgtcttta
    25501 ttttatatct cctatattcc ttcttatctt ttttagcatt cgtatacact accatagaac
    25561 caatcgaatc tacaccttgt atatttgata tatcataagc ctctattctt attggcaact
    25621 tttctagatt taatatttgc tttaattctt ccaatgctcc aatacttttt tcatattttc
    25681 ttttattcat atcagaaaat ttttcaagat attctacagc atttttccta accatttcaa
    25741 ctaagctttt cttctctccc ttttgaggaa ctcttattgt tactttttgc ccctttttag
    25801 atgacagcca ttcttctaat atagaactat cttctatctc atcttctata attaattctt
    25861 taggtatata ctcttgttca ttataaaatt gttttacaaa tgaacttaat atagaagctc
    25921 ttggactatc cattacccct tctaatataa aatgttccct acctacaatc ttaccatttc
    25981 ttataaaaaa tacctggaca caagcttcat tatgagctct tgccattgca accacatctt
    26041 ggtttaagtc acttacagta gcatctattt tttgtttctg tatcatctct tcaaggctct
    26101 ttatcttatc cctatataca gcagcctctt caaatctaaa gttcatagaa ctctcattca
    26161 ttttttcctt taaaagttcc atcaattttt cttctttacc agataaacac attataatct
    26221 cttctatcat ttttccatac tcttctttag aaacatttcc tgtacaaggt cctaaacatt
    26281 tatttatgtg tagatttaaa caaggtcttg tcttattctt tattgcttta tctatatcta
    26341 ttttacagct tcttattgga tacgtactac ttataagctc caaggtatca ttcacagcag
    26401 ttatattggt atagggccca aaatactttg ccttatcttt aagaactctt ctaactttta
    26461 agattcttgg ataatcttca ttcgtagtta cttttatata tggataagtt ttatcatctc
    26521 taagcactac attatacttt ggtctgtatc tttttattaa attacattca agtattaatg
    26581 cctctaactc tgaatccgtt ataatatact caaacttata tatattctta accatagatt
    26641 ttactttaga tgtatggttt tttgaagatt gaaaatactg ccttacccta ttttttagag
    26701 atatggcttt tcccacatat attatatggt cgtatttgtc tttcattaaa tatactccgg
    26761 gctcagaagg taattttttt aaatgctctt gtatatcaaa catctcgccc tccaaaacat
    26821 taaattttat actaaaatta taccctaaaa tatgaatttt aaaaagttat acaatttcca
    26881 gtgctttaaa caagttaaag cccatattcc cttctataat tgatttgaaa acaatgttaa
    26941 ccatgaagag taatatggac tttactttgt attactattt acaacttata tttgactaat
    27001 ttacttataa caaaacagtt tatcgtatat ctgctctaaa atttttcaca atttatataa
    27061 cttaagaaaa atatttcttt aagaattgac ctgtataaga accatcaact ttagatactt
    27121 cttttggtgt tccagttgca actatagttc cacccttatc tccgccttct ggtcctaagt
    27181 ctattacata atcacaagtc tttataacat ctaaattatg ttctatgact ataattgtat
    27241 ttcctgtatc tgctagtctt tgtaatactt ggattagctt gtctacatct gccatatgaa
    27301 gtccagtagt aggttcatct aatatataca aagtctttcc tgttggtctt ttactaagtt
    27361 cagcagctaa ttttatacgt tgtgcttctc ctcctgataa ttgagttgaa ggctgtccta
    27421 atttaatata tgaaagtcct acatccatta aagtttctaa ttttcttttt atatttggta
    27481 tattttcgaa aaactcaaca gcttcttcca cattcatatc taatatatca gatatagttt
    27541 tatctttgta ttttacttgc aatgtttctc tattgtatct ttcaccttta caaatttcac
    27601 aaggaacata tacatctggt aagaaatgca tttctatttt tattattcca tcacccttac
    27661 aagcttcaca tctaccacct tttacattaa aactaaatct acctttttta taacctcttg
    27721 ctttagcttc attagtagat gcaaaaatat ctcttataaa atcaaataca cctgtataag
    27781 tagcaggatt tgaacgaggt gttcttccaa taggactttg gtctatattt ataactttat
    27841 ctatactttc aattcctttt atctccttat gcttaccagc tctttgctta agtctattca
    27901 ctttacttgc aacacctttg taaagtatat cgtttattaa tgtacttttt ccagaacctg
    27961 aaacacctgt tatgcatgta aacttaccta atgggaactt tacatcaata tttttcagat
    28021 tattttctga tgctttaact atttctataa aacttccatt tccttctcta gtagtctcag
    28081 gaagcaatat ttgtttttta ccacttaaat attgacccgt tattgagttc tcattttcaa
    28141 ttatttcatc taaagtaccc tgtgcaacta tttcaccacc atgtatacct gcacctggac
    28201 caatgtctat aacataatca gcttctctca ttgtgtcttc atcatgctct acaacgatta
    28261 aggtatttcc taaatctgtt agatgtctaa gagtagttat aagcctatca ttatctcttt
    28321 ggtgaagccc tatacttggc tcatcaagta catataaaac tccaaccaat gcagaaccta
    28381 tttgagtagc taatcttata cgttgcgctt ctcctcctga taaagttcca gcttttcttg
    28441 ataaatttaa ataatcaaga cctacatctc ttaagaacat agctcttcct tttatctctt
    28501 ttataatctc atgagctata aatctctgtt tttctgtaag atttatattt tccataaagt
    28561 caatcaattc atttacagat aagtttgtaa cttccattat attttttcca tcaactaaaa
    28621 cagataaaac ttccttttta agtctcatcc ctttacactt tggacatggt ctctctgcca
    28681 tgtattcttc aatcttatct ctcatgtaat ctgaattagt ttctctatat cttctctcta
    28741 agtttactat tacaccttca aagtatgatt tataatttct agttcctcca aattttgact
    28801 cataagtaaa ctctacaatt atattatctt taccataaag taattcctcc acaaaatcat
    28861 ctggtaaatc tttaaacggt gttgtcaaag atacattaaa atgctctgct aaacttttta
    28921 tcattttact gtaataagtg tcatcattaa cacctgttga accccatgct gccactgcac
    28981 cttgttttat tgataaatct ttgtttggta ctactaattc tgggtcaact tctttacttt
    29041 ccccaagacc attacaaaca tcacaagcac caaagggagc attaaatgaa aacattcttg
    29101 gagataattc ttctatgcca attccatgtt ctgggcatgc aaatttagtt gaaaaaagaa
    29161 tttcttctcc atctattatt tgggctatta caagaccatc agatagctta actgcagttt
    29221 caattgaatc tgctagtctt gattctattc catctttaat tactattctg tccactacaa
    29281 cttctatatt atgtttttga tttttattta agattatatc atcactaact tcatagtttt
    29341 caccattaac tctaactctt acaaatcctt cttttttgat attatcaaag acttttttat
    29401 gtgtaccttt ttgtcctcta acaattggtg aaagaatttg taatttcgtt ctatctggaa
    29461 aatctagcat tttatcaact atttcttgaa tagtcatctg acttattttt tcaccacatg
    29521 tagggcaata cacatctcct actcttgcaa ataatagtct caaataatca tatatttctg
    29581 ttactgttcc aaccgtagaa cgtgggtttt ttgaggtagt cttctggtca attgagatag
    29641 ctggtgataa accctctata tattctacat ttggcttttc catctgacct aaaaattgtc
    29701 ttgcataagc agatagactt tctacatatc ttctctgtcc ttctgcatat attgtatcaa
    29761 atgccaaaga agacttccca gaccctgaca aacctgtaaa aacaataaat ttatctcttg
    29821 gtaattctaa atctatattt tttaaattat gttcttttgc tcctcttatt ataattttat
    29881 cttccataat gttgttttta cctttctatt tttccaattt ttcttctaat tgtttcactt
    29941 tatctctaag ttctgctgct ctttcaaatt gtaagttttg agcagcttcc atcatctctg
    30001 attttaattt atctatatta gctcttattt cgtctttatc atctgtatca gatattccat
    30061 atacaacttc ttcctctgca accttagtag cttctatact atctcttata tttttctgta
    30121 tagttttagg aatgatattg tgctcttcat tatataaatt ttgtatatct cttcttctct
    30181 ttgtttcatc aatagcattt tgcattgagt cagttatcct gtctgcatac ataattactc
    30241 ttccattttc atttctagct gcacgtccaa tagtctgtat taaagctgtt tcggaacgta
    30301 agaaaccttc tttgtctgca tctaaaattg ctataagtga aacttctggt atatccaatc
    30361 cttctctaag taagtttatt cctacaagga catcaaactt ccctaatctt aaatctctta
    30421 ttatttctgt tctttctaat gtaactatat ctgagtgtaa atatttaact tttatcccta
    30481 tttctttaag atagttagtc aagtcctcac tcattttttt agttaaagtg gttataagca
    30541 ctctttcatt tttttctata gttttagtta tttctcctac caaatcatct atttgattat
    30601 ttataggtct tacttctaca attgggtcta aaaggccagt tggtcttatt atctgttctg
    30661 ctattgtctc tgagtgttga atttcataag gccctggtgt agcacttaca aacaacattt
    30721 gatttatatt tccttcaaat tcttgaaaat ttaatggtct attgtcaagt gcagaaggta
    30781 atctaaaacc attctctata agtgatgttt ttctagacct gtctcctgca tacatacctc
    30841 ttacttgtgg tatagtgaca tgtgcctcat ctacaattat caaataatca tctgggaaga
    30901 aatccattaa agtatatggt ctttctcctt ctgaccttcc tgtaatatgt ctagaatagt
    30961 tctctatccc ctgacaaaat cctatttcct ttaacatttc tatatcatac ttagttcttt
    31021 gttcaattct ttgtgcttct aatagcctat cattttcctt gaaaaattta atttgttctt
    31081 gaagctcgtt ttctatttct acaattgcct tttcaattct ttctggcgtt gttacatagt
    31141 gagatgctgg gaatataaca acatgatttc tagtaccaac aatcttccct gttacataat
    31201 caatttctgt tattctatct acctcatcac caaaaaattc tattcttatt gctttttcat
    31261 cattactagc tgggaatatt tctagtatat ctcctctaac tctaaaggta cctcgtgtaa
    31321 agtttatgtc atttctttcg tattgtatct ctattaacct ttttattaca tcatctctgt
    31381 ctctttgcat acctggtctt atagataaca taagttcttt atagtctttt gggtcaccaa
    31441 gtccatatat acaagataca gatgatatta ttatagtatc tcttctctct aaaatagatg
    31501 ctgtagcaga atgtcgaagt ttatctattt catcatttat gcttgcatct ttttctatat
    31561 aagtgtcact gtgagctaca tatgcttctg gttgataata atcatagtaa cttacaaagt
    31621 attcaactgc attgtctggg aaaaattctt taaactcact gtaaagttgt gctgctagag
    31681 ttttattatg agccattatt agggtaggtt tcttaacttg ttgaatgata tttgccattg
    31741 tgaatgtttt tcctgaaccc gttacaccta ataatgtcga aaatttctca tttctattta
    31801 tagaatccac tattgattta atagcttctg gttggtcacc tgtaggtttg aagtctgatt
    31861 ttattttaaa atccatagta tcactccttt tttcgaacat tagttcctga catgtattat
    31921 tatatcatac ctttataaaa ttgtttaagt tattttaaat attttaccca tttaaatttt
    31981 acttaaatct aaaacataaa aaaagacttc tatctttgca atagaagtct ataattcatg
    32041 gaaaataaat actttattca acttacataa taaaatcaaa tgcttctttt tcaactccat
    32101 ctaattttaa attaaacatt tttaatatag ttgctgcatg tgctctcagg tctccttctt
    32161 ctataaccac accaccttta atatttggtc caaaagctat aaatggaggt ctattacctt
    32221 tagtaggtaa atgaccatgt gtcgcaacag caaacttgta atcttttata tctgaatctt
    32281 ttataatact tccttcgaaa tcatttccaa atgaaattcc ttcaagacct tcaattacca
    32341 tttcaaaatc accttcaaga ccaaggttag atgcttcctc tttggtaaaa atattctcta
    32401 tgaataattc ttctttaaat tcttcaagca gttctcttaa ctctgttaac ctatctaagt
    32461 tatttactat tatttgagct gatattccag aagaatttac ataggcatca aaatccttaa
    32521 cttctccatt ttcaactttt ataaatccat ttgatttaag caagacattt ggatttataa
    32581 ctttatcaac tctaagatga ccatggtccc caagtattat aaaatttgta tctttgtatg
    32641 tacctgcatc ctttgtagcc tgaataatat ctcctagcca tttatcattc atttttaatg
    32701 ctttatctac ttcgtcatta aataagccat aattgtgtcg tgtatggtcc aatgtagcta
    32761 aatgtattag cattaaatct ggtttatatt cctttattat atctactgaa cagtttactc
    32821 caaataaatc catgttgggt tctaatttcc aatcgatata atgacaatgt ctattgtaaa
    32881 taccgtccat tataacctta ctggaacttc gttcaaaagt ttctcttggg tcatcttctc
    32941 tactaggagc ccatatttct gcaatattat aatctatatt tggatttgct cccattacag
    33001 gccataatac actagaggta gttagattat tttcttttgc tacatctata atagtttttg
    33061 cttttatgtc ctttgagtac cagtaccagt ctttattttc tttatttggg tcaaattttt
    33121 cattatgata tataccatgt tttttaggat atactcctgt aaccatacta gtatgacacg
    33181 gatatgtcag agtgggataa acacaattta tattttttac tatggagcaa ttttctagta
    33241 tagatttaaa gtttggtaga ttttttacaa attccaagtc tttttcaaat aaagaatcta
    33301 ctgataatac tataaccttt gtcatttaca ttacctcttc atttatatat tattgaatac
    33361 ttttaatcaa cttacaagtc tatataatta tttatttgtt ttatctatta ctgcttgcat
    33421 tgcagaagtt cctttgctta ctacatcttt tggatttgca tttaaatcag taagcccctt
    33481 tttaatctca tccattagct tatcagttgc ttccttgtat ccatttaaca ttggaagtgc
    33541 aacagcatat tgtaattggt cagttgcaac cttatattga ggtttttctt tatataatgt
    33601 ttgtaacttt tctgagtttg ttgcatcttc agttgttggt aagtatcctg ttgatgaact
    33661 aaactgaacg attttatctg tttgtgtcat ccattctata aattctgcac ttgcttcttt
    33721 ttctttatct gttccacctt caagcataac tagattagct ccacctgtag gagttgcgta
    33781 tttttgattt tttggtaaga atgctgttga tatttcaaac ttaccttctg tttgttgcat
    33841 aagtcctgct aaatctgctg ttgatgtaaa tatcatacct actttaccat ttacaaaatc
    33901 ttgttttgct acgtcccagg cattataatc ttctccagga ggcattttca ttattccagc
    33961 tttcatcata tcttgccaga acttaactgg tgcttgtcct gcctcattat taaatgctac
    34021 ttttttacca ttagttattt ctcctccact ttgcattacc atagcttcat agaaccaaat
    34081 atctattggt gtttcaaaac cataagtatc ttctgattta tttgtcattt tactagcata
    34141 atccttaagc tcttcccatg attttggacc tgaagggtca agacctgctt tagttgccat
    34201 atctttattt atgtataata ttggtgtact tctattaaat ggcataccaa caaacttatc
    34261 ctcataatat gaatttgtta aaagaccaga aaagaatctt tcttgatatg ttttatcaaa
    34321 atatttactc atatctacta aagcacctgc tgatgcgaat gtacctgttt gagttatttc
    34381 taataatgtt acatctggtt ggtctttaga tgttaaggct gcctgtagtt ttgttgcatt
    34441 ttcatagtaa tctttctgtt ttaacatatt tacttgtaca tccttatgtt cactattaaa
    34501 ttggtcaacc attttttgag cagtttctcc attagttcca cctaaaggag cccagaaatc
    34561 tatcttcgta atattgctat cagtcttttc tcctttagat gcatttgcat cattagaatt
    34621 tgaacaccca actaaagaac ataataataa tgttattgct aatcctgttg ctaattttct
    34681 tttaagcttc attttcatcc tccaaattta gtctttaatt ttttatttta ttcctgaata
    34741 cataaaagct tcttttactt ttttattcgc aaatatataa acaagaatta ttggtaaaat
    34801 tagaattata tttcctgcca ttattacatt ccatgcagta attccttctg aagatttaag
    34861 gagcgcaact cctattggta aagttcttat tgcatctgta tttgtcatta ctaagggcca
    34921 gaaataatta ttccaatggt atataaaatt aaataatata aatgttatta ctgctggttt
    34981 tgccatagga accattattc taaacattat ttttaagtca gaagcattat ctagtttagc
    35041 tgcttcaata atttcatctg aaatctgcat aaaattctgt ctaagcagaa atatcccaaa
    35101 tgaagatgtc ataaatggaa ttataagtgg aacataagta tttataaatc caaacttact
    35161 catcatcata tagactggta gaaaagttac ttgtggtgga atcataagtc ctacaagcaa
    35221 aagcccaaat agcatttttt cacctttaaa tttaatctta gaaaatgcat atgctgctgg
    35281 aaccataact aaaaattgta caattaaaac acttcctgtt acaaatacac tgtttagcaa
    35341 atatctaaaa aatggacctg aatgccatgc tgtactataa ttttctaaca ctatatcatt
    35401 tggtataata gtgggcggta attgcatcat ttcttgtgga tttttaaagg atgtagatag
    35461 catccatata aaagggaata taaatattgc agataaaagt aatagaatta atatttctat
    35521 tgattttgat gctatttttt ttatatcaac tttgtctttt ttgataggtt gtataatatc
    35581 cattgtctcc tccttttgga taaaccttat aatatctact ttttctttat tgataatgaa
    35641 ctttctttga taagagtcta aagttagcat atgtagcaat cataactata gctaacaaaa
    35701 acatactcgc tgcactcgct tgccctatgt catagtatat aaatccagac tcatatatat
    35761 aataagataa catgttagtt gaacccactg gcccaccttg tgtcattata cttatctcat
    35821 caaatacttg aaaagatgca gttgttgttg ttatcataag aaaaaatatt gttggtgata
    35881 atagtggcaa tgtcacttta aagaaattcg ttattttgtt tgcattatct aatttagatg
    35941 cttcatatat atagtttggt atggatttaa gacctgataa cactattaag atattatatc
    36001 caagagtctt ccatattcct attagaatta gtgacattaa agctgaactt tcacttgaaa
    36061 gccactttga tgttggtaaa tgtaatgtcg atagtatcca gtttaaaaag ccatattgtg
    36121 gctccataat ccaaagccac aatacagcta cagatactag tgaaattaca tgtggtgtaa
    36181 agattatact ttgcgttaaa ttgtgtatta tagaattttt atttagccaa acagcaagta
    36241 ctatggctag tgatatagat atagtcacca taaaaaaagt ataaattgca gtgtttgtta
    36301 tagtttgtat aaactctgga ttctttaaaa gttctgtata attgtttaag cctacatttt
    36361 caaaggttga actaagaaga ctaccagatt tgaagcttag agatatcgtc ttaattattg
    36421 gatagactat aaacaataaa gttcctataa tagcaggtgt tatatataaa tatgctttat
    36481 taaattgctt tttcataaat atctcctttg attttagaat acatactttt acatactttt
    36541 acatcttcta ttctttctcc atttttatca aaataatata aatctttttc taatacactt
    36601 attcttaaag ttcttccaat atcaaatata tcattttccg ttttgactct tatctctcta
    36661 ttaagaacag ataaacaata tatagtttca tttcccaaca cttctttagt tacaactttt
    36721 ccaaatagac taaatacatc atcatttttc ccatctatgt ttatactctc tagtgttgct
    36781 ttttctggtc tgaatccaaa tttaatatca ttttttatat ctagtatgtt catacaagga
    36841 ctccctataa attgagctac aaataaattt ttaggatttt gatatatctt ctttggagaa
    36901 cctatttgca ttatctttcc tttgttcatt ataactatct tatctgccat tgacattgcc
    36961 tcaacctggt catgagttac ataaacaaat gtagacttta gtttttgatg taattgtatt
    37021 aattctgttc tcatttgatt tcttaattta gcatctaaat ttgacaatgg ttcatccatt
    37081 aaaaatacct ttggattttt aaccatagct ctagcaagtg ccactctttg tctttgacct
    37141 ccagataagt tgcctggttt cacatttaaa tattctctca atcctactac atcaataact
    37201 tctgttataa gtttttctct tttttctttt tctacttttt tgtttttaag accaaattct
    37261 atgttttctc taacagtcat atgtggatat aatgcataat tttgaaatac catagctata
    37321 tcccttttac tagcatccgt ttttgtaaca tcattttctt caatcttcaa cctacctgaa
    37381 gttatatctt caagacctgc aatcattctt aacgtagtag atttaccaca tccacttggg
    37441 cctaccaata ctgtaaaaga accatcttct atagtaagat ttaaattttc tataactgta
    37501 ttttttttat tataagattt tgttacattt tctagtctta tatctgccat ttttatcctc
    37561 ccaaaatatt taatttaatt ctacgattta cttatagatt aataatactc ttaatttgta
    37621 aaggatatat taagacaaag tgaatatatg gtaaacttat taaaataaag gttaaattat
    37681 aaacattttt tgttaaatat actgaagtta agatgatata cagcttatgt tagctataat
    37741 tttctatatt tttcatattc atggtttgct atcacaatgt aattttaatt tatgaagagt
    37801 catataaaac tatttatttt ttatataatt tggtttgaaa gtaaaaaaga cctctatggg
    37861 ggatagaggt ctttaagtgg gggagattga gtaatttatt tttgctatat taagttttac
    37921 aattatatta tgtcccaaat ttacaaggtt taaacataaa aaataaaaat tttttaattt
    37981 ttataaattt acc
//
LOCUS       DAYAOO010000036        35983 bp    DNA     linear   BCT 12-OCT-2024
DEFINITION  TPA_asm: Clostridioides difficile isolate ST8-SSI-h139-18
            SAMN40601845-rid21577343.denovo.036, whole genome shotgun sequence.
ACCESSION   DAYAOO010000036 DAYAOO010000000
VERSION     DAYAOO010000036.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN40601845
            Sequence Read Archive: SRR28438827
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 35983)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 35983)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-MAY-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-MAY-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002157583.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002157583.1
            Genome Coverage       :: 163x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/11/2024 16:19:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 4,038
            CDSs (total)                      :: 3,963
            Genes (coding)                    :: 3,930
            CDSs (with protein)               :: 3,930
            Genes (RNA)                       :: 75
            rRNAs                             :: 6, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 60
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 33
            CDSs (without protein)            :: 33
            Pseudo Genes (ambiguous residues) :: 0 of 33
            Pseudo Genes (frameshifted)       :: 7 of 33
            Pseudo Genes (incomplete)         :: 25 of 33
            Pseudo Genes (internal stop)      :: 11 of 33
            Pseudo Genes (multiple problems)  :: 8 of 33
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..35983
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN40601845-rid21577343.denovo.036"
                     /isolate="ST8-SSI-h139-18"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Denmark"
                     /collection_date="2018"
                     /collected_by="Statens Serum Institute"
     gene            137..973
                     /locus_tag="ACGI5H_001997"
     CDS             137..973
                     /locus_tag="ACGI5H_001997"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438284.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="AraC family ligand binding domain-containing
                     protein"
                     /protein_id="HFG9697700.1"
                     /translation="MRQEERTVCFDRELKIEAYRFKGIMQKFPNHFHEHYVIGFIEKG
                     QRYLSCKNKEYTTSTGDLLLFNPFDSHTCEQIDDKVLDYRCINIKPEIMKKTVFEITG
                     KNYLPKFNQPVIFRSELVPLLQELHYIIMEEELDFKKEELFFFLIEQLIEEHTEPNLQ
                     SNLENTNIEIQAVCDYLENNYAEHIVLDELSTIAGMNKYSLLRNFTKLKGITPYRYLE
                     NIRVNKAKKLLEKGVEPIDAAIQTGFVDQSHFTNFFKNFIGLTPKQYQNIFINDDSNN
                     FK"
     gene            994..1416
                     /locus_tag="ACGI5H_001998"
     CDS             994..1416
                     /locus_tag="ACGI5H_001998"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889078.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2000 domain-containing protein"
                     /protein_id="HFG9697701.1"
                     /translation="METKNSKCVMVIDENLPMGIISNTAAIMGITLGKHAPETVGPDV
                     IDKTGNSHLGIIDIPVPILKGNKEIIKDLRKKLYTLEFNDLTVVDFSDVAQSCNLYEE
                     FTQKIASVPEDELQYFGIAIYGNKKKVNKLTGSMPLLR"
     gene            complement(1627..2790)
                     /locus_tag="ACGI5H_001999"
     CDS             complement(1627..2790)
                     /locus_tag="ACGI5H_001999"
                     /EC_number="3.4.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419435.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008236 - serine-type peptidase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanyl-D-alanine carboxypeptidase family
                     protein"
                     /protein_id="HFG9697702.1"
                     /translation="MKKLASTALAILIALTPLSFSFANNKENADANQLNISSKSAILM
                     DVGSGQILYEKDAHKKLPPASVTKVMTMLLIVEALDSGKIKLDDEVQVSETASSMGGS
                     QIFLEPGETQKVDTLLKGIAVASANDACVAMAEHLAGSVEGFVDRMNAKAKELNMNDT
                     HFANTNGLPVANHYTSAHDIALMSRELLKHEMISKYLTTWMDKVVVGKKQVTVGLANT
                     NKLIKHYQGATGVKTGFTQEAKYCLSASAKRGNTHLVAATLGAETSPERFNDASSLLN
                     YGFANYESVKLCSKGDNIATLTLDKADENKVKLVAKEDLNALIKKGSSKEFEKKIEIV
                     KNPKMPIKKGTVLGKIKICKDKKVIGEVELINTKDINKASYLQMLQRIIDNMI"
     gene            complement(2844..3044)
                     /locus_tag="ACGI5H_002000"
     CDS             complement(2844..3044)
                     /locus_tag="ACGI5H_002000"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428269.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CD1290 family small acid-soluble spore protein"
                     /protein_id="HFG9697703.1"
                     /translation="MDDVSRQNAIKALKQTKMEIAGEYGMNYEDAFEIIENASNKGVL
                     EGYFKKLEKKKNLGQGISRHLE"
     gene            complement(3250..4926)
                     /locus_tag="ACGI5H_002001"
     CDS             complement(3250..4926)
                     /locus_tag="ACGI5H_002001"
                     /EC_number="3.1.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861169.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0004540 - RNA nuclease activity [Evidence
                     IEA];
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease J"
                     /protein_id="HFG9697704.1"
                     /translation="MQLFKKNTNKIKVMALGGLNEVGKNMTVVEYKDEIIVIDAGLSF
                     PEDEMLGVDIVIPDITYLVKNRDKIKGIFITHGHEDHIGALPYILKKINVPVYGARLS
                     IGLIQVKLKEHKMNNVKLNVIGPRQVIKLDNMEVEFLKNNHSIPDAYSIAIHTDQGII
                     YHTGDFKIDLTPIDGDVMDMHRICELSKKGVLLMLADSTNAEKPGFTMSEKTVGVGLD
                     ELFAKGNGRRIIVATFASNIHRLQQIINTAEKFNRKVAISGRSMVNVVGVAKELGYLD
                     ISDDMLIDLNDICKYEDSELVIITTGSQGEPMSALARMAFSEHKKVEIKSGDLVIISA
                     HPIPGNEKLISRVINFLFEKGAEVVYSDIADIHVSGHACQEELKLIHALVRPKFFMPA
                     HGEYRMLKRHAEIAEQLGMDKENIFVMQTGDVLELDKNSAKVANRIQTGNILVDGLGV
                     GDVGNIVLRDRKHLSEDGLMIVVVTISKDEGKVLAGPDIISRGFVYVRESEDLMDGAK
                     DIIKNVLNECEEKNIKEWAYLKNNIKENLKEYLYQKTKRNPMILPIIMEV"
     gene            5143..5880
                     /locus_tag="ACGI5H_002002"
     CDS             5143..5880
                     /locus_tag="ACGI5H_002002"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428273.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="metal-dependent hydrolase"
                     /protein_id="HFG9697705.1"
                     /translation="MRGKTHCAIGILTAIQTSLIFKIPISLVDILVSATFAVLPDLDK
                     SNSMVSNFILKNNVSKYIYRIFIYAVNIIIFFISININDNFYLSAIITFVAIIIIEAK
                     LTHTFLRKVFLSLIFILLAICLYIIEVEIYFTIFCLMLSIFPWLKHRSFSHSIFATII
                     VYFLLKQIELITNINNLSFYGTIGYASHMFLGDLFTKQGIPIFYPLSEKKISLGFLTV
                     GGPFSNFIEKSFIFVLIGLIIFSILKL"
     gene            complement(5997..6455)
                     /locus_tag="ACGI5H_002003"
     CDS             complement(5997..6455)
                     /locus_tag="ACGI5H_002003"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419428.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Fur family transcriptional regulator"
                     /protein_id="HFG9697706.1"
                     /translation="MANTMDLLKDKLKETGFKITPQRRAIVEILLKHDHSHLSSEEIY
                     DLVRVDCPEIGLATVYRTMQLLDEIGLISKLNLDDGCIRYEISLHKEDCHNHHHLICK
                     NCGKIMEAKEDLLDNIEKEIQSLYKFKILDHDVKFYGLCDECNGVSDSEE"
     gene            complement(6737..7024)
                     /locus_tag="ACGI5H_002004"
     CDS             complement(6737..7024)
                     /locus_tag="ACGI5H_002004"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1292 domain-containing protein"
                     /protein_id="HFG9697707.1"
                     /translation="MEENIINLIDENGVESQFEIILTLEAEGKEYAILMPLDDEEAEE
                     ALIFRIDEDEEGEILIPLESDEEYETVVAVYTAIMEEEGLNYDEDESNGLN"
     gene            complement(7102..7527)
                     /gene="ruvX"
                     /locus_tag="ACGI5H_002005"
     CDS             complement(7102..7527)
                     /gene="ruvX"
                     /locus_tag="ACGI5H_002005"
                     /EC_number="3.1.21.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428279.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0006364 - rRNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction resolvase RuvX"
                     /protein_id="HFG9697708.1"
                     /translation="MLDGRIMGLDVGDKTIGVAVSDLMGLTAQGVKTIKRVGKKKDIE
                     ELKAIIKEKQVNKIVSGLPKNMNGTLGPQGEKVIKFCELVKAETGIDVEFWDERLSTV
                     AAERSLLEADVSRQKRKKVIDMLAAVIILQGYLDFKINS"
     gene            complement(7733..9904)
                     /locus_tag="ACGI5H_002006"
     CDS             complement(7733..9904)
                     /locus_tag="ACGI5H_002006"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428282.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9697709.1"
                     /translation="MRKKIMSLFAIVIMIFVSTASYGFAEEKGKVIFIDMNRTNLGSM
                     MNIPILKNEIEKRGYVALMNIRGDQGTDDRRSYASMGAGTRASVTTEDYINFQKVDQD
                     TAKAFEVATGQKAKEINDLGINRSINENLEYGEYGANLGSLGKTLSENGLKTSVIGNA
                     DIIENNQLVKNRNLCLVAMDQYGRIDSGNIDNINKKDSKMPFGISTDYDKLLDETKKS
                     YKNSDAIFVELGDTYRLDMYRLNLNDNTYDIMKKNIVKNINKYLEQVFSMVGENDTVY
                     IASAFPSDLDYKNKRRLSPIIKFSGEGKGLLESATTRKAGIVANLDVGVDILGTFGLE
                     NKEMVGRSYTLVNKEDNISYLKSLYERIVSISSIRSTIINGFVGVISASWVIAMFAIF
                     FRNYMPHKERVFKVLKEFIKLGIIMPLSFMLAPLMNFKTPISISLGIFATTLILYLLG
                     RKLFKDNDIKHMGFFATLTILVIVIDSVFGTYLMQNNIMSYDAVIGARYYGVGNEYEG
                     VTIASAVFGLAVLLHYKKVSKLLVVIFSLIILITSAYPSMGANVGGAISECVAYLLFI
                     MLIYDIKIDFKKAVLLAVSAVVVVFAFAALDILSGSESHLGMFVQRIFLNGPGEILQT
                     FGRKIQMNMQLAQTSVWVNILLVGIGVIAVLIFKPSRHFRKIMNNFPILFKGFIASMV
                     GCIITLLVNDSGIVAASTASIYILIPLIIISINMIIFEKNN"
     gene            complement(9914..10171)
                     /locus_tag="ACGI5H_002007"
     CDS             complement(9914..10171)
                     /locus_tag="ACGI5H_002007"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419418.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IreB family regulatory phosphoprotein"
                     /protein_id="HFG9697710.1"
                     /translation="MEKDLDYTMKFEGIPEDRMSVGDTIDFVYKALVEKGYNPINQII
                     GYLLSGDSSYITSHKNARAIIKKFERDEILEEVITHYLNRK"
     gene            complement(10196..12835)
                     /gene="alaS"
                     /locus_tag="ACGI5H_002008"
     CDS             complement(10196..12835)
                     /gene="alaS"
                     /locus_tag="ACGI5H_002008"
                     /EC_number="6.1.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428286.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0004813 - alanine-tRNA ligase activity
                     [Evidence IEA];
                     GO_process: GO:0006419 - alanyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="alanine--tRNA ligase"
                     /protein_id="HFG9697711.1"
                     /translation="MEKMGLNEIRSKFLEFFESKGHYVANSYSLVPNNDKSLLLINSG
                     MAPLKNYFSGVEVPPSVRMCTSQKCIRTGDIENVGITARHATFFEMMGNFSFGDYFKR
                     ESIKWGWEFVTEWLNIPEDKIWVTVYEEDDDSYDIWAKEMNFPEERMVRLGKDDNFWE
                     IGTGPCGPCSEIYFDRGEEYGCDNPDCKPGCDCDRYLEFWNHVFTQFDRDEEGNYSLL
                     ENKNIDTGMGLERMGCIMQGVDTIFEVDTIKSILEAVEKLTGVKYGENPKNDISIRII
                     TDHIRAVTFLVSDGVLPSNEGRGYVLRRLLRRAARHGKLLGVKELFLQKLIDEVIKVN
                     DKAYPVLVEKESYIKKVVGIEEEKFNETIDQGTEILNSYIEVLKNEGKTVLSGQEAFK
                     LYDTYGFPIDLTKEILEEEHLSVDEEAFNEEMEKQKERARNARGNMDGESWKEDPLSK
                     LESTVDSTFNGYSEIYGEGTIEAIVKDDELVQSAEEGDKVSIVLDNTTFYPEGGGQVG
                     DCGLITNENLVLEVLNTKKGANNSIKHIGIIKSGRISNGDKVKTLVDRETRMSAARNH
                     SATHLLHKALREVLGEHVNQAGSLVTPERLRFDITHFEAISNEELKVIEEKVNNVILS
                     SLDIKCDIMNIKEAKEKGATALFGEKYGDEVRVVSMGDYSTELCGGTHLTNTSQVGMF
                     KILSEGGVAAGVRRIEAITGKAVYEYLKERDGIISEVCVNLKSKEDNLIQRISSLLEE
                     NKNLSKELHDMKAKMSLQSVDSIFDSKVEVNGVNLITNKFEGMDMDTLRETADNLRDK
                     LGSGVVVLANVVDDKVNFVVTATKDVLDKGIHSGNIVREVAKIAGGKGGGRPNMAQAG
                     ASDVSKVDQALSYASEVIKTQVK"
     misc_binding    complement(12903..13141)
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            complement(13284..14363)
                     /gene="mnmA"
                     /locus_tag="ACGI5H_002009"
     CDS             complement(13284..14363)
                     /gene="mnmA"
                     /locus_tag="ACGI5H_002009"
                     /EC_number="2.8.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438277.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016740 - transferase activity [Evidence
                     IEA];
                     GO_function: GO:0016783 - sulfurtransferase activity
                     [Evidence IEA];
                     GO_process: GO:0008033 - tRNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA 2-thiouridine(34) synthase MnmA"
                     /protein_id="HFG9697712.1"
                     /translation="MNKKVMIGMSGGVDSSVAAYLLKQQGYDVIGVTMKLWQDDDVVE
                     IEGGCCSLSAVEDARRVANKIGIPFYVLNFREVFKEKVIDYFIDEYLEGKTPNPCIAC
                     NKHIKFDDFYKKARQIGCDYVATGHYAKIEKDESTGRYLLKKSVTDKKDQTYALYNLT
                     QEQLEHTLLPIGDYEKDRVREIAKEMGMAVHNKPDSQEICFVKDNDYANYVKKHSKKR
                     IEEGFFVDTKGNILGKHKGILYYTIGQRKGLGITFGKPMFVIDINPINNTIVLGDNED
                     LFKKELIAKDVNFISIDTLEEPLRVQAKIRYSAKPSPATIHRVGEDTIKIVFDEAQRA
                     ITKGQSVVMYDGDIVVGGGIIEKSL"
     gene            complement(14652..15092)
                     /gene="nifU"
                     /locus_tag="ACGI5H_002010"
     CDS             complement(14652..15092)
                     /gene="nifU"
                     /locus_tag="ACGI5H_002010"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902397.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005198 - structural molecule activity
                     [Evidence IEA];
                     GO_process: GO:0016226 - iron-sulfur cluster assembly
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Fe-S cluster assembly scaffold protein NifU"
                     /protein_id="HFG9697713.1"
                     /translation="MQYSDKVMEHFMNPRNMGEIDNASGVGEVGNPTCGDIMKIFLDI
                     DGDVIKDVKFKTFGCGSAIASSSMATEMIKGKTIKDALELTNKAVAEALDGLPPVKMH
                     CSVLAEQAVKAALIDYAQKNNIHIPELDGYVIDDAHDHDVEEEE"
     gene            complement(15146..16339)
                     /gene="nifS"
                     /locus_tag="ACGI5H_002011"
     CDS             complement(15146..16339)
                     /gene="nifS"
                     /locus_tag="ACGI5H_002011"
                     /EC_number="2.8.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861166.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA];
                     GO_function: GO:0031071 - cysteine desulfurase activity
                     [Evidence IEA];
                     GO_process: GO:0006520 - amino acid metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine desulfurase NifS"
                     /protein_id="HFG9697714.1"
                     /translation="MEKRRLYMDYSATTPIKKEVLDAMMPYLTDYFGNASSFHTFGRE
                     AKDALDKAREQVAALINAEPSEIYFTAGGSESDNWTLEGVAYANKNKGNHIITSKIEH
                     HAILHTCEYLAKHHGFEITYLDVDSEGKVDLKQLEDSIKDTTILISIMFANNEIGTIQ
                     PIKEISEIAKKHKILFHTDAVQATGNIPVDVKELGIDLMSMSSHKIYGPKGVGALYIR
                     KGVRLHNFVHGGAQEKSKRAGTENIPAIVGYGKAAELAKENMQNHVETLTRLRNKLID
                     GVLERIPYTRVNGSLENRLPGNANFAFQFIEGEGILLLLDMLGIAGSSGSACTSGSLD
                     PSHVLLAIGLPHEIAHGSLRLTVGDFTTDDDIDYILENLPKVIERLRSMSPLYDDAKK
                     QGLVK"
     gene            complement(16357..16803)
                     /locus_tag="ACGI5H_002012"
     CDS             complement(16357..16803)
                     /locus_tag="ACGI5H_002012"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419409.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Rrf2 family transcriptional regulator"
                     /protein_id="HFG9697715.1"
                     /translation="MKLSTKGRYGLKAMFELALNQDNGPVSLKFIAKKQKISDQYLEQ
                     IFSSLKKSGLVKSVRGAQGGYLLSKNAEDITVGDILVVLEGPVALSDCVLDEDVCENS
                     NMCVTKIVWEKMKKGIEDVIDSITLKDMINDYNKNKLENDITNIKK"
     gene            complement(16912..17682)
                     /locus_tag="ACGI5H_002013"
     CDS             complement(16912..17682)
                     /locus_tag="ACGI5H_002013"
                     /EC_number="2.3.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419406.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016747 - acyltransferase activity,
                     transferring groups other than amino-acyl groups [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HFG9697716.1"
                     /translation="MIIKLNSTYHSRVMKYLKKEPEYNLFIIGDIERYGYGNNFLNIW
                     ADVGEHGEIKAILLKYFEFMMFYSDGEYDVEGFYNLLRNTNYEEISGKICAVDALAKR
                     LGLNNLKVVDFCKLQTKKFLIDNNCNAKVKRIRLGNLKKTVKLYDLIDEFHSTTLENL
                     KNGLRTGRGYCIEINKQVVSMAKSTSENRTHAMIIGVGTHPKYRAKGLATKCLIKLCS
                     ELLRENKIPCLFYDNEEAGKIYKKLGFENIGKWGIYSK"
     gene            complement(17713..18978)
                     /locus_tag="ACGI5H_002014"
     CDS             complement(17713..18978)
                     /locus_tag="ACGI5H_002014"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861165.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication-associated recombination protein A"
                     /protein_id="HFG9697717.1"
                     /translation="MPLADKIRPKTMNDVIGQSHIIGNGKILSKILQSNFLPNMIFFG
                     PPGVGKTTVAEIIAERSNKSFYKINATNSSLEDIKKVISELGSINNVNGVLLYIDEIQ
                     SFNKKQQQSILEFMENGSITLIASTTENPYHYVYKALLSRSTVFEFKPLEKLDIEKGL
                     KRAVEVLNEDSYMDIECNNDAIEDIAILSDGDMRRALNILEVVVYSTKPNKDNITYID
                     SDVIRASTFNKIINYDKNGDSHYDILSAFQKSIRGSDPQASIHYLARLIKGGDLISIC
                     RRLLVIASEDIGLAYPNAIVIVKACVDSAMQLGFPEAKIPLAEATILLATSPKSNSAC
                     IAIMKAMDELDKEFVKDIPNSIKDAHYSGSKEIGRGCGYKYPHNFKNHYVKQQYLPDS
                     IKDSIYYIPQENKTEKNIKKYLEYLNSDF"
     gene            complement(19085..19870)
                     /gene="codY"
                     /locus_tag="ACGI5H_002015"
     CDS             complement(19085..19870)
                     /gene="codY"
                     /locus_tag="ACGI5H_002015"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438268.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0045892 - negative regulation of
                     DNA-templated transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GTP-sensing pleiotropic transcriptional
                     regulator CodY"
                     /protein_id="HFG9697718.1"
                     /translation="MASEVLQKTRKINKTLQTSGGSSVSFDLLAGALGDVLSSNVYVV
                     SAKGKVLGLHLNDVQDSSVIEDEYTKQKKFSDEYTQNVLKIDETLENLNGEKILEIFP
                     EEHGRLQKYTTVVPILGSGQRLGTLVLSRYSNSFNDDDLVIAEYSATVVGLEILRAIG
                     EELEEEMRKKAVVQMAIGTLSYSELEAVEHIFAELDGKEGLLVASKIADRVGITRSVI
                     VNALRKFESAGVIESRSLGMKGTHIRILNDKLTDELKKLKNNQ"
     gene            complement(20035..22122)
                     /gene="topA"
                     /locus_tag="ACGI5H_002016"
     CDS             complement(20035..22122)
                     /gene="topA"
                     /locus_tag="ACGI5H_002016"
                     /EC_number="5.6.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892959.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003917 - DNA topoisomerase type I (single
                     strand cut, ATP-independent) activity [Evidence IEA];
                     GO_process: GO:0006260 - DNA replication [Evidence IEA];
                     GO_process: GO:0006265 - DNA topological change [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type I DNA topoisomerase"
                     /protein_id="HFG9697719.1"
                     /translation="MAKTLVIVESPAKAKTIEKFLGKSHYTVKASVGHVRDLPKSKLG
                     VDIENNFEPQYINIRGKGDVIKELKKEAKKSKQVYLATDPDREGEAISWHLAHILNLD
                     ESEDCRIEFNEITKDAIKKAIKHPRNIDINLVDAQQARRVLDRLLGYQISPILWQKVR
                     KGLSAGRVQSVTTKLICDREKEIKAFIPKEYWTIDVEAKTVKDKDITLKFYGKNDEKI
                     ELENEEAVNEILKEMEGKDLKVEKIESKSRRKSAPKPFTTSMLQQEGANKLFFTTKKT
                     MMIAQELYEGIDIEGEGTVGLISYIRTDSKRISDEAKEKAKGYIVNNLGENYYKNIGD
                     KKEKKDTKKVQDAHEAIRPTSVDRTPESIKASLSKDQYKLYNLIWRRFVASQMEDSVF
                     DILNVECKIGDIVFKATGSKMKFDGYTKVYNFSEREDKILPSIEKGDILNIENILPDQ
                     HFTQPPARYTEASLVKTLEELGIGRPSTYAPTIATILNREYVEKQGTSLCPTELGIIV
                     TDILENNFHKFIDVDFTADMESKLDVIEEGNTDWKKIVSESYAPLKEAIEEALENIEK
                     VNMDEETDEICENCGSNMVIKYGRFGKFMACKNYPDCKTTRPIMNKIGVKCPKCEEGD
                     IILRKSKRGKAFYGCSNYPNCDFVAWNKPTGEFCEKCGSYMVEKVTKSETKTVCSNKE
                     CNKETKEHNDGKE"
     gene            complement(22155..23255)
                     /gene="dprA"
                     /locus_tag="ACGI5H_002017"
     CDS             complement(22155..23255)
                     /gene="dprA"
                     /locus_tag="ACGI5H_002017"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438264.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0009294 - DNA-mediated transformation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-processing protein DprA"
                     /protein_id="HFG9697720.1"
                     /translation="MEKRDTYLWLKSIGGITTKTIEIIENEIVNIEDIFDFSEKEIYN
                     LKNISLNIRKNIVKYRGHAYLENIKELLYKKAIKYICKYDKEYPENLKNIYNAPKLLF
                     YKGDIGLVNNNFNIAIVGSRKPTAYGINCAKTISCQLSQYGVNIVSGLAIGIDAYSHI
                     GCMSGKSKTIAVLGSGVDNPLPKQNLHLSNKILENGGLLLSEYNINSTVAPYHFSNRN
                     RIISGLSDGVVVVEAAIKSGALITVDFALEHGKNVFAIPGNINSQMSRGCHKIIKEGA
                     KLIENIDDILNEYNIFNIIDKKINQKYDNISLNAKSKQIIEAIKREGNLHIDSICDYT
                     GIEIKYVNSIINELVLNELVVEMNNKTYSLNV"
     gene            complement(23274..24875)
                     /locus_tag="ACGI5H_002018"
     CDS             complement(23274..24875)
                     /locus_tag="ACGI5H_002018"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729548.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="YifB family Mg chelatase-like AAA ATPase"
                     /protein_id="HFG9697721.1"
                     /translation="MLSIINSSNLVGIDSFLVKVEVDVSNGIPSFNIVGLPGKEIKEA
                     RERVKSAILNSGYKFPSTRIVVNLSPADIKKEGAFLDLSISIGLLRELIKKDENYIRE
                     SMFIGELSLDGKIRKVRGILPIIMGAKTQNIKRIFIPIENIKESLFVDEIDIIPIKSL
                     KECVDFLNEEIKVDKVRIMSFLDDKSRKENEELEKDNSYIDCKYTKINNEESKYDEDF
                     KDVKGNYFVKRSAEIAAAGNHNMFMIGPPGSGKTMIAKRVRTILPDISVEEMIEVSKV
                     YSILGMINETKGIIDKRPFRAPHHTTTKQSLIGGGMDARPGEIALAHRGILFLDEIAE
                     FDRKILETLRQPIEDGYVNISRVKYSAKYPCRVLLVAAMNPCPCGYYMSETECRCRSN
                     EIDRYINKISGPLLDRFDIFVEVNSIKYSDFNSLKQEESSQKIKRRVENARKIQINRF
                     KKDNIKNNSEIKAYNLFKYCKLEKEASKTAEMIFSKYNLSSRSYTKLLKMARTIADLE
                     ERDLINSQCIIEAFSFRKAYYSYFK"
     gene            complement(24906..25250)
                     /locus_tag="ACGI5H_002019"
     CDS             complement(24906..25250)
                     /locus_tag="ACGI5H_002019"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003676 - nucleic acid binding [Evidence
                     IEA];
                     GO_function: GO:0004518 - nuclease activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="YraN family protein"
                     /protein_id="HFG9697722.1"
                     /translation="MNNKEKGDFGEKVAVNYLLSKGAKILEKNYRLKIGEIDIIAKME
                     DEIIFVEVKSRSNIKFGYPCESVSFKKRKKIIGVANYYIIKNNLNNTPIRFDVIEVYL
                     LEKRINHIMNAF"
     gene            25434..26597
                     /locus_tag="ACGI5H_002020"
     CDS             25434..26597
                     /locus_tag="ACGI5H_002020"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428307.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000155 - phosphorelay sensor kinase
                     activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HFG9697723.1"
                     /translation="MNREKLVAFIRYLSLFILVVSYLKNVENTLYPVITMIILFLIII
                     NNQVRFFSLSNENKFILISYFLELILIFILCNYTKTFNSIYFVPLILDISFLIKEKYK
                     YILFSFVIISSLIISLDKNIYLALESSSILLIITVLSIYIENENLSKLYSQNLYDKLR
                     ISKDELKKVNADLETYASSIEELAILKERNRISREIHDSVGHSLSTTIIQLNAIEKLL
                     KDKPLIYDLVHELREFVTESFQDVRRAISELKPVEYENYQSLFKIKELVKSFIKLTNI
                     NVKLTISKNTWNLSRNQSIALYRLIQESLSNSSMHGKATEIRIFITFNTSNLIITISD
                     NGIGCGNIKKGNGLNSINERIYELNGKVEFDNSNNGFTIRASFPKFSGGDFFE"
     gene            26590..27237
                     /locus_tag="ACGI5H_002021"
     CDS             26590..27237
                     /locus_tag="ACGI5H_002021"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905386.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator"
                     /protein_id="HFG9697724.1"
                     /translation="MNKIKVLIVDDEKLIRKGLKIILSSYNDLEIVGDASNGYEALEF
                     CKMNDVDIVLMDIRMKVCDGVLGTRLIKEYNNSITLLILTTFNDDEYIKDAMKFGASG
                     YLLKDSSDEVLHEGIRSSFFGNIVLDKSVAEKIMTSEKTIKQEHLYDMYNLTEKEISI
                     IRLIANGLNNKEISQELFLSEGTIKNNITNILAKLELRDRTQLAIFAFKNKIVIE"
     gene            27366..28301
                     /locus_tag="ACGI5H_002022"
     CDS             27366..28301
                     /locus_tag="ACGI5H_002022"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729545.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HFG9697725.1"
                     /translation="MDIVRVNNITKRFNDKLVLDNISFSVKKGEIFGLIGPNGAGKST
                     LINIITNLMLPNSGSIQINGLDLSKDYIKAKSIIGLVPQELAIIETLTPFDNLEYFGA
                     FYGLKGKLLKERIIEALEVTGLTEVKKKKVKKLSGGMQRRLNIGIALLNHPKILILDE
                     PTVGVDPQSRNHIFNFIKDISKKHETTVIYTSHYMEEVEHLCSKIFIMDEGKEIAFGN
                     NDYLKSLVSTNTKLIMEIKNINAQLIFDLKNTKGVISVLENNSLLELDIDKKLQLTDI
                     LSVIDKNNSKIMKISYEEPSLEDVFLNLTGKNLRD"
     gene            28315..29412
                     /locus_tag="ACGI5H_002023"
     CDS             28315..29412
                     /locus_tag="ACGI5H_002023"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896177.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HFG9697726.1"
                     /translation="MKLYMSVKTMLKSLKSSFILNLIYFLALPLILSWFLGMVTESMF
                     QNPIKTESTPIVIYDKDNTRLSNDLTKYLKNDLSYILTVKKDDSKAELKLTIPKGYES
                     SLLNEKSNTLNIEKLGTRDDIAILLQDILDTYHEKFYLNNSQKISSEDFSKLFNKNSI
                     DTSIINNNVKQSSYEYFALVSLGFLVIIFIMNNILSNYISESKGLSKRLYSMPITRVQ
                     FLIYDFVGLWIYSFIFLLLYVLFFRILGITFKGNFAILLLLCALSSYFMTSISTFVTS
                     FFSKKYGTAIVYALLFLQTIFGGIFSMISDTFTKLTSLSPTYLIGELFSNYETFKTID
                     SIGNLIFTCLIISTILIALAIVKEKYKWREV"
     gene            29415..30479
                     /locus_tag="ACGI5H_002024"
     CDS             29415..30479
                     /locus_tag="ACGI5H_002024"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018112789.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HFG9697727.1"
                     /translation="MIRLTIANIKRYLKNHTLLINMVMLPIILIFSLNFFINNSGNQS
                     MYFSPVAIVSDSSGKYEHKLINSSKLKENSFRLNEQDKAMNLLKNNKVSAVFVLDKNF
                     SNSIDKLQRPVVKCFKIENGGGSLWAESQIESFITKSLKLKVDKNIDDKLTKTNIIDN
                     KPDKNKGSFLVVFLICYFMYINAAHLASDLFTLKKSNVLKRLISTDNKDIKIIFSIFL
                     GLFFIQSIVYTFALLCFSIIEDFNLSLNVLMIVLANSFVSTGFVFWVARVFKNESSIS
                     LISTFYSLIGLAISISSLIPSMDKLSFMTNLSKFTPFYWTIDAIKNNGSILINIIALI
                     LIGIIFVTAGSLKLRDFAKN"
     gene            30723..31220
                     /locus_tag="ACGI5H_002025"
     CDS             30723..31220
                     /locus_tag="ACGI5H_002025"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419372.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CarD family transcriptional regulator"
                     /protein_id="HFG9697728.1"
                     /translation="MYKIGESVMYPKEGACSVNDIVTKKINHEMQKYYELSVIFNSNL
                     KISIPVLNADRIGIRPVMDGNDVDNFIQSINKTDGVWIFDRKERLKLYQDKFHSGDVF
                     EIVKLIKMLMIQDSSKQLCSTDKEFLNKAQKFALSELAAAQCKSYTMVLEEMKKHILN
                     SKNTN"
     gene            complement(31396..31644)
                     /locus_tag="ACGI5H_002026"
     CDS             complement(31396..31644)
                     /locus_tag="ACGI5H_002026"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419369.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9697729.1"
                     /translation="MSRKAYEEALVELEKFIDERKEIIKSAEDCIDKYIVDRTLPFDY
                     KDKCVEWQQELLDIAEAQVLEANELSVLLQEKKELEED"
     gene            complement(31710..32726)
                     /locus_tag="ACGI5H_002027"
     CDS             complement(31710..32726)
                     /locus_tag="ACGI5H_002027"
                     /EC_number="1.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889040.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0010181 - FMN binding [Evidence IEA];
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-hydroxy-acid oxidizing protein"
                     /protein_id="HFG9697730.1"
                     /translation="MEYNELLKSARENLNGSCKVCKVCNGVACAGEVPGMGGKGSGSS
                     FIENSKSLEKVKVNMRVIHDVSNPDTSIEMFGKKMSAPIFAAPVTGTTLNMGGKINER
                     DYIEPVVAGCVNSGIYAMVGDTAVDAFLMENLDVVKKYNGAGIVFIKPWDNENIIKKI
                     RLAEEAGAFAVGVDIDACGLVTLSLHGKPVLPKNVKQIKELVKSTKLPFILKGIMTVE
                     DALMAVEAGVDAIVVSNHGGRVLDCTPGACEVLPKIADAVKGKVTILADGGVRTGLDV
                     LKMIGLGADAVLIGRPFVTASFGGATDGVETYVNKLQSELSSSMILTGCQTIKDIDGK
                     VIYK"
     gene            complement(32784..33551)
                     /locus_tag="ACGI5H_002028"
     CDS             complement(32784..33551)
                     /locus_tag="ACGI5H_002028"
                     /EC_number="3.1.26.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729543.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0004523 - RNA-DNA hybrid ribonuclease
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease HII"
                     /protein_id="HFG9697731.1"
                     /translation="MQDKSVREIKEIIETLEVEKYMEYIELLRVDERKSVQGLAIKLA
                     KKLDNIRKEEERLETINIFENEGYDKGYLYIGGIDEAGRGPLAGPVVASVVVFKKDTK
                     IEGVNDSKKLSEAKRDELFEVIKEEALDYGIGIVNNEEIDEFNILNATYMAMKKAINC
                     LKKAPDYLLVDAATIPGIDISQNPIVKGDSKSISIAAASILAKVTRDSIMYQYDRVYP
                     EYGFKSHKGYGTKEHYEAIEKYGITPIHRKSFLKNIL"
     gene            complement(33619..35808)
                     /locus_tag="ACGI5H_002029"
     CDS             complement(33619..35808)
                     /locus_tag="ACGI5H_002029"
                     /EC_number="1.17.4.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428321.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0004748 - ribonucleoside-diphosphate
                     reductase activity, thioredoxin disulfide as acceptor
                     [Evidence IEA];
                     GO_function: GO:0031419 - cobalamin binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="adenosylcobalamin-dependent
                     ribonucleoside-diphosphate reductase"
                     /protein_id="HFG9697732.1"
                     /translation="MKYIIKRDGTKELFSKSKIEDAVYKASINSEGGVDRELAYGISR
                     KIANDYNSMEKCLSVEEIQDIVEVLLMESNRKDIAKHYILYRERRSEIRTKAWEFDEL
                     QKSIWKNKYRHNGESFDEWIKRISNNSSRISKLIRQKKFLFAGRILANRGLQKEGKKV
                     TYSNCYVIEPPKDSIEDIFDTAKKLARTFSYGGGVGIDISKLRPKGAKVNNAAKHTTG
                     AVSFMELYSMTTGLIGQRGRRGALMISMDVNHPEIEDFIDIKTDLEKVTKANISVRVT
                     DEFMQAVREKKLYNCTFEVETTGEKIVKIVNAYDLFNKFVKNNWDYAEPGILFWDKIK
                     TYNFMSEDKNFCFSGVNPCAEEPLPSGGSCLLGSINLSEFIIQPFGEHATFDINKLKS
                     CVREAVVALNDVLDEGLNLHPLQEQRDSVHKYRQIGLGVMGIADMLIKMGIRYGSDES
                     LELCDLIGKTMLNEAVKQSALIAKEYGTFSEYKYENISKSKFFIENLNEDTKEMVKKY
                     GLRNSQLLTIPPTGSISTMIGISGGIEPIFNLSYIRKTESLHDEDVYYKVYTPIVKEY
                     MDKKGITDEECLPDFFVTAMNIGYEERINMQKVWQKYIDASISSTINIPFETTVEDVF
                     NIYIKAWEAGLKGVTIFRDGCKRSGILINEKKEENNKEDKKENSKKEYYKNNKKEKDN
                     KDEKAKEIINKNFEGDEKFVCPECGSEGIAHTGGCSICLKCGYSGCN"
BASE COUNT        11524 a         6254 c         3902 g        14303 t
ORIGIN      
        1 atataataat tacacctact gtaagtgtaa tattatattg acatgaattg acattattgt
       61 ctcttagtca atattataca agaagtataa aaaaatatgt gttacacttt gtataacatg
      121 aaaggaggtt acctaagtga gacaagaaga acgcacagta tgctttgata gggaattaaa
      181 aattgaagca tatagattta aaggcataat gcaaaaattc ccaaaccatt ttcatgaaca
      241 ttatgtaatt ggttttatag aaaaaggtca aagatattta tcttgtaaaa ataaagagta
      301 taccacaagt actggagatt tgctactttt taaccctttt gatagtcata cttgtgaaca
      361 aatagatgat aaagtacttg attacagatg tattaatatt aagccagaaa taatgaaaaa
      421 aactgtcttt gaaattacag gtaaaaatta tttaccaaaa tttaatcaac ctgttatatt
      481 tcgcagtgag ctagtacctc tactacaaga attacactat ataatcatgg aagaagaatt
      541 ggattttaaa aaggaagagc tttttttctt cctaattgaa caattaattg aagaacatac
      601 agagccaaat ttgcaatcta acttggaaaa tacaaatata gaaattcaag cagtatgtga
      661 ttatctagaa aataattatg ctgaacatat agtacttgac gaattaagca ctatagcagg
      721 tatgaataag tactctctac ttcgtaattt tacgaaatta aaaggtatta caccatatag
      781 atacctagaa aatatacggg taaacaaagc taaaaagctt ttagaaaaag gcgtagaacc
      841 tatagatgct gcgatacaaa caggatttgt agaccaaagt cactttacaa acttttttaa
      901 gaattttatt ggtcttacac caaagcagta tcaaaatata tttataaatg atgattcaaa
      961 caactttaaa taaggtaaaa aggagaaata aaaatggaaa ctaaaaattc aaaatgtgtc
     1021 atggtaatag acgaaaattt accaatggga attatatcca atacagcagc tataatggga
     1081 attacactag gaaaacatgc cccagaaact gttggcccag atgtaattga caaaacaggt
     1141 aatagccact taggaattat tgacattcct gtacctattt taaaaggaaa caaagaaata
     1201 ataaaagatt tacgtaaaaa attatatact ttggaattta acgatttaac tgttgtagat
     1261 ttttcagatg tagcacaaag ttgcaatctt tatgaagaat ttacacaaaa gattgctagt
     1321 gttccagaag atgagttaca gtattttggg atagcaattt atgggaataa aaagaaagtg
     1381 aataaactta ctggtagtat gcctttactt agataattgt taaacaaccc tatatatgat
     1441 attaaatcaa atgatatttt aagatacata aacttttcta tatttctata aaaatcataa
     1501 gattataaaa tacttctata tggtaaataa aaatacccct atggcaaata attacataag
     1561 ggtatttttt atgtgtatta taatcatatc tttgtgtatt ataattatat ttcatctgat
     1621 aattatttat atcatattat caattattct ttgaagcatt tgtagatagc ttgccttatt
     1681 tatatcctta gtatttatca attccacttc gcctattact tttttatctt tacatatctt
     1741 tatttttcct aaaacagttc cctttttaat tggcatctta ggatttttta ctatttcaat
     1801 tttcttctca aattctttag aacttccttt tttaataaga gcatttaaat cttctttagc
     1861 aaccaattta actttgtttt catcagcctt atccaatgta agtgttgcta tattatcacc
     1921 tttactacat aacttaacac tttcataatt agcaaatcca taatttaaaa ggctagaggc
     1981 atcattaaat ctttctggag aagtctctgc tcctaaagtt gcagcaacta gatgagtatt
     2041 acctctcttt gcagatgctg ataaacagta ttttgcttct tgagtaaaac cagttttaac
     2101 accagttgct ccttgataat gctttataag tttattagta tttgcaagac ctactgtaac
     2161 ttgtttcttc cctactacaa ccttatccat ccatgtagtt aagtatttac ttatcatttc
     2221 gtgttttaat agttctctag acattaaagc tatatcatga gcagatgtat agtggtttgc
     2281 aactggaagt ccatttgtat ttgcaaaatg agtatcattc atatttaact cttttgcttt
     2341 agcattcatt ctatcaacaa atccttcaac acttccagct aagtgttcag ccatagcaac
     2401 acaagcatca tttgcagaag caacagctat accttttaat aatgtatcaa ccttttgagt
     2461 ttctcctggc tctaggaata tttgactacc acccatacta gatgcagttt cacttacttg
     2521 aacttcatca tcaagcttaa tcttgcctga atccaaagct tctactataa gtagcatagt
     2581 cattacctta gttacactag caggaggaag ctttttatga gcatcctttt catataaaat
     2641 ttgtccacta ccaacatcca tcaaaattgc tgattttgaa gatatattta gttggttggc
     2701 atcagcattt tccttattat ttgcaaaaga aaagcttaaa ggagtaagcg caattaatat
     2761 agccaaagca gtactagcta attttttcat cgatgtcacc tcttaaagtt tatttaaact
     2821 tattttctca catttaactt tttttattct aaatgcctag atataccttg acctaaattt
     2881 tttttctttt caagcttttt aaagtaacct tctaaaacac ctttattaga cgcattttct
     2941 attatttcaa aagcatcttc ataattcatt ccatactctc ctgctatttc catttttgtt
     3001 tgttttaaag cttttatagc attttgtctt gaaacatcat ccataagaat cctcctatca
     3061 gtaaaattta tatataagta gtttttacta ataaaagatt gttataattg gtattttatg
     3121 taatatatat ttttttaaaa tgagtattaa aaagacctct tgtaattctt aagataatat
     3181 caattggatt tctgatatta ctttaaaaat tacaagaggt ctaattttca aatttatagt
     3241 ttttttatat tatacttcca ttatgatagg aagtatcatt ggatttcgtt tagttttttg
     3301 atataaatat tcttttaggt tttctttaat attattcttt aaataagccc attctttaat
     3361 atttttctct tcacattcat ttagaacatt cttaattata tcctttgctc catccattaa
     3421 atcttctgac tctcttacat atacgaatcc tctggaaatt atatctggac ctgctaagac
     3481 cttaccctca tccttggaaa tagtaactac aactatcata agaccatctt ctgataaatg
     3541 ctttctatcc cttaaaacta tattacctac atcgcctact cctagaccat caactaatat
     3601 gtttcctgtt tgtatacggt ttgctacctt agcagaattt ttatctaatt ctaaaacatc
     3661 tcctgtttgc atgacaaaaa tattttcttt atccatacca agctgttcag ctatttcagc
     3721 atgtcttttt aacattctat attcaccatg agctggcata aaaaactttg gtctaactaa
     3781 tgcatgtata agttttaatt cttcttgaca ggcatgtcca gaaacgtgta tatcagctat
     3841 atcactgtat actacttctg ctcctttttc aaataagaaa ttgattactc ttgatattaa
     3901 tttttcattt cctggtattg gatgagcaga tattataact aaatcgccac tctttatttc
     3961 tacttttttg tgctctgaaa aagccattct agcaagagct gacataggtt caccttgtga
     4021 accagttgtt attatcacta attcactatc ttcatactta catatatcat ttaaatctat
     4081 aagcatgtca tcagaaatat ctaggtatcc taattctttt gcaactccaa ctacattgac
     4141 cattgagcga cctgatatag caacttttct attaaacttt tcagcagtat ttattatttg
     4201 ttgtaatctg tgtatgttgg atgcaaaggt agcaactata attcttctgc catttccttt
     4261 tgcaaataat tcgtcaagac ctaccccaac agtcttttca gacatagtaa atcctggttt
     4321 ttctgcatta gtactatctg ccagcattaa aagaactcct tttttgctca actcacagat
     4381 tctatgcata tccataacat ctccatcaat aggagtcaag tcaatcttaa aatctcctgt
     4441 gtggtatatt ataccttggt ctgtgtgtat tgcaatagag taagcatctg gtatactatg
     4501 gttatttttc aaaaactcta cttccatatt atcaagcttt ataacttgtc taggacctat
     4561 aacatttaac ttaacattat tcattttatg ttctttaagt tttacttgta taagacctat
     4621 actaagtctt gccccatata caggtacatt tattttcttt aatatatatg gaagagctcc
     4681 tatatggtct tcatgtccat gtgtaataaa tatacccttt attttatccc tattttttac
     4741 taaataagtt atatctggta taactatatc tactcctaac atttcatcct ctggaaaact
     4801 aagtccagca tctataacaa ttatttcatc tttatactca acaacagtca tattttttcc
     4861 aacttcgtta agtccaccca aggccattac ctttatcttg ttggtgttct ttttgaacaa
     4921 ttgcatcatc tccttctgtc tatttaattt tttaacacgt tctacaatca taaataatat
     4981 caaatcacgc actcgctacc agttattctt attgtaccat aattcgtatc atattttaag
     5041 ctatatttaa aatacattta acgtattatt ttgacaaacc tattttattt tgatatcctc
     5101 taaatattat atgatttaat atcggataat ttaggaggat ttatgcgtgg taaaactcat
     5161 tgtgcaatag gaatcttaac agctatccaa acatctttaa tatttaaaat tcctatatct
     5221 ttagttgata ttttagtttc agctactttt gctgtactac ccgatttgga taaatctaat
     5281 tctatggtct caaatttcat tctaaaaaac aatgtatcca aatacatata tagaattttt
     5341 atatatgctg ttaatattat tattttcttt atttcaataa atataaatga taatttttat
     5401 ttaagcgcaa taattacatt tgttgcaatt ataattattg aggcaaaact aacccacaca
     5461 tttctaagaa aagtttttct atcattaata tttatactat tagctatatg cttatacatc
     5521 atagaagttg aaatatattt tacaattttt tgtctaatgt tgtcaatttt tccctggtta
     5581 aagcacagaa gtttttctca tagcatattt gcaactataa tagtatattt tttactaaaa
     5641 caaatagaat taatcactaa tattaataat ttatcttttt atggtacgat tggttatgca
     5701 agtcatatgt ttttaggaga tttatttaca aagcaaggaa taccaatttt ttatccgcta
     5761 agcgaaaaga aaatttcttt aggtttttta actgttggag gaccatttag taatttcata
     5821 gaaaaatcat tcatttttgt acttatagga ttaattatat tttcaatatt aaaactataa
     5881 gcatcttgaa aactgtatat ttgcatttta tagatggttt ataataaaaa atggaagaat
     5941 agcatagaat ataaaagttc tatactattc ttccatcgac attaagcaat agaagtttat
     6001 tcttctgaat cgcttactcc attacactcg tcacatagtc cataaaattt aacatcatga
     6061 tcaagtattt taaatttgta caatgattgt atctcttttt ctatattgtc taaaaggtct
     6121 tctttagctt ccattatctt tccacaattt ttacaaataa gatgatgatg attatgacag
     6181 tcttctttat gtagactaat ctcatatctt atacatccat cgtctaagtt tagttttgat
     6241 attaatccta tttcatccaa tagctgcatt gttctatata cagtagctaa gcctatttca
     6301 ggacagtcaa ccctaactaa atcatagatt tcctcactac ttagatgtga atggtcatgt
     6361 ttaagcaata tttcaactat tgctcttctt tgtggcgtaa tcttaaaacc agtttctttt
     6421 aacttgtctt ttaataaatc cattgtattt gccataacat cacccttact attttcaatt
     6481 gataatcttt attaaataat attgtaattg ataattcatt ttttgtcaag acatttaaat
     6541 aaatttaatt tattctcata atataaatat atacccataa aagatatatt attcaccaaa
     6601 attcataaat tttttggtat ttttaataaa aaacaaaaaa acagatatat actataaatg
     6661 cttttacaat taataatgtt taattaaagc aaatataata aatatctgat ttttatatac
     6721 aaacttaatt acttatctag ttaagtccat ttgattcatc ttcgtcgtaa tttaaacctt
     6781 cttcttccat tatagcagta tacacagcta caacagtttc atactcttca tcactttcca
     6841 aaggtattaa gatttcacct tcttcatcct catcaattct aaagattaaa gcttcttcag
     6901 cttcttcatc atctaaaggc attaatattg catactcttt tccttctgct tctaatgtta
     6961 atattatttc aaattggctt tcaacgccat tttcgtctat taaatttatt atattttctt
     7021 ccataatgtc attcacctca aatttatttt tatttttatt atttatatta tatatcataa
     7081 gtattcaatt ttatagttct tttatgaatt tattttaaaa tctaaatatc cttgcaaaat
     7141 tattactgct gccaacatat ctataacctt ttttcttttt tgtctactaa catctgcttc
     7201 taataaagac ctctctgccg ctactgtaga aagcctctca tcccaaaact ctacatcaat
     7261 acctgtttct gcttttacca attcacaaaa cttgattact ttttctcctt gtggacctaa
     7321 agttccattc atattttttg gtaatcctga tacaatttta tttacttgtt tttcttttat
     7381 tattgctttt agctcttcaa tatctttttt cttgccaact ctttttattg tttttacacc
     7441 ttgtgcagtt aatcccatca aatcactcac agcaactcca atagttttat caccaacatc
     7501 aagacccatt attcttccat ctaacatagt tcctccttta tctatttata ttctatagat
     7561 taaatacata ttctgaacct ctcataacta aggtcacagg cttactgctt catataattt
     7621 tacataatca atcataaaaa ttgcaatatg attttttatg taagcatcca gtttacatta
     7681 ataatcatat tgcatttttt atttaaatcc tatatgaaca gtaaaaattt ttttagttat
     7741 ttttttcaaa tattatcata tttatactta ttattattag tggtataagt atatatatag
     7801 atgctgtaga tgcagcaact attccagaat cattaactaa aagtgtaatt atacaaccaa
     7861 ccatagatgc aataaaccct ttaaacaaga ttggaaaatt attcattatc tttctaaagt
     7921 gtctagatgg tttaaatata agcactgcaa ttactccaat tcctacaagt aaaatattta
     7981 cccatacact tgtctgtgct agttgcatat tcatttgaat ttttcttcca aatgtttgta
     8041 atatctctcc tggtccattt aggaaaattc tctgtacaaa catacctaaa tgagattcac
     8101 tacctgaaag tatatctaaa gctgcaaatg caaaaacgac aactacagct gaaacagcta
     8161 ataatacagc tttcttaaaa tctattttaa tgtcatatat aagcattata aacaacaaat
     8221 atgctacaca ttctgatata gctccaccaa catttgcacc cattgaagga tatgcactag
     8281 ttataagtat tattaatgaa aaaattacaa caagtaattt agataccttc ttataatgta
     8341 ataatactgc taagccaaat actgcacttg ctatagttac accttcatat tcatttccta
     8401 caccatagta cctagctcct atgacagcat cataactcat tatgttattt tgcattaagt
     8461 atgttccaaa tacagaatct ataactatga ctaaaatagt aagtgttgca aaaaatccca
     8521 tgtgctttat atcattgtcc ttaaataatt ttctacctaa caagtataat attagcgtag
     8581 ttgcaaatat tcccaaagat attgaaattg gagttttaaa attcatcaaa ggagctaaca
     8641 taaatgatag tggcattatt atgcctaatt ttataaactc cttaagtact ttgaatacac
     8701 gctctttatg tggcatataa tttctaaaga aaatcgcaaa catggcaatt acccaagaag
     8761 cagatattac gcctacaaag ccatttataa tagttgacct tattgaagat atagacacta
     8821 tcctttcata aagtgatttt agatagctaa tattgtcctc tttatttact aaagtataac
     8881 ttctacctac catctcttta ttttcaagac caaatgtacc tagtatatct actccaacat
     8941 ctaaattggc aacaattcca gcctttcttg ttgtggcaga ttccagtaga cctttccctt
     9001 ctccactaaa ttttattatt ggagaaagtc ttctcttatt cttataatct aggtcacttg
     9061 gaaatgcact tgctatataa acagtgtcat tttctccaac catagaaaat acttgttcaa
     9121 gatatttatt tatatttttt acaatatttt tcttcattat atcataagta ttatcattta
     9181 gatttaatct atacatatct aatctatatg tatctccaag ttctacaaat atagcatcac
     9241 tatttttata ggatttttta gtttcatcta gtaatttatc ataatctgta gatattccaa
     9301 atggcatttt agaatctttc ttattaatat tatcaatatt acctgaatca atccttccat
     9361 attggtccat agctactaaa cataagtttc tgtttttaac taattgatta ttttcaatta
     9421 tatcagcatt tccaattaca gatgtcttta aaccattttc tgataaagtt tttcctaatg
     9481 accctaaatt tgctccatat tctccatact caagattttc atttatagat ctattaatgc
     9541 ctaaatcatt tatttcttta gctttttgac ctgttgcgac ttcaaaagct ttagcagtat
     9601 cttggtctac tttttgaaaa ttgatatagt cttcagtagt tacactagct cttgttcctg
     9661 cacccatact tgcataagac cttctatcat cagtaccttg atcccctctt atattcatga
     9721 gagctacata gcctctcttt tctatctcat ttttcaagat tggaatattc atcatacttc
     9781 caagattggt cctattcata tcaataaata tgaccttgcc tttttcttca gcaaaaccat
     9841 agctagcagt tgatacaaaa atcataatga ctattgcaaa caacgacata atcttttttc
     9901 tcatttattt gacctacttt ctattcagat agtgcgtgat tacttcttca agtatctcat
     9961 ctctttcaaa ttttttaatt atagctcttg catttttatg actagttata tagctagaat
    10021 caccagaaag gagataccct ataatttgat ttatagggtt atatcctttt tcaactaatg
    10081 ctttatatac aaaatcaata gtatctccta cactcatcct atcttctggt attccttcaa
    10141 atttcatagt gtagtctaaa tctttttcca aactaaaaac ctccttgagt gaatgttatt
    10201 taacttgtgt cttaataacc tcacttgcat agcttaaagc ttggtcaacc ttagatacat
    10261 cactagctcc tgcttgtgcc atattaggtc ttcctccacc ttttcctcca gctatttttg
    10321 caacttctct aacaatatta cctgaatgta ttcccttatc taatacatct ttagtggcag
    10381 taactacaaa gttaacttta tcatctacta catttgcaag tactactaca ccagaaccaa
    10441 gcttatctct tagattatct gctgtttctc ttagtgtatc catatccata ccttcaaatt
    10501 tattagttat caaattaact ccatttactt caactttaga atcaaaaata gaatcaactg
    10561 attgtaaact catcttagct ttcatatcat gcaattcttt agataagttt ttattttctt
    10621 ctaataaaga acttattctt tgaattaaat tatcttcttt agattttaag tttacacaaa
    10681 cttcagagat aattccatct ctttctttta ggtattcata aacagctttt cctgttattg
    10741 cttctattct tcttacacct gctgctactc caccttcaga taatattttg aacattccta
    10801 cttgagaagt atttgtcaag tgagttcctc cacaaagttc tgtagaataa tctcccatag
    10861 aaactactct tacctcatca ccatattttt caccaaatag tgctgtagct cctttttctt
    10921 tagcttcctt tatattcata atatcacatt ttatgtctaa agatgataaa ataacattat
    10981 ttactttttc ttctattact tttaattctt catttgatat cgcttcaaag tgagtaatat
    11041 caaatctaag tctttctgga gttactaaag aaccagcttg attaacatgt tctcctaata
    11101 cttctcttaa tgccttatga agtaaatgtg tagcactgtg atttcttgca gctgacattc
    11161 tagtttctct atctacgagt gtcttcactt tgtccccatt acttattctt cctgatttta
    11221 ttatacctat atgttttata ctattattag cacctttttt agtatttaat acttctaaaa
    11281 ctaagttttc attagttatc aatccacaat ctccaacttg tcctccacct tcaggataga
    11341 aagtagtgtt atctagtact atagatacct tatcgccttc ttctgcactt tgaactagct
    11401 catcatcttt aactatagct tcaatagttc cttcaccata aatttcacta tacccattaa
    11461 atgtactgtc aactgtagat tctaattttg atagagggtc ttccttccaa ctttctccat
    11521 ccatatttcc tctagcattt ctagctcttt ctttttgctt ttccatttct tcattaaaag
    11581 cttcttcatc tacagataga tgttcttctt ctaatatttc tttagttaag tctataggga
    11641 agccataagt atcatatagt ttaaaagctt cttgaccact taggacagtc tttccttcat
    11701 tttttaatac ttctatataa gagttcaata tttctgttcc ttggtctata gtttcattga
    11761 atttttcttc ttctattcca actacttttt taatataact ttctttttca actaaaactg
    11821 gatatgcttt atcatttact tttataactt catctattag tttctgtaaa aataattctt
    11881 ttactcctaa taacttacca tgacgagcag cacgtctaag gagtcttcta agaacatatc
    11941 ctcttccttc atttgatgga agcactccat cactaactaa gaatgttaca gctcttatat
    12001 ggtcagttat tattcttatt gatatatcat tttttggatt ctctccatat tttactcctg
    12061 ttaacttctc aactgcttct agtatagatt taattgtatc aacttcaaag atagtgtcta
    12121 cgccttgcat aatacatccc attctttcaa gacccatacc tgtatctata ttcttgtttt
    12181 ctaatagact ataatttcct tcttcatctc tatcaaattg agtaaataca tggttccaaa
    12241 attctaaata cctatcacaa tcacagcctg gtttacagtc tggattgtca catccatatt
    12301 cttctcctct atcaaaatat atttctgaac aaggaccaca aggacctgta cctatttccc
    12361 agaaattatc atcttttcca agtctaacca ttctttcttc tgggaaattc atttcttttg
    12421 cccatatatc ataagaatca tcatcttctt catatacagt cacccatatc ttatcttctg
    12481 gtatatttag ccattctgta acaaattccc atccccattt tattgactct cttttaaagt
    12541 aatctccaaa tgagaaatta cccatcattt caaagaatgt agcatgtctt gcagttatac
    12601 ctacattttc tatatctcct gttcttatac atttttgaga tgtacacatt ctcacacttg
    12661 gaggtacttc tacacctgaa aagtagtttt tcaaaggtgc catacctgag tttataagta
    12721 acaaactctt atcattgttt ggtactaaag aataactatt tgctacataa tgaccttttg
    12781 actcaaaaaa ttctaaaaac ttacttctta tttcatttaa tcccatcttt tccatatcat
    12841 gttcctccta ataaatttta ttttttcgtt taaataaaaa acctcgtccc tataaataaa
    12901 tttatagggg cgaggacaat cgcggtacca ccctaattat catacaaagt atgatatctt
    12961 cggaaaacct tagctataac gtaactaccg tcaatctcta cttaaatctt ctttataaaa
    13021 gataaattgt tcaagattgc tactaaaagg ctgcttcaaa tatcatattc taagggcttc
    13081 cagcatttcc ctctctctgt aagacatcaa atattttact attccttatc actgtatttg
    13141 ttttttaatt aatatactaa ttatattact aaattttaca aaattaatca atactatatt
    13201 ttcatataca ataaatttat tttataaact ttatttactc ttaatatact ttattgctta
    13261 tttttttaat tttttagatg tttttataaa cttttctcga ttatacctcc acctactaca
    13321 atatctccat catacattac tacagattga cctttagtaa tagctctttg agcttcatca
    13381 aaaactattt taatagtatc ttctcctact ctatgaatag tagctggtga tggttttgct
    13441 gaatatctta ttttggcttg aactcttaag ggttcttcta acgtatctat tgatataaag
    13501 ttaacatctt tagcaataag ttccttttta aataaatctt cattgtctcc aagaactatg
    13561 gtattattta ttggatttat gtctattaca aacattggtt ttccaaaagt aattccaagc
    13621 ccttttcttt ggcctatagt ataatataat atacccttat gttttccaag tatattgcct
    13681 ttagtatcta caaaaaaacc ttcttcaata cgctttttag aatgtttttt tacataattt
    13741 gcatagtcat tatctttaac aaaacaaatt tcttgactat caggcttatt gtgtactgcc
    13801 atacccattt ccttagcaat ttctcttact ctatcttttt catagtcacc tattggcaat
    13861 aaagtatgct ctagttgctc ttgtgtaaga ttataaagtg cataagtttg gtctttttta
    13921 tctgtaacag atttttttag caaatatctt cctgtacttt catccttttc tatctttgca
    13981 tagtgacctg tagctacata atcacaacct atttgtctag ccttcttata aaaatcatca
    14041 aattttatat gtttattaca agctatacag ggattaggag tttttccttc caaatattca
    14101 tctataaaat aatctattac tttttcttta aacacttctc taaaatttaa aacataaaat
    14161 ggtataccta ttttatttgc tacccttcta gcatcttcaa cagcagataa agagcaacaa
    14221 ccaccttcaa tttcaacaac atcatcatct tgccacaact tcatagtaac accaatgaca
    14281 tcatatcctt gttgttttaa aagatatgca gctacagagc tatcaactcc tccactcata
    14341 cctatcatta cttttttatt cataaacaaa tttcacctca tcttttgcat tacttattat
    14401 tataccatat agagcaagta ttgtacttat ttaaaatata gcttgttcta ttttctaaaa
    14461 aaataatcat ctttattatt tgaatcttat ggattatttt gttaactaat taacctctaa
    14521 atcaagttaa aatacttaat ttaggcaata aaaaatagct attttaaaaa cagctatttt
    14581 ttatgtccta attatatcat tagtacttct ttttaatcat tgtaaacttc tcataacaca
    14641 atcacttatt tttattcttc ttcttcaaca tcatggtcat gagcatcatc tataacatat
    14701 ccatccaatt ctggtatatg gatattgttc ttttgagcat aatctataag agctgctttt
    14761 acagcttgtt cagctaaaac tgaacaatgc atctttactg gtggtaaacc atccaaagct
    14821 tctgcaacag ctttatttgt aagttctaat gcatctttta tagtttttcc ttttatcatt
    14881 tcagttgcca tagaagaact tgctatagct gaaccacagc caaatgtttt aaacttaaca
    14941 tcctttatta catctccatc tatgtctaaa aatatcttca ttatatctcc acatgtaggg
    15001 tttccaactt cacctacacc acttgcatta tcaatttctc ccatatttct tggattcata
    15061 aaatgttcca taactttatc actatattgc attatctttt cctcctactc aatttatgtc
    15121 tattttttat gctttatctt tatgtctatt ttactaaacc ttgtttcttc gcatcatcat
    15181 aaagtggtga catgcttcta agtctttcta ttacttttgg taagttctct agtatataat
    15241 ctatatcatc atctgttgta aaatctccaa ctgtaagtct taatgaacca tgtgctattt
    15301 catgtggtaa acctattgca agaagtacat gtgaagggtc taatgaacca gaagtacatg
    15361 cagaaccact tgaaccagca attcctaaca tatctaataa taaaagtatt ccttcacctt
    15421 ctataaattg gaatgcaaag tttgcatttc ctggcaatct attttctaag ctaccattta
    15481 ctcttgtgta aggtattctt tctaacacac catctattaa cttatttcta agacgagtta
    15541 aagtttctac atgattttgc atattttcct tagctaattc tgctgctttt ccatatccaa
    15601 ctattgcagg tatattttct gtaccagctc ttttgctttt ttcttgtgct ccaccatgga
    15661 caaagttatg aagtcttaca ccttttctta tgtataaagc tcctacacct tttggtccat
    15721 atattttatg tgaagacata ctcatcaaat ctattcctaa ttctttaaca tctactggaa
    15781 tattacctgt agcttgtact gcatcagtgt ggaataatat cttatgtttt ttagctattt
    15841 cggatatttc tttaataggc tgtatagttc ctatttcatt atttgcaaac attatactta
    15901 taagtatagt agtatctttt attgaatctt ctagttgctt taagtctact tttccttcgc
    15961 tatcaacatc taaataagtt atttcaaatc catgatgttt tgctaagtat tcacatgtat
    16021 gaagtattgc atggtgctct atttttgaag ttattatatg attacctttg tttttattag
    16081 cataagctac accctctagt gtccagttat cactttctga accacctgct gtaaaatata
    16141 tttcactagg ttcagcattt ataagggctg ctacttgttc tcttgcttta tccaaagcat
    16201 cttttgcttc tcttccgaat gtgtgaaaac tagatgcatt accaaaataa tctgttaggt
    16261 atggcatcat tgcatccaat acttcttttt taataggtgt tgttgcagaa taatccatat
    16321 acaatcttct tttttccatt acattcatct ccaaatctat tttttaatat ttgttatatc
    16381 attttctaat ttatttttgt tatagtcatt tatcatatct ttaagagtaa ttgaatctat
    16441 aacatcttct ataccctttt tcatcttttc ccaaactatt tttgttacac acatgtttga
    16501 gttttcacat acatcttcat ctagtacaca gtcagataat gcaactggtc cttctaatac
    16561 tacaagtata tctcctactg ttatgtcttc agcattcttt gaaagcaaat aacctccttg
    16621 agcacctctc acacttttta ctagacccga tttttttaaa gatgaaaata tttgttctaa
    16681 gtactgatct gatatttttt gcttcttagc aataaatttt aatgatactg gtccattgtc
    16741 ttgatttaat gctaattcaa acattgcttt tagtccatat ctacctttag tagacaactt
    16801 catatattat cacctctata tagaaatcta attcatactg ttttagtagg aattactttc
    16861 aagataattt tattataccc tactaatttt gtcaagatta attttaattt tttattttga
    16921 ataaattccc cattttccaa tgttttcaaa tcctagtttt ttatatatct ttccagcctc
    16981 ttcattatca taaaacaaac aaggaatttt gttttctctc agtaactctg aacatagttt
    17041 aattaggcat tttgtagcaa gtcctttagc tctatattta ggatgtgttc ctactccaat
    17101 tatcattgca tgagtcctat tttctgaagt actctttgcc attgacacca cctgtttgtt
    17161 aatctctata caatatcctc tacctgtcct tagtccattt tttaaattct ctaaagttgt
    17221 actgtgaaat tcatctatta agtcataaag ttttactgtc ttttttagat ttccaagcct
    17281 aattctctta acctttgcat tacaattatt atctatcaaa aactttttag tttgaagttt
    17341 gcaaaaatca actaccttta aattattaag tcctaatctc tttgctaaag catctacagc
    17401 acatattttc ccagatattt cttcgtaatt agtattacga agtagattat aaaaaccttc
    17461 aacatcatac tctccatcag aataaaacat cataaattca aaatatttaa gtaatattgc
    17521 ctttatttca ccatgttcac ccacatctgc ccatatattt aaaaaattat ttccatatcc
    17581 atatctttca atatccccta ttataaacaa attgtactca ggttcttttt ttaagtattt
    17641 cataactcta ctgtgataag ttgagttaag ttttataatc ataatatcta cccccgatac
    17701 ataaagttca gtctaaaaat cactatttag atattctaaa tattttttta tatttttctc
    17761 agttttattt tcttgtggta tgtaataaat actatctttt atgctatctg gtaaatactg
    17821 ttgctttaca taatgatttt taaaattatg aggatatttg tatccacaac ccctacctat
    17881 ttctttagaa ccagaatagt gagcatcctt tatactattt ggtatatcct taacaaactc
    17941 tttatccagt tcatccatag ctttcattat tgctatacat gcagaattag actttggaga
    18001 tgtagccaaa agaatagtag cttctgctaa tggtattttc gcttctggaa atccaagttg
    18061 catagctgag tctacacatg cctttacaat tacaatagca tttggataag ctaaacctat
    18121 atcttcacta gctattacta aaagtctcct acatatactt atcaaatccc caccttttat
    18181 aagtcttgct agatagtgta tagatgcctg tgggtcactt cctcttatag atttttgaaa
    18241 tgcacttaaa atatcataat gactatcacc atttttgtca tagtttataa ttttattaaa
    18301 tgtagatgcc cttattacat ctgaatctat ataagttata ttatccttat ttggtttagt
    18361 tgaatagact accacttcca aaatatttaa ggctcttctc atatctccat cagaaagaat
    18421 tgctatatct tcaatagcat cattattaca ctcaatatcc atatagctat cttcatttaa
    18481 tacttcaaca gctcttttca gtcctttttc tatatcaagt ttttctaaag gtttaaattc
    18541 aaatacagta gacctactta aaagagcttt atatacataa tgatatggat tttctgtagt
    18601 gctagcaatc aaagttatac tcccattttc cataaattct aatattgatt gttgctgttt
    18661 tttattaaaa ctttgtattt catctatata taataggact ccatttacat tatttatact
    18721 tccaagctct gatatcacct tttttatatc ttctaaagat gaattagtag catttatttt
    18781 atagaagctt ttattgcttc tttctgctat tatttccgct actgtagttt taccaacacc
    18841 aggaggacca aaaaatatca tatttggtaa aaaattagat tgtaatatct tagacaatat
    18901 ttttccatta cctattatat gactttgacc tattacatca ttcattgttt ttggtcttat
    18961 tttatctgct aaaggcattt tctcactcct ttttaatata cttatcatta ccttaataat
    19021 tcgtctaaaa aaggtatcta tttgaaatag ataccttttc taatctaaac ctataaaata
    19081 tagattattg attgtttttt aattttttta attcatctgt aagtttgtca ttaagtattc
    19141 ttatatgagt acctttcata cctaatgatc ttgattctat cacacctgca ctctcaaatt
    19201 ttctaagtgc atttactatt acagacctag ttataccaac tctatcagct atcttacttg
    19261 ctacaagtaa accttctttt ccatccaatt cagcaaaaat atgttcaact gcttcaagct
    19321 cggagtagga cagagtgcct attgccattt gaactacagc tttctttctc atttcttctt
    19381 ccaattcctc acctattgct cttaatattt caagaccaac aacagttgca ctgtattcag
    19441 ctattactaa atcatcatca ttgaatgaat ttgaatatct tgaaagtacc aatgttccta
    19501 atctttgacc gcttcctaat attggaacta ctgtagtata tttttgtaat cttccatgtt
    19561 cttcaggaaa gatttctaat atcttctcac catttaaatt ttctaatgtt tcatcaattt
    19621 ttaacacatt ttgagtatat tcatctgaaa atttcttttg cttagtatac tcatcttcta
    19681 taactgaact gtcttgaaca tcatttaaat gaagacctag tactttacct tttgcactta
    19741 ctacataaac attagaactt aaaacgtcgc ccaatgctcc ggccagtaaa tcaaaagaga
    19801 cactgcttcc accacttgtt tgtaatgttt tatttatttt ccttgttttt tgtaacactt
    19861 cacttgccat ttaatcatct cctcatgaaa tttaggcctt ttaataacct tttatatttt
    19921 ctaatattat tttcacattt aatgaaaatt tatttttcta ttagttgttt acacttgaaa
    19981 gattatcata gattggaacc tttttcaaga gaattatgtg atttttttca attttcactc
    20041 ttttccgtca ttatgctctt ttgtctcttt attacattct ttattagaac acactgtttt
    20101 tgtttcagat ttagtcactt tttcaaccat atatgaacca cacttctcac aaaactctcc
    20161 tgttggctta ttccaagcta caaagtcaca gtttggataa ttagaacacc cataaaaagc
    20221 tttacctctt ttagattttc taagtataat atctccttct tcacattttg gacatttaac
    20281 accaatttta ttcataattg gtctagttgt tttacaatcg ggatagtttt tacaagccat
    20341 aaactttcca aatctaccat atttgataac catattagaa ccacagttct cgcaaatctc
    20401 atcagtttct tcatccatat ttactttttc tatattttca agagcttctt caatagcctc
    20461 tttaagtggt gcatatgatt ctgatacaat ctttttccaa tctgtattgc cttcttctat
    20521 aacatcaagt ttactttcca tatcagcagt aaaatctaca tctataaatt tatggaaatt
    20581 attttccaaa atatcagtaa ctattattcc aagttctgtt ggacatagac ttgttccttg
    20641 cttttcaaca tactctctat tcagtatagt agctattgtt ggagcatacg tacttggtct
    20701 acctatacct agttcttcta gtgtttttac taaactagct tctgtatatc ttgctggtgg
    20761 ttgtgtaaaa tgttggtctg gcaatatatt ttctatattt aatatatctc ctttttctat
    20821 acttggtaaa attttgtctt ctctttctga aaaattatat accttggtat aaccatcaaa
    20881 tttcattttt gaaccagttg ccttaaatac aatatcgcct attttacatt ctacatttag
    20941 tatatcaaac actgaatctt ccatttgact agctacaaat cttctccaaa ttaaattgta
    21001 taacttgtac tggtctttgc tcaatgaggc ttttatactc tcaggagttc tatcaactga
    21061 ggttggtctt attgcctcat gggcatcttg aaccttttta gtatcctttt tttctttttt
    21121 atcaccaatg tttttatagt agttttctcc taaattgttt acgatataac ccttagcttt
    21181 ttcttttgct tcatcagata ttcttttaga gtcagttctt atatatgata taagaccaac
    21241 agtaccttca ccttctatgt cgataccttc atataattct tgtgctatca tcattgtttt
    21301 tttagtagta aaaaataact tatttgctcc ttcttgttga agcatacttg ttgtaaatgg
    21361 ttttggagct gatttacgtc ttgatttaga ttctatcttc tcaaccttta aatctttacc
    21421 ttccatttct tttagtattt catttacagc ttcttcattt tctaattcaa tcttttcatc
    21481 atttttacca taaaatttca aagttatatc tttgtctttt actgtcttag cctcaacatc
    21541 tattgtccag tattcttttg gaataaatgc ctttatttct ttttctctat cacaaattaa
    21601 ctttgttgta acagattgca ctctacctgc actaagacct tttctaacct tttgccataa
    21661 tataggactt atttgataac ctaaaagtct gtctagcact cttcttgcct gttgtgcatc
    21721 aaccaaattt atatcaatat ttctaggatg tttaattgct tttttaattg catccttagt
    21781 tatctcatta aactctattc tacaatcctc agattcatct aaatttagta tatgagctaa
    21841 atgccatgat atagcttcac cttctctatc agggtcagtt gctagatata cttgtttaga
    21901 ttttttagct tcttttttta attcttttat tacatcgcct tttcctctta tatttatata
    21961 ttgaggttca aaattatttt ctatatctac acctaattta cttttaggta aatctctgac
    22021 atgaccaact gatgctttaa ctgtgtaatg acttttccct aaaaattttt ctatagtttt
    22081 agcttttgca ggcgattcta cgatgactaa tgttttggcc ataaaaccat acacccccac
    22141 tacctaatct taatttatac atttaaactg tacgttttat tattcatttc tactactaac
    22201 tcatttagta ctaattcatt gattattgaa tttacatact ttatttctat accagtataa
    22261 tcacaaatac tatctatatg caagtttcct tctcttttta tagcttcaat tatttgctta
    22321 gacttggcat ttagacttat attatcatat ttttgattta tttttttatc aataatatta
    22381 aatatgttat attcatttaa aatatcatct atattttcaa ttaattttgc accttctttt
    22441 ataattttat gacaacctct actcatttga gaatttatat taccaggtat tgcaaaaaca
    22501 ttttttccat gttcaagagc aaaatctact gtgattagtg caccactttt tattgctgct
    22561 tctacaacaa ctactccatc acttaaacca ctgataattc tatttctatt agaaaaatgg
    22621 tacggggcta ctgtcgagtt aatattatac tctgataata ataatccccc attttctaat
    22681 attttatttg ataaatgtaa attttgtttt ggaagaggat tgtctactcc tgaaccaagt
    22741 actgctatag ttttagattt tccactcata caacctatgt gcgagtatgc atctattcct
    22801 atagctaatc cacttactat attaactcca tattgggata gttgacaact tattgttttt
    22861 gcacaattaa ttccataggc tgtaggtttt cttgaaccta ctatagctat attaaaatta
    22921 ttattaacta agcctatgtc acctttgtag aataataact ttggagcgtt gtatatattc
    22981 tttaaatttt caggatattc tttatcatat ttacaaatat atttaatcgc ttttttgtaa
    23041 agtagttctt ttatattttc taaataagcg tgacctctat attttactat attttttcta
    23101 atattcaagc ttatattttt taaattatat atttcttttt cagaaaaatc aaatatatct
    23161 tcaatattta ctatttcatt ttctattatt tcaattgttt ttgttgttat tccaccaatt
    23221 gattttaacc ataaataagt atctcttttt tccataaaat ccacctcaaa aaactattta
    23281 aaataactat aataagcctt tctaaatgaa aaagcttcta taatacactg tgaatttatc
    23341 aaatctcttt cttctaaatc tgctattgtt cttgccattt ttaaaagttt tgtataactt
    23401 ctactgctta ggttgtattt actaaatatc atctcagccg tttttgaagc ttctttttcc
    23461 agtttacaat atttaaataa attgtaagct ttaatttcac tattattttt tatattatct
    23521 ttcttaaatc tatttatctg tatttttcta gcattttcta ctcttctctt tattttttga
    23581 gagctttctt cttgttttaa agaattaaaa tctgaatatt ttatagaatt aacttctaca
    23641 aaaatatcaa acctatctaa caatggacct gatattttat ttatgtatct atcaatttcg
    23701 ttacttctac atctacactc tgtctctgac atataataac cacatggaca tggattcata
    23761 gctgcaacta acagtactct acaaggatat tttgcactgt actttactct ggatatattt
    23821 acatatccat cttctatagg ttgtcttaaa gtctcaagta tttttctatc aaattcggct
    23881 atctcatcta aaaataagat acctctatgt gctaaagcaa tttctccagg tcttgcatcc
    23941 attcctcctc caattaaaga ttgctttgta gttgtatgat gaggtgctct aaaaggtctt
    24001 ttatcaatta ttcctttagt ttcatttatc atacccaata tactatagac cttacttact
    24061 tctatcattt cttctacact tatatctggt aaaattgtcc ttactctttt tgcaatcata
    24121 gtttttcctg agcctggagg tccaatcata aacatattat gatttccagc agcagcaatt
    24181 tctgcactcc tctttacaaa ataatttcct tttacatctt taaagtcttc atcatattta
    24241 ctttcttcat tattaatctt agtatatttg caatctatat aactattatc tttttctaat
    24301 tcttcgttct cttttcttga cttatcatcc aaaaaagaca ttatccttac tttatcgact
    24361 tttatctctt cgtttaaaaa atcgacacat tcttttaaac ttttaatagg aattatatca
    24421 atttcatcta caaatagact ttcttttatg ttctcaattg gtataaaaat acgttttatg
    24481 ttctgagttt ttgcacccat aattatgggc aatatacctc ttacttttct tattttccca
    24541 tctaatgata attctcctat aaacatactt tctcttatgt aattttcatc tttttttatt
    24601 aactctctta aaaggcctat acttatagat aaatctaaaa aagctccttc tttttttata
    24661 tctgctggtg ataaatttac aactattctc gtgcttggaa atttatatcc actattaaga
    24721 attgctgact ttactctttc tcttgcttct ttaatttctt tgcctggaag accaacaata
    24781 ttaaaactag gtattccatt gcttacatct acttcaacct taactaaaaa gctgtcgatt
    24841 cctactaagt tgcttgaatt aataatactt aacatattta atcctttcca aaaacattat
    24901 cttttttaaa aagcattcat tatgtgattt attctttttt ctaataaata tacctctata
    24961 acatcaaatc ttatgggagt gttatttaag ttatttttta taatataata atttgcaact
    25021 ccaattatct tttttctttt tttgaagctt acagattcac aagggtagcc aaactttatg
    25081 ttagaccttg atttcacctc cacaaatata atttcatctt ccatttttgc tattatatct
    25141 atttccccta tctttaatct gtaatttttt tctagtatct ttgctccttt tgatagcaaa
    25201 taattaactg ctactttttc tccaaaatca cctttttctt tattattcat tattcactcc
    25261 aatacattaa attttcactt ttaaattatg gtcagtatac aattttacta ttcaagtttt
    25321 tggattgatt ttatttccat caatattaat aaatacttct attgacttta ttcttttatg
    25381 atattattct agttttcata ggaaaagttt atttttttgg aggagtgcct ttaatgaaca
    25441 gagaaaaatt agttgctttt atacgatatt tatctttatt tatattagtt gtaagctatt
    25501 tgaaaaatgt tgaaaataca ttgtatccgg tcataactat gataatatta tttctaatta
    25561 taataaataa tcaagttaga tttttttctt tatcaaatga gaataaattt atacttattt
    25621 cttacttttt agaacttata ttaattttta tactttgtaa ttatacaaaa acttttaatt
    25681 cgatttactt tgttccttta atattagata tatcattttt aataaaggaa aaatataagt
    25741 acatattgtt ctcttttgtt ataatatctt ctcttattat tagtttagat aaaaatatat
    25801 atttggcact ggagtcaagc tctatattgc taattataac tgtactttct atatatatag
    25861 aaaatgagaa tttatcaaaa ttatacagtc aaaatcttta tgataagctt agaatttcta
    25921 aagatgaatt aaaaaaagtt aatgctgatt tggaaactta tgcaagttct atagaagaat
    25981 tagcaatttt aaaagaaaga aatcgaatat caagagaaat acatgatagt gtaggacatt
    26041 ctctttctac aacaataata caattaaatg ctatagaaaa actcttaaaa gacaaacctc
    26101 taatttatga cttagtacat gaacttagag aatttgtaac tgaaagtttt caagatgtaa
    26161 gaagggctat atctgagtta aaacctgttg aatatgaaaa ttaccaaagt ttatttaaaa
    26221 tcaaagaatt agttaaaagc tttattaagc ttacaaatat taatgttaaa ttaactattt
    26281 caaaaaatac ttggaactta tccagaaatc aatctatagc tttatataga cttatacagg
    26341 aatccctttc caactcatcg atgcatggaa aggcaactga aatcagaatt tttattacat
    26401 tcaatacttc aaatcttata attactatta gtgataatgg tataggatgt ggcaatataa
    26461 aaaaaggaaa tggacttaat agtatcaatg agagaatata tgaattaaat ggtaaagttg
    26521 aatttgataa ttctaataat ggtttcacaa ttagagcttc ttttcctaaa ttttcagggg
    26581 gtgatttttt tgaataaaat taaagttctt atagtagatg acgaaaaatt aattagaaaa
    26641 ggtcttaaaa ttatattatc atcttataat gatttagaaa ttgtaggaga tgcttctaat
    26701 ggatatgaag ctttagaatt ttgtaaaatg aatgatgtag acatagttct tatggatata
    26761 cgaatgaaag tatgtgatgg ggttctaggt acaaggctta taaaggaata taataattct
    26821 ataacattat taattttaac aacttttaat gatgatgaat atataaaaga tgctatgaag
    26881 tttggtgctt caggatacct tttaaaagat agctctgatg aagtattgca tgaagggatt
    26941 cgttcttcat tttttggcaa tattgtgctt gataaaagtg tagctgaaaa aatcatgacc
    27001 tctgaaaaaa cgattaaaca agagcatctt tatgacatgt acaatttaac agaaaaagaa
    27061 atatctataa ttagactaat tgcaaatgga cttaataata aagaaataag tcaagaacta
    27121 ttcttatctg aaggtacaat aaagaataac ataactaata ttttagctaa actagaactt
    27181 cgtgacagaa ctcaactagc aatctttgct ttcaaaaata aaattgtaat agaataaatc
    27241 taaaaatata aagtgactta agtcactttt tttagtgact tatagtaata gaattataat
    27301 tcacaattct ttattataat attatagctt tttaacttat acaaaattat tttggaggga
    27361 ttactatgga tatagtcaga gtaaataata taacaaaaag atttaatgat aaattagtac
    27421 ttgataacat cagcttttct gttaaaaaag gtgagatatt tggacttatt ggcccaaatg
    27481 gtgcaggtaa atctacactt ataaatataa ttacaaatct tatgttacca aatagtggta
    27541 gtattcaaat caatggttta gatttatcaa aagattatat aaaagcaaag tctataatag
    27601 ggttagttcc acaagaatta gcaattatag aaactcttac cccttttgat aacttagagt
    27661 actttggagc tttctacggt ttaaagggaa aactacttaa agaaagaatc attgaagcat
    27721 tagaagttac aggtcttact gaagtcaaaa agaaaaaggt caaaaaatta tctggtggta
    27781 tgcaaaggag attaaatatt ggaatagcac tcttaaatca tcctaaaata ttaatattgg
    27841 atgaaccaac tgtaggtgta gacccccaat caagaaatca tattttcaat tttataaaag
    27901 atatatctaa aaaacatgaa actactgtaa tatatacttc ccattatatg gaagaagttg
    27961 agcacctttg ttctaaaatt tttattatgg atgaaggtaa agaaattgct tttggaaata
    28021 atgattattt aaaatcactc gtatctacaa atacaaaatt aattatggaa ataaaaaata
    28081 taaatgccca acttatcttt gatttaaaaa atactaaagg tgttatatct gttttagaaa
    28141 ataattcatt attagaattg gatatagata aaaaattaca acttacagat atactctctg
    28201 tcattgacaa aaacaattca aaaataatga aaatttctta tgaagaacct agcctagaag
    28261 acgtattttt aaatctaaca ggaaaaaatt taagggacta atggaggtga ttttatgaaa
    28321 ttatacatga gtgtaaaaac tatgctaaag agtttaaaaa gctcctttat acttaattta
    28381 atatattttt tagctttgcc tctgatttta tcttggtttc ttgggatggt tacagaaagc
    28441 atgtttcaaa accctataaa aacagaatct acccccattg ttatatatga caaagataac
    28501 acaagattat caaatgattt gacaaagtat ttgaaaaatg atttatctta tatattaaca
    28561 gttaaaaaag atgattctaa ggcagaatta aagcttacta tacctaaagg ctatgagagt
    28621 agtttattaa atgaaaaatc aaatactcta aacatagaaa aacttggaac tcgtgatgat
    28681 attgcaatat tgcttcaaga tatattagat acttaccatg aaaaatttta tttaaataat
    28741 tctcagaaaa taagttcaga agatttttct aaattattta ataaaaattc tattgatact
    28801 tctataataa ataacaatgt taaacagagc tcttatgaat actttgcttt agtttcacta
    28861 ggatttcttg taataatttt tataatgaac aatattttgt caaattatat aagtgaatca
    28921 aagggacttt caaaaagact ttattctatg cctataacta gagtacaatt cttaatttat
    28981 gactttgtag gtttatggat ttattcattt atattcttat tattatatgt tttattcttt
    29041 agaatacttg gaataacatt taaaggtaat tttgccatat tgctcctact ttgtgcttta
    29101 tcatcttatt ttatgacttc aatatctacc tttgtaacca gcttttttag taaaaaatac
    29161 ggtacagcaa tagtttatgc attactcttt ttacagacaa tttttggagg tatcttcagt
    29221 atgataagtg atacatttac taagcttaca agtttatctc ctacctattt aataggagaa
    29281 ttgtttagta attatgaaac atttaaaacc atagattcaa taggaaattt aattttcaca
    29341 tgtttaatta tctctacaat attaattgca cttgctattg taaaggaaaa atataaatgg
    29401 agggaggttt aataatgatt agattaacta ttgcaaatat aaaaagatat ctaaaaaatc
    29461 atactctttt aattaatatg gttatgcttc ctattatact aattttttca cttaattttt
    29521 ttatcaacaa ctcgggaaat caatcaatgt acttttctcc agtagcaatt gtatctgact
    29581 cttcaggaaa gtatgaacat aagttaataa atagttctaa attaaaagaa aattcattta
    29641 gattaaatga acaagataag gctatgaatc tattaaaaaa taataaggtt tctgctgtat
    29701 tcgttttaga taaaaatttt tcaaatagta tagataaatt acaacgacct gtagttaaat
    29761 gctttaaaat tgaaaatggt ggtggtagtc tttgggcaga atcacaaata gaatctttta
    29821 ttactaaatc gttaaaattg aaagtggata aaaatataga tgataaattg acaaagacaa
    29881 atataattga taacaaacca gataagaata aaggttcatt tttagtagtc ttcttgatat
    29941 gctattttat gtatattaat gcggcacatc ttgcttctga tttatttaca ttaaaaaaat
    30001 caaatgtgct aaaaagactt atctctacag ataataaaga tataaaaata attttcagta
    30061 tatttttagg actatttttt attcaatcaa ttgtatacac ttttgctcta ttatgttttt
    30121 caattataga agactttaat ttgagtctga atgtattgat gattgtacta gcaaatagtt
    30181 ttgtttccac tggatttgta ttttgggtag ctagagtatt taaaaatgaa agttctataa
    30241 gtcttatatc tacattttat tctttaatag gtctagctat atctatctct agtctaatac
    30301 catcaatgga taaattatcc tttatgacta atctttcaaa gttcacacca ttttattgga
    30361 ctatagatgc tattaaaaac aatggtagta ttttaataaa tataatagct ctaatattaa
    30421 ttggaattat atttgtaact gcaggaagtc ttaaactaag agattttgct aaaaactaat
    30481 aattattaaa tataattagt atctattttt atataattgt aaaagaatat ttcaacatat
    30541 taaattattt tatcttatat ttttctcttt agtttcacac atcaccaagt ctaaactcta
    30601 tattatatat taatattttt gacttgtcaa gttatttatg ttataatatt aatcattaga
    30661 taattaaagc attgtaccta agttgcaata tctaaaattc aatttggagg tataactagc
    30721 atatgtataa aattggtgaa agtgtaatgt atccaaaaga gggagcctgc tctgtaaatg
    30781 atattgtaac aaagaaaata aatcatgaga tgcaaaaata ctatgaatta agtgtcattt
    30841 ttaatagtaa ccttaaaatt tcgattccag ttctaaatgc agatagaatt ggcatacgtc
    30901 cagttatgga tggaaatgat gttgataatt ttatccaatc tattaataaa acagatggtg
    30961 tatggatttt tgatagaaaa gaaagactta aactgtacca agataaattt cattcaggag
    31021 atgtttttga aattgtaaaa ttaatcaaaa tgcttatgat acaagacagt tcaaaacaat
    31081 tgtgtagcac agataaggag tttttaaata aagctcaaaa atttgcttta tcagaattag
    31141 ctgctgctca atgtaaatcc tatacaatgg tattagagga aatgaaaaaa catatattaa
    31201 attcaaagaa tacaaattaa accagttttt taaactggtt ttatttttta tactaatcat
    31261 ccatgctact ttagcttatt ttaaactgcc taatctaata ttaataaagt tatctcaatt
    31321 agatagatgt attttattca aataaaaaaa actaagagta aatcatatta ctgatttact
    31381 cttagctaat aaaatttaat cttcttcaag ttcttttttc tcttgtaata atacacttaa
    31441 ttcatttgct tctaaaactt gtgcctctgc aatatcaagt aactcttgtt gccattccac
    31501 acatttatct ttgtaatcaa aaggtagcgt tctgtcaact atgtacttat caatacagtc
    31561 ctccgcactt ttaattattt cttttctttc atcaataaat ttttctaatt ctactaaggc
    31621 ttcttcataa gcttttctac tcatataaat tccccctttg tacaattatt ctacattaaa
    31681 atgatttttc ctcttttttg tataaaattt tatttgtata taacttttcc atcaatatct
    31741 tttatagttt gacatccagt taatatcata gaactactta gctctgattg aagtttattt
    31801 acataagttt ctacaccatc agttgcacca ccaaaagaag cagtcacaaa aggtcttcct
    31861 attaatactg catctgcacc taaacctatc atttttagta cgtctaaacc agttctcact
    31921 ccaccatctg caagtattgt aactttacct ttaacagcat cagcaatttt tggtaaaact
    31981 tcacatgctc ctggtgtaca gtcaagcact cttcctccat gatttgatac gactattgca
    32041 tccacacctg cttctactgc cattaaagca tcttcaacag tcattatacc tttcaatata
    32101 aatggtagtt tagtagactt tactaactcc tttatttgtt taacattttt aggaagtact
    32161 ggttttccat gtaatgataa agttactaga ccacaggcat ctatatcaac tccaactgca
    32221 aatgcaccag cttcttcagc taatcttatc ttttttataa tattttcatt atcccaaggt
    32281 ttaataaata caattccagc tccattatac tttttgacta catctaaatt ttccattaaa
    32341 aaagcatcta ctgccgtatc accaaccatt gcataaatac cactattaac acatcctgca
    32401 actactggtt ctatgtaatc tctttcatta atttttccac ccatatttaa agtagttcct
    32461 gttactggag ctgcaaatat aggtgcactc attttctttc caaacatctc tatagatgta
    32521 tcaggatttg atacatcatg tattactctc atatttactt ttactttttc taaactcttg
    32581 ctattttcta taaaagaaga accacttcct ttacctccca tgccaggcac ttcacctgca
    32641 caagcaaccc cattacaaac cttacaaact ttacaacttc catttaaatt ttctctagca
    32701 ctttttaata attcattata ttccatcttt aatcccccat taactatagt aatttatatt
    32761 atatacatta tatcatatta tatttacagt atatttttca aaaaactttt tctgtggata
    32821 ggagttatgc catatttttc aatagcttca tagtgttctt tagttccata tcctttgtga
    32881 gatttaaacc catattctgg gtatactcta tcatattggt acattatact atccctagta
    32941 actttagcaa gtatacttgc tgctgctatt gatatagatt ttgaatctcc tttcacaatt
    33001 ggattttgag atatgtcaat acctggtatt gttgctgcat caactaataa ataatccggt
    33061 gcttttttta aacaatttat agcctttttc attgccatat atgtagcatt taatatatta
    33121 aattcatcta tttcttcatt gtttactata cctattccat aatctagtgc ttcttctttt
    33181 attacttcaa aaagttcatc tctttttgcc tcactcagtt tcttagagtc atttacacct
    33241 tctattttgg tatctttttt aaatactaca acagaagcta caacaggtcc agcaagtggt
    33301 cctcttcccg cctcatcaat tcctccaata tataaataac ctttatcata gccttcgttc
    33361 tcaaatatat ttatagtttc caatctttct tcttcttttc taatattatc cagctttttt
    33421 gccagtttta tagctagacc ttgtacagat tttctttcat caactcttaa cagctctata
    33481 tattccatat atttttctac ttctaaagtc tctattattt ctttaatctc cctcacactt
    33541 ttatcctgca taccattccc tcatctttcg tttttaaaaa tttaattttt aaatatatta
    33601 aaatttttta attagagttt aattgcatcc actatagcca cattttaaac atatactaca
    33661 tccacctgta tgtgcaattc cttcacttcc acactcaggg cacacaaatt tttcatctcc
    33721 ttcaaaattt ttatttatta tttctttggc tttttcatct ttattatctt tttctttttt
    33781 attattttta taatattctt ttttactatt ttctttttta tcttctttat tattttcttc
    33841 ctttttttca tttattaaaa ttccactcct tttacatcca tctctaaata ttgttactcc
    33901 tttaagacca gcctcccatg ccttaatata tatattgaaa acatcttcaa ctgtagtttc
    33961 aaaaggtata tttattgtag atgatataga agcatcaata tacttttgcc atactttttg
    34021 catgtttatt ctttcttcat atcctatatt catagcagta acaaaaaaat ctggtaaaca
    34081 ttcttcatct gtaatacctt tcttgtccat atactcttta acaattggag tatatacttt
    34141 ataatacaca tcctcatcat gcaagctttc agtttttctt atatatgaaa gattaaatat
    34201 aggttctatt ccaccactga tacctatcat tgtagatatg gaacctgtag gaggtatggt
    34261 taaaagttgt gaatttctaa gcccatactt tttaaccatt tccttagtgt cttcatttag
    34321 attttctata aaaaacttag atttagaaat attttcatat ttatactcac taaatgttcc
    34381 atattcttta gcaattaatg ctgattgctt cacagcttca tttaacatag tcttaccaat
    34441 taaatcacat agttctaaag attcatcaga accatatctt attcccattt ttataagcat
    34501 atcagctata cccattacac ctaaacctat ctgtctatac ttatgtacac tatctctttg
    34561 ttcttgtaat ggatgcaagt tcaatccctc atctaagaca tcatttaaag ctactacagc
    34621 ttctctaacg caagatttta atttattaat atcaaaagta gcatgttcac caaatggttg
    34681 tattataaac tctgacaagt ttattgagcc aagtagacaa cttcctccac ttggaagtgg
    34741 ttcttctgca caaggattta ctcctgaaaa gcaaaagttc ttatcttcac tcataaaatt
    34801 atatgttttt attttatccc aaaacaatat acctggttct gcataatccc agttattttt
    34861 cacaaattta ttaaataaat cataagcatt tactatctta actatttttt ctccagtagt
    34921 ttcaacttca aaagtacaat tatataactt tttttctctt acagcttgca taaattcatc
    34981 tgttactctt acagaaatat ttgctttagt aaccttctcc aaatctgttt ttatatctat
    35041 aaagtcttct atctctggat gatttacatc catagaaatc ataagagctc ctcttctccc
    35101 tctttgacca attaagccag ttgtcatact gtaaagttcc ataaaagaga ctgctccagt
    35161 cgtatgtttt gcagcattgt taactttcgc tccttttggt cttagctttg aaatatcaat
    35221 tccaactcct ccaccataac taaaagttct agcaagtttt tttgcagtat caaatatatc
    35281 ttctatgcta tcttttggtg gttctattac ataacaatta gaatatgtta ctttttttcc
    35341 ctctttctgt aatcctctat ttgctaaaat tcttccagca aatagaaatt ttttttgtct
    35401 tattagtttt gatattcttg aactattatt tgaaattctc tttatccatt catcaaaact
    35461 ctcaccatta tgtctatact tgttcttcca tattgatttt tgtaattcat caaactccca
    35521 agctttagtc cttatttcag agcgtctttc tctatataat atgtagtgtt ttgctatatc
    35581 ttttctattt gattccataa gtagtacttc aactatatct tgtatttctt ctacggataa
    35641 gcatttttcc atagaattat agtcattagc tatttttctt gatataccat atgccaactc
    35701 tctatctact ccaccttcac tatttatact agctttatag acagcatctt caatcttact
    35761 tttactaaaa agttcttttg taccatctct ttttattatg tatttcattt ttaaacctcc
    35821 aataaattag tattaaatta atacacacat taactataac tctaaacaaa ctttttatat
    35881 atttgtatat tttcatatta attatctaac ataatatata ttatactatt ttatattcaa
    35941 tataacactc cttatagttt tcttaacttg taaaatatct tcc
//
LOCUS       DAYAOO010000037        35018 bp    DNA     linear   BCT 12-OCT-2024
DEFINITION  TPA_asm: Clostridioides difficile isolate ST8-SSI-h139-18
            SAMN40601845-rid21577343.denovo.037, whole genome shotgun sequence.
ACCESSION   DAYAOO010000037 DAYAOO010000000
VERSION     DAYAOO010000037.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN40601845
            Sequence Read Archive: SRR28438827
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 35018)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 35018)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-MAY-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-MAY-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002157583.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002157583.1
            Genome Coverage       :: 163x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/11/2024 16:19:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 4,038
            CDSs (total)                      :: 3,963
            Genes (coding)                    :: 3,930
            CDSs (with protein)               :: 3,930
            Genes (RNA)                       :: 75
            rRNAs                             :: 6, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 60
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 33
            CDSs (without protein)            :: 33
            Pseudo Genes (ambiguous residues) :: 0 of 33
            Pseudo Genes (frameshifted)       :: 7 of 33
            Pseudo Genes (incomplete)         :: 25 of 33
            Pseudo Genes (internal stop)      :: 11 of 33
            Pseudo Genes (multiple problems)  :: 8 of 33
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..35018
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN40601845-rid21577343.denovo.037"
                     /isolate="ST8-SSI-h139-18"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Denmark"
                     /collection_date="2018"
                     /collected_by="Statens Serum Institute"
     gene            319..1512
                     /gene="nifV"
                     /locus_tag="ACGI5H_002030"
     CDS             319..1512
                     /gene="nifV"
                     /locus_tag="ACGI5H_002030"
                     /EC_number="2.3.3.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418528.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004410 - homocitrate synthase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="homocitrate synthase"
                     /protein_id="HFG9697733.1"
                     /translation="MCVISKDRAKEIKIVDTTLRDGEQTAGVVFANREKIMIAEMLSD
                     LGVDQIEVGIPTMGGDEKNVIKHICSRNLKSDIMAWNRAVIKDVEESISCGVDAVAIS
                     ISVSDIHIENKLRTSRGWVLENMAKTVEFAKKNGLYVSVNGEDASRADIDFLTEFINV
                     GKQAGADRFRYCDTVGVMNPFSIKNAIETLYERTNFDIEMHTHNDFGMATANALAGIA
                     AGANYVGVTVNGLGERAGNAALEEVLMALKCVYKCDLNNIDTRKFRGICEYVAQASGR
                     ILPTWKPVVGDNMFIHESGIHADGALKDPHNYEPFDPSEVNLERKIVIGKHSGRAAVV
                     NKLSEYEMYISPENATKLLNAIRATSIRLKRSLMDKEILQLYCDILAHEKGTTEEEAV
                     RGSYI"
     gene            1537..3462
                     /locus_tag="ACGI5H_002031"
     CDS             1537..3462
                     /locus_tag="ACGI5H_002031"
                     /EC_number="4.2.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895860.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aconitate hydratase"
                     /protein_id="HFG9697734.1"
                     /translation="MGDNIVYKIIKKHIVDGEAVAGSSIGIKIDQTLTQDSTGTMTYL
                     QLEAMGIDKVKTKRSVAFVDHNMLQQGFENADDHKYIQTVADKYGVYFSKPGNGICHQ
                     VFLERFSTPGDTLLGSDSHTPTAGGVGMMAIGAGGLDVALAMAGGAYYIKAPKVCKVN
                     LVGKLNNMVSSKDIILEVLRKQTVKGGVGKVYEYGGEGVKSLSVPQRATITNMGAELG
                     ATTSIFPSDEKTLEFFKSQGREDAWVELKPDADAVYDEEITINLDELKPLAAKPHSPD
                     NVDEVENIGKIKIDQVAIGSCTNSSYEDLMKVAQILKGNKVHKDVSLVIAPGSRQVME
                     MIARNGALADIISAGARILENSCGPCIGMGQSPGTDSVSLRTFNRNFYGRSGTLSAQV
                     YLVSPEVAAVSAIKGVLTDPREFDIKFTNLDVNEFLIDDSMIIKPADVGSDVEVVRGP
                     NIKPFPLNTELSQSIGGKVILKTEDNITTDHIMPSNAKLLPFRSNIPYLANYCFNTVD
                     TEFPQRAKDNNGGFIVGGDNYGQGSSREHAALAPLYLGVKGVIVKSFARIHKANLINS
                     GIIPMEFCDEKDYENISLLDNLEIPNILDNLGSGILEVKNTTKGTSFKVKVELSAKEV
                     DVLKAGGKLNYTKNQAN"
     gene            3484..4479
                     /locus_tag="ACGI5H_002032"
     CDS             3484..4479
                     /locus_tag="ACGI5H_002032"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902188.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="isocitrate/isopropylmalate dehydrogenase family
                     protein"
                     /protein_id="HFG9697735.1"
                     /translation="MYKVTLIPGDGIGPEVAKAMKKVVEATGVEIEWEEVNAGEAVIE
                     EYGTPLPEYIIDSIKKNKIAIKGPITTPVGKGFRSVNVTLRQALDLYVNLRPIKSFKG
                     IKSRYEDVDLVVVRENTEDLYAGIEHKIGDYAAESIKIITRSASERIVDFACNYVKDN
                     KRKKVTAIHKANIMKMSDGLFLDVFREVASKHGVEYDDLIVDAAAMNLVLNPENYDVM
                     VMPNLYGDILSDLGAGLVGGLGIIPSANIGKDCAIFEAVHGSAPQIAGQNKANPTALI
                     QSSVMMLRYLGEYENAQKIETALEKVFLEGSKLTVDLGGSASTTEFADEVCKYIV"
     gene            4804..5277
                     /locus_tag="ACGI5H_002033"
     CDS             4804..5277
                     /locus_tag="ACGI5H_002033"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012816057.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family winged helix-turn-helix
                     transcriptional regulator"
                     /protein_id="HFG9697736.1"
                     /translation="MVVSVEVCLIKTLDSNILREVGTLSRAVNSINDIKYKELKLQKG
                     QFTFLTRICENPGINLVELSNMLKVDKATTTKAIQKLIKAGYVDKKQDKFDKRGYNLT
                     PTDKSLEVYELIIEEENRSIEICFDNFTDEEKQVVTKLLEKMSKNVENEWFKVKR"
     gene            5311..5805
                     /locus_tag="ACGI5H_002034"
     CDS             5311..5805
                     /locus_tag="ACGI5H_002034"
                     /EC_number="2.3.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004453626.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:0016746 - acyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HFG9697737.1"
                     /translation="MIRKANMNDLESIMKIIKSTVEEMKTYNNTQWDENYPLEKDFVS
                     DIKKQDLYIYEVDGEVAGFICLNYEEPEEYLGLNWSSNKKAMVIHRMAVNPNFRKTGI
                     ASKLVDFAEKLAVENNVSYLKSDTYSINSKMNLLLTKCGFIKIGEMSFLGKEKSFYCY
                     DKIL"
     gene            5902..6423
                     /locus_tag="ACGI5H_002035"
     CDS             5902..6423
                     /locus_tag="ACGI5H_002035"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895862.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nitroreductase family protein"
                     /protein_id="HFG9697738.1"
                     /translation="MIGFLKKRRSIRKYKDVEVEKEKLDKILKAALLAPSSKGLRTWE
                     FIVVDDKEKLINLSQCRTKGGGFFLKNAPLAIVIIADKEKNDVWIEDASIAASYIQLQ
                     AHELGLGSCWIQVRNRMHDDNIEADKYIREELKVPSKYSVECIISIGYPDEEKKAYGD
                     SDLDYKKVHFNNF"
     gene            6612..6923
                     /locus_tag="ACGI5H_002036"
     CDS             6612..6923
                     /locus_tag="ACGI5H_002036"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004453624.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein"
                     /protein_id="HFG9697739.1"
                     /translation="MGIFKTKMDEDWKVNYIKEFNEMRDSYESKLQKKQFEVDSLKSE
                     LDRLRSYKNSLKPKEKQITDDDINNIKSLRRDGLSYKEISNQTSWSKATVSRVLNGLY
                     D"
     gene            6951..7637
                     /locus_tag="ACGI5H_002037"
     CDS             6951..7637
                     /locus_tag="ACGI5H_002037"
                     /EC_number="3.4.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895864.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0070007 - glutamic-type endopeptidase
                     activity [Evidence IEA];
                     GO_process: GO:0071586 - CAAX-box protein processing
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane glutamic
                     endopeptidase"
                     /protein_id="HFG9697740.1"
                     /translation="MKYSYKKCIIDSILLMFIVQILRMILNYVLLSQFEFTLENFNII
                     NLISFTLVGLSLILFLKDNSLYNKVRNRKITEAFEENKNNILIEKCKLILFVVVLSLA
                     IIVTYCTKGYVLFNVTMMTLSVLIVPIFEELFFREYIWNYLSNFIKSKSKIICITSIL
                     SGIYNIGYIDVIRNYVILYNNSSYTFEVIISKIMIGTVFGIVLGLVKYRFRDVGFCIL
                     LRSLFAIFIR"
     gene            7869..8753
                     /locus_tag="ACGI5H_002038"
     CDS             7869..8753
                     /locus_tag="ACGI5H_002038"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888650.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003824 - catalytic activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="fumarylacetoacetate hydrolase family protein"
                     /protein_id="HFG9697741.1"
                     /translation="MKFVTFCSSNEEKIGVFNSETNSIYEINSLGLSKLYTDMNDFIE
                     NVSTGDLEKIKNNSFENAKCYKLEEVKLCSPIVRPKKDIICLGLNYKDHVNEIPDGVI
                     KNVVMPDYPIYFSKRADKIIGVDDKISLHGDLVEKLDYESELAVIIGKEGINISKEDA
                     YEYIFGYTIVNDISERALQDKHVQWFRGKSLDTHTSMGPCIVHKEEFEHPLKLDISSV
                     VNGEVRQDSNTEYFIFDIPTIINDLSRGMTLKPGDIISTGTPAGVAMGMNPQVYLKHG
                     DIVECKVEGIGVLKNIVD"
     gene            8852..10027
                     /locus_tag="ACGI5H_002039"
     CDS             8852..10027
                     /locus_tag="ACGI5H_002039"
                     /EC_number="2.1.2.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860970.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003937 - IMP cyclohydrolase activity
                     [Evidence IEA];
                     GO_function: GO:0004643 -
                     phosphoribosylaminoimidazolecarboxamide formyltransferase
                     activity [Evidence IEA];
                     GO_process: GO:0006164 - purine nucleotide biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylaminoimidazolecarboxamide
                     formyltransferase"
                     /protein_id="HFG9697742.1"
                     /translation="MARELELKYGCNPNQKPSKIYMKNGELPIEVLNGKPGYINFLDA
                     FNSWQLVKELKEATGLPAATSFKHVSPAGAAVGVPLSDTLKQIYFVDDLELSPLACAY
                     AMARGADRMSSYGDFIALSDVCDKETATIIAREVSDGIIAPGYTDEALEILKGKRKGN
                     YNIVKIDENYTPEPIETKDVYGITFEQGRNEILINEDLLKDIPTDNKIFTDSAKRDLI
                     IALITLKYTQSNSVCYAKDGQVIGVGAGQQSRIHCTRLAGNKADTWYLRQHPKVLNLK
                     FKKDIGRPDRDNTIDVYLSDDYMDVLADGIWQNFFEEKPEPLTGEGKRAWLKTLTGVA
                     LGSDAFFPFGDNIERAKRSGVSFIAQPGGSIRDDNVILTCNKYNIVMAFTKNRLFHH"
     gene            10155..11009
                     /locus_tag="ACGI5H_002040"
     CDS             10155..11009
                     /locus_tag="ACGI5H_002040"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423488.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9697743.1"
                     /translation="MALNIRNYSLLCNQGTAKFNEDVVGINPFGAWVLDGATGLNGKN
                     LVSTESDARWYVQWWNRYLYKNINKEESLKSIINTGIIEVKKEYELRLNGFKVEKLDL
                     PSSSIVVVKFHENKVEYFLLGDCALFIKNGDSKVIKDRSICKFDNTVFDEMSKLSNLE
                     EMAFDEIRTSVMDTIVSNRLKKNTKEGYWILDFDEEAVENSIYGYIEIKKDFQLMLTS
                     DGFTSACDRYNLIKEEELIRIAEKFGIGYIHNKVRDFEDNDYKAVKVPRFKVKDDSSC
                     LYLDIYND"
     gene            11053..12288
                     /locus_tag="ACGI5H_002041"
     CDS             11053..12288
                     /locus_tag="ACGI5H_002041"
                     /EC_number="2.4.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888653.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016757 - glycosyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 4 protein"
                     /protein_id="HFG9697744.1"
                     /translation="MKILHIITQKPNSTGSGIYLSGMIKGFEKIGHKQAVIAGIDVND
                     DVNCFPSEVSFYPVKYNCGELNFPVVGMSDSMPYESTRYKDLNIDMINRLKYQFKVNI
                     DKAMNDFKPELIICHHLYLLTAFVREMVKDIKVMSICHGTCLRQLNTIDLEKEYIIAN
                     IRKLDLIFALHENQKYDIIKTFGVSESKVVVIGSGYNDDIFYNKNYKIKDDKIKIVFA
                     GKICKSKGLIPFIKAISKLKYSKDLIEVNFAGTGSDIESYNEIVKLASKSPFKMNFLG
                     KLEQRDLAELFNRSQIFVLPSFYEGLPVVVLEALSCGTDVITTDILGVKEWIGSEINN
                     SGKIEYVSLPFMEKEGIPKDEELYDFENNLYNAIDSKIQSLLNNSNKKTSVDMSKKTW
                     DGLAYRINEVILMDELCLV"
     gene            12389..13330
                     /locus_tag="ACGI5H_002042"
     CDS             12389..13330
                     /locus_tag="ACGI5H_002042"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454223.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall-binding protein Cwp25"
                     /protein_id="HFG9697745.1"
                     /translation="MRISKKVLALGISALLLSVSFPTSINALDKIENIQGVDKYETAG
                     LISDKQDFTTAVLINADSTMVDGIAASGLAGVNNAAILLTNKDDIPEATLQRLNRVTK
                     IYVIGGENSISKDVEKMLLMRRMQVIRIDGVDRVDTSYKIAGEIEKIKNSDKMFLVNG
                     FKDEADAVSVASVAYRDGAPIILTKDIPSAEEDTDLDPWFGVSPVPVYAIGGESTLSD
                     YIVSRYRATRIGGVDRYQTNKNVIEKFYNGAKEFYITSGDDLVYALVASPLAKNAPVV
                     LVSNKSDKSILSGASKVTAIGISDKSIIEQCLDAVKK"
     gene            complement(13549..13902)
                     /locus_tag="ACGI5H_002043"
     CDS             complement(13549..13902)
                     /locus_tag="ACGI5H_002043"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418555.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004518 - nuclease activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GIY-YIG nuclease family protein"
                     /protein_id="HFG9697746.1"
                     /translation="MDRKRELKQLYKEMKFDTGVFIIKNDITKKIYLGKSNDIKSKFN
                     SLKFQLGAGSCMIKELNNEWKKYGEKAFTFEVLELIKHDDNKTEKDYLEELDILEMVW
                     LEKLKEDNTYEIYSI"
     gene            14198..15109
                     /locus_tag="ACGI5H_002044"
     CDS             14198..15109
                     /locus_tag="ACGI5H_002044"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004453609.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CGNR zinc finger domain-containing protein"
                     /protein_id="HFG9697747.1"
                     /translation="MNKKIELIGNFASDWIRYSDYEYKITEEDELYIVPTEDAVFTMY
                     NPFDVADDIIVDIIRIGQEALQDISKETKEMKLKKEVLEFVKKYGLLGLIYSSVYNRD
                     IVGEERVLMIEKNYITKENILSTDEYVNMFIPFASDEDVYFKKYRRGIDVSKREESPK
                     FFGKRPLILDLVFSKFYTEQLDWIVSFAKDMCKHFNQICVYKNTSNLLTESVTIMSGG
                     FNPQKIGFSISQLDKPIIAWEFDSLKTAIETIYAFAITSEPSSLNKCKYCGKIYIPTN
                     SKSQYCSPSCRNCSNVKKSRSRAKKDK"
     gene            15369..15803
                     /locus_tag="ACGI5H_002045"
     CDS             15369..15803
                     /locus_tag="ACGI5H_002045"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902196.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF6323 family protein"
                     /protein_id="HFG9697748.1"
                     /translation="MISPIILSSINQNLKEIERNELLETNIESGDYGLALSESDVKDI
                     INSRDNTLKGYGRIELDIKVTKQLIENIYTSQYTNVDNYLEAINDMQEIFYYLKNETD
                     DKICDDEIIEILGEFYEKFSGNMDNVRGEADEFAKKFKFGEV"
     gene            15826..17361
                     /locus_tag="ACGI5H_002046"
     CDS             15826..17361
                     /locus_tag="ACGI5H_002046"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728720.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF6179 domain-containing protein"
                     /protein_id="HFG9697749.1"
                     /translation="MLNNLSNININENNLIKNQYSISLLKECLNCKVIDEREVYNIQQ
                     EVSLILMDLIKKYTNGQSTSVKTEVAEKLLISIWYAIDAYINKLGDIEKRVVELTAKN
                     VKKVYLGGIEILEEELVRLKDFYKLMMSRKLDTNSIAYNDTLMELSSFFKSYIVKFEA
                     QDVPVSIDYPLALDDMDVKGIYYVKNYIESIDIENRFCNLFKKKDREKLFYDYGMTYK
                     IDCDVILVNLFELIMNNCIFSTILGNEVTNLEISKYEYEFLEKQFKNMYNNITEDKVI
                     DSEESNIIELIEVDDSFNTEVDSNLDYNDFEEINREIRINKKITLLLMEAIEVLIKRL
                     SIEDEDVIRYIKKYEKIFIESVLSSIKSNTFKSMVTVSKNKKEHLEDYIVDDESKLDD
                     ESFREIFNEILDSTSIIEKIRIIKENINAKKDFIDILESECLFGEEYLMLFASLSELE
                     LAILGSVVFYEDIRMREINILEFMLNEKTETTLWKIEYIKFMKRQSEDKIYSIEEHMN
                     KIN"
     gene            17445..18812
                     /locus_tag="ACGI5H_002047"
     CDS             17445..18812
                     /locus_tag="ACGI5H_002047"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888658.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M20 family metallopeptidase"
                     /protein_id="HFG9697750.1"
                     /translation="MKEYIINNVEEIREELIDLSKKIWENPELAFEEKYASSIQKEYL
                     KSKGFKIEEVENLPTGFIASFGEGKPVIGILGEYDALPELSQCVSAERKPLVEGKAGH
                     GCGHNLLGVAGVGAVVSIKKLIEENKFNGTIKYFGCPAEEEGGGKTVMCINGCFDDVD
                     CAFTWHPFDINAPWRGGSLANLSVKFKFKGITAHAAQAPHNGRSALDAVEIMNVGANY
                     LREHVIDSIRMHYVITNGGGRPNVVPGFAESWYFIRGKKAKDAEHVLDRLIKVAQGAA
                     MMTETEMEYKVTDGIYDYIPNQCLTDLVYDNMVFVGCPKNTPEEEEFAKKLCDTLTRE
                     ERLGVATSLQNDKSIVESYIHKEIVDGDKDKGLAGSTDVGDVSYVIPVAQFAMAAWPV
                     GIASHTWQSCSSAGSNIGFSAMINSAKVLACSAYDVFMDTKIIDEAKIEFDKSLDGQK
                     FKPLV"
     gene            18847..19071
                     /locus_tag="ACGI5H_002048"
     CDS             18847..19071
                     /locus_tag="ACGI5H_002048"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015759013.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NifU family protein"
                     /protein_id="HFG9697751.1"
                     /translation="MREKVEKVLEEKIKPVLQRDGGDVELIDVNENGVVLVRLQGACS
                     GCPGVTMTIKAIIENVLVSEVPGVTQVLGV"
     gene            complement(19521..19919)
                     /locus_tag="ACGI5H_002049"
     CDS             complement(19521..19919)
                     /locus_tag="ACGI5H_002049"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004453603.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HsmA family protein"
                     /protein_id="HFG9697752.1"
                     /translation="MNYKLILAIVFITSALIFYTIGVFGERKAKILKKKHVIIFWLGF
                     IFDTLGTFTMSNIANSHTFEVKSALSQNLHSITGLLAIVLMLFHASWATFVLYKDDEE
                     KKKFFHKFSIVVWTIWLVPYFIGMFIGMAG"
     gene            complement(19922..20365)
                     /locus_tag="ACGI5H_002050"
     CDS             complement(19922..20365)
                     /locus_tag="ACGI5H_002050"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012816060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family winged helix-turn-helix
                     transcriptional regulator"
                     /protein_id="HFG9697753.1"
                     /translation="MILLKSNYDCFRIAMLLKELYSKTMYTVEENFKENGLTHQQIIV
                     IKLIAHNQELTISQLCDEMSLAKGTVSGIISRLEQIGYIEKFKKSNDKRNTYVKFTTT
                     GFEFATNFKIKMQESFDDIFKNCDENELSDLVKNLRNILAKVKER"
     gene            20683..21669
                     /locus_tag="ACGI5H_002051"
     CDS             20683..21669
                     /locus_tag="ACGI5H_002051"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888668.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HFG9697754.1"
                     /translation="MLKDILKKLLQFILVMFLLSFIVFYMARLAPGDPLISYYGDGVE
                     RMSTQEKENAMKKLGLDEPIYSQYIKWISNASKGEFGISFKYKQNVTSVINDVYINTI
                     ILGGSGYILTFVLALLLGIFCTLHEDKLIDRIICKLGTITNCIPSFWVALVLILIFSI
                     NLSILPSSGAYSMGEESSILSRISHLILPLTVLILSHLWYYTYMIRNKLLEEIREDYV
                     LLCKAKGLNNRTIVFKHCLRNIMPSYISIMAISIPHILGGTYVVEKVFSYPGLGTLCF
                     ESAKYHDYNMLLVLCLITGALVVFGNMLAQIINNKIDPRMKYDRGDTNEATI"
     gene            21653..22564
                     /locus_tag="ACGI5H_002052"
     CDS             21653..22564
                     /locus_tag="ACGI5H_002052"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888669.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HFG9697755.1"
                     /translation="MKPQYSDFEIVGENYILVAEDEHIETKKTLSKKIKELPYISIII
                     LSIIVIGSVFSSFIMTHEPTYMDLASSNLAPNKTFLFGTDSMGRDIYSMIWYGGKISL
                     FIGLFSTVISTVIGIVYGSISGSASELVDDAMMRFTEIILSIPSILIIIFVQAILGNS
                     NPVSMSIVIGITSWMNISKIVRTEVRQIKNSEYILAAKSMGGGFFYVLKQHLLPNFVA
                     SIMFMVVTNIGAAIGTESTLSFLGIGLPIEIVSWGSMLSLSEEALLSNRWWIILIPGI
                     FLVTTLVCITNIGNYIRKNNNKKSSNL"
     gene            22677..24245
                     /locus_tag="ACGI5H_002053"
     CDS             22677..24245
                     /locus_tag="ACGI5H_002053"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004453597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HFG9697756.1"
                     /translation="MKLKKLKVLSLVMILSLMAGCSSGGDKDKKADTPKDGKVLVYGS
                     NDYTSINPALYEHGEINSLIFNGLTAHDENNKVVPCLAKDWKFDEATNTYTFNLRDDV
                     KWHDGEKFTANDVKFTIETIMNPDNASEIASNYEDITKIDVVNDNTIKITLKAPNTAM
                     LDYLTVGVLPKHALEGKDIATDEFNQKPIGTGPFKLEKWDKGQSITLVKNSDYFVKEP
                     GLDKVVFKIVPDDKAKAMQLKSGELDLAQITPKDMSNFEKDEKNFKVNIMKTADYRGI
                     LYNFNSKFFKDKKAKGLPNALSYAIDRKAIVDSVLLGHGVPAYSPLQMGPYNNPDIEK
                     FEYNPEKAKQEIEKLGWKLGSDGIYEKEGTKLAFEITAGESDQVRVDMAKICAQQLKE
                     IGVDAKAVVVTETDWANQDAHLIGWGSPFDPDDHTYKVFGTDKGANYSAYSNPTIDKI
                     LQKARETEDKDEKLKLYKQFQVEMTKDMPYTFIAYIDAIYVGKPNIKGLTPDTVLGHH
                     GVGIFWNIADWTIE"
     gene            24320..25345
                     /locus_tag="ACGI5H_002054"
     CDS             24320..25345
                     /locus_tag="ACGI5H_002054"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418581.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HFG9697757.1"
                     /translation="MEHLLEVNNLSVSFKVEEGEVQAVRNVSFNLKKGETLAIVGESG
                     CGKSVLCKSLMRILPYNGYIKNGEVLLKSSDLVKKSEKEMEDIRGKNISMIFQDPMTS
                     LNPTISIGKQIAEAVIIHQGISKSEAKKRAIELIELVGIDNPEKRFKQFPHHFSGGMR
                     QRIVIAIALACNPDVLIADEPTTALDVTIQAQIIDLIKDLQHKIGLSIIFITHDLGVV
                     ATIADRIAVMYAGKIVEIGTVEDIFYDPRHPYTWGLLGSLPTLDSQDDYLYNIPGMPP
                     NLLNPPKGDAFAIRNKNALKIDYEKEPPMFKINDTHSAATWLLHPDAPEVDVPVRVNC
                     GRVISNE"
     gene            25338..26282
                     /locus_tag="ACGI5H_002055"
     CDS             25338..26282
                     /locus_tag="ACGI5H_002055"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004453594.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HFG9697758.1"
                     /translation="MNREKILEIKNLKQYFHLDKSTTVKAVDDISFDIYKGEIFGLVG
                     ESGSGKSTTGKTIIRLHESTGGEVIYKGNCISDKKTYKFIKKDVNKSMQIIFQDSTSS
                     LNPRMTIADIISEPLKIQGICKNKTDRMNKVYEMLKLVGLDRSYANKYPSDFSGGQRQ
                     RIGIARALSVDPEFIIADEPIASLDVSIQAQIVNLFKKLQQEKNLTCLFIAHDLSMVR
                     HISDRIGVMYNGKLVELADSNELYNNPIHPYTKSLLSAIPVPDPRYAKSRNRIEYNSN
                     GYDCSNEKSLSWIDVSDGHFVYSSKSEINKYQQNLKVV"
     gene            26641..29298
                     /locus_tag="ACGI5H_002056"
     CDS             26641..29298
                     /locus_tag="ACGI5H_002056"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418584.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0008134 - transcription factor binding
                     [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sigma 54-interacting transcriptional regulator"
                     /protein_id="HFG9697759.1"
                     /translation="MIYKKDKVMKVLESSYRENEKGITANQLSEKTGIARNNISTYLN
                     QLFNEGMVTKIKGRPVYYIPANLNLNKNELLDTQSELLGIKKGTKVENKIKKDSFETL
                     IGKEHSLRPIIEKCKVAMLYPTNGLHTIIYGETGVGKSMIARYMYDYSIDSGIRKNKA
                     PFVTFNCADYANNAQLLMGHIFGVEQGAYTGAESSRKGLLEIANGGILFLDEIHRLPA
                     EGQEMLFTFIDKGTFKRLGDATKERESKVLIICATTENPTSTLLDTFNRRIPMKIEIP
                     SLRDRTMIERMELVKNFFKEESKSISISIKVHKEIIKSLLLYDCKNNVGQLQNDIKLA
                     VANGYLRYKRDNKEPVYIEKKYFDKSINEVSDDYREKSIKADEVITHGIEYFVFTSLG
                     EEEVINYNDINIINAVNTNLNKSVEMNIADASLFNNVKFKSMCESIRQIIKEDEEIDI
                     SESIFKSMAIYIKSVLDKSSSTNNIDLNQIRRNNRSEFKTALKIVGIIENEFDLFLSI
                     ETVAYITLFIVQAKQDEQNKIVNNINIIVAMHGETTASSMVKAVGDIIGKCSAISFDM
                     KLDKSYDEVIVDFKNLINNIDNKDVLLFTDMGSLNSFDEIIKKEKKCGVRVIPMVTTL
                     TVLEAVQKANMGLPLNDVYNSITNTRKYYFGTNEIQNKENLSKTIIIASHVSEGVDNK
                     TRKILEEKMSRYLDGIDIISVPYKTEKDLSLNITKLKESSNIVAVINEQRINIRGIDY
                     ISKKDIDKDENINKLKNIIKISIGYDDVVEGLKTSLKSSNYNRIFKDIKYVSDELFLV
                     FNIEKKYDKVIGLMMHLAFMVDGLIGNTREIEKLDKEKTLDYHKSLSKIKDIVSQLDK
                     KYNIEINEKECYQILLILEYAEIIEKDYQ"
     gene            29513..30142
                     /locus_tag="ACGI5H_002057"
     CDS             29513..30142
                     /locus_tag="ACGI5H_002057"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004453592.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9697760.1"
                     /translation="MQDKILRDKKANDPWARMTTRNGFSADEIISSFQKAIRRNMVEE
                     ACEFAYELYISSPELEDKLWRRILTISVEDIGMGDPSAVIIINNLNQVRKEYSYADGD
                     RPLFFIHAIRYLCACEKDRSSDLLKNIIIKGFAMGKVPEVMDVALDKHTYRGLEMGRD
                     SFHFLNEASIVIPEKEVDNDYKERYLKILEKYKQEEVIDTAFKFNHWQY"
     gene            30277..30603
                     /locus_tag="ACGI5H_002058"
     CDS             30277..30603
                     /locus_tag="ACGI5H_002058"
                     /EC_number="2.7.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004453591.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HFG9697761.1"
                     /translation="MNILLVCANGASTGVLVEKMKSFCSEHEKLKTKTINIEATSFEN
                     LKSYIEANDTDVVLVAPQIRFKEDDVVEACKNYKIAVGLIDTKHYGRMDAPSVMKSAI
                     ELYKNR"
     gene            30619..31908
                     /locus_tag="ACGI5H_002059"
     CDS             30619..31908
                     /locus_tag="ACGI5H_002059"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892810.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HFG9697762.1"
                     /translation="MEALQNNLRRFLLPIAQKIEKQRHLQAIKEGMISITPIIIVGSL
                     SMLFMALNNMLPEGSAKTLLSENMDTLLIPNKFTMSLLSIYSAFFIAQALAKKYNLNH
                     VEIGMTAVVAQLVVCGQVVDGVLDTSYLDAQGLFVSILVALLVVDITKFMNDKNLVIR
                     FPKEVPSVVNKSFRNLTPMIVCIMLFTAIAAITKNVSGQPLPAIIMNFLAPAISSVDN
                     VFAVTIILFITQLLWFFGLHGAAITSSIWMPIAATYMAENATLIAAGGDPKYVFTIGF
                     YYGFLQVTGSGITLGLVYLMSRSKCKSFNSMGKVVILPSLFGINEPVIFGTPIVMNPY
                     MFVPFVFGPVLVGALNFMALKVGLVGLPIAEPPGFLPPGVAAFLMTLDWKAIVLVFAS
                     IILMTLIYYPFFKIMEKEELNKNAELATTLDDDSFDF"
     gene            31932..32261
                     /locus_tag="ACGI5H_002060"
     CDS             31932..32261
                     /locus_tag="ACGI5H_002060"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004453589.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose/cellobiose transporter subunit IIA"
                     /protein_id="HFG9697763.1"
                     /translation="MVPEMEEKVFSIISEAGDAKSDVMMSLKEIKKGDYNKAKHLLNS
                     ASEKIQTASKHHLELLSNAMNSEDSGTDFLVVHSEDHYSNALFAHSLVSELVDIFEMM
                     DPRINKN"
     gene            32409..33737
                     /locus_tag="ACGI5H_002061"
     CDS             32409..33737
                     /locus_tag="ACGI5H_002061"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728718.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phospho-alpha-glucosidase"
                     /protein_id="HFG9697764.1"
                     /translation="MEKFSVVIAGGGSTYTPEIILMLLDNLDRLPLRAIKLYDNDEER
                     QNKVAKACEILIKEKDPNIEYLATTCPKEAYTDVDFCLAHIRVGKLEMRELDEKIPLK
                     HGVVGQETCGPGGIAYGMRSIEGVLENIDYMEKYSPNCWMLNYSNPASIIAEAVRRLR
                     PNSRVINICDMPIGMEHNIARIAGLKSRKHMDIRYFGLNHFGWYTSIKDKKGNELLPK
                     LVEHIKEYGFINGEEGMKNDKKDSWFETNLFTKEIVKTDLTTIPSSYLKYYLFPDYVV
                     NHSDVNYTRANEVIDGREKEVFGSCALIEKQGHSKGSGLKIGIHAEFIVDLATALAFN
                     TQERMLLIVQNNGAIENIQDDAMVEIPCIVGKDGYEPLSIGKIPTFQKGLIEQQLAVE
                     KLVVDAWIEKSYNKLWQALMLSKTVPSATVAKELLDDLIEANKNYWPKLN"
     gene            34060..34914
                     /locus_tag="ACGI5H_002062"
     CDS             34060..34914
                     /locus_tag="ACGI5H_002062"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888678.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein-ADP-ribose hydrolase"
                     /protein_id="HFG9697765.1"
                     /translation="MKWRDYADDVNLFEDFDKTIKPLTDEQRRKNINTLIAYFSKEVP
                     SKIYNLSNDEIKPRDILRGLLNVYPPKEIAPEILNMLHNLLLIECEERELVDVNDIEE
                     IEEGIAIWRGNITNLRADAIVNAANNKLLGCLQPLHLCVDNEIHSCAGPRLREDCDKI
                     IKKQGHLEYTGDAKITRGYCLPAKFVVHTVGPIVSGGQPSKEQEKQLLHCYKSCLNTI
                     KEIDEIKNIVFCGISTGVFGYPKKEAANLAVSRVRLWLKENPEKNLKVVFNVFTEEEE
                     EKYRRIFK"
BASE COUNT        14017 a         3556 c         6361 g        11084 t
ORIGIN      
        1 aattaaattt tagtaggaat tttataggtt tatttttaaa ggttttttga aaataaatct
       61 atttaaaaat taaattaaaa tgcaagaaaa acataataac tttcattttt aagaagtttt
      121 cacaaaaaag aaaaaatata gtgcaataaa tgatacaaag taatataata gattacaaga
      181 tatgaaaagc taaaaaaata aattgcaaat gaaattaaaa tgaataaaaa ataaaaaaat
      241 aatcataagt tagaagtatc aatgaaaaat aagacttaat gtttttaaaa ttaaaagtat
      301 actaaggggg gcattaatat gtgcgttata tcaaaagata gagcaaagga aataaaaata
      361 gtagatacta ctttaagaga tggagagcaa acagctgggg ttgtatttgc aaatagagaa
      421 aaaataatga ttgctgaaat gttaagtgac ctaggtgttg accaaattga agttggtata
      481 cctactatgg gtggagatga aaaaaatgta ataaagcaca tatgtagtag aaatttaaaa
      541 tcagatataa tggcttggaa tagagcagta ataaaagatg ttgaagaatc tatttcttgt
      601 ggtgttgatg cagtagctat atcaatatca gtatctgaca ttcatataga aaataaattg
      661 agaacttcta gaggctgggt tttagaaaat atggctaaaa cagttgaatt tgcaaagaaa
      721 aatggattat atgtttcagt aaatggagaa gatgcttcaa gagcagatat agacttctta
      781 actgaattta taaatgttgg aaaacaagca ggggcagata gatttagata ctgtgataca
      841 gtaggagtta tgaatccttt ttctataaag aatgcaatag aaactcttta tgaaagaact
      901 aattttgata tagaaatgca tacacataat gactttggga tggcaactgc aaatgcactt
      961 gcaggaatag cagcaggagc aaattatgtt ggtgttacag taaatggatt aggtgaaaga
     1021 gcaggaaatg cagcattaga agaagtttta atggcactta agtgtgttta taaatgtgat
     1081 ttaaataata tagatactag aaaatttaga ggaatatgtg agtatgtagc acaggcatca
     1141 ggaagaatac ttcctacatg gaaaccagta gttggggata atatgtttat acatgaatct
     1201 ggtatacatg cagatggagc tttaaaagac ccacataact atgaaccatt tgacccaagt
     1261 gaagtaaatc ttgaaagaaa aatagtaata ggtaaacatt caggaagagc tgcagttgta
     1321 aataagttga gtgaatatga aatgtatatt tctccagaaa acgctaccaa gctattaaat
     1381 gctataagag ctacatctat aagattaaaa agaagtttaa tggataaaga aattcttcaa
     1441 ttatattgtg atatactagc acatgagaaa ggcacaacag aagaagaagc agttagaggt
     1501 tcatatattt aagatataat tgtttaggag gaaaatatgg gagataatat agtttataaa
     1561 ataattaaaa aacatatagt agatggagaa gctgttgctg gaagttcaat tggtataaaa
     1621 atagaccaaa ctttaacaca agattctact ggaacaatga catatcttca actagaagct
     1681 atgggaatag ataaagtaaa gactaaaaga agtgtggcat ttgtagacca taatatgtta
     1741 caacaaggat ttgaaaatgc agacgaccat aagtatatac aaacagtggc agataaatat
     1801 ggagtttatt tctctaagcc aggaaatggt atttgtcatc aagtattttt agaaagattt
     1861 tcaacaccag gagatacact tttaggttct gatagccaca cacctactgc tggaggtgtg
     1921 ggcatgatgg ctattggagc tggtggatta gatgttgctt tagccatggc aggaggagca
     1981 tactatataa aagcaccaaa agtctgtaag gtgaatctag ttggaaaatt aaataatatg
     2041 gtatcatcaa aagatataat attagaagtg ttaagaaaac aaactgtaaa aggtggagta
     2101 ggtaaagttt atgaatatgg tggagaaggt gtcaaaagcc tatctgttcc acaaagagct
     2161 acaataacaa atatgggggc tgaacttgga gcaactactt caatcttccc aagtgatgaa
     2221 aaaacactag aattttttaa gagtcaagga agagaagacg catgggtaga gctaaaacca
     2281 gatgcagatg cagtttatga tgaagagatt actataaact tggatgaatt aaaaccatta
     2341 gctgcaaaac ctcatagccc agacaatgta gatgaagttg aaaatatagg caagattaaa
     2401 atagaccaag tggcaatagg aagttgtaca aattcttctt atgaagactt aatgaaagta
     2461 gcacaaatcc tgaaaggaaa taaagtacat aaggatgtga gtttggtaat agcaccaggt
     2521 tcaagacaag ttatggagat gattgctaga aatggggctt tggcagatat aataagtgct
     2581 ggagctagaa tactagaaaa ttcttgtggt ccatgtattg gtatgggtca atctccaggt
     2641 actgactctg tgtctttaag aactttcaat agaaatttct atggtagaag tgggactttg
     2701 tcagcacaag tatatttagt aagtccagaa gtggcagcag taagtgcaat caagggagtg
     2761 cttacagacc caagagaatt tgatattaaa tttacaaatt tagatgtaaa tgagtttttg
     2821 atagatgata gcatgataat taaacctgct gatgtaggaa gtgatgtaga agtagttaga
     2881 ggacctaata taaaaccttt ccctcttaat acagagctaa gtcagtctat aggtggaaaa
     2941 gttatattaa agacagaaga taatataact actgaccata taatgccatc aaatgctaag
     3001 ttacttcctt ttagaagtaa tataccgtat cttgcaaact attgtttcaa tactgtagat
     3061 acagaatttc ctcagagagc aaaagacaat aatggtggat ttatagttgg tggagataat
     3121 tatggtcaag gttcaagtag agaacatgca gctttagcac cattatatct aggtgttaaa
     3181 ggggtaatag ttaagagctt tgcaagaatc cacaaggcta acttgataaa tagtggtata
     3241 attccaatgg agttttgtga tgagaaagat tatgaaaata tatctctttt agataatctg
     3301 gagataccaa atattttaga caatctaggt agtggaattt tagaagttaa gaatacaact
     3361 aaaggaactt cttttaaggt caaagtagaa ttgtcagcaa aagaagttga tgtattaaaa
     3421 gctggtggaa aattaaacta cactaaaaat caagctaatt aatatgaaaa gagggaatat
     3481 tgaatgtata aagtgacact tataccagga gatggaatag gaccagaagt tgcgaaagct
     3541 atgaaaaagg tagtagaagc tactggagta gaaatagaat gggaagaagt taatgcagga
     3601 gaggcagtta ttgaagagta tggtactcca cttcctgaat atattataga tagtataaaa
     3661 aagaacaaaa tagctataaa aggcccaatt actactcctg taggtaaagg atttaggagt
     3721 gtaaatgtaa ctttaagaca ggcattagat ttgtatgtca acttaagacc tattaaaagt
     3781 tttaagggga taaaatcaag atatgaagat gttgatttag tggttgtaag agaaaataca
     3841 gaagatttat atgctggaat agaacataaa ataggtgatt atgcagctga aagtataaag
     3901 ataataacaa gaagtgcaag tgaaagaatc gttgattttg catgtaacta tgttaaagat
     3961 aataagagaa aaaaagttac agctatacat aaggcaaata taatgaaaat gtctgatgga
     4021 ttgtttttag atgtgtttag agaagttgca tcaaaacatg gtgtagaata tgatgatttg
     4081 attgtagatg cagcagctat gaacttagtt ttaaatccag aaaattatga tgtaatggta
     4141 atgccaaatc tttatggaga tatactatca gatttaggtg ctgggcttgt tggaggttta
     4201 ggtataattc caagtgcaaa tattggtaaa gattgtgcga tatttgaagc tgttcatgga
     4261 agtgctccac aaatagcagg tcaaaataag gctaatccaa cagcacttat tcaatcatca
     4321 gtaatgatgc ttagatactt aggtgaatat gaaaatgcac aaaaaataga aacagcttta
     4381 gaaaaagtat ttcttgaagg aagtaaattg actgtagatt taggtggctc agcttctact
     4441 acagagtttg cggatgaggt gtgtaagtat attgtataga ttttatttag ggaaaaagta
     4501 aaatatagat tgaagaaaag aggctttctc aaaatagaga taagcctttt ttattggaat
     4561 gataaaatat atttgatttt atacaaaaga gagttcctca taaacgaaaa agttaatttt
     4621 gggatatcca ttttaatttt aaaattaatt gattaatacg caaagaaaga ttaaataaat
     4681 ttattatttt taattgaact ttcaaccaaa atatggtaaa atttaaaaag ttgaactttc
     4741 aactaaaaat gaaaatattg attatgtgaa attctataaa acagaaacta tttgacttta
     4801 gccatggtag tttcagtgga ggtgtgtttg attaagactt tagatagtaa tatattaaga
     4861 gaagtaggta ctttatctag agcagtaaat tcaataaatg atattaagta caaggaatta
     4921 aagttacaaa aaggacaatt tacatttttg acaagaatct gtgaaaatcc tggtataaat
     4981 cttgtggaat tatcaaatat gttaaaggta gacaaggcta caacaaccaa ggctatacaa
     5041 aaattaataa aggcaggata tgtagataaa aagcaggata agtttgataa aagaggatat
     5101 aatttaactc caactgataa atctttggaa gtttatgagt tgataattga agaagagaat
     5161 agaagtatag agatatgttt tgataatttt acagatgaag aaaaacaagt ggtaactaag
     5221 ttattagaaa aaatgagcaa aaacgtagaa aatgaatggt ttaaagtaaa gagatagtaa
     5281 ataaatacat taacttaagg agatattttt atgattagaa aagcgaatat gaatgattta
     5341 gaaagcatta tgaaaattat aaaatctaca gtggaagaaa tgaagactta taataataca
     5401 caatgggatg aaaactatcc attagaaaaa gactttgttt cagatattaa gaaacaagat
     5461 ttatatattt atgaagtgga tggagaagta gcagggttta tatgtcttaa ttatgaagag
     5521 ccagaagaat atttaggctt aaattggtca tctaataaaa aagcaatggt aatacataga
     5581 atggctgtaa atccaaactt tagaaagaca ggaatagcat ctaagttagt tgattttgct
     5641 gaaaaattag ctgtagaaaa caatgtatca tacttaaaga gcgatacata ttcaataaac
     5701 tcaaaaatga atttattact tacaaagtgt ggttttataa aaatcggaga aatgagtttt
     5761 ttaggaaagg agaaatcttt ctactgttat gataaaatat tataaagagc atttataata
     5821 caaggggtaa ataatagatt ttcagcatta gtaagggcat aatataacct agtatatgct
     5881 attatgaaag ggatgattta tatgattgga tttctaaaga aaagaagaag tattagaaaa
     5941 tacaaggatg ttgaagtaga aaaagaaaaa ttagataaaa tattaaaagc tgctctttta
     6001 gctccatcat caaaggggct tagaacatgg gaatttatag tggtagatga taaagaaaag
     6061 ctaattaatt tatctcaatg tagaactaaa ggtggtggat ttttcttaaa aaatgcacct
     6121 ttagctattg taattattgc agataaagaa aaaaatgatg tttggataga ggatgcaagt
     6181 atagctgctt catacataca acttcaagct catgaactag gtttaggttc ttgttggata
     6241 caagtaagaa atagaatgca tgatgataat atagaagctg ataagtacat tagagaagaa
     6301 ttaaaagtac ctagcaagta cagtgtagaa tgtataattt ctataggata tcctgatgaa
     6361 gaaaagaaag catacggtga ctctgattta gactataaaa aggttcattt taacaacttt
     6421 tagtatataa tatgttgtat taagacatta tatttttttc tattgttaat atatacttaa
     6481 aattgtaaaa atatatctga attttactaa cttatctagg ggttatgtac aaggatttta
     6541 aagataaata tagaaattaa tgtttataat cgatacataa cttgagtaac aaaatttaag
     6601 gaggttaaag tatgggtata tttaaaacaa aaatggatga ggactggaaa gtaaactaca
     6661 ttaaagagtt taatgaaatg agagattctt atgagagtaa acttcaaaaa aaacagtttg
     6721 aggtagatag tttgaaatca gaattggata gactaagaag ctataaaaat agccttaagc
     6781 caaaagaaaa acaaattact gatgatgata taaataatat aaagagttta agaagagatg
     6841 gcttaagcta taaagaaatt tcaaatcaaa caagttggag caaagcaact gtaagtaggg
     6901 tattaaatgg actttacgat tagcatatac atggggtgat ttaaattggg atgaagtata
     6961 gttacaaaaa atgcataata gattctattt tattgatgtt tatagttcaa atattaagga
     7021 tgattttgaa ttatgtactt ctaagtcaat ttgaatttac tcttgaaaat tttaatatta
     7081 taaacttaat ttcttttaca ttagttggtt tatcgttaat tttattttta aaagataatt
     7141 ctttgtataa caaggttaga aatagaaaaa tcacagaagc ttttgaagaa aataaaaaca
     7201 atatacttat tgaaaagtgt aagctgatac tttttgttgt ggttttatct ttagcaataa
     7261 ttgtaactta ttgtactaag ggatatgtac tttttaatgt aactatgatg actttgtctg
     7321 tattgatagt cccaatattt gaagagttat tttttagaga atatatatgg aactatctaa
     7381 gtaattttat aaagtcaaag agtaaaatta tctgtataac atctatacta tctggaattt
     7441 ataatatagg atacatagat gttataagaa attatgtaat attgtataac aattcaagct
     7501 acacctttga agttattatt tcaaaaatta tgataggtac tgtttttggt attgtacttg
     7561 gattagttaa gtataggttt agagatgtag ggttttgtat attattgagg agcttatttg
     7621 ctatatttat taggtagata gtataatcgg tttataaggt tgttttaaat ttaattttaa
     7681 atcaacctta ttttatttgt gttttataaa gcacttatat attaataact aataaattta
     7741 ataaaaatta tttgaatatt tttaaaatat ataaatatgt attgacatat aaatattatg
     7801 aattacaatt tatataaact aataaaaatt aaataatatt aatcaactta ttgaatggag
     7861 gaataaaaat gaaatttgtg actttttgta gtagcaatga agaaaaaata ggtgtattta
     7921 attcagaaac aaatagtata tatgaaatta atagtttagg attaagtaaa ttatatactg
     7981 atatgaatga ttttattgaa aacgtatcta caggagattt agaaaaaata aaaaacaatt
     8041 catttgaaaa cgcaaagtgt tataagttag aagaagttaa attatgttcc ccaattgtaa
     8101 gacctaaaaa agatattata tgtttaggtc taaactataa agaccatgtc aatgaaatcc
     8161 cagatggagt tataaaaaac gtagttatgc cagattatcc aatttatttt tctaagagag
     8221 cagacaaaat aattggagtg gatgataaga taagcttaca tggagatttg gtagagaagt
     8281 tggactatga atcagaactt gcagtaatca taggtaaaga aggtataaat atatcaaaag
     8341 aagatgctta tgaatatata tttggatata caatagtaaa tgatataagt gaaagagcac
     8401 ttcaagataa acatgttcaa tggtttagag gaaaaagctt agacacacat acatctatgg
     8461 gaccttgtat agtacataaa gaagaatttg aacatccttt aaaattagat ataagtagtg
     8521 tagtaaatgg agaagtaaga caagattcta atacagagta ctttatattt gatataccta
     8581 ctataataaa tgatttatca agaggaatga ctctaaagcc aggagatata atttcaactg
     8641 gaactccagc aggggttgct atggggatga atcctcaagt atatttaaag catggcgata
     8701 tagttgaatg taaagtcgaa ggaataggag ttttaaaaaa tatagttgat taatggataa
     8761 atatgccata taattttatt agtacgaata atttaattaa tataggatta atcaaactta
     8821 tgattaattt attatagaga gggatgagta tatggcaaga gaactagaat taaagtatgg
     8881 ctgtaatcca aatcaaaaac catcaaagat ttatatgaag aatggagaac ttcctataga
     8941 ggtattaaat ggaaaacctg gatacataaa ttttttagat gcatttaata gttggcaact
     9001 tgtgaaggaa ttaaaagaag ctacaggtct tccagcagca acttcattta aacatgtaag
     9061 tccagcagga gcagcagtag gggtaccttt atcagatact ttaaagcaaa tatattttgt
     9121 tgatgattta gagctttctc cattagcttg tgcttatgca atggcaagag gagcagatag
     9181 aatgtcttct tatggcgatt ttatagcact ttcagatgta tgtgataagg agactgcaac
     9241 tattatagca agagaggttt ctgatggtat aatagctcca ggatatacag atgaagccct
     9301 tgaaatatta aaaggaaagc gtaaaggtaa ctataatatt gtaaaaatag atgaaaatta
     9361 tactcctgaa cctattgaaa caaaggatgt ttatggaatt acttttgaac aaggtagaaa
     9421 tgaaatatta ataaatgaag acctattaaa agatattcca actgataata aaatttttac
     9481 agatagtgca aaacgtgatt taattatagc tcttattaca ttaaaatata cacaatcaaa
     9541 ttctgtttgt tatgctaaag atggacaagt aataggggta ggtgcaggtc aacaatcacg
     9601 tattcattgt actagacttg caggtaacaa agctgatact tggtatcttc gtcaacatcc
     9661 taaagtatta aacttaaaat ttaaaaagga tataggtcgt ccagatagag ataacactat
     9721 tgatgtatat ctttctgatg attatatgga tgtgcttgct gatggcatat ggcaaaactt
     9781 ttttgaagaa aaaccagagc ctctaactgg agaaggaaaa agagcatggc ttaaaacttt
     9841 aacaggagta gcacttggtt cagatgcatt tttcccattt ggagataata tagaacgtgc
     9901 aaaaagaagt ggggtaagtt ttatagcaca accaggtggt tctattcgtg atgataatgt
     9961 tatattaact tgtaataagt ataacatagt catggcattt actaaaaata gattattcca
    10021 tcattaaaat actgaaagta taaagataat atagattaag taaaaatcta caacaagttt
    10081 tgttgtagat ttttttattt gctgtataat tttaaataga actttatttt tagatattca
    10141 atttggaggt tgatatggct ttaaatataa gaaactatag cctattatgt aatcaaggaa
    10201 cagctaaatt taatgaagat gtagtcggta taaatccatt tggggcatgg gttttagatg
    10261 gtgctacagg acttaatgga aaaaatttag tgtcaactga aagtgacgca aggtggtatg
    10321 ttcagtggtg gaataggtat ttatataaaa atataaataa agaagaatca ttaaagagta
    10381 ttattaatac tggaataata gaagtaaaaa aagagtatga actaagatta aatgggttta
    10441 aggttgaaaa attagattta ccatctagtt ctatagttgt tgtaaaattt catgaaaata
    10501 aagtagagta ttttttatta ggagattgtg ctttgtttat taaaaatgga gattccaaag
    10561 ttataaaaga taggagtatt tgtaaatttg ataatactgt atttgatgaa atgagtaaac
    10621 tttctaactt ggaagagatg gcttttgatg agattagaac tagtgttatg gatacaatag
    10681 taagcaatag attgaagaaa aatacaaaag agggctattg gatattggat tttgatgagg
    10741 aagctgtgga aaattctata tatggataca ttgaaataaa aaaagatttt caattgatgc
    10801 taacgagtga tggttttaca agtgcatgtg atagatataa tctaataaaa gaagaagaat
    10861 tgatacgtat agcagaaaaa tttggtatag gatatataca taataaagta agggattttg
    10921 aagataatga ctataaagcg gttaaagtgc caagatttaa agtaaaagat gattcatctt
    10981 gtttatattt agatatatat aatgattaga ctgtataaaa ctatttaatt ttagaaagga
    11041 ggcaagtgaa aagtgaaaat tcttcatata ataacacaaa aaccaaatag tacaggtagt
    11101 ggtatatatt tgtctggtat gataaaaggg ttcgaaaaaa tcggtcataa gcaagctgta
    11161 attgcaggta tagatgtaaa tgatgatgta aattgttttc caagtgaagt aagtttttat
    11221 ccagtaaagt ataattgtgg ggagttaaat tttcctgttg taggtatgag tgattctatg
    11281 ccatatgaaa gtacaagata taaagattta aatatagaca tgataaatag attgaaatat
    11341 caatttaaag taaatataga taaggctatg aatgatttta aaccagaact tataatatgt
    11401 catcatttgt acctcttaac tgcatttgtt agggaaatgg taaaagatat aaaggttatg
    11461 tctatttgtc atggaacttg tttaagacag ttaaatacca ttgatttaga gaaagaatac
    11521 ataatagcaa atataaggaa attagattta atatttgctc ttcatgaaaa tcagaaatat
    11581 gatattataa agacttttgg agtaagtgaa agtaaagtag ttgtaattgg tagtggttat
    11641 aatgatgata tattttataa taaaaattat aaaataaagg atgataaaat aaaaatagta
    11701 tttgcaggta agatatgtaa atcaaaggga ctgattccat ttataaaagc tatatctaaa
    11761 ttaaaatata gtaaagattt aatagaagtc aattttgcag gtactggaag cgatatcgaa
    11821 tcatataatg agatagttaa actggcaagt aagtctccat ttaaaatgaa tttcctagga
    11881 aagttagaac agagagattt agctgagcta ttcaacaggt cacaaatatt tgtgttacca
    11941 tcattttatg agggattacc agttgtagtt ttagaagctt tatcttgtgg cacagatgta
    12001 atcactactg atattcttgg tgttaaagag tggattggta gtgagattaa taattctgga
    12061 aagatagaat atgtttctct accttttatg gagaaagaag gtattccaaa agatgaagag
    12121 ttatatgatt ttgaaaataa tttgtataat gcaatagatt ctaagataca atctttattg
    12181 aataactcaa ataagaaaac atctgtagat atgtcaaaaa aaacgtggga tggcttagca
    12241 tatagaataa atgaagttat tttaatggat gaattgtgtt tagtctaaaa ttatttaaat
    12301 tataaaaaag tgtaactatt tttacactat ttttaaatga ttttatatta tactaatact
    12361 aaatatattt gttttaggga ggtaatttat gaggattagt aaaaaggtat tggcgttagg
    12421 tatttcagca ttactgttaa gtgttagttt tccaacatca ataaacgcac tagataagat
    12481 tgaaaatatt caaggagtag ataaatatga aacagctggg cttatttcag ataagcaaga
    12541 ttttacaaca gcagttctta tcaatgcaga ctctacaatg gtagatggga ttgctgcaag
    12601 tggtcttgca ggagtaaata atgcagctat tttattaact aataaggatg atataccaga
    12661 agcaacactt caaagactga atagagttac taagatatat gtaataggtg gagaaaattc
    12721 tataagtaaa gatgtagaaa aaatgttact tatgagaaga atgcaagtta taagaattga
    12781 tggtgtagat agagtagata caagttataa aattgcaggt gaaatagaaa aaattaaaaa
    12841 cagtgataag atgtttttag taaatggatt taaggatgaa gctgatgcag taagtgttgc
    12901 atctgttgct tatagagatg gagctcctat aatattgaca aaagatatac cttcagcaga
    12961 agaagacaca gacttagacc catggtttgg agtttctcct gttccagtat atgctattgg
    13021 aggagagtct acattaagtg attacatagt gagcagatat agagcaacta gaattggtgg
    13081 tgttgataga tatcaaacta ataaaaatgt tattgaaaag ttctataatg gagcaaaaga
    13141 gttctatata acaagtggag atgatttagt ttatgcttta gttgcatcac cacttgcaaa
    13201 aaatgctcct gttgttttag tttcaaataa aagtgataag agtatattaa gtggagctag
    13261 taaagtaaca gcaataggta taagtgataa gagtattata gagcaatgtt tggatgctgt
    13321 aaagaagtaa tggagtgtta ttagtaaaat gaatatatac attgaaaatt agtagattgt
    13381 tcattttata atggtataaa atatatggga agaggctatc aaatggagat aagcctcttt
    13441 ttcattgtta aaattatgaa aagatacttt attttatata aaaaagtatc ttatgaacta
    13501 aatgtctatt ttgagacact atctactttt cttatattat attatttttt atatggaata
    13561 aatttcataa gtattatctt cctttaattt ttctaaccaa accatctcta aaatatctag
    13621 ttcttctaaa tagtctttct ctgttttgtt atcatcatgt tttataagtt ctaaaacttc
    13681 aaatgtaaat gctttttcac catatttttt ccattcatta tttaattctt ttatcataca
    13741 tgagccagca ccaagctgaa atttgagaga gttaaatttg ctttttatgt cattactttt
    13801 tccaaggtaa atctttttag taatatcatt ttttattatg aatacacctg tgtcaaattt
    13861 catttctttg tataattgtt ttaattcacg ttttctatcc atgattttag atacctctct
    13921 ttataattga tatgtaatat gtaagtgtaa aaatatatta catatcaatt ataaagagat
    13981 taattttata tgtaaatagt ttttataaat ttaattatga attagtcatc aataaacaag
    14041 aaatttagct gtaaaaatcc attataaagg ctattataaa ttttaatatg ctaaaaatat
    14101 aaaaagaata gttgacagtg tagaaaatat ggaataaact aaaagtgtaa tagtaatatg
    14161 aagttatata ttacattgaa aggtgtgaat gattattatg aataaaaaaa tagaattaat
    14221 agggaatttt gcaagtgatt ggattaggta tagtgattat gaatataaaa ttactgaaga
    14281 agatgaatta tatatagttc caacagaaga tgctgtgttt accatgtata acccatttga
    14341 tgtagcagat gatataatag tagatataat tcgcatagga caagaggcat tacaagatat
    14401 atcaaaagag acaaaagaaa tgaaactaaa gaaagaagta cttgaatttg taaaaaagta
    14461 tggattattg ggtttaatat attcaagtgt atataataga gatatagttg gagaagaaag
    14521 agtactgatg attgaaaaga attatattac aaaagagaat atattgagta cagatgaata
    14581 tgtaaacatg tttataccat ttgcaagtga tgaagatgtg tattttaaaa agtatagaag
    14641 gggtatagat gtatcaaaga gagaagaatc tccaaagttt tttggaaaga gaccattgat
    14701 tttagattta gtattttcaa agttctacac tgaacaacta gattggattg taagttttgc
    14761 taaagatatg tgtaagcatt ttaatcaaat ttgtgtatat aaaaatacat ctaatctatt
    14821 aactgaaagt gttactatta tgtctggagg gtttaatcct caaaagatag gattttctat
    14881 aagccaatta gataaaccaa ttattgcatg ggagtttgat tctttgaaaa cagctattga
    14941 gactatctat gcctttgcaa ttacaagtga accttcttct ttaaataaat gcaagtactg
    15001 tggtaaaatt tatattccta caaattctaa atctcaatac tgttcacctt cttgtagaaa
    15061 ttgctcaaat gtaaagaaaa gtagaagtag agccaaaaaa gataaataaa attaataaat
    15121 atatcattgt ttagatttta gtaaataact actgaattaa aagttgttat agaaaattat
    15181 atatctaaat gatggtattt ttttgttgag aaaattgaaa agtttaattg agatagtaat
    15241 tttgagttga caaaaaccac ttttaacact actattataa gtggttggta aaataatata
    15301 cattaattta agtatagcat aaaaaacaaa aaaagtcaat ggaaaaaata aaaaaggaga
    15361 atttaaaaat gatatcacct attattttga gttctataaa tcagaattta aaggaaatag
    15421 aaagaaatga actgcttgaa actaatatag aatctggaga ttatggtcta gctctttctg
    15481 aatctgatgt aaaagatata ataaattcga gagataatac tttaaagggg tatggaagaa
    15541 tagaattaga tataaaagtt acaaaacagt taatagaaaa tatatataca tcacaatata
    15601 caaatgtgga caattattta gaggctatta atgatatgca agaaattttt tattatttaa
    15661 aaaatgaaac tgatgacaag atatgtgatg atgagattat agaaatactg ggtgaatttt
    15721 atgaaaaatt ttcaggcaat atggacaatg taagaggaga agcagacgaa tttgcaaaga
    15781 aatttaaatt tggagaagtt taatatatga taggagagat tttgtatgtt aaataattta
    15841 agtaatatta atataaacga aaataattta ataaagaacc aatattccat atctctactt
    15901 aaggaatgtc taaattgtaa agtgatagat gaaagagaag tatataatat acaacaagaa
    15961 gtatctctaa tacttatgga cttgattaaa aaatatacaa atggtcaaag cacatcagta
    16021 aaaacagaag ttgccgaaaa actgttgatt tcaatatggt atgctattga tgcatatata
    16081 aataagcttg gagatataga aaaaagagtt gtggagttga ctgctaagaa tgttaaaaaa
    16141 gtgtaccttg gaggcattga aatattagag gaagagttag ttaggctaaa agatttttat
    16201 aaactaatga tgagtagaaa attggatact aattcaatag catataatga taccttgatg
    16261 gagttatcaa gtttctttaa aagttatatt gtaaaatttg aagctcagga cgttccagta
    16321 agtatagatt atccattggc actagatgat atggatgtta agggtattta ttatgtgaag
    16381 aattatattg agagtataga tatagaaaat agattttgta acctatttaa gaaaaaagat
    16441 agagaaaaat tattttatga ctatgggatg acttataaaa tagattgtga tgttatactt
    16501 gtaaatttat ttgaacttat tatgaataat tgtatttttt ctactatttt aggaaatgaa
    16561 gtgactaatt tagaaatttc aaaatatgag tatgaatttt tagaaaaaca atttaaaaat
    16621 atgtacaata atattactga agataaagtt atagactctg aagaaagtaa tataattgaa
    16681 ttgattgaag tagatgatag ttttaacact gaagtagata gtaatttgga ttataatgat
    16741 tttgaagaaa ttaacagaga aattagaata aataaaaaaa taactttact acttatggaa
    16801 gcaattgaag tattaataaa aagattaagc atagaagatg aagatgtaat aagatatatt
    16861 aaaaaatatg aaaagatatt tattgaatct gtgctaagct caataaaaag taacactttt
    16921 aaaagtatgg taactgtgag taaaaataaa aaggaacact tagaagatta tattgttgat
    16981 gatgaaagta aattggatga tgaatcgttt agagagatat tcaatgagat attagatagt
    17041 acatctataa ttgaaaaaat aagaataata aaggaaaata tcaatgctaa aaaagacttt
    17101 atcgatattc ttgaatctga atgtttattt ggagaagagt atttaatgtt gtttgcatca
    17161 ttaagtgaat tagaattggc aatattgggt agtgtagtat tttatgaaga tattagaatg
    17221 agagaaatta atatattaga atttatgtta aatgagaaaa ctgaaactac tttatggaag
    17281 atagagtaca ttaaatttat gaagaggcaa agtgaagata agatatactc catagaagag
    17341 catatgaata aaattaatta acaaaaaatt gtgaataaat agaatgttag tatataatat
    17401 aatctgtaaa gcatatcaaa aatacatata tttggaggaa aattatgaaa gagtatatca
    17461 taaataatgt tgaagaaata agagaagaat taattgattt atctaagaaa atatgggaaa
    17521 atccagaatt agcctttgaa gaaaagtatg caagtagcat tcaaaaagaa tacctaaagt
    17581 caaaaggatt taaaattgaa gaagtagaaa atttacctac tggatttata gcaagttttg
    17641 gagagggtaa acctgtgatt ggcatacttg gagaatatga tgctttacca gagctatcac
    17701 aatgtgtaag tgcagaaaga aagccattgg tagaaggaaa agctggacat ggatgtgggc
    17761 acaacctgtt gggtgtagca ggtgtaggag cagttgtttc tataaaaaaa ttaatagaag
    17821 aaaataaatt taatggaaca ataaaatatt ttggttgtcc tgctgaagaa gaaggtggag
    17881 gaaagacagt tatgtgtata aatggctgtt ttgatgatgt agattgtgca tttacatggc
    17941 atccttttga tataaatgca ccttggagag gtggaagtct ggcaaactta tctgtaaaat
    18001 ttaaatttaa agggataaca gcccatgcag ctcaagctcc tcataatggt agaagcgcac
    18061 ttgatgctgt tgaaattatg aatgttggag ctaattattt gagagaacat gttattgact
    18121 ctataagaat gcactatgtt ataactaatg gtggtggaag acctaatgta gttcctggat
    18181 ttgctgaaag ttggtacttt attagaggta aaaaagcaaa ggatgcagaa cacgttcttg
    18241 atagattaat aaaagtagct caaggagcag caatgatgac agaaactgaa atggagtata
    18301 aggttacaga tggaatatat gactatatac caaaccaatg tttgactgat ttagtttatg
    18361 acaatatggt ttttgttggt tgccctaaaa atactcctga agaagaagaa tttgcaaaaa
    18421 agttgtgtga tactcttact agagaagaaa gattaggtgt agcaacatca ttacaaaatg
    18481 ataaatctat tgtagaaagc tatatacaca aggaaatagt tgacggtgac aaagataaag
    18541 gactagctgg ttctactgat gttggagatg taagttatgt aataccagtg gctcaatttg
    18601 caatggcagc ttggcctgtt ggaattgcaa gtcatacatg gcagtcatgt tcatcagcag
    18661 gttcaaatat aggattttct gctatgataa attcagctaa agtactggct tgtagtgctt
    18721 atgatgtatt tatggatact aaaattattg atgaagcaaa aattgaattt gataaatcat
    18781 tagatggaca aaaatttaaa ccattggtat aattttgcta ataaaatatt tctgggggga
    18841 atagctatga gagaaaaagt tgaaaaagtg cttgaggaaa agataaaacc agtattacaa
    18901 agagatggtg gagatgtaga gcttatagat gtaaatgaaa atggtgtggt tttagttaga
    18961 ctacaagggg catgtagtgg gtgtccagga gtgactatga caatcaaagc tattattgaa
    19021 aatgttttgg tgagtgaagt tccaggagta actcaagtat taggtgttta atagttagcg
    19081 tttattaaat gtatgttata cataagtatt taataaagaa gtaaaaaaaa tagtgaagca
    19141 atatatatga aaaagtatga gaaagataat aaaacattat agaaataatg aaatatttca
    19201 tatgtatatg aagaaataag aaaaaatagt gaagcaatat atatatgaaa aagtatgaga
    19261 aagataataa aacatttata gaaataatgg aatatttcat atatacatat gaagaaatag
    19321 taaaacaata tatatatgaa aaagtgtgag aaaataataa aatactatag aaacaattaa
    19381 atattctata taggtattaa gaaacatgaa agaaataatg gagtattata aataaatatg
    19441 taaaagtgtg aaagaaggat gtagataaat ttgtcttata caaatttacc tacagtattt
    19501 cttacacact ttttatttta ctatccagcc ataccaataa acatacctat aaaatatgga
    19561 actaaccata tagtccatac aactatacta aacttatgaa agaatttttt cttttcctca
    19621 tcatctttgt ataggacaaa agtagcccaa cttgcatgaa aaagcataag cacaattgca
    19681 agaagacctg taatactatg aaggttttgt gataaagcag attttacttc aaaagtatgg
    19741 ctgttggcta tgttactcat tgtaaatgtt cctaaagtat caaatataaa accaagccaa
    19801 aatataatta catgtttctt ttttaaaatt tttgcctttc tttctccaaa tacacctata
    19861 gtgtagaaaa ttaaagctga tgttataaat actattgcaa gtattaattt ataattcata
    19921 attatctctc ctttactttt gccaatatat ttctaagatt ttttactaag tcactcaatt
    19981 cgttttcatc acaattttta aaaatatcat caaaactttc ttgcatttta attttaaaat
    20041 ttgtggcaaa ttcaaatcct gttgttgtaa acttaacgta tgtatttctt ttatcattag
    20101 atttcttgaa tttttctata tatccaatct gttctaatct gctgattatg cctgaaaccg
    20161 tacctttagc taaagacatt tcatcacata gttgtgatat tgtaagttct tgattatgag
    20221 ctatcagttt tataactata atctgttggt gtgttaatcc attttcttta aaattttctt
    20281 ctactgtgta catagtttta gaataaagtt cttttaagag catggctatt ctaaaacagt
    20341 cataattact tttcaataaa atcacctctt aaatggtttg catacaaact aatataatat
    20401 acttttctta tatagtcaac ctaaaatttt ataattttat agaaaataat gaagaataga
    20461 atataaaaat tttattttag gtataaataa aataatttga tgaaatttta acaattttta
    20521 aaaagtttgt ttacacagtt aataaatgat gctaaaatta actcatagat aaatatagaa
    20581 aatttaattt tgtttaatga taatggaacc acgaaggttt taacgttact ttacgtttgc
    20641 ttttatgtgg ttttttttat tgcaacaaag gggggttggg gtttgttaaa ggatatactg
    20701 aaaaagttgt tgcagtttat tttagtaatg tttttattat cttttattgt tttttacatg
    20761 gcaagacttg ctccaggaga cccattaatc tcttactatg gggatggagt agaaagaatg
    20821 agtacacaag aaaaagaaaa tgctatgaaa aaacttggtt tggatgaacc aatatacagt
    20881 caatatataa aatggatttc aaatgcatca aaaggggaat ttggaatttc atttaaatat
    20941 aaacaaaatg ttacttctgt tataaatgat gtctatataa acactataat attaggtggt
    21001 tcaggatata tacttacctt tgtgctagcc ttattgttag gaatattttg tacattacat
    21061 gaagataagc tcattgatag aatcatatgc aaattaggaa caataaccaa ctgtattcca
    21121 tcattttggg ttgccttagt actcatactt atatttagta taaacttaag tatacttcca
    21181 agtagtggtg cttattcaat gggagaagag tccagtatat taagtaggat atcacatcta
    21241 atcttacctc ttacagtact tatattaagc catctatggt attacacata tatgataaga
    21301 aataaattac tagaggaaat aagagaagat tatgtgcttt tatgtaaagc aaaaggttta
    21361 aataatagaa ctattgtttt taagcattgc ctgagaaata taatgccatc atatattagt
    21421 ataatggcca tttcgatacc tcatatacta ggaggaactt atgtagttga aaaagttttt
    21481 tcttatcctg ggttaggaac actttgtttt gaaagtgcaa agtatcatga ttataatatg
    21541 ttattagttt tatgcttaat aacaggggct ttagtagtat ttgggaatat gttagctcaa
    21601 attataaaca ataaaataga ccctagaatg aaatatgata gaggtgatac taatgaagcc
    21661 acaatatagt gattttgaaa ttgtaggaga aaattatatt ttagtagcag aagatgaaca
    21721 tatagaaaca aagaaaacct tatctaaaaa aattaaagaa ttaccatata tatcaattat
    21781 tattttatca atcatagtca ttggaagtgt attctcatct tttataatga cacatgaacc
    21841 aacatacatg gatttagcaa gttctaattt agctccaaat aaaacttttt tatttggaac
    21901 agactcaatg ggtagagata tatattctat gatatggtat ggaggaaaaa tatctttatt
    21961 tataggacta ttttccactg taatatcaac tgttatagga attgtttatg gtagtataag
    22021 tggttcagca tctgaacttg tagatgatgc aatgatgagg tttacagaaa tcatacttag
    22081 tataccttca atattaatta taatatttgt acaagctata cttggaaatt caaatccagt
    22141 atctatgtcc atagtaatag ggataacaag ttggatgaat atatctaaga tagtgagaac
    22201 agaagttaga caaataaaaa atagcgaata catactagca gctaagagca tgggaggagg
    22261 attcttctat gtattaaagc aacatttact tccaaatttt gtggcatcaa taatgttcat
    22321 ggttgtaaca aacataggcg cagctattgg tactgaatcg acacttagct ttttaggaat
    22381 tggtttacca atagaaattg tttcttgggg aagtatgtta tctttgtcag aggaagcatt
    22441 actttcaaat agatggtgga ttatactgat tccgggtata tttttggtta ccacattggt
    22501 gtgtataaca aatataggta attatataag aaagaataat aataaaaaat ctagtaattt
    22561 ataaatcagc atttgagtat taaataagca aatactgagg tatttgaaat atctatttaa
    22621 ataaatgggg tcaaagcttt gaaaaatatt ttataaaaag caaaaggggg agcatcatga
    22681 aattaaagaa gttaaaagtt ttaagtttag taatgatact tagtctaatg gcaggttgtt
    22741 ctagtggagg agacaaagat aagaaggcag atacgcctaa agatggaaag gtgcttgttt
    22801 atggaagtaa tgactataca agtataaatc ctgcactata tgaacatgga gaaataaatt
    22861 cgttaatatt taatggatta acagctcatg atgaaaataa taaggtggtt ccttgtctag
    22921 caaaggactg gaaatttgat gaggcaacaa atacatatac ttttaattta agagatgatg
    22981 ttaagtggca tgatggagaa aaatttacag caaatgatgt taagtttaca atagaaacta
    23041 taatgaatcc agataatgct tctgagatag catcaaatta tgaagatata acaaaaattg
    23101 atgtggttaa tgataatact ataaaaatta ctttaaaagc tccaaataca gcaatgcttg
    23161 attatttaac agtaggagta ttaccaaaac atgctttgga aggtaaggat atagctactg
    23221 atgaatttaa tcaaaaacca ataggtactg gaccatttaa acttgaaaaa tgggacaaag
    23281 gtcaaagtat aacacttgtt aagaatagtg attattttgt aaaagaacca ggattagata
    23341 aagtagtctt taagattgtt ccagatgata aggctaaggc aatgcaatta aaatcaggag
    23401 aattagacct agctcaaata actcctaaag atatgtctaa ctttgaaaaa gacgaaaaga
    23461 attttaaagt aaatataatg aaaacagccg actatagagg tatattatac aattttaatt
    23521 ctaaattctt taaagataaa aaagctaaag gattaccaaa tgctttaagc tatgcaatag
    23581 atagaaaagc aatagttgac agtgtattat taggacatgg tgtaccagca tattcacctt
    23641 tacaaatggg accatataat aatcctgata tagaaaagtt tgaatataat ccagaaaaag
    23701 ctaaacaaga aattgaaaag ctaggttgga aattaggttc tgatggaatc tatgaaaaag
    23761 aaggtactaa gttagctttc gagataacag caggtgagag tgaccaagtt agagttgata
    23821 tggctaaaat atgtgcacaa cagttaaaag aaattggtgt tgatgctaaa gctgttgttg
    23881 taactgaaac agattgggct aatcaagatg ctcatttaat aggttgggga agtccatttg
    23941 acccagatga ccatacatat aaagtatttg gaacagataa aggtgcaaat tacagtgctt
    24001 actctaatcc tactatagat aaaatacttc aaaaagcaag agaaacagaa gataaagatg
    24061 aaaaattaaa gttatataaa caattccaag tagaaatgac taaggatatg ccttatacat
    24121 ttattgctta tatagatgca atatatgttg gaaaaccaaa cataaaagga ttaacacctg
    24181 atacagtttt aggtcatcat ggtgtaggta tattctggaa catagctgac tggacaattg
    24241 aataatactg aaattaatta gaaaccttag ggataaaaat atatccctaa ggtttgaata
    24301 gcataggggt tgatggtttt tggaacattt attggaggtt aataatctat ctgtaagttt
    24361 taaagtagaa gaaggagaag ttcaggctgt aagaaatgta tcttttaatc taaaaaaagg
    24421 tgagacattg gctatagttg gagaatctgg ttgtgggaaa tctgtactgt gtaagagttt
    24481 gatgaggata ctcccataca atggatatat taaaaatgga gaggttttac ttaaatcaag
    24541 tgatttggtt aagaagtctg aaaaagagat ggaagatata agaggaaaga atatatcaat
    24601 gatatttcaa gaccctatga catctctcaa tccaactata tcaataggaa agcaaattgc
    24661 agaagctgta atcattcatc aaggtataag taaaagtgag gcaaaaaaga gagccataga
    24721 gcttattgaa ttggttggaa ttgataatcc tgagaaaaga tttaaacaat ttccacatca
    24781 tttttcaggt ggaatgagac aacgtatagt aatagctata gcacttgctt gtaatccaga
    24841 tgtattgatt gctgatgaac ctacaactgc tttagatgta actatacaag ctcaaataat
    24901 tgatttaata aaggatttac aacataaaat aggtttgtca ataatattta taactcatga
    24961 tttaggagta gttgcaacta tagctgatag aatagcagtt atgtatgcag gaaagattgt
    25021 agaaatagga actgtagagg atatatttta tgaccctaga catccatata cttgggggtt
    25081 gttgggttca ttacctactt tagattcgca ggatgactat ttatataata tacctggaat
    25141 gcctccaaat ttattgaacc caccaaaagg agatgctttt gcaataagga ataaaaatgc
    25201 acttaagata gattatgaaa aagagccacc aatgtttaaa attaatgata cacatagtgc
    25261 agcaacttgg ttattgcacc cagatgcacc tgaagtagat gtaccagtta gagtaaattg
    25321 tggaagggtg atttctaatg aatagagaaa aaatactgga aataaaaaac ttaaagcaat
    25381 attttcattt ggacaaaagt actactgtaa aagcagttga tgatataagt tttgatatat
    25441 ataagggtga gatatttgga ttggtaggag agtcgggttc aggaaaatct acaactggta
    25501 aaactataat aagactacat gaatctactg gtggagaagt aatttacaaa ggaaattgca
    25561 tatcagataa aaaaacgtac aaatttataa aaaaagatgt aaacaaaagt atgcagatta
    25621 tttttcaaga ttctacttca tcattaaatc cacgtatgac aattgcagat ataatttcag
    25681 agccactaaa aattcaaggt atctgtaaaa ataaaacaga tagaatgaat aaagtatatg
    25741 agatgctaaa gctagtagga cttgatagaa gttatgcaaa taagtatcca tctgattttt
    25801 caggtggaca aagacagcgt attggcatag cacgagctct ttcagtagac ccagaattta
    25861 taatagctga tgagcctata gcttctttgg atgtgtctat acaagcacaa atagtaaatt
    25921 tatttaaaaa attgcaacaa gaaaagaatt taacttgttt atttatagct catgatttat
    25981 ctatggtgag acatattagt gaccgtatag gagttatgta taatggaaaa ttagtagaat
    26041 tggcagattc aaatgaattg tataataatc ctattcatcc atatacaaaa tcactacttt
    26101 ctgcaattcc tgttcctgac cctagatatg ctaagtcaag aaatagaata gagtataatt
    26161 ctaatggata tgattgttca aatgaaaagt cattaagttg gattgatgtt tcagatggac
    26221 attttgtata ttcttctaaa tcagaaataa ataaatatca acaaaattta aaagttgttt
    26281 agtataaaaa tacttgaaca ggtatttatt tgaaatacaa actaaaaccc tatttttgga
    26341 gaaattttaa aactactcca aaatagggtt ttttatttct acttttcaaa tataataaat
    26401 tcaaatataa taaaattaaa aacaagtaaa gtatgttgtt aagaaagtac tataaaatta
    26461 aaaatagtaa tgtagaaaaa atgagcaata atcttatttt ttctacaata attttctata
    26521 atttaaagta aggaaagttt gataaattat aaccttagtt aaagaataag agtttattaa
    26581 aaaataaagt gtgtataggg gttttagtta ataaaatact ataatgtagg ggagcttgta
    26641 atgatatata aaaaagataa agtaatgaaa gttttagaat catcatatag ggaaaatgaa
    26701 aaagggatta cagctaacca attatcagaa aagacaggaa ttgcaagaaa caatataagt
    26761 acatatttaa accaattatt caatgagggt atggttacga agataaaagg aagacctgtg
    26821 tattatatcc ctgcaaatct taaccttaac aagaatgaat tgcttgatac acaaagtgag
    26881 ttgcttggca taaaaaaagg aacaaaagta gaaaacaaaa taaaaaaaga tagttttgaa
    26941 acactaatag gtaaagaaca tagtttaaga cctataatag aaaaatgcaa ggtcgcaatg
    27001 ctctatccta caaatggact tcatactatt atctatggag aaacaggagt aggaaagagt
    27061 atgattgcta gatatatgta cgattattct atagatagtg gaattagaaa aaataaagct
    27121 ccttttgtaa catttaattg tgctgattat gctaataatg cacaattact tatgggacat
    27181 atttttgggg tagaacaagg agcttataca ggtgcagaat cttccagaaa aggtcttttg
    27241 gaaattgcaa atggagggat actattttta gatgaaattc atagactacc agcagaaggt
    27301 caagaaatgt tgtttacttt tatagataag ggaacattta aaagactagg agatgcaacg
    27361 aaagaaagag agtctaaggt attaataata tgtgctacta cagaaaatcc gacatcaaca
    27421 ctattagata cattcaatag aagaatacca atgaaaatag aaataccatc actgagagat
    27481 aggacaatga ttgaaagaat ggaattagtc aaaaattttt tcaaggaaga atcaaaaagt
    27541 atttctattt caataaaagt acataaagaa ataattaaat cactattact ttatgattgt
    27601 aaaaataatg taggtcaact tcaaaatgat ataaaattag ctgttgcaaa tggataccta
    27661 agatataaaa gagataataa agaaccagtt tatatagaga aaaaatattt tgataaatct
    27721 ataaatgaag tgagtgatga ttatagagag aagtctatta aagcagatga agttataaca
    27781 catggaatag aatattttgt atttacgtca ttaggagaag aagaagttat taactacaat
    27841 gatataaata ttattaatgc agtaaatact aatcttaata aatctgtaga aatgaatata
    27901 gcagatgctt ctctatttaa taatgttaag tttaaaagca tgtgtgaatc aataagacaa
    27961 attattaaag aagatgaaga aatagacata agtgaatcaa tatttaagtc aatggcaatt
    28021 tatataaaaa gcgtattgga taaaagtagc tctacaaaca acatagattt gaatcaaatt
    28081 agaagaaata acagaagtga atttaaaaca gcactaaaaa tagttggaat aattgaaaat
    28141 gaatttgatt tatttttatc tatagaaact gtagcatata ttacattatt catagtacaa
    28201 gctaaacaag atgaacaaaa taaaatagtg aataacatta atattatagt tgctatgcat
    28261 ggagaaacta cagcaagtag tatggtaaaa gcagttggtg atattattgg aaagtgcagt
    28321 gctatttctt tcgatatgaa gttagataaa agctatgatg aagttattgt agattttaaa
    28381 aatttaatta ataatataga caataaagat gtattactat ttacagatat gggttcatta
    28441 aactcttttg atgaaattat aaagaaagaa aaaaagtgtg gagtaagagt aattcctatg
    28501 gtgacaacat taactgtgtt agaagcagtt cagaaggcca atatgggatt acctttaaat
    28561 gacgtataca actctataac taacacgaga aagtactatt ttggaactaa tgaaattcaa
    28621 aataaagaaa atctgtctaa aacaattatt atagcatcac atgtttcaga aggtgtagat
    28681 aataaaacaa gaaaaatatt agaagaaaag atgagtaggt acttagatgg aatagatatt
    28741 atatctgtcc catataaaac agaaaaagat ttaagtttaa atattacgaa acttaaagaa
    28801 agtagtaata ttgttgcagt aatcaatgaa caaagaatta atattagagg aattgactat
    28861 attagcaaaa aagatataga taaggatgaa aatatcaata aattaaaaaa tattataaag
    28921 ataagtatag gttatgatga tgtagttgaa ggtttaaaga catccttaaa aagctctaat
    28981 tataatagga tatttaaaga tataaaatat gtgtctgatg aattgttttt agtatttaat
    29041 atagaaaaga aatacgataa agtaattgga cttatgatgc atttagcttt catggtagat
    29101 ggattgattg gaaatactag agaaattgaa aagcttgata aagaaaaaac acttgattat
    29161 cacaagagcc taagcaaaat aaaagatata gtatctcaat tagataaaaa atataatata
    29221 gaaattaatg aaaaagagtg ctatcaaata ttattaatat tagaatatgc agaaataatc
    29281 gaaaaagatt accaatgagt ataaaaactt atttggtaat tttttttagt ctaaaataat
    29341 attaatatta gacacatata aatatactta gacaaagtat ctaagttttg atgataaaaa
    29401 tgattgaaat aacagtgttt taaagtgtct aaaaaaactg gcataatact tgcttatatt
    29461 attaaatgag taatataaat aattaaaatt taaataaaaa ggagtaaata atatgcaaga
    29521 taaaatatta agagataaaa aggcaaatga cccatgggca agaatgacta caagaaacgg
    29581 atttagtgca gatgaaataa tatcgtcatt tcaaaaagct ataagaagaa atatggtgga
    29641 agaagcttgt gaatttgctt atgaactata tatatcatca ccagaattag aagataagct
    29701 atggagaagg atacttacaa tatcagttga agatatagga atgggggacc catcagctgt
    29761 aataatcata aataatttaa atcaagtaag aaaggaatat tcatatgcag atggagacag
    29821 acctttattt ttcatacatg caataagata tctttgtgca tgtgagaaag atagatcaag
    29881 tgatttatta aaaaatataa ttataaaagg atttgcaatg ggtaaagttc cagaagttat
    29941 ggacgtggca cttgacaagc atacatatag aggattagaa atgggaaggg attcattcca
    30001 ctttttaaat gaagctagta tagtaatacc agaaaaagaa gtagataatg attataaaga
    30061 aagatactta aaaatattag aaaaatataa gcaagaagaa gttatagata cggctttcaa
    30121 gtttaatcat tggcagtact aagaattaga gtaaatatta ataagaatta aaataaaata
    30181 ataagaatta aagtaaaaac tgataggaat tagagtaaga attggctgat aaaaaattag
    30241 aaaataaaag aggttagata ttgtaggagg gtaattatga atattttatt agtatgtgca
    30301 aatggagctt caacaggtgt acttgtggaa aagatgaaaa gtttttgtag tgagcatgaa
    30361 aagttaaaaa ctaaaactat aaatatagag gcaacatcat ttgaaaattt aaaatcatac
    30421 attgaagcta atgataccga tgtagtactt gtagcaccac aaattaggtt taaggaagat
    30481 gatgtagttg aagcttgtaa gaattacaaa atagcagttg gtttaataga tactaagcat
    30541 tatggtcgta tggatgctcc ttctgttatg aagtcggcaa tcgaattata taaaaataga
    30601 taattggggg gaataaaaat ggaagcactt caaaataatt taagaagatt tcttcttcca
    30661 atagcacaaa agattgaaaa acaaaggcat cttcaagcta taaaagaagg tatgataagc
    30721 attaccccaa taataattgt tggttcttta agtatgttat ttatggcatt aaacaatatg
    30781 ttacctgaag gaagtgcaaa aacattatta tctgaaaata tggatacatt acttatccct
    30841 aataaattta ctatgagttt attatctata tattcagcat tttttatagc tcaggcacta
    30901 gctaaaaaat ataatcttaa tcatgtagaa ataggtatga cagcagttgt tgcacaactt
    30961 gttgtatgtg gacaagtagt agatggtgta ttagatacaa gttatttaga tgcacaaggt
    31021 ttatttgtaa gtatattagt agcactttta gtagttgata ttactaagtt tatgaatgat
    31081 aaaaatctcg taattagatt tccaaaagaa gtacctagtg tagtaaataa aagttttaga
    31141 aacttaactc caatgatagt atgtataatg ttatttacag caatagcagc aataactaaa
    31201 aatgtctcag gtcaaccatt accagctatt ataatgaatt tcttagcacc agctataagc
    31261 agtgtagata atgtttttgc agtaactata atactattta taactcaatt attatggttc
    31321 tttgggcttc atggagcagc aataacttca agtatatgga tgccaatagc agctacatat
    31381 atggcagaaa atgcaacgtt aatagcagca ggaggagacc caaaatatgt gtttacaata
    31441 ggtttttact atggtttctt gcaagtaact ggttcaggga taactttggg attagtgtac
    31501 cttatgtcaa gaagtaagtg taagagtttt aatagtatgg gaaaagttgt gattttacca
    31561 tcactatttg gaataaatga gccggtaata tttggaacac caatagttat gaacccatat
    31621 atgtttgtac catttgtatt tggacctgta ttggttggag cacttaattt tatggcatta
    31681 aaagtaggat tagtaggatt acctattgca gaaccaccag gctttttacc tccaggggtt
    31741 gcagcatttt tgatgacatt agattggaag gcaatcgtat tagtatttgc aagtataata
    31801 cttatgacct tgatatatta tccattcttt aagataatgg agaaggaaga attaaataaa
    31861 aatgcagaat tagctacaac attagatgat gatagctttg atttttaaca agtcattaga
    31921 aggagaagga tatggtacct gaaatggaag aaaaagtatt tagtataata tcagaagcag
    31981 gagatgctaa aagtgatgta atgatgtctc ttaaggaaat aaaaaaaggt gactacaata
    32041 aagcaaaaca ccttttaaat tcagcctcag agaaaataca aacagcatca aagcatcatt
    32101 tagaattact atcaaatgct atgaatagtg aagatagtgg gactgatttt ttagttgtgc
    32161 actctgaaga ccattattca aatgcattat ttgctcattc tttagtatct gaacttgtag
    32221 atatatttga gatgatggac ccaagaatta ataagaatta aatttcttgt aaatagtgct
    32281 tgaagtttgg ctatagttta ttaaatcaat agatttaata aatgaactcc cttttacttt
    32341 aaagtactag tatttataaa tttatttata aatacagtaa atttttaaat agaaaaggag
    32401 atattattat ggaaaaattt tcagtagtaa tagctggagg aggaagtaca tataccccag
    32461 aaatcatatt aatgttgcta gataacttag ataggttacc attaagagca atcaaattat
    32521 atgataatga tgaagaaaga caaaataagg tagctaaagc ttgtgaaata ctaataaagg
    32581 aaaaggaccc taatatagag tatttagcaa caacatgccc taaagaggct tatacagatg
    32641 tagatttttg tttagctcat ataagagttg gaaaacttga aatgagagaa ctagatgaaa
    32701 agatacctct aaaacatggg gtagttggtc aagaaacttg tggaccaggt ggaatagctt
    32761 atggaatgag gtctatagaa ggtgttcttg aaaacataga ttatatggaa aagtattctc
    32821 caaattgttg gatgttaaat tattctaatc cagcatcaat aatagcggaa gctgttagaa
    32881 ggttgagacc taattctagg gtaataaata tttgtgatat gccaataggt atggaacata
    32941 atatagcaag gattgcagga ctcaaatctc gtaaacatat ggatataaga tactttggat
    33001 taaaccactt tggttggtat acttcaatta aagataaaaa aggaaatgaa cttttaccaa
    33061 aattagtaga acatataaaa gaatatggtt ttataaatgg tgaagaagga atgaaaaatg
    33121 acaagaaaga tagttggttt gaaactaatt tatttactaa agaaatagta aaaacagatt
    33181 taactacaat accaagtagt tacttaaagt actatctatt tccagattat gttgtaaatc
    33241 attctgatgt aaattatact cgtgccaatg aagttattga tggaagagaa aaagaagttt
    33301 ttggttcatg tgcattgata gaaaagcaag gacattctaa gggcagtggg cttaagatag
    33361 gaatacatgc agagtttata gtggatttag ctacagctct agcttttaat acacaggagc
    33421 gtatgttatt gatagttcaa aataatggag ctatagaaaa tatacaagat gatgctatgg
    33481 ttgaaattcc atgtatagtt ggaaaagacg ggtatgaacc attatcaata gggaaaatac
    33541 caacattcca aaaaggttta atagaacaac aattagcagt tgaaaaatta gtagttgatg
    33601 cttggattga gaagtcttat aataaattgt ggcaagcact tatgctatct aagacagttc
    33661 ctagtgcaac agttgcaaaa gaattactag atgatttaat agaagcaaat aaaaattatt
    33721 ggccaaaact taattaagaa taatatattt ttaaagttcc tacagtttag tacatagcct
    33781 agttaatgta tttgtaggga ctttatttat ttacaaatga gatacaagtg gcaaacatag
    33841 tgtattttgc agttaggaaa gtaggtttag ttacttgtta gttggattaa atttaggtac
    33901 aataatttac tatcaatcaa tagaaataac cagagaagtt gcataataaa aaatttacac
    33961 ttttaacagg atttatgtag gtgtttatag aaataaataa atatgtacat aaatacataa
    34021 ttatttttaa gtctaaaata caagaatgga gagatggcta tgaagtggag agattatgct
    34081 gatgatgtaa atttatttga ggattttgat aaaactatca agcctctaac tgacgaacaa
    34141 agaagaaaaa atataaacac tttaattgca tatttttcaa aagaagttcc ttctaaaata
    34201 tacaatttat caaatgatga aattaagcct agagatatac ttagaggact tttgaatgta
    34261 tatccaccaa aagaaattgc tccagagata cttaatatgt tacataattt attgttgatt
    34321 gaatgtgaag aaagagagtt agtagatgta aatgatatag aagaaataga ggaagggatt
    34381 gccatatgga gaggtaatat aacgaattta agagcagatg caatagtaaa tgctgcaaat
    34441 aacaagttat tagggtgttt acaaccatta catctatgcg tggataatga gatacattca
    34501 tgcgcaggtc ctagacttag agaagattgt gacaaaataa taaaaaaaca agggcattta
    34561 gaatatactg gagatgctaa gataactaga ggttattgtt tacctgcaaa atttgtagta
    34621 catactgttg gacctattgt atctggtggt cagccaagta aagagcaaga aaagcaactg
    34681 cttcattgtt ataaatcatg tttaaataca ataaaagaaa ttgatgaaat aaaaaatatt
    34741 gttttttgtg gaatttctac aggtgtattt ggttatccaa aaaaagaggc agctaatctt
    34801 gctgtaagta gagttagact atggctaaaa gaaaatcctg aaaaaaattt aaaagttgta
    34861 tttaatgtgt ttactgaaga agaagaagag aaatatagaa gaatatttaa ataatattat
    34921 gtaacagaat cctaaaaata cttattatat aatacaaatt cattgtataa gataataatt
    34981 tacaagtagt aaaaattaat aaaatataat ttgtattt
//
LOCUS       DAYAOO010000038        34257 bp    DNA     linear   BCT 12-OCT-2024
DEFINITION  TPA_asm: Clostridioides difficile isolate ST8-SSI-h139-18
            SAMN40601845-rid21577343.denovo.038, whole genome shotgun sequence.
ACCESSION   DAYAOO010000038 DAYAOO010000000
VERSION     DAYAOO010000038.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN40601845
            Sequence Read Archive: SRR28438827
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 34257)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 34257)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-MAY-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-MAY-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002157583.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002157583.1
            Genome Coverage       :: 163x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/11/2024 16:19:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 4,038
            CDSs (total)                      :: 3,963
            Genes (coding)                    :: 3,930
            CDSs (with protein)               :: 3,930
            Genes (RNA)                       :: 75
            rRNAs                             :: 6, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 60
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 33
            CDSs (without protein)            :: 33
            Pseudo Genes (ambiguous residues) :: 0 of 33
            Pseudo Genes (frameshifted)       :: 7 of 33
            Pseudo Genes (incomplete)         :: 25 of 33
            Pseudo Genes (internal stop)      :: 11 of 33
            Pseudo Genes (multiple problems)  :: 8 of 33
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..34257
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN40601845-rid21577343.denovo.038"
                     /isolate="ST8-SSI-h139-18"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Denmark"
                     /collection_date="2018"
                     /collected_by="Statens Serum Institute"
     gene            302..1777
                     /locus_tag="ACGI5H_002063"
     CDS             302..1777
                     /locus_tag="ACGI5H_002063"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895922.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminotransferase class V-fold PLP-dependent
                     enzyme"
                     /protein_id="HFG9697766.1"
                     /translation="MDSEFANAVELSYECAPLLESLKEYSEKDIACFDVPGHVKNRGV
                     AILNKYLGESLMKMDINSSPTMDNVSAPNGIIKNAQDLLAQAYMADEAFFITNGTTQA
                     IHAMILSVIKPGEKVLLPRNIHKSVINALILCGGIPIFIQPEFDEKLGISLNITLEKV
                     RTEIEKDCNIKALFFLNPTYYGVCADLESIIELCHKNNVLVLVDEAHGAHFPFHLDLP
                     PSAISLGADMVAVSIHKTGGALTQSSALLLNRDNVSFEKVLQSINMLQSTSASYLLMA
                     SIDGARVNLVENGEKQLSKALNLSRYAKSKLNKIDGIKVLSTEILKQKGVKFIDETKL
                     CINVKELNLTGFEVYDLLYKNFSIQVELGDSYNILALVSIGTNKSDIDRLVKALSIIA
                     KIYRKESTLNEFNMVQINPIIKLNPREAFYAPKESVEINSCIDRICGESIMAYPPGIP
                     IIAPGELITEEIMEYIIFLKNSNAYLTDVQDKNLDRILVIK"
     gene            1864..2277
                     /gene="speD"
                     /locus_tag="ACGI5H_002064"
     CDS             1864..2277
                     /gene="speD"
                     /locus_tag="ACGI5H_002064"
                     /EC_number="4.1.1.50"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418655.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004014 - adenosylmethionine decarboxylase
                     activity [Evidence IEA];
                     GO_process: GO:0008295 - spermidine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="adenosylmethionine decarboxylase"
                     /protein_id="HFG9697767.1"
                     /translation="MKFETLGRHILVEYYNCDENVLKDPRLIENFMNDSALNAKATIV
                     DSVFHHFNPWGVSGAVIIAESHLTIHTWPEYGYAAADFFTCGDIDPWKSFELLEQLLK
                     SERSESTEIPRGLTTKIKKYSKKDLGKITHKPEAV"
     gene            2307..3158
                     /gene="speE"
                     /locus_tag="ACGI5H_002065"
     CDS             2307..3158
                     /gene="speE"
                     /locus_tag="ACGI5H_002065"
                     /EC_number="2.5.1.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437154.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polyamine aminopropyltransferase"
                     /protein_id="HFG9697768.1"
                     /translation="MELWYTEEWTENVRFSIKVNKHLFEGKSQFQRIDVFDSDEFGKF
                     LTIDGLMMVTYKDEFIYHEMITHVPMATNLNIKKVLVIGGGDGGTVRELSRYPQIEKI
                     DMVEIDKMVVDVSKEYMDICSCKLDDKRVSLYFEDGVNFVKCAHDKSYDLIIVDSTDP
                     IGPGEGLFSTDFYKDCYRILTDDGILVNQSESPYFDFNAKEMKRANKKLKQIFPISEV
                     YQAHIPTYPSGHWLFGFASKKLNPVKNQDRNGWEKLSLKTKYYNSDIHLGSFMLPQYV
                     KEMLDEE"
     gene            3148..4026
                     /gene="speB"
                     /locus_tag="ACGI5H_002066"
     CDS             3148..4026
                     /gene="speB"
                     /locus_tag="ACGI5H_002066"
                     /EC_number="3.5.3.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888724.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008783 - agmatinase activity [Evidence
                     IEA];
                     GO_process: GO:0008295 - spermidine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="agmatinase"
                     /protein_id="HFG9697769.1"
                     /translation="MKNNFYHMNTFMSMDKNYEESNLIVFGVGFDGTTSNRPGARFAS
                     SSMRKEFYGLETYSPFLDLDLEDYNICDYGDLEISVGSTEQVLKEIYQETYKIVRDSK
                     VPFMIGGEHLVTLPAFKAVHEKYNDIYVIHFDAHTDLREEYNNSKNSHATVIKRIWDI
                     VGDNKIFQFGIRSGTKEEFKFATEEKHTYMEIGGIDTFENIVNMLNGKNIYLTIDLDV
                     LDASVFPGTGTPEPGGVNYREFQEIFKIIKNSNINIVGCDIVELSPDYDTTGVSTVIA
                     CKILRELCLIISDKIK"
     gene            complement(4206..4406)
                     /locus_tag="ACGI5H_002067"
     CDS             complement(4206..4406)
                     /locus_tag="ACGI5H_002067"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003230776.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005829 - cytosol [Evidence IEA];
                     GO_function: GO:0001072 - transcription antitermination
                     factor activity, RNA binding [Evidence IEA];
                     GO_function: GO:0003676 - nucleic acid binding [Evidence
                     IEA];
                     GO_function: GO:0003723 - RNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cold-shock protein"
                     /protein_id="HFG9697770.1"
                     /translation="MKNGIVKWFNNEKGFGFISVEGEDDVFVHFSAIQNDGYKTLEEG
                     EKVSFDITQGNRGPQAENVNRI"
     gene            4873..6363
                     /locus_tag="ACGI5H_002068"
     CDS             4873..6363
                     /locus_tag="ACGI5H_002068"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888725.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4Fe-4S dicluster domain-containing protein"
                     /protein_id="HFG9697771.1"
                     /translation="MFQFETQIHKLRHDVLTAIARLGKEDNLTREAMDNIQYEIIKGE
                     KPTYRCCVYKERAIISERVNVSMGLQPGQDKIDLDTMDIEEDEQIIYILEAACDSCPI
                     NEFTVTDICRGCLAHRCKEACKFGAITHVGGMAYINHELCKACGMCKKACQYDAISEV
                     VRPCKSVCPTNALGFDRENMKAMIHEDKCLNCGACMSACPFGAISDKSLIAPVARKLV
                     QKEKMYAVVAPAITGQVEANVTYGQIKNAIKSLGFVDVLEAACGADAVTVHESLEFAE
                     RMEKGEAFMTNSCCPGFVGYIEKTYPNHVGKISSTVSPMIASGRFIKSHEPDAKVVFI
                     GPCTAKKSEAAKKELKGAVDYVLTFEEIMALFEAFDIDLAKCSNEDIDDASIFGRGFG
                     AAGGLTKAIENYLAEKGIGVNFEPVKISGSREIKKTMTMANLGKLEGNFIEGMMCEGG
                     CINGSGKFLSGAKVKATFDRKNSQSTKKSVLANTKIKDFSNINLEK"
     gene            6643..8139
                     /locus_tag="ACGI5H_002069"
     CDS             6643..8139
                     /locus_tag="ACGI5H_002069"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004453549.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4Fe-4S dicluster domain-containing protein"
                     /protein_id="HFG9697772.1"
                     /translation="MFEFETQLKRLKHEVLTAVARLSIEENLTKENIEKIPYEIIKGE
                     KARYRCCVYKEREVVLERAQLALSLTPNSKYGDINPDSVSLDTDEQIIYIVEAACDRC
                     PINEFTVTELCRGCLAHRCKEACKFGAISYINGRAYINHDLCKACGMCKSSCQYDAIS
                     EVVRPCKSVCPTGALDFNRNTMKAMIHEDNCINCGACMSACPFGAISDKSLIAPVAKK
                     LAKKENMYAIVAPAITGQIDSNITYGQLKNAIKSLGFVDMIEASCGADAVTVHESNEL
                     IERIKSGDNYMTNSCCPGFFKYIEKMFPDEKDRISSTVSPMVATGRLVKKIDSDAKVV
                     FIGPCTAKKSEATEKSLKDSVDYVLTFEELMALFEAFNIDLSKCSNEDINDGSIFGRG
                     FGASGGLAKSVQNYIAEKGLSFDFEPIKVSGPRQIKKTMTMAKLGRLEGNFIEGMMCE
                     EGCINGAGKFLSGVKAKNTFDRKNGQSTKKSVLSNDKIKEFEDVNLER"
     gene            8273..9199
                     /locus_tag="ACGI5H_002070"
     CDS             8273..9199
                     /locus_tag="ACGI5H_002070"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437142.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HFG9697773.1"
                     /translation="MRKIVLKDILFLVTTLSIIVILLLVTNITTNSKIKSTSESYLKS
                     DKNSVRQNGIQRSTKSSTKNTAFKTTILNTGKSDCILVEIGNKVIMIDTGEDKNGKQI
                     VDRLKEKGINTLDYLILTHLDKDHIGGVDSVLSSVKVKNIIQANYKKDSKQYDEYIDS
                     LKKADIEPVLLKDNMNIVINGAEINIHPASKSKYESSNDYSIITNISYGAHKFLFAGD
                     AEEERLSEFINGNTLKYDFVKMPHHGRYDKLTETFLESISPQYAVITCSEKKEPEEGV
                     LKILERLNIKTFLTSNGEVVINSDGKTLSVNQ"
     gene            9317..9508
                     /locus_tag="ACGI5H_002071"
     CDS             9317..9508
                     /locus_tag="ACGI5H_002071"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9697774.1"
                     /translation="MLDRFFGEGGFGGCAWWIIILFFLFLAFQDCWAEMDLCAWIPFL
                     ILLLILCECGDVFDGGCGC"
     gene            9731..10081
                     /locus_tag="ACGI5H_002072"
     CDS             9731..10081
                     /locus_tag="ACGI5H_002072"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888730.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF6483 family protein"
                     /protein_id="HFG9697775.1"
                     /translation="MAIVDKIFNEIKLMVARLLLGKKYSEYEEKDLVYNTEEEVILIT
                     LKRLVFQGNVNEAEEILFDKAKSVNSENMQYIAIEFYTMLMEKTDEELEAMNFSKQEV
                     YQGIEDIRKVLNLE"
     gene            10342..11847
                     /locus_tag="ACGI5H_002073"
     CDS             10342..11847
                     /locus_tag="ACGI5H_002073"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004453547.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1846 domain-containing protein"
                     /protein_id="HFG9697776.1"
                     /translation="MKVGFDHKKYLEEQSKYILERVNNFDKLYLEFGGKLMGDLHAKR
                     VLPGFDENAKIKVLQHMKEKVEVVICVYAGDIERNKIRGDFGITYDMEVLRLIDDLRG
                     YELDVNSVVITRFEGQPATTVFINKLERRGIKVYKHYPTKGYPSDVETIVSDEGYGAN
                     EYIETTKPIVVVTAPGPNSGKLGTCLSQLYHENKRGNVVGYSKFETFPVWNVPVKHPL
                     NIAYEAATVDLKDVNMIDSFHLETYGEMSVNYNRDLELFPVLKKIIEKITGKESIFQS
                     PTDMGVNRVGFGIIDDEVIRKASIEEIIRRYFKTACEYKKGQVDKGAYDRMKMIMEEL
                     NLKPEDRNVVLPARNYSNKLKESADKNDTCPVVALELEDGTILTGKGSDLMNGTAAVV
                     LNAIKHLANISDDMHLISPVILEPIINLKTKTLASRNVSLSCQEVLTALSICAVTNPT
                     AQFAMEKLALLKGCQAHSTTILNRDDEQTFRKLGIDVTCDPEYPSQNLYYS"
     gene            12237..13334
                     /gene="dinB"
                     /locus_tag="ACGI5H_002074"
     CDS             12237..13334
                     /gene="dinB"
                     /locus_tag="ACGI5H_002074"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728707.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003684 - damaged DNA binding [Evidence
                     IEA];
                     GO_function: GO:0003887 - DNA-directed DNA polymerase
                     activity [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase IV"
                     /protein_id="HFG9697777.1"
                     /translation="MKHYRKIIHIDMDAFYASIEQRDNKKLKGRPVIVGGNPQSRGVV
                     ATCSYEARKFGIHSAMPSAVAYNRCPYAVFVRPRFDVYKSVSEQIRDIFYRYTDLVEP
                     LSLDEAYLDVTKNKKNIDSSIEIAKQIKKDIFREVGLTSSAGVSYNKFLAKIASDLRK
                     PNGLTVITEENAQDFLDKLPVNKFFGVGKVTSNTLKNLGIKTGYDLRCLNLFELENIF
                     KKRGYELYKFARGIDDRPVEPNRVRKSVGAETTLSHNLDIDEEETRNILDELCEEVCH
                     RLKNSEKFGKTLTLKIKYEDFTKITRSLSLEHYIDEYNDIRSGVDNLLRNVEVNGKQI
                     RLLGVTISNLSDKKETYKDITLFEYMDSIQM"
     gene            13597..14733
                     /locus_tag="ACGI5H_002075"
     CDS             13597..14733
                     /locus_tag="ACGI5H_002075"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437132.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HFG9697778.1"
                     /translation="MIEIRNVTKKIGNNVILDDISLVVETGTLVVLIGSSGCGKTTTL
                     KLINKLIKPTSGEIYINGKPISQENEIELRRKIGYVIQNTGLFPHLTIKENIELIPRL
                     KKEKSVEEIEKRTLQLLEMVGLDSDEFLNKYPSELSGGQQQRIGVARAIATDAEIILM
                     DEPFSALDPITRTSLQEQLFSLQDELKKTIIFVTHDMDEALKIADKICIMKDGRIAQY
                     DTPENILRKPANDFVKDFIGEDRVWDNPEYIKARDIMIKNPIAVNSTRTVTQGIEIMR
                     TSKVDSLLIIDRAKTLKGIVTVKDMKDIDDKSILLADIMSSEPLHVNEGDNLVEILNV
                     MNRNSVGYIPVISDENKLVGLITRSSLLSVLSEQFLEMEVSVLG"
     gene            14726..16273
                     /locus_tag="ACGI5H_002076"
     CDS             14726..16273
                     /locus_tag="ACGI5H_002076"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895932.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0043190 - ATP-binding cassette (ABC)
                     transporter complex [Evidence IEA];
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycine betaine ABC transporter
                     substrate-binding protein"
                     /protein_id="HFG9697779.1"
                     /translation="MANFFNFILLQKDKIIELLIQHMSLTVTSILIAIIVGVPLGIII
                     SRISSLRKFVLGFVNLVQAVPSMALLGLLVPILGIGSKPAIFMVVVYSLLPIVKNTYI
                     GITSIDPVVLESAKGIGLTRNQTLFKIQFPLALPIIMGGVRISAVTAVGLMTLAAFIG
                     AGGLGYLVFSGVQTVNNNMILAGAIPSCIIALLVDYLFSKIEVAVTPKGLNPKAPKKN
                     YIALKVISVVVVVSMLFVVFSSSFSSKKDTITIGSKDYTEQLILGNVYAELVEKNTNL
                     KVKKNLNLGGSSVAFNAIKSGELDMYVDYTGTLLVNVMKHAPIKDADEAYNVVKDTME
                     KENQLTLLDPLGFNNTYTLAMMPETAEKYGINTISDLTKYGKEFTFSPTLEFENREDG
                     LVGLSRDYGLKFKDVKAMNGSLRYTALDNNESQVIDAFLTDGLIKKFNLKILEDDKNF
                     FVPYYAAPLVREDTLKKYPELEKVMNMLSGKINEETMRELNYQVDELGKSPEEVAHSF
                     LVKEGLV"
     gene            16608..17474
                     /locus_tag="ACGI5H_002077"
     CDS             16608..17474
                     /locus_tag="ACGI5H_002077"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004453540.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008324 - monoatomic cation transmembrane
                     transporter activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cation diffusion facilitator family transporter"
                     /protein_id="HFG9697780.1"
                     /translation="MDNYKKVKQVLWIILFANFAVALLKIIIGNQIKSYSMTADGFHS
                     LSDGASNIVGLIGIFFASKPKDKNHPYGHKKFEIITSLFISGMLFVIAIKIILSAVLR
                     IANPVVPAITIESLIALIITLFINIFVCMYEYRIGTKLNSYVLISDSLHTRSDIFVSL
                     GVLVTLVGVKLGFPVIIESIVPIIISAFIIYSAYGIFRPSIGILVDRVAVDEDYIKEI
                     VFEFNEVRDVHNIRSRGSKSSIYIDMHVMVDPFISVEQSHDLTHKIEKQIQEEINENA
                     QVIVHIEPFYSF"
     gene            17615..18757
                     /locus_tag="ACGI5H_002078"
     CDS             17615..18757
                     /locus_tag="ACGI5H_002078"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437122.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldo/keto reductase"
                     /protein_id="HFG9697781.1"
                     /translation="MRYVEYGKTGKMVSVVGYGGLRFDLEKSNQENADLVKYAYEKGI
                     NYFDTAPGYCDDRSEDIFGLAFRQMIKEGKTDFYVSTKEKPKACDTSEKAIEAVKKSI
                     ERLGVSKINFYHVWNIRKMEHYELAMRPGGQYEGLLKCKEEGLIDHIVFSSHQPGDEV
                     IDILSENKFEGVTMGINILNFPYRLKGAKYAVDNGYGVVAMNPLSGGTIPKYNKELSF
                     LSKDGESTIESALRFNIGISQISISLIGFNKKQDIDDACKIADENRIYSDEDIHDIET
                     RLNKNMNEICTGCGYCKVCPKGINTPAYMLFYNEKQMFKKSDEEMTKLVYGLGHWNYT
                     MNSKAKAKECISCGKCEVECTQHLPIIDRLKEIKKWEEDGANSVKV"
     gene            19159..20379
                     /locus_tag="ACGI5H_002079"
     CDS             19159..20379
                     /locus_tag="ACGI5H_002079"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418682.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF6080 domain-containing protein"
                     /protein_id="HFG9697782.1"
                     /translation="MSKILKYKNEMFLFILVVITYLIITKIFFSKTTIFYDLNNTYDV
                     LLDTDTGVLFNLNVFAISQDNSKHILFSAIISIFAYPIYLFCTSIANPGTTDFNSAYG
                     FGLICLQIITSAMSITLVFNHIKKIKMQRLTLILLTMIMIFSFPQLFMTLNVERFIYS
                     QFSLIFFIVIANKMKGKNSYLVELAAIPLFGITISNIYLYFFNMIFEFKLKIGKMLKH
                     LITFILMAYICVVSTKSYESFMNLGNVIQYDTKFISGEPILEKIAMIIERLLYSVFYF
                     PGASIKKGLFLQNGEVATIPVILTLLALCFCVLSVIENSEKRVPKLCMGIIIFNLTLH
                     GIVGYNLVNSSIMAINFSFAVIILLAYFTKALRKNEKNMYNIFLSLLLVTIVISNVNG
                     FIEILNIGIKSYPV"
     gene            20408..21295
                     /locus_tag="ACGI5H_002080"
     CDS             20408..21295
                     /locus_tag="ACGI5H_002080"
                     /EC_number="2.4.2.45"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861057.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016765 - transferase activity,
                     transferring alkyl or aryl (other than methyl) groups
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="decaprenyl-phosphate phosphoribosyltransferase"
                     /protein_id="HFG9697783.1"
                     /translation="MKQTNTSIRLLTKISDYIKLMRIKQYIKNFFVFSAIIFSNNILN
                     INLFLNTFIAFVCFCLMSSSVYALNDAIDMDKDKKHPKKCNRPVASGRISKKSANILF
                     VVLALISVCLSTVVSFNLSIILSLYLINNILYSLKLKNIILLDVFSISLGFILRVYAG
                     CVAISVSLSNWIILCTFFLSLYLALGKRKKEIETLRDDAVEHRKILEDYDIENLNQMM
                     IVILSSTIVCYALYSTSNPEKPHMIFTTIFVVYGVLRYNYIINTTNENNPTDIVLKDN
                     ALKINVILWIITCLIILIF"
     gene            21329..21958
                     /locus_tag="ACGI5H_002081"
     CDS             21329..21958
                     /locus_tag="ACGI5H_002081"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895936.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA];
                     GO_process: GO:0008152 - metabolic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="HAD-IB family hydrolase"
                     /protein_id="HFG9697784.1"
                     /translation="MKKSVLLLDVDYTVINTDSMIDFFIYSLKNKTFKTIIKLPYIIF
                     ILFMYLIRMIPLKKAKEAIFYPIVDFSEEDLKKFFDDCIMKKINESMKKVIYKNKEED
                     NVIIMITASPYAYMKYFKYYGLADEVIGTEFFYENSRYKNQFIGENCKGIEKVKRIKA
                     VLGKLGIEIDYENSYAYSDSKSDLPMLSLTKNAFLVSKKDGEVIEQINS"
     gene            21990..22427
                     /locus_tag="ACGI5H_002082"
     CDS             21990..22427
                     /locus_tag="ACGI5H_002082"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728704.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="COG2426 family protein"
                     /protein_id="HFG9697785.1"
                     /translation="MGYLHILILSMVPVTELRGAIPIGIAMGLNPIWVYVFSVIGSTL
                     VSIPLILTFRHVLQFLRGKKLFKGIADVIDRKINSRMKKLKSVSIIGIILFVGIPLPT
                     TGTWTASAIASILKMRIKDAFMGVFLGNLLSGVIVSALSLHII"
     gene            22677..24044
                     /locus_tag="ACGI5H_002083"
     CDS             22677..24044
                     /locus_tag="ACGI5H_002083"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437109.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0042910 - xenobiotic transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0006855 - xenobiotic transmembrane
                     transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MATE family efflux transporter"
                     /protein_id="HFG9697786.1"
                     /translation="MENSNTNLGSESVGKLLFKLATPAIIAQIVNVLYNIVDRIFIGR
                     MENGEVAMAGVGVAFPIIIIITACSYLIGMGGGPLAAIKMGEQNNDEAEKIMSNSFSV
                     LVILAILLTIGFKIGKEPLLWMFGASESTIGYSMDYLNIYLIGTVFVQISMGMNTFIN
                     TQGFATTGMMTVAIGALINIILDPIFIFGFNMGVKGAALATIIAQGVSAIWVLMFLFG
                     KKSILKIKKKYMIPKASIILPVLGLGISPFIMQSTESLVLIALNSKLQMYGGDLAVGS
                     MAIMSSIMQILMLPNMGVTQGAQPIISYNYGSGQLDRVKKTFKLCLLSCFTYSTILWL
                     LLMIFPAFFVSIFNKNPQLLSMTSWSIKIYFAGAFMFGIQIACQQTFLALGKATISLV
                     LALLRKIVLLIPLIFILPTFFNEKLFAVILAEPVADITAATITAISFFIFYKCFLSKP
                     KAIKE"
     gene            24244..25518
                     /locus_tag="ACGI5H_002084"
     CDS             24244..25518
                     /locus_tag="ACGI5H_002084"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418693.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003676 - nucleic acid binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="S1 RNA-binding domain-containing protein"
                     /protein_id="HFG9697787.1"
                     /translation="MFIMENDLTMQELLDQQEQVFSKVKVGELTTGKITAVRNDEVQL
                     GLDYGFDGIIPISELNIEKNQYIEDIYHIGDEITAVITKVSQKDGTITLSKLQLDKRN
                     DFAELQKAYDEHRIITVNVEKNIDKGVFANYNTYTFFIPISQLDTKFITDTSKFVGLN
                     LEVYIKELDVRKNRLVASHRDVLQERINKEREERRAQIKAEKEAERARIKQEREEEKA
                     RIKAAKEDLFNSLEVGQKRDGKVTKIMPYGAFVDIGGIEGLAHINNLAWTRVESVEDV
                     VSEGQEVEVYVLDVNKETKKIALALKDINNDPWDLIAKEVQIDDVVNVKVLRIIEKGA
                     FVQIKEGVDAYLPISELSDTRVAKVTNVVNIGDEVKVKILDFKPKTKRMLVSIKEATR
                     EPEEDITEYLEVEESLGSIGELFKDKFKDLEV"
     gene            25636..26355
                     /locus_tag="ACGI5H_002085"
     CDS             25636..26355
                     /locus_tag="ACGI5H_002085"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895939.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatase"
                     /protein_id="HFG9697788.1"
                     /translation="MKKSIMDVHCHTLISGHAHSTFKENVEEASKKNIKYLGISDHGP
                     NMPGGPHPFYFYNLHLLPREVQGVKILRGIEGNIMDYNGNLDVQEDMLQHLDYIIASL
                     HRPCIASGTKEENTNAILKVMDKPKVKIIGHPDDSRYPLDYEPIVKKAKDKNILLEIN
                     NSSLSSNSHRTGTWENVSHMLTLCKTYGARVILGTDSHICYSIGEFENAEKVLEAVDF
                     PDELVINYHEDEIIEFFDINF"
     gene            26376..26822
                     /locus_tag="ACGI5H_002086"
     CDS             26376..26822
                     /locus_tag="ACGI5H_002086"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861059.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9697789.1"
                     /translation="MSKNKFIYMNYYDNGYFKKGMTIYMVLALIILATIFIYSTTILY
                     ILCIITAVFLFKQGRDFSNKYEGKVYITLDNHSILINNQCIFSIKSKQSQKFNYKIIE
                     KIEVVKNILNIYTDESNYKIRLRALSLEDEKKLLNIIDEKMKKFKA"
     misc_binding    26970..27216
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            27340..29082
                     /gene="leuA"
                     /locus_tag="ACGI5H_002087"
     CDS             27340..29082
                     /gene="leuA"
                     /locus_tag="ACGI5H_002087"
                     /EC_number="2.3.3.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003852 - 2-isopropylmalate synthase
                     activity [Evidence IEA];
                     GO_process: GO:0009098 - L-leucine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="2-isopropylmalate synthase"
                     /protein_id="HFG9697790.1"
                     /translation="MKCGKYKKYDKMQIVNRKWPDNEIFKAPIWCSVDLRDGNQSLPT
                     PMSVNEKVRMFKMLIDTGFKEIEVGFPSASNTEYTFLRKLIDENMIPDDVTIQVLTQS
                     RAHLIEKTFESIRGCKKAIIHLYNSTSVLQRDVVFNMSKQEIIDIAVEGAKLFNEEVK
                     KYPETEFTFEYSPESFTGTEMDYALEICEAVIDVWKPTTQKKVIINLPSTVEMATPNV
                     YADQIEWFCKNISCRDSIILSLHTHNDRGTCTAASELGLLAGADRLEGTLFGNGERTG
                     NMDIVNVGLNLYTQGIDPELDFSNIDKIIGIYEDCTKLMVHDRHPYAGNLVHCAFSGS
                     HQDAIRKGMIAMKNRDNDYWEVPYLPIDPHDIGREYKEIIRINSQSGKGGAVYIMETD
                     YGFMIPKNMHSDFGNVVKMESDRIGEELSSEAIFNLFKKEYIEVESPYKVKKYKIKSM
                     DELNYENDDSNDTNMIEMTARISYMGNEQRIVGIGNGPVDSFNNALKQCGMKDYKFRY
                     YWEHALEEGSHSRGVAYVGIEHNNEVYFGVSISENINTAAINALMNAINKSYIEEEIK
                     NGDDYDAENISQTC"
     gene            29039..30316
                     /gene="leuC"
                     /locus_tag="ACGI5H_002088"
     CDS             29039..30316
                     /gene="leuC"
                     /locus_tag="ACGI5H_002088"
                     /EC_number="4.2.1.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418697.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009316 - 3-isopropylmalate dehydratase
                     complex [Evidence IEA];
                     GO_function: GO:0003861 - 3-isopropylmalate dehydratase
                     activity [Evidence IEA];
                     GO_function: GO:0051539 - 4 iron, 4 sulfur cluster binding
                     [Evidence IEA];
                     GO_process: GO:0009098 - L-leucine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="3-isopropylmalate dehydratase large subunit"
                     /protein_id="HFG9697791.1"
                     /translation="MGMTMTQKILAKHAKLNEVKKGQLIEADLDVVLGNDITSPVAIR
                     EFEKLGIEDVYDKTKVVMVLDHFTPNKDIKSAEQCKFTRSFAKSKGVVNFFDVGDMGI
                     EHVLLPEKGIVTAGDVIIGADSHTCTYGALGAFSTGVGSTDMGAGMATGKCWFKVPGA
                     IKFVLKNKPNKWISGKDIILHIIGEIGVDGALYKSMEFCGDGVEYLSMDDRFTICNMA
                     IEAGAKNGIFPVDDKTMEYINSHKCSTMTKDVNIYEADEDAVYDEVYEIDLAELKETV
                     AFPHLPENTRTVDEIDKDIKIDQVVIGSCTNGRISDLEVVAEIMKGKKVADGVRVMIF
                     PGTQKVYLEAIEKGYITTFIEAGAAVSTPTCGPCLGGHMGILAAGEKSISTTNRNFVG
                     RMGHVDSEVYLASPAVAAASAITGKISKPSEII"
     gene            30331..30822
                     /gene="leuD"
                     /locus_tag="ACGI5H_002089"
     CDS             30331..30822
                     /gene="leuD"
                     /locus_tag="ACGI5H_002089"
                     /EC_number="4.2.1.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004453523.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009316 - 3-isopropylmalate dehydratase
                     complex [Evidence IEA];
                     GO_function: GO:0003861 - 3-isopropylmalate dehydratase
                     activity [Evidence IEA];
                     GO_function: GO:0016836 - hydro-lyase activity [Evidence
                     IEA];
                     GO_process: GO:0009098 - L-leucine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="3-isopropylmalate dehydratase small subunit"
                     /protein_id="HFG9697792.1"
                     /translation="MIANGSVFKFGDNIDTDVIIPARYLNIADYKELATHCMEDIDDK
                     FISKVKKGDIIVATKNFGCGSSREHAPIVIKESGVSCVIASTFARIFFRNSINIGLPI
                     LECEEAANNIDEGDNIEVDFSTGVIKNITKGKEYKAEPFPEFMQNIILNEGLINSIKA
                     NRG"
     gene            30829..31899
                     /gene="leuB"
                     /locus_tag="ACGI5H_002090"
     CDS             30829..31899
                     /gene="leuB"
                     /locus_tag="ACGI5H_002090"
                     /EC_number="1.1.1.85"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895944.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003862 - 3-isopropylmalate dehydrogenase
                     activity [Evidence IEA];
                     GO_process: GO:0009098 - L-leucine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="3-isopropylmalate dehydrogenase"
                     /protein_id="HFG9697793.1"
                     /translation="MNCNIAVIKGDGVGPEIIDEGIKVLNKICCKFNHRFDCEYVLAG
                     GCAIDETGEPLPNKTVETCRKNEAVLLGAVGGPKWDKCKGDKRPESGLLKLRESLGLF
                     ANLRPATMYESIKEASPLRTDIVEKGIDFVVVRELTGGIYFGERGRKIIDGIENAYDV
                     EIYNENEIRRIGKRAFEIARNRNKKLISVDKANVLESSRLWRSIMEDLAKEFEDVELS
                     HMYVDNAAMQVVKDPSQFDVIVTNNIFGDIISDEASMITGSIGMLPSASLREDSFGMY
                     EPIHGSAPDIAGKDIVNPIATILSVSMMLRHSFNLEEEAKCIEDAVQSVLNKGYRTID
                     IYNGVGNVVGTREMGELIVNEI"
     gene            32262..32777
                     /locus_tag="ACGI5H_002091"
     CDS             32262..32777
                     /locus_tag="ACGI5H_002091"
                     /EC_number="3.1.2.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437086.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016790 - thiolester hydrolase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PaaI family thioesterase"
                     /protein_id="HFG9697794.1"
                     /translation="MDFLAKYKVLKKQNSSKSCLVCGTQNELGLKADFYELENGELVS
                     ICNTKDWHQSYPGRVHGGMSAAILDETIGRAVSINDDQIWGVTVSLELKYKKPVPTDA
                     TIKVVGRITKENRKLFEGTGEIILPNGDIAVTATGKYMKMPIGQIAEGDFSNEEWFFE
                     ESKEKVEYIEL"
     gene            33150..34226
                     /locus_tag="ACGI5H_002092"
     CDS             33150..34226
                     /locus_tag="ACGI5H_002092"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004453520.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alanine--glyoxylate aminotransferase family
                     protein"
                     /protein_id="HFG9697795.1"
                     /translation="MSKKLFIPGPIDVKEEVLQKMATPMIGHRGKDASMLQKSISEKM
                     QKLFYTNNTILLSTSSGTGLMEGSIRSCTSKKAAVFSCGSFGDRWYKMAVANNVPADI
                     FKVELGEATTPEMVDKVLSTGEYDLITVTHNETSTGIRNPIEEIGEVVKKYEDVIYCV
                     DTVSSAGGIKVEVDKIGIDICITSVQKALGLPPGMSICTFSQKAIDRAKQVPFRGVYL
                     DLLAMYEYLIKKNYQYPSTPSLSHMFALDFQLDNILDEGLDNRFNRHEDMANLVRNWA
                     KKHFQIFTNENHLSNTLTVIENTQGISVSNLNSKLQERGFQIANGYGDLKEKTFRISH
                     MGDYTVEDVQELLDNIDDILGFNK"
BASE COUNT        13413 a         3586 c         6168 g        11090 t
ORIGIN      
        1 aaactcaaaa gcttactaaa actcaaaaaa gtaaaaaaaa caaaataata aaaaataaga
       61 aagtttataa atactaagtt ttaaaaaaat taatataaac aacaaaaaaa taaaaagttt
      121 ataaatattg atatagctaa tgtatatgtt tttgagtaac ttcaaaaaaa cacttgtaaa
      181 aatgctgaga tgttaatata ataaatatca tgagtttaat aaaagtaaaa ataaaaaata
      241 gaaataataa ataataaata ttaaaaatat ttgaatatag agaggagatg aatttgaaat
      301 catggatagc gagtttgcaa atgcagttga attaagctat gagtgtgctc cattattaga
      361 gtcgttaaag gaatactcag agaaagatat agcttgtttt gatgtgcctg gacatgtaaa
      421 aaatagaggt gtagctatat taaataaata tctaggtgaa agtctcatga aaatggatat
      481 aaattcatca ccaactatgg ataatgtatc tgcgccaaat gggattataa aaaatgcaca
      541 agatttgcta gcacaagcat atatggctga tgaggcattc tttataacga atggcacaac
      601 tcaagcaata catgcaatga ttttgagtgt tataaaacca ggtgaaaaag tattacttcc
      661 aagaaatata cataaatcag taataaatgc gttaatactt tgtggaggaa taccaatatt
      721 tatacaacca gaatttgatg aaaaactagg tataagttta aatattactc ttgaaaaagt
      781 tagaacagag atagaaaaag attgtaatat aaaagcatta tttttcctta atccaactta
      841 ctatggagtt tgtgcagacc ttgagagtat tatagaacta tgccataaaa ataatgtttt
      901 agtgttagtt gatgaagctc atggtgcaca ttttccattt catttagatt tacctccttc
      961 tgcaataagt ttgggagctg atatggtagc tgtaagtata cataaaactg gaggagcatt
     1021 gacacaatct tcagcactct tattgaatag agataatgta agttttgaaa aggttcttca
     1081 atcaatcaat atgctacaat caacatcagc atcttatttg cttatggcaa gtatagatgg
     1141 tgctagagtt aatctagttg agaatggtga aaagcaactg tcaaaagcat taaatctatc
     1201 taggtatgca aaatctaaat taaacaaaat tgatggaata aaagttttat ctacagaaat
     1261 attgaaacaa aaaggtgtta aatttataga tgaaacaaaa ttgtgtataa atgtaaaaga
     1321 attaaatttg actggatttg aagtatacga tttattatat aaaaattttt caattcaagt
     1381 agaattggga gattcatata atatactggc acttgtgtcc attggaacaa ataaatcaga
     1441 tatagataga ttagtaaaag cactttctat aattgcaaag atttatagaa aagaatcaac
     1501 attaaatgaa tttaatatgg ttcaaataaa tccaattatt aaacttaatc caagagaagc
     1561 tttttatgca ccaaaggaaa gtgtagaaat caattcatgt atagatagaa tttgtggaga
     1621 atcaataatg gcatatccac caggtatacc gattattgct ccaggagaat tgataacaga
     1681 agaaattatg gagtatatta ttttcttaaa aaatagcaat gcatatctta cagatgtaca
     1741 agataaaaac ttagatagaa tattagtaat aaaataaatt actttatttt gcaagggcaa
     1801 gtatttgtta agtagagttt atcaaataga acttattaaa agtataaagg agttggggtt
     1861 gaaatgaaat ttgaaacact aggaagacat atactagtag aatactataa ttgtgatgaa
     1921 aacgtactta aagacccacg tcttatagaa aattttatga atgattcagc attaaatgca
     1981 aaagcgacaa ttgtggattc tgtattccac cattttaatc cttggggggt ttcaggagct
     2041 gttataattg ctgaatctca tttgacaata catacatggc ctgaatatgg ctatgcagca
     2101 gcagattttt ttacttgtgg tgatatagac ccatggaaaa gttttgaatt attagagcaa
     2161 cttttaaagt ctgaaagaag cgagtctaca gaaattccaa gaggcttaac tacaaaaatt
     2221 aaaaaatatt caaaaaaaga tttaggtaag attactcata aaccagaagc agtataaaac
     2281 atacaagaga aagtgaggat tattatatgg aactttggta tacagaagaa tggacagaaa
     2341 atgtaagatt ttctataaaa gtaaataaac atctatttga aggaaagtct caatttcaaa
     2401 ggatagatgt gtttgatagt gatgaatttg gaaaatttct aacaatagat ggattaatga
     2461 tggtaacata taaagatgaa tttatatacc atgagatgat aactcatgtt cctatggcta
     2521 caaatttaaa cataaagaaa gtattagtca taggtggagg tgatggaggt acagtaagag
     2581 aattaagccg ttatcctcaa atagaaaaga ttgacatggt tgaaatagat aaaatggttg
     2641 tagatgtatc taaggagtat atggatatat gctcatgtaa attagatgat aaaagagtga
     2701 gtttatattt tgaagatggt gttaattttg ttaagtgtgc acatgataaa tcatatgacc
     2761 tgataatagt agattcaact gacccaatag gaccaggtga agggcttttc tcaactgatt
     2821 tttataagga ttgttataga atactgactg atgatggaat tttagtaaat caaagtgaaa
     2881 gtccgtattt tgactttaat gctaaagaga tgaaaagagc taataaaaaa ttaaaacaga
     2941 tatttccaat atcagaagtt tatcaagcac atataccaac atatccatct ggtcactggt
     3001 tgtttggatt tgcttcaaaa aaacttaatc cagtaaaaaa tcaagataga aatggatggg
     3061 agaaattaag tttaaaaact aaatattata atagtgatat acatttaggt tcgtttatgt
     3121 tacctcaata cgtgaaggag atgctagatg aagaataatt tctatcatat gaacactttt
     3181 atgagtatgg acaaaaatta tgaagaatct aatcttatag tatttggtgt tggatttgat
     3241 ggaactactt ctaacagacc tggggctaga tttgcaagta gctctatgag aaaagaattt
     3301 tacggtcttg agacatatag tcctttttta gatttggatt tagaggatta taatatatgt
     3361 gattatggag atttagaaat tagtgttgga agtacagaac aagtcttaaa agaaatctat
     3421 caagagacat ataagattgt tagagattca aaggtaccct ttatgattgg aggagagcat
     3481 ttagttacat taccagcctt taaagcagta catgaaaagt acaatgatat atatgtaatt
     3541 cattttgatg cccatactga tttgagggaa gaatataata atagtaaaaa ttctcatgca
     3601 acagtaatta aaagaatatg ggatattgta ggtgataata aaatatttca atttggtata
     3661 aggtctggga caaaagaaga atttaaattt gctacagaag aaaaacacac atacatggaa
     3721 ataggaggaa tagatacgtt tgaaaatata gttaatatgc taaatggaaa gaatatttat
     3781 ctaactatag atttagatgt attggatgca tctgtgtttc caggaacagg tacaccagaa
     3841 cctggtggtg taaattatag agagtttcaa gagattttta agattataaa aaactctaat
     3901 ataaatatag ttggttgtga cattgtagag ttaagccctg attacgatac aacaggtgta
     3961 tcgacagtta tagcttgtaa aatcttaaga gagttatgct taataatatc tgataaaatt
     4021 aaatagagta ttttatataa atagtatata ttataatata agaagttatt ttaaaaaagt
     4081 tagtttaagt ttgacgcttt tctaaagtaa cttcttattt ttgtaattaa aaataaatat
     4141 aataaacaac aaaaaagagc cctcgatagc tccttttcta aaatatatat atttaaatta
     4201 aataattata ttctatttac gttttcagct tgaggtcctc tattaccttg agttatatca
     4261 aagctaacct tttcgccttc ttctaaagtt ttgtatccat cattttgtat agctgagaaa
     4321 tgtacgaaaa catcatcttc tccctctaca gatatgaacc caaatccttt ttcattgtta
     4381 aaccatttta ctattccgtt tttcattata agaaaacctc cgcattatta aaaaatacaa
     4441 actaaaaaaa taagtctgtt ctattaatat aacataaatt ttaaataaaa gcaaataaaa
     4501 tttttaaaaa aattaattac ttttagaatt taataaaaat tgttaaatta tacagtgaga
     4561 agtattgtaa aatttgacga aaatgtaaat gtagataata aatttaatat caaaaaatgt
     4621 aacaaaaagg tatgtaagta aaaagtaaaa ttaaaatata taataaaaaa tattatatat
     4681 tagattgaaa agtaaaaata aaaatagtga aatttcagaa atatcaataa tattatataa
     4741 taaaacaaaa aaacactata tatattcgat aaaataaaat ttaaacatat aatattttat
     4801 gtatatatta ataaaaggac atattgtgtt ataatggtat cgtataaaat catttacggg
     4861 ggtggtatta aaatgtttca atttgaaaca caaatacaca aattaagaca tgatgtttta
     4921 actgcaatag ctagacttgg aaaagaagat aaccttacca gagaagcaat ggataatatt
     4981 cagtatgaaa taataaaagg tgagaaacct acatacagat gttgtgttta taaagaaaga
     5041 gctataatat ctgagagagt aaatgtaagt atggggttac aaccaggtca agataagata
     5101 gatttagata caatggatat agaagaagat gaacaaatta tatatatttt ggaagctgca
     5161 tgtgacagtt gtccaataaa tgaatttaca gtaacagata tttgtagagg atgtctagca
     5221 catagatgta aagaagcttg taaatttgga gctataacac atgtcggagg aatggcctat
     5281 ataaatcatg aattatgtaa ggcttgtgga atgtgtaaaa aagcttgtca atatgatgcc
     5341 atctcagagg ttgttagacc atgtaagagt gtttgtccaa ctaatgcctt aggatttgat
     5401 agagaaaata tgaaagctat gatacatgag gataaatgtt taaactgtgg agcatgtatg
     5461 tcagcatgtc catttggagc aatatctgat aagagtttga tagctcctgt agctagaaag
     5521 ttagttcaaa aagagaaaat gtatgcggtg gtagctccag ctataacagg tcaagttgaa
     5581 gcaaatgtta catatggtca aataaaaaat gctataaaat cactaggatt tgttgatgta
     5641 ttagaagcag cttgtggagc agatgcagtt acagttcatg aaagcttaga atttgctgaa
     5701 agaatggaaa agggagaagc ttttatgaca aattcttgtt gtccaggatt tgttggttat
     5761 atagaaaaaa catacccaaa tcatgtaggg aaaatatctt ctacagtatc tcctatgata
     5821 gctagtggta gatttataaa aagtcatgaa ccagatgcta aagttgtatt cataggacca
     5881 tgtacagcca aaaagagtga ggcagctaag aaagaattaa aaggagctgt tgattatgta
     5941 cttacttttg aagaaataat ggcattattt gaggcatttg atatagactt ggctaagtgt
     6001 tcaaatgaag atatagatga tgcatcaatt tttggaagag gttttggagc tgctggtggt
     6061 cttacaaaag ctatagaaaa ttatcttgct gaaaaaggta ttggtgttaa ttttgaacct
     6121 gtaaagattt ctggttcaag agaaatcaag aaaactatga ctatggctaa tttaggaaag
     6181 ctagaaggta attttataga aggaatgatg tgtgaaggtg gttgtataaa tggttctggt
     6241 aaattcttat caggtgcaaa ggttaaagcc acttttgata gaaaaaattc tcaatcaact
     6301 aagaaaagtg tcttagcaaa tacaaagata aaagatttta gtaatataaa tttagaaaaa
     6361 taaagataat acaaagcaac aaaaatacat attgttaata gagttgttct aagttgaggt
     6421 ttaacttttg gacaactcta tttttattta tatatttaat tattgaacaa ctaaaataaa
     6481 aattatatac acttaaaata aaaattacat atataatatt ttgtatataa cttaacaaag
     6541 tatatgccta tgttataata atttatagaa ataaataaaa aatacaatat acataatagt
     6601 agaaatatag caaaaaggtg tgatttatag ggaggattac ttatgtttga atttgaaacg
     6661 caactaaaaa ggttaaaaca tgaagtttta acagcagtag caagactatc tattgaagaa
     6721 aatttaacaa aagaaaatat agaaaaaatt ccatatgaaa taattaaagg agaaaaggcg
     6781 agatatagat gttgtgttta taaagagaga gaagtagttc ttgaaagggc gcaacttgca
     6841 ttaagtttaa ctccaaatag taaatatgga gatataaatc cagattcagt tagtttggac
     6901 acagatgagc aaattatata tatagttgaa gcagcatgtg atagatgtcc aataaatgaa
     6961 tttacagtta cagagctttg tagagggtgt ttggctcata gatgtaagga agcatgtaaa
     7021 tttggggcaa tttcttatat aaatgggaga gcatatataa atcatgattt atgtaaggct
     7081 tgtggaatgt gcaaaagttc atgtcaatat gatgctatat cagaagttgt aagaccttgt
     7141 aaaagcgttt gtccaacagg agctttggat tttaatagaa acactatgaa agcaatgata
     7201 catgaagata attgtataaa ttgtggagca tgtatgtcag catgtccttt tggagcaata
     7261 tctgataaga gtttgatagc acctgttgca aaaaaacttg caaagaaaga aaatatgtat
     7321 gcaatagtag ctccagctat aacaggtcaa atagatagta atattacata tggtcagtta
     7381 aaaaatgcta taaaatcact gggatttgta gatatgatag aagcttcttg tggagcagat
     7441 gcagttacag ttcatgaaag caatgaactt attgaaagaa taaaatcagg agataattac
     7501 atgacaaatt catgttgtcc gggatttttt aagtatatag agaagatgtt cccagatgaa
     7561 aaagatagaa tatcatctac agtgtctcct atggtagcaa caggaagatt agtaaaaaaa
     7621 atagattctg atgctaaagt tgtatttata ggtccatgta cagctaaaaa gagtgaggca
     7681 acagagaaaa gtttaaaaga ttcagtagat tatgtactta cttttgaaga actaatggca
     7741 ttatttgaag catttaatat agatttatca aaatgttcaa atgaagatat aaatgatggt
     7801 tcgatttttg gaaggggatt tggagcatct ggtggacttg ccaaatcagt acagaactat
     7861 attgctgaaa aggggcttag ttttgatttt gaacctataa aagtatctgg tccaagacaa
     7921 attaaaaaga caatgacaat ggctaaattg ggaagattag aaggtaattt tatagaagga
     7981 atgatgtgtg aagaaggttg tattaatgga gccggtaagt ttttatcagg tgtaaaagcc
     8041 aaaaatactt ttgatagaaa aaatggacaa tctactaaaa agagtgtttt atctaatgat
     8101 aagattaaag aatttgaaga tgtaaattta gaaagataat tgttttggta cagtcatttt
     8161 tttattatgc cacaaatatg cctaaaattt gcccttttta tatgtgtatt ttacagagtt
     8221 aaggttgcta tactataaat atgtaataaa taaaatttat aggagctttt ggatgaggaa
     8281 aatagtatta aaagatatcc tgtttttagt tactacatta tctataatag taatattatt
     8341 gcttgtaaca aatataacta ctaatagtaa gataaaatca acaagtgaat cttatttaaa
     8401 aagtgacaaa aatagtgtga ggcaaaatgg tatccagagg agcacaaaga gtagcacaaa
     8461 aaatactgca tttaagacta ctatactaaa cactggaaag tctgattgca tattggttga
     8521 gataggtaac aaagtcataa tgattgatac aggagaagat aaaaatggaa aacaaatagt
     8581 ggataggtta aaagaaaaag gaataaatac acttgactat ttgattttaa ctcatttaga
     8641 taaggaccat ataggtggag tagatagtgt gttatctagt gttaaagtaa agaatattat
     8701 acaagcaaat tataagaaag atagtaagca atatgatgaa tatattgact cacttaaaaa
     8761 agctgatata gaaccagtgc tactaaaaga taatatgaat attgtaatca atggtgcaga
     8821 aataaacata catccggctt caaaaagcaa gtacgagagt tcaaatgatt attcaataat
     8881 cactaatata agctatggag cacataagtt tttatttgca ggagatgcag aggaagaaag
     8941 attgtcagag tttataaatg gaaatacttt aaaatatgat tttgttaaaa tgcctcatca
     9001 tggaagatat gacaaattaa ctgaaacatt tttagagtct atttcacctc aatatgctgt
     9061 tattacatgt tcagagaaaa aagaaccaga ggaaggtgtt ttaaaaatat tggaaagatt
     9121 gaatataaaa acatttttga cttctaatgg agaggtagtt atcaatagtg atggtaagac
     9181 attgagtgtg aatcaataat ttttttaaaa atatctaaaa aaatttaaaa aaatcattag
     9241 caaatattac cccttaaaca tagtatattt taggagctga aactccacat acaaaatgac
     9301 taggaggtaa catattatgt tggatagatt ttttggtgaa ggcggatttg gtggatgtgc
     9361 ttggtggata ataatattat tcttcttatt cttagcattc caagattgtt gggctgaaat
     9421 ggacttatgt gcatggatac ctttcttaat attattatta atactttgtg aatgtggtga
     9481 cgtttttgat ggaggatgtg gatgctaaaa aaatcaattt agatgattta ataaagctta
     9541 tggtgggtat aaataaaata ccaaaccaat cacaatctag tgtttgaagg tagtcggaaa
     9601 tcccccgcta ccttcttttt tttattgtta aaatttattt ttgaattatt tcatttacat
     9661 ataataattt ttacgataaa gtctgatata attaaaaaga aaataaaatt tatttatagg
     9721 agatgtaaaa atggctatag tggataagat tttcaatgag ataaaactta tggttgcaag
     9781 acttttattg ggaaaaaaat acagtgaata tgaagaaaaa gatttagtgt ataatacaga
     9841 agaagaagtt atacttataa ctttaaaaag attagttttt cagggaaatg taaacgaagc
     9901 agaagaaatt ttatttgata aagctaagag tgtaaatagt gaaaatatgc agtatatagc
     9961 aatagaattt tatactatgc ttatggaaaa gactgatgaa gaattagaag ctatgaattt
    10021 ttctaaacaa gaagtttatc aaggtataga agatattaga aaagtattga atttagaata
    10081 aaagatatat gaaaatattg aaataaatta atgctaaggt gagaatatta tacttatata
    10141 taaaaatata gtattcttat tttattagtt atataggtat atcttattta ccataaaact
    10201 atcttgaaaa aaattaatct taattgtata atattacttt gagtgaaaaa gtattaacat
    10261 ttttttataa gatgttttac taaaaaaata tatataaata tactgttatc aacaagaaat
    10321 ttaatttagt gaggtgttaa gatgaaagta ggatttgacc acaaaaaata tttagaagag
    10381 cagtctaaat atatcttaga aagagtaaat aattttgaca aactttattt agagtttgga
    10441 ggaaaattga tgggagacct tcatgcaaaa agagtacttc caggatttga tgaaaatgca
    10501 aagataaaag tattacaaca tatgaaagaa aaagttgaag ttgtaatttg tgtctatgca
    10561 ggagatatag aaagaaacaa aataagagga gactttggta tcacttatga tatggaagtt
    10621 ttaagattaa tagatgattt aagaggttat gaactagatg taaatagtgt agtaattact
    10681 agatttgaag gacaacctgc tacaactgta tttataaata aattagaacg tagaggaatt
    10741 aaagtttata agcattatcc aacaaaggga tatccgtcag atgttgagac tatagttagt
    10801 gatgagggat atggagcaaa tgaatatata gaaactacaa agccaatagt agtagtcaca
    10861 gcaccaggac ctaatagtgg aaaacttggt acttgtctaa gtcagttgta tcatgaaaat
    10921 aaaagaggta atgtagttgg atattctaag tttgagacat tcccagtttg gaatgtacct
    10981 gtaaaacatc ctttgaatat agcttatgaa gcagctacag ttgatttaaa agatgtgaat
    11041 atgatagatt cattccacct tgaaacgtat ggtgaaatgt cagtaaacta caatagagat
    11101 ttggaattat ttccagtgct taaaaaaata atagaaaaga taactggaaa agaatcaatt
    11161 ttccaatctc caactgatat gggtgttaat agagttggct ttggaataat agatgatgaa
    11221 gtaataagaa aagcttctat agaagaaata ataagaagat actttaaaac tgcctgtgag
    11281 tataaaaagg gacaagttga taaaggtgct tatgatagaa tgaaaatgat tatggaagag
    11341 cttaacttaa agccagaaga tagaaatgtt gtattacctg ctagaaacta cagtaataaa
    11401 ttgaaagaaa gtgccgacaa gaatgatact tgtcctgtag ttgcattaga attagaagat
    11461 ggtacaatat taactggtaa gggttctgat ttaatgaatg gaactgcagc agtagtatta
    11521 aatgccatta aacatttagc caatatatct gatgatatgc acttaatatc acctgtaata
    11581 ttagaaccta tcataaactt aaaaacaaag actttagcta gtagaaatgt ttcacttagt
    11641 tgccaagagg tgttaactgc acttagtatt tgtgctgtaa ctaatccaac tgcacaattt
    11701 gctatggaaa agttagcatt attaaaaggg tgtcaagctc attctactac tatattaaat
    11761 agagatgatg aacaaacatt tagaaaactt ggtatagatg taacttgtga cccagaatat
    11821 ccttcacaaa atctttacta tagttaaaat tatataaaaa aatatgggct gttttaaagt
    11881 aatagtttga gcagtccatt acaattataa taaaatcagt aggctgtctt gtataagaca
    11941 gtcttttgtt tttaaaacat cccataaatt aaatatatat actgttatcc ataaggaatt
    12001 ttaaatttag ttccttggaa tacctattgt aaagctttta tatagttttt gcaagtgttt
    12061 ttaaggattt tttataaatt atattgaagt taatggatta tagatggttt tatttatgga
    12121 aaatatgaat atataaagaa aataatgaaa aaataccaaa aagaaacata agtttggtat
    12181 aattaaaaag taatataaat aaaattaatc tatttatact ttaaaaggtg ataataatga
    12241 aacattatag aaaaataatt catatagata tggacgcttt ttatgcatct atagaacaaa
    12301 gagataataa aaaattaaaa ggaagacctg ttattgtcgg tggaaatcca caaagccgag
    12361 gtgtggttgc aacctgttct tatgaagcta gaaaatttgg tatccattca gctatgccat
    12421 cagctgtagc ttacaatagg tgtccatatg cagtttttgt aagacctaga tttgatgttt
    12481 ataagagtgt gtcagagcaa ataagagata tattttatag atacacagat ttagttgaac
    12541 cattatcttt agatgaagct tacttagatg taacaaaaaa taaaaaaaat attgattcat
    12601 caattgagat agcaaagcaa ataaaaaaag atatatttag agaagttggt cttacttctt
    12661 cagctggtgt gtcatacaat aagtttcttg ctaagattgc atcagactta agaaagccaa
    12721 atgggttaac tgtaataacc gaagaaaatg cccaggactt tttagataaa ttacctgtga
    12781 ataaattttt tggtgttgga aaagttactt caaatactct taaaaattta ggtataaaaa
    12841 ctggatatga tttaaggtgt ttaaatttat ttgaacttga aaatatattc aaaaaaagag
    12901 gttatgaatt atataaattt gctagaggaa tagacgatag accagtggaa ccaaataggg
    12961 ttagaaaatc tgttggggct gagactacat taagtcataa tttggatatt gatgaagaag
    13021 aaacacgcaa cattcttgat gaactttgtg aagaagtatg tcatagatta aaaaactctg
    13081 agaagtttgg aaaaacatta acattaaaaa ttaaatatga ggactttaca aagataacta
    13141 gaagccttag tttagaacac tatattgacg aatataatga tataagaagt ggtgtagata
    13201 atttgttgag aaatgttgag gttaatggaa aacaaattag gctattggga gttacaatat
    13261 caaacctaag tgataaaaaa gaaacttata aagatattac attatttgaa tacatggata
    13321 gtatccaaat gtgagttttg tttaaatgaa ataacactag ctttaatact atataattga
    13381 ggctagtgtt attttatgaa tatttttata ttttttgttt tttgacattg tatattatat
    13441 actatatata aatactttat atttgtagca atattcagac aaatagtgac ctaaaaatcg
    13501 tactttgttt acataaataa aatagtatga tataattata aaaacaactt ataatattgg
    13561 agaaggttgc ttgttcgaaa aaggggatga taaattatga tagagataag aaatgtaaca
    13621 aaaaaaatag gaaataatgt tatattagat gatatttctc tagttgtaga aacaggtaca
    13681 ttggtagttt tgattggttc aagtggttgt ggaaagacta ctactttgaa gcttataaac
    13741 aaattaataa aacctacatc tggtgagata tatattaatg gcaaaccaat ttctcaggaa
    13801 aatgaaatag agcttagaag aaaaatagga tatgttatac agaacacagg cctattccct
    13861 catcttacaa taaaagaaaa tatagagcta attccacgcc taaaaaagga aaaatccgtt
    13921 gaagaaattg aaaaaagaac gttgcaacta cttgagatgg taggacttga tagtgatgaa
    13981 tttttgaata agtatccttc agaacttagt ggtggacagc aacaaagaat cggtgttgca
    14041 agagccattg ctactgatgc tgaaataata ttgatggatg agccttttag tgctttagac
    14101 ccaataacga gaacatcttt acaagaacaa ttattttctc ttcaagatga attgaaaaaa
    14161 actataatat ttgtaacgca tgatatggat gaggctttaa agatagctga taaaatttgt
    14221 attatgaagg atggaagaat agcacaatat gatactcccg aaaatatact tagaaagcct
    14281 gcaaatgact ttgtaaaaga ttttatcgga gaagatagag tttgggataa tccagaatat
    14341 ataaaagcaa gagatattat gataaaaaat cctattgctg ttaattctac tagaactgta
    14401 actcaaggaa tagaaattat gagaacgagt aaggttgata gcttactaat tatagataga
    14461 gcaaaaacat taaaaggtat tgttactgta aaagatatga aagatattga tgataagtca
    14521 atattacttg ctgatattat gtcaagtgag cctttgcatg taaatgaagg ggataattta
    14581 gtagaaatac taaatgtaat gaatcgtaat tcggttggat atattccggt tatttctgat
    14641 gaaaataaac tggtagggct tattactaga agtagtttac tttctgtttt aagtgaacaa
    14701 ttcttagaaa tggaggtgag tgttcttggc taattttttt aactttatac tattacaaaa
    14761 agataagatt atagagcttt taatacaaca tatgagtcta actgttacat ctattttaat
    14821 agctataata gttggtgttc ctcttggaat aattatttca agaatctcat ctcttagaaa
    14881 gtttgtactt ggatttgtaa acttagtcca agcagttccg tctatggcac ttttgggtct
    14941 tcttgtacct atacttggta taggaagtaa accagccata tttatggtag tggtttattc
    15001 attactacca attgtaaaaa atacgtatat aggtataaca agtattgacc cagtagtatt
    15061 agaatcagct aaaggtattg gtcttacaag aaatcagaca ttatttaaaa tacaattccc
    15121 tttagcactt cctataataa tgggtggagt tagaatatct gcagttacag ctgttggttt
    15181 gatgactctt gcagcattta taggtgctgg tggtttagga tatttagtat tttcaggggt
    15241 tcaaactgta aataataata tgattttagc aggggcaatc ccatcatgta taattgcact
    15301 gttagttgat tatttattta gtaaaattga agttgcagtt actccaaaag gattaaatcc
    15361 aaaagcacct aagaagaatt atatagcact taaagtaata tctgtagtgg ttgttgtttc
    15421 aatgttgttc gttgttttta gttctagttt ttcaagtaaa aaagatacaa taactattgg
    15481 ttctaaagat tatacagaac aacttatact tggtaatgtt tatgctgaat tagtagaaaa
    15541 aaatacgaat cttaaagtta agaagaattt aaatctaggt ggttcatctg ttgcgtttaa
    15601 tgcaattaaa tctggtgagt tagacatgta tgttgactat acaggtacac ttttggtaaa
    15661 tgtaatgaaa catgctccga ttaaagatgc tgatgaagca tataatgttg taaaagatac
    15721 tatggaaaaa gaaaatcagt taactttact tgaccctctt ggatttaata atacttacac
    15781 attagctatg atgcctgaaa ctgctgaaaa gtatggaata aatactattt ctgatttgac
    15841 taaatatggt aaagaattta cattctcacc aactttggag tttgaaaata gagaagatgg
    15901 tcttgtaggg ctttctagag attatggttt aaaattcaaa gatgtaaaag caatgaatgg
    15961 aagtttaaga tatacagctt tagataataa tgaatctcag gttatagatg catttttaac
    16021 tgatggtctt attaaaaagt ttaatcttaa gatattagag gacgataaaa atttctttgt
    16081 accatattat gcagcaccat tagtaagaga agatactttg aagaaatatc ctgagttaga
    16141 aaaagttatg aatatgcttt caggaaaaat aaatgaagaa actatgagag aacttaacta
    16201 tcaagtggat gaacttggta aatcaccaga agaagttgct cattcattct tagttaaaga
    16261 aggcttagta taaaaaatta atagtttata tcaaaaaatt taagagagtg tctcaaaatg
    16321 aactttttag ttcatgaggc actctttttt atatgaaatc aaatatattt tatcatttca
    16381 acaataaaaa agaagattat ctttattttg agacagtctc ttatttttat gtataccaaa
    16441 accataccta cgatttttat ttataattaa gtttcaaata gaatgaacaa gtacaaccaa
    16501 ttttgaatat aaatatagta aatgtgctta tatacgattt tattgtctgg ttgattgata
    16561 ttgatagata gctttcttta ttgaatcgaa gggaggggga atttgttatg gataactata
    16621 agaaagtgaa gcaagtattg tggataattt tatttgctaa ttttgcagta gcattattaa
    16681 aaatcattat tggtaatcaa ataaaaagct atagtatgac agcagacgga tttcattctt
    16741 tgtcagatgg agcatctaat atagtggggc ttataggtat tttctttgca tctaaaccaa
    16801 aagataaaaa tcatccttat ggacataaaa agtttgaaat tataaccagt ttatttataa
    16861 gtggtatgtt gtttgttata gcaattaaga taattcttag tgcagtgtta agaatagcta
    16921 atccagttgt acctgctata actatagaaa gtttaattgc tttaattatt acacttttta
    16981 taaatatttt tgtatgcatg tatgaatata gaattgggac taaactaaat agttatgttt
    17041 tgatttcgga ttcattgcat acaagaagtg atatatttgt gtctctaggt gtattggtta
    17101 ctttagttgg tgttaagtta ggatttccag taataataga atctatagtt cctattatta
    17161 tttctgcatt cataatttat tcggcttatg gaatatttag gccatctatt ggaattttgg
    17221 tcgatagagt ggctgtagat gaggattata taaaagaaat tgtgtttgaa tttaatgagg
    17281 taagggatgt tcacaatatc agaagtagag gtagcaaaag ttctatttat attgacatgc
    17341 atgtaatggt agacccattt ataagcgtag agcaatctca tgatttaaca cataaaattg
    17401 agaaacaaat acaagaagaa attaatgaaa atgctcaagt aatagtccat attgaacctt
    17461 tttatagttt ttaacttagc tataaaatac aagttataaa aaaatataat ttataaaaaa
    17521 aatattatac cataaataat ttataaaaat tatttatggt ataatatttt ctataaagaa
    17581 attaagtctt aatatatcta aggaggaatt tacaatgaga tacgttgaat atggaaagac
    17641 agggaaaatg gtttcagtag ttggctatgg aggattaagg tttgatttag aaaaaagtaa
    17701 tcaagaaaat gctgatttag tcaaatatgc gtatgaaaaa ggtattaatt actttgatac
    17761 agcaccaggg tattgtgatg acagaagtga agatatattt ggactagcct ttagacaaat
    17821 gataaaggaa ggtaagaccg atttttatgt atcaactaaa gaaaagccaa aagcatgtga
    17881 tacatcagaa aaagctatag aggctgtaaa aaaatcaata gaacgattag gcgtatctaa
    17941 aataaatttt tatcatgttt ggaatattag aaagatggaa cattacgaac tagcaatgag
    18001 acctggaggt caatatgaag gattattgaa atgtaaagaa gaaggattga tagaccatat
    18061 agtattttca tctcatcaac caggagatga ggttatagat attctaagtg aaaataagtt
    18121 tgaaggtgta actatgggaa taaatatatt aaactttcca tataggctaa aaggtgccaa
    18181 atatgctgtt gataatggat atggtgttgt ggcaatgaat ccattaagtg gtggaactat
    18241 tccaaagtat aataaagaac tttcttttct atcaaaagat ggcgaaagta ctatagaatc
    18301 agctttaaga ttcaacatag gaatttcaca aataagtata tctttgatag ggtttaataa
    18361 aaaacaagat atagatgatg catgtaaaat tgcagacgaa aatagaattt attcagatga
    18421 ggatatacat gatattgaga ctagattaaa taagaatatg aacgaaatat gtacaggttg
    18481 tggttattgt aaagtatgtc caaaaggtat taatacccca gcctatatgc ttttttataa
    18541 tgaaaagcag atgtttaaaa agagtgatga agaaatgaca aagttagttt atggcttagg
    18601 acattggaat tacacaatga atagtaaggc aaaagctaaa gaatgtatat cttgtggaaa
    18661 atgtgaagtt gaatgtactc agcatttacc tataatagat agattaaaag aaattaaaaa
    18721 atgggaagaa gatggagcta atagtgttaa agtctaatta attttatact atatttgaaa
    18781 tttgtatagt atttagtaat gttttaaaat atagttttaa tatttaagga gacagattat
    18841 aattttgtct ccttaaatta tgctttaatt tgttatagtt taattccata agtaacattg
    18901 tatattttta tataaagttt ttcaaatatt ttacattaat attgcttaca aattctcatt
    18961 ttatacaaca ctaatctatg ttatataaac aatacttgac tgattataac atcaataaag
    19021 taaatattgt ggttgtaaat aaagagttat tcaattacaa taaaacaagt aagaacatta
    19081 tgaagatggc tattaaatat aaggaataaa ttgtaggtgt cagcaaatcc tatataatga
    19141 atggatggtg atatattgat gagtaaaata ttaaaatata aaaacgagat gtttttgttt
    19201 atattagttg taataactta cttaataata actaagatat ttttttctaa gactactata
    19261 ttttatgatt taaacaatac ttatgatgta ttgttagata cagatacagg agttttattc
    19321 aatttaaatg tatttgctat aagtcaagac aatagtaagc atatattgtt ttcagcaatt
    19381 atatcaattt ttgcatatcc aatataccta ttttgtactt caatagcaaa tcctgggaca
    19441 acagatttta atagtgccta tgggtttgga ctaatttgtc tacaaataat aactagtgct
    19501 atgtcaataa ctttagtctt taatcatatt aaaaagataa aaatgcagag attaacttta
    19561 attttactta ctatgataat gatattttct tttccacagt tatttatgac tttaaatgta
    19621 gagagattta tatatagcca attttcatta atatttttca tagttattgc aaataagatg
    19681 aaaggaaaaa attcttattt ggtagaatta gcagctattc ctctatttgg aataactatt
    19741 agtaatatat atttgtattt ttttaatatg atatttgagt ttaaattaaa aataggaaaa
    19801 atgttaaaac atttaattac atttatccta atggcatata tttgtgtagt ttcaacgaag
    19861 tcttatgaga gttttatgaa ccttggaaat gtaatacagt atgatacgaa atttataagt
    19921 ggagaaccaa ttttggaaaa gattgcaatg attatagaga gattattgta ttcggttttt
    19981 tattttcctg gagcaagtat taaaaaaggg ttatttttgc aaaatggaga agttgctaca
    20041 ataccagtaa ttcttacatt attagcttta tgtttttgtg ttttatcagt tattgaaaat
    20101 tcagaaaaaa gagttcctaa gctatgtatg ggaataatta tattcaatct aactttacat
    20161 ggtatagtag gatataatct agtcaattca agtattatgg ctataaattt tagttttgca
    20221 gttataattt tattggctta ctttacgaaa gcccttagaa aaaatgaaaa gaatatgtat
    20281 aatatatttc tatcgctgtt attggttact atagtaatca gtaatgtcaa tggatttata
    20341 gaaattttaa acatagggat aaaatcatat cctgtttaaa aaataatatt gaaagggtag
    20401 taagtttatg aaacagacca atacaagtat aaggcttctt actaaaattt cagattatat
    20461 aaagttaatg agaataaagc aatatataaa gaatttcttt gtattttcag ctataatttt
    20521 ttcaaacaac atactaaata taaatttatt tttaaatacg tttattgcgt ttgtgtgttt
    20581 ttgcctaatg tcatcatcag tatatgcact gaatgatgct atagacatgg ataaagataa
    20641 aaaacatcct aaaaaatgta atagaccagt ggcaagtgga agaataagca aaaaaagtgc
    20701 taatatacta tttgtagtat tagcgttaat ttcagtctgt ttatcaacag ttgttagttt
    20761 taatctttct ataattctca gtctctattt gataaacaat atattatatt ctcttaaact
    20821 aaagaatata atactattag atgtgttttc aatatctctt ggttttatac ttagggttta
    20881 tgcaggatgt gtagccataa gtgttagttt atcaaattgg ataattttat gtacattttt
    20941 cttatctctg tacttagctc ttggaaaacg taaaaaagaa atagaaactc taagagatga
    21001 tgcagttgaa catagaaaaa tattggaaga ttatgacata gaaaatctaa atcaaatgat
    21061 gatagttata ttaagttcta caattgtatg ttatgcattg tattctacaa gtaatccaga
    21121 aaagccacat atgatattta caacaatatt tgtagtttat ggtgtactta gatataatta
    21181 tataattaac actacaaatg aaaataatcc tactgatatt gtcctaaaag ataatgcttt
    21241 aaaaataaac gtaatcttat ggataattac atgtttaata atattgattt tttagtgata
    21301 tttttagtga taggatgggg aaatacttat gaaaaaaagt gtattattac ttgatgtaga
    21361 ttatactgtt ataaatactg atagcatgat agattttttt atttactctt taaaaaataa
    21421 aacctttaaa actattataa agttgccata cattattttt attctattta tgtatttaat
    21481 tagaatgata cccttgaaga aggcaaaaga ggcaatcttt tatccaatag tagattttag
    21541 tgaagaagat ttaaaaaagt tttttgatga ttgcataatg aaaaaaatta acgaatctat
    21601 gaaaaaggtt atttacaaaa ataaagaaga agataatgtt ataattatga taactgcatc
    21661 tccatatgca tatatgaaat attttaagta ttatggtctt gcagacgagg ttataggcac
    21721 ggagtttttt tatgaaaatt caagatataa aaatcaattc attggagaaa actgtaaggg
    21781 aattgaaaaa gtaaaaagaa taaaggctgt attaggtaaa cttgggatag agattgatta
    21841 tgaaaattca tatgcatatt cagactctaa gagtgattta ccaatgcttt cattgactaa
    21901 aaatgcattt ttagttagta aaaaggatgg tgaggttata gagcaaataa attcataact
    21961 taatgtcact tagaatagga gggaatagtt tgggatattt acacatatta attttatcta
    22021 tggttcctgt aacagaattg aggggagcca ttcctatagg tattgcaatg ggcttaaatc
    22081 ctatatgggt ttatgtattt agtgtaatag gttctacatt ggtatcgatt cccttgatat
    22141 tgacattcag acatgtatta caatttttaa gagggaagaa actatttaaa gggattgctg
    22201 atgtaattga tagaaaaata aactcaagaa tgaagaaatt aaaaagtgtt tcgataattg
    22261 gtataatact atttgtaggt ataccactgc caactacagg aacatggact gcatctgcta
    22321 tagcttccat attaaaaatg agaataaaag atgcttttat gggagtattt cttggcaatt
    22381 tgttatcagg ggttatagtt tcagctcttt ctttacatat aatataaaac tatctaagta
    22441 atatacttgg atagtttttt tatgagtata tgtgaaaaat ttttaataat aaataaaaaa
    22501 tgagataaag tatttaactt cagttagttc taaaatgttt actatggcaa aagaaatata
    22561 gtatagtatt acttgtaggg aaagtactct aaatttgtct gctaataaaa tgaaattttt
    22621 atatagaata aaattttagt gatacatttt aattattgga ttgaggaggt tttaaaatgg
    22681 aaaattcaaa cactaactta ggtagtgaaa gtgtgggtaa attattattt aaacttgcta
    22741 cacctgctat tatcgcacaa attgtaaatg ttttatacaa catagtcgat aggattttta
    22801 ttggtagaat ggaaaatgga gaagttgcta tggctggtgt tggagtggca tttccaataa
    22861 taattataat aactgcatgt agttatttaa tcggtatggg aggaggtcca ttagctgcta
    22921 taaaaatggg tgagcaaaac aatgatgagg cagagaaaat aatgagtaac agtttttctg
    22981 tattggtgat tttagcaata cttttgacta taggttttaa gattggaaaa gagcctttac
    23041 tttggatgtt tggagcaagt gaatctacaa ttggatattc aatggactat ttaaatattt
    23101 atttaatagg tacagtgttt gttcagattt caatgggtat gaatactttt ataaataccc
    23161 aagggtttgc tacaactgga atgatgacag ttgctatagg tgctttaata aacataatac
    23221 ttgacccgat ttttatattt ggctttaata tgggtgtaaa aggagctgca ttagctacta
    23281 taattgcaca aggcgtttct gctatttggg tacttatgtt tctctttgga aagaaaagta
    23341 tacttaaaat aaaaaagaag tatatgatac caaaagcaag tatcatctta ccagtgcttg
    23401 gcttgggaat ctctccattt ataatgcaat ctacagaaag tttagtactt atagccttaa
    23461 atagtaaatt acaaatgtat ggaggagatt tagcagtagg ttcaatggcc ataatgagca
    23521 gtataatgca aattcttatg cttcctaata tgggggttac acaaggagca caaccaataa
    23581 taagttataa ttatggttca ggtcaacttg atagagtaaa aaagacattt aagttgtgtt
    23641 tattgtcatg ttttacatat tctactattt tatggctttt attaatgata tttcctgcat
    23701 tttttgttag tatatttaat aagaatccgc agttacttag tatgactagt tggagtataa
    23761 aaatatattt tgctggtgct tttatgtttg ggattcaaat agcttgtcaa cagacatttt
    23821 tagcacttgg aaaagcaaca atatctttgg ttttagctct acttagaaag attgtacttt
    23881 taataccttt aatatttata cttccaacat tctttaatga aaaacttttt gcagtaattt
    23941 tagcagagcc agttgcagat ataacagccg ctactataac agcaatttct ttctttatat
    24001 tttataaatg ttttctatca aaacctaaag caataaaaga ataagatata caatataaat
    24061 tttttatgaa aatattttat tagataaaaa ttagaatttg tattttaatt taataagata
    24121 ttttctataa tgtataaata tatgaagttg aatttatttt aaaaattata gtaagaaaaa
    24181 tgtaagtatt tgcaatatta atggtataat atttacagat atgataatca ataagaggaa
    24241 aggatgttta taatggaaaa tgatttaaca atgcaagaat tacttgacca gcaagaacaa
    24301 gtattcagca aagtgaaagt tggagaattg acaactggaa aaataactgc agtgagaaat
    24361 gatgaagtac aattaggatt agactatggg tttgatggaa taatacctat aagtgaattg
    24421 aacatagaaa aaaatcaata tatagaagat atataccaca taggtgatga aataactgct
    24481 gtaataacaa aagtatctca aaaagatggt acaataactt tatctaaatt acaacttgac
    24541 aaaagaaatg attttgccga gttacaaaag gcttatgatg aacatagaat aataactgta
    24601 aatgttgaaa agaatataga taaaggtgta tttgctaatt acaatacata tacatttttt
    24661 ataccaattt ctcaacttga tacaaaattt attacagata catctaaatt tgttggtctt
    24721 aacttagaag tttatataaa agaattggat gttagaaaaa atagacttgt agcatctcat
    24781 agagatgtat tacaagagcg tataaataaa gagagagaag aaagaagagc tcaaattaag
    24841 gcagaaaaag aagctgaaag agcaagaatt aagcaagaaa gagaagaaga aaaagctcgt
    24901 atcaaagcag ctaaagaaga cttatttaat tctcttgaag ttggacaaaa aagagatggt
    24961 aaggtgacaa agataatgcc ttatggtgca tttgtggata ttggtgggat tgaaggatta
    25021 gcacatataa ataatttagc ttggacaaga gttgaaagtg ttgaagatgt tgtttcagag
    25081 ggacaagaag tagaagttta tgtgttggat gtaaataaag agactaaaaa aattgccttg
    25141 gcattaaaag acataaataa tgacccttgg gatttaatag caaaagaagt acaaattgat
    25201 gatgttgtca atgttaaagt tcttagaata atagaaaaag gggcttttgt tcaaattaaa
    25261 gaaggtgtag atgcgtattt accaatatct gaattgagtg atactagagt ggctaaagtt
    25321 actaatgttg ttaatattgg agatgaggtt aaagttaaga ttcttgattt taaaccaaag
    25381 actaagagaa tgttggtttc aataaaagaa gcaactagag agccagaaga ggatataaca
    25441 gaatacctag aagtagagga atctttagga agtattggag aattatttaa agataaattt
    25501 aaagatttag aagtgtaaaa taattgaaaa tggggctgtt ttaaaacgtt acactgtcta
    25561 ttatgacagc tttagttttg aaatagccct ttagctattt tcacgaattt atgtaaaata
    25621 ttaggaggaa atttaatgaa aaagtctatt atggatgtac attgtcacac tctaataagt
    25681 ggacatgcac atagtacttt caaggaaaat gtcgaagagg cgagtaagaa gaatataaaa
    25741 tacttaggaa tatcagacca tggacctaat atgccaggag gaccacatcc attctatttt
    25801 tataatttgc atttgcttcc acgtgaagtg caaggcgtaa agattcttag aggaatagaa
    25861 ggaaatataa tggattataa tggtaattta gatgttcaag aagatatgtt gcaacatttg
    25921 gattatataa tcgcaagttt gcatagacct tgtatagctt ctggtacaaa agaagaaaat
    25981 acaaatgcta ttttaaaagt tatggataaa cctaaggtaa aaataattgg acatccagat
    26041 gacagtaggt atcctttaga ttatgaacct atagtaaaaa aagctaaaga taaaaatatc
    26101 cttttagaaa taaataattc atcattaagt tcaaactctc atagaacggg tacttgggaa
    26161 aatgtaagtc atatgttgac attgtgtaaa acatatggtg caagagtaat tcttggtact
    26221 gactctcata tatgttattc tataggagaa tttgaaaatg cagaaaaagt tttagaagca
    26281 gtagattttc cagatgaatt agtcataaat tatcatgaag atgaaattat agaatttttt
    26341 gatataaatt tttagaatct tggaagtgaa aaaatttgag taaaaataag tttatctata
    26401 tgaattatta tgacaatggt tattttaaaa aaggaatgac tatatatatg gttttagcac
    26461 ttataatttt agctacaatt tttatatatt caacgacaat attatatatt ttatgtataa
    26521 taacagcagt ttttctattt aaacaaggtc gtgatttttc aaataaatat gagggaaaag
    26581 tatatattac tctcgataat cattcaatat taataaataa tcaatgtata ttcagtataa
    26641 aatctaaaca aagtcaaaag tttaattata agataataga aaaaatagaa gtagtaaaaa
    26701 atatattaaa tatatacact gacgaatcta attataaaat tagattaagg gcattgagtt
    26761 tggaagatga aaaaaaatta ttgaatatca tagatgaaaa gatgaaaaag tttaaggcat
    26821 aatatcatac tgttttcaat agttagcatg ttttatagaa ttgcttatca aaaataaaaa
    26881 attgagataa ttattttttg tgttgacaat acattttaat gtgtatataa taactattaa
    26941 atcaaaatat ttagaaaatt taaatgatta aaaaagtgat gaatagaagt agtaagaaca
    27001 atgaaacttt cagagagcta aaggatggtg tgatttagta gttgatagtt ctgaacttgt
    27061 ctaggagctg ttttctaaga tttaaatctt agaataatcg gagtaattcc acgttatagg
    27121 aaatatagtc attataatta ttgtattggc tattactaag ggagcttttt agaaagctaa
    27181 atagagtggt accgcgagca aaacctcgtc tctaatttta ttagagatga ggtttttttt
    27241 attctaatga taaaattgac atttatcctt atgaattgtg caggattgcg tcgatatgag
    27301 gtatactgaa tacaaaaaac agaaaaaggg ggaaataaca tgaagtgtgg aaagtataaa
    27361 aaatatgata aaatgcaaat agtaaatcgt aaatggccag ataatgaaat atttaaggct
    27421 ccaatttggt gtagtgtcga tttaagagac ggaaatcagt cactgccaac acctatgagt
    27481 gtaaatgaaa aagtcagaat gttcaaaatg cttattgata caggatttaa agaaatagag
    27541 gtaggatttc catcagcatc aaatacagag tatacatttt taagaaaatt aatagatgag
    27601 aatatgattc cagatgatgt aactatacaa gtacttacac aatctagggc tcatcttata
    27661 gaaaaaacat ttgaatcaat aaggggatgt aaaaaagcaa ttatacattt atataactct
    27721 acatctgttc ttcaaagaga tgtggttttt aatatgagta aacaagaaat aatagatata
    27781 gcagttgaag gagcaaaatt atttaatgaa gaagtaaaaa aatatccaga aacagaattt
    27841 acttttgaat attcaccaga gagttttaca ggaacagaga tggattatgc acttgaaata
    27901 tgtgaggcag tgatagatgt ttggaaacca actactcaaa aaaaagtaat aataaatctt
    27961 ccatcaacag ttgaaatggc aacaccaaac gtatatgcag accaaataga atggttttgt
    28021 aaaaatataa gttgtaggga ttctattata ctaagtttgc atactcacaa tgatagagga
    28081 acttgtacgg ctgcaagtga acttggatta ttggctggtg ccgatagact tgaaggaaca
    28141 ctatttggaa atggtgaaag aactgggaat atggatatag taaatgtggg acttaatctt
    28201 tatacacaag gaatagaccc agagctagat tttagcaata tagataagat aataggtata
    28261 tatgaagatt gtacaaaact tatggtacat gatagacatc catatgcagg taatcttgta
    28321 cattgtgctt tttcaggttc acatcaagat gctattagaa aaggcatgat agcaatgaaa
    28381 aacagagata atgattactg ggaagttcca tatttaccaa tagaccctca tgatattgga
    28441 agagaataca aagaaattat aaggataaat agccaatctg gaaaaggagg agctgtttat
    28501 ataatggaaa cagattatgg atttatgata cctaagaata tgcattctga ttttggaaat
    28561 gtagtcaaaa tggaatctga tagaattggg gaagaactta gtagtgaagc aatatttaat
    28621 ttgtttaaga aagaatatat tgaagttgag agcccttata aagttaagaa gtataaaata
    28681 aaatcaatgg atgaattaaa ctatgaaaat gatgattcta atgatactaa catgattgag
    28741 atgactgcaa gaataagtta tatgggaaat gaacaaagga ttgttggtat aggaaatgga
    28801 cctgtagatt catttaataa tgcactaaag caatgtggca tgaaagatta taaatttaga
    28861 tattactggg aacatgcatt agaggaaggg tcacattcaa gaggggtagc ttatgtagga
    28921 atagagcaca ataatgaagt ctattttggt gtaagtatat cggaaaacat aaatacagca
    28981 gctattaatg cacttatgaa tgcaataaat aaaagttata ttgaggagga aataaaaaat
    29041 ggggatgact atgacgcaga aaatattagc caaacatgct aaattaaatg aagttaagaa
    29101 agggcaatta atcgaagcag atttagatgt agttttaggt aatgatataa catcaccagt
    29161 agccattaga gaatttgaaa aattaggaat tgaagatgtt tatgataaga ctaaagtagt
    29221 gatggtttta gaccacttta cacctaataa agatataaag agtgcagaac aatgtaaatt
    29281 tacaagaagt ttcgcaaaat caaaaggagt tgtaaatttt tttgatgtag gagatatggg
    29341 aatagagcat gttcttcttc ctgaaaaagg tatagtaact gctggagatg taattatagg
    29401 tgctgactct catacttgca catatggagc attaggagca ttttctactg gtgtaggttc
    29461 aactgatatg ggagcaggta tggctacagg aaaatgttgg tttaaggttc ctggagcaat
    29521 aaaatttgtt ttgaagaata aaccaaataa atggataagt ggtaaagata taatacttca
    29581 tataataggg gagataggtg ttgatggagc actttacaag tcaatggaat tttgtggaga
    29641 tggagtagaa tacttatcta tggatgatag atttactatt tgtaatatgg caatagaagc
    29701 aggagcaaaa aatggaattt ttccagtaga cgataagact atggaatata taaattcaca
    29761 taagtgttca actatgacaa aagatgtaaa tatatatgaa gcagatgaag atgcagtcta
    29821 tgatgaagta tacgaaatag atttagctga actaaaagaa acagtagcct ttcctcatct
    29881 tcctgaaaat actagaacag tagatgagat agataaggat ataaagatag accaagttgt
    29941 aataggctct tgtacaaatg gaagaatatc agaccttgaa gtagtagctg agataatgaa
    30001 aggcaaaaaa gtagcagatg gagttagagt tatgatattt cctggaactc aaaaagtata
    30061 tcttgaagct atagaaaaag ggtatattac cacttttata gaggcaggag cagcagtttc
    30121 tacaccaact tgtggtccat gtctaggggg acatatgggt atacttgcag caggagaaaa
    30181 atccatttca acaacaaata ggaatttcgt aggaagaatg gggcatgttg attcagaggt
    30241 gtatcttgca agcccagctg tagcagcagc atcagctata actggaaaaa tatcaaaacc
    30301 atcagaaata atttaaggga ggtaaaattt atgattgcca atggaagtgt ttttaaattc
    30361 ggtgacaata tagatacaga tgtaataata ccagctagat atttaaatat agctgattat
    30421 aaagaactag caacgcattg tatggaggat attgatgata aatttatttc taaggtaaaa
    30481 aaaggagata ttatagttgc aactaaaaac tttggttgtg gttcatcaag agaacatgca
    30541 ccaattgtaa taaaagaaag tggagtatcc tgtgtgattg cttctacttt tgctagaata
    30601 ttttttagaa actctataaa tatagggctt cctatacttg aatgtgaaga agctgccaat
    30661 aacatagatg aaggggataa tatagaagta gatttttcta caggtgtgat aaaaaatata
    30721 acaaaaggaa aagaatataa agcagaacca tttcctgagt ttatgcaaaa tattatatta
    30781 aatgaaggct taattaactc aataaaagca aatagggggt agtgaagtat gaattgtaat
    30841 atagcagtca taaaaggtga tggtgttgga ccggaaatta tagatgaagg tataaaggtt
    30901 ctaaataaaa tttgttgtaa atttaatcat agattcgatt gtgaatatgt attagctgga
    30961 ggatgcgcga ttgatgaaac tggagaacct ctacctaata aaactgttga aacttgtcga
    31021 aaaaacgaag ctgtattgct tggtgctgtt ggaggaccaa agtgggataa atgtaaggga
    31081 gataaaagac cagagtctgg tcttttaaaa ttaagagagt cattgggttt atttgcaaat
    31141 ttaagaccag ctacaatgta tgaaagtata aaagaagctt caccacttag aacggatata
    31201 gttgagaaag gcattgattt tgttgttgta agggaattaa cagggggcat ttattttgga
    31261 gaacgtggaa gaaaaatcat tgatggtatc gaaaatgctt atgatgtaga aatatataac
    31321 gaaaatgaaa taagaagaat tggtaagaga gcttttgaaa tagccagaaa tagaaataaa
    31381 aaacttataa gtgtagataa ggcaaatgtg cttgagagtt caagactttg gagaagtata
    31441 atggaagact tagctaaaga gtttgaagat gtagaactgt cacatatgta tgttgataat
    31501 gctgctatgc aagttgtaaa agaccctagc caatttgatg taatagtgac taataatata
    31561 tttggagata taatatctga tgaagcatct atgattacgg gttctatagg tatgttacca
    31621 tcagcatcac ttagagaaga tagttttggt atgtatgaac caatacatgg aagtgcacct
    31681 gatatagctg gaaaagatat tgtaaatcca attgcgacta ttctatctgt aagcatgatg
    31741 ttaagacata gttttaactt agaagaagaa gctaagtgta ttgaagatgc tgtacaaagt
    31801 gtactcaata aaggttatag aactattgat atctataatg gtgtgggaaa tgttgtagga
    31861 acaagggaaa tgggcgaatt aatagtaaat gaaatttaga attatagttt aatttgaata
    31921 atataattta aatatataac ttgtagaatt agtaaaaatc tattgtagta taatttgttt
    31981 tatgaggggt gtctcaaaat aaactttatt agttaatgag acactctttt ttatattaag
    32041 tcaaatatat ttttactatt ttaataacga aaaagaggtt tatatctact ttgagtttct
    32101 attttgataa agttattttt tggaaaataa tactttaaat taaacttatc atattgaagt
    32161 agcctatttt tattattaga agtttgcagg gattttatta atattatata atatatttta
    32221 gaattattta atattaagcg actactaatg tcggttagga gatggatttt ttggcaaagt
    32281 ataaagtttt gaagaagcaa aatagtagta aatcttgttt agtttgtgga acacaaaatg
    32341 agctaggact taaagcagat ttttatgaac ttgaaaatgg agagcttgta tcaatttgta
    32401 atacaaagga ttggcatcaa agttatcctg ggagagttca tggaggtatg tctgctgcaa
    32461 tattggatga gactattgga agagctgtaa gtataaatga tgaccaaata tggggagtaa
    32521 cagtatcttt agagttgaaa tataagaaac cagtaccaac agatgctact ataaaagttg
    32581 ttggaagaat aactaaagaa aacagaaaat tatttgaagg tacaggagaa ataattctac
    32641 caaatggaga tatagcagtg acagcaactg gaaagtatat gaaaatgcct attggacaaa
    32701 ttgcagaagg tgatttttct aatgaagaat ggttttttga agaatcgaaa gaaaaagtgg
    32761 aatatattga actttgatta aataaaaatt ttatatttta aaacataaat tttatattta
    32821 gaaaaaataa aattcaaaaa tacaataaaa atacaagata aaaataaatt agttatacta
    32881 aaaagattta tcgtaatagc gtaaaattta catactaaaa aaattaattt atatagataa
    32941 aaagtatatt ttttttgagg gaataattca gaaaattcag acttatgaaa aggtagaaaa
    33001 tgaatgtttt cataaaatat ataaaataaa ttatatataa aaaataaatt ttatgttgac
    33061 atagttaatt cagcttgata ttatagttat taaaaataag gacagtaaaa acgctatcca
    33121 tattacaaac taaaaagggg ggaattataa tgagtaagaa attatttatt cctggtccta
    33181 ttgatgttaa agaagaagtc ttgcaaaaga tggctacacc aatgatagga catagaggaa
    33241 aagatgcatc tatgctccaa aagagtataa gtgaaaagat gcaaaaacta ttctatacaa
    33301 acaacacgat acttttatcc acgtcatccg gaactggttt aatggaaggc tccattcgtt
    33361 cctgtacatc caaaaaggca gcagtatttt cctgtggatc ctttggtgat agatggtaca
    33421 aaatggcagt ggctaataat gtcccagcgg atatatttaa agttgaatta ggagaggcaa
    33481 caacgccaga aatggttgat aaggtgcttt ctaccggaga atacgattta ataactgtaa
    33541 ctcacaatga aacttcaact ggaataagaa atccaataga agaaattgga gaagttgtta
    33601 aaaagtatga ggatgtaatc tactgtgtag atactgtaag ttcagccggt ggaataaaag
    33661 tcgaggttga taagattgga atagatattt gtataacatc agtacaaaaa gcactgggat
    33721 taccaccagg aatgtctatt tgcacatttt ctcaaaaagc aatcgataga gctaagcaag
    33781 taccttttag aggagtatat cttgatttgt tagcaatgta tgaatactta atcaagaaaa
    33841 actaccaata cccttcaaca ccatctcttt ctcacatgtt cgctttagat ttccaattag
    33901 ataatatatt agatgaaggc ctagataaca gattcaacag acatgaagac atggcaaact
    33961 tagttagaaa ctgggctaaa aaacacttcc aaatttttac caatgaaaat cacttatcca
    34021 atacacttac tgttatagaa aatactcaag gtattagtgt atcaaattta aattcaaaat
    34081 tacaagaacg aggattccaa atagcaaatg gctatggaga tttaaaagaa aaaactttta
    34141 gaatttcaca tatgggtgac tatactgtcg aagatgtaca agaattatta gataatattg
    34201 atgatatatt aggttttaat aaataatatt gtaaaaatat gtatgtttta agataaa
//
LOCUS       DAYAOO010000039        33639 bp    DNA     linear   BCT 12-OCT-2024
DEFINITION  TPA_asm: Clostridioides difficile isolate ST8-SSI-h139-18
            SAMN40601845-rid21577343.denovo.039, whole genome shotgun sequence.
ACCESSION   DAYAOO010000039 DAYAOO010000000
VERSION     DAYAOO010000039.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN40601845
            Sequence Read Archive: SRR28438827
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 33639)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 33639)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-MAY-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-MAY-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002157583.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002157583.1
            Genome Coverage       :: 163x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/11/2024 16:19:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 4,038
            CDSs (total)                      :: 3,963
            Genes (coding)                    :: 3,930
            CDSs (with protein)               :: 3,930
            Genes (RNA)                       :: 75
            rRNAs                             :: 6, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 60
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 33
            CDSs (without protein)            :: 33
            Pseudo Genes (ambiguous residues) :: 0 of 33
            Pseudo Genes (frameshifted)       :: 7 of 33
            Pseudo Genes (incomplete)         :: 25 of 33
            Pseudo Genes (internal stop)      :: 11 of 33
            Pseudo Genes (multiple problems)  :: 8 of 33
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..33639
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN40601845-rid21577343.denovo.039"
                     /isolate="ST8-SSI-h139-18"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Denmark"
                     /collection_date="2018"
                     /collected_by="Statens Serum Institute"
     gene            224..1510
                     /locus_tag="ACGI5H_002093"
     CDS             224..1510
                     /locus_tag="ACGI5H_002093"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006439082.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine/sarcosine/betaine reductase component B
                     subunit"
                     /protein_id="HFG9697796.1"
                     /translation="MRLELGKIFIKDIQFGDVTEVKDGVLFINKQEMLQEIGGDEHIK
                     SIDIELARPGESVRITPVKDVIEPRVKVEGNGGIFPGIMSKVDTVGEGKTHALKGVAV
                     VTTGKIVGFQEGIIDMTGEGAKYTPFSKLNNVVVIAEPIDGLKQYAHEKAVRMIGFKA
                     AMYLGEVARNLTPDEVSVYETKPLLESIKEYPELPKVGYVYMLQTQGLLHDTYVYGVD
                     AKQIVPTLLYPTELMDGAIVSGNCVSACDKNPSYVHINNGVVEDLYARHGKDINFVGV
                     IITNENVYLADKERSSNWTSKLCKYLGLDAVIVSQEGFGNPDTDLIMNCKKIEMQGVK
                     TVIVTDEYAGRDGGSQSLADADVRADAVVTGGNANQVVVLPKLDKVIGHLEVVDVIAG
                     GSDGSLRADGTIEVEIQAITGATNETGFGHLTAKGY"
     gene            1622..2095
                     /gene="grdA"
                     /locus_tag="ACGI5H_002094"
     CDS             1622..2095
                     /gene="grdA"
                     /locus_tag="ACGI5H_002094"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_110943085.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0030700 - glycine reductase complex
                     [Evidence IEA];
                     GO_function: GO:0030699 - glycine reductase activity
                     [Evidence IEA];
                     GO_function: GO:0050485 - oxidoreductase activity, acting
                     on X-H and Y-H to form an X-Y bond, with a disulfide as
                     acceptor [Evidence IEA]"
                     /codon_start=1
                     /transl_except=(pos:1754..1756,aa:Sec)
                     /transl_table=11
                     /product="glycine/sarcosine/betaine reductase complex
                     selenoprotein A"
                     /protein_id="HFG9697797.1"
                     /translation="MSLLSNKKVLIIGDRDGIPGPAIEECVKTVEGAEVVFSSTECFV
                     UTAAGAMDLENQNRVKDAADKFGAENVVILLGAAEAEAAGLAAETVTAGDPTFAGPLA
                     GVALGLSVYHVVEEPIKSLFDESVYEDQISMMEMVLEVEEIEEEMSGIREEFCKF"
     gene            2127..3437
                     /gene="grdB"
                     /locus_tag="ACGI5H_002095"
     CDS             2127..3437
                     /gene="grdB"
                     /locus_tag="ACGI5H_002095"
                     /EC_number="1.21.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861534.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0030700 - glycine reductase complex
                     [Evidence IEA];
                     GO_function: GO:0030699 - glycine reductase activity
                     [Evidence IEA];
                     GO_function: GO:0050485 - oxidoreductase activity, acting
                     on X-H and Y-H to form an X-Y bond, with a disulfide as
                     acceptor [Evidence IEA]"
                     /codon_start=1
                     /transl_except=(pos:3174..3176,aa:Sec)
                     /transl_table=11
                     /product="glycine reductase complex selenoprotein B"
                     /protein_id="HFG9697798.1"
                     /translation="MGKLKAVHYINQFFAGIGGEEKADTKPHVAETLPPISLQLDKLL
                     GEDIEIVGTVVCGDSYFNENIDSASEEVLSMVKGFEPQLFIAGPAFNAGRYGVAAGTI
                     TKVVKDALNIPALTGMYVENPGADMFKKDVYVVETSDSAAGMRKALPKIAKLAVKLAN
                     GEEIGTPKDEGYIARGIRVNYFHEDRGSKRAVDMLVKKIKGEPFETEYPMPNFDRVDP
                     SKAVKDLSKCKIALVTSGGIVPKGNPDRIESSSASKYGTYSIAGVMDLTEETYETAHG
                     GYDPVYANLDADRVLPVDVLRDLEKEGVIGKLHETFYTTVGNGTSVANSKKYASEIGA
                     ALVADGVDAVILTSTUGTCTRCGATMVKEIEKTGLPVVHMCTVVPISLTVGANRIVPT
                     IAIPHPLGNPALDPTEEKALRRGLVEKALNALTTEVDGQTVFEK"
     gene            3693..5225
                     /gene="grdC"
                     /locus_tag="ACGI5H_002096"
     CDS             3693..5225
                     /gene="grdC"
                     /locus_tag="ACGI5H_002096"
                     /EC_number="1.21.4.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897537.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine/sarcosine/betaine reductase complex
                     component C subunit beta"
                     /protein_id="HFG9697799.1"
                     /translation="MTYPVLKGAGYVLIHTPDMIVQNGSTCTVERATNPDSEFLKEVS
                     NHIRSYEDVVNYMPNQVYIGNRRPEELRDLPMPWCEQKIEGTRNGKFGEIMPQDEFIA
                     LMQISDAFDLVKLSQEFIDEVKPKIENNYPEIAPFVGKLKGDDIEEGKELVATHIAEG
                     LYHDGKFVGYVKRAHDVDVNLNAHTMFENLVVKASGVLSAIQMLRHSKIDPAEIDYVI
                     ECSEEACGDINQRGGGNFAKSIAEIAGLQNATGSDTRGFCAAPTHALIQAAALVKAGI
                     HKNVMVVAGGASAKLGMNAKDHVKKGLPVLEDVVGGFAVLVSENDGVNPVIRTDLTGK
                     HTVGTGSSPQAVMTALITSGLDRANLKITDVDVYSVEMQNPDITKPAGAGDVPEANYK
                     MIGALAVKRGDLEKKELKDFVSNKGLPGWAPTQGHIPSGAPYIGFLIDDLTTGNRNRA
                     MIVGKGSLFLGRMTNLFDGVSFIAERNTGVTEETSGISKDEIKKIIAESMKKLALDML
                     EE"
     gene            5236..6381
                     /gene="grdD"
                     /locus_tag="ACGI5H_002097"
     CDS             5236..6381
                     /gene="grdD"
                     /locus_tag="ACGI5H_002097"
                     /EC_number="1.21.4.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903155.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine/sarcosine/betaine reductase complex
                     component C subunit alpha"
                     /protein_id="HFG9697800.1"
                     /translation="MSKKVIADVFLEVANAIESGEFGKKVKIGVTTLGSEHGVENMVN
                     GAQLAKSNLFDIVLIGPKVETDLEVVEVNDEKEMHAKMEELLDSGYIDACVTMHYNFP
                     IGVSTVGRVITPAKGKEMILATTTGTSATNRIEAMVRNAIYGIATAKSMGNKCPKVGI
                     LNVDGARQVEKCLKELKDNGYDMEFADSIRADGGCVMRGNDLLVGAPDVMVTDTLSGN
                     IFMKVFSSYTTGGDYEAQGFGYGPGVGEDYDRKVLIVSRASGSPVVANALKYAYDVVK
                     GDISNVARNEFAKVKKAKFDDIISSLTKKEVKAEKVEVKMPDKEIVTRQIAGVDIMDL
                     EDAVSELWKNGIYAESGMGCTGPIVLVNEAKGDLAVETLVKAGYTAK"
     gene            6691..7770
                     /locus_tag="ACGI5H_002098"
     CDS             6691..7770
                     /locus_tag="ACGI5H_002098"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430749.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008233 - peptidase activity [Evidence
                     IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="M24 family metallopeptidase"
                     /protein_id="HFG9697801.1"
                     /translation="MSRVKNVVELLETKGVDALYLTKKTNVNYISGFPDEEAYAVICK
                     DGNFLVTDSRYMELAEKVCKDFEIINWHNFDRSVAKAVKSVCDKVGIKKLGFERTNIV
                     FDKYEELKNLIEKDNGELIPTENIVETLRYVKDKDEIKNTRKACEIADKALEELIPHI
                     KAGVSEIELATKLEYFMKMNGAQNIGFETILISGAKTSLLHGKPSDKIIEKGDFVLID
                     YGAMYNGYISDTTRTFIVGGASEKQLEIYNLVKEAQNVGVENMKAGVHATIPDAEIRK
                     VVKKYEDYYYQGIGHGVGRDVHEEPFIGNYGDKIIEEGCIITMEPGIYFPGWGGVRIE
                     DTVLITKNGPERLTKFPKDLMILDK"
     gene            7883..8482
                     /locus_tag="ACGI5H_002099"
     CDS             7883..8482
                     /locus_tag="ACGI5H_002099"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903154.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9697802.1"
                     /translation="MYKKHKFIKNIKKAWYKIKLIDRCLIIVMAILMFQSIYNLFVNE
                     VNSQDTTTIDVVVRTTSAAIFGYFLSANFIKRPLRKYTNTDVSSNLFIDNNLSPKGQE
                     SNQNNIMNVKNTIGFTSEADNYEKKIPINNNEGFEEGETSELQIIIATVICIVALTVL
                     FVVRNFTTTTSASLGTISQMRDFVSGCVGFLLGCPSKPD"
     gene            complement(8668..9540)
                     /locus_tag="ACGI5H_002100"
     CDS             complement(8668..9540)
                     /locus_tag="ACGI5H_002100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893591.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HFG9697803.1"
                     /translation="MNINYLYYFQTVCKYKNMTKAAESIHISQPSITLAIKELEKELG
                     FELFYRIGNKIELTPEGKIFLDKSKHFIKQFEDFQCDALDLGKKRKASLKIGIPTVLG
                     TFLLSKILPRFNVIYPDIELKIFEVPTFVGAKMIEESTLDFCIGIIDSDIYDDIDSKT
                     IYKTELYLVTNPKNELAKHPIISNYMLKNVPFVILSEGSYHYKIITKRLEKAKPNIIL
                     HSNQLSTIRYLLENDLASTILYKEIFQNTENLCSIPLERAITANIGVLWRRNQYISHS
                     MKLFIEYMASIHIN"
     gene            9957..11360
                     /locus_tag="ACGI5H_002101"
     CDS             9957..11360
                     /locus_tag="ACGI5H_002101"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430743.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9697804.1"
                     /translation="MKGSDLVKFELMDFLMNPFVLMFAAVITGILFGKIKFGKFNFGV
                     SGALFTGLFIGWLAYSLGNLIIAKGETAAGYKAATVMMGNGIISSDFFDFFLIIFVAA
                     VGLLAAKDMKAVLKKYGARFVILGVLITFIGGSMTYAMTLLSSDKGSSAYEVSGVYTG
                     ALTSSPGLAAALETAGKHAEDVSKEFEKASIKDKKEILKVVDPEGKLDVNTTTSLTQE
                     QIDKYIAYAEAGVGIGHAVAYPFGVLIVILGVNFLPKLFRMDLKEERRKYEKEMKEAR
                     DSVSGKTIPEVPFNIITFFLTCLAGYLVGGIHVFMGPLGYFTLGATGGSLIVSLVLGY
                     IGKIGVVNFRMEEKVLNILKQIGLVFFLAIVGLRYGGKVVDSIMTSGMHLALVAIAVG
                     VTAMMIGFLVGKYVFKLNWILLSGAVCGGMTSTPGLGAAVDALDSDDPAAGYGATYPF
                     ALLTKVILVIVLHKLPM"
     gene            11387..12931
                     /locus_tag="ACGI5H_002102"
     CDS             11387..12931
                     /locus_tag="ACGI5H_002102"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861532.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA hydrolase/transferase family protein"
                     /protein_id="HFG9697805.1"
                     /translation="MNNEGAFEELSGRLRNKELCDLIMNADEAAKIIEDGMVIGVSGF
                     TPSGYPKAVPLAVSERAKSGEKIKLTVYSGASLGPEVDGAWSEAGIIERRLPYQTNSI
                     LRNNINKGVVDYIDMHLSHSTQFLNYGTIPKVDVAIVEALAITEEGNIIPTSGIGNSP
                     SFIKSADKVIVEINLAKPMEMEGMADIYITENPPNRKPIEINHPKDRIGTTYIPCGLD
                     KIAGVVITNMQDKTRPLGVVDEASKKISNNIIAFLREEVKAGRLSKNLLPLQSGVGSV
                     ANAVLYGLCESEFENLTCYTEVVQDSMLDLIRMGKVTMASTTSVSPSPEGLIKFEKDI
                     DFFKDKIILRPQEISNNPEIARRIGVIAMNTAIEVDIYGNVNSTHIMGSKMMNGIGGS
                     GDFARNGAITIFSTESIAKNGDISSIVPMVSHVDHTEHDVMVIVTEQGYADLRGLAPR
                     ERAIKIIENCAHPDYKEQLRDYLNRACKSGAKQTPHILDEALSWHSKFMSTGTMKKAE
                     TFKSAL"
     gene            12962..14353
                     /locus_tag="ACGI5H_002103"
     CDS             12962..14353
                     /locus_tag="ACGI5H_002103"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454646.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldehyde dehydrogenase family protein"
                     /protein_id="HFG9697806.1"
                     /translation="MEKAVENFEDLSKEYINGYIERARKAQREFECYTQEQVDKIVKI
                     VGKVVYYNAEYLAKLAVEETGMGVYEDKVAKNKSKAKVIYNNLKDKKSVGIIDIDRET
                     GITKVAKPVGVVAAITPCTNPIVTPMSNAMFALKGRNAIIITPHHKAIGCSTKTVEMI
                     NEELEKIGAPENLIQILDQQSRENTRNLISSADVVIATGGMGMVKAAYSSGKPALGVG
                     AGNVQCIIDRDVDIKEAVPKIIAGRIFDNGIICSGEQSVIVAEEMFDKIMDEFKNNKG
                     FIVRDKVQKEAFRNAMFVNKSMNKDAVGQSVHTIAKIAGVEIPEDTKIIVIEADGPGE
                     EDIIAKEKMCPVISAYKYKSFEEGVAIAKANLNVEGKGHSVSIHSNTVKNIEYAGENI
                     EVSRFVINQCCATSAGGSFFNGLAPTNTLGCGSWGNNSISENLDYKHLINISRIAYYM
                     PENEVPTDEELWG"
     gene            14546..16042
                     /gene="abfD"
                     /locus_tag="ACGI5H_002104"
     CDS             14546..16042
                     /gene="abfD"
                     /locus_tag="ACGI5H_002104"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430738.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-hydroxybutyryl-CoA
                     dehydratase/vinylacetyl-CoA-Delta-isomerase"
                     /protein_id="HFG9697807.1"
                     /translation="MALMTGAQYIESLRKLNTKVYMFGEEVKNWVDHPMIRPSINCVA
                     ATYDLAHDPEYADLMTVTSNITGEKINRFGHLHQSVDDLIKKVKMQRLCGQKTASCFQ
                     RCVGMDAFNAVYSTTFECDKAHGTNYHDNFVKYLTYIQENDLVVDGAMTDPKGDRSLS
                     PSAQPDPDMFLHIVERREDGIIVRGAKAHQTGSINSHEHLIMPTISMTEADKDYAVSF
                     AVPSDAEGVFMIYGRQSCDTRKLEEGADVDLGNKEFGGQEALVVFDNVFVPNDRIFLC
                     GEWDFSGMLVERFAGYHRQSYGGCKVGVGDVIIGAAALAADYNGANKASHIKDKLIEM
                     THLNESLYCCGIACSSEGHKTEAGNYQIDLLLANVCKQNVTRFPYEIVRLAEDIAGGL
                     MVTMPSEKDFKSDLKVGTSGMTIGEVCNKYFKASSVASTEERMRILRFLENICLGSSA
                     VGYRTESMHGAGSPQAQRIMISRQGNINQKKELAKKIAGIKKEEALNL"
     gene            16177..16452
                     /locus_tag="ACGI5H_002105"
     CDS             16177..16452
                     /locus_tag="ACGI5H_002105"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9697808.1"
                     /translation="MTCGVRFCGGCNPRYERGKALTIIKEHFNGRVDFSIAQENVEYD
                     LLLIIGGCATLCASYQQYKVKNECVKMWDFSHIERVINVIESAICET"
     gene            16476..17783
                     /locus_tag="ACGI5H_002106"
     CDS             16476..17783
                     /locus_tag="ACGI5H_002106"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454645.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA hydrolase/transferase C-terminal
                     domain-containing protein"
                     /protein_id="HFG9697809.1"
                     /translation="MSWQELYQSKLCSATEAVKQIKNGDTVVFAHCVGEPPALVEAMI
                     ENAEQYKDVEIKHMVSLGSGGYTAKGMEAHFRVNPMFVSGNVRKAIENGDGDFTPAFF
                     HEVPKLLREKRLKCDVVLAQVTPPDEHGYCSLGTSVDYTYEAIKTARTVIVQVNDQFP
                     RTYGEVVHVSEFDYIVEKSQPLFELQPAKIGEVEEAIGKNCASLIEDGSTLQLGIGGI
                     PDAVMLFLTDKKDLGIHSEMISDGTLALYEKGVINGKYKNFDKEKMTVTFLMGTKKLY
                     DFANNNPAVEVKPVDYVNHPAIIMKQHKMVSINSAIQVDLMGQVVAEAMGLRQFSGVG
                     GQVDFIRGVSMGEDGKAIIAMPSITTKKDGTVISKIVSIVDEGAPITTSRNDVDYIVT
                     EYGIAELKGKSLRERARNLINIAHPSVREHLAVEFEKRFKEKY"
     gene            17803..18921
                     /locus_tag="ACGI5H_002107"
     CDS             17803..18921
                     /locus_tag="ACGI5H_002107"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903149.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-hydroxybutyrate dehydrogenase"
                     /protein_id="HFG9697810.1"
                     /translation="MEALRVVPKIFYFDTFKEFNEEFKIGKNDLVITNEFIYEPYMKP
                     LGIDTNLIFQEKFGTGEPSDEMIDSMTKEMKKYNFDRIIAFGGGTIVDICKILALDVP
                     EKSIDLFEGEVSPKKVKELVVVPTTCGTGSEVTNVAIAELKSKHTKKGLAVEETYADY
                     AVLIPETVKGLPYKFFVTSSVDALIHAIESYLSPKASPFTEMYSLQAIKMIMDGYKKI
                     VDKGEEERFNHLRDFVLASNYAGIAFGNAGCAAVHALSYSIGGAFHVAHGEANYQFFT
                     EVFKMYSRKKPNGKIIKCTKILADALECDPNCDVYGELEKFLNKLIAKKALREYGMVE
                     SQIDEFTDSTIANQQRLLANNYVELSREEIREIFANLY"
     gene            19208..20128
                     /locus_tag="ACGI5H_002108"
     CDS             19208..20128
                     /locus_tag="ACGI5H_002108"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430730.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-bromo-4-chloroindolyl phosphate hydrolysis
                     family protein"
                     /protein_id="HFG9697811.1"
                     /translation="MYKSENFSKKSVLINSFLSKFLKIIGWGLVSLFTLSALVLSTIS
                     IIIGWAVILPIQVCAVFLLIGGVCIFKGKRLGDQISRYKKYCTIINNRNIIPVELIAE
                     NTSKSLNFIIKDVQKMIDKNYFINTYIDKRNNQIVLTNEDFVPPRYEDVAYEVKEEEK
                     TDESNEVDTIINKGMNYLTQIKEANKNIKSESMGDKIVQVEDVTSKIFDVVKHDPSKL
                     TQIQKFMDYYLPTTLKLLNSYHTLEEQGIDRENITTTMESIENTMNTIVVAFENQLDY
                     LFEDEAIDISTDITVLENMLVQEGLTSGKF"
     gene            20243..21400
                     /locus_tag="ACGI5H_002109"
     CDS             20243..21400
                     /locus_tag="ACGI5H_002109"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454642.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="toxic anion resistance protein"
                     /protein_id="HFG9697812.1"
                     /translation="MNNLDDIPVMPTLTLDPFGEESNTNDIDNSDLLMKKDEKDPEEE
                     KLSESERKMVKEFAEKIDITNTNMILQYGAGAQKKVASFSETALKSVKTRDLGEVGDM
                     LTNLVTDLKAFSADEKEQSGFLGIFKKANNKISNLKTKYDSAEVNVDKVSKELQKHQV
                     KILKDIAMLDKMYELNLAYSKELTMYIIAGKQKLKDMKEYEMPKLREKARLSGSTEDA
                     QSVNDMVSLCDRFEKKIHDLELTRMVSLQMAPQIRLVQNSNNLMAEKIQSTIVNTIPL
                     WKNQIVLALGISHLNQAMKAQREVSNMTNELLLKNAETLKMGTIETAKESERGIVDID
                     TIKKTNQSLISTIDEVVKIQHDGRIKRQEAEVELSKIENELKSKLLEFTVK"
     gene            complement(21485..22984)
                     /locus_tag="ACGI5H_002110"
     CDS             complement(21485..22984)
                     /locus_tag="ACGI5H_002110"
                     /EC_number="1.1.1.205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430726.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003938 - IMP dehydrogenase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="IMP dehydrogenase"
                     /protein_id="HFG9697813.1"
                     /translation="MAFYFDTPSHTFSEYLLVPGFSSTDCIPANVSLKTPVTKFKKGE
                     EADIYMNIPLTSAIMQSVSDDKMAIALAKEGGISFIYGSQTIENEAAMVARVKSHKAG
                     FVVSDSNIKPDNTLKDILDLKEKTGHSTVAVTEDGTSTGKLLGIVASRDYRISRMDLD
                     TKVSEFMTPMSSIVYANKDVTLKEANNIIWDHKLNSLPVLDDNGNLMYMVFRKDYSSH
                     KENPLELLDSSKRYVVGAGINTRDFAERVPALVEAGADVLCIDSSEGFSEWQKITLDF
                     IREKYGDTVKVGAGNVVDREGFLYLAEAGADFVKVGIGGGSICITREQKGIGRGQATS
                     IIEVAQARDEYFEKTGIYIPICSDGGIVYDHHITLALAMGADFIMLGRYFSRFDESPT
                     NKVNINGSYMKEYWGEGSARARNWQRYDLGGDKKLSFEEGVDSYVPYAGSLKDNVTLS
                     LSKVRSTMCNCGALSIPELQKNAKLTLVSSTSIVEGGAHDVMLKDNRNL"
     gene            23580..25004
                     /locus_tag="ACGI5H_002111"
     CDS             23580..25004
                     /locus_tag="ACGI5H_002111"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454640.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannitol transporter subunit IICB"
                     /protein_id="HFG9697814.1"
                     /translation="MSSSNQSTIKTSIQRVGKFLSGMVMPNIGAFIAWGLITALFIPT
                     GWMPNEKLSTIGDPMIKYLLPLLIAYTGGKAIAGQRGGVIGAAAAMGVIVGADIPMFI
                     GAMIMGPFAGWVIKKFDKFVDGKIPTGFEMLVNNFSIGIIGMLLAILGFYAIGPAIVA
                     GTALIESGVQFIVSKSLLPLVSVFIEPGKVLFLNNAINHGILGPIGIAEAKEAGKSIM
                     FLLESNPGPGLGVLLAYWMFSRGSVKQSAPGAVIIHFFGGIHEIYFPYILMNPVLILA
                     TMAGGAAGILTFSILGAGLVAAPSPGSIFALMALAPKGGLLPVLAGVAVATVVSFLVA
                     APFVKRASANQSEEDSTSLEEAKAKMSDMKSASKNSEKNIEEKQLEVNEIKKIVFACD
                     AGMGSSAMGASRFKNRIKNLDLNIEITNSSVDNLPDDTQIVVTHNTLVERVAKNNSSV
                     EIVSINNFLNDPNLDTLFKRLESK"
     gene            25030..27168
                     /locus_tag="ACGI5H_002112"
     CDS             25030..27168
                     /locus_tag="ACGI5H_002112"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454638.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antiterminator"
                     /protein_id="HFG9697815.1"
                     /translation="MDNLKKKKITSRQKKIILMIVANSKKNIPITISEIAGTLELSSR
                     TVLRDMSGIEKWFDENDFNFVKKPGVGLILEENIENQNFIIELLEEEKIEKEYSKEER
                     NLIILSKLLVSNEPVKSYYFAKILKVSEWVLNNDFALASKWLERFDIELVRKPGLGVY
                     LKGQEKNFREAYVNLIYDSFNEKEILDMVRNISENIQTDKAIEILSENRLLNLMDRCI
                     IRKVEATLTKKLSDLDVNLADSAYIGLVVHISLALQRIKNGENITMDKEFLKELSITE
                     EFKLAKEIVKGMETDFNMDIPVDEVGYITMHIRGAKQRSSSNHKALNLDDIEIMEITN
                     KMIDLAEDEFKISLKNDERLFKDLANHLGPSINRLNMGLEIRNPLLDEIKSKYSYAYD
                     VVEKISRIIKDKLNINSIPESEIGYIAMHFASAIEKNLMMNTNINIVVACPTGIGTSR
                     FLSTKIENKFPNLNILETISAINIDEEYLKEKDVDLIVSTVELNTSLNYICVGPFMSL
                     DDEQIIKEKIKSIAQNKLINLNAKNDTKSKNKVYEQITESMNIGKDILQFLEEIRFEK
                     FESKDLSELIEDSSKIFAKSSEDIISIKESLKERLKISIPYIEESKILLLHCMSERID
                     IMKLSIIKLENRIVLDSNEEIDNVVFMLLPKNSPSYQRQIMSEISGSLIDNIIFTNKI
                     NKFSIEEMALEVKDIVFNFYTNRLKAFIDK"
     gene            27198..27620
                     /locus_tag="ACGI5H_002113"
     CDS             27198..27620
                     /locus_tag="ACGI5H_002113"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430721.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:1902495 - transmembrane transporter
                     complex [Evidence IEA];
                     GO_function: GO:0016301 - kinase activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA];
                     GO_process: GO:0016310 - phosphorylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HFG9697816.1"
                     /translation="MSKVLNENNIFLGLDSVSKEEAITLAGRKLVENGYVKEEYIPAM
                     LEREKVMTTYMGMGVAIPHGVNEAKKEILSSGIVILQFPNGIDFDGEKAYLLIGIAGV
                     GDEHLEILSNIAVVLDDDLTERLKNSNDKQAFMEAFAN"
     gene            27639..28790
                     /locus_tag="ACGI5H_002114"
     CDS             27639..28790
                     /locus_tag="ACGI5H_002114"
                     /EC_number="1.1.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897524.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008926 - mannitol-1-phosphate
                     5-dehydrogenase activity [Evidence IEA];
                     GO_process: GO:0019594 - mannitol metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="mannitol-1-phosphate 5-dehydrogenase"
                     /protein_id="HFG9697817.1"
                     /translation="MKKAIQFGAGNIGRGFIGGLLVKSGYHVVFADVNEEILNSINKD
                     KKYTIHIRDVECIDEVIDNISAVSSIKEEIIDEIVQAEIITTAVGPLVLTKIASTIAK
                     GIKARKEKGLTSNLNIIACENAIYASSSLKEEVLKYLNKEEVEYLEMYVGFPNCSVDR
                     IVPPGKNENPLDVTVENFYEWNVEKQGFKGEIPTIVGMNLADNLMAYIERKLFTLNTG
                     HAITAYIGYLKGYKTIEESIKDKFICDIVKSAMVESGEGLIKKYNFDSEVHYKYIDKI
                     LNRFKNPYLNDDVLRVGREPLRKLSDKDRLIKPLMTAKSYGLSVDNLILGIGAALHYN
                     NSEDTQSVELQELIKSIGVKKAVAKIANISNDEELLNNIEKSYIFMKNL"
     regulatory      28896..28997
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00167"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="purine riboswitch; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="guanine and/or adenine"
                     /db_xref="RFAM:RF00167"
     gene            29180..29752
                     /locus_tag="ACGI5H_002115"
     CDS             29180..29752
                     /locus_tag="ACGI5H_002115"
                     /EC_number="2.4.2.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423114.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016763 - pentosyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0043101 - purine-containing compound
                     salvage [Evidence IEA];
                     GO_process: GO:0046110 - xanthine metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="xanthine phosphoribosyltransferase"
                     /protein_id="HFG9697818.1"
                     /translation="MKALQEKILREGSVSGNDILKVDSFLNHQIDVAFLNEIGREFKE
                     RFKGEKVDKIFTIEASGIAIASIVSQYFDNAPVVFAKKSESKNLDKDVYETNVYSFTK
                     AREYSVKVSKKYINKGENILIVDDFLANGRAALGLKDLIEQAEANLVGVGIVIEKGFQ
                     AGGALLKANDVRLESLAVVESIDNGTVKFR"
     gene            29816..30466
                     /gene="fsa"
                     /locus_tag="ACGI5H_002116"
     CDS             29816..30466
                     /gene="fsa"
                     /locus_tag="ACGI5H_002116"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423115.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016832 - aldehyde-lyase activity
                     [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="fructose-6-phosphate aldolase"
                     /protein_id="HFG9697819.1"
                     /translation="MRFFIDTANIEEIKEANDLGVICGVTTNPSLIAKEGRDFIEVVK
                     EISEIVDGPISAEVISLEHKGMIEEAEKLSKIHKNIVIKIPMTAEGLKAVKVLSSKGI
                     KTNVTLIFSAGQALLAARAGATYVSPFVGRLDDISQNGLDLIEEIVDIFSVNSIEAQI
                     IVASVRNPIHVLQAARMGADIATVPLKVINQMIKHPLTDKGIDSFMKDWEGASLKL"
     gene            30618..33542
                     /locus_tag="ACGI5H_002117"
     CDS             30618..33542
                     /locus_tag="ACGI5H_002117"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897518.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0008134 - transcription factor binding
                     [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sigma 54-interacting transcriptional regulator"
                     /protein_id="HFG9697820.1"
                     /translation="MDKILREIQREDKKNPYTDQELAEMLNVARSEVISVRKKNNILD
                     SRERRKKILIKDISKIVSENPQMSERKITEILIENGYNISRSAVSKLLKEENLNQSKI
                     GIKDKDPASSGKYVKVSKVVEEDGFEELIGIKGSLKEKVNLAKSAIMYPPNGLHTIIY
                     GETGVGKSELATCMYKYAIKNNIKEENSPFIVFNCADYAENPNLLIAQLFGVVKGAYT
                     GADANREGLVEQANNGILFLDEIHRLPAAGQEILFSLIDRGEFRRLGESSSNRKANVL
                     IISATTENPDSNLLQTFRRRIPMVINLPNMSERPKSERYEIIIKFFEREAKRVNKNFI
                     ITKEVMCALMNYKCTGNIGQLKSDIQVTCARAFSKSIFSSDKVIIDLDSLRDYIKSGY
                     YDCNCKNEKYSEFSVEDIYIDISELVSGKNRILSDNEISEIYNYAEKELKVLESKCFS
                     EEELKNAFIEKLDKKFNAIKNNKNLSDRRSRIDWGGQLKESTLEIMDKVIVFIKEQFK
                     HVNQGLYLALAIHIEHAIGRIKDGKTIINPSLDKIKASMPMEYELSRYIMGIVEDLTQ
                     VTFPEDELGYLAYYINKFCYNEESIKDKVKVVIVTHGKVGIEMSKVVNHILGIECTLG
                     IEIALTDSPSEGIEHVLEELQKIEARKGILVLIDMGSLVILGDEVEKRLGIRCKTVNR
                     VDTLLAMEAGKLATIEGKSLDGIIADLKKNKNYAMINTNKFSYRKNEYGKKNVIITLC
                     LSGVGTALNLKEHIEKQIKEYDTLIEVKPVAFLNNNLEEELNDIESEYNIIAICGTID
                     IDYKNVPFISYNEVLGKNGINKVLEHLNSKQPALNIENQLNNLIHEDLILYNFEGISK
                     EYIIDTLVSKLEEGGYVDSKYILSVYKREAMGSVVMASKVAVPHGLPENVMKPAIAIA
                     RLNKPIVWDNKFMVDLVVLLALKENNKKEIRSLFSKINDQHTLEVLLNTEDKNEIKEL
                     LS"
BASE COUNT        13229 a         3755 c         6328 g        10327 t
ORIGIN      
        1 ctgaagataa gaagaaaaag gtttttatgt ccaactttgt taaaaaaata attttaaata
       61 aaataatttt tttacaataa atatttttta gtaataaaat aaagatttaa ggcataaaaa
      121 cacaataata tatctttaaa aaaataagat aaattgtaaa atgatataat tttgagaaaa
      181 actcaaatgc atatacacaa attaaataac aggaggtgca agtatgcgtc ttgaattagg
      241 gaaaatcttt ataaaagata ttcaatttgg tgatgtaaca gaagtaaaag atggagtatt
      301 attcatcaat aagcaagaga tgctacaaga aattggtgga gatgagcata ttaaatctat
      361 agatatagaa ttagctcgtc caggtgaaag cgtaagaata acacctgtaa aagatgttat
      421 tgagccaaga gtaaaagttg aaggtaatgg gggaatcttc cctggtatca tgtctaaagt
      481 tgacactgta ggagaaggaa aaactcatgc tttaaaaggt gtagctgttg taactactgg
      541 aaaaatagta ggtttccaag aaggtataat agacatgact ggagaaggag ctaagtacac
      601 tccattttct aaattaaata atgtagtagt aatagctgaa cctattgatg gtttaaaaca
      661 atacgctcat gaaaaagctg ttagaatgat aggattcaaa gcagcaatgt acttaggaga
      721 agtagcaaga aatcttactc cagatgaagt ttcagtatat gaaactaaac ctcttcttga
      781 atcaataaaa gaatatccag agcttccaaa agtaggatat gtttacatgc ttcagactca
      841 aggtttatta catgatactt atgtatatgg agtagatgca aaacaaatag taccaacttt
      901 attatatcca acagaattaa tggacggagc aattgtaagt ggtaactgtg tttctgcatg
      961 tgacaaaaac ccaagttatg ttcatataaa caatggggtt gttgaagact tatatgcaag
     1021 acatggtaaa gatataaact ttgtaggtgt aattataact aatgaaaatg tttatctagc
     1081 agataaagaa agatcttcaa actggacttc taaattatgt aaatatttag gattagatgc
     1141 agttatagtt tcacaagaag gttttggaaa tcctgatact gaccttataa tgaactgtaa
     1201 gaagatagaa atgcaaggtg ttaaaacagt tatagttaca gatgaatatg ctggacgtga
     1261 tggaggttct caatcacttg cagatgcaga tgtaagagct gatgctgttg taacaggtgg
     1321 aaatgccaac caagttgtag ttcttcctaa gttagataaa gttattggac atttagaagt
     1381 agtagatgta atagctggtg gttctgatgg aagtttaaga gctgatggaa ctattgaagt
     1441 tgaaatccaa gctataacag gtgcaactaa tgaaacagga tttggtcatt taactgctaa
     1501 aggatattaa gaagtatttt attaaacgat tgagtaatgt taataaaaca tattatagat
     1561 aattataata agtgttatag atatataaaa atatattaga aatataataa ggaggattat
     1621 tatgagttta cttagtaata aaaaggttct tataataggt gaccgtgatg gtataccagg
     1681 acctgcgata gaagaatgtg taaaaacagt agaaggagca gaggttgttt tctcatctac
     1741 agaatgcttt gtctgaacag ctgctggggc tatggactta gaaaatcaaa acagagttaa
     1801 agatgctgct gataaattcg gagctgaaaa tgttgtgatt ttactaggtg ctgctgaagc
     1861 cgaagctgca ggtcttgcag ccgaaacagt aactgctgga gatccaactt tcgctggacc
     1921 acttgctgga gttgccttag gattaagtgt ttaccacgtt gttgaggaac caataaaatc
     1981 attatttgat gaaagtgtat atgaggacca aataagtatg atggaaatgg ttttagaagt
     2041 tgaagaaata gaagaagaaa tgtctggtat aagagaagaa ttttgtaaat tttaatgcct
     2101 aaaagcaaaa ggggtgaaac taagagatgg gaaaactaaa agcagtacat tatattaatc
     2161 agttctttgc tggtataggt ggagaagaaa aagctgatac taagccacat gtggcagaaa
     2221 ctttacctcc aataagttta caacttgata aattattagg tgaagatatt gaaatagttg
     2281 gaacagtagt ttgtggagat agctatttca atgaaaatat agatagtgca agtgaagaag
     2341 ttttatcaat ggtaaaaggt tttgaaccac aacttttcat agctggtcct gcatttaatg
     2401 ctggtagata tggggttgct gctggaacaa taactaaagt tgtaaaagat gctttgaata
     2461 taccagcttt aacaggtatg tatgttgaaa atccaggagc agatatgttc aaaaaggatg
     2521 tttatgtagt agaaacttct gattctgcag caggtatgag aaaggcactt cctaagatag
     2581 ctaaacttgc agtaaaactt gctaatggag aagaaattgg aactcctaaa gatgaaggat
     2641 acatagctag aggaataaga gttaactact tccatgaaga cagaggttct aagagagctg
     2701 ttgacatgtt agttaagaaa ataaaaggtg aaccatttga aactgaatac ccaatgccaa
     2761 actttgatag agttgaccca agtaaagctg taaaagattt atcaaaatgt aaaatagctt
     2821 tagttacttc tggtggtata gttccaaaag gaaatccaga tagaatagag tcttcttcag
     2881 cttctaaata tggaacttat tctatagcag gagttatgga tttaacagaa gagacttatg
     2941 aaactgcaca tggtggatat gacccagtgt atgcaaattt agatgcagat agagtattac
     3001 ctgttgatgt tcttagagat ttagaaaaag aaggtgtaat tggaaaatta catgagactt
     3061 tctatacaac tgtaggtaat ggtacatctg ttgcaaactc taaaaaatat gcttctgaaa
     3121 ttggagcagc attagtggct gatggtgtag atgcagtaat attaacttct acatgaggta
     3181 cttgtactcg ttgcggtgca acgatggtaa aagaaataga aaaaactgga cttccagtag
     3241 ttcatatgtg tacagtagta cctatttcat taacagtagg ggctaataga atagttccaa
     3301 ctatagcaat acctcatcca cttggaaatc cagcgcttga ccctacagaa gaaaaagccc
     3361 taagaagagg ccttgtagaa aaagcattaa atgctttaac tacagaagta gatggtcaaa
     3421 cagtatttga aaaataaaaa taacacacac atatattata tagataaaaa tataaacaca
     3481 cactaaaaat aaaaaataac tatacacaaa aaaataatat agatttcatg aatggataaa
     3541 ttggagttat tcattcatga aatcttaaaa aatgccaaaa tacataaaca ataatagaat
     3601 caaatataca ataaaataca atgattagag cttttaataa gtttaataag attaaaaaat
     3661 aagtgttcat aaaatttatg gaggtgcaca aaatgactta tccagtttta aaaggggcag
     3721 gctatgtact tattcatact ccagatatga tagtgcaaaa tggaagtact tgtacagttg
     3781 aaagagcaac aaatccagat tcagaatttt taaaagaagt aagtaatcat ataagaagtt
     3841 atgaagatgt agttaactac atgccaaatc aagtttatat aggaaataga agaccagaag
     3901 aattaagaga tttaccaatg ccatggtgtg aacaaaagat tgagggaact agaaatggta
     3961 agtttggaga aataatgcct caagatgagt tcatagcttt aatgcaaata agtgatgcat
     4021 ttgatttagt aaaattatca caagaattta ttgatgaagt aaagccaaaa atcgaaaata
     4081 actaccctga aattgcacca tttgtaggta aattaaaggg tgatgatata gaagaaggta
     4141 aagaattagt agcaacacac atagctgaag gattatacca tgatggaaaa tttgttggtt
     4201 atgtaaaaag agcacatgat gtagatgtta acttaaatgc ccatacaatg tttgaaaatc
     4261 tagtagtaaa agcatctgga gttttatctg ctattcaaat gctaagacat agcaaaatag
     4321 accctgctga aatagattat gttattgagt gttcagaaga agcttgtgga gatataaacc
     4381 aaagaggtgg aggaaacttt gctaaatcaa tagctgagat agcaggactt caaaatgcaa
     4441 ctggttctga cacaagagga ttttgtgcag caccaactca tgcattaatt caagcagcag
     4501 ctttagtaaa agctggtata cataaaaatg taatggtagt agcaggtgga gcaagtgcta
     4561 aacttggaat gaatgctaaa gaccatgtta aaaaaggtct tcctgtactt gaagatgttg
     4621 ttggaggatt tgcagtactt gtatctgaaa atgatggtgt aaatccagtt ataagaactg
     4681 atttaacagg taagcatact gttggaactg gttcttcacc acaagcagtt atgacagcac
     4741 ttataacttc aggtcttgat agagctaatt taaaaataac agatgttgat gtgtattcag
     4801 ttgaaatgca aaacccagat ataactaagc cagcaggagc aggagatgtt ccagaagcaa
     4861 actacaaaat gataggggca cttgctgtta aacgtggaga cttagaaaag aaagaattga
     4921 aagattttgt ttctaacaaa ggattaccag gatgggcacc aactcaagga catataccat
     4981 caggagctcc ttatatagga tttttaatag atgatttaac tacaggaaat agaaatagag
     5041 ctatgatagt tggaaaaggt agtttattct taggaagaat gactaactta tttgatggag
     5101 tatcttttat agctgaaaga aatacaggtg ttactgaaga gacttcagga atatctaagg
     5161 atgaaattaa gaagataata gctgaatcta tgaaaaaact agcattagat atgttagaag
     5221 aataggggtg aggatatgtc aaaaaaagta atcgcagatg tattcttaga agtagctaat
     5281 gcaatagaaa gcggcgaatt tggcaaaaaa gtaaaaattg gtgttactac acttggaagt
     5341 gaacatggtg tagaaaacat ggttaatggt gcacaattag caaaatctaa tttatttgat
     5401 attgtgctta ttggaccaaa agtggaaact gaccttgaag tagttgaagt taatgatgaa
     5461 aaagaaatgc atgcaaaaat ggaagaatta ttagattcag gatatattga tgcttgtgtt
     5521 actatgcatt ataattttcc aataggtgta tctacagtag gtagagtaat aactccagca
     5581 aaaggaaaag aaatgatact tgcaacaaca acaggaacaa gtgctactaa tagaatagag
     5641 gcaatggtaa gaaatgccat ttatggtatt gctacagcta aatcaatggg taacaaatgc
     5701 ccaaaagttg gaatacttaa tgttgatgga gcaagacaag ttgagaagtg cttaaaagaa
     5761 ttaaaagata atggatatga catggagttt gcggattcaa ttagagcaga tggtggatgt
     5821 gtaatgagag gtaatgattt acttgtaggt gcacctgatg ttatggttac tgatacatta
     5881 tctggaaata tatttatgaa agtattttct tcatatacta caggtggaga ttatgaagct
     5941 caaggctttg gatacggacc tggagttgga gaggactatg atagaaaggt acttatagta
     6001 tcaagagcat caggttctcc ggtagtagca aatgctttaa aatacgctta tgatgttgta
     6061 aagggagata taagtaatgt tgcaagaaat gaatttgcaa aggttaaaaa agcaaaattt
     6121 gatgacatta tatcctctct tactaaaaaa gaagttaaag ctgaaaaagt agaagttaaa
     6181 atgccagata aagaaattgt tactcgtcaa atagctggtg ttgatataat ggatttagaa
     6241 gatgcagtat ctgagttatg gaaaaacgga atctatgctg aaagtggtat gggttgtaca
     6301 ggtccaatag ttttagtaaa tgaagctaaa ggagacttag cagttgaaac tttagttaaa
     6361 gctggatata ctgcaaaata agtacatttt ttatatgtaa ataagaacat atagttataa
     6421 ttttattgat tataattata tgttcttttt attttatatc ttgtcaatat ttatatatta
     6481 acacaatcca tttatttgat tctctagcta atttattata tttattcagt taaaattaag
     6541 ctttctaact aaataaaaac taatgaagta ttaaaatgaa attgataaaa tatgaaaaaa
     6601 ttttaggaat aaagtatctg ttagataaaa ataagattaa ttagtgatat aatataatta
     6661 agataaaatt tattatttgg aggcaaaatc atgagcagag taaaaaatgt agtagaattg
     6721 ttggaaacta aaggtgttga tgcactatat ctaacaaaga aaactaatgt aaactatata
     6781 agtggttttc ctgatgaaga agcatatgca gtgatttgca aagatggaaa ctttttagtt
     6841 actgatagta gatatatgga gcttgcagaa aaggtttgca aagattttga aattataaat
     6901 tggcataatt ttgatagaag tgtggcaaag gcagttaaaa gtgtatgtga taaagtgggt
     6961 ataaagaaac ttgggtttga aagaactaat atagtgtttg ataaatatga agaacttaaa
     7021 aatctgattg agaaggataa tggagaatta atacctacag aaaatattgt agagactttg
     7081 agatatgtaa aagacaaaga tgaaatcaaa aatacaagaa aagcttgtga aatagcggat
     7141 aaggcattag aagaattgat tccacatata aaagctggag ttagcgaaat tgaactggct
     7201 acaaagttag agtactttat gaaaatgaac ggagcacaaa atatagggtt tgaaactata
     7261 ctgatatcag gagcaaagac ttcattgctt catggtaagc ctagtgataa gattatagaa
     7321 aaaggtgatt ttgtacttat agactatggc gctatgtata atggctatat atctgataca
     7381 actagaactt ttatagttgg aggagcttct gaaaagcaat tagaaatata taatttagtt
     7441 aaggaagctc aaaatgtagg ggttgagaac atgaaagctg gtgtacatgc gacaattcca
     7501 gatgctgaga taagaaaagt tgtcaaaaaa tatgaagact attactatca aggtatagga
     7561 catggagtcg gtagagatgt tcatgaagaa cctttcattg gtaattatgg tgataaaatc
     7621 atagaagagg gatgtataat aacaatggaa ccaggtattt atttccctgg atggggtgga
     7681 gttagaatag aagatactgt tttgattact aaaaatggtc cagaaagact tactaaattc
     7741 cctaaagatt tgatgatttt agacaaataa tttaatttat atatattttt ttacataaaa
     7801 tataacataa tctcactatt aagctctatt tacatattat agtaaagagg gcttaatttt
     7861 attgtgagag gtgatagtat atatgtataa aaaacataaa tttataaaaa atataaaaaa
     7921 agcctggtat aaaatcaaat taattgatag atgccttata attgtaatgg caatattaat
     7981 gtttcaatct atatataatt tatttgttaa tgaagtaaat tcacaagata ctacaactat
     8041 tgatgtagta gtaagaacca cttcagcagc tatatttggg tattttttaa gtgctaattt
     8101 tataaagaga cctttaagga agtatacaaa tactgatgta tcttcaaatc tttttataga
     8161 taataattta tccccaaaag gtcaagagtc taatcaaaat aatataatga atgtcaaaaa
     8221 taccattgga tttacttcag aagctgataa ttatgaaaag aaaataccta ttaataataa
     8281 tgaaggtttt gaagaaggag aaactagtga attgcaaatt attatagcta ctgtaatttg
     8341 tatagtagca ttaacagtac tttttgttgt aagaaatttt acaactacaa catcagcttc
     8401 tttaggtact atttcacaga tgagagattt tgtctcagga tgcgtgggtt ttttgctagg
     8461 ttgtccaagt aaacctgatt aaaaaagtat tatcaataaa aggtatttta aaaagtatca
     8521 gtataataat atttagattt aaatgtatac aattataatt ctaaacattc tatattgtat
     8581 ttttatactg atactctaaa ctatactatt tattaaaata ttttaacatt gtatttaaac
     8641 aaaatattat atctgtataa tataaattta gtttatatga atagatgcca tatactcaat
     8701 aaaaagtttc atactatgag atatgtattg atttcttctc caaagaaccc caatattcgc
     8761 agtaattgca cgttctaatg gtattgaaca gagattttct gtattttgaa atatttcttt
     8821 atacaatatt gttgaagcca agtcattttc tagtaaataa cgtatggtag aaagttgatt
     8881 tgagtgtaaa attatatttg gcttagcttt ttcaagtctt tttgtaataa tcttatagtg
     8941 ataagaacct tcagataaga ttacaaaagg tacatttttt aacatataat tcgatataat
     9001 gggatgtttt gccaattcat ttttgggatt tgtaactaag tataattctg ttttatagat
     9061 tgtctttgaa tctatatcat cataaatatc actgtcaatt ataccaatac aaaaatcaag
     9121 tgtagattct tcaatcattt tagctccaac aaatgttgga acttcaaaaa ttttaagctc
     9181 tatatctgga taaattacat taaatctagg aagtattttt gaaagcaaaa acgtacctaa
     9241 aactgtagga atacctattt tgagagaagc ttttctcttt tttcctaaat caagtgcgtc
     9301 acattgaaaa tcctcaaatt gttttataaa atgttttgac ttgtctaaaa aaatttttcc
     9361 ttcaggcgtt aactctattt tattacctat tctgtaaaaa agttcaaagc caagttcttt
     9421 ttctaattct ttaattgcta atgttatgga tggttgagaa atatgaatac tttccgcagc
     9481 cttagtcatg tttttatatt tacagacagt ttgaaaatag tataaatagt ttatattcat
     9541 ttggtattag ttcctttcat ttacatatta gtgacaagta tataattaac aatagcataa
     9601 gttttgtata ttgttgtaaa aaaatagaat agttttaaac tatcatagca taagtttttg
     9661 atattttcaa tctattaaga atagtgctat tattaaatta acaaaagaga atagctggta
     9721 tggtttagag taaatcaatc tatattacag ttatatcaac gaatatcaaa aaattatcta
     9781 ttagaaaata aaaattattt ttacaattaa attgttaatt aaatcataaa gaaaaaagtg
     9841 atattaacaa gataaaattt ttttaatcag aaatgttaat ttaataacaa aatagagtat
     9901 tggggagaaa ggagaaatat attttttaat aatatttgtt aatttaataa cgaaaaatga
     9961 aagggagtga tttagtgaag tttgaattga tggatttttt aatgaatcct tttgtcctta
    10021 tgtttgctgc agtaattaca ggaattttat ttggaaaaat taaatttggg aagtttaatt
    10081 ttggggtatc aggagcatta tttacaggat tatttattgg atggcttgca tatagcttgg
    10141 ggaatctaat aatagcaaaa ggggaaacag cagcaggata taaggcagca actgtaatga
    10201 tgggtaatgg aattatttct tctgacttct ttgatttctt tttaataata tttgttgcag
    10261 cagttggtct attggcagca aaagatatga aagctgtatt aaagaagtat ggagcaagat
    10321 ttgtaatttt aggagttctt ataactttta taggtggctc tatgacttat gcaatgactt
    10381 tactatcaag tgataaagga agtagtgctt atgaagtttc tggcgtttac acaggagcat
    10441 taacaagttc gcctggatta gctgctgctt tagaaacagc tggtaaacat gcagaagatg
    10501 tatcaaaaga atttgaaaaa gcttcaataa aagataaaaa agaaatttta aaagtagtcg
    10561 acccagaagg caaattggat gtgaatacaa ctacatcact gactcaagag caaatagata
    10621 agtatattgc atatgctgaa gctggtgttg gtataggtca tgcagtcgca tatccttttg
    10681 gagttttaat agtaatctta ggtgtaaatt tccttccaaa attatttagg atggacctaa
    10741 aagaagaaag aagaaaatat gagaaggaaa tgaaggaagc aagagatagt gtttctggta
    10801 aaacgatacc agaagttcca tttaatataa taacattttt cttgacatgt ttagctggat
    10861 acttagttgg aggaatacat gtatttatgg gaccactagg gtacttcaca ctaggcgcaa
    10921 caggaggttc actaattgta tctctagttc ttggatatat aggtaagata ggggtagtaa
    10981 atttcagaat ggaagaaaag gttttaaata ttttaaaaca aatagggcta gtatttttct
    11041 tagcaatagt tggattaaga tatggtggaa aagtagttga ttcaattatg acatctggta
    11101 tgcacctagc cttagtagca atagcagtag gtgttacagc tatgatgata ggattcttag
    11161 ttggcaaata cgtatttaaa ttaaattgga ttttattatc tggagctgtc tgtggtggta
    11221 tgacatcaac accaggtctt ggagctgctg ttgatgctct tgatagtgat gacccagcag
    11281 caggttatgg tgctacgtat ccatttgcat tattaactaa agttatattg gttatagttt
    11341 tacacaaact tccaatgtaa ataagatttt atatgggggg atatttatga ataatgaagg
    11401 agcatttgaa gaattaagtg gaagattaag aaataaagaa ttgtgtgatt taataatgaa
    11461 tgcagatgaa gctgctaaaa ttatagagga tggcatggtt attggagtta gtggatttac
    11521 accttcaggc tatccaaaag cagtaccatt agcagtttca gaaagagcta aaagtggaga
    11581 aaagataaaa ttaaccgtat attcaggagc atctttaggt ccagaagttg atggagcatg
    11641 gtcagaagca ggtataattg aaagaagact tccttatcaa actaattcaa tacttagaaa
    11701 taatattaat aaaggtgttg ttgattatat agatatgcac ctaagtcatt ctactcaatt
    11761 tttaaattat ggaactatac ctaaagtaga tgtagctata gtagaagcac ttgcaataac
    11821 tgaagaagga aatattatac caactagtgg gataggtaat tctccatctt ttataaaaag
    11881 tgcagataaa gtaatagtag agataaatct tgcaaaacca atggaaatgg aaggtatggc
    11941 agatatatat attacggaaa atccaccaaa tagaaaacca atagaaataa atcatcctaa
    12001 ggatagaatt ggaacaacat atataccttg tggtttggat aaaattgcag gagtagtaat
    12061 taccaatatg caagataaga cccgtccatt gggagttgta gatgaagctt cgaaaaaaat
    12121 atcaaataat attattgctt ttttaagaga agaagtaaag gcaggcagat tatcaaagaa
    12181 tttacttcct cttcaatctg gtgtaggaag tgtagcaaat gcagtattat atggattatg
    12241 tgaatctgaa tttgaaaatt taacttgtta tacagaggtt gtacaggact ctatgttgga
    12301 tttaataaga atgggtaaag ttacaatggc atctactaca tctgtaagtc catctccaga
    12361 aggattaata aaatttgaaa aagatattga tttttttaag gataagatta tattaagacc
    12421 tcaagaaatt agtaacaatc cagaaatagc cagaagaatt ggtgtaattg caatgaacac
    12481 tgcaattgaa gttgatattt atggaaatgt aaattctact cacataatgg ggtcaaagat
    12541 gatgaatgga attggtggtt ctggtgattt tgctagaaat ggagcaataa ctatatttag
    12601 tactgagtca attgcaaaaa atggtgatat atcatcaata gtacctatgg tatctcacgt
    12661 agaccacact gaacatgatg taatggtaat tgtaacagaa caaggatatg ctgatttaag
    12721 aggtcttgca cctagagaaa gagctataaa aataatagaa aattgtgccc atccagatta
    12781 taaagaacaa cttagggatt atttaaatag agcttgtaaa agtggagcaa aacaaacacc
    12841 tcacatattg gacgaagctt tatcatggca tagtaaattt atgagtacag gtacaatgaa
    12901 aaaggctgaa acttttaaaa gtgcattata aaatatttaa taaattggag gtagatttta
    12961 aatggaaaaa gcagtggaaa actttgaaga tttaagtaag gaatacatta atggttatat
    13021 tgagagagca agaaaagctc aaagagagtt tgaatgttat actcaagaac aagtagataa
    13081 aatagtaaaa atagttggaa aagtagtgta ttataatgct gaatatttag ctaaacttgc
    13141 tgtagaagag actggaatgg gagtatatga agataaggta gctaaaaata aaagcaaagc
    13201 aaaagttata tataacaatt taaaagataa aaaatcagtt ggtataattg atatagatag
    13261 agaaactgga ataacaaagg tagctaaacc agttggagta gtagcggcaa taactccttg
    13321 tacaaatcca atcgttacac ctatgagcaa tgcaatgttt gcacttaagg gaagaaatgc
    13381 aattattatc acacctcatc ataaagcaat tggatgtagt acaaaaactg tagagatgat
    13441 taatgaagaa ttagaaaaaa taggagctcc agaaaattta atacaaatac ttgaccaaca
    13501 atcaagagaa aatacaagaa atttaatttc atcagcagat gtagtaattg ccactggagg
    13561 aatgggaatg gtaaaagctg cgtactcaag tggaaaacca gcacttggtg taggggcagg
    13621 aaatgttcaa tgtatcatag atagagatgt agatattaaa gaagcagtac ctaaaatcat
    13681 agcaggaaga atttttgata atggtatcat ttgttcaggt gaacagtcag taatagtagc
    13741 agaagaaatg tttgataaaa taatggatga atttaaaaat aataaaggtt ttatagttag
    13801 agataaagta caaaaagaag ctttcagaaa tgctatgttt gtaaataaat ctatgaataa
    13861 agatgcagta ggtcaatcag ttcatacaat tgcaaaaatt gcaggtgttg agataccaga
    13921 agatacaaaa ataatagtaa tagaagctga tggaccagga gaagaggata ttattgcaaa
    13981 agaaaaaatg tgtccagtta tatctgcata caagtataaa agttttgaag aaggtgtagc
    14041 tattgcaaaa gcaaatttaa atgtagaagg aaaaggacat agtgtatcta tacattcaaa
    14101 tacagttaaa aatatagaat atgcaggaga aaatatagaa gtatcaagat ttgttattaa
    14161 tcaatgttgt gctactagtg ctggaggaag tttctttaat ggtcttgcac ctactaatac
    14221 tctaggttgt ggttcttggg gaaataacag catctctgaa aatcttgatt ataagcatct
    14281 aattaatatt tctagaattg cttattatat gccagaaaat gaagtcccta cagatgaaga
    14341 actttgggga taaaatttag acaaaaaata ttcattctaa attaaagtag gaatatattt
    14401 taatttagaa tgaatttaag acataaatta aatttaaatt agtttattgg actaaattta
    14461 aaatattaag agacatatag aagaaggaag tattataatt taaaataaat aaaaaaatct
    14521 ataaaagaga aggagtggtt ttattatggc attaatgaca ggagctcaat atattgaaag
    14581 tttgagaaaa ttaaatacta aggtttatat gtttggtgaa gaggttaaga attgggttga
    14641 ccatcctatg attagaccat ctataaattg tgtagcagca acttatgact tagctcatga
    14701 cccagaatat gcagatttaa tgacagttac ttcaaatatc acaggtgaaa aaataaatag
    14761 atttggtcat cttcatcaaa gtgttgatga tttgataaaa aaagtaaaaa tgcaaagact
    14821 atgtggtcaa aaaacagctt cttgtttcca aagatgtgtt ggtatggatg cgtttaatgc
    14881 agtgtattca acaacatttg agtgtgataa agcccatgga actaattatc atgataattt
    14941 tgtaaaatac ttaacttata tacaagaaaa cgatttagta gttgatggag ctatgactga
    15001 ccctaaggga gatagaagtc tatcacctag tgctcaacct gacccagata tgttccttca
    15061 tatagtagaa agaagagaag atgggataat tgtaagagga gcaaaggcac atcaaactgg
    15121 ttcaataaat tcacatgagc accttataat gcctactata agtatgactg aagcagataa
    15181 agactacgct gtatcatttg cagttccttc agatgctgaa ggagtgttta tgatttatgg
    15241 aagacaatct tgtgacacta gaaaattaga agaaggtgca gatgttgatt taggaaataa
    15301 ggagtttgga ggtcaagaag ctttagtagt atttgataat gtatttgttc caaatgatag
    15361 aattttctta tgtggagaat gggatttctc tggtatgtta gtagagagat ttgcaggata
    15421 ccatagacaa agttatggtg gatgtaaagt aggagtaggt gatgtaataa taggagcagc
    15481 agctttagca gctgattata atggagcaaa caaagcttca catataaaag ataaactaat
    15541 agaaatgact caccttaatg aaagcttata ttgctgtggt atagcatgtt catcagaagg
    15601 tcacaaaaca gaagctggaa actatcaaat agatttactt cttgcaaatg tgtgtaaaca
    15661 aaatgtaact agatttcctt atgaaatagt aagacttgca gaagatatag ctggagggct
    15721 tatggttact atgccttcag aaaaagactt taaatcagac cttaaagttg gaacaagtgg
    15781 aatgactatt ggcgaagtat gtaacaagta ttttaaagct tcttcagtgg cttcaacaga
    15841 agaaagaatg agaatattaa gattcttaga aaatatatgc cttggttcat ctgctgttgg
    15901 ttatagaact gagtcaatgc atggggcagg ttcaccacaa gctcaaagaa taatgatttc
    15961 aagacaagga aacataaatc aaaagaaaga attagctaag aaaattgcgg gaataaaaaa
    16021 agaggaagct ttaaatttat aaaaagttga tatataaagg gaaattatat attaatgtgt
    16081 gttaattaat gaaaaaatat gtagtataag agatagttat aaaattatgg tggtttttag
    16141 ctaagtaaag aaatttttaa taaggagaat ttacacatga cctgtggagt tagattttgt
    16201 gggggctgta accctagata cgaaagaggg aaggctctta caataatcaa agagcacttc
    16261 aatggtaggg tagattttag tatagcacaa gagaacgtcg agtatgattt gttacttata
    16321 attggaggat gcgcaactct atgcgcatcc tatcaacaat ataaagtgaa aaatgaatgt
    16381 gttaagatgt gggattttag ccatatagaa agagttataa atgtgattga atcagcaatt
    16441 tgtgaaactt aaaaaagcta aatgggggga tttcattgag ttggcaagaa ttgtatcaaa
    16501 gtaaattatg tagtgctaca gaagctgtaa aacagattaa aaacggtgat actgtagtat
    16561 ttgcacattg tgtaggtgaa cctcctgcac tagtagaagc tatgattgaa aatgctgaac
    16621 aatataaaga tgttgagatt aaacatatgg taagcttggg tagtggtgga tatactgcta
    16681 agggaatgga agctcatttt agagtaaatc caatgtttgt aagtggaaat gtaagaaagg
    16741 caattgaaaa tggagatggt gattttacac ctgcattctt ccatgaagta ccaaagttgc
    16801 ttagagaaaa aagattaaaa tgtgatgttg ttttagcaca ggtaactcca ccagatgaac
    16861 atgggtattg tagcttagga acatcagttg attatactta tgaagccatt aaaactgcta
    16921 gaacagtaat tgttcaagtg aatgaccagt ttcctagaac ctatggtgag gtagtccatg
    16981 tatcagagtt tgactatata gtggaaaaat cacaaccttt atttgaacta caacctgcaa
    17041 agattggaga agtagaagaa gcaattggta aaaattgtgc ttcattaatt gaagatggct
    17101 ctactttaca gctagggatt ggtgggatac cagatgcagt tatgttattt ttaactgata
    17161 aaaaggattt agggattcat tcagaaatga tttcagatgg gactttggcc ctttatgaaa
    17221 aaggtgttat aaatggtaaa tataaaaatt ttgataaaga aaaaatgaca gttaccttct
    17281 taatgggtac taaaaaatta tatgactttg caaataataa ccctgcagta gaggtaaaac
    17341 cagtagacta tgtgaatcat ccagcaatta taatgaaaca acataagatg gtttctataa
    17401 attctgctat acaagttgat ttaatgggac aggtagttgc agaggctatg ggacttagac
    17461 aatttagtgg tgttggaggt caagttgact ttatacgtgg agtgtctatg ggtgaagatg
    17521 gaaaggcaat tatagctatg ccttcaataa ctacaaaaaa agatggtaca gtaatttcaa
    17581 aaatcgtatc tattgtggat gaaggtgcac ctataacgac atcaagaaat gatgttgact
    17641 atattgtaac agaatacggt atagcagaat taaaaggaaa atctcttaga gaaagagcaa
    17701 gaaatttaat aaatatagct catccaagtg taagagaaca tctagcagta gaatttgaaa
    17761 agagatttaa ggagaaatat taataataga ggggtgttaa taatggaagc acttagagta
    17821 gttccaaaga tattttactt tgatacattt aaagaattta atgaagaatt taaaatagga
    17881 aaaaatgatt tagtaattac taatgagttt atatatgagc catatatgaa acctcttgga
    17941 atagatacaa atttaatttt tcaagaaaag tttggaacag gtgaaccatc tgatgaaatg
    18001 atagactcca tgacaaagga aatgaagaaa tacaattttg atagaattat tgcatttgga
    18061 ggaggaacaa tagttgatat atgtaagata ttagcacttg atgttccaga aaagtctatt
    18121 gatttatttg aaggagaagt atcacctaaa aaagtaaaag agttagtagt agttcctaca
    18181 acatgtggta caggtagtga agtaacaaat gtagctattg cagagttaaa atctaaacat
    18241 actaaaaagg ggcttgcagt agaagaaaca tatgcagact atgcagtgtt aattccagag
    18301 acagtaaaag ggttacctta caaattcttt gttacaagtt cggtagatgc tcttatacat
    18361 gctattgagt cttatctttc tccaaaagca agtccattta cagagatgta ttctctacaa
    18421 gcaataaaaa tgattatgga tgggtataag aagatagttg ataaaggaga agaagagaga
    18481 tttaatcatc ttagagactt tgtacttgca tcaaattatg caggaattgc ttttggaaat
    18541 gctggttgtg cagcagttca tgcactatct tattcaatag gtggagcttt ccatgttgca
    18601 catggtgaag caaattatca gttctttact gaagtattta agatgtattc tagaaaaaaa
    18661 cctaatggaa aaattataaa atgtacaaaa attttagcag atgcccttga atgtgaccct
    18721 aactgtgatg tttatggaga attagaaaag tttttaaata aattaatagc taaaaaagct
    18781 ttgagagaat atggaatggt ggaaagtcag atagatgaat ttacagatag tacaatagca
    18841 aatcaacaac gactacttgc taataattat gtagagctta gtagagagga aataagagag
    18901 atatttgcaa atctttatta atacaatttt ttatttatat gtatagtcaa cataaacaat
    18961 gctaattata tttatgtaca aataaaaata agggaactta aattttaatt aaagttaagt
    19021 tctcttattt ttatatggag ttaaatataa gtatattttt aatttaaaat atgcttatat
    19081 ttaagtctat tactttattt gaaacaattt gtagaatttc aaattccttg acagtaataa
    19141 gtaagtaatt gtataatcaa actgcaatat attaataata ttagtgaaaa tgaaaggatt
    19201 ataaaatatg tataaatcag aaaatttttc aaaaaaatct gtattaataa attcattttt
    19261 aagtaaattt ttaaaaataa ttggatgggg tttggtaagc ttatttacat tatcagcctt
    19321 agtactttca actatttcca ttataattgg atgggctgta atacttccta ttcaagtatg
    19381 tgcagtattt ttacttatag gaggagtttg tatttttaaa ggtaagagat taggagacca
    19441 aatttctcgt tataaaaaat attgtacaat tataaacaat agaaatatta ttccagtaga
    19501 acttattgca gaaaacacat ctaaatcatt aaattttata ataaaagatg tacaaaagat
    19561 gatagacaaa aactacttta taaatactta tattgataaa agaaataatc agattgtgtt
    19621 aacaaatgaa gattttgttc caccaagata tgaagatgta gcatatgaag tcaaagaaga
    19681 agaaaagact gatgaatcca atgaagttga tacaattata aataaaggaa tgaattatct
    19741 aacacaaata aaagaagcta ataaaaatat taaatcagaa tcaatgggcg ataaaattgt
    19801 acaagtagaa gatgttacaa gtaaaatatt tgatgttgta aaacatgacc catcaaaact
    19861 tactcagata caaaaattta tggattatta tcttccaacc actttaaaac tattaaattc
    19921 atatcataca ttggaagaac aaggaattga tagagaaaat ataacaacaa ctatggaaag
    19981 tattgaaaat acaatgaata cgattgtagt agcttttgaa aatcaattgg actatctgtt
    20041 tgaagatgaa gccattgata tttctacaga tattactgtt ttagagaata tgttagtcca
    20101 agaaggatta acgagtggta aattttaact tcaatagaaa aaatattctg ttatttttaa
    20161 acaattaatt agtcataaag tataaaatgt gtattatata agttaatcag tactttatga
    20221 aggaagagga gagaaagata caatgaataa tttagatgat ataccagtta tgccaacttt
    20281 gacacttgac ccatttggag aagaatcaaa cactaatgat atagataatt ctgacttatt
    20341 aatgaaaaag gatgaaaaag acccagaaga agaaaaactg tctgaatctg aacgcaagat
    20401 ggtaaaggaa tttgcggaaa aaatagatat tacaaataca aatatgattt tgcaatatgg
    20461 agctggagct caaaaaaagg tagcaagttt ttctgaaaca gctttaaaga gtgtaaaaac
    20521 aagagattta ggagaagttg gagatatgct tacaaatcta gttactgatt taaaagcatt
    20581 ttcagcagat gaaaaagaac aaagtggttt tttaggaatt tttaaaaagg caaataataa
    20641 aatttcaaat ttaaaaacta agtatgatag tgcagaggta aatgtggata aagtaagcaa
    20701 agagcttcaa aagcatcagg ttaaaatatt gaaagatata gcaatgcttg ataagatgta
    20761 tgaattgaac ttagcttact caaaagagct tactatgtat attatagcag gaaaacaaaa
    20821 attaaaggat atgaaagaat atgaaatgcc aaagttgaga gaaaaagctc gtttatctgg
    20881 ttcaacagaa gatgctcaat ctgtaaatga tatggtttca ctttgtgaca gatttgaaaa
    20941 gaagattcat gacttagaat taactagaat ggtatcgctt caaatggctc ctcagataag
    21001 attggttcaa aatagtaata atctgatggc agaaaagatt caatcaacta tagtaaatac
    21061 cattccatta tggaaaaatc aaatagtgct tgctcttgga atttctcact taaatcaagc
    21121 tatgaaagca cagcgtgaag ttagtaatat gacaaatgag cttttattaa agaatgcaga
    21181 aactttgaag atgggaacaa tagaaacagc aaaagaatca gaaagaggaa ttgtagatat
    21241 agacacaatt aagaaaacta atcaatctct aatatctact attgatgagg tagttaaaat
    21301 acaacatgat ggtagaataa agagacaaga agcagaagtt gaattatcaa aaatagaaaa
    21361 tgaacttaaa agtaagcttc ttgaatttac agttaaataa aaattatact aatataaaaa
    21421 gagactgtct caaaatagag ataagtctct ttttcattgt ttaaatgatt aaagtatatt
    21481 tatattataa atttctatta tcttttaaca taacatcatg agctccacct tcaactatac
    21541 tagtagaaga tacaagtgta agtttagcat ttttttgaag ttcaggaatg ctaagtgctc
    21601 cacagttaca catagtagaa cgaactttac ttaaagaaag agttacattg tctttcaaag
    21661 aaccagcata aggcacataa gagtcaacac cttcttcaaa agaaagtttc ttatctccac
    21721 caaggtcata tctttgccag tttctagcac gagcagaacc ttctccccaa tactctttca
    21781 tataactacc atttatatta actttgttag ttggactctc atcaaaacga gagaagtatc
    21841 taccaagcat tataaaatct gcacccatag ctaaagctaa agttatatga tggtcataaa
    21901 cgataccacc atcagagcaa attggaatat aaatacctgt tttttcaaag tattcgtctc
    21961 tagcttgagc aacttcaatt atagaagtag cttgtccacg tcctatacct ttttgttcac
    22021 gagttataca tatagaacca ccaccaatac caactttaac gaagtcagca ccagcttcag
    22081 ctaggtaaag gaatccttcg cggtcaacta catttccagc tcctacctta actgtatcac
    22141 catatttttc acgaatgaaa tcaagtgtta ttttttgcca ctcagaaaaa ccttctgaag
    22201 aatctataca taaaacatca gcaccagctt caactaaagc aggaacacgt tcagcaaagt
    22261 ctctagtatt aataccagct ccaactacat atctcttaga agaatctaaa agttcaagtg
    22321 gattttcttt atgagaagag taatctttac ggaataccat atacataaga ttaccattat
    22381 catcaagtac aggaagagaa ttaagtttgt ggtcccatat aatattgttt gcttccttta
    22441 aagtaacatc tttgttagca taaactatag atgacatagg agtcataaat tcactaactt
    22501 tagtatctaa atccatacga cttatacgat aatcacgact tgcaacaata cccaataatt
    22561 taccagttga agttccatct tcagtaacag ctactgtaga atgtccagtt ttttctttta
    22621 agtcaagtat gtcttttaat gtgttatcag gtttaatatt tgaatcactt acaacaaaac
    22681 cagctttgtg ggatttaaca cgtgctacca tagcagcttc attttcaata gtttgagaac
    22741 cgtatataaa tgaaatacca ccttctttag caagtgcaat agccattttg tcatcagaaa
    22801 cagattgcat aatagcagaa gtcaaaggta tattcatata aatatctgct tcctcgccct
    22861 ttttaaattt agtaacaggt gtttttaaac ttacattagc aggtatacaa tcagtagaag
    22921 agaaacctgg tacaagaagg tattcactga aagtatgtga tggtgtatca aaataaaacg
    22981 ccatttttta atcactcctt atatttttat actttttata attgatagta ttaattataa
    23041 cttattcttt aattttatta aagtattttg tcaaatattg agatttttga aaaatttaaa
    23101 ctattttaat taaatttgtt taatatatat tgccttatag ggtaaagttg tatattaaat
    23161 aatgtttagt gtttaatagt agctaattta aaattaatct ttagtgattc atataattac
    23221 atttgtatag tttacattga taatattact agagagtgca taaacctcaa aaatacagat
    23281 aaattaaatc tatattagta tatccaaaag tacatttaat aaatttattt aactgaatta
    23341 ttattttcat ttctattaaa tttaaatatt ttataaaaat agtattattt acaaaatcat
    23401 atactccaaa atactacata aataaaatta aacaaaaact aaaatgacaa atgtcattat
    23461 ctaaagtgac atagaaacgg tttcttaaag ttgttactat aaaatataaa ctctataata
    23521 aaagtataac aaaagggaat catatcgata tagaatataa ttcaagagga ggtaaaatta
    23581 tgagtagttc taatcaatcg acaataaaga catctataca gcgagtaggg aaatttttaa
    23641 gtggtatggt aatgccaaat ataggagctt ttatagcatg gggtcttata acagcattat
    23701 ttataccaac aggatggatg cctaatgaaa aattgagtac tataggtgac ccaatgataa
    23761 aatacctttt accactattg atagcttata ctggtggtaa agcaatagca ggacaaagag
    23821 gtggcgtaat aggtgcagca gcagctatgg gagtaattgt tggtgcagat ataccaatgt
    23881 ttattggagc aatgataatg ggaccatttg caggatgggt aattaagaag tttgataaat
    23941 ttgtagatgg aaagatacca acaggatttg aaatgttagt aaataacttt tcaataggta
    24001 taataggtat gcttcttgca atactaggat tttatgcaat tggaccagca atagtagcag
    24061 ggacagctct tatagaatct ggagttcaat ttatagttag caaaagttta ttgcctctag
    24121 tttcagtatt tatagaacct ggaaaagtat tattcttaaa caatgcaata aatcatggta
    24181 tattagggcc tataggtata gctgaggcaa aagaagcagg taaatctata atgttcttac
    24241 tagaaagtaa ccctggacca ggtttaggag ttctattagc atattggatg tttagtagag
    24301 gaagtgtaaa acaatcagca ccaggagctg taataataca tttctttggt ggtatccatg
    24361 aaatttactt cccatatatt ttaatgaatc cagttttaat attggctaca atggcaggtg
    24421 gagcagcagg aatattgact ttttcaatat taggagctgg gcttgtagca gcaccatcac
    24481 caggaagtat atttgcactt atggcactag ctccaaaggg aggattactt ccagtattag
    24541 caggagttgc agtggcaaca gttgtatcat tcttagtggc agcaccattt gttaagagag
    24601 cttcagcaaa tcaaagtgaa gaagacagta cttctttaga agaagctaaa gcaaaaatga
    24661 gtgatatgaa atctgcaagt aagaactctg agaaaaatat tgaggaaaaa cagcttgaag
    24721 taaatgagat taagaagatt gtatttgcat gtgatgcagg aatgggttcg agtgcaatgg
    24781 gagcttccag atttaaaaat agaataaaaa acttagactt aaatatagaa attacaaatt
    24841 catctgttga taatcttcca gatgatacac aaatagtagt aactcacaat acattagttg
    24901 aaagagttgc taagaataat tcaagtgttg agatagtttc aataaacaat tttttaaatg
    24961 acccaaattt agatacattg tttaaaagat tagaatctaa ataaaaataa aaagtaccac
    25021 taattaggag tggataattt gaaaaaaaag aagattacat ctaggcaaaa aaagataata
    25081 ctaatgatag tagcaaattc aaagaaaaac attccaataa ctatttctga gattgcaggg
    25141 actttagagt taagttcaag aactgtactt agagatatgt ctggaattga aaaatggttt
    25201 gatgaaaatg attttaactt tgtaaaaaaa ccaggagtgg gattgatttt agaggaaaat
    25261 atagaaaatc aaaactttat aattgagttg ttagaagaag aaaaaataga aaaagaatac
    25321 agcaaggaag aaagaaattt aattatatta tcaaagctac tagtttctaa cgagccagta
    25381 aaatcctatt attttgcaaa aatattaaag gtatctgaat gggtactgaa taatgatttt
    25441 gccttagcaa gtaaatggtt ggaaagattt gatattgagc ttgttagaaa accagggctc
    25501 ggtgtctact taaaaggtca agaaaaaaac tttagagagg catatgtaaa tcttatatac
    25561 gattcattca atgaaaaaga aatactagat atggtcagaa atataagtga aaatatacaa
    25621 acagataaag caatagaaat tttaagtgaa aatagacttt taaatttaat ggacaggtgc
    25681 ataataagaa aagttgaagc tacattaaca aagaagcttt cagatttaga tgtaaattta
    25741 gctgatagtg catatatagg gcttgtagtt catatttcat tagccttaca gaggataaaa
    25801 aatggtgaaa atataactat ggataaagag tttctaaaag aattatctat aacagaagag
    25861 tttaaattag ctaaagaaat cgtaaaaggt atggaaacag attttaacat ggatatacca
    25921 gtagatgagg ttggatatat aactatgcat ataagaggtg caaagcaaag gtcatcttca
    25981 aaccataagg ctttaaactt agatgatata gaaataatgg aaattacaaa taagatgata
    26041 gatttggcgg aagatgaatt taaaataagt ttaaaaaatg acgagaggtt atttaaagac
    26101 ctagcaaatc acttagggcc ttctataaat aggttgaata tgggattaga aataagaaat
    26161 cctcttttag atgaaataaa aagcaagtat tcatatgcct atgatgtagt tgaaaagatt
    26221 tctagaatta taaaagataa actaaatata aattcaatac ctgaatcaga aataggatat
    26281 attgcaatgc actttgcatc agccatagaa aaaaatctta tgatgaatac taatataaat
    26341 attgttgtgg catgtcccac tggaataggt acttcaagat tcttatcaac taagattgaa
    26401 aataaatttc ctaatttaaa tatacttgaa accatatcag ctataaacat agatgaagag
    26461 tatttaaagg aaaaagatgt tgatttaata gtgtctacag ttgagttaaa tacaagttta
    26521 aattatatat gtgtaggtcc atttatgagt ttagatgatg aacagataat caaggaaaaa
    26581 ataaaatcta tagctcaaaa taaattaatc aatttaaatg cgaaaaatga tactaagagt
    26641 aagaataaag tatatgaaca gataacagaa agtatgaata taggaaaaga tattcttcaa
    26701 tttttagagg aaattagatt tgaaaaattt gaaagtaaag atttaagtga gcttattgaa
    26761 gactcatcaa aaatatttgc aaaatctagt gaagatataa tctctataaa agaatcgtta
    26821 aaagaaagat taaaaatttc aattccatat atagaagaat caaaaattct attgttacat
    26881 tgtatgagtg aaagaataga tattatgaag ttatcaataa taaaactaga gaatagaatc
    26941 gtgctagatt caaatgaaga aatcgacaat gtagttttta tgttacttcc taaaaattca
    27001 ccaagttatc aaagacaaat aatgagtgaa ataagtggtt cattaataga caatataatt
    27061 tttactaata agataaataa attctctata gaagagatgg cattagaggt aaaagatata
    27121 gtttttaatt tttatacaaa cagattaaaa gcatttatag ataaataaaa ttaatattaa
    27181 aaaggaaggt tgatactatg agtaaagtat tgaatgagaa taatatattt ttagggttag
    27241 atagtgtttc aaaggaagaa gctataactt tagcaggaag aaaattagtt gaaaatggat
    27301 atgtaaaaga agaatatata ccagcaatgt tagaaagaga aaaagtaatg actacatata
    27361 tgggaatggg agttgctatt ccacatggtg taaatgaagc aaaaaaagaa atattatctt
    27421 ctggaatagt tatattacaa ttccctaatg gtatagattt tgatggagaa aaagcatatt
    27481 tattaatagg aatagctggt gttggagatg aacatttaga aatactatct aatatagcag
    27541 tagttttaga tgatgactta acagaaagac taaaaaattc aaatgacaaa caagctttta
    27601 tggaagcttt tgccaactaa tcttaggagg gatttaaaat gaaaaaggca attcagtttg
    27661 gagcaggaaa tattggaaga ggttttattg gaggcttgtt agttaagtcg ggttatcatg
    27721 tagtatttgc tgatgtaaat gaggagatat taaactcaat aaacaaagat aaaaagtata
    27781 ctatacacat aagagatgta gaatgtatag atgaagtaat tgataatata agtgcggttt
    27841 catctataaa agaagaaata atagatgaga ttgtacaggc tgaaataata actacagcag
    27901 ttggaccttt agttttgact aaaatagcct ctacaattgc aaaaggtata aaggctagaa
    27961 aagaaaaggg attaacaagt aatctaaata taatagcatg tgaaaatgca atatacgcaa
    28021 gttcttcttt aaaagaagag gtacttaagt atttaaataa ggaagaagta gaatatttag
    28081 agatgtatgt tggttttcca aactgttcag ttgatagaat agttcctcct ggtaaaaacg
    28141 aaaatcctct tgatgtaaca gttgaaaatt tttatgagtg gaatgttgaa aaacaaggat
    28201 ttaaagggga aataccaact atagttggta tgaatttagc tgataatctt atggcttata
    28261 tagaacgtaa attgtttaca ctgaatacag gtcatgctat aacagcttat ataggatatt
    28321 taaaaggata taagactata gaagagagta taaaagataa atttatctgt gatatagtca
    28381 aaagtgcaat ggtagaaagt ggagaaggat tgattaaaaa atacaatttt gactcagaag
    28441 tgcactataa atatattgat aaaattttaa atagatttaa aaatccatat cttaatgatg
    28501 atgtattaag agtcggaagg gaaccattaa gaaaactaag tgataaagat agattgatta
    28561 aacctttaat gacagcaaaa tcatatggat tatcagttga taatttgatt cttggaatag
    28621 gtgcagcgct tcattataat aatagtgaag atactcaaag tgtagaatta caagagttga
    28681 taaagtctat tggagtaaaa aaagccgttg ctaaaatagc taatataagc aatgacgaag
    28741 aacttttaaa caatatcgaa aaaagttata tatttatgaa aaatttataa atttacttga
    28801 aaaaaagtag ttctgataaa gtaactataa tatattattc tacacagttt gaattatttg
    28861 ttgaataata gagaattata atatataatt aaaaggaata aattaatata tttacctgta
    28921 tatgtttgat aatatggttc aaatgtttct actaagctac cattaatagc ttgactacag
    28981 gagtgaagaa gatatagttt atacttattt taaattatat attaagttaa ttactttgaa
    29041 ttttaagctc ctgtctatga tatagacagg agctttttta gtattttaat ataaaatact
    29101 tacaagaata gatagcaaaa ttagaacaaa tataattttt ttattaatat aattttagaa
    29161 agggctaggt ggaagttcaa tgaaggcttt acaagaaaag atattgagag aaggcagtgt
    29221 ttcaggaaat gatatactaa aagttgatag ttttttaaac catcaaattg atgtagcttt
    29281 tttaaatgaa ataggaagag aatttaaaga gagatttaaa ggagaaaagg tggataagat
    29341 atttacaata gaggcttcag gaatagctat agcatcaatt gtttcacagt attttgataa
    29401 tgcacctgta gtatttgcaa aaaaatcaga atctaaaaat ttggataaag atgtatatga
    29461 aactaatgta tattcattta ctaaggcaag agagtattca gttaaagttt ctaaaaagta
    29521 cataaacaaa ggcgaaaata tattgatagt ggatgatttt ttggcaaatg gaagagctgc
    29581 tcttggactt aaagatttaa ttgagcaagc agaagctaac ttagttggag taggaattgt
    29641 cattgaaaaa ggatttcaag ctggaggagc acttttaaag gctaatgatg taagattaga
    29701 gtctttggca gtagttgaat ctatagataa tggaactgta aaatttaggt aatttatgat
    29761 attatatact tgtgtttagc acatatttta actatgtaat tatggaggat tttttatgag
    29821 attttttata gacacagcca atattgaaga aataaaagaa gcaaatgatt taggtgtaat
    29881 ctgtggtgta actactaatc cgtctctaat agctaaagaa ggtagagatt ttatagaggt
    29941 agttaaagaa ataagtgaaa tagtagatgg accaataagt gcagaagtaa taagtttaga
    30001 acataaaggt atgatagagg aagcagaaaa attatctaag atacataaaa atatagttat
    30061 aaagatacct atgacagcag aaggtctaaa agcggtgaaa gtactatcaa gtaaaggtat
    30121 aaagactaat gtaacgctta tattctctgc tggacaagct cttttagctg ctagagctgg
    30181 agctacatat gtaagtcctt ttgttggtag attggatgat atatcacaaa atggtcttga
    30241 tttaattgaa gaaatcgttg atatatttag tgtaaatagt attgaggctc aaataatagt
    30301 tgctagtgtt agaaatccaa tacatgtttt acaagctgct agaatgggag cagatatagc
    30361 aacagttcct cttaaagtta taaaccaaat gattaagcat cctttgacag acaaaggaat
    30421 agatagcttt atgaaggatt gggaaggtgc ttctttaaaa ttataattat aaactacgct
    30481 ttataagtat attaaagagg ttattatgga aattctaagt aataaggcta ggctattttg
    30541 cctagtctta ttttggtgta taatatattg aaacatatta ttgaaataga ttaatttttt
    30601 aagtgaggag gcgaaaaatg gataaaatat taagagagat acaaagagaa gataaaaaaa
    30661 atccatatac tgaccaagaa cttgctgaaa tgttaaatgt agctaggtct gaagtgatat
    30721 cagttaggaa aaaaaataat attttagatt cgagagaaag aagaaaaaaa atattaataa
    30781 aagatatatc aaaaattgta agtgaaaatc ctcaaatgtc tgaaagaaaa ataactgaaa
    30841 tattaataga aaatggatat aatatatcga gaagtgcagt ttcaaaatta ttaaaagagg
    30901 aaaatttaaa tcagtcaaag attgggatta aggataaaga cccagcatca tcaggaaagt
    30961 atgtgaaggt gagtaaagtt gtagaagaag atggatttga agaattgata ggtataaagg
    31021 gaagtttgaa agaaaaggta aatctagcta agtcagcaat aatgtatcct cctaatggcc
    31081 ttcatactat aatatatgga gaaacaggag taggtaaaag tgaattagct acatgtatgt
    31141 ataaatatgc tataaaaaac aacattaaag aagagaacag cccatttata gtgtttaact
    31201 gtgcagacta tgcagaaaat cctaatctat tgatagctca actctttggg gtagtaaaag
    31261 gtgcatatac aggagcagat gcaaatagag aaggtcttgt agaacaagct aataatggaa
    31321 tattgttttt agatgaaatt catagattgc ctgctgctgg gcaagaaatc ttattttcat
    31381 taatagatag aggagaattt agaaggttag gagaaagtag ttctaataga aaggcaaatg
    31441 ttctcataat aagtgctaca acagaaaatc cagattctaa tttacttcaa acatttagaa
    31501 gacgtatacc aatggtaata aatttaccta atatgagtga aagaccaaaa tctgaaagat
    31561 atgaaataat aataaagttt tttgaaagag aagcaaagcg agtaaacaag aattttataa
    31621 taactaaaga agttatgtgt gcacttatga attataagtg tactggaaat ataggtcagt
    31681 taaagagtga tatacaagta acttgtgcta gagcttttag taaatcgata ttttctagcg
    31741 ataaagtaat tatagattta gatagtttaa gggattatat aaaaagtgga tattatgatt
    31801 gtaattgtaa aaatgaaaag tattctgagt tttcagttga ggatatatat atagatatta
    31861 gtgaattggt gagtggaaaa aatagaattt tatctgataa tgagataagc gagatatata
    31921 attatgcaga aaaagagctt aaggttttgg aaagtaagtg cttttcagaa gaagagttaa
    31981 aaaatgcatt tatagaaaag ttagataaga agtttaatgc tattaaaaac aataaaaatt
    32041 tatctgatag aagaagtcga atagactggg gaggacaatt aaaagagtct acactggaga
    32101 taatggataa ggtaattgta tttattaagg agcagtttaa gcatgtaaat caaggtctgt
    32161 acttggctct agcaattcat attgagcatg ctataggtag gataaaagat ggaaaaacta
    32221 taataaatcc gagtttagat aaaataaaag catcaatgcc aatggaatat gagttgtcaa
    32281 gatatataat gggtatagta gaagatttga cacaagtaac atttccagaa gatgagcttg
    32341 gatatttggc ttattatata aataaatttt gttataatga ggaaagtata aaagataaag
    32401 ttaaagtagt aatagttacg catggtaaag ttggaattga aatgtctaaa gttgtaaatc
    32461 atattttagg tatagaatgt acactaggta tagaaatagc acttacagat tcaccatcag
    32521 aggggataga gcatgtatta gaagaacttc aaaagataga agctagaaaa ggtattctag
    32581 ttctaattga tatgggttct ttggtaattc ttggtgatga ggttgaaaaa aggcttggaa
    32641 ttagatgtaa aactgtaaat agagtagata cattattggc aatggaagca ggaaaacttg
    32701 caacaattga aggaaaaagt ttagatggta taatagctga tttaaagaaa aataagaatt
    32761 atgctatgat aaatacaaat aaatttagtt acagaaaaaa cgagtatgga aagaaaaatg
    32821 taatcattac tttatgtttg agtggtgtag gtacagcttt aaatttaaaa gagcatatag
    32881 aaaaacaaat taaggaatat gacactttaa ttgaagtaaa gccagttgct tttttaaata
    32941 ataatttaga agaagagtta aatgatattg aatctgaata taatattatt gctatctgtg
    33001 gaactattga tatagattat aaaaacgtgc cttttatttc ttataatgag gtacttggta
    33061 aaaatggtat taataaagta ttagagcatt taaatagtaa acaaccagct ttaaatattg
    33121 aaaaccagtt gaataattta atacatgaag atttgatttt atacaatttt gaaggaattt
    33181 caaaggagta tataattgat actcttgttt caaaacttga agaaggtgga tatgttgact
    33241 caaagtatat attaagtgta tataaaagag aagcaatggg aagtgttgta atggcctcta
    33301 aggtagccgt gccacatgga cttccagaaa acgttatgaa gcctgcaata gcaatcgcga
    33361 ggttgaataa acctatagta tgggacaata aatttatggt ggatttggtg gtactactgg
    33421 cacttaaaga aaataataag aaagaaatac gaagcttatt ttcaaagatt aatgaccagc
    33481 atactttaga agttttatta aatactgaag ataaaaatga aataaaagaa cttttaagct
    33541 aattattagt accgagaaga aagacaaaaa aatttgcttt agtataaaat ttaaaactac
    33601 tcaattgcta agtagttaat tactctatat aaggctagt
//
LOCUS       DAYAOO010000040        33486 bp    DNA     linear   BCT 12-OCT-2024
DEFINITION  TPA_asm: Clostridioides difficile isolate ST8-SSI-h139-18
            SAMN40601845-rid21577343.denovo.040, whole genome shotgun sequence.
ACCESSION   DAYAOO010000040 DAYAOO010000000
VERSION     DAYAOO010000040.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN40601845
            Sequence Read Archive: SRR28438827
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 33486)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 33486)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-MAY-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-MAY-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002157583.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002157583.1
            Genome Coverage       :: 163x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/11/2024 16:19:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 4,038
            CDSs (total)                      :: 3,963
            Genes (coding)                    :: 3,930
            CDSs (with protein)               :: 3,930
            Genes (RNA)                       :: 75
            rRNAs                             :: 6, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 60
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 33
            CDSs (without protein)            :: 33
            Pseudo Genes (ambiguous residues) :: 0 of 33
            Pseudo Genes (frameshifted)       :: 7 of 33
            Pseudo Genes (incomplete)         :: 25 of 33
            Pseudo Genes (internal stop)      :: 11 of 33
            Pseudo Genes (multiple problems)  :: 8 of 33
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..33486
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN40601845-rid21577343.denovo.040"
                     /isolate="ST8-SSI-h139-18"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Denmark"
                     /collection_date="2018"
                     /collected_by="Statens Serum Institute"
     gene            753..1661
                     /gene="trxB"
                     /locus_tag="ACGI5H_002118"
     CDS             753..1661
                     /gene="trxB"
                     /locus_tag="ACGI5H_002118"
                     /EC_number="1.8.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430620.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0004791 - thioredoxin-disulfide reductase
                     (NADPH) activity [Evidence IEA];
                     GO_function: GO:0071949 - FAD binding [Evidence IEA];
                     GO_process: GO:0019430 - removal of superoxide radicals
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin-disulfide reductase"
                     /protein_id="HFG9697821.1"
                     /translation="MVDIIVIGAGPAGLTSAIYAMRAGLSVTVFEKNIYGGQVASTSE
                     VENYPAVQKISGVEFSNNIYNQAVAQGVDIQFDEVEEINLEGKVKVVKTSSGEHKAKA
                     VILANGVERRKLGCAGEQEFTGRGVSYCATCDGAFFKDKEVAIVGGGNTALEDALFLA
                     NNCTKVYLIHRRDSFRGEEVLEKSVKARENIEILYSHGVEKIEGEKTVSKIEVKNLKT
                     EEKRTIDVSGIFIAIGLKPNNKMFENVLDLDEGGYIISDESCITSVEGVYVAGDSRTK
                     FLRQIITAASDGAIAAVQAANYINVE"
     gene            complement(1751..3574)
                     /gene="typA"
                     /locus_tag="ACGI5H_002119"
     CDS             complement(1751..3574)
                     /gene="typA"
                     /locus_tag="ACGI5H_002119"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424463.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003924 - GTPase activity [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA];
                     GO_process: GO:0006950 - response to stress [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="translational GTPase TypA"
                     /protein_id="HFG9697822.1"
                     /translation="MSQKHKIINIAVIAHVDAGKSTLVDAFLSQSGVFRKNEVVKDCV
                     MDSNDLEKERGITIYSKNCAINYEDYKINIVDTPGHSDFSSEVERVMKTVDTVILLVD
                     ASEGPMPQTRFVLQKSLEFGLKPILFINKIDKKDQRAEEVVNEVFDLFVDLNATDEQC
                     EFPIIYGIAKQGIAKLEMDDDSEDLSPLFKTIVNHVEAYPNYDNEPLQFQISALAYDD
                     YVGRLGIGRIYKGTLKNNTQVAICREDSVVSKGKVSKLSVYEGLKQVEVDEATSGEIV
                     VIAGIPDISIGETICDLDSPLPMEMIKIEEPTLSMNFLVNDSPFVGKSGKFVTTRHLK
                     DRLEKELEVNVGLKVEPLDTTDGYKVSGRGELHLSILLENMRREGYEVGVSKPEVLMH
                     KEDGKLMEPIERVVVNCPEVYSGTIINELNMRKGMMESMSIEGDYVKIEFLAPTRGLL
                     GYRSEFINATRGEGTLVRSFEKFEEFKGEIPSRGNGVLIAQGPGVTMGYSLNALSDRA
                     VMFVDPGVEVYEGMIIGMNSRKDDMVVNPCKNKKMSNVRASGSDDAIKLSPPRIFTLE
                     EALEFIEDDELVEITPDSIRLRKRFLNEHDRLRYNKSRQGK"
     gene            3786..4028
                     /locus_tag="ACGI5H_002120"
     CDS             3786..4028
                     /locus_tag="ACGI5H_002120"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424461.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9697823.1"
                     /translation="MLEVTKIIIKYFASESDTFVKEEVCNFEELLKWSHKFIEGKKIE
                     DVLYIKSKENYKVNVIKSLEIKELEIVRKQQIPPYM"
     gene            4176..4367
                     /locus_tag="ACGI5H_002121"
     CDS             4176..4367
                     /locus_tag="ACGI5H_002121"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424459.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1450 domain-containing protein"
                     /protein_id="HFG9697824.1"
                     /translation="MIRVCPNCSNVDVNKLKTLVGEENVKTGCIGQCRAFKKEAVGII
                     DNELEIKETEAEFFEACKE"
     gene            4651..7152
                     /locus_tag="ACGI5H_002122"
     CDS             4651..7152
                     /locus_tag="ACGI5H_002122"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434034.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0042625 - ATPase-coupled ion transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0006812 - monoatomic cation transport
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="heavy metal translocating P-type ATPase"
                     /protein_id="HFG9697825.1"
                     /translation="MSSNKVVESYKITGMTCAACAKAVERVTKKMDGVYDQSVNIATE
                     KLKIEYDNSKVNFDDIKQVVEKAGYGIIKEESNKKIDMKIDGMTCAACAKAVERVVKK
                     LDGVESISVNIATDKANIDYDPSKVKLSQIKAAIEKAGYKPIEEVKNKVDVDEDKLRK
                     EREMKSLFVKFIVAIVFAVPLFYIAMGPMIIKPIGPWPLPEIINPMTNTFNYALIQLI
                     LVIPVMIAGYKFYINGFKSLFSLSPNMDSLVAIGTLAAFLYSLYTTLQIANGQIQGMH
                     HHQLYYESAGIIIALILLGKYLESKSKGKTSEAIKKLMGLQPKTAIVLVDGKEVETPI
                     EEVEIGDILLVKPGTKIPVDGVVIEGYTSVDESMLTGESIPVEKNVGSKVTGASINKN
                     GVIKFKAEKIGGDTALAQIIKLVEDAQGTKAPIAKLADTVSGYFVPIVIAIAVVASLL
                     WFLIGGKDIVFVLTIFISVLVIACPCALGLATPTAIMVGTGKGAENGILIKGGEALES
                     AHKVNTVIFDKTGTITEGKPKVTDIVLNNNVKEEYLIKIASSAEKGSEHPLGEAIVKY
                     GEEKNIKFEKVDNFKAIPGAGIQVTINDESILLGNRKLMNDNNIKLGDLEEKSNILAS
                     QGKTPMYIAVDGNLSGIIAVADVVKESSKKAIEILHDMGIKVAMVTGDNAKTANAIAN
                     QVGIDMVLAEVLPEDKSKEVEKLQNQGKFVAMVGDGINDAPALAKADIGIAIGSGTDV
                     AIESADIVLMKSDLIDVPTAIKLSHETIKNIKQNLFWAFGYNTIGIPVAAGILYVFGG
                     PLLNPMIAAAAMSLSSVSVVSNALRLKNFKAYKRD"
     gene            7312..7980
                     /locus_tag="ACGI5H_002123"
     CDS             7312..7980
                     /locus_tag="ACGI5H_002123"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424455.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000156 - phosphorelay response regulator
                     activity [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HFG9697826.1"
                     /translation="MNSSILVIEDDSNIQELISEFLSAEGYQVDTANDGLEGIQKFKQ
                     GSYDLVILDIMMPNLDGYGVCKMIRKSSSVPIIFLTALNDEGDQLKGFDLECDDYITK
                     PFSFNLLIKRVEAILRRSNKTINDKFIVFEKLKLDLNTYIAEIDGEPIELTLKEFNIL
                     KALIEKYPQVITREGLLDSIWGYDYYGDTRIVDAHIKNIRKKISLPYIKTVKGIGYTL
                     EKDI"
     gene            7964..9241
                     /locus_tag="ACGI5H_002124"
     CDS             7964..9241
                     /locus_tag="ACGI5H_002124"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424453.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing sensor histidine kinase"
                     /protein_id="HFG9697827.1"
                     /translation="MRRIFDKWEKLSIKYKLFSITTSLLIALALIIYLILYFLLPSYY
                     HEYKIESLQESLKSLVDSSIHFDTYTLEERLYYMAKDQNLAILLKDNQGKIVYGKNEV
                     VILRYSKYMINSLEDEYRTSIPIYTKDAKDGPYTLELVMPLQPIDEANEVIRKLMPYI
                     ISIAILIAIIGAYIYSIVITKPLINIIESEREQEYRRKDFVATISHELKTPITIISGQ
                     IEGMIYSVGKYKDRDTYLKKSYECTQELKDLVNEMIEVSKSEILEKDLKLVSINISEL
                     LNRLVKRQVFLIEEKHMKTILKIEENLEIKADQERITKAINNIINNAIKYSPEESELI
                     IRLYDKNKRISKKTSNQRVVLEIENTGVTIEKRYLEEIFNPFYRIEKSRSRKTGGSGL
                     GLYIVSQIFKSHGFDYSIKNKENSVVFTVEFKN"
     gene            9642..9863
                     /locus_tag="ACGI5H_002125"
     CDS             9642..9863
                     /locus_tag="ACGI5H_002125"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890241.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9697828.1"
                     /translation="MDRLKRDMKNMKEDLKEGVKKTAYVMKNTAEDLKDDAQGAMVNL
                     EMKKDEMMERYEQKKFSKELEKQMKNEMK"
     gene            complement(10152..10916)
                     /locus_tag="ACGI5H_002126"
     CDS             complement(10152..10916)
                     /locus_tag="ACGI5H_002126"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434038.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR family DNA-binding transcription
                     regulator"
                     /protein_id="HFG9697829.1"
                     /translation="MFAEERIQAILNILKKEGRVTVKELSSKFNVTEDCIRKDLKNIE
                     KISSIRRIYGGAVLARETLENQDTKDRKEINIPTKKIIAEKAFNLIEDRETIFLDIST
                     INILLAKLLAESNKKVTLVTNMLDILNVVTSKPNNLNIISTGGLLNLSLDGFVGTPTI
                     EFISKYKFDKTFMGSCGVDVFNSSLTTFEIEDGLTKKAIINSSKKVFIVMEDKKFKFD
                     GNFKFAHLEDISSIITEKTPTPDIVDILSEFNVNVL"
     gene            11190..11864
                     /gene="fsa"
                     /locus_tag="ACGI5H_002127"
     CDS             11190..11864
                     /gene="fsa"
                     /locus_tag="ACGI5H_002127"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424449.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016832 - aldehyde-lyase activity
                     [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="fructose-6-phosphate aldolase"
                     /protein_id="HFG9697830.1"
                     /translation="MQLILDTGNVEEIKELCTCLPIDGVTTNPSIVSKEKKNFKQLIN
                     EIGEIIGEDMPIHAQVLSTKYEEILEEALYISSLRKNIYVKIPVTQDGLRAIKDLHRK
                     GVKITATAIFTAHQGFLAAKAGANYIAPYVNRLDNISGDGVAMVSELIKIIDTYKMDT
                     KVLAASFKNAQQVIELMQHGVHSVTVPYDICKSMMNHPLTDWSVGKFIEDWENTFGKG
                     SKTNNI"
     gene            complement(11986..13380)
                     /locus_tag="ACGI5H_002128"
     CDS             complement(11986..13380)
                     /locus_tag="ACGI5H_002128"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905757.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="SLC13 family permease"
                     /protein_id="HFG9697831.1"
                     /translation="MGIILKPKQFYMTVIATIILYFSLNYSFNIKFSICLSFLTILIW
                     AVDSVEKTFVALFFVILAFIFNIAPIKVILQFLFTENFYIIILAYIITNAVTKTGVAK
                     IISEKLILNTVNTPKKMILLSYILGILLIFFIPQPFPRVILVSAFYKEFLKEQQITED
                     SKSILLFSIFTASTFTSMFFVNGDTLLNYVVLELGNCNINWGQWAFYMSVPTIITCFI
                     TYFLFIFVFKKELHSIKFISNENLEGNKLHFSYSNLKKEFNLLNKEQKHVFLCLGIMF
                     FMFLTQFIHNINTLIIMSICVLLLLLRKIVGFSTLKEINWKVLIFFIAAFSIGGVLKY
                     SGVVDIMGNYLIKFIPNSSEIISILFLITLTIILNICLGSAVTTSSVVIPLLGSLHIL
                     KENSVTLCLFVYIIVSIQYILPFHHATIMVGHGENLYNSKVIFKYGLTLIPLTYFIII
                     CITFPWWKFIGLEI"
     gene            complement(13458..14804)
                     /locus_tag="ACGI5H_002129"
     CDS             complement(13458..14804)
                     /locus_tag="ACGI5H_002129"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430628.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MATE family efflux transporter"
                     /protein_id="HFG9697832.1"
                     /translation="MKDLTTGHEGKSIFFFAMPMLIGSLFQQLYNTADSIIVGRFIGK
                     EAMAAVSGANPIMFLLVAALMGVSLGFSILVSQFYGSGDLKKVKATIDTTYILLFIGS
                     ILISILGIVFGGPMLKLMNTPESVFAQSKLYLTIIFSGILFSAGYNSVSAILRGLGDS
                     VTPLYFLIIATILNIVLDLTFIVVLRMGVEGVALATIMAQAVSFIISIIYLNKKHEVL
                     KFKIKGIVYDNKIFKDGLRLGLPSGVQQMLFSIGNMALQFLVNSYGTSAMAAFGAGLR
                     IENFISLPIMNLGSAVSTFVAQNIGAGENERVKKGIRESIKMTLVLAVTVIALILLFR
                     ENLIALFNTDKDVIKIGSSYLFIIGPFFLFIGTSFVLSSAMKGAGDSMFALISSIVSL
                     WLGRLPASYMLSKFFGTDGIWMGIPFGWTLGLIVTVIYYKKGHWKTKAIVNHRINE"
     regulatory      15054..15156
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00167"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="purine riboswitch; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="guanine and/or adenine"
                     /db_xref="RFAM:RF00167"
     gene            15250..16626
                     /locus_tag="ACGI5H_002130"
     CDS             15250..16626
                     /locus_tag="ACGI5H_002130"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433141.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_function: GO:0015205 - nucleobase transmembrane
                     transporter activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NCS2 family permease"
                     /protein_id="HFG9697833.1"
                     /translation="MQTTNSSTMQKLFPILTNKNVDMKKEIIAGVTTFLTMAYIIAVN
                     PNILSETGMPAGALVTGTCLAAAFGCILMGVVANLPFALASGMGLNAFFAYTVVLQMG
                     VPWEVALTAVFVEGIIFIVLSVSGVREAVVNAIPKNMKLAVTGGIGIFIALIGLVNSG
                     IVIGDQATLIKMGRFTPAVIITCVGLIIIAVLDKKRVKGSILFGIVVSSLLAWAFAFI
                     NPEYAQKLGIYLPGGLFKFESLAPIAGKIDLGYVLHPTNIGGFLVVVCTFLFVDFFDT
                     VGTLVGVCSKANMLDEKGNVPNVGRALLTDAVATTVGAGLGVSTVTTYVESSTGVIAG
                     GRTGWTAITVGILFLAAMFFSPVFIAIPSCATAPALIYVGYLMLGTVKDIEFDNITEG
                     VPAFVTIACMALTYSIGDGLTLGILTYVFVNIFYNIFGAKKAEDKKHVSVVMIVLAIL
                     FIIKLWLL"
     gene            complement(16740..17885)
                     /locus_tag="ACGI5H_002131"
     CDS             complement(16740..17885)
                     /locus_tag="ACGI5H_002131"
                     /EC_number="3.6.4.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729122.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004386 - helicase activity [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HFG9697834.1"
                     /translation="MNTFEQLKISSTLIDGLKKQDITSPTEVQSLVIGNIIQNKDLLI
                     NSQTGTGKTLAYLLPIFEKIDTSKRETQALILAPTHELVMQITNQVELLAKNAELSVT
                     SLALIGEVNIQKQIKNIKAVKPHIVIGSCGRVLDLIKQKKLKSHNIKTIILDEVDNLL
                     NGKNITCIEDIIRTTLRDRQIIGCSASLTDSTIKICDKLMKEFEIIKTKEKSQINPNI
                     NHSYLLGEIRDKFTFLRKALAATNPKKAIVFVNNEKNIEVLVSKLNYHNYKAIGIFGN
                     MEKEDRKNAINKFKLGKAKILITTDLSARGLDIVDVSHVFNLDFPKSKNEYLHRCGRT
                     ARGNRSGNTISIITKKELDIIKDLQKEFNIVITPKTLQNGELIDIIK"
     gene            18138..18845
                     /locus_tag="ACGI5H_002132"
     CDS             18138..18845
                     /locus_tag="ACGI5H_002132"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430631.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HFG9697835.1"
                     /translation="MLKVINVSKSYKNKKVVSSVSFDVNDGELFGFIGHNGAGKTTTI
                     KAIVGIHDFEEGEVLINSKSIKKQPVECKKEMAYIPDNPDLYESLTGIQYLNFIADIF
                     EVAKDKREELIKYYSNKFELNKALGDLISSYSHGMKQKLAIISALIHSPKILILDEPF
                     VGLDPKASFILKEIMREFCDKGGCIFFSTHVLEVAEKICDKIAIIKDGNIIAYGTTEE
                     VKGSNSLESIFMELIEK"
     gene            18892..20487
                     /locus_tag="ACGI5H_002133"
     CDS             18892..20487
                     /locus_tag="ACGI5H_002133"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434052.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HFG9697836.1"
                     /translation="MSNLSILIKTNIINEFKLNALKKADGREKQKIMGMMLSVVIIAG
                     LLIFYVTSLSLSLVDILKQINQLEMLLIFGFGLSTLTTIVTSLYKTSSYLFQAKDLDL
                     LTSLPIKESTVLASKILMLVGANYLFSSICMIIPAVVYFLNSDVSITYFPYLILLFLA
                     LPLLPIVASSIIFLFIGQISSRIKYKNLVLIIGSIILMLLYTLLMSRLNSMSVEMLKN
                     SVSISETIRKVYPPIYYFVDALKTGSIVSFLAFIAISIIPFFMFVTLFAKKFKDINAK
                     MSEGYKSKNYEFKGQKTSRPSKALLKKEFKRYTSSFIYFLNSSAGLLFLMVGTILILL
                     FGADKVGELLKLNIDFNLIKIQLLGVFFFIIVMNCTTYCSISLEGKNLWILKSSPIDE
                     REIFWSKILMNFLLNAPLSILCLILVSIRLDFEIQFIIVSICLIVSFSMFVALMGLLS
                     NLLYPNLDWKNEVAVVKRSASMIVTMLVSLAYVIILGGIYVLLGISFLNIYIILASIL
                     TLILDFMIWRIISTKGVRIFKNL"
     gene            20590..21672
                     /locus_tag="ACGI5H_002134"
     CDS             20590..21672
                     /locus_tag="ACGI5H_002134"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424437.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="lysylphosphatidylglycerol synthase transmembrane
                     domain-containing protein"
                     /protein_id="HFG9697837.1"
                     /translation="MRKLSKREKDFIQYGFLLFLICITTYLVLTTLDIKLIPKIIRLV
                     NKTYIFLGILTIIVYMIIESIVTHLIINAVQKTKVKFIGIKMATMGFYYNLVTPFASG
                     SQPMQIYALTKYDVSLSKSVAIVTNKTVVFQSTVTVFCGILILLNKSLLMEQVHSVKV
                     LITFGMIMNVSMLLGGLLIVFSPKQVKMIAEVLINFLSKFKTFKFLDSKRDRINHYID
                     DYNYSIKIFIKNVRILVLSILLTVLQLIAYFSIVYCVYKASNLRGVSYVHIMTLQVFL
                     YMAISPIPTPGNVGANEVTFFTMFSNIIPKELLGYSVLLYSGFVYYFILIVSGLFTFG
                     THYTLNSWKKENKVNSNLDKVIEKLN"
     gene            21821..21982
                     /locus_tag="ACGI5H_002135"
     CDS             21821..21982
                     /locus_tag="ACGI5H_002135"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905751.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III"
                     /protein_id="HFG9697838.1"
                     /translation="MKQDKQNEKQSEISKIKQSNDNKLEIAQELHVSKNIGNMLGYRI
                     DKKKMNRPS"
     gene            22323..23591
                     /locus_tag="ACGI5H_002136"
     CDS             22323..23591
                     /locus_tag="ACGI5H_002136"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433135.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0015297 - antiporter activity [Evidence
                     IEA];
                     GO_process: GO:0006812 - monoatomic cation transport
                     [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA];
                     GO_process: GO:1902600 - proton transmembrane transport
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cation:proton antiporter"
                     /protein_id="HFG9697839.1"
                     /translation="MEASIHTIASNNLLIIFAIVSITGIICSKLSEIIKVPDVVLYLL
                     VGILIGPSFLKFIDIRGFQIENQLILTFGSAFILYLGGKEISLKVLRNVKISVFLLAT
                     LGVVISAFIMQQVIGFTFGISAMTALLAGTIIASTDPATLVPIFNQVKIKDRVKQTVI
                     SESAFNDATGAILTSAVLAVILSNKFSLGENIYELGTMVIVGVLVGLITGILLLKLVN
                     DKPYGIFKDFAPIISVISVVVAYELSTKLGGSGYMSCFIVGIITGNKKNFKIWLSQKS
                     YDADFYVAETLGTICRMAIFIILGSQVNLAQLSKYFMPSVITVLVLMFIARPLCVLVC
                     TLVDREAKWSKSEILFMMWVRETGVIPAALCGIISAMKVPGYEVISSVVFMTILITLV
                     IQGSTTKLVAKKLGLLEEEVINISEKVSTF"
     gene            23786..24574
                     /locus_tag="ACGI5H_002137"
     CDS             23786..24574
                     /locus_tag="ACGI5H_002137"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424428.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="FAD binding domain-containing protein"
                     /protein_id="HFG9697840.1"
                     /translation="MFTVMDIVQPDTVEEAYSILNKRKTNQVIGGSAFLRMGKKRIGT
                     GIELSKLNLDYIKEYEDYVEIGSMTTFRTLETSSIIKNNFGRIIEDSVKNIIGVQFRN
                     VVTVGATVFSKYGFSDLIVALLSLDTEVELYNIGRISLEEFLNRDYEKDLLIKIYIKK
                     TNKNASYKSIRNAKSDYPILNVSVSKHMEQFKLCVGARPQKATIAKQASEFLSNNEIN
                     EINIDKAVEIASEELTFGSNMRASREYRKAMSKVLLKRAIMEVI"
     gene            24574..25023
                     /locus_tag="ACGI5H_002138"
     CDS             24574..25023
                     /locus_tag="ACGI5H_002138"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="2Fe-2S iron-sulfur cluster-binding protein"
                     /protein_id="HFG9697841.1"
                     /translation="MLVKININGKKKSVDIEPEEYLVDTLRKVGNLSVKRGCDTGCCG
                     LCTVLIDKKPTLSCATLTLRALDKEITTIEGLENEVKEFSEVLVKEGAEQCGFCSPGF
                     ILTVLAMKDELENPTDDEIKHYLTGNLCRCTGYMGQLRAIKTYLEVK"
     gene            25027..27291
                     /locus_tag="ACGI5H_002139"
     CDS             25027..27291
                     /locus_tag="ACGI5H_002139"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430642.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="molybdopterin cofactor-binding domain-containing
                     protein"
                     /protein_id="HFG9697842.1"
                     /translation="MNIVGKGIKKIDGMSITTGKPVYTDDLSAKDALVVKILRSPHAY
                     AKIKDIDTSKAEMVDGVECVLTYKDVPKSRFTLAGQTYPEPSPYDRLILEDVVRYVGD
                     EVAIVAAIDEKTAIKAMNLIKVKYEVLTPVLDFEEAIGNKTMVHDEDRHCNFDIGMQR
                     EKNIVSHHDYTKGDVEKVLSNCDVVIEETYYTQAQAHAMMETYRAYNYLDHMGRLVVV
                     SSTQIPFHVKRHLSRALEIPASKIRVIKPRIGGGFGGKQTACVEIFSAIVTLKTGKPA
                     KIIYDRKETFNCSTSRHAMRLKVRLGATNDGIIKAIDIKALSDTGAYGEHASTTIGLV
                     GEKTLPMYNKVEATRFIADVVYTNKMPAGALRGYGASQGCFAVESTINMLANKLKMDP
                     TDLRLKNVVTEGETTFAYGKTLNSVDLIKCINKGKELIGWNEKYPCKHLDNGKIRSVG
                     MAITMQGSGIQGLDKSSAEIKLNDCGDYTLMIGSTDMGTGSDTILAQMAAEVLDTSIE
                     NITVISADTDLVPYDPGSYASSTTYVTGMAVVKAAQDLREKIISAGATKLGVEKDEVE
                     FDGIKLTSKKGSTLLFDIAVDSTIGPDTNQLIGLASHGSPVSPPPFIAGFAETEIDTE
                     TGKVDLVNYVAVVDCGTVINKNLAKIQVEGGIVQGIGMALFEEVRYTEKGSMDTNTFM
                     QYKIPARCDIGNVKVDFVETYEPTGPFGAKSVGEVVINTPLPAIQEAVFNGIGVRINT
                     LPITPEKVFMEMNK"
     gene            27431..27742
                     /locus_tag="ACGI5H_002140"
     CDS             27431..27742
                     /locus_tag="ACGI5H_002140"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433131.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9697843.1"
                     /translation="MAGNLNNMRAVNNFRGDKNILECLVSFEGRSISQRKVRVFFKEK
                     QNQIEIDFAEEEISKLVENVVLNTSYQEMLYDEIEKQLEIDCIGTWMILSKLKDGSRV
                     H"
     gene            28028..28528
                     /locus_tag="ACGI5H_002141"
     CDS             28028..28528
                     /locus_tag="ACGI5H_002141"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424418.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="QueT transporter family protein"
                     /protein_id="HFG9697844.1"
                     /translation="MRKNSINIALTAAITAIYAVLTLSLGFISYGPIQFRVAEIMMLL
                     AFLDKGYIVGLTLGCFLANVIGPYGVPDIIFGTLATFISASMIYITRKLGKQNKSTLV
                     IASLWPTVINSIVVGLMLNVFFGLPLILSMIQVGFGEFVVVTIVGVPFFCFLMKKYKN
                     VINIKF"
     gene            28585..29571
                     /locus_tag="ACGI5H_002142"
     CDS             28585..29571
                     /locus_tag="ACGI5H_002142"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893441.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HFG9697845.1"
                     /translation="MSKVKRLTDVWIYINDKQKFTIKELSEEFNLSAKTIQRYLKELN
                     KMGLPIQAEQGRNGGYRVLNNSYIPPVIFTEKEVMIILFALKSLQIYNYKLMEIEINS
                     IMRKVSYERKSSIKVGIENIKRYIGFVANDTNDGDFKSSNVTEFFRASSESLILNIKY
                     KCGNQILEKNVCPIGIYLNKGAWFSPAYDCKSDKIILVHIDNIIDIKRTGESKKIHIN
                     LEEWLHEVYNNLYGNSSTTKKFGEIIYLNVLLTKEGVSKIKDSSWNLDMELNEDGSGI
                     ISTFIKVEDIDCYASILFFIGNNAKVIEPKFLNKLLYDKANELRYFYEENMV"
     gene            29621..30343
                     /locus_tag="ACGI5H_002143"
     CDS             29621..30343
                     /locus_tag="ACGI5H_002143"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424413.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein"
                     /protein_id="HFG9697846.1"
                     /translation="MENFNKNAKIIGIGAEGINIINEVEEKIKANMDIEKININQEIE
                     KEYVRSLLDGVDILFLIYSSEDKHIRDIIKAVSYMSNERRVLSIGMDCSEKENKEDLE
                     LGREFKINNDSIFKFVDLMNIMVESISDSCMINIDITDLKEAIVGDKGIKYSFEEFED
                     TKSYSEIADILFDRMEYIGEEFISKKGIVFVEGSPEFSIMELNDLISNIQSKVEESYE
                     VIFSLYIKENLNGNIRVGLLYN"
     gene            30372..32306
                     /locus_tag="ACGI5H_002144"
     CDS             30372..32306
                     /locus_tag="ACGI5H_002144"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893437.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HFG9697847.1"
                     /translation="MSENIRGTEYWLMEEFFYQETDTPQIFREESIIALGFDIKINLK
                     KVFSMGKKSEKYINENCNDKDFIKKFMSIKKGDYFLYKAYQNIEEKVKCNVSIGIVEE
                     DFENGYELSHILGHTLPVKWMHNFDTVSNCKVYTSEFYKLNNNDISSYLEIIKSQDKK
                     LLRKRIEESENNKWYLKNYYYKNVDKCVDDEELFIQPINLEQLESLKNIKTDDYILLY
                     NSEKVICENDHTMKSLFGVCQVMEGFDKEKVSALEGGYFFPVRWIEYEKENIDGNAWV
                     IFENNSIVEKYVKRFTNKMPLNTILYGPPGTGKTYNTKQMVYNLVSETSLRNRYYTGY
                     LDYKNNVEFCTFHQSYGYEEFIEGLKSDGEGNFKPEDGILKDISIEACYNALKFEKKM
                     SFELEKDSLTLETIKDRKKKLVLENIEYSESFNFEESENYVLIIDEINRGNVSKIFGE
                     LITLLEDDKRLTKSNQTIVKLPYSKEKFSLPPNLYIVGTMNTSDKSIALLDIALRRRF
                     NFEEIMPDYDLLSIVDGIDIRKMLYTINKRIEFLYDRDHVIGQAYLLAVENINDIVVV
                     FRSKIIPLLQEYFYYDSEKVGLILGGIGRNEKDKYIVYKEKLIASELFKNNNASIMES
                     KVNYCIKQNISSEELKNIYE"
     gene            32299..>33486
                     /locus_tag="ACGI5H_002145"
     CDS             32299..>33486
                     /locus_tag="ACGI5H_002145"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018112798.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="McrC family protein"
                     /protein_id="HFG9697848.1"
                     /translation="MSKNIYVKETYEWIRIGNGENELTEIEYEKLLKYLENNNDVLKS
                     NIIDIKYKKLRFINYVGIICFENVILEILPKLSLSDNLVKDREILLQMLSICNKIPIT
                     MNEKIRLSLKNYNLLNFFVMYFIESMQTQMKKGIYFEYINKIENLNVMRGKILLSTYA
                     KEKGISPMKIRCEYDEYSENNFLNQVLKKACISILCRINDNSIQGKIKKILSYFQNVD
                     LIYIDRKKLLDYKFYKNNDRFKDCYLLARLLLLNLSMDNSQNNQEAFSILFEINTLYE
                     EYIGILIKSIWDNSFRETYIQDKSKFLLKNEQTGKKNFNLRPDIVLYDLKNEYEIIID
                     TKWKAIEVDSNVFYRSSDIYQMYAYITAYENAKRCILLYPCIQKDKNYSSWKLSESFK
                     GKFI"
BASE COUNT        13014 a         3628 c         5467 g        11377 t
ORIGIN      
        1 agtattaata taaaaatttg gaaaaaatat tttttaaatt gtaaaaaaat tgtaatcaaa
       61 ttgagtatta gaaaaatatt tttttaactt ttttaaaagt ttaaaaacct agattttcat
      121 agtgatgaag ctgtttttaa tgaaagtaat taaaagataa ctattaaata tctgtaatat
      181 tacaatttta tactacacta tattacaaaa aaagtttaca aaactttaat ttgaaaaatg
      241 taattatatg gtatatcata taaatataag taaatagtgc taatatttaa actattaatc
      301 ataattggtt caacaaaagt atatagttaa taatgtttaa tttgaagaaa ttgttagtgt
      361 gaaattacat atatattcaa attaaattca taaatatttc acataataat agtatactgt
      421 aaacaaaagg aggtattaaa tatgggaata gtacttataa cagcagcatt agttttggtt
      481 atgtatggac tttcaattct atcatatata tcagaaagca atatattaga agacactgta
      541 aatgataacc aataaggttt tgaattatat aaataagtga gaactgtaaa taaaagttaa
      601 tttttatttg cagttttttt atatatatgt aaaataaagt taattaataa aaaataatgt
      661 tttgtttata gtatatatgg ataataatag taaagtataa gaatgatgag aataatatat
      721 aagaaataat aatataaaga gaggtaaacg ttatggtaga tatcattgta attggtgctg
      781 gaccagcagg tttaacttca gcaatttatg ctatgagagc agggttaagc gttacagtat
      841 ttgaaaaaaa tatttatgga ggtcaagttg caagtacctc tgaggtagaa aattatccag
      901 cagttcaaaa gatttctggg gtagaatttt ctaataatat atacaatcaa gcagttgctc
      961 aaggtgttga tattcagttt gatgaggttg aagagataaa tttagaggga aaagtaaagg
     1021 ttgtaaaaac ttcttcaggt gaacataaag caaaggctgt tattcttgca aatggagttg
     1081 aaagacgtaa attaggttgt gcaggggaac aagaatttac aggtagagga gtatcttact
     1141 gtgcaacatg tgatggagcc ttttttaaag ataaagaagt tgctatagta ggtggaggaa
     1201 atactgcact agaagatgct ttatttttag ctaataattg tacaaaagtg tatttaattc
     1261 acagaagaga tagttttaga ggtgaagaag tgttggagaa atctgtgaaa gcaagagaga
     1321 atattgagat actttacagt catggtgtag aaaaaataga aggagaaaag actgtatcga
     1381 aaatagaagt aaaaaactta aagactgaag aaaaaagaac tatagatgtt agtggtattt
     1441 ttattgctat aggtcttaaa cctaataata aaatgtttga aaatgttctt gatttggatg
     1501 aaggtggata tataatttca gatgagtctt gtataacatc agtagaaggt gtatatgtag
     1561 caggagatag tagaactaag tttttacgtc aaataataac agcagcatca gatggagcta
     1621 ttgcagccgt tcaagcagct aattatataa atgttgaata atataaattt caaataaaaa
     1681 tagccatata aactgaaata atttttcagt actatatggc tattttgtta attagaggta
     1741 aatgtacgtt ttatttacct tgtctagatt tgttatatct taatctatca tgttcattta
     1801 agaatctttt tctaagtctt atagaatcag gtgtaatttc aactaattca tcatcttcta
     1861 taaactctag tgcttcttca agagtaaata ttctaggagg agataatttt atagcatcat
     1921 ctgaaccaga agcacgtacg ttactcattt tcttgttttt acaagggttg actaccatat
     1981 catcttttct ggaattcata ccaattatca taccttcgta aacttctaca ccagggtcta
     2041 caaacattac agctctatca cttaaggcat taagagaata ccccatagta acaccaggtc
     2101 cttgtgctat taaaacacca tttcctcttg aaggtatttc tcctttaaat tcttcaaatt
     2161 tttcaaatga acgaactaaa gtaccttctc cacgagtagc gtttataaat tcacttcgat
     2221 atcctaaaag accacgagta ggtgctaaga actctatttt tacatagtct ccttctattg
     2281 acatagactc catcatacct tttctcatgt ttaattcatt tataatagta ccagagtaaa
     2341 cttcaggaca gtttacaaca actctttcta ttggttccat taattttcca tcttctttat
     2401 gcattaaaac ttcaggttta gaaacaccaa cttcataacc ttcacgtctc atattttcaa
     2461 gtagtataga taagtgaagc tctccacgtc cagaaacttt gtatccatca gtagtatcaa
     2521 gaggttcaac tttaagacca acatttactt caagttcctt ttcaagtcta tctttcaaat
     2581 gtctagttgt aacgaatttt ccactttttc caacgaatgg agagtcgttt actaagaagt
     2641 tcatagaaag agtaggctct tctattttta tcatttccat aggtagtgga ctatctaaat
     2701 cgcatatagt ttcacctata gatatatcag gaataccagc tataacaact atttctccac
     2761 tagtagcttc atcaacttca acttgtttta aaccttcata cacagaaagt tttgatactt
     2821 ttcctttaga tacaacagaa tcttctctac atatagcaac ttgtgtattg tttttaagag
     2881 tacctttgta aattctacct ataccaagtc tacctacata atcatcatat gcaagagctg
     2941 atatttggaa ctgtagaggt tcattatcgt aattaggata agcttcaacg tgatttacaa
     3001 tagttttaaa tagaggagaa aggtcttcac tatcatcatc catttcaagt ttagcaatac
     3061 cttgtttagc aataccatat attataggaa attcgcattg ctcatctgtt gcatttaagt
     3121 ctacaaataa atcgaaaact tcattaacta cttcttccgc tctctggtct tttttatcaa
     3181 tcttgtttat aaataatatt ggttttaaac cgaactctaa agatttttgt aaaacgaatc
     3241 tagtttgagg cattgggcct tcactagcat caactaatag aataactgtg tcaacagttt
     3301 tcataacacg ttcaacttca gaagaaaagt cactgtgtcc tggagtatca actatgttta
     3361 ttttgtaatc ttcatagttt attgcacagt tttttgaata tatagttatg cctctttctt
     3421 tttcaaggtc gttactgtcc ataacgcagt ctttaactac ttcgttcttt ctaaaaacac
     3481 cgctttgaga aaggaaagca tcaaccaatg ttgattttcc agcgtcaacg tgggctataa
     3541 ctgcgatatt tataatttta tgtttttgtg acatttttgt tgctcccttc gattaaaata
     3601 acttattaat tatagcacaa tatattatta ggtacaagga ggaatatatt aaattgtatt
     3661 aatatagttt aaattgaata aaactgttag ttttgcatct gaaaattatt ttgtttaaaa
     3721 aaatttttta gacaaataat aaccttaata gataaaaaga ttaataaaag agtaaaggat
     3781 gatatatgtt ggaagtaacc aaaataataa ttaaatattt tgcaagtgaa agtgatactt
     3841 ttgtaaaaga agaagtttgt aattttgaag aacttcttaa gtggtctcat aaatttattg
     3901 aaggtaaaaa gatagaagat gttttgtata taaagtctaa agaaaactat aaagtaaatg
     3961 tgattaagtc tttagaaatt aaggaattgg aaatagtgag aaaacaacag ataccaccgt
     4021 acatgtagta ttaataatat ataaaattaa tatgtaatac tcgcaatagg atataaatgg
     4081 tatatatggt aataatttat attaaaaaaa cttttataaa gtttatattt gggtataaaa
     4141 gtattaatta gacattaatt aggaggaact taaatatgat aagagtatgt ccaaactgtt
     4201 caaatgtgga tgtaaataag ctaaaaactt tggttggaga agaaaatgta aagactggtt
     4261 gtataggtca gtgtagagca tttaaaaaag aagctgttgg aataatagac aatgagcttg
     4321 aaataaagga aacagaagca gagttttttg aagcatgtaa agaataaatt ttaaataaaa
     4381 tataataaat agagcatcta aattgtataa gcattaaaca atttagatgc tctattttta
     4441 tatatacatt taattatgag tatacttttc tattaaatac aaataaatat aactaataca
     4501 tttatttatt aaaaaaatat tgatttaata tacctatagg gggtataata aaaatataga
     4561 tttctaaata agtaatttat caatattaca tatcaaaata aaacgttaca aattagctga
     4621 aaatatattg aaagaaagga agattttatt atgagttcaa ataaagtggt agaaagttat
     4681 aaaattacag gtatgacatg tgcagcttgt gcaaaggcag tagagagagt aactaagaag
     4741 atggatggag tatatgacca aagtgtaaat atagctactg aaaaacttaa aatagaatat
     4801 gataattcta aggttaattt tgatgatata aagcaggttg tagaaaaagc aggatatgga
     4861 attataaagg aagaaagtaa taaaaaaatt gatatgaaaa ttgatggaat gacatgtgca
     4921 gcttgtgcaa aagctgtaga gagagtggta aaaaaattgg atggagtaga aagtattagt
     4981 gtgaatattg caacagataa agctaatata gactatgacc catcaaaagt aaaattatct
     5041 caaataaaag cagctattga aaaagctgga tataaaccaa tagaagaggt aaaaaataag
     5101 gttgatgtgg atgaagataa attgagaaaa gaaagagaaa tgaagtcttt atttgttaaa
     5161 tttatagttg caatagtatt tgcagtacct ctgttttata tagcaatggg acctatgata
     5221 ataaagccta tagggccatg gcctttgcca gaaattataa atcctatgac aaatactttt
     5281 aattatgcat taattcagtt aattttagta ataccagtaa tgatagctgg ttataaattt
     5341 tatataaatg ggtttaaatc acttttttct ttaagcccta atatggattc tttagttgca
     5401 ataggaacat tagccgcatt tttatatagt ctatatacga cactacaaat agccaatgga
     5461 caaattcaag gtatgcacca tcatcagttg tattatgaaa gtgcaggaat aataatagca
     5521 cttatcttac ttggtaaata tttagaatca aaatcaaaag gaaaaacatc agaagcaatt
     5581 aaaaagctta tggggctaca acctaaaact gcaatagtgt tagttgatgg taaagaagtt
     5641 gaaactccta tagaagaagt agagatagga gatatactat tagtaaaacc aggaactaaa
     5701 atacctgtgg atggagttgt aatagaagga tatacatcag ttgatgaatc aatgcttaca
     5761 ggtgaaagta taccagtaga aaagaatgtt ggaagtaagg tgacaggagc tagtattaat
     5821 aaaaatggtg ttattaagtt taaggctgaa aaaattggtg gagatactgc tcttgcccaa
     5881 ataataaagt tagttgaaga tgcacaaggt acaaaagcac ctattgctaa acttgccgat
     5941 actgtatctg gatattttgt accaatagta attgcaatag ctgtagttgc atcattattg
     6001 tggtttttaa taggaggaaa agatatagta tttgtactta ctatatttat atcagtactt
     6061 gtaattgctt gtccttgtgc attaggatta gcaacaccaa ctgctataat ggttgggact
     6121 ggaaagggcg cagaaaatgg aatcttgata aaaggtggag aggcattaga atctgcacat
     6181 aaagtaaata cagtgatatt tgataaaaca ggtactataa cagaaggaaa gccaaaagta
     6241 acagatatag tattaaataa taatgtaaaa gaagaatatc ttatcaagat tgcttcaagt
     6301 gcagaaaaag gttcagaaca tcctcttgga gaagcaatag ttaagtatgg agaagagaag
     6361 aatataaaat ttgaaaaagt tgataatttt aaagccatac caggtgctgg tatacaagtt
     6421 actattaatg atgaaagtat attacttgga aatagaaagc ttatgaatga caataatata
     6481 aagcttgggg atttagaaga aaaatcaaat atattggcaa gccaaggtaa aacacctatg
     6541 tatatagctg tagatggaaa tttatcaggt ataatagcag ttgcagatgt agtcaaagaa
     6601 agtagtaaaa aagcaataga aatacttcat gatatgggaa taaaagttgc aatggtaact
     6661 ggagataatg cgaaaactgc aaatgctata gcaaatcaag tcggtataga tatggttttg
     6721 gcagaggttt taccagaaga taagtcaaaa gaagttgaaa aactacaaaa tcaaggaaag
     6781 tttgttgcaa tggtagggga tggaataaat gatgccccag ctcttgcaaa agcagatata
     6841 gggatagcaa taggaagtgg aacggatgta gccattgaat ctgcggatat agtacttatg
     6901 aagagtgatt taattgatgt tccaacagca attaaactta gtcatgaaac tataaaaaat
     6961 ataaaacaaa acctattttg ggcatttgga tataatacaa ttggtatacc tgtagcagca
     7021 ggaatattat atgtatttgg aggaccttta ttaaacccaa tgattgcagc agcagcaatg
     7081 agcttaagtt cagtttcagt cgtatcaaat gcacttagac ttaaaaactt caaggcatat
     7141 aagagagatt agattaataa attaaataaa atgtatccaa aagagctatc tttaaattaa
     7201 aaggattaat ttacaaatta agatagctct tttttcatgt aaaattcaca acaataagat
     7261 aaaatataag taatatacga aattttaaat aaaatagaaa ggattgatag aatgaattcg
     7321 tcaatacttg taattgaaga tgattcaaat atacaagagt taatatcaga atttttaagt
     7381 gcagaaggtt atcaagttga tacagcaaat gatgggttgg aaggtataca aaagtttaag
     7441 caaggaagtt atgatttagt aatattagat ataatgatgc caaacttaga tggttatgga
     7501 gtttgtaaaa tgataagaaa gtcatcaagc gttccaatta tatttttaac tgctttaaat
     7561 gatgaaggag accaacttaa agggtttgac ttagaatgtg atgattatat aacaaaacca
     7621 ttttcattta atcttcttat aaaaagagta gaagcaattt taaggcgaag taacaagact
     7681 ataaatgaca aatttatagt ttttgaaaaa ttaaaattag atttaaacac atatattgca
     7741 gagatagatg gagaacctat agaacttaca ctaaaagagt ttaatatatt aaaagctttg
     7801 atagaaaagt atccacaagt tataactagg gaaggtcttt tggatagtat atggggttat
     7861 gactattatg gagatactag gattgttgat gcacatataa aaaatataag aaaaaaaata
     7921 tcattaccat atattaaaac tgtaaaagga ataggatata cacttgagaa ggatatttga
     7981 taagtgggaa aagttaagta taaagtataa gttattttca ataacgacat cattattaat
     8041 agcattagct ttaataatat atctaatttt atatttttta ttgccatcat attatcatga
     8101 gtataaaatt gagtctcttc aagaaagttt gaaatcttta gtagatagtt caattcattt
     8161 cgatacatat actttagaag aaagacttta ttatatggct aaagaccaaa atttggctat
     8221 tttattaaaa gataaccaag gtaaaattgt atatggtaag aatgaagtag ttattttaag
     8281 atatagtaag tacatgatta atagtcttga ggatgagtat agaacttcta tacctatata
     8341 tactaaagat gcaaaagatg gtccatatac tttagaactc gttatgccat tacaaccaat
     8401 tgacgaagca aacgaagtta taagaaaact aatgccatac atcatatcaa tagcaatatt
     8461 gatagcgatt attggagcat atatatattc aattgtaata acaaagcctc ttataaacat
     8521 aatagagagt gagagagaac aggaatatag aaggaaggat tttgttgcta caatatcaca
     8581 tgaactaaaa actccaataa ccataataag tggtcaaatt gaaggtatga tttatagtgt
     8641 aggtaagtat aaggataggg atacttatct gaaaaaatcg tatgagtgta cacaagaatt
     8701 aaaagattta gtaaatgaaa tgatagaggt ttcaaaatca gaaatacttg aaaaagattt
     8761 gaaattggta tcaataaata taagtgaatt attaaataga cttgtaaaga gacaagtatt
     8821 tttaatagaa gaaaaacata tgaaaactat tttaaaaata gaagaaaatt tggaaattaa
     8881 agcagaccaa gagagaataa ctaaggcaat caataatata ataaataatg ccataaaata
     8941 ttctcctgaa gaatcagagc ttataattag actctatgat aaaaataaac gaataagtaa
     9001 aaagacttct aatcaaagag tggttttaga aattgaaaat actggtgtaa ctatcgagaa
     9061 acgttattta gaagaaatat ttaatccatt ttatagaata gaaaaatctc gttcgagaaa
     9121 aactggagga agtggacttg gactttatat agtcagccaa atttttaaaa gtcatgggtt
     9181 tgattatagc ataaaaaaca aagaaaactc tgtagtattc acagtagaat ttaaaaatta
     9241 attacttatt ataaagaata tataactttc aataatagtt cattttaaaa tcacaaaaaa
     9301 ttcataatga aactgtatta tataaatata aataagctta aaaccataaa atacaccaac
     9361 tataatgatg agatttcctt acatcctcca tataagtcat cattatagta acccaacaat
     9421 taagttacta tgaatttaaa aaataacacc gagcatataa tctatgctta gtgttatttt
     9481 tattttgaaa taaaaaatat ttaatttatt gaaatgtata gatttagata gtttaaacta
     9541 tatttaagac ttaaaaatta taattgatat tacaaataaa tatatgtact ttgggaaaaa
     9601 taaatatagg aagtattata tttacagagg aggtagtttt gatggataga ttaaaaagag
     9661 atatgaaaaa tatgaaagaa gatttaaaag aaggtgttaa aaagacagct tatgttatga
     9721 aaaatacagc tgaagatttg aaagatgatg cacaaggtgc tatggtaaac ttagaaatga
     9781 aaaaagatga gatgatggaa agatatgaac aaaagaaatt ttctaaagaa ttagagaagc
     9841 aaatgaagaa tgaaatgaaa taagctttta tttatgaata acaaattatt gtattcatat
     9901 aaaaagtagc cagtaatatt aaatagttta tttaaggaaa tagactttct aaaaataact
     9961 gtattagatt tagaaagtct atttcaaatt agttttataa atagacataa ggataaagta
    10021 gatgttatag aactagattt taaaaaatag atactaagga taaaataaat attatagaaa
    10081 tatgttttta agaatattta tcaaataaaa atttatattt ataagaaatc ctataaaaca
    10141 tataattaaa cttataaaac atttacatta aattctgata aaatatctac tatatcagga
    10201 gtaggcgttt tttctgtaat tatagaacta atatcttcta aatgagcaaa cttgaaattt
    10261 ccatcaaatt taaacttttt atcttccata actataaata cttttttact tgaatttatt
    10321 atagccttct tcgtaagacc atcttcaatt tcaaaagttg taagtgaaga gttgaataca
    10381 tctactccac aacttcccat aaaagtctta tcaaacttat atttcgatat aaactctata
    10441 gttggagtac cgacaaaacc gtctaaactg agatttaata aacctccagt ggaaattata
    10501 tttaaattat ttggttttga agtaactaca tttagtatat ccagcatatt tgtaacaagt
    10561 gttacttttt tattactttc agctaacaac ttcgcaagca agatgttaat tgtagagata
    10621 tctaaaaata tagtttctct atcttcaatt aaattaaatg ctttttctgc tattattttc
    10681 tttgttggaa tattaatttc ttttctgtct tttgtatcct gattctctag tgtttctcta
    10741 gctagtacag ctcctccata aattcttctt attgaagaaa tcttttctat attttttaaa
    10801 tcttttctta tacaatcttc tgtaacatta aatttagaac tgagctcttt gacagtaact
    10861 ctaccttctt tttttaggat atttaatata gcttggattc tttcttctgc aaacattttc
    10921 tacctctttt cgcaatatag tattatagta aatattataa gataaaatac aatatatcaa
    10981 ctattttaac atgaaataca aaattaattt aatataaaaa gtatgttttt tctaactata
    11041 tatttagaat ttagtaaata aaaaaattat aaaactaaga aggaaaagta aaacaataat
    11101 aaaaaataaa aaacaataag caaaatgttg aaaataatac caaatcaata tataataaga
    11161 ataaagaaag attaaagggg gatattttaa tgcaactaat cttagataca ggtaatgtgg
    11221 aggagattaa ggagttatgt acttgtttac caatagatgg tgtaactaca aatccaagta
    11281 ttgtttcaaa agaaaaaaag aattttaagc aacttataaa tgaaattggt gagattatag
    11341 gtgaggatat gcctatacat gctcaagtgt taagtacaaa gtatgaagaa atattagaag
    11401 aagcattata tataagtagt ttgagaaaaa atatatatgt aaaaatacct gtaacacaag
    11461 atggtttaag agctataaaa gaccttcaca gaaaaggtgt aaaaataact gctactgcaa
    11521 tattcactgc tcatcaaggt tttttagctg caaaggctgg agcaaattat attgcacctt
    11581 atgtaaatag gcttgataat atatctggtg atggagtagc tatggtttca gaacttataa
    11641 aaataataga tacttataaa atggatacaa aagtacttgc agccagtttt aaaaatgcac
    11701 aacaagttat agaattaatg caacatgggg tgcatagtgt tacagtacca tatgatattt
    11761 gtaaatctat gatgaatcat ccattaactg attggagtgt aggtaagttt atagaggatt
    11821 gggagaatac ttttggaaaa ggaagtaaaa caaataatat ttagtattat ggtaaaagag
    11881 tagttttgtc caatttcaca agaacttata taaaaagatg aaaatatgaa ttttcttttt
    11941 aataatttcg ttattatctt aagttaattc atattttcat cttttttaga tttctagtcc
    12001 tataaatttc caccaaggga atgttataca tattattata aagtaggtta aaggaatcaa
    12061 agttaaaccg tatttgaaaa taaccttgct attatacaga ttttcaccat gaccaaccat
    12121 tattgtagca tgatgaaatg gtaatatgta ctgtatgctt actataatgt agacaaatag
    12181 acataaagta acactatttt cctttagtat atgtaaactt ccaagtaacg gtattactac
    12241 agatgatgta gtgacagcac ttccaagaca tatattcaag attattgtga gagttatcaa
    12301 aaacaatatt gaaataattt ctgaagagtt tggtataaac tttatcaaat aatttcccat
    12361 tatatctaca actccagagt actttaacac tcctccaatt gaaaatgctg ctataaaaaa
    12421 aataaggacc ttccaattta tttcttttaa agtactaaat ccaactattt ttcttagtaa
    12481 taaaagaagt acacaaattg acattataat taatgtgttt atgttatgta tgaactgagt
    12541 taaaaacata aaaaacatta ttcctaggca taaaaatacg tgtttttgct ctttgtttag
    12601 caaattaaat tcttttttta aattagaata tgaaaaatga agtttattac cctcaagatt
    12661 ttcattagaa ataaatttta ttgaatgcaa ttctttttta aagacaaaga taaataaaaa
    12721 ataagttata aaacaagtaa ttatagttgg aacagacata taaaaagccc attgacccca
    12781 atttatatta caatttccaa gttctagtac aacataattt agaagggtgt ctccatttac
    12841 aaaaaacatt gatgtaaagg tagatgctgt aaatatacta aataaaagta tagattttga
    12901 atcttcagtt atctgttgtt cttttaaaaa ctccttgtaa aaagcagata caagaataac
    12961 ccttggaaat ggttgtggga taaaaaatat taaaagtata cctaaaatat acgataaaag
    13021 aatcattttt ttaggggtat ttacagtatt taaaattaac ttctcagaaa taatttttgc
    13081 gacacctgtt tttgtaactg cattagtaat tatgtatgca agaattatta tgtaaaaatt
    13141 ttctgtaaat aaaaactgta aaataacctt tattggtgca atgttaaata taaacgctag
    13201 aattacaaaa aacaatgcaa caaaagtttt ttcaactgag tctacagccc atatcaagat
    13261 agttaaaaaa gataagcata tagaaaattt tatgttgaaa ctgtaattaa gagagaagta
    13321 gagaattatg gtagctataa cagtcatata aaattgtttt ggcttaagaa taatacccat
    13381 ttttatattc acctccataa tttattatat cataatggag gtgaatacaa tgaatgtgaa
    13441 tacattttat aaaaagatta ttcattgatt ctatgattta caatagcttt agttttccaa
    13501 tgtcctttct tatagtagat aactgtaaca ataagaccta aagtccaacc aaaaggaata
    13561 cccatccaaa ttccgtctgt tccaaaaaat ttagaaagca tataagaagc tggaagtctt
    13621 ccaagccata aagatactat tgagcttata agtgcaaaca tggaatcacc agcacctttc
    13681 attgcacttg aaagtacaaa agaagttcca ataaataaga agaatggtcc tattataaat
    13741 aagtaagaag agccaatttt aatgacatct ttatcagtat tgaatagagc aattagattt
    13801 tccctaaata gcaaaattaa agcaataact gtaactgcta aaactaaggt catttttata
    13861 gattctcgaa tgcctttttt aactctttca ttttctccag cacctatgtt ttgagcaaca
    13921 aaagtagaaa cagcagaacc aagattcata ataggtaagc ttataaaatt ttctatccta
    13981 agaccagcac caaaagctgc catagcagat gtaccataac tattaactaa aaattgaaga
    14041 gccatatttc caattgaaaa caacatttgt tgaactccac ttggaagtcc taatctaagt
    14101 ccatctttaa atattttgtt atcatataca attcctttga ttttaaattt aagcacttca
    14161 tgttttttat ttaaataaat tatacttatt ataaatgata ctgcctgagc cattatagtg
    14221 gcaagtgcaa cgccctcaac acccattctt agcactacaa taaaagttaa gtctaaaact
    14281 atatttagaa ttgtggctat tatcagaaaa taaagtggag ttactgaatc tccaagtcct
    14341 ctaagtattg cacttactga attatatcca gcagaaaata atattccact aaatattata
    14401 gtaagataca attttgattg agcaaaaacg gattctggtg tattcataag cttaagcatt
    14461 gggccaccaa atactattcc aagaatactt attaatatag aaccaataaa taaaagtata
    14521 tatgtagtat caatagtagc ttttaccttt tttaaatctc ctgagccata aaattgtgac
    14581 actaaaatag aaaatccaag gctaacaccc ataagcgctg ccaccaataa aaacattata
    14641 gggttagctc cagagactgc cgccattgct tcttttccga taaatctacc aactattata
    14701 ctgtcagctg tattgtatag ttgttgaaat aaactaccaa taagcatagg catggcaaaa
    14761 aagaatatgg actttccctc atgacctgta gttaaatctt tcaccttatt cctccaaata
    14821 aaaaaattat taatttatta tagtataatc ttaacataaa ctttatatcc aaactataaa
    14881 taaattgtat caaaatatca tatatttttt taaaatgtaa agaatataat tataatttga
    14941 atttaataaa tcaatattta atataatcga atattaatac aaaatcaata caatatatac
    15001 gtatatattg acaaaattaa ttatataaat taaaataata ttcgtaaaga aaaattcatg
    15061 ttttgtactg tataacatat aattttgaca atatgggtca taagtttcta ccggaatacc
    15121 gtaaatattc tgactatgta tactattatt tagttaatta aatatttaat taactgaatt
    15181 atgaaggata cggctcagct tatcaactac tgtgtcgttt ttttgtaaaa tttaatagga
    15241 ggtgttgtta tgcaaacaac aaacagtagt actatgcaga aactttttcc aattttgact
    15301 aataaaaatg tcgacatgaa gaaggaaata attgcaggag taactacttt tttaactatg
    15361 gcttatataa tagctgtaaa tccaaatatt ttatctgaga caggcatgcc tgcaggtgca
    15421 cttgttacag gtacttgttt agcagcagca tttggatgta ttttaatggg tgtagttgct
    15481 aaccttcctt ttgctttagc atcaggtatg ggtcttaatg cattttttgc atatacagta
    15541 gttttacaaa tgggtgttcc ttgggaagta gctcttacag cagtatttgt agaaggtatt
    15601 atttttatag tattatcagt aagtggagtt cgtgaggctg ttgtaaatgc gataccaaaa
    15661 aatatgaaat tagctgttac aggtggtata ggaatattta ttgcacttat aggtctagtt
    15721 aacagtggaa ttgttattgg agaccaagcc actcttatca aaatgggtag atttacacca
    15781 gcagtaataa taacttgtgt aggattaata attattgctg tattagataa aaaaagagtt
    15841 aaaggttcta tactttttgg aatagtagtg agttcattac ttgcttgggc atttgctttt
    15901 ataaatccag agtatgcaca aaaattaggt atatatttac ctggtggatt atttaaattc
    15961 gaaagtttag caccaatagc aggtaaaata gatttaggat atgtactaca tccaacaaat
    16021 ataggtggtt ttttagtagt agtttgtaca tttttatttg ttgatttttt tgatacagta
    16081 ggtacattag ttggtgtttg ttctaaagca aacatgttag atgaaaaagg gaatgttcct
    16141 aatgtaggta gagccttact tacagatgcg gttgcaacta cagttggtgc aggacttgga
    16201 gtatctacag ttacaactta tgttgagagt tcaacaggag ttatcgcagg tggaagaact
    16261 ggatggacag caataacagt tggaatttta ttcttagctg caatgttttt ctctcctgta
    16321 tttatagcaa ttccatcatg tgctacagca ccagctttaa tatatgttgg atatttaatg
    16381 cttggtacag ttaaggatat agagtttgat aatataactg aaggtgttcc agcttttgtt
    16441 actattgctt gtatggcatt aacatatagt ataggtgatg gtttaacttt aggtatatta
    16501 acttatgttt tcgtaaatat attttataat atatttggag ctaaaaaggc agaagacaaa
    16561 aaacatgttt ctgtagtaat gattgttctg gcaatattat ttataataaa actttggcta
    16621 ctataatagg tattatttaa aattttaatt taatataaaa taaagggctg taatttatta
    16681 tcaattgtga tgataaacta cagctctttt gtatttgttg tatttttgta tttattgtat
    16741 tatttaataa tgtctattag ttctccattt tgtaaagttt taggtgtaat tactatattg
    16801 aactcttttt gcaaatcttt tataatatct aattcttttt ttgttattat tgagattgtg
    16861 ttaccacttc gatttcctct agcagttcga ccacatctat gcaggtattc atttttactt
    16921 tttggaaaat ccaagttaaa aacatgactt acatccacaa tatctagtcc acgagcagat
    16981 aaatcagttg taattaaaat ctttgcttta ccaagtttaa atttatttat tgcattcttt
    17041 ctatcttctt tttccatatt tccaaaaatt cctattgctt tgtaattatg ataatttagt
    17101 tttgatacta ggacttctat atttttttca ttatttacaa atacaatagc tttttttgga
    17161 tttgtagctg ctaatgcctt tctaagaaaa gtaaatttat cccttatctc acctaataaa
    17221 tatgagtgat tgatgttagg atttatttgt gatttttcct ttgtttttat tatttcaaac
    17281 tccttcataa gtttatcaca aatttttata gtgctatcag taagacttgc agagcatcct
    17341 ataatttgtc tatctcttaa cgttgttctt attatgtctt ctatacaagt tatatttttt
    17401 ccattcaata gattgtccac ttcatctaag ataatagttt ttatattatg tgattttagt
    17461 ttcttttgtt ttatcaagtc taaaactctt ccacaagagc caattactat gtgtggtttt
    17521 actgctttta tattttttat ttgtttttgt atattgacct ccccaattaa agctaaagaa
    17581 gtaacggaga gttctgcatt tttagccaat aattcaacct ggtttgtaat ctgcattact
    17641 aattcatgcg taggtgcaag tataagagct tgtgtttctc tttttgatgt atcaattttt
    17701 tcaaatatag gtaaaaggta tgctagtgtt tttcctgttc cagtctgtga attaatcaat
    17761 aaatccttat tttgaattat attccctata acaagtgact gaacttctgt tggagaagtt
    17821 atgtcttgtt ttttgagtcc atctattaga gtggaactta tttttaattg ttcaaatgta
    17881 ttcatatttt actccttata ttttaataat tatagtcaac tattttttat tatacattgt
    17941 ttattcaaat cgaactatat attcttttat aattatgtgt aatttgaaag taaatatcaa
    18001 ttatatttat acctttatat ttctgatacc tttgcatttt atagatttct aaaataaaca
    18061 aataaaagtt gtaattgttt gatatttgtt atatattata tataacaaat attaaaacta
    18121 taatatggag ggaaattatg ttaaaagtaa tcaatgtatc taaatcatat aaaaataaaa
    18181 aagtagtaag tagtgtctca tttgatgtaa atgatggaga gctttttggg tttataggac
    18241 ataatggagc aggtaaaact actactatta aagcaattgt tggaatacac gattttgaag
    18301 agggagaggt actaataaat tctaaatcta taaaaaaaca gcctgttgaa tgtaaaaagg
    18361 aaatggcata tatacctgat aatccagatt tatacgagtc attaactggt atacaatacc
    18421 ttaattttat agctgacata tttgaagttg ccaaagataa aagagaagag ttaataaaat
    18481 attattcaaa taagtttgaa ctcaataaag cattaggaga tttaatatct tcatattcac
    18541 atggtatgaa acaaaaatta gctataattt cggctttgat acacagccca aaaatcttaa
    18601 ttcttgatga accttttgta ggtcttgacc caaaagcttc ctttatattg aaggaaatta
    18661 tgagggagtt ttgtgacaaa ggtggttgta tatttttctc aacacacgtt ttagaagttg
    18721 ctgaaaaaat ttgtgataag attgccataa taaaagatgg aaatataatt gcttatggaa
    18781 ctacagaaga agttaaggga agtaattcac ttgaaagtat ctttatggaa ttaatagaga
    18841 aataaaatgt tttttataca atatagtgtc taaagtgagg aatgataaaa tatgagcaat
    18901 ctaagtatat taataaaaac taatataata aatgaattta aattaaatgc gttaaaaaaa
    18961 gctgatggta gagaaaaaca aaaaataatg ggaatgatgc tttcagttgt tataatagcg
    19021 ggtctattaa ttttttatgt aacaagctta agtctctctt tagttgatat cttaaagcaa
    19081 ataaatcaac tggaaatgct actgatattt ggttttggat tatcaacatt aacaactatt
    19141 gttacatcat tatataaaac gtcatcatat ctatttcaag caaaagattt agaccttttg
    19201 actagtttac ctataaaaga atctactgta ctagcaagta agatattaat gttggttgga
    19261 gcaaactatt tattttcttc aatatgtatg attatacctg cagtggttta ctttttaaat
    19321 tctgatgtaa gtataactta tttcccttat ttgatattgc tatttttagc tttaccatta
    19381 ttaccgatag ttgcttcatc aataattttt ctatttatag ggcagatatc atcaagaata
    19441 aaatacaaaa atttagtatt aatcataggt agcattatat tgatgttgct ttatacccta
    19501 cttatgtcaa gacttaattc tatgtcagtt gaaatgctaa agaatagtgt gtctatttca
    19561 gagacaatta gaaaagtata tcctcctata tattattttg ttgatgctct taaaacagga
    19621 agtatagttt catttttagc atttatagcc atctcaataa taccattttt tatgtttgta
    19681 actctatttg caaaaaaatt taaagatata aatgctaaga tgagtgaagg atataagtca
    19741 aaaaattatg aatttaaggg tcaaaaaact tcaagacctt caaaagcttt attaaaaaaa
    19801 gaatttaaga gatatacttc ttcgtttata tactttttaa attcatctgc aggtttgtta
    19861 tttctaatgg taggtacaat tttaatatta ttatttggag cagataaagt gggtgagtta
    19921 ctgaaattga atatagattt taatcttata aaaatacaat tattgggagt attcttcttt
    19981 ataatagtaa tgaattgtac aacatactgt tcaatttctc ttgaaggaaa aaacttatgg
    20041 atactgaaat cttctccaat agatgaaaga gaaatattct ggtcaaaaat attgatgaat
    20101 tttttattga atgcaccact atctatttta tgtctaatat tagtatctat aagattagac
    20161 tttgaaattc agtttattat tgtatcaatc tgtttgattg taagtttttc aatgtttgta
    20221 gcattgatgg gattattatc aaatttatta tacccaaacc ttgattggaa aaatgaggtg
    20281 gctgtagtaa aaagaagtgc aagtatgata gttacaatgt tagtatcatt agcttatgta
    20341 attatacttg gaggtatata tgtattactt ggaatttcgt ttttaaatat atatattatt
    20401 ttggcaagta tacttacttt gatattagat tttatgatat ggagaattat ttctactaaa
    20461 ggagtaagaa tatttaaaaa tttataggtg tatttatgtc aaataaagac ttatcttttt
    20521 tagtcttgca aataataggt taagtagtat actatgtata gtgatatgaa aaaatttagg
    20581 agaaaataaa tgagaaaatt atccaaaaga gaaaaagatt ttattcaata tggattttta
    20641 ttatttttga tatgtattac tacttattta gtattaacta ctttagatat aaaactaata
    20701 cctaaaatta taaggctagt aaataagact tatatatttc ttggcatatt gacaattata
    20761 gtatatatga taattgaatc tattgtaact catttgataa taaatgcagt tcaaaaaaca
    20821 aaagtaaaat ttattggtat taaaatggct acaatgggat tttactataa cttagttact
    20881 ccatttgcat ctgggagtca accaatgcaa atatatgcac ttacaaaata tgatgtaagc
    20941 cttagtaaat cagtggctat agttactaat aaaactgtag tatttcaaag tacagttact
    21001 gtattttgtg gaattttaat tttgctaaat aagtcattac tgatggagca agtacattct
    21061 gtgaaagtct tgataacttt tggaatgatt atgaatgtaa gtatgttgtt aggtggacta
    21121 ctaatagtat ttagtccaaa acaagtaaaa atgatagcag aagttttgat taatttttta
    21181 tctaaattta aaacatttaa atttttagat tcaaaacgtg atagaataaa tcattatatt
    21241 gatgattata attattctat aaaaatattt attaaaaatg taagaatctt agttttaagt
    21301 atattactta ctgtgttaca attaatcgca tatttcagta tagtttattg tgtgtataaa
    21361 gcctcaaatt taagaggagt ttcatatgta catataatga cattacaggt ctttttatat
    21421 atggctatat caccaattcc aacaccagga aatgttggag ctaatgaggt tacatttttt
    21481 actatgttct ccaatataat tccaaaagaa ttattggggt actctgtact cttatatagt
    21541 gggtttgtat actattttat attaatagtt tcaggtttat ttacatttgg aacgcattat
    21601 acattaaatt cttggaaaaa ggaaaataaa gtaaattcta atttagataa ggttattgaa
    21661 aaattaaatt aataaaataa ttagggaaat tctatatata aatatggtgt tgaataagct
    21721 atattatatt gagatatttc ccttttttga ttaaaattat agaaatttga aataataagt
    21781 aataaacaga aaaagtgata ttgttttgaa aggagaaact atgaaacaag ataaacaaaa
    21841 tgaaaaacaa agtgagattt ctaagataaa acaaagcaat gataataaac ttgaaatagc
    21901 tcaagaatta catgtaagta aaaatatagg gaatatgctt ggatatagaa tagataagaa
    21961 aaaaatgaat agaccaagtt aatgaaaatg ttgaaaatgg tacattttaa aaaatatata
    22021 taatgaaatg ttttattgtt aaatttaaac ttattttaat gggggaaaaa gtcgaaaaat
    22081 atctaaaaag atatggatat aaaaaatatt aatatatata tactataaac ttgacaaaat
    22141 caacctttta ataactagca aaaaatagca aaattatata agcgttattt aattgtcaaa
    22201 aatgaaagct aaattgcatg tcctaaaaaa aatgattgat aacatttatt tgtgtgctat
    22261 aattatatag taaaacaata agtatattgc ataatgtatg caaatcggga ggagagacgg
    22321 acatggaagc atctatacac acaattgcca gcaataattt attgataatt tttgctattg
    22381 taagtataac tggaataatt tgtagtaagc ttagtgaaat aataaaggtt ccagatgtag
    22441 tgttatattt acttgtaggt attttaatag gaccatcatt tttaaaattt atagatattc
    22501 gtggatttca aatagaaaat caactaatac ttacatttgg ttctgcattt attttatatt
    22561 taggtggaaa agaaataagt ttaaaagtat tgagaaatgt gaagatatct gtattcttat
    22621 tagctacttt aggagttgtg atatctgctt ttataatgca acaagtaata ggatttactt
    22681 ttgggataag tgcaatgact gctttactag caggaactat aatagcatca acagacccag
    22741 ccactcttgt acctatattt aatcaggtaa agataaagga tagggtaaaa caaactgtaa
    22801 taagtgaatc agcttttaat gatgcaacag gagctatact aacatcagca gtgttggctg
    22861 taattttgtc aaataaattt tcattaggtg aaaatattta tgaactgggg acaatggtta
    22921 ttgtcggagt tttagttggt ttaattacag gaatactgct tttgaaatta gttaatgata
    22981 aaccttatgg aatatttaaa gattttgcac caataatatc tgttatttca gttgtagttg
    23041 catatgaatt atctacaaaa ttaggtggaa gtggatatat gtcttgcttt attgtaggta
    23101 taataactgg taacaagaaa aattttaaaa tttggttaag tcaaaaatct tatgatgcag
    23161 atttttatgt tgctgaaact ttaggtacta tttgtcgtat ggcaatattt ataatattgg
    23221 gtagccaagt taatttggct cagttaagta aatattttat gccatctgta attacagtat
    23281 tagtattaat gtttatagca agaccacttt gcgttttagt ttgtacactt gtagacaggg
    23341 aagcaaaatg gagtaaaagt gaaatattat ttatgatgtg ggtaagggaa acaggcgtaa
    23401 taccagcagc actttgtggt attatttcag caatgaaagt tcctggatac gaagtgattt
    23461 catctgtagt attcatgact atactaatta cattagtaat acaaggaagt actacaaaat
    23521 tagtagctaa aaaacttgga ttattagaag aagaagtgat aaatataagt gaaaaagtat
    23581 caacttttta aagttttgct ttaaaatagt acctgttaat ggctatttta atattgtcta
    23641 atgatgatta ttgaaatagt cattttttta tgtataagta atttacagaa tttacatatt
    23701 agacatattt attatcaaaa tttgttgaag ctatgatata attagttgta tttaaaataa
    23761 gaatagcaaa taagggagga aatttatgtt tacggttatg gatattgtac agccagatac
    23821 agtagaagaa gcgtactcaa ttttaaataa aagaaaaact aaccaagtaa ttggtggaag
    23881 tgctttttta agaatgggga aaaaaagaat aggaacagga atagaattat ctaaattaaa
    23941 tttagattat ataaaagagt atgaagatta cgttgagatt ggttctatga ctacttttag
    24001 aacattagaa acaagttcca taataaaaaa taattttgga agaataatag aagattcagt
    24061 taaaaatata ataggagttc agtttagaaa tgtagtaaca gttggtgcaa cagtattttc
    24121 taaatatggt ttttctgact tgatagtagc attactttca ttagatacgg aagtagaatt
    24181 atataatatt gggagaatta gtcttgaaga gtttctaaat agagattatg agaaagattt
    24241 acttattaag atatacataa agaagacaaa taagaatgct tcttataaat caattagaaa
    24301 tgcaaagagt gattatccaa ttctaaatgt atctgtatca aaacatatgg aacaatttaa
    24361 gttatgtgta ggagcaagac cgcagaaagc tacgattgca aaacaagcta gtgaatttct
    24421 atctaacaat gaaatcaatg aaattaatat agataaagca gtagaaatag catcagaaga
    24481 actaactttt ggttctaaca tgagagcatc tagggagtat agaaaagcta tgagtaaagt
    24541 acttttaaaa agagctataa tggaggttat ttaatgttag taaagattaa tataaatggg
    24601 aagaaaaaaa gtgttgatat agaaccagaa gaatatctgg ttgatacttt aagaaaagtt
    24661 ggtaatttaa gtgtgaaaag aggttgtgac acaggttgtt gtggtttatg tacagtttta
    24721 attgacaaga aacctacatt atcttgtgca acactgacat tgagagcttt agataaagaa
    24781 ataactacaa ttgaaggttt agaaaatgaa gttaaagaat ttagtgaagt tttggtaaaa
    24841 gaaggagctg agcaatgtgg tttctgttct cctggcttta tacttactgt acttgcaatg
    24901 aaggatgagc ttgaaaatcc tacagatgat gaaataaagc attatcttac aggaaatcta
    24961 tgtagatgta cagggtatat gggacagtta agagctatca aaacttatct ggaggtaaaa
    25021 tagaacatga atatagttgg aaaaggaatc aagaaaatag atggaatgag tatcacaaca
    25081 ggaaagcctg tatatacaga tgatttatca gcaaaagatg ctttggtggt aaagatactt
    25141 agaagtcctc acgcttatgc aaaaataaaa gatatagata catcaaaggc agaaatggtt
    25201 gatggtgttg aatgtgtttt aacatataaa gatgtaccaa aatctcgatt tacacttgct
    25261 ggtcaaacat atccagagcc atctccatat gatagattaa ttcttgaaga tgttgtaaga
    25321 tatgtaggtg acgaagtagc tatagtggca gctatagatg aaaaaactgc aattaaagca
    25381 atgaatctta tcaaagtaaa gtatgaagta cttacacctg ttttggattt tgaagaggca
    25441 ataggaaata aaactatggt acatgatgaa gatagacatt gtaactttga tataggtatg
    25501 caaagagaaa aaaatatagt atcccatcat gattatacaa aaggtgatgt agaaaaagta
    25561 ttaagtaatt gtgatgtagt gattgaagaa acttattata ctcaagctca agcacatgca
    25621 atgatggaga cgtatagggc atacaattat ttagaccata tgggaagatt ggttgtagta
    25681 agttcaactc aaataccatt tcatgtaaaa agacatttat ctcgtgcact agaaatacca
    25741 gctagcaaaa ttagggttat aaaacctaga attggtggcg gatttggtgg taaacaaact
    25801 gcatgtgttg agattttttc tgcaattgtt actttaaaaa cagggaaacc agctaaaata
    25861 atttatgata gaaaagaaac ttttaattgt tcaacaagta gacatgcaat gagattaaaa
    25921 gttagactag gtgctacaaa tgatggcata ataaaggcaa tagatataaa agcactttct
    25981 gatacaggag catatggaga gcatgcttct acaactattg gtttggttgg agaaaaaact
    26041 ttaccaatgt ataataaagt tgaagcaaca agatttattg cagatgtggt atatactaat
    26101 aagatgccag caggagcact tagagggtat ggagcatcac aaggatgttt tgctgttgaa
    26161 tcaactataa atatgcttgc taataaatta aaaatggacc caacagattt aaggttaaaa
    26221 aatgtggtaa cagaaggtga aactacattt gcatatggta aaactttaaa tagtgtcgat
    26281 ttaataaaat gtataaataa aggcaaagaa cttattggat ggaatgaaaa atatccttgt
    26341 aaacatcttg ataatggaaa aattagaagt gtgggtatgg caattactat gcaaggttct
    26401 ggtatacaag gtcttgataa gtcttcagct gaaataaaat tgaatgactg tggagattat
    26461 actcttatga taggttctac tgatatgggt acaggaagtg atacaatttt agctcaaatg
    26521 gctgctgagg ttcttgatac aagcattgaa aatataacag ttatatcagc tgatactgac
    26581 ttagttccat atgacccagg ttcatatgct tcaagtacta cttatgtaac aggtatggca
    26641 gtagttaagg cagctcaaga cttaagagaa aaaataattt ctgctggagc aactaaacta
    26701 ggtgttgaga aggatgaagt agaatttgat ggtataaaat taactagtaa aaaaggtagc
    26761 actttattat tcgatatagc agttgattct acaattggtc cagatactaa tcaattaata
    26821 ggtcttgctt ctcatggtag cccagtatct cctccacctt ttatagcagg ttttgcagaa
    26881 actgaaattg acacagaaac tggaaaagtt gatttagtaa attatgtagc tgtagtagat
    26941 tgtggaacgg ttataaataa aaatctagct aagatacaag ttgaaggtgg aattgttcaa
    27001 gggattggaa tggcattatt tgaagaagtt agatacacag aaaaaggaag catggacaca
    27061 aatacattta tgcaatacaa gattccagct agatgtgata ttggaaatgt taaagtagat
    27121 tttgttgaaa cttatgaacc aactggacca tttggtgcta aatctgttgg agaagttgtt
    27181 ataaatacac ctttaccagc aatacaagaa gctgtgttta atggaattgg tgtaagaata
    27241 aatacactcc ctattacacc tgaaaaagtt tttatggaaa tgaataaata attatttatg
    27301 aaaatttaga ctagttttac atgttaaaca accagttatg tcatacctgt tgaaagatat
    27361 ttaataagta gttattataa tattatgaat tttacttata aaatacaaaa ttaaataagg
    27421 ggatgatgtt ttggctggta atctaaataa tatgagagca gtaaataatt ttagaggaga
    27481 taagaacatt ttagaatgtt tagtcagctt tgagggtcgt tcaataagtc agagaaaagt
    27541 aagggtattt tttaaagaaa aacaaaatca aatagaaatt gattttgcag aagaggaaat
    27601 ttctaaattg gttgaaaatg ttgttttaaa tacatcatat caagaaatgt tatatgatga
    27661 aatagagaaa caactggaaa ttgattgtat aggtacttgg atgatattat ctaaattaaa
    27721 agatggtagt agagttcact gattttaaaa taaattatta gagcctaatt ttaaggctct
    27781 tttttgctgt ttttaattaa caatagaaaa tttatcttta gtttgtatat aattttaata
    27841 tcatatattc tatatatata aaattgaatt tgtatgtatt atattgtata atataaaatg
    27901 aattgggaaa atagttcgct aaaataattt gtttttataa aattactgtt taagtttata
    27961 gattttgtat aaaataaagt tatgttatta atttttttaa aaataaaact tttactagga
    28021 gacagatatg agaaaaaata gtattaatat agcactaact gcagcaatta cagcaatcta
    28081 tgcagtttta acattatcat tgggatttat aagttatgga ccaatacaat ttagggtagc
    28141 agagattatg atgcttttgg catttttaga taaaggatat atagtaggtc ttacattagg
    28201 ttgtttttta gcaaatgtaa taggaccata tggtgtacct gatataattt ttggaacatt
    28261 agccacattt ataagtgcaa gtatgattta tattactaga aagttaggta aacaaaataa
    28321 aagtacttta gttatagctt ctttatggcc aactgttata aattcgattg tggttggtct
    28381 aatgttaaat gtattctttg ggcttccatt aattctatct atgatacagg taggttttgg
    28441 agaatttgta gtagtaacaa ttgtaggagt accatttttc tgctttttaa tgaaaaaata
    28501 taaaaatgtc attaatatta aattttaaat agtgtatagt aatttaatta attgagagta
    28561 ttattagtga aaagaggtgt ttatttgtcg aaggtaaaaa gattgactga tgtttggata
    28621 tatattaatg ataagcaaaa gtttacaata aaagagttgt cagaggaatt taatctttca
    28681 gctaaaacaa tacaacgata tttaaaagaa ttaaataaaa tgggacttcc aattcaagca
    28741 gaacaaggta gaaatggagg ttatagggtg ctaaataata gctatatacc tcctgttata
    28801 tttacagaaa aagaagttat gattatacta tttgcactta agtcacttca gatttataat
    28861 tataagttaa tggaaataga aattaattct ataatgagaa aagtaagtta tgaacgtaaa
    28921 agcagtataa aagtaggtat agaaaatatt aaaagataca ttggctttgt agctaatgat
    28981 actaatgatg gagattttaa gagtagtaat gtaactgagt tttttagagc ttcttcagaa
    29041 tctctaattt taaatattaa gtataagtgt ggtaatcaga ttttggaaaa aaacgtatgc
    29101 cctataggta tatatttaaa taagggagca tggttttcac cagcatatga ttgtaaaagt
    29161 gataaaataa tattagttca tatagataat ataattgata taaaaagaac aggagaaagt
    29221 aaaaaaatac atataaactt ggaagaatgg ttacatgaag tatataacaa tttatatgga
    29281 aatagttcaa ctactaaaaa atttggtgaa attatttatc taaatgtatt attaactaaa
    29341 gaaggtgttt ctaaaataaa ggacagttct tggaatttag atatggagct aaatgaagat
    29401 ggtagtggaa taattagtac attcataaag gttgaagata tagattgtta tgcttcgatt
    29461 ttatttttta ttggaaataa tgctaaggtt atagagccaa aatttttgaa taagctactt
    29521 tatgataagg ccaatgagtt aagatatttt tatgaagaaa atatggtata atatttagaa
    29581 atgttgaaat taaataatta ttaaggagat atacgttata atggaaaatt ttaataagaa
    29641 tgctaaaata attggtattg gagctgaagg tattaatata ataaatgaag tagaagaaaa
    29701 aataaaagca aatatggata tagaaaaaat aaacataaat caagagattg aaaaagaata
    29761 tgttagaagt cttttagatg gtgtagatat attatttttg atatattcat ctgaagataa
    29821 acatattaga gatattataa aagctgtttc atatatgtca aacgaaagaa gagttctatc
    29881 tataggaatg gattgttcag agaaggaaaa taaagaagat ttagagcttg ggagagagtt
    29941 taaaatcaat aatgatagta tatttaaatt tgttgattta atgaatatca tggtagagtc
    30001 tatttctgat tcttgcatga taaatataga tattactgat ttaaaagaag ctattgtagg
    30061 agataaagga attaagtatt cttttgaaga gtttgaagat acaaagtcat atagcgagat
    30121 agctgacatt ttatttgaca ggatggaata tattggtgag gaatttataa gtaagaaagg
    30181 aattgtattt gttgaaggaa gtccagaatt ttctataatg gaattgaatg atttaataag
    30241 taatattcag agcaaggtag aagaaagcta tgaagtaata ttttctttat atataaagga
    30301 aaatttaaat ggaaatatta gagtaggctt attgtataat tagtatattt tagatattaa
    30361 ggagagtgta tatgtctgaa aatataagag gtacagagta ttggttaatg gaagaatttt
    30421 tttatcagga aacagacaca ccacagattt ttagagaaga aagcataatt gcacttggat
    30481 ttgatataaa aataaattta aaaaaagtat tcagtatggg gaaaaaatca gaaaagtata
    30541 ttaatgagaa ttgtaatgat aaagatttta taaaaaagtt tatgtcgatt aaaaaaggag
    30601 attatttttt atataaagca tatcaaaata tagaagaaaa agttaaatgt aatgtgtcta
    30661 ttggcatagt tgaagaagat tttgaaaatg gatatgaatt aagtcatatt ttagggcata
    30721 cactaccagt aaaatggatg cataattttg atacagtttc aaattgtaaa gtatatacaa
    30781 gtgaatttta taaattaaat aataatgata ttagttcata tttagaaatt attaagtcac
    30841 aagataagaa attattgaga aaaagaatag aagaaagtga aaataataaa tggtatttaa
    30901 aaaactatta ttataaaaat gtagataagt gtgtagatga tgaagaatta tttattcagc
    30961 ccattaatct agaacaatta gaaagcctaa aaaatataaa gacagatgat tatattttat
    31021 tgtataatag cgagaaagta atttgtgaaa atgaccatac aatgaagagt ctatttggcg
    31081 tatgtcaagt tatggaaggg ttcgataaag agaaagtaag tgctttggag ggtggatatt
    31141 tttttcctgt tagatggata gagtatgaaa aggagaatat agacggaaat gcatgggtta
    31201 tatttgaaaa taatagtata gttgaaaagt atgtaaaaag atttactaat aaaatgccat
    31261 taaatactat actttatgga ccaccaggaa ctggtaaaac atacaataca aaacagatgg
    31321 tttacaatct agtaagtgaa accagtctaa gaaacagata ctatacaggt tacttagatt
    31381 ataaaaataa tgtagaattt tgtacatttc atcaatcata tggatatgag gaatttatag
    31441 agggccttaa gtctgatggt gaaggcaatt ttaagccaga agatgggata ttaaaggata
    31501 tatctataga agcatgttat aatgcattga aatttgaaaa aaagatgagc tttgagttgg
    31561 aaaaagatag cttgacttta gaaactataa aagacaggaa aaagaaatta gtattagaaa
    31621 atatagaata tagtgagagt tttaattttg aagaatcaga aaactatgtt ttaataatag
    31681 atgaaattaa tagagggaat gtatctaaaa tatttggtga gctaataaca ttattggaag
    31741 atgataaaag acttactaaa tcaaatcaaa ctattgtcaa actaccatat tcaaaggaaa
    31801 aattttctct acctccaaat ttgtatatag ttggaactat gaacacatca gataaatcaa
    31861 tagcactttt agatatagct ttaagaagaa ggtttaattt tgaagaaatt atgccagatt
    31921 atgatttatt gtctattgta gatggtatag atattagaaa aatgctatat acaatcaata
    31981 aaaggataga gtttttatat gatagagacc atgttattgg acaagcttat ctacttgctg
    32041 tagaaaatat taatgatata gtagtagtat ttagaagtaa aataatacca cttcttcaag
    32101 agtattttta ttatgattca gaaaaagtag gtttgatttt aggaggaatt ggaagaaatg
    32161 aaaaagataa atacattgtt tataaagaaa aacttatagc ttctgagtta tttaaaaata
    32221 ataatgcctc aataatggag agtaaagtta actattgtat aaaacaaaac atatctagtg
    32281 aggagctaaa aaatatatat gagtaaaaat atatatgtta aggaaaccta tgaatggata
    32341 aggataggta atggtgaaaa tgagcttaca gaaattgaat atgaaaaatt gcttaagtat
    32401 ctagagaaca ataatgatgt attaaaaagt aatataatag atattaaata caaaaaactt
    32461 agatttataa actatgtagg catcatatgt tttgaaaatg taatacttga aatacttcct
    32521 aaattgtcat taagtgataa tcttgtaaaa gatagagaga tactattaca gatgctttct
    32581 atatgtaata aaattccaat tacaatgaat gaaaaaataa gattgagttt gaaaaattat
    32641 aatctcttaa atttttttgt tatgtatttc attgagagta tgcaaacaca gatgaaaaaa
    32701 ggtatttatt ttgaatatat aaataaaata gagaacttaa atgttatgag gggtaaaata
    32761 ttattaagta catatgcaaa agaaaaaggc atttctccaa tgaaaataag atgtgaatat
    32821 gatgagtata gtgaaaataa tttcttgaat caagttctta aaaaagcatg tatatctatt
    32881 ttatgtagaa taaatgacaa ttcaattcaa ggcaagatta aaaaaatttt aagctatttt
    32941 caaaatgtag atttaattta tatagataga aaaaaactgt tggattataa attttataaa
    33001 aacaatgata gatttaaaga ttgttattta ctagctagac ttctactttt aaatttgtct
    33061 atggataata gtcaaaataa tcaagaggca ttttctatat tatttgaaat aaatactttg
    33121 tatgaagaat atataggaat tttaatcaaa agtatatggg acaattcatt tagagaaaca
    33181 tatatacaag ataagagtaa atttcttttg aaaaatgaac aaactggtaa gaaaaacttt
    33241 aatttaagac cggatatagt tttatatgac ttaaaaaatg aatatgaaat tataattgac
    33301 actaaatgga aagctattga agtagattca aatgtttttt ataggtcaag tgatatatac
    33361 cagatgtatg catatataac agcatatgaa aatgcaaaaa gatgtatatt attatatcct
    33421 tgtattcaaa aagataagaa ttatagttcc tggaaattat cagaatcatt taagggtaag
    33481 tttata
//
LOCUS       DAYAOO010000041        31440 bp    DNA     linear   BCT 12-OCT-2024
DEFINITION  TPA_asm: Clostridioides difficile isolate ST8-SSI-h139-18
            SAMN40601845-rid21577343.denovo.041, whole genome shotgun sequence.
ACCESSION   DAYAOO010000041 DAYAOO010000000
VERSION     DAYAOO010000041.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN40601845
            Sequence Read Archive: SRR28438827
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 31440)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 31440)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-MAY-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-MAY-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002157583.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002157583.1
            Genome Coverage       :: 163x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/11/2024 16:19:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 4,038
            CDSs (total)                      :: 3,963
            Genes (coding)                    :: 3,930
            CDSs (with protein)               :: 3,930
            Genes (RNA)                       :: 75
            rRNAs                             :: 6, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 60
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 33
            CDSs (without protein)            :: 33
            Pseudo Genes (ambiguous residues) :: 0 of 33
            Pseudo Genes (frameshifted)       :: 7 of 33
            Pseudo Genes (incomplete)         :: 25 of 33
            Pseudo Genes (internal stop)      :: 11 of 33
            Pseudo Genes (multiple problems)  :: 8 of 33
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..31440
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN40601845-rid21577343.denovo.041"
                     /isolate="ST8-SSI-h139-18"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Denmark"
                     /collection_date="2018"
                     /collected_by="Statens Serum Institute"
     gene            complement(131..610)
                     /locus_tag="ACGI5H_002146"
     CDS             complement(131..610)
                     /locus_tag="ACGI5H_002146"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905885.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2975 domain-containing protein"
                     /protein_id="HFG9697849.1"
                     /translation="MSNKLIKNLLSGILQILFFLLGLVIVAGGFKSFMYLCFSGEATL
                     QGTIYGILMFILGVSYFIIIKSLIEVLGSSEYSLFVKENVKRFRIIGYLLLLNSLIEF
                     ISTFGTTGKGMRFLDLGFGFYFTVPVFVYFITSLMSFVIADGFVKAIKIKEDNDLTI"
     gene            complement(905..1609)
                     /locus_tag="ACGI5H_002147"
     CDS             complement(905..1609)
                     /locus_tag="ACGI5H_002147"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454689.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="B3/4 domain-containing protein"
                     /protein_id="HFG9697850.1"
                     /translation="MKKFVIEDAFWNLFPSAKIGVVICNDIDNSIKDEDYKKIILKGE
                     EEALKYLEDSEFSNNQVIKVWREAFKKFKTKKGARSSIEALLKRVHNGNNIGTINPLV
                     DIYNFISLKYALPCGGEDIDKFIGDIRLTRAIGNEEFIPLGTDENSFPYEGEIIYKDD
                     GGAICRCWNWREAVRTMLTEDTNNAFLCIELVDESRFKEFENALNELAKIVQEKLGGN
                     CKISILDIDNKEVSVD"
     regulatory      complement(1673..1767)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00442"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="guanidine-I (ykkC/yxkD leader) riboswitch;
                     Guanidine-I riboswitches control genes whose products are
                     involved in modification or pumping out guanidine as a
                     toxic compound from bacteria; This is class of guanidine
                     riboswitches is based on the ykkC/yxkD leader; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /bound_moiety="guanidine"
                     /db_xref="RFAM:RF00442"
     gene            complement(1963..2979)
                     /locus_tag="ACGI5H_002148"
     CDS             complement(1963..2979)
                     /locus_tag="ACGI5H_002148"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430829.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transglycosylase domain-containing protein"
                     /protein_id="HFG9697851.1"
                     /translation="MGYYNDNDNNKIRRKKISNSKDSNKKSKHSYTPANKKNKSSKTS
                     SSKRMSEKVDSQNLIKRDRDSFTRDNVRPLNTDYNQRERRRVEYKQREKKLKSKKRKK
                     QKRIRIVRALLSIMLVALIIFSVAGAIFTVSAIKGSPEVTKKLIRSKYISSEVVSIKQ
                     MPNDLKHAIVSIEDERFYKHKGVDVISLVRSVLNNVFTDTTQGASTIDMQVSKNLLTS
                     NDKTMKRKIRDMYNAKQMNKIMTKDEILEAYLNNMYLGKNAYGAAKGAEVYFGKKVSE
                     LNLAECAMLAGMTNNPARYIDHGEAKKRQVIVLYKMHQLGYITDKEYRIAKADDTPFK
                     SEID"
     gene            complement(3107..3613)
                     /locus_tag="ACGI5H_002149"
     CDS             complement(3107..3613)
                     /locus_tag="ACGI5H_002149"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454691.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PolC-type DNA polymerase III"
                     /protein_id="HFG9697852.1"
                     /translation="MKEYVVVDLETTGLDPYKGCEIIEIGITEIKNEQIVKNYSRLIK
                     PKGIISSFITELTHISNEMVENEEPLELVLPRFRKYIGDRTIIAHNAKFDLKFLNYYL
                     RMLDLEPINNYICTVELLKKCKSYKGKNKKLETACAYYNIENINAHRADSDTLATAKL
                     FLKIKDEY"
     gene            complement(3772..4440)
                     /locus_tag="ACGI5H_002150"
     CDS             complement(3772..4440)
                     /locus_tag="ACGI5H_002150"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903182.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MORN repeat-containing protein"
                     /protein_id="HFG9697853.1"
                     /translation="MENITSYFTTILCVFICLSSVFIFTQLARVFINKKKINQKIKSR
                     NGFRYDRDFIEARREEIHIKDNNNNKNKSNNKKLKGEKVFKYDNGDLYKGEFVDGKKN
                     GFGIYIFSSKEKYEGLWKDDKMHGIGKYTYRDGSIYTGEFKYGLKNGLGKLTYPNNDI
                     YKGYFLDNKKNGKGVLYKNDGNKQAGIWEDDEQCKSLDFKDLNNNKINNVYQNRLNNN
                     KLKV"
     gene            complement(4853..5359)
                     /locus_tag="ACGI5H_002151"
     CDS             complement(4853..5359)
                     /locus_tag="ACGI5H_002151"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861543.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0010181 - FMN binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="flavin reductase"
                     /protein_id="HFG9697854.1"
                     /translation="MGFREVKIEELQFNPFTKIGKEWLLITAGDSEKFNTMTASWGGV
                     GVYWGKNVVTTYIRPQRYTKEFVDSNDTFTVAFFDETYREALNICGTISGRDINKIEK
                     AGLTPYFVDDTVAFEEANMIIVCKKLYHGNMPPENFDAKENDKKWYPEKDYHTMYISE
                     IIKVLVKE"
     gene            complement(5730..6758)
                     /locus_tag="ACGI5H_002152"
     CDS             complement(5730..6758)
                     /locus_tag="ACGI5H_002152"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893599.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004527 - exonuclease activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="exonuclease domain-containing protein"
                     /protein_id="HFG9697855.1"
                     /translation="MKRVYIDFEMNMPNSKSKRAVFNSDIIAIGAVVYDEKTKNIDKF
                     KSLIRPVSNEELYPHIQELTHISSEELKSAPSYEEVMRKFKKWLGIFSDIKGIYTFGN
                     LDLTCFNNTDMRSAKKNNHPRFVNNIRDLFVDIKEKYINCGMRCMNYISLKNLLEFVN
                     LEFSGDAHDPLNDAYNLFILDEAITNNVDIQNLLIIRDIIRPPFNDINSNLDNCFNKF
                     KESLYKKEGNYNIVDFSVEIIKTVRMYLLTIIDVNIQNLEIMKDISKKMDTIDKLKDI
                     EEGYFYLLEDVYFDMKDVLEDLMLYRMNEDEYKYEIKNIIKMFDEDLDNEKIYINKCN
                     NLNVVNKI"
     gene            complement(6806..7666)
                     /locus_tag="ACGI5H_002153"
     CDS             complement(6806..7666)
                     /locus_tag="ACGI5H_002153"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430834.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA 2-thiocytidine(32) synthetase TtcA"
                     /protein_id="HFG9697856.1"
                     /translation="MSELSGKGCEIIVPFEERLPVRDIEKSIIKKYRKNLWSKFMKAI
                     RDYKLVEEGDKIAVAISGGKDSILMAKMFQELKKHGQVNFDVEFIAMDPGYHANIRQL
                     LIDNCEYLNIPIHLFDSRIFEIADEIAKDYPCYMCARMRRGALYSKAEELGCNKLALG
                     HHYDDVIETTMLNLLCAGNFKTMLPKLNSTNFEGIKIIRPLYYIREEHIIRFIQNSGI
                     WPLNCACMVAAKKTGNKRYEIKDLIKSLESNFKNVEKSIFKAAENVNLDSVLGWQKDG
                     EKHSFLENFE"
     gene            7935..8144
                     /locus_tag="ACGI5H_002154"
     CDS             7935..8144
                     /locus_tag="ACGI5H_002154"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416732.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="spore coat associated protein CotJA"
                     /protein_id="HFG9697857.1"
                     /translation="MENKTRDIKKNCGPSLARPYINNQIFTEMYCLSDALKFGTIFPE
                     LNLLESEMYNKELYAKPKKYRGGRR"
     gene            8144..8410
                     /locus_tag="ACGI5H_002155"
     CDS             8144..8410
                     /locus_tag="ACGI5H_002155"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454698.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="spore coat protein CotJB"
                     /protein_id="HFG9697858.1"
                     /translation="MKDSSRAELMRKVQETSFACVDMNLYLDNHPDDKNAINTYNSLC
                     NQFAQARYAYENKYGPLTNFGYAPSRCPWQWADQPWPWDREFNY"
     gene            8439..9011
                     /locus_tag="ACGI5H_002156"
     CDS             8439..9011
                     /locus_tag="ACGI5H_002156"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416728.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="manganese catalase family protein"
                     /protein_id="HFG9697859.1"
                     /translation="MWIYQKTIQHPVNIKTCDPRMAKFLITQFGGPNGELAASLRYLS
                     QRYTMPTGNMRALLTDIGTEELAHVELICTMVYQLTSDASPEELKAAGLGSNYAQNGY
                     GIYPTDSNGVPFDVRPIAVMSNPVTDLHEDMAAEQKALATYYQLINLTDDVDVIDVLK
                     FLGQREIIHYQRFGEALMDAYELEESQKMF"
     gene            complement(9246..10436)
                     /locus_tag="ACGI5H_002157"
     CDS             complement(9246..10436)
                     /locus_tag="ACGI5H_002157"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454699.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SH3 domain-containing protein"
                     /protein_id="HFG9697860.1"
                     /translation="MNFNQKRIAASIMATAIIMPTMGNLAYANESEVESVSIESRTIT
                     GNAVNFRKGPGTNHESMGKLYKGDKVEYVGKEGSWVKVKYNGNTGYVHGNYVAINSLG
                     SSNESSDTSVKSTKVVTAKGLNFRTGPSTSSSKISTLGYGTEVGYISESNGWSKISSN
                     GRVGYVSSKYLGTSVNDSTNENAENSSNDLVKGTKVVTAKSLNVRTGPGTSHSKIATL
                     SYGTEVGSISESGGWTKVSYGNQTGYVSSQYLAEKGSVDTSIPSYSTNSPSQGADSVI
                     SFAKTLLGKPYVWGAEGPNSFDCSGFTQYVMKKSVGVSIPRVSRDQSKYGTYVNRGDL
                     RSGDLVFFDTQGSNNGSVSHVGIYIGNGDMIHASSGSSKKVTISNINSSYYSSRYVNA
                     RRVL"
     gene            complement(10696..11127)
                     /gene="dut"
                     /locus_tag="ACGI5H_002158"
     CDS             complement(10696..11127)
                     /gene="dut"
                     /locus_tag="ACGI5H_002158"
                     /EC_number="3.6.1.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454700.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000287 - magnesium ion binding [Evidence
                     IEA];
                     GO_function: GO:0004170 - dUTP diphosphatase activity
                     [Evidence IEA];
                     GO_process: GO:0006226 - dUMP biosynthetic process
                     [Evidence IEA];
                     GO_process: GO:0046081 - dUTP catabolic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="dUTP diphosphatase"
                     /protein_id="HFG9697861.1"
                     /translation="MYNLKVKKLNDDAIIPNFAHKGDAGMDLYSIEEVVIPPGETKLI
                     KTGICIELPTMTEAQVRPRSGLALKHSVTVLNTPGTIDEGYRGELKIILINHGKNDFK
                     VEKHMKIAQMIVKPIYDINIEEVKELSDSERGKGGFGSTGF"
     gene            11240..13468
                     /locus_tag="ACGI5H_002159"
     CDS             11240..13468
                     /locus_tag="ACGI5H_002159"
                     /EC_number="5.6.2.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861544.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003916 - DNA topoisomerase activity
                     [Evidence IEA];
                     GO_process: GO:0006265 - DNA topological change [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase"
                     /protein_id="HFG9697862.1"
                     /translation="MKLVLAEKPSVAKTIASFLGAKTRQDGYFEGNDYIITYAVGHLV
                     SLYDMKDYDKDKYSGSWKMNNFPFVPEDKFKFKIDSSKTKQFNTVKKLLNRKDVEYVI
                     NATDNDREGELIAFLIFLLAKNKKPVKRILVNEWTPEDITRGIKNLKDEDEMRNLQAA
                     GYTRLITDWLIGINFTSVATLKYGNGKLLNIGRVILPTVKLVYDRDMEILNFVPKTYY
                     EIEGHFKAEAGEYKGKYVKGKESKFDTLEDANKIIASITSETGKILDKKVTMSKEYAP
                     KLFSLTSLQGYITSKYSNFTSDKVLNVCQSLYEGNGKGGYITYPRTDSIFLEESLASK
                     ASQTLDKLKVGLEYENKIKFSKTKRVFDSSKVDSHSAIIPTYIIPKSLSKDEQLVYDA
                     IKDRFVANFMPPAEYENTEIKTEVDNCTFLTKGKVLKSKGYLEVYNKEEKNDLLPLVN
                     KDDVVDVLEIKPLTKQTTPPKPYTEDTLLKAMKNCGKNVPEEDTTVLSGYSIGTSATR
                     ADVLKKISQVGYVKKKGKSYSITDLGKNLVEIFPVKDLFDVDYTGKLEKSLSDIQKGK
                     YTRKEYLTNIISFIYQNVNIIKQDASKNINTEAYTFDSKTKKFTKTKEKKQKKDVTNT
                     EKEVAISKDSNNKKEVKNGDENQSLGKCPICQGDVLEFDKGFACKNHKECKFVIWKND
                     KYLSLYKKKVNKTMVKNILKKGETKVKSLTAKNGNKFDATLKYDKNPDTGYFNWKIEF
                     DN"
     gene            complement(13579..14064)
                     /locus_tag="ACGI5H_002160"
     CDS             complement(13579..14064)
                     /locus_tag="ACGI5H_002160"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454702.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family winged helix-turn-helix
                     transcriptional regulator"
                     /protein_id="HFG9697863.1"
                     /translation="MDNNNILKIADSFLDFLFVLENNIFKESDLLKKFQNNSDIMKAY
                     FEECPMAPSHAKVILYLMTSNSSSISQIASNLGILKSNMTPIIDRLVEHGLVNKFPDP
                     KDRRILRVELTDKAFKLFDAVKAILKESLVKKLSNLSEEELTLLDEHTLKLSEIVKKL
                     G"
     gene            14316..15539
                     /locus_tag="ACGI5H_002161"
     CDS             14316..15539
                     /locus_tag="ACGI5H_002161"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728791.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0005215 - transporter activity [Evidence
                     IEA];
                     GO_process: GO:0006810 - transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="efflux RND transporter periplasmic adaptor
                     subunit"
                     /protein_id="HFG9697864.1"
                     /translation="MKRYLIVFLMCSSLFLVGCGKTEESEPEKPIAVSVQKAIGGEIE
                     NTNSFSGTTKVKDETAVTAQTVGTVQEVYVKLGQNVRKGDELLSISSPELENSVKQSK
                     ASLDLAKASYSSATGGSLEAQVNQAKTALDNAKIQYEESQRNYDNNKILYEQEVISLD
                     QFKKIEFSLEQTKQQLDSAQRAYDTATSKSIPQAKALAKKQLDQAQVSYNLAMSNLDK
                     LTLTSPVDGTITAKNFDSKEMITQSQPAFIISNPSILEVDLNVAESDIGKFKKDGNVD
                     VIIEDQRILGKIDYVPSVVDPQTSLYPVKVLVNNTNNKFKAGMSAQVNLSVEKENGAV
                     TVPKKAIFEENGKKYVYIATKDNIAKKHLVQTGIVTEDKIEIKSGVSDKDTVIIGGIS
                     LISDGTKIFPVEKEK"
     gene            15543..18677
                     /locus_tag="ACGI5H_002162"
     CDS             15543..18677
                     /locus_tag="ACGI5H_002162"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416713.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="efflux RND transporter permease subunit"
                     /protein_id="HFG9697865.1"
                     /translation="MNLTQTSVKRPLTIIMVFLVLIVFGGIGYKKMSINLMPDIEIPV
                     VMVMTTWTGAGPQDVDEQVSQKVDESLSAVSNVKSTISSSQESVSMVVAQFEFGTNLD
                     EIMNDVRSKVDALQTSLPDDAAKPTVLKLDMNAQAIGQLVISGGNENSSQALRKYAED
                     VIQPKIESIDGVTSADLKGGKKAQVNVIADPAVLSNYGVSLSTIKGVLSSSNKTFPYG
                     SITQGEDKIVLRAIDKLESLDDIKQIQIPVKGGNTVRLDNLCSVDYGYADKDSIYRYN
                     GKDSLVIDISKQQDANTVKVMQSAYKYVDELNKENPQFKIKIANDTSSYISESINSVM
                     SNLLISAVIAFIVIFAFLKSVRASLVVAVAIPISIIGAIAILYFTGESLNLITASSLV
                     ISVGMVVDNATVVIENIFKYRKSGRLSLDDCAIEGTRTVTNAILASTLTTIAIFLPIM
                     FTEGIAKITFGALGKTLIASLAFSFIGAITLVPSVFAKLSRGKNSQKMQEKDSPIFDK
                     VSEAYKKLLSVCLRHQRLVVISSLLIFVASLFGMGFIGMDFMPAADKGELSISIELPK
                     GLSLESNDYYVSMTEKKVSDIPEIKTLITTLTSDSNNSKASIAIELESQKNRKRTTDE
                     IEKEIIDRVATVPDCKINVSQNSSVMGGAGGADFTLEMKGPDLDVLKILGKEAEKEFS
                     SIKGFRNVETSLTDTTQEAQFTIDKHKAQEYGVNTAEIAGMLRTAINGDSVTTATIDD
                     YKVDVNLKFKADTIDSLEDIKQLKVNSATGKEVPLGAFSDIKMADGLQSISRTDGDFS
                     VNITATLDNLDAGTATKLALEKTNKMVIPKDYSIGVGGETEMMNESMASLGFSMVIAI
                     ALVYMVMVAQFESFSKPFIIMFCVPFAFVGVVLSLLVSGQSLSTVGMLGIILLIGIVV
                     NNGIVLIDYIEQLRKTNRNNDLIGLVSIGCAARLRPVLMTTATTILGMLPTALSLGEG
                     GETMQPLAIVIMGGLTVSTLITLVLIPTIYLIFDKWENKFSDKMPKIFGKITDKIGSI
                     KRKIIKKPKLKAKV"
     gene            18699..20009
                     /locus_tag="ACGI5H_002163"
     CDS             18699..20009
                     /locus_tag="ACGI5H_002163"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893601.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0015562 - efflux transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TolC family protein"
                     /protein_id="HFG9697866.1"
                     /translation="MNKKMSKIVAIGCGVGIITANLIPVYADNNTSSINKVDNSILSD
                     SNKRTSEKEILTAREAVSAALKNSEKLKMKSEEIKMLKEKLEVQDEFDSFTGSDNSFP
                     YDQIGLLKNQSEQAKGFMEDQIANDITNKFNDLVSRENELDKIKNNLEIKTKEIKDMK
                     LKKDLGLVTSLETESAELELQTLQNTQKAKLQELKNNQDYFKLLTNIDLNNYQLDKEY
                     RFESFRVGGSVDSYMEGKVNEYLKYDQLILERTEESFNDKDENKADLPDRPNLTRPVA
                     PTKPEQGNLTDDEYKVLTDKYEKDYKRYEKEVEAYNLERQTYAAGLTTYANYLQQKFN
                     TENGLVTLEDSKKALKKGLIDSYAQLLALEDTIQITKKQLDLSEKQLKNTKLRYDLGL
                     ITLTDYKKQVVSNEDAKNSYDTLIVNYNSLKNGIEKPWILNTGK"
     gene            complement(20298..20543)
                     /locus_tag="ACGI5H_002164"
     CDS             complement(20298..20543)
                     /locus_tag="ACGI5H_002164"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890610.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc ribbon domain-containing protein"
                     /protein_id="HFG9697867.1"
                     /translation="MTKCPKCGKEVSSRPGSICPRCGFKVADESLKIRCPEPSCRALV
                     SRKLDYCPKCGCKLRGYNISEFVNMVRCKIDETFDKK"
     gene            complement(20757..23384)
                     /gene="ppdK"
                     /locus_tag="ACGI5H_002165"
     CDS             complement(20757..23384)
                     /gene="ppdK"
                     /locus_tag="ACGI5H_002165"
                     /EC_number="2.7.9.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861547.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0050242 - pyruvate, phosphate dikinase
                     activity [Evidence IEA];
                     GO_process: GO:0006090 - pyruvate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate, phosphate dikinase"
                     /protein_id="HFG9697868.1"
                     /translation="METKYVYSFGEGSKDMKSLLGGKGANLAEMTKIGLPVPPGFTIT
                     TEACNDYYVNNESIRAEIIKEIEEHLATLEKDLNKTLGCNKNPLLVSVRSGAVFSMPG
                     MMDTILNLGLNDNSVVGLAEATQNERFAYDSYRRFIQMFSDVAMEVPKYKFENVLDRV
                     KEAKGYTVDTELTTDDLKEIVKEFKAIYKKEIKNDFPQDPKEQLMLAIEAVFRSWNNP
                     RAIVYRKLNDIAHNLGTAVNIQSMVFGNMGETSGTGVAFTRNPATGENKLFGEFLMNA
                     QGEDVVAGIRTPQNISTLADVMPAVFDEFVKITHILEGHYKDMQDIEFTIENERLYIL
                     QTRNGKRTAAAAINVAVDLVEAGIIDEKEAIMRIEPNQLDQLLHPKFEDKALKEAKVI
                     AKGLPASPGAASGKVYFNADDVVKANEKGEKVVLVRLETSPEDIEGMVKAEGILTARG
                     GMTSHAAVVARGMGKCCVAGCGEIKVDEFNKEIRALDDVVIKEGEYISIDGSTGNVYL
                     GDVKKTEVSLTGNFEKLMNWVDKHKCMMVRTNADNPRDARAAIEFGAEGIGLCRTEHM
                     FFDEARLPAVREMILSNTVEQREKALEKILPMQREDFVELFKVMDGKPVNIRLLDPPL
                     HEFLPHDDETIEELSKSMGIKVSDIKKRIVDLDEFNPMLGHRGCRLAITYPEICVMQS
                     KAIIQGAIEAIKAGVKVSPEIMVPLVGEVNELKIIRKMIVETVDAIIKEEGIEVPYTV
                     GTMIEIPRACLTADEIAQEADFFSFGTNDLTQMAFGYSRDDAGKFLGQYVDEEILEKD
                     PFQVLDQNGVGKLVKMGAKLGREVKPELKLGICGEHGGEPSSVEFCYSVGLNYVSCSP
                     FRVPIARLAAAQASIKNPR"
     gene            complement(23445..24287)
                     /locus_tag="ACGI5H_002166"
     CDS             complement(23445..24287)
                     /locus_tag="ACGI5H_002166"
                     /EC_number="2.7.11.33"
                     /EC_number="2.7.4.28"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454708.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004674 - protein serine/threonine kinase
                     activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016776 - phosphotransferase activity,
                     phosphate group as acceptor [Evidence IEA];
                     GO_process: GO:0006468 - protein phosphorylation [Evidence
                     IEA];
                     GO_process: GO:0006470 - protein dephosphorylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate, water dikinase regulatory protein"
                     /protein_id="HFG9697869.1"
                     /translation="MLVKNLIIYAVSDSVGETAQQVAKACMSQFYVNETYEIKRFPYM
                     INKGVLLETLENAKAENALIVYTLVDEELCSIVERYCEREGLSCIDLMTDILREISKR
                     TGRKPKREAGIIRKLDESYFKRVEAIEFAVKYDDGKDPRGVLQADIILVGISRTSKTP
                     LSMYLANKNIKVANVPLVPEIPIPKEVFEIDTKKIIGLTNSPEKLNEIRTQRLKALGL
                     SSKANYANLERILQELDYSEEIMKRIGCPVINVSNKAIEETAGIILDIMKENGLKIYK
                     EIEI"
     gene            complement(24294..24932)
                     /locus_tag="ACGI5H_002167"
     CDS             complement(24294..24932)
                     /locus_tag="ACGI5H_002167"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416703.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HFG9697870.1"
                     /translation="MIIIQLNERQLKIIDIVKENEPITSESIASSLNVTRATLRSDLA
                     ILTMTGILDARPKVGYFYSGVSEINLIGKSVKEKTVEDIMSMPVLAKKDESIYDVIVT
                     MFLSDVGSIVIIDENEELCGVVSRKDLLKATIGGSDINKMPIGMIMTRTPNVVTLTKG
                     ASVLLASRKIIEHEVDSIPIVEYKGEDKNHMRVVGRISKTNITKLFLEIVDN"
     gene            complement(25368..26660)
                     /locus_tag="ACGI5H_002168"
     CDS             complement(25368..26660)
                     /locus_tag="ACGI5H_002168"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454709.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent oxidoreductase"
                     /protein_id="HFG9697871.1"
                     /translation="MLDLNRKLAKLEEEGKKIKVALIGAGHMGNGMVSQMANMKGIEA
                     SIVVDIDLELAHKAFTDAGIDEEIIDNVTNEKDAEIKLQEGKVLTCNDFLVACKTKSI
                     DVVIDATGGIAIGAEIALNSILNKKHIVMLNAETDCVVGPILKKLADDAGVIFTGSAG
                     DEPGAVMELFDFADAMGFEVRVIGKGKNNKLDLDCNPDTVREEAERKGASPHMIASFK
                     EGTKTMVEMALMCNATGFVPDVRGGHGIEATVNEVPKKYALKSEGGVLDNYGVVDFVN
                     GIAPGVFVVVAHKLKAVNDELKYLSMGDGPNYILYRPYHLCSLETPLSAAMAVLDHKA
                     TIVPKAGLVAEVMTIAKKDLKKGEFMDGYGAYTCYGTIEKYDVAKAMNAVPIGLISKK
                     TKVVKDIKKGEVITYDMVEIEKDTTLYHLRQLQEKIFG"
     gene            complement(26697..27053)
                     /locus_tag="ACGI5H_002169"
     CDS             complement(26697..27053)
                     /locus_tag="ACGI5H_002169"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430855.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucitol/sorbitol transporter subunit IIA"
                     /protein_id="HFG9697872.1"
                     /translation="MKYEVKISGIGSLVKELMDESNCLIIYDETINDDDLKDISVIHS
                     IATLKSDVEIGDTLTIGNRDYCIVSVGDIAQKTLREIGHCTIKFDGKCEVNLPGEIHV
                     EIGNPDITIGDLITIS"
     gene            complement(27088..27447)
                     /locus_tag="ACGI5H_002170"
     CDS             complement(27088..27447)
                     /locus_tag="ACGI5H_002170"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897605.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator GutM"
                     /protein_id="HFG9697873.1"
                     /translation="MKLLVILFVAYILNTIFIMKQNKLYFKTLNRAKKKGDIVSTGKK
                     KSYFSKGSIAVISSDSDGFIKFGEILKGRTVMAKFKEIEEIEGLDIYSAEQKFKDEES
                     IVQAIKFIKEKINVSFN"
     gene            complement(27516..29489)
                     /locus_tag="ACGI5H_002171"
     CDS             complement(27516..29489)
                     /locus_tag="ACGI5H_002171"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454714.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antiterminator"
                     /protein_id="HFG9697874.1"
                     /translation="MSVTEKIPSIDRKIFKILIMCSKKEFVSINSIANELNVTTRSVR
                     TYIKQLNKDLGNDIAVIKYIKGQGYKLEIKDEQILNKIIDMNRKNVFSLNSKEDRVEF
                     ILNYLIELDGFITLDSLADEMCVGRTTLVNDFQYVEKVLASYNLNLIKKQNTGMKLNG
                     NELDIRLFILNQLYKNSRKDFSNSKYFKGIKKEEIINLEEKLLTLFKKNNFYVTDEML
                     REVINYIVVLVYRVKEEKKVKDYDVKFDLLKSYDEYFIAREIKHIISGMFECTLNDEE
                     IIYLTIPLVSGNAPASECALNSSRISKNIDELMENIFNQIYVDMGIFINEDELRVGLG
                     YHLSFTLNRLLFNIKLKNVLLEEIKQNYILPFKLAQIAGKVIEKKYNLEVSEDEIGYI
                     AIHFSGYLERNSSRFYSIKKIAIICSTGLGTAKLLKIRVEKLIGNNPKIDTLSSFNLR
                     NINLDEYDIVFTTIDLDTSNINTIVLKINTIFDENKLREQLKTVLCLREGNIDTTNST
                     NLLINNLLDEDKFMILNEKTILASLEKMMDHLMDLGCIDEKFRKNIVNREEKSPTVFD
                     KGLLFPHSINEKSDKFLMAVGILEEPIEYANRSIKIILMTMFPCENKIDSDLLVKIYE
                     EVLKIGQDVKLTNKISKCRTFLEFKKVLLKNLI"
     gene            complement(29711..30724)
                     /locus_tag="ACGI5H_002172"
     CDS             complement(29711..30724)
                     /locus_tag="ACGI5H_002172"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430861.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucitol/sorbitol transporter subunit IIB"
                     /protein_id="HFG9697875.1"
                     /translation="MEENKILKIEKGTSGWGGPLYIKKEGNRNKILSMTAGGIHEVTL
                     KIKELLGCEIVDGFKTGVSDEEVAVVIIDCGGTARCGVYPKKKIPTINVNPVGKTGPL
                     AKFITEEYYVSDVNPNCISVVDGEDMPQKSQENKSENKSSIRKPDNYDEVKSKAQGEY
                     AKKNIILSIGQGAGQVVSKFYDAGRDTIQMVMNNVIPFMAFVSMLMGIILASGLGDWI
                     ARVISPLAGNIGGLLIISVICTLPFLSPILGPGAVIAQVVGTLVGTQIGLGAIPAYLA
                     LPALFAINGQAGCDFVPVGLSLGEAEPETVEYGVPALFYSRLITGPIAVIIAYGVAVF
                     ALR"
     gene            complement(30737..31282)
                     /locus_tag="ACGI5H_002173"
     CDS             complement(30737..31282)
                     /locus_tag="ACGI5H_002173"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430863.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucitol/sorbitol transporter subunit IIC"
                     /protein_id="HFG9697876.1"
                     /translation="MENVITGLSKGAEWFIGLFQKGGEQFIGLVSGTLPTLIVLMVAI
                     NSLIKIIGEERVNNWASKLGKNSFTRYILLPLVSVFFLGNPMCYTFGRFLKEEHKAGF
                     YDAAVSFVHPITGLFPHANAGELFVWLGISAGLTTLGKETTTLALWYFIVGLIVIFIR
                     GIVTEKMYAFLTRKNRATNKA"
BASE COUNT        10705 a         5214 c         3753 g        11768 t
ORIGIN      
        1 tattttagta ttataatctt ttaattttag cattatagtt tatgtattat accctaatat
       61 attttatttt aaattactag ttagtcactc ttttcgggtt atttatctcc tatatattaa
      121 agtgtcacat ctaaatagtt aaatcattat cctcttttat ctttattgcc tttacaaatc
      181 catctgcaat tacaaaactc ataagagaag ttataaaata tacaaatact ggaacagtaa
      241 aataaaatcc aaatcctaaa tctagaaatc tcattccttt tccagtagta ccaaaagttg
      301 aaataaactc aattagagag tttaaaagca aaagatatcc aataatccta aatcttttta
      361 cattctcttt tacaaatagg ctatattcag aactacctaa tacttctatc aatgatttta
      421 taatgataaa atatgataca cctaaaataa acattaatat tccataaata gtaccttgta
      481 gagttgcttc tccactaaaa cagaggtaca taaaactttt aaatcctcct gcaacaatta
      541 ctaatcctaa aagaaaaaat aaaatttgta atataccact tagtaaattt tttataagtt
      601 tattagacat catgccaact cctttaaaat attttatata tagtataata cattatatta
      661 tatcgttttt caataaaaat attataatta acaatatatt tttattgtta attatgcaaa
      721 taaaaaagag tataataaaa gcctttaaaa tacatttttt tcttatttta aaggcttttt
      781 atattctaca tttttatttt ctatattata tcctttgata atcgttatat ctaaaataga
      841 ccttcttacc ctaaatataa gtatctttat aactagaata gtccattaca acagcacctc
      901 catattaatc cactgatacc tctttattat caatatctaa aattgaaatt ttacaattcc
      961 cacccaattt ttcttgaact attttagcta attcatttaa agcattttca aattctttaa
     1021 atctactttc atctactaat tcaatgcata aaaaggcatt gttagtatct tcagtaagca
     1081 ttgttctcac tgcttcacgc caattccaac atctacaaat tgctccacca tcatctttat
     1141 aaattatttc tccttcatat ggaaatgaat tttcatctgt ccctagtggg ataaactcct
     1201 cattaccaat tgctctagtt agcctaatat ctcctataaa tttatctata tcctcccctc
     1261 cacaaggtaa tgcatatttt aatgagataa aattgtagat atccactaaa gggttaatag
     1321 ttcctatatt atttccatta tgaactcttt ttaataatgc ttcaatagaa gaccttgctc
     1381 cttttttcgt tttaaatttt ttaaatgctt ctctccatac tttaatcact tggttgttgc
     1441 taaattctga gtcctccaag tattttaatg cttcttcttc tcccttcaaa attattttct
     1501 tatagtcttc atcttttata gagttatcta tatcattaca aataacaact ccaatttttg
     1561 cactaggaaa tagattccaa aatgcatcct caataacaaa ttttttcatt agaaaacctc
     1621 ctcaaattta aaatatgtaa aaataaaaaa gcctatagaa atattcttaa atatctccca
     1681 ggcttttatc cttccgtgta cacaacaatt gcgcgttttc tcttggacct gaccattata
     1741 aaatgcggaa ccctagaaaa ctaaattata agttttttaa tttacaaaat acaattaaat
     1801 tttagcataa tatagcattt aagacaatat tctattatct agtttgtaca ttaaaacaat
     1861 ttgccattag attataatta tggtggcaaa tgggtggcaa atcacctttt ttattacatt
     1921 tttgtttgtt taaactattg aaaatactat attcttacaa ttttaatcaa tttctgattt
     1981 aaatggagtg tcatcagctt ttgctattct atactcctta tcagttatat aaccaagctg
     2041 atgcatctta tacagtacaa tcacttgtct cttcttagcc tctccatggt caatatacct
     2101 tgcaggatta tttgtcatac cagctaacat agcacactca gctaaattta attcactaac
     2161 ttttttacca aagtagactt cagctccctt tgcagctcca tatgcatttt tacctagata
     2221 catattattt aaatatgctt caagaatttc atccttagtc ataatcttat tcatctgctt
     2281 agcattatac atatccctta ttttccgctt catagtttta tcattactag taagcaggtt
     2341 ttttgaaact tgcatatcta tagtacttgc accttgtgtt gtatctgtaa acacattgtt
     2401 taatactgac ctaactagag aaataacatc tactccttta tgcttataaa atctctcatc
     2461 ttctatggaa actattgcat gttttaaatc atttggcatt tgttttatac ttacaacctc
     2521 actacttata tatttagacc taattaactt tttagtaact tctggtgacc cttttatagc
     2581 tgaaactgta aatattgcac ctgccactga aaatataatt agtgcaacta acataataga
     2641 taataatgct ctaactattc taatcctttt ttgttttttt ctttttttac tttttaattt
     2701 tttctctctt tgtttatact cgactcttct tctttctctt tgattgtaat ctgtatttaa
     2761 aggtcttaca ttatctcttg taaaactatc tctatctctt tttataagat tctgtgaatc
     2821 tactttttca ctcattcttt tactagaact tgtcttagaa cttttatttt ttttatttgc
     2881 cggagtataa gaatgtttag attttttatt actatctttg ctgttactaa tttttttacg
     2941 tcttatttta ttattatcat tatcattgta ataacccatt ttagtctccc ttcttcatat
     3001 aaggtacatt atacattgtt ctacaaaata aatcaaagaa caaaattgta agcttaaggg
     3061 tcaattttat aaaggatatt ttcactaatt ttctctatat ttataattaa tattcatctt
     3121 ttattttcaa aaatagtttt gcagttgcta atgtatcact gtcagctcta tgagcattta
     3181 tattctctat gttgtaataa gcacaagctg tttcaagttt cttgtttttt cctttataac
     3241 ttttacattt ttttaataac tctactgtac atatataatt gtttattggt tctaaatcta
     3301 acattctaag atagtaattt aaaaatttta aatcaaattt cgcattgtgt gcaattatag
     3361 ttctatcacc tatgtatttt ctaaatctag gtaaaactaa ttctagtggt tcttcatttt
     3421 ctaccatttc attacttata tgtgtcaatt ctgttataaa tgaagaaatt atccccttag
     3481 gttttatcaa ccttgaatag ttttttacaa tttgttcatt ttttatttct gttattccta
     3541 tttctattat ttcacaacct ttatatggat ctaatcctgt agtttctaaa tccacaacta
     3601 catactcttt catatctctt ctccttatta ttaaatggat atatttatat tctatattta
     3661 tgtaatagac taatcaatac ttaattttat atgatatagg aagattttac aaattacaac
     3721 atagatatat cctatattcc atcataaata aagatttttt tattagaata attaaacttt
     3781 taatttattg ttatttaatc tattttgata aacattattt attttattat tatttaaatc
     3841 tttaaaatct aaacttttac attgttcatc atcttcccat attcctgctt gtttatttcc
     3901 atcattttta tataatacac ccttaccatt tttcttatta tctaaaaaat atcccttata
     3961 aatgtcatta ttgggatatg ttaattttcc caaaccattt tttaatccgt atttaaattc
     4021 acctgtatat attgaaccat ctctataagt atattttcct attccatgca tcttgtcatc
     4081 tttccataat ccttcatact tttccttact tgaaaaaata tatatcccaa atccattttt
     4141 ctttccatca acaaactcac ctttatataa atcaccatta tcgtatttaa atactttttc
     4201 tccctttaat ttcttattgt tactcttatt tttattatta ttgttatcct ttatatgtat
     4261 ttcttctctt ctggcttcaa taaaatctct atcataccta aatccgtttc ttgatttaat
     4321 tttttgatta atcttcttct tattaataaa tactctagct agttgagtaa atataaatac
     4381 agatgataag catataaata cacatagtat tgttgtaaaa taactagtta tattttccat
     4441 aaaaaatcac cctttaaaaa atttatttaa aatacctaat ataatatata tttttattaa
     4501 atgttattta tacttttata gtactatatt gaataaaatt aactttgaaa ttatttacat
     4561 taaaataaat caaatacaaa tgccataaat taagtgtttc tagttagcat aaaaatactt
     4621 ataaagtata ctcaaatatt tcaaataaat acttttattc aaataaatct ctacttatat
     4681 aagtgcttat ataaataaaa agatgaacta tagtaaatat agttcatctt ttttataata
     4741 gtatttattt aaaattaata tttatttagt tactagcatc tacttagata tcagataaga
     4801 aagcacagtc atttacttat aataagttct tttcatatat tttttattat aattattctt
     4861 ttacaagaac ttttataatt tctgaaatgt acatagtatg gtagtctttc tctggatacc
     4921 attttttatc attttcttta gcatcaaagt tttctggtgg catattacca tgatatagct
     4981 ttttacatac tataatcata ttagcttctt caaaagctac tgtatcatcc acaaaatatg
     5041 gtgtaagtcc tgctttttct attttattta tatctctacc agaaatagta ccacaaatat
     5101 ttaaagcctc tctatacgtt tcatcaaaga aggcaactgt aaatgtatca ttactatcta
     5161 caaattcttt tgtatatctc tgtggtctta tgtaagttgt aacaacattt ttaccccaat
     5221 agactccaac accaccccag ctagcagtca ttgtgttaaa cttttctgaa tcaccagctg
     5281 ttataagtaa ccattctttg ccaatcttag taaatggatt aaactgtaat tcctcaattt
     5341 ttacttctct aaaacccatg acttcatcct acccttcatt ttttaattat ataaattaat
     5401 tgttaaaaat ttgaatatat gtactcttat aatactgact tttgattgtc ctacataatt
     5461 catgtaaatt ataatacaac aaatcaatta ctttcgcaat aagtagtttt catattttat
     5521 aagtgtaaaa tatagataaa atatattgat tataaagtat ataatatatt tttaaaccta
     5581 aagcaatata caataaaaaa atgtagaaag taagtatctc tctacatttt ttattgtata
     5641 ttatttttat attaatttaa ttttatcttg attcagtttt ataaaaaatt gttataattg
     5701 tcaagttcta ctctattatt tataatttct tatatcttat taacaacatt taggttatta
     5761 catttattta tatatatttt ttcattatct aagtcttcat caaacatttt tattatattt
     5821 tttatctcat acttgtactc atcttcattc attctataaa gcattaaatc ttctagtaca
     5881 tctttcatgt cgaagtacac atcttctaat aaataaaaat agccttcctc tatatctttc
     5941 aatttatcta tagtatccat ttttttactt atatctttca taatttctaa attttgtata
     6001 tttacatcta tgattgttaa taagtacatt ctcacagttt ttattatttc aacagaaaaa
     6061 tctacaatat tataatttcc ttctttttta tataatgact ccttaaattt gttaaaacaa
     6121 ttatctaaat tagaatttat atcgttaaat ggtggtctta ttatgtcacg tattattaaa
     6181 agattttgta tatctacatt atttgtgatt gcctcatcca aaataaataa attatatgca
     6241 tcatttaatg ggtcatgggc atctccacta aactctaagt taacaaattc aagtaaattt
     6301 ttcaatgata tatagttcat acatctcata ccacaattta tatatttttc ttttatatct
     6361 acaaataaat ctctaatgtt atttacaaac cttggatggt tatttttttt agcacttctc
     6421 atatctgtgt tattgaaaca tgtcaaatcc aaattaccaa aagtatatat tcctttaata
     6481 tcagaaaata tgccaagcca ttttttaaac tttctcatga cctcttcata acttggtgca
     6541 ctcttcaatt cttcagaaga tatatgtgtt aattcttgta tatgaggata caactcctca
     6601 ttacttactg gtcttattaa agatttaaat ttatcaatat tttttgtttt ttcatcatac
     6661 acaactgctc caattgcaat tatatcagaa ttaaatactg ctctttttga tttagaattt
     6721 ggcatattca tttcaaaatc tatatatact cttttcaata taaacaccct ttccaattgt
     6781 ttatagtgat tctttttaac tatttttatt caaaattttc taagaaagaa tgtttctccc
     6841 catctttttg ccaaccaagt actgaatcaa gatttacatt ttctgccgcc ttaaatatag
     6901 atttttctac atttttaaaa tttgattcta aactctttat taagtctttt atctcatatc
     6961 ttttattacc tgttttttta gcagcaacca tacatgcaca atttaatggc catataccac
     7021 tattttgaat aaatcttata atatgttctt ctcttatata ataaagtggt cttataattt
     7081 ttataccttc aaaattagta gaattaagtt taggaagcat tgttttaaaa tttccagcac
     7141 acaataagtt aagcattgtt gtctctatta catcgtcata atgatgacct aatgcaagtt
     7201 tgttgcaccc tagttcttct gcctttgaat ataatgctcc tctcctcatt cttgcacaca
     7261 tatagcatgg ataatctttt gctatttcat ctgctatctc aaatatcctt gaatcaaata
     7321 aatgtattgg tatatttaga tactcacaat tatctataag taattgtctt atatttgcat
     7381 gatatccagg gtccatagca ataaattcaa catcaaaatt aacttgtcca tgttttttta
     7441 actcttgaaa cattttagcc ataagaatac tgtcttttcc accagaaatc gctacagcta
     7501 tcttatcacc ttcttcaacc aatttataat ctcttattgc cttcataaac ttagaccata
     7561 aattttttct atattttttt attatacttt tttctatatc tcttactgga agtctttcct
     7621 caaaaggaac tataatttca cagccttttc ctgatagttc actcatctaa tcacctcgta
     7681 tatttatgtt aataatattt tacaaaaaag tctaccttca tccacaaaat actataattt
     7741 ttactttaat tttactaaat aatttatagt ttacaataac acataaactt ataataacat
     7801 aaataacctc tttcttttat tatctttttt atttttctca tttaatattt tattattagt
     7861 aacgattttt aaatgattga atattataca ctagatagag ttacctatct atttacaaca
     7921 aggaggtttt catcttggaa aataagacta gagatatcaa aaaaaattgt ggtccatctt
     7981 tggctagacc atacattaat aatcaaattt tcacagaaat gtactgcctt tctgatgcat
     8041 taaaatttgg aactatattt ccagaactaa acttactaga gtctgaaatg tacaacaaag
     8101 aattatatgc taagccaaaa aaatatagag gaggtagaag ataatgaaag actcatctag
     8161 agctgaactt atgagaaaag ttcaggaaac atcttttgca tgtgttgata tgaacttata
     8221 tttagacaat caccctgatg ataaaaatgc tatcaacact tataattcat tatgtaatca
     8281 atttgcgcaa gctagatatg cttacgaaaa taaatacggt cctttaacta actttgggta
     8341 tgctccaagt agatgccctt ggcaatgggc tgaccaacct tggccttggg acagagaatt
     8401 taattattag acatcaagta ttggaggatt gaaaattcat gtggatatat cagaaaacta
     8461 tacaacaccc agttaatata aaaacttgtg accctagaat ggctaaattt cttataactc
     8521 aatttggtgg gccaaatgga gaacttgctg catctttaag atatttaagc caaagatata
     8581 caatgcctac tggtaatatg cgtgcacttt taacagatat tggtacagaa gaactagctc
     8641 acgttgagct tatatgtact atggtttatc agttaacttc tgatgcaagc ccagaagagt
     8701 taaaagctgc aggtcttggt tcaaactatg ctcaaaatgg atatggaatt tatccaacag
     8761 attcaaatgg tgttccattt gatgtaagac ctatagcagt tatgtcaaat cccgtaaccg
     8821 atttacatga ggatatggca gctgaacaaa aagcacttgc aacttattat caacttataa
     8881 acctaacaga tgacgttgat gttatagatg tattaaaatt cttgggtcaa agagaaataa
     8941 ttcactatca aagatttggt gaagctttaa tggatgctta cgagttagaa gaatctcaaa
     9001 aaatgttcta aaatttttat ttgtataact attattattt gataatttat aatttactgt
     9061 tgtgttaaaa tttataaaaa atataaatat aatttatttt ctataaacag agaaaataaa
     9121 taaaaagcag gtatcaatca aatagtaaca tgtattatac tatacattac tatcaatatt
     9181 gtacctgctt tcatattata agcaataaag aaaaatctat ttattaggtt ttataataaa
     9241 aacaattata aaactcttct tgcatttaca tatctacttg aatagtagct actatttata
     9301 ttagatattg ttactttttt tgatgaacct gaagatgcat gtatcatatc tccatttcct
     9361 atgtatattc caacatgact tacagaacca ttatttgaac cttgtgtatc aaagaatact
     9421 aaatctccac ttctaaggtc tcctctattt acatatgttc catacttact ttggtctcta
     9481 gatactcttg gtatactaac tcctacagat tttttcataa cgtactgtgt gaatccagaa
     9541 cagtcaaaac tatttggacc ttctgctccc catacatatg gttttccaag tagtgtcttt
     9601 gcaaaactta ttacactatc agctccttga cttggagaat tagtcgaata agatggaatt
     9661 gaagtatcaa cagaaccttt ttcagcaagg tattgacttg acacatatcc agtttgattg
     9721 ccataactta cttttgtcca tcctccactt tcagaaatac ttccaacctc agtaccataa
     9781 cttaatgtag ctattttaga atgacttgta cctggtcctg ttctaacgtt caatgacttt
     9841 gctgttacaa cctttgtacc ctttacaagg tcatttgaac tgttttcagc attttcattt
     9901 gtagagtcat ttacactagt tcctaaatat ttacttgaaa cataacctac tctaccatta
     9961 gaacttattt ttgaccatcc atttgactca gatatgtatc cgacttcagt cccatatcct
    10021 agtgttgata ttttagaact acttgtactt ggtcctgttc taaaatttaa tccttttgct
    10081 gttacaactt ttgtcgactt aactgaagta tcactacttt cattgctact tccaaggcta
    10141 tttattgcta cataatttcc atgcacataa cctgtgtttc cattatattt aacttttacc
    10201 caagaacctt cttttcctac gtactcaact ttatcacctt tgtaaagttt ccccattgat
    10261 tcatggtttg tacctggtcc ttttctaaaa tttaccgcat tccctgttat tgttctgctt
    10321 tctatactca cactctctac ttcagactca ttagcatatg ctaaattccc catagtaggc
    10381 attattatcg cagttgccat tatactggct gctattctct tttgattaaa attcataact
    10441 ttccactcat ctcctctttt ctactatctt tatttcactt caaaatataa aagaaataat
    10501 tgacactatt aaaatatcaa ttatttcttt tatattaata ttattacaaa tttgtaacta
    10561 tttgtctata gtaatatttg cttaccataa attaccatgt ataaatttta atctttaata
    10621 gcctgtaatt tagtaatata gccatctttt acctttttta aaaatggcta tattttttaa
    10681 cttttttgta actttttaaa atccagttga gccaaaccca ccttttcctc tttcggagtc
    10741 acttaattct tttacttctt ctatgttaat atcatagata ggttttacta tcatttgagc
    10801 aattttcata tgcttttcaa ccttaaaatc atttttacca tgatttatta atataatttt
    10861 aagctctcct ctgtatcctt cgtcaatagt tcctggtgta tttaatacag taacagaatg
    10921 ctttaaggca agcccacttc taggtcttac ctgcgcttct gtcatagtag gaagctctat
    10981 acatatccca gttttgataa gtttagtctc tccaggaggt attacaacct cttctataga
    11041 atacaaatcc ataccagcat cacctttgtg agcaaaatta ggtattatag catcatcatt
    11101 taattttttt acttttaaat tgtacatctt atatctcctt tcaactttct ataaatatta
    11161 taacttaaat ttcgacctct tgaagttttt tatttttttg tggtaatata attattagtg
    11221 ttttaaagga ggatttttta tgaaacttgt acttgctgag aaaccatctg tggcaaaaac
    11281 tatagcatca tttttaggtg caaagaccag acaagatggt tactttgaag gaaatgatta
    11341 tataattact tatgcagttg gacacttagt atcattatat gatatgaagg attatgataa
    11401 agataaatac tctggctctt ggaaaatgaa caatttccca tttgttcctg aggataagtt
    11461 taaatttaag attgatagtt ctaaaactaa acaattcaac actgtaaaaa agcttttgaa
    11521 tagaaaagat gtagaatatg taataaatgc cactgacaat gaccgagaag gagaacttat
    11581 agcattttta atatttttac tggcaaaaaa taaaaaacca gtaaaaagaa tcttggtaaa
    11641 tgaatggaca ccagaagata ttacaagagg tataaaaaac ctaaaagatg aagatgaaat
    11701 gagaaatctt caagctgctg gatatactag gcttattact gactggttga ttggaataaa
    11761 tttcacttct gttgctacat tgaaatatgg aaatgggaaa ctattaaaca taggtagggt
    11821 aattcttcca acagttaaat tagtctatga tagagatatg gaaatactaa actttgttcc
    11881 taaaacctat tatgaaatag aagggcattt taaagctgaa gctggtgaat ataaaggtaa
    11941 atatgttaag ggtaaagaaa gtaaatttga tacacttgaa gatgcaaata aaattatagc
    12001 ttcaattaca tctgaaactg gtaaaatact agataaaaaa gttactatgt caaaggaata
    12061 tgcaccaaaa ctttttagtt tgacatcact tcaaggatat ataacttcta agtattccaa
    12121 ttttacatct gataaggttt taaatgtctg tcaatctctc tatgagggta atggtaaggg
    12181 tggatacata acttacccta gaactgattc cattttctta gaagaaagtt tggcttcaaa
    12241 agcttctcaa actttagata aattaaaggt tggtcttgaa tatgaaaata aaattaaatt
    12301 ttctaaaact aaaagagttt ttgattcttc taaagtagac tcccatagtg ctataattcc
    12361 aacttatata attccaaaaa gtttatctaa ggatgaacaa ttagtttatg atgccataaa
    12421 agatagattt gtagcaaact ttatgcctcc tgctgaatat gagaatacag aaattaagac
    12481 tgaagtagat aattgtactt tcttaacaaa aggtaaggtg cttaaatcaa aaggatacct
    12541 tgaggtatat aataaggaag aaaaaaacga tttacttcca cttgtaaata aagatgatgt
    12601 tgtagatgtg ttagaaataa aaccattaac taagcaaact actccaccta aaccatatac
    12661 tgaggacaca cttttaaagg ctatgaaaaa ttgtggtaaa aatgtgcctg aagaagatac
    12721 aacagtgcta tctggatatt cgattggaac atcagccaca cgtgctgatg tgttaaagaa
    12781 gataagtcaa gtgggctatg taaagaaaaa aggtaaatct tattctataa cagaccttgg
    12841 gaaaaattta gttgaaattt ttcctgttaa agacttattt gatgtagatt atactggaaa
    12901 acttgaaaaa agtttaagcg atattcaaaa aggaaagtat acaagaaaag aatatcttac
    12961 taatatcatt agttttatat atcaaaatgt caatattata aaacaagatg cttcaaaaaa
    13021 tataaacaca gaagcatata ctttcgattc aaaaactaaa aaatttacta aaacaaaaga
    13081 aaaaaaacag aaaaaagatg taactaatac tgaaaaagaa gttgctatat caaaggattc
    13141 taataacaaa aaagaagtta aaaatggtga tgaaaatcaa tctcttggca aatgccccat
    13201 ttgtcaaggt gatgtactag aatttgacaa aggctttgct tgtaaaaatc ataaagaatg
    13261 taaatttgtt atttggaaaa atgataagta tttaagtctt tataaaaaga aagttaacaa
    13321 aacaatggtc aaaaatattt taaaaaaagg tgaaactaaa gtaaaatctt taactgctaa
    13381 aaacggtaat aaatttgatg ctacattaaa atatgataaa aatccagata ctggctattt
    13441 caattggaaa atagagtttg acaactaaat attcataaga aaagaaatag cagtagtata
    13501 ataatctata ttatattact gctatttctt ttcttatgaa gttttaactt ttttaatagt
    13561 gacttttaca atcacactct aacctaattt ctttactatt tctgataact ttaatgtatg
    13621 ttcatctaat aaagttagtt cctcttcaga aagattagat aattttttta ctagagattc
    13681 tttgagaata gcttttactg catcaaataa tttaaatgct ttatctgtta attcaaccct
    13741 aagaatcctt ctatcttttg ggtcaggaaa tttattgact aaaccatgtt ccactaatct
    13801 gtcaataatc ggagtcatat ttgattttaa aattcctaaa ttagaagcta tttgagaaat
    13861 tgatgatgaa tttgatgtca taagataaag aattacctta gcatgtgatg gagccattgg
    13921 acattcttca aaataagctt tcattatatc agagttattt tgaaactttt ttaacaaatc
    13981 gctttcttta aatatattat tttcaagcac aaataaaaaa tctaaaaaag agtccgctat
    14041 tttaagtata ttgttgttat ccatatttgt aacatccctt caatagataa tataataaaa
    14101 cattgttgtt taatatagta taaattataa actattaata aatttaaaac aagaaaaagt
    14161 tattgactca taataattat aaatttataa tcaaattaga gaattataaa ttgccaataa
    14221 agggaagttt tttaattagt ctaaaactaa acttaaatta taagacactt taaattctac
    14281 aacaagctag tgtgcaatat ataataggag gagatatgaa aagatattta atagttttct
    14341 taatgtgtag ttcactgttt ttagttggat gtggaaaaac agaagaatct gaacctgaga
    14401 aaccaatagc agtttctgtt caaaaagcaa taggtggaga aattgaaaac acaaattctt
    14461 tctcaggaac tacaaaggtt aaagatgaaa cagctgttac tgcacagact gttggcacag
    14521 ttcaagaagt gtatgtaaaa cttgggcaaa atgtaagaaa aggagatgaa ttattgagta
    14581 taagcagtcc agagctagaa aatagtgtaa agcaaagtaa agcctcacta gatttagcaa
    14641 aagcaagtta ttcaagtgcc actggtggtt cattagaggc acaagtaaat caggcaaaaa
    14701 cagctcttga caatgcaaag attcaatatg aggagtctca aagaaattat gacaataata
    14761 agattcttta tgaacaggaa gtcattagtt tagaccaatt taaaaaaata gaattttctt
    14821 tagagcaaac aaaacaacag ttagattctg ctcaaagagc atacgataca gcaacttcaa
    14881 aaagtatacc tcaagctaaa gcacttgcta aaaaacagct tgaccaagct caagtatcat
    14941 ataatttagc aatgagtaat ttagacaaat taacattaac atctccagta gatggtacaa
    15001 taacagctaa aaactttgat tcaaaggaaa tgataacaca atcacaacca gcttttatta
    15061 tttctaatcc tagtatacta gaagttgatt taaatgtagc agaatcagat ataggtaaat
    15121 ttaagaaaga tggaaatgta gatgttataa ttgaagacca aaggatttta ggaaaaatag
    15181 attatgtacc ttcagtagtt gaccctcaga catctttata tcctgttaaa gtacttgtaa
    15241 ataatacaaa caacaaattt aaggcaggta tgtctgctca agtaaactta agtgttgaaa
    15301 aagaaaatgg tgctgttaca gtacctaaaa aagcaatatt tgaagaaaat ggtaaaaaat
    15361 atgtatacat agcaacaaaa gacaatatag caaagaaaca cttggttcaa actggaattg
    15421 taacagagga taaaatagaa attaaaagtg gtgtaagtga taaagataca gtgattattg
    15481 gagggataag tcttatttct gacggaacta agatatttcc tgtagaaaag gagaagtaga
    15541 ctatgaattt aacacagact tccgttaaac gtcctctcac aatcataatg gtctttttag
    15601 tattaatagt ttttggtggt attggatata aaaaaatgtc aataaatcta atgcctgata
    15661 tagaaatacc agttgtaatg gtcatgacta cttggacagg tgctggtcct caagacgttg
    15721 atgaacaagt tagtcaaaaa gttgatgaaa gtttatctgc cgtttcaaat gtaaaatcta
    15781 ctatatcaag ttcacaagaa agtgtttcta tggtagttgc tcagtttgaa tttggaacta
    15841 atttggatga aataatgaat gatgttaggt ctaaagttga tgcattacag accagcctcc
    15901 cagatgatgc agctaaacca acagttttaa agctggatat gaatgcacag gccataggtc
    15961 aacttgtcat atctggagga aatgaaaata gttcacaagc cttaagaaaa tacgctgaag
    16021 atgtaattca gcctaaaata gaatccatag atggtgttac ttcagcagac cttaaaggtg
    16081 gaaaaaaagc acaggttaat gtaatagctg acccagctgt tctttcaaat tatggggtta
    16141 gtttatccac tataaaaggt gtcttatcct ctagtaataa aacattccct tatggttcaa
    16201 ttactcaagg tgaggataaa atagttttaa gagcgattga taaattagaa tccctagatg
    16261 atataaaaca gattcaaatt cctgtaaaag gaggaaatac agttagatta gataatcttt
    16321 gtagtgtaga ttatggatat gcagacaaag atagtattta tagatacaat ggaaaagaca
    16381 gtttggtaat agatatttct aaacaacaag atgccaacac tgtaaaagtt atgcagagtg
    16441 catacaaata cgtagatgaa ttgaataagg aaaatcctca atttaaaatt aaaattgcta
    16501 atgatacaag ttcatacata agtgaatcaa taaacagtgt aatgagcaac ttgcttataa
    16561 gtgctgttat cgcatttatt gtaatatttg ctttcctaaa aagtgtaaga gcttcactag
    16621 ttgttgcagt tgcaatacca atttctataa taggtgctat agcaattctc tactttactg
    16681 gtgaaagttt aaatcttatt actgcaagtt cattggtaat ttcagttggt atggttgttg
    16741 ataatgctac agttgtaatt gaaaatatat ttaaatatag gaaaagtggc agattgagtc
    16801 ttgatgattg tgctattgag ggaacaagaa ctgtaacaaa tgcaatactt gcatcaacat
    16861 tgaccacaat agcaatattc ttacctatca tgtttacaga aggtatagct aaaataactt
    16921 ttggggcatt aggtaaaaca ctaatagctt cactagcatt ctcctttata ggtgcaatta
    16981 cactcgttcc tagtgtattt gcaaaattaa gcagaggaaa aaatagtcaa aagatgcaag
    17041 aaaaagatag tcctatattt gataaggtaa gtgaagcata taaaaaatta ttaagtgtat
    17101 gtttgagaca tcaacgctta gttgtaatat caagtttact tatttttgta gcttccttat
    17161 ttggaatggg atttataggt atggacttta tgcctgcagc agacaagggt gaattatcta
    17221 tttctataga acttccaaaa ggtcttagcc tagaatccaa tgattactat gtatctatga
    17281 ctgagaaaaa agtctcagat attccagaaa ttaaaacttt aataacaact ttgacatcag
    17341 attcaaataa tagtaaagca agtatagcaa ttgaattaga atctcaaaaa aatagaaaaa
    17401 gaactactga tgaaatagaa aaagagataa ttgatagagt ggctactgta ccagattgta
    17461 aaataaatgt aagtcaaaac agtagtgtta tgggtggagc tggaggagca gacttcacat
    17521 tagaaatgaa aggtcctgat ttagatgtat taaaaatact gggaaaagaa gctgaaaaag
    17581 aatttagctc tataaaagga tttagaaatg ttgaaacttc tcttacagat acaacacaag
    17641 aagctcaatt tactatagat aaacataagg ctcaagaata tggtgtaaat accgctgaaa
    17701 ttgcaggcat gttacgtaca gcaataaatg gtgactccgt aaccactgct actattgatg
    17761 attacaaagt ggatgtaaac ctaaaattta aagcagatac tattgatagc ttagaagata
    17821 taaagcaact aaaagtaaac tctgcaactg gaaaagaagt tcctcttggt gctttttcag
    17881 atataaaaat ggcagatggt ctacaatcta tatctaggac tgatggagat ttttctgtaa
    17941 atataactgc tacacttgac aatttagatg ctggtactgc tacaaaacta gcactagaaa
    18001 aaacgaataa aatggtaatt cctaaagatt actctatagg tgttggtggt gaaacagaaa
    18061 tgatgaatga atctatggca agtcttggat tttcaatggt catagctata gcattagttt
    18121 atatggtaat ggtagctcag tttgaatcat ttagtaaacc atttataatc atgttctgtg
    18181 ttccatttgc attcgttgga gttgtgcttt cgcttctagt tagtggtcaa agtttaagta
    18241 ctgtcggtat gctaggtata atcttactta tcggtattgt tgttaataat ggtatagttc
    18301 ttattgacta catagagcaa cttagaaaaa caaatcgtaa caatgattta attggtttgg
    18361 tttcaattgg ttgtgcagca agattaagac cagtcttaat gactacagca acaacaattt
    18421 taggtatgtt gccaacagca ctatctcttg gtgaaggtgg agaaactatg caaccactag
    18481 ccatagttat aatgggtggt ctaactgtat ctacacttat aactttggtg cttataccta
    18541 ctatatactt aatatttgat aaatgggaaa ataagttttc agacaaaatg cctaaaatat
    18601 ttggtaagat aacagataaa ataggaagta taaaacgtaa aataataaag aaaccaaaat
    18661 tgaaagctaa agtttaaata gaatggaggg tgattgtatt gaataaaaaa atgagcaaaa
    18721 tagttgcaat tggctgtggt gttggtataa taactgccaa tttaatccca gtttacgcag
    18781 ataataatac ttcttctata aacaaagttg ataattctat tttaagtgac tcaaataaaa
    18841 gaacatctga aaaggaaatt ttgactgcta gagaagctgt tagtgctgca cttaaaaata
    18901 gtgaaaaatt aaaaatgaaa tcagaagaaa taaaaatgtt aaaagaaaag ttagaagtac
    18961 aagatgagtt tgatagtttt actggaagtg acaactcgtt tccatacgac caaattggac
    19021 ttcttaaaaa tcaaagtgaa caggctaaag gctttatgga ggaccaaata gcaaatgata
    19081 ttactaataa atttaacgat ttagtttcaa gagaaaatga gctagacaag ataaaaaaca
    19141 atcttgaaat aaaaactaaa gaaattaaag atatgaaatt aaaaaaagat ttagggttag
    19201 taacatcttt agaaactgaa tcagctgaac ttgaacttca aacactacaa aatactcaaa
    19261 aagctaaact tcaagaacta aaaaacaatc aagactactt taagttgttg actaatatag
    19321 atttaaataa ttatcaattg gataaagaat atagatttga atcttttaga gtaggtggct
    19381 cagttgattc atatatggaa ggtaaggtta atgaatattt aaaatacgac caattgattt
    19441 tagaacgtac agaagaaagc tttaatgata aagatgagaa caaagcagat ttaccagata
    19501 gacctaatct tacaagacca gttgctccta caaaaccaga gcaaggtaac ctaactgatg
    19561 atgaatataa ggttcttacg gataagtatg aaaaagacta caagagatat gaaaaagaag
    19621 ttgaagcata caatcttgaa agacagactt atgctgctgg ccttactact tatgcaaatt
    19681 atcttcaaca aaaatttaat accgaaaatg gtctagtaac attagaagac agtaaaaaag
    19741 ctcttaaaaa agggttaatt gatagctatg ctcaattact tgctttagaa gatacaattc
    19801 agattactaa aaaacaactt gatttatcag aaaaacaatt aaaaaatact aaattaagat
    19861 atgatttagg attaattact ctaactgatt ataaaaaaca agtggtaagt aatgaagatg
    19921 ctaaaaatag ctatgacact cttattgtga attataactc actaaaaaat ggtatagaaa
    19981 aaccttggat acttaatact ggaaaataat tctggtaaat agaaagatta ctttaacata
    20041 cgtttgatta aaaaatagtt atgcacactc gtggctttag tcatggaaga ttcagaaggc
    20101 aaataataga aatagattag taaaaatata tttgcttata aaactgtata attttataga
    20161 ggctatctca aaatagagat aagcctcttt tttattgttt aaattataaa aatatattta
    20221 attccataca aaaagagtgc cttatgaact aaaaagttca ttttgagaca ccctcaaaag
    20281 cttaactcta aatttaatta ttttttatca aatgtctcat ctattttaca tctcaccatg
    20341 ttaacaaatt cagaaatatt atatcctcta agtttgcatc cacatttagg acaataatcc
    20401 aatttcctag ataccaaagc cctacaacta ggttctggac atcttatttt tagactctca
    20461 tctgctactt taaatccaca tcgtgggcat atactacctg gacgtgatga tacttccttt
    20521 ccacatttag gacactttgt caactttatc ccctccagta aactcaattt aattgatagt
    20581 tgaaatttct ctctacaata atatatgcaa tataattaaa tacgtttcac ttacaactat
    20641 ataagttaaa tttttataat aaaaatcccc tatattcaat ttacaaatac ttaatttgat
    20701 acattgaaca ataggggatt ttatttttat ttagttacat attttgcagt ctattattat
    20761 ctaggatttt ttatagatgc ttgagctgct gcaagtctag caattggcac tctaaatggt
    20821 gaacaagata catagttaag tcctacacta taacagaact ctactgaaga tggttctcct
    20881 ccatgctctc cacatattcc tagttttaat tctggtttaa cttctctacc taatttagct
    20941 cccatcttaa ctaacttacc aacaccattt tggtctagta cttggaatgg gtctttttct
    21001 aatatttctt catctacata ttgacctaag aatttaccag catcatctct tgaatatcca
    21061 aatgccattt gagttaagtc attagtacca aaactgaaga agtctgcttc ttgtgctatt
    21121 tcatcagcag ttaaacaagc tctaggtatt tctatcatag tacctacagt ataaggaact
    21181 tctatacctt cttcttttat tatagcgtca acagtttcta ctatcatttt tcttattatt
    21241 tttaactcat ttacttctcc aactaatgga accattatct ctggagaaac tttaacacct
    21301 gctttgattg cttctatagc accttgtatt atagctttag attgcattac acatatttca
    21361 ggataagtta ttgcaagtct acaacctctg tgtccaagca ttgggttaaa ctcatctaaa
    21421 tcaactattc tcttcttaat atcacttact tttattccca tagattttga aagttcttct
    21481 atagtctcat catcatgagg caaaaattca tgtagtggtg ggtctagtaa tcttatatta
    21541 actggttttc catccataac tttaaataac tctacaaaat cttctctttg cattggtaat
    21601 attttttcaa gagctttttc tctttgttct actgtattag ataatatcat ttctctaact
    21661 gctggcaatc tagcttcatc aaagaacata tgctcagttc tacatagacc tataccttct
    21721 gcaccaaact ctatagctgc acgagcatct ctaggattat ctgcattagt tctaaccatc
    21781 atacatttgt gtttgtctac ccagttcatt aatttttcaa aatttccagt taaagatact
    21841 tctgttttct taacatctcc taggtataca tttcctgtag aaccatctat agaaatgtat
    21901 tctccttctt ttataactac atcatcaagt gctcttattt ctttattaaa ctcatcaact
    21961 tttatttctc cacatccagc aacacaacat ttacccatac ctctagcaac aactgctgca
    22021 tgtgatgtca ttccacctct agctgtaagg attccttctg ctttaaccat tccttctata
    22081 tcttctggag atgtctctag tctaactaaa actacttttt ctcctttttc atttgctttt
    22141 actacatcat cagcattgaa ataaacttta ccacttgctg cacctggtga tgctggtaaa
    22201 ccttttgcta taaccttagc ttcttttaat gccttatctt caaattttgg atgtaataat
    22261 tggtctaatt gattaggctc aattctcatg atagcttctt tttcatcaat tattccagct
    22321 tcaactaaat caaccgctac atttattgct gctgctgctg ttctcttacc atttctagtt
    22381 tgtagtatat ataatctttc attttctata gtaaactcta tatcttgcat atctttataa
    22441 tgaccttcaa gtatatgagt aatttttaca aattcatcga atacagctgg cattacatct
    22501 gcaagagttg atatattttg aggagttctt atacctgcaa caacgtcttc accttgtgca
    22561 ttcattaaaa attcaccaaa taatttattt tctcctgtag ctggatttct agtaaatgca
    22621 acacctgtac cactagtttc tcccatatta ccaaatacca ttgattgaat atttactgct
    22681 gttcctaagt tatgagctat atcattcaat ttacggtata cgattgcacg aggattattc
    22741 catgatctaa atacagcctc tattgcaagc attaattgct cttttgggtc ttgtgggaaa
    22801 tcatttttta tttctttttt ataaattgct ttaaattctt ttactatttc ttttaaatca
    22861 tcagttgtaa gttctgtatc aactgtgtat ccctttgctt cttttactct gtctaataca
    22921 ttttcaaatt tatattttgg aacttccata gcaacatcag aaaacatttg tatgaatctt
    22981 ctgtaactat catatgcaaa tctttcattt tgtgtagcct ctgctaagcc aacaacacta
    23041 ttgtcattaa gacctaggtt aagaattgta tccatcattc ctggcataga gaatactgca
    23101 ccagaacgaa ctgatactaa taatggattc ttattgcatc ctaatgtttt atttaagtct
    23161 ttttctaaag tagctaaatg ctcttctatt tcttttatta tctctgctct tatactttca
    23221 ttgttaacat aataatcatt acatgcttct gttgttatag tgaatccagg agggacaggt
    23281 aagcctatct tagtcatttc tgctaaattg gcacctttac ctcctagtaa agatttcatg
    23341 tctttgcttc cttcaccaaa actataaaca tacttagttt ccattgttaa atcccccatt
    23401 aatcttttta ttttaattta tatcattttt attaatagac attattaaat ttctatttct
    23461 ttgtatatct ttagaccatt ttctttcatt atgtctaaaa ttatacctgc tgtttcttct
    23521 attgccttat ttgaaacgtt tattactggg catccaattc ttttcattat ctcttctgaa
    23581 taatctaact cctgaagtat tctttctaaa ttagcatagt ttgctttact ggacaatcct
    23641 aaagctttta atctttgggt tcttatctca ttcagctttt caggtgaatt agtaagacct
    23701 attatctttt tagtatctat ctcaaacact tctttaggaa ttggtatttc tggaactaat
    23761 ggaacattag ctacttttat atttttatta gctaaataca tactcaaagg agttttagat
    23821 gttcttgata ttcccactaa aattatgtct gcttgaagaa cacctctagg gtcttttcca
    23881 tcatcatatt tcactgcaaa ttctatagct tcaactctct taaagtaaga ttcatctaat
    23941 tttctaatta taccagcttc tcttttaggt tttcttcctg ttctcttgct tatttctctt
    24001 agtatatctg tcattaaatc tatacaacta agaccttctc tttcgcaata tctttcaaca
    24061 atactgcata attcttcatc aactaatgta tatacaatta aagcgttttc agcttttgca
    24121 ttctccaaag tttcaagtag tactccttta ttaatcatgt atggaaatct ttttatttca
    24181 taagtttcat tcacataaaa ctgagacata catgcctttg caacttgttg tgcagtctcc
    24241 cctactgaat ctgatactgc atatataatt aggtttttca ccagcatacc tccttaattg
    24301 tcaactattt ctaagaatag cttagttatg ttggtttttg atattctccc aacaactctc
    24361 atatgatttt tgtcttctcc cttatattca acaatcggaa tcgaatctac ttcatgttct
    24421 attatttttc ttgaagctaa taaaacactt gctcctttag ttaaagtgac tacatttgga
    24481 gttcttgtca ttatcatacc tattggcatt ttatttatat cagaacctcc tatagttgct
    24541 tttagcaagt cttttctgga aacaactcca cataactctt cattctcatc tataataact
    24601 atactcccta catcagataa aaacatagtg actattacat catatatact ttcatccttc
    24661 ttagctagta caggcatgct cattatatcc tctactgttt tttcttttac acttttacca
    24721 attaaattta tttcactaac tcctgaataa aaatatccaa cttttggtct tgcgtctaat
    24781 attcctgtca ttgttaatat agctaaatca gatctaagtg tagcacgagt cacattcaag
    24841 ctggaggcaa tactttcact cgttattggt tcattttcct taactatatc tataattttt
    24901 agttgtcttt cattaagctg aataataatc accttctttc attgtgctat actttttatc
    24961 ttttcgcatc ttatatagta tattatataa ctatatatac cattctgtaa acagattttt
    25021 tattgaatac gatatatttt ttactaagtt ctctcgctta aagatattta ttatatatta
    25081 atgggggata tttctttaat taatagaact atattagtat tacagttaat attataatac
    25141 ataattggtc attttaattc attttatatt aaaattttta ataatattat ttcaatgtga
    25201 atataaaatt gcagaactaa ttcaaaataa tttttacgac tacaaataac ctataatata
    25261 cttttaaaga aagtatccta acaagaatat ataaaaattt aaaagggttg atttaaaaat
    25321 aaccatcaac cctttttact aatatctatt tatattacca tcaaatctta cccaaatatt
    25381 ttttcttgca attgtcttaa atgatataaa gtagtatctt tttctatctc taccatatcg
    25441 taagttataa cttcaccttt tttaatatct tttacaactt tagtcttttt acttatcaaa
    25501 ccaataggta cagcattcat agcctttgct acatcgtatt tttctatagt accatagcat
    25561 gtatatgctc catagccatc cataaactca ccttttttca aatctttctt agctatagtc
    25621 ataacttctg ctactagtcc agctttaggt actattgtag ccttatggtc taaaactgcc
    25681 atagctgctg ataaaggagt ctctaaacta cataaatgat atggtctata taatatgtaa
    25741 ttaggtccat cacccatact taaatatttt agttcatcat taactgcttt taatttatgg
    25801 gcaactacta cgaaaactcc aggtgctata ccatttacaa aatcaactac accataatta
    25861 tctaatactc caccttcgct ttttaatgca tatttcttag gtacttcatt aactgtagct
    25921 tcaataccat gaccacctct tacatcaggc acaaatccag ttgcattaca cattaaagcc
    25981 atttctacca ttgttttagt tccttcttta aaagaagcta tcatatgagg tgaagctcct
    26041 tttctttctg cttcttctct aactgtatca ggattacaat ctaaatctaa tttattattt
    26101 ttacctttac ctatcactct aacttcaaac cccattgcat ctgcaaaatc aaataattcc
    26161 attactgcac ctggctcatc tcctgcagaa cctgtaaata ttactccagc atcatctgct
    26221 aattttttaa gtattggtcc aacaacacaa tcagtttcag catttaacat aactatatgt
    26281 tttttattta aaatagagtt taatgctatc tctgcaccaa ttgcaatacc cccagttgca
    26341 tctataacta catctattga cttagtttta caagccacaa gaaagtcatt acatgtcaat
    26401 acttttcctt cttgtaattt tatttctgca tccttttcat ttgttacatt atctataatt
    26461 tcttcatcta ttcctgcatc agtaaaagct ttatgagcca actccaaatc tatatctaca
    26521 acaatagaag cttcaatacc tttcatattt gccatttggc ttaccattcc atttcccata
    26581 tgcccagctc ctataagagc tacttttatt tttttacctt cctcttccaa ttttgcaagt
    26641 tttctgttta aatctaacat accaattcct cctgttataa taattttatt ttcaaattaa
    26701 gaaatagtta ttaaatctcc aatagttata tctggatttc ctatttccac atgtatttct
    26761 cctggtaaat ttacttcaca ttttccatca aatttgattg tacaatgccc aatttctcta
    26821 agagtcttct gagcaatatc accaactgaa actatacaat aatctctatt ccctatagta
    26881 agtgtatctc ctatttcaac atcacttttt aatgttgcta ttgaatgaat tacagatata
    26941 tcctttaagt cgtcatcatt aatggtttca tcatatataa taagacaatt gctttcatcc
    27001 attaactctt taactaaact gcctatccca cttatcttaa cttcatattt catgacattc
    27061 ctcctgataa tttatattta tattgagtta attaaaagaa acatttattt tttcttttat
    27121 aaattttata gcttgtacaa tactctcttc atctttaaat ttttgctctg cactatatat
    27181 atctaatcct tctatttctt caatctcttt aaatttagcc attactgtac gcccttttaa
    27241 aatttctcca aactttataa acccatctga atctgaagat ataacggcta tacttccttt
    27301 agaaaaatag cttttctttt tgcctgtaga cactatatca cccttttttt tagctctatt
    27361 taaagtttta aaatacaatt tattctgctt cattataaat atagtattta aaatataagc
    27421 aacaaataaa attactaata atttcatatt tatacacctt ccaaaaatca cattattttt
    27481 aaatctgtat aacaactata aatgctgtac aatagttata taaggttttt aagtaacacc
    27541 tttttaaatt ctaaaaaagt tctacattta cttatcttat tcgttaattt tacatcttgg
    27601 cctatcttta aaacttcttc ataaattttt actaataagt ctgagtctat cttattctca
    27661 catggaaaca ttgtcataag aattattttt atacttctat ttgcatattc tattggttct
    27721 tctaaaattc caactgccat taaaaactta tctgattttt catttataga atgaggaaat
    27781 aataaacctt tatcaaatac tgtgggagat ttttcttctc tattgactat attttttcta
    27841 aacttctcat caatacatcc caaatccata agatggtcca tcattttttc taatgaggca
    27901 agtatagtct tttcatttaa tatcataaat ttatcttcat ctaacaaatt atttattagt
    27961 aaatttgtag aattagtagt gtcaatattc ccttctctta ggcacaatac tgtttttaat
    28021 tgttctctta gtttgttttc atcaaatatt gtatttattt ttaatactat tgtatttata
    28081 tttgatgtgt ctaaatcaat agttgtaaaa actatatcgt attcatctaa gttaatattt
    28141 ctcaaattaa aacttgaaag agtatcaatt ttaggattat ttcctatcag tttttctact
    28201 cttattttca atagttttgc tgttcctaga cctgtactac atataattgc tatttttttt
    28261 attgaataga atctactgct atttctttct aaatatccac tgaaatggat tgctatatat
    28321 ccaatctcat cttctgaaac ttctaagtta tactttttct ctattacttt tcctgctatt
    28381 tgtgctaatt taaatggaag tatataattt tgcttaatct cttctaacaa aacatttttt
    28441 aactttatat taaataatag cctgtttaaa gtaaaactaa gatgatatcc tagacctact
    28501 cttaattcat cctcatttat aaaaataccc atatcgacat atatttgatt aaatatattt
    28561 tccatcaact catcaatgtt tttactaatt ctactactat ttaaagcaca ttctgatgct
    28621 ggtgcatttc cactaactaa cggtatagtt aaataaataa tttcttcatc atttaaagta
    28681 cattcaaaca ttcctgatat tatatgtttt atttccctag caataaagta ttcatcatat
    28741 gatttaagta aatcaaactt tacatcataa tcttttactt tcttttcttc ttttactcta
    28801 tagactaaaa ctactatgta gttaataact tctcttaaca tttcatctgt aacataaaaa
    28861 ttattttttt taaataaagt caatagtttt tcttctaaat ttatgatttc ttcttttttg
    28921 attcctttaa aatactttga attactgaaa tctttccttg agtttttata caactgattt
    28981 aatataaaca gtctaatatc aagttcattt ccatttaatt tcatacctgt attctgtttt
    29041 ttaatcaagt ttaaattata tgaagccaaa actttttcta catactggaa atcatttact
    29101 aaagtagttc ttcctacaca catctcatca gctaaactat caagtgtaat aaatccatct
    29161 agttctatca agtaatttag tataaactct actctatctt cttttgaatt taatgaaaat
    29221 acattttttc tattcatatc aataatctta ttgagtatct gctcatcttt tatttctagt
    29281 ttatagcctt gaccctttat atatttgatt actgctatat cattacctaa atctttattc
    29341 aattgtttta tatacgtcct tacacttcta gttgtgacat tcaattcatt tgctattgag
    29401 ttaatactca caaactcttt tttactacac ataatcaata tcttaaatat cttgcggtca
    29461 atagaaggaa ttttctcagt tacactcatt ttgtatctcc tccttgattt cattctagta
    29521 caaatttgaa accaaattaa tacataaaat ttcactttaa taaaggaaaa tttagtatta
    29581 atctaactcg ataattacag ctaattaata gtataaaagc tagtctttca ttaacaaaaa
    29641 atcttgacta gcttaaattt atatttacaa ttttattaat taattccaag ccttatattg
    29701 acattaaata ttatctcaat gcaaatactg caactccata tgcaataata acagctattg
    29761 gaccagttat taaacgagag taaaataaag ctggaacacc atactctaca gtttctggtt
    29821 ctgcttctcc caaacttaat cctactggta caaaatcaca tccagcttgc ccatttattg
    29881 caaataaagc tggaagtgct aaatatgctg gtattgcacc aagaccaatt tgtgtaccta
    29941 caagagtccc tactacttga gctataactg caccaggtcc tagtattggt gataagaatg
    30001 gaagtgtgca aattactgat ataatcaata atccaccaat attacctgca agtggagata
    30061 taactcttgc aatccagtct cccagtccag atgctaaaat aattcccata agcatactta
    30121 caaatgccat aaatggtatt acgttattca ttaccatttg gatagtatct cgacctgcat
    30181 cataaaattt tgatactact tgccctgccc cttgaccaat agaaagtatt atgttctttt
    30241 tagcatattc accttgtgct tttgacttaa cctcatcata attatcaggc tttctaatag
    30301 aactcttatt ttcgctttta ttttcttgag atttttgtgg catatcttcc ccatctacaa
    30361 cacttataca gttaggatta acatctgata cataatattc ttctgttata aattttgcta
    30421 aaggacctgt ttttccaact ggatttacat ttattgtagg tatttttttc tttggataaa
    30481 ctccacatct agcagttcca ccacaatcaa taataactac tgctacttct tcatcagaaa
    30541 ctccagtttt aaatccatct acaatttcac aacccagtag ttcttttatt tttaatgtta
    30601 cttcatggat accgccagca gtcattgata gtatcttatt tctattccct tcttttttta
    30661 tatacaaagg acctccccag cctgaagttc ccttttctat ttttaatatt ttattctcct
    30721 ccattttatc tacctcctaa gccttatttg ttgctctatt ttttcttgtt agaaaagcat
    30781 acattttttc tgttactata cctcttataa aaattacaat tagaccaact ataaaatacc
    30841 acaatgccaa tgtagtagtt tctttaccta aagtagtcaa acctgcagat attcccaacc
    30901 atacaaaaag ttctcctgca tttgcatgtg gaaaaagacc tgtaattgga tgtacaaatg
    30961 aaactgctgc atcataaaat cctgctttgt gctcttcttt taaaaatcta ccaaatgtat
    31021 agcacatagg atttcccaag aaaaatactg atactaatgg aagtagaata tatcttgtaa
    31081 aagagttctt tcctagctta gaagcccaat tattaactct ttcctcacca attatcttaa
    31141 tcaaagagtt aatagctacc attaatacaa ttagcgttgg aagagtacct gaaacaagac
    31201 ctataaattg ttctccccct ttctgaaaca aaccgataaa ccactctgca cctttactta
    31261 gacctgtaat aacgttttcc ataaaattat aacctcccta taatatcttt aaatttttaa
    31321 ttttactgct taccataaat tttacaaatt acatcttttt tctgtactat atgctaatat
    31381 tgtaaatgtt tttttattaa tatcatttta atataatatt tttgataaat aaatacatct
//
LOCUS       DAYAOO010000042        30890 bp    DNA     linear   BCT 12-OCT-2024
DEFINITION  TPA_asm: Clostridioides difficile isolate ST8-SSI-h139-18
            SAMN40601845-rid21577343.denovo.042, whole genome shotgun sequence.
ACCESSION   DAYAOO010000042 DAYAOO010000000
VERSION     DAYAOO010000042.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN40601845
            Sequence Read Archive: SRR28438827
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 30890)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 30890)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-MAY-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-MAY-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002157583.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002157583.1
            Genome Coverage       :: 163x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/11/2024 16:19:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 4,038
            CDSs (total)                      :: 3,963
            Genes (coding)                    :: 3,930
            CDSs (with protein)               :: 3,930
            Genes (RNA)                       :: 75
            rRNAs                             :: 6, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 60
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 33
            CDSs (without protein)            :: 33
            Pseudo Genes (ambiguous residues) :: 0 of 33
            Pseudo Genes (frameshifted)       :: 7 of 33
            Pseudo Genes (incomplete)         :: 25 of 33
            Pseudo Genes (internal stop)      :: 11 of 33
            Pseudo Genes (multiple problems)  :: 8 of 33
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..30890
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN40601845-rid21577343.denovo.042"
                     /isolate="ST8-SSI-h139-18"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Denmark"
                     /collection_date="2018"
                     /collected_by="Statens Serum Institute"
     gene            complement(80..616)
                     /locus_tag="ACGI5H_002174"
     CDS             complement(80..616)
                     /locus_tag="ACGI5H_002174"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418051.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0008757 - S-adenosylmethionine-dependent
                     methyltransferase activity [Evidence IEA];
                     GO_process: GO:0007059 - chromosome segregation [Evidence
                     IEA];
                     GO_process: GO:0008152 - metabolic process [Evidence IEA];
                     GO_process: GO:0032259 - methylation [Evidence IEA];
                     GO_process: GO:0043170 - macromolecule metabolic process
                     [Evidence IEA];
                     GO_process: GO:0043412 - macromolecule modification
                     [Evidence IEA];
                     GO_process: GO:0044238 - primary metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="IbrB-like domain-containing protein"
                     /protein_id="HFG9697877.1"
                     /translation="MEYKSPVYGIIAVPIEKIESNDYNPNAVAPPEMQLLYKSIKEDG
                     YTMPIVCYYNEEKDKYIIVDGFHRYRVMLENEDIYDRENGLLPVSVIDKSLDERMAST
                     IRHNRARGSHNVDLMSKIITELCEIGKSDEWISKHLGMEVDEILRLKQITGLAYLFKD
                     KEFGNAWIPFGSDIEEEN"
     gene            complement(634..1947)
                     /locus_tag="ACGI5H_002175"
     CDS             complement(634..1947)
                     /locus_tag="ACGI5H_002175"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438907.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3440 domain-containing protein"
                     /protein_id="HFG9697878.1"
                     /translation="MDKRYLESDVFEAFQERLSYLFNEFDYIYVSFSGGKDSGLLLNL
                     VLDYKRKNNISSKIGVFHQDFEAQYSLTTEYVEKVFEDNIEDIEPYWVCLPMATRTAV
                     GNYEMYWYPWDDEKEELWVREMPVKEYIINQKNNPFTYYKYKMRQESLAKQFGRWIRD
                     IHEGAKVVCLLGTRAAESLQRYCSIVNKQHGYKGKCWITKEFKNVWTASPIYDWEIED
                     IWLAHYKFDYDYNKIYDLFYKAGVAPRKMRVASPFNDSAKESLNLYRILDPDVWVKLV
                     ARVQGVNFTSIYGKTKAMGYRSVKLPYGHTWKSFTYFLLDTLPENIRNSYIKKFSTSI
                     EFWQNTGGGLSEIVIRELLRKGYKIELNGVSNHTKDKKSRVIFLDDIPDDTDDIKFTK
                     DIPSWKRMCYCILKNDHMCRFMGFGPTKEQRIRTEYIKKKYEKIH"
     gene            2302..2742
                     /locus_tag="ACGI5H_002176"
     CDS             2302..2742
                     /locus_tag="ACGI5H_002176"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888386.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3788 domain-containing protein"
                     /protein_id="HFG9697879.1"
                     /translation="MYERMLDKSNKPCLSQIIEYIGKDGYARLCKLETYLKTQYNLSR
                     ELRFPFGNNYGWGYKYSHKSFHLFYAFFEKGAFTVLIQIGDKQVPAVEKTLVALTPKA
                     KELWVTRYPCGNNGGWIKYRILEDADLLDIIQYIRAKKSPPKQN"
     gene            complement(2926..3114)
                     /locus_tag="ACGI5H_002177"
     CDS             complement(2926..3114)
                     /locus_tag="ACGI5H_002177"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438914.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipoprotein"
                     /protein_id="HFG9697880.1"
                     /translation="MNKNNNLVIICMFIGMILGMAIGCAIGISKGNVGITMCYGLIFG
                     MIIGICIGTIIKNSNKKE"
     gene            4136..4531
                     /locus_tag="ACGI5H_002178"
     CDS             4136..4531
                     /locus_tag="ACGI5H_002178"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429546.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF6110 family protein"
                     /protein_id="HFG9697881.1"
                     /translation="MNILKMKKTGIFLGGVLFGTVGVKILSSDCVKKTCTRATAGALK
                     VKDSVLETTTKIQENVEDILAEAKEINEQEDLSTSKVNVVQDTLKCEQEVLKTETIKT
                     VEDTNSNSIKCEEIKDNVIEEKNSTCTTE"
     gene            4574..6673
                     /locus_tag="ACGI5H_002179"
     CDS             4574..6673
                     /locus_tag="ACGI5H_002179"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729454.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0042625 - ATPase-coupled ion transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0006812 - monoatomic cation transport
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="heavy metal translocating P-type ATPase"
                     /protein_id="HFG9697882.1"
                     /translation="MNFYIKHEIRGRIRFDLQLGKLNNKQSDTLLYYLTSINGITKAK
                     VYDRTGDAVIYYTGEREYIIREITKFSFNNSKIENLVPEHTSRELNNYYRDKLANKLL
                     VKSISKIFFPKSLRFFLIGLHSIKYFKKGLSSLLNKKIEVSVLDATAIGISIFRKDIN
                     TAGSVMFLLGIGELLEEWTRKKSIDDLAQSMSLNIEKVWLRKGDTEILIPISEIKEGD
                     LVSVTMGNMIPLDGVIVSGETMVNQASLTGESLAVNKKEGSYIYAGTVIEQGNIVMCV
                     KEKAGTTRFQKIVTMIEESEKLKSSVESKFEHLADTLVPYSFLGSILTYAITRNPIKS
                     LSILMVDFSCALKLSIPISVLSAMRECNNNNITVKGGKFLEGVACADTIVFDKTGTLT
                     KAQPTVSDIITFQNYNKEDMLRLAACLEEHFPHSIANAVVYEAEKQGLSHKEMHTEVE
                     YIIAHGISTKVDDKKVVIGSKHFVFEDEKCTIPDGEEDKYNNLSDEYSHLFMAISGKL
                     SAVICINDPLRKEAKYVISNLRECGIKKIVMMTGDSEKTAKSIASKVGVDEYYSEVLP
                     EDKANFVKSEKLKGRKVIMIGDGINDSPAISESDVGIAMSEGAEIAREISDITISADN
                     LNNLIVLKQISNKLMKRVDLSSKFIIGFNLGLILLGVGGFVRPSTSAFLHNTSTVGIS
                     LNSMTNLLENTNTYNYH"
     gene            complement(6898..12108)
                     /locus_tag="ACGI5H_002180"
     CDS             complement(6898..12108)
                     /locus_tag="ACGI5H_002180"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438922.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTPase"
                     /protein_id="HFG9697883.1"
                     /translation="MANKLYSEIVNLLEEGRDELRKYDLKEKSILLFLGASGVGKSTC
                     INYLKGCVMEEKTDEETGQIYITAKDSAVEIGNGVYSKTLCPEVVDIANRDFSLCDCP
                     GFFDNRGAEYMIAGAMLVRETISTSSKVKGMVVILDYQSLLDSRHTLLIETGKNLKDM
                     LGDYAKYKENFFFLINKIPKTLIGNVTEEKIRNILEKAKEDLDSQEKDYDGCKELVYL
                     LNVALSDGVSIKLCNPLDKQPEKLLDEMKNLPETFEKTDLGLMLTASCKIEIQKAVDV
                     TYKDLEKLLVPYIESVKKGMEDSISILSSINSLKDKKIQLDKMYTDLCSRTNNMKELM
                     EFVQELSYGDGVQKVNILEETRLLLELNSYCSETHIVGLSELLKSLLKNTLEDTLKDI
                     KYWIAEEEYREEEAKKLEDAEYRIEKIQSCTYIKSYEKENVLSIYIPIPKVNLSDLTK
                     IISGYQLNILSSIYMYGDCELKIDCNMEKEVFSGKNIVLLTEKLHIPEGTYSINVSGK
                     DAEKLVGESSIYDGMNGRNGNNAGTSGDIILSFKEIEKRGELKLYVDGGRGGNGQDGK
                     KGDTGITGEAGANAKIGSKKESKEFANVKGTKYYVVKAEKGKQGGTGGTGGNGGNAGL
                     GSKSGQVYLLGKAPLLKSAISKKDGNHGLAGKGGSGGAGGAGGLGGIRGIYEETIRYI
                     GTSPPMDNSDRNYYYFDRYVFNHALNQKQAADDGEKLNTLYEEHKDWTISKREDSGSA
                     GAEGKAGHSGDALKEKELLKQEYSLSIDTFFYEFFERFGFSGIKGYRNLRLLCAVGIL
                     EADILEFSHIYEIFYAVEKIEMQLNREILQKYYSFEKKNKAVLSMDDMNIKKEFYKEA
                     KEIYEYLINKLMQSDRIESFVGKNQNFSEWSMILFALEQKTAFYVQMIEESEIGGNRV
                     TDIRSLTDYLDKTLRELEQGKKDELKEGYFNTYKESILTQIESGNQQIEVLKNELENK
                     MLSVNAKMNLLIQEIIKMKEDEQEDIEELKKKQAKLEEQMKTQLILSGIQSALSLLTA
                     FSGVGQACLGAFDSAKSLKENLSAKEEEYQWTNRMVDFSDFKLDSDGMRFVLGEQLSE
                     DRKNALDKMTYNLAGVDEERRTKFDQIKEIIVKSIDDDNYADKADDIQRAKEGLSESE
                     YKEIYTKIQKKEIGMLEANYNNKQQKDKLAALEKSKQAIERQQKTSKIKNALSIGSSA
                     CSLINTAISGVNNCLNVKSSFESKIEVVKEAIKDKENNIKKLDELNTQMVEFKDKTLK
                     ESVIPFVEKFDSTVKNQDIFENEISKLKMKEVLTELSTKFGSLKMENSEEISIIFKKV
                     QDMMETQIIITDKIDKKKDNLAMGELIYQMSDSGNQMNEYQKKLIHQIELNQVRYLCQ
                     VEAAAFQLWTFPFGSNIVNILNRCHVGITEDENEVINQAKEQNRQIREFLDQDAYQWQ
                     KTDNHILKVALTGSLDGKSRVGFENTYSLYDCNEEEVKKLLTGDEISFEVPLNKNFDA
                     IKYVTMYANIPNLRRNILEDSLKVKVHIHLYDSGYFSLYDDKKDVYYQYVFPQNYINI
                     THGLDIKYNDSDSINSIWSSVEDKGIEKFKNAGLNSGRSPYSMAKISLKAHFNKKLSY
                     DSLTNEQKKKLESYFDKPSKYAWSDSIDILRSLGYIDLKGILSKSWYEIKKDIDSDGE
                     IMKHFSILQVDLLERIIYEQTSILKENIPNLTIELVGCGIYVESEFNYLKQNDLKCYE
                     ERLVENTIIG"
     gene            complement(12123..14618)
                     /locus_tag="ACGI5H_002181"
     CDS             complement(12123..14618)
                     /locus_tag="ACGI5H_002181"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902013.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HFG9697884.1"
                     /translation="MPENNNQLLEEITLLLNEGKVAINKAENQNLILILGGTGCGKST
                     AINYLAGCVMMEVEDEDTGISYIDCLDPVAEIGSGAVSQTLYPNIVNMRKPIEGMDAK
                     LCDTAGFSDNRGVAHDISAAVSLGEVFKNSASICAVIVLIPEADILDSRLTKVLDLFQ
                     QLNMCLHKENFKGSITFFISKSFLGRTEKQIYNVIKRKYEQLCENLDSNIEEKAWLFE
                     ELLKDNGKNIHLCKPLASDEREGLLKQVLELDEVKDKTSAFQYPISADARLVLDTLIK
                     EIQNNIVSSLEDYVKAYTEDFINIIGSITMIQEIAKYDEVVKVFKNWLESTTSLTIES
                     FINVLAKQSGLFLQDSCMKLQNKIKGNLDIIDALSKYTEHGTGEILLPSVHMEFIIEK
                     ASKKIMEQNFIIIRKNLEKVLVSYEVQKQVFTLPNREKLMEVANKKDYVYSVSDFNSI
                     LTNVTVTQNEELEDSITRLSAYGEEGNEIIREFIGKYILNPFIVKTININDKKGIEIR
                     ALIPNLVISSVLEYFKNRKVDDNVSTFMFFAKDTIYMDDNLGMNFASEKNIILASNNL
                     DVGSNVKINVSGKSGELVDNSMYGKNGEDGRDAGNIYLYIKEEIRNYRLTLIANGGNG
                     SKGIDGENGETGASGSNGADAGYTSYFHGQMFKGYFEKGTSGKKGEKGGAGGNAGRGG
                     NAGKKGNIYFISDSEEQKNRIINHCDITVKDGEAGPNGRPGLGGYGGSGGYHGYNTLS
                     FSPSGIDKTVYYTGYFTSWDYKLDSIIKYHIEFSGGSWNEGKTGPAREYAEYGDRGDN
                     GGFNAPNTKLSTAVSKVEENLIKEKYQGYCSEI"
     gene            complement(15279..15566)
                     /locus_tag="ACGI5H_002182"
     CDS             complement(15279..15566)
                     /locus_tag="ACGI5H_002182"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429630.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9697885.1"
                     /translation="MRLNITKQNTIEVENSRKEDVYFVIVDNVFFERQGDVFNSITNN
                     NLNNYDVKILPTDNIFLELKITSTKDLEPVFIVVEDRQYNHGSIMFKPVLV"
     gene            complement(15586..15861)
                     /locus_tag="ACGI5H_002183"
     CDS             complement(15586..15861)
                     /locus_tag="ACGI5H_002183"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9697886.1"
                     /translation="MSLFVGGWSKFRAVEEEDLKVFNEAVGMLEGVGYEPLIVSTQVV
                     AGTNFKFICNATSVTNPPQNYLAEIVVFKPLPCDEHNATITSINIIK"
     gene            complement(16516..16695)
                     /locus_tag="ACGI5H_002184"
     CDS             complement(16516..16695)
                     /locus_tag="ACGI5H_002184"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895603.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF6440 family protein"
                     /protein_id="HFG9697887.1"
                     /translation="MGKDRFEKVYSQGKINATEIWVDKETGVNYVFHYYGNAAGFTPL
                     LDREGKPVISPIVSK"
     gene            complement(16980..18455)
                     /locus_tag="ACGI5H_002185"
     CDS             complement(16980..18455)
                     /locus_tag="ACGI5H_002185"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729457.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HFG9697888.1"
                     /translation="MKRKPQYLIIFEHIIQQIYTGKITIGDRLDSIKSMSEEYMVSKN
                     TIKTVIKMLSEKGFIETKAGSRPVLIQSTSKQSIESDLLYEKILQISEIYKIFSLIFP
                     SIAMYNIKRFTSKDFEELNEIIDCMEKNSSNYLVFKEQRLKYINKLISKTNNFLIHHF
                     CEIIQHDVIISQLAYNFDNLDNLDNCCIDFFRNKYIEQVRKTYLYGLDGNLIEFKKLL
                     TYMYKACRESILKMVENRAPQSIDTSSFNSVTLEKCYLYDLIVSDVICQIFEGNIKIG
                     DCLPSITSIINRYNVSLPTVRSAYNELNELGIAKTINGKGTYVTLFSEYDDDYINTEE
                     GAKRLSLLLDAMEFVTITLEDVVLLLGNKMDLIAVDKIETHLRYLQNNCEECKVYPDF
                     VLLCKIVDYTQIYVLQETFLHLKQYMIFGIYLERFFHEEYNEILKTRFDVCFEILRYL
                     KKGDVERFAESFSNIFKESLQYLKKVISSLNVDMRLKLGIL"
     gene            19486..20664
                     /locus_tag="ACGI5H_002186"
     CDS             19486..20664
                     /locus_tag="ACGI5H_002186"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902010.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GGDEF domain-containing protein"
                     /protein_id="HFG9697889.1"
                     /translation="MKYHIFLIITTILIIELCNIYICKIASFGNKNITIHKNYKYIFL
                     IKPLTFLIIIFTKLPLPLYYILFYIVSHKLLLSRKSSTNNHFIPNMAVISFCILHLIT
                     VSTISLVKNTSPDIIFANMTYKLISILIASILDFILWYSMNKIKEHIYIITQNQIEFS
                     LFLKFIWFTLGYILFDSIQITFAPPSSLTSYFILGSNILLILQLIIFINHIYSIEKNI
                     YLEKEHNRLKMIKQEQLLKVNLLKKKANIDELTSAYNRKFAFEKIQHYIDNNLLFSLI
                     YIDLDKLKTINDTYGHLAGDNYIINFSSIVIENLGIDDIFARIGGDEFIVIMPKSNEN
                     TTKEFIEKISKIMDNTISFSYGIVEVSSENKMTVEEIINIADIRMYTNKQNNHKRNNN
                     "
     gene            21014..21895
                     /locus_tag="ACGI5H_002187"
     CDS             21014..21895
                     /locus_tag="ACGI5H_002187"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003432854.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GGDEF domain-containing protein"
                     /protein_id="HFG9697890.1"
                     /translation="MPAYLFDSNSIANIYRVFPISFSFIVTGLYFSYKNNKNNKINFE
                     AVLEDKKNLIFLLSLMFGMYLYLCLSLSIYYTVGNVLILKLYGIKSAIIVLVGNYIAE
                     RYSFRITQIKGYDIKNQIEYVESVKTEYEINKLNDIVYTDLLTGFYNRPFVNQKLSEW
                     TSNHYKFTLCFTDLNSLKPVNDKFGHQFGDKYISTTAQIIKKLINVENSLLFRYGGDE
                     FLFLLQNTSCVEAEKIMININYELSKLSNTDEYPYALSISYGLVEWDGISDIETLISK
                     ADSLMYENKLKNKSTLN"
     gene            22104..22253
                     /locus_tag="ACGI5H_002188"
     CDS             22104..22253
                     /locus_tag="ACGI5H_002188"
                     /inference="COORDINATES: protein motif:HMM:NF012772.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EAL domain-containing protein"
                     /protein_id="HFG9697891.1"
                     /translation="MTTVAEGIETSFQKDFLQEINCDMLQGYVFSRPLPIKDFEKLMF
                     QNSSN"
     gene            complement(22513..25080)
                     /locus_tag="ACGI5H_002189"
     CDS             complement(22513..25080)
                     /locus_tag="ACGI5H_002189"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002602373.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016301 - kinase activity [Evidence IEA];
                     GO_process: GO:0016310 - phosphorylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PEP/pyruvate-binding domain-containing protein"
                     /protein_id="HFG9697892.1"
                     /translation="MIYYVLPLEHKQATIEIVGGKGMSLSKLLTAGIPVPDGFHVTTA
                     SYQIFVETNHIQSRINKLLDGIDSNNTSQLEDVSKKIGELFHNGEMPQEVSDAIKMAY
                     AGLGNISVAVRSSATAEDLPDASFAGQQETYLNIQGEDKVIDSVKRCWASLWTARAIA
                     YRVKNNIKHEIVALAVVVQKLAFSDSSGIMFTLNPINGRRSEMIINAAWGLGEAVVSS
                     LVTPDTIVVDKDSERIISYEVANKEIMTVRTSEGTEETMVPERLRKKYALTRNQVMQL
                     IQLGKKIEKYYQMPMDVEWALEKDKLYIVQARPITVLPPEWVLPEQDVVYTKGSLAEH
                     LPNPVTPLFATLGLEIVNRASELLWIDMFGKSAKKLLPKNGAYTVINGYVYLSAKSKP
                     LLIAIKSLSPRSLRRTLMNSVARWETARKGYEDAIKQWEEKPLHTMNAHQIMEGIQTI
                     FYAACIYFTRIQLTLPAASISETLFTKLFQGAVRRAGITDTSVFLLGFDTIVLQSEKE
                     LWGISEWVKQNNSINLYLQNSPAIKIAEDFMSSVVPVGVSQEVWIEWKNRINKYFKEF
                     GRTAYEFDFAHSTPQETLTPTFESVKTFVEGKGESPFLRQTTFEKRRKHAEEEILQHI
                     GGLRKKLFFKLLHWAQETSPMRENAIYLMGMGHPLIRCMFQEISERFIRGGAISHLDD
                     IYWLTKSELEVLIEQLDKNKSLSDMNGIIPVRKAELKKYMGYMSPSKLPEKNKKTISQ
                     AQQKQKDGKIVLTGIGTSTGVVTAPACVLNSPADFESFQPGSVLVAVTTTPAWTPLFS
                     SASAIVTDIGGPLSHSSIVAREYGIPAVMATHIATRTIKSGQMITVDGLAGTVTFDE"
     gene            complement(25083..25688)
                     /locus_tag="ACGI5H_002190"
     CDS             complement(25083..25688)
                     /locus_tag="ACGI5H_002190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860862.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HFG9697893.1"
                     /translation="MPKGIVLTPEQQAERREKIVAVALSLMAENGFQKTSMREIAVLA
                     NMGKSSLYDFFKTKDEIVVYAVEKEIEKTIQQVHRIIDGEPSPQQCLRKIMLNHLRFP
                     EQYRTVLMWLNTESDYLEEEYRKRLKDARYAYQDIIKSVIDNGVTTGIFRKTDTALVT
                     RLLINSMLSISYTSRPLDSSEKMLDETMNIFLNGIMNDGGE"
     gene            complement(26062..27522)
                     /locus_tag="ACGI5H_002191"
     CDS             complement(26062..27522)
                     /locus_tag="ACGI5H_002191"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895591.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADP-dependent glyceraldehyde-3-phosphate
                     dehydrogenase"
                     /protein_id="HFG9697894.1"
                     /translation="MFNELKTKENVYKNLINGKWVESNSRKPIEIYSPIDNSLVGKVQ
                     SMTKHEVDEVIKNTKESIKVWAEMPVYKRGNIFHKAADLLLENIDEIANILVLEIAKD
                     IKSARAEVERTADFLRYTADVGKNMEGEAISGDNFPGGTRNKMSYVSRVPLGTVLAIS
                     PFNYPVNLSMSKIAPALIGGNAVVLKPATQGAISALHVVEIMRKAGIPDGVLNTITGR
                     GSEIGDYVVTHKGINFINFTGSTEVGQHISKISGMVPLLLELGGKDAAIVLEDADLDF
                     AAKNIVSGAYSYSGQRCTAVKRILVQESVADKLVGKIKPLVEKLTIGNPMDEVVITPL
                     IDNKATDFVQGLVDDALHKGAKLITGNVRKNNLFYPTLLDNVNVDMKIAWEEPFGPVL
                     PIIRVKDINQAIEIANQSEYGLQSSVFTSDIDKAFYIADKLEVGTVQINNKTERGPDH
                     FPFLGVKASGMGTQGVKYSIEAMTRPKAVVVNVREL"
     gene            27868..28446
                     /locus_tag="ACGI5H_002192"
     CDS             27868..28446
                     /locus_tag="ACGI5H_002192"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902006.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HFG9697895.1"
                     /translation="MAKSFTEIEKDNIRKRLISECEINWSKYGYKKTNIDELCSKSGI
                     AKGSFYTFFDSKEKLFFEVLNGIQNRLISSVDEILSNMPPKEGFAKSLKMLYRLYDKN
                     PFLYSPNNPDFISLINKLPQDMFLQLESNNIQSFYDLIERHNLKLKIEKEKVFGVCNA
                     LLSSLLVKENIEYNYIEVFDFMVDNLVEHILE"
     gene            28737..29987
                     /locus_tag="ACGI5H_002193"
     CDS             28737..29987
                     /locus_tag="ACGI5H_002193"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888369.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HFG9697896.1"
                     /translation="MVKSSNTFNKNFNLMILGQIISLFGASILKFALSLYILDITGKA
                     EIFATILAVSSIPIIVFSPIGGAIADIFNRRNLMVIFDFSSSLTVLILAVFLFNNNGS
                     ILLVGIIMTILSVISTMYQPTVQSSTPLLVDNEHLMNANGIVAGVASLTNIAGPVLGG
                     VLYGVIGINAIIVISCVSFFLSAIMEIFIQIPFIKQEQNSNIIKTIFTDIKDGIVHIC
                     KENRFILKILFLAIAINLFLSSMLIVGIPYIVKITMGASNFLYGLAEGAISFSSLVAA
                     VSIGIFSKHLKITNLHISFIICAVMFIPMAVSVYPFILNTGFPVPFLIFIVSSMLIFF
                     TTTLISIYVITVTQLKTPNELLGKVMSILFAGTAIAMPLGQVMYGKLFDLLSDRVYII
                     ILGVGFITLLIAFVSKITLRNENL"
     gene            30148..30717
                     /locus_tag="ACGI5H_002194"
     CDS             30148..30717
                     /locus_tag="ACGI5H_002194"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888368.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydrolase"
                     /protein_id="HFG9697897.1"
                     /translation="MSYMPTLEQAWEILRKYNKEEFHIRHAQIVSGVMRYYAKEYDPE
                     RVEFWEIVGLLHDLDFEMYPDEHCVKQRELMTELDLDKSIIDSTISHGYGLTGSDVKP
                     EQFMEKVLFAVDELTGLIGAAAIMRPSKSVSDLELKSVKKKFKDKSFAAGCSRDVIRS
                     GAEMLGWELDKLIQTTIEAMRSLIPEMAI"
BASE COUNT        10434 a         5275 c         3727 g        11454 t
ORIGIN      
        1 taatattaaa actctttatt ttttaatata tattttaaat tttctttttt aataaatctt
       61 tttcttttaa taaatctatt taattttctt cttctatatc agagccaaag ggaatccatg
      121 cattaccaaa ctctttatct ttaaataaat aagctaatcc agttatttgc ttcaatctaa
      181 gaatttcatc aacttccata cccaggtgct ttgatatcca ttcatcagat tttccaattt
      241 cacaaagttc agttataatt ttactcatta aatccacatt atgagaacct cttgcacgat
      301 tgtgtcgaat agtacttgcc attctttcat caagagattt atcaattact gaaacaggaa
      361 gaagtccatt ttctctatca tatatatcct cattttcaag cattactcta tatctatgaa
      421 aaccatctac aataatatac ttatcctttt cctcattata ataacagaca attggcattg
      481 tatacccatc ttcttttata cttttataca acaactgcat ttctggtggg gctactgcat
      541 ttggattata gtcgttagat tctatctttt cgattggcac tgcgatgatt ccatatacag
      601 gacttttata ttccatagca tcttaactcc tatctaatga attttttcat atttcttctt
      661 aatatattcc gttctaattc tctgttcttt tgtaggacca aatcccataa atctacacat
      721 atggtcattt tttaaaatac aataacacat tcttttccaa cttggtatat ctttggtaaa
      781 tttaatatca tccgtatcat caggtatatc atccaaaaat atgactctac tctttttatc
      841 ttttgtatga tttgaaactc catttaattc tattttataa ccttttctca acaattcacg
      901 tataactatt tctgacaaac caccacctgt attctgccaa aactcaatag atgttgaaaa
      961 ttttttaata tagctattcc ttatattttc aggtaaggta tcaagcaaaa aatatgtgaa
     1021 acttttccat gtgtgtccat atggcaattt aacactacga tatcccatag cttttgtttt
     1081 gccataaata gaagtaaaat taactccttg tactctagca accaatttca cccatacatc
     1141 tgggtccaat attctgtata aatttaaact ctcttttgct gaatcattaa aaggtgatgc
     1201 cactctcatt tttcttggag ctactccagc tttatagaat aagtcataaa ttttattata
     1261 gtcatagtca aatttatagt gtgctaacca tatatcttct atttcccaat catatatagg
     1321 agatgccgtc cagacatttt taaattcctt agttatccag cactttcctt tatatccatg
     1381 ctgtttattc acaatagaac aataacgttg tagagattct gctgctcgtg ttcctaataa
     1441 gcaaacaact tttgcacctt catgtatatc tctaatccat ctaccaaatt gttttgccaa
     1501 actttcttgt ctcattttat atttataata agtaaaagga ttattttttt gatttattat
     1561 gtattctttg actggcattt cccttaccca taactcttct ttctcatcat cccatggata
     1621 ccaatacatt tcataatttc ctacagcagt tcttgtagcc attggtaaac acacccaata
     1681 tggttcaata tcttcaatat tatcttcaaa tactttttca acatattcag tagtcaaact
     1741 atattgagcc tcaaaatctt gatgaaatac tcctattttg gaacttatat tattctttct
     1801 cttataatcc aaaactaaat ttagcagtaa accactatct tttcctccgc taaaagatac
     1861 atagatataa tcaaattcat taaaaagata agaaagtctt tcttgaaaag cttcaaatac
     1921 atcggattct aaatatctct tatccatttg aattatcccc tttcaattag aagtttataa
     1981 aaccttacaa tgcaatatta ttatgctttt ttagcagtaa tcagcataaa ttatacatta
     2041 tttaaataca caaatccaac taactacata taattataat gtaattatac ttttgtatta
     2101 taaactatat tttatcatta ttttacattt ttttccaata tatataaata tcatattttt
     2161 ctattagcta aaactaatta ctttatattt ctacgtatta gtataataat acataaaaac
     2221 ttgaataatg cataaaaact tgacatactg ttgtcataat tactttgcta taattaaaag
     2281 taaaaatgga ggtaaattct aatgtatgaa cgtatgcttg ataaaagcaa taaaccctgt
     2341 ttgtcccaaa taatagaata tataggtaaa gatggatatg cacgattgtg taagttggaa
     2401 acttacttga aaactcaata taatttatca agagaacttc gatttccttt tggaaacaat
     2461 tatggttggg gttacaaata tagccataaa tcttttcatt tattttatgc tttttttgaa
     2521 aaaggtgcat ttactgttct gattcagata ggtgacaagc aagttccagc agtagaaaaa
     2581 acgttggtag ctttgacacc aaaagctaaa gaactctggg tcactcgtta tccttgtggc
     2641 aataatggag gctggattaa gtatcgtatt ttagaagatg cagacttact tgatattatt
     2701 caatatataa gagcaaaaaa atctccacct aaacaaaatt aacttttatt ttttgtgatt
     2761 taaatatagt gtatataaat tccattcttt ccatattaaa aaataatata aaaaatatct
     2821 attagtataa cttatttagt atgtcttatt ctacttttta cagataatta aaaagtttta
     2881 tcataaataa atcataacta gacatcctag taaatcaaaa ttaatttatt cttttttatt
     2941 cgaatttttg ataatagtcc ctatacatat gccaattatc attccaaaaa ttagaccata
     3001 acacattgta atacctacat ttcctttaga aatacctata gcacaaccta tagccattcc
     3061 aagtatcatg cctataaaca tacatataat aactaaattg ttgtttttat tcatagtttt
     3121 tctccattca atatatttta aattgcctag ctcgccttct tagcttaaaa caaagaaata
     3181 taaattaact ttctttcatt ctaatatctg cctgtataaa tgtcaaacaa cacatttctt
     3241 gtcataacct cctctttttg aagtaagtac aatctcccag acgcaataat atcaatttcc
     3301 taaaaccatt taagtaactt ttatatttac ataatattta caatcataaa ctatattgtt
     3361 attcatttat acatcataaa cactccctcc taatcattat tatacttaaa ataatgttca
     3421 tttataataa tatatctaac gcactttaat tgaaaaaact aaaactttgc ctttcattcc
     3481 catatataaa taagtatact ttttgatgct ctattacaaa tcaactaaat taattgatat
     3541 aaattatcat tttctgttga aaataccatt cgcacatgct atacttaatt gcataaatgg
     3601 taataaatgt catatgattt tacaaatcta ttaataacaa ttattacttt tactgtattt
     3661 taaagttttt ggactaaata tcaagaactt tctaaaatac aaagtacaaa aaatttatat
     3721 aagttataaa tttatatgaa ctagataagc tcaaacaata tgttatgtat aaactgtgta
     3781 gtattcggtt ataaatttat ataaattata taagctagat aaagtattac ctcaactata
     3841 taagctagat atataaattg cttatataag ctagataaga attatttcaa ctatataaac
     3901 tacatatata aattacatac ataagctaga tatataaact gcatatataa gctatataag
     3961 aattatttca accatataaa ctacacatgt aaaattcata taaatttact aatataaatc
     4021 aaataaaatt actaaactct ctaaactaat tttgtaaaac atactctatt tttaacattt
     4081 gttaccttat acataagtac aaacaaaatc taactaaatg aaaggataat gtaaaatgaa
     4141 tattttaaaa atgaaaaaaa cagggatatt tttaggagga gtactttttg gtactgtagg
     4201 tgttaagata ctttcaagtg attgtgttaa aaaaacttgc actcgtgcaa cagcaggagc
     4261 attgaaagtt aaagattctg ttcttgaaac aactacgaaa attcaagaaa atgtagaaga
     4321 tattttagct gaagcaaaag aaatcaacga gcaagaagac ttatctacat ctaaggtaaa
     4381 cgttgtacaa gatactctta aatgcgaaca agaagttctt aaaactgaaa ctataaaaac
     4441 tgtagaagat actaattcta atagcattaa atgtgaagaa atcaaagata acgtaattga
     4501 agaaaaaaat agtacttgta caacagaata aatttaatga ttattatgat taataatatc
     4561 aggaggaagt aaattgaatt tttatataaa acacgaaata agaggtcgta tacgctttga
     4621 cttacaactt ggcaaattaa acaacaagca gtccgatact ctcttatatt atttaacttc
     4681 tataaatggt attaccaaag caaaagttta cgatagaact ggtgatgcag tcatttatta
     4741 cactggtgaa agagaataca taataagaga aatcactaaa ttcagtttta acaatagcaa
     4801 aatagaaaac ctagttcctg aacataccag cagggaatta aacaattatt atagagacaa
     4861 attagcaaat aaactgctag tcaaaagtat ctccaaaata ttttttccaa agtccttaag
     4921 atttttttta attggacttc attctataaa atattttaaa aaaggtctct cttccctgct
     4981 aaataaaaaa atagaagttt ctgttttaga tgccactgct ataggtattt ctatttttag
     5041 aaaagatatc aatacggctg gttcagttat gtttcttctt ggtatcggtg aactattaga
     5101 agaatggact agaaaaaaat ctatagacga cttggctcaa agtatgtcac taaacattga
     5161 aaaagtatgg ttaagaaaag gtgacactga aatcttaatt ccaatttcag agataaagga
     5221 aggagattta gtaagtgtaa ctatgggaaa tatgattcca ttggatggag ttatagtatc
     5281 aggagaaaca atggtcaatc aggcatcact tacaggtgaa tcccttgccg ttaacaaaaa
     5341 agaaggctct tacatatatg ctggaactgt aatagagcaa ggcaatattg ttatgtgcgt
     5401 caaggaaaaa gctggtacta ctagattcca gaaaatagta actatgattg aggaatctga
     5461 aaaactaaaa tcttctgtag agagtaaatt tgaacatcta gcagatacat tagttccata
     5521 cagcttttta ggaagtatat taacctatgc aattactaga aaccctataa aatcactctc
     5581 tatattaatg gtagatttct cttgtgcatt aaaactctct atccctattt cagtactatc
     5641 agccatgaga gaatgtaaca ataacaacat tactgtaaaa ggtggaaaat tccttgaagg
     5701 tgttgcatgt gcagatacta ttgtatttga taagacaggc acattaacaa aagctcaacc
     5761 aactgtttca gatataatta cattccaaaa ttataataag gaggatatgt taagacttgc
     5821 agcttgctta gaagaacact ttccacactc catagcaaat gcagtagttt acgaagctga
     5881 aaaacaaggg cttagtcaca aagaaatgca tacagaggta gaatatatta ttgctcatgg
     5941 catttcaaca aaagttgatg ataaaaaggt tgtaataggt agcaaacatt ttgtatttga
     6001 agatgagaag tgtactatcc cagacggtga ggaggataag tacaacaatc tatcagatga
     6061 gtattcacac ctatttatgg caatatcagg taaattatca gcagttattt gcataaatga
     6121 ccctttacga aaagaagcaa aatatgtaat ttcaaattta agagaatgcg gaataaaaaa
     6181 gattgtgatg atgactggag atagcgaaaa aacagctaaa tctatagcaa gtaaagttgg
     6241 tgttgatgaa tattattcag aagtcttacc agaagacaaa gccaattttg ttaaaagtga
     6301 aaaactcaaa ggtcgcaaag taattatgat tggtgatgga atcaatgatt ctcctgctat
     6361 ttcagaatca gatgtcggaa ttgcaatgag tgaaggtgct gaaatagcaa gagagatttc
     6421 agatattacc atatcagcag ataatttgaa taatttaatc gttttaaagc agattagtaa
     6481 taagcttatg aaaagagttg atttaagttc taagtttatt attggcttta atttaggtct
     6541 gattttactt ggtgtaggtg gatttgttag accaagtaca tctgcctttt tacacaacac
     6601 atctactgtt ggaataagtt taaacagtat gacaaattta ttggaaaaca ccaatactta
     6661 taactaccat taatctccat tacataaaac atatgatata aaaaatttat aattcatctt
     6721 tttaaaagaa tatgtcttaa aattagcttt tttctaatca aaattatata aagcatactt
     6781 tacaaatttt aaactcaact tatttctatt ttttacaaaa aaggagatga ttcaaatttt
     6841 cattttgaaa catccccttt tgtaaatttc tttaaaattt atatattaat tatattttca
     6901 accaataatt gtattttcaa ccaatctttc ttcatagcat tttaaatcat tttgctttag
     6961 ataattaaat tcagactcta cataaatacc acagcctacc aattcaattg tcaaattagg
     7021 tatattttcc tttagtatac tagtctgctc ataaataatt ctttccaata aatcaacttg
     7081 taatatagaa aaatgcttca taatctcccc atcactatct atatctttct tgatttcata
     7141 ccaactcttt gacaaaattc ccttcaaatc aatataccct agactcctca atatatctat
     7201 actatcgctc catgcatact tactaggttt atcaaagtat gattctagtt tcttcttctg
     7261 ctcatttgta agtgaatcat aagaaagctt cttattaaaa tgtgccttca aagaaatctt
     7321 agccatagaa tatggacttc taccagagtt taatcctgca tttttgaact tttcaattcc
     7381 tttatcttct actgaagacc atattgagtt tattgaatct gaatcattgt atttaatatc
     7441 aagaccatgt gtaatattta tatagttttg tggaaataca tattgataat agacatcttt
     7501 tttatcatca tatagagaga agtatccact atcatataaa tgaatatgca cctttacttt
     7561 taaactatcc tctaaaatat ttcgtctaag gttcgggata tttgcataca tggttacata
     7621 ttttatggca tcaaagtttt tatttaatgg aacttcaaaa ctaatttcat ctcctgtcaa
     7681 aagctttttc acttcttctt cattacaatc atatagagaa tatgtatttt caaatcccac
     7741 acgtgatttc ccatctaaac tgcctgttaa tgctaccttc aaaatatggt tatctgtttt
     7801 ttgccattgg taagcatctt ggtcaagaaa ctctctaatc tgtctatttt gctctttcgc
     7861 ctgatttata acctcgtttt catcttctgt aatccctaca tggcatctat ttaagatatt
     7921 tactatattg cttccaaatg ggaatgtcca tagttgaaaa gctgctgcct caacctgaca
     7981 caaatatcta acctgattta attcaatttg atggataagt tttttctgat attcattcat
     8041 ctgattacca ctatctgaca tttgataaat caattctccc attgcaagat tatctttttt
     8101 cttatcaatc ttatcagtaa tgataatttg agtttccatc atatcctgta cttttttaaa
     8161 tattatagaa atctcctctg agttttccat ttttaagctt ccaaacttcg tgcttaattc
     8221 agttaaaact tccttcatct ttaatttact tatctcattt tcaaaaatat cttgattttt
     8281 aactgtacta tcgaattttt ctacaaatgg tataacagat tctttcaaag ttttatcttt
     8341 aaattccacc atttgagtat tcaattcatc taatttctta atattatttt ctttatcttt
     8401 aattgcctct ttaactacct ctattttact ctcaaaacta gattttacat taagacaatt
     8461 attaacacca ctaatcgcag tatttataag agaacaagca gaacttccaa tactcaatgc
     8521 atttttaatt ttagatgtct tttgctgtct ttcaatagct tgtttacttt tctctagtgc
     8581 agctaactta tctttttgct gtttattatt gtaatttgcc tccaacatac ctatttcttt
     8641 tttctggatt tttgtgtaaa tttccttata ctcgctttca cttaacccct cttttgctct
     8701 ttgaatatcg tcagctttgt ctgcatagtt atcatcatct atagacttaa ctataatctc
     8761 cttaatttgg tcaaatttag ttcttctttc ttcatcaaca cctgccaaat tataagtcat
     8821 tttatctaaa gcattttttc tatcttcact tagctgttct ccaagtacaa atctcatacc
     8881 atcagaatcc aatttaaaat ctgaaaaatc aaccatcctg ttagtccatt ggtattcctc
     8941 ttctttagct gaaagatttt ccttcaaaga ttttgcactg tcaaatgccc ctagacaagc
     9001 ttgaccaaca ccactaaatg cagtcagtaa actcaatgcg ctttgtattc cagaaagaat
     9061 taactgtgtt ttcatttgtt cctcaagttt tgcctgtttc ttttttagtt cctctatgtc
     9121 ttcttgttca tcttctttca tctttataat ttcttgaatc aacaggttca tttttgcatt
     9181 aacagaaagc attttattct caagttcatt ttttaaaacc tctatttgtt gatttccaga
     9241 ttcaatttga gttaggatac tttccttata tgtattgaaa tatccttctt ttaactcatc
     9301 tttctttcct tgttccaatt ctcttaaggt cttatccaga tagtctgtca aagaacgaat
     9361 atctgtaaca cgatttcctc caatttcact ttcttcaatc atctgcacat aaaatgctgt
     9421 cttctgctca agtgcaaata aaatcatact ccattcgcta aaattctgat tttttcctac
     9481 aaaagattct attctatcag actgcatcaa tttatttata aggtattcat agatttcctt
     9541 tgcctcttta taaaattctt tctttatatt catgtcatcc atagaaagta ctgctttatt
     9601 tttcttctca aaactatagt acttctgaag tatttctcta tttaattgca tctctatttt
     9661 ctcaactgca taaaaaattt cataaatatg tgaaaattct aaaatatcag cttctaaaat
     9721 tcctactgca cacaacagtc taagatttct ataaccttta attccagaaa aaccaaatct
     9781 ctcgaaaaat tcatagaaga atgtatctat tgacaaagaa tactcctgct ttaacaattc
     9841 cttttctttt agtgcatctc cagagtgacc ggcttttccc tctgctccgg ctgaacctga
     9901 atcttcacgt ttgctaattg tccagtcctt atgttcttca taaagagtat ttaatttctc
     9961 tccatcatct gctgcttgct tctgatttaa agcatgatta aacacatatc tatcaaaata
    10021 atagtagttt ctatcactat tatccattgg aggagaggta cctatatatc ttattgtttc
    10081 ttcatatata cctctaattc caccaagacc tcctgcacca ccagctcctc cagagcctcc
    10141 ttttcctgct aaaccatgat ttccatcttt tttacttata gcacttttta ataaaggagc
    10201 ttttccaagg agataaacct gtccagactt gcttccaaga cctgcatttc caccattacc
    10261 tcctgtgcct ccagttccac cttgttttcc tttttctgct tttacaacat agtattttgt
    10321 acctttaaca ttagcaaatt cttttgactc ttttttagaa cctattttag catttgcccc
    10381 agcttctcca gttatccctg tatctccttt ttttccatct tgtccatttc caccacgtcc
    10441 accatctacg taaagtttaa gttctcctct tttttctatt tctttaaaag ataatatgat
    10501 atcacctgaa gtacctgcat tattgccatt tcttccattc attccgtcgt aaatagaact
    10561 ttctccaacc aatttttctg catccttacc agatacgttg attgaataag tcccttctgg
    10621 tatatgtaat ttttctgtaa gtagtacaat attcttacct gagaagactt ctttctccat
    10681 attacagtca attttcaact cacaatctcc atacatatat atagatgaca aaatattaag
    10741 ttgataacca gatattattt tagtcaaatc cgataaattc actttaggta taggaatata
    10801 tatagaaagt acattttctt tctcatatga ttttatatat gtacaacttt gaatcttctc
    10861 tatcctatac tctgcatctt caagcttttt ggcttcttct tccctatatt cttcttctgc
    10921 tatccaatat ttgatatctt ttaatgtatc ttctaaagta ttttttagca atgattttaa
    10981 caactcactt agaccaacaa tatgagtctc actacagtaa ctatttaact ctaaaagaag
    11041 acgtgtttct tctaatatat tcactttctg tacgccatca ccatatgaaa gttcttgtac
    11101 aaactccata agctctttca tattattagt cctactacat aaatctgtat acatcttatc
    11161 taattgaatc tttttatctt ttagactatt tatagaagat agaatggaaa tagaatcttc
    11221 catacctttt ttaacacttt ctatataagg aactaaaagt ttttctaggt ctttataggt
    11281 tacatcaaca gctttttgta tttctatttt acaagaagct gtaagcatca atcccaaatc
    11341 tgttttttca aatgtttcag gtagattttt catttcatcc aacaactttt ctggctgttt
    11401 atctagtgga ttacataatt taatagatac accatctgat aatgctacat ttaataagta
    11461 cactaattcc ttacaaccgt cgtaatcttt ctcttgacta tctaagtctt cttttgcttt
    11521 ttccaatata tttcttattt tttcttctgt tacattaccg attagtgttt taggtatttt
    11581 attaataaga aagaagaaat tttctttata ctttgcataa tcaccaagca tatctttcaa
    11641 atttttgcct gtttctatca ataatgtatg tctagagtcc agtagggatt gatagtctaa
    11701 gataactacc atccctttca cctttgaaga tgtggaaata gtttccctta caagcatagc
    11761 accagcaatc atatactctg ctccacggtt gtcaaaaaaa cctgggcaat cacataatga
    11821 aaaatctcta tttgcaatat ctacaacttc tggacataaa gtcttagaat atacaccatt
    11881 tccaatttcg acagctgaat cttttgcagt tatatatatt tgtccagtct cttcatccgt
    11941 tttttcttcc atcacacagc cttttaaata atttatacaa gtactctttc caacgcctga
    12001 agcacctagg aataacaaaa ttgacttttc ttttaagtca tattttctaa gctcgtctct
    12061 tccttcttcc aaaaggttta cgatttcact ataaagttta tttgccatac atccatccct
    12121 ttctatattt cggaacaata gccttgatat ttttctttaa taagattctc ttctaccttt
    12181 gaaacagctg ttgataactt agtatttgga gcattaaatc ctccattgtc tcctctatct
    12241 ccatattcag cgtattctct tgctggtcct gttttacctt cattccagct tccaccacta
    12301 aattctatat gatatttaat tatactatct aacttataat cccaacttgt aaaatatcct
    12361 gtatagtata cagtcttatc tataccactt ggagaaaatg aaagtgtatt atatccgtga
    12421 tagccaccac ttcctccata tccacctaaa cctggtctac catttggacc tgcttctcca
    12481 tctttcactg ttatatcaca atgattaatt attctatttt tttgttcctc tgaatctgaa
    12541 atgaagtaaa tattaccttt cttaccagca tttccacctc ttccagcatt tccaccagct
    12601 ccaccttttt cacctttttt gccacttgta cctttttcaa aatacccttt aaacatctgt
    12661 ccgtggaaat aacttgtata tcctgcatca gctccattac ttccagaagc tcctgtttca
    12721 ccattttctc catctattcc tttagaacca tttcctccat ttgcaatcag tgttagacga
    12781 taatttctaa tttcttcttt aatatataag taaatattac ctgcatctct accatcttca
    12841 ccatttttcc catacataga attatctaca agttctccgc tctttccact tacattaatt
    12901 tttacattac tacctacatc aagattgtta gaagcaagaa taatattttt ctctgatgca
    12961 aagttcattc caaggttatc atccatataa atagtatctt tagcaaagaa cataaaagta
    13021 gaaacattgt catctacttt tctatttttg aaatattcca atacactgct aattactaag
    13081 tttggaatta atgctcttat ttcaatacct ttcttatcat taatattaat tgtttttact
    13141 ataaatggat ttaaaatgta tttaccaata aattctctaa ttatctcatt accttcttct
    13201 ccatatgcac ttaatcttgt tatactgtct tctaactctt cattttgtgt aactgtaaca
    13261 tttgtcaaaa ttgaattaaa atcacttaca ctatatacat aatccttttt atttgcaact
    13321 tccattaatt tttctctatt tggtaatgta aatacctgtt tttgcacttc ataagaaact
    13381 aaaacttttt ctaaattctt tcttattata atgaagtttt gttccattat cttcttactt
    13441 gccttttcta taataaattc catatgtaca gaaggtaata aaatttcccc agttccatgt
    13501 tctgtatatt tacttaaagc atcaattata tctaagtttc cttttatctt attttgtaat
    13561 ttcatgcaac tatcttgtaa gaataatcca ctttgtttgg ctaatacgtt gataaaactc
    13621 tctatagtaa gacttgttgt actttccaac cagtttttaa atacttttac aacctcatca
    13681 tattttgcta tttcttgaat cattgttata cttccaataa tattgataaa atcttctgta
    13741 tacgccttaa cataatcttc taggctagat acgatattgt tttgaatttc ttttatcaac
    13801 gtatctaaaa ctaatcttgc atctgcacta attggatatt ggaatgctga tgtcttatct
    13861 ttaacttcat ctaattctag tacttgcttt aataagcctt ccctctcatc tgatgcaagt
    13921 ggcttacaaa gatgaatatt ttttccatta tcttttagca attcttcaaa taaccaagct
    13981 ttttcctcta tattactgtc taaattttcg cataattgtt catattttct ttttataaca
    14041 ttatatattt gtttttctgt tcttcctaag aaactttttg aaatgaaaaa agttatacta
    14101 cccttaaaat tttctttatg aagacacata tttaactgtt ggaacaggtc tagtactttt
    14161 gtaagtctag aatctaatat atctgcttct ggtatcaata caattactgc acatatagat
    14221 gcagaatttt taaatacttc acctaatgaa actgctgcac taatatcatg ggctactccc
    14281 ctattgtcgc taaaacctgc agtatcacat aattttgcat ccattccttc tattggtttt
    14341 ctcatattta caatgttcgg gtataaagtt tgagaaacag ctcctgaacc aatctctgcc
    14401 acagggtcta agcaatcaat atatgatata ccagtatctt catcttctac ttccatcatt
    14461 acacatcctg caagatagtt aattgcagta cttttgccac atcctgtccc accaagaatt
    14521 agaattaaat tttgattttc agccttattt attgctactt ttccttcatt taataaaagt
    14581 gttatttctt ctaaaagttg attgttattt tctggcattt attttccccc ttggttatat
    14641 attttattta aataaagttt aatcccttaa gtagattgca aagtttttag actatattta
    14701 aatttgtttt ttatttttta tttttaataa atttgcattt tcactaaata attattcttc
    14761 tttgtttatt aaaataactg tgttgtataa tataatcttt atcaacacag ttattttatt
    14821 taatgcgctt attttattgt attttatgta atacagttgt tttttatatt atatgtccat
    14881 tatttttcta tggttattac atatagattt ttaattatat ttgtaccatt aatttaaaca
    14941 ttcctatact actgcttaag ttttacacct ataccagctt gaatatttta tttttatttg
    15001 cttaaatagt tcaactatac tggtttaaat aggttatctt tatttgctta aatagttcaa
    15061 ctatactggt taaataggtt atctttattt gcttaaatag ttcaactata ctgatttaaa
    15121 taggttatct ttatttgctt aaataagttc aactatactg atttaaatag gtttccttta
    15181 gtttaaataa ttcacctata ctggtttaaa taggtttcct ttagtttaaa taattcacct
    15241 atacctactt gaatagttca cttttatttg cttaaattct ataccaatac tggcttaaac
    15301 attatactac catgattgta ttgtctatct tcaactacaa taaaaacagg ttctaaatct
    15361 ttagtagatg ttatttttaa ttctaaaaaa atattatcag ttggtaatat ttttacatca
    15421 taattattta aattattatt cgtgatacta ttaaatacat caccttgacg ttcaaaaaaa
    15481 acattatcaa ctattacaaa ataaacatct tcttttctac tattttcaac ctctatagta
    15541 ttttgtttag ttatatttag tctcatcttc cacctcctat taatattact taattatatt
    15601 aatacttgta attgttgcat tatgttcatc acaaggaaga ggtttaaaaa caactatctc
    15661 tgctaaataa ttctgtggag gatttgtaac tgaagtagca ttgcaaataa atttaaaatt
    15721 tgttcctgct acaacttgag tagaaacaat aagtggttca taaccaaccc cttctaacat
    15781 tcctacagct tcattaaata cttttaaatc ttcttcttcg acagctctga attttgacca
    15841 tccaccaaca aaaagactca tataaaaacc tcctttatat atatatttat ttatatatag
    15901 tagtaccaat tttctcaata ttcaatattt tctgtgtaac tggtcaatga aaatgcataa
    15961 ctggataaaa atacttataa aataacttaa ctttacatat aaatagctta ctttacatgt
    16021 aataagatta ttctacatgt aataagatta ttctacaata tgaaatgcat cttgttttga
    16081 atatattcta aatacaataa tggatatttt caattattat aattagaaaa tatccattac
    16141 ttaacttgtt ttatttaaaa tcacatagag actttattat tttttttatt gcatgaatag
    16201 ctatttcagg tatcataagg tgatataccc cctccttgaa accacaaaaa acatgacaaa
    16261 ctttacgaat cttgtcttaa aaaactacag gtacattcct tatttgtgga ttggagtagc
    16321 cataacaagc aaattttaca atttttatga tgacaaaaat caataaaatc gcttagtata
    16381 taacacgaaa tactacttgt tactattaag aatagttaga taggaagtat gcattataca
    16441 aataaaggaa tcaataaaga aagttaaaac atccctacaa attaaaaatc tgttacattt
    16501 ttctatattt aaacgttatt tacttacaat tggagaaata acaggttttc cttctcggtc
    16561 aagtaaaggc gtaaatccgg ctgcattgcc ataatagtgg aatacatagt tcacacctgt
    16621 ttctttatcc acccaaatct ccgttgcatt tattttccct tgtgaatata ctttttcaaa
    16681 tctatctttt cccattttat aatcctccat atttttgatt ggtctatgcc ttcttcactt
    16741 aagtagaaaa aatacataac ttattttttt aattctaata tgagcacgta aaaatgtcaa
    16801 acagcttatt taatttcata acttcatgtt actgttcgta accttgtctg tttacttaca
    16861 ctgcattaca gcaccatttt atcctttaca ttattgtatt gcacacagta aaaatgctta
    16921 ctttatggga tttttcaact aaaaaaagga ttttatctcc acaaaacatt tactatttgt
    16981 tacaatatac ctaattttaa tctcatatca acatttaatg aagatataac ctttttcaaa
    17041 tattgtaaag actccttaaa aatattagaa aaagattctg caaatctctc aacatctcct
    17101 ttttttaaat acctaagtat ctcaaaacat acatcaaaac gtgttttcaa aatttcatta
    17161 tattcttcat gaaaaaatct ctctaaatag attccaaata tcatatattg ttttaaatgc
    17221 aaaaatgttt cctgtaatac ataaatttgt gtataatcta ctatcttaca aagtaaaaca
    17281 aaatctggat aaaccttaca ctcttcacaa ttattttgta agtaccttaa atgagtttct
    17341 attttatcta cagctatcaa atccatttta tttcctagta aaagtactac atcctcaaga
    17401 gtaatcgtaa caaactccat agcatccaaa agcaaactca accttttagc tccttcttct
    17461 gtatttatat aatcatcatc atattcagaa aaaagcgtta catatgttcc cttgccatta
    17521 attgttttag caattcccaa ttcatttagc tcattatagg cacttctaac tgttggaagt
    17581 gatacattat atctattaat tatcgaagta attgatggta gacaatctcc tattttaata
    17641 ttgccttcaa aaatttgaca aattacatct gaaacaatta agtcatataa ataacatttt
    17701 tccaacgtta cagaattaaa actacttgta tctatacttt gtggagcacg attttctacc
    17761 attttaagta tggattctct acaagcttta tacatatatg ttaatagttt tttaaattca
    17821 attagattcc catccaatcc atataagtaa gtttttctta cctgctctat gtatttatta
    17881 cgaaaaaagt ctatacaaca attatccaag ttatccaagt tatcgaaatt ataggccaat
    17941 tgtgaaataa tgacatcatg ctgaataatc tcacaaaaat ggtgaatcag gaaattattt
    18001 gttttactta ttagtttatt tatatatttt agcctttgtt ctttaaagac taaataatta
    18061 gaactatttt tttccataca atcgataatc tcgtttaatt cttcaaagtc tttagatgta
    18121 aatcttttaa tattgtacat agcaatagaa ggaaatatta aactaaaaat cttatatatt
    18181 tctgatattt gtaaaatctt ctcatataat aagtcagatt ctattgattg tttactcgta
    18241 ctctggatta aaactggtct agaaccagct tttgtctcta taaagccctt ttctgagagc
    18301 atttttatta cagtttttat agtatttttt gataccatat attcttctga catgcttttt
    18361 atagaatcaa gcctatctcc aatagtaatt ttaccagtat aaatttgttg aattatatgc
    18421 tcaaaaataa ttaaatattg tggttttctc ttcatatttt tcctcttcga taaattagat
    18481 ttattgtttt ttgtaaggta tatttacttt tatttaatag ggcaaaatag ttgcttattt
    18541 tttcctcata atctataatt aatataaacc atttatatat atggtctaag ttttataata
    18601 ctgtaatgca gtaaaatagc atgttgtagc tatactacag caaattaaca taccattgta
    18661 gtatattaat tggaataatt ttaagtactt caaaattcca gcaaaacata tatgtgtttt
    18721 tgatattatg tatattcgtt aatagaatag ctatacttgt tttacataat aaattatatg
    18781 atacttgcta tatgtaatca ctatatttaa tacacataac tattatactt gctatatgta
    18841 attactatac tttatacaca tagttatcat atatgctata tgtaattact atactttata
    18901 cacatagtta tcatatatac tatatataat tactatactt ggacacatag ttatcataca
    18961 tgctatatgt aattactaca cttggacaca taactactat atttactata tgtaattata
    19021 ctatacttgg acatatagtt atcatacata ctatatgtaa ttactatact tgaacacata
    19081 actattatat ttgctatatg taattatact atacttggac atatagttat catacatact
    19141 atatgtaatt actatactta tacacataat tatcatacat gctatatgta attactatac
    19201 ttatacacat aactatcata catgctatat gtaattacta tacttataca cataactatt
    19261 atactttcca tacataatta ctatatttgg acacatagtt atcatacata ctgtatatta
    19321 agatataata ctttttaaat tttatataac acagacacat gcaataaaaa agaaggtatc
    19381 cataataagc tctttgcatg tacctaaata aaaactgtaa aatagaatat ataaaatcta
    19441 atctatttta agtaaataca atttcacttt aaaagaggat gtactatgaa ataccatata
    19501 tttttaatca taactactat attaataatc gaactatgta acatttacat atgcaaaata
    19561 gcatcttttg gaaacaaaaa tataactata cataagaatt acaaatatat ttttttaata
    19621 aaaccattaa ccttcttgat aataatattc acaaaattac cattaccact atattatata
    19681 ttgttttaca tagtaagtca taaattgctc ttaagcagaa aaagttctac taacaaccat
    19741 tttattccca atatggcagt aataagtttt tgtattttac accttattac tgtaagtaca
    19801 atatcacttg ttaaaaatac aagtccagat ataatatttg caaatatgac ctataagtta
    19861 attagtattt taatagcttc tattttagat tttatcttat ggtactctat gaataaaata
    19921 aaagagcata tttatataat aactcaaaat caaatagagt tcagtctatt tttaaaattt
    19981 atctggttca ctttaggata tatattattt gatagtatac aaattacatt tgctccacca
    20041 agttctctaa cttcctactt tatattggga agtaacatat tattaatctt acaactaatt
    20101 atattcatca atcatatata ttccattgaa aaaaatattt atttagaaaa agaacataat
    20161 agactaaaaa tgataaaaca agaacaatta ctaaaagtaa atttattaaa gaaaaaagct
    20221 aacattgatg aattaacatc agcatataat cgaaaatttg cttttgaaaa aatacagcat
    20281 tacattgata acaatttatt attttcattg atatatatcg atttggataa attaaagacg
    20341 ataaatgata catatggaca tttagctggg gataactata ttattaactt ctcaagtata
    20401 gttattgaaa acttaggaat agatgacata tttgctagaa taggaggaga tgagtttata
    20461 gttattatgc ctaaatctaa tgaaaacacc acaaaagaat ttatagagaa aataagtaaa
    20521 attatggata atacgatatc ttttagctat ggtattgtag aagtttctag cgaaaacaaa
    20581 atgactgtag aagaaattat taatattgct gatattagaa tgtacactaa taaacaaaat
    20641 aatcataaaa ggaacaataa ctaaaatgaa tatttacatg agcttacttg tagtctcact
    20701 atgtttttta tcttattatc tctatcatta taattttttt aaatatctgg acataatgat
    20761 taataactct aaaaataaat acacagtata tattatatat tctatattta attatttaat
    20821 ttttattatt tgtacttatt taaagtttca tctaattata aattggacaa tttttatgtt
    20881 gattttattc atacaaatta aagtaactta taaaatctcc acaataaaaa acatttttta
    20941 ttcactaaac tgctccatca ttggtttagc aataaatata ttttttaggt ctttaatgtc
    21001 aatagtgtta aatatgccag catatttatt tgatagtaat tctattgcaa atatttacag
    21061 agtatttcct atatcattta gctttatagt tacaggacta tatttcagtt ataaaaataa
    21121 taaaaataat aagattaact ttgaggcagt tttagaggac aaaaaaaact taattttctt
    21181 attgagcctt atgtttggaa tgtacttgta tctatgtttg agtttgtcaa tatactatac
    21241 tgttggaaat gtattgattt taaaattata tggaatcaag tctgccataa tagttttggt
    21301 aggtaactat attgcagaaa gatatagctt tagaattact caaataaaag gttatgatat
    21361 taaaaatcaa atagaatatg tagaaagtgt aaagacagaa tatgagatta ataaattgaa
    21421 tgatattgta tatacagatt tactgacagg tttctacaat agaccttttg tgaatcaaaa
    21481 actatcagaa tggacatcaa atcactacaa atttacctta tgttttactg atttaaatag
    21541 cttaaaacct gtaaatgata aatttggaca ccaatttggt gataaataca tatccactac
    21601 tgctcaaata ataaaaaaac ttataaatgt agaaaattcc ttactattta gatatggtgg
    21661 agatgaattt ttattccttt tacagaatac aagttgtgta gaagcagaaa agataatgat
    21721 taatataaat tatgaattat caaaattaag taatactgac gagtatcctt atgctctttc
    21781 cataagctat ggattagttg agtgggatgg aatatccgat attgaaactt taatatcaaa
    21841 ggcagattct ttgatgtatg aaaataagct taaaaataaa tctactttaa actagctagt
    21901 taagatattc tacaaaatat atgttataag agagtactaa gaatatcaaa atatatagat
    21961 tttgcaaata ttgaatacag tttactaatg aatgcactgg atgtaagtgt tagtaaacac
    22021 ctattagatg aacactttac tgttgtttgg gctaatgacc gttattatga aatgttcagc
    22081 tatacctagc taaaaagtta aaaatgacca ctgtagccga gggaatagag accagttttc
    22141 aaaaagattt cttgcaagaa ataaactgtg atatgttaca aggatacgtg ttctctagac
    22201 ctttaccaat aaaagacttt gaaaaactta tgtttcaaaa ctcctccaat taacaatata
    22261 aaattgctta ttataagtga tattattgta tcaacaaata aaggaattgt ctcaaaattg
    22321 attttttcta atcaaatttt tattttgaga cattctcatt tttttgcata agaaaatacc
    22381 caccaagcta cggtttttct taccgctgtt cggtgggtat tagtagtatt atgaaatctg
    22441 aaaactttaa gtattactac ttccgctaac gcaatcacaa aggtcgaaag cttcaaagcg
    22501 aaaacaggct ttttactcat caaacgtcac cgtacctgcc aacccgtcca ccgttatcat
    22561 ttgtccgctc ttaatagttc gtgtggcaat gtgtgtagcc ataacggctg ggatgccata
    22621 ttcacgtgcg acaatgcttg aatggctaag aggaccacca atgtccgtta caatcgcact
    22681 tgcagatgaa aataatggtg tccatgctgg agttgtggta actgcaacca aaacacttcc
    22741 aggttgaaag ctttcaaaat ctgctggact attcagtaca caagctggag ccgtcacaac
    22801 accagtactg gtaccaatgc ccgtcaacac aattttccca tctttctgct tctgttgtgc
    22861 ttgtgatata gtttttttgt ttttctctgg caacttggat ggtgacatat aacccatgta
    22921 ttttttaagt tcagcttttc gaacaggtat tatcccgttc atatcagata gagacttgtt
    22981 tttatccaac tgctctataa gtacctccaa ttccgatttt gtgagccaat aaatatcatc
    23041 taaatgtgaa atagctcctc ctcgtatgaa tcgttctgag atttcctgaa acatacaacg
    23101 aatcagagga tgtcccattc ccatcaaata aatagcattt tcacgcatag gagaggtttc
    23161 ctgtgcccaa tggagcaact taaaaaatag ttttttacgc aatccaccta tgtgttgtaa
    23221 aatctcttct tctgcatgtt ttctacgctt ttcaaacgtg gtctggcgta aaaaaggact
    23281 ttcccctttt ccttccacaa atgtttttac ggattcaaaa gttggtgtaa gtgtttcctg
    23341 cggtgtggaa tgcgcaaaat caaactcata agcggtacga ccaaactctt taaagtactt
    23401 attgattcga tttttccatt ctatccatac ttcctgtgaa actccaacag gcacaactga
    23461 agacatgaaa tcttctgcta tctttattgc aggactgttt tgcagataaa ggttgatgct
    23521 gttattttgc tttacccatt ctgaaatacc ccacaactcc ttttccgatt gcagaacaat
    23581 cgtatcaaac ccaagcagga aaacggaagt atccgttata ccagcacgtc gaactgctcc
    23641 ttgaaataat tttgtaaata atgtttcact gatagaagca gcaggcaatg taagctgaat
    23701 ccttgtgaaa taaatacatg cggcataaaa tattgtctga ataccctcca taatttgatg
    23761 ggcgttcata gtatgcaggg gcttttcttc ccattgttta atagcatcct catatccttt
    23821 tcgtgccgtt tcccagcgtg caacgctgtt cataagtgtc ctacgtaaag agcgtgggga
    23881 aagggatttg atagcaatca aaagtggctt tgatttagca gaaagataaa catatccatt
    23941 aataaccgta tatgccccgt tttttggtaa taattttttc gcacttttac caaacatatc
    24001 tatccataaa agctctgatg cacggtttac gatttcaaga ccaagtgtgg cgaacaaagg
    24061 tgtaacagga tttggcaaat gttctgccaa acttcccttt gtgtatacaa catcctgttc
    24121 tggcaatacc cattctggtg gcagaacagt aattggacga gcctgaacaa tgtacaattt
    24181 atctttttcc agtgcccact ctacatccat aggcatttga taatacttct caattttctt
    24241 tccaagctgt atcagttgca ttacctgatt acgagtaaga gcatattttt ttctcaacct
    24301 ttcaggaacc atggtttctt ctgttccttc tgaagtacga accgtcataa tctctttatt
    24361 tgccacttca tacgatataa ttcgttcgga gtccttatcc actacgattg tatcgggtgt
    24421 aactaagcta gaaaccaccg cttcaccaag cccccatgca gcgttaataa tcatttcgct
    24481 acgtctacca ttgattgggt ttaacgtaaa cataatacca gatgaatcgg aaaatgcaag
    24541 cttttgtact acaacagcaa gtgcgacaat ctcgtgcttt atattattct tcacacgata
    24601 agcaatagca cgagctgtcc ataaggaagc ccagcatctc tttacagagt caataacttt
    24661 atcttcacct tgtatgttaa gataagtttc ctgctgacct gcaaaagaag cgtcaggtaa
    24721 atcttcagca gtcgcagacg aacggacagc caccgatatg ttccctaatc cagcataagc
    24781 cattttaatt gcgtccgaca cttcctgtgg catttctcca ttatggaaaa gctcccctat
    24841 tttcttagat acatcttcaa gttggctggt attattggaa tcaataccat ctagcagttt
    24901 attaattcga gactgaatat ggttcgtctc aacaaaaatc tggtatgaag cagtcgtaac
    24961 atgaaaaccg tctggcacag ggatgcctgc tgtcaatagt tttgataaag acatcccttt
    25021 tccaccaaca atttcaatgg ttgcttgttt atgttccagt ggcaagacat aataaatcat
    25081 aatcattcac ctccatcatt cataattccg ttcagaaata tattcattgt ttcatccaac
    25141 attttttccg aactatccaa tggtcgtgac gtgtagctga ttgataacat ggagttaatt
    25201 aacaaacgtg tcacaagagc ggtatccgtt ttgcgaaaga tgcctgtggt cacaccatta
    25261 tcaattaccg attttataat atcttgatat gcataacgag catctttaag tctctttcga
    25321 tactcttctt ctaaataatc agattctgta tttaaccaca tcagtacagt tctatactgc
    25381 tctggaaatc taagatgatt aagcatgatt tttctaaggc actgttgtgg tgaaggttca
    25441 ccatcaataa tcctatgaac ttgttggata gttttttcta tttctttctc aactgcatat
    25501 acaacaatct cgtctttcgt tttaaaaaaa tcgtatagac ttgactttcc catgttggct
    25561 aaaactgcaa tttctctcat tgatgttttt tggaatccat tttcagccat gagactcaaa
    25621 gcaacagcaa ctattttttc tcggcgttct gcttgttgtt cgggtgtaag cacaattcct
    25681 tttggcatag tgcgatacct ccttttagcg accactggtc gtttcttttt tatttatcat
    25741 acagcaacca acggtcactt gtcaaggtta atttttttca ttgtatatgg tactcgagat
    25801 aaaaatgttc attttagaaa ttactctatt taagtagaaa taggcttcat cattagaaag
    25861 caagactata aatttgagat atttatcatg ttcaaatttc atcaatatca aagtttaaaa
    25921 tattaataaa aaaagaatta ctaagaaata acatataaag attcaaaaaa ggagttgaac
    25981 ttaaaattca attacaaaaa atcaaattta agacaactcc tttattcttt atctctacta
    26041 ttctttatct ctatttattt attacaactc cctaacattt accactactg ccttaggtct
    26101 agtcatagcc tcaattgaat acttaacacc ttgagttccc ataccagatg cctttacacc
    26161 taaaaatggg aagtggtctg gacctctttc agtcttatta tttatttgaa cagtaccaac
    26221 ttcaagttta tcagctatat aaaatgcctt atcaatatca cttgtaaata ctgatgattg
    26281 aagcccatac tctgattgat tagcaatttc aattgcttga tttatatctt taactcttat
    26341 aattggaagt actggaccaa atggttcttc ccaagcaatt ttcatatcaa catttacatt
    26401 atctaacaat gttggataga ataaattatt ttttctaaca ttgcctgtta ttaactttgc
    26461 tcctttatgt aatgcatcat caaccaaccc ttgaacaaaa tcagttgctt tattatctat
    26521 aagaggagtg ataactactt catccattgg atttccaatt gtcaacttct ctaccaatgg
    26581 ctttattttt ccgactaatt tatccgccac actctcttgt actaaaattc tctttactgc
    26641 cgtacatctt tgtcctgaat atgaatacgc tccagatact atattcttag ctgcaaaatc
    26701 taagtctgca tcttctaata ctatagccgc atcttttcca ccaagctcca ataataatgg
    26761 taccattcca gatattttag atatatgctg accaacttca gtactaccag taaagttaat
    26821 aaaattaatt cctttatgcg ttacaacata atcccctatc tcactacccc tacctgtaat
    26881 agtattaagt actccatctg gtatcccagc ttttctcata atttctacca catgaagtgc
    26941 gctaatagcc ccttgtgtag caggttttaa tacgactgca tttccaccaa taagtgctgg
    27001 agcaatcttt gacattgata aatttacagg ataattaaaa ggagatatag ctaaaacagt
    27061 acctaatgga acccttgaaa cataagacat cttatttctt gttccaccag ggaaattatc
    27121 tccactaatg gcttctccct ccatattttt tcccacatca gctgtgtatc ttaaaaaatc
    27181 tgctgttctc tcaacttctg cccttgcaga ttttatgtct ttggctattt caagtaccag
    27241 tatattagct atctcatcta tattttctaa caataaatca gcagccttat gaaatatatt
    27301 gcctctcttg tatacaggca tttcagccca tacttttata ctctcttttg tgttttttat
    27361 aacctcatct acctcatgtt ttgtcataga ttgtactttc ccaacaagag aattatctat
    27421 tggtgagtaa atttctattg gctttctcga attagattct acccattttc catttattaa
    27481 atttttatat acattttctt ttgttttaag ttcattaaac atatttttat tcctctctct
    27541 gatataactt tgtgtattta aattatagcc atttattcgt tatgtaaaca tttctttttt
    27601 tcataaacgt ttacctataa aaaaatttta agttaacgtt tttctacatt cttctatttt
    27661 aataacatac tcgctccaaa tctatatagg tcacacttta atactaatat atcaatatac
    27721 caatatacca atataccaat ataccaatat aaatattata aacataaatc acttgacaaa
    27781 tttataagta gacaatatta tatatctatg actcaaaata tttttaaagt catatatatc
    27841 atatatagac agaaaggatt gataaaaatg gctaaaagtt ttacagaaat agaaaaagac
    27901 aatataagaa aaagactaat ttcagaatgt gaaatcaact ggtctaaata tggatacaaa
    27961 aaaactaata ttgatgaact ttgttcaaaa tcaggaattg caaagggttc tttctataca
    28021 ttttttgatt caaaagaaaa gttatttttt gaagtattaa atggaatcca aaacagactt
    28081 atatcatcag tagatgaaat tttaagtaac atgcctccaa aagaaggctt tgcaaaatcc
    28141 ttaaaaatgt tatatcgatt atatgataaa aatccatttt tatattcacc aaataatcct
    28201 gatttcatca gcctaataaa taaactacct caagatatgt ttttacaact tgagtccaat
    28261 aacatacaaa gtttttacga cttaattgag agacacaatc tcaagttgaa gatagaaaaa
    28321 gaaaaagttt ttggtgtttg taatgctcta ctatcaagtc tgttggtaaa agaaaatatt
    28381 gaatataact atattgaagt gtttgacttt atggtggata atcttgtaga acacatactt
    28441 gaataacaat ttaaaataat ttttctaagt atttttttat actaaatagg attaatatga
    28501 ttgaattaat gcaaaaaata aacaatataa tttataaaat aaatgataaa ctaaatatca
    28561 cacaaaactt atagacccta gagcaaaccc attccactct actctaagcc atctataata
    28621 gtttgtatat ttctaataat attagatatt aaagtaagaa aaaaattcct tataataatt
    28681 gctattatat caattattgt aaatgtttta ataatcttag ataggtaggt acatatatgg
    28741 taaaatcctc gaacactttt aataaaaact tcaacttgat gatattaggt caaataatct
    28801 cattgtttgg tgcatcaata cttaaatttg ctttatcttt atacatactt gatataactg
    28861 gtaaagcaga aatatttgct actatactag cagtatcttc aatcccaatt atagtattct
    28921 cccctattgg tggagctatt gcagatatat tcaacagaag aaacttaatg gttatttttg
    28981 atttttcaag tagtcttaca gtactaatct tagcagtatt cttattcaac aataatggtt
    29041 caatattact tgtaggaatt attatgacca tattatcagt cataagcaca atgtatcaac
    29101 caactgttca gtcaagtaca ccccttttag ttgataatga gcatttaatg aatgcaaatg
    29161 gtattgtagc tggagttgca tctcttacaa atattgcagg acctgtatta ggaggtgtct
    29221 tgtatggtgt gattggaatt aatgcaatta tagttataag ttgtgtaagt ttctttctat
    29281 ctgcaattat ggagatattt atacagattc cttttatcaa acaagagcaa aacagcaaca
    29341 ttataaaaac tatatttact gatataaagg atggtattgt tcatatatgt aaagaaaata
    29401 gatttatact aaaaatactt tttttagcta tagcaataaa cttattttta agctctatgt
    29461 taatagttgg tatcccctat atagtaaaaa tcactatggg agctagtaac ttcttatatg
    29521 gtctagcaga aggagcaatt tcttttagtt cactggtagc tgctgttagt attggtattt
    29581 tctcaaaaca tctaaaaatc actaatttgc atatttcctt tattatatgt gcagttatgt
    29641 tcataccaat ggcggtttca gtatatccat ttatattaaa cacaggattt ccagttccat
    29701 ttttaatctt tatagtatca tctatgctaa tattttttac aacgactctt atctcaatat
    29761 atgttataac agtcacacaa ttaaaaactc caaatgaact cttaggaaaa gtaatgtcaa
    29821 ttctttttgc aggaacagca attgcaatgc cccttggtca ggttatgtat ggtaaacttt
    29881 ttgatttatt atcagataga gtgtacatca ttatactagg agttggattt attacattac
    29941 ttatagcatt tgtatcaaag ataacattga ggaacgaaaa tctttagata caaagaattt
    30001 agatataaag atttaatttt cactaatttc tgaatttaaa tgcaaaattg tgtatcagta
    30061 tgttgacgtt ttagaaattg attgatataa tcaatggaaa ataaacttta taaaaattca
    30121 aaatattcag ctagaggagt gataaaaatg agttacatgc caactttaga acaagcatgg
    30181 gaaatattaa gaaaatacaa taaggaagaa tttcatataa gacatgctca aattgtatct
    30241 ggagttatga gatactatgc aaaggagtac gaccctgaaa gagtagaatt ttgggaaata
    30301 gttggacttt tacatgattt agattttgaa atgtatcctg atgaacattg tgttaaacaa
    30361 agagaattaa tgacagagct tgatttagat aaatcaataa tcgattctac aataagtcat
    30421 ggatatggat taactggttc agatgttaaa ccagagcaat ttatggagaa agtattattt
    30481 gctgtggatg aacttactgg tttaattggt gctgctgcaa taatgcgtcc ttcaaagagc
    30541 gtttctgatt tagaattaaa atctgttaag aagaaattta aagataaatc atttgctgct
    30601 ggctgttctc gagacgttat aagaagtggt gcagaaatgc ttggatggga acttgataag
    30661 cttatccaaa caactataga agctatgaga agcttgattc cagagatggc aatatagctc
    30721 ctccatacat ataccataga agttacatct ttaaagagca tttctctttt tgatgcaact
    30781 tctttttata ttttgtagaa taaaaagttt aatattttaa actcactata taataaataa
    30841 tataatgtat aatagtcata aactttctaa ccttaaaagt ttctaataat
//
LOCUS       DAYAOO010000043        30536 bp    DNA     linear   BCT 12-OCT-2024
DEFINITION  TPA_asm: Clostridioides difficile isolate ST8-SSI-h139-18
            SAMN40601845-rid21577343.denovo.043, whole genome shotgun sequence.
ACCESSION   DAYAOO010000043 DAYAOO010000000
VERSION     DAYAOO010000043.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN40601845
            Sequence Read Archive: SRR28438827
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 30536)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 30536)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-MAY-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-MAY-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002157583.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002157583.1
            Genome Coverage       :: 163x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/11/2024 16:19:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 4,038
            CDSs (total)                      :: 3,963
            Genes (coding)                    :: 3,930
            CDSs (with protein)               :: 3,930
            Genes (RNA)                       :: 75
            rRNAs                             :: 6, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 60
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 33
            CDSs (without protein)            :: 33
            Pseudo Genes (ambiguous residues) :: 0 of 33
            Pseudo Genes (frameshifted)       :: 7 of 33
            Pseudo Genes (incomplete)         :: 25 of 33
            Pseudo Genes (internal stop)      :: 11 of 33
            Pseudo Genes (multiple problems)  :: 8 of 33
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..30536
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN40601845-rid21577343.denovo.043"
                     /isolate="ST8-SSI-h139-18"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Denmark"
                     /collection_date="2018"
                     /collected_by="Statens Serum Institute"
     gene            complement(13..432)
                     /locus_tag="ACGI5H_002195"
     CDS             complement(13..432)
                     /locus_tag="ACGI5H_002195"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428147.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HFG9697898.1"
                     /translation="MDTLGERIVYLRKAKNLKQYELEEMLGCDNLSKFERNIRKPNYE
                     ILKSIAEIFNVSVDWLLNGDNLSHKSDLICDSSSNYPLNSINSNEIKLLNNFRKLNDY
                     DKAKIEGMIELKLHEYEKEKDLGKIEYNKNKDEKIDK"
     gene            731..940
                     /locus_tag="ACGI5H_002196"
     CDS             731..940
                     /locus_tag="ACGI5H_002196"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419680.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="HFG9697899.1"
                     /translation="MDARKKWIPFLGVQVKQRLIELNMTQRELAKKIGVNENYLSAIL
                     NGRRTGKKYKSSIYQLLNIEYSEDD"
     gene            972..1181
                     /locus_tag="ACGI5H_002197"
     CDS             972..1181
                     /locus_tag="ACGI5H_002197"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905424.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9697900.1"
                     /translation="MCKLDSDGVIECCRAIDDFITALSNIKSLNMERLNTLTKYSSTC
                     SILLKEGNYEGCTIVYRKMLEELKT"
     gene            complement(1398..1796)
                     /locus_tag="ACGI5H_002198"
     CDS             complement(1398..1796)
                     /locus_tag="ACGI5H_002198"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889162.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HFG9697901.1"
                     /translation="MDTLGKRIAYLRNSKKLTQRKLMDILKFENLGKYETGDRKPNCD
                     ILMSIADYFNVTTDWLLYGKEKVNVNSSVKEDKEDYLHVTNDEMTILNLYRQLNERDK
                     IKIEGILELKISEYKDLKKHSSNNNEDKMV"
     gene            complement(2217..4718)
                     /locus_tag="ACGI5H_002199"
     CDS             complement(2217..4718)
                     /locus_tag="ACGI5H_002199"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438467.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HFG9697902.1"
                     /translation="MFTLNHNTSIKNKDSNPKIFLVLTLYLLGIFMGAIDTGIVSPAR
                     TIIQNSLGVNEKTGIWMITIYTLTYASVIPISGKLADKIGRKYVYLVSIFLFGSGSLI
                     CGLSSLFSNFYILLIGRVIQAIGGGGIMPIATAEFGTTFPENKRGMALGLVGATYGIA
                     NILGSSIGSTILSIFGTQNWKWLFFVNLPICLIILIGGVFCIKNNKSESKEKIDKLGT
                     LMLICIIVSLLYGLMNIDFFNFKNSIQDISVYPYLLTFIVLIPIFIFIENRAKDPILS
                     FEYFLNPRILIVLILSLIVGIGMMGMVFVPQYAENALKINAGSGGYFVAILGLFAGIA
                     APLSGRLIDKFGAKKILLLGFSVSMIGSLYLVLIALKTNTVFSVCVSLIFMGLGMGFT
                     MGTPLNYMMLSNTRLEESNSALATLSLIRSIGTSISPAIMIGFIAHAGLSVQDNIMDL
                     VGKPSTPKIVQLEELENMIDDLKSDPEMAKNLKNVSIPNMNDTSNINMDMTGGKLPKS
                     LLNKVQSADTTNITNITKEISTTMFDEKVPSIITKIQKNVQKGIDGTQSGINGIEDGE
                     NKLNSGIKGVQTGIDNMVKARAGINQGIDGVKKGIAGVDKGIKGMEQGLEKQDEAIKE
                     LTTAYNKIPTTEKTPTDNENNSNEQNQSNTSNSESDDTKNDSTENKNNNSSENKPNVN
                     EQKESLNAQIQQLKKTRDDLNTKLQKNKTQKNELSKKLRTMESQKKELQSKLNNSISQ
                     KKDMEKSLDTMQQQKKSLQAVLAKTQEVKTEIPKAFDKSKLDYINSIENNRTKIENTL
                     QSTLNSGFKQMYITVFCVNLLAFIILLFYKENKTR"
     gene            complement(4723..5265)
                     /locus_tag="ACGI5H_002200"
     CDS             complement(4723..5265)
                     /locus_tag="ACGI5H_002200"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861191.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HFG9697903.1"
                     /translation="MPKILENVKEDILKVSRDMILEEDYSNISIRKIAQRCGISAGTV
                     YNYFNSKQEIIEYITKSEWDLLIRRIEYSNKNTEDYIKKLNIIFTEIRNFINKVHNIQ
                     YNDFLNTFETERFFEMKKHKDDFHEQLSNKVYEALEKESFFNNDKLVCNIIIKMFFSY
                     STYLHIEFEDLKPYIEKLIH"
     gene            5509..7023
                     /gene="glpK"
                     /locus_tag="ACGI5H_002201"
     CDS             5509..7023
                     /gene="glpK"
                     /locus_tag="ACGI5H_002201"
                     /EC_number="2.7.1.30"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905427.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004370 - glycerol kinase activity
                     [Evidence IEA];
                     GO_process: GO:0006072 - glycerol-3-phosphate metabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycerol kinase GlpK"
                     /protein_id="HFG9697904.1"
                     /translation="MEKKYVMALDQGTTSSRAILFNKKGEIVKIAQKEFNQIYPKAGW
                     VEHDPMEIWGSQSGVMREVIETAGIRPEEIASIGITNQRETTVVWSRYTGKPIYNAIV
                     WQCRRTSEICDELKNKGLEESIKEKTGLLIDAYFSATKVKWILDNVEGAREKAEQGEL
                     LFGTIDTWLIWNLTRGKVHVTDYSNASRTMMYNINDLEWDEDILRELDIPISMLPLVK
                     PSSYVYGHTDERMLSGAKIPIAGCAGDQQAALFGQNCVEEGTAKNTYGTGCFLLMNTG
                     SNIVKSKHGLLTTIAWGVDGKVTYALEGSIFIGGASVQWLRDELKIIESAKDSEMYAN
                     RVEDTNGVYVVPAFTGLGAPYWDMYARGSILGLTRGAKKEHIVRATLESIAYQTKDVL
                     EAMQNDSKLKLKSLKVDGGASNNNFLMQFQSDILNVDIDRPKIVETTALGAAYLAGLS
                     VGFYIGRNEITSKWSVEKEFNPNMSEEKRCKLYKGWKKAVSRALSWEKEDELDI"
     gene            complement(7137..7766)
                     /locus_tag="ACGI5H_002202"
     CDS             complement(7137..7766)
                     /locus_tag="ACGI5H_002202"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419696.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008324 - monoatomic cation transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0006813 - potassium ion transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TrkA C-terminal domain-containing protein"
                     /protein_id="HFG9697905.1"
                     /translation="MDKNYTMPIYQKIALDIANKIYTGEIQEDSVLFGRSVLAGKYNV
                     SPETIRRAVKILEDIGVVKSIKGKGVIVLSPDKASSFIKKYRDITNISSYKSTLYNLI
                     DTKSNLENEILDTINKILDYSNRLEIINPLVPVQFTINSNCKYIGQTAAQTKFWQNTG
                     ATIVAIKRGEELIISPGPYIEFLEGDILLVVGDQHIYNSIPMFLYENEK"
     gene            8354..9145
                     /gene="pxpA"
                     /locus_tag="ACGI5H_002203"
     CDS             8354..9145
                     /gene="pxpA"
                     /locus_tag="ACGI5H_002203"
                     /EC_number="3.5.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896287.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003824 - catalytic activity [Evidence
                     IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="5-oxoprolinase subunit PxpA"
                     /protein_id="HFG9697906.1"
                     /translation="MYKVDLNSDLGESFGTYKIGLDEEVLKYISSANIACGFHAGDPS
                     HMEKTVQLAKKNGVKIGAHPGFLDLIGFGRREMKITKQEAKDYTKYQLGALMAFASSN
                     GCNIQHVKPHGALYNMAAKDKELAMGICEAIYEVDKDIILLGLYNSEMINSAKEIGLR
                     FANEVFADRAYDNNGFLVPRNVEGAVIHDTKHAIDRVVRMVKEGTVETLTGEVIHIKA
                     DSICVHGDNPKAIEFVKEIRKRFELEGIEVCPLENIEVCSSENIV"
     gene            9174..10394
                     /locus_tag="ACGI5H_002204"
     CDS             9174..10394
                     /locus_tag="ACGI5H_002204"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419704.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_function: GO:0046873 - metal ion transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0030001 - metal ion transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NRAMP family divalent metal transporter"
                     /protein_id="HFG9697907.1"
                     /translation="MSTKNITDKTKNKKDVGALIGAAFIMATSAIGPGFLTQTAQFTQ
                     DFGPNFSFVILITTILFIGAQVNVWRVIGVSGLRGQDIANKIIPGLGYLVAFLVALGG
                     LAFNIGNVGGAALGMNVMFNMNMTLGTVLSGLIAIFVFMSKNSNSLVDKITKFLALGM
                     IIIVGYVAISNHPPVGEAVSRMVKPENPKGLIFPIITLLGGSVGGYITFAGGHRLIDG
                     GITGEENIKEITKSSLLGILVATMMRVLLFLAILAVVSKGLQLDPENPAASAFKFSAG
                     AIGYKFFGLVLWSAAITSVIGAAYTSVSFLKTLNPFIDKYEKYFIIAFIAISTLIMAF
                     IGKPATLLILAGALNGLILPITLGIMLIASKRKDIVGDYKHPTWLLIFGLIVVLISAY
                     TGITSLSSLGALFA"
     gene            10414..11109
                     /gene="pxpB"
                     /locus_tag="ACGI5H_002205"
     CDS             10414..11109
                     /gene="pxpB"
                     /locus_tag="ACGI5H_002205"
                     /EC_number="3.5.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889166.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0017168 - 5-oxoprolinase (ATP-hydrolyzing)
                     activity [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA];
                     GO_process: GO:0008152 - metabolic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="5-oxoprolinase subunit PxpB"
                     /protein_id="HFG9697908.1"
                     /translation="METRYLISGDKAVVAEFGNEISEDINKKVISFMRAIEISNLKGI
                     VTEMVPTYRSLMISYNPLEIDFDSLIENLKKIEDNLESIVLPKPKIHEIPVCYDEVFG
                     IDIKNVASYNNLTVDEVIKIHTSREYLIYMLGFTPGFPYLGGMDERIATPRLEVPRTK
                     IYGGSVGIAGSQTGVYPIDSPGGWQIIGRTPLKLYDENREEQILLRAGDFIKFVPITL
                     DEFIEIEKNNLSI"
     gene            11139..12125
                     /locus_tag="ACGI5H_002206"
     CDS             11139..12125
                     /locus_tag="ACGI5H_002206"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896290.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="biotin-dependent carboxyltransferase family
                     protein"
                     /protein_id="HFG9697909.1"
                     /translation="MGFKVELGGFQTLIQDRGRVGYGQYGVSGCGAMDEYAHRVGNIL
                     VGNSEDEASLEVLMLGPTITFDEYTQIAVTGGDLGAKINGKEIQNWRSYQINPGDVLS
                     FRGVKSGTRAYVSIAGGIDVPLAMGSKSTYTRAKIGGFEGRALKKGDYINTFIQEKDF
                     TINKKLSSKYIPTYSSEIVLRIVKGPQFDAFSNGEVEKFLSNKYKVTNEIDRMGCRLD
                     GESIKHLNGADIISEGISYGAIQVPGHGKPIIMLSDRQTSGGYTKIGNVISVDLYKLA
                     QAKPNDVVKFELVDIYEAHRLLREQEDKIQDIYKSMKNIRVVKAKVLNDIAV"
     gene            complement(12339..12905)
                     /locus_tag="ACGI5H_002207"
     CDS             complement(12339..12905)
                     /locus_tag="ACGI5H_002207"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428136.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="XRE family transcriptional regulator"
                     /protein_id="HFG9697910.1"
                     /translation="MLGEKMRNIRKSKKKTLSDVSKLTDLSISYISQIERDAIEPSLS
                     SLRKIAEVLDTPLYMFMDDNNTDDLVIRKEDRVMMKFPKSEMFYEIVSPMPTTEFTPS
                     ILFVEFELKPESEDAKDYIYHASEEIMVVTSGVVDICMGEKVVRLNPGDSTFIKANVP
                     HKIINPSKDTIARGYGVISPPIWPIKSK"
     gene            13257..14324
                     /locus_tag="ACGI5H_002208"
     CDS             13257..14324
                     /locus_tag="ACGI5H_002208"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902456.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mandelate racemase/muconate lactonizing enzyme
                     family protein"
                     /protein_id="HFG9697911.1"
                     /translation="MKITDIKFEKLRIKLKKPVVVSFGVIEYGESIILKIETDEGYCG
                     FGEAAPLAAVTGEVLDNVLSVLLMFKKELIGKDPLDIETIHTIMDGIIIGNTSAKAAI
                     DIALYDIKGKIMNAPLYKVLGGFDSKVQTDITISIDKPEKMAVEALERVKEGFRILKL
                     KAGINPEDDIEAVKLIREAVGESIRIRIDANQGWNVNSSINTIKKLEEFNVDAIEQAL
                     PHWDLDGTAYIRNKSNTKIMIDESLHSPIDAIKAIKKNAVDTFNIKLMKSSGIYPAIK
                     INNIAEASGVNCMLGCMLETRIGITAAANLIASKKNITEADLDSFMFCEELEGISGGF
                     VMDGDIMNLVNKPGLGIEVNL"
     gene            14343..15503
                     /locus_tag="ACGI5H_002209"
     CDS             14343..15503
                     /locus_tag="ACGI5H_002209"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419720.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF819 family protein"
                     /protein_id="HFG9697912.1"
                     /translation="MNTLFSNPGSILAVMTSMIALGFYLQRYKAIKSLGPALTIIIMG
                     IILSNLKVVPVSTELYGTISTYAIPVSMTIMLMSVDLKEMTKLSREPLIAIFVAVLTV
                     SIMAFLFGLVFAEKISEGWKVAGMFVGTYTGGSANLTAIGTGLNVSRQTLAAANAADY
                     VIGVPTLIFMFALPAILKNSKKFKKLWPYHVEESELEDCQNEEFMESKEWSIKDIAWM
                     LAIGFVVTEVATILAGYFNSSFSSAARILLVTTISIIIAQLKPVKKLKGNLDLGLFVA
                     LFFLCTIGFSVDIKEFLGSTFTITLYCFSIIFASFVFHLGITRLLKIKYQYVILSIVG
                     AIADGPTSALVAASAKWNSLVSVAVVMGVIGGVLGNYAGISVAYAIKMSLGL"
     gene            15516..17612
                     /locus_tag="ACGI5H_002210"
     CDS             15516..17612
                     /locus_tag="ACGI5H_002210"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896296.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CocE/NonD family hydrolase"
                     /protein_id="HFG9697913.1"
                     /translation="MIKFKLYISGLYSGNVIFDGDLLIEKLNPFTNKIESLKPISKEE
                     NTYYLNLTKIDLKSLFNNFDVYTKSLVNTDKDTVINNLGETHSKLNEYIWVQRNKKFP
                     LDIIIVDNKIVGFICLSRETCTILIMDGYEEYTVLKEWEKTHKNEEIYSIRFGGNYMI
                     DMKDGIKLSTDVYLPDFVDSTKKAPTILMRTPYGKENDKEIYYKYVQRGYAVVIQDVR
                     GRNESEGKWEPMIHEREDGDSTINWIVSQEWSSGIVGMLGASYLGYVQWAAASSGNKH
                     LKALVSIVTSGSPFIDIPRKGGAFVSGMLAWAFMVSRNKVDRSKMVRDDWDDVLNIRP
                     IENIPVEALGYRIEFLEEWLKRVEKDEYWDLMDWHLQKDKINVPALVVSGWYDDNSMG
                     TTEALDVIKDYEKGKRKAILGPWMHNSNTLRDINGISLGNSSLRYDLDYNYLLWFDKY
                     LKGIENNIDTTAPVEYYSVGSNKWKTEENWPIINKIDKSMYLISDGNANTSLGNGRLV
                     FDNGLEEKYDSYIYNPKDPSVQLIDMSENEVGVPNNYKDLEKRSDMLCYTSDAFSEEF
                     TVTGDIKLEFFASSSAKDTDWVIKIMDVDLDGNSIKLADGILSARFRNSFYKSEFMEE
                     GEIYKFTIITSKISNTFKVGHKIRLDITSSAKNFIFQNSNTTEGYNSIEYIEAKNTIY
                     HGGKYPSKLILPIENK"
     gene            complement(17771..18115)
                     /locus_tag="ACGI5H_002211"
     CDS             complement(17771..18115)
                     /locus_tag="ACGI5H_002211"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896298.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RidA family protein"
                     /protein_id="HFG9697914.1"
                     /translation="MEIKRYEGTGRMSRAVVHNNTVYLCGQTHAEGGVIEQTTEVLAK
                     IEDLLNKYGSDKQHLLSVTIYLRDMKDFEAMNSVWDAWVEKGFEPARACVEARLAREH
                     LLVEMSVVAATK"
     gene            18407..19297
                     /locus_tag="ACGI5H_002212"
     CDS             18407..19297
                     /locus_tag="ACGI5H_002212"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861195.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DMT family transporter"
                     /protein_id="HFG9697915.1"
                     /translation="MSSTIKSNRIKGIMFIIASALGFAMMSAFVKLAGDLPSFQKVFF
                     RNLVSAIIAFWLIIKHKGSLTGKKENLKVLLYRSIFGTLGVIFNYYAIDKLMLSDANM
                     LNKMSPFLVVIFCAIALKEKINVKQIGAIIIAFIGALFIIKPTFSVEIIPYLGGIAGA
                     VFAAMAYTCLRVLGDREDYYTIVFFFSVFSLVTVGPIAFAVYEPMTLMQLIYLLLGGV
                     FASLGQFGITLAYKYAPAKEISIFDYSNIIFSAILSIFLFNVYPDMLSVVGYLIVFSA
                     AFYMFLYNKKLDKLDKEKKK"
     gene            19515..20801
                     /locus_tag="ACGI5H_002213"
     CDS             19515..20801
                     /locus_tag="ACGI5H_002213"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438480.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="HFG9697916.1"
                     /translation="MEKVKVAVIGAGNRGTYAYAPYIYENSDVCEIVAVAEPKKGRRE
                     LFTQKYNLDSKNVFETLEDFFKHDKMADAVIIATNDDRHYDVAKLALEKGYHVLLEKP
                     MSNSLDGLVHIDDLCDKYKDKIFMICHVLRYSPFYNKLKEIVESKKLGELVSIQYNEN
                     IGYWHFAHSFTRGNWRNSNETSPLILAKSCHDMDILLYLVGSRCKKISAFGSLKHLNN
                     QNASGEMAQNCLQCLVEKKCPYSAKRIYLEKDRSINRAVHINPTEENLLNILKTSPYG
                     RCVYRCDNNVVDNMVNILQFENGVTATFNLCAFTKENGRTIKLMFSHGEVGGDLNKNE
                     IRIKEFGKNEEIVMNPSNQQNMVEEYDRNLIAEFIKLVSNKELEKGRVAAKEAIQSHV
                     MAFAAEYSRVSDEVVYIEEFFDSAKQMTKEIEETIF"
     gene            complement(20890..21333)
                     /locus_tag="ACGI5H_002214"
     CDS             complement(20890..21333)
                     /locus_tag="ACGI5H_002214"
                     /inference="COORDINATES: protein motif:HMM:NF025547.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="regulatory YrvL family protein"
                     /protein_id="HFG9697917.1"
                     /translation="MIKISNKRRIPLGEFISVFLFFAVFFGITFCIFTVIGIGFLSFL
                     GFEYKSLGAVLIFFLIYFCITTPIDFLCTTILDIFRYVNKLPYSIYKLCEFIIDFILT
                     FLAMNIIDTFMDSVTIPLSTEILFALLSYLLSECMDFFDRDKKKP"
     gene            complement(21357..22151)
                     /locus_tag="ACGI5H_002215"
     CDS             complement(21357..22151)
                     /locus_tag="ACGI5H_002215"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889182.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M55 family metallopeptidase"
                     /protein_id="HFG9697918.1"
                     /translation="MKLYLSADIEGTCGIVNWDETKLECEFSQHYRTQMSKEITAACD
                     GATQSGVHEILVKDAHDSGRNINPNILPENVKILRGWTKDPLVMMAGIDESFDACIFT
                     GYHSGATCNGNPLSHTMDIDYDYFKINDEIASEFTINAYIAAYYNVPVAFLSGDEMLC
                     ESAKKLNPNIVTVPVSKGIGNGSISIHPNLALKKIEKGVKKALSGDLSRHLIKLPDKF
                     KIEIKFREHYKAFKASFYPNMKKIDSQTVLFETEDYYEFLRMLLFI"
     gene            complement(22716..23192)
                     /locus_tag="ACGI5H_002216"
     CDS             complement(22716..23192)
                     /locus_tag="ACGI5H_002216"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419749.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SAM-dependent methyltransferase"
                     /protein_id="HFG9697919.1"
                     /translation="MKEILINPIGKICIQGEEVFIKLDKKYVPALNELDDFSHLNVFW
                     WADGFDNPELRSILETPKPYKSGPDVIGIFATRSPIRPNPIALTAVQIINIDHENGII
                     KIPYIDANDNSPVIDLKPYTPSVDRVENPSIPKWCSHWPKSVEKSGEFNWEDEIEF"
     gene            complement(23293..24462)
                     /locus_tag="ACGI5H_002217"
     CDS             complement(23293..24462)
                     /locus_tag="ACGI5H_002217"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902464.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M20 family metallopeptidase"
                     /protein_id="HFG9697920.1"
                     /translation="MLNIKTLCHEINDWVINIRRDLHKTPELGLEEFQTKKKIIKYLN
                     EIGINYIEYKNHTGITAYINVSPNFETVAIRADIDALPITEELNYSYKSINIGKMHAC
                     GHDAHTAILLGTCNILFKLKDYLNVNVKFFFQPAEETIGGAQLMIEDGCLENPNVKYI
                     FGLHVNSNINKNLIELKYNTLNASTDTLQLTVHGSKCHGAYPHQGIDAIVISAHIITA
                     LQTIVSRNTNPTDSVVISLGKIEGGIKENIVCDKVVIRGTLRTLTPETREFSKKRIRE
                     ICDFTCKTFGGSISVEIEEGYPALINSNHLVDYVKQNAVELFGEENIILKDSPTLGAE
                     DFSYFLRHCEGAFYHLGCANREKNITSPLHTSTFDIDEDCLITGVMLHVKNVLSF"
     gene            24625..25488
                     /locus_tag="ACGI5H_002218"
     CDS             24625..25488
                     /locus_tag="ACGI5H_002218"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419753.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LD-carboxypeptidase"
                     /protein_id="HFG9697921.1"
                     /translation="MLGIIAPSGPLRNTSLEEIKFNLESYGYEVKFSESCSLNYKGYL
                     AGNDDIRARDIEDMFLDKDVDIIMCLRGGYGTTRILDKINYDIIKQNPKPFIGFSDIT
                     GLNLAFYKNCGLLPYHGIMAANVGKWDKFTYKSLVNALEFKDELYLENPKEEKIYTVC
                     EGKAEGIIMGGNLSLIIATMGTKYEIDAKDKILFIEEIGEPQYKLDRMLTQLYSSGKL
                     EECNGIIFGDFKDCIEENDLMELLIEFANKVNKPSIYNLQSGHCIPMITIPLGRMCEL
                     DATEKIVKLKK"
     gene            25559..26152
                     /locus_tag="ACGI5H_002219"
     CDS             25559..26152
                     /locus_tag="ACGI5H_002219"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419758.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3867 domain-containing protein"
                     /protein_id="HFG9697922.1"
                     /translation="MSDDRIIDFNELKNKVKDSDVDKFEQYIYNLYFSVMDGKMSMAE
                     FSRKIFDYMRDNNISQEKFMKIQKQFMERYGMDTEEVEKQLRNFGIDPSTAGFMSNNT
                     SSKVSTEDLESFKKSAGFYEKYGEKIQPKSCITTFIKNDLNDINVIIDQEKIMLCSDR
                     KINLMDSELNEFLLEYKNMFNKKIKVVMCETTNKYDY"
     gene            complement(26403..27038)
                     /locus_tag="ACGI5H_002220"
     CDS             complement(26403..27038)
                     /locus_tag="ACGI5H_002220"
                     /EC_number="3.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861198.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="isochorismatase family cysteine hydrolase"
                     /protein_id="HFG9697923.1"
                     /translation="MDNLLNELEALKSNLDNLPIEKIENYDLSKTALFIIDVNNGFAR
                     QGALYSPRVESLIKPIEMFTKKISNKLNRVIAFTDSHTPKSIELLSYPVHCLENDVES
                     ELVDELKSIENLQILPKNSTNGFFALENLDFDNIDNIIIVGDCTDICIYQFAITLKSY
                     FNQHNIEKNIVVPMNLVDTYDIPNVHPAEILNLVFFNSMIQNGVNVLKEIR"
     gene            complement(27118..27849)
                     /locus_tag="ACGI5H_002221"
     CDS             complement(27118..27849)
                     /locus_tag="ACGI5H_002221"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861199.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerophosphodiester phosphodiesterase"
                     /protein_id="HFG9697924.1"
                     /translation="MNIYAHRGFSGKYPENTILAFKKCLDMDIYGIELDVHRTKDGKI
                     VVIHDEKVDRTFNGHGFVKDFTLRKLKTLNSSFEGYQSNKECKIPTLEEVLILISPTD
                     LTLNIELKTDKINYPNIEKGVLELILKYNMKNRVLISSFNSNSLKNFHKLDPSVKTGL
                     LCYLPINNVVNFAKFLGNSYLHPPLVLVNESLIELCHKNLLGVNVYTVNEEDDILHCL
                     KLNVDGIFTNYPDIASNLLHSKQYS"
     gene            28180..30369
                     /locus_tag="ACGI5H_002222"
     CDS             28180..30369
                     /locus_tag="ACGI5H_002222"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419766.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid adenylation domain-containing
                     protein"
                     /protein_id="HFG9697925.1"
                     /translation="MYEVNLERAMNYWMDLLDDYTNIAKIPNDFFYKDCSDEVVDEVF
                     KMNIEKHERLIQYSKVNNISIDSIIETIYGLILQKYIYEDDVVFGKTMNIIPIRVRVR
                     QSEKFIDVVRKLKRQWSRSLEYGYYLLSDIENKNHLNTKLINTIFIAKSFDLSYDYDI
                     EKKGYDLSVIVYTKRALKIKIKYKPSIYKRETIRRILNQFDYIIEQIIEDNDILIEDL
                     EFVCKEEEKVLLEDFNNNQYEVPYDKSYVDLFREQVKVTPSNIAARDENRKLTYKELD
                     EVTDKLAGYLNHIGVESEDIVAVMLPRDINIIITAIGIMKSGGAFFPIDTSNPEERLN
                     YLLEDSNAKVVITTDELKSKVVNENTIVLDINDEEMFKFGYELTEKITSSNCAYTIST
                     SGSTGRPKTIAIEHKSLVNMCYYSVKSISATENDICGIYLSFSFDAVMKQLFPYLLVG
                     ASIDIMPEEAKFDEYTVNEYCEENDITILALPTAFARLFIQNCNNNSLRVVQTGGERL
                     KGYRKRNYELYNEYGPTEFTVVSTSFHVDREYGKIPIGKPIFNTYAYVLDKKNKLCPI
                     GAPGELCLSGIQISRGYLNKKGLTEQVFVENPYKTCEHNKLMYRTGDLVRWLDDGNLD
                     YIGRMDNQVKIDEFRIELYEIENIINNITEIKSVVCISRTNDDGDIYICAYYVIDEED
                     SGKINERTIREYLNEHLPPYMIPTIIMRIDKIPVTPIGKVNKRALPE"
BASE COUNT        11442 a         3616 c         4941 g        10537 t
ORIGIN      
        1 gcaacataaa aattatttat ctattttctc atctttattt ttgttatact caatttttcc
       61 taaatccttc tctttttcat attcatgaag ttttaattca atcatacctt ctattttggc
      121 tttatcataa tcatttaact ttctaaaatt gtttaaaagc tttatttcat tagagtttat
      181 gctattaagt ggatagtttg aggaggaatc gcaaattaaa tctgatttat gtgatagatt
      241 atctccattt aatagccagt ctactgaaac attaaatatc tcagctatag attttaatat
      301 ttcataattt ggttttctaa tgtttctctc aaatttactt aagttgtcac agcccaacat
      361 ttcttctagt tcatattgtt taaggttttt tgcttttctc aaataaacaa ttctttctcc
      421 taaagtatcc ataaacactc tccattcaat taatgtcaaa aagacttttt aagatgtaaa
      481 tagtttcaaa tttaaggtca aaatgacata aaaagcattg acttaaggtc aaaatgactt
      541 tataattaac ttaatgatac gaatttacat cctaatttta gcacaaagta atcaaaaaat
      601 cttatttagt attaaataaa tttatatact taatatgtgt acatattaaa aatatatact
      661 aaatagaggg ggtgtgtaag ctaaaataat ataaaagtaa atataaatca cttagaaagg
      721 aagttgataa atggatgctc gaaaaaaatg gatacctttt ttgggagtgc aagtcaagca
      781 aagacttatt gaattaaata tgactcaaag ggaattagcg aagaaaatag gtgttaatga
      841 aaactatttg tcagctattt taaatggaag aagaacaggt aaaaaatata aatcatcaat
      901 ttatcaatta cttaatatag aatattcaga agatgattaa taaatagtat ataaagtagg
      961 tgaatattct tgtgtgtaaa ttggattcag atggggttat agagtgttgt agagcaattg
     1021 atgattttat tacagcactc agtaatataa aaagcttaaa tatggaaaga ttaaatactt
     1081 taactaaata ttctagtaca tgttcaatcc ttcttaaaga ggggaattat gaaggatgta
     1141 caattgtgta tagaaagatg ttggaagaat taaaaacatg agtaatgcat ttcttaggaa
     1201 tataagttat acatagagat gtattatatt tttcaaagta cttaaactaa aatatggata
     1261 agataatcta aatattataa atgtgcttga aattagacta tacttgtttt taaataatcc
     1321 aatatccata ttttagtaat atactacaaa aaaagaaggt taatagatga tgtaaaatcg
     1381 tatcaaatta tgtatgttta aaccatttta tcttcattat tattagagga atgctttttt
     1441 aagtctttat attcagatat cttaagttca agtattcctt ctatttttat tttatcacgt
     1501 tcgtttagtt gtctgtatag atttaatatc gtcatttcat cattagtaac atgtaagtaa
     1561 tcttctttat cttcttttac actactattg acatttacct tctctttacc atagagaagc
     1621 cagtcagtcg taacattaaa ataatcagct attgacatta gtatatcaca attaggtttt
     1681 ctatctcctg tttcatactt gcctaagttt tcaaatttta aaatatccat aagtttgcgc
     1741 tgagtaagtt ttttggagtt tctcaaataa gcaattcttt ttcctaaagt atccacaaaa
     1801 tacactcctt tctttttatg agtaatgtct aaatgacatt taaaattaaa aatatataaa
     1861 tttataatat aaaactacta aattaaagtc taaatgacat tttgcttaaa ttaatatgct
     1921 cataatatga ttttaacata ttatagttga aaatatatgg tttattttga tttgtatata
     1981 taacaatagg tttaattgtt atataaatgt aaaggggtgt atgaatagat tgtataaatt
     2041 tatttcgata aactaagatt gctttttgat tgtctgtaaa agagaaaaag attaagagaa
     2101 aaatagtatt atattgtaat ttatattaat caattacaaa aattttatga atttattctt
     2161 tagaataaaa tatttaagaa taagataaat ttacaatata atactataac actcttttat
     2221 ctagttttat tttctttata gaacaataat attataaatg ctagtagatt tacacagaat
     2281 actgttatat acatctgttt aaatcctgag tttagagtag attgtagtgt gttttctatt
     2341 tttgttctat tattttctat ggaatttata taatccaatt ttgatttatc aaaagccttt
     2401 ggtatttcag tttttacctc ttgtgtcttt gctaaaactg cttggagtga ttttttttgc
     2461 tgttgcattg tatcaaggct tttttccatg tctttctttt ggcttataga attatttaac
     2521 ttgctttgta gctctttctt ttgagattcc attgttctta gttttttact taattcgttc
     2581 ttttgagttt tatttttttg taactttgta tttaagtcat ctcttgtctt ttttagttgc
     2641 tgtatttgag catttaaact ttctttttgt tcatttacat ttggtttatt ctcgctggaa
     2701 ttgttattct tattttctgt agaatcattc ttagtgtcgt ctgattcaga attactggta
     2761 ttactctggt tttgttcatt tgagttattt tcgttatcag taggagtttt ttctgtagta
     2821 ggtattttat tataagcagt tgtaagttcc ttgatggcct catcttgttt ttcaagacct
     2881 tgttccatac cttttatacc tttatcaaca ccagcaatac ctttttttac accatctatt
     2941 ccttgattaa taccagctct agcttttacc atattgtcaa taccagtttg aactccttta
     3001 ataccactat ttagtttatt ttcaccatct tcaataccgt ttattccact ttgtgttcca
     3061 tctattcctt tttgtacatt tttctgtatt ttagtaatta tagatggaac tttttcatca
     3121 aacattgttg ttgatatttc ttttgttata ttggtaatgt tggttgtatc tgctgactga
     3181 actttattaa gtaaggattt tggaagtttg ccacctgtca tgtccatatt tatatttgaa
     3241 gtatcattca tatttgggat agagacattt tttaaatttt ttgccatttc agggtctgat
     3301 tttaagtcat ctatcatgtt ttcaagttct tcaagttgaa ctattttagg agttgagggc
     3361 tttccaacta agtccataat attatcttgc acagataatc ctgcatgtgc tataaatcca
     3421 atcattatag ctggagaaat tgaagtacca attgagcgta tcaaggataa tgttgcaagt
     3481 gctgaattag attcttctaa tcttgtattt gataacatca tatagtttag aggagttccc
     3541 atagtaaatc ccattcctaa tcccataaat attaaactta cacatacact aaatacagta
     3601 ttggttttta gagcaattaa aactaggtaa agagagccta tcatagatac agaaaatcct
     3661 agtaatagta ttttttttgc cccaaacttg tcaataagtc ttccgcttaa aggagcagca
     3721 atacctgcaa ataatcccaa tatagctaca aaatatcccc cagaaccagc atttatcttt
     3781 aatgcatttt cagcatactg tggaacgaat accataccca tcattccaat accaacaatt
     3841 aaagataaaa taagtactat caatattctc ggatttaaaa aatattcaaa gcttaaaata
     3901 gggtctttag ctctattttc aataaatatg aaaataggta taagtacaat aaatgtcaat
     3961 aagtatggat aaactgatat atcttgtata gaatttttaa aattaaaaaa gtctatattc
     4021 ataagaccat ataatagtga tacgattata catatcaaca tcaatgtacc aagcttatct
     4081 attttttctt tagattcaga cttattgttt ttaatacaga aaactccacc aataagtatg
     4141 attaaacaaa ttggaagatt tacaaaaaat agccacttcc aattttgagt tccaaagata
     4201 cttagaattg tgctaccaat gcttgaacct aaaatattgg caataccata tgttgcccca
     4261 actaaaccta aagccatgcc tcttttattt tctgggaagg tagttccaaa ttctgctgta
     4321 gcaattggca tgattccacc accaccaatt gcttgaataa cacgaccaat taataaaata
     4381 tagaaattgg aaaatagtga tgataatcca catattaatg aaccactacc aaatagaaat
     4441 atactaacta gatacacata ttttcttcct attttatctg ctaattttcc agagatagga
     4501 attacagaag cgtatgttaa tgtgtatatg gtaatcatcc aaattcccgt tttttcattt
     4561 actccaaggc tattttgtat aatcgttctt gctggtgata ctattccagt atcaatagct
     4621 cccataaata tacctaatag ataaagcgta agtactaaaa atatttttgg attactgtcc
     4681 ttgttcttaa tactagtatt atgattcaag gtaaacacca ccttaatgta ttaatttttc
     4741 aatatagggt tttaaatctt caaattctat atgaagatat gttgaatatg aaaaaaacat
     4801 ttttattatg atattgcata ctaatttgtc attattaaaa aaactttctt tttctaaagc
     4861 ttcatatact ttatttgaaa gctgttcatg aaagtcgtct ttgtgttttt tcatttcaaa
     4921 aaatctctct gtttcaaaag tgtttaaaaa gtcattgtat tggatattat gaactttgtt
     4981 tataaaattt cttatttcag taaaaataat gtttagtttt tttatgtaat cttcagtgtt
     5041 tttattggag tattcaattc gccttatcaa taaatcccat tcagattttg tgatatattc
     5101 tattatttct tgttttgaat taaagtaatt atacactgta cctgcactta taccacacct
     5161 ttgagctatt ttccttatgc taatattcga gtaatcttct tctaaaatca tatcccgaga
     5221 cacttttaat atatcttctt ttacattttc taaaatcttt ggcatattac cacctctttt
     5281 attaaaatta ttatgaacac tgtttattat actcctttaa aatttattaa tcaatatgta
     5341 agctataatg tataatatta ttatatagat atgatagaaa ataagtgtct tcttactaaa
     5401 tatctattat attaaatttg tacttaagta tgattattta ttgaaatatg tgatattaaa
     5461 tttttctttt taataaatta aatattatat gataaggaga atatggtgat ggaaaagaag
     5521 tatgtaatgg cattagacca aggaacaacc agttcaagag ctatactatt taataaaaaa
     5581 ggcgaaatag tgaaaattgc acaaaaagag ttcaatcaaa tttatccaaa agctggatgg
     5641 gtagagcatg accctatgga aatatggggg tcacaaagtg gggtaatgag agaagttata
     5701 gaaacagcag gtataagacc agaagaaatt gcttcaatag ggataactaa tcaaagagag
     5761 actacggttg tttggagtag gtatactggt aaacctattt ataacgcaat agtatggcag
     5821 tgtaggagaa cgtcagaaat atgtgatgaa cttaaaaata aaggattgga agaatcaata
     5881 aaagaaaaaa caggtctttt aatagatgca tacttttcag caacaaaagt aaaatggata
     5941 ttagataatg tagaaggagc tagggaaaaa gcagaacaag gagagttatt atttggaact
     6001 atagatacat ggttaatatg gaatttaact cgtggaaaag tacatgtaac agattactca
     6061 aatgcatcta gaacaatgat gtacaatata aatgatttag aatgggatga ggatatatta
     6121 cgagaattgg acataccaat aagcatgttg ccattagtaa aaccttctag ctatgtttat
     6181 ggtcatacag atgagcgcat gttatcagga gctaaaatac ctattgcggg atgtgctgga
     6241 gaccaacaag cagcattatt tggtcaaaat tgtgttgaag aaggtactgc aaaaaatact
     6301 tatggaacgg gttgtttctt gcttatgaat acaggcagta acatagttaa atctaagcat
     6361 gggttactta caacaattgc ttggggagtt gatggaaaag taacatatgc attagaagga
     6421 agtatattta ttggaggagc atctgttcaa tggcttagag atgaattaaa gataattgaa
     6481 tctgcaaaag atagtgaaat gtatgcaaat agggtagagg atactaatgg tgtatatgta
     6541 gtgccagcat ttacaggtct tggagctcca tattgggata tgtatgctag gggttcaatt
     6601 ttaggactta caagaggagc aaaaaaagaa catatagtaa gagccacatt ggaatcaatt
     6661 gcttatcaga caaaggatgt tttagaagca atgcaaaacg attcaaaatt aaaactaaaa
     6721 tcattaaaag ttgatggtgg agcaagtaat aataattttt taatgcaatt tcaatcagat
     6781 atattaaatg tagatataga tagacccaaa atagtagaaa ctacagcttt aggagctgct
     6841 tatttagcag ggttgtctgt tggattctat attggaagaa atgaaattac ttcaaagtgg
     6901 tcagtagaaa aagagtttaa tccaaatatg agtgaagaga agagatgtaa attatataaa
     6961 ggatggaaaa aagctgtatc gagagcttta agctgggaaa aagaagatga attggatatt
     7021 taaaaattaa tcaaagttaa atttatttga atttaaaaag agctttatgt aaaatatgaa
     7081 gctctttttt tgttgttaat cttgcatttt tatataatca cactaaatta tataatttat
     7141 ttttcgtttt catataaaaa cattggtata gaattgtaaa tgtgttggtc accaactact
     7201 aagagaatgt ctccttctaa aaattcaata tatggtccag gagatattat aagttcttca
     7261 cctcttttaa ttgcaactat tgtagcacct gtattttgcc aaaatttagt ttgtgcagct
     7321 gtttgaccaa tatatttgca attagaattt atggtgaact gaacgggcac taaaggattg
     7381 attatttcaa gtctgttaga atagtctaaa attttattta tagtatctaa tatttcattt
     7441 tctaaattag atttagtatc tattaaatta taaagtgttg atttatatga tgatatattt
     7501 gtaatatctc tatatttttt tataaaagaa gaagctttgt ctggagatag tacaataaca
     7561 cctttaccct ttatgctttt aacaacgcca atgtcctcta aaattttgac agctcttctt
     7621 atcgtttctg gagatacatt gtatttacca gccaaaacag agcgtccaaa tagtactgaa
     7681 tcctcttgta tttcacccgt gtatatttta tttgcaatat ccaacgctat tttttggtat
     7741 attggcatcg tatagttttt atccattgtt tttcccccaa tacaaaattt atgttaaaaa
     7801 aatatataat cttaacaata ctattgtata atttataggt ttatatgtct acaatatgta
     7861 caaatattgt gcatgtttta aaataatatt ttaacatgca tttagtatac atgattttat
     7921 tatacttaaa actatataaa gaattaatta taaaaatata aagatatttt acttacaaag
     7981 aatgataatt atatagatga aagaaacaaa tgaatgaaga aaaatgattc tgtcttgcat
     8041 ataaagtgat taaaaatgaa aaatacttta aaaatgaagg ttaaagccct tattttaagt
     8101 gaaaataatt aattattaac taaaaaatgg taaaaagatt ttttgaaaaa gaaatacaaa
     8161 tgaatgttca attaaaataa ttgcaaaaat attccttaaa tggtaaaatt atattaatta
     8221 aatgcaatag aatagttgca aaaataaaat tgaatacaag tgataaaata tttcatgcaa
     8281 tatataaaat aaacaaaatt taaaaattaa aactacttat tctatcaaaa tgttagcgag
     8341 gaggggtcat aaattgtata aagtagattt aaatagtgat ttaggagaaa gttttggaac
     8401 gtataagatt ggtttagatg aagaagtttt aaaatatatt tcatcagcca atatagcttg
     8461 tgggtttcat gcaggtgacc ctagtcatat ggaaaaaaca gtacagctag ctaaaaaaaa
     8521 tggagtgaaa ataggcgcac atccaggttt cctagattta ataggatttg gaagacgtga
     8581 gatgaaaata acaaagcagg aagctaaaga ttatacaaaa tatcaactgg gtgctttaat
     8641 ggcatttgca agttcaaatg gatgtaatat acaacatgta aaaccacatg gagcattata
     8701 caatatggca gctaaagata aagagttagc tatggggatt tgtgaagcta tatatgaagt
     8761 cgataaagat attatactgt tggggctata taatagtgaa atgataaatt ctgctaaaga
     8821 aattggactt aggtttgcaa atgaagtatt tgcagataga gcttatgata ataatggttt
     8881 tttggttcca agaaatgtag aaggagcagt tatacatgat acaaaacatg caatagatag
     8941 ggttgttagg atggtaaaag aaggaactgt agaaacttta acaggtgaag ttatacatat
     9001 caaagcagat tctatatgtg tacatgggga caatccaaaa gcaatagagt ttgtcaaaga
     9061 aataagaaag cgttttgaat tagaaggtat agaagtttgt ccattagaaa acatagaagt
     9121 ttgttcgtca gagaacatag tataagactg ataacatgag ggggagataa aatatgagta
     9181 caaaaaatat tacagataaa actaaaaata aaaaagatgt cggagcactt ataggggctg
     9241 catttataat ggcaacatca gcaattggac cagggttttt aactcagact gcacaattta
     9301 cccaagattt tggaccgaat ttttcatttg taattttaat tacaacaatc ctttttatag
     9361 gggctcaagt aaatgtatgg agagtaattg gtgtatcagg acttagaggt caggatatag
     9421 caaataaaat aatacctgga ttaggctatt tagtagcttt tttagtagct cttggaggat
     9481 tagcttttaa tataggaaat gttggtggag ctgcacttgg tatgaatgta atgtttaata
     9541 tgaatatgac attaggaact gtattaagtg gattaatagc tatatttgta tttatgtcaa
     9601 aaaattcaaa ttctctagtc gataagataa ctaaattttt agcattagga atgataatta
     9661 tagttggata tgtagcaata tcaaatcatc ctcctgttgg agaggcagta tcaagaatgg
     9721 taaaaccaga aaatccaaaa ggactgatat tcccaataat aactttactt ggaggaagtg
     9781 ttggaggtta tataactttt gctggaggac atagattaat agacggtgga ataacaggag
     9841 aagaaaatat aaaagaaata actaaatctt ctcttttggg tatattagtt gccacaatga
     9901 tgagagttct tttattttta gcaatactgg cagtggtttc aaaaggtctt caacttgacc
     9961 cagaaaatcc agcagcttca gcttttaaat ttagtgcagg agcaatagga tataaattct
    10021 ttggacttgt attatggtct gctgcaatta catcagttat aggagctgct tatacatcag
    10081 tttctttctt aaagacacta aatcctttta tagataaata tgaaaaatat tttataatag
    10141 catttatagc aatatcaaca cttataatgg catttatagg aaaaccagct actttattaa
    10201 ttttagcagg agctttaaat ggattgatac ttccaatcac attaggaatt atgcttatag
    10261 catctaaaag aaaagatatt gttggagatt acaagcatcc tacatggctt ttaatatttg
    10321 gattaatagt agttttaata tctgcatata caggaataac ttctcttagc agcctaggtg
    10381 ctttatttgc ttaatttaga agaggtgaca tttatggaaa ctagatactt gatatcaggg
    10441 gataaggcag tggttgctga atttggaaat gagatatcag aagatataaa caaaaaagta
    10501 atttcattta tgagagcaat agaaatatcg aatcttaaag gtattgtaac agaaatggta
    10561 ccaacatata ggtcacttat gataagttat aatccattag aaatagattt tgatagtttg
    10621 attgagaatt taaaaaaaat agaagataat ttggaaagta tagtattacc aaaacctaaa
    10681 atacatgaga ttccagtatg ttatgatgag gtttttggta tagatattaa aaacgttgca
    10741 agctacaata atctcactgt agatgaagtt ataaaaatac acacaagcag agagtacttg
    10801 atatatatgc tagggtttac tcctggattt ccatatctag gtggtatgga tgaaagaata
    10861 gctacaccta gattagaagt gccaagaact aaaatttatg gtgggagtgt tggaatagca
    10921 ggttcccaga ctggtgtata tcctattgat agtcctggtg gatggcaaat aattggtagg
    10981 acacctttaa aattatatga tgaaaataga gaagaacaga ttttgcttag agctggagac
    11041 tttataaaat ttgttccaat aacattagat gaatttatag aaatcgaaaa aaataactta
    11101 agtatttaaa tatcgttata gtacagggag tggtatatat gggattcaaa gttgaattag
    11161 gaggtttcca aacattaata caagacagag gtagagttgg ctatggtcaa tatggtgtat
    11221 ctggatgtgg agcaatggat gagtatgcac atagagtagg aaatatatta gtaggaaatt
    11281 ctgaagatga ggcttcttta gaagttttaa tgttaggtcc tacaattacc tttgatgaat
    11341 atacgcaaat agcagtaact gggggagatt taggggctaa aataaatgga aaagaaattc
    11401 aaaactggag gtcatatcaa ataaatccag gtgatgtatt atcatttaga ggtgtgaaat
    11461 caggtactag agcctatgtg tcaatagctg gtggaataga tgttccactt gcaatgggaa
    11521 gtaagtcaac ttatacaaga gctaaaattg gtggatttga aggtagagca cttaaaaaag
    11581 gcgattatat aaatactttt attcaggaaa aagattttac aataaataaa aaattaagtt
    11641 caaaatatat tccaacttat agttcagaaa tcgtactaag aattgtaaaa ggtcctcaat
    11701 ttgatgcttt ttctaacggt gaagtagaga aatttttatc aaataaatac aaagttacga
    11761 atgaaataga tagaatgggt tgtagactag atggagagag tataaagcac cttaatggag
    11821 cagatattat atctgagggt atttcttatg gagctataca agtacctggt catggaaaac
    11881 ctattataat gttatcagat agacagacta gtggtggcta tactaagata gggaacgtta
    11941 taagtgtaga tttgtataag ttagcacaag caaagccaaa tgatgtagta aaatttgaac
    12001 ttgtagatat atatgaagca catagactat tgagagagca agaagataag attcaagata
    12061 tctacaagag tatgaaaaat ataagagttg taaaggcaaa agtattaaat gatatagcag
    12121 tttaatttta acaaatacaa tttttattat agtttataat ataacttaca aatagctatt
    12181 tactatttac cataattaag atggtttaga ttagtcaaat agctattttt ttagtttgag
    12241 taaatatttt aaatttaaat aaatacttca attttaaaat aaaagcaata tttaaatcta
    12301 ttatattatc tacaaaaagt aggtgtgtca tattgagttt atttagattt tattggccaa
    12361 attggaggtg atataactcc atatccacga gctattgtat ctttacttgg attgatgatt
    12421 ttatgtggta cattagcttt tataaatgtt gagtcacctg gatttaatct aactaccttt
    12481 tcacccatac aaatatcaac cacaccactc gttaccacca taatttcttc tgatgcatga
    12541 tatatataat ctttggcatc ctcactttct ggtttaagtt caaactctac aaataaaatt
    12601 gaaggtgtaa actcagttgt aggcattgga gatactatct cgtaaaacat ttcactcttt
    12661 ggaaatttca tcataactct atcttctttt ctaatgacta aatcatcagt attattgtca
    12721 tccataaaca tatataaagg agtgtctaaa acttcagcga tttttctcaa tgaagacaag
    12781 gatggttcaa tagcatctct ttctatttga gagatataac ttatagataa atctgtcaat
    12841 ttggaaacat cacttaatgt ttttttcttg ctttttctta tatttctcat cttttcacct
    12901 agcataagaa cctccaaata ataaaattaa tataaaatat tcgcttaaaa caaagtaatt
    12961 atagcacaac atagaagtag tggcaataag aatacatagt agattttgac aattaaaatt
    13021 taattaaatc caaataaaag tctatgaaaa tgaattattg ttaaattaat acaaagaaaa
    13081 taataataaa aaaatttaat agaagagtat taattgaatt aagattatca cattatattt
    13141 tggaaaagag taaattttca gtaaattatc ttgacatata tattgaagta ataatataat
    13201 ttaaagtata aaattttaaa aattgaatta taacttcaaa aaataaggag ggtaatatga
    13261 agataacaga tatcaaattt gaaaagctta gaattaaatt aaaaaaacct gtagtagttt
    13321 catttggagt aattgaatat ggagaaagta taattttaaa aattgaaact gatgaagggt
    13381 attgtggatt tggcgaagca gcgcctcttg cagcagttac aggtgaagtt ttggataatg
    13441 ttctttcagt attgcttatg tttaaaaaag agttaatagg caaagaccca ctagatattg
    13501 aaaccataca tacaatcatg gatggaatta ttataggtaa tacttctgca aaagcagcta
    13561 ttgacatagc tttatatgat attaaaggaa aaattatgaa tgcacccctt tataaagttc
    13621 ttggaggatt tgatagtaaa gtccaaacgg atattactat aagtatagat aagccagaaa
    13681 aaatggcagt agaagcttta gaaagagtaa aagaaggttt taggatattg aagcttaaag
    13741 caggtataaa tcctgaagac gatattgaag ctgtaaagtt aattagagaa gccgttggag
    13801 agagtataag aattagaatt gatgcaaatc aaggatggaa cgtaaatagc agtataaata
    13861 ctatcaaaaa gttagaagaa tttaatgttg atgcaattga acaagcactt ccacattggg
    13921 atttagatgg tactgcttac ataagaaata aaagtaatac aaaaattatg atagatgaat
    13981 cattacattc accaatagat gcaattaagg ctataaaaaa gaatgcagtt gatacattta
    14041 atattaagct gatgaaatca agtggaatat atcctgctat aaaaatcaac aacatagctg
    14101 aggcaagtgg agtaaattgt atgttaggat gtatgctgga aacgagaatt ggtataacag
    14161 cagcagcaaa tttaatagca tctaaaaaga acataacaga agctgacctt gatagtttta
    14221 tgttttgtga agaattagaa ggtatatctg gaggatttgt aatggatgga gatattatga
    14281 atcttgtcaa taaaccaggt ttaggaatag aagtaaactt atgataaatt tggaggttaa
    14341 atatgaatac acttttttca aatccaggta gtatacttgc tgtaatgaca tcaatgattg
    14401 cattgggttt ttacttacaa agatacaaag ccattaaaag cttaggacca gcacttacaa
    14461 taatcataat gggaataata ctttcaaact taaaagtagt tccagtaagt actgagttat
    14521 atggaactat ttcaacatat gctattccag tttctatgac tataatgttg atgagtgttg
    14581 acttaaaaga aatgacaaaa ttatcaagag aacctttaat tgcaattttt gtagctgtat
    14641 taactgtaag tatcatggca tttttatttg gattagtatt tgcagaaaaa atatcagaag
    14701 gttggaaggt tgctggaatg tttgtaggta catatactgg tggaagtgct aatcttacag
    14761 ctattggaac aggtcttaat gtaagtagac aaactcttgc tgcagcaaat gcagcagact
    14821 atgtaattgg agtaccaaca ttgatattta tgtttgctct accagcaata ttaaaaaatt
    14881 caaagaagtt taaaaaactt tggccatatc atgtagaaga atcagaatta gaggattgtc
    14941 aaaatgaaga atttatggag tcaaaagaat ggagtattaa agatatagct tggatgttgg
    15001 ctataggttt tgttgttaca gaagttgcaa caatacttgc tggatatttc aattcgagtt
    15061 ttagtagtgc agcaagaata cttttagtta caacaatttc aattataatt gctcaattaa
    15121 agccagtaaa gaaactaaag ggaaatttag atttaggatt atttgttgca ttattctttt
    15181 tatgtacaat aggtttttca gtagatataa aagaattttt aggttcaact tttactataa
    15241 cactttactg ttttagcata atttttgctt catttgtttt ccatttaggc ataactagac
    15301 ttttaaagat aaagtatcaa tatgtaatac tttctatagt aggagcaatt gctgatggtc
    15361 ctacttcagc tttagtagct gcttctgcaa agtggaattc gcttgtaagt gtagcagtcg
    15421 taatgggagt aattggtgga gtattaggaa attatgcagg tatatcagtg gcatatgcaa
    15481 taaagatgtc tctaggatta taggggggag tttaattgat aaaatttaaa ttatacatat
    15541 ctggactata cagtggaaat gtaatctttg atggagattt attaattgaa aagttgaatc
    15601 cttttacaaa taaaatagaa agtttaaaac caataagcaa ggaagaaaat acatactatt
    15661 taaatcttac aaaaatagat ttaaagtctt tatttaataa ttttgatgta tatactaaaa
    15721 gcttagtaaa cacagataaa gacacagtta taaataactt aggagaaacg cattctaaac
    15781 ttaatgaata tatatgggtt caaagaaaca aaaagttccc actagatata attattgtag
    15841 ataataaaat agtaggtttt atctgtttat ccagagaaac ttgtactata ttaattatgg
    15901 atggatatga agagtatact gtattaaaag aatgggaaaa aactcataaa aatgaagaga
    15961 tatattctat aagatttggt ggaaattata tgattgatat gaaagatggt ataaaacttt
    16021 ctacagatgt atatctccct gattttgtag attctaccaa aaaagcaccg acaattctta
    16081 tgagaactcc atatggaaaa gaaaatgata aagaaatata ttataaatat gtacaaagag
    16141 gatatgctgt tgtaatacaa gatgttaggg gaagaaatga atcagaaggt aagtgggaac
    16201 ctatgattca tgagagggaa gatggagata gtaccataaa ttggatagta tcacaggaat
    16261 ggtcaagtgg aatagttgga atgcttggag catcatatct tggttatgtc caatgggcag
    16321 ctgcatcttc aggcaataag catcttaaag ctttagttag tatagtaaca tcaggaagcc
    16381 cttttattga tataccaaga aaaggaggag cttttgtatc tggtatgctt gcatgggcat
    16441 ttatggtatc aagaaataaa gttgatagaa gcaaaatggt aagagatgat tgggatgatg
    16501 ttttaaacat acgaccaata gaaaatatac ctgttgaagc tcttggatat agaattgaat
    16561 ttctggaaga atggttaaag agagtagaaa aagatgagta ttgggatttg atggattggc
    16621 atttacaaaa agataaaata aatgtacctg cattggttgt atctgggtgg tatgatgata
    16681 atagtatggg aactacagag gccttagatg ttataaagga ctatgaaaaa ggaaagagaa
    16741 aggctattct aggtccatgg atgcataatt caaatacttt aagagatata aatggtattt
    16801 ctttaggaaa tagttcatta agatatgatt tggattataa ttatctatta tggtttgata
    16861 aatacttaaa aggtatagaa aataacatag atacgactgc tccagtagag tattactctg
    16921 taggttctaa taagtggaag acagaagaaa attggccaat aataaataag atagataaaa
    16981 gtatgtatct aataagtgat ggaaatgcta acacatcttt aggaaatggt agattagtat
    17041 ttgataatgg tttagaagaa aagtatgata gttatatata taatccaaaa gacccatcag
    17101 tacaactaat tgatatgtca gagaatgaag ttggagttcc aaataactac aaagatttag
    17161 aaaaaagaag tgatatgttg tgttatacat cagatgcttt tagtgaagaa tttactgtaa
    17221 caggtgatat aaagttagag ttttttgcat caagttctgc caaagatact gactgggtta
    17281 taaaaattat ggacgtggat ttagatggaa attcaattaa attagctgat ggtatactta
    17341 gtgctagatt tagaaatagt ttttataagt cagagtttat ggaagaagga gagatttata
    17401 agtttacgat tataacttca aaaatatcaa acacgtttaa agttggtcat aaaattagac
    17461 tagatataac gtctagtgct aaaaacttta ttttccaaaa tagcaacacg acagagggat
    17521 ataatagtat tgaatatata gaagcaaaga atacgattta tcatggaggt aaatatccat
    17581 ctaaattgat attgccaata gagaataagt aaatttatat agattaaata gtgaggaggt
    17641 gtctcaaaat gaatttttta gttcgtgaga cactttcttt tatacaaaat caaatgtatt
    17701 ttcatcattt caacaatgaa aaagaggctt atctctctgt tttgagatag cctcctataa
    17761 gctaaattga ttattttgta gctgcaacaa cgctcatttc aactaacaaa tgctctctag
    17821 caagtctagc ttcaacacaa gctctagcag gttcaaatcc tttttcaacc caagcatccc
    17881 aaacagagtt catagcttca aagtctttca tatctcttaa ataaatagta acagatagca
    17941 aatgttgctt atctgaacca tatttgttta ataaatcttc tattttagct aaaacttcag
    18001 ttgtttgttc aattactcct ccttcagcat gagtttgtcc acataaataa actgtattgt
    18061 tatgaactac agctctactc attcttccag ttccttcata tctctttatt tccatatttt
    18121 aaatacctcc atagttaaaa aatctattaa aaatctaaat aataaattaa aaaaagtcta
    18181 tactatataa aattatatta tatattctga taataatcca taaaaacata taacttttta
    18241 gctataatta ttattgttat taattgaaaa gatttattag ttacttgaca tagtttacac
    18301 ttttaattat agtataaatt ggaatattta gataattatt atttaatgta taagctaagt
    18361 ttttaattaa tatggtttta tacatttata tagaaaagag gtacgtatga gtagcacaat
    18421 caaatcaaat cgaataaaag gtataatgtt tataatagca tcagcgcttg gctttgcaat
    18481 gatgtctgca ttcgtaaagc tagctggaga tttaccaagt tttcaaaaag tgttctttag
    18541 aaatctggta tcagctataa tagctttttg gcttatcata aaacataaag gaagtctaac
    18601 tggtaaaaaa gaaaatttaa aagtactttt atataggtca atatttggaa ctctaggagt
    18661 tatatttaac tactatgcaa ttgacaagtt gatgctttca gatgctaata tgctaaataa
    18721 aatgagtccc ttccttgtag taatattttg tgcaattgct ctaaaagaaa aaataaatgt
    18781 aaagcagata ggagctatta taattgcatt tataggagct ttattcataa taaaaccaac
    18841 atttagtgta gaaataattc catatcttgg gggaattgca ggagctgtat ttgcagcaat
    18901 ggcatatact tgtttaagag ttcttggaga tagagaagat tactatacaa ttgtattttt
    18961 cttttcagtt ttttcattag ttactgtagg gccaattgct tttgcagtat atgaaccaat
    19021 gacccttatg caacttatat atctattact agggggagta tttgcaagtc taggtcaatt
    19081 tggaataact ctagcatata aatatgcacc tgctaaggaa atctctatat ttgactatag
    19141 taatataatc ttttcagcaa ttttaagtat attcttattc aatgtctatc cagatatgtt
    19201 aagtgttgtt ggatatttaa tagtattttc ggcagcattt tatatgtttt tatacaataa
    19261 gaagttagat aaattagaca aagaaaagaa gaagtaaact agataaaagt gtttttataa
    19321 tttgtattga atatttaagt ctttgtatta aaattaaaga aaatttaatt aaaaatgttt
    19381 ggtatattaa cttataacag cagttaaaat tgaaaaatta taactgctgt ttcttttatt
    19441 aaaaatatcc aaatgtctgt aaaaatagac tataatagag tagtataaat aatataaagg
    19501 ggataaatta aagtatggaa aaagtgaaag ttgctgtgat tggagcaggt aatagaggaa
    19561 cgtatgcata tgctccatat atttatgaaa attctgatgt atgtgaaata gttgctgtag
    19621 cagaacctaa aaaaggaaga cgagaactat ttacacaaaa atataaccta gatagtaaaa
    19681 atgtatttga aactttagaa gactttttta aacatgacaa gatggcagat gcagtaataa
    19741 tagctacaaa tgatgataga cattatgatg tagcaaaact agctcttgaa aaaggttatc
    19801 atgtactatt agaaaagcca atgtctaata gtttagatgg tctggtacat atagatgact
    19861 tgtgtgataa gtataaagat aagattttta tgatttgcca tgtactgaga tattctccat
    19921 tttataataa attaaaagaa attgtagaaa gcaaaaaatt aggagagcta gttagtatac
    19981 aatataatga aaatatagga tattggcatt ttgcacatag ctttactaga gggaattgga
    20041 gaaatagcaa tgaaaccagc cctttaattt tagcaaagag ttgtcatgac atggatattt
    20101 tgttatattt agtaggaagt agatgcaaaa aaatatctgc atttggaagc ttaaagcatc
    20161 ttaataacca aaatgctagt ggagagatgg cacaaaattg tcttcagtgt ttagttgaaa
    20221 aaaaatgtcc atattcagca aagagaattt atttagaaaa agatagaagt ataaatagag
    20281 ctgttcacat aaatccaact gaagagaatc tattaaatat acttaagaca agtccatatg
    20341 gaagatgtgt ttacagatgt gataataatg ttgtagacaa tatggtaaat atactacagt
    20401 ttgaaaatgg agtgacggct acttttaatt tatgtgcatt tactaaagaa aatggaagaa
    20461 ctataaagtt aatgtttagc catggtgaag ttggtgggga tttaaataaa aatgagataa
    20521 gaattaaaga atttggaaaa aacgaagaaa tagttatgaa tccatcaaat caacagaata
    20581 tggtagagga atatgataga aatcttatag ctgaatttat taaattagtt tcaaataaag
    20641 aactagaaaa gggtagagta gcagcaaaag aagctataca aagtcatgta atggcatttg
    20701 cagcagaata ttctagggtc agtgatgaag tagtgtatat agaagaattt tttgatagtg
    20761 ctaagcaaat gactaaggag atagaagaaa ctatatttta attaataaaa atttattaaa
    20821 taaaataaag atagattaaa taatagaaat acgaaaatat gtgttctatt aaggaatcta
    20881 tcttttttat taaggttttt tcttatccct atcaaaaaaa tccatacatt ctgataaaag
    20941 ataagaaagt aaagcgaata agatttctgt acttaaagga atcgttactg aatccataaa
    21001 ggtatcaatt atgttcatag ctagaaaagt tagtataaaa tcaattataa attcgcaaag
    21061 tttatatatt gagtatggta atttgtttac atatctgaat atatctaaaa tagtagtgca
    21121 tagaaaatca attggagtgg ttatacaaaa atatattaaa aagaaaatta atacagctcc
    21181 aagagattta tattcaaatc ctaagaatga taagaagcca attcctataa ccgtgaaaat
    21241 acaaaaagtt ataccaaaaa aaacagcaaa aaataaaaat acagaaataa attcgcctaa
    21301 aggaatcctt cttttattac ttatcttaat caactcctta atttatgata tgaaatttat
    21361 ataaataata acattcttaa aaattcataa tagtcctctg tttcaaatag tactgtttga
    21421 gaatctattt ttttcatatt tggataaaaa gaggccttaa aagctttata atgttctcta
    21481 aattttattt ctatcttaaa tttatctggc aattttatta agtgcctaga taaatctcca
    21541 gataaagctt ttttgacacc tttttcaatt ttttttagtg caaggtttgg atggattgaa
    21601 attgaaccat ttccaattcc ttttgacaca ggaacagtga ctatatttgg atttagtttt
    21661 tttgcactct cacaaagcat ttcatctcca cttaaaaatg ctacaggaac attataatat
    21721 gcagcaatat aagcatttat agtaaattca gatgctattt catcatttat tttaaaatag
    21781 tcataatcaa tatccatagt atgggaaagt ggattaccat tacaagtagc tccagagtga
    21841 tagccggtga atatacatgc atcaaagctt tcatcaattc cagccatcat aactagtggg
    21901 tctttggtcc atcctctaag tattttgacg ttttcaggta aaatatttgg attaatattt
    21961 ctaccactgt catgtgcatc tttaacaagt atttcatgta caccagattg agtagctcca
    22021 tcacatgctg ctgttatctc tttactcatt tgtgttctat agtgttgcga aaattcacat
    22081 tcaagttttg tttcatccca atttacaata ccacaagtac cttctatatc agcacttaaa
    22141 tacaatttca taatatatac ccccttatgt ttattattga tgataataac agataacaga
    22201 aaatacataa tcaataaagg gcataaaaat attatgtctt actattaatt attattaaat
    22261 ctgtaactga aaaataacta aattggtatt aaaaaatata acactatgtg tcatttattt
    22321 atatagtttt tatatctgat gtttatataa aattgtaaca tataagtggt tacatttact
    22381 agtttaacat agttaaaata gttaggtatt atttttaagt taaattgatt attataaaat
    22441 cgcagaataa aagaaagatt taatttatta aaatgcatga aatgtttttt cctcaacata
    22501 atgctaaatt aaactcaaaa agaaataata gaaaaatctt atgtagctta gaaagaatgt
    22561 gaatgattta agggaaaaat agaaatttat tatataatat taggctgtat tatataatac
    22621 agcctaatat tatatgtata tgtgacataa aatcttggta agtgtaaata aaataaatgt
    22681 ggaaaacaag ttaatgaaat caagaaaaaa gtaatttaaa attcaatttc atcttcccaa
    22741 ttaaattctc ctgatttttc tacactctta ggccagtgac tacaccattt aggaatggac
    22801 ggattttcaa ccctatcaac gcttggagta tatggcttta agtctataac aggactatta
    22861 tcattagcat caatatatgg tatttttatt ataccatttt catggtcgat attgataatt
    22921 tgtacagcag tcaatgctat tggattgggt cttataggtg accttgttgc aaatattcct
    22981 ataacgtctg gtccactttt ataaggtttt ggggtttcta aaatacttct tagttcagga
    23041 ttatcaaacc catcagccca ccaaaataca tttaaatgac tgaaatcgtc gagttcattt
    23101 aatgcaggta catacttttt gtctaattta ataaagacct cttcgccttg aatacatatt
    23161 ttacctatag gatttattaa tatttctttc ataatattac ctccaattat ttaatttatc
    23221 atttgtaatt ttagggtata acatgacatc atgtgagggt caatataaaa taataaataa
    23281 aaatattaat agttagaatg ataatacatt ttttacatgg agcatgacac cagtaataag
    23341 gcaatcttcg tcaatatcaa aagtagaggt atgcaaaggg gaagtaatgt ttttttcacg
    23401 atttgcacaa ccaaggtggt aaaaagctcc ttcacagtgt cttagaaaat acgaaaagtc
    23461 ttcagcccca agagtgggcg agtctttaag gataatattt tcttctccaa acaattctac
    23521 agcattttgt ttgacgtaat ctactagatg gtttgaattg ataagagctg gataaccttc
    23581 ctcaatttca acagaaatac ttcctccaaa tgttttacaa gtaaaatcgc aaatttctct
    23641 aattcgtttt tttgaaaact ctctagtttc aggagtcaag gttctcaaag taccccttat
    23701 aaccacttta tcacaaacta tattttcctt gattccacct tcaatctttc ctagagaaat
    23761 aaccacagaa tcagttggat ttgtgtttcg actaacgatt gtctgtagag ctgtaataat
    23821 atgagcagat ataacaatag catcaatacc ttgatgtgga taagctccat gacattttga
    23881 accatgtaca gttaattgaa gtgtatcagt ggaagcattt agagtgttgt attttaattc
    23941 aattagattt ttgttgatat tggaatttac atgaagtcca aatatatatt ttacatttgg
    24001 gttttcaaga catccatctt ctatcataag ttgagcccca ccaatagttt cctcggcagg
    24061 ttgaaaaaag aattttacat ttacatttaa gtaatccttt aatttaaata gtatattaca
    24121 agtacccagt aaaatagcag tgtgtgcatc atgaccacat gcatgcattt tgccaatatt
    24181 aatagattta taagaataat taagttcttc tgttataggt aaggcatcta tatcagctct
    24241 tatagcaact gtttcaaagt ttggactcac gttaatgtat gcagttatcc ctgtatgatt
    24301 cttatattca atataattta tacctatttc atttaagtat ttaataattt ttttcttagt
    24361 ttgaaattct tctaatccaa gttctggagt cttatgtaaa tctcttctta tatttataac
    24421 ccaatcattt atctcatgac aaagagtttt tatattaagc ataaaacaca tcctaactat
    24481 attaaaaatt tatttttctt cattaattat attattttat gtaaatcatt attatgtatc
    24541 aagtacaaat aaaatatctt ataattatat tagagatatt tagtatggag aagaatatat
    24601 cattttataa gaagaggtgt ttaaatgtta ggaataattg cgccatctgg gccattaaga
    24661 aatacaagtt tggaggaaat aaagtttaat ttagaaagtt atggttatga agttaagttt
    24721 tctgaaagtt gtagtttaaa ttataaaggt tatttagctg gtaatgatga tattagagca
    24781 agggatatag aagatatgtt tttagataaa gatgtagata taattatgtg cttaagagga
    24841 ggttatggaa caacaagaat attggataaa ataaattatg atataataaa gcaaaatcca
    24901 aaaccattta taggtttttc tgatataaca ggtttaaatt tagctttcta taaaaattgt
    24961 ggtcttttac catatcatgg aataatggca gcaaatgtag gtaaatggga taaatttacc
    25021 tataaatcat tggtaaatgc tttagaattt aaagatgaat tatatttaga aaatccaaaa
    25081 gaagaaaaga tttatactgt atgtgaaggt aaagcagagg gaataataat gggaggaaat
    25141 ttatccttaa taattgccac aatgggaaca aaatatgaaa tagatgcaaa agataaaatt
    25201 ttgtttattg aggaaattgg agaacctcaa tataaactgg atagaatgtt aacacaacta
    25261 tattcttcag gaaaacttga ggaatgtaat ggtataattt ttggagattt taaggattgt
    25321 attgaagaaa atgatttgat ggaattacta atagaatttg caaataaggt caataaacct
    25381 tctatatata atcttcagtc aggacattgt atcccaatga taactattcc tttgggcaga
    25441 atgtgcgaat tagatgctac agaaaaaatc gttaaattaa aaaaatagtg tgtatataaa
    25501 tataatagaa atatggtata atcttataca agtaaaaatt tagctaggag gatgaaaaat
    25561 gtctgatgat agaataatag actttaacga actaaagaac aaagttaaag attctgatgt
    25621 agataaattt gagcaataca tatataactt atatttttct gttatggatg gaaagatgtc
    25681 tatggctgag ttttcaagaa aaatattcga ttatatgaga gataacaaca tatctcaaga
    25741 aaaatttatg aaaatacaaa agcaatttat ggagagatat ggtatggaca ctgaagaagt
    25801 agaaaaacaa cttagaaact ttggaatcga cccttctacg gcaggtttta tgagtaataa
    25861 tacttccagc aaagtatcta cagaagattt agagtcattt aagaagagtg caggatttta
    25921 tgagaaatat ggagaaaaaa tccaaccaaa gagttgtata acaacattta taaaaaatga
    25981 cttaaatgat attaatgtaa taatcgacca agaaaagata atgctttgta gtgatagaaa
    26041 aataaatctt atggattcag aactaaatga gtttttatta gaatataaga atatgtttaa
    26101 taaaaaaata aaggtagtaa tgtgcgaaac tacgaataag tatgattatt aaaaaatgaa
    26161 tttaaatact gaagtagtat caattaattg tactacttaa aaataaaaat cgcaatttat
    26221 tattccttat aaatttgtat aaggaatatc taaactgcga ttttttatat tgtgaagatt
    26281 agtaataata gatagtgttt taaattgtaa tcttctcact aaaactgtgt ttttctatta
    26341 gaaattttat taaaaataaa tatctgataa ttgtattata tgggatgtaa agtattagaa
    26401 gcttaacgaa tctcttttaa tacattaact ccattttgaa tcatactgtt gaaaaatact
    26461 aagtttaaaa tctcagcagg gtgaacgtta ggaatatcat aagtatctac taaattcata
    26521 ggtacaacta tatttttttc aatattatgt tgattaaaat atgattttag agttattgca
    26581 aattgatata tacatatatc tgtgcaatcg ccaactataa ttatattatc tatattatca
    26641 aaatccaaat tttctaatgc aaaaaaacca ttagtagaat ttttaggaag aatttgtagg
    26701 ttttctatcg acttaagttc atcaaccaat tcactttcta catcattttc caaacagtga
    26761 acaggataac tcaaaagttc tattgattta ggagtatgag aatcagtaaa tgctattact
    26821 ctatttaatt tgtttgatat tttttttgta aacatttcaa ttggctttat taaagactct
    26881 actctaggag agtataatgc accttgtctt gcaaagccat tattaacatc aattataaat
    26941 aaagcagttt tactcaaatc ataattttct attttttcta ttggtagatt atctaaatta
    27001 ctctttaaag cttcaagttc atttaataag ttatccatag ttatacctcc aagataaatt
    27061 taataaaatt gtacatatta attatataaa agtcaaggag tacaaactat tgtataatta
    27121 gctgtattgt tttgagtgta aaagatttga agcaatatct ggatagttag taaaaatacc
    27181 atctacattg agttttagac agtgtagtat atcatcctct tcatttacag tatatacatt
    27241 gacaccaagt agatttttgt gacaaagttc aattagagat tcatttacta aaactagagg
    27301 tggatgaaga taactattac ccagaaattt agcaaaattg actacattgt ttataggtaa
    27361 ataacacaat aatcctgttt ttacactagg gtctaattta tgaaagtttt ttaagctatt
    27421 gctgttgaaa ctagatataa gaactctatt tttcatatta tactttaaaa taagctctaa
    27481 aacgcctttt tctatattgg gatagtttat tttgtcagtt tttagttcga tatttaaagt
    27541 aaggtctgta ggtgagatta gaattaatac ttcttctaaa gttggaattt tacattcttt
    27601 attgctttga tatccttcaa aagatgagtt tagagttttt aattttctta aagtaaagtc
    27661 ttttacaaaa ccatgtccat taaaagttct atcaaccttt tcatcatgaa taactacaat
    27721 ttttccatcc ttagttctgt ggacatcaag ttctattcca tatatatcca tatccaaaca
    27781 ttttttaaaa gctagaatag tattttctgg atactttcca ctaaaccccc tatgagcata
    27841 aatattcatt tatatggttc cctcctataa gtataactta tcttataaaa atttaattaa
    27901 tataatatat catattccaa aaggtattgt tatatattag ttaaataact atttgtaatt
    27961 tatatattat ataaatgtag aaaaataaaa tcatatatgt gttataatat attttaaaca
    28021 ttgtaaatat tacgaattta gtagtcataa taagtgtaat tttatgcaag ctcatgtttt
    28081 tagagcttgc atatgtatta ttaatatatt tatatattgt gaaaataaaa ttccaaaaga
    28141 attttttcta tagacttagt agtaaggggg aattttgata tgtatgaagt taatttagaa
    28201 cgagctatga attattggat ggatttgtta gatgattata cgaatatagc aaaaattcca
    28261 aatgattttt tttataaaga ttgttctgat gaagtagtag atgaggtttt taagatgaat
    28321 attgagaaac atgaaaggtt aattcaatat tctaaagtga acaatattag catagactct
    28381 atcatagaaa ctatatatgg ccttatactt caaaagtata tatatgaaga tgatgtagtt
    28441 tttggtaaaa caatgaatat aattccaata agagtaagag ttagacaaag tgaaaaattt
    28501 atagatgttg taaggaagct aaaaaggcag tggagcaggt ctttagagta tggatactat
    28561 ttgttatcag atatagagaa taaaaatcat ctaaatacta agcttataaa cacaatattt
    28621 atagctaaaa gttttgattt atcatatgat tatgacatag aaaaaaaagg atatgattta
    28681 tctgtaatag tatatactaa gagggcactt aaaataaaaa taaagtataa accatctata
    28741 tataaaagag aaactattag aagaatttta aatcaatttg attatataat agagcaaata
    28801 atagaagata atgatatttt aatagaagat ttagaatttg tatgtaagga agaagaaaaa
    28861 gtattattgg aagactttaa taataatcaa tatgaagtac cctatgataa aagttatgtt
    28921 gatttattta gggagcaagt taaggtaaca cctagtaata tagctgctag ggatgaaaat
    28981 agaaagttaa catataaaga attggatgaa gtaactgata aacttgcagg ttatttaaat
    29041 catataggag tggaaagtga agacatagta gctgtaatgt taccaagaga tattaacata
    29101 attattacag caatagggat tatgaaatca gggggagcat tttttccaat agacacaagt
    29161 aatccagaag aaagattgaa ttaccttctt gaagatagta atgcgaaagt agtgataact
    29221 acagatgaac tcaaaagtaa ggttgtaaat gagaatacca tagtactcga tataaatgat
    29281 gaagaaatgt ttaagtttgg atatgaatta actgaaaaaa taacatcatc aaattgtgca
    29341 tatacgatat ctacttcagg gtcaactggt aggccaaaga ccatagctat agaacataag
    29401 agtttagtaa atatgtgtta ttatagcgta aaatctataa gcgctacaga aaatgatata
    29461 tgtggtatat acttaagttt cagttttgat gctgtaatga aacaactatt cccttatttg
    29521 cttgtaggtg catcaataga tattatgcct gaagaagcta aatttgatga atatacagta
    29581 aatgaatact gtgaggaaaa tgacataact atactagcat tgccaacagc atttgcaagg
    29641 ttatttatac aaaattgcaa taataattca cttagagttg tacagactgg aggagaaaga
    29701 ttaaaaggat atagaaagcg taattatgaa ctatataatg agtatggacc aaccgaattt
    29761 actgttgtat cgacttcttt tcatgtggac agagaatatg gaaaaatacc aataggaaaa
    29821 cctatattta atacttatgc atatgtatta gataaaaaga acaaactatg tccaattgga
    29881 gcaccaggag agctatgtct atcaggcatt caaatatcaa gaggatattt aaataaaaaa
    29941 gggctaacag agcaagtatt tgtagagaat ccttacaaaa cttgtgaaca taataagtta
    30001 atgtatagaa ctggtgattt agtaagatgg ttagatgatg gaaatttaga ttatattgga
    30061 aggatggaca atcaagtaaa aattgatgag tttaggatag agctatatga gattgaaaat
    30121 ataataaata atattacaga aattaaaagt gttgtttgta tatcgagaac aaatgatgat
    30181 ggagatattt atatatgtgc atattatgta attgatgagg aagatagtgg taagataaat
    30241 gaaagaacta ttagagaata tttaaatgag catctacctc catatatgat tccaacaata
    30301 ataatgagga tagataagat accagttaca ccaatcggaa aagtaaataa aagagcatta
    30361 ccagaataat ttttttatta tgataggtgt cataaagtga tttcagacat ttctttatga
    30421 cacttatttt tataaaataa tcaatttgca taaaaacaag aattttctgt atatatttac
    30481 tatggtgaaa atttatttat aagaatgatt attgtatttt ttatactttt ccgtgt
//
LOCUS       DAYAOO010000044        30223 bp    DNA     linear   BCT 12-OCT-2024
DEFINITION  TPA_asm: Clostridioides difficile isolate ST8-SSI-h139-18
            SAMN40601845-rid21577343.denovo.044, whole genome shotgun sequence.
ACCESSION   DAYAOO010000044 DAYAOO010000000
VERSION     DAYAOO010000044.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN40601845
            Sequence Read Archive: SRR28438827
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 30223)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 30223)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-MAY-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-MAY-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002157583.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002157583.1
            Genome Coverage       :: 163x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/11/2024 16:19:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 4,038
            CDSs (total)                      :: 3,963
            Genes (coding)                    :: 3,930
            CDSs (with protein)               :: 3,930
            Genes (RNA)                       :: 75
            rRNAs                             :: 6, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 60
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 33
            CDSs (without protein)            :: 33
            Pseudo Genes (ambiguous residues) :: 0 of 33
            Pseudo Genes (frameshifted)       :: 7 of 33
            Pseudo Genes (incomplete)         :: 25 of 33
            Pseudo Genes (internal stop)      :: 11 of 33
            Pseudo Genes (multiple problems)  :: 8 of 33
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..30223
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN40601845-rid21577343.denovo.044"
                     /isolate="ST8-SSI-h139-18"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Denmark"
                     /collection_date="2018"
                     /collected_by="Statens Serum Institute"
     gene            <1..1143
                     /locus_tag="ACGI5H_002223"
     CDS             <1..1143
                     /locus_tag="ACGI5H_002223"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897944.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF5009 domain-containing protein"
                     /protein_id="HFG9697926.1"
                     /translation="ISNNAVDSKLMNSRIKSIDIIRGLSIALMIVCNNPGTWMRMYPQ
                     LRHAVWHGVTLADFAFPFFVISLGVTIPISINSKLKNNKSTLSIILSIFKRSILLILF
                     GFFLNYLGNPDLDTVRILGVLQRMGLVYFVTSLVYLLLKKLNVGSTATIITFLCISTF
                     IIVGYYILAKPYGFELEGSLAQLVDLHFFKGHLYKPEFEPDGFLTSIVAISSGMLGCT
                     MGCVLLKENIGEYKKFFKILVMSIILLIGAFIFNQYFPFNKRLWSSSFVLLMAGSYGI
                     LLSIFYFICDIKNKSKIFTPIIALGSSPIFTYMCLEILSHVFWNVPKLTNKVDYPTTL
                     VEWTTYELITPWAGTTWDSLIFSLLYVLFWVIVMSIMYKKKIFIKI"
     gene            1397..3421
                     /locus_tag="ACGI5H_002224"
     CDS             1397..3421
                     /locus_tag="ACGI5H_002224"
                     /EC_number="3.5.1.28"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009906102.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008745 - N-acetylmuramoyl-L-alanine
                     amidase activity [Evidence IEA];
                     GO_process: GO:0009253 - peptidoglycan catabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase"
                     /protein_id="HFG9697927.1"
                     /translation="MKKTTKLLATGMLSVAMVAPNVALAAENTTANTESNSDININLQ
                     RKSVVLGSKSNASVKFKEKLNADSITLNFMCYDMPLEATLNYNEKTDSYEGVINYNKD
                     PEYLNVWELQSIKINGKDEQKVLNKEDLESMGLNLKDYDVTQEFIISDANSTKAVNEY
                     MRKTSAPVKKLAGATRFETAVEISKQGWKDGSSKVVIVNGELAADGITATPLASTYDA
                     PILLANKDDIPESTKAELKRLNPSDVIIIGDDGSVSQKAVSQIKSAVNVNVTRIGGVD
                     RHETSLLIAKEIDKYHDVNKIYIANGYAGEYDALNISSKAGEDQQPIILANKDSVPQG
                     TYNWLSSQGLEEAYYIGGSQSLSSKIIDQISKIAKNGTSKNRVSGADRHETNANVIKT
                     FYPDKELSAMLVAKSDIIVDSITAGPLAAKLKAPILITPKTYVSAYHSTNLSEKTAET
                     VYQIGDGMKDSVINSIASSLSKHNAPTEPDNSGSAAGKTVVIDPGHGGSDSGATSGLN
                     GGAQEKKYTLNTALATTEYLRSKGINVVMTRDTDKTMALGERTALSNTIKPDLFTSIH
                     YNASNGSGNGVEIYYKVKDKNGGTTKTAASNILKRILEKFNMKNRGIKTRTLDNGKDY
                     LYVLRNNNYPAILVECAFIDNKSDMDKLNTAEKVKTMGTQIGIGIEDTVK"
     gene            3641..4327
                     /locus_tag="ACGI5H_002225"
     CDS             3641..4327
                     /locus_tag="ACGI5H_002225"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891044.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar transferase"
                     /protein_id="HFG9697928.1"
                     /translation="MSGYTNDECEIPKIKSYPGADKEIASEIDYSIVKGTVLFDLYQR
                     IMDLVLSIIGLVIGLPLIAIFGILIKIEDKGPITYKQERLGKCGRRFYIYKLRSMRTD
                     AEKFGAQWAEKDDPRITKVGKFIRKTRIDEIPQLFNILKGDMGLIGPRPERPNFTVQF
                     NEEIPGFINRLAIKPGLTGWAQVNGGYEITPEEKLKEDIYYIKNRSILLDFKILFKTV
                     KVVLTGDGAR"
     gene            4422..5477
                     /locus_tag="ACGI5H_002226"
     CDS             4422..5477
                     /locus_tag="ACGI5H_002226"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861676.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall-binding protein Cwp7"
                     /protein_id="HFG9697929.1"
                     /translation="MIKKISTILSLVLLISISSTIGVFADANPKRELIEGSIPEISTE
                     LNKRAFKDSKEVILVNEESIVDSISATPLAYAKNAPIVVTKSKNLGRVTRNYLKELGP
                     EKVTIVGGLKAVSKDAERNIEKMGMKVERIRGKDRYDTSLKIAREMYRTVGFDEAFLL
                     SSTTGLENAISVYSYAAKSGMPIIWAKDEGFEEQIDFLKGKNLKKIYALGDSKEFIAE
                     IDSNLKNIEGIKQINKSSTNVDLIKKFYDEKDIKKIYTARLDFGSRSDVNEYISLGVV
                     SAKENMPILICSDNLSRAQDKFLKDSNINDVVEVGYTVGDYSLFKSIFNLTFLSCIVL
                     ILLLLLITFRALRYESK"
     gene            5592..7148
                     /gene="murJ"
                     /locus_tag="ACGI5H_002227"
     CDS             5592..7148
                     /gene="murJ"
                     /locus_tag="ACGI5H_002227"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454106.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0009252 - peptidoglycan biosynthetic
                     process [Evidence IEA];
                     GO_process: GO:0034204 - lipid translocation [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="murein biosynthesis integral membrane protein
                     MurJ"
                     /protein_id="HFG9697930.1"
                     /translation="MSKTAKAALWIMAATMFSKVLGFLRELVLANFYGTGMYADVFVL
                     TLNIPGLIIAVIGSAVATTYIPMYFETKKRLGDEGALKFTNNVLNICYIMAIVIAIIG
                     LLFTEQFVTVFAAGFRNDPAKFQAAILFTKIMISGVLFLSGSKIFSSFLQVNDSFVIP
                     GLIGIPYNIIIIAAIALSAGKNVWILPAGALLAMASQLLFQLPFAFKKSYKYKPYINL
                     KDESIKELVNLVLPMLVGVAVGQLNIFVDRLLATTLGDGKLSALNYANRLNEFVMALF
                     VTSIITVIYPKLAKMSGKDNKEGFISTIVKSSNCIILVVLPISIGAIILAEPLVRILF
                     QRGKFDALSTDLTSIALRLYSLGLLACGVRDVLYRAFYSLSDTKTPMINGSIALIINI
                     VLNLILIRPLGHAGIAISTSTSNIITVILLFISLKKKNGYFGGDKIIKTGLKSLVASG
                     VMAVATLLIYNNLYAFMGSGTIKEIISVGAGVLGGASVYTVLIVLFKVEEMDLAFEFL
                     RKGKQKLLRR"
     gene            7194..8900
                     /locus_tag="ACGI5H_002228"
     CDS             7194..8900
                     /locus_tag="ACGI5H_002228"
                     /EC_number="5.4.2.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897940.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016868 - intramolecular
                     phosphotransferase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phospho-sugar mutase"
                     /protein_id="HFG9697931.1"
                     /translation="MDYKNNYEMWLNSPYFDEQTKNELLSIKDDEKEIQDRFYKNLEF
                     GTGGLRGIIGAGTNRINIYTVRRATLGVLNYIMKTQGEEGKQKGIVIAHDSRYMSREF
                     CIEVAKTLSAYGVKAYIFEELKPTPELSFAVRYLKCAMGIVITASHNPKEYNGYKVYD
                     SDGGQICIDMANDIIAEVNKIDDYSTIKSIDFEEALSKNLITILDNEVDDEFIKAVKK
                     QVLRQNIIDEYGKKLKIIYTPIHGTGNKPVRKVLNECGFENVMVVKEQELPDSNFSTV
                     KYPNPEEKSVFNIAIEMAKNNGTDLIIGTDPDCDRVGIVVKDSSGEYVVLNGNQVGSL
                     LVRYILESLVEENKLPKNNPTIIKTIVTSELGAKIAKAYNVDCLNTLTGFKFIGEKIK
                     AFEESNDRSFIMGYEESYGYLIGTHARDKDGVVSSLMICEMAAYYSSKGMNLYEALID
                     TYNKFGYYKEDLKSVTLKGIDGIKKIKEMMLYFRSVKIDNVADVKVDKILDYKDGVDD
                     LPKSDVLKFLLEDGSWIAIRPSGTEPKIKFYFGANSDNQEDVEFKLNNLISYILNVVD
                     SI"
     gene            8922..9995
                     /locus_tag="ACGI5H_002229"
     CDS             8922..9995
                     /locus_tag="ACGI5H_002229"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426511.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mannose-1-phosphate guanylyltransferase"
                     /protein_id="HFG9697932.1"
                     /translation="MKVYNVIMAGGGGTRFWPLSRQEVPKQLINLSGEDALINETINR
                     IDSLAKKDDLFIVTNEKQLEALKDIVKDKCLDSNILPEPCARNTAAAIGFAAFNIMKK
                     YGDGVMCVYPADHYIKDEKEFKSILEKAIYIAENNDKLVTIGITPTFPSTGYGYINFN
                     RENTIEDVAYEVVEFVEKPNYEIAKEYVNSKKYVWNSGMFVWKVSKILEDFKRYLPKV
                     YEKLEDISKYLGTKEEMEKIKEIYPTIQSISIDYGIMERSNDVIVVPGDFGWNDVGSW
                     DSLGAIYPTDDEGNIKRGENITIDTKNSIIYSDDKLISTIGISDLIVVSTNDAVMVCR
                     KDKAQDVKKIVEQLKEEDRQEYM"
     gene            10007..10729
                     /locus_tag="ACGI5H_002230"
     CDS             10007..10729
                     /locus_tag="ACGI5H_002230"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897939.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HFG9697933.1"
                     /translation="MIPKKIHYVWFGGPKGNIENICINSWKEKLPEYEIVEWNEKNFD
                     IEKEIKGNKFLEECYKRKLWAFISDYTRIKVLYEQGGVYMDTDMQILKDITPLLENNR
                     LICGYEDDREYINGAIIGVEKGHPFLKDLLEYYEKEVLTSSLFTIPKIMTHLMEKNYK
                     KIDPNNYEEGIRVYDKEYFYPFGFKEDFTPECITENTFGIHWWGKSWAKKRNYFLESK
                     HLTGVNKIWKCCKIFASNTLRS"
     gene            10745..11902
                     /locus_tag="ACGI5H_002231"
     CDS             10745..11902
                     /locus_tag="ACGI5H_002231"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897937.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide polymerase"
                     /protein_id="HFG9697934.1"
                     /translation="MKTLNDDRNIMIRKYLYIFVLFIILLRKYMISFIDPNMDIGMIK
                     SALFYSSIGILMLLFLFDKRKSITEMVLVGVCVLLYLLNREGAILLIVLLAVSAKQID
                     DKFIVKNYLIISACFLMVAILLFNLFPSLIFNQEVHYRYIEKIDMLVTRMDFGLGNPN
                     SVFYHMVTIYAAYIFLRYKDYNKWDRIILFGSAFFVYQTTYSRTGFFTILAGLIFVEI
                     IRWIDIKKIKGLPMLLKTLPIILTLFSVIIGTVFDKSTLLNRLLASRPKFWHVYLAEK
                     GNFLKPFGNSYSPAIKATNPLDSSYVYIISVLGVVACILFMYLMYKGIESFIEKDKKA
                     YLVALFIFLLYSFAENLLLEASFSFAVVLLIKEVILNDKREIDLWKMKSRR"
     gene            11905..12744
                     /locus_tag="ACGI5H_002232"
     CDS             11905..12744
                     /locus_tag="ACGI5H_002232"
                     /EC_number="2.4.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009906099.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016757 - glycosyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HFG9697935.1"
                     /translation="MLISLIMPTLNRYDDIYLLMDSLENQTYKNFELIVVDQNDNSKV
                     KEIVDKYIDKLDIKYIKSSKKGLSYNRNVGIDNAVGQIIGFPDDDCVYENDTLEKVIN
                     FFNKNKDYKIYSCKTMDSNKVDAFKKMYDGTCDITSSNVLDTITSITFFIDFEGKDYT
                     RFDEKLGVGGEFGAGEEIDYVLNLLSLGFKGKYFGNDIIYHPAKKHSKSKEKYQKDYN
                     YGRGFGALCKKEIVYRKNYKFAKVMVSKLVRNIGGLILSSNRDYHSATIKGRINGFRQ
                     YKL"
     gene            12759..13934
                     /locus_tag="ACGI5H_002233"
     CDS             12759..13934
                     /locus_tag="ACGI5H_002233"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728923.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CDP-glycerol glycerophosphotransferase family
                     protein"
                     /protein_id="HFG9697936.1"
                     /translation="MDKVKFLINMLLAFFIYPFNKHKFNGRDIWLIGGHSGDIYNDNS
                     KFFYEYMLKEHNDVETYWVVNKDSKVFDKIPGKKLIRGSVENYLYYYNSKAIVFSHAP
                     SADIAPYNFAVPVLNYFHKKTIKVFLNHGTISFKKRKPMNKKFKNIIDNLYKSYNIVT
                     ASSEFERNVMVNDWGMLDDSVYIIGNARYDNLPTNEVAQTRDILYTPTWRDWIKFSSG
                     KFTDTDYFKNIMNFLNDDKLNKILDEKDINVKIYMHHLMHEFIDDIKENITGKRIVFL
                     DKGVTLANEIRKSAANITDYSSVAIDFLYMNRPILFYQFDLDEYMEKVDSYIDLKSEM
                     FGSLAYNNDEAVNKLIDIIENNFEVMDNQKNERNKFFRYNDNKNCKRIYDCVLSKIK"
     gene            13963..14712
                     /locus_tag="ACGI5H_002234"
     CDS             13963..14712
                     /locus_tag="ACGI5H_002234"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426502.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HFG9697937.1"
                     /translation="MKKNLVSIITPMYNSEKFIEATIKSVLNQTYQEWEMLIIDDCST
                     DNSPNIVKSYMQQDSRIKCIKTETNKGVSNARNLALSKATGQFIAFLDSDDQWNSSKL
                     EKQVNFMLENDYVISFTSYELMDENDKKLNKVIKVPPNVDYRRLLKGNILGCLTVVID
                     KSKLDFEIRMSGVRHEDYVLWLSILKKGHIAHGINEVLALYRKSSNSLSGNKIKAAMW
                     TWNIYRNIEKIPLYKAIYYFINYGINGIKKS"
     gene            14734..15642
                     /locus_tag="ACGI5H_002235"
     CDS             14734..15642
                     /locus_tag="ACGI5H_002235"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426500.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HFG9697938.1"
                     /translation="MYKYKFTVFTPTYNRAHLLENLYNDLKAQTYDFNDFEWLIVDDG
                     SSDSTKELVEKFISENKLNIRYIYKENGGKHTAINLGVKNADGELFFIVDSDDGLIKD
                     SLEIANDEWDSLENKEGFSGVVGLCVYPSGDLIGTEMPEDKKICHFADLYFKYGVKGD
                     KSIVFVTDELIKFPFPERKEVRFLPESVVWNEMSKYYKVICVNKPMIIRDYLDDGLTK
                     NILSKNALRGRALEFLYLINQNTYPLSRYPYMWIKNYINLARYSLLSDSHYFGELRKV
                     SDKLLYLALFPLGYYKYIGQRKLVSK"
     gene            15690..16442
                     /locus_tag="ACGI5H_002236"
     CDS             15690..16442
                     /locus_tag="ACGI5H_002236"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422866.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HFG9697939.1"
                     /translation="MNEPLVSIITPVYNSEEFLSETIKSIQNQTYKNWQLLLVDDCSK
                     DNSSEIIKSFRKEDARIKYIKLEKNSGAAVSRNVGIKNAEGRFIAFVDSDDLWDSRKL
                     EIQIEYMLKENVGFSFTSYRYMRQDGSKTNKVARAPKKIDYEGLLRNTIIGCSTVVID
                     KEIVGEFSMPLVRRGQDTATWLQLLKKEKYAYGIQEDLVNYRLVGNSISSNKIKALKR
                     TWNTYRNVENLSLPKSLYVFCFYVFNAIKKRV"
     gene            16396..17763
                     /locus_tag="ACGI5H_002237"
     CDS             16396..17763
                     /locus_tag="ACGI5H_002237"
                     /EC_number="1.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893725.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016616 - oxidoreductase activity, acting
                     on the CH-OH group of donors, NAD or NADP as acceptor
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-glucose/GDP-mannose dehydrogenase family
                     protein"
                     /protein_id="HFG9697940.1"
                     /translation="MYFVSMFLMPLKKEYKFYILGGKKMKIAIAGTGYVGLVTGVCLA
                     EVGNENVVCVDVDEQKVKSMKLGIAPIYEEGLEELMVKNYNRGRIDYTTDYKKAYEDV
                     DVILIAVGTPERSDGSANLDYIKAVAKQIAETVTKDTLVVIKSTVPIGTNEEIEDYIN
                     RNLKNDVKVELASNPEFLSQGTAVKDTLHASRIVIGVESEWAREILEEIYKPFNQPII
                     VTNRNSAEMIKYASNNFLALKISFMNDIANLCEIAGANIEDVALGMSYDDRIGSKFLK
                     AGIGYGGSCFPKDTKALHWLSEHNGYELKTVKAAIEVNESQKLKLVRKASKLVESFQD
                     MKVAVLGLTFKPDTDDIREAPSIPNIKYLLERGARVTVYDPIGVNNTKKIFGDSILYA
                     DSVDDAIEDAEICFIMTEWKDVLNYDIHKYKEKMKNPLVLDGRNCYKIKDMEELGIEY
                     YSIGR"
     gene            17769..18860
                     /locus_tag="ACGI5H_002238"
     CDS             17769..18860
                     /locus_tag="ACGI5H_002238"
                     /EC_number="2.4.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728922.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016757 - glycosyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HFG9697941.1"
                     /translation="MKTVCYLADGSNPHTLKWCSFFKNKGYDIHVISLNGGHMEGIKI
                     YNFGSNVEELKNENISKKTGYLGSIKQIKKLVNEIKPDILHAQYASSYGFIGSLLGYH
                     PYIISVWGTDIYDFPNNGFIQKQIIKHNFRKADYIFSNSRDMAKEANKYTAKHVDVTF
                     FGVDMDRFKPMEVEKEDAFVIGIIKSLEKKYGIEYLIQAFKMLKDEYKDKKIILKIGG
                     SGSQMDNLINLAKELGIENDVQFLGRISPENVSKTFNSFDVTVFPSLREGFGVAAIES
                     EACEVPVIVTNVGGHPESVWENETGLIVEPKQPEEIKNAIIKLMENDELRLNMGKKGR
                     QFVRENYEVNLNFNDIEKIYDSIFDKYKK"
     gene            18944..20857
                     /locus_tag="ACGI5H_002239"
     CDS             18944..20857
                     /locus_tag="ACGI5H_002239"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728921.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide biosynthesis protein"
                     /protein_id="HFG9697942.1"
                     /translation="MRESIDLEKESFFNRLFKKYKFRHLTLLILDICSVLVAFRMSLS
                     LTGNLNAFTTNDIIISACIYIVLHIVSFRLFKCYNTLWRYAGEEEIISIFVATLAYLI
                     PIYIINKLLGFDYPIMFYVLNTIFIIMFTSGARIAYRAIRIVMNKTYSRGKVSNILII
                     GAGDAGEMVIQELKRNPELKKVAVAIIDDDKNKIGRIIHNVKIVGTTSDIKDVVEKYN
                     VDEIIFSIANIEKRRKKEIIDICKNTNCKIKTIPGIYEIIDGKVDIKQIREVEIEDLL
                     GREPIKTNLREISNYIEGKVILITGGGGSIGSELCRQIAGFNPKELIIVDNYENNAYS
                     IQQELLRKYKNKLDLKTVIASIREEKRMDEIFNKYKPEVVFHAAAHKHVPLMESSPGE
                     AIKNNIFGTLNIAGLSSKYRAKKFVLISTDKAVNPTNIMGATKRAAEMIIQTMNAESQ
                     TEFVAVRFGNVLGSNGSVIPLFKKQIEDGGPVTVTHPDIIRYFMTIPEAVGLVIQAGA
                     MAKGGEIFVLDMGEPVRILDLAKNLIKFSGFEPDVDIKIEFSGLRPGEKLYEELLMSE
                     EGLLDTEHKKIFIGRPIDVDREKITKYLKLLREITNNEEVEKIDGIMRELVPTYIKPE
                     DANIKEIATTREK"
     gene            21056..21763
                     /locus_tag="ACGI5H_002240"
     CDS             21056..21763
                     /locus_tag="ACGI5H_002240"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422873.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NlpC/P60 family protein"
                     /protein_id="HFG9697943.1"
                     /translation="MMNIKNKKHILKKFIAMVLIAGVVTVEAGAITASAAEPTNSPMS
                     ATVDQCDFLNVRSGASANDAVVGKINTGDKVEVLELHSNGWIKIKSVDNVTGWVNGDY
                     LTIQGGNVDAKVQNVLNLAFKQQGKPYKWGATGPNSFDCSGFTSYVYKNGAGVNLPRV
                     SRSQATVGKKVSRAELKPGDLVFFGSGGSINHVGLYVGDSKFIHSPQTGDVVKVTSMA
                     PGTNYARRLITATRVLQ"
     gene            22065..24176
                     /locus_tag="ACGI5H_002241"
     CDS             22065..24176
                     /locus_tag="ACGI5H_002241"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861673.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall-binding glycosyl-hydrolase Cwp19"
                     /protein_id="HFG9697944.1"
                     /translation="MKKISILVLSLIMTLTMCSVSSFADSSNDKEMRAAWISTVYNLD
                     WPKTKNNEAKQKKEYTDLLDKLKSVGINTAVVQVRPKSDALYKSNINPWSEYLTGTQG
                     KDPGYDPLPFLIEEAHKRGMEFHAWFNPYRITMADESIDKLPANHPAKKNPSWVVKHG
                     NKYYYDPGLPEVRKYIVDSIAEVVQNYDIDGVHFDDYFYPGVSFNDTATYQKYGKGQN
                     KDDWRRENVNTLLRDVKASIKSIKPNVVFGVSPAGIWRNKSSDPTGSDTSGNESYVGT
                     YADTRAWIKQGLIDYVVPQLYWPIGLKAADYSKLVAWWANEVKGTNVDLYIGQGIYKQ
                     GQSSYGGQNIAKEIVQQVTLNRKYSEIKGSMYFSAKDIANSTSIQKDLKSLYSSSEEP
                     VTPPSNVKVEKLRGDERYDTAVAISKKGWATNSDTVVLVNGYSIVDGITSTPLATSND
                     APILLVNKDNIPTSTKNELKRLNPSKVILIGGNNSIGDKVESEIKDTLSNVSINRVGG
                     SDRYSTSLMIAKELVKTNPVEKLYITSGTGEADSLSIASKAGEEKQPIVLVSKDNVSD
                     EVYNWISDLKVKDAYFIGGNLSISDSVINKLDKVITNDVSKNRIAGENREETNGKVIQ
                     KFYPNAEYSSMFVSKSNQLVDALTSGPLAAKLKSPVVMLGNSVTSAQKTALEPKKTTL
                     VYEAGDGINQNTLNTFLNLVK"
     gene            complement(24374..25339)
                     /locus_tag="ACGI5H_002242"
     CDS             complement(24374..25339)
                     /locus_tag="ACGI5H_002242"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454115.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0070726 - cell wall assembly [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LCP family protein"
                     /protein_id="HFG9697945.1"
                     /translation="MSKLKKFVILLAFLVVIFPISVYGYFYYKLSAIHDSSISSDLLD
                     NNDHKNEDGIINILLMGTDARPNEDSSRSDAMMILTIDNKHNDIKLTSLARDSYVDIP
                     GHGKQKLTHAYAYGQADLLIQTIEENFNIDIQNYACVNFESFMYIIDAIGGVEVTVEK
                     GEIRELNKFIPETYKWNKSDDKGSIQYIRNSGKQTLNGYQALSFARIRHNDTAFARDG
                     RQRQIIQAIIKKTETLPVTKYPGLLDAVLPYVKTNMKPNAILSLGAQVLKMGDLNIKQ
                     FEFPIDDEIHSTGGIYGKAGWVLRFDPDTLDILHDFIFNDIEFKQ"
     gene            complement(25624..26580)
                     /locus_tag="ACGI5H_002243"
     CDS             complement(25624..26580)
                     /locus_tag="ACGI5H_002243"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891022.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0070726 - cell wall assembly [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LCP family protein"
                     /protein_id="HFG9697946.1"
                     /translation="MSGLKKFVIFLALLVIAFPVSIYGYVFTKLKTIQDDSINTEALS
                     SNDYKNEENITNILLLGTDARPGEEVSRSDAMMILTIDNKNKSLKLTSLNRDTYVNIP
                     GRGEQKLTHAYVYGQANLLIETIEENFQLDIQNYAVVDFFSFMDIVDALGGVTVTVDK
                     SEIRELNKFIPETYKWNKNDNKGSLKYIRNSGEQKLNGYQTLAFSRIRKNDSTDERDR
                     RQRSVIQSLINGVKDLPVTKYPNLVNTILPYVKTNMNPNEIISLGKELLSIGNLNLKS
                     MEFPLSTENGRKIGNAGYVIPFEEYELDAMHDFIFKDIMVED"
     gene            26948..27736
                     /locus_tag="ACGI5H_002244"
     CDS             26948..27736
                     /locus_tag="ACGI5H_002244"
                     /EC_number="3.1.3.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893724.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family hydrolase"
                     /protein_id="HFG9697947.1"
                     /translation="MIKLIATDLDGTLLDEKSEINPEFYKVFKKLRERGIMFSAASGR
                     QYQNLIKKFEDIKDDMMFISENGTLVVYKGKEILSNPLNKELVNEIIETTRSIKGKKI
                     VMSGKKYAYIESKDEAFIQEVSTYYAKFKIVEDLTKVEGDILKIAVFDFKGAEHNNNI
                     YFEKFSDRAQVCISGVEWLDLTAKGANKGSAIKKVQKMLDIKYEETMVFGDQLNDVEM
                     MKSAYHSYAMENANEHLKQIARFRAKRNTENGVVDKIKEVIKIG"
     gene            complement(27859..28329)
                     /locus_tag="ACGI5H_002245"
     CDS             complement(27859..28329)
                     /locus_tag="ACGI5H_002245"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891020.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4358 domain-containing protein"
                     /protein_id="HFG9697948.1"
                     /translation="MKKILILFFSIILSLGMVSCSSSGDYKNVSTSKIKKALKSSDLL
                     IKESKIFDAKDFNYFNDVEEDIIQGFVINSSEKLSLEDIIVIKTDEVDKIYKTLENYK
                     KDMIQAPFGEGHGEKINSEIANNTIIEKAGRYVYLISAENATQIENKILNIIKK"
     gene            28468..29112
                     /gene="uppS"
                     /locus_tag="ACGI5H_002246"
     CDS             28468..29112
                     /gene="uppS"
                     /locus_tag="ACGI5H_002246"
                     /EC_number="2.5.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422884.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_process: GO:0009252 - peptidoglycan biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="polyprenyl diphosphate synthase"
                     /protein_id="HFG9697949.1"
                     /translation="MRIPKHVGIIPDGNRRWASQNGMTKDKGYESGIDPGLESYRLCR
                     DLGCEEVTFYGFTTDNTRRPSVQTKAFTKACIDAANILIDEGAALLVVGNTKSPMFPE
                     ELLPYTNRIKAKEGQIKANLLVNYGWYWDLNNISGVENVNKNNIQDYIQSFDVSRLDL
                     IIRWGGRRRLSGFLPVQSIYADFYVIDNYWPDFKSDDIKDAFSWYDTQDVTLGG"
     gene            29236..30060
                     /locus_tag="ACGI5H_002247"
     CDS             29236..30060
                     /locus_tag="ACGI5H_002247"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861670.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase"
                     /protein_id="HFG9697950.1"
                     /translation="MSKGNNNNNSRNKSKKTSHLNRKKRKLNKKKLAVLICFTVLFLF
                     IAFKATQGVVALVKSMDKSNKTNQQQNVNSEQFDLGNEEENKKKKYTVFIDPGHGGND
                     KGTESKTSNRYEKDLNLQIAKKLANKLSKQKDIQVVVSRTDDTYISLKDRAILANNSS
                     ADVLVSIHLNAEKNGNTATGIETWYRNKATDGSKELAQTVQSTIVSYVKVRDRGIVEN
                     NFEVLRESNMPAILIECGFLTTPSEEQKIINEKYQDQLAEGIVQGVLSYLDSKGNK"
BASE COUNT        11978 a         3298 c         5368 g         9579 t
ORIGIN      
        1 atttcaaata atgctgtaga ttctaaactt atgaatagta ggattaaatc aatagatata
       61 ataagagggc tatcaatagc cctcatgata gtctgcaata atcctgggac ttggatgaga
      121 atgtatcctc aattaagaca tgctgtatgg catggtgtaa cacttgcaga ttttgcattt
      181 cctttttttg ttatatcttt aggtgttaca attccaatat caataaatag taaactaaaa
      241 aataataaat ccacactgag tataatactt agtatattca agagaagtat cttattgata
      301 ttatttggat ttttcttaaa ttacctagga aatcctgatt tagatactgt aagaatactt
      361 ggagtacttc aacgtatggg attagtctat tttgtgacta gtttagtata tttactacta
      421 aaaaaattaa atgttggaag tactgctaca ataattactt ttctatgtat atctacattt
      481 ataatagttg ggtactacat attagcaaaa ccttatggat ttgagctaga aggttctctt
      541 gcacagttag tggatttaca tttcttcaag ggacatttgt acaagccgga atttgaacca
      601 gatggttttt taactagtat agtagcaatt tcttcaggta tgttgggatg cactatggga
      661 tgtgtacttt taaaagaaaa cataggagaa tataaaaaat tctttaaaat actggttatg
      721 agcataatcc tgctaatagg tgcttttatc tttaatcagt attttccatt taataaaaga
      781 ttatggtcta gctcatttgt acttttaatg gctggcagtt atggtatatt actgtcaata
      841 ttttatttta tatgcgacat caaaaataaa agtaaaatat ttaccccaat aatagcactt
      901 ggaagtagcc ctatttttac atatatgtgc cttgaaatat tgagtcatgt tttttggaat
      961 gttccaaaac ttacgaacaa agtcgattat ccaactacct tggtagagtg gactacatat
     1021 gaacttataa caccttgggc aggtacaact tgggattctc ttatattttc tttattgtat
     1081 gtcctattct gggttatagt aatgtctata atgtacaaga aaaaaatatt tattaaaatt
     1141 tagtgcaata tttttagatg ataaagtctt tgatttgttc aaatatacgg aaactatcaa
     1201 atataatcaa aatttctcct cgataaaatt taaaaaccat gccataaaag attacaaaaa
     1261 gtttacaatt tgtaattttt tgtgctataa tgaaaaaaga tttacataat attgaattta
     1321 tgtaatataa aacaagctta agatgtatta aaaaagattt aaagatttaa agaaccaaaa
     1381 aattaggggg gatatgatga aaaaaacaac aaaattattg gcaacaggaa tgttgtctgt
     1441 agcaatggtg gcaccaaatg tagctttagc ggctgaaaat actactgcaa atacagaatc
     1501 taattcagat attaatataa atttacaaag aaaaagtgta gtgttaggaa gtaaatctaa
     1561 tgcaagtgta aaatttaaag aaaaattaaa tgctgattca ataacattaa attttatgtg
     1621 ttatgatatg ccacttgaag ctactttaaa ttacaatgaa aagacagatt catatgaagg
     1681 tgtaataaac tataacaaag acccagaata cttaaatgta tgggaacttc aaagcataaa
     1741 aataaatggt aaagatgaac agaaagtttt aaacaaagaa gacttagagt ctatgggatt
     1801 aaatcttaag gattatgatg ttacacaaga gtttataata agtgatgcaa attcaacaaa
     1861 agcagtaaat gaatatatga gaaaaacttc tgcaccagta aaaaaacttg ctggagctac
     1921 tagatttgaa actgctgttg agataagcaa acaaggttgg aaagatgggt ctagtaaggt
     1981 tgtaatagtt aatggagaat tagcagcaga tggaattaca gctactccac ttgcatctac
     2041 atatgacgca ccaatattac ttgcaaataa agatgatata ccagaaagta caaaagcaga
     2101 gttaaaacgt ctaaatccaa gtgatgtaat aattataggt gatgatggtt cagtttcaca
     2161 aaaggcagtg tctcaaatta aatctgctgt aaatgtaaat gtgactcgta ttggtggagt
     2221 tgatagacat gaaacatctt tacttatagc aaaagaaata gataagtatc atgatgttaa
     2281 taaaatatac atagcaaatg gatatgctgg tgaatatgat gctcttaata tttcatcaaa
     2341 agctggtgaa gaccaacaac ctataatatt agctaataaa gattctgtac cacaaggtac
     2401 atataattgg ttatcctcac aaggtttaga agaagcttat tacataggtg gtagtcaaag
     2461 tttatcatca aaaattatag accaaatatc taaaatagca aaaaatggta cttcaaaaaa
     2521 tagagtttct ggagcagata gacatgaaac aaatgcaaat gtaattaaga ctttctatcc
     2581 agataaagag ttgagtgcaa tgttagttgc aaaatctgac ataatagttg attcaataac
     2641 agcaggacct ttagcagcta aattaaaagc tccaatactt ataactccaa aaacttatgt
     2701 ttctgcatac catagtacaa acttatcaga aaaaacagca gaaacagtat atcaaattgg
     2761 tgatggaatg aaagatagtg ttataaattc tatagcatct agtttatcaa aacacaatgc
     2821 accaacagaa ccagataatt caggttcagc agcaggaaaa actgtagtga tagacccagg
     2881 tcatgggggt tctgattcag gggcaacaag tggattaaat ggtggagcac aagaaaagaa
     2941 atatactctt aatacagcat tagcaactac tgaatattta cgttcaaaag gtataaatgt
     3001 tgttatgact agagatacag ataaaacaat ggctttagga gaaagaacag cattatcaaa
     3061 tactataaag ccagatttat ttacaagtat acattacaat gcgtctaatg gatctggtaa
     3121 tggtgtggaa atttattaca aagtaaaaga taaaaatggt ggaacaacta agactgcagc
     3181 atcaaatatc ttaaaaagaa tactagaaaa atttaatatg aaaaatagag gaatcaagac
     3241 aagaacactt gataatggaa aagattacct atatgtgtta agaaataata attatccagc
     3301 aatacttgtt gaatgtgcat ttattgacaa taagagcgat atggataagt taaatactgc
     3361 agaaaaagta aaaacaatgg gaactcaaat tggaatagga atagaagata cagtaaaata
     3421 aaatagaaaa tattaaagca aaacatatca tctcctgtta taatgtaaaa tataacaaga
     3481 gatgatatat ttttgtaaag aatcaaattg tttacaatga tgtttcttgt attgataatc
     3541 tgctcattat tgagtataat atagaaataa gtcaaaaata agatagaaat aagttgaaat
     3601 taagaattaa aaaaattttt attccaatat ggaggtaact atgtctggat atactaatga
     3661 tgagtgtgaa atacctaaaa ttaaaagcta tccaggggca gataaagaaa ttgcaagtga
     3721 gattgactat agcatagtaa aaggaacagt tttattcgac ttgtaccaaa gaattatgga
     3781 tttagtttta tctataatag gacttgtgat aggtttacct ttaatagcaa tatttggaat
     3841 tcttattaaa atagaggaca aaggaccaat aacttataag caagaaagac taggaaaatg
     3901 cgggagaaga ttctatatat ataaattgag atctatgaga acagacgcag aaaaatttgg
     3961 cgcacaatgg gctgaaaaag atgatcctag aataactaag gttggaaagt ttattaggaa
     4021 aactagaatt gatgagattc cacagctgtt taatatatta aagggggaca tgggcttaat
     4081 aggtcctaga ccagagagac cgaactttac tgttcaattt aatgaggaaa tacctggatt
     4141 tatcaacagg ctcgctataa aacctgggct tacaggttgg gcacaagtaa atggtggata
     4201 cgaaatcact cctgaagaaa aacttaaaga agatatttac tatataaaaa ataggagtat
     4261 attacttgac tttaagatac tctttaaaac tgttaaagta gtattgacag gagacggagc
     4321 tagataattt taaaatatta gattactaat caatgaaaaa gctctttaaa aagagctttt
     4381 ttattgtcaa aaaatacaaa aaagaaaagg aatgagaact tatgattaaa aaaatttcta
     4441 ctatattatc gttagttttg ttaatctcta tttctagtac gataggagta tttgcagatg
     4501 caaatcccaa aagagaattg atagaaggga gtataccaga gatttcgaca gaattaaata
     4561 aaagagcatt taaggattct aaagaagtaa ttcttgtaaa tgaagagtca attgtagata
     4621 gtataagtgc aacaccttta gcatatgcaa aaaatgctcc aatagttgta actaagagta
     4681 aaaatcttgg tagagtaaca agaaattatc taaaagaact aggtccagag aaggttacga
     4741 tagtaggtgg tttaaaggca gtatctaaag atgctgaacg taatatagaa aaaatgggaa
     4801 tgaaagtaga aagaataaga gggaaagaca gatatgatac atctttaaag atagctagag
     4861 aaatgtatag aacagtagga tttgatgaag catttttact tagctcaaca acaggattag
     4921 agaacgccat atctgtatat tcttatgccg ctaaaagtgg aatgccaata atatgggcta
     4981 aagatgaagg gtttgaggaa caaattgatt tcttaaaagg caaaaatctt aaaaaaatat
     5041 atgcattagg tgattcaaaa gagtttattg cagagattga ttctaactta aaaaatatag
     5101 aaggaataaa gcaaataaat aagtcaagta caaatgttga tttaataaag aagttttatg
     5161 atgaaaaaga tataaagaaa atctatactg ctagattaga ctttggtagt agatctgatg
     5221 taaacgaata tatttctttg ggagtagtat cagcaaaaga aaatatgcca atactgattt
     5281 gtagtgataa cttaagtcgt gcacaagata aattcttgaa agatagcaat ataaatgatg
     5341 tagttgaagt tgggtataca gtaggtgatt atagtctatt taagagcata tttaatctaa
     5401 cattcttatc ttgtatagta ttaatactat tattactatt gattacattt agggcactta
     5461 gatatgagtc gaaatagttt ttgatttata aggaagcttt tcataggtta aatttactta
     5521 attagaataa tgtttataag cagttttaaa agttctactt ttagagttta aattagataa
     5581 ggagaaagaa gatgtcaaaa acagctaaag cagcattgtg gattatggca gccactatgt
     5641 tttcaaaagt attaggtttc cttagagaac ttgtacttgc aaatttctat gggacaggta
     5701 tgtatgcaga cgtatttgta ttaacattaa atatacctgg tttaatcata gcagtcatag
     5761 gctctgcagt tgctacaact tatataccta tgtactttga gacaaagaaa agactcggag
     5821 atgaaggtgc cttaaaattt actaataatg ttttaaatat atgctatata atggctatag
     5881 taatagctat tattggtctt ttatttacag agcaatttgt tacagtattt gcagcaggat
     5941 ttagaaacga ccctgctaag ttccaagcag caatattatt tactaaaata atgatttcag
     6001 gagttttatt cctgagtgga agtaagatat ttagttcgtt tttacaggtg aatgacagtt
     6061 ttgtaattcc tgggcttata ggaatcccat ataatattat aataatagca gcaatagcac
     6121 taagtgcagg taaaaatgta tggatactgc cagcaggagc actattggct atggcaagtc
     6181 agctattgtt tcaactgcca tttgcgttta agaagtccta caagtataag ccatatataa
     6241 atttaaagga tgagtccata aaagagttag tcaacctagt attgcctatg ttggtaggag
     6301 tagctgttgg acagttaaat atatttgttg accgattatt ggcaaccact ttgggtgatg
     6361 gaaagttgtc tgctcttaac tatgcaaata ggctaaatga gtttgttatg gcattatttg
     6421 ttacatctat aataacagtt atatatccta aactagcaaa aatgtctggt aaagataata
     6481 aagaaggatt tataagtact attgtaaaat cttcaaattg tattatattg gtggtgcttc
     6541 ctatatctat aggagctatt atattagcag agcctcttgt tagaatatta ttccaaaggg
     6601 gtaaatttga tgcgttatca acagacctta catctatagc gcttagatta tattcactag
     6661 gtttattggc ttgtggagta agagatgtct tatatagggc attttactct ctttcagata
     6721 caaaaacgcc aatgataaat ggaagtatag ctttaataat aaatatagtt cttaatttaa
     6781 tattgataag accattgggt catgcaggta ttgctatatc aactagtaca tcaaacataa
     6841 ttacagttat attattattt atatctctta aaaagaaaaa tggatatttt ggaggggata
     6901 aaattataaa gactggtcta aaaagtttgg tagcatctgg tgtgatggca gtagctactt
     6961 tattgatata taataatcta tatgcattta tgggttcagg aacaattaaa gaaattatat
     7021 cagttggagc tggagtatta ggtggagctt ctgtatatac tgtattgata gttttattta
     7081 aggtagaaga gatggattta gcttttgaat ttttaagaaa aggaaaacaa aaactactta
     7141 gaagatagat aattaccttg aaattttaaa ttagagtcag aaaggatgaa aatatggatt
     7201 ataagaataa ttatgagatg tggttaaatt ctccttattt tgatgaacaa acgaaaaatg
     7261 agctattaag tataaaagat gatgaaaaag aaatacaaga tagattttat aaaaatttag
     7321 agtttggaac aggtggttta agaggtataa taggagcggg aactaataga atcaatattt
     7381 atactgttag acgtgcgaca ctgggcgttt taaattatat catgaaaact caaggagaag
     7441 aaggtaagca aaagggaata gttatagcac atgatagtag atacatgtct agggagtttt
     7501 gtatagaagt agcaaagact ttaagtgctt atggtgtaaa ggcttatatt tttgaagaat
     7561 taaagcctac accagaactt tcttttgctg ttagatattt aaagtgtgct atgggaatag
     7621 taataacagc aagtcataat cctaaagaat acaatggata taaagtatat gactcagatg
     7681 gtggtcaaat ctgtatagat atggcaaatg atataatagc agaagttaat aagattgatg
     7741 attacagtac tattaaaagt atagattttg aagaagcttt atctaaaaat ttaataacta
     7801 tattagataa tgaagtagat gatgagttta taaaagctgt taagaagcaa gttttaagac
     7861 aaaatataat agatgaatac gggaaaaaat taaaaataat atatacacct attcatggta
     7921 caggaaataa gccagtaaga aaagtcttaa atgaatgtgg ctttgaaaat gtaatggtag
     7981 ttaaggagca agaattgcca gattctaatt tttcaacagt aaagtatcct aatcctgaag
     8041 aaaagtcagt gtttaatata gctattgaaa tggcaaagaa caatggcact gatttgataa
     8101 taggaacaga ccctgattgt gatagagtag gtatcgttgt aaaagattca agtggtgaat
     8161 atgtagtctt aaatggaaat caagtcggtt cacttttagt tagatatata ttagagagtt
     8221 tagttgaaga aaataaactt cctaaaaaca atcctacaat aataaaaact atagttacat
     8281 cagaactagg tgcaaaaata gcaaaggctt ataatgtaga ttgtttaaat actttaacag
     8341 gatttaaatt tataggagaa aaaataaaag cgtttgaaga aagcaatgat agaagtttta
     8401 taatgggata tgaggaaagc tatggttact taattggaac tcatgctaga gataaagatg
     8461 gtgttgtatc ttcacttatg atatgtgaaa tggcagcata ctattcttca aaaggtatga
     8521 acttgtatga agctttgata gatacatata ataaatttgg atactacaaa gaggacttaa
     8581 agtcagtaac tttaaaaggc atagatggaa taaaaaaaat aaaagagatg atgctttact
     8641 ttagaagtgt taaaatagat aatgtggctg atgtaaaagt agataaaatt ttagactata
     8701 aagatggtgt tgatgattta cctaagtcag atgtacttaa atttttactt gaagatggct
     8761 cttggatagc tataagacct tcaggtacag aacctaaaat taaattttac tttggagcaa
     8821 attcagacaa tcaagaagat gtagaattta agttgaacaa tttaatatct tatatattaa
     8881 atgtagtgga ttctatataa aaagctaagg ggagataaat aatgaaagta tacaatgtca
     8941 taatggctgg aggaggagga actcgtttct ggccacttag tagacaagaa gtacctaaac
     9001 agcttataaa tttaagtgga gaagatgctt taataaacga aactataaac agaatagatt
     9061 ctctagcaaa aaaagatgat ttatttatag taaccaatga gaagcaattg gaagctttaa
     9121 aggatatagt aaaagataaa tgtttggata gtaatatatt gccagagcca tgtgccagaa
     9181 atacagcagc agctataggt tttgcagcat ttaacataat gaaaaaatat ggtgatggtg
     9241 ttatgtgtgt atatccagct gaccattata taaaagatga aaaagaattt aaatctattt
     9301 tggaaaaagc tatctatata gcagaaaata atgataaact agtaactatt gggataactc
     9361 ctacatttcc atcaacagga tatggataca taaattttaa tagagaaaat actatagaag
     9421 atgttgcata tgaggtagtg gagtttgtag aaaaaccaaa ctatgaaatt gctaaagaat
     9481 atgtaaactc taaaaagtat gtatggaata gtggaatgtt cgtatggaag gtatctaaaa
     9541 tactagaaga ttttaagaga tacttgccaa aagtatatga aaaattagaa gatataagta
     9601 aatacttagg aacaaaagaa gaaatggaaa aaataaaaga aatataccca actatacaat
     9661 caatctctat agattatggt attatggaaa gaagtaatga tgttatagta gttcctggtg
     9721 attttggatg gaatgatgtt ggttcttggg attctctagg tgcaatatat ccaactgatg
     9781 atgaaggtaa tatcaaaaga ggtgaaaata ttactataga tactaaaaat tcaattatat
     9841 attcagatga caaattaata tcaacaatag gtattagtga tttgatagta gtatctacaa
     9901 atgatgcagt tatggtttgt agaaaagata aagctcaaga tgtcaaaaaa atagtagagc
     9961 agttaaaaga agaagataga caagaatata tgtaggaggt gttcatttga ttcctaaaaa
    10021 aatacattat gtatggtttg gtggtccaaa aggaaatata gaaaatatat gtataaattc
    10081 ttggaaagaa aagcttccag aatatgagat agtagagtgg aatgaaaaaa actttgatat
    10141 agagaaagaa ataaaaggaa ataagttttt ggaagaatgt tataaaagaa aactttgggc
    10201 attcatatct gattatacaa gaataaaagt actctatgaa caaggtggag tttatatgga
    10261 tacagatatg caaatattaa aggatataac tcctctttta gaaaataata ggctaatctg
    10321 tgggtatgaa gatgatagag agtatataaa tggtgctata ataggtgtag aaaaaggaca
    10381 tcctttttta aaagacttat tggagtatta tgaaaaagaa gtacttactt cttcattgtt
    10441 tacaatacca aagataatga ctcatcttat ggaaaagaat tataagaaga ttgacccaaa
    10501 taattatgaa gaaggaatac gtgtttacga caaagaatat ttttatcctt ttggatttaa
    10561 agaagacttt acaccagaat gtataacaga aaacactttt gggatacatt ggtggggaaa
    10621 aagttgggct aaaaagagaa attatttctt agaaagcaaa cacttaacag gtgtaaataa
    10681 gatatggaag tgttgtaaaa tatttgcaag taatacttta cgaagctaaa agggagaaag
    10741 taaaatgaag actttaaatg atgatagaaa tattatgatt agaaaatatc tttatatatt
    10801 tgttttgttt atcatattac ttagaaagta tatgatatca tttattgacc caaatatgga
    10861 tatagggatg attaaatcag cgttatttta ttcttcaata ggaatactaa tgctactttt
    10921 tttatttgac aagagaaaaa gtataacaga aatggtacta gttggagttt gtgtcttact
    10981 ttatttatta aatagggaag gagctatatt attaatcgtt ttattagctg tatcagctaa
    11041 gcaaatagat gataaattta tagttaaaaa ttatttaata atatcagcat gttttttaat
    11101 ggtagctata ttattattta atctatttcc ttcattgata tttaatcagg aagtccacta
    11161 tagatatata gaaaaaatag atatgcttgt tacaagaatg gattttggac ttggtaatcc
    11221 aaatagtgta ttttatcata tggttactat atatgcagca tatatattct taagatataa
    11281 agattataat aaatgggata gaataatttt atttggttct gcattttttg tttatcaaac
    11341 cacatatagt agaactggat ttttcactat attagcagga ttaatatttg tagaaataat
    11401 aagatggata gatataaaaa aaataaaagg actaccaatg ctcctaaaga cattaccgat
    11461 aatacttact ttatttagtg taattattgg tacagtattt gataaaagca ctttattaaa
    11521 tagattatta gcaagtagac ctaagttctg gcatgtatac ttggctgaaa aggggaattt
    11581 tctaaaacct tttggaaatt catatagtcc tgctataaaa gcaactaatc cattagatag
    11641 ttcttatgta tatataatta gtgtactagg agtagttgct tgtatattat ttatgtattt
    11701 gatgtataaa ggaatagaaa gctttataga aaaagataaa aaagcatatt tagtagcttt
    11761 atttatattt ttactatact cttttgcaga aaatttatta ttagaagctt catttagttt
    11821 tgcagtagta ttactaataa aagaagtgat attaaatgat aaaagggaaa tagatttgtg
    11881 gaagatgaaa agtaggaggt agtaatgtta atatcattaa taatgccaac attaaataga
    11941 tatgatgata tatacttact tatggacagc ttagaaaatc aaacttacaa aaactttgaa
    12001 cttatagtag tagaccaaaa tgataatagc aaagttaaag aaatagttga taaatacatt
    12061 gataagttag atataaagta tataaaaagc tctaaaaaag gattgagtta taacagaaat
    12121 gtaggcatag acaatgctgt agggcaaatt ataggtttcc ctgatgatga ttgtgtctac
    12181 gaaaatgata cattagaaaa agttataaat ttctttaata aaaataaaga ttataaaata
    12241 tacagttgca aaactatgga ttcaaataaa gttgatgcat ttaagaaaat gtatgatgga
    12301 acttgtgata tcacaagttc caacgttttg gatactataa catccataac tttttttatt
    12361 gattttgaag gtaaagacta tacaagattt gatgagaaat tgggtgttgg tggagagttt
    12421 ggtgctggtg aagagataga ttatgtttta aacttattga gtttaggttt taaaggaaaa
    12481 tactttggaa atgatataat ttaccatcct gcaaaaaaac attctaaatc taaagaaaag
    12541 tatcaaaaag attataacta tggaagaggc tttggagcgc tttgcaaaaa ggaaatagtc
    12601 tatagaaaaa attataagtt tgcaaaagtt atggtatcaa aacttgtaag aaatatagga
    12661 ggtcttatat tgagttccaa tagagattat catagtgcca ctataaaagg aagaattaat
    12721 ggatttagac agtacaagtt ataatgagga tggtgtttat ggacaaggtt aaatttttaa
    12781 taaatatgct tttggctttt tttatatatc catttaataa gcataagttt aatggtagag
    12841 atatctggct tataggtgga cattcagggg atatatacaa tgataattca aagttttttt
    12901 atgagtatat gctaaaagaa cataatgatg tagaaactta ttgggtagta aataaagaca
    12961 gtaaagtatt tgataaaatt ccaggcaaaa aattaataag aggaagtgta gaaaactatc
    13021 tgtattatta caattcaaaa gctatagtat tttcacatgc accatcagca gatatagcac
    13081 catacaattt tgctgtacct gttcttaatt attttcataa aaaaacgata aaagtgtttt
    13141 taaatcatgg gactataagt tttaaaaaaa gaaaacctat gaacaaaaag ttcaaaaata
    13201 ttatagataa cctatataaa agctataata tagttacagc aagttctgaa tttgaaagaa
    13261 atgttatggt aaatgattgg ggaatgttag atgactcagt ttatataatt ggaaatgcaa
    13321 gatatgacaa tttaccaaca aatgaagttg cacaaactcg agatatatta tatactccta
    13381 catggagaga ttggataaaa tttagttcag gaaaatttac ggatacagat tattttaaaa
    13441 atataatgaa ttttttaaat gatgacaaat taaataaaat attagatgag aaagatataa
    13501 atgtaaaaat ttatatgcat catcttatgc atgagtttat agatgatata aaagaaaata
    13561 taacaggaaa acgaattgtg tttttagata aaggggtaac tctagcaaat gaaatcagaa
    13621 aatcagctgc aaatataact gattattcaa gtgtagccat agactttttg tatatgaata
    13681 gacctatttt gttttaccaa ttcgatttgg atgaatatat ggaaaaagtt gattcatata
    13741 tagatttaaa aagtgaaatg tttgggtctt tggcttataa taatgatgaa gccgtgaata
    13801 aacttattga tattattgaa aataattttg aggttatgga taaccaaaaa aatgaaagaa
    13861 ataagttttt cagatataat gataataaga actgcaagag gatatatgat tgtgtattaa
    13921 gtaaaattaa ataaatattt tataaatgat gaggaaggta atatgaagaa gaatttagta
    13981 tctataatta ctcccatgta taattctgaa aaatttattg aagcaaccat aaaatcagta
    14041 ttaaaccaaa cttatcaaga atgggaaatg ttaattattg atgattgctc aacagataat
    14101 agtcctaata tagtcaaatc ttatatgcaa caggatagta gaataaaatg tataaagact
    14161 gagactaata agggtgtctc taatgctaga aatttagcac taagtaaggc aacaggacaa
    14221 tttatagctt ttttagatag tgatgaccaa tggaatagta gtaagttaga aaaacaagta
    14281 aattttatgt tagaaaatga ctatgtaatt tcatttactt catatgaact gatggatgaa
    14341 aatgataaaa aattaaacaa agtaataaaa gttccaccta atgtagatta tagaagatta
    14401 ttaaaaggaa atatcttagg atgtcttact gttgtgattg ataagtctaa attggatttt
    14461 gaaataagaa tgagtggtgt aagacatgaa gattatgttt tatggttatc gatattgaaa
    14521 aaagggcata ttgctcatgg aataaatgaa gttctagcat tatatagaaa atctagtaat
    14581 tccctaagtg gtaataaaat aaaagctgct atgtggactt ggaatatata tagaaatata
    14641 gaaaaaatac ctttatacaa agctatatac tactttatta attatggaat aaacggaatc
    14701 aaaaaaagtt agacagagag gaagatttaa ttaatgtata aatataaatt tactgtattt
    14761 actccgacgt ataacagagc tcatttactt gaaaatttgt acaatgattt aaaagctcaa
    14821 acttatgatt tcaatgattt tgaatggttg attgttgatg atggaagtag cgacagtact
    14881 aaagagttag ttgaaaaatt tatatcagaa aataaattaa atataagata tatatacaaa
    14941 gaaaatggag gaaaacatac tgcaataaat ctaggtgtaa aaaatgcaga tggagagcta
    15001 tttttcattg tagatagtga tgatggttta attaaagatt ctcttgaaat tgctaatgat
    15061 gagtgggatt ctttagagaa taaagaagga tttagtggag ttgttggact ttgtgtatat
    15121 ccaagtggag atttgatagg gacagaaatg cctgaagata agaaaatatg tcactttgca
    15181 gacctatatt ttaagtatgg cgttaaggga gataaaagca tagtatttgt aactgatgag
    15241 cttataaaat ttccttttcc agaaagaaaa gaagtgagat ttttaccaga aagtgtagta
    15301 tggaatgaaa tgtctaaata ctataaagtt atatgtgtaa ataaacctat gataataaga
    15361 gattatttgg atgatggttt gactaagaat atattaagta aaaatgcatt aagaggtaga
    15421 gcattagagt ttttatattt aataaatcaa aatacatatc cattaagtag atatccatat
    15481 atgtggataa aaaattacat aaatttagcc agatactcat tgttgtctga tagtcattat
    15541 tttggtgaat taagaaaagt atctgataaa ttgttgtatt tagcattatt cccattagga
    15601 tattacaaat atattggaca aagaaaatta gtatctaagt aaacttgttg gtatagtact
    15661 gctagttgct atataaggag agtaaaaata tgaatgagcc tttagtatcg ataattactc
    15721 ctgtttataa ttcagaagag tttttatcag agacgataaa gtcaatccaa aatcaaactt
    15781 ataaaaattg gcagctttta ttagtggatg attgttctaa ggacaattca agtgaaatta
    15841 taaaaagttt tcgaaaagaa gatgctagaa taaaatatat aaagcttgaa aaaaattctg
    15901 gagctgcagt atctagaaat gttggtatta agaatgcgga aggtcgattt attgcatttg
    15961 tagatagtga tgatttatgg gatagtagaa aattagagat tcagatagaa tatatgttaa
    16021 aagaaaatgt aggtttttct tttacatctt atagatatat gagacaagat gggtcaaaaa
    16081 cgaataaggt tgcaagagct cctaagaaaa ttgactatga aggattactt agaaatacta
    16141 taataggatg ttctacagtg gtcattgata aggagattgt aggagagttc agcatgcctt
    16201 tggtaagaag aggacaagat actgcaacct ggttacagtt acttaaaaag gaaaaatatg
    16261 catatgggat tcaagaagat ttagtgaatt acagattagt tggaaattct atatcaagta
    16321 acaagataaa agcattaaaa cgaacttgga atacttatag aaatgttgaa aatttaagtt
    16381 taccaaaaag tctatatgta ttttgtttct atgtttttaa tgccattaaa aaaagagtat
    16441 aagttttata tacttggagg taaaaaaatg aaaatagcta tagctgggac gggatatgta
    16501 ggtttggtta caggtgtttg tctagcagag gtaggcaatg aaaatgtagt ctgtgttgat
    16561 gtagatgaac aaaaagttaa atcaatgaaa cttggaatag cacctatata tgaagaaggc
    16621 ctagaagaac ttatggttaa aaattacaac agaggaagaa tagattacac tacagactat
    16681 aaaaaagctt atgaagatgt agatgtaata ttaatagctg taggtacacc tgagagaagt
    16741 gatggttcag ccaacctaga ttatataaag gcagttgcaa agcaaatagc tgaaactgtg
    16801 acaaaagata ctctagtagt aataaaatct acagttccaa ttggtacaaa tgaagagata
    16861 gaagattata taaatagaaa cctaaaaaat gatgtaaaag tagaacttgc atctaatcca
    16921 gagtttttat cacaaggaac agcagtaaaa gatactctac atgcttcaag aatcgttata
    16981 ggtgtagaaa gtgaatgggc tagagaaata ttagaggaaa tctataagcc ttttaatcaa
    17041 cctataatag ttacaaatag aaatagtgct gagatgataa aatacgcatc aaataacttc
    17101 ttagctctta aaatatcatt tatgaatgat attgcaaatc tttgtgaaat agcaggagct
    17161 aacatagaag atgtagcttt aggaatgagt tatgatgata gaataggaag taagttttta
    17221 aaggcgggaa taggatatgg tggttcttgc tttccaaaag acacaaaagc tcttcactgg
    17281 ttatctgaac ataatggtta tgaattaaaa acagtaaaag ctgcaataga agttaatgaa
    17341 agtcaaaaac ttaaattagt tagaaaggca tctaagttag tagagagctt tcaagatatg
    17401 aaggttgctg ttttaggttt gacttttaag ccagacactg atgatataag agaagcacca
    17461 tctataccaa atataaaata tttgctcgaa agaggggcaa gagttactgt atacgaccca
    17521 attggtgtaa ataatactaa gaaaatattt ggtgactcta tactttatgc tgattctgta
    17581 gatgatgcga tagaagatgc agagatatgt tttataatga cagaatggaa agatgtatta
    17641 aattatgata tacataagta taaggaaaag atgaaaaatc ctttagtcct tgatggaaga
    17701 aattgttata aaattaaaga tatggaagag ttaggaattg agtattattc gataggaagg
    17761 taaatattat gaagactgtt tgttatttag ctgatgggtc aaatcctcat actttaaaat
    17821 ggtgtagttt ttttaaaaat aaaggatatg acattcatgt aatctcttta aatggaggtc
    17881 acatggaagg aataaaaatt tataattttg gttctaatgt agaagaacta aaaaatgaaa
    17941 atatttctaa aaaaacggga tacttaggtt caataaagca gataaagaag ctagtaaatg
    18001 aaataaagcc agatatattg catgcacagt atgcaagtag ttatggattt ataggaagtc
    18061 tacttgggta tcatccatat attatttctg tttggggtac tgatatttat gatttcccta
    18121 ataatggttt tatacaaaaa caaattataa aacataactt tagaaaagca gactatatct
    18181 tttcaaatag tagagatatg gctaaagagg ctaataaata tacagctaaa catgtagatg
    18241 taaccttttt tggagtagat atggataggt ttaagcctat ggaagtagaa aaagaagacg
    18301 cttttgtaat aggaattata aagagtttag aaaaaaaata tggaatagaa tatttaatac
    18361 aagcatttaa gatgcttaaa gatgaatata aagataagaa aataattctt aaaataggtg
    18421 gctctggaag tcagatggac aacctaataa atttagctaa agaattgggt atagaaaatg
    18481 atgttcagtt tttaggaaga atatctccag aaaatgtaag caagactttt aattcttttg
    18541 atgtaactgt atttccttct ttaagagagg gatttggagt ggcagctata gaatcagaag
    18601 catgtgaagt acctgttata gttacaaatg taggaggaca tccagaatct gtatgggaaa
    18661 atgaaactgg cttaattgta gaaccaaaac aaccagaaga aataaaaaat gctataataa
    18721 aactaatgga aaatgatgaa cttagactta atatgggtaa gaaagggcgt caatttgtta
    18781 gagaaaatta tgaggttaat ttaaacttta atgatataga aaaaatttat gattctatat
    18841 ttgataaata taaaaaataa aatgaaaaaa tacagcaaaa gatagatgtt gttggctatg
    18901 cttaggtgcg tagcttttgc tgtttaaagg agggcttcta gttatgcgag aaagtataga
    18961 tttagagaaa gaaagctttt ttaataggct ttttaaaaaa tataaattta gacatttaac
    19021 actattaatt ctagatattt gtagcgtact agtagcgttt cgaatgtctt taagcttgac
    19081 aggtaattta aatgcattta ccactaatga tataataatt tcagcgtgta tatatatagt
    19141 acttcatata gtatcattta gattgtttaa gtgctacaac acattatgga gatatgcagg
    19201 agaagaagaa attatatcta tttttgtggc aactttagct tatttaattc cgatttatat
    19261 aataaataaa ttattagggt ttgattatcc tataatgttt tatgtattaa atacaatatt
    19321 tattataatg tttacaagtg gcgcaagaat agcctataga gctataagaa tagtcatgaa
    19381 caagacatat tctagaggaa aggtttcaaa tatccttata attggtgcag gagatgcagg
    19441 agaaatggtt atacaggaac taaaaagaaa tccagaactt aaaaaagtag cagtggctat
    19501 aattgatgat gataaaaata aaattggaag aataatccac aatgtgaaaa ttgtaggaac
    19561 aacttcagat ataaaagatg tggtagaaaa gtacaatgta gatgagataa tcttttcaat
    19621 agcaaacata gagaaacgta gaaaaaaaga gattattgat atatgtaaaa acactaactg
    19681 taaaataaag acaataccag gaatttacga aattatagat ggaaaagttg atataaaaca
    19741 gattagagaa gtagagatag aagacttgtt gggtagagag cctataaaaa caaatttaag
    19801 agagataagt aattacattg agggaaaagt aatcctaata actggaggag gaggctcaat
    19861 tggttcagag ctttgcagac agattgcagg atttaatcct aaagagctta ttatagttga
    19921 taattatgaa aataatgctt actcaataca acaagaattg cttagaaaat ataaaaataa
    19981 attagattta aaaacagtaa tagcatcaat aagagaagaa aaaagaatgg atgaaatatt
    20041 taataaatat aaaccagaag tggtatttca tgcagcagca cataaacatg ttcctcttat
    20101 ggaatcgagc cctggcgaag ctataaagaa taatatattt ggaactttaa acatagctgg
    20161 cttgtcttca aaatatagag ctaagaaatt tgtccttata tctacagata aggctgtaaa
    20221 ccctactaac ataatgggag ctactaaaag agctgctgaa atgattatac agactatgaa
    20281 tgctgaaagc cagactgaat ttgttgctgt tagatttgga aatgtgcttg gtagtaatgg
    20341 tagtgtaatt ccacttttta agaagcaaat tgaagatggc ggaccagtga cagttactca
    20401 tccagatatt attagatatt ttatgacaat accagaagca gtaggcttag ttatacaagc
    20461 tggggctatg gctaaaggtg gagaaatatt tgtacttgat atgggagaac ctgtaagaat
    20521 attggattta gcaaaaaact taattaaatt cagtggattt gagccagatg ttgatataaa
    20581 aattgaattt tctggtctta gaccaggaga aaagttgtat gaagaactac ttatgtcaga
    20641 agaaggtctg ttggatacag agcataaaaa gatttttatt ggtagaccaa tagatgttga
    20701 tagagaaaaa ataacaaaat acttaaaact tttaagagaa attactaaca atgaagaggt
    20761 tgaaaaaata gatggtatta tgagggaatt agtgccaact tatattaaac cagaagatgc
    20821 taatatcaaa gaaattgcaa caactagaga aaagtagaat atatttctaa tttgtaacca
    20881 gggggagcaa aaagaaacaa atatatacta aaaagaaaca aaagattaca aaaagattac
    20941 aaaaagatta caaaaaaggt tgcaatttat tttgatgtaa gatagaatgt taattaggaa
    21001 ttggaaacga aggaacaaaa tgttaaattt tcgaaaggat taggtatttg agattatgat
    21061 gaatattaaa aataaaaaac atatattgaa aaaatttata gctatggtgt taatagcagg
    21121 agttgtcaca gtagaagcag gagcaataac ggctagtgca gcagagccaa ctaattcacc
    21181 tatgagtgca acagtagacc agtgtgattt tttaaatgta agaagtggag ctagtgcaaa
    21241 tgatgcagta gtaggaaaga taaacacagg agacaaagtt gaagttttag aattacattc
    21301 aaatggatgg attaaaataa aaagtgttga caatgttaca ggatgggtaa atggagatta
    21361 tttaactatt caaggtggaa atgtagatgc aaaggtacaa aatgttttaa acttagcatt
    21421 taagcaacaa ggtaagccat ataaatgggg agcaactgga ccaaattctt ttgattgttc
    21481 tgggttcact tcttatgtct ataaaaatgg agcaggagtt aatttaccaa gagtatcaag
    21541 atcacaagca acagtaggaa agaaagtatc aagagcagaa ttaaaaccag gagatttagt
    21601 tttctttggt tcaggtggtt caataaatca cgttggattg tatgtaggag attctaaatt
    21661 catacattca ccacaaacag gagatgtagt aaaagttact agcatggctc caggaactaa
    21721 ttatgcaaga agacttataa ctgctacacg tgttttacaa taataataga tattgattta
    21781 cataggattg aatattaaca ttaaatatat aattacattt aatgttttac atagagattt
    21841 aagagtttag taatattaaa atagtgatga acgttataaa aacagcaaag aagataaatt
    21901 tctttgctgt tttttttata ataaattatt tcatattata atcaaatatc aaatataaat
    21961 tttaactata ttattcaata tttgacagat aatatgaatt ttagatatac ttaataagaa
    22021 gtatattgta gaaaaaataa atttaaaaaa ttaaggggga tgaaatgaaa aaaataagta
    22081 tattagtatt atcattgata atgacactta ctatgtgtag tgtaagttca tttgctgatt
    22141 catcaaatga taaggaaatg agagctgctt ggatatctac agtttataat ttagactggc
    22201 ctaagactaa gaataatgaa gccaagcaaa aaaaggaata cacagattta ttggacaaat
    22261 taaaaagtgt aggaataaat acagcagtgg ttcaagtaag accaaaatca gatgctttat
    22321 ataaatcaaa tataaaccca tggtctgaat atcttaccgg tacacaaggt aaagaccctg
    22381 gatatgaccc attaccattt ttaatagaag aagcacataa aagaggaatg gaatttcatg
    22441 catggtttaa tccatataga ataactatgg cagatgagag catagataaa ttgccagcaa
    22501 accatccagc aaagaaaaat ccaagctggg tagttaaaca tggaaataag tattactacg
    22561 acccaggttt accagaagtt agaaagtaca tagtggatag tatagcagaa gtagttcaaa
    22621 attacgatat agatggagtt cattttgatg attacttcta tccaggagta agtttcaatg
    22681 atactgcaac ataccaaaaa tatggaaaag gacaaaataa ggatgattgg agaagagaaa
    22741 atgtaaatac tctacttaga gatgtaaaag cgtctataaa gagtataaag cctaatgttg
    22801 tatttggtgt aagcccagca ggtatatgga gaaataagag tagtgaccca acaggttcag
    22861 atacatcagg taatgaaagt tatgtaggta catatgcaga tacaagagca tggataaaac
    22921 aaggattgat tgactatgta gttccacaac tttactggcc aattggtctt aaagcagcag
    22981 attattctaa attagtggca tggtgggcta atgaagtaaa aggaacaaat gtagacttat
    23041 acataggaca aggtatatat aagcaaggtc aatcgagtta tggtggacaa aatatagcaa
    23101 aagaaatagt acaacaagta acattaaata gaaagtatag tgaaataaaa ggtagtatgt
    23161 atttctcagc taaagatata gcaaatagta cttctataca aaaggattta aagagtttat
    23221 attctagtag tgaagaacca gttactccac catctaatgt taaagtggag aaattaagag
    23281 gcgacgaaag atatgacaca gcagtagcaa taagtaaaaa aggttgggct acaaattcag
    23341 atacagtagt attagtaaat gggtactcta tagttgatgg tataacatca acaccacttg
    23401 ctacatcaaa tgatgctcct atactattgg taaataagga taatatacct acatccacta
    23461 agaatgagtt aaaaagactt aatccaagta aagttatttt aattggagga aataactcta
    23521 ttggagataa agttgagagt gagataaaag atacattgtc aaatgtatca ataaatagag
    23581 ttggtggttc agatagatat agtacatctt taatgatagc aaaagaatta gtaaaaacta
    23641 atccagtaga aaaactatat ataacaagtg gtacaggtga agcagattct ctttctatag
    23701 cttcaaaagc aggagaagaa aagcaaccaa tagtattagt atcaaaagat aatgtaagtg
    23761 atgaagttta caattggata tcagatttga aagtaaaaga tgcttatttt ataggtggta
    23821 atctaagtat atctgattca gtaataaata agctggataa ggtcattaca aatgatgtat
    23881 ctaaaaatag aatagctgga gaaaatagag aagaaacaaa tggaaaagta atacaaaaat
    23941 tctatccaaa tgctgaatat tcatcaatgt ttgtaagtaa aagtaatcaa ttggtagatg
    24001 cattaacatc aggtccttta gcagctaaat taaaatcacc agtagttatg cttggaaata
    24061 gtgtaacatc tgctcagaaa actgctttag agcctaagaa aactactcta gtatacgaag
    24121 ctggagatgg tataaatcaa aacacattaa acactttctt aaacttagtt aagtaataaa
    24181 aaagttaatt taaaatacag agtattttat aaatgtagat taaaatgaaa attatcatga
    24241 taaattagaa aataaaaaag aactatatgc attttgtaat caagtgtaca cagcaacttg
    24301 aaaataatta tgcgatatag ttctttttta gtaattaatc ttatactttt taataaactt
    24361 tatgttgaat tttttattgt ttaaactcta tgtcattaaa tataaaatcg tgtaatatgt
    24421 ctaaagtatc tgggtcaaat ctaagaaccc atccagcttt tccatatata ccacctgtac
    24481 tatgaatttc atcatcaata ggaaattcaa attgcttaat atttaagtcg cccattttta
    24541 aaacttgagc tcctaaagaa agtattgcat taggcttcat gttagtttta acatatggaa
    24601 gaactgcatc taataaacct ggatatttag taacaggtaa agtttccgtt ttcttgatta
    24661 tagcttgtat aatctgtctc tgtctgccat ctctagcaaa ggctgtatcg ttgtgtctga
    24721 tacgtgcaaa agatagtgcc tgatatccat ttagagtctg ctttccagag tttctaatgt
    24781 attgtatgct acctttatca tcacttttat tccatttata agtttcagga ataaatttat
    24841 ttagttctcg tatttctcct ttttcaacag taacctcaac gccaccaata gcatcaatta
    24901 tatacataaa tgattcgaaa ttaacacaag cataattttg aatatcaata ttaaaattct
    24961 cttcaattgt ttgtattaat aaatcagctt gtccataagc ataagcatga gtaagttttt
    25021 gtttaccatg accagggatg tctacatagc tatcacgagc taatgatgta agtttgatat
    25081 cattgtgttt gttatcaata gtaagtatca tcatagcatc tgaccttgaa gaatcttcat
    25141 ttggtctagc atctgttccc ataagtagta tgttaattat cccatcttca tttttatggt
    25201 cattgttatc caataaatca ctacttatgc tcgagtcatg aatagcagat aatttataat
    25261 aaaaatatcc atagacactt atagggaata ttactaccaa gaaagccagt agtataacaa
    25321 atttctttaa ttttgacaaa agtacccctt ctttcttctt tttcctgtat attttttaat
    25381 agcatacact taattatatt aaagtattga gatatattca atacttgttt cagttacaaa
    25441 aaaaagacaa tgatataatt tataagaaaa tttatcgacc tatatatata gttaaaagta
    25501 tatataatat attttttaaa agtaatttat attttaaaat aaaaacacac cccataaata
    25561 caaagtaatt tgcatttaag aggtatgtat ttatcatcaa attattggtt tgttttggaa
    25621 tttctaatct tcaaccataa tatctttaaa tatgaaatca tgcattgcat ctagttcata
    25681 ttcctcaaaa ggtattacat agcctgcatt acctattttt ctaccatttt cagtagaaag
    25741 aggaaactcc atagatttca aatttaaatt tcctatactt aaaagttctt ttcctaaaga
    25801 tattatttca ttaggattca tattagtttt tacatacgga agtattgtgt taactagatt
    25861 aggatattta gtgactggta aatccttaac accatttatt aaactctgta taacacttct
    25921 ttgtcttcta tctctttcat ctgtactatc attttttctt atacgagaaa atgcaagtgt
    25981 ctgatatcca tttaattttt gctcaccaga atttcttata tatttaagag aacctttatt
    26041 gtcattttta ttccatttat aagtttcagg aataaattta tttaattctc ttatttcact
    26101 cttatcaaca gtaacagtaa ctccacctaa agcatcaact atatccataa aagagaaaaa
    26161 gtcaactacg gcgtagtttt gtatatcaag ttggaagttt tcttctatag tttctattaa
    26221 taagttagct tgtccatata cgtaggcatg tgttaatttt tgttctccac gtcctggtat
    26281 attaacataa gtatctctat ttaatgaagt tagcttaaga cttttatttt tattatcaat
    26341 agtaagtatc atcatggcat cagaacgaga aacttcttct cctggtcttg catctgtacc
    26401 taacaataat atgtttgtga tattttcttc gtttttatag tcattactac taagcgcctc
    26461 tgtatttata ctatcatctt gtatagtttt taatttagta aaaacatatc catatatact
    26521 aacaggaaat gctataacta aaagggctag aaatataacg aactttttga gtcctgacaa
    26581 taatatcccc tactttctaa attttttaat tacacatagt taattatatt aaaaatttgt
    26641 tacataagca ataaaaaaca caataaatta gcataagttt gtcataatat aattattttt
    26701 atagcatttt atagaagaaa gtgtgtagtt attattgatt ttattggaat ataattgtat
    26761 gaagacttaa atttttataa actgatgtgt atattgaaaa aaatattttc ctgaatgtag
    26821 ttatagcatc ttatgaaagg tgcaaattgt aatttaaaat ttttagtgta taataagaat
    26881 tgaaaattca aaccgataaa aattaataaa aaataattat aaattaataa tttgggggag
    26941 gaaatgtatg ataaaattaa tagcaacaga tttagatgga actttgttag atgaaaagag
    27001 cgaaataaat ccagagtttt ataaagtatt taaaaaatta agagagagag ggataatgtt
    27061 ttctgctgct agtggcaggc agtatcaaaa tcttataaaa aaatttgaag atataaaaga
    27121 tgatatgatg tttatatcag aaaatggaac actagtagta tataaaggaa aagaaatatt
    27181 atcaaatcct ttaaataaag aattagtaaa tgaaatcata gagacaacaa gaagtataaa
    27241 agggaaaaaa attgtaatga gtgggaaaaa atacgcttat atagaaagca aagatgaagc
    27301 gtttatacaa gaggtcagta cttattatgc aaagtttaaa attgtagaag atttgacgaa
    27361 agtagaagga gacatattga agatagctgt atttgacttc aaaggtgcag aacataataa
    27421 taatatctac tttgaaaagt tttctgatag agctcaagta tgtatttctg gagtggagtg
    27481 gcttgattta actgcaaaag gtgcaaataa agggagtgcc ataaaaaaag tacaaaaaat
    27541 gttagatata aaatatgaag aaactatggt atttggtgac cagttaaatg atgtggaaat
    27601 gatgaaaagt gcctatcata gttatgccat ggaaaatgca aatgaacatt tgaaacaaat
    27661 tgctagattt agagcaaaaa gaaatactga aaatggcgtt gtagataaga taaaagaggt
    27721 tataaaaatt ggatagtcat atgtatagat gaaaaagatt attttgaaga aatcaaaaaa
    27781 atatcaatgt aattttgata aataagttta tttatgcgaa aattacattg atatttaata
    27841 aacatcaata atagatattt atttttttat gatattcagt attttgtttt ctatttgagt
    27901 tgcattttca gcagaaatta aataaacata tctacctgcc ttctcaatta tagtattatt
    27961 tgctatttca gaattgattt tttctccatg tccttctcca aaaggtgctt gtatcatatc
    28021 ttttttataa ttttctagag ttttatagat tttatctacc tcgtcagttt ttataacgat
    28081 aatatcttct agagataatt tttcagaaga attaattaca aaaccttgaa ttatgtcttc
    28141 ctctacatca ttaaaatagt taaaatcctt tgcatcaaag atttttgatt cctttataag
    28201 taaatcagaa gattttaatg ctttttttat ttttgatgta gaaacgtttt tgtaatcacc
    28261 acttgaagaa caactaacca ttcctaatga taagattatc gaaaaaaaca atattaaaat
    28321 ttttttcatg ataaacctcc aagtttttta aactctgtct taaattagtt tactacataa
    28381 ttatataaaa ataaatgtat ttaatgttac agttttgatt aataatgtaa tattttgata
    28441 ataataccta ttgagaggtg attagaaatg agaataccaa aacatgtagg aattataccg
    28501 gatggaaata gaaggtgggc aagtcaaaat ggtatgacaa aagataaagg atatgaaagt
    28561 ggaatagacc ctggactaga gtcttataga ttatgtagag atttaggctg tgaagaggtg
    28621 actttttatg gatttacaac tgataataca agacgtccat cagtgcagac aaaagctttt
    28681 acaaaagcat gtattgatgc tgcaaatata ttaatagatg aaggtgctgc tttattagtt
    28741 gtaggaaata caaaatctcc aatgtttcca gaagaattat taccatatac taatagaatt
    28801 aaagccaaag aaggtcaaat aaaagcaaat cttctggtaa attatggttg gtattgggac
    28861 ttaaataata tatcaggagt agaaaatgta aataaaaata atatacagga ttacatacag
    28921 tcatttgatg tatccagact agacttgata atcagatggg gtggaagaag gagattaagt
    28981 ggtttccttc ctgtacaatc aatttatgca gatttttatg ttatagataa ttattggcca
    29041 gattttaaga gtgacgatat aaaggacgca tttagttggt atgatacaca agatgtcact
    29101 ttaggtggat aattaaaaat attctgattt aaggttgtag agtgttttaa attattgaaa
    29161 aaaaaacttc ttgatggtaa aataacacta ataatatgta aaagtgtaaa aatttatacc
    29221 aagaagggtg aagaaatgtc aaaaggcaat aataacaata attcaagaaa caaatctaaa
    29281 aagaccagtc atctgaatag aaaaaagcga aaattaaata agaaaaagtt agcagtgttg
    29341 atttgcttta cagttttatt tttatttatt gcatttaagg ctactcaagg tgtagtagct
    29401 ttggtaaaaa gtatggataa aagtaataaa actaatcaac aacaaaatgt taactcagaa
    29461 caatttgacc ttggtaatga agaggaaaat aaaaagaaaa aatatactgt atttatagac
    29521 ccaggtcatg gaggcaatga taaaggaact gaaagcaaga ccagtaatag atatgaaaaa
    29581 gacctaaatc tacaaattgc aaaaaaatta gcaaataaat tatctaaaca aaaggatatt
    29641 caagtagtag tatccagaac tgatgataca tatatatcat taaaggatag agctatctta
    29701 gcaaataata gttctgctga tgtgcttgtt tctattcatt taaatgcaga gaaaaatggt
    29761 aatacagcaa caggtataga aacttggtat aggaataaag ctacagatgg ttcaaaagaa
    29821 cttgcacaga cagtacaaag tactatagta tcctatgtta aagttagaga taggggaata
    29881 gttgaaaata actttgaagt acttagagaa tcaaatatgc ctgctatatt aatagagtgt
    29941 ggttttttaa caacaccttc agaggaacaa aaaataataa atgaaaaata tcaagaccaa
    30001 cttgcggaag gaattgttca aggtgtactt tcatacctag attctaaagg gaataagtaa
    30061 gttaacttta ctttaatgtg aggataaatt taaaagttta actgtgtaaa ttgtattaac
    30121 tttatttcgt aatgttgcaa acattgtttg aatttagaaa ctatgaaatt agaaattatt
    30181 ttatctatat ctaatttcat agtttttttt gcaaaaaatt tat
//
LOCUS       DAYAOO010000045        30123 bp    DNA     linear   BCT 12-OCT-2024
DEFINITION  TPA_asm: Clostridioides difficile isolate ST8-SSI-h139-18
            SAMN40601845-rid21577343.denovo.045, whole genome shotgun sequence.
ACCESSION   DAYAOO010000045 DAYAOO010000000
VERSION     DAYAOO010000045.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN40601845
            Sequence Read Archive: SRR28438827
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 30123)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 30123)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-MAY-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-MAY-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002157583.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002157583.1
            Genome Coverage       :: 163x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/11/2024 16:19:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 4,038
            CDSs (total)                      :: 3,963
            Genes (coding)                    :: 3,930
            CDSs (with protein)               :: 3,930
            Genes (RNA)                       :: 75
            rRNAs                             :: 6, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 60
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 33
            CDSs (without protein)            :: 33
            Pseudo Genes (ambiguous residues) :: 0 of 33
            Pseudo Genes (frameshifted)       :: 7 of 33
            Pseudo Genes (incomplete)         :: 25 of 33
            Pseudo Genes (internal stop)      :: 11 of 33
            Pseudo Genes (multiple problems)  :: 8 of 33
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..30123
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN40601845-rid21577343.denovo.045"
                     /isolate="ST8-SSI-h139-18"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Denmark"
                     /collection_date="2018"
                     /collected_by="Statens Serum Institute"
     gene            complement(<1..932)
                     /gene="bclA2"
                     /locus_tag="ACGI5H_002248"
     CDS             complement(<1..932)
                     /gene="bclA2"
                     /locus_tag="ACGI5H_002248"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861885.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="collagen-like exosporium glycoprotein BclA2"
                     /protein_id="HFG9697951.1"
                     /translation="MSDISGPSLYQDVGPTGPTGATGPTGPTGPRGATGATGANGITG
                     PTGNTGATGANGITGPTGNMGATGANGTTGSTGPTGNTGATGANGITGPTGNTGATGA
                     NGITGPTGNKGATGANGITGSTGPTGNTGATGANGITGPTGNTGATGATGPTGLTGAT
                     GATGANGITGPTGNTGATGANGVTGATGPTGNTGATGPTGSIGATGATGTTGATGPIG
                     ATGATGADGEVGPTGAVGATGPDGLVGPTGPTGPTGATGANGLVGPTGPTGATGANGL
                     VGPTGATGATGVAGAIGPTGAVGATGPTGADGAVG"
     gene            complement(1310..1849)
                     /gene="hpt"
                     /locus_tag="ACGI5H_002249"
     CDS             complement(1310..1849)
                     /gene="hpt"
                     /locus_tag="ACGI5H_002249"
                     /EC_number="2.4.2.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422077.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0006166 - purine ribonucleoside salvage
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="hypoxanthine phosphoribosyltransferase"
                     /protein_id="HFG9697952.1"
                     /translation="MDIETKKWEVLYSEEKIKDKLRELGAIIEKDYKDKNLMVVSLLK
                     GSFIFCADLVRNINLPLRVNFMTTSSYGNNEESTGRVKVVSDVTTDIAGYDVLVVDDI
                     TDSALTMDFVLKHLKAKNPASLKCCVLLDKPSRRKVDLVPDYCGFEIEDKFVVGYGFD
                     FGDYYRNVPYIFNVTDEDR"
     gene            complement(2177..3484)
                     /locus_tag="ACGI5H_002250"
     CDS             complement(2177..3484)
                     /locus_tag="ACGI5H_002250"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454042.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine dehydratase subunit alpha family protein"
                     /protein_id="HFG9697953.1"
                     /translation="MRDIRKELVEMLKAEVKPAVGCTEPVALALACAKAKELLGEEIV
                     ENRMLVSPSIYKNGMCVGIPGTERLGLKIAAALGIVGGHSENGLSVLETLTKEEVKIA
                     EDYMDNTPLSITPADTREKVFIEVVLKGKNHIAKVRIRTKHDNFTFLEKDGEVLLDNE
                     PKVSASNDAAEKAESLMDTVTIQELIKNVEEIDFKDIEFLLDGVKMNEEMAEYGLKQK
                     TGIGVGYGIKKSIEEGLLGNDVINYAMMLTAGASDARMAGVKMPVMSSNGSGNHGLTA
                     ILPIVAYNKKFPQSDERLAKALAISHLVTGYIKNYTGRLSAVCGCGVAASTGATAGIS
                     WLMNGTEKQIEGAIENMIADLSGMICDGAKAGCALKLSSAASAAIQSAIIAKQDCFVP
                     PLNGIVGSSVEQSIQNLGRVSDKGMSITDEIILNVMNDMNKVD"
     gene            complement(3909..5684)
                     /locus_tag="ACGI5H_002251"
     CDS             complement(3909..5684)
                     /locus_tag="ACGI5H_002251"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428083.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0008134 - transcription factor binding
                     [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sigma 54-interacting transcriptional regulator"
                     /protein_id="HFG9697954.1"
                     /translation="MMIMIGLEYIKSDIQNIAEAIVSVLNIDVTIVNKELFRIAGTGV
                     YIDKIGEKVDKYTAFKKSLTEQITILIDDPKSSDICRECYKSGACVEFAEVCCPIICD
                     GDSHGVIGLIAFTKEQAQIIENNKSGLINFLGKMADLISNKLKAQIKTYELELEKKKL
                     ETLLNNMDKAVVSIDVDGKIDKYNSKFKELFNIKDSITGKNIFVELDFIKKPSINNFK
                     KDKSCSFFYKRYGYDSKGIYNINKIVLKNELKGYVIDFIDKRDAIKNYNKMNKDYRIK
                     LENIIGESVAIRNSKKEALIASKSTSTVLITGESGTGKELFARAIHNHSNRVDNPFIA
                     VNCAAIPDNLLESELFGYEEGAFTGAKKGGKLGMFEVAHKGSIFLDEIGDMSLHLQSK
                     LLRVLQEKELNKIGSKSNVSIDVRIIAATNKDLERMVQNGTFREDLYYRLNVIPIKLP
                     SLRERKEDIPLIIKHMVKEYSKKLDKNVIDIDSRVVDAMMEYKWPGNIRELQNIIEYS
                     VNMSSSSIITMNVIPQKIKNTSVEELEVKSDRIIPLDELEKIEIIKALNKYKDYKKDK
                     ELTAKALGISRATLYRKIEKYNIIS"
     gene            complement(5681..5818)
                     /locus_tag="ACGI5H_002252"
     CDS             complement(5681..5818)
                     /locus_tag="ACGI5H_002252"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422082.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9697955.1"
                     /translation="MEINYELIIIVMLFVILMSIQFTLNKIYLILKEIRQILMLKKNK
                     E"
     gene            complement(5896..6465)
                     /locus_tag="ACGI5H_002253"
     CDS             complement(5896..6465)
                     /locus_tag="ACGI5H_002253"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422084.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008757 - S-adenosylmethionine-dependent
                     methyltransferase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="methyltransferase domain-containing protein"
                     /protein_id="HFG9697956.1"
                     /translation="MKSILCQINKQPVKAKYTSDELECFLDTIEYNVGDKILLVGHIG
                     NLGKRLRGLGTSVTILENSNYEDVCYSLVYNENCNVVKGKLEFLPFDDNQFNKIIIVD
                     QFNVITDCEKASSEIQRVLKGNGEVILEDLNLKNLKVKLNYLKHKFCGSVAKIHYPHE
                     VFNIFSRLNFDGMIKESNKLKYIYVGKRR"
     gene            complement(6649..7284)
                     /locus_tag="ACGI5H_002254"
     CDS             complement(6649..7284)
                     /locus_tag="ACGI5H_002254"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422086.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded DNA-binding protein"
                     /protein_id="HFG9697957.1"
                     /translation="MIAVKDENNVVNLRGELDNKLEFSHEIFGEKFYNMKIKINRLSD
                     SFDILPMTVSERLLQDIDLDKQNLVNVVGQLRSYNKTLNNKNRLVLTVFVREIKSIDE
                     ENKDPNSIFLDGYVCKEPVYRKTPLGREITDLLVAINRPYNKSDYIPSIVWGRNAKFA
                     KNLKVGDRIQLWGRVQSREYEKKIDENNVVKKMAYEVSISKIKKLDENNNE"
     gene            complement(7952..8833)
                     /locus_tag="ACGI5H_002255"
     CDS             complement(7952..8833)
                     /locus_tag="ACGI5H_002255"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422088.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TSUP family transporter"
                     /protein_id="HFG9697958.1"
                     /translation="MVAILKALYVVFAAIFAVVFGKDVAKANKEGKLEEQSTPKVAVT
                     GFITDFFDTLGIGSFAPTIAMSKALKLNIPDKKMPGTLNVAHTIPVVTEAFIFTSIIP
                     VDGVTLVSMVVAAAVGSYIGAGIIAKMDERKIQLVMGVTLALTAILMLLGHPWINVLP
                     GGGNELGLTGAKLVIGVIGNFILGALMTAGIGLYAPGMAMVYFLGMSAKVAFPIVMGS
                     CALLMPVASMKFIKEDAYTKKASVIIAICGLIGVFVAAYIVKTLPMDILKALVIVVIA
                     YTSATMIMAANKNKKTA"
     gene            complement(8953..9960)
                     /locus_tag="ACGI5H_002256"
     CDS             complement(8953..9960)
                     /locus_tag="ACGI5H_002256"
                     /EC_number="5.1.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422090.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="proline racemase"
                     /protein_id="HFG9697959.1"
                     /translation="MKFSRSIQAIDSHTAGEATRIVVGGIPNIKGNSMPEKKEYLEEN
                     LDYLRTAIMLEPRGHNDMFGSVMTQPCCPDADFGIIFMDGGGYLNMCGHGTIGAMTAA
                     IETGVVPAVEPVTHVVMEAPAGIIRGDVTVVDGKAKEVSFLNVPAFLYKEGVEVDLPG
                     VGTVKFDISFGGSFFAIIHASQLGLKIEPQNAGKLTELAMKLRDIINEKIEIQHPTLA
                     HIKTVDLVEIYDEPTHPEATYKNVVIFGQGQVDRSPCGTGTSAKLATLHAKGELKVGE
                     KFVYESILGTLFKGEIVEETKVADFNAVVPKITGSAYITGFNHFVIDEEDPLKHGFIL
                     K"
     gene            complement(9980..10453)
                     /locus_tag="ACGI5H_002257"
     CDS             complement(9980..10453)
                     /locus_tag="ACGI5H_002257"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009906357.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0050485 - oxidoreductase activity, acting
                     on X-H and Y-H to form an X-Y bond, with a disulfide as
                     acceptor [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycine/sarcosine/betaine reductase component B
                     subunit"
                     /protein_id="HFG9697960.1"
                     /translation="MGISTSMKNTSLHIFRDPLLDLIDNDSDIDLLGVVVVGTSEHNE
                     WKTFLATRLGRWIESLRPDGVIITLDMAGNQHIDFTNAIAEFVKSDIPTVGLTIMGAD
                     GLVITNPYLDKATIIDYKKTTGYIETEVVGDNHMDEVDVKKALAFLKLKMRKDAK"
     gene            complement(10480..10947)
                     /locus_tag="ACGI5H_002258"
     CDS             complement(10480..10947)
                     /locus_tag="ACGI5H_002258"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422094.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0050485 - oxidoreductase activity, acting
                     on X-H and Y-H to form an X-Y bond, with a disulfide as
                     acceptor [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycine/sarcosine/betaine reductase component B
                     subunit"
                     /protein_id="HFG9697961.1"
                     /translation="MGIGPSTKETSLHHFRDPLLDIVESDKDVDLLGVIVVGTPDGNE
                     NKTFVGQRTAAWLEAMRVDGAIVSSDGWGNSHVDYANTFEEIGKRDIPVVGVTFNGTQ
                     AKFVVSNQYMDTIVDMNKSKEGIETEVVGENNTNEIDAKKALAFLKLKMRKHG"
     gene            complement(10962..11720)
                     /gene="prdD"
                     /locus_tag="ACGI5H_002259"
     CDS             complement(10962..11720)
                     /gene="prdD"
                     /locus_tag="ACGI5H_002259"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903671.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="proline reductase cluster protein PrdD"
                     /protein_id="HFG9697962.1"
                     /translation="MEEKIMRRLVIKPFHMNEVNFGSKTSIKKDVLTIDLSSIDEIKE
                     REELITDIKVDIIKPGDYDREINTIMDIIPISTKVLGRLGEGITHTLTGVYVMLTGAD
                     EDGNQMHEFGSSEGILKDQMVFGRYGTPSVEDYIIHVDVTLKGGLPFERTLPLAAFRA
                     CDDFIQEIRASLKMEDGRNATQVREYFDKIRPNAKKVVIVKQIAGQGAMYDNQLFSKE
                     PSGFEGGTSIIDMGNVPMIISPNEYRDGALRAMT"
     gene            complement(11800..12525)
                     /gene="prdB"
                     /locus_tag="ACGI5H_002260"
     CDS             complement(11800..12525)
                     /gene="prdB"
                     /locus_tag="ACGI5H_002260"
                     /EC_number="1.21.4.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861888.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0050002 - D-proline reductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_except=(pos:complement(12073..12075),aa:Sec)
                     /transl_table=11
                     /product="D-proline reductase (dithiol) protein PrdB"
                     /protein_id="HFG9697963.1"
                     /translation="MSLTTVQGLQSEIFVPITPPPVWTPVTKELKDMTIALATAAGVH
                     LKSDKRFNLAGDTTFRAIPNTATVDEMMVSHGGYDNGDVNKDINCMFPIDRLHELAAE
                     GFIKGVAPMHYAFMGGGGNQHVFTEETGPAIAAKLKEEGVDGVVMTAGUGTCHRTAVI
                     VQRAIEEAGIPTIIIAALPPVVRQNGTPRAVAPLVPMGANAGEPHNIEMQTHILRDTL
                     EQLVAIPSAGKIVPLPYEYKAHV"
     gene            complement(12563..12847)
                     /locus_tag="ACGI5H_002261"
     CDS             complement(12563..12847)
                     /locus_tag="ACGI5H_002261"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422102.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CBO2463/CBO2479 domain-containing protein"
                     /protein_id="HFG9697964.1"
                     /translation="MDRLKYISSETFYEGIIVDIKGGGVTIDLKGRLGQFKIPNRMLI
                     TDYELKIGQEVGFMLSYPEVLSPEPNQEYVENIRREKEKQAEMQSKQEEK"
     gene            complement(12928..14808)
                     /gene="prdA"
                     /locus_tag="ACGI5H_002262"
     CDS             complement(12928..14808)
                     /gene="prdA"
                     /locus_tag="ACGI5H_002262"
                     /EC_number="1.21.4.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422104.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0050002 - D-proline reductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="D-proline reductase (dithiol) proprotein PrdA"
                     /protein_id="HFG9697965.1"
                     /translation="MSITLETAQAHANDPAVCCCRFEAGTIIAPENLEDPAIFADLED
                     SGLLTIPENGLTIGQVLGAKLKETLDALSPMTTDNVEGYKAGEAKEEVVEETVEEAAP
                     VSEAAVVPVSTGVAGETVKIHIGEGKNISLEIPLSVAGQAGVAAPVANVAAPVASAAA
                     EVAPKVEEKKLLRSLTKKHFKIDKVEFADETKIEGTTLYIRNAEEICKEANETQELVV
                     DMKLEIITPDKYETYSEAVLDIQPIATKEEGELGSGITRVIDGAVMVLTGTDEDGVQI
                     GEFGSSEGELNTTIMWGRPGAADKGEIFIKGQVTIKAGTNMERPGPLAAHRAFDYVTQ
                     EIREALKKVDNSLVVDEEVIEQYRREGKKKVVVIKEIMGQGAMHDNLILPVEPVGTLG
                     AQPNVDLGNMPVVLSPLEVLDGGIHALTCIGPASKEMSRHYWREPLVIRAMEDEEIDL
                     VGVVFVGSPQVNAEKFYVSKRLGMLVEAMEVDGAVVTTEGFGNNHIDFASHIEQIGMR
                     GIPVVGVSFSAVQGALVVGNKYMTHMVDNNKSKQGIENEILSNNTLAPEDAVRIMAML
                     KNAIEGVEVKAPERKWNPNVKLNNIEAIEKVTGEKIVLEENEQSLPMSKKRREIYEKD
                     EN"
     gene            complement(15237..16997)
                     /gene="prdR"
                     /locus_tag="ACGI5H_002263"
     CDS             complement(15237..16997)
                     /gene="prdR"
                     /locus_tag="ACGI5H_002263"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422107.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-54 dependent transcriptional regulator
                     PrdR"
                     /protein_id="HFG9697966.1"
                     /translation="MFSIPEVKKVEEVMDTKFTTIDEDTRIEDAIKEMIKSNTKTLMV
                     IDSSDQLKGIISMTDIHNLYEMHKKYEGQPVKLIMKKDVIYVNEGLTLDECRDIMILK
                     NIGILPVLRDNKIIGVLKQEHIRDYLYMHLEDYGLTLKYIIGQIKEGICAINNEGVVI
                     LWNKFMEERYDIKSEDIVGRPMNEFLENTISEKVLNSKVGMSDLYFTDKKENMYALVH
                     ANPIFYKEEFIGVVCTEVDVTEAKILALELEKVNDTLKYLKNEVKNLSKGSFDKILGK
                     SYKLEKSKAIAKQVARTNSSIFIWGESGTGKEVFARAIHDYSERKGQFIPVNCSAIPN
                     ELFESEFFGYESGAFTGASKKGRIGIFELAKDGTVFLDEIADLPLSMQAKLLRVLQEK
                     EIRRVGGDTTIKINPRIISATNKDLSKMVKAEKFREDLYYRLNVVEIKIPPLRERKED
                     IGLLVHSFLEEICKQNNKPVLTISKDVIDIFQNYRWKGNIRELKNTIENIVVLSQNSK
                     IDVDDVPSYMMDSTNNSTEEEEYPLDLTKATQKIEIKNITKALKMSNGNKAKAAKILN
                     IPRTTLYYKIDQYKIDVSKI"
     gene            complement(17404..19578)
                     /locus_tag="ACGI5H_002264"
     CDS             complement(17404..19578)
                     /locus_tag="ACGI5H_002264"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898383.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cys-Gln thioester bond-forming surface protein"
                     /protein_id="HFG9697967.1"
                     /translation="MKTKIKKSSIISLVIAFSMVFTAFTPIVSYADEVTSNDTILNGE
                     EQSNGQTPDVEKPSDGQVPDGEKPSDSQVPDGEKPSDGQVPDGEKPSDGQIPDGEKPS
                     DGQIPDGEKPSDGQIPDGEKPSDGQIPDGEKPSDGQMPDGEKTSDSQTPDVEKPSDGQ
                     MPDGEKPLDEQTPEEEKPLEEEIVIEEMSLKQDIDKILDMTLSQINKIVYNFWEDEED
                     VKADEQSEINQVFTSEDSFISLWYDKKAKVKNSCLLKEIDGSDRPYHDLRFDDITKTL
                     TFDYVIKGLVGASSKDDKYVIEGEDGEQTAFCYNNHLRPPSSNGKSPYLPAEDFNGQE
                     NQNEEAVKSILYAGSEFDGFGYKQQFNLGGEENELMTYSATQSAIWIILGQMDEQERL
                     KQYQGSINLCDKLIERAKTEEERAEYQKKKEVAINIKAYLEALLKAGREELKPNDTGK
                     PSLSNGLTKINFEKNEDGTYETEAVALVGYSGVVKLRLPDGVTAYDGDGNIIGTGEVE
                     ISTQQKFKLKSVVKPDAKANISAVSYDYIFPKAIQYYKAVLDLGQKDHSSSLPSSKQN
                     LLSYTIEKKNGQEVNFNIGLPTDDVVNPPVPPTDDTNGHKPKPSPPIDDTVINPPVPP
                     MDDTIINPPVPPTEDAVLNPPVPPTEDAVLNPPVPPTEDTVLNPPVPSVSDTVEKTPE
                     LSRDDTIIKSPKTGDETQLMSYVFISVIAICGLAYQCKIKRN"
     gene            complement(19733..19861)
                     /locus_tag="ACGI5H_002265"
     CDS             complement(19733..19861)
                     /locus_tag="ACGI5H_002265"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9697968.1"
                     /translation="MDNQQVSFEKKKLQRLERNLVPTSVGKWGVPNLWLGNDIVCA"
     regulatory      complement(20160..20245)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF01786"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="cyclic di-GMP riboswitch class II; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /bound_moiety="cyclic di-GMP"
                     /db_xref="RFAM:RF01786"
     gene            complement(20650..21963)
                     /gene="prdC"
                     /locus_tag="ACGI5H_002266"
     CDS             complement(20650..21963)
                     /gene="prdC"
                     /locus_tag="ACGI5H_002266"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003431873.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="proline reductase-associated electron transfer
                     protein PrdC"
                     /protein_id="HFG9697969.1"
                     /translation="MNKLYSILLKQHVGGPDKPVVSVGDVVKKGTLIAEPTGLGANIY
                     ASVSGKISEINDQAIVIEADEVQEDTFEPLKGEGILDLIKEAGVVGMGGAGFPTHVKL
                     NIDLNGGTILANAAECEPLLAHNIKEIEERPEIVYQGIKYAMEVTNAGKGMLAIKSKH
                     PKAIEAFKKVIKPGDNIEVAELVDMYPMGEERAIVRDVLGKLLEPTQLPSEANAVVIN
                     VETLTRIVEAVEQKRPVISKNITVVGQLNSGKESIVFEDVPIGTTVGELIERAGGIKG
                     EYGEIILGGPFTGKATTLDAPITKTSGGIIVTMPFVNEKRKMGLLVCACGPNEERMRD
                     IATKMGVTDIVSVQKCKQAQEIKGALKCENPGHCPGQAQKCIEFKKAGAEVILIGNCT
                     DCSNTVMGSAPKLKLGVYHITDHVMRTVNHPLIRRIKGDVRLKIK"
     gene            complement(22352..23116)
                     /locus_tag="ACGI5H_002267"
     CDS             complement(22352..23116)
                     /locus_tag="ACGI5H_002267"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891705.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016810 - hydrolase activity, acting on
                     carbon-nitrogen (but not peptide) bonds [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide deacetylase family protein"
                     /protein_id="HFG9697970.1"
                     /translation="MKREVKRTKALIYSVLFFSLLLVLIFVFVYGIKYICSKSDNSKM
                     PIYKVDTNEKKIALSFDVAWGTDNMDDILKILDKHNVKATFFLVGSWVDDNEEIVKAI
                     DEKGHEIGNHSNTHANLKEISKEDITKEIETTSEKIYNITGKRTNLFRPPFGDVNNKA
                     MDICSDLGYKVIKWDVDSIDWKELGPNHVIEKVIKESQPGSIVLFHANINDVDNYLDT
                     IISRLKKDGYSLVKISDLLYKDNYVVDSNGVQKTKN"
     gene            23407..23610
                     /locus_tag="ACGI5H_002268"
     CDS             23407..23610
                     /locus_tag="ACGI5H_002268"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422115.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003690 - double-stranded DNA binding
                     [Evidence IEA];
                     GO_process: GO:0006265 - DNA topological change [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="small, acid-soluble spore protein, alpha/beta
                     type"
                     /protein_id="HFG9697971.1"
                     /translation="MSNSNRTVVPEAKAALNQMKLEIANEIGLSNYENIDKGNLTARE
                     NGYVGGYMTKKLVEMAERQMAGK"
     gene            23801..24337
                     /locus_tag="ACGI5H_002269"
     CDS             23801..24337
                     /locus_tag="ACGI5H_002269"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891708.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4364 family protein"
                     /protein_id="HFG9697972.1"
                     /translation="MFENSSEELAYHKLLILYILEKIKMDLTNSQITQVVLETEMMNY
                     FSLQQLLSQLMESKFLTTYKDSDREYYALTQRGVESLEYFFNRIPTSVTEKIDKYIDS
                     NKENLLADTQVKSSFVKQSDNEFIVNLRVIENQSNLIDLNLNVSSEKQAKLICNNWKN
                     NASYMYAEVIDLLIRDIH"
     gene            complement(24341..25207)
                     /locus_tag="ACGI5H_002270"
     CDS             complement(24341..25207)
                     /locus_tag="ACGI5H_002270"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422120.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YncE family protein"
                     /protein_id="HFG9697973.1"
                     /translation="MKIYISNYLSKSISIVDYSTLELEKEIVLEDNIYPHHFCIEKEK
                     NLIYIPSSSNGILYVLDLSNDKIIDTVSIGGSLSQVVLSDNELFVANEDSNSIYVLDK
                     NTLNPIGIIGVDNMPHGFDFDRESKKLYVPCINSIVCIDTINKNIQKKINMDFRAWHI
                     ELDKQKKEMYISTLDGKLIIIDEVSMDIKKVLYEFLLPVEIRFNYSGKKVYVADLGYN
                     NVRILDYTTSRYIGNIEINGIPQGLEISKDEKLLFVSDTQENSVKVYETANNKLIKEI
                     KVGKEPTTIICL"
     gene            25355..25600
                     /locus_tag="ACGI5H_002271"
     CDS             25355..25600
                     /locus_tag="ACGI5H_002271"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891710.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003674 - molecular_function [Evidence
                     IEA];
                     GO_process: GO:0008150 - biological_process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR03905 family TSCPD domain-containing
                     protein"
                     /protein_id="HFG9697974.1"
                     /translation="MKVTFNPSGVCCREMIFEVDENNVIVDAEFIGGCNGNLSGLRSL
                     IIGQNALEVADKLNGIDCGGKGTSCPDQLSKAIRQSI"
     gene            complement(25714..27012)
                     /locus_tag="ACGI5H_002272"
     CDS             complement(25714..27012)
                     /locus_tag="ACGI5H_002272"
                     /EC_number="6.3.2.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903674.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004326 - tetrahydrofolylpolyglutamate
                     synthase activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0008841 - dihydrofolate synthase activity
                     [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0006730 - one-carbon metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="folylpolyglutamate synthase/dihydrofolate
                     synthase family protein"
                     /protein_id="HFG9697975.1"
                     /translation="MKYEEALEYISQTNKFGIRLGLENIGKLLELLGNPQETLNIIHV
                     AGTNGKGSVCSFVSNILRECGYKVGLYTSPYLETFTERIRVNGQNIPQDDVARIIELI
                     KEKIEIMVKEGYAYPTEFEVVTAMAFYYYSEQKVDFVALEVGLGGRYDATNIITKSLV
                     SVIVSISLDHTGILGDTIEKIAYEKAGIIKENGVVLVYDQTDEAKDVIKSVCKEKKAK
                     YIEVDFDDINIKKSDINSQIYDCTVMKETYRDLEIKLIGEHQINNSILAISVIKYLKD
                     INKLANINEESIRKGLINTKWPGRIEKIKENPIFIIDGAHNEDGAKSLAKALDKNFKG
                     RKLTLLIGMLEDKDIDSVLEILLSHFNKVITTTPNNPRAINSDILREKVLKYVDDVTS
                     KHEIEDAVNYTLETSSEDDIIISAGSLYMIGTVRTLVKKL"
     gene            complement(27145..28158)
                     /locus_tag="ACGI5H_002273"
     CDS             complement(27145..28158)
                     /locus_tag="ACGI5H_002273"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009900042.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008236 - serine-type peptidase activity
                     [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="S8 family serine peptidase"
                     /protein_id="HFG9697976.1"
                     /translation="MNNKVKVAVLDTGIDKEHDYLKDNLVGGIAFECMHDYIFISDKF
                     DDEDGHGTACASIIKKEYEDVELFVIKILRKDGITNIKVLEEALRYLLDTNIRLINLS
                     LSVIGVESVKGLFEVCYELFRKGKIIVCSLANDFDLSYPAMFNNVIGVRGFTLDGDDS
                     FWYNKKYDVQCVMDSNSYISCDINNSYRLPPKCNSYLSAKLTGKIAKILSEKPGITIS
                     DLNDKLESLATRNHWDSCDFDECSRIVNFKLDLYDKENALFMKVADVVRDCLDIEENN
                     EKLFKGSLFNKEIGLVYDNCFNLLKKLEHRFDIKFNYMDISKYDLVSIYTLTELVERY
                     KNL"
     gene            complement(29222..29932)
                     /gene="rgaR"
                     /locus_tag="ACGI5H_002274"
     CDS             complement(29222..29932)
                     /gene="rgaR"
                     /locus_tag="ACGI5H_002274"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003432343.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system response regulator RgaR"
                     /protein_id="HFG9697977.1"
                     /translation="MFRVVICDDEKIQRSILKEFTEKLLSERCLNYQILEFSCGEDLI
                     SKYPEKIDIIFLDIQMKDINGIEVAKKIRKFDEKVEIIFTTAFSEYAPQGYEVRAYRY
                     LVKPIEYSNFAMGVNLCIDNLQRKKERYIVLNSKKGFNRILIDSILYVETVKRDLVVH
                     TIGRDYKANMSMKQAEKLLCENGFFRCHTSFIVNLRRIEDLRDNMITINEQFIPISKY
                     RLKDLKVALTSLLCDIMY"
BASE COUNT         9128 a         5565 c         3362 g        12068 t
ORIGIN      
        1 cctactgctc catctgctcc cgttgggcct gttgctccta ctgctcctgt tggacctatt
       61 gccccagcta ctcctgttgc tcctgtcgct cctgttggac ctaccaaacc atttgctcca
      121 gttgctccgg ttgggcctgt tgggcctacc aaaccatttg ctccagttgc tccggttggg
      181 cctgttgggc ctgttggacc taccaaacca tctggacctg ttgctcctac tgctcctgtt
      241 ggacctacct ctccatctgc tcctgttgct ccggttgctc ctattgggcc tgttgcccca
      301 gttgttcctg ttgctcctgt cgctcctata cttccggttg gacctgttgc tcctgtattt
      361 cctgttgggc ctgtagcacc tgttactcca tttgctccgg ttgctcctgt atttcctgtt
      421 ggacctgtta ttccatttgc tccggttgct ccggttgctc cagttagtcc ggttggacct
      481 gttgctccag ttgctcctgt attccctgtt ggacctgtta ttccatttgc tccagtcgct
      541 cctgtatttc ctgttggtcc tgtagagcct gttattccat ttgctccagt tgctcctttg
      601 tttcctgttg gacctgttat tccatttgct ccggttgctc ctgtattccc tgtcggacct
      661 gttattccat tcgctccagt cgctcctgta tttcctgttg gtcctgtaga gcctgttgtt
      721 ccatttgctc cagtcgctcc catatttcct gttggtcccg ttattccatt cgccccggtt
      781 gctcccgtat ttcctgttgg acctgttatt ccatttgctc cggtcgctcc agttgcacct
      841 ctaggccccg tcggtcctgt tggaccagta gcacctgttg gccctgttgg acctacatct
      901 tgatataaac ttggacctga aatatcactc atataattaa tcctcctttt ttaaagttag
      961 agtattactc tataaatatt gagtattact ctatataatt atatgaatcg acaatttctt
     1021 atgtgataat gtatctattt gcttatatca acatatatgc tttgattctt gaatttcatt
     1081 acttttttgt aaaatctttt acaattatta gtactctttt acaattatta atacaattaa
     1141 aaaactcatt ttccatcaat tatttaaaat ttttttatta tgttataaaa aatagataat
     1201 taaattgcat aaaattaatt taatactact ttaattactt tgtaaataaa aaaacctcaa
     1261 cacgattaat aaaaatcata ttaaggcatc cacaaaatta tataattgct tatctatctt
     1321 catcagtaac attgaatata taaggaacat ttctataata atcaccaaaa tcaaacccat
     1381 atccaaccac aaacttatct tctatttcaa atccacaata atctggcact aaatcgactt
     1441 ttcttctgct tggtttatcc aaaagaacac aacattttaa actagcagga tttttagctt
     1501 ttaaatgttt taacacaaaa tccatagtaa gtgcagaatc agtaatatcg tctacaacca
     1561 aaacatcata tcctgctata tcagtagtca catctgaaac tactttaacc cttccagtac
     1621 tttcttcatt gtttccataa ctagatgtag tcataaaatt aactctaagt ggtaaattta
     1681 tatttctaac taagtctgca caaaatataa agctaccttt taatagagaa actaccataa
     1741 gatttttatc tttataatct ttttctataa ttgctcctaa ttcccttaat ttatctttaa
     1801 ttttttcttc tgaatacaat acttcccatt tttttgtttc tatatccata aaaagacctc
     1861 caattgtaat aatccttctt aattttataa gagattgctc actttttcaa tactcttatt
     1921 caatattagt caatattatt gagtttttat gttcattcaa caattattaa caatgtatct
     1981 tatattttaa gtagttcata tatccacact aaattacata ctatatattt tagacaaaaa
     2041 aagaaaaaac ttgcactaac aagttttttc tattatacat aaatttatac ataatcatat
     2101 tttattagag ggtactaatt aaatttattt atgctatttt tgttatacct cataatacaa
     2161 aacatattat aaagtactag tcaactttat tcatatcatt cattacattt aagattatct
     2221 catctgttat agacatacct ttgtcactta ctctacctaa gttttgtata ctttgctcaa
     2281 cacttgaacc aactatacca tttagtggtg gtacaaaaca atcttgctta gctattatag
     2341 cactttgtat agctgcagat gctgcagaag ataattttaa tgcacaacca gctttcgcac
     2401 cgtcacatat cattccactt aagtcagcta tcatattttc tatagctcct tctatttgct
     2461 tttcagtacc attcataagc caagagatac cagcagttgc tccagtagaa gcagcaacac
     2521 cacatccaca tacagcagat aatcttcctg tatagttctt aatataacca gttactagat
     2581 gagatatagc taaagctttt gctagtcttt catcagattg tgggaatttt ttattataag
     2641 caacgattgg aagaattgct gttaatccat gatttccact tccatttgaa ctcataacag
     2701 gcatttttac ccctgccatt cttgcatctg aagctccagc agttaacatc attgcataat
     2761 ttataacatc attacctaaa agaccttctt ctatagactt tttaattcca tacccgacac
     2821 caataccagt tttttgtttt aatccatatt cagccatctc ttcattcatt tttactccat
     2881 ctagtaaaaa ttctatatct ttaaaatcaa tttcttctac attttttatt aattcttgta
     2941 tagttactgt atccattaaa ctttcagctt tttctgccgc atcatttgaa gctgatactt
     3001 ttggttcatt gtctaataat acttctccat ctttttctaa gaacgtaaaa ttatcatgtt
     3061 tagttcttat tctcacttta gcaatatgat tttttccttt taacacaact tctataaata
     3121 ctttctctct tgtatcagca ggtgttattg atagtggagt attatccata taatcctcag
     3181 ctattttaac ttcctctttt gttagagttt ctaacacact taatccattt tcagaatgtc
     3241 cacctactat acctagagct gctgcaattt ttaatcctaa tctttcagta cctggtatac
     3301 ctacacacat accattttta tagatactag gactaactaa catacgattt tcaactattt
     3361 cttctcctaa taattccttt gcctttgcac atgctagagc taaggctact ggttcagtac
     3421 accctactgc tggtttaact tctgccttta acatttccac taattctttt cttatatctc
     3481 tcattatata taaacctccc aattaagttt agatttagta ctcaaataat tagttaaata
     3541 atttcttatc tatatttata gcaaaataca tgccatattt tttatatctt tttatatttt
     3601 tagtcttata ttctataacc attggtatga ctgcctctat ttatgtattt tttttatttg
     3661 tatagagtat ttatattctt taaaatggag aaacatatga caatttcgca aaaagacaaa
     3721 aaaaagtctc aaaatgagat tctatatcat tttgagacgg ctcaaatata ttatttttta
     3781 acttataaaa accatttttt aattcataaa aaaagattct gcaaaacact tatagtataa
     3841 gtttaaagct ttctttaaag ttatgaattt agaaaaattt aaattttata tagcttttta
     3901 ttatattact atgaaattat attgtatttt tcaatttttc tatataatgt agctcttgat
     3961 attccaagtg ctttagctgt taattcttta tcttttttat aatctttata cttatttaaa
     4021 gcttttatta tctcaatctt ctctagttca tcaagtggaa ttatcctatc gcttttaact
     4081 tctaactctt ctacagaggt attcttaatt ttttgaggaa ttacattcat tgtgattatt
     4141 gaagaagaag acatattcac actatattca ataatattct gcaactctct tatattccct
     4201 ggccacttat attccatcat agcatcaaca accctgctat ctatgtcaat aacattttta
     4261 tctaattttt ttgaatactc tttaaccata tgcttgatta taagtgggat atcttctttt
     4321 ctctctctta aacttggtaa ttttataggt ataacattta atctataata taaatcttct
     4381 ctaaaagtgc cattttgaac cattctttct aaatctttat ttgtagcagc aataattctt
     4441 acatctattg aaacatttga tttacttcca attttattaa gttccttttc ttgtaatact
     4501 ctcaataact ttgactgtaa atgcaaactc atatctccta tttcatctaa aaatatactt
     4561 cccttatgag ctacttcaaa cattccaagc tttccacctt ttttagctcc agtaaaagct
     4621 ccctcttcat atccaaataa ttcactctct aataaattat ccggtatagc agcacagttt
     4681 acagctataa aaggattatc tactctattg ctatggttgt gtatggctct tgcaaatagc
     4741 tccttacccg ttccactttc cccagtaata agtactgttg atgttgattt agaagctatt
     4801 agggcttcct ttttagaatt tcttatagct acactttctc caattatgtt ttccaatttt
     4861 attctataat ctttattcat cttattgtag ttttttatag catctctttt atctataaaa
     4921 tcaataacat atccctttaa ctcatttttt aatactattt tattgatgtt gtatattccc
     4981 ttcgaatcat atccgtatct tttataaaaa aaactacagg atttgtcctt cttaaagtta
     5041 tttatagaag gtttctttat aaaatctaac tcgacaaata tgtttttgcc agttatacta
     5101 tcttttatat tgaaaagctc tttaaatttt gaattatatt tatcaatttt tccatccaca
     5161 tcaatagaca caacagcttt gtccatattg tttaatagtg tctctaattt tttcttttct
     5221 aattcaagct cataagtttt aatttgtgct tttaatttat tagatattag gtctgccatt
     5281 ttgcctaaaa agtttataag accactttta ttattttcta taatttgtgc ttgttctttt
     5341 gtaaaggcta taaggcctat aacaccatga gaatcgccat cacatataat aggacaacac
     5401 acctctgcaa actctacaca agccccactt ttatagcatt ccctacatat atcactactc
     5461 tttgggtcat caattagtat tgtaatctgt tctgtaagtg attttttaaa agccgtatat
     5521 ttatctactt tctcacctat tttgtctata tatactcctg tacctgcaat cctaaataac
     5581 tccttattta ctatagttac atctatattg agtactgata ctatagcttc agctatattt
     5641 tgaatatcag attttatata ttctaaacct atcataatca tcattcctta tttttcttta
     5701 gcataagtat ttgtcttatt tctttaagaa tcaagtatat cttatttaaa gtaaattgga
     5761 ttgacatcag gattacaaag agcataacaa ttattattaa ctcataattt atttccatct
     5821 aaacatctcc ttataacaaa agactaggct taacctagtc ttttatatta tatccatatt
     5881 tatattttaa ctcatttatc ttctttttcc cacataaata tattttaatt tatttgactc
     5941 tttaatcata ccatcaaagt ttaatcttga aaatatatta aatacttcat gtggatagtg
     6001 aatctttgca acagaaccac aaaatttatg tttaagatag tttaacttaa cttttaaatt
     6061 ttttaaattt aaatcctcta atataacctc tccattgccc tttaacactc tttgtatttc
     6121 agatgaagct ttttcacaat ctgtaataac attaaattgg tcaactatta ttatcttgtt
     6181 gaactgatta tcatcaaatg gtagaaactc taacttacct ttaactacat tgcaattttc
     6241 attatacact agagaataac agacatcttc ataattacta ttctccagta tagttacaga
     6301 agttccaaga cctctcaatc tcttgcctag gtttcctata tgaccaacaa gcaatatttt
     6361 atcacctaca ttatactcaa ttgtatccaa aaaacattct aattcatcag atgtatattt
     6421 agctttaact ggctgtttat ttatctgaca taatatgctt ttcacaatgc ttcacctctt
     6481 catttcctca attataaatt atgtacagat tacattataa taaatggcga gcaactattc
     6541 aagagatatt tcattagtat ttttttaaac aatctttata cattttaata tgatattata
     6601 ccaaatttat taggatttta ttcataaaaa tcagtctatt ttttatgttt attcattgtt
     6661 attttcatcc aattttttta ttttcgatat ggatacttca tatgccattt ttttgaccac
     6721 attattttca tctatttttt tctcatattc tctactttga accctacccc aaagctgtat
     6781 tctatcacca acctttagat tctttgcaaa tttagcattt ctaccccaaa ctattgatgg
     6841 tatataatca gatttattat aaggtctgtt tatagcaact aataaatcgg ttatttccct
     6901 tcctaaaggt gtcttcctat acacaggttc cttacataca tatccatcta aaaatatact
     6961 attagggtct ttattttcct cgtctatact ttttatttct ctgacaaaca ctgtaagcac
     7021 taatctattt ttattattta atgttttgtt atatgatctt aattggccta cgacattgac
     7081 taaattttgt ttatcaaggt caatatcttg gagaagtctt tctgatacag tcattggaag
     7141 tatatcaaaa gaatcgctta gtctgtttat ttttattttc atattataaa atttttctcc
     7201 aaatatctca tggctaaatt ctagcttatt gtctaactcc cctcttaagt ttactacgtt
     7261 attctcatct ttaacagcta tcatatttta tccctccaca attgttaatt cttatatttc
     7321 tggtatcagc ttatataata aatatattta taagggatgt attttattac aaatctttga
     7381 ttgctgttta aaagttttta tttagttata aatttcattt aatatttcac ttttataatt
     7441 ataaaattat tatctttttg taccacatat actaattaaa ctacctattt cagttttgta
     7501 ttaattataa aaatcctatt atataattaa taagtcatat ataacttaaa tttattcact
     7561 ctatataagc aacttcaacg aattaaattt attgaaataa ttcagatgaa tattgagtca
     7621 ttataaactt atttttctta attataagtt atattagact tattacaggt tatattttta
     7681 ttaatctgta ttaatatatg aacatttatt gaacttattg attataaaat ttaaatattt
     7741 agctttaaat tatgctttat tctttaaaaa tacaacgttt tttagattaa atctactaaa
     7801 tcactatata tattacataa ttggcatgtt aattgcttta tattaattta gtaaataaaa
     7861 aactgcccta aaatattaat tcaatatttt aaagcagttt ataatcttta ttattagctg
     7921 taatatttaa taaacactaa gtagtcttta actaagcagt ctttttgttt ttatttgcag
     7981 ccattatcat tgtagcagaa gtataagcta taactactat tactaatgct tttaatatat
     8041 ccattggtag agtttttact atatatgcag ctacgaaaac tcctattaaa ccacatatag
     8101 ctattataac tgatgctttt ttagtatatg catcttcttt tatgaatttc atacttgcaa
     8161 ctggcattaa taatgcacaa gaacccataa ctattgggaa tgcaactttt gcagacattc
     8221 ctaagaaata aaccattgcc atacctggag catatagacc tataccagct gtcattaaag
     8281 ctcctagtat aaagttacct attacaccta ttactaattt agcaccagta agacctaatt
     8341 catttcctcc acctggtaat acgttaatcc aaggatgacc taataacatt aatattgctg
     8401 ttaatgctaa agttacaccc ataacaagtt gtatttttct ctcgtccatc ttagctatta
     8461 ttcctgcacc tatatatgaa ccaactgctg ctgccacaac catagatact aaagtaacac
     8521 catctactgg gataattgat gtaaatatga atgcttctgt aacaactgga atagtatgtg
     8581 ctacgtttaa tgtaccaggc atttttttat ctggtatatt taactttaaa gcctttgaca
     8641 ttgctattgt tggagcaaat gaccctattc ctaatgtatc aaagaagtct gttataaatc
     8701 ctgttacagc aacttttgga gtactttgtt cttctagttt cccctctttg tttgctttag
     8761 ctacgtcttt accaaacaca actgcaaaga ttgctgcgaa tactacatat aatgccttta
     8821 agattgctac cataatccat cctcctattt ttttattttt tcatatattc tgaatcttat
     8881 agcctaaaag ctatagaata gcaaccgaca agtggctact attctatttt aatttcctaa
     8941 tttatttatt acttatttaa gaataaatcc atgtttaagt gggtcttctt catctattac
     9001 aaaatgatta aatccagtta tataagcaga accagttatt ttaggtacta cagcattgaa
     9061 atctgcaact ttagtttctt caactatttc acctttgaat aaagttccta atatactttc
     9121 atatacgaat ttttctccta cttttaattc acctttagca tgtaaagtag ctaatttagc
     9181 acttgttcca gttccacatg gagatctgtc aacttgacct tgaccaaata taactacatt
     9241 tttgtaagta gcttctggat gagttggctc atcatatatt tcaactaagt ctacagtttt
     9301 tatatgagct aaagttggat gttgtatttc tattttctca tttattatat ctctaagttt
     9361 catagctagt tcagttaatt taccagcatt ttgaggttcg atttttaaac ctaattgact
     9421 tgcatgtatt atagcaaaga agcttccacc aaatgatatg tcaaatttaa cagttccaac
     9481 acctggtaag tcaacttcaa caccttcttt atataagaaa gctggtacgt ttaagaatga
     9541 tacttcttta gcttttccat ctacaactgt aacgtctcct cttattattc ctgctggagc
     9601 ttccataact acatgagtta caggctctac tgctggaact acacctgttt ctatagctgc
     9661 tgtcatagct cctattgtac catggccaca catgttaagg tatccgccac catccatgaa
     9721 gattattcca aagtcagcat ctgggcaaca aggttgagtc attacagaac caaacatatc
     9781 attatgtcct cttggctcta acattatagc agttcttaaa taatctagat tttcctctaa
     9841 atattctttt ttctcaggca tagaatttcc ttttatgtta ggtattccac ctacaactat
     9901 tctagtcgct tcacctgctg tatgagagtc tatagcttgt atacttctgc taaatttcat
     9961 atcaaattcc cccttaggtt tattttgcgt ctttacgcat ttttaatttt aggaaagcca
    10021 atgctttttt aacatcaact tcatccatgt gattgtctcc aactacttct gtttctatgt
    10081 agcctgttgt ctttttataa tcaattatgg tagctttatc caaatatgga ttggtaatta
    10141 ctaatccatc tgctcccata atagtaagac ctactgtagg tatatctgat tttacaaact
    10201 ctgctatagc atttgtaaaa tcaatatgct ggtttcctgc catatctaaa gttataatca
    10261 ctccatcagg tcgcaatgat tcaatccatc ttccaagtct agttgctaaa aatgttttcc
    10321 attcattgtg ctctgatgtc ccaactacaa ccactcctaa caagtctatg tcagaatcat
    10381 tatctatcaa atctagtaac gggtctctaa atatatgaag tgatgtgttt ttcattgatg
    10441 tagaaattcc cacaaaactc attcccttac ttaaattttt tatccatgtt ttctcatttt
    10501 aagttttaaa aatgccaaag cttttttagc atctatttca tttgtgttgt tttctccaac
    10561 tacttctgtc tcaatacctt cttttgattt gttcatatca actatggtat ccatatattg
    10621 attgcttaca acaaacttag cttgagtccc attaaatgta actccaacta caggtatatc
    10681 tctttttcct atttcctcaa atgtgttagc gtagtcaaca tgtgagtttc cccaaccatc
    10741 tgatgaaact atagctccat ctactctcat ggcttccagc caagcggccg ttctttgtcc
    10801 cacaaaggtt ttattttcat ttccatctgg agttcctact actattactc caagtaaatc
    10861 tacatcctta tcactttcaa ctatgtctaa aagtgggtct ctaaagtgat gaagagatgt
    10921 ttcttttgtt gaaggtccta ttcccataat atccacctct cttaagtcat agctctaagg
    10981 gcaccatctc tgtattcatt aggagatata atcataggta catttcccat atctataatt
    11041 gatgttcctc cttcaaatcc actaggttcc tttgagaata actgattgtc atacatagca
    11101 ccttgacctg ctatttgttt tactatgaca accttttttg catttggtcg aattttgtca
    11161 aaatattcac gaacttgagt agcatttctt ccgtcttcca ttttcaaaga cgctcttatt
    11221 tcttgtataa aatcatcaca tgctctgaat gctgcaagtg gaagtgttct ttcaaaaggt
    11281 aaacctccct ttaaagttac atctacatgg attatataat cttcaactga tggagttcca
    11341 tatctcccaa ataccatttg gtctttcaaa attccttctg aagaaccaaa ttcatgcatt
    11401 tgatttccat cttcatctgc accagttaac attacatata cacccgttaa agtatgtgta
    11461 ataccctctc ccagtctgcc taaaactttt gttgatattg gtataatgtc cataatagta
    11521 ttaatttctc tgtcataatc tccaggtttt ataatgtcta cttttatgtc tgttattaac
    11581 tcttctcttt cttttatttc atctatactt gataaatcta ttgtaagtac atctttcttt
    11641 atagaagttt ttgaaccgaa attaacttca ttcatatgaa acggttttat aacaagtctt
    11701 ctcattattt tttcttccat aatatccacc tttgttctta aaacccctct cctaaccgtg
    11761 taggagaagg gttctatatt ttcaaatata aattacattt taaacgtgag ctttatattc
    11821 gtatggtaat ggaactatct taccagcaga tggtattgca actaattgct ctaatgtatc
    11881 tcttaatata tgtgtttgca tttctatatt atgtggttca ccagcattag cacccattgg
    11941 aactaatgga gcaactgctc taggagttcc gttttgtcta actactggag gaagagctgc
    12001 tattattatt gtaggtattc cagcttcctc tattgctctc tgcacgatca cggcagttct
    12061 atggcaagta cctcagccag ctgtcataac tacaccgtct actccctctt ccttaagttt
    12121 agcagcgata gcaggaccag tttcttcagt gaagacatgt tggtttcctc caccacccat
    12181 gaatgcatag tgcataggag ctactccttt gataaatcct tctgcagcta attcatgtaa
    12241 tctatctata gggaacatac agtttatatc tttgtttaca tctccattgt catatccacc
    12301 atgtgatacc atcatttcat caactgtagc tgtattaggt atagctctaa atgtagtatc
    12361 tcctgctaga ttaaatctct tgtcagattt taaatgaaca ccagctgctg tagctaaagc
    12421 tatagtcata tcttttaatt ctttagttac aggagtccaa actggaggag gtgttattgg
    12481 aacgaatatt tcagattgaa gtccttgtac tgttgtaagg ctcatatatt tcctctccct
    12541 tctattttca aacgattatt tattattttt cttcttgttt tgattgcatt tctgcttgtt
    12601 tttctttttc tctcctaata ttttctacat actcttgatt aggctctgga cttaatacct
    12661 caggatagct tagcatgaat ccaacttctt gacctatctt aagttcgtag tcagttataa
    12721 gcattctatt aggtatttta aattgtccaa gtctaccttt taggtctata gtcactccac
    12781 cgcctttgat gtcaactata ataccttcat aaaaagtctc tgatgagata tattttaacc
    12841 tatccattat aattctacct ctctatactg ttttaaactt ggatctaaat ttatgttatt
    12901 gtctaaatct tagttagtat ctaaatttta gttttcgtct ttttcgtata tttctcttct
    12961 cttcttactc attggtagag attgctcatt ctcttctaat actatttttt ctcctgtaac
    13021 tttttctata gcttctatgt tatttaattt aacatttgga ttccattttc tttcaggagc
    13081 tttaacttct acaccttcta tagcattttt aagcatagcc attattctaa cagcatcttc
    13141 tggagctaaa gtgttgttag ataatatttc attctctata ccttgcttag acttattgtt
    13201 gtctaccatg tgagtcatgt atttattacc aacaactaga gcaccttgaa cagctgagaa
    13261 acttacacca actactggta tacctctcat acctatttgc tctatgtgag atgcgaaatc
    13321 tatatggttg tttccgaaac cttcagtagt tactacagct ccatcaactt ccatagcttc
    13381 aactaacata cctaatctct tagatacata gaatttctca gcatttactt gtggagaacc
    13441 aacaaataca acacctacta aatctatttc ttcgtcttcc atagctctta ttactaatgg
    13501 ctctctccag taatgtcttg acatttcttt tgatgcaggt cctatacaag ttaatgcatg
    13561 gataccacca tctaatactt caagtggaga taatacaact ggcatgtttc ctaagtcaac
    13621 gtttggttga gctcctaatg taccaactgg ctcaactggt aatattaggt tatcatgcat
    13681 tgcaccttgt cccattattt cttttataac aacaactttc tttttacctt ctcttctgta
    13741 ttgctctatt acttcttcat caactactaa agagttgtca actttcttta atgcttctct
    13801 tatttcttga gttacatagt caaatgcacg gtgagcagct aaaggtcctg gtctttccat
    13861 gttagttcct gcttttattg ttacttgacc tttgatgaat atttcacctt tgtcagcagc
    13921 acctggtcta ccccacatta tagtagtatt taactcacct tctgaagaac caaattcacc
    13981 tatttgaact ccatcttcat ctgtaccagt taataccatt acagctccat ctataactct
    14041 agttatacct gaacctaatt cgccttcttc tttagtagcg attggttgta tatctaatac
    14101 agcttcactg taagtttcat atttatcagg agttattatt tctaacttca tatctacaac
    14161 taactcttga gtttcattag cttctttaca tatttcttct gcgtttctga tgtataaagt
    14221 agttccttct attttagttt catcagcaaa ttcaacttta tctattttaa agtgtttttt
    14281 agttaagctt cttaaaagtt tcttttcttc aacttttgga gctacttctg ctgctgcact
    14341 tgccactgga gcagcaacgt ttgctactgg agcagcaact cctgcttgac cagctactga
    14401 taaaggtatc tctaagctta tgttcttacc ttcacctatg tgtattttaa ctgtttcacc
    14461 tgcaactcct gtgcttactg gaactactgc tgcttctgat actggagctg cttcttctac
    14521 tgtttcttct actacttctt ctttagcctc tcctgctttg tatccttcta cgttatctgt
    14581 agtcattgga gaaagtgcat ctaaagtttc ttttaactta gctcctagta cttgacctat
    14641 agttaatcca ttttctggta ttgttaataa tccagaatcc tctaagtctg caaatattgc
    14701 tggatcttct aagttttctg gcgctataat tgttcccgct tcaaatctac aacaacaaac
    14761 tgctgggtca tttgcatggg cttgagctgt ttctaaagtt attgacatag tataaaatac
    14821 ctccttacat tattttctta tttattattt taaatctcaa ttcctcaaca ggtaacccct
    14881 taactgagaa attaagtaaa ttaaaaccta cataatttgt tatgattaat attatttttt
    14941 tctcacttaa agtcacttta tattataagc aattcctatg ccaacttatt aacaaaaaga
    15001 ttttttctat aatagattct tcatctatcg ctatttttag ccaaatatta tataaatatt
    15061 tatttaaaat atgttatttt ttgtatttgt aaacattttc tcaaacaaaa aaagtgtcaa
    15121 ttaatcaaca ctttttcatt ttttttaaca catctatata cacaacactt atataagcgt
    15181 tggctttact aggttttaaa ttaaagttta tcattttgtc aaaatttagt catgtgtcat
    15241 attttagaca catctatttt gtattggtct atcttataat acaaagttgt tctgggtata
    15301 tttaatatct tagctgcttt agctttattt ccattagaca ttttaagtgc cttggttata
    15361 ttctttattt caattttttg agttgccttc gttaaatcta aaggatactc ttcttcttca
    15421 gtactattat ttgtagaatc catcatataa cttggtacat catccacatc tattttagaa
    15481 ttttgtgaca atacaacaat attttcaatc gtatttttta attctctaat attacctttc
    15541 catctataat tctgaaatat atctattaca tctttgctaa ttgtaagaac aggcttatta
    15601 ttttgtttac atatctcctc taaaaagcta tgaaccaata atcctatgtc ttcttttctc
    15661 tctctaagtg gaggaatctt tatttcaaca acatttaatc tatagtataa atcttctcta
    15721 aatttttctg cctttaccat tttactcaaa tctttattgg tagctgatat tattctagga
    15781 tttattttta ttgtggtatc tccaccaact cttcttattt ctttttcctg taatactcta
    15841 agcaactttg cttgcatact aagaggtaaa tcggcaattt catctaaaaa tacagttcca
    15901 tcttttgcaa gttcaaatat acctattcga ccctttttac ttgctcctgt aaacgcacct
    15961 gattcatacc caaaaaactc actttcaaat aactcatttg gtatggcact acagttaaca
    16021 ggtataaatt gaccttttct ctcactataa tcatgaatag ctcttgcaaa tacttcttta
    16081 cctgtaccac tttcgcccca aataaatatg ctactatttg ttctagccac ttgttttgca
    16141 atcgctttcg atttttccaa tttataactt ttacctaaaa tcttatcaaa actaccttta
    16201 gataaatttt tgacttcgtt ctttagatat tttaatgtat catttacttt ttcaagttca
    16261 agagctaata tcttagcttc tgtaacatca acttctgtac atacaacacc gataaattct
    16321 tctttataaa atataggatt tgcatgaact aatgcataca tattttcttt tttatctgta
    16381 aaatacaagt cactcattcc aactttacta tttagtactt tttctgaaat agtattttcc
    16441 aaaaattcat tcatcggtcg accaactata tcttcagact ttatatcata cctttcctcc
    16501 ataaacttat tccacaagat aacaacacct tcgttattta tagcacaaat tccttcttta
    16561 atttgaccta taatatactt caaagttaat ccataatctt ctaaatgcat atatagatag
    16621 tccctaatgt gctcttgttt tagaactcca ataattttat tatctctaag aacaggaaga
    16681 atccctatat tttttaatat cattatatct ctacattcat ctaaggttaa accttcgttg
    16741 acatatatta catccttctt cattataagt tttactggtt gaccttcata ctttttatgc
    16801 atctcataaa gattatgtat atccgtcatg gatataatgc cttttaattg gtcagatgaa
    16861 tctattacca ttagagtttt tgtgttgctt tttatcattt cttttattgc atcttcaatt
    16921 cttgtgtctt cgtctatagt tgtaaatttt gtatccatta cctcttctac tttttttact
    16981 tctggtatcg aaaacataaa gtcccccctt tatagtagta cctcatcaaa acttatttat
    17041 atatatttat tctagcatat tataataatt atttattaaa taattattat taaaatttat
    17101 taagtaatta gcatttaaat ttatataatc actttaaaat ttataattaa atttatacaa
    17161 atgaaatcaa atgaattata cccttagtat attatttttt caatactatt ttcaccttca
    17221 aaacattttt ctattcatca aacaattaat gaatgcctgt atccaatcat aaatttaaga
    17281 atataattaa aatatatatt tttaaacaaa ctatatttgc atattatatt tacataaaaa
    17341 agccccaaaa tgacttataa atcaatttga gactttttat tttaaactta ataataatct
    17401 agattaattt ctttttattt tacattgata cgctaatcca caaattgcaa tgacactaat
    17461 aaatacatat gacattagct gagtttcatc acctgttttt ggtgatttta ttattgtatc
    17521 atctcttgat agttctggag ttttttccac tgtatcactt actgatggta ctggtggatt
    17581 taacactgta tcctctgttg gtggcactgg tggatttagc actgcatcct ccgttggtgg
    17641 cactggtgga tttaacactg catcctccgt tggtggtact ggtggattta ttattgtatc
    17701 atccattggt ggtactggtg gatttattac tgtatcatct attggtggtg atggttttgg
    17761 cttatgtcca tttgtatcat ctgttggtgg cactggtgga tttacaacat catctgttgg
    17821 tagacctata ttaaagttaa cttcttgacc attttttttc tctattgtat aacttaataa
    17881 attttgctta ctagatggta atgaagatga atggtctttt tgtcctaaat caagcactgc
    17941 cttataatat tgaatagctt ttggaaaaat ataatcataa gatacagcag aaatattagc
    18001 tttggcatct ggttttacaa cactcttaag tttaaatttc tgttgtgttg aaatttctac
    18061 ttcacctgta cctattatat taccatctcc atcataagca gttactccat ctggtagtct
    18121 taactttact acaccactat aacctactaa ggctacagct tctgtttcat aagtaccatc
    18181 ttcatttttt tcaaagttaa tcttagttaa accattactc aaactaggtt ttcctgtatc
    18241 atttggcttt aactcttcac gacctgcttt taacaatgct tctaaataag cttttatatt
    18301 tatagctact tctttcttct tctgatactc agctctttcc tcttcagttt ttgctctttc
    18361 tataagttta tcacaaaggt ttatagaacc ttgatactgc ttaagtcttt cttgttcatc
    18421 catttgtcca agaataatcc aaattgcact ttgagtagct gagtaagtca tcaattcatt
    18481 ttcttctcca cctaaattaa attgttgctt atatccaaat ccatcaaatt cagaacctgc
    18541 atatagtata gatttaactg cttcttcatt ttggttttct tgaccattaa aatcttctgc
    18601 tggtaaatat ggactctttc cattactact tggtggtctt aaatgattat tgtaacaaaa
    18661 tgcagtttgc tctccatctt caccttctat tacatatttg tcgtcttttg agcttgctcc
    18721 tacaagaccc tttattacat agtcaaaagt taaagtcttt gtaatatcat caaatcttaa
    18781 atcatgataa ggtctatctg aaccatctat ttcttttagt aaacaagaat tttttacttt
    18841 tgcttttttg tcataccata agctaataaa tgagtcttct gaagtaaaaa cttggttaat
    18901 ttctgattgt tcatctgcct ttacatcttc ttcatcttcc caaaagttat atactatttt
    18961 atttatttga gataaagtca tatcaagaat tttatcaata tcttgtttta aactcatttc
    19021 ctctataact atttcttctt ccaatggttt ttcttcttct ggagtttgct catctaatgg
    19081 tttctcccca tctggcatct gaccatctga tggtttctct acatctggcg tctgactatc
    19141 tgatgtcttc tctccatctg gcatctgacc atctgatggt ttctccccat ctggtatctg
    19201 accatctgat ggtttctctc catctggtat ctgaccatct gatggtttct ctccatctgg
    19261 tatctgacca tctgatggtt tctccccatc tggtatctga ccatctgatg gtttctcccc
    19321 atctggtacc tgaccgtctg atggtttctc cccatctggt acttgactgt ctgatggttt
    19381 ctccccatct ggtacctgac cgtctgatgg tttctctaca tctggtgtct gaccatttga
    19441 ttgttcttct ccattaagta ttgtatcatt gctagtcact tcgtcagcat aagatactat
    19501 tggtgtaaat gcagtaaaca ccatactaaa agcaattact aaactgatta tacttgattt
    19561 tttaattttt gttttcaaaa ttctcctgat actaaaaaca tatattgtat tcacttaata
    19621 taattaaaat tattaaatat tatatgaatc ttattcaata atacatcttt agtgtgttca
    19681 attagggtcg ttactcctaa ccagttctcc tatgaacttc ttaatatttc tattaagcac
    19741 agactatatc attacctaac cataaattag gtactcccca tttccccaca cttgtaggta
    19801 cgagatttct ctctagtcgt tgaagtttct tcttttcgaa gcttacctgc tgattatcca
    19861 ttttcaaggc acttaggatt taaccttatg ctatctaact aattttttct actttcgtaa
    19921 cctcaagtgc ttattaaatg cacactctat cacacttatc cttatttcat gattatgttg
    19981 tggtttagtt agctttagga acttccagca attaaaggag ttttgggcag atatctgcca
    20041 ctctacactc gttatgaatg cagggagcat ttcaaaaata tatttatatc tatcttctat
    20101 taattactta tttatgtatt tattttatat atttttgaca attaaaagtt actcctattt
    20161 atatttatag caggttgcac tactaactcc atatatcttt taagtgccca ggtttaagat
    20221 atacttcaca gtttctataa ataggttttt taatttttct tttttaactt tttaagtgca
    20281 cttttttaac aactcaataa aatataaatt agtatcctag atacttatct aataaaagac
    20341 aaaaattagt ttttataata aaaaagatac tatagagtat cttcaaatat cacaaaaacc
    20401 ttttactcta tcggatagtt gacttaatat aatatgcata ttaatacaaa ccacatactt
    20461 gagtatcatt atttttgtcc aatattaatt gtaatagcta ttattatcat tatacaatat
    20521 ctagcatatt ttgtctattt tttccattta ttttacaata tatatattgc cctcaaaata
    20581 cattaaaaaa catccttaga agtaactttt aagttttact tctaaagatg tctaacttct
    20641 atttatctat tattttattt ttaatcttac gtcacctttt attcttctta ttaatgggtg
    20701 attaactgtt ctcattacat ggtcagtaat atgatataca cctaatttta attttggtgc
    20761 agaacccatt actgtgttac tacagtcagt acagtttcct attaatataa cttctgctcc
    20821 agctttctta aattcaatac atttttgagc ttgtcctgga cagtgtcctg gattttcaca
    20881 ttttaatgca cctttaattt cttgagcttg tttacatttt tgaactgata ctatatcagt
    20941 aactcccatt ttagttgcta tatctctcat tctttcttca ttaggtccac atgcacaaac
    21001 taaaagaccc atttttctct tttcattaac aaatggcata gtaactatta taccaccact
    21061 agttttagtt attggagcat ctaaagtagt agctttacca gtgaaaggtc ctcctaggat
    21121 tatttcacca tattcacctt ttattccacc agctctttca attaattctc cgacagttgt
    21181 tccaattggc acatcttcaa acactataga ttcttttcca ctgtttaatt gaccaactac
    21241 agttatattt ttagatataa ctggtctttt ttgctcaaca gcctctacta ttctagttag
    21301 tgtttctacg tttattacta ctgcattagc ctctgaaggt aattgagttg gctcaagtaa
    21361 ttttcctaga acgtctctta ctattgctct ctcttctccc attgggtaca tatcaactag
    21421 ttctgcaact tctatgttgt ctcctggctt tattactttt ttgaaagctt ctattgcttt
    21481 tggatgctta ctttttattg ctagcatacc ttttccagca ttagtaactt ccatagcata
    21541 ttttatacct tgataaacta tttctggtct ttcttctatt tcttttatat tatgagctaa
    21601 taaaggttca cattcagctg catttgctaa tattgttcca ccatttaaat ctatgtttaa
    21661 ttttacatga gtagggaatc ctgctccacc cattcctact actccagctt ctttaattaa
    21721 gtcaagtata ccttctcctt ttaatggttc aaaagtatct tcttgtactt catcagcttc
    21781 aattactatc gcttggtcat ttatttcact tatttttcca ctaacactgg cataaatatt
    21841 tgcccctaat ccagttggtt ctgcgattag agttcctttt tttactacat ctccaacact
    21901 tactactggc ttatctggac caccaacgtg ttgttttaat aaaatagaat atagtttgtt
    21961 caactagtac gcccccttaa gtatattaat ttttttataa gctgttcaaa taatgttaat
    22021 gctatttttc tattataagg tcttaacata ttgtttattt ctatagaaca tatcgcttat
    22081 taacaaagca atttctatgc caacttttaa acaaacttat accctttgga aatactgtct
    22141 tacagcattc attaattctt ctaaattttt aaacccatca aaaaaaagtc aattattaga
    22201 cactttttta atcaatttaa tctataatta ttgatattgc atacatgtat aaaaagtgtc
    22261 aaaaaataga caccgtcttt ttatcgacac ttttctaaca tatactatat aatttatcac
    22321 aactttactt aaaatataca tttattactt attaattctt agttttttgc actccattgg
    22381 aatcaactac ataattatct ttatacaaca aatcagatat tttgactaga ctgtatccat
    22441 ctttttttag tcgacttatt atagtatcca aatagttatc tacatcattt atattagcat
    22501 ggaataaaac tattgaacca ggttgagatt cttttattac tttttcaatt acatgatttg
    22561 gtccaagctc cttccagtct atagaatcta catcccactt aattacttta taacctaaat
    22621 cactacaaat gtccatagct ttattgttta cgtccccaaa aggaggtcta aataaattag
    22681 tcctttttcc tgttatatta tatatttttt ctgatgtagt ttctatctct tttgttatgt
    22741 cttcttttga tatttccttc aaattggcat gagtatttga atgatttcca atttcatgtc
    22801 ctttttcatc tatagctttt acaatttctt cattatcatc cacccaacta ccaactaaaa
    22861 agaaggtagc ttttacatta tgtttatcta aaatttttaa aatatcatcc atattatcag
    22921 ttccccatgc tacatcaaaa ctcaaagcta tttttttctc atttgtatca actttatata
    22981 taggcatttt tgaattgtca gatttagaac atatgtattt tattccataa acaaaaacaa
    23041 atattaacac taataataat gaaaaaaata aaacactata tatcaaagct ttagtccttt
    23101 taacttctct tttcatacta ttcccccttt gaaataattt cttctatatt taaaatttat
    23161 tttttttcag ctcaaaaaag tactgtaata tttaatttat aagacaataa ctaaaaaaat
    23221 aaaacctata ttgacctaat taaactctct aaaatactca tttatttaat ttttttatat
    23281 tttttacatt tttaccttta tttttctgta tatattattt ttattttgga gaaattagta
    23341 ttaacatcac ataaataaaa gtgttgttag acatcataaa ctaattattt gaggaggaaa
    23401 tttactatgt caaattcaaa cagaacagta gttccagaag caaaagctgc tttaaaccaa
    23461 atgaaattag aaatagctaa cgaaataggt ttatctaact atgaaaacat agacaaaggt
    23521 aacttaacag ctagagaaaa tggatatgtt ggtggatata tgactaagaa attagttgaa
    23581 atggctgaaa gacaaatggc tggaaaataa atagtaaatt ttgacacctg ggtatcaaca
    23641 gggctgctaa ttagcagccc tgtttttcta tatttattta taaaattgtt tttatatgaa
    23701 ttattaaaga ttaataatac aatacaaatt gttcttttaa ttttgtacaa attagtttaa
    23761 tatattatat atagaaatag tttgacggag gatgatattt atgtttgaaa actcgtctga
    23821 agaattagcc tatcacaaac ttttaatttt atatatatta gaaaaaatta aaatggattt
    23881 aactaattct caaataactc aagtagtatt agagactgag atgatgaatt atttttcatt
    23941 acaacagctt ttatctcagc ttatggaatc taagtttttg actacatata aagactctga
    24001 cagagaatat tatgctctta ctcaaagagg cgtagaaagt ctagaatact tctttaatcg
    24061 aatacctact agtgttactg aaaaaataga caagtatata gattctaaca aagaaaatct
    24121 actagcagat actcaagtaa agtctagttt tgtaaaacaa agtgataatg aatttattgt
    24181 caaccttaga gtcatagaaa atcagtctaa cttaatagat ttaaatctaa atgtttcatc
    24241 agagaaacaa gcaaaactta tttgcaataa ctggaaaaat aatgcatctt atatgtatgc
    24301 cgaagttatc gatttactta taagagacat acattaaagc ctacaaacaa attatagttg
    24361 taggctcttt tcctaccttg atttctttta ttaatttgtt atttgcagtt tcataaactt
    24421 ttactgaatt ttcttgtgta tctgatacaa atagtaactt ttcatcttta gatatttcta
    24481 atccttgggg aatcccattt atttcaatat ttccaatgta tctactcgtt gtataatcta
    24541 aaattcttac attattataa cccaaatcag caacataaac ttttttgcca ctataattaa
    24601 atcttatttc tactggtaat aaaaattcat ataatacctt ttttatatcc atgcttactt
    24661 catctattat tataagcttt ccatcaagtg ttgatatata catttctttc ttttgtttat
    24721 caagttctat atgccaagct ctaaagtcca tatttatttt cttttgtata tttttattaa
    24781 ttgtatctat acatactatc gagtttatac acggtacata taactttttg ctttctctat
    24841 caaagtcaaa tccatgtggc atattatcaa ctccaataat tcctattgga tttaatgtgt
    24901 ttttatctag tacatatata ctattagaat cttcatttgc cacaaacaat tcattatcgc
    24961 taagtacaac ttgactaaga cttcctccta tagagacagt atcaattatt ttatcattac
    25021 ttaaatctaa gacatagagt atcccattac ttgaactagg tatgtatatt aaattttttt
    25081 ctttttctat gcaaaaatgg tgtggatata tattatcttc taatactatt tctttttcta
    25141 gttcaagtgt agaataatca actatgctaa tactctttga taagtagtta gaaatataga
    25201 ttttcatata acccctcctc tctacaatac atatactaca ataatatatt atttcattag
    25261 cttgtattat gctttatagt tgcattatta cgcatatatt tggtattatt attaatgtta
    25321 aaaaaagaaa taatatttaa tggaggtctt tttaatgaaa gtaacattta atccaagtgg
    25381 tgtatgttgt agagaaatga tttttgaagt tgatgaaaat aatgtgattg ttgatgctga
    25441 gtttatagga ggatgtaatg gtaatttatc aggacttaga agcttaataa ttggccaaaa
    25501 tgctcttgaa gttgctgata aattaaatgg tattgactgt ggtggaaaag gtacttcttg
    25561 cccagaccaa ttatctaaag ctatacgtca atctatataa ttacttatat aaacatcagt
    25621 aaaattatta aaaacttatt ttatataaaa agagttgtcc attttttaga caactctttt
    25681 ttatattttt atttgtatac ttattttata aaattataat ttctttacta aagttctcac
    25741 tgtaccaatc atatataatg aacctgcact tattataata tcatcctcac ttgatgtttc
    25801 taatgtataa tttactgcat cctctatctc atgctttgat gttacatcat ctacatattt
    25861 taatactttt tctcttaata tatctgaatt tatggccctt gggttatttg gtgttgttgt
    25921 tattacctta ttaaaatgtg acaacaatat ctctaaaaca ctatcaatat ctttatcttc
    25981 taacatacct attaataagg ttaattttct acctttaaaa ttcttatcaa gtgcttttgc
    26041 caaagatttt gctccatctt cattatgtgc accatctatt ataaaaattg gattttcctt
    26101 tatcttttct attcttcctg gccatttagt atttataagt ccttttctta tagattcttc
    26161 atttatattt gctaatttat ttatgtcttt tagatatttt attacactaa ttgccaagat
    26221 agaattgttt atttgatgtt cgcctatcaa ttttatttca aggtctctat aagtttcttt
    26281 cattacagta caatcgtata tttgagaatt tatatctgat ttttttatgt ttatatcatc
    26341 aaaatcaact tctatatatt tagctttttt ctctttacaa actgacttta taacatcctt
    26401 tgcttcatca gtctggtcat atactagtac tactccattt tcctttatta ttccagcctt
    26461 ttcgtacgct attttttcta ttgtatctcc aagtatacct gtatggtcca aacttataga
    26521 tactatcaca cttacaagtg attttgttat tatatttgta gcatcatatc tgccacctaa
    26581 accaacttct aatgccacaa agtctacctt ttgttctgaa tagtaataaa atgccattgc
    26641 agtaaccact tcaaattctg tcggatatgc atagccttct tttaccataa tctctatttt
    26701 ttcttttatt aactcaatta ttctagcaac atcatcctgt ggtatgtttt gtccatttac
    26761 tcttatacgc tcagtaaaag tttctaaata tggagatgta tataaaccaa ctttatatcc
    26821 acactctctt agtatattag aaacaaaaga acacacagaa ccttttccat tagttccagc
    26881 tacatgtatt atattcaaag tttcttgtgg atttcctaat aattctaata actttccgat
    26941 attttctaat cctaatctta taccgaattt attagtttgt gatatgtact ctaatgcttc
    27001 ttcatatttc attatctaac tccccctgta ttggcatttt ctcttatgct atctaattat
    27061 agtatatttt ttacttttaa tctaccgaca aagaatacat ataatttaat accttctaca
    27121 ttaaatttag ctacaaatct ttatttataa gtttttatat ctttccacta attcagtcag
    27181 tgtatatatt gaaactaagt catattttga gatgtccata taattaaact ttatgtcaaa
    27241 tctatgctct agctttttca acagattaaa acaattatca taaaccaagc ctatctcctt
    27301 attaaaaagg ctacccttaa agagtttttc attattctct tcaatatcta agcaatccct
    27361 aacaacgtca gcaactttca taaaaagagc attttctttg tcatacaaat ccaatttaaa
    27421 gtttacaatt ctactacact catcaaaatc acaactatcc caatgatttc tagttgctaa
    27481 tgattcaagc ttatcattta aatcagatat tgttatgcct ggtttttctg ataatatctt
    27541 agctatttta ccagtaagct ttgctgataa ataactatta cattttggtg gtaatctata
    27601 ggaattattt atatcacaac ttatatatga attgctatcc ataacacatt gaacatcata
    27661 ttttttgttg taccaaaatg aatcatctcc atctaaagta aatcctctta cacctataac
    27721 attgttaaac atagctggat aacttaagtc aaaatcatta gcgagtgaac atactattat
    27781 ttttcctttt ctaaacaatt catagcaaac ttcaaataag cccttaacac tttctactcc
    27841 tatgactgat aaacttaaat taattaatct tatgttagtg tctaaaaggt atcttaatgc
    27901 ttcttcaaga acttttatat ttgtaatacc atcttttctc aaaattttta ttacaaataa
    27961 ctctacatct tcatactctt tctttattat tgatgcacaa gcagttccat gaccatcttc
    28021 atcatcaaat ttatctgata taaagatata atcatgcata cattcaaaag caattcctcc
    28081 aactaaatta tcttttaagt aatcatgttc tttgtctatt cctgtatcta atactgcaac
    28141 cttaacttta ttattcatat cacatatatt ctccattaca aaagttttta atatatctat
    28201 gttaatagtt catcttaaac tttgatttaa gttgcacaat ttatctttta aatgctatat
    28261 ttcttgctaa aaacataaaa taagtacacc atatatttaa tttatattta ttatatcaat
    28321 tattatcatt aaatggttaa atgttaagat aaaattttta gatttatatc acaatttaga
    28381 attatttgta aaaaaggaga ttatcttttt attagacaat ccccttgtat attttattaa
    28441 tatttatcta tgattaagca tcaattttat tttatacttt ttgattttaa tactatacat
    28501 ctaaatctta tttaggggga acaattattt atatgatata aaaatgctaa tttgaatgaa
    28561 cttgtcttat aatcagtttt agaaaataca ccattctaca aagtatgaat caaaaggtga
    28621 aaaaatacta aaaataataa atcaacatca attttaatca atatatgaaa aacttatacc
    28681 aagtatgtat aaaaactaat ataaatatta ttttaacaac taatacttac acctttatat
    28741 attatatcat atttcaataa ataaattgca taaaaggaaa tcttttcata gaattaaact
    28801 atttattaat tcattactat agtttcaata aactataaga tgtcgcttta atatttatat
    28861 tgtactccat taaatattaa tataattaat taaagtatgc gtagctaaat gaaacaaata
    28921 tctatagagt tttataaata atcattattt taaaaaggta atcatattct aaaaatacat
    28981 ataatgcata taaaaatcaa taatagtata ttgataatca agctactaat taataatcat
    29041 gctactataa tggaacctct acatatacat gttaaaccat attaaaaatc tataaactgc
    29101 tattttgcat aataaaactg tcttaatata aataacattt tatatattaa gacagtttca
    29161 atcaatagcc ctgtgatgac attaaatctt ttttacgata ttttcaatta cctttttaaa
    29221 attaatacat tatatcacat aacaagcttg ttaatgctac ttttaaatct ttaagtctat
    29281 acttacttat aggtataaat tgttcattaa tagtaatcat attatcccta agatcttcta
    29341 ttcttcttaa attaacaata aaacttgtat gacatctaaa aaagccattt tcacacagta
    29401 atttttctgc ttgtttcatg ctcatattag ctttataatc tctacctatt gtatgtacga
    29461 ctaaatctct ctttacagtt tcaacatata aaatagaatc tatcagtatt ctattaaatc
    29521 cttttttact atttaaaact atataacgct ccttctttct ttgaaggtta tcaatacaaa
    29581 gatttacacc cattgcaaag ttactatact ctataggctt tactaaatat ctataagcac
    29641 gaacctcata accttggggg gcatactctg aaaaagccgt tgtaaatata atttctactt
    29701 tttcatcaaa ctttcttatt tttttagcca cctcaattcc attgatatct ttcatttgga
    29761 tatctaaaaa tataatatca attttttctg ggtatttgga tattaaatct tctccacagg
    29821 aaaattccag tatttgataa tttagacatc tttcagacaa aagtttttct gtaaactctt
    29881 ttagtatgct tctttgtatt ttttcgtcat cacatataac taccctgaac ataatatcac
    29941 ctccaaatct aaaatatcat ttagtttact ttatttcaat ttccaaactg tactcactag
    30001 ctttcaaatt taaatttctt tataaattta aattgtcgat taaactactt atagaaattc
    30061 tctttaatat ttaaacttaa attacgataa attcctatac ttttctagat atattatgta
    30121 aaa
//
LOCUS       DAYAOO010000046        30065 bp    DNA     linear   BCT 12-OCT-2024
DEFINITION  TPA_asm: Clostridioides difficile isolate ST8-SSI-h139-18
            SAMN40601845-rid21577343.denovo.046, whole genome shotgun sequence.
ACCESSION   DAYAOO010000046 DAYAOO010000000
VERSION     DAYAOO010000046.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN40601845
            Sequence Read Archive: SRR28438827
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 30065)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 30065)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-MAY-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-MAY-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002157583.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002157583.1
            Genome Coverage       :: 163x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/11/2024 16:19:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 4,038
            CDSs (total)                      :: 3,963
            Genes (coding)                    :: 3,930
            CDSs (with protein)               :: 3,930
            Genes (RNA)                       :: 75
            rRNAs                             :: 6, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 60
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 33
            CDSs (without protein)            :: 33
            Pseudo Genes (ambiguous residues) :: 0 of 33
            Pseudo Genes (frameshifted)       :: 7 of 33
            Pseudo Genes (incomplete)         :: 25 of 33
            Pseudo Genes (internal stop)      :: 11 of 33
            Pseudo Genes (multiple problems)  :: 8 of 33
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..30065
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN40601845-rid21577343.denovo.046"
                     /isolate="ST8-SSI-h139-18"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Denmark"
                     /collection_date="2018"
                     /collected_by="Statens Serum Institute"
     gene            156..2180
                     /locus_tag="ACGI5H_002275"
     CDS             156..2180
                     /locus_tag="ACGI5H_002275"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009899983.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0008134 - transcription factor binding
                     [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sigma 54-interacting transcriptional regulator"
                     /protein_id="HFG9697978.1"
                     /translation="MDKKKLILITYDKLNSDHYKEELTNFFGDEIIIETQNILDGIKE
                     NLEGDVVLSLSPLTSNFLIKHFKEDIEIIHGTKALSKLGYEKMMKLPPGTKSLLMTTN
                     KTSAFEMATYLYKIGINHIDFVPTYPDCDEIYDLDTAITPGQIRFIPKYIKNIVDLGW
                     RKISLDTYMSLLVVLKLKNEKFIEKLYKLSKETLSHDFLNTSLDNISKLKTILYMTID
                     EIGDGLIFFNTFNKVTFVNKSLLNMLELDEKLIKSPSLMEYMPKSFLDKITKNLNIDN
                     MIIYIDEIDKKFILSKKPFYLYKNIEGCLITLKDVNNIEILEQKIRSDSVKRGYVAKY
                     KFNNIIGNSSIIKDCIKKAKKMALTDNPILITGETGTGKEAFTQSIHNHSNRKNKPFV
                     AINCASLPSELLESELFGYEDGSFTGAKKGGKKGLFELAHTGTIFLDEIGDMPHDLQV
                     KLLRVLQEKEIRKIGGTSIIPIDVRILAATNKDLEKLIIENKFRMDLFYRISMFTLDL
                     PPLRKRLEDIPLLLESFLKELPYKNIKLDKSLLEALNSYTWMGNIRELRNCVEYMAYM
                     GSNYLTINDLPQNISSKLNNNHMSSNMSIFNDLNQYDKNICISILKSLHMKPMGRTKL
                     MKFMEYNVTEYEVRNMLEYLTRNGYLISSKGRKGSSITEKGIKIIENNII"
     gene            complement(2410..3597)
                     /locus_tag="ACGI5H_002276"
     CDS             complement(2410..3597)
                     /locus_tag="ACGI5H_002276"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861650.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3798 domain-containing protein"
                     /protein_id="HFG9697979.1"
                     /translation="MLRKITAFMLSICLIIGLTGCSLLVGKKDKEKIIDDFKVAVVTQ
                     PLSENKVQYNMVEEMAKEYEEENKIDKDKDGQTKVKQTIKHVVLPENFTSNIDSAINK
                     IVKLADDKEVQAIVVSTDQAGLLPALQKVKEKRPEIITISAPMGDDKNQLSQFVDVNL
                     GVSAEERGKVLAERSKEMGAKAFIHYASTDDLKDVNIAKRLEMIKETCKNIGLPFVQV
                     NTPNINTEEDKNKVKQFLNEDIEKQVKKYGKDINVFGVNEYMDEVILTKALELKYIVA
                     EQSNPSPIQTYPSVMGLKISEKDAQNYDKINDMISEKAKAFGMSNRLGGYPMPMDAFL
                     PSVAIYLATEMVKQDLTQEDVCDPDYLEAFTELRFGIGSEFTPLTEVLYNYQSVILSQ
                     LIY"
     gene            complement(3799..5070)
                     /gene="brnQ"
                     /locus_tag="ACGI5H_002277"
     CDS             complement(3799..5070)
                     /gene="brnQ"
                     /locus_tag="ACGI5H_002277"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004455013.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0015658 - branched-chain amino acid
                     transmembrane transporter activity [Evidence IEA];
                     GO_process: GO:0015803 - branched-chain amino acid
                     transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="branched-chain amino acid transport system II
                     carrier protein"
                     /protein_id="HFG9697980.1"
                     /translation="MRDIFIVGFALFSMFFGAGNLMFPPFLGMESGKDWLIPLIGFVV
                     ADAGIAMLVIIATARCKGSMDDVLRRAGKGLARVMSVAALACLALLVIPRTCATTYEM
                     GIMPIFGDHGPVAKAVFSIIFFGLTLAFTIRSSKVIDIIGKYLTPALLLVLFVLIVKG
                     IISPAGPMSPEHMIDKNLFGEGISQGYQTMDALGAASMATIMLMSIIAKGYTSDKDQI
                     GMTIKAGFVACVFLAVVYGGLTYLGATVSTLYDTSIPQASLLVEITSILLYGQVGKVI
                     LGVIVALACLTTSTGLTASISTYFEGISKASYKQLVIGICVASMLISNLGVDSIIAIS
                     VPILQTIYPVLLAIVVMELAGKHIKNDNAFKGAAYVTLVISLLSAINGMTGAVPFIQS
                     LPLAGLGFNWVIPAILGGIVGNFIKSNKQVA"
     gene            complement(5211..5864)
                     /locus_tag="ACGI5H_002278"
     CDS             complement(5211..5864)
                     /locus_tag="ACGI5H_002278"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893713.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pentapeptide repeat-containing protein"
                     /protein_id="HFG9697981.1"
                     /translation="MTKIIKVQKPKFTGELEIIENLEDILEDIFNDEKIFNKIIENEV
                     ISDLDSVRVSFESCIFRNVSFENCNLKKIDLLDVVFENCNLSNTFFDGGSIYRVEFKN
                     SKLIGVRFDDCILKNVLFKDVLGKYSNFSFSKFKIVSILDSNFENSVFQEVKGDNLVF
                     EYTNLKKANFNGTKLSGIDFTTNNIEGIEIGIDDIRGAIFDVSQAIDLTKLMGIIIK"
     regulatory      6193..6294
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00167"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="purine riboswitch; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="guanine and/or adenine"
                     /db_xref="RFAM:RF00167"
     gene            6367..7710
                     /locus_tag="ACGI5H_002279"
     CDS             6367..7710
                     /locus_tag="ACGI5H_002279"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421552.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_function: GO:0015205 - nucleobase transmembrane
                     transporter activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NCS2 family permease"
                     /protein_id="HFG9697982.1"
                     /translation="MVPNTNNVQPGGNNSSLSFLDKMFKFSERGSSLKTEVIGGVTTF
                     LTMAYIVFVNPAILSEAGMDKAALITVTILATAIGTLIFAILGNAPFALAPGMGLNAF
                     FTYSLVIGAGIPWQTGLGVVFLSGCVFFTLAVTGLRKTIADAIPRELAVASSAGIGLF
                     LAFVGLKNMGVIIANPDTIVSLADFTPTVLIALFALILMAILEYKKVKGGILISIVVA
                     TIISVIFGFVELPTAIISTPPSIAPVAFKLDIVGALKFSLIGPIFSFMFIDMFDSLAF
                     LITCCKQMGLEDENGEIKDLGRMLYADVSSTLIGSFLGTSTVTTFGESASGIAAGART
                     GLASIVTAALFLATLIFTPLLGIVPTYAAAPALVMVGVFMFESIKQIDFADSKIAVPA
                     FVTVLLMPLTYSISIGLCFGFISYIIMHVVAKETDKISITLWIIGLLAVVNLVLS"
     gene            7889..9253
                     /locus_tag="ACGI5H_002280"
     CDS             7889..9253
                     /locus_tag="ACGI5H_002280"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897881.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidohydrolase"
                     /protein_id="HFG9697983.1"
                     /translation="MSQLLIKNAYLITMNADREVYENGSILIENNIIKEVGKFDINIV
                     DKDAEIYDAKGKILMPGLVNTHVHLSQQLGRGLADDVVLLTWLRERIWPYESSFNYED
                     SLISSTACCVELIKSGVTTFLESGGQYVDAMVEAVDKTGLRACLAKSVMDTGDGLPEA
                     WQKTTDEEINTQLDLFHKFNNTSNERIKIWFALRTIFNTTEELLVRTKELADKYNTGI
                     HMHIAEIADEISFVKQNNGVGTVEYLDKLGVLGPNLLAAHTVWLTHKEIDLFRLHDVK
                     VSHDPGSAMKVVLGFASIPEMLEKGIPVSIGTDGAPSNNRMDLMRDMYLTSLIHKGRT
                     LNPTVVPAEEVLEMATINGAKCALLEKEIGSLEVGKKADMIILNPDTIHCLPMHNPIG
                     NIVYSMTSENVDSTICDGKWLMKERKVLVVDESELLNKVKKQASKIKDKAEVKIPSKF
                     KIIK"
     gene            complement(9431..11296)
                     /locus_tag="ACGI5H_002281"
     CDS             complement(9431..11296)
                     /locus_tag="ACGI5H_002281"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421550.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HIRAN domain-containing protein"
                     /protein_id="HFG9697984.1"
                     /translation="MENVFKRLQEFNGYDGYKESFEMNYLCIYESIPLREQVELANNL
                     VDEILNMYKSESNEIYLLEGSNSKSLICYFEIFMKKINTLVKEMIIDEKWLYKLTKEL
                     IYKSKKVEYVKLGLVLSEKYLNVENLREVVDTFSKSGEYVFYLSNTIKKLEFYNTYLF
                     NLSKKATGSIKVFAIVNMENLDSKINSYLIEDGYKDTKYERLLMNYIISIVDLNEYLE
                     KRDLDKEKINNLARLICNYLLSVEFKYIGNKLELVNRFLPTVVNYGTNFESLYSIFLI
                     AINVLKDENIECNKIEFEKEINGILLSEKWKNIYFEALRDASGKTEDIIKMSEIYDVN
                     LSFDDLLPYLNRDIRDFEVYWHISKKGTTSSRLKLLNFFEETFKIDDLIGKMKDIEKD
                     KLTQEYYDDMLFFIVLKGSKSLYPEGKNISLKGIFGNINEVRKESINILKRYREKLSL
                     EELKIVKEAYEKEKNVILKDELRRVLYESNNLKKEFVNIEKIKVDEHGKDIYLTSIAV
                     AGSRFRNREYLEKELEKSKIYYLTREKDNLYDEKAIKIVGETGYVIGYVPRKENYILS
                     NLLDGGKLLYCRVTEYNLYEDCIYANVYLSYKDVIETVENSLKMVLDKSRIKLIN"
     gene            complement(11532..12749)
                     /locus_tag="ACGI5H_002282"
     CDS             complement(11532..12749)
                     /locus_tag="ACGI5H_002282"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004455016.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HFG9697985.1"
                     /translation="MNNKKYYPTAIALYFSYFLLGIGISILGQYKPEFSSMWGAKTLS
                     DGTLDVSIVLAVIAALGLGRLISYPFAGPISDKYGRKVSGLIGNFLHAIFFVGIVFSP
                     NFYIAYVFAIIGGAANSFLDTCVTPSCMEIFASLGTIANMFTKFTIALAQFLLPFIIG
                     FVAANSISFKVIFIVTAILIVVDAFLIAVLPFPPANNVIDNKGKTVKSEKMKFTPTSI
                     ALVCIGFTCTSTFVLWLNCNQELGKLYGMADPTKIQSFYSMGVICAVLITSLLIKKYI
                     KPIRILVIYPIIALLMLLVVYFVQTPTICMLGGFVIGYSAAGGVLKLTTSTANEMFPT
                     NKGKITSIVMIASSIANYVILNIAGIITKSGGVNGPKYVVLFNVAITFVGILLALFVN
                     MRYEKEKVYDYDV"
     gene            complement(12949..13812)
                     /gene="aroE"
                     /locus_tag="ACGI5H_002283"
     CDS             complement(12949..13812)
                     /gene="aroE"
                     /locus_tag="ACGI5H_002283"
                     /EC_number="1.1.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004455017.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004764 - shikimate 3-dehydrogenase
                     (NADP+) activity [Evidence IEA];
                     GO_function: GO:0050661 - NADP binding [Evidence IEA];
                     GO_process: GO:0019632 - shikimate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="shikimate dehydrogenase"
                     /protein_id="HFG9697986.1"
                     /translation="MEISGRTGLFALIGTPVGHSKSPVMYNYSFKKLDLDYRYLAFDI
                     TVDKVKEALLAIKTFNIKGANVTMPCKSAVTEYMDELSPAARIIGACNTIVNDNGKLV
                     GHITDGVGYVRNLKENGVEVKGKKITIMGAGGAATAIQVQCALDGAREISIFNPKDDF
                     YKRAEQTVENIKKDVPECVVNLYDLEDTNKLYEEIQSSDILTNATLIGMKPYDNETNI
                     KDTSVLRKDLVVTDVVYNPKKTKMIEDAEANGCKAIGGLGMLLYQGAEAFNLYTGLEM
                     PVEEVNELCFK"
     gene            complement(13894..15816)
                     /locus_tag="ACGI5H_002284"
     CDS             complement(13894..15816)
                     /locus_tag="ACGI5H_002284"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890951.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-dependent oxidoreductase"
                     /protein_id="HFG9697987.1"
                     /translation="MKISSMFTPIRIGSMTVPNRFVVPPMGNNFANTDGTLSETSKAY
                     YLERALGGFGLITIESSVVDKKAKGGPRKPCLYDDSTIDSFKNVIDACHDAGSKVSIQ
                     LQHAGSEGNEKVAGHPLKAASAIPASNGRNTPLAITTEEIYELIESYGDAALRAQKAG
                     ADAVEVHCAHGYLVSSFISQRTNKRVDEFGGCFENRMRLPRLIIENIRKKVGNSLAIL
                     CRINSTDDVPGGIDVHDSSVIAAYLEDCGIDGLHVSRSIHIHDEYMWAPTTLHAGFSA
                     ELVTEIKKAVSIPVITVGRYTEPQFAELMVRQGRCDLVAFGRQSLADPEMPNKAKNGK
                     LDEMIPCIACLQGCVPNMFQGKPIACLANPILGHEAELKPAEISKEVLVVGGGVGGML
                     AAWVCAKRGHNVTLVEKSEVLGGQMRLAAYPPGKGDITNLVRSYISKCNQYGVKICTN
                     TEATVELIKEKSPDVVIIATGATPLVLPIPGINDSGLIHAVDLLDGKKSCGKKVLVVG
                     GGMVGCEVAAFLGEQEHEVTVIELREEVGADVISEHRKFLMNDFENYNIHTITGAKVS
                     KFYDDGVDYLLTDGTEHDLKGFDSVVLAMGSRNYDPLSEVIKEVVKETYIVGDAVKAR
                     RALDATKEAFEVALNI"
     gene            complement(15880..16728)
                     /locus_tag="ACGI5H_002285"
     CDS             complement(15880..16728)
                     /locus_tag="ACGI5H_002285"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003431459.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016853 - isomerase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sugar phosphate isomerase/epimerase family
                     protein"
                     /protein_id="HFG9697988.1"
                     /translation="MNNQKNLNIPITISSYTLGTEVSFRDRVRIAKEAGFDGIGLRAE
                     NYIDAKNAGVTDEEMIAILNEYDMKVTEVEYITQWGREEDRTEAQREKEQNVYHMAHL
                     FNVKHINCGLLEMIPEEQIITALGELCDRAGELIIGLEFMPYSGVPDLATAWRVVKGC
                     NRENAMLILDTWHWARAKQTAEDLAPVPADKIVSIQVCDVLETPYEKLRDESLHDRLA
                     PGEGYGNTEEFVKIIKEHNISPRVIGAEVISDSLISKGLSTAAETVFNATKKVLDKAW
                     SEVSPK"
     gene            17141..18022
                     /locus_tag="ACGI5H_002286"
     CDS             17141..18022
                     /locus_tag="ACGI5H_002286"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421540.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HFG9697989.1"
                     /translation="MNLYHLRYFVTLAHLEHYTKAAENLSITQPSLSHAISLLENELG
                     VALFEKEGRNIVLTKYGKIFLKDVEKSLEILDSSVKSLKITGTGEGQIDLAFLRTLGT
                     DFIPDIVHKFLKSNPAKSIDFKFHTGVTTDIIQGLKERKYDIAFCSKLEKEKGIEFIP
                     VAKQDLVLIVPYSHPLAAKDTIDLKETIPYPQIVFNQRSGLRYIIDDMFKKINQQPNI
                     VYEVEEDQVIAGLVAKNFGIAVVPNMNMLSFTKVKVIQIIHPSWERNFYLAFIKDRYL
                     PPAIKNFKNFVIKNAQL"
     gene            complement(18230..19069)
                     /locus_tag="ACGI5H_002287"
     CDS             complement(18230..19069)
                     /locus_tag="ACGI5H_002287"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004455022.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3800 domain-containing protein"
                     /protein_id="HFG9697990.1"
                     /translation="MSKIIKKKYIMFIDESGRADINHEDPFTLTGVIFEYKYAVSQGD
                     YVCSLRKEMDAFKEYCFGTSNIGIHLTDISRKSRAFEKFDDSQIKLFYDELPLFLSRL
                     ECTIISVTVDKARLKKYYAPSKEPYVVAFIHVLQNFYSFVNNETVESARIVIESRDDV
                     SNLKVQKAFFDVFNNGTIYLDIDEELRDKVKGFIIAKKEDADYREGLEIADILCNPLS
                     RARRGLIEANPKCMQYGEKNKIFKSVRNKIYTPTSVNDIRNWGFKEVPIVEPVGPWLE
                     KMR"
     gene            complement(19248..21182)
                     /locus_tag="ACGI5H_002288"
     CDS             complement(19248..21182)
                     /locus_tag="ACGI5H_002288"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861655.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall-binding protein Cwp22"
                     /protein_id="HFG9697991.1"
                     /translation="MKKSLKKYLVLALTLVLVFACGVPESSAASKHVIIVNSRKNTLG
                     YFVNNKLVKEFRVATGKKGSETPTGKTKVVNKIKNRPYYKGNIPGGSPRNPLGDRWMG
                     LALKGTYGDTYGIHGNNNESSIGKHISGGCIRMHNKDVRWLFDQVPVGSDVIIDYSND
                     SYVKIAAKYKINLNQTGWKTENGKKYYVKSDGTYQKNSWLKVNGKMYYFDASGVMQTG
                     WKTINNKKYYLGTDGARVSGWKVIDGKTYYFNSDGVMQTGWQEKNGKKYYLGSDGLAV
                     TGWQEIDGNKYYFDKTGIMQTGWQQIDGKSYYLDKDGKMLTGSQKIDGKDYTFNEDGT
                     INPTWDTIIGANRFDTAKKISSVGNWNADSSDTVILVNGNAIADGITATPLASSYDST
                     ILLTNTANLPTETVEEMKLLAPKTVILIGGENAISSKLEQEIKTTFNTETKRIAGQDR
                     YQTATRIAEELGNREEIKTAYMVSGNGEADALSVASKAGEEKQPIILVNKDGITEESY
                     KWLTERKLENAYFIGGPSAINDSVIAKMNDITTEDISGNRIYGDSRVDTNAKVIEKFY
                     GDTDLQAVLVSKSDALVDALSAGPLAVKLHSPIVLMDNSGLSSEQQRVFANKKVETPY
                     QIGGGVSYIVMDKLMDILAK"
     gene            complement(21294..22307)
                     /gene="galE"
                     /locus_tag="ACGI5H_002289"
     CDS             complement(21294..22307)
                     /gene="galE"
                     /locus_tag="ACGI5H_002289"
                     /EC_number="5.1.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861656.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003978 - UDP-glucose 4-epimerase activity
                     [Evidence IEA];
                     GO_process: GO:0006012 - galactose metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-glucose 4-epimerase GalE"
                     /protein_id="HFG9697992.1"
                     /translation="MAVLVAGGAGYIGSHTAIELLESGYEVVIVDNLSNSNSIVVDRI
                     KELSKKPVKFYNIDIRNKDEMHVVFKENNIESIIHFAALKAVGESVEKPIEYYSNNLI
                     STLNLFELMREYGVKKFVFSSSATVYGDPHTCPILEDFPLSVTNPYGRTKLMIEQMLV
                     DISKADKSLDIALLRYFNPVGAHKSGRIGEEPNGVPSNLMPYITKIAVGKLKELSVYG
                     NDYPTHDGTGVRDYIHVLDLAAGHVKALQKLEENPGLVVYNLGTGKGYSVLDLVKAFS
                     KASGKEIPYKIVGRRAGDVAMCYADSSKAEKELGWKAKYELEEMCEDSWRWQSMNPNG
                     YEE"
     gene            complement(22331..23206)
                     /gene="galU"
                     /locus_tag="ACGI5H_002290"
     CDS             complement(22331..23206)
                     /gene="galU"
                     /locus_tag="ACGI5H_002290"
                     /EC_number="2.7.7.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009906073.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003983 - UTP:glucose-1-phosphate
                     uridylyltransferase activity [Evidence IEA];
                     GO_process: GO:0006011 - UDP-glucose metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="UTP--glucose-1-phosphate uridylyltransferase
                     GalU"
                     /protein_id="HFG9697993.1"
                     /translation="MQMTVKKAIIPAAGLGTRFLPATKSQPKEMLPIVDKPTLQYIIE
                     EAIESGIEEILIITGRNKKSIEDHFDKSVELELELEQKGKTEMLEMVRDISNMVNIHY
                     IRQKEPKGLGHAIYCAKSFIGDEPFAVLLGDDIVDSDVPCLKQLIDTYNEYKTTVLGV
                     QKIAKEDTNKYGILDVKHIEDRVYKVKDMVEKPAIEEAPSDIAILGRYIITPAIFSIL
                     EKQTPGKGGEIQLTDALQTLGKQEAIYAYNFEGRRYDVGDKIGFLEATIDFALKRENL
                     KDDLMDYMRKKVSEK"
     gene            complement(23398..23718)
                     /locus_tag="ACGI5H_002291"
     CDS             complement(23398..23718)
                     /locus_tag="ACGI5H_002291"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421530.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9697994.1"
                     /translation="MSSKYNVWTFNYEFLGLDSGDEKNNEVYYEIDLDEILNENYIDE
                     DIDSGLDSDGNSILGELISEMDIDEDVSVDMTYQELEVDLEDLDSYLDEDIDSDIKGI
                     LDEI"
     gene            complement(23708..25699)
                     /locus_tag="ACGI5H_002292"
     CDS             complement(23708..25699)
                     /locus_tag="ACGI5H_002292"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728664.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9697995.1"
                     /translation="MLKLGEKIIYELSDGFELSGISRYSKEYKKLHITNLGNIIISKS
                     DEVNEDTGVKYIYSFSDNKEKLEAVLEDSQIIVYGNNLPFYIKSENSSKNVTANLTMK
                     ITLDEYDLICKSQREFIFYLKDNMTILSLDDNKFYMGGINKDNEKFIFISGKNRFEIN
                     FDDIERYILEDKRVSLKGYFHMEREGIIVRSVSIFNNNIDSVVPSDLNERVKDNQKIG
                     NLPKDCEIVFCKISGNIDGFDYKNTNMLLVKYQDQLIFINKKSKKTIVKSAKDNCSKL
                     NLGEDIILYDNKNVFNLHINDKNREIMQIDDLKDIENEIVGYTLKHAPFFIQEDFDSL
                     TILKSFQKEIISIKNSDIKDIVINKELENENSNFVETEIKFNNQKVLLNLSKSMVQKL
                     MQDVFIYAKQPLLKENSIEVIYKNWSKAMNDMIIFNFFGNIYYMKSEFDKILEKELND
                     EIRIEVINSLYKQIQEQRNNLDLLSAYMPRILENQEIDLFEKYNTKLDVQVFKQIKNL
                     LSDLSYNISSYLNEVEKSLDNIIFVISGEDKKKYNYRMLKESESASLDVFLKQAISRL
                     NHLVENMYPYYVDETSREMFKLFELLWKNYRNIDDDSIKEILFERITNTYVFKQLTLN
                     NSTKERRKDIIEKIYNSVDYGTNKLDENMFFTGGIKYVK"
     gene            complement(25822..28365)
                     /locus_tag="ACGI5H_002293"
     CDS             complement(25822..28365)
                     /locus_tag="ACGI5H_002293"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012816330.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0042834 - peptidoglycan binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="SPOR domain-containing protein"
                     /protein_id="HFG9697996.1"
                     /translation="MKVLSENNIIRNTVLNVTASFLKQESKINEKLDGVLEKKFEKVE
                     FNEAKYAELLKFNILFYKTLARNTEPLIGKWIVDKYIPEIDELEKDLELTTAKCRKYV
                     NKAMKEGLDSLKANDLNSFLAYDKMELSERRRRLEKDYKVLNLYKDLLNISLRKISLE
                     KKECGDLFLKNQADAKRELKREIIFCVNKILASNKDVVPNNVEENNEQNKVEIKATEI
                     EDLQLGKDNSENDMLLNEIKNSKVKHESKSNDIESKFIDKLNSLNNESISQTIHNEYK
                     KLCGLEELHSVEAYGFGKEIIKDFACATVVLEFLKRRNRDLIEGAMRLTIIGEFGPEN
                     FKEFVDYVIKNKTEISEDTWNKAQNLIKDNYSELENHEIASKRTRRNKDIDIEEYIYM
                     IKNADKDICFRSSISIEDDAEEGTKEEVDSNNQDIGDVVEDKDTTDKEYDSNKEDIIE
                     PENKKSKKKAKLFGFIKKDNEEAEQEEENLNDISPDIILDKPVENHQVKSEEIEQNEL
                     KEIKQEEPSQHIEEERSVKIEKPINNNLDEKVSSNNESKLEKESKNLEDKKAKEIKEE
                     KLENEKSVVIPIKKKENSNKKSKNSSKDKYRENKKEMKNYVSDKEDSLDDEEVVSKKS
                     RLKETIIAVVIVVIVGVGYFITVGNNKKNDKENIPKSSTQQQANNKLTEEEKKAQAEK
                     EKKEAEEKAKAEKEAQEKAQAEKKAKEMEAYKDGKGVYYTVYAGSLKVEKTAKETAKE
                     YEAKGISSTIIQENGYYKIKIGDYSQYGEAQEKCNELAKKSIDTYIAMYDKYYDYKLE
                     ELKESAPSLSAEELKQKYEDLRSELKNKSGYREYVKHLDKLYEEIVEGA"
     gene            complement(28643..28977)
                     /gene="rnpB"
                     /locus_tag="ACGI5H_002294"
     ncRNA           complement(28643..28977)
                     /ncRNA_class="RNase_P_RNA"
                     /gene="rnpB"
                     /locus_tag="ACGI5H_002294"
                     /product="RNase P RNA component class A"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00010"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00010"
     gene            29109..29786
                     /gene="srtB"
                     /locus_tag="ACGI5H_002295"
     CDS             29109..29786
                     /gene="srtB"
                     /locus_tag="ACGI5H_002295"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903304.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sortase SrtB"
                     /protein_id="HFG9697997.1"
                     /translation="MKKLYRIVINIILVLVILYSGFNIYSKLTKYNHDTKISSELQKK
                     EYKKEDLSKINSDFKFWLSVENTNINYPVVQSKDNSYYLDKDFYKKDSISGTLFMDYR
                     NKSIDDKNIIIYGHNMKNKTMFNNLNKFKDADFFKKNNKIKITLNGKEFLYDVFSAYI
                     VESDYDYLKTNFNNESDYQNYINDITSKSLYKSPIKVNSNDKIVTLSTCTYEFDDARM
                     VIHGRLI"
     gene            complement(29946..30020)
                     /locus_tag="ACGI5H_002296"
     tRNA            complement(29946..30020)
                     /locus_tag="ACGI5H_002296"
                     /product="tRNA-Thr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(29986..29988),aa:Thr,seq:tgt)
BASE COUNT         9928 a         5094 c         3424 g        11619 t
ORIGIN      
        1 aataatttca aaataggttt ttataggata aaatcctaaa aaaacctatt atttaatcaa
       61 atatataaat ttatactact atttgttgta taatataact tgccttatac tttaaatact
      121 ttaaaaataa atactatttt gttaggagaa ataaaatgga taaaaagaag ttaatcctta
      181 taacatatga taaattgaat agtgaccact acaaagaaga attaacaaac ttttttggag
      241 acgaaataat catagaaaca caaaatatac ttgatggaat aaaagaaaat ttagagggag
      301 atgtagtgct ttctctatca cctttaacta gtaatttttt aataaaacat tttaaggaag
      361 atattgaaat tattcatgga acgaaagcac tttcaaaact tggatatgaa aaaatgatga
      421 aactgcctcc aggtacaaaa tcgttactta tgacaaccaa taaaacttca gcatttgaga
      481 tggctactta tctatataaa attggtataa atcatataga ttttgtaccg acatatccag
      541 attgtgatga aatatatgat ttagatacag ctataacacc aggtcagatt agatttatac
      601 caaaatacat aaaaaatatt gttgatttag gttggagaaa aatctcatta gatacatata
      661 tgtcattatt agtagtatta aaactaaaaa atgagaaatt tatagaaaaa ttatacaaat
      721 tgtccaagga gacactaagt catgatttct taaatacatc attagataat atatctaaat
      781 taaaaactat actttacatg accattgatg aaataggtga tggtctaata tttttcaata
      841 cctttaataa ggttactttt gtaaataagt ctttacttaa tatgttggaa ctagatgaaa
      901 aacttataaa atcaccttcc ttaatggaat atatgccaaa gagtttctta gataaaatta
      961 caaagaactt aaatatagat aatatgatta tatacataga cgaaatagat aaaaaattca
     1021 tactttctaa aaaaccattt tatctttata aaaatataga gggttgctta attacattaa
     1081 aagatgtaaa caatatagaa atattagaac aaaaaataag aagtgattct gtcaaaagag
     1141 gttatgtagc taaatataaa tttaataata ttattggaaa tagttctatt ataaaagatt
     1201 gtattaaaaa ggcaaaaaaa atggctctta cagataatcc tatattaata acaggtgaaa
     1261 caggaacagg taaagaagcc tttactcagt caatacacaa tcattcaaat agaaaaaata
     1321 aaccttttgt agcaataaat tgtgcttcat taccaagtga attacttgaa agtgaactat
     1381 ttggatatga agatggttct tttactggag caaaaaaagg tggaaaaaaa ggattattcg
     1441 aattagctca tactggcact atatttttag atgagatagg agatatgcca catgatttac
     1501 aggttaaact tttaagagtc ttacaagaaa aagaaattag aaaaattggt ggtacaagta
     1561 ttattccaat tgatgtgaga atattagctg ccacaaataa agatttagag aaattaatta
     1621 tagaaaataa atttaggatg gatttatttt ataggataag tatgttcact ttagatttac
     1681 ctcctcttag aaagagatta gaagatatac ctcttctttt agaatcattt ttaaaagaac
     1741 ttccctataa aaacataaaa ctcgataaga gtcttttaga agctttaaat tcatacactt
     1801 ggatggggaa tattagagaa ctgagaaatt gtgttgaata tatggcttac atgggttcca
     1861 attatcttac aataaatgat ttacctcaaa acatatcttc aaaattaaat aataatcata
     1921 tgtcaagtaa tatgtccata ttcaatgatt taaaccaata tgacaaaaac atatgcattt
     1981 ctatcctaaa atcattgcac atgaaaccaa tggggaggac aaagttaatg aaatttatgg
     2041 aatataatgt cacagaatac gaagtaagaa atatgctaga atatttgaca cgcaatggat
     2101 acttaatttc tagtaaggga agaaaaggct catcaataac tgagaaaggc ataaaaataa
     2161 tagaaaataa tataatttaa acctatagta attcatcttt actttatcaa aatttatata
     2221 taattataat tttttatttt tctataaatt ttttataaaa taataaaact tatttatatt
     2281 aaaaacgaag ctatctcaac atatggataa gcttcttttt aattgttaaa aagataaaaa
     2341 tatatttgat ttaacagaaa aagagtgcct cataaactaa aaagttcatt ttgagacacg
     2401 tccttaatat taataaatta attggcttaa aattactgat tgataattat aaagtacctc
     2461 tgttaaagga gtaaattctg aaccgattcc aaatcttaat tctgtaaacg cctctaaata
     2521 atctgggtca catacatctt cttgtgttaa atcttgtttc accatttcag tagcaagata
     2581 aattgctact gatggtagaa aagcatccat tggcatagga tatccaccaa gtctatttga
     2641 catgccaaaa gccttagcct tttcacttat catgtcgttt attttatcat aattttgagc
     2701 atctttttca gatattttta gacccataac actaggatat gtttgtattg gtgatggatt
     2761 gctttgctct gcaactatat actttaattc taaagcctta gtcaatataa cttcatccat
     2821 atactcattt acaccaaata catttatatc ttttccatat tttttaactt gtttttcaat
     2881 atcttcattt aaaaactgct taactttgtt tttgtcttct tcagtattta tatttggagt
     2941 attaacttgt acaaatggca atcctatatt tttgcaagtc tctttaatca tttctaatct
     3001 tttggctata ttaacatctt tcaaatcatc tgtagaggca taatgaataa aagcttttgc
     3061 tcccatttct tttgaacgtt cagctaatac ttttcctctt tcctctgcac taacccctag
     3121 attcacatca acaaattggc ttaattggtt tttatcatct cccatagggg cagaaatagt
     3181 tattatttct ggacgctttt cctttacctt ttgtaaagca ggtaaaagcc ctgcttggtc
     3241 agttgaaact acaatagcct gaacttcttt atcgtcagcc aactttacta tcttattaat
     3301 agcactgtct atattagaag taaaattctc tggcaataca acatgcttta tagtttgttt
     3361 aactttagtt tgaccatctt tgtctttatc aattttattc tcttcctcat attcttttgc
     3421 catctcttcc accatattgt attgtacttt attttcagat aatggttgag ttaccactgc
     3481 aactttaaaa tcatctataa ttttctcttt atctttcttg cctacaagta aactacaacc
     3541 tgtaagtcca ataattaaac atatggatag cataaatgct gttatttttc taagcattaa
     3601 ttaaaacctc ctaaatttgt acattcttat cactattact aattttatca tacttcaaag
     3661 aaaaattata ttataaaaaa ttatatacat gctattataa tccaatctaa aaagtactat
     3721 gggtagatta ggtttagatt aaacctaccc atagtactaa aaattaatat attataaaat
     3781 taaattaatt acaaattatt atgctacttg tttgttgctt tttataaagt taccaactat
     3841 tccacccaat atagctggta ttacccagtt aaagcccaaa cctgcaagtg gcaagctttg
     3901 tataaatgga acagctcctg tcattccatt tatagctgat aataaactaa tcactaatgt
     3961 aacatatgct gcacctttaa aagcattatc attctttata tgtttaccag ccaactccat
     4021 aacaactatt gctaataaaa caggatatat agtttgtagg attggaactg atatggctat
     4081 tatagaatca acacctaaat ttgatataag catactagct acacatatac ctataaccag
     4141 ttgtttataa ctcgccttac ttattccttc aaaataagtt gatattgatg ctgttaaacc
     4201 tgtagaagta gtcagacagg caagtgccac aattacacct aaaattacct ttcctacttg
     4261 accatataac aatatactag ttatttcaac taataaagat gcttgaggta tactagtatc
     4321 atataaagtt gaaactgttg cacctaaata agtaagacca ccatatacta ctgctagaaa
     4381 tacacaggct acaaaaccag ctttaatagt cattcctatt tggtctttat ctgatgtata
     4441 tcctttagct attatagaca tcaacattat agttgccata gatgctgcac ctagagcgtc
     4501 cattgtttga taaccttgtg atataccttc accaaataga tttttatcta tcatatgctc
     4561 aggactcata ggtcctgctg gagaaattat accctttact attaaaacaa ataatactaa
     4621 taataacgct ggagttaaat acttacctat tatgtctata accttagaag acctaatagt
     4681 aaatgctaaa gttagcccaa agaagattat tgaaaataca gctttagcta ctggaccatg
     4741 gtctccaaat ataggcataa tacccatttc atatgttgtt gcgcaagttc ttggtattac
     4801 aagaagtgct aaacatgcta gagcagctac actcattact cttgctaacc ctttaccagc
     4861 tctcctaagt acatcatcca tgcttccctt acatcttgct gttgctataa taacaagcat
     4921 tgctatacca gcatctgcaa caacaaatcc aataagagga attaaccagt ctttgccgga
     4981 ttccatccct aaaaatggag gaaacataag atttcctgca ccaaagaaca tagaaaataa
     5041 agcaaaacca actataaaaa tatctctcat ctgcttactc acactaaatt accccctttg
     5101 aaaatatttt gaatattaag ataatcttac tttattttca gaaaaatgtc aatctggtaa
     5161 aaattcacac attgttaacg ttttcccaat ttattttatg aatatttttt tcattttatg
     5221 ataattccca tcaatttcgt taaatcaatt gcttgtgaca catcaaaaat tgctcctcta
     5281 atatcatcta taccaatctc aattccctca atattattag tagtaaaatc tatgccagaa
     5341 agtttagttc cattaaagtt tgcttttttt aaatttgtat actcaaatac tagattgtca
     5401 ccttttactt cttgaaatac agaattttca aaatttgaat ctaagataga aactatctta
     5461 aatttagaga atgaaaagtt agaatactta cctaaaacat ccttgaacaa aacgttttta
     5521 agtatacaat catcaaatct aactcctatc aatttactat ttttaaattc aactctgtat
     5581 atacttcctc catcaaaaaa tgtatttgat aaattgcagt tttcaaatac cacatcaagt
     5641 aaatcaatct tttttaaatt acaattttca aaagacacat ttctaaatat acaagattca
     5701 aagctaactc ttacagaatc taaatcactt ataacttcat tttctataat tttattaaat
     5761 attttttcat cattaaatat atcttcaagt atatcttcaa gattttcaat aatttctaat
     5821 tctcctgtaa atttaggttt ttgcacttta ataattttag tcattttccc ctccactata
     5881 aattatatta tttttgatat tatttttttt aatatattaa cttaatatac atatttgata
     5941 tattaaaaag tttttacgaa atatccatgt attcagtact tttataatta tatcacaaac
     6001 tcatttataa taaacttcca ttaatagtat aaaacaagtt agaataattg acattatact
     6061 catacatatt caattattgg aaaaagtaat ttttttcaat aaataacctt aattttttat
     6121 aaaatcgaca aaaaaacgaa taattttatt atatttattg taaataatac aatattacga
     6181 tataatacaa cagaaaaaca aatagaaaat gttcatataa tattagtaat acggtctaat
     6241 agtttctaca aactcacctt aaatgggttt tctatgaata gaatgtcaac tctgaatata
     6301 tgttctattc tatctatatg aatatatatt tttttgttta tatcttaaag ttttttggag
     6361 gtaaaaatgg taccaaacac taacaatgta caaccaggtg gaaataattc atcattaagc
     6421 tttttagaca aaatgtttaa atttagcgaa cgtggctcta gccttaaaac agaagtaata
     6481 ggtggagtta ctacattctt aacaatggca tacatagttt tcgtaaatcc agcaatatta
     6541 tctgaagctg gaatggataa agccgccctt ataacagtta ccatactagc tacagccatt
     6601 ggtacactta tatttgcgat tttaggaaat gcaccatttg ctctagctcc tggtatggga
     6661 ttaaatgcat ttttcacata ctctttggtt ataggtgcag gaatcccatg gcaaacaggt
     6721 cttggggtag tttttctatc tggatgtgtc ttctttacac tcgcagtaac aggtcttcga
     6781 aagacaattg cagacgcaat tcctagagaa ttggcagtag catcttcagc aggtataggt
     6841 cttttccttg cttttgttgg tttaaaaaat atgggtgtta taatagctaa tccagatact
     6901 atagtttcac ttgcagattt tacaccaaca gttttaatag ccctttttgc tcttatctta
     6961 atggcaatac tagaatataa aaaagttaaa ggtggaatat tgataagtat agtagttgca
     7021 acaataatat ctgttatatt tggatttgtg gagttgccaa cagcaataat ctcaacacct
     7081 cctagtatag caccagttgc ttttaaatta gatattgtag gtgcattgaa attctcatta
     7141 attggaccta tattctcttt catgtttata gacatgtttg attcattagc atttcttatt
     7201 acttgttgta aacaaatggg tcttgaagat gagaatggtg aaataaaaga tttaggaaga
     7261 atgttatatg cagatgtttc ttctacttta ataggctcat tcttaggaac tagtactgtt
     7321 acaacatttg gagaatctgc ttctggtatt gcagcaggtg caagaacagg acttgcttca
     7381 atagtaacag cagcattatt cttagctaca cttatattta caccattact tggtatagtt
     7441 cctacttacg ctgcagctcc tgcacttgta atggttggtg tgtttatgtt tgaaagcata
     7501 aaacagattg attttgctga tagcaaaata gctgtacctg cttttgttac agttttattg
     7561 atgcctttaa cttatagtat aagtattggt ttatgctttg gatttatttc atatataata
     7621 atgcatgtag tagctaaaga aactgataaa atcagtatta cactttggat tataggttta
     7681 cttgcagttg taaacttagt tctaagttaa tatttttaaa tagttctagg tcaatatttt
     7741 aaattatata gaataaaatc ttatttattt taaatttata aatagcaaaa tcactttata
     7801 tgtaaattga ttttgctatt aactttgtat agaaaattta ttatcataat atatagatat
     7861 aaaaatatat agaaaaggag tggtgtttat gtcacaatta cttataaaaa atgcatatct
     7921 aattactatg aatgcagata gagaggtata tgaaaatgga agcatactta ttgaaaataa
     7981 tattataaaa gaggttggta agtttgatat taatattgta gataaagatg cagagatata
     8041 tgatgctaaa ggaaaaatac taatgccagg gctagtcaat actcatgttc acttatctca
     8101 acaattagga cgtggtcttg cagatgatgt tgtactttta acttggctta gagaaagaat
     8161 ttggccatac gaaagtagct tcaattatga agattccttg atttcatcta ctgcatgttg
     8221 tgttgaattg ataaaatctg gtgtcactac atttttagaa tctggtggtc aatatgtaga
     8281 tgctatggtt gaagctgttg ataaaactgg acttagagcc tgtttagcta aatcagttat
     8341 ggatacagga gatggtcttc ctgaggcatg gcaaaaaact actgatgagg aaatcaacac
     8401 tcaattagac ttattccata agtttaataa tacatctaat gagagaatta aaatatggtt
     8461 tgcattaaga actattttta atacaactga agaattactt gttagaacta aagaactagc
     8521 tgataaatac aatacaggta tacatatgca tattgctgaa atagctgatg aaatttcatt
     8581 tgtaaagcaa aacaatggag ttggaacagt tgaatacctt gataaactag gtgtattagg
     8641 accaaatctt ttagctgctc atacagtttg gcttactcat aaggaaattg atttatttag
     8701 attacatgat gtaaaagttt ctcatgaccc aggttcagct atgaaagtgg ttctagggtt
     8761 tgcatcaatt cctgaaatgt tagaaaaagg aatacctgtt tcaattggta ctgatggagc
     8821 tccttcaaat aatagaatgg accttatgag ggacatgtat cttacatcac taatacataa
     8881 aggaagaact ttaaacccaa ctgtcgtacc agctgaagaa gtcttagaaa tggctactat
     8941 aaatggagca aaatgtgctt tactagaaaa agaaattggt agtcttgaag taggaaaaaa
     9001 agctgatatg attattctaa atccagatac aattcattgt ttaccaatgc ataatccaat
     9061 tggaaatata gtttattcta tgactagtga aaatgtagac tctactattt gtgatggtaa
     9121 atggttgatg aaggaaagaa aagtattagt tgtagatgaa tctgaattat taaataaagt
     9181 taaaaaacaa gcttctaaaa taaaagataa agcagaagtt aaaattccat ctaaatttaa
     9241 aattataaaa taacataaat ttcaattgtt ttgtaaatat gaatatataa atatatttat
     9301 atacatcata tatacaaaac aattgttttt ttattttata ttcattagca ttgctcataa
     9361 aatacaccat aattccagaa aaaataacca atcagttagg attacatcat ctaagcaata
     9421 tataaacgtc ttagtttata agttttattc tactcttatc taaaaccatc tttaaagagt
     9481 tttcaactgt ttcaattaca tctttataac tcaagtacac atttgcgtag atacaatctt
     9541 catataaatt atattcagtt actctacaat acagcagttt tcctccatct aataaattgc
     9601 tcaaaatata gttttctttt cttgggacat agcctatcac atatccagtt tcaccaacta
     9661 ttttaatagc tttttcatca tatagattat ctttctctct agttaaatag tatatcttac
     9721 ttttctccaa ttctttttca agatattctc tatttctaaa ccttgaacca gcaacagcta
     9781 ttgaagtcaa atagatatcc ttaccatgtt catctacttt tattttttca atatttacaa
     9841 attctttttt taaattatta ctttcatata atactcttct taattcatcc ttcaatataa
     9901 catttttttc tttttcatac gcttctttaa caatttttaa ttcttcaaga gatagtttct
     9961 ctctgtatct ttttaagata tttatggatt cttttcttac ttcatttata tttccaaata
    10021 ttccttttaa agatatattc tttccttcag gatatagtga tttacttcct ttaagcacaa
    10081 taaaaaataa catatcatca taatattctt gagtcaattt atctttttct atatctttca
    10141 tttttccaat taaatcatct attttaaacg tctcttcaaa aaaatttaat aattttaatc
    10201 tagaacttgt cgttcccttt ttagatatat gccaatatac ctcaaaatct ctaatatctc
    10261 tatttagata tggcaacaag tcatcaaaag ataagtttac atcataaatt tctgacattt
    10321 ttataatatc ttctgttttt ccactagcat ctcttaatgc ttcaaaatat atatttttcc
    10381 atttttcact gagcaagata ccatttattt ctttttcaaa ttcaatctta ttgcactcta
    10441 tattttcatc ttttaagacg tttatagcta ttaggaaaat tgaatataaa ctttcaaagt
    10501 tagtcccata atttactaca gtaggtaaaa atcgattcac taattctaat ttattaccta
    10561 tatatttaaa ttctacactt agcaagtaat tgcatataag acgtgctaaa ttatttatct
    10621 tttctttatc taaatctcgt ttttcaagat attcattcaa atctacaatt gaaataatat
    10681 agttcatcaa taatcgttcg tactttgtat ccttataacc atcttcaatt agataggaat
    10741 ttattttaga atctaaattt tccatattaa caatagcaaa tacttttatt gaacctgtag
    10801 cctttttaga taaattaaat aaatatgtat tgtaaaattc aagtttttta atagtattac
    10861 tcagataaaa tacgtattct ccagatttag aaaatgtatc tacaacttct cttaagtttt
    10921 ctacatttag atatttctca cttaaaacta accctagttt tacatactca acttttttac
    10981 tcttatatat taattcttta gttaatttat ataaccattt ctcatcaata atcatttctt
    11041 ttaccaaagt atttatcttt ttcataaaaa tttcgaaata acaaattaaa gacttagaat
    11101 tactaccctc caataaataa atttcattag attcactttt atacatattt aaaatttcat
    11161 ctactagatt atttgcaagc tctacttgtt ctcttaacgg tatactttca tatatacata
    11221 ggtaattcat ttcaaatgat tctttgtatc catcataacc attaaattcc tgcaatcgct
    11281 taaaaacatt ctccaccaaa ttatcctcct ttacatgatg taatttatat tgattatact
    11341 acttatttca tcaagtttac atttatacgc aaaaaaatat tactagaaat tgaaattcta
    11401 gtaatatcct tattattaat tatgtaaata ccctatctta taactgtaaa taatatcctt
    11461 attaatttta attactttta ataaaaatct atcctagatt tagacttctc tatgcatata
    11521 ttatactaat attagacatc ataatcatac actttttctt tttcatatct catgtttaca
    11581 aacaatgcaa gtaaaattcc aacaaatgtt attgccacat taaacaatac aacatatttt
    11641 ggtccattaa ctccccctga ttttgtaata atacctgcta tatttaaaat aacatagttt
    11701 gctatactag atgcaatcat aactatagat gttatttttc ctttattagt tggaaacatt
    11761 tcatttgcag ttgacgttgt taacttaaga acacctcctg ctgctgaata acctattaca
    11821 aatcccccta acatacaaat agttggagtt tgaacaaaat atacaactaa tagcataagt
    11881 aaagctatta taggatatat aactaatatt cttattggtt taatatattt tttaataagt
    11941 aaagaagtta ttaatactgc acatattact cccattgagt aaaaggattg aatttttgta
    12001 gggtcagcca tcccatacaa tttacccaat tcctgattac aatttaacca taatacaaat
    12061 gtagatgtac atgtaaatcc aatacaaaca agagctatac ttgttggtgt aaatttcatc
    12121 ttctctgatt taactgtttt gcctttgtta tcaataacat tattagctgg tggaaatggt
    12181 aacacagcta tcaaaaaggc atctactaca ataagaatcg ctgttactat aaaaataact
    12241 ttaaatgata ttgaatttgc tgcaacaaat ccaattataa aaggaagcaa aaattgtgct
    12301 aaagctattg taaatttagt aaacatattt gctattgttc ctaaactagc aaatatctcc
    12361 atacaagaag gagttacaca ggtatctaag aatgaatttg ctgcccctcc aattattgca
    12421 aatacatatg ctatataaaa atttggtgaa aatacaattc caacaaagaa aattgcatgt
    12481 agaaagtttc ctataagacc acttactttt cttccatact tatctgaaat aggtcctgca
    12541 aatggataag atataagtct ccctaatcct agtgcagcaa taacagctaa aacaatactt
    12601 acatccaatg ttccatctga taatgtttta gccccccaca ttgatgaaaa ttctggtttg
    12661 tattgtccta aaattgaaat tccaatacca agtaaaaaat atgaaaaata caacgctatg
    12721 gcagtaggat aatatttttt attgttcata atttttctcc cattcttgtt aatttattaa
    12781 catttttgtg tacaataaac tcatccccat aatggattta aagtatagtc agttaaagct
    12841 tcaaatttaa ctggactatg aggcaaaacc cactatgaca atttgtaatt tattattaaa
    12901 aatattgaaa tacgtatgtt ttttcattgt ttaagatatt actcttatct atttaaagca
    12961 taattcatta acttcttcta caggcatttc taatccagta tatagattaa aagcttctgc
    13021 tccttggtat aataacattc ctaatccacc aatagcctta catccattag cttcagcatc
    13081 ttcaatcatt tttgttttct taggattata aacgacatct gttactacta aatcttttct
    13141 taaaacacta gtatctttta tatttgtttc attgtcataa ggcttcatac caataagagt
    13201 tgcatttgtc aatatatcac ttgattgtat ctcctcataa agtttgtttg tatcttctaa
    13261 atcatataga ttaacaacac attctggtac atcttttttt atattctcaa ctgtttgctc
    13321 tgctctttta taaaaatcat ccttaggatt aaagatagat atttctcttg ctccatctaa
    13381 agcacattgt acttgtatag cagttgctgc accaccagca cccataattg taatcttttt
    13441 acctttaact tctaccccat tttcttttaa attacgaaca tagcctactc catctgttat
    13501 atgaccaact aactttccat tgtcatttac aattgtatta catgctccaa ttatacgagc
    13561 tgctggagaa agttcatcca tatattctgt aacagcagat ttacatggca tagtaacatt
    13621 ggctcctttt atattaaaag tttttattgc taaaagtgcc tcttttacct tatctactgt
    13681 gatatcaaag gctaaatatc tataatctaa atctaatttc ttaaaactat aattatacat
    13741 cactggtgat ttagagtgac caaccggtgt acctattaat gcaaataatc ctgttctacc
    13801 tgaaatttcc ataactataa tctcctctca atattatcat tttctttgca aataacctat
    13861 tcagttattt acaaagaaaa atttatttat tatttatata tttaatgcta cttcaaaagc
    13921 ttcttttgtt gcatctaatg ccctacgagc ttttactgca tcaccaacaa tataagtttc
    13981 ttttacaact tcttttataa cttcacttaa tgggtcgtaa ttacgagaac ccatagcaag
    14041 tactactgaa tcaaaacctt ttaaatcatg ctctgtgcca tctgtaagta aatagtcgac
    14101 accatcatca taaaatttag aaacttttgc accagtaatg gtatgtatat tataattttc
    14161 aaaatcattc ataaggaatt tacggtgttc tgaaattaca tctgcaccaa cttcttctct
    14221 aagctcaata acagtaacct catgttcttg ttctccaagg aaggctgcca cttcacatcc
    14281 aaccattcca cctccaacaa caagtacttt tttcccacaa gattttttac catcaagaag
    14341 gtctacagca tgaattaatc ctgaatcatt gattcctggt ataggaagta caagtggagt
    14401 tgctccagta gctataataa ctacatcagg tgatttctcc tttataagtt ctactgtagc
    14461 ttctgtatta gtacatattt ttacaccata ttgattacat tttgaaatat aacttctaac
    14521 taagttagta atatctcctt tccctggagg atatgcagct aaacgcattt gcccaccaag
    14581 aacttcagat ttttcaacta aagttacatt atgtcctctt ttagcacata cccatgctgc
    14641 aagcatacct ccaacacctc caccaacaac aagaacttct ttgctaattt cagctggctt
    14701 aagctctgct tcatgtccta atataggatt tgcaagacag gctataggtt tgccttggaa
    14761 catatttggt acacatcctt gtaagcatgc aatacatggt atcatttcgt ctagttttcc
    14821 atttttagct ttattaggca tttctgggtc agccaagctt tgtctaccga atgctactaa
    14881 atcacatctt ccttgtctga ccattaactc agcaaactgt ggctctgtat aacgtccaac
    14941 tgttattact ggtatactaa cagctttttt tatttcagta actaattctg cactgaatcc
    15001 agcatgtaaa gtcgtaggag cccacatata ttcatcatgt atatgtatac tacgtgaaac
    15061 atgaagtcca tctattccac aatcttctag atatgctgct attactgaac tatcgtgtac
    15121 atcaattcct cctggaacat catcagtgct gtttatacga cataatattg ctagagaatt
    15181 tcctactttt ttacgtatat tttcaatgat aagacgaggt aatctcattc tattttcaaa
    15241 acatccacca aactcatcta cacgcttatt tgttctttgt gatataaaac tactaaccag
    15301 atatccatga gcgcagtgaa cttcaacagc atctgcacca gctttttgtg cacgtaatgc
    15361 agcatctcca taagattcta taagttcata tatttcttct gttgttattg ctagtggtgt
    15421 attacgacca tttgatgcag gtattgcaga agcagctttt aatggatgtc ctgctacttt
    15481 ttcatttcct tcagaaccag catgttgtaa ttgtatagat accttcgaac ctgcatcatg
    15541 acaagcatct attacatttt taaaactatc tattgtgcta tcatcatata aacaaggctt
    15601 acgaggacct ccttttgctt ttttgtctac aacactagat tctatagtta ttaatccaaa
    15661 accacctaaa gcacgctcaa gataataagc cttagaagtt tcacttaaag taccatctgt
    15721 gtttgcaaaa ttgtttccca tagggggaac tacaaaacga tttggaactg tcattgaacc
    15781 aattcttata ggtgtaaaca tagaactaat cttcataagg ttttccttcc tttcaagttt
    15841 tatattataa tactctgtat atttttatat tatataagtt tattttggag atacttcaga
    15901 ccatgcttta tccaaaactt ttttagttgc attaaataca gtttcagcag cagtggataa
    15961 ccctttagat attagagaat cagatattac ttctgcccct atgactcttg gtgatatatt
    16021 gtgttctttt attattttca caaattcctc tgtgtttcca tatccttcac ctggagccaa
    16081 acggtcatgt agtgattcat ccctaagttt ttcataagga gtttctaaaa catcacacac
    16141 ttgaattgat actatcttat ctgctggaac aggtgcaagg tcctctgctg tctgctttgc
    16201 tctagcccag tgccaagtat ctaatataag cattgcattt tcacgattac atcctttcac
    16261 aacacgccat gcagtagcca aatctggtac accactatat ggcataaact caagacctat
    16321 aataagttca cctgctctgt cacataattc tcccaatgca gttataattt gttcttctgg
    16381 tatcatctct aataatccac aatttatatg tttaacatta aataagtgag ccatatgata
    16441 aacattttgc tctttttctc tttgagcttc cgttctatct tcttctcttc cccattgagt
    16501 tatatattct acttctgtaa ctttcatatc atattcatta agaattgcaa tcatttcttc
    16561 atctgtaaca cctgcatttt ttgcatcaat ataattttca gcacgcaatc caataccatc
    16621 aaacccagct tcttttgcaa tacgaactct atcacggaat gaaacttctg ttcccaatgt
    16681 ataagaacta attgtaattg gaatattaag atttttttga ttattcatag cttaaatttg
    16741 ccccctttat tttctttata attaatagta tttttgattt tatattttta tttatcctac
    16801 tagtagtatt attttacctt aaaaataaaa gtattttttg atttctattt atctagattt
    16861 tataaattta ttgtatcacg agactttact aataacaaat tgataatttc ctattaattc
    16921 atagattttg tttatagatt ttatttataa gataattctt gtatttttct attaggtcgt
    16981 ataaatatat ttatcttata attcagacaa aaaacgataa atttttttaa aagcttttat
    17041 tcttactcta taatcatata taataaaaat gtaaaaatat cttaaaggtt aacttctaca
    17101 aatatataaa taaaaatacc tatgaaagga tgaacaaaaa ttgaatttat atcacttacg
    17161 ctattttgtt acattggcac atttagaaca ctatacaaaa gcggcagaaa atttatctat
    17221 aacacaacca agcttaagtc atgctatttc tttactagaa aatgaacttg gggtggctct
    17281 atttgaaaaa gaaggtagaa atatagtcct tactaagtat ggaaaaatat ttttaaaaga
    17341 tgtggaaaaa tcattagaaa ttttagattc aagtgtaaaa tcattaaaaa taactggtac
    17401 tggtgaagga caaatagact tagcttttct tagaacactt ggtactgatt ttatcccaga
    17461 catagtgcac aaatttttaa aatctaatcc tgctaaatca atagatttta aatttcatac
    17521 tggtgtaact actgacatta ttcaaggtct taaagaaaga aaatatgata ttgcattttg
    17581 ttcgaaactt gaaaaagaaa agggaattga atttatacct gttgccaaac aagatttagt
    17641 actaattgta ccatatagtc atccactagc tgcaaaggat actatagatt taaaagaaac
    17701 cataccttat cctcaaatag tatttaatca gagaagtggt cttagatata taattgatga
    17761 tatgtttaaa aaaataaatc aacagcctaa tatagtctat gaagtagagg aagaccaagt
    17821 aattgctgga ttagttgcaa aaaatttcgg aattgctgta gtcccaaata tgaatatgct
    17881 tagctttaca aaagtaaaag taattcagat tattcaccca agttgggaaa gaaactttta
    17941 cttagcattt ataaaagata gatatttgcc tcctgcaatt aaaaacttta aaaactttgt
    18001 cattaaaaac gctcaattat aatttattaa taaaggggtt atttttaaat atcctctttt
    18061 attcttttta taaaataaaa aaatctatac ttttaaaagt atagattcct aactgacagt
    18121 cggcatccga gtctcagtaa ttatcgttat acaacagcaa ctggattcag ttcctgaata
    18181 actaggttac ttacattata tcagattttt taaaatttgt caattgtatc taacgcattt
    18241 tttcaagcca tggtccaaca ggctctacaa taggaacttc tttaaatccc caatttctta
    18301 tatcattcac actcgttgga gtatatattt tgtttctgac agatttgaat attttgtttt
    18361 tttctccata ttgcatacac tttggattag cttctattaa ccctcttctt gctctgctaa
    18421 gaggattaca taaaatatct gctatttcta aaccttctct atagtcagca tcttcttttt
    18481 tggcaattat aaaaccctta accttatctc ttaattcttc atctatatct aagtatattg
    18541 ttccattatt aaatacatca aaaaacgcct tttgtacttt taagtttgag acatcatccc
    18601 ttgactctat aactattcgt gcagattcta cagtttcatt atttacaaat gaataaaaat
    18661 tctgaagaac atgtataaaa gccacaacat acggttcctt tgaaggtgca taatatttct
    18721 ttaatctagc tttatctact gttactgata ttatagtaca ctctaatcta gatagaaata
    18781 aaggcaactc atcatagaat aacttaatct gtgaatcatc aaacttctca aatgctcttg
    18841 attttcttga tatatctgtc aaatgtattc ctatgttact ggttccaaaa caatactctt
    18901 taaatgcatc catttctttc ctcaaagaac atacataatc gccttgactt actgcatatt
    18961 tatattcaaa aattactcct gtcaatgtaa atgggtcttc atgatttata tcagctcttc
    19021 cactttcatc aataaacatt atatattttt tctttataat cttactcacc ctcttaacat
    19081 atgatgatag catctatatt cattttatat gagttttaaa aatattccaa gatttttata
    19141 taacttaaac ttaattttat actaaaaaat tgagatgtaa aacaatcaag cttttattga
    19201 ttgaatttca catctcaatt ataattattt ttcaatatat atttttacta ttttgcaaga
    19261 atatccatta atttatccat tactatataa gatactccgc ctcctatttg ataaggagtt
    19321 tcaacttttt tatttgcaaa tactctttgt tgctctgatg ataatcctga attatccatt
    19381 aaaactattg gtgaatgtaa ttttacagct aatggtccag ctgataaagc atctactaaa
    19441 gcatctgatt tactaactaa tacagcctgt aaatcagtat ctccatagaa tttttctatc
    19501 actttggcat tagtatctac tctactatct ccatatattc tatttcctga aatatcttca
    19561 gtagttatat cattcatttt tgctattact gaatcgttaa ttgcacttgg tccacctata
    19621 aagtatgcat tttctaattt tctttctgtt agccatttat aagattcttc tgtaattcca
    19681 tctttattga ctaatattat aggttgtttt tcttccccag ctttagaagc tacagataaa
    19741 gcatctgcct ccccatttcc agaaaccata tatgcagttt ttatttcttc tcgatttcca
    19801 agttcttcag ctattcttgt agcagtttga tatctatctt gacctgctat tctctttgtt
    19861 tctgtgttga aagtagtttt tatttcttgc tctaatttag aacttattgc attttctcca
    19921 cctatcaaga ttactgtttt aggtgctaat aacttcattt cttcaacagt ttcagttggt
    19981 aaattagctg tattagtaag tagtattgtt gagtcatagc tacttgctaa aggagttgct
    20041 gttataccat cagctattgc attaccattt actaatatta cagtatctga actatcagca
    20101 ttccagtttc caactgaact tatcttttta gctgtatcaa atctatttgc acctataatt
    20161 gtatcccatg taggatttat agttccatct tcattaaaag tataatcttt cccatctatt
    20221 ttttgagaac cagttagcat ctttccatct ttgtctaaat agtaagactt accatctatt
    20281 tgttgccatc ctgtctgcat tattcctgtt ttgtcaaagt aatacttatt accatctatt
    20341 tcttgccatc ctgttactgc taaaccatca gatcctagat agtatttctt tccattcttt
    20401 tcttgccatc ctgtttgcat tactccatct gagttaaagt aataagtttt tccgtctatt
    20461 actttccatc cagatactct tgctccatca gttcctaaat aatatttttt gttattaatt
    20521 gttttccatc ctgtttgcat tactcctgaa gcatcaaagt aatacatttt tccatttact
    20581 tttagccaac tattcttttg gtatgttcca tcagatttta cataatactt cttaccattt
    20641 tctgttttcc atcctgtttg atttagattt atcttatatt ttgccgctat ctttacatag
    20701 ctgtcgttac tataatctat aattacatct gaacctacag gaacttggtc aaataaccat
    20761 ctaacatctt tattgtgcat tcttatacat ccaccagaaa tatgctttcc tatagaactc
    20821 tcattattat ttccatgtat tccatatgta tctccataag ttccttttaa tgctaatccc
    20881 atccatctat ctcctaatgg atttcttgga cttcctccag gtatattacc tttataatat
    20941 ggtctatttt ttatcttgtt aactactttt gttttccctg ttggtgtttc tgaccccttt
    21001 ttacctgttg caactctaaa ttcttttaca agtttattat ttacaaaata tcctagagta
    21061 ttttttcttg aatttactat aatcacatgt ttactggctg cgcttgattc tggtacgcca
    21121 catgcaaata ctaaaactaa agtcagtgct agtactaaat acttttttag actttttttc
    21181 actataactt ccccctcttt tagaaacatt actacatgtg tctaattata acataaaatt
    21241 accaatacct tatatttaca aatttgttac atttatacat ataagtatgt attctactct
    21301 tcatacccat taggattcat actttgccat ctccatgaat cttcacacat ctcttcaagt
    21361 tcatacttag ctttccatcc aagctctttt tctgcctttg aagaatctgc ataacacatg
    21421 gctacatctc cagcccttct tcctacaatc ttatatggta tttcttttcc acttgcttta
    21481 gaaaatgctt ttactaaatc aagaacacta tacccctttc cagttcctaa attataaaca
    21541 acaagtcctg gattttcttc taatttttgt aatgctttta catgaccagc agctaaatct
    21601 aatacatgta tatagtctct aactccagtt ccatcatgtg ttggatagtc attaccataa
    21661 acactcaatt ccttcaattt acctactgct atttttgtta tataaggcat tagattgctc
    21721 ggaactccat ttggttcttc acctattcta ccacttttat gagcaccgac tggattaaag
    21781 tatcttaaaa gagctatatc caatgactta tctgcttttg atatatctac taacatctgc
    21841 tctatcataa gtttagttct tccatatgga ttggttacag aaagtggaaa atcctctaat
    21901 ataggacaag tatgtgggtc tccatataca gtagctgaag aactaaatac aaacttttta
    21961 acaccatatt ctctcattaa ttcaaataaa tttaaggtac ttattagatt attgctgtaa
    22021 tattcaattg gtttttctac tgattcacca actgctttta aagctgcaaa gtgtataatt
    22081 gattcaatat tattttcttt aaatacaaca tgcatttcat ctttatttct gatatcaata
    22141 ttataaaatt ttactggttt tttagataat tccttgattc tatcaaccac tattgagttg
    22201 ctattactta agttatcaac tataacaact tcataacctg attctaaaag ttctattgct
    22261 gtatggcttc ctatatatcc tgctcctcca gctactaaaa ctgccattgt aattacctct
    22321 tttctaatat ttatttttca cttacttttt ttctcatata gtccattaaa tcatctttta
    22381 aattttctct ctttagagca aagtctattg ttgcctctaa aaaaccaatt ttatctccca
    22441 catcatatct tctaccttca aagttataag cataaatagc ctcttgtttt ccaagagttt
    22501 gaagtgcatc tgtcagttgt atctctccac ctttaccagg tgtctgtttc tctaatatgc
    22561 taaatattgc aggagttatt atatatcttc caagtatagc tatatcagat ggagcttctt
    22621 caattgcagg tttttcaacc atatctttaa ctttatatac tctatcttcg atatgtttta
    22681 catccaatat accatattta ttagtatctt ctttagctat cttttgaaca cctaatacag
    22741 ttgttttata ctcattataa gtatctatta attgttttaa gcacggaaca tctgaatcta
    22801 ctatatcatc acctaataat acggcaaaag gttcatcacc tataaaactt tttgcacagt
    22861 aaattgcatg tccaagacct tttggctctt tttgtcttat ataatgaata tttaccatat
    22921 ttgatatgtc tcttaccatt tctaacatct ctgtcttacc tttttgctct agttctaact
    22981 ctaattcaac tgatttatca aaatgatctt ctatagattt tttatttcta cctgttatta
    23041 taagaatttc ttcaattccc gattctatag cttcttctat tatatactgt aaagttggtt
    23101 tatctactat aggaagcatt tctttgggct gtgattttgt tgctggtaaa aatctagttc
    23161 ctagccctgc tgctggtatt attgcttttt taactgtcat ctgcattttt tcacccttct
    23221 tcgtaaattt tctattgtac caaattaata taccatattt atactttttc ttcaaactct
    23281 atattatccc aatatttaat gctataagat aatataaggt agatgaaatt tcatctacct
    23341 ttagttttat aagttaatat tgtattgttt atattttatc caaaacttat acaggtacta
    23401 aatttcatct aagatgcctt ttatatcact atctatatct tcatctagat aagaatctaa
    23461 atcttctaag tcaacttcta gttcttgata tgtcatatca acactgacat cctcatctat
    23521 atccatttct gatattaatt ctcctaaaat actatttcca tcagaatcta aaccactatc
    23581 tatatcttca tctatatagt tttcatttaa aatttcatct aaatcaatct cgtaataaac
    23641 ttcattattt ttttcatccc ctgagtccaa tcctaagaac tcatagttaa aagtccaaac
    23701 attgtattta cttgacatac tttattcctc ctgtgaaaaa catattttca tctagtttat
    23761 tggttccata atcaacagag ttatatattt tttcaattat gtcttttctt ctttcttttg
    23821 tactattatt taatgtcaat tgtttaaata catatgtatt tgttattctc tcgaataata
    23881 tttcttttat actatcatca tcaatatttc tatagttttt ccacaataac tcaaataact
    23941 taaacatttc cctactagtt tcatctacat aataaggata catattttct actaaatggt
    24001 ttaatcttga tatggcttgt tttaaaaata catcaagact tgcactttca ctttctttta
    24061 acattctata attgtatttc ttcttatctt ctcctgaaat tacaaagatg atattgtcta
    24121 aacttttttc aacttcattt aaataactgc ttatattata tgataaatca gacaatagat
    24181 ttttaatctg cttaaacact tgtacatcaa gtttagtatt atacttttca aacaaatcta
    24241 tttcttgatt ttctaatatt cttggcatat atgctgacaa taaatctaaa ttgtttcttt
    24301 gttcttgtat ttgcttataa agtgaattta taacttctat tcttatttca tcatttaact
    24361 ctttttctaa aatcttatca aattcagatt tcatatagta aatatttcca aagaaattaa
    24421 atattatcat atcattcata gctttagacc aattcttata tatcacttca atagaatttt
    24481 ctttaagtag aggttgcttt gcatatataa atacatcttg cataagtttt tgaaccatac
    24541 ttttacttaa gtttaaaagt actttttgat tattaaattt tatttccgtt tctacaaaat
    24601 tagaattttc gttttcaagt tctttattaa ttacaatgtc ttttatatca ctatttttta
    24661 tagatatgat ttctttttga aaagacttta gaatagtcaa gctatcgaaa tcttcttgaa
    24721 taaaaaatgg agcatgtttt aatgtatatc ccactatttc attttctata tcttttaggt
    24781 catctatttg cataatttct ctatttttat catttatatg taggttaaat acatttttat
    24841 tatcatataa tattatatct tctcctaaat ttaacttaga acaattatct ttcgctgact
    24901 ttacaatagt cttcttagat ttcttattta taaaaattaa ttggtcttga tattttacta
    24961 aaagcatgtt tgtgttttta taatcaaatc catctatatt tcctgatatc ttgcagaata
    25021 ctatttcaca atctttagga agatttccta ttttttggtt atctttaact ctctcattta
    25081 aatcagatgg gactacacta tctatattgt tattaaatat agatacagac cttactataa
    25141 tcccctctct ttccatatga aagtatccct tcaatgacac tcttttatct tctaaaatgt
    25201 atctttctat atcatcaaaa tttatttcaa atctattttt cccactgata aatataaact
    25261 tctcattatc tttattaatt ccacccatat aaaacttatt gtcatctaaa cttaatatag
    25321 tcatattatc ctttagatag aatataaatt ctctttgact tttgcagatt aaatcatatt
    25381 catccaaagt tattttcata gtcaaatttg ctgtaacatt tttacttgaa ttttcacttt
    25441 ttatgtaaaa aggcaagtta tttccataga caattatttg agaatcttct aaaactgcct
    25501 ctaatttttc tttattgtct gaaaaactat atatatattt tacacctgta tcctcattaa
    25561 cttcatctga tttgctgatt attatattcc ctagatttgt tatatgaagc tttttatatt
    25621 cttttgagta tctacttatg ccactaagct caaacccatc tgaaagctca tatatgattt
    25681 tttctcctaa tttcaacata ccttcaccac ctaaacagaa ttataagtat tttataaagg
    25741 tgaataaaat gtctcaaaac aaataatatt ttttttaata ctttttattc tgagacatag
    25801 tttctccttt tttataatgc tctaagcacc ttcaactatt tcttcataaa gtttatctaa
    25861 atgtttaaca tattcacgat atccagattt gttctttaac tcacttctta aatcttcata
    25921 tttttgttta agttcttcag cactcaaaga aggagctgat tcttttaatt cttctaactt
    25981 ataatcatag tacttatcat acatagctat atatgtatca atagacttct tagctagttc
    26041 attacatttt tcttgtgctt ctccatattg agaataatca cctattttta ttttatagta
    26101 tccattttct tgaattattg ttgaagaaat acctttagct tcatattctt ttgctgtttc
    26161 ttttgctgtt ttttcaactt taagtgaacc tgcataaaca gtgtaatata cacctttacc
    26221 atctttatat gcttccattt cttttgcttt cttttcagct tgtgcttttt cttgagcctc
    26281 tttttcagct tttgcctttt cttctgcttc ttttttctct ttttcagctt gtgctttttt
    26341 ctcttcttca gttaatttat tgttagcttg ttgttgagtt gatgactttg gaatattctc
    26401 tttatcattt ttcttattgt tgcctactgt tataaaatat cctacaccaa caataaccac
    26461 tataactact gctataatag tttcttttaa tctactcttc ttagaaacaa cctcttcatc
    26521 atctaaagaa tcttctttat ctgatacata atttttcatt tctttcttgt tttctctata
    26581 tttgtcctta gaagaatttt tagatttttt attactattt tctttctttt taataggtat
    26641 tactactgat ttttcatttt ctaatttttc ttcttttatt tcttttgctt ttttatcttc
    26701 taagttttta ctttcttttt caagcttcga ttcattattt gaagatactt tttcatctaa
    26761 gttattattt attggttttt ctatttttac actacgttct tcttctatat gttgacttgg
    26821 ttcttcttgt tttatttctt tcaattcatt ttgctctatt tcttctgatt tcacttgatg
    26881 attttcaact ggtttatcta aaattatatc tggagaaata tcatttaaat tctcttcttc
    26941 ttgttcagct tcttcattgt cttttttaat aaatccaaat aatttagcct tctttttact
    27001 ctttttattt tctggttcaa ttatatcttc tttattgctg tcgtactctt tatctgtagt
    27061 atctttatct tctacaacgt cacctatatc ttgattatta ctatctactt cttctttagt
    27121 cccttcttca gcatcatctt ctattgaaat actacttcta aagcaaatat ctttatctgc
    27181 attttttatc atgtaaatgt attcttcaat atcgatatct ttatttcttc tagttctttt
    27241 tgatgcaatt tcatgatttt ctaattcact atagttatct tttattagat tctgtgcttt
    27301 attccatgta tcttcactaa tttctgtttt atttttaatt acatagtcca caaattcctt
    27361 aaaattttca ggaccaaatt ctccaattat agtcagtctc attgcacctt ctataaggtc
    27421 tctatttctt ctctttaaaa attctaatac aactgttgca caagcaaaat ctttaataat
    27481 ttctttgcca aaaccatatg cttcaacaga atgaagttct tctaatccac ataacttctt
    27541 atattcattg tgtattgttt gagatatact ttcattattt aagctattta acttatctat
    27601 aaacttcgat tctatatcat ttgattttga ttcatgtttt acttttgaat ttttaatttc
    27661 atttagtagc atgtcatttt ctgaattatc tttacctaat tgcaaatcct caatttcagt
    27721 tgcttttatt tctactttgt tttgttcgtt attctcttcc acattattag gtaccacatc
    27781 tttattacta gctaatattt tgtttacaca gaatataatt tctcttttta attctctttt
    27841 cgcatctgct tgatttttaa gaaataaatc tccacattct ttcttttcta aacttatttt
    27901 tctaagagat atattaagaa ggtctttata taggtttaaa accttataat ccttttctaa
    27961 acgtcttctt ctctctgata gttccatttt atcataagct aaaaaactat ttaaatcatt
    28021 ggcttttaga gagtctaatc cctctttcat agccttattt acatactttc tacattttgc
    28081 tgtagttaac tctaaatctt tttctaattc atctatttca ggtatgtact tatctactat
    28141 ccatttgcca ataagtggtt ctgtatttct tgctaatgtc ttataaaaca atatattaaa
    28201 ttttaaaagc tctgcatatt ttgcttcatt aaattctact ttttcaaatt tcttttccaa
    28261 aacaccatct agcttttcat ttattttaga ctcttgtttt aaaaaacttg ctgtgacatt
    28321 taaaacagtg tttcttatta tattattttc actcaaaacc ttcactcctt aaatcaatta
    28381 ttttattgta atatttacat tgtgcaaagt tgctaatttg attatgatat ctaaataatt
    28441 atttactaaa tttgctacat cttatatcat atcatattat ttacatcatt ttactttttc
    28501 tttttatatc tatcttatat tataccattt ttaatatctg tactaactta tattacaata
    28561 ttcctcaaaa ttttaaaagt agattagaca aatttacaaa taaaaaaaca tcagtttaaa
    28621 ctgatgtttt tgactatcga aataattaag caagtctata agcggagttc tgtattagat
    28681 aatcatcttt ctaggcctat tgtcaccaat aggctcaagc gacctaccta ccggagagta
    28741 cgagcagcac tctttattcc tatcttggtc ttgctccagg tggggtttac atagccaact
    28801 agtcgcctag ctgctggtga gctcttacct cgcctttcca tccttaccac aatagtggcg
    28861 gtttatttct gttgcactat ccttaggatc gctcccacta ggcgttacct agcaccctgc
    28921 tctatggagc tccgactttc ctcatgtaag attacatgcg attatctggc ttacttaata
    28981 tttattttac ttagttatgt taacacaaat tcttttacat gtcaaagtaa tattatacta
    29041 aaaatttaaa tttattcaaa aatagtgtaa tatagatata taaactacat ttaactcgag
    29101 gtgatctatt gaaaaaatta tatagaatag taattaacat tatactagta ttagtaatac
    29161 tttacagtgg atttaatata tactcaaaac ttaccaaata caatcatgat actaaaatat
    29221 cctcagaact tcaaaaaaaa gaatataaaa aagaggattt atcaaagatt aacagtgatt
    29281 ttaaattttg gctttctgtt gagaatacaa atataaatta tccagttgta caatctaaag
    29341 ataattctta ctatcttgac aaagattttt ataaaaaaga ttctatttct ggtacactgt
    29401 ttatggatta tagaaataaa tctattgatg acaaaaatat cataatatat ggacataata
    29461 tgaaaaataa aactatgttc aacaacctaa ataagtttaa agatgctgac ttctttaaaa
    29521 aaaataataa aataaaaata accttgaatg gaaaagaatt tttatatgat gttttttctg
    29581 cttatattgt agaatctgat tatgattatc taaaaacaaa ttttaacaat gaatctgatt
    29641 atcaaaatta cataaatgat attacttcta aatcattgta taaatctcct attaaggtaa
    29701 atagcaatga taaaatagtt acactttcta catgtaccta tgaatttgat gatgccagaa
    29761 tggtgattca tggtagattg atttaaaact cacagacaca gtttaaaaca ataattttaa
    29821 actgtgtcat cttttatacc tataatttgt aaattagacc actaaaagta tttaatacaa
    29881 aataacaaat acatcaaaca ataaaaaaca ataaaaaaag actatgctaa aaacatagtc
    29941 tttactggag ctggtgatag gaatcgaacc tacaacctgc tgattacaag tcagctgctc
    30001 taccgttgag ccacaccagc acacctattt tattgtaaat tagcaaaact aatttttaaa
    30061 agtta
//
LOCUS       DAYAOO010000047        29496 bp    DNA     linear   BCT 12-OCT-2024
DEFINITION  TPA_asm: Clostridioides difficile isolate ST8-SSI-h139-18
            SAMN40601845-rid21577343.denovo.047, whole genome shotgun sequence.
ACCESSION   DAYAOO010000047 DAYAOO010000000
VERSION     DAYAOO010000047.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN40601845
            Sequence Read Archive: SRR28438827
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 29496)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 29496)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-MAY-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-MAY-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002157583.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002157583.1
            Genome Coverage       :: 163x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/11/2024 16:19:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 4,038
            CDSs (total)                      :: 3,963
            Genes (coding)                    :: 3,930
            CDSs (with protein)               :: 3,930
            Genes (RNA)                       :: 75
            rRNAs                             :: 6, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 60
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 33
            CDSs (without protein)            :: 33
            Pseudo Genes (ambiguous residues) :: 0 of 33
            Pseudo Genes (frameshifted)       :: 7 of 33
            Pseudo Genes (incomplete)         :: 25 of 33
            Pseudo Genes (internal stop)      :: 11 of 33
            Pseudo Genes (multiple problems)  :: 8 of 33
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..29496
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN40601845-rid21577343.denovo.047"
                     /isolate="ST8-SSI-h139-18"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Denmark"
                     /collection_date="2018"
                     /collected_by="Statens Serum Institute"
     gene            550..705
                     /locus_tag="ACGI5H_002297"
     CDS             550..705
                     /locus_tag="ACGI5H_002297"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9697998.1"
                     /translation="MDEERKKLIDDAEKLANIGINQILKFRDSLDIENIKYINIVATN
                     LKPNIKK"
     gene            complement(724..1080)
                     /locus_tag="ACGI5H_002298"
     CDS             complement(724..1080)
                     /locus_tag="ACGI5H_002298"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009904212.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HFG9697999.1"
                     /translation="MHERIYKIRTSLKMSQREFGEKLGVSRDVISNIEYNRVTPKPVF
                     IQHLCELYNVNKEWLLTGEGEMFIEFSENEKVLKIATDIINEDDKFMKNILFTFSNLN
                     DEQKEFLINLMKNMTQ"
     gene            1243..1428
                     /locus_tag="ACGI5H_002299"
     CDS             1243..1428
                     /locus_tag="ACGI5H_002299"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9698000.1"
                     /translation="MKTQKTTSHLNNLNLDDDDRKLIQMTLLFKKLNLEQQNYISAMA
                     DGMKVSNELLEKSTMNN"
     gene            1548..2288
                     /locus_tag="ACGI5H_002300"
     CDS             1548..2288
                     /locus_tag="ACGI5H_002300"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009904215.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Bro-N domain-containing protein"
                     /protein_id="HFG9698001.1"
                     /translation="MSNNLQIFKNNDFGEIRVIELNGEPWFVGKDVAETLGYKDTSDA
                     LKRHVDDEDKGVGEIPTPGGNQNMKIINESGLYSLILSSKLSTAKKFKHWVTRDVLPS
                     IRKTGTYSTKSKDESEIKYMNAQARLKNARAREAKIYLELADKVDIKEYKQIMYSKTT
                     ELLSGETLIPLPKIDKKTYSATEVGKMLGISANKVGGLANAYNLKTDEYGINVWDKAK
                     YSDKQVPNFRYYENVIPVLEKVLKGFEN"
     gene            2345..2938
                     /locus_tag="ACGI5H_002301"
     CDS             2345..2938
                     /locus_tag="ACGI5H_002301"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429814.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9698002.1"
                     /translation="MKENNRIVSVGTESEMDLTAKELNMIDDFKEVMNGVNNEIANDY
                     GFLEIDRDILDKIALSTALNYKKMNFEYSEIDEKLFDDFTFEFMLKFFGDIEEDELIK
                     YLVYIGEESYELNDREKIFYKIVDTLDTIADIKITDQNKIEKEVGMCIGEDNYITYCI
                     DEDLIKFYIKDEEELVINKNSPLLYMLDTLFYEVHEE"
     gene            3007..3225
                     /locus_tag="ACGI5H_002302"
     CDS             3007..3225
                     /locus_tag="ACGI5H_002302"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894510.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9698003.1"
                     /translation="MKILQQFKPYKYDEEKNIEYDEKIIANQNTEVYIVYPRISDEEN
                     RRRWKEFDEVAKEVAINIAMKKAETVES"
     gene            3340..3501
                     /locus_tag="ACGI5H_002303"
     CDS             3340..3501
                     /locus_tag="ACGI5H_002303"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9698004.1"
                     /translation="MLSLDISKKNVMTLKKDGKFLADIVFKDIKTGKKISVGTLNKKS
                     AGQSNQHNK"
     gene            3546..3719
                     /locus_tag="ACGI5H_002304"
     CDS             3546..3719
                     /locus_tag="ACGI5H_002304"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9698005.1"
                     /translation="MVEVNIKIKGEASEIIDSIRAIFNSFGEDSMTEIKAEQEYKSRR
                     SRKLKTEDLSDQE"
     gene            3735..4988
                     /locus_tag="ACGI5H_002305"
     CDS             3735..4988
                     /locus_tag="ACGI5H_002305"
                     /inference="COORDINATES: protein motif:HMM:NF012403.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0140658 - ATP-dependent chromatin
                     remodeler activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="SNF2-related protein"
                     /protein_id="HFG9698006.1"
                     /translation="MQLYKHQEEALKLTEYNNKCAYYLDMGLGKTFVGSEKLINLGSN
                     TNLLICQKSKIDDWVHHFKTYYPDMGIINGTKKLSEGIEYFKIVEVPFIVVINYELAF
                     RRKELLDLKDFTLMLDESSMIQNEKAKRSKFVLSLNPKNVILLSGTPCSGKYEQLYSQ
                     IKLLGWNISKDLYWKQYIDVEYKDIGGFPMKVVTGYKNVDRLKKKLRDYGAVFMMSDE
                     VFDLPKQIDNVMKISTTREYRKFKKDSIISISDDIELVGDTTLTKMLYERQLCSQYNK
                     FKLEAFGDLINSTSDRLIVFYNFNEELDRLIELSRDRPISIVNGSIKDLSNYEEYNNS
                     ITFVQYQAGAMGLNLQKCNKIVYFSLTLSCELFMQSKKRVHRIGQENTCFYYYMICRN
                     SVEENIYKSLQSGVDYTNNLFERGE"
     gene            4992..5294
                     /locus_tag="ACGI5H_002306"
     CDS             4992..5294
                     /locus_tag="ACGI5H_002306"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003500708.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VRR-NUC domain-containing protein"
                     /protein_id="HFG9698007.1"
                     /translation="MGAEKQFENKVKKFLKEQGCWFIKYWGGSAYTKSGIPDLLVCCS
                     GKFIGIEVKGEKGKASELQKYNIKEIEKAGGIGIILYPKDFDRFKKMILEIKKEGE"
     gene            5295..6980
                     /locus_tag="ACGI5H_002307"
     CDS             5295..6980
                     /locus_tag="ACGI5H_002307"
                     /inference="COORDINATES: protein motif:HMM:NF024870.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HFG9698008.1"
                     /translation="MQFSHSRIGVFKSCPYKYKLQYIDKVKTILNADANNALILGTSL
                     HTGIEKDIDAAVKEYYFSYPSITDLHINEVMKLDYLIPKVKEILPKGFNEVQITTSDF
                     IGFIDLLAPHVYMTDTNLNTNETTIYYEDEERVFDIYDFKYSNNIDRYLESEQLHLYK
                     YFYEKQHTNHEIKDLYYVFVPKIQIRQKKTENLHQFRQRLLNELDKSEIKIVKVEYDP
                     NKVINFLVDIKRCLENKEFEKNQNKLCNWCDYQEYCEKGIDYMLLPNSERRSVEGINK
                     KTLWIYGAPFSGKTTLANDFEKPLMLNTDGNIKFVDAPYISIKDIVTVEGRMTKRQLA
                     WDVFKEAIRELEKKENDFETIIVDLLEDTYEACRLYMYDKMGITHESDDSFRAWDKVR
                     TEFLSTIKRLMNLDYKNIILISHEDTSKDITKKGGDKITAIKPNLQEKAANKIAGMVD
                     IVARVVADGDVRTLSFKTNEVIFGGGRLKVKSNEIPLDYNELMKVYDDISIEKKDVKK
                     SSKTKKSNAEEEVEMTPTVEEISEKTEKEQTEEEVIEQEEAIKPVKKTRKKRS"
     gene            7044..7487
                     /locus_tag="ACGI5H_002308"
     CDS             7044..7487
                     /locus_tag="ACGI5H_002308"
                     /inference="COORDINATES: protein motif:HMM:NF016896.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF669 domain-containing protein"
                     /protein_id="HFG9698009.1"
                     /translation="MDFSKFDKAIDVKGLKEDIKEASENSGKFKDVPHGTYEVEINKM
                     ELSESKKGDPMFVCWFKILEGEYKDSLIFMNQVVKQGFQIHIVNEFLRSLETDIEVEF
                     ESYSQYAQLIMDIAEEIDGELEFAIEYGEKKGFNTFTIKDIFEVA"
     gene            7572..7700
                     /locus_tag="ACGI5H_002309"
     CDS             7572..7700
                     /locus_tag="ACGI5H_002309"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429830.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9698010.1"
                     /translation="MELISPGKIVRCVWCGKRFYKLDNSKVIYCSRKCAAKARGVF"
     gene            7701..9434
                     /locus_tag="ACGI5H_002310"
     CDS             7701..9434
                     /locus_tag="ACGI5H_002310"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9698011.1"
                     /translation="MIFYDFEVFSYDWLVVFIDVLNKKEEVIVNDIDKLNSFYIEHRE
                     DIFIGYNSRHYDQYIFKGLLCGFNAKEINDYIIVKGQPGWKFSNLLRNIQINNYDVMT
                     SFHGLKQLEGFQGHSIKESNVSFNIDRPLTNDEIEETIKYCRYDVEQTIDVFIERKSE
                     FEAHMGLIKAFKLPVAYIGKTQTQLTAIILEATKKEHDDEFDLQIPDTLKIEKYKEVL
                     SWYKNPLNHDYSKNLKINISNVPHVFAWGGVHGAITKYYGEGYFLHVDVNSFYPSLMI
                     RYNYHSRNIKNPQKYVEIYDKNLQLKKEKSPLRPAYKLAVNKTYGGMKDKNNNLYDPR
                     QANNVCVSGQLLLLDLIEKLEGHCKLIQSNTDGLIVKLNTIDDYELIDDICYEWEQRT
                     GMGLGFDVYTKIFQKDVNNYLVITEDGEVEAKGLYIKDLGNLDYDLPIINKALKNYMV
                     NNTPIEETINKCNDLIEFQKIVKISSKYSHGLYSPTIEGKTKKVFIGGKILNDKCFRV
                     FASKNKNDGGIYKVKNKEKNPEKFANTPDKCFIENGSVIGKKVPRKLDKTWYIDLANE
                     RLKQFGVLLSN"
     gene            9446..11326
                     /locus_tag="ACGI5H_002311"
     CDS             9446..11326
                     /locus_tag="ACGI5H_002311"
                     /inference="COORDINATES: protein motif:HMM:TIGR01613.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003896 - DNA primase activity [Evidence
                     IEA];
                     GO_process: GO:0006260 - DNA replication [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phage/plasmid primase, P4 family"
                     /protein_id="HFG9698012.1"
                     /translation="MSFDIFKGYIITNNKKAAEKFKNVKKLKTYEQIKNLPEFAGVLA
                     EETVLVDIDDFESSEILYKIVQDLKLKCRVYKTTRGKHFLFKNTSLEKNRTKCRLAIG
                     LNSDIKLGCKNSYSILKFNNIEREILYDSKEIQEIPTYLTPIKNGLDFLSLGEGDGRN
                     QALYNYILTLQSNDFTIEEIRETIRVINKYVLKTPLQDNELEVILRDESFQKKIFFNS
                     KGSFLFDEFAKYIKNNNHVIKINEQLHLYKDGIYVDGQARIEAEMINNISNLNKAKRS
                     EVLSYLNLLISENTSMSEANLIAFKNGIYNIVDDSFIEFSPEFIITNKVNWNYNPGAY
                     SKLVDKTMNKLSCGDFEIRMLLEEVVGYCFYRRNELRKAFILTGDKANGKSTYLDMIK
                     TLLGDENTSALDLKELSDRFKTAELFGKLANIGDDIGDEFIANPAIFKKLVSGDRVNV
                     ERKGQNPFDFNNYSKFLFSANNIPRIKDKTGAVLDRLIIIPFNASFSVNDKDFDPYIK
                     YKLREQEAIEYLINLGLEGLKRVLKNRKFTVPDKVKKEILEYEEVNNPILGFFKEVDK
                     IENESTKEIYMKYQEYCILNGLQPISNVEFSRQVVKKFGYEIKDKKINGKKYRVFING
                     SR"
     gene            11333..11470
                     /locus_tag="ACGI5H_002312"
     CDS             11333..11470
                     /locus_tag="ACGI5H_002312"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9698013.1"
                     /translation="MVQDIGSRCNAVISMGFKMVQDVFDLYIYLSKKSSQKVDDFAPF
                     I"
     gene            11704..12111
                     /locus_tag="ACGI5H_002313"
     CDS             11704..12111
                     /locus_tag="ACGI5H_002313"
                     /inference="COORDINATES: protein motif:HMM:TIGR01636.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006352 - DNA-templated transcription
                     initiation [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sigma factor-like helix-turn-helix DNA-binding
                     protein"
                     /protein_id="HFG9698014.1"
                     /translation="MTDYEKLEELLNSYSNLDIEIREIELKVRGSSLRGIELNGMPKG
                     NNVSSPIENELIYVERLENEKIYLQIKKESVNNMLNLLDDFERNLIELRYFKKLQYKQ
                     ISYELNISELYVGKKRKKALDKILPFAKKYNLI"
     gene            12308..12763
                     /locus_tag="ACGI5H_002314"
     CDS             12308..12763
                     /locus_tag="ACGI5H_002314"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002844934.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HFG9698015.1"
                     /translation="MAKYEYWITEEGLIKIEGWARDGLTDEQIAFNIGINVKTLYDWK
                     KKYSNICNALKKGKEVIDRQVENALLKRALGYEYDEITYEEGQETKRVTKQVVPDTTA
                     QIFWLKNRKPAEWRDKQIVESTNEITINNPFKELSTEELKRLAKLDDDG"
     gene            12750..14162
                     /gene="terL"
                     /locus_tag="ACGI5H_002315"
     CDS             12750..14162
                     /gene="terL"
                     /locus_tag="ACGI5H_002315"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006440365.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage terminase large subunit"
                     /protein_id="HFG9698016.1"
                     /translation="MTMDKKLIQLEAKKELARREFFYFCNLLAPKFYKEDRKYLVETC
                     NKLQDFYYSDDEVLIINMPPRHGKSRSASLFVEWILGKNKNEKIMTGSYNETLSTMFS
                     KNVRNAIQEEKADIDTIIYSDIFPNTKIKHGDGAMNLWSLEGGYNNYLATSPSGTATG
                     FGCSLMIVDDLVKNAEEAYNENVLEKHWDWFTNTMLSRLEEKGKIIIIMTRWSSKDLA
                     GRVLEHYKEEGKKVRHINMKALQEDGNMLCEEVLSLKSYKSKVRAMGEDIASANYQQE
                     PIDLKGCLYTKFKTYEKLPVDGEGNLLFTSIKAYVDTADEGADYLCSIVYGVYNKEAY
                     ILDVLYTKESMEITEYKTAKMFYNNEVNKADIESNSGGRAFARNVQRILKEKFKSNKT
                     IIKWFHQSKNKNARILSNSSWVMEHIYFPINWRDKWIEFYKAMVSYQREGKNKHDDAP
                     DALTGVAEKALKGQGLSVFK"
     gene            14191..15546
                     /locus_tag="ACGI5H_002316"
     CDS             14191..15546
                     /locus_tag="ACGI5H_002316"
                     /inference="COORDINATES: protein motif:HMM:NF016988.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0046798 - viral portal complex [Evidence
                     IEA];
                     GO_function: GO:0005198 - structural molecule activity
                     [Evidence IEA];
                     GO_process: GO:0051027 - DNA transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phage portal protein"
                     /protein_id="HFG9698017.1"
                     /translation="MELEKIRAIISADIARRQEILQAKSYYYNENDILKKGVVVQNRD
                     ENPLRNADNRISHNFHEILVDEKASYMFTYPVLFDIDNDKELNEKVTDVLGNEFTRKA
                     KNLAIEASNCGTAWLHYWIDEEYSGEQVTNQTFKYGVVNTEEIIPIYRNGIERELEAV
                     IRYYVQLEDVKGQIQKQAYTYVEFWTDKILDKYKFFGVTCCGSQIEHITVQHRFNSVP
                     FIEFANNIKKQSDLSKYKSVLDLYDKIMSGFANDLEDIQQIIYILENYGGEDTAQFLN
                     ELKRYKAIKTETDSEGDSGGLKTMQIEIPVEARKVILEILKKQIYESGQGLQQDTESF
                     GNASGVALKFFYRKLELKSGLLETEFRTSFDKLIKAILYFLGVTDYKKIQQTYTRNMM
                     SNDLEDADIATKSVGIIPTKIILRHHPWVDDPEEAALLLREEKKIQASKVSDDYNNFT
                     E"
     gene            15559..16977
                     /locus_tag="ACGI5H_002317"
     CDS             15559..16977
                     /locus_tag="ACGI5H_002317"
                     /inference="COORDINATES: protein motif:HMM:NF016148.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polymorphic toxin type 50 domain-containing
                     protein"
                     /protein_id="HFG9698018.1"
                     /translation="MNNNIEYWKEREKQRLNSRLKEEKEVLKELDKQYKIAMKNIEKE
                     IANLFYKYAEQNKLTYAETQKYLTNNEFNTWRMDIKQYIKLIEQTSDERLLLELNTLA
                     MKSRINRLEELFYQISKEINNTFDIQNNRVEKLLEESVKDSYYKSIYETQKHVGVGVS
                     FTKLDREALKDIITYPWSGKNFSQRIWKNRDLLSEVIKEEITQMVIRGESLKKISNRV
                     SEKMDSSYENAIRLVQTEHSHFMSEADKKAYESQKVDKYQFLATLQDNTCKRCRSVDM
                     KVYLVKEAKEGENYPPLHPRCRCTTIPYFEDEKGGTRTARLLKGKTYEVPFNLSYNEW
                     YKNHVEVAINREKENKNNVIINNIKKDIKDGKYNLNIHNGKQGKHFKDHNNYTEGRSY
                     LTVSKEEVQELINKYAGTGILELDRNGKFKNKELITCEKNIGVNISNLTGEETETNKF
                     YIHYSKNGTHIVPTMKGVEKDE"
     gene            16970..17167
                     /locus_tag="ACGI5H_002318"
     CDS             16970..17167
                     /locus_tag="ACGI5H_002318"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9698019.1"
                     /translation="MSKNLINYMSEKVKIIDIDNKEWIGYVKTYTPAIDSDNEINEIG
                     LKQEDCLISFQEDEIKSIEII"
     gene            17235..18077
                     /locus_tag="ACGI5H_002319"
     CDS             17235..18077
                     /locus_tag="ACGI5H_002319"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9698020.1"
                     /translation="MAKFKKKPVEVEAFRLGYDIEPEWFFENSRVCNFIQEKCIDGNV
                     SCDLKTLEGTMRANKGDYIIQGVKGEIYPCKADIFEMTYEKVEYTATIENLTNYAENI
                     EKGHRCADEDNNKENKLELSAKLELDTKDFEENIKNATKEIEIFNKAVGTLEQKINGI
                     FGREKVNEVKINIPTISKSESVEEVNGKLLKELKSQKLIVSEKDKKFKKYDICFKNGE
                     CISGVIKEHVADKLTAYFCDSQSDIDCLRAIEDEEKLVMFNTANVQTITISDYIENEE
                     IDYI"
     gene            18113..18304
                     /locus_tag="ACGI5H_002320"
     CDS             18113..18304
                     /locus_tag="ACGI5H_002320"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9698021.1"
                     /translation="MSWLILQIVSIVVNVILIISLVSDIVLKIYLKSLKKEYEVAINK
                     ASNELLKKLNDELRKRKSL"
     gene            18422..19018
                     /locus_tag="ACGI5H_002321"
     CDS             18422..19018
                     /locus_tag="ACGI5H_002321"
                     /inference="COORDINATES: protein motif:HMM:NF018515.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0019069 - viral capsid assembly [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phage scaffolding protein"
                     /protein_id="HFG9698022.1"
                     /translation="MEWLRKILESIKIEENKIDVEEILKSVNTEFPKYAVPKETFNKT
                     NEQLKEANKAIESFNSKMTQEDLEKIKTEHQAQIKKIEENHKIEVEKMQNESLKTRKL
                     SAVEKALLTNKAKHTDLLTNKFDLEKITIGEDGKIVGIEEQLKELQESYKDLFESSTT
                     ETTTQTNTPFYKYVPGGSGETNETANMETVVNGILGVK"
     gene            19042..19980
                     /locus_tag="ACGI5H_002322"
     CDS             19042..19980
                     /locus_tag="ACGI5H_002322"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015981494.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9698023.1"
                     /translation="MANILAYGQVLQQGLDKQATQELLTGWMDSNAKQIKYEGGKEVK
                     IGKLSTDGLGDYSRGSANAYVGGDVKFEYETKIMTQDRGRKFTLDAMDVDETNFLVTA
                     TTVMGEFQRLKVIPEIDAYRLSRLATIAISIEGDINVEYGYTVNSSTIINKIKTGIKI
                     IRENGYNGPLVCHLTYDSMFAIEEKVLEKLTAVTFAQGGIQTQVPSIDGCPLIKTPQN
                     RMYSSILLNDGTTSGQTAGGYLKGTKALDTNFIIAPVDVPLAITKQDKMRIFDPETNQ
                     TANAWSMDYRRYHDLWVTDNKANSVYANFKDAKPTA"
     gene            19993..20214
                     /locus_tag="ACGI5H_002323"
     CDS             19993..20214
                     /locus_tag="ACGI5H_002323"
                     /inference="COORDINATES: protein motif:HMM:NF019139.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0006353 - DNA-templated transcription
                     termination [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Rho termination factor N-terminal
                     domain-containing protein"
                     /protein_id="HFG9698024.1"
                     /translation="MFILIKENIERSVEDSFLKDKLIQDGFKLLEDKKNIDIENSTLE
                     ELKNLAKENGIEGYSKLKKDELIEKLNSI"
     gene            20243..20584
                     /locus_tag="ACGI5H_002324"
     CDS             20243..20584
                     /locus_tag="ACGI5H_002324"
                     /inference="COORDINATES: protein motif:HMM:NF016990.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage head-tail connector protein"
                     /protein_id="HFG9698025.1"
                     /translation="MLDNIKLILNLKDDTHDSLIELYIKKYTTLVLAYCNIETLNSTL
                     EGIVEDKVIVKLKETVLVSSADNGISSISRGGYSVNYNVATAKTTDELMEIKLSQKDK
                     NILNNFRKVRW"
     gene            20586..20936
                     /locus_tag="ACGI5H_002325"
     CDS             20586..20936
                     /locus_tag="ACGI5H_002325"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015981496.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9698026.1"
                     /translation="MTEADILALTYFCKMTIRRCVSSKNEETGVTDFNESLVIAEDVP
                     CGLSGNIPNVIDTDITSSISVFELYCRPEVDLRVGDILDITLENGAVETFIVSKPFPY
                     SSHLQTNLTLKERY"
     gene            20937..21347
                     /locus_tag="ACGI5H_002326"
     CDS             20937..21347
                     /locus_tag="ACGI5H_002326"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015981497.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HK97 gp10 family phage protein"
                     /protein_id="HFG9698027.1"
                     /translation="MIEFNSLDTLIRDLEREEREMSKNLRRAKNNIGNKLLRKVKPKT
                     PVAKVDGGTARKSWKYKELNLFEGVVSNNVEYIYHLEYGHRTRQGTGTSENYRPKPNG
                     ISFVPGVFMLARSVDEMSSIIDDELNQIIIDFWN"
     gene            21358..21810
                     /locus_tag="ACGI5H_002327"
     CDS             21358..21810
                     /locus_tag="ACGI5H_002327"
                     /inference="COORDINATES: protein motif:HMM:NF044614.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF6838 family protein"
                     /protein_id="HFG9698028.1"
                     /translation="MLSYKDILYSFTKELGNNFNEDIFVEGYNIQDNKKSCFFVQILP
                     EVAQTATKKTDIKSFLVDIKYLPDWKKKKTDLFDILNKLENIFTRNIKVKDRYLTFSK
                     KNGSIEKDEIGNYVQFLISINYHEQIYFEEEKHELMEELNMRFKGRSD"
     gene            21811..22881
                     /locus_tag="ACGI5H_002328"
     CDS             21811..22881
                     /locus_tag="ACGI5H_002328"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861188.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail sheath subtilisin-like
                     domain-containing protein"
                     /protein_id="HFG9698029.1"
                     /translation="MAGLVNINIEFKELATSFIQRSQTGIVAIILKDTTKMYKELTSE
                     DDIPISLSADNKKYIKYGFVGATDNEKILRPSKVIISTFTEDGKVEDILEELESVEFN
                     YLCMPEAIEAEKTKIVNWIKKIREEESTEAKAVLANIKADNEAVINFTENVTVGGEEI
                     TAEKYTPRIASLIASTPSTQSITYAPLNEVESITKIDKASADAKVQSGELILRRLSGA
                     IRIARGVNSLTTLTQEKGEIFQKIKLVDTKDLISKDIKDIYVKSYIGKVPNVYDNKCL
                     FIIAIQAYLAELAKQELIDSNFSVDIDIEKQKEYLEGKKVDTSKMKEDEIKEANTDSS
                     GFYLIKLKLVDAMEDINISVQM"
     gene            22897..23328
                     /locus_tag="ACGI5H_002329"
     CDS             22897..23328
                     /locus_tag="ACGI5H_002329"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015981500.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail tube protein"
                     /protein_id="HFG9698030.1"
                     /translation="MATSYEPRNVINGTYGEVWINNQQIAECKAMKAEIKFDKAEIVR
                     PRKIIKGQKIISASAEGSLTLYHVDSKILDYVTQIIKEGREPKFTITSKLSDPDSFGT
                     ERIAITGVSFDGLTIIDWENGKEGEKEVSFTFEDYNPIQTI"
     gene            23358..23825
                     /locus_tag="ACGI5H_002330"
     CDS             23358..23825
                     /locus_tag="ACGI5H_002330"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015981501.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9698031.1"
                     /translation="MSENKLEKEMVDKKEMTEVKNVVDLLLSLDADKVKMPSITHTIF
                     CKKLGIDVNFECKAIEPEFFDELQTSGLKIEKGSLKDLDNFKMKSNVILASCNLFKDD
                     KLLKHFQSPTPKELLRRMLLAGEINELYDKICELNGYRDDNKKDKEIEEKIKN"
     gene            23852..23998
                     /locus_tag="ACGI5H_002331"
     CDS             23852..23998
                     /locus_tag="ACGI5H_002331"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009899645.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9698032.1"
                     /translation="MYLMFRYHNMLPSDFFKLKYGEKHVIRAFMYQEIDERIEEIKSF
                     GKGL"
     gene            24002..26836
                     /locus_tag="ACGI5H_002332"
     CDS             24002..26836
                     /locus_tag="ACGI5H_002332"
                     /inference="COORDINATES: protein motif:HMM:TIGR01760.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005198 - structural molecule activity
                     [Evidence IEA];
                     GO_process: GO:0016032 - viral process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail tape measure protein"
                     /protein_id="HFG9698033.1"
                     /translation="MSAGSRALEAVIRMRDEASRTLRQVRDATRALQNQTNTTSQAQE
                     RLQEQFRKVSNAAKIAGVGIATGIGAGLVSASKAGAEFETAMTKTSTMFGDTKVDTEN
                     LNNKVLELSKNTGIAASSIGESLYNALSSGIPVTKDMGSAMDFMTKNAKLSKAGFTDI
                     DTALTATAKVLNAYKMDVSETDRVHKVMMQTQNKGITTVGELGATLAQVTPTASAMSF
                     SFEQVGASLANMTAQGTPTAQATTQLNSLLAELGKTGTVANKSLLDATKGTKYAGKSF
                     KELMQAGVPLNEILNLMDGSAKKNKKSLIDMFGSIEAGKAALALSGQNSEQYTNNLKA
                     MSTQADVVSSAYAKMSNTLESKVGILKESFKNLGIEIYSKLKEPLKNAAETGIQCLSD
                     LDKQFSSGSLKAGISQIAQSFGDLTSAIIKIATKALPTMVKSLSWVLKNGPTIASIFV
                     SIKTASIMTSAVKSIVALKKAWVAAKLAVRVYMVGMAEAGTVLSGFQVLVGVLTREMT
                     IAQGVTQVWSATLATLGGPVGVAIIAIVALVAGLVVLWNTNKGFRDFVINTWNNIKET
                     ATKVWGGICNFFTQTIPQAWNDLCTSFSNAGQWFGEMWNNIKQAFINGWNAIVAFFTQ
                     TIPMWINSIGVWFGQLPAKIGYGLGFALGKIISWGISVWTYLVTNVPIWINNIGTFFA
                     QLPNKIWTWLVSTVQKIGQWGMAMIAYAQIYARMIINNIVVFFQTLPSRVWTWLTNTV
                     QKVVSWGSQMASKGREGAKKLITTVVDTLKSLPKKVMDIGKNIVKGLWEGITGAGDWL
                     KGKVGDFANGVINGFKDGFGVHSPSWKLRDLVGKFLPPGIWNGIKMTLPKLETNITGM
                     VDSLVKRMYNPKEVEESNYTSKYKEAIAQRTEQNTINKTDSKTTNNKESNNITININW
                     GGVTVKEEADMTKLTKMLVNEIKLNLAGGV"
     gene            26911..27711
                     /locus_tag="ACGI5H_002333"
     CDS             26911..27711
                     /locus_tag="ACGI5H_002333"
                     /inference="COORDINATES: protein motif:HMM:NF025826.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SHOCT domain-containing protein"
                     /protein_id="HFG9698034.1"
                     /translation="MALFSSKENCVICGEKTKNLKIKDGYVCKKCLQRCTGIEYVLNP
                     AFGSAFLNKKNKEVTKEDILGLLEKRGNNLDELDNFNTTKQVSVYLEIDEVQRKCLIP
                     DGSIGKKINPKIFSFDEIVEYELVEDEESIIKGGLGKAIAGGVLFGGVGAVVGGVTGK
                     KKTKTVVNSLKIKITLNNLNYPNVYINLITTQTKTDSFIYKNAYDSAQQILSMLSIIQ
                     NGNNENSIEKNTESNSSLEQIKTLKELLDMGAITEEEFNAKKKELLNL"
     gene            27766..27957
                     /locus_tag="ACGI5H_002334"
     CDS             27766..27957
                     /locus_tag="ACGI5H_002334"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9698035.1"
                     /translation="MNKGIKFIGSLKRLNFLIQAKENLIKDIHEYSNNEEEIARYENL
                     DKAFEKTIIDEAKFLISLE"
     gene            27981..28610
                     /locus_tag="ACGI5H_002335"
     CDS             27981..28610
                     /locus_tag="ACGI5H_002335"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425688.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysM peptidoglycan-binding domain-containing
                     protein"
                     /protein_id="HFG9698036.1"
                     /translation="MWIRQANDTFRFPVFPSSFEINSKAIVNTSNVLKTGEIAVFGGV
                     GLRTTEISSFFPKNEASYCDYTGFPSPYDCVNKIQRWMNEGFILRFTITETNINFECI
                     ITDFQYEEKDCTGDVYFTLSLKEYKRIQIPKVSTNTDLSSSKDVPLTKGFEVKNKQRT
                     HKVGKGDSLWSLAKKYYGNGDLWKKIYDANKKLIKNPDIIKDGWVLVIP"
     gene            28625..28900
                     /locus_tag="ACGI5H_002336"
     CDS             28625..28900
                     /locus_tag="ACGI5H_002336"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015981507.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9698037.1"
                     /translation="MDKLRIISESNSLTKEDLTEKDLYCIGKFIQIGAIKSFMHNEKD
                     LDFPCTDCKYSDKCFGDNRESDFWDTFLKLSKLTDLKLSPFKGFNIN"
     gene            29159..>29496
                     /locus_tag="ACGI5H_002337"
     CDS             29159..>29496
                     /locus_tag="ACGI5H_002337"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419653.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall hydrolase"
                     /protein_id="HFG9698038.1"
                     /translation="MIINRSKDSSNNSISFTSKDMGFLLTQSEVSYNFKDKLVEDIAK
                     QVFNDNKLAIGNIPKTNVKYTKMFIGVTGYDTIMSAYTEASKTTKKKYMIESNLDKFN
                     IIEKGTVTLNV"
BASE COUNT        12407 a         2965 c         5428 g         8696 t
ORIGIN      
        1 taaattgttt gtgaaatgaa aaaatgttaa aaaaaagatt acttgacaac cataaaaata
       61 atttatttgc aatcaaaaac cactaaaaac actgaaaatt caaatttttt tacaaaaata
      121 tgtgaaaata ttgtattttt attgatgaga tattattatt aatctatcga agtagaaaat
      181 taatttatag aaaatattta catataaatt aaaaaaattg acatatgtag gaaataattt
      241 ataagttaag gtcatggaat ttttatacct attcttgcga acgtaagttc ttgaaatatt
      301 aatatttctt aattttagat gaaaatagga aatataaaac gtttaaagaa gacaagagaa
      361 taaagaataa atatataggg ggatgcttta agtgaaaata taaataatgt actaaattta
      421 tacaaataag gaaataatat atagtgtatt taaaaataaa aaggctggtg gtgttaattt
      481 gaagtatttt taagtgtata tttataatat aaggggaatt tttatattta tgaatggagg
      541 aatatagtaa tggatgaaga aagaaaaaaa ttaattgatg atgcagaaaa gctagcaaac
      601 ataggaataa atcaaatttt aaagtttaga gattcattgg atatagaaaa tataaaatac
      661 ataaatatag ttgcaacaaa tttaaagcca aacataaaaa aatagccacc cttttgggtg
      721 gttttattgt gtcatatttt tcattaagtt tataagaaat tctttttgct catcatttag
      781 attactaaaa gtaaataata tatttttcat aaatttatca tcttcattta taatatctgt
      841 tgctattttt agtacctttt cattttcaga aaactctata aacatttcac cttcgccagt
      901 taagagccat tctttattaa cattatatag ctcacataag tgttgtataa atacaggctt
      961 aggtgtaacc ctgttatatt caatattact tatgacatct ctgcttacac caagtttttc
     1021 accgaattca cgttgagaca tttttaagga tgttcttatt ttatatatac gttcatgcat
     1081 gattttcctc ctaataatta cgttattaat tagatagtat aacacaaaaa agaattagtc
     1141 aacataaatg ttgtggtaaa aacacaaaaa tatttaaaaa caagtgttga ctacacaaaa
     1201 ataagatgat atactgtgtt tataacacaa ggaggtgcta aaatgaaaac acaaaaaact
     1261 acttctcatt taaataattt aaatttagat gatgatgata gaaagcttat tcaaatgact
     1321 cttttgttta aaaaattaaa tttagaacaa caaaattata tctctgcaat ggctgatgga
     1381 atgaaagtgt caaatgagct tttagaaaaa tcaactatga ataactgata caaaggtaca
     1441 aagctggaat aagatttcga ccacaagtgg gcgaaagatg actggagtag atttattagg
     1501 tgtcattcaa accgacacca aaataaaaag ctagggagga agaaattatg agtaataatc
     1561 tacaaatatt taaaaataat gattttggag aaataagggt tatagaatta aatggagagc
     1621 cttggtttgt tggtaaagat gtagcagaga cattaggata taaagataca tctgatgctt
     1681 taaaaagaca tgttgatgat gaagataaag gggtaggtga aataccgact cctgggggta
     1741 atcaaaatat gaaaataatt aatgaaagtg gtctttattc tttaatatta agttctaagt
     1801 tatcaactgc taaaaaattt aaacattggg taacgagaga tgtactacca agtataagaa
     1861 aaacaggtac atacagcact aaatctaaag atgaatcaga aataaaatac atgaatgctc
     1921 aagcaagatt aaaaaatgca agagcaagag aagcaaagat atatctggaa ttagctgaca
     1981 aagtagatat aaaagaatat aaacagatta tgtattcaaa aactactgaa ttactttctg
     2041 gagaaacatt aataccacta cctaagatag ataaaaaaac ttattcagct acagaggtag
     2101 gtaagatgtt aggaatttca gctaataaag ttggaggatt agcaaacgct tataatctaa
     2161 aaacagatga gtatggaatt aatgtatggg ataaagctaa atattcagat aaacaagtac
     2221 ctaattttag atattatgaa aatgtaatac cagttttaga aaaagtacta aagggttttg
     2281 aaaactaaat tcagaagttg ctaaatataa ctttaaaaac ttaaatttaa ggaggaataa
     2341 gaaaatgaaa gaaaataaca gaatagtaag tgttggaact gaaagtgaga tggatttaac
     2401 agctaaagaa ttgaatatga tagatgattt taaggaagtt atgaatggtg ttaacaatga
     2461 aatagctaat gattatggtt ttttagaaat agatagagat attttagaca aaattgcatt
     2521 aagtacagct ttgaactata aaaaaatgaa ttttgagtat tcagaaatag atgaaaaact
     2581 atttgatgat tttacttttg agtttatgtt aaagttcttt ggtgatatag aagaggatga
     2641 attaatcaaa tatcttgttt atataggtga ggaaagttat gaattgaatg atagagaaaa
     2701 gatattttat aaaatagtag atactcttga tacaatagca gacataaaaa taacagacca
     2761 aaataagata gaaaaagaag taggtatgtg cattggtgaa gataattata taacttattg
     2821 tatagatgaa gacttaataa aattttacat taaagatgaa gaagaactag ttataaataa
     2881 aaatagccct ctgctatata tgttagacac actattttat gaagtacatg aagagtaaaa
     2941 attgcaataa ttaaataagt ataagacaag tttatgagct catattttat aacaaggggt
     3001 gatgttatga aaatactaca acaatttaaa ccatacaaat atgatgaaga gaaaaacata
     3061 gaatatgatg aaaaaattat agctaatcaa aacacagaag tttatatagt atatccacgt
     3121 atatctgatg aagagaatag gagaagatgg aaagagtttg atgaagtagc caaagaagta
     3181 gctattaata tagcaatgaa gaaagctgag acagtagaaa gttaagaaag tagagaagtt
     3241 gctaatactt agcactttct caaagaagaa aattggacaa ctatttttaa acaactagga
     3301 ataaataagc gatagtatgt ttgaaagaag gtgatgaaat tgcttagtct tgatattagt
     3361 aagaaaaatg tgatgactct taaaaaagat ggtaagtttt tagcagatat agtatttaag
     3421 gacattaaaa ctggtaaaaa aatatcagtt ggaacattaa ataaaaaaag tgctggtcaa
     3481 agtaaccaac acaataaata aaaaaaaaca tatgaaaatt ataacataaa aaggagagat
     3541 ttaaaatggt tgaagttaat ataaaaatta aaggcgaagc aagtgaaata attgactcaa
     3601 ttagagctat atttaatagc tttggtgaag attcaatgac agagataaaa gcagagcaag
     3661 aatataaaag tagacgtagt agaaagttaa aaacagaaga tttatcagac caggaataaa
     3721 gaaggtgata taagttgcaa ctatataagc atcaagagga agctttaaag ctaacagaat
     3781 ataataataa atgtgcatac taccttgaca tggggcttgg taagacattt gtaggaagtg
     3841 agaaattaat aaatctagga agtaatacaa atttattaat ctgtcagaaa tcaaaaattg
     3901 acgattgggt acatcacttt aaaacatatt atccagatat ggggataatc aatggtacaa
     3961 agaaacttag tgaaggcata gagtatttta agattgttga agttccattt atagtagtaa
     4021 ttaattatga attagctttt agaagaaaag agttattaga tttaaaagat tttactttaa
     4081 tgttagatga atcatcaatg attcaaaatg aaaaagctaa aagaagtaag tttgtactaa
     4141 gtttaaaccc taagaatgtg atactacttt ctggtactcc atgtagtggt aaatatgagc
     4201 aactatattc tcaaattaaa ctactagggt ggaatatatc aaaagattta tattggaagc
     4261 aatatattga tgttgagtac aaagatattg gtggttttcc aatgaaggtt gtaacaggtt
     4321 ataagaatgt tgacagatta aaaaagaagt taagagatta tggagcagta tttatgatgt
     4381 cagatgaagt atttgactta ccaaaacaga tagataatgt aatgaaaatt agtactacaa
     4441 gagagtatag gaagtttaaa aaagattcaa ttataagtat ttcagatgat attgaacttg
     4501 tgggagatac tacactaact aaaatgttat atgaaagaca attatgtagt caatacaata
     4561 aatttaaatt agaagctttt ggagacttaa taaactcaac aagtgacaga ttaatagtat
     4621 tttacaattt taacgaagag ttagacagat taatagaatt atcaagagat agaccaatat
     4681 caatagtaaa tggttctata aaagatttaa gcaattatga ggaatataat aactcaatta
     4741 catttgtaca atatcaagca ggagctatgg gtttaaatct tcaaaagtgt aataagattg
     4801 tatactttag tcttacttta tcttgtgaat tgtttatgca aagtaaaaag agagttcata
     4861 gaataggtca agaaaacaca tgtttttatt attatatgat ttgtaggaat agtgttgaag
     4921 aaaatatata taaaagctta caaagtggtg ttgactatac aaataatttg tttgagagag
     4981 gagagtaata cttgggtgca gaaaaacaat ttgaaaataa agttaaaaag tttttaaaag
     5041 aacaaggttg ttggtttatt aaatattggg gaggttcagc atatacaaaa agtggtatac
     5101 cagatttatt agtttgttgt agtggtaaat ttataggtat tgaagtcaag ggggaaaaag
     5161 gaaaagcaag cgaactacaa aagtataata ttaaagaaat tgaaaaggca ggtggaatag
     5221 gaattattct ataccctaaa gactttgata gatttaaaaa gatgatttta gaaataaaga
     5281 aagaaggtga gtaaatgcag ttctcacata gtaggatagg agtatttaag agttgcccat
     5341 ataagtataa gctacagtat attgacaagg tgaaaacaat attaaatgca gatgctaaca
     5401 atgctctaat attgggaaca tcacttcata caggtattga aaaagatatt gatgcagcag
     5461 taaaagaata ttattttagt tatccaagta taacagattt acacattaat gaagtgatga
     5521 agttagatta tttaatacca aaagtaaaag aaattttacc aaaagggttt aatgaggttc
     5581 aaataacaac tagtgatttt atagggttta tagatttgtt agcaccacat gtatacatga
     5641 ctgatacaaa cttaaataca aatgaaacaa ccatatatta tgaagatgaa gaaagagtat
     5701 ttgatattta tgactttaaa tattcaaaca acatagatag atatctagaa agtgagcaac
     5761 ttcatctata taagtatttt tatgaaaagc aacatacaaa tcatgagata aaagatttgt
     5821 actatgtatt tgtacctaaa attcagatta gacagaagaa aacagaaaac ttacatcaat
     5881 ttagacaaag attacttaat gagcttgata aatctgaaat aaaaatagtg aaggttgagt
     5941 atgacccaaa taaagttatt aatttccttg tagatataaa aagatgtctt gaaaacaagg
     6001 aatttgaaaa aaatcaaaat aaattatgta actggtgtga ctaccaagaa tactgtgaaa
     6061 aggggattga ttatatgtta ttaccaaata gtgaaagaag aagtgtggaa ggaattaata
     6121 aaaaaacttt atggatttat ggagcaccat ttagtggcaa aaccacatta gcaaatgatt
     6181 ttgaaaagcc tttaatgctt aatacagatg gaaatataaa gtttgttgat gctccatata
     6241 tttctataaa agatattgta acagttgaag ggagaatgac aaagagacaa cttgcatggg
     6301 atgtatttaa agaagctata agagaattag agaaaaaaga aaatgatttt gaaacaataa
     6361 ttgttgactt gttagaagat acatacgaag cttgtcgcct ttacatgtat gacaagatgg
     6421 gaataactca tgagtcagat gatagtttta gagcatggga taaggttaga acggagtttt
     6481 taagcactat aaaacgactt atgaaccttg actataaaaa cataatatta atatcacatg
     6541 aggatacatc aaaagatatt accaaaaaag gtggtgacaa gataacagca atcaaaccta
     6601 atttacaaga aaaagcagca aataaaatag caggtatggt tgatatagtt gcaagagtag
     6661 tagctgatgg agacgttaga acattatcat ttaagactaa tgaagtgata tttggagggg
     6721 gtagattaaa agtaaaatct aatgaaattc cacttgatta taatgaatta atgaaagtat
     6781 atgatgatat tagtatagag aaaaaagacg ttaagaagtc aagtaagact aaaaaatcta
     6841 atgctgagga agaagtagaa atgactccta cagtagaaga aataagtgag aaaactgaaa
     6901 aagaacaaac agaggaagaa gtaattgaac aagaagaagc aattaaacca gtcaagaaaa
     6961 ctagaaaaaa gagaagttag tttaagtgat tatataagaa agattattaa ttaaaaattt
     7021 aaaagaaaag gatggtatgt gatatggatt ttagtaaatt tgataaagca atagatgtaa
     7081 aaggattgaa agaagatata aaagaagcat ctgaaaatag tggtaaattt aaggatgtgc
     7141 cacatggcac ttatgaagta gaaataaata aaatggagtt aagcgagtct aaaaaaggtg
     7201 acccaatgtt tgtatgttgg tttaaaatac tagaaggaga gtataaagat tcattaatat
     7261 tcatgaatca agtagttaag caaggttttc aaattcatat agtaaatgaa tttttaagaa
     7321 gtttagaaac tgatattgaa gttgaatttg aatcatacag ccaatatgca caactcataa
     7381 tggatatagc tgaggaaata gatggagaac ttgaatttgc tattgaatat ggtgagaaga
     7441 aaggttttaa tacctttaca ataaaagaca tatttgaagt agcttagaaa ttttattaca
     7501 gctaggtgta tacatgcatc tagctgtaat attaaaaagg taggtaatta atatgagagt
     7561 aaaaagaaaa aatggaactt ataagcccag gtaaaattgt aagatgtgtt tggtgtggaa
     7621 aaagatttta caagttagat aactctaaag tcatatattg tagtagaaaa tgtgcagcaa
     7681 aagcgagagg ggtgttctaa atgatttttt atgattttga agtattctct tatgactggt
     7741 tagttgtatt tatagatgtt ttaaataaaa aagaagaagt tattgtaaat gatatagata
     7801 agttaaattc attttatata gagcatagag aagatatttt tattggttac aacagtagac
     7861 attatgacca atatattttt aaaggattat tatgtggatt taatgcaaaa gaaataaatg
     7921 attatattat tgttaaaggt caacctggtt ggaagttttc aaacttatta agaaacatac
     7981 aaattaataa ctatgatgtt atgactagtt ttcatggatt aaaacaatta gaaggttttc
     8041 aaggtcatag tataaaagaa tctaatgtat catttaacat tgatagacca ttaactaatg
     8101 atgaaataga agaaactata aaatactgta gatatgatgt tgaacaaact atagatgttt
     8161 ttattgaaag aaaatcagaa tttgaagcac atatgggatt aattaaagct tttaaacttc
     8221 cagtagcata tattggtaaa actcaaacac aactaacagc aattatatta gaagctacaa
     8281 agaaagaaca tgatgatgaa tttgacttac aaataccaga tactctaaaa attgagaaat
     8341 ataaggaagt tttaagctgg tataagaacc cactaaatca tgactattct aaaaatctaa
     8401 aaattaatat ttctaatgta cctcatgtat tcgcttgggg tggtgttcat ggagcaataa
     8461 caaaatacta tggtgaaggt tattttttac atgtggatgt taattccttc tatccaagtc
     8521 ttatgattag atacaattac cactcaagaa atataaaaaa tcctcaaaag tatgttgaaa
     8581 tttatgacaa aaacttacag ttaaaaaaag aaaaatcacc tctaagacca gcctacaaat
     8641 tggcagttaa taaaacttat ggaggaatga aagataaaaa caataattta tatgacccaa
     8701 gacaggctaa taatgtatgt gttagtgggc agctgttatt acttgattta atagagaagt
     8761 tagaaggtca ttgtaaactt attcagagca atacagatgg attaattgta aagttaaata
     8821 caatagatga ttacgaatta atagatgata tatgttatga gtgggaacaa aggacaggta
     8881 tgggtttagg ttttgatgta tacactaaaa tatttcaaaa ggatgttaac aattatttag
     8941 ttataacaga ggatggagaa gttgaagcaa aaggattata tatcaaagat ttaggaaatc
     9001 tagactatga tttaccaatt ataaataaag cacttaaaaa ttatatggta aacaatacac
     9061 ctattgaaga aactataaat aaatgtaatg atttgataga gtttcaaaag atagtaaaaa
     9121 taagtagtaa atattcacat ggtttatata gtccaactat agagggaaaa acaaaaaaag
     9181 tatttattgg cggtaagatt ttaaatgata aatgttttag agtatttgct tcaaaaaata
     9241 aaaatgatgg tggtatttat aaagtcaaaa acaaagaaaa aaatccagaa aaatttgcta
     9301 atacaccaga taaatgtttt atagaaaatg gaagtgttat aggtaaaaaa gtaccaagaa
     9361 agctagataa aacttggtat atagatttag caaatgaaag actcaagcag tttggggtat
     9421 tattaagtaa ttgaggtggt gattggtgag ctttgacata tttaaaggat atataattac
     9481 aaataataaa aaggcagctg agaaatttaa aaatgtaaaa aagttaaaaa cttatgaaca
     9541 gattaagaat ttaccagagt ttgcaggcgt tttagcagaa gaaactgtgt tagttgatat
     9601 tgatgatttt gaaagtagtg aaattctata caaaatagtg caagatttaa agctaaaatg
     9661 tagagtttac aagacaacac gaggtaagca ttttctattt aaaaatacta gtttagaaaa
     9721 gaatagaaca aaatgtagac tagctatagg tttaaattca gatataaaat taggatgtaa
     9781 aaattcctat tcaattttga agttcaacaa tattgaaaga gaaattttat atgatagtaa
     9841 agaaatacaa gagataccaa cgtatttaac tcctataaaa aatggacttg attttttaag
     9901 tcttggagaa ggtgatggaa gaaatcaagc attatataat tatatattaa ctctacagag
     9961 taatgatttt actattgagg aaataagaga aacaataaga gttattaata aatatgtttt
    10021 aaaaactcca ttacaagata atgaacttga agtaattttg agagacgaat cctttcaaaa
    10081 gaagatattt tttaattcaa aaggttcatt tttatttgat gagtttgcta aatacataaa
    10141 aaataataat catgtaatca agataaatga gcagttacat ttatataagg atggtattta
    10201 tgtagatggt caagcaagaa tagaagcaga aatgattaat aatataagca atttaaataa
    10261 ggctaagagg agtgaagtac ttagttattt aaatttatta ataagtgaga atacaagtat
    10321 gtcagaagct aatttaatcg cttttaagaa tggtatatat aatatagttg atgattcttt
    10381 tatagaattt tcaccagaat ttattataac aaataaagtt aactggaact ataatccagg
    10441 agcatattca aagttagttg ataaaactat gaataaatta tcatgtggag attttgaaat
    10501 tagaatgtta cttgaagaag tagtgggata ctgtttttat agacgtaatg agcttagaaa
    10561 agcttttata ttaactggag ataaagcaaa tggtaaatct acctatcttg atatgataaa
    10621 gacattatta ggggatgaaa atacatcagc acttgattta aaagaattaa gtgatagatt
    10681 taaaactgct gaattatttg gaaaacttgc aaatatagga gatgatatag gagatgaatt
    10741 tattgctaat cctgcgatat ttaaaaagtt agtaagtggt gatagagtaa atgttgaaag
    10801 aaaaggtcag aatccatttg attttaacaa ctatagtaag tttttatttt cagctaacaa
    10861 tatacctaga ataaaggata agactggagc agtacttgat agattaatta ttattccttt
    10921 taatgctagc ttttcagtaa atgataagga ttttgaccct tatataaagt acaaattaag
    10981 agagcaagaa gctatagagt atttaataaa tctaggatta gaaggcttaa aaagagtatt
    11041 gaagaataga aaatttacag taccagataa ggttaaaaaa gaaatacttg aatatgaaga
    11101 agtcaataat cctattttag gattttttaa agaagttgat aagatagaaa atgaatcaac
    11161 aaaagaaata tacatgaaat atcaggagta ttgtatttta aatggattac aacctatatc
    11221 aaacgtagaa ttctcaaggc aagttgttaa aaagtttgga tatgaaataa aggacaaaaa
    11281 aattaatggg aaaaaatata gagtattcat caacggttca agatagttca agatggttca
    11341 agatataggt tcaagatgta atgcagtaat atcaatgggg ttcaagatgg ttcaagatgt
    11401 ttttgacctt tatatatatt taagtaaaaa atcatcacaa aaagttgatg attttgctcc
    11461 ctttatataa agaatatata tataatagta tgggactgaa caaatgttct tgactatatg
    11521 tattgaaatt acttaagttc aagaggttca acatctattt tacatcttga accatcttga
    11581 acttgattta attagcaagt tatataatga agtttaatta aaaaaataag ttatatttca
    11641 ttaataactt aacaaaataa ttaaaaagaa aattctgtta atttgcaagg atgtgaaaat
    11701 gaagtgacag actatgaaaa attagaagaa ttgttaaact catatagtaa tttggatatt
    11761 gaaattagag aaatagagtt aaaagtaaga gggagcagtt taagaggaat agaattaaat
    11821 ggaatgccta aaggaaataa tgtttcttca ccaatagaaa atgagttaat atatgttgaa
    11881 agattggaga atgagaaaat atatctacaa attaaaaaag aatcagttaa taatatgtta
    11941 aatttattag atgattttga aagaaattta atagaactaa gatattttaa aaaactacaa
    12001 tataaacaaa taagttatga attaaatata agcgaattgt atgtaggaaa aaagagaaaa
    12061 aaggcactag ataaaatact tccctttgct aaaaaatata atctaatatg aaagtcttgt
    12121 ttatgtccga ttaatgtccg atttatgacc gattaatgat tgatttagta tagaaacatg
    12181 tcacatcaat atactatgag ataagttata atggtagtat gaaacaagtg tataatatat
    12241 cctcttgaaa aaggctaagt acccctaact tagtcttttt tatatttaaa aaaagtgagg
    12301 tggtgatgtg gcaaaatatg aatactggat aacagaagaa ggattaatta agattgaagg
    12361 atgggcaaga gatgggctta cagatgaaca gatagcattt aatattggaa taaatgtcaa
    12421 aacactatat gactggaaaa agaaatatag taatatttgt aatgccttaa aaaagggaaa
    12481 agaagtaatt gacagacagg ttgaaaatgc tttactaaaa agagcattag gttatgagta
    12541 tgatgagata acatatgaag aaggtcaaga aactaaaaga gtaactaaac aagtagtacc
    12601 agatactaca gcacagatat tctggttgaa aaatagaaaa ccagctgaat ggagggataa
    12661 acaaatagta gaatcaacta atgaaattac aataaataat ccgtttaaag aactatctac
    12721 agaagaatta aaaaggttgg caaaattaga tgacgatgga taaaaagtta atacagttag
    12781 aagcgaagaa agaacttgca agacgtgagt tcttttattt ttgcaattta ttagcaccaa
    12841 aattttataa agaagataga aagtatttag ttgaaacctg taataagctt caagattttt
    12901 attattcaga tgatgaagtt ttaattataa atatgccacc tagacatggg aaaagtagaa
    12961 gtgcaagttt atttgtagaa tggattttag gtaaaaataa aaatgaaaaa ataatgactg
    13021 gtagttataa tgagactctt tcaactatgt tttcaaagaa tgttagaaat gctattcaag
    13081 aagaaaaagc cgatatagac actattatct atagcgatat atttcctaac acaaaaatca
    13141 aacatggtga tggagctatg aatttatggt cattagaagg tggttataat aattatttgg
    13201 cgacctctcc gagtggtaca gcaacaggtt ttgggtgttc tcttatgatt gtagatgact
    13261 tagttaaaaa tgcagaggaa gcttataatg agaatgttct tgaaaaacat tgggattggt
    13321 ttactaatac tatgttatca agactagagg aaaaaggaaa aataataatt ataatgacta
    13381 gatggtctag taaggactta gctggtagag tattagaaca ttacaaagaa gaaggtaaga
    13441 aggtaagaca tattaatatg aaagcattac aagaagatgg aaatatgctt tgtgaagaag
    13501 tattatcttt aaagagttat aaatctaaag tgagagctat gggcgaggat attgcgagtg
    13561 ctaactacca acaagagcct attgacctta aaggatgttt atacactaag tttaagacat
    13621 atgagaagct tcctgttgat ggagaaggca atttactatt tacatctatt aaagcttatg
    13681 tagatacagc agatgaggga gcagattact tatgttctat agtttatgga gtgtataaca
    13741 aagaagctta tatactagat gttttataca ctaaggaaag tatggaaata acagagtata
    13801 aaacagctaa gatgttctat aataatgaag ttaacaaagc tgatatagaa agcaatagtg
    13861 gtggtagagc ttttgcaaga aatgtacaaa gaatattgaa agaaaagttt aaaagcaata
    13921 aaacgattat taaatggttt catcagtcga aaaataaaaa tgctagaatt ttatctaata
    13981 gtagttgggt aatggaacat atatattttc caattaattg gagagataag tggatagagt
    14041 tttataaggc tatggtgagt tatcaaagag aaggtaagaa caaacatgat gatgcaccag
    14101 acgctttgac aggggttgca gaaaaggcac tgaaaggtca aggattatca gtatttaagt
    14161 aataatttaa gtaatatagg tggtggtgat gtggagttag aaaaaataag agcaataata
    14221 agtgctgata tagctagaag gcaagagata ttacaggcta aatcatatta ttataatgaa
    14281 aatgatatat tgaaaaaggg tgtagttgta caaaacagag atgagaatcc tcttaggaac
    14341 gctgacaata gaatcagtca caactttcat gaaatacttg tagatgagaa agcttcttat
    14401 atgttcacct atccagttct ttttgacatt gacaatgaca aagaattgaa tgagaaggta
    14461 acagatgttt tagggaatga gtttactaga aaagctaaga atttagcaat agaagcgagt
    14521 aattgtggta ctgcatggct tcactactgg atagatgaag aatatagtgg agaacaggta
    14581 actaatcaaa cattcaaata tggtgtagtg aatacagaag aaattattcc tatatatcga
    14641 aatggaattg aaagagagtt agaagctgtt ataagatatt atgttcagtt agaagatgta
    14701 aaaggtcaaa tacaaaagca ggcatatact tatgttgaat tttggacaga taaaatatta
    14761 gataaatata aattttttgg agtaacatgt tgtggttctc aaatagagca tataacagta
    14821 caacatagat ttaattcagt tccttttatt gaatttgcta acaacataaa aaaacaaagt
    14881 gacttatcaa aatataaatc agtgttggat ttatacgata agataatgag tgggtttgca
    14941 aatgatttag aggatataca gcaaataata tacatcttag aaaattatgg tggagaggat
    15001 acagcacaat ttttaaatga attgaagaga tataaagcaa taaaaactga aacagacagc
    15061 gaaggcgata gtggtggtct taaaactatg caaatagaga tacctgttga agctcgaaag
    15121 gtgatattag agatacttaa aaaacaaata tatgaaagtg gtcaaggatt acaacaagat
    15181 actgaatcgt ttgggaatgc aagtggtgta gcacttaaat tcttttatag aaagttagaa
    15241 ttaaagtctg gactccttga aaccgagttt agaacctctt ttgataagct gattaaggct
    15301 atactatatt ttttaggagt tacagactat aaaaagatac aacaaacata tacacgcaat
    15361 atgatgtcaa atgatttaga ggatgcagat atagcaacta agtcagttgg cataatacca
    15421 actaaaatta ttttaaggca tcatccttgg gtcgacgacc ccgaagaagc tgctttactt
    15481 ttaagagaag aaaagaaaat acaagcttca aaagtatctg atgattataa taactttact
    15541 gaatagaggt gaagttattt gaataataat attgagtact ggaaagaaag agaaaagcaa
    15601 agattaaatt caagattgaa agaagaaaaa gaggtattaa aggaactaga taaacaatat
    15661 aaaattgcaa tgaaaaatat agagaaagaa attgctaatt tattttataa atatgctgaa
    15721 cagaataaat taacatatgc agaaacacaa aaatatttaa ctaataatga atttaacaca
    15781 tggcgcatgg acatcaaaca atatattaaa ttaatagaac aaacaagtga tgaaagatta
    15841 ctgttagagc ttaatacatt agctatgaaa agcagaataa acaggttaga agaactattc
    15901 taccaaatat ctaaagagat aaataataca ttcgacattc aaaataatag agtagaaaag
    15961 ctattagaag aatctgtgaa agatagttac tataagagta tatatgaaac tcaaaaacac
    16021 gttggtgttg gggtaagctt cactaagctt gatagagaag ctttaaagga tataattaca
    16081 tatccttgga gtggtaaaaa cttttctcaa aggatatgga aaaacagaga tttattaagt
    16141 gaagttatca aggaagaaat tactcaaatg gttataagag gagaaagttt gaaaaagatt
    16201 tctaatagag tatcggaaaa aatggactct agttatgaaa atgcaataag attagtacaa
    16261 acggaacatt ctcattttat gtcagaagct gataaaaaag catatgaaag tcaaaaagta
    16321 gataaatatc aattcttagc tacgttacag gataatactt gtaaaagatg tagaagtgta
    16381 gacatgaaag tatatttagt taaagaagcg aaagaaggag aaaattatcc tccgctccat
    16441 cctagatgtc ggtgtacaac tattccatat ttcgaggatg aaaaaggggg aacaaggaca
    16501 gcaagattgc taaaaggtaa gacatatgaa gttcctttca atttatcata taatgaatgg
    16561 tataaaaatc acgttgaagt tgctataaat agagagaagg aaaataaaaa taatgttata
    16621 ataaataata taaagaagga tataaaagat ggcaaatata atctaaatat tcataatggt
    16681 aaacaaggaa agcattttaa ggaccataat aattatacag aaggtaggag ctacttaact
    16741 gtatcaaaag aagaagttca agaacttatt aacaaatatg caggcacagg aatattggag
    16801 cttgatagaa atggtaagtt taaaaataaa gaattaataa catgtgaaaa aaatataggt
    16861 gtaaatataa gcaatctaac aggagaagaa acggaaacta ataagtttta tatacactat
    16921 agtaaaaatg gtactcatat agtgccaaca atgaaaggag ttgaaaagga tgagtaaaaa
    16981 tttaattaat tatatgagtg agaaggttaa aattatagat atagacaata aagaatggat
    17041 tggttatgta aaaacttata caccagctat agatagtgat aatgaaataa atgagattgg
    17101 actaaaacaa gaggattgtt taatatcttt tcaagaagat gaaataaaaa gtatagaaat
    17161 tatatagaaa gcactttcta agtttaaata gtaagtgctt ttattgtgta aaaaattaag
    17221 gaggaataaa taatatggct aagtttaaaa agaaaccagt tgaggtggaa gctttcagat
    17281 tgggctatga tatagaacca gaatggtttt ttgaaaatag tagagtttgt aattttatac
    17341 aagaaaaatg tattgatggt aatgtaagtt gcgatttaaa gacactggaa ggtactatga
    17401 gggctaataa gggcgattac attatacaag gagtaaaagg agaaatatat ccttgcaaag
    17461 cagatatatt tgaaatgaca tatgaaaagg ttgaatatac tgcaactatt gaaaatttaa
    17521 caaactatgc tgaaaatata gaaaaaggac atagatgtgc tgatgaagat aacaacaagg
    17581 aaaataaatt agaactttca gctaagttgg agctagatac aaaagatttt gaggaaaata
    17641 taaaaaatgc gacaaaagaa attgagatat ttaataaagc agtaggcaca ttagagcaaa
    17701 aaattaatgg aatatttggt agagaaaagg taaatgaagt aaaaataaat ataccaacaa
    17761 tatcaaaatc tgaaagtgta gaagaagtaa atggaaagtt acttaaagaa ttaaaatcac
    17821 aaaaacttat agtttcagaa aaagataaaa agttcaaaaa atatgatata tgttttaaaa
    17881 atggtgagtg catatctggt gtaattaaag aacatgtagc tgataaacta accgcttatt
    17941 tttgtgattc tcaatcagat atagattgtt tgagagctat tgaagatgaa gaaaaattgg
    18001 ttatgtttaa cacggctaat gtccaaacta taacaattag tgattatatt gaaaatgaag
    18061 aaattgatta tatataataa tttctttatt ttgtaaaaat gaggtgagtt aaatgagttg
    18121 gttaatactg caaatagtaa gtattgttgt aaatgtaata cttattatca gtttagtaag
    18181 tgatatagtt ttaaaaatat atctaaaaag tttaaaaaaa gaatatgaag tagctataaa
    18241 taaagcttct aatgaacttt tgaaaaaatt aaatgatgaa ctaagaaaac gtaaaagtct
    18301 ataaaggctt ttttattttg ctctttttaa aaaagttgta gagcataaag aacaaagtaa
    18361 ctcctttagt tggagaacaa ctataaaaat ctatggagaa ataagaaggg atgatgatta
    18421 aatggaatgg ttaagaaaaa tattggaaag tattaaaatc gaagaaaata agattgatgt
    18481 tgaggaaata ttaaaaagtg ttaatactga atttcctaag tatgcagtgc ctaaagaaac
    18541 ttttaataaa acaaatgaac aattgaaaga agctaacaaa gctattgaaa gctttaatag
    18601 caaaatgact caagaagatt tagaaaagat aaaaacagaa catcaagcac aaataaaaaa
    18661 gatagaagaa aatcataaga tagaagttga gaaaatgcaa aatgaaagct taaagacaag
    18721 aaaattaagt gctgttgaga aagctttatt aactaacaaa gctaaacaca ctgacttact
    18781 aacaaataag tttgacttag aaaaaataac tataggtgaa gatggcaaga tagtagggat
    18841 agaggaacaa ttaaaagaat tgcaagaaag ctacaaagat ttgtttgaaa gtagtacaac
    18901 tgaaactact actcaaacaa atacaccttt ttataaatat gtaccaggtg ggagtggaga
    18961 aacaaatgaa actgcaaata tggaaactgt agtgaatgga atactaggag ttaaataata
    19021 taattaagag aggatgatta gatggctaat atactagcat acggacaagt tttacaacaa
    19081 ggattggata aacaagcaac acaagaatta ttaactggtt ggatggattc taatgctaaa
    19141 caaataaaat atgaaggagg aaaagaagta aaaataggta agctttctac agatggttta
    19201 ggagattatt caagaggttc agctaatgct tatgtcggtg gagatgttaa atttgaatat
    19261 gaaactaaaa taatgactca agatagaggg agaaaattta ccttagatgc tatggatgta
    19321 gatgaaacaa atttcttagt aacagcaacg actgtcatgg gagaatttca aaggttaaaa
    19381 gtcataccag aaatagatgc ttatagattg agccgtttag cgactattgc tataagtata
    19441 gaaggagaca ttaatgttga gtatggttac acagtaaatt caagcacaat aataaataaa
    19501 ataaaaacag gtataaaaat aattagagaa aatggataca atggacctct agtttgtcat
    19561 ttaacttatg acagtatgtt tgcaatagaa gaaaaagtct tagaaaaatt aacagcagtt
    19621 acttttgcac aaggtggtat acaaacacaa gtgccatcaa ttgatggttg ccctcttata
    19681 aaaacacctc aaaatagaat gtattcatct attttactta atgatggtac tacttctggt
    19741 caaacagcag gaggttattt aaaaggcaca aaagcactag ataccaactt tataatagca
    19801 ccagtggatg tacctcttgc aataacaaaa caagataaaa tgagaatatt tgacccagaa
    19861 acgaatcaaa cagcaaatgc ttggtctatg gactatagaa gatatcatga tttatgggtt
    19921 actgataata aagctaattc tgtatatgct aattttaaag atgctaaacc tacagcttag
    19981 gaagtgattt aaatgtttat attaattaaa gaaaatatag agcgtagcgt agaagattct
    20041 tttttaaaag ataagctaat acaagatgga tttaagttgc tagaagataa gaaaaatatt
    20101 gatatagaaa attcaactct tgaagaactg aaaaacctag caaaagaaaa tggtatagaa
    20161 ggttattcaa agctgaaaaa agatgaatta atagagaaat taaatagtat ttagtttctc
    20221 tattttactt tgaggtgatt aaatgctaga taatataaag ttgattctaa atctaaaaga
    20281 tgatactcat gatagtttaa tagagttgta cattaaaaaa tatactactc tagttcttgc
    20341 atactgtaat atagaaacgc ttaattctac tcttgaaggt attgtagagg ataaagttat
    20401 tgttaagtta aaagagactg tattagtcag tagtgctgat aatggtatta gctcaatttc
    20461 tcgtggtggt tattctgtaa attataatgt tgcaacagct aaaacaacag acgagttgat
    20521 ggaaataaaa ctatctcaaa aggataaaaa tattttgaat aattttagaa aagttaggtg
    20581 gtaaaatgac agaagcagat atactagcac tgacatactt ttgtaaaatg acaataagaa
    20641 ggtgtgtaag cagtaaaaat gaggaaacag gagttacaga ttttaacgag agtcttgtaa
    20701 ttgcagaaga tgtgccttgt ggtttgagtg gaaatatacc taatgtcata gatacagata
    20761 taacaagctc tatctcagta tttgagttat attgtagacc cgaagtggat ttgagagttg
    20821 gagatatact cgatataact ttagaaaatg gggctgtaga aacctttatt gtatctaaac
    20881 catttcctta ttcaagtcat ttacaaacta atctaacttt aaaggaaaga tattaaatga
    20941 tagagtttaa tagtctagac acattaataa gagatttaga aagagaagaa agggaaatgt
    21001 caaagaattt aagaagggct aagaacaata taggtaataa actacttaga aaagtaaaac
    21061 ctaaaacacc agttgctaaa gttgatggag gaacagctag aaagagctgg aagtataaag
    21121 agcttaatct atttgagggt gtagtatcaa ataatgttga atacatttat catttagaat
    21181 atggtcatag aactaggcaa ggaacaggaa ctagcgaaaa ctatagacct aagcctaacg
    21241 gaattagttt tgtaccaggt gtatttatgt tggcaagaag cgttgatgaa atgagcagta
    21301 taattgatga tgaattaaat caaataataa tagatttttg gaattagagg tgatgcgttg
    21361 ttaagttata aagatatact atactcgttt actaaagaat taggtaataa ttttaatgaa
    21421 gatatatttg tagaaggata taacatacaa gacaataaaa agtcttgttt ttttgtgcag
    21481 atattgccag aagtggcaca gacagcgact aaaaagactg acataaaaag ctttttagtt
    21541 gatataaaat atttgcctga ctggaaaaag aaaaaaacag atttatttga tattctaaat
    21601 aaattagaga acatattcac tagaaatata aaagtaaaag atagatattt aactttcagt
    21661 aagaaaaatg gaagtataga aaaagatgaa ataggaaatt atgttcaatt tcttatatct
    21721 ataaattatc atgaacaaat ttattttgaa gaagaaaaac acgaattaat ggaagaatta
    21781 aatatgagat ttaaaggaag gagtgattaa atggctggat tagttaatat aaatatagaa
    21841 tttaaagaac tagctacaag ctttatacag cgttctcaga ctggaatagt agcaattata
    21901 ttgaaagata caacaaagat gtataaagag cttacaagtg aagatgatat accaatttca
    21961 ttgagtgctg ataataaaaa atatattaaa tatggctttg taggggctac cgacaacgag
    22021 aagatattaa gaccaagcaa agttattata agtactttca cagaggatgg aaaggttgag
    22081 gatatactag aagaattaga atctgtagaa tttaattatc tttgtatgcc agaggctata
    22141 gaagcagaaa aaacaaaaat tgtgaattgg attaagaaga taagagaaga agaaagtaca
    22201 gaagctaagg cagtattagc gaatattaaa gctgataatg aagcagttat taacttcact
    22261 gaaaatgtaa cagttggtgg agaggaaata acagcagaaa aatacacacc acgtattgct
    22321 tctcttatag catctactcc aagcacacaa tcaattactt atgctcctct taatgaagtt
    22381 gaatctatta caaagataga taaagctagt gcagacgcta aagtacaatc gggagaatta
    22441 atactaagaa gattgtcagg ggctataagg attgctagag gtgtaaattc tcttacaact
    22501 ctaacacaag aaaaaggaga gatatttcag aagattaagc ttgttgatac taaagactta
    22561 ataagcaaag atataaaaga tatttatgta aaaagttata taggaaaagt tccgaatgtt
    22621 tatgataata agtgtctatt tataattgca atacaagcgt atttagctga attagctaaa
    22681 caagaactaa tagattcaaa tttttctgtt gatattgata tagaaaaaca aaaagaatat
    22741 ttagaaggta aaaaagtgga cacaagtaag atgaaagaag atgaaataaa agaagctaat
    22801 acggattcaa gtggatttta tttaataaaa ttaaaactag ttgacgctat ggaagatata
    22861 aatataagtg ttcaaatgta gaaagcaggt gaaaagatgg caacaagtta tgagcctaga
    22921 aatgttataa atggaacata tggagaggtt tggattaata accaacaaat agctgaatgt
    22981 aaagctatga aagctgaaat aaaatttgat aaagctgaaa tagttagacc tagaaaaata
    23041 ataaaaggtc aaaaaataat tagtgctagt gcagaaggtt ctctaactct atatcatgta
    23101 gattcaaaaa tattagatta tgttacacag attatcaaag aaggtagaga accaaaattt
    23161 acaataacaa gtaaattgtc agacccagat tcttttggaa cagagaggat tgcaataact
    23221 ggtgttagtt ttgatggact tactattata gactgggaaa acggaaaaga aggagaaaaa
    23281 gaagtctcat ttacttttga agattacaat ccaatacaaa caatataaaa ataattaagg
    23341 ataaaaggag aattaatatg agtgaaaata aattagaaaa agaaatggta gataaaaaag
    23401 aaatgacaga ggtaaaaaat gttgtagatt tgttattaag tttagatgct gataaggtaa
    23461 aaatgccatc tataacacat acaatatttt gtaagaaact aggaatagat gtgaactttg
    23521 aatgtaaagc aatagagcca gaattttttg acgagcttca aactagtggt ttaaaaatag
    23581 aaaaaggttc tttaaaggat ttagacaatt ttaaaatgaa atctaatgta atactagcat
    23641 catgtaattt atttaaagat gataaattat taaaacattt tcaatctcca acaccaaaag
    23701 aacttttaag aagaatgtta cttgcagggg aaataaacga attatatgat aaaatttgtg
    23761 aattaaatgg gtatagagat gataacaaaa aagataagga aatagaagaa aaaataaaaa
    23821 actaatcaaa tcggatgaag aaatcaattt aatgtatcta atgtttagat accataacat
    23881 gttgccatcc gattttttta agcttaaata tggtgaaaag catgtaatta gagcttttat
    23941 gtatcaagaa atagatgaaa gaatagaaga aataaagagt tttggaaagg ggttgtagag
    24001 tatgtcagca ggtagtagag ctttagaagc tgttataaga atgcgagatg aagctagtag
    24061 gacgctaaga caagttagag atgctactag agcccttcaa aatcaaacta atacaacatc
    24121 acaagcacaa gaaagattac aagaacaatt tagaaaagta agcaatgcag ctaaaatagc
    24181 aggagtggga attgcaactg gaataggtgc aggacttgtt tctgcatcta aagcaggtgc
    24241 agaatttgaa actgcaatga ctaagacttc gacaatgttt ggagacacta aagtagatac
    24301 agaaaacttg aataataaag tattggagtt atctaaaaat acaggaattg cagcatcttc
    24361 tattggagaa agtctatata atgctttatc ttcgggcatt cctgtcacaa aagatatggg
    24421 gtcagcgatg gactttatga ctaaaaatgc taaattatct aaagcaggat ttacagatat
    24481 agacacagct ttaacagcaa ctgcaaaagt gttgaatgcc tataaaatgg atgtatcaga
    24541 aacagataga gtacacaaag ttatgatgca gacacaaaat aaaggtatca ctacagtcgg
    24601 agaattagga gcaacattag ctcaagtgac tccaactgca tcagcaatga gctttagttt
    24661 tgaacaggta ggagcatcac ttgctaatat gacagcacaa ggaacaccta cagcacaagc
    24721 aacaacacaa ttaaatagtt tacttgctga acttgggaaa actggtacag tagcaaataa
    24781 gtctttatta gatgccacaa aagggactaa atacgcagga aaatctttta aagaattaat
    24841 gcaagcagga gtgccactta atgaaatttt aaatctcatg gatggaagtg ctaaaaagaa
    24901 taaaaaaagc ttaatagata tgtttggtag tattgaagca gggaaagctg cactcgcact
    24961 ttctggtcaa aattcagaac aatatactaa taatttaaaa gctatgtcta cacaagctga
    25021 tgttgtttca agtgcatatg caaagatgtc taatacatta gaatctaaag tggggatact
    25081 aaaagaaagt tttaaaaatc tgggtataga gatatatagt aaactaaaag aacctcttaa
    25141 aaatgcggct gaaacaggga tacaatgttt aagtgactta gataaacagt tttcaagtgg
    25201 gtcacttaaa gcaggtattt cgcaaattgc acaatctttt ggagatttaa catctgcaat
    25261 tataaaaatt gcaacaaagg cattaccaac tatggttaag agtcttagtt gggttctgaa
    25321 aaatggacct actatcgcta gtatttttgt tagtataaaa acagcttcca taatgactag
    25381 tgcagttaaa agtattgtag cattaaaaaa agcttgggtt gcggctaaat tagcagtgcg
    25441 ggtttacatg gttggcatgg cagaagcagg cacagtatta agtggatttc aagttttagt
    25501 tggagtttta actagagaga tgactatagc tcaaggtgta acacaagttt ggagtgctac
    25561 tttagctaca ctaggaggac cagttggtgt tgctataatt gctatagtcg cattagttgc
    25621 aggtcttgta gtcttgtgga atacaaacaa gggttttaga gattttgtta taaatacttg
    25681 gaataatata aaagaaacag ccacaaaagt ttggggtggt atatgtaatt tctttacaca
    25741 aactattcca caagcttgga atgatttatg taccagtttt tcaaatgcag gacaatggtt
    25801 tggagaaatg tggaataata taaaacaagc atttataaat ggctggaatg ctattgtagc
    25861 tttcttcacg caaacaattc caatgtggat taatagcatt ggagtgtggt ttggacaatt
    25921 acctgcaaaa attggttatg gattaggatt tgcattaggg aaaataatat cttggggtat
    25981 ttctgtttgg acttacctag ttacaaatgt gcctatatgg attaataata taggcacatt
    26041 ttttgcacaa ttacctaata aaatttggac ttggctagta agcacagtac aaaaaatagg
    26101 tcaatggggt atggctatga tagcatatgc tcaaatctac gctagaatga ttattaacaa
    26161 catagtagta tttttccaaa ctctacctag tcgcgtatgg acttggctta caaatactgt
    26221 tcaaaaagta gtaagttggg gaagtcaaat ggcttctaaa gggagagaag gagctaaaaa
    26281 attaattact acagtagtag atacattaaa atctttacct aaaaaagtga tggatatagg
    26341 taaaaatatt gttaaaggtt tgtgggaagg tataactgga gctggagatt ggctaaaagg
    26401 caaggtcgga gattttgcaa atggtgtaat aaacggattt aaagatggtt ttggagtaca
    26461 ttctccatct tggaaattac gagatttggt aggtaaattt cttccacctg gtatttggaa
    26521 tggaataaaa atgacattgc caaaattgga gactaatatt actggtatgg ttgatagctt
    26581 agttaaaaga atgtataatc caaaagaagt cgaagaaagt aactatacaa gtaaatataa
    26641 agaagctata gctcaaagaa ccgaacaaaa tactattaat aaaactgaca gcaaaactac
    26701 taataataaa gaaagtaata atattaccat aaatataaat tggggtggtg ttacagttaa
    26761 agaagaagct gatatgacta aattaactaa gatgttagtt aatgaaataa agttaaattt
    26821 agcaggtggt gtatagaaac atagaactct aaaatatgtg agtatgtgct ataatcgtag
    26881 tatatcatta tgttttaggg ggataaatat atggcattat ttagttctaa agaaaattgt
    26941 gtaatatgtg gagaaaaaac taaaaatctg aaaattaaag atggatatgt atgtaaaaaa
    27001 tgtttgcaaa gatgtacagg aatagagtat gtccttaatc ctgcttttgg ttcagcattt
    27061 ttaaataaaa aaaataaaga agttacaaag gaggacattc taggtcttct tgaaaaaaga
    27121 ggtaataatc tagatgagtt agataacttc aacactacaa aacaagtatc tgtttattta
    27181 gaaattgatg aagtacaaag aaaatgtcta ataccagatg gttctatagg gaaaaaaata
    27241 aaccctaaaa ttttttcttt tgatgagatt gtagaatatg aactagtaga agatgaagaa
    27301 agtataataa aaggtggttt aggcaaagca atagcagggg gagtgttatt tggaggagta
    27361 ggagctgtag ttggaggtgt aacagggaaa aagaagacaa agacagttgt aaatagtctc
    27421 aaaataaaaa taacacttaa taacttaaat tatccaaatg tatatatcaa tttgattaca
    27481 acacaaacaa aaacagattc ttttatatat aaaaatgcat atgattctgc acaacaaata
    27541 ttatctatgt tatctataat tcaaaatgga aataatgaaa atagtataga aaaaaataca
    27601 gaaagtaata gttcattaga gcaaataaaa acattaaagg aattgttgga catgggagca
    27661 ataacagaag aagaatttaa tgctaagaaa aaagaattat taaatttata atatataaag
    27721 cacttacttt aacaagtagg tgcttttatt atggaggtga ttgtgttgaa taaaggcata
    27781 aagtttattg gctcattaaa gcgattaaat ttcttaatac aagcaaaaga aaatttaatt
    27841 aaagatatac atgagtattc aaacaatgaa gaagaaattg ctaggtatga aaatttggat
    27901 aaagcttttg aaaaaactat aattgatgaa gctaagtttt taatatcttt agaatagata
    27961 tagaggtgat gtagttggaa atgtggatta gacaagcaaa tgacactttt agatttcctg
    28021 ttttcccttc aagttttgag ataaatagca aagcaatagt aaatacctct aatgtcttga
    28081 aaacaggaga aattgcagta tttggaggtg taggtttaag aactacagaa atatctagtt
    28141 tctttcctaa aaatgaagca agttactgtg attatacagg cttcccatcg ccatatgact
    28201 gtgtaaataa aattcaaaga tggatgaatg aaggttttat attaagattt acaattacag
    28261 aaacgaatat aaattttgaa tgtattataa cagattttca atatgaagaa aaagattgca
    28321 caggggatgt gtattttaca ttaagtttaa aagaatataa aagaatacag atacctaaag
    28381 ttagtacaaa tacagattta tcatcatcaa aagatgtacc acttacaaaa ggatttgaag
    28441 ttaaaaataa acagagaact cataaggtag gtaagggtga cagtctttgg agtttggcaa
    28501 aaaaatatta tggcaatggg gatttatgga agaaaattta tgatgctaat aaaaaattaa
    28561 ttaaaaatcc agatattata aaagatggtt gggttctagt aattccttaa gcgaggtgat
    28621 agagttggat aaattaagaa taatatcaga aagcaatagt ttaacgaaag aggatttaac
    28681 agaaaaagac ttgtattgta taggcaagtt tatacaaatt ggagctataa aaagcttcat
    28741 gcacaatgaa aaagacttag atttcccttg tacagattgt aaatactcag ataaatgttt
    28801 tggagataat agagaatcag atttttggga tactttttta aagttaagta aattgactga
    28861 tttaaaatta tctccattta aaggttttaa cataaattaa tcacttataa atcgaaaaga
    28921 caagaaggtg atttagatta ataatataaa attacaggtc catataaaaa atggagctat
    28981 atacaacata acagatatag tagaaaaggt aacttggtca ggtgattata agtcaccatc
    29041 aaggacacta gagttttcta tagtacagtc agcttctgat attaatttta ggcagataga
    29101 cataccaata gctagtacag tatgttttta tgtagatgat aaagaaatct atagaggaat
    29161 gataattaat aggtccaaag actctagcaa caatagtatt agcttcacat caaaagatat
    29221 gggtttttta cttactcaaa gtgaagtatc atataacttt aaagataagt tagttgagga
    29281 cattgcaaaa caagtattta atgacaataa acttgcaata ggaaatatac ctaaaactaa
    29341 tgttaaatac actaagatgt ttattggtgt aactggttat gataccataa tgagtgcata
    29401 tacagaggct agtaagacaa cgaagaaaaa gtatatgata gagtctaatt tagataaatt
    29461 taatatcatt gaaaaaggta cggttacact aaatgt
//
LOCUS       DAYAOO010000048        28791 bp    DNA     linear   BCT 12-OCT-2024
DEFINITION  TPA_asm: Clostridioides difficile isolate ST8-SSI-h139-18
            SAMN40601845-rid21577343.denovo.048, whole genome shotgun sequence.
ACCESSION   DAYAOO010000048 DAYAOO010000000
VERSION     DAYAOO010000048.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN40601845
            Sequence Read Archive: SRR28438827
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 28791)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 28791)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-MAY-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-MAY-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002157583.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002157583.1
            Genome Coverage       :: 163x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/11/2024 16:19:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 4,038
            CDSs (total)                      :: 3,963
            Genes (coding)                    :: 3,930
            CDSs (with protein)               :: 3,930
            Genes (RNA)                       :: 75
            rRNAs                             :: 6, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 60
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 33
            CDSs (without protein)            :: 33
            Pseudo Genes (ambiguous residues) :: 0 of 33
            Pseudo Genes (frameshifted)       :: 7 of 33
            Pseudo Genes (incomplete)         :: 25 of 33
            Pseudo Genes (internal stop)      :: 11 of 33
            Pseudo Genes (multiple problems)  :: 8 of 33
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..28791
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN40601845-rid21577343.denovo.048"
                     /isolate="ST8-SSI-h139-18"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Denmark"
                     /collection_date="2018"
                     /collected_by="Statens Serum Institute"
     gene            53..928
                     /locus_tag="ACGI5H_002338"
     CDS             53..928
                     /locus_tag="ACGI5H_002338"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861406.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="kinase"
                     /protein_id="HFG9698039.1"
                     /translation="MITFDVNGAIIRFDDTKNNYNKIRKIFKLYALEISKNFERDCLN
                     SFQNLKQISDRGLSLGEKYIEESFKKGIETIVSFGIITIDINTFKSVYCEKYLDFKRL
                     FNNLNKTFIIPNKNKKNGHASFLEIESTIKKMSNYLYNDCFKIHYAVVDALIENRITA
                     VHSYIDEESIKKSNALFNNYKDGFIGKADECKVVKQIITLNPYREDVYEFLVKEDGDF
                     SKEIERLTEFLGYDIREYKASLMDIYINELMESDENDVENAKEKIEKYARYIGCSDEN
                     LYVARVNAIYTFANA"
     gene            1287..2591
                     /locus_tag="ACGI5H_002339"
     CDS             1287..2591
                     /locus_tag="ACGI5H_002339"
                     /EC_number="3.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="acyl-CoA thioesterase/bile acid-CoA:amino acid
                     N-acyltransferase family protein"
                     /protein_id="HFG9698040.1"
                     /translation="MKVNVYNVESFVDERLKIMVSDLIPNTKLKISVKMEFPWCKGEE
                     FSSYGVFCSNEKGEVDLDLVEPIEGTYKADNCMGLIYSLEKSKTEGKNFAENISIDKP
                     IIMNMIFETSIERKEVELKRIFKSEDITTKYISDEFIGKLFYKQNSNNKTILMLGGSD
                     GNLDALDLLAAPLASRGFNVLTVAYFALEGLPDKLEEVPLEYFEKVFEWISENEITST
                     KEIFVHGTSKGGELAFLLASRYEQIKKVVVSQPHIYCFQALNGLMSGNDTSSWSYKGE
                     PFPYIKVDNDIFFEEQKKNISKGIPFGFNSTYKKSLKRAENRKEARIKIENSKADILM
                     IAGKEDNIWNSYEACLKALEIFEENNYPYNVELLTYNNMGHPLPIPYIMPLKETLCMS
                     MSGGIFSSGGTVEGNSKGQFESWNRTIEFYKKPLSSDLNNYY"
     gene            2775..4166
                     /locus_tag="ACGI5H_002340"
     CDS             2775..4166
                     /locus_tag="ACGI5H_002340"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889936.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="benzoate/H(+) symporter BenE family transporter"
                     /protein_id="HFG9698041.1"
                     /translation="MERLARREQPHIKFGMFKIRIPFIHYRFEKPEAIQGIISSMTSL
                     GTIGLSTQILGLPYEVAWSMAIINSILYCLHVFMGDPVVPGWITASITLTTAYLLKFS
                     MGIERIQALTALQIDLGIIFILMGITGVAGKLVSKIPNSIKGGILMGVGISTIISEFN
                     PKGRFDSYPISITVGILVACFVMFSERFDTLKVKNKFLFHLGEYGVVSAILVSLIVGI
                     FSKEIEIPRFSFDNLVYIVDFKNLINTVSPFGIGFPSVMLFIQGIPMAFMIYIIAFGD
                     FITGENLVLSESENRKDEYIDFNSNRSNVISGIRNIFMAIFSPYIPMCGPLAATLTGS
                     VAQRYKVGKEAMQSVFSGMGTLVWVSAIFICFYPIAQIATPLIPLALSVTLLVQGYLC
                     TKLSMELCNTGVEKGLIGLMGGVIAAKGGTWGLAVGFILYFILIDSKKRKEKDINSIE
                     DCVYEILDKKKSI"
     gene            4343..4930
                     /locus_tag="ACGI5H_002341"
     CDS             4343..4930
                     /locus_tag="ACGI5H_002341"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729026.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HFG9698042.1"
                     /translation="MPPKVKITKEMILNTVLDITREVGFEAVNARSIASKLQCSTRPI
                     FTCYENMNELKNEFLAFAYEYYNQYVVNYRNSKSVSPYLLLPLSYIEFAQEETYLFKL
                     LFINDLDLMMKEANDFYKEIDNEKKARLFSESIGIDLECAKVIFLDLFLYTHGIAVLT
                     ATKKLTLDRYSAEKMLKNILTAFIRQEKSDWNLSI"
     gene            4963..5754
                     /locus_tag="ACGI5H_002342"
     CDS             4963..5754
                     /locus_tag="ACGI5H_002342"
                     /EC_number="2.1.1.222"
                     /EC_number="2.1.1.64"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424121.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008425 -
                     2-polyprenyl-6-methoxy-1,4-benzoquinone methyltransferase
                     activity [Evidence IEA];
                     GO_function: GO:0061542 - 3-demethylubiquinol-n
                     3-O-methyltransferase activity [Evidence IEA];
                     GO_function: GO:0102208 - 2-polyprenyl-6-hydroxyphenol
                     methylase activity [Evidence IEA];
                     GO_process: GO:0006744 - ubiquinone biosynthetic process
                     [Evidence IEA];
                     GO_process: GO:0032259 - methylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HFG9698043.1"
                     /translation="METKQYLIDFYNTYDEDSRLALKHGMVEFLTTMHYIDKYIKSGD
                     CVLEIGAATGRYSHTLARQGYDVDAVELVEHNIEVFHKNTQSNENISITQGNAMDLSV
                     FPDNKYDITLLLGPLYHLYNKEDKQQALHEAIRVTKPGGVVFAAYVISDGCLIDEGFH
                     RGNINVSEYIEKGLIDPQTFAAKSEPKDLFELVRKENIDDLMSAFNVTRLHYVASDGL
                     ALYMREAVDSMDDDAFALYLKYHLATCEREDLVGVTSHAIDIFRK"
     gene            complement(5935..8352)
                     /locus_tag="ACGI5H_002343"
     CDS             complement(5935..8352)
                     /locus_tag="ACGI5H_002343"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861404.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="FtsX-like permease family protein"
                     /protein_id="HFG9698044.1"
                     /translation="MFRNNNRTFIRKIALNDLKINKLKTYLSGIIIMISTCLLLTVTL
                     VSYNASVDLVNASPYHAIYKSVDEKAKNILYKDKNFSGVGTYKLIGSNKKTDCIMSIV
                     YADDTAIKLMNFQPLKGKLPTNKNEIAISEKYLQEFGLDKDIGDSIKLNYYDDITNKE
                     VQCDFIIVGFLENYYQDNAKQYYTVVSNDYFKNIASTPLQNKSNTFDESRPDTVDVLV
                     KLSEENTEKDSASIKTQLNKIGLSLGIKKYNIYLNDNYIESNLIDGEQIITVLVVGIV
                     VLFSSVFVIYSIFYISVVNSVQMYAKLKSLGMTSFQLKKIISLQGNILSIIFIPLGVI
                     ASCIIAYIIQPLAWQMIADLFIILILSLVMFLTVRISLFKPARIISKISAIEAMQYTE
                     TKFRKKAKNFSYINIKNLALKNIESNRKKNLIALISLSISGVLFISIANLANSIDFKK
                     QLSQQFVYNEDYIISIKSDNLYEHITEIQQNNPLTDSLKNEIKSIHGVKKLIESKSIK
                     SNIIEPYIKDRDEKQFITLIKGITPELSKSLEEYIVSGKIDYTHLDSDSLIINKYRTK
                     YYGLNLKVGDTVTFNIFSGNDIIKKKMKIIGIIDNSNTGGMFFASDKTLESLTPYNTN
                     LDFSILIDKKHSKEVEEKLLSIIQKNSNLMLYSYEDDYRMITRAFQYIIIASYIFVGL
                     ISCFGILNMTNTLINSVLIRKKEFALLQAVGMTRKQLRNMLYREGLNISIKAICTSSI
                     LGYFGSNLLCTFIKDVIRLDFINFKFSIFTILIFSFVLIGIQVLVTELLVRNIEKKSL
                     TERLRSQ"
     gene            complement(8365..9030)
                     /locus_tag="ACGI5H_002344"
     CDS             complement(8365..9030)
                     /locus_tag="ACGI5H_002344"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435295.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HFG9698045.1"
                     /translation="MSILQVINLKKYYGQSSNITKALDGVTLSIEKGEFISIVGTSGS
                     GKSTLLNMMGGLDNPTSGKVIIKGKELSTMSDEQLTIFRRRNIGFIFQNYNLVPLLNV
                     YENIILPIGLDGETIDKDFINEIINMLSLEEKLYDIPSNLSGGQQQRVAIARALVTKP
                     AIILADEPTGNLDSRTSSDVLSLLKVTSKKFNQTIVMITHNNEIAQLTDRIIRIEDGK
                     IVN"
     gene            complement(9112..10143)
                     /locus_tag="ACGI5H_002345"
     CDS             complement(9112..10143)
                     /locus_tag="ACGI5H_002345"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897094.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing sensor histidine kinase"
                     /protein_id="HFG9698046.1"
                     /translation="MNFKKFSFSSIYLIIAVGIIFTAILFSISIYLITDDLKLIALLL
                     IYTIVLCGFIALIIFLLHKKIVIFCSRICHTLDSMMNSEDNIEIELEEETILSRINHR
                     LIRMYEVIQENRNSIAIEKADLQELVSDISHQIKTPIANLKMINTTLLNQTFKTEIQK
                     DFLMDMENQLDKLDFLMQSMVKTSRLETGIITLSKKKNSIYETIATALSGILFDAEKK
                     NIEVTVDCDPNLYIIHDKKWTSEAIFNILDNAVKYTSSNGKIRVATECWVMYTKIDII
                     DNGKGISESRQAEIFKRFYREEDVHDIEGIGIGLYLSRKIISLQGGYIKVTSDIGKGS
                     TFSIFLPNK"
     gene            complement(10133..10819)
                     /locus_tag="ACGI5H_002346"
     CDS             complement(10133..10819)
                     /locus_tag="ACGI5H_002346"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435302.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000156 - phosphorelay response regulator
                     activity [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HFG9698047.1"
                     /translation="MEKILVVEDDSILNKTLSYNLIEDGYIITSKFTAKSALKSIFEC
                     EFDLIILDINLPDKSGFELCNEIKENYNIPIIFLTANDMECDMIKGYELGALDYITKP
                     FNINIFKQKIKAFLNHLTIKTKQDYYRDGYLEINFSELSANINGNQIIFTPLEYRTLK
                     LLTENPKSILTRKVLLEKLWDIDANFVDEHTLTSVISRIRSKIEKDNLKYIKTVYGMG
                     YMWLGERNEF"
     gene            complement(10977..12041)
                     /locus_tag="ACGI5H_002347"
     CDS             complement(10977..12041)
                     /locus_tag="ACGI5H_002347"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902862.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="reductive dehalogenase domain-containing
                     protein"
                     /protein_id="HFG9698048.1"
                     /translation="MKRVDERNTMFARANYKKDSTAYNDYYKKNPDKKEIDDSIRNRP
                     NLCSEGTMTYNELNSPMASSAFDFLSDIKSLCEGKVSDTKVDVDAKSMTKKIKGLAKQ
                     YGASVVGITKLKDYHIYTNRGRHEENYGEEINLTHKYAIVFGCEMDKEMINRAPMICE
                     VIETSKCYVDASIVGMILSYYIRNLGYDARNHMDANYLVMPVFIARDAGLGDIGRNAI
                     LTNKDYGSRLRLGVVTTDIPLLEDEYVDFGLEDFCKVCKKCSFNCPSHSLSNDIKIGD
                     DGKYNWVIEHETCYIKWRYLGTDCGMCISACPFSQNLETIKNTTSFKGNNELIQKALD
                     EYTSKFGKRIFIPGNPSWLK"
     gene            12303..12974
                     /locus_tag="ACGI5H_002348"
     CDS             12303..12974
                     /locus_tag="ACGI5H_002348"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889923.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000156 - phosphorelay response regulator
                     activity [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HFG9698049.1"
                     /translation="MNLLIIEDDINLNEGLFYAFENDGFNVFKAYTKQEGLNIFNSKN
                     IDFIILDCNLPDGDGFDVCQIIREKSDIPIIMLTARDSEIDEVKGLEIGLDDYITKPF
                     SLSVLKARVKVAIRKKSNNKVIYSNGIKLDQKLLKVYKNKECLELSSVEYKLLSYLIE
                     NKGQILLKEQILHHIWDSEENYVDDNIVSVNIRRLRVKVEDDPSNPKYIKTAYGMGYL
                     WNEVE"
     gene            12976..13884
                     /locus_tag="ACGI5H_002349"
     CDS             12976..13884
                     /locus_tag="ACGI5H_002349"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435311.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing sensor histidine kinase"
                     /protein_id="HFG9698050.1"
                     /translation="MFILAFIICTVVIFIVSTKINRKRYDELNLMLNQILEGKEVTYP
                     DTKDTRASKISHQVKKIKDMIEIEVEQSKSEKEAIKGLISNMSHQLKTPLSNITIYCE
                     LLENINISTLQKKEFLQKMKNETFKIDWLLQSLFKMTKLEDGVIEFEVEELLIKDTLI
                     QSISTIFNKAEAKNIRINLEPFSDIKLVHNKKWTIEAIVNVLENAIKYSPSDSTITIS
                     VIKMELYTKITIKDEGIGIDSRELNDIFKRFYRSKNVENQNGTGIGLYLTRLILEKEN
                     GNIIVESKLGSGCCFSIFLQNCKSLN"
     gene            13961..14647
                     /locus_tag="ACGI5H_002350"
     CDS             13961..14647
                     /locus_tag="ACGI5H_002350"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HFG9698051.1"
                     /translation="MSILVTNNLVKHYGKGETKVKALNGVSIEIERDTFTAIVGTSGS
                     GKSTLLNIIGGLDNPTSGDVIIKGKNISKIGKKDLTVFRRRNIGFIFQNYSLMPVLNT
                     YDNIALPVTLDKGNHIDHEYIEMLMKTLGIWDKRLKFPSELSGGQQQRVAIARALANK
                     PALILADEPTGNLDSKTTMEVVCLLKESSAKFHQTILMVTHNENIAQVCDSIIHIEDG
                     VVVNTGGEVL"
     gene            14644..17199
                     /locus_tag="ACGI5H_002351"
     CDS             14644..17199
                     /locus_tag="ACGI5H_002351"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="FtsX-like permease family protein"
                     /protein_id="HFG9698052.1"
                     /translation="MMSLVKFSIQYIKHYKKQSISIVLSIVLSVALLTGIGSLVHSAD
                     KSRIEKIREDSGDYHYFYKVDKEQLNKIKKNKKSKEYTVDRLGVTKPKNQIDEPFIIE
                     FLNADSSYLDMTGRKLLKGTLPSKDGEIVLDTYSLNNLNVNKEIGTEINLDGKIYKLC
                     GILSSLSNPETALEGFVNDYFQPKEKDSYIVYVKYDENKNIKKQNYKFMKKFNISKEK
                     TYINWPLSVEFGVKPPKNIEKYNIFEFLKNLELNTNAIILLVGVFGAAAVYSIFHVSI
                     LQRISQYGVLEVLGANNKQLLFLLFLELFLLFIVGFPIGCFLGIEVASTIYEQFPHIF
                     LSSDIVPGAFFISEKSIYLGFLFILLLLILIAVRVVHQLNKYSSIESMKNFKITNKKK
                     RILESVKHSNMTKVLSHKYMTQKKGMFIGILFSLSLGGIIFLCSSYSIQLTKNNNELT
                     MKADDGLNSDYQITMQTTDFDVGIPKDKISRLNNVEGISKVYPVRYLFGAMQIKEEQL
                     FWKNFFKPLEKDYRIKTFFDGICTKQNEGGYLLKTNIYGYNNGMLEGLNSYIIDGEIN
                     THDMVKNNKVIVRLPMDGTGMYDAVDINPGDTIKVKVPKTMKPTDEIVKFKEENKNDY
                     TTKEFVVAATVKRVMANNIYFIGDYGMDIVMTNGQMKNNFDIENYNSVSIKKTEDSNS
                     EELSENIKSVVSDVKRCIVTDYTIAIEKNNTYLNQKLLFIYGIVFVLLAISLFHIINT
                     VSYLIFSRRHEFGILRAMGITDNKFLLMMIREGFLYGFYASIIMVIGSVIGQFMIYFM
                     VKRVYLYINPILKINTPLYIGMIILNITISIVAVIIPVRQILKSDIISEINKN"
     gene            complement(17393..18592)
                     /locus_tag="ACGI5H_002352"
     CDS             complement(17393..18592)
                     /locus_tag="ACGI5H_002352"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003493023.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="coenzyme F420-0:L-glutamate ligase"
                     /protein_id="HFG9698053.1"
                     /translation="MDRLVGTVSRGVRAPIIRQGDDLVKIVVDSVLNASKSENFEVRD
                     KDVIAVTEAVVARAQGNYAHVDNIAKDVKDKFGDDTVGVIFPILSRNRFAICLKGIAK
                     GCRKVVLMLSYPSDEVGNHLISIDELDDKGINPWSDVLTEEKYRELFGYNKHTFTGVD
                     YVDYYKNLIKDCGAEVEIVFANNPKTILNYTTSILTCDIHTRQRTKRILRQNGAKKVY
                     SLDDIMTASVDGSGYNDQYGLLGSNKATEETVKLFPINCDEVVNKIQGNIKEITGKDV
                     EVMVYGDGAFKDPVGKIWELADPVVSPAYTKGLEGTPNEVKLKYLADNDFADLSGDEL
                     KEAISKYIVEKDNKSDDLTGNMVSQGTTPRRLTDLIGSLADLTSGSGDKGTPIIYIQG
                     YFDNYTK"
     gene            18711..19598
                     /locus_tag="ACGI5H_002353"
     CDS             18711..19598
                     /locus_tag="ACGI5H_002353"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435316.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HFG9698054.1"
                     /translation="MNIKLELYKVFNAVVNNKSFSLAAKELFMSQPAVSQSIKQLEEQ
                     LDTLLFYRNNKGVKLTPEGKILSEHVTTALKLISSGEDRINKFKKLEYGSLKIGVGDT
                     AARFFLLKYLEIFHKKYPHIHVSTINRTSRELISLLKDGNIDIAIINMPIEDDTLNIV
                     ECIEIHDIFVCANDYIEYKGRKISLEELNTLPLIMLENKANSRLYVNEYFLSKGIKLN
                     PDIELGSHELLLEFAYINLGVSCVIEEFSIDYLENEKLFKLDIKEPIPKRNIGYCHLK
                     DISLSLATKEFLSMISNNI"
     gene            19788..20345
                     /locus_tag="ACGI5H_002354"
     CDS             19788..20345
                     /locus_tag="ACGI5H_002354"
                     /EC_number="2.3.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905633.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:0016746 - acyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HFG9698055.1"
                     /translation="MSDSEYPQMKTLETRSCILRPASLDDVEDFFDCYKNKIVVKHLP
                     FSEHKSLEDTRKFIKSFFLNPYKKGKIGHFAIVYKRDNKVIGNMGFNNINPKALEAEI
                     GICINPSYWGHDFATEITKRVIQYGFRELNLNKIIAITYEENQNSTKSLDLLGFKCTG
                     KYIKKIHTGNTVKNVPCYQYELKKQ"
     gene            complement(20584..21444)
                     /locus_tag="ACGI5H_002355"
     CDS             complement(20584..21444)
                     /locus_tag="ACGI5H_002355"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435320.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HFG9698056.1"
                     /translation="MKKQKSPILLEMLGLFFGCISMSIGINMFLKPHTIAPGGLSGLS
                     LVLNKVTGLPVSAIMLIIGVPLVILAFRIMGTKNSLKTLFGTVVFSAIVQLTDPLSKL
                     RFTNDLLLSSIAGGILVGIGLGIMFKSDASTGGTDLIALILSKKFPGIKATKFMSCLD
                     GMVVISSGIVNRSLETALYSGIALCVLIKIADMIMEGFDHSKAFFIISDEPESLRQAI
                     TEELDRGLTILDGKGGYTRENKEVLLVVVSKKQELYLKRLVKRTDPTAFVIVTDVHEV
                     LGEGFKNLEN"
     gene            21943..23346
                     /locus_tag="ACGI5H_002356"
     CDS             21943..23346
                     /locus_tag="ACGI5H_002356"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729034.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing sensor histidine kinase"
                     /protein_id="HFG9698057.1"
                     /translation="MHKPSYKTVFHSYIIFFMIFICLILTVIGIFLSLITIQKPNGEF
                     IRSDWPKKFTENFNEQIVFIDNKPQVKQSGLEKLRENQLWLQILDSSGNRVYGFLEPK
                     EHKDYYSNSELLALANQNNSSNGTVYFNTIKNNKNDYIYIIYFPLNISKVNMFFDGGK
                     FIGGKSIVFSIIGIIFLIILVSGIAYGYWVTKCISNITSAVSDISKRSYLPVNIKGVF
                     ADIYNSLNILNEEIHKSDEIQNKTDIMREEWISNITHDLKTPLSPIKGYAELLTDSST
                     NYSPEKVYKYASIMLKNIEYTNTLINDLKLTYQLKNGIIPLNKNNYDLVRFLKELSID
                     ILNYPEYESNIVEFKSNIDNINFDFDCTLLKRAFSNLIVNAFTYGDKNTKVCVHVTLN
                     ERIEIIISDNGKGMSREEASNLFNRYYRGSNTKQKIEGTGLGLAITKQIIEVHGGNIS
                     VESIPGLGSSFYITFPI"
     gene            23565..26042
                     /locus_tag="ACGI5H_002357"
     CDS             23565..26042
                     /locus_tag="ACGI5H_002357"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902855.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="FtsX-like permease family protein"
                     /protein_id="HFG9698058.1"
                     /translation="MKIILKYIFTNIKERKIRTAVMLLSIVLSTVLLFVSFSIGLSYE
                     SAQRKMAKGMYGTATISVQSKNPDILTNLEDIPDLNTIKSKVGVLESSAIYNKGGYYE
                     EFSLISADLSQLNKINKPRLENGDSITDFSGDKIILPNRFTSKYKIKKGDSITLQIYG
                     KSYTFQVSDIASYDTVFLRNTRGVNALLPKETLSKIINKGSGYTRVLIESEEEITENL
                     VNKLSEELSTEKYMVSNTINETKIISDARQKTMPFFLISFFALTLSIFIIYSSYKVIT
                     LERLPFIGTFRSIGANEKTVTRILMLESILYGSIGGLIAIPIGVVVLNLMLHGLGNSL
                     EQGISIPVVISPIGVIISVIVAIIVSSFSAYIPVKKASHLPIKNIVLGTVEEKNVSNR
                     SILFIGSIMFILSILLPRISPENTLYLAGGFSLLGLIVATIVLIPLITDIMSIVFEFV
                     YKNILGNEGKLAARNMKNNKNIIQNITLLFISISAVIAISVVGNFVKTYITDVFRDAE
                     LQGFADGNMNEEFIEDVRHMEGIKKILPLYVMNNEISGNGVTLSRLEGTDNIKLYNSM
                     FGINYTNFEIKKQVIEAFNDKRSVILNEDTLKKVGLSIGDTITLSNDKYDFSYKIVGS
                     FKSRANDVEAVIPSHYAVNDFDKTNYGFLVYTAVNPDAVMIQIRYLFGDTYNWSRTVE
                     EFNNDSLNTISSFLSPMNKMTYFIFLLATVGIINNLLINYIQKRRSIAMYKSIGLSNK
                     QNIKVTLIEGVTSGLLGAVIGIVISILEIQTIFIVAGPKISMKPDLDFKTFIIVGLLG
                     IIVTLIGSIVPIIKGKKMKLIEEIKFE"
     gene            26057..26743
                     /locus_tag="ACGI5H_002358"
     CDS             26057..26743
                     /locus_tag="ACGI5H_002358"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729037.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HFG9698059.1"
                     /translation="MKITHNSLAVEAKNIIKEYKIGNTTTRVLKEVSLQVMKGEFVSI
                     MGQSGSGKSTLLYILGGLDTPTSGKVYMNGADISHFNDEKMSIIRRRNIGFVFQFYNL
                     IPNLNVEENIMLPLLLDGKNLKDYKNQLDEILDIVGLTDRRKHTPRELSGGQQQRVAI
                     ARALIGKPEILFADEPTGNLDSKTGIEIIDLLNKINRDNGQTIIMVTHSPEAAKSSSR
                     TITVSDGLIV"
     gene            27017..27850
                     /locus_tag="ACGI5H_002359"
     CDS             27017..27850
                     /locus_tag="ACGI5H_002359"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902854.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_function: GO:0043565 - sequence-specific DNA binding
                     [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HFG9698060.1"
                     /translation="MLKKESIHFINKNRSLIVCEDNFVYLLPCIQLRNWISNFTISFP
                     NQTIISDNYTIIPHGSVTLVFFYDATGLHSLLFGPTTKPKTVGNIANRCDVILIIEFQ
                     PAGFFPLIGIQQSELIDKVVPFSIINTSLDLEIKKIFNESLSIDKLILKLEELLISNI
                     KIEYSYEFILAIQLIIQNSGNISSQEISKKVFYSSRHLNRLFNQYLGLSMKSFSRLVR
                     INKSIKLLNNNKTSWMSICNELGFYDIPHFIKDFKIVCGITPQKYRANMSDFYSEIAK
                     F"
     gene            27888..28349
                     /locus_tag="ACGI5H_002360"
     CDS             27888..28349
                     /locus_tag="ACGI5H_002360"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889914.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HFG9698061.1"
                     /translation="MKFGGVLLIVKDINKSKKFFEDVMEQKITLDLGEHVSFENGFGL
                     QSNYKAIIGYDLPIYQQSNNFQLYFEVNDIKQWESKINRIGNIEFLHYIKEYPWGQRT
                     FRFYDFDKNIIEISESMESVIKRLLKQGLALEEISKRTMYPVEFITQFQQV"
     gene            28380..28628
                     /locus_tag="ACGI5H_002361"
     CDS             28380..28628
                     /locus_tag="ACGI5H_002361"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435328.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HFG9698062.1"
                     /translation="MQKTKAWGIIEPEKPESQQQMAHMDFAVKDLEEAVQYAIHCGAT
                     IAEEQFTDDWRVMIDPAGHPFCLCQMKSIMESSHFSLL"
BASE COUNT        10859 a         3455 c         4232 g        10245 t
ORIGIN      
        1 gtttatatta aatttatttt attgatgaaa ctaatgggga ggttaaaact caatgattac
       61 ttttgatgta aatggagcta ttatcagatt tgatgataca aaaaataatt ataataagat
      121 aaggaaaatc tttaaattat atgctttgga aatatctaaa aactttgaga gagattgttt
      181 aaatagtttt caaaatctaa agcaaatatc tgatagaggt ttaagtttag gagaaaaata
      241 tatagaagag tcttttaaga aaggaattga gactatagta agttttggaa ttataactat
      301 agatatcaat acctttaaaa gtgtttattg tgaaaaatat ttagatttta agagactttt
      361 taataacttg aataaaactt ttattatacc aaataaaaat aaaaaaaatg gccacgcgag
      421 cttcttagaa atagaatcga caataaagaa aatgagcaat tatttataca atgattgttt
      481 taaaattcat tatgctgttg tagatgccct tatagaaaat cgtataactg cggtacattc
      541 ttatattgat gaagaatcta taaaaaaatc taatgcctta tttaataatt ataaagatgg
      601 ttttattggg aaggctgacg aatgcaaagt agtaaaacaa ataataactt taaatccata
      661 tagggaagat gtatacgaat ttttggtaaa agaagatgga gattttagta aggaaattga
      721 gagattgact gaatttttag gctatgatat aagagaatat aaagcgtcat taatggatat
      781 ttatataaat gagttaatgg agagcgatga aaatgatgtt gaaaatgcaa aagaaaagat
      841 tgaaaaatat gctagatata ttggatgtag tgatgagaat ttatatgtag caagagttaa
      901 tgccatatat acttttgcaa atgcataatt ttattaaaca ttaaatatta gatgttcgat
      961 tatataaatt taaataaaaa aatatcctta ttaataacaa atagtttata ttaaaaacca
     1021 ttcttaaaat gagtggtttt ttattttgaa tatatatatt ctaaacctaa tagcattcct
     1081 atctttaatt agccaaaaat caactggatt tcatatagac tacataattt taaattgcta
     1141 aaaaagacaa tatgttgaca aaaatagaat atgttgataa aatgaaatag tcaatatggt
     1201 gtcttaattt aaaaatttat ttatgttgta ttagataaag ctgttttata taaaacataa
     1261 ataattatta taaggagaaa tagattatga aagtaaatgt atacaatgta gaatcatttg
     1321 tggatgaaag acttaagatt atggtttcgg acttaattcc aaatactaaa cttaaaataa
     1381 gtgtgaaaat ggaatttcca tggtgcaagg gagaagaatt ttcatcttat ggagtgtttt
     1441 gttcaaatga aaaaggagaa gtagatttag atttagttga acctatagaa ggtacttata
     1501 aggctgataa ttgtatgggg ttaatttatt cgctggaaaa atctaaaact gaaggtaaaa
     1561 attttgcaga aaatatatct attgataaac caataattat gaatatgata tttgaaactt
     1621 ctattgaaag aaaagaagtt gaattaaaga gaatatttaa atcagaagat attaccacaa
     1681 aatatatatc tgatgagttt ataggaaaat tattttataa acaaaattct aataataaaa
     1741 caattttaat gctaggtggt tctgatggaa atttagacgc tctagacctt ttagcagctc
     1801 cacttgcatc tagaggattc aatgtactaa cagttgcata ctttgcttta gaagggttac
     1861 cagataaatt agaagaggtt ccattagaat attttgaaaa agtatttgag tggattagtg
     1921 aaaatgaaat taccagtact aaagaaatat ttgtacatgg gacatcaaag ggtggagaat
     1981 tggccttttt acttgcttca agatatgaac aaattaaaaa ggttgtagta tcacaacctc
     2041 acatttattg tttccaagct cttaatggat tgatgagtgg aaatgatact tcatcatggt
     2101 catataaagg agagccattt ccatatatca aagtagacaa tgatatattc tttgaagaac
     2161 agaaaaaaaa tatatcaaaa ggtattccat ttggatttaa tagtacttat aagaaaagtc
     2221 ttaaaagagc agagaataga aaagaggcta gaataaaaat agaaaattcc aaagcagata
     2281 tacttatgat tgctggaaaa gaagataaca tatggaatag ttatgaagct tgtttaaagg
     2341 cattagaaat ctttgaagaa aataattatc catataacgt agaattatta acatacaata
     2401 atatgggtca tccgttacca attccatata ttatgcctct aaaggagact ttatgtatga
     2461 gtatgagtgg agggattttt tcttcaggtg gaactgtaga aggaaattca aaaggacagt
     2521 ttgaatcatg gaatagaact attgaatttt ataaaaaacc tttatcaagt gatttaaata
     2581 actactatta agtgatttaa gtaactaaaa atgaagcggt ctttctatat atgcacaaaa
     2641 tctatcaatt ttatagattt aatttattgt ttatataatt tgcatgttat atactaattt
     2701 taatgacatt gataatttat aaacaattat aaagttgtaa acttataaga gttattgaaa
     2761 ggtggagtga agttatggaa agactcgcta gaagggaaca acctcatata aaatttggaa
     2821 tgtttaagat aagaattcca tttatacatt acagatttga gaaaccagaa gctattcaag
     2881 gtataatatc aagtatgaca agtttaggca caattggcct tagtacacaa attttgggat
     2941 taccctatga agtggcatgg agtatggcta tcattaactc aatattatac tgtttgcatg
     3001 tttttatggg agacccagtt gtacctggct ggattacagc ttctataact cttacaactg
     3061 catatttgtt aaagttcagc atgggcattg aaagaataca agcattaaca gctttacaaa
     3121 tagatttagg aataatattt attttaatgg gtataactgg tgtagctgga aagttagtta
     3181 gtaagatacc aaattctatt aaaggtggaa tactaatggg tgtcggtata tcgactataa
     3241 tatcagagtt taatcctaaa gggagatttg attcttatcc tatatctata acagtaggaa
     3301 ttttggttgc ttgttttgta atgttttctg aaagatttga tactctaaaa gttaagaata
     3361 aatttttatt tcatttagga gaatatggtg tagtatcagc tattttagtg agtttaatag
     3421 taggtatatt tagtaaagaa atagaaattc ctagatttag ttttgacaat ttagtttaca
     3481 tagtagattt taaaaatctg ataaatacag tatctccttt tggaataggt tttccaagtg
     3541 taatgttatt tatacaaggg ataccaatgg cttttatgat atacataatt gcctttggtg
     3601 attttataac aggtgaaaac ttagtacttt ctgaaagtga aaatagaaaa gatgaatata
     3661 tagatttcaa ttcaaatagg tctaatgtta taagtgggat aagaaatatt tttatggcaa
     3721 tcttttctcc atatatacca atgtgcggtc cattagctgc gacacttaca ggaagtgttg
     3781 ctcaaaggta caaggttgga aaggaagcca tgcagtctgt ttttagtggc atgggtacat
     3841 tagtatgggt ttcagcaatt tttatctgtt tttatccaat tgcgcagatt gctacacctc
     3901 ttataccatt agcattgtca gtaacacttt tagttcaagg atatttatgt acaaagctat
     3961 caatggagct atgtaataca ggtgttgaga agggattgat tggacttatg ggaggtgtaa
     4021 ttgctgctaa aggcggaaca tggggacttg ctgtaggttt tatactgtat ttcattttaa
     4081 ttgattctaa aaaaagaaaa gaaaaagata ttaattcaat agaagattgt gtatatgaaa
     4141 tattagacaa aaagaagagt atttaaagga aaatctgagt tgctgttatc tattaataga
     4201 ttaattgcaa ctcatgtttt atttataagt tttaggaatt gcaaaaaaat gcaaagcttt
     4261 ttcttgacat aatttcttga tatgttacta tagttatata acacatgtgt tttataaaaa
     4321 tttaatggag aggtgaacat atatgccacc taaagtaaag ataacaaaag aaatgatttt
     4381 gaatacagtc ttggatatta caagagaagt gggatttgaa gctgtaaatg cgaggagtat
     4441 tgcaagtaaa ttacagtgtt ccactcgacc aatttttact tgttatgaaa acatgaatga
     4501 attaaaaaat gaatttcttg cttttgcata tgaatattat aatcagtatg ttgttaatta
     4561 tcgtaattct aaaagtgtaa gcccttattt actgcttccg ctttcataca ttgaatttgc
     4621 tcaagaagaa acgtatttat ttaagttgtt atttataaat gatttagatt tgatgatgaa
     4681 agaggcgaat gatttttata aagaaattga caatgaaaaa aaggcaagac ttttttcgga
     4741 aagcattgga atagatttgg aatgtgcaaa agtaatattt ttagatttat ttctttatac
     4801 tcatggcata gctgtcttaa cagcaacaaa aaaattaaca ttagatagat atagtgctga
     4861 aaaaatgttg aaaaatatat taacagcttt tataagacaa gaaaaatcag attggaattt
     4921 gtctatttga tgtttattaa ctaatataga agaggtgaaa ttatggaaac aaaacaatac
     4981 ttaattgact tttataatac ttatgatgaa gatagtcgac ttgcattaaa acatggaatg
     5041 gtggaatttc tcactactat gcattacatt gataagtaca taaaatcagg tgattgtgtg
     5101 cttgaaattg gcgctgcaac tggtcgttat tctcacacac tggcacgtca gggatatgat
     5161 gttgacgcag tggaattagt cgaacataat atagaggttt tccataaaaa tactcaatca
     5221 aatgaaaata taagcattac tcagggtaat gctatggatt tatctgtttt cccagataat
     5281 aaatatgata ttacgttact gttaggacca ctatatcatc tttataacaa agaagataaa
     5341 caacaagctt tacatgaggc aattcgtgta acaaaacctg gtggtgtggt ttttgctgca
     5401 tatgttatat ctgatggctg tcttattgac gaggggttcc atagaggaaa tattaatgta
     5461 tctgaatata ttgaaaaagg tttgattgat ccacagacat ttgctgctaa gtctgaacca
     5521 aaggatttgt ttgagcttgt acgtaaagaa aacattgatg atttgatgtc tgcatttaat
     5581 gtaactagac tgcattatgt cgcatcagat ggtttggctt tgtatatgcg tgaagcagta
     5641 gactctatgg atgatgatgc atttgcatta tatttaaaat atcaccttgc tacttgtgaa
     5701 cgtgaagatt tagtaggggt tacaagtcat gcaattgaca tatttagaaa ataaggaata
     5761 tgcttgttta tgtctctggt gatgttgctc ggagatataa gtaagtgtat ctgtataaaa
     5821 taaaaacaag tatagggata gaaaattatg taaagtcaaa attttctatc cttttagctt
     5881 ttaaaaaatt atgttaaaac ttgtataaaa aatggctatt ttttatatac attcttactg
     5941 agaacgtaag cgttctgtaa gtgatttttt ttctatattt cttacaagta attcagtcac
     6001 taaaacttgt ataccaatta atacgaatga aaaaattaaa atagtaaata tagaaaattt
     6061 aaaattaata aagtctaatc taattacatc ttttataaaa gtgcaaagta gatttgaacc
     6121 aaaataacct agtatacttg aagtacatat agctttgata cttatgttta gaccttctct
     6181 ataaagcata tttcgcagtt gctttcttgt cattccaacg gcttgaagta atgcaaactc
     6241 tttttttcta attaaaacgc tgtttattag ggtattggtc atatttagta taccaaagca
     6301 agaaattaaa ccaacaaaaa tgtatgaagc tataattata tattgaaatg ctctagtaat
     6361 cattctataa tcatcttcat atgaataaag cattaaattt gaatttttct gaattatact
     6421 taacaacttt tcttcaactt ctttagaatg ctttttatct attaaaatag aaaaatctaa
     6481 atttgtatta tatggtgtta gagattctaa agttttgtct gaagcaaaaa acatacctcc
     6541 tgtattggaa ttgtcaatga ttcctataat tttcattttc tttttaataa tatcatttcc
     6601 actaaagata ttaaatgtaa ctgtatctcc aacttttaaa tttaatccat aatattttgt
     6661 tctatattta tttataatta aactatctga atctaaatgt gtatagtcta tttttccact
     6721 gacaatatat tcttcaagtg attttgaaag ttcaggcgta atacctttaa ttagagtaat
     6781 aaattgtttt tcgtctctat ctttgatgta aggttctata atattacttt taattgattt
     6841 ggattcaatt aattttttta ctccatgaat agatttaatt tcattcttaa gagaatctgt
     6901 tagtggatta ttttgttgga tttctgtaat atgctcatat aagttatcac tcttaatgct
     6961 aattatataa tcttcgttat agacaaattg ttgagatagt tgttttttga aatctattga
     7021 attagcaaga ttagcgattg aaataaataa aactccacta atgcttagcg atattaatgc
     7081 aatcaaattt ttctttctat ttgactcgat attctttaat gctagatttt ttatatttat
     7141 ataactaaaa ttttttgctt tttttctaaa tttagtttct gtatattgca tggcttcaat
     7201 agcagatatt ttagaaataa ttctagctgg tttaaataaa gaaattctaa cagttaaaaa
     7261 cattaccagt gataaaatta aaattataaa taaatcagct atcatttgcc atgctaatgg
     7321 ttgaattatg taagcaatta tacaagaagc tataacccct aatggaataa aaataattga
     7381 caaaatattt ccttgtagag aaataatttt ttttaactga aaagaagtca tacctaacga
     7441 tttcaactta gcatacatct gaactgaatt aacaactgaa atataaaaaa tactatatat
     7501 aacaaaaacg ctagaaaaaa gaacaactat tccaactact aaaactgtaa taatctgctc
     7561 accatcaatt aaatttgatt caatatagtt atcatttaag tatatattat atttcttaat
     7621 acctaaagat aaaccaattt tatttaactg tgtcttaatt gaagctgaat ctttctctgt
     7681 attttcttct gatagtttaa ctaatacatc tacagtatca ggtcttgact cgtcaaaagt
     7741 attactttta ttttgtaaag gtgtagaagc tatattctta aaataatcat ttgaaacgac
     7801 tgtatagtat tgcttggcat tatcttgata ataattttct agaaatccaa caataataaa
     7861 atcacattga acttctttat tcgtaatatc atcataataa tttaatttaa tgctatctcc
     7921 aatatcttta tctaaaccaa attcctgtaa atatttttct gaaatagcaa tttcattttt
     7981 atttgtaggt agtttgcctt tcaatggttg aaaattcata agtttaattg ctgtatcatc
     8041 tgcataaaca atcgacataa tacaatctgt ctttttatta cttccaatta atttgtaagt
     8101 tcctacgcca ctaaagtttt tatctttata tagtatattt tttgcttttt catctacaga
     8161 tttatatata gcatgatatg gagatgcatt aactaaatct acagaggcat tatatgaaac
     8221 taaggtcact gttaataata aacatgtaga aatcattata atgatacctg aaagatatgt
     8281 tttaagttta ttaattttta aatcatttaa agctattttt cttataaatg tgcgattatt
     8341 atttctaaac atatactaca cctcctagtt aacaattttt ccatcttcaa tacgaataat
     8401 tctatcagtt agttgtgcaa tttcattatt gtgtgtaatc attacaattg tttggttgaa
     8461 ttttttactt gtcactttaa gtaaactcag tacatctgaa ctagttctac tatcaaggtt
     8521 acctgttggt tcatcagcta gtataatagc tggttttgtt acaagtgctc tagctatagc
     8581 aacacgttgc tgttgaccac cagaaagatt acttggtata tcatataatt tttcttcaag
     8641 agaaagcata tttataattt catttataaa atccttatct atggtctctc catccaatcc
     8701 tattggtaag ataatatttt catatacatt aagtaaagga acaagattat aattttgaaa
     8761 tataaaacct atatttctgc gtctaaagat tgtaagctgt tcatcagaca tagtagataa
     8821 ttccttaccc tttataataa cctttccaga tgtaggatta tctaatcctc ccatcatatt
     8881 taataatgtg gatttgccac taccagatgt acctacaata gaaataaatt cgcctttttc
     8941 aatagataga gttacaccat caagagcttt tgtaatgttt gaactttgtc cataatattt
     9001 ctttaaatta attacttgta aaatactcat aataatacct ccttaacatc ttgtaaatac
     9061 agtataaaac caaaatgttg cagaatcatt acaaatgaaa tatttaaaaa tttatttatt
     9121 aggtaagaaa atagaaaaag tcgacccttt tccaatatct gatgtaactt taatatagcc
     9181 accttgaaga gatataattt ttcttgaaag atagagacct attccaatac cttctatgtc
     9241 atggacatct tcttcacgat aaaatctttt aaagatttct gcttggcgac tttctgatat
     9301 tccttttcca ttatcaataa tatctatttt tgtatacata acccaacatt ctgtagctac
     9361 acgtatctta ccattagaac ttgtgtattt tacagcatta tctaatatat taaaaatagc
     9421 ttcagaagtc catttcttgt catgaattat atataaattt gggtcacaat caactgtaac
     9481 ttcaatattc tttttttcag catcaaacaa aattccacta agtgctgtag caattgtttc
     9541 ataaattgaa tttttctttt tagatagtgt gattatacct gtctctagtc tggaggtttt
     9601 taccatagat tgcattaaaa aatctaattt atctaattgg ttttccatat ccattaaaaa
     9661 atccttttga atttctgttt taaatgtttg atttagtaga gtagtattaa tcatttttaa
     9721 atttgcaata ggagttttaa tttgatgaga tatatcagaa actagttctt gtaaatcagc
     9781 tttctctata gcaatactat tgcgattttc ttgaataact tcatacattc taattaatct
     9841 gtgattgata cgtgataaaa tagtttcttc ttctaattca atttcaatat tatcttcact
     9901 attcatcata ctatctaaag tgtgacatat tctagaacaa aatataacta tttttttatg
     9961 aagtaaaaat attattaatg ctataaatcc acaaagtact attgtatata ttaataatag
    10021 agcaattagt tttaaatcat cagttattag ataaattgag atactaaata aaatagctgt
    10081 aaaaattata ccaacagcaa ttattaaata aatagaacta aaagaaaatt ttttaaaatt
    10141 catttctttc acctaaccac atatatccca taccatatac cgttttgata tacttaagat
    10201 tgtctttttc aattttgctt ctaatcctac ttataacaga tgttaaagta tgttcatcta
    10261 caaagttagc atctatatcc cagagttttt ctaaaagtac tttccttgtt aaaatacttt
    10321 taggattttc agtaagcagt tttaaagtac gatattctaa tggtgtaaat ataatttgat
    10381 ttccatttat attggcagat aactcagaaa agttaatttc aagatatcca tccctatagt
    10441 aatcttgttt tgtttttatt gtaagatgat ttaaaaaagc tttaattttt tgtttaaata
    10501 tattgatatt aaatggtttt gttatataat ccaaagctcc aagttcatag cctttaatca
    10561 tatcacattc catatcatta gcagttaaaa aaattattgg tatattgtaa ttttccttta
    10621 tttcattaca taattcaaac ccacttttat ctggtaaatt aatatccaaa attattaaat
    10681 caaattcaca ttcaaaaata gactttagtg cagatttagc tgtaaatttt gaagtaatta
    10741 tatatccatc ttcaattagg ttatatgata gagttttatt taatatagaa tcatcttcta
    10801 ctactaatat tttttccata cagttactcc ttttagttta atattttata atgtcaatta
    10861 tagactaaaa acattgctga attgttataa acgagaaaaa gtatttaaaa atttatatat
    10921 ttaataaaga acctgtccta tgataaattc tagtacagat tctttattaa ataaaattat
    10981 ttcaaccaag atggatttcc aggtataaat attcttttac caaattttga agtatactca
    11041 tctaaagctt tttgaataag ctcattatta cccttaaatg aagtagtatt ctttatagtt
    11101 tcgagatttt ggctaaatgg gcaagcagat atacacatac cacaatctgt acctaaatat
    11161 ctccatttaa tatagcatgt ctcatgttca attacccaat tatattttcc atcatcacca
    11221 attttaatat cattagaaag cgaatgagaa gggcagttaa aagagcattt tttacagacc
    11281 ttacaaaaat cttctagtcc aaaatcaaca tattcatctt ctaaaagagg aatatctgta
    11341 gtaacaacac ctaatctaag tctagagcca taatctttat ttgtaagtat agcatttctt
    11401 cctatatctc ctaaaccagc atcacgagct ataaaaacag gcattactaa ataattagca
    11461 tccatatgat ttctagcatc atatcctaaa tttcttatat agtaacttaa aatcatgccg
    11521 acgatagatg catccacata gcactttgat gtttctataa cttcacatat cattggagct
    11581 ctatttatca tttctttatc catctcacat ccaaatacaa ttgcatactt atgagttaga
    11641 ttaatttctt caccgtaatt ttcttcatgt ctacccctat ttgtataaat atgatagtct
    11701 tttaatttag ttataccaac tacagaagct ccatactgct ttgcaagacc cttaattttt
    11761 tttgtcattg actttgcatc tacatctact ttagtatcag aaacttttcc ttcgcataaa
    11821 gatttgatat cagataaaaa atcgaatgca ctacttgcca ttggagagtt taactcattg
    11881 taagtcattg ttccttcact acataaattt ggtctatttc ttatactatc atcaatttct
    11941 tttttgtcag gatttttctt ataatagtca ttataagcag tactatcttt tttgtaattt
    12001 gctcttgcaa acatagtatt tctctcatca acccttttca attctattcc ccctagtaaa
    12061 aatatattta aaaaatataa ctttattgtt gtataattta attatataag aataaagtta
    12121 tattttcaat ttaagcgtaa ttaaattggg aaatatataa ctatatgctt gattataatg
    12181 tttttatttt gaaaacaaat ttaaatacaa tctttttagt gaaataaata aaattaaaat
    12241 atttttagta tgataatgca agaaaataat tatttatcta aaaaatctaa aggagagtaa
    12301 aattgaactt attaattatt gaagatgata taaacttaaa tgaaggtctt ttttatgcat
    12361 ttgagaatga tggatttaat gtatttaagg cttatacaaa acaagaagga ttaaatatat
    12421 ttaatagtaa aaatatagat tttataatct tagactgcaa tcttccagat ggagatggat
    12481 ttgatgtatg tcaaataata agggaaaagt cagatatacc aattataatg cttactgcaa
    12541 gagactcaga aattgatgaa gtaaaaggat tagaaatagg gcttgatgat tacattacaa
    12601 aaccattttc tttatctgta ttaaaggcaa gagtcaaagt agcaataaga aaaaaatcga
    12661 ataataaagt aatatattcc aatggaataa aattggacca aaagttacta aaagtatata
    12721 aaaataaaga atgtttggaa cttagctctg tagaatataa gcttctaagt tatctaattg
    12781 aaaataaagg tcaaatatta ttaaaggaac aaattttaca ccatatttgg gacagcgaag
    12841 aaaattatgt tgatgataat attgtatctg taaatataag aagacttaga gtaaaagtag
    12901 aggatgaccc atctaatcca aaatatataa aaacagctta tggaatgggt tatttatgga
    12961 atgaggtaga ataatatgtt tatattagcc tttataatat gtacagttgt tatatttata
    13021 gtatctacta aaataaatcg aaaaagatat gatgaattaa atttgatgtt aaatcaaata
    13081 ttggaaggta aagaagttac ttatccagat acaaaggata caagagcgtc aaaaatttct
    13141 caccaagtaa aaaaaattaa ggatatgata gaaatagagg tagaacagtc aaagtcagaa
    13201 aaagaagcga ttaaaggttt aatatcaaat atgtcacatc aattaaaaac tccactttca
    13261 aatataacca tttattgtga acttctggag aatataaata tttccacatt acagaagaag
    13321 gagtttttac aaaagatgaa aaatgaaact tttaagattg actggctgtt acaatcctta
    13381 tttaaaatga ctaaattaga ggatggagtt atagaatttg aagtagaaga actactaatt
    13441 aaagatactc ttattcaaag tatcagtact atctttaata aagcagaagc taaaaatata
    13501 aggataaatc tcgaaccatt ttcagacata aaattagttc ataataaaaa gtggaccata
    13561 gaagcaattg taaatgtttt agaaaatgca ataaaatact caccatcaga tagcacgatt
    13621 actatttctg taataaaaat ggaactatat acgaagatta ctattaaaga tgagggaata
    13681 ggtattgata gtagagaact aaatgatatt tttaaaagat tttacagaag taaaaatgtt
    13741 gaaaaccaaa atggcacagg gattggtcta tatcttacaa gattaatttt agaaaaagaa
    13801 aatggaaaca ttatagtaga atctaaacta ggaagtggat gttgttttag tatcttctta
    13861 cagaattgta agagtttaaa ctaattttgt aggatgagtg taattatcgt cacttacaat
    13921 attttataga acatatatct gtattgaaag gagaaattaa atgagtatat tagtgacgaa
    13981 taatttagta aaacactatg gaaaaggtga gactaaagta aaagccttaa atggagtaag
    14041 tatagaaatt gaacgagata catttactgc tatagttgga acttctggtt ctggaaaaag
    14101 cacattgtta aatattatag gtggattaga taatccaacc tcaggtgatg taataattaa
    14161 aggaaagaac atatctaaaa taggaaaaaa agatttgaca gtgtttagaa gaagaaatat
    14221 aggatttata tttcaaaact acagtttaat gcccgtatta aacacttatg ataatatagc
    14281 tcttcctgtt acattagata aaggaaacca tatagaccat gaatatattg aaatgctgat
    14341 gaagacattg ggaatttggg ataagcgttt aaaatttcca agcgaactat ctggtggtca
    14401 acaacagagg gtagcaattg ctagagcttt ggcaaataaa cctgcgctta tattagcaga
    14461 tgaaccaaca ggaaatctcg atagtaaaac tacaatggaa gtggtatgtt tattaaaaga
    14521 aagtagtgca aaattccatc aaacgatact tatggtaaca cacaatgaaa atatagcaca
    14581 agtatgcgac tcaattatcc atattgaaga tggagttgtg gtgaatactg gtggtgaagt
    14641 actatgatgt ctctagtaaa attttcaatt caatatataa agcattataa aaaacaatct
    14701 atatctatag ttttaagtat agtactatca gtagcattat tgacgggaat tggttcttta
    14761 gttcatagtg cagacaaaag tagaattgaa aagataaggg aagatagtgg agattatcat
    14821 tatttctata aagtagataa ggaacaactt aataaaatta aaaaaaataa aaaatcaaag
    14881 gaatacactg tagatagact tggcgttaca aaacctaaaa atcagataga tgaacctttt
    14941 attatagaat ttttaaatgc tgattcttca tatttagaca tgacaggtag aaaattatta
    15001 aaaggaactc ttcctagtaa agatggagag atagtacttg acacatattc tctaaacaat
    15061 ttaaatgtaa acaaagaaat tggaacagaa atcaatttag atggtaaaat ctataagtta
    15121 tgtggtattt tatcaagtct ttcaaaccca gaaactgctc tggagggatt tgtaaacgat
    15181 tattttcagc ctaaagaaaa ggattcttat atagtttatg taaaatatga tgaaaataaa
    15241 aatattaaaa agcaaaatta taaatttatg aaaaaattca acatatcaaa agaaaaaact
    15301 tatataaact ggcctctttc agttgaattt ggagtaaaac caccaaaaaa tatagaaaaa
    15361 tataatatat ttgagttctt aaaaaattta gaactaaata caaatgcaat tatattactt
    15421 gttggagtgt ttggtgcagc agcagtatat agtattttcc atgtttcaat acttcagaga
    15481 atatcacaat atggggtttt agaagtatta ggcgctaata ataaacaact tttatttcta
    15541 ctatttttag agttattttt actttttatt gttggatttc ctataggttg cttcttaggt
    15601 attgaagtgg cgtctacaat atatgaacaa tttccacata tatttttgag tagtgatatt
    15661 gttccaggag cattttttat aagtgaaaaa tctatttatt taggcttttt atttatctta
    15721 ttgttgttaa ttttaattgc tgtacgtgtt gtacatcagt tgaataaata ctctagtata
    15781 gaatctatga aaaactttaa gattactaat aagaaaaaga gaatattaga aagtgtaaaa
    15841 cactctaaca tgacaaaagt attatctcat aaatacatga ctcaaaaaaa gggaatgttt
    15901 attggaattt tgttttcatt atcacttggt ggaattatat ttttatgttc tagttactct
    15961 atacagctta ctaaaaataa taatgaactt acaatgaaag ctgatgatgg tttaaattct
    16021 gactaccaaa taactatgca aacaacagat tttgatgtag gtataccaaa agataaaatt
    16081 tcaagattaa acaatgttga gggaatatca aaagtctatc cagtaagata tttatttgga
    16141 gctatgcaaa ttaaagaaga acaactattt tggaaaaatt tctttaaacc tcttgaaaaa
    16201 gattacagga taaagacttt ttttgatggt atttgtacaa agcaaaatga aggtggctat
    16261 cttttaaaaa caaatattta tggttataac aatggtatgt tagaaggatt aaattcttat
    16321 attatagatg gggagattaa tacccatgat atggttaaaa ataataaggt tatagttaga
    16381 ctacctatgg atggaactgg gatgtatgat gcagttgata taaatccagg agatacaata
    16441 aaagttaaag tgccaaagac aatgaaacca acagatgaaa ttgttaaatt taaagaagaa
    16501 aataagaatg attatacaac aaaagaattt gtagttgctg ctactgtaaa acgtgtgatg
    16561 gcaaataaca tatatttcat tggtgattat ggtatggata tagttatgac gaatgggcaa
    16621 atgaaaaata actttgatat cgaaaattat aattcagtaa gtataaaaaa gacagaagat
    16681 agtaacagtg aggaattgtc tgagaacata aaaagtgttg taagtgatgt aaaaagatgt
    16741 atcgtaacag attataccat tgctattgaa aaaaataata cctacttaaa tcaaaaactc
    16801 ttatttatat atggtattgt atttgtactt cttgcaataa gtttgttcca tataatcaat
    16861 acagtaagct acttaatttt ttcaagaaga catgagtttg gaattttaag agctatgggt
    16921 attacggata ataagttttt acttatgatg ataagagaag gttttttata tggattctat
    16981 gcaagtatta taatggtaat tggaagtgtt attggacaat ttatgattta ttttatggta
    17041 aaacgtgtat atttatatat aaatccaatt cttaaaataa atacacctct atacataggt
    17101 atgattattt taaatatcac tattagtata gttgctgtaa ttattccagt aagacaaatt
    17161 ttgaagagtg atattatttc agaaataaat aagaattaga gttatataaa tttttaagat
    17221 tatataactt tctgacaatc ttgtttaaat tatttaaata tatcttatct gtgaacatta
    17281 aataaacctc ttaatagata taactcttga aaagtcatat ctattaagag gttttaataa
    17341 attttcatgt taatatatat aatccaaaaa aattaaatct tattaaaaca tactattttg
    17401 tatagttatc gaaatatcct tgtatgtaaa taataggagt acccttatct ccacttccag
    17461 atgttaaatc tgctaaagaa cctataaggt ctgttaatct tcttggagta gtaccttgag
    17521 aaaccatgtt tcctgttaaa tcatcagatt tattatcttt ttcaactatg tattttgaaa
    17581 ttgcttcttt taactcatca ccagataagt cagcaaaatc attatctgct aagtatttta
    17641 attttacttc gtttggagtt ccctctagcc cttttgtata agcaggagat actactgggt
    17701 cagctaattc ccatatttta cctacagggt ctttaaaagc tccatctcca taaaccatta
    17761 cttctacatc tttccctgtt atttctttta tattaccttg gattttgttt acaacttcat
    17821 cacaatttat agggaataat tttactgttt cttctgtagc tttgtttgaa cctaaaagtc
    17881 catactggtc attgtaacca ctaccatcta cacttgctgt cattatatca tcaagtgaat
    17941 atactttttt agctccattt tgtcttaaaa ttctctttgt tctttgtctt gtatgtatat
    18001 cacaagttaa aatacttgtt gtatagttaa gaatagtttt tggattgttt gcaaatacta
    18061 tttctacctc tgcaccacaa tccttgatta aattcttata ataatcaaca taatctacac
    18121 cagtaaatgt atgcttgtta tatccaaata gttctctgta tttttcttct gttaaaacat
    18181 ctgaccaagg atttattccc ttatcatcaa gttcatcaat acttattaag tgatttccaa
    18241 cttcatcaga agggtagctt aacattaata cgacttttct acatcctttt gcaattcctt
    18301 ttaaacatat agcaaaacga tttctactta aaattgggaa tataactcca acagtatcat
    18361 ctccaaattt atcttttaca tcttttgcaa tattgtcaac gtgagcataa tttccctgtg
    18421 ctctagctac aacagcttct gtaacggcaa ttacatcttt gtccctaact tcaaagtttt
    18481 cactttttga cgcatttaaa acagaatcaa caactatttt aactaagtca tctccttgtc
    18541 ttataatagg tgctctaacc cctcttgaaa cagttccaac taatctatcc attatctaaa
    18601 atcctcctaa agaattaata ttgtcatatt agtaccatgt atattataat tcaaatataa
    18661 ttataagtaa aataaataat actaatattt gacataagga gtaattatat atgaatataa
    18721 aacttgaact ttataaggtt tttaatgcag ttgtaaataa taagagtttt tctcttgctg
    18781 ctaaggaatt gtttatgtca cagccagctg taagccagtc aataaagcaa ttagaagaac
    18841 aattagatac tttattattt tatagaaaca ataaaggagt aaaattaact ccagagggga
    18901 aaattctaag tgaacatgtc actactgcat taaagttaat atcatcagga gaagatagaa
    18961 taaataaatt taaaaaatta gaatacggtt ctctgaaaat aggagtagga gatacagctg
    19021 cacgtttttt cttgttaaaa tatttagaaa tttttcataa gaagtatcca catatacatg
    19081 tatctacaat aaatagaacg agtagagaac ttatatcttt actcaaagat gggaatatag
    19141 atatagcaat tataaacatg ccaatagaag atgatacact aaatattgtt gagtgtattg
    19201 aaatacatga tatatttgta tgtgcaaatg attacataga atacaaaggt aggaaaatat
    19261 cattggaaga attaaacaca ttgcctttaa taatgctaga aaataaagca aattcaagac
    19321 tttatgtaaa tgaatatttt ttatcaaaag gtataaaact aaacccagat atagaattgg
    19381 gttctcatga attactttta gaatttgcgt atataaatct tggagtgtct tgtgttatag
    19441 aagaatttag catagattat ttggaaaatg agaaattgtt taaattagat ataaaagagc
    19501 caatacctaa gagaaatata ggttattgcc atttaaaaga tatatcttta tccttagcaa
    19561 ccaaagaatt tttaagcatg atatctaata atatataatt tagaatacat atttcacaag
    19621 taatttaata taaaaataga gataaattcg taaatttgaa agattcatat agtaattagt
    19681 ttttattaaa aataaaaata aggttaattt gagaacattt atataattaa tatcgtattt
    19741 taaatatgaa cagtatattt agattaatgt ataaaggggg attagaaatg tctgattctg
    19801 aatatcctca aatgaaaacc ttagaaacta gaagttgtat actaagacct gcatcattag
    19861 atgatgttga agattttttt gactgttata aaaataaaat agtagtaaaa catttaccat
    19921 ttagtgagca taaatcttta gaagatacaa gaaagtttat aaaatcattt tttctaaatc
    19981 catataaaaa agggaaaatt ggccactttg ctatagtata taaaagagac aataaagtta
    20041 ttgggaatat ggggtttaat aatataaatc ctaaagcatt agaagcagaa ataggtatat
    20101 gtataaatcc aagctattgg ggacatgatt ttgctactga gataacaaaa agagtaatac
    20161 agtatggatt tagggaacta aacttaaata aaataattgc aataacctat gaagaaaacc
    20221 aaaattctac aaaatcatta gatttattag gatttaaatg tacaggaaag tatatcaaaa
    20281 aaattcatac tggaaatact gtaaaaaatg ttccttgtta tcaatatgaa ttgaaaaaac
    20341 aatagatata atcatttaat atctatgctg gttatttagt aatgattgtt ttctaaataa
    20401 aatttcaata aagtggttgc ctcaaaatat agataatcct gtttttattg ttaaaatact
    20461 gaaaatgcat ttgattttat acaaaaaaga gtgtctcatg aactaaaaag tttatgagac
    20521 actctttttg aataaatcgt attttaatta aaatagtata tatacttaaa atattaattt
    20581 ttattagttc tctaaatttt taaatccttc tccaagaacc tcatgtacat ctgtaacaat
    20641 aacaaatgca gtagggtcag ttcttttaac taatctcttt agataaagtt cttgtttttt
    20701 agaaactacg actaatagaa cttctttatt ttctctagtg tatccacctt taccatcaag
    20761 aatagtaaga cctctatcaa gttcttcagt tatagcttgt cttaaacttt caggctcatc
    20821 agagataata aaaaatgctt ttgaatggtc aaatccttcc attatcatat ctgctatttt
    20881 tattaataca caaagtgcta taccagagta aagagcagtt tctaaactac gatttactat
    20941 accagaagat ataacaacca ttccatctag gcatgacatg aattttgtag cttttattcc
    21001 tgggaatttc ttactaagta tgagtgcaat taagtctgtt cctccagtag aagcatctga
    21061 tttaaacatt attcctaaac ctataccaac taggattcct cctgcaatag aagacaataa
    21121 taagtcatta gtaaatctta gttttgataa tgggtctgtt aattgaacta tagctgaaaa
    21181 tacaactgtt ccaaataaag tttttaatga attttttgta cccataattc taaaagcaag
    21241 tattactaat gggacaccta taattaacat gatagctgat actggaagtc ctgtaacctt
    21301 gtttagtact aatgatagac cactaagtcc tccaggagca attgtatgtg gttttaaaaa
    21361 catatttata ccaatactca ttgatataca accaaaaaat agtccaagca tttcaagtaa
    21421 aattggcgac ttttgttttt tcatataaac acctccatga acttgtcaca atttaatatt
    21481 ataacatatt tgaccagttt atattatata aaatttcttg atataagcaa tttcaagtat
    21541 ttcattattc ttaatatttt tgaattttta tatagtgttt tcatatcttt actgatgttg
    21601 ttacactcct atgaagtttt ttatatatta taattttttt attcttttat aaagtatccc
    21661 ctataaagat ggttctatga aaattttctc tatattgttt aacgtatata gagattttgt
    21721 gtataattat aaggtattta atggaaaaat ttatcttact tttatatgtt atcaaaatga
    21781 tttattaaat acaacagaca gcttgataac atgtaattat ataaatataa tttatgtaga
    21841 tagttgtatt tttaaataaa tttttacata tcaataatta ttgtctattt tatataagca
    21901 acaatcaaac taaaataaaa gtttaagaaa agagttgatt aaatgcataa acctagttat
    21961 aaaacagtat ttcattcata cattattttt ttcatgattt ttatttgctt aatcctgaca
    22021 gtaataggta ttttcttatc acttattact attcagaaac caaatgggga atttattcgt
    22081 agtgactggc cgaaaaaatt tacagaaaac tttaatgaac aaatcgtatt tatagataat
    22141 aagccacaag taaaacagtc tggattagaa aaacttcgag aaaatcaatt gtggttgcaa
    22201 attttagatt ctagtggaaa tagagtttat gggtttttag aaccaaaaga gcataaagat
    22261 tattattcta attctgaatt attagcatta gctaaccaaa ataattcaag taatggaact
    22321 gtatacttta atacaattaa aaataataaa aatgactata tttatattat atattttcca
    22381 ttaaatatat ctaaagtgaa tatgtttttt gatggaggta aatttatagg tggtaagtca
    22441 attgtatttt caatcatagg gattatattt ttaataattt tggtttctgg aattgcttat
    22501 ggttactggg taacaaagtg catatcaaat attacatctg ctgttagtga tatttcaaaa
    22561 cgaagctatc ttccagttaa tattaaaggt gtttttgctg atatatataa tagtttaaat
    22621 attttaaatg aagaaattca taaaagtgat gagatacaaa ataaaactga tattatgaga
    22681 gaagagtgga tttcaaatat aactcatgat ttaaaaactc cactttcacc aataaaaggg
    22741 tatgcagagc ttcttacaga tagtagtact aattattcac ctgaaaaagt atataaatat
    22801 gcttcaatca tgttaaagaa catagaatat acaaatacac ttataaacga tttaaaatta
    22861 acctatcaat taaaaaatgg aataatccct ttaaataaaa ataattatga tttagtaaga
    22921 ttcttgaaag aattatccat tgatatttta aattatccag aatatgaatc aaatatagtt
    22981 gaatttaaga gtaatataga taatattaac tttgattttg attgtacact attaaaacga
    23041 gcttttagta atcttattgt caatgctttt acatatggag ataaaaatac taaagtttgt
    23101 gtacatgtaa cattaaatga aagaattgaa atcattatat ctgataatgg aaaagggatg
    23161 tcaagagaag aagcatcaaa tttgtttaat cgttattata gaggaagcaa tacaaaacaa
    23221 aaaatagaag gaactggttt aggactagca ataacgaagc aaattattga agttcatgga
    23281 gggaatatat ctgttgaaag tatacctgga ttaggtagct cattttatat cacctttcct
    23341 atttaattaa ggttaattaa ggttaaataa aaaatatatt aaggttgata gattattata
    23401 tttatatagt agtttatcaa tcttttttat ttaaggggtg atttgattaa aaatattata
    23461 aatagaatga taaaagtatg gaggagtcta ttagagattt aatttagatt aaagtataaa
    23521 aatattagat tgaaatatct tagataaggg aagaaggtgt aagtttgaaa attatattaa
    23581 agtatatttt cacaaatatt aaagaacgaa aaattagaac agcagttatg ttattgtcca
    23641 tagttttatc aacagtttta ctttttgttt cattctcaat tggattatct tatgaaagtg
    23701 cacaaagaaa aatggcaaaa ggtatgtatg gtacagcgac tatatctgtc caaagtaaaa
    23761 atccagatat attaaccaat ttagaagaca tacctgattt aaatactata aaatcaaagg
    23821 ttggtgtatt ggaaagctct gctatttata ataaaggggg atactatgaa gaatttagtc
    23881 ttatatcagc agacttaagt caactaaata aaatcaacaa gccacgatta gaaaatggcg
    23941 atagtattac tgatttttct ggtgataaaa ttattcttcc aaatcgcttt acatcaaaat
    24001 ataaaataaa aaaaggtgat tctattactt tgcagattta tggaaagtct tatacttttc
    24061 aagttagtga tattgcatct tatgatacag tatttttgag gaacacaaga ggtgtaaatg
    24121 cactgctacc caaagagact ctatcaaaaa ttataaataa aggcagtgga tatacaagag
    24181 ttcttataga gtcagaagaa gaaattacag aaaatctagt aaataaatta tccgaagaac
    24241 tttctactga aaaatatatg gtatcaaata ctataaatga aactaagata atttcagatg
    24301 ctagacaaaa gacaatgcct ttctttttaa taagtttttt tgcattaacc cttagtatat
    24361 ttataatata cagcagttat aaggttatta cattagaacg tcttcctttt attggaacat
    24421 ttagaagtat tggtgccaat gaaaaaactg taactcgtat attgatgctt gaaagtatat
    24481 tatacggaag tataggagga ttaattgcta ttcctattgg tgtagttgtt ttaaatttaa
    24541 tgcttcatgg gttaggaaat tctctcgaac aaggaatatc aattccagta gtaatatcac
    24601 ccattggagt gattatatct gttatagtag caataatcgt ttcttcattt agtgcatata
    24661 tacctgttaa aaaagctagc catttgccga taaaaaatat tgtactagga acagtagaag
    24721 aaaagaatgt ttcaaatcgt tctatacttt ttataggaag tataatgttt attttatcta
    24781 ttttacttcc aagaatatcc cctgaaaata cattgtatct agctggtgga ttttcattac
    24841 taggattaat tgtagctact attgtgttga ttcctcttat tactgatatc atgtctatag
    24901 tttttgagtt tgtttataaa aatattttag ggaatgaggg taaattagct gctagaaata
    24961 tgaaaaataa caaaaatata atacagaata tcactttact atttataagt atttctgcag
    25021 ttattgcaat aagtgttgtt ggtaactttg tcaaaactta tataacagat gtgtttcgtg
    25081 acgcagaatt acaaggtttt gcagatggaa atatgaatga agagtttatt gaagatgtta
    25141 gacatatgga aggaattaaa aaaatattac ctctttatgt tatgaataat gagatttctg
    25201 gtaatggtgt aacattatca agactagagg gtacagataa tataaaacta tataactcta
    25261 tgtttggaat caattataca aattttgaga taaaaaaaca agtaatagaa gcttttaatg
    25321 ataaacgttc tgttattttg aatgaagata ctctaaaaaa agtaggctta tctataggag
    25381 atacaataac tctatctaat gataagtatg atttttctta taaaatagta ggtagtttta
    25441 aatcccgtgc aaatgatgta gaagctgtta taccatcaca ttatgcagtt aatgattttg
    25501 ataaaactaa ttatggtttt ttagtatata cagcagtcaa tccagatgct gttatgattc
    25561 agataagata tttatttgga gatacatata attggagtcg tacagttgaa gaatttaata
    25621 atgattcttt aaatactata agtagttttt tgtctcctat gaataagatg acctatttca
    25681 tttttcttct tgctacagta ggtattatta ataatctact gattaattat attcaaaaaa
    25741 gacgttctat agctatgtat aaatctatag gactaagtaa taaacaaaat ataaaagtaa
    25801 cattgattga aggggttact tcaggtttac ttggagctgt tattggtatt gtgatatcta
    25861 tacttgagat tcaaactatc tttatagttg caggaccaaa aatttcaatg aaaccagatt
    25921 tagattttaa aacatttatt attgttgggt tattgggaat tatagtaact ttaataggtt
    25981 cgatagtgcc tattataaaa gggaagaaaa tgaaactgat agaagaaatt aagtttgaat
    26041 aattatggag gttaatatga aaattacaca taatagttta gctgtagaag caaaaaatat
    26101 tatcaaagaa tataaaattg gaaatacaac aactcgagtg ttaaaagagg tatctttaca
    26161 agtaatgaaa ggtgaatttg tttctatcat gggtcaatct ggttctggta aaagtactct
    26221 tttatatatt ttaggtggtt tagatactcc aacgagcgga aaagtgtata tgaatggagc
    26281 tgatatatca cattttaatg atgagaaaat gagcataata cgtcgtagaa atataggatt
    26341 cgtatttcaa ttttataact taataccaaa tttaaatgtg gaggaaaata taatgcttcc
    26401 tttgttatta gatggtaaaa atttaaaaga ttataaaaat caattagatg aaatcttaga
    26461 tatagttggt ttaactgata gacgtaaaca tacaccacga gagttatctg gtggtcagca
    26521 acaacgtgtt gctatagctc gagctttaat tggaaaacca gagattctat ttgctgatga
    26581 gcctactgga aatttagata gtaaaacagg gatagaaata atagatttac tgaataaaat
    26641 aaacagagac aatggacaaa ctataattat ggtaactcac tcaccagaag cagccaaaag
    26701 tagtagtcgt actattacag tttcagatgg tttaattgta taaggactaa ttattgtatt
    26761 tgagataagc atttttaatt atataaatta gacatatgta aagtggatat aagttaaata
    26821 ctataaatgt gctataatat taaaataaca gataaaagta ctatattttt tattgattat
    26881 tttaatttta tttgtttatt aaatatctaa tgagtattca tactatctct attattaaaa
    26941 gcagttaatg atatatagag ataatatgga ttcttcttac tttaataaat attcacgata
    27001 ggacaggata taatatatgt taaaaaaaga aagtattcat tttataaata aaaataggtc
    27061 acttatagtt tgtgaagaca attttgttta tctcttgcct tgtatacaat taagaaattg
    27121 gatatcgaat tttactatat cgtttccaaa tcaaacaata atttctgata attacacgat
    27181 tattcctcat ggaagtgtaa ctttggtgtt tttttatgat gccacagggt tacatagtct
    27241 attatttggt ccaactacta aaccaaaaac agtaggaaat attgctaata gatgtgatgt
    27301 tatactaatt atagaatttc aacctgctgg ttttttcccg cttataggta tacagcaaag
    27361 tgaacttatt gataaagttg ttccattttc tataattaat acttcattag atttagaaat
    27421 taaaaaaata tttaatgaat ctttatctat agataaattg attttaaagt tggaagaatt
    27481 attgatttct aatattaaaa ttgaatactc atatgagttt attttggcaa ttcagttgat
    27541 tattcaaaac tctggaaata tatcttcaca agaaatttct aaaaaagtat tttatagttc
    27601 taggcattta aacagactct ttaatcagta tctagggttg agtatgaagt cattttctcg
    27661 tttggtacgt attaataaat ctataaaact tctaaacaat aataaaactt catggatgtc
    27721 tatatgtaat gaattaggat tctatgatat accacatttt attaaagatt ttaaaattgt
    27781 ctgtggaata actcctcaaa aataccgagc taatatgtct gatttttaca gtgaaattgc
    27841 aaaattttaa gttataatac ttataacaaa gaaaggatag tgataagatg aaatttggag
    27901 gagtattgct aattgtcaaa gacataaata aatcaaaaaa gttttttgaa gatgttatgg
    27961 agcaaaaaat cacattagat ttaggagaac atgtatcatt tgaaaatgga tttggattac
    28021 aaagtaatta taaagctata attggatatg atttaccaat atatcaacaa tcaaataact
    28081 ttcagttgta ttttgaggtt aatgacatca aacaatggga aagtaagata aatagaatag
    28141 gaaatattga atttttgcat tatataaaag aatacccatg gggtcaaaga acttttaggt
    28201 tttatgattt tgataaaaat attatagaaa tttcagaaag tatggaaagc gtcataaaga
    28261 ggcttttaaa acaaggttta gctttagaag aaatttcaaa acgcactatg tatccagttg
    28321 aatttattac acaatttcaa caagtataaa atattaaaat atataatttt ttctttatat
    28381 tgcaaaaaac aaaggcttgg ggcataatag aaccagaaaa acctgaatct caacagcaaa
    28441 tggctcatat ggatttcgct gttaaggatt tagaagaagc agttcaatat gcaattcatt
    28501 gtggagctac aatcgcagag gagcaattta ctgatgactg gagagttatg attgacccag
    28561 ctggacaccc tttttgctta tgtcagatga aatcaattat ggaaagtagc catttttcat
    28621 tgttatagac caaaatattg tttattaatt acaaaaaagc acaacagtat ataccgttgt
    28681 gcttttactt attatacatg aatacactaa aaaatataaa tagtagagct ttatcaataa
    28741 tgataatttt taaaaaatag tattttttta ttgaataatt tcttagatat t
//
LOCUS       DAYAOO010000049        28629 bp    DNA     linear   BCT 12-OCT-2024
DEFINITION  TPA_asm: Clostridioides difficile isolate ST8-SSI-h139-18
            SAMN40601845-rid21577343.denovo.049, whole genome shotgun sequence.
ACCESSION   DAYAOO010000049 DAYAOO010000000
VERSION     DAYAOO010000049.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN40601845
            Sequence Read Archive: SRR28438827
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 28629)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 28629)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-MAY-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-MAY-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002157583.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002157583.1
            Genome Coverage       :: 163x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/11/2024 16:19:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 4,038
            CDSs (total)                      :: 3,963
            Genes (coding)                    :: 3,930
            CDSs (with protein)               :: 3,930
            Genes (RNA)                       :: 75
            rRNAs                             :: 6, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 60
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 33
            CDSs (without protein)            :: 33
            Pseudo Genes (ambiguous residues) :: 0 of 33
            Pseudo Genes (frameshifted)       :: 7 of 33
            Pseudo Genes (incomplete)         :: 25 of 33
            Pseudo Genes (internal stop)      :: 11 of 33
            Pseudo Genes (multiple problems)  :: 8 of 33
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..28629
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN40601845-rid21577343.denovo.049"
                     /isolate="ST8-SSI-h139-18"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Denmark"
                     /collection_date="2018"
                     /collected_by="Statens Serum Institute"
     gene            595..2829
                     /locus_tag="ACGI5H_002362"
     CDS             595..2829
                     /locus_tag="ACGI5H_002362"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902499.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EAL domain-containing protein"
                     /protein_id="HFG9698063.1"
                     /translation="MQNHNYIKMLNKKVEVLSKELDSRNFKLKTLNEIDFFSKIPNRE
                     FMYQHIDDCISKNIHIGIMLLNIDNFKLFNDIYGYLVGENLLITLTQNLLHFIPESKG
                     IVAYLKGEGFLIVLPNVSNKELNNMGATIIESARELKIRLPNEKEIYSNVTFSIGSTI
                     WNGEPNMTTLMLFNQVYSALKKAKSEGKNRYILFDFKDNSFYNKLENDKEFLSEISHV
                     LQTKQIEVFYQPLYNIKNNTIVGCEALARWRHPIKGLLTPDKFIPLFEQFGLITELDL
                     HLFEENCKNIRRWIDNNDVFVPICCNFSRLHFFNPNFPSMLKGITEKYSVSTSNFSIE
                     ITENILIENTNTIIQQLAELRSYGFSVSMDDFGSGYSSFGMLQNLPFDIIKIDRIFLS
                     HNLNDFKNTTILYSIINIARALGMLTVCEGVETEQHVEFIKSINCDIAQGYYYAKPME
                     CKEFEKLLSKENNSEKMFIKYSDIGKSLIEKIFDGFFIMQDMKKLRANVTEDIQWFDF
                     YNKTEITSFPKVIEHFEKHIKGKKFSILYKSITPHNTESDSLLISGEAVLSDEASEHQ
                     KYSNFYFSANCIISENKLLLAKLHLDLIKTAGYINEFESYSIPKMTNTHLDESNILSQ
                     FYSMLPVGIIRYDLFGDMIITYMNEEMFDIIGYTKEQFFGEMGGNLRAIVHPDDLDFV
                     YKKSLDMIDTNKIEPFLYRFIKRDGQIVTVMYTQCNLSAIDGRSIAQGMYVDVNKIKN
                     LTKI"
     gene            2860..3705
                     /gene="dccA"
                     /locus_tag="ACGI5H_002363"
     CDS             2860..3705
                     /gene="dccA"
                     /locus_tag="ACGI5H_002363"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="c-di-GMP diguanylate cyclase DccA"
                     /protein_id="HFG9698064.1"
                     /translation="MFKEIFLRTFPGFLIIRDSNYRIIFINDNLKNLIKSYMQDNPLG
                     MTNIEIAKKLPDNIAKFFTDSHNIQLDWEKNYPYDKISNWILEFKKDTTSYWNVLEYK
                     VDVDEKTYIITMANDITKLYEENKRNLHYSITDPLTGAYNRKYLNDRFDIFIGDYIVL
                     IDLDNFKMINDYEGHNVGDKILCDFVSLLNKELINSTSIIRLGGDEFIVIFSSDVDKN
                     YVYSQLEALRENFLKVFSKYKYLSFSYGVDTVKRNLKLTIVELDKKMYKNKEKNKKKF
                     DKNDY"
     gene            3945..5678
                     /locus_tag="ACGI5H_002364"
     CDS             3945..5678
                     /locus_tag="ACGI5H_002364"
                     /EC_number="2.7.7.65"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429367.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0009975 - cyclase activity [Evidence IEA];
                     GO_process: GO:0009966 - regulation of signal transduction
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="diguanylate cyclase"
                     /protein_id="HFG9698065.1"
                     /translation="MSILLKKAPKLAKHIITSFYINRDINEVLKYLCENVTWIGPGEQ
                     EFLTSFNEIKNYFYAGQDEIPSCDINNDIFETVSEDENRCMVLGRYTVRTKENAQMIL
                     EVNQRCTFEIIEDRGKLLIKHMHISNPYGEMQLDEYFPTKIGTQSYDYLQRLLKEKTE
                     VIEMITNNINGGLKGSNDDSTYSFFYVNEGLPKILGYTYDEFMEMSGGSAVGAVYPPD
                     LPKALEDCERCFAKGPTYSSEYRIRKKDGTLMWVLDSGMKSLNSDGIVKINSIITDIT
                     QLKNIESELKLERERYRIALQNITDIMFEYDIENDTLIKYQRVEIDKKIELENFETKN
                     YSKLLESGKIIHLDDIGKLLEVLHGNLRETIEIRQVNSLTKNEWRWIRVQCSVIYDSD
                     HNPIKTIGVLKDITEDKSKLESLINQAQRDPLTQLYNQRVSQNLIEEYLCSSDSKNND
                     ALLVIDIDDFKTVNDTFGHLEGNEVLVAVSKILLHNTHDKDIVARIGGDEFTIFIKSL
                     TKDLIIKITNDILNDASKIKVKDNHKITLSIGIAFTDDSTKLYKDLFSKADKALYLSK
                     ADGKNCYSTYE"
     repeat_region   6010..6490
                     /inference="COORDINATES: alignment:crt:1.2"
                     /inference="COORDINATES: alignment:pilercr:v1.02"
                     /rpt_family="CRISPR"
                     /rpt_type=direct
                     /rpt_unit_range=6076..6098
                     /rpt_unit_seq="ataccacttagttaatataaaac"
     gene            complement(7020..7124)
                     /locus_tag="ACGI5H_002365"
     CDS             complement(7020..7124)
                     /locus_tag="ACGI5H_002365"
                     /inference="COORDINATES: protein motif:HMM:NF024729.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0015074 - DNA integration [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
                     /protein_id="HFG9698066.1"
                     /translation="MDDYIYYYNNFRYQNRLNSMSPFEFRKYLSTERA"
     gene            7749..7994
                     /locus_tag="ACGI5H_002366"
     CDS             7749..7994
                     /locus_tag="ACGI5H_002366"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438567.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9698067.1"
                     /translation="MNQKKIKISIKMVIIGIFSVIIAFVLSRLFVEYIDELLRSNWQY
                     QLFESESSYIIFANCIMFSNILLEIFLIYICRKFRKI"
     gene            complement(8747..8893)
                     /locus_tag="ACGI5H_002367"
     CDS             complement(8747..8893)
                     /locus_tag="ACGI5H_002367"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896328.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9698068.1"
                     /translation="MVFETFDKTIELYPNAKPIFHSDIGFRLDDESFEEYLGRVFRKR
                     CKGI"
     gene            8989..9312
                     /locus_tag="ACGI5H_002368"
     CDS             8989..9312
                     /locus_tag="ACGI5H_002368"
                     /inference="COORDINATES: protein motif:HMM:NF024502.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="integrase"
                     /protein_id="HFG9698069.1"
                     /translation="MKDRECSFSPNTIRNRKNMIKNQIEVFFKDMKLIDITPSILQSY
                     INNIYNEHMLNSIKNQVDFIKSVLKESYRLKEISENICDFVTTPIKKVVQLLSFIQNK
                     KLNYY"
     gene            10179..11534
                     /locus_tag="ACGI5H_002369"
     CDS             10179..11534
                     /locus_tag="ACGI5H_002369"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438549.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0042910 - xenobiotic transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0006855 - xenobiotic transmembrane
                     transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MATE family efflux transporter"
                     /protein_id="HFG9698070.1"
                     /translation="MDTKISINENMSLGKRFFKYLAPSVVAMWVFSLYTMVDGIFVSK
                     GVGELALAAVNISMPFINFIFAVSLLFSTGASTIIAIYLGKKDIKSANEVFSFNLVSI
                     IILSIIILAITFFNLDRLALFLGATESTIGMVKDYLGIIIFFNGFFIVSYSLEVIIKT
                     DGFPILATVGVIISALTNIILDYLFVIEFGWGVKGAGIATGLSQVFSTIFFLIHFLRK
                     NSTLNFSKFRIDFKTLRKIVFIGFPDSTTELSCGIVVLLFNLSLTKYIGENALIYYSV
                     INYINTLVLMTMMGITQGMQPLTSFYYGAGNIDNVKKLLKMGIKATIIASVAVFAICM
                     AFSGPIVSLFIHPEETMLFNEGVRVFKIFSISFLLVGINVIISGFFVSVEKPSISTVI
                     SLGRGLVIVVLSLISMILIFGGQGIWMTTIVSEFICLILSLVFLKKNFSTLDSNLNKV
                     A"
     gene            complement(11652..12311)
                     /locus_tag="ACGI5H_002370"
     CDS             complement(11652..12311)
                     /locus_tag="ACGI5H_002370"
                     /EC_number="6.3.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429358.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diphthine--ammonia ligase"
                     /protein_id="HFG9698071.1"
                     /translation="MLKLADEKFVMSFSGGKDSILALNRMLKKGYKPVALLTTISEEH
                     GKSWTHNLEYNMLKQVSSNIGLPLLVAECGVEGYEESFERALIKAKNMGATICAYGDI
                     DIESHRKWDTDRCEAVGMKVDLPLWQESREELVYEFIDSGFCSVVTKVNLKHLGEEFL
                     GKKLTRELVEKIKNAGADPCGEHGEYHTFVVDGPIFKKPVEYEVKGTLIKDGYGYLEI
                     K"
     gene            complement(12387..12815)
                     /locus_tag="ACGI5H_002371"
     CDS             complement(12387..12815)
                     /locus_tag="ACGI5H_002371"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429356.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DMT family transporter"
                     /protein_id="HFG9698072.1"
                     /translation="MTKLWAIIFALLAGGSTALEAFINGELGKSTTALVATFISLTVG
                     AIFFLASIIVTGDLKCLVSINGFNYKLLLGGVFGGLIIYFTVKAIPNLGVSNTLILTL
                     VSQVLVGFFIDSVILGQETMHLYKYIGVILLILGTFFIVN"
     gene            12967..13515
                     /locus_tag="ACGI5H_002372"
     CDS             12967..13515
                     /locus_tag="ACGI5H_002372"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014466364.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF308 domain-containing protein"
                     /protein_id="HFG9698073.1"
                     /translation="MYTNFNIDFNNFNKKENAIKFMLMGVLLIILGLLCLTFKTLGIK
                     LISWTFGIALLFFAYLNLKNINELKRYATKEEIKPSINIQWVLIIACILLFVFPQKIQ
                     SIFSLFLGFYLIFNQLVALVNSKNNPYSKFTTWNIVKILFGICLILSPLFLSRFIVSI
                     MSFFIILFGLVLFFSGNTARKY"
     gene            13634..14569
                     /locus_tag="ACGI5H_002373"
     CDS             13634..14569
                     /locus_tag="ACGI5H_002373"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893027.1"
                     /note="This family includes YhcC from E. coli K-12, an
                     uncharacterized radical SAM protein; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology.
                     GO_function: GO:0051536 - iron-sulfur cluster binding
                     [Evidence IEA];
                     GO_function: GO:1904047 - S-adenosyl-L-methionine binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR01212 family radical SAM protein"
                     /protein_id="HFG9698074.1"
                     /translation="MDKFKYAFDNKRYHTWNYYLRNTFGEKVFKVSINAGFTCPNIDG
                     SLGYGGCTYCSKEGSGDFAGNPKDNLISQFYNIKEMMLKKWPHAKYIGYFQAYTNTYA
                     PLEVLKEKYETILELEDVIGLSISTRPDCLPDDVVEYLSELNKRTNLWVELGLQTIHD
                     STSKIINRGHDYKTFVEGVEKLKSKNIKVVVHIINGLPGEDYNMMMETAKAVGKMGVD
                     GIKIHLLHVIKDTPMEKMLQNGMLTLMEQDEYINLVCDQLEILPETMIIHRLTGDGKR
                     DELVGPIWSLKKWEILNKIDDTLKARNSYQGCKFV"
     gene            complement(14840..15784)
                     /locus_tag="ACGI5H_002374"
     CDS             complement(14840..15784)
                     /locus_tag="ACGI5H_002374"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438541.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DMT family transporter"
                     /protein_id="HFG9698075.1"
                     /translation="MGEKSKGYVFIAIAGLLWATLGLFGKFLMGNGLTSEQVAFTRLF
                     FGFIVLGVYSSIRTPQILKINKKGIIYSVIIGIICQAMFNLCYFKAIDIAGVSIAAVL
                     LYTSPLFLAIFSKLCYKENITRSKLFSLILCFIGAIMAVTGGRLDFQGLNAFGLLLGV
                     LSAIAYALMPTISKNALKEFSSSTILVYSFLFGAIFMIPSSRPWEILNYAKDLDVLSC
                     MLMLGIVPAALAYIFYAAGISKGVELSVAGVVASVELVGSVIIGCTILGESFSLGKLF
                     GVMLMLISAVVALNLSYDEIRIFYKSNKLKQIEKTESI"
     gene            16102..17532
                     /locus_tag="ACGI5H_002375"
     CDS             16102..17532
                     /locus_tag="ACGI5H_002375"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729573.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0008134 - transcription factor binding
                     [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sigma 54-interacting transcriptional regulator"
                     /protein_id="HFG9698076.1"
                     /translation="MNLDLEFYQKILEASHDEICVSDDKGIIIYCNKAFEENYGLKKE
                     DILGKNVSFLEDSGYSTKSPIPIVLKTKTKFSLEQDTQTGKKLIITATPIFDENGHLE
                     FTVENCRDITELNNIKNKLEDTKKQVKKYKFEVETLYRTALRIEDTVIMDGIVMRPII
                     NTVNHVSKTDVSVLLLGESGTGKSSLARYIHHNSNRSNGPFITINCATISPQLLESEL
                     FGYTSGAFTGASTKGKVGLVELANGGTLFLDEIGDIPQNLQAKFLQLIQDRTFTPVGS
                     LKNKKVDIRIISATNVDLVSKVKEKKFREDLYYRLNVIEIKLPPLRERRDNLVEIIKY
                     YFNRYSSDFNLNKTISKEAMDAIANYRFPGNIRELQNIIQKILLTCTDNHITIDDLPN
                     ILTKNIHITNNGNKTHISQINKVIISDSKSTNYKNKNFDTLIKEYEKNIILDAYEKFG
                     SSYKVAKHLEISQSKANRLIRKYTNT"
     gene            17732..18316
                     /locus_tag="ACGI5H_002376"
     CDS             17732..18316
                     /locus_tag="ACGI5H_002376"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419819.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc dependent phospholipase C family protein"
                     /protein_id="HFG9698077.1"
                     /translation="MLMNTHFIMAKSILDNIDENKTFFISEKNFIYGNIKPDAFSKYK
                     LKKHYLDESFNMIVSKINYLCSLNIDSLSKYFSVSRLSQELGVICHFLCDFFCVAHSE
                     RWEFKHSLNKHVTYERELGAFAKDVDLSKIKCGTINSSFEKFFTKLYSDYKKKTDYMN
                     DLKFSAYTCNSVINYILDSILSNTIKSYHIANCG"
     gene            complement(18420..19199)
                     /locus_tag="ACGI5H_002377"
     CDS             complement(18420..19199)
                     /locus_tag="ACGI5H_002377"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419804.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HFG9698078.1"
                     /translation="MIKHIFCDLDGTLYENGTITKEDIVAIEEIEKKGVQFNVATGRI
                     FKQAHNIIKDSLDMNGYYVCENGSFIYDKDYNVIFKRTIDDNLVKKVIDRFESSDAQL
                     YFKYKGDVIVGSDTTAFRHYSSDFIVDPDFEKRSSFDNLIGNIGVCSENLEELSRIEL
                     YLKSEFSEVLEIYFSGTYTLNIVPKSVSKRGSIEHVIKTLNVSPDEVATIGDSPNDIC
                     MLEGFKYSFAMSKAREDVKQSANYVVDSVKSAIDVIMEINS"
     gene            complement(19257..20513)
                     /locus_tag="ACGI5H_002378"
     CDS             complement(19257..20513)
                     /locus_tag="ACGI5H_002378"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438532.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence/damage-inducible protein A"
                     /protein_id="HFG9698079.1"
                     /translation="MKAEIISVGTEILLGDIVNTNSQFLAKELASLGIEVYHQSTVGD
                     NKQRLLECFDESLKRSDFVITTGGLGPTGDDMTKETAAEYFGQKLELHKPSLEVLESF
                     FVKTGKKMAENNMKQVYFPKDAIVLKNNNGTAPGAILKKDGKFIIVLPGPPREMKAMF
                     NESVKPYLQQFTNEMLVSKTLRLYGIGESNLELEILDIINEQTNPTVALYAKELEVTI
                     RITAKAENEREAFKLIKPVEEKIKSRVGKYVYTEGDISISEGETALEDAVSKLLVEKN
                     LTIAVAESCTGGLVSSSLINYPGISSVFLEGCVTYSNDSKMKRLGVKRETLEEFGAVS
                     EQTAIEMAEGIAKGLKANIGISTTGVAGPGGGTKEKPVGLVYTAIYINGKTIVKKNIF
                     NGDRRKIRLRATRDLLNELRIQLEKL"
     gene            20771..21670
                     /locus_tag="ACGI5H_002379"
     CDS             20771..21670
                     /locus_tag="ACGI5H_002379"
                     /EC_number="6.3.2.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429344.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0008716 - D-alanine-D-alanine ligase
                     activity [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0009252 - peptidoglycan biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanine--D-alanine ligase"
                     /protein_id="HFG9698080.1"
                     /translation="MKIAVIMGGISSEREVSLNSGKEIYNNLDKNKYEVVKVIIDDKK
                     DIFTKIPEDIDFAILALHGKFGEDGCIQSILETMDIPYSGCGPLCSGMCMDKNITKKM
                     LRDSNLPTAPWVLVKSVDEIDYDEIDNIGYPVFIKPNSGGSSVATFFIHSKDEVEEAV
                     RKGLEVDEFVMIEKYIPGGEYTSFILNGEVFPTISIKSDSGFFDYEAKYSVEKGAKEE
                     VVYLDEELQKRVNEISETCWKIFNCKAYVRVDMIISEGIPYVLELNTLPGMTQTSLIP
                     RSAAARGIKYSELLDKLIEYSLN"
     gene            21694..23142
                     /gene="ddlR"
                     /locus_tag="ACGI5H_002380"
     CDS             21694..23142
                     /gene="ddlR"
                     /locus_tag="ACGI5H_002380"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902483.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator DdlR"
                     /protein_id="HFG9698081.1"
                     /translation="MIFSNLKLNDNEPIYIQLKNYISDMISKGLIPDNSKLPSTRELS
                     QLLQVSRNSVVLTYEELKSEGLIYSISGKGTFVKSKNKSSNTTWSLNWDCLENTYSKK
                     ANELDIIKSEIPWSSDLISFKSISPDGDLFDMEELKKSFLNRISLEGHKLLNYGYAQG
                     YKPLIDYLLEYMTNKGADISNKDILITNGFTEGFDIIMSSFTQEKDYIICENPTHNTA
                     IKIMKSHNLNILGVDINEDGLDFNMLEDNLVKYKNKIKFAYITPSYHNPTGIVMTPEN
                     RYKFYNLMKKYNIAIIEDGFNEELLYNSSHIFPICSLDNMNNGVVYIGSFSKILFPGM
                     RIGWIFADKKVINKLESVKRCRNIHVSFLDQGILFDYLSNGGFEKYIKKIRKFYGDKF
                     NFAYKCIKKYIKTEYILGDGGLHIFIKLKNIDTRVLLEKCYEKNVIFMPGDLFFTDNS
                     GFDTLRLGFSRLSFEDIEIGIKIIGETINEMF"
     gene            23225..24007
                     /locus_tag="ACGI5H_002381"
     CDS             23225..24007
                     /locus_tag="ACGI5H_002381"
                     /EC_number="3.4.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889203.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA];
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="M15 family metallopeptidase"
                     /protein_id="HFG9698082.1"
                     /translation="MSKKSKRRKINKLKLTIVITVLFLALLSIYEILFSNPNKKGNIK
                     SQETMQNKNNTTDDSKNNQSSTKKQEDNNIKPTFSYSSIPDNIKNKMIGKSMPTDEPI
                     SFDSLSYLKLTYYGFDEKTHQGEMIVNSELAPEVVDIFKELYEKKYPIEKIKLIDDYD
                     AVDEKSMSDNNTSSFCYRTIAGTNVVSNHGKGRAIDINPLQNPQVSGNDVTPKVSTVY
                     ADRSSTKFGMIKKGDDCYNAFVSRGWSWGGYWKNPDYQHFEK"
     gene            24033..25952
                     /locus_tag="ACGI5H_002382"
     CDS             24033..25952
                     /locus_tag="ACGI5H_002382"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="HFG9698083.1"
                     /translation="MNLMTLENISKSYSEKKLLENISLGINEGEKIGFIGVNGTGKST
                     LLKIIAGVEESETGNITKTNGIRIEYLPQNPTYNENSTVLEQVFNGTSEELKLLGEYQ
                     EILEKLNSNFTEELNKKLLSVHEKIDALNLWDLESEAKSVLTKLGINDFNQKIAELSG
                     GQRKRVSLASALITPCEFLILDEPTNHLDNDTIDWLEEYLNSRKGSLLMITHDRYFLD
                     RVTNRIIELDKGRLFSYDGNYSIFLEKKMERLSLEASIEDKRQNLIRTELAWVRRGAQ
                     ARSTKQKARLQRFDELINRDSFKPDENLDISVASSRLGNKIIEIHNISKSFEENTVID
                     NLEYTLTRTDRIGIIGKNGMGKSTLINILNGEIEPDSGYISIGETVKIGCFSQDDSHM
                     NIDMRAIDYVKEASDYIETSDGTRITASQMCERFLFNGTMQYTLIGKLSGGERRRLHL
                     LKILMTAPNVLLLDEPTNDLDIETLKILEEYLDEFKGVVVTVSHDRYFLDRICNKIFA
                     YEGNGKIHIYTGNYSDYLIYREIQGIEFEESKRESVKKDDSTTPKKEKPKNDKKLKFS
                     YNEQREFENIDSDIEKLESKIATLDESTAKFSTDFTKLQEILDEKSKLEKELEYKYER
                     WEYLNNLADEIANNK"
     gene            complement(26194..26541)
                     /locus_tag="ACGI5H_002383"
     CDS             complement(26194..26541)
                     /locus_tag="ACGI5H_002383"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419773.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PqqD family protein"
                     /protein_id="HFG9698084.1"
                     /translation="MSKSNDVLDIVFKITDGLEYEVAENRVVTILEKQDHKIQKFFRK
                     LKARIPKYKKIELDEYSSFVFLQIDGQRTVREIGKNLEAKYGEESHPLYERLLVFLNH
                     IEVNCHYIERLDI"
     gene            complement(26528..28456)
                     /locus_tag="ACGI5H_002384"
     CDS             complement(26528..28456)
                     /locus_tag="ACGI5H_002384"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902476.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0035673 - oligopeptide transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0006857 - oligopeptide transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="OPT family oligopeptide transporter"
                     /protein_id="HFG9698085.1"
                     /translation="MNKKLPKGAYGEVSGKDYVPYITDKSRTGGNVAVLIIGIILAAI
                     FAASTTYSGMKAGLTVAAGIPGAIIGSAFVGAFARSKGILGKNLIQGMSSGGESVASG
                     FIFVLPAVILIGSQITFLEGLAVGVGGVLFGIGIAAIVHNYLIVEEHGKLMYPESMAI
                     SETLVASEAGGDSIKYMGIGFVISGFITVLTGSFLNVANNVMSLVGSKFYKWKFDIEV
                     NPLLLGIGFIVGLEVSLTMFAGSILSNFGIAPLIGYFTDMAKDGAMVWNNPAMPLNQM
                     DVGAISSSYVKYIGAGMMLCGGIIGAIKLIPTIIASIKETLKAKSSAGEGEEGSSIQM
                     ILLLGGVVIGFLAAFLISGNIVMAIIGAIISLLLSLLFVIVAGRLTGTIGTSNLPVSG
                     MTIASLVIVTLVFVIMGWTDLEANKSLLLFGSFIVVAIAIAGGYTQSQKVTYIIGGSK
                     NEMQRYFTIASIVGVIVVVGVILLLSDQLRATGDNVQFALPQANLMSTLTSGIMSGSL
                     PWVMIIVGVFMAIVLYALNLPIMTIAIGFYLPIATTSIILVGALIRLFVELVSKTEKE
                     KEVKVSNGISLSSGLVAGGSIIGLIGIILQVTGVVTPKVPSGFAATNSMAIALLVVLV
                     VLTALPIVLSKVKNNEQE"
BASE COUNT        10889 a         3923 c         3720 g        10097 t
ORIGIN      
        1 ttataaatat attttagttt tatatagttt tatgtttaca gctattatat ccatctctat
       61 gtaatatttt tcatattaaa actgatttct atagattaat agtttataaa tttagtaaat
      121 gaatatttat tatagtcttt aacaaaaaat acaagaataa acttaatttt aataactaaa
      181 attaattatg caaaattatt aatatggtat taaattatgt ataaaaagtt aattatgaat
      241 aaaataatta tgcctttgaa aaatcattaa acttaaaatt aattataaaa aaactctacc
      301 ttactaacta tacagctcac aatctatcta tttatgaaaa aatatgatat aattgcattc
      361 aaaaaggaaa tctttcaata tactagaatt taagcattaa ctaattttat ctaatattat
      421 tactaaacta aaaaatattt gtatttgtag cattggagca aataacttaa tgtatattca
      481 ttttaaatac ttatttaaaa tttagcattt aaattattta caaattaaca tttaaatact
      541 tctagcataa atacagttgt catcaaaatt taaagtatct tatggaggaa taccatgcaa
      601 aatcataatt atataaaaat gttaaataaa aaggtagaag tattatctaa ggaattagat
      661 agtagaaatt ttaaattaaa aaccttaaat gaaatagatt ttttttctaa aataccaaac
      721 agagaattta tgtaccaaca tattgatgac tgtatttcga aaaatataca tataggaatc
      781 atgttattaa atatcgataa ctttaaatta tttaatgata tatatggata cctagtcgga
      841 gaaaatttat taattactct aactcaaaac ctattgcact ttattccaga atcaaaggga
      901 atagtcgctt atttaaaagg agaaggtttt ttaattgtac ttccaaatgt atcaaataaa
      961 gagttaaata atatgggtgc aactattata gagagcgccc gagaattaaa aataagactt
     1021 cctaatgaaa aagaaatata ctccaatgtt acatttagta tcggcagcac tatctggaat
     1081 ggtgaaccaa acatgactac tttgatgctt ttcaaccaag tgtatagtgc tttaaaaaag
     1141 gctaaaagtg aaggtaaaaa tagatacatt ctatttgatt ttaaagataa tagtttttac
     1201 aataaattag aaaatgataa ggagttctta tcagaaatat cacatgttct acaaactaaa
     1261 caaattgaag tattttacca accactttat aatataaaaa ataatactat agttggatgt
     1321 gaggcacttg caagatggag acaccctatt aaaggacttc ttactccaga taaatttatt
     1381 cctttatttg aacagtttgg tctgataacg gaattagatt tgcatttatt tgaagagaac
     1441 tgtaaaaata taagaagatg gattgataac aatgatgttt ttgttccaat ttgttgtaac
     1501 ttttctcgtc ttcatttttt taaccctaat tttccaagta tgctaaaagg tattactgaa
     1561 aagtacagcg tctctacatc aaattttagc attgaaataa cagaaaatat attaatagaa
     1621 aatacaaata caattattca acaactagct gaacttcgtt cttatggttt ttctgtatca
     1681 atggacgatt ttggttctgg atattcatct tttggtatgt tgcaaaatct accttttgat
     1741 ataatcaaaa ttgataggat atttttatct cataatttaa atgattttaa aaatacaacc
     1801 attttgtact ctataataaa cattgcaaga gctcttggga tgcttacagt atgtgaaggt
     1861 gttgaaacag aacaacatgt agaatttatt aaaagtataa attgtgatat cgcccaaggt
     1921 tattattatg caaaacccat ggagtgcaaa gaatttgaaa aattactatc taaagagaat
     1981 aattcagaga aaatgtttat aaaatattct gatataggaa aatctttaat agagaagata
     2041 tttgatggat tttttattat gcaagatatg aaaaaactaa gagctaatgt cactgaagac
     2101 attcaatggt ttgattttta caacaaaact gaaattacat cttttcctaa agtaatagag
     2161 cattttgaaa aacatattaa aggtaaaaaa ttttctattc tttacaaaag tataacccca
     2221 cataatactg aatcagattc attattaatt agtggagaag ccgttttatc agatgaagct
     2281 tctgaacatc aaaaatatag caatttctac tttagtgcaa attgtataat ttcagaaaat
     2341 aaattactct tagcaaaatt acatttggat ttaattaaaa ctgctggcta tataaatgaa
     2401 tttgaatcat attcaatacc taaaatgaca aatacacatc ttgatgaaag taatatttta
     2461 tcacaatttt attcaatgtt gcctgtaggt ataattcgct acgatttatt tggtgatatg
     2521 attattactt atatgaatga agaaatgttt gatattatag gttatacaaa agaacagttt
     2581 tttggtgaga tgggcggaaa tttaagagca attgttcatc cagatgattt agactttgtt
     2641 tataaaaaaa gtttggacat gattgacaca aataaaattg aaccattttt atatagattc
     2701 ataaaacgag atggtcaaat tgtcacagtt atgtatacac aatgtaacct ttctgcaatt
     2761 gatggaaggt cgattgccca gggtatgtat gtagatgtaa ataaaataaa aaatttaaca
     2821 aaaatctagt acaaagtatt ttattttgga gaaattaata tgtttaaaga aattttttta
     2881 agaacttttc caggatttct aattataaga gattctaact acagaattat atttataaat
     2941 gataatttaa aaaatttaat taaaagttat atgcaagata atccacttgg aatgactaat
     3001 atagaaatag ctaagaaact ccctgataat attgctaaat tttttacgga ttctcacaat
     3061 attcaattag attgggaaaa aaattatcct tatgataaaa tttcaaattg gattttagag
     3121 tttaaaaaag atactacaag ctattggaat gttttagaat acaaagtaga tgttgatgaa
     3181 aaaacctaca taattactat ggccaatgat ataacaaaac tctatgaaga aaataagaga
     3241 aatcttcact actcaattac tgacccatta actggagcat ataatagaaa atatttaaat
     3301 gatagatttg acatatttat aggagattat attgtactaa ttgacttaga taatttcaaa
     3361 atgataaatg actatgaagg tcataatgta ggagacaaga ttttatgtga ttttgtttca
     3421 cttttaaata aagaattaat aaattctact tctattatac gattaggagg agatgaattt
     3481 attgttatat tctctagtga tgttgacaaa aattatgttt attcacagct agaagcctta
     3541 agagaaaatt ttttaaaagt attctctaag tataagtatc tttcatttag ttatggtgtt
     3601 gatacagtaa aaagaaattt aaaattgaca atagttgaat tggataaaaa aatgtataaa
     3661 aacaaggaga aaaacaagaa aaaatttgat aaaaatgatt attaacattg ttattttaaa
     3721 ataaattaaa attatctttc tttttttaaa cttgtacatt agtttataaa tatgtatcta
     3781 tacaagatat tgacattaag tactgaagca tatattgttt cagttctttt ttgttaaaat
     3841 taacttattt aacaaagata tcatagttta acaaagcttt taatttaaat atattgatgt
     3901 ataatataat taaaatataa tagcaaaaag aaaggaggaa tatcatgagc atactcctaa
     3961 aaaaagcacc caaattagca aaacatatta taacaagttt ttatataaat cgagatatca
     4021 atgaagtatt aaaatacctt tgtgaaaatg ttacatggat tggaccagga gaacaggaat
     4081 ttctcacttc ttttaatgaa ataaaaaatt atttttatgc aggtcaagat gaaattcctt
     4141 cttgtgatat aaataatgat atatttgaaa ctgtaagtga agatgagaat agatgtatgg
     4201 tattaggaag atatactgtt cgaactaaag aaaatgctca aatgatttta gaggtaaatc
     4261 aacgttgtac atttgagata attgaggata gaggaaaatt attaataaag cacatgcaca
     4321 tatcaaaccc ttatggtgaa atgcaacttg atgaatactt tcccactaaa attggaactc
     4381 aaagttatga ttatttgcaa agattactaa aagaaaaaac agaagttatt gaaatgatta
     4441 caaataatat caatggtggc ttaaaaggta gcaatgatga tagtacatac tcatttttct
     4501 atgtcaatga gggattgccc aaaatattag gatacacata tgatgagttc atggaaatga
     4561 gtggtggttc agcagtgggt gctgtatatc caccagactt acctaaagca ctagaagatt
     4621 gtgaacgatg ttttgcaaaa ggacctacat attcatctga atatagaatc cgaaaaaaag
     4681 atggaacatt aatgtgggta ttagattctg gaatgaaatc gttaaatagt gatggcatag
     4741 taaaaattaa tagtattatt actgacataa cccaactaaa aaacatagaa tctgaactaa
     4801 aattagaaag agagcgatat cgtattgctt tgcaaaatat tacagatatc atgtttgagt
     4861 atgatattga aaacgatacc cttataaaat atcaacgtgt agaaattgac aaaaaaattg
     4921 aattagaaaa ttttgaaaca aaaaattact ccaaactatt agaatctggt aaaattattc
     4981 accttgatga tattggaaaa ctactagaag tacttcatgg aaatcttcgt gaaacaattg
     5041 agataagaca agtaaattca ttaactaaaa atgaatggag atggattcgt gttcaatgtt
     5101 cagttatata tgatagtgac cataacccta tcaaaacaat aggcgtttta aaagacataa
     5161 ctgaagataa atctaaatta gaaagtttaa ttaatcaggc tcaacgtgac ccactaacac
     5221 aattatataa tcaaagagta tcacaaaatc ttattgaaga gtatctatgt agttctgatt
     5281 ccaaaaataa tgatgctcta ttagttattg atattgatga ttttaaaact gtaaatgata
     5341 cttttgggca tctagaggga aatgaagttt tagttgctgt atcaaaaata ctattacata
     5401 acacacatga taaagacata gttgctcgaa ttggtggaga tgaatttaca atatttataa
     5461 aatcattaac aaaggattta ataataaaaa ttactaatga tattttaaat gatgcgagta
     5521 aaataaaagt aaaggacaat cataaaataa cattaagtat tggtattgcc ttcactgatg
     5581 attcaactaa attatataaa gatttatttt ctaaagctga taaagctctt tatctatcaa
     5641 aagcagatgg caaaaattgt tatagtacat acgaataata aagctattta tacgaccaag
     5701 aatgaacctt taaatttaat ttcatagtct aacaatcaaa gagttgaagc taatcttata
     5761 gctagtcaac tagttcctag aaaaaattta aacaatatat ttattgatac tgctcatttt
     5821 tctaaagagc aaatttatat aaaaaattaa acttttatat acatacagat actaatgata
     5881 aacagttatc attagtatct tctatcttaa aacaaaatga taatttatct atataaaaaa
     5941 gtgctttgtt gacagagttc acttttttat ataggtacag aatttaagta taaatacatg
     6001 ttttattcta tacattttag ttaatgtaaa atttcttgat tgtactctct aacttttcaa
     6061 cattatacta tttatatacc acttagttaa tataaaacta taaaagtgtt gcaattactg
     6121 ggttttataa agttaattta cataccactt agttaatata aaactttagc accttattta
     6181 tctatagagc tacagaaagt atttacatac cacttagtta atataaaaca tgtatttatt
     6241 tgttcttgta ctattgtttt actctattta cataccactt agttaatata aaacaatatc
     6301 aaaacaaata aaaattttta ataaatcatt atttacatac cacttagcta atataaaaca
     6361 ttctggtact gttgctattt atgttccgta ttcagaattt acataccact tagttaatat
     6421 aaaactttgg agttgttaca gattatttgc cttatctctc tatttacata ccacttagtt
     6481 aatataaaac ccccaaataa actgggcatt ttcaatactt acacatatgc aactctctta
     6541 aatttgcagt gaaccatgag tagtgcaaat gataaagctt atcatatacc ctcaacacct
     6601 tatatttcaa gcgttaagct ctactttgta acaaatatcg ctcactgcaa aactatttac
     6661 atttttatta tatcataaat atattatttt tgaatatcta taccaatttg tggtataata
     6721 aaagcaagaa gaactacaat ctatttagac gtagagtgaa gttcaaatac taatgtttat
     6781 tctttttgaa cttgattttt agttcaaaac taaagtcact cctgcctgtg tgaactatac
     6841 ccgctgtttt atacagttaa aacatgtaaa aatagttata aagtactagt gtaactcatt
     6901 agtactcttt ttattatatt catataatta atatctatat tttaaagctt actatctaaa
     6961 aaagagcacg tcaaataaaa ccctagatat ttaatttttt tagagatact taaaataaat
     7021 tatgctctct ctgtacttaa atatttccta aattcaaatg gagacataga atttaatcta
     7081 ttttgatatc taaaattatt atagtagtat atataatcat ctattgcttt aactaattat
     7141 tcatatgtat caaatttcct taaatagtac atttctacct ttaaaattcc ccaaaatcct
     7201 tccataggag cattgtcaag gcaacgacca actcttgtat aatatatgta tatctaacac
     7261 cattaagaaa tatatatttt ataatatata tttcttcatt taatgcactt agaaaagcaa
     7321 agaaaataca gattagtaca ctttttagag aaaaataaaa ttaatacatc taaaatatta
     7381 aaaaatactt tagataatct aaagacacat ctcaaagttt ttaactaaat tataaaacta
     7441 attacaaatg ctatgtaacg ataataaata aaaaatttac ttcgcttaag cgacgtgtcg
     7501 ttgaaatatt tcatgttgcc aactgattca taagtcgata agaaaagaac actaattatt
     7561 tagagttctt ttcttagcta caagtggatt ataatacttt taaatctgtg agaaaatcat
     7621 atataataat gatatgaaca agtaaagaaa atacaaaaat gacaaaatta taaataaaat
     7681 attataaaat cataaggtca taattgttat attgtagaaa caaagtaaag agagagggtg
     7741 gagaataaat gaatcaaaaa aaaataaaga ttagtattaa aatggtaatt ataggtatat
     7801 tttctgtaat tattgctttt gtattatcca gattattcgt tgagtatatt gatgaattat
     7861 taaggtctaa ttggcaatat cagctatttg aaagtgagag ttcatatata atatttgcca
     7921 attgtattat gttctcgaat atattattag aaatattttt aatatatatt tgtagaaaat
     7981 ttagaaaaat ctaatatggt caacgtattt cgaatcgaat acttcatgat tatttagtct
     8041 attgtgctag ttaaagttta attcccatat aaagtaaatt gattttagta aaacaaatca
     8101 cccctaaggg ttagtttatg gataagtcat ccaaatatta actctttaat ttttgctata
     8161 gattcatctt tgctcataac tttacttata aaaaatgaaa tattataagc tagaactttt
     8221 attctaattc tagtcataaa tcctagcata gagttacttt ttttatatta taaataaaac
     8281 tatacaacaa agataatatt tagtaaaaat aactttcatt ttaactaaac ttaaaattca
     8341 attactctct aaattgacgt ttaggaatta gttcaaaata aaaaagagtg tatatattga
     8401 aattactaca tttcaatata tatactcttt ttaaatttct cagttttcca tggaacttta
     8461 ctttatttat ttctgtatta gttgtatttt ttatgcattt ttctttaaaa tcatattttc
     8521 tgattcaact cttatattat aaaatttctt tactaaatta ttctcttttt ctatatcttc
     8581 atatatattt tttaatcgcc ttttacctaa tcttttatct aacattacta atgatttaac
     8641 taatatatta tatgatttta tcgcatcttc tattgagata tttaaacata tatttactgc
     8701 ttcataaaaa tcaaattcat taaaaaatcc atttttattt acaatcttat atccctttgc
     8761 atctctttct aaatactctt cctaaatact cttcaaaact ttcatcatct aatctaaatc
     8821 ctatatcact atgaaaaata ggttttgcat ttggatatag ttctattgtt ttatcaaaag
     8881 tttcgaatac caagttatta ttattcgatt ttccaatagt ccactataaa caataataag
     8941 tttgttgctc caaataatgt aacacttgta gaaagatgtt acagatatat aaaagataga
     9001 gaatgtagtt tttctcctaa tactattaga aatagaaaaa atatgattaa aaatcaaatt
     9061 gaagttttct ttaaagatat gaaattaata gatataacac cttctatttt acagtcttat
     9121 ataaataaca tatacaatga gcacatgtta aattcaataa aaaaccaagt cgattttata
     9181 aaatcagtat tgaaagaatc ttatagatta aaagaaatat cagaaaatat ttgtgatttt
     9241 gttacaaccc caatcaaaaa agtagttcaa cttctaagct ttatacaaaa caaaaagctc
     9301 aattattatt agaaaaatca aaaaatattc ctataggtat accaattttt ttgatgctaa
     9361 ctcttggatt acgttttggt gaagctgtat cacttatatg gtcagatgta gaccttgata
     9421 aaaaatctca catgtaaatc aaacattagt ttatgtatac aataaaataa tcttcaaaga
     9481 ccctaaaacc cctatatcaa aaagaaaatt atttgctcct gatgaactta taagtttgct
     9541 taaaggggaa aaattaaaac aaaataagtt aaaattacag ggtatattga aaaatgaatt
     9601 tgatttgata tgcttaaata aaagattcaa cccgtgagtt caaccaactt ttgttgttca
     9661 ttttaaaaaa ctattaagag ataataatcc tagagatata aaagtacatg aattaataca
     9721 tgcaaatgca actttgatat tactttcagg tactaacata aaagctattt ataaaatatt
     9781 agtacatgca gatataaaaa tagctatgaa tatatattcc atattctcac ttattagatg
     9841 aaatgaataa agaaacatct gaaaatataa gcaaaatact attcaaataa tgttcagttt
     9901 tatgtcaatt aaatgtcact caaagtgctt ttttttcatt tgtcagttaa atgtcactta
     9961 aagtaccttt ttcctatttg tcagttaaat gtcagtaata tataaataag atatatttat
    10021 aagaccctta aaatcactat tatttaataa aatttataat tatatactat ttgctgttga
    10081 cattggtatt ataccatagt ttatcattta tattagaaat aaaattatta attaatagtt
    10141 tcgtaatttt ataatagatt tacagggagt gatagtaaat ggatacaaaa atatctataa
    10201 acgaaaacat gagtctaggt aaaagatttt ttaaatacct agcaccatct gtagttgcaa
    10261 tgtgggtttt ctcactatat acaatggttg atggaatatt tgtaagtaaa ggagttggag
    10321 aattagcttt agctgctgtc aatatatcaa tgccttttat taattttata tttgcagttt
    10381 ctctattatt ttcaactggt gcatctacca taattgcaat ctatctgggg aaaaaagata
    10441 ttaaatctgc taacgaagtc ttttcattta acttagtatc aataattata ttatcaataa
    10501 ttatattagc tataactttt tttaatttag atagattagc actattttta ggagctacag
    10561 aatctacaat tggtatggtt aaagattatt taggaataat aatatttttt aacggattct
    10621 ttatagtgtc ttattcttta gaagttataa taaaaactga tggctttcca atattagcta
    10681 ctgttggtgt aataatatct gctcttacaa acatcatact tgattacttg tttgtaattg
    10741 aatttggatg gggtgtaaaa ggtgctggta ttgcaactgg tttgtctcaa gtcttttcta
    10801 ctattttctt cttaatacat tttttaagaa aaaactctac tttgaatttt tcaaaattta
    10861 gaattgattt taagacactt agaaaaattg tatttatagg ttttcctgat tcaactactg
    10921 aattaagttg tggtatagtt gttttacttt ttaacttaag tcttactaaa tatattggag
    10981 aaaatgctct tatttattat agtgtcataa attatataaa tacattagta cttatgacta
    11041 tgatgggtat aactcaaggt atgcaaccac ttactagctt ttattatggt gcaggaaata
    11101 tagataatgt aaaaaaatta ttaaaaatgg ggataaaagc cacaataata gcatcagttg
    11161 ctgtatttgc aatttgtatg gctttttcag gaccaatagt ctctttattt atacatccag
    11221 aagaaacaat gctattcaat gaaggagttc gtgtatttaa aatattctct atatctttct
    11281 tattggtagg aattaatgta ataatttctg gattctttgt atcagtagaa aaaccatcaa
    11341 tttctactgt tatatctctt ggtagagggc ttgtaatagt tgttttaagt ctaatttcaa
    11401 tgatactaat atttggtgga caaggaatat ggatgactac tattgtttct gagtttatat
    11461 gtcttatttt atcattagtt tttctaaaaa agaatttttc tacattagac tctaatctaa
    11521 ataaggttgc ttagatgata agagtgacaa tatatgaaaa tatctaaata aaaaatacct
    11581 attatacaat cttgcaaata ttaaaccttt gcaaaaatta ggattatata ataggtattt
    11641 tatttatgta attattttat ttctaaatat ccatagccat cttttattaa agttcctttt
    11701 acttcatatt ctacaggttt tttaaatatt ggaccatcta cgacaaatgt atgatactct
    11761 ccatgttctc cacatgggtc tgcaccagca ttttttatct tctccacaag ttctctagtt
    11821 aatttttttc ctaaaaattc ctctcctaag tgctttaagt ttacttttgt tacaacacta
    11881 caaaatccac tgtctataaa ttcatatact aactcctctc tactctcttg ccataatggt
    11941 aaatctactt tcataccaac tgcttcacat ctatcagtat cccattttct atgactttct
    12001 atatctatat ctccatatgc acatatagtt gctcccatgt ttttagcttt tattaaagcc
    12061 ctctcaaagc tctcttcata tccttctaca ccacactcag caactaataa aggtaatcct
    12121 atattgctac ttacttgctt aagcatatta tattctaaat tatgtgtcca tgactttcca
    12181 tgttcttcac ttatagttgt caagagtgcc acaggcttat atcctttttt caacattcga
    12241 tttaatgcta atatactatc cttaccacca ctaaatgaca ttacaaattt ttcatcagcc
    12301 aattttaaca cctctttcat ctaactttgt tttattaaca taattatacc aaatttttga
    12361 gttgcatagc aaattatatt aaattgttaa ttcactataa agaatgtccc taatattaaa
    12421 agtataaccc ctatgtattt gtataaatgc attgtttctt gtcccaaaat tacgctatca
    12481 ataaaaaatc caactaaaac ttgggataca agagttaata taagtgtatt tgatactcct
    12541 aaatttggaa ttgcctttac tgtaaaatat attattagac ctccaaatac tcctcctaat
    12601 aacaacttat aattaaaacc atttatagat actagacact ttaagtcacc tgtaactatt
    12661 atacttgcca aaaaaaatat tgctcctaca gttaagctta taaaggtggc cactaatgct
    12721 gttgtacttt ttcctagctc tccatttata aaagcttcaa gagctgtaga accacctgct
    12781 aataatgcaa atattattgc ccataatttt gtcatggaca aacctccttc tatataattc
    12841 tattaataga agtttatgat acaacctatt aattaattac taagtatagt ttaattttta
    12901 tacactaggc tttatttgga tatgaatttc tgttataatt gttctatcga ttttggaggt
    12961 gattttatgt acacaaattt taatatcgat tttaataact ttaataaaaa agaaaatgcc
    13021 attaaattta tgttaatggg agtattactc attatattag gattattatg ccttacattt
    13081 aagacattag gtataaaatt aatttcttgg acttttggta ttgcactttt attctttgca
    13141 tatttaaatt taaaaaatat taatgaacta aaaagatatg ctactaaaga agaaattaaa
    13201 ccctctatta atatccaatg ggttctaata attgcatgta tattactttt tgtatttcct
    13261 caaaaaatac aaagcatatt ttcattattt ttaggatttt atttaatctt taatcaacta
    13321 gtagcacttg taaatagtaa gaataatcct tattctaaat ttacaacttg gaatatagtt
    13381 aagattctat ttggtatatg ccttatatta tctccacttt ttttatctag atttatagta
    13441 tcgataatgt cttttttcat aatattattt ggactagttc tatttttctc tggaaataca
    13501 gcgagaaaat attaattatt ttctcgctgt atttttatat tacttaaaat agaatttgtt
    13561 taagttatct atttgtggta atatgttttt tgtacaagct cagcgtacaa ttttattaga
    13621 aataggtgat tttttggata aatttaaata tgcttttgat aataaaagat atcatacttg
    13681 gaattactat cttagaaata cttttggaga aaaagttttt aaggtatcta taaatgcagg
    13741 atttacttgc ccaaacattg atggaagtct tggttatggc ggatgtacct attgtagcaa
    13801 agaaggctca ggtgattttg ctggaaaccc taaagataat cttatcagtc aattttataa
    13861 tataaaagaa atgatgttaa aaaaatggcc tcatgcaaag tatattggct actttcaagc
    13921 ctatacaaat acgtatgctc ctcttgaagt tttaaaagaa aaatatgaga ctatattaga
    13981 acttgaagat gtcataggtc tttcaatatc cacaagacct gactgtttgc cagatgatgt
    14041 tgtagaatac ttgtctgaac taaataaaag aaccaattta tgggttgaac ttggacttca
    14101 aacaattcat gattctacat ctaaaattat aaatagaggt catgattata aaacatttgt
    14161 tgaaggtgtt gaaaaattaa agtctaaaaa tataaaggtt gtcgtacaca ttataaatgg
    14221 tcttcctggt gaagattata atatgatgat ggaaacagca aaggcagttg gtaaaatggg
    14281 tgtagacggt ataaaaatcc atctattgca tgttataaaa gatactccta tggaaaagat
    14341 gttacaaaat ggtatgttaa ctcttatgga acaagatgaa tatatcaatc ttgtctgtga
    14401 ccaattagaa atacttcctg aaactatgat aatccataga ctcactggtg atggtaagag
    14461 ggatgaacta gtaggtccta tatggagcct aaaaaaatgg gaaattttaa ataaaattga
    14521 tgatacttta aaggctagaa attcttatca gggctgtaag tttgtttaat acaaaataat
    14581 aactatagaa atggttatac aaatatagtc ctttctatag ttatttagta tttacaaaac
    14641 aaaatattaa tttgtacatt tatacaatat ataataaaaa atagatagtc taaactgtat
    14701 ctacttatat tttatttgta ctgtccactt tattctataa aatttataaa tagttatttt
    14761 ttaataccaa atataatttg gtataatttt tgttggaatc tacaatgtat accaataaat
    14821 cctttttaag tatataattc taaatacttt cagttttttc aatctgcttt aacttgttgg
    14881 acttataaaa tattcttatt tcatcataag aaagattaag tgctactact gcagatatta
    14941 acatcaacat cactccaaat aacttcccta aggaaaaact ttctcctaat atagtgcaac
    15001 caattattac tgaaccaact aattctactg atgccacaac acctgcaact gacaactcta
    15061 cacctttaga tatacctgct gcataaaaaa tatatgcaag tgcagctgga acaatgccta
    15121 acattagcat acaagataaa acatctaaat ccttagcata atttaagatt tcccaaggtc
    15181 ttgaagaagg aatcataaat atagctccaa ataagaaact gtatactaat attgttgaac
    15241 ttgaaaattc ctttaaagca tttttactaa tagttggcat aagtgcatat gctattgctg
    15301 ataatactcc aagtaaaagc ccaaaagcgt ttaaaccttg aaaatccaaa cgtccaccag
    15361 tcactgccat aattgcacca ataaaacaaa gaataagtga aaataatttg cttctagtaa
    15421 tattttcttt ataacataat tttgaaaata ttgctaaaaa cagtggtgat gtatatagta
    15481 aaactgctgc aattgataca cccgcaatgt caattgcttt aaaataacat aaattaaaca
    15541 ttgcctgaca tataattcct attattactg aatatataat tccttttttg tttatcttta
    15601 agatttgtgg tgtccttata gatgaatata cgcctaaaac tataaatcca aaaaacaatc
    15661 ttgtaaatgc tacttgttct gatgtcagtc catttcccat taaaaacttt ccaaataatc
    15721 caagtgtagc ccataataac cctgctattg ctataaatac atacccttta cttttttctc
    15781 ccattttaaa ttcccttcta tttttattta gtcaatttac actcttcttt ttaagcaaaa
    15841 actatgccat cttaaatcaa tatatatcga ctctaaaacc ctagtctttc caataatact
    15901 aataaatttt caattttttt atatttattt ttcgcttact ttaagttgat ttagacttat
    15961 tttaattgta aaatgagtta tatataactt atttaaagtt aaaatagact gaaacttata
    16021 tataaatatc aaattttaag tatattaatc aattaaacct attttaatat atcattaaaa
    16081 atttaggagg aaaatataaa aatgaattta gatttggaat tttatcaaaa aatattagaa
    16141 gcttcccatg atgaaatatg tgtttctgat gataaaggaa taataatata ttgtaataaa
    16201 gcatttgaag aaaattatgg tctaaaaaaa gaagatattt tgggaaaaaa tgtttctttt
    16261 ttagaagact ctggatattc aacaaaaagc cccataccaa ttgtattaaa aacaaagact
    16321 aaattttcac tggaacaaga tactcaaaca gggaaaaagc ttatcataac tgctacccct
    16381 atatttgatg aaaatggaca cttagaattt actgttgaaa attgtagaga tataactgaa
    16441 cttaataata taaaaaataa acttgaagac acaaaaaagc aagtaaaaaa atataaattt
    16501 gaagtagaaa cactatacag aactgcactt agaattgaag atactgtaat tatggacgga
    16561 atagttatga gaccaatcat aaacacagta aatcatgttt ctaaaacgga tgtaagtgta
    16621 cttttattgg gtgaatctgg aacaggaaaa agctcacttg ctagatatat acaccacaac
    16681 agcaatagat ctaatggccc atttataaca ataaattgtg caactatatc tccacaactt
    16741 cttgaatctg aactttttgg atatacttca ggtgctttta caggtgcaag tactaaaggt
    16801 aaagttgggc tcgtagaatt agctaatgga ggaactcttt ttttagatga aataggagat
    16861 ataccacaaa atctacaggc aaaatttttg caattaatac aggatagaac ttttactcca
    16921 gttgggagct taaaaaataa aaaggtcgat ataagaatta tatctgctac aaatgttgat
    16981 ttagtttcaa aagtaaaaga aaaaaagttt agagaagatt tatactatag attaaatgtt
    17041 atagaaataa aattgcctcc tcttagagaa agaagggata atctagtgga aattataaaa
    17101 tattatttta ataggtactc aagtgacttc aacctaaata aaactatttc taaggaagct
    17161 atggatgcta ttgcaaatta tagattccca ggcaatataa gagaattaca aaatataatt
    17221 caaaaaatct tgcttacttg tacagataat catataacaa tagatgactt accaaacatt
    17281 cttacaaaaa atatacatat taccaataat ggaaataaaa cacatatatc ccaaattaat
    17341 aaggttatta tatctgactc aaaatctact aattataaaa ataaaaattt tgacacttta
    17401 attaaagagt atgaaaaaaa tataattttg gatgcttatg aaaaatttgg tagttcttat
    17461 aaagtagcca aacaccttga aatctcacag tctaaagcca ataggttaat tagaaagtat
    17521 actaatactt aattttaaat ttgataaata aaaacttaac actatttaca tattgtaaat
    17581 ttggccattt actgttatta tgaatatggt tgaaattatt taaataaata ctgttgactt
    17641 agtttcatat atttaccatt aaacttttat cataaatatc atatcataat aatatattta
    17701 ataagtctaa taaactatac gaggtgtaaa tatgttaatg aatacccatt ttattatggc
    17761 aaaatcaata cttgataata tagatgaaaa taaaacattc tttataagcg aaaaaaattt
    17821 tatatatggc aatataaagc ctgatgcttt ttctaaatat aaattaaaaa aacattattt
    17881 agatgagtca tttaatatga ttgtttctaa aataaactat ctatgcagtc ttaatataga
    17941 tagtctttct aaatactttt cagtaagtag acttagtcag gaactaggag tcatatgtca
    18001 ttttttatgt gattttttct gtgtagctca cagtgaacgt tgggaattta agcatagctt
    18061 aaataaacat gttacttatg aaagagaact tggagcattt gcaaaagatg ttgatttatc
    18121 taaaattaaa tgtggtacta taaatagtag ttttgagaag ttttttacta aactttatag
    18181 tgattacaaa aagaaaactg attatatgaa tgatttaaaa ttttcagctt atacttgtaa
    18241 tagtgtcata aattatatac ttgactctat tttatctaat acaataaaat catatcatat
    18301 agcaaattgc ggttaactta agaattttta aacttatata aacttataat tgaatataat
    18361 taaaatgact gctctataga atataatttt atacttctct aggacagtca ttttttatac
    18421 taactattta tctccattat aacatctatg gcacttttta cactatctac tacataattt
    18481 gcactttgct ttacatcttc ccttgcctta gacattgcaa aactatattt aaatccttct
    18541 aacatgcaaa tatcatttgg agaatcccca atagtagcaa cttcatctgg acttacattt
    18601 aacgttttta ttacatgctc tatacttcct ctttttgaca cacttttagg aactatattt
    18661 aaagtatatg ttccagaaaa atatatttct aagacttcac taaactcact ttttagataa
    18721 agttctattc tggataactc ttccaaattt tcagaacata cgcctatatt tcctataaga
    18781 ttatcaaaac tacttctttt ttcaaaatct gggtcaacta taaagtcact agaataatgt
    18841 ctaaaagcag tggtatcact acccacaatt acatcaccct tatatttaaa ataaagttgt
    18901 gcatcacttg actcaaatct atcaatgact ttttttacta aattatcatc tatcgttctt
    18961 ttaaaaatta cattataatc tttatcatat ataaatgaac cattttcaca tacatagtat
    19021 ccattcatat ctaaactatc tttgataata ttatgtgctt gtttaaaaat tctacctgta
    19081 gcaacattaa actgtactcc ctttttttct atttcttcaa ttgctactat atcttctttt
    19141 gttatggttc cattttcata tagagttcca tctaaatcac aaaatatatg ttttatcata
    19201 aattaaaagc ctccaaaaac aattttatat tttactaata ctttaatcaa aataacttaa
    19261 agcttttcta attgtattct caattcatta agcaaatctc tagtagctct taatcttatc
    19321 tttcttctat ccccattaaa tatatttttc tttactattg tttttccatt tatatatatt
    19381 gcagtataaa ccagtcccac aggcttctct ttggttcctc caccaggtcc agctactcca
    19441 gttgtagata tacctatatt agctttaagt cctttagcaa tgccctcagc catttctata
    19501 gctgtttgct cacttactgc tccaaactct tccaaagttt ctctttttac tcctaatctt
    19561 ttcattttag aatcattaga atatgttaca caaccttcaa gaaatacaga ggatatacct
    19621 ggatagttta taagagatga agaaaccaaa cctccagtac aagattcagc cactgctatt
    19681 gttagatttt tttctacaag tagcttagaa acagcatctt ctaaagcagt ctccccttca
    19741 gatatggaaa tatctccttc agtatataca tatttaccaa ctctactttt tattttttct
    19801 tctactggtt ttattaattt aaaagcttct ctttcatttt cagcctttgc agttattctt
    19861 attgtaactt ctaattcttt tgcatataaa gcaactgttg gattagtctg ctcattaatt
    19921 atatcgagaa tttctaattc tagatttgac tcacctattc catataatct taaagtctta
    19981 gatactagca tttcatttgt gaattgttgt aagtaaggtt tgacactctc attaaacata
    20041 gctttcattt ctcttggagg tccaggcaat actattataa atttaccatc tttttttaaa
    20101 attgcccctg gagctgtacc attattattt tttagtacta tagcatcttt tggaaagtac
    20161 acttgtttca tattattttc ggccattttt ttccctgttt taacaaagaa agattccaaa
    20221 acctctagtg aaggtttatg tagttctaat ttctgaccaa agtattctgc agcagtttct
    20281 tttgtcatat catcaccagt tggcccaaga ccacctgtag taattacaaa atcacttctc
    20341 tttaagcttt catcaaaaca ttctaaaagt ctttgtttgt tatctccaac agtactctga
    20401 tggtatactt ctattcccaa tgatgcaagt tctttagcta aaaattgaga atttgtattt
    20461 actatatctc ccaataatat ttctgttcct acacttatta tttcagcttt caaaatttat
    20521 cactccttga tttatagcca ttaagactag tcttaagttc ataacaataa ttttagcaaa
    20581 aataataaca taaataaagt taaaaaatca tttaaacata tctttaaact agattattat
    20641 tctaaaacca cacataatat aaacttcgta tatagtggta ctttcatcct caactgttaa
    20701 ttcatataat taagtatgta aataaaaagt ttactttaaa ataataaaaa ttaaaatagg
    20761 agtgtataat atgaaaatag cagttataat gggtggaata tcatcagaga gagaagtttc
    20821 tttaaattca ggaaaagaga tatataataa ccttgataaa aataaatatg aagttgtaaa
    20881 ggtaataata gatgataaaa aagatatatt tacaaagata ccagaagata tagattttgc
    20941 aatacttgct ttacatggaa aatttggtga agatggatgt atacaatcaa tacttgagac
    21001 tatggatata ccatactctg gatgtggacc tctttgcagt gggatgtgta tggataaaaa
    21061 tataactaaa aaaatgctta gagattcaaa cctacctact gctccatggg ttttagtaaa
    21121 atcagttgat gaaatagact atgatgaaat agataatata ggttatccag tatttataaa
    21181 accaaactca ggaggttcaa gtgtagccac attctttatt cattctaagg atgaagttga
    21241 agaagcagtt agaaaaggtc tggaagttga tgaatttgta atgattgaaa aatatatacc
    21301 aggtggagaa tatacttcat tcatattaaa tggagaagtg ttccctacaa tatctataaa
    21361 atctgattca ggattctttg attatgaagc taaatactca gttgaaaaag gtgcaaagga
    21421 agaagttgtt tacttagatg aagaacttca aaaaagagta aacgaaattt ctgagacttg
    21481 ttggaaaatt tttaattgca aagcatatgt aagagttgat atgattataa gtgaaggtat
    21541 tccatatgtt cttgaactaa atactcttcc tggaatgact caaactagtt taattcctag
    21601 aagtgctgct gctagaggta ttaagtacag tgaactatta gataaactta tagaatactc
    21661 tttaaattag atgaaataat ttgaggtggt aatttgatat tttcaaatct aaaattaaat
    21721 gataatgaac caatttatat acaactaaaa aattatataa gtgatatgat atcaaaagga
    21781 ctaattccag acaatagtaa gctcccttct acaagggagc ttagtcagct tttacaagtt
    21841 agccgaaatt ctgtagtttt aacttatgaa gaattaaaat cagaaggatt aatctactct
    21901 atttcaggaa aaggtacatt tgttaaatca aagaataagt cttcaaatac tacatggtca
    21961 ttaaactggg attgtttaga gaatacatac tctaaaaaag ccaatgaatt ggacattata
    22021 aaaagtgaaa ttccttggag ctctgacctg atttccttta aaagtatttc tccagatgga
    22081 gatttattcg acatggaaga attaaaaaaa tcctttttaa atagaatttc actagaagga
    22141 cataaattac tcaactatgg atatgcacaa ggttataagc cacttattga ctatttacta
    22201 gaatatatga caaacaaagg tgctgatata agtaataaag atatactaat aacaaatgga
    22261 ttcacagaag gctttgatat tattatgtca tcttttaccc aagaaaaaga ctacataata
    22321 tgtgaaaatc ctactcataa tactgctata aaaattatga aatctcataa cctcaatatc
    22381 ttaggtgtag atataaatga agatggtttg gacttcaata tgctagaaga caatttagtt
    22441 aagtataaaa ataaaataaa gtttgcatac attacaccct cttatcacaa tcctacagga
    22501 attgtaatga ctcctgaaaa taggtacaaa ttctataatc ttatgaaaaa atacaatata
    22561 gcaattatag aagatggatt taatgaagaa ttactctaca atagttctca tatatttcct
    22621 atctgttccc tagataatat gaataatggg gtcgtatata ttggtagttt ttcaaaaatt
    22681 ttatttcctg gaatgagaat tggatggata tttgcagata aaaaagtaat caataagcta
    22741 gaaagtgtaa aaaggtgcag aaacatacat gtatcctttt tagaccaagg aattttattt
    22801 gattatttaa gtaatggagg ttttgaaaaa tacattaaaa aaatacgtaa attctatgga
    22861 gacaaattta actttgcata taaatgtata aaaaaatata taaaaacaga atatatcttg
    22921 ggtgatggtg gtttgcatat atttataaaa ctaaaaaata tagatactag agttttatta
    22981 gaaaaatgtt atgaaaaaaa tgttatattt atgcctggag acttattttt tacagataac
    23041 tctggttttg atactttaag gctcggattt tctaggttgt cttttgaaga cattgaaatt
    23101 ggaataaaaa taattggaga aactataaat gaaatgttct aggttaacta aatattgtta
    23161 gcctagttta tttttatgag gtataatata tatagtttat atgaatctaa tactggggga
    23221 taatatgagt aaaaagtcaa aacgaagaaa aattaataaa ttaaaattaa cgattgtaat
    23281 aactgtatta tttcttgctt tattatctat atatgagata ctgttctcta atcccaacaa
    23341 aaaaggtaat ataaagagtc aagaaactat gcaaaataaa aataatacaa cagatgattc
    23401 taaaaataat caaagctcta ccaaaaagca ggaagataat aatatcaaac ctactttttc
    23461 atattcttca ataccagata atataaaaaa taaaatgatt ggtaaatcta tgcctactga
    23521 tgaacctata agctttgata gtctatctta tttaaaactt acatattatg gatttgatga
    23581 aaaaactcat caaggagaaa tgatagtaaa cagtgaacta gctccagaag tagtggatat
    23641 ttttaaggaa ttatacgaaa aaaaatatcc aattgaaaaa attaagttaa tagatgacta
    23701 tgatgctgta gatgaaaaat ctatgtctga taataatacc tcatcatttt gttatagaac
    23761 tatagctggt acaaatgtag tttcaaatca tggtaaagga cgtgctatag atataaaccc
    23821 attacagaat cctcaagttt ctggaaatga tgttacacct aaagtaagta cagtttatgc
    23881 tgataggtct agcacaaaat ttggaatgat aaaaaaaggt gatgattgtt ataatgcttt
    23941 tgtaagcaga ggttggagtt ggggtggcta ttggaaaaac ccagattatc aacattttga
    24001 aaaataatag attagaaata aaggtgaatt atatgaattt aatgacattg gaaaatataa
    24061 gtaaaagcta ttctgaaaaa aaattactag aaaatatatc tcttggaata aatgaagggg
    24121 aaaaaatagg atttattggt gtaaatggta ctggtaaatc taccttactc aaaattattg
    24181 caggagttga agaaagtgag actggtaata taacaaaaac taatggtatt aggatagaat
    24241 atctacctca aaatccaact tacaatgaaa attcaactgt acttgaacaa gtatttaatg
    24301 gaacttctga agaattaaag ctacttggtg aatatcaaga aatcctagaa aaacttaatt
    24361 caaactttac agaggaatta aataaaaaat tattatcagt acacgaaaaa atagatgcct
    24421 taaatctttg ggatttagaa agtgaagcta agtcagtact tacaaagctt ggtataaatg
    24481 actttaatca aaaaatagca gaactttctg gtgggcaaag aaagagagtc tctctggcat
    24541 cagcccttat tacaccttgt gagtttttga tactagatga gcctacaaac catctagaca
    24601 atgatactat agattggctt gaggaatatc ttaattccag aaaaggttca ttgcttatga
    24661 taactcatga tagatacttt ttagaccgtg ttacaaatag aattattgaa ctggacaaag
    24721 gtagattatt cagttatgat gggaattatt caatattttt ggaaaagaaa atggaaagac
    24781 tttcgctaga agcaagtatt gaagataaaa gacaaaattt aataagaaca gagcttgcgt
    24841 gggtaagacg aggagctcag gctcgtagca ctaaacaaaa agctcgttta caaagatttg
    24901 atgaacttat aaatagagat tcttttaaac ctgatgaaaa tctcgatata tctgttgcat
    24961 caagtagact tggaaataaa ataatagaaa tacacaatat atctaaatca tttgaagaaa
    25021 atactgttat agataattta gaatacactt taactcgtac agatagaatt ggtataatag
    25081 gcaaaaatgg tatgggtaaa tctaccctta taaatatact taatggagaa atagagcctg
    25141 atagtggata tatttcaatt ggagaaacag ttaaaatagg ttgtttttct caagacgact
    25201 ctcatatgaa tattgatatg agggctatag actatgtaaa agaagctagt gactatatag
    25261 aaacttcaga tggtactagg attacagctt ctcaaatgtg tgaaagattc ctttttaatg
    25321 gtactatgca atatactttg ataggtaaat tatctggtgg tgaaagaaga agactacatc
    25381 ttcttaaaat ccttatgaca gctcctaatg tgcttctttt agatgaacct acaaatgatt
    25441 tagatattga aacgcttaaa atattagaag aatacctaga cgaatttaaa ggtgtagtag
    25501 ttacagtatc acatgataga tatttcttag atagaatttg taataaaata tttgcatatg
    25561 aaggtaatgg aaaaattcat atctatacag gtaattacag tgattatctt atttatagag
    25621 agattcaagg aattgaattt gaagaatcta aaagggaatc agttaaaaaa gatgactcta
    25681 ctaccccaaa aaaagaaaaa cctaaaaatg ataaaaagct taagttctca tataatgaac
    25741 aaagggagtt tgaaaatatt gactctgata tagaaaaact cgaatctaaa attgcaacac
    25801 ttgatgaaag tactgcaaaa ttttcaactg attttactaa actccaagaa attttagatg
    25861 agaaatctaa actagaaaaa gaacttgaat acaaatatga aagatgggaa tatttaaata
    25921 atctagctga tgaaatagct aataataagt aatattaaaa taatcttaag tttaataagt
    25981 tttgctttaa atctgtaatt tataaatatt ttaaaggaag tgtctcaaaa tgaacttttt
    26041 agttttatga gacactcttt tttatgagaa atcaaatata ttttcatcat ttcaacaata
    26101 caaaagaggc ttatctctat tttgagacag cctctttcat aattaccttc taatttatat
    26161 gctctaatat atctataata attcttatta tatctatata tccagtcttt caatatagtg
    26221 acaattaact tcaatatgat ttaaaaatac taacaacctt tcataaagtg gatgagattc
    26281 ttctccatat ttagcttcta ggttcttgcc tatttctcta acagtccttt gaccatcaat
    26341 ttgtaaaaaa acaaaactgg aatattcatc tagttctatt tttttgtatt taggtattct
    26401 agcttttaac tttctaaaaa acttttgaat tttatggtcc tgtttttcaa gtatagtaac
    26461 aacacgattt tcagctactt catattcaag tccatcagta attttaaata caatatctaa
    26521 aacatcatta ctcttgctca ttatttttta ctttagataa aacaataggt aatgctgtaa
    26581 gcacaactaa aactactaat aaagcaattg ccattgaatt tgttgcagca aatccacttg
    26641 gtacctttgg agttacaact ccagttactt gtaatattat acctattaaa ccaatgatag
    26701 aaccaccagc aacaagacca gaagataaac ttataccatt agaaacttta acttcttttt
    26761 ctttttcagt tttagatact aattcaacaa ataaacgaat taatgctcca actaatatta
    26821 tagaagtagt tgcaattggt aaatagaatc ctatagctat agtcattatt ggtaaattta
    26881 atgcatatag aactattgcc ataaatactc caacaataat cataacccaa ggtaaactac
    26941 ctgacataat accagaagtt aatgttgaca ttaagtttgc ttgtggtaat gcaaattgta
    27001 cattatcacc agttgctcta agttggtcag aaagtaataa aattactcct acaacaacta
    27061 taacaccaac tatacttgca attgtaaagt aacgttgcat ttcgtttttg ctaccaccaa
    27121 taatataagt tactttttga gattgagtat aacctccagc tatagcaata gcaacaacta
    27181 taaatgaacc aaataaaagt aatgatttat tagcttctaa atcagtccat cccattataa
    27241 caaacactaa tgttacaata actagagaag ctatagtcat accagaaact ggaagatttg
    27301 atgttccgat tgttcctgtt aaacgaccag ctactatgac aaataataaa gataataaaa
    27361 gagatatgat agctccaata attgccataa caatgttacc agaaattaag aatgctgcta
    27421 aaaatccaat aactactcca cctaataaaa gtatcatttg tatagatgaa ccttcttctc
    27481 cttctccagc acttgattta gctttaagtg tttcttttat agaagcgatt atagttggta
    27541 taagttttat tgcaccaata atacctccac aaagcatcat accagcacct atatatttta
    27601 cataactact agatattgct ccaacatcca tttggttaag aggcattgca ggattattcc
    27661 ataccatagc tccatcttta gccatatctg taaagtatcc tattaaaggt gctataccaa
    27721 agtttgataa aatacttcct gcaaacattg ttaaagaaac ttcaagccct actataaatc
    27781 caattcctaa aagtagagga tttacttcaa tatcaaattt ccatttgtag aatttgcttc
    27841 ctacaagact cattacattg tttgctacat ttaagaatga accagttaat acagtaataa
    27901 atccacttat tacaaatcca attcccatgt acttaattga atctccacca gcctctgaag
    27961 caacaagtgt ctcagatata gccattgatt ctgggtacat aagtttacca tgttcttcaa
    28021 ctattagata gttgtgaact atagcagcaa ttcctatacc aaataaaact ccaccaactc
    28081 caacagctaa gccttctaag aatgtaattt ggcttccaat taatataact gctggtaata
    28141 cgaaaataaa tccacttgca acagattctc caccacttga cataccttgg attaagtttt
    28201 taccaagaat accctttgaa cgagcaaatg ctccaacaaa agcagaacct attatagctc
    28261 ctggaatacc tgcggcaact gtaagaccgg ctttcattcc agagtaagtt gtagatgcgg
    28321 caaaaatggc agctaaaata ataccgataa tcagtacagc tacatttcca ccggttctgg
    28381 acttatctgt gatatatgga acgtaatctt ttccactaac ctcaccataa gcacccttag
    28441 gtaatttttt gttcataaaa ttttcacccc ttttcaattt gtatatatta taacatatat
    28501 acatataaaa cttaactttt tattatttta caaatagcga gtcaaaacta ctaaaattta
    28561 accctatatt attaatttct acttttagat atttttatgc taattttctt tttatttttc
    28621 aattctact
//
LOCUS       DAYAOO010000050        28273 bp    DNA     linear   BCT 12-OCT-2024
DEFINITION  TPA_asm: Clostridioides difficile isolate ST8-SSI-h139-18
            SAMN40601845-rid21577343.denovo.050, whole genome shotgun sequence.
ACCESSION   DAYAOO010000050 DAYAOO010000000
VERSION     DAYAOO010000050.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN40601845
            Sequence Read Archive: SRR28438827
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 28273)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 28273)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-MAY-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-MAY-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002157583.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002157583.1
            Genome Coverage       :: 163x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/11/2024 16:19:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 4,038
            CDSs (total)                      :: 3,963
            Genes (coding)                    :: 3,930
            CDSs (with protein)               :: 3,930
            Genes (RNA)                       :: 75
            rRNAs                             :: 6, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 60
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 33
            CDSs (without protein)            :: 33
            Pseudo Genes (ambiguous residues) :: 0 of 33
            Pseudo Genes (frameshifted)       :: 7 of 33
            Pseudo Genes (incomplete)         :: 25 of 33
            Pseudo Genes (internal stop)      :: 11 of 33
            Pseudo Genes (multiple problems)  :: 8 of 33
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..28273
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN40601845-rid21577343.denovo.050"
                     /isolate="ST8-SSI-h139-18"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Denmark"
                     /collection_date="2018"
                     /collected_by="Statens Serum Institute"
     gene            149..853
                     /locus_tag="ACGI5H_002385"
     CDS             149..853
                     /locus_tag="ACGI5H_002385"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888771.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000156 - phosphorelay response regulator
                     activity [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HFG9698086.1"
                     /translation="MSKLIYIADDEDNIRNLVKTFLKNEGHDVMDFKTGDELLEQFNI
                     KECDLVILDIMMPGSSGFEVCTKLREKSTVPIIMLTARDTDIDYITGITLGSDDYFTK
                     PFSPMSLVMRVKSIFRRIEFEKKQNYDKYSNSIDMELKFGDVIINKKNKIVTSKNVNI
                     DLTPNEYNLLTYLFENIDRAVSRDELLNKIWGYDIEVETRAADDTVKRLRKKILNTNI
                     LIETVWGFGFRLKEKS"
     gene            855..2342
                     /locus_tag="ACGI5H_002386"
     CDS             855..2342
                     /locus_tag="ACGI5H_002386"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003432175.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HFG9698087.1"
                     /translation="MKNGNDKNRIGKIKSKFKLKFSKKNISIKTRILLSILCLIIIVF
                     MIILVSFNVFLDTYIKTTANEELTKSTEIVEHMDSNFRPIKPPQDDGKLPPKVLSNFM
                     RNVQDKVRMAETQSDADAMVVDSKYNLIFPTREDDFLKNVDEMELIRECIQNEKLDLN
                     SDENTRISTRNKDYYISTVKITSIYGEQDKYLILFIDISKTLNLAQKINIVLISVMCF
                     AGILAIFTAVILSEKIAKPIKELCEFAKKMGQGDFKRTYFDFSDKELVELSTVMNKSA
                     EYLDKYDNEQKIFFQNASHELRTPLMSIKGYAEAIKYNVIDSKHASDIILEESDRLSD
                     MVEDLLYISKIDNITKDFELVECDLREVLSNCGARQNVRAINKGIKFIYEFDEEMVLF
                     ECDEKNISKAFMNLIENALRYAKSEIKIVCKYNQKNIVVIIEDDGIGIKKEDLPHVFE
                     RFYKGVGGNHGIGLSIVKSIVNKHGGRIYVENGKKGAKFTILFKL"
     gene            2547..4160
                     /locus_tag="ACGI5H_002387"
     CDS             2547..4160
                     /locus_tag="ACGI5H_002387"
                     /EC_number="2.7.7.65"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437032.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0009975 - cyclase activity [Evidence IEA];
                     GO_process: GO:0009966 - regulation of signal transduction
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="diguanylate cyclase"
                     /protein_id="HFG9698088.1"
                     /translation="MKEQLIFNITNLVTVVFEAFVIHMFLSDFLGQKEGYIKVVRYAK
                     LGFIICLGFCNLITLNPKITMPLIFILIFSTSFLYKGNLKTRLFTTVLLSIFFILSEI
                     VVTSIFVLFVKEGFEIMLENNSIRVLATILSKIVFLLTCKIICLFKKDVHLDMPIKYW
                     LPLFLIPIFSLFLSVSIFDVSKFFSLESLKFLSLISSVGILYINFIVFYLFKFIIDKT
                     KLSMKYELLEKEIIHKEELRLSNECYKIIVEQTDSVVFEWNIKENKSFVSQAWTEKFG
                     YNNACKNIFKEIKDKDLVHSEDKAIFEGFLESIKKKNMHNQAVYRLKKSNGEYIWCRT
                     SITSIYNDENELLRVVGVIVDVDSDIKKYEELRTRAESDSLTNIYNKGTFEKLVEETI
                     VMNTGDKKDALFIIDLDDFKEINDNFGHPFGDFVLKTFADKIQTSFGSKDLVGRIGGD
                     EFVVYMQDYVTEVNLHKKAKELNRVLSDNYTDLSFSFDASVSIGIARYPQDGTSFFEL
                     FKNADRALYSIKASGKNSYCLFEEELYVQ"
     gene            complement(4523..5353)
                     /locus_tag="ACGI5H_002388"
     CDS             complement(4523..5353)
                     /locus_tag="ACGI5H_002388"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728696.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HFG9698089.1"
                     /translation="MSQVSKNYFTTGEFAKICGINKKTLFHYDDIGLFSPELKKENGY
                     RYYSYHQLSIFGIISSLREVKMPLKEIKAYIDKRTPNLLIELLEKKTIDIKNEIEKLN
                     NIQALMESTISFTKSACNIDANTITLKEHEEEYLVKTPVTYKEQFLGDEEENFLYECI
                     NFMDNYELSDYGTIGSIIKGEDIINKDFESYSYLFTKVNKEYKKYPVSIKPKGLYVTA
                     YHKGSYETIYKAYEKLLNFFNQNNLRIGDFVYEEYLLYDISVRDSNEYLTQISAEVKM
                     "
     gene            5426..7153
                     /locus_tag="ACGI5H_002389"
     CDS             5426..7153
                     /locus_tag="ACGI5H_002389"
                     /EC_number="7.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888775.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HFG9698090.1"
                     /translation="MKKLIHFLKPYRVLIVVVLIFTFLQTLGTLYIPTLTANIVNNGV
                     VKGDIDYIVKTGLMMMIVAGITALSAVLVCKVSANLSSGFCRDIREAVFIKSQDLSIN
                     DFNNIGTASMITRSTSDITLIGQSVFMFIQLVLPAPIITVSGLFLAYSIDKAMTIIIV
                     VVMFLFMLSAFLVGKKLIKLFKMMQIKMDNMNRVLREVVTGVRVIRAFNRSRFEKKRF
                     DRTAIDYSETAISINKIFAVLMPIVMLIMNLGIVSIIWFGGMRVSNGNMEIGHIMALV
                     EYCILILFYLIMGVMVFMYIPRAGACADRVNQILDIEPEIVDGNGHKDTVSERGHLVF
                     KNVTFSYAQSEEPVLNNITFEAKSGEVTAIIGSTGSGKSTIANIIPRFFEIQSGEISI
                     NGQDIKKIPQKELRDKIGFVPQKAFLFSGTIEENIRYGKEDASIEEVKHAASIAQADE
                     FIYDMEDKYDSFVAQGGNNLSGGQKQRISIARALVRKPEVYVFDDSFSALDFKTDKRL
                     RKALKNEIKDSSAIIIAQRISTIMDANQIIVLNDGKIVGIGKHKDLLENCEVYKQIAD
                     SQLSKEELA"
     gene            7190..9052
                     /locus_tag="ACGI5H_002390"
     CDS             7190..9052
                     /locus_tag="ACGI5H_002390"
                     /EC_number="7.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003432166.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HFG9698091.1"
                     /translation="MSEKRIDEQDIEVLSFEDGMSAEKAKDAKKTTKRLLKYMAKQKF
                     KILIIFISVLISSALTVLAPMVMGKAIDQLFNGIKTAVQTGTKFSVNFSTMGGIVSIL
                     LGLYLISAVFIYIQQYIMSGVAQNLVLSMRKDLSDKLNKLPLKYYDSHKKGETLSIVT
                     NDLEKVADSLQEGLMQLITAVVTVVGSIVMMISISVPLTIVSAITLLVSLGITVVIAR
                     KSQERFSENQKALGELNSNIEEIFTGQIVVKAFSKEKDTIRNFKILNQNLYNASRKAQ
                     FSSYAISPIIRFINLIGYVIIAVVGGIFASTGAMTLGSIQAFIQYVNQASEPTTEISY
                     IVNMLQAAIASAERVFTVMDEVEEIKDEESSKVISMPKGKVQFEHVKFGYSDDFILMK
                     DININLNAGDKIAIVGPTGAGKTTLVNLLMRFYEIQGGRITIDGVNIKDLKRGELRTM
                     FGMVLQDTWLFNGSIKENIAYSKSDATMDEIVRAAKSARVDHFIRTLPQGYDTILTED
                     ASNLSQGQKQLLTIARAILSDPSVLILDEATSSVDTRTEVEIQKAMNNLMKGRTSFVI
                     AHRLSTIRDADLILVMKEGTIIEQGSHKELIEKKGFYEELYNSQFTSEYDEDVV"
     gene            9385..10074
                     /locus_tag="ACGI5H_002391"
     CDS             9385..10074
                     /locus_tag="ACGI5H_002391"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888776.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polyphosphate polymerase domain-containing
                     protein"
                     /protein_id="HFG9698092.1"
                     /translation="MNKKLNYRFEMKHKITEADVLALKSRLYPIMKKDENASKDGKYL
                     IRSLYFDTPEDKALLDKLNGVAIREKFRIRFYNNDCSYIRLEKKIKHYNMTSKLSTNL
                     TKKEVINILNNDIEFLKESTNCLLREFYLKLKCERLEAKSIVDYNREAFIYPVGNVRV
                     TIDSDIKTSVNSVDLFNKDLPTISVIDENMTVLEVKYDEFIPDFIKDLIQINKTTSTA
                     VSKYASSRLYI"
     gene            10191..10865
                     /locus_tag="ACGI5H_002392"
     CDS             10191..10865
                     /locus_tag="ACGI5H_002392"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895980.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4956 domain-containing protein"
                     /protein_id="HFG9698093.1"
                     /translation="MTFNDIFKSSFIENVSGFSFVDSALALGSAFLVGLFIYMVYKKT
                     YMGIMYSRPFNVSLVALTMLTTFVILAVTSNVVLSLGMVGALSIVRFRTAIKDPMDLV
                     FLFWSLGSGIVLGAGLIPLAVMGSIIMGLILIFFSNKTISETPYILMVNCNNEDSEDI
                     ATDKIKKVFTKYQIKSKSVTPEKGIELVFEVRMKDGETSLINDLSQVDGVTNAVLVSY
                     NGDYVA"
     gene            10882..12789
                     /locus_tag="ACGI5H_002393"
     CDS             10882..12789
                     /locus_tag="ACGI5H_002393"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437021.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CotH kinase family protein"
                     /protein_id="HFG9698094.1"
                     /translation="MKDKKFTLLISIMIIFLCAVVGVYSTSSNKSADLYSDVYIEKYF
                     NRDKVMEVNIEIDESDLKDMNENAIKEEFKVAKVTVDGDTYGNVGIRTKGNSSLISVA
                     NSDSDRYSYKINFDKYNTSQSMEGLTQLNLNNCYSDPSYMREFLTYSICEEMGLATPE
                     FAYAKVSINGEYHGLYLAVEGLKESYLENNFGNVTGDLYKSDEGSSLQYKGDDPESYS
                     NLIVESDKKTADWSKITKLLKSLDTGEDIEKYLDVDSVLKNIAINTALLNLDSYQGSF
                     AHNYYLYEQDGVFSMLPWDFNMSFGGFSGFGGGSQSIAIDEPTTGNLEDRPLISSLLK
                     NETYKTKYHKYLEEIVTKYLDSDYLENMTTKLHDMIASYVKEDPTAFYTYEEFEKNIT
                     SSIEDSSDNKGFGNKGFDNNNSNNSDSNNNSNSENKRSGNQSDEKEVNAELTSSVVKA
                     NTDNETKNKTTNDSESKNNTDKDKSGNDNNQKLEGPMGKGGKSIPGVLEVAEDMSKTI
                     KSQLSGETSSTKQNSGDESSSGIKGSEKFDEDMSGMPEPPEGMDGKMPPGMGNMDKGD
                     MNGKNGNMNMDRNQDNPREAGGFGNRGGGSVSKTTTYFKLILGGASMIIMSIMLVGVS
                     RVKRRRFIKSK"
     gene            13242..13931
                     /locus_tag="ACGI5H_002394"
     CDS             13242..13931
                     /locus_tag="ACGI5H_002394"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HFG9698095.1"
                     /translation="MLQKVLWKFLKLVVGLFICSVGIVLTINCNLGLSPWDVFHQGLS
                     NHIGITIGTASIIVGSIVVIADVVLGENVGWGTVFNMLLIGFFMDLLLYSNLIPEADS
                     LFVGIIMLILGLVLLSVGMVFYMGSGLGSGPRDGLMVAIQKKTGKSLKLIRGTIEVGA
                     LIVGFLLGGKVGIGTIISAFGLGYFTQMVFGLFKLDCSKIKHRFIVDDIKFIKVYMSG
                     EKKAAVQNIVK"
     gene            14367..14906
                     /locus_tag="ACGI5H_002395"
     CDS             14367..14906
                     /locus_tag="ACGI5H_002395"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007286148.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="XRE family transcriptional regulator"
                     /protein_id="HFG9698096.1"
                     /translation="MDIGEKIKRLRTEKQLTQEELANRCELSKGFISQLENNLTSPSI
                     ATLIDILEILGTNLREFFNEIDDERISFTKEDMFETEDEDLKYKLKWLIPNSQKNEME
                     PIIITLYPGGQYKEEKPHEGEEFGYVLAGSIYVHIGEKKNKVKKGESFYFRPKANHYI
                     SNEGKTTAKVIWVSTPPSF"
     gene            14925..15968
                     /gene="potA"
                     /locus_tag="ACGI5H_002396"
     CDS             14925..15968
                     /gene="potA"
                     /locus_tag="ACGI5H_002396"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437017.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:1902047 - polyamine transmembrane transport
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="spermidine/putrescine ABC transporter
                     ATP-binding protein"
                     /protein_id="HFG9698097.1"
                     /translation="MVENIIELRDISKHYEELTVLDNFNLDIKKNEFLTLLGPSGCGK
                     TTTLKIIAGFEYADDGKVLFEGKEINNLPPYERQVNTVFQKYALFPHMDVYENVAFGL
                     KIKKTPKDVIDAKVKEVLKLVALEGFERRQVESLSGGQQQRIAIARALVNEPKVLLLD
                     EPLGALDLKLRQEMQIELKRIQKKLGITFVFVTHDQEEALTMSDTIVVMYKGKIQQMG
                     TPQDIYNEPKNSFVAKFIGESNIFDGIMIEDYKVNFCNRDFECVDKGFEKNENIEVVI
                     RPEDIKMVKPEEGMLKGKVTSTVFKGVHYEIELNENGRLWILHNTKNAEVGTELGMDI
                     YPEDIHIMRKENN"
     gene            15970..16806
                     /locus_tag="ACGI5H_002397"
     CDS             15970..16806
                     /locus_tag="ACGI5H_002397"
                     /EC_number="7.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003432157.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HFG9698098.1"
                     /translation="MKRKSFLAYPYVVWSAIFVIIPLILVVFFSFTKESGGGYAFTLE
                     NYKEVIDPIYMKVFGRSILLAGGATLICLIVGYPVAYIISKARVSRRGSLILLFILPM
                     WMNFLLRTYAWVAILGKNGLLNTFLGWFGIQPLAILYTNFAILLGMVYNFLPFMVLPI
                     YTALSKMDNDLINAAHDLGANNMTVFRKIIFPLSLPGVMSGITMVFMPAVTTFAISRL
                     LGGGKIMLVGDLIEQQFTVVGDWNFGSAISIFMMIVILISMSIMSKFGDESDKEGGGL
                     LF"
     gene            16911..17585
                     /locus_tag="ACGI5H_002398"
     CDS             16911..17585
                     /locus_tag="ACGI5H_002398"
                     /EC_number="7.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437015.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HFG9698099.1"
                     /translation="MARWNGFTWKWYGQLLQNESIMSALYYTIVIAILASVISTIVGT
                     ISAIGIHKMRGKSKKLILNVNYLPILNTEIVTAVALMSLFVFVKMEFGFTTMLLAHIM
                     FCLPYVILSVLPKMKQLPDNIEDAAMDLGATPIYALRKVILPQIKPGIVSGFLIAFTM
                     SIDDFIISFFNAGNGVSNLSIEIYGMARRGIKPEINALSTIMFAVVLGLLLLANKKES
                     IVRGIK"
     gene            17585..18637
                     /locus_tag="ACGI5H_002399"
     CDS             17585..18637
                     /locus_tag="ACGI5H_002399"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728693.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="spermidine/putrescine ABC transporter
                     substrate-binding protein"
                     /protein_id="HFG9698100.1"
                     /translation="MIKFKKAISLIAVGMMTVTLFTGCNKATDSTKVLNVYNVGDYID
                     ESLIDKFEKETGIDVQYSTYDTNEMMYQKVKSGSTHYDLVFPSDYMVEKMKNEGLLEK
                     LDFKNIPNMKYLDKSFLNPVYDKTNEYSVAYMWGTLGILYNKKEVKDPMDSWNILWNP
                     KYKGNIMMFDSVRDTIGITLKKLGYSMNSVNPKEINEAKNLLMKQKDLVLAYVNDEGK
                     DRLLGGEVAMGMLYSGDAVTLMEQNPDLDYAIPKEGTNKWVDAMCVPTTAQNKKEAEL
                     FINFLLDPENAKVNAEYIGYSTPNTGALKLLDPEITQNPVAYPSKEVLDKCETFEDIG
                     ENIKLYDKAWIELKSK"
     gene            18867..19715
                     /locus_tag="ACGI5H_002400"
     CDS             18867..19715
                     /locus_tag="ACGI5H_002400"
                     /EC_number="2.7.7.65"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902229.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diguanylate cyclase"
                     /protein_id="HFG9698101.1"
                     /translation="MNRINKKIDLLILALLVFIFLIVGIVILSIRTENKLNVFIMLAI
                     IFFIIMLTYLSNSVVGLITSSIIIFMYTSYILYNNITHNMDVEFISYMWIIATPVSSI
                     IMGNLNKSINELQNTNKKLSEQYKELVTIDSETGLRNLKIFYNDVNMEISKSIRHNTD
                     FSLMIVKLPYYGNLQTIFGENKTNKIVKYIGSNIIECTRNEDIIYSLQKDMIGILMPN
                     TSLEGSKVVKDRIKKRIKELNLDLNNRGKYVNIDVKIAFLQYKSSFGDSINFKNIVEE
                     ELQYDV"
     gene            19705..21369
                     /locus_tag="ACGI5H_002401"
     CDS             19705..21369
                     /locus_tag="ACGI5H_002401"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437010.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2334 domain-containing protein"
                     /protein_id="HFG9698102.1"
                     /translation="MMFKIFNKSLLKLVVVLSIVLTISNFSLSSYASEITSSTDKVLI
                     IYDSKKETAYNRDILNIMRTLLGRFSSDIELLKLSNYDGEINKNYYSHIFILGINENS
                     YNNDKNTKNLISSLNLYKGTICWLGYGIENLLEHKKYNLDYVGKTNNIVSVNYRGKSY
                     NLDEHYVFNIVESKDTSNKVIGSINDTLNKYPYIINDKNLFYVSKLDLDGVLFYIFCD
                     SLNDIFNIKTFDKGRIFVRIEDVHAFREPKNLVEIADYLSSKNIPFTIALIPAYVNPK
                     NHKVITLSESPEIVKAIKYMQDKGGTVILHGYTHQYKKEEVSGEGYEFWDGKKDEPLK
                     ENMKIFVKDRVLNGLRVCIENGIYPLAFEAPHYAMESEGYKELKKYFSTYIGQHQNND
                     KKFSTNTYPYIIRDTEEFNIFIPENLGYIDPEDKFTFQNIKENLDKLSIVRGFSGGFF
                     FHSYLNIEYLKNTIEYLEKQNIEFMNLRDFNNWVKVDEIQIRNNGDEIIVNYDKDLDE
                     LTKSDTRFKSISNISKVLIFIVSISVLIFVIIFIYFKRIDKKKFLK"
     gene            21418..22674
                     /locus_tag="ACGI5H_002402"
     CDS             21418..22674
                     /locus_tag="ACGI5H_002402"
                     /EC_number="2.4.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895988.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016757 - glycosyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HFG9698103.1"
                     /translation="MRDLNVSEYLFVFSLFSIWSLLLINIILAMGGYIFYFKNFDKEI
                     KEIDEYPMISILVPAHNEAKVIGRTVESLLLLNYPKSKMELIVINDNSSDNSKEILEN
                     IKDRYNNYNFTIINTDSLTGGKGKSNALNIGYTISKGDFIAVYDADNTPDKNALRYLV
                     QTIVMNDELGAVIGKFRTRNKNKNLLTKFINIETLSFQWMSQAGRWQLFNLCTIPGTN
                     FILRRSIIEEIGGWDSKAIAEDTEISFRIYKLGYKIKLVPQSITWEQEPETVKVWIKQ
                     RTRWAKGNIYVLMKYIKNIFKQGRNKIVFDIAYFFSVYFLFLTSVIISDILFVLSISK
                     LVEISIPINFFLIWILSYLLFIIEVSISLTIEKGEATIENIFIVAIMYFTYSQLWLFV
                     AIKGMIEYLKDIIFKREVKWYKTERF"
     gene            22697..24778
                     /locus_tag="ACGI5H_002403"
     CDS             22697..24778
                     /locus_tag="ACGI5H_002403"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728691.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_process: GO:0006011 - UDP-glucose metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cellulose biosynthesis cyclic di-GMP-binding
                     regulatory protein BcsB"
                     /protein_id="HFG9698104.1"
                     /translation="MKKFIISIISLVLFFSNISLIYKVNADETKVKNYKFERDITIDG
                     VIGSNSTFFEVNKNWDIEEVLLHLNFSKSQILNGDVSSLTVLINNVPIKSIKLNAKTN
                     YKNTLEVLVPKDYIIQGYNEIKIKTYKTISDKICQDDSNTGNWMVIHKESYISIRYKQ
                     KKVENSINEYPYPYAEIENNHKLDTTIVVPDNMTRGETTAVFNLASAFGKITKNDDLK
                     LDVKLYSEMKNWSDDNIIYIGKPENTAEEILDILSIKEQTLLSSNCIIKQVDSPYNKN
                     KKMMVVIGSNEDDLIKASNLLIENRLSNQVLSSSVLVNKETNIKINREQKLNLGHLTL
                     KDLGYSDFLLEGAFNQQALFDVKIPTGKVLDDGSKIILNLRYSDNLDFEKSLVTVSIN
                     DVIVGSKKLDRSHSNNDKLELKIPKDIDNKNYYQVKLTFNLSIKNSNCVTRESNNPWA
                     YVSNNSYLALSTKENETLSFENYPYPFVRDDEFNDLTVIMPDYSGSQAMTWMFRLGVT
                     LGANINSHNGNINVIRGKEFSDKYKDTNIVVFGVPHNNSVIKMLNNNLNIKFDKNYSN
                     FISNDKISFIDDYGKNISTIQLIKSPYNNQKNIMVISSMNEKNLYLGMDYLLNKSKVN
                     DLKGDTLIIDEYGEVEDLAYNLKSKKEVKDSSWNMSINKTTKVFLMISFITIIIVMIL
                     SMLYIKKYKRR"
     gene            24815..25900
                     /locus_tag="ACGI5H_002404"
     CDS             24815..25900
                     /locus_tag="ACGI5H_002404"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888788.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydrolase"
                     /protein_id="HFG9698105.1"
                     /translation="MRKYMNEFKLKRSILISLIILIFIFIVYFVSIELKDRSLVNNQY
                     KGKIKSANLSVDYEINQVMKDIDKLGLNTVNVPIIINVESINSDIMSIDNNSKEKAIK
                     LIKKLNKKGISTILEAYPWIENGKLYETDWNPINKKRFFYTWQNAILNELIIDVANPL
                     DVNVLNIGSNFVHLEEYQQNWGEIIDFVQSKFDGLVTYRTNWWYTKKDDLSSKLFYEQ
                     KLNNNFFDKLDFISIAAYFELSNKPVNTVDELISALHSSTVNNRGQNIKQEIYNLYKA
                     HRKPIFFGELGFSNRESASSQPWNHTPSKAVNGEEQARCFEAYKKVFENEDWINGFSV
                     FCVGKIDDEKNFYPSKESIKVIKSWYE"
     gene            25954..27078
                     /gene="wecB"
                     /locus_tag="ACGI5H_002405"
     CDS             25954..27078
                     /gene="wecB"
                     /locus_tag="ACGI5H_002405"
                     /EC_number="5.1.3.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888791.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008761 - UDP-N-acetylglucosamine
                     2-epimerase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="non-hydrolyzing UDP-N-acetylglucosamine
                     2-epimerase"
                     /protein_id="HFG9698106.1"
                     /translation="MNDIKVMTVFGTRPEAIKVAPLIKELEKRENIKSIVCVTAQHRE
                     MLDQVIETFNINVDYDLDIMEKGQSLNDITCKILNKLPLILNKENPNIILVHGDTTTT
                     LATSLTAFYNKTLVGHIEAGLRTYDKYSPFPEELNRQLTGIIADMHFAPTNLARKNLI
                     SEGKPNNNIFVTGNTAIDALKMTIKENYNHPIIDEIGNDRMILLTSHRRENLGKPMKN
                     IFRAIKRIVDDFEDVQIVYPIHLNPKIRTIADEIFGKFPEKIHIIEPLDVADFHNFLN
                     KSYMIMTDSGGIQEEAPSLGKPVLVLRDKTERTEGIEAKTLKLVGTNEDRIYNSVSDL
                     LINKDNYVQMSKASNPYGDGNASKYIVDIIIKKFNCKYLN"
     gene            27156..28130
                     /locus_tag="ACGI5H_002406"
     CDS             27156..28130
                     /locus_tag="ACGI5H_002406"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861074.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004040 - amidase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glucosaminidase domain-containing protein"
                     /protein_id="HFG9698107.1"
                     /translation="MARKLIKNLGKSKSVKRVKLLFKKIFITVFIVASIVAIFNITKY
                     FEELYKVRDLKSTKIEYYMDVADEAGDGKVQLSWKALLAIDMVIHDEDLSNIKKKDTL
                     DIGEKFIVEDKNGKGEKVYKVKKFNKVLSELKFDSSQKSRARKYMKDLEYTYLGNKQL
                     DSSDEKIKFIKKLEDSAIREYIDYGILPSITIGQAILESGWGNSKLTKQSNNLFGIKA
                     DKAWKGKSVEISTSEHYNEKIVASFRSYNSLQDSVKDHSLFLINNKRYRKHGLFEAKD
                     YISQAQALENAGYSTAEDKKGNRIYAELLIDVIRSYNLQLIDNKVETK"
BASE COUNT        11253 a         2786 c         4862 g         9372 t
ORIGIN      
        1 acaattttaa aactaatgta ctataaaaag ctggtataat ttaaatatag taaaaaataa
       61 gatttatctt atctattggg atttaattat ttaatcaata tatttatacc atttaattta
      121 aataaaaagt ctattaagga gtgagcttat gagtaagtta atttatatag cagatgatga
      181 agataatata agaaatttgg taaagacatt cttaaaaaat gaaggtcatg atgttatgga
      241 ttttaaaacg ggtgatgaac ttttagaaca atttaatata aaggagtgtg acttagtaat
      301 actagatata atgatgcctg gctcaagtgg ttttgaagta tgtacaaaac ttcgtgagaa
      361 aagtacagtc ccaataatca tgcttactgc aagagataca gatatagatt atattacagg
      421 gataacctta ggtagtgatg attattttac aaaaccattt agcccaatgt ctttggttat
      481 gagagtaaaa tctatattta gaaggataga gtttgaaaag aaacaaaatt atgataaata
      541 tagtaactcg atagatatgg aattaaaatt tggtgatgta ataataaata aaaagaataa
      601 aatcgttaca agtaaaaatg taaatataga ccttacacca aatgaatata acctattgac
      661 ttatttgttt gaaaatatag atagagcagt ttccagagat gaattattaa acaaaatatg
      721 gggatacgat atagaagttg agacaagggc tgctgatgat acagtgaaga gattacgtaa
      781 aaaaatttta aatacaaata ttttaataga aactgtatgg gggtttggat ttaggttgaa
      841 ggagaaaagt taagatgaag aatggaaatg acaagaatag aattggaaag attaaatcca
      901 aatttaaatt aaagttctca aagaaaaata taagcataaa aactaggatt ttgttgagta
      961 tactttgttt gataattata gtatttatga taatattagt atcttttaat gtatttcttg
     1021 atacatatat aaaaacaact gcgaatgaag aattgacaaa gtctacagaa atagtagaac
     1081 atatggatag taattttaga cctattaagc caccacaaga tgatggaaag cttcctccca
     1141 aagtattatc taattttatg agaaatgtac aagataaagt taggatggca gaaacacaat
     1201 cagatgctga tgctatggta gttgattcta agtataacct gatatttcca acaagagagg
     1261 atgatttctt aaaaaatgtt gatgagatgg agctgattag ggagtgtatt caaaatgaaa
     1321 aattagattt aaattcagat gaaaatacac ggatatctac cagaaataag gattattata
     1381 tttcaactgt aaaaattact agtatatatg gtgaacaaga caagtatctt atacttttta
     1441 tagacatatc aaaaactcta aatctagcac aaaagataaa tattgtatta atatctgtaa
     1501 tgtgttttgc tggaatatta gcaatattta cagctgtgat tttatctgag aaaattgcta
     1561 aaccgataaa agagttgtgt gagtttgcaa aaaaaatggg tcaaggagat ttcaaaagaa
     1621 cctactttga cttttcagat aaagaattag tagagctctc aactgttatg aataagagtg
     1681 ctgagtatct ggataagtat gataatgaac aaaaaatatt ttttcaaaat gcatctcatg
     1741 aattaaggac accacttatg tctattaaag gttatgcaga agctataaaa tataatgtta
     1801 tagatagtaa acatgcaagt gatataattc ttgaagaaag tgataggtta agtgatatgg
     1861 ttgaagattt attatacatt tctaaaatag ataatataac taaagatttt gaacttgtag
     1921 aatgtgattt aagagaagta ctttcaaatt gtggagctag gcaaaatgta agagctataa
     1981 ataaggggat aaaatttatt tatgaatttg atgaagaaat ggttttattt gaatgtgatg
     2041 aaaaaaacat ttccaaagca tttatgaatc ttatagaaaa tgctttgaga tacgctaaga
     2101 gtgaaataaa aatagtgtgt aagtataatc aaaaaaatat agttgtgata atagaagatg
     2161 atggaattgg aatcaagaaa gaagatttac ctcatgtttt tgaaagattc tataagggag
     2221 tagggggaaa tcatggaatt ggattatcaa tagttaaatc tattgtaaat aagcatggtg
     2281 ggcgtatata cgtagaaaat ggcaaaaaag gagctaaatt tactatatta tttaaattgt
     2341 aaaaaaatta gagaaaatat agagatgttt gaagttgttt tttatatata tctgttgtat
     2401 actgttgaaa aaagaacaat attaagctga catatattac gatagttgac atttaaagta
     2461 aatgcttaaa tatagatacg aaaggaaaag taaaatctga agtgtattta ggtttaagta
     2521 agcttcttat tttataaaaa atatgtatga aagaacagct gatttttaat attacaaatt
     2581 tagtaacggt tgtatttgaa gcttttgtca tccatatgtt tttatcagac tttttaggtc
     2641 agaaagaagg gtatataaaa gttgtaagat atgctaaact gggttttata atatgtttag
     2701 gattctgtaa tttaataact ttaaacccta aaatcacaat gcctttaatt ttcatcctta
     2761 ttttttcaac atcattttta tataaaggaa atttaaagac acgattgttt actactgttt
     2821 tattaagtat attctttata ctgtcagaaa ttgtagttac aagtattttt gttttatttg
     2881 taaaagaagg ctttgaaata atgcttgaaa ataatagtat aagagtattg gcgacaattt
     2941 tatctaaaat tgtctttttg ttgacttgta aaattatttg tctatttaaa aaggatgtac
     3001 atttagatat gcccataaag tattggctcc ctttattttt aatacctata tttagtttat
     3061 ttctgtctgt ttctatcttt gatgtaagta aattttttag tcttgaaagt ttaaaatttc
     3121 taagcttaat atctagtgtt ggtattttat atattaattt tattgtcttt tatttattta
     3181 aatttattat agataaaact aaactatcta tgaaatatga actacttgaa aaagaaataa
     3241 ttcataagga agaattaaga cttagtaatg agtgttataa aattattgtt gaacagactg
     3301 attctgtcgt tttcgaatgg aatatcaaag aaaataaatc atttgtatcg caggcttgga
     3361 ctgaaaaatt tggatataac aatgcatgta agaatatttt taaagaaatt aaagataaag
     3421 acttagttca ttctgaagat aaagctatat ttgaaggttt tcttgaaagt attaaaaaaa
     3481 agaatatgca caatcaagca gtatatcgtt taaaaaaatc taatggtgaa tatatttggt
     3541 gtagaacatc aattacaagc atttataatg atgaaaatga acttttaaga gttgtcggag
     3601 taattgtaga tgtagatagt gatataaaaa aatatgaaga gttaagaact agagcagaaa
     3661 gtgactcatt gaccaatata tacaataaag gtacatttga aaaattagtg gaagaaacta
     3721 tagttatgaa tacaggtgat aaaaaagatg cattattcat tattgatttg gatgatttta
     3781 aagaaataaa tgataatttt ggtcatccat ttggtgattt tgtactaaaa acatttgctg
     3841 ataagataca aactagtttt ggtagtaaag acttagtcgg aagaattggt ggagatgaat
     3901 ttgttgtata tatgcaagat tatgttacag aagtaaattt gcataaaaaa gctaaagaat
     3961 taaatagagt actttcggat aattacactg atttgagttt tagttttgat gcttctgtca
     4021 gtataggtat tgcaaggtat cctcaagatg gaacttcatt ttttgaattg tttaaaaatg
     4081 cagatagagc actttatagc ataaaagcat caggtaaaaa ttcatattgt ttatttgaag
     4141 aagaactata tgtacagtga atttgaattt agattttatg tgagagtaag atttatatat
     4201 acttgtggct gtctgattta taaaatatgt tactttgtat atttttatat gtttcagtaa
     4261 ggttaattaa catgagcaaa ggtgtaagta aatttatatt agtttaagtt tacttacacc
     4321 tttataaaaa tacaaataat agattcattt acattcttaa atgattaaag ctctttacct
     4381 tctaaacatg cataacatat cgttataatt ccagtaaata agactaaaat gcccattact
     4441 aagattacaa tttcatcatc tattactcca aatgttttta aagtaactta tttcgctttg
     4501 tatcataata atttgtctct ttttacattt taacttctgc tgagatttga gttagatatt
     4561 cattagaatc tcgcacactt atatcatata gaagatattc ttcataaaca aaatccccaa
     4621 tacgtaaatt attctgatta aaaaaattta ataacttttc ataagccttg taaatagttt
     4681 cataactccc tttatgataa gcagttacat aaagtccctt tggtttgatt gatacaggat
     4741 atttcttgta ctctttatta acttttgtaa ataaatatga atatgattca aagtctttat
     4801 taattatatc ttcaccttta atgattgagc caatcgtacc ataatcactc aattcatagt
     4861 tgtccataaa gttaatacat tcatataaaa aattttcttc ctcatctcct aaaaactgtt
     4921 ctttatatgt aacaggtgtt ttgaccaagt actcttcttc atgttctttt aaagtaatag
     4981 tattcgcatc tatattacat gcacttttag taaatgaaat agtagattcc attagagctt
     5041 gaatattatt tagtttttca atttcatttt taatatcaat ggttttcttt tctaaaagct
     5101 caattagtaa attaggtgtt cttttgtcta tataagcttt aatttctttt aaaggcattt
     5161 ttacttccct aagtgaagaa attataccaa aaatgctaag ttgatggtat gagtagtatc
     5221 tatatccatt ttctttcttt aattctggtg agaaaagacc tatatcatca taatggaaaa
     5281 gtgttttttt attgattcca caaatctttg caaattctcc agttgtaaaa taattttttg
     5341 aaacttgact cataattata attcctcctt gactatcctg ttacagtata gtttatcata
     5401 gtattttgta aaggagtgtg attatatgaa aaaattaatt cattttttaa aaccatatag
     5461 agttttaatt gttgtagttt tgatatttac gtttttacaa acacttggaa ctttgtatat
     5521 accaacactt acagcaaata tagtaaataa tggtgtagta aagggagata tagattatat
     5581 tgtaaaaaca ggtttaatga tgatgatagt agctggtata acagctttat cagctgtgtt
     5641 agtttgtaaa gtatcagcaa atctttcatc tggattttgt agagatatta gagaagcagt
     5701 atttataaaa tcacaagatt tatcaataaa tgattttaat aatataggta cagcatcaat
     5761 gattactagg agtactagtg atattacttt aataggtcag tctgtgttta tgtttattca
     5821 attagtatta ccagcaccaa ttataactgt ttctggtcta ttcttagcat attctataga
     5881 taaagcaatg acaattatta ttgttgtagt aatgttttta ttcatgcttt cagcattttt
     5941 agttggtaaa aagcttataa agttgtttaa aatgatgcaa ataaagatgg ataatatgaa
     6001 tagggtgtta cgtgaggtag taactggagt aagagttata agagctttta ataggagtcg
     6061 ttttgaaaaa aagagatttg atagaactgc aatagattat tctgaaacag caatttcaat
     6121 aaataaaata tttgcagtac ttatgcctat tgtaatgtta ataatgaatt taggtatagt
     6181 aagtattatt tggtttggtg ggatgagagt cagtaatgga aatatggaaa taggtcatat
     6241 aatggcactt gttgaatatt gtatcttaat tttattctat ttaatcatgg gagtaatggt
     6301 atttatgtac atacctagag caggtgcatg tgcagataga gtaaatcaga tattagatat
     6361 agaacctgaa attgtagatg gaaatggtca taaagatact gtctcagaga gaggacattt
     6421 agtatttaaa aatgtaacct tttcatatgc acaatcagaa gaacctgtgt taaataatat
     6481 aacatttgaa gcaaaatctg gagaagtaac tgcaattata ggaagcactg gctcaggcaa
     6541 atctactatt gcaaatataa taccacgttt ttttgaaatt caatctggag aaatatctat
     6601 aaatggtcag gatattaaga agattcctca aaaagaactt agagataaga ttggatttgt
     6661 accacaaaaa gcttttttat ttagtggaac aatagaagaa aatataaggt atggaaaaga
     6721 agatgcaagt attgaagaag taaagcatgc tgcaagtata gctcaagctg atgaatttat
     6781 ttatgatatg gaagacaagt atgactcatt tgtagcacaa ggtggaaata atttgtcagg
     6841 tggtcaaaaa cagagaatat ccattgcaag agcgttagtt agaaagcctg aagtatatgt
     6901 ctttgatgat agtttttctg cattagattt taaaacagat aaaagactta gaaaagcgtt
     6961 gaaaaatgaa atcaaagatt catcagctat aattatagca caacgtataa gtacaatcat
     7021 ggatgctaat cagattatag ttttaaatga tggaaaaatt gtaggtattg gaaaacataa
     7081 agatttactt gaaaattgtg aagtttataa gcaaattgcg gattcacaac ttagtaaaga
     7141 agaacttgca taaaatgaag aattaatctg atatttggag gtgtatgata tgagtgaaaa
     7201 aagaatagat gaacaagata tagaagtact tagttttgaa gatggcatgt cagcagaaaa
     7261 agctaaggat gcaaaaaaaa ctactaagag attattaaaa tatatggcaa aacaaaagtt
     7321 taaaatatta attattttta tttcagtatt gataagttca gcgcttacag ttttagcacc
     7381 tatggttatg ggaaaagcta ttgaccaact atttaatgga ataaaaactg cagtccaaac
     7441 aggtacaaaa ttcagtgtga attttagtac tatgggaggg atagtatcaa tacttctagg
     7501 gttgtactta attagtgcag tatttatata tattcaacag tatattatgt caggagttgc
     7561 acaaaatcta gttcttagca tgagaaaaga tttaagtgat aaactcaata aacttcctct
     7621 taagtactat gattctcata aaaaggggga aacacttagt atagtaacaa atgatttaga
     7681 aaaagtagca gatagtttac aagaaggatt aatgcaactt attacagcag tagttacagt
     7741 agttggttct attgtaatga tgataagtat aagtgtacca cttacaatag tatcagctat
     7801 aacattactt gtttcattgg gtattactgt tgtaattgca agaaaatcac aagaaagatt
     7861 ctctgaaaat caaaaggcac taggagagtt aaatagcaat atagaagaga tatttactgg
     7921 tcaaatagtg gttaaagcat ttagtaaaga aaaggatact ataagaaact ttaaaatatt
     7981 aaatcaaaat ctttataatg caagtagaaa agcacagttt tcgtcatatg caatatctcc
     8041 aattattaga tttataaacc taattggcta tgttattata gcagttgtag gtgggatatt
     8101 tgcatcaact ggagcaatga ctcttggtag tatacaagcg tttattcaat atgtaaatca
     8161 agcatcagag cctactacag aaatatctta tattgtaaat atgcttcaag cagcaatagc
     8221 atctgcagag agagttttta cagttatgga cgaggtggaa gagataaagg atgaagaatc
     8281 ttcaaaggtt attagcatgc ctaaaggtaa agtacaattt gagcatgtta aatttggata
     8341 tagtgatgat tttattctta tgaaagatat taatatcaat ctaaatgcag gagataagat
     8401 tgcaattgtt ggacctacag gagctggaaa gacaactctt gtaaatttac ttatgagatt
     8461 ttatgagata caaggtggaa gaattactat tgatggtgtt aatataaaag atttaaagcg
     8521 tggagaactt agaactatgt ttggtatggt tcttcaagat acatggctgt ttaatggaag
     8581 tataaaagaa aatattgcat atagtaagtc agatgccaca atggatgaaa ttgtaagagc
     8641 agcaaaatca gcaagagtag accattttat aaggacttta ccacaagggt atgacactat
     8701 attgactgag gatgcttcta atctatctca aggtcaaaag caacttctaa caattgccag
     8761 ggcaatactt tcagacccat cagtattgat tcttgatgaa gcaacatcta gtgtagatac
     8821 tagaacagag gtagaaattc aaaaggcaat gaataacttg atgaagggaa gaactagttt
     8881 tgttattgca catagattat caactattcg agatgctgat ttaatattag taatgaaaga
     8941 aggaactatt attgaacaag gaagccataa ggaacttatt gaaaagaaag gattctatga
     9001 agaactttat aacagtcaat ttacaagtga atatgatgaa gatgttgtat gattatcaag
     9061 ttttaggcaa ctaaatgatt gataaatatt aagttaaata tagtaacatg taaggttata
     9121 tggaataaga gtatttctct atttcatata acctttttta tttatcaaaa taagataaaa
     9181 tttcctttct aaattagatt gaagaatgta tttatcaata taaaagtaaa ataatcatta
     9241 ttattagtga agtaaatatt gtttgccaca tatatgccat aaagatgcac ttattttacg
     9301 gagatttaac aaagtagtgt aaagtatact ctaaatataa aataaatcaa atagagttaa
     9361 ataaattgag aggtgatata aatagtgaat aaaaaattga actatagatt tgaaatgaag
     9421 cacaaaataa ctgaagcaga tgtgttagct ttaaaatcaa gactctatcc aataatgaag
     9481 aaagatgaaa atgcatctaa agatggaaaa tatcttatta ggagtttata ttttgatact
     9541 cctgaagata aagcactttt ggataaatta aatggcgttg caataagaga aaagtttagg
     9601 ataagatttt ataataatga ctgctcttat ataaggttag agaaaaaaat caaacattac
     9661 aacatgacat caaagctatc aactaattta accaaaaaag aagtaataaa tatactaaat
     9721 aatgatattg aatttctaaa agagtcgaca aattgtttat taagagaatt ttatttgaaa
     9781 ttaaaatgtg aaagattaga ggcaaaaagc atagttgatt acaatagaga agcttttatt
     9841 tatccagttg gaaatgtaag agttacaatc gatagtgata ttaaaacttc tgtaaattcg
     9901 gtagatttat ttaataaaga tttgccaact atttcggtaa ttgatgagaa tatgactgta
     9961 ttggaggtta aatatgatga atttatacca gattttataa aggatttaat tcaaattaat
    10021 aagactacct ctacagcagt ttcaaagtat gcttcaagta gattatatat ttaagaataa
    10081 aggctatgat ttatataaag atatacataa ataaggttaa aaaacaaata agttaaaaat
    10141 aaataaaata aaaaataaat aagttaaaaa taggaaggat gattttaatt atgacattta
    10201 atgatatttt taaatcaagt tttatagaaa acgtatcagg tttttcattt gtggacagtg
    10261 ctttagcact aggttcagct tttttagtag gtttgtttat atatatggtc tataaaaaga
    10321 cttatatggg aattatgtat tctcgaccat tcaatgtgtc gcttgtagca cttacaatgc
    10381 ttacaacttt tgtaatattg gcggttactt caaatgtagt tttatcctta ggtatggttg
    10441 gtgctttatc tatagtaaga tttagaacag caattaaaga cccaatggat ttagtatttc
    10501 tattttggtc attaggttca ggtatagttt taggagcagg tttgattccc ttagctgtca
    10561 tgggttcaat aattatggga ttgattctaa tattcttttc aaataaaaca atatctgaaa
    10621 ctccatatat attgatggta aattgtaata atgaagattc agaagatata gcaactgata
    10681 aaattaaaaa agtatttact aaatatcaaa taaaatcaaa aagtgttaca ccagaaaaag
    10741 gaatagaatt agtgtttgaa gtaagaatga aagatggaga aacaagtctt ataaatgact
    10801 tgagtcaagt agatggagtt actaatgcag ttcttgtaag ttataatggt gactatgtag
    10861 catagagagg agtaatcttt tatgaaagat aaaaaattta cccttcttat ctcgattatg
    10921 attatatttt tatgtgctgt agttggagtt tatagtacat ctagcaacaa aagtgctgat
    10981 ttatatagtg atgtatatat tgaaaaatat tttaacagag acaaggttat ggaagttaat
    11041 atagagatag atgaaagtga cttgaaggat atgaatgaaa atgctataaa agaagaattt
    11101 aaggttgcaa aagtaactgt agatggagat acatatggaa acgtaggtat aagaactaaa
    11161 ggaaattcaa gtcttatatc tgtagcaaat agtgatagtg atagatacag ctataagatt
    11221 aattttgata agtataatac tagtcaaagt atggaagggc ttactcaatt aaatcttaat
    11281 aactgttact ctgacccatc ttatatgaga gagtttttaa catatagtat ttgcgaggaa
    11341 atgggattag cgactccaga atttgcatat gctaaagtct ctataaatgg cgaatatcat
    11401 ggtttgtatt tggcagtaga aggattaaaa gagtcttatc ttgaaaataa ttttggtaat
    11461 gtaactggag acttatataa gtcagatgaa ggaagctcgt tgcaatataa aggagatgac
    11521 ccagaaagtt actcaaactt aatcgttgaa agtgataaaa agacagctga ttggtctaaa
    11581 atcacaaaac tattaaaatc tttggataca ggtgaagata ttgaaaaata tcttgatgta
    11641 gattctgtcc ttaaaaatat agcaataaat acagctttat taaaccttga tagctatcaa
    11701 gggagttttg cccataacta ttatttatat gagcaagatg gagtattttc tatgttacca
    11761 tgggatttta atatgtcatt tggtggattt agtggttttg gtggaggtag tcaatctata
    11821 gcaattgatg aacctacgac aggtaattta gaagacagac ctctcatatc ctcgttatta
    11881 aaaaatgaga catacaaaac aaaataccat aaatatctgg aagagatagt aacaaaatac
    11941 ctagattcag actatttaga gaatatgaca acaaaattgc atgacatgat agcatcatat
    12001 gtaaaagaag acccaacagc attttatact tatgaagaat ttgaaaaaaa tataacatct
    12061 tcaattgaag attctagtga taataaggga tttggtaata aagggtttga caacaataac
    12121 tctaataaca gtgattctaa taataattct aatagtgaaa ataagcgctc tggaaatcaa
    12181 agtgatgaaa aagaagttaa tgctgaatta acatcaagcg tagtcaaagc taatacagat
    12241 aatgaaacta aaaataaaac tacaaatgat agtgaaagta agaataatac agataaagat
    12301 aaaagtggaa atgataataa tcaaaagcta gaaggtccta tgggtaaagg aggtaagtca
    12361 ataccagggg ttttggaagt tgcagaagat atgagtaaaa ctataaaatc tcaattaagt
    12421 ggagaaactt cttcgacaaa gcaaaactct ggtgatgaaa gttcaagtgg aattaaaggt
    12481 agtgaaaagt ttgatgagga tatgagtggt atgccagaac cacctgaggg aatggatggt
    12541 aaaatgccac caggaatggg taatatggat aagggagata tgaatggtaa aaatggcaat
    12601 atgaatatgg atagaaatca agataatcca agagaagctg gaggttttgg caatagagga
    12661 ggaggctctg tgagtaaaac aacaacatac ttcaaattaa ttttaggtgg agcttcaatg
    12721 ataataatgt cgattatgtt agttggtgta tcaagggtaa agagaagaag atttataaag
    12781 tcaaaataag attaaaattg aatataaata attttaatac tgttaagtct aaatatttac
    12841 ttagcagtat ttttttagaa aataatgtat ttggttaata atataaggta ataaattgat
    12901 aaaaattaaa tacagcatat taataataca taataaagta ataaaaaaac tgtttaagta
    12961 taataactta tatttagaca gtttttttca tttataaata atataaatga aattgaaaac
    13021 atttgaagga tagaaattgg ttggataaat gtataaatta cttcaccaaa aaataatgac
    13081 aaaaattgta actaagttgt aataaaatgg tagttattta gcataaaata atgtatcata
    13141 gaagtatatt ataaaattaa taaaataaga tttttgtaag aaaactgctg gcttttgata
    13201 tttagagtga gtagttaaat tatgtttagg aggggtagaa tttgttgcaa aaagtattat
    13261 ggaaattttt aaagctagta gtcggtttat ttatatgttc agttggtata gtattgacga
    13321 taaattgtaa ccttggatta tctccctggg atgtatttca tcaaggactt tcaaatcata
    13381 taggaataac tataggaact gcttctataa ttgtaggctc tatagtagtt attgctgatg
    13441 tcgttcttgg agaaaatgta ggatggggaa ctgtttttaa catgctacta attggattct
    13501 ttatggattt acttttatat agtaatttaa ttccagaggc tgatagttta tttgtaggaa
    13561 taattatgtt gatattagga ttggttcttt tgtctgttgg aatggtattt tatatgggaa
    13621 gtggtttagg aagtggacct agagatggtt tgatggttgc aattcaaaag aaaacaggaa
    13681 aatcacttaa attaataaga ggtactatag aagttggagc attaatagta ggatttttat
    13741 taggtggaaa agttggtata ggaactataa taagtgcatt tggattgggg tatttcacac
    13801 aaatggtatt tggcttattt aaattagatt gtagtaagat taaacataga tttatagtag
    13861 atgatataaa atttatcaaa gtgtatatga gtggtgagaa aaaagctgct gttcaaaata
    13921 tagttaagta atttaagaat aaattcaacg aaatgttaag tattttaaat taacattttg
    13981 tttagataga taaattgaat attaaaagaa tattaaaata tgaggattgc tagaacacta
    14041 taaaatatag atttctagca attttttatt tgttcaatat ttttttagta ctagaagtct
    14101 tattctctat ttaatgaatg aattaattta taattagaga tactaaactt tatagatatt
    14161 aatataaaca cctttaaact gtgtattttc caaagccttt aaaatgcttg tatttattct
    14221 aaataaaaaa ataaaaaaat gtcaaaaaaa ctcttgtatt atatccaaat tttatatata
    14281 attacctatg ttgtttagaa attttaaact caatgtttag taaacaaaat gtttagtaaa
    14341 ataaaacaga aactaggagg tgcaacatgg atataggtga aaagataaaa agattaagaa
    14401 cagaaaaaca actgacccag gaagagttag ctaatagatg tgaattgtca aagggattta
    14461 tttctcaatt agaaaataac ttaacatcac catccatagc tacccttata gatatacttg
    14521 aaatactagg tacaaattta agggaatttt ttaatgaaat agatgatgaa agaatcagtt
    14581 ttacaaaaga agatatgttt gaaacagaag atgaagattt aaaatataaa ttaaagtggt
    14641 taattccaaa ttcacaaaaa aatgaaatgg agccaataat aataacattg tatccaggag
    14701 gacagtataa agaagaaaag ccacatgaag gtgaagaatt tggatatgta ttagcaggtt
    14761 caatatatgt ccatataggc gaaaagaaaa ataaagtaaa aaaaggagag agtttttact
    14821 ttagaccgaa agcaaatcac tatatatcaa acgagggcaa aactacagca aaagtgattt
    14881 gggtaagtac gccaccatca ttttagaata gaggtgttta ataattggta gaaaatataa
    14941 tagaattaag ggatatatct aaacattatg aagaacttac tgttttagat aatttcaatt
    15001 tagatataaa gaaaaatgag tttctaacat tacttggacc aagtggatgt ggaaaaacta
    15061 caacattaaa aataatagca ggatttgagt atgctgatga tggtaaagtt ttatttgaag
    15121 gtaaggagat aaataatttg ccaccatatg aaagacaagt aaacacagta tttcaaaaat
    15181 atgctttatt tccacacatg gatgtttatg aaaatgtagc ttttggatta aaaattaaaa
    15241 agactccaaa agatgtaata gatgctaaag taaaagaggt tttgaaactt gttgcactag
    15301 aaggttttga aagacgacaa gttgaatcat tgagtggagg acaacaacaa agaattgcaa
    15361 tagcaagagc tctagttaat gaaccaaagg tattattact agatgaacca cttggagcac
    15421 ttgatttaaa gttaagacaa gagatgcaaa tagaattaaa gagaatccaa aaaaaattag
    15481 gaataacatt tgtttttgta actcatgacc aagaagaggc tcttactatg tcagatacta
    15541 ttgttgtaat gtataagggc aaaattcaac aaatgggaac accacaagat atatacaatg
    15601 aacctaaaaa ttcatttgta gctaagttta taggtgaaag taacatattt gatggaatta
    15661 tgatagaaga ttataaagtt aatttctgta atagagattt tgagtgtgtt gataaaggat
    15721 tcgaaaaaaa cgaaaatata gaagtagtaa taagaccaga agatataaaa atggtaaagc
    15781 cagaagaagg aatgttaaag gggaaagtta catctacagt gtttaaagga gtgcattacg
    15841 agatagaatt gaatgaaaat ggaagattgt ggatacttca taatactaaa aatgctgagg
    15901 ttgggactga actaggcatg gatatatatc cagaagatat ccatataatg agaaaagaga
    15961 ataactaaga tgaaaagaaa atctttttta gcatatccat atgtagtttg gagtgcgata
    16021 tttgtaataa ttcctttaat attagtagta ttttttagtt ttacaaaaga atcaggtgga
    16081 ggttatgcct ttacacttga gaattataaa gaagtaattg accctatata tatgaaagtt
    16141 tttgggcgtt ctattctttt agcaggagga gctacattaa tatgccttat agttggttat
    16201 ccagtggcat atataatttc aaaggctcgt gtaagtagaa gaggttcatt aatattattg
    16261 tttattcttc ctatgtggat gaactttctt ttaagaacat atgcatgggt tgctatatta
    16321 ggaaaaaatg gacttttaaa tacattttta ggttggtttg gaatacaacc attagcaatt
    16381 ttgtatacta attttgccat acttttaggt atggtgtata actttttacc atttatggtt
    16441 cttccaatat atacagcact atcaaagatg gataatgatt tgataaacgc tgctcatgac
    16501 ttgggtgcaa ataatatgac agtttttaga aaaattatat ttcctttgag tttgccaggt
    16561 gtaatgtctg gaataactat ggtatttatg ccagcagtca ctacttttgc aatatcaaga
    16621 ctgttaggtg gaggtaaaat aatgctggtt ggagatttga ttgaacaaca gtttacagtt
    16681 gttggagatt ggaactttgg ttcagctata tcgatattta tgatgatagt aatattaata
    16741 tctatgtcta taatgtcaaa atttggagat gaatctgaca aagaaggcgg tgggttacta
    16801 ttttaaaatt aaagaaaata acttctaata tatatttagc attagtattc ttatttttgt
    16861 atgcacccat atttgctttg gtactatttt ctttcaatga ttcaaaatca atggcaagat
    16921 ggaatggatt tacatggaag tggtatggtc aattacttca aaatgagagt ataatgagtg
    16981 ctttatatta tactattgta atagctatat tagcgtctgt aatatctaca atagtaggaa
    17041 ctataagtgc tataggaata cataagatga gaggtaagag taagaaatta atactaaatg
    17101 taaactatct tcctatttta aatacagaga tagttacagc agtagctctt atgagtctgt
    17161 ttgtatttgt aaaaatggaa tttggattta caacaatgct attggcacat ataatgtttt
    17221 gtttgccata cgttatactt tcagttttgc caaaaatgaa gcaattacct gataatatag
    17281 aagatgcagc tatggacttg ggagcaacac ctatatacgc tcttagaaaa gtaattttac
    17341 cacaaataaa accaggtata gtttctggat ttttaattgc atttactatg tcaatagatg
    17401 actttataat aagtttcttt aatgctggaa atggtgtaag caatctttct atagaaatct
    17461 atggaatggc tagaagaggt ataaaacctg aaataaatgc attatcaaca ataatgtttg
    17521 cagtggttct aggtttactt ttactagcta ataaaaaaga atctatagta agggggatta
    17581 aataatgatt aagtttaaaa aagcaatatc ccttatagct gtaggtatga tgacagttac
    17641 tttatttaca ggatgtaata aagcaactga ttctacaaaa gttttaaatg tatataatgt
    17701 tggagattat atagatgagt ctcttataga taagtttgaa aaagaaacag gaatagatgt
    17761 tcaatattca acttatgata ctaatgaaat gatgtatcaa aaagtaaaga gtggtagtac
    17821 acactatgat ttagtatttc cttcagacta tatggtagag aaaatgaaaa atgaaggtct
    17881 tttggaaaaa ttagatttta agaatatacc taatatgaaa tatttagata agagtttttt
    17941 aaatcctgta tacgacaaaa ctaatgaata tagtgttgca tatatgtggg gaactcttgg
    18001 aatactgtac aataagaaag aagttaaaga ccctatggat agctggaata tactttggaa
    18061 tccaaagtat aagggaaata taatgatgtt tgactctgtt agagatacta tagggataac
    18121 tcttaaaaaa ttaggatata gcatgaatag tgtaaatcca aaagaaataa atgaagctaa
    18181 aaatctttta atgaaacaaa aggatttagt attggcttat gtaaatgatg aaggtaagga
    18241 tagattgctt ggtggagaag tggcaatggg tatgctgtat tctggagatg cagttacact
    18301 aatggagcaa aatcctgacc ttgattatgc tatacctaaa gagggaacta ataaatgggt
    18361 agatgctatg tgtgtaccta caacagcaca aaataagaaa gaagctgagc tgtttataaa
    18421 ctttttatta gacccagaga atgcaaaagt aaatgctgag tacattgggt attcaacacc
    18481 taatacagga gcactaaaat tattagaccc agaaataact cagaatcctg ttgcatatcc
    18541 atctaaagaa gtgcttgata aatgtgaaac ttttgaagat attggtgaaa atataaaatt
    18601 atatgacaag gcttggatag agttaaaatc aaaatagggt cttgttggtt taagtaaatt
    18661 tacttaataa atacttaata aaactgttct tttttagaaa atttattttc taattattga
    18721 acagttttat tttttgttta agttatattc atatgcaatt taaatagttt attaataaat
    18781 gaaaacttat ttgtataatg actttaataa taattagaaa aaatgggcaa cttaatagaa
    18841 taattggagg tgtaaattta taaaaaatga ataggataaa taaaaaaata gatttattaa
    18901 tattggcttt gctcgttttt atatttttaa ttgttggaat agtaatacta tcgattagga
    18961 cagaaaataa attgaatgtg ttcataatgt tagcaataat tttttttata ataatgttaa
    19021 cttatttatc aaattcagta gtggggttga taacaagttc aataattata tttatgtata
    19081 catcctatat tttatataac aatattactc acaatatgga tgttgaattt atatcatata
    19141 tgtggataat agcaacacca gtatcttcaa ttataatggg taatctgaac aaaagcataa
    19201 atgaattgca aaatacaaat aaaaaactat ctgaacagta taaggaatta gtgactattg
    19261 atagtgaaac tggacttaga aatttaaaga ttttttataa tgatgtaaat atggagataa
    19321 gtaaatctat tagacataat actgattttt ctcttatgat agtaaaatta ccatactacg
    19381 gaaacctaca gactatattt ggtgaaaaca aaactaataa aatagtaaaa tatattggtt
    19441 caaatattat agaatgtaca agaaatgaag atataattta tagtttacaa aaagatatga
    19501 tagggatact aatgccaaat acatctttgg aaggttcaaa agttgttaaa gacagaataa
    19561 agaaaaggat aaaagaatta aatttagatt taaacaatag gggaaaatat gtaaatatag
    19621 atgtcaaaat tgcattttta caatataaga gtagttttgg agatagtata aattttaaga
    19681 atatagttga agaggaactt caatatgatg tttaaaatat ttaataaaag tctattaaaa
    19741 ttagtagttg tattatcaat agtactgaca atatcaaatt ttagcttatc ttcatatgca
    19801 tcagaaatta cttccagcac agataaggta ttaatcatat atgattctaa gaaagaaaca
    19861 gcttataata gagatatttt aaatattatg aggactctat tgggaagatt tagttcagat
    19921 atagagctat taaaattgag taactatgat ggtgagataa ataaaaatta ttacagtcat
    19981 atatttattt taggaatcaa tgaaaactca tataataatg ataaaaacac taaaaacttg
    20041 attagttcct taaatttata taaaggaact atatgttggt taggatatgg tatagaaaat
    20101 cttttggaac ataaaaaata caatttagac tatgtaggaa aaacaaacaa tatagttagt
    20161 gtaaattata gaggtaaatc atataacttg gatgaacatt atgtttttaa cattgtagaa
    20221 tcaaaagata caagtaataa agtaatagga agtattaatg ataccttaaa taagtatcca
    20281 tatataataa atgataaaaa tcttttttat gtatcaaaat tagatttaga tggagtttta
    20341 ttttatatat tttgcgattc acttaatgat atttttaata ttaagacgtt tgataaagga
    20401 cgtatatttg taagaataga agatgtacat gcttttagag aaccaaaaaa tcttgtagag
    20461 atagcggatt atttaagtag taagaatata ccatttacga ttgcattaat accagcatat
    20521 gtaaatccta aaaatcataa ggtaataact ttatcagaaa gccctgaaat tgtcaaagca
    20581 ataaaatata tgcaagataa aggtggaact gtgatattgc atggatatac tcatcaatac
    20641 aagaaagaag aagtttctgg agaagggtat gaattttggg atggtaaaaa agatgaaccc
    20701 ttaaaagaaa atatgaagat atttgtcaaa gatagagttt tgaatggtct tagagtatgt
    20761 atagagaatg gaatttatcc tcttgcattt gaagcgccac attatgcaat ggaatcagag
    20821 ggatataaag aattaaaaaa atatttttct acttatatag ggcaacatca aaataatgat
    20881 aaaaaattta gcacaaatac atatccttat attattaggg atacagagga gtttaatata
    20941 tttatacccg aaaatttagg atatatagac ccagaagata agtttacttt tcaaaatata
    21001 aaagaaaatt tagataaatt atccattgta agaggtttta gtggagggtt cttctttcat
    21061 tcatatttaa acatagagta tctaaaaaac acaatagaat atttagaaaa acagaatata
    21121 gaatttatga atttaagaga ttttaataat tgggtaaaag ttgatgaaat acaaataaga
    21181 aataatggag atgaaattat agtcaactat gataaggact tagatgaact aactaaaagt
    21241 gatactagat ttaaatccat atccaatatt agtaaagttt taatattcat agtatctata
    21301 agtgttttaa tatttgtgat tatatttata tattttaaga gaatagataa aaagaaattt
    21361 ttaaaataaa ggattttata ttagaatcaa tattttaaaa tattttagga gaaatttatg
    21421 agagatttaa atgtatcaga gtatttgttc gtatttagtt tgtttagtat atggtcttta
    21481 ttgcttataa atattatttt agctatgggt ggatatatat tttattttaa aaactttgat
    21541 aaagaaataa aagaaattga tgaatatcct atgatatcaa tacttgttcc tgctcataat
    21601 gaagctaaag tgataggtag aactgtggag tctttgctat tactcaatta tcctaagagt
    21661 aagatggaac ttattgttat aaatgacaat tcttctgata atagtaaaga aattttagaa
    21721 aatataaagg ataggtacaa caattataat ttcactataa taaatacaga tagtttaaca
    21781 ggtggaaaag gaaagtctaa tgcattaaat attggatata cgatttcaaa aggagatttt
    21841 atagctgttt atgatgcaga taacacacca gataaaaatg cacttagata tctagtacaa
    21901 actatagtaa tgaatgatga attaggtgct gttattggga aatttaggac tcgaaataaa
    21961 aataaaaacc tattaaccaa atttataaat atagaaacat taagctttca atggatgtca
    22021 caagctggta gatggcaact ttttaatcta tgtacaatac caggaactaa ctttatattg
    22081 aggagaagta tcatagaaga aattggagga tgggatagta aagcaattgc agaagataca
    22141 gaaataagtt ttaggatata taaattggga tacaagataa agcttgtacc acaatctata
    22201 acatgggaac aagagccaga aactgttaag gtgtggataa agcaacgtac tagatgggca
    22261 aaagggaata tatatgtatt aatgaaatat ataaaaaata tatttaaaca gggaagaaat
    22321 aagattgtgt ttgatatagc ttactttttt tctgtatatt ttctattttt aacatctgta
    22381 attatatccg atattttatt tgttttaagt atatctaaac tagtagaaat ttctattcca
    22441 attaactttt ttctaatatg gatactatct tatcttttat ttattataga agtgagtata
    22501 agccttacta tagaaaaagg tgaagcaaca attgaaaata tattcatagt ggcaataatg
    22561 tattttacat actctcaact atggctgttt gtagctataa aaggaatgat agagtatcta
    22621 aaagatataa tttttaaaag agaggttaaa tggtataaaa cagaaagatt ttgattcatg
    22681 tacaggagga attaacatga aaaaatttat tatatcaatt atatctttag tattgttttt
    22741 ttcaaatata tcacttatat acaaagtaaa tgctgatgag actaaagtta aaaattataa
    22801 gtttgaaaga gatataacta ttgatggtgt tataggaagt aatagtactt tttttgaagt
    22861 aaataaaaat tgggatattg aagaagtttt attgcatctt aattttagta agagccaaat
    22921 attaaatgga gatgtttcaa gtttaactgt attgataaat aatgtaccaa taaaatctat
    22981 taaattaaat gctaagacaa attataaaaa tacattagaa gtattagttc caaaagatta
    23041 tataattcaa ggatataatg aaataaaaat aaaaacatac aaaacaatat ctgataaaat
    23101 ttgccaagat gattccaata ctgggaactg gatggttatt cacaaagaat catatatatc
    23161 aattagatat aagcagaaaa aggtggaaaa ctcaataaat gaatatccgt atccatatgc
    23221 agaaattgaa aataatcata aattagatac aactatagta gtaccagata atatgactag
    23281 aggagagact acagcagtgt ttaatttggc atcagcattt ggaaaaataa caaaaaatga
    23341 tgatttaaag ttagatgtta aattatattc agaaatgaaa aattggtcag atgataatat
    23401 tatatatatt ggtaaacctg aaaatacagc agaagaaatt ttggatattt taagtataaa
    23461 ggaacaaacc ctattatctt caaactgtat aatcaagcaa gtagattcac catacaataa
    23521 gaataagaag atgatggtgg taattggtag taatgaagat gatttaataa aggcatcaaa
    23581 tttattaata gaaaatagac tttctaacca agttttatca tcatcagtac ttgtaaacaa
    23641 agagactaat ataaaaatta atagggaaca aaaattaaat ttaggtcatt taacattaaa
    23701 agatttagga tattctgact ttttgttgga aggagcattt aatcaacaag ctttgtttga
    23761 tgtcaaaata ccaacgggta aggtattaga tgatggttca aagattatct taaatttaag
    23821 atattctgac aatttagatt ttgaaaaatc tttagttaca gtgtctataa atgatgttat
    23881 tgtgggaagt aaaaaattgg ataggtcaca ttctaataat gataagttag aattaaaaat
    23941 acctaaagat atagataata aaaactatta tcaagttaaa ttgacattta atttgagtat
    24001 aaaaaattcg aattgtgtta ctagagagag taataatcct tgggcatatg tatcaaataa
    24061 ttcttatttg gcgttatcta cgaaagaaaa tgaaacctta tcttttgaaa attatccgta
    24121 tccatttgtt agagatgatg aatttaatga tttaactgtg ataatgccag attattcagg
    24181 gtcacaagct atgacctgga tgtttagatt aggtgttact ttaggtgcga atataaattc
    24241 acataatgga aatataaatg taattagagg aaaagaattt agtgacaagt ataaggatac
    24301 taatattgta gtttttggag tgccacataa taattctgtt ataaagatgt taaataataa
    24361 tttaaatata aagttcgata aaaattactc caattttata tcaaatgata agataagctt
    24421 tattgatgat tatggaaaaa atatttctac tattcaatta ataaaatcac catataataa
    24481 tcaaaaaaat atcatggtaa ttagttcaat gaatgaaaaa aacttatatt taggaatgga
    24541 ttatttgttg aataaaagta aagttaatga tttaaaagga gatacattga taattgatga
    24601 atacggagag gtagaagatt tagcttataa tttaaaatct aagaaagaag taaaagattc
    24661 aagttggaat atgagtataa ataagacaac taaagtattt ttaatgattt cttttattac
    24721 tataattata gtcatgatat tatcaatgct atatataaaa aaatataaaa gaagataata
    24781 tgataaattt attattttaa aagaggtata taatttgagg aaatatatga atgaatttaa
    24841 attaaaaaga agtattttaa tctcattaat aatcttaatt tttatattta tagtttactt
    24901 tgtaagtatt gagttaaaag ataggagtct agtaaataat caatataaag gtaagattaa
    24961 atcggccaat ttatctgtag attatgaaat aaatcaagtt atgaaggata tagataaatt
    25021 gggattgaat acagtaaatg tacctataat tataaatgta gagtccatta attctgatat
    25081 tatgtcaata gataataata gtaaagaaaa ggcaattaag ttaataaaaa aattaaataa
    25141 aaaaggtatt tcaacaatat tagaggcata tccatggatt gaaaatggaa aattgtatga
    25201 gactgactgg aaccctataa ataaaaaaag atttttttat acttggcaaa atgccatatt
    25261 aaatgaactt ataattgatg tagcaaatcc actggatgta aatgttttaa atattggttc
    25321 taattttgta catttggaag aatatcaaca aaattggggt gaaataatag attttgtaca
    25381 atccaaattt gacggtcttg taacgtacag aactaattgg tggtatacaa aaaaagatga
    25441 tttaagtagt aagttgtttt atgaacaaaa gctgaacaat aatttttttg ataagttaga
    25501 ttttatatct atagcagcat attttgagtt aagtaataaa cctgttaata cagtggatga
    25561 attaatttct gccttacact catctactgt aaacaataga ggacaaaata taaaacaaga
    25621 aatatataac ctttataaag ctcatagaaa acctatattt tttggagaat taggtttttc
    25681 aaatagagaa agtgcaagtt ctcagccgtg gaatcatact ccttcaaaag ctgtaaatgg
    25741 cgaagaacaa gcaaggtgtt ttgaggcata taagaaagtt tttgaaaatg aagactggat
    25801 aaatggtttt tctgtgtttt gtgtaggtaa aatagatgac gaaaaaaatt tttacccatc
    25861 aaaagagagt ataaaagtta ttaagtcttg gtatgaataa ttttgaaagt gtagaattta
    25921 tatagattaa atagatgatt aggagagata taaatgaatg acatcaaggt tatgactgta
    25981 tttggaacta gacctgaagc tatcaaagta gcacctttaa taaaggaact tgaaaaaaga
    26041 gagaatataa aaagtattgt ttgcgttaca gctcaacata gagaaatgct tgaccaagtt
    26101 atagaaacct ttaatataaa tgtagactat gatttggata taatggaaaa aggacaaagc
    26161 ctgaatgata taacatgtaa gattttaaat aaacttccct tgattttaaa caaggaaaat
    26221 ccaaatataa tattggtaca tggagataca accacaactc tagctacaag tttgactgca
    26281 ttttataata aaactcttgt tggtcatata gaagctgggc ttagaaccta tgataaatat
    26341 tctccttttc cagaggagct aaatagacaa cttacaggta ttattgctga tatgcacttt
    26401 gctcctacta atttggctag aaaaaacttg atttctgaag gaaaacctaa taataatata
    26461 tttgtaactg gtaatactgc tattgatgct ttaaagatga caataaaaga aaactataat
    26521 catcctataa ttgatgagat tggtaacgat aggatgattt tgttaacctc tcacagaaga
    26581 gaaaatttgg gtaaacctat gaaaaatata ttcagagcta taaagcgaat agtagatgac
    26641 tttgaagatg tacagatagt atatcccata catttaaatc ctaaaatacg aactatagct
    26701 gatgagatat ttggaaaatt tcctgaaaaa attcatatta tagagccttt agatgtagct
    26761 gattttcata actttttaaa taaatcttat atgataatga ctgatagtgg aggaatacag
    26821 gaagaagctc catcattagg taagccagtt cttgtgttgc gtgataaaac agaaagaaca
    26881 gaaggaattg aagcaaagac acttaaatta gtaggtacta atgaagatag aatatataat
    26941 tcagtgagcg atttattaat aaataaagat aactatgttc agatgagtaa agcatctaat
    27001 ccatatggag atggaaatgc aagcaaatat atagtggata taataattaa aaaatttaat
    27061 tgcaaatatt taaattagat aaggcctaaa acattaacta attgatataa gatttatgat
    27121 aatattaagg aatacaattt ttaaggggga gtaatatggc tagaaaatta ataaaaaatt
    27181 tgggtaaaag taaaagtgta aagagagtga aacttttatt taagaagatt tttattactg
    27241 tattcatagt agcaagtata gttgctattt ttaatataac gaaatatttt gaggaattat
    27301 acaaagtaag ggatttaaaa agtactaaaa ttgaatacta tatggatgtg gctgatgaag
    27361 caggagatgg aaaggtccaa ttaagttgga aggccttact tgctatagac atggtaatac
    27421 atgatgaaga tttaagtaat ataaaaaaga aagacacatt ggatataggg gaaaagttta
    27481 tagtagaaga taaaaatggt aaaggcgaaa aggtgtataa ggtaaaaaag tttaataagg
    27541 tattaagcga attgaaattt gactcttctc aaaaaagtag agcaagaaaa tacatgaaag
    27601 atttagaata cacatacctt ggaaataaac aattagatag tagtgatgaa aaaattaaat
    27661 ttataaagaa gttagaagac tcagctataa gagaatatat tgattatgga atattgccct
    27721 ctataacaat tggacaagct atattagaat ctggttgggg aaattctaaa cttacaaaac
    27781 agagtaataa tttatttggt ataaaagcag ataaagcatg gaaaggaaaa agtgtagaaa
    27841 tttcaacttc agagcattat aatgaaaaaa ttgtagctag ttttaggtcg tataattcat
    27901 tacaagattc tgtcaaagac cacagtttat ttttaattaa taataaaaga tatagaaaac
    27961 atgggttgtt tgaggcaaaa gattatatta gtcaagctca agcattagaa aatgcaggat
    28021 atagtacagc agaagataaa aaaggaaatc gtatatatgc agagctatta atagatgtta
    28081 ttaggagtta taatttgcaa ttgatagata ataaagttga gacaaaataa ttgttaactt
    28141 tatatgagga gataacaaga taagattttt ttctacaaaa agaatagaaa aattgtaaaa
    28201 aaaactaaaa aaatgtattg acttgttatt taaaaggtga tattattatt actgtactcg
    28261 aaagagaaca aaa
//
LOCUS       DAYAOO010000051        27580 bp    DNA     linear   BCT 12-OCT-2024
DEFINITION  TPA_asm: Clostridioides difficile isolate ST8-SSI-h139-18
            SAMN40601845-rid21577343.denovo.051, whole genome shotgun sequence.
ACCESSION   DAYAOO010000051 DAYAOO010000000
VERSION     DAYAOO010000051.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN40601845
            Sequence Read Archive: SRR28438827
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 27580)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 27580)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-MAY-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-MAY-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002157583.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002157583.1
            Genome Coverage       :: 163x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/11/2024 16:19:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 4,038
            CDSs (total)                      :: 3,963
            Genes (coding)                    :: 3,930
            CDSs (with protein)               :: 3,930
            Genes (RNA)                       :: 75
            rRNAs                             :: 6, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 60
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 33
            CDSs (without protein)            :: 33
            Pseudo Genes (ambiguous residues) :: 0 of 33
            Pseudo Genes (frameshifted)       :: 7 of 33
            Pseudo Genes (incomplete)         :: 25 of 33
            Pseudo Genes (internal stop)      :: 11 of 33
            Pseudo Genes (multiple problems)  :: 8 of 33
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..27580
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN40601845-rid21577343.denovo.051"
                     /isolate="ST8-SSI-h139-18"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Denmark"
                     /collection_date="2018"
                     /collected_by="Statens Serum Institute"
     gene            2..745
                     /locus_tag="ACGI5H_002407"
     CDS             2..745
                     /locus_tag="ACGI5H_002407"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439973.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MurR/RpiR family transcriptional regulator"
                     /protein_id="HFG9698108.1"
                     /translation="MDGGETMEFYERAKKYEYKFTDTEDMIIEYMRKNKEEIVKLSIQ
                     SLADKFFTVPNTIVRLCKKMEYDGFSQLKNNLKEELKNEDKEPKNGFESDIKKTLELI
                     DYEKINKVADIIQKSRSIIVYGIGQNIPLCEILVKEIRGGHDNITYYSQRHEVLHDIG
                     KLGEQDMFFALSLSGETKEVIEAAKTAVNKGCKVVALTHICENQLQQIADISLYCYST
                     IKQVNGYNISDKVPIMMIMRAIIEQYWLR"
     gene            875..2800
                     /gene="mngA"
                     /locus_tag="ACGI5H_002408"
     CDS             875..2800
                     /gene="mngA"
                     /locus_tag="ACGI5H_002408"
                     /EC_number="2.7.1.195"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728445.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0005351 - carbohydrate:proton symporter
                     activity [Evidence IEA];
                     GO_function: GO:0022877 -
                     protein-N(PI)-phosphohistidine-fructose phosphotransferase
                     system transporter activity [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS 2-O-a-mannosyl-D-glycerate transporter
                     subunit IIABC"
                     /protein_id="HFG9698109.1"
                     /translation="MEFKKITNENLVFLKQKIKTKEDAIKFLARKLYDEGKLTSYEEY
                     LEAVMYRETLSPTGFERGLAIPHGKSKSVKEAAFAAMTLETPIENWESVDPNNKVELI
                     FLIAVPESEGGNTHIQILSELVTRLSNEDYMNMLLNSKTKKELFNNLDIKEKKEQIKE
                     EIRIQNESKKIILAITACPAGIAHTYMSAEALIKAGKEIGVDVYVEKQGANGMVDPHT
                     PDIIKRADAIIYATDVAPKNTERFEHLPNIKTSVAAPLKRAKEIIYEALEVAQKQGKG
                     DYIEKSSDISYCEKSSWKKDVKSAILTGVSHIIPLIVAGGMILAFAVLASQAFGLQEL
                     YNQEGSWLWQLRKLSGGMLGTLMVPVLSAYMSYSLAEKPGLGPGFAAGLAADLIGSGF
                     LGGMLGGLLAGYIVKFLKKNIPAKGTLAGFVSFWVYPVVGSLVVGLLMLFVVGKPVAA
                     LNNGLINWLNGMTGVNAILLGAIIGAMVSFDLGGPINKAAYTFAIGAIASGNFIPYAI
                     FASVKMVSAFGVTIATVLGRDLFSESEKEIGKQTWILGLAGITEGAIPFMIEDPIRVI
                     PSLVAGSAITGSIVAFFNIGLQVPGAGIFSLALLEGSMSGFIIASIWFFAAVLGAIIS
                     AILLIITRKQKNQRKIH"
     gene            2944..5559
                     /gene="mngB"
                     /locus_tag="ACGI5H_002409"
     CDS             2944..5559
                     /gene="mngB"
                     /locus_tag="ACGI5H_002409"
                     /EC_number="3.2.1.170"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728444.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004559 - alpha-mannosidase activity
                     [Evidence IEA];
                     GO_process: GO:0006013 - mannose metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="mannosylglycerate hydrolase"
                     /protein_id="HFG9698110.1"
                     /translation="MKKNVHIVPHMHWDREWYFSTEESRILLVNNMEEIMDMLENNHN
                     YPYYVMDGQTAILEDYLAVKPECKERIKKLVQEGRLIIGPWYTQTDEMVVGGESILRN
                     LLYGIKDCDEFGEYMKIGYLPDSFGQSAQMPQILNGFDIKYSMFWRGCSERKGTNKTE
                     FNWKSDDGSSVLVQILPLGYAIGKYLPMNEDELRTRMDKYLPVLDKGATTDHIILPNG
                     HDQMPIQKNIFEVIYKLKECYPDRKFFLSRYENIFKELEKNEDIDTIKGEFLDGKYMR
                     VHRSIFSTRMDIKSANARIESKITNILEPLASIAYSLGFEYHHGLIELIWKEIMKNHA
                     HDSIGCCCSDKVHQEIMNRFFLAEEKVDQLITFYKRRIVDAMSCEMALDKLIAFNLMP
                     YDRNEIVSAQVITKMKAFEIFDKDNNKLDFEVVHKEVIDAGLIDRQIVHYGNYDSFMV
                     YTINFKDKIPAMGYKAYMIKEVEHMLEKAYEVCDMVDNDFYTIQVNENGTLKIFDKKL
                     NKTFENVLLMENGGDEGDEYDFSPLPNEKLIFNDNIVANSTIKKNRFNNEIKINYRLK
                     VPKDIQARKNNRADSFIDFDIVINVPNDKAIIDVVFNINNQARDCRVRTYIPTNIASK
                     FSVSDNQFGHIKRSVYDDAMEVWQQEDWSERPDSIYPMLTFVGLSDKEHGVAVLTNST
                     REFEIVGEKFDTIAITLFRSVGFLGKEEMARRPGRPSGIKLPTPDSQMIGDIKIDLAI
                     VTHEKSTLEANVANMAKEYLTKIQTYNKMPYNAMKLNQSEIEVDYSYSLLKETNKDLV
                     LSVVKKAEKEEALVVRFYNSKEETKSANIVFNKNIKTAKWINLNEKELESISIDNNSV
                     NVECLMNQVKTILVK"
     gene            5838..6992
                     /locus_tag="ACGI5H_002410"
     CDS             5838..6992
                     /locus_tag="ACGI5H_002410"
                     /EC_number="2.7.1.31"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891405.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0008887 - glycerate kinase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycerate kinase"
                     /protein_id="HFG9698111.1"
                     /translation="MKILISIDSLKGSLSSIEAGNAIKKGILKVKEDAQVKILPLADG
                     GEGTVDALVQGMNGKKETIEVTGPIAKKVDATYGLLKNTSTAIIEIAQASGLTLVPTE
                     LRNPLYTTTYGVGEIIKEAINKGYRNFIVGIGGSATNDAGIGMLQALGFEFYDKNNKL
                     VGLGGKVLNEIRHIKIENRLKELDECKFKIACDVNNPLFGKNGAAYIYGSQKGATSEI
                     IEKLDNGLRNFSKVVKNYLSKDVANVEGAGAAGGLGFAFLAFLDSKLESGIKIILEEI
                     KLEEELKDADFVITGEGRLDNQTAMGKAPIGVAKLAKKYGVKVIGLAGATTEDAVKCN
                     EEGIDAYFSIVNRAMTIEEAMDKATASENMTATTTQIFNLITSIQQSKNM"
     gene            complement(7115..9028)
                     /locus_tag="ACGI5H_002411"
     CDS             complement(7115..9028)
                     /locus_tag="ACGI5H_002411"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903449.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HFG9698112.1"
                     /translation="MKTSKKELFLNFIKTQHDWIDSSTLANYLNVSTRSIRKYVNEIN
                     SNGAFILSSKKGYKVNLNTNCQTKIDSSENISPDNRLNLILKELIVNSNGINIFDLSE
                     ELFVSPATIEGDIVKANKFIGSYNLKIKQSKFLLKLVGNESAKRKLMSSIIFKETGSD
                     FLSLFDVQKIYQEYNLTKLKENIIYILKKYNLFINEYAINNILLHLMITIDRIKKNNY
                     IDSVEVVNYIDNNVDINIAKDISNFLESEYNITLTSAELYYLVFQLTNKTTVLNYNQM
                     DTKSLSNYIDEHFVKLTKKIIKNVYDLYLIDLSDEEFVVKFTLHVKNLISRAKNNQVL
                     RNQIPQKLKDSYPLIYDISVYICNQIQTLENVDIDEDEISYISLHVGSFFDRQKLLED
                     KVLCALITPNYYDLQFKIVRDLEKRFNESIEIIQIFSDTHNLDFDNKVDMVITTLPIN
                     DRCPIPFVYVNPYLNRKDYDNIQSKFIQIKDRKNILTVQNHLEMYFSESLFMKNIYLD
                     SAKDYIRFMGNILYENKYVKPNYIDDVLIREKMSSTAFNNNVAIPHSMKMDALKTGVC
                     LIVNDKPVKWGEEKVQIIAMIPINEKEKEKFNYIFESFIEILSEWNNVKELTKADNYS
                     SFMNRIAYLIQNI"
     gene            9270..9587
                     /locus_tag="ACGI5H_002412"
     CDS             9270..9587
                     /locus_tag="ACGI5H_002412"
                     /EC_number="2.7.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891401.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HFG9698113.1"
                     /translation="MKNIRVLLACGSGASTGFMATSMRKSAKKKGIEADIKARSESEI
                     DKYLSEIDCLLLGPHLDYMKEEIQQKANEYNVPVACISKTAYGRLDGAKALEEALELI
                     SNK"
     gene            9610..10842
                     /locus_tag="ACGI5H_002413"
     CDS             9610..10842
                     /locus_tag="ACGI5H_002413"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898150.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HFG9698114.1"
                     /translation="MNKFIDFLSEKFTPVVNNMTKNIWVQSVQSTIMKVLPMVFVGSL
                     VTIVSVLKNYISFLPDLSPINQYTFGLLGLFIAFLLPMETMKNKKFESMSVVAGLAGA
                     GLMLMMIRPEITNEGAIFNFNRFGGEGMLVSLVAGLFSGLIMSLFGSFSFFGEDSALP
                     DFVSKWFDNMLPITVIMFVGWGLIYGLNFDMFEIIVRVFKPVSDIAQTLPGFVLLNFL
                     VVFIYSLGISGWVLSPITYSIQLGAIAANAAAVASGGVATNIYVYEVIQTGWITLGGL
                     GATLPLVIMMCLSRVGRIKAIGRACIVPSIMNINEPVIFGAPVAWNPFLMLPMWIGTV
                     VISITTYLSMSMGFVTIPSKVFNLWYVPFGISTFMVNQDVRGLIVLAINIVLLFMIWY
                     PFFKAYEKEEIKLESQEV"
     gene            10871..11224
                     /locus_tag="ACGI5H_002414"
     CDS             10871..11224
                     /locus_tag="ACGI5H_002414"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891397.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose/cellobiose transporter subunit IIA"
                     /protein_id="HFG9698115.1"
                     /translation="MTIEEHIIDEELVEVAMQIILRAGEARTEIKHALNDLEKFDYRN
                     ADLKLAKAKGFMTEAHRAQTKIIQGEAGGEKRAHSLLFAHAQDTLMTIFSELNITMSL
                     VGIVKSIEYKVNNSK"
     gene            11246..12691
                     /locus_tag="ACGI5H_002415"
     CDS             11246..12691
                     /locus_tag="ACGI5H_002415"
                     /EC_number="3.2.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427245.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016798 - hydrolase activity, acting on
                     glycosyl bonds [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
                     /protein_id="HFG9698116.1"
                     /translation="MIKLGKFPKGFLWGGAVAANQLEGAWNEGGKGWCLADVHMYDKD
                     RDISKPYESDMTIERIKFAMKDNNGYYPKRSGIDFYHTYKEDLKLLKELGLKCFRFSI
                     NWARIFPNRDDLEPNEEGLKFYDNLINEVIDNGMEPIVTLLHYETPLNLVLKYKGWSN
                     RKVVDFFVRYAELILNRYKNKVKYWIVINQINLIHYESFNSVAFCVDQVDNVEETRYQ
                     AIHHQFIATALTKKLGKEINSDMMIGMMMADCTSYPEDCDPENVVFALKRNRLQYFFT
                     DVSFRGEYPVYIKRFFKENNINIVMEEGDDKILKENTMDFLALSYYYSTTVSASKNTM
                     NPTDNIKNPYLKANPWGWAIDPKGLYNTLSQYYDRYQKPIMIAENGFGMHDKFEDGKV
                     HDSYRIDYLGKHIEQIGEAIADGTEILAYCMWSPIDIVSCSSQEMEKRYGFIYVDIDN
                     NGNGSKERYKKDSFYWYQNVIRTNGEELREK"
     gene            13083..13835
                     /locus_tag="ACGI5H_002416"
     CDS             13083..13835
                     /locus_tag="ACGI5H_002416"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427244.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MurR/RpiR family transcriptional regulator"
                     /protein_id="HFG9698117.1"
                     /translation="MIIELNKSNSENLTKTELEIIKFINENESILPELSIVEIAHETY
                     SSPATVSRAIRKCGLNGFNELRYRLTVKDENDDIQNMGDIINKSFIEAQRVIEQISLT
                     TLINIIKTINKSSKIYILARGLTEYVAKEFSLKLQLLDFNVVFINDPNIMKIKSKSIK
                     KDELIIIFSLNGNTIELVESAQNANLVGAKVITCCCSESAKLIKYSDLYIVGYKHEHI
                     SISEYEVSSRLPLYIISRIIIDYMVRYNNSEN"
     gene            13937..14857
                     /locus_tag="ACGI5H_002417"
     CDS             13937..14857
                     /locus_tag="ACGI5H_002417"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009906218.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1-phosphofructokinase family hexose kinase"
                     /protein_id="HFG9698118.1"
                     /translation="MIYTLTTNPAIDMNISTNGIKRKLVNRTSNAVYSPNGKGLNVTF
                     VLGHYGIESKILGFFGGFSGKYIVEESEKRGFDVLPTWVEDTTRINIFLNDGSDEFKF
                     VNSGSYVNEKQKLDMLDKIQSLADISYLSISGSLPPGIDDNYYEDIFKICKNKSIKTI
                     LDISSPKLKELLQYNPYLIKPNDEEIKDIFGIIVRDEEDIKDVLKLLHLKGAQNILLT
                     LGEKGSYFYNGKSIYYASAQPVTVVSSACAGDSALAAFLSIWLENPEHIEEALKRSAA
                     TGASVAESNGIGNLENVEDYIKNIRVRKVV"
     gene            14860..16776
                     /locus_tag="ACGI5H_002418"
     CDS             14860..16776
                     /locus_tag="ACGI5H_002418"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439955.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0022877 -
                     protein-N(PI)-phosphohistidine-fructose phosphotransferase
                     system transporter activity [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="fructose-specific PTS transporter subunit EIIC"
                     /protein_id="HFG9698119.1"
                     /translation="MGKKMILGVTGCPTGIAHTFMAEEALKNSARELGCDIKVETNGA
                     IGVENKLTAKDIEMADAIIVACDKNVDMDRFNGKPVIEVPVKEGIHKANELIQRCIDG
                     KVAIRKGNLSSSKIAEEGNLSFGQKLYKDLMNGVSHMLPLVVAGGVLTAISFLWGIYS
                     FDPNSEQYNQIAATLKSVGGYSMNLMVPVLAAFIAQSISGRAGMLAGLVGGMISFDTG
                     SGFLGGIISGFLAGYLVKLFVHLLRKLPRQLEGLKSIFIIPIVSVGLVGVAMLLLGGP
                     CSALNNAMMNFLSGLQNSSPIILGIVIGCMSAFDMGGPVNKAAYVTGTMLLGQGNYLF
                     MAGVSAACITPPLVIAIASTLFKNRFTEEDRAAGLINYILGSTHITEGAIPFAAKNPL
                     KVLPVLMIASSISSILTYIMKIEVPAPHGGFLVLGLVNKPLLWVGCIFVGSLVGAVLY
                     MMVTPKVVNEKNTIENTNVTKDEHKNESAESENVSNNISLYSEETVILDVKGKNKTDV
                     IDEMIGILDKSSVLLDKKKFKEEILKREEISSTGFGMGIAIPHAKTDAVKVPRVAVGV
                     SKEGFDFESEDGSLAHIIFMIAATDNGDNLHLKTLSQLSSKLMNEEFLNELLNSKTSR
                     EIVAKLNNEEIKSV"
     gene            16796..17665
                     /gene="gatY"
                     /locus_tag="ACGI5H_002419"
     CDS             16796..17665
                     /gene="gatY"
                     /locus_tag="ACGI5H_002419"
                     /EC_number="4.1.2.40"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439953.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tagatose-bisphosphate aldolase subunit GatY"
                     /protein_id="HFG9698120.1"
                     /translation="MALVTTKQILLDAQEGHYAVGAFNVENMEMVMAVIEAAEELKSP
                     VILQTTPSTIKYAGLDYYLANVKVASEKASVPVAMHLDHGSSFGLAMQALRVGYTSIM
                     IDGSHESYEDNISISKSVVDACMPSDIPVEAELGKVGGKEDDLDGGDGGAYTDPLEAK
                     EFVERTGVSSLAVAIGTAHGLYKGEPKLDLDRLSEIRDVVSVPLVLHGGSGIPDEVIK
                     ESIKRGICKVNYATELRIAYSNGVKDVLNSDPEVIDPKKYGKKGLESVKDFVKSRMEV
                     CGCVGKAIEIVKC"
     gene            18175..19638
                     /locus_tag="ACGI5H_002420"
     CDS             18175..19638
                     /locus_tag="ACGI5H_002420"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0008170 - N-methyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="N-6 DNA methylase"
                     /protein_id="HFG9698121.1"
                     /translation="MITGELRSKVDKIWETFWTGGLTNPLEVIEQFTYLLFIKGLDEV
                     ETKNEAEATLLGVSFERIFDDEHQHLRWSKFSNEGNSEKMYEIVQNEVFPFIKKLHGN
                     KDSAYAKYMGDAIFKIPTPLMLSKIVDGISNLELSKDRDTKGDLYEYLLSKVATAGTN
                     GQFRTPRHIIDMIVRLIKPTPEDIIVDPAAGSAGFLVSSQQYLRDNHSSLFLVQGLKE
                     HFNNGMFYGFDMDRTMLRIGAMNMMLHGVDNPNIEYKDSLSEVNTDKDKFTLVLANPP
                     FKGSLDYEAVSADLLKVTKTKKTELLFLALFLRVLKIGGRCACIVPDGVLFGSTGGHK
                     SIRKEIVDNHKLEAIISMPSGVFKPYAGVSTAIMIFTKTGTGGTDKVWFYDMKADGYS
                     LDDKRNEIKDSDIEDIIKRFDNLDGEVDRKRTEQSFFVDVEEIRENGYDLSINKYKEV
                     VYEEVVYDAPSVIIGRVRELEKEIAVGLEELERMLEV"
     gene            19642..20814
                     /locus_tag="ACGI5H_002421"
     CDS             19642..20814
                     /locus_tag="ACGI5H_002421"
                     /EC_number="3.1.21.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903440.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006304 - DNA modification [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="restriction endonuclease subunit S"
                     /protein_id="HFG9698122.1"
                     /translation="MEYIKLNELCYINIGKTPSRNTSDYWGSGNRWLSISDLKEKYIS
                     KSKEEITDLAVEKANMKLVPKNTVVMSFKLSIGRVAILKEDMFTNEAIANFQIKNNEL
                     ITSEYLYYALRTLNFNNTDRAVMGATLNKSKLNDIKIPYFTICIQNKMVEVLNKAQEL
                     INKRKEQIEALDELVKSRFIEMFGEPINNTKKFDMKKIKEISIYLKRGVSPKYVEQSN
                     IKVINQKCIYWRNLKVENCKYYDENLKEKIEDIFLKQNDILINSTGTGTLGRCVKFNK
                     IDNSEYIADSHVTVLRSISNNLNSDYFAALFEFTNIQDTIYRKCVNGSTNQIELSVSK
                     LGEYLIMVPPIEFQNQFSEFVKQVDKLKLKIETNLKELEDNFNSLMQKAFKGELFN"
     gene            20847..21227
                     /locus_tag="ACGI5H_002422"
     CDS             20847..21227
                     /locus_tag="ACGI5H_002422"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439944.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016779 - nucleotidyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotidyltransferase domain-containing
                     protein"
                     /protein_id="HFG9698123.1"
                     /translation="MRNIPNEIKNSIINVFPKENTLAIIIFGSYGTDKHTSESDIDIA
                     WIPIKKVPITELATKTEALRNILDIDVDLKIVTDNYTIALKKAILEGEVIYESKDFKD
                     YINKFYFENSDVIDILDWRDMYGN"
     gene            21217..21645
                     /locus_tag="ACGI5H_002423"
     CDS             21217..21645
                     /locus_tag="ACGI5H_002423"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427232.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9698124.1"
                     /translation="MVIRNKLSWNSIEEVNRDFGSCLYDLQNFKILYDKEEMPELWAR
                     YIKEGFKSYMVSFLELTKAMLYYKSIDLNIKSKNFYDYLLACEYHNLLPKNSSIVIET
                     LRKLRNDDSHGYDIPQFEDMYELFTENEEVFVSIRNSCKK"
     gene            21695..25030
                     /locus_tag="ACGI5H_002424"
     CDS             21695..25030
                     /locus_tag="ACGI5H_002424"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439941.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase family protein"
                     /protein_id="HFG9698125.1"
                     /translation="MGNFDFLQKKKNFNSFNTACLEAEKSILVSPSTCATITRRALEL
                     AVKWLYANDSDLVLPYQDNLSTLIHNNSFIELIDYDMLPLLKYIVKLGNLSVHTSANI
                     ERGEAILSLNNLHQFVSWIDYCYSDEYTAEDFNEDLLLHGEEKRTRPDELKNLYERLS
                     SKDKKLEEVIKENEELRKSLTEKRKVNTVNYDFKIDEVSEFETRKRYINIELKLAGWE
                     FGKDIGEEIEVQGMPNESGVGYVDYVLYGENGKPLAVVEAKRTSKDPKIGQQQAKLYA
                     DCLEKRYSQRPVIFLTNGFDMYIWDDYSDRKVYGFYKKSELQLMMDRRKSKKSLSSVT
                     INDEISNRYYQKEAIRAVCEALENKQRKTLLVCATGTGKTRIAISIVDVLSRHNWIKN
                     ILFLADRKALVKQAKKSFTKLLPNLALCNLLDSKDSPEDARMIFSTYPTMMNAIDDTK
                     SKDGKRLFTPGHFDLIIIDESHRSIYKKYKSIFDYFDSYLMGLTATPKDEIDKNTYSV
                     FDMENGVPTYAYEYNKAVEDGYLVDYTSIEFKTKIMEDGIKYDELSDEEKEEYENTFN
                     DDESIGDEIGNNAVNEWLFNSDTIDLVLNKLMTEGLKIEGEEKIGKTIIFAKNTKHAR
                     AIVERFNKLYPKYGGNFVKAVDYSINYVDSIIDDFSDKNKLPQIAVSVDMLDTGIDIP
                     EILNLVFFKKVRSKTKFWQMIGRGTRLCPDLLGVDMDKERFLIFDFCNNFEFFKFNPK
                     GFEGNKAETLTEKLFNIKVSMVKELQDIKYIEGEYAELRKELLEELITSVKALNEDSY
                     IVRMNLSYVHKYKNENVWSNIGAVAQNEIREYISPLITSYSDDELAKRFDVVMYNIQL
                     AYLQNNNASKGIRHVMATAEKLSKLGTIPQIQQQKYTIEKAMTENFWEDSDIFEVEEV
                     RISLRELIKYLEKSSQKIYYTSFEDMIVAEDRNDSVYNANNLKNYKKKVEYYLNSHKD
                     ELAIFKLRNNKKITKQDVETLEEILLKQLGNCDDYKKEFGDTPVSQLVRRLVGLDREA
                     ANEAFSEFLNNKSFNTKQIHFVKLIVDYVVKNGFIEDNKVLMEDPFRTVGSIIDLFEN
                     HIEERNKLIKTINKIKENASEIG"
     gene            25411..27474
                     /locus_tag="ACGI5H_002425"
     CDS             25411..27474
                     /locus_tag="ACGI5H_002425"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439939.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF262 domain-containing protein"
                     /protein_id="HFG9698126.1"
                     /translation="MKAGEIEFLSYLEGSNKSFVVPVYQRNYNWKKEQCKRLFDDLED
                     IIDSGFRTHFLGSVVSIYSMGKEYLIIDGQQRVTTVSILLIAMCQIIKEFGESKGIIT
                     TEEQIKECYLINKHSRDKDGKIKLKPIAEDRKAYYELFEEEMNTDRNSNIVSNYLYFY
                     NRIKEDNISIDDLFDAIQKLTIVEIELKNGEDDPQLIFESLNSTGLDLSEADRVRNFV
                     LMGRSSKLQEEFYNNYWYKIEKNTSSNVSSFIRDYLTIKERSIPNKNKVYFSFKRYVS
                     DNGIDIEILLKDLLKFSNYYREISYSCTDDNDVNKVLKRINKLEIFVSYPFILELFDD
                     YNEGIINKKVLVESLNLVECFILRRIVCDVPPNALNKVFMNLGREIKKFSDYKENYSN
                     ILRYIFINKKSSQRFPTDSEFSNAFETKDIYNTKSKNKLYILERLENYSNKEIVDLEN
                     LINNNMLNIEHIMPQTLTNKWKESLGDNYKEIHDKYLHTIGNLTLTGYNSKLSNKTFE
                     EKKEMEDGFKDSRLYLNKYISSIDKWNEEEIKNRTKILLDRAVEIWKYPSVTYEPPSN
                     SENIFTLEDDDVNFTNESIVSFSILGESYKAKNWTEFYEQVALTLYDLDSVRFNSIVD
                     KTYKRDFIDNIKSRDAYKLRKGIKISENIYLETNLNTEAKLNIIRFLLNEFDIELNEV
                     IFSIK"
BASE COUNT        10957 a         2827 c         5061 g         8735 t
ORIGIN      
        1 aatagatgga ggagaaacta tggaatttta tgaaagagca aaaaaatatg agtataaatt
       61 tacagataca gaagacatga taattgaata tatgagaaaa aacaaagaag aaatagtaaa
      121 attatcaata caatctttag cagataaatt ttttactgtc ccaaatacca tagttaggct
      181 atgtaaaaaa atggagtatg atggtttctc tcaactaaaa aataatttaa aagaagagtt
      241 aaaaaatgag gataaagagc caaaaaatgg ttttgaatca gatataaaaa agacattaga
      301 gctaatagat tatgaaaaaa taaataaagt agcagatata attcaaaaat ctaggagtat
      361 tatagtttat ggaataggtc aaaacattcc tttatgtgag atattagtaa aagaaattag
      421 aggtgggcat gataatataa cttactatag tcaaagacat gaagtacttc atgatatagg
      481 aaaattaggt gaacaagata tgttttttgc acttagttta agtggagaaa cgaaagaagt
      541 tatagaagca gcaaagacag cagttaataa gggttgtaag gtagtagctt taacacatat
      601 atgtgaaaat caattgcaac aaattgcaga tataagttta tattgctatt caacaattaa
      661 acaagtaaat gggtacaata tatcagataa ggttccaatt atgatgatta tgagagcaat
      721 aatagagcaa tattggttaa gatagagatt tgtgtataaa tacacaaatc tttatttttt
      781 aagaagaaat tgtgtgtata atttcaaaaa aacattttca taatttattt tatgctatat
      841 tcatagcatt aaatgattta aggagggcgt aattttggaa tttaagaaaa tcacaaatga
      901 aaaccttgtt tttttaaaac aaaaaataaa aacaaaggaa gacgcaataa agttcttagc
      961 aagaaagcta tatgatgaag gcaagttaac atcttatgag gaatatttag aagctgtaat
     1021 gtacagagaa actttatctc caacaggttt tgaaagaggg cttgcaattc ctcatggaaa
     1081 atctaagtca gttaaagaag ctgcatttgc agctatgacc ttagagacac caatagaaaa
     1141 ttgggaaagc gtagacccaa ataataaagt agagctaata tttttaatag cagtaccaga
     1201 aagtgaaggt ggaaatacac acatacaaat actttctgag ttagttacta gactgtcaaa
     1261 tgaagattat atgaatatgt tgttaaattc aaaaactaag aaagagttat ttaataactt
     1321 agatataaaa gaaaagaaag aacaaataaa agaagagatt aggattcaaa atgaatcaaa
     1381 aaaaattata ttagcaataa cagcatgccc tgccggtata gcacatacat atatgtcagc
     1441 agaagcatta attaaagctg gtaaagaaat aggtgtggat gtgtatgtag aaaagcaagg
     1501 agctaatggt atggtggacc ctcatacgcc agatataata aaaagggcag atgcaataat
     1561 atatgcaaca gatgtagcac ctaaaaatac agaaagattt gaacatttgc caaacataaa
     1621 aacgtcagta gcagctccac taaaaagagc aaaagaaata atatacgaag ctttagaagt
     1681 agcacaaaaa caaggtaaag gtgattatat agaaaaatca tctgatatat catattgtga
     1741 aaaatcatca tggaaaaaag atgtaaaatc agcaatactt acaggagtat ctcatataat
     1801 accacttatt gtggcaggag gtatgatact tgcatttgca gtattagcat ctcaagcatt
     1861 tggtctacaa gaactataca atcaagaagg ttcttggtta tggcaattaa gaaagctttc
     1921 tggaggtatg ttaggtacat tgatggttcc agtattatca gcatatatgt cttactcact
     1981 agctgaaaaa ccaggtcttg gaccaggatt tgcagcaggt ctagcagctg atttaatagg
     2041 tagtggattt cttggaggta tgttaggagg tttacttgct ggttatatag taaaattttt
     2101 aaagaagaat ataccagcca aaggcacatt agctggattc gtaagttttt gggtatatcc
     2161 agtagttggt tctttggtag taggtttatt gatgttattt gtagtaggaa agcctgtagc
     2221 agcacttaac aatggtctta taaattggtt aaatgggatg actggagtaa atgcaatact
     2281 actaggtgca ataataggag ctatggtttc atttgactta ggtggaccaa taaataaagc
     2341 agcctataca tttgcaatag gagcaatagc aagtggaaat tttatacctt atgcaatatt
     2401 tgcatcagtt aagatggttt cagcttttgg agttacaata gctactgttt taggcagaga
     2461 tttattttca gaatcagaaa aggaaatagg aaagcaaact tggatattag gattggctgg
     2521 aataactgaa ggtgcaatac catttatgat agaggaccca atccgtgtta taccatcatt
     2581 ggtagctggt tcagccataa ctgggtctat agtagcattc ttcaatatag gtcttcaagt
     2641 gcctggagcg gggatattct cattggcgct tttagaggga agtatgtcag gatttattat
     2701 agcatcaata tggttctttg cggcagtact tggagctata atatcagcaa tattattaat
     2761 aataactagg aaacaaaaaa atcaaagaaa gatacattaa aagatacgtt attagatatt
     2821 taaatcaaag gtttaattat agtgataaaa taaatattaa aaaattttgt aaactcagta
     2881 gtatttttat tggattttta attagacaga aaatattatc agataagttt tggaggataa
     2941 gcaatgaaaa aaaatgtaca catagttcct catatgcatt gggatagaga atggtacttc
     3001 tcaactgagg aatctagaat attacttgta aataatatgg aagaaataat ggatatgtta
     3061 gaaaataatc ataactatcc atattatgtg atggatggtc aaactgctat attagaagat
     3121 tatttagcag ttaagcctga atgtaaggag agaataaaaa aattagttca agaaggaagg
     3181 ctaataatag gtccttggta tactcaaact gatgaaatgg tagttggtgg agaatccata
     3241 cttagaaatt tactatatgg aataaaagat tgtgatgaat ttggagaata tatgaaaata
     3301 ggatatttac cagattcatt tggtcaaagt gctcaaatgc cacaaatact aaatgggttt
     3361 gatataaaat attcaatgtt ttggagagga tgttctgaaa gaaaaggaac taataaaaca
     3421 gagtttaatt ggaagagtga tgatgggtct tctgttttgg ttcaaatact tccattaggt
     3481 tatgcaatag gaaaatatct accaatgaat gaagatgagc taagaacaag aatggataaa
     3541 tatttaccgg ttcttgataa gggtgcaact actgaccata taatacttcc aaatggacat
     3601 gaccaaatgc caattcaaaa gaatatattt gaagttatat ataaattaaa agaatgttat
     3661 ccagacagaa aatttttctt aagtagatat gaaaacatat ttaaagagct agaaaaaaat
     3721 gaggatatag atacaataaa aggggaattt ttagatggga aatatatgag ggttcataga
     3781 agtatattct caacaagaat ggatataaaa tcagcaaatg ctagaataga atcaaagata
     3841 actaacatat tggagccact agcttctatt gcatattctc taggatttga atatcatcat
     3901 ggattaatag agttaatttg gaaagaaata atgaaaaatc atgctcatga cagcattgga
     3961 tgttgttgtt cagataaagt tcaccaggaa ataatgaata gatttttctt agctgaggaa
     4021 aaagtagacc aattaataac attttacaaa agaagaatag ttgatgcaat gagttgtgaa
     4081 atggctttag ataagttaat agcatttaac ttaatgcctt acgataggaa tgaaatagtg
     4141 agcgcccaag ttataactaa aatgaaagca tttgaaatat ttgataaaga taataataag
     4201 ttggattttg aagtggtaca taaagaagta atagatgcag gattaataga ccgtcaaatt
     4261 gttcattatg gaaactatga ttcatttatg gtatatacaa taaactttaa agataaaata
     4321 cctgcaatgg ggtataaggc gtatatgata aaagaagttg aacatatgtt agaaaaagct
     4381 tatgaagtat gtgacatggt agataatgac ttttatacta ttcaagttaa tgaaaacggg
     4441 acattaaaga tatttgataa aaaattaaat aaaacttttg aaaatgtatt attgatggaa
     4501 aatggaggag atgaaggaga tgagtatgat ttttcaccac ttccaaatga gaaattaata
     4561 tttaacgata atatagtagc aaattccact ataaagaaaa atagatttaa taatgagata
     4621 aagataaatt atagattaaa agtaccaaaa gatatacaag ctagaaaaaa taatagagca
     4681 gattcattta ttgactttga tatagttata aatgttccaa atgataaagc tataatagat
     4741 gtagtattca acataaataa ccaagcaaga gattgtaggg ttagaactta tataccaaca
     4801 aatatagctt caaagttttc tgtgtctgat aatcagtttg gacatataaa gagaagtgtg
     4861 tatgatgatg ctatggaagt ttggcaacag gaagactgga gtgaaagacc agattctata
     4921 tatccaatgc taacattcgt tggattgtct gacaaagagc atggagtagc tgttcttaca
     4981 aacagtacaa gagagtttga aatagtaggg gaaaaatttg acacaatagc tataacatta
     5041 tttagaagtg taggattcct aggtaaagaa gaaatggcaa gacgcccagg tcgtccatca
     5101 ggaataaagt tgcctactcc agattctcaa atgataggag atataaaaat agacttagca
     5161 atagttactc atgaaaaatc tacactagaa gcaaatgttg caaatatggc taaagagtat
     5221 ttaacaaaaa tacaaactta taataaaatg ccatataatg ctatgaaatt gaatcaatca
     5281 gaaatagaag tagattattc atatagttta cttaaggaaa ctaataagga ccttgtgtta
     5341 agtgttgtaa aaaaggctga aaaagaagag gcattagtag ttagatttta taattctaaa
     5401 gaagaaacaa aatcagctaa catagtattt aacaaaaata ttaaaacagc taaatggatt
     5461 aacctaaatg aaaaagaatt agaatctata tcaatagata ataactctgt aaatgtagag
     5521 tgcttaatga accaagttaa aactatactg gttaaatagt gctaaaaatg attagatagt
     5581 gctaaaaagg aattatctta aaatagagat aatcctcctt atcattgttg aaataataaa
     5641 catatatttg attttataca aaagagtgtc tcatgaacta agaaatttat tttgagacac
     5701 tcccttttta taagataaaa gaatattaat ggtataagtt gtatacaaag agagatgtag
     5761 agtataaaat aaaagataaa ttaagcttat aaaattatat gtttaaaata aggagtaata
     5821 aaaaggagta gataagtatg aaaatattaa tttctataga ttctttgaaa ggaagcttat
     5881 cttcaataga ggcaggaaat gcaataaaaa aggggatatt gaaggttaaa gaagatgcgc
     5941 aagtaaagat attgccactt gctgatggtg gtgaagggac agtagatgct ttagttcaag
     6001 ggatgaatgg taaaaaagag actatagaag ttactggacc aatagctaaa aaagtggatg
     6061 caacatatgg attattaaaa aatacaagta cagcaataat agaaatagct caagcatcag
     6121 gattaacatt ggttccgact gaacttagaa atcctttata cactacaact tatggtgttg
     6181 gggaaataat aaaggaagca ataaataaag gctatagaaa ttttatagtt gggataggtg
     6241 gaagtgctac taatgatgct gggataggta tgcttcaagc cttagggttt gagttttatg
     6301 ataaaaataa caagttagta ggattaggtg gaaaagtttt aaatgaaata agacatataa
     6361 aaatagaaaa tagattaaag gaattagatg aatgtaagtt taaaatagcc tgtgatgtaa
     6421 ataatccgct gtttgggaaa aatggagctg catacatata cgggtctcaa aaaggtgcaa
     6481 catcagaaat aattgagaag ttagataatg ggcttagaaa tttttccaaa gtagttaaaa
     6541 attacttaag taaagatgta gctaatgtag aaggagcagg agcagcagga ggattaggtt
     6601 ttgctttttt agcattttta gattcaaaat tagaatctgg aataaaaata atattagaag
     6661 aaattaaatt agaggaagag ttaaaagatg cagattttgt cataactggt gaaggtagat
     6721 tggacaatca aactgctatg ggcaaggctc caataggagt tgcaaaactg gcaaaaaaat
     6781 atggggtaaa agtaataggt ttggctggag ccacaacaga agatgcagtt aaatgtaatg
     6841 aagagggtat agatgcttat ttttctatag taaatagagc tatgacaata gaagaagcaa
     6901 tggataaagc aactgctagt gagaatatga cagctacaac aacacaaata ttcaatctta
     6961 taactagtat acaacagtca aaaaatatgt agtattaaaa caaggtatat taggtaaaaa
     7021 gctgtcacat attaatttag actttttagt gtgacagctt atctatttta tgttaataac
     7081 ttaagaaaca tatattggaa ataaattaat ggatttagat attttgaata agataagcta
     7141 ttctattcat aaaactacta tagttatctg ccttagtaag ttctttaaca ttattccatt
     7201 cagataatat ttcaataaag ctttcaaata tgtaattgaa tttttctttt tctttttcat
     7261 ttataggtat catagctata atttgaactt tttcctcacc ccatttaact ggtttatcgt
     7321 taacaattaa acatactccg gtttttaaag catccatttt catgctatga ggaattgcta
     7381 cattgttatt aaatgcagtt gaagacattt tttctcttat aagaacatca tctatataat
     7441 tgggtttgac atatttattt tcgtacagaa tatttcccat aaatcttata taatctttag
     7501 cactatctaa atatatattt ttcataaaca aagattcact aaagtacatt tctaaatgat
     7561 tttgtacagt aagtatattt tttctatctt taatctgaat aaatttactt tgaatattat
     7621 cataatcctt tctatttagg taaggattta cataaacaaa aggtataggg catctatcgt
     7681 taattggtaa agtagtaata accatgtcta ccttattgtc aaaatcaaga ttatgagtat
     7741 ctgaaaaaat ctgaataatt tctatggatt cattaaatct cttctcaagg tctcttacta
     7801 ttttgaattg taaatcatag taatttggag taattaatgc acatagaact ttatcttcta
     7861 ataatttttg tctatcaaag aatgaaccta catgaagaga tatataagat atttcatctt
     7921 cgtctatatc tacattttct aaagtttgaa tctgattgca aatataaaca gatatatcat
     7981 atatcaaagg gtaggaatct tttaactttt gaggtatttg atttcttaaa acttgattat
     8041 ttttggctct actgattaaa ttttttacat gaagagtaaa ttttacaaca aattcctcat
     8101 cagataaatc tataagatat aagtcatata catttttaat tattttttta gttaatttaa
     8161 caaagtgttc atctatataa tttgacaatg atttagtatc catttgattg tagtttaaga
     8221 ctgtagtttt gtttgttaac tgaaatacta aatagtataa ttccgcacta gttaaagtta
     8281 tattgtattc agattctaaa aaatttgata tgtcttttgc aatatttata tctacgttat
     8341 tgtctatgta gtttactact tcaacagagt ctatgtaatt attctttttt attctgtcta
     8401 tagttatcat taaatgaaga agtatgttgt ttatagcata ctcatttata aataaattgt
     8461 atttttttaa tatatatatt atattttctt ttagtttagt caaattatac tcttgatata
     8521 ttttttgtac atcaaataag cttaaaaaat cacttcccgt ttctttaaat attatagagc
     8581 tcattaactt gcgctttgca gactcatttc caactagttt caataaaaat ttcgattgct
     8641 ttatctttaa attataactt cctataaatt tattagcttt gactatatcc ccttcaatag
     8701 tagctgggct aacaaataat tcttcactta aatcaaatat attaattcca ttactattaa
     8761 ctataagttc ttttaaaatt aaatttaatc tgttatcagg tgatatattc tctgaactat
     8821 caatcttagt ttgacaatta gtattgagat ttactttata gcccttttta gaagataata
     8881 taaatgcacc attagaatta atctcgttta catattttct aatcgaacgt gttgatacat
     8941 taaggtaatt agctaatgtg gatgaatcta tccaatcatg ttgcgttttt atgaaattta
     9001 aaaatagctc ttttttagat gttttcatta gattccctcg catagtttta aaataaaatc
     9061 tgtatgatat gataattata taattgaatg tacgtattat aagatacatt atactatatt
     9121 aataggtcta attaagagta aatgatttcc tattattagg aaatatattt atgtgaaatg
     9181 aacttatttg ggaagtaaaa tataaacata ataaaataaa aagttcatta agaaataaat
     9241 taatggataa aaatattgga ggtattatta tgaaaaatat aagagtgctt ttggcgtgtg
     9301 gttcaggagc aagtacaggt tttatggcaa ctagtatgag aaagagtgca aagaaaaaag
     9361 gtatagaagc agatataaaa gcgagaagtg agtcagagat agataagtat ttatcagaaa
     9421 tagattgttt attactagga ccacatttag attatatgaa ggaagaaatt caacaaaagg
     9481 ctaatgaata taacgttcca gtagcatgta tatctaaaac tgcatatgga agactagatg
     9541 gtgcaaaggc tttggaagaa gcactagaac taatatcaaa caaataaaat atttatgggg
     9601 agagtgttta tgaataaatt tatagatttt ttaagtgaaa aatttactcc tgttgtaaat
     9661 aatatgacta agaatatatg ggtacaatca gttcaatcaa ctataatgaa agttttgcca
     9721 atggtatttg taggctcatt agtaactata gtttctgtct tgaagaatta cataagcttt
     9781 ttacctgatt taagtccaat aaatcaatat acatttggac ttttaggatt atttatagca
     9841 tttttattgc ctatggaaac aatgaagaat aagaaatttg aaagtatgag tgtagtagct
     9901 ggtcttgcag gtgctggatt aatgttaatg atgattcgtc cagagattac gaatgaagga
     9961 gctatattta acttcaacag gtttggagga gaaggaatgc ttgtatcgct agttgcagga
    10021 ttattctctg gattaataat gtctttattt ggttcttttt catttttcgg agaagattca
    10081 gcacttccgg attttgtaag caagtggttt gataatatgt tacctataac agtgataatg
    10141 tttgtaggct ggggattaat ttatggactc aactttgaca tgtttgaaat aatagttaga
    10201 gtatttaaac cagtatcaga tatagcacag acattacctg gatttgtact cttaaacttc
    10261 ttagtagtat ttatatattc tttaggaata agtgggtggg tactatctcc tataacttat
    10321 tcaattcaac ttggtgcaat tgcagctaat gcagcagcag tagcatcagg aggagtagca
    10381 actaatatat atgtttacga agttattcaa acaggctgga taactttagg agggttgggt
    10441 gctacattac cattagttat aatgatgtgt ttatccagag ttggaagaat aaaagcaata
    10501 ggaagagcat gtattgtccc ttctataatg aatataaatg aaccagtaat atttggagct
    10561 ccagtggcat ggaacccatt tttaatgtta cctatgtgga taggaacagt agtaatatca
    10621 ataactactt atttatcaat gagtatggga tttgttacaa ttccaagtaa ggtgtttaat
    10681 ttatggtatg ttccttttgg tatatctact tttatggtaa atcaagatgt tagaggtctt
    10741 attgttttag caataaatat agtattgcta tttatgatat ggtatccatt ttttaaagct
    10801 tatgagaaag aagagataaa attagagagt caagaggttt aaatttagaa attgaaagga
    10861 aattataaat atgacaattg aagaacatat aatagatgaa gaattagtag aagtagcaat
    10921 gcaaataata cttcgtgcag gtgaggctag aacagaaatt aaacatgctc ttaatgattt
    10981 ggaaaagttt gattatagaa atgctgattt aaaactagct aaagcaaaag ggtttatgac
    11041 agaagcacat agagctcaaa ccaagattat acaaggggaa gctggtggag agaaaagagc
    11101 acattcgctg ttatttgcac atgctcaaga tactcttatg accatattca gcgagttaaa
    11161 tataactatg tctttagtag gaatagtaaa gtctatagaa tataaggtaa ataatagtaa
    11221 atgatttaaa taaataaaat aaggagtgat taaattgggt aagtttccta aaggtttttt
    11281 atggggagga gctgtagcag ctaatcaatt agaaggtgca tggaatgaag gtggcaaagg
    11341 ttggtgttta gctgatgtac atatgtatga taaagataga gatatatcta aaccttatga
    11401 gtctgatatg actatagaaa gaataaagtt tgctatgaaa gataataatg gatattatcc
    11461 taagcgtagt ggaatagact tttatcatac atacaaagaa gatttaaagc ttttgaaaga
    11521 gctagggtta aagtgtttta gattttcaat aaattgggct agaatatttc caaatagaga
    11581 tgatttagag cctaatgaag agggattaaa gttttatgat aatcttataa atgaagtaat
    11641 agataatggt atggaaccta ttgtaacact acttcactat gagactcctt tgaatttagt
    11701 attaaaatat aaaggatggt ctaatagaaa agtggtagat ttctttgtta gatatgcaga
    11761 attaatacta aatagatata aaaataaagt taaatattgg atagttataa atcaaataaa
    11821 tttaatacat tatgaatcat ttaattcagt tgcattttgt gtagaccaag ttgataatgt
    11881 agaagagact agatatcaag ctattcatca tcaattcata gctacagctt tgactaagaa
    11941 gcttggaaaa gaaataaatt cagatatgat gataggtatg atgatggcag attgtacatc
    12001 ttatccagaa gattgtgacc ctgaaaatgt agtatttgct ttaaaaagaa ataggctaca
    12061 atattttttc actgatgtaa gttttagggg agagtatcca gtctatatta agagattttt
    12121 caaagaaaat aacataaata tagttatgga ggaaggtgat gataaaatct taaaagaaaa
    12181 tactatggat tttctagctt tatcatacta ttattctaca acagtatcag caagtaaaaa
    12241 caccatgaat ccaactgaca atataaagaa tccatattta aaagcaaatc cttgggggtg
    12301 ggcaattgac ccaaaaggat tatacaatac tttatctcaa tattatgata gataccaaaa
    12361 gccaataatg atagctgaaa atggatttgg aatgcatgat aaatttgaag atggaaaagt
    12421 tcatgatagt tacagaatag attatttagg aaaacatata gaacaaatag gtgaagctat
    12481 agctgatgga accgaaatat tagcttattg tatgtggtcg ccaatagata tagtaagttg
    12541 ttcatctcaa gaaatggaaa aaagatatgg atttatatat gtggatatag ataacaatgg
    12601 aaatggaagt aaagaacgtt ataaaaaaga tagtttttat tggtatcaaa atgtaataag
    12661 aactaatgga gaagaattaa gagaaaagta aatagttttt aaatataaac aacccccctt
    12721 ataaatactg tatatattat taatatagtt ttataagggg ggttataatt gtaaataaaa
    12781 tgatttatta attatatgat tcatagcgaa atttatattt atacttttaa tcataaacat
    12841 atcagtatga ggaatatcta ttgtacttca tccaaatttt ggtagaggta caattctttt
    12901 ttattttaaa atgctataag ataacataat aaactttaag caaaaaatta ttatattata
    12961 aatttacata tatagacatt gactaaatct taattgtata taaaaataag tagttaagag
    13021 gtaatatatt atattactcg ataaatttag acaaataaaa cttatataag gggagataac
    13081 atatgataat tgagctaaac aaaagtaatt ctgaaaatct aacgaagacg gaacttgaaa
    13141 taattaaatt tataaatgaa aatgaatcaa tattaccaga attatctata gtagagattg
    13201 ctcatgaaac atattcatct ccagcaaccg tttcaagagc aattagaaaa tgtggtttaa
    13261 atggattcaa tgaacttagg tatagattaa cagtaaaaga tgaaaatgat gatatacaaa
    13321 atatggggga tataataaat aaatccttta tagaagcaca gagagttata gaacaaatat
    13381 ctttaactac actaatcaat ataataaaaa ctataaataa atctagtaag atatatattt
    13441 tagcaagagg gcttactgaa tatgtagcaa aagagtttag tcttaaattg caattacttg
    13501 attttaatgt tgtttttata aatgacccca acataatgaa aataaaatct aaatcaataa
    13561 aaaaagacga acttataatt atattttcat tgaatggaaa taccatagag cttgtagaat
    13621 cagcacagaa tgccaattta gttggagcta aggttataac ttgctgttgt agtgaaagtg
    13681 caaaacttat aaagtattcg gatttatata ttgtaggata caaacatgaa catatatcaa
    13741 tttctgaata tgaagtatct tccagattgc ccttgtatat tatatctagg ataattatag
    13801 attatatggt cagatataat aattctgaaa attaaattga aaagtctatg aaaatcgatt
    13861 ttctatttgt gaaaagattt tcatagactt ttttattata atgaaaacat acacagcaca
    13921 agcaaggggg aagacaatga tatatacatt aactacaaat cctgcaatag atatgaatat
    13981 atctactaat gggataaaga gaaaattagt aaatcgtaca tcaaatgctg tatattctcc
    14041 taatggaaag ggattaaatg taacttttgt actaggtcat tatggtatag aatctaagat
    14101 attaggattt tttggaggat tttcaggaaa atatatagtt gaagaaagcg aaaagagagg
    14161 atttgacgta ttgcctactt gggtagaaga tacaactcgt ataaatatat ttttaaatga
    14221 tggaagtgat gaatttaaat ttgtaaactc tgggtcatat gtaaatgaaa aacaaaaact
    14281 agatatgcta gataagatac agtcattagc agatataagt tacttatcaa taagtggaag
    14341 tctacctcct ggtattgatg ataattacta tgaggatata tttaaaattt gtaaaaataa
    14401 aagtataaag acaatactcg atataagttc accaaaatta aaggagttac tacagtataa
    14461 tccatatttg ataaaaccaa atgatgaaga aatcaaagat atatttggaa ttattgtaag
    14521 agatgaagaa gatattaagg atgtacttaa attactacat ttaaaaggtg ctcaaaatat
    14581 attgctaact ttaggagaaa aaggttctta tttttataat ggaaaatcaa tttattatgc
    14641 tagtgctcaa ccagttacag tagtcagctc tgcatgtgct ggtgattctg cattagctgc
    14701 ttttttaagt atatggttgg aaaatccaga acatattgaa gaagcattaa aaaggtcagc
    14761 agcaacagga gcaagtgtgg ctgaaagtaa tggtataggt aatttggaga atgtggaaga
    14821 ttatataaaa aatataagag tcagaaaggt ggtataaaaa tgggaaagaa aatgattcta
    14881 ggggtaacag gttgtccaac tggaatagct catactttta tggcagaaga agcattaaaa
    14941 aattcagcca gggaattagg gtgtgacata aaagttgaaa cgaatggagc tataggtgta
    15001 gaaaataagt taacagcaaa agatatcgaa atggcagatg caataatagt tgcttgtgat
    15061 aaaaatgttg atatggacag attcaatgga aagccagtaa tagaagtacc tgtcaaagaa
    15121 ggtatacata aagctaatga acttatacaa agatgtattg atggaaaagt agctattaga
    15181 aaaggaaact tatcaagcag taaaattgca gaagaaggaa atttatcgtt tggtcaaaag
    15241 ttgtataaag acttaatgaa tggtgtatct cacatgttac ctttagtagt agcaggtgga
    15301 gtacttactg ctatatcatt tttatggggg atttattcat ttgacccaaa ttcagaacaa
    15361 tataatcaaa tagcagctac attaaaatct gttggtggat attctatgaa cttgatggtt
    15421 cctgtattgg cagcatttat agctcaatct atatcgggaa gagctggtat gttagcagga
    15481 cttgttggag gaatgatatc atttgataca ggttcggggt ttttaggtgg aatcatatca
    15541 ggatttttag caggttactt agttaaacta tttgtacatt tgttaagaaa attaccacga
    15601 caattagaag gtcttaaatc gatttttata attcctattg tcagcgtagg tcttgtgggt
    15661 gtagcaatgt tgttacttgg tgggccatgt tcagcactta acaatgctat gatgaacttt
    15721 ctatcggggt tacaaaattc aagccctata attttgggaa tagtaatagg atgtatgtca
    15781 gcatttgata tgggaggtcc agtaaataaa gcagcatatg taactggaac tatgcttcta
    15841 ggacagggaa attatttatt tatggcaggt gtatctgcag cttgtataac accaccattg
    15901 gtaatagcaa tagcatctac tttatttaaa aatagattta cagaagaaga tagagcagca
    15961 ggattaatca attatatact aggtagtact catataacag agggggcaat accttttgca
    16021 gcaaaaaatc cattaaaagt gttgccagta cttatgattg catcatcaat atcatcaatt
    16081 ttaacttata taatgaaaat agaagtacca gctccacatg gagggttttt ggttctagga
    16141 ttagtcaata agccactttt atgggtaggg tgtatatttg taggttcatt agtaggtgct
    16201 gtactttata tgatggttac acctaaagta gtaaatgaga aaaatactat agaaaataca
    16261 aatgtaacaa aagatgaaca taaaaatgaa agtgcagaat cggaaaacgt atctaataat
    16321 atctctttat atagcgaaga aacagtaatt ttagatgtta agggaaaaaa taaaacagat
    16381 gtaattgatg aaatgattgg aatacttgat aaatctagtg ttcttttaga taaaaagaag
    16441 tttaaagaag aaatccttaa aagagaagaa atatcatcta caggttttgg tatggggata
    16501 gcgataccac atgcaaaaac agatgcagta aaggtaccac gtgtagcagt aggtgtatca
    16561 aaagaagggt ttgactttga atcagaagat ggaagcttag cacatattat atttatgata
    16621 gcagctacag ataatggtga taatttacac ttaaaaacat tatctcaact atcttcaaaa
    16681 ttaatgaatg aagaattttt aaatgagtta ttaaatagca aaacaagtag agaaatagta
    16741 gcaaaattaa ataacgaaga aatcaaatca gtataaacat ataggaggag aaattatggc
    16801 attagtgaca actaaacaaa tattattaga tgcacaagaa ggacattatg cagtaggtgc
    16861 atttaatgtt gaaaatatgg agatggttat ggcagtaata gaggctgctg aagaacttaa
    16921 atcaccagta atattgcaaa caacaccttc aacaataaag tatgcagggc tagattatta
    16981 tttagcgaat gtaaaggtag catcagagaa ggcaagtgtt ccagtagcaa tgcacttaga
    17041 ccatggttca agctttggac tagctatgca ggcacttaga gttggatata cttctattat
    17101 gattgatggt tctcatgaaa gttacgaaga taatatttca atatctaaat ctgttgtaga
    17161 tgcatgtatg ccttcagata tacctgttga agctgaatta ggtaaagttg gaggtaagga
    17221 agacgattta gatggtggtg atgggggagc atatacagac ccattagaag caaaagagtt
    17281 tgtagagaga acaggggtat catctttggc agtagcaata ggtacggcac atggattata
    17341 taagggagag ccaaagcttg atttagatag attatctgaa attagagatg ttgtatcagt
    17401 tccattagta ttacatggtg ggtctggaat accagatgaa gttattaagg aatctataaa
    17461 aagagggatt tgcaaggtta attatgcaac tgaattaagg attgcttata gcaatggggt
    17521 taaggatgtg cttaattctg acccagaggt aattgaccct aagaaatatg gtaaaaaagg
    17581 tttagagtca gttaaagatt ttgttaagag taggatggaa gtttgtggat gtgtaggaaa
    17641 agcaatagag atagtgaagt gttaataata aagggagaga ataagtaaga ttaaattaag
    17701 gggtgtctca aaatgaactt tttagttcag gaggcactct tttttgtatg aaattaaata
    17761 tattttcatc attccgaaaa taaaaaagaa gattatatct attttgagac agcatcttat
    17821 tttatttttt gattgagatt gtaattgaga aatttgaaat aaggaagatg atataattaa
    17881 ataaaaaatt tctttctaag tttaaattaa tattaaaaag ttataatatg gtaagagtta
    17941 tccaggtaga tgacttctat gctggatata tgataaaata attttgtatg ggatgtataa
    18001 taatcataaa ataagagtat tgcattagtt ttttaactaa aacatgtaaa taggaaaaat
    18061 aatttaataa ctgtgtagta aaattttgaa tttaatataa gacactaatt attaaggcgt
    18121 acgactaaaa tatatattta aattatttta tgaacactgg agggaaagtc atatatgatt
    18181 acaggagaat taaggagcaa agtagacaag atttgggaga cattttggac tggtggatta
    18241 actaatccat tagaagttat agaacaattt acatatcttt tatttattaa aggattggat
    18301 gaagtagaaa caaaaaatga agcagaagca actcttttgg gagtttcttt tgaaaggata
    18361 tttgatgatg aacatcaaca tttaagatgg agtaagtttt ctaatgaagg aaattcagaa
    18421 aaaatgtatg aaatagtaca aaatgaagtg tttcctttca taaaaaaatt acatggaaat
    18481 aaagactcag cttatgcaaa gtacatggga gatgcaatat ttaaaattcc tacgcctctt
    18541 atgttatcta aaatagttga tggtattagt aatttagaat taagtaagga tagagataca
    18601 aagggagatt tgtatgagta tttattatcc aaagtggcta cagcaggtac taatggtcaa
    18661 tttaggactc caagacacat aatagatatg atagtaagac ttattaaacc aacaccagaa
    18721 gatattatag tagacccggc agcaggttca gcaggttttt tagtatcatc acaacaatac
    18781 ttaagggata atcattcaag tcttttctta gtgcaagggc tgaaggagca ttttaataat
    18841 ggtatgttct atggatttga tatggataga actatgctta gaataggtgc tatgaatatg
    18901 atgttgcatg gcgttgacaa tcctaatata gagtataagg attctttatc ggaggttaat
    18961 acagataaag ataagtttac attggtgtta gcaaatcctc cttttaaggg aagtttagat
    19021 tatgaagcag tgtcagcaga tttattaaaa gtgactaaga caaagaaaac agagttatta
    19081 ttcttggcac tttttttaag agttttaaaa attggtggaa gatgcgcatg tatagtgcca
    19141 gatggagtat tgtttggttc aacaggtgga cataaatcga taagaaaaga aatagttgat
    19201 aatcataaat tggaagctat aatatcaatg ccaagtggag tgtttaagcc ttatgcagga
    19261 gtatctacag ctataatgat atttactaaa acagggacag gtggaactga taaggtatgg
    19321 ttctatgata tgaaagctga tggttattct ttggatgata agagaaatga gataaaggat
    19381 agtgatatag aggatattat taagagattt gataatcttg atggggaagt agatagaaaa
    19441 agaacagaac aaagcttttt tgttgatgtg gaagagataa gagagaatgg gtatgattta
    19501 tctattaata agtataaaga ggtagtgtat gaggaagtag tttatgatgc tcctagtgtg
    19561 attataggta gagttaggga gttagagaag gaaatagctg ttggattaga agaattagaa
    19621 agaatgttag aggtataggg tatggagtat ataaaattaa atgaattgtg ctatataaat
    19681 attggcaaaa caccatctag aaatacttct gattattggg gaagtggtaa tagatggtta
    19741 tcaatttctg atttgaaaga aaaatatata tcaaaatcaa aagaagagat aacagattta
    19801 gctgttgaaa aagctaatat gaaattagta cctaaaaata ccgttgtaat gagttttaag
    19861 ttgtctatag gtagagttgc catattaaaa gaagacatgt ttacaaatga agcaattgct
    19921 aactttcaaa taaaaaataa tgaacttata acatctgaat atttatatta tgctttgaga
    19981 actttaaatt ttaataatac tgatagagca gttatgggtg caactttaaa taaaagcaag
    20041 ttaaatgata taaaaatacc atatttcaca atttgtatac aaaataaaat ggtagaagtt
    20101 ttaaataaag ctcaagagtt aataaataaa agaaaagagc aaatagaagc attggatgaa
    20161 ttagttaaat caagatttat tgagatgttt ggggagccaa ttaataatac aaaaaaattt
    20221 gatatgaaga agattaaaga gatttctata tatttaaaaa gaggtgtatc tcctaaatat
    20281 gtagagcaat caaatataaa agttataaat caaaaatgta tatactggag aaatttgaag
    20341 gtagaaaatt gtaaatatta tgatgaaaac ttaaaagaga agatagaaga tatatttttg
    20401 aaacaaaatg atatattaat aaattctact ggaactggga cattaggaag atgtgtaaaa
    20461 tttaacaaaa ttgataattc tgaatatata gcagatagtc atgttacagt tttaagaagt
    20521 atttcaaata acttaaattc agattatttt gcagcgttat ttgaatttac aaatatacaa
    20581 gacacaatat atagaaaatg tgttaatggt tcaacgaatc aaattgagtt atcagttagt
    20641 aagttaggtg aatatttaat aatggttcct ccaattgaat ttcaaaatca gttttctgag
    20701 tttgttaagc aagtggataa attaaaatta aaaatagaaa ccaacttaaa agagttagaa
    20761 gataacttta attcattaat gcaaaaagct ttcaaaggag aattatttaa ctaaacaata
    20821 ttacctaata aacaagaggt gattaaatga gaaatatacc aaatgagatt aaaaactcaa
    20881 taataaatgt atttccaaaa gaaaatactc tagcaatcat aatatttggt agttatggaa
    20941 cagataaaca tacatcagaa agtgatatag acatagcttg gattcccatc aaaaaagtac
    21001 caattacaga acttgcaact aagacagaag ctctaagaaa tatattagac attgatgtag
    21061 acctaaaaat tgttacagat aattatacaa tagcacttaa aaaagctatt ttagaaggtg
    21121 aagttattta tgaatctaaa gattttaagg attatataaa taaattctat tttgaaaaca
    21181 gtgatgtaat agatatctta gattggaggg acatgtatgg taattagaaa caaattatct
    21241 tggaactcaa tagaagaagt aaatagggat tttggttctt gcttgtatga cctgcaaaac
    21301 ttcaaaatct tatatgataa ggaagaaatg cctgagttat gggctagata cataaaagaa
    21361 ggctttaaaa gctatatggt atcatttcta gaattaacaa aagcaatgtt gtattataaa
    21421 tcaattgatt taaacataaa atctaaaaac ttttatgact accttttagc ttgtgagtat
    21481 cacaatttat tacctaaaaa ttcttctata gttatagaaa cacttagaaa attgagaaat
    21541 gatgattctc atggatatga tataccacag tttgaagata tgtacgaatt gtttacagaa
    21601 aatgaagaag tatttgttag tataagaaac agctgtaaga aatagttttt agagagattt
    21661 attttaacta agggacaaaa gggggataaa agccttgggt aattttgatt ttttacaaaa
    21721 gaagaaaaat ttcaatagtt ttaatactgc ttgcttagaa gcagaaaaaa gtatactagt
    21781 tagtccatct acttgtgcaa ctataacaag aagagcttta gagcttgcag taaaatggct
    21841 atatgctaat gatagtgatt tagtattgcc ttatcaagat aatctcagta cgttgattca
    21901 taataatagt tttatagaac ttatagacta tgatatgtta cctttattaa aatatatagt
    21961 taagttaggt aatttatctg tacatactag tgcgaacata gagagaggag aagcaatact
    22021 ttcacttaac aatttgcatc aatttgttag ttggatagac tattgttatt cagatgaata
    22081 tacagcagaa gactttaatg aagatttatt acttcatgga gaagagaaaa ggacgagacc
    22141 agacgaactt aaaaatcttt acgagagatt aagttcaaaa gataaaaagc ttgaagaagt
    22201 aataaaagaa aatgaggaat taagaaagtc actaactgaa aagagaaaag ttaatactgt
    22261 aaactatgat ttcaagatag acgaagtaag cgaatttgag acaagaaaaa gatatataaa
    22321 tatagaatta aagcttgcag gttgggaatt tggaaaagat ataggggagg aaatagaagt
    22381 acaaggtatg cctaatgaaa gtggtgtagg atatgtagat tatgttcttt atggtgaaaa
    22441 tggtaagcca ttagcagtag ttgaggcgaa aagaacgagc aaagacccaa aaattggtca
    22501 acaacaagct aaattatatg cagattgttt ggaaaagaga tatagtcaaa gaccagtaat
    22561 atttttgact aatggttttg atatgtatat ttgggatgac tattcagata gaaaagttta
    22621 tggattttat aaaaaatcag aattacaact tatgatggat agaagaaaga gtaagaagtc
    22681 tttaagttct gtaacaataa atgatgaaat atccaataga tattatcaaa aagaagctat
    22741 tcgggctgta tgtgaggccc ttgaaaataa gcaacgcaaa actcttttgg tatgtgctac
    22801 tggtacagga aaaacaagaa ttgctatatc tatagttgat gtactttcaa gacataattg
    22861 gattaaaaat atattatttc tagcagatag aaaagcattg gtaaagcaag ctaaaaaaag
    22921 ttttactaag ctattaccta acttggcgtt atgtaattta ttggatagca aagacagccc
    22981 agaagatgct aggatgatat tttctacata tccaacaatg atgaatgcaa ttgatgatac
    23041 gaagtctaag gatggaaaga gattgtttac acctggtcat tttgatttaa ttataataga
    23101 tgaatcgcat agaagtattt ataaaaagta taagtcaatc tttgattatt ttgattctta
    23161 cttaatgggt cttactgcta caccaaagga tgagatagat aaaaatactt attcagtttt
    23221 tgacatggaa aatggagtac ctacatatgc ttatgagtat aataaggcag tcgaggatgg
    23281 atatttagta gattatacta gtattgagtt taagactaag attatggaag atggaattaa
    23341 gtatgatgag ctttctgatg aagagaagga agaatatgaa aatacattta atgatgatga
    23401 gagtattgga gacgaaatag ggaataatgc agtaaatgag tggctattta attctgacac
    23461 aatagattta gttttaaata agctaatgac agaggggttg aaaatagaag gagaagaaaa
    23521 gattggtaag actataattt ttgcaaagaa tacaaagcat gctagggcaa tagttgaaag
    23581 atttaataag ctgtatccaa agtatggtgg gaactttgta aaagcagttg actatagtat
    23641 aaattatgta gattctataa tagatgattt ttctgataag aataaattac ctcaaatagc
    23701 agtttcagta gacatgcttg atacaggaat tgacatacct gaaatactaa atcttgtttt
    23761 tttcaagaaa gtgagaagta agactaagtt ttggcaaatg ataggtagag gaactagatt
    23821 atgtccagat ttattaggtg ttgatatgga taaggagaga ttcttaatat ttgatttttg
    23881 taataatttt gaatttttta aatttaatcc taaaggattt gagggaaata aagcagaaac
    23941 acttactgaa aaattattta atataaaggt aagtatggtt aaagaacttc aagatattaa
    24001 atatatagaa ggtgagtatg cagaacttag aaaagaattg ttagaagaac ttataacttc
    24061 tgtaaaagct ttaaatgagg atagttatat agttaggatg aatttaagtt atgtacataa
    24121 gtataaaaat gaaaatgttt ggagcaatat tggagcagta gcacaaaatg agataagaga
    24181 atatatatca ccactcataa cttcatatag tgatgatgaa ttggctaaaa gatttgatgt
    24241 agttatgtat aatatacaac ttgcatactt acaaaataat aatgcaagta aaggtataag
    24301 gcatgtaatg gctacagcag aaaaactttc aaaacttggg actataccac agattcagca
    24361 acaaaaatat actattgaaa aagcaatgac agagaatttt tgggaagatt cagatatatt
    24421 tgaggtagaa gaagtacgta tatcattaag agagcttatt aagtatcttg aaaagtctag
    24481 tcaaaagata tattatacaa gttttgaaga tatgattgta gcagaagata gaaatgattc
    24541 tgtatataat gcaaacaatc ttaagaatta taaaaagaag gtagagtatt atttaaatag
    24601 ccataaagat gaattagcaa tatttaaatt aagaaataat aaaaagataa caaagcaaga
    24661 tgttgaaacg ttggaggaaa tactcttaaa acagttaggt aattgtgatg attataagaa
    24721 ggagtttgga gatactccag taagtcaatt agtgagaaga ctagtgggat tggatagaga
    24781 agctgcaaat gaagcttttt cagagttttt aaataataag agctttaata ctaagcaaat
    24841 acattttgtt aaacttatag tcgattatgt agtcaagaat ggatttatag aggataacaa
    24901 agtgttgatg gaagacccat ttagaactgt tggaagtata attgatttat ttgaaaatca
    24961 tattgaagag agaaataaat tgattaaaac tataaataaa attaaagaaa atgcatcaga
    25021 gataggctaa tgatgttatt tagtgcaaaa ttattgttaa tgatgtagag aataaattta
    25081 ttagtaggta gtctaatatt gggttgaaat agataactag atatggataa tgtaaatata
    25141 caaagagagg tattgaataa ttatgcaata tctcttttta attgataaat aactatgaat
    25201 tactcatgaa gaagattaaa taataatttt taaaattaag tatttgtata ttttatagaa
    25261 taatcatgta tttactttaa taaaataaaa acaggtataa aaaggtatat aataaggctt
    25321 tcatatacat ttatgagtca aaattttgat ataatatata gatacatgga gttatgaatg
    25381 gaatttattt aacttatagg gggagttaat atgaaagcag gagaaattga atttcttagt
    25441 tatttagagg ggtcaaacaa aagttttgta gtacctgtat atcaaagaaa ttataactgg
    25501 aagaaagaac aatgtaaaag attgtttgat gatttagagg atataataga ttctggattt
    25561 agaactcatt tcttagggtc agttgtatct atatatagta tgggaaaaga atatttaata
    25621 atagatggac aacaaagagt gactactgtg tcaatattat tgattgccat gtgtcaaata
    25681 ataaaagagt ttggggaatc aaaaggaatt attacaacag aagaacagat taaggagtgt
    25741 tatcttataa acaagcactc aagagataaa gatggaaaaa taaagttaaa accaatagca
    25801 gaagatagaa aagcgtacta tgaactattt gaagaagaaa tgaatacaga tagaaattct
    25861 aatatagttt caaattattt atatttttat aatagaataa aagaagataa tatatcaata
    25921 gatgatttgt ttgatgctat acagaaatta actatagtag aaatagagtt aaaaaatggt
    25981 gaagatgacc ctcaattaat ctttgaaagt ctaaattcaa ctggcttaga tttaagtgaa
    26041 gctgatagag taagaaactt tgtgttaatg ggtagaagct ctaagttaca agaggaattt
    26101 tataataatt attggtataa aattgaaaaa aatacaagta gcaacgtaag tagttttata
    26161 agagactatt tgactataaa ggagagaagt ataccgaata aaaataaagt atattttagt
    26221 tttaaaaggt atgtatcaga taatggtata gatatagaaa ttttattaaa agatttactt
    26281 aaattttcta actattatag agagatatct tattcatgta ctgatgataa tgatgtaaac
    26341 aaagttttga aaaggataaa caaacttgaa atatttgtat catatccgtt tatattagaa
    26401 ttatttgatg attataatga aggtataata aataaaaaag tacttgtaga atcccttaat
    26461 ttagtagaat gttttatatt aagaagaata gtatgtgatg tacctccgaa tgcactgaat
    26521 aaagtattta tgaacttagg aagggaaatt aaaaaattta gtgattataa agaaaactat
    26581 tctaatatat taagatatat ttttataaat aagaaatcat ctcaaagatt tcctactgac
    26641 agtgaatttt caaatgcttt tgaaactaaa gatatatata atactaagtc aaagaataag
    26701 ttatatatac ttgagaggtt agagaattat agtaataaag aaattgttga tttagaaaat
    26761 ttaatcaata ataatatgct aaatatagag catataatgc cacagacatt aacaaataaa
    26821 tggaaggaat cactaggaga taactataag gagatacatg ataaatattt acatacaatt
    26881 ggaaatttaa ctttgacagg atataattca aaactaagta ataaaacatt tgaagaaaag
    26941 aaagaaatgg aagatggatt taaagatagt aggctttatc taaataaata tatttcatct
    27001 atagataaat ggaatgaaga agaaataaaa aatagaacta agatattact agatagagct
    27061 gtagaaattt ggaaatatcc aagtgttaca tatgaacctc caagtaacag tgaaaatata
    27121 tttacgttag aggatgatga tgttaatttt acaaatgaaa gtatagtatc atttagtata
    27181 ttaggagagt catataaggc taaaaattgg acagaatttt atgaacaagt tgctcttact
    27241 ttatatgatt tggattctgt aaggtttaac agtattgtag acaaaactta taaaagagat
    27301 tttatagata atattaagtc tagagatgca tataaattaa gaaaaggtat taaaatatca
    27361 gaaaatatat atttagaaac aaatttaaat acagaggcta aattaaatat aattagattt
    27421 ttacttaatg agtttgatat agagttaaat gaagtaatat tttccataaa ataatgaaat
    27481 atatgcattt tttgcgtaat agaatattaa ttatattaaa aataaaatag cacctcttga
    27541 tatagattta tagctcaaat ttatatcaag aggttacgtt
//
LOCUS       DAYAOO010000052        25890 bp    DNA     linear   BCT 12-OCT-2024
DEFINITION  TPA_asm: Clostridioides difficile isolate ST8-SSI-h139-18
            SAMN40601845-rid21577343.denovo.052, whole genome shotgun sequence.
ACCESSION   DAYAOO010000052 DAYAOO010000000
VERSION     DAYAOO010000052.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN40601845
            Sequence Read Archive: SRR28438827
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 25890)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 25890)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-MAY-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-MAY-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002157583.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002157583.1
            Genome Coverage       :: 163x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/11/2024 16:19:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 4,038
            CDSs (total)                      :: 3,963
            Genes (coding)                    :: 3,930
            CDSs (with protein)               :: 3,930
            Genes (RNA)                       :: 75
            rRNAs                             :: 6, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 60
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 33
            CDSs (without protein)            :: 33
            Pseudo Genes (ambiguous residues) :: 0 of 33
            Pseudo Genes (frameshifted)       :: 7 of 33
            Pseudo Genes (incomplete)         :: 25 of 33
            Pseudo Genes (internal stop)      :: 11 of 33
            Pseudo Genes (multiple problems)  :: 8 of 33
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..25890
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN40601845-rid21577343.denovo.052"
                     /isolate="ST8-SSI-h139-18"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Denmark"
                     /collection_date="2018"
                     /collected_by="Statens Serum Institute"
     gene            complement(121..1650)
                     /locus_tag="ACGI5H_002426"
     CDS             complement(121..1650)
                     /locus_tag="ACGI5H_002426"
                     /inference="COORDINATES: protein motif:HMM:NF012862.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="caspase domain-containing protein"
                     /protein_id="HFG9698127.1"
                     /translation="MKSLKALIVGVSKYSIVKNKDLLFCKNDIIEINNVLHKRLGITS
                     NNIRTLGMEYEVRKDLFFKTFQEISDSIGDDDTFIFYFSGHGCICNNGVHYLVLSDEL
                     VSIQFVIDFIEGLNCKNKIVFIDCCFAGKFNVSDKQKINIKDIFSLFDRKGCAVLVSS
                     SEYQESFSLPDSSISRFTSLLSEALRNEYIVRKGELSLRAISKYINLRMSILNKNYIN
                     CKQNPIFRSNILGDIYFNVKDYKSYIKKKVFQEHDDYIIYNVKSLHISIIKRYSVEVI
                     LKNKFSYCDISEISKEVFDIVKSVEVYNSEIGEDRLKGKDANIIWVYFGKDEIDMING
                     IYMCKTTWIDKYQEKDIWYSVNGKNKFFINGVHTETYDNYESLKSYISQNTITKEKAV
                     YEVKEILTNMINISEEIISFYNEYENKKICEDNIFQIIDSRKKKMDECYNKVINLDFP
                     PIEIKDWFDKCINLVSTIQNFGVYWDHSRTEENRKQCMEMNIEDYYKDLREVIRLSEE
                     I"
     gene            complement(2349..3779)
                     /gene="dcm"
                     /locus_tag="ACGI5H_002427"
     CDS             complement(2349..3779)
                     /gene="dcm"
                     /locus_tag="ACGI5H_002427"
                     /EC_number="2.1.1.37"
                     /inference="COORDINATES: protein motif:HMM:NF012372.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003886 - DNA
                     (cytosine-5-)-methyltransferase activity [Evidence IEA];
                     GO_process: GO:0006304 - DNA modification [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA (cytosine-5-)-methyltransferase"
                     /protein_id="HFG9698128.1"
                     /translation="MKKITIDKNRVRKIMKEKNIRSQNQLALNMGITKNQLSAILSEK
                     FTPIKSNVEKLCEVLDIGFDEIMCLEDVNEKQLKFTNICSSNKDYIEHRDCTYKELSE
                     YELNPRERNKNNKHIDISNVLAKRAYTCVELFAGAGGLALGLEKAGFKEVGLVEWDKY
                     ACDTLKLNRPDWNVIQGDIVKIAENGIKNYIDNNIEIDLLSGGYPCQAFSYAGKKLGL
                     EDVRGTLFYSYAKILEELKPKVFLAENVRGLVSHDGGKTLKTMIDVFSEIGYNVKYEI
                     LKAVNYGVAQKRERVIIIGTRKDLSHVDFKFPKSFEYVATLRDALKNVPKSEGARYPE
                     RKKKVLDMVPPGGCWIDLPDEVARDYMGKSYYSGGGKRGMARRISWDEPCLTLTCSPA
                     QKQTERCHPDETRPFTTREYARIQSFPDEWEFTGSVSQVYKQIGNAVPVKLGKAIGLS
                     IVDYLNKIEKIYVTEEVAITEEEYVI"
     gene            3992..4708
                     /locus_tag="ACGI5H_002428"
     CDS             3992..4708
                     /locus_tag="ACGI5H_002428"
                     /inference="COORDINATES: protein motif:HMM:NF025864.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PmeII family type II restriction endonuclease"
                     /protein_id="HFG9698129.1"
                     /translation="MTELEKQEILDKAKDFFTNILVANHKKNTIKLNLKAFNINPFLV
                     KYLASFLTGSNKPEDIAKALIYPRVLGTSINTSFGTNLQKFCITTLDGFASTTSGIDI
                     EFIDCIDGRRKFCQIKAGPNTINKDDVKTIIDHFSSVKRLARTNGLSLSYNDLIVGVF
                     YGTENELNAHYKRINEEYPVVVGQDFWYRLTGDENFYFDLIDTIAQSALEEDCTVLLK
                     KTISNLADEISKDKSLFNQK"
     gene            complement(4953..5231)
                     /locus_tag="ACGI5H_002429"
     CDS             complement(4953..5231)
                     /locus_tag="ACGI5H_002429"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891535.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF6809 family protein"
                     /protein_id="HFG9698130.1"
                     /translation="MYDEIIEIYFDYWINEHMYRKVLEKDEYYNDRCKEIKKVNKLLE
                     KNLSEEKKMDVLIELNDLFNSVIEIERELGYKLGFKAGARFMIELLNS"
     gene            complement(5479..6813)
                     /locus_tag="ACGI5H_002430"
     CDS             complement(5479..6813)
                     /locus_tag="ACGI5H_002430"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429599.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replicative DNA helicase"
                     /protein_id="HFG9698131.1"
                     /translation="MDNMSNLVKNTEAEQSILGSILLDSRKIEEIEILISEDMFYHQE
                     HKHIFNSVKDIHKRDEPIDIITLTEDLKKKGLIDYVGGISYLTKLSTIVPTIGNVSHY
                     IEIVIEKYKNRNIIDKFNKFKLGEIDDNTLIYQLEKYVNEVNQKLVKKDSSITAISER
                     AFEYINDEIEEGIDIGIKFLDETIGGLYSGELITIAAKSGRGKTALALQIMRNVVFQG
                     KKVLFISGEMSDIQILFRNIASLTGISVVKMKNRNLNEEEIIKYINALSTLNQENNLY
                     INDSVNTISGIKREIKSIKPDVVIIDYLQILDYEGKEVGEAKFADLSRQIKKITLDFN
                     IPIIQLAQLNDELKDERPKGDRVMRSSKQIYMDSNSVIYIHRPTEKEALDYCKTMGIE
                     DIKELRRREKGFGANLSEIIVAKNRDGESGFRPYWYIGSLFSFKECKKVKEV"
     gene            complement(6826..7569)
                     /locus_tag="ACGI5H_002431"
     CDS             complement(6826..7569)
                     /locus_tag="ACGI5H_002431"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729175.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9698132.1"
                     /translation="MSNLGWIKLHRKIKESPLYKDCNSKQRDILINLLLSVNHKPNKW
                     VYGGKEYEVKSGQLITSLESIANMCSKDVSIQNVRTALKKFERYGFLTNKSTNKNRLI
                     TIENWELYQSNEENQQTNQHAINKQLTTNKNVNNEKSKIYSEIIEKFNITCTELSKVK
                     KLTEARKKVINARIKEYDKETVLEIIHIVSKTSFLNGSNEKGWKANFDWIMSPNNFIK
                     ILEGNYQDKSINVKVDAEAYSPDDSQLKW"
     gene            complement(7590..7904)
                     /locus_tag="ACGI5H_002432"
     CDS             complement(7590..7904)
                     /locus_tag="ACGI5H_002432"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433761.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9698133.1"
                     /translation="MADTNNLEVLKTLQATLNILVKQEQEAQEKEKGYKEIQTYRRDK
                     AQLITCKEASKIYPIGESKFRQLCHSKNKGFPCIWIDNRVYIIKNKLDNWFIENANGI
                     KL"
     gene            complement(7908..8102)
                     /locus_tag="ACGI5H_002433"
     CDS             complement(7908..8102)
                     /locus_tag="ACGI5H_002433"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891540.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HFG9698134.1"
                     /translation="MKLKLKRIEKGIKQYELAEKVGISRYYLSSLERGKSKNPSNMLM
                     LKLAQELDTSVEELFFDKEE"
     gene            8242..9102
                     /locus_tag="ACGI5H_002434"
     CDS             8242..9102
                     /locus_tag="ACGI5H_002434"
                     /inference="COORDINATES: protein motif:HMM:NF024252.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HFG9698135.1"
                     /translation="MIDNTIGKKIKQYRKSINMSRDELANKIGCSVYAVAKYEQGQRK
                     PSLDMIKKISTALSIPINRLIIDESDLDTSTNNYTNLKELDLVVKTFDNYSAKLIGNN
                     ISKFRNINNISLKELSEKINCSENEIINYENGTKMPRIEILKKIALATYTKIEDLFGF
                     PLEEIKIDNQTILYRNPQTGYIIDNFLIDFINKDINIDNTPVSYYIDKSEFDLVIHIL
                     KNYGYDVKTDYKTKFEIADNADTIKPISLSFSDFKDFSKNLNWVINGLVENFIQENSN
                     GLIEDEDEEY"
     gene            9199..9951
                     /locus_tag="ACGI5H_002435"
     CDS             9199..9951
                     /locus_tag="ACGI5H_002435"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898282.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fic family protein"
                     /protein_id="HFG9698136.1"
                     /translation="MNKSYIPKYTHKFPTNLPHGDKKYTLTYIRRMISEFVYDMGNLE
                     NNPFTFPEVQTLLDGITVGGHKLSDQNQILNIKSSWDYVIKLSNKENLSLNKDTICSI
                     HKIVAKDEALIVGDFRNGNIGIAGTTQYECIEATLLNDLFVSDINIINKITNPLEKAI
                     IINLWLSYCQFFYDGNKRTARLTSNLILISNDIGVLSIPAKHKQEYNTLMLNFYETLE
                     ADEVIKFLLEKCITFFDEYNYKSYKELFKNGN"
     gene            9941..11107
                     /locus_tag="ACGI5H_002436"
     CDS             9941..11107
                     /locus_tag="ACGI5H_002436"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861856.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HFG9698137.1"
                     /translation="MATKRANGEGSIGKYKDGWRSRIMIGYNEDGKPIRKEFYGKTQK
                     EVKDKLDAYKKQYYLSSDISDDKITLEHWFYNWLFEYRIKDLKPKSFERYESIYRNYI
                     KDTDLGNVKLKDLRVSHIQKYYNRLLDSNKSIPTIRQINTKLKTCLSEAEKQGLIQRN
                     YCTMVNIPVEKKENKLEILTLEQQKSFIKAIDGHKLEVLFLLALGTGLRLGELLGLKW
                     FDIDFKKSNLTVKRTLQRTYFIDKTGNRELKVLEQEPKTSNSYRTVPIPKDVLNKLKE
                     HKVNQNSDILKAGELYRNDNYVFCNELGAPIDDKRPLRNLKSILNSLDIEPIKFHGLR
                     KTYATRLFENDVPPKTVQVLMGHYDISITLNIYTQVMEDKKIEAVEKLDKIFSL"
     gene            complement(11224..11454)
                     /locus_tag="ACGI5H_002437"
     CDS             complement(11224..11454)
                     /locus_tag="ACGI5H_002437"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433747.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9698138.1"
                     /translation="MEANKTLLQSLYKKIILEFSKQTGKSLEESMDYLYTSETYKLIS
                     EGISDMHCKGHIYLAQELMLENGLMYHKGYPR"
     gene            complement(11703..16274)
                     /locus_tag="ACGI5H_002438"
     CDS             complement(11703..16274)
                     /locus_tag="ACGI5H_002438"
                     /inference="COORDINATES: protein motif:HMM:NF024685.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SIR2 family protein"
                     /protein_id="HFG9698139.1"
                     /translation="MTFEEIMEFNKPYNQKNFDELVNAIKDGYVVPYIGAGMSMLFKD
                     IYPSWSTFLNNTSEEYLEDEDKILFEKIEDYEKKAEFLYEELAKVRFSKHLKKVFGAG
                     YLDAKDKDDFIDKCVYLIPIIFGSGLIITTNYDKVLEKNYGLHNKTVLVSHPGHFEAL
                     NNALRNNELVLYKIHGDITEPTTSIVLTKEQYEKAYSNDELRKMLTQVYTSKELLFLG
                     CSLEKDRPLELLQQVSEAGTGHYAIIPVSSEKKKHRRIELENEYYIQTIMYPEGKHEC
                     VRIILERILEIVLPDEYRRLKDRSLKESRLTNLSCRLTEKWFQNQNNIQIKNLGDRYL
                     PELNVELSLENTFNALGKNEEFKQRFDEKTDKVLSSIKKQKINEVEVDVLVIEEIIQQ
                     FYDKANERLDIKLLKKHFEKISAALDDRINNFKNIIINEDCEKSKKREDEIYKLKQTQ
                     KDIYVYIKYLDSKEIKVVNSPYILLHSAGGMGKSHIIAHTIEKRNMDGHKSILFLGQH
                     FKLDKTPIKHMLEILEIECEFEELLEILNEIGEKEQQRVILFIDALNEGQGKELWKYY
                     LNGIVEQIKKYPWIGLILSIRSEYIPSLIDNNNKIKENLVFIEHQGFSSIEHKAMKKY
                     FDYYGIPYSNIPMPNQEFRNPLFLRIMCETFKGEEINLDTISFTDIYKNYLNILNLRI
                     SESCNYSRHANVVTEVLNEMIKYKYGDGLGNNLIPANKSVEIIINIASKYKINNVIID
                     ELIANGIVNKTVNLNDEEYMHVTYEKLEDYLYANLLVKELKEIGVVDFSHKYKYLVEY
                     EDILEVLAIVLSEETGSDIPNEIFEVFKNKETNYNVISAFINALKWRKKSTITEKTLD
                     YINKIVLGKSYYKIDFYNVLILISTKVNHTLNADYIVKYILQNTMADRDAIFIPIFNE
                     VYEEEESSIKRLLGWCFDFEGFDNTSNETIRLSAMMIATFLISSNRDLRDKSTKALVN
                     LLTGKMDIVIDLLKTFEDVDDPYIIERLYAVAFGCVVSEQSEEMIEALAVYVYNKIFD
                     VDYVYPNILLRDYAKNIVDYAKYKIDSSVLKDMNVEPPYKSIFPKVPTDEEIEGYKYD
                     YKASDFKDYYWSQNTILNSMEVEYTRDGQPGWYGDFGRYMFQHYFHKWKGLDYNDLKN
                     IAIKKVFDMGYDVNKHGKFDRTVQNGRLRDSKYERIGKKYQWIALYELAAQAADNYKI
                     EVYTDAYGTKKEIYCKGTFEPDIRNIDPTVMTVINNNNNKRVHNQLFQFSPIPNNEWL
                     GDFSDLPSINDMVNSVYKNQDFLLLNGWYTWKEENDFKNKNYKNPEKDMWVLINSYII
                     KNDQLEPIVNALKGKDFMGRWLTEPNSNYTLYNKEYYWADGYYFFQNSYYCGEEWVQI
                     DEHKNILEKDYKVLLPTYSYTTEREGDIFQEDFSGTWHKPCSTLFYGLKLRYGQGDSI
                     LYNDYGEVVCFESSELLNEEIGFFINKEIFLKYLNEQGYSVFWTMLAEKRVLEEPYMD
                     RKYIQPTISGVYTLNGENRLVGETIESEY"
     gene            complement(16679..18526)
                     /locus_tag="ACGI5H_002439"
     CDS             complement(16679..18526)
                     /locus_tag="ACGI5H_002439"
                     /EC_number="3.1.21.4"
                     /inference="COORDINATES: protein motif:HMM:TIGR00571.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0009036 - type II site-specific
                     deoxyribonuclease activity [Evidence IEA];
                     GO_process: GO:0009307 - DNA restriction-modification
                     system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DpnII family type II restriction endonuclease"
                     /protein_id="HFG9698140.1"
                     /translation="MKPILKWAGGKTQLLDILRKQMPTGCDFSSMTYIEPFVGAGALF
                     LYLLEEDIFNKYVINDINSKLINLYIKVRDDLEELITELTNLKEQYISYEEGSSDREK
                     MYYDIRDRFNILTNEKNIENEDCIKQASYFIFLNKTCFNGLYRENSRGEFNVPFGRYK
                     NPSFFDKNELEKLSMLLNKRDSRGELKVKILNKNYLNLENIIDKNCFVYLDPPYRPVT
                     IGGFNSYNKGNFNDDSQIELSKFYKVLDKIDTKLMLSNSDPKVLDEEDTFFDDLYSDF
                     NIKRVHAKRFINSKGNGRGFITELLITNYEEVGNQMELVKNIHKNKSKDEIFKELLEN
                     LKGTIASWDYYVNWNKALENTRKIEVQLNILNYLIGKEDIENETKNLLKEYPEVLSVI
                     PIVIASRDNEFKILDPSDEDMFKYKLFNFKKRKSISDEESELATEFLKKIKFLDLLKQ
                     KNIKNLVDYVFGVEVGLDTNARKNRTGSSMETLVERYVKNMCEKNNWSYLTQATVKKI
                     SEKWSIEVPTDKSKRKYDFAINNNGKIVLVEVNFYNGGGSKLKSVANEFTKLDKYIKD
                     GGFTFCWITDGLGWLESSIPLRDAFDKMDYIFNLDMVDKGSLEYIIKNL"
     gene            complement(18954..19303)
                     /gene="ssrA"
                     /locus_tag="ACGI5H_002440"
     tmRNA           complement(18954..19303)
                     /gene="ssrA"
                     /locus_tag="ACGI5H_002440"
                     /product="transfer-messenger RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00023"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00023"
     gene            complement(19461..19916)
                     /gene="smpB"
                     /locus_tag="ACGI5H_002441"
     CDS             complement(19461..19916)
                     /gene="smpB"
                     /locus_tag="ACGI5H_002441"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421925.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="SsrA-binding protein SmpB"
                     /protein_id="HFG9698141.1"
                     /translation="MAGKKILATNKRARHEYFIEETYECGIELKGTEVKSIRQGKVNL
                     SDGFASVDNSEVFLKQVHISPYEQGNIFNVDSLRVRKLLLHKHEIRKLIGATTIKGYS
                     LIPLSLYLKNGKVKVEIALAKGKKLYDKRQDMAKKDAQRRIEREMTGKY"
     gene            20501..21328
                     /locus_tag="ACGI5H_002442"
     CDS             20501..21328
                     /locus_tag="ACGI5H_002442"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AIM24 family protein"
                     /protein_id="HFG9698142.1"
                     /translation="MDLSKKVKILENASDGKSEFEILEFEKLEGASSPLMAMGLYFAR
                     EAGLKARQIKIKLNNSSIKTEAGALYYYKGNISSETKIGGVGGLFKKGISGALTNESM
                     MKPVYKGTGEVYLEPSFRHYLFMSLDNDSIIVDKGLFYCCSDTIEVKAFTQKNFSSAL
                     LGGEGFFQIELSGTGVIVLECVVPQSEIVEYELKNGEELKVDGNFAIARTSGVNFSVT
                     KSDKSLIGSALNGEGFLNTFTGNGTVWLAPTQVMYEKLSFGAMPTNDNMNNKVSKQK"
     gene            22353..22817
                     /locus_tag="ACGI5H_002443"
     CDS             22353..22817
                     /locus_tag="ACGI5H_002443"
                     /EC_number="2.3.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861860.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:0016746 - acyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HFG9698143.1"
                     /translation="MNLNKVKFTEEHAIEVTNWKYEGKYSIYNLPPWEEIKKKNFSLA
                     KEDKRKNFISFINDNKELIGFINLLDEGSSVFFGIGMKPNYCGMGIGKEIIGLGLQEC
                     RNKYSTKPIVLNVRTWNMRAVKCYESQGFKIVETKVQKTHLGDGEFFVMRYQ"
     gene            complement(23084..23728)
                     /locus_tag="ACGI5H_002444"
     CDS             complement(23084..23728)
                     /locus_tag="ACGI5H_002444"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903589.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HFG9698144.1"
                     /translation="MFGQSFQNCLVLIKENFKLSTLTNLICSIILLCMVPLIQGVANL
                     DRISTAICLENYVAIIGIVMLVPVFSLEQSKEIDEIVSSKALSQVIVQLIRILMSIIG
                     IVVLIIGFVNVLIYLGCNFPVVEYIIGSFASAMFIGSLGMFFSNLFNNTIIGYMISIG
                     YLILNMMTKGKYVGKFFIMSMSQGSFDEKYWLILGSVVLIIASLLIKPVKRKIR"
     gene            complement(23658..24947)
                     /locus_tag="ACGI5H_002445"
     CDS             complement(23658..24947)
                     /locus_tag="ACGI5H_002445"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429585.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HFG9698145.1"
                     /translation="MNLFIKECKNILKSMVYYIFIVVLVFFYISQLGSSVSNDVSKNI
                     PNDGNPLVAPQKVENIEEYYSVHNQYPYGQKESMKTEKVIPNATINLIREYQKNTYTT
                     YPTGVVKYIKLDQNKTKTIEKYIEEITGKSISEINSLWKTDESIKIDYSKVSLERFEE
                     IMQRVDDILGGGSAYAFDKLQRFGVVPVTYDEAMKNYNYTIQKDKVSNGYARIFCDYI
                     GIVLSIFPVFVAVFMSLKDKRSRMREIIYSKQVSSCKIVLSRYFALVFMMILPVLILG
                     MKDLLPLIFFAKDKGISIDNLAFIKYTLWWILPTLMIVTAVGMSITILTDTPVAIIVQ
                     LIWWLYSINSTGLKGDYSTMGLMIRHNSVLNGDIIIQNFNQIMINRIVISLGALVLVL
                     LAIFLYEQKRRGNLDVWAKFSKLFSSNKRKLQIKHFN"
     gene            complement(24944..25816)
                     /locus_tag="ACGI5H_002446"
     CDS             complement(24944..25816)
                     /locus_tag="ACGI5H_002446"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429584.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HFG9698146.1"
                     /translation="MEMKIAVSNLSKRFGKKQALDNINLEIDSGMFGLLGRNGAGKTT
                     FMRILATLLSKTEGSIHMCGVPIENTKEIRNMVGYLPQDFSMYPNMTVYKAMDYLAVL
                     SDIPLRKRRKIIAKLLSKVNLTNYQNVKVKSLSGGMNRRLGIAQALIHNPRVLIVDEP
                     TAGLDPEERIRFRNLLCEIANDRIVILSTHIVGDIEATCENVAILNSGKVIYNGSTEA
                     LAKLAEGKVYSIEVDKKDIENIKSRFIVIGMLTHGGKAILRIISDDKPFETAVNCNPT
                     IEDGYMLIMGGDNI"
BASE COUNT         8868 a         4134 c         2693 g        10195 t
ORIGIN      
        1 tataattgta tcttctatca tgtttagtgt aaacaactta ttttaattta aattcgtaac
       61 caacaaagta ccaatctgac ttataattct atattagtac aactatggaa aaatttaatt
      121 ctatatctcc tcacttaatc ttatgacttc tcttaaatct ttgtaataat cctctatatt
      181 catttccata cattgctttc tattttcctc agttctacta tgatcccaat aaactccaaa
      241 attttgtata gttgacacta agtttataca tttatcaaac caatctttaa tttcaattgg
      301 tggaaaatct aaatttataa ctttattgta acactcatcc atttttttct ttctactatc
      361 tataatttga aaaatattat cttcacatat tttcttattt tcatattcat tatagaagga
      421 tataatttct tcagatatgt ttatcatatt tgttaaaatt tctttaactt cgtatactgc
      481 cttttcttta gtgattgtat tttgacttat atatgatttt aagctttcgt agttatcata
      541 tgtttcagtg tgaacaccgt tgataaaaaa tttatttttc ccatttacac tataccatat
      601 atctttctct tgatatttat caatccaagt agttttacac atatatattc catttatcat
      661 atcaatttca tctttgccaa aatataccca tattatatta gcatcttttc cttttaatct
      721 atcttctcct atttcactat tataaacttc aacagactta actatgtcaa aaacctcctt
      781 agatatttct gatatatcac aataggagaa tttatttttt aatataactt ctactgaata
      841 tctttttatt atacttatat gtaaagattt gacattgtat attatgtaat cgtcatgctc
      901 ttgaaaaact ttctttttta tataagattt ataatctttt acattaaaat atatatctcc
      961 cagtatgtta gacctaaaga taggattttg tttacagttt atataatttt tgttcaatat
     1021 actcatacgc aaattaatat acttgcttat tgctcttaaa gataactccc cttttcttac
     1081 tatgtattca tttcttaacg cttctgataa taaacttgta aatctactaa ttgaactatc
     1141 tggaagagaa aatgattctt gatattcgct acttgatact aacactgcac atccttttct
     1201 atcaaacaag gaaaatatgt ctttaatatt tattttttgt ttgtcactta cattaaattt
     1261 acctgcaaag caacaatcaa taaatacaat tttattttta caatttaatc cttctataaa
     1321 atcaattaca aattgaatag aaactaattc atcacttaat actaagtaat gcactccgtt
     1381 attacatatg catccatgcc ctgaaaagta aaatataaat gtatcatcat ctcctataga
     1441 atcgcttatt tcttgaaaag ttttaaaaaa taaatctttt ctgacttcat actccatacc
     1501 taaagttctt atattattcg aagtaatccc cagtctttta tgtaacacat tattaatttc
     1561 aattatatca tttttacaaa atagtaaatc tttattttta actatactat atttacttac
     1621 tcctacaatt aatgctttta agcttttcat attccattcc ccctttataa tttttcaatt
     1681 taatatactt aaaatgatgt tttaattgtt ttattgattt tataaaagct agtatcacac
     1741 tacttttttg actttttcat tatttacttt tgtagttgga ttataatttt tcaaggtaag
     1801 tatatatata tttatttaca tcgcacccat ataatttata tctctgattt atctgacctg
     1861 aacttagtgt aatttaaacc aatgtaaaat catctatctc ttcaccatat attttttaaa
     1921 attccccaaa atattgatgt taatagaatt tcatgtgttt tttgtattct actatccata
     1981 agaattttaa agtgagtaaa tatttccaat catttatatc ttatttaata tcattttatt
     2041 ccctcaagta tttatttaaa ttgttatgct ttatttataa aattatacat acatttctaa
     2101 agttagacat acatctttaa aaacctttaa tttgtgctac tttttttcta aaaataataa
     2161 atatataaaa attatatata caaaaaatta agttatgact agtttataaa taagtacata
     2221 ataaaattaa agagagcaat tttttttgct ctctttcaaa atttatatta aattgtaata
     2281 ataaaaataa aaacgctagt tatctaaggc taatattttc aacgattata taaatatcta
     2341 cataacagtt aaattacata ctcttcttca gttattgcaa cttcctcagt gacatatatt
     2401 ttttctattt tattaagata atctactata cttaatccaa tagcctttcc tagcttaaca
     2461 ggaactgcat ttcctatctg cttgtacacc tgactaactg accctgtaaa ctcccactca
     2521 tcaggaaaac tttgaattct agcatactct ctagttgtga atggtctagt ctcatctgga
     2581 tgacaccttt cagtttgctt ttgtgcagga ctacatgtta aagttaggca tggttcatcc
     2641 caacttattc gccttgccat acctcttttt ccgccaccgc tataataact ttttcccata
     2701 taatctcttg ccacctcatc tggcaaatct atccaacacc cacctggtgg taccatatct
     2761 aacacttttt tcttcctctc aggatatcta gctccttccg attttggaac atttttaagt
     2821 gcatctctta acgtagcaac atattcaaac gacttaggga acttaaaatc cacatgtgac
     2881 aaatcttttc ttgttcctat tataataact ctttccctct tttgtgcaac tccatagttc
     2941 acagccttta gtatctcata ttttacattg tatccaatct cgctaaatac atctatcata
     3001 gtctttaatg tttttccacc atcatgagat acaagacctc taacattctc tgctaaaaac
     3061 accttaggct ttaactcttc tagaatttta gcatatgaat aaaacaatgt ccctcttaca
     3121 tcctctaacc ctagcttctt acccgcatag ctaaatgctt ggcatggata accacctgat
     3181 agcaaatcta tctctatatt attatcaata taattcttta ttccattttc cgctatttta
     3241 acaatgtcac cctgtataac attccagtct ggtctattta attttaatgt atcacaagca
     3301 tatttatccc attctactaa tccaacctct ttaaaaccag ctttttcaag gcctaatgct
     3361 aatcctcctg ctcctgcaaa taattcaaca catgtatatg ctcttttagc tagtacatta
     3421 cttatatcta tatgtttatt atttttattt ctctctctag gatttaattc atattcactg
     3481 agttctttat atgtacagtc tctatgctct atataatctt tattactgct acaaatattt
     3541 gtaaatttca gttgcttttc atttacatct tccaaacaca taatttcatc gaatccaata
     3601 tctaacactt cacataattt ttctacatta ctttttatag gtgtaaattt ttctgataat
     3661 attgcagata actgattctt agttatgccc atatttaatg ccagttgatt ctgacttctt
     3721 atatttttct ctttcataat ttttctcact ctatttttat caatagttat ttttttcatt
     3781 tagttcacct cttaataaat aatataccct taaatagtta ataaaataca ttaactattt
     3841 aaggatatat tatcataatt ctaattttta tgtaagtagt tataaaaact taaaataaaa
     3901 tatctgtaaa caacctaata ttacctcata attttacaca ttatggaata tattgtataa
     3961 ttacattaat actttttagg gggattattt tatgactgaa ttagaaaaac aagaaatact
     4021 agataaagcc aaagattttt ttacaaatat tttggttgct aatcataaaa agaatactat
     4081 taagttaaat ttaaaggcat ttaatataaa tcctttttta gttaaatact tagctagttt
     4141 cttaacagga tcaaataaac ctgaagatat tgctaaagca ttgatttatc caagagttct
     4201 aggcacttcg attaatacgt ccttcggaac taatttacaa aaattctgta ttaccacttt
     4261 agatggtttt gcctctacaa cttctggcat tgatatagag tttattgatt gtattgatgg
     4321 tagaaggaaa ttctgtcaaa ttaaagctgg accaaacact attaataaag acgatgttaa
     4381 aactataatt gaccacttta gctcagttaa aagacttgct agaacaaatg gactttcatt
     4441 atcttataat gacttaattg ttggtgtttt ttatggaaca gaaaatgagc ttaatgctca
     4501 ctataaaaga attaatgaag agtatccagt agttgttggt caagattttt ggtataggct
     4561 tactggtgat gaaaattttt attttgattt aatagataca attgctcaat ctgctttaga
     4621 agaggactgt actgttttac ttaaaaaaac aatatccaat ctagctgatg aaatttctaa
     4681 agataaatct ttattcaatc aaaagtaata taaaaatgat taaatagcat aatttacatt
     4741 tttagatatt taaaaataat attcaccaaa caaaattatt aagtaaaatg aaatgtatct
     4801 tataaaagct gagctataag taaatctttg taaaaacaaa tttacttata gcttttttat
     4861 gttcaaaaaa cacaaattat atactattta atatattata aacttttatt tgttaatact
     4921 ctctactaaa tttctaacat ctcttatata aattaactat ttaataattc aatcataaat
     4981 ctagctcctg ccttaaaacc aagcttataa ccaagctctc tttcaatctc tataactgaa
     5041 ttaaataaat catttaactc tatcaataca tccattttct tttcttctga taaatttttt
     5101 tctagtaatt tattaacttt cttaatttct ttacatctat cattataata ctcatctttt
     5161 tctagtactt tcctatacat gtgttcattt atccaataat caaaatatat ttctataatt
     5221 tcatcataca tgttagtacc tccttgactt tcatctggta cttaatatat acttaacttg
     5281 tgtagattag tgtacattaa gtacctaatt tataaaggta gttgttatat ttatatggca
     5341 actacctttt tctaataaat ttttcaatct aaatactata tattttaaat cttcattgct
     5401 tactattgag gattatatac ttttcttcta acactcctta aacaatagtt tatatatcac
     5461 ttaataaatt atattttttc atacctcctt taccttctta cattccttaa aagaaaacaa
     5521 acttcctata taccaataag gtctaaagcc tgattcccca tctctatttt tagcaactat
     5581 aatttcactt aaattagctc caaaaccttt ttctctacgt cttaattctt ttatatcctc
     5641 tattcccatt gtcttacaat aatcaagagc ctctttctct gtaggtctat gaatatatat
     5701 gactgaatta gaatccatat atatctgttt tgaacttctc attactctat ctccttttgg
     5761 cctttcatcc ttcaattcat catttaattg agccaactgt ataattggaa tattaaagtc
     5821 taaagtaatc ttttttattt gccttgataa atcagcaaac ttagcttctc caacttcttt
     5881 accttcgtaa tccaaaatct gaagataatc aattataaca acatctggtt taatactttt
     5941 tatttctctc ttaattcctg atattgtatt gactgaatca ttaatataga gattattttc
     6001 ctgatttaaa gtacttaaag catttatgta tttaattatt tcttcttcat ttagatttct
     6061 attcttcatt tttacaactg atattccagt taaagaagct atgtttctaa acaaaatttg
     6121 tatatcactc atttccccac ttataaaaag tactttttta ccttgaaata ccacatttct
     6181 cattatctgt aaggctagtg ctgtttttcc tcttccactt ttggctgcta ttgtaattaa
     6241 ttcaccacta tatagacctc caatagtttc atctaaaaat tttattccta tatcgatacc
     6301 ttcttcaatt tcatcattta tgtattcaaa ggctctttct gatatagctg ttatactaga
     6361 atccttctta accaatttct gattaacttc attaacgtat ttttctaatt gatatataag
     6421 tgtattatca tctatttcac ctaatttgaa tttattaaat ttatcaatta tatttctatt
     6481 tttatatttt tcaataacta tctcaatata atgggataca ttacctatag ttggaactat
     6541 tgttgatagt tttgtcaaat aacttatacc tccaacataa tctataagcc cctttttctt
     6601 taaatcttct gtaagagtta ttatatctat aggctcatcc cttttatgta tatctttcac
     6661 tgaattgaat atatgtttgt gctcttgatg ataaaacata tcttcactta ttaatatctc
     6721 aatctcttct attttcctag aatctagtaa aatactacct aatatagatt gttctgcttc
     6781 tgtgttctta actaaattac tcatattatc cataatataa actccctacc actttaattg
     6841 tgaatcatct ggactatatg cttctgcatc tactttgaca ttaattgatt tatcttgata
     6901 attgccttct aatatcttaa taaaattatt tgggctcatt atccaatcaa aatttgcctt
     6961 ccaacctttt tcattgcttc catttaaaaa gctagtttta ctaactatat gaataatttc
     7021 taatacagtc tctttatcat attcttttat tctagcatta attacttttt ttctagcttc
     7081 tgtaagtttc tttacttttg atagttctgt acaagtaata ttgaattttt ctataatttc
     7141 actgtatatt ttactttttt cattatttac attcttgtta gttgttagtt gcttgttaat
     7201 tgcatgttga ttagtctgtt gattttcttc attagattga tatagctccc agttttcaat
     7261 agttataagc ctatttttgt ttgttgattt atttgttaga aatccatatc tttcaaattt
     7321 ctttaaagca gttcttacat tctgaatact tacatctttt gaacacatat ttgctatact
     7381 ttccaaagat gttattaact gtcctgattt aacttcatat tctttacctc cataaaccca
     7441 tttattaggc ttatgattaa ctgacagtaa taggtttatg agtatatctc tttgtttgga
     7501 attacaatct ttatatagtg ggctttcttt tatctttcta tgaagcttta tccaacctag
     7561 attactcaaa tactatcacc cacttaagtc tataatttta taccatttgc attttcaata
     7621 aaccaattat ctagtttatt ttttattata tacactctat tatctatcca tatacaagga
     7681 aatcctttat ttttagaatg acataactgt ctaaattttg attcccctat gggataaatt
     7741 ttagaagctt ctttacaagt gataagttga gctttatctc ttctatatgt ctgtatctcc
     7801 ttgtaccctt tttccttttc ttgtgcttct tgttcttgct tgacaagtat attcaatgta
     7861 gcttgtagtg ttttaagaac ttctagatta tttgtatctg ccatacatca ttcctcctta
     7921 tcaaaaaata attcttctac acttgtatct agttcttgag ccaattttaa catcaacata
     7981 ttacttggat tttttgattt acctctttct aaagaagata aataatatct tgagatgcca
     8041 actttttcag ctaattcata ttgctttata cctttttcaa ttctttttaa tttgagtttc
     8101 attgatttcc tcctttcttt catacccatt ttgtgtatcc tcatttctat aaaatattct
     8161 aacacccatt tggtgtattg tcaatatatt taagtgtatc aatagaccca tttagtgtta
     8221 taatgtattt gaggtgaaat tatgatagat aatacaattg gaaaaaagat taaacaatat
     8281 agaaaatcta taaatatgtc aagggatgag ttagctaata agattggttg ctcagtttat
     8341 gctgtagcta aatatgagca aggccaaaga aagcctagtt tagatatgat aaaaaaaata
     8401 tctactgcat tatcaattcc tataaatagg cttattattg atgaaagtga tttagatact
     8461 tcaacaaata attatactaa tttaaaagaa ttggatttag ttgtaaaaac atttgataat
     8521 tactcagcaa aactcatcgg aaataatata agcaaattta gaaatataaa taatatatct
     8581 ctcaaagaac tctcagaaaa aataaattgt tctgagaatg aaattataaa ttatgagaat
     8641 ggaacaaaaa tgcctagaat tgaaatatta aaaaaaatag cacttgctac ttatactaag
     8701 attgaagact tatttggatt tccattagaa gagataaaaa tagataacca aacaatcctc
     8761 tatagaaatc cccagactgg atatattata gataactttc ttatcgattt tataaataaa
     8821 gatattaaca tagataatac tccagtttct tattatatag ataagtcaga atttgattta
     8881 gtaattcata tattaaaaaa ttatggttat gatgtaaaaa cagattataa gacaaagttt
     8941 gaaattgcag ataatgcaga tacaataaaa ccaattagct taagcttctc tgacttcaaa
     9001 gacttctcca aaaatctaaa ttgggtgata aatggtcttg ttgaaaattt tatacaagaa
     9061 aactctaatg gtcttattga agatgaggat gaagaatatt agtattgcac attttcaaaa
     9121 tatgagttta cctattaact tttatacatt catagttaat aaataaaaat tagatatgat
     9181 atgaaaggag ctaaaatcat gaataaatca tatataccaa aatacacaca taaattccct
     9241 actaatctac ctcatggaga taaaaaatat actttaacat acattagaag aatgataagt
     9301 gaatttgtat atgatatggg taacctagaa aataacccct ttacattccc agaagtacaa
     9361 acattacttg atggtataac cgtaggtgga cataaattaa gtgaccaaaa tcaaatacta
     9421 aatataaaat catcatggga ttatgtaata aaattaagta acaaagaaaa cttatcttta
     9481 aataaagata caatttgctc tatacataaa atagttgcaa aagatgaagc tctaatagtt
     9541 ggagatttta gaaatggtaa cataggtata gctggtacta ctcaatatga atgcatagaa
     9601 gccactctat taaatgattt atttgtaagc gacataaata tcataaataa aataactaac
     9661 cccttagaaa aggctataat aataaattta tggttgtcct attgccaatt cttctatgat
     9721 ggcaacaaaa gaactgctag acttacctca aacctaatac ttataagtaa tgatatagga
     9781 gttctatcaa taccagctaa acataaacaa gaatacaaca cattaatgct aaacttttat
     9841 gaaacactag aagctgatga agttataaaa ttcttattag agaaatgtat tacattcttt
     9901 gatgaatata actataaatc atataaggag ctgtttaaaa atggcaacta aaagagctaa
     9961 tggagaaggc tctatcggaa aatataaaga tggttggcgt tcccgtataa tgattggcta
    10021 taatgaagat ggtaaaccaa taagaaaaga attttatggt aagactcaaa aggaagttaa
    10081 agataaactt gatgcttata aaaaacaata ttatttaagc tctgatattt cagatgataa
    10141 aataacttta gagcattggt tttacaattg gttatttgaa tatagaataa aagatttaaa
    10201 acctaaatca tttgaaagat atgaaagcat ctatcgtaat tatattaaag atactgattt
    10261 aggcaatgtt aaattaaagg acttaagagt atctcacata caaaaatatt acaatagatt
    10321 gcttgattcc aataaaagta tacctactat aaggcaaata aacactaaac tgaaaacctg
    10381 cttatcagaa gctgaaaaac aaggtcttat acaacgtaat tattgtacta tggtaaatat
    10441 accagttgag aaaaaggaga ataagcttga aatattgact cttgaacaac aaaagagttt
    10501 tataaaagct atagatggac ataaattaga ggtattattt ttacttgctc ttggtactgg
    10561 acttagatta ggagaattat taggacttaa atggtttgat attgatttta aaaagtctaa
    10621 tttaacagtt aaaagaaccc ttcaaagaac atattttata gataaaaccg gaaatagaga
    10681 gcttaaagta ttagagcaag agccaaagac atcaaattct tacagaactg tacctattcc
    10741 aaaagatgtt ttaaataaat tgaaagagca taaagtaaat caaaattcgg atatattaaa
    10801 ggctggagaa ttatatagaa atgataatta tgtattttgc aatgaattag gtgcccctat
    10861 tgatgataaa agacctttaa ggaatctaaa atctatatta aacagcttag atatagagcc
    10921 tataaaattt catggtctta ggaaaactta tgcgactaga ctttttgaga atgatgtccc
    10981 tcctaaaact gtacaagttt taatgggtca ttatgatata tcaataactt taaatatata
    11041 tactcaagtt atggaagata agaaaattga agctgtagaa aagttggata aaatattttc
    11101 attgtaaaaa tcaaatatat aaaaatactc tgatttcata tagttaatta caaaaccaaa
    11161 ataaggatac aaattaattt tatattatct tgtatcctta ttcttgtcta gttttttaaa
    11221 tatttatctt ggatagcctt tatgatacat taatccattt tctaacatta gttcttgggc
    11281 taaatatata tgacccttac agtgcatatc tgatataccc tcacttataa gtttatatgt
    11341 ttcagaagta tataaataat ccatactttc ttccaagctc ttacctgttt gtttagaaaa
    11401 ttctaatatg atttttttat atagcgattg taacaatgtc ttattagctt ccataaaagc
    11461 tatacctcct ctttcaaata tttgtttatc ctattttgac taactatata tttattagtt
    11521 atttaattag ccataataat tcggctataa gatatttata atctaatctc aattatataa
    11581 atctttttgc caatatttaa taatcaaaat attgcactta attaactatc ttataagtat
    11641 tgataataaa atctgtcttc ttaaatatac ttaaataaaa cttctataat tatatcaaag
    11701 tattaatatt cactctctat tgtctctcct acaagtctat tttctccatt tagggtatat
    11761 actcctgata tagttggttg tatgtatttt ctatccatat atggttcttc taaaactctt
    11821 ttttctgcta gcatcgtcca aaatacacta tatccttgtt cattaagata ttttaagaaa
    11881 atttccttat taataaagaa tcctatctct tcattaagta attcactact ttcaaaacaa
    11941 acaacttcac cataatcatt atatagaatc gaatctccct gaccatatct caatttcaac
    12001 ccataaaata gagtactaca aggtttatgc catgtgccag aaaagtcttc ttgaaatatg
    12061 tcaccttctc gttcagtagt ataactataa gttggcaata atactttata atccttttct
    12121 aagatattct tatgttcatc tatttgtacc cactcttctc cacaataata tgaattttga
    12181 aaaaagtaat atccatctgc ccaataatat tccttattat aaagagtata attactatta
    12241 ggttcagtaa gccatctacc cataaagtct tttcccttta gagcattcac tattggttct
    12301 agttggtcat ttttaattat atagctattg attaataccc acatgtcttt ttcaggattt
    12361 ttatagttct tatttttaaa atcattttcc tccttccaag tataccatcc attaagtaat
    12421 aaaaagtctt gatttttgta aacactattt accatatcat ttatgcttgg taaatcacta
    12481 aaatctccta accactcatt attaggtatt ggagaaaatt gaaataattg attatgtact
    12541 cttttattgt tattattatt tattactgtc atgacagttg gatcaatatt cctaatatct
    12601 ggctcaaatg tacccttaca ataaatttct tttttagtac cataagcatc tgtatacact
    12661 tctatcttat aattatcagc agcttgcgct gcaagttcat ataatgcaat ccattgatat
    12721 ttctttccta ttctttcata tttactatct cttaatctac cattttgtac tgttctatca
    12781 aatttaccat gtttatttac atcatatccc atatcaaaaa ctttcttaat agctatattc
    12841 tttaaatcgt tatagtctag acctttccat ttatggaaat agtgttggaa catatatctt
    12901 ccaaaatctc cataccatcc tggttgtcca tctctagtat attctacttc catagaattt
    12961 aagatagtgt tttgactcca ataataatct ttaaaatctg atgccttata gtcatactta
    13021 tatccctcaa tttcttcatc agttggtact ttaggaaaaa ttgatttata tggtggttca
    13081 acattcatat cttttaatac tgaactatca attttatatt ttgcataatc tacaatattt
    13141 tttgcataat ctcttaataa aatattggga taaacataat ctacatcaaa tattttatta
    13201 taaacataaa ctgccaatgc ctctatcatc tcttctgatt gctctgatac aacacatcca
    13261 aatgcaactg catataatcg ttcaataata tatgggtcat ctacatcttc aaatgtttta
    13321 agtaaatcta ttacaatatc cattttccct gttaatagat ttacaagagc ttttgtactt
    13381 ttatctctta agtctctatt tgaagaaatt aaaaacgttg caatcatcat agctgacaat
    13441 ctaattgttt catttgaagt attatcaaaa ccttcaaaat caaagcacca tcctaataat
    13501 cgcttaatag aagactcttc ttcttcataa acttcattaa atataggtat aaagatagca
    13561 tctctatctg ccatagtatt ttgtaaaata tattttacta tataatctgc atttaatgta
    13621 tgattaacct ttgtagaaat taagataagt acattataaa aatctatttt ataataagat
    13681 ttacctaaaa ctattttatt aatataatct agtgtttttt cagtaattgt agatttctta
    13741 cgccatttta gtgcattgat aaatgcacta ataacattat aatttgtttc tttattttta
    13801 aaaacttcaa aaatttcatt aggtatatct gagcctgtct cttcagataa aacaattgcc
    13861 aatacttcta atatatcctc atattctact aaatatttat acttatgtga aaaatctact
    13921 accccaattt cttttaactc tttaaccaac aaatttgcat ataaataatc ttctaacttc
    13981 tcatatgtca catgcatata ttcttcatca tttaaattga ctgttttatt aactattcca
    14041 tttgctatga gttcatctat tatcacattg ttaatcttat acttacttgc aatatttatt
    14101 ataatctcta cactcttgtt tgcgggtatt aaattattcc caagaccatc tccatattta
    14161 tatttaatca tttcattaag tacttctgta actacattgg catgtctact ataattgcat
    14221 gattcagata ttctaagatt aagtatattc aaataatttt tataaatatc tgtaaaacta
    14281 atagtatcta agttaatctc ttctccttta aaagtttcac acataattct caaaaaaaga
    14341 gggtttctaa attcttgatt tggcattgga atattagaat aaggtattcc ataataatca
    14401 aaatactttt tcatagcttt atgttctata ctagaaaatc cttgatgctc tataaaaacc
    14461 aaattctctt ttatcttgtt attattatct attaaagatg gtatatattc acttcttatt
    14521 gataatatta gtccaatcca tggatatttc tttatctgtt ctacaatacc atttaaataa
    14581 tatttccaaa gttcttttcc ttgaccttca ttcaatgcat ctataaataa tatcacacgc
    14641 tgttgctctt tttctcctat ttcattaagt atttctaata attcttcaaa ctcacactca
    14701 atttctaata tttctaacat atgtttaatt ggtgttttat ccaacttaaa atgttgccct
    14761 aaaaataata tagacttatg cccatccata tttcttttct caatagtatg tgcaattata
    14821 tgagatttcc ccataccacc tgcactatgt aataaaatat aagggctatt aactactttt
    14881 atttccttag aatccaaata ttttatatat acatagatat ctttttgagt ctgcttcaat
    14941 ttgtatattt catcttctct ttttttactt ttttcacagt cttcatttat aattatattt
    15001 ttaaaattat ttattctatc atcaagtgct gcacttattt tttcaaagtg cttttttaac
    15061 aacttgatat ctaatctttc attagctttg tcataaaatt gttgtattat ttcttctata
    15121 actagtacat ctacttccac ttcatttatt ttctgtttct ttatacttga tagaacttta
    15181 tctgtttttt catcaaaacg ttgtttaaat tcttcatttt ttcctaatgc attaaacgta
    15241 ttttctaaac tcaattctac attcaattct ggtaaatatc tatctccaag gttttttatc
    15301 tgtatattat tctgattttg aaaccatttc tctgttaatc tacaagataa attagttaac
    15361 ctactttcct ttaaagacct atcctttaat cttctatatt catctggcaa aactatttcc
    15421 aaaattcgtt caagtattat tcttacacac tcatgcttac cttcaggata cataatggtt
    15481 tgtatataat actcattttc taactctatt cgtctatgtt tctttttctc actactaact
    15541 ggaataatag cataatgacc cgttcctgcc tctgatactt gctgtaataa ttccaacggt
    15601 ctatcctttt ccaaactaca tccaagaaat aacaactctt tacttgtata tacttgtgta
    15661 agcatctttc tcaattcatc attactatat gctttttcat attgttcttt tgttaacaca
    15721 atagatgttg taggctctgt aatatcccca tgaattttat acaatactaa ttcattattt
    15781 ctaagtgcat tatttaatgc ttcaaagtga cctggatgtg acactaaaac tgttttattg
    15841 tgtaatccat aatttttttc tagtacttta tcataattag tagttataat taatcctgag
    15901 ccaaaaatta taggaattaa atagacacat ttatcaataa aatcgtcttt atcttttgca
    15961 tccagataac ctgccccaaa aacttttttt aaatgtttag aaaatctaac tttcgccaat
    16021 tcttcatata aaaattctgc ttttttctca taatcctcta ttttttcaaa taaaatttta
    16081 tcctcatctt ctaaatattc ttcacttgtg ttatttaaaa atgtactcca tgaaggatat
    16141 atgtctttaa ataacataga catgcctgct ccaatatatg ggactacata accatcttta
    16201 attgcattta ccagttcatc aaaatttttt tgattgtaag gcttattaaa ttccataatt
    16261 tcttcaaatg tcattattcc ctcctaaact atctcttaat aatttcaacc ataattccta
    16321 ttttataatt ttattatatc attccattcc atttttttac tacaattcta tgttatagaa
    16381 tgaattcact tacttacatt tgttaataat ataaaacttt cttttaagat aattaaaatt
    16441 tatactttta aattatggat aaaaatggaa tgttataact tttaatgtat tactaatatt
    16501 aacaatttta aaaaataata ctattcttat tttatgctat aattatattt tgcataaata
    16561 ttattgatat tttataaata taattatact tatatctcat actcaaatat tttatataat
    16621 atataagtct aaattaactt gcaatataaa agcgcctctt aatataggtg ctataatgtt
    16681 ataaattttt aattatatat tccaatgaac ctttatcaac catatctaaa ttaaatatat
    16741 aatccatctt atcaaatgca tctcttaatg gaatacttga ttcaagccat cctaacccat
    16801 ctgtaatcca acaaaatgta aaacctccat cttttatata cttatctaac ttagtaaact
    16861 catttgcaac agattttaac ttagaacctc caccattata aaaattaact tctactaaaa
    16921 caatttttcc attattattt atagcaaagt catactttct tttactctta tctgttggaa
    16981 cttctataga ccatttctca cttatttttt tcactgtagc ttgtgttaaa taactccaat
    17041 tattcttttc acacatattc tttacatatc tttctacaag agtttccata ctacttccag
    17101 ttctattttt tctagcattc gtatcaagcc caacctctac tccaaacaca taatctacta
    17161 aattttttat atttttttgt tttaataaat ctaaaaactt tattttttta agaaattctg
    17221 tagctaattc gctttcttca tcacttatac tctttctctt cttaaaatta aacagtttat
    17281 atttaaacat atcctcatct gatggatcta gtattttgaa ttcattatct ctactcgcta
    17341 ttactattgg tatcacacta agaacttctg gatactcttt taataaattt ttagtttcgt
    17401 tttctatatc ttcttttcct ataagatagt ttaagatatt taactgaacc tctatctttc
    17461 tagtattttc caaagcttta ttccagttaa cataataatc ccagctagct atagtacctt
    17521 ttaaattttc aagtaattcc ttaaatattt catccttact cttattttta tgaatattct
    17581 taaccaattc catttgattc cccacctctt cataattagt aattagcaat tcagttataa
    17641 aacctcttcc attcccctta gaatttatga atcttttagc atgtactctt tttatattaa
    17701 aatctgaata caaatcatca aagaaagtat cttcttcatc taaaactttt ggatcagaat
    17761 tacttaacat caattttgta tctattttat ctagaacttt ataaaattta cttaactcaa
    17821 tttgactatc atcattaaaa ttacctttgt tataggaatt aaatcctcct atagttactg
    17881 gtctatatgg tggatctaga tacacaaaac aatttttatc tattatattt tctagattta
    17941 aataattctt atttaatatt tttactttta gctctcctcg agaatctctt ttatttaaaa
    18001 gcatggataa tttttcaagt tcatttttat caaaaaaact aggattttta tatcttccaa
    18061 aaggtacatt aaattcacct cgagaatttt ctctatataa tccattaaaa catgttttat
    18121 ttaaaaatat aaaatatgaa gcttgcttta tacaatcttc attttctata tttttttcat
    18181 ttgtaagtat attaaatcta tctctaatat catagtacat cttttctcta tctgaagaac
    18241 cttcttcgta agatatgtat tgttctttta aattagttag ttctgttatt aactcttcca
    18301 aatcatctct gactttaata tataaattaa ttaacttact atttatatca ttaattacat
    18361 acttgttgaa aatgtcctct tctaacaaat atagaaatag tgcacctgca cctacaaaag
    18421 gttctatata agtcatggaa ctaaaatcac aacctgtagg catttgtttt cttagaatat
    18481 caagtagctg tgttttacct ccagcccatt ttaaaattgg tttcatgcaa cacctctctc
    18541 agttatattg ttatataatt atataaaata agattctaaa atacaagtac tcatcagaac
    18601 actatattta tatcaaatct ttccaaaatc taagtattat tttatcctaa cacttttcaa
    18661 aacctctaaa taatatacaa tattctctaa tatttactta ctaaaaattt aaatctatct
    18721 ttaagtataa cctaaaacag attataagtt acgtagtttt taatataaaa tatacttcta
    18781 caagtaaagc tttaaatatc aattacttat ttcataatta atgactatgt accctcaaaa
    18841 aaacctcatt ttctatggtt ggggtacggt tggtggattt catcaccaaa ataaaaaata
    18901 ctagtcaata aagactagta tttccaagta tttcatcatt cttttttcaa aattggtgga
    18961 gacgagggga gtcgaacccc tgtccgcaaa tcttttcctt gctgcatcta catgcttagc
    19021 caacttcact aatatctcac ctcacatagc gccaagtggc aggctctatg cttagccagt
    19081 cccaattaat ctacttcagg tcgagacacc cctaaagtag ttccctgcat aatgacgtcc
    19141 agtcttagtc ggcaggagga ctaagaggga cgagcagcaa ctaggctgct atcgcgaaat
    19201 tatcgtctgc gtttatttta aagttcccca gtttttacgt gacccagagt aacacgacat
    19261 gcagcctcaa gttccaaacc cacgtcgaaa cctttacgcc cccttgagta gtttatagtc
    19321 cagtagactt ttcgcaaact ttataaccat ttttattaaa tttttaatgt atatataata
    19381 taatactttt aagaataaaa atcaatgtta tgttctagat aataaagaat tttattctaa
    19441 aaaatacagt tttatctagt ttaatactta cctgtcattt ctctttctat acgtctttgt
    19501 gcatctttct tagccatatc ttgacgttta tcatatagtt ttttaccttt tgctaaggca
    19561 atctctactt taactttacc gttttttaga tacaaactaa gtggtataag tgaatacccc
    19621 tttatagtag ttgctccaat aagctttctt atttcatgct tatgaagtaa tagttttcta
    19681 actcttaaag aatcaacatt gaatatattt ccttgctcat atggacttat atgaacttgt
    19741 tttaaaaata cttcgctatt atctacagat gcaaatccat cacttaggtt aactttgcct
    19801 tgtcttattg attttacttc tgttcctttt aattcaattc cacattcata agtttcttct
    19861 ataaaatatt catgtcttgc tcttttgttt gttgctaata tttttttacc agccatataa
    19921 atctcacctt ctttgctaga aatttattcc ataaatatta gaaatttact aaatatttaa
    19981 tgttgccaaa ttatttgact aacttgtatg ataacatatt taggcatttt agtcaatatt
    20041 tcactgatat attaagttag ttaggctata tataattaag taatataaat gtatgaaaat
    20101 agctaaaaaa ctacttcgaa tatacttaat actaaactaa ctctaaccag taatactaat
    20161 ttataaattt caaaacaaaa atattacata ttataaatct tctatcttct atcttctatc
    20221 ttctatcttc tatcttctat cttctatctt ctatcttcta aataatttta acatgcccat
    20281 aaaatataat acccacaaat gataaataat actcaaaatg tctattgaaa taactataca
    20341 tccttaaata acttaactta aatctaaaca tttcaaaaac ttcttaaaaa tatgtaaaaa
    20401 tttgatgata aagtagcgat tttttcaaaa aaaatgtaat atagagttat atcttataat
    20461 attttagaga taaattttat catagtgggg agaaatttgt atggatttaa gcaaaaaagt
    20521 aaaaatttta gaaaatgcat cagatggcaa aagcgaattt gagatattag aatttgaaaa
    20581 acttgaggga gcttctagcc cattaatggc aatgggatta tattttgcta gagaagctgg
    20641 tttgaaagct agacaaatta agataaaatt aaataattca tcaataaaaa cagaagctgg
    20701 tgcattatac tattataaag gaaatatatc ttctgaaact aagattggtg gtgttggagg
    20761 tctttttaaa aaaggaatat caggagcact tactaatgaa tcaatgatga aacctgtata
    20821 caaaggtact ggagaagttt atttggaacc ttcttttaga cattatttat ttatgagtct
    20881 tgataatgat tctataattg ttgataaagg attattctat tgttgctctg atacaataga
    20941 agtaaaagca tttacacaaa agaacttctc atctgcttta cttggtggtg aaggcttctt
    21001 ccaaatagaa ttaagtggta ctggtgtaat cgttctggaa tgtgttgtac ctcaaagtga
    21061 aattgtagag tatgaattga aaaatggtga agaattaaag gtagatggta actttgcaat
    21121 agcaagaaca tctggtgtta atttttctgt tacaaaatca gataaatctt taattggttc
    21181 tgctttaaat ggtgaaggtt tcttaaatac atttactggt aatggtacag tttggctagc
    21241 tccaactcaa gtaatgtatg aaaaactaag ttttggagca atgcctacta atgataatat
    21301 gaataataaa gtttctaagc aaaaatagtt gttttataaa tatttattaa atcattattg
    21361 attttataaa gtcactataa attttattag attattatta taaaatcaga gtgtggaaat
    21421 gtttatgtgt attctttaaa taaaaatttc cacattctgt aaggttatta tacttgatat
    21481 ataaaattca atttaggaac atagtctaac atttataaac atattaaggt aatgatttct
    21541 cttggtaatt attctcatat cttattcttt gattatattt atcttattcc tagcccttat
    21601 gtcatattat atttcttatc ttattactta taattagcat taacttatct aaaatcttgt
    21661 atttttttaa tagtaaagtt tacatctata ttaaaaagtt tacatctata ttaatttcat
    21721 aaaacaatca aggtagtcaa gagattcaac tttacttgat tttaaaaatt taagtgaatt
    21781 tgttcttata cacatctttt taaaattata tctgtagaaa atatcattta gagctataat
    21841 taaattaact tattaaattt tagaaaattt attaaaaaat ataagttaaa ttaatatttt
    21901 taaagattct tttttgtaac tactagaata gtaatttagt agttattgta tctctaaagt
    21961 ttaagcatgg atagatatac atttgataat ttgcctataa tttacctact acttggatta
    22021 ttggagcaaa tacaatatat taataataag ttcctaaaac caataaatta actaatacac
    22081 ataaagatat tgatgttgat tatacaacta taagaaacgg atttaacaga atttaatcaa
    22141 gctaagaaat tatatatata tcgtgatgtt tttgaattag aaggtaattc aaaattagtt
    22201 tatagtcttc tgtcaatcca ataaaaagta cagggtacaa gaattgttag taaaattttt
    22261 aaagatttta tggataaata taaatagttt tacttatttt ctaaaacttt aaaataccat
    22321 taattacctt aaatatttta ataggaggac atatgaattt aaataaagtt aaatttactg
    22381 aagaacatgc tattgaagtt actaattgga aatatgaagg taaatattca atatacaatc
    22441 tacctccatg ggaggaaatt aaaaagaaga atttttcact agcaaaagaa gataaaagaa
    22501 aaaattttat aagttttata aatgacaata aagaattgat aggttttata aacttattag
    22561 atgaaggaag ctctgtattc tttggtattg gtatgaaacc gaattattgt ggaatgggaa
    22621 ttggtaaaga aataattggc ctaggattac aagaatgtag aaataaatat agtactaaac
    22681 caattgtatt aaatgtaaga acctggaaca tgagagctgt aaaatgttat gagtctcaag
    22741 gatttaaaat agttgagact aaggtacaaa aaacgcattt aggagatgga gaattttttg
    22801 ttatgaggta tcaatagttt ataacaatag tcttattgtt aatacaacaa ttaaaatgaa
    22861 aaaatacata tgtgtaggtc atagcaataa gtgtctttga aatataaatt tgagagcttt
    22921 tgataaaatt ttgtatacat atatatttta tactacggat atataaatct atctacatat
    22981 ataaagagat tgtaagtagg tttgtgtata taaaaataga tttatatttc ataaatgtac
    23041 tttttatttg tattaccttt attttatcta agctctcatt ttattatcta atcttccttt
    23101 ttactggttt tattaagaga gatgcaatta tcaacacaac acttccaagt atcagccaat
    23161 atttctcatc aaaactacct tgactcatag acattataaa aaattttcca acatacttgc
    23221 ctttagtcat catatttaaa attaaatatc ctatagatat catataacct atgattgtat
    23281 tattaaataa atttgagaaa aacattccta aacttcctat aaacatagct gatgcgaaac
    23341 ttccaataat atactcaact actggaaaat tacatccaag atatattaaa acatttacaa
    23401 aacctatgat taataccact atacctataa ttgacatcag tatcctaatt aattgtacaa
    23461 taacttgaga taatgctttt gaagatacta tctcatcaat ttcttttgat tgctctagcg
    23521 aaaatacagg taccaacatt actatcccta ttattgcaac ataattttct aaacatatag
    23581 ctgttgaaat tctgtctaaa ttagctactc cttgtattag aggaaccata catagcaata
    23641 taattgaaca tattaaatta gttaaagtgc ttaatttgaa gttttctttt attagaacta
    23701 aacagttttg aaaactttgc ccaaacatca agattccccc ttcttttttg ctcatataag
    23761 aatatagcta acaaaacaag caccaatgct cccaagctta tcacaattct attaatcata
    23821 atttgattga agttttgtat aataatatcc ccatttaata cactattatg tcttatcatt
    23881 agccccattg ttgaataatc acctttgagt cctgtagaat ttatactgta aagccaccaa
    23941 attaattgca caataattgc tactggtgta tctgttaata tagtaatact cattcctaca
    24001 gctgtaacta tcataagagt tggtagtatc caccataatg tatattttat aaatgctaag
    24061 ttatcaatag atataccttt atctttagca aagaaaatca aaggaagtaa atctttcata
    24121 cctaaaatta atacaggcaa tatcatcata aagacaagtg caaaatatct tgataaaact
    24181 attttgcatg aagatacttg ttttgaataa ataatctctc tcattcttga acgcttatct
    24241 ttaagtgaca taaaaactgc cacaaatact ggaaatatac ttaaaactat acctatataa
    24301 tcgcaaaaaa ttcttgcata cccattacta actttatctt tttgtattgt atagttgtaa
    24361 ttcttcatag cttcatcata ggtaactgga actactccaa atctttgtaa cttgtcaaaa
    24421 gcatatgcag accctcctcc taaaatgtcg tctactcttt gcattatttc ttcaaatctt
    24481 tcaagagata ctttagaata atctattttt atactttcat cagttttcca aagtgaattt
    24541 atttcgctaa tacttttacc agttatttct tctatatatt tttctatggt cttcgtttta
    24601 ttttggtcta attttatata cttaactacc cctgttggat acgttgtata tgtgtttttt
    24661 tgatattctc taattaggtt tatagttgca tttggaatga ccttttctgt tttcatagat
    24721 tctttttgac catatggata ttgattgtgt acagaataat attcctcaat attctctact
    24781 ttttgtggag caactaatgg atttccatca ttaggaatat ttttacttac atcatttgaa
    24841 actgaacttc caagttgaga aatatagaaa aaaactaaaa ctacaataaa aatataatat
    24901 accatactct ttaatatatt tttacattct tttataaata gattcatata ttatctcctc
    24961 ccattataag catatagcca tcttcaatag ttggattaca atttactgct gtctcaaaag
    25021 gtttatcatc tgatataatc ctaagtatag cctttccacc atgagtcaac attcctataa
    25081 ctataaatct actttttata ttttcaatgt cttttttatc tacttcaata ctatatactt
    25141 tcccttcagc tagttttgct aatgcttctg ttgagccatt gtatatgact tttccactat
    25201 tcaatatagc tacgttttca catgtagctt ctatatctcc aacaatatgt gtagataaaa
    25261 taacgattct atcatttgca atttcgcata gtaaatttct aaatcttata cgttcttctg
    25321 ggtcaagacc tgctgtcggc tcatctacta ttaaaactct gggattatga attaatgctt
    25381 gtgctatccc aagccttcta ttcatacctc cagataaaga ttttactttc acattttgat
    25441 aattagtaag gtttactttg cttaataact ttgctataat ttttcttctt tttcttagtg
    25501 gtatatccga taaaactgct aaataatcca ttgctttata tactgtcatg ttaggataca
    25561 ttgaaaaatc ttgtggcaaa taaccaacca tatttctaat ttccttagta ttctcaatag
    25621 gaactccaca catatgtatt gaaccttctg tttttgataa taaagtggct aaaattctca
    25681 taaatgtggt ttttcctgct ccatttcttc ctaaaagacc aaacatacca ctgtcgattt
    25741 caagatttat attatcaaga gcttgttttt tcccaaatct tttactaaga ttggatactg
    25801 ctattttcat ttccatatat aaatacaccc ccagaaacaa ttttatagaa ttttattttt
    25861 ataaattttt actgtatttt cataataaat
//
LOCUS       DAYAOO010000053        25644 bp    DNA     linear   BCT 12-OCT-2024
DEFINITION  TPA_asm: Clostridioides difficile isolate ST8-SSI-h139-18
            SAMN40601845-rid21577343.denovo.053, whole genome shotgun sequence.
ACCESSION   DAYAOO010000053 DAYAOO010000000
VERSION     DAYAOO010000053.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN40601845
            Sequence Read Archive: SRR28438827
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 25644)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 25644)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-MAY-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-MAY-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002157583.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002157583.1
            Genome Coverage       :: 163x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/11/2024 16:19:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 4,038
            CDSs (total)                      :: 3,963
            Genes (coding)                    :: 3,930
            CDSs (with protein)               :: 3,930
            Genes (RNA)                       :: 75
            rRNAs                             :: 6, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 60
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 33
            CDSs (without protein)            :: 33
            Pseudo Genes (ambiguous residues) :: 0 of 33
            Pseudo Genes (frameshifted)       :: 7 of 33
            Pseudo Genes (incomplete)         :: 25 of 33
            Pseudo Genes (internal stop)      :: 11 of 33
            Pseudo Genes (multiple problems)  :: 8 of 33
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..25644
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN40601845-rid21577343.denovo.053"
                     /isolate="ST8-SSI-h139-18"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Denmark"
                     /collection_date="2018"
                     /collected_by="Statens Serum Institute"
     gene            67..813
                     /locus_tag="ACGI5H_002447"
     CDS             67..813
                     /locus_tag="ACGI5H_002447"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891335.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2087 domain-containing protein"
                     /protein_id="HFG9698147.1"
                     /translation="MKIENLSIDDIKRGYIFNDDLNCYSCIKCTKTYEVGEIYKIGNR
                     FFEASKAIELHMELEHSDYLEQLLNSDSKYNTLTENQKQLFQLFISDLPDKEIAKQVG
                     VSTSTIRHQKFIFREKAKQAKLYLALYESVFEDKSNKSSTIIPIHEHARMVDERYVVT
                     EEERKHILDTSFESMNPLKLKVFSSKEKKKVVILSKILEQFERGKKYSEKEVNQILES
                     IYDDFATIRRYLIEYGFMSRNKECTKYWLT"
     gene            874..1548
                     /locus_tag="ACGI5H_002448"
     CDS             874..1548
                     /locus_tag="ACGI5H_002448"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861786.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4Fe-4S binding protein"
                     /protein_id="HFG9698148.1"
                     /translation="MNDELKSILYNKGVDIVRFVDISEFPINQTQGFSKAILFCIGLS
                     KKFITDIYNNLPTDSDEFLEKEEKAEELADWISEYIQNKGYRAYSQSEKNNLEHGYFE
                     KAYINPEMQSGISPLPHKTIANISGIGFMGKNNLFVTEEYGCAFSMCTVLTDAPISVE
                     RYPLIDSKCMDCNVCVENCPAKAIHGNEWTLPGKRESIIDVSKCFCVLKCMMSCPWSL
                     RYANQK"
     gene            1916..3262
                     /locus_tag="ACGI5H_002449"
     CDS             1916..3262
                     /locus_tag="ACGI5H_002449"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898101.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 55 protein"
                     /protein_id="HFG9698149.1"
                     /translation="MEIETKTPDWINVLELNSKIDITGKYDVSNIIQDIVSDKSLEGS
                     IIYFPKGNYLFEKGIKISQQITLQGDSYYGGDNQVSNLDKKQSIIGTTNFITRGVSNM
                     SIIALTGTSQCIKNINFYYDSHDIEKIPPKNVSAITEYGETQGLSHFEHLFISGFSGI
                     GIEIPYYSTGNDIIVSSCGLGMRLGEKSMLSSSKIYECKNGMEITTGVSLNNVRIEEI
                     KEIGINNKGFGFNLIMNLMVDQCGYCGFMFEKMCYSQITARITRCGQYYKSVDYNAYE
                     NMEDRKEKAYSIFYGDILESCNIVLMNRNIDTLESDSLNEHKIYVIKANETNNVMLTC
                     YAEADNFIQCAKGNLLLENGENTYKFYNGEICSVGGVQISDIDEKDLIKIIENTLYID
                     DKGKYLMVPRLKKNTVIYSVLDSTEEINKLHGGIWEQIDVKVLAGESMYYYKKIKD"
     gene            3289..4689
                     /locus_tag="ACGI5H_002450"
     CDS             3289..4689
                     /locus_tag="ACGI5H_002450"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903406.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyl hydrolase family 28-related protein"
                     /protein_id="HFG9698150.1"
                     /translation="MEESIIIKDISGWINVLDYGICNDETKDVSFKLQEIMDAVPEDS
                     IIYFPKGKYLFESGVKIKKRLTLCGDSYILANVPKNTAGVTQFTFKGKKNPKSENRAI
                     ITAKSVRHCIKNICFYSDSCDRDMTSNHEPPTDGKPRFHHNVIINYRNISAVICEDKQ
                     GEPGHYENLSFSGFSGIALDMPNNSTANDITIFTSGLGISTGENSTIANSKVWGCVDG
                     MIISTGTFINGMRVEEIKKVGIKNIGRGLNFITNITIDQCGYCGVWFDSISNVQISGN
                     ITRCGQYYYDVSYDNYLMLDNRVKEAYSLFYGNLLESSNIVLSNTNEDNWEDFKEDKH
                     KVYLIEALKTKNVLLTCNIDATDWIVKSEKGNLTYNNMRQTVIFYDGKLSSINGIGIS
                     DEDYGDKVKIKKGNIYINSNDKDIKMHKPEVGDIMSTIIKDKSILSAHYGGTWEKIGE
                     KIEFGITVHYYKLIEK"
     gene            4899..6335
                     /locus_tag="ACGI5H_002451"
     CDS             4899..6335
                     /locus_tag="ACGI5H_002451"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898097.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 55 protein"
                     /protein_id="HFG9698151.1"
                     /translation="MEGRTGIKDGRWINVVERGIKNDGSYNIGPALQDIIDEIETDFC
                     VLYFPKGKYLFTSGVKINKEIVLQGDSNSSTGTTQFITRGVENMSIITLTGKKQCIKN
                     INFYSDSCEIQVNKEPPTKGNPKYHYEMIINKNEKNVEMNNVSAILYDNSKNMIKGLG
                     HYENIYISGFSGTGIRIPYYSIVNDITVSSCGLGIDTGIDTIISNSRISKCQNGMRIR
                     TGTSINNVRIEKIQKVGLISSQVKGYEGYGSYKINNITIDQCGYCGFSFDSMKDSYFS
                     GIIRRCGQYYYNTDYDTYLSIKDRVEEAYSLFYGNYFTECNIDLVSDNKDNWDDGLEY
                     KHKVYVFKTLQIPKLTLRCNIDAYDYIVKSVHGGGNLMLKNNFNNYIFIDSSNPEVIN
                     GINFNYQKNGNLLRLNNGKLSYKNGKEETAIFRPNYGLIVASTDSECEQIEATYGEKW
                     EKLGSEVIGEETVYYYKHHEPDKTNQIQ"
     gene            6679..7623
                     /locus_tag="ACGI5H_002452"
     CDS             6679..7623
                     /locus_tag="ACGI5H_002452"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728993.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1848 domain-containing protein"
                     /protein_id="HFG9698152.1"
                     /translation="MIVSVSRRTDIPAFYSKWFFNRLEEGFVYVINPMNPKQVSKIEL
                     NPHTVDCFVFWTKDVTPMLYDLNKLRDYKYYFHYTITSYGKEVETCILDKRKVIDSFK
                     ELSRKIGKERVILRYDPIFLSEKYTVDYHIKAFASLCNQLDGFTEKCIISFIDLYKKT
                     KFNTKALHIKPIEITEIETLSKEISKIAHKHGIILEMCSEEYNLSKFGIGKSKCIDDR
                     LISKIIGCEVEVKKDSTQRDICGCVKSVDIGQYNTCRHYCLYCYANFNYAKVEENCRL
                     YKEDNKLLIDTLRDDAKISIRDMKTIKVDKNKQISIFD"
     gene            7792..8724
                     /locus_tag="ACGI5H_002453"
     CDS             7792..8724
                     /locus_tag="ACGI5H_002453"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018112805.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TDT family transporter"
                     /protein_id="HFG9698153.1"
                     /translation="MNLLKKYPIPIASLILSIFTLGNLLQSYSESLRNVIGFIGFILY
                     AIYIVKIILLRKGVKEQLENPLISSTFPTITMATMIFATYIKPLSLELSIMIWSIGIV
                     GHLVLIVLFSKKFLVKFSIKTVFPSWYIVYVGIVAASVTAPAFNQLLIGKIAFWIGFV
                     SYIVLIPVILKRVWIIKEMPEPSLPSIAILAAPGSLLLSGYINSFSDKNNVVLYLLFI
                     LSIVFYIIVLGYLPKLLRLPFYPSFAAFTFPMAISAMGMKLMNGYLTKSGHFISWISY
                     ASKLEEIIATVIILYVLVLFIIYLSKSETTSKAK"
     gene            8829..9296
                     /locus_tag="ACGI5H_002454"
     CDS             8829..9296
                     /locus_tag="ACGI5H_002454"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003431999.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="C-GCAxxG-C-C family protein"
                     /protein_id="HFG9698154.1"
                     /translation="MKTKEEYLKEVRNISEEYFRKGEFFCSEAVLQTINDALGQPLSP
                     EITKLASGFPIGLGKAQCLCGAISGGEMALGIVYGRVHGEAMNPKMFEHAKGLHDYIK
                     KEYGATCCRAITKKWDGDNFMSPERKEHCIKITGQVTEWVADKLIEDEKLNIK"
     gene            complement(9540..10394)
                     /locus_tag="ACGI5H_002455"
     CDS             complement(9540..10394)
                     /locus_tag="ACGI5H_002455"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GRP family sugar transporter"
                     /protein_id="HFG9698155.1"
                     /translation="MLTIIIALLPVMGWGLMPIVANLKKSSPHEQLLGTSISAFIFST
                     IITLVIHPEITFFSFCISMISGIFWSLGQLMQFKAIQIASVSKVMPISNGSQLTFTTL
                     LAVILFNEWTSSKMLLIGSLSILCIILGILLTNYQTKKSTDKNMLKCVGVVLLSSLFL
                     SLYVVTNQIFLIEGYRIILPQSVGMLITSSIIVKYFSKEIVYRENVLFNLITGILWSI
                     ANLGMFITTNTLGVTISFSISQSCVIVATLGGIIFFKEKKNKKEWLAIFIGIILIMSG
                     VFMLSIIK"
     gene            10560..12524
                     /locus_tag="ACGI5H_002456"
     CDS             10560..12524
                     /locus_tag="ACGI5H_002456"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018112804.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antiterminator"
                     /protein_id="HFG9698156.1"
                     /translation="MLTDMIQNREIKIIKFLLKEGHTTVKAIADDLDVSEKTVSKSLK
                     EVEAVLKKIGLSLIRKPKIGVYIDGDLKKILPYLDNKGSQIPTTREERVIYIYSVLLK
                     SNDYITIQQLSDELYISRGTIERDLAEVEKLLKNEGISIYKKPSKGIKLNISERDKRQ
                     LTAKFIHKFWSRNWYIKQEQESFYQAFEKIQADVNGIFSEDDLSIIIDILRNFSRERK
                     FEFSDYEFQSLVIHLAIAVERIRKGEYIEESLYTGNIENNQMSNTNYLAKQLEEKFSI
                     LLPKSEIGYINLHLVASDQHRDTNELKNTSTNPCETSTNNISNLREIIKNTLYETAYD
                     KDLIDGLTSHVHSSINRLKYGLSIKNPYVNTIKQNFSLSFEQALDLKKVIEFIYDIRI
                     NDDECAYIALHFEAFRERMKELPQNIRVILVCSTGLGSSRLLSARIKKYFPMIKIEKV
                     LSVQELVSSKIDADLVISTIYLELETIPTIVVSPILNESDIRTLERNIQNVSSYTSKK
                     YKSFRNLIFEENILLNIEASNYEDAIKYITDNLIKKGFAKEGIAKSAIERENLSYTSF
                     QSIATPHANPSYIKKSNISVATLKNPITWGNEKVEVIFFISLENDKNLELDEIYEVFY
                     DFIDNKKNINDILSATSTKEVYDLLVEESI"
     gene            12524..12985
                     /locus_tag="ACGI5H_002457"
     CDS             12524..12985
                     /locus_tag="ACGI5H_002457"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422574.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:1902495 - transmembrane transporter
                     complex [Evidence IEA];
                     GO_function: GO:0016301 - kinase activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA];
                     GO_process: GO:0016310 - phosphorylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HFG9698157.1"
                     /translation="MKISDVLKKEQIVFNLDTNTKEETIKKLSSIFVENGIVDNEEEY
                     VKSVLEREEHSTTGIGNGIAIPHGKSNAVKKSSIIFAKTKHKIEWDALDEKPVDSIFL
                     LAISNIDKDSNHLVLLSKLATKLMDDDNVDALKLANSEQEIINIFSEEGEM"
     gene            12988..13308
                     /locus_tag="ACGI5H_002458"
     CDS             12988..13308
                     /locus_tag="ACGI5H_002458"
                     /EC_number="2.7.1.202"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422575.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016301 - kinase activity [Evidence IEA];
                     GO_function: GO:0022877 -
                     protein-N(PI)-phosphohistidine-fructose phosphotransferase
                     system transporter activity [Evidence IEA];
                     GO_function: GO:0090563 - protein-phosphocysteine-sugar
                     phosphotransferase activity [Evidence IEA];
                     GO_function: GO:0090582 -
                     protein-phosphocysteine-D-fructose-phosphotransferase
                     system transporter activity [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA];
                     GO_process: GO:0016310 - phosphorylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS fructose transporter subunit IIB"
                     /protein_id="HFG9698158.1"
                     /translation="MKRKIIAVTACATGVAHTYMAAQALKKASKKMGHLIKVETQGAT
                     GIDNELTTKDAQIAEVVIFAVDTKVRNAERFEGKEILEVPVNAPIKDAEKVINDALKL
                     IDTK"
     gene            13324..14424
                     /locus_tag="ACGI5H_002459"
     CDS             13324..14424
                     /locus_tag="ACGI5H_002459"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891322.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS fructose transporter subunit IIC"
                     /protein_id="HFG9698159.1"
                     /translation="MLKKIVSELKKHVLTGISYMIPLVIAGAMIMAISRVGGSFYNIP
                     DIWDAKYAESASSIVRLLHDLDGFGGTALGLMFPVIAAFIGFSIADKLAIVPGLVGGM
                     IAKDIGAGFLGALAVGLIAGYTCLFIKNHVKLPKSAASIVPIFIVPVFGTLITVVLIN
                     YVIGIPFATLNTGLENWLNGLSGTNQILMAAIIGAMMAVDLGGPVNKAALTTSLALLT
                     SGIYAPNTAAMVGIVIPPLGLGLATILAKQKYNKQLREAGKSSLIMGLIGVSEGAIPF
                     AVESPLKVIPSCVIGTAIASAMAVGLGSVNATPISGFYGWFTVENWPMYVLSIAVGTV
                     IVAGLVIVLRGNPVIEDDEFEDDDFDEAEWES"
     gene            14544..17144
                     /locus_tag="ACGI5H_002460"
     CDS             14544..17144
                     /locus_tag="ACGI5H_002460"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903397.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-mannosidase"
                     /protein_id="HFG9698160.1"
                     /translation="MIKAHIVNHTHWDREWYFTSGDALVLSEQLFTDVIDELERNPDV
                     SFVLDGQLSILDDYVQLHKEKIEIIKKLIKEDRLHIGPWFTQTDAFFARGESILRNLM
                     IGIFESKKYGKYMKIGYLPDTFGFNAQMPILLKHVGLDNIFFWRGIHLGKQVQSPYFK
                     WKSLNGESYIYAVNMPHGYGTGMLLEPSLKYVNGRLDPAIDFIKSYTDVDEVLIPSGN
                     DQLNIIGDFKNKIKAINDIGKYSYITSSYQEFLKYIKSIESLESYRGEFREPVLARIH
                     KSIGSSRMDIKLACDKLENKLIKRIEPLLVIAKKSKIEISNQLLINTWKKLLEGQAHD
                     SLAGCVTDTVTDDILHRIREANEICDSIENTIVKKISEGLKLSKNDILVFNTEAKRFN
                     GYKEIQVVSDSKNIYFKDNLDATIIEETYVKPRENVLEETPAGNIFIEEPGYYILKVR
                     INVQLPALGYKVVSFESSDKEMVSLNKSNDAFISNDNYKIIYEDGSLNLQLKDGTYIS
                     NFLTLKDSGNAGDTYDFSPLKNDEDIKLSFDKVYTEKALGYEKMVVKGTTLLPLTLED
                     RKNKYLNGKLNVKVSIVLSKENPLMDVKLCVDNTIYNHRLRVHIKTDIKDNKNIASLP
                     FGYITRENGVLDNWEDIYSEMPIDLEPLESNITLTNQNRSCTIFTKGIKEYQHIEDEI
                     ALTLLATTDELGKPDLLYRPGRASGDTTKKGHIRIKTDKAQMLKKLEFSFAIYMDSKS
                     FDELEIANLTHNYLRECVNYQLQDYNFFLYRIDNKIQKSIVNKTVSRELEIISLPENY
                     LISACYPSYYSKDKFIIRVENPSSNKMILDEQIFKNRNGKIVNAIEDVEEEQVYEIAP
                     FDVISILLDL"
     gene            17613..17948
                     /locus_tag="ACGI5H_002461"
     CDS             17613..17948
                     /locus_tag="ACGI5H_002461"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004453818.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="winged helix-turn-helix transcriptional
                     regulator"
                     /protein_id="HFG9698161.1"
                     /translation="MYNIDDMIYNCPVEALSNILGKKWVAIIIWKIQEDKKRFGELQR
                     AIPDCSKKMLVQQLDFLIEQGIIVNQKKLVNNVVESTYFLSESGLRLLPVMEKMIMWS
                     NKNLNCDKY"
     gene            18085..19362
                     /locus_tag="ACGI5H_002462"
     CDS             18085..19362
                     /locus_tag="ACGI5H_002462"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891317.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0015036 - disulfide oxidoreductase
                     activity [Evidence IEA];
                     GO_process: GO:0017004 - cytochrome complex assembly
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cytochrome c biogenesis protein/redoxin"
                     /protein_id="HFG9698162.1"
                     /translation="MQNVNLFLVFIEGIVSFFSPCILPILPIYLSILSNSSVENLKEG
                     KTSFIGSSLFKNTIFFALGISTTFFILGSSVKVLSMFFNENKDLIMFIGGIIIIIMGL
                     FYMGIIKSSILNREKRFNVKFKEMKAITAFILGFTFSFGWTPCIGPILASVLVMVSSS
                     SNHLSANLLIAVYTIGFILPFIITAMFYSKLFKTIDKIKSNMEIIKKIGGIILIVSGI
                     LMMVNGFGSISKHFNTSQNSKIESKQEENKRENSTDKEENSDGNDSQKDSNNDNNDKG
                     SNDEDRIKSIDFTLTDQYGKTHKLSDYEGKVVFLNFWATWCPPCKEEMPYIEQLYKDY
                     NKNNDDVVILGVASPNLGREGSREHVVNFLKDQGYTFPVVLDEDGALAYQYGINAFPT
                     TFIIDKEGYVTQYIPGAMDKATMASFIENQRNK"
     gene            19483..20871
                     /locus_tag="ACGI5H_002463"
     CDS             19483..20871
                     /locus_tag="ACGI5H_002463"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422581.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-dependent oxidoreductase"
                     /protein_id="HFG9698163.1"
                     /translation="MKKTFDAIIIGFGKGGKTLAGDLANRGLKVALIEKSNKMYGGTC
                     VNVACIPTKSLENSANSVKTKNINSWDEVQAEYEKAIDKKETLITKLREANYNKLNSN
                     ENVTIFTGMGTFIDEKTVQVKTENEIYELVADNIFINTGSRPFIPNIKGIENKNIVYD
                     SESLMNLRTLPKKMTIIGAGFIGLEFAGIYSSFGAEVTILNSNNGILPNEDVEDSEEI
                     IKLLAKRNVKIVNNANIKEIKEVSELAIVEYEVDGKSKELTSNMILVATGRKANTEEL
                     GLENAGIELNERGFIKVSETLKTNKEHIWAIGDINGGPQFTYISLDDYRIVINQLFGD
                     KTRTTNDRKNIPNSIFISPAFSRVGLNVKQAKEKGYEVLVAKMPVEAIPRAKQIGKAD
                     GFIKIVIDKKSNKILGASMICENSSEIIHLIQLAVDLEVEYTYLRDRVYAHPTMTEAL
                     NDILSPNMIKEV"
     gene            21317..21955
                     /locus_tag="ACGI5H_002464"
     CDS             21317..21955
                     /locus_tag="ACGI5H_002464"
                     /inference="COORDINATES: protein motif:HMM:NF037435.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF434 domain-containing protein"
                     /protein_id="HFG9698164.1"
                     /translation="MKSKEEIEWLLNRDYKIDPVVTFVGDRYQFSIRQRDALKRAVCT
                     DEKNIIRQSKRLSLDKIKEDTVNIDGFNLIISIEVALSGGTLVIGSDGNIRDLAGLRG
                     TYKIIDKTEEALNLIGKFFNKYNAQNLKFYLDAPVSNSGNLKYRILEHAKTWGIETEV
                     ELVKNADVVLEKLDRVVSSDAVIVDKCISYFNVARGIIEEYIKECNIINLNK"
     gene            22073..22942
                     /locus_tag="ACGI5H_002465"
     CDS             22073..22942
                     /locus_tag="ACGI5H_002465"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422583.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SH3 domain-containing protein"
                     /protein_id="HFG9698165.1"
                     /translation="MRGWICVKLTKLNIKKYRAPIYKYALANVNLRSAKSTNSSIITV
                     IPQGAKMEVLDEEDDWIKVMYNSQEGYVYKDLVSVSEYAWSNLNLREDKSTTSNIITV
                     IPEKSRVEVLQVDGDWSKVVYDDKIGYVFNYFLSIDGNKPNELDYKYFYTDMIKFVNE
                     NNIKSTSDYLIVTDLRNKYTYIFKKDNGGWGQLYKWQCTIGKPETPTITGIFYISGRK
                     PSFGTDEYSVKYATRIKGGYYYHSVLYDSTGSYIIDGRLGEALSHGCIRLSTENAKWI
                     YDNIPDTTTVIIH"
     gene            complement(23097..24242)
                     /locus_tag="ACGI5H_002466"
     CDS             complement(23097..24242)
                     /locus_tag="ACGI5H_002466"
                     /EC_number="1.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903393.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016616 - oxidoreductase activity, acting
                     on the CH-OH group of donors, NAD or NADP as acceptor
                     [Evidence IEA];
                     GO_function: GO:0030554 - adenyl nucleotide binding
                     [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="iron-containing alcohol dehydrogenase"
                     /protein_id="HFG9698166.1"
                     /translation="MSIYYVPPINLLGKGCLNEAKDSIKSLGTKKAFIVSDKFLVSNG
                     TVKKVTDILSQIDVDFVVYDEVKQNPTVTNVNKGLKILKSENCDFVITIGGGSPQDCG
                     KAISILATNGGDIRDYEGINKTSKKCLPIIAITTTAGTSAEVTINYVITDEDRHVKMI
                     MVDTNSLATMTVNDPELMISKPSNLTAATGMDALTHAIEAVVANGAYDVTDSTALYAI
                     KQIFKYLPRAVKNGNDIEAREQMCYACFLNGIAFSNAGLGNVHAMAHQLGGLYDLPHG
                     VCNAMLLPIVEEENAKSAPAKFRPIAEVIGMDVNNKSDKECVDFVIDKIKALSEEVGI
                     PKSLKDVGVDNPNFELLAENSMKDACAGANPVFFDKDKIIELFMKIS"
     gene            complement(24575..25351)
                     /locus_tag="ACGI5H_002467"
     CDS             complement(24575..25351)
                     /locus_tag="ACGI5H_002467"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422585.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="IclR family transcriptional regulator"
                     /protein_id="HFG9698167.1"
                     /translation="MTSDNHRPTARILDILEALAESENGYTLTEIADVINAPKSSIFP
                     IVHTLNARKYITIDKNTSKYSIGIRSYTLGSSFFEKRTIFNYIIDEMTNIVNSCSETC
                     QLGILDNNEVLYIGKVDSPEPIRLISYVGKKIPANCTGLGKALLCDFDKEKLISLYPD
                     GLKGFTEKSITDFDVLYDQLLEVQRTQIASECEESMEHLKCLAVPIRKNGCIRAAVSV
                     TLPLFRANDEKIELIKKLLLNAQKNIQSMMEERNEDIVIN"
BASE COUNT        10117 a         2709 c         4335 g         8483 t
ORIGIN      
        1 ttatattaat aaactttaat ataatatatt tatgaaaaat gtaaactgtg aaatggaggt
       61 agtaacatga aaattgaaaa tctttctatt gatgatatta aacgaggcta tatatttaat
      121 gatgatttaa attgttatag ttgcattaaa tgtacaaaaa catatgaggt aggagaaata
      181 tataaaatag gtaatagatt ctttgaagct tcaaaagcta ttgaacttca tatggaatta
      241 gaacatagtg attatttaga gcaattgctt aatagtgatt caaaatacaa cacattgact
      301 gaaaatcaaa aacaattatt tcaattattt attagtgatt taccagataa ggagatagca
      361 aaacaggttg gagtatccac atctactata cgccatcaaa aatttatttt cagagaaaaa
      421 gcaaaacagg ctaagctcta tttagcacta tatgaatctg tatttgaaga taaatctaat
      481 aaaagtagta ctataatacc aatccatgaa catgctcgaa tggtagatga aagatatgta
      541 gtaactgaag aagagagaaa acacattttg gatacatcat ttgaaagtat gaatccttta
      601 aaattaaaag tattttcttc aaaagaaaag aaaaaggtcg taattttatc taagattttg
      661 gaacaatttg aacgtgggaa gaaatattca gaaaaggaag ttaatcagat tttagaatct
      721 atatatgatg attttgcaac aattagaaga tatctaattg agtatggttt tatgagtaga
      781 aataaagaat gtacaaaata ttggttaaca taattaaaat aataaatttt actaatgtgt
      841 aatgttattt ttatctaggg ggaggagtca aatatgaatg atgaattaaa atctatttta
      901 tacaataaag gtgtggacat tgttcgcttt gttgatatat ctgaatttcc aataaatcaa
      961 acgcaaggtt tttctaaagc aattttattt tgtatagggt tatcaaaaaa atttattaca
     1021 gatatataca ataacttacc tacagatagt gatgagtttt tagaaaaaga ggagaaagca
     1081 gaagaattag ctgactggat ttcagaatat attcaaaata aaggatatag agcgtattct
     1141 caatcggaga aaaacaatct agaacatgga tattttgaaa aagcctatat taatccagaa
     1201 atgcaatcag ggattagtcc tttaccacat aagacaatag caaatattag tggcattgga
     1261 tttatgggaa aaaataattt gtttgtaaca gaggaatacg gatgtgcttt tagcatgtgt
     1321 acagtactta cagatgctcc aatttctgtt gaaagatatc ctttgattga ttcaaaatgt
     1381 atggattgta atgtttgtgt agaaaactgc cctgcaaaag ctatacatgg aaatgagtgg
     1441 actttgccag gaaaaagaga gtctattatt gatgtttcaa agtgtttttg tgtattgaag
     1501 tgtatgatga gttgcccatg gtcattaaga tatgcaaatc aaaaataatt ttactagaga
     1561 aggtattaaa ttgaatatta taaaattttt aaaatgtaag attatataag atttttcaaa
     1621 ataaaaattt gtatagaaca ctcagaaatg agtgtttttt tattggaatt aaattatatt
     1681 gatacaaagt ttaactattt taatcattat ataaaatttg tattaaaaaa ttaagaataa
     1741 cttggtaata gtgaaaatat aatgagatta taattgattt ataatataac tataatgatg
     1801 ttgtaaaatg aaaattgtca tttcaaaatt cccaaaaaga gtaaaagtca cttcggttat
     1861 agtcaaaaaa ttttttcagt gaaaagaatt tagatttaaa agggaggaat taatcatgga
     1921 aattgaaact aaaactccgg attggattaa tgtactagaa ttaaacagta aaatagatat
     1981 tactgggaaa tatgatgtaa gtaatattat acaagatatt gtctctgata agtcactaga
     2041 aggttccatt atatattttc caaaaggtaa ttatttattt gagaaaggta ttaaaattag
     2101 tcaacaaata acacttcaag gagattctta ttatggagga gataatcaag tatcaaattt
     2161 agataaaaaa caatcaatca taggaacaac caattttata actcgaggag tttctaatat
     2221 gagtattatt gcattgacag gaacaagtca atgtatcaaa aatattaatt tttattatga
     2281 tagtcatgat atagagaaaa taccgcctaa aaatgtatct gctattacag aatatggaga
     2341 aacacaagga ctatctcatt ttgaacacct gtttatttct ggattttcag ggatagggat
     2401 tgaaattcca tactattcaa ctggcaatga tataattgtt agttcatgtg gtcttggtat
     2461 gaggcttgga gagaagtcaa tgctttctag tagcaagatt tacgaatgta aaaatggaat
     2521 ggagattact actggtgtta gcttaaataa tgtgagaata gaagaaataa aagaaatagg
     2581 tattaataat aaaggatttg gttttaacct gattatgaat cttatggtcg accaatgtgg
     2641 atattgtgga tttatgtttg aaaaaatgtg ctatagccag ataactgcca gaattactag
     2701 atgcggtcag tattataaaa gtgttgatta taatgcttat gagaatatgg aagatagaaa
     2761 agaaaaagct tattccattt tttatggaga tattttagaa agttgcaata ttgtattgat
     2821 gaatagaaat attgatacct tagaaagtga ttcacttaat gaacataaga tatatgtaat
     2881 caaggcaaat gaaacaaaca atgtaatgct aacatgttat gctgaagcag ataactttat
     2941 acaatgtgca aagggcaact tgctgttaga aaatggtgaa aatacttata aattttataa
     3001 tggtgagatt tgttctgtag gaggtgttca aatttctgat atagatgaaa aagatttaat
     3061 caaaataata gagaacactt tgtatataga tgataaaggt aagtatttaa tggttcctag
     3121 attaaaaaag aatactgtaa tatattcagt actagattct acagaagaaa taaataaatt
     3181 acatggtgga atatgggaac agattgatgt aaaagtatta gctggggaat ccatgtacta
     3241 ttataaaaag ataaaagatt aaattatcaa actaggaggt agtgattaat ggaagagtct
     3301 ataataatta aagatataag tggctggatt aatgtacttg attatggaat ttgtaatgat
     3361 gaaacaaaag atgtaagttt taagttgcaa gagattatgg atgctgtacc agaagattct
     3421 attatatatt ttccaaaagg aaaatactta tttgaaagtg gtgttaagat taagaaacga
     3481 ttaaccttat gtggagattc ttatatttta gcgaatgttc ctaaaaatac tgctggagta
     3541 acacagttta cttttaaagg aaagaaaaat cctaaaagtg aaaatagagc aatcataaca
     3601 gcaaaaagtg taagacactg tattaagaac atttgctttt attcagatag ttgtgataga
     3661 gatatgacat ctaatcatga acctccaaca gatggaaaac ctagatttca tcataatgta
     3721 attataaatt atagaaatat atctgctgtt atatgtgaag ataaacaggg agaaccaggt
     3781 cattatgaaa atctatcttt tagtggtttt tctggaattg cacttgatat gcctaataat
     3841 tctacagcaa atgatattac aatttttaca tccggacttg gaattagtac aggggaaaat
     3901 tcaacaattg ctaacagtaa ggtttggggc tgtgttgatg gaatgataat ttctactgga
     3961 acttttataa atggtatgag ggtagaagaa ataaaaaaag ttggaattaa aaatattggt
     4021 agaggtttaa attttattac aaatatcaca attgaccaat gtggatattg tggagtttgg
     4081 tttgattcta tatccaatgt tcagatatca ggaaatatca caaggtgtgg gcagtactat
     4141 tatgatgtaa gctatgataa ttatttaatg ttggataata gagttaaaga agcatattct
     4201 ttattctatg gtaatttatt ggagtcaagt aatatagttt tatcaaatac caatgaagat
     4261 aattgggaag atttcaaaga agataagcat aaggtgtatc ttatagaagc acttaaaacc
     4321 aagaatgtac tattaacatg caatatagat gctactgact ggattgttaa gtcagaaaaa
     4381 ggaaatttaa cgtacaataa tatgcgacaa actgttatat tttacgatgg aaaactaagt
     4441 agtatcaatg gaattggtat atctgatgaa gattatgggg ataaagtcaa gataaaaaaa
     4501 ggaaatatat atataaatag taatgataag gatattaaga tgcataaacc agaggtaggt
     4561 gacattatgt caacaattat taaagataaa agtattcttt ctgctcatta tgggggaaca
     4621 tgggagaaaa ttggtgaaaa aatagagttt ggaataactg tacactatta taaattgata
     4681 gagaaataag taaatacgta gtatttgaat agatgtattt tattggagag ttaggactat
     4741 agttttaata taaatggttt ggtaatagca tggattgaat aatataaaaa taatataaaa
     4801 aattaatttg attatgtaaa tttctatgaa gtagtaaaac tgtgacttta gtcataggag
     4861 gttcaaacta agtaaaaggg aaaggaatat ataatattat ggaaggaaga actgggatta
     4921 aagatggaag atggattaat gtagtagaaa gaggtattaa aaatgatggt tcgtacaaca
     4981 taggtcctgc tttgcaggat attattgatg aaatagaaac agatttttgt gtcttatatt
     5041 ttccaaaagg taaataccta tttacaagtg gtgttaaaat taataaagaa attgtattgc
     5101 aaggtgattc taattcatct acaggtacta cacaatttat aactcgtgga gtagaaaata
     5161 tgagtattat tacattgaca gggaagaaac aatgtattaa aaatataaat ttctattctg
     5221 atagttgtga gatacaggta aataaagaac caccgacaaa aggtaatcct aaatatcatt
     5281 atgagatgat tattaataag aatgaaaaga atgttgagat gaataatgta tcagcaatcc
     5341 tgtatgataa cagtaagaat atgattaaag gtctaggtca ttatgaaaat atttatataa
     5401 gtggtttttc gggtacagga attaggatac catattactc aattgtaaat gatattacag
     5461 tttcatcttg tgggctgggt attgatacag gaatagacac aattatttct aatagtagaa
     5521 tatctaagtg tcaaaatgga atgaggatta gaactggaac tagtataaat aatgtaagga
     5581 ttgaaaaaat acagaaagtt ggtcttataa gtagtcaagt taaggggtat gaggggtatg
     5641 gaagttataa aattaataat attacgattg accaatgtgg gtattgtggc ttttcatttg
     5701 attcaatgaa agatagttat ttttctggta ttataagaag gtgtggtcag tattattata
     5761 atacagatta tgacacatat ttaagtatta aagatagagt agaagaagca tattctttat
     5821 tttatggaaa ttattttaca gaatgtaata ttgatttagt tagtgataat aaggataact
     5881 gggatgatgg cttagaatat aaacataaag tttatgtatt taaaaccctt caaataccaa
     5941 aattaacatt gagatgcaat atagatgcct atgattatat cgttaaatcg gtacatggag
     6001 gaggtaattt aatgttaaaa aataacttta acaattatat atttattgat tcatctaatc
     6061 cagaagttat taatggaatt aattttaatt atcaaaagaa tggaaacttg ttaaggttaa
     6121 ataatggtaa attaagttat aaaaatggaa aggaagaaac agctatattc agacctaatt
     6181 atggtcttat tgtagcatca acagattcag aatgtgaaca aatagaggct acctatggag
     6241 aaaaatggga gaagcttggt tctgaagtaa ttggagaaga aacggtatat tattataaac
     6301 atcatgaacc agataaaaca aaccaaatac aataaaattt gtattatata atgatataaa
     6361 gttttaatat atagtgttta cctttaatgt aatattggta tatttgtata gtattaaatt
     6421 tgttaaaaag taaaattgta gggtgcttga aaatagcacc ttttttagtt tcattataaa
     6481 attagttttg aaagtttagg aataatgtat atttattttt aaagaattat aaccttatta
     6541 aggatatttt aaatgctaga aatgaatcag taaatcatac tggaattatc ttaaatgttt
     6601 tgattaaatt aagtatttag agctataatt atattaaaaa tatattagaa cataattata
     6661 ttactatgga ggttaaatat gatagtaagt gtgagtagaa gaactgatat acctgctttc
     6721 tatagtaagt ggttttttaa cagacttgaa gaaggttttg tttatgtaat taatccaatg
     6781 aatccaaaac aggttagtaa gatagagtta aatccacata ctgttgattg ttttgtattt
     6841 tggacaaagg atgtaactcc aatgttatat gatttaaata aattaagaga ctataaatat
     6901 tattttcact atactataac atcatatgga aaagaagtag agacatgtat tttagataaa
     6961 agaaaggtaa tagattcatt taaggaattg tctagaaaaa taggcaaaga aagagtaatt
     7021 ttaagatacg acccgatttt cttaagtgaa aagtacacag tagattatca tatcaaagca
     7081 tttgcgagtt tatgtaatca gcttgatgga tttacagaaa aatgtataat aagttttatc
     7141 gatttgtata agaaaacaaa atttaatact aaagcattac atataaagcc aatagaaatt
     7201 acagaaatag aaacattatc aaaagagatt tctaagattg ctcataagca tgggataata
     7261 cttgaaatgt gttctgaaga atataattta agtaaatttg ggattggaaa aagtaagtgt
     7321 attgatgata gattaatatc aaaaattata ggatgtgaag tagaggtaaa aaaagatagt
     7381 acacaaagag atatttgtgg atgtgttaaa agtgtcgata taggacaata caatacttgc
     7441 agacattatt gtctgtattg ttatgctaac tttaattatg caaaagtaga agaaaactgt
     7501 aggctttata aggaagataa taaattactc atagatactt taagagatga tgcaaaaata
     7561 agcattagag atatgaagac tattaaagta gataagaata aacaaattag tatatttgat
     7621 taaaataaat atactaatta ccttaatata ttaagaatat agatactttt gataacaaaa
     7681 ttaaacttaa tagatatttt ctatataaga aagatggtca taatatgtca atttgaccat
     7741 ctttttgata taattaaaac acaaataatt tagtaacaaa ggaggcagaa cttgaattta
     7801 ttaaaaaaat atcctatacc tattgcaagt ttgattttat caatttttac tttaggtaac
     7861 ttattacaat cttatagtga atcattacgt aatgtaattg gatttatagg atttattttg
     7921 tatgcaattt atatagtcaa aataatatta cttagaaagg gtgttaaaga gcaattagag
     7981 aaccctttaa tatcaagtac atttccaact ataacaatgg caacaatgat atttgctaca
     8041 tatataaaac cattatcttt agaattaagt attatgattt ggagcatagg aattgtgggt
     8101 catcttgtgt taatagtctt atttagtaag aagttcttag ttaaattctc aataaaaacg
     8161 gtatttccat cttggtatat agtatatgtt gggatagttg cagctagtgt tacggcacca
     8221 gcatttaatc aacttttgat tggcaaaatt gccttttgga taggatttgt atcttatata
     8281 gttcttatac cagtaatttt aaagagagta tggataatca aggaaatgcc tgaaccatcc
     8341 ttaccaagta tagctatatt agctgcacca gggtcactat tattgtctgg atatattaat
     8401 tctttttcag ataaaaataa tgtagtatta tacttgttat tcatattatc aattgtattt
     8461 tatattatag ttttgggata tttaccgaaa ttattaaggt tgccttttta tccgagtttt
     8521 gctgcattta cattccctat ggcaataagt gcaatgggta tgaaactaat gaatggttat
     8581 ttaactaaat caggtcattt tataagttgg atttcatatg cttctaagtt agaagagata
     8641 attgctacag tgattatttt atatgtttta gttttgttta ttatatatct tagtaaatct
     8701 gaaactacat ctaaagctaa ataagaatta ttaaatatgt gtatttaata ggaatattga
     8761 tataaatata tgaagataag ataaaccata gaaacttaat ttagcttaat tttattggag
     8821 gaaaacaaat gaaaacaaaa gaagaatatt taaaagaagt tagaaacata tcagaagaat
     8881 actttagaaa aggagagttt ttttgctctg aagcagttct ccagacaata aatgatgctt
     8941 taggccaacc tttaagtcca gagataacta agttagcatc aggatttccg ataggacttg
     9001 gaaaggcaca atgtctttgt ggagcaatat ctgggggaga gatggcttta ggtatagtat
     9061 atggaagagt tcatggtgaa gctatgaatc caaagatgtt tgagcatgct aaaggtttgc
     9121 atgattatat taaaaaagag tatggtgcaa catgttgtag agctattaca aagaaatggg
     9181 atggtgataa ctttatgtct cccgaaagaa aagagcactg tattaaaata acaggtcaag
     9241 ttacagagtg ggttgcagat aagcttatag aagatgaaaa acttaatatc aaatagtgta
     9301 atattagttg gtgaatttat aaagttaaat ttacttatag tataagatac ttgatattct
     9361 cgtattgata gaaaaattta tagcatatgt atttaatgaa atatacttat atttagagtg
     9421 tggtttaatt tcataaatac atatgctatt attttaagta tataagcaaa tttatttaaa
     9481 taaatagaaa cagttaattt atatgtacaa aactatatat gattagtgta aataaatacc
     9541 tattttataa tactcaacat aaagacacca gacatgatta gtattatacc aataaaaata
     9601 gcaagccatt cttttttgtt cttcttttct ttaaaaaata taatccctcc taaagtggct
     9661 actatcacac aactctgaga gatagaaaaa cttattgtaa ctcccaatgt attagtcgtt
     9721 atgaacatac ctaaatttgc tattgaccac aatataccag taattaaatt gaataaaaca
     9781 ttttccctat atacaatctc tttagaaaaa tacttgacaa taatagatga agttatcaac
     9841 ataccaacag attgaggtaa tataattcta tatccttcaa ttaaaaatat ttgattagtt
     9901 acaacatata atgataaaaa tagagatgat aataatacaa ctccaacaca ttttaacata
     9961 tttttatctg tagatttttt agtttgataa tttgtgagaa gtataccaag tattatacat
    10021 aatattgata aagaaccaat cagtaacatt ttagaactgg tccattcatt aaacaagatt
    10081 acagctaata atgtcgtaaa agttaattgt gaaccatttg aaattggcat tactttagat
    10141 acactagcaa tttgaattgc tttaaactgc attaattgtc ccaaactcca gaatatgcca
    10201 gaaatcatac ttatacaaaa tgaaaaaaat gtaatttcag gatgtataac cagagttatt
    10261 atagtggaaa atataaacgc acttatggat gtacctaaaa gctgttcatg aggagaactt
    10321 ttctttagat ttgcaactat gggcatcaat ccccatccca ttacaggaag taaagcaata
    10381 attattgtca gcattaaact atttcctttc atattaaatt tagacagctt ttaatttatc
    10441 atctaaaatt aaagtgttca atacataaaa attaccgtat ttaatcagga aatattagta
    10501 gttttttaga aaaacatttt ccattaaaat aaagacaaag ggaaggagta aaattgaaaa
    10561 tgttaactga tatgattcaa aatcgtgaaa ttaaaataat aaagttttta ttaaaagaag
    10621 gtcatacaac tgtaaaagca atagcagatg atttagatgt ttcagaaaaa acagtttcaa
    10681 aatctcttaa agaagtagaa gcagtgctta aaaagatagg tctttcttta ataagaaaac
    10741 ctaagatagg tgtttatatt gatggagatt taaaaaaaat acttccttac ctagataata
    10801 aaggaagtca aattcctaca accagagagg agagagttat ctatatatat tcagtacttt
    10861 taaagagtaa tgattatatt actatacaac aactttctga tgaactatat ataagtcgtg
    10921 gaactattga aagggattta gcagaagttg aaaaactgct aaaaaacgaa gggatttcca
    10981 tatataagaa acctagtaag ggaataaagt taaatataag tgaaagagat aaaagacaac
    11041 ttactgctaa gtttatacat aaattttgga gtagaaactg gtatattaag caagagcaag
    11101 aaagctttta tcaagcattt gaaaagatac aagcagatgt aaatggtatt ttttcggaag
    11161 atgatttatc aataattatt gatattctta ggaatttcag cagagaaaga aaatttgagt
    11221 tctctgatta tgaatttcag tcattagtta ttcatttggc aatagctgta gagagaatta
    11281 gaaaaggcga atatatagaa gaaagtttgt atactggtaa tatagaaaat aatcaaatgt
    11341 caaataccaa ttatttagca aaacaattag aagaaaaatt ttcaatatta ttaccaaaat
    11401 ctgaaattgg atatataaat ttacatttag tagcgtctga ccaacataga gatactaatg
    11461 aactaaaaaa tacttcaact aatccttgtg agacaagtac aaataatata tcaaatcttc
    11521 gggaaattat aaaaaataca ttgtatgaga cagcttatga caaggattta attgatggat
    11581 taacttcaca tgtacattca tcaataaata gactgaaata tggacttagt attaaaaatc
    11641 catatgtaaa tacaatcaaa caaaactttt ctttatcatt tgagcaagct ttagatttaa
    11701 agaaagtaat tgaatttata tatgatatta ggataaatga tgatgaatgt gcttatatag
    11761 cattacattt tgaagctttt agagaaagaa tgaaagaact tccacaaaat attagagtaa
    11821 ttctagtatg cagtacagga ttaggttcat ctaggttatt gtctgcaaga ataaaaaaat
    11881 actttccaat gataaagatt gaaaaagtac tttccgtaca agaattagta tccagtaaaa
    11941 ttgatgcaga tttagtaata agtactattt atttagagtt agaaacaatt ccaaccatag
    12001 tagttagtcc tattttaaat gaaagtgata taagaacctt ggaaagaaat atacaaaatg
    12061 tttcaagtta tacttctaag aagtataaat ctttcagaaa cttaatcttt gaagaaaata
    12121 tattgttgaa tattgaagct tcaaactatg aagatgcaat taagtatata acagataacc
    12181 taataaaaaa aggttttgca aaagaaggta tagctaaaag tgcaattgag agagaaaatt
    12241 tatcttacac ttctttccaa tcaatagcta cacctcatgc taatcctagt tatattaaaa
    12301 aatctaatat atctgttgca acgttaaaaa atcctattac atggggaaat gaaaaggtgg
    12361 aagttatttt ctttatttca ttagaaaatg acaaaaacct agagcttgat gaaatatatg
    12421 aagtttttta tgacttcatt gacaataaaa aaaatataaa tgacatatta agtgcaactt
    12481 ccacaaagga agtgtacgat ttgctagtgg aggagagtat atagtgaaaa tatcagatgt
    12541 attgaaaaaa gagcaaattg tttttaatct tgatacaaat acaaaggaag aaacaataaa
    12601 aaaattaagt agtatatttg ttgaaaatgg gattgtggac aatgaagaag aatatgttaa
    12661 gtctgttttg gaaagagaag aacattcaac tacaggtatt ggtaatggta ttgctattcc
    12721 tcatgggaaa agtaatgctg tcaaaaaatc ttctataata tttgcaaaga ctaagcataa
    12781 gattgaatgg gatgctttag atgaaaaacc agtagatagt attttcttat tggctataag
    12841 caatattgat aaggatagca atcatcttgt actattatct aaattagcaa ctaaacttat
    12901 ggatgatgac aatgtagatg cactaaaatt agccaattca gaacaagaaa taatcaatat
    12961 atttagtgaa gaaggagaga tgtagaaatg aaaagaaaaa ttatagcagt tacagcatgt
    13021 gcaacaggag ttgcacatac atatatggca gctcaagcgt taaagaaagc ttcaaaaaag
    13081 atgggtcacc ttataaaagt tgaaacacaa ggagctacag gaatcgataa tgagttaact
    13141 acaaaggatg cacaaattgc agaagtagta atatttgcag tagatactaa agtcagaaat
    13201 gctgaacgtt ttgagggaaa agaaatacta gaagtaccag ttaatgcacc tataaaggat
    13261 gcagagaaag taataaatga tgcactaaag ttaattgaca ctaaataaat ggagggaaat
    13321 gtaatgttga aaaagatagt ctctgagtta aaaaagcatg tcttaactgg aatctcatat
    13381 atgattccat tagtaattgc aggtgctatg ataatggcga tatctcgtgt aggtggttct
    13441 ttctataata taccagatat atgggatgct aaatatgcag aaagtgctag tagtattgtt
    13501 agattattac atgatttaga tgggtttgga ggtactgcat taggattaat gtttcctgta
    13561 attgctgcat ttataggatt ttctatagct gataaattag ctattgtacc aggtcttgtt
    13621 ggaggtatga ttgctaaaga tataggtgca ggatttttag gagctttggc agttggtctt
    13681 atagcaggat atacatgttt gtttattaaa aatcatgtta aattaccaaa atcagcagct
    13741 tcaatagtac caatatttat agtaccagta tttgggacat taatcactgt tgtattaatc
    13801 aattatgtga taggtatacc ttttgccaca ttaaatactg gattagaaaa ttggttaaat
    13861 ggattatctg gtacaaatca gatactaatg gcagctatta taggggctat gatggcagtt
    13921 gacttaggtg gaccagttaa taaagcagct ttaacaacat cacttgcatt attaacaagt
    13981 ggaatttatg cgcctaacac tgctgcaatg gtaggaatag ttataccacc actaggattg
    14041 ggacttgcta ctatactagc aaaacaaaaa tataataaac agttacgtga agctggaaaa
    14101 tcatctctta taatgggttt aattggagta agtgaaggag caattccttt tgcggtagaa
    14161 tctccattaa aagtaatacc ttcatgtgta attggaacag caattgcttc agctatggca
    14221 gttggtttag gttcagtaaa tgcaactcca attagtggat tttatggatg gtttacagta
    14281 gagaattggc caatgtatgt gttatcaata gcagttggaa cagtaattgt agctggatta
    14341 gttatagtat tgcgtggaaa tccagtgatt gaggatgatg aatttgaaga tgatgatttt
    14401 gatgaagcag agtgggaatc ttaaaattta ataactattt aagacgtgtt ataagctata
    14461 ttcaatatga atcttatact aaataaagtg ttaaacattc agtttagact taaatataaa
    14521 agataaagaa cagaggagaa taaatgataa aagcacatat tgttaatcat acacactggg
    14581 atagagaatg gtattttact tctggagatg cattagtact tagtgaacaa ctatttacag
    14641 atgtaattga tgaattagaa cgtaatccag atgtaagttt tgtacttgat ggacaacttt
    14701 ctattttgga tgattatgta caattacaca aagaaaaaat agaaatcatt aaaaagttaa
    14761 taaaagaaga tagactacat attggaccat ggtttactca aactgatgca ttctttgcta
    14821 gaggagagtc tattttaaga aacttaatga ttggaatttt tgaaagtaaa aagtatggta
    14881 agtatatgaa aattgggtat ttgccagata catttggatt taatgcacag atgcctatac
    14941 tattaaagca tgtaggtctt gataatatat tcttttggag aggtatacat cttggtaaac
    15001 aggttcaatc accatatttt aagtggaaaa gcttaaatgg agaaagttat atatatgcag
    15061 taaatatgcc acatggatat ggaactggta tgcttttaga gccttcatta aagtatgtta
    15121 atggacgctt agacccagct attgatttta ttaaatcata tactgatgta gatgaggtgt
    15181 taataccttc tgggaatgac cagttaaata taataggtga tttcaaaaat aaaattaaag
    15241 cgattaatga tatcggaaag tattcatata taacgagttc atatcaagag tttttaaaat
    15301 atataaagtc catagaatca ctagaaagct atagaggaga atttagagaa cctgtattag
    15361 caagaataca taaatcaatt ggttctagta gaatggatat aaaattagca tgtgataaac
    15421 tagaaaacaa gctgattaaa agaatagagc cattattagt aattgctaaa aagagtaaaa
    15481 ttgaaataag caatcagtta cttataaata catggaaaaa acttttggaa ggacaagcac
    15541 acgatagttt agctggatgt gtaactgata ctgtaacaga tgatattctt caccgtataa
    15601 gagaagcaaa tgaaatatgt gacagtattg aaaatactat tgtaaaaaag atttcagaag
    15661 ggcttaaatt atctaaaaat gatattttag tatttaatac agaagctaag cgttttaatg
    15721 gatataaaga gatacaagtt gtaagtgata gtaaaaatat ttattttaaa gataatttag
    15781 atgctactat aattgaagaa acttatgtaa aaccgagaga aaatgtatta gaagaaacac
    15841 ctgctggtaa tatatttatt gaagaaccag gatattatat attaaaagta agaataaatg
    15901 tacagcttcc tgcacttggt tataaagttg ttagttttga atcaagtgat aaagaaatgg
    15961 tgtcacttaa taaatctaat gatgctttta tatctaatga taattataag ataatatatg
    16021 aagatggaag cttaaattta caacttaaag atggaactta catatcaaac tttttaacat
    16081 taaaagatag tggtaatgca ggtgatacct atgacttttc tccactaaaa aatgatgagg
    16141 atataaaact ttcgtttgat aaagtgtata cagaaaaagc tttaggatat gaaaaaatgg
    16201 tggttaaagg tactacttta ctaccactta cgttagaaga tagaaaaaac aaatatctta
    16261 atgggaaatt aaatgtaaaa gtaagtattg tcttatccaa agaaaatcca ttgatggatg
    16321 taaaactttg tgttgataat acgatatata atcatagact acgtgttcat ataaaaactg
    16381 atataaaaga taataaaaac atagcatcat tgccatttgg atatataaca agagaaaatg
    16441 gagttttaga caactgggaa gatatttaca gtgaaatgcc tatagattta gaacctttgg
    16501 aaagtaatat tactctaaca aaccaaaata gaagctgtac tatatttact aaaggaataa
    16561 aagagtatca acatattgaa gatgaaattg cattgacctt acttgctact acagatgaac
    16621 taggaaagcc tgatttatta tatagaccag gacgtgcttc tggtgataca actaaaaaag
    16681 gtcacataag aattaaaaca gataaagctc aaatgcttaa gaaattagaa ttttcatttg
    16741 caatatatat ggattctaaa tcatttgatg aattggaaat tgcgaattta acccacaatt
    16801 atctaaggga atgtgtaaat tatcaattac aggattacaa tttcttttta tatcgtatag
    16861 ataataagat tcaaaaatca attgtcaata aaactgtaag tagagaatta gaaataatat
    16921 ctttaccaga aaactatctt atatcagcat gttatccttc ttattacagt aaagataaat
    16981 ttataataag agtggaaaat ccaagtagta ataaaatgat attggatgag caaatattta
    17041 aaaatagaaa tgggaaaatt gtaaatgcaa tagaagatgt agaagaggaa caggtatatg
    17101 aaatagcacc ttttgacgtt atttcaatat tattggattt ataagtgtaa aagtaagttt
    17161 attgtttaaa gtctgacaga tattaatctg ccagactttt taatttgtat aaatttgggt
    17221 aaatattaat gaatggtttt agtatttaag tatgaattta gtatttaata tagaatttat
    17281 tgaagtagaa taattagttt aacaggataa gcagtttaaa taaagaatta ttatattaga
    17341 gtgattttat atataattta agataataaa attttaataa aatgagttaa agattgtata
    17401 ttaatagagt tgatgtagtt acaaaaaagt taccaattgt tatgtattta caaaactgat
    17461 atattaatta cataaaatct aaaatagttt gtaataggag tatatataat aaaaatttta
    17521 attaaataaa gctaggtata tttataatat taataaatat attgctataa aagtttgttt
    17581 aataaattaa ataaagaaaa gaggagaata aaatgtacaa catagatgat atgatatata
    17641 attgtccagt agaagcttta tcaaatattt taggtaaaaa atgggtggct ataattatat
    17701 ggaaaataca agaagataaa aaacgatttg gagagctaca aagagctata ccagactgta
    17761 gtaagaaaat gttagttcaa caactagatt ttttaattga acaggggatt atagtcaacc
    17821 aaaaaaagtt ggttaataat gttgtagagt caacatattt tttaagtgaa tcaggattac
    17881 gattgcttcc tgtcatggaa aaaatgatta tgtggagcaa taaaaattta aattgtgata
    17941 aatactaaaa tttactctgt aagtaatgaa aatttaatta agctatgagt agaaaaatgt
    18001 attaaaatta cataattttt tagttagatt ttaatttaga aatgggattg taatattgga
    18061 aataaaataa ggaggaattt taatttgcaa aatgtaaatt tatttttagt atttatagaa
    18121 ggtatagtat cattcttttc accatgtata ctgccaattt tgcctattta tttgagtata
    18181 ttgtcaaata gtagtgtaga aaatttaaaa gaaggaaaga cgagttttat aggaagttct
    18241 ttatttaaaa atactatatt ttttgctctt ggaatctcaa caacattctt tatattgggt
    18301 tcatcagtaa aagtattgag tatgtttttt aatgaaaata aagatttaat aatgtttatt
    18361 ggtgggatta taattattat catgggatta ttttacatgg gaataattaa atcttcaata
    18421 ttgaatagag aaaaaagatt taatgttaag tttaaagaaa tgaaagcaat aacagctttt
    18481 atattaggtt ttacatttag ttttggatgg acaccttgta ttggtccaat attggcatct
    18541 gtattagtca tggtttcaag ttcaagtaat catcttagtg cgaatctttt aatagcagta
    18601 tatactattg gttttatttt gccattcata attacagcta tgttttacag taaactattt
    18661 aaaactatag ataagataaa atctaacatg gaaattatta aaaaaatagg tgggattata
    18721 cttatagtat caggaatatt aatgatggta aatggatttg gaagtataag caaacacttt
    18781 aatacgtcac aaaatagtaa aattgaaagc aagcaagaag aaaataagcg agaaaattct
    18841 actgataaag aagaaaattc tgatggtaat gatagtcaaa aagactctaa taatgacaat
    18901 aatgataaag ggtctaatga tgaagataga ataaagtcta ttgattttac tttaacagac
    18961 cagtatggta aaacacataa attaagtgat tatgaaggca aagttgtatt cttaaatttt
    19021 tgggctacat ggtgtcctcc atgtaaagaa gaaatgcctt atatagaaca actgtataaa
    19081 gactataata aaaataatga tgatgtagta attttaggag tagcttcacc taatttaggt
    19141 agagaaggtt caagggaaca tgtagttaac ttcttaaaag accaaggtta tacattccct
    19201 gttgtacttg atgaagatgg agcattagca tatcaatatg gaattaatgc ttttccaact
    19261 acatttataa ttgacaagga aggatatgta actcagtata ttccaggagc tatggataag
    19321 gcaactatgg catcatttat tgaaaatcag agaaataaat aaaagtattt aagtataagt
    19381 ttataaatca atttaaggtt acaaaaaagt gcctaattgt accacctaaa taatcttgtt
    19441 atagtaaaag tataaacaat acaagaaagg gttgaatttt atatgaaaaa aacatttgat
    19501 gctataataa taggatttgg aaaaggtgga aaaacattag caggggattt ggcaaacagg
    19561 ggattaaaag tagctttaat agaaaagtca aacaagatgt atggtggaac atgtgtaaat
    19621 gtggcatgta taccaacaaa aagcttagaa aattcagcaa acagcgtaaa aacaaagaat
    19681 ataaattctt gggatgaagt acaagctgaa tatgagaaag ctatagataa aaaagaaact
    19741 ttaattacaa aactcagaga agctaactat aataaattaa attcaaatga gaatgtaact
    19801 atattcacag gaatgggaac tttcattgat gaaaaaacag ttcaagtcaa aactgaaaat
    19861 gaaatttatg agttagtagc agataatata tttattaata ctggttcaag accatttata
    19921 cctaatatta agggaattga aaataagaat atagtatatg atagtgagtc tcttatgaat
    19981 ctaagaactt tacctaaaaa aatgacaatt ataggagctg gatttatagg tttagaattt
    20041 gctggtattt atagttcatt tggagcagaa gttacaatat taaactctaa taatggcatt
    20101 ttaccaaatg aagatgttga ggattcagaa gaaataataa aattacttgc aaagagaaat
    20161 gtaaaaattg ttaataatgc aaatataaaa gagattaaag aagtttctga attagcaata
    20221 gtagaatatg aagtagatgg taaatctaaa gaattaacaa gtaatatgat acttgtagct
    20281 acaggaagaa aagcaaatac tgaggagcta gggctagaaa atgcaggtat agaattaaat
    20341 gaaagaggat ttattaaagt ctcagaaact cttaagacta ataaagagca tatatgggct
    20401 ataggagata taaatggagg tccacaattt acttatatct cattggatga ttatcgcata
    20461 gttattaatc agttgtttgg agataagact agaacaacta atgatagaaa gaatatccca
    20521 aattctatat ttataagtcc agcattttca agagttggtc ttaatgttaa acaagctaaa
    20581 gaaaagggat atgaagtatt agtggcaaag atgccagtag aagcaattcc aagagctaaa
    20641 cagattggca aggcagatgg gtttataaaa atagtgatag ataaaaaatc caataagata
    20701 cttggagcta gtatgatatg tgaaaattca agtgagatta tccatcttat tcaattagct
    20761 gtagatttag aagtagagta tacatattta agagaccgtg tttatgcaca tccaactatg
    20821 acagaagctc ttaatgatat tctatctcct aatatgataa aagaagtata acataagttt
    20881 aatatataaa cctaaaatta tcattataag tagattttag aaagaggcta tctcaaaaaa
    20941 tagagataag tctctttttt actgtttaaa tgataaaaat atatttgatt ttataaaaga
    21001 agattatctt atgaactaaa aagtttattt taaaacacta cctatttatg ttataaactt
    21061 ataaatataa tatagaatct attattctgt attattaagt ggggttaagc gttataatta
    21121 attataaata ttgaataatc taaatggata agataatggt attaaaaatt atcttaaaag
    21181 gtgaaataat ctgtatttaa tgtagtacag ttatatcttt aaagcaaggt ggtgaaatga
    21241 tataaataag atatctaaaa gagggtttga tgatagtgat aaaagatggt tttcaagtaa
    21301 agaattaaca agacttataa agtctaaaga agaaatagaa tggttattaa atagggatta
    21361 caaaatagac ccagtcgtta cttttgttgg tgatagatat cagttttcta taagacaaag
    21421 agatgcatta aaaagggcag tctgtactga tgaaaaaaat attataagac aatcaaaaag
    21481 gctttctcta gataaaatca aagaagatac cgtaaatata gatggcttta atttgataat
    21541 atccatagag gtagcattat ctggtggtac tctagtaata ggaagtgatg gcaatataag
    21601 agatttagca ggtcttaggg gaacctataa gattatagat aaaacagaag aagctttgaa
    21661 tctgataggt aaatttttta ataaatacaa tgcacagaat cttaaatttt atttagatgc
    21721 tccagtttct aattcaggaa atttaaagta taggatatta gagcatgcca aaacttgggg
    21781 aattgaaact gaagtagaat tagtaaaaaa tgcagatgtt gtattggaaa aattagatag
    21841 agtagttagt agtgatgcag tcatagttga caagtgtata agttatttta atgtggctag
    21901 aggtataatt gaagagtata ttaaagaatg taatatcata aatttaaata aatagataaa
    21961 tataggtgag aatatataag tatatgtagc aatattctta gtaatacaag taaagtttga
    22021 aaataggaga acgaatacat atcgaatttc ataaaatgtt gtaaaaagac atatgagagg
    22081 atggatatgt gtgaaattaa ctaaactaaa tattaaaaaa tatagagcac ctatatataa
    22141 atatgcttta gcaaatgtaa atttgaggtc tgctaaatct actaattcaa gtatcataac
    22201 agtaatacct cagggagcca aaatggaagt attggatgaa gaagatgact ggattaaggt
    22261 gatgtacaat tctcaagaag gatatgtgta taaggatttg gtatcagtaa gcgaatatgc
    22321 ttggagtaac ttaaacttaa gagaagataa atctacaact tccaatataa ttacagtaat
    22381 tcctgaaaaa tctagggttg aagtccttca agtagatgga gattggagta aggttgtata
    22441 tgatgataaa ataggatatg tttttaatta ttttttatca attgatggga ataaaccaaa
    22501 tgaattagat tataagtatt tttatactga catgattaaa tttgttaacg aaaataacat
    22561 taaaagtact agcgattatc taattgtaac agaccttaga aataaatata cttatatttt
    22621 taagaaagat aatggaggat ggggacaact ttacaagtgg caatgtacta taggcaagcc
    22681 tgagactcca actataacag gtatatttta tataagtgga agaaaacctt cttttggaac
    22741 ggatgagtat tcagttaagt atgctactag aattaaaggt ggatattact atcattctgt
    22801 actatatgat tcaacaggaa gttatataat agatggcaga cttggtgaag ctcttagtca
    22861 tggatgtata agattaagta cggaaaatgc aaagtggata tatgataata taccagatac
    22921 aacaacagtt ataattcatt aagaaaaatt ttgagttttt tattgggata ataattctta
    22981 aattaataga attatatatt aacttctcat aaagagtact atttaaaaag tgtaataaga
    23041 gagtgctatt aacaaaacaa agatattttg aggcactctc ttataaatat acataattaa
    23101 gatattttca taaacaattc tataatctta tctttatcaa agaaaacagg attagcacca
    23161 gcacaagcat ctttcataga gttttctgca agcaattcaa aattaggatt atcaacacct
    23221 acatctttta aagattttgg gattccaacc tcttcagaaa gagcttttat cttatctatt
    23281 acaaagtcaa cacactcttt atctgattta ttatttacat ccattccaat aacttcagct
    23341 attggtcgga atttggcagg ggctgattta gcattttcct cctcaactat tggaagtagc
    23401 atggcattac atactccatg aggtaaatca tataaacctc ctaattgatg agccatagca
    23461 tgtacatttc caagacctgc attactaaag gcaattccat ttaaaaaaca agcataacac
    23521 atttgttctc tagcttctat gtcattacca tttttaacag ctcttggaag gtatttaaat
    23581 atctgcttta tagcatataa ggcagttgaa tctgtaacat cataagcacc attagctact
    23641 acagcttcta tagcatgagt tagtgcatcc ataccagttg ctgctgttaa attagatggt
    23701 ttgctaatca ttaattctgg gtcatttact gtcattgtgg ctagtgaatt ggtatcaacc
    23761 attatcatct ttacatgtct gtcttcatca gttataacat agtttattgt aacttcagca
    23821 gatgtaccag cagtagtagt tatagctatg ataggaagac attttttaga agttttgttg
    23881 ataccttcat agtctctaat atctcctcca ttagtggcta atatagagat agctttacca
    23941 cagtcttgtg gagaaccacc tcctatagtt ataacgaagt cgcaattttc tgattttaat
    24001 attttaagtc ctttattcac attagttaca gttggatttt gtttaacttc atcataaaca
    24061 acaaagtcta catctatctg agataaaata tctgttactt tttttacagt accatttgaa
    24121 actagaaatt tatcactaac aataaatgct tttttagttc ctaatgattt aattgaatct
    24181 ttagcttcat taagacatcc tttcccaagt aaatttattg gtggtacata ataaatgctc
    24241 ataactaaaa tctcctttta ttttcattga tttttatgta aaaatatata tctaacaatt
    24301 ttcactaact tactcataat atatcgtatc ttagattgag ataggattgt tggttcttat
    24361 ataagaactt aattcgtaat tacgattatg attagaattt aacatagtat ttttatcatg
    24421 tcaataaaaa tataaaaaat attataaaaa aaacaaagtt actgtagtta aatcagcaac
    24481 tttgttttta tagtataaat caaataaata cattagttta aaacaaaatt tttaattatt
    24541 atgttttgat atcttccata tacagaatat taatctaatt tattacaatg tcttcattac
    24601 gttcttccat cattgattga atatttttct gagcatttaa gagtaatttt tttatcagtt
    24661 ctattttttc gtcattagct ctaaataaag gcagtgttac actaacagca gctcttatac
    24721 atccattttt tcttattggt acggcaagac attttaggtg ttccattgat tcctcacact
    24781 ctgaagctat ttgtgttctt tgaacttcaa gaagctggtc gtataaaaca tcaaaatctg
    24841 taattgattt ttctgtaaaa ccttttagac catctggata taagcttatt agtttttcct
    24901 tgtcaaaatc acataaaaga gcttttccaa gacctgtaca attagcaggt attttttttc
    24961 caacataaga aataagtcta attggttctg gagaatctac ttttccaata taaagaactt
    25021 cattattgtc aagtatacca agctgacaag tttcagaaca ggaattaact atattagtca
    25081 tttcgtcaat tatatagtta aaaatagttc ttttttcaaa aaatgaagac cctaatgtgt
    25141 aagaacgtat ccctatagaa tatttggatg tgtttttatc aatagtaatg tattttctag
    25201 cattaagtgt atgaactata ggaaagatgc tactttttgg agcattgata acatctgcta
    25261 tttctgtaag agtatatcca ttttcggatt ctgctaatgc ttctaaaata tctaatatcc
    25321 tagctgttgg gcgatgatta tctgaagtca taaatttccc cctcttttta ttaatttaaa
    25381 gtattagaat atgttgattt tagcacacta tacgatattt tacaatgtag aaaataaata
    25441 tgtaaattta tatataaata agctcttgat ttagatacag atagatattt ttttagactg
    25501 tacattaagg aataactaat ttccaaaatg tacctaaaga aagtaagtga tatttagtta
    25561 tataatttaa gtaaatatat gcaatagtta tttttatatg taaatatcaa aatattatga
    25621 acttatattt tatctatttt ttac
//
LOCUS       DAYAOO010000054        25590 bp    DNA     linear   BCT 12-OCT-2024
DEFINITION  TPA_asm: Clostridioides difficile isolate ST8-SSI-h139-18
            SAMN40601845-rid21577343.denovo.054, whole genome shotgun sequence.
ACCESSION   DAYAOO010000054 DAYAOO010000000
VERSION     DAYAOO010000054.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN40601845
            Sequence Read Archive: SRR28438827
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 25590)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 25590)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-MAY-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-MAY-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002157583.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002157583.1
            Genome Coverage       :: 163x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/11/2024 16:19:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 4,038
            CDSs (total)                      :: 3,963
            Genes (coding)                    :: 3,930
            CDSs (with protein)               :: 3,930
            Genes (RNA)                       :: 75
            rRNAs                             :: 6, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 60
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 33
            CDSs (without protein)            :: 33
            Pseudo Genes (ambiguous residues) :: 0 of 33
            Pseudo Genes (frameshifted)       :: 7 of 33
            Pseudo Genes (incomplete)         :: 25 of 33
            Pseudo Genes (internal stop)      :: 11 of 33
            Pseudo Genes (multiple problems)  :: 8 of 33
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..25590
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN40601845-rid21577343.denovo.054"
                     /isolate="ST8-SSI-h139-18"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Denmark"
                     /collection_date="2018"
                     /collected_by="Statens Serum Institute"
     gene            complement(477..1349)
                     /locus_tag="ACGI5H_002468"
     CDS             complement(477..1349)
                     /locus_tag="ACGI5H_002468"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424273.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MurR/RpiR family transcriptional regulator"
                     /protein_id="HFG9698168.1"
                     /translation="MEETNEMKDSKHLISNIQSQYTRLSKGQKLIAQYILNNYDKVAF
                     MTACKLGETVGVSESTVVRFANALGYSGYPKLQAALQELIKNKLTTVQRVEMAHDYSD
                     DFAILNKVLKSDIDNIRSTLEEIDERAFKEASNKLLRARKIYILGMRSSFVVAQYLGF
                     YLDIILDNVHIIRMDMGDAFEQIVRINEEDVIVAISFPRYSKKSYQIVNYAKEKGAHV
                     ISLTDSLFAPVASLADNTLLVKSNMASFVDSLVPALSISNALAISVGMKEKEDIKQHF
                     DDLEQIWKRYSVYE"
     gene            complement(1743..2321)
                     /locus_tag="ACGI5H_002469"
     CDS             complement(1743..2321)
                     /locus_tag="ACGI5H_002469"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428972.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HFG9698169.1"
                     /translation="MAYAKYLTKITDINKFYLENIINEGDIVIDATMGNGYDTRYLAE
                     KVGEKGFVYAFDIQEEAIKSTRKKLEKEGYTDRVKLIFDGHEKMNQYIKEEVSCVLFN
                     LGYLPRAKHSIITKPDTTLKAIKLSLEMLKENGVISIAIYTGHDGGQEEKDCIYNLVN
                     NLNQDEFNVLESKFLNQVNNPPQLILIEKKKA"
     gene            complement(2379..3095)
                     /locus_tag="ACGI5H_002470"
     CDS             complement(2379..3095)
                     /locus_tag="ACGI5H_002470"
                     /EC_number="5.4.99.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890007.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0009982 - pseudouridine synthase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pseudouridine synthase"
                     /protein_id="HFG9698170.1"
                     /translation="MRINKYIASCGIASRRKAEEIILGGRIKVNGSVVKELSFNIDEE
                     KDIVEFDNKKVKPSENYIYIVLNKPEGYITTVKDQFNRPSVIDILKDVRERVYPIGRL
                     DYETSGLLILTNDGDLTYKLTHPKHEIDKMYVASVKGIISDDEIRQFETGLKIEDYTT
                     APAKIRVTKENKEKNYSVCEITIHEGRNRQVRKMCKAINHPVLNLRRISVGKIVLKDT
                     KVGEYRYLTEDEIKYLKSIK"
     gene            3286..4371
                     /locus_tag="ACGI5H_002471"
     CDS             3286..4371
                     /locus_tag="ACGI5H_002471"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435146.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0015562 - efflux transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:1905887 - autoinducer AI-2 transmembrane
                     transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="AI-2E family transporter"
                     /protein_id="HFG9698171.1"
                     /translation="MIIISKENIKYYLIVVFIGILFFKFINTPSDFISSIEGFLKFFS
                     PFLLAILLALLLNPLVMLFEIKFKAHRLLAIFLSYIFIGFILAFAIRLLIPSIANTLN
                     RLINEMPMYTDYIDSFIEKNMSNIYFLKTLIPHIQHSLDNLLKEASNFVGKIPKNFLI
                     YTLSISSMLFNMTMGFILSIYIIYDKEKIALGFKRFLYSSTARNKADNIIEFFRTTHD
                     IFYDYLLGRILDSLIIGIIAFLGFQFVIRIENALFLASIIFLGNIIPYFGPFIGAIPP
                     IAMTILYSPQKTIWVIAFLFILQQLDGNFIEPKVMGNQVGIGAIWVISAILVGQSLFG
                     FIGVFLSVPIAAVVKTYVDKYIDNRLQ"
     gene            complement(4526..5185)
                     /locus_tag="ACGI5H_002472"
     CDS             complement(4526..5185)
                     /locus_tag="ACGI5H_002472"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897209.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipoprotein"
                     /protein_id="HFG9698172.1"
                     /translation="MRGRVILLISILSIFLVGCSFNKKDEINLVEQGKTYLEKHNYKK
                     AMESLSSALEEDSTNENARAMYMQAMRMSNMTEFEELKNYEGAIKELKLIEKIKNGSS
                     VIKEEATKKKEELTKLEKEQNEAEEQRKKKAKDTAGEDRYRVESDARKSSYSGSSKNN
                     KSSSKNNDKKSDSNKSDNNNSSSQNQEKPNNSNPTPAPTPQDTTGGSDSGGNSQNSNN
                     Q"
     gene            complement(5402..6694)
                     /gene="lysA"
                     /locus_tag="ACGI5H_002473"
     CDS             complement(5402..6694)
                     /gene="lysA"
                     /locus_tag="ACGI5H_002473"
                     /EC_number="4.1.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435141.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008836 - diaminopimelate decarboxylase
                     activity [Evidence IEA];
                     GO_process: GO:0009089 - lysine biosynthetic process via
                     diaminopimelate [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="diaminopimelate decarboxylase"
                     /protein_id="HFG9698173.1"
                     /translation="MKLHGTMTVNNDELYIGGVSCLELSKKYQTPLYVFDEALVRQNC
                     REYIEYFKAREGKNKVAYAGKAFLPLYMCNLINEEQMCLDVVSGGELYTAYKSNFPME
                     KVFFHGNNKTKEEINMGLDLGVGKFVVDNFYELDLLEALCEDKGKTQEIYFRITPGIE
                     AHTHDYIKTGQIDSKFGFALVNGDLFRAIEKLSEYKNIKLVGLHAHIGSQIFDVEPYI
                     DTVDIMMNLVKEIKEKFNIQLTEIDLGGGVGVYYSEGDKPKTIKEFCETIITKAETSC
                     KELGIEVPTLVIEPGRSIVANAGSTLYTVGSIKDIKDVRVYVSVDGGMTDNVRPSLYQ
                     ASYECSIVNKINHEAMNHVTIAGKCCESGDILIGDINIMDIKSGDILITTSTGAYGYS
                     MSSNYNKIPRAAVVSVFDGNDKIICKRQSYEDLLALEI"
     gene            complement(6712..7905)
                     /locus_tag="ACGI5H_002474"
     CDS             complement(6712..7905)
                     /locus_tag="ACGI5H_002474"
                     /EC_number="2.7.2.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424287.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004072 - aspartate kinase activity
                     [Evidence IEA];
                     GO_process: GO:0009089 - lysine biosynthetic process via
                     diaminopimelate [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate kinase"
                     /protein_id="HFG9698174.1"
                     /translation="MSIIVQKYGGSSVADTEKIKSIAENIIERRKENPQMVIVVSAMG
                     KSTDEYITLAKELSNEPSKRELDALMSTGEMISASLLSIALNALGCKAISYNAYQLNI
                     KTSGLHGKSQIDDINVNRIKNSLDEGNVVIVTGFQGINEDGDVTTLGRGGSDTSAVAL
                     AVKLNGKCEIYTDVDGIYFTDPRKYSKASKLDEIEYEEMLELASLGAQVMHSRSIELA
                     QKYGVEIYVGRTCGTEKGTYIRGGKDMKLEDKVITGLATSDDDSSITIKDFKAENISS
                     LFEDIATIGISVDMISQTAPILDKISVSFTVPKEELGECKKIVSKYTDEEHLVIDNNI
                     TKFSLVGLGMKNTSGVAAKVFKIFNENGIMIKLITTSEIRITCAINSDDKQVAIEKIA
                     EVFNI"
     regulatory      complement(7987..8155)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00168"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="Lysine riboswitch is most abundant in Firmicutes
                     and Gammaproteobacteria where they are found upstream of a
                     number of genes involved in lysine biosynthesis, transport
                     and catabolism; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="lysine"
                     /db_xref="RFAM:RF00168"
     gene            complement(8266..8883)
                     /locus_tag="ACGI5H_002475"
     CDS             complement(8266..8883)
                     /locus_tag="ACGI5H_002475"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428983.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9698175.1"
                     /translation="MTNMEKEILLLISRVRCVTESQFRKIYGDQKRYNKKNFKKTLRK
                     MCSEYTLKKYPCDVDYYNYKDLSYVYYLNGSKLFKGDDLIKALVGSELVVRINTAGCD
                     VKRFYRNVSVDDVKYDLFIEYTDQFGNIKQVLVDVDLNNEIDISKYENLSKKIDKSTI
                     PFFKVPNVLVVTPDNLSELNDLERYDNEYSINFIDLGLNKLFNCI"
     gene            complement(9053..10753)
                     /locus_tag="ACGI5H_002476"
     CDS             complement(9053..10753)
                     /locus_tag="ACGI5H_002476"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424292.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9698176.1"
                     /translation="MKRYLKTYGVALIIVIIYAFIKLPVLRLDFTSLFSVGIIFFVVA
                     GILDMMLDRNERASKMAKYNFSIAIALLVYIVVVPFITSTPVLHAKSYRELLGKVTES
                     KFTDDISPVSVNDIRLVDEDMAMKLGDKKLGEVPAIGSVSKLGKFHIQNVDGELYWVA
                     PLVHRDIIKWITSLSGTSGYVKVSASNPQDVQLVQEIDGKPIKIVYQPEAYLHQDLQR
                     HLYIHGIVNVGMTDFTLEINDEGRPYWVVSLYEHKIGYGGANATGIATVDAETGKINV
                     YDVKNTPKWVDRIQPQSFVTDQIKDWGVYVNGFLNSVISEKGVLVPTEGTSLVYGNDN
                     RSYWYTGITSSGGDESTIGFMLVDSRTKEARLYKQPGATETAAMKSAEGNVQEKNYEA
                     TFPVMYNILGQPTYVSSLKDKAGLVKRVAFVSVEDYNVLGIGEDKNEALRNYKDALES
                     KGNDLKLDNDLKDEVLEGTVTRISPDVRGGNTNYYVTLDSNKDIIFRATSKVSSELPL
                     TQVGDKVKISYSKEESGVIEMSEFDNLNIANFEDKKAKEKTGTDENTDSKDSENQGNV
                     "
     gene            complement(11150..11713)
                     /locus_tag="ACGI5H_002477"
     CDS             complement(11150..11713)
                     /locus_tag="ACGI5H_002477"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9698177.1"
                     /translation="MNKVYIVTTYTGTILSYLIRNISKKLYTHVSISLNENLKPMYSF
                     GRLNPRNPFIGGFVEENINQGLYAIRKNTVCRVYSLEVDNLQYENLYKNIKLISDYRE
                     DYYYDTMALIYLLMNIQRQSEYKYVCSNFVADMLEKSEIDILNKQAFEVTPNDFYNLS
                     GLTLEYEGLLSEYNSRQHSYVSKIANI"
     gene            complement(11872..12585)
                     /locus_tag="ACGI5H_002478"
     CDS             complement(11872..12585)
                     /locus_tag="ACGI5H_002478"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428988.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2140 domain-containing protein"
                     /protein_id="HFG9698178.1"
                     /translation="MGKVAKILLSLIVIVLVLAGIVVYILTPKERYDVSSQNNKIIDE
                     EYLSKGSYINSMEVVKNPLRMVGKISVSEEEFKNLIYTLMQKHGINELENNFVEMKNG
                     KIKVAGPYKVFGLVNSQYELELRPTLKDGNLVVSLENVKIGKFKLSDKMLEKILSNYN
                     KKVPFEVNGNKITLEKSYLYPITLKNISIKKGNVDLDMEVEIDLKSQINGALGYLKDS
                     GKVQDILNHLINLKKTSVG"
     gene            12877..14541
                     /locus_tag="ACGI5H_002479"
     CDS             12877..14541
                     /locus_tag="ACGI5H_002479"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902971.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0004819 - glutamine-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006425 - glutaminyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine--tRNA ligase/YqeY domain fusion
                     protein"
                     /protein_id="HFG9698179.1"
                     /translation="MSNETNSSNFIKNIIINDLETGKHDSIITRFPPEPNGYLHIGHA
                     KSICLNFGLAKEFNGKANLRFDDTNPLKEDVEYVESIKEDVKWLGFDWNELNFASNYF
                     DEMYKRALILIKKGKAYVCDLTQEEMREYRGTLTEPGKESPHRNRTIEENLDLFERMK
                     NGEFKDGEKTLRAKIDMSSPNINLRDPIIYRISHSTHHNTGDKWCIYPMYAFAHPIED
                     AIEGITHSICTLEFEDQRPLYDWFVKECEMENIPRQIEFARLNINNTVMSKRKLKQLV
                     DEGIVDGWDDPRVPTISGIRRKGYTAEALRNFCSEIGVSKVNSTVDSQMLDYFLRENL
                     QPKAPLTMGVLRPLKLIITNYPEDKIEMLEIENNAKDESQGKRLVPFSRELYIEQDDF
                     MEEPVKKYFRFFPGNEVRLKGAYFVKCTDVIKDENGNVVEIHGTYDPETKSGSGFTGR
                     KVKSTIHWVDAKSAIPCEFRLFEPLILDDIPENEGKHFLKQINPNSLEILQGFVEPTQ
                     IKDAKPFDKFQFVRNGFFSIDNKYTTDEKFVFNRIVPLKSSFKPGK"
     gene            complement(14648..15547)
                     /locus_tag="ACGI5H_002480"
     CDS             complement(14648..15547)
                     /locus_tag="ACGI5H_002480"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435130.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005575 - cellular_component [Evidence
                     IEA];
                     GO_function: GO:0001727 - lipid kinase activity [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0008150 - biological_process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="YegS/Rv2252/BmrU family lipid kinase"
                     /protein_id="HFG9698180.1"
                     /translation="MKKVKLIYNPNSGEKKILSNLDTIIELYQEKNYLLIPYRLTIKE
                     PVKNAFKEVDSSYEHILIAGGDGTVDLVVNAMKELDIKIPIGILPTGTANDFSNALQI
                     SFDIKEAINEIINSKPKKIDIGKVNNKYFINVASAGMFTDVSQRINTDLKNSFGRISY
                     YIKGIEEALYMRKFKIKVSSEEMYYDGDMYLMLIFNGKTAGNINLAYKAEIDDGYLDV
                     IIFKGMPIPKSIPVLISVLRGDYLDQYNGNEILYFKTKKVHIECEDSLITDIDGEKGP
                     DFPLNIECIKDGIEVMGICSEKS"
     gene            complement(15574..16212)
                     /locus_tag="ACGI5H_002481"
     CDS             complement(15574..16212)
                     /locus_tag="ACGI5H_002481"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428992.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lactate utilization protein"
                     /protein_id="HFG9698181.1"
                     /translation="MDQNLNWLNEKRIEKTIKSLENNNMKGYLVSNKEELLKKIEEIV
                     KAGSLVGCGGSMTLFETGVIDFIREKYNFLDRYAKDIKPEEMKEIYRKSFSADAYFTS
                     TNAITEDGELYNLDGNGNRVAAMIYGPDKVIVIAGVNKIVKDVDEAIKRTKTIAAPAN
                     CKRLSTNTGCKTTGICIDCSSPGRICCSYTLIKRQLTPERIHVIFLNEDFGY"
     gene            complement(16549..17547)
                     /locus_tag="ACGI5H_002482"
     CDS             complement(16549..17547)
                     /locus_tag="ACGI5H_002482"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424321.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4003 domain-containing protein"
                     /protein_id="HFG9698182.1"
                     /translation="MEQSFINGKVNLLIENYKALNEVKGSWQMGLIQHSCALAFTLKN
                     KRISPRLVEERIELIKKNTGLFSNFRGYNMFYMATLLSFESNPESSFKMILDIYKELK
                     SEKFWGDTYLPLTASIVYENREKMDYLTCISKMKIIYDYMRKKHPFLTSSDDYCNIAL
                     IAIHSKNLDEDLEYIEKCYEFLNENGFYKGNDLQALSQILLFSDDRTMLKCKKTIELK
                     KAFKENDCKMNYYGYPIIGAISLLDYREDEIIEEIKNVSNKLKEEKGFGNWSLGKSNR
                     VMISSAIVASIYADLIRNENNIGSITNNIFLNIVVAIQIACVMAATSAAIASSSSN"
     gene            complement(17645..18220)
                     /locus_tag="ACGI5H_002483"
     CDS             complement(17645..18220)
                     /locus_tag="ACGI5H_002483"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424324.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9698183.1"
                     /translation="MKLKEALITCVVCSVCLTPLLVNGETKIDADHCKESIVNIDTIV
                     KSGKSFNSKYNQGMEDYKNSDEYKLKVQKEKLQNQLGIKIKKLVPITFEVSYYTSLNQ
                     ENGYGAITATGDDLEDGFVANNHLSFGTKIIVDGKLKTVMDRGSSKYFSNSNAIDVFV
                     PKWSNESESEYYDRVNNMGRHYKKGYIIVEE"
     gene            18536..18799
                     /locus_tag="ACGI5H_002484"
     CDS             18536..18799
                     /locus_tag="ACGI5H_002484"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890184.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9698184.1"
                     /translation="MIKNTKQITVEVNEILLQEMSKITNDENNILTDLINESIVNYIL
                     ENKKHNIENKDLEEVIKFYKKENTEKPKSAARAIAEAKTHTLY"
     gene            complement(19236..19613)
                     /locus_tag="ACGI5H_002485"
     CDS             complement(19236..19613)
                     /locus_tag="ACGI5H_002485"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428999.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0045892 - negative regulation of
                     DNA-templated transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="BlaI/MecI/CopY family transcriptional regulator"
                     /protein_id="HFG9698185.1"
                     /translation="MTITKIPPAELKVMKFIWSSDFTVASKDVIEAMEKLYNWKQTTT
                     LTLLSRLVNKQFLSARKIDRHTHYTVLIGEEEYLHFETKTFLDNMHGSSIESFMKSLF
                     KKGVNEEELNSVEKWVKDIKKDE"
     gene            19954..21066
                     /locus_tag="ACGI5H_002486"
     CDS             19954..21066
                     /locus_tag="ACGI5H_002486"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905716.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HFG9698186.1"
                     /translation="MNAFIRKRNKNYVVYLEFEDEKTGKRKQKNMGTFDKKREASKRL
                     NEVKESLYNDGFLVPSEITVSEFLLDFLNKYSENISLATYNNYVSICKNYINPSIGKY
                     KIQDLHPVHIQNYIDKLSYKLNPQSIKIHINILKLAIKRAYRLKLIKENVMDSIEAPR
                     YKKFKNEIYDREQMIKLLDLAKNTEMELPINLAIGLGLRISEVLGLTWDNIDFEENTI
                     TVNKITSRINGSVILKEPKTESSVRKISSPKELMSLLKEYKIKQNKNLLKSSIRNNNN
                     LLFFNKKCEPIAEDVMSKKFKRFLEKNELPHIRFHDLRHSHVTLLINSKVPIKVISER
                     VGHSNISTTLSVYSHVLKEMDKEASDKISESLFNAN"
     gene            complement(21274..21750)
                     /locus_tag="ACGI5H_002487"
     CDS             complement(21274..21750)
                     /locus_tag="ACGI5H_002487"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435120.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9698187.1"
                     /translation="MVKKRLVAVVISLAMISVGNFSYAHSGGHNSSGGHHNKNKSELT
                     RYYCGGHSAHQHNKGFCPYASTKENSGVTISSVHNEKNHKNYFAEKGYNKGYEDGCKG
                     LYNLSVTEAKSDNLYEKEILKSSYEKGYLIGYNEYKAKKVDDVMKKMLDIPMLASI"
     gene            complement(21949..23574)
                     /locus_tag="ACGI5H_002488"
     CDS             complement(21949..23574)
                     /locus_tag="ACGI5H_002488"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729371.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="HFG9698188.1"
                     /translation="MLQVTGVGLRFGDKELFKDVNLKFTKGNCYGIIGANGAGKSTFL
                     KILSGEIEPNTGSISITDKERMSVLKQDHFEYEEETVLNVVIRGHERLWNIMKEKDAL
                     YMKEDFNEEDGIKAAELEGEFAELDGWDAETNAEKILMGLGITKDMHYKQMKELVGGE
                     KVKVLLAQSLFGKPEILLMDEPTNHLDFKSINWLNNFIMDLEESIVIIVSHDRHFLNQ
                     ICTNIVDVDFGKIQMYVGNYDFWYESSQLALQLAKDQNKKTEEKIAQLKEFIARFSSN
                     ASKAKQATSRKKQLEKLEVEDIQPSRRRYPYVGFTPAREIGNEVLEVHNLTKTIDGVK
                     VLDNVSFRLDRDDKVVFMGDEIATTALLNIVMGELEPDSGEYKWGVTTSQDYLPKNHN
                     KFFDGVEYSLVDWLRQFSEEKSESFIRGFLGRMLFSGEEALKEAQVISGGEKVRCMLS
                     KLMLSNANVLVLDDPTNHLDLESITSVNKGLEKFPGVLLFTSHDHEFISTIANRIIEI
                     TPNGIMDRKMDFDEYLESKEIQDQLAKMYGKDK"
     gene            complement(23912..24931)
                     /locus_tag="ACGI5H_002489"
     CDS             complement(23912..24931)
                     /locus_tag="ACGI5H_002489"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429005.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molybdopterin-binding protein"
                     /protein_id="HFG9698189.1"
                     /translation="MKLIKTIDAVGQVLCHDITQIIPGEFKGRKFKKGHIVKEEDIPV
                     LLSLGKDNLYVWEKSEGMVHENEGALFLKELTAGENLDFSEIKEGKIDFIAACDGLLK
                     IDVDALFDLNCVGEIMMATLHNNFIVNKGLKVAGTRVIPLVIDEKKLEDAKKVVGNRK
                     IVNVVPFKPKKVGIVTTGNEVFYSRIVDKFGPVIEEKVKGFGCEVIGQTICPDDKEII
                     KSAIKEFISQGAELICCTGGMSVDPDDVTPTAIKETGADLVTYGSPILPGAMFLLAYY
                     GEVPIMGIPGCAMYHKTTVFDIVLSRVLIDEKLDKYDIARYGHGGLCMNCDVCTYPAC
                     NFAKI"
     gene            complement(24928..25497)
                     /gene="mocA"
                     /locus_tag="ACGI5H_002490"
     CDS             complement(24928..25497)
                     /gene="mocA"
                     /locus_tag="ACGI5H_002490"
                     /EC_number="2.7.7.76"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890188.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0070567 - cytidylyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0032324 - molybdopterin cofactor
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="molybdenum cofactor cytidylyltransferase"
                     /protein_id="HFG9698190.1"
                     /translation="MINAVIMASGFARRMGANKLLLNYKGCSIIEHVFREVSKIDFHQ
                     VVVVSQYEEVLLLCNKYGFEYIDNKNANIGQSESIKLGVLNSSKCDGYMFFVGDQPFI
                     DNLYIDKIINTFKLDRDFIVIPRYKDMCGNPVIFPYSKKEELLALKEDEKGKTILKNS
                     SKIKYVEVPKEMLFDIDTKMDYERIGGKL"
BASE COUNT         8513 a         4206 c         2655 g        10216 t
ORIGIN      
        1 agtattatat ttctaaaaaa gtttcccttt ccccaaaaat ggctacttaa aaaatcaaga
       61 tttcatacct aactactaat tctatgattt ttaaattttt caacttcttt gtcaaagtta
      121 aaataaaata ctaaaagaca catattatag tgaacaaaaa agatagaaat acatatttta
      181 atataatttt aataagatat tatatactta aatacaaata aaattaattt tataattgtt
      241 aattaaggaa atgatattgt ttagagaaat aaaaaaagca ctctccatga atggaaatgc
      301 tttctttaat aaattagttg acgtagtaaa gatgtattca gaatacatct ttatgttttg
      361 agtctcgaaa tatttatttg tattatttaa acgaaaattt attttttaag tgataatcga
      421 gtatttacta ataaggctat gattctcaat ttcatagcct tattaatata caaactttac
      481 tcatacacag aatatctttt ccaaatttgc tctaaatcat caaaatgctg tttaatatct
      541 tctttttcct tcatcccaac agatatagca agggcatttg aaatactaag agctggaact
      601 agagaatcta caaatgaagc catattactc ttaactagaa gagtgttatc tgcaagtgat
      661 gctactggcg caaataagct atctgttaat gatattacat gggctccttt ttctttagca
      721 taattgacaa tttgataaga tttcttagaa taacgaggga aactaatagc aactattaca
      781 tcttcttcat ttattcttac aatctgctca aaagcatctc ccatatccat tctaattata
      841 tgaacattgt caagtattat atctaagtaa aaacctaaat attgagctac tacaaaagaa
      901 ctcctcattc caagtatata tatttttctc gctcttaaaa gtttgttaga agcttcttta
      961 aacgctctct cgtcaatttc ttctagtgta gaccttatat tatctatatc actttttaaa
     1021 actttgttta gtattgcaaa atcatcggaa taatcatgtg ccatttcaac tctttgtact
     1081 gtagttagtt tattttttat gagttcttga agtgcagctt gtaatttagg atatccacta
     1141 taacctaatg catttgcaaa tcttacaact gtagactcac ttactcctac ggtttcaccc
     1201 aatttacatg cagtcataaa tgcaacttta tcataattat ttaaaatgta ttgtgctata
     1261 agtttttgac ccttactcaa tctcgtatat tgagattgta tatttgatat caaatgttta
     1321 ctgtccttca tttcatttgt ttcttccatt tttttctcct tttagttata taaactattt
     1381 tgttttatta acactgtctt tttctctaaa aattttattt tttatctcaa tttcatctta
     1441 gtttttatca tagcttctta aactcataaa attctaactt ttctgtacct tatacttcac
     1501 atagtatttt cgattaaatt tattatacca tctttccttg cattttttaa tatttatcca
     1561 atatttcttt taaatttttc aatttttact catttaaaag ttatctatct tattttgcat
     1621 atttagatgt atattttgtt ttgagaataa actgttgtat acttattatt taaagtattt
     1681 ttaataggtc acactatata tattaactct taatacaatc ttgtcaagtt ttttagtatt
     1741 tattatgctt ttttcttttc aattaaaatc aattgtggtg ggttattgac ttgatttaaa
     1801 aacttagatt ctaaaacatt aaattcatct tgatttaaat tattgacaag gttatatatg
     1861 caatcttttt cttcttgacc tccatcatgc cctgtatata tggcaatgct tattactcca
     1921 ttttctttta acatttctaa acttaacttt atagccttta aagttgtatc tggtttggtt
     1981 ataattgaat gtttcgctct tggaagataa cccaaattaa ataaaacaca tgaaacttct
     2041 tcttttatat attgattcat tttttcatgc ccatcaaata tcaattttac tctatctgta
     2101 tatccttctt tctctagttt ctttcttgta gactttattg cttcttcttg tatatcaaaa
     2161 gcatatacaa agcccttttc tccaaccttc tcagctagat accttgtatc atacccattt
     2221 cccatagtag catcaattac tatgtcacct tcatttataa tattttctaa ataaaattta
     2281 tttatatctg taattttagt taaatacttt gcatatgcca taatactatt tctccctact
     2341 attaacttta tttcattttt tctcaattta tttttatctt attttattga ttttaaatat
     2401 tttatttcat cttctgttag gtatctatat tctccaactt tggtgtcttt taatactatt
     2461 ttccccacag aaatccttct taaatttaaa actggatgat ttatagcttt gcacattttt
     2521 cttacttgtc tatttctacc ctcatgtata gttatttcac acactgaata atttttttct
     2581 ttattttctt tagttaccct tattttggca ggtgccgttg tgtaatcttc tatttttagt
     2641 cctgtttcga attgtcttat ctcatcatca cttataattc ccttcacact tgccacatac
     2701 attttatcaa tttcatgctt tggatgggta agcttatatg ttaaatcgcc atcattagta
     2761 agtattaata aaccactagt ttcataatct aatctcccta ttggatatac tctttccctt
     2821 acatctttaa gtatgtctat tacactgggt ctattgaatt ggtcttttac tgtagttata
     2881 tatccctctg gtttatttaa tactatatat atataatttt cacttggttt tactttttta
     2941 ttatcaaatt ctactatgtc tttttcttca tcaatattaa aagataactc ttttactaca
     3001 cttccattta cctttattct tcctccaaga attatttctt ctgcttttct tcttgatgct
     3061 attccacaag aagctatata cttattaatt ctcatactta atccttcctt atcttaaatt
     3121 atgtgtgttt aatattttta tcaatgttaa ttttgctaca ttattatact atactagacc
     3181 ttaattaaaa acaagcaaaa aaattattta attttcctaa ataattgtaa tttcttttca
     3241 catactatta atatgtaata gctgactaaa cactatttta aggaagtgat tattatttca
     3301 aaggaaaata taaaatatta tttaatagtc gtgtttattg gaattttatt ttttaaattt
     3361 attaatactc catcagactt tatatctagt attgaaggat tcttaaagtt ttttagccca
     3421 tttttattag ctattttact tgctttactt ttaaatccac ttgtgatgct ttttgagata
     3481 aaattcaaag cacatagact tttagccatt tttttatctt atatatttat aggttttatt
     3541 ttagcctttg ccattaggtt attaattcca tcaatagcta atacattaaa tagattgata
     3601 aatgaaatgc ctatgtatac tgattatata gatagtttta tagaaaaaaa tatgtcaaac
     3661 atatattttc taaaaacttt aattcctcat atacaacata gtttagataa tttattaaaa
     3721 gaagcaagta attttgttgg taaaattcct aaaaacttct taatctatac acttagtata
     3781 tcttctatgc tatttaatat gacaatggga tttatactat ctatatacat tatatatgac
     3841 aaagaaaaaa ttgcattggg atttaagaga tttctatatt cttctactgc tagaaacaag
     3901 gcagataaca ttatagaatt ttttaggact actcatgata ttttctatga ttatttactt
     3961 ggtagaatat tagactctct tattattggt ataattgcat ttttaggatt tcaatttgtt
     4021 atcagaatag aaaatgcttt atttttagct tcaataatat tcttaggtaa tataattccc
     4081 tattttggtc cttttattgg tgcaatccct ccaatagcca tgactatatt atatagtcca
     4141 caaaaaacta tatgggtcat tgcatttcta tttatattgc aacaattaga tggaaatttt
     4201 atagaaccaa aagttatggg taatcaagtt ggtataggag ctatatgggt aatatctgct
     4261 attttggtgg gacaatctct atttggtttc ataggagttt ttctttcagt accaatagct
     4321 gctgttgtaa aaacttatgt tgataaatat atagataatc gtttacaata gattatctct
     4381 actgtgactt taatttttag tttaaaattt aactgctatt tattaaatta tttctcaaaa
     4441 aatatctctt agtaagaaaa aattgctaag agatattttt tataatatat aatttgttca
     4501 ttaaatttat gcatatattt tatacttatt gattatttga gttttgagaa tttccaccac
     4561 tatctgaacc accagtagta tcttgtggag ttggtgctgg tgttggatta ctattatttg
     4621 gcttttcttg attttgagaa gaactgttat tattgtcaga cttattacta tctgattttt
     4681 tatcattgtt tttagaacta gatttattat ttttactact tccactataa gaagatttcc
     4741 ttgcatctga ttcaactcta tacctatctt ctccagccgt atcttttgcc tttttctttc
     4801 tttgttcctc tgcttcgttt tgttcttttt ctaatttagt taactcttct ttctttttag
     4861 ttgcctcttc tttaataaca gaggaaccat ttttgatttt ctctataagt ttaagttcct
     4921 tgattgcacc ctcataattt tttaattctt caaactccgt catatttgac attctcatag
     4981 cttgcatata catagctctt gcattctcat tagtactatc ttcttccagt gcagaggata
     5041 atgattccat agctttttta tagttatgtt tttctaaata tgtttttcct tgctctacta
     5101 aatttatttc atctttttta ttaaatgaac atcctacaag aaatatagat aatatcgata
     5161 ttaataaaat tactcttcct ctcattaaat ccctccttgt catatacttt aaattttatc
     5221 ataattataa agtttttaaa atattttata tttattacaa gaaatttgtt agtaaaacaa
     5281 aaaataagca gatatgctac gaacgataca ataaaccaaa aattaattta gagatacata
     5341 tcctagcaaa tctgctcata ataaacttta atatttaatt tttattatat acttctctat
     5401 tttatatctc taaagctaat aagtcctcat agctttgtct cttacaaatt atcttatcat
     5461 ttccatcaaa tactgatacc actgctgctc ttggtatttt attataattt gaagacattg
     5521 aatatccata tgcaccagtt gatgttgtta taagtatatc tccactttta atatccatta
     5581 tgtttatatc tccaattaat atatctccac tctcacaaca ttttccagct attgttacat
     5641 gattcatagc ctcatgatta attttattca caatactaca ctcataacta gcttggtaca
     5701 acgaaggtct tacattatct gtcatacctc catctacact tacataaacc ctaacatctt
     5761 ttatatcttt tatagaacct actgtataca atgtacttcc tgcatttgca actattgacc
     5821 ttcctggttc tattaccaat gtaggtactt ctattccaag ctctttacat gaagtttctg
     5881 ctttagtgat tatggtttca caaaactctt ttatagtttt aggtttatct ccttcgctat
     5941 aataaacgcc aactcctcca cctaggtcaa tttctgttag ttgtatgttg aatttttctt
     6001 ttatttcttt taccaagttc atcattatat ccactgtatc tatgtatggt tctacatcaa
     6061 atatttgtga acctatatga gcgtgaagac ctacaagttt aatattttta tattcactta
     6121 atttttctat tgctctaaat aaatctccat ttactaaagc aaatccaaat ttagaatcta
     6181 tctgtccagt ttttatataa tcatgtgtat gagcttctat accaggagtt attctaaagt
     6241 atatctcttg agttttacct ttatcttcac ataatgcttc aagcaaatct aattcataaa
     6301 aattatccac tacaaattta cctacaccta aatctaatcc catgtttatt tcttctttag
     6361 tcttattgtt tccatgaaag aaaacttttt ccataggaaa atttgattta taagctgtat
     6421 ataactcgcc tcctgaaact acatctaaac acatttgttc ttcatttata agattacaca
     6481 tgtaaagagg taaaaaagct ttccctgcat aagcaacctt attttttccc tctctagcct
     6541 taaaatattc tatatattct ctacaatttt gtctaactaa agcttcatca aatacataaa
     6601 gtggagtttg atatttttta ctaagttcta aacaactcac tcctccaata tataattcat
     6661 cattatttac agtcatagtt ccatgaagtt tcataatagc ctccccaaat tttatatatt
     6721 aaatacttct gctatttttt ctatagctac ttgcttatca tcagaattta tagcacaagt
     6781 tatacgaatc tctgatgtag ttataagttt tatcattata ccattttcat tgaatatctt
     6841 aaatacttta gcagcaactc cagaagtatt tttcatacca agacctacta aagaaaattt
     6901 agtgatatta ttatcaatca ctaaatgttc ttcatctgta tatttagata ctatcttttt
     6961 acattctccc aactcttctt ttggaactgt aaatgataca cttatcttat ctaaaatagg
     7021 tgcagtttgg cttatcatat ctacacttat acctatagtt gctatatctt caaataagct
     7081 agatatattt tcagctttaa aatcttttat tgttatagaa ctgtcatcat cactagtagc
     7141 taatcctgtt attactttat cctctaattt catgtctttt ccccctctta tatatgttcc
     7201 tttttctgta ccacatgtac gtccgacata gatttcaaca ccatattttt gtgcaagctc
     7261 tatacttctt gaatgcatta cttgtgctcc taaactcgct aactcaagca tttcttcata
     7321 ttcaatctca tcaagtttac tagcctttga atattttctt gggtctgtaa aataaattcc
     7381 atcaacatct gtatatatct cacattttcc atttaattta accgcaagag ctacagcaga
     7441 tgtatctgaa ccacctcttc caagagtggt tacatcacca tcttcgttga ttccctgaaa
     7501 tccagttact atcacgacat ttccttcatc taaactattt ttaattctgt ttacgtttat
     7561 atcatcaatt tgagactttc catgaagacc actcgttttt atatttaact ggtaagcatt
     7621 ataacttata gctttacatc caagtgcatt taatgctatt gataataaag atgctgaaat
     7681 catttcacca gtagacatta aagcatctaa ttccctctta ctaggttcat tactcaattc
     7741 ctttgctaaa gttatatatt catcagtgga ttttcccatg gcagatacaa ctattaccat
     7801 ttgtggattt tcttttcttc gttctattat attttctgct attgatttta ttttttcagt
     7861 atctgctact gaacttccac catatttttg aacaattata ctcatgcttt ctccccctca
     7921 agctaaattt tgataaataa aaacgcccaa aggtatactt tggacgtgta aatttcatag
     7981 accaagtaac cttgtagctc accactttaa aagtgacagc cttatgcata ttctgcataa
     8041 gtccagaaaa tttgtccgtc aacaaaattt cttcggctat ataccctttc atcaattatc
     8101 aacgcttacc agctcctatt gaatactatt gaatacagct acctctaccc taggctcatt
     8161 atttttaatt aatttattaa tatagtttta tcatattcta tataatattg caacaattat
     8221 tttacaaaat gtggcaaatc gatagttttc ttttctaaag ttagcttata tacaattaaa
     8281 tagtttattt aatcctaaat ctataaaatt tatgctatac tcattatcat atctctctaa
     8341 atcatttaat tcggatagat tatctggtgt aactaccaaa acgtttggta ctttaaaaaa
     8401 tggaattgta gatttatcta tttttttaga aagattttcg tatttagaaa tgtctatttc
     8461 attatttaag tcaacatcaa ctaaaacttg ctttatatta ccaaattggt ctgtatattc
     8521 aataaataaa tcgtatttca catcatctac actaacattt cggtaaaatc tttttacatc
     8581 acaacctgca gtattgattc taacaactaa ttctgatcct actagagcct ttattaaatc
     8641 atctccctta aaaagtttac taccgtttaa atagtataca taagagaggt ctttataatt
     8701 ataataatcc acatcacaag gatatttttt tagtgtatat tcactacaca tttttctcaa
     8761 agttttttta aaattttttt tattgtatct tttttggtct ccataaattt ttctaaattg
     8821 agactctgta acacatctaa ccctgctaat taaaagtaat atctcttttt ccatattcgt
     8881 catagtacat tctccttgaa gtattatttg caaagttgta ctaatattat attaatttta
     8941 tgacattaaa tttacaaaga attaaaataa aatagctaat ttttatagaa ttaaattcta
     9001 taaaaattag ctatcactat gttaaatact attatcaatc tttttattta aattatacat
     9061 taccttgatt ttcagaatct ttggaatctg tattttcatc agttcctgtt ttttcttttg
     9121 cttttttatc ttcaaagttt gcaatattta ggttatcaaa ttctgacatt tctattacac
     9181 cagattcttc ttttgaatac gatattttga ctttatcacc aacctgagtc aatggcaatt
     9241 cgctagatac ttttgaagta gccctaaata ttatatcttt atttgaatct aaagttacat
     9301 aataattagt gttaccacct cgcacatctg ggcttattct tgtcactgtg ccttctaata
     9361 cctcatcttt taaatcatta tcaagtttta aatcattacc cttagattct aatgcatcct
     9421 tatagtttct taatgcttca ttcttatctt cacctattcc aagtacatta taatcttcaa
     9481 cagatacaaa tgcaactctc ttaacaagac ccgccttatc ttttaatgat gatacatatg
     9541 ttggctgacc caatatatta tacattacag ggaacgtcgc ttcataattt ttttcttgaa
     9601 cattaccttc agctgatttc attgcagccg tttcagtagc tcctggttgt ttatataatc
     9661 tagcttcttt tgttctagaa tcaactaaca taaatccaat tgtagattca tctccacctg
     9721 aagatgttat acctgtatac caataagacc tgttatcatt gccataaact aatgatgtac
     9781 cttctgttgg tactaaaact cccttttctg atataacaga gtttaaaaat ccattaacat
     9841 aaacacccca gtctttaatt tggtctgtta caaagctttg tggttgtatt ctatccaccc
     9901 atttaggcgt gtttttaaca tcataaacat ttatttttcc agtttctgca tcaacagtgg
     9961 ctattcctgt tgcatttgct cctccatagc caattttatg ttcatataaa cttacaaccc
    10021 aataaggtct tccttcatca tttatttcaa gagtgaaatc tgtcatacca acatttacaa
    10081 taccatgtat gtataaatgt ctttgtaaat cctgatgtaa gtaggcttct ggttggtaaa
    10141 ctatctttat tggctttcca tctatttctt gaactaattg gacgtcttga ggattactag
    10201 ctgatacttt tacataacca cttgtaccac ttagagatgt tatccattta attatgtctc
    10261 tgtgaacaag aggcgctacc cagtacaact ctccatctac attttgtata tgaaattttc
    10321 ctaatttgga tacactccct attgcaggaa cttctccaag ctttttgtca cctaatttca
    10381 ttgccatatc ttcatctaca agacgaatgt catttacact gacagggcta atgtcatcag
    10441 taaatttact ttcagttact tttcccaata gttctctata tgattttgca tgaagtacag
    10501 gtgtagaagt tataaaggga actactacaa tatacacaag caaagctatt gctattgaaa
    10561 aattatattt agccatttta gatgctcttt catttctatc taacatcata tctagtattc
    10621 ctgctacaac aaagaaaatt attcctactg aaaataaaga tgtaaaatct aatcttagta
    10681 caggtaattt aataaatgca taaattatta caattattaa tgcaactcca tatgttttaa
    10741 gatatcgttt catttaatac tcctctctaa aaaatgttat tattactatt atatccatat
    10801 atttacaaaa aataaatatt tatcatattt attatatatt aagatatctt tatatattta
    10861 tagttctgct tattcaacta tatttaacat tatacgtgta tgtataaata ctttttatac
    10921 actgtttgtg ctatccatcc cgcacctaaa ggagtgggat ttttgcacta ttctgtatta
    10981 tatatatcca aaaatgttat aaaaatacaa atattagcag aaatttaaaa actgaagaaa
    11041 gtattctaac taagatttac aaattcttaa tcctatcgaa gttaaactac tatcttcagc
    11101 ctaattatct agcaatattt ttttatatga aaaactctaa atcaagtttt taaatgtttg
    11161 cgatttttga tacataagaa tgttgtctag aattatattc tgataataaa ccttcatact
    11221 ctaaggttaa gccagataaa ttataaaaat catttggcgt tacttcaaat gcttgtttat
    11281 ttaaaatgtc tatctcactt ttttctaaca tgtcagcaac aaaatttgaa catacatatt
    11341 tatattcaga ttgtctctga atattcatta gtaaatatat taatgccatt gtatcgtaat
    11401 agtaatcttc tctataatca ctaattaatt ttatattttt atatagattt tcatattgta
    11461 aattatctac ttctaacgaa tataccctac acacagtgtt ttttcttata gcatataatc
    11521 cttgatttat attttcttca acaaatcctc caataaatgg attccttgga tttagccttc
    11581 caaaagaata cattggtttt agattttcat ttaatgatat tgacacatgt gtatacagct
    11641 ttttacttat attccttatt aagtaagata atatagttcc tgtatatgtt gttacaatat
    11701 agactttatt catcatttcc ccccaatcta gtaactaaat aatattatac acttacaatt
    11761 taatatcata agatattcta acataataaa tgtggtttta caaattttga ttttaaggta
    11821 ctttaatatt atataatata ataaaaatat aaatataagt tttctatatt tttaaccaac
    11881 agatgttttc ttcaaattaa tcagatgatt tagtatatct tgaacctttc cagagtcctt
    11941 taaatatcct aatgccccat ttatttgtga ttttaaatct atttctactt ccatatccaa
    12001 atcaacattt ccttttttta tagatatatt tttaagtgtt attgggtaaa gataactttt
    12061 ttccaaagta atcttatttc cattaacctc aaatggaact tttttattgt agttacttaa
    12121 tattttttct agcattttat cacttagttt aaattttcca attttcacat tctcaagact
    12181 tacaactaag tttccatcct ttaaagtagg tctcaattca agttcatatt gactatttac
    12241 caaaccaaat accttatatg gtcctgctac ctttatttta ccatttttca tttcaacaaa
    12301 attattttca agttcattaa ttccatgctt ctgcatcaat gtatatatta aatttttaaa
    12361 ctcttcctct gaaacagata tttttccaac cattctaagt ggatttttta ctacctccat
    12421 agaatttata tatgagcctt ttgataaata ttcttcatct atgattttat tattttgtga
    12481 actaacatca tatctttctt ttggtgtcaa gatatataca acaattcctg caagtactaa
    12541 aacaataaca attaaactta acaaaatctt tgcaaccttt cccataatcg tctcctttac
    12601 aaatctgtca tcagatttaa aataaattta gataactaac ttcacataat attcttaaca
    12661 atatacatac tataatacag tcttttaaaa attaattcaa ccaatctaat gttttgtaaa
    12721 taaactgtaa aaacatgttt ttagtataaa agttaatatt ttgcataata ctcttaatta
    12781 cacctttatt tttttctaat cttggattaa aattaatatt atgcaataca gtgtagtgtt
    12841 ctgtattata atcaaattaa ataggaggta tagaatatgt caaatgaaac gaactcatct
    12901 aactttataa agaatattat tataaacgac ttagaaacag gaaaacatga cagtatcata
    12961 actcgttttc cacctgagcc aaacggatat ttacatattg gtcatgcaaa aagtatatgt
    13021 cttaattttg gattagctaa ggagtttaat ggaaaagcta atttaagatt tgatgataca
    13081 aacccattaa aagaggatgt tgaatatgta gagtccataa aagaagatgt aaagtggtta
    13141 ggatttgatt ggaacgagtt aaattttgca tctaactact ttgatgaaat gtataagaga
    13201 gctttaatac taataaaaaa gggtaaagct tatgtatgtg atttgacaca agaggaaatg
    13261 agagaatatc gtggtactct aactgaacca ggaaaagaaa gtcctcatag aaacagaact
    13321 attgaagaaa accttgattt atttgaaaga atgaaaaatg gtgaatttaa agatggtgaa
    13381 aaaacattaa gagccaaaat agatatgtct tctccaaata taaaccttag agacccaatt
    13441 atatatagaa tatctcattc aacacaccat aatacaggag ataaatggtg catatatcct
    13501 atgtatgctt ttgctcatcc aattgaagat gcaattgaag gaataactca ctctatatgt
    13561 actttagagt ttgaagacca aagacctctt tatgattggt ttgttaaaga atgtgagatg
    13621 gaaaatatac ctagacaaat agaatttgct agacttaata taaataatac tgtcatgagt
    13681 aaaaggaaat taaaacaact tgtagatgag ggtattgttg atggttggga tgaccctcgt
    13741 gttcctacaa tatccggaat cagacgtaag ggatatactg cagaagcatt gcgcaatttc
    13801 tgtagtgaaa taggggtatc aaaagttaac tctacggtag atagtcaaat gcttgattat
    13861 ttcctaagag aaaacttaca accaaaggct cctcttacta tgggagtttt aagaccttta
    13921 aaacttatta taactaatta cccagaagat aagattgaga tgcttgaaat agagaataat
    13981 gctaaagatg aatctcaagg aaagagatta gttcctttct ctagagaatt gtatatagaa
    14041 caagatgatt ttatggaaga acctgttaag aaatatttta gatttttccc aggaaatgaa
    14101 gtccgtttaa aaggtgctta ttttgtaaaa tgtactgatg taattaagga tgaaaatgga
    14161 aatgtagttg aaatacatgg tacttatgac cctgaaacta agagtggctc tggctttaca
    14221 ggacgtaagg taaaatctac aatacattgg gttgatgcta aatcagctat accatgtgaa
    14281 tttagattat ttgaaccatt aattcttgat gatatacctg aaaatgaagg taaacatttc
    14341 ttaaaacaaa taaatcctaa ttcattggaa atattacaag gttttgttga acctacacag
    14401 ataaaagatg ctaaaccttt tgataaattc caatttgtta gaaatggatt ctttagtata
    14461 gataataaat atacaactga tgaaaaattt gtatttaata gaatagttcc tctaaaaagt
    14521 tcttttaaac caggtaaata atcttacaat caaaaaatga agacttaaaa tataaattac
    14581 ttctactata aataaactta gttagaagta attttttatt tgagtcttca tcatttactt
    14641 taaatgatta acttttttca ctacagattc ccatgacttc tattccatct tttatgcatt
    14701 ctatgttaag aggaaaatct ggtccttttt ctccgtcaat atctgttata agtgaatctt
    14761 cacattctat atgcaccttt ttagttttaa agtatagtat ttcatttcca ttatattgat
    14821 ctaaataatc acctctaagc acacttatca aaactggtat tgattttggt attggcattc
    14881 ctttaaaaat aattacatcc aaatatccat catctatttc agccttatat gctagattta
    14941 tatttcctgc tgttttgcca ttaaaaatca acataagata catatctcca tcataataca
    15001 tttcctcaga agatactttt atcttaaatt tcctcatata caatgcttct tctattccct
    15061 ttatataata agaaattctt ccaaatgaat tttttaagtc tgtgtttatc ctttgtgata
    15121 catccgtaaa cataccagca cttgcaacat ttataaagta cttattattg actttcccta
    15181 tgtctatttt ctttggtttt gaatttatga tttcatttat agcttctttt atatcaaatg
    15241 aaatttgaag agcatttgaa aaatcatttg cagttcctgt aggcaaaatt ccaattggaa
    15301 tttttatgtc taattctttc attgcattta ctactaaatc tacagtacca tcaccaccag
    15361 ctatcaatat gtgttcataa gaactatcaa cttccttaaa tgcattcttt acaggttctt
    15421 taatagttaa tctatagggt atcaataaat aatttttttc ttgatataat tctatgatag
    15481 tgtctaaatt tgataatatc tttttttcac ctgaattagg attgtatata agttttactt
    15541 ttttcattat ttctccttac tcattttatt cttttagtat ccaaaatctt catttaaaaa
    15601 aatcacatgt attctttctg gtgttaattg tctttttata agtgtataac tacagcatat
    15661 tcttcctgga cttgaacagt ctatacatat accagtagtc ttacatccag tatttgtact
    15721 taatctttta caattggctg gagcagctat tgtttttgtt ctttttatag cttcatctac
    15781 atctttaact attttattta ctcctgctat aactattact ttatcaggtc catatatcat
    15841 agcagcaact ctattcccat tcccatctaa attgtaaagt tctccatcct ctgttatcgc
    15901 attagtactt gtaaaataag catctgcaga aaatgacttt ctatatattt ctttcatttc
    15961 ttctggtttg atatcttttg catatctatc aagaaaatta tatttttctc ttataaaatc
    16021 aatcactcct gtttcaaata aggtcataga acctccacat cctactagag aacctgcttt
    16081 aactatttct tcaatttttt taagaagctc ttctttgtta cttactaaat accctttcat
    16141 attattgttt tccaaagatt ttattgtttt ttctattctt ttttcattaa gccaatttaa
    16201 attttgatcc attttaactt cccccttatt tttaatatgc acttaattat ttataaactt
    16261 tattttcttt ataagtttat tttagtacat ctaaaaaaaa atacaatata aaacttaaat
    16321 agttttacat aattttttcc aaaataactt actcaatcaa aaaaggaaag tagatgtact
    16381 attctacttt ccctatattg tatgtagtat ttattgccta aaatctatat attaattata
    16441 tgtttcatat tatataatat cacagttaat taaaatgtaa tactatcttc tttttaaaca
    16501 tataaattgt attattaaat ttaatatatc caacttcaat aaatcttatt aatttgatga
    16561 agaagatgct atagctgcac ttgttgctgc cattacacat gcaatttgaa tagcaacaac
    16621 aatatttaaa aatatattat tagttataga gcctatatta ttctcatttc gtatcaaatc
    16681 tgcataaatt gaagctacaa tagcagaact aatcattact ctattacttt ttcctaaaga
    16741 ccaatttcca aagccttttt cttctttaag tttatttgaa acatttttta tctcttctat
    16801 tatttcatct tctctataat ctaataatga aattgctcct attattggat atccataata
    16861 attcatttta caatcatttt ctttaaatgc ttttttaagt tcaatagtct ttttacattt
    16921 aagcatagtt ctatcatcac taaataaaag aatttgggat aatgcttgta aatcatttcc
    16981 tttataaaaa ccattttcat ttagaaattc ataacatttt tctatgtatt ctaaatcttc
    17041 atctaaattt tttgaatgaa ttgcaataag tgctatatta caatagtcat cactagaagt
    17101 tagaaatgga tgttttttcc tcatgtaatc atatattatt ttcatttttg atatacatgt
    17161 aagataatcc attttctctc tattttcata aactattgat gctgtaagtg gtaaatatgt
    17221 atcgccccaa aacttttcac ttttaagttc tttgtatata tctaaaatca tcttaaaact
    17281 actttctgga tttgattcaa acgaaagtag tgttgccata taaaacatat tatatcctct
    17341 aaaattagag aataatccag tatttttttt aataagctct attcgttctt ccactaatct
    17401 aggacttatt ctcttgttct taagggtaaa tgcaagtgca caactatgtt gtatcaatcc
    17461 catttgccaa gaacctttaa cttcatttaa tgctttgtaa ttttctatta ataagtttac
    17521 ttttccattt ataaacgatt gttccatatt gccctcctag taatatatct cattgtacta
    17581 atagttttat atttattata tatatattaa atactacaat caatacatat tacttcaaag
    17641 aacatcattc ttcaacaata atgtagcctt ttttgtaatg tcttcccata ttattgactc
    17701 tatcatagta ctctgattca ctttcattac tccatttggg cacaaataca tctattgcat
    17761 tagaattact aaaatactta ctagaccccc tatccataac agtttttaat tttccatcta
    17821 caataatctt agttccaaaa cttaagtgat tgtttgctac aaaaccatct tctaaatcat
    17881 ctcctgtagc agttatcgct ccatatccat tttcttgatt aagacttgtg taataactaa
    17941 cttcaaaagt tataggtact aacttcttta ttttaatacc taactgattt tgtagtttct
    18001 ccttttgtac tttcaactta tactcatcac tatttttata atcttccata ccttgattat
    18061 acttggaatt aaagctttta cctgacttta ctatagtatc tatatttact atagattctt
    18121 tacaatgatc tgcatctatt tttgtttctc catttaccaa taatggagtt aaacatacac
    18181 tacatacaac acatgtaatc aatgcttctt taagcttcat aaattccccc cttattattt
    18241 tgatatatta gcatatttaa tattatatgt ctacatttag atttaaatac cacacccatt
    18301 tgctttaaga agttgtctta tatttaattc accttaaaca cttataaatc ctctatctta
    18361 gaatcatata gaataaagct tttatcttta aatatttttt attaatcttt taaaatctaa
    18421 aactacttta tctaattttc tcttttttag aatttaagaa ttaaaattct ataattttaa
    18481 aacatattga atttattttt ttgagatgat ataattttct taagaggtgg ttgatatgat
    18541 aaaaaataca aaacaaatta cagtagaagt taatgaaatt ttattacaag aaatgtctaa
    18601 gataactaat gacgaaaata atattttgac agatttgata aatgaatcaa ttgtaaatta
    18661 tattcttgaa aacaaaaaac ataatattga aaataaagat ttagaagaag tgattaaatt
    18721 ttacaaaaaa gaaaatactg aaaaacctaa aagtgcagca agagctatag ctgaagcaaa
    18781 aactcatact ctgtattaat caaataaaaa agttcctaaa aactaggaac ttttttatat
    18841 taataattat taatatatct caatatttat ctcaaatcta tcaatataag catgtttaat
    18901 acaatctatt gtatacttat cttaccctag aaataatcaa aacaaaaata aaattatgcc
    18961 ctttatatct aaaacaatta atttacatga ttaatataca aaaattctga cttttaaatt
    19021 cgtatacaat atcaaactaa aataatatta atgacaaacc caatataaat taaattcaaa
    19081 caggtttgat tttacatcaa acttattgta ttaatattaa ataacaagac aaaaatattt
    19141 ataaaaatca caaattttac ataaaacttt atatttgatt catttaacta attattgtaa
    19201 aaactattta ttttatgata attaactaca ccaaattatt catctttttt aatatcctta
    19261 acccattttt caacagagtt caattcttct tcatttaccc cctttttgaa caaggatttc
    19321 ataaaactct caatagaact tccatgcata ttatctaaaa aagtttttgt ttcaaaatgt
    19381 aaatactctt cttctccaat aagaactgta taatgtgtat gtctatcaat ttttcttgca
    19441 cttaagaatt gcttatttac taatcttgat aaaagtgtta gtgttgtagt ttgcttccaa
    19501 ttatatagtt tttccatagc ttcaatgaca tcttttgatg ctactgtaaa atctgaactc
    19561 caaataaatt tcatgacttt taattctgct ggtggtatct tagtaatagt catatgattt
    19621 tacactcctc tcaaacttct acataattaa atactatatt aatagacttt tcgagtcaaa
    19681 ggttttattt aaaatatctc atccaaattt attaatacaa aaaatttata tttttattca
    19741 aaattaaaca cacaatctat taatataaag ataaatatct attctataag tataacagat
    19801 tatcaaatta aaattctaat atttgacata atatatacat tttttaaata aatatataca
    19861 atgtattaaa atgtatgcaa ctctatttca aaattatttt gtgatatata tatgttataa
    19921 taaatgtata aaattttgat tggtgggtta tatatgaatg catttattag aaaaagaaat
    19981 aaaaactatg ttgtttacct ggaatttgaa gatgaaaaga caggtaaaag aaaacaaaaa
    20041 aatatgggta cttttgataa aaaaagggaa gcaagtaaaa gactaaatga ggtaaaagaa
    20101 agcttatata atgatggttt tttagtacca agcgaaatta cagtgtcaga atttctatta
    20161 gattttctaa ataaatatag tgaaaatata tctttagcta catataataa ttatgttagt
    20221 atttgtaaga attacattaa tccatctatt ggaaaatata aaatacaaga cttacatccg
    20281 gttcacatac aaaactacat agataaacta tcttataaac taaatcctca atcaattaag
    20341 attcatataa atatattgaa acttgcaata aaaagagctt atagactcaa attaataaaa
    20401 gaaaatgtta tggatagtat agaggctcca agatataaaa aatttaaaaa tgagatttat
    20461 gatagagaac aaatgataaa attattagat ttagcaaaaa atacagaaat ggaattacct
    20521 attaatttgg ctattggatt aggtcttaga atttcagaag ttttaggtct aacttgggat
    20581 aatattgatt ttgaagaaaa tacaataaca gtaaataaga taacttcccg aattaatggt
    20641 tctgttattc tcaaagagcc aaagacagaa agctctgtta gaaaaatatc ttctcccaaa
    20701 gaattaatgt ctttattaaa agaatataaa ataaaacaga ataaaaattt attaaaatct
    20761 tccattagaa ataataataa tttgttattt ttcaataaga aatgtgaacc tattgctgaa
    20821 gatgttatga gtaaaaaatt taaaagattt ttagaaaaga atgaattacc tcatattaga
    20881 ttccatgatt taagacactc acatgttact ttacttataa attctaaagt acctataaag
    20941 gttatatccg agagagtagg acactcaaat ataagtacta ctctaagcgt ttattctcat
    21001 gtacttaaag aaatggataa agaggcttct gacaaaattt ctgaaagttt atttaatgct
    21061 aattaatatt aatttatctt agctttaaat tagcttagct tattgagata gattcattaa
    21121 tattaaatgt atctatctca aattaataac tacttaaata atctgtttta ttttaattta
    21181 tcgcctcagt tattatactt ttttacgaaa aattatactt tacaataaaa aagatattcc
    21241 cttatagaaa atatcttttt aaatactata ttattatata cttgctaaca ttggaatatc
    21301 taacatcttc ttcattacat catctacttt ttttgcttta tattcattgt atccaattaa
    21361 atatcctttt tcatatgaac tttttaaaat ctctttttca tataaattat cagatttggc
    21421 ttctgtgaca cttaaattat aaagcccttt acacccatct tcataacctt tattataccc
    21481 tttttctgca aaatagtttt tatgattttt ttcgttatgt actgaagata ttgttactcc
    21541 agaattttct tttgtactag cataaggaca aaaaccttta ttgtgttgat gtgctgaatg
    21601 tcctccacaa taataacgtg ttaactctga tttattttta ttatgatgac ctcctgatga
    21661 attatgccct cctgagtgag catatgaaaa attccctaca ctaatcatag ctaaactaat
    21721 tactacagct actaaccttt tcttaaccat aatctattcc ccccaaaatg ttatatattt
    21781 ttattatatc atctactata ttatatttaa attcttaata tacaaaatat tactctattc
    21841 tgctaataaa catgtttaaa caatataaaa aacctcctaa tatttgatta aaaatttaca
    21901 cactcatgca tagcatgtct caaatattaa aaggttttat actaataatt atttatcttt
    21961 tccatacatt ttagctaatt ggtcttgtat ctctttactt tctaaatact catcaaagtc
    22021 catttttcta tccattattc catttggagt tatctctata attctatttg ctatagtaga
    22081 tataaattca tggtcatgag aagtaaataa aagcactcct gggaactttt caagtccttt
    22141 atttacagaa gttatacttt ctaggtctaa gtggttagta gggtcatcta atacaagtac
    22201 atttgcattt gaaagcatta gcttactaag catacatcta accttttctc ctccagatat
    22261 aacttgagct tcttttaatg cttcttcacc tgagaataac attctaccta aaaatcctct
    22321 tataaaactt tcactttttt cttcagagaa ctgtctaagc cagtcaacca aagaatattc
    22381 tactccgtca aaaaacttat tatgattttt tggaagataa tcttgagaag tagttactcc
    22441 ccatttatac tctccactgt ctggttcaag ttctcccata actatgttta aaagtgcagt
    22501 agtagctatt tcatctccca taaatactac tttatcatct ctatccaatc taaatgacac
    22561 attatcaaga accttaaccc catctatagt tttagttaaa ttgtgtactt ctaaaacttc
    22621 attcccaatt tctcttgcag gtgtaaatcc tacatatgga tatcttcttc ttgatggttg
    22681 tatatcttca acttctaatt tctctaactg tttctttctt gatgttgctt gtttagcctt
    22741 tgaagcatta gaactaaatc tagctataaa ttcctttaat tgagctatct tttcttcagt
    22801 ctttttattt tggtccttag ccaattgtaa agccaattga cttgactcat accagaaatc
    22861 atagtttcca acgtacattt gtattttacc aaaatctacg tcaactatat tagtacatat
    22921 ttgatttagg aaatgtctat catgtgatac tattataact atagattctt ctaaatccat
    22981 tataaaatta tttaaccagt ttattgattt aaaatctaag tggtttgtag gttcgtccat
    23041 taatagtatt tcaggcttac caaaaagtga ttgtgctaac aataccttaa ccttttcccc
    23101 accaactagt tccttcattt gtttgtaatg catatctttc gttatgccaa gacccataag
    23161 tattttctca gcattagttt ctgcatccca tccgtcaagc tctgcaaact caccttcaag
    23221 ttcggcagct tttatcccat cttcttcatt aaagtcttcc ttcatataca atgcatcttt
    23281 ttctttcatt atgttccaaa gtctctcatg acctcttata acaacattta aaacagtttc
    23341 ttcttcatat tcaaagtggt cctgttttaa aactgacatt ctttctttat cagttataga
    23401 tatactacct gtattaggct ctatttctcc tgataatatt tttaaaaaag tagattttcc
    23461 cgcaccatta gctcctatta ttccatagca attaccttta gtgaatttta agttaacatc
    23521 tttaaatagt tccttatcac caaatctaag tccaacacct gtaacttgta acattaatat
    23581 attttccttt ctttttgctc ataatttatt ttatcataaa actttgataa catttttatt
    23641 atatattatc acgtaaatag tatatttttt atactaaatt tgtgaaatat ttattaaaat
    23701 aatactaaaa attgtaaatt tataaaaatt aacaatctct tatattatac ttataaagaa
    23761 atcaaattgc aactttattc attcttttac acattgaaaa taagttatta taatttctaa
    23821 ataaatatgc tttttttaaa acatcattct agctgttttg tttcatattt aaaaagagta
    23881 cttaatttgt aaatactctt ttttaataac tttatatttt agcaaaatta catgcaggat
    23941 aagtacatac atcacagttc atacaaaggc caccatgacc atatctagct atatcatact
    24001 tatcaagctt ttcatcaatt aaaaccctag ataaaactat atcaaatact gtagttttgt
    24061 gatacattgc gcatcctggt atacccataa ttggaacttc tccgtaataa gcaagtaaaa
    24121 acatagctcc tggtaatatt ggtgaaccat atgtcactaa atcagctcca gtttctttta
    24181 tagctgttgg cgtaacatca tctgggtcta cactcatccc accagtacaa cagataagtt
    24241 ctgctccttg acttataaat tcttttattg cactctttat aatttcttta tcatctgggc
    24301 atatagtctg tcctataact tcacaaccaa agccttttac tttttcttct attactggtc
    24361 caaatttatc aacaattctg ctataaaaca cttcatttcc tgtagtaaca attcctactt
    24421 tcttaggttt aaaaggtact acatttacta tttttctatt accaactact ttttttgcat
    24481 cttctaattt tttctcatct ataactaaag gtatcactct tgttccagct acttttaaac
    24541 ctttatttac tataaaatta ttatgaagag tagccatcat tatttctcca acacaattca
    24601 aatcaaaaag tgcatcaaca tctatcttta atagaccatc acatgctgct ataaaatcta
    24661 ttttcccttc ttttatttca ctaaaatcta aattttctcc agcagttagt tcttttaaaa
    24721 acaatgcgcc ttcattttca tgaaccattc cttctgactt ttcccataca tacaaattat
    24781 ctttaccaag agataataac actggaatat cttcttcttt tactatgtga ccctttttaa
    24841 attttcttcc tttaaattct ccaggtatta tttgagttat gtcgtgacat aaaacttgtc
    24901 caacagcatc tatagttttt attagcttca taatttaccc ccaattctct catagtccat
    24961 ttttgtatcg atatcaaata acatttcttt aggaacttct acatacttta tttttgatga
    25021 attttttaaa atggttttac ctttttcatc ttctttaagt gccaacaatt cttctttctt
    25081 gctatatggg aatatgactg gatttccaca catatctttg tatcttggaa ttactataaa
    25141 atctctatct aatttaaaag tatttataat tttatctata tataagttat caataaatgg
    25201 ctggtctcct acaaagaaca tataaccatc acattttgag ctatttaaaa ctcctaattt
    25261 tatagattca ctttgaccta tatttgcatt tttattatct atatattcaa aaccatattt
    25321 attacacaat aacaaaacct cttcatattg acttactact acaacttgat gaaaatcaat
    25381 cttgctaact tctctaaata catgttctat tatagaacag cctttataat ttaataaaag
    25441 tttatttgct cccattcttc tggcaaagcc tgatgccatt atcactgcat ttatcatata
    25501 tatcatcctt ggtatttata atatattgat agttctatga tttttataat atctctattg
    25561 atattatcta tatatataat atcatataaa
//
LOCUS       DAYAOO010000055        25543 bp    DNA     linear   BCT 12-OCT-2024
DEFINITION  TPA_asm: Clostridioides difficile isolate ST8-SSI-h139-18
            SAMN40601845-rid21577343.denovo.055, whole genome shotgun sequence.
ACCESSION   DAYAOO010000055 DAYAOO010000000
VERSION     DAYAOO010000055.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN40601845
            Sequence Read Archive: SRR28438827
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 25543)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 25543)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-MAY-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-MAY-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002157583.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002157583.1
            Genome Coverage       :: 163x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/11/2024 16:19:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 4,038
            CDSs (total)                      :: 3,963
            Genes (coding)                    :: 3,930
            CDSs (with protein)               :: 3,930
            Genes (RNA)                       :: 75
            rRNAs                             :: 6, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 60
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 33
            CDSs (without protein)            :: 33
            Pseudo Genes (ambiguous residues) :: 0 of 33
            Pseudo Genes (frameshifted)       :: 7 of 33
            Pseudo Genes (incomplete)         :: 25 of 33
            Pseudo Genes (internal stop)      :: 11 of 33
            Pseudo Genes (multiple problems)  :: 8 of 33
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..25543
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN40601845-rid21577343.denovo.055"
                     /isolate="ST8-SSI-h139-18"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Denmark"
                     /collection_date="2018"
                     /collected_by="Statens Serum Institute"
     gene            complement(30..872)
                     /gene="licT"
                     /locus_tag="ACGI5H_002491"
     CDS             complement(30..872)
                     /gene="licT"
                     /locus_tag="ACGI5H_002491"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897844.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="BglG family transcription antiterminator LicT"
                     /protein_id="HFG9698191.1"
                     /translation="MIIQQIYNNNVVLVLDENIKKELILTGCGIGFQKKKGQEIDKSK
                     IERTFVIQDESFLDKISKLASQVDEKFFEVSTEIIAYAEENLNTKLYEYIYVALTDHI
                     AFAIKRYHENITIKNDLLHEIKRIHKKEYEIGKWAVDYINKEFDVKFPVDEAGFIAMH
                     IVNSNYKGSSKESLLITKIVKDILNIIRYYYRVEFKEDDINYDRLLTHLKFFAKRLVK
                     KEKINDTNNEIIDIIKVKYEKDYDCAYKIKTHVEKNYDYYVSQDELLYLTLHIKRVIS
                     VLNL"
     gene            complement(1133..3175)
                     /locus_tag="ACGI5H_002492"
     CDS             complement(1133..3175)
                     /locus_tag="ACGI5H_002492"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728484.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_process: GO:0006814 - sodium ion transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cation:proton antiporter"
                     /protein_id="HFG9698192.1"
                     /translation="MSILVTLLGLLVCTTISTVFSKKWSNIPLAIYQIVLGIILSILP
                     FKFSFSFNPEIFVICIIAPLLFSEGQNVSRKELLELRKPILLLAFGLVLITVFAGGIF
                     IHFLIPGMPLSVSFALAAVISPTDLVAVKSITQGLNFPKNMMSILEGESLLNDAAGVV
                     AFKVAVLATVTGVFSIEEAGIQFMITAFGGIIVGSILGYIIIKIRLSLHKWNLEEIPM
                     VIVIQIMTPLFVYFVAEEIGVSGILAVVMAGIAHGIEKEHLQNTTTKLRIISDNTWYV
                     LEYVLNGFVFTLLGFLLPSIYTGLSSKNENMALELTFISTLIVLILFVIRFIWVYLWH
                     NSFIKPKKNPLNNFFVGFLGFKDEEVVKESISKCKYSLIVATCGVHGTFTLATALSIP
                     FYLADKDVFPMRDTVLFISSEVILISLVLATVLLPRLLKNNVQESEPLLSDKEAYKLI
                     LKEAILKLSNEKAQEVQPVIHDLNEQLVDSEKGILNTPDNKLISMMIAEADQQGLLAV
                     LKLLEDGKISDRAFKLYRFYITKSRKSVQKSIFKIVKLKISMWIINRKVKKEVKEKIT
                     KIVSENKEIIKEFHHAYALSTKTAISFINKNTDEDNRHEALIAIRFYNRYLNWITRKI
                     QNDDKFEARVEYYRVMAIQSQRDSVQQLVETKQISREVAKELLENILYDEMMMIES"
     gene            complement(3327..4298)
                     /locus_tag="ACGI5H_002493"
     CDS             complement(3327..4298)
                     /locus_tag="ACGI5H_002493"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427052.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HFG9698193.1"
                     /translation="MKKEESLLKVEGLKKYFEVKSGLFDKEIKCVKAVDGISFDLKKG
                     ETLAIVGESGCGKSTAGRTILRLIEKTEGKVEFNGVDIYKLEKEELRKLRPKMQMIFQ
                     DPYSSLNPRLNVEQIISEAVIEHNLVPKNEIKDNILNVVESCGLSKYHLNRKPGEFSG
                     GQRQRIGIARALALNPEFIVCDEPVSALDVSIQSQIINLLMDLQDKYKLSYLFISHDL
                     SVVNHIAHRVCVMYLGSIIEIATKGELYLHSQHPYTKALMSAVPIQDPTIKKNRIILK
                     GDIPSPTNPPSGCKFHTRCPYCKEICKKEIPVLKEISRNHFVACHLV"
     gene            complement(4299..5276)
                     /locus_tag="ACGI5H_002494"
     CDS             complement(4299..5276)
                     /locus_tag="ACGI5H_002494"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454983.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HFG9698194.1"
                     /translation="MSKALIEVKDLKVYFHTDKGIVKSVNEVSFNINEGETIGIVGES
                     GCGKSVTAMSLMKLLPTSKIEGGEIIFRGKDILKMNEDELMGIRGNEISMIFQEPMTS
                     LNPAFTIGSQIIEGIMIHQDLSKEEAKKKVIDMIKLVEIPRAEEIYNSYPHELSGGMR
                     QRIMIAMALSCNPKLLIADEPTTALDVTIQAQILDIMKNIKEKLNTSIMMITHDLGVV
                     AEMCDKVLVMYAGKIIEVAEVVELFKNPKHPYTIGLLKSKPALGKNKDKRLYSIPGQV
                     PNPIGMPDSCYFSDRCEKVCDKCRTQIPPLIELNSGHSIACWLYKKEEI"
     gene            5495..7054
                     /locus_tag="ACGI5H_002495"
     CDS             5495..7054
                     /locus_tag="ACGI5H_002495"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427055.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HFG9698195.1"
                     /translation="MKFKKLASLILVSSLMLTFTACASNDKDKSSGSKSGGTVVIPMA
                     SDPDIINGAFANVKEDSLASNIVYAPLYTYEKGNLVNYLAEKVDFKDSKELTIKLKSN
                     LKWHDGKPITAEDVLFTFNTVLDEKQNSPSRQYLLVGEKPVKVEKIDDLTVKITLPTA
                     SESFLYGISKISPIPKHVFEGESNIAKSEKNNNPVGSGAFKFKEWKKGESIVFEKNAD
                     YFGGESKADSIALKIIPNEASQEAALNNGEISLMKTSAEGYEKAKSNSNLQTYTYSEE
                     RLNYIVFNQNISNMANKEVRQALSYALNRNEMIESAYGKEGSVPAKSILVPEADFYTE
                     EGVEGYDQDTNKAKDLLDKSGVKIDKLKIGYNTGRFGHKNYALVAQQELKKIGIEAEI
                     VPYESKAFFNILFSNSTECDMYVNGYAWGLEPNPYRGMFETGQYCNQTKYSNAEIDAL
                     WEKGFTELNKEKREEIYKQIQQDISKDAPIYTIDYEQNLMAAQKNLKGIKDAKPSPAI
                     LFEDWSKLYVE"
     gene            7160..8119
                     /locus_tag="ACGI5H_002496"
     CDS             7160..8119
                     /locus_tag="ACGI5H_002496"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897855.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HFG9698196.1"
                     /translation="MLKLILNRVKVLIPMLILISILSFGLLELAPGDPADAYINPLMS
                     SQDIENIRVNMGLDKPAYIRYLNWLKNTLSGNLGISYINHMPVTEQIMEKMGNTFILM
                     GTSLIFSILVAIPLGIFLAVNKNSITSKVSSVFNYIGVSIPSFWIGMILISIFSVKLN
                     IFPSGGMHTIGNDSIGDLAKHLVLPVITLGLYNTAIFTNYVEASVNEQLKKQYVITAR
                     AKGLSEKVILFKHVLKNSLTSLVTILGMSIQKLVTGAFVTEVVFSWPGMGRLMIDSIF
                     SRDYTVIMAITMLSALFLILGNLVADILYLLIDPKIKSSKGGF"
     gene            8122..8934
                     /locus_tag="ACGI5H_002497"
     CDS             8122..8934
                     /locus_tag="ACGI5H_002497"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416032.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HFG9698197.1"
                     /translation="MFTSILKKLKKDKSFAFACITLSIIIILIIASFILNIDSNAIDT
                     TSKLQEPSLKHIFGTDELGRDYFSRALYGGRISLSVGILSMLISVVFGTAVGVISGYI
                     GGKLDQFLMRLVDMLMSIPSFLVLIVLNTYLTPKVSTIILIIGFLSWMEVSRIVRGET
                     LKIKENEYCLAAKATGIKTRNILLRHIVLNLKETIVVAGSLNIANAILTESALSFLGL
                     GIQLPLASWGNMLQDAQRHIFDKLYLAVFPGLLIFLTVMSLTIISKKFSSNT"
     gene            complement(9150..10052)
                     /locus_tag="ACGI5H_002498"
     CDS             complement(9150..10052)
                     /locus_tag="ACGI5H_002498"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416031.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR substrate-binding domain-containing
                     protein"
                     /protein_id="HFG9698198.1"
                     /translation="MDIKQLKYFVEIVKSGFNLSIASKTLHISQPALSQIIKNFEESE
                     DVYLFERYKGRLNGLTPAGERFYVNAEHIINEYKNMMEDLREDSVQFKGKVRIGIPPL
                     ILGIAFSDVVAQLVANNPDIEFDIVEKGAYDLNRMLILQELDYAVLLHPHKIDKSVVT
                     EHVLQEDELTAFLNINHPLAKKDKIDWNDLNEQLLAIFNPTFMIHHKLMQKFTDENVK
                     LKRYIMSGSWDFLLLSTTNSDFITILPSPVHDFFENSKIIEKPFNHPITWKVILCRPK
                     KERYSHVDQHVFKFIIDFFSKKNS"
     gene            10407..11585
                     /locus_tag="ACGI5H_002499"
     CDS             10407..11585
                     /locus_tag="ACGI5H_002499"
                     /EC_number="2.3.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416030.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016747 - acyltransferase activity,
                     transferring groups other than amino-acyl groups [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA C-acetyltransferase"
                     /protein_id="HFG9698199.1"
                     /translation="MKDVVIVSAVRTPIGSFGGVFKNTSAVQLGTIAVKEAISRVRLN
                     LSEIDEVIIGNVLQTGLGQNVARQIAINAGIPNSVPSYTVNKLCGSGLKSVQLAAQSI
                     TSGENDVVIAGGTENMSQAPYIVPTARFGSKMGDITMVDSMLTDGLIDAFNQYHMGIT
                     AENIATKFEFTREMQDKLALESQNKAENAIKNNRFKEEIVPVDVLIRRGKIETIDKDE
                     YPKLGMTFEGLSKLKPAFKKDGTVTAGNASGINDGAAMLILMSQQKADELGIRPLAKI
                     KSYASAGVEPEVMGTGPIPATRKALKKAGLSINDIDLIEANEAFAAQALAVKNELQID
                     SSKLNVNGGAIALGHPIGASGARILVTLIYEMQKRKVETGLATLCIGGGQGISMVVSR
                     "
     gene            11594..12250
                     /locus_tag="ACGI5H_002500"
     CDS             11594..12250
                     /locus_tag="ACGI5H_002500"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427064.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008410 - CoA-transferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="CoA transferase subunit A"
                     /protein_id="HFG9698200.1"
                     /translation="MNKIVSIDEALSHVKDGDTIMVGGFMANGSPENLIDYLCSKNIK
                     DLTLICNDTGFIDKGVGKMVVNKQFKKIIASHVGLNKETGRQMNNNETDVELVPQGTL
                     AEQIRAAGYGLGGILTPTGIGTLVEEGKQKIVVDSKEYLLEKPIYADVALLFASKVDK
                     AGNLVYKGSMNNFNNLMASAAKITIVEADEIVEIGDIDPNEVNTPGIFVNYIVEGGNL
                     "
     gene            12250..12915
                     /locus_tag="ACGI5H_002501"
     CDS             12250..12915
                     /locus_tag="ACGI5H_002501"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008410 - CoA-transferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="3-oxoacid CoA-transferase subunit B"
                     /protein_id="HFG9698201.1"
                     /translation="MDKLEMQEYIANRVSKELKDGAVVNLGIGLPTKVANYIPDNVNV
                     ILQSENGFLGLGSAEDGNSSDETIVNAGGQPVTILPGGCFFDSATSFGIIRGGHVDIT
                     VLGALQVDKYGNIANYMIPGKMVPGMGGAMDLVTGAKKVIVAMEHTSKGSAKILNNCT
                     LPLTATNAVDLIVTEMGVMEVTSDGILLKEINPAFTLDDVISATEAPLILSDSLNGKI
                     SVV"
     gene            13020..13796
                     /locus_tag="ACGI5H_002502"
     CDS             13020..13796
                     /locus_tag="ACGI5H_002502"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890906.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-hydroxybutyrate dehydrogenase"
                     /protein_id="HFG9698202.1"
                     /translation="MVKDKVVFVTGAASGIGKQIAESFLKNGAKVMFSDINQEALNNT
                     ITELQKKGYDCMSVKCDVTKEEEINHAIDKTVEKYGRLDILINNAGLQHVSMIEDFPT
                     DKFEFMIKIMLTAPFIATKKAFPIMKKQGFGRIINMASINGVIGFAGKAAYNSAKHGL
                     IGLTKVAALEAADSGITVNALCPGYVDTPLVRGQFNDLSKTRNIPLENVLEEVLYPLV
                     PQKRLLDVQEIADYAMFLASDNAKGITGQACLLDGGYTAQ"
     gene            13858..15192
                     /locus_tag="ACGI5H_002503"
     CDS             13858..15192
                     /locus_tag="ACGI5H_002503"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728489.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GntP family permease"
                     /protein_id="HFG9698203.1"
                     /translation="MSIIAPIGIIIGIIAIIYFSVKEIHITIAAPIATLIVVILNKMD
                     VVTSMLGADKNNYMGALGNYIMSYFAIFLLGSILAKFMEESGATVSIADFILNKFGSN
                     HPYRVLVAIFIVSFILTYGGISLFVVMFAVIPLARTLFKKLDISWNLIQIPLWLGIAT
                     ITMTIIPGTPAIQNVIPIQYLNTSLTAATIPSIVGSIGCATFGLVYMKYALNKSIRKG
                     ETYATYTSELEEESLDRELPGFFASIFPLLALVIIAITGSTFGSEFMKKNVIYIALIV
                     AILLSAFLFHKFLSSKIQTLSIGASGSIGPIFATSSAVAFGAVIMAAPGFDVFSKLIM
                     SIPGSPLISLTVLTSTMSAITGSSSGALGIVMPNFADYYLSTGLNPELIHRVATIASN
                     ILTIVPQSGVFLTFLSLSKLTHKTGFKETFIVVAVGSLIAEIIVITLGLLMY"
     gene            15688..16620
                     /locus_tag="ACGI5H_002504"
     CDS             15688..16620
                     /locus_tag="ACGI5H_002504"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018112861.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CAP domain-containing protein"
                     /protein_id="HFG9698204.1"
                     /translation="MMRRNIPTKLKTILALGVLTLATASSAVTASASSLENNVNISNK
                     SLVYSNTKYKFSAKPNCSVKPELKPDKDNSCKDKNHNDKNCNNTNKPEDNNNSDSTNK
                     PDNNKPESNKPEDNNNSGSTNKPNNNKPESNKPEDNNNSGSTDKPDNNKPESNKPEDN
                     NNNNSDSTNKPDDNNNSGSTSESFSAYQKEVVDLVNIERAKAGLNPLTLDSSISNVAT
                     KKSQDMIDNNYFSHNSPTYGSPFDMLKKFGISYKTAGENIAMGQKTPKEVVNAWMNSE
                     GHRKNIMNPNFSKIGVGVAQKSGGSIYWTQIFVG"
     gene            complement(17012..20551)
                     /gene="nifJ"
                     /locus_tag="ACGI5H_002505"
     CDS             complement(17012..20551)
                     /gene="nifJ"
                     /locus_tag="ACGI5H_002505"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009900447.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005506 - iron ion binding [Evidence IEA];
                     GO_function: GO:0016903 - oxidoreductase activity, acting
                     on the aldehyde or oxo group of donors [Evidence IEA];
                     GO_function: GO:0030976 - thiamine pyrophosphate binding
                     [Evidence IEA];
                     GO_process: GO:0022900 - electron transport chain
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate:ferredoxin (flavodoxin) oxidoreductase"
                     /protein_id="HFG9698205.1"
                     /translation="MAKFMKTLDGNTAAAHVAYAFTDVAAIYPITPSSTMAEVVDEWA
                     SQGRKNIFGQTVNVVEMQSEAGASGTFHGSLQGGALTSTFTASQGLLLMIPNMYKVAG
                     ELLPGVFHVSARALASQALSIFGDHQDVMAARQTGCVLLASGSVQEVADIAPVAHLAA
                     IEGRLPFIHFFDGFRTSHEIQKVELLENEDYASLLNFEAVQAFRDNALSPNHPVARGT
                     AQNPDIYFQTREASNKYYQNIVGIVEKYMEKMSNLTGRKHSLFDYYGAEDAKYVLIAM
                     GSVTETIEETIDYLNAKGEKYGLVKVHLYRPFSMKHFLDAMPSTVERICVLDRTKEPG
                     STGEPLYLDVRDVFYGKENAPMIIGGRYGLGSKDTTPSDIKTVFDNLVSEQPKNGFTV
                     GIVDDVTNTSLTPSEPIKIASKGTIRCKFWGLGSDGTVGANKQAIKIIGDHTEKYAQA
                     YFDYDSKKSGGITMSHLRFGDTPIRATYLIDEADYIACHKQSYVYQYDLLKGLKKGGT
                     FVLNTIWDQAGLEEHLPAHMKQYIAKNDIKFYTVNAVKLGQEIGLGNRINMIMQSAFF
                     KLAEIIPEEDAVKYLKDSIVKAYGKKGEKIVNMNYAAVDAGINALVKVEVPASWENAV
                     DADKGEVKEPEFIKNILRPMTAQEGNNLPVSTFNGIEDGTFPCGTAAYEKRGIAVDVP
                     EWIIDNCIQCNQCSFICPHSCIRPVLVTEEELANAPEGFEAKKALGKGLEGLKYRMQL
                     SPLDCTGCGNCADICPAKEKALVMKPIDTQLDTELDNWAFAVNPDEVAPKGDVMPVNT
                     VKGSQFRQPLMEFSGACAGCGETAYIKVVTQLYGDRMMIANATGCSSIWGASAPSIPY
                     TCNHEGKGPSWANSLFEDNAEYGFGMYTAVKQIRNKIVDAMTELVSMGICEDAKAVFT
                     EWLDSRNDGEASKVASAKVVELLEKPACDCTDEKAKELVKAIKDRKDYLVKRSQWILG
                     GDGWAYDIGYGGLDHVLASGEDVNVLVFDTEVYSNTGGQASKATPAAAMAKFAASGKK
                     SRKKDLGMMAMTYGNVYVAQVAMGADKNQFIKAVIEAEKHDGPSLIIAYAPCINHGLK
                     EGMGRTVANEAQAVACGYWHLYRFNPEVKAEGKNPFTLDSKEPTASFKDFILAQVRYS
                     AIAKQFPEEADGLFAKAEADAKERYEGYKKLAE"
     gene            complement(21069..21638)
                     /gene="pduL"
                     /locus_tag="ACGI5H_002506"
     CDS             complement(21069..21638)
                     /gene="pduL"
                     /locus_tag="ACGI5H_002506"
                     /EC_number="2.3.1.222"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861641.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate propanoyltransferase"
                     /protein_id="HFG9698206.1"
                     /translation="MKLPIALSNKHVHLSQADIDVLFGAGHELTKFKPLSQPGQYACE
                     EKVDLVGPKGTLKGVRVLGPARAHTQVEISLADGFPLGVKAPIKESGDIAGTPGVKLV
                     GPAGEVEMKEGVIVASRHIHMSNEDAAKFGVTDKQIVKVKTSGPRALVFENVLVRASD
                     SFNLEMHVDMEEGNAAGVKNGDLVELIVD"
     gene            complement(21710..22318)
                     /locus_tag="ACGI5H_002507"
     CDS             complement(21710..22318)
                     /locus_tag="ACGI5H_002507"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890914.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0009055 - electron transfer activity
                     [Evidence IEA];
                     GO_function: GO:0010181 - FMN binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="flavodoxin family protein"
                     /protein_id="HFG9698207.1"
                     /translation="MDSNDKKGLKSPEIIIINGSPRINKNCSFIANEVKAMLEECGLS
                     CKIFNIYNMDIEYCTACGFCEKTGYCKFNDDMKPLYKMFDDSKGTIVISPVHFDSISA
                     KLKTVVDRTQAIYASKYVLNKPSIDRSKKRIGMYIAVGGSKSYDSQFKGGQIVMDFFF
                     KSINTKLLHNIYLNNTDDVSYIDNQEFKDIIYKNLKIYIDSI"
     gene            complement(22326..24089)
                     /locus_tag="ACGI5H_002508"
     CDS             complement(22326..24089)
                     /locus_tag="ACGI5H_002508"
                     /EC_number="3.1.3.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427079.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004722 - protein serine/threonine
                     phosphatase activity [Evidence IEA];
                     GO_function: GO:0005515 - protein binding [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0006470 - protein dephosphorylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GAF domain-containing SpoIIE family protein
                     phosphatase"
                     /protein_id="HFG9698208.1"
                     /translation="MTNGSYKMKNLVEISAMVTESTDFFNIKDDIIEKMLEVVHPTKA
                     CVNLFYKNDSKYAYLVCSQTLEYVPQIFPINSLKGAKIDFDTYPEYIHEAVNEKKIIY
                     VENVFEDSRAEGERDLAKAEGYIGRIVFPFIINNVVVGFMTCFLKEDDYITEQDIDFI
                     SSVASLLSLSIEITNKNNNVQILIDKLRGSISAINEATKKLYLNKSIDGFLENLSKQA
                     CNITNSKEALIIINSHHNKDAIVSCYNVEQKKKTNLYPMIDMFLKKESLGGYLNNLKP
                     CSKKGINLESYIYYKLQDKNDTIGCIVCANSKNYTSDDLNILSILSKQVSVGMQLYEH
                     NEKEVKHKVLENELNILNKQQQLIMDKGKMDCNDEKELYFYHKPARVVGGDFYYATKV
                     DDEHIVYIVADVMGHGMVSNYVVAMIKGAFKVLCNQYNTPREIMTNLNRMLYDEFDKM
                     GVFTTCLIGIIDTKENMITVSNAGHYSPVVVKKDGTIENNLNCKKGIPIGIMEDATYE
                     NNTLSMEDYAMVCMYTDGILEIKNSSKEEYGINRLENFLKENFRLNQQLIVENLKLDL
                     KNFSSKDNYDDDILIVMLKDR"
     gene            complement(24132..24593)
                     /locus_tag="ACGI5H_002509"
     CDS             complement(24132..24593)
                     /locus_tag="ACGI5H_002509"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009906048.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9698209.1"
                     /translation="MLNGIIKLFYSEIVKTKINNLDSSGYSLRDECKEIRNITLKIDS
                     VFFKLLKLAFGSILLMVAFNLNMVLGIGVFLVGVVYILYKRNMEEQVKEHINNVKNNI
                     DISKITFMDEKGRTGLNALITLLLIGLLTGFNWILVASFVVVFVFTIKNVC"
     gene            24783..25244
                     /locus_tag="ACGI5H_002510"
     CDS             24783..25244
                     /locus_tag="ACGI5H_002510"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416014.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9698210.1"
                     /translation="MQIEQLDLETRNKIYCYTKKILRKYQKGITSGKLTADKFADNIL
                     SQDFISSILNEKIVNETNFKISYRNYIETLINIQNENLSNLRKKSTKTAKCFNISQIT
                     QLKNLLSNTGYNLLIPYKYLTARDIEGIVTLINTGSIELGNERIYNYISKV"
     gene            complement(25337..25507)
                     /locus_tag="ACGI5H_002511"
     CDS             complement(25337..25507)
                     /locus_tag="ACGI5H_002511"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416012.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9698211.1"
                     /translation="MSSVNFEDLKNKFINSDLDEKIRIYTTTEGLSVEQFKELLKYYP
                     IQHLSKLEKALG"
BASE COUNT         8813 a         4042 c         3358 g         9330 t
ORIGIN      
        1 ctatacattc tgtattaaac tactctttat tataaattca gtacagatat aactcttttg
       61 atatgtaatg ttaaataaag tagttcatct tgacttacat agtaatcata attcttttct
      121 acatgagttt ttattttata tgcacaatca taatcctttt catactttac tttaattata
      181 tctataattt cattatttgt atcattgatt ttttcttttt ttactaatcg ttttgcaaag
      241 aattttaaat gagtcagaag cctatcataa tttatatcat cttctttaaa ttcaactcta
      301 taataatatc ttataatatt tagtatgtct tttacaattt tagtaattaa cagtgattcc
      361 tttgaacttc ccttatagtt tgaatttact atatgcattg ctataaaacc agcttcatct
      421 actggaaatt tcacatcaaa ttctttattt atataatcta cagcccattt cccaatctca
      481 tattcttttt tatgtattct ttttatctca tgtagtaaat cattctttat agttatgttt
      541 tcatgatatc ttttaattgc aaatgcaata tggtcagtaa gtgctacata aatatattca
      601 taaagtttag tattcaaatt ctcctctgca taagcaatta tttcagtact aacctcaaaa
      661 aatttctcat caacctggct tgctagttta ctaattttat ctaaaaagct ttcatcttgt
      721 attacaaaag ttctttcaat tttactttta tctatttctt gacctttctt tttttgaaac
      781 ccaattccac atcctgttaa tattaattct ttttttatat tttcatctaa aactaataca
      841 acattattat tataaatttg ttgaataatc ataatcaata tctctcccaa aatacaattt
      901 cccttattca taaaaaaata cctaaattaa gatacaattc acctgtatac cttaacctag
      961 gtattgcctg cttaccagta acaatccagc ttgttaacgc ttatatattg tattcaattt
     1021 atggttttat tctattataa ataaatatat atgtcaagta aattattgaa aactatttcc
     1081 tattttttag tattaatttt aacatcaaaa atcaaatttt attccattat atttatgatt
     1141 ctatcatcat catttcatca tagagaatat tttccaataa ctctttagcc acttctcttg
     1201 atatttgctt agtttcaact aattgttgaa cactgtctct ttgactttgt atcgccatta
     1261 ctctgtagta ttctactctt gcctcaaact tatcatcatt ttgaatcttt ctagtaatcc
     1321 aattcaaata acgattatag aatctgattg ctattaaggc ctcatgtctg ttatcttcat
     1381 cagtattttt atttataaat gatatagcag ttttagtaga aagtgcatat gcatggtgaa
     1441 actctttgat tatttcttta ttctcagata ctatttttgt aattttttct tttacttctt
     1501 tctttacttt tctatttata atccacatgc ttatttttaa ttttacaatt ttaaatatag
     1561 atttttgaac agattttctt gattttgtaa tataaaatct atacaattta aaggctctat
     1621 cagaaatttt accatcttct aatagtttca aaacagctaa taatccctgt tggtctgctt
     1681 ctgcaatcat catacttata agtttattat ctggagtatt tagtattcct ttttctgagt
     1741 ctaccaactg ttcatttaaa tcatgtataa ctggttgtac ttcttgtgct ttttcattac
     1801 taagttttaa aatggcttct ttcaaaatta gtttatatgc ctctttatca gataataaag
     1861 gttctgactc ttgtacgtta ttttttaata atcttggcag taaaactgtt gccaatacta
     1921 aacttataag aataacttct gatgatataa ataaaacagt atctctcatt ggaaatacat
     1981 ctttatcagc caaataaaaa ggtatagata aggcagttgc tagtgtaaat gtaccatgaa
     2041 caccacaagt agcaactatt agtgagtatt tacatttaga aatactctct tttacaactt
     2101 cttcatcctt aaaacctaaa aaacctacaa aaaaattatt taaaggattc tttttaggtt
     2161 ttataaaaga attatgccat aaatataccc atataaatct tataacaaat aaaataagta
     2221 caattaaagt agaaataaaa gtcaattcca atgccatatt ttcattttta ctactaagtc
     2281 ctgtatatat acttggtaac aaaaaaccaa gcagtgtaaa gacaaatcca ttcaatacat
     2341 actccaaaac ataccaagta ttgtctgata ttatccttaa tttagtagtt gtattttgta
     2401 aatgctcttt ttcaattcca tgagctatcc ctgccattac aacagctagg attccagata
     2461 ctcctatttc ttctgctaca aaatatacaa aaagtggagt cattatttgt ataactatta
     2521 ccattggaat ttcttccaaa ttccacttgt gtaaactaag tcttattttt ataattatgt
     2581 atcctaaaat acttcctact attattcctc caaaagctgt aatcataaat tgaatccctg
     2641 cctcttctat tgaaaaaact cctgtaactg tggcaagtac tgcaacctta aatgctacta
     2701 ctccagcagc atcatttaat aaagattcac cttcaagtat actcatcata tttttaggaa
     2761 aatttaatcc ttgtgtaatt gattttactg ctactaaatc agttggagat attactgctg
     2821 ccaaagcaaa tgaaacagat aatggcatcc caggaataag aaaatgtata aagattccac
     2881 ctgcaaacac ggttattaaa actaaaccaa atgcaagaag caaaattggt tttctgagct
     2941 ctaatagctc ttttctcgat acattttgtc cttcactgaa tagtaatgga gctatgatac
     3001 atattacaaa tatttctgga ttaaatgaaa atgagaattt aaatggcaaa atagacaata
     3061 taatccctag tacaatttga tatattgcaa gaggaatatt actccacttt ttgctaaata
     3121 cagttgaaat cgttgtacaa accaataatc ccaacaatgt tactaaaatt gacataacta
     3181 cctctctttt caataataat attatagatt aaacttatat atcaactaac ttaatattaa
     3241 cagcatgaaa tcccatctta atcaaaaaaa ttttcagttt attctattat tcttattata
     3301 tacatcaaat ttaatttttg aaatatctat actagatgac atgcaacaaa atgatttctt
     3361 gatatttctt ttaaaactgg aatctctttt ttgcatattt ccttacaata agggcatctt
     3421 gtatgaaact tacatccact tggtggattt gttggagatg gtatgtctcc ttttaatata
     3481 attctatttt tcttaattgt agggtcttgt attggtactg cgctcataag cgcttttgta
     3541 tatggatgtt gagaatgtaa gtaaagttct cctttagttg caatttctat tatagaacct
     3601 agatacataa cacaaactct atgtgcaata tgatttacta cactcaaatc atgagatata
     3661 aataaatatg aaagtttata tttatcctgt aaatccataa gtaaatttat aatttgagat
     3721 tgaatagaaa catctagtgc agaaacaggt tcatcacaaa ctataaattc tggatttaat
     3781 gctaatgctc ttgctatacc tattctctgt ctttgacctc cagaaaactc acctggtttt
     3841 ctatttaaat ggtacttaga aagaccacaa ctttctacaa catttaatat attatctttt
     3901 atttcattct ttggcactaa attatgttct ataactgcct cggatattat ttgttccaca
     3961 tttaatcttg gatttaatga actatatggg tcttgaaata tcatttgcat tttgggtctt
     4021 aactttctaa gttcttcctt ctctaactta tatatatcta caccattaaa ttcaacttta
     4081 ccttcagttt tttcaattaa tctaagaatg gttcttcctg cagttgattt tccacatccc
     4141 gattctccaa ctatagccaa agtttctcct ttttttaaat caaaagaaat tccatctact
     4201 gcctttacac atttaatttc cttatcaaat aatccagatt taacttcaaa gtacttttta
     4261 agaccttcta cttttaataa actctcttct tttttcaatt atatctcctc ctttttatat
     4321 aaccaacatg caatactatg accactattc aattctatta aaggaggtat ctgagttcta
     4381 catttatcac atactttttc acatctatca ctaaaataac atgaatctgg catcccaatt
     4441 ggatttggta cttgtcctgg aatcgaatac aatcttttat ctttgttttt tccaagagca
     4501 ggctttgatt ttagaagtcc aatagtataa ggatgttttg gatttttaaa taattcaaca
     4561 acctctgcca cttctataat tttgccagca tacatcacta atactttgtc acacatttct
     4621 gcaactactc ccaaatcatg tgtaatcatc attatagatg tgtttaattt ttcttttata
     4681 tttttcatta tatctaaaat ctgagcttga atagtaacat ctaaagctgt tgttggttca
     4741 tcagctataa gtaattttgg attacatgat aaagccatag ctatcattat tcgttgtctc
     4801 attccacctg ataattcatg tggatatgaa ttatatattt cttcagctct tggtatttct
     4861 accagtttta tcatatcgat tacctttttc ttagcttctt cctttgataa atcttgatgt
     4921 atcataatac cttcaatgat ttgacttcca atagtaaacg ctgggtttaa agatgtcatt
     4981 ggttcttgaa aaatcattga tatctcattc cctcttattc ccataagttc atcttcattc
     5041 atctttaaaa tatctttgcc tcgaaagatt atttctccac cttctatttt tgatgttgga
     5101 agtaacttca tcaaagacat ggctgttaca gacttaccac atcctgattc tccaactatt
     5161 ccaatagttt caccttcatt tatattaaaa cttacttcat ttacactctt tacaatccct
     5221 ttatctgtat gaaaataaac ttttaaatct ttaacctcaa ttagtgcttt actcattatt
     5281 ttctcctctc agcaaaatta cttaagataa catacacctt ttgattgtat tttataaaaa
     5341 tttaaattac aacattttct tacattttat tatttttttc tattaattat aataatataa
     5401 tagttaattt ctatatatat tgatttaata atgattacta ttatacaata aaaaatatgt
     5461 gttaaatatt attttatgga ggttttataa gaatatgaaa tttaaaaaat tggcatcatt
     5521 aatcttagtt tcatcattaa tgcttacatt tacagcctgt gcttccaatg ataaagacaa
     5581 gtctagtgga agcaaatctg gtggaactgt tgtaatacct atggcaagtg acccagatat
     5641 aatcaatgga gcttttgcaa acgttaaaga agactctctt gcatcaaata tagtttatgc
     5701 tcctctttat acttatgaaa aaggaaattt agtaaattat ttagcagaaa aagtagattt
     5761 taaagatagt aaggaattaa ctataaaatt aaaatccaat ttaaaatggc atgatggaaa
     5821 gccaataact gctgaagatg tcttatttac atttaataca gttttagacg aaaaacaaaa
     5881 ttcaccatca agacaatact tattggtggg tgagaaacca gttaaagtag aaaaaattga
     5941 tgatttaaca gttaagatta ctttaccaac tgcaagtgaa tctttcttat atggtatatc
     6001 taaaatttct ccaataccaa aacatgtgtt tgaaggagaa tcaaatatag ctaagtcaga
     6061 aaaaaataat aatccagttg gttctggtgc attcaagttt aaggaatgga aaaaaggtga
     6121 aagcatagta tttgaaaaga atgcagatta ttttggtgga gaatctaagg cagattctat
     6181 agcgctaaaa ataattccta atgaagcatc tcaagaagca gctttaaata atggcgaaat
     6241 ttcacttatg aagacatctg ctgaaggata tgaaaaggca aaatcaaact caaatttaca
     6301 aacttatact tatagtgaag aaagattaaa ctacattgta tttaaccaaa atatatcaaa
     6361 catggctaac aaagaagtaa gacaagcctt atcatatgcc ttaaatagaa atgaaatgat
     6421 agaatcagca tatggaaaag aaggttctgt acctgctaaa tctatattag ttccagaagc
     6481 agacttctat acagaagaag gtgttgaagg atatgaccaa gatacaaata aggctaaaga
     6541 cttattggat aaaagtggtg ttaaaattga taaattaaaa ataggttata acacaggtag
     6601 atttgggcat aaaaactatg ccttagtagc tcaacaagag ttgaaaaaaa ttggtataga
     6661 agctgaaata gttccttatg aaagtaaggc attcttcaat atactattta gtaatagcac
     6721 tgaatgtgat atgtatgtaa atggttatgc ttggggatta gaaccaaacc catatagagg
     6781 tatgtttgaa actggtcaat attgcaacca aactaaatat tctaatgctg aaatagatgc
     6841 tttatgggaa aaaggattta ctgagttaaa caaggaaaaa cgtgaagaaa tatataagca
     6901 aatacaacag gatatatcta aggatgcgcc tatttacact atagattatg aacaaaattt
     6961 aatggcagct caaaaaaatc taaaaggaat aaaagatgct aaaccatctc ctgcaatatt
     7021 atttgaagat tggtctaaac tgtatgtaga ataattgatg taaaatttta tattattaat
     7081 tagaaaagga gatgtctaaa aataatattg ttttattatt ttaaaacgag acatctcttt
     7141 taattaggag aatttactta tgttaaaatt aatattgaat agagtaaaag ttttaatacc
     7201 tatgttaatc ttaatatcta tattatcatt tggactttta gaattagctc ctggtgaccc
     7261 agcagatgca tatataaatc ctttaatgtc ttcacaggat attgaaaata taagggttaa
     7321 tatggggctt gataaaccag catatataag atatttaaac tggttgaaaa acactttaag
     7381 tggaaactta ggtatttctt atataaacca tatgcccgtt acagaacaaa ttatggaaaa
     7441 aatgggaaat acatttattc ttatgggtac ttctttgata ttttcaatat tggtagccat
     7501 acctcttgga atatttttag ctgtaaataa aaattcaata actagtaaag tatcatctgt
     7561 ttttaattat ataggtgttt ctataccttc tttttggata ggtatgatac tcatttcaat
     7621 tttttcagtt aaacttaaca ttttcccatc aggaggtatg catactattg gaaatgatag
     7681 tattggagat ttagcaaaac atttagtttt gcctgtaata actttaggtc tatataatac
     7741 tgctattttt acaaattatg tagaagctag tgtaaatgaa caattaaaaa aacaatatgt
     7801 tattacagca agagcaaaag gattatcaga aaaagtcata ctatttaaac atgtcttgaa
     7861 aaattcactg acatcattgg ttacaatcct aggcatgagt atacaaaaat tagtcactgg
     7921 tgcatttgtt acagaagtag ttttctcttg gccaggtatg ggaagattaa tgattgattc
     7981 aattttttca agagattata ctgtaattat ggcaataact atgttatcag cactattttt
     8041 aattttaggt aatttagttg ctgatatact atacttatta attgacccta aaataaaatc
     8101 tagcaaagga ggattctagt tgtgtttaca agtatcttaa aaaaattaaa aaaagataaa
     8161 tcctttgctt ttgcatgtat tactcttagc ataataatca tattaattat agcttctttt
     8221 atattaaata tagactctaa tgcaattgat actacttcta aacttcaaga acctagctta
     8281 aagcatatct ttggtacaga cgaacttggt agagattact tctctagagc tctttatggt
     8341 ggaaggattt cacttagtgt tggtatttta tcaatgctta tttctgtagt atttggtact
     8401 gctgtaggtg ttattagtgg atatattgga ggtaagctag accaattctt gatgagatta
     8461 gtggatatgc ttatgagtat accaagtttc ttagttttga ttgtattaaa tacttatcta
     8521 acacctaaag tttccactat tatactaatt attggattct taagttggat ggaagtttca
     8581 agaattgtac gtggcgaaac attaaaaata aaggaaaatg aatactgtct agctgctaaa
     8641 gctactggta tcaaaactag aaatatacta ttaagacata tagttttaaa cttaaaagag
     8701 actattgtag ttgctggttc gttaaatatt gctaatgcta tcttaactga atctgctctt
     8761 agttttttag gtcttggaat ccaattgcct cttgcatcat ggggtaatat gcttcaagat
     8821 gctcaaagac atatttttga caagttatat ttagctgtat ttccaggatt acttatattt
     8881 ttaacagtca tgagtttgac tataataagc aaaaaatttt ctagtaatac ttaacaaatt
     8941 ttatatagaa aataaaaaca gtgattatct aaagatatac actgttttta tttttcgttt
     9001 aaaaaaatac atattttgta tattataact ttaaatacta ctctaccatg ttatgcaaag
     9061 cgtattattg ctctcaaaca tatagatgaa aaactaatag tttattataa taaaaattga
     9121 tttatttatt tgttatttta ataacatttt taagagttct ttttactaaa gaaatctata
     9181 ataaatttaa atacatgttg gtctacatgg ctataacgtt cttttttagg tctacataat
     9241 ataactttcc atgtaatagg atgattaaaa ggcttttcta taattttgct attttcaaaa
     9301 aaatcatgaa ctggtgatgg taaaattgtt ataaaatcag aatttgtggt tgatagcaac
     9361 aaaaaatccc atgaaccaga cattatatat ctttttaact taacattttc atcagtaaat
     9421 ttttgcatta gcttatgatg tatcataaaa gtaggattaa atattgcaag taactgctca
     9481 ttcaaatcgt tccaatctat cttatccttc ttagcaagtg gatgatttat atttaaaaat
     9541 gctgtaagtt catcttcttg aagcacatgt tcagttacta cacttttatc aattttatgt
     9601 ggatgtaaca atactgcata atctaattcc tgtaagataa gcattctatt taagtcatat
     9661 gcacccttct ctactatatc aaattctata tctggattat ttgcaactaa ctgtgcaact
     9721 acatctgaaa atgctattcc aagtataagt ggaggtattc ctattctaac ttttccttta
     9781 aattgaactg aatcttctct taaatcttcc atcatatttt tgtattcatt tatgatatgt
     9841 tctgcattta cataaaatct ttctcctgct ggtgttaacc catttaacct gcctttatac
     9901 ctttcaaata aatatacatc ttcactttct tcaaaatttt ttataatttg acttaatgct
     9961 ggttgagata tgtgaagtgt cttagatgct attgataaat taaaaccaga tttcactatt
    10021 tcaacaaaat atttcaactg ttttatatcc attttaaacc cccttcccca aaagtataat
    10081 ttagattata ttttttcttc taatgatatt ttataggaaa atcaacataa tttcattaat
    10141 attttaacaa aatatttttc taaatctact ataaattttt atcctataaa tttttcttat
    10201 acactatata aaaaattaga cttagacaaa acgctttttt cgccgtaatc tataattaga
    10261 aacaggaaaa cctaaagcat taggaataaa agtaattgaa atacttaaaa acaagcttgt
    10321 attaaaaaag tactttatta tagtgttccc taatttcttt attcagaaaa tttttaatta
    10381 tcattcaaga aaggtaacta ttagatatga aagatgtagt aatcgtatca gcagtcagaa
    10441 cacctatagg aagttttgga ggtgtattta aaaatacttc agctgttcaa cttggaacta
    10501 tcgctgttaa agaagcgata tcacgtgtaa gacttaattt atctgaaata gatgaagtaa
    10561 taattggaaa tgttcttcaa acagggcttg gacagaatgt tgctagacaa attgctataa
    10621 atgcaggtat accaaattct gttccaagct acacagtaaa taaattatgt ggttcagggc
    10681 ttaaaagtgt ccagctagct gcccaatcaa tcacatctgg tgaaaatgat gtggtaattg
    10741 caggtggtac tgaaaatatg agccaagctc cttatatcgt tccaactgct cgctttggta
    10801 gtaaaatggg tgacataacc atggtagata gtatgctaac agatggcctt attgatgctt
    10861 tcaatcagta tcatatggga ataactgcag aaaatattgc aactaaattt gaatttacta
    10921 gagaaatgca agataaattg gcattagaaa gtcaaaataa ggctgagaat gctataaaaa
    10981 acaaccgctt taaagaagaa atcgttccag tagatgtttt aatacgtcga ggaaaaatag
    11041 aaactattga taaagatgaa tatcctaaat taggtatgac atttgaaggt ttatctaaac
    11101 ttaaacctgc attcaaaaaa gatggtactg taacagctgg aaatgcctca ggtattaatg
    11161 atggtgcggc tatgttaata ctaatgagcc aacaaaaagc agacgaacta ggtattagac
    11221 cacttgctaa aataaaatcc tatgcttcag ctggtgttga acctgaagtc atgggtactg
    11281 gtccaatccc tgcaactaga aaagcactga aaaaagctgg acttagcatc aatgatatag
    11341 acttaataga agcaaatgaa gcgtttgctg cccaagcatt agctgttaaa aatgaacttc
    11401 aaatagattc atcaaagtta aatgttaatg gtggtgcaat agcattagga catccaatag
    11461 gagcaagtgg agctagaata cttgttacct taatttatga aatgcaaaaa cgtaaagttg
    11521 aaactggact tgcaacactt tgtattggtg gtggtcaagg aatatcaatg gtggtttcac
    11581 gataggagga aatatgaata aaatagttag cattgatgaa gctctatctc atgtaaaaga
    11641 tggagataca ataatggttg gtggattcat ggccaatggt tcaccagaaa atttaattga
    11701 ttatttatgt agtaaaaata taaaagattt gacactaatt tgcaatgata ctggctttat
    11761 tgacaaagga gttggcaaaa tggttgtaaa taagcaattt aaaaagataa ttgcttctca
    11821 tgtaggatta aataaagaaa ctggaagaca aatgaataac aatgaaacag atgttgagtt
    11881 agttcctcag ggaactcttg ctgaacaaat acgtgcagct ggttatggtc taggaggtat
    11941 actcacaccg actggtattg gtactcttgt tgaggaggga aagcaaaaaa ttgttgtcga
    12001 tagcaaagaa taccttcttg aaaaaccaat ttatgcagat gttgctcttc tatttgcatc
    12061 aaaggtcgat aaagcaggta atctagttta taaaggctct atgaacaatt ttaataattt
    12121 aatggcatct gctgccaaaa ttacaatagt tgaagcagat gaaatcgttg aaattggtga
    12181 tattgaccca aatgaagtta atacaccagg tatttttgtg aattacatcg ttgaaggagg
    12241 taatttataa tggataaatt agaaatgcaa gaatatattg caaatagagt atctaaagaa
    12301 ttaaaagacg gagccgttgt aaaccttgga ataggtctac caaccaaagt agcaaattat
    12361 attccggata atgtaaacgt tatcttacaa tctgaaaatg gctttttagg tttaggttca
    12421 gccgaagatg gaaattcaag tgatgaaact attgtaaatg caggtggtca accagttact
    12481 atacttcctg gaggatgttt ctttgatagt gctacttctt ttggaataat cagaggaggt
    12541 catgttgata taactgttct tggcgcactt caggttgaca aatatggcaa tatagcaaac
    12601 tatatgattc caggtaagat ggttccaggt atgggtggag ctatggacct agtaactgga
    12661 gctaaaaaag ttattgtagc aatggaacat acttcaaaag gttctgcaaa aatattaaat
    12721 aattgtactc ttccacttac tgcaacaaat gctgtagatt tgatagttac tgaaatggga
    12781 gttatggaag taacatcaga tggaatttta cttaaagaaa taaatccagc tttcacatta
    12841 gatgatgtta tttctgctac tgaagctcct ttaatattgt cagattcatt aaatggaaaa
    12901 atatctgttg tttaaaataa ttaaaactag aaaataaaaa tctcttagac gtattacata
    12961 taaatttgta ttgcttaaaa tattaatata aaaataaaat aaaattggag gaaatgaaaa
    13021 tggttaaaga taaagttgta ttcgtaacag gagctgcaag tggaataggt aaacaaatag
    13081 ctgaatcgtt cttaaaaaat ggtgctaaag taatgttctc tgatataaat caagaagctt
    13141 taaataatac cataacagag ttacaaaaaa aaggttatga ttgcatgagt gtaaagtgtg
    13201 atgtaactaa ggaagaagaa attaaccacg ctatagacaa aactgttgaa aagtatggca
    13261 gattagatat attaataaac aatgctggac ttcaacatgt ttctatgata gaagatttcc
    13321 caactgataa atttgaattt atgataaaaa taatgctgac agcacctttt atagctacta
    13381 aaaaagcatt tcctataatg aaaaaacaag gctttggtcg tataataaat atggcctcaa
    13441 tcaatggtgt aataggattt gctggaaagg ctgcttataa ctcagcaaaa catggactta
    13501 ttggactaac aaaagttgct gctcttgaag ctgccgattc tggtataaca gttaatgctt
    13561 tatgccctgg atatgtagat actccacttg tcagaggtca gttcaatgac ctttcaaaaa
    13621 ctcgtaatat accattggaa aatgtcttag aggaagtttt atacccactt gtaccacaaa
    13681 aacgcctatt agatgttcaa gaaattgccg actatgctat gttcttagca agtgataatg
    13741 ctaagggtat tacaggacaa gcttgcttac tagatggagg atatactgca caatagttat
    13801 tatatttagg gcttgaagaa agtattcttc aggtccttct actaaggagg gatatttatg
    13861 agtattatcg cgccaattgg tataattatt ggtatcatag ctattatata tttttcagtt
    13921 aaagaaattc atataactat agctgctcca atagcaactt taatagttgt tattttaaat
    13981 aaaatggatg ttgtaacgtc aatgctaggt gctgacaaaa acaattatat gggtgcactt
    14041 ggaaactata taatgagtta ttttgcaata ttcttattag gctcaatact tgctaaattt
    14101 atggaagaaa gtggagctac tgtatcaata gctgatttta ttttaaataa atttggctct
    14161 aatcatcctt atagagtttt agttgctata tttatagtaa gttttatatt aacgtatggt
    14221 ggtataagct tatttgtagt tatgtttgcg gtcattccac ttgcaagaac tctatttaaa
    14281 aaacttgata tttcttggaa ccttattcag ataccacttt ggcttggtat tgcaacaatt
    14341 actatgacta taattcctgg aacaccagcc attcaaaatg ttatacctat tcaatatcta
    14401 aatacgtctc ttactgcagc tactatacca agtattgtag gtagtatagg ttgtgctaca
    14461 tttggacttg tctatatgaa atatgctcta aacaaaagta ttagaaaagg tgaaacttat
    14521 gcaacttaca cttcagaatt agaagaagaa tctttagata gagaattacc aggatttttt
    14581 gcaagtattt ttcctctatt agcactcgta attatagcta taactggaag tacttttggt
    14641 tcagaattta tgaaaaaaaa tgtaatttac atagctttaa tagttgcaat tcttttatct
    14701 gcttttttat tccataaatt tctatcatct aagatacaga cattgagcat aggtgctagt
    14761 ggttctatag gtcctatatt tgctacatct tctgcagttg catttggagc agtaataatg
    14821 gctgcacctg gttttgatgt atttagcaaa cttataatgt caataccagg tagtccactt
    14881 ataagtctta ctgttttgac ttcaacaatg tcagcaataa cagggtcctc ttctggtgca
    14941 ttaggaatag taatgccaaa ctttgcagat tattatttaa gtactggtct aaatccagaa
    15001 ttaattcacc gtgttgctac aatagcttca aatatactaa ctatagttcc acaaagtggt
    15061 gtttttctta cattcttaag cttatctaag ttaacacata aaactggatt taaagaaact
    15121 ttcattgtag ttgcagttgg ttcactaata gcagaaatta ttgtaattac attaggatta
    15181 ctaatgtatt aatataaaac aagttaaaat tcataatatg aaaggtggtg tctcaaagtg
    15241 aactttttac ttaatgagac actcttttta tatgaaataa catatgccta tcatttaaac
    15301 aataaaaaag gccttatctc tattttgaga cagacccttt ttatttctta aagatttaaa
    15361 taattataat ttgttgctaa tacgaaagca tctactgaat aaatttaacc aaataaaaaa
    15421 aaatttatca taactataaa tttacgttat ggaattatta taaaaatatt attttctcta
    15481 actaagtaat tccatactat acaggctttt aatacaaatt gtcaaacaca ctgaaatata
    15541 cctatttatt ccatatatat cttttttaca tatctttaca gtaaaaaaag tcttaatctt
    15601 atgttagtat agattcacgg gtaaccccct acactaaagg ttacaaatca gtaacatttt
    15661 tagaattttt agattaagag gtgtttaatg atgagaagaa atataccaac aaaattaaaa
    15721 actatattag ctttaggagt gttaacttta gcaacagctt caagtgctgt tactgcaagt
    15781 gcttcatcac ttgaaaataa tgtaaatata agtaacaaaa gtttagtata tagtaatact
    15841 aaatacaagt tttctgcaaa accaaattgt tctgtaaaac cagaacttaa gcctgataaa
    15901 gataactctt gtaaggataa gaatcataat gacaagaatt gcaacaacac taataaacct
    15961 gaggacaaca ataattcaga ctctactaat aagcctgata acaataaacc tgagtctaat
    16021 aaacctgaag acaacaataa ttcaggctct actaataaac ctaataataa taaacctgag
    16081 tctaataaac ctgaagacaa caataattca ggctctactg ataaacctga taacaataaa
    16141 cctgagtcta ataaacctga agacaacaat aacaataatt cagactctac taacaaacct
    16201 gatgataata acaactcagg ctctacaagt gaaagttttt cagcttacca aaaagaagtt
    16261 gttgacttag taaatataga aagagctaaa gctggattaa atcctcttac tcttgattct
    16321 tctatatcaa atgttgctac aaaaaaatct caagatatga ttgataacaa ctatttttca
    16381 cacaattctc caacttatgg ttctccattt gacatgttga aaaaatttgg aataagctat
    16441 aagacagcag gtgaaaatat agctatgggt caaaaaactc ctaaagaagt tgtaaacgca
    16501 tggatgaatt ctgaaggtca cagaaaaaat ataatgaatc caaatttcag taaaataggt
    16561 gttggagtag cacaaaaaag tggtggttca atttattgga cacaaatctt tgtaggataa
    16621 aatactcttt ttccatacat atcaaaagag tatctctaag tgataaaaaa cacaaatgag
    16681 atactctttt gtatctattt taaaattatc aaatccaaat atacatacta taaatattat
    16741 ttgttctctt aattttagtg tgtagaacaa tatataaaaa gtattggcaa gatgaaaatg
    16801 gaaaacttaa aaaagatatt taataggtaa aaacaaaatc ttaatatctt cataaaaaaa
    16861 ggctgtctca aaatagagat aaggcctttt tcattgttga aatgattaaa atatatttga
    16921 tttcatacaa aaagagtgcc tcatgaacta aaaagctcac tttgagacac tctcttttat
    16981 caatttatat aagcattata atactttaat attattcagc taattttttg tatccttcat
    17041 atctttcttt agcatcagct tcagctttag caaataatcc atcagcttct tctgggaatt
    17101 gtttagctat agcagaatat cttacttgtg caagtatgaa atctttgaag cttgcagttg
    17161 gttcttttga atctaaagtg aatgggtttt taccttcagc ttttacttct ggattgaatc
    17221 tgtataaatg ccagtatccg caagcaacag cttgtgcttc gttagctaca gttcttccca
    17281 taccttcttt taatccatgg tttatacatg gagcataagc tattattaga gatggcccat
    17341 catgtttttc agcttctata acggctttga taaattggtt tttatcagca cccatagcaa
    17401 cttgagctac atatacgttt ccatatgtca tagccatcat tcctaaatct ttctttctag
    17461 attttttacc tgaagcagca aacttagcca tagcagcagc tggagtagct ttagaagctt
    17521 gacctcctgt atttgaatat acttctgtat caaatacaag tacgtttaca tcttcaccag
    17581 atgcaagaac atggtctaat ccaccgtaac cgatatcata tgcccaaccg tctccaccta
    17641 gtatccattg agatctctta actagataat cttttctatc ttttatagct tttactaact
    17701 ctttagcttt ttcatctgta caatcacaag ctggtttttc taataattca acaaccttag
    17761 cacttgctac tttagaagct tctccatcat ttctagaatc taaccactct gtaaatactg
    17821 ctttagcatc ttcacagata cccatagaaa ctaactctgt catagcatct actattttat
    17881 ttcttatttg cttaacagct gtgtacatac caaatccata ttcagcatta tcctcgaata
    17941 aagagtttgc ccaagatgga cctttacctt catggttaca agtataagga attgatggtg
    18001 cagaagctcc ccatatagaa gaacatccag tagcattagc tatcatcatt ctatctccat
    18061 ataattgtgt aactacttta atgtatgcag tttctccaca tccagcacat gctcctgaaa
    18121 actccattaa tggttgtcta aattgacttc ctttaacagt gtttacaggc ataacatcac
    18181 cttttggagc tacctcatca ggatttactg caaatgccca attatctaac tctgtatcaa
    18241 gttgagtatc tattggcttc ataactaaag ctttttcttt agctggacat atgtcagcac
    18301 agtttccaca tcctgtacag tcaagtggac taagttgcat tctatatttt aatccttcta
    18361 atcctttacc taatgctttt ttagcttcaa atccttctgg agcattagct aattcttctt
    18421 cagtaactaa tactggtctt atacatgaat gaggacatat aaaagaacat tggttacatt
    18481 gaatacagtt atctattatc cattcaggaa catcaacagc tataccacgt ttttcataag
    18541 ctgcagtacc acaagggaat gttccatctt ctataccatt gaatgtactt actggtaagt
    18601 tgtttccttc ttgtgcagtc attggtctta gtatattttt tataaattct ggttctttaa
    18661 cttctccttt atctgcatca acagcatttt cccaagaagc tggaacttca actttaacta
    18721 aagcatttat tcctgcatca acagcagcat agttcatgtt aactattttt tcaccttttt
    18781 taccataagc tttaactata gaatctttta agtatttaac agcatcttct tctggtatta
    18841 tttcagctaa tttaaagaat gcagattgca ttatcatatt tattctgttt ccaagaccta
    18901 tttcttgtcc tagtttaaca gcgttaactg tatagaattt tatatcattt ttagctatat
    18961 attgcttcat atgagctggt aaatgttctt caagtcctgc ttggtcccat atagtgttaa
    19021 gtacaaatgt accacctttt ttaagacctt ttaataaatc atattgataa acatatgatt
    19081 gtttatgaca ggcaatataa tcagcttcat ctattaaata agtagctctt attggagtat
    19141 caccaaatct taagtgagac atagttatac caccagattt tttagagtca taatcaaagt
    19201 aagcttgagc atatttttca gtatggtcac caattatttt gatagcttgt ttattagctc
    19261 caacagtacc gtcagaacct aatccccaga acttacatct tatagttcct ttagaagcta
    19321 tttttattgg ctcagatgga gttaaagaag tattagttac atcatcaact atacctactg
    19381 taaatccatt tttaggttgt tctgaaacta agttatcaaa aacagttttt atatctgaag
    19441 gagtagtatc ttttgaacct aatccgtatc ttccacctat tatcatagga gcattttctt
    19501 ttccatagaa tacatcacgt acatctaagt ataatggttc accagttgaa cctggctctt
    19561 tagttctatc aagtacacat attctttcaa cagtagatgg catagcatct aagaaatgtt
    19621 tcattgagaa tggtctatat aaatgaactt taactaaacc atatttttct cccttagcat
    19681 ttaagtaatc tatagtttct tctattgttt ctgttactga acccatagct attaatacgt
    19741 atttagcatc ttctgctcca tagtaatcaa ataaactatg ttttctacct gttaaattac
    19801 tcattttttc catgtatttt tcaactatac ctactatatt ttgatagtat ttattagaag
    19861 cttctctagt ttggaaatat atatctgggt tttgagcagt accacgagca actggatgat
    19921 ttggagataa agcattatct ctaaatgctt gaactgcttc aaagtttaat aaacttgcat
    19981 aatcttcatt ttctagtaat tcaacttttt ggatttcatg tgaagttctg aatccatcaa
    20041 agaaatgtat aaatggtaat ctaccttcta ttgcagctaa atgtgcaaca ggtgctatat
    20101 cagctacttc ttgaactgaa ccagaagcta ataatacaca tccagtttgt ctagcagcca
    20161 taacgtcttg gtgatcccca aatattgata acgcttgaga tgctaaagca cgagcactta
    20221 catggaatac tcctggtaat aactctcctg caactttata catgttaggt atcattaata
    20281 ataaaccttg agatgctgta aaagtagaag ttaaagctcc tccttgtaaa gaaccgtgga
    20341 atgttcctga tgcacctgct tctgactgca tttcaacaac attaactgtt tgtccaaata
    20401 tattttttct tccttgtgat gcccactcat caactacttc agccatagtt gaagatggtg
    20461 tgattggata tatagctgct acatctgtaa acgcataggc aacatgagct gcagctgtat
    20521 ttccatcaag tgttttcata aacttagcca taatatgtat cctccttgat agctacaatt
    20581 gtacttgttt ataacaagtc tattttttta tatttacata taatttacac aacaaaacta
    20641 taaacacaca tatagtcgcg caaatactct atcttctaat ataatactac agattagata
    20701 aaattccttt gaaaattgta aattaattac atatttaagt agattttttt taaaattaaa
    20761 tatgttaagt ttttttcata attttgtata caatatataa taaattaagt tagatttttc
    20821 aaactttttt atctatttgt tcatattagt ataaaaagta aaatgcttat ccttattaca
    20881 tgtaaatttt tatatatata attttaccat attacatcat atttttgtaa gtttttatta
    20941 cattttttat aatacccctt tattttataa attaatctaa tcgattaaat ttatcctata
    21001 gaaatttatt acatttaaaa atatgctagc aaataaaata tctactagca taaagtctat
    21061 ttataatatt aatcaactat taattctact aaatctccat ttttaacgcc tgctgcattt
    21121 ccctcttcca tatcaacatg catttctaga ttaaagctgt cactagctct tactaataca
    21181 ttttcaaata ctaatgctct tggtccagat gttttaactt ttactatttg cttatcagtt
    21241 acaccaaatt tagcagcatc ttcattgctc atatgtatat gtctagaagc aactataact
    21301 ccttctttca tttcaacttc tccagcaggt cctactaatt taacacctgg agttccagct
    21361 atatcaccag attcttttat tggtgctttt actcctaatg ggaaaccatc tgctaaagat
    21421 atttcaactt gagtatgagc tctagctggt cctagtactc taactccttt taaagttcct
    21481 tttggtccta ctaaatccac tttttcttca caggcatatt gccctggttg agataatggt
    21541 ttaaatttag ttaactcatg acctgcccca aataatacgt ctatatcagc ttgactcaaa
    21601 tgaacatgtt tattagataa tgctattggt aatttcattg aaattccctc cttttaatta
    21661 tttaaattat tgcaatacaa ttatacataa tattacctac aaaatcaaat tatattgaat
    21721 caatatatat ctttaaattt ttatatatta tatctttaaa ttcttgatta tctatataag
    21781 atacatcatc tgtattgttt aaatatatat tgtgtaaaag tttagtattt atactcttaa
    21841 agaaaaaatc catcacaatc tgtccacctt taaactgtga atcatatgat ttactccccc
    21901 ccactgcaat atacattcct atccgtttct tacttctatc aattgaaggt ttatttaata
    21961 catatttact tgcatatata gcttgagttc tatcaacaac agtctttaat ttagctgata
    22021 ttgaatcaaa atgtacagga cttattacta tagttccttt tgaatcatca aacattttat
    22081 ataatggctt catatcatca ttaaacttgc aataccctgt tttttcacaa aatccacatg
    22141 ctgtgcaata ttcaatatcc atattgtaga tattaaatat tttacaactt aatccacact
    22201 cttctagcat agcttttact tcatttgcta taaaactgca atttttatta attcttggac
    22261 ttccatttat tattataatc tctggacttt taagtccttt tttatcgttt gaatccataa
    22321 tcaatctacc tatcctttaa cataactatt aaaatatcat catcataatt atcttttgat
    22381 gagaagttct ttaaatccaa ttttagattt tctactatta actgttgatt taatctaaaa
    22441 ttttctttta gaaagttttc taatcggttt ataccatact cttcttttga tgaatttttt
    22501 atctctaaaa ttccatcagt gtacatacat accattgcat aatcttccat tgaaagagta
    22561 ttattttcat aagtagcatc ttccattatt ccaataggta tgcccttttt acaatttaaa
    22621 ttattttcta ttgtgccatc tttctttaca actacaggac tatagtgacc tgcattagac
    22681 acagtaatca tattttcttt agtatctata atacctatca aacaagttgt aaatactccc
    22741 atcttgtcaa attcatcata taacatccta tttaaatttg tcattatttc tcttggtgta
    22801 ttgtattgat tgcataatac tttaaaagca ccttttatca ttgcaacaac ataatttgat
    22861 accattccat gtcccattac atcagcaaca atataaacta tatgttcgtc atccactttt
    22921 gtagcataat aaaaatctcc acctactacc cttgctggtt tatggtaaaa ataaagttct
    22981 ttctcatcat tacaatccat tttaccttta tccataataa gctgttgttg tttatttaat
    23041 atgttcaact cgttttcaag aactttgtgt tttacttcct tttcattatg ttcatataat
    23101 tgcataccaa cagaaacttg tttggacaat atactaagaa tatttaaatc atcactagta
    23161 tagtttttgc tatttgcaca aactatacat cctatagtat catttttatc ctgaagtttg
    23221 taatatatat aactttccaa atttattccc ttttttgagc atggttttaa attatttaga
    23281 taccccccca atgactcttt ctttaaaaac atatcaatca taggatataa atttgttttc
    23341 tttttttgct caacattata acaactaact atagcatcct tattatgatg actatttata
    23401 attattaaag cttctttact attagtaata ttacacgctt gtttacttaa attttccaaa
    23461 aagccatcaa tactcttatt aaggtatagt tttttagtag cttcatttat ggcacttatt
    23521 gagcctctta gtttatcaat taaaatttgt acattattat ttttattagt tatttctatt
    23581 gataaactta agagtgatgc aacagatgat ataaaatcta tatcttgttc tgttatataa
    23641 tcatcctctt ttaaaaaaca agtcataaat ccaacaacta cgttatttat tataaaagga
    23701 aaaactattc tcccaatata accttcagct tttgctaaat ctcgttcacc ttctgctcta
    23761 gaatcttcaa atacattttc cacatatatt atcttttttt catttacagc ctcatgtata
    23821 tactctggat atgtgtcaaa atcaattttt gcacctttaa gactatttat tggaaaaatt
    23881 tgaggtacat attctaaggt ttgcgaacat actaagtagg catatttaga atcattttta
    23941 taaaatagat tcacacatgc ctttgtaggg tgaacaactt ctaacatttt ttctattatg
    24001 tcatctttta tattaaaaaa atctgtagat tcagtcacca tagcggatat ttccactaaa
    24061 ttcttcattt tataactgcc attagtcata ctcaatttct ccccctatat attaaactat
    24121 ttattagtat tttaacatac attctttata gtaaaaacaa aaacaacgac aaaactagca
    24181 actaatatcc agttaaatcc tgtcaataat cctataagaa gtaatgtaat taatgcattt
    24241 agacctgttc tccctttttc atccataaaa gttattttag agatgtcgat attatttttc
    24301 acattattta tatgctcttt cacttgttct tccatatttc ttttatatag tatataaact
    24361 acaccaacta aaaacactcc tatacctaaa accatgttta aattaaaagc taccataagc
    24421 aatattgaac caaaagctaa ctttaaaagc ttaaaaaata cactatctat ctttagagtt
    24481 atatttctga tttctttaca ttcatctctt aaagaatatc cacttgaatc taagttatta
    24541 atctttgttt ttacaatttc agaataaaaa agctttatta tcccatttaa cattttcatc
    24601 actcctaaat attttacata tatttgtaag ttttacaatt ataatatttt ttatacttgg
    24661 taataataaa aaataacaaa tattttatta tttagtattt attgtaaata agttattgaa
    24721 gcttgattag ttaagtatag atttttaata aatattttta taatttagaa ggaagtggtt
    24781 ttgtgcaaat agaacaactc gatttagaaa cgagaaataa aatatactgc tatactaaaa
    24841 aaattcttag aaaatatcaa aaaggcataa catctggaaa attaacagca gataaatttg
    24901 cagataatat attgtctcaa gattttatca gtagtatact taatgaaaaa atagtcaatg
    24961 agacaaactt taagatatct tatagaaact atatagaaac tttaataaat attcaaaatg
    25021 aaaatttatc taacttaaga aaaaaatcta ctaaaactgc aaaatgtttc aatatctctc
    25081 aaataaccca attaaaaaac ttactaagta atactggtta taatttatta attccatata
    25141 aatacttaac tgctagagat atagaaggaa tagttactct tattaatact gggtctattg
    25201 aacttggaaa tgagagaatc tacaattata tatcaaaagt ataataattt aaacctatta
    25261 taaaaaggca atttatttaa taaaaaatat ttttaatatt aaataaattg cctttttaat
    25321 tttggattaa atactgctat ccaagtgctt tttctagttt agataaatgt tgtattggat
    25381 aatattttag tagctcttta aattgttcta ctgataaacc ttctgttgtt gtatatattc
    25441 ttattttttc atctaagtca ctattaataa atttgttttt taaatcctca aaatttacac
    25501 tactcatttt acatcactcc ttatgtaaca tattcatttg tat
//
LOCUS       DAYAOO010000056        24984 bp    DNA     linear   BCT 12-OCT-2024
DEFINITION  TPA_asm: Clostridioides difficile isolate ST8-SSI-h139-18
            SAMN40601845-rid21577343.denovo.056, whole genome shotgun sequence.
ACCESSION   DAYAOO010000056 DAYAOO010000000
VERSION     DAYAOO010000056.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN40601845
            Sequence Read Archive: SRR28438827
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 24984)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 24984)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-MAY-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-MAY-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002157583.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002157583.1
            Genome Coverage       :: 163x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/11/2024 16:19:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 4,038
            CDSs (total)                      :: 3,963
            Genes (coding)                    :: 3,930
            CDSs (with protein)               :: 3,930
            Genes (RNA)                       :: 75
            rRNAs                             :: 6, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 60
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 33
            CDSs (without protein)            :: 33
            Pseudo Genes (ambiguous residues) :: 0 of 33
            Pseudo Genes (frameshifted)       :: 7 of 33
            Pseudo Genes (incomplete)         :: 25 of 33
            Pseudo Genes (internal stop)      :: 11 of 33
            Pseudo Genes (multiple problems)  :: 8 of 33
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..24984
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN40601845-rid21577343.denovo.056"
                     /isolate="ST8-SSI-h139-18"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Denmark"
                     /collection_date="2018"
                     /collected_by="Statens Serum Institute"
     gene            complement(48..656)
                     /locus_tag="ACGI5H_002512"
     CDS             complement(48..656)
                     /locus_tag="ACGI5H_002512"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427435.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-3-methyladenine glycosylase"
                     /protein_id="HFG9698212.1"
                     /translation="MEKDFFRKNGIDLAKSILGKYLIRKYENKVIVTKIIETEAYMGV
                     NDKGAHVYGNKKTDRTKPLYLDGGHIYVYLIYGMYNCLNLSANIENVPECVLIRGVEP
                     ITSLDEISMNRYNKAYTELSKYQVKNITNGPGKLCKALKIDRSLNSKSIMGEELYISD
                     FYYDDKGKKVFSKDELDIKTSKRINIDYAEEAKDFLWRFYIE"
     gene            complement(765..3503)
                     /locus_tag="ACGI5H_002513"
     CDS             complement(765..3503)
                     /locus_tag="ACGI5H_002513"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896425.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HFG9698213.1"
                     /translation="MESKGTLSKNKVYILANGLFLVIALLNINLYTVSINMYRIILLW
                     IFGYSIVYISSFKTDEFINILKVGCLVLVFVSILGVVNLKIQKFQIVLLNLSIINMST
                     FIYLTISKVKKLRISPILIFYSAFVILDYFIRNIFSDINWNMIIILINICISMFNLLY
                     LLNKLDSNIEHYKLIKDLTYFVFFTTIICFVAISKINIVDSDRLIGVIYLLLCNHTYY
                     VYVYSLNNRVVYPYYELDSINKKLSKKSEQLGKINLAIEKDMIIQRTLKNYIDQRKEL
                     LRQALDTIPNVWIVTDYDFNISYTNNKFKDEFSKDMNNYYKILTFIKEDEKVAEKLKK
                     FDNDISIIDKLVELNDKIYLLSLSNNKDESNYLISLNDITNEIKIDEEIRNINKDYEN
                     IILNIPSPILVRSAEGGIKKNKVISINKKYEKSFKCVSSDLVDMTLEQYFETFNIDFF
                     DNREFKRLNLTQEKKAEIVSYNDTANCIVNFVMSDSEGEEHVEEVRVGDYWSDNKLFK
                     LLTFRDITKEINILRTVNEQKIIYEKLLDVIPEAIFLEDLSTSRVLYTNRAFRELFGI
                     SSDVLGVTTQKYRNILVKKYINNLNIGEREKSIHIVNENNHIKEVKMISRTLYFGQKR
                     SRVRIIKDLSVQRESERLKKALIKQRQYDQMKMEFYANISHELKTPLNNIYSSVQLIE
                     NLYKKGKIIDFQDILKEHIKITKQNMFRLLRLIDNIINISQVKSDIYKIKAVNFDIID
                     ITERIVTSISSYAKSKGIDLIFDTDEETVMVGLDPESIERIILNILSNAIKFTLEGGE
                     ILVGIYKKDETVEIIIKDTGVGIDKEKLKDIFNRFKQIENSGISNEFGSGIGLCLTKS
                     LIEIQNGKIYIDSKVGEGTNVKVIFPIKEVVEEVYDNSNYNDNIEKFEIEFFDIYK"
     gene            complement(3651..4442)
                     /locus_tag="ACGI5H_002514"
     CDS             complement(3651..4442)
                     /locus_tag="ACGI5H_002514"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427438.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MetQ/NlpA family ABC transporter
                     substrate-binding protein"
                     /protein_id="HFG9698214.1"
                     /translation="MKLKKLLSVALVSAIAISAVGCSNKEDKKILVGASSNPHAKILE
                     VAKPLLKEKGYDLEVKIFDDYVLPNTALDEGSLDANFFQHIPFLEETVKEKGYKLTYT
                     SKVHIEPMGFYSEKVKSLDELKDGAVIAVPNDATNGARALKLLAKNKLIEVKDGELIT
                     KKDITKNPKNIVIKEMNAEQLPTVLKDVDGAVINSNYALTANLNPTKDAIVIESSDSP
                     YVNIIACRENNKDSDKIKALSEAMNSKEVKKFIQDEYKGSIVPAF"
     gene            complement(4478..5134)
                     /locus_tag="ACGI5H_002515"
     CDS             complement(4478..5134)
                     /locus_tag="ACGI5H_002515"
                     /EC_number="7.4.2.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419957.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0033232 - ABC-type D-methionine
                     transporter activity [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0048473 - D-methionine transmembrane
                     transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="methionine ABC transporter permease"
                     /protein_id="HFG9698215.1"
                     /translation="MNSLIDFLTTLFPNALLQTLYMVIVPTIVATILGFILAIILVVT
                     KPDGLKPNSTINSALGFIVNIFRSFPFMILIVAMIPITRLIVGTSIGETAAIVPITIG
                     AAPFIARIIESSLNEVDKGLIEAAKSFGATKRQIVFKVMIKEAMPSIVSGITLSIISI
                     LGYTAMAGAVGAGGLGNIALIYGYQRFDTAVMVYTVIALIILVQIIQGVGNLAYKKLK
                     "
     gene            complement(5127..6092)
                     /locus_tag="ACGI5H_002516"
     CDS             complement(5127..6092)
                     /locus_tag="ACGI5H_002516"
                     /EC_number="7.4.2.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419956.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0033232 - ABC-type D-methionine
                     transporter activity [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0048473 - D-methionine transmembrane
                     transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="methionine ABC transporter ATP-binding protein"
                     /protein_id="HFG9698216.1"
                     /translation="MISIKNVNKYYGKIQVLKDVSIEIESGEIFGIIGHSGAGKSTLL
                     RCINGLEEYQEGSVLVSDKEVKSLNEKQMRDLRKELGMIFQHFSLLERKTVFDNVALP
                     LECFGYSKAEIKKRVLELLEVVGISEKKNDKPRNLSGGQKQRVAIARALALNPQVLLC
                     DEATSALDPNTTKSILSLLEDINKKLGITIIVVTHQMEVIKQICGRVAIMENGEVLEV
                     GDTEEIFLRNTKGLRKLIGEESIILPKGTNIKILFPKDISNEAIITTMARELNIDVSI
                     IFGKLEQFKDDILGSLIINISDKSGEQVKQYLTSKGIRWEEMINE"
     regulatory      complement(6198..6304)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00162"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="SAM riboswitch class I; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="S-adenosylmethionine"
                     /db_xref="RFAM:RF00162"
     gene            complement(6594..7538)
                     /locus_tag="ACGI5H_002517"
     CDS             complement(6594..7538)
                     /locus_tag="ACGI5H_002517"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434114.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HFG9698217.1"
                     /translation="MSRAERLIELMITINAKRSFTAGELAEEFSVSKRTILRDLQVLE
                     SIGFPLYSKVGAAGGYHVLKERILPPIAFSESEVKSIFFAYQSLEYYNDLPFEQETIS
                     VLKKFLNCIPNDIQYNIENIRRKFVFWTPDRHCSTPLLKELFNIVMNEFTIKIEYSSK
                     QKNSVRTIVPIGLYAMNGLWYCPAYCIKSESIKEFRVDRIVKILSIENLSSKKYKVLS
                     SIHDYLKNMEVGTDYHIKINLTDEGVKRCETEFLLARGLKILSKGGYIDMYIPKSTLN
                     WVAEYFLTFGKNATIIEPIELKHLIKSKVLELYNHHCI"
     gene            7649..8116
                     /locus_tag="ACGI5H_002518"
     CDS             7649..8116
                     /locus_tag="ACGI5H_002518"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896419.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF6194 family protein"
                     /protein_id="HFG9698218.1"
                     /translation="MENDTIKADDILNYCLSNLDDVVLMDSWGERAIYYNPNGVLKRG
                     VYVLTIKEKDSNNDKGSLVSRPNVYRVNIGLKKETFIEMFGYIPKRPGVGQIVDMDFD
                     FTKLDTIMPHPIYSWMGWICVLSPTEKTFENFKTLIGESYNFAKQKFKKRKNK"
     gene            complement(8286..8885)
                     /locus_tag="ACGI5H_002519"
     CDS             complement(8286..8885)
                     /locus_tag="ACGI5H_002519"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434118.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9698219.1"
                     /translation="MKLKRTLFVGLALVLAIGITACTKNNEKPSENTGKNPNESVNNN
                     EGYMNYYSTSYNDYIAGLNRYSIYDTPESINNQFKDKEYPGNEKYLSDVKAAYKDSRD
                     KIQSFVTSLKKDGKTEDTELKKMNDDLIAEGERLVKDIDKRIEKLDKVSDEDMKKGQN
                     DFIKLVHGTEDVGNDIGSGFRKMIKDMNDRLGITGNNKK"
     gene            9131..9727
                     /locus_tag="ACGI5H_002520"
     CDS             9131..9727
                     /locus_tag="ACGI5H_002520"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889314.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3793 family protein"
                     /protein_id="HFG9698220.1"
                     /translation="MSCCNSQFCCKNKIESSYIKWLLEVLGPVFLGSKPAEIINISFT
                     DVNREEKINDIYKYLYKCKKIDFIVIDKEKKGLKILFVNKKALSEKLKCKKTVNFLKF
                     LGYKQNTNVNAYLEHLVDKLKSDVFPDEIGIFLGYPLKDVIGFMGYSNYEVSMIKYWK
                     VYGDTKQSEDTYSKFLLHRKKMRKLLDYISVDKIVSCF"
     gene            complement(9825..10784)
                     /locus_tag="ACGI5H_002521"
     CDS             complement(9825..10784)
                     /locus_tag="ACGI5H_002521"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012816136.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NrtA/SsuA/CpmA family ABC transporter
                     substrate-binding protein"
                     /protein_id="HFG9698221.1"
                     /translation="MTSLIMVLVGTVGCSTTNDKKDEPAKKEASLPKEINLTYVKSPL
                     NVPSILEKKDDLFGKEFKKDNIKVNFHELTTGPEQTQALAAGELDFLHALGGTSAIIA
                     ASNGVGLKITNIYSRSPKGYMLITNNDNIKSIKDLKGKKIVGPKGTILHQLLIAALAK
                     EGYTIDDVEYVNMDIPSAASALESKSADVAMLAGPVALKTINSGAKMIVNGEGLVSGI
                     IVTAVSDDFAEKYPELVKRFMKVHEETLKYMNENKDEVMDVVSKEVGLSLDETKEMYS
                     WYDFSSKITDKDIKELEDTQEFLMSNGMQQKKINIKDMLYNQN"
     gene            complement(10818..11549)
                     /locus_tag="ACGI5H_002522"
     CDS             complement(10818..11549)
                     /locus_tag="ACGI5H_002522"
                     /EC_number="7.6.2.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424657.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HFG9698222.1"
                     /translation="MVRSGFLLENIYKKYLVDNKEHLVLDNISLNISSEEITVILGES
                     GCGKTTLLRILAGLENATSGNVYFFNNDKKCTPKVGMVFQESRLMPWLNVSENILLHT
                     EKDNRNKVDLDKYLKMMKLEKFKNSYPNELSGGMAHRVSIARALSFNPDILLMDEPFA
                     ALDYFTRRKMQKEVVNIHKNTKKGVVFVTHNIEEAMEIAKKIIVFSKNKRIKQFSVED
                     EYNRDLTKNYYINLKKEILRELGEF"
     gene            complement(11542..12312)
                     /locus_tag="ACGI5H_002523"
     CDS             complement(11542..12312)
                     /locus_tag="ACGI5H_002523"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421601.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HFG9698223.1"
                     /translation="MFEKIHKRLKGYYIFLIILILWKIVCVLGIWSSYILPPPEIVLD
                     TFIKMIYDGSIFLNVYASVRRILIGFLISSLMAIPLGVLFGANKKMYEYFKPLFEFMR
                     STPPLALVPMLILWFGIGEESKIIIIILASFFPIFLNTLKGIKNCDNKLIEVGKSFNL
                     SKKRIFYKIIIPNSMLDIVVGLSLGLGYSFRAIIGAELIAASSGLGYLISDGKDMSRT
                     DVVLVGIFVIGFLGILSDYLFSKIITKFSKGKQVDLNG"
     gene            complement(12397..13107)
                     /locus_tag="ACGI5H_002524"
     CDS             complement(12397..13107)
                     /locus_tag="ACGI5H_002524"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427471.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AIM24 family protein"
                     /protein_id="HFG9698224.1"
                     /translation="MFKFDVTNELMCIARGSGKFFAKKGAMVAFKGNFNFEKLLLGPS
                     NGGGLGRALLGHVQRSLTGEQMPIMVVEGEGEIYLAQNAYHVDVISIDPGDSIYVESE
                     NLLAFSEQLNYSVKLIGSGVISQKGLFTTHLVNKTGQNQDVAIITDGNPLILEGPCCV
                     DPDALVAWTGREPYPKVSKLSWKTFIGQTSGESYHMEFVEPGQIVIIQPSERLSGLKT
                     DSTPSDRMSSGGLRLGID"
     gene            complement(13287..13439)
                     /locus_tag="ACGI5H_002525"
     CDS             complement(13287..13439)
                     /locus_tag="ACGI5H_002525"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419945.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FeoB-associated Cys-rich membrane protein"
                     /protein_id="HFG9698225.1"
                     /translation="MATFIIAAIVVVLMALAVMYMVKNSKKNGSSCGCGCSGCSSSKS
                     CHSAKR"
     gene            complement(13465..15621)
                     /gene="feoB"
                     /locus_tag="ACGI5H_002526"
     CDS             complement(13465..15621)
                     /gene="feoB"
                     /locus_tag="ACGI5H_002526"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896412.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_function: GO:0015093 - ferrous iron transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0006826 - iron ion transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ferrous iron transport protein B"
                     /protein_id="HFG9698226.1"
                     /translation="MSIKIGLIGNPNCGKTTMFNGLTGSSQYVGNWPGVTVEKKGGKL
                     KGNKDVEIVDLPGIYSLSPYTLEEVVTRNFMLDDKPDAVINIVDASNIERNLYLTTQV
                     LELGIPTVIALNMMDIVNKNGDKINIKELSEVIGCPVVEVTAVKGQGIMEAAEKAVEL
                     ASSNNKLNFKLPFVDESKDAIEKIEKIIEEKTPYIDVETRWLAIKLFERDENVIQKLD
                     ISKTILNSIEEITRNCEDELDDDSESIITANRYEFISSIISSIIKKNRKGKETVSDKI
                     DKIVTNRILALPIFALIMWGVYYIAVSSLGTIATDWTNDVLFGEIIQGNVSNFLASLN
                     VAEWLQGLVVDGLIGGVGAVLGFVPQIMLLFLLLSILEDCGYMSRVAFIMDRIFRKFG
                     LSGKSFIPMLISSGCGVPGVMSTRTIENDRDRKMTIMLTTFIPCGAKIPIIALFAGAL
                     FGGASWVAPSMYFLGIAMIIICGIILKKTSLFAGEPSPFVMELPQYHIPSAKGVLIHM
                     WDRGKAFIIKAGTIIFVACGVIWFLQSFNWSLQMVDAGDSILASLGNIVAPIFAPLGF
                     GNWQSSVATVTGLVAKENVVGTFGVLFGISDATEQDPTLLASVASMFTVASAFAFMAF
                     NMLCAPCFAAIGAIKREMGSWKWTWITLGFQTLTAYIIALLINQVGSLVLGTGGSIAG
                     AIISIFIAVAVVFVVLTYSNKNMKKEKMGKLSYMKN"
     gene            complement(15721..15942)
                     /locus_tag="ACGI5H_002527"
     CDS             complement(15721..15942)
                     /locus_tag="ACGI5H_002527"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419941.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ferrous iron transport protein A"
                     /protein_id="HFG9698227.1"
                     /translation="MNRLKDIKCGETVKVKKLEGEGATRRRIMDMGITRGVNIFIRKV
                     APLGDPIEVTVRDYELSIRKSDAEKIIVE"
     gene            complement(15955..16167)
                     /locus_tag="ACGI5H_002528"
     CDS             complement(15955..16167)
                     /locus_tag="ACGI5H_002528"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419939.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ferrous iron transport protein A"
                     /protein_id="HFG9698228.1"
                     /translation="MMPLILSNTGEEVVIKKISGSDKTRTFLNSIGFVVGTNVKIVSK
                     IDGNLIIDVKDTRVALDKKMASRIII"
     gene            complement(16488..19385)
                     /locus_tag="ACGI5H_002529"
     CDS             complement(16488..19385)
                     /locus_tag="ACGI5H_002529"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434134.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EAL domain-containing protein"
                     /protein_id="HFG9698229.1"
                     /translation="MKAFKKHFLILSLIFLLIISCFNNILCFADESENSKKIRVGYCD
                     DYGIISSSKEHSYTGYGYDYLREISKYTRWEYEFVKGSWEECLDRLEKGEIDLLGPLQ
                     KNDERNKLFNFPKLSSGYEYSALYTKDSNNNMFYEDISSFKGMRVAVLRGNFHNTAFE
                     KYREENNFSVEYIYCNSIDELIESVNEKKADAFVCGSIINAKGMKIVSKFSVEPFYFA
                     TAKDKPNLVKELDYALKELKINDMYYELELYKKYFKREVNNSIAFTRQEMNFIKANPK
                     LTMVYDSEWSPVEYYDEESNSFKGISSDLMSIISKKCGIKFEYIKTKNYNESLDYIKS
                     GKATMLCGSINENDKVKRFNMKLTNPYINIPMIMVGKLDTNLNNDLNIALTSSYKSID
                     SYIEKSFENAKTTSYKSVESCLNAINEGKANLMILSSYQFDELLREGKSENLSVISVL
                     DTSYGMRIGVSNKTDPILVSILNKSIDKITEEELSDCIYSNTIDKPYKVPFGVIFKEY
                     SIQIISFVCILFLIAIKYIIYNKKKKEDYLRKIAYTDPLTGADSIDKFKINSNKLFAK
                     NNPEEYALFYIDVDKFKYINDMFGYDMGNDTLIHISNTIASELKEDEIFARVSADHFV
                     LLIKYKTDDDIKTRLNNIYNKVQILSNPKINYYKLILDCGIYKISKSDNDINTIMDRA
                     NTARKTIKGGHKNSFAFYDKEMHKKILKEKEIENSMVDALNNGEFIVYFQPKYSLSDY
                     QIIGAEALVRWDNPQKGLIPPIEFIPVFERNGFIVNIDFYVFEEVCKKIREWMDEGQK
                     VVPISVNLSRMHFVNSNFIEEFKLIVDKYKIPTRLIELELTETAVLDNIEGLLDTMNN
                     LKEKGFVISMDDFGTGYSSLNLLKELPVDILKLDRAFFTEKDESNNEKIVISNVIKMA
                     KELKMKVISEGVETISQVEFLKQIGCDMVQGYLFSKPMPVKEFEKIAFKKE"
     gene            complement(19712..20320)
                     /locus_tag="ACGI5H_002530"
     CDS             complement(19712..20320)
                     /locus_tag="ACGI5H_002530"
                     /EC_number="3.1.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434135.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005829 - cytosol [Evidence IEA];
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="dienelactone hydrolase family protein"
                     /protein_id="HFG9698230.1"
                     /translation="MVDNLIKYIHKSDVAIVVLHEIYGINSFIEDVCQKYYKYGYDVF
                     CPELLGEKRVFPYSKVQEAYDFFINNVGFDIYKKVEKLINDLKSEYKYVFVAGYSVGA
                     TIAWRCSEDSFCDGIICCYGSRIRDYMDVIPKCPTLLVFAKHDSFDVDSISYQLSRKQ
                     NIQIEILDANHGFIDRYSNNYSDIQTKVFTIKEKSFLSKYLA"
     gene            complement(20580..21125)
                     /locus_tag="ACGI5H_002531"
     CDS             complement(20580..21125)
                     /locus_tag="ACGI5H_002531"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012816134.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADH peroxidase"
                     /protein_id="HFG9698231.1"
                     /translation="MKKFVCTVCGYIHEGDAAPAQCPVCKVGADKFEEMKGEKNWADE
                     HRIGVAQGVDEEIIEGLRANFVGECTEVGMYLAMSRQADREGYPEVGEAYKRIALEEA
                     EHAAKFAELLGEVVVADTKENLRVRVDAEYGATDGKLKLAKKAKELGLDAIHDTVHEM
                     CKDEARHGKAFLGLLNRYFGK"
     gene            complement(21243..23066)
                     /locus_tag="ACGI5H_002532"
     CDS             complement(21243..23066)
                     /locus_tag="ACGI5H_002532"
                     /EC_number="7.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728676.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HFG9698232.1"
                     /translation="MNLSTGNQKVSRLKKKEKPKDFKKTFKRIFMYFKKDKKITRFIF
                     LLVIIDSIISTVIPYTIGKVVDIIDIDTYSKSIFLKGIIILLSFYIIEFSVKLSKGIC
                     TARLSQSIVKEMRSNLFLKFKNLPITFFDKSSTGDIMSRVTNDVDNISTGISNSLVQL
                     ITGILNILMTFIMMFVLSPILTFCSVILIPIVMFVSNFIAKRTRVFFKQQQVELGKLN
                     AHIEEMISNINVVKSFNYERKSVNDFKEVNDRILNISLKSQIYTSLLMPIMNVISNIG
                     FATICIIGGILASKDIITIGVIASFLSYVRQFTRPLNELANLFNTLLSAIAGCERVFE
                     IIDEQEEQEVHNMFKSEINDNKDGNLNSHFVKGEIELKDVSFSYDSKKKILDNINLKI
                     KAGTSNAIIGETGSGKTTIINLITNFYHIDEGSILLDGKDIYSINRNYLRTCFGVVPQ
                     EGYIFNDTVMENIRYGNLEATDEEVIYASKIANAHKFIVKMREGYSTVLSDRGEDLSE
                     GQKQLISIARAVLKNAPILILDEATSNIDIATEAKIQEAINNLTYGKTSIIIAHRLST
                     ISNCDNIIVLENGRIVESGNHKELIKLKGHYYRNILLTQGK"
     gene            complement(23079..24854)
                     /locus_tag="ACGI5H_002533"
     CDS             complement(23079..24854)
                     /locus_tag="ACGI5H_002533"
                     /EC_number="7.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902522.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HFG9698233.1"
                     /translation="MRYFKKYIKKYIVLFLTAVFFLTLEAFCDLAQPTIMAKIIDIGV
                     SNKNLDYILSTGAIMIGITFLGAIFAIIRSVISARVSQHFSYDLRQDVFEKINTYSLK
                     QIDKFGRASLITRITNDINQMQQFVNGMMRVFIKSPIMCIGSLIIAIKLNLKMSIIIL
                     IAVLIIFIIILLNMKIGYRLFKNVQESTDKVNSKLRQFLSGIKVVKLFCRYDYENQSF
                     EELNDELFKNSRKATTMMSFFRPTITIIINVSIIIILLIGRHLIYSGEIKIGIIVAYV
                     NYMTRILTSLIMISHVFNVFVRAKASYERISEVLVDENEEVIEREESLDVGEKDLKFV
                     NCDIIFENVDFSYNKNTDEKILKNVSFKIEEGQNIGVIGQTGSGKTSLVNLIQKLYII
                     DKGDIKIGGRSIYSISEESLRARIGVVFQNSSVFGKSILENVVMGNRDICKEDVVKSC
                     EIANANQFITKLENTYDEVLFQRGKNLSGGQRQRITIARAIAKKPQILILDDCFSAMD
                     INTETIIRKNIKEYISNLREKESKKCTVITISQKISSIIDCDKILVLDEGEVVGFATH
                     EDLLVSSPIYKKIFALQNLVSEDVN"
BASE COUNT         8226 a         4337 c         2446 g         9975 t
ORIGIN      
        1 cctataaaat accttcctat agatacatat cttacctata taaaaactta ttctatataa
       61 aaacgccata aaaaatcttt tgcttcttct gcataatcta tatttatacg tttactagtt
      121 tttatatcta actcatcttt actaaatact ttttttcctt tatcatcata ataaaaatca
      181 cttatatata attcttcacc cattatactc ttactattta gacttctatc tatttttaaa
      241 gctttgcaaa gttttcctgg tccgttagta atatttttta cttgatattt actcaactca
      301 gtgtaagctt tgttgtatct attcatagat atctcatcta aagaagttat aggctctacc
      361 cctcttatta atacacactc tggcacattt tctatatttg cagataaatt caagcaatta
      421 tacataccat aaattaaata aacatatata tgtccaccat ctaaatataa tggcttagtt
      481 ctatctgtct ttttattgcc atatacatgt gctcctttat catttacacc catgtatgct
      541 tctgtctcta tgattttggt aacaattact ttattttcat atttccttat tagatattta
      601 cctaatattg atttggctaa atcaattcca ttttttctaa aaaaatcctt ttccaaaatt
      661 tcacctcata aaatttattt aaaacgcatc aaatacaact aaagtaataa ataaaattaa
      721 ctcttattaa tgtgatatat ataaacaata aatttagaca tttattattt atatatatca
      781 aaaaattcta tctcaaactt ttcaatatta tcattgtaat ttgaattatc atatacttct
      841 tcaacaacct ctttaattgg gaatataact tttacattag ttccttctcc taccttacta
      901 tctatgtaaa tcttcccatt ttgaatttca atcaatgatt ttgtaaggca taaacctata
      961 ccacttccaa attcatttga tataccactg ttttcaattt gtttaaatcg attaaatata
     1021 tcctttaatt tttctttgtc tatgcccact ccagtatctt ttataattat ctctactgtt
     1081 tcgtcttttt tatatatacc tacaaggatt tctcctcctt ctaaagtaaa ttttatagca
     1141 tttgataata tatttagtat tattctttct atcgattctg ggtcaagccc taccataaca
     1201 gtttcttcat ctgtatcaaa aattaaatct attcctttag acttagcata actactaata
     1261 gatgtaacta ttctttctgt tatgtcaata atatcaaaat taactgcttt aatcttatat
     1321 atgtctgact taacttgaga aatatttatt atattatcta ttaatctcaa taatctaaac
     1381 atattttgtt tagttatttt tatatgttct tttagtatat cctgaaaatc aattattttt
     1441 ccttttttat aaaggttttc aataagttga actgaactat atatattatt taaaggtgtc
     1501 ttaagttcat gagatatatt agcataaaac tccatcttca tttggtcata ctgtctttgt
     1561 tttattaatg cttttttaag tctttcagac tctctttgca cacttaaatc tttaataatt
     1621 ctcactctac ttcttttctg tccaaagtat aatgttcttg atatcatttt tacttcttta
     1681 atgtgattat tttcatttac tatatggata ctcttctctc tttctcctat atttaaattg
     1741 tttatgtatt tttttactaa tatatttcta tatttttgtg ttgtaactcc taatacatca
     1801 ctagaaattc cgaacaactc tctaaaggct ctatttgtat atagtactct tgatgtactt
     1861 aaatcctcaa gaaaaatagc ctctggtata acatccagta atttttcata tattattttt
     1921 tgttcattta ctgttctaag aatatttatc tctttagtta tatctctaaa tgtaagcaat
     1981 ttaaagagtt tattatctga ccaatagtct ccaactctaa cttcttcaac atgttcttca
     2041 ccttctgagt cagacatcac aaaattaact atacagtttg ctgtgtcatt gtaacttact
     2101 atttcagctt tcttttcttg tgttagattt aatcttttaa attccctatt gtcaaagaaa
     2161 tctatgttaa aagtttcaaa atattgttct aatgtcatat cgactaaatc acttgaaaca
     2221 catttaaaac tcttttcata ttttttattt atacttatta ccttattctt ctttatgcca
     2281 ccttcagcac ttcttacaag tataggagat ggaatattta gtataatgtt ttcatagtct
     2341 ttatttatat ttcttatttc ttcatctatt ttgatttcat ttgtaatatc atttaaactt
     2401 attaagtaat tgctttcgtc tttattatta cttaaactta acaaataaat tttatcattt
     2461 aactctacca gtttatcaat tatacttata tcgttatcaa atttcttcaa tttttcagca
     2521 actttttcat cttcctttat aaaagttaat attttataat aattattcat atcctttgaa
     2581 aattcatctt taaatttatt atttgtgtaa cttatattaa aatcatagtc tgttactatc
     2641 catacatttg gtattgtatc cagagcttgt ctaagtaatt cttttctctg gtctatgtag
     2701 ttttttaatg ttctttgtat aatcatatcc ttttctattg ctaaatttat ctttcctaat
     2761 tgctctgact ttttacttaa ttttttattg attgaatcaa gttcataata tggatacact
     2821 actctattat taagactgta tacatataca taataagtat ggttacataa tagtaaatat
     2881 attactccta ttaatctatc tgaatctact atattaatct tagaaattgc tacaaaacat
     2941 ataatagttg taaaaaaaac aaaatatgtt aaatctttta ttaacttata gtgctcaatg
     3001 ttactatcaa gtttattcaa caaatatagt aaattaaaca tagatataca aatattaatt
     3061 aatataataa tcatattcca gttaatatca ctaaaaatat ttcttataaa gtaatctaat
     3121 atcacaaaag cactataaaa aattagtatt gggcttattc ttagtttttt tactttagaa
     3181 atggttaagt atataaaagt agacatatta attatgctta agttaagcaa tacaatttgg
     3241 aatttttgaa tttttaaatt tactactcct aaaatactta caaaaactaa tacaagacac
     3301 cctactttca atatatttat aaattcatct gttttaaagc tacttatata aactatagaa
     3361 tatccaaata tccaaagtaa aattattcta tacatattta tagaaactgt atacaaattt
     3421 atatttaaaa gtgcaataac caaaaataac ccattagcta gtatatagac cttattctta
     3481 cttaaagttc ctttagattc catattcccc accacttctt catttttata tagttttacc
     3541 tataaatatg ttaccacaat tcttccaaaa aatttgtcac tttctagtta taaaaaaaaa
     3601 tgagtaaata tttttaattt tactcatttt gtagattttg tatattcagt ttaaaaagct
     3661 ggaactatac ttcctttata ttcatcttgt ataaattttt taacttcttt actattcata
     3721 gcctctgata aagccttaat cttatcacta tctttattat tttctctaca agctattata
     3781 tttacatatg gagaatcact tgattctatt actattgcat ccttagtagg atttaagtta
     3841 gctgttaaag cataattaga atttattact gctccgtcaa catcttttaa tactgttggt
     3901 aattgctctg cattcatttc ttttattact atatttttag gatttttagt tatatctttt
     3961 ttagttataa gctctccatc ttttacttct atcaatttat tttttgctaa taatttaagt
     4021 gctctagctc cattagttgc atcatttggc acagctataa cagctccatc ttttaattca
     4081 tctaatgact taactttttc tgaatagaat cccattggct ctatatgaac tttagatgta
     4141 taagtaagtt tatatccttt ctccttcaca gtttcctcta aaaatggaat atgttgaaag
     4201 aagttagcat ccaaagaccc ttcatctaaa gctgtatttg gaagtacata atcatcaaat
     4261 atttttactt ctaaatcata tcctttttct tttaacaaag gttttgcaac ttccaatatc
     4321 tttgcatgtg gatttgatga agctcctact agtatttttt tatcctcttt gtttgaacaa
     4381 cctactgctg atattgctat tgctgacacc aatgctactg ataataattt ctttaatttc
     4441 atttttactc cccctcttta aaatgtttat aattaattta ttttagtttc ttataagcca
     4501 gatttcctac tccctggatt atctgaacta atattataag tgctattaca gtatatacca
     4561 ttactgctgt atcaaatctt tgatatccat aaataagtgc tatattacct aatcctccag
     4621 ctcctactgc acctgccata gctgtataac caagtataga tattattgat aatgtaattc
     4681 cagatactat tgaaggcata gcttccttta tcataacttt aaatactatt tgtctttttg
     4741 tagctccaaa agattttgct gcttctatca atcctttatc aacttcattt aatgagcttt
     4801 ctataattct agcgataaac ggtgctgccc caatagttat tggcactatt gcagcagttt
     4861 cccctatact tgttccaacg attaatctag ttattggaat cattgcaact ataagtatca
     4921 taaatgggaa acttctaaat atatttacta taaatcctaa tgcactattt attgtgctat
     4981 ttggttttaa tccatctggt tttgtaacta ctaatatgat tgctaatata aatcctaata
     5041 ttgttgccac tatagttggt actataacca tatacaaagt ttgtaacaat gcatttggaa
     5101 atagtgttgt taaaaagtca attaaactat tcatttatca tttcctccca tcttatgccc
     5161 ttactagtta gatattgttt tacttgctct ccacttttat ctgaaatgtt tataataagt
     5221 gaacctaaaa tatcatcttt aaattgttct aatttcccaa atattataga cacatctata
     5281 tttagttctc ttgccatagt cgtaataata gcttcattag aaatatcttt agggaatagt
     5341 atctttatat ttgttccttt tggcaatatt atactttctt cacctattaa ttttctaagt
     5401 cctttagtat ttcttaagaa tatttcttct gtatctccta cctctaatac ttctccattt
     5461 tccattattg ctactcttcc acaaatctgc tttataactt ccatttgatg agttacaact
     5521 attattgtta ttcccaattt tttatttata tcttcaagca atgaaagaat tgactttgta
     5581 gtatttgggt ctaatgctga agtcgcttca tcacaaagaa gtacttgtgg atttagtgct
     5641 aaagctctag caattgcaac cctttgtttt tgtccgccac ttagatttct gggtttatca
     5701 tttttctttt cagatattcc aactacttct aataactcta aaactctttt tttaatttct
     5761 gcctttgagt atccaaaaca ttctaatggc aatgctacat tatcaaatac agtttttctt
     5821 tcaagcaatg aaaagtgttg aaaaatcatt cctaactctt ttcttaaatc tctcatttgc
     5881 ttttcattca atgactttac ttctttatca gaaacaagta cactgccttc ttggtattct
     5941 tctaatccgt ttatacatct cagtagtgtt gatttccctg caccactatg acctattatt
     6001 ccaaaaattt ctccagattc tatttcaata cttacatctt taagcacttg aatctttcca
     6061 taatacttat taacattttt tatgctaatc ataaaatttc ctcccatata ttctgctcag
     6121 tttttatgtt tatcctctct tatgtattac aacaaaataa aagcccgagt ataaactcag
     6181 gcttagaaag ctatttatac tcatctatca actatattag ttgcaggatt tagcaccaat
     6241 gtatataaaa tatactggtt gccgggtttc aaagggccag tccctccacc actcttgata
     6301 agacgttatt taatttaatt ctattatcat ttgttgctat gttatatatg atatattcat
     6361 taatagtatt tgtcaataaa tttatttaaa ttttttattt tttattatcg ttaattaact
     6421 atttttaatt agttttctag ctcctaacac tttatatttt aatgtctata taactataga
     6481 acatcattat aagaaataaa ttaaataaca tcaatctatc taaatcatct gtaaagtaaa
     6541 ttaagaaaat taacatttta tccaaactct atcctactat taaataaaat aatttaaata
     6601 caatgatgat tatatagctc tagtacttta gactttatca aatgtttaag ttctataggt
     6661 tctattattg tagcattttt cccaaaagtt aaaaaatatt cagccaccca gttaagtgta
     6721 gattttggta tatacatatc tatgtatcca cctttagaca agattttcaa ccctcttgcc
     6781 aacaaaaatt ctgtttcaca acgttttact ccctcatctg tcaaattaat tttaatatga
     6841 taatctgtac ctacttccat attcttaaga taatcatgta tagaagataa aaccttatat
     6901 ttcttacttg ataagttttc tatactcaaa atcttcacaa ttctgtctac acgaaattcc
     6961 ttaatagatt ctgattttat acagtaagct ggacaatacc aaagtccatt catggcatac
     7021 aaaccaatag gaacaatggt acgtacacta tttttttgct ttgatgaata ttcaatttta
     7081 attgtaaatt cattcattac tatattaaac aattctttca ataatggtgt tgaacagtgc
     7141 ctatctggtg tccaaaaaac aaatttacgc cttatattct caatattata ttgaatatca
     7201 tttggtatac aatttaaaaa tttttttaaa acagaaatag tttcttgctc aaatggcaaa
     7261 tcattataat attctagtga ctgatatgca aagaatatag attttacctc actttctgaa
     7321 aatgcaatcg gtggaagtat acgctcttta agtacatgat atccaccagc cgctccaact
     7381 tttgaatata atggaaatcc aatactctcc agcacctgta aatctcttag tatagtacgt
     7441 tttgatacag aaaattcttc tgctaattct cctgctgtaa aacttctttt tgcatttatt
     7501 gttatcatca gttcaattaa acgctcagct cttgacatat ttatactcct aatttaaata
     7561 tagtgacaat aattgtcact attatatgat aagatattct tgcatctaaa gcaataataa
     7621 tagtaaagaa agaagggatt gatactttat ggaaaatgat actattaagg ctgatgatat
     7681 tctcaattat tgtctatcaa acttagatga tgttgtacta atggatagtt ggggggaacg
     7741 agcaatttac tacaatccta atggtgtttt aaagcgaggg gtatatgttc ttaccattaa
     7801 ggaaaaagac agtaataatg ataaaggttc gttagttagt cgtccaaatg tataccgtgt
     7861 gaatatagga ttaaaaaaag aaacttttat tgaaatgttt ggatatattc caaagcgtcc
     7921 aggtgtaggt caaatagttg atatggattt tgattttaca aaattggaca caatcatgcc
     7981 acatcctatc tactcatgga tgggatggat atgtgtccta agccctactg aaaagacatt
     8041 tgagaacttt aaaactttaa taggagaatc ttacaatttt gcaaaacaaa aatttaaaaa
     8101 gagaaaaaac aagtaaaaac gtgtgaaaat aacctctaaa taaattataa taaaaatatt
     8161 aaggttacaa gataaaaatt aatatcttaa taacatgcaa aaaagcgaag ccaaaaaatg
     8221 tattatttat aaggcttcgc tatatctcaa ataatttatt tcaaatttca aaactattta
     8281 ttctattatt tcttattatt tcctgttatt cctaatctat cattcatatc ttttatcatt
     8341 tttctaaaac cactacctat atcatttcca acatcttcag ttccatgaac taattttata
     8401 aagtcatttt gacctttttt catatcttca tcagatacct tatctaattt ttctattctc
     8461 ttatctatat cttttactaa tctttcccct tcagcgatta ggtcatcatt cattttcttt
     8521 aactctgtat cttctgtttt accatctttt ttaagagatg ttacaaatga ttgtatttta
     8581 tctctactat ctttatatgc agcctttaca tcacttagat atttttcatt tcctggatat
     8641 tctttatctt taaactgatt atttatactt tctggagtat cataaataga atatctattt
     8701 agacctgcta tataatcatt atagcttgtt gaataataat tcatatatcc ttcattatta
     8761 tttacagatt cattaggatt ttttcctgta ttttcacttg gtttttcatt atttttagta
     8821 catgcagtta tacctatagc taatactagt gctaatccta caaataaagt tctttttaat
     8881 ttcattttta ttaccctcct agatgtttta tactataaaa aattttaata attttctttc
     8941 ttaatttagt atttctatat ttttatattt tatttactaa aattaaacaa gttataattt
     9001 atttttttgg aaatcataat gaataaataa ttaaataaaa aaattataat tttatcattg
     9061 atattgatta tcattcatag tataatctaa ttacttgata ttaattttca tttgaaggag
     9121 gttatctttt atgtcttgtt gtaattcaca attttgttgt aaaaataaaa ttgaatcatc
     9181 atatataaaa tggcttttag aagttttagg tccagtcttt ttaggctcta aacctgctga
     9241 aataataaat atttcgttta ctgatgtaaa tagagaggaa aaaattaatg atatttataa
     9301 atatctatat aagtgtaaga aaatagattt tatagttatt gataaagaaa aaaagggatt
     9361 aaaaatctta tttgtaaata aaaaagcatt atcagaaaaa ttaaaatgta aaaaaacagt
     9421 aaacttttta aagtttttag gatacaaaca aaatacgaat gttaatgctt atttagagca
     9481 tttagtagat aaacttaaga gtgatgtttt tcctgatgaa ataggtattt ttttaggata
     9541 tcctcttaaa gatgtgattg gatttatggg atatagtaat tatgaagttt ctatgattaa
     9601 atattggaaa gtttatggtg acacaaaaca atccgaggac acatattcga agtttttact
     9661 tcaccgtaag aaaatgagaa aattactaga ctacataagt gtagataaaa tagtaagctg
     9721 tttttaattg tgtttttgta taataataaa aatacaccct cttttaccat acagtttcca
     9781 taataaataa gggtgtattt tccactttaa tattttaaag tattctaatt ttgattgtac
     9841 aacatatctt taatatttat tttcttttgt tgcattccat tagacatcaa aaattcctgt
     9901 gtatcttcta attcttttat atccttgtcc gttattttag aactaaagtc ataccaagaa
     9961 tacatttctt ttgtttcatc taaagataaa ccaacttctt tagatacaac atccatcact
    10021 tcatccttgt tttcattcat atattttaaa gtttcttcat gaaccttcat aaatcttttt
    10081 actaattcag gatatttttc agcaaagtca tcacttacag cagtaactat tattccactt
    10141 actaatcctt ctccatttac aatcattttg gcacctgaat ttatcgtttt caatgccact
    10201 ggacctgcaa gcattgctac atcagcactt ttactttcta atgcagaagc agcactagga
    10261 atatccatat ttacatattc aacatcatct atagtatagc cttctttagc aagtgcagca
    10321 atcaacagtt gatgaagtat agtccctttt ggacctacaa tttttttacc ttttaagtct
    10381 tttatagatt taatattatc attattagtt ataagcatat atccttttgg tgaacggcta
    10441 taaatattcg taattttaag accaacacca tttgatgcag ctattattgc agacgttcct
    10501 cctaatgcat gtaaaaagtc tagctcacct gctgctaatg cttgagtttg ctctggtcct
    10561 gttgtcaatt catggaaatt gacttttata ttgtcctttt taaattcctt tccaaataaa
    10621 tcatcctttt tttctaatat actaggaaca ttaagtggtg attttacata agttaaattt
    10681 atttccttag gtaaactagc ctcttttttt gcaggttcat ctttcttatc atttgttgtt
    10741 gaacatccta cagtcccaac caacaccatt attaaagatg tcattactgc taaaatcttt
    10801 ttgtttcttt taatcaatta aaactccccc aattccctta atatttcttt tttcaagttt
    10861 atataatagt ttttagttaa atctctatta tattcatctt cgacactaaa ttgtttaatc
    10921 cttttatttt tactaaaaac aattattttc tttgctattt ccatagcttc ttcaatattg
    10981 tgagttacaa atactacacc ttttttagta tttttatgga tatttacaac ttctttttgc
    11041 atttttcttc ttgtgaagta atctagtgct gcaaatggtt cgtccatcag caaaatatcg
    11101 ggattgaagg aaagtgctct tgctatactt actctgtgag ccattcctcc tgataattca
    11161 tttggatatg agtttttaaa cttttcaagc ttcatcattt ttaaatactt gtctaaatca
    11221 actttatttc tattatcttt ttcagtatgt aaaagtatat tttcacttac attcagccat
    11281 ggcataagtc tactttcttg aaataccatt cctacttttg gagtacactt tttatcatta
    11341 ttaaaaaaat atacgtttcc actagtagca ttttcaagcc ctgctaaaat tctaagtagc
    11401 gttgttttcc cacatccact ttcacctaat ataacagtta tctcttcact agatatattt
    11461 aaagatatat tatcaagaac taaatgctct ttattatcaa ctaaatattt cttatatata
    11521 ttctctagca aaaatccact tctaaccatt taaatcaacc tgcttccctt tgctaaattt
    11581 tgttattatc tttgaaaata gataatctga aagtatacct aaaaatccaa taacaaaaat
    11641 tcctaccaat acaacatcag ttctagacat atcttttcca tcagaaatca aatatcctag
    11701 tcctgaagaa gctgcaataa gctctgctcc aattatagcc ctaaaactat acccaagccc
    11761 taaactaagt ccaacaacaa tatccagcat agaattaggg attattattt tataaaaaat
    11821 tctcttttta gataaattaa aagatttacc tacttctatt aatttattgt cacaattttt
    11881 tatacctttc aatgtattta aaaatattgg aaaaaaggat gccaaaataa taattataat
    11941 tttagattct tcacctatac caaaccataa aataagcatt ggcaccaaag ctagtggagg
    12001 tgtacttcgc ataaattcaa atagtggttt gaaatattca tacatttttt tatttgctcc
    12061 aaataaaact ccaagtggta tagccatcaa tgaacttatt aaaaaaccta ttaatatcct
    12121 tcttacactg gcataaacat ttaagaaaat agaaccgtca tatatcattt ttataaaagt
    12181 atctaagact atttcaggag gaggcagaat atagctactc catataccca aaacacatac
    12241 tatcttccat aaaattaaaa ttattaaaaa aatataatat cctttaagcc ttttatgaat
    12301 tttctcaaac atataaaact ccttttaaca tatctatccc tgctaccctt tttatttttt
    12361 aatatcttaa ataataatta agctatatca taagatttaa tctatgccaa gtcttaatcc
    12421 acctgaactc attctatcag aaggtgtaga atctgttttt aagccagaca atctttcaga
    12481 tggttgtata atgactattt gtccaggttc aacaaattcc atatgataag attctcctga
    12541 agtctgacca ataaaagtct tccatgatag ttttgatact ttaggatatg gttctcttcc
    12601 agtccaagct actaatgcat ctgggtcaac acaacaaggt ccttcaagaa ttagaggatt
    12661 accatctgtt attatagcaa catcttgatt ttgacctgtt ttatttacta aatgtgtagt
    12721 aaaaagacct ttttgagata ttacccctga accaatcaat tttacactgt aatttaattg
    12781 ttcagaaaat gccaataagt tttcactctc aacataaatg gaatcacctg ggtcaattga
    12841 tattacatct acatggtaag cattttgagc taggtaaatt tcaccttcac cttcaaccac
    12901 cattattggc atttgttctc ctgtcaatga cctctgaaca tgacctaata atgctcttcc
    12961 caatccaccg ccattacttg gacctaacag caatttttca aaattaaaat ttcctttaaa
    13021 ggctaccata gcaccttttt ttgcaaaaaa tttaccactt ccccttgcta tacacataag
    13081 ctcgtttgta acatcaaatt taaacataat attcacttat attgcttaat ttagcaataa
    13141 tccctcctaa tcatatattt atatataatt atacagtaaa attacagcat agtctaacct
    13201 acttcaaata tgaaatttgt tatttataca aaaaataaga acctgataat aaagcaattt
    13261 aactttttat caggctctta tcctatttat ctcttagcgc tatgacaact cttactactt
    13321 gagcatccag aacaaccaca tccacaactg ctaccattct tttttgaatt tttaaccata
    13381 tacattacag ctagtgccat taatactact acaatagctg ctataataaa tgtagccata
    13441 ttcatcactc cttatttata tgaattaatt tttcatataa cttaatttac ccattttttc
    13501 ttttttcata tttttatttg aataagttaa aactacaaag actactgcta ctgctataaa
    13561 tatagatatt attgccccag caatacttcc tccagtacct aaaactaaac ttccaacttg
    13621 atttataaga agagcaatta tatacgctgt taaagtttgg aatcctaatg taatccatgt
    13681 ccatttccat gaacccattt ctctttttat ggctccaata gctgcaaaac aaggtgcaca
    13741 aagcatatta aatgccataa atgcaaacgc actagctact gtaaacatac ttgcaactga
    13801 agcaagaagt gttgggtctt gctctgttgc atctgatata ccaaataaaa ctccaaatgt
    13861 tccaactaca ttttccttag ctactagacc tgtaactgtt gctactgatg attgccaatt
    13921 tccaaatcca agaggagcaa atattggtgc aactatattt cctaagctag ctaatatact
    13981 atctccagca tctaccattt gtaatgacca attaaatgat tgtaagaacc agattactcc
    14041 acaagcaaca aatataattg ttcctgcttt gattataaat gcttttcctc tatcccacat
    14101 atgtattaaa acaccttttg cacttggaat atgatattga ggtaattcca taacaaatgg
    14161 agatggttct cctgcaaata aactagtttt ctttaatata attccacaaa tgattatcat
    14221 tgcaatacct aagaaataca ttgatggagc tacccatgaa gcacctccaa ataatgcccc
    14281 tgcaaataat gctattattg gaatcttagc tccacatgga atgaatgtag ttaacataat
    14341 agtcattttt ctatctctat cattctctat agtacgagtt gacataactc ctggaactcc
    14401 acaacctgaa cttataagca ttggtataaa tgattttcct gaaagaccaa acttacggaa
    14461 aattctatcc attataaaag ctacacgtga catgtaccca caatcttcta atattgataa
    14521 taataagaat aaaagcatga tttgtggtac aaatcctagt actgctccaa ctccaccaat
    14581 tagaccatca actacaagtc cttgtaacca ctctgctaca tttaaagaag ctagaaaatt
    14641 acttacattg ccttgaataa tttctccaaa cagtacatca tttgtccaat cagttgctat
    14701 agtacccaat gaacttactg ctatatagta aactccccac attataagtg caaaaatagg
    14761 taatgctagt atacgatttg ttacaatctt atctatctta tctgatacag tttccttacc
    14821 ttttcgattc ttctttatta tacttgaaat tattgaacta ataaattcat aacgattggc
    14881 tgttattata ctttcactat catcatccaa ttcatcttca caatttctag ttatttcttc
    14941 aatactattc aatattgttt tagaaatatc aagtttttgt ataacatttt catctctctc
    15001 aaatagcttt atagctaacc agcgtgtttc tacatctata tatggagtct tttcttctat
    15061 tattttttca attttttcta ttgcatcctt actttcatca acaaagggta atttgaaatt
    15121 taatttattg ttactacttg caagttcaac tgccttttca gcagcctcca taattccttg
    15181 acctttaact gctgttactt ctaccactgg gcaacctata acttcagata gttctttaat
    15241 atttatctta tcaccattct tatttacaat atccatcata ttaagagcta taacggtcgg
    15301 tatacctagc tctaaaactt gagttgtaag atataaattt ctctctatat ttgatgcatc
    15361 tacaatattt attactgcat ccggcttatc atctagcata aaattacgtg taactacttc
    15421 ttctaatgta tatggagata aagaataaat acctggtaaa tctactattt ccacatcttt
    15481 atttcctttt aattttccac cttttttttc gactgttact cctggccagt taccaacata
    15541 ttgtgatgag cctgtaagcc cattgaacat tgttgtctta ccacagttag gatttcctat
    15601 gagacctatt tttattgaca tttccattcc ctccattatt atttaaatac atcactgttt
    15661 gtgatacaga aaatcattct cattatataa ttacattaac cctactctaa ttaatcttta
    15721 ttattccaca ataatttttt ctgcatctga cttacgaatt gatagttcat aatctctgac
    15781 tgttacctca attgggtcac caagaggagc tacttttctt ataaatatat taacacctct
    15841 tgtaatcccc atatccatta tacgtcttcg tgtagctcct tctccctcta actttttgac
    15901 ttttacagtc tctccacact taatatcctt cagtctgttc atgtcattac ctccctatat
    15961 tattattcta cttgccattt ttttatctaa tgcaactcta gtatctttta cgtctattat
    16021 taagttacca tctatcttag aaactatttt aacatttgta cccactacaa aacctatact
    16081 atttaaaaaa gtcctcgtct tatcacttcc cgaaattttc tttataacta cttcttcacc
    16141 tgtatttgat aatatcaatg gcatcatata atatccctcc tcttaaagta atttaaatct
    16201 acaagcaatc gttatcttat atataaatta caatacctta aatcttaatc tattaaaata
    16261 acatcctatt ttttccttct ttttacaatt cctaattttg atttaagtct atcacaatag
    16321 tatatttttt gcaagtgatt attgtattct tttgattttt tttctcattt gatttatttt
    16381 attaataaaa tcgtaaaaat taatacaaaa ataaagatgc tctaaaatag tatactcaac
    16441 taatattaaa gcacctttat tatatatgtc attatttaca cattgcttta ttctttttta
    16501 aaagcgattt tttcaaactc ttttacaggc attggcttag aaaacaaata tccttgtacc
    16561 atatcacacc caatttgctt tagaaattct acttgcgaaa tagtctctac accttctgat
    16621 attactttca ttttcagttc ctttgccatt ttaatgacat tagatataac aattttttca
    16681 ttattactct catctttttc tgtaaaaaat gctctatcta gttttaatat gtcaacaggc
    16741 aattctttta aaagattaag agaggaatat cctgtaccaa aatcgtccat agagattaca
    16801 aatccctttt ctttcaaatt gttcattgta tcaagtaatc cttctatatt atctaatact
    16861 gctgtttctg ttagctctaa ttctataagt cttgtcggaa ttttgtattt atctacaatt
    16921 aatttaaact cctctataaa attactattt acaaaatgca ttcgagacaa gtttacagat
    16981 ataggtacta ctttttgtcc ttcatccatc cattctctaa tctttttaca cacttcctca
    17041 aatacataga aatcaatatt tacaataaaa ccattcctct caaatacagg aataaattct
    17101 attggtggta ttagaccttt ttgtggatta tcccaacgaa caagagcctc tgcccctata
    17161 atttgataat ctgaaaggct atatttaggt tgaaaataaa caataaattc tccattatta
    17221 agagcatcta ccattgaatt ttcaatttct ttctctttta atattttttt gtgcatttcc
    17281 ttatcgtaaa aagcaaatga atttttatga ccacctttta tagtttttct tgcagtatta
    17341 gctctatcca taatagtatt tatgtcatta tcacttttac ttattttata tataccacaa
    17401 tctaaaatca atttataata gtttatttta ggattactaa gtatttgaac cttattgtaa
    17461 atattgttta accttgtttt aatatcatca tctgtcttat acttaataag aagaacaaaa
    17521 tggtcagcag aaactcttgc aaaaatttca tcttccttta attcacttgc aatagtattt
    17581 gatatatgta tcaaagtatc atttcccata tcatatccaa acatatcatt tatatattta
    17641 aatttgtcaa catctatata aaacaacgca tattcttctg gattattctt agcaaacagt
    17701 ttattagaat ttattttaaa tttatctata ctatctgctc ctgtcaatgg gtctgtatat
    17761 gctatcttcc ttagataatc ctctttcttc tttttattat aaattatata tttaatagca
    17821 attaagaata aaatacatac aaaagaaata atttgtattg aatattcttt aaaaatcaca
    17881 ccaaatggta ctttataagg tttgtcaata gtattagaat atatacaatc acttaattct
    17941 tcttcagtaa ttttgtctat tgatttattt aaaatagaca ctaatatagg gtcagtttta
    18001 tttgataccc ctatacgcat cccatagctt gtatctaaaa cagatataac agataaattc
    18061 tcactctttc cttctcttaa aagttcatca aactgataag aactaagtat cattaagttt
    18121 gctttacctt catttatagc gtttagacaa ctttctacac tcttataaga tgttgtctta
    18181 gcattttcaa aactcttttc tatataagaa tcaatagact tataactact agttaaagca
    18241 atatttaaat cattattgag attggtatcc aattttccta ccataatcat tggaatattt
    18301 atgtatggat ttgtcaattt catattaaat cgttttacct tatcattttc attgattgag
    18361 ccacatagca tagttgcctt accacttttt atgtaatcaa gactctcatt ataatttttt
    18421 gttttaatat attcaaattt tataccacat ttttttgata taattgacat taaatcggaa
    18481 cttatacctt taaatgaatt gctttcttca tcataatact ctacaggaga ccactctgaa
    18541 tcatatacca tagtaagttt tgggtttgct ttaataaaat tcatttcttg ccgagtaaat
    18601 gctatggaat tattgacctc tcttttgaaa tattttttat ataattccaa ctcataatac
    18661 atatcattta tttttaattc ttttaaagca taatctaatt cttttactaa attaggttta
    18721 tcttttgcag tagcaaaata aaaaggttct actgaaaatt tgctaactat tttcattcct
    18781 ttagcattta taatacttcc acaaacaaat gcatctgcct ttttttcatt gacggactca
    18841 attaattcat caatagaatt acagtatata tattcaactg aaaaattatt ttcttctcta
    18901 tacttctcaa atgcagtatt atgaaagttt cctctaagta cagctactct cattccctta
    18961 aaggaactta tatcttcata aaacatatta ttgttactat cctttgtata tagtgcacta
    19021 tattcatatc ctgaacttag tttaggaaaa ttaaatagtt tatttctttc atcattcttc
    19081 tgtaaaggtc cgagtaagtc tatttcaccc ttttctagtc tgtctaaaca ttcttcccaa
    19141 gaccctttta caaattcata ttcccatctt gtatattttg agatttctct tagataatca
    19201 taaccatatc ctgtataaga atgctctttt gatgaggata ttattccgta gtcatcacaa
    19261 tatccaactc ttattttttt tgaattttca gactcatcag caaagcatag tatattgtta
    19321 aaacatgata taataagtaa aaatatcaaa gaaagtatca agaagtgctt tttaaatgct
    19381 ttcatattta aaaacctcca atttgccaac ttactttaac ttatttcgtt ttctagttgt
    19441 aactactttt attgtaatgg taaatatatc aaattgcaat attctcatat aatattctta
    19501 ttcaactata atgaatttat tattatctat ttaaatacac tatctaatat tagtttctta
    19561 taagtcataa aagcacaact aacactataa ttctagtgat taattttatt tcaaaaaata
    19621 taataacact actaatattt taaatatcaa tagtgtcata aaaacttttc agattaatta
    19681 aatctttcta tatattttat aataatctaa atcatgctaa atatttagac agaaaacttt
    19741 tttctttaat agtaaatact tttgtttgaa tatcagaata attatttgaa tatctatcta
    19801 taaaaccatg atttgcatct aaaatctcaa tttggatatt ttgtttccta gaaagttggt
    19861 aagaaataga atcaacatca aatgaatcgt gctttgcaaa tactaataag gtaggacatt
    19921 ttggaattac atccatgtaa tctctaatcc gagagccata acaacaaatt atgccatcac
    19981 aaaaagaatc ttcactgcat ctccatgcaa tagttgctcc cacgctatac ccagcaacaa
    20041 atacatattt atactctgat tttaaatcat ttataagctt ttcaactttt ttataaatat
    20101 caaaaccaac attatttata aaaaaatcat atgcctcttg gacttttgaa tatggaaaaa
    20161 ctcttttttc tcccagaagt tcaggacaaa atacatcata tccatattta taatactttt
    20221 gacaaacatc ttctataaag ctattaatcc catagatttc atgcaaaaca acaatagcta
    20281 catcactttt atgtatatac tttatcagat tatccaccac ctttacaaaa cagcaaattt
    20341 tttatactta gtttaatata ttcttcttta catgtcaatt tacttttcta aaatcaaatt
    20401 tatttttgga ttaatcattt atttttaaaa gttgtgcatt attactatta aattattctc
    20461 tattattaaa aatataatcg ttagaaataa aaaataaagt acaaataatt aaaaaatatc
    20521 tcactcataa ctttaaaaat tataagtgag atactcctaa aatctacttt atattaaatt
    20581 tattttccaa aatatctatt taataatcct aaaaatgctt taccatgtct agcttcatct
    20641 ttacacattt catgtactgt atcatgtata gcatctaatc ctaattcttt tgctttctta
    20701 gctaatttta attttccatc agttgcacca tactcagcat caactctaac tcttaagttt
    20761 tcttttgtat ctgcaactac aacttctcca agaagttctg caaatttagc agcatgttca
    20821 gcttcttcaa gagctattct cttataagct tctcctactt ctggataacc ttctctatca
    20881 gcttgtctac tcattgctaa atacattcct acttctgtac actcaccaac aaagttagct
    20941 cttaatcctt cgattatttc ttcatctaca ccttgagcta ctcctattct gtgctcatca
    21001 gcccaatttt tttcgccttt catttcttca aatttatcag ctccaacttt acatactgga
    21061 cattgtgctg gtgcagcatc tccttcatgt atatatccac atactgtaca aacaaatttc
    21121 ttcataatta ctttcctcct aaattttata tatcaaatta aattttttat ttattaagtt
    21181 agtctatata tacccgcacc atataccttt aaacaatttt tttaaaagtt ttttctaaat
    21241 acttattttc cctgtgtcaa taatatgttt ctataataat gtccctttaa ttttatcaat
    21301 tctttatgat ttcctgattc cacaattcta ccattttcta aaactattat attatcacaa
    21361 tttgatatgg tacttaatct atgagctata attatacttg tctttccata agttaaatta
    21421 tttattgctt cttgaatttt agcttctgtt gctatatcta tgttacttgt agcctcatcc
    21481 aaaataagta ttggagcatt ttttaatact gctctagcaa tacttattaa ttgtttttga
    21541 ccttcactta aatcttcacc cctatccgat aatacagtac tatatccttc acgcatttta
    21601 actataaatt tatgtgcatt tgctatttta ctagcatata taacttcttc atcagtagcc
    21661 tccagatttc cataccttat attttccata actgtatcat tgaatatata accttcttgt
    21721 ggaactactc caaaacaagt tctcaaatag tttctgttaa tagagtatat atccttacca
    21781 tctaaaagta tacttccttc atctatatga taaaaatttg taattagatt tataatagtt
    21841 gtttttccac ttcccgtctc tcctatgatg gcatttgatg tgccagcttt gatttttagg
    21901 tttatattat ctaaaatttt cttttttgaa tcataagaaa aacttacatc tttaagctca
    21961 atttctccct ttacaaaatg agagtttaaa ttaccatctt tattatcgtt aatctcactt
    22021 ttaaacatgt tatgcacttc ttgctcttct tgttcatcta taatttcaaa aactctttca
    22081 catccagcta tggctgaaag taatgtatta aatagatttg ctaattcatt taaaggtctt
    22141 gtaaattgtc ttacataact taaaaaacta gctataaccc ctatggttat aatatcttta
    22201 gatgcaagaa tgcctcctat aatacatata gttgcaaatc ctatattact aatcacattc
    22261 ataataggca ttaaaagaga agtgtaaatt tgcgatttaa gggaaatatt tagaattcta
    22321 tcattgactt ctttaaaatc atttacagat tttctttcat aattaaaaga ttttactaca
    22381 tttatgtttg atatcatttc ttcaatatgt gcatttagtt ttcccaactc aacttgttgt
    22441 tgcttaaaaa aaactctagt tctctttgca ataaaattac tcacaaacat tactatcggt
    22501 attaatatta cactgcaaaa ggttaaaatt gggcttaata caaacatcat aataaaagtc
    22561 atcaatatgt ttaagattcc tgtaattaac tgtactaatg aatttgatat tcctgtactg
    22621 atattatcaa catcatttgt cactctactc ataatatctc cagtagaact tttatcaaaa
    22681 aaggttattg gtagattttt aaattttaaa aataaattac ttctcatttc tttaactata
    22741 ctttgagata atctagctgt acatatcccc ttagacagtt taactgaaaa ctcaattata
    22801 taaaatgaaa gtaaaataat tattcctttt aagaaaatgg attttgaata agtatcgata
    22861 tctattatgt caactacctt tccaatagta tatggtatta cagttgatat aattgaatca
    22921 attattacta gcaaaaaaat aaatctagta atcttcttat cttttttaaa gtacataaaa
    22981 attcttttaa acgttttttt aaaatcttta ggcttttctt ttttctttaa tctactgacc
    23041 ttctgatttc cagtacttaa attcaatata cttcctcctt aatttacatc ttcacttact
    23101 aaattctgca acgcaaaaat ttttttataa attggagaac taaccagtaa atcttcatgt
    23161 gtagcaaatc caaccacctc accctcatcc aagactaaaa tcttatcaca gtcaattata
    23221 gaactaatct tttgtgaaat agttattaca gtacatttct tactttcctt ttctcttaaa
    23281 ttacttatat actcttttat attctttctt ataattgtct ctgtattaat atccattgca
    23341 ctaaaacaat catcaagaat taatatttgt ggttttttgg ctatagctct agctatagta
    23401 attctttgtc tctgtcctcc tgataaattt ttaccccttt ggaataaaac ttcatcataa
    23461 gtattttcga gttttgttat aaattgattt gcatttgcta tttcacatga ttttacaaca
    23521 tcctctttgc atatatctct atttcccata actacattct ccaatatact ttttccaaac
    23581 acactactat tttgaaatac tacacctatt cttgccctta aactttcttc agaaatactg
    23641 tatatactac gtcctccaat cttaatatca cctttatcaa ttatatataa tttttgaatt
    23701 aaatttacta aagaagtctt tcctgaacca gtttgaccaa tcacaccaat attttgacct
    23761 tcttctattt taaaggatac gttttttaat attttttcat ctgtattttt gttatacgaa
    23821 aaatctacat tttcaaaaat tatatcacag tttacaaact ttaaatcttt ttctccaaca
    23881 tctaaacttt cttctctctc aattacttct tcattctcat caaccaaaac ctcacttatt
    23941 ctctcataag atgcttttgc cctaacaaaa acattaaaaa catgtgaaat cattataaga
    24001 gatgttaata ttctagtcat atagtttaca taagcaacta taatcccaat tttaatttct
    24061 cctgaataaa ttaaatgcct tccaattagt aatattatta ttatggaaac attaatgatt
    24121 attgtaattg tcggtctaaa aaatgacatc atagttgtag cttttctact atttttaaaa
    24181 agttcatcat ttaactcttc aaagctttgg ttctcataat cgtatctaca aaatagttta
    24241 actactttta ttccacttaa aaactgtctt aattttgaat ttactttatc tgtactttct
    24301 tgtacatttt taaataatct ataccctatc ttcatattaa gcaatattat aataaatata
    24361 attaaaactg caattagaat aattattgac atctttaaat ttaattttat agctataatt
    24421 aaacttccta tacacattat tggtgacttt ataaaaactc tcatcattcc attaacgaat
    24481 tgttgcattt gattgatatc attagtaatt cttgttatta atgaagctct accaaattta
    24541 tctatttgtt ttaatgagta tgtatttatc ttttcaaata catcctgtct taaatcataa
    24601 gaaaaatgct gagaaactct tgccgagatt acacttctta ttattgcaaa tattgcacct
    24661 aaaaaagtta tacctatcat tatagctcct gttgatagta tgtagtctaa gttcttattt
    24721 gaaaccccta tatctattat ttttgccatt atagttggtt gagctaaatc acaaaaagct
    24781 tccaatgtta aaaaaaatac tgctgttaga aataatacta tatatttttt tatgtatttt
    24841 ttaaaatacc tcattcaatc atcccttcat agaattttct cattaccaaa agtatatcat
    24901 aatggctaat ttaattgatt atatcaatta taaatatttg atttattatt aatttttata
    24961 ccatatattt tataaattat ttgt
//
LOCUS       DAYAOO010000057        24978 bp    DNA     linear   BCT 12-OCT-2024
DEFINITION  TPA_asm: Clostridioides difficile isolate ST8-SSI-h139-18
            SAMN40601845-rid21577343.denovo.057, whole genome shotgun sequence.
ACCESSION   DAYAOO010000057 DAYAOO010000000
VERSION     DAYAOO010000057.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN40601845
            Sequence Read Archive: SRR28438827
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 24978)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 24978)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-MAY-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-MAY-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002157583.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002157583.1
            Genome Coverage       :: 163x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/11/2024 16:19:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 4,038
            CDSs (total)                      :: 3,963
            Genes (coding)                    :: 3,930
            CDSs (with protein)               :: 3,930
            Genes (RNA)                       :: 75
            rRNAs                             :: 6, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 60
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 33
            CDSs (without protein)            :: 33
            Pseudo Genes (ambiguous residues) :: 0 of 33
            Pseudo Genes (frameshifted)       :: 7 of 33
            Pseudo Genes (incomplete)         :: 25 of 33
            Pseudo Genes (internal stop)      :: 11 of 33
            Pseudo Genes (multiple problems)  :: 8 of 33
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..24978
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN40601845-rid21577343.denovo.057"
                     /isolate="ST8-SSI-h139-18"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Denmark"
                     /collection_date="2018"
                     /collected_by="Statens Serum Institute"
     gene            59..1915
                     /locus_tag="ACGI5H_002534"
     CDS             59..1915
                     /locus_tag="ACGI5H_002534"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902631.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HFG9698234.1"
                     /translation="MDTHNKYVNFIKNIPVPFLYCRIVKRQEDIEYRVEYISKGMGKV
                     LQLEEGICDKNILDVLPVFKSKKYFKELFSNEVDCIKRYIPTLKNWINIKKQIIGDSY
                     IILYFGKIVFDYRQIIDSFDKKEKVAYIKDEEGTYIDCSENLIPILNNNIKTTKDIFG
                     KNDIEVWGENTGKLFRDDYREGVSSKKRFLQNLFEYEETFFMVEKYFLYDEDELLGTI
                     GIVDNIIYSGYSNRNYNSKDLMKMIEHSIPENMFYKDVYGNYIGFNSGFLNLACMNKE
                     ELLGKNSYKISEEEALIDKIFESDKGVVENKKVVTFELNISMNDENKCIEITKRPFFD
                     SYGSVIGIIGTARDISRRKRLEEEMDKTRMEFFANLSHELRTPINLISSSLQVIEKKE
                     ADLIESNDTLKRNLGIIKQNGNRILRLVNNVIDFTKMQSGYLDFKPEESDIIAFIEEI
                     CMSVADFASQNNIQLTFDTEIEEFSMLFDSEKLERIILNLLSNGIKYNKKDGKINIFL
                     YVKDNVFNMKISDSGIGIPKEKIDKIFNRFEQIDNELSYRVKGSGIGLSLVKSLVELH
                     EGSISLKSQLGIGSEFIVSLPVRSKNNIEKYNHKREISNELSKKLEIEFSDL"
     misc_binding    1998..2238
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     misc_binding    2304..2539
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            2624..3841
                     /locus_tag="ACGI5H_002535"
     CDS             2624..3841
                     /locus_tag="ACGI5H_002535"
                     /EC_number="1.1.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420177.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004412 - homoserine dehydrogenase
                     activity [Evidence IEA];
                     GO_function: GO:0050661 - NADP binding [Evidence IEA];
                     GO_process: GO:0006520 - amino acid metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="homoserine dehydrogenase"
                     /protein_id="HFG9698235.1"
                     /translation="MENKVKIGVLGYGVVGSGLIDIIDNNKEKRNIEIVGILVNNLEK
                     HKDKKYSNIITNNIDDIFNKDIDILVEVMGGLEPSLSYIKKALNNKIHVVTANKDLLA
                     ECGDELAKLASENKVSIKFEASVAGGIPVLKPIIESLEGNNIDSINAILNGTTNFILS
                     KMYDENLSYDMALRQAQELGFAEANPESDVLGYDAARKLSILSTLAYDNRVYWKDVYL
                     EGITDIDEKDIEYAKKLNCKIKLIGQSKYENDKVSAFVRPVLVEKDNILARIDNEFNA
                     VIVNGDSVGEVSFVGKGAGSLATGSAVYSDVIDIIDNRVSSIDSFTKDKIQVNKIVRE
                     KCGALLRFKKCNKDEILNIVENCLVKFDILNDDDELAIMVYADSEYEINNSLCLIKDK
                     GYCEKMNKMLKIS"
     gene            3958..4440
                     /gene="cdeM"
                     /locus_tag="ACGI5H_002536"
     CDS             3958..4440
                     /gene="cdeM"
                     /locus_tag="ACGI5H_002536"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436550.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exosporium morphogenetic protein CdeM"
                     /protein_id="HFG9698236.1"
                     /translation="MENKKCYSEDWYERGESTAKWFQNDREEYEREAYDEDRERRGSN
                     CGCSDSGENRPRNCERFRREAEIREREAREAFCESSEKKKEALAYECEARKLWEEAEK
                     YWDEYSKYNYKGIEYLAEAARLFDEGMECEARRNGNNGGNNNNCCHKCHKCNCNCCRK
                     "
     gene            4704..5969
                     /gene="hisD"
                     /locus_tag="ACGI5H_002537"
     CDS             4704..5969
                     /gene="hisD"
                     /locus_tag="ACGI5H_002537"
                     /EC_number="1.1.1.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902633.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004399 - histidinol dehydrogenase
                     activity [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_function: GO:0051287 - NAD binding [Evidence IEA];
                     GO_process: GO:0000105 - L-histidine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="histidinol dehydrogenase"
                     /protein_id="HFG9698237.1"
                     /translation="MKSIKTSSMKEKVDEKILREQVSSIIEDIRNNKDVALKKYNEKF
                     DRNTRDEFRITKEEIKEAYKHVDDEFINNLKIAAKNIREFAKAQKLSFENPFEKEIYP
                     GVILGQTNIPIESCLAYVPGGQYPLFSTALMLIIPAKVAGVKRIVACSPTMKNTEKIN
                     PKTLVAMDIAGADEIYATGGVQAIAAFTYGTEKINPVDIIVGPGNKFVTEAKRQCYGQ
                     VGIDFVAGPSEVLIIADETSNPVYIAADLLAQCEHDLNARGILLTNSLEVAQKVEKNI
                     ESMLKDLPTKDIAYSSWENNGEIILVDDMEEAIKISNFYAPEHLEVAVNEYNDICDRL
                     TNYGSLFIGNLSAEVFGDYVSGTNHTLPTLKASRYTGGVWVGTFIKTCTKQIFNEKAI
                     QSLAPVAEKLAKEEGLYAHAKAAEVRFKK"
     gene            complement(6172..6924)
                     /locus_tag="ACGI5H_002538"
     CDS             complement(6172..6924)
                     /locus_tag="ACGI5H_002538"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861262.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HFG9698238.1"
                     /translation="MSYFQYQGNSCFYKEYGQGKPIIFLHGNTGSSNMFKALVPLYAE
                     NFRCILIDFLGNGQSDRVSQFSPDIWHDEALQTIALIEHLNCGKVGLIGTSGGAWAAV
                     NTGLERPDLVEAIIADSFDGRTLNDNFIDNLITGREKSKQDIQARKFYEWCHGKDWEN
                     VVNLDTKALLQCANEKRPLFHKELCKLEMPILFTGSKEDEMCRHNLEEEYKQMATFIS
                     KASIYIFSQGGHPAILTNADEFAQLAKVFFKY"
     gene            complement(7042..7311)
                     /locus_tag="ACGI5H_002539"
     CDS             complement(7042..7311)
                     /locus_tag="ACGI5H_002539"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436543.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CD3324 family protein"
                     /protein_id="HFG9698239.1"
                     /translation="MSYQNSIDLLPKELIEQVQEYIDGKVIYIPKKQEHKKHWGENTN
                     TKQVLASRNSQICINFQNGMSIKQLSEKYFLTEKSIQRILKQQNL"
     gene            7786..8880
                     /locus_tag="ACGI5H_002540"
     CDS             7786..8880
                     /locus_tag="ACGI5H_002540"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429999.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="HFG9698240.1"
                     /translation="MKNIVGKPQTIKKVNEDLIKNIIKNEGPITKPEISSITELSLAT
                     VNKIVEQLALKNEVKVSGLSESTGGRRAQLFEINANLEHIIALYYYRNCCIGVVANLL
                     GEIIYQEEFNIRMDTYENVNQDTFFVIDTLIKKEKGNNIRAIGIGVPGVVKKGVVKNI
                     PTIKSWEGINLENLIKSKYNTKVFIENDTNITTIGIYQKQYKDKYKNMALMYLEDGIG
                     SGIVINGELYLGSTNFAGELSYLNIEFGKYNSNNLNLEDYIMSLRKRYLESKDNKFKK
                     EILSIISNFIRTLVCVLNPQAMIIQCSILTKSDMEFIEKDVSNNVGEENFPKLIKVDS
                     LREGSINGVISMCLKETDYQYSLSNKKGGY"
     gene            8882..9832
                     /locus_tag="ACGI5H_002541"
     CDS             8882..9832
                     /locus_tag="ACGI5H_002541"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861264.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylglucosamine kinase"
                     /protein_id="HFG9698241.1"
                     /translation="MKYLVSIDGGGTKTKFCVSDLDGNILKEHTTGSTNYKSVGIKKT
                     YENINNGFKKILKDLYIDYDDIEYTVFGISGCDSPNDYKIIMDEILKIGINKEKIYLA
                     NDAVLAFYAQADSPGLVIVAGTGSIILGIKEDGEIYRVGGWGYNFSDLGSGYDIGRKL
                     LKKVLLYCDECHEYSDLFSCVLDFFGANSFEQLAYMITDINDNVEIANLASLVIDCAE
                     QGDKLAIEILRESSTELSKLAQVILRKISNPMKMDKSEINIVLSGGTLNKTVYAQMLM
                     NNLKTENTDKNLKFISQENQPVYGGIRLAMALANRRVKHG"
     gene            9825..11009
                     /locus_tag="ACGI5H_002542"
     CDS             9825..11009
                     /locus_tag="ACGI5H_002542"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9698242.1"
                     /translation="MDRKKVIVQIFTGGFKAKEIKFNDIKCKLLELLDCIDIEKVIMG
                     WSVDEELYVETKKLLNKYNVELYLWLPCFSEIGLLEKSNLLIDYMGKEVKGYALQEDE
                     NFEFYCPNNKENIKNIKKIYSTYFSDIKFDGIFLDKIRYGSFSNKLNGVFNCFCKDCL
                     NIYKKNNIDKESLMREMNNVSKGVIDNEDTPFGITEYINGKYKFKNKIWEDFFETKNQ
                     NIYKALLEISSYFKSKGLKIGIDAFSPFISYFTGQDLEKLQEVADFIKPMMYRTTKAP
                     AGLPFEFERFIDESIHKNKEIGKRNFLDILGIKEYEGDVYPIEFVLEEIDFMTRNLNK
                     DIYVGVEINKKEIISPVTPKYISENISNINKTTVKGYVLSWDLLSAPKENIDEIIKWF
                     RN"
     gene            11022..12518
                     /locus_tag="ACGI5H_002543"
     CDS             11022..12518
                     /locus_tag="ACGI5H_002543"
                     /EC_number="7.5.2.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902638.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter ATP-binding protein"
                     /protein_id="HFG9698243.1"
                     /translation="MSKILEIQQIYKSFGKVDVLKGINFELEKGEVRALLGANGAGKS
                     TLIKILGGVHSQTKGKVILTGNEIMFKNPHHSKENGISIIYQELSLIPTLTVLENIFL
                     GREILKGSVFLNKKDMLEEYMKICEDFDFNIDPHIVVSNLSVANQQMVEIMKAVSCNS
                     EIIIMDEPTTSLTNNEKDGLFKIISRLKSKGKTIVYISHILEEVFKVCDSASIMKNGI
                     MIGTYDVEDLTKLKITQLMTGNDNHKLIEKKDYTFAKYEEPPVLEVKNISWSNKIKNV
                     SFKVYRGEVVGLAGLVGSRRTEIINLIFGIDNKDSGDIFINGKKVDITSPKVAIKNKI
                     GLIPEDRKNLGLILEQAIYTNSSSVQIDKFKKFLFIDRNKEIEFSKKGVKELGIKVSD
                     VKQEVKELSGGNQQKVVVSKWLEKDLDLIIYDEPTKGIDIAAKEDIFNTIKEFSSKGI
                     GVIFISSDLEEVIRVSDRILVTREGSIVDDLKNENIQVQDIMNSIFNV"
     gene            12541..13491
                     /locus_tag="ACGI5H_002544"
     CDS             12541..13491
                     /locus_tag="ACGI5H_002544"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896747.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HFG9698244.1"
                     /translation="MKKAFEKLNLRDYGVLLGFLALCIAISIATPSFLGKQNILNLLR
                     QSSIIGIISAGMTFVIISGNFDISVGAVAALAGAITMKFATGGTNLFASMFLGVAICA
                     VIGLINGIVVAKINVPSLIATMAMVTIVRGLLLMLTGGYPITENIPILDYIGNGYLFN
                     IPIPVVIFFIVVLASFIVLNKTKFGRYVYSVGGNQEASKLNGINVDSHKVKVFIINAV
                     LAGIAGIVLTGRLGTATAIAGEGYDMDAIASVVIGGTSVAGGSGSVLKTVIGVLLMSV
                     INNSFNLLGIDVYFQYIFKGLIILAAVGFDSYSKKKLASR"
     gene            13512..14474
                     /locus_tag="ACGI5H_002545"
     CDS             13512..14474
                     /locus_tag="ACGI5H_002545"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430005.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter substrate-binding protein"
                     /protein_id="HFG9698245.1"
                     /translation="MKKLMKHLALLLSLVMIFGLVGCSNGGDKEKNGEKKIAVLLPGS
                     TGYFVATKQGIDAKSKELGVSVEYADAQWDASKQLSQAEDFMAKGVDMIALCGVDSAV
                     SERIVKAANDSDVPIVAFTNSIGSNPTGEFKGLVTYIGQNEEETGALTGKIAKNLLGE
                     TGGKAVLIEGVPGTTPQVLRKKGLEKELKDSNIEIVYNQTSNWEKEQALKVTEDLIQK
                     KTDFNVIICQDDNSATGAGQALKDAGLKDKVKVIGLGGSKDGLKAITDGLIDGTTYMS
                     AVEEGGLVIEKASKFLKGEKIEPVTQIKQVEVNKDNISEFKGEW"
     gene            14846..15478
                     /locus_tag="ACGI5H_002546"
     CDS             14846..15478
                     /locus_tag="ACGI5H_002546"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436524.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HFG9698246.1"
                     /translation="MARRLFLERIGLIFLGSAILAFGVYNFYYLNNITEGGVLGILLL
                     LKNLFNIQPAIANVVIDGLLLLVGYKFFGKKFLIYSIVASITFSVLYDLFEAIGPLVP
                     QSQNMLLSTILAGVTVGTGVGIVVKAGCASGGDDALALVISKTTSLNIGQVYLATDVI
                     VLLLSLFYLSAFDIFYSLIAVTISGKVIDFIYYHGKSLDMDISNDIVPEC"
     gene            15904..15981
                     /gene="kdpF"
                     /locus_tag="ACGI5H_002547"
     CDS             15904..15981
                     /gene="kdpF"
                     /locus_tag="ACGI5H_002547"
                     /EC_number="7.2.2.6"
                     /inference="COORDINATES: protein motif:HMM:TIGR02115.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0031004 - potassium ion-transporting
                     ATPase complex [Evidence IEA];
                     GO_process: GO:0006813 - potassium ion transport [Evidence
                     IEA];
                     GO_process: GO:0043462 - regulation of ATP-dependent
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="K(+)-transporting ATPase subunit F"
                     /protein_id="HFG9698247.1"
                     /translation="MWFLAVVIIMLIIYLVYALINPEKF"
     gene            16028..17704
                     /gene="kdpA"
                     /locus_tag="ACGI5H_002548"
     CDS             16028..17704
                     /gene="kdpA"
                     /locus_tag="ACGI5H_002548"
                     /EC_number="7.2.2.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436522.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0031004 - potassium ion-transporting
                     ATPase complex [Evidence IEA];
                     GO_function: GO:0008556 - P-type potassium transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0006813 - potassium ion transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="potassium-transporting ATPase subunit KdpA"
                     /protein_id="HFG9698248.1"
                     /translation="MVQIVIVLAIFMILVIPMGKYLYHIATNQKTFGDRLFDKVDNFI
                     YKVCSIDKKKEMNWKQYALALLFTNAVMVFIGYIILRTQSMHIFNPSGIKSMEQGLSF
                     NTIISFMTNTNLQHYSGESGLSYFSQMTVIIYMMFTSAATGYAAAMAFVRGLVGKKKT
                     LGNFYVDLIRITTRVLLPGALIIGLILVTQGVPQTFAGTETVTTIEGKLQDIARGPVA
                     ALESIKHLGTNGGGFFGSNSSHPFENPTIISNIVEILSMMILPGACVVAFGHMIKNKK
                     QGWVVFGAMSIIFLIGLVVCFKAESAGNPILSQLGLNQSMGSMEGKEVRFGIAQSSLF
                     TTVTTSFTTGTVNNMHDTLTPLGGLVPLLNMMLNVVFGGKGVGLMNMLMYAIIAVFLC
                     GLMVGRTPEFLTKKIEGKEMKLIALLIILHPLLILMFSGLSVAIPAGLEGISNPGFHG
                     LSQVLYEFASSAANNGSGFEGLGDNTMFWNITTGVVMFFGRYVSIIVLLAISSLLASK
                     KAVNESIGTLRTDNFTFTIVLVLVVLIVGALTFFPALALGPISEHLVLWH"
     gene            17729..19786
                     /gene="kdpB"
                     /locus_tag="ACGI5H_002549"
     CDS             17729..19786
                     /gene="kdpB"
                     /locus_tag="ACGI5H_002549"
                     /EC_number="7.2.2.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893173.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_component: GO:0031004 - potassium ion-transporting
                     ATPase complex [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0008556 - P-type potassium transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0006813 - potassium ion transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="potassium-transporting ATPase subunit KdpB"
                     /protein_id="HFG9698249.1"
                     /translation="METKKTKFITKDIFKTSIIEAFKKLNPKYMMKNPVMFVVEIGFI
                     VTLILTIVPSLFGDEGNNLRAYNGIVTIILFITVLFANFAEAVAEGRGKAQADTLKKT
                     RKDTVARVIDTLGNEKMISASELKLGDIVLVNAGEVIPNDGEVIEGIASVDESAITGE
                     SAPVMRESGGDFASVTGGTTVVSDWLKIRITTKPGESFLDKMIALVEGASRQKTPNEI
                     ALNTLLVGLTLIFMVVLISLYPMANYAGVKIPISTMIALLVCLIPTTIGGLLSAIGIA
                     GMDRVTRFNVIAMSGKAVEACGDVDTMILDKTGTITYGNRLASEFIAVGNADSKDLIN
                     YSVMCSLKDDTPEGKSIVDLGMKLGSTGKTKEAEEAEFVEFSAQTRMSGINLADGRAI
                     RKGAYDSIIKRVKESGGTVPEDLEENVNRVAKLGGTPLVVCVDNEIYGIIYLKDTVKS
                     GLVERFARLREIGIKTIMCTGDNPLTAATIAREAGVDGFIAECKPEDKIDAIKKEQLE
                     GKIVAMTGDGTNDAPALAQADVGLAMNSGTTSAKEAANMVDLDSDPTKILEVVEIGKQ
                     LLITRGALTTFSIANDVAKYFAIIPAIFTLAIPQMEILNVMKLSTSFSAILSALIFNA
                     IIIPCLIPLAMKGVKYRPMKSQAMLMRNMLIFGLGGVIVPFLGIKLIDLLITPLVMVL
                     NLG"
     gene            19805..20431
                     /locus_tag="ACGI5H_002550"
     CDS             19805..20431
                     /locus_tag="ACGI5H_002550"
                     /EC_number="7.2.2.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902640.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="K(+)-transporting ATPase subunit C"
                     /protein_id="HFG9698250.1"
                     /translation="MKTLKPALLVSIVLLVVCGLVYPLVLTGVSQVAFKDKANGSMIE
                     VNGVKVGSELIGQSFTDARFFKGRVSSVNYNTYTKEDLVPDKDGNTSYGGVSSGSFNY
                     GATNPELHDRVQKDIEKFLKDNPTVKREDIPTDLLTASGSGLDPNISPASAKIQIPAI
                     AKASGISESKLQKIVDDNTSKKLFGVLGEDRVNVLKVNVEVAKILGLI"
     gene            20668..21576
                     /gene="cysK"
                     /locus_tag="ACGI5H_002551"
     CDS             20668..21576
                     /gene="cysK"
                     /locus_tag="ACGI5H_002551"
                     /EC_number="2.5.1.47"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902642.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004124 - cysteine synthase activity
                     [Evidence IEA];
                     GO_process: GO:0006535 - cysteine biosynthetic process
                     from serine [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine synthase A"
                     /protein_id="HFG9698251.1"
                     /translation="MLYNNALELIGNTPVVRLNNLGCTNGCSNIYVKLEKVNPAGSIK
                     DRAVYEMLEGLEQRGELKKGDVLVEATSGNTGIALSMIGKLKGYEVVIVMPETMSVER
                     RDLMKAYGANLVLTDGKAGMAGSIEKANELLKENPNYKSLKQFENKDNPNAHYKTTAV
                     EIMNDVKDLDIFVCGVGTGGTLIGTARYLKEQNPNIRVIALEPKKSPAISENKTGPHK
                     IQGIGANFVPENYDSSVVDEVILVDDEDAFDTVKLLAAKEGILVGISSGANIFGAIEM
                     AKKYPDKKIVTVAPDGVDKYMSMGIF"
     gene            21603..22193
                     /gene="epsC"
                     /locus_tag="ACGI5H_002552"
     CDS             21603..22193
                     /gene="epsC"
                     /locus_tag="ACGI5H_002552"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905512.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0009001 - serine O-acetyltransferase
                     activity [Evidence IEA];
                     GO_process: GO:0006535 - cysteine biosynthetic process
                     from serine [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="serine O-acetyltransferase EpsC"
                     /protein_id="HFG9698252.1"
                     /translation="MFKKINKDIEYIMKNDPAARSKIEVFLLYPSVHAMIMHRMAHAL
                     YKKKKLFTARLISQISRFMTGIEIHPGAKMGEGILIDHGMGVVIGETAEVGNRVTIYQ
                     GATLGATGKDTGKRHPTVGDDVLIGAGTKILGPLNIGSNSKIGANSVVVKDVPNGATV
                     VGIPAKIVKIRNLEPVKKNKKEVSYEYDELDNVYYI"
     gene            22353..22541
                     /locus_tag="ACGI5H_002553"
     CDS             22353..22541
                     /locus_tag="ACGI5H_002553"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420199.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005506 - iron ion binding [Evidence IEA];
                     GO_function: GO:0009055 - electron transfer activity
                     [Evidence IEA];
                     GO_function: GO:0051539 - 4 iron, 4 sulfur cluster binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ferredoxin"
                     /protein_id="HFG9698253.1"
                     /translation="MKANVNQDTCIGCGLCPSICPEVFDMKDDGKSHVIVDEVPSDAE
                     ESAAEARESCPVDAIDVH"
     gene            complement(22595..23464)
                     /locus_tag="ACGI5H_002554"
     CDS             complement(22595..23464)
                     /locus_tag="ACGI5H_002554"
                     /EC_number="3.4.11.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420201.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionyl aminopeptidase"
                     /protein_id="HFG9698254.1"
                     /translation="MKLNRNDSCWCGSTKKYKKCHMDMDNKIDSFAKLGHIVPTHDII
                     KNESQIEEIKKSAVINTKILDYISDKIEIGMSTEDINKLVHDFTLQNGAIPAPLDYNG
                     FPKSVCTSVNNEVCHGIPSKDIILKDGDIINVDVSTIFNGYYSDASRMFMIGNVNENA
                     KKLVQVTKECVQKGLEVAKPWGFLGDIGDAINSYAKKNGYSVVREIGGHGVGLSFHED
                     PFVSYVSKKGTEMLLVPGMIFTIEPMVNEGTHEIFVDEENNWTIYTKDGKLSAQWECM
                     VLVTETGVEILTE"
     gene            complement(23661..24905)
                     /locus_tag="ACGI5H_002555"
     CDS             complement(23661..24905)
                     /locus_tag="ACGI5H_002555"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902644.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9698255.1"
                     /translation="MENNLNTAKRNNTELLQNDSLKVNLQIGVDFTLLSKSLKAFYKK
                     EKDFYCIALAPCNVSSEKANRKISIYDMIKEINILIESITDKNELLSEELFTNNLSEF
                     YDESLDEIYIDLKQAYLYIKKNTDGLNIEDSIEYVFDVDISNDIKAKENPLINFNSLS
                     LVVWSGETKHILQQMNILDLEDIHSYSIENNTNITIYENNTLQYKFDEESENIKDSSI
                     DIIEQMLILPDDLNYDKDEVENMKNRLAKINIKYLQTLKEKDIKIKLINSNLTDEPEF
                     SDLKYQLPPCWVRSGKTWKDVPGIYRNNSIVAKIGYSNPSYANVHSSKNLELHETAHA
                     IDKNVLNKKSNSEEFMEVFAQERYKLYDPKQVAHAYISKFIEEFFAESFVHYYLDEDS
                     KNTLKENCPLTYDFLEKLELNY"
BASE COUNT         9623 a         2674 c         4505 g         8176 t
ORIGIN      
        1 tcatataatt aattaagtag tattattata aataacattg aaaggtagtg gttagaatat
       61 ggatacccat aataaatatg taaattttat aaaaaatata cctgtacctt ttttatattg
      121 tagaattgta aagagacaag aagatataga atatcgagta gaatatataa gtaagggtat
      181 gggcaaagta ttacaattag aagaaggtat ttgtgataaa aatatactag atgtattgcc
      241 tgtatttaag tctaaaaaat atttcaaaga gttgttctca aatgaagtgg attgtataaa
      301 aaggtacatt ccgacactta aaaattggat aaatataaaa aaacagataa taggggattc
      361 atacataatt ttgtattttg gtaaaattgt atttgattat agacagataa tcgattcctt
      421 tgataaaaag gaaaaagtag cttatattaa agacgaagaa ggcacatata tagattgcag
      481 tgaaaattta ataccaatat taaataacaa cattaaaaca acgaaagata tctttggtaa
      541 aaatgatata gaagtatggg gagagaatac aggaaaatta tttagagatg attatagaga
      601 aggagtatct agtaaaaaaa gatttttaca aaatcttttt gaatatgaag aaacattttt
      661 tatggttgaa aaatattttt tgtatgatga agacgaactt ttaggtacta tagggatagt
      721 agacaatata atatatagtg gttacagtaa tagaaattat aactcaaaag atttaatgaa
      781 gatgatagaa cactcaattc cagagaatat gttttataaa gatgtgtatg gaaattatat
      841 tggatttaat tcaggttttt tgaatttagc ttgtatgaat aaagaagaat tattagggaa
      901 gaatagttat aaaatatcag aagaagaagc tttaatagat aagatatttg aaagtgataa
      961 gggtgtagtt gaaaataaaa aagtagttac atttgagtta aatataagta tgaatgatga
     1021 aaacaagtgt attgagatta caaaaaggcc gttttttgat agctatggaa gtgttattgg
     1081 aataattgga acagcaaggg atataagtag aagaaaaaga ttagaagagg aaatggataa
     1141 aactaggatg gaattttttg caaatttatc ccatgaactt agaacgccta taaacttaat
     1201 atcatcttca ttacaagtga tagaaaaaaa agaagcagat ttaatagaat caaatgatac
     1261 tttaaaaaga aatttaggta taataaaaca aaatggaaat agaatattaa gattagtaaa
     1321 taatgttata gattttacaa aaatgcaatc aggatattta gattttaaac cagaagaatc
     1381 tgatataatt gcatttatag aggagatatg tatgtctgta gctgattttg caagccaaaa
     1441 taatatacaa cttacatttg atacagaaat agaagaattt tcaatgttat ttgattcaga
     1501 aaaattggaa agaataatat taaatttact ttctaatgga attaagtaca ataagaaaga
     1561 tggaaaaata aatatatttt tatatgtgaa agataatgta tttaatatga aaatatctga
     1621 tagtggaata ggaataccaa aagaaaaaat agataaaata tttaataggt ttgaacagat
     1681 tgacaatgaa ctttcttaca gagttaaagg aagtggtatt ggactttcat tagtgaaatc
     1741 tttggttgag ttgcatgagg gaagtatatc tttaaaaagt caacttggta ttggaagtga
     1801 atttatagtt tcattgcctg ttagaagtaa aaataatatt gaaaaatata atcataaaag
     1861 agaaatcagc aatgaattaa gtaaaaaatt agaaatagag ttctcggatt tataagttta
     1921 aatataaaaa ataaaatttt aaaaaagtat tgacaattga tttagaaggg tttaaaataa
     1981 attacaacat aataaataaa aaggcgatga ataggaagag taaatctaat tcgattacca
     2041 gagagaagag tccgttggct ggaagacttt ttaaattaga gggattgaaa actacctagg
     2101 agctactttc tgaagtcatc tgcattagta gattttagta agaatagtcg ttagctgcgt
     2161 taaagtgtaa agtgagtttt catgacatat gaaaactaaa ttaggtggaa ccgcgggaat
     2221 aatactctcg tccttatgtt ataaggatga gagttttttg ttatttaaaa atataaacag
     2281 taatcataat aattatagaa aatataaaag caatgaatag gaagagtaaa tttaattcga
     2341 ctatcagaga ggaaagttca caggctgaaa gactttctaa gtttgagaaa ttgaaaacta
     2401 cctaggagct gtggtctgaa gttactttaa aaagttttag taagactaac cgttaactgc
     2461 gttaaagtgt aaagtggatt ttatcaataa atgataaaat caaattgggt ggaaccgcga
     2521 gtatagactc gtccctttat atagggatga gtctattttt attgcaataa aagattgaaa
     2581 ataaaaaaaa atcggaaaat tataaattta ggaggaaaat aaaatggaga ataaagtgaa
     2641 aattggagta ctaggatatg gagttgtagg aagtggactt atagatataa tagataataa
     2701 taaagaaaaa agaaatatag aaatagttgg aattttagtt aataatttgg aaaaacataa
     2761 ggataaaaaa tattctaata taataactaa taatatagat gatatattta ataaagatat
     2821 agatatactt gttgaagtca tgggtggttt agaaccatca ttatcttata taaaaaaagc
     2881 attaaacaat aaaattcatg ttgttacagc aaataaagat ttgttagctg aatgtggaga
     2941 tgagcttgca aaattagcaa gtgaaaataa agtaagtatt aaatttgaag cttcagttgc
     3001 aggaggtata ccagtattaa aaccaataat agaatcacta gaaggaaata atatagatag
     3061 tataaatgca attttaaatg gaactactaa ttttatatta tctaaaatgt atgatgagaa
     3121 tctatcttat gatatggcat taagacaagc acaagaatta ggttttgctg aagcaaatcc
     3181 agagtcagat gtattagggt atgatgctgc tagaaaacta tcaatattat caactctagc
     3241 ttatgacaat agagtatatt ggaaagatgt gtatttagaa ggaattacag atatagatga
     3301 aaaagatatt gaatatgcaa aaaaattaaa ttgtaaaata aaattgattg gtcaaagtaa
     3361 gtatgaaaat gataaagtaa gtgcttttgt tagacctgtt ttagtagaaa aagataatat
     3421 ccttgctaga atagacaatg agttcaatgc tgtcatagtg aatggagatt cagtaggaga
     3481 agtttctttt gtaggtaaag gagctggaag tttagcaaca ggaagtgcgg tttattcaga
     3541 tgttatagat ataatagata atagagtttc aagtatagat tcttttacta aagataaaat
     3601 acaagttaat aaaatagtta gagaaaagtg tggagcactt cttagattta aaaaatgtaa
     3661 taaagatgaa attctaaata tagttgagaa ttgtttagta aaattcgata ttttaaatga
     3721 tgatgatgaa cttgctatta tggtttatgc tgattctgaa tatgaaataa acaacagttt
     3781 atgtctaata aaagataaag gatactgcga aaaaatgaat aaaatgttga aaataagtta
     3841 aaaaagaaaa aatataagtt tatatgtaac atattttgac gattttaata ctatatagta
     3901 tgagatgaaa caaaacatct cataaaaaaa ttaaaattaa agggagagat atgttatatg
     3961 gaaaataaaa aatgttattc agaagattgg tatgaaagag gagaatctac agctaaatgg
     4021 ttccaaaatg atagagaaga atatgaaaga gaagcatatg atgaagatag agaaagaaga
     4081 ggttcaaact gtggatgttc agattcagga gaaaatagac ctagaaactg tgaaagattt
     4141 agaagagaag ctgagataag agaaagagaa gcaagagaag cattctgtga atcttcagag
     4201 aaaaagaaag aggcattagc atatgaatgt gaagctagaa aattatggga agaagcagaa
     4261 aaatactggg atgaatattc aaaatacaac tataaaggaa tcgaatattt agcagaagct
     4321 gctagattat ttgatgaagg tatggaatgt gaagctagaa gaaatggaaa taatggagga
     4381 aacaataata attgttgcca taaatgccat aaatgtaatt gtaactgctg tagaaaataa
     4441 aaaaattaat tgacaaatca atagttaaaa tatatcatat tatgtataat aaagagaaaa
     4501 ttcagaaaaa aataatgatt agaagaaata taagtatatt tattagacaa atagtgctca
     4561 gttagtgagg tgagtacaat atgattaaac tcccatcctc tagcttttga tagagggtgg
     4621 gagtttttat ttatttatat atcttaaatg aggataatat tgtaaaataa atgagtatga
     4681 gattgtaaaa ttaggaggta aaaatgaaaa gtattaaaac atcaagtatg aaagaaaagg
     4741 tagatgaaaa gatattaaga gagcaagtaa gttctataat agaagatata agaaataata
     4801 aggatgttgc acttaaaaaa tataatgaga agtttgatag aaatacaaga gatgaattta
     4861 gaattactaa ggaagaaata aaggaagctt ataagcatgt agatgacgaa tttataaata
     4921 acttaaagat tgctgccaaa aatataagag aatttgctaa agctcaaaaa ctaagttttg
     4981 aaaacccttt tgaaaaagaa atttatccag gtgtaatctt aggtcaaact aatattccaa
     5041 tagagtcatg tcttgcatat gttccaggag gtcagtatcc attgttttca acagctctta
     5101 tgcttataat acctgcaaaa gtagcaggag taaaaagaat agtggcatgt tcaccaacta
     5161 tgaaaaatac tgaaaagata aatcctaaga cattggtagc tatggatata gcaggtgctg
     5221 atgaaatata tgcaactgga ggagttcaag ctatagcagc atttacatat ggaacagaaa
     5281 agattaatcc agttgacata attgtaggac caggaaataa gtttgtaact gaagctaaaa
     5341 gacaatgtta tggacaagta gggattgatt ttgtcgctgg gccaagtgaa gttcttataa
     5401 tagcggatga aacttcaaat ccagtttata ttgcagctga tttattagca caatgtgagc
     5461 atgatttaaa tgcaagagga atattattga caaatagctt ggaagtagca caaaaagttg
     5521 aaaaaaatat agaaagtatg ctaaaagatt tgccaacaaa ggacatagca tatagttcat
     5581 gggaaaataa tggagagata atattggttg atgatatgga agaagccatt aaaataagta
     5641 atttttatgc accagaacat ttagaagttg cagtaaatga gtataatgat atttgtgata
     5701 gattaactaa ctatggttct ttatttattg gaaatctttc tgctgaggtg tttggtgact
     5761 atgtttcagg taccaatcat acattaccaa cacttaaagc atcaagatat actggtggtg
     5821 tttgggttgg aacttttatc aaaacttgta caaagcagat atttaatgaa aaagctatac
     5881 aatcattagc acctgtagct gaaaagctgg caaaagaaga gggattatat gcacatgcaa
     5941 aggctgctga ggttaggttt aaaaagtagt aaaaaatttt attttggcag tcgagactta
     6001 gtattagact gagataagga aaacgctgag aacctgaata aatactatat tttgtgggtc
     6061 tcggcgcttc ttttatatct gtatataata gaataatact atctgtgtgt ttaaatacta
     6121 acttaatatt tcttttctaa ataatgttta tgaaatagtt aatattttta gttaatactt
     6181 gaaaaaaact tttgctaact gtgcaaattc atctgcattt gtcaatatag cagggtgtcc
     6241 tccctgacta aaaatgtaaa tacttgcttt tgaaataaaa gttgccattt gcttgtactc
     6301 ttcttcaaga ttatgacgac acatttcgtc ttccttactt cctgtaaata aaattggcat
     6361 ttctaattta cacaattctt tatgaaacaa agggcgtttc tcgtttgcac attgcaatag
     6421 agcttttgta tcaagattaa caacattctc ccaatctttt ccatgacacc attcatagaa
     6481 ttttcgtgct tgaatatctt gctttgattt ttcccttcca gtgattagat tatctatgaa
     6541 gttatcatta agagtacgtc catcaaagct atctgctata attgcttcaa ctaaatcggg
     6601 acgttctaat ccagtattaa cagctgccca tgctcctcca cttgttccaa ttaagccaac
     6661 tttaccacaa ttcaaatgtt caatcagtgc tattgtctgt aaggcttcat catgccatat
     6721 gtcaggagaa aattgagaaa ctctatccga ctgtccatta cctaaaaaat caattaagat
     6781 acatctaaaa ttttctgcat ataatggcac aagtgcttta aacatattag aagaaccagt
     6841 attaccatgc aggaaaatta tcggtttacc ttgtccatat tctttataaa aacaagaatt
     6901 accttgatac tgaaaatatg acatatattt tcctcctttt tatttgttaa gttaattata
     6961 acaatatagg tatgaatgaa aaacctcatg ttctttctta gaataaaaat gtgccacgca
     7021 taaaacgtga cacatttcta attataaatt ttgctgttta agtattcttt gtatgctttt
     7081 ctctgtcaaa aagtatttct ctgataactg cttgatactc attccatttt ggaaatttat
     7141 acagatttga gaattacgag aagctaagac ttgtttggtg tttgtgtttt caccccaatg
     7201 ctttttgtgc tcttgctttt tgggaatata aatcacttta ccatctatat attcttgcac
     7261 ttgctcaatc agttctttag gcagtaagtc aatcgaattt tgatagctca ttttgcacct
     7321 cctaaataat tattctttag gattagcaaa ggctactgcc actcacaatt aaaaataaaa
     7381 ttttttatta tgtacaatag cctttgctat gcacaagttc caattcccat aaactaaata
     7441 ctcctttctg gtttgaaaaa ttcatctgaa cattgatttc gcttttaaga tagagttcaa
     7501 tgacaaattt acatttttat tatatatatt cagatagata attgcaactg tctttgtatg
     7561 aggatatttt attatagtca atactataat atgtatttat atcatcaaac taatatgaac
     7621 agttgaaagg aatatgaaca ataaaactta gtcaggaaga ataattatga agcagacaat
     7681 agagaaattt gattttaaag ttttattgaa aatttattga caaatttaac ttgtaaatat
     7741 tatactaaac ttaataaata aagtttataa agtaaggtgt tgtctatgaa aaatatagtt
     7801 ggaaaaccgc aaacgataaa aaaagtaaat gaagatttaa taaaaaacat tataaaaaat
     7861 gaaggtccta taacaaaacc agaaatttca agcattactg aattgagttt agctacagtt
     7921 aataagattg tagagcaatt agctttgaaa aatgaagtta aagtaagtgg actaagtgaa
     7981 tctactggag gaagaagagc tcaattattt gaaataaatg caaacttaga acacataata
     8041 gctttatatt attatagaaa ttgttgtata ggggtagttg ccaatttatt aggtgaaata
     8101 atttatcaag aagaatttaa tataagaatg gatacgtatg aaaacgttaa ccaagatact
     8161 ttttttgtta tagatactct aataaaaaag gaaaaaggaa acaatataag ggctattgga
     8221 attggtgtcc caggagttgt aaaaaaaggt gtagttaaaa atataccaac tataaaaagt
     8281 tgggaaggta taaatttaga aaatttaata aagagtaaat acaatactaa agtgtttata
     8341 gaaaatgata caaatattac tactattggg atttatcaaa aacagtataa agacaaatat
     8401 aaaaatatgg ctcttatgta tttagaagat ggtattggtt caggtatagt tataaatggt
     8461 gaattgtatt taggttctac aaattttgct ggagaattaa gttatctaaa tatagaattt
     8521 ggtaagtata actctaacaa cttaaatctt gaagattata ttatgagttt aagaaaaaga
     8581 tatttagaaa gtaaagataa taaatttaag aaagaaattt tatctataat atcaaacttt
     8641 ataaggactc ttgtatgtgt cctaaatcca caagctatga ttatacagtg tagtatatta
     8701 accaagagtg acatggagtt tatagaaaaa gatgtaagca ataatgttgg agaagaaaat
     8761 tttcctaaat taataaaagt agactcattg agagaaggaa gtataaatgg agtaattagt
     8821 atgtgtttaa aagaaactga ctatcaatat tccttatcta ataaaaaagg aggatattaa
     8881 tgtgaaatat ttggtttcaa tagatggagg gggaacaaaa actaaatttt gtgtaagtga
     8941 cttagatgga aacatactta aagaacatac cactggttca actaattata agtcagttgg
     9001 aattaaaaaa acatatgaaa atattaataa tggatttaaa aaaatattaa aagatttata
     9061 tatcgattat gacgatattg agtacactgt atttggtata tctggttgtg attctcctaa
     9121 tgattataag attataatgg atgaaatatt aaaaattggg attaacaaag aaaaaatata
     9181 tctggcaaat gatgcagttt tagcttttta tgcacaagct gattcccctg gcttagtaat
     9241 tgtggctggg acaggttcaa ttatactggg aattaaagaa gatggagaaa tatatagagt
     9301 tggtggatgg gggtataatt ttagtgattt gggttctgga tatgatatag ggagaaaatt
     9361 attaaagaaa gtattgcttt attgtgatga atgtcatgag tatagtgatt tatttagttg
     9421 tgtcttggac ttctttggag caaatagttt tgaacaactt gcatatatga ttactgatat
     9481 aaatgataat gttgaaatag caaacttagc ttcattagtg attgattgtg ccgaacaagg
     9541 tgataaattg gctattgaaa tattaagaga atcatcaact gaactatcta aattagctca
     9601 agtaatattg agaaaaatat ctaatccaat gaaaatggat aaaagcgaaa taaatatagt
     9661 tttgtctggt ggtacattaa ataaaactgt atatgctcaa atgttaatga ataatttaaa
     9721 aacagaaaat acagataaaa atttaaaatt tatatctcaa gaaaatcagc cagtatatgg
     9781 ggggataaga cttgctatgg cattagctaa taggagggtc aagcatggat agaaaaaagg
     9841 taatagtaca aatttttact ggaggtttta aggctaaaga aataaagttt aatgatataa
     9901 aatgtaaact actagaatta ttggactgta ttgatataga aaaggttatc atgggatgga
     9961 gtgtagatga agaattatat gtagaaacta aaaaactatt aaataaatat aatgttgaac
    10021 tatatctttg gttgccatgt ttttctgaaa taggattact tgaaaaaagt aatttactaa
    10081 ttgattatat ggggaaggaa gtcaagggct atgctttaca agaggatgaa aattttgagt
    10141 tttattgccc aaataataag gaaaatataa aaaatataaa gaaaatatat agtacttatt
    10201 ttagtgatat taaatttgat ggaatttttt tagataaaat aaggtatggt tctttttcga
    10261 ataaactaaa tggtgttttt aattgttttt gtaaagattg tttaaatata tataaaaaaa
    10321 ataatattga taaagagtcg ttaatgagag aaatgaataa tgtgtctaag ggagttatag
    10381 ataatgaaga tactccattt ggtataacag aatacattaa tggaaaatac aaatttaaaa
    10441 ataaaatatg ggaagatttt tttgaaacaa aaaatcaaaa tatatacaag gcattattag
    10501 agataagtag ttattttaaa agtaagggat tgaaaatagg tatagatgct ttttctcctt
    10561 ttatttctta ctttacaggt caagatttag aaaaattaca agaagtagca gattttataa
    10621 aaccaatgat gtatagaact acaaaagctc cagctggttt accatttgaa tttgaaaggt
    10681 ttattgatga atccatacat aagaataaag agattggaaa aagaaatttc ttagatattt
    10741 taggaattaa ggagtatgaa ggagatgtat atcctataga atttgtacta gaggaaatcg
    10801 attttatgac aagaaatctt aataaagata tatatgtagg agttgaaata aataaaaagg
    10861 aaattatatc tcctgttaca cctaagtaca taagtgaaaa tatttcaaat ataaataaga
    10921 caacagtaaa aggatatgtt ttatcttggg atttgttgtc agcaccaaaa gaaaatattg
    10981 atgaaattat aaaatggttt cggaattagt gaggtgataa agtgagtaag atattggaaa
    11041 tacaacaaat atataaaagt tttggaaagg tagatgtttt aaaagggata aattttgagt
    11101 tagaaaaggg agaagtaaga gctcttttgg gagctaatgg agcaggaaaa tctacactta
    11161 ttaaaatttt aggaggagtt cattctcaaa ctaaaggtaa agtaattttg actggtaatg
    11221 aaataatgtt taaaaatcca catcattcta aagaaaatgg tattagtata atttatcaag
    11281 aattaagctt gataccaacg cttacagtac ttgaaaatat ttttcttggt agagaaattt
    11341 taaaaggaag tgtgttttta aacaagaaag acatgcttga ggaatatatg aaaatttgtg
    11401 aggattttga ttttaatata gacccacata tagtagtttc taatttaagt gtagcaaacc
    11461 aacaaatggt tgagataatg aaagctgttt catgtaattc tgaaattatc ataatggatg
    11521 aacctacaac atcacttact aataatgaaa aagatgggct atttaaaata ataagtagac
    11581 taaagtctaa aggtaaaaca atagtctata tttctcacat attagaggaa gtttttaaag
    11641 tatgtgatag tgcaagtata atgaaaaatg gaattatgat tggaacttat gatgtagagg
    11701 atttaactaa attaaagata actcaactta tgacaggaaa tgataatcac aaacttattg
    11761 agaagaagga ttatacattt gcaaaatatg aagagccacc agtactagaa gtaaagaata
    11821 taagctggtc taacaaaata aaaaatgttt catttaaagt ttatagaggc gaagttgtag
    11881 gtcttgcagg tcttgtaggt tcaagaagaa ctgaaattat aaatttgata tttggtatag
    11941 ataataaaga tagtggagat atttttatca atggtaaaaa agtagacata acttctccta
    12001 aggttgctat aaaaaacaaa ataggattga ttcctgaaga tagaaaaaat ctaggattaa
    12061 ttttagaaca agctatatac acaaactcat catcagtaca aattgataaa ttcaagaaat
    12121 ttttgtttat agatagaaat aaagaaattg agttttctaa aaaaggtgtt aaggaattag
    12181 gaataaaagt tagtgatgta aagcaagaag taaaagagct tagtggtgga aatcaacaaa
    12241 aagtagtagt ttctaagtgg ttagagaaag atttagattt aataatatat gatgagccga
    12301 caaagggaat agatattgct gcaaaagaag atattttcaa tacaatcaaa gaattttcaa
    12361 gtaaaggaat aggagtaata tttatatctt ctgatttaga agaagtaata agagtaagtg
    12421 atagaatttt agtaactaga gaaggttcta ttgtagatga tttaaaaaat gagaatatac
    12481 aggttcaaga tataatgaac agtatattta atgtataaaa aatgaaaatg gaggactgag
    12541 atgaagaaag cttttgagaa gttaaattta agagattatg gagtattatt aggtttttta
    12601 gctttatgta tagctataag tattgcaact ccatcatttt taggtaaaca aaatatactt
    12661 aatcttttac gacaatcttc tataattgga ataatttcag caggtatgac ttttgttata
    12721 atatctggaa actttgatat atcagttgga gcagtagcag ctcttgcagg tgctataaca
    12781 atgaaatttg cgactggtgg aactaatttg tttgcatcca tgttcttagg tgtagcgatt
    12841 tgtgcagtaa taggattaat caatggtata gtagttgcaa agataaatgt accatcatta
    12901 atagccacta tggctatggt cactattgta agaggattgc tgttgatgct tacaggagga
    12961 tatccaatta ctgaaaatat accaatactt gattacattg gaaatggata tttgtttaat
    13021 ataccaatac cagtagtaat tttctttata gtggtgttag cttcgtttat tgtacttaat
    13081 aaaactaagt ttggtagata tgtttattct gtaggaggga atcaagaagc aagtaaactt
    13141 aatggtataa atgtagattc tcacaaagtg aaagtgttta ttattaatgc tgtacttgca
    13201 ggaatagctg gaatcgtact aacaggaaga cttgggactg caactgcgat tgcaggtgaa
    13261 ggatatgata tggatgcaat tgcatctgta gtaataggag gtacatcagt ggcaggaggt
    13321 tctggttctg tacttaaaac tgttatagga gtattactta tgagtgttat aaacaacagt
    13381 tttaatcttc ttggaataga tgtatatttc cagtacatat ttaaaggatt aataatttta
    13441 gcagcagttg gatttgattc ttatagcaag aaaaaacttg cttcaagata aaaaataagg
    13501 gggatttttt tatgaaaaaa ttaatgaaac atttagcatt gttgctatca cttgttatga
    13561 tatttggttt agttggttgt tcaaatggtg gtgacaaaga aaaaaatgga gaaaagaaaa
    13621 tagcagtatt actaccaggt tcaacaggtt actttgtagc aactaaacaa ggtatagatg
    13681 caaaatctaa agaattaggt gtaagcgttg aatatgcaga tgctcaatgg gatgctagta
    13741 aacaattatc acaagctgaa gattttatgg ctaaaggggt agacatgatt gcattatgtg
    13801 gagttgattc tgctgtaagt gagagaatag ttaaagctgc taatgattca gacgttccta
    13861 tagtagcatt tacaaattct ataggaagta acccaactgg agaatttaaa ggtttagtta
    13921 catatatagg acaaaatgag gaagaaacag gagcattaac tggaaaaatt gctaaaaact
    13981 tattaggaga aactggtggg aaagctgtat taatagaagg agtaccagga actactccac
    14041 aagtattaag aaaaaaaggt cttgaaaaag aattaaaaga tagtaatata gaaatagttt
    14101 ataatcaaac ttcaaattgg gagaaagagc aagctttaaa agtaacagaa gatttaattc
    14161 aaaagaaaac tgattttaat gttataatat gtcaagatga taattctgct acaggtgcag
    14221 gtcaagcttt aaaagatgct ggtcttaagg ataaagttaa agtcataggt ttgggtggaa
    14281 gtaaagatgg attaaaagct ataactgatg ggttaataga tggtacaact tatatgtctg
    14341 ctgtagaaga aggtggatta gtcatagaaa aggcatctaa attccttaaa ggtgaaaaaa
    14401 tagaacctgt tacacaaatt aaacaagttg aagttaacaa agataatatt tcagagttca
    14461 agggtgaatg gtaaattgtc atagataata aataagattt ttagagttac tttagaaact
    14521 atataaagta actctttttt taatttaatt tagtgataaa ttattgaata gtatttctaa
    14581 acaaataaaa aattaatata aacaaagact taattatact aaattataag taaaactaat
    14641 ataaacttat ggaaaaaagg aaaacgtcta aagtattgga attactatag tgtaggtgta
    14701 gtattaaaaa aacataaaaa aacataaaaa aattgttgaa aaaaatatag aaattttgta
    14761 taattaaaga tttgaaaagt gcggtataca aagccaattc ttttgtatat aatatatata
    14821 aattcagaaa aaggaaggga tatgtatggc caggcggtta tttttagaaa ggattggact
    14881 tatattttta ggttcagcaa tattagcatt tggagtttat aatttttatt atttaaacaa
    14941 cataacagaa ggtggagtgt taggtatttt actactgtta aaaaatttat tcaatataca
    15001 accagcaata gcaaatgttg taatagatgg tttactactt ttagtaggat ataaattttt
    15061 cggtaaaaaa ttccttatat attcaatagt agcttctata actttttcag tgttatatga
    15121 cttatttgaa gctataggac ctctagtacc acaatcacaa aatatgcttt tatcaactat
    15181 tttggcaggt gtaactgttg gaactggtgt aggtatagta gtaaaagcag gttgtgcatc
    15241 aggaggagac gatgctttag cattagtaat ttctaagact acatctttga acatagggca
    15301 agtttattta gcaacagatg ttattgtatt gttgttatca ttattttatc tatcagcgtt
    15361 tgatatcttt tattctttga ttgctgttac aattagtggc aaggtaattg attttattta
    15421 ttatcatggt aaaagtttgg atatggatat aagtaatgat atagttccag aatgttaata
    15481 taaattaaat aactttagat tttattaggg gtggcagatt tgccaccttt tttgtgtcta
    15541 aatctttata gaaagtataa tcccatctag gtttttgcaa atctcaaata tagaattatg
    15601 ttggaatgac tgggaatacg attgctagat gtgcatttta aaaacccaat tttatattta
    15661 tgaaatacta atcattaatg gatgtttctt aatcctatct ttatacctaa aatgataaga
    15721 taaatgaagt agcaatacaa aactaaaatt tgtaaaagag attaaattaa atggaggagc
    15781 taaaatgttg gatatagtta tgatagcatt gttattcata ggatttgttt ccatgaagtt
    15841 acttgctgat tggtgtggga aacaaactga aaaaaaataa tgtaatgtat ggagggatta
    15901 cctatgtggt ttctggcagt tgtaattata atgttaataa tatatttggt atatgcgctt
    15961 attaatcctg aaaaatttta aacagtataa ggctaataag taagttgaat tggggggaac
    16021 aatttttatg gtgcagatag taatagtgtt agcgattttt atgattttag taatacctat
    16081 gggcaagtat ttatatcata tagctactaa tcaaaaaaca tttggagata gactatttga
    16141 taaagtggac aattttatat ataaggtatg tagtatagat aagaaaaaag aaatgaactg
    16201 gaaacagtat gcattagctt tattatttac aaatgcagtt atggtattta taggatatat
    16261 catacttaga actcaaagta tgcatatttt taatccaagt ggaattaaaa gtatggaaca
    16321 aggactatca tttaatacaa taataagttt tatgacaaat acaaatcttc aacattattc
    16381 aggtgaatca ggactttcat actttagtca gatgacagtg ataatatata tgatgtttac
    16441 atcagctgca acaggatatg cggctgctat ggcatttgta agaggtctag tcggtaaaaa
    16501 gaaaacattg ggaaattttt atgtagattt aattaggata acaacaagag tacttttacc
    16561 aggagcttta attattgggc ttatattagt tacacaagga gtaccacaaa cttttgctgg
    16621 gacagaaaca gtgactacta tagaaggaaa gcttcaagat atagctagag gtcctgtggc
    16681 agctcttgaa tcaataaaac atttaggaac aaatggtggt ggattctttg gttcaaattc
    16741 atcacaccca tttgaaaatc caacaataat atcaaatata gtagaaatat tatctatgat
    16801 gatattacca ggagcttgtg ttgttgcatt tggtcacatg ataaagaata aaaaacaagg
    16861 ttgggttgtg tttggcgcaa tgtcaatcat atttttaata ggtctagtag tgtgctttaa
    16921 agcagaaagt gcaggaaatc ctattttatc acaattaggg cttaatcaaa gtatgggaag
    16981 tatggaaggt aaggaagtta gatttggtat agcacaatca tcattattca caacagtgac
    17041 tacttccttt acgacaggta cagttaataa tatgcatgat acactgactc ctttaggagg
    17101 attagtacca cttttaaata tgatgctaaa tgtagtattt ggtggtaaag gcgtaggtct
    17161 gatgaatatg ttgatgtacg ctataatagc agtattctta tgtggattaa tggtaggaag
    17221 aacaccagag tttttaacta agaaaatcga aggaaaagaa atgaagctta ttgctttact
    17281 tattatatta catccacttt taatactaat gttctctggt ctttcagtag caataccagc
    17341 agggcttgaa ggaatttcaa atcctggatt ccatggatta tcacaggtat tgtatgagtt
    17401 tgcatcttca gcagccaata atggttcagg atttgaaggt ctaggagata acactatgtt
    17461 ttggaatata acaacaggtg tagttatgtt ctttggaaga tatgtgtcta ttatagtact
    17521 actagcaata tcaagtttgt tagcatctaa aaaagctgta aatgaaagta taggaacact
    17581 tagaacggat aattttacat ttacaatagt tttagtactt gttgttttaa ttgttggtgc
    17641 tttaacattt ttcccagcct tagcgcttgg acctatttcg gagcatctag tgttgtggca
    17701 ctaaaaaatt gggagggagt aaagttttat ggaaactaaa aaaacaaagt ttattacaaa
    17761 agatattttc aaaacttcca ttatagaagc ttttaaaaaa ttaaatccta aatacatgat
    17821 gaaaaatcca gttatgtttg ttgtagaaat tggatttata gtaacattga tacttacaat
    17881 agtacctagt ttgtttggtg atgaaggcaa taacttaaga gcttataatg ggattgtaac
    17941 aataatctta tttataacag tcctttttgc aaattttgct gaagctgtag ctgaaggaag
    18001 aggtaaagct caagcagata cacttaagaa aactagaaaa gatacagtag caagggttat
    18061 agatacgtta ggaaatgaaa aaatgataag tgcaagtgag ctaaaacttg gtgatattgt
    18121 tttagtaaat gctggagaag ttattccaaa tgatggagaa gttatagagg gtatagcttc
    18181 tgtggatgag tcagcaataa ctggagaatc tgcacctgtc atgagagaat caggtggaga
    18241 tttcgcatct gttacaggtg gtactacagt tgtaagtgac tggttaaaga taagaataac
    18301 aacaaaacca ggagaatcgt tcttagataa aatgatagct cttgtagaag gtgcttcaag
    18361 acaaaaaacg ccaaatgaga ttgctttaaa tactttatta gtagggttaa cacttatatt
    18421 tatggttgtt ttaatatctc tttatccaat ggcaaactat gcaggtgtaa agattccaat
    18481 ttctactatg atagctcttt tggtatgttt aataccaact actataggtg gattgttgtc
    18541 agctattggt attgcaggta tggatagagt aactagattt aatgtaattg caatgtcagg
    18601 aaaagcagta gaagcttgtg gagacgttga tactatgatt ttggataaga caggtacgat
    18661 tacttatggg aatagacttg catcagaatt tatagcagtt ggaaatgcag attcaaaaga
    18721 tttaataaat tattctgtta tgtgttcatt aaaagatgat acaccagaag gaaaatctat
    18781 agttgattta ggtatgaaat taggttcaac aggtaagaca aaagaggcag aggaagctga
    18841 gtttgtagaa ttttctgcac aaactagaat gagtggtatt aacttagctg atggtagagc
    18901 tataagaaaa ggtgcttatg atagcataat aaaaagagta aaagaatctg gtggtacagt
    18961 gccagaagat ttagaagaaa atgtaaatcg agtagctaaa ctaggaggaa cacctttagt
    19021 agtgtgtgta gataatgaga tatatggaat tatctactta aaagatacag taaaatcagg
    19081 gcttgtagaa agatttgcta gacttcgaga gataggaata aagacaataa tgtgtacagg
    19141 ggataatccc ttgacagcag ctacaattgc aagagaagct ggagtagatg gatttattgc
    19201 agaatgtaaa ccagaagata aaatagatgc aataaaaaaa gaacaattag agggtaaaat
    19261 agttgcaatg acaggtgatg gaacaaatga tgctcctgca cttgctcagg cagatgtagg
    19321 tcttgcaatg aatagtggta caacatctgc aaaagaagca gcaaatatgg tagatttaga
    19381 ttcagaccca actaagatat tggaagttgt tgaaatagga aaacagcttt taataactcg
    19441 tggggctttg acaacattta gtatagcaaa tgatgttgca aaatattttg cgattatacc
    19501 agctatattt actcttgcaa tacctcaaat ggagatatta aatgtaatga aactttctac
    19561 gtcatttagt gcgatattat cagctttaat atttaatgct ataattatcc catgtttaat
    19621 acctcttgca atgaagggag taaaatatag acctatgaaa tcacaagcta tgttaatgag
    19681 aaatatgctt atatttggtc ttggtggagt tatagtacca tttttaggaa taaaattaat
    19741 tgatttattg attacacctt tagtaatggt tcttaattta ggttaataaa tggaggatat
    19801 aaaaatgaaa acattaaagc cagcattact tgtaagtatt gtattgttag ttgtttgtgg
    19861 acttgtatat ccacttgttt tgacaggtgt aagtcaagtt gcatttaaag ataaagccaa
    19921 tggaagtatg atagaagtaa atggtgtaaa agtaggttca gaacttattg gtcaaagctt
    19981 tacagatgcg agattcttta agggaagagt atcatcagta aactataata cttatacaaa
    20041 agaagattta gtaccagata aagatggaaa tacatcttat ggaggtgtat catcagggtc
    20101 ttttaattat ggagctacaa atccagaact tcatgataga gtacaaaaag atatagaaaa
    20161 gtttttaaag gataatccaa ctgtcaaaag agaggatata ccaacagatt tacttacagc
    20221 atcaggttca ggacttgacc ctaatataag tccagcctct gcaaaaattc agataccagc
    20281 tatagcaaaa gcgtctggaa tatcagaaag taaattacaa aaaattgtag atgataatac
    20341 ttccaaaaaa ctttttggag ttttaggtga agatagagtt aatgtattaa aagttaatgt
    20401 agaggtcgca aaaatattag gtcttatata gtattttgtg gaattttagc aacaaaatat
    20461 tacgcaagat ttaatttaaa ggttaaattt taaagagtga aaatcgataa tgattttcac
    20521 ttttttattt gaatattact aatatttgga ataaagtgat tgtaagtata aaatccaaaa
    20581 aaaggttgca ttatcaaaat gataatacta taatatattt atcgttatca atttgataat
    20641 agatttggac atataggagg aaatagtatg ttatataata acgcattaga gttgatagga
    20701 aacacacctg tagtaaggct gaataattta ggctgtacta atgggtgttc taacatatat
    20761 gtaaaattag aaaaagtaaa tccagcagga agtataaaag atagagctgt ttatgaaatg
    20821 ttagagggct tagagcaaag aggagaatta aaaaagggag atgtactagt tgaagcaact
    20881 agtggaaata ctggtattgc attatctatg ataggaaaat taaaaggata tgaagtagta
    20941 atcgtaatgc ccgaaacaat gagcgttgag agaagagatt taatgaaggc ttatggagca
    21001 aatttggtgc ttacagatgg taaagctgga atggcaggtt ccatagaaaa agcaaatgaa
    21061 cttttaaaag aaaatccaaa ctataaaagc ctaaaacaat ttgaaaataa agataatcca
    21121 aatgcacatt ataaaacaac agcagttgaa attatgaatg atgtcaaaga tttagatata
    21181 ttcgtatgtg gagttggaac aggtggtact ttaataggaa ctgcaagata tttaaaagaa
    21241 caaaatccaa atataagagt aattgcactt gaaccaaaaa aatctccagc tatatcagaa
    21301 aacaagactg gacctcataa aatacaagga ataggtgcta actttgttcc tgaaaattat
    21361 gattctagtg tagttgatga agtaatatta gtagatgatg aagatgcatt tgatacagtt
    21421 aaattacttg cagcaaaaga gggaatttta gtagggatat cttctggagc aaatatattt
    21481 ggtgctatag agatggcaaa aaagtatcca gataaaaaga tagttacagt agctccagat
    21541 ggagttgata agtatatgtc tatgggaata ttttaataat tttatttgag ggagtgaata
    21601 ctttgtttaa gaaaataaat aaagatattg aatatataat gaagaatgat ccagcagcta
    21661 ggtctaagat agaagttttt ttactttatc catcagttca tgcaatgata atgcatagga
    21721 tggctcatgc tctttataag aagaagaagc tttttacagc aagattaata tcccagatat
    21781 ccagatttat gactggcata gaaatacatc ctggtgctaa aatgggggaa ggtatattga
    21841 tagaccatgg aatgggtgtt gtaattggag agacagctga agtagggaat agggtgacaa
    21901 tatatcaagg agctacttta ggagctacag gaaaagatac tggaaagaga catccaactg
    21961 ttggtgatga tgtattaatt ggtgctggaa caaaaatact aggaccttta aatataggtt
    22021 caaattcaaa aattggtgca aattctgttg tcgttaagga tgtacctaat ggtgcaacag
    22081 ttgttggtat accagcaaaa atagtaaaaa taagaaacct agaacctgta aaaaagaata
    22141 aaaaagaagt gtcctatgag tatgatgaat tagataatgt atattatata taggatttat
    22201 ataactataa aataaacttt ataaaaatta ttttaaaagg tatttttttc aaatttgagg
    22261 acataataaa aaagaactga atgttacagt tttggttcat caatctttga taaacaagat
    22321 tttaaatttg tagcgtctag gaggatttta ttatgaaagc aaatgttaat caagatactt
    22381 gtataggttg tggattatgt ccatcaatat gtccagaagt atttgatatg aaggatgatg
    22441 ggaaatcaca tgttatagtt gatgaagtac caagtgatgc tgaagaatca gcagcagaag
    22501 ctagagaaag ctgtccagtt gatgcaatag atgtgcatta ataaaataaa tgcctataaa
    22561 aattgaattt tcaattttta taggcatttg tcttttattc agttagtatt tcaacacctg
    22621 tttctgtaac taaaaccata cattcccatt gagcagataa tttaccatct tttgtataaa
    22681 tagtccaatt attttcttca tcaacaaaaa tttcgtgagt tccttcattt accataggtt
    22741 ctattgtgaa tatcatccca ggaaccaata gcatctcagt ccctttttta gatacataac
    22801 ttacaaaagg gtcttcatga aagcttaatc caactccatg accacctatt tctctaacaa
    22861 cagagtatcc atttttcttt gcataagagt tgatagcatc acctatatct cctaaaaatc
    22921 cccatggttt ggcaacttca agaccttttt ggacacattc ctttgtaact tgaactaatt
    22981 tttttgcatt ttcattaaca ttacctatca taaacattct tgaagcatct gaatagtatc
    23041 cattaaaaat agtagaaaca tctacattta taatatctcc atcttttaag ataatgtctt
    23101 tacttggaat accatgacaa acttcattat ttactgatgt acatacactt ttaggaaatc
    23161 cattatagtc tagtggagca gggatagctc cattttgtag tgtaaagtca tgaaccaact
    23221 tatttatatc ttctgtagac attccaattt cgattttatc tgaaatataa tccaaaattt
    23281 ttgtgtttat tacagcactt ttttttattt cctcaatttg actttcattt tttataatat
    23341 catgagttgg tacaatatga cctaacttag caaatgaatc tattttatta tccatatcca
    23401 tatgacattt tttatatttt ttagtacttc cacaccaaca gctatcattt ctatttaact
    23461 tcataacttt tcatccttct tttattattt atttaaatta tgggttacat aaactatttt
    23521 aaaacataac cattataaat attataacat aaatactaag aaatccttta tagatagtga
    23581 tttattcaaa gtataaatta ttatatggtt attgttgatg aaaagaggat agttaaatgt
    23641 attattggat attagcgcac ttaatagttt agttcaagtt tttcaagaaa atcatatgtt
    23701 agaggacaat tttcctttaa agtatttttt gaatcttcat caagataata atgtacaaat
    23761 gattctgcaa aaaattcttc tataaacttg cttatatatg catgtgcaac ttgcttaggg
    23821 tcataaagct tatatctttc ctgagcaaat acttccataa attcttcaga atttgatttt
    23881 ttatttaaaa catttttatc tatagcatgt gcagtttcat gtaattctaa attttttgat
    23941 gaatgtacat ttgcatagct agggttacta taacctattt tagccactat agaattattt
    24001 ctatatatac caggtacatc tttccaagtc ttgcctgatc ttacccaaca tggaggtaat
    24061 tgatatttta aatcactaaa ttctggttca tcagttagat ttgaatttat taattttatt
    24121 tttatatcct tttctttaag tgtctgtaaa tatttaatat ttatttttgc aagtctgttt
    24181 ttcatatttt caacttcatc tttatcataa ttcaagtcat caggaagtat aagcatttgt
    24241 tcaattatat ctatactact gtcttttata ttttcagatt cttcatcaaa cttatattga
    24301 agagtattat tttcatagat agttatattt gtattatttt ctatagaata agagtgaata
    24361 tcctctaaat ctaaaatatt catttgttgt aaaatatgtt ttgtttcgcc actccatact
    24421 actaaagaaa gtgaattaaa attaattagt ggattttctt ttgcttttat atcattgctt
    24481 atatctacat caaatacata ttcaattgag tcttctatgt taagaccatc tgtattcttt
    24541 ttaatatata aatacgcttg ttttaagtct atataaatct catctaaaga ttcgtcataa
    24601 aattctgata aattattagt aaagagttct tcacttaaaa gttcattttt atcagttata
    24661 ctttcaatta aaatattaat ttcttttatc atatcgtaaa tacttatttt tctatttgct
    24721 ttttcactag atacattgca tggcgcaaga gcaatgcaat aaaaatcttt ttctttttta
    24781 taaaaggctt taagtgattt tgataaaagt gtaaagtcta cacctatctg taagttgacc
    24841 ttaagtgagt cattttgtaa taattcagta ttatttcttt tagctgtatt taaattgttt
    24901 tccataatca ttgccccctt tttattaggg tatcataatt tttttatatg tgtcaatttg
    24961 tttttttgaa aattataa
//
LOCUS       DAYAOO010000058        24685 bp    DNA     linear   BCT 12-OCT-2024
DEFINITION  TPA_asm: Clostridioides difficile isolate ST8-SSI-h139-18
            SAMN40601845-rid21577343.denovo.058, whole genome shotgun sequence.
ACCESSION   DAYAOO010000058 DAYAOO010000000
VERSION     DAYAOO010000058.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN40601845
            Sequence Read Archive: SRR28438827
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 24685)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 24685)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-MAY-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-MAY-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002157583.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002157583.1
            Genome Coverage       :: 163x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/11/2024 16:19:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 4,038
            CDSs (total)                      :: 3,963
            Genes (coding)                    :: 3,930
            CDSs (with protein)               :: 3,930
            Genes (RNA)                       :: 75
            rRNAs                             :: 6, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 60
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 33
            CDSs (without protein)            :: 33
            Pseudo Genes (ambiguous residues) :: 0 of 33
            Pseudo Genes (frameshifted)       :: 7 of 33
            Pseudo Genes (incomplete)         :: 25 of 33
            Pseudo Genes (internal stop)      :: 11 of 33
            Pseudo Genes (multiple problems)  :: 8 of 33
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..24685
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN40601845-rid21577343.denovo.058"
                     /isolate="ST8-SSI-h139-18"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Denmark"
                     /collection_date="2018"
                     /collected_by="Statens Serum Institute"
     gene            complement(167..937)
                     /locus_tag="ACGI5H_002556"
     CDS             complement(167..937)
                     /locus_tag="ACGI5H_002556"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439975.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ChbG/HpnK family deacetylase"
                     /protein_id="HFG9698256.1"
                     /translation="MKKLVVRADDIGYSEGVTLGIISSYKNGIVTSAGIMVNMPFSRQ
                     AIEMVKNDDVCFGLHVNLVIGEPCCKEHIKIKNLLDEGGKFVSSKIRRTQLLTGKEVF
                     NYEEVYEEVCAQIETYKLYMSKLPEYIDIHGIEEDVSISAMCDAAKEYGIPSCPYYLD
                     SCISMPSKYPQNDFYKLNKSFVKLFEEKYINLDKDITLMVTHPGFIDYSLIKSSSLIQ
                     ERVYEHAMLCDKEVKMWLKRNNIELVDFKDIFKSNNYI"
     gene            complement(939..2387)
                     /locus_tag="ACGI5H_002557"
     CDS             complement(939..2387)
                     /locus_tag="ACGI5H_002557"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422477.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HFG9698257.1"
                     /translation="MKRFLNKMMQQLSLLGKTMLVPIAVMPAAGILGLLFGPNMLNVP
                     AISNISNIVFSNVDYLFLLGAASAYSKSKDKTSVMVAAVVAYMIFKSNLELLNDTLNA
                     GVFGGIIVGACIAWTYNKTYKVKVPAFLSFFAGEKCVITLSPVVALILSYIFSLLWIY
                     PQAAMNQFGFWLGGAGAIGIFLFLFCNRALIPTGLHQVLNAYILFEMGEYTTSTGEVI
                     RGEIPRFMAGDPNAGFFWTGFYIIMMFSIPAISYAIYKTAQDKKKQEVKGAMTAGALT
                     SFMATVTEPIEFSFLFASPKLYIIHSFYSGLGGVVLYLLGARLGSFNGASIIDYVLSF
                     SYGDKAWLVIPVGVVFFVLYYVTFKYIIIKDNVQTPGREVEIEIGDKVSEKEKNLKLS
                     HGNFSYMAKQIIKNCGGYENIVTLNNCMTRLRLEVKDATILNDDNIKKTGAKGVIKLS
                     NTSVQIIIGTDVVKVKDEMEMQLDELRKQADA"
     gene            2757..3479
                     /locus_tag="ACGI5H_002558"
     CDS             2757..3479
                     /locus_tag="ACGI5H_002558"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861813.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HFG9698258.1"
                     /translation="MAKNKFSEIYEVLKEEILDGKYTSNMMLPTELQLIERFSCSRNT
                     VRRAISQLNTEGYVQSIKGKGVVVLENSCSNDFFLNMHNFKGVESIVEDKKVNTATSV
                     LHFSKILIDNKLSKKTGFKVGSEVYYLHRLRYIDNIPKILDINYFLCSIVKDLDVSIA
                     QGSIYKYIEECLGTKIVSSRKIFKIEKATELELKTLPLNDYNCVGVIKNSVYTDDGKL
                     FEYTESKHTPETFVFMDVTQRY"
     gene            3676..5343
                     /locus_tag="ACGI5H_002559"
     CDS             3676..5343
                     /locus_tag="ACGI5H_002559"
                     /EC_number="3.2.1.93"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898161.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003824 - catalytic activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="alpha,alpha-phosphotrehalase"
                     /protein_id="HFG9698259.1"
                     /translation="MKNWWKKATVYQIYPKSFKDSNNDGIGDINGIIEKLDYLYSLGV
                     DLLWLTPMYVSPQRDNGYDIEDYYNIDPKYGTMSDFEKLLKEAHKRDIKIMMDMVLNH
                     TSTEHKWFKESKKSKDNPYRDYYFWKDAKPDGSVPNNWISRFSGTAWKYDETTNQYYL
                     HLFEETQADLNWENEKVREECYKILEFWADKGIDGFRLDVVNLLSKTPGLPDDPITGP
                     KGDGRTHYADGPRIHEYLHNMNQKVFKPKNIVTVGEMSSTTPEECINYTRENREELSM
                     VFSFHHMKTDYKGGAKWTNEMFSLDKLKKAQSDFQYKMYEGKGWNALFYSNHDQPRAL
                     SRFGDDRFFRQESAKMLAITLFGLQGTTYIYQGEEIGMTNAYFTKIDEYDDAESKNAY
                     YHMIKSGIDEKEALLILQQKSRDNARTPMQWDNTIYKGFSNHKPWLKVNNDNISVENE
                     LNDSRSVFYTYQRLIKYRKQYDIFTEGTYRLLDENHKNLFVYEREYKNQNLLVISNFT
                     HDNVVYKLPETYLNKLNYTILETNYTRDIIENKMEIKPYESIMIYYK"
     gene            complement(5439..6758)
                     /locus_tag="ACGI5H_002560"
     CDS             complement(5439..6758)
                     /locus_tag="ACGI5H_002560"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439983.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="APC family permease"
                     /protein_id="HFG9698260.1"
                     /translation="MEKGIKLGFWSIVLLGINAIIGSGIFGLPGDAYTDIGPASILVL
                     VFCMLLAVSIALCFAEAGSWFDTDGGPYLYAKEAFGDFVGFEVGFMKWIVSMIAWATM
                     ANFFAVTLSSVWPQAAEPLTKNIIIGILVVGLGIINFMGMKQSKHLNNIMTIGKLLPI
                     VLFIAVGLFFIKGSNFTPFVIIQKGQSASSAFVAVSITLFYAFTGFESLAVAAKDMEN
                     PKKNVPKALVMVMFVVSVIYMLILGISIGVLGNGLAGSATPVADAAIKMLGPIGGYII
                     TIGTIVSVGGINIASSIFTPRSAAALVEQGLMPKSIRKTNKNGAPYIAIIVSVIGTLL
                     IAWSGSFTTLSQISVVSRFIQYIPTCLAVLILRKKYAGKDVNFRIPGGAIIPIFAVII
                     SILLLIKAGIDEPMKIVWGLGGMIIVVPIYFYMTKVYSKKYNDVEVK"
     gene            complement(6799..7545)
                     /locus_tag="ACGI5H_002561"
     CDS             complement(6799..7545)
                     /locus_tag="ACGI5H_002561"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012816377.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="gamma-glutamyl-gamma-aminobutyrate hydrolase
                     family protein"
                     /protein_id="HFG9698261.1"
                     /translation="MKKLAKKKYPIIGISGNLLIDEGGMFPGYERAYVNNDYIQSVVM
                     CKAIPYIVPIVYDDEIIKEQVSNIDALILSGGQDVNPLIWKEEPHNKLGAISPKRDSF
                     DMKLLKHALDMKKPVLGICRGEQIINVTEGGSLYQDLSLIEGAYIKHNQQHLSNVPTH
                     TVQIKEGTKLYEILGEKEVLVNSFHHLVVNKVAPGYIVSATSKDGLIEAIEKEGSEFV
                     IGIQWHPEMMTRDYDNMKKIFMAIVKEASK"
     gene            complement(7789..9798)
                     /locus_tag="ACGI5H_002562"
     CDS             complement(7789..9798)
                     /locus_tag="ACGI5H_002562"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427266.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0008134 - transcription factor binding
                     [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sigma 54-interacting transcriptional regulator"
                     /protein_id="HFG9698262.1"
                     /translation="MKTIAVVTDGLSKLECFLNKNLEMIFKDKVMIKNYYLNKITEKE
                     LIKDDIILVMIDDRVLKIKKYVEDVSKIITINRSIKQKDIYKLFSLPEGIDVLVVNDN
                     KHTVLETISNLYNIGINHLNFIPYNPNEEYRNIKIAITPGEASLVPKYIEEVIDLGHR
                     YIDSSTFIQIIAKLKLDDKEITERLIKYTDEIISLYSGINTKYKELTIKADELNSIIN
                     LSNLGMAMVSDKGNIIICNNSLGDILDIQSNIIGKNIDELENENIKKIFSLSKAHDEV
                     IKFNNKYLNVNKYNIESFGRVTGYYFCIQEITYIRKLEQNLSKKLREKGQVARYTFDD
                     IKTVSTKMERTKKLGMKIAESDYTILITGESGTGKELMAQSIHNASPRHSQPFIAINC
                     AAMPENLLESELFGYEEGAFTGALKGGKKGLFEQANNGTIFLDEIGDMPIYLQSKLLR
                     VLQENQVMRVGGENVIDIDVRVIAATNKNLLEMIKGDRFRADLYYRINVLPINIPPLR
                     ERKEDIEVMLKHFMKRKRAISQDVQDIINAYEWPGNIRELKNTAMYINIMSSEDVILI
                     NDLPHNLLNITEDFSKEISILKDRTSIEKVKLVMECLKNANNLNKNIGRNGIVNSINE
                     LGYNITEGEVRGILNMLKELDLIICESGRKGSELNRRGKNILNSI"
     gene            complement(10236..11669)
                     /locus_tag="ACGI5H_002563"
     CDS             complement(10236..11669)
                     /locus_tag="ACGI5H_002563"
                     /EC_number="3.2.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861817.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016798 - hydrolase activity, acting on
                     glycosyl bonds [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
                     /protein_id="HFG9698263.1"
                     /translation="MALRKDFLWGGATAANQCEGAWNLDGKGPSCSDMCTGGSQKVSK
                     RITRVIEKGTFYPSHEAIDFYHRYKEDIALFAEMGFKVFRFSIAWTRIFPTGMEKEPN
                     EAGLKFYENVIDECLKYNIEPLITISHYEIPFAITEKYNGWVSRDVIDLYMNYCETIF
                     KRYKGKVKYWLTFNEINSATMPMGGYLSQGILNEGTTDFINQVDIPQLRFQGLHHQFV
                     ASAKAVKLAHEIDSNYQVGCMQIFATMYPYTCNPDDAVKTQRDSRVMNYFCGDVQVRG
                     EYPTYMNRYFGENNIEIKMEKGDLEILKEGCVDFYTFSYYMSTCVSSDSKEDNTSGNI
                     LGGVKNPYLKSSEWGWQIDPEGLRYALNEIYDRYRIPMMVVENGLGAYDKKESNGVIN
                     DDYRIEYLKAHIEQMKEAVEDGVDLFGYTPWGCIDLVSASTGEMAKRYGFIYVDKYDD
                     GSGDLSRIKKKSFDWYKQVIESNGERL"
     gene            complement(11756..13672)
                     /locus_tag="ACGI5H_002564"
     CDS             complement(11756..13672)
                     /locus_tag="ACGI5H_002564"
                     /EC_number="2.7.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898181.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_function: GO:0015573 - beta-glucoside transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA];
                     GO_process: GO:0015759 - beta-glucoside transport
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="beta-glucoside-specific PTS transporter subunit
                     IIABC"
                     /protein_id="HFG9698264.1"
                     /translation="MRKYEQLSKEIIANVGGKDNISSLSHCITRLRFKLKDESIANDD
                     VLKKMDGIVTVMKSAGQYQVVIGNHVPDVYEVVCDLAGLGGDTIDNSDSDAPKGLLNK
                     FIDIISGVFQPILGVLCAAGMIKGFNAVFTALGLYGETDGAYIMLNAIGDAMFQYMPI
                     ILGYTAAKKFKLKPFIGMLIGAVLCYSGIQLDTLASTGQPLYNLFTGTIFESPVYITF
                     LGLPVIAMNYTSTVVPVILIVLLAAKLEKVFAKIIPDVVKNFFVPMAVLLVSLPLGFM
                     VIGPIATYASNIVGNGFLALFNFSPILCGALTGLLWQVLVIFGLHWGLVPIAMSNLMT
                     MGFDTILVGAFVPSFAQTAVVAAMYFKLKDKKIKELCIPAVISGICGVTEPAIYGITL
                     PRKTPFIYSCVGGGVAGAVMGIMNVKSYVMGGLGIFGIPNYINPTTGDMKGVYATIIA
                     IIVAIVVGFVLTLFFWKDDAIVEISKDDNGQGVIEKNKREVVYSPIKGEVKALEQIQD
                     AAFSTGILGKGVAITPKEGKVVAPFDGTVMTLFPTKHAIGIISDNGCELLIHIGLNTI
                     QLEGKYFKSFVNQGDKIKKGQILITFDIESISKEGYCLETPVVVTNYSDYVDILENTQ
                     KHVNNSQELITVLA"
     gene            complement(13746..14606)
                     /gene="licT"
                     /locus_tag="ACGI5H_002565"
     CDS             complement(13746..14606)
                     /gene="licT"
                     /locus_tag="ACGI5H_002565"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439998.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="BglG family transcription antiterminator LicT"
                     /protein_id="HFG9698265.1"
                     /translation="MIIEKILNNNVIITTDENHKEIVVMGRGLAYKKRTGEHISKDKI
                     DKIFKLSDPNISDKFKELIADIPIRYMELSDEIILYAKEKLGKRLNDSIYISLTDHMY
                     TAIERAREGVSVKNVLLWDIKRFYKSEFKIGLEALDYIEKKFEIRLSEDEAGFIALHI
                     VNAQMDQSIKTIYEITQIIQEISNMVKYHYRIVFDEDSVYYHRFITHLKYFAERIVSN
                     NLHENNEDDLLNVIKVKYKNAYKFIEKLDEFIHKKYNYDLTDEEKLYLTIHVERVVSK
                     SIKSDINPNN"
     gene            complement(14957..16144)
                     /locus_tag="ACGI5H_002566"
     CDS             complement(14957..16144)
                     /locus_tag="ACGI5H_002566"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439999.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M20 family metallopeptidase"
                     /protein_id="HFG9698266.1"
                     /translation="MIESIKKRAYEIENELGKEIEEVCNFIFNNPELGEEEYISSKYL
                     VEKMKEYGFDTVYPYCNMETAFRAELGDNDGPTIAFLAEYDALPGYGENKEPAHACGH
                     NWIAASTLGACIVLSKLKENFKGKIVLIGTPAEETTGGKCDLVKAGAFDDVDVSYQMH
                     IEAFNNINCKALAIDSLEFSFEGVSAHAASHPHMGVNALDAVQLTFAGINALRQHVKS
                     DVRIHGIVSNGGEAPNIVPEKAACKFFVRAAERSYLDEVTKKVINCAKGAELMTGAKL
                     SYRYFENSFDNIINNKVLQKITKNNLIEAGITDILEGKDGPVGSTDIGNVSQVCPTMY
                     TEIALDISPMVYVHEKEFLNYANSEEAYDKLHKAVKAMVGCALEIYLEDGLLDEIKKN
                     HLN"
     gene            complement(16158..17549)
                     /locus_tag="ACGI5H_002567"
     CDS             complement(16158..17549)
                     /locus_tag="ACGI5H_002567"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422454.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YfcC family protein"
                     /protein_id="HFG9698267.1"
                     /translation="MSSLKKKKFTMPQTLTIIFLLIVLMAILTWIVPSGNFERVDIDG
                     RSVVVAGTYEKAPSNPQGITDVFTAPINGFIDAAEVVGFVLIVGGAFGIVNKTGAIEA
                     VIAHTVNKMKKFQFLIIPISMILFGLGGTTFGMSEETLPFYMIFIPLMTSMGYDSLTA
                     VATVFIGATAGFGAATTNPFSVGIAQALSQIVPGSGIEFRVVMFIIYMAISIGFVMMY
                     ANKVKKDPKKSLVHDISLNQELMVNSDTNIKEFTKREAMVIAIFTIGMAIMIYGVLRL
                     EWYITEIAMIFTAIGIISGIASGLKQDEIVNSFISGAGDLITAGLCIAFARGIVIIAE
                     NGFIIDTILNSAANLLNGLPKTIFINLTFLIEGLIAFLIPSASGLASLTIPVLAPLGD
                     LVDVSRQMIVTAYQFGIGVTNLITPTSGVLMGALAVANIPWSKWVRFVIPLMVVLTIL
                     VMAFLTIGLYLGF"
     regulatory      complement(17693..17872)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00168"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="Lysine riboswitch is most abundant in Firmicutes
                     and Gammaproteobacteria where they are found upstream of a
                     number of genes involved in lysine biosynthesis, transport
                     and catabolism; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="lysine"
                     /db_xref="RFAM:RF00168"
     gene            complement(18144..19796)
                     /locus_tag="ACGI5H_002568"
     CDS             complement(18144..19796)
                     /locus_tag="ACGI5H_002568"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012816378.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HFG9698268.1"
                     /translation="MKDKLQVLSGAMMIPVILLVVAGVFIGLGSAFANMENVSALGLS
                     GLIKEGSFINVFFKVINDLGFMVMRYLPIFFVTGIAFGLSKKEKGWGALGGIVLFIGM
                     HTVISTLLAANGINSDTVTAEAFMASGLGEAEAYSRSSLYGSFLGIFSYDCSIFGAII
                     AGFVASAVHNKFVDIELPSALSFFSGPRFSMIMMFIASIVLGTAMYFIWPPVGLALSK
                     LGNWIGSSGLLGTFTFGAMDKALLPFGIHHLIAFPIEYTRVGGTMEVGGAIYEGVNNI
                     RLAQMGDPDTLSYITRNFTTGRLLIHFAILPAAALAMYKLADNANKKKAISILIPAIV
                     TAMLVGVTEPIEYTFLFVAPLLYFVAYVPLAGLTYVFTEMFNVSIMGESFRNMFPNLL
                     QPQKVDALPLLFLIPIFFIVTYIIFTWAIKKFDIKTPGRSSEEVKLYSKKEYRERQSV
                     DAGKTAYNNAVEEEVDDKDTKLVHSIIEGLGGSNNIKNVTNCATRLRVELNSIDGFYE
                     DGFWVNELGASGVVKKKNSVQVIFGPRVITIASKLKAVLGVD"
     gene            complement(19816..21219)
                     /locus_tag="ACGI5H_002569"
     CDS             complement(19816..21219)
                     /locus_tag="ACGI5H_002569"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891439.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M20 family metallopeptidase"
                     /protein_id="HFG9698269.1"
                     /translation="MIVNKELIIDYLKSNQENIINDIRSLVEIPSIRDESTTDINQPF
                     GIEIRNAFDKLIQIAKDKDFVVKDFDGYAIHIEYGEGEEVVGVLNHIDVVPIYNKELW
                     KSKPFKVCQKDNYLYGRGVNDNKGPLIGILYALLFLRELNEKPKRKIRLIVGGAEETT
                     WECMEHYFSVNEQPKFAFSPDGNFPIVNGEKGILYFNLRKKIDKDKFRNHNLVDIKSN
                     KEDGFVCDKIEAVFKTNDKKDLVESLAYYTEIEELDEGKVLVRYTGERALSRNPHRSY
                     NCAFSLAKDLEKIKKLNDKGVIIRDILNSYFTDDNHGKKLGMYKEDVDMGVSTICIMS
                     IFLEKNELNMKIDFRYPKGISWEFITNRINEIGKKENLIVDIYKDLKLLYVKPDSELI
                     NKLSNAYKQGFGKEAELFTKGAASYARVLKNGVAFGPTIEGDNPNSHQANENISIDTL
                     YKAIEVYIYALYSLAFQ"
     gene            complement(21483..21974)
                     /locus_tag="ACGI5H_002570"
     CDS             complement(21483..21974)
                     /locus_tag="ACGI5H_002570"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728636.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucose transporter subunit IIA"
                     /protein_id="HFG9698270.1"
                     /translation="MFNIFKKKENKIEKIYSPFKGNLVNLEDVPDAVFAQKMMGDGVA
                     IIPSEGKLYSPVDGEIVNVFDTKHAIMIKSNDNTNILIHVGLETMSLEGKPFDVKVKA
                     GDKVKAKDLIMEVDLDFITSNDLNIITPVVIMDDADSVKRTVKDRIEPGNVDINSIIM
                     EVE"
     gene            complement(22000..22812)
                     /locus_tag="ACGI5H_002571"
     CDS             complement(22000..22812)
                     /locus_tag="ACGI5H_002571"
                     /EC_number="3.1.3.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003440004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HFG9698271.1"
                     /translation="MRYKLICTDMDGTLMGKGFEVSEENIKALKEAMEKGIKVALVTG
                     RPYNAMKYFTSVLGDDIYIISTNGTYFKLLGYEYKKVLSKEALKKIYTIGEKYNLNKH
                     FKGCKIVISNNEIGEEHPYRLINSKNKEEDRIEIIENASCETLLEKADNEILKCILFS
                     ENVDSLREAKEEFKKQEDLEVVSSGKINFEVMSKGTSKGIAVKKFCDILGIDSKEVIC
                     IGDNENDISMIKFAGLGIAMGNATDEVKSMADFVTDTNVNDGVAKALRKILS"
     gene            complement(22825..23778)
                     /locus_tag="ACGI5H_002572"
                     /pseudo
     CDS             complement(22825..23778)
                     /locus_tag="ACGI5H_002572"
                     /inference="COORDINATES: protein motif:HMM:NF012678.4"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="iron-containing alcohol dehydrogenase"
     gene            complement(23902..>24685)
                     /locus_tag="ACGI5H_002573"
     CDS             complement(23902..>24685)
                     /locus_tag="ACGI5H_002573"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888399.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="RNA-guided endonuclease TnpB family protein"
                     /protein_id="HFG9698272.1"
                     /translation="KTNFTNGNIMYCGQYIKLPKLGMVKIRDKQVPQGRILNATISKE
                     PSGRYYVSLCCTDVDIEAFENTNNHIGLDLGIKEFCISSCGEFIENPKYLKKSLNKLA
                     KLQRELSRKTIGSLNRNKARLKVARLQEHIANQRNDFLQKLSTKLIKENDIICIEDLQ
                     VKNMIKNRKLSRSISDVSWSEFIRQLEYKANWHGRQIVKVGKFFASSQICNKCGYKNE
                     EVKDLNIREWICPSCNETHDRDINASINILKEGLRLITIQNK"
BASE COUNT         7957 a         4541 c         2705 g         9482 t
ORIGIN      
        1 attaatgcat actactcttt ttattataca taaaaaatgt gtacttccta tattgataga
       61 gatgattcaa gtttttattt tgatacatct ctatcaatat ttttttagaa aatacacatt
      121 tttttcaaat acttattttt aattaaaact ttaggtaatc tattctttat atataattat
      181 tagacttgaa aatatcttta aaatcaacca attcaatatt atttcttttt aaccacattt
      241 taacttcctt atcacatagc attgcatgtt catatactct ctcttgaata agagaagatg
      301 attttataag actataatct ataaatcctg gatgagtaac catcaatgtt atatctttat
      361 ctaaatttat atatttttct tcaaataatt taacaaaaga tttatttaac ttgtaaaaat
      421 cattctgagg atatttactt ggcatgctaa tacatgaatc caaataatag ggacaacttg
      481 gtataccgta ttcttttgca gcatcacaca ttgctgatat tgatacatct tcttctatac
      541 catgtatatc aatatactca ggcaatttac tcatatacaa cttgtaagtt tcaatttgag
      601 cacaaacttc ttcatatact tcttcataat taaaaacctc tttacctgtc agtagttgcg
      661 ttcttcttat tttgctagaa acaaattttc caccttcatc taacaaattc tttatcttaa
      721 tatgttcttt gcaacaaggt tctcctatta ctaaattaac atgtaaacca aaacatacat
      781 catcattttt taccatttct atagcttgtc ttgaaaaagg catattcacc atgattccag
      841 cacttgtaac aataccgttc ttataagaag atattatccc tagtgtaaca ccttctgaat
      901 atcctatatc atctgcccta actactaatt tcttcatttt atgcatctgc ctgctttctc
      961 aactcatcaa gttgcatttc catctcatcc tttactttaa caacatccgt tcctatgatg
     1021 atttgaactg atgtattact caatttaatt acccctttgg ctcctgtttt tttaatatta
     1081 tcatcattca aaatagtggc atccttcact tctaaacgta atctcgtcat acaattatta
     1141 agagtcacta tattttcata accaccacaa tttttaatta tctgtttagc catatatgaa
     1201 aaattaccat gagaaagttt taaattcttt tctttttcac taactttatc acctatctct
     1261 atctcaactt cacgtcctgg tgtttgcaca ttatctttta ttattatata tttaaatgtt
     1321 acataatata atacaaagaa tacaactcct acaggtataa ctaaccacgc tttatctcca
     1381 taactaaaac ttaagacata gtcaattata cttgctccat taaatgaacc caagcgagca
     1441 cccaataaat atagtacaac tccacctaga ccagaataaa aagaatgaat tatatataac
     1501 tttggagatg caaataaaaa cgaaaattct attggttcag ttactgttgc cataaaagaa
     1561 gtcaatgctc cagcggtcat tgcacctttt acttcttgct tctttttatc ttgtgctgtt
     1621 ttatatatag cataagaaat agcaggtatt gaaaacatca taattatgta aaatcctgtc
     1681 cagaagaatc ctgcatttgg gtctcctgcc ataaatctag gaatttctcc tcttataact
     1741 tctcctgttg atgttgtata ttcacccatt tcaaataata tgtaagcatt taaaacttga
     1801 tgtaacccag ttggtattag tgcacggtta cagaataaaa acaagaatat tcctattgca
     1861 ccagctcctc ccaaccaaaa accaaattga ttcattgcag cttgtggata tatccataat
     1921 aaactaaata tatatgataa aattaaagca accactggtg atagtgtaat tacacatttt
     1981 tctcctgcaa agaagcttaa aaatgctgga actttaactt tatatgtttt attgtaagtc
     2041 catgctatac aagctccaac aattatccca ccaaatacac ctgcatttaa tgtatcattc
     2101 aataactcta aatttgactt aaatatcata tatgcaacta cggctgcaac cattacactt
     2161 gtcttgtctt tagactttga gtaggcacta gctgctccta ataaaaataa gtagtccaca
     2221 tttgaaaata ctatattaga tatattagat atagctggca cattgagcat atttggacca
     2281 aataataatc ctaatatacc tgctgctggc attacagcta ttggcaccag catagtcttt
     2341 cctaaaagtg acagttgttg catcattttg tttaagaatc tcttcatatc caatcccctt
     2401 tctatttcgg tttaattttt tgtgaaaacg atttattcac attttatatt ttaaatatta
     2461 tatttgttta aacaaattgt caatattttt tattcatttt atttttatca tttagtttaa
     2521 catataaatc cttttaagtg tattgctata tctagtctat ttttttaatt catttttttt
     2581 attttaaaaa tatgtttaac catgtatttg aaacaaccca caaaataatt ctattttgtc
     2641 ctttttatgg ttgatatgat tctattttca ctatacatgt ctaaacacat ttgatataat
     2701 ttgttcatat cagttcaata atattactaa agacctttaa ggagggatag gggtatatgg
     2761 ctaaaaataa attttcagag atatatgaag tattgaaaga ggaaatactt gatggtaaat
     2821 atacaagtaa tatgatgctg cctactgaac ttcaacttat tgaaaggttt tcatgtagca
     2881 gaaacactgt acgtagagca atttctcaat taaacacaga aggatatgtt caaagtataa
     2941 aaggcaaggg tgttgtagtg ttagaaaata gttgttctaa tgattttttt ctaaatatgc
     3001 acaatttcaa aggtgtagaa tcgattgtag aagataaaaa ggttaatact gctactagtg
     3061 ttctccactt cagcaaaatc ttaattgata ataagttatc taaaaagaca ggttttaaag
     3121 ttggtagtga agtatattac cttcacagac taagatatat tgataacata cctaaaattc
     3181 tcgacattaa ctattttcta tgtagtatag ttaaagacct tgatgtttct atagcacaag
     3241 gctctattta taaatatata gaagagtgtc taggtacaaa aattgtttca tcaagaaaga
     3301 tatttaaaat tgaaaaagct acagaacttg agttaaaaac gctacctcta aatgattata
     3361 attgtgttgg tgttattaaa aatagtgtat atactgatga tggaaagctt tttgaatata
     3421 ctgaatcaaa gcatacacct gaaacatttg tattcatgga tgttactcaa agatattaaa
     3481 aaaattatgt ttaattaaac ataatttttt tacgtttaga cactttatcc catactaacc
     3541 tcactattct atatacaatt atatgtttat acaaataatt atttattgta tattttagct
     3601 ttaatattag tttaacgctt gacaatttgt ttaaacatat tataattaac ttataaatta
     3661 caggaggtat caagtatgaa aaattggtgg aaaaaagcaa ctgtctatca aatatatcca
     3721 aaaagtttca aagatagcaa caatgatggt ataggtgata taaatggtat tatagaaaaa
     3781 ttagattatc tgtattcttt aggtgttgat ttattatggt tgactcctat gtacgtttct
     3841 cctcaaagag ataatggata tgatatagaa gattattata atatagaccc aaaatatggg
     3901 acaatgagtg actttgaaaa actcttaaaa gaagctcata aaagagacat aaaaataatg
     3961 atggatatgg tcctaaacca tacatctact gaacataaat ggtttaaaga atctaaaaaa
     4021 agcaaagaca atccatatcg tgattattat ttctggaaag atgctaaacc tgatggttct
     4081 gttcctaata actggatatc cagatttagt ggaactgctt ggaaatatga tgaaaccact
     4141 aaccaatatt atttacattt atttgaagaa actcaagctg atttaaattg ggaaaatgaa
     4201 aaggttcgtg aagaatgtta caaaatacta gaattttggg ctgataaagg tattgatggt
     4261 tttcgtttag atgtagtcaa cctactctcc aaaacacctg gattacctga tgaccctata
     4321 acaggaccaa aaggagatgg aagaactcac tacgctgatg gtcctcgtat acacgaatat
     4381 ttacataata tgaatcaaaa agttttcaaa cctaaaaata tagttactgt aggtgaaatg
     4441 tcatctacta cacctgaaga gtgtatcaac tatactagag aaaatcgaga agaactatct
     4501 atggttttta gcttccatca tatgaaaaca gattataaag gaggcgcaaa atggactaat
     4561 gaaatgttct ctctggataa attaaaaaaa gcacaatctg actttcaata taaaatgtat
     4621 gaaggaaaag gatggaatgc tctattttac tctaatcacg accaacctag agctttatct
     4681 agatttggag atgatagatt ttttcgtcaa gaaagtgcta agatgttagc cataacatta
     4741 tttggtctac agggtactac atacatatat caaggtgaag aaataggtat gacaaatgcc
     4801 tactttacta aaatagatga atatgatgat gctgaaagta agaatgcata ctatcatatg
     4861 attaaatctg gtattgatga aaaggaggca ttgcttatac ttcaacaaaa atccagagat
     4921 aatgcccgta ctcctatgca atgggataat actatttata aggggttttc taatcataaa
     4981 ccgtggttaa aagttaataa tgacaatatt agtgtagaaa atgagcttaa tgattctcgt
     5041 tcagtatttt atacttatca aagattaatc aaatatcgta aacaatatga tatttttaca
     5101 gaaggtactt atagattgtt agatgaaaat cataaaaatc tatttgttta tgaaagagag
     5161 tataaaaacc aaaatcttct tgttataagt aattttactc atgataatgt agtatataaa
     5221 ttacctgaaa cttatttgaa taaattaaac tacacaatac ttgaaaccaa ttacactaga
     5281 gatataattg aaaataaaat ggaaataaaa ccttacgaaa gtataatgat atattataaa
     5341 taaagttatt tatgtaaaaa tcggtataac accctggtgt tataccaatt ttactaaatt
     5401 caaagtaata tttatagaat atctatagat tacaataatt atttgacttc tacatcatta
     5461 tatttctttg aatatacttt agtcatatag aaatatatag gaactacaat tatcatccca
     5521 cctaatcccc aaactatctt cataggttca tcaatacctg cttttatcag taataatata
     5581 cttataataa ctgcaaatat tggtataatt gctcctccag gtattctaaa atttacatct
     5641 ttaccagcat acttctttct caatattagt acagctaaac atgtaggaat atattgaata
     5701 aatctagata caacacttat ttgagataat gttgtgaatg aacccgacca tgctattagt
     5761 aaagttccta tgacagatac tataattgct atataaggag ctccattttt attagttttt
     5821 cttatagact taggcattaa tccttgttca accaaagcag cagcagacct tggtgtaaat
     5881 atggatgatg caatatttat acctccaaca gatactatag ttcctattgt aattatatac
     5941 ccacctatag gacctaacat cttaatggca gcatctgcaa caggagtagc tgaccctgct
     6001 aagccattac ccaacacccc tatacttatt cccagtataa gcatatatat tactgatact
     6061 acaaacatta ccattaccaa tgctttaggt acatttttct tagggttctc catatctttt
     6121 gctgcaacag ctaaagattc aaatcctgta aaagcataaa ataaagttat agatactgct
     6181 acaaaagctg atgacgcact ttgacctttt tgtattatta caaatggggt aaaattagaa
     6241 ccctttataa agaataatcc tacagctata aataaaacta ttggtaataa ttttcctata
     6301 gtcatgatat tatttaagtg cttagattgt ttcatcccca taaaatttat aatcccaagt
     6361 cctacaacta atataccaat tattatattt ttagtaagtg gttctgctgc ttgtggccat
     6421 acagatgata gtgttacagc aaagaaattt gccatagtag cccaagcaat catactaact
     6481 atccacttca taaatccaac ttcaaatcca acaaaatctc caaatgcctc ttttgcataa
     6541 agatagggcc ctccatcagt atcaaaccaa ctacctgctt cagcaaaaca taaagcaata
     6601 gaaacagcta aaagcataca aaaaactaat actaatatac ttgctggacc tatatctgta
     6661 taagcatcac caggtaaccc gaatatacct gaccctatta ttgcattgat tcctaatagt
     6721 acaatactcc aaaaacctaa cttaatgcct ttttccattg ttattccccc caaagccaac
     6781 ttaatatatt tgtatttttt atttagatgc ttctttaact attgccataa atattttttt
     6841 catattatca taatccctag tcatcatttc tggatgccat tgtatcccta ttacaaactc
     6901 acttccttcc ttttctatag cttcaattaa accgtcttta gatgtagctg aaacaatata
     6961 tcccggtgct actttgttga caactaagtg atgaaaacta ttaactaaaa cttctttttc
     7021 tcctaatatt tcatataatt ttgtcccctc ctttatctgt actgtatgtg taggtacatt
     7081 agatagatgt tgctgattgt gtttaatata agcaccttca attaaagata aatcttgata
     7141 caaactacct ccttcagtta catttataat ttgttctcct ctacatatac ctaaaactgg
     7201 ttttttcata tctaaagcat gttttaataa tttcatatca aaactatctc tctttggtga
     7261 tattgccccc aacttattat gaggttcttc tttccatatg agtggattta catcttgtcc
     7321 cccagatagt ataagcgcat ctatattaga tacctgctcc tttataatct catcatcata
     7381 tacaatcggt acaatatatg gtatagcttt acacataact actgattgta tataatcatt
     7441 atttacataa gccctttcat agccaggaaa cattcctcct tcatcaatta gtaaattacc
     7501 tgatattcct attattggat atttcttttt agccaatttc ttcacccctt aacttatttg
     7561 tgaacaataa aaaatgctac ttctcttaaa gagcaagtag cataccaaga ttttatttat
     7621 ttgaacatta taatttattt tagaaatact ttttttgaat acgagtaata taaataactt
     7681 tatttactta tattttattt taatcctgtt tagtttgact tttttaaatt gttttaagta
     7741 caactaatag gtaaaatagg catttagatt ttccttttta tcaacctatt aaatactgtt
     7801 taatatattt tttccccttc tatttaattc acttcccttt ctaccagatt cacatattat
     7861 caaatccagc tcttttaaca tattaagtat tccccttacc tcaccttctg ttatattgta
     7921 gcctaattca tttattgaat taacaatacc atttctacct atatttttat taagattatt
     7981 ggcatttttt aaacactcca ttactaactt tactttctct atagatgttc tatcctttaa
     8041 tatacttatt tctttactaa aatcttcagt tatatttaat aagttatgag gtaaatcatt
     8101 tattaaaata acatcctcag aactcataat gttaatatac atagcagtat tttttaattc
     8161 tcttatatta cctggccatt catatgcatt aataatgtct tgaacatctt gactaattgc
     8221 tctcttcctt ttcataaaat gctttaacat aacttctata tcttcttttc gctctcttaa
     8281 aggtggtata tttatgggca atacatttat cctatagtat aaatctgctc taaatctatc
     8341 tccttttatc atttctaata aatttttatt tgtagccgca attactctaa catctatatc
     8401 tattacattt tctcctccaa ccctcattac ttgattctct tgtaatactc taagtaattt
     8461 gctttgtaag tatataggca tgtctcctat ttcatccaaa aatatagttc cattgttagc
     8521 ctgttcaaat aatccttttt tacctccttt taaagctcct gtaaaagcac cttcttcata
     8581 tccaaaaagt tcactttcaa gtaaattttc tggcatagct gcacagttta tcgctataaa
     8641 tggctgacta tgtcttggtg atgcattatg aatagactga gccatgagtt cttttcccgt
     8701 tccactttct cccgttataa gaattgtata atcagattca gctattttca tacctaattt
     8761 cttagttctt tccatcttcg ttgaaactgt ttttatatca tcaaaagtat atctagcaac
     8821 ttgtcccttt tctctaagct tctttgatag gttttgctcc aattttctta tgtaagttat
     8881 ttcttgaata caaaaataat atccagtaac ccttccaaaa ctctctatat tatacttatt
     8941 tacgtttaag tacttattat taaattttat aacttcatca tgtgccttac tcaaactaaa
     9001 aatcttttta atattctcat tctctaattc atctatattt ttccctataa tattactttg
     9061 aatatctagt atatccccta aactattatt gcaaataatt atgtttccct tatctgatac
     9121 cattgccata cctaagtttg ataaatttat tatagaattt aattcatctg cttttatagt
     9181 aagttcttta tatttagtat ttattcctga atataaacta attatttcat ctgtatactt
     9241 aattagcctt tcagtaattt ctttatcatc cagtttgagt tttgctatta tttgaataaa
     9301 cgttgaacta tcaatatacc tatggcctaa atcaataact tcttctatat attttggaac
     9361 taaacttgcc tctcctggcg ttatagctat cttaatattt ctatattctt cattgggatt
     9421 gtatggtata aaattcagat gatttattcc tatattgtat aaattagata ttgtttccaa
     9481 tacagtatgc ttattatcgt ttactactaa tacatctatt ccttctggca atgaaaataa
     9541 cttatatata tccttttgct ttatgctcct atttatagtt attatctttg agacatcttc
     9601 tacatatttt tttattttta atactctatc atctatcatt accaatatta tgtcatcttt
     9661 tattaattcc ttctctgtta ttttatttaa ataataattt tttatcatta ctttatcttt
     9721 aaatatcatt tctagatttt tatttaagaa acattctaat ttagacaacc catcagttac
     9781 tactgctatt gttttcattt gattactcct tttaaaatat actctactct tttataatat
     9841 acatctgatt ttcactttaa cagcacaaaa aattgtacat ttagtatact aacatattcc
     9901 tttattagtt ttatgtccct aaatatcata gttgcaatat ctatcatatt tcttaaactt
     9961 ctataaagca aaaattgtgc caaattaata attttcttaa ttttattcta aagttcctca
    10021 atagtattta cagacttagc acttatagct tataagtctt tatattatta atctattttt
    10081 ataggttaat tgtacaaatc atatatcact tttacccatt aaatgcatta taaaaaagat
    10141 ggaataacga ttcgtcactc cacctttttt gtaataaaaa attgtatata taaacactat
    10201 ttactactct tctaagtaca aacattatct acatactata acctttcacc attagattct
    10261 attacttgtt tataccagtc aaaactcttt ttcttaatcc tagacaagtc tccacttcca
    10321 tcatcatact tatccacgta tataaaccca tatctcttgg ccatctcacc agtagatgca
    10381 cttactaaat ctatacatcc ccacggagta tatccaaata aatcaacacc atcttctaca
    10441 gcttccttca tttgctctat atgtgctttt aaatactcta tacgatagtc atcatttatc
    10501 actccattag attctttttt atcataagct cctaaaccat tttcaactac catcataggt
    10561 attctatatc tatcataaat ttcatttagt gcatatctaa gcccttcagg gtctatttgc
    10621 catccccatt cactagactt aagatatgga tttttcactc cacctaatat gttgccactt
    10681 gtattatctt ctttagaatc actacttaca catgtagaca tataataact aaatgtataa
    10741 aaatctacac aaccttcttt taaaatttct aaatctcctt tttccatttt tatttcaata
    10801 ttattttctc caaaatatct attcatataa gttggatatt cgccacgcac ttgtacatct
    10861 ccacagaaat aattcattac tctactatct ctttgagttt taactgcatc atctggatta
    10921 caagtataag gatacattgt tgcaaatatt tgcatacatc caacttgata atttgaatct
    10981 atttcatgag ctaacttaac agccttagca cttgctacaa attgatgatg taacccttga
    11041 aaacgaagtt gaggtatatc tacttggttt ataaaatctg tagtcccttc atttaatatt
    11101 ccttgtgata agtagcctcc cataggcatt gtagctgaat ttatttcatt aaatgtcagc
    11161 caatatttta cttttccttt atatctttta aatattgttt cacagtaatt catatacaag
    11221 tctattacat ctcttgaaac ccatccattg tatttctctg ttattgcaaa tggtatttca
    11281 tagtgagata ttgttattaa tggttctata ttatatttta aacattcatc tatcacattt
    11341 tcataaaatt taagtcctgc ttcatttggt tctttctcca ttccagttgg aaatattcta
    11401 gtccatgcta ttgaaaatct aaatacctta aatcccattt ctgcaaataa agctatatct
    11461 tctttgtatc tgtgataaaa atctattgct tcatgacttg gataaaatgt tcctttttct
    11521 ataactctcg ttattctttt acttactttt tgagaacctc cagtacacat atctgaacaa
    11581 gaaggacctt tcccatctaa attccatgct ccttcacatt gatttgctgc tgttgctcca
    11641 ccccataaaa aatcttttct aagtgccata attctacctc caataattta tttatagtaa
    11701 ctttatttta aaataaaaat acatatatat aattcttaat taatagaact ctcttttacg
    11761 ctaaaacagt tatcaattcc tgactattat ttacatgctt ttgtgtattt tctaaaatat
    11821 ccacataatc agaataatta gtaacaacta ctggtgtttc taagcaatat ccttcttttg
    11881 aaatactttc tatgtcaaaa gttattaata tctgaccttt tttaatctta tccccttgat
    11941 taacaaaaga tttgaaatat ttaccttcca actgaatagt atttaaccct atatgtatca
    12001 atagttcaca accattatca gatataattc ctattgcatg ttttgttgga aataaagtca
    12061 ttacagtccc atcaaatggt gccactactt ttccttcttt aggtgttatt gctacacctt
    12121 ttcccaatat acctgttgaa aacgctgcat cttgtatctg ctccaaagcc tttacttcac
    12181 cttttattgg gctatatact acttctcttt tgtttttttc tataacgcct tgcccattat
    12241 catctttaga aatttctact atagcatcat ctttccaaaa aaataatgtt aaaacaaatc
    12301 ctactacaat agctactatt attgctatta tagttgcata aacacctttc atatctccag
    12361 ttgttggatt tatataatta ggtataccaa atattccaag tccacccatt acataacttt
    12421 ttacattcat tatccccatt acagctcctg ccacaccacc acctacacag ctatatatga
    12481 atggtgtttt tcttggtaaa gttattccat atattgcagg ctctgttaca ccacatatcc
    12541 ctgaaataac tgcaggtata cacagctctt ttatcttctt atcttttaat ttaaagtaca
    12601 ttgctgctac tactgctgtt tgtgcaaaag atggtacaaa tgctcccact aatattgtgt
    12661 caaaccccat agtcataagg tttgacatag ctattggtac taatccccaa tgtagaccaa
    12721 atattacaag cacttgccac aataaaccag ttaatgcacc acataaaatt ggtgaaaagt
    12781 taaataaagc taaaaatcca tttccaacta tattagaagc ataggtagct ataggcccta
    12841 taaccataaa tcccaatggt aaagaaacta ataaaactgc cattggtaca aagaaattct
    12901 ttactacatc tggtattatt ttagcaaaca ctttctccaa cttagctgct aataatacta
    12961 ttaaaattac tggtactact gttgaagtgt agttcattgc tattactggt aatcctaaga
    13021 aagttatata tactggtgat tcaaatattg ttccagtaaa tagattgtat aaaggttgac
    13081 ctgtagatgc tagagtatct aattgaatac ctgaatagca taaaactgca cctataagca
    13141 ttccaataaa tggttttaat ttgaatttct tagcagctgt atatccaaga attattggca
    13201 tatactggaa cattgcatct ccaattgcat ttaacataat atatgcacca tcagtttctc
    13261 catacaaacc caatgctgta aatactgcat taaatccttt tatcatacca gcagcacaca
    13321 gaactcctaa tattggttga aaaactcctg atattatgtc tataaactta ttaagtaatc
    13381 cttttggcgc atctgagtct gaattatcta ttgtatctcc tcctaatcca gccaaatcgc
    13441 acacaacttc ataaacatct ggaacatgat taccaataac tacttggtat tgacctgcac
    13501 ttttcattac agtaactata ccatccattt tttttagcac atcatcattt gctattgact
    13561 catcttttaa tttaaaacgt agcctcgtta tacagtgaga taaactgcta atattatcct
    13621 ttcctcctac attcgcaatg atttcttttg atagttgttc atactttctc attttttctc
    13681 ctccattttc tttttgaaat atgaaggttt ggccaactta atgtcaccac ccaatatata
    13741 taaacctaat tattaggatt tatatctgac ttaatacttt tacttaccac tctttcaacg
    13801 tgaatagtta agtataattt ttcctcatct gttaaatcgt agttgtattt tttatgtata
    13861 aattcatcca acttttctat gaatttataa gcatttttat atttaacttt tattacattt
    13921 aataaatcat cttcattatt ttcatgtaaa ttattactaa caattcgttc tgcaaaatac
    13981 tttaagtgag taataaatct atgataataa actgaatctt catcaaatac tattctgtaa
    14041 tggtatttaa ccatatttga aatttcttgt attatttgtg taatctcata tatagttttt
    14101 atactttgat ccatttgtgc attaactata tgcagtgcta taaatccagc ttcatcttct
    14161 gatagtctaa tttcaaattt tttttctata taatccaatg cctctaaccc tattttaaat
    14221 tcactcttat aaaatctttt tatatcccaa agtaatacat tttttacact tactccttca
    14281 cgagctcttt ctattgcagt atacatatgg tctgttaaag aaatataaat actatcattt
    14341 aatcttttcc ctagtttttc tttagcatat aaaattattt catctgataa ttccatatat
    14401 cttataggaa tatctgctat tagttcttta aatttatcag atatatttgg gtctgaaagt
    14461 ttgaatatct tatcaatttt atcctttgat atatgctctc ctgtacgttt tttataagct
    14521 aaacctctcc ccataactac tatttcctta tgattttcat cagttgtaat aattacatta
    14581 ttattgagta ttttttcaat aatcattgtg atgccccctt tattagcatt aagttaaaat
    14641 aaatcttttt taattattta gaatatttaa aatgtaattt attacataaa aaaaaaccta
    14701 tttattacac attaaataga ctcccatgag tcctgagtaa taaataggtt tagcttgtat
    14761 ttaaacaatc actatccgtt tgtattttat tttaattatt atttattata tgttagcaaa
    14821 tttatttttt agtgtcaact ttttctcaat attttaattt taaataaatt atataaattg
    14881 aatcttcaaa gtactatttt tatcaataaa caaaataaaa aaggtattac tttctttaag
    14941 taatacccat ttatttttaa tttaagtggt ttttcttaat ctcatcaagt agtccatctt
    15001 ctaaataaat ttctaatgca catcctacca ttgcctttac tgctttgtga agtttatcat
    15061 aagcttcctc agaatttgca taatttagaa attctttttc atgaacatat accattggac
    15121 ttatatctaa ggctatttct gtatacatag tagggcaaac ttgacttaca ttacctatat
    15181 ctgtagaacc tactggacca tctttacctt ctaatatatc tgttatacct gcctcaatca
    15241 aattattctt tgttatcttt tgaagtactt tgttatttat tatgttgtca aaagaatttt
    15301 caaagtatct ataagaaagc ttagctcctg tcattaactc tgcacctttt gcacagttta
    15361 taactttttt agttacttca tctaaataac ttctttcagc agctcttacg aaaaacttac
    15421 aagctgcttt ttctggaact atatttggag cctctcctcc atttgaaact ataccatgta
    15481 ttctaacatc tgattttaca tgttgtctta gtgcatttat cccagcaaaa gtaagttgta
    15541 ctgcatctag tgcattgact cccatatgag ggtgactagc tgcatgtgct gatacccctt
    15601 caaaactaaa ctctaatgaa tctatcgcca aagccttaca gtttatatta ttaaaagctt
    15661 ctatatgcat ttgataactt acatcaacat catcaaaagc tcctgcctta actaaatcac
    15721 attttcctcc tgttgtttct tcagctggtg ttcctattag tacaattttt cctttaaaat
    15781 tttcttttaa cttacttaat actatacaag ctcctagtgt agatgctgca atccagttat
    15841 gtccacaagc atgagctggt tctttatttt ctccatatcc aggaagtgca tcatactcag
    15901 ctaaaaatgc tatggtaggt ccatcattat ctcctaattc agctctaaaa gcagtctcca
    15961 tattacaata tggataaact gtatcaaatc catattcctt cattttttct actaagtatt
    16021 ttgatgatat gtattcttct tcccctaatt caggattgtt aaatataaaa ttacaaactt
    16081 cttcaatttc ttttccaagt tcattctcta tctcataagc tctcttcttt atactctcta
    16141 tcataattta cctcctacta gaatcctaga tataatccta ttgtcaaaaa tgccattaca
    16201 agaattgtta atactaccat taaaggaatt acgaatctaa cccactttga ccaaggaata
    16261 ttggctactg ctagtgctcc cattaaaaca cctgatgtag gtgttatcaa gttagttaca
    16321 cctataccaa attgataagc tgtaactatc atttgtcttg atacatctac taagtcgcca
    16381 agtggtgcaa gtacaggtat tgtaagtgat gcaagccctg atgctgatgg tattaaaaat
    16441 gctattaatc cttctattaa gaaagttaaa tttataaata tagtttttgg taatccattt
    16501 aataaatttg ctgcagaatt taaaattgta tctattataa atccattttc tgctattatt
    16561 acgattccac gtgcaaatgc tatacacaat cctgctgtaa ttaaatctcc tgctccactt
    16621 ataaatgaat taactatctc atcttgttta agccctgatg ctattcctga tattatacct
    16681 atagctgtaa atatcattgc aatttcagtt atgtaccatt ctagtcttaa aactccatat
    16741 atcataatcg ccatacctat tgtgaaaatg gctattacca tggcttctct ttttgtaaat
    16801 tcctttatat ttgtatcact attaaccatt aattcttgat ttagtgatat atcatgtact
    16861 aaagattttt tagggtcttt tttaacttta ttggcataca tcataacaaa tcctatagat
    16921 atagccatat atattataaa cataacaact ctaaactcta ttccagaacc tggtactatt
    16981 tgtgataatg cttgtgctat tcctacagag aaaggattcg tagtagctgc tccaaatcca
    17041 gctgttgctc ctataaatac tgtggccact gctgtcaatg aatcatatcc catactggtc
    17101 ataagtggaa taaatatcat ataaaaaggt agtgtctctt cactcattcc aaacgtcgtc
    17161 ccacctagtc caaatagaat cattgaaatc ggtattatta aaaattgaaa cttcttcatt
    17221 ttatttacag tatgagctat aacagcttct atagctcctg ttttattaac tatcccaaaa
    17281 gctcctccaa ctattaaaac aaatccaact acttcagctg catctataaa cccgtttata
    17341 ggtgctgtaa atacatcagt aattccttgt ggatttgatg gtgctttttc ataagttcca
    17401 gctacaacaa ctgaccttcc gtctatatct actctttcaa aatttccact tggcactatc
    17461 caagtaagaa ttgccattaa cactattagc aaaaatatta ttgtaagtgt ctgtggcata
    17521 gtaaactttt tcttttttaa actgctcatt tttaatctcc ccacttttta aattaaatat
    17581 tttattattg catcccttta tcctattttg tatagatgta aaaaagctca acatggatac
    17641 atgttgagct aaatgtgcta aatacaacat acctgcatct tccctttatc ttgtttaaga
    17701 tagctctcca tcaaaattcg ggataatttt gatgacagta ctgtacctat taaatacagt
    17761 cccagcacta gcttcggaca ctagcacttc ggcacttact ccttttatat tgcctcattg
    17821 gtttccaacc tcttcaatat taatcttagt aaatgcaacc tctacctcaa tctgtttgtt
    17881 agatgaggta attcttatta atttttatta attcaaagta attgtagcat aatatgtcga
    17941 gattgtaaat attttcagta taataattct tactttatga tttcattcca tttttcacaa
    18001 ataatttttt ctccatataa tttaaatact gtagtatatt ttaaatacac acaaactttc
    18061 cacaaatttt aaattattat aataccttta taataaaaaa taaaagctat gtaaacttat
    18121 caatttacac agctttatat acattaatct actccaagta cagctttaag ctttgatgct
    18181 attgtaataa ctcgtggacc aaatataact tgaactgagt ttttcttttt aacaactcca
    18241 cttgcaccca attcatttac ccagaagcca tcttcataga atccatcaat tgaatttagc
    18301 tctaccctaa gtctagttgc acagtttgta acatttttta tattattact tcctcctaaa
    18361 ccttctatta tagaatgtac aagctttgta tctttatcat ctacttcctc ttctactgca
    18421 ttgttgtatg ctgttttacc agcatctaca gattgtcttt ctctatattc tttcttacta
    18481 taaagcttaa cttcttctga acttcttcct ggtgttttta tatcaaactt cttgattgcc
    18541 catgtaaata ttatataagt aactataaaa aatattggta tcaaaaataa taatggtaac
    18601 gcatccactt tttgtggttg taataaatta ggaaacatat ttctaaatga ttctcccatt
    18661 atagaaacat taaacatttc tgtaaataca tacgtcaatc ctgccagtgg tacatatgct
    18721 acaaaataca ataatggtgc aacaaatagg aatgtatact ctattggttc cgttacccct
    18781 accaacatgg ctgttactat tgctggtatc aatatactta ttgctttttt cttattagca
    18841 ttatcagcca acttatacat agctaaagct gctgctggta atattgcaaa atgtattaat
    18901 aaacgacctg ttgtgaagtt acgagttata taagatagtg tatctgggtc tcccatttga
    18961 gctaatctta tattattaac accctcgtaa attgctccac ctacttccat tgttccacct
    19021 actcttgtat attctatagg gaatgcaatt aagtgatgta taccaaatgg taataatgct
    19081 ttatccattg ctccaaaagt aaatgttcct aataatccac tagaacctat ccaattacca
    19141 agtttagata atgccaaccc tactggtggc catataaagt acattgctgt acccaatact
    19201 attgatgcta taaacatcat aatcattgaa aatcttggac ctgagaaaaa agataatgca
    19261 ctaggaagtt ctatgtcaac aaatttgtta tgtactgcac tagctacaaa tccagctatt
    19321 atagctccaa atatactaca atcatatgaa aagattccta agaaagaacc atataaagaa
    19381 cttcgactat atgcttctgc ctctcctaat ccagatgcca taaacgcttc tgctgtaact
    19441 gtatctgaat ttataccatt tgctgctaac aatgtactta taactgtgtg cattcctata
    19501 aataaaacaa ttcctcctaa tgcaccccat cctttttcct ttttagataa tccaaaggct
    19561 atacctgtaa caaagaatat tggtaagtat ctcattacca taaatcctaa atcgtttatt
    19621 actttaaaga atacatttat aaatgaccct tcttttatta gtccgctaag ccctaatgca
    19681 gaaacgtttt ccatatttgc aaaagctgac cctaatccta taaatactcc tgctacaaca
    19741 agtaatataa caggtatcat cattgctcca gaaagtactt gtaatttatc cttcatagta
    19801 ttatttcctc catttttatt gaaatgccag gctatataat gcatatatat atacttctat
    19861 tgctttgtat aatgtatcta tacttatatt ttcatttgcc tgatgtgaat ttggattatc
    19921 cccctctatt gtgggtccaa atgcaactcc attttttaac actcttgcat aagatgcagc
    19981 tccttttgta aaaagttcgg cttcttttcc aaaaccttgt ttatatgcat ttgataattt
    20041 atttattaat tcactatctg gttttacata cagtaatttt aaatccttat atatatcaac
    20101 tattaaattt tctttttttc caatttcatt aattctatta gttataaact cccaacttat
    20161 acccttagga tatctaaagt ctattttcat attcaattca tttttctcta agaagatact
    20221 cattatacat attgtagaaa ctcccatatc tacatcttct ttatacatcc ctaatttttt
    20281 tccatgatta tcatctgtaa agtatgaatt taaaatatcc cttattataa cgcctttatc
    20341 atttagtttt ttaattttct ctaaatcttt tgctaaacta aatgcacagt tatatgacct
    20401 gtgtggattt ctcgataaag ccctttctcc tgtatatctt actaatactt taccttcatc
    20461 taattcttct atctctgtat aataagctaa tgattctact aaatctttct tatcattagt
    20521 tttaaaaaca gcctcaattt tgtcacatac aaatccatct tctttgtttg actttatatc
    20581 aactaaattg tgatttctaa atttatcttt atctattttc tttcttagat tgaagtataa
    20641 aatacctttt tctccattta ctattgggaa gtttccatct ggagaaaatg caaattttgg
    20701 ctgttcattg acactaaagt aatgctccat acattcccaa gtcgtctctt cagctccacc
    20761 cactatcaat ctaatctttc tcttcggctt ttcattaagt tctcttaaga aaagtaatgc
    20821 atataaaatc cctatcaaag gtcctttgtt gtcattaact cctctaccat aaagatagtt
    20881 atctttttga catactttaa aaggtttact cttccaaagt tctttattat atattggcac
    20941 cacatctata tgattaagca cccctactac ttcttctcct tctccatatt ctatatgaat
    21001 tgcatatcca tcaaagtctt ttacaacaaa atctttgtct tttgctattt gaataagctt
    21061 atcgaaggca tttcttattt ctatcccaaa tggttgattt atatctgttg tactttcatc
    21121 tctaattgaa ggtatttcaa ctaaacttct aatatcattt atgatatttt cttgattgga
    21181 ttttaaataa tcaataatta gttctttgtt tactatcatc ttaattattt atcacccctt
    21241 tatattaatt ttacaaagca tttcagttca tatctacatt ataaattttg aatattattt
    21301 tttcaatatt tcaaatactt ctctaagtta ccataatgat acggtaaaca atcaacagat
    21361 tatgacaaaa tcatactata cctattacta atattttaac ttatctatta cgtctttttt
    21421 aatgtaagtt tattccaaaa atacataaaa aaagatgtag ccttagctac atcttcttat
    21481 atctattcaa cttccattat tatgctatta atatctacat ttccaggttc tatcctatct
    21541 tttactgttc tcttaacaga atcagcatca tccattataa ctacaggagt tattatattt
    21601 aaatcatttg acgttataaa atctaaatct acttccatta ttaaatcttt agcttttacc
    21661 ttatctcctg cctttacctt aacatcaaac ggctttcctt ctagtgacat tgtctctaaa
    21721 cctacatgta ttaatatatt tgtattatca ttactcttaa tcattattgc atgctttgta
    21781 tcaaatacat tgactatttc accatcaaca ggagaatata acttaccttc acttggtatt
    21841 attgctactc catctcccat catcttttgg gcaaaaactg catctggaac atcttctaag
    21901 ttcactaaat ttcccttaaa agggctatat attttctcaa tcttattttc ttttttctta
    21961 aatatattaa acataacaca ctctccacat tataaaattt tatgataata tttttcttaa
    22021 agcttttgct acaccatcat ttacattagt atcagttaca aaatctgcca tagattttac
    22081 ttcatctgta gcatttccca tagcaatacc aagacctgca aatttaatca tggatatatc
    22141 attttcatta tcacctatac aaataacttc tttgctatct atacctaata tatcacaaaa
    22201 ttttttaact gcaatacctt ttgaagtacc tttactcata acttcaaagt ttatctttcc
    22261 agaacttact acttctaaat cttcttgttt tttaaattct tcctttgctt ctctcaaaga
    22321 atctacgttt tctgagaaaa gtatacattt taaaatttca ttatcagctt tttctaataa
    22381 agtttcacaa cttgcatttt ctattatttc aattctgtct tcttctttat ttttactatt
    22441 tattaatcta tatggatgtt cttcacctat ttcattgttg gatataacta ttttacagcc
    22501 tttaaaatgt ttgtttaaat tatacttttc acctattgta tagattttct ttagagcttc
    22561 tttgctcaaa accttcttat actcatatcc cagtaattta aaatatgtcc cattagttga
    22621 tataatatat atatcatccc ctaaaacact tgtaaaatat ttcatagcat tataaggtct
    22681 tcccgtaact aaggctacct tgataccctt ttccatggct tcttttagtg ctttaatatt
    22741 ttcttctgat acttcaaatc ctttacccat caaagtacca tccatatcag tacaaattaa
    22801 tttatatcgc atttgtatca catcctagta agatttttct aatatttcaa caaggtcttc
    22861 tttctttcca aaaggtaaaa atcctaaaac tggacagctt gttatttgtt ctaattgttc
    22921 ctttgttaca ttaaactcag acatttttgt cttaagcccc actctcttta aaaaactttc
    22981 tatttcattt cctaaagttt tagctgcttc atcatcttcc actttttcta attcttggtt
    23041 tagtattctc gctactttgg caaatttctc tatattatcc ttatagaact tttctgcaaa
    23101 ttttgggaac actatagcca aagcctcacc atgaggaata tgtgtaactc ctcctattat
    23161 ttcacttagt ggatgtggtg ctgctgctcc agcatttgcc agtgaacttc ctcctaatgt
    23221 atctgctact gctaactttg ttctgtattc tatattattt ttatcttcca ttactttagg
    23281 tagatagtta atgactaatt ccatagattt ttcagacatt atctctgtaa aatcattagc
    23341 atttggattt atataacttt caaatgcatg agtaaaagca tcaaatgctg ttgatgcagt
    23401 aattctctct ggcagagtta acataagctc tgggtcaact atacattctt ttgagaaaca
    23461 attttgatga aatattgtat ttttctcgct tcctctcgat attactgctg cttgtgtaac
    23521 ttggcttcct gttccagaag tagttgatac agctattaat ggtaattctt tttcacttac
    23581 cttatcgtat attttaaatg gatttgtata tgtactaaac atataatccc aatctatttt
    23641 ttctaaacca aaagtcaatg ctaatacttt tgcagtatct atacttgaac ctcctccaac
    23701 agctaaaaca acgtctacag attctttttt agctaattca aacccttcgt ttattaattc
    23761 tacagttggg tttggctcta ctctctgaac ctcccatgac taaagtcaca gggttcctgc
    23821 ttcacagaat tttgcatact aaaatatgtc ttactaattc tccacaggcc atccccgtag
    23881 ttcctacggt tcttacataa gttatttatt ttgaattgtt attagtctta atccttcttt
    23941 taatatattt atacttgcat ttatatctct atcgtgagtt tcattacaac taggacaaat
    24001 ccattctctt atatttaagt ccttcacttc ctcgttttta tacccacatt tattgcatat
    24061 ttgtgaactt gcaaagaatt tacctacctt tacaatttgt ctaccatgcc aattagcctt
    24121 gtattctaat tgacgaataa attctgacca tgatacatct gaaattgagc gagatagttt
    24181 acgattttta atcatattct ttacttgtaa atcttctatg caaataatat cattctcttt
    24241 tattaattta gtagataatt tttgcagaaa atcatttctt tgattagcta tatgttcttg
    24301 aagtcttgca acttttaatc ttgctttatt tctatttaaa ctaccgattg tttttctcga
    24361 taattctctt tgtaatttag caagtttgtt taatgacttc ttaagatact taggattttc
    24421 tataaattct ccacaacttg agatacaaaa ttctttaatt cccaaatcta aacctatatg
    24481 attattagta ttttcaaatg cttcaatatc tacatcagta cagcataatg atacataata
    24541 tctaccactt ggttctttag atatagtagc attaagtatt ctaccttgag gtacttgttt
    24601 atcccttatc ttaaccatac caagtttagg tagttttata tattgaccac aatacataat
    24661 gtttccattt gtaaagttag tttta
//
LOCUS       DAYAOO010000059        24609 bp    DNA     linear   BCT 12-OCT-2024
DEFINITION  TPA_asm: Clostridioides difficile isolate ST8-SSI-h139-18
            SAMN40601845-rid21577343.denovo.059, whole genome shotgun sequence.
ACCESSION   DAYAOO010000059 DAYAOO010000000
VERSION     DAYAOO010000059.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN40601845
            Sequence Read Archive: SRR28438827
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 24609)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 24609)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-MAY-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-MAY-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002157583.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002157583.1
            Genome Coverage       :: 163x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/11/2024 16:19:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 4,038
            CDSs (total)                      :: 3,963
            Genes (coding)                    :: 3,930
            CDSs (with protein)               :: 3,930
            Genes (RNA)                       :: 75
            rRNAs                             :: 6, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 60
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 33
            CDSs (without protein)            :: 33
            Pseudo Genes (ambiguous residues) :: 0 of 33
            Pseudo Genes (frameshifted)       :: 7 of 33
            Pseudo Genes (incomplete)         :: 25 of 33
            Pseudo Genes (internal stop)      :: 11 of 33
            Pseudo Genes (multiple problems)  :: 8 of 33
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..24609
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN40601845-rid21577343.denovo.059"
                     /isolate="ST8-SSI-h139-18"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Denmark"
                     /collection_date="2018"
                     /collected_by="Statens Serum Institute"
     gene            complement(62..898)
                     /gene="nadC"
                     /locus_tag="ACGI5H_002574"
     CDS             complement(62..898)
                     /gene="nadC"
                     /locus_tag="ACGI5H_002574"
                     /EC_number="2.4.2.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454666.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004514 - nicotinate-nucleotide
                     diphosphorylase (carboxylating) activity [Evidence IEA];
                     GO_process: GO:0009435 - NAD biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="carboxylating nicotinate-nucleotide
                     diphosphorylase"
                     /protein_id="HFG9698273.1"
                     /translation="MNYLIIDRMIQDALIEDVPSEDITTNSIVDENSKSTVDLICKQD
                     GIIAGLGVFKRVFEILGDVDVKLYKNDGDRVKNREKIAVLTGSTRNLLVGERVALNYL
                     QRMSGIATITSRYVEKLEGTNTKLLDSRKTIPNLRILDKYSVKVGGGCNHRFNLSDGI
                     LLKDNHIGAAGSVKKAVELARKNTSFVRKIEVEVETLDMVKEAIEANADIIMLDNMSL
                     EMAKQAVDIINGRAIVEFSGNVNLDTIEDIGKIGVDVVSVGALTHSVKALDISMKNLR
                     NI"
     gene            complement(879..2180)
                     /locus_tag="ACGI5H_002575"
     CDS             complement(879..2180)
                     /locus_tag="ACGI5H_002575"
                     /EC_number="1.4.3.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903160.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008734 - L-aspartate oxidase activity
                     [Evidence IEA];
                     GO_process: GO:0009435 - NAD biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="L-aspartate oxidase"
                     /protein_id="HFG9698274.1"
                     /translation="MNLEQDVLIVGSGVSGLYCALNLDKSLNVLVVSKSTIENNNTYL
                     AQGGISTARNIDDIKSFVEDTMKAGQYKNRVEAVQVLADESIENVGQIVEYGMPLDKE
                     NGEIDYTREGAHSVNRIVHSKDNTGEVVFKTLLKEAKTRENITLIEDAYLLDILKDGN
                     KCIGARIFKSKKEIHVFSKIVVLATGGIGGLFKNSTNQRHLTGDGIAIALRNNIKIEN
                     LEYIQIHPTAFYEENNEGRRMLISESLRGEGAKLLNKNKERFVDELLPRDVVSKAIFE
                     QMEKDKLPYVYLDATHLDSEYLINRFSFIYNECLARGTDITKECIKVSPAQHYFMGGI
                     HVDLDSKTSMENLYAVGEISCTGVHGANRLASNSLLEGLVFSKRAAKNINSVIDNVKV
                     KFIDVPDMDIDIEQVKKENKILVIKEIERTSEDFGDELFDY"
     gene            complement(2193..3107)
                     /gene="nadA"
                     /locus_tag="ACGI5H_002576"
     CDS             complement(2193..3107)
                     /gene="nadA"
                     /locus_tag="ACGI5H_002576"
                     /EC_number="2.5.1.72"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416811.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008987 - quinolinate synthetase A
                     activity [Evidence IEA];
                     GO_function: GO:0051539 - 4 iron, 4 sulfur cluster binding
                     [Evidence IEA];
                     GO_process: GO:0009435 - NAD biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="quinolinate synthase NadA"
                     /protein_id="HFG9698275.1"
                     /translation="MDKDLTYQIKELKKEKNAIILAHFYQPPEIQELADAVGDSYYLS
                     EIARDCKEEVVVFCGVRFMGESAKILSPEKTVLMPVSNAGCAMADMVDEEGVIKLKQQ
                     YPNALVVCYINSTAKVKAHCDVSVTSSSAIKILENIDNKEIIFLPDKNLGGYIAEQFP
                     DKNFIFWDGYCKYHNNIRAEEIIELKDKYKNAEVLVHPECKKEIRDLGDYVGSTSGII
                     KYATNSKNKDFIIATEEGILHELKKNNPNKNFYIPGGKILCTDMKKTTLENLYSTLKN
                     MENEVIVEDEIMEKALNSLLNMHKLAEG"
     gene            3525..4982
                     /locus_tag="ACGI5H_002577"
     CDS             3525..4982
                     /locus_tag="ACGI5H_002577"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890565.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_process: GO:0009267 - cellular response to starvation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="carbon starvation CstA family protein"
                     /protein_id="HFG9698276.1"
                     /translation="MTTFLIGLAILLIGGALYGAYCEKVFGPDDRKTPALAQSDGVDY
                     VPMKKWKNSLIELLNIAGTGPILGPIQGILFGPIAFILIPIGCVFGGALHDYMSGMIS
                     IREKGAQMPSLISRFLGNKVFQVYNIFLCLLMLLVGAVFIYTPGDLVVTQILNMKSTI
                     NNPVVWIVYGLIFLYYLCATLFPIDKIIGKVYPIFGAILLLSAAGVGIGIFTQGYDLA
                     NLSLANWKGIHPDGIPLIPTFFVTVACGIVSGFHSTQATLIARSVSNEKEGKTTFYNM
                     MILEGLIAMIWAAAAMGIYNKGIPKELVGSPDVIGLVARDLLGSIGGIIAIIGVIVLP
                     ITSGDTALRSLRLMLADYFHYDQKEKKHRVILSICIFIPVIAILIFAKLSASGFNILW
                     RYFSWSNQTIAIFAFAMITVYLIIKEKNYIISLIPGMFYSFVIFSYIFNAQIGFNLNI
                     NISYVLAAIFTVLYAILTVRSGRKLKSKADTKLAD"
     gene            5205..5633
                     /locus_tag="ACGI5H_002578"
     CDS             5205..5633
                     /locus_tag="ACGI5H_002578"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430796.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9698277.1"
                     /translation="MNNKLHELEKNLPETSCSFCTHLSFKGPSLDYRYDIRCVISDTK
                     PDFRGCCEYFEPEYTELNTGDLDNLYINFLETCLKVNYNDYINSMYWKLFKERTLLEN
                     NFKCSICGSTENVDVYHVNKNLGRETSKDVVVKCDKCNCK"
     gene            5693..6001
                     /locus_tag="ACGI5H_002579"
     CDS             5693..6001
                     /locus_tag="ACGI5H_002579"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430798.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1540 domain-containing protein"
                     /protein_id="HFG9698278.1"
                     /translation="MKNNNLNCAATNCAYNTSGYCYAGSIKVDGMQATTTENTYCASF
                     EDKYTSGITSRSNETNQVDTDNIHCEAVKCKYNKNELCKAEKVHINERNASCETFEMK
                     "
     gene            complement(6148..7170)
                     /locus_tag="ACGI5H_002580"
     CDS             complement(6148..7170)
                     /locus_tag="ACGI5H_002580"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416801.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0015562 - efflux transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:1905887 - autoinducer AI-2 transmembrane
                     transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="AI-2E family transporter"
                     /protein_id="HFG9698279.1"
                     /translation="MEDNKGLARDSSKYKIVSISVVVIILITFWYMLNMVLLTFIMTF
                     IFYNLLVATRKRIKKFSSLNIPDSLIIIVLYALFAILLVLISYAVVPIIIVQLTELSR
                     VFSDFDVNQFAQSLGPKLYPIVSKLDFNKYISQAGLLIASTATKVGSFGVNILLAFLL
                     SLLLLLEKNEIKNFGDKLSDSKISFIYNSLVFFGKSFVKNFGEVMKVQVMIAFINSVV
                     SMIFLGFMGFPQIWALGFMIFVLGLIPVAGVIVSLIPLTVIAFNTGGITKVFGVLLMI
                     CIVHAVETYILNPKLMSNRTKLPVCFVFIILLVGEHYLGVWGLLIGVPIFMFLMDILG
                     VKFTSR"
     gene            complement(7345..7851)
                     /locus_tag="ACGI5H_002581"
     CDS             complement(7345..7851)
                     /locus_tag="ACGI5H_002581"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416798.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX domain-containing protein"
                     /protein_id="HFG9698280.1"
                     /translation="MELWDLYNADGIKTGNVIKRGNSIEEGYYHLAVEVWILNSNSQI
                     LIQKRSKSKKTLPNMWGMTTGCIVSGEDSLEGAIREAKEEIGIDITKDEMKVFRSMIH
                     EDTLWDVYLVKKEYDISKAILQEEEVSDIKWVSTDEIRQLLKEGLFFEYPEIYELLYE
                     IDNNKLNI"
     gene            complement(7911..8612)
                     /locus_tag="ACGI5H_002582"
     CDS             complement(7911..8612)
                     /locus_tag="ACGI5H_002582"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416796.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HFG9698281.1"
                     /translation="MGKISLKSMIRLFSGFFIFAISSVLMINAHVGLMPWDVLHQGLS
                     IKLGITIGQASIMVGVVIVILDAVFGENIGWGTLLNMTFIGIFIDLVIFSGVIPHASN
                     TYIGVFMVVIGIILAAIASFLYLGVCLGSGPRDGLMIALQKKTNKSVRLVRTILEILA
                     LVVGWLLGGSVGIGTLVSALGLGYVLQIVFRIFKFDTKLLKHRFIIDDIREWKEKKSN
                     EHKCKSSIVIKNEQN"
     gene            complement(8830..9900)
                     /gene="buk"
                     /locus_tag="ACGI5H_002583"
     CDS             complement(8830..9900)
                     /gene="buk"
                     /locus_tag="ACGI5H_002583"
                     /EC_number="2.7.2.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454677.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0047761 - butyrate kinase activity
                     [Evidence IEA];
                     GO_process: GO:0006113 - fermentation [Evidence IEA];
                     GO_process: GO:0016310 - phosphorylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="butyrate kinase"
                     /protein_id="HFG9698282.1"
                     /translation="MTYRILAINPGSTSTKIAVYDGEEQILVKTIDHPAEEIAKYNTI
                     QDQFEMRKEAVLNILKENSIDLKSLSAIVGRGGVLPPVKSGAYLVNEEMIDVLRHRPV
                     LEHASNLGAVVAHAISEPLGINSYIYDSVAVDELIDVARISGLCGMDRSSAGHALNTR
                     AMALKYAKDKGKDYKSLNLIVAHIGGGVSIYLHEKGRMVDMLSDDEGPFSPERSGRVP
                     ATKLVAACYSGQYSEREMTKKIRGKGGIVSYLNTVDAREVEKMIAEGNEEAKIIYEAM
                     AYQLAKGIGELATVVDGKVDAIIITGGIAYSEMFTSMVKKKVEFIAPVEIMAGENELE
                     SLAFGTLRVLNGEEEARIYSEN"
     gene            complement(9953..10528)
                     /locus_tag="ACGI5H_002584"
     CDS             complement(9953..10528)
                     /locus_tag="ACGI5H_002584"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430806.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="indolepyruvate oxidoreductase subunit beta"
                     /protein_id="HFG9698283.1"
                     /translation="MTKSILLVGVGGQGTILASKLLTMGLMEAGYDVKMSEIHGMSQR
                     GGSVSSQVRYGDCVHSPVIEIGGADILVSFEKMEALRWFNYLKPEGKALVNNHRIDSM
                     TVLIGGAEYQESDIDAELSRLNAKVINAADKAEELGNSKIMNVILLGCLVKSMQLESI
                     DWEKIISENVKPKFVELNIKAFHEGMEMVSK"
     gene            complement(10530..12317)
                     /gene="iorA"
                     /locus_tag="ACGI5H_002585"
     CDS             complement(10530..12317)
                     /gene="iorA"
                     /locus_tag="ACGI5H_002585"
                     /EC_number="1.2.7.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416787.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0043805 - indolepyruvate ferredoxin
                     oxidoreductase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="indolepyruvate ferredoxin oxidoreductase subunit
                     alpha"
                     /protein_id="HFG9698284.1"
                     /translation="MKQLMTGNEAIARGAYEAGVKYASAYPGTPSTEILENIATYKDA
                     IVAEWAPNEKVALEAAIGGSIAGARTMASMKHVGLNVAADPIFTYAYTGVNGGMVLIT
                     ADEPGMHSSQNEQDNRMYAKFAKIPLFEPSTSQEAKDMIKEAFEVSEKYDTPVLYRVT
                     TRLCHSKGLVECYDREEVEIKEYVKNAKKMVTVPANAQIRRGVVEERMEILKKFSNET
                     DLNYYEINDTKIGVIASGMCCNFAKEVFGKNASYMKLGFTNPLPYEKIKEFAEKVDKI
                     YVIEENDPFIEEQIKAYGIDCIGKDVIPPYGEMTPDVLRKAIFGKTNDTIEYKSELVT
                     PRPPSFCAGCPHRGFFYELGKRKNLIVGGDIGCYTLGFAPPYNGIDYVVCMGSAFGTA
                     HGAQKVLNMKDDNEKRLVGVLGDSTFFHTGINGLLDVVYNRGNSISVILDNRITGMTG
                     HQENPGSGYTLQGAKTKEVDIEGLVKACGIEHVRVINPNNLKEVNEALDWALAIEDEP
                     SVIITRWPCVLKKFSKEDIEEFNNPFKTKCKVDHDKCIGCKLCLKTGCPALSFDKENK
                     LSNIDRNQCVGCGVCAQVCPKQAIVKEEK"
     gene            complement(12378..13637)
                     /locus_tag="ACGI5H_002586"
     CDS             complement(12378..13637)
                     /locus_tag="ACGI5H_002586"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430809.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA];
                     GO_process: GO:0009058 - biosynthetic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="aminotransferase class I/II-fold pyridoxal
                     phosphate-dependent enzyme"
                     /protein_id="HFG9698285.1"
                     /translation="MSQSMVGKHAMWPKENDVIFSISGRAQAAEKAFGMDNVINATIG
                     ALMDDSGKLITMKTVYEEYKALDNCEIGAYAALEGQPDYLEAVKKVFFRDYLPEGHIR
                     VLASPGGSGAIKLAVWNYTNEGDEVLTSDWFWSPYVSIAEEANRKVVNYQLFDENRRF
                     NFESFKEKFVNIAEKQGRVFTIINTPAHNPTGYSVADDEWDKILDLSKEVAKDKDKKI
                     IFFVDSAYIDFAGDDDVCRKFFKKFSNLPENVLVLVGFSMSKGFTAYGMRMGAIICIS
                     SSEDVAEEFHYSCVHSCRANWSNCNRSAMAVLSNIVNDPKKFKEYEDEKEIYKNMLTR
                     RADVFVKEAERVGLEILPYIAGFFVSIPCDNPKEVCEELTKHNLFAVPLKMGLRFAVC
                     AVSEDKCKKAPSIIKEALESLEVKINN"
     gene            complement(13899..15899)
                     /locus_tag="ACGI5H_002587"
     CDS             complement(13899..15899)
                     /locus_tag="ACGI5H_002587"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454679.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0008134 - transcription factor binding
                     [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sigma 54-interacting transcriptional regulator"
                     /protein_id="HFG9698286.1"
                     /translation="MILLRKKIGIIASDIELKERIEELYREDVENGTIIIDILNLDLM
                     ENQGRILVEKGAQAIIGRGGGYSLVIDTVNVPVIPMNMKSTDLLRAIEIAKKYSKKVV
                     LILGDNEVSFDYVGWRNVISTEITEEWFESKYEIRSKVVKYIDQKDEVVIVGGGLACS
                     FARQYGIDSVFATASDESIREAVEYCKKLLDTLGEEKFNNEVLRNILDGIKDGVIAID
                     SNGSIILYNESAKNMLKVERKCALNKYILDVFPKMEWMLDCLHEKEDVEDRKIRNINN
                     LIVNTRTTLIKVDNSTYGVLGIIQDITKLQNLERKIRFDLNQKGLYARYTFDDFLFKD
                     KLTKEFIEEAKKIGKSDYTTLLYGESGSGKEIIAHSIHNISKRKDRPFVAINCATIAE
                     NLLESELFGYEEGAFTGARKGGKRGLFELAHGGTLFLDEINSLSFNIQTKLLRVIEER
                     QIMRIGSDYIIPLDIRIIAATNESLTEKIVMGTFRADLFYRLSSLEINIPPLRDRRED
                     IIPLFNNFVNEVLKDDGLNGINSIDENFVLTKDEMDKLYNYSWPGNVRELKTIAQKYV
                     VTGKIKLRQDRDFKTKKLLPNSEVDKFNSETTASVEVQDESINISKINDGKISIDIKE
                     VNKYVEEKIISMLFAQGLSKNEVAQVLGISRTSLWKKYNKNI"
     gene            complement(15907..17737)
                     /locus_tag="ACGI5H_002588"
                     /pseudo
     CDS             complement(15907..17737)
                     /locus_tag="ACGI5H_002588"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454680.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_function: GO:0052621 - diguanylate cyclase activity
                     [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="diguanylate cyclase"
     gene            complement(17821..19662)
                     /locus_tag="ACGI5H_002589"
     CDS             complement(17821..19662)
                     /locus_tag="ACGI5H_002589"
                     /EC_number="2.7.7.65"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903172.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GGDEF domain-containing protein"
                     /protein_id="HFG9698287.1"
                     /translation="MEEIDDTILDSMFKLTLNERLLTNNDFIENKIDVVKNLIDCYKT
                     EQNSLMLLKSNFLLALLYGIQGFSEKMKEYILISCKYIDKCLPKDYKFLARFYSQIAI
                     LSLKNEDVNKANLYMDKFNLICDENNFLIEEIIFKSQLIYIKASKCIESSVIIKEIET
                     LYIKIKEINDFNCKKIYFFIIGKIYFLFLDDALIAKVNFLKARKYADLLKDMQVSSLC
                     NIKIGECECSFENYECSMEYFNEVISNKKYRNVNIIQKYRASNNITKILIKTRNYPVA
                     INNLAKSEVYLEKIKNHSLKEVEKFDLFISLAMYYAKSNEKSFEQSICYLDRAKNILN
                     MIKNIEEYIIYDLEIIYHQAKIYYIFGYYDNALNTNKKLLEKSKNAKNYNYVKLAYKS
                     IYLCFEKIQNYEMSMKYFKMYYELKMMYIKARNRNYIDSLNYRHEYIEKEINNMRKVK
                     LDLDKKKYVDHLTSAYNRTFLNDFLEKQEVSEYCTAFMIDVDYFKEYNDTYGHYNGDI
                     ALKNITIIIKKYLKKDMLMIRYGGEEFLILSVCKDYKKSKIFGRKLCRIVKKFLNNNL
                     TVSIGIDTCKNSSIDIKEIIENADKALYKAKESGRNRCLHYHDFKNF"
     gene            complement(19793..20212)
                     /locus_tag="ACGI5H_002590"
     CDS             complement(19793..20212)
                     /locus_tag="ACGI5H_002590"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430813.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3785 domain-containing protein"
                     /protein_id="HFG9698288.1"
                     /translation="MSLYKFIYDDKEYLLKEENCSALINDEENPVQGVSISKIIDILN
                     EAEEVDFDVEYYQEACPLCLEGVKEKKKFFPFLEYHFYIFSKDGEYVISNISVDYKGL
                     SFNKLSRANKVDNSYIVSVIICENCQDYIVQIENCIV"
     gene            20525..20707
                     /locus_tag="ACGI5H_002591"
     CDS             20525..20707
                     /locus_tag="ACGI5H_002591"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9698289.1"
                     /translation="MYKDKSDECIHLMTAYIDSISGYYSFIDTQLEDFMMKYGENIVD
                     SNLHSIMMLLCKWGLS"
     gene            21036..22058
                     /locus_tag="ACGI5H_002592"
     CDS             21036..22058
                     /locus_tag="ACGI5H_002592"
                     /EC_number="1.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903176.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0010181 - FMN binding [Evidence IEA];
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-hydroxy-acid oxidizing protein"
                     /protein_id="HFG9698290.1"
                     /translation="MDYNDLLKSARENFNGTCKVCKICNGLACAGDVPGMGGKGSGSS
                     FIENRKSLEKIKINMRVIHNVSKPDTSIELFGRKMSSPIFAAPVSGTILNMGGKVSEK
                     EYIEPVVRGCSNSGIYAMVGDTNVDTFLLDNLDVLKDNRGNGIVFIKPWNNSKIIDKI
                     RLSEEAGAFAVGVDLDACGLINNQFQENPFSPKTIDEIRELVESTRLPFIIKGIMTVD
                     DALMAVESGASAIIVSNHGGRVLDYTPGTCEVLPDIAKSVKGKITILVDGGVRTGVDV
                     VKMLGLGADAVLMGRPFVTASFGGGLDGVEFFIEKVRNELCETMILTGCQNVKDIDGR
                     VIWNLL"
     gene            complement(22151..22753)
                     /locus_tag="ACGI5H_002593"
     CDS             complement(22151..22753)
                     /locus_tag="ACGI5H_002593"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454685.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidoglycan-binding domain-containing protein"
                     /protein_id="HFG9698291.1"
                     /translation="MLTKLRKIVAIMCCLLLTFTSVAFADTSKEKGGSKETVPEKNLD
                     SFTLSGYIYTYENAPQEIRDEHKQNCEEINIDPKPDDEIFVPESANLMNEDNSKGVYA
                     SYTVSYNIGAKTITIMSNEYLTISTTKVIRKGNSGKEVKAAQIMLTLLGYNVGIDSSF
                     GSKTYNAVVSFQKKYGLSADGIIGPATWDKLGRLTDPTLS"
     gene            complement(22770..23918)
                     /locus_tag="ACGI5H_002594"
     CDS             complement(22770..23918)
                     /locus_tag="ACGI5H_002594"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454686.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M56 family metallopeptidase"
                     /protein_id="HFG9698292.1"
                     /translation="MNNYMLYVFENLIKTTIVCSLGICLLLFLKRYLFKKFSKRFNYY
                     IWLIIVFRMLLFLFNYTIVYEVKEPKENALGNNITQIDISTDNNLMLYVAYLWLFVTI
                     VIAVYTFIKYTRFKNLVVDVSYDIEDNDINCIYKNLLKELNIKKKIELRGSDELISPA
                     GMGLFKSYIFLPDYPYSKDELTWILKHELMHFKNKDILIKFLVLSVRIIYWFNPLVYV
                     MSNKVNLDCELCCDESVLVECSLKDKKEYALALIKSIKFSKNYNSKILTTEFDKTNLE
                     KRLESIVKKKGKSGILIAVLVFMTSITSFVEVDAQVRIDEGNNGMNNNINEFLLNKTT
                     DKIINIYYKDAPNEIRKFYEDKCELEGKIPRDYDIIEMDMKDYNQLIK"
     gene            complement(23911..24288)
                     /locus_tag="ACGI5H_002595"
     CDS             complement(23911..24288)
                     /locus_tag="ACGI5H_002595"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0045892 - negative regulation of
                     DNA-templated transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="BlaI/MecI/CopY family transcriptional regulator"
                     /protein_id="HFG9698293.1"
                     /translation="MMIRKIPQAELKVMKFIWKVDVTVTSKDVIEAMEQKYGWKQTTT
                     LTLLSRLVKRGFLDAQKIDRYTHYTIRVKHKDYLSFETKDFLSNIHDDSLRSLISALH
                     DDENIGKDKLDFLESYFDNLKDE"
BASE COUNT         8084 a         4193 c         2608 g         9724 t
ORIGIN      
        1 cttaaattta taaaacaaat ttaaggagtc tattttaatt aagtttattt caatataaaa
       61 tttatatatt tctcaaattc ttcatactta tatcgagagc tttaacagaa tgtgtaagcg
      121 ctcctacaga aacaacatcc acaccaattt ttcctatatc ttctatagta tctaaattta
      181 catttccgga aaattctaca atggctcttc catttataat atctactgct tgttttgcca
      241 tttccaaact catattatcc aacattatta tatctgcatt agcttctatt gcttctttta
      301 ccatgtctaa agtttccact tccacttcta tctttctaac aaaagaagta ttttttctag
      361 ctaattcaac tgccttctta acactaccag cagccccaat atggttgtct ttaagcaata
      421 ttccatcaga taaattaaat ctatgattgc atcctccacc tactttaaca gaatacttat
      481 ctaatattct aagattaggt atcgtttttc tactatctaa taattttgta tttgtacctt
      541 caagcttttc aacataccta cttgtaatag tagctatacc actcattctc tgtaaataat
      601 tcaatgctac acgctctcct acaagtaagt ttctagtact acctgttaat acagctatct
      661 tttcacgatt ctttactcta tcaccatcat ttttatataa ttttacatct acatcaccaa
      721 gtatctcaaa aactctctta aatacaccta agccagctat tataccatct tgtttacaaa
      781 ttaaatctac agtagattta gaattttcat ccacaataga attagttgtt atatcttcac
      841 ttggaacatc ttctatcaaa gcatcctgta tcattctatc aataatcaaa taattcatcg
      901 ccaaaatcct cacttgttct ttcaatttct tttatgacta atattttatt ttcttttttt
      961 acctgttcta tatctatatc catatctggt acatctataa acttaacttt tacattatct
     1021 ataactgagt ttatattttt agctgctctt tttgaaaata caagcccttc aagtaatgaa
     1081 ttacttgcca atctattggc tccatgaaca cctgtacaac taatttcacc aactgcatat
     1141 aaattttcca tagatgtttt tgaatccaaa tctacatgta tcccgcccat aaaataatgt
     1201 tgtgcaggag atacctttat acattctttc gttatgtctg ttcctctagc taaacattca
     1261 ttataaataa aagaaaatct attaattaaa tattcactat ctaaatgtgt tgcatctaaa
     1321 tacacataag gtaatttatc tttttccatt tgctcaaaaa tagcttttga aactacatct
     1381 ctaggaagaa gttcatccac aaatctttct ttatttttat ttaaaagttt agctccctct
     1441 cctcttaatg attcagatat aagcattctc ctaccttcat tattttcttc ataaaaggct
     1501 gtaggatgta tttgaatata ttctaaattt tctattttta tattatttct taaagctatt
     1561 gcaattccat cacctgtaag atgtctttga ttagtagaat ttttaaaaag cccaccaatt
     1621 ccacctgtag ctaaaactac tatttttgaa aaaacatgaa tctctttttt agatttaaaa
     1681 attctagctc ctatacattt attgccatct tttaatatat ctaaaagata ggcatcttct
     1741 ataagagtta tattttctct agttttagct tcttttaata aagttttaaa aacaacttct
     1801 ccagtattat ccttactatg aactattcga tttacactat gtgctccttc tcttgtgtaa
     1861 tctatctctc cattttcttt gtctaaaggc ataccatatt ctactatctg ccctacattt
     1921 tctatagatt catctgcaag tacttgaact gcttcaactc tatttttata ctgcccagcc
     1981 ttcattgtat cttctacaaa ggattttata tcatcaatat ttctagcagt tgaaattcca
     2041 ccttgtgcaa gatatgtatt gttgttttca attgttgatt tcgatactac tagcacattt
     2101 aaacttttat ctaaatttaa tgcacagtat aatcctgaaa ctccacttcc aactattaaa
     2161 acatcttgtt ctaaattcat aagtctatcc ctctatcctt ctgctaattt gtgcatgtta
     2221 agcagtgaat ttaaagcctt ttccatgatt tcatcttcta caataacttc attttccata
     2281 tttttaagtg tactatataa attttctaat gttgtctttt tcatatctgt acatagtatt
     2341 tttccaccag gaatataaaa gtttttatta ggattatttt tctttaattc atgtaatata
     2401 ccttcttcag ttgctattat aaagtctttg tttttactat tagtagcata ttttattatt
     2461 cctgatgtac tacctacata atctcctaaa tctcttattt cttttttaca ttctggatgt
     2521 actaatactt ctgcattttt atacttatct tttaactcaa ttatttcttc agctcttata
     2581 ttgttatggt atttacaata tccgtcccaa aatataaagt ttttatctgg aaattgttct
     2641 gcaatatatc ctcctaaatt tttatctgga aggaatataa tttctttatt atctatgttt
     2701 tctagtattt taattgcact agaagatgta acagaaacat cacaatgtgc cttaacttta
     2761 gctgtagagt ttatataaca tacaaccaaa gcatttggat actgttgttt taattttatc
     2821 acgccttctt catctaccat atctgccata gcacacccag cgttacttac tggcatcaat
     2881 acagtttttt caggtgataa tatcttagca ctttctccca taaaccttac tccacaaaat
     2941 acaaccactt cttctttaca atctctagca atctcactta aataatatga gtcaccaact
     3001 gcatctgcta attcttgtat ttctggtggt tgataaaaat gggcaagtat tattgcattt
     3061 ttttctttct ttagctcttt gatttgatat gttaaatctt tatccataat tgcaccgctt
     3121 tctatatgta ctagtgtata tacacctgta aactcattat atcacttgac tattctttct
     3181 tcaagaattt taaacctctt aatattgtta agatatagac atttatattc tcaattgatt
     3241 ttcctttttt ctccatctat ttaaactaat ttttatattt tttaattttt ttgtaaaata
     3301 ttatcagaat tttgtctata ttctttattg ctataacatt gaaaatatta ccaaatacct
     3361 gtatactaag tacatggtta tgtatatgta tttatttctg aaattatatt agttgtaata
     3421 ctttatagaa tttgtaggtt gtccagaatt aaattcaata taaatctaca catttagata
     3481 atatgtatac aaagaccaaa aaattttata aatggggtga tattatgaca acattcttaa
     3541 tcggcttggc tatattacta ataggaggtg ctttatacgg tgcttattgt gaaaaagtat
     3601 ttggcccaga tgacagaaaa acacctgcac ttgctcaaag tgatggagta gactatgtcc
     3661 caatgaaaaa atggaaaaat agtctaattg agttgcttaa tatagctggt acaggaccaa
     3721 ttctaggacc tatccaaggt atattgtttg gtccaatagc attcatacta atacctattg
     3781 gctgtgtatt tggaggagct ttgcatgact atatgagtgg aatgattagt ataagagaaa
     3841 aaggagcaca aatgccttct cttatcagta gatttttagg taataaagta tttcaagtct
     3901 ataatatatt cctttgtctt ttaatgcttt tagttggtgc agtttttatt tatacacctg
     3961 gggatttagt tgttactcaa attttaaata tgaaatcgac tataaataat ccagttgtct
     4021 ggatagttta tggacttatc tttctatatt acttgtgtgc aacactattt ccaattgata
     4081 aaatcatagg aaaggtatat ccaatatttg gagctattct acttttatct gctgctggtg
     4141 ttggaattgg aatctttaca caaggttatg atttagctaa tttaagtctt gcaaattgga
     4201 aaggtattca tcctgatggt attcctctta ttcctacatt ctttgttaca gttgcttgtg
     4261 gtattgtttc tggattccac tcaactcaag ctactcttat agcaagatca gtttcaaatg
     4321 aaaaagaagg aaaaactact ttttataata tgatgatttt agaaggttta attgcaatga
     4381 tttgggctgc agctgctatg ggtatttaca ataaaggaat acctaaggaa ttagtaggtt
     4441 ctcctgatgt aataggtttg gttgcaagag atttacttgg ttctattggt ggtatcatag
     4501 ctataatagg tgtaattgtt ttaccaataa cttctggaga tacagcttta agatctttaa
     4561 gattaatgct tgcagattac tttcattatg accaaaagga aaaaaaacat cgtgttatat
     4621 tgtcaatctg tatatttatt cctgtcatag ccatccttat atttgcaaag cttagtgctt
     4681 ctggatttaa tatattgtgg agatacttct cttggagtaa tcaaactatt gccatatttg
     4741 catttgcaat gattacagtt taccttataa taaaagaaaa gaattatatt ataagcttaa
     4801 ttcctggtat gttttattcc tttgttatat tcagttatat atttaatgct caaattggat
     4861 ttaacttaaa cataaatata tcatatgttt tagctgccat atttactgta ttatatgcta
     4921 ttttaactgt acgctctggt agaaagttaa aaagcaaagc agatactaag ttggctgact
     4981 aaatctaaat aaaataatac ttagaataaa ttttattaaa aaatgataaa aaagtaggca
     5041 atctcaagtt agatttgcct cttttttatt taatacagta ataaatactt aagtatttac
     5101 tccttattgg aatatttatc ctaaatctct aatataaata aataaaagtt ttaaaataat
     5161 ctattcgttt atatacttaa aataaatttt ttggaggaat acttatgaat aataaattac
     5221 atgaacttga aaaaaatcta ccagaaacat cttgttcttt ttgcacacat ctttcattta
     5281 aggggcctag cctagactat agatatgata ttagatgtgt tatttcagat acaaagcccg
     5341 attttagagg atgttgtgaa tattttgaac cagaatatac agaattaaat acaggagatt
     5401 tagacaatct atacataaac tttcttgaga catgcctcaa ggtaaattat aatgattaca
     5461 tcaattctat gtattggaag ttatttaaag aaagaaccct actagaaaac aattttaaat
     5521 gttctatatg tggatcaact gaaaatgttg atgtgtatca tgttaataaa aatttaggaa
     5581 gggaaacttc caaagatgta gttgttaaat gtgataaatg taattgtaaa taagtgtata
     5641 aaatttagat aacttcacat aataagttta aataaaactt aggaggttat ttatgaaaaa
     5701 taataattta aattgtgctg ctactaattg tgcttataat actagtggat attgttatgc
     5761 tggtagtata aaagtagatg gaatgcaagc aactactaca gaaaatactt attgtgcttc
     5821 ttttgaagac aaatatacat ctggtataac tagtcgttct aatgaaacta accaagttga
     5881 tacagataac attcattgtg aagctgtaaa atgtaaatac aataaaaatg aactttgcaa
     5941 agctgaaaaa gttcatataa atgaaagaaa tgcaagttgt gaaacttttg aaatgaaata
     6001 aatttctttt tatttagttt tatagtattt atacaaagca aaattgaacc tatcaaatag
     6061 atgtctttat taatgatgtc tatttatagg ttctttttta aaacaattta taatttatat
     6121 ataaagataa attattattt taatatatta cctagaagta aatttaacac ccagaatatc
     6181 cataaggaac ataaatattg gaactccaat tagtaatccc catacaccta aataatgttc
     6241 tcctacaagt aaaataataa aaacaaaaca aactggaagt ttagttctat tcgacatcaa
     6301 cttagggttt aatatgtatg tttctactgc atgcactata caaatcataa gtaaaactcc
     6361 aaaaaccttt gttattcctc ctgtattaaa tgctattaca gttaatggaa tcaaagacac
     6421 tataactcct gctactggaa taagacccaa cacaaaaatc ataaatccta aagcccatat
     6481 ttgagggaat cccatgaaac ctaagaaaat catagaaaca acagaattta taaaggcaat
     6541 cataacttgt actttcatta cttcaccaaa atttttaaca aagctctttc caaaaaatac
     6601 aagcgaatta taaataaaag aaatcttact atcagaaagt ttatctccaa aatttttaat
     6661 ttcatttttt tcaagtaaaa ggagtaaact cagtaaaaat gccaataata tatttactcc
     6721 aaaacttcca acttttgttg ctgttgatgc tataagtagc cctgcttgtg aaatatattt
     6781 attaaaatcc agctttgaga caataggata caattttggt cctaaagatt gagcaaattg
     6841 atttacatca aaatcactaa aaaccctact caactctgta agttgaacta taattattgg
     6901 tacaactgca tagctaatca atactaacaa tatagcaaat agtgcatata acactataat
     6961 tattaatgaa tctggaatat ttaaagaaga aaacttctta attcgttttc ttgtggctac
     7021 aagcaagtta tagaaaataa aagtcataat aaatgttaaa agcaccatat ttaacatata
     7081 ccaaaatgta attagaataa ttactacgac agatatagaa acaattttat attttgaact
     7141 gtcacgtgcc aatcctttgt tatcttccat agtttaaatc ctccccaaat ttttatgact
     7201 ttataatgac tgcccttttt attttaatct caaaaaacaa gtagaaaaat actaaaaata
     7261 acttattaat tttcataaaa caatattaaa atttagagaa gatacatttt aaataatctt
     7321 acttatactg aaatctgctc tacatcatat atttaattta ttattatcta tctcatatag
     7381 caattcgtat atctctggat attcaaaaaa caaaccctct tttagtaatt gtcttatttc
     7441 atctgtgctt acccacttta tatcacttac ttcttcctcc tgtaaaatag ctttggatat
     7501 atcatattct tttttaacta agtatacatc ccaaagagta tcttcatgaa tcatacttct
     7561 aaaaactttc atctcatctt tagttatatc tatccctatt tcttcctttg cttcgcgaat
     7621 tgctccttct aaactgtctt ccccagaaac aatacatcca gttgtcattc cccacatatt
     7681 tggcaatgtc tttttacttt tagacctttt ctgaattaaa atttgagagt tactatttaa
     7741 aatccacact tcaactgcca aatggtaata accttcttca atagaattac ctctttttat
     7801 aacatttcct gttttaattc catcagcatt atataaatcc cataattcca tttcaaaatc
     7861 tccttgactt tactataaat tagataaact acaaatatat tttagcataa ttaattctgc
     7921 tcatttttta ttacaatact tgatttacat ttatgttcat tgcttttctt ttccttccat
     7981 tctcttatat catctataat aaatctatgt ttcaacaatt ttgtgtcaaa tttaaatatt
     8041 ctaaacacta tttgtaatac atatcctaaa cctaaagcac ttacaagcgt accaatacct
     8101 acagaacctc ctaataacca cccaacaact aatgctagta tttcaagaat tgttctaaca
     8161 agacgtacag atttattagt ttttttctga agagcaatca taagcccatc tctcggtcca
     8221 cttcctaaac aaacacctaa gtatagaaaa cttgctatag ctgccaaaat aattcctata
     8281 acaaccataa acacacctat ataagtgttg cttgcatgag gtatcactcc agaaaatatt
     8341 actaaatcaa taaaaattcc tataaatgtc atgttgagta aagtacccca tcctatattt
     8401 tcaccaaaaa ctgcatccaa tataacaatt acaactccta ccattataga agcctgacct
     8461 atagttatgc ctagctttat agataaacct tggtgaagta catcccaagg cataagacct
     8521 acatgtgcat taatcataag cacagaagaa attgcaaata taaaaaaacc tgaaaataat
     8581 cttatcatac tttttaaact tatttttccc atcaaaaatc actcctcata ataataataa
     8641 caataaatac caataaaata tatatataaa tacgaaattt tacagaatta tttattaggt
     8701 taagataaaa ttttaattat aaaaagtggc aatccaaatt ttatacattt tcacctatac
     8761 tctaagcttt cgtgtataaa aaacggatat accacttttt tagtatataa acatttttag
     8821 tttttcttat taattttcac tataaattct agcttcttct tctccattta gtactcttaa
     8881 agttccaaaa gcaagtgatt ccaactcatt ttctcctgcc ataatttcta ctggtgctat
     8941 aaactcaact ttctttttaa ccattgaagt aaacatttca gaatatgcaa ttccacctgt
     9001 tataattata gcatctacct ttccatctac tacagttgct aactctccaa taccttttgc
     9061 taactgataa gccattgctt cataaataat ttttgcttct tcatttcctt ctgctatcat
     9121 tttttcaact tctctagcat ctacagtatt taggtatgaa actataccac ctttacctct
     9181 tatcttttta gtcatttctc tttctgaata ttgacctgaa taacaggcag ccactaattt
     9241 tgtagcaggt actcttcctg acctttctgg agaaaatggt ccttcatcat cagatagcat
     9301 atcaaccatt cttccttttt catgaagata aatacttact cctccaccaa tgtgagctac
     9361 tattaagttt aagctcttat aatcttttcc tttatcctta gcatatttta aagccattgc
     9421 tctagtattt aatgcatgcc ctgcacttga tctatccatt ccacaaagtc cagatattct
     9481 cgctacatct ataagctcat ctactgcaac agaatcataa atatatgagt tgattccaag
     9541 aggttctgat attgcatgtg ccacaacagc acctaaattg gaagcgtgtt caagtactgg
     9601 tctatgtctt agtacatcaa tcatttcttc atttactaaa tatgctcctg attttactgg
     9661 tggtaaaact ccacctcttc ctactattgc actaagagat tttaagtcta tactattttc
     9721 tttaagaata ttcaaaactg cttccttacg catttcaaac tggtcttgta tagtattata
     9781 ttttgcaatc tcttcagctg gatggtctat cgtcttcaca agaatttgtt cttctccatc
     9841 atatactgct atttttgtag aagtagaacc tggatttatg gctaatattc tgtaagtcat
     9901 aattttcttc ctttcacctt aatttctata gtctatttat atctattata aactatttgc
     9961 taaccatttc cataccttca tggaaagctt ttatgtttaa ttcaacaaat tttggtttaa
    10021 cattttcact tataattttt tcccaatcaa tagactctaa ttgcatagat ttaactagac
    10081 atcctaataa aataacattc attatttttg aatttcctag ttcttcagct ttatcagctg
    10141 catttataac ttttgcattt aatctactta actctgcatc tatatcactt tcttgatatt
    10201 cagctcctcc gattaaaaca gtcatagaat ctatcctatg attattcact aaagcttttc
    10261 cttctggttt taaataattg aaccatctta aagcttccat tttttcaaaa gatactaata
    10321 tatctgctcc accaatttct ataactggag aatgaacaca atctccatat ctaacttgtg
    10381 aggaaactga acctcctctt tgactcattc catgtatttc actcatcttt acatcatatc
    10441 cagcttccat caatcccata gttaataatt tactagcaag tatagttcct tgacctccta
    10501 cacctaccaa aagtatactc ttagtcatat tatttttcct ccttaactat tgcttgtttt
    10561 ggacaaactt gtgcacatac tccacatcct acacactgat ttctatctat atttgataac
    10621 ttattctctt tatcaaatga tagagctgga catccagttt tcaaacataa tttacatcct
    10681 atacatttat catggtcaac tttacactta gtcttaaatg gattattaaa ttcttctata
    10741 tcttctttag agaatttttt aagtacacat ggccatcttg ttattattac tgatggttca
    10801 tcttctatag ctaaagccca atctagtgct tcatttactt cttttaaatt attagggttt
    10861 ataactctta catgttctat tccacaagct ttaactaatc cttctatatc aacttcttta
    10921 gttttagcac cttgtaaagt atatcctgaa cctgggtttt cttggtgacc tgtcattcca
    10981 gttattctat tatctaatat aaccgaaata gaattacctc tattgtaaac aacatctaaa
    11041 agtccattta ttcctgtatg gaagaatgtt gagtctccaa gtacacctac caatcttttt
    11101 tcattatcat ccttcatatt aagaactttt tgagctccat gtgcagttcc aaaagcagaa
    11161 cccatacaaa caacataatc tattccatta tatggaggag caaatccaag agtataacaa
    11221 cctatatctc caccaactat taaatttttt ctctttccaa gttcatagaa gaatcctcta
    11281 tgtggacatc ctgcacagaa acttggtggt cttggtgtta ctaattcaga tttgtattct
    11341 atagtatcat ttgtttttcc aaatatagct tttcttaaaa catctggtgt catttctcca
    11401 tatggtggta ttacatcttt tccaatacaa tctattccat atgcttttat ttgttcttct
    11461 ataaatgggt cattttcttc tataacatat attttatcaa ctttttctgc aaattctttt
    11521 attttttcat aaggtaatgg atttgtaaat cctagtttca tatatgatgc attttttcca
    11581 aaaacttctt tggcaaaatt acaacacata ccagatgcta taacacctat ttttgtatca
    11641 tttatttcat agtagtttaa atcagtttca tttgagaatt ttttaagaat ttccattctt
    11701 tcttcaacaa cgccccttct tatttgagca tttgctggaa cagttaccat tttcttagca
    11761 tttttaacat actctttaat ttcaacttct tctctatcat agcactccac taatcctttt
    11821 gaatgacaaa gtcttgttgt aactctatat aaaactggtg tatcgtattt ttcactaact
    11881 tcaaaagctt cttttatcat atctttagct tcttgactag ttgatggttc aaataaaggt
    11941 atctttgcaa attttgcata catcctattg tcttgctcat tttgagatga atgcattccc
    12001 ggctcatctg ctgtaataag taccatacca ccatttaccc ctgtatatgc ataagtaaat
    12061 attggatcag ctgcaacatt caaaccaaca tgtttcatag aagccattgt tcttgctcct
    12121 gcaattgaac cccctatagc agcctcaagt gctacctttt cgtttggagc ccactctgca
    12181 actattgcat ctttatatgt tgctatattt tctaatattt ctgtacttgg agtccctgga
    12241 tatgcagatg catatttaac accagcctca taggctccac gtgcaattgc ttcattacct
    12301 gtcatcaatt gtttcatata aaattccctc catctacaat tattaaattc atagtccacc
    12361 caatttgttc aatgaaatta attatttatt tttacttcta aactttcaag tgcttctttt
    12421 ataatacttg gtgctttctt acatttatct tcagaaactg cacaaactgc aaatcttaag
    12481 cccattttta atggaactgc aaataaatta tgtttagtca attcttcaca tacttctttt
    12541 ggattatcac atggtatact tacaaagaaa cctgctatat atggaagaat ttctaatcct
    12601 actctttcag cttcttttac aaatacatct gctcttctag taagcatgtt tttgtatatt
    12661 tctttttcat cctcatattc tttgaatttt ttagggtcat ttacaatgtt agataatact
    12721 gccatagcac ttctattaca atttgaccaa tttgctctac atgaatgaac acatgagtaa
    12781 tggaactctt cagctacatc ttcacttgaa gatatacaaa ttatagctcc cattctcata
    12841 ccataagctg taaatccttt tgacatactg aatccaacca atacgagaac gttttcaggc
    12901 aaattagaaa atttcttaaa aaactttcta catacatcat catcacctgc aaagtcaata
    12961 tatgctgaat ctacgaaaaa tattatcttt ttgtctttat cttttgcgac ttcttttgat
    13021 aagtctaata ttttatccca ctcatcatct gcaacactat atccagttgg attatgcgct
    13081 ggtgtgttta taattgtaaa gactctacct tgtttttctg ctatatttac aaatttttct
    13141 ttaaacgact caaaattaaa ccttctattt tcatcaaaaa gttggtaatt aactactttt
    13201 ctattagcct cttcagctat acttacatat ggactccaga accaatcaga tgttaatacc
    13261 tcatctcctt cattagtata gttccataca gctaatttta ttgcaccact tcctcctggt
    13321 gaagctaata ctcttatatg tccttctggt aagtaatctc tgaaaaatac ttttttaact
    13381 gcttctaagt aatctggttg accttcaaga gctgcatatg cacctatctc acagttatct
    13441 aatgctttat attcttcata tacagttttc attgttatca attttcctga atcatccatt
    13501 agagcgccta ttgttgcatt tattacatta tccataccaa aagccttctc tgctgcttga
    13561 gctctgccag atatgctaaa tataacatca ttttcttttg gccacattgc atgcttacca
    13621 accatacttt gactcatacc atcaccccta aaattgtatt tactcttaca ttatatatta
    13681 agcaattact atgccaataa atcccacttt atgtaaaatt gattttgttt agaattatta
    13741 tttttttcat tattaaatta agtgttttaa ctatttttct tataaatata tatgcctgtc
    13801 taaaaaaata aaaatttgca aaaaagtaat gttaattttt cttaacactt gttttaaaaa
    13861 attaacatta cttcaaaata atttatatgt aattatattt aaatattttt attgtatttc
    13921 ttccataaag atgtcctgct tattccaaga acttgtgcaa cttcattttt agaaagtccc
    13981 tgagcaaaaa gcatacttat tattttttct tcaacatact tatttacttc ttttatatct
    14041 atacttatct taccatcatt tatcttactt atatttatag attcatcttg gacttctaca
    14101 cttgctgtcg tttcagaatt aaatttgtct acttcagagt taggaagtaa ttttttagtt
    14161 ttaaaatctc tatcttgtct caatttaatt ttacctgtca caacatattt ttgagctatt
    14221 gtctttaact ctcttacatt tccaggccag ctataattat atagcttatc catttcatct
    14281 ttagtcaaaa caaaattttc atctatactg tttattccat tgagaccatc atcctttaat
    14341 acttcattta caaaattgtt aaacaaaggt attatatctt ctcttctgtc tcttaaagga
    14401 ggtatattta tctctaaact actcaatcta taaaataagt ctgctctaaa tgtacccata
    14461 actatttttt cggttaaaga ttcattcgtt gctgctataa tccttatatc cagaggtatt
    14521 atataatcag aaccaattct cattatttga cgttcttcta ttactcttaa tagttttgtt
    14581 tgaatattaa aggatagact atttatttca tctaaaaaaa gagtccctcc atgagcaagt
    14641 tcaaatagtc ctctttttcc accctttcta gcaccagtaa atgcaccttc ttcatagcca
    14701 aaaagttcac tttcaagtaa attttctgct atagtagcac aatttatagc aacaaaaggc
    14761 ctatcttttc ttttacttat gttgtgtata ctatgagcta taatttcttt accagaccca
    14821 ctttctccat aaagtaaagt tgtataatca ctttttccaa tttttttagc ttcttcaata
    14881 aattctttag ttaatttatc tttaaataaa aaatcatcaa aagtatatct agcatagaga
    14941 cctttttgat tcaagtcaaa tcttattttt ctttctaagt tttgtagctt ggttatatct
    15001 tgtattattc ctaaaactcc ataagtacta ttatcaactt ttatcaatgt tgtcctagta
    15061 ttaacaatta gattatttat atttcttatc tttctatctt ctacgtcctc tttttcatgt
    15121 aaacaatcta acatccactc cattttagga aatacatcta agatgtattt attaagtgca
    15181 cattttctct ctactttaag catgtttttt gcactttcat tgtacaaaat tatactgcca
    15241 ttactatcta tagcaattac tccatctttt ataccatcaa gtatatttcg taacacttca
    15301 ttattaaact tttcttcacc taatgtatct aataattttt tacaatattc tacagcttct
    15361 cttatagatt catcactagc agttgcaaat acactatcaa ttccatattg ccttgcaaaa
    15421 gaacatgcca aacctcctcc tacgattaca acttcatctt tttggtctat atattttaca
    15481 actttacttc ttatctcata cttagattca aaccattctt cagttatttc agtacttatg
    15541 acatttctcc agccaacata gtcaaaagaa acttcattgt ctccaagaat caatactact
    15601 tttttagaat atttctttgc tatttctatt gctcttaaaa ggtcagttga cttcatattc
    15661 attggtataa caggtacatt tactgtatct attactaagc tataacctcc acctctacca
    15721 attatagctt gggcaccttt ttcaacaagt atacgacctt gattttccat taagtctagg
    15781 ttaagtatgt cgattattat agttccattt tctacatctt ctctatataa ttcttctatt
    15841 ctttctttta attcaatatc agaggctata attcctattt tttttcgcaa caaaatcacc
    15901 tcaattttaa attataatgt attgatttct acctgctttt tttgatttat ataggttctt
    15961 atctgcatct tcaattaata tttcaacatc ttttctacta cgacaccttt ttatacttac
    16021 tccagcactt atagttatat agttttttat tttagaatat atatgttcaa taccctcaaa
    16081 ttcaagaagt ttgaaaactc ttttaatata taattctata ttatcaatct cttcaacacc
    16141 gattgattct atagaatcta ctaatattaa aatttcttct cccccatatc tgattatgtg
    16201 ttcggtaata tctataaata cacttcttat aatatcagtt accttaacta taactttatc
    16261 ccctgctaga tgaccataat tatcattata acttttaaaa caatctatat cgaccagtat
    16321 tgcgaccata tttttgtctc tggttccatt aaataaatcc aactgctgtt ccaaatatct
    16381 tctattatat agtttagtaa gtccatcttt taaaatatca ttttctaatt tcttattatc
    16441 atccactagt aatcttaaac tctcttgttt ttgtctgagt tcatattgtt tgtgaattgc
    16501 ttgagatgtt ttataggaat tatttttttc ccacctatca gaataccaat ccatactttt
    16561 ataatattct attgccagtt taaaatcttt ttttagctca tatccatttg ctattagccc
    16621 atataaatat agatattttt ctaagattca atgaactctt tttaactaaa tttaaacctt
    16681 ttatataaca acttatacct tcatctatat taccaaattt tatatataaa tctccataca
    16741 acttatatat gtaatctagt ttagaattat atataaaaac atctccaaaa cttttatata
    16801 tattttttga taaaattaaa taggtgttta ccttttcaaa actacaatta tctttcttta
    16861 actcaatttc agctgaatat aaaaatataa atgaatataa ataatcctta tatacacctt
    16921 caacaacttt cattaatttt atagtcttta ataaaataac ttctgcttct ttattcatat
    16981 cttcttttaa atatgcccat ataaggtcta tttttataga cactctttca gttactgata
    17041 ttgagttatt actgtgtgca acatctaata cattatttat gtattttata gcttctacat
    17101 tatttccact ctctaaataa cacaaactta ttatacattt acaaaaagcc tctatagagt
    17161 ataaattatt ttcttgagcc aattttagac attcaattaa gtattccata ctttttataa
    17221 agttattaaa taaatataga taaactctcc caaatatata atttgcccta cttacaagag
    17281 ctttattttt taaagtttta aaaaaagaca cttcttctac taaagctatt acatccgttt
    17341 tggtctgata taaagcactt atttccacac ataaactcat atttaacaat accaacaact
    17401 catttaaatg attttgcctt ataatttttt ttgctgagaa ataaaaatta tttaccttat
    17461 catattttct tatagaaata gctgataaag taagataaat ataaatttta gatattatat
    17521 ctgaatcatc ttttaatgac aattttttaa tatactttaa tgactctatc aaatagttgt
    17581 atgatgcttc tctatctttt tttatatagt ttataagact aattaaatat aaagtataga
    17641 ctctactatt atcttctaat tttgtattta aaaggtcttt gtgataatcc aagatgtagt
    17701 ttaaatctgt caaatttaga tagaatttag tcaacatatc gtattctatc ttgtttatat
    17761 ttctctttaa atcttctatt aaactccttt tcaagtaaat caccaatcct atttcaacag
    17821 ttaaaaattc ttaaaatcat gataatgcaa acatctattt ctaccacttt cctttgcttt
    17881 atataaagct ttatcagcat tttcaattat ttcttttata tctatactac tatttttaca
    17941 tgtatcaatg ccaatactaa ctgtcaaatt attatttaaa aatttcttta caatcctaca
    18001 taattttctt ccaaatattt tacttttttt ataatcttta catacagata atatcagaaa
    18061 ttcttctcca ccatacctta tcataagcat gtcttttttt agatattttt ttattattat
    18121 agttatattt ttaagagcaa tatctccatt ataatgtcca taagtatcat tgtattcttt
    18181 aaagtaatct acatctatca taaatgctgt gcaatattca ctaacttctt gtttttctaa
    18241 aaaatcgttc aaaaaagttc tattatatgc acttgtcaaa tggtcaacat actttttttt
    18301 atctaaatca agttttactt ttctcatgtt atttatttct ttttctatat actcatgtct
    18361 ataatttaag gaatctatat aatttctatt tcgagctttt atatacatca tttttaactc
    18421 ataatacatt ttaaagtatt tcatactcat ttcataattt tgaatctttt caaaacacaa
    18481 atatatactc ttgtatgcta acttcacata attataattt ttagcatttt tagatttttc
    18541 aaggagtttt ttatttgtat ttaaggcatt gtcataatat ccaaagatat aatatatctt
    18601 tgcctggtga taaattattt ctaaatcata tattatatat tcttctatat tttttatcat
    18661 atttaatatg tttttagctc tatctaaata gcatattgat tgttcaaaag atttttcatt
    18721 actttttgca taatacatgg ctaaacttat aaataaatca aacttctcta cttcttttaa
    18781 gctatgattt ttaatttttt ctagatatac ttcagatttt gctaaattat ttattgcgac
    18841 aggataattt ctagtcttta ttaatatttt agttatgttg tttgatgctc tatatttttg
    18901 aattatattt acatttctat actttttatt gcttattact tcattgaaat attccatgga
    18961 acattcataa ttttcaaacg aacattcaca ctcacctatc tttatattac atagtgaaga
    19021 tacttgcata tcctttagta aatctgcata ttttcttgct tttaaaaaat ttaccttagc
    19081 aattagagca tcatccaaaa acaaaaaata tattttacca ataataaaaa aatatatttt
    19141 tttacaatta aaatcgttaa tttcttttat ctttatatac aacgtttcta tttctttaat
    19201 tattacagaa gattctatac acttacttgc cttaatgtaa ataagttgtg atttaaaaat
    19261 aatttcttca attagaaaat tattttcatc acaaataaga ttaaatttat ccatatataa
    19321 atttgcctta tttacatctt cattttttaa acttaaaata gctatttgtg aataaaatcg
    19381 tgctaaaaat ttataatctt tgggtaagca tttatcaata tatttacagg aaatcaaaat
    19441 atactctttc attttttcac taaacccttg aataccatat aataaagcta gcaaaaaatt
    19501 tgattttaat aacattaaac tattttgttc agttttatag caatcaatta aattctttac
    19561 tacatcaatt ttattttcaa taaaatcgtt attagtcaat aatctttcat tcaaggttag
    19621 tttaaacatt gaatctaaaa ttgtatcatc tatctcttcc aaatatttac tatatattgt
    19681 aactcacctc cgacttacat tatctcataa atttagtaat tttccatact atttttgaaa
    19741 aaagttgatg tctcaattta gaaatttctc ttaaattaag acatacttta cactaaacta
    19801 tacaattttc tatctgaact atataatcct gacaattttc gcaaattatc acacttacaa
    19861 tataactatt atcaacttta tttgcccttg atagtttatt aaaagatagt cctttataat
    19921 caacagatat attgcttatt acatattctc catctttact gaaaatataa aagtgatatt
    19981 ctaaaaaagg aaagaatttt ttcttttctt ttactccttc taaacataat ggacatgctt
    20041 cttgataata ttctacatca aaatcaactt cttctgcttc attaagtata tcaattattt
    20101 ttgaaatact tactccttga actggatttt cttcatcatt tattaaagca ctacagttct
    20161 cctcttttaa taaatattcc ttatcatcat atataaactt atataaactc atattatatc
    20221 ctccttataa ttattaatct ccaagttatt ctaccattta aataaagtta ataaaagtaa
    20281 ttgtttataa tctttataat taagttatgt atacatatat tcctatgcgc tatcttaatt
    20341 aatgatttta aaatccaagt ttgcactttg aacatccagt ttcccaaaat ctattgtcaa
    20401 aactcacttt agttattaat ataatgatat aaatatataa ctgcatagat gttacacact
    20461 taactattta atatgatacg atttggtatc taaatttata tattgtatat agggggagat
    20521 atatatgtat aaagataaaa gtgatgaatg tatacactta atgactgcat acatcgatag
    20581 tataagtgga tattattcat ttattgacac acaattagag gattttatga tgaaatatgg
    20641 tgaaaacatt gttgattcaa atttacacag tataatgatg ttgctttgta aatggggatt
    20701 atcttagcat ttcaagaaac ttttttgtat attgtattct atattattta ttcattaaca
    20761 aaaaagattg acataaactt aaaagctata tatagatttc tttaaaaatc tatatatagc
    20821 ttttttaatt ttttcaaaat gtatacttaa ataagttagt ttttttcaaa atttgactat
    20881 ctaatatgat ataatttaac tatctacaac aataaaaaat atctaatatg tattatctag
    20941 tttagctcat cataataaca tccctatatt tacaattaag atattttcaa tatagtaata
    21001 ctcaatttta atattataaa aaggagagat tttgtatgga ttacaatgac ttactaaaat
    21061 cagctagaga gaactttaat ggaacatgta aagtatgtaa aatttgtaat ggattagctt
    21121 gtgctggaga tgttcctggt atgggtggta aaggaagtgg ttcgtctttc attgaaaata
    21181 gaaaaagtct agaaaaaata aagataaata tgagagtcat acataatgtt tcaaagccag
    21241 atacatccat agaattattt ggtagaaaaa tgagttctcc tatattcgct gcacctgtat
    21301 caggtactat attgaacatg ggtggtaaag tttccgaaaa agaatacata gagcctgttg
    21361 ttagaggttg ttctaattct ggaatttatg ctatggttgg cgatactaat gtagatactt
    21421 ttttactgga taatttagat gtattgaagg ataatagggg aaatggaatt gtatttataa
    21481 agccttggaa taattcaaag ataatagata aaattagatt gtctgaagaa gcaggtgctt
    21541 ttgcagttgg tgtagacctt gatgcttgtg gacttattaa taatcaattt caagaaaatc
    21601 ctttttctcc taaaacaatt gatgagatta gagaattggt tgaatccact agattacctt
    21661 ttattataaa aggaattatg actgtagatg atgctttgat ggctgtagag tctggtgcta
    21721 gtgccattat tgtttcaaat catggtggaa gagtacttga ttatactcct ggtacttgtg
    21781 aggtacttcc agatatagct aagtctgtaa agggaaagat aacaatactt gttgatggtg
    21841 gagttaggac tggtgttgat gtagttaaga tgcttggatt gggtgctgat gctgttttga
    21901 tgggaagacc ttttgttact gcttcttttg gcggtggtct tgatggtgtg gagtttttta
    21961 tagagaaggt taggaatgag ttatgtgaga ctatgatttt gactggttgt caaaatgtta
    22021 aggatataga tggtagagtt atatggaatt tattgtaaaa tagttttata acatttatat
    22081 ttaaatagtg tctcatttaa attgaaaaat catattgaga cactatttaa tatattttta
    22141 gattttaatc ctatgaaaga gtagggtcag ttagtctacc caatttatcc caagtagctg
    22201 gaccaattat tccatctgca gacaaaccgt attttttttg gaaacttaca actgcattat
    22261 atgtcttact tccaaaagaa ctatctatac ctacattata accaagtaaa gttaacatga
    22321 tttgtgcagc ttttacttct tttccgctat taccctttcg tataactttt gttgtactta
    22381 tagtcaaata ctcattactc ataattgtta tagttttagc acctatatta taagaaacag
    22441 tataacttgc ataaacacct ttactattgt cctcattcat tagattagct gattctggaa
    22501 caaatatctc atcatctggc ttagggtcta tatttatctc ttcacaattt tgtttatgtt
    22561 catctcttat ttcttgtggc gcattttcat atgtatatat atacccagaa agagtaaaag
    22621 aatctaggtt tttctctgga acagtctctt tacttcctcc tttctcttta cttgtgtcag
    22681 caaatgccac acttgtaaaa gtaagcaata agcaacacat aatagctact atttttctta
    22741 attttgttaa cataaaatcc tccttataat tattttatta attgattata atctttcata
    22801 tccatttcta ttatgtcata gtctctaggt attttacctt ctaattcgca tttatcttca
    22861 taaaatttcc taatttcatt tggtgcatct ttataataaa tatttataat tttatcagtc
    22921 gtcttattca ataaaaattc attaatattg ttattcattc cattattacc ctcatcaatt
    22981 ctaacttgag catcaacttc aacaaaagat gttatagaag tcataaatac taaaacagca
    23041 attagtattc cacttttgcc tttcttttta acaatactct caagtctctt ttccaaattt
    23101 gtcttatcaa actcggttgt caaaatctta ctattataat ttttactaaa cttaattgac
    23161 tttataagtg ctagtgcata ttctttttta tcttttaaag aacattctac caaaacactt
    23221 tcatcacaac ataattcaca atctagattt actttattgc tcattacata tacaagtgga
    23281 ttaaaccaat atattattct aacagacaaa actaaaaact ttattaaaat atctttattt
    23341 ttaaaatgca ttaattcatg tttcaaaatc caagttagtt catctttact ataaggatag
    23401 tctggtaaga atatgtaaga tttaaataat cccatacctg ctggacttat caattcatca
    23461 gaacctctta attcaatttt cttttttata tttaattctt ttaacaagtt tttgtagata
    23521 cagtttatat cattatcttc aatatcataa gatacatcaa caactagatt tttaaatctt
    23581 gtatacttta taaatgtata aactgcaatg actatagtta caaataacca taaataagct
    23641 acatacagca taagattatt atctgtagaa atatcaattt gtgtaatatt atttcctaat
    23701 gcattttctt tgggttcttt tacttcatac actattgtat aattaaatag aaaaagtaac
    23761 attctaaaga ctattatcaa ccaaatataa taattgaatc tcttactaaa cttcttaaat
    23821 aaatatcttt tcaaaaataa taatagacaa ataccaagac tacatacaat agttgtcttt
    23881 ataagatttt caaaaacata tagcatataa ttattcatcc tttaaattat caaaataact
    23941 ttctagaaaa tctagcttat ctttacctat attttcatca tcatgtaatg ctgaaattaa
    24001 gcttcttaaa gagtcatcat gtatattact taggaaatcc tttgtctcaa aacttaaata
    24061 atctttgtgt tttactctta ttgtgtaatg tgtatatctg tctatttttt gagcatctaa
    24121 gaatcctctt tttaccagcc tagataaaag tgtcagtgtg gtggtttgtt tccagccata
    24181 tttttgttcc atagcttcaa taacatcttt tgatgtcact gtaacatcta ctttccaaat
    24241 gaatttcatt acttttagtt ctgcttgtgg tatttttctt atcattattt acacctccct
    24301 caaaactcct gctaccttaa ttctacaaca tgtgaatttt ttagtcaaac actttatgaa
    24361 aaaaatgtga atttttgtac tttttgttaa atttctaatt tttttacaat attaaaagtt
    24421 agattttaaa atatatctat ttaaatattt tactttttac atatttaatt acaatagtgt
    24481 agaatgttat ttacacatta aaactattta ataaaaattc ctatattttc acacaaggaa
    24541 tattataata ctttttttta aaataaacta gagtaatatc taataaattt taataacatt
    24601 ctaattatg
//
LOCUS       DAYAOO010000060        24543 bp    DNA     linear   BCT 12-OCT-2024
DEFINITION  TPA_asm: Clostridioides difficile isolate ST8-SSI-h139-18
            SAMN40601845-rid21577343.denovo.060, whole genome shotgun sequence.
ACCESSION   DAYAOO010000060 DAYAOO010000000
VERSION     DAYAOO010000060.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN40601845
            Sequence Read Archive: SRR28438827
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 24543)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 24543)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-MAY-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-MAY-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002157583.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002157583.1
            Genome Coverage       :: 163x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/11/2024 16:19:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 4,038
            CDSs (total)                      :: 3,963
            Genes (coding)                    :: 3,930
            CDSs (with protein)               :: 3,930
            Genes (RNA)                       :: 75
            rRNAs                             :: 6, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 60
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 33
            CDSs (without protein)            :: 33
            Pseudo Genes (ambiguous residues) :: 0 of 33
            Pseudo Genes (frameshifted)       :: 7 of 33
            Pseudo Genes (incomplete)         :: 25 of 33
            Pseudo Genes (internal stop)      :: 11 of 33
            Pseudo Genes (multiple problems)  :: 8 of 33
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..24543
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN40601845-rid21577343.denovo.060"
                     /isolate="ST8-SSI-h139-18"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Denmark"
                     /collection_date="2018"
                     /collected_by="Statens Serum Institute"
     gene            175..1503
                     /locus_tag="ACGI5H_002596"
     CDS             175..1503
                     /locus_tag="ACGI5H_002596"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896511.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="APC family permease"
                     /protein_id="HFG9698294.1"
                     /translation="MGSNELKKTLGVSAALSTVVGSVIGAGVFFKPQAVYTLTGGAPG
                     LGILAWLIAGIITITAGLTAAEVSVAIPKTGGMMVYIKEIYGEKLGFLTGWMQIVLFY
                     PGMMAALGVIFGEQASALIGSPSLLLPIAIGIIIIVAGLNMLGSKTGGVIQTVSTICK
                     LIPLILIMVVGFIKGGGNNPILTPMVGEGLSLGSVLGQVLIAILFAFDGWMNVGTLAG
                     EMKNPGKDLPKAIIGGLSVVMAVYFIINLAYLWVLPANELANYASPASAVAEVIFGSM
                     GGKIISVGILISVFGALNGFLLTGSRVAYTLATDKTLPKYGIFSKLNSAQVPANAIAL
                     VSVIASIYALSGQFNLLTDLAVFATWIFYVLTFIGVMKLRKTHPNIPREYKVPLYPIV
                     PIIAIASGIFVVVNQLCFAGMKTTMISIGGLVITAIGLPVYAYMTRGVKR"
     gene            2256..3089
                     /locus_tag="ACGI5H_002597"
     CDS             2256..3089
                     /locus_tag="ACGI5H_002597"
                     /EC_number="3.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902571.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016810 - hydrolase activity, acting on
                     carbon-nitrogen (but not peptide) bonds [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide deacetylase family protein"
                     /protein_id="HFG9698295.1"
                     /translation="MRNKKKKINRKKLYLLLSAIVVCLAFIVVGVRVSSLNMKENEIS
                     RNAKLSSSTITDIVSNTSIEVSKGPSKSSGKIAYITIDDGPSKFTDQMIKTLNKYNVK
                     ATFFMIDGNMKEYPQQVKNIIKNGNTAGFHSVSHDIHKLYVTSTSAKEEFDTNDQTFY
                     KITGKHSKVIRIPYGSKPYTPQASYQALVDAGYKIWDWDLDTEDWRSNSSQIVQNVKN
                     HIKNRKGEDKDQLVVLMHEKKQSAEALDSVLKFLSDEGYEFAPVDQNQIPKNYWLRNL
                     E"
     gene            3158..4114
                     /locus_tag="ACGI5H_002598"
     CDS             3158..4114
                     /locus_tag="ACGI5H_002598"
                     /EC_number="5.2.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728548.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase"
                     /protein_id="HFG9698296.1"
                     /translation="MNKKLYIGMVGILSLMMVGCNKSLAKVNDVEITKEQYKKTKAVL
                     SATNNYINGQSLDELEKTLDKKGRNKLENVIISFMVDNELLYQEAKDKGLTPSKSEVD
                     SKYQELEDKMNLNTSYKEKMDKAGVDKDYLKQEISRDLAIDKNKKAFEDRINISDNDM
                     EAYYTSHKKDFNVEEVSASQILISTLDKNKKEVSKDKKEALKKKADNILTKIKNGESF
                     ESLAKKYSDDKATGKNGGQLGYFTKDDKNAEFTKEVFKLKKNEVSNVFETSYGYHIVK
                     VTDKRERQKSFNECQSLIRESILNEKYIEHIKKLNEDAKIDR"
     gene            4166..4648
                     /locus_tag="ACGI5H_002599"
     CDS             4166..4648
                     /locus_tag="ACGI5H_002599"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436663.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_function: GO:0016987 - sigma factor activity [Evidence
                     IEA];
                     GO_process: GO:0006352 - DNA-templated transcription
                     initiation [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-70 family RNA polymerase sigma factor"
                     /protein_id="HFG9698297.1"
                     /translation="MFKSLKRTKVEKYIIDNKDSFYRIAYSYTKNEEDALDVVQEAMY
                     KALYSVENIKEVNYIKTWFYKILVRTSIDFIRKNRKYNNMTDIDLIDETGEYDKYTDL
                     DLRRALEELPIEYKSIIILRFFEDLKIEEVAIILDENVNTVKTRLYTALKKLKLKIEE
                     "
     gene            4660..5529
                     /locus_tag="ACGI5H_002600"
     CDS             4660..5529
                     /locus_tag="ACGI5H_002600"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728549.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3298 domain-containing protein"
                     /protein_id="HFG9698298.1"
                     /translation="MTSKERLNKLKDEYHKIPIPKKLDTIINHEKIENIYREKNKKVN
                     RLRFKVAIAFACIFTVLVNISPVFADNFSKIPVIGAIVEVITIKNYSLKSENYEAEID
                     IPKIRGLKDKNLEQRLNSSFMEDGKRLYHQFQERMEKIQSSKNKGYKSLSLSYSVKNN
                     SKKFLSIEMTKNEIEASSYVSKVHYTIDKKRQIVLTLPMLFKDDKYIKVISDNIKEQM
                     REQMKKDSTKSYFIDQKKDLPVEDFKTINKYQDFYFNKNEDLVICFDEYEVAPGYMGA
                     VEFVIPYKVIKDL"
     gene            5572..6327
                     /locus_tag="ACGI5H_002601"
     CDS             5572..6327
                     /locus_tag="ACGI5H_002601"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861251.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3298 domain-containing protein"
                     /protein_id="HFG9698299.1"
                     /translation="MTTYKKLKKSIFKIAIFSICLLASLVDTNPIFAGSSFNETSNSD
                     TIKVLNAKSINFKQDNYEVNVSIPKIKGLKDKTLENKLNNEFLQDGKKIYSEFQNKMK
                     KEDNKGHRYLNVIHNVKNNSKDFLSIEMTKEEIEASSSITKKHYTVDKNRGILLNLPI
                     FFKDSRYIRAISDNIKEQMRNQIKKDDTKSYFIDQDKDSPVKDFESINKYQDFYFNKN
                     GNLVISFDEYEVAPGYMGAVEFVIPNKVIKRLR"
     gene            6369..7190
                     /locus_tag="ACGI5H_002602"
     CDS             6369..7190
                     /locus_tag="ACGI5H_002602"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889422.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="XdhC family protein"
                     /protein_id="HFG9698300.1"
                     /translation="MNIYEQAIRLIENNEDFAFATITSHSGSTPRETGAMMIVKNDST
                     IFGSVGGGSVEAECIKHAINVIKNRESMLYKFTLNKSDVAKLGMICGGTGEIQIDFID
                     SKLKSNIEKFNKRLKENTSKAYIFGAGHISRDVAVILSLLEFRTVVIDDREEFANHER
                     FPESEVVVLDSFENIPDFPTDENSYIIILTRGHLYDSSALEWALKREAGYIGMIGSRT
                     KIGLTYEKLMKKGFKKEELSKVHAPIGIKLNAQTPAEIAVCIAAELINCRANKEK"
     gene            7195..7956
                     /locus_tag="ACGI5H_002603"
     CDS             7195..7956
                     /locus_tag="ACGI5H_002603"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429799.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="M48 family metallopeptidase"
                     /protein_id="HFG9698301.1"
                     /translation="MNTGSKDIDTLKVNFRGIEIKAVLVYKNRKNISIKIDPFGKITV
                     MSPPKISKKIIKDIIIEKGDWILKKSEKCKGREEVYKQRMFITGEKFLYLGEEYHLVI
                     KELLRDSVKKSNCRITINEYQIVVQTNDTSTDFIKKSLKSWYKMESERIVLERIDFLK
                     LNCEIMKQLVPASVKVKEQNKRWGSCTAQKNIYINSKISMARLDVIDYVIIHEFSHLV
                     HMNHSKKFYDLVKSIMPDYKDKENWLKINGYKIII"
     misc_binding    8117..8374
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            8487..8726
                     /locus_tag="ACGI5H_002604"
     CDS             8487..8726
                     /locus_tag="ACGI5H_002604"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429800.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ACT domain-containing protein"
                     /protein_id="HFG9698302.1"
                     /translation="MENTVYAKLNQGIDSFLRVAMTLRRREVDIQSISMTVDNMNNSG
                     IKLIVNEEKTSLDSVLNHMKKLHDIREITVERMRH"
     gene            8979..10025
                     /gene="ilvC"
                     /locus_tag="ACGI5H_002605"
     CDS             8979..10025
                     /gene="ilvC"
                     /locus_tag="ACGI5H_002605"
                     /EC_number="1.1.1.86"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436646.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ketol-acid reductoisomerase"
                     /protein_id="HFG9698303.1"
                     /translation="MSNKNKYHKNKKKYWEEMKMARMYYEKDVDLEVLKNKKVAVLGY
                     GSQGHAHAQNLRDNGVHVVIGLYDGSKSAQKAKEDGFEVKSVAEATKESDLTMMLMPD
                     EKQKKVYEESVKDNLKEGQTLAFAHGFNIHYNQVQPPEFVDVVMVAPKGPGHLVRNVF
                     TKGSGVPALFAVYQDYTKKATETVLAYAKGIGATRAGVLETTFKEETETDLFGEQSVL
                     CGGISELIKLGYKTLVDAGYQKEVAYFECLHEMKLIVDLIYEGGFERMRYSISDTAEY
                     GDYVSGKRVITDVAKQGMQNVLEDIQNGKFAKAWIKENEEGRENFLKTREEEYNTEIA
                     EVGRNLRSMMSFLK"
     gene            10078..11766
                     /gene="ilvB"
                     /locus_tag="ACGI5H_002606"
     CDS             10078..11766
                     /gene="ilvB"
                     /locus_tag="ACGI5H_002606"
                     /EC_number="2.2.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429802.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000287 - magnesium ion binding [Evidence
                     IEA];
                     GO_function: GO:0003984 - acetolactate synthase activity
                     [Evidence IEA];
                     GO_function: GO:0030976 - thiamine pyrophosphate binding
                     [Evidence IEA];
                     GO_function: GO:0050660 - flavin adenine dinucleotide
                     binding [Evidence IEA];
                     GO_process: GO:0009082 - branched-chain amino acid
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="biosynthetic-type acetolactate synthase large
                     subunit"
                     /protein_id="HFG9698304.1"
                     /translation="MNGAKVILECLKKEGIDTIFGYPGGAVIPLYDALYDYSDDFKHI
                     RTSHEQGLVHAADGYARSTNTVGVCFTTSGPGATNAITGIATAFMDSSPMVVISGQVP
                     TSLLGKDSFQEIDITGATLSMTKHNYLVRNTKELVPTIKEAFRVANSGRKGPVLVDVP
                     KDLFLAEMDFSGEDYDLCQIDDYMDYKSDFDLDDETNIKLLNEAIDIIKESKKPIIYA
                     GGGVKSSDSEEILEKFATKIDTPVLNTLMGLGNIDRKNELSLGMVGMHGSRESNLALS
                     NSDLVIAIGARFSDRVISKSSEFAKNAKIIHIDIDPSEISKNIESNVSLVGDVKLVLS
                     LLIERVESKNNSNWKEEIKRFRKSEGVQTYEFHPQNILKKINEKYETLKKPTVVVTDV
                     GQHQMWAAKYWNFKGNKSFITSAGLGTMGFGLGAAIGTKVGNVDKNVVLVTGDGSFRM
                     NCNELATVANYNVPMLILLLNNRTLGMVRQWQKLFSNQRYSQTDINENVDYVKLVNAY
                     NIDGYKVSSMEELGKALDMIDFNKPVFLQCDIDKDYDVYPIVAPNDALENLICN"
     gene            11977..12654
                     /locus_tag="ACGI5H_002607"
     CDS             11977..12654
                     /locus_tag="ACGI5H_002607"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420135.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="manganese catalase family protein"
                     /protein_id="HFG9698305.1"
                     /translation="MFKHDKALLKEVKVERPNPQYAVLMQEQLGGANGELKAAMQYLS
                     QSFRIKDPQIKDLFLDIAAEELSHMEMVAQTINLLNGHDVDYNAVNTGEIETHVLTGL
                     SPVLINSSGAPWTANYVTVTGDLVADLLSNIASEQRAKVVYEYLYRQIDDKYVKETID
                     FLLNREEAHNALFRDALNKVKDTGSNRDFGVTEDSKLYFDLSTPGPNHDTKIDINPPS
                     FEKPLKK"
     gene            12823..14859
                     /locus_tag="ACGI5H_002608"
     CDS             12823..14859
                     /locus_tag="ACGI5H_002608"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429971.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin domain-containing protein"
                     /protein_id="HFG9698306.1"
                     /translation="MDSNRKPNNLINEKSPYLLQHAYNPINWYSWNDEAFKKAKEEDK
                     PIFLSVGYSTCHWCHVMEKESFEDEEVAEIMNRNFVAIKVDKEERPDVDSVYMTVCQA
                     MTGSGGWPMTIIMTPDKKPFFAGTYFPKYSRYNRPGVIDLLENVSEKWNTSRDILIKS
                     GDEIIEALKDDFGVKNTEGDLSKEMLSSSVRVFKAIYDEKYGGFGNAPKFPSPQNLMF
                     LMKYYSIEKDKDVLKMVEKTLDGMYRGGLFDHIGFGFSRYSTDKKWLAPHFEKMLYDN
                     AMLTIAFLDAYKITKKELYKEIAIKTIDYVVREMKDKEGGFYSAQDADSEGEEGKFYT
                     FNPLEIIEVLGEEDGIFFNNYFDITSSGNFEGKSIPNLIKNKEYERHNEKIADLSKKV
                     FEYRKERTSLHKDDKILTSWNALMIVALTKAYSTLKNDIYLEYSNKCLNFINNNLVNE
                     SGRLLARYRDGSSDYLAYLDDYAFLIWAYIELYESTFNMKYLEKALNLNESCINLFWD
                     YEKSGFYIYGKDSENLIARPKDLYDGAIPSGNSVQLYNLIRLAKITGDNRLEEMSYKQ
                     LKLYVDNVKSSPAGYSFYMLSLMFELYSTKEIICIFKEDSDLIAFKELISENFIPNAT
                     FLAKKYNEENTIIGFLNNYRLKDDKISYYVCQSNSCSQPINDLQKLKDMILGVE"
     gene            complement(15050..15616)
                     /locus_tag="ACGI5H_002609"
     CDS             complement(15050..15616)
                     /locus_tag="ACGI5H_002609"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429973.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HFG9698307.1"
                     /translation="MDYSNELKELFLMNQTYATLFTLTNKIQIEGDKYFGILTSRQYM
                     TILSILHLPEEETTLNNIARKMGTSKQNINRLVANLEKNGYVDVIPSPHDKRAINVKV
                     TDLGKKVMVTCSRTGINFMADVFHEFTKDELETLWSLLKKMYRFNGEEQDGFEEDANF
                     MEYEEIDKIKSEALEEFAKRRKRVNKND"
     gene            15904..16839
                     /locus_tag="ACGI5H_002610"
     CDS             15904..16839
                     /locus_tag="ACGI5H_002610"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436568.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lysophospholipase"
                     /protein_id="HFG9698308.1"
                     /translation="MKCTNFTFKGEEGLDIYTYKWEDENIKKPKAVIQIAHGMAETAQ
                     RYETFAKVLTKNGYIVYINDHRGHGKTAKIIENVGHLAEKEGFRCLVEDMYTLTNIIK
                     KENEDLPIYLFGHSMGSFASQRYIMDYSNNLSGLILCGSNGKQGIILNLAHLIINREI
                     KKYGRRSKSNKINNLIFGGEIIRRNEKTKFDWLSRDKEQVEKYINDPFCGVVCSCGFF
                     YDLVQGLKEIEDKENLKKVPLDIPIYIISGDKDPIGKNGKGVLRLRDRYIKLGVKDVT
                     CKLYKDGRHELLNEINREEVFEDIICWLNNKIEIL"
     gene            17304..18518
                     /locus_tag="ACGI5H_002611"
     CDS             17304..18518
                     /locus_tag="ACGI5H_002611"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018112778.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HFG9698309.1"
                     /translation="MQIKIGKVIQCLRKERNLTQEQLAKFIGVSTPAVSKWESGNSYP
                     DIELLPLLADFFNVSIDKLLNYKIDLSEEEVMKIYKELESGFARIEIDLSTEEPKEEF
                     RQDLESVKKLSNMYIEKYPKSYLLKLRICSLYQMYSYKFGKSELNDRVKETTNILEDI
                     VRNTDDIQIKETALIILSNAYCMLEDYEKAELYLNMIHKSIGDTSVNLAMIYLKQNRL
                     EEAEILLQNKLFSNVFNISMDCKGIINVYKNQYKELKKKLENRNFNKNAIEREMEYIK
                     NKLLGYANLSLEIKKMLSEDKGAFFSMYMDYMELSLIFLFFNMKEEAKKALYSLKEIL
                     EKYPIHESLDVSQMRFFDKVESKNLYTFNIYTNLLIVLNDDSYNELREEPIFKDVIEK
                     ILDMEKMLKNKE"
     gene            complement(18938..19459)
                     /locus_tag="ACGI5H_002612"
     CDS             complement(18938..19459)
                     /locus_tag="ACGI5H_002612"
                     /EC_number="2.3.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902626.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016747 - acyltransferase activity,
                     transferring groups other than amino-acyl groups [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HFG9698310.1"
                     /translation="MKFERLRTSENKLYYKAMELYKISFPFHKQRKSSLQAEILKNKE
                     YQFNLIYDKNQFVGIILCWETDNFIYVEHFCIFPEIRNNRYGQRALELLNKKGKTIIL
                     EIDLPIDEISIYRKAFYERVKYKTNNYEHIHPPYHKKFNGHNLIVMSYPEKLSKMEYD
                     KFNHYLRNNVMSF"
     gene            19815..20612
                     /locus_tag="ACGI5H_002613"
     CDS             19815..20612
                     /locus_tag="ACGI5H_002613"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902627.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="G5 domain-containing protein"
                     /protein_id="HFG9698311.1"
                     /translation="MEKREKRIIISSLLSVSILMGLASIYSILNKEDISLTVKGQEQK
                     VSSFKKTVEELLDEQGVKYNSEDKINPSLDTELKDDMKIKVVKVTKSKKEEIEKIPFD
                     TKHVNDSNLLKGKSKVYQEGQEGEKKLVYNLTYHDGKLVKKVLSKEVISKEPTTKIIK
                     YGTKEKVLIASRGANIRGGKHMKVVATAYAGDTITSTGTTPRWGVIAVDPRVIPYGTK
                     VYIPKLGMTFVAEDCGGAIKGNRIDIFMNSEGKASNWGRKSIDIYLH"
     gene            20722..21312
                     /locus_tag="ACGI5H_002614"
     CDS             20722..21312
                     /locus_tag="ACGI5H_002614"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429982.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SGNH/GDSL hydrolase family protein"
                     /protein_id="HFG9698312.1"
                     /translation="MKIVCLGDSLTYGFGVSRSNSWTNIVNKETRLEIVNKGINGDTT
                     SGMLARFNEDVVKNSPDIVFIMGGTNDFIAGAGNEIINSNIMAMVHQSYSKNIIPIIG
                     IPLKPDIPNVREDWSCFTDFNIVSQNLESYSYWIKKFCMTFNTNFVDFYSEYNKNMEL
                     EGYKKLYFDGLHPTKEGHRIMADIFINSINKYIEEL"
     gene            21378..23075
                     /locus_tag="ACGI5H_002615"
     CDS             21378..23075
                     /locus_tag="ACGI5H_002615"
                     /EC_number="5.4.2.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902629.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016868 - intramolecular
                     phosphotransferase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phospho-sugar mutase"
                     /protein_id="HFG9698313.1"
                     /translation="MDYTKTYEEWIKGSYFDEDTKLELENIKNNEKEIEDRFYKDLEF
                     GTAGLRGIIEAGTNRINKYTVRRATFGLANYILENTTKEETSRGVVIAHDNRHKSRQF
                     CIESANTLAACGIKAYIFDSLRTTPELSFAVRSLNAIAGIVITASHNPPEYNGYKVYW
                     EDGAQVMPEIANAITEKVNSIHDYSTIPTLTEANKNLVVLLDESQDTKFIEAVKSQII
                     RKDLVKNVGKSFKIVYTPLCGTGNVPIRRALKEVGFENIIVVPEEENPDPNFAGLDYP
                     NPEEKKALNRGILLAKEKGADLVIATDPDCDRVGVAVKTTTGEYALLTGNQIGGMLTH
                     YIIEGLKENNKLKENPTIIKTIVTSEFGADIAKANNVDVLNVLTGFKFIGEKIKLFEQ
                     NKNRSYVFGYEESYGYLVGTHARDKDGVVSSLLISEMAAFYYSKGMSLYDGLIELYKK
                     YGFFKEQTISLTLKGIEGVEKIKEIISYFRENQIDYINSIKVVDKKDYKNGIDNLPKS
                     DVLKYFLEDESWVAIRPSGTEPKLKFYIAVKGASDIEADKKIQGLKKYIDDMVEKLK"
     gene            23289..24128
                     /locus_tag="ACGI5H_002616"
     CDS             23289..24128
                     /locus_tag="ACGI5H_002616"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861260.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="YihY/virulence factor BrkB family protein"
                     /protein_id="HFG9698314.1"
                     /translation="MFGIDKKLIEYIIAKSNYSELSSKSAEVSFFLMLSIFPFLIFTI
                     SSIAYIPILHLNKYIALFRNMMPEGAFAVLSSIIVSAIDNRNLKFLAVSFVLTMWTFS
                     RAVKALIKGMNRAYKVKETRSFFKILSISFLFTIMLLVLIFLSMIFLVYGEKIGYFIF
                     NLVGLDEIFIKIWDILRYTVGIITIIVIFTLLYKYTPNKKLTIKESAPGAIFATFAWF
                     LVSFLYSYYTNYYANYEVIYGSIAEIIVLMTWMYFSSWSIVIGYEVNSRLYFRKIRHE
                     MLK"
BASE COUNT         9906 a         2430 c         4215 g         7992 t
ORIGIN      
        1 tggtttttat aattttttta tatttaaaca taactaaaaa taaaagatta ctaaagctaa
       61 gtagagttta ttttatttta ataaataata aagctatttt tctatatatt ggcataatat
      121 atgcttattt aactatgaaa ttaaaattaa ataggattaa tgaggaggaa aaaaatggga
      181 agtaatgaac tgaaaaagac tcttggcgta tcagcagcat tatcaactgt tgttggttcc
      241 gttataggag cgggcgtatt ttttaaacca caagcagtct atacattaac tggaggagct
      301 ccaggtcttg gtatattggc atggttaata gctggaatca taactataac agctggtctt
      361 acagctgcag aggtatcagt tgcgatacca aaaactggtg gaatgatggt atatataaaa
      421 gaaatttatg gagaaaaatt aggtttttta actggatgga tgcaaattgt attattttat
      481 ccagggatga tggcagcatt aggtgttata tttggagaac aagcatcggc actaattggt
      541 agtccatcac ttttacttcc aatagcaatt ggaattataa taatagttgc agggcttaat
      601 atgttaggtt caaaaactgg aggagtcata caaactgttt ctacaatttg taagttaata
      661 ccacttattt taataatggt tgttggattt attaaaggtg gtggaaataa tccaatactt
      721 acacctatgg ttggtgaagg attaagcctg ggtagtgtac taggtcaagt tttaattgct
      781 atattatttg cttttgatgg atggatgaat gttggtactt tagctggaga aatgaagaat
      841 cctggaaaag accttccaaa agctataata ggtggattgt cagttgttat ggctgtttat
      901 tttataataa atttagcgta tctttgggta ttaccagcta atgaattagc aaattatgct
      961 tctcctgcat cagcagttgc tgaagttata tttggttcaa tgggtggaaa aataatatct
     1021 gtaggtatat taatttcagt gtttggagca ttaaatggat ttttactaac tggttcaagg
     1081 gtggcatata ctttagctac agataagact ttaccaaagt atggtatatt ttctaaatta
     1141 aattctgctc aagttccagc aaatgcaata gcattagtat ctgttattgc atctatatat
     1201 gctttgtcag gtcaatttaa tttattaact gacttagctg tatttgctac ttggatattc
     1261 tatgtattaa cttttatagg ggttatgaaa cttagaaaga ctcatccaaa tataccaaga
     1321 gagtataaag ttccattata tcctattgtt cctataatag ctatagcaag tggtatattt
     1381 gttgtagtta atcaattgtg ttttgcaggt atgaaaacta ctatgatatc tataggaggt
     1441 cttgtaataa cagctatagg cttaccagtg tatgcttata tgactagagg agtaaaaaga
     1501 taaaccaagt agtttacaaa tgcttcataa ttaaaataaa agagactgtc tcaaatagag
     1561 ataagtctct tttttattgt taaaatggta aagatatgtt taattttaca aaaaaagagc
     1621 gttccatgaa ctaaaaagtt tattttaagg tattcatttt atttttagtt ttttgattat
     1681 aaaattaaac atctaaaaaa ttatttattt taaaatactt tattttaaag tgttttttat
     1741 caaactaagt ggtatctgta caacaaatat tatacatagc ttttatgaaa attaaatctt
     1801 tctgttatat ataatagaat attgtattat atagaaaata ttacctgatt aatatagtga
     1861 tttataaatg agattagaaa attttatttg ataacaaaaa ttagataata tgaatatata
     1921 atgtatgtat taaaaatgtg gcaaatagtt gttttgctat ttattatttg tttaatattt
     1981 ctaatttata aaaaaaaaat tataaatttt aaaaattata aatgacattt taactagaat
     2041 taattgtaaa aaacactata taatactcaa ttttcaacat tctatacaat tatacagaaa
     2101 ttatacagca taataatcac cgaaataaca aattttaaaa attaagcaaa actttttgtc
     2161 gaagttcaac gtctatatat atgtagtgta aatttttggg ataaaatact acaaaaatat
     2221 aaatgtaaaa atatagtaat attggaggtc gaacgatgag aaataaaaag aaaaaaataa
     2281 atagaaagaa gttgtatttg cttttaagtg ctattgtagt gtgtctggct tttatagtag
     2341 ttggtgttcg cgtcagctct ttaaatatga aggaaaatga aattagtaga aatgcaaaac
     2401 tgtcaagttc tactattaca gatatagtat ctaatacatc aatagaagtt agtaaagggc
     2461 caagtaaaag ttctggaaaa atagcataca taactataga tgatggtcca tctaaattta
     2521 ctgaccagat gataaaaact ttaaataaat acaatgttaa agcaactttt tttatgatag
     2581 atgggaatat gaaggaatat ccacagcaag ttaaaaatat aattaaaaat gggaacacag
     2641 caggttttca tagtgtatca catgatattc acaagcttta tgttactagt acatcagcaa
     2701 aagaggaatt tgatacaaat gatcaaactt tttataagat aactggtaaa cattcaaaag
     2761 taataagaat accttatgga agcaaaccat atacaccaca agcctcttat caggctttag
     2821 ttgatgctgg atataaaatt tgggactggg acttagatac agaagactgg agatctaatt
     2881 cttctcaaat tgtacaaaat gtaaaaaatc atattaagaa tagaaaaggt gaagataaag
     2941 accaacttgt agttttaatg catgagaaaa aacagagtgc agaagcttta gattcagttt
     3001 taaaattctt atcagatgaa ggttatgaat ttgcgccagt agatcaaaac caaataccaa
     3061 aaaattattg gttacgtaat ttagagtagt taaaatataa gaatattgat tgatattttt
     3121 agaaattgag aataaaaatg agtgaggtgt aggtatattg aataaaaaac tttatatagg
     3181 aatggtcgga atattgtctt tgatgatggt tggttgtaat aaaagtttag caaaagtaaa
     3241 tgatgtggaa atcacaaaag aacagtacaa aaaaacaaaa gcagttttat ctgctactaa
     3301 taattatata aatgggcagt ctttagatga attagaaaaa actttggata aaaaaggtag
     3361 aaataaatta gaaaatgtta taatatcgtt tatggtggat aatgaacttt tatatcaaga
     3421 ggctaaggat aaaggactaa ctccaagtaa aagtgaagta gactcaaaat atcaagaact
     3481 agaagataag atgaatttga atacaagcta taaggaaaaa atggacaaag caggtgttga
     3541 taaagattat ttaaaacaag aaatatctag agatttagca atagataaaa ataaaaaggc
     3601 ctttgaagat agaataaaca taagtgataa tgatatggaa gcctactata caagtcataa
     3661 aaaagatttt aatgtagaag aagtaagtgc ttctcagata cttatatcga ctttagataa
     3721 aaataaaaaa gaagtaagca aagataaaaa agaagctttg aagaagaagg cagataatat
     3781 attgactaaa atcaaaaatg gagaaagttt tgaaagtttg gctaaaaaat attcggatga
     3841 taaagcaact ggaaaaaatg gaggacagct aggatatttt acaaaggatg ataaaaatgc
     3901 tgagtttaca aaggaagtgt tcaaattaaa gaaaaatgaa gtttcaaatg tgtttgaaac
     3961 tagttatgga tatcatatag tcaaagttac tgataaaaga gaaagacaaa aaagttttaa
     4021 tgagtgtcag agtttaataa gagaatctat tttaaatgaa aagtatattg agcatataaa
     4081 aaaactgaat gaagatgcta aaatagacag atagaatttc taacagctca atcctagcct
     4141 gtaatcggag ggagatttta caggaatgtt taagagttta aagagaacga aagttgagaa
     4201 atacattatc gataataaag actcttttta tagaatagca tatagttata cgaagaatga
     4261 agaagatgcc ttagatgtgg ttcaagaagc catgtataag gcactatact cagtggaaaa
     4321 tattaaagaa gtaaattata taaagacatg gttttataaa attttagtta gaacgagtat
     4381 agattttatt agaaaaaacc gtaaatataa taatatgaca gatattgacc ttatagatga
     4441 gactggagag tatgataaat atactgattt ggatttaaga agagctttgg aagaattacc
     4501 tattgaatac aaatctatta taatattaag attttttgaa gatttaaaga ttgaagaagt
     4561 agcaataata ttggatgaaa atgtgaatac tgttaaaact aggttatata ctgctttaaa
     4621 aaaactaaaa ttaaaaattg aagagtaggg ataaaaagaa tgacaagcaa agaaaggtta
     4681 aataagttaa aagatgagta tcataaaatt ccaataccca agaaattaga tactataata
     4741 aatcatgaaa aaatagaaaa catatatcga gagaaaaata aaaaagtaaa tagattaaga
     4801 tttaaagttg caatagcctt tgcatgtata tttacagtat tagtaaatat aagtcctgta
     4861 tttgcagaca atttttctaa gatacctgta attggagcaa tagtagaagt aataactata
     4921 aaaaattata gtttaaaaag tgaaaattat gaagctgaga ttgatattcc taaaatacga
     4981 ggtttaaaag ataaaaactt agaacaaaga ttaaacagta gttttatgga agatggaaaa
     5041 aggctttatc atcaattcca agagagaatg gagaagatac aatcatcaaa gaataaagga
     5101 tataaatctt taagtttgag ttatagtgta aaaaataatt ctaaaaaatt tctatcaata
     5161 gagatgacaa aaaatgagat agaggcttca tcatatgtga gtaaggtaca ttatactatt
     5221 gataaaaaaa gacaaatagt tttgactttg ccaatgcttt ttaaagatga taagtatata
     5281 aaagttataa gtgataatat aaaagaacaa atgagagaac aaatgaaaaa ggatagtaca
     5341 aaatcctatt ttatagatca aaaaaaagac ttgcctgttg aagattttaa aacaattaat
     5401 aagtatcagg atttttattt taataaaaat gaagaccttg taatttgttt tgatgaatat
     5461 gaagtagcac ctggttatat gggcgcagtt gagtttgtaa taccatataa agtaataaaa
     5521 gatttgtaaa ttgaatagta gtttatatat aaatctttta aggaggacaa tatgactaca
     5581 tataaaaaac ttaaaaaatc tatatttaaa attgctatat tttcaatatg cttattagct
     5641 tcattagtag atacaaaccc tatatttgca ggtagttcct ttaatgaaac ttcaaatagt
     5701 gatacgataa aggtgttaaa tgctaagagt atcaacttta aacaagacaa ttatgaagtg
     5761 aatgtgagta ttcctaaaat aaaaggttta aaagataaaa ctttagagaa taaattaaac
     5821 aatgagtttt tgcaagatgg gaaaaaaatt tacagtgaat ttcaaaataa aatgaaaaag
     5881 gaagataata agggtcatag atacctaaat gtaatccata atgtcaaaaa taattctaag
     5941 gactttttat caatagaaat gacaaaagaa gagatagaag cttcctcatc tataactaag
     6001 aagcattaca ctgttgataa aaatagagga atactattaa atttaccaat attttttaaa
     6061 gatagtagat atattagagc tataagtgat aatataaaag agcagatgag aaatcaaatt
     6121 aagaaagatg atacaaaatc ttattttata gaccaagata aagactcgcc agtgaaagat
     6181 tttgaatcta taaataagta tcaagatttt tattttaata aaaatggaaa tcttgtgatt
     6241 agttttgatg aatatgaagt agctcctggt tatatgggag cagtagaatt tgtgatacca
     6301 aataaagtaa taaaaagact aagatagata tatagaagat ttttagatag actggtaagg
     6361 agaattatat gaatatatat gaacaagcaa taagattaat agaaaataat gaggatttcg
     6421 catttgctac aataacgtct cattcaggtt caacaccacg tgaaactgga gcaatgatga
     6481 ttgtgaaaaa tgattctact atatttggct cagtaggagg aggtagtgta gaagcagaat
     6541 gtataaaaca tgcaattaat gttataaaaa acagagaatc aatgttgtat aaatttactc
     6601 taaacaaatc tgatgttgca aaactaggaa tgatatgtgg aggtactgga gaaatacaaa
     6661 tagattttat agatagtaaa ttaaaaagta atatagaaaa atttaataag agactaaagg
     6721 aaaatacaag taaagcatat atatttggtg caggtcatat ttcaagagat gttgctgtga
     6781 tactatctct tttagaattt agaacagtag taatagatga tagagaagaa tttgctaatc
     6841 atgaaaggtt tccagaatca gaagtagtag ttttagattc ttttgaaaac ataccagatt
     6901 ttccaactga cgaaaatagt tatataatta ttttaacaag aggtcatcta tatgattcaa
     6961 gtgctttaga atgggctctt aaaagagagg ctggttatat aggtatgatt ggaagtagaa
     7021 caaaaattgg attgacttac gaaaaactca tgaaaaaagg ttttaagaag gaagaattat
     7081 caaaagtaca tgcaccaata ggcataaaat tgaatgctca aacaccagct gaaatagctg
     7141 tatgtatagc tgctgaactt ataaattgta gagctaataa ggaaaaataa actaatgaac
     7201 acagggagta aagatattga tactttaaag gttaatttta gagggattga aataaaagca
     7261 gttttagtat ataaaaatag aaaaaatatt tctataaaaa tagatccatt tggcaaaata
     7321 actgtaatga gtcctcctaa aatatccaaa aaaataataa aagatataat tattgaaaaa
     7381 ggagactgga tacttaaaaa gtcagaaaaa tgtaaaggaa gagaggaagt atataaacaa
     7441 agaatgttta taactggcga aaaatttctt tatttaggtg aagagtacca tttagttata
     7501 aaagaactgt tgagagattc tgtcaaaaaa agtaactgta gaataactat taacgaatat
     7561 caaatagttg ttcagacaaa tgatacaagt acagatttta ttaaaaaatc tttaaaatct
     7621 tggtataaga tggaaagtga aagaatagta ttagagagaa tagattttct taaattaaat
     7681 tgtgaaataa tgaagcaatt agttccagcg agtgttaagg taaaagaaca aaataagaga
     7741 tggggaagtt gtacagctca aaaaaatatt tatataaact caaaaatatc tatggcaaga
     7801 ttagatgtaa ttgattatgt aataatacat gagtttagcc atttagtaca tatgaatcac
     7861 tctaaaaaat tctatgattt agtaaaatcc attatgcccg attataaaga taaagaaaat
     7921 tggctaaaaa taaatggata taaaataata atctgaaaac gattattcca aaatataggc
     7981 gtaaagtata aaagaagtat tattgtgaaa aaaataaata atctgaaaat tttaaaaaaa
     8041 gtcattgaca ttgtaaatga tagggaatat aatctatatt aacaacaaaa cagaattaaa
     8101 atataaaatt aaaaaattaa aagcaatgac agagacaaca atactaatag tgttatccac
     8161 agagaaccaa tgttgctgag aattggtgtt aacagtagta taatgatcac tctggagctt
     8221 ttgtactgaa tatttttagt aagtacaaac gtatgtcagc gttacatgac taaggttaag
     8281 gtaattaatt acccgacctg aaaaaagagg ggtagatgta ttttttatat ctacaaataa
     8341 ggtggtaccg cggaatataa ctttcgtcct tataagtaat atttatattg cttataaaga
     8401 tgaaagtttt tttattttaa gcgatataaa taaatttaat ccatataaaa ttaataaaaa
     8461 aataataaaa ataaggaggg atttttatgg aaaatactgt atatgctaaa ttaaaccaag
     8521 gaatagattc ttttttaaga gtggctatga ctctaagaag aagagaggtt gatatacaat
     8581 caataagtat gactgtagat aatatgaata attcaggtat aaaattaata gtaaatgaag
     8641 aaaagacatc cttagattct gtcttaaacc atatgaaaaa actacatgat ataagagaga
     8701 taactgttga aagaatgaga cattaattaa atatatttta taaagctaaa gataaatatg
     8761 cttattttaa aataaaaaac taaagataaa tattaaataa gaaaaatctt agattaaaat
     8821 ataagtgtca ttgaatttat tagtttatca cagttaataa atttattagt ttgttgtagc
     8881 taataaaaac tgaaaattct aaaattataa ttgtaagatt atataaattt agaatttaaa
     8941 tctgttgaat aatattaaaa caatgataat gagtatgaat ttctaataaa aataaatatc
     9001 ataaaaataa gaaaaagtat tgggaggaaa tgaaaatggc aagaatgtat tatgaaaaag
     9061 atgtggattt agaagtttta aaaaataaaa aggttgcagt tttaggttat ggaagtcaag
     9121 gacatgcaca tgcacaaaat cttagagata acggtgtaca tgtagtgata ggtctttatg
     9181 acggaagtaa atcagcacaa aaagcaaaag aagatggatt tgaagttaag agtgtagcag
     9241 aagctacaaa agaaagtgat ttgacaatga tgttaatgcc tgatgaaaaa caaaagaaag
     9301 tttatgaaga gagtgtaaag gataacttaa aagaaggcca gacattagct tttgctcatg
     9361 gattcaatat acattataat caagtacaac caccagaatt tgttgatgtt gtaatggtag
     9421 ctcctaaagg acctggtcac ttagttagaa atgtatttac aaagggaagt ggagttcctg
     9481 cactatttgc agtatatcaa gactacacta aaaaagctac agagacagtt ttagcatatg
     9541 caaaagggat aggagcaaca agagcaggtg ttttagaaac tacttttaaa gaagaaacag
     9601 aaacagattt atttggagaa caatcagtac tttgtggtgg aataagtgaa cttataaaat
     9661 tgggatataa aacgcttgta gatgcaggtt atcaaaaaga agtagcatat tttgaatgtt
     9721 tacatgaaat gaaactaata gtcgacctta tatatgaagg tggatttgaa agaatgagat
     9781 atagtataag tgacacagca gaatatggag attatgtatc tggtaaaagg gtaataactg
     9841 atgttgcaaa acaaggtatg caaaatgttt tagaggatat acaaaatgga aaatttgcaa
     9901 aagcgtggat taaagaaaat gaagaaggac gtgaaaactt cctaaaaact agagaagaag
     9961 aatataatac agaaattgcc gaagttggta gaaatctaag aagtatgatg tcattcttaa
    10021 aataaatata tattaaatgg attagtttga gggaaagagt ggtgtatagt agtgcgtatg
    10081 aatggagcaa aggtaatttt agaatgttta aagaaagagg gaattgacac aatatttgga
    10141 tatcctggtg gagccgtgat acctctttat gatgctctat acgattattc agatgatttt
    10201 aaacatataa ggacatccca tgaacaaggt ttagttcatg ctgcagatgg gtacgcaaga
    10261 agtactaata cagtaggagt ttgttttaca acatctggtc caggagcaac aaatgccata
    10321 actggaatag caacagcttt tatggattct tcacctatgg ttgtaatttc agggcaggtg
    10381 ccaactagtt tattaggaaa agattctttt caagaaattg acataactgg agcaacatta
    10441 tctatgacaa aacataatta tttagttaga aacactaaag aattagttcc tacaataaaa
    10501 gaagctttta gagttgcaaa ttcaggtaga aaaggacctg tacttgtaga tgttccaaaa
    10561 gatttatttt tagcagaaat ggattttagt ggtgaggact atgatttatg tcaaatagat
    10621 gattatatgg attataagag tgattttgat ctagatgatg aaactaatat taagctttta
    10681 aatgaagcaa tagatatcat aaaagaatct aaaaagccta taatatatgc aggtggaggt
    10741 gttaaatctt cagacagtga ggaaattctt gaaaaatttg caactaagat agatacaccc
    10801 gtactaaata cacttatggg gcttggaaat atagatagaa agaatgaatt atctcttgga
    10861 atggttggaa tgcatggaag tagagaaagt aatttagcac tttctaattc agatttagta
    10921 atagcgatag gtgcgagatt tagtgataga gtgataagta aaagttctga atttgctaaa
    10981 aatgcaaaaa taatacacat agacatagac ccatctgaaa taagtaaaaa tatagaatct
    11041 aatgtatctt tggttggaga tgtaaagcta gtccttagtt tattaattga aagggttgaa
    11101 agtaagaata atagcaattg gaaagaagag ataaagagat ttagaaagag tgagggtgta
    11161 caaacatatg aatttcatcc acaaaatata cttaaaaaaa taaatgaaaa atatgaaaca
    11221 ttaaagaaac ccactgtggt agtaactgat gtcggtcaac atcaaatgtg ggctgctaag
    11281 tactggaatt ttaaaggtaa taaaagtttt ataacatcag cagggttagg aactatggga
    11341 tttggtttag gtgcagctat tggaactaaa gttggtaatg tagataaaaa tgtggtttta
    11401 gtcactggtg atggaagttt tagaatgaac tgtaatgaac tagctacagt tgcaaattat
    11461 aatgtaccta tgcttatttt actactcaat aatagaacat taggaatggt aaggcaatgg
    11521 caaaagttat tttccaatca aagatactct caaactgaca ttaatgaaaa tgtggattat
    11581 gttaaactcg taaatgcata taacattgat ggatataagg tatccagtat ggaagaatta
    11641 ggaaaggcgc tagatatgat agattttaat aaacctgtat ttttgcaatg tgatatagat
    11701 aaggattatg atgtttatcc tattgtagca cctaatgatg cattggaaaa tttgatatgt
    11761 aactaaaact tatactgaat attgataaaa ttttttatta aatttttatt agtattcagt
    11821 ttttgttgtt tagagataga ttggcatttt ttatttttgc aaataaatca atgactatat
    11881 aattaagaac ttattaaatt ttaattatac aatttagaat agtattacaa cttaagtaaa
    11941 taataatttt gaataataat ttacggaggt attcatatgt ttaaacacga taaagcatta
    12001 ttaaaagaag taaaagtaga aagaccaaat cctcaatatg ctgttttaat gcaagaacag
    12061 ttgggtggtg caaatggaga gttaaaagca gctatgcaat acttgtccca aagttttaga
    12121 ataaaagacc ctcaaataaa agatttattt cttgatatag cagcagaaga gcttagccat
    12181 atggaaatgg tagcacaaac tataaattta ttaaatggac atgatgttga ttataatgca
    12241 gttaatacag gcgaaataga aacacatgta ttaactggtc tatcaccagt cttaataaac
    12301 tcatcaggag ctccttggac tgctaattac gttacagtta caggggattt agtagctgac
    12361 ttactttcaa atatagcttc tgaacaaaga gctaaggtag tttatgagta cttgtataga
    12421 caaatagatg ataaatatgt aaaagaaaca atagatttct tacttaatag agaagaagca
    12481 cataatgctc tatttagaga tgctttaaat aaagttaaag atacaggttc aaatagagat
    12541 tttggagtta cagaagattc taaattatat ttcgatttgt ctactccagg gccaaatcac
    12601 gatactaaga tagatattaa tcctccttct tttgaaaaac ctttaaaaaa ataatttgat
    12661 attttttatt ttgttttagt agttataaaa attatttact agaagaatta attatatgaa
    12721 aaattaaata tgtatagtta aaaatgggta tacacttatt ataagtgtat atctatttgt
    12781 ttattgcaaa acatataata aaataacaaa tgaggtggta ttttggacag taatagaaaa
    12841 cctaataatc taataaatga aaaatctcca tatcttttac agcatgctta taatcctata
    12901 aactggtata gttggaatga tgaggctttt aaaaaagcaa aagaagagga taaaccaata
    12961 tttttaagtg taggatattc aacatgtcat tggtgccatg ttatggaaaa agaatctttt
    13021 gaagatgaag aagttgctga aataatgaat agaaactttg tggcaataaa agtagataaa
    13081 gaggaaagac ctgatgtaga tagtgtgtat atgacagttt gccaagctat gacaggtagt
    13141 ggtggatggc caatgaccat aataatgaca ccagataaaa aacctttttt tgcgggaaca
    13201 tatttcccaa aatattcaag gtataataga cctggagtta tagatttatt agagaatgta
    13261 tctgaaaagt ggaatacaag cagagatata ttaataaaat ctggagatga aataatagaa
    13321 gctcttaagg atgattttgg tgtaaaaaat actgagggtg atttatcaaa agagatgttg
    13381 agttcatcag ttagagtatt taaggctatt tatgatgaaa agtatggtgg ttttggtaat
    13441 gctcctaaat ttccaagtcc tcagaatctt atgtttttaa tgaaatatta tagtatagaa
    13501 aaagacaaag atgtgttaaa aatggtggaa aaaactttag atggaatgta tagaggaggc
    13561 ttgtttgatc atattggatt tgggttttca agatactcta ctgataaaaa gtggttggct
    13621 cctcattttg aaaaaatgct atatgataat gctatgctta ctatagcttt tttagatgcg
    13681 tataaaataa caaagaaaga gttgtataaa gaaattgcta taaaaactat agattatgta
    13741 gttagagaga tgaaggataa agaaggtggg ttttattcag cacaggatgc tgatagtgaa
    13801 ggtgaagaag gtaaatttta tacatttaat cctcttgaga taattgaagt tttgggtgaa
    13861 gaagatggaa ttttctttaa taattatttt gatataacta gtagtggaaa ttttgaaggc
    13921 aaaagtattc ctaatcttat aaaaaataaa gaatatgaga gacataatga aaagatagct
    13981 gaccttagta aaaaggtatt tgaatataga aaagaaagaa catctttgca taaagatgac
    14041 aagatactta catcatggaa tgcattgatg atagttgctt taacaaaggc atatagtact
    14101 ttaaaaaatg acatatattt agagtattca aataagtgtc ttaactttat aaataataat
    14161 cttgtaaatg agtcaggtag attattagct agatatagag atggaagttc cgactattta
    14221 gcatatttag atgattatgc ttttttaatc tgggcgtata tagagcttta tgagtcaaca
    14281 tttaatatga aatatttaga aaaggcttta aatttgaatg aaagctgtat caaccttttt
    14341 tgggattatg aaaaaagtgg attttatata tatggtaaag atagtgaaaa tttaatagca
    14401 aggccaaaag atttgtatga tggagctatt ccatcaggaa attctgttca attatacaat
    14461 cttataagac ttgcgaaaat tactggagat aatagacttg aagaaatgtc atataaacaa
    14521 ttaaaactgt atgtggataa tgtaaagagt tctccagctg gctacagctt ttatatgctt
    14581 tcattgatgt ttgaacttta ttctactaag gaaattatat gtatttttaa ggaagattct
    14641 gatttaattg cctttaaaga attgataagt gaaaatttta taccaaatgc aactttttta
    14701 gcaaagaaat acaatgaaga aaacactatt ataggttttt taaataacta tagattgaag
    14761 gatgataaga ttagttatta cgtgtgtcaa agtaatagtt gtagtcaacc aattaatgat
    14821 ttacaaaaat taaaagatat gattttagga gtagaataat cataatagtg aaaaaggaga
    14881 tgctttaaaa taaaagtcta atcatctcct ttttttgtac aaaaaacaga aaaagagttc
    14941 ctgagaacac ctaatctatg taatgattgt tttgttaaaa aataaaaatg acattatagt
    15001 tatataaaat attgtactat aaaaaagtag tattatagat gcgatagtat taatcgtttt
    15061 tatttactct ctttcttctt tttgcaaatt cttcaagtgc ttcagattta attttatcta
    15121 tttcttcata ttccataaaa ttagcatctt cttcaaagcc atcttgttct tcaccattaa
    15181 aacgatacat tttttttagt aaactccata aggtctctaa ttcatctttg gtaaattcgt
    15241 gaaatacatc tgccataaag tttattccag tcctactaca tgttaccata accttttttc
    15301 ctaagtctgt aactttaaca ttaattgctc tcttatcatg aggacttgga attacatcaa
    15361 catatccatt tttttcaaga ttagcaacta gtctatttat attttgttta cttgtaccca
    15421 tttttcttgc aatattattt aatgttgttt cttcctctgg taaatgaaga attgataaaa
    15481 tagtcatata ctgtcttgaa gtaagtatac caaaatattt atctccttct atttgtattt
    15541 tgtttgtaag ggtaaaaaga gttgcatatg tttgattcat taaaaagagt tcttttagtt
    15601 catttgaata atccatgaaa tatatctcct ttatttttag atgttgtttt gtcgaaaaca
    15661 gaatatcatg aattaattct aatgtcaata tggtgtcaaa atatattaaa gtattacttt
    15721 tttatgtaac tattaattaa ttaaattatt gtataatttt atgtaaaaac ttctatgtac
    15781 caatgataac ttctatgagg aattaataat tcttaaattt tttagaaaga ttttgacttg
    15841 aaaatacttg taatataata tataaattaa tatactgaat aaaatcaatc tggagggata
    15901 attatgaagt gtacaaactt tactttcaaa ggagaggaag gtttagatat atatacatat
    15961 aaatgggaag atgaaaatat aaaaaaacca aaggcagtta tccaaattgc acatggaatg
    16021 gctgaaactg cacaaaggta tgagactttt gccaaggtac ttactaaaaa tggttatata
    16081 gtatatatca atgaccatag aggtcatggg aaaactgcaa agataataga aaatgttgga
    16141 catttagctg aaaaagaagg atttagatgt cttgtagagg acatgtatac tttaacaaat
    16201 attataaaga aagaaaatga agatctgcca atttatctat ttggacacag catgggttca
    16261 tttgcaagtc aaagatatat aatggattac agtaataatt tatctggtct tatactatgt
    16321 ggttcaaatg gaaagcaagg aatcattcta aatcttgctc atctgataat caatcgtgag
    16381 attaaaaagt atggaagacg ttctaaaagt aataaaataa ataatttgat atttggcggc
    16441 gaaataataa gaagaaatga aaagactaag tttgactggt taagtagaga taaagaacaa
    16501 gttgaaaaat atataaatga cccattttgt ggagtagtgt gtagttgtgg ctttttttat
    16561 gatttagttc aagggttaaa agaaattgag gataaagaaa acttaaaaaa agtgccactt
    16621 gatataccta tttacataat atctggagat aaagacccca taggaaaaaa tggtaaagga
    16681 gtcttaagac taagggatag atatataaaa ttaggagtaa aagatgtaac ttgcaaactt
    16741 tacaaagatg gaaggcatga attgttgaat gaaataaata gagaagaagt ttttgaggat
    16801 ataatttgtt ggttaaataa taaaatagaa atattgtaat aaaaaaatat aatgatatat
    16861 ttactttaaa tttatttata tataatattt gaaaagtgga ttatgtatat gcaaagtaga
    16921 aaagagagag cccagaagtg attttttgct ataatgccat ttattgaata ggtgggtgtt
    16981 attataaata aattattaac actcagtatt attatcattg tatatggaat ttattttatt
    17041 taaaattcct tgaaagttta aatatagtaa gttgtagtaa agagaaaata taaatattta
    17101 aatgctattt aatgtgaatc tattaattag gttatactta aacttaatta atagatttta
    17161 tatttcaaga caatgagata gggttttaga ttaaaatata accaatggtt aaattacaga
    17221 cattttgtta actttccctc gatttactag taaatatttt ttttatatac ttaaattaca
    17281 acagatgtac tagggaggta tatatgcaaa ttaaaatagg taaagtcata cagtgtctta
    17341 gaaaagaacg aaatttaact caagaacaat tagcaaagtt tataggtgtg tcaacaccag
    17401 cagtatctaa gtgggagagt ggaaattctt acccagatat agaattattg cctttattag
    17461 cagacttttt taatgtgtct attgataagc ttttaaatta caagattgat ttaagtgaag
    17521 aagaagtaat gaaaatttat aaagaattag aatcaggctt tgctagaatt gaaattgatt
    17581 tatcaacaga agaaccaaaa gaagaattta gacaagattt agaatctgta aaaaagcttt
    17641 ccaatatgta tatagagaag tatcctaaaa gctatttatt gaagctaagg atatgttcgc
    17701 tgtatcagat gtattcatat aaatttggta agagtgaact taatgacaga gtaaaagaaa
    17761 caacgaatat tcttgaagat atagtgagaa atacagatga tatccaaata aaagaaacag
    17821 ctcttattat attatcaaac gcatattgta tgttggagga ttatgaaaag gcagagttgt
    17881 atttaaatat gatacataag tcaatagggg atacaagtgt taatttagct atgatatatt
    17941 taaagcaaaa tagacttgaa gaagcagaaa tattgcttca aaataaattg tttagtaatg
    18001 tatttaatat aagcatggat tgtaagggaa taattaatgt atacaaaaat caatacaagg
    18061 aattaaagaa aaaattggag aatagaaatt ttaataaaaa tgcaattgag agagaaatgg
    18121 agtatataaa aaataagttg ctggggtatg caaatctttc tttagaaata aaaaaaatgc
    18181 tcagtgaaga taaaggtgca ttttttagta tgtatatgga ttatatggaa ttatctctaa
    18241 tttttttatt ttttaacatg aaagaagaag caaaaaaagc tttatatagt ctaaaagaaa
    18301 tattagaaaa atatcctata catgaaagtt tggatgtaag tcaaatgaga ttttttgata
    18361 aggtagagtc taaaaattta tatactttta atatatatac aaacttgtta attgtactta
    18421 atgatgacag ttataatgag cttagagaag aaccaatttt taaggatgta attgaaaaga
    18481 ttttagatat ggaaaaaatg ttgaaaaata aagaataagt aaaaatttaa tataggactt
    18541 aaagattaat caaattaaaa gaaagtgttt caaaataaaa atttgaatca ccttttttgt
    18601 cggtcttaaa cagttattta gaaaaataga ggtttcaaaa tagaaatctg aattatctgt
    18661 attattacac aaaaatagaa acctaaattt ataaaaatag aataaaattt gttatataaa
    18721 atgtaatttt gtctataaaa tctcacctgt tttcttaact ttaagcgtga aaaagaggat
    18781 gtatcatgaa ttttttagtt catgatgcat cctgctttgt atgaaatcca atatatcttt
    18841 attatttaaa caatggaaaa gagtcttatt tatattttga gacatctctt ttatttaatt
    18901 atgaagtttt atacagttca ataaatagga attatattta gaaactcatg acattatttc
    18961 ttagatagtg attaaattta tcatattcca ttttagataa cttttctggg taagacatta
    19021 caatcaggtt atgcccatta aattttttat ggtatggtgg atgaatgtgt tcataattat
    19081 ttgtcttata ttttactctt tcatagaacg ccttgcgata aattgaaatc tcatcaattg
    19141 gaaggtcaat ttctaaaata atagtttttc ctttcttatt taaaagctct aacgctcttt
    19201 gcccatatct attattgcga atttctggaa aaatgcagaa atgttctaca tagataaagt
    19261 tatctgtttc ccaacataaa attatgccga caaactggtt tttatcataa attaaattga
    19321 attgatattc tttatttttc aaaatttctg cttgcaaaga agattttctt tgtttatgaa
    19381 atgggaaact aattttatat aattccatag ccttgtaata taatttattt tcactggttc
    19441 ttaaccgttc aaatttcact ttactcctcc taatcacgaa aattccaatt tatttatgag
    19501 ttcattttac catagtcagt atttgcatac aatgtgtttt aagttgagtg tcatttcttt
    19561 cttttattta tgcttatatc tcatagtcta agagataatt gcttaagaca taactaaaaa
    19621 ctattatatt aagctttgat aatctaaaaa cagtatattt atggactttt ctaggtctaa
    19681 aagtaatctt aataatttta gaagttacaa aaaagttaca taaatttgga aagctataat
    19741 atacatatat aatataaggt taaaactgta atgaataata ttaatttaaa atttgaacat
    19801 ggaaggagat tattatggag aaaagagaaa agaggataat aatatcatct ttattaagtg
    19861 tatcaatttt aatgggtttg gcaagtatat attctatatt aaataaagaa gacataagtt
    19921 taaccgttaa aggtcaagag caaaaagtat cttcctttaa gaaaacagtt gaggaacttt
    19981 tggatgaaca gggtgtaaag tataattctg aagataagat taatccaagt ttagatacag
    20041 agttaaaaga tgatatgaaa ataaaagttg ttaaggtaac taaaagtaaa aaagaagaga
    20101 ttgaaaaaat tccatttgat acaaagcatg taaatgatag taatttgtta aaaggaaaat
    20161 ctaaagttta tcaagaaggt caagaaggag aaaaaaaact agtctataat ttaacttacc
    20221 atgatggcaa gttagtcaaa aaagtcttat caaaagaagt aatatctaag gagccaacta
    20281 caaaaattat aaaatatgga actaaagaaa aagtactaat agcatcaaga ggagcaaata
    20341 taagaggagg caaacatatg aaagtggttg ccactgcata tgcaggagat acaataacat
    20401 ctactggtac aactccaaga tggggtgtta ttgcagttga cccacgtgta ataccatatg
    20461 gaacaaaagt atatatacct aaactgggta tgacttttgt agcagaagat tgtggaggtg
    20521 caattaaagg taatagaata gacattttta tgaacagtga aggaaaagct tcaaattggg
    20581 gaaggaaaag tatagatata tatctacatt aaattagtga atagaataac tttacttgaa
    20641 ggacaaaaaa gtataaaata tgaattaact aaactgttag attattctta aaacataaaa
    20701 atatatctaa ggggggataa gatgaaaata gtctgcttag gagacagttt aacgtatgga
    20761 tttggagtat cacgaagtaa ttcatggaca aacattgtaa ataaagagac tcgattagaa
    20821 atagtaaata agggtataaa tggtgataca acaagtggta tgttagctag gtttaatgaa
    20881 gatgttgtaa aaaactctcc tgatatagtt tttataatgg gtggcaccaa tgattttatt
    20941 gctggtgcgg gaaatgaaat tattaattct aatataatgg ctatggtgca tcagtcatat
    21001 tcaaaaaata ttatacctat aataggtata ccattaaaac cagatattcc aaatgttagg
    21061 gaagattgga gttgttttac tgattttaat atagtatctc aaaacttaga atcatatagt
    21121 tattggataa aaaaattttg tatgacattt aatactaatt tcgtagattt ttattcagaa
    21181 tataataaaa atatggaact agaaggatat aaaaaattat attttgatgg gttacatcca
    21241 accaaagagg gtcatagaat aatggcagac atttttatta attcaattaa taagtatata
    21301 gaagagttat agattacatt aaaatgcttg tttatgcgtc agttgcaata aatacataca
    21361 gtagagaggg gtttattatg gattatacta aaacttatga agagtggata aagggttcat
    21421 attttgatga agatacaaag ctagagttgg agaatataaa aaataatgaa aaagaaatag
    21481 aggatagatt ctataaggat ttagaatttg ggactgcggg tcttagagga ataattgaag
    21541 caggaacgaa tagaataaat aagtacacag ttagaagagc tacttttgga ttggcaaact
    21601 atatattaga aaacacaaca aaagaagaaa caagtagagg agtagtaata gctcatgata
    21661 atagacacaa gtctagacaa ttctgtatag aatctgcaaa tactttggca gcatgtggta
    21721 taaaagcata tatatttgat agtttgagaa ctactccaga attatctttt gctgttagaa
    21781 gcttaaatgc aatcgctggt atagtcataa cagcaagcca taatcctcca gaatataatg
    21841 gatataaggt atactgggaa gatggagcac aagttatgcc agagattgca aatgcaataa
    21901 cagagaaagt aaatagtata catgattata gtacaatacc aaccttaacg gaagctaata
    21961 aaaatttggt agttttgttg gacgaatcac aagatactaa atttatagaa gcagtaaaaa
    22021 gccaaattat aagaaaagat ttagttaaaa atgtaggtaa aagctttaag atagtttata
    22081 cacctctttg tggaacaggg aatgttccaa taagaagagc attgaaagaa gttggttttg
    22141 aaaatataat tgtagttcca gaagaagaaa atccagaccc aaattttgca gggcttgatt
    22201 atccaaatcc agaagagaaa aaagctttaa atagaggtat attactcgca aaagaaaaag
    22261 gagcagacct tgtaatagca actgacccag attgtgatag agtaggtgta gcagtaaaaa
    22321 ctactacagg tgagtatgct ttacttacag gaaatcaaat tggtggtatg ctgacacatt
    22381 atataataga aggattaaaa gaaaataata aattaaaaga aaatcctaca ataataaaaa
    22441 ccatagttac atcagaattt ggagcagata tagctaaagc aaataatgtt gatgtattaa
    22501 atgttcttac aggttttaaa tttattggtg aaaaaataaa attatttgaa caaaataaaa
    22561 atagaagtta tgtatttgga tatgaagaaa gttatggtta cttagttggg actcatgcta
    22621 gagataaaga tggtgtagtt tcttcattgt taatatctga aatggcagca ttttactatt
    22681 caaaaggtat gagtttatat gatggcttaa tagaacttta taaaaagtat ggatttttca
    22741 aagaacagac tatatctttg actttaaaag gtatagaagg tgtagaaaag ataaaagaaa
    22801 taatatctta ttttagagaa aatcaaattg attatataaa tagtattaaa gtagttgata
    22861 aaaaagatta taaaaatggt atagataatc ttcctaaatc tgatgtttta aaatactttt
    22921 tggaagatga atcttgggta gctataagac catctggaac agaaccaaaa cttaaatttt
    22981 acatagctgt aaaaggagct agtgatattg aagcagataa aaagattcaa ggtttgaaaa
    23041 agtatataga tgacatggtc gaaaaattaa aataaaatat tattatttta taagataatt
    23101 ttgtaataat atttatttag ctgaaaatta taatttactt tcattgagta gaatatggaa
    23161 atgttagtag aattgttatt ttcagctttt atttgtgtta tttttactta aataattata
    23221 ttatagaatg aatctgagta taattaatat tgtataatga aattaatttg atagaaaagg
    23281 ggatatttat gtttggtata gataagaaat tgattgaata tataattgca aaatccaatt
    23341 acagtgaatt aagttcaaag tcagcagaag tatctttctt cttaatgttg tccatatttc
    23401 cttttttaat atttacaata agttctatag cttatatacc gattcttcat ttaaataagt
    23461 atatagcttt gtttagaaat atgatgccag aaggtgcttt tgctgtgtta tcttcaatca
    23521 tagtttctgc aatagacaat agaaacctga aatttttagc agtcagtttt gtacttacta
    23581 tgtggacatt ttcaagagca gtaaaagctc ttattaaagg aatgaataga gcctataaag
    23641 ttaaagaaac taggtctttt tttaaaattt tatctatatc atttttattt acaataatgc
    23701 ttttggtcct tattttttta tctatgatat ttttagttta tggggaaaaa ataggttatt
    23761 ttatttttaa tcttgtagga ttggatgaga tatttataaa aatatgggat attctaagat
    23821 acactgtagg tataataaca ataatagtga tatttacact tttatataaa tacactccaa
    23881 ataaaaagtt aactattaaa gaatctgcgc caggtgctat ttttgctact tttgcttggt
    23941 ttttagtatc atttttatat tcttattata caaattacta tgctaactat gaagtaatct
    24001 atggaagtat agctgaaata attgtactta tgacctggat gtattttagt agttggtcta
    24061 tcgttattgg ctatgaggta aattcaagat tgtattttag aaagataaga catgaaatgt
    24121 taaagtaaag tatttaaaat aaaagagagt atttagtatt ataaatgtaa ttgaattaat
    24181 aaagaaatat tgacatttaa gttaaaaagt ctagaatttt tctgggcttt ttttattttt
    24241 agtataactt gacaaatttt atttaatggg atagttttaa tttataatca tctttaaaaa
    24301 gatgactatt gataagtaag agataaaatt ggtaagtatc aaaaaatata ctaaataaaa
    24361 attatagtcc taatgagtta atttctgtat tttcaaataa tgcagtattt agtcatgtgt
    24421 ttttatatgc gcctgtattt ctaattacca atatattaga ataagctact gtaattagat
    24481 ttagaaaaaa gcgacataaa taattataaa caaataataa attacataaa attaaattta
    24541 ttc
//
LOCUS       DAYAOO010000061        23826 bp    DNA     linear   BCT 12-OCT-2024
DEFINITION  TPA_asm: Clostridioides difficile isolate ST8-SSI-h139-18
            SAMN40601845-rid21577343.denovo.061, whole genome shotgun sequence.
ACCESSION   DAYAOO010000061 DAYAOO010000000
VERSION     DAYAOO010000061.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN40601845
            Sequence Read Archive: SRR28438827
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 23826)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 23826)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-MAY-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-MAY-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002157583.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002157583.1
            Genome Coverage       :: 163x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/11/2024 16:19:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 4,038
            CDSs (total)                      :: 3,963
            Genes (coding)                    :: 3,930
            CDSs (with protein)               :: 3,930
            Genes (RNA)                       :: 75
            rRNAs                             :: 6, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 60
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 33
            CDSs (without protein)            :: 33
            Pseudo Genes (ambiguous residues) :: 0 of 33
            Pseudo Genes (frameshifted)       :: 7 of 33
            Pseudo Genes (incomplete)         :: 25 of 33
            Pseudo Genes (internal stop)      :: 11 of 33
            Pseudo Genes (multiple problems)  :: 8 of 33
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..23826
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN40601845-rid21577343.denovo.061"
                     /isolate="ST8-SSI-h139-18"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Denmark"
                     /collection_date="2018"
                     /collected_by="Statens Serum Institute"
     gene            complement(<1..338)
                     /locus_tag="ACGI5H_002617"
     CDS             complement(<1..338)
                     /locus_tag="ACGI5H_002617"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419653.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall hydrolase"
                     /protein_id="HFG9698315.1"
                     /translation="MIINRSKDSSSNEISFVSKDMGFLLTQSEVSYNFKDKLVEDIAK
                     QVFAENRLSVGTIAKTNVKYTKMFIGVNGYDTIMSAYTEASKKTKKKYMIEANLDKFN
                     VIEKGTVTLNV"
     gene            complement(620..1042)
                     /locus_tag="ACGI5H_002618"
     CDS             complement(620..1042)
                     /locus_tag="ACGI5H_002618"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889143.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage baseplate protein"
                     /protein_id="HFG9698316.1"
                     /translation="MEMWLRQAEDRFRFPVFPSSFSINGKAAVNSSSILKIGEIATFG
                     GVALKSISISSFFPNKDYTFCDYTGFPSPYDCVNKIEKWMKEGFILRFTITETNINME
                     VIIEGFSYEERDGTRDVYFTLDLKEYKRIKIPKVTPKQ"
     gene            complement(1042..3495)
                     /locus_tag="ACGI5H_002619"
     CDS             complement(1042..3495)
                     /locus_tag="ACGI5H_002619"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889141.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9698317.1"
                     /translation="MGNVREEGINMYLTDNYTPKMNQIISVTDNFRRATVAVSLSTNV
                     MASSIKNSIGSASNRVNSLNSSLRKVQTTASSVSSTMTKLSSSINAVSGVIGSLNGSI
                     MILAITIAMIIDYFNKLIQKKNEFNSNIMIILIFKAKSDEVEKTKNKLLGNLKKIGGK
                     VWNIVIKAKDMTKRVISSILGKLKQVEKRPYQGSINLKDMVSSAMGRILPKLMLFKNT
                     FWSGVIAIKDMASGIISKVFPKLRLFAGKVWSGAIAVKDMASGILGSIKGKISDLTNG
                     ATIGVAVKKGVDLLGQEQNQKVVLESVMKRNTGKVNQIDVDDYYGSLVRMANDTPFDP
                     EDVVAMGTKAKMISNITGGKKEKDITQAMVDVRALNMNTSSEQDVSAAFLSAAKGNME
                     SLNTLVGENYKTFDEALEGISVKQMGLAKEMSNTIPGIISGAQTSINNGLKSIVKPFD
                     DILGQGLKKIKTFIESGLGNLAGLSEKMAGKIGNVMNGKIIIGNKYDQMQSRSVKNGK
                     EFSDSTQYRISNEAEKRKMMVENKQERFENHAATMIGNAPKAIVNAGSTLLQNIDFTA
                     LIDSLLPVVNLVNNLLDSINNKSPIAQGLISIFGTIVTTAFQLIGPVVEAVSPIITRI
                     FTFLGEYAPQINNFIETLGVIWKTVWETLGPLLETGWKIIEPILGAFFNILDKVCKIV
                     KDICKWWQTMINKIKNGSITGTVLNLVEKSKKNYKDNPYAGTKAGDSGKAYSGKKGNN
                     AFGLNYVPYNDYQTRLHEGEMVLTKQEANQYRSRKNGGNINIAKLADTIVIREEADIE
                     KITSKLVASIQLAQLGGVL"
     gene            complement(3495..3662)
                     /locus_tag="ACGI5H_002620"
     CDS             complement(3495..3662)
                     /locus_tag="ACGI5H_002620"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428173.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9698318.1"
                     /translation="MYYYWKKKGIRPSLFYAMDKGELKLIEAFFALEIEEEVEKMKHG
                     YGVCPLTGGGM"
     gene            complement(3689..4135)
                     /locus_tag="ACGI5H_002621"
     CDS             complement(3689..4135)
                     /locus_tag="ACGI5H_002621"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428176.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage portal protein"
                     /protein_id="HFG9698319.1"
                     /translation="MSENGLSKNINIVDLLLNSDTENLERPSTIVELKRLSTIFGQEF
                     KVMCRALTISKDEEIQNTCLKIDENMKTDIDLPEMQMLTIIEGVCDLDGKLLFKNKEL
                     MDKFKAPTPKELARKLLLPGEITNLYRILQDVMGYGKNAVIEEVKN"
     gene            complement(4261..4689)
                     /locus_tag="ACGI5H_002622"
     CDS             complement(4261..4689)
                     /locus_tag="ACGI5H_002622"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896262.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail tube protein"
                     /protein_id="HFG9698320.1"
                     /translation="MANMEARNVMSGTWGELWLDGNKVAEVKKFQAKMEFTKEDIIIA
                     GQMGTDTKYIGYKGKGSITLYHVSSRMHKLIGEKIKRGSEPRFVAISKLNDPDSYGAE
                     RIAVKNIAFDDLTLADWEVGVKGEIEAPFTFTEYDFLDII"
     gene            complement(4703..5767)
                     /locus_tag="ACGI5H_002623"
     CDS             complement(4703..5767)
                     /locus_tag="ACGI5H_002623"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861188.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail sheath subtilisin-like
                     domain-containing protein"
                     /protein_id="HFG9698321.1"
                     /translation="MAIGLPSINISFKELATTVKERSARGIIAMVLKDAKALGLNEIH
                     EKEDIPVDLSAENKEYINLALMGNVNTPNKLLVYVIEGEADIQTALDFLETKEFNYLC
                     MPKAVEADKTAIKNWIIKLRDIDKVKVKAVLGKVVGNHEGIINFTTEDVLVGEKKYSV
                     DEFTSRVAGLIAGTPLSQSVTYTKLSDVVDIPKMTKVDAESKVNKGELILIKEAGAIR
                     IARGVNSLTELTAEKGEMFQKIKIVDTLDIIHSDIRKVIIDDYIGKVTNSYDNKCLLI
                     VAIKSYLEELEKSALIESDSTVEIDFEAQKSYLKSKGVDLSYMTLQEIKEANTGSKVF
                     LKAKIKVLDAMEDIDLSIEI"
     gene            complement(5772..6215)
                     /locus_tag="ACGI5H_002624"
     CDS             complement(5772..6215)
                     /locus_tag="ACGI5H_002624"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428180.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF6838 family protein"
                     /protein_id="HFG9698322.1"
                     /translation="MLKYKEILETIIEILKKNFTESIFIDDESVQGSEGSCFFVSILS
                     VICTPVMLNTNNKDIVISIKYLPKPQSKSIRMYEVSDELNKLFNRNIKVTDRKLNITK
                     LEQSIKKEESIYVLNFTFTLNYLDSVYEEDVVYENMEEINLNLGE"
     gene            complement(6464..6904)
                     /locus_tag="ACGI5H_002625"
     CDS             complement(6464..6904)
                     /locus_tag="ACGI5H_002625"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419643.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9698323.1"
                     /translation="MENKKDILFKETDKRLHNYKYLDIKIKNINLDIKRCENEYSGCG
                     AMVYTEKTSNTYNISSSVENEVLKREERLRKLKMEKEDIEIEKEKIENALTCLNDIEM
                     EFFNLFYNSKTKNNMTYISMKLHLDRTSCYNLKKKMIFKLSEIL"
     gene            complement(7009..7206)
                     /locus_tag="ACGI5H_002626"
     CDS             complement(7009..7206)
                     /locus_tag="ACGI5H_002626"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419641.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HFG9698324.1"
                     /translation="MFKNNLKYYRKCKGMTQIQLARKAGITNDYISQIERGIKNPGLL
                     MAKKISSILEQNIEEVFFIQL"
     gene            7375..7695
                     /locus_tag="ACGI5H_002627"
     CDS             7375..7695
                     /locus_tag="ACGI5H_002627"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HFG9698325.1"
                     /translation="MFAKRLRELRKEFGLTQRELGEKVGVSQRVLGYYETENRFPDEH
                     ILNKLADVFNVSVDYLLGRTLVKENIDTVAAHRKNPHEELPEEAQEQLNDYIEFLLNK
                     YKKK"
     gene            7777..8283
                     /locus_tag="ACGI5H_002628"
     CDS             7777..8283
                     /locus_tag="ACGI5H_002628"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419636.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ImmA/IrrE family metallo-endopeptidase"
                     /protein_id="HFG9698326.1"
                     /translation="MNNLDKLFELASQEEIIIHYTTYIAGDLEGLYINKHGIKIISLL
                     SNLKQNSKKLTSILAEELGHHFTSLGYYVSSYNDYYTKIIIDKCENKALKWACEFLIT
                     EEDIINIINSGITCVYEMADILNVDITFFQKRLEFLSLKKQSLQLGNNKYLILTNLPY
                     FYIFDPIS"
     gene            8984..9739
                     /locus_tag="ACGI5H_002629"
     CDS             8984..9739
                     /locus_tag="ACGI5H_002629"
                     /EC_number="5.2.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889131.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003755 - peptidyl-prolyl cis-trans
                     isomerase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase"
                     /protein_id="HFG9698327.1"
                     /translation="MEKKVLATVGEKEITNIDIENALKSLDPYQAMQFKTEEGKKHLL
                     NDLVNQELFFLDAKEEKLDEEEIFKLEMKKIEENVLKQFAINKVLSSVNVTEDEKVKF
                     FEANKSSFSKPESATAKHILVDSDEKAKEILAQIKSEEISFEDAALKHSSCPSKDMGG
                     DLGTFGRGQMVPEFEEAVFSMAKGEVSEPVKTQFGYHIIKLEDLQESTESTFDEVKAE
                     VEKSLLYQKQNEVYGNKINALNAKYGNLVKYND"
     gene            complement(9882..10310)
                     /locus_tag="ACGI5H_002630"
     CDS             complement(9882..10310)
                     /locus_tag="ACGI5H_002630"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889129.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CBS domain-containing protein"
                     /protein_id="HFG9698328.1"
                     /translation="MNILFFLTPKSEVAYIYEDYTIRQALEKMEYHKYSAIPIISKDG
                     KYVGTITEGDFLWTLKNDLNLDLKGLEDVPVTDINRKMDNSPVSINADIEDLVIKSLN
                     QNFIPVIDDQDTFIGIIKRRDVIGYCYEIIRGYKNLANDN"
     gene            complement(10731..10931)
                     /locus_tag="ACGI5H_002631"
     CDS             complement(10731..10931)
                     /locus_tag="ACGI5H_002631"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003230776.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005829 - cytosol [Evidence IEA];
                     GO_function: GO:0001072 - transcription antitermination
                     factor activity, RNA binding [Evidence IEA];
                     GO_function: GO:0003676 - nucleic acid binding [Evidence
                     IEA];
                     GO_function: GO:0003723 - RNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cold-shock protein"
                     /protein_id="HFG9698329.1"
                     /translation="MKTGVVKWFNNEKGFGFISVEGEGDVFVHFSAITGDGYKTLEEG
                     QSVEFEVVDGAKGPQAANVVRL"
     gene            complement(11114..12268)
                     /locus_tag="ACGI5H_002632"
     CDS             complement(11114..12268)
                     /locus_tag="ACGI5H_002632"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905420.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidase domain-containing protein"
                     /protein_id="HFG9698330.1"
                     /translation="MKILKNKNKYIKGIMAFVFLSLATTAGVFLINDLSMKNMEEKVM
                     ESANVEGDDVKDQYKLLLENLFDYRNKAILEKNENILKGLYETDKKFGLWAYENEVKK
                     MKYLENWSSKQGVKFKDIKTRVKIKKIKEKEKDLYGIICSVSTEYKYSYENQKDKENA
                     FRIGTYHYLNVKIIDNQYVITKEWYTDPFADSLNLENIKSDDIRNYIGQQDGVELQLT
                     DEQKKAIDYAHKYCGAAADEEHGMKFNPNYRDYNPEGGDCANFASQIMFESGRFKKNS
                     IWNYSERAGTKAWVNAQAFKNYALYSGRGSLIAKGSYEEVYKEAYNLRPGDFVGYEKK
                     GRITHVSTVTGLDSRGYPLVTCHNTDRMLVPWDLGWSDKSIRFHIIKINY"
     gene            12519..13340
                     /locus_tag="ACGI5H_002633"
     CDS             12519..13340
                     /locus_tag="ACGI5H_002633"
                     /EC_number="2.7.1.35"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428191.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008478 - pyridoxal kinase activity
                     [Evidence IEA];
                     GO_process: GO:0009443 - pyridoxal 5'-phosphate salvage
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxamine kinase"
                     /protein_id="HFG9698331.1"
                     /translation="MQKKVAAINDLSGIGKCSLSVAIPILSALKVQCCPFPTAILSSQ
                     TGYPEFTFLDFTDEMVKYSNVWKNLKVNFDSIYSGFLGSKHQIEIVANFINDYPNAFI
                     VVDPVMGDNGVMYPIFTEEMRQEIKELVKHSDLTTPNLTEACFLTGNDYTKSDYNRDE
                     LIYIAKSVSDLGPSKVVITGILEDDNILNLAYNRDNDHVFFTSVKYNNCSYSGTGDIF
                     TSILCGMLVNKHDLGVAVNTATDFIYKTINYTSQFDTDRNDGVMFENFLSDLTNI"
     gene            complement(13416..14804)
                     /locus_tag="ACGI5H_002634"
     CDS             complement(13416..14804)
                     /locus_tag="ACGI5H_002634"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system sensor histidine kinase"
                     /protein_id="HFG9698332.1"
                     /translation="MLGGKKSNNKKVEKLRTIFIKYLSLFFIMTISIVLLLMLSFSVL
                     LSSGVILPANYAEKQFNKYKEQIISSEKVTEDIIPSIYEYGVYTLDGNLISGTFNKKE
                     SKEVWNLMRDIEERHAYSESYIKFFKKDEVFIIKYKIVSEYSSPILRAYLPKPETLGM
                     IIFSIIFFIEIVILSKVFGKKFNIEMELLKNTTEKIEQQDLDFVVESSKIYEINNVLF
                     SMDKMKLALKDSLEKRWMLEENRKEQISALAHDIKTPLTIIHGNTDLLIEINENPELL
                     EYMEYISKGVTQIEKYINTLIDISKTENGYILNKEAISMSEFIKDVLVQIEALASTKN
                     LDVEFYKQDNLPKNITIDRELLFRAIMNIISNAIDYSPSQSKLYISVSVHNKYLKFVV
                     TDCGSGFSKADLSKATEQFYTGDLSRNSKSHYGMGLYIVNNIVQKHNGTLCIENSVKT
                     GGAMVTIEIPIV"
     gene            complement(14939..15697)
                     /locus_tag="ACGI5H_002635"
     CDS             complement(14939..15697)
                     /locus_tag="ACGI5H_002635"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729590.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lantibiotic immunity ABC transporter MutG family
                     permease subunit"
                     /protein_id="HFG9698333.1"
                     /translation="MRQLIRIFCSDLIKLKRNFIILMHICIALMGMGLFLWYYKVSGA
                     DNILKIVAYLQVIAIAFPLLSSVVCSMFVEQEYYAGNYKHMLTTSNPKYLTLISKYII
                     LVCLGFVATLVSVLGFKFGISKAYFTSSFYMISILILIGCNLFEYILHLFLSLRFGKG
                     TSIGVGIVEMLLSALLLTGLGSGIWQYFPCAWGVRFITIWSSFSSSKTVEYIKVESIK
                     AYQSTGLICGFVTILAFVILCIWFSKWEGKKSEE"
     gene            complement(15699..16415)
                     /locus_tag="ACGI5H_002636"
     CDS             complement(15699..16415)
                     /locus_tag="ACGI5H_002636"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729591.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lantibiotic immunity ABC transporter MutE/EpiE
                     family permease subunit"
                     /protein_id="HFG9698334.1"
                     /translation="MERFIRVEFQKMKGTFGMKLIWIVPVFCILLCGLGGGQNAAFNW
                     WYTTFLPGALTLISSLIVLKDEKSKYRGILPLPIEMKDVWTGKMIYCIICCFIASIIS
                     AIGVVFVGIIYKETISIGQNIIASILIILLFMWQIPLCMFLASKFGMFVTVLTNMFFT
                     IVGVAVFSTTEMWYMFPYSIPSRLMAVVLHILPNGLPVPEGSEFLNNAVILPGVLISI
                     VLFVLFALATRVWFNNREVK"
     gene            complement(16417..17124)
                     /locus_tag="ACGI5H_002637"
     CDS             complement(16417..17124)
                     /locus_tag="ACGI5H_002637"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902422.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lantibiotic protection ABC transporter
                     ATP-binding protein"
                     /protein_id="HFG9698335.1"
                     /translation="MSNYILQVKGVSKKFKEQMAVDNISLAIKSNSIYGLLGPNGAGK
                     STLLKMITGILNPTSGKIMFEGHRWTRKDLSNIGSLIESPAIYENLTARENLKVHTTL
                     LGLPDSRIEEVLETVDLRDTFKKRSGQFSLGMKQRLGIAIALLNHPKLLILDEPTNGL
                     DPIGIEELRELIRSFPKQGITVILSSHILSEVEQVVDEIGIISNGVMGYQGEVSKEQN
                     LEELFMKVVAENRKRGQ"
     gene            complement(17240..17776)
                     /locus_tag="ACGI5H_002638"
     CDS             complement(17240..17776)
                     /locus_tag="ACGI5H_002638"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419598.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipoprotein"
                     /protein_id="HFG9698336.1"
                     /translation="MNKIAVSFLIIATTLLSTACMDYSISAVELVDSKESAVVKKDED
                     AKEETTSKMINSKKTTKIPIEIISKDEKIVKYLQIDEESSLKDKLRLILDTLSNEYFN
                     GLDMEVEVKEKDNLVKINLIEPDKKSRVSWKDDYLNEQNIIYTINNIIKNVIQEEDNS
                     IWIEEVEIYYNGKLIELR"
     gene            complement(17878..18948)
                     /locus_tag="ACGI5H_002639"
     CDS             complement(17878..18948)
                     /locus_tag="ACGI5H_002639"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428197.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4097 family beta strand repeat-containing
                     protein"
                     /protein_id="HFG9698337.1"
                     /translation="MNKKLAIFAAVLLVIGIIGTTWSGILVMPSLINFGLEKEAELNK
                     ENKLYQEKVNIDKLDIAVDNINVMIRKSSNEDVRVTTRGNNEFYKYSVTLQDKTLVVK
                     GERKSENKIKKIRSFDHLLNTSINSMFSRDYREIRIYVPNNVDINASSISSYLFISDD
                     VDSNNITYKTSSGGFSRAITENKVNRLENLNLISNSNLHLSTKSILGVKNVNIESESL
                     DISSENGDVFINNIEEYIPENVNIKEKIGRNSNYESEFYLYSDMPIAKFLDIEVPNSK
                     VRLDIPVNKYKFNCDIKSKEAIEEFNNDEEYDNDSYDYEHNEEHSNKYRNTREIKGLL
                     NKNLSNLEKEYTIKINSNSLEL"
     gene            complement(18941..19999)
                     /locus_tag="ACGI5H_002640"
     CDS             complement(18941..19999)
                     /locus_tag="ACGI5H_002640"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428198.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1700 domain-containing protein"
                     /protein_id="HFG9698338.1"
                     /translation="MNLNKTEFLEILKDYLKKDFSESEVNDILRDYEEYFVDGLIEGK
                     SDMEIIASLGSPKSIAKELILQTKEKNIEEEKIINTDVLNDKFSKFKSDMKKGYSILK
                     DEAKEKYSKSKENIDGKIMNTDILNGKFSRFKSNVKKDYSILKDEAKEKYNKSKENIN
                     DKLTPSIEEGVGGLSRQVIKGLLVVLSLFLIVPAFAFVCAIVSATIALVCSLIAFVIL
                     IPFVIKFIAMVPDVMMFCIFATIAFVGLEILAWQILLFAIKLGKQLLNNYIHWIKRKN
                     IYIKANEKMEKRKKATLNDEDLNKDINENSYNNDYYNREEESIKETDEYNDDSINFEA
                     IYKDLEDIENKKGEDKHE"
     gene            complement(19986..20318)
                     /locus_tag="ACGI5H_002641"
     CDS             complement(19986..20318)
                     /locus_tag="ACGI5H_002641"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905416.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PadR family transcriptional regulator"
                     /protein_id="HFG9698339.1"
                     /translation="MNTQFRKGVLEICVLALISKKDMYGYEIVHNISKVIDVNEGTIY
                     PILRRLTKDLYFETYILESNEGPARKYYRITSLGKENLSNLMEEWREFVKAVEILISE
                     DEGGNELE"
     gene            20517..21638
                     /locus_tag="ACGI5H_002642"
     CDS             20517..21638
                     /locus_tag="ACGI5H_002642"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438374.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016758 - hexosyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HFG9698340.1"
                     /translation="MKDDKTILILTAQFGAGHISAAKAVKECIIEKYSNYNVVIQNFI
                     NASIPMMNKPMVKLYENNTKYTPGLYNYYYYFKKSFDSRHDLSHKLYTPKLSEYIADI
                     NPDLIISTFPLAAACVNNFKIKNPDINIPTLTVITDVVDSMEWVFENTDLYFVPSPEI
                     KNRFFQKGINPDSIKVTGVPVDKRFQIESKELCCDKYRLLLLGGGRGLFDIDEDFMHW
                     IDEFIEEHSNSIEITIVTGKNKKLYDNLTHKKPLKNIKVLGFVNDMYNLIRECDLMLT
                     KPGGATIFEAIQSQTPVLVKMPKVGQEIENAKFIIDKGLGMIYSDDLDLKNIFYKLVS
                     NEFDSIINFMKKNLKEFKTVIHPEKIADYISELIDNHYS"
     gene            complement(21766..23664)
                     /locus_tag="ACGI5H_002643"
     CDS             complement(21766..23664)
                     /locus_tag="ACGI5H_002643"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine synthetase"
                     /protein_id="HFG9698341.1"
                     /translation="MDSLLYVIEKDKHTNEELREILKSNKNIRFVSLMGVDLGGNATD
                     EKIPVELFLEDIDKFLESAIQTDGSSVELYNIATLNNAKVDLMPDKSCHWYVDYNMEY
                     IDEEVGLPVGTLKIPAFLIHDNKKVCSRGVLQKADKYFKKSMYEIFREYPHVINNIGI
                     DSVDDIEEIMLTAATELEFWVNTPEDKADLEKLYVSQSLKEQYWKRTHGIIRTCLEKS
                     LIILQKLGVNPEMAHKEVGGIQSSISIDGRTNHAMEQLEVSWKFSTPLQAADNELLVR
                     DVIEDVFTSHGLEVTFKAKPIHGVAGSGGHTHVGVSAKLKDGSIKNLFAPKDLKEDYL
                     SELGYGALMGLLYNYEVLNPIVTASNDGFNRLVPGFEAPVCIVTSLGHSYEIPSRNRS
                     VLVGLIRDMKNPKTVRFELRSPSPLSNTYLVIAGCYQTMLDGIKAAAKSGLSTKELEK
                     ELSKNVGEESFYLEKDRAYRDENDVFEHYSLEERNARFGIPPATVYENMKNLEIYASK
                     LKSLKQGDVFTDSIIESFKIGAIDKWQKKLKTRIIEAGIQKIRSIVKIHTKENMDALD
                     EVVWNSISDLKFNIMKDTLTRESLFTRVREAIENKDYQTASDLQIELKRSMEEIQQLY
                     MQYKKNIY"
BASE COUNT         7760 a         4030 c         2586 g         9450 t
ORIGIN      
        1 acatttaatg taacagttcc tttttcaata acattaaact tatctaaatt ggcctctatc
       61 atatactttt tctttgtctt tttacttgct tctgtatatg cactcattat tgtgtcataa
      121 ccatttactc ctataaacat ctttgtatac ttgacattgg tctttgctat tgttccaact
      181 gaaagcctat tttcagcaaa tacttgcttt gctatgtctt caactaactt atctttaaaa
      241 ttgtatgaca cttcactttg tgtaagtaaa aatcccatat ctttagatac aaaactaatt
      301 tcattactgc ttgaatcttt agacctatta attatcattc ctctaaagag ttctttctca
      361 tctacataga aacagactgt actagctatt ggtatatcta tttgttggaa atttacatca
      421 aatgatgatt gtattattga aaactctagt gtccttgatg gagatttata atcacctgac
      481 catgatacct tgtctactat gtcagttatg tcatatatac ttccgttttt tatgtgtacc
      541 caaatcttaa taataaaaaa tcacctgcct tttcatttaa ttctataagc agttatttat
      601 aacttattat ctataatagt tattgttttg gagttacttt tggtatcttt attcttttat
      661 actcttttaa atctaatgta aaatatacat ctcgagtccc atctctttct tcataactaa
      721 acccttcaat tatgacttcc atatttatat ttgtttccgt aattgtaaat cttaatataa
      781 aaccttcctt catccatttt tctatcttat ttacacaatc atatggtgat ggaaaacctg
      841 tatagtcaca gaaagtatag tctttatttg gaaaaaaact tgatattgaa atgcttttaa
      901 gagctacacc accaaaagtt gctatttcac ctattttgag tatactagaa gagtttacag
      961 cagcttttcc attaatacta aaggaagatg gaaatactgg aaatctaaat ctatcttcag
     1021 cttgtctaag ccacatttcc attataagac accccctaac tgtgccaatt ggatacttgc
     1081 aactaatttt gatgttatct tttctatatc agcttcttct ctaatcacta ttgtatcagc
     1141 taacttagct atgtttatat ttccaccatt ttttctgctt ctatattgat ttgcttcttg
     1201 tttagttaaa accatttcac cttcatggag tctggtttga tagtcattat aaggaacata
     1261 gttcaatcca aatgcattat tacctttctt acctgaataa gctttaccag aatcaccagc
     1321 ctttgttcca gcatatggat tatctttgta atttttttta ctcttttcca ctagatttaa
     1381 aactgttcct gtgatgcttc cattttttat cttattaatc atagtttgcc accacttgca
     1441 tatatcttta actattttac atactttatc taatatgtta aaaaaagctc ccaatattgg
     1501 ctctataatt ttccatccag tttccaacag aggtcctaag gtctcccata cagttttcca
     1561 aataacaccc agtgtctcta taaaattgtt tatttgaggt gcatattcac ctaaaaaagt
     1621 aaaaattctt gtgataatag gactaacagc ttcaactaca ggtccgatta gttggaatgc
     1681 tgtagttact attgtaccaa atatacttat taatccttgt gcaattggtg atttattgtt
     1741 tatactatct agtaaattat ttactaagtt tactactgga agtaatgaat ctattaatgc
     1801 tgtaaaatcg atattttgta atagtgtact tcctgcgtta acaattgctt ttggtgcatt
     1861 ccctatcatt gttgctgcat gattttcaaa acgttcttgc ttattttcaa ccatcatttt
     1921 acgcttttca gcctcattag aaattcgata ttgagtagaa tcagaaaact cttttccatt
     1981 ttttacactt ctagattgca tctggtcata tttgttgcca ataattatct taccattcat
     2041 tacattgcct attttaccag ccattttttc agataagcca gctaaattgc ctaatccact
     2101 ttctataaaa gtttttattt tctttagtcc ttgacctaaa atatcatcaa aaggtttaac
     2161 aatactcttc aagccattgt taatgcttgt ttgagctcct gatattatac ctggtattgt
     2221 attactcatt tctttagcta accccatctg ctttacactt atgccttcca atgcttcatc
     2281 aaaagtttta taattttctc ctaccagagt attaagagat tccatgtttc cttttgctgc
     2341 acttaagaaa gctgctgata catcttgttc actacttgta ttcatattta aagctctaac
     2401 atctaccata gcttgagtta tatctttttc ttttttgcca ccagtaatat tactaatcat
     2461 tttagcttta gttcccattg caacaacatc ttcagggtca aaaggcgtat catttgccat
     2521 tcttactaaa ctgccataat aatcatcaac atctatttga ttaacttttc cagtatttct
     2581 tttcattaca ctttctagaa caactttctg attttgttcc tgaccaagta aatcaacacc
     2641 ctttttcaca gcgacaccta tagtagcacc atttgtcaaa tcagatatct tcccttttat
     2701 cgaaccaagt attccacttg ccatatcctt tacagctatt gcaccactcc ataccttacc
     2761 tgcaaataat ctcaatttgg gaaatacttt acttataatg ccacttgcca tatcttttat
     2821 agctattaca ccactccaaa aagtattttt aaacaacatt aacttaggca aaattctacc
     2881 catagcacta ctcaccatat ctttaagatt aatacttcct tgataaggac gtttctctac
     2941 ttgttttaat tttcccaaga tactacttat aactctctta gtcatatctt ttgcttttat
     3001 tacgatattc caaaccttgc caccaatctt ttttaaattt ccaagtaatt tatttttagt
     3061 tttttctact tcatcacttt tagctttaaa tattaatata atcataatat ttgaattaaa
     3121 ctcatttttc ttttgaatca acttattaaa ataatcaata atcatagcta tagttattgc
     3181 tagtatcata atacttccat ttaaacttcc aataactcct gaaacagcat ttatgctaga
     3241 acttaatttt gtcatagttg aacttacact actagcagta gtttgaactt ttcttaacga
     3301 ggaatttaaa ctgtttactc tattacttgc acttccaata gaatttttta tgctactagc
     3361 cattacatta gtggaaagtg aaacagccac agttgctctc ctaaaattat cagttactga
     3421 tataatttga ttcatttttg gtgtgtaatt atctgtaagg tacatattta taccttcttc
     3481 tctcacattt cccattacat accacctcct gtcaaaggac acactccata tccatgtttc
     3541 attttttcaa cttcttcctc aatttctaag gcgaaaaaag cttcaataag ctttaattcg
     3601 cctttatcca ttgcataaaa aagggacggt cttatacctt ttttcttcca ataatagtac
     3661 attattgtag tcctggtatc cgtccctatt agttttttac ctcttctatc actgcatttt
     3721 taccataacc cataacatct tgaagtattc tatataagtt ggtaatttca cctggtaata
     3781 ataattttct tgctaattct tttggtgttg gagccttaaa tttatccatt agctccttat
     3841 ttttaaataa aagctttcca tccaaatcac aaacaccttc tataattgta agcatctgca
     3901 tctccggtaa gtctatatcc gttttcatat tttcatcaat tttaagacaa gtattttgta
     3961 tttcttcatc tttacttatt gttaaagctc tacacattac tttaaattcc tgcccaaata
     4021 tagttgataa tctcttaagt tcaactatag tactcggtct ttctaagttt tctgtatctg
     4081 aatttaaaag taaatctact atgtttatat tttttgataa tccattttca ctcattatta
     4141 tttgctcctt tatcaatcaa attcaatcaa ctaacttttt tacttattaa ctatctgaat
     4201 ttattaagta tatatttact aaatatcagt ataaaaccaa atataaaact aaatataaaa
     4261 ctaaattata tcaagaaaat catactcagt aaatgtgaaa ggtgcttcta tctctccttt
     4321 tacgccaacc tcccaatcag ctaaagttaa atcatcaaat gctatattct ttactgctat
     4381 tctttctgct ccataagaat ctgggtcatt taatttagat atagcaacaa acctaggttc
     4441 agaacctctc tttatctttt ctccaattaa cttgtgcatt cttgaactaa cgtggtatag
     4501 agttattgag ccttttcctt tatatcctat atactttgta tcagtaccca tttgacctgc
     4561 tattataata tcttcttttg taaattccat ctttgcttga aatttcttta cttctgctac
     4621 tttgtttcca tcaagccaaa gttctcccca agtaccactc attacatttc tagcttccat
     4681 atttgccata ttaataatcc tcctatattt ctattgataa atctatatct tccatagcat
     4741 caagtacttt tatttttgct tttaaaaata ctttagaacc tgtgttagct tcttttattt
     4801 cttgtaatgt catataagat aaatctactc cttttgattt taaatacgat ttttgtgctt
     4861 caaaatctat ttcaacagta gaatcagatt ctataagtgc tgatttttct aattcttcta
     4921 aataactttt tatagctact atcaataaac atttgttgtc ataactgtta gtaacctttc
     4981 ctatatagtc atctattatc acctttctta tgtcactatg tataatatct aaagtgtcaa
     5041 ctatttttat tttctggaac atttctcctt tttctgctgt taattcagtt aaagaattta
     5101 ctcctctagc aattcttata gctcctgctt ctttaataag tataagctct cctttattaa
     5161 cctttgattc tgcatcaact ttcgtcatct taggtatatc gactacatca ctaagtttag
     5221 tataagttac tgattgactt aaaggtgtac ctgctataag tccagccacc ctacttgtaa
     5281 actcatcaac actgtatttc ttttctccaa ctaacacatc ttctgtagta aaattaatta
     5341 tcccttcatg atttcctaca acttttccta atacagcttt aaccttaacc ttatctatat
     5401 ctctaagttt aattatccaa ttttttatag cagtcttatc agcttctact gcttttggca
     5461 tacatagata attaaattcc ttagtctcta aaaaatctaa tgcagtttga atatctgctt
     5521 ctccttctat tacataaact aataacttat ttggagtgtt aacatttccc atcaaagcta
     5581 aatttatata ttctttattt tcagcagata aatcaactgg tatatcctct ttttcatgta
     5641 tttcattaag acctagtgcc ttagcatctt taagtaccat tgcaattatt cctctagctg
     5701 aacgttcttt aacagttgta gctagctcct taaatgatat gttgatactt ggtaatccta
     5761 tagccatact atcactctcc taaatttaaa ttgatttctt ccatattttc atatactaca
     5821 tcttcttcat atacactatc cagatagttt agtgtaaatg taaagttcaa tacataaatt
     5881 gactcttctt ttttaatact ttgttctagc tttgttatat ttaattttct gtctgttacc
     5941 tttatatttc tgttgaataa cttatttaat tcatctgaaa cttcatacat tctaatactc
     6001 tttgactgtg gttttggtaa gtattttata gagataacaa tatctttgtt attcgtattt
     6061 aacattacag gtgtacaaat aactgatagt atacttacaa aaaaacaaga cccttcagag
     6121 ccttgcacac tttcatcatc aataaaaata ctttcagtaa agtttttttt gagaatctca
     6181 ataattgttt ctaatatttc cttgtattta agcaaataat caccacacta tcactaaata
     6241 ttcttgctta atctgataat cttactataa atgatataag tcatttttaa atatatatct
     6301 catttattcc tgtcaagtat cttctatatt tttaggtaat attattcttt tcaatctatc
     6361 acctccttca atatggattt ctttcacaat aacattatct cacatatttt attgcctatt
     6421 gttgtaatgg tgtatataaa gtgttgtaaa attgtcctat tttttataat atctcactca
     6481 atttaaatat catctttttc tttaaattgt agcaagatgt tctatctaag tgtagtttca
     6541 tagaaatata tgtcatattg ttttttgtct tactattata aaaaagatta aaaaattcca
     6601 tttctatatc atttagacac gttagagcat tttctatctt ctctttttct atttctatat
     6661 cttctttttc catttttaat tttcttaatc tttcctctct ttttaacacc tcattttcca
     6721 cagaagagct tatgttatat gtgttactag tcttttctgt atataccatt gctccacatc
     6781 cagagtattc attctcacat ctttttatgt ccaagttaat attctttatc tttatatcca
     6841 aatacttata attatgtaat cttttatctg tttctttaaa taatatatct tttttgtttt
     6901 ccatagtact tccccttttt tatatactta ttattagctt caaatttaca ataatctctt
     6961 tagtgcacag ttttttacta atctcacaac cttcaagaac atattgttct ataactgtat
     7021 aaaaaaaact tcttctatat tttgttctaa aatactagaa atcttcttag ccataagaag
     7081 tccaggattt tttatgcctc tttctatttg agatatataa tcatttgtaa ttccagcctt
     7141 tctggcaagt tgaatttgtg tcataccttt gcattttcta taatatttca agttattttt
     7201 aaacattgtt ttatacctcc attactatta agaatatttt gttcttcctc acttagatta
     7261 tatagaatta tttgttcttt atcaatagat tttagaaaaa aatattcttt tatattttat
     7321 tagttttatt ttttagaaca atttgttata atctatacat aaggtggtgt tataatgttt
     7381 gccaaaagat taagagaact tagaaaggaa tttggattga ctcaaagaga acttggagaa
     7441 aaagtaggcg tttcccaaag agtcttaggg tactatgaaa cagaaaacag atttcctgat
     7501 gaacacattt taaataaatt ggctgatgta tttaatgtat cagttgatta ccttcttgga
     7561 agaaccttag ttaaggaaaa tattgataca gtagctgcac atagaaaaaa tccacatgaa
     7621 gagttacctg aagaagcaca agaacaactt aatgattata tagaattttt actaaataaa
     7681 tataaaaaaa aataaaccat atgatgagca gtctattttt ctgctctttt aatataattc
     7741 aaaggcaaac atacattcta ttttaggggg atttttatga ataatttgga taagcttttt
     7801 gaattagctt ctcaagaaga gataataatt cattatacca cttatattgc aggtgattta
     7861 gaaggactat atataaacaa acatggtatt aaaattatat cattactcag taatttaaaa
     7921 caaaactcaa aaaaattgac atccatctta gctgaagaac ttggacatca tttcactagc
     7981 cttggatact atgtatcctc ttataacgat tattatacaa aaattattat agataagtgc
     8041 gaaaataaag ccttaaaatg ggcttgtgag ttcttaatta ctgaagaaga tataataaac
     8101 ataattaact ctggcatcac ttgcgtttat gaaatggcag acatacttaa tgtggatatt
     8161 actttctttc aaaaaagatt agaatttcta tcattaaaaa aacagtcttt acaacttgga
     8221 aataataaat atttaatatt aactaatttg ccgtatttct acatatttga tccaatttca
     8281 taataaaaat agtagtaatt ttaactggct taacagtaaa atctatatat ttattttaac
     8341 aaattttggt ttctataaat tcaatattaa tatataataa tgatatcata ttatttaaaa
     8401 ttctaaaaac aaatatatgc ttttgttaag aaaggttgtt tgatgaatgt ataaagaaaa
     8461 gttgtttgat aattatttta agttcttagc actattattt tggccaatta tgtggtataa
     8521 gtggatagta atttcaaatg gtactcttga aaatatgtta tttaccatat atgcaatcgt
     8581 cgcaattgtt ttcatcattt tatattcggt gtttatgata aaatataaag acattacaca
     8641 aatagatttc ttttacagga taagtactct acttgctttt atatttacac tttttagctt
     8701 tttaatatac ccaaagagtt tatttttctt gtatttaaag attattttta ctggaatata
     8761 cctttattat tcaatagtaa aaactcttaa atttaaagat gacgaaggtg tagtgggtat
     8821 tatgagctca cttttattaa ttgtaataac tttgttctac taaatttaat tctatttgac
     8881 ttaatatggc tttaaatatt agacatctac attattttct gatattattt aagatggtag
     8941 tcttatatta ataatgaaat acactatgaa ggagttaact attatggaaa aaaaagtttt
     9001 agcaacagtt ggagaaaaag agataactaa tattgatatt gaaaatgcat taaaatcatt
     9061 agacccttat caagctatgc aatttaaaac tgaagaagga aaaaaacact tattaaatga
     9121 tttagtgaat caagaattat tcttcttaga tgctaaagaa gaaaaattag atgaagaaga
     9181 aatatttaaa ttagaaatga aaaagataga agaaaatgta ttaaagcaat ttgctataaa
     9241 taaagtttta tctagtgtta atgtaacaga agatgaaaaa gtaaaattct ttgaagctaa
     9301 taagagctct ttctctaaac cagaaagtgc aactgctaaa catatattag tagatagtga
     9361 tgaaaaagct aaagaaatac ttgctcaaat aaaatcagaa gaaatatctt ttgaagatgc
     9421 agctcttaaa cattcttctt gcccatctaa agatatgggt ggtgatttag gaacattcgg
     9481 tagaggacaa atggttcctg aatttgaaga agctgtgttc tctatggcta aaggtgaagt
     9541 aagtgaacca gttaaaactc aatttggata ccatataata aaattagaag accttcaaga
     9601 aagtacagag tctacatttg atgaagttaa ggctgaagtt gaaaaaagtt tattatatca
     9661 aaaacaaaat gaagtttatg gaaataagat aaatgctctt aatgctaagt acggaaacct
     9721 tgtaaaatac aacgattaat cataaggtca tatataaaaa agctgtcttt tcacaatatt
     9781 tattagaaaa gacagctttt tatattaaag tttaaatatt cagtttcata ttatcatttt
     9841 tttattgtaa agaactcagc ttaaaagttt aaataagatt tttaattatc attagctaaa
     9901 tttttatatc cacgtattat ctcataacag taacctatta catctcttct ttttattatc
     9961 ccaataaatg tgtcttggtc atctataaca ggaatgaaat tttgatttaa agattttata
    10021 actaaatctt caatatctgc gttgatggaa acaggagaat tatccatttt tctatttata
    10081 tctgtcactg gaacatcttc caatcccttt aagtccagat ttaaatcatt ttttaatgtc
    10141 cataaaaaat caccttctgt tatagttcca acatatttac catccttact tattattgga
    10201 attgcagagt atttgtgata ttccattttt tctagggctt gccttatagt gtagtcttca
    10261 tatatatatg ctacttcact ttttggtgtt agaaagaata atatgttcat tacactaccc
    10321 accgttactg aaaacttata aatattactc aatatttata atgttacttt tttgcagtaa
    10381 ctttctcctt tcttattttc taagtattct taatactata cgctgtaaca agcgtttttc
    10441 ctttgctcat tttaatctta ttatgcttta ttaatatttt tatatggtct ataagtatca
    10501 cttattctct ttttagaaaa tttactaaaa attaattgac ttaaacttag ccataataat
    10561 tttactctac actattaatt ttaacatatt tatctcatta ttaatgattt tattttaata
    10621 attttaattt attttgctat taattttatt tacaaaaact gaaaaaaccg ctaaatgatt
    10681 agcggcttat ctctcatatt actagaacac taatatatat gaatttttaa ttataatcta
    10741 actacgttag cagcttgagg acctttagct ccatctacta cttcgaactc aacgctttgt
    10801 ccttcttcta atgttttgta tccatctcca gttatagctg agaaatgtac gaaaacatct
    10861 ccttcacctt ctacagatat gaatccaaat cctttttcgt tgttaaacca tttaactaca
    10921 ccagttttca ttaataaatc ctcctaaaaa aacacaaata tttagctact cttttctgta
    10981 accttattac tactctatca tatatagcta tgtttgtcaa ttattattat ttttatacat
    11041 taataatcaa tttttttact ttataatttt aaatgattat tatcttttac actttatttt
    11101 tctttataat tttttaataa tttattttta ttatatggaa tcttatggac ttatcactcc
    11161 agcctaaatc ccatggcacc aacattctat cagtattatg gcaagttacc aaaggatatc
    11221 ctcttgagtc taatcctgtc actgtcgaaa catgtgttat tctgcctttc ttctcataac
    11281 caacaaaatc ccctggacgt aaattataag cttctttgta tacttcttca taggaacctt
    11341 tagcaattaa tgaacctctt ccactataca gtgcataatt tttaaaagct tgtgcattta
    11401 cccatgcttt tgtacctgct ctctcgctat aattccaaat tgagttcttt ttgaaccttc
    11461 cactttcaaa cattatctgt gatgcaaagt ttgcacaatc tccaccttct ggattataat
    11521 ccctatagtt tggattaaat ttcataccat gttcttcatc agctgcggct ccacagtatt
    11581 tatgtgcata atctatagct tttttttgtt catctgtaag ctgtaactct acaccatctt
    11641 gttgaccaat ataatttctt atatcatcag attttatatt ttctaaattt aaagagtctg
    11701 caaaagggtc tgtataccac tctttagtta tgacatattg attatctata atttttacat
    11761 ttagataatg atatgtacct attctaaagg cattttcttt gtccttttga ttttcatatg
    11821 aatacttata ttcagtggat actgaacaga ttataccata gaggtctttt tctttttcct
    11881 ttattttttt aatcttaacc cttgtcttta tgtctttaaa ttttacacct tgtttactag
    11941 accagttttc taaatatttc atctttttta cttcattttc ataagcccac agaccaaatt
    12001 ttttatccgt ttcataaaga ccttttaaaa tattttcatt tttctctaat attgccttat
    12061 ttctgtagtc aaataagttt tcaagcaata gtttatattg gtcttttaca tcatcacctt
    12121 caacatttgc agattccatg actttttctt ccatattttt catacttaaa tcattgatta
    12181 aaaatacacc tgctgtagta gctaaagaca aaaatacaaa tgccattata cctttgatgt
    12241 acttattctt atttttcagt attttcaaag ctacacctcc caaatagtac accttacaaa
    12301 tcaaattaca aagaatattc tgtcacatat agtaattttc atatttaata attctctatt
    12361 ttattatgtc caatattaaa aattaattgt atcaatacac tgtttttttt acaatttttt
    12421 attttataat ctactttttt ctttttttta tagtaatata tatgtatata aatattttgg
    12481 tatcattata attaatacat actaatggag ggttttttat gcaaaaaaaa gtcgcagcaa
    12541 ttaatgactt atctggaata ggaaaatgct cattatcggt tgctatacct atactttcag
    12601 cattaaaggt tcaatgttgt ccatttccaa cggccatact ttcaagtcaa actggttatc
    12661 ctgaatttac tttcttagac tttactgatg aaatggtaaa atattcaaat gtttggaaaa
    12721 atttaaaagt caattttgat agtatatata gtggtttttt gggttcaaag catcaaattg
    12781 agatagtggc taattttata aacgattatc ccaatgcttt tatcgtagtt gaccctgtga
    12841 tgggtgataa tggagttatg tatccaatat tcacagaaga aatgagacag gaaattaaag
    12901 aattagttaa acattcagat ttaactactc ctaatttaac agaagcttgt ttcttaactg
    12961 gaaatgatta taccaaaagc gattataata gagatgagct tatatatatt gcaaaatctg
    13021 tatctgattt gggacctagc aaagtcgtta ttactggtat attagaagat gataatatat
    13081 taaatttggc ttacaataga gataatgacc atgtattctt tacatcagtc aaatataata
    13141 attgttctta cagtggaact ggagatatat tcacatctat actttgtggt atgttagtaa
    13201 ataaacatga tttgggagta gcggttaata ctgcaacaga ttttatatat aaaactataa
    13261 attacacatc tcaatttgat actgatagaa atgatggagt tatgtttgaa aactttttat
    13321 cagatttaac caatatataa aatcaaaaaa actatccatt ttataaatac ctataaatca
    13381 taaaatttag gtatttacaa aatggatatt atttactaaa ctattggtat ttcaattgtt
    13441 accatagcac caccagtttt cacagaattt tcaatacata aagtcccatt atgtttttgt
    13501 acaatattat ttacaatata gagtcccatt ccataatgag atttagaatt tctactcaaa
    13561 tctcctgtat aaaactgttc tgtagctttt gacaaatctg ctttagaaaa accacttcca
    13621 caatctgtaa ctacaaattt taagtattta ttatgtactg atacacttat gtatagttta
    13681 ctctggcttg gtgaataatc tatagcattt gaaattatat tcataatagc tctgaataac
    13741 agttctctat ctatagttat atttttaggc aaattatctt gtttataaaa ctccacatct
    13801 aagtttttag tactagctaa tgcttctatt tgcactaaaa catcttttat aaactcactc
    13861 atactgattg cttctttatt taatatatag ccattctctg tttttgatat atctattaaa
    13921 gtattaatat atttttctat ttgagtgaca ccctttgaga tatattccat gtattctaat
    13981 aactcaggat tttcatttat ttcaattaat aagtcagtat ttccatgtat aattgttagt
    14041 ggtgttttta tatcatgtgc cagtgcagat atctgttcct ttctattttc ttctagcatc
    14101 catcgttttt ctaaagaatc ttttaacgcc aacttcattt tatccataga aaaaaggaca
    14161 ttattaattt cataaatttt actagattct acaacaaaat ctaaatcctg ttgttctatt
    14221 ttttctgtag tattttttaa aagctccatt tcaatattaa atttcttgcc aaatactttt
    14281 gataatataa caatttcaat aaaaaatatt atactaaaaa taatcatacc caatgtctct
    14341 ggttttggta aatatgctct taaaattgga gaactatact ctgatactat tttgtatttt
    14401 attataaaaa cttcatcttt cttaaaaaac tttatataac tttctgaata tgcatgcctt
    14461 tcttcaatat ctctcattaa attccatact tcttttgatt cttttttatt aaaggtccct
    14521 gaaattaaat tcccatccaa agtataaacc ccatactcat atatacttgg aattatatct
    14581 tcagttactt tttcacttga aataatctgt tctttatatt tattaaattg tttttctgca
    14641 taattagctg gtaaaattac acctgatgat aataatacag aaaatgataa cattaaaagg
    14701 agtacaattg aaattgtcat aataaagaat aaagataaat attttataaa aatagttctt
    14761 aacttttcaa cttttttgtt gttagatttt ttacctccaa gcatttgtac cctgtcctcc
    14821 aatagtttaa ttaattcata attaataccc aaccagtttt ttatttgatt attttatatc
    14881 tttttattgc taagttatat tttaacataa taatataaat aaacagtcaa tttttactct
    14941 attcttctga ttttttacct tcccatttag aaaaccaaat acataaaatt acaaatgcta
    15001 aaattgttac aaaaccacaa attaaacctg ttgattgata tgcttttatt gattcaacct
    15061 ttatatattc aaccgtttta gaacttgaaa aagacgacca aatagttata aatctaacac
    15121 cccatgcaca aggaaaatac tgccaaatac cagaacccaa tccagttaat aataatgctg
    15181 aaagtaacat ttcaactata cctactccaa ttgatgttcc ttttccgaac cttaaactta
    15241 agaataaatg taatatgtat tcaaataaat tacacccaat taaaattaga attgaaatca
    15301 tataaaagct tgatgtaaag taagccttag atataccaaa tttaaaacct aatacagaca
    15361 ctaatgttgc tacaaaacca agacatacta agattatata tttacttata agagtaagat
    15421 attttggatt agatgttgtt aacatatgtt tataattccc tgcataatat tcttgttcaa
    15481 caaacattga acacacaaca cttgacaata aaggaaaagc tattgctata acttgtaaat
    15541 atgctactat ctttagtata ttatcagctc ctgaaacctt ataataccat aaaaacaatc
    15601 ccatccccat taaagcaatg caaatgtgca ttagtattat aaaatttctc tttaatttta
    15661 ttaaatcaga acaaaatatt cttattaact gtctcatatt acttcacctc tctattattg
    15721 aaccaaaccc ttgtagctaa agcaaataat acaaataaaa caatagatat taatactcct
    15781 ggcaaaataa cagcattatt taaaaattca cttccctctg gtacaggaag accatttggc
    15841 agaatatgca atacaacagc cattaatctt gaaggaatcg aatatggaaa catataccac
    15901 atttctgtag ttgagaaaac agcaactcca acaatagtaa agaacatatt tgttagaact
    15961 gtaacaaaca taccaaattt tgaagctaaa aacatacaaa gaggaatctg ccacataaat
    16021 agtaaaataa ttaatatact tgcaatgata ttttgaccta ttgaaatagt ttctttatag
    16081 attatcccaa caaaaactac acctattgca gaaataattg atgctataaa acaacaaata
    16141 atacagtaaa tcatttttcc agtccaaacg tctttcattt caattggcaa tggtaaaata
    16201 ccacgatatt tacttttttc atcttttaat actattaaag aagatattaa tgttaatgct
    16261 cctggaagaa atgtcgtata ccaccagttg aaagcagcat tttgccctcc acctagtcca
    16321 cacaaaagta tacaaaacac tggaactatc catatcaact tcattccaaa agttcctttc
    16381 atcttttgaa attccactct aataaatctt tccatattac tgccctctct ttctattttc
    16441 agctacaact ttcataaaaa gttcttctaa gttttgttct tttgatactt ctccttgata
    16501 acccattact ccattagaaa ttattcctat ttcatctaca acttgttcaa cttcagacaa
    16561 gatatggctt gataaaataa ctgtaattcc ttgttttgga aaagaacgaa tcaattctct
    16621 aagttcttca ataccaatag ggtcaagacc atttgtaggc tcatctaaga ttaaaagttt
    16681 tgggtgattt aataatgcaa tagcaatacc aaggcgttgc ttcatgccta gagagaattg
    16741 acctgaacgc tttttaaagg tatctcttaa atctacagtc tctaaaactt cttcaatgcg
    16801 agagtcagga agaccaagta aagtagtatg gacttttaaa ttttctcgtg ctgttaaatt
    16861 ctcatatata gcaggagact caataagaga accaatattt gataaatcct ttctagtcca
    16921 tctatgtccc tcaaacatta tttttcctga agttggattt aaaatcccag ttatcatttt
    16981 taataaagta gatttcccag ctccatttgg tcctaataat ccatatatag aattagattt
    17041 aattgctagt gaaatgttat caactgccat ctgctcctta aattttttag aaactccttt
    17101 tacctgcaaa atataattac tcataatttt catcctttct tttgtcaaac ttatttacaa
    17161 gaatcattct aaatcataaa tataaggatt ttataagaat taaaaaacaa aaaaagatgt
    17221 gttaaaaaca catctttttt tatcttaatt ctattaattt tccattgtag tatatctcta
    17281 cttcttcaat ccaaatgcta ttatcttctt cttggatgac atttttaata atattattta
    17341 tagtatatat tatattttgt tcattcaaat aatcatcttt ccaagaaact ctactttttt
    17401 tatctggttc tatcaagttt attttaacaa gattatcttt ttccttaact tctacttcca
    17461 tgtctaaacc attaaaatac tcatttgata atgtatctaa gattaatcgc agtttatcct
    17521 taagtgaact ttcttcatca atctgtaagt actttactat tttctcatcc tttgaaatta
    17581 tctctatagg tattttagta gtttttttag aattaatcat tttactagtt gtttcttctt
    17641 ttgcatcttc atccttcttt acaactgctg attctttaga atcaactagc tcaactgcac
    17701 tgatgctata atccatacat gccgtactca ataaagtagt agcaattatt aaaaaactta
    17761 ctgctatttt attcataagt atccctctcc taattctctt tcgatactta ttataccata
    17821 gtatagatta tatttttata cttttaaatc aatttataaa ttattatagt aaattattta
    17881 caattctaag ctatttgaat ttatttttat agtatattct ttctctaaat tcgacagatt
    17941 tttattcaaa agccctttta tttccctcgt atttctatac ttgttgctat gttcttcatt
    18001 atgttcataa tcatatgaat cattgtcata ttcttcatca ttattaaatt cttcaattgc
    18061 ttcttttgac tttatatcac aattaaattt atacttattt actggtatat caagtcttac
    18121 cttagaattt ggaacttcta tgtccaggaa cttagcaatt ggcatatcag agtacaagta
    18181 aaattcactt tcataatttg aatttctacc tattttctct tttatattta cattttcagg
    18241 tatatactct tctatattat tgataaatac atctccattc tctgaagata tatccaatga
    18301 ctctgattct atgtttacat ttttaacgcc taaaattgac tttgttgata gatgaagatt
    18361 gctattagat attaagttta agttttctaa tctatttact ttattttctg ttatagctct
    18421 gctaaaacct ccagaagaag ttttatatgt tatattattt gaatctacat catcagatat
    18481 aaataagtac gaacttatac ttgatgcatt tatatctaca ttatttggta catatattct
    18541 aatttctcta taatcacgtg aaaacatact atttatagat gtatttaata agtggtcgaa
    18601 acttctaatc tttttaattt tattttcaga ttttctttcg ccttttacaa ctaaagtctt
    18661 atcttgtagg gttacactgt atttgtaaaa ttcattattc cctcttgttg tcacacgcac
    18721 atcttcattt gaactttttc ttatcataac atttatattg tcaacagcta tatctaactt
    18781 gtcaatattt actttttctt gataaagttt gttttctttg tttaattcag cttccttttc
    18841 taaaccaaag tttattaggc ttggcataac taaaatccct gaccatgttg tccctattat
    18901 acctattacc aataaaactg cagcaaatat agcaagtttt ttattcatgt ttatcttctc
    18961 ctttcttatt ttctatatct tcaaggtcct tatatatcgc ctcaaaattt atactatcat
    19021 cattatattc atcagtttct tttatgcttt cttcttctct attgtagtaa tcattattat
    19081 atgaattttc attaatgtct ttattcaaat cttcatcatt taaagtagct ttttttcttt
    19141 tttccatctt ttcatttgcc tttatataaa tattttttct ctttatccaa tgtatataat
    19201 tatttagtaa ttgtttacct agttttatgg caaataataa aatttgccat gcaagtatct
    19261 caagccctac aaatgctatg gttgcgaaaa tacaaaacat cataacatct ggaaccattg
    19321 ctataaattt aatcacaaat ggaattaata taacaaaagc aattaatgag catactaatg
    19381 caatagtagc agatacaata gcacatacaa acgcaaatgc tggaacaatt agaaataaag
    19441 ataacactac taataacccc tttataactt gtctggataa tcctcctaca ccttcttcta
    19501 tacttggtgt aagtttatca tttatatttt cttttgattt attgtacttt tccttagctt
    19561 catctttcaa gatagaataa tcctttttta catttgattt aaatctacta aatttaccat
    19621 ttaatatgtc tgtattcatt atttttccat ctatattttc ttttgattta ctatactttt
    19681 cttttgcttc atcttttaag atagagtaac cttttttcat atctgattta aatttactaa
    19741 acttatcatt caaaacatct gtatttatta ttttttcctc ttcaatattt ttttctttag
    19801 tttgtaagat aagttctttt gctatagatt ttggtgagcc aagtgatgct attatctcca
    19861 tatcactctt tccctctata agaccatcta cgaaatactc ttcataatct ctcaatatat
    19921 cattaacttc gctctcagaa aaatcttttt ttagataatc ctttaaaatt tcaagaaact
    19981 cagttttatt caagttcatt acctccctca tcttcactta ttaaaatctc aacagccttt
    20041 acaaattctc tccactcttc catcagattg gataaattct cttttcctag tgaagttatt
    20101 ctatagtatt ttctagcagg accttcatta gattctagta tatatgtttc gaaatacaaa
    20161 tcttttgtaa gtcttcttag aataggatat attgttcctt catttacatc tattacttta
    20221 gagatgttat gtactatctc atatccatac atatctttct tagatatgag agcaagtaca
    20281 caaatttcta aaacaccctt tctaaattgt gtgttcatat actccatcct ttctttaaat
    20341 acacagtatt gtgttttaca aggtactatg ttaaaacttc ttatatcctc ataataacac
    20401 agtactatgt tctgcacaat agttattttt aaatattctt gttgattaaa tccttctata
    20461 aatgtataat actctaatca gatatatttt atgaaagtgg tgataaattg gctaaaatga
    20521 aagatgataa aacaatatta atcctaactg ctcaatttgg tgctggacat ataagtgctg
    20581 caaaagcagt caaagaatgt attattgaaa aatatagtaa ctataatgtt gttatacaaa
    20641 actttataaa tgcaagtatt cccatgatga ataagcctat ggtaaaactt tatgaaaaca
    20701 atacaaaata tactcctgga ttatataatt actattatta ctttaagaaa tcgtttgatt
    20761 caagacatga tttatctcat aaattatata cacctaaact ttctgagtat attgctgata
    20821 taaatccaga tttgattatc tctacatttc cactagctgc tgcttgtgta aataacttta
    20881 agataaaaaa tcctgatata aatataccta cacttacagt tataacagat gttgtagata
    20941 gtatggaatg ggtttttgaa aatacagatt tgtattttgt tccttctcct gaaataaaaa
    21001 atagattttt tcagaaagga ataaatccag actccataaa ggttactgga gttcctgttg
    21061 ataagagatt tcaaattgaa agtaaagaac tatgttgtga taaatataga ctattacttc
    21121 taggtggagg aagaggtcta tttgatatag atgaggattt tatgcattgg atagatgaat
    21181 ttattgaaga acatagtaat tctatagaaa ttacaatagt tactggtaaa aacaaaaaat
    21241 tatatgacaa tctaactcat aaaaaacctc taaaaaatat taaagtactt ggatttgtaa
    21301 acgacatgta taatctaata agagaatgtg acctaatgct aactaagcct ggaggagcaa
    21361 ctatatttga agctattcaa tcacaaactc cagtactcgt aaaaatgcca aaagttggac
    21421 aagaaattga aaacgctaaa tttataatag ataagggtct tggcatgatt tatagtgatg
    21481 acctagacct taaaaacata ttttataaat tagtatcaaa tgaatttgat tctataataa
    21541 actttatgaa aaaaaattta aaagaattta aaacagtcat tcatccagag aaaattgctg
    21601 attatatatc agaattaata gataatcatt acagttaaat tgtactatta aaaaatttca
    21661 aacataaaat taaaggcaat caagtatgct tttacacttg agaatttact catagtgttt
    21721 aataatactt gattgccttt atcatatcaa aatcaaattg ttatattagt atatattttt
    21781 cttgtactgc atatacagtt gttgtatttc ttccatactt ctctttaatt ctatttgtaa
    21841 atctgaagca gtctggtaat ccttattttc tatagcttct ctcactctag tgaatagtga
    21901 ttctctagtt aaagtatcct tcataatatt gaactttaaa tccgatattg agttccaaac
    21961 tacctcatca agcgcatcca tattttcttt tgtgtgtatc ttgacaatac ttcttatttt
    22021 ttgaatccca gcctctatta ttctagtttt taatttcttt tgccacttat ctatagctcc
    22081 aatcttaaat gattctatta tactatcagt aaatacatca ccttgtttta aagattttaa
    22141 ttttgaagca tatatttcta agtttttcat attttcataa actgtagccg gtggtattcc
    22201 aaatcttgca tttctttctt ccaaactata atgttcaaat acatcatttt catctctata
    22261 tgctctatct ttttctaaat agaaactttc ttcacctaca tttttagata actctttttc
    22321 aagttctttt gtactaagac cactcttagc tgctgctttt ataccatcca acattgtttg
    22381 ataacatcct gctattacta aatacgtgtt agatagaggg cttggtgacc ttaactcaaa
    22441 tcttacagtc tttggatttt tcatatctct tattaatcca acaagcactg acctatttct
    22501 tgatggaatc tcataactat gacctaaaga tgtaactatg catacaggag cttcaaatcc
    22561 aggaactaat ctattaaatc catcattaga agctgttaca attgggttta atacttcata
    22621 attgtaaaga agtcccataa gagccccata tcctagttca cttagataat cttcttttaa
    22681 atcttttggc gcaaatagat tttttatact tccatccttt aacttcgcac ttactcctac
    22741 atgtgtatgt ccaccacttc ctgctactcc atgaattggt tttgctttaa atgtaacttc
    22801 tagtccatgt gatgtaaata catcctctat aacatctctt actaataatt cattgtctgc
    22861 tgcttgtaac ggtgtagaaa acttccaaga aacctctaat tgctccatag catggtttgt
    22921 tcttccatct atactaatag aactttgtat tcctccgacc tctttgtgag ccatttcagg
    22981 gtttacacct agcttttgaa gtataattaa acttttctct aaacaagttc ttataatacc
    23041 atgagttctt ttccagtatt gctcttttag gctttgtgat acatataatt tctctaagtc
    23101 agctttatcc tcaggagtat taacccagaa ctcaagttct gtagctgctg ttaacattat
    23161 ttcctctata tcatctactg aatctattcc tatgttattt attacatgtg gatattctct
    23221 aaatatttca tacattgact ttttaaagta cttatctgct ttttgaagta ctcctctaga
    23281 acatactttt ttattatcat gtattaaaaa tgcaggtatc tttaatgttc caacaggtag
    23341 acctacttct tcgtctatat attccatatt gtaatctaca taccaatgac aacttttatc
    23401 tggcattaaa tctactttcg cattatttaa tgtagctata ttataaagct caacacttga
    23461 accatcagtc tgtatagctg attccaaaaa tttatctata tcctccaaaa ataattctac
    23521 aggaatcttt tcatctgttg catttcctcc taaatcaacc cccattaagg aaacaaatct
    23581 tatattttta ttgcttttta ggatttctct taattcttca ttagtgtgtt tatctttctc
    23641 tattacgtat aatagactat ccatttttcc actctcccat aatttttatg tatattttat
    23701 tttgttaaat acaagataaa tttcattttc cttacattta tgaatttttc ttgcaaatta
    23761 ttcgtgtttt attcgtgttt ttatttatat tattatatat caagtataaa aagttcgcaa
    23821 tatttt
//
LOCUS       DAYAOO010000062        23776 bp    DNA     linear   BCT 12-OCT-2024
DEFINITION  TPA_asm: Clostridioides difficile isolate ST8-SSI-h139-18
            SAMN40601845-rid21577343.denovo.062, whole genome shotgun sequence.
ACCESSION   DAYAOO010000062 DAYAOO010000000
VERSION     DAYAOO010000062.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN40601845
            Sequence Read Archive: SRR28438827
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 23776)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 23776)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-MAY-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-MAY-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002157583.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002157583.1
            Genome Coverage       :: 163x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/11/2024 16:19:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 4,038
            CDSs (total)                      :: 3,963
            Genes (coding)                    :: 3,930
            CDSs (with protein)               :: 3,930
            Genes (RNA)                       :: 75
            rRNAs                             :: 6, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 60
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 33
            CDSs (without protein)            :: 33
            Pseudo Genes (ambiguous residues) :: 0 of 33
            Pseudo Genes (frameshifted)       :: 7 of 33
            Pseudo Genes (incomplete)         :: 25 of 33
            Pseudo Genes (internal stop)      :: 11 of 33
            Pseudo Genes (multiple problems)  :: 8 of 33
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..23776
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN40601845-rid21577343.denovo.062"
                     /isolate="ST8-SSI-h139-18"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Denmark"
                     /collection_date="2018"
                     /collected_by="Statens Serum Institute"
     gene            236..1210
                     /locus_tag="ACGI5H_002644"
     CDS             236..1210
                     /locus_tag="ACGI5H_002644"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009906205.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aromatic acid exporter family protein"
                     /protein_id="HFG9698342.1"
                     /translation="MNNINSLKVIKLSLGCSLAIFIAWLLKLEYSMVAGVIVLLTVKD
                     TKRETLKGSIGKIYGFLLCTIFSYLCFNILGYNLTSFSIFIFIIIPLCFLLNIQDVIA
                     MCVVIASHYYLQGETSIKWILNEAGIFAVGTGIGVLINMYIPTNIHKIHEVQKKLQEE
                     VSIVLIDIADIIVNPKKENGYSRDLYTLNSLIDSSISETYDNINNTLLSDTRFFLEHM
                     DIIKSQRDILENLYSYVSQLNSTPPQAHILSAFIHKIGYTEFEAETGNLLLEELKRLM
                     LSMKNQPLPVDRTEFENRAILFLCLTELKQFLVNRKHAQMLRDNNFYK"
     gene            complement(1326..2387)
                     /locus_tag="ACGI5H_002645"
     CDS             complement(1326..2387)
                     /locus_tag="ACGI5H_002645"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861792.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transglutaminase domain-containing protein"
                     /protein_id="HFG9698343.1"
                     /translation="MKKIRKLATKLLITTIVLISGMSMTVYGMTAKEVTAKTPKSYVT
                     GTNSVYGPKLSQAQLNSVAQATADFMNKKITKNMTTDAKILVAYNHIKNNTTYVDWNA
                     VEGANTAYTLVTKKGACSGMARSMKALCDAMGIESYYVHSTSNDHQWNLIRFGDGRLY
                     HVDIDANKSAGKDIIYKSLSHPLPFDKTAYPKVGAIVQTVKPEQTQKPAPPGKHTMLP
                     HQEGAKAVGNFGKKGEDINEKHVMYEGVRCSVVNSSVNTITFTGSESNLDPSNLTIAV
                     IGFMNTPYGMFALAPEGKPVEYPFKYDKPFSLDFSGKNRSGAELAKYCKKNDVTIKIE
                     ITDEKANIGLGQIMYVRYE"
     gene            complement(2999..3850)
                     /locus_tag="ACGI5H_002646"
     CDS             complement(2999..3850)
                     /locus_tag="ACGI5H_002646"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439904.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MurR/RpiR family transcriptional regulator"
                     /protein_id="HFG9698344.1"
                     /translation="MSCILKLKQIYEDLTEVDKKIADYILNNTEAISKLSVSELASNS
                     KTSTASIVRFSRKMGYSGFGDLKIEIAKDLMGKENEYTYVDENYDCNIDSVINKITNK
                     NIETINQTRLLNEKDIIKEAVEQIIKAKNVYIFGVGGSALVALDLQMKLLRINKQAFT
                     SLDSHTQLMVSSNVDKEDIAIAISYSGESKEVIKSIENAKLKGCKVICITKYSDNHLS
                     KISDLKLVVPNIEKRLREGAISSRIAMLTLIDIIYISIIQENLNEAEQKLQETKRILD
                     YLNINNA"
     gene            complement(3867..4787)
                     /locus_tag="ACGI5H_002647"
     CDS             complement(3867..4787)
                     /locus_tag="ACGI5H_002647"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891357.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylglucosamine kinase"
                     /protein_id="HFG9698345.1"
                     /translation="MYFLGVDGGGTKTTFTLVDEELNIVGTITKGTCHYNQIGFDNLT
                     KLLITGLEEVCKDAKINVEEITYAFVGLAGYGKIKEVLYALEVATKNAYSHINYTLGN
                     DVEIALAGSLNGEKGINIIAGTGSIAQALDKDGNLHRCGGWGYVLGDEGSAYYIGMAT
                     LKMFTMQSDGRCSKTKLYDLIKRHLNIENDYDIIKYVNDEIKGDRIEIAKFATICLKA
                     VIEGDNTASKIFDDAAYELSRLIIGLEHHFEQGTKIKVSYSGGVFKSGDLILEPLKKY
                     LNKTRFGIVRPVLTPDLGACLLAKKKYYSK"
     gene            complement(4897..5811)
                     /gene="murQ"
                     /locus_tag="ACGI5H_002648"
     CDS             complement(4897..5811)
                     /gene="murQ"
                     /locus_tag="ACGI5H_002648"
                     /EC_number="4.2.1.126"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891358.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016835 - carbon-oxygen lyase activity
                     [Evidence IEA];
                     GO_process: GO:0009254 - peptidoglycan turnover [Evidence
                     IEA];
                     GO_process: GO:0046348 - amino sugar catabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramic acid 6-phosphate etherase"
                     /protein_id="HFG9698346.1"
                     /translation="MLIKTLENLVTEGRNKNTLQIDKEDTLGIIELINNEDKTVAYAV
                     EEQKESIAKAVNIIVDRMKQGGRLFYIGAGTSGRIGILDATECPPTYGVDFELVQAII
                     AGGNQAIFKAIEGAEDDKELGKQDIIDRGVTSKDVICGIAASGRTPYVIGAMEYAKEL
                     GCAVLSITMNPNSEMSKKADLPINIIVGAEVIMGSTRMKSGTAQKMVCNMLTTASMVK
                     MGKVYSNLMVDVKTSNEKLVERAKRIIMIATNVKYDVAEKFLEEADNSVKLAIFMIKS
                     GLDKDSAKSILDRQEGYISEALKSIEKL"
     gene            complement(5910..7007)
                     /locus_tag="ACGI5H_002649"
     CDS             complement(5910..7007)
                     /locus_tag="ACGI5H_002649"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MupG family TIM beta-alpha barrel fold protein"
                     /protein_id="HFG9698347.1"
                     /translation="MGRLGISIYPEKTTSKEIYDYIDKAAENGFTRIFSCLLSVKDTK
                     ENIIKKFKSINEYAKFKGFEVILDVNPRVFGELEISYKDLNFFKKTKADGIRLDMGFT
                     GSEEALMTFNPQNLKIEINMSNNTNYIDTIMDYQPNKENLIGCHNFYPHRYSGLNLEH
                     FIKCTERFNKYGLRTAVFVTSQNETTFGPWPVTDGLPTIEMHRNLPIDIQVKHIIAMN
                     NINDIIISNCYPTYEELKVLGSMRKDMVTFDVAIEENIREVEKKILFEEIHFNRGDIS
                     DSLIRSTQSRVKYKGYKFELFNTPKIIKRGDIVIESSEYGHYAGELQIALTDMKNSGK
                     SNVVGYIRKEELFILDYIKPWQKFNFKPSTK"
     gene            complement(7240..8586)
                     /locus_tag="ACGI5H_002650"
     CDS             complement(7240..8586)
                     /locus_tag="ACGI5H_002650"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003431385.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0016773 - phosphotransferase activity,
                     alcohol group as acceptor [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HFG9698348.1"
                     /translation="MLDKFTEFLDTKLSTSMARLAEQRHLRAVRDGIVASLPLIIVGS
                     FFLILAFPPLPDSWGVTQYLKENAVTILLPYRMTFFIISVYSTFGIGYSLAKSYKLDG
                     LTGGLLATATFLLTIVPTAIEGLTPDLLKIVEKSPELLAWYNSIPQGWQMPMANLGGG
                     SMFVAIVTSIIGVEIYRFTDKSKFKITMPEAVPASVTRSFEALTPAALIIILMAIVTY
                     FLGFDWHGFIAKLVTPLVSATDTLPSVIILIFLITFFWSFGIHGVSIIGSLARPLWIQ
                     LLDANTASYAAGQAVPGIAAEPFFQWFIWIGGSGATIGLALLLAFRAKSAYGKSLGKA
                     TVIPAIFNINEPIIFGAPIVLNPILIIPFVVAPIVMATVSWFAMSANLVSRVVVTAPW
                     TLPGPVGAYLATGGDWRASVLNLLCIAISIIIYYPFVKMYDKRLLHEEKVEEQEAY"
     gene            complement(8675..8983)
                     /locus_tag="ACGI5H_002651"
     CDS             complement(8675..8983)
                     /locus_tag="ACGI5H_002651"
                     /EC_number="2.7.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891360.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HFG9698349.1"
                     /translation="MRVLFVCSSGMSSAIAVNALQKEGAKNGIDIDVLAVGTQEFEDE
                     VKNGWDIAMVAPQVRHRFDYLKAFADEVSVPCALIQAQAYSPLGGPKLLKQVQELLSK
                     "
     gene            complement(9246..9644)
                     /locus_tag="ACGI5H_002652"
     CDS             complement(9246..9644)
                     /locus_tag="ACGI5H_002652"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422533.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9698350.1"
                     /translation="MSNNKKKKRKKNNNYKNAKSTKSNKNTKKQMEKNQRTDYNIPTI
                     SFKSGLILIVSSLVSTVVFPLLLSIFGIDNRFGVVIGNSLITSFAVAYTRYFVETKRG
                     FSLGFFRLYILFALSFAIIGYFWIYKGIHI"
     gene            complement(9646..10797)
                     /gene="anmK"
                     /locus_tag="ACGI5H_002653"
     CDS             complement(9646..10797)
                     /gene="anmK"
                     /locus_tag="ACGI5H_002653"
                     /EC_number="2.7.1.170"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861795.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016773 - phosphotransferase activity,
                     alcohol group as acceptor [Evidence IEA];
                     GO_process: GO:0006040 - amino sugar metabolic process
                     [Evidence IEA];
                     GO_process: GO:0009254 - peptidoglycan turnover [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="anhydro-N-acetylmuramic acid kinase AnmK"
                     /protein_id="HFG9698351.1"
                     /translation="MYSVGLMSGTSLDGVDAVLAEISGNGRNTKVKQIEFITLEIPKD
                     IKDEIRKCCIEEESSVDLICSLNFKLGYLFSKAVKSVCHKANFHIANLDFIASHGQTI
                     FHIPRSYNNFVSSTLQIGEPAVIAYETNTKVISNFRVMDIAAGGEGAPLVPYSEFLLY
                     SDNNKNLALQNIGGIGNITIIPKSCNIDDVFAFDTGPGNMIIDGVCQRLFNRKYDKNG
                     YFASKGKINEEMLKDLMSHKYLSQAPPKSTGREVFGQVYLDNMLNKYKHVDKYDLIAT
                     VTMFTAKAIYYNYKNFILPKVNVDTLLIGGGGAHNLTLIGYIKELLLEVEVLTQDEYG
                     YSSDAKEALAFVILGNETLNNSFSNVISATGAKNKVILGNITPKPFGGK"
     gene            complement(11237..12256)
                     /locus_tag="ACGI5H_002654"
     CDS             complement(11237..12256)
                     /locus_tag="ACGI5H_002654"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003431379.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HFG9698352.1"
                     /translation="MLVKYLKGRSKYIALPLVVVSIINIYLFAIDIFKNKYSELIYLD
                     FLVLFIIMVFFVIDYINFRNSYTNLYNCIENSGEIDSYLVDGQSFEENLIKDIIENLK
                     IKNNSDIETYKQSLKELDEYIAKWVHEIKIPISSLSIITDRLSSIEDSLDIKNQVAKI
                     NFLVNSILYSSRSNTMFEDVFINKFNLEKLIKMSIKNNSFLLIKNNVEVSLNELENDV
                     YTDSKCMSYVLDQIINNAIKYSKEVGKIEFNSKKLENGVVLSIKDFGIGINEEDISRV
                     FDKGFTGKNGRNQLYKSTGMGMYFVKKMIDSLGHEIEVCSENGSYTIFNIYFYDISDY
                     LSLDS"
     gene            complement(12250..12930)
                     /locus_tag="ACGI5H_002655"
     CDS             complement(12250..12930)
                     /locus_tag="ACGI5H_002655"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898117.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HFG9698353.1"
                     /translation="MYRILLVEDDIDLSKEIALALEKWGFKVELIDDFEVVLDEFIDK
                     KPDVVLLDVNLPLYNGFYWCEKIRAISNVPLIFLSSRDSDMDLIMGINNGADDYITKP
                     FSIEILVTKINGIIRRVYNYSDSNSILYCEDLMFDVGKGIIKHKYKDKSIELTKNEIK
                     ILTLLLKNKNRVVSRESLMMTLWDNDEFVTDNALTVNMNRLRSKVKELGFDDFIKTKK
                     GVGYIIQC"
     gene            complement(13082..14989)
                     /locus_tag="ACGI5H_002656"
     CDS             complement(13082..14989)
                     /locus_tag="ACGI5H_002656"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891367.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="FtsX-like permease family protein"
                     /protein_id="HFG9698354.1"
                     /translation="MSILGIAYNNFKSNIRTYLAFFISMVFSVVVLTNFELLRYGDAI
                     NVLQDENKKFTLSVLVAVIMILSVFLFFFIWYATNIFFKNRSKEIGILSFMGLDLYTI
                     GKIYFVENMLIGISSCITGIIIGIITSRFFQVVIIKLSGFNIKVSNGLSIEAILYATL
                     IFISIFIIMAVKGFITICRSSVINLINISKKQEKIPKVGIGIYILAIVSIIVIGYGYY
                     LSTNIRTGDITSVLPVIGIIIVGTYGLFKSVMPVIFDIIIKNKKILFNGNNIIAINNI
                     NYRLNKNYKTYAIIAIIITTTISTLGASVAMKRIHKNAQEQRNVYTISIVSMDKDEVN
                     KKQIENIIKDTNKIKYSVNPELTILKKTDIKEAYDTTDTIMKYSDFCNTLKVNGNDKE
                     LKEYGERLVSGNNVIELKSPQTIASIATKEAKIKLDGQLYNISRGEVKVPVLGTGLNQ
                     SIIVVNDDTYFKLRDKGQQVYFYGAKVFQEENSQVMFNNIEKNLSLKNGYIQNGYKAQ
                     GESQWMKFAYVVLVFLFLVFAIVAGSIIYMKIYSDAYEDKEKYKILLKIGTTEKDINR
                     AILKEVAMFYTLPMLSATISSYFALRLAGDLLMTDLFGIYILSLVICLIIFIIYGAVS
                     VNKFKSVVYKN"
     gene            complement(14990..15742)
                     /locus_tag="ACGI5H_002657"
     CDS             complement(14990..15742)
                     /locus_tag="ACGI5H_002657"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439918.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HFG9698355.1"
                     /translation="MKEILKIKNISKDYGIKGFKTNVLKNISLTVNEGDFISIMGPSG
                     AGKTTLLNLMSTLDKQTSGEIILDGINISKVKNNELSKLRREKIGFIFQDYNLLDNMK
                     LMDNIALPLALGKKKSKEIEAKVFSIAKKFGLENHLDKYPYQLSGGQKQRGAAARSLI
                     TNPTVIFADEPTGALDSKSAYELLESLEKINRENNATIIMITHDPLTASYSNEVYMIN
                     DGNIKCKLNKGNSRKEFYGKIMDMLASMGGEM"
     gene            complement(16058..17212)
                     /locus_tag="ACGI5H_002658"
     CDS             complement(16058..17212)
                     /locus_tag="ACGI5H_002658"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427194.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HFG9698356.1"
                     /translation="MINKAIKFKFIIFYFFSYIIFAFASTKFTPFLSKLGYSAFERGI
                     ILSSYAITNILFQLLFGVLADKYQTMKKIVLISLSVYGIASVIMFSTESATFIIYLLL
                     VALSGGLLNTCCSLYDTWIIGCGDNINNYLSFIKTFGSIGWAIGSMVASYLILRFSYF
                     GLSVAIGLIVVLLIINILLLPDIEKINKKINVTNKDIIELLKDKKYILLVCILFLLYS
                     MVVANNCTVIDKMIALNATNSQISLKWSLQSLLEIPTYLAGSYLLKKYSSLNLLKLSA
                     IMITVQFLLFALTNDSNIIIILCVFQVFSTPLILITSKRLIFEVSPKKLRSSSQLIAL
                     SIFMGGSSLIIPTVAGFLSINIGYNYTLMVLSLFGCLAYCLIVLLNYLQE"
     gene            complement(17215..17682)
                     /locus_tag="ACGI5H_002659"
     CDS             complement(17215..17682)
                     /locus_tag="ACGI5H_002659"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891369.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucose transporter subunit IIA"
                     /protein_id="HFG9698357.1"
                     /translation="MFFKRKKEAITINSYIDGKIINLGEIPDKVFSTKVMGDGFAMIA
                     KDNILKSPTKGVISFIAQTNHAIGIKLQNDVQILIHIGLDSATTKKENFKLEVKQGQE
                     VNMGEKLVEIDNKLLENTLYIPLVIVENPNTVKYHLSNLNQEGNSGIKVINFD"
     gene            complement(17696..18184)
                     /locus_tag="ACGI5H_002660"
     CDS             complement(17696..18184)
                     /locus_tag="ACGI5H_002660"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003431368.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9698358.1"
                     /translation="MITNKIKNITAVLKDENIFLSVVMVCFLILPVLYIVYLELTSLF
                     TNISFSQLLNNDVNASLNLISNFSAVYSAYVIYNIKKNKEIKENMIAFYLVLLGQIFQ
                     IYTITIVIMFTYIYKFVGIKQIISSIKELQWGKSYKALFSSIAVCLISLFVMIIRIKL
                     IM"
     gene            complement(18198..19529)
                     /locus_tag="ACGI5H_002661"
     CDS             complement(18198..19529)
                     /locus_tag="ACGI5H_002661"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891372.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phospho-alpha-glucosidase"
                     /protein_id="HFG9698359.1"
                     /translation="MERKRQRILIAGGGSTYTAGIVTMLIESVAKFPIESIKLYDNND
                     ERQRKVAEACAIIVREKNPEIKFSYTTNPEEAFTDIDFVMAQIRVGLYALREQDEKIP
                     LKYGVVGQETCGAGGIAYGLRTIGPIIEMIDYMEKYSPNAWMLNYSNPAAIVAEACRV
                     LRPNSRIINICDMPVCLEEIFARVLGLNSRKDFDVRYYGLNHFGWWTSIKDKEGNDLM
                     PKLQEYCAKKGYEEFTPQGQHKESSWLETMRAAKDLLEIEPTTLPNTYLKYYLMADET
                     VEHANPNYTRANEIMDRREKDTFEECERIIKNGTARDTWFDASEHSQFIVELACALAF
                     NTQERFLLIVPNNGAIENFADDAMVEIPCLVGKDMVEPMSIGKIPTFQKGLMEQQVAS
                     EKLAVEAWIEKSYQKLWQSFTMSKTVPSAKVAKEILDEMIVANKDFWPTFK"
     gene            complement(19543..21108)
                     /locus_tag="ACGI5H_002662"
     CDS             complement(19543..21108)
                     /locus_tag="ACGI5H_002662"
                     /EC_number="2.7.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009906212.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0015144 - carbohydrate transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-glucoside-specific PTS transporter subunit
                     IIBC"
                     /protein_id="HFG9698360.1"
                     /translation="MMKKIQRFGGAMFTPTLLFAFAGIMVGFSIVFQNQSIMGSLATP
                     ENIWYQFWGVISSGAWMVFNQLPLLFAISLPIALAKKQQARACMEALATYLTFNYFVG
                     SMLSFWGKSFGVDFAAEISAGSGLVSIAGIKTLDTGMVGALLISGIVIYIHNRFYDKE
                     LPDFIGLFRGSSLVVAICFFVMIPVALLTCFIWPHIQNVIRHLQTFFINSGNIGVWCY
                     AFLQKILIPTGLHHFVYAPICYDSVVVPGGTSVYWATHIQDFQTSAKTLKEMYPIGFS
                     LSGLSKVFGSLGVFGAFYVTAKPEKKKKVLGLMIPATLTAVLTGITEPLEFTFLFVAP
                     LLFLVHAFLDACLQTISFALGVVGDFGGGIINWVVLNWLPLGMYHWKVYVVQVVVGII
                     FSFIWFFVFTFLIKKFDMKTPGREEDSEETKLYTKNEYLETKDEKGNKLSKASQQASE
                     YIKLVGGAENVVDVTNCATRLRLTLKDDSIISKEEDFKAVGAHGLVHNGKAIQIIIGL
                     SVPSVREEFENLL"
     gene            complement(21278..22063)
                     /locus_tag="ACGI5H_002663"
     CDS             complement(21278..22063)
                     /locus_tag="ACGI5H_002663"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422510.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MurR/RpiR family transcriptional regulator"
                     /protein_id="HFG9698361.1"
                     /translation="MRLEEMIFLNYNKLNDTDLLIWKYITANKKHCSKMSINELAMKC
                     NVSRATITRFVKKLDLKGFSEFKVLLSWESEKVHVIENQSFDIACNSIIKYVEDQKNK
                     DYDALCKLLYESRTIYAYGSGDIQNVVAKQIKRMFLSCQEIIYDFEGRTFDDSFYNIV
                     SKNDVMIIISLSGENENTLNIARRLKLIGTKIISITEFKNNTLTDLSDESIYISATNI
                     SFLQMHPSYKLTMLYFILIELLFIKYSIYKRHRMITEGIDCKL"
     gene            complement(22230..23429)
                     /locus_tag="ACGI5H_002664"
     CDS             complement(22230..23429)
                     /locus_tag="ACGI5H_002664"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898126.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008236 - serine-type peptidase activity
                     [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="S41 family peptidase"
                     /protein_id="HFG9698362.1"
                     /translation="MKKKVLFLVIILAFIILLGNSTYSQKNQLSEEEKVDDFNYVYNV
                     VKTGYPYLGVNKRLNNIDWLANKDEYTKRIKNTENDEEFIEELSSILSDLNNKHTEVI
                     DNKKRYELFKKSYSNNDWYDFLNDKKVVDRYDSMNLKIKMPDDIFVKKELILKDVIKG
                     QIGYMYLPSMSSKNGSINNDLKIIGDYINTLEKHKALIIDIRGNLGGSDRYWQGIVSK
                     LIKNDVKINGYRIYRNNNEIVKKYTNARNIKLNPVENLPASVKENAPKEIIKDFNDFE
                     DTSYTIKSTDDSKFKGNIYLLVDRKIYSSSESFAMFCKENKFATLVGETTGGDGGCID
                     PVLFNLKNSGLIVRMASCMYLNKNGICDEEFKTIPEFKVKDCKRTADFKDDNCIRKAL
                     ELENINY"
BASE COUNT         7925 a         4087 c         2462 g         9302 t
ORIGIN      
        1 ttcatttgct atttaaaatc aattttaagt tttcttctta taataaactt cctctttgtg
       61 gtctcatgtt agtctctaaa tttaaaattt tacaaaaaat tttcataaaa taaaattata
      121 ttgattgtat ctaaacaaat agggcaataa aataattaag tatagttact tacctttcaa
      181 gcaatattag ttttatgtta gaattttatt atattgattt acaggaggtt tgcatttgaa
      241 taatattaat tcacttaaag taataaaatt atctcttgga tgttctcttg ctatatttat
      301 tgcttggcta ttaaaattag aatattcaat ggttgctgga gttatagtac tacttacagt
      361 aaaggacact aaaagagaaa ctcttaaagg ctccattgga aagatttatg gttttctttt
      421 atgtactatt ttttcatatt tatgttttaa tattttagga tataatttga cttcattttc
      481 aatatttata tttataatta taccactttg ttttttgtta aatattcaag atgttattgc
      541 tatgtgtgta gtcatagcat cccattacta ccttcaagga gaaacttcta tcaaatggat
      601 tttaaatgaa gctggaatat ttgcagtagg aactggaata ggtgtcttaa taaatatgta
      661 tattccaaca aatatacata aaatccatga agttcaaaaa aagttacagg aagaagtgag
      721 tattgtactt atagacattg cagatattat tgtaaatcct aaaaaagaaa atggatatag
      781 tagagattta tatacattaa attcacttat tgacagcagt atttctgaaa cttacgataa
      841 tattaataat actttattaa gtgatactag attcttctta gagcatatgg atattataaa
      901 aagtcaacgg gatatcttag aaaatttgta tagttatgta tctcaactaa attctacacc
      961 accacaagct catattctat ctgcttttat acataagata ggttatactg aatttgaagc
     1021 tgaaacaggc aatcttcttc ttgaagaatt aaagagacta atgcttagta tgaaaaacca
     1081 gcctctacct gttgacagaa cagagtttga aaatagagct attttattcc tatgcttgac
     1141 tgagttaaaa cagtttttag ttaatcgtaa acatgctcag atgcttagag ataataattt
     1201 ttataaataa aaaggggaga aatctagcag ttgacctgac tacaaaatat cagatataat
     1261 attaaatgcg cccctagtaa gagggcgcaa tgtttataac ttattctact gtcatgatta
     1321 aatcattatt catatcgaac atacattatt tgaccaagtc caatattagc tttttcatca
     1381 gtgatttcta ttttaatagt cacatcattt tttttacagt acttcgctaa ttctgcacca
     1441 gaacgatttt taccactaaa atctaaagaa aatggcttat catatttaaa aggatattca
     1501 acaggtttac cctctggtgc taatgcaaac atcccatatg gtgtgttcat aaatcctatt
     1561 acagcaatcg taagatttga tgggtctaaa tttgattcac tacctgtaaa tgtaattgta
     1621 tttactgatg aattaactac actacatcga acaccttcat acattacatg tttttcattt
     1681 atatcttctc cttttttccc aaaatttcca acagcctttg ccccttcttg atgtggtaac
     1741 atagtgtgct tcccaggtgg tgctggtttc tgtgtctgtt ctggttttac cgtctgtact
     1801 attgcaccaa cttttggata tgctgtctta tcaaatggta atgggtggct aagactcttg
     1861 tatatgatat cctttcctgc tgatttatta gcatcaatat ctacatgata caaacgccca
     1921 tcaccaaaac ggataagatt ccactggtgg tcatttgatg tgctgtgtac ataataagat
     1981 tcaattccca tagcatcaca caaagctttc atgctcctag ccattcctga gcatgcacct
     2041 tttttagtaa ccaatgtata ggcagtattt gctccctcta ctgcattcca gtcaacatat
     2101 gttgtgttat ttttaatgtg attgtaggca actaaaatct tagcatctgt ggtcatattc
     2161 tttgtgattt tcttgttcat aaaatctgct gttgcttgtg ctactgagtt tagttgggct
     2221 tgtgacagct ttggaccata tacgctattg gttccagtga catagctttt tggtgttttt
     2281 gctgttacct ctttggctgt cataccataa actgtcatac tcatacctga gattaaaact
     2341 attgttgtaa tcaataactt ggtagctaac ttcctaattt tcttcatact taatattctc
     2401 ctttataaaa cattgttact tcctattctc taccattaat aaaattaatt taggatttaa
     2461 aaaggtggat tgtcaacatg tatatttctc cattcataca ttcgtgaaat atttaaattt
     2521 catggaaaat ctaatagata ttttctagat aatttgtata caatacaact cgcaaatcag
     2581 ggtgtttgct gttagtttga gaaaatgatg atgattaata cattcggaat ctttgaccta
     2641 taataaatac cattgtcttc aatcattaat aatggtaaga gtaaagagaa ttatcaataa
     2701 tacagttaaa atcaactttg tatacatttc atacattctc tcccaacaac attatacttc
     2761 ttataatttg tatattcaat acgttttctg ggaaaatata ggatatatct ataaaaatat
     2821 aaaaaaggag ttgaacttaa aatttgatta aaaaaaatca attttaagac aactcatttg
     2881 tattataaaa atgctatata ttattattaa gtaagtcaat attttagata tttatctatt
     2941 tcttattgac ttacgcttat agtctaactt atttgtttag ttgatatata acctagtttt
     3001 aagcattatt aatatttaaa taatcaagta tcctttttgt ttcttgtagt ttctgttctg
     3061 cctcatttaa gttttcttga attatagaaa tatatattat atctatcaac gtaagcattg
     3121 ctattcttga agaaatagct ccttctctaa gccttttttc tatatttggt actactagtt
     3181 ttaaatcact aatcttacta agatgattgt cactatattt agttatacaa atgaccttac
     3241 atccttttaa ttttgcattt tctatagact ttattacttc ttttgattct ccagagtaag
     3301 atattgctat agctatatct tctttatcta catttgaaga taccataagt tgtgtatgac
     3361 tatctaaaga ggtaaatgcc tgtttattta tccttaaaag tttcatctgt aaatctagtg
     3421 caactaaagc cgaaccacct actccaaata tatatacatt tttagccttt attatctgtt
     3481 caactgcttc ttttattata tctttttcat tcaacaacct tgtttggttg atagtctcta
     3541 tgtttttgtt tgtaattttg tttataacac tatctatatt acaatcatag ttttcatcta
     3601 catatgtgta ttcattttct ttgcccatca aatctttagc tatctcaatt tttaaatccc
     3661 caaaacccga atatcccatt tttctagaaa acctaactat acttgctgta cttgtttttg
     3721 agtttgacgc caattctgat acagaaagct tacttatagc ctctgtatta ttaagtatgt
     3781 aatcagctat ttttttatct acttccgtta aatcttcata tatctgtttt aattttaaaa
     3841 tgcaactcat actctatcac ctctacctat ttactataat atttcttctt agcaagtaaa
     3901 catgctccta aatctggagt caacactggt ctcactatac caaatctcgt tttattcaaa
     3961 tattttttaa gtggctctaa tattaaatct cctgacttaa acactccacc tgaataagat
     4021 acctttatct ttgtaccttg ttcaaaatga tgctctaatc ctattataag cctacttaat
     4081 tcataagctg catcatcaaa tattttacta gcagtattat caccttcaat aactgctttt
     4141 aaacatatcg tagcaaactt tgctatttct attctatctc cttttatttc atcatttaca
     4201 tattttatta tgtcataatc attctctata ttaagatgtc tttttattaa atcatataat
     4261 tttgtttttg aacaccttcc atcagactgc attgtgaaca tttttaaggt agccattcct
     4321 atataatacg ctgaaccttc atctcctaat acatagcccc atcctccaca tctgtgaaga
     4381 ttcccatctt tatctaaagc ctgtgctatt gaaccagtac ctgcaattat atttatacct
     4441 ttttccccat ttaaagaacc tgctaatgct atttctacat cattacctag agtataattt
     4501 atatgactat atgcattttt tgttgctact tctaatgcat acaatacttc ttttattttt
     4561 ccatatccag caagtccaac aaatgcatac gttatttctt ctacatttat cttagcatct
     4621 ttacaaactt cttccaaccc agttattaat aatttcgtta gattatcaaa tcctatttga
     4681 ttataatgac aagttccttt ggttatggtt cctactatat ttaattcttc atctactaat
     4741 gtaaatgttg ttttcgttcc tccaccatct acacctaaaa aatacatact atcctcctac
     4801 aatatcttta ataattcttt caatacttaa tatctaaaaa taaccttcca atgctgtttt
     4861 tttaatattg aaaggttatc agtactatta tttattttac aatttttcta ttgattttaa
     4921 agcttcactt atataacctt cttgtctatc taggatactc tttgcactat ccttatctaa
     4981 accacttttt atcataaata tagccaattt aacgctatta tctgcttctt ctaagaattt
     5041 ttctgcaaca tcatatttta catttgtagc tatcattatt attctttttg ctctttcaac
     5101 caacttttca tttgatgtct taacatctac catcaagttt gagtatactt ttcccatctt
     5161 aaccatagaa gctgttgtta acatattaca taccattttt tgagctgtac cacttttcat
     5221 tctagttgaa cccattatta cttctgcccc tactataatg tttattggta aatccgcttt
     5281 tttactcatt tcactattcg gattcatagt tattgatagt actgcacacc ccaattcctt
     5341 agcatactcc attgcaccta taacataagg agtccttcct gatgcagcta taccacatat
     5401 aacatcctta gatgtaactc ctctatctat tatatcttgc tttccaagtt ctttatcatc
     5461 ttcagcacct tctattgctt taaatattgc ttgatttcca ccagctatta tagcttgaac
     5521 aagctcaaaa tccactccgt aagttggagg acattctgtg gcatctagta ttcctatcct
     5581 cccactggta cctgctccta tatagaataa tctacctccc tgtttcattc tatctactat
     5641 tatattaaca gcttttgcta tactctcctt ttgttcttca acagcatagg ctacagtttt
     5701 atcttcgtta tttattaatt ctattatgcc taatgtatct tctttatcta tttgcaatgt
     5761 attcttattt ctaccttctg taactaaatt ttctaaagtt tttattaaca tatcatttcc
     5821 tcattttctt aatattaaat ttttaaacac attttaattc caactttcat aattatattt
     5881 ttataataaa ttaatatttt cataataaat tattttgttg agggtttaaa attaaacttt
     5941 tgccatggtt taatataatc taatataaat aattcttctt ttcttatata tcctactaca
     6001 ttcgatttac cactgttttt catatcagtc aaggctattt gtaactcccc tgcataatga
     6061 ccatattcac tactttcaat tactatatct cctcttttta ttattttagg agtattaaat
     6121 agttcaaatt tatatccttt atatttaaca cgagattgag tagaccttat cagactatca
     6181 gatatgtccc ctctattaaa atgtatttct tcaaagagta tcttcttctc aacttctcgt
     6241 atattttcct ctattgctac atcaaatgta accatatctt ttctcataga acctaatacc
     6301 tttagctcct catatgttgg ataacaattt gatattatta tatcatttat attattcata
     6361 gctattatat gctttacttg aatatctata ggtagatttc tgtgcatctc aattgttgga
     6421 agcccatcag ttacaggcca tggtccaaat gtagtttcat tttgacttgt tacaaaaact
     6481 gctgttctta atccatactt attaaatctt tctgtacatt ttataaagtg ttctaaattt
     6541 aatccactat atctatgtgg ataaaagtta tgacatccta tcaaattttc tttatttggt
     6601 tggtagtcca ttattgtatc tatataatta gtattattac tcatattgat ttctatttta
     6661 agattttgag gattaaaagt cattaatgcc tcttcagaac ctgtaaatcc catatcaagc
     6721 cttattccgt ctgccttcgt ctttttaaaa aaattcaaat ctttgtagct tatttctaat
     6781 tcaccaaata ctctgggatt tacatcaagt attacctcaa aacctttaaa cttagcgtat
     6841 tcatttatac ttttaaattt tttaattata ttttctttag tatctttaac tgataataaa
     6901 catgaaaata tacgtgtaaa tccattttca gcagctttat ctatataatc atatatttcc
     6961 ttagatgttg ttttttctgg ataaattgat attcctaatc ttcccatctg tgtcatctcc
     7021 ttatatccta tatgtgttta aatttatttc gaattacacg aaactttttt aaaaatttga
     7081 tgaaaaaaag tttcatatat atttataaaa aaagaaaagt ttaccttttc tttttttata
     7141 aacaatcaac aaaatatctt cgttacttat ttcataactg ttatactttg aaatttatac
     7201 taatctaata tagtttttaa tttccaatat agtttctaat taataagctt cttgctcttc
     7261 aactttttct tcatgaagca acctcttatc gtacatcttg acaaatggat agtaaattat
     7321 tattgatata gctatacata ataagttaag aactgaagct ctccaatctc caccagtggc
     7381 taaatatgcc cctactggtc ctggtaatgt ccaaggagca gtaactacta ctctggatac
     7441 taaattagca ctcatagcaa accatgaaac tgttgccatt actattggtg ctacaacaaa
     7501 tggtattatt aatattgggt ttaatactat tggcgctcca aatattattg gttcatttat
     7561 attgaatatt gctggtatta cagttgcttt tcctaaagac tttccataag ctgattttgc
     7621 tctaaatgca agaagtaaag ctaagcctat tgtagctcca gaacctccaa tccatataaa
     7681 ccattgaaaa aagggttcag cagcaatacc tggaactgct tgacccgcag catatgaagc
     7741 tgtattagca tctaataatt gtatccataa aggtcttgcc aatgaaccta ttattgatac
     7801 accatgtatt ccaaatgacc aaaaaaacgt tattaaaaat attagtataa ttactgatgg
     7861 taatgtgtca gtggctgaaa ctaatggagt tactaattta gctatgaagc catgccaatc
     7921 aaaccctagg aaataagtaa caatagccat taaaattatt attaatgcgg ctggtgtcag
     7981 agcttcaaaa gaccttgtga ctgatgctgg aactgcttct ggcatggtta tcttgaattt
     8041 agatttgtca gtaaatctat aaatctcaac acctattata gatgttacaa tagcaacaaa
     8101 cattgaacct ccaccaagat tagccattgg catttgccat ccttgaggaa ttgaattata
     8161 ccaagctaaa agttctggac tcttttcaac tatctttaat aaatcagggg taagaccctc
     8221 tattgcagta ggaactattg tcaaaaggaa tgtagctgta gctaataaac ctcctgtcaa
     8281 tccatctaac ttatatgact ttgccaaact ataacctatg ccaaatgtag aatatactga
     8341 tataataaaa aatgtcattc tatatggtag taatattgta actgcatttt cctttagata
     8401 ctgagttacc ccccatgaat ctggtaatgg aggaaatgct aatatcaaga aaaatgaccc
     8461 aactattata agtggtaatg aagctacgat tccatctctt acagctctta agtgacgttg
     8521 ttctgccaat ctggccatag aagttgataa tttagtgtct aaaaattctg taaatttatc
     8581 tagcatcttt tctctcctta attaatattt atttttatta tcattaaaat ttttataaaa
     8641 ttaactttct tctaatctaa caacactgca actactattt actcaacagc tcttgaactt
     8701 gttttaataa ctttggtcct cctaatggac tataagcttg tgcttgtatt aatgcacatg
     8761 gtacactaac ctcatcagca aaagctttta aatagtcaaa tctatgtcta acttgtggag
     8821 ctaccatagc aatatcccat ccatttttaa cttcatcctc aaactcttga gtaccaacag
     8881 ccaaaacatc tatatctatt ccattttttg ctccttcttt ttgtaatgca ttaactgcta
     8941 tagcacttga catccctgat gaacaaacaa ataatactct catattgatt ccccctgttt
     9001 ttttatttct tttcaatcat tatagcatgt atttttgatt acaggaatac gtttgtatat
     9061 atttttttca tattttacat tttaaattgt aattttattt catacattta tatcttgctt
     9121 taattgcttt atttatctaa tcattctttt gtctaaaatt acacactact taaaatactc
     9181 atatcttttc ttaaaaaaga aaaaagacta tcttattatt aacataaaat agtctcaata
     9241 cttttttaaa tatgtattcc tttatatatc cagaagtaac ctattattgc aaatgataaa
     9301 gcaaataaaa tatacagtct aaaaaatccc aaagaaaaac ctctcttagt ttcaacaaag
     9361 tatcttgtat atgcaactgc aaaagatgta attaatgaat ttcctataac aactccaaat
     9421 ctattatcta ttccaaatat agataataac aaaggaaaaa ctacagtact tactagagat
     9481 gaaactatta atattaatcc acttttaaaa cttatagttg gaatattata atctgttctt
     9541 tgatttttct ccatttgttt cttagtattt ttattacttt ttgtactttt tgcattttta
     9601 taattattat ttttctttct tttctttttt ttattattag acatgtcatt tacctccaaa
     9661 aggtttaggt gttatattcc ctaaaataac tttattttta gcccctgttg cagatattac
     9721 attagaaaaa gaattattta atgtttcatt gcccaagatt acaaatgcca aagcctcctt
     9781 tgcatcagaa gaatacccat attcatcttg agttaatact tcaacctcta ataataactc
     9841 ttttatatat cctattaaag ttagattatg agctcctcca cctccaatta ataaagtatc
     9901 tacattaacc tttggaagta tgaagttttt ataattataa tatatagctt ttgccgtaaa
     9961 catagttact gttgctatca aatcatattt atctacatgt ttatatttgt taagcatgtt
    10021 atccaaataa acttgtccaa atacctctct tccagtgctt ttaggtggcg cttgactaag
    10081 atacttatga ctcatcaaat cttttaacat ttcttcatta attttacctt ttgatgcaaa
    10141 gtatccattt ttatcatact ttctattaaa taatctttga catactccat ctattatcat
    10201 atttcctggt cctgtatcaa atgcaaatac atcatctatg ttacatgatt taggtattat
    10261 agtaatattt cctattccac caatattttg aagtgctaaa tttttattgt tatcactata
    10321 taataaaaat tcactatatg gtactaatgg agcaccttct ccacctgctg ctatatccat
    10381 tactctaaaa ttagatatta cctttgtatt tgtttcatat gctataactg ctggttcacc
    10441 tatttgaagc gttgaagata caaaattatt ataacttctt ggtatatgaa agattgtttg
    10501 accatgagat gcgataaaat ccaaatttgc tatatgaaag tttgctttat gacacactga
    10561 ttttacagct ttactaaata aatatccaag cttaaaattt aagctacaga ttaaatcaac
    10621 actcgattcc tcttctatac agcactttct tatttcgtct tttatatctt taggaatttc
    10681 tagagttata aattctattt gcttaacttt agtatttcta ccattcccac taatttcagc
    10741 tagtactgca tcaactccat ctaaggaagt tcctgacatt aaacctacac tatacatagt
    10801 tatcatcctt ttaagtttat agttattcct ccccaaatca aggtattaag tttaataatt
    10861 ttagaattaa tcttatttca tctttaatta cgataattta ctcttatgaa attaattgag
    10921 ttaatcttat acacgttttt taccttagct aaatcttaca ttaatttatt ttcagtgtca
    10981 atgtaatacc atgtaatttt ttttcacaaa caaaacatat tctctctcca aaaaccatat
    11041 taaaatagtt actacaaata aaaaacatac caggtaccta tctgatatgt ttttcatata
    11101 taataattat tattttataa tatagataga gcatcattta aggcactaat taaatcttca
    11161 ctattttcaa gaactaaatt tattcttatt gtatatgtcg atttgtatat gatgatagat
    11221 tttatagtct aataacctaa ctatctaggc ttaaataatc cgatatatca taaaaataga
    11281 tattaaaaat tgtatatgaa ccattttccg aacatacctc aatctcatgc cctaaactat
    11341 ctatcatttt ctttacaaaa tacatcccca ttccagtaga cttatacaat tgatttcttc
    11401 catttttccc cgtaaatccc ttgtcaaaaa ccctagatat atcttcctca tttataccta
    11461 taccaaaatc ttttatagat aataccactc cattttctaa cttttttgaa ttaaattcaa
    11521 tcttaccaac ttcctttgaa tactttatag cattattaat aatttggtct aaaacatatg
    11581 acatgcattt agaatctgtg taaacatcat tttctaattc attcaaacta acttctacat
    11641 tattttttat aagcaaaaat gaattatttt ttatagacat ttttatcaat ttttctaaat
    11701 taaatttatt tataaataca tcttcaaaca tagtgttgct tctactacta tacaaaatag
    11761 agtttactaa aaaatttatc tttgcaacct gattcttaat atccaaacta tcttctatgc
    11821 tacttaacct atctgtaatt atacttaaag aagatattgg aatttttatt tcatgaaccc
    11881 atttagctat gtactcatcc aattctttta atgattgttt ataagtctct atgtcactat
    11941 tattttttat ttttaagttt tctataatat cttttattag attttcttca aaagattgtc
    12001 catcaactaa ataactgtct atttcaccac tattttctat acaattatat aaatttgtgt
    12061 aactatttct aaaatttata taatctataa caaaaaatac cattattata aacagtacta
    12121 aaaaatctaa atatattaac tctgaatatt tatttttaaa aatatctata gcaaataagt
    12181 agatatttat tatactaact acaactaaag gtagagcaat atacttagac ctacctttca
    12241 aatattttac tagcattgta ttatatatcc tacccccttc ttagttttta taaaatcatc
    12301 aaaacctagt tctttaactt tacttctcaa tctattcata tttacagtaa gtgcattgtc
    12361 tgtcacaaac tcatcattat cccatagagt catcataaga ctttcccttg atacaaccct
    12421 attcttattt tttaataata atgttaaaat ttttatttcg tttttagtca actctatact
    12481 tttatcctta tacttatgtt ttataatccc tttccccaca tcaaacatca aatcttcaca
    12541 atacaaaata ctattagaat cactataatt atagactctt cttattatac catttatttt
    12601 ggtaaccaat atttctatag aaaatggttt ggtaatgtaa tcatctgctc cattatttat
    12661 acccattatt aaatccatat cagaatctct tgatgataaa aatattaatg gtacatttga
    12721 aatagctctt attttttcgc accagtaaaa tccattatat aatggtaaat ttacatctaa
    12781 aagtactaca tctggttttt tatctataaa ttcatctaat actacctcaa aatcatcaat
    12841 taattctact ttaaatcccc atttttcaag tgctaatgca atctcttttg ataaatcaat
    12901 atcgtcctct actaataaaa ttctatacat ttgtatattc tccattatcc taatatttca
    12961 ctatgctatg aattattaat atcataacat attttatatg aatttattac ccaaattatt
    13021 tagttaatca acaaggagac tcttattaca agaatctcct ttctctttat taatatatca
    13081 actaattttt atacactaca ctcttaaact tattaacaga tactgctcca tatattatga
    13141 atattatcaa acatatcact aaacttagta tatatatacc aaataaatcg gtcatcaata
    13201 aatctcctgc taatctcaat gcaaaataac tagatatagt tgcacttaac attggcaaag
    13261 tataaaacat agctacttct ttaagtatag ctctatttat atctttttct gtagtaccta
    13321 tttttaacaa aatcttatat ttctctttat cttcatatgc atcactatat attttcatat
    13381 atattatact tccagctaca attgcaaaga ctaagaataa aaacacaagc actacatatg
    13441 caaacttcat ccattgactc tcaccttgag ctttatatcc attttgaata tacccatttt
    13501 ttaaacttaa attcttttca atattgttga acattacttg actattttct tcttgaaata
    13561 cctttgcacc ataaaaatac acttgttgac ccttatctct tagtttaaaa tatgtatcat
    13621 catttaccac tataatactt tgattaagtc ctgtccctag tactggaact tttacttctc
    13681 cccttgaaat attatataac tgaccatcaa gttttatctt ggcttctttt gtagctattg
    13741 atgctatcgt ttgagggctt tttaactcta ttacattatt tccactaact aatctttcac
    13801 catactcttt taattcttta tcattgccat tcactttaag agtattacaa aaatcactat
    13861 atttcattat agtatctgtt gtatcataag cttcttttat atctgttttc tttaaaattg
    13921 ttagttctgg atttactgag tactttatct tattagtatc ttttattata ttctctattt
    13981 gttttttatt cacttcatct ttatccattg aaactatgct aatagtgtac acatttcttt
    14041 gttcttgggc attcttatgt atacgcttca tcgcaactga agcaccaaga gttgatattg
    14101 ttgtagttat aattatagct attatagcat aagttttata gtttttattt aatcggtagt
    14161 ttatattgtt tattgcaatt atattatttc cattaaataa tattttttta tttttgatta
    14221 taatatcaaa tataacaggc ataactgatt tgaataatcc ataagtacct actattatta
    14281 tacctataac aggtagtaca ctagttatat ctccagttct tatattggta gaaagatagt
    14341 agccatatcc tattactata attgatacta tagctaatat atatatacct attcctacct
    14401 ttggtatttt ttcttgtttt ttagatatat tgattagatt tattacacta cttctacata
    14461 ttgttataaa accttttaca gccattatta taaatataga aataaagatt aaagtagcat
    14521 atagtatagc ttctatacta agtccattag atacctttat attaaatcca gataacttta
    14581 ttatcactac ttgaaaaaat ctagatgtta ttatccctat aattattcct gttatacaag
    14641 aacttattcc tataagcata ttttctacaa aatatatttt tcctatagta tataaatcta
    14701 atcccataaa agacaatatt ccaatttctt tagacctatt cttaaaaaat atatttgttg
    14761 cataccatat aaagaaaaat aaaaatactg atagtatcat tattacagct actaacactg
    14821 atagtgtaaa ttttttattt tcatcttgta acacatttat agcatcacca tatcttaata
    14881 attcaaaatt agttagcaca actactgaaa aaaccataga tataaaaaat gctagataag
    14941 ttcttatgtt actcttaaaa ttattataag caattccaag tatactcact tacatctcac
    15001 ctcccataga ggctagcata tccataattt ttccataaaa ttcttttcta ctatttcctt
    15061 tgtttaattt acactttata tttccatcat ttatcatata tacttcattt gaataacttg
    15121 ctgttagagg gtcatgtgta atcattataa tagtagcgtt attttctctg tttatttttt
    15181 ctaatgattc taaaagttca tatgctgatt tagagtctaa agcaccagtt ggctcatcag
    15241 caaatatgac tgttggattt gtaattaatg acctagctgc tgcgcctctt tgtttttgtc
    15301 ctcctgataa ctgatatgga tatttatcta aatgattttc taatccaaat tttttagcta
    15361 tagaaaatac cttagcttct atctccttac ttttcttttt tcctaatgct agaggaagtg
    15421 ctatattgtc cattagtttc atattgtcta atagattata gtcttgaaat ataaacccta
    15481 ttttttctct tcttaatttt gatagttcat tattttttac ttttgatata ttaattccat
    15541 ctagtattat ttctcctgaa gtttgtttgt caagtgtaga cattaaattt agcaatgttg
    15601 tctttcctgc accagatgga cccattattg atataaaatc accttcattg actgtaagag
    15661 atatattttt taacacattt gttttaaatc cttttattcc ataatctttt gatatatttt
    15721 ttatttttaa tatttctttc ataataatag cctccagttg ctaatttttt aatatatatt
    15781 tattttaaag gttttatata aataaatcct taagtaaata ttacatttta actgttagca
    15841 ttacactttt gtaacatatg gaagactatt ataattatag tagaaatatc ttaaaataaa
    15901 agcatgattt acttctttgt ataaacaaag aaaagaagct cctaagaagc ctctaatcta
    15961 tacaattatt cttctctata aaaaaccaaa atacacattg attgtggcaa atacagatac
    16021 tataaacaag tgatattact actatatatt aaaacaatta ttcctgaaga taattcaata
    16081 agactatcaa gcaataagct aagcatccaa aaagacttaa taccattaat gtataattat
    16141 acccaatatt aatgctcaaa aaaccagcaa cagttggaat aatcagagat gaacctccca
    16201 taaatatact taaagctatt aattggctac tacttctaag ttttttagga gaaacttcaa
    16261 atattaatct ttttgaagta attaaaatta aaggagtaga aaacacttga aaaacacaca
    16321 gtataataat gatatttgaa tcatttgtta aagcaaataa tagaaactga actgttatca
    16381 taatagcact taattttaat aagtttaaac tgctatattt ttttaataaa taagaaccag
    16441 ccagatatgt tggtatctct aacaatgact gtaaagacca ctttaaagat atctgagaat
    16501 ttgtagcatt taaagctatc attttatcta ttacagtaca gttatttgct accaccattg
    16561 agtataataa gaataaaata catactagta agatatattt tttatctttt aataattcaa
    16621 taatatcttt attagttaca tttattttct tattaatctt ttcaatatca ggtaataata
    16681 gtatatttat aataagtaat actacaatta aaccaatcgc tacagataat ccaaaatatg
    16741 agaatctaag aatcaagtaa gatgctacca tacttccaat agcccatcca atcgacccaa
    16801 aagtcttaat aaatgacaaa taattattaa tattatctcc acaacctatt atccatgtat
    16861 catataaact acagcaagta tttaataatc ctcctgataa agcaacaagt aataagtata
    16921 ttataaaagt tgcagattca gtagaaaaca taataactga tgcaattcca taaactgata
    16981 aactaattaa aacaattttt ttcattgttt gatacttatc agctaatact ccaaataata
    17041 attgaaacaa tatattggtt attgcatagc tcgataatat aattcctctt tcaaacgctg
    17101 agtaacctaa ttttgataag aaaggtgtga attttgttga agcaaaggca aaaataatat
    17161 atgagaaaaa atagaatatg ataaatttaa atttaatcgc tttattaatc ataatcaatc
    17221 aaaattgata actttaatac cactatttcc ttcctgattt aagtttgaaa gatgatattt
    17281 taccgtatta ggattctcta caataactaa aggaatatat aaagtatttt caagtaactt
    17341 attatcaatt tctactaact tttcccccat attaacttct tgaccttgtt taacttctaa
    17401 tttaaagttt tctttttttg ttgttgcact atccaatcca atatgaataa gaatttgaac
    17461 atcattttgc aatttaattc ctatagcatg gttagtttga gcaataaaac ttattactcc
    17521 tttagtcggt gatttaagaa tattgtcctt tgctatcata gcaaatccat ctcccattac
    17581 cttagttgaa aatactttat caggaatttc tccaagatta attatttttc catcaatgta
    17641 tgaattaatt gtaattgctt ctttttttct tttaaagaac attatagaca ctcctctaca
    17701 taattaactt tattctaatt atcattacaa ataacgatat taagcatact gcaattgagg
    17761 aaaaaagagc cttatagctc tttccccatt gtagttcttt aatactgctt atgatttgtt
    17821 taattccaac aaatttataa atataggtaa acatgataac aatagttatt gtgtaaattt
    17881 ggaatatctg ccctaataag actaaataga aagcaatcat gttttctttt atctctttat
    17941 tcttttttat attgtaaata acatatgcac tgtatactgc actaaagtta gagattaaat
    18001 ttaaacttgc attaacatca ttgtttaaaa gttgtgaaaa tgaaatattt gtaaataatg
    18061 atgtcaattc taaatacact atatataaaa caggtaatat tagaaaacaa accataacca
    18121 ctgaaagaaa tatattttca tcttttaata ctgctgtgat attttttatt ttatttgtta
    18181 tcatgttttt gttctcctta tttaaaagtt ggccagaaat ccttattagc cacaatcatt
    18241 tcatctaaga tttcttttgc tacttttgca cttggaacag ttttactcat agtaaacgac
    18301 tgccataatt tttgataact tttttctatc catgcttcta cagctaattt ttcagaagca
    18361 acttgttgtt ccattaaacc tttttggaaa gttggaattt tacctataga cataggttca
    18421 accatatctt ttccaacaag gcaaggaatt tcaaccattg catcatctgc aaaattttca
    18481 atagctccat tattaggaac aatcagtaaa aatctttcct gagtattaaa tgctaatgca
    18541 caagctaatt caacaataaa ttgagaatgt tcacttgcat caaaccatgt atctcttgct
    18601 gtgccatttt ttataattct ttcacattct tcgaatgtat ccttttctct tctatccata
    18661 atttcatttg ctcttgtata atttggatta gcatgttcaa cagtttcatc agccattaaa
    18721 taatatttta aataagtatt aggtaatgta gtcggttcta tttccaataa atcctttgct
    18781 gctctcatag tttctaacca actagattct ttgtgttgac cttgaggtgt aaattcctca
    18841 tatccttttt tagcacaata ttcctgtaat ttaggcatta aatcatttcc ttctttgtcc
    18901 ttaatacttg tccaccaccc gaaatgattc aatccataat atctaacatc aaagtcttta
    18961 cgagaattta aacctaaaac tctagcaaat atttcctcta aacatactgg catatcacaa
    19021 atattaataa ttcttgaatt tggtcttaat acacgacatg cttctgcaac tatagctgct
    19081 ggatttgaat aattaagcat ccaagcattt ggagaatatt tttccatata atcaatcatt
    19141 tcgattattg gacctattgt tcttaatcca taggcaattc cacctgcccc acaagtttct
    19201 tgaccaacaa ccccatattt tagtggaatt ttttcatctt gttcacgtaa agcatataaa
    19261 ccaacacgaa tttgtgccat tacaaaatca atatcagtaa atgcttcttc tggatttgtt
    19321 gtataactaa atttaatttc tggatttttc tctctaacaa ttattgcaca tgcttcagca
    19381 acttttcttt gtctctcatc attattatca tataatttaa ttgattcaat aggaaattta
    19441 gcaacacttt caattaacat tgttacaatt ccagcagtat aagtactacc cccaccagca
    19501 attagtatcc tctgtctttt tctttccatc tttccttctc ctttataata aattttcaaa
    19561 ttcttctctt acacttggta ctgaaagccc aataataatc tgaatagctt ttccattatg
    19621 cactaaacca tgtgcaccta ctgccttaaa atcttcttct ttagaaataa ttgagtcatc
    19681 tttcaaggtt aatctcaacc tcgtagcaca gtttgtaaca tctacaacat tttctgctcc
    19741 accaactaat tttatgtatt cagatgcttg ttgagaggct ttactcaatt tatttccttt
    19801 ttcatcttta gtttctaagt attcattttt agtatatagt tttgtttctt cactatcttc
    19861 ctctctacca ggagttttca tatcaaactt cttaattaag aaagtaaata caaagaacca
    19921 gataaatgaa aatataatcc ctacaacaac ttgaacaaca tataccttcc agtgatacat
    19981 tccaagagga agccaattta atacaaccca gttaataatt cctccaccaa aatcaccaac
    20041 aactcctagg gcaaacgaaa tcgtttgcaa gcatgcatct aaaaatgcat gtactaggaa
    20101 taaaagtggt gctacaaata aaaatgtaaa ttctaacggc tcagtaattc cagttaatac
    20161 tgcagtaaga gtagcaggaa tcattaaacc taatactttt ttcttttttt ctggctttgc
    20221 agttacatag aaagcaccaa atacacctaa tgaaccaaac accttcgata atccggataa
    20281 tgaaaatccg attggataca tttcctttag agtcttagct gaagtttgaa aatcctgaat
    20341 atgagtagcc caatatactg atgtaccacc tggaacaaca acactatcat aacaaattgg
    20401 tgcatataca aaatgatgta atccagttgg tattaaaatc ttttgtaaga atgcataaca
    20461 ccaaactcct atatttccac tatttataaa aaacgtttgc aaatgtctaa taacattttg
    20521 aatatgaggc caaataaaac aagttaataa tgcaactggt atcataacaa agaaacaaat
    20581 tgcaactaca agtgatgagc ctctaaataa tccaataaaa tctggcagtt ctttatcata
    20641 aaatctatta tgaatataaa tgacaatacc tgatattaac aaagcaccaa ccataccagt
    20701 atctaatgtt ttaataccag caatgcttac aagtccactt ccagcactta tttcagctgc
    20761 gaaatcaact ccaaagcttt ttccccaaaa acttaacata gaacctacaa aataattaaa
    20821 agtcaaatac gttgctaaag cctccataca agctcttgct tgttgctttt ttgcaagtgc
    20881 tattggtaaa gaaatagcaa ataataatgg caattgatta aataccatcc aagctccact
    20941 agatattaca ccccaaaatt ggtaccaaat attttctggt gtagcaagtg aacccataat
    21001 tgactgattt tgaaatacaa ttgagaatcc aaccattatc ccagcaaaag caaataatag
    21061 tgttggtgta aacattgccc ctccaaaacg ctgtattttc ttcatcatat aaattactcc
    21121 cctcctcata tttttagttt atctttggcc ttagatatct attattttaa caggttaata
    21181 aatatataca atctttaggg tacattcgga gcttattcac agtcaaataa gtttttgcac
    21241 atttttatgt tcaaattctc ataaaaaaaa agaatgacta caatttgcaa tcaatccctt
    21301 ctgtaatcat tctatgcctt ttataaatac tatatttaat aaataataac tcaatcaata
    21361 taaaatataa cattgtcaat ttataactag ggtgcatttg taaaaatgag atattagtcg
    21421 ctgaaatata aattgattca tcacttaaat cagtcaatgt attattttta aactctgtaa
    21481 ttgaaattat tttagttcct attaatttta atcttctagc aatattaagt gtattctcat
    21541 tctcaccact tagggatata ataatcataa catcattttt actgacaata ttgtaaaaag
    21601 aatcatcaaa tgttcttccc tcaaaatcat atattatttc ttgacatgat aagaacattc
    21661 tctttatctg ttttgcaacc acattttgaa tatcacctga accataagcg tatattgttc
    21721 ttgattcata aagaagttta cacaatgcat cataatcttt atttttttga tcttcaacat
    21781 acttaattat tgaattacat gcaatatcaa atgactgatt ttctatgaca tgaacctttt
    21841 ctgattccca gcttaataat actttaaact cactgaaacc ttttaaatct aattttttaa
    21901 caaatcttgt aatagttgca cgagacacat tacatttcat agcaagttca tttattgaca
    21961 tcttactaca atgtttttta tttgcagtta tatatttcca tattaataaa tctgtatcat
    22021 tcaatttatt ataatttaaa aaaatcattt cttctaatct cataaactat tacccccttt
    22081 aattaaaaat cgtcataaat attataccaa tattcaacat taaattacag cgtattctta
    22141 tatttactat ttagcccata aaattgacta taaaaaatac tgctataatt gatgtttaaa
    22201 aaaatgtagt tttaatttta ttcttttatc taataattaa tattttcaag ttctagtgct
    22261 tttcttatac aattatcatc tttaaaatca gcagtccttt tacaatcttt tactttaaat
    22321 tctggaatag ttttaaattc ctcatcacat attccattct tatttaaata catacaactt
    22381 gccattctaa ctattagacc actatttttt aaattaaaca atacagggtc tatacaccct
    22441 ccatctccgc cagtagtttc accaactaaa gtcgcaaatt tattttcttt acaaaacatt
    22501 gcaaatgact ctgatgatga atatattttt ctatcaacaa gtaagtatat attaccctta
    22561 aattttgaat catctgtaga ttttatagta taggaagtat cttcaaaatc attaaaatct
    22621 tttataattt ctttaggtgc attttccttt acacttgctg gtaaattttc tacaggattt
    22681 aattttatat ttcttgcatt tgtatatttt tttactattt cattattatt tctataaatt
    22741 ctataaccat ttattttgac atcatttttt atgagtttag atacgattcc ctgccaatac
    22801 ctatcacttc cacctaaatt acctcttata tcaataatta aagctttatg tttttctaaa
    22861 gtgttaatat aatctccaat tatttttaaa tcattattta tagagccatt ctttgatgac
    22921 attgatggta aatacatata tccaatctga cccttaataa catcctttaa aattaattct
    22981 ttttttacaa aaatatcatc tggcattttt attttaagat tcatagagtc atatctatcc
    23041 acaacttttt tatcattaag aaaatcatac caatcattat tagagtatga tttcttaaaa
    23101 agttcatatc ttttcttatt atctattact tctgtgtgtt tattatttaa atcagataat
    23161 atagatgaca gttcttctat aaattcttca tcattttcag tgttttttat tcgttttgta
    23221 tattcatcct tatttgctaa ccaatcaata ttattaagcc tcttatttac acctagatat
    23281 ggatatcctg tctttacaac attatacaca taattaaagt catccacctt ttcctcttca
    23341 gacaactgat tcttttgaga ataagtagaa ttacctaata atattataaa tgctaaaata
    23401 attactaaaa ataatacttt ctttttcatg taattctcat ccactttcag attttatatt
    23461 ttaatacatt gtatcattat tttattatca cctaaacagt taaaagaaat tcttgaagat
    23521 atattccact attattctct ttaaaaattt ttatttgtat tttcaaaatt atttcatgaa
    23581 agttataaaa taacaattat attcaaatat ctattttact gctatatcct gaaagtaaat
    23641 tcttatcagt gatatactaa aaaagatatg ctaaaaaatt tatccattat aatgacttaa
    23701 atttagatac tttactgatt tttatttatt agttgagaaa gatattgata attaaaaata
    23761 ttgataacta tagaaa
//
LOCUS       DAYAOO010000063        23638 bp    DNA     linear   BCT 12-OCT-2024
DEFINITION  TPA_asm: Clostridioides difficile isolate ST8-SSI-h139-18
            SAMN40601845-rid21577343.denovo.063, whole genome shotgun sequence.
ACCESSION   DAYAOO010000063 DAYAOO010000000
VERSION     DAYAOO010000063.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN40601845
            Sequence Read Archive: SRR28438827
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 23638)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 23638)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-MAY-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-MAY-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002157583.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002157583.1
            Genome Coverage       :: 163x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/11/2024 16:19:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 4,038
            CDSs (total)                      :: 3,963
            Genes (coding)                    :: 3,930
            CDSs (with protein)               :: 3,930
            Genes (RNA)                       :: 75
            rRNAs                             :: 6, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 60
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 33
            CDSs (without protein)            :: 33
            Pseudo Genes (ambiguous residues) :: 0 of 33
            Pseudo Genes (frameshifted)       :: 7 of 33
            Pseudo Genes (incomplete)         :: 25 of 33
            Pseudo Genes (internal stop)      :: 11 of 33
            Pseudo Genes (multiple problems)  :: 8 of 33
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..23638
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN40601845-rid21577343.denovo.063"
                     /isolate="ST8-SSI-h139-18"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Denmark"
                     /collection_date="2018"
                     /collected_by="Statens Serum Institute"
     gene            complement(320..2557)
                     /locus_tag="ACGI5H_002665"
     CDS             complement(320..2557)
                     /locus_tag="ACGI5H_002665"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888352.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HFG9698363.1"
                     /translation="MKYNNTSEINPLDYILGQERAVEAMELGLKINNPAYNIYIAGEP
                     GTGKSTYALKVLNEYASKKNTHKDWCYIYNFENPREPIIVELEKGFGRELKKDMEKLI
                     ESLLEDFKNAFESENFEIEKNKLLDEYEIEKDMLLKQIKKYGEEKGFKLKQSKMGIVF
                     IPLKEEEDESDESDEEFYKAKRELENMAIQVVYKIRNLEEIAEKAVLELEEEIAKLVV
                     EPHIKRLCEKYENYDKIQTYLENIKKDIIEYMYLFYLDEEELKDKYDKEHFIKYKINL
                     FVDNGSSKNKESAPVVVEINPSPANLFGKAEYDYANGNIKTDFTKLLSGAFHRANGGY
                     LVLYADQLLKYTMSWEILKKTLQTKKVILETQTAIKPENMPLDVKLVLIGSHYIYDIL
                     YRYDEDFEKYFKVFVDFDSEMDKNEDNEEGIARFIAYQCDKNNLRHFTKSAVEEVIKF
                     STRLSGDLEKLSTKFNKIMEVVIEGSAYAEFRNSEYTEQCDVKKAISEKRKRINRVET
                     HMDESIENGFTLIETEGRKVGVINGLSVLSTGEYSFGRASRITATTSPGSKGIVNIER
                     EVNMSGSIHNKGVLILGGYLSENFAQDLLLSLNAYVCFEQNYGGIDGDSASSAELYVL
                     LSSLSGVSIKQNIAVTGSINQKGDIQVVGGISEKIEGFYSICKTKGLNGEQGVIIPRK
                     NQRNLVLSDEVNDAVRDGKFKIYTVERVEEAIEILTDVKFEEIKKLVKEKLISFSKIQ
                     TVSKE"
     gene            complement(2663..3577)
                     /gene="queG"
                     /locus_tag="ACGI5H_002666"
     CDS             complement(2663..3577)
                     /gene="queG"
                     /locus_tag="ACGI5H_002666"
                     /EC_number="1.17.99.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888351.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0051539 - 4 iron, 4 sulfur cluster binding
                     [Evidence IEA];
                     GO_function: GO:0052693 - epoxyqueuosine reductase
                     activity [Evidence IEA];
                     GO_process: GO:0008033 - tRNA processing [Evidence IEA];
                     GO_process: GO:0008616 - queuosine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA epoxyqueuosine(34) reductase QueG"
                     /protein_id="HFG9698364.1"
                     /translation="MDNKELKAFCNLIGLNCVGVAGVDKYDNLEKILKDRQQKGYLTG
                     MEEPIIENRINPRHIMKDANSIIVCAFPYHINRQEKNKNSNLSKYCHGKDYHIVVKDF
                     LQQICDYISKTVTDFKYKLFADNGPLVDRYLAYLSGIGYFGINNNIITDEYGSYVFIG
                     YIVNNYKFEEDKPLEKSCFKCGKCVKYCPGNAILGNYDMNPKKCLSYITQKKGDLSEK
                     EKVVLKNGKKVFGCDICQEVCPHNVEIPTTHILEFKENIIDYLNYDEIQNISNKEFKR
                     KYGDRAFSWRGRNIIKRNMEIILDKYDD"
     gene            4599..5003
                     /locus_tag="ACGI5H_002667"
     CDS             4599..5003
                     /locus_tag="ACGI5H_002667"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888350.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RusA family crossover junction
                     endodeoxyribonuclease"
                     /protein_id="HFG9698365.1"
                     /translation="MIKITIPGRPISKSNFKLHNINGQAWMPSKGKYSKYLAYENMIA
                     GFINQQYQGETVEENLITVLKLFFPNKRMGDLHNYPKSICDGIEKSGIIKNDKQLKPV
                     LLFDFIDKDNPRVEIELYPVSKYDISYNIFEK"
     gene            complement(5260..6255)
                     /locus_tag="ACGI5H_002668"
     CDS             complement(5260..6255)
                     /locus_tag="ACGI5H_002668"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888349.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldo/keto reductase"
                     /protein_id="HFG9698366.1"
                     /translation="MRNLGNTNMKIKRVGFGGIPIQRITQDDTNLVINELEKQGINFI
                     DSARGYTISEEAIGIAIEGKRDKFFLATKSMSRDYDSMKRDVEISLNNFKTDFIDLYQ
                     FHNVKEEEYDNLFKDKMAYSALLEAKEQGKIKHIGITSHNLNTIEKAIEDGKFDTIQF
                     PYNIVEGQADEVFKKAHEKGIGIIVMKPLAGGALDNATLAIKYILSKEYIDVVIPGME
                     SVEQVRQNVAVLENLVLDEKDNKEIEEIRNSLGKKFCRRCEYCMPCAVGINIPLSFLC
                     EGYYTRYGLKEWAKEKYEVMDVKPTECIDCGLCESRCPYELPIREMLKTVVEKLG"
     gene            complement(6539..7375)
                     /locus_tag="ACGI5H_002669"
     CDS             complement(6539..7375)
                     /locus_tag="ACGI5H_002669"
                     /EC_number="3.1.21.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429666.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA];
                     GO_function: GO:0008833 - deoxyribonuclease IV
                     (phage-T4-induced) activity [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="deoxyribonuclease IV"
                     /protein_id="HFG9698367.1"
                     /translation="MIKLGTHLSIAKGFANAAETAVYIGANTFQFFSRNPRGGNAKEF
                     DEKDIIKFQEIRKENNFAPLLAHAPYTMNLGGTKDDVYEFATRVIDEDIRRMDSLGIE
                     YMCFHPGSHVGGGVDFGIDRIVKGLNNAIKGDENITILLETMSGKGTEIGFKFEQLKS
                     IIDKIEHKEKIGVCLDTCHIFSAGYDIVNDLDGVLEEFDKVIGIERLKTVHLNDSMMP
                     FGDKKDRHAPIGEGKIGLKALIDFMEHPSLKHLPFFLETPFDDEGHKRELKMIKEILS
                     SK"
     gene            complement(7863..8426)
                     /locus_tag="ACGI5H_002670"
     CDS             complement(7863..8426)
                     /locus_tag="ACGI5H_002670"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417965.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HFG9698368.1"
                     /translation="MKEVLVLRDLECIKAIAHPRRIDILKAFDKSPLSAKQLSQLLEE
                     PHAKINYHIKMLYKVGILELVEEKIKSGIVEKYYYPSAKNVVIGNRILNFSLDNGEEK
                     EELYISKFENMSEVFYKAAEEDVLENENIVDYHDISLTHDELVELSDTMKSKIDEILN
                     KRQHNVEGSKYDIAMVIVPTLEEECPS"
     gene            complement(8524..9453)
                     /gene="glsA"
                     /locus_tag="ACGI5H_002671"
     CDS             complement(8524..9453)
                     /gene="glsA"
                     /locus_tag="ACGI5H_002671"
                     /EC_number="3.5.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417962.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004359 - glutaminase activity [Evidence
                     IEA];
                     GO_process: GO:0006541 - glutamine metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glutaminase A"
                     /protein_id="HFG9698369.1"
                     /translation="MNTLDETLLKEIISSNKKYTNYGQVASYIPELKNARRNDLGICI
                     IDSENNLYSAGNCSTKFTIQSISKPIVLAMALMDNDWEDVFSNVGMEPSGDPFNSIMK
                     LEINDTKKPCNPMINAGAIVTTSLINGSCLEEKEERMLSFFRKLAKNDNIGINYDVYK
                     SEKMTGDRNRAMAYLLKSDGFIRGNVEDVLDLYFKQCSIEIDSVDLARIGINLANYGV
                     DIENGEHLMSEMVSRIVKTFMMTCGMYDASGEFAIKVGIPAKSGVGGGIMASVPGRMG
                     IGVYGPALDKKGNSVAGVKVLEELSNKLKLNIF"
     gene            complement(10323..11990)
                     /locus_tag="ACGI5H_002672"
     CDS             complement(10323..11990)
                     /locus_tag="ACGI5H_002672"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425132.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside kinase"
                     /protein_id="HFG9698370.1"
                     /translation="MKKINLKIEGKDKEYSLEENSPGIRLGDIAKEFCDEHKGYITLA
                     VVDNKLKELNCRVKKDCEINFLDTTNEDGERVYFRVMSFIFVMACREIFWDSRVTIEH
                     SLSDGLYCEVHIDRKLKEADVENIKNKMKEIVNNDYVIEKIEVTRNEAISIFENNEMY
                     EKAELLKYKEYDSAKVYKCRNYIDHFYGYMLPSTGYIKSFDIKLYNGGVIILGPSEED
                     KTLPMKFVPQPKLSSVYYEAEEWSRLMGIDKVVSLNKIIENNEYGDIIRTFEALHEKK
                     LSQIADMIKDGNKRVVLIAAPSSSGKTSFAHRLSIHLRVNNLNPISISLDDYFIDRKH
                     TPLDEYGNYDFESIYAIDLEKFNLDLKKLLAGEEIDDIRFNFKEGKREYTGKKIKIDS
                     NQPIILEGIHGLNPILTSSIPDEDKFKIYISALTQINLDDHNRIPTADLRMIRRIVRD
                     YNFRGYSADNTILQWASVRRGEKKNIFPYQEEADAIFNSACVYELAVLKRFAKPLLEE
                     IKEDNPAHIEATRLLKFLQYFVELDDTSDIPGISILREFIGGSKIVD"
     gene            complement(12064..12819)
                     /locus_tag="ACGI5H_002673"
     CDS             complement(12064..12819)
                     /locus_tag="ACGI5H_002673"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860855.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIM barrel protein"
                     /protein_id="HFG9698371.1"
                     /translation="MAVGIASLLFNIEEALNICESIKQITHLEIGIDNISECSELCKY
                     KERISKLGLSIGIHLPMELNTCENIEYIRNSWINFIEKIEFELKGFDLRYFNLHLGYV
                     MTNRVRKNRDKYLGNSVDFLDKLNTNSYVCIENTYSKGGDFSNIGNISYDFEYIFKRI
                     KNSKICFCYDTGHCLIDEDAYVKNLKDKIRLIHLSDNDGINDTHVGIGRGILSEEGIK
                     EILTLDAEYLVLEINYEDIEDTISKLNNIVGEG"
     gene            complement(12829..13365)
                     /gene="lepB"
                     /locus_tag="ACGI5H_002674"
     CDS             complement(12829..13365)
                     /gene="lepB"
                     /locus_tag="ACGI5H_002674"
                     /EC_number="3.4.21.89"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417934.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0004252 - serine-type endopeptidase
                     activity [Evidence IEA];
                     GO_process: GO:0006465 - signal peptide processing
                     [Evidence IEA];
                     GO_process: GO:0009306 - protein secretion [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="signal peptidase I"
                     /protein_id="HFG9698372.1"
                     /translation="MNETIKEEIVEWIKIIITALFFAFIITRFIKPTLVNGESMYPTL
                     KSHDYLVANRMTYKLSEPKCGDIMIFKTDLLQENGRKKELVKRVIGVPGDHLKIKDSK
                     VYINGKLLNEVSYIHDNYTEGDIDMVIPKGKVFAMGDNREVSLDSRYKEVGLVDEENI
                     KGKVILRVFPFTDIGIFE"
     gene            complement(13531..14067)
                     /gene="lepB"
                     /locus_tag="ACGI5H_002675"
     CDS             complement(13531..14067)
                     /gene="lepB"
                     /locus_tag="ACGI5H_002675"
                     /EC_number="3.4.21.89"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417931.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0004252 - serine-type endopeptidase
                     activity [Evidence IEA];
                     GO_process: GO:0006465 - signal peptide processing
                     [Evidence IEA];
                     GO_process: GO:0009306 - protein secretion [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="signal peptidase I"
                     /protein_id="HFG9698373.1"
                     /translation="MGEAVKKEVVEWIKVIVIALVLAFAITRFIVPTIVKGESMYPTL
                     VERDYLIVNRIAYKVGEPKYKDIIVFKTDLTEENGKKKDLVKRVIGVPGDHVKIQDSK
                     VYVNDKLLDETSYIHNNRTDGDIDIVVPEGKLFAMGDNREKSLDSRYDEVGLVDEHTI
                     LGKVLVRLYPFSKIGTID"
     gene            complement(14167..15477)
                     /locus_tag="ACGI5H_002676"
     CDS             complement(14167..15477)
                     /locus_tag="ACGI5H_002676"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436985.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RsmF rRNA methyltransferase first C-terminal
                     domain-containing protein"
                     /protein_id="HFG9698374.1"
                     /translation="MTELPKEFLEDIEEILKDEYDDFIKSYEESKTTGLRINTLKIDK
                     KKLFDLELFDLNQIPWAEEGFYYDDKIDRPGRNPLHEAGAYYLQEPSAMSVIPKADIK
                     EGEKVLDMCAAPGGKSTYILSKLNDTGLLVSNEINASRIKALGENLERFGARNCIITN
                     TDSNSLRKTFNGYFDKVIIDAPCSGQGMFRKDEVAISDWSYAKVVECQSIQKEIIRDG
                     YKMLKKDGILIYSTCTFSREENEHVINEFISEYPHAELIEMERLWPHKIKGEGHFVAK
                     IKKLEEEECNVKELKIKNLDKEIKDYREFEKKFLKVDFYSNKKNKFYLRGENLYLLPE
                     IYPDTKKLKVLRYGLHLGVLKKNRFEPSHALSHYLKVEDVKNVENFSVQSESILKYLK
                     GDVVNSNDSRGWVLVSVEGIPLGWGKESSGVIKNHYPKGLRKVF"
     gene            complement(15556..16272)
                     /locus_tag="ACGI5H_002677"
     CDS             complement(15556..16272)
                     /locus_tag="ACGI5H_002677"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009901989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PrsW family intramembrane metalloprotease"
                     /protein_id="HFG9698375.1"
                     /translation="MKLDLFLLAIIPILIGMFWIRSKDRYCREPLIHLIKFFLIGAFL
                     SVIIILLENLLMKFNVFEGYSELIYVSFVVAGLVEEGVKALILIPALIKEKHFTEKLD
                     GIIYSVFLALGFATIENMVYIFSESRNLALQVGINRAVISIPAHVMFAITMGYYISKY
                     KFEGNKNKRREYLFMAVLIPILLHGVFDFILMIEYRWAIILLIVYVIILWKINLDKLE
                     KYMNHSKKVFFGNLRKKKKK"
     gene            16517..17788
                     /gene="sleC"
                     /locus_tag="ACGI5H_002678"
     CDS             16517..17788
                     /gene="sleC"
                     /locus_tag="ACGI5H_002678"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425119.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="spore cortex-lytic germination protein SleC"
                     /protein_id="HFG9698376.1"
                     /translation="MQDGFLTVSIIDATNNRPIQNAVVNIYSMSNGSQSSSTLYQNLR
                     SNESGQVTGLVLPAPDVDYSLQPSDVRPYSQYIVEAIADGYETVVIEGTQLLATIEAR
                     QGVPMSPRTRSKRSFSRQSELIFDIGEHTLYGTYPPKIPESNLKPLPPPTGFVVLDNP
                     VVPEFIVVHDGLPEDSSAPNYWIPFKEYIKNIASSEIYSTWPEQTIYANVIAIISFTL
                     NRVFTEWYRNKGYNFTITSTTAYDHKFINNRNLFEPINVVVDAIFNTFIKRPPTSRQP
                     LLAQYCDGQKSQCPDQMTQWGSKDLGDQGYDYESILRYFYGDEIVFERAPIVSGVPVS
                     FPGTTLQVGSSGQYVRTIQNQLNAISNSYPAVPKVIEDGIYGTDTENAVKIFQGIFGL
                     PQSGVVDFKTWYEISRVYVATTRIASLNPLI"
     gene            complement(18214..18870)
                     /locus_tag="ACGI5H_002679"
     CDS             complement(18214..18870)
                     /locus_tag="ACGI5H_002679"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417924.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9698377.1"
                     /translation="MKKGDFIWSGVLICIIAVLAIPSSREVFMEATGAHPYIGGFLKF
                     AVLATMGDLLGVRILYKDWKIPVGVFYRAIVWGIIGVVTTYGMSIYSSGVGQAQVDGM
                     LPFEGIAFANALFKSATMNILMSPTVFLFHKVMDCFIDKKYEVGKGIKVKLKDVVNIV
                     DWNAYLGFSVLKTIPFFWIPCHTIVFLFPAEYRVIASAFASIALGLILALANKSKVAV
                     "
     gene            complement(19982..20392)
                     /locus_tag="ACGI5H_002680"
     CDS             complement(19982..20392)
                     /locus_tag="ACGI5H_002680"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439126.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9698378.1"
                     /translation="MKIKKSLISAMMVSAMVLGGTGAVFANGNDSSNIALPKFESLIK
                     SGITDPTELEKYGVEHYTYEEYAKHIQELKDYAKDPNAVKDVSQKDLEETIKKMEQEL
                     EKIKTEGLKIMKPITIENEDGSQISIAYNYAAID"
     gene            complement(20608..21990)
                     /locus_tag="ACGI5H_002681"
     CDS             complement(20608..21990)
                     /locus_tag="ACGI5H_002681"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M56 family metallopeptidase"
                     /protein_id="HFG9698379.1"
                     /translation="MFIKLLEMSFTSGVLLLIVIFIRACLFKKLPKKVFVLLWLIVLF
                     KLLIPVSLNSGFSIYSIIESTFDVELGNTSTENYTLKKASDSTGKNNSDEFEIMSNIE
                     NIMMLEMLGILSFIVTIMFSILLCFRYFKIINLFKTSIHIKNHEFIKKWMCKNSRFRR
                     FIVCISEFTRTPLTSGILKPRIILPKQMNYANNQTLDFVLTHEMVHINSFDNLLKLFM
                     LVALVVHWFNPLVWVMFFLLNKDIEFSCDEKVMSILGEEYRADYATTLISLAEENNPF
                     SMTICSGFGKTKIEKRIVNIMKFKKSTYVTFLVSTVLVCGTGLVFATENKEINEVESF
                     GLTKNEQSDKIGFSISSKSTDLYSPKVESDILVSKAKSDGETHFSTAKVSVIEFREHE
                     ESSMSKVTNSENSEETYVNKSSNSKDVLYTDSGEVSIERSGYNDNRFVILRKGNLLAV
                     NKEQYRTWIE"
     gene            complement(22001..22360)
                     /locus_tag="ACGI5H_002682"
     CDS             complement(22001..22360)
                     /locus_tag="ACGI5H_002682"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888340.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0045892 - negative regulation of
                     DNA-templated transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="BlaI/MecI/CopY family transcriptional regulator"
                     /protein_id="HFG9698380.1"
                     /translation="MEIKLFDSELKVMEVLWERGESKAGELVKILKEETGWNRNTTYT
                     VIKKLVSKGAIERIEPNFVCKALISKEEVQKQETETLINKMFGGSSEKFLSAFINKEN
                     LSSDEITKLKQIVEKLK"
     gene            complement(22565..23344)
                     /locus_tag="ACGI5H_002683"
     CDS             complement(22565..23344)
                     /locus_tag="ACGI5H_002683"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF975 family protein"
                     /protein_id="HFG9698381.1"
                     /translation="MVSRQELKRVSKAQLSGNWGICAISMAVYIALIVLISIVGLPFE
                     PLTTIVVAVIAFCVSAGFTCMFLKITKDEKVKIGDIFVSGRIYLRSFGFYLFESIIVY
                     IYSFIITIIGAFLSFGVLLTSGAIEYLSSDNVGIGTIISTGITLVLIILVLMLPVYIL
                     LLYVSQATFLICEDKDNMGVFKSMGASLDMMKGNVLKLFVLNFSFIGWYILSIATLGI
                     GLLWLIPYVGVTNCNFYRQLVKENPDVEDILLDKEKSYTMY"
BASE COUNT         7864 a         4305 c         2207 g         9262 t
ORIGIN      
        1 attccttttt tatttatctc ttccttctca attatatttt tcttatccat tcctttttta
       61 tttatctctt cttccaaaat tacatctttt tcatttatct cttttagatt tacatttttc
      121 ataattatcc cccttcaaaa taccaattta taaaacgcta tttataaata gtttaatcat
      181 atcaacaaaa aaataaacat caatatataa aacatacaaa ataagaattt aatttatata
      241 tatttacaaa aaaagcaaaa acctattaaa gttcttgctt tttattatac ataaataccc
      301 attaaattct ataataaact tattcttttg acacagtttg tatcttgctg aaagatatta
      361 atttttcttt taccaatttc tttatttctt caaatttaac atctgtcaat atctctatag
      421 cctcttctac tctttcaaca gtatatatct taaattttcc atctcgcact gcatcattaa
      481 cttcatctga taaaacgaga tttctttgat tttttctagg aattatgacg ccttgctcac
      541 catttaaccc tttagtttta catatagaat aaaatccttc tatcttttca cttataccac
      601 caactacttg tatatcaccc ttttgattta tagaacctgt aacagcaata ttttgtttaa
      661 ttgatactcc actaagagat gataatagta catataattc tgcagaagat gcactatctc
      721 catctattcc accataattt tgttcaaaac aaacatatgc atttagtgac aatagtaaat
      781 cctgtgcaaa attctcagaa agatagccac ctaatataag tactcctttg ttatgtatag
      841 agccactcat atttacttct ctttctatat ttactatgcc tttacttcct gggctagtgg
      901 tcgctgtaat ccttgaagct ctaccaaaag agtattctcc tgtacttaag actgacaaac
      961 catttatcac tcctactttt cttccctctg tttctattag agtaaatcca ttttcaattg
     1021 attcatccat atgtgtttcc actctattga ttctttttct cttttcactt attgcttttt
     1081 taacatcaca ctgctctgta tactccgaat ttctaaactc tgcataagca cttccttcta
     1141 ttacaacttc cattatttta ttaaacttag ttgataattt ttctaaatca ccagataatc
     1201 tagtgctaaa tttaataacc tcttcaactg ctgatttagt aaaatgcctt aaattattct
     1261 tatcacattg gtatgctata aatcttgcta ttccttcttc attatcttca tttttatcca
     1321 tttcactatc aaagtctaca aatactttaa aatatttttc aaaatcttca tcatatctat
     1381 ataaaatatc atatatatag tggcttccaa tcagtactaa tttaacatcc aatggcatat
     1441 tttctggttt aattgctgtt tgtgtttcca atattacttt tttagtctgc aaagtctttt
     1501 taagaatttc ccaagacatt gtatatttta gtaattggtc tgcataaagt actaaataac
     1561 caccattagc cctatgaaat gctcctgata atagttttgt gaaatcagtc tttatatttc
     1621 catttgcata atcatactct gcctttccaa atagatttgc tggacttggg tttatctcta
     1681 ctacaacagg tgctgattct ttattctttg agcttccatt gtctacaaat aggttaattt
     1741 tatatttaat aaaatgctct ttatcatact tatcttttaa ctcctcttca tctaaataga
     1801 ataaatacat atattctatt atatctttct ttatattttc cagataagtt tgaatcttat
     1861 cataattttc atatttttca cacaatctct tgatatgagg ttctactaca agtttagcta
     1921 tctcttcttc aagctctaac actgcttttt cagctatttc ttctaagttt ctaattttat
     1981 atacgacctg tatcgccata ttttctagtt ctcttttagc tttgtaaaac tcttcatcag
     2041 actcatcact ttcatcttcc tcttctttca aagggataaa aactattccc attttactct
     2101 gttttaattt aaatcctttt tcttctccat attttttaat ttgcttcaaa agcatatctt
     2161 tttctatttc atattcatcc agaagtttat ttttttctat ttcaaaattt tcactttcaa
     2221 acgcattttt aaaatcttct aaaagacttt caattaattt ctccatatct ttcttaagtt
     2281 ctcttccaaa ccccttttct aattcaacta taataggctc tctagggttt tcaaaattat
     2341 atatataaca ccaatcttta tgcgtatttt ttttggatgc atactcattt aaaaccttta
     2401 aggcataagt acttttacca gttccaggtt caccagctat atatatgttg tacgctggat
     2461 tatttatttt caaccctaat tccatagctt ctacagctct ttcttgaccc aatatataat
     2521 ctagtggatt tatttcagat gtattattat atttcaatat tcccccacct ccccatattt
     2581 aactttaatg atataatatg acttttacac aacaagtgtt aaagtaaata cacattaaag
     2641 tatatgaaac agactcttat tattagtcat catacttatc taaaattatt tccatatttc
     2701 tctttattat atttcttcct ctccagctaa aagctctatc tccatatttc cttttaaatt
     2761 ctttatttga aatattttgt atctcatcat aattcaaata atctattata ttttctttaa
     2821 attccaaaat atgagttgtt ggtatttcaa cattatgtgg acatacttct tgacaaatat
     2881 cgcatccaaa tacctttttg ccattcttta aaacaacttt ttctttctct gacaaatctc
     2941 cttttttttg agttatatat gataaacatt ttttggggtt catatcataa tttcccaata
     3001 tagcatttcc cggacaatat tttacacact ttccacattt aaaacaactt ttttctagtg
     3061 gtttatcttc ttcaaattta taattattta ctatataccc tataaatacg taagaaccat
     3121 attcatcagt tatgatatta ttatttattc caaaatatcc tattcctgat aaataagcta
     3181 aatacctgtc aactaatggt ccattatcag caaataactt gtatttaaaa tctgttactg
     3241 ttttagaaat ataatcacaa atttgttgta aaaagtcctt tactacaatg tgataatcct
     3301 ttccatgaca atattttgat aaatttgaat ttttattctt ttcttgtcta tttatatgat
     3361 atggaaatgc acagactatt atagagttag catccttcat tatatgtctt gggttaattc
     3421 tgttctcaat tattggttct tccataccag ttaaataacc tttttgttgt ctgtccttaa
     3481 gtatcttttc taaattatca tacttatcta cccctgctac tcctacacag tttaatccta
     3541 ttaaattaca aaatgctttt aattccttat tatccataaa attattcctt tttaatctaa
     3601 ttgacttttt aaatttattt aattttttta gtctttttaa ccttttctag ctactaactc
     3661 ttttaaatac ttaatctttt tagctattca attttcttac ctacttaaat cttttagata
     3721 cttcgtcttt ttacctattt aattttttac ctactaacgc ttttagatac ttaatctttt
     3781 tatctattta gttttttacc tactaactct tttagatact tcatcttttt tatttactaa
     3841 ctcttttaga tacttcgtct ttttcattta cttatttaac ttttttatct acttaactcc
     3901 tttaaataat tagtcttttt atctatttaa ttattttacc tactaactct tttgaatact
     3961 tagtcttttt tatttattta atttttttat ctactaacgc ttttagatac ttaatctttt
     4021 tatctattta atttttttat ctactaactc ctttatatac ttagcctttt tcatttactt
     4081 atttaactac taactctttt agatacttag cctttttcat ttacttattt aactttttta
     4141 cctacttaac tcttttagat acttagcctt tttaatctat tcaacctttt ttacccactt
     4201 aaccttctta ccttttaata taaactctaa aacttcaaat atcattagtt atattttgac
     4261 attctttcta tagttaagca aaaagattga ttttttctta taattaatat cccatttaca
     4321 ttgccattta ttaaatcttt acttgactta tatggatttc tttttactct ctttactaaa
     4381 ctatacttat taatattatg aaggtcttat aatagactaa tatgaatatg tccatcatat
     4441 atcaaatttt aaaatttgta agcaaaatac ttatcttata ttactacatc taaagtggaa
     4501 aattttacaa aaaagctctg taaaaacact ttaaataaca atttgctttt aaatcatata
     4561 cagattataa taaatactgt ataaggatgg tgaaaaattt gattaaaata acaattccag
     4621 gtagacctat tagtaaatct aattttaagc ttcataacat aaatggtcaa gcatggatgc
     4681 cttcaaaggg aaaatattct aagtatcttg catacgaaaa catgattgca ggttttataa
     4741 accaacagta tcaaggggaa actgtcgaag aaaatctaat aacagtcttg aaattattct
     4801 tcccaaataa gagaatgggg gatttacata attatccaaa aagtatttgt gatggtattg
     4861 aaaaaagtgg aataataaaa aatgataaac aacttaagcc agtactttta tttgatttta
     4921 tagataaaga taaccctagg gttgaaattg aactttatcc agtatctaaa tacgatatat
     4981 cctataatat ttttgaaaaa taaagatttt atgtgttatt cgacattata ttgatactcc
     5041 agtatttgaa actatactaa tacaacaata ataattgtgt tatgtctata ctcaaacaaa
     5101 tgtttttaaa aagcattaag taaatattta ataagtatta aacaaatatt aaatttatat
     5161 aatagctata actatgtaaa tttaatattt gtatataaga ccacatctaa taaaaagaaa
     5221 tcggagtaaa tttaatacac cgatttcaat aaataaaatc tatcctagct tttcaacaac
     5281 agtcttaagc atttctctta taggaagttc atatggacat ctactctcgc aaagcccaca
     5341 gtcaatacac tcagtaggtt taacatccat aacctcatat ttttctttag cccactcttt
     5401 taatccatat ctagtataat aaccttcaca taaaaaactc aatggtatat ttattcctac
     5461 agcacaaggc atacaatatt cgcatcttct acagaatttt ttacctaaag aatttcttat
     5521 ttcttcaatt tccttattat ctttttcatc tagcacaaga ttttcaagta cagcgacatt
     5581 ttgtctaacc tgttcaacac tctccatacc tggtataact acatctatgt actctttaga
     5641 tagtatatat ttaatagcca gtgttgcatt gtctaaagca cctccagcta aaggtttcat
     5701 tactattatc ccaattcctt tttcatgagc ttttttaaac acttcatctg cttgtccttc
     5761 aactatatta taagggaatt gtatagtgtc aaattttcca tcttctatag ctttttctat
     5821 agtatttaaa ttgtgactag ttataccaat atgttttatc ttaccttgct cctttgcctc
     5881 taaaagggca ctataagcca ttttatcttt aaaaagatta tcatactcct cttctttaac
     5941 attatggaat tgatataaat ctataaaatc agttttaaaa ttatttaaac ttatttcaac
     6001 atctctcttc attgaatcat aatctctgga catactttta gtagctaaga aaaatttatc
     6061 tctttttcct tcaatggcaa ttccgattgc ttcctcactt attgtatacc ctcttgcact
     6121 gtcaataaag tttattcctt gtttttctaa ctcatttata actaagttag tatcatcttg
     6181 agtaatcctt tgtattggaa tgcccccaaa gccaactctc tttattttca tgttagtatt
     6241 gcctaaattt ctcatatctt tccccaccta acttttaata attttttata taatataaat
     6301 atgtcacctt taattataca acaaattatg agaatctttg caatgtattt acatactatt
     6361 cataatataa ttatatttta tatcagtcta ttcataatat aatcatactt tatacccagt
     6421 taatttgtat acaattttcg ttattcctat ccattaattt aaattatcac atttcatgat
     6481 tgtatctcca ccctaattat gttgagggtg gagtatttca catattttta ataaaggttt
     6541 atttactaga tagtatttct tttatcattt taagctctct cttgtgacct tcatcatcaa
     6601 aaggagtttc taagaaaaat ggtaaatgtt ttagactagg atgttccata aaatcaatta
     6661 atgcttttaa tcctatcttt ccttccccta taggagcatg tctgtctttt ttgtctccaa
     6721 atggcatcat actatcattt agatggacag ttttcaatct ttctatgcct ataaccttat
     6781 caaattcttc caaaacccca tctaaatcat tcactatatc ataaccagct gaaaaaatat
     6841 gacatgtatc aagacacaca cctatttttt ctttatgctc aattttgtct attatacttt
     6901 ttaattgctc aaatttaaaa cctatttcag ttccctttcc cgacatagtt tcaagaagta
     6961 tagttatatt ttcatcaccc tttatggcat tgttcaatcc ttttactatt ctatctatgc
     7021 caaaatctac accaccacct acatgacttc caggatgaaa acacatgtat tcaattccta
     7081 atgagtccat ccttcttata tcctcatcta tcacccttgt tgcaaattcg tatacatcat
     7141 cctttgtacc acccagattc atagtatatg gtgcatgtgc aagcagtggt gcaaaattat
     7201 tttcttttct aatttcttga aatttaatta tatctttttc atcaaattct ttagcatttc
     7261 ctcctcttgg atttctacta aaaaattgaa atgtatttgc accaatatat acagctgtct
     7321 cagccgcatt agcaaatcct tttgctattg aaagatgtgt tcctaattta atcatattaa
     7381 tctcctttta tttgtactac tacttgtact caattttaat tttgaactac tccaccttaa
     7441 ctacatttag ccaacatatg aagatggaga ttcctatttg atagtacttt ttcactaaaa
     7501 attcgtaagc tctaagggat gttctatccc aactaatctc attcctcttt taacatattt
     7561 ctagcattga tttaatttat attaattttt aattttaata tttacacttt aattataccc
     7621 attttaatca atttcaaata ttataatctt acatactttg tatattatct aagcacttct
     7681 tagatagtgt atacatctta cactatacat attatttaca aatacaatag gtataaaaaa
     7741 acaaaaaaat agagattaaa aatcattgtt ttacccatac caaaaactat tttttgatta
     7801 ttaagtaaat tttgatgttc aatctctaat attatatctt taattaatcc ataattaatt
     7861 ctctaactag gacattcctc ctcaagagta ggaactataa ccatagctat atcatactta
     7921 gaaccttcaa cattgtgttg tcttttattt aaaatttcat ctatctttga cttcatagtg
     7981 tcactaagtt caactaattc atcatgagta agagaaatat catgataatc aactatattt
     8041 tcattttcta aaacatcttc ctctgctgcc ttataaaaaa cttcactcat attttcaaat
     8101 tttgatatgt acaattcttc tttttcttcc ccattgtcta aagaaaaatt aagtatccta
     8161 ttccctataa ccacattttt tgcacttgga taatagtact tttccacaat ccccgacttt
     8221 attttttcct caactaattc taaaatacca actttgtata acatttttat atggtagttt
     8281 atttttgcat gaggttcttc caataattga gataattgtt ttgctgacaa tggcgatttg
     8341 tcaaatgctt ttagaatatc tattctacgt ggatgcgcaa tagcctttat gcactccaaa
     8401 tctcgtaata ccaatacctc tttcattgac ccctcctaaa aaatttattt aattcatatt
     8461 tctttacaat ttaattatat attaaattat atgttgttgt caaaaaaatc ctttcttaat
     8521 attttaaaaa atatttaatt tgagtttatt tgacaactcc tctaaaactt taactcctgc
     8581 gacgctgtta ccttttttgt caagcgcagg tccataaaca ccaatcccca tgcgtcccgg
     8641 cacagaagcc attataccac ccccaactcc agattttgca ggaatgccaa ctttaatagc
     8701 aaattcccca gaagcatcat acattccaca agtcatcata aatgtcttga caatcctaga
     8761 aaccatttca ctcattaaat gctcaccatt ttctatatct actccataat ttgcaagatt
     8821 tattccaatt ctcgctaaat ctacagaatc tatctcaatt gagcattgtt taaaataaag
     8881 gtctagaaca tcttctacat tccctctgat aaatccatca cttttcaata agtaagccat
     8941 agctctgttt ctatctccag tcattttttc agacttatag acatcatagt ttattcctat
     9001 attatcattt tttgctaact ttctaaagaa actaagcatt ctttcttctt tttcttctaa
     9061 acaactccca tttataaggg aagtggttac tatagcccct gcatttatca ttggattaca
     9121 gggttttttt gtgtcattaa tttcaagttt cattattgaa ttaaatgggt ccccacttgg
     9181 ctccattcca acgtttgaaa aaacgtcttc ccaatcatta tccataagtg ccatagcaag
     9241 cacaattggt tttgaaatac tttgtatagt aaactttgtg ctacagtttc cagcactata
     9301 aagattattt tcgctatcta tgatacaaat tcctaaatca tttcttctag cgttttttaa
     9361 ttctggtatg taactagcga cttgtccata attagtatac ttcttattag aacttataat
     9421 ttcttttaat aatgtctcat ctaacgtatt catatgcacc tcttatatta tgttatatat
     9481 tctattttag cacaagttta tactataata aaacaatgtt aaaaaaaatt atactttaaa
     9541 attattttct acaagaatca attcattttt caaacaattt aaatagttta aatagcttaa
     9601 taatttaata atttaacaac ctagcaattt agtaatctaa taatccagta atttaacaac
     9661 ctaataattt agcaatctaa taatctaact atctaataat ccagtaactt aacaacctag
     9721 taatttagta attcaacaat ctaacaattc aataatttaa caatttaaca acctagtaat
     9781 ctaactatct aataatccag taacttaaca acctagtaat ttagtaattc aacaatctaa
     9841 taattcaata atttaacaac ctagtaatct aactatctaa ataatccagt aacttaacaa
     9901 cctagtaatt tagtaattca acaacctaat aattcaataa tttaacaacc tagtaattta
     9961 gcaatccagc aatctaataa tccagtaatt taaattttta taacaccaaa aatttctaac
    10021 ccaacacctt ttactctttt actcttttac tcttttactc ttttactctt ttactctttt
    10081 actcttttac tcttttaaaa aataatcaca taaattaaca aaatattaaa caaaaaagta
    10141 aaatttaaaa taaaaagctt gcttcataca aaagtataaa acaagccttt ttatatatca
    10201 actcaaactt taaaatctgt atcaatttaa ttctccactt tacacttaat atacttaaca
    10261 taaaccaata acactacttg ctatgccatt taatcttcat aaaacaatct ataatacaca
    10321 cattaatcaa ctattttact tcctccaata aattccctaa gaattgaaat acctggtatg
    10381 tcagaagtat cgtccaattc aacaaaatac tgcaaaaact ttagtaatct agtagcttca
    10441 atatgtgcag gattatcttc ctttatctct tccaacaaag gtttcgcaaa tcgttttaaa
    10501 actgccaatt catatacaca agcagagtta aatatagcat ctgcctcctc ttggtacggg
    10561 aatatattct tcttttctcc tcttctaact gatgcccatt gtaaaatagt attatcagca
    10621 ctatatcctc taaaattata gtctctaaca attcttctta tcattctcaa atcagcagta
    10681 gggattcgat tatggtcatc caaatttatt tgagtaaggg cacttatgta tatcttaaat
    10741 ttatcttcat ctggtataga tgatgttaaa ataggattta gcccatgtat accttctaat
    10801 ataattggct gatttgaatc tatctttatc tttttaccag tgtattctct cttaccttct
    10861 ttaaaattga atcttatatc atcaatttct tcaccagcta aaagtttctt taagtctaag
    10921 ttaaacttct ctaaatctat tgcataaatt gattcaaaat cataatttcc atattcatct
    10981 aaaggagtat gttttctatc tataaaataa tcatctaaag aaattgaaat aggatttaaa
    11041 ttatttactc taagatgtat tgataatctg tgagcaaaac ttgtttttcc agatgaagat
    11101 ggagctgcta ttaaaactac tctcttattg ccatccttta tcatatccgc tatttgggat
    11161 aacttctttt catgcaatgc ttcaaatgtc cttattatat ctccatattc attgttttct
    11221 attattttat taagagatac taccttgtca attcccataa gtcttgacca ttcttctgct
    11281 tcataatata cacttgatag cttaggttga ggtacaaatt tcataggaag agtcttatct
    11341 tcttcactag gtcctaaaat tataacgcct ccattataaa gcttaatatc aaatgatttt
    11401 atataaccag ttgatggcaa catataacca taaaaatggt ctatatagtt tctacactta
    11461 tatactttag cactatcata ctctttgtat ttcaaaagct ctgccttttc atacatttca
    11521 ttattttcaa agatagaaat agcttcattt cttgtaactt caattttttc tataacataa
    11581 tcgttgttta ctatctcttt catcttgttt tttatatttt caacatctgc ttctttaagc
    11641 tttctatcta tatgaacttc acaatatagc ccatctgata gtgaatgttc tattgtaact
    11701 ctgctatccc aaaagatttc tctacatgcc attacaaata taaatgacat gactctaaag
    11761 taaactctct ctccatcttc attagtagta tctaaaaaat ttatctcaca atccttctta
    11821 actctacaat ttagctcttt tagtttattg tctacaactg caagtgttat ataaccctta
    11881 tgctcatcac aaaattcttt tgctatatct cccaatctga ttccagggga attttcttct
    11941 aatgaatatt ccttatcttt tccttctatt tttaagttta tttttttcac ttcaacatct
    12001 ccttcctttt gatgaatata aattttaatt aatgaggcat atcaacaaga taaagagagg
    12061 tatttaaccc tctcctacaa tattattcaa tttacttata gtatcttcaa tgtcttcgta
    12121 atttatttct aatactaaat attctgcatc taatgttaag atctctttaa tcccctcttc
    12181 agataaaatt cctcttccta taccaacatg tgtatcattg ataccatcat tatcacttaa
    12241 gtgtatcagt cttattttat cctttaagtt ctttacataa gcatcctcat caattaaaca
    12301 gtgtccagta tcgtaacaaa aacaaatctt agaattttta atcctcttaa atatatattc
    12361 aaaatcataa gatatatttc caatatttga aaaatcccca ccttttgaat aagtattctc
    12421 tatacataca tatgaatttg tatttaattt atctaaaaaa tccacactat ttcctaaata
    12481 tttgtctcta ttctttctaa ctctatttgt cataacatat cccaaatgaa ggttaaaata
    12541 ccttaaatca aatcctttta gttcaaattc tatcttctca ataaaattta tccatgaatt
    12601 tcgtatatac tctatgtttt cgcaagtatt taattccata ggcaaatgta tccctataga
    12661 taatcctaac ttagaaattc tctctttata tttacataac tcactacatt cagatatatt
    12721 gtcaattcca atctctaaat gagttatttg ctttatactc tcacaaatgt ttaaagcctc
    12781 ctcaatatta aacaataagg acgctatacc aactgccata caaatcacct actcaaaaat
    12841 acctatatct gtaaaaggaa atactcttaa aataactttt cctttaatat tttcttcatc
    12901 tactaatccc acttctttat atctactgtc taaactaact tctctattgt ctcccatcgc
    12961 aaatactttt cccttaggaa tcaccatatc aatatcgcct tcagtataat tatcatgtat
    13021 atatgaaact tcatttaata acttaccatt tatataaacc ttagaatcct taatttttag
    13081 atggtcacca ggaacaccta taaccctttt tacaagctct tttttccttc cattctcttg
    13141 taataaatca gtcttaaata tcattatatc tccacatttt ggttctgata acttatatgt
    13201 catcctgttt gctaccaaat aatcatgtga tttaagtgtt gggtacattg attctccatt
    13261 tactaatgtt ggttttataa aacgagttat aataaatgca aaaaaaagtg cagtaataat
    13321 tatttttatc cactctacaa tctcttcttt aatagtttca ttcattcaca aattctcctt
    13381 tatagttata ttatctttat tgataatgtc tcttaaacac tatcttttag ataagtctac
    13441 taaataaggt gttgtctttt ttatatagac aactattgtg tatggtctgg tgatttcagc
    13501 taatcagcga ttgctccaaa ttttatatgt ttagtcaata gttcctatct tagaaaatgg
    13561 atacaatctg actagaacct ttcctaaaat ggtatgctcg tcgaccaatc caacctcatc
    13621 gtatctacta tctaaacttt tttctctatt atctcccatt gcaaataatt ttccttctgg
    13681 aactacgata tcaatatctc catcagtacg attattatgt atataggaag tctcatctaa
    13741 caacttatca tttacatata ccttggagtc ttgtattttt acatggtcac caggaacccc
    13801 gataactctt tttactaaat cttttttctt tccattttcc tctgttaagt cggttttgaa
    13861 tactattata tctttgtatt ttggctctcc taccttgtac gcaattctgt taactatcaa
    13921 ataatcacgt tcaactaatg taggatacat tgattctcct ttgactattg ttggcactat
    13981 aaaacgagtt attgcaaatg ccaaaacaag agctatgaca atcactttta tccattctac
    14041 aacttctttt ttaactgctt cacccactaa aatcgtctcc tctgtgttaa atattaagtc
    14101 aatctacagc aaaataatct accataaacc tacaatataa atattatact tcttttttct
    14161 aatagtttaa aatacttttc taagaccttt aggataatga ttcttaatta caccagaaga
    14221 ttcttttccc caacctaaag gtattccttc aaccgaaacc aaaacccatc ctctactatc
    14281 attagaattt acaacatccc cttttaaata tttaagaatt gattcactct gtacactgaa
    14341 gttttcaaca ttttttacat cttcaacttt taagtaatga gatagtgcat gagaaggctc
    14401 aaatctattc ttctttaaaa cccctaaatg caaaccatat ctcaatactt ttagtttttt
    14461 cgtatctgga tatatttcag gaagtaggta caaattttct cctcttaaat aaaatttatt
    14521 ttttttatta ctataaaaat caacctttaa aaatttcttt tcaaactccc tataatcctt
    14581 tatttcttta tctaaatttt ttatttttaa ttctttgaca ttacattctt cttcttctaa
    14641 tttttttatt ttggcaacaa aatgaccttc tccctttatc ttatgaggcc ataatctttc
    14701 catttcaata agttctgcat gtggatattc actgataaac tcatttataa catgctcatt
    14761 ttcctccctt gaaaaagtac aagttgagta aattaaaatg ccatccttct ttaacatttt
    14821 atatccatct cttataatct ctttttggat ggattgacat tctactacct ttgcataact
    14881 ccaatctgat atggcaacct catccttcct aaacatacct tgcccagaac aaggtgcatc
    14941 tataataacc ttatcaaaat acccattaaa cgtctttctt aagctattag aatcggtgtt
    15001 tgttataata caatttctcg ctccaaatcg ctctaaattt tcccctagag ccttaattct
    15061 actagcatta atttcattag aaaccaataa acctgtatcg tttagcttag atagtatata
    15121 tgtagatttt ccaccaggag cagcacacat atcgagaact ttttcaccct ctttaatatc
    15181 tgcctttggt attacactca ttgcagaagg ctcttgcaaa tagtatgctc cagcctcatg
    15241 cagtggattt ctaccaggtc tgtcaatttt atcatcataa taaaaacctt cttctgccca
    15301 tggtatttga ttcaaatcaa acaactccaa atcaaataat tttttcttgt caatttttaa
    15361 agtatttatt ctaagcccag tagtcttact ttcctcataa ctttttataa aatcatcata
    15421 ttcatctttt agtatttctt caatatcttc taaaaattcc tttggtaatt ctgtcaaatc
    15481 tataatcccc cttcaatctg ctttacttgt gtgtcattta ttatacttta attatttatg
    15541 tctttccttt aaattttatt tcttcttctt tttcctaaga ttaccgaaaa acactttttt
    15601 agagtgattc atatatttct caagtttatc aagatttatc ttccacaaaa ttattacata
    15661 aactataagt aatataatag cccatctata ttctatcatc aatatgaaat caaaaactcc
    15721 atgtaataaa attggaatta acaccgccat aaacaaatac tcacgtcttt tatttttatt
    15781 tccctcaaat ttatacttag aaatatagta gcccatagta attgcaaaca ttacatgagc
    15841 tggtatagag ataactgccc tattaatacc aacttgcagt gctagatttc tactttcaga
    15901 aaaaatataa accatatttt caattgttgc aaatcctaaa gctaaaaata cagagtaaat
    15961 aataccatct aacttttcag taaagtgttt ttctttaatt agggcaggaa tcagtatcag
    16021 agcttttaca ccttcttcta caagtcctgc aactacaaat gatacatata ttagttctga
    16081 atacccttca aatacattaa acttcatcag taaattttct aaaagtataa ttataacact
    16141 tagaaaagca cctattaaaa aaaatttaat tagatggatt aggggttctc tacaatatct
    16201 atctttagac cttatccaaa acatccctat caatatagga attattgcta ataaaaataa
    16261 atctagcttc atagattatt ttcctttcaa aatttttgat ttatttatga tttatatcat
    16321 ctacttattt ttaacttatt cgtgttttaa atacatacta aaatatacat taaattattt
    16381 taaattattt aaatacaaat atactcaaat actcaaaaaa atttaaattt atatctatat
    16441 tatttaacaa atttcaagct atattcatat cttgaaatat aagggaacta aattcattta
    16501 aagaaagggt gatttgatgc aagatggttt cttaacagta agcataattg atgctactaa
    16561 caatagacct attcaaaatg cagtagtaaa catatattca atgtctaatg gtagccaaag
    16621 ctcatcaact ttataccaaa acctaagaag taatgaatct ggtcaagtga ctggtttagt
    16681 attaccagca ccagatgtag attactctct acaaccatct gatgttagac cttatagcca
    16741 gtatatagtg gaagccatag cagatggata tgagacagtt gtcatagaag gaacacagtt
    16801 gttagctaca attgaagcaa gacaaggagt tcccatgtct cctagaacaa gaagtaagcg
    16861 ttctttctca agacaaagtg agttgatttt tgatatagga gaacatactc tatatggtac
    16921 ttatcctcct aagattccag aaagtaactt aaaaccatta ccacctccta ctggtttcgt
    16981 tgtattagat aaccccgtag tgcctgaatt tatagtagtt catgatggtt tgccagaaga
    17041 ttcatcagct ccaaactatt ggattccatt taaagagtac attaaaaaca tagcgtcatc
    17101 tgaaatatat tcaacttggc ctgaacagac aatctatgca aatgtaatag ctataatatc
    17161 atttacttta aatagagtct ttactgaatg gtatagaaat aaaggatata actttacaat
    17221 aacttcaaca acagcatacg accataagtt tataaataat agaaacttat ttgaaccaat
    17281 taacgtagtt gtagatgcta tttttaatac ttttataaaa agacctccta catcaagaca
    17341 gccactatta gcacaatatt gtgatggaca aaaatcccaa tgtcctgacc aaatgactca
    17401 atggggcagt aaagacttag gtgaccaagg atatgactat gagagtatac taagatattt
    17461 ctatggagat gagatagtat ttgaaagagc acctatagta agtggtgtac cagtgtcatt
    17521 ccctggtact acactacaag ttggttcttc tgggcagtat gttagaacca tacaaaatca
    17581 gttaaatgct atatctaatt cttatccagc tgtaccaaaa gttatagaag atggtatcta
    17641 tggaacagat acagaaaacg ctgttaagat attccaagga atctttggtt tacctcaaag
    17701 cggagtagta gattttaaaa catggtatga aatatccaga gtttatgtag ctacaactag
    17761 aatagcttct ttaaatcctt taatttaaag cttgatttag aacataaact caaattattg
    17821 aataaaatta ttaatttaaa ataaaagtgg ctgttatgaa ctaatatata ccataagtat
    17881 tacttataag tattgtagtc ttaacagcca ttttttagtt ataacttgtt tttttagaat
    17941 cttaaaactt taaatggggg attttaagct tcttaaaaac agtgcttagc aacttagatt
    18001 tctttaaaat attatattta tttttaagtt taataaaatg ctattctaac gaaaaaccta
    18061 ctttttattt aaaatctcac ttattattta aaacactatc catcacttag aatattactt
    18121 cttatataaa ttattattta ttataaatac aaataatatt aatttaaaaa gttattccta
    18181 atttaaataa tactactatc ttcatcagtg aacctaaact gcaactttag acttattagc
    18241 taaagccaat attagaccta aagctataga tgcaaatgca gaagcaatta ctctatactc
    18301 agcagggaat aaaaatacaa ttgtatgaca tggtatccag aaaaatggta tagtttttaa
    18361 aacactaaaa ccaaggtaag cattccagtc cacaatattt accacatctt taagttttac
    18421 cttaatcccc tttccaacct catatttttt atctataaaa cagtccataa ccttatggaa
    18481 taaaaataca gttggtgaca ttagtatatt catagttgca ctcttaaata gagcatttgc
    18541 aaaagctatt ccctcaaatg gaagcatacc atccacttgt gcttgaccta cacctgatga
    18601 gtagattgac attccatatg tggtaactac acctattatt ccccaaacta ttgctctata
    18661 aaatactcct actggtattt tccaatcctt atacaaaatt ctaacaccaa gtaaatctcc
    18721 cattgtagct aatacagcaa actttaaaaa acctccaata tatggatgtg cacctgttgc
    18781 ttccataaat acttctctac tacttggtat tgctaagaca gcaataatac aaataagaac
    18841 tccactccat ataaaatcgc cttttttcat atttataaat actatttaat atataaatag
    18901 ttctcctttc tattaaagat ttatttaatt tacaatctat ctacaattat ttattaatca
    18961 cttattatta gatattcatt ttccatattt aaatttattc tatcccttta tctatttatt
    19021 ttcttactac tctatccacc attatctata tatttatttt acgattactc tttcacccta
    19081 accctttaac tatctatttt ttcttactat tcttatccac atcatccata tatttatttt
    19141 acgattactc tttcactcta accctttaac tatctatttt ttctgatatt cttatccacc
    19201 atcatccata tatttatttt acgattactc tttcacccta accctttaac tatctatttt
    19261 tttctggtat tcttatctac tattatctgt atatttattt tatgattact cttttaacct
    19321 accccctata ctttatagta atatgttttt aacctttttc attattccca atatgcttta
    19381 taactacaaa tactctcccc ccttaaaaat aataataaaa ttaatcaata aatttataat
    19441 catattatta ctctatgtat taagcaatta ctatgccaat aaactttgat ttttttaaac
    19501 aaatcttaaa aatcctaaaa tgctaatttt ctttaacttt taatgaatct aatagataac
    19561 atttaatttt cgttatattt ttcagaatat ttctattatt atttttaaga aaaaaaaata
    19621 atgttaacat ttcttaacat acattaaaaa atgttaacat tataaattgg gtttaatact
    19681 tttactttga ctcgatttac ttttattcta cttcttactt tatttttaac ttagacttta
    19741 tttttttatt acttatttga gtcttattta ttttattctc actccatatg ttcaattaca
    19801 tttgtctaaa ttctttgata cttttattac ataattttaa caagcttaag tgttatttgg
    19861 gtagtgcagt tgataattat ttaaataatc atcaactgca tgtttatatc attacagtag
    19921 cttaatgtat ttaatcatac ttacttagga ttttgaaata tcttagagat tatatttaac
    19981 attagtcaat tgctgcataa ttgtaagcaa ttgaaatttg agacccatct tcattttcta
    20041 tagtgatagg cttcataatt tttaatcctt cagtttttat cttttctaat tcttgttcca
    20101 ttttcttaat tgtttcctca aggtcttttt gacttacatc tttgactgca ttagggtctt
    20161 tagcatagtc ttttaattct tgaatatgtt tagcatactc ttcataagta taatgctcaa
    20221 caccatactt ttccaattca gtagggtcag ttattcctga ttttattaga gattcaaatt
    20281 taggtaaagc aatattagat gaatcatttc catttgcaaa tactgctcca gttcctccta
    20341 gtaccattgc agataccatc attgcactta taagggattt ttttattttc ataaccaatc
    20401 ttcctttctt agagatttat ttgggtagtg tagtttaaaa tgactattgc aatagttatc
    20461 aactacactc ttagactatc acagtagtca tgtttatgtc aagccttttt aaaaaacttt
    20521 tcaataaaaa atactatctc aaagcaaaat taattatttt gagatagtat tttaattcta
    20581 aatcttttat attactaaga tttatggtta ttctatccat gttctatatt gttctttatt
    20641 aactgctaac aaattccctt ttcttaatat gacaaagcga ttatcattat agccacttcg
    20701 ctcaattgaa acttctcctg aatcagtata aagtacatcc ttactattac tagatttatt
    20761 tacatacgtt tcttcactat tctcagaatt agttactttg ctcatagatg attcttcatg
    20821 ctctctaaat tcaattacag atacttttgc cgtactaaaa tgagtctctc catcactttt
    20881 agctttacta acaagaatat cagattctac tttgggagaa tataaatcag ttgatttact
    20941 acttattgaa aatccaattt tatcactttg ttcatttttt gttaaaccaa aagattcaac
    21001 ctcattaatc tctttatttt ctgttgcaaa aacaagacct gtcccacaaa ctaatacagt
    21061 tgaaactaaa aaagtaacat aagttgattt tttaaatttc ataatattaa ctattctctt
    21121 ttctattttt gtctttccaa atccactaca tattgtcatt gaaaatggat tattctcctc
    21181 tgctagactt attagtgtgg ttgcataatc agccctatat tcttcaccaa gtatactcat
    21241 aaccttttca tcacaactaa attctatgtc tttatttagt aaaaaaaaca tcacccaaac
    21301 taagggatta aaccaatgga caacaagagc tacaagcata aataacttta acagattatc
    21361 aaagctatta atatgaacca tttcatgagt taaaacaaag tctaaagttt gattattagc
    21421 ataattcatt tgctttggca aaataattcg tggttttaaa ataccagatg taagtggtgt
    21481 cctagtaaat tcagatatgc aaacaataaa tcttctaaaa cggctattct tacacatcca
    21541 ttttttaatg aactcatgat tttttatatg aattgaagtt ttaaaaagat taattatttt
    21601 aaaatatcta aagcataaaa gtatgctaaa cataatagta actataaaag acaaaatgcc
    21661 caacatttcc aacatcataa tattttcaat attagacatt atttcaaatt cgtcagaatt
    21721 gtttttacct gtagagtcac tagctttctt aagagtataa ttttctgttg atgtattacc
    21781 caattccaca tcaaaagtcg attcaattat actataaata ctaaaaccag aatttaaact
    21841 tactggtatt agaagtttaa ataaaacaat caaccacaat aatacaaata cctttttagg
    21901 taatttttta aataaacatg ctcttataaa aataactatt aaaagtaata ctccagaagt
    21961 aaaactcatt tctaacaatt taatgaacat aaatcttacc tcactttaat ttttcaacaa
    22021 tttgtttaag ttttgtaatc tcatcacttg aaagattttc tttattaata aaagctgaaa
    22081 gaaatttttc tgaagaccct ccaaacattt tattaattaa agtttctgtt tcctgttttt
    22141 gtacttcctc tttgcttatt aaagctttac aaacaaaatt cggctcaatt ctctctattg
    22201 caccttttga cactaatttt tttataacgg tatacgtagt gtttctattc catcctgttt
    22261 cttcttttaa aatttttact aactctccag ccttgctttc tcctctctcc catagaactt
    22321 ccattacttt aagttctgaa tcaaataatt ttatctccat ataaaatcgc tcctcaaata
    22381 tagttatcac aatagtcatt actataataa aaaactatca tagtagtcta tactatgtca
    22441 atcatttatt ttttaataat aaaaactgtc tttttaaaaa attcttataa aagacagttt
    22501 tatcaatgtt atactttaat gtttaattaa agccatattt tatttaaata tataactatc
    22561 tatcttagta catagtataa gatttttctt tatctaatag tatatcctct acatctgggt
    22621 tttcttttac taattgtcta taaaaattac aattagtaac acccacatat ggaattagcc
    22681 atagtagacc tattccaaga gtagctattg aaagtatata ccatcctata aagctaaagt
    22741 ttagtacaaa taatttaagt acatttcctt tcatcatatc taaactagca cccattgatt
    22801 taaatacacc catattatcc ttgtcttcac aaattaagaa agtagcttga gaaacatata
    22861 atagcaatat ataaactggt aacataagaa caagtattat aagaactaga gttattccag
    22921 tagaaataat agtccctatt ccaacattat cacttgataa atattcaatt gctccactag
    22981 taagtaaaac tccaaatgat aaaaacgctc ctataattgt gattataaaa gaataaatat
    23041 acacaataat tgattcaaat aaataaaaac caaaacttct taaataaatt ctcccactta
    23101 caaagatatc tcctatcttg actttttcat ctttagtaat tttcaagaac atacatgtaa
    23161 atcctgctga aacgcaaaaa gctattacag ccactacaat agtagtcaat ggttcaaaag
    23221 gtaatcctac aattgatatt aatactatca atgcaatata tactgccata gaaattgcac
    23281 atatccccca gtttccagat aactgagctt tagatactcg ttttaattct tgccttgata
    23341 ccataaaaaa cacccctttc attttataaa aaaactttta aaaatataaa taatctttta
    23401 acgtataata ttaatatatc atattttcga ctatataaga tacaattatt caccatgttt
    23461 tatcaagata tgccataatt gtattactag ttttatatag tcaacattac caaatacatc
    23521 aaataaattt gattaattat tcaacaagta ataaaataat ttctattaat tatactttat
    23581 ttagtaaaca aattatttaa taaaaaaatt acctaataca gtaaattaat tggtaaga
//
LOCUS       DAYAOO010000064        23143 bp    DNA     linear   BCT 12-OCT-2024
DEFINITION  TPA_asm: Clostridioides difficile isolate ST8-SSI-h139-18
            SAMN40601845-rid21577343.denovo.064, whole genome shotgun sequence.
ACCESSION   DAYAOO010000064 DAYAOO010000000
VERSION     DAYAOO010000064.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN40601845
            Sequence Read Archive: SRR28438827
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 23143)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 23143)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-MAY-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-MAY-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002157583.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002157583.1
            Genome Coverage       :: 163x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/11/2024 16:19:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 4,038
            CDSs (total)                      :: 3,963
            Genes (coding)                    :: 3,930
            CDSs (with protein)               :: 3,930
            Genes (RNA)                       :: 75
            rRNAs                             :: 6, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 60
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 33
            CDSs (without protein)            :: 33
            Pseudo Genes (ambiguous residues) :: 0 of 33
            Pseudo Genes (frameshifted)       :: 7 of 33
            Pseudo Genes (incomplete)         :: 25 of 33
            Pseudo Genes (internal stop)      :: 11 of 33
            Pseudo Genes (multiple problems)  :: 8 of 33
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..23143
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN40601845-rid21577343.denovo.064"
                     /isolate="ST8-SSI-h139-18"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Denmark"
                     /collection_date="2018"
                     /collected_by="Statens Serum Institute"
     gene            complement(247..423)
                     /locus_tag="ACGI5H_002684"
     CDS             complement(247..423)
                     /locus_tag="ACGI5H_002684"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9698382.1"
                     /translation="MFRDKMDRCTHMLTAYIGSSYDYCDFIDTQLDDFILEYGENVVE
                     SCLHQVMVLVSKYN"
     regulatory      complement(477..573)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF01051"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="cyclic di-GMP riboswitch class I; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /bound_moiety="cyclic di-GMP"
                     /db_xref="RFAM:RF01051"
     gene            1370..1771
                     /locus_tag="ACGI5H_002685"
     CDS             1370..1771
                     /locus_tag="ACGI5H_002685"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429137.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNHCP domain-containing protein"
                     /protein_id="HFG9698383.1"
                     /translation="MNYKNRKRAYYQENSCMDNFICKNCGCLVVPEGAGTQHRNHCPH
                     CLHSLHVDIIPGDRAADCDANMEPIGVWVRKNGEWAIIHRCTRCGHLSSNRIAADDNS
                     VKLMSIALKPLAQPPFPLERIIEKLEKEETE"
     gene            1834..2835
                     /gene="rsgA"
                     /locus_tag="ACGI5H_002686"
     CDS             1834..2835
                     /gene="rsgA"
                     /locus_tag="ACGI5H_002686"
                     /inference="COORDINATES: protein motif:HMM:TIGR00157.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003924 - GTPase activity [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_function: GO:0043022 - ribosome binding [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome small subunit-dependent GTPase A"
                     /protein_id="HFG9698384.1"
                     /translation="MEYHDLYLARIISQEKNFYQAVCVNGVLFAEVSGKLRFEATIQS
                     DFPTVGDFVMLDRCNNKNGNAIIHHVLHRKSLFVRKAAGKVNEEQVVAANIDIVFLCM
                     SLNKDFNIHRLERYLSLTWESGAIPVVVLTKSDLCDNVHRKLQVVNSIALGVDVVVTS
                     SIEPDGYKQISKYIKPGCTVALLGSSGVGKSSLINCLMGGEFLNTKEIRIDDDKGRHA
                     TTRRELFLISGGGIVIDTPGMRELGMWDVSEGLDKSFADIEAYFGKCHFRNCTHTSEP
                     GCAIWEAIAHQELSPKRWESYRRLKTEAVFADNKSEYLAKKEKKFKNISKINKKIRR"
     gene            3371..4069
                     /locus_tag="ACGI5H_002687"
     CDS             3371..4069
                     /locus_tag="ACGI5H_002687"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898524.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9698385.1"
                     /translation="MKISSQYRSQYSFRYESNINNTRINESMVKKNETVGKDTYLSNI
                     MKQKQELNDRIRDLKYRQEVYTKKINDAIKNLCKSEIRETTNNFSNIEIGIKNSIIEE
                     KNKSTMLDENSTYLNTNDEKESLITKESNEKIEEEILNDEKLEELEQKKDYKEDSNKK
                     EKVSEDLSLVGKTREELENMLKNFINLTQEEIMKLESRIEKLDKNAEEYKQNSKTNIF
                     DKTDEQKKHINVLI"
     gene            4247..5137
                     /locus_tag="ACGI5H_002688"
     CDS             4247..5137
                     /locus_tag="ACGI5H_002688"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861935.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9698386.1"
                     /translation="MKKNILTTMITMIIILMMSMTVMAEPYQEDETSSLKKQSANERN
                     QTNIGTMDGRVQTNAISKGANYDPKYPLKGMLTQLGLNTTGKEGWDLLYGGNPNGVEL
                     RADGKYYYINKGMEGLGFYAAALSGGSYQRIGFGKLDPIEVIADGNWISYKQAQDTLT
                     VIRNFLNSFDWRNASEMERANRAAKLVTEAKYADSKYCNIVYGNLVDKRGVCGSFASS
                     FHLLTRLMGMDSLSILNPSLNHAWNYIQIDGKWYRFDGSEISAFGGSLDFDYRKLKDA
                     TREMTTYYDAKALSILGFNQ"
     gene            complement(5530..6486)
                     /locus_tag="ACGI5H_002689"
     CDS             complement(5530..6486)
                     /locus_tag="ACGI5H_002689"
                     /EC_number="2.7.7.65"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diguanylate cyclase"
                     /protein_id="HFG9698387.1"
                     /translation="MENNTIQKQLRDLSKKIWHIYILNPEEENLKFIISLLDDNLALI
                     GTGKHEFYETLEEFIIGLEKDQTESEQIDFEIIDEWYSCTKVTDEAFIVYGTLWVIEK
                     DYLEKDIYVEMDTRFTMVYRVTDDMIKLIHVHHSIPNFDQMKDEYYPKTITEKAQEAL
                     AMANEFKLKSEKDLMTGLYNRHFFEVHIKEMLKTVSHGYFYIFDLDNFKQVNDIFGHV
                     RGDEILIHFSNILTKVFVNDAIIGRLGGDEFAVFEYSNQSKENVENKAKKVLELCLES
                     NSCSIGISKLENNSDTFQSLYKQSDYALYYSKRNNKGNFSWF"
     gene            7189..8184
                     /locus_tag="ACGI5H_002690"
     CDS             7189..8184
                     /locus_tag="ACGI5H_002690"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729352.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HFG9698388.1"
                     /translation="MSIIELNELTKAYRRFEKKAGFMGSVKSLFNRKYTEKTAILSFD
                     LKIEEGEFVGLIGQNGAGKTTLIKMLTGIIAPSSGEISVMGYYPNKLENNFKKQYAVV
                     MGQKSQLFFELTPADTFLLFKELYDISNEEYKKNLDYFIELFEVSDYLNVQVRTLSLG
                     ERMKMELIVALLHNPKILFLDEPTIGLDAIAQKQIRYFLKEVNETKGTTIILTSHYME
                     DIKSLCSRSIVVENSRKIYDGSTEKLFNHFQKYKKITVSFSNETNIVFPKDCKVVEQT
                     NHKISVIVPKERGNETIKWIFDKYDVKDVMIEEEDIGSIVERIYKKGSDEYYEQL"
     gene            8171..9025
                     /locus_tag="ACGI5H_002691"
     CDS             8171..9025
                     /locus_tag="ACGI5H_002691"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893957.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HFG9698389.1"
                     /translation="MSNYNEASSNDSMFYKFKQSIRRYYEVAKINFKVQLIWRFDVVV
                     NMVFTIVKILFAYILWKAIFGENKIVSGFTFNSMLSYYIISSFLAGIDMSKSTSEEIC
                     NRVKLGTFSKYMIIPINVQNYFIAKNFGMTCFYFVFNMISAFVWIFIFKIDFAFTSNP
                     VQILISILMIFLGFIFMMKLHFFIGILSFKFLEISFFKMIIENIVEFITGTMIPLVLL
                     PETIVTVMKVFPFYYTTYLPSMLLIGRNSNEAIQGLIILALWVLFFSVVNKVMYKRMR
                     TLFDGVGI"
     gene            9025..9816
                     /locus_tag="ACGI5H_002692"
     CDS             9025..9816
                     /locus_tag="ACGI5H_002692"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009906417.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-2 family transporter protein"
                     /protein_id="HFG9698390.1"
                     /translation="MKKNLKIIFMLLKMKLSKMMVFRFDFFGAFFVDSSLFILQLLMF
                     NSIYSHVDSIGGWQQGEMLIFIGTFSLINAINMTIFFFGIYDIPRKIQEGELDYYITK
                     PLDPLFRLTFENINIGSSPLILASILIVLYGISELNSEITLVMIIIYIFMVLLMTLLF
                     YDVCIILRTVSFFVISSSAIMRLEDNLLPMNMKIPGVIYEGVFKVLFYLILPYGIMST
                     IPTQILAGTITINGLIYSILIVFLFTLFMWRFWKLGMRHYKSASS"
     gene            10101..11480
                     /locus_tag="ACGI5H_002693"
     CDS             10101..11480
                     /locus_tag="ACGI5H_002693"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436224.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0042910 - xenobiotic transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0006855 - xenobiotic transmembrane
                     transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MATE family efflux transporter"
                     /protein_id="HFG9698391.1"
                     /translation="MSDVYYSENHEQDNLYEQDNLLAQRFNLFTLLKFAFPTIFMMIF
                     MGLYTIVDTIFVSRFINTNALSAINIVCPIINLIVGIGTMLATGGSAIVARKMGNGDI
                     EGANKAFSLIVLSGVVIGVIITGIGIVFMDYIIIWLGASEVLIKYCRSYLFIILVFAS
                     ANILQVLFQCLFVTAGKPQFGLWLVLGAGCANIILDYVFIVLLQMGISGAALATGVGY
                     LIPTVSGMVFFSKNKGLLKFCIPRLDKRILFEACFNGSSEMVGQLSTAVTTFLFNAMM
                     MKLIGEDGVAAITIIIYSQFLLTSLYIGFSMGVAPIISYNYGSENNTQLNHVFKICIL
                     FISVASLLVFIFSISCSPIIVEIFSQRGSRVYEIARSGFYIFSFSFIFCGYNIFTSSM
                     FTALSNGKVSAILSFLRTFGFITIGLLILPNILNINGIWLAVPSAEILTLFLTIFCIC
                     KYKNRYKYM"
     gene            11928..12641
                     /locus_tag="ACGI5H_002694"
     CDS             11928..12641
                     /locus_tag="ACGI5H_002694"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898517.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000156 - phosphorelay response regulator
                     activity [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HFG9698392.1"
                     /translation="MDTCFNKKILLVDDEKDIVDLIEEVLINDGFKNIIKAYNGLDAI
                     SLCKIACPDVVILDIMLPDIDGIEVCKKIREFSYCSILFLSSKNDDIDKILGLSSGGD
                     DYITKPFSPREIAFRVKAQLRRQQYQSIVPSDSEVIKIGDITIDIEGNRVYKDRNEIE
                     LTGREYHLLSYMAQNVNKIIGKERLYEQVWGVYSSICDNTIMVHIRHIREKIEDNPSN
                     PKILITVKGLGYKLVNRID"
     gene            complement(12913..14451)
                     /locus_tag="ACGI5H_002695"
     CDS             complement(12913..14451)
                     /locus_tag="ACGI5H_002695"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861929.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="HFG9698393.1"
                     /translation="MSLLKVTNLSQCFMDKSLYEKANFDLFKGEHIGVVGQNGTGKST
                     LIKILLGEVVPDSGEIKWQPNINIGHLDQYAEINRDTTISLYLHTAFEELYKIEKEMN
                     LLYQKSAISENEQYLIKASDYQEQLIASNFYSIDNEINKIANGLGLDSIGMNRVVGEL
                     SGGQRAKVILAKLLLSNHDVLLLDEPTNFLDKEHVEWLSNYLNTFNGAFIVVSHDFDF
                     LEKISTGILDIEFGMIKKYHGKYSEFLKQKSHLREDYIRRYQAQQKKIEKEETFIRKN
                     KAGVNSKIARGRQKQLDKIERIAPPSFTGKPNIQFSEIEISAQNALTITNLEVGYYYS
                     LLPKLNFSVDGGQKIVITGFNGIGKSTLLKTLVKDIPRISGDFQFSEQVKIGYYEQDL
                     KWENPDKTPLQIVADKYPKLNTKEIRRHLARCGVKEEHVSRSVSTLSGGEQSKVKLCC
                     MMLSPCNFLILDEPTNHFDAETKDALQNALKQFRGSIILVSHEEKFYKGWIDKVFNIE
                     KQLV"
     gene            15342..15467
                     /locus_tag="ACGI5H_002696"
                     /pseudo
     CDS             15342..15467
                     /locus_tag="ACGI5H_002696"
                     /inference="COORDINATES: protein motif:HMM:NF024804.4"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0043565 - sequence-specific DNA binding
                     [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="AsnC family transcriptional regulator"
     gene            15522..15788
                     /locus_tag="ACGI5H_002697"
     CDS             15522..15788
                     /locus_tag="ACGI5H_002697"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729355.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Lrp/AsnC ligand binding domain-containing
                     protein"
                     /protein_id="HFG9698394.1"
                     /translation="MAFIFINTDLSKSMKEFKKTILEYDTVLECHHISGEYDYLIKVL
                     AEDTSNLEEFISVTLKEIGGIQKANTTIVLSTIKEEFNTIKDIF"
     gene            15837..16421
                     /locus_tag="ACGI5H_002698"
     CDS             15837..16421
                     /locus_tag="ACGI5H_002698"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436217.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DJ-1/PfpI family protein"
                     /protein_id="HFG9698395.1"
                     /translation="MKVLVFLAKGFETMEFSVFVDVMGWARNDYGHDIDVVTCGFKKQ
                     VMSTFNIQVLVDKTIEEVCVDDYDALAIPGGFEEFGFYDEAYDSSFLNLIREFNSKEK
                     IIASICVAALPVGKSGVLKNRKATTYHLKNGKRQRQLSEFDVNVVNEPIVVDKNIITS
                     YCPETAPHVAFKLLEMLTSKEQMDEVKLAMGFKL"
     gene            complement(16426..16749)
                     /locus_tag="ACGI5H_002699"
     CDS             complement(16426..16749)
                     /locus_tag="ACGI5H_002699"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891827.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="winged helix-turn-helix transcriptional
                     regulator"
                     /protein_id="HFG9698396.1"
                     /translation="MKKCLDNYSCPIEATLALIGGKYKTLILWHLKDTILRFNELKKL
                     IPKATPKMLTQQLRELESDGLIIRVVYPVVPPKVEYSLSDFGKSIIPILDSMCDWGSD
                     YLENL"
     gene            16901..17419
                     /locus_tag="ACGI5H_002700"
     CDS             16901..17419
                     /locus_tag="ACGI5H_002700"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429152.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nitroreductase family protein"
                     /protein_id="HFG9698397.1"
                     /translation="MNFVELAKKRYSCRNYQDRKVEKEKLEKVLDVARIAPTGGNRQP
                     QRLIVIQEKEGINKLSKAANIYDAPLAILVCGDKDKVWTRPFDGKQLTDIDTSIVTDH
                     MMLQATELGLASVWVCYFNPDIIREEFSLPDNLEPINILLMGYESKIPESPERHEKTR
                     VPLSEIVSYETL"
     gene            complement(17595..18263)
                     /locus_tag="ACGI5H_002701"
     CDS             complement(17595..18263)
                     /locus_tag="ACGI5H_002701"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891824.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0004826 - phenylalanine-tRNA ligase
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phenylalanine--tRNA ligase beta subunit-related
                     protein"
                     /protein_id="HFG9698398.1"
                     /translation="MLEISHKVKEIYPNIKFGVMVINITHSKPNKENFLVLKNSTIKN
                     IIEQHPEYNRKEKIKTEPVSSYIKYYKKFKKTYPVLLQLESILLKSKGIPDVGVTIES
                     MFLAELKNLLLTAGHDLDKMELPLKIELANGSEHFYGIGGKEHILTKDDLFLSDNIGI
                     LSSILNGPDNRTAITKDTKNIMYFVYGPDKISEKQIQDHLNDIKHYISSAFPDLKVNS
                     IDIF"
     gene            18378..19793
                     /locus_tag="ACGI5H_002702"
     CDS             18378..19793
                     /locus_tag="ACGI5H_002702"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729357.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PLP-dependent aminotransferase family protein"
                     /protein_id="HFG9698399.1"
                     /translation="MWITINRNSNISLSRQIYCEIKDMILDGSLKFEQKLPSSRTLSK
                     ELSVSRNTVLDAYNQLIAEGYLETRNGYGTIVAKGISGHKVDFKLNDTFRDEKDLHTN
                     KQKNYIDFRSGVPELKLFPRKELSKLYKQILYDLSDSDFRYGSTAGVWVLRVEISKYL
                     FRTRGIRCNPKNIMIVSGSTQGLSLISQLLYKSNKKVAVEDPIHKGLLKVISSIGYSV
                     VGIKVDDKGMNTNLIKSIKGISFVYTTPSHQYPLGGILPIQRRLELIKCATENDYYII
                     EDDYDSEFRYEGQPISSLYELSPNKVIYIGSFSKILSPAIRVGFMLLPDNILESYKTL
                     KMYSDVHTETILQHVLAEFIGNGGLEKYIFRMKKLYNRKRKYLIKVLNTEFKNEFKIK
                     GEAAGLHIVAHFYNVKFTESLIHKIFEAGIKVYPIQQYAIENILEYDYEIILGYAHLS
                     FDEIEKGVKILSKIIHMNQGT"
     gene            19992..20474
                     /locus_tag="ACGI5H_002703"
     CDS             19992..20474
                     /locus_tag="ACGI5H_002703"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891821.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_function: GO:0043565 - sequence-specific DNA binding
                     [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HFG9698400.1"
                     /translation="MKTNTDVIMEIIDYIEENLTENLNLDKIAYIANYSKYHLHRMFT
                     NVVGCTIHQYIQRRRLTEAARQLIFTDKYIIDIAITVGYSTHQSFTLAFRNLYKESPQ
                     VYRNKDEFYPIQQRFVLNLNHQIQSEKCISYANMNYKQRRDEINSYLNFNINCEVKVA
                     "
     gene            20471..21055
                     /gene="clpP"
                     /locus_tag="ACGI5H_002704"
     CDS             20471..21055
                     /gene="clpP"
                     /locus_tag="ACGI5H_002704"
                     /EC_number="3.4.21.92"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417022.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009368 - endopeptidase Clp complex
                     [Evidence IEA];
                     GO_function: GO:0004176 - ATP-dependent peptidase activity
                     [Evidence IEA];
                     GO_function: GO:0004252 - serine-type endopeptidase
                     activity [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp endopeptidase proteolytic
                     subunit ClpP"
                     /protein_id="HFG9698401.1"
                     /translation="MSLVPHVIEQTGQGERSYDIYSKLLKDRIIFIGEEINDAIASLV
                     VAQLLFLESEDPDSDIIIYINSPGGSATSGFAIYDTMNYVRCDVSTICIGMAASMSAF
                     LLAGGTHGKRCALPNSEIMIHQPMGGAKGQATDVKIAVDNILKIKERLDKILSENTGK
                     SIEDIRRDTDRDNFMTALEAKEYGLIDYIMNRNE"
     gene            21367..22443
                     /locus_tag="ACGI5H_002705"
     CDS             21367..22443
                     /locus_tag="ACGI5H_002705"
                     /EC_number="2.4.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891817.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HFG9698402.1"
                     /translation="MITISLCMIVKNEEEVIGRCLECVKDIVDEIIIVDTGSTDSTKE
                     IVSKYTDMVYDFEWIDDFSAARNFSFSKASKDYTMWLDADDIILEADREKLLKIKESL
                     DTSIDIVMAKYNVSFDENGNPTLSYYRERLFKRSSNHKWVDPIHEVVPLFGEVFYSDI
                     AISHKKLHRQDPLRNLRIFEKMISEGKTLEPRHQFYYSRELYYNARYKEAIEGFTKFL
                     DSSRGWIEDCISACRDLATCYYLINDEKSALYSLFRSFEFDEPRAEICCDIGKHMFDR
                     QKYKEAIFWYKVALTRDKNDTDGGFKSDDCYGYIPSIQLSVCYDRLGESDKAIYYHEK
                     TKEIKPNDSAVLHNENYFSKFKNS"
     gene            22510..>23143
                     /gene="bclA3"
                     /locus_tag="ACGI5H_002706"
     CDS             22510..>23143
                     /gene="bclA3"
                     /locus_tag="ACGI5H_002706"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861926.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="collagen-like exosporium glycoprotein BclA3"
                     /protein_id="HFG9698403.1"
                     /translation="MLLIMSRNKYFGPFDDNDYNNGYDKYDDCNNGRDDYNSCDCHHC
                     CPPSCVGPTGPMGPRGRTGPTGPTGPTGPGVGATGPTGPTGPTGPTGNTGNTGATGLR
                     GPTGATGATGPTGATGAIGFGVTGPTGPTGATGATGADGVTGPTGPTGATGADGITGP
                     TGATGATGFGVTGPTGPTGATGVGVTGATGLIGPTGATGTPGATGPTGAVG"
BASE COUNT         8552 a         2713 c         3725 g         8153 t
ORIGIN      
        1 aatccttcaa actaaaaaat catttatatt tacagaattt cattttaaga gatgtttatt
       61 ttcacataga taagagaatt taagttctca tatttattat ttgatacaaa tttacatctt
      121 tattatatgt attttaaata aaaaataaaa ttatgaatac tagaaatcta tcttaattag
      181 ctttctaaca taaggctatt taaagtagat aaaactaaaa agggttctct agaaaaccaa
      241 atctatttaa ttatacttac ttactaatac catcacttga tgcaaacaag attctaccac
      301 attttctccg tactctagta taaaatcatc tagttgtgta tctataaaat cacaataatc
      361 atatgaacta ccaatataag cagtcaacat atgtgtacat ctatccattt tatctctaaa
      421 catatatatt attatccccc taaaaaactt tcataaaaac aaaaagaata tctctttttg
      481 gcaactggct gacataactc atagtttatt ttataagcgt tagtccctat agctttgcgt
      541 cactaaattt ctctagtttt gccgatttag ttttattcta caattacaat aatacaatag
      601 aattgcttat tattcaatat acttatttga aaattaaata aatttacaaa tatgaacgtt
      661 attttatatc aaaaaaaata gactatgcat gtagaatata tggaaaaact tgattgtagg
      721 ttttgtatga aaagacagtt gttattaatt taagtgagat aaattgagca acaggcataa
      781 aatgagaaaa caaataatag cagttaattt ttattattaa tactaggtga acattaaatt
      841 tcaaaatacc actagatttt atagaataag aaaatgagac aaacataaat atatgaatat
      901 attaaattat acttgaacat acttatattt tatgataaaa tttcaataat aattattagt
      961 gaaggagtgt cttgcctgat gtcagagtta tatataatgg taaccaacaa ataaatagtt
     1021 ggagacgcat atgggttctg tttaatcaga atttttaagt gtatttttga tacatttgat
     1081 tgttgtgtct tactctgcct ttatagataa ctaacattag acaacaaata ataatattac
     1141 atattacttt gttaaattgt ggtgtagtgg gctttaatct gctacacttt tattaatttt
     1201 acacagtatt attttgaata taattatgtt gaaatagaag atactaaatt ttctagtcca
     1261 caggggtttt ctgtttttgt gtaggtaaat atgtatacca cataaaaagg cagatataaa
     1321 tacctgtgga ctttttttgt agaaaataca cgatacggag gaaataaaaa tgaattataa
     1381 aaatagaaaa cgagcttatt atcaggaaaa ttcctgtatg gataacttta tttgcaaaaa
     1441 ttgtggttgc cttgtagttc ctgaaggagc tggtacacaa catagaaatc attgtccaca
     1501 ttgtttacat agtcttcatg tagatatcat tcctggtgac cgtgctgcag attgtgatgc
     1561 taatatggaa cctattggag tgtgggtgag aaaaaatggt gagtgggcaa ttattcatcg
     1621 ttgtacacgc tgtggacatc ttagttctaa tcgtattgca gctgatgata attcagtgaa
     1681 attaatgtca attgcattaa aaccactggc acagccccct ttcccactag aaagaatcat
     1741 tgaaaagttg gaaaaggagg aaacagaatg aatggtatga aacaaatcaa tttacaagac
     1801 tatggtctaa atagaaattt tattactcaa agtatggaat atcatgattt ataccttgct
     1861 cggattatct cgcaggaaaa gaacttttat caagctgtat gtgtaaatgg tgtactgttt
     1921 gcagaggttt caggaaagct gcgttttgag gctactatac aatctgattt tcccacagtt
     1981 ggtgatttcg ttatgttgga tcgttgcaat aataaaaatg gtaatgctat tattcatcat
     2041 gtgcttcata gaaaaagctt gtttgtgcgt aaggctgctg gaaaggtaaa tgaggagcag
     2101 gtggttgcag ctaatattga cattgttttt ttgtgcatgt cactgaataa ggattttaac
     2161 attcatagat tggagaggta tctgtcttta acatgggaaa gtggagctat cccagtagta
     2221 gtacttacta aatcagactt atgtgacaat gtgcatcgta aattacaagt agttaattct
     2281 atagccttgg gtgtagatgt agttgttacc tcatctatag agccagatgg ttataaacag
     2341 atttctaagt atattaaacc aggctgtact gttgccttac ttggttcttc aggagttgga
     2401 aaatcttcat taattaattg tctgatgggt ggagaatttt taaatacaaa ggaaattcgc
     2461 atagatgatg ataaaggaag acatgccacg actagacgag agctattttt aatttcaggt
     2521 ggtggtattg ttattgacac accaggtatg agagagttgg gaatgtggga tgtttcagaa
     2581 ggtttagata aaagttttgc agatatagaa gcttatttcg gaaaatgtca ttttcgtaat
     2641 tgtactcaca cctcagaacc aggctgtgct atctgggaag ctattgctca tcaagaactt
     2701 tcgcctaaaa gatgggaatc ctatcgtagg cttaaaactg aagcagtatt tgcagacaat
     2761 aaaagcgaat acttagcaaa aaaagaaaag aaatttaaaa atatctcaaa aataaataag
     2821 aagattagaa gataagtgta gtttttttgt tcattctatg agtctatata ctattaatat
     2881 attaaatttg ccatcaattt gttactttaa tgtgattttg atggcaaatt tggtttgtgg
     2941 tattatttaa agcaatttat taattttttt aataaagttt gattttttat atgatgatat
     3001 atacatgtga taatgtatac atatttgtta cgataggctc ctttataaag aggtcttatg
     3061 taagataaga aaaggcatat ttatactaat acataataga gtatatgctt atgtatgata
     3121 gagatgtttc ttaagagcaa aactgcaata ttgctaattt ataaagtaaa aatatatgaa
     3181 ttataaaata caaataatat atttataaaa attattgttt taatttataa taaaaatttt
     3241 ttgttgaaaa taatgctcga acctataaaa ctattaacta atatttgtaa atgtatactt
     3301 ttgatgataa aatataatta agttaagttg gtttttataa acataaattt attttaagga
     3361 ggtgaaataa atgaaaatat ctagtcaata tagaagtcaa tattcattta gatatgaaag
     3421 taatataaat aatacaagaa taaatgaaag tatggttaag aaaaatgaaa ctgtaggaaa
     3481 agacacttat ttatctaata ttatgaaaca aaagcaagaa cttaatgata gaattagaga
     3541 tttaaaatat agacaagagg tttatactaa aaaaataaat gacgcaatta agaacttatg
     3601 taaatcagaa ataagagaaa caactaataa tttttctaat atagaaatag gtattaaaaa
     3661 tagcattata gaagagaaaa ataaaagtac aatgttagat gaaaattcaa cttatctaaa
     3721 tacaaatgat gaaaaagaat ctttaatcac taaagagtct aatgaaaaaa ttgaagaaga
     3781 aatattaaat gatgaaaaat tagaagagtt agaacaaaaa aaggattata aagaggattc
     3841 taataaaaaa gagaaagtat ctgaggactt atctttagta ggtaaaactc gtgaagagct
     3901 tgaaaatatg cttaaaaatt ttataaattt aacacaagaa gaaataatga aacttgagtc
     3961 gagaatagaa aagttagata aaaatgctga agaatacaaa caaaattcaa agactaatat
     4021 atttgataaa acagatgaac aaaaaaaaca tataaatgta ctgatttaaa caatatgttt
     4081 taaaaaaata agtttattat ataatgaaaa tataaaggta caatttcaat acacttctat
     4141 taaaccaata atttatgaac cagacttaat ttcaatttac taataaccat atatttatga
     4201 gttaatagtt ttatgtttta aaaagaatta aataaggggg agtagtatga agaagaatat
     4261 attaactact atgattacca tgattattat attgatgatg agtatgacag taatggcaga
     4321 gccatatcaa gaagatgaaa catctagctt gaaaaaacag agtgcaaatg aacgtaatca
     4381 gactaatata ggcacaatgg atggcagagt gcaaacaaat gcaataagta aaggtgctaa
     4441 ttatgaccct aaatatcctc ttaaaggaat gttaacacaa cttggtctta atacaacagg
     4501 taaagaggga tgggatttac tctatggagg aaatcccaat ggagttgagc ttcgagcaga
     4561 tggtaaatat tattatataa ataagggtat ggaagggcta ggattttatg cggcagcatt
     4621 gtcaggtggc tcatatcaga gaataggctt tggaaaactt gaccctatag aagtaatagc
     4681 tgatggaaat tggatttctt acaaacaagc tcaagataca cttacagtaa tcaggaattt
     4741 tttaaatagc tttgactgga gaaatgcatc tgagatggaa agagctaata gagctgcaaa
     4801 attggtaacc gaagcaaaat atgcagactc taaatattgt aacatagtct atggtaatct
     4861 ggttgataaa cgtggtgtat gtggaagttt tgcaagtagc tttcatttat taacaaggtt
     4921 aatgggaatg gattcactat ctatattaaa tccatcatta aatcatgctt ggaactatat
     4981 acaaattgat gggaaatggt ataggtttga tgggtctgaa atatcagctt ttggtggatc
     5041 attagacttt gattaccgta aattaaagga tgcaacaaga gagatgacta cttactatga
     5101 tgctaaggca ttgtctatat taggatttaa tcaataaaaa tagggggagg cttcttatag
     5161 agcctttttt tattgatttg aaatttaata aggaatttta tatgaaaatt taatcaataa
     5221 aagcaaaaaa ggctctttat aaagcctttc taagtgtttt tttaagtaaa attttttata
     5281 tcaacatcag ttttaatcaa aacatataac attttggact tacttttaaa aataaaatta
     5341 ttaaaatata atattaatca tgtttttagt ttattatatt ctataatagt ggtcatgttg
     5401 actattgtag ttttattaag aatagttggt ttatataaat atatgcaaag atagcttgtt
     5461 gtttacttta cttattagta tataggacaa gatactctaa taaatttgcc tattttaata
     5521 tcttttgtac taaaaccaac taaagtttcc tttattattt cgttttgaat aatacaaagc
     5581 ataatccgat tgtttgtata aagactggaa agtatcagag ttattttcta atttagatat
     5641 acctatagaa caagaattac tctctaggca taattctaaa accttctttg ccttattttc
     5701 aacattctct tttgattgat tactatattc aaaaacagca aattcatctc caccaagtct
     5761 tccaataata gcatcattta cgaatacttt agtcaaaata tttgaaaaat gtattagtat
     5821 ttcatctcct cgaacatgac caaagatatc atttacctgt ttaaaattat ctaaatcaaa
     5881 gatgtaaaag tatccatgtg aaacagtttt aagcatttct tttatgtgta cttcaaaaaa
     5941 atgtctattg tatagtccag tcataaggtc tttttctgat tttagtttaa attcatttgc
     6001 cattgctagt gcttcttgtg ctttttcagt tattgtttta gggtaatact catctttcat
     6061 ttggtcaaag tttggaatag aatggtgaac atggataagt ttaatcatat catctgtaac
     6121 tctgtatacc atagtaaatc gagtatccat ttctacatag atatcttttt ctaggtaatc
     6181 tttttctatt acccaaagag taccatatac tataaaagct tcgtctgtga ctttggtaca
     6241 tgaataccac tcatctataa tctcaaagtc tatttgctct gattctgttt ggtctttttc
     6301 aagacctata ataaattctt ctaatgtttc gtaaaattca tgttttcctg ttccaattaa
     6361 tgcaaggttg tcatctaata aggaaataat aaatttaagg ttttcttctt ctggatttaa
     6421 aatataaata tgccaaattt tttttgataa atctcttaat tgtttttgta ttgtattatt
     6481 ttccatagat taccccctta agatttacag tttatatttt aatgtattat aagttgaact
     6541 cttattacaa tattattata atatagaact aaagaaatta catcctgtat aggtaaaagt
     6601 atatctttta caataaaaat attacagtaa aatgaccagt tttaatatac gtattatatt
     6661 tttaatttat aaacgaatat tataaatgaa atttaaattc aaccttgaag aaataagcta
     6721 aatgtattag tatattaatc catgcttgaa cataaataac ctttatgata tgatatcaat
     6781 aataatatta tgagaggagt gccttgatgt cggagttata taatggtaac caacaattaa
     6841 atagttggag acacatatat tctgtataat cagaaatttc aagtgtattt ttaatacatt
     6901 taatttttgt gtcttattct gcctttatag ataactgaca tatgacaaca aatagtattt
     6961 aaaatatata ttactttgtt aaattatggt gtagtaggct ttaatctgct acacttttat
     7021 taattttgta tagtattatt ttgataacta ttttgaaata gagagcatta atttttctag
     7081 tccacaggag ttttctgttt ttgtgctgtt aaatataagc acagaaaaag gcagatatat
     7141 acctgtggac tttttttata taaattatga aatatggagg tagttaaaat gagtataatt
     7201 gaacttaatg aactgactaa agcttataga agatttgaga aaaaggcagg atttatgggg
     7261 agtgtaaagt ctttatttaa taggaaatat acagaaaaaa cagctatatt gtcatttgat
     7321 ttaaagatag aagaaggaga atttgttgga ttaataggtc aaaatggagc tggtaaaact
     7381 actcttatta agatgttaac tggtattatt gcaccgtctt ctggagaaat atctgtaatg
     7441 ggttattacc ctaacaaatt agaaaataat tttaaaaaac aatatgctgt tgttatgggc
     7501 caaaaaagtc aactattctt tgaattgaca ccagcagata cgtttctttt atttaaagaa
     7561 ttatatgata tatctaatga agaatataaa aaaaacttgg attactttat cgaattattt
     7621 gaggtatctg actatttaaa tgttcaagtt aggacgcttt ctttaggaga aagaatgaaa
     7681 atggaactaa tagtagccct tctacataat ccaaaaatat tatttttgga tgaaccaact
     7741 ataggcttag atgctatagc ccaaaaacaa attaggtatt tcctaaaaga agtaaatgaa
     7801 acaaaaggaa ctactattat acttacttct cattacatgg aagatattaa gagtctctgt
     7861 agtagaagta ttgttgtaga aaatagccgt aaaatatatg atggttctac agagaaacta
     7921 tttaatcatt ttcaaaaata taaaaaaata acagttagtt tttccaatga aactaacatt
     7981 gtatttccaa aagattgtaa agttgttgaa caaacaaatc ataagatatc agtaattgtg
     8041 ccaaaagaaa gaggaaatga aacgattaaa tggatttttg ataaatatga tgttaaagat
     8101 gtaatgattg aagaagaaga tataggtagt attgtagaga gaatatataa gaaaggaagt
     8161 gatgagtatt atgagcaact ataatgaagc aagttcaaat gattcaatgt tttataaatt
     8221 taaacagagt attagaaggt attatgaagt agccaaaatt aactttaaag tgcaacttat
     8281 ctggagattt gatgtggtgg ttaatatggt gtttacgatt gtaaaaattt tatttgctta
     8341 tattttatgg aaagcaattt ttggtgaaaa taaaatagtc tctggtttta catttaactc
     8401 tatgttgtct tactatataa taagctcatt tttagcaggt attgatatgt caaagagtac
     8461 cagtgaagag atatgtaatc gtgtaaaatt gggcaccttt tcaaagtaca tgattattcc
     8521 aattaatgtt caaaattatt ttattgctaa aaattttgga atgacatgtt tttattttgt
     8581 atttaatatg atttctgcat ttgtatggat ttttatattt aaaatagatt ttgcctttac
     8641 atcaaatcca gttcaaatat taatttcaat tttgatgatt tttctagggt ttatttttat
     8701 gatgaaactc cacttcttta ttgggatttt gtcatttaaa tttcttgaga ttagtttttt
     8761 taaaatgata attgaaaata ttgttgaatt tattacagga acaatgatac cacttgtact
     8821 cttaccagaa actatagtaa cagttatgaa ggtatttcca ttttattata caacatattt
     8881 gccatctatg ttactaatag gtagaaacag caatgaggca atacaaggat taattattct
     8941 agcattatgg gttttatttt tttctgtagt aaataaagtt atgtataaaa gaatgagaac
     9001 attatttgat ggggtgggta tatgatgaaa aaaaatttga aaataatatt tatgttatta
     9061 aaaatgaaat tatcaaagat gatggtattt agattcgatt tttttggagc attttttgta
     9121 gatagttcat tatttatatt acaacttcta atgtttaata gtatatattc tcatgtagac
     9181 tcaatagggg gatggcaaca aggagagatg ttaatattta taggaacttt ctcattaata
     9241 aatgcgataa atatgacgat tttctttttt ggtatttatg atattccacg aaaaatccaa
     9301 gaaggagaat tagactacta tattacaaaa ccattagacc cactatttag gttaacattt
     9361 gaaaatatta atattggttc atcaccatta attctagcaa gtatacttat tgttttatat
     9421 ggaatatctg agttaaactc agagataact ttagttatga taataatata tattttcatg
     9481 gtgttattga tgacattact tttttatgat gtatgtatca tacttagaac agtttcattt
     9541 tttgttatat catcttctgc gataatgaga ttagaagata atttattgcc aatgaatatg
     9601 aaaattcctg gtgtaatata tgaaggtgtt tttaaagtat tattctattt aatcttacca
     9661 tatggaatta tgtcgacaat tccgactcaa attttggctg ggacaataac aattaatgga
     9721 ttaatatact caattttaat tgtatttttg tttacattgt ttatgtggag attttggaag
     9781 ttaggtatga gacattataa aagtgcaagt agttaataaa ttagtaaaaa tagacaatgt
     9841 ataactatat ataaatacgt ttcatatgac actaaactat gtgaacaagt atttgcgcta
     9901 aaggcactga aagctataaa attattaaag taaggattta aaagtttctt tagtagaaat
     9961 ataattgtgt aaaaaagcaa gattaattaa aactatatcc aaataattag atataattct
    10021 tatgcagaaa ggaggtctgt aaatgtctaa ttgtttggaa tatattttaa aaataattaa
    10081 tgtacagaaa aataaacaaa atgagtgatg tatattattc agaaaatcat gaacaagata
    10141 atctttatga gcaagataat ttactggcac aaagatttaa tttatttact ctattgaagt
    10201 ttgcatttcc tactattttt atgatgattt ttatggggtt gtatacaatc gtagatacta
    10261 tatttgtatc aagatttatt aatacaaatg ctctatcagc aattaatatt gtatgtccaa
    10321 ttattaatct tatagttgga attggaacta tgcttgccac tggaggaagt gctattgtag
    10381 cacgtaagat gggaaatggt gatattgagg gagcaaataa agctttttct ttaatcgtat
    10441 tatcaggagt tgtaattggg gtaataatta ctggtatagg tattgtattt atggattata
    10501 tcattatatg gttaggagca agtgaagttt taattaaata ttgtcgttca tatcttttta
    10561 ttatcttggt ttttgcttct gcaaatatac tacaagtatt atttcaatgt ttatttgtaa
    10621 cagctggaaa gcctcaattt ggattatggc tagtgttagg tgctgggtgt gctaatataa
    10681 ttcttgacta tgtgttcatt gttctgttac aaatgggtat tagtggagca gcacttgcaa
    10741 ctggagtagg atacctaatt cctaccgttt caggtatggt tttcttttca aaaaataaag
    10801 ggttacttaa attttgtata cctagactag ataaaagaat attatttgaa gcttgtttta
    10861 atggttcatc tgaaatggtg ggtcaactat caacagcagt tactactttt ttatttaatg
    10921 ctatgatgat gaaattaatt ggtgaagatg gggttgcagc tattacaata attatttatt
    10981 ctcaatttct tttaacttcg ctttatatag gtttctcaat gggtgttgca ccaataataa
    11041 gttataacta tggaagtgaa aataatacgc agttaaatca tgtttttaag atttgtatat
    11101 tatttatttc agtagcatct ttattggtat ttatcttttc tatatcatgt tcaccaatca
    11161 ttgtagagat tttttctcaa agaggaagcc gagtttatga aattgcaagg tctggatttt
    11221 atatattttc ttttagtttt attttttgtg ggtataatat ttttacttcg tctatgttta
    11281 cagcattatc aaatggaaag gtgtctgcaa tattatcttt tctacgtaca tttggattta
    11341 taactatagg tttattgata ttgccaaata tattaaatat aaatgggata tggttagcag
    11401 taccaagtgc tgagatttta actttatttt taaccatttt ttgtatatgt aagtataaga
    11461 atagatataa atatatgtag atattaaata aatagtttag gtagatattt tatgttttaa
    11521 taagtaattc aattagtggg agatatatac tattgaaaat taaagttata attgatataa
    11581 agaattaata aaaataacat ataaaagttt aaaagggagt tgaacttaaa gtttgattag
    11641 aaaaagtcaa ttttaagaca actcctttta ttttactatt gtattaatct gtatctgtaa
    11701 gtgtattagt ctaatattat aaactttgga tgaaattaat tttctatagg ttttaatgta
    11761 tcatacactt tattttaaag aaacttatct taattttcat agtgattgaa tttgtctatt
    11821 agagatgtta ctattagtaa tgtaaaagca agagtagtga atataaaaaa caagatagtg
    11881 atactgcaag attagaatat aataaatttt tatggagaga tttcaatatg gatacatgtt
    11941 ttaataaaaa aatattactt gttgatgatg aaaaggatat agtagattta attgaagaag
    12001 tactcataaa tgatggtttt aaaaacatta ttaaagctta taatggtcta gatgctattt
    12061 cgctgtgtaa gatagcatgt ccagatgttg tcattcttga tataatgtta ccagatatag
    12121 atggtataga agtgtgtaaa aaaattcgag agttttcata ctgttctatt ctttttttat
    12181 catcaaaaaa tgatgatatt gacaaaatac taggtcttag tagtggggga gatgactata
    12241 taacaaagcc attcagtcca agagaaattg cttttcgagt taaagcgcaa ttacgtagac
    12301 aacagtatca aagcattgta ccatcagata gtgaagttat taaaatagga gatattacta
    12361 ttgatataga aggaaaccgt gtatataaag atagaaatga gattgagtta actggaaggg
    12421 agtatcatct tttaagctac atggctcaaa atgtaaataa aattatagga aaagaaagac
    12481 tctatgaaca agtatgggga gtatatagta gtatttgtga caatacaatt atggtgcata
    12541 tacgacatat aagagaaaaa attgaagata acccctcaaa tcctaaaata cttataacag
    12601 ttaaaggact aggatataaa cttgtgaata gaatcgatta gaatagattt taatattaat
    12661 gaagatatct caagttgaat ttttagttaa tgaggcattc ttttatgggt aaaatcaaat
    12721 atattttcgt tatctcaaca atgaagaaga ggtctatctc tattttgaga tagcctcatt
    12781 aagtttatat cctggtaatg tactttatct tctaataaaa tttttttagt ttatttgcag
    12841 tgaaacatta actagaacat taaaatttgc attgaaatac taattaaata atattgtata
    12901 ttgtgtataa acttatacta attgtttttc tatattaaat actttatcaa tccaaccttt
    12961 ataaaatttt tcttcatggg aaactaggat tatacttcct ctaaactgtt tcaaagcatt
    13021 ttgtaaagca tcctttgtct ctgcatcaaa gtgattggtt ggttcatcca ggataagaaa
    13081 attacaagga gataacatca tacaacataa tttaacctta gattgttcac caccacttaa
    13141 agtagataca ctccttgaaa catgctcttc cttcacacca catctggcta gatgacgtct
    13201 aatctctttt gtatttaatt ttggatattt atctgctact atttgaagtg gggttttatc
    13261 aggattttcc cattttaaat cttgctcata ataaccaatt ttaacttgtt ctgaaaactg
    13321 gaaatctcca gatatacgag gaatatcttt gactaatgtc tttaacaagg tagatttacc
    13381 gattccatta aaaccagtta taactatttt ttgacctcca tcaacagaga aatttaattt
    13441 tggaagtaaa gaatagtagt atccaacttc aagatttgtt atagtaagag cattttgagc
    13501 cgatatttca atttctgaaa attgaatatt tggttttcct gtaaaactag gaggagctat
    13561 tctttctatt ttatccaatt gtttttgtct tcctcttgca atttttgaat ttactccagc
    13621 tttattttta cgtataaatg tttcttcttt ttctattttc ttttgttgtg cttgatacct
    13681 tctaatataa tcttctctta aatgtgattt ttgtttaagg aactctgaat attttccatg
    13741 atatttctta atcatgccaa attctatatc aagaatacct gtagaaattt tttctaaaaa
    13801 gtcaaaatcg tgggaaacta caataaatgc cccattaaat gtatttaaat aatttgagag
    13861 ccattcaaca tgttctttat ctaaaaagtt tgttggttca tctaataata gaacatcatg
    13921 gttagaaagt agtaattttg ctaaaattac ctttgccctt tgaccaccac taagctctcc
    13981 aacaacacga ttcattccta ttgaatctaa tccaagacca tttgctattt tatttatttc
    14041 attatctata gaatagaaat tacttgctat tagttgttcc tgataatctg atgctttgat
    14101 tagatattgc tcattttcag atatagcact tttttgatag agtaaattca tttccttttc
    14161 tattttataa agttcttcaa atgcagtgtg taaatagagt gatattgttg tatctctatt
    14221 gatttctgca tattggtcta aatggcctat attgatatta ggttgccact tgatttctcc
    14281 tgaatctgga acaacttctc ccaataaaat tttaattaat gtacttttac ctgtaccatt
    14341 ttggccaact acacctatat gttcaccttt gaataaatca aagttagctt tctcatacag
    14401 tgatttatcc ataaaacatt gtgataaatt agttactttt aataaactca taattcaaac
    14461 tccttttctt ttattaaaaa atttatggaa ataaaaaaag cagaggaatg gcattgtaaa
    14521 atgccgacct ctgcttttgg aaaaacaaaa ggtcatagac aagcattgtt gtctatgacc
    14581 agaaaatcta tattatctat cggcaaatag gtaattttaa ataagcatag ccaaaaaact
    14641 atactaaacc tatatttgcc gatgaagata gaaagcttta agctttcaga ttaacctcta
    14701 cacaacgctt catcgtatac atttgtgtag agttaagttt tctaacaagt ttaactaatt
    14761 ctatataaat cataattatt cacatcctaa tcttagtatt aattctagtt tatctgtatt
    14821 taaattgtac ttttgtactt tgtggattat cttatttatt taaaatatgt tttattaatt
    14881 atagcttaag ttatgttatc ataatactta gttatagtca ataagaaagt tatatttact
    14941 attattatat taatttagta aatctatcat tacaaagtta tttgaagact cgctatcaat
    15001 aaaattttat agtctataag aaaattaaga ttatgagttt tataattttg atatagggat
    15061 actattttca taaatattac aacatgtaga agtatatgtc tattattgtt gaattttcaa
    15121 tgatatatta aggttctaat atattataca aaataaaaac attaattcaa cttaaataat
    15181 tttaagtatt atatgtgttt tgattaaaga aaactaaaat tttaaggaaa aataacatat
    15241 ttgtattaaa ttttattgaa atgattaaat ttatttactt aatgtaaatt attagctaaa
    15301 attgtattaa ataattaagg aggtgagtag ctctggatga aatagattta aaaataatta
    15361 attctctaaa aaagaatagt agggcttcaa cctctgaaat aagcagacaa attaatttat
    15421 cagtaccagc agtctcagag cgtataagga aaattgagca gtcaaattta attcaaaagt
    15481 acactattca aattaatcgg gaaaaaacaa aatataagct tttggctttt atatttatca
    15541 atactgattt atctaaaagt atgaaagaat ttaagaaaac tatattggaa tatgatactg
    15601 tattagaatg tcatcatatt tcaggagagt atgattactt aataaaagta ttagcagaag
    15661 atacaagtaa tcttgaagag tttatatcag tgactttgaa ggaaattggg gggattcaaa
    15721 aagctaatac aaccattgtt ttatctacaa ttaaagaaga atttaataca ataaaagata
    15781 ttttttaaat aatttactag taaagtgtta attatatttt aggaggaaaa tagaatatga
    15841 aagttttagt ttttttagca aaaggttttg aaactatgga atttagtgta tttgtagatg
    15901 ttatgggatg ggctcgtaac gattatgggc atgatattga tgtagtgact tgtggattta
    15961 aaaaacaagt tatgagcaca tttaatatac aagtattagt tgataagacg atagaagaag
    16021 tatgtgttga tgattatgat gctctagcta ttcctggggg atttgaagaa tttggatttt
    16081 atgatgaagc atatgattca tcttttttaa atctaataag ggagtttaat tcaaaagaaa
    16141 aaataatcgc ttctatttgt gtggcagcat tgccagttgg aaaaagtggt gttttaaaaa
    16201 atcgtaaagc tactacatat catttgaaaa atggtaaaag acaaagacag ttaagtgagt
    16261 ttgatgtaaa tgtagttaat gaaccaattg ttgtagataa aaatattata acctcatatt
    16321 gtccagaaac agctccacat gtagctttta agcttttaga aatgttgaca tctaaagaac
    16381 aaatggatga agttaaatta gcaatgggat ttaaactgta atggtttata gattttctaa
    16441 gtaatcagaa ccccagtcac acatggaatc taaaattgga ataatactct ttccaaaatc
    16501 agatagcgag tattctactt ttggaggaac aacaggataa accactctta taattaaacc
    16561 atctgattct aattcacgta attgttgagt taacatctta ggcgttgctt taggaattaa
    16621 tttttttaat tcattgaacc tcaatatagt gtctttaaga tgccaaagta taagtgtctt
    16681 atatttacca ccaatcaatg caagtgttgc ttctattggg caactgtaat tatctaaaca
    16741 ttttttcatt tttgggctcc tttatttatt ttaaagtatc tttttaggta ctatattaca
    16801 aaaaagtgca ttattgtaat atagtaccat agtgataaaa ttatagcata ggttaaataa
    16861 atcatcaact tagcctaata aaacaatagg aggtaaataa atgaatttcg ttgaacttgc
    16921 aaaaaaaaga tattcttgcc gtaattatca agatagaaag gttgaaaaag aaaaacttga
    16981 gaaggtttta gatgttgcaa gaatagctcc aactggtggt aatcgtcaac ctcaaagatt
    17041 gattgttatt caggaaaaag aaggtataaa taaactttct aaggctgcca atatatatga
    17101 tgctccatta gcaattcttg tatgtggaga taaagacaaa gtttggacaa gaccttttga
    17161 tgggaaacaa cttacagata ttgacacaag tatagttaca gaccatatga tgttacaggc
    17221 aactgaactt ggattggcaa gtgtttgggt gtgctatttt aatccagata taattagaga
    17281 agagtttagt ttgccagata atctagaacc aataaatata ttattgatgg gatatgaatc
    17341 taagatacca gagagcccag agagacatga aaaaactcgt gttcctttaa gtgaaattgt
    17401 ttcttatgaa actctttaat tataaaatta agttattcat aggataaatg taataaagtg
    17461 tttattataa acaaaattca aaataaataa tatctacata taattaattt tagtgaagta
    17521 tatctagttt aactagaatg tatacttcac taatttattt attcaaaata tttatgagga
    17581 ttttaatata ttaactaaaa tatatcaatt gaattaactt ttaaatctgg aaaagcactt
    17641 gaaatatagt gttttatgtc atttaaatgg tcttgaattt gcttttctga tattttatca
    17701 ggtccatata caaaatacat aatattttta gtatcttttg ttatagctgt tcgattatca
    17761 gggccattaa gaatactaga taatatacca atattatctg ataaaaataa atcatctttt
    17821 gttaaaatat gttctttacc acctatacca taaaaatgtt cacttccatt tgctaattct
    17881 attttcaaag gtaattccat tttatcaagg tcatgacctg ctgttagaag aagatttttc
    17941 aattctgcta aaaacattga ctcaattgtt acacctacat ctgggatacc ttttgatttt
    18001 aatagaatag attctaattg aagcaataca gggtaagttt tcttgaattt tttataatac
    18061 tttatataac ttgaaacagg ctctgtttta attttttctt tacgattgta ttctgggtgt
    18121 tgttctataa tatttttaat tgtagagttt ttaagaacta aaaaattttc tttattaggt
    18181 tttgaatgtg taatatttat aaccataact ccaaatttaa tattgggata aatttcttta
    18241 actttatgtg atatttctaa cataatatag actccttttt attttatatt ttatgatata
    18301 atcttagcaa attaaaagtg gattttgtag ttccattttt atagtaattt tatagaacca
    18361 cttttggagg tattagaatg tggattacga ttaatagaaa tagtaatata tcattatcaa
    18421 gacaaattta ttgtgagata aaagatatga ttctggatgg aagcttaaag tttgagcaaa
    18481 aactgccatc atctaggact ttatcaaaag aactatctgt atctcgtaat acagttttag
    18541 atgcatataa tcaattaatt gcagaaggat atttggaaac aaggaatgga tatggaacaa
    18601 ttgtagctaa aggaatatca gggcataaag ttgattttaa gttaaatgat acttttagag
    18661 atgaaaaaga tttacatact aataaacaaa aaaattatat agattttcgt tcaggagttc
    18721 cagaattaaa actatttcca cgcaaagaac tttcaaagct atataaacaa atactgtatg
    18781 atttatcaga ttcggatttc agatatggaa gtacagctgg tgtatgggtt ttaagagtgg
    18841 aaatatctaa gtatttattt cgtactagag gaattagatg taatcccaaa aacattatga
    18901 ttgtttctgg ttcaacacaa ggtttatctt taatttcaca gcttttatac aaaagtaata
    18961 aaaaggttgc tgtagaagac cctattcata aaggcttatt aaaggttatt tcatctattg
    19021 gatattcagt tgttggaatt aaagtagatg ataagggaat gaataccaac ttaataaaat
    19081 caataaaggg gatttctttt gtttatacta caccttctca tcaataccca ttaggaggga
    19141 ttttacctat tcaaagaaga ctagagctta ttaaatgtgc aacagagaat gattactata
    19201 taattgaaga tgattatgat agtgaattta gatatgaggg tcaaccaatt agttctcttt
    19261 atgaacttag tccaaataaa gtaatttaca taggttcttt tagtaaaata ttatctccag
    19321 ctattcgtgt tggatttatg ttattaccag acaatatttt agaaagctat aaaaccttaa
    19381 aaatgtactc tgatgttcat acagaaacaa tattgcaaca tgtattagct gaatttattg
    19441 gaaatggagg tttagagaag tacatattta gaatgaagaa gttgtacaat agaaaacgta
    19501 agtacctcat aaaagtttta aacacggaat ttaaaaatga atttaaaata aaaggtgaag
    19561 cagcagggct tcatatagtt gctcatttct ataatgttaa atttacggaa agtttaattc
    19621 ataaaatttt tgaagcaggt ataaaagttt atcctataca acaatatgca attgagaata
    19681 tattagaata tgactatgaa attatactag gttatgctca tcttagtttt gatgaaattg
    19741 aaaaaggtgt aaaaatactc agcaaaataa tacatatgaa tcaaggtaca tagataaaac
    19801 atgtagcaat ctacatataa tagatgtaat taagtttaaa ctttaaaaga aatatatatt
    19861 aatatttttg tataaaaata cctgatattt ttttatcgat actttattgc tatacactaa
    19921 attaagatag caatttatat taagaaaaaa ctttttgcat aggttataat acttaaaagg
    19981 agaggataga gttgaaaaca aatacagatg ttattatgga gataattgat tatatagaag
    20041 aaaatcttac agaaaatcta aatttagata aaatagctta tattgctaat tattcaaaat
    20101 accatttaca cagaatgttt acaaatgttg taggatgtac tatccatcaa tacatacaga
    20161 ggaggagact tactgaagca gctagacaac ttatatttac agacaaatat attatagaca
    20221 tagctattac agtaggatat tctacacatc aatcttttac actagcattt agaaatttat
    20281 ataaagaatc tccacaagta tatagaaata aagatgaatt ttatcctatt caacagagat
    20341 ttgttttaaa tctaaatcat caaattcaaa gtgaaaaatg tatttcttat gcaaatatga
    20401 attataaaca aagaagagat gaaatcaatt cttatctgaa ctttaatatt aattgtgagg
    20461 tgaaagtagc atgagtttag tgccacatgt aattgaacaa acaggtcaag gggaaaggtc
    20521 ttatgatata tattcaaaat tattaaaaga tagaattata tttataggag aagaaattaa
    20581 tgatgctatt gcaagtttag tagtagctca attactgttt ttagaatcag aagacccaga
    20641 ttcagatata attatatata taaatagccc tggtggctct gctacatcag gatttgctat
    20701 atatgatact atgaattatg tcagatgtga tgtatcgact atttgtattg gtatggctgc
    20761 aagcatgagt gcttttttac ttgcaggagg aacacatgga aaaagatgtg ctttacccaa
    20821 ttcagagatt atgattcatc agccaatggg aggagctaaa ggtcaagcaa cagatgtaaa
    20881 aatagctgta gataatatat tgaaaataaa agaacgatta gataaaattc tttctgaaaa
    20941 tacaggtaaa tcaatagaag atattaggag agatacagat agagataatt ttatgactgc
    21001 actagaggct aaagagtacg ggctgattga ttatataatg aataggaatg aataaagtat
    21061 caaagtatca tattaaaatg tctgttttac aaatatatat ataatattaa ataagagtgt
    21121 ctcaaaatga actttttagt ttatgggaca ctcttttttg tatgaaatta aatatggttt
    21181 tatcatttcg acaattatta ccaaatttca agtttaataa attctactat aaaaaataca
    21241 taaaagataa ggttctttag taactttctg tcgtcaaaag tttttataaa tttaataaca
    21301 aaacaagaga aaataccata tattacttat gtctgcaata tatagaagac aaaggagttg
    21361 tacattatga ttacaataag tttgtgcatg attgttaaga atgaggaaga agttataggc
    21421 agatgcttag aatgtgtaaa ggatatagta gacgaaatta taattgtaga taccggttct
    21481 acagattcca caaaagaaat agtctcaaaa tatacagaca tggtgtacga tttcgaatgg
    21541 atagatgatt tctctgctgc aagaaatttt tcattttcta aagcttctaa agactatact
    21601 atgtggcttg atgcagatga cataatttta gaagctgata gagaaaaatt attaaagatt
    21661 aaagaaagct tggatacttc cattgatatt gttatggcaa aatacaatgt atcctttgat
    21721 gaaaatggta acccaactct ctcatattat agagaacgat tgtttaaaag aagttctaat
    21781 cataaatggg ttgaccctat tcatgaagta gtacctcttt ttggagaggt attttattct
    21841 gacattgcaa tatctcataa aaagcttcat agacaggacc ctctaagaaa tcttagaatt
    21901 tttgaaaaaa tgatttcaga aggaaaaaca ttggagccaa gacaccaatt ctattattct
    21961 agagagttgt actataatgc taggtataaa gaagcaatag aaggttttac taagttttta
    22021 gactcatcaa gaggatggat tgaggattgt atcagtgctt gcagagattt agccacatgt
    22081 tattacttaa ttaatgatga aaaaagtgcc ttatattcat tgtttagaag tttcgaattt
    22141 gatgagccaa gagcagaaat ttgttgtgac ataggaaagc atatgtttga tagacaaaaa
    22201 tataaagaag ccattttttg gtataaggta gcattaacaa gagataagaa tgatactgat
    22261 ggaggcttta agtcagatga ttgttatgga tatataccat ctatacaatt aagtgtctgt
    22321 tatgacaggt taggagaatc agataaagct atttattatc atgaaaaaac aaaagaaatc
    22381 aaacctaatg atagtgctgt tttgcacaat gaaaattatt ttagtaaatt taaaaatagt
    22441 tgatgggtca caatcatact aaatttgaca tattatatat agagcttaaa agctcaaata
    22501 tatcaggagg tgcttttaat aatgagtaga aataaatatt ttggaccatt tgatgataat
    22561 gattacaaca atggctatga taaatatgat gattgtaaca atggtcgtga tgattataat
    22621 agctgtgatt gccatcattg ctgtccacca tcatgtgtag gtccaacagg cccaatgggt
    22681 ccaagaggta gaaccggccc aacaggtcca acgggtccaa caggtccagg tgtaggggca
    22741 acaggcccaa caggaccaac cggtccgact ggtccaacag gaaatacagg gaatacagga
    22801 gcaacaggat taagaggtcc aacaggagca acaggggcaa caggcccaac aggagcgaca
    22861 ggagctatag gatttggagt aacaggtcca acaggcccaa caggagcgac aggagcaaca
    22921 ggagcagatg gagtaacagg tccaacaggt ccaacgggag caacaggagc agatggaata
    22981 acaggtccaa caggagcaac aggggcaaca ggatttggag taacaggtcc aacaggccca
    23041 acaggagcaa caggagtagg agtaacagga gcaacaggat taataggtcc aacaggagca
    23101 acaggaacac ctggagcgac aggcccaaca ggagcagtag gag
//
LOCUS       DAYAOO010000065        22953 bp    DNA     linear   BCT 12-OCT-2024
DEFINITION  TPA_asm: Clostridioides difficile isolate ST8-SSI-h139-18
            SAMN40601845-rid21577343.denovo.065, whole genome shotgun sequence.
ACCESSION   DAYAOO010000065 DAYAOO010000000
VERSION     DAYAOO010000065.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN40601845
            Sequence Read Archive: SRR28438827
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 22953)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 22953)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-MAY-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-MAY-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002157583.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002157583.1
            Genome Coverage       :: 163x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/11/2024 16:19:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 4,038
            CDSs (total)                      :: 3,963
            Genes (coding)                    :: 3,930
            CDSs (with protein)               :: 3,930
            Genes (RNA)                       :: 75
            rRNAs                             :: 6, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 60
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 33
            CDSs (without protein)            :: 33
            Pseudo Genes (ambiguous residues) :: 0 of 33
            Pseudo Genes (frameshifted)       :: 7 of 33
            Pseudo Genes (incomplete)         :: 25 of 33
            Pseudo Genes (internal stop)      :: 11 of 33
            Pseudo Genes (multiple problems)  :: 8 of 33
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..22953
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN40601845-rid21577343.denovo.065"
                     /isolate="ST8-SSI-h139-18"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Denmark"
                     /collection_date="2018"
                     /collected_by="Statens Serum Institute"
     gene            <1..321
                     /locus_tag="ACGI5H_002707"
     CDS             <1..321
                     /locus_tag="ACGI5H_002707"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893427.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="M20/M25/M40 family metallo-hydrolase"
                     /protein_id="HFG9698404.1"
                     /translation="VEKADCYTGNTIESERFFPGWLYDEEDEFVQAAYKGLKEAGIDS
                     EITQYSFCTNGSHYAGEAGIRTIGFGPSKENLAHTIDEYIELDQLFKGAEGYYGILKS
                     VYKK"
     gene            337..1920
                     /locus_tag="ACGI5H_002708"
     CDS             337..1920
                     /locus_tag="ACGI5H_002708"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421978.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidohydrolase family protein"
                     /protein_id="HFG9698405.1"
                     /translation="MRILIKHGLIVDGNKTPAYEGDILIENEKILKISQDLNEEADKV
                     IDAKGRVICPGFIDTHSHSDLVILVNPYNEVKIRQGITTEVLGQDGISMAPLPQEHIS
                     SWRKNLAGLDGESDEIDWKYETTENYLKMMDYNGVGLNETYLVPHGNVRMEAMGLEDR
                     PATKEEIQKMCEITERELKAGAIGLSTGLIYIPCAYSLTEEIIEMCKVVAKYDGVFVV
                     HQRSEADTILTSMEEIIEIGKQSGVKVHFSHFKVCGKANWKYIPQVIELLEKAEKEGI
                     RVSFDQYPYAAGSTMLGVVLPPWAHSGGTDKLIERLSDENERAKMKKDIANGIEGWDN
                     FIEFAGIDQIFVTSVKTEKNKDTIGKNLLEIGKMRGKDPLDATFDLLKEEENAVGMVD
                     FYGLEEHIIGFMKRDEQNVCTDGLLAGKPHPRAYGSFPKILGRYVRELNVLTIEEAVY
                     KMTKKAATSFSIKDRGELKEGYFADIVIFDKDTVSGCDDFINSMQYPTGIDYVIINGN
                     CVVEEGKYNKIKAGKVLKN"
     gene            1948..3276
                     /gene="ssnA"
                     /locus_tag="ACGI5H_002709"
     CDS             1948..3276
                     /gene="ssnA"
                     /locus_tag="ACGI5H_002709"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898311.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016810 - hydrolase activity, acting on
                     carbon-nitrogen (but not peptide) bonds [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="putative aminohydrolase SsnA"
                     /protein_id="HFG9698406.1"
                     /translation="MILVGNGRLISQDSLNPYMEDGCVVINDNLIEDIGTTEEMKAKY
                     PVHEFIDAGKKIIMPGLINSHMHIYSSFARGMAVPGKPSENFLEILNNLWWRLDKQLT
                     LEDTKYSAYATYIECIKNGVTTVYDHHASPNAIEGSLFTISDVAKDLGIRTCLCYEVS
                     DRDGGNTIQQGINENVNFIKYAQKDDTDMIKGMFGLHAAFTLSDDTLNKCASEMAGLD
                     TGYHVHVAEGLADLQYNVDKYGKRVLERFNDFGVLKEKTIAVHCIYISAEEISLLNKT
                     NTFVVHNPESNMGNAVGCSPAIELLKRGVTVGLGTDGYTSDMFESLKVANIIHKHHLK
                     DPRVGFEESQTMLFDNNRKIAKAYYKNDLGVLKKGAYADVIVVDYIPHTPLTENTIGG
                     HTIFGMSGRSVDTTIINGKVLMKDRKLINIDEESILAKSRELSQNLWNRI"
     gene            3475..4827
                     /locus_tag="ACGI5H_002710"
     CDS             3475..4827
                     /locus_tag="ACGI5H_002710"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0015205 - nucleobase transmembrane
                     transporter activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="nucleobase:cation symporter-2 family protein"
                     /protein_id="HFG9698407.1"
                     /translation="MSRDKSPKIAPVDERLPVSKSWVFSLQHVLAMCAGAVAVPMMIG
                     SAARLDHASIVFLINACLFMAGIGTLIQSVGIGNIVGAKIPVIEGTSFAAVAGMTAIA
                     SSYSDSQVAIQTVFGSVIVAGLFCILLAPVFEKLIRFFPSVVTGTVVMVIGISLFPVG
                     IKWITDNKLEAVEPNSLALALAVLAITLLSFKFLKGIWNSTAILVGIVLGTLLSMAVG
                     MADFSAVNGVGWLNLNVPLKFGMPRFEPSAILSLCLIMLVLMTESVGNMIAIHEMVDK
                     EVTGKNIKRGLFGDGISTALSGIFNSFPITPFGQNTGIVGLTGIKSRFIAVYAGVILL
                     VLGFLPKFAAIIGAIPKPVLGGVGFAMFGMVMVGGVKTLSKVKFDGTKNGVIVAVSVG
                     LSMIPLTNPDFYHNFPTWVQTIFHSGITTGSLSAVLLNIFFNELGSKKEKNNKVEEAK
                     "
     gene            5019..6128
                     /locus_tag="ACGI5H_002711"
     CDS             5019..6128
                     /locus_tag="ACGI5H_002711"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434155.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4Fe-4S binding protein"
                     /protein_id="HFG9698408.1"
                     /translation="MANLKVNLYGMEFLNPIMTAAGPGAKDGALCQEAAKGGAGAICT
                     KTISVLPADVPRPCMAKTNSGFLNTELWSELPKEQWIEEEYKKVKETGLPVIVSMGYS
                     AEQIAEVAPLVKPYADAVELSTHYVGTDVAPIVNALKAAKAVLDVPVFMKMSPHTDIQ
                     TIAKAVEEAGADGLVMINSFGPCMAIDVNTGYPIMGSKAGYGWLSGAPIRPLAIRCIY
                     EASQVVNIPIIGVGGITCGKDVAEMMMAGASAVQVCTEAILKGPSIYGKIAKELNEFL
                     DENGYADVNEIKGLTHKKMAARGFRTHSVAPVVDDNKCIKCKQCVTSCVYEALEVTDK
                     LNIDADKCFGCGLCVTRCPKGALSICYNQVEAMNE"
     gene            6411..7802
                     /gene="hydA"
                     /locus_tag="ACGI5H_002712"
     CDS             6411..7802
                     /gene="hydA"
                     /locus_tag="ACGI5H_002712"
                     /EC_number="3.5.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898309.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0004157 - dihydropyrimidinase activity
                     [Evidence IEA];
                     GO_process: GO:0008152 - metabolic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="dihydropyrimidinase"
                     /protein_id="HFG9698409.1"
                     /translation="MGIVLKGGKVVTSEKTYCADVRIEDEKIVDIGLDISKENDEIVD
                     VSDSYVIPGGIDTHTHFDLDTGVTKTADNFETGTKAAIVGGTTTILDFATQAKGCSLK
                     DGLEEWHEKAKDKSYSDYGFHMAITDWNDSVCNEMEDMVKEGVSSFKLYMAYKGSLQV
                     DDGVIFEALRKAEEIGGIIGFHCENGDIICELVDKAKSENNLSPKYHQLTRPAIMEAE
                     ATSRLMKIAEVANSKVYVVHLSCKESLEEVLKAKQRGVDVIVETCPQYLLLNDELYDL
                     DGFESAKYVMSPPLRNKENNEILWNAILDNQIDTIGTDHCSFNYKGQKELGINDFSKI
                     PNGSPGVEHRMSLLYTYGVCKNKISINKMVEVTSTNAAKLFGMYPNKGTIEIGSDADI
                     LVLNPNKKSKIEAKKQLQNVDYTPYEGYEVDCQIEHVYLRGKEVVRDGELICNTPSGR
                     YINRRLTKGAREW"
     gene            7796..10357
                     /gene="xdh"
                     /locus_tag="ACGI5H_002713"
     CDS             7796..10357
                     /gene="xdh"
                     /locus_tag="ACGI5H_002713"
                     /EC_number="1.17.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421967.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004854 - xanthine dehydrogenase activity
                     [Evidence IEA];
                     GO_function: GO:0043546 - molybdopterin cofactor binding
                     [Evidence IEA];
                     GO_process: GO:0046415 - urate metabolic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="selenium-dependent xanthine dehydrogenase"
                     /protein_id="HFG9698410.1"
                     /translation="MVEFILNGEKVVAKEGKKLLDFLREDMNITSVKNGCSEGACGTC
                     MVIIDGKATKACVFKTDKLAGKNITTIEGLSERERDVFAYSFASQGAVQCGFCIPGMV
                     ISSKALIDVNNNPTEDDIKKALKGNICRCTGYVKIIKAVDLAAKIFRENIDVPKVNCK
                     GLVGENLPRVDAVGKALGYSEYVDDMRIEGMIYGSAVRAKYPRALVKKIDIEEAKAYP
                     GVVAVLTAKDIPGTIKVGHLKKDWDTLIPEGEITRYLGDGIVLVAAETREALEEAKKL
                     VKIDYEELTPLSTTADALREDAPKIHETGNILVKEHLVRGNAKEKIENSKYVVTKRYT
                     TPATEHAFLEPECAVAGPYEDDGVIIYSTDQGVFATQHECADMLGLPYEKVRVINKMV
                     GGGFGGKEDMSVQHHAALLAYHTKRFVKVQLTRKESIIVHPKRHATEMEFTTACDENG
                     YLTGMKATIISDTGAYASLGGPVLQRLCTHAAGPYNYQDIDITGTAVYTNNPPGGAFR
                     GFGVTQSCFATECNLNLLAEMVGISPWEIRYKNAIRPGQVLPNGQFADEGTAMAETLE
                     AVKEEYEKHPRAGIACAMKNSGVGVGIPDVGRCRLVIKDGKVHIRTSASCIGQGLGTV
                     MTQVVCETANLLPENIVHEVPDTHLTPDSGNTTASRQTVFTGEATKVASNKLKEALDS
                     GKTLLDLEGEEFYGEYESITDKMGCDKENPVSHVAYGYATQVVILDENGKLEKVVAAH
                     DVGRAINPISLEGQIEGGVVMGLGYALTEDYPVVNSIPTAKFGTLGLFKSTDIPEIQA
                     LIVEKNKDLLAYGAKGVGEICTVPTAPAVQNAYYVFDKEFRTELPLQNTPYSKKK"
     gene            10509..11855
                     /gene="rpoN"
                     /locus_tag="ACGI5H_002714"
     CDS             10509..11855
                     /gene="rpoN"
                     /locus_tag="ACGI5H_002714"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421965.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016987 - sigma factor activity [Evidence
                     IEA];
                     GO_process: GO:0006352 - DNA-templated transcription
                     initiation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="RNA polymerase factor sigma-54"
                     /protein_id="HFG9698411.1"
                     /translation="MNFNNSLELTQSQKLIMTTQLKQSLSILNMSKLELEEEIKREAE
                     NNPLVEVEKSGEINWEEYIKDMDRSRRLDRTEISYNPDNEVNLENLVKYSSNLYEDLK
                     FQISLYKLTDKELEVCEYIIDSLDEDGYLRTEEKVIVDTLKIDEELFEKCLISVQQLE
                     PSGVGARSLSECLMIQMASLGIYNEILEEIVTKDLNLIANNKYKEISKKYNMSLQKCV
                     ELINIIKTLDPKPGRTCSVEKSVYIQPDVTVEKIDDEFIVYLNEKDSYQIRINSYYKD
                     ILKNSQSDESAKEFIKERLNSATGLMKNIESRKTTVLKIAEEIVKAQDEFLRKGTKYI
                     KPLKMKDIAEKLEFHESTISRGVNGKYMLTPFGVYEFRYFFSSAIETENNEMASSTSI
                     KKIIKETIKDENKKKPLSDDHISKLLKEKGINVARRTVAKYREELGIPSSSKRKEY"
     gene            12637..13659
                     /locus_tag="ACGI5H_002715"
     CDS             12637..13659
                     /locus_tag="ACGI5H_002715"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429564.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0030246 - carbohydrate binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sugar-binding transcriptional regulator"
                     /protein_id="HFG9698412.1"
                     /translation="MKNLLEIQKKLIPQAIELMERRYSILRQISLSEPIGRRTLSNVL
                     EISERIIRSETEFLKEQGLIDVAVSGMTITKEGSDLLDKLKDIMSDIMGLSKLQDRVR
                     EKLGIKRVILVPGSCDENGSLLKDVTRYGCEYFLGILKDGDIVSITGGSTMLEFSNVI
                     KTDKRYPNSTIVPARGSMGTDVEMQSNNIVASISKKLHSNCKLLHIPDELDESAMKTL
                     SQVPEIKTTLEYIKRTDILVFSIGRADVMAKRRKLPEDKVDEILSKNAVGEAFGYYFN
                     KDGEIVYKLNTVGIDLETVKQVKETIAIFAGTEKVEALLAISNMHKNMVLVTDEESAY
                     KILSLL"
     gene            13719..14726
                     /gene="gap"
                     /locus_tag="ACGI5H_002716"
     CDS             13719..14726
                     /gene="gap"
                     /locus_tag="ACGI5H_002716"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421962.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016620 - oxidoreductase activity, acting
                     on the aldehyde or oxo group of donors, NAD or NADP as
                     acceptor [Evidence IEA];
                     GO_function: GO:0050661 - NADP binding [Evidence IEA];
                     GO_function: GO:0051287 - NAD binding [Evidence IEA];
                     GO_process: GO:0006006 - glucose metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type I glyceraldehyde-3-phosphate dehydrogenase"
                     /protein_id="HFG9698413.1"
                     /translation="MVKVAINGFGRIGRLALRKMMEQQDKFEVVAINDLTDAKMLAHL
                     FKYDTAQGRFNGEIEVKEGAFVVNGKEIKVTAERNPADLPWAELGVDIVLECTGFFTS
                     KDKAEAHIQAGAKKVVISAPATGDLKTIVFNTNSDILDGSETVISGASCTTNCLAPMA
                     KVLNDKYGIEKGLMTTIHAYTNDQNTLDGPHPKGDLRRARAAAGNIVPNTTGAAKAIG
                     LVIPSLKGKLDGAAQRVPVVTGSITELVCTLGKNVTVEEINAAMKEASNESFGYTEEM
                     LVSSDIIGISYGSLFDATQTKVMEVDGKQLVKVVSWYDNEMSYTSQLIRTLGYFAQLA
                     K"
     gene            14948..16150
                     /gene="pgk"
                     /locus_tag="ACGI5H_002717"
     CDS             14948..16150
                     /gene="pgk"
                     /locus_tag="ACGI5H_002717"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429565.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004618 - phosphoglycerate kinase activity
                     [Evidence IEA];
                     GO_process: GO:0006096 - glycolytic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoglycerate kinase"
                     /protein_id="HFG9698414.1"
                     /translation="MSMLNKKTIEDIDVCGKKVLVRCDFNVPLQDGVITDENRLNGAL
                     PTIQYLISKGAKVILCSHLGKPKGEAKPELSLAPVAKRLSEMLGKEVVFAADDNVVGE
                     NAKKATEKMENGDVVLLENTRYRKEETKNEENFSKELASLAEIFVNDAFGTAHRAHCS
                     TVGAGEFLQERVCGYLIQKELKFLGEAVANPVRPFTAILGGAKVSDKLAVINELLEKV
                     DNLIIGGGMAYTFLKAQGYEVGTSLLEIDKVEYAKEMMEKAKNKGVNLLLPVDVVMAD
                     HFAPDATPIVTEDANVKEDYMGLDMGPKTIANFVKTIKESKTVVWNGPMGVFEFENFA
                     NGTLSVARAMAELTDATTVIGGGDSAAAVNQLGFGDKMTHVSTGGGASLEFLEGKELP
                     GIAALDNK"
     gene            16176..16919
                     /gene="tpiA"
                     /locus_tag="ACGI5H_002718"
     CDS             16176..16919
                     /gene="tpiA"
                     /locus_tag="ACGI5H_002718"
                     /EC_number="5.3.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891583.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004807 - triose-phosphate isomerase
                     activity [Evidence IEA];
                     GO_process: GO:0006096 - glycolytic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="triose-phosphate isomerase"
                     /protein_id="HFG9698415.1"
                     /translation="MRKPIIAGNWKMHKTIKEALEFVNEVKDKVNSDKVEAVICAPFT
                     LLKDLKEATKGTNIKIGAQNMHFEEKGAFTGEVSPLMLKEIDMDYVVIGHSERRQYFN
                     ETDETVNKKVLKALEVGIDPILCVGETLEQREAGKTKDVCKVQVEKALENVLKDDLAK
                     VVVAYEPIWAIGTGKTATAEDANDVISYIREVIKGLYGELANEVRIQYGGSVKPSNVA
                     EIMGQSDIDGALVGGASLASNDYLDLVNF"
     gene            16931..18460
                     /gene="gpmI"
                     /locus_tag="ACGI5H_002719"
     CDS             16931..18460
                     /gene="gpmI"
                     /locus_tag="ACGI5H_002719"
                     /EC_number="5.4.2.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429567.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0046537 -
                     2,3-bisphosphoglycerate-independent phosphoglycerate
                     mutase activity [Evidence IEA];
                     GO_process: GO:0006096 - glycolytic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="2,3-bisphosphoglycerate-independent
                     phosphoglycerate mutase"
                     /protein_id="HFG9698416.1"
                     /translation="MKKPVALIIMDGFGYNKDVKGNAIAESKTPNLDRIKKEYPNTLI
                     NASGLDVGLPDGQMGNSEVGHTNIGAGRIVYQDLTRITKSIKDGDFFTNKVLCEAMDN
                     AKENSLHVMGLLSDGGVHSHIDHLKAIIKMAKDKGVQKVYVHAFTDGRDTDPQSALEY
                     AKEVQASMDEIGVGEFATVSGRYYAMDRDKRWERVELAYNAMVRGIGEKANSIEEAIQ
                     NSYDDGKNDEFIMPTVIMKDDKPVGSIKENDSIIFFNFRPDRARQITRALVCEEFDGF
                     KREDIKNFFVCLTEYDITIENVHIAFGPQSLANTLGEYLAKNGKTQLRAAETEKYAHV
                     TFFFNGGVEEPNKGEERLLIPSPKVATYDLKPEMSAYELTDKALDKLGEDKFDFIVLN
                     FANPDMVGHTGSIEAAIKAVETVDTCVGRLIDKIVELGGSAIITADHGNAEYMLDPET
                     GKTVTAHSINPVPFIVVGQEYESAKLLDGGRLSDIAPTILDMMKLEKPEEMTGHSLIS
                     K"
     gene            19048..20340
                     /gene="eno"
                     /locus_tag="ACGI5H_002720"
     CDS             19048..20340
                     /gene="eno"
                     /locus_tag="ACGI5H_002720"
                     /EC_number="4.2.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898301.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0000015 - phosphopyruvate hydratase
                     complex [Evidence IEA];
                     GO_function: GO:0000287 - magnesium ion binding [Evidence
                     IEA];
                     GO_function: GO:0004634 - phosphopyruvate hydratase
                     activity [Evidence IEA];
                     GO_process: GO:0006096 - glycolytic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphopyruvate hydratase"
                     /protein_id="HFG9698417.1"
                     /translation="MSVIELVYAREVLDSRGNPTVEVEVVLEDGAMGRAIVPSGASTG
                     AFEAVELRDGDKGRYLGKGVETAVANVNEIIAPEIEGMDAFDQPAIDAIMIELDGTPN
                     KGKLGANAILGVSMAVARAAADEIGLPLFQYLGGVNAKQLPVPMMNILNGGEHADNNV
                     DVQEFMILPVGACCFKEGLRMGAEVFHSLKKVLGEKGLACGVGDEGGFAPNLGSNREA
                     LELIVEAITKAGYKPGEDVMLGLDVAATEMYNKETKKYVLAGEGKELTAAEMVALYED
                     WSNNFPIITIEDGLDEEDWDGWKLLTEKLGNKLQLVGDDLFVTNTERLEKGIENGVAN
                     SILVKVNQIGTITETLDAIEMAKRAGYTAVISHRSGETEDSTIADLAVAVNAGQIKTG
                     APSRTDRVAKYNQLLRIEEMVGEQARYCGLKSFYNLKK"
     gene            20933..21157
                     /gene="secG"
                     /locus_tag="ACGI5H_002721"
     CDS             20933..21157
                     /gene="secG"
                     /locus_tag="ACGI5H_002721"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421948.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0015136 - sialic acid transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0015739 - sialic acid transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecG"
                     /protein_id="HFG9698418.1"
                     /translation="MSNILMGVQVVLGILLVISIMPQDSKNALPSEFGGEGSQAYFKP
                     KGKQAFLARVTKITAVLFFINALALLIVKK"
     gene            complement(21541..22479)
                     /locus_tag="ACGI5H_002722"
     CDS             complement(21541..22479)
                     /locus_tag="ACGI5H_002722"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861865.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="AEC family transporter"
                     /protein_id="HFG9698419.1"
                     /translation="MENLILSINVVLPLFLTMSLGYVLKKLGLFDTHTLNKMNNVCFK
                     SFLPLLLFFNIYNTDLDGSLNFKLMAVAVIIIFSIFLILVFIIPKIEKDNKTRGALIQ
                     GVFRSNFVIFGIPVTISLFGDKSIGVTSLLIAVIVPMFNVLSVVILEIFRGGKVNIKH
                     MIKSVLTNPLIIASFIGLTMLILNINIPTFLHKTIGDISKIATPLSLIILGGSFSFSA
                     IKGHIKPIILGVCGKLILVPAIFLPISIFLGFRNVELASLMIMLSAPTAVSSFTMAQQ
                     MDSDSELAGQIVVFTSGFSIITVFLIIFILKQNNLI"
     gene            complement(22467..22865)
                     /locus_tag="ACGI5H_002723"
     CDS             complement(22467..22865)
                     /locus_tag="ACGI5H_002723"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434143.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HFG9698420.1"
                     /translation="MIKKIEHVVITNNNIENYINFYKKFGFSSKEMSKNYKLNARNVK
                     INLNIKGYKFLPYVKNSKASRDNLCFKINTNIDEPKKYLEQNEIQIKRGIVECTGVFG
                     NMKSIYLKKTNGNLIELSNHRITESKPWKI"
BASE COUNT         9126 a         2624 c         4433 g         6770 t
ORIGIN      
        1 gttgaaaaag ctgattgcta tacaggaaat actatagaaa gtgaaagatt cttcccaggt
       61 tggctatatg atgaagaaga tgaatttgtt caagcagcgt ataagggatt aaaagaagct
      121 ggaatagatt cagaaataac tcaatactca ttctgtacga atggaagtca ctacgcaggt
      181 gaggctggaa taagaactat aggatttggt ccttctaagg aaaatcttgc tcatacaata
      241 gatgagtata tagaattaga ccaattattc aaaggtgcag aaggatatta tggtatatta
      301 aaatcagttt ataaaaaata attaggagat ggttttgtga gaattttaat aaaacatggg
      361 cttatagtag atggaaataa aacaccagca tatgaaggag atattttaat agaaaacgag
      421 aaaatattaa aaatatcaca agatttaaac gaagaagctg acaaagttat agatgcaaaa
      481 ggtagagtta tatgtccagg tttcatagat actcatagcc attcagacct agttatttta
      541 gttaatccat ataatgaggt aaagattaga cagggaatta caacagaagt gttgggccaa
      601 gatggtatat ctatggcccc tctacctcaa gagcatatat cttcttggag aaaaaattta
      661 gcaggtctag atggtgaaag tgatgaaatt gattggaaat atgaaacaac agagaattat
      721 ttaaaaatga tggattacaa tggggtaggt ttaaatgaaa cttatttagt acctcatgga
      781 aacgttagaa tggaagctat gggacttgaa gatagacctg ctactaaaga agaaattcaa
      841 aaaatgtgtg aaatcacaga gagagaatta aaagcaggag ctataggatt gtctactgga
      901 cttatatata taccttgtgc atactcattg actgaagaaa ttatagagat gtgtaaggta
      961 gtagcaaaat atgatggagt atttgtagtt caccaaagaa gtgaagcaga tacaatttta
     1021 acttcaatgg aagaaatcat agaaattgga aaacaatcag gagtaaaagt tcatttttca
     1081 cattttaagg tttgtggtaa agcaaactgg aagtatatac cacaagttat agagctttta
     1141 gaaaaagcag aaaaggaagg aataagagta tcttttgacc aatatccata tgcagcagga
     1201 agtacaatgc ttggagtagt tttacctcct tgggcacatt ctggaggaac tgataagtta
     1261 atagaaagat taagtgatga aaacgaaaga gcaaaaatga aaaaagatat agcaaatgga
     1321 atagaaggct gggataattt tatagaattt gctggaatag accaaatatt tgtaacaagc
     1381 gtaaaaacag aaaagaataa agatacaatt ggtaagaact tattagaaat tggaaaaatg
     1441 agaggaaaag acccattaga tgcaacgttt gatttattaa aagaagaaga aaatgcagtt
     1501 gggatggtag atttctatgg attagaagaa catataatag gattcatgaa aagagacgag
     1561 caaaatgtgt gtacagatgg tcttttagca ggtaaaccac atccaagagc ttatggttct
     1621 ttccctaaaa tactaggaag atatgttaga gagttgaatg tgttaacaat cgaagaagct
     1681 gtttataaaa tgactaaaaa ggcagctaca agctttagta taaaagatag aggcgaatta
     1741 aaagaaggat attttgcaga tatagttata tttgacaagg atacagttag tggttgtgat
     1801 gattttatca actctatgca gtaccctaca ggtatagatt acgtaattat aaatggaaat
     1861 tgtgttgttg aagaaggaaa atacaataaa attaaagcag gaaaagtact taaaaattaa
     1921 atcttagctt taaggaggaa taaatttatg attttagtgg ggaatgggag gctaataagc
     1981 caagattctt taaatcccta tatggaagat ggatgtgtag taataaatga taatctaatt
     2041 gaagatatag gtactacaga agaaatgaaa gctaaatatc cagtacatga atttatagat
     2101 gcaggcaaga aaataatcat gccgggtcta ataaattcac atatgcatat atacagctca
     2161 tttgctagag gaatggcagt tccaggaaaa ccttctgaga actttttaga gatactaaac
     2221 aatttatggt ggagacttga caaacagctt acactggaag atacaaaata cagtgcatat
     2281 gcaacgtata tagaatgtat aaaaaatggt gtaacaacag tttatgacca tcatgcaagt
     2341 ccaaatgcaa ttgaaggcag tttgtttaca atatcagatg ttgcaaagga tttgggaatt
     2401 agaacgtgtc tttgttatga agtgtctgat agagatggtg gaaatacaat ccaacaaggt
     2461 atcaatgaaa acgtaaactt tataaaatac gctcaaaaag atgatacaga catgataaaa
     2521 ggaatgtttg ggcttcatgc tgcatttaca ctatctgatg atacattaaa taaatgtgct
     2581 tcagagatgg ctggtcttga tacaggttac catgtacatg ttgctgaagg actagcagac
     2641 ttacaatata atgtagataa atatggaaaa agggttttag aaagattcaa tgattttgga
     2701 gtactaaaag aaaaaacaat agcagttcat tgtatatata taagtgcaga agaaatcagt
     2761 cttttaaata aaacaaatac atttgtagtt cataatccag aatctaatat gggaaatgca
     2821 gttggatgtt ctcctgcaat agagttatta aaaaggggag ttacagtagg attaggaact
     2881 gatggatata ctagcgatat gtttgaatca ttaaaagttg ccaatataat tcacaaacat
     2941 cacttaaaag acccaagagt tggatttgaa gaatcacaaa caatgttatt tgataacaat
     3001 agaaaaatag ctaaagctta ttataaaaat gacctaggag tacttaaaaa aggtgcttat
     3061 gcagatgtta tagtagttga ttatatacca catactccat tgacagaaaa tacaataggg
     3121 ggacacacta tttttggaat gagtggaaga agcgtagata caactattat aaatggaaag
     3181 gtacttatga aagatagaaa gttaataaac atagatgaag aaagtattct agcaaaaagt
     3241 agagaattaa gtcaaaatct atggaataga atttaaataa ttgattatgc aaaattctat
     3301 gaagcaggaa ccctgtgact ttagtcatgg gaggttcaga ttaatataca agtaagaaac
     3361 aagaatttag atgttaaaaa cagagcttaa acaaaaatag gaatttaaat gaagtatata
     3421 aataaaaaat atacggaata gaatattaaa ttaaatatag aagggagacc caaaatgtct
     3481 cgagataaaa gccctaaaat agctccagta gatgaaaggt tacctgtatc caaatcttgg
     3541 gtattttcac tacagcacgt tttagcaatg tgtgcaggag cagtagcagt tcctatgatg
     3601 ataggaagtg ctgcacgact agatcatgct agtattgttt ttttaataaa tgcttgcttg
     3661 tttatggcag gtataggaac actcatacaa agtgttggta taggaaatat tgtaggtgct
     3721 aaaataccag taatagaagg aactagtttt gccgctgtgg caggtatgac agcaatagcc
     3781 tcatcatata gtgattcaca agttgcaata cagacagtat ttggctctgt aatagtagct
     3841 ggattgtttt gtatattact tgctccagta tttgaaaaat taataagatt tttccctagt
     3901 gtagttactg gaacagttgt tatggtaata ggtatttcac tatttccagt tgggataaaa
     3961 tggataactg acaacaaatt ggaagcggtt gaaccaaact cattagcatt agctttagca
     4021 gtattggcaa taactttact ttcatttaaa ttcttaaaag gaatttggaa tagcacagct
     4081 atattggtag gtatagtact tggtacacta ctttccatgg cagttggaat ggcagatttt
     4141 agtgcagtaa atggagttgg ttggcttaac ttaaatgtac ctttaaaatt tggaatgcct
     4201 agatttgaac catctgcaat actatcattg tgtttgatta tgttggtact tatgacggaa
     4261 tcagttggta atatgatagc tattcatgaa atggtagaca aagaagtaac aggtaaaaat
     4321 attaaaagag gtctatttgg agatggaata tctacagcat tatctggaat attcaattca
     4381 tttccaataa ctccatttgg tcaaaataca ggaatagtag gtcttacagg tataaaatca
     4441 agatttatag cagtttacgc aggggttata ttgctagtac ttggattctt accaaaattt
     4501 gcagcaataa taggagcaat acctaagcct gttcttggag gcgtaggatt tgcaatgttt
     4561 ggaatggtaa tggttggagg agtaaaaact ttaagcaaag tgaaatttga tggaactaaa
     4621 aatggggtta tagtagcagt tagtgttggt ttgtctatga taccactaac aaatcctgat
     4681 ttctatcata atttcccaac ttgggtacaa acaatattcc atagtggaat aacaacaggt
     4741 agtttatcag cagtgctttt aaacatattc ttcaatgaac taggttctaa aaaagaaaaa
     4801 aataataaag ttgaagaagc aaaataaaaa taaaacaagt aaaaatctat attgacttaa
     4861 agtcattaag tattaataaa aataattcag agatattaat aattcaacaa aactatctta
     4921 tattttaaat aatataaaaa agtaaataaa taacaaatac aaataaaaga atacaatcta
     4981 aatattaaaa atatttaatt taagggagag ataataatat ggctaattta aaagttaatt
     5041 tatatggaat ggaattttta aatccaatta tgacagcagc aggacctgga gcaaaagatg
     5101 gtgctctctg tcaagaggca gcaaaaggtg gagcaggagc tatatgtaca aaaactatat
     5161 ctgtattacc agctgatgta ccaagaccat gtatggcaaa aactaatagt ggttttttaa
     5221 acacagaatt atggtcagag cttccaaaag agcaatggat agaggaagaa tacaaaaagg
     5281 taaaagaaac agggcttcca gtaatagtaa gtatgggata ttcagcagag caaatagctg
     5341 aggttgctcc tttagtaaag ccttatgcag atgcagttga attatctact cattatgtag
     5401 gtacagacgt tgcaccaata gtaaatgctt taaaagctgc aaaagctgtt ttagatgtac
     5461 cagtatttat gaaaatgagt cctcatactg acattcaaac tattgcaaaa gctgttgaag
     5521 aagcaggtgc agatggactt gtaatgataa actcatttgg accatgtatg gcaatagatg
     5581 taaatacagg ataccctata atgggaagta aagctggata cggatggtta tcaggtgcac
     5641 caataagacc tctagcaata agatgtatat atgaagcttc tcaagttgta aatataccaa
     5701 taatcggtgt tggtggaatc acttgtggaa aagacgtggc tgaaatgatg atggctggag
     5761 caagtgctgt tcaagtatgt acagaagcaa tccttaaagg gccttctatc tatggaaaaa
     5821 ttgctaaaga attaaatgaa tttttagatg agaatggata tgctgatgtt aatgaaataa
     5881 aaggactaac tcataagaaa atggcagcta gagggtttag aactcattca gtagctccag
     5941 tagtggatga taacaagtgt atcaaatgta agcaatgtgt aacaagctgt gtatacgaag
     6001 ctttagaagt tacagataag ttgaacatag atgcagacaa gtgttttgga tgtggattat
     6061 gtgtaactag atgtccaaaa ggagctttaa gcatctgcta caatcaagta gaagctatga
     6121 atgagtaata attatataga attttggtaa ttaacttaga gtaataggta ttaggataat
     6181 aaaatatatc agataaacaa acacacatta tgcattaata atacagtcta aagttaataa
     6241 ttttattata ttgatttaac taaatattag tttagctgaa tattaattta attaggtatt
     6301 ggtttaatct taatatagat ttactgcgta taagtgaact aactagatta ctttaagtta
     6361 attttttcat ataaaataaa ttgatacatt acaagtaagg tggagtctat atgggaattg
     6421 ttttaaaagg tgggaaagta gtaacaagtg aaaaaactta ctgtgcagat gtaagaatag
     6481 aagatgaaaa aatagtcgat ataggtcttg atatatcaaa agaaaatgat gaaatagttg
     6541 atgttagtga ttcttatgtt ataccaggag gtatagatac acacacacac tttgacttag
     6601 atacaggcgt tactaagaca gcagataact ttgagacagg aacaaaagct gctatagtag
     6661 gaggaactac tactatattg gattttgcta cacaagctaa aggatgttct ttgaaagacg
     6721 gattagaaga atggcatgaa aaagctaagg ataaatccta ttcagattat ggctttcata
     6781 tggctataac agattggaat gactcggttt gtaatgaaat ggaggatatg gtgaaagagg
     6841 gagtatcttc atttaaactg tatatggcgt ataaaggaag ccttcaagtt gatgatggtg
     6901 taatctttga agcattgaga aaagcagaag agataggagg gattattggt ttccattgtg
     6961 aaaatgggga cataatatgt gaacttgtgg ataaagcaaa gtcagaaaat aatttatctc
     7021 caaaatatca tcaattaact agaccagcta taatggaggc agaagctaca tcaagactta
     7081 tgaagatagc tgaagttgca aactctaaag tatatgtagt tcacttaagc tgtaaagaat
     7141 ccttagagga ggttttaaaa gctaagcaaa gaggtgtgga tgtaatagtt gaaacttgtc
     7201 ctcaatacct tctattaaat gatgaattat atgatttaga tggatttgaa agtgctaagt
     7261 atgtaatgtc accaccttta agaaataaag aaaataatga aatattatgg aatgctattt
     7321 tagataatca aatagacact ataggaacag accattgttc ttttaattat aagggacaga
     7381 aggaacttgg gataaacgat ttcagtaaga taccaaatgg ttctccaggt gtagaacata
     7441 ggatgagtct tttatacaca tatggagtct gtaaaaataa aatatctatc aacaagatgg
     7501 tagaagtaac atcaactaat gcagcaaagt tgtttggaat gtatcctaat aaaggaacta
     7561 tagaaatagg cagtgatgca gatatattag tcttaaatcc aaacaaaaaa tccaaaatag
     7621 aagcaaaaaa acaattacaa aatgtagatt atacacctta tgaagggtat gaagtggatt
     7681 gtcaaataga acatgtttat ttaagaggaa aagaagtagt tagagatgga gaattaattt
     7741 gtaatactcc aagtgggaga tatataaata ggcgtctaac aaagggggct agagaatggt
     7801 agaatttata ttaaatggag agaaagttgt tgcaaaagaa ggcaaaaaac ttttagactt
     7861 ccttagagaa gatatgaata taacttcagt taaaaatgga tgttcagaag gtgcttgtgg
     7921 aacatgtatg gttataatag atggtaaagc tactaaagca tgtgtattta aaactgataa
     7981 attagctggg aaaaacataa caactataga gggattatca gagagagaaa gagatgtttt
     8041 tgcatattct tttgctagtc aaggagctgt acaatgtgga ttttgtattc caggtatggt
     8101 aattagttca aaagcactta tagacgttaa taataatcct actgaagatg atataaagaa
     8161 agctttaaaa ggtaatatat gtagatgtac agggtatgta aaaataatta aagctgtcga
     8221 tttagcggca aagattttta gagaaaatat agatgtgcca aaagtaaact gtaagggtct
     8281 agtaggtgaa aatcttccta gagttgatgc agttggcaaa gcacttggat attctgaata
     8341 tgtagatgat atgagaattg agggtatgat ttatggttca gcagttagag ctaagtatcc
     8401 tagagcttta gttaaaaaaa tagatataga agaagcaaaa gcttatccag gagttgttgc
     8461 agttctaaca gctaaagata ttccaggaac tataaaggta gggcacttaa agaaggattg
     8521 ggatacttta ataccagaag gtgaaataac tagatactta ggagatggaa tagttttagt
     8581 agcagcagaa actagagaag cgttagaaga ggccaaaaag ctagttaaga tagattatga
     8641 ggaattaaca ccattaagta ctacagcaga tgcacttaga gaagatgctc caaagataca
     8701 tgagacaggg aatatacttg ttaaggaaca tttagtaaga ggaaacgcta aagaaaagat
     8761 agaaaattca aaatatgttg taactaaaag atatactaca cctgctacag aacacgcatt
     8821 tttagagcct gaatgtgcag tagctggtcc ttatgaagat gatggagtaa taatctattc
     8881 gacagaccaa ggggtgtttg ccactcaaca tgaatgtgca gatatgttag ggttaccata
     8941 tgagaaggta agagttataa acaaaatggt aggaggaggg tttggtggaa aagaagacat
     9001 gagtgttcaa caccatgcag ccttacttgc ataccataca aagagatttg taaaagtaca
     9061 gttaacaaga aaagaaagta ttattgttca tccaaaacga catgccacag aaatggaatt
     9121 tacgacagca tgtgatgaaa atggatactt aacgggtatg aaggcaacga taatatctga
     9181 cacaggtgca tatgcctctc ttggaggacc agtgctacaa agactgtgta ctcatgcagc
     9241 aggaccatac aattatcaag atattgatat aacaggaaca gcagtatata ctaataaccc
     9301 tcctggagga gcatttagag gatttggagt tacacagagt tgttttgcaa ctgaatgtaa
     9361 tctaaattta cttgctgaaa tggttggaat atctccttgg gagataagat ataaaaatgc
     9421 aataagacct gggcaagttt taccaaatgg tcaatttgca gatgaaggaa cagcaatggc
     9481 agagacacta gaagctgtaa aagaagagta tgaaaagcat ccacgtgcag gtatagcttg
     9541 tgctatgaaa aatagtgggg ttggagttgg tatacctgat gttggaagat gtagattggt
     9601 gataaaagat ggcaaagttc acataagaac aagtgcttct tgtataggtc aagggcttgg
     9661 tactgttatg actcaagtag tttgtgaaac tgctaaccta cttcctgaaa atatagttca
     9721 tgaagttcca gatactcatt taacaccaga ctctggtaat actacggctt caagacagac
     9781 agtatttacg ggagaagcta ctaaggttgc atcaaataag ttaaaagaag ctttagactc
     9841 tggcaaaact ttacttgatt tagagggaga agagttttat ggagaatatg aaagtattac
     9901 agataaaatg ggttgtgaca aagaaaatcc agtaagtcat gttgcttatg gatatgcaac
     9961 acaagttgta attctggatg aaaatggaaa actagaaaaa gtagtagcag cacatgatgt
    10021 tggaagagct ataaatccaa tcagtttaga aggtcaaata gaaggtggag tagttatggg
    10081 tcttggatat gctctaaccg aagattaccc agtagttaac tctattccta cagctaagtt
    10141 tggtacatta ggtttattta aatctacaga tataccagaa atacaagctt taatagttga
    10201 aaagaacaaa gatttattgg cttatggggc aaaaggtgta ggagaaattt gtacagttcc
    10261 tactgcacca gcagtacaaa atgcctatta tgtatttgat aaagaattta gaactgagtt
    10321 accactacaa aatactccat atagtaaaaa aaagtaacaa aaaaaagaaa tattaaataa
    10381 aaaaatagat gaaattgtaa ataaaaaaaa cccttttgca taaggtatat tttaaatgat
    10441 agaatataca tatacaggag ggtttttctt ttataaaata agtttaataa aattgagagg
    10501 tgagcagaat gaattttaat aatagtctag aattaactca gtctcagaag ctaataatga
    10561 ctacacaact taagcaatca ttatcaatat taaatatgag taagttagag ttagaagaag
    10621 agataaaaag agaagcagag aataacccat tagttgaagt cgagaaaagt ggggagataa
    10681 attgggaaga gtatataaaa gacatggata ggtcaagacg tttagataga acagagataa
    10741 gctataatcc tgataatgaa gttaatctag aaaatttagt taaatattcg tcaaatttat
    10801 atgaagattt aaaatttcag ataagcctgt ataaacttac agacaaagaa ttggaagtct
    10861 gtgagtatat aattgatagt ttagatgagg atggatattt aagaactgag gaaaaagtaa
    10921 ttgttgatac cttaaagata gatgaagaac tttttgaaaa atgtttaatt agtgttcagc
    10981 agttggaacc tagtggagta ggggcaagaa gtctttcaga atgtctgatg atacaaatgg
    11041 ctagtttagg aatatataat gaaattttag aggaaatcgt tacaaaagac ttaaatttaa
    11101 ttgcaaataa taaatacaaa gagataagta aaaagtacaa tatgtcatta caaaaatgtg
    11161 ttgaactaat aaatataatt aagacattag accccaaacc aggaagaact tgttcagtag
    11221 agaaaagtgt atacattcaa cctgatgtaa cagtagaaaa aattgatgat gaatttattg
    11281 tatatttaaa tgagaaagat tcttatcaaa taagaatcaa tagttattat aaagacatat
    11341 taaaaaattc acagtctgat gaaagtgcaa aagaatttat aaaagaaaga ctaaattcag
    11401 caacaggact tatgaaaaat atagagagta ggaaaactac agtacttaag attgcagaag
    11461 agatagtaaa agctcaagat gaatttttga gaaaagggac aaaatatata aaacctttga
    11521 aaatgaaaga catagcagaa aaattagaat ttcatgaatc tactataagt agaggtgtaa
    11581 atggtaaata tatgctaaca ccttttggcg tatatgaatt taggtacttt ttcagtagcg
    11641 ccattgagac tgagaataat gaaatggcat ctagtacaag cataaaaaaa attataaagg
    11701 aaacaataaa agacgaaaat aaaaagaaac ctttaagtga tgaccatata tctaagttat
    11761 taaaagaaaa aggaatcaat gttgcaagaa ggacagttgc caaatatcgt gaagaattag
    11821 gaatcccatc ttcaagtaag agaaaagaat actaataagt aaaagacaaa tatcagtatg
    11881 gtaaggggaa aaggctaatt aagagatgaa tgtagattgg gctaaaaatt ttataaagta
    11941 aaataatata atatgaaaaa gtattaaaat gctataaggt attaaaaaac tggggaacat
    12001 taaaacatta agatagcaaa gagcataaaa aactaaagaa gattaaaaca ttaaagaaca
    12061 ttagagcttt gaggaatatt agaactttaa agaatattaa aatttataaa atataaaaat
    12121 actaaaaaga attgaaaaac tggggaacat taaaatattg taaaatgcta aaaaactaga
    12181 aaacataatt aaataagtgc ttataaagaa tgattaaatt aaataagtgt ttgtaaagaa
    12241 taattagata ttagaaaaag aagaatacct agataaataa actattatta aatttaataa
    12301 tcacaaaagg aaaacacgta gggtataaat aaaaatctta actagataaa agtaaactta
    12361 gttgtagata aaaataacta gaaataaaat tatttatagt aataaatatt agaatgaaaa
    12421 tataaaaaaa tatatataaa aagccttata taaaaagaaa aaatactgtg atttgaaaat
    12481 ggtggagaaa tattttataa aataaaaaaa taaaaaagtt tttgaaaaac tattgaaatc
    12541 tatacgcaaa tcctataaaa taaaaatatc ttgtgggact taaataaaca ctagggacaa
    12601 aaaaagtccc gaaaggaaag caataaggag tatgttatga agaacttatt agaaattcaa
    12661 aagaaattga ttccacaggc aattgaactt atggaaagaa gatactctat tttaagacaa
    12721 atatctttaa gtgaaccaat aggtaggaga acattatcaa atgtattaga gattagtgaa
    12781 agaataatca ggtcagaaac tgagttttta aaagaacaag gacttataga cgtagctgta
    12841 tctgggatga ctatcactaa agaaggttct gatttgttag ataaacttaa ggacatcatg
    12901 agtgacatca tgggattgtc taagttacaa gatagagtca gagaaaagct tggaataaaa
    12961 agggtaatat tagttcctgg aagctgtgat gaaaatggaa gtttactaaa agatgtaact
    13021 agatatggat gcgaatattt cttaggcatt ttaaaagatg gagatatcgt ttcaataaca
    13081 ggaggaagca ctatgttgga gttttcaaac gttattaaaa ctgataagag atatccaaac
    13141 tctacaatag ttccagctag aggaagtatg ggaactgatg tagagatgca atctaacaat
    13201 atagttgctt caataagtaa gaaattacat tctaattgca aacttttaca tataccagat
    13261 gagttggatg aaagtgcaat gaaaactctt agccaagtgc cagagattaa gacaactttg
    13321 gagtatatta aaagaacaga cattttagtt tttagtatag gtagagcaga tgtcatggca
    13381 aagagaagaa aacttccaga agacaaggtt gatgagatat tatctaaaaa tgcagttgga
    13441 gaagcatttg gatattattt caacaaagat ggagaaatag tttacaaact gaacactgtt
    13501 ggaattgatt tagaaacagt taaacaagta aaagaaacta ttgcaatctt tgcagggact
    13561 gaaaaagtag aagccttatt agctatatca aatatgcata aaaacatggt tcttgtaaca
    13621 gatgaagaaa gtgcttataa gatattgtca ttattataaa agtcaagacc tagcacagag
    13681 ctagaaaaca tacatttact ttataggagg tagcgaaaat ggttaaagta gctataaatg
    13741 gatttggaag aataggaaga ttagcattaa gaaaaatgat ggagcaacaa gataagttcg
    13801 aagttgttgc aataaacgac ttaacagacg ctaaaatgtt agctcattta tttaaatatg
    13861 atacagctca aggaagattt aacggagaaa tagaagttaa agaaggtgct tttgtagtaa
    13921 acggaaaaga aataaaagta acagcagaaa gaaatcctgc tgacctacca tgggctgaat
    13981 taggagtaga tatagtatta gaatgtacag gattctttac atctaaagat aaagctgaag
    14041 ctcatataca agcaggggct aagaaagttg ttatatctgc accagctact ggagatttaa
    14101 aaacaatagt attcaacaca aacagtgaca tattagatgg ttctgaaaca gttatatcag
    14161 gagcttcttg tactactaac tgtttagctc caatggctaa agtattaaat gataaatacg
    14221 gtatagaaaa aggcttaatg actactatac atgcatacac taatgaccaa aatactttag
    14281 atggtcctca tccaaaaggt gatttaagaa gagctagagc tgctgctgga aacatagttc
    14341 caaacactac aggagctgca aaagcaatag gcttagtaat accttcatta aaaggaaaat
    14401 tagatggggc agcacaaaga gtaccagttg taactggttc aataactgaa ttagtttgta
    14461 cattaggaaa aaatgttaca gttgaagaaa taaatgcagc tatgaaagaa gcttcaaacg
    14521 aatctttcgg atatactgaa gaaatgttag tatcttctga cataatcgga ataagctacg
    14581 gttcattatt tgacgctact caaacaaaag ttatggaagt agatggaaaa caattagtta
    14641 aagttgtttc ttggtatgat aatgaaatgt cttatacttc tcaattaata agaactttag
    14701 gatactttgc acaattagca aaatagtcag ttttgagaaa atagaaaagt agattgacaa
    14761 agtccgagtt tgtagtttaa tactacggac tcaggacttt ttttaagaaa aaatatataa
    14821 aatacaccta aataatgtta catactatat ataaaaatat gataatatga tatatttaat
    14881 agggtaaaag tatgtactat attatacttg gcaataaaaa attactttat taaaaggaga
    14941 gatatttatg tcaatgctta acaaaaaaac tatagaagat attgatgtgt gcggaaaaaa
    15001 agtattagta agatgtgact ttaatgtgcc attacaagat ggtgtaatta ctgatgaaaa
    15061 tagattgaac ggagctttac caactattca atatttaatt tctaaagggg caaaagttat
    15121 attatgctct cacttaggaa agccaaaagg agaagctaaa ccagaattat ctttagcacc
    15181 agtagcaaag agattatctg agatgttagg aaaagaagtt gtatttgcag cagacgataa
    15241 tgttgtagga gaaaatgcaa agaaagcaac tgaaaaaatg gaaaacggag atgtagtatt
    15301 attagaaaat actagatata gaaaagaaga aactaaaaac gaagagaatt tctctaaaga
    15361 actagcatca cttgctgaaa tatttgtaaa tgatgcattt ggaactgctc atagagcaca
    15421 ttgctcaaca gttggtgcag gcgagttttt acaagagaga gtttgtggat acttaattca
    15481 aaaagaatta aaattcttag gagaagctgt tgcaaaccct gtaagaccat ttacagctat
    15541 acttggagga gctaaagttt ctgataaatt agctgttata aacgaattat tagaaaaagt
    15601 tgataatcta ataataggtg gaggaatggc ttatacattc ttaaaagctc agggttatga
    15661 agtaggaact tctttacttg aaatagataa agttgaatat gctaaagaaa tgatggaaaa
    15721 agctaagaat aagggtgtta acttattatt accagtagac gttgttatgg cagaccactt
    15781 tgcaccagat gctactccaa tagtaacaga agatgctaat gtaaaagaag attacatggg
    15841 actagatatg ggacctaaga ctatagcaaa ctttgtaaaa actataaaag aatcaaaaac
    15901 tgtagtatgg aatgggccaa tgggagtatt tgaatttgaa aactttgcaa atggtacatt
    15961 atcagtagct agagctatgg cagagttgac tgatgcaact actgtaattg gcggtggaga
    16021 tagtgcagca gcagttaatc aattaggatt tggtgacaag atgactcacg tatcaacagg
    16081 tggaggagca tcactagaat ttttagaagg taaagaatta ccaggtattg cagcattaga
    16141 taataaataa actaatatat agaggagatt gtaaaatgag aaaacctata attgcaggaa
    16201 actggaaaat gcataaaaca ataaaagaag ctttagaatt tgtaaatgaa gttaaagata
    16261 aagtaaattc tgataaagta gaagctgtta tatgtgcacc atttacttta ttaaaggatt
    16321 taaaagaagc tactaagggt acaaatataa agataggtgc tcaaaatatg cactttgaag
    16381 aaaaaggagc atttacagga gaagtttcac ctcttatgtt aaaagaaata gatatggact
    16441 atgttgtaat aggacattca gaaagaagac aatacttcaa tgaaactgat gaaactgtaa
    16501 acaagaaagt tttaaaagca ttagaagtag gaatagaccc aatattatgt gttggagaaa
    16561 ctttagaaca aagagaagct ggaaaaacta aagatgtttg taaagttcaa gttgaaaaag
    16621 ctttagaaaa tgttcttaaa gatgatttag caaaagtagt tgttgcatat gagccaatct
    16681 gggctattgg aactggtaaa actgcaactg ctgaagatgc taatgacgtt atatcttata
    16741 taagagaagt tataaaagga ttatatggag aattagctaa tgaagttaga atacaatacg
    16801 gtggaagtgt taaaccttca aatgtagccg aaataatggg tcaaagtgat atagatggag
    16861 ctttagtagg tggagctagt ttagctagta atgattacct agaccttgtt aatttctaag
    16921 gagtgaaatg atgaaaaaac cagttgcttt aattattatg gacgggtttg gatacaataa
    16981 ggatgttaag ggaaatgcaa ttgctgagtc caaaactcct aatttagata gaataaaaaa
    17041 agagtatcca aacacattga taaatgctag tggtcttgat gttggtctac ctgatggtca
    17101 aatgggaaat tcagaagttg gacacactaa cataggtgca ggtagaatag tatatcaaga
    17161 tttaactaga ataacaaaat ctataaaaga tggtgacttt tttactaata aagttttatg
    17221 tgaagcaatg gataatgcaa aagaaaactc tcttcatgta atgggacttt tgtctgatgg
    17281 aggagtacat tcacatatag accatcttaa ggctataatc aaaatggcaa aagataaagg
    17341 cgtacaaaag gtgtatgttc acgcatttac tgatggtaga gatactgacc ctcaaagtgc
    17401 attagaatat gccaaagaag tacaagctag tatggatgaa attggagtag gtgaatttgc
    17461 tacagtttct ggtagatact acgctatgga tagagataag agatgggaaa gagtagaact
    17521 tgcatacaat gccatggtta gaggtattgg tgaaaaagca aattctattg aggaagctat
    17581 tcaaaactct tatgatgatg gaaaaaatga tgagtttata atgccaacag ttattatgaa
    17641 agatgataaa ccagttggaa gtataaagga aaatgattca attatattct tcaactttag
    17701 accagataga gctagacaaa taactagagc tttagtttgt gaagagtttg atggatttaa
    17761 aagagaagat attaaaaact tctttgtatg cttaacagag tacgatataa ctatagagaa
    17821 tgtgcatata gcatttggac ctcaatcttt agccaacact ctaggtgagt atctagctaa
    17881 aaatggaaaa actcaactta gagctgctga aactgaaaag tatgcacatg taactttctt
    17941 cttcaatggt ggagtagaag agccaaataa aggtgaagaa agactattga taccttctcc
    18001 aaaggttgca acttatgatt taaaaccaga aatgtcagca tatgaattga cagataaagc
    18061 tttagataaa ttaggagaag ataagtttga ctttatagta ttaaactttg caaatcctga
    18121 tatggtaggt cacacaggaa gtatagaagc ggctataaag gctgttgaaa ctgtagatac
    18181 ttgtgtagga agattgatag ataaaatagt agagttaggt ggaagtgcaa taataactgc
    18241 tgaccacgga aatgctgaat atatgttaga cccagaaaca ggaaaaactg taacggctca
    18301 ctctattaat ccagtaccat ttattgtagt tggtcaagaa tatgaaagtg caaaattatt
    18361 ggatggagga agattatctg atatagcacc tactatttta gatatgatga agttagaaaa
    18421 gccagaagaa atgactggtc attcacttat ttcaaaatag tcgattctga taagtagata
    18481 ataatatata aactacaata taaatttaaa aataatgcag tttaggttta ttttgtaaag
    18541 tttagacttt atgacataag gtttaaattt tgtaagttct ggatattgta aggtgtagat
    18601 gaagatatat tttataaaat ttacaagata gacaatttat aaaataaaaa attacaatat
    18661 agataataat gtaaataatg atataaataa taacaagata gacaataaca atataaataa
    18721 taataattaa tatatattat ataagcaaaa attttagaat cattagttgt acattttatg
    18781 tttaatgttt taaatctagt tataatattt gtgtatttaa gattggtttt ggattttaga
    18841 caagtttttt tatattatat aaattaaaat attataaaaa ataaaataaa aataggaact
    18901 tttacaaatt tacccatcaa ataaatttgt acctaatttt caaaagcaac tttatgtact
    18961 ataatataga aagtagatta aaatagtaga cggatgttta cagtaaatga aaatttaact
    19021 aatagaaaat cgaagggaga tatacaaatg tcagttattg aattagtata tgctagagaa
    19081 gtattagact caagaggaaa tccaactgta gaagttgaag tagtattaga agatggagca
    19141 atgggaagag caatagttcc atcaggagca tctacaggag cttttgaagc tgttgaatta
    19201 agagatggag ataagggaag atacttagga aaaggtgtag aaacagctgt tgctaacgta
    19261 aatgaaataa tagcacctga aatagaagga atggatgcat ttgaccaacc agctatagat
    19321 gcaatcatga tagaattaga tggaactcca aacaaaggta aattaggagc taatgctata
    19381 ttaggtgttt caatggcagt agctagagca gctgctgatg aaataggttt accattattc
    19441 caatacctag gtggagtaaa tgctaaacaa ttacctgttc caatgatgaa catattaaac
    19501 ggtggagagc atgctgataa caacgttgat gttcaagaat ttatgatatt accagtagga
    19561 gcttgttgtt tcaaagaagg tttaagaatg ggagcagaag tattccattc gttaaagaaa
    19621 gttttaggag aaaaaggatt agcttgtggt gtaggtgacg aaggtggatt tgctccaaac
    19681 ttaggttcaa acagagaagc tttagaatta atagttgaag ctataacaaa agctggatat
    19741 aagccaggtg aagacgttat gttaggtctt gacgttgctg ctacagaaat gtacaacaaa
    19801 gaaactaaaa aatacgtttt agcaggagaa ggaaaagagt taactgctgc tgaaatggtt
    19861 gctttatatg aagattggtc aaacaacttc ccaataataa ctatagaaga tggtttagac
    19921 gaagaagatt gggatggatg gaaattatta actgaaaaat taggaaataa attacaatta
    19981 gttggtgacg acttatttgt tactaacaca gagagattag aaaaaggaat tgaaaatgga
    20041 gtagctaact ctatattagt taaagttaat caaataggta caataactga aactttagat
    20101 gctatagaaa tggctaagag agcaggatat actgctgtta tatctcacag atcaggagaa
    20161 actgaagatt ctactatagc agatttagct gttgcagtaa atgctggtca aataaaaact
    20221 ggtgctccat caagaactga tagagttgct aagtacaacc aattattaag aatagaagaa
    20281 atggttggag agcaagctag atattgtgga ttaaaatctt tctataactt aaaaaaatag
    20341 ttattaaaat ggttactaaa aaagattaat gaagagagaa tataagatat ttaagctcat
    20401 cttataagat ataaaagaga taagtgttaa ttgatttttc aattcactta tcctttttta
    20461 tattttatta cttaatttta ttcatagatt cagaaaaaat atgaataaat gtttctatct
    20521 catttttatc taattgcata ggaggttttt attaaaaaat aaaagtgaag acatattttg
    20581 atttaatcat aattgtcatt gaagtattat tgctaaatgt ggattattta ttttaaatta
    20641 tgttgaaatt aaaagttata tcaatatttt aaaatgattg ttttattttg gtggctattt
    20701 ataatatata caatgagagt agattatttt aagtgttaat ttatgtatta atttaaatag
    20761 ttttctcttc taagttttat tcatttttat attgagaata tagtaatata ttatagtaac
    20821 aatatatttt tttgtatgtt atttatagca taatagtctt gaaatggcta tattattgtg
    20881 atacactaaa gagtaatgaa atttaagtaa taaacagata ggaggggcaa gaatgagcaa
    20941 cattttaatg ggtgtgcaag tagtactagg gattttacta gtaattagca taatgcctca
    21001 agattctaag aatgctttac cttcagaatt tggtggagaa ggaagtcaag cttactttaa
    21061 accaaaagga aaacaagcat ttcttgctag agttacaaag ataacagcag tattattttt
    21121 tataaatgca ttggcattac ttatagttaa gaagtagtga tattgttgaa taactggcca
    21181 ttatttaatt agtgcatttg ctagacattt aaaaattaaa tttagttttt aataaaagta
    21241 catcaacata aaaagtacgt aaaataaaag ctggactaat gattttatat gattagtcca
    21301 gtttttattt tatagattga ctatttggtg gcgtttatta tttgtattta tatattgttt
    21361 gtatttatat attttcttca aactaaaaaa tatatagcaa cactactttc accatgttta
    21421 atgagataat atacacaaag ttatattata tagtaaaaat agtataataa tatgttttta
    21481 cgcgattaaa tcagttttat atatgtttct tataatacca atttgtgtta tcaaatatca
    21541 ttaaataaga ttattctgct ttaaaataaa tattattaaa aatactgtaa ttatagaaaa
    21601 tccagaagta aatactacaa tttgtccagc taattcactg tcagaatcca tctgttgtgc
    21661 cattgtaaat gaagaaactg cagttggagc agataacatt atcataagtg aagctaattc
    21721 tacatttcta aatccaagaa aaatgctaat tggtaaaaat atagcaggta caagtataag
    21781 ttttccacat acgcccaata taatgggttt tatatgcccc tttatagcag aaaaactaaa
    21841 agagccgcct agaattataa gtgataaagg agtagctatt ttagaaatat caccaatagt
    21901 tttgtgtaaa aatgtaggta tattaatatt taaaattagc attgtcaatc ctataaaaga
    21961 ggcgattatg agtggatttg ttaagacgct tttaatcata tgttttatat ttactttgcc
    22021 acctctaaaa atttcaagaa ttacaacaga taatacatta aacataggta caataactgc
    22081 aattaataaa gatgtgactc caatactctt atcgccaaat agtgaaattg tcacaggaat
    22141 accaaatata acgaaattgc tacgaaatac accttgtatt aatgcacccc ttgtcttatt
    22201 atctttttca attttaggaa taataaagac taagattaag aagattgaaa aaataattat
    22261 aacagctaca gccataagct taaaattaag agaaccatct aaatctgtat tgtatatatt
    22321 aaaaaataat aataatggca agaaagactt gaagcaaaca ttattcattt tatttaaagt
    22381 atgagtatca aatagaccta atttttttag aacatatcca agtgacattg tgagaaacaa
    22441 aggaagaaca acatttattg ataggattaa attttccaag gtttactctc cgtgattcta
    22501 tgatttgata attcaattaa atttccatta gtttttttca aataaataga tttcatatta
    22561 ccaaagacac ctgtacattc tacaattcct ctcttaattt gaatctcatt ttgttctaag
    22621 tatttttttg gctcatcaat atttgtgttt attttaaaac ataagttatc tctacttgct
    22681 tttgaatttt taacataagg taaaaattta taacctttta tgttaagatt tatcttaaca
    22741 tttctagcat taagtttata atttttgctc atttctttag atgaaaaacc aaatttttta
    22801 taaaaattga tataattttc tatattatta ttagtaatga ccacatgttc tatttttttt
    22861 atcatggcaa ctccttaaga ttttatataa attagttaaa tttatataag ttattaaatt
    22921 ttatatagat tgatgatatt tatataaatt att
//
LOCUS       DAYAOO010000066        22828 bp    DNA     linear   BCT 12-OCT-2024
DEFINITION  TPA_asm: Clostridioides difficile isolate ST8-SSI-h139-18
            SAMN40601845-rid21577343.denovo.066, whole genome shotgun sequence.
ACCESSION   DAYAOO010000066 DAYAOO010000000
VERSION     DAYAOO010000066.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN40601845
            Sequence Read Archive: SRR28438827
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 22828)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 22828)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-MAY-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-MAY-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002157583.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002157583.1
            Genome Coverage       :: 163x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/11/2024 16:19:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 4,038
            CDSs (total)                      :: 3,963
            Genes (coding)                    :: 3,930
            CDSs (with protein)               :: 3,930
            Genes (RNA)                       :: 75
            rRNAs                             :: 6, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 60
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 33
            CDSs (without protein)            :: 33
            Pseudo Genes (ambiguous residues) :: 0 of 33
            Pseudo Genes (frameshifted)       :: 7 of 33
            Pseudo Genes (incomplete)         :: 25 of 33
            Pseudo Genes (internal stop)      :: 11 of 33
            Pseudo Genes (multiple problems)  :: 8 of 33
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..22828
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN40601845-rid21577343.denovo.066"
                     /isolate="ST8-SSI-h139-18"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Denmark"
                     /collection_date="2018"
                     /collected_by="Statens Serum Institute"
     gene            225..689
                     /locus_tag="ACGI5H_002724"
     CDS             225..689
                     /locus_tag="ACGI5H_002724"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425587.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CtsR family transcriptional regulator"
                     /protein_id="HFG9698421.1"
                     /translation="MATMTDIIEKFIKDLMEEDNSIQIQRNELANLFSCAPSQINYVL
                     TTRFTIDRGYYIESKKGGGGYVQIEKIRKSKDGHIRELLNEKIGSQISYKKAKELLEG
                     LKESDLINERELKLILYAIDDKSLCMPIYELKEKVRSNILKNIIIGLFSIEE"
     gene            696..1190
                     /locus_tag="ACGI5H_002725"
     CDS             696..1190
                     /locus_tag="ACGI5H_002725"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421255.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005515 - protein binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="UvrB/UvrC motif-containing protein"
                     /protein_id="HFG9698422.1"
                     /translation="MLCQKCNKNKASVYYNKIVNGEKTEMYLCSECAKENTEMNFNLD
                     MPFSMMDIFSNLGFQPKKELEEKLVCPKCNTTYSEFKNNGRFGCSECYNAFSSQVNPM
                     LQNIHGHIEHTGKAPKKSFYKISVENEIKELKEDLDRAIKNEEYELAAQFRDKIKYLK
                     GSID"
     gene            1206..2231
                     /locus_tag="ACGI5H_002726"
     CDS             1206..2231
                     /locus_tag="ACGI5H_002726"
                     /EC_number="2.7.14.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421251.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016301 - kinase activity [Evidence IEA];
                     GO_process: GO:0046314 - phosphocreatine biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="protein arginine kinase"
                     /protein_id="HFG9698423.1"
                     /translation="MKENIVMKSRVRLARNLNNYPFPNKLDKECAMEIIEKVKNAFIN
                     SNLEQKEEFDFYKIEDLDQSKKMLMVEEHIISPDLAENDKSAVIVKKDKTISIMINEE
                     DHIRIQTICDDLNLEYAYSVANEIDDLLESSLEYAFNTKLGYLTSCPTNTGTGMRASV
                     MMHLPALSQLGYMDELYKISSQIGIAIRGIYGERTEALGNIYQISNQLTLGRTESNII
                     ENVSGLTKDAISKEIKAREILQKKLGIKLEDKIFRSIGTLENSRVMSSAEAMSHLSNI
                     KMGIEMNYIDKLDLRAIEQLMIGIQPAHQSIMYKSDDVENRDINRATYIRETLEKLRG
                     GMNCELQ"
     gene            2218..4665
                     /locus_tag="ACGI5H_002727"
     CDS             2218..4665
                     /locus_tag="ACGI5H_002727"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421249.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp protease ATP-binding subunit"
                     /protein_id="HFG9698424.1"
                     /translation="MNFNRFTQRAKKAIDLAFESAKSLGHNIVGSEHILLGLLREEEG
                     IAAKVLSKVGFTEAYLEGKIVDMEGKGEEISEDIVLSPRSKQILELSGMFANKLKTNY
                     IGTEHILLAIIQEGEGIANKILNYAGVNDRTLAQLTIDMMGISDKNQYKAENSYTGNQ
                     NQAESKVLDKYGRNLTLYAKQNKIDPVIGREKEIQRVIQILSRRTKNNPVLIGDPGVG
                     KTAIAEGLATNIALGNVPETLKNKTLYSLEMGSLLAGAKYRGEFEERIKEVVDEVVKN
                     GNIILFIDEMHTIIGAGSTGEGSIDASNILKPALARGEIQVIGATTIDEYRKHVEKDS
                     ALERRFQPVMVDEPTKEDSIKILEGLRDKYEAHHKVKITDDAIKAAVELSTRYISDRY
                     LPDKAIDLIDEAASKVRLKENTPPSEIKKLELEIENIDKEKEEAVRCQDFEKAAKIRD
                     EQGLLKKQLEDVRERWNKSSKHSDLVDGEVIAEVVGLWTGIPVNKILEEEADRLLRLE
                     EILHNKVIGQEQAVKSISKAIRRSRAGLKDPNRPIGSFLFLGPTGVGKTELSKALAEV
                     QFGDENQIIRIDMSEYMEKHAVSRMIGSPPGYVGHDEGGQLTEKVRRNPYSVILFDEI
                     EKAHPDVFNILLQILDDGRLTDSKGRTVDFKNTIVIMTSNVGASTIGRQKTLGFSIAK
                     GDEEEKSQYEKMKENIMGELKQRFRPEFLNRIDDIIVFHSLNENHISKIVLLMAAKLQ
                     ERLKEMDIKLEMSDEAVKLISKSGFDLEYGARPLKRALQKELEDELSEAILKGNVKKG
                     SNVVAKVKDEKIVFETK"
     gene            4845..6218
                     /gene="radA"
                     /locus_tag="ACGI5H_002728"
     CDS             4845..6218
                     /gene="radA"
                     /locus_tag="ACGI5H_002728"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421247.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003684 - damaged DNA binding [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RadA"
                     /protein_id="HFG9698425.1"
                     /translation="MAKIKTKYVCQSCGYETAKWLGKCPECTKWNTFVEEIDQKSTKK
                     EVFIIDKSSSKPVSINSIESKEEERFTTDINELDRVLGGGIVKGSLVLVGGDPGIGKS
                     TLLIQVSSNVANLGKTVLYITGEESESQIKMRAKRLGINSEKLYIFAENNLSIIESYL
                     ESVNPELIILDSIQTVFSPEISSAPGTVSQIKEGTSKFMKISKKMGISTFIVGHVTKE
                     GSLAGPKLLEHMVDTVLYFEGERYNTYRLVRAVKNRFGSTNELGVFEMRDLGLVELDN
                     PSKILISEKPKDVAGSVIISTVEGTRPMLLELQALVSPTSFGIPKRTSTGVDYNRVGM
                     LLAVLEKRVGLQIQNQDVYINIVGGIKINEPSIDLGIAISVASSFRNIPIDEDIAVTG
                     EVGLTGEVRAVSFIEKRIAECKKLGFKKIVVPRSNYDVVKETKGIEIWPVDNLRQAIN
                     IVLGRNQ"
     gene            6221..7291
                     /gene="disA"
                     /locus_tag="ACGI5H_002729"
     CDS             6221..7291
                     /gene="disA"
                     /locus_tag="ACGI5H_002729"
                     /EC_number="2.7.7.85"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004453975.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA integrity scanning diadenylate cyclase DisA"
                     /protein_id="HFG9698426.1"
                     /translation="MENFLDNKNMLYALKMISPGTPLRLGLNNVLRAKTGGLIVIATN
                     EDVMKIVDGGFAINAEYSPSYLYELAKMDGAIVLSGDVKKILFANAQLIPDYFIETSE
                     TGTRHRTAERVAKQTGAIVIGISQRRNVITVYRGNEKYVVEDISKIFTKANQAIQTLE
                     KYKTVLDQAVTNLNALEFNDLVTIYDVALVMQKMEMVMRVTSIIEKYVIELGDEGTLV
                     SMQLEELMGTTRIDQKLIFKDYNKENTEIKELMKKVKNLNSEELIELVNMAKLLGYSG
                     FSESMDMPIKTRGYRILSKIHRLPTAIIENLVNYFENFQQILDASIEELDEVEGIGEI
                     RATYIKNGLIKMKQLVLLDRHI"
     gene            7380..8474
                     /locus_tag="ACGI5H_002730"
     CDS             7380..8474
                     /locus_tag="ACGI5H_002730"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421243.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PIN/TRAM domain-containing protein"
                     /protein_id="HFG9698427.1"
                     /translation="MIRKVTRILFILLGFTIGITTYLTLMKDFEILTFGKETYGYIAA
                     VVAGIIIAILGYLIEPWVVNKVKEIAKIVDKELSKYPQTDILLGSMGLIVGFVIAYLL
                     SGLVNRIPIVGGILSLLLYLFLGYLGMKVALKSKNDLFNIGKLGRLANPIKDKDKDKE
                     NKKEVKAIPPKVLDTSVIIDGRIADICKTGFIEGKLIIPAFVLEELRHIADSSDDLKR
                     VRGRRGLDILNIIQKELNIEVEISERDFDDIAEVDSKLLKLAQVLNGKVVTNDYNLNK
                     VAQFQGVEVLNINELANAIKPVAIPGEDMVVQVVKEGKEAQQGVAYLDDGTMIVVDGG
                     RKYMNETIKVLVTSVLQTPAGRMIFAKPKN"
     gene            8603..10780
                     /locus_tag="ACGI5H_002731"
     CDS             8603..10780
                     /locus_tag="ACGI5H_002731"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860624.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9698428.1"
                     /translation="MRKKIISFLATFIIILTSASQYSFADDISTRGKVIFIDMNRTSM
                     SNMLRIKSLREELDNRGYIGLMNIRGDKGSDDRRSYASMGAGGRANVANEEDINFESS
                     SKDRNIVFESATGKSAKGINNLTINKSINENLNFGEYGSVLGSLGQSLSDNGLKASVL
                     GNSDIIENGQLIKNRNLCLTAMDEYGRIPNGNVDTINKKDLSMPYGISTDYDKLIVET
                     KEAYKNNDVIFVELGDTYRLDLYKPNLNEKTYESMKDNIEKNIDIYLKNIFSMVEEND
                     TVYIASAFPSDLDYKNKRRLSPIIKLNGEGKGILSSSTTRREGIVTNLDVGVEILDNF
                     NIKNQNMVGRKYELINRDDNKEFLMDEYQKIVSISSIRSTILNGFVSIVFLSWIVAMI
                     AILFRKHISKNYKETTFFILKELLKIGIVMPLSFMITPIMNFKTPLAISLGIIIITLT
                     IYLISKVLIKNDLKNMLFFTGLTIVIMVIDAGFGSYLMKSNVMSYDCIIGARYYGVGN
                     EYQGVAIGSAIFTFAILLTYKNIPKWSIIVFSLVILITSASPIMGANVGSAISECVAF
                     LLFILLIYNVKIDFKKIVLLGIAVVFVLGVFVAIDMILGSNSHLGMFVKEIYFNGPGE
                     IIQTFSRKIEMNLKLAQTSAWVNILLTGIGVILVLMINQIRYFKQLMDEYPIVFKGFI
                     ASIAGCLVTLLVNDSGIVSSATAFIYVIVPMITLSINLTALKE"
     gene            complement(10960..11811)
                     /locus_tag="ACGI5H_002732"
     CDS             complement(10960..11811)
                     /locus_tag="ACGI5H_002732"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421239.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_function: GO:0043565 - sequence-specific DNA binding
                     [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HFG9698429.1"
                     /translation="MNRNNFSHEIIEPIDNLDVNFKLFDDSGSYVANHWHNSLEIIYI
                     TSGDLQINMEGYTYNLKANECMFINSGIIHSTRCIYQNTSILLQVPLSFLNKYIPDFK
                     NCYFDFKVNANDNNYKKNSSKVKLILENMREIKLSSPPAANLLFTSLLFELLFELYTN
                     FKISVGNKNMKKTVLDLSKFEPVLEYTKINYKMPISINKIAKVAHLQPEYFCRKFKQY
                     MGQTYLEYLNDVRISHIYKDLINTNDTLCSILEAHGFTNTKLFYRIFKEKFKCTPKHI
                     RKNLPKI"
     gene            12028..13194
                     /locus_tag="ACGI5H_002733"
     CDS             12028..13194
                     /locus_tag="ACGI5H_002733"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009887803.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004553 - hydrolase activity, hydrolyzing
                     O-glycosyl compounds [Evidence IEA];
                     GO_process: GO:0000272 - polysaccharide catabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cellulase family glycosylhydrolase"
                     /protein_id="HFG9698430.1"
                     /translation="MYIKGVNLGGWLVLEKWMTSSLFEGTEAEDEYYLPRQLSREAYE
                     SRIKTHRSEYITERDFAMIKSMGFNSVRIPVPYFIFGDCEPFIGCVKELDKAFAWADK
                     YGLSILIDLHTVPGSQNGFDNGGISGICSWSQNPEYVAFTLNVLERLAKRYGMRHELY
                     GIQILNEPITERMWNIMNVPNRFKAVDKEMARGSKPNSLEFLRDFYIKAYKVMRPYMR
                     EENVIVFHDAFELKAWKDFMREEEFKNVVLDTHQYLMLAEADGCEQSIDSYLKYIREN
                     YAKDILQMQKYFPVICGEWSLFNSYACGIDTNGGQSPLNGIESNIDKLSKDDKRELYR
                     KIAKAQLDAWRNGSGHYYWNYKLLLDTVNEEGWIGWDSWDLVKCVAQEWYPIEY"
     gene            13216..14862
                     /locus_tag="ACGI5H_002734"
     CDS             13216..14862
                     /locus_tag="ACGI5H_002734"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004453968.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 43 protein"
                     /protein_id="HFG9698431.1"
                     /translation="MIKNPILPGFNPDPCICRKGDDYYLVVSSFEWFPGIPVYHSKDL
                     KNWELYTHILTDETKIDLKKLPSSKGIWAPCLTYCEEEDLFYIVYGIMNSMNARYFDV
                     DNYLITSKDIKGEWSEPVYLHSSGFDASIFHDDDGKKWIASLDWETREGYEKPGVICL
                     VEYCTKKKEIVGYPKRIWSGGTDRGCIEAPHITKRGDYYYIMCAEGGTGYGHSVTMGR
                     AKNIWGPYEKDSMNPIVTSIPGDFYERHDPDHLKPKYYNPESKLQKSGHGSYIETTSG
                     EVYLVHLTSRPFVPELRCTLGRETAIQKMKWTKDNWLRMEDESNLAKEYVSESKLEEH
                     LVSSIPSFDDFDSNELGLQYYAPRISPLSFADVKSRPGYVRIRGQESRTSLNKVSILA
                     RKLTSVYARITTKMEFYPEVHQHSAGLIMYYDNMNYINLRKYYSETLGQSALSIIHLE
                     NGEKTEFLNTRIPIKDIPIYLRLYVQGRKSYFEWSYDEKNYQRIGKVFDTTKFSDEYC
                     KYGEFTGTFIGLTCADRVKHKHYADFDFFEYIVDESKDVD"
     gene            14959..16332
                     /locus_tag="ACGI5H_002735"
     CDS             14959..16332
                     /locus_tag="ACGI5H_002735"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729261.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HFG9698432.1"
                     /translation="MNTEVNVKATTIRYEKISFFERISYGCGDLGCNIIYSAMSAFLL
                     FYYTNYADVSAAAVGSIMLVSRILDGFSDLTMGIIVDRTKSKYGKARPWILRMAIPFA
                     IAAVLLFSVPSNLGITSKLIYIFITYNLVSTVIYTAINVPYATLNSLITQNQYERGVL
                     SIFRMILATCGTLLINGLTLPLVEYFGNNLSAWTKTFFVFGIASIMVFFITFTGTKER
                     VKAVKQDRNEVIPFKIGIKSLFRNKYWIQITLCLVCIFIVFAINGGSSVYYAKFILGD
                     EKLFGPINMVSNISQIIAMFMVAPFIKKFGKRNVLIVGSIILISSNVMFIIVGQNHIG
                     VIFASAIKGIGSAGIASTMFAIVSDTIEYGEWKTGYRTEGLINSASSFGFKVGNGLGS
                     AILGAVLSIGGYVGTSATQSDLAIVSIKVCFIYLPIFITILQIIIMSFYKLDKEYSTI
                     LNELNTK"
     gene            16777..17730
                     /locus_tag="ACGI5H_002736"
     CDS             16777..17730
                     /locus_tag="ACGI5H_002736"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009904745.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0030246 - carbohydrate binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sugar-binding transcriptional regulator"
                     /protein_id="HFG9698433.1"
                     /translation="MKKIGDLRLMMKCCSLYYEDNLNQQEIANQLGISRPTISRILKE
                     AFEQGIVKIQIVDVLKNDYQKIERSLERKYKLKEVIVVDDKQDALTQKQELARAVSEY
                     LTRVVKENDIIGVSIGTTLKEIPRYVEKSNCKNVTFIPLLGGIGDNEIDIHANQIAVS
                     LARAFGGDFKLLHAPAVMSDLSTKEKLCKDEKIKEVLDLIDKTTIAIVGIGNPMSLNS
                     TIMASGYMNEADIEDLKKYNSIGAICLQAFDKEGKTSILEFNQRVLGVKLEDLKKIKR
                     TIGVASGDEKIEAIKASLKAKFINSLAINHSLALKLLEDCD"
     gene            17768..18730
                     /locus_tag="ACGI5H_002737"
     CDS             17768..18730
                     /locus_tag="ACGI5H_002737"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009887810.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiamine pyrophosphate-dependent dehydrogenase
                     E1 component subunit alpha"
                     /protein_id="HFG9698434.1"
                     /translation="MSISKETLLEMYKRMNQARKFEEKVSWFFARGMVHGTTHLSVGQ
                     EASSVAAVMALEKGDLVSLTHRGHSQFIGMGIDLNKMMAELMGKETGFCKGKGGSMHI
                     ADIESGNLGANGVVGGGLTIAPGAALTQQYKKTGKIVLCSFGDGASNEGTFHEGINLS
                     SIWKLPIIFYCENNLYGMSTSIKRHMNIESIATRAASYGIEGISIDGYNPIEVYETVQ
                     KAAEKCRRGEGPVLIESRTYRWLGHSKSDANVYRTKEEIESWKAKDPIEFLKNYLIEN
                     NLSNEDELDKIQEFAKQSIEDAVEFAQNSPNPKIESLLEDVYAD"
     gene            18755..19741
                     /locus_tag="ACGI5H_002738"
     CDS             18755..19741
                     /locus_tag="ACGI5H_002738"
                     /EC_number="1.2.4.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425542.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-ketoacid dehydrogenase subunit beta"
                     /protein_id="HFG9698435.1"
                     /translation="MSTRELTYAQAIKEAMSEEMRRDENVIFMGEDIGIYGGAFGVSV
                     GMIDEFGPERVRDTPISEAAIAGAAAGAAATGLRPIMEVMFMDFVTISMDAIVNQAAK
                     MRYMFGGKAQVPMVVRCPGGSGTGSAEQHSQSLEAWFCHVPGVKVVAPSTPADAKGLL
                     KAAIRDNNPVIFVENKLLYRKKGFVPEDDYVIEIGKADIKREGTDVTVITYGRMLQSV
                     EEAAETLSKENINVEIIDLRTLYPLDKETIVKSVCKTGRVLICHEAAKTGGLGGEISA
                     LITESESFDYLDAPVKRICGKDVPIPYNPELEKAVVPRVDEIEEAIKSLIVR"
     gene            19754..20800
                     /locus_tag="ACGI5H_002739"
     CDS             19754..20800
                     /locus_tag="ACGI5H_002739"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895167.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016746 - acyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="2-oxo acid dehydrogenase subunit E2"
                     /protein_id="HFG9698436.1"
                     /translation="MVANKIKATPAARSQARKDNIKLDRLIGSGENGRIHLVDVLNYL
                     KDNKANTTPLARRIAEDLNIDLETIVGTGYNGKIRKCDVEKLTAKETIVSTNTSKSSE
                     KKELKIENENSSMFNTVEGIFEKPNPMRATVAKRMSESYFSAPVFTFNIEVDATELKV
                     LRAKLIDTVKESTGVKLTMTDLIVMAVSKILPNHQALNSAWTDEGIFRYKDVNIAIAV
                     GLDEGLYVPVVKNANKKSLKEIAKESKELAEKVKTGKLMPADQEGNTFTISNVGMYGI
                     TTFTPIINMPSSAILGVGATQDKFVPVNGEAKIKPIMNLSLTSDHRVIDGTVAAKFLK
                     DLKELLENPLSMLV"
     gene            20967..22697
                     /gene="lpdA"
                     /locus_tag="ACGI5H_002740"
     CDS             20967..22697
                     /gene="lpdA"
                     /locus_tag="ACGI5H_002740"
                     /EC_number="1.8.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860626.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004148 - dihydrolipoyl dehydrogenase
                     activity [Evidence IEA];
                     GO_function: GO:0050660 - flavin adenine dinucleotide
                     binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrolipoyl dehydrogenase"
                     /protein_id="HFG9698437.1"
                     /translation="MSVEVIMPKAGVAMEEGTIVSWLKQEGEEVKIGEPILEITTDKV
                     NMEIESEGEGTLAVIIHKEEGEVLPVFTVIGVIAEKGENQEEVKAKYLSGNVSKEDIV
                     EENQNIEFKEEKINKKECNHDYDVVVIGGGPGGYLSALKAALLGGRVALVEENILGGT
                     CLNRGCIPTKTYIKTAEILEEIDQLSKRGVKVTVDKEQDIKKAIKYKNRVVKKLTAGV
                     GGLLKSRDVDVFNLKASVKEEHKVILSDGKVLDTENIIIATGSKVRILPIKGIESNLI
                     ITSTEALDLETVPEELVIIGGGVIGCEFAEIFNSRGSKVTIVEMEDRVIPRMDKELSE
                     SLKYSLSKKGINVLTKKKVSEFKEEGNNILVCIEGEEPIKADLCLYAIGREANLSGIE
                     DLDIKIDKGSIVVNSKMETSIPSIYAVGDVTGGVMLAHAAFKMGEVAASNALGVNKEV
                     DLGALPSCVYTIPEVASVGITEEDARKKYNVKVGKFNFAGNGRALASGQEQGYVKVVA
                     DAKYGEILGIHMFGCGVAELINHAASFKALEIPTDEASELIFGHPCTSEALMEALADV
                     NGECLHLPKK"
BASE COUNT         9253 a         2382 c         4319 g         6874 t
ORIGIN      
        1 taaagtattt aaagttctga aatctaatca tgaagcaaaa aattagcatt tggttatcaa
       61 taaatataat aaataaaaac tcataattaa tgaaagaata aattcatatc taaatttcta
      121 taaaaaattt aaatttatac aatttagggc tttaaaaatt taaataatag gtgtaaaata
      181 atagtcaaag aaagtcaaaa ataaaaaggt gtgtggtgat attaatggca actatgacag
      241 atataattga aaaatttatt aaagatttga tggaagaaga taatagcata caaattcaaa
      301 gaaatgaact agcaaacttg tttagttgtg caccatcaca aataaattat gtcttaacaa
      361 caagatttac aatagataga ggatattaca ttgaaagtaa aaaaggtggc ggaggatatg
      421 ttcaaataga aaaaatacga aaaagtaaag atgggcatat tagagaacta ctaaatgaaa
      481 aaataggaag tcagatatcc tataaaaaag caaaagaatt attagaaggt ttaaaagagt
      541 cggatttgat taacgaaaga gaattaaaat taatattata tgcaatagat gataaatcat
      601 tgtgtatgcc aatatatgaa ttaaaagaga aggtaaggtc taatatttta aagaatataa
      661 taataggatt atttagtata gaggagtgat aatttatgct atgtcaaaaa tgcaataaga
      721 ataaagcatc tgtatattat aataagatag tcaatggaga aaaaacagag atgtatttat
      781 gtagtgagtg tgcaaaagag aatacagaaa tgaattttaa cttagatatg cctttttcaa
      841 tgatggatat attttctaat ttaggttttc aacctaaaaa agaacttgag gaaaagctag
      901 tttgtcctaa atgcaataca acatatagtg agtttaagaa taatgggaga tttggatgta
      961 gtgaatgtta taatgcattt agtagtcaag taaatccaat gcttcaaaat atacatgggc
     1021 atatagaaca tacaggaaaa gcacctaaaa aatcttttta taagataagt gtagaaaatg
     1081 agattaaaga actaaaagaa gatttagata gagctataaa aaatgaagag tatgagttag
     1141 cagctcaatt tagagataaa attaaatatt taaaaggttc tattgactaa gattggagtg
     1201 atattatgaa agagaacata gtcatgaaat caagagttag gctagctaga aatttaaata
     1261 actatccatt tccaaataaa ttagataaag aatgtgccat ggaaataata gaaaaagtaa
     1321 aaaatgcgtt tattaattct aacttagaac aaaaagaaga atttgatttc tataaaattg
     1381 aagatttaga ccaatctaaa aaaatgctta tggttgaaga acatataata agcccagatt
     1441 tagcagaaaa tgataaaagt gcagttatag taaaaaaaga taaaactata agtataatga
     1501 taaatgaaga agaccatata aggatacaaa ctatatgtga tgatttaaac ttagaatatg
     1561 catatagtgt agcaaatgaa atagatgatt tgttagaatc aagtttagaa tatgccttta
     1621 acacaaagct aggttatcta acatcttgtc caactaatac aggaacagga atgagagctt
     1681 ctgtaatgat gcatttacca gcattaagtc aactaggcta tatggatgaa ctttataaaa
     1741 tttcatcaca aataggtata gcaattagag ggatatatgg agaacgaaca gaagcgttgg
     1801 gaaatatata tcaaatatct aatcaactta cacttggaag aacagagtct aatattatag
     1861 aaaatgtaag tggacttaca aaagatgcaa tttcaaaaga aataaaagct agagaaatat
     1921 tgcaaaaaaa attaggtata aaactagaag ataaaatatt tagatcgata gggacacttg
     1981 aaaattcaag agtaatgagt agcgcagagg caatgagcca tctatcaaat ataaaaatgg
     2041 gaatagaaat gaactatata gataaactag atttaagggc tatagaacaa cttatgatag
     2101 gtatacaacc agcgcatcag tcaataatgt ataagagtga tgatgttgag aatagagata
     2161 taaatagagc aacatatatt agagaaactt tggaaaaatt aagaggaggg atgaattgtg
     2221 aacttcaata gatttacaca aagagctaaa aaggcaattg atttagcgtt tgaatctgct
     2281 aaaagtctag gacacaatat tgtcggaagt gaacatatac ttttaggtct tttaagagaa
     2341 gaagaaggta tagctgctaa agttctaagt aaagttggat ttacagaagc ttatttagaa
     2401 ggcaaaatag ttgatatgga aggtaaggga gaagaaatct cagaagatat agtattaagt
     2461 ccaaggagta aacaaatact tgaattatca ggaatgtttg caaataaatt aaaaacaaat
     2521 tatattggga ctgagcatat attattagca attattcaag aaggtgaagg aatagctaat
     2581 aagattttaa attatgctgg agtaaatgat aggactttag cccaattaac aattgatatg
     2641 atgggtatta gtgataaaaa tcaatacaaa gcagagaata gttacacggg caaccagaat
     2701 caagcagaat ctaaagtact tgataagtat ggaagaaatc ttacactata tgcaaaacag
     2761 aataaaatag accctgtaat aggtagagaa aaagaaatac aaagagtaat acaaatatta
     2821 agtagaagaa ctaaaaacaa tccagtgttg ataggagacc caggtgtagg gaaaacagcc
     2881 atagctgaag gtctggctac aaatatagcc ttaggaaatg ttccagaaac actaaaaaac
     2941 aaaactttat actctttaga gatgggttca ttattggctg gagctaagta tagaggagaa
     3001 tttgaagaaa gaattaaaga agttgtagat gaagttgtta aaaatggaaa cataatctta
     3061 tttatagatg agatgcacac aataataggg gctgggtcta ctggagaagg ctctatagat
     3121 gcttcaaata tattaaagcc agccttagca agaggagaaa tacaagttat aggtgcaact
     3181 acaattgatg aatatagaaa gcatgttgaa aaagattctg ctctagaaag aagattccaa
     3241 ccagttatgg tagatgaacc aactaaagag gactcaataa aaatattaga aggattaaga
     3301 gataaatatg aagctcatca taaagttaaa ataactgatg atgctataaa ggcagctgta
     3361 gaattatcaa ctagatatat atcagacaga tatctgccag ataaagctat agacttgatt
     3421 gatgaagctg catcaaaagt aagattaaaa gaaaatacac ctccttcaga aataaaaaaa
     3481 ttagaactag aaatagaaaa tatagataaa gaaaaagaag aagcagtaag atgtcaagac
     3541 tttgagaaag cagccaaaat aagagatgaa caaggtctac ttaaaaaaca attagaagat
     3601 gttagagaaa gatggaacaa gtcatctaaa cattcagatt tagttgatgg agaagttatt
     3661 gctgaagtag tgggcttatg gacaggaata ccagttaata aaattcttga agaagaggct
     3721 gatagacttt tgagacttga ggaaatactg cacaataaag ttataggtca agaacaagca
     3781 gtaaaatcta tttcaaaggc aatcagaagg tcaagagcag gtcttaaaga ccctaataga
     3841 ccaattggtt catttttatt tttaggtcca acaggagtag gtaaaacaga attatctaag
     3901 gcattagcag aagtgcaatt tggagatgaa aatcaaataa ttagaataga tatgtctgaa
     3961 tatatggaaa aacatgctgt gtcaagaatg ataggttcac ctccaggtta tgtaggtcat
     4021 gatgaaggtg gtcaattaac tgaaaaagta agaagaaatc catattcagt tatcttattt
     4081 gatgagatag aaaaagctca tccagatgta tttaatattc tgttacaaat tctagatgat
     4141 ggtagactaa ctgattcaaa aggaagaact gtagatttta agaatactat tgtaataatg
     4201 acatcaaatg ttggagcatc tacaattggt agacaaaaaa ctttaggatt tagtatagct
     4261 aaaggagacg aagaagaaaa atctcaatat gaaaaaatga aagaaaatat aatgggtgaa
     4321 ttaaaacaaa gattcagacc agagttttta aacagaatag atgatataat tgttttccac
     4381 tcactaaatg aaaatcatat atcaaaaata gtacttttaa tggcagcgaa actacaagag
     4441 agattaaaag aaatggatat aaaattagaa atgagtgatg aggctgttaa attaatttct
     4501 aaatctggat ttgacttaga atatggagca agacctctta aaagagcttt acaaaaagag
     4561 ttggaagatg agctatctga agcaatctta aaaggtaatg tgaaaaaggg aagtaatgta
     4621 gtagcaaaag tcaaagatga aaaaatagtt tttgaaacta aataatttaa tagagttgca
     4681 ttttaaaata ttgcaaatat aagttttata atctaaacaa aattttaagg gcaatgaatc
     4741 tataataatt cattgtcctt aattatttta tttaatcttt acatattgtc tttcagatat
     4801 gctaaaatta tagtatagaa taaaaaatta aggatgataa aagtatggca aaaataaaaa
     4861 caaaatatgt atgtcaatct tgcggatatg aaacagctaa atggcttggt aaatgtccag
     4921 aatgtacaaa atggaataca tttgtagaag aaatagacca aaaaagcacc aaaaaagagg
     4981 tctttataat agataaatct tcatctaaac cagtcagtat aaactcaata gagagtaaag
     5041 aagaagagcg gtttacaaca gatataaatg aattagatag agtgcttgga ggaggtatag
     5101 ttaaaggctc tttagtgctt gttggtggtg accctggtat aggtaaatca acacttttaa
     5161 tccaagtatc tagtaatgtt gccaatttag gaaaaactgt tttatatata actggagaag
     5221 aatcagaatc tcaaataaaa atgagagcta aaagattagg tattaactca gaaaaattat
     5281 atatatttgc tgaaaataat ttaagtataa ttgaatctta tttagaaagt gtaaatccag
     5341 aattaataat tctagactca attcaaactg tcttcagtcc agaaatatcc tcggcaccag
     5401 gaactgtcag ccaaattaaa gaaggtactt caaaattcat gaaaatttct aaaaaaatgg
     5461 gaatttcaac gttcatagtt gggcatgtta caaaagaagg ttcactagca ggaccaaaat
     5521 tattagagca tatggttgat actgttctat attttgaagg agaaagatat aatacttata
     5581 gattagtaag agctgttaaa aatcgatttg gttcaactaa tgaacttgga gtatttgaaa
     5641 tgagggattt aggattagta gaacttgata atccatctaa aattttaatc tctgaaaaac
     5701 caaaagatgt agcaggttca gtaataatat ctactgtaga aggtacgagg ccaatgttac
     5761 ttgaattgca agcattagtt tctcctacaa gttttggtat accaaaaaga acatctacag
     5821 gagtcgatta caatagagta ggtatgttat tagcagtatt agaaaaacgt gttggtttgc
     5881 aaatacaaaa tcaagatgtc tatataaaca tagttggagg aataaagata aatgaaccct
     5941 caattgattt agggatagcc atttctgtag catctagttt tagaaatata ccgatagatg
     6001 aagatatagc tgttacagga gaagtgggac ttacaggaga agttagagca gtaagcttta
     6061 tagaaaagag aatagctgag tgtaaaaaac ttggatttaa aaagatagta gttcctagaa
     6121 gtaattatga tgttgtaaaa gagaccaaag gcatagaaat atggccagta gataacttaa
     6181 gacaagctat aaatatagta cttgggagga atcaataaat atggagaatt ttctagataa
     6241 taaaaatatg ctatatgcat taaaaatgat atctcctgga actccactta gattaggtct
     6301 aaacaatgta ctaagagcta agactggtgg attaattgta attgcaacaa acgaagatgt
     6361 aatgaaaata gtagatggag gatttgctat aaatgcagaa tattcaccat catatctata
     6421 tgaattagct aaaatggatg gagctatagt tttaagtggt gatgtaaaga aaatattatt
     6481 tgctaatgca caacttatac ctgactattt tatagaaaca tcagagacag gaacaagaca
     6541 tagaacagca gaaagagtag caaaacaaac tggtgctata gtcataggaa tttcacaaag
     6601 aagaaatgtt ataacagttt atagaggaaa tgagaagtat gtagtcgaag atatatctaa
     6661 gatatttact aaggcaaatc aggctataca aactctggaa aaatataaga cagtattgga
     6721 ccaagctgta acaaatttaa atgccttaga gtttaatgat ttggtaacta tttatgatgt
     6781 tgcattagtc atgcaaaaga tggaaatggt aatgagagtt acaagtataa ttgaaaaata
     6841 tgtgatagaa ttgggtgatg aaggaacttt agtaagtatg caattagaag aattaatggg
     6901 tacaaccaga atagaccaga aattaatatt caaagattat aataaagaaa acacagaaat
     6961 aaaagaactt atgaaaaagg tcaaaaattt aaattcagaa gaactaatag aattggtcaa
     7021 tatggcaaaa ctattagggt atagtggttt ttcagaaagt atggatatgc ctataaaaac
     7081 aagaggttat aggattctta gcaaaataca tagactacca acagcaataa tagaaaactt
     7141 agtaaattat tttgaaaact ttcaacaaat tttagatgca tctattgaag aattagatga
     7201 ggttgaagga ataggtgaaa taagagcaac atatataaaa aatggactca taaaaatgaa
     7261 acaattagtc ttattagata gacacatatg atgaatttta aatgaatttt actacttttt
     7321 tcttgaatat aatatacact ttggtctata atagataagt ataactaggg ggtgaagcat
     7381 tgataaggaa agtaacaaga atattgttta ttttacttgg atttacaata ggtataacaa
     7441 cctatttaac attaatgaaa gattttgaaa tattaacatt tggaaaagaa acatatggtt
     7501 atatcgcagc tgtagtagca ggtataataa tagccatttt aggatatctt atagagccat
     7561 gggttgtaaa taaagtaaaa gaaattgcta aaatagtgga taaagaattg tcaaaatatc
     7621 ctcagactga tatattgtta gggtctatgg gtcttatagt aggatttgtt attgcgtatt
     7681 tattaagtgg attagtaaat agaataccaa tagtaggtgg aatactatcc ttactattat
     7741 atttattcct aggatatctt ggaatgaaag ttgcgcttaa aagtaaaaat gatttattta
     7801 atattggaaa actaggaaga ttagcaaatc ctattaagga taaagataag gataaagaaa
     7861 ataaaaaaga agtaaaagcc attcctccaa aagtattaga tacaagtgta ataattgatg
     7921 gaagaatagc tgatatttgt aagactgggt ttatagaagg aaaacttatt attcctgctt
     7981 ttgttttgga ggaactaaga catattgcag attcttcaga tgatttaaaa agagtaagag
     8041 gtagaagagg tctggatata ttaaatataa ttcagaaaga attaaatata gaagttgaaa
     8101 taagtgagag agactttgat gatatagcag aagttgatag taaattatta aagcttgctc
     8161 aggttttaaa tggaaaagtt gttacaaatg attataactt aaataaagtt gctcaattcc
     8221 aaggtgttga agtattaaat ataaatgagt tagctaatgc tataaaacca gttgctatac
     8281 caggtgaaga tatggttgtt caagtggtta aagaaggaaa agaggctcaa caaggtgttg
     8341 catatctaga tgatggaact atgatagttg ttgatggagg aagaaaatat atgaatgaga
     8401 ctataaaagt actcgttact tctgttcttc aaactcctgc aggtagaatg atatttgcaa
     8461 aacctaaaaa ttaatatgtt caaagaaacc tataatttgg gctgtttatt ttaaatagat
     8521 ggtccaaatt tatttattta taacgataat gtttaatgta ttcttaaaga tggggattta
     8581 aatcagaaag cagggagaat ttatgagaaa aaagattata tctttcttag caacatttat
     8641 cataatatta acatcagcaa gtcagtatag ttttgcagat gatatatcaa cacgtggaaa
     8701 agtaatattt atagatatga atagaactag tatgagtaat atgttaagaa taaaatcatt
     8761 aagagaagaa ctagacaata gagggtatat tggcttgatg aatataagag gcgataaagg
     8821 aagtgatgat agaaggtcat atgctagtat gggtgctggt ggtagagcta atgtggctaa
     8881 tgaagaagat attaattttg aaagctcgag taaggataga aatatagttt ttgaatcagc
     8941 tacaggaaaa agtgcaaaag gtataaataa tttaactata aataagtcta taaatgaaaa
     9001 tttaaacttt ggagagtatg gttctgtatt agggtcatta ggacaaagtt tatctgataa
     9061 tggattaaaa gcatctgtat tgggtaattc agatataatt gaaaatggtc aacttataaa
     9121 aaatagaaac ttatgtctaa ctgcaatgga tgaatatgga agaataccta atggaaatgt
     9181 agatactata aataaaaaag acttatctat gccttatgga atatcaactg attatgataa
     9241 attgattgta gagactaaag aagcttacaa aaataatgat gtgatttttg tggagcttgg
     9301 agacacatat agattagatt tatataaacc aaatttaaat gaaaaaacat atgagagtat
     9361 gaaagataac atagaaaaaa atatagatat atatttaaaa aatatatttt ctatggttga
     9421 agaaaatgac actgtctaca tagcaagtgc atttccaagt gatttagatt ataaaaataa
     9481 aagaagactt tcgccaataa taaaattaaa tggagaaggg aaaggtatat tatcatcttc
     9541 aactactaga agagaaggta ttgtaacaaa tttagatgtt ggggttgaaa tattagacaa
     9601 ctttaatata aaaaatcaaa atatggttgg aagaaaatat gaacttatta acagagatga
     9661 taataaagaa tttttgatgg atgaatatca aaagatagta tctatttcaa gcataaggtc
     9721 tacaatactg aatggttttg taagtatagt tttcttgtca tggatagttg ctatgattgc
     9781 aattttattt agaaagcata tatcaaaaaa ttataaagaa acaacatttt ttatattaaa
     9841 ggaactttta aaaataggaa tagtaatgcc actgtcattt atgataacac caataatgaa
     9901 tttcaaaaca ccattagcaa tatctttagg aataattata ataacactta ctatatatct
     9961 tataagtaaa gttttaataa agaacgattt aaaaaacatg ctgtttttta ctggattaac
    10021 catagtaatt atggttattg atgctgggtt tggctcatat ttaatgaaaa gcaatgttat
    10081 gagttatgat tgtataattg gagctagata ttatggagta ggaaatgagt atcaaggtgt
    10141 ggcaatcggt agtgcaatat ttacatttgc aattttactt acatataaaa atataccaaa
    10201 atggtctata atagtttttt ctttggttat cttaattaca agtgcatctc caattatggg
    10261 agcaaatgtt ggaagtgcta tttctgaatg tgttgcattt ttactattta tactattgat
    10321 atataatgta aagatagatt tcaaaaaaat cgtattatta ggtatagcag tagtatttgt
    10381 attaggagtt tttgtagcaa tagatatgat tttgggaagt aattcacatt taggcatgtt
    10441 tgtaaaagaa atttacttta atggaccagg agaaataata caaacattta gtagaaagat
    10501 agagatgaat ttaaagctag ctcaaaccag tgcatgggta aatatactgt taactggaat
    10561 aggtgtaatt ttagttctta tgattaatca gattagatac tttaagcaac tgatggatga
    10621 gtatccaatt gtatttaaag gatttatagc atcaatagca ggatgtttag taactctttt
    10681 agtgaatgac tctgggattg tgtcatcagc tacagccttt atttatgtaa ttgtacctat
    10741 gataacatta agtataaatc ttacagcatt aaaagaataa gtactgtatg aataatatgt
    10801 aaatattaat acattaattt aacttcttta tttacaaaat aaagaagaaa gtttataaaa
    10861 aataaattat aataaaaaag agtttatctc aaaattgatt attctaatca aattttaaga
    10921 taaactcttt tttattataa agataaataa catataactt catattttag gtagattttt
    10981 tcttatatgt ttaggagtgc atttaaattt ttccttaaaa attctgtaaa ataattttgt
    11041 attagtaaat ccatgagctt ctaatatact gcataaggta tcatttgtat taattaagtc
    11101 tttataaata tgagaaatac gcacatcatt taaatactct aagtaagttt gtcccatata
    11161 ctgtttaaat tttctacaaa aatattctgg ttgtaagtgt gctaccttag cgattttgtt
    11221 aatagaaata ggcattttgt aattaatctt tgtatattct aaaactggtt caaattttga
    11281 caaatcaagt actgtttttt tcatattttt attacctaca gatattttaa agttagtata
    11341 taattcaaat aaaagttcaa ataataagct tgtaaagagc agattagctg caggaggaga
    11401 actaagttta atttctctca tgttttctaa tataagttta actttacttg aatttttttt
    11461 atagttattg tcattggcat taaccttaaa gtcaaaatag caatttttaa aatcagggat
    11521 atatttgttt agaaaagaca atggtacttg caataatata gaggtatttt gataaataca
    11581 tctagttgag tgaataattc cagaattaat gaacatacac tcattagctt ttaaattata
    11641 agtgtaaccc tccatgttaa tttgtaaatc accagaagtt atataaatta tttctaatga
    11701 gttatgccaa tgatttgcta cataactacc actatcatca aatagtttga aattaacatc
    11761 taaattatca ataggttcaa ttatttcatg tgaaaaatta tttctgttca taataatatc
    11821 ctccttataa ttttaaatta taaatagtaa atttataatg ttcaatatta aaaagataat
    11881 atagattaat aaattagata ataaacatac ttaagaaaac ggataaaatc aaatataata
    11941 actgtatatt aaaataactt aaaaaaatta ttttattata agtgcaaaat atacctattt
    12001 aaataagata agaggggagg attttatgtg tatataaaag gtgtaaattt aggaggttgg
    12061 ttagttttag aaaaatggat gacctcaagt ttatttgaag gcacagaagc tgaagatgaa
    12121 tactatttac caagacagct ttcaagagag gcatatgaat ctagaattaa gactcatcgt
    12181 agtgaataca tcacagagag agattttgca atgattaaat ctatgggatt taattcagtt
    12241 cgtataccag taccatactt tatttttgga gattgtgaac cattcatagg atgtgttaaa
    12301 gaacttgata aagcatttgc ttgggcagat aagtatgggc ttagtatatt gatagactta
    12361 catacagttc caggaagcca aaatggattt gataatggag gaatatcagg tatatgtagc
    12421 tggtcacaaa atccagaata tgtagcgttt acattaaatg tattagaaag acttgcaaaa
    12481 cgttatggga tgaggcatga attgtatgga atccaaattt taaatgagcc tataacagaa
    12541 agaatgtgga acataatgaa tgttccaaat cggtttaagg ctgtagataa ggagatggca
    12601 agggggagta aacctaattc attagagttt ttacgtgatt tttatataaa agcatataag
    12661 gtaatgcgtc cttatatgag ggaggaaaac gttatagtat ttcatgatgc atttgaatta
    12721 aaagcatgga aagactttat gagagaggaa gaatttaaaa atgttgttct agatacacac
    12781 caatatttga tgttagctga agcagatgga tgtgaacaaa gtattgatag ctatctcaaa
    12841 tatattaggg aaaattatgc taaagatatt ttacaaatgc aaaaatattt tcctgttata
    12901 tgtggggagt ggagcttatt taattcatat gcttgtggta tagatacaaa tggaggtcaa
    12961 tcacctctaa atgggattga atcaaatata gataaattat caaaagacga taaaagagaa
    13021 ttatatagga agatagcaaa agcacagctt gatgcatgga gaaatggaag tggtcactac
    13081 tattggaatt ataagttatt actagataca gttaatgaag aaggttggat aggatgggat
    13141 agttgggacc tagtcaaatg tgtagctcaa gaatggtatc ctatagaata ttaaactaaa
    13201 attggaggaa aagatatgat taaaaaccct atacttccag gttttaatcc agatccttgt
    13261 atttgtagaa agggagatga ttattatctt gtagtttcat cttttgaatg gtttccaggt
    13321 atacctgttt atcactctaa agacttaaaa aattgggagt tatatactca tattttgaca
    13381 gatgaaacaa aaatagattt gaagaagctt ccttcatcta aaggaatttg ggcaccctgt
    13441 ttgacttatt gtgaagaaga agatttattt tatatagttt atggaattat gaactctatg
    13501 aatgcaagat attttgatgt tgataattat ttaattacat caaaagatat aaagggagag
    13561 tggagtgaac cagtatatct acactcatca ggttttgatg cgtctatttt tcatgatgat
    13621 gatggtaaaa agtggattgc atcattagac tgggagacaa gagaaggata tgaaaaacct
    13681 ggtgttatat gtttagtgga atactgtaca aaaaagaaag aaatagtagg atatccaaag
    13741 agaatatggt cagggggaac tgatagaggt tgtattgaag caccacatat aacaaagcgt
    13801 ggagattact attatataat gtgtgcagaa ggtggaactg gatatggtca tagtgtaact
    13861 atgggaaggg ctaaaaatat atggggacct tatgaaaaag attcaatgaa tccaattgta
    13921 acttcaattc caggcgattt ttatgaaaga catgaccctg accatctaaa gcctaaatac
    13981 tataatccag aatcaaaact tcaaaaatct ggtcatggaa gctatataga aacaacatca
    14041 ggtgaagtat atttagttca tctaacatct agaccatttg taccagagtt aaggtgtact
    14101 ttaggtagag aaacagctat tcaaaaaatg aaatggacaa aggataattg gcttcgaatg
    14161 gaagatgaaa gtaatttggc aaaagaatac gtatcagaaa gtaaactaga agaacattta
    14221 gtttcatcta taccaagttt tgatgacttt gattcaaatg aattaggttt acagtactat
    14281 gctcctagga tttcaccatt atcatttgca gatgttaagt ctagaccagg atatgtaagg
    14341 attagaggac aagaatcaag aacatcatta aataaagtga gcatattggc aagaaaatta
    14401 acttcagtat atgcaagaat aaccactaag atggagtttt acccagaggt acatcagcat
    14461 agtgcgggtt tgataatgta ttatgataat atgaattata taaatttaag aaagtattat
    14521 agtgaaacat tgggtcaaag tgcactatca ataatacatc ttgaaaatgg agagaaaacg
    14581 gaatttttaa atactaggat accaataaaa gatataccaa tatatcttcg tctgtatgta
    14641 caaggtcgta agtcatattt tgaatggagt tatgatgaaa aaaactacca gagaatagga
    14701 aaggtatttg atacaactaa gttttcagat gagtactgta aatatggaga atttacaggt
    14761 acgtttatag gattaacttg tgcagatcgt gtaaagcata aacactatgc tgattttgat
    14821 ttttttgaat atatagtaga tgaatcaaaa gatgtcgatt aataaaatca ttactaaaat
    14881 tttcagagca aaggtaaatc ttatgctctg aaataagaaa cattagaagg caaatcttac
    14941 aaaaaggagt atggtattat gaatacagaa gttaatgtta aagcaactac gattagatat
    15001 gaaaagattt cattttttga aagaatttct tatggttgtg gggatttggg gtgcaatatc
    15061 atatactcag ctatgtcagc atttttgctg ttttattata ctaattatgc agatgttagt
    15121 gcagcagctg taggtagtat tatgcttgta tctaggatac tggatgggtt tagtgactta
    15181 acaatgggaa ttatagtgga tagaactaaa tccaaatacg gtaaggctag gccttggatt
    15241 ttgagaatgg cgattccttt tgctatagca gcagtattat tattttctgt tccatcaaat
    15301 cttggtatca cttctaaatt aatttatatt tttattacat ataacttagt ttctactgtt
    15361 atttatacag caatcaatgt accctatgca actctaaatt cacttataac tcaaaaccag
    15421 tatgaaagag gagtattaag tatatttaga atgatattag ccacttgtgg taccttacta
    15481 ataaatggac ttacactacc tctagttgaa tactttggaa ataatttatc agcatggact
    15541 aaaacattct ttgtatttgg aatagcatct ataatggtat tttttataac atttactgga
    15601 accaaggaaa gagtaaaagc agttaagcaa gataggaatg aagtaatacc atttaaaata
    15661 ggtattaaat ctttatttag aaataagtac tggatacaaa taacattatg tttagtttgc
    15721 atatttattg tatttgcgat aaatggtggt tcatccgtat attatgcaaa gtttattttg
    15781 ggagatgaaa aattatttgg tcctataaat atggtttcaa atatatccca aattatagct
    15841 atgtttatgg ttgctccttt tataaaaaaa tttggaaaaa gaaatgtatt aatagtaggt
    15901 tcaataatat taatatcgtc aaatgttatg tttataatag ttggacaaaa tcatatagga
    15961 gtaatatttg caagtgctat aaagggaata ggaagtgctg gaatagcatc aacaatgttt
    16021 gctattgttt cagatactat tgaatatgga gaatggaaga ctggatatag aactgagggg
    16081 cttataaata gtgcatctag ttttgggttt aaagtgggaa atggattagg ttcagcaata
    16141 ttaggtgcag tattatcaat tggtggttat gtaggaacat cagctactca aagtgattta
    16201 gctatagtat caataaaagt atgttttata tacctaccta tatttataac aatattacaa
    16261 attatcataa tgtcttttta taagcttgat aaagaatata gtactatact taatgaatta
    16321 aatactaaat aatgaaaaag tttcttataa agtcttaagt ttaattaagg tctattgtaa
    16381 atgttcccta taaaaactat tatatattta tgattattga agaattttta gagaagcgaa
    16441 taataaaaat ataagaagac tttaaatgat gaaatggttg gttttttaga agtgatttaa
    16501 taagttattg ttatttaaag cattataagt ggacaattaa tttttaattt atggagatga
    16561 tatttaacaa ttagaagtaa tatataatat gcactaagaa gcaatttttc aactatttat
    16621 gaaggtggtg gtacaagaaa agtatcacct tttttttgtt atacaaaaaa acagttgact
    16681 ttttatatga accccttcta taatgttact gaaattaagt aaaatgattg aacaaatgta
    16741 aagataattg aaaagcttga ttttggagga aagcaaatga aaaaaattgg agacttaaga
    16801 ttaatgatga agtgttgttc actttattac gaagataatt tgaatcaaca ggaaatagca
    16861 aatcaattgg gaatatcaag accaacaata tcaagaatat taaaagaagc ttttgaacaa
    16921 ggaatagtaa aaatacagat agttgatgtt ttgaaaaatg attaccaaaa aatagagaga
    16981 agtttggaga gaaaatataa attaaaagaa gtaatagtag tagatgataa acaggatgca
    17041 ctaacacaaa aacaagaact agcaagagct gtatctgaat atttaactag agtagtaaag
    17101 gaaaatgata taataggtgt ttcaatagga acaacactaa aagaaatacc aagatatgtg
    17161 gaaaaaagta actgtaaaaa tgttacattt atacctctat taggagggat tggagacaat
    17221 gaaatagata ttcatgcaaa tcaaatagcc gtaagtttag cgagggcttt tggaggtgat
    17281 tttaaattat tacatgctcc agctgttatg tctgacttgt ctacaaaaga gaaactttgc
    17341 aaagacgaaa aaattaaaga agtactagat ttaatagata aaacaactat agcaattgtg
    17401 ggtataggaa atcctatgag tttaaactca acaataatgg cttctggata catgaatgaa
    17461 gcagatatag aagatttaaa aaaatacaac tcaataggtg caatttgttt acaagccttt
    17521 gataaagaag gaaaaacttc tatacttgaa tttaatcaaa gagtattagg agtgaaactg
    17581 gaagatttaa aaaagataaa aagaacaata ggtgtcgctt caggagatga aaaaatagag
    17641 gcaataaagg catcattaaa agcgaaattt ataaatagtt tagcaattaa tcacagttta
    17701 gcacttaaat tattagaaga ttgtgactaa tagaaagata gataaaagtt aacaggaggg
    17761 aatgtatatg tcaatatcaa aagaaacatt gcttgaaatg tataagagaa tgaatcaggc
    17821 tagaaaattt gaagagaaag ttagttggtt ttttgcaaga ggtatggttc atggaacaac
    17881 tcacttatct gtaggtcaag aagcgtcaag tgtggcggct gtaatggctt tagaaaaagg
    17941 agatttagta tcattaactc atagaggaca tagtcaattt ataggaatgg gaatagacct
    18001 aaataaaatg atggctgaac ttatgggtaa agaaactgga ttttgtaagg gaaaaggagg
    18061 ctcaatgcat atagcagata ttgagtcagg taacttagga gcaaatggag ttgtaggtgg
    18121 aggtcttaca atagctccag gagctgcact tacacaacag tataaaaaaa caggcaaaat
    18181 agttttatgt agttttggtg atggagcatc aaatgaaggt acttttcatg aaggaataaa
    18241 tttatcttca atatggaaat tgccaataat attttactgt gagaataatt tatacggtat
    18301 gtcaacaagc ataaaacgtc atatgaatat agaaagtatt gccactagag cagcttctta
    18361 tggaatagaa ggaatatcaa tagatggata taacccaata gaagtatacg aaacagtaca
    18421 aaaagctgct gagaagtgta gaagaggaga aggacctgta ttaattgaaa gtagaactta
    18481 tagatggtta ggtcattcaa aatcagatgc aaatgtatat agaacaaaag aagaaataga
    18541 atcatggaaa gcaaaagacc ctattgaatt tttaaaaaat tatcttatag aaaataatct
    18601 atctaatgaa gatgaattag ataagattca agaatttgca aagcaatcaa tagaagatgc
    18661 agtagagttt gctcaaaata gcccaaatcc aaaaatagag tctttattag aggatgtata
    18721 tgcagactaa gaatggtaaa ggaggaaaat aaaaatgagt acaagggaat taacatatgc
    18781 acaagcaata aaggaagcaa tgtcagaaga aatgagaaga gatgaaaatg taatatttat
    18841 gggagaagat ataggaatat atggaggagc atttggtgta tcagttggta tgatagatga
    18901 atttggacca gaaagagtaa gggatactcc tatatcagaa gcagctatag caggagcggc
    18961 agcaggtgca gcagcaactg gcttaagacc tattatggaa gtaatgttta tggactttgt
    19021 aacaatttct atggatgcaa ttgtaaatca agcggcaaaa atgagatata tgtttggagg
    19081 aaaagcacaa gttccaatgg ttgttagatg cccaggaggt tctggaactg gttcagcaga
    19141 gcaacattca caaagtttag aagcttggtt ttgtcatgta ccaggagtaa aagtagttgc
    19201 accttctaca ccagcagatg ctaagggatt gttgaaagca gctataagag ataataatcc
    19261 agtcatattt gttgagaata aattgttata cagaaaaaaa ggttttgtgc cagaagatga
    19321 ctatgtaatt gaaattggaa aggcagatat taaaagagag ggtactgatg ttacagtaat
    19381 tacttatgga agaatgttac aaagtgttga agaagcagca gagactctat caaaagaaaa
    19441 tataaatgtt gaaattatag atttaagaac tttatatcca ttagataaag agactatagt
    19501 aaagagtgta tgtaaaactg ggagagtttt aatttgccat gaagcagcta agactggtgg
    19561 gctaggtgga gaaatatcag cactgataac agaaagtgaa tcatttgatt atttagatgc
    19621 tccagtaaaa agaatttgtg gaaaagatgt gccaatacca tataatccag agttagaaaa
    19681 agcagttgtc ccaagagttg atgaaataga agaagcaata aaatctttaa ttgttagata
    19741 aggagggata gatatggtgg caaataaaat aaaagccaca ccagcagcta gaagtcaggc
    19801 aagaaaagac aatataaaat tagataggct gattggaagt ggagaaaatg gaaggattca
    19861 tttagtagat gtgttaaatt atttaaaaga taataaagca aatactactc ctttagctag
    19921 aagaatagca gaagatttaa atatagattt agaaactatt gtaggtactg gatataatgg
    19981 aaagataaga aagtgtgatg tggaaaaatt aactgcaaaa gaaactattg tatcgactaa
    20041 tacatctaaa tctagtgaga aaaaagagct gaaaattgaa aatgaaaatt caagcatgtt
    20101 taacacagta gaaggaatat ttgaaaagcc aaatccaatg agagctactg tagcaaaacg
    20161 aatgtcagaa agttatttta gtgctcctgt atttacattc aatatagaag tagatgctac
    20221 agaattgaag gtacttagag caaagttaat cgacacagta aaagaatcaa ctggagtaaa
    20281 attaactatg acagatttaa tagtaatggc agtatctaaa atacttccaa atcatcaagc
    20341 cttaaattca gcatggacag atgagggtat atttagatat aaagatgtaa atatagctat
    20401 tgcagttggt ttagatgaag gcttatatgt tccggtagta aaaaatgcaa acaaaaagtc
    20461 tttaaaagaa atagcaaaag aaagcaaaga acttgcggaa aaagtaaaga cagggaaact
    20521 tatgccagca gaccaagaag gtaatacatt tacaataagt aatgttggaa tgtatggtat
    20581 aactacattt acacctataa taaatatgcc ttcaagtgca atcttagggg taggtgctac
    20641 acaagataag tttgttccag taaatggaga ggctaaaata aaacctataa tgaacttatc
    20701 attaacatca gaccatagag taatagatgg aacagtagct gcaaaattct taaaagattt
    20761 aaaagaattg ttagaaaatc ctttatcaat gcttgtatag gttttgatat tttgttactg
    20821 atataaatag tttgaataga ttatattatt ataattgttt cagtaaattt aaagctttta
    20881 tatattaaga attattttta acagtaacta tatgtgaata tgatttgctt aattaaaata
    20941 taagaaaata aataggagga gagcctatgt cagtagaagt aataatgcca aaagcaggag
    21001 tagccatgga agaaggtact atagtatctt ggctaaagca agaaggcgaa gaagtaaaga
    21061 ttggagaacc tatactagaa ataacaacag ataaagttaa tatggagata gagtcagaag
    21121 gagaaggtac acttgctgta atcatacata aagaggaagg tgaagtatta ccagtattta
    21181 cagtaatagg tgtaatagca gaaaaagggg aaaatcaaga ggaagtaaaa gctaaatatt
    21241 tatctggaaa tgtttcaaaa gaagatatag ttgaagagaa tcaaaatata gaatttaaag
    21301 aagaaaaaat aaacaaaaaa gagtgtaatc atgattatga tgtagtggta ataggaggag
    21361 gacctggggg atatttatca gcattaaaag cagctctttt aggtggaaga gttgctttag
    21421 ttgaagaaaa tatactagga ggtacttgct taaatagagg ttgtatccct acaaagactt
    21481 atataaaaac agcagaaata ttagaagaaa ttgaccaatt atcaaagaga ggtgtaaaag
    21541 taactgtaga taaagaacag gacattaaga aggccataaa atataaaaat agagtagtta
    21601 aaaaacttac agctggtgtt ggcggattat taaaaagtag agatgtagat gtgtttaatc
    21661 ttaaagctag tgttaaagaa gagcataaag taattttatc agatggaaaa gttttagata
    21721 cagaaaatat aataattgct acaggttcca aagtaaggat attacctata aaaggaatag
    21781 aatcaaattt aataataact agtacagaag cattagattt ggaaacagtg ccagaagaat
    21841 tagtaataat tggtggtgga gtgattggtt gtgaatttgc agagatattc aattcaagag
    21901 gttctaaagt aactatagta gaaatggaag atagagtaat cccaagaatg gataaagagt
    21961 taagcgaatc tttaaaatat tctcttagta aaaaaggtat aaatgtatta actaaaaaga
    22021 aagtttctga atttaaagaa gaaggaaata acatattagt gtgcattgaa ggtgaagagc
    22081 caataaaagc agatttatgt ctatatgcta taggaagaga agctaatctt tctggcatag
    22141 aggacttaga tattaaaata gataaaggtt caatagttgt aaatagtaaa atggaaacaa
    22201 gtataccaag catatatgca gtaggtgatg ttactggagg tgtaatgtta gctcatgctg
    22261 cttttaaaat gggagaggta gcagcttcaa atgctctagg tgtgaataaa gaagttgact
    22321 taggtgcatt acctagttgt gtttatacaa ttccagaagt agcatcagtt ggtattacag
    22381 aagaggatgc tagaaaaaaa tataatgtaa aagttggtaa gtttaatttt gctggaaatg
    22441 gaagagcttt agcttctggt caagaacaag gatatgtgaa ggtagtagca gatgctaaat
    22501 atggagaaat tttaggtata catatgtttg gatgtggtgt agcagaactt ataaatcatg
    22561 cagcatcatt taaagcatta gagataccta ctgatgaagc aagtgagttg atatttggtc
    22621 atccatgtac ttcagaagct ttaatggaag ctttggcaga tgtaaatgga gaatgtttac
    22681 acttacctaa aaaataaatc taaacataaa ttattaattt aagtctatta ttaatattaa
    22741 tttatatcat aaaattttaa aacacttact tagccatacc ccttattatg caaataattt
    22801 atttgcataa taaggggtat tttttatg
//
LOCUS       DAYAOO010000067        22126 bp    DNA     linear   BCT 12-OCT-2024
DEFINITION  TPA_asm: Clostridioides difficile isolate ST8-SSI-h139-18
            SAMN40601845-rid21577343.denovo.067, whole genome shotgun sequence.
ACCESSION   DAYAOO010000067 DAYAOO010000000
VERSION     DAYAOO010000067.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN40601845
            Sequence Read Archive: SRR28438827
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 22126)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 22126)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-MAY-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-MAY-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002157583.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002157583.1
            Genome Coverage       :: 163x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/11/2024 16:19:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 4,038
            CDSs (total)                      :: 3,963
            Genes (coding)                    :: 3,930
            CDSs (with protein)               :: 3,930
            Genes (RNA)                       :: 75
            rRNAs                             :: 6, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 60
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 33
            CDSs (without protein)            :: 33
            Pseudo Genes (ambiguous residues) :: 0 of 33
            Pseudo Genes (frameshifted)       :: 7 of 33
            Pseudo Genes (incomplete)         :: 25 of 33
            Pseudo Genes (internal stop)      :: 11 of 33
            Pseudo Genes (multiple problems)  :: 8 of 33
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..22126
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN40601845-rid21577343.denovo.067"
                     /isolate="ST8-SSI-h139-18"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Denmark"
                     /collection_date="2018"
                     /collected_by="Statens Serum Institute"
     gene            complement(337..528)
                     /locus_tag="ACGI5H_002741"
     CDS             complement(337..528)
                     /locus_tag="ACGI5H_002741"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9698438.1"
                     /translation="MDDFSKLKSLYEDGYRCIYHDCVDNNYTIYLKNFYTEGSETIEL
                     SSESDFSQFKDYIDGLRMS"
     gene            748..1794
                     /gene="cobT"
                     /locus_tag="ACGI5H_002742"
     CDS             748..1794
                     /gene="cobT"
                     /locus_tag="ACGI5H_002742"
                     /EC_number="2.4.2.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009906494.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008939 -
                     nicotinate-nucleotide-dimethylbenzimidazole
                     phosphoribosyltransferase activity [Evidence IEA];
                     GO_process: GO:0009236 - cobalamin biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="nicotinate-nucleotide--dimethylbenzimidazole
                     phosphoribosyltransferase"
                     /protein_id="HFG9698439.1"
                     /translation="MSLLESISKNIYSLDNSSIEKTKQRLDRLIHPTGSLGKIEDICM
                     QLAGIFGNENFDTSKKVIIAFAGDHGVYEEGVAPDPQNITKLQFPNFSKGLCGVGVIS
                     KFVGADVVAVDVGINCDEKLDGVLDYKIRKGTSNMAKGPAMSKQEAIRCLEIGIEIAE
                     QCIEKDYKVIGIGEMGIANTTPSTAIISVISGCDPLEVTGIGAGLKKERLKHKAEVIR
                     KAIEINNPNPTDGVDILSKVGGFEIGSMAGVILGCSANRIPVVIDGFISYAAALIAYK
                     INPKTREYMIASHLSAESGTKRALDILKLDPLLNMDMRLGEGSGAALAFDIIEASNYT
                     YKNMATFDEIDMGR"
     gene            1826..2386
                     /gene="cobU"
                     /locus_tag="ACGI5H_002743"
     CDS             1826..2386
                     /gene="cobU"
                     /locus_tag="ACGI5H_002743"
                     /EC_number="2.7.1.156"
                     /EC_number="2.7.7.62"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009906489.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0043752 - adenosylcobinamide kinase
                     activity [Evidence IEA];
                     GO_process: GO:0009236 - cobalamin biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional adenosylcobinamide
                     kinase/adenosylcobinamide-phosphate guanylyltransferase"
                     /protein_id="HFG9698440.1"
                     /translation="MSKIILVTGGARSGKSNFAEKLCFDRNNNTAYIATSIPFDDEMK
                     DRVKKHQENRPRNWNTYEIYEDIYSIIKEIYKEHETVILDCVTLLVNNLMFEHNLNIE
                     ESSQEEINKLEQYIKEQVVKLIEEIEKTNLYFVFVTNELGMGIVPGNKLSRIYADIVG
                     RINQYIASKSNEVYFVVSGIAMKIKE"
     gene            2396..3169
                     /gene="cobS"
                     /locus_tag="ACGI5H_002744"
     CDS             2396..3169
                     /gene="cobS"
                     /locus_tag="ACGI5H_002744"
                     /EC_number="2.7.8.26"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008818 - cobalamin 5'-phosphate synthase
                     activity [Evidence IEA];
                     GO_function: GO:0051073 - adenosylcobinamide-GDP
                     ribazoletransferase activity [Evidence IEA];
                     GO_process: GO:0009236 - cobalamin biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="adenosylcobinamide-GDP ribazoletransferase"
                     /protein_id="HFG9698441.1"
                     /translation="MKRFILILQFLTRIPIKLNVGFDDEFYKSIVYFPLVGFVIGILS
                     YLIGWISMLLFEPFIASIIITLAGVLITGGLHIDGLGDTFDAIYSYRDKEKMLEIMKD
                     SRLGTNSLLAIMFVLLLKVGFVYDIISNNSLWVIIFMPMIARLGVMLLTYKTVTPREK
                     GMGNLFIGKLTTSMLITAIIYTLLIVALITKFIFLLPNIVLIKVLGSIIVVFVFIILF
                     KKHIYKKIDGVTGDILGCGIELSELVYLIYIYLLIFMFF"
     gene            3189..3803
                     /locus_tag="ACGI5H_002745"
     CDS             3189..3803
                     /locus_tag="ACGI5H_002745"
                     /EC_number="3.1.3.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894012.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine phosphatase family protein"
                     /protein_id="HFG9698442.1"
                     /translation="MIRLILIRHALTNDNKKGRLSGHINSCISEEGKLQINKITRYLS
                     NENIDKVYTTPSTRTKDTVEKISKLKLLEIEEKEALREISFGDFEGRTFEEIKIKYPN
                     EFEKMIKEGNNYRYPNGESLIDSYKRVAKEIDNIILENNSNLDTKTILICSHAGTIRN
                     IITHLISGSYKYHWNFKIDNASITVLEIDGGFAVIDKMNFTDFI"
     regulatory      3870..4049
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00174"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="cobalamin riboswitch; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="adenosylcobalamin"
                     /db_xref="RFAM:RF00174"
     gene            4164..5678
                     /locus_tag="ACGI5H_002746"
     CDS             4164..5678
                     /locus_tag="ACGI5H_002746"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437761.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003824 - catalytic activity [Evidence
                     IEA];
                     GO_process: GO:0009236 - cobalamin biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cobyric acid synthase"
                     /protein_id="HFG9698443.1"
                     /translation="MGKKIMLQGTASNVGKSVLVAGLCRIFKQDGYTVAPFKSQNMAL
                     NSFITKEGLEMGRAQVFQAEAAKIEPIADMNPVLLKPSGNNKSQVIVRGKVVGEMPSS
                     KYHDYKLELVDVLKETFNSLNSRYDIVVMEGAGSNAEINLKDRDISNMGMAEIADAPV
                     IIVGDIDRGGVFASLAGTMLLLNEDEKRRVKGVIINKFRGKKELLQDGVKMLEDIIKV
                     PVIGVVPYTDIKIEDEDSVTTRFKKKMNKSDIHIEIIRTPHMSNFTDFNIFETQEDVS
                     IRYVDYGESLGNPDILIIPGTKSTIDDLTYIRKSGLESQIKNLHSQGKLIFGICGGYQ
                     MLGKKLKDPYHVESEIEEVDGIGLLDTETTFEKEKTTTQVEATIVECISEYMNNLKGK
                     KVKGYEIHMGITKRGNDVRSLDLITKKLDKEVNYTEGSVNKEGNVIGTYLHGIFDEIS
                     FTRAILNNIRKKKGLGELESKVNSFNEFKDKEYDKLADFLREHLDIEKIYEIMK"
     gene            5717..7093
                     /locus_tag="ACGI5H_002747"
     CDS             5717..7093
                     /locus_tag="ACGI5H_002747"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421301.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042242 - cobyrinic acid a,c-diamide
                     synthase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cobyrinate a,c-diamide synthase"
                     /protein_id="HFG9698444.1"
                     /translation="MKKILIAGTNSGVGKTTISLGIMQALVKRNMKVQPYKVGPDYID
                     PSYHTFITGRHSRNLDSYMLDDEKIKYIVNKSSKDADISVIEGVMGLYDGFGIDLDNC
                     TSSHTSKVLKSPVILVINGKSMAASSAAMVLGYKELDKDVNIKGVIVNNVKTNSHYQI
                     IKSSIEKYCNVEVLGYFPPNNKFSLESRHLGLVPSVEMKSLREKFYTLADEIEHYIDI
                     DRIIEISESDEFESDFDFQTLIENNKIKEHVNNKSIAIAYDKAFNFYYRENIELLEEL
                     GLEINYFSPLEDVSVPNADYIYIGGGFPEIFGKELEANESMRTSILEAHNNNIPIYAE
                     CGGLMYLGEKLLNQEEQEFNMVGIFSGISKMTSSLKRFGYCIGVAKENTLLSKKGESI
                     KGHEFHHSIFESDEKCVYSMRKERDGNIVEEWDGGYSKGNTLATYLHTHFYNNLNCIE
                     NFLKKGNE"
     gene            7094..8065
                     /gene="cbiB"
                     /locus_tag="ACGI5H_002748"
     CDS             7094..8065
                     /gene="cbiB"
                     /locus_tag="ACGI5H_002748"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903766.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0048472 - threonine-phosphate
                     decarboxylase activity [Evidence IEA];
                     GO_process: GO:0009236 - cobalamin biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="adenosylcobinamide-phosphate synthase CbiB"
                     /protein_id="HFG9698445.1"
                     /translation="MSILSIYIGYVTDLIVGDPYSFPHPVRFIGKLINFTQGIIRKVS
                     KNDRQLKFGGFILWFITVGITYLTTYAIVKLFSFNILLSIVVNSFIIYTTLATKCLKD
                     EALKIYNVLKTEDIEKSRIQLSYIVGRDTTNLSEPEIIRATVETVAENTVDGIIAPMF
                     YAFIGGAPLAMAYKAINTLDSTVGYKNKKYKDIGFASAKIDDIANYIPARISVILMTI
                     GSFFLNYNYRNCFKISIRDRKNHKSPNCAFSEGAVSGALGIQLGGTNVYFGEKVYKPT
                     IGDKLREIDKEDIIKTNKIMYASSFVSMLVFTLIYVLCRMILINLII"
     gene            8097..9167
                     /locus_tag="ACGI5H_002749"
     CDS             8097..9167
                     /locus_tag="ACGI5H_002749"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903764.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA];
                     GO_process: GO:0009058 - biosynthetic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="aminotransferase class I/II-fold pyridoxal
                     phosphate-dependent enzyme"
                     /protein_id="HFG9698446.1"
                     /translation="MKDLGHGANVDEMARLYGKNPKEIIDFSSNINPNVLPNLERYIL
                     KGLEECRNYPDINYTNLRENISKYIDINPDFIIPGNGATEVIYLLMKSIKKKLAIINP
                     TFSEYRRSAELNNLDIIDLELDLENNFKLNIDIIKENIKRFDSLFICNPNNPSGNVQD
                     LKELVHLLDKHNKVLIIDETFMEFVEDESKYSLVKYIESNKNIFIIKAVTKFFGMPGL
                     RLGYGLTSNTEIMNKIYEHKEPWTINSFADILSNFIFEDKEYIKNSKEYYIEERKYML
                     QELRNIRNIKVYDTDANFILIRIYKKTTKELKKDLFKQGNILVRDASNFIGLDDSFIR
                     VAIKSHEDNKILIENMKNLLGD"
     gene            9169..10056
                     /locus_tag="ACGI5H_002750"
     CDS             9169..10056
                     /locus_tag="ACGI5H_002750"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729308.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cobalamin biosynthesis protein"
                     /protein_id="HFG9698447.1"
                     /translation="MKSYGICPASCGEFVQGIIDDEEYLCSYAIDMYSKVYIEEKLVD
                     INLGRYKSRLAIEKVFEKFNLPKKYTKNISLNINSKIPVGKGMASSTADIGATIKATL
                     SLIDKDLSSEEISKLAAEIEPTDSIFIDKNSIFNPLNGTVIKYLGNLTNAKVVILEPN
                     KVLDTMKIRLRQDYNKLKVENKEVIKKSFALLEEGLKKNNLSLVGEACTLSSLANENI
                     EKKEYLNEIIKISKKYGAYGVNIAHSGTVVGILIDKFMNDKKMIDALCESNINSVYNK
                     IYTQNIINGGIKGEIEWNT"
     gene            10044..10676
                     /locus_tag="ACGI5H_002751"
     CDS             10044..10676
                     /locus_tag="ACGI5H_002751"
                     /EC_number="5.4.99.60"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425750.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cobalt-precorrin-8 methylmutase"
                     /protein_id="HFG9698448.1"
                     /translation="MEYIKNPMKIEEKSFELIQEIIDEIRPDYKFKNNIEEKIIKRAI
                     HTTADFDYLDILKISEEAVDSIIDALKNNASIYTDTNMALSGINKRKLESLGCKYKCL
                     VADDETVKLAKEKGITRSMAAVEIAAKEEGRKIFVLGNAPTALYKVMEMKSEGRLDLD
                     AVIGVPVGFVGAQESKDEVEKTDIPYIISKGRKGGSNLAAAIVNAILYTM"
     gene            10685..11911
                     /gene="cbiD"
                     /locus_tag="ACGI5H_002752"
     CDS             10685..11911
                     /gene="cbiD"
                     /locus_tag="ACGI5H_002752"
                     /EC_number="2.1.1.195"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421296.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_process: GO:0009236 - cobalamin biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cobalt-precorrin-5B (C(1))-methyltransferase
                     CbiD"
                     /protein_id="HFG9698449.1"
                     /translation="MEEYVYIDGKKYRRGYTTGSCATGASKAAVYMLITKNRINTINI
                     DTPKGIPLLLKVDNINISDTFVECSIKKDGGDDIDATHTMDIYARAEIVAKNDKNKGY
                     LTLKDIDNLSTNSECKSELYKFIRVYGGTGIGVVTKKGLSVDVGKPAINPTPLKMINH
                     EIRKLIGDNFESILGNDKVLKITIFAPQGETVAKKTFNPRLGIVGGISIIGTTGIVEP
                     MSDEGWKKSLSIELQMKKEQGLDKIILVPGNHGEQFIREKLNLDIKYVVRVSNFIGYM
                     IKEAQRIGYKKILMAGHIGKFIKVSAGIFNTHSKVADARSEILVANLALMGARYEFLN
                     KINQCVTTEEAVELINNSEYREVYNILSNKCRERVKQYLNEDSDDIDVEVIIFSMDKS
                     LLGKSDNTDDLVEVFI"
     gene            11908..12516
                     /locus_tag="ACGI5H_002753"
     CDS             11908..12516
                     /locus_tag="ACGI5H_002753"
                     /EC_number="2.1.1.289"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903759.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cobalt-precorrin-7 (C(5))-methyltransferase"
                     /protein_id="HFG9698450.1"
                     /translation="MINIIGLGPGNLDYITKKGENLISTSDVLIGGKRNLESIKNFEG
                     EKIVLDSNLREIIEYINNNKEKQISIIASGDPLIYGIGRYLSKNIDNKMLNMVSGISS
                     LQYIFSKIYVDMNDVYITSSHGKVPDFDYILSHKKVCMVTDSKIGPKQISREIIDRNL
                     NKIIVVGENLSYDNEKITIAKPEEIIRMDNFDMNVVVILDEE"
     gene            12506..13081
                     /locus_tag="ACGI5H_002754"
     CDS             12506..13081
                     /locus_tag="ACGI5H_002754"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898664.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008276 - protein methyltransferase
                     activity [Evidence IEA];
                     GO_process: GO:0009236 - cobalamin biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="decarboxylating cobalt-precorrin-6B
                     (C(15))-methyltransferase"
                     /protein_id="HFG9698451.1"
                     /translation="MRNSEFITGKVPITKEEVRAISISKLNLVNAKNLIDIGAGTGSV
                     SVEAAYNYPNLKVISIEKNDDAIELIEKNKKKFNLKNIEVIKGYAPINLGLNVKVESI
                     FLGGTGNNLEEIIEWSKKNLVTGGRLVANFIIIDTFNQTLKLLKKHGFKEIDVCVLNV
                     SKLEKLGKGEYFKPLNPIYIISCEKGENDDE"
     gene            13074..13826
                     /locus_tag="ACGI5H_002755"
     CDS             13074..13826
                     /locus_tag="ACGI5H_002755"
                     /EC_number="2.1.1.271"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009906481.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cobalt-precorrin-4 methyltransferase"
                     /protein_id="HFG9698452.1"
                     /translation="MNKVHFVGAGPGDKELITLKGYKLLSNADVVIYAGSLVNPELLE
                     YCKEDCQIHNSAHMDLQEIIDVMREGIENNKSVVRLQTGDFSIYGSIREQVEDLNKLN
                     IDYDCTPGVSSFLGAASSLGVEYTVPEISQSVIITRMEGRTPVPEKESIQSYAKHQTS
                     MVIFLSVQEIEKVVSKLLEGGYPKDTPIAVIYKATWADEKIVKGTLSDIAVKVKENNI
                     NKTALIMVGRFLGEEYNNSKLYDKDFKHEYRG"
     gene            13810..14931
                     /gene="cbiG"
                     /locus_tag="ACGI5H_002756"
     CDS             13810..14931
                     /gene="cbiG"
                     /locus_tag="ACGI5H_002756"
                     /EC_number="3.7.1.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425735.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cobalt-precorrin 5A hydrolase"
                     /protein_id="HFG9698453.1"
                     /translation="MNIEGNIAIICITENGKKLALKINSLVNNCVIYQVKNKKSNLVV
                     EETCVHTVQKKLSDFVGEIFSKFDYIVFIMATGIVVRSIAPYIISKFSDPAILVMDEK
                     GKNVISLLSGHIGGANSLTQYISSLIDANPVITTATDINQKASLDMIAKKLNAHIDNF
                     RESVKEVNSMLVNNKCVGLYVDEGYQVDTRGFKLIESKDELRDSFSNTYIEKLVVVSN
                     KINCIEDIENLNLDNKFEHCYSTQKIIKVIPRDIVIGIGCRRNTDSELMYNSLEEFLN
                     KQNIDIRAINTVGSIELKKDEKAIIELSKILKVPFKTFSVDEISKVDNLFDKSDFVKK
                     NVGVYSVAEPVAYLLSKGNLLVEKHKYKGITFSVGRIKI"
     gene            14928..15653
                     /gene="cobJ"
                     /locus_tag="ACGI5H_002757"
     CDS             14928..15653
                     /gene="cobJ"
                     /locus_tag="ACGI5H_002757"
                     /EC_number="2.1.1.131"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898660.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0030789 - precorrin-3B
                     C17-methyltransferase activity [Evidence IEA];
                     GO_process: GO:0009236 - cobalamin biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="precorrin-3B C(17)-methyltransferase"
                     /protein_id="HFG9698454.1"
                     /translation="MIYVVGIGPGSKDTMTLEAIKAIEDSEAIVGYKTYIKLIEEFIQ
                     GKEIIQNGMRQEVDRCKQAVEEAKKGKKVAVVSSGDAGIYGMAGLILELISKEDEDIK
                     VKVIPGVTASIGAAAILGAPIMHDFCHISLSDLMTPWEVIEKRLRLAAEADFVICLYN
                     PRSKGRSEHLSKAFKIMGEFKGGDTPVGVVKDVGREKEEKFVCTFENMDFEKVDMTTM
                     VIIGNKSTYINGELMITPRGYTV"
     gene            15650..16402
                     /gene="cobK"
                     /locus_tag="ACGI5H_002758"
     CDS             15650..16402
                     /gene="cobK"
                     /locus_tag="ACGI5H_002758"
                     /EC_number="1.3.1.54"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425730.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016994 - precorrin-6A reductase activity
                     [Evidence IEA];
                     GO_process: GO:0009236 - cobalamin biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="precorrin-6A reductase"
                     /protein_id="HFG9698455.1"
                     /translation="MILILGGTSDSLSICDKINELKNQPYILSVTTDYGRELAQQHAE
                     NVILGKLGKEDMLKFIKDNNIVKIIDATHPYAVEVSKTAITCAKLLNIDYIRFERKSL
                     IEEIDYDNKFIVDTIEEACEIANKIGTNIFIGTGSKNLNRFIEEISDKNLVVRVLPTS
                     EVILSCEKLGLSADNIVAMKGPFSQYINEETYKHYNIDLVITKESGIAGGFLEKVNAC
                     KTFNIPVIIIKRESINYENVFNDINKIKDILV"
     gene            16421..17899
                     /locus_tag="ACGI5H_002759"
     CDS             16421..17899
                     /locus_tag="ACGI5H_002759"
                     /EC_number="2.1.1.151"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891951.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cobalt-factor II C(20)-methyltransferase"
                     /protein_id="HFG9698456.1"
                     /translation="MKKALLVVSFGTSYHETREKTIDICEDKIKNSLKSHDFFRAYTS
                     NMIINKIKKRDGIEIDNPIQALDKIYEQGYDEVIIQTLHIICGEEFNKLKEQVDGYSS
                     KFKKIVLGRPLLTHIEDYQEAVEAIKHQIPHMESNEAVVFMGHGTLHESHSAYPALEY
                     MLRDNGINAYVGTVEGYPEIEHVIRRLKEGNIKTVNLMPFMLVAGDHAINDMAGDEED
                     SWKTILEENGFNVRVHLKGLGENSYIQDKFVRHAVKCAENAKFYGIGAGPGDGSLLTI
                     KAVNTLKKLDILYTPESKKGGDSLALSIVSEYLPESVEIKSRHFPMSFDGNEKSLAWD
                     NVAQEIISDVNDGKNVGFVTLGDPMIYSTYVYIMKRILGEVEVETIPGISSFSNIASN
                     QNFPLVMDKEALVVIPCTMEDDKIEYALQNYNSIVLMKVYKNFKEIIKKLEKYDLIEH
                     AILVSNSSQESENVFTDLKEAHLEDKISYFSTILVNKDNKIK"
     gene            17929..18834
                     /gene="hemC"
                     /locus_tag="ACGI5H_002760"
     CDS             17929..18834
                     /gene="hemC"
                     /locus_tag="ACGI5H_002760"
                     /EC_number="2.5.1.61"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891949.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004418 - hydroxymethylbilane synthase
                     activity [Evidence IEA];
                     GO_process: GO:0033014 - tetrapyrrole biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxymethylbilane synthase"
                     /protein_id="HFG9698457.1"
                     /translation="MNIVVGTRGSNLALIQTEWVINELKKKYPEISFEIKIIKTKGDL
                     IQNVSLDKIGDKGLFVKEIEQQLLDGKIDIAVHSMKDMPSYLADGLKFAHTPKREDPR
                     DVLILREGYKNLDDLPHGAVIGTGSKRRKFQLLKQRPDLNIVQVRGNVETRIRKIKDE
                     NMHGIVLAASGIIRANLQDKISSYLPVDVVIPAPAQGALAIEIRSNDSTIEGIVNSLK
                     DENTEIQILAERGFLDGVNGSCHIPMAAYCEIIQDKIHLTGLYGDSEGKKVVIKSIDG
                     DISSPRELGLKLAKLVLKEYENYEG"
     gene            18824..20323
                     /gene="cobA"
                     /locus_tag="ACGI5H_002761"
     CDS             18824..20323
                     /gene="cobA"
                     /locus_tag="ACGI5H_002761"
                     /EC_number="2.1.1.107"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891947.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004851 - uroporphyrin-III
                     C-methyltransferase activity [Evidence IEA];
                     GO_process: GO:0019354 - siroheme biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="uroporphyrinogen-III C-methyltransferase"
                     /protein_id="HFG9698458.1"
                     /translation="MKGKVYLVGAGPGDYKLMTLKGLECIRKSDVIVYDRLANSSYLR
                     EAKPDCELIYVGKASSNHILPQEDINRIIAEKAKEGKIVTRLKGGDPYVFGRGGEEAE
                     TLVDEGIEFEVVPGITSAIGGLCYAGIPITHRDHASSFHVITGHLKGDDSGELNWNAL
                     ANNKGTLVFLMGISNLEKISENLMKEGKDKDTPVALISWATRYNQRVVTSTLENVYET
                     AIKEEVKPPTLIVVGSVVGLREKLNFFESKPLFGKSIAVTRSRNQNSVLVEKIMDLGG
                     NPIEIPTIKVEKIQNNINLENEIKNINKYNYLILTSKNAVEIFFEKIYEMNFDLRILS
                     NLKVCAIGSATSNELKKRGIIADIVPKKFVAESLYEELAPILNDDDNILIPRAENARD
                     YLVDKLKAICEVTEVHIYRTVIDEEKKGEILDILNSNDIDYITFTSSSTVNNLVEIIG
                     KENIKILEKIKTLSIGPITTETINSLGIKLYKESATSTIDSLVDLIIKN"
     gene            20340..21305
                     /gene="hemB"
                     /locus_tag="ACGI5H_002762"
     CDS             20340..21305
                     /gene="hemB"
                     /locus_tag="ACGI5H_002762"
                     /EC_number="4.2.1.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891946.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003824 - catalytic activity [Evidence
                     IEA];
                     GO_function: GO:0004655 - porphobilinogen synthase
                     activity [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0033014 - tetrapyrrole biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="porphobilinogen synthase"
                     /protein_id="HFG9698459.1"
                     /translation="MLRRPRRLRASKAIRNLVRETKVNVEDLIYPLFVVEGENIKEEI
                     KSLPDVYHLSIDMLEDEIKEISELGIEHIMLFGVPDEKDECASQAFNDNGIVQKAIRK
                     VKEINSDINVITDVCMCQYTSHGHCGILTDTGYVDNDKSLEYLAKISVSHAKAGADMV
                     APSDMMDGRIQAIREALDENGLENVGIMAYSVKYASNYYGPFREAAHSAPSFGDRKTY
                     QMDPANSNEAIIETELDILEGADILMVKPALSYLDIIRRVKDNFDLPLAAYNVSGEYS
                     MLKFAVKEGLLNEDVILESITSIKRAGADIIITYFAKDIAKLLKK"
     gene            21458..22036
                     /locus_tag="ACGI5H_002763"
     CDS             21458..22036
                     /locus_tag="ACGI5H_002763"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425711.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional precorrin-2
                     dehydrogenase/sirohydrochlorin ferrochelatase"
                     /protein_id="HFG9698460.1"
                     /translation="MLYPINLKLDELDVVIIGGGEVAYRKCKNFLEFNKNVTIVSKQI
                     LNKFYDLKGNIKIIKDDYKEIYIKDASVIIAATNNRELNMEIGLYCKAKNKLVNVVDN
                     IEISNFTVPSYIKRGDLLISVSTGGKSPSLSSKIKKEIEERYTEDYEEYLNVLGDIRK
                     KVIKKYEDKSKRKDVLNMLVTLDLEELKKFDI"
BASE COUNT         9099 a         2125 c         4168 g         6734 t
ORIGIN      
        1 ttaaatttta tttgatatta tatttgaaag gtagatttta gtatattttg aaaattttgt
       61 tttgaaaatt tgggattatt taagaaattt tgtattataa atagaaggaa atagataaat
      121 tgtatagaat aaaatatatt aagataagtt aataatgtta aatgggaagt gagtttatgg
      181 aaaaaccaaa tacaaaagtt gttaactttc aagagtataa agacagaaaa aaccaaagag
      241 aagtaaatag agacgaactt ttaaagctta taaaaaaaat tgtgacttca aaatagggag
      301 ttgttaaact ccctatttta atgggtttca taataattaa gacattctaa gtccatctat
      361 ataatctttg aattgtgaga aatctgattc actacttaat tctatggttt ctgaaccttc
      421 cgtataaaaa ttcttaagat agatagtata attattatca acacaatcat gataaataca
      481 tctatatcca tcttcataca aactttttaa cttagaaaaa tcatccacaa tatcatctcc
      541 ttaaagttct tttaaatata tttttacaaa aagcatctaa ttgtatgcaa attgacaatg
      601 taaaataaag gaaatgaaca taaaatgtag aataattttt atatgtatgt aaaaataaaa
      661 agaaaaagtt gaaattttta gaaaataaga gtatttttta tctaaaaaga gagtttaaaa
      721 aataaaaaaa tgttgggagg ataaaaaatg agtttattag aaagtatatc aaaaaacata
      781 tattccctag ataactcttc tattgaaaaa acaaagcaga gattggatag gcttatacat
      841 ccaactggaa gcttaggaaa gatagaagat atttgcatgc aattagcagg aatatttggc
      901 aatgaaaatt ttgacacaag taaaaaggtt ataattgctt ttgcgggaga ccatggtgta
      961 tatgaagaag gcgtagcacc tgaccctcaa aatataacaa aattacagtt tccaaatttt
     1021 tcgaaaggtc tatgcggagt tggagtaata agtaaatttg taggggcaga tgttgtagct
     1081 gtagatgtag gaataaactg tgatgaaaaa ctggatgggg tattagacta caagataaga
     1141 aaagggacat caaatatggc aaaaggtcca gctatgagta aacaagaagc aattagatgt
     1201 ttagagatag gtattgaaat agcagagcag tgtatagaaa aagattataa ggttattggt
     1261 attggggaga tgggtatagc aaatactact ccaagtacag caataatatc tgtaatttca
     1321 gggtgtgacc cgttagaagt tactggtata ggtgcaggtc ttaagaaaga aagactaaag
     1381 cataaggctg aagtaattag aaaggctatt gaaattaata atccaaatcc aactgatgga
     1441 gtagatattt tatctaaagt aggagggttt gaaataggct caatggcagg tgttatatta
     1501 ggttgtagtg ctaataggat tccagtagta attgatgggt ttatttctta tgcagcagca
     1561 ttaattgcat ataagataaa tccaaaaact agagaatata tgatagcatc tcatttatca
     1621 gcagaatcag gaactaaaag agcattagac atattaaaat tagaccctct attaaatatg
     1681 gatatgagat taggtgaggg aagtggagct gctttagcat ttgatataat agaagcttca
     1741 aactatactt ataaaaatat ggcaactttt gatgaaattg acatgggaag ataaatataa
     1801 aaatttaata tgtaggagtg ttttgatgag taaaattatt ctagtaacag gaggagctag
     1861 gtcagggaag agtaactttg cagaaaaact atgttttgac agaaataata atacagctta
     1921 tatagcaacc tctattccat ttgatgatga aatgaaagat agagtaaaaa aacatcaaga
     1981 gaatagacct agaaactgga atacttatga aatatatgaa gatatatatt ccataattaa
     2041 ggagatatat aaagaacatg aaactgttat actagattgt gtaacattat tagtaaataa
     2101 tctaatgttt gaacacaatc taaatataga agaatctagt caagaagaaa taaacaaatt
     2161 agaacaatac ataaaagaac aagttgtcaa acttattgaa gaaatagaaa aaacaaatct
     2221 atactttgta tttgtaacga atgagttagg tatgggaatt gttcctggga ataaacttag
     2281 tagaatttat gctgatattg taggtcgtat aaatcaatat atagcttcga aaagtaatga
     2341 agtttatttt gtagttagtg gcatagctat gaagataaag gagtagtatg caattatgaa
     2401 aagatttatt ttaatactac agtttttgac aaggatacct ataaaattaa atgtaggatt
     2461 tgatgatgaa ttttataagt caatagtata ttttccactt gtaggttttg tcataggtat
     2521 attatcctat ttaataggat ggatttctat gcttttattt gaaccattta tagcttctat
     2581 aataataact ctagctggtg tcttaattac tggaggactt catatagatg gattaggaga
     2641 tacatttgat gcaatatata gttataggga taaagaaaag atgcttgaaa taatgaaaga
     2701 ttcaagatta ggtacaaatt cacttctagc aattatgttt gtacttttat taaaggttgg
     2761 attcgtttac gatataataa gtaataattc attgtgggtt ataattttta tgccaatgat
     2821 tgcaaggtta ggagtaatgt tattgacata taaaactgtg acaccaagag aaaaaggaat
     2881 gggaaattta tttataggaa aattaactac aagtatgtta ataactgcta taatatacac
     2941 attattgata gttgctctta ttactaaatt tatattttta ttacctaata tagtgttgat
     3001 taaagtatta ggttcgatta tagtggtttt tgtatttata atattattca aaaaacatat
     3061 ttataaaaaa attgacggag taacaggaga tatattaggc tgtggaatag aactttcaga
     3121 gcttgtatat ttaatttaca tatatttgtt aatttttatg tttttttaaa gtaaaaagtg
     3181 gtgataatat gataagatta atattaataa gacatgcact gacaaatgat aataaaaaag
     3241 gaagattatc aggccatata aatagttgta ttagtgaaga gggcaaacta caaataaata
     3301 aaattaccag atatctgagt aatgaaaaca tagataaggt ttatacaaca ccatctacac
     3361 gtactaaaga tacagtagaa aaaatatcaa aattgaaatt attagaaata gaagaaaaag
     3421 aagctttaag agaaattagt tttggagact ttgaaggaag aacttttgaa gaaattaaaa
     3481 tcaaatatcc aaatgagttt gaaaaaatga taaaagaagg taacaactat agatatccaa
     3541 atggagaaag tttgatagac tcttataaaa gagtggcaaa agaaattgat aatataattt
     3601 tagaaaataa tagtaattta gatacaaaga caatacttat atgttctcat gcaggaacaa
     3661 taagaaatat aataacacat ttgatttctg gtagttataa gtatcactgg aactttaaaa
     3721 ttgataatgc atctattaca gttttagaaa ttgatggtgg atttgctgta atagataaaa
     3781 tgaattttac agacttcata taatttaatc aaaaccaaac attacaatct gtgtttgtaa
     3841 tatatctgta aaattagcaa tgaaaataga atattagatt aaaattaggt tcttaattag
     3901 atgttaaaag ggaaaaaggt tagatgcctt tgcagccccc gctactgtga aaccaacgaa
     3961 actataaata ccactgtcag tttgatggga aggttataga agtaggatga agttaagcca
     4021 ggatacctgc ctaatttaat ttaaaacaag aggtcttcgg ggtgaaagat ttttaattaa
     4081 tatatataaa agtcctatct ttagaagtat taggactttt tttaatttgt tttttagtaa
     4141 attttaacaa ggagggatgg aaagtgggga aaaaaataat gctacaagga acagcttcaa
     4201 atgtaggtaa aagtgtctta gtagcaggtt tgtgtagaat atttaagcaa gatggttata
     4261 ctgttgctcc ttttaagtca caaaatatgg ctttaaattc ttttataact aaagaaggat
     4321 tagaaatggg aagagcacaa gtatttcaag cagaggctgc gaaaatagag ccaatagctg
     4381 atatgaatcc agttttatta aaaccttctg gaaataataa aagtcaagtt attgtaagag
     4441 gtaaagttgt aggagaaatg ccttcttcta agtatcatga ttataaattg gagttagtag
     4501 atgtgttgaa ggaaacattt aatagcttaa attcaaggta tgatattgta gttatggaag
     4561 gggcaggaag taatgcagag ataaacttaa aagatagaga tatctctaat atgggtatgg
     4621 cagaaatagc tgatgcacct gtaataatag tcggagatat tgatagagga ggcgtatttg
     4681 cctcattagc aggaacaatg cttttattaa atgaagatga gaaaagaaga gtaaaaggtg
     4741 taataatcaa taaattcaga ggaaaaaaag agcttttaca agatggtgta aagatgctag
     4801 aagacatcat aaaagtacct gttataggag tagtacctta tacagatata aaaatagaag
     4861 atgaagacag tgtaactacg agatttaaga aaaaaatgaa taaaagtgat atacacatag
     4921 aaataattag aaccccacat atgtcaaatt ttacagattt taatatattt gagacacaag
     4981 aagatgtaag tataagatat gtagactatg gagaatcttt aggaaatcca gatatattaa
     5041 taatacctgg aactaaaagt actatagacg atttaacata tataagaaaa agtggtcttg
     5101 aatcgcaaat caaaaattta catagtcaag gtaaattgat atttgggata tgtggtggat
     5161 accaaatgtt aggtaaaaaa ttaaaagacc cttatcatgt tgaaagtgaa attgaagaag
     5221 ttgatggaat aggtctttta gatacagaaa caacgtttga gaaagaaaag actacaacac
     5281 aagtagaagc tactattgtt gaatgtatca gtgaatacat gaataacctt aagggaaaaa
     5341 aagtaaaagg ttatgaaatt catatgggaa ttacaaagcg aggtaatgat gtaagaagtt
     5401 tagatttaat aactaaaaaa cttgataaag aagtgaatta tactgaggga agtgtaaata
     5461 aagaggggaa tgtaattggg acttatcttc atggaatatt tgatgaaata agctttacaa
     5521 gagcaatttt aaacaatata agaaagaaaa aaggtttagg agaattagaa agcaaagtaa
     5581 actcttttaa tgaatttaag gataaagagt atgataagtt ggctgatttt ttaagagaac
     5641 atttagatat agagaaaata tatgagatta tgaaataatg atgaccttta tttataattt
     5701 aggtaggagg tgtattatga aaaaaatttt aattgcgggt actaatagtg gagtaggtaa
     5761 aacaacaata tcattaggaa taatgcaagc tttggttaag agaaatatga aagtacagcc
     5821 atataaagta gggccagact atatagaccc ttcatatcac acttttataa ctggaagaca
     5881 ttctagaaat ttagattctt atatgttaga tgatgaaaaa ataaagtata tagtaaataa
     5941 gtcctcaaaa gatgcagata tttcagtaat agaaggtgtt atgggcttat atgatggctt
     6001 tggaatagat ttagataatt gtacaagttc acatacttca aaggtattaa agtcacctgt
     6061 tatattagtt ataaatggta aatctatggc agcatctagt gctgctatgg tacttggata
     6121 taaggaacta gataaagatg taaatataaa gggtgttata gtaaataatg taaagactaa
     6181 tagccattat caaataatta agagttctat agaaaaatat tgtaatgttg aagtattggg
     6241 gtattttcct ccaaataaca aattctcttt ggaatctcga catctaggat tagttcctag
     6301 tgtagaaatg aaatcactaa gggaaaaatt ttatacctta gcagatgaaa ttgaacacta
     6361 tatagatatt gacagaataa ttgaaatatc agaaagtgat gaatttgaga gtgattttga
     6421 ttttcaaact ttgatagaaa ataataaaat aaaagaacat gttaataata aatcaatagc
     6481 tatagcatat gataaagcat tcaattttta ttatagagaa aatatagagc ttttagagga
     6541 acttggttta gaaataaact attttagccc tcttgaagat gtatcagtgc caaatgcaga
     6601 ttatatttat attggaggag gttttccaga aatatttgga aaagaattag aagcaaatga
     6661 gtcaatgaga acttccatat tagaagcaca taacaataat atacctattt atgcagaatg
     6721 tggaggactg atgtacctag gtgagaaact attgaatcaa gaagaacaag aatttaatat
     6781 ggttggaata tttagtggaa ttagtaagat gacatcttct ttaaagagat ttgggtactg
     6841 tattggtgta gccaaggaaa atactctttt atctaaaaaa ggggaatcca ttaaagggca
     6901 tgagtttcat cattcaatat ttgaaagtga tgaaaaatgt gtatattcaa tgagaaaaga
     6961 aagagatgga aatatagtag aagagtggga tggtggttat agtaaaggaa acactttggc
     7021 tacatatctt catactcatt tttataataa cttaaattgt atagaaaatt ttttgaaaaa
     7081 aggaaatgaa taaatgagta ttttatctat ttatatagga tatgtgacag acttaattgt
     7141 aggagaccca tattcttttc ctcatccagt gagatttatt ggtaaactta taaattttac
     7201 tcaaggtata ataagaaagg tctctaaaaa tgataggcag ttaaaatttg ggggatttat
     7261 attatggttt ataaccgttg gaataacata tttaacaact tatgctatag tgaagttatt
     7321 tagttttaat atattattga gtattgtagt gaatagtttt ataatttata caacactagc
     7381 cacaaaatgt ttaaaagacg aagcattaaa aatttataat gtattaaaaa ctgaagatat
     7441 agaaaaatct aggattcagc tatcttatat agtaggtagg gatactacta atttaagtga
     7501 acctgaaata ataagagcaa ctgtagaaac tgttgcagaa aatactgtag atggtataat
     7561 tgcgcctatg ttttatgcat ttattggagg agcaccactt gctatggcct ataaagctat
     7621 caatacattg gactcaacag ttggatataa aaataaaaag tataaagata ttggttttgc
     7681 atctgctaag attgatgata tagccaatta tataccagct agaatatctg tcattcttat
     7741 gacaattgga agtttctttt taaattataa ctataggaac tgttttaaaa tctctattag
     7801 agatagaaag aatcataaaa gtccaaattg tgctttttca gaaggtgcag tatctggtgc
     7861 tctaggaata caactaggag gtaccaacgt ttattttggg gaaaaagtat ataagccaac
     7921 aataggggat aagcttaggg agatagataa agaagatata attaaaacta ataaaattat
     7981 gtatgcatct tcatttgtat ctatgttggt atttacacta atatatgtgt tatgtaggat
     8041 gattttaatt aacttaatta tataaattat tgtttgttaa cttaaggggg acatagatga
     8101 aggatttagg gcatggtgcc aatgtagatg aaatggcaag attatatggg aaaaacccaa
     8161 aagaaataat tgattttagt tcaaacataa atccaaatgt attaccaaat ttagagagat
     8221 acattttaaa aggattagaa gagtgtagga attatccaga tataaattat acaaacttga
     8281 gagaaaatat atcaaaatat atagatataa atccagactt tataatacct ggcaatggtg
     8341 caacagaagt gatttatttg cttatgaaga gtattaaaaa aaaattggct ataataaatc
     8401 cgactttttc agagtataga agaagtgctg agttaaataa tttagatatt atagatttag
     8461 agttagattt agaaaataac tttaaactta atatagatat aataaaagaa aatataaaaa
     8521 gatttgatag tttatttata tgtaatccta ataatccgag tggtaatgtc caagatttaa
     8581 aggaacttgt tcatttacta gataaacata ataaggtact aataattgat gaaactttca
     8641 tggaatttgt tgaagatgaa agtaaatata gtttggttaa atatatagaa tcaaataaaa
     8701 atatatttat aattaaagct gtgactaagt tttttggtat gcctggttta aggctaggat
     8761 atggtcttac aagcaacact gaaattatga acaaaattta tgaacacaaa gagccatgga
     8821 ctatcaattc ttttgcagat atactatcca attttatttt tgaagataaa gagtatatta
     8881 aaaatagtaa agaatattac atagaagaaa gaaaatatat gttacaagag ttgagaaaca
     8941 taagaaatat aaaggtctat gatacagatg ctaattttat cttgataaga atatataaaa
     9001 aaacaactaa agaattgaaa aaagatttgt ttaagcaagg aaacatatta gttagagatg
     9061 catctaattt tataggatta gatgatagct ttataagagt ggctataaaa tctcatgaag
     9121 ataacaaaat tcttatagaa aatatgaaaa atttattggg tgattaaaat gaaatcttat
     9181 ggaatatgcc cagcatcttg tggagaattt gtacaaggta taattgatga tgaagaatat
     9241 ttatgttcat atgcaataga tatgtattct aaagtgtata ttgaagaaaa attagtagat
     9301 ataaatttag ggagatataa gtcaaggtta gcaattgaaa aggtatttga aaaatttaat
     9361 ctacctaaaa aatatactaa aaatatttct ttaaatataa atagtaaaat acctgttgga
     9421 aaaggaatgg caagttcaac tgctgatata ggagctacta taaaggcaac attatcattg
     9481 atagataaag atttaagtag cgaggagatt tctaaattag cagcagaaat agaaccaaca
     9541 gattctatat ttatagataa aaatagtata tttaatcctc taaatggaac tgttataaaa
     9601 tacctaggaa atctgaccaa tgcgaaagtt gtaatacttg aaccaaacaa agtactagat
     9661 actatgaaaa ttagattgag gcaagattat aataaattaa aagtagagaa taaagaagta
     9721 ataaaaaaat catttgctct tttagaagaa ggattgaaaa aaaataattt atctctagtt
     9781 ggagaggctt gtactttgag tagcttagca aatgagaata tagaaaaaaa agagtattta
     9841 aatgaaataa taaaaatatc aaaaaaatat ggagcatatg gagtaaatat tgctcacagt
     9901 ggaactgtag taggtatttt aattgataag tttatgaatg ataaaaagat gatagatgcc
     9961 ttatgtgaat ctaacataaa ttctgtctat aataaaattt atacacaaaa cataattaat
    10021 ggaggaatta agggggaaat agaatggaat acataaagaa tcctatgaaa atagaagaaa
    10081 aaagttttga attgatacaa gaaataatag acgaaattag accagattat aaatttaaga
    10141 ataatatcga agaaaaaata ataaaaagag ctatacatac tactgctgat tttgattact
    10201 tagatatatt aaaaatatca gaagaagcag ttgatagtat aatagatgca ttaaaaaata
    10261 atgcaagtat ttatactgat acaaatatgg ctcttagtgg tataaataaa agaaagttag
    10321 aatcattagg atgtaagtat aaatgtttag tggcagatga tgaaactgta aaattagcta
    10381 aagaaaaagg aattactcgt tctatggcag cagtagaaat tgcagctaaa gaagaaggaa
    10441 gaaaaatatt cgttttaggt aatgctccaa cagctttata taaagttatg gagatgaaat
    10501 cagaaggtag attagattta gatgcagtta taggagttcc tgtaggtttt gtaggagcac
    10561 aagaatcaaa agatgaagtt gaaaaaacag atataccata tataatttct aaaggtagaa
    10621 aaggtggcag taatttagca gcagcaatag taaatgctat attatatact atgtaggtac
    10681 ctatatggaa gaatatgtat atatagatgg aaaaaaatat agaagaggat atactacagg
    10741 ttcatgtgca acaggtgcat ctaaggctgc tgtatatatg ttgattacaa aaaatagaat
    10801 caatactata aatatagata ctcctaaggg gataccatta ctactaaaag ttgataatat
    10861 aaatatttct gatacatttg tggaatgttc cataaaaaaa gatggtggag atgatataga
    10921 tgcaactcat accatggata tttatgcaag agctgaaatt gtagctaaaa atgataagaa
    10981 caaagggtat cttactctaa aggatataga taatttaagc accaatagtg agtgtaaaag
    11041 tgagctctat aagtttatta gggtttatgg cggaactggt attggtgtgg ttacaaaaaa
    11101 aggtcttagc gtggatgttg gtaaacctgc tataaatccg actccactta aaatgataaa
    11161 tcatgaaata agaaagctta taggagataa ttttgaatct atacttggaa atgataaagt
    11221 tttaaaaata acaatctttg ctccacaagg agaaactgta gcaaaaaaaa catttaatcc
    11281 aagattaggt atagttggag gaatatctat aataggtaca actgggattg ttgaacctat
    11341 gagtgatgag ggttggaaga agtctctatc tatagaactt cagatgaaaa aagaacaagg
    11401 cttagataaa ataatattgg ttccaggaaa tcatggagaa cagtttataa gagaaaaatt
    11461 aaacttagat attaagtatg tagttagggt aagtaatttt ataggctata tgattaaaga
    11521 agctcaaaga ataggatata agaaaatctt aatggcaggt catataggta aatttataaa
    11581 agtatctgct ggtattttta atactcatag taaggtagca gatgctagaa gtgagatatt
    11641 agtggcaaac ttagctttaa tgggagctag atacgaattt ttaaataaaa taaatcaatg
    11701 cgtaactact gaagaagctg tagagctaat aaataatagt gaatatagag aagtatataa
    11761 tatattaagt aataaatgta gggagagagt aaagcaatac ttgaatgaag attcagatga
    11821 tattgatgtg gaagtaatca tattttcaat ggataagtct ttattaggta aatcggataa
    11881 tacagatgat ttagtggagg tctttatatg ataaacataa taggtctagg acctggtaac
    11941 ttagactata taacaaaaaa aggtgaaaat ttaatttcca cttctgatgt attaattggt
    12001 ggtaaaagaa atttagagtc tataaaaaat tttgaaggag aaaaaatagt tctggattct
    12061 aatttaagag aaattataga gtacataaat aacaataaag aaaagcaaat atcaataata
    12121 gcatctgggg acccactaat atatgggata ggtagatatc tatctaaaaa tattgataat
    12181 aagatgttaa acatggtttc tgggattagt tcattacagt acatattttc aaaaatatat
    12241 gtagatatga atgatgtata tattacaagt agtcatggta aagtaccaga ttttgattac
    12301 atattatcac ataaaaaagt atgtatggtt acagattcaa agataggacc aaaacaaata
    12361 agtagagaaa taatagatag aaatctaaat aaaattattg ttgtaggaga aaatctgtca
    12421 tatgacaatg aaaaaataac aatagcaaaa ccagaagaga taataagaat ggacaatttt
    12481 gatatgaatg ttgtggtgat tttagatgag gaatagtgaa tttataacag gtaaagttcc
    12541 aattactaag gaagaggtta gagcaatatc aataagtaag ttaaatttag taaatgctaa
    12601 aaacctcata gacatagggg ctggtacagg aagtgtaagt gttgaagctg catataatta
    12661 tcctaattta aaggttatat ctatagagaa aaatgatgat gctatagagc ttatagagaa
    12721 aaataaaaaa aaattcaact tgaaaaatat agaagtgata aaaggatatg ctccaattaa
    12781 tctagggtta aatgttaaag ttgagtctat ttttcttggg ggaacaggaa ataatctgga
    12841 agaaataata gaatggtcta aaaaaaatct cgttacagga ggaagacttg tagctaattt
    12901 tataataata gatacattta atcaaacttt aaaactgctt aaaaagcatg gatttaaaga
    12961 aatagatgta tgtgttttga atgtttctaa actagagaaa ctaggaaaag gtgaatattt
    13021 taaaccacta aatcctatat atataatatc ttgtgaaaaa ggggaaaatg atgatgaata
    13081 aagtacattt tgtaggagca ggacctggag ataaagagct gataacatta aaaggataca
    13141 aattattaag taatgcagat gtagtgatat atgcaggttc acttgttaat cctgaacttt
    13201 tggaatactg taaagaagat tgccaaatac ataatagtgc acatatggat ttacaagaga
    13261 taatagatgt tatgagagaa ggtatagaaa ataataaatc tgttgtaaga ctgcaaacag
    13321 gtgatttttc tatatatggt tcaattagag aacaagtgga agatttaaat aaattgaata
    13381 tagattatga ctgtactcct ggagtaagtt cttttttagg ggcagcatca tctttagggg
    13441 ttgaatatac agttccagaa atttctcaaa gtgtaattat aacaagaatg gaaggcagaa
    13501 ctccggttcc agagaaagaa tcaatacaat catatgctaa gcatcagaca tctatggtaa
    13561 tatttttatc tgttcaagaa attgagaaag ttgtgtctaa attactggaa ggtggatatc
    13621 caaaagatac tcctatagca gttatataca aagcaacttg ggcagatgaa aaaatagtta
    13681 aaggaacttt aagtgatata gctgtaaaag ttaaagaaaa caacataaat aagactgctt
    13741 taataatggt tgggagattt ttaggagaag agtataataa ttcaaagtta tatgataagg
    13801 atttcaaaca tgaatataga gggtaatatt gctataatct gtattacaga aaatggaaaa
    13861 aaattagctc taaagataaa ttctctagta aataactgtg ttatatatca agtaaaaaat
    13921 aaaaaaagta atttagttgt tgaagaaaca tgtgtgcata cagttcaaaa gaagttaagt
    13981 gattttgtag gagaaatatt tagcaaattt gattacatag tatttataat ggctacaggt
    14041 atagttgtac gaagtatagc accatacata ataagtaagt ttagtgaccc tgcaattttg
    14101 gtaatggatg aaaaaggcaa aaacgtaata agtttattga gtggtcatat tggaggggca
    14161 aacagcttga cacagtacat aagtagtctt attgatgcta atccagtaat aacaacagct
    14221 actgatataa atcaaaaagc ttccttagat atgatagcaa aaaaactaaa tgcacatatt
    14281 gataatttta gagaaagtgt aaaagaagta aattctatgc tagtgaataa taaatgtgtt
    14341 ggattatatg ttgatgaagg atatcaagtt gatactaggg gatttaaact tatagaaagt
    14401 aaggatgagt taagagatag tttttcaaac acatatatag aaaaattagt tgtagtaagc
    14461 aataaaataa attgtattga agatattgag aatttaaacc tagataataa atttgaacat
    14521 tgctatagta cccaaaaaat aataaaggta attccaagag atatagtgat aggaattggc
    14581 tgtagaagaa acacagatag tgaactgatg tataattcac ttgaagagtt tcttaataaa
    14641 caaaatatag atattagagc aataaacaca gttggaagta tagaactgaa aaaagacgaa
    14701 aaagcaataa ttgaattatc aaaaatattg aaggtgccat ttaaaacatt ttcagtagat
    14761 gaaatatcta aggttgataa tctttttgat aaatctgatt ttgttaaaaa aaatgtgggt
    14821 gtgtattcag tagcagaacc tgtagcatat cttttgagca aaggtaattt gttagttgaa
    14881 aaacataaat ataaaggaat aactttttca gtggggagaa taaaaatatg atatacgttg
    14941 taggaattgg accaggaagt aaagatacaa tgactttaga agcaataaaa gcaatagaag
    15001 attctgaggc tattgttgga tataagactt atataaaact aatagaagaa tttatacaag
    15061 gtaaagaaat aatccaaaat ggtatgaggc aagaagttga tagatgtaaa caagcagtgg
    15121 aggaagcaaa aaaaggaaaa aaagtagcag ttgtaagcag tggtgatgct ggaatatatg
    15181 ggatggcagg tcttatttta gaattaatat ctaaagaaga tgaagatata aaagtaaagg
    15241 taattccagg cgttactgca agtattggtg cagcagctat acttggagct cctattatgc
    15301 atgatttctg tcatataagt ttgagtgatt taatgactcc gtgggaagta attgaaaaaa
    15361 gattgagatt ggctgctgaa gccgattttg taatttgttt gtataatcca agaagtaagg
    15421 gaagaagtga acatctaagc aaagcattca aaataatggg tgagtttaaa ggtggagata
    15481 cacctgttgg agtggtaaaa gatgtaggta gagaaaaaga agaaaagttt gtatgtactt
    15541 ttgaaaatat ggactttgaa aaagtcgata tgactacaat ggttataata ggaaataagt
    15601 ctacctatat taatggtgaa ttgatgataa ctccaagagg ttatacagta tgattttaat
    15661 tttaggagga acttcagata gtttatctat atgtgataag ataaatgaac tgaaaaatca
    15721 accatatatc ctttcagtta ctacagatta tggaagggaa cttgcacaac aacatgcaga
    15781 gaatgtaatt ttaggtaagc ttggaaaaga agatatgcta aaatttataa aagataataa
    15841 tatagtaaaa ataatagatg ccactcatcc ttatgcagtt gaagtatcca aaactgctat
    15901 tacttgtgca aaactattga atatagatta tataaggttt gagagaaaat ctttaattga
    15961 agaaatagat tatgataata aatttatagt agatacaatt gaagaagcct gtgaaatagc
    16021 aaataaaata gggacaaata tattcatagg aacaggaagt aaaaatttga acagatttat
    16081 agaggaaata agtgataaaa atttagttgt tagagttctt ccaacgagtg aagtcatatt
    16141 aagttgtgaa aaattaggtt taagtgcaga taatatagta gctatgaaag gtccatttag
    16201 ccagtatata aatgaagaaa catataaaca ttacaatata gatttagtca taacaaaaga
    16261 aagtggaata gctggtgggt tcttagagaa ggtaaatgca tgtaaaactt tcaatatacc
    16321 agtaataatt ataaaaagag aatcgattaa ctacgaaaat gtatttaatg acataaataa
    16381 aattaaagac atacttgtgt aatttttagg aggagaatat atgaagaaag ccttattagt
    16441 agtgagtttt ggtacaagct atcatgaaac gagagaaaag acaatagata tatgtgaaga
    16501 taaaataaaa aattcgttaa aaagccatga tttttttaga gcttatacat caaatatgat
    16561 aataaataaa ataaaaaaaa gggatggaat agaaatagat aatccaatac aggctttaga
    16621 taaaatatat gaacaaggat atgatgaagt aataatccaa acacttcata ttatatgtgg
    16681 cgaagaattt aacaaattaa aagaacaagt agatggatat tcttctaaat tcaaaaagat
    16741 tgtattagga agacctttgc ttacacatat tgaagattat caggaagctg tagaggcaat
    16801 taagcatcaa attcctcata tggaaagtaa tgaagcagta gtatttatgg gacatggaac
    16861 acttcatgaa tcacattcag cgtatccagc attggaatac atgcttaggg ataatggaat
    16921 aaatgcttat gttggtacag ttgaagggta tccagaaata gaacatgtaa taagaagatt
    16981 aaaagaagga aatataaaaa ctgtaaattt gatgccattt atgttagttg caggagacca
    17041 tgctataaat gatatggcag gagatgaaga agattcttgg aaaacaatat tagaagaaaa
    17101 tggatttaac gtaagagttc atttaaaagg actaggagaa aattcttata tacaagataa
    17161 atttgttcgt catgctgtaa aatgtgcaga gaatgcgaag ttctatggta taggagcagg
    17221 gccaggagat ggttctttac ttacgataaa agcggttaat actttaaaga aactggatat
    17281 tctatacact ccagaatcaa aaaagggtgg agatagtcta gctttatcaa tagttagtga
    17341 atatttacct gaatcagtgg aaataaagtc taggcatttc ccaatgagtt ttgatgggaa
    17401 tgaaaaaagt ttagcttggg acaatgtggc acaagaaatt atatcagatg ttaatgatgg
    17461 taaaaatgta ggatttgtta cattaggaga ccctatgatt tatagtacat atgtatatat
    17521 aatgaaaaga atattaggag aggtagaagt cgaaactata ccaggaattt catcattttc
    17581 caatatagca tctaatcaga attttccatt agtcatggat aaagaagctt tagtggtaat
    17641 tccttgtact atggaagatg ataagataga gtatgctttg caaaattata attcaatagt
    17701 attgatgaaa gtatataaaa attttaaaga aataataaaa aaattagaaa agtatgattt
    17761 aatagaacat gctattttag taagtaattc ttcccaagaa agcgaaaatg tgtttacaga
    17821 tttaaaagaa gcgcaccttg aagataagat atcttatttt tctactatac tagtaaataa
    17881 agataataaa ataaaatagg tgaaagcaat atttaaagga gacttaatat gaatatagtg
    17941 gttggaacta ggggtagtaa tctagcgctt atacaaacag aatgggtaat aaatgaatta
    18001 aaaaagaagt atccagaaat tagttttgag attaaaatca taaagacaaa aggagattta
    18061 attcaaaatg tttcactgga taaaataggt gataaaggat tgtttgtcaa agaaatagag
    18121 caacaattat tagatggaaa aatagacata gcagtacata gtatgaaaga tatgccttct
    18181 tatttagcag atggactaaa atttgctcat acgcctaaga gagaagaccc aagagatgtt
    18241 ctaatactta gagaaggata taaaaattta gatgatttgc ctcatggagc agtaatagga
    18301 acaggaagta aaagaaggaa gtttcaatta ttgaaacaaa gacctgattt aaatatagta
    18361 caagttagag gtaatgtgga aactaggata cgaaaaataa aagatgaaaa catgcatggt
    18421 attgtgttgg cagcatcagg aataattaga gctaatttac aagataaaat aagttcttat
    18481 ttacctgttg atgttgttat tccagcacct gcccaaggag ctttagctat agaaattaga
    18541 agcaatgata gtacgataga gggaatagta aattcactga aggatgagaa tacagaaatc
    18601 caaatattgg ctgaaagagg ttttttagat ggtgtaaatg gaagttgtca tattccaatg
    18661 gcagcttatt gtgaaataat ccaagataaa atacatctta ctggcttata tggagattca
    18721 gaaggaaaaa aagtagtaat caagtctata gatggagata tttcttctcc tagagagtta
    18781 ggtttaaagt tagctaaact tgtattgaag gagtatgaga attatgaagg gtaaggttta
    18841 cttagtaggg gcaggaccag gtgattataa actcatgact ttaaaaggtt tagagtgtat
    18901 aagaaaatcg gatgtaatag tatatgatag attagcaaat agtagttatt taagagaagc
    18961 taagcctgat tgtgaactta tatatgtagg caaggcatca agtaatcata ttttgccaca
    19021 agaagatata aatagaatta tagcagaaaa agctaaagaa ggaaaaattg taactcgtct
    19081 taaaggagga gacccttatg tatttggcag agggggagaa gaagcagaga ctttagtaga
    19141 tgaaggtata gaatttgaag tagttccagg tataacttct gctataggag gtttatgtta
    19201 tgcgggtatt cctataacac atagagacca tgcttcgtca tttcatgtaa taacaggtca
    19261 tttgaagggt gatgatagtg gagaattaaa ctggaatgct cttgcaaata acaaaggtac
    19321 tcttgtgttt ttgatgggaa tttcaaacct agagaaaata agtgaaaact taatgaaaga
    19381 aggaaaagat aaggatacac ctgttgctct tataagttgg gcaactagat ataatcaaag
    19441 agttgttaca tctacacttg aaaatgttta tgaaactgct attaaagaag aagtaaaacc
    19501 gccaactctt atagtagttg ggagtgttgt aggacttaga gaaaagttga acttctttga
    19561 aagtaagcct ttatttggaa aaagtattgc tgtaactagg tctagaaatc aaaatagtgt
    19621 attggtagaa aaaataatgg atttaggtgg aaatcctata gaaataccta ctattaaggt
    19681 agaaaaaata caaaataata ttaacttaga aaatgaaata aaaaatataa ataagtataa
    19741 ttatctaata ctaactagta aaaatgccgt agaaatcttc tttgaaaaga tatatgaaat
    19801 gaattttgat ttaaggatat tatctaattt aaaggtatgt gctataggtt ctgctacatc
    19861 aaatgagttg aaaaaaagag gaattatagc ggatatagta ccaaaaaaat ttgtagcaga
    19921 gtcactgtat gaagagttag cgcctatttt aaatgatgac gataatatac ttatacctag
    19981 agcagaaaat gctagagatt atctggttga caaactcaag gctatttgtg aagtaacaga
    20041 agtacatata tatagaacag taatagatga ggagaaaaaa ggtgagatat tagatatttt
    20101 aaattctaat gacatagatt atataacatt tactagttcc tcaacagtaa ataatcttgt
    20161 tgaaattata ggaaaagaaa atattaaaat attagaaaaa ataaaaacac tatctatagg
    20221 tcctataact acagagacaa taaatagttt gggaataaaa ttgtacaaag aatctgctac
    20281 atctactata gattcgttag tagatttaat tataaaaaat taattttgga ggcttgaata
    20341 tgttaagaag accaagaaga ctaagagcaa gtaaagcaat cagaaatttg gtaagagaaa
    20401 ctaaggtgaa tgtagaagac ttaatatatc cactgtttgt agtagagggg gaaaatataa
    20461 aagaagaaat taaatcttta ccagatgtct atcatttatc aatagatatg ctagaagacg
    20521 aaataaaaga aataagtgag ttgggaattg aacatataat gttatttggt gttccagatg
    20581 aaaaagatga gtgtgcttca caagctttta atgataatgg aatagttcaa aaggcaatta
    20641 gaaaggtaaa agaaataaat tcagatataa atgtaataac agatgtctgt atgtgccaat
    20701 atacaagtca tggacattgt gggattttaa ctgatactgg ttatgttgat aatgataaat
    20761 cattggagta tttggctaaa atatctgtaa gccatgctaa agcaggagct gatatggttg
    20821 ctccatctga tatgatggat ggaagaatac aagcaataag agaagcttta gatgaaaatg
    20881 gattagaaaa tgttggaatc atggcttata gtgttaagta tgcttcaaat tattatggac
    20941 cttttagaga ggcagctcat tcagcaccat cttttggaga tagaaaaaca tatcaaatgg
    21001 acccagcaaa tagcaatgaa gctataatag agactgaact tgatatattg gaaggtgcag
    21061 atatacttat ggttaaacct gcattatcat atttagatat tataagaaga gttaaagata
    21121 attttgactt acctctagca gcttataatg taagtggaga atactctatg cttaagtttg
    21181 ctgtgaagga aggtttatta aatgaagatg taattcttga atcaattaca tctataaaaa
    21241 gagcaggagc agatataata ataacttatt ttgctaaaga cattgctaaa ctgttgaaaa
    21301 aataaattct agcagtataa agaatatcaa aaagtatagg aattgtaatt aactattata
    21361 cagtagtttt gtttagacat ttattgaaga ataatagaaa ctaatttgca atttctatac
    21421 tttatttatg taactaaata aaatttggag gtagaagatg ctatatccta ttaatttaaa
    21481 attagatgag ttagatgtag ttataattgg tggtggagaa gttgcatata ggaaatgtaa
    21541 aaatttttta gagtttaaca aaaatgttac tatagtttct aaacaaattt taaataaatt
    21601 ttatgattta aaaggaaata taaaaataat aaaagatgat tataaagaaa tatatataaa
    21661 agatgcttct gtaataattg ctgccacaaa taatagagag ttaaatatgg aaataggatt
    21721 atattgtaaa gcaaaaaata agctagtgaa tgtagttgat aatatagaaa tatcgaactt
    21781 tactgttcca tcatatataa aaagaggaga tttacttata agtgtgtcta ctgggggcaa
    21841 gagtccttca ttatcatcaa agataaaaaa agaaattgaa gagagatata ctgaagatta
    21901 tgaggagtat ttaaatgtat taggagatat aagaaaaaag gttataaaaa aatacgaaga
    21961 taaaagtaaa agaaaagatg tgcttaatat gttggtaaca cttgacctag aagaacttaa
    22021 gaagtttgat atataaaaaa taaaataaaa aatgttaaaa aggtgttgac ggattatttt
    22081 taagatgata tagtattact tgtccttaag aaaagggcaa acataa
//
LOCUS       DAYAOO010000068        21750 bp    DNA     linear   BCT 12-OCT-2024
DEFINITION  TPA_asm: Clostridioides difficile isolate ST8-SSI-h139-18
            SAMN40601845-rid21577343.denovo.068, whole genome shotgun sequence.
ACCESSION   DAYAOO010000068 DAYAOO010000000
VERSION     DAYAOO010000068.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN40601845
            Sequence Read Archive: SRR28438827
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 21750)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 21750)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-MAY-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-MAY-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002157583.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002157583.1
            Genome Coverage       :: 163x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/11/2024 16:19:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 4,038
            CDSs (total)                      :: 3,963
            Genes (coding)                    :: 3,930
            CDSs (with protein)               :: 3,930
            Genes (RNA)                       :: 75
            rRNAs                             :: 6, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 60
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 33
            CDSs (without protein)            :: 33
            Pseudo Genes (ambiguous residues) :: 0 of 33
            Pseudo Genes (frameshifted)       :: 7 of 33
            Pseudo Genes (incomplete)         :: 25 of 33
            Pseudo Genes (internal stop)      :: 11 of 33
            Pseudo Genes (multiple problems)  :: 8 of 33
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..21750
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN40601845-rid21577343.denovo.068"
                     /isolate="ST8-SSI-h139-18"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Denmark"
                     /collection_date="2018"
                     /collected_by="Statens Serum Institute"
     gene            174..1625
                     /locus_tag="ACGI5H_002764"
     CDS             174..1625
                     /locus_tag="ACGI5H_002764"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454468.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0005283 - amino acid:sodium symporter
                     activity [Evidence IEA];
                     GO_function: GO:0015293 - symporter activity [Evidence
                     IEA];
                     GO_process: GO:0006814 - sodium ion transport [Evidence
                     IEA];
                     GO_process: GO:0006865 - amino acid transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="alanine/glycine:cation symporter family protein"
                     /protein_id="HFG9698461.1"
                     /translation="MDFFNGILTSINNAVVYVNNYLWSYILIIMLVVIGIYFTIKTNF
                     VQFRYFIEMFRLLGDGTANKNAKKEGKISSFQAFCISTSSRVGTGNIAGIAIAVVAGG
                     PGAVFWMWLIALIGSASSFVESTLAQIYKVKDGQAFRGGPAYYMEQGLNKKWMGILFS
                     ILITICYGFVFNAVQANTVSLAFNNAFGISKMAMGIGLGILTAIVIFGGVHRVAKVSE
                     IIVPVFAGLYILVALAIVVMNITEIPSVIALIVESAFDFKGMAIGTFMGVVMTGVKRG
                     LFSNEAGMGSAPNAAATAHVTHPVKQGLIQSLGVFTDTIIICSCTAFMVLLYSGYSSS
                     GATGIELAQEALTHHIGPVGNIFIAVCIFLFAFSSIVGNYYYGESNMEFMSGSKTKLN
                     VFRVFVVGMVLFGSLTQVDVVWNLADLFMALMAIINLIAIALLGKYAFIALKDYTSQK
                     KSGIKDPVFIADEIEGLEKVSEWHRELSEEHLG"
     gene            complement(1844..2305)
                     /gene="ribE"
                     /locus_tag="ACGI5H_002765"
     CDS             complement(1844..2305)
                     /gene="ribE"
                     /locus_tag="ACGI5H_002765"
                     /EC_number="2.5.1.78"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454467.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009349 - riboflavin synthase complex
                     [Evidence IEA];
                     GO_function: GO:0000906 - 6,7-dimethyl-8-ribityllumazine
                     synthase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="6,7-dimethyl-8-ribityllumazine synthase"
                     /protein_id="HFG9698462.1"
                     /translation="MIYEGKLIGKDLKIGIINSRFNEFITSKLLSGAEDCLLRHDVSP
                     ENIEIVWVPGAFEIPLVAQKMAKSGKYDAIICLGCVIRGATSHYDYVCSEVSKGIAKV
                     SLDSELPVIFGIVTTENIEQAIERAGTKAGNKGYDCAMNALEMANLFKSLN"
     gene            complement(2410..3603)
                     /locus_tag="ACGI5H_002766"
     CDS             complement(2410..3603)
                     /locus_tag="ACGI5H_002766"
                     /EC_number="3.5.4.25"
                     /EC_number="4.1.99.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889591.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003935 - GTP cyclohydrolase II activity
                     [Evidence IEA];
                     GO_function: GO:0008686 -
                     3,4-dihydroxy-2-butanone-4-phosphate synthase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional
                     3,4-dihydroxy-2-butanone-4-phosphate synthase/GTP
                     cyclohydrolase II"
                     /protein_id="HFG9698463.1"
                     /translation="MFNTIEEAIEDIKNGKMVIVVDDESRENEGDLLMAAEMATPESI
                     NFMATYGRGLICLPATEKKFKSLNIPLMVRENTDTFQTAFTVTIDGADTLTGISAYER
                     AETVKLFCDENSTSKDFKTPGHIFPLIAKTGGVLVRDGHTEASVDLARLAGFKEIGLI
                     CEIMKDDGTMARVDDLMIFKEKHNLKIITIKDLIEYRKINETTIEKVSSAFLPTKYGN
                     FEIIGYRDTYSNEEHIALTYGNINIENTLVRLHSECLTGDVFHSLKCDCGLQLESSMK
                     KIVENGSGVLIYMKQEGRGIGLLNKIKAYKLQEEGYDTVEANLMLGFEEDMRDFYMAA
                     QILKNLNIKSINLLSNNPDKINQLEKYGIKIENRIPINEEINDFNKLYLKTKKDKMGH
                     LLDII"
     gene            complement(3626..4291)
                     /locus_tag="ACGI5H_002767"
     CDS             complement(3626..4291)
                     /locus_tag="ACGI5H_002767"
                     /EC_number="2.5.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430166.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="riboflavin synthase"
                     /protein_id="HFG9698464.1"
                     /translation="MFTGIVEEVGILRKITANGKSGKVTILSNKILDGTNLGDSIAVN
                     GVCLTVSNLGKNEFTADVMMETIRSTNLGLLNANDKVNLERAMSLSSRFGGHIVTGHV
                     DGKGTICKFEKDENAVLVSIRPDKKLLSSMILKGSVAIDGVSLTISYLDDEIFKVSII
                     PHTKINTILLTKNVGDFVNLESDVIGKYVNNFMANNYKELNSNSNNHKSNIDKDFLFK
                     NGF"
     gene            complement(4325..5437)
                     /gene="ribD"
                     /locus_tag="ACGI5H_002768"
     CDS             complement(4325..5437)
                     /gene="ribD"
                     /locus_tag="ACGI5H_002768"
                     /EC_number="1.1.1.193"
                     /EC_number="3.5.4.26"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896839.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008703 -
                     5-amino-6-(5-phosphoribosylamino)uracil reductase activity
                     [Evidence IEA];
                     GO_function: GO:0008835 -
                     diaminohydroxyphosphoribosylaminopyrimidine deaminase
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional
                     diaminohydroxyphosphoribosylaminopyrimidine
                     deaminase/5-amino-6-(5-phosphoribosylamino)uracil
                     reductase RibD"
                     /protein_id="HFG9698465.1"
                     /translation="MNFVNQKEKDIYYMKKAIELAKNGEGFVNPNPLVGCVIVKASNI
                     IGKGYHEKFGSNHAEVNAINSAKQSLKDSTLYVNLEPCSHYGKTPPCVDKIIQNKIKR
                     VVISTLDPNPLVCGNGVKKLKDNNIDVTVGILEDEARDLNEAFFYHIKNKRPLCIVKS
                     AVSLDGKIATKSLESKWISNESSRYLTHKYRNKYQSIMVGINTVLNDNPLLTCRLNQE
                     KVSHPTRIVIDTHLKLPLNSNLVKDKTSKTIVFTCCKESIKLSMLKENNVETIISPSK
                     NNLVDLEFVMYKLGELNIDSVLVEGGATLNDSLFRNKLVDKVKLFLSPKIIGGKDAPT
                     FVSGEGINHLSDSTQLTINNVTLIDGDILIESDVLN"
     regulatory      complement(5569..5690)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00050"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="FMN riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="flavin mononucleotide"
                     /db_xref="RFAM:RF00050"
     gene            5879..8362
                     /gene="recQ"
                     /locus_tag="ACGI5H_002769"
     CDS             5879..8362
                     /gene="recQ"
                     /locus_tag="ACGI5H_002769"
                     /EC_number="5.6.2.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729557.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003678 - DNA helicase activity [Evidence
                     IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA];
                     GO_process: GO:0009432 - SOS response [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA helicase RecQ"
                     /protein_id="HFG9698466.1"
                     /translation="MNKKLLEILSKYYGYTSFRKGQESIINSILSEKDVLAIMPTGGG
                     KSICYQIPALILDGMTIVISPLISLMKDQVDALKTMGISAAFINSSLSSKEFNEILNN
                     IRKNNYKILYIAPERLDAQEFIELINNNNVSQVAIDEAHCVSQWGHDFRLSYRRISDF
                     IKNLPKRPIVTAFTATASEEVRTDIINLLCLENPDYYITGFDRENLSINIVKSSSKNK
                     YILDYIQNHKNESGIIYVATRKEVENIYNGLSKRNISVSKYHAGLSKNERSKNQEDFI
                     NDNVDIMVATNAFGMGIDKPNIRWVIHYNMPQSIENYYQEIGRAGRDGEKSECVLLFS
                     PGDVHIQKYLIDIGVENPERKLFQHKKLQYMIDLVYSNSCYRKTILSYFGENYIDNCN
                     NCSNCLVEGEIVDKTIDAQKVISCVARMKRSYGVTTIVDVLRGSKNKKILQLGLNTLS
                     TYNIMRDYSSEDLKNFVNTLVSHGFLDLVETLGNGNRGSFPTIRLNEMSMKVLKGEVK
                     VEFKEIVMTKSLEVEDELYNALRELRHSIASEERIAPYMVFGDGTLRAMSSSYPINKE
                     EMLDISGVGEIKYQKYGRDFEAVIKEYVEKNNINKKIDEKNVDSKNVNSDFLEVNTDK
                     VLYEKLLVIREEYATKEKLPAYMILANKALKEISGRYPLDEEQLKDISGIGGVKFEKY
                     GASILAEVNKYVKENNINVIWEKKGKRKLILDGESRKNNEIALDLLNQGKDIQSISQE
                     IEVSLSTIIGYVHDYVKDGHSISFELGLENFYNEDKKKMILEVCEKVGYDNLNNIKRK
                     LPDSIKYENIRAVILDSYLENLKNNIIAE"
     regulatory      8451..8562
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00059"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="TPP riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="thiamine pyrophosphate"
                     /db_xref="RFAM:RF00059"
     gene            8704..10005
                     /gene="thiC"
                     /locus_tag="ACGI5H_002770"
     CDS             8704..10005
                     /gene="thiC"
                     /locus_tag="ACGI5H_002770"
                     /EC_number="4.1.99.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889633.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0051536 - iron-sulfur cluster binding
                     [Evidence IEA];
                     GO_process: GO:0009228 - thiamine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphomethylpyrimidine synthase ThiC"
                     /protein_id="HFG9698467.1"
                     /translation="MNYTTQMDAARKGIITKEMEIVSQKEQVDVNELRELIANGQVVI
                     PANKNHKSLSAEGVGKNLRTKINVNLGISRDCKDIEKELEKVRVAIDMKAEAIMDLSN
                     YGKTREFREKVVEMSPAMIGSVPMYDAVGYLEKELKDITEEEFLNVIRQHAIDGVDFI
                     TIHAGLTRSVCQKIKNHERLTHIVSRGGSLLFAWMELNNKENPIYTNFDKILDICEEY
                     DVTLSLGDACRPGCIKDSTDGVQIQELVVLGELTKRAWERNVQVMIEGPGHMAIDEIE
                     ANVVLEKRLCHGAPFYVLGPLVTDIAPGYDHITSAIGGALACAKGVDFLCYVTPAEHL
                     RLPNLDDMKEGIIAAKIAAHAGDIAKNVKGAREWDNKMSKARADLDWCEMFRLAIDPE
                     KAKRYRDESTPTHEDSCTMCGKMCSMRTVKKILNNEELNLI"
     gene            10059..10253
                     /gene="thiS"
                     /locus_tag="ACGI5H_002771"
     CDS             10059..10253
                     /gene="thiS"
                     /locus_tag="ACGI5H_002771"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430174.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003824 - catalytic activity [Evidence
                     IEA];
                     GO_process: GO:0009228 - thiamine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sulfur carrier protein ThiS"
                     /protein_id="HFG9698468.1"
                     /translation="MKVNGKEIEFEKDLTVIDLLNKYNLKSDRVVVEVNLEIIEESNY
                     NTYVLKDEDIVELISFIGGG"
     gene            10246..11049
                     /gene="thiF"
                     /locus_tag="ACGI5H_002772"
     CDS             10246..11049
                     /gene="thiF"
                     /locus_tag="ACGI5H_002772"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420389.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016779 - nucleotidyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0009228 - thiamine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="thiamine biosynthesis protein ThiF"
                     /protein_id="HFG9698469.1"
                     /translation="MVKIKIFVNELLTDVEENTTAYKVRDSYNNKCDVLVLNGYPIKT
                     DMTLCENDKLTLIQKGVKPSLDELESLLIARHTPNIHNKLKKGKVAILGLGGLGSNIA
                     ISLARIGVGELLLIDYDVVEPSNLNRQQYFIDDIGKLKTDAMIENIKKINPFIKLNKR
                     DIFLNKNNMDTIKDSDLIIEAFDDASCKAQVCNYVLINLKDKYLIASSGMAGYYDSNI
                     ITTKKIKDRFYICGDFVNEAKFGEGLMAPRVAICANHMANLATQILIDM"
     gene            11112..11882
                     /locus_tag="ACGI5H_002773"
     CDS             11112..11882
                     /locus_tag="ACGI5H_002773"
                     /EC_number="2.8.1.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018592874.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:1990107 - thiazole synthase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="thiazole synthase"
                     /protein_id="HFG9698470.1"
                     /translation="MDKLVLGGHEFNSRLLVGTGKYGSNNILPEVIKESGSEIITMAL
                     RRVDLDNKQENILTYIPKEMTILPNTSGATNAEEAVRIARISRKMGCGDFIKIEVISD
                     TRYLLPDNEETIKATKILADEGFIVLPYMTPDLYAGRRLIEANAAAVMPLGAPIGSNR
                     GLQMKEMIRIMIDELDIPIIVDAGIGKPSQAMEAMEMGADAVLVNTAIASAGDPVQMA
                     RAFKLAVEGGREAYIAKTGNVSEFANASSPLTGFLGNL"
     gene            11899..13002
                     /gene="thiH"
                     /locus_tag="ACGI5H_002774"
     CDS             11899..13002
                     /gene="thiH"
                     /locus_tag="ACGI5H_002774"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454452.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005506 - iron ion binding [Evidence IEA];
                     GO_function: GO:0016829 - lyase activity [Evidence IEA];
                     GO_function: GO:0051539 - 4 iron, 4 sulfur cluster binding
                     [Evidence IEA];
                     GO_function: GO:1904047 - S-adenosyl-L-methionine binding
                     [Evidence IEA];
                     GO_process: GO:0009228 - thiamine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="2-iminoacetate synthase ThiH"
                     /protein_id="HFG9698471.1"
                     /translation="MSFYDVIEKYRDFDFDGYLNNVTDNDVLRSLSKDKLEDFDILNL
                     LSKTAVKHLEDMAQKAHKLSVQYFGKTVCLYTPMYIANYCVNQCVYCSYNIKSGIKRK
                     KLTMDEIREEGEVISKEGFKHLLVLTGESSFHSSVEYIGEAIEILREKFPSIGIEVYP
                     MEVEEYKYIVDKGVEGLTVYQETYDEEIYKRVHIKGPKSNYKFRLDAPERGAKAGMRT
                     LSIGALLGLNDFRKETFFTILHGKYLKTKYPHIELSYSTPRMRPFKGCFEELVDISDT
                     DLVQAMVCMRLFDPHAAINISTRENLEMRSHIIPLGVTKLSAGVSTDVGGHSQDEHDT
                     AQFKINDESTVKDVEKMLNSIGYQHVFKDWERF"
     gene            13003..13692
                     /locus_tag="ACGI5H_002775"
     CDS             13003..13692
                     /locus_tag="ACGI5H_002775"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889638.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiamine phosphate synthase"
                     /protein_id="HFG9698472.1"
                     /translation="MYLITNRKLCSEERYLEVIKESILSGVENIIIREKDLEYQELRK
                     LYMKIKTKINCIDFQEQISDESLKTNINQKEFRNKFKVNFIINSNIEFFEKVDCQGIH
                     LPFKLFLNLIENKYNFNENKILGLSLHKVEEVDYLEKLIRNQNIKIDYITLSHIYETK
                     CKEGLNPKGIELLKEAKKITDIKIIALGGILPSNVKETLKYCDDFAIMSTIMRSKDIK
                     KTISNYNEKLN"
     gene            13880..15274
                     /locus_tag="ACGI5H_002776"
     CDS             13880..15274
                     /locus_tag="ACGI5H_002776"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422454.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YfcC family protein"
                     /protein_id="HFG9698473.1"
                     /translation="MTDSKKKRFIIPHTFTIIFLLIVLMAILTWIVPSGEFSREDVEG
                     RMVVVPGTYQSVESNPQGFADVFKAPIEGFIDSAEVVGFVLIVGGAFGIVNRTGAIEA
                     GIASVISKFKGKELLIIPISMILFGLGGTTFGMAEETLPFYMIFVPLMTSLGYDSLTA
                     IAIVFIGAAAGAAASTINPFSVGIAQALAQLAPGSGVTYRVVIFIAYILISIAFVMYY
                     AKKVKENPESSIVYEIDKNNKSILNQTSTEIKEFTFKEVSVLAIFGIGMAIMIWGVLS
                     QGWYIPEISMCFAAIGVLSGLVGRLSQIEISESFIDGAKDLASAALAIALARGIVIIA
                     QNGFIIDTILNSAAAFLGGLPKVIFVYLSFFLEAALAFLIPSSSGLASLTVPVLAPLG
                     DLVNISAQVIVTAYQFGVGLTNFITPTSGVLMGALAVAHIPFSKWVRFIMPILLILTA
                     VSLVFLTIGIYIGF"
     gene            15791..17158
                     /locus_tag="ACGI5H_002777"
     CDS             15791..17158
                     /locus_tag="ACGI5H_002777"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430181.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0015969 - guanosine tetraphosphate
                     metabolic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GTP pyrophosphokinase family protein"
                     /protein_id="HFG9698474.1"
                     /translation="MGLKEFDFIEESIDMLRTMSPTLETISDEIEEYFENILDEKNQE
                     YINVTSRIKSESSLREKIIRNRYLKKYGEASNLIHNVSDLIGLRIECRFIEDENKIYR
                     LLRRYFNKTDDKINYYNKENKNIKLKLSERQPNKQKNGFEIYKIDGVFAYLDREVKFE
                     LQIKSLVNVFWSEIEHKIIYKNNTYLLADKFIKDMMDSIKNNLTMIDNQLLSIYKNFH
                     SGKSFNMKVSKKEIEKLFAKLVYDAFSEKMNKSIGFVVDFKKPCETILNYSFNKQDIS
                     DEVLGNFMLDEFARLNEIVNKDIDFNEQIEFEREPTFDDKFCKDLGNHFRSRLNTEFP
                     WNLFFRILFEIEPYNNTKDFENFVEFIKENVLLEENREQLLCQFEEDSKLIIEDIYDC
                     IFNSISEIDSVEILYNYNLEKINFTSSEIINCICREYECYGEYLEEKEKLMNTFKEKI
                     IQIFE"
     gene            17183..17791
                     /locus_tag="ACGI5H_002778"
     CDS             17183..17791
                     /locus_tag="ACGI5H_002778"
                     /EC_number="2.7.7.77"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729555.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_function: GO:0061603 - molybdenum cofactor
                     guanylyltransferase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="molybdenum cofactor guanylyltransferase"
                     /protein_id="HFG9698475.1"
                     /translation="MRHFSNIYELSKIILEEAICIEKTGVILAGGKNSRMGRDKAFLE
                     LHDKLFIEIAIEAFKNFDELIIISNNEELYSKYDIKVYNDIVKDVGPIGGIYTALEYA
                     KYDIVTIACDMPYLNNQIVERIANKMDDKSVISVTNGKLQPLCSGYKKSIINKVSLCI
                     RENDLKLRSFIDKIDKSYIYFDEEDLFLNVNTVDEYKKLTKV"
     gene            17839..18210
                     /locus_tag="ACGI5H_002779"
     CDS             17839..18210
                     /locus_tag="ACGI5H_002779"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454444.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0120225 - coenzyme A binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="CoA-binding protein"
                     /protein_id="HFG9698476.1"
                     /translation="MNLLKCDSWAVILNNSDKESKAYKILDELKRNMYKVVAIDEEKK
                     PIEGIDVYECLKDVPHNIDVVAIIDKQSKMDVILEEVELLDIQNMWFEKGSFSEMMIK
                     KTKDLKLNIEYNLSLYDELTR"
     gene            18389..18727
                     /locus_tag="ACGI5H_002780"
     CDS             18389..18727
                     /locus_tag="ACGI5H_002780"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420397.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heavy metal-binding domain-containing protein"
                     /protein_id="HFG9698477.1"
                     /translation="MLIVTTEKVEGKKISKVLGLVRGSTIRAKHVGKDIGASFKNLVG
                     GELTGYNEMLTEARQIAIGRMVEDAEAKGANAVIAFRLSSASVMQGAAEMLAYGTAVV
                     LEDDNSILEK"
     gene            19193..19696
                     /locus_tag="ACGI5H_002781"
     CDS             19193..19696
                     /locus_tag="ACGI5H_002781"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893248.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MogA/MoaB family molybdenum cofactor
                     biosynthesis protein"
                     /protein_id="HFG9698478.1"
                     /translation="MFNVAIITLSDKGYEGKREDITGKKLTEFVENTGVYKVTEYVLI
                     KDDKEMLKENIIRLCNSNKIDLILTNGGTGFSKRDITPEATKEVLEKEIPGLSEYMRM
                     KSTEITKKAILSRGVSGIRNNSIIINLPGSPKGAVENLSFIIDVLDHGIEVLRGEATE
                     CATKKSE"
     gene            19743..20702
                     /gene="moaA"
                     /locus_tag="ACGI5H_002782"
     CDS             19743..20702
                     /gene="moaA"
                     /locus_tag="ACGI5H_002782"
                     /EC_number="4.1.99.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889647.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_function: GO:0051539 - 4 iron, 4 sulfur cluster binding
                     [Evidence IEA];
                     GO_process: GO:0006777 - Mo-molybdopterin cofactor
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GTP 3',8-cyclase MoaA"
                     /protein_id="HFG9698479.1"
                     /translation="MIDKYGRKIDYLRISLTDKCNLRCVYCMPPDVKFDKNYINENLS
                     FEDYKFIIKAMAEQGITKIRFTGGEPLLYPKLNELIKFTKEECGINNIGMTTNAIGLS
                     DRIFELEKCGLNKVNISLDSLKEYKYKSITRGGNLKDVLKSIESCLNLGIKVKLNCVA
                     ISGFNDDELKDFMFLTVKSPIDVRFIELMPLGEANRVYKKGYFNVKEMIEKIYGLYKV
                     KNDEKSTAEYYMFKGAKGRIGIITPLSCSFCNTCNRIRLTSSGAIKLCLHSKEEIDIK
                     PFLHKPLLFRESMKDIIKQKPEKHHLIENKCSDTNRRMYEIGG"
     gene            20706..21176
                     /gene="moaC"
                     /locus_tag="ACGI5H_002783"
     CDS             20706..21176
                     /gene="moaC"
                     /locus_tag="ACGI5H_002783"
                     /EC_number="4.6.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420402.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0061799 - cyclic pyranopterin
                     monophosphate synthase activity [Evidence IEA];
                     GO_process: GO:0006777 - Mo-molybdopterin cofactor
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cyclic pyranopterin monophosphate synthase MoaC"
                     /protein_id="HFG9698480.1"
                     /translation="MLTHINEKGYAKMVDISEKDDTKRTAVATATITLSKEALEKVKN
                     GQIKKGDVLSVAQVAGIMGAKNTSSNIPMCHQIKLVGCDLEFDVDDSMSAIKIYATCK
                     SLGKTGVEMEALNACSLAALTIYDMCKAVDKKMVISNIHLVEKTGGKSGDFKFE"
     gene            21212..21643
                     /locus_tag="ACGI5H_002784"
     CDS             21212..21643
                     /locus_tag="ACGI5H_002784"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430188.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003824 - catalytic activity [Evidence
                     IEA];
                     GO_function: GO:0030151 - molybdenum ion binding [Evidence
                     IEA];
                     GO_function: GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MOSC domain-containing protein"
                     /protein_id="HFG9698481.1"
                     /translation="MAKVVSINISEKKGVIKVPVQCAELKINHGIVGDAHAGNWHRQI
                     SLLGKESIDKMKMKGFDQLKYGDFAENVTTEGIEVFSLPVGTKLRIGQCEVEVTQIGK
                     KCHNGCEIKKLTGDCVMPREGIFVKVLKEGIINVNDSIDVI"
BASE COUNT         8389 a         2343 c         3754 g         7264 t
ORIGIN      
        1 ttgatttgaa tataaaactg caatatatta aaaaaattat tcattttaaa ccttgtaatt
       61 tgattttata aatattataa ttaaattaat gaatttttaa caaggaatta ttcatttttt
      121 tgattttaag atttattgag aaaacaaaac taaatagggg ggtaattaat ataatggatt
      181 ttttcaatgg tattttaacg agtattaaca atgcagtagt atatgtaaac aattacttat
      241 ggtcgtatat cttaattata atgttagttg taattggtat ttactttact attaaaacaa
      301 attttgtaca attcagatat tttatagaaa tgtttagact tctgggtgat ggtacagcga
      361 ataaaaatgc aaaaaaggaa ggaaaaatct cttcatttca agcattttgt ataagtacat
      421 cttcaagagt tggaactgga aatatagctg gaatagcaat tgcagtggta gcaggaggac
      481 ctggtgctgt attttggatg tggcttatag cattaattgg ttctgcatca agctttgttg
      541 agagtacatt agctcagatt tacaaagtga aagatggtca agcttttaga ggtggaccag
      601 cgtattatat ggaacaaggt ctaaataaaa aatggatggg tattttattc tcaatactta
      661 taactatatg ttatggtttt gtatttaatg cagttcaagc aaatactgtt tcacttgcat
      721 ttaataatgc atttggaata agtaaaatgg ctatgggaat aggtcttgga attttaactg
      781 caatagttat ttttggtgga gtgcatagag ttgcaaaagt ttctgaaata atagttcctg
      841 tatttgcagg attatatata ttagttgctt tggctatagt tgtaatgaat ataacagaga
      901 taccaagtgt tatagcattg atagttgaaa gtgcatttga ttttaaagga atggcgattg
      961 gtacatttat gggagttgta atgactggag tgaagagagg tctattttct aatgaagcag
     1021 gtatgggtag tgctcctaat gctgctgcaa cagcacatgt aactcatcct gtaaaacaag
     1081 gtttaattca atctttaggt gtttttacag atactataat aatatgtagt tgtacagcat
     1141 tcatggtatt attatattca ggttatagta gtagtggagc aactggaatt gaattagctc
     1201 aagaagcttt aactcatcat ataggaccag ttggaaatat atttatagca gtttgtatat
     1261 tcttgtttgc atttagttct atagttggta attactatta tggtgaatca aatatggagt
     1321 ttatgagtgg aagtaagact aaacttaatg tatttagagt ttttgttgta ggtatggttt
     1381 tatttggttc acttactcaa gtggatgtag tttggaatct tgcagactta tttatggcat
     1441 tgatggcgat aataaactta atagcaatag cacttttagg aaaatatgca tttattgctt
     1501 taaaagatta tacaagtcaa aaaaaatcag gaataaaaga ccctgtgttt attgcagatg
     1561 aaatagaagg cctagaaaag gtatcagagt ggcataggga attatctgag gaacatttag
     1621 gataaaaaat agtataaaat tataaaacca ttttgaaaga ctagagtatg tatatacttt
     1681 atatgaatat aatattgaat taatttatat tactggaatt tttaattcca gtaatatttt
     1741 tttattatat aatttagctt tattaaaagt ttttattatt aaaaatagct tatttatcgt
     1801 aaagtgaatg atattgggtt ttaattatta tgaatgttag tatttaattt aaagacttaa
     1861 ataaatttgc catttctagc gcattcatag cacaatcata acctttattt ccagcttttg
     1921 tacctgctct ttcaatagct tgttcaatat tttctgtagt tacgattcca aatataacag
     1981 gtaattcact gtctaaagat actttggcta tccctttaga gacttcacta catacataat
     2041 cataatgaga agtagcccct cttataacac agcctaaaca gattatagca tcatacttac
     2101 cacttttagc cattttttga gcaacaagag gaatctcaaa agctccaggt acccaaacta
     2161 tttctatatt ttctggagaa acgtcatgtc ttaaaagaca gtcttcagct cctgataaaa
     2221 gttttgatgt tataaattca ttaaaacgag aatttattat acctattttt aaatcttttc
     2281 caataagttt tccttcatat atcattttta cttcctccaa ttttatttat gttatagatt
     2341 tatatttata aatatcttta atttaattat aaaaaactac ttagtagaaa aatatcatca
     2401 tataatcatt tatataatat ctaaaagatg tcccatttta tcttttttag tttttaaata
     2461 tagcttatta aagtcattaa tttcttcatt aatagggatt ctattttcga tttttattcc
     2521 atatttctct aattgattta ttttatctgg gttattactt aaaagattta tactttttat
     2581 gtttaaattt tttaatattt gagcagccat atagaaatct ctcatatctt cttcaaatcc
     2641 aagcattaaa tttgcttcaa cagtatcgta accttcttct tgaagtttat aagccttaat
     2701 tttatttaaa agaccaatac ctctaccttc ttgcttcata taaattaaaa ctccacttcc
     2761 attttccaca attttcttca tagaagattc tagctgtaat ccacaatcac attttagaga
     2821 gtggaacaca tctcctgtta aacattcaga atgaagtcta actagagtat tttctatatt
     2881 tatatttcca taagtaaggg caatgtgttc ttcatttgaa taagtatctc tatatcctat
     2941 gatttcaaaa tttccatatt ttgtcggaag gaaagcacta gatacttttt ctatagtagt
     3001 ttcatttatt ttgcggtatt ctataaggtc ttttatagtg atgattttta aattatgctt
     3061 ttctttgaaa atcattaaat catcaactct tgccattgta ccatcatctt tcattatttc
     3121 acagataaga ccaatctctt taaaacctgc aagtctagca aggtctactg aggcttctgt
     3181 atgtccatcc ctgacaagaa ccccaccagt ttttgctatt aaaggaaaga tgtgaccagg
     3241 cgttttgaaa tctttacttg tagaattttc atcacagaat aattttacag tttcagctct
     3301 ttcatatgca gatataccag ttagagtatc tgctccatct atagtaacag taaaggctgt
     3361 ttgaaatgta tctgtatttt ctctaaccat aagaggtata ttaagacttt taaatttttt
     3421 ttcagtggca ggtagacaaa ttagacctct accatatgta gccataaaat ttattgattc
     3481 aggagtagcc atttcagctg ccatcaataa atctccttca ttctctctac tttcatcatc
     3541 aaccacgatt accattttcc cattttttat atcttcaata gcttcttcaa tagtattaaa
     3601 catgtaattc actcctttat tatttttaaa aaccattttt aaataaaaaa tctttatcta
     3661 tatttgattt atggttatta ctattagaat ttaattcctt gtagttatta gccataaaat
     3721 tattaacata ctttccaatt acatcgcttt ctaaattaac gaaatctcca acattctttg
     3781 tcaagagaat agtgttaatt ttagtatgag gtataataga aaccttaaat atttcatcat
     3841 ctaaatatga tatagttaaa cttacaccat caatagcaac agaacctttg agtatcattg
     3901 aggataaaag ttttttatca ggtcgtatac ttactaaaac tgcattttca tctttttcaa
     3961 atttgcagat agttccttta ccatcaacat gacctgttac tatatgacca ccaaatcttg
     4021 aagaaagact catagctctt tcaagattta ccttgtcatt tgcatttaat aaacctaaat
     4081 ttgtggaacg aattgtctcc atcataacat cggctgtaaa ttcatttttt ccgaggtttg
     4141 aaacagttag acaaactcca tttacggcta tactatctcc aagatttgtg ccatctaata
     4201 ttttatttga tagtatggtt acttttccac tcttaccatt agcagtaatt tttctaagta
     4261 ttccaacttc ttctactatg ccagtaaaca tcctaacctc ctatatgaat gtattaacaa
     4321 aaatttaatt taaaacatct gattctataa gaatatcgcc atctatcaaa gttacattat
     4381 tgattgttaa ctgtgttgaa tctgacaaat gatttattcc ttctccagaa acgaatgtag
     4441 gtgcatcttt accacctata atcttgggtg atagaaataa tttgacctta tcaactaact
     4501 tatttctaaa gagactgtca ttgagagtag caccaccttc aactagaaca gaatcaatgt
     4561 ttaactctcc taatttatac attacaaact ccaaatctac taagttgttt tttgaaggag
     4621 aaattattgt ttcaacatta ttttctttta acatagataa ttttatactt tctttgcaac
     4681 atgtgaaaac tatagtttta ctggttttat ctttaaccaa attactatta agtggcaact
     4741 ttaggtgtgt atctattact attcttgtag gatgagacac tttttcttga ttgagcctac
     4801 aagttagtaa aggattatcg ttcaaaactg tatttatgcc aaccattata ctttggtatt
     4861 tatttctgta tttatgagtt agataccttg atgattcatt agatatccat tttgattcta
     4921 gtgattttgt agcaatttta ccatctagac ttactgctga ttttacaata caaagaggtc
     4981 ttttgttttt tatatgataa aaaaatgcct catttaaatc tcttgcttca tcttctaata
     5041 ttcccacagt aacatcaata ttgttatctt ttaatttttt tactccatta ccacaaacaa
     5101 gtggatttgg gtctaatgta gatattacaa ctctcttaat cttattttgt ataattttat
     5161 ctacacaagg aggcgttttc ccataatgag aacatggttc taagtttaca taaagagtag
     5221 agtcttttag actttgttta gcactgttta tagcatttac ttcagcatga ttagagccaa
     5281 atttctcatg atatcctttg cctattatat tactagcttt aacaattaca cacccaacta
     5341 atggatttgg atttacaaag ccttctccat ttttagccaa ttcaatagct tttttcatat
     5401 aataaatatc tttttctttt tgattcacaa aattcacaat atgtacacct cctgtttaat
     5461 tggataattt ttaaacaaaa aaccctgaga attaactcag ggtttagaat aatctacaat
     5521 aaatgtttaa taaatgtaga acaaaattgc tctacaaaaa cactcattaa atatcttctt
     5581 ccatccagac tttactgtcg gctttggaat ttaaccaaat caaccaagtt ttaccttggc
     5641 tcgcgggcta taccgccgat tgggaatttc accctacccc gaagattaag tattaaattt
     5701 atatttagaa tgtatcataa attattttac tttgcaaact atttttttaa aaaatatatg
     5761 ttaatatata atatagaatg tctataaact ttgaaatacc acgattgtga atataaaaat
     5821 aaaaatttga acataatcag gaaagaagtc taattaattt aaattaggag agtaatatat
     5881 gaataaaaaa cttttagaaa tactatcaaa atactatgga tatacaagtt ttagaaaagg
     5941 tcaagaatct ataataaact ctatcttaag cgaaaaagat gtgttagcta ttatgccaac
     6001 aggaggggga aaatcaatat gttatcaaat tccagctttg attttagatg gaatgacaat
     6061 agtaatttct ccacttatat cacttatgaa agaccaagta gatgccttaa agactatggg
     6121 aattagtgct gcttttataa atagttcatt aagtagcaaa gaatttaatg aaatattaaa
     6181 taatattaga aaaaataatt ataaaatact ctatattgct ccagagagat tagatgcaca
     6241 agagtttatt gagctaataa ataataacaa tgtaagtcaa gttgcgatag atgaagcaca
     6301 ttgtgtatct caatgggggc atgattttag gttgagttat agaaggattt ctgattttat
     6361 aaaaaatttg cctaaaagac ctatagttac agcatttact gcaacagctt cagaagaggt
     6421 aagaactgat ataataaatt tactgtgttt agaaaatcca gattattata taactggatt
     6481 tgatagagag aatttatcaa taaatatagt aaaatcatct agtaaaaata agtatatttt
     6541 agattatatt caaaatcata aaaatgagtc tggaattata tatgttgcaa ctagaaagga
     6601 agttgaaaat atatataatg gtttatctaa gagaaatata tctgtgtcaa aatatcatgc
     6661 aggtttatct aaaaatgaaa gaagtaaaaa tcaagaagat tttataaatg ataatgtgga
     6721 tataatggta gcaacaaatg catttggaat gggtattgat aaacctaata taagatgggt
     6781 tatacattac aatatgcctc aaagtataga aaactactat caagaaatag gtagagctgg
     6841 tagggatgga gaaaaaagtg agtgtgtact tttattttct ccaggagatg tacatataca
     6901 aaaatattta attgatattg gagttgaaaa tcctgaaaga aaattatttc agcataagaa
     6961 gcttcaatac atgattgact tagtttacag taattcatgc tatagaaaga caatattgag
     7021 ttattttgga gaaaattata tagacaattg caataattgt agcaattgtt tagtagaggg
     7081 tgaaatagta gataaaacta tagatgcaca aaaagtcatt tcatgtgtag ctagaatgaa
     7141 aagaagttat ggtgttacta ctattgtaga tgtgcttaga ggttctaaga ataaaaagat
     7201 tttacagctt ggattaaata ctttgtctac atataacatt atgagagatt attctagtga
     7261 agacttaaag aattttgtaa atacattggt ttctcatggt tttttagatt tagttgagac
     7321 tctaggcaat ggaaatagag gtagttttcc tactataaga ttaaatgaga tgtctatgaa
     7381 agttttaaaa ggtgaagtga aagtagagtt taaagaaatt gttatgacaa aatcattgga
     7441 agtagaggat gagttatata atgctttaag agaacttaga cattcaattg caagtgaaga
     7501 aaggatagct ccatatatgg tatttggaga tggtacactt agagccatgt ctagtagtta
     7561 tccaattaat aaagaagaaa tgctagatat ctctggagta ggagaaatta aatatcaaaa
     7621 atatggtaga gattttgaag cagtaattaa agaatatgtc gaaaaaaata atataaataa
     7681 aaaaatagat gaaaaaaatg tcgattcaaa gaacgttaat agtgatttct tagaggttaa
     7741 tacagataaa gttttatatg aaaaactgtt agtcattaga gaagaatatg caacaaagga
     7801 aaaattacct gcatatatga ttttagccaa taaggctttg aaagaaataa gtggaagata
     7861 tccacttgat gaagaacaat taaaagatat ttctggcata ggtggagtaa aatttgaaaa
     7921 atatggagct agtattttgg cagaggttaa taaatatgta aaagaaaata atattaatgt
     7981 tatttgggag aaaaagggca aaaggaagtt aatattagat ggagaaagta gaaaaaataa
     8041 tgaaatagca ttagatttgc taaatcaagg aaaagatata caaagtatca gtcaagaaat
     8101 agaagtttca ctgtcaacca ttattggata tgtgcatgac tatgtaaagg atggacatag
     8161 tatatcattt gaattaggac tagaaaattt ttataatgaa gataaaaaga agatgatttt
     8221 agaagtttgc gaaaaagttg gctatgataa tttaaataac ataaaaagaa aacttccaga
     8281 ttcaataaag tatgaaaata taagagctgt gatacttgac tcttatcttg aaaacttaaa
     8341 aaataatatt atagcagagt aatttttaac ttaataaaaa ataaaatttg tattattgtg
     8401 ttgaactaat aattttgctg tgttatactg aatttgtaaa aataatgaaa aattagagct
     8461 aggggcgcta gaattggcta gctgagagat aaagccgtaa cttacaaacc ctaataacct
     8521 gatcaagata atgcttgcga agggaagctt tttaatataa ttttattata taaataggca
     8581 aattattcaa tgttaggaga aatttgtcta agtgtatata cgattataag agtgctttcc
     8641 aaacgaggaa aagcactttt tttattttca aaaactataa ctttaatctt ggaggattgt
     8701 aatatgaact atacaacaca aatggatgct gctagaaaag gcataataac taaagaaatg
     8761 gaaatcgttt ctcaaaaaga acaggtagat gtaaatgaat taagagaatt aatagcaaat
     8821 ggacaagttg ttataccagc taataaaaat cataaatctt taagtgcaga aggtgtaggt
     8881 aaaaatttaa gaacaaaaat aaatgtaaat ctaggaattt caagagattg taaggatata
     8941 gaaaaagaac ttgaaaaagt tagagtagca atagacatga aagctgaagc tataatggat
     9001 ttaagtaatt atggcaaaac tagagaattt agagaaaagg ttgttgaaat gtcacctgca
     9061 atgataggtt cagtacctat gtatgatgca gtaggatatt tggaaaaaga attaaaagat
     9121 ataacagaag aagagttttt aaatgtaata agacaacatg ctattgatgg agtagacttt
     9181 attactatac atgcaggtct tacaagaagt gtttgccaaa aaataaaaaa tcatgagaga
     9241 ttgactcata tagtatctcg tggaggttct ttattgtttg catggatgga attaaataat
     9301 aaggaaaatc ctatttatac taattttgat aaaatattgg atatatgtga agaatatgat
     9361 gttacattga gtttaggaga tgcttgtaga ccaggttgta taaaagattc tactgatggt
     9421 gttcaaattc aagaacttgt agtattaggt gaacttacta aaagagcatg ggaaagaaat
     9481 gtacaagtaa tgatagaagg tcctggacac atggctattg atgaaataga agcaaatgta
     9541 gtattagaaa agagattatg ccatggagca cctttttatg ttcttggacc attggttaca
     9601 gatatagcac caggttatga ccatataaca agtgcaatag gaggagcttt agcatgtgcc
     9661 aaaggagtag attttttatg ttatgtaact ccagcagaac atttaagatt gcctaattta
     9721 gatgatatga aagagggtat aatagctgca aagatagctg ctcatgcagg agatatagct
     9781 aaaaatgtta aaggtgctcg tgaatgggat aataagatga gtaaagctag agctgattta
     9841 gactggtgtg agatgtttag acttgcaata gaccctgaaa aagctaagag atacagagat
     9901 gaatcaactc ctactcatga ggatagttgt actatgtgtg gaaaaatgtg ctcaatgaga
     9961 acagttaaga aaatattaaa caatgaggaa cttaatctaa tataattttt ggctagtatg
    10021 actggaataa aaataagctg aaaagaggag gtgatttagt gaaggttaat gggaaggaaa
    10081 ttgaatttga aaaagatttg actgttatag atttattaaa taaatataat ttaaaaagtg
    10141 atagagttgt agttgaagtg aatttagaga taattgaaga atctaactac aatacatatg
    10201 tattaaaaga cgaggacatt gtagagctta ttagctttat tggaggtggt taaaataaaa
    10261 atatttgtaa atgaattatt aacagatgtt gaggaaaata caactgctta taaagttaga
    10321 gatagctata acaataaatg tgatgtattg gtgttaaatg gatatccaat taaaacagat
    10381 atgacccttt gtgaaaatga taaattaaca cttatacaaa aaggagttaa gccatcactt
    10441 gatgaattgg aaagcttgtt gattgctaga catactccaa atatacataa taaattaaaa
    10501 aaagggaaag ttgctatatt gggattgggg ggacttggtt ccaatatagc tatctcttta
    10561 gctagaatag gagtgggaga acttttactt atagattatg atgttgtaga accatctaat
    10621 ttaaatagac agcagtattt tatagatgat ataggaaaac taaaaactga tgccatgata
    10681 gaaaatataa aaaaaataaa tccatttata aaattaaata aacgagatat ttttttaaac
    10741 aagaacaata tggatactat taaggattca gatttaataa ttgaggcctt tgatgatgct
    10801 tcatgtaaag cacaggtatg taattatgta ttaataaatt taaaagataa atatttaata
    10861 gcatcatctg gtatggcagg ttactatgat tcaaatataa taactactaa gaagataaaa
    10921 gacaggtttt atatatgtgg ggattttgtg aatgaagcta aatttggtga agggcttatg
    10981 gctccaaggg ttgccatctg cgcaaatcat atggcaaatt tggcaacgca aatacttata
    11041 gatatgtaaa tattaaaatt agatataaaa aagattgaat attaaaaaaa tttaacgtgg
    11101 agggaaataa tatggataaa ttggtacttg gtggacatga atttaatagc agattattgg
    11161 ttggaacagg taaatatggt tcaaataata tattgcctga ggtaataaaa gaaagtggaa
    11221 gtgaaataat aacaatggca cttagaagag tggatttaga caataaacaa gaaaacatat
    11281 taacgtatat tccaaaagag atgacaatac ttccaaatac atcaggagct actaatgcag
    11341 aagaagctgt aagaatagct agaatatcta gaaaaatggg atgtggagat tttataaaaa
    11401 tagaagtaat atcagatact agatatttac ttcctgataa tgaagaaact ataaaagcta
    11461 caaagatact tgctgatgag gggtttatag ttcttccata tatgacacca gacctttatg
    11521 ctggaagaag acttatagaa gctaatgcag cggcagttat gccacttgga gctccaattg
    11581 gttcaaatag aggtcttcaa atgaaagaaa tgataagaat aatgatagat gagttggata
    11641 taccaataat agtagatgca ggtattggaa aaccatctca agctatggag gctatggaaa
    11701 tgggagctga tgcagtactt gtcaacactg ctatagcttc agcaggagac cctgtacaaa
    11761 tggctagagc atttaaatta gctgtagaag gtggaagaga agcatatatt gcaaaaacag
    11821 gaaatgtgtc agaatttgca aatgcatctt ctcctttaac aggtttttta ggcaatttat
    11881 agaaagtggt gattggtgat gagtttttat gatgtaatag aaaaatatag ggattttgat
    11941 tttgatggat atttaaataa tgttactgat aatgatgttt taagaagttt atcaaaagat
    12001 aagcttgaag attttgatat attaaatttg ctttctaaaa ctgcagtaaa acatttagaa
    12061 gatatggcac aaaaagcaca taaattaagt gttcaatact ttggtaaaac agtatgttta
    12121 tatacaccaa tgtatatagc aaattattgt gttaatcaat gtgtttattg tagctataat
    12181 ataaagagtg gaataaaaag aaaaaaatta actatggatg aaattagaga agagggagaa
    12241 gtaatttcaa aagaaggttt caaacatcta cttgttttga ctggagaaag tagttttcac
    12301 tcaagtgtag aatatatagg tgaggctata gaaatattaa gagagaaatt tccctctata
    12361 ggtatagaag tttatccaat ggaagtagaa gaatataagt acattgtaga taaaggtgtt
    12421 gaaggattaa cagtatatca agaaacttat gacgaggaaa tatataagag agtacatata
    12481 aaaggcccaa aatcaaatta taaatttaga ctagatgctc ctgaaagagg ggcaaaagca
    12541 ggtatgagga ctttatcaat aggtgcactt ttagggctaa atgattttag aaaagaaact
    12601 ttttttacaa tattgcatgg gaaatactta aaaacgaaat atcctcatat tgagctttca
    12661 tattcaacac caagaatgag accttttaaa gggtgttttg aggaattggt agatataagt
    12721 gatactgatt tagttcaagc tatggtatgt atgagattat ttgaccctca tgcagctata
    12781 aatatatcca ctagagaaaa tttagaaatg agaagtcata taataccttt aggagtaact
    12841 aaattgagtg caggtgtatc tactgatgta ggaggtcatt ctcaagatga acatgatact
    12901 gctcaattta agataaatga tgaaagtact gttaaagatg tggagaaaat gctaaactca
    12961 attggttatc agcatgtgtt taaagattgg gaaagatttt aaatgtatct gataacaaac
    13021 agaaaattat gtagtgagga acgatattta gaagttatta aagagtctat attgagtggt
    13081 gtagaaaata taataataag agaaaaggat ttagaatatc aagagctaag aaaattatat
    13141 atgaaaataa aaactaaaat caattgtata gattttcaag agcaaatatc agatgaaagt
    13201 ttgaaaacta atataaatca aaaagagttt agaaataaat tcaaggttaa ttttataata
    13261 aatagtaaca ttgaattttt tgaaaaagtg gattgtcaag gtatccatct tccttttaaa
    13321 ttattcttga atttaattga aaataagtat aattttaatg aaaataaaat actaggatta
    13381 tctttacata aagtagagga agtagattat ttagaaaaat taataagaaa tcaaaatata
    13441 aaaatagatt acataacatt atcacatata tatgaaacta aatgtaaaga aggattaaat
    13501 ccaaaaggaa ttgagctttt aaaagaagct aaaaagatta ctgatattaa aataattgca
    13561 cttgggggaa ttttaccatc taatgtcaag gaaacattaa aatactgtga tgattttgct
    13621 ataatgtcaa ctataatgag gtctaaagat attaaaaaaa ccatatcaaa ttataatgaa
    13681 aagttgaatt agtaaatata gtatattgaa tttttaactt aaataaaaat aaaaaagtta
    13741 tcttttaaat tttaaaaggt agctttttta ttttatatct ttgctaataa aaaattgtaa
    13801 aaagggaaaa ctttagtcag agagattaaa caatatccta gaaagattta aaatttagta
    13861 aagtatggag gacattataa tgactgacag taaaaagaaa cgatttatta taccacacac
    13921 ttttacaata atatttttac taatagtctt gatggcaata ttgacttgga tagtaccaag
    13981 tggtgaattt agtagagaag atgtagaagg tagaatggta gttgtaccag ggacttatca
    14041 aagtgtagaa agtaatcctc aaggatttgc agatgttttt aaagcaccaa tagaaggctt
    14101 tatcgattca gctgaagttg taggttttgt tttaatagtt ggaggtgctt ttggtattgt
    14161 aaataggact ggagctatag aagcaggaat agcttcggtt atctctaagt ttaagggaaa
    14221 agaacttctt ataattccaa tatcaatgat tttatttgga cttggaggta caacatttgg
    14281 gatggcagaa gagacattac cattttatat gatatttgtt ccactcatga catccttggg
    14341 atatgattct ctaacagcaa tagcaattgt atttatagga gcagcagcag gagcagccgc
    14401 ttcaacaata aatccatttt cagttggtat tgcacaggca ctagctcaac ttgctcctgg
    14461 ttcaggagta acttacagag tagttatttt tatagcatat atactaataa gtatagcatt
    14521 tgttatgtac tatgctaaga aggtaaagga aaatcctgaa agttcaatag tatatgaaat
    14581 agataaaaat aataaatcaa tacttaatca aacttcaaca gaaataaaag aatttacttt
    14641 taaagaagta tctgttcttg ctatatttgg aatagggatg gcaataatga tttggggtgt
    14701 tttaagtcaa ggatggtaca ttccagaaat atcaatgtgt tttgctgcaa taggtgtgct
    14761 ttctggattg gttggtagat tatctcaaat tgaaatctca gaaagtttta tagatggagc
    14821 aaaagattta gcatctgcag ctcttgctat agctttggct cgtggaatcg taataattgc
    14881 tcaaaatgga tttataatag atactatatt aaattccgca gcagcctttc taggtgggct
    14941 tccaaaggtt atatttgtat atttatcatt tttcttggaa gctgcattgg catttttaat
    15001 tccatcatct tcaggtcttg cttcacttac agtacctgta cttgctcctc ttggtgattt
    15061 ggttaatata tcggctcaag tgatagtaac cgcttatcaa tttggtgtgg gtcttacaaa
    15121 ctttataact ccaacttcag gagtactgat gggagcactt gcagtagccc atattccatt
    15181 ttcaaaatgg gtaagattta taatgcctat cttgttgatt ttgacagctg tatctctagt
    15241 ctttttaaca ataggtattt atatagggtt ttaattaagt gtagttttat ttaagatatt
    15301 tagtaatggt ataaaatgat aatatgtttt caataaattg ccactaattt aattagtggt
    15361 aatttgtttt ttgtatttaa aaataaatgt atttacttgt attttgaatt aatatctact
    15421 tagacattgt tttaattgtt atatttttat ttaattaagc attgatttat cattttttat
    15481 atttcatata acaatgcaaa aaataatttt tatatagtaa atgacaaaag tttacaataa
    15541 atgtatattt tcttactcat tccttaaaat tactcattta gtttaataac tctcatttca
    15601 tatgtaaagt tggtaaaaaa attaaaatta aaagtaaaaa actaaataaa ttaatgttaa
    15661 tttgaaatat atatgaaggt ttttggagaa tacttactta tgataggaaa aaatgttaaa
    15721 ataatagtgt aatcaaatat aaaggactga aataattaac agttattaaa tattaggagt
    15781 gtaaaaattt atgggattaa aagaatttga ttttattgaa gagtctattg atatgttgag
    15841 gacaatgtca ccaacattag aaactatatc agatgaaata gaagaatatt ttgaaaatat
    15901 cttggatgaa aagaatcaag aatatataaa tgtaacctct agaataaaat cagaatcaag
    15961 tttaagagaa aagataatta gaaatagata tttaaaaaaa tatggagaag caagtaatct
    16021 tattcataat gtttctgact taataggcct aagaattgag tgtagattta ttgaggatga
    16081 aaacaaaata tatagacttt tgagaagata ttttaataaa acagatgaca aaataaacta
    16141 ttataataaa gagaataaga atattaaatt aaaactatct gagaggcaac ccaataagca
    16201 aaaaaatgga tttgaaatat ataaaataga tggagttttt gcgtatttag atagagaagt
    16261 aaaatttgaa cttcaaatta aatctcttgt aaatgtgttt tggagtgaaa tagaacataa
    16321 aataatttat aaaaacaata catatttact tgctgataaa tttataaagg atatgatgga
    16381 ctctataaag aataatctta ctatgataga taatcagctt ttaagtattt ataaaaactt
    16441 tcattcaggg aagtctttta atatgaaagt aagtaaaaaa gaaattgaaa aattatttgc
    16501 gaaactagtc tatgacgctt tttctgaaaa gatgaataaa agtataggtt ttgttgtaga
    16561 ttttaaaaaa ccatgtgaga ctatattgaa ctattctttt aataaacaag atataagtga
    16621 tgaagtttta ggtaatttta tgcttgatga gtttgcaaga ttaaatgaaa ttgtaaacaa
    16681 ggatatagat tttaatgagc aaatagaatt tgaaagagaa ccaacatttg atgataagtt
    16741 ttgtaaagac ctaggaaatc attttagaag tagattaaac acagaatttc catggaacct
    16801 attttttaga atattatttg aaatagagcc atataacaat accaaagact ttgaaaactt
    16861 tgtagagttt ataaaagaaa atgtgctact agaagaaaat agggagcaat tattatgcca
    16921 atttgaagag gatagtaagc ttataattga agatatatat gattgtatat ttaatagtat
    16981 aagtgagatt gatagtgttg aaattttata taactataat cttgaaaaaa taaactttac
    17041 atcaagtgaa atcataaatt gtatatgtag agaatatgag tgttatggtg aatacttaga
    17101 agaaaaagaa aagcttatga atacatttaa agaaaagatt attcaaatct ttgagtaata
    17161 ggtcaatgct gaagtggcgc taatgcgcca tttttcaaat atatatgaat taagtaaaat
    17221 tattttggag gaggcgattt gtatagagaa aacaggtgta attttggcag ggggaaaaaa
    17281 ttctagaatg ggtagagata aagccttttt agagttacat gataagcttt ttattgaaat
    17341 tgcaatagaa gcatttaaaa actttgatga gttgataata atatctaaca atgaagaatt
    17401 atattctaaa tacgatatta aagtttataa tgatatagta aaagatgttg gtccaattgg
    17461 aggaatatat actgctcttg aatatgcaaa gtatgatata gttacaattg catgtgatat
    17521 gccatatcta aataatcaaa tagtcgaaag aatagctaat aaaatggatg ataaaagtgt
    17581 gatttcagtg acaaatggaa agttacaacc attgtgttct ggatataaaa agagtataat
    17641 aaataaagta tctttatgta taagggaaaa tgatttaaag ctcagaagct ttatagataa
    17701 aatagataaa agttatatat actttgatga agaagattta tttttaaatg taaacactgt
    17761 tgatgagtat aaaaaattaa ctaaagttta attagctatg gttgtaaaat agagtaggat
    17821 ttatatggag gagagtttat gaatttactt aaatgcgatt cttgggcagt aatattaaat
    17881 aatagcgata aagaaagtaa agcatataaa atattagatg aacttaaaag gaatatgtac
    17941 aaagttgttg ctatagatga agagaaaaaa cctattgaag gaatagatgt gtatgaatgt
    18001 ttaaaagatg ttccacacaa tattgatgtt gtagctatta ttgataaaca atctaagatg
    18061 gatgtgattt tagaagaagt agagcttttg gatatacaaa atatgtggtt tgaaaaagga
    18121 agctttagtg aaatgatgat taaaaagact aaagatttaa aattaaatat agaatataat
    18181 ttaagtttat atgatgagtt gactagataa aattatattt cttaataata aaaatataat
    18241 tagttaataa aacatattat tttatagtat agattggtta ataaaagtac agattggtta
    18301 atgaaacatt aaattacaat atttgttaaa aaaattgtga gttacatgat ataatgtatt
    18361 aaataggata ctaaggagtt gatatattat gttaatagta actacagaaa aagtagaagg
    18421 taaaaagata tcaaaggttt taggattagt gagaggaagt acaataagag caaaacatgt
    18481 tggaaaagat ataggagcaa gttttaagaa tcttgttgga ggagaactta ctggatataa
    18541 tgaaatgctc actgaagcaa gacaaattgc cataggtaga atggttgaag atgcagaagc
    18601 taaaggtgca aacgcagtaa tagcatttag actgtcttca gcttcagtta tgcaaggagc
    18661 agcagaaatg cttgcttatg gaacagcagt tgttttagaa gatgataata gtattcttga
    18721 aaaataaaat ataaatagtt aaaaagaggc atcttttaaa aattttatgg atgccttttt
    18781 ttatttgaaa aaactaattt gagaagaaat tttaactatt atgacaataa aattagggtg
    18841 atattatata aataagtaaa attatattat ataatgtatg gtatagactt taaaaatttt
    18901 atttgtagag aaaaatatgg acaatgttat aataattata gaaattaaaa gtacttacat
    18961 tcattatgta tgtgacatgt ataattagtt ttatatttaa tacagttttg aagtaatatc
    19021 ttcattttga gaacgttgga ataataaaaa atgtattatt ataggtgata taaataaaaa
    19081 ataaatataa tatgttatat tgctgataga aaagagaata aaagaaaata ggttttatta
    19141 aaagagattt ttatttatag gacttaatca atgtatagag gggtgagaac atatgtttaa
    19201 tgttgcaatt ataacactta gtgataaagg atatgaagga aaaagagaag atataacagg
    19261 aaaaaagtta actgaatttg ttgaaaatac aggagtttat aaagttactg aatatgtact
    19321 tataaaagat gataaggaaa tgctaaagga aaatattata agactttgta atagtaataa
    19381 aatagattta attcttacaa atggaggtac tggtttttca aaaagagata taaccccaga
    19441 agcaactaag gaagtgttgg aaaaagaaat accaggtctg agcgaatata tgagaatgaa
    19501 atccacagaa attactaaaa aggccatact aagtaggggt gtgagtggaa taagaaataa
    19561 ttctataata ataaatttac ctggaagtcc taaaggtgca gttgaaaatc taagttttat
    19621 aattgatgtt ttagaccatg gcatagaagt tttaagagga gaagctacag aatgtgccac
    19681 taaaaaaagt gaatagtata taatctagat agataaaaaa tagacaaaga ggtagataaa
    19741 gtatgattga taagtatgga agaaaaatag actaccttcg tatttcactt acagataagt
    19801 gtaatttaag gtgtgtctat tgtatgccac cagatgtaaa atttgataaa aattatataa
    19861 atgaaaatct aagctttgaa gactacaagt ttattataaa ggctatggct gaacaaggta
    19921 taacaaaaat tagatttact ggaggagaac ctcttttata tcctaaatta aatgagctta
    19981 taaaatttac aaaagaagaa tgtggaataa ataacatagg aatgaccact aatgctattg
    20041 gtctttctga tagaattttt gagcttgaaa aatgtggctt aaataaagtt aatataagtt
    20101 tagattcttt gaaggaatat aagtataaat ccataacaag aggaggaaac ttaaaagatg
    20161 tcttaaaatc gattgaatct tgtttaaatt taggtataaa agtaaagtta aattgcgttg
    20221 ctataagtgg gtttaatgat gatgagctta aagattttat gtttttaaca gttaaatcac
    20281 caattgatgt aagatttata gagcttatgc cattaggtga ggctaataga gtttataaga
    20341 agggttattt taatgtaaaa gaaatgattg aaaaaatata tggtttatat aaagtcaaaa
    20401 atgatgaaaa aagtacagca gaatattata tgtttaaagg agctaaagga agaataggaa
    20461 ttataactcc attaagctgt tcattttgta acacttgtaa tcgtattaga cttacttcta
    20521 gtggtgcaat aaaattatgt ctacattcaa aagaagaaat agatataaaa ccatttttac
    20581 ataaaccatt gttatttaga gaatctatga aagatataat aaaacaaaaa ccagaaaaac
    20641 atcatttaat agaaaataaa tgtagtgata caaataggcg tatgtatgaa attggaggat
    20701 aagtaatgtt aacacatata aatgaaaaag ggtatgccaa gatggtggac ataagtgaaa
    20761 aagatgatac taaaagaacg gccgtagcta cagctacaat tactcttagt aaggaagcat
    20821 tagaaaaagt aaaaaatggt cagataaaaa aaggagacgt attgtctgta gctcaagttg
    20881 caggtataat gggagctaaa aatacatctt caaacatacc aatgtgccat cagattaaat
    20941 tagttggatg tgatttagaa tttgatgtag atgattctat gtctgctatt aagatatacg
    21001 caacctgtaa atctcttggg aaaactggag tagaaatgga agctttaaat gcatgttctt
    21061 tagcagcact tacaatttat gatatgtgta aagcagttga taaaaaaatg gttataagta
    21121 atatccatct tgtggagaag actggtggaa aatcaggaga ttttaagttc gagtaaatta
    21181 ataatatatt gggttaaaat ttggaggaaa tatggcgaag gtagtgtcaa taaatataag
    21241 tgagaaaaag ggtgtaatta aagttcctgt acaatgtgca gagctaaaaa taaatcatgg
    21301 gatagttgga gatgcacatg caggaaactg gcatcgtcag ataagcttac ttggaaaaga
    21361 aagcatagat aaaatgaaaa tgaaaggctt tgaccaatta aaatatggag attttgctga
    21421 aaatgtaact acagaaggga tagaagtttt ttccctgcct gttggtacaa agttaagaat
    21481 agggcaatgt gaagttgaag taactcaaat agggaaaaaa tgtcacaatg gatgtgaaat
    21541 taagaaattg acaggtgact gtgtgatgcc acgagaagga atttttgtaa aggttctaaa
    21601 agaaggaatt ataaatgtga atgattcaat agatgtaatc taatgaagtc actattaaaa
    21661 tataattata agtaaatact attaagattt aaatatatat tttaagagag aattaatttt
    21721 aataaaatat tttagttata aattggaata
//
LOCUS       DAYAOO010000069        21689 bp    DNA     linear   BCT 12-OCT-2024
DEFINITION  TPA_asm: Clostridioides difficile isolate ST8-SSI-h139-18
            SAMN40601845-rid21577343.denovo.069, whole genome shotgun sequence.
ACCESSION   DAYAOO010000069 DAYAOO010000000
VERSION     DAYAOO010000069.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN40601845
            Sequence Read Archive: SRR28438827
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 21689)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 21689)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-MAY-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-MAY-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002157583.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002157583.1
            Genome Coverage       :: 163x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/11/2024 16:19:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 4,038
            CDSs (total)                      :: 3,963
            Genes (coding)                    :: 3,930
            CDSs (with protein)               :: 3,930
            Genes (RNA)                       :: 75
            rRNAs                             :: 6, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 60
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 33
            CDSs (without protein)            :: 33
            Pseudo Genes (ambiguous residues) :: 0 of 33
            Pseudo Genes (frameshifted)       :: 7 of 33
            Pseudo Genes (incomplete)         :: 25 of 33
            Pseudo Genes (internal stop)      :: 11 of 33
            Pseudo Genes (multiple problems)  :: 8 of 33
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..21689
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN40601845-rid21577343.denovo.069"
                     /isolate="ST8-SSI-h139-18"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Denmark"
                     /collection_date="2018"
                     /collected_by="Statens Serum Institute"
     gene            complement(79..957)
                     /locus_tag="ACGI5H_002785"
     CDS             complement(79..957)
                     /locus_tag="ACGI5H_002785"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430157.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA];
                     GO_function: GO:0050660 - flavin adenine dinucleotide
                     binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="HFG9698482.1"
                     /translation="MRYDIAIIGSGPAGLSAAINAKIRNKTIIMFGNDNLSNKLVKAP
                     SIDNYLGFYDISGDELKDKFKSHIDSMDISIENKRINNIYAMGEYFTIMSGNDMYEAT
                     TVILATGVEYTRPIKGEEEFLGRGVGYCATCDAPLYRNKKVAVIGYNEESKEEANFLS
                     ELTSKTYFIPMYKKDNLMRSSDNLDDSIEVIHDRPVQIDGDKLVNKVSFKENHIEVDG
                     VFVIKDSTAPSALVPGIEIDGIHIKVDNNMKTSIDGCFAAGDCVGKPYSYIKAAGQGQ
                     IAALNAVYYLDKLKRA"
     gene            complement(974..1291)
                     /gene="trxA"
                     /locus_tag="ACGI5H_002786"
     CDS             complement(974..1291)
                     /gene="trxA"
                     /locus_tag="ACGI5H_002786"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420374.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0015035 - protein-disulfide reductase
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin"
                     /protein_id="HFG9698483.1"
                     /translation="MAKVINTSEFRSSVEGSKGVVVVDFFATWCGPCNMLGPVFAELG
                     EEMKDKARFVKVDIDESLEIAQQFNVSTVPTMIIFKDGKPVETLIGFMPKNKIEMQVK
                     SYL"
     gene            complement(1441..2673)
                     /locus_tag="ACGI5H_002787"
     CDS             complement(1441..2673)
                     /locus_tag="ACGI5H_002787"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430155.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing sensor histidine kinase"
                     /protein_id="HFG9698484.1"
                     /translation="MINKNVFTSTKNHLIKMYIIVVGSFLIIFSIFIYSYFRGLTYSG
                     IDSEINDELEYIVSQFKRTSFLNPIRLKDPKDMVYVYEDGRISYYTQNEYFDELLPDR
                     RLDKKNSFFKYTENGYTFRELNVDVGRYQIQIIRNIDSEMNSLRQLTSVLIIGILISV
                     IITYFVAVYLTRKALIPIETAWKNQAKFIQDASHELRTPITIVSSKLESMLKSPESTV
                     NDEVETIATAMKETRRLKKMITDLLSLTKEDSIVKVNLEEIDLEKLLEEISEDYIDIA
                     EFQEKRFVFNSKLKNKVIITDKNKLRQLILIFIDNAFKYTKLGDEIALELKEDIEDEV
                     TLLISDTGIGIKKEEIPLIFDRFFRSENVRNKDLEGSGIGLSIARMISLNLSIDINVT
                     SDVDIGTTFELSIPKKLK"
     gene            complement(2663..3334)
                     /locus_tag="ACGI5H_002788"
     CDS             complement(2663..3334)
                     /locus_tag="ACGI5H_002788"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729560.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000156 - phosphorelay response regulator
                     activity [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HFG9698485.1"
                     /translation="MKVLIVEDNKILLESVVEELSKHFETEKCEDGEEALYLINQNIY
                     DLVILDLMLPNINGFDILKKMRINNIDTPVLILTAKETLDDKVEAFTIGANDYLTKPF
                     YMEELVARVYAILRTNGKIKERNGLEFKSLYLDTLEKRVYIEKEEIKLQNKQFNLLEY
                     FVLNKGSILLKEQIYDRIWGIDSDATIEIVEVYVSNLRKKLSKYGYDKYIKTKRKVGY
                     IFDDK"
     gene            complement(3350..4186)
                     /locus_tag="ACGI5H_002789"
     CDS             complement(3350..4186)
                     /locus_tag="ACGI5H_002789"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454474.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9698486.1"
                     /translation="MNKIVKKSISLMIILTIFIFMLTACEKDEQPDSVDIQTEDKNEI
                     KIDEGNAKVLNIGKSEIINIDEGDKVDTSTKVENNSTFNISNVELIYNEYDENKKIIS
                     SDSKALLDMTLMPGKVAYIECGHKTFVKGVEVYAYEYEAEGKIVYVNLKENTINIRNN
                     NIKLENSSQYEVLSTSELKKVNESNEGITYQVKVKNSSSKDLGNIILKTAEVNENGEY
                     LTVNRVPSYKILKPSEETDIDILCSTKAKSVEIVGYTYDDIKEKANVDIDLKSHKVKI
                     DK"
     gene            complement(4212..4886)
                     /locus_tag="ACGI5H_002790"
     CDS             complement(4212..4886)
                     /locus_tag="ACGI5H_002790"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454475.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein"
                     /protein_id="HFG9698487.1"
                     /translation="MNNNEDRIDKFLELQSKGFKFAEIAQNLKISQSTLRTFLNKKGY
                     KSEKGKYILKDELNYNKSLDNRNLEEEKAKEYEKSKKNTISNRKKVSTKKKISNEKAL
                     SKSVEQIEFNDTGLKNAKPKQNIKPKKDRKINITQEDLDKLCEVYDWYLEVKDYNIKP
                     KKVSNKKDVHIDDEHIDELKTTRIRIDKEIWNDFERLCSNSNFEKHQILTQALKEFMK
                     KYKNLL"
     gene            complement(4900..5628)
                     /locus_tag="ACGI5H_002791"
     CDS             complement(4900..5628)
                     /locus_tag="ACGI5H_002791"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018112775.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA alkylation repair protein"
                     /protein_id="HFG9698488.1"
                     /translation="MMFDRGKWNKLDYNELLEYMMSIQDIKYRDFNKKLIPGTENIIG
                     IRVPNLRKLSKEISQGNWKEFLEVAQDTYYEEVRLQGMVIGNINSNFEETLYYVKRFI
                     PKIDNWSVCDGFCSDLKSMKKYKENMYDILKKYVYSKNPWEIRFALVMFLIYYVDDKH
                     IKEIFEYCNNIQSEEYYVKMGMAWLLSICFIKCEEETFLYIKNNNLDDFTYNKMLQKI
                     IESNRVDLEKKNIIRSMKRKTRRC"
     gene            complement(5755..6444)
                     /locus_tag="ACGI5H_002792"
     CDS             complement(5755..6444)
                     /locus_tag="ACGI5H_002792"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889578.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003824 - catalytic activity [Evidence
                     IEA];
                     GO_function: GO:0051536 - iron-sulfur cluster binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="radical SAM protein"
                     /protein_id="HFG9698489.1"
                     /translation="MDRYSEITNKNQREIVLLKGFPCIWGKCSFCDYIDDNSNLEEEM
                     NKLNLKVLKNVTGKYGVLEVINSGSCFELPKDTLEKIKCIIKEKNIKKLFLESHWSYK
                     NRLKEMREYFEIPVVFKIGVETFDNDFRNNILNKNANFKTPQDVKEYFDSPCIMVGIK
                     GQTKEMIDKDIEIILNTFEKATVNVFINNSSSIKRDEELVKWFVSKYKFLDENPNIEV
                     LYNNTDFGVGD"
     gene            complement(6452..7015)
                     /locus_tag="ACGI5H_002793"
     CDS             complement(6452..7015)
                     /locus_tag="ACGI5H_002793"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420367.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HFG9698490.1"
                     /translation="MKRKICVKTITLIAFGISINIIGAFIAMGLRLPVYLDSIGTIMI
                     ASLLGPKYAVVTGVFGSLISGITFDVYSLYFAPVQISTGLLAGIAFKKNFLRGLKTPL
                     GVLLFAIPTSIISSIISAFLFGGMTSSGSSYIVQILKVLGLGDVFSVFVTQVFTDYGD
                     KLLAVVLVNLGLNAVPKTLKVSLTGGK"
     gene            complement(7017..7985)
                     /locus_tag="ACGI5H_002794"
     CDS             complement(7017..7985)
                     /locus_tag="ACGI5H_002794"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430148.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside hydrolase"
                     /protein_id="HFG9698491.1"
                     /translation="MEKRKVIIDCDPGIDDSLAILLALNSPELEVIGITTCCGNVPAN
                     IGAENALKTLQMCSSLNIPVYIGEEAPLKRKLVTAQDTHGEDGIGENFYQKVVGAKAK
                     NGAVDFIINTLYNHEKVSIIALAPLTNIAKALIKDKKAFENLDEFVSMGGAFRIHGNC
                     SPVAEFNYWVDPHGADYVYKNLSKKIHMVGLDVTRKIVLTPNIIEFINRLDKKMAKYI
                     TEITRFYIDFHWEQEGIIGCVINDPLAVAYFIDRSICKGFESYVEVVEDGIAMGQSIV
                     DSFNFYKKNPNAIVLNEVDEKKFMYMFLKRLFKGYEDIIDSVEGVI"
     regulatory      complement(8086..8129)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00522"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="PreQ1 riboswitch class I; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="preQ1"
                     /db_xref="RFAM:RF00522"
     gene            8495..9124
                     /locus_tag="ACGI5H_002795"
     CDS             8495..9124
                     /locus_tag="ACGI5H_002795"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454480.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HFG9698492.1"
                     /translation="MSIKERRKNEKEEMKKKIMDASIEIINQHGYENLSIRKIATKIE
                     YSPTTIYLYYKDKAEIISDMTNKLYNTVESNAIDIMNNCSSLPIDKQIIEIMTSFIKT
                     LSSEPEMAKSIMHSRMNIIFASENTNNTPSNNGIKMLDKFLSIGIEQGIFKKNIDKSS
                     WMLISALLGFVLCVVENKLYSLHNFSQLIENFLDILVGGLYNENSQQGY"
     gene            9099..9503
                     /locus_tag="ACGI5H_002796"
     CDS             9099..9503
                     /locus_tag="ACGI5H_002796"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430146.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0010181 - FMN binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="FMN-binding protein"
                     /protein_id="HFG9698493.1"
                     /translation="MKIRNKATNKKKKYVKISIALFFVFICIIIVIVSNLKPENLVVK
                     DIDINNVKNGIYTGSADNNLVKATVSVEVNNGKIQNINILKHDHLLGKPAEKITTSII
                     KQQSLDVDAITSATYSSNTIRKAVENALRKGE"
     gene            9506..9982
                     /locus_tag="ACGI5H_002797"
     CDS             9506..9982
                     /locus_tag="ACGI5H_002797"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889569.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flavodoxin domain-containing protein"
                     /protein_id="HFG9698494.1"
                     /translation="MNTIIIYSSKYGCTKDCANILKNKLSDNVTIVDINNNNNKIELS
                     KFDKIIIGSSIYVGSVSKKIQVLCNDNVELLNKKQVGIFLCCGFSEQADKYLKSNFPS
                     SLLESANAIGIFGSEARLEKMKFLDKLIMKAVSKGNYDSFRISQDNIDNFLINLNS"
     gene            10554..11219
                     /locus_tag="ACGI5H_002798"
     CDS             10554..11219
                     /locus_tag="ACGI5H_002798"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889567.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF969 domain-containing protein"
                     /protein_id="HFG9698495.1"
                     /translation="MIKLIGILIVVIGFILKIDTLFTVLLAGVATGIVAGLDFNQIFT
                     ILGDSFVSNRGVSLFILTLPVIGVLERYGLRQRAVSLIEKLKRLTTGKVLTIYMIARQ
                     IAGALSIRMSGHPQFVRPLVNPMAQAAGLSNSDELKESDEEAIKALSAASENYGNFYG
                     QNLFAGSSGVLLIASTLTQFGYNVTGLNIVKASTIMAVIALVVATIQFTLYDKKLNKS
                     HKK"
     gene            11241..12173
                     /locus_tag="ACGI5H_002799"
     CDS             11241..12173
                     /locus_tag="ACGI5H_002799"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430140.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF979 domain-containing protein"
                     /protein_id="HFG9698496.1"
                     /translation="MQNFINISLEIFYALMGFLMIVIAYKSFTTINNNKKYGTSLFWI
                     LISLPFIFGRLIPANIIGIILILSSLLTLSKQVVFAKYEEPDENFGKEQADKLKNKIF
                     IPSLILAFAAVVVAMSLSNFDNSSQFAIGVGSIIALISALIITKAKPATSVQDGSRLL
                     QQMGPASMLPQLLVALGALFTQAGVGEVISTMISGVVPADSRLFGVIAYVLGMVIFTM
                     IMGNAFAAFSVITAGIGIPFVLSQGGNPAIIGALALTAGYCGTLLTPMAANFNIVPAA
                     LLECKNDYIVIKYQAPVALVLIIAHILVMYFLGF"
     gene            12194..12835
                     /gene="pcp"
                     /locus_tag="ACGI5H_002800"
     CDS             12194..12835
                     /gene="pcp"
                     /locus_tag="ACGI5H_002800"
                     /EC_number="3.4.19.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420360.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005829 - cytosol [Evidence IEA];
                     GO_function: GO:0008234 - cysteine-type peptidase activity
                     [Evidence IEA];
                     GO_function: GO:0016920 - pyroglutamyl-peptidase activity
                     [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pyroglutamyl-peptidase I"
                     /protein_id="HFG9698497.1"
                     /translation="MKILLTGFDPFGGEPINPAQEAVERVNNNINGAEIIKITIPTVM
                     TKSVEAIDKAIQEHNPDIVISVGQAGGRFDITPERVAINIDDFRIKDNEGNQVIDTII
                     KEDGEPAYFSKLPVKAMVKHMNENKIPASVSNTAGTFVCNHVMYGILYMIDKKYPNIR
                     GGFIHIPYTTSQVIDKKNTPFMSLEEIVKGLELAIEACIIYKEDVKEIGGEIS"
     gene            complement(12955..13287)
                     /locus_tag="ACGI5H_002801"
     CDS             complement(12955..13287)
                     /locus_tag="ACGI5H_002801"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420359.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="winged helix-turn-helix transcriptional
                     regulator"
                     /protein_id="HFG9698498.1"
                     /translation="MSIDCISNTDLSETGFSYTLSLISGKYKMIILYCLVEFEVVRYN
                     ALKRYINTISYKTLSLSLKELEADNLIIRTEYPQIPPKVEYSLSERGKSLIPILDAMC
                     EWGERNRP"
     gene            13553..14173
                     /locus_tag="ACGI5H_002802"
     CDS             13553..14173
                     /locus_tag="ACGI5H_002802"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454488.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0009055 - electron transfer activity
                     [Evidence IEA];
                     GO_function: GO:0010181 - FMN binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="flavodoxin family protein"
                     /protein_id="HFG9698499.1"
                     /translation="MKVLLINGSPNQYGCTYTALNEITKVLSKHDIKTEILYLGKETI
                     PGCISCASCFETGKCIRNDKVNELIEDLDNIDGIIIGSPVYFSSATGQLTSFLDRLFF
                     IAGSRMATKLGASVVSCRRGGASATFDQLNKYFSISNMPIVSSQYWNQVHGFTPEDVM
                     KDEEGLQTMRTLGENMAWLLKCISAGKKAGIKEPQYEETIMTNFIK"
     gene            complement(14498..15322)
                     /locus_tag="ACGI5H_002803"
     CDS             complement(14498..15322)
                     /locus_tag="ACGI5H_002803"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729568.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TraX family protein"
                     /protein_id="HFG9698500.1"
                     /translation="MDFFKKGISGFTIKILALIFMTFDHIAAFMPQTMQIPIWFHWVG
                     RISAPLFIFMAVEGFYHTSNRKKYISRLYIWSVIMAIGNQIINNVFSHPEGAIIINNT
                     FSTLFLIAIYLQAIEFIKKFRKEKEIKYFIIGLLMIIIPIILGIFTVALLFKVTNRVI
                     ALFMILVPVPFLVEGGPIWIILGIIFYLCRGKKFSLSICYVLMCIFIFTTMSNGDYSL
                     KNSILQNYQWMMIASLPLMLLYNGEKGKSMKYLFYLYYPIHVYILYILGIYLINGF"
     gene            complement(15333..16736)
                     /locus_tag="ACGI5H_002804"
     CDS             complement(15333..16736)
                     /locus_tag="ACGI5H_002804"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729569.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HFG9698501.1"
                     /translation="MKWKITRNFIFTIVFVAISVVIINIISILYVISTNSFFKVVDSG
                     NNPEEFARSFEKDLYEKDGEFKLSKIGAEKLEKSNSWIQVLNDLGEEVYGVNVPKDTP
                     KKYTPFQMVNNYKYIETKYVNFVLEKYLNKKHLNIIVGIPSRDISRIILTYSQNNIKK
                     TLNKVIIITLVIDSVVALGVGYLFSRKLTKPISSVLWSIETMANGNYSLYLKDRGIYE
                     EVFKNINMLADTLRVNEVERKENEELREEWLANITHDIKTPLASIQGYAEIINDKDYE
                     FEEDEIQEYTEIIYNKSKYIKDLVDDLNLSTRLKNNTIVLDKKKINLVSLVRDIIIDI
                     LNDNRYKNRNIEFESNEDLIEVYVDSILFRRAITNLIFNSIVHNSEGTLISVEIVKKD
                     NIEIIIKDDGIGISKSDLKHIFKKYYRGTNTGEMHKGSGLGMAISKEIIEIHKGKIYV
                     SSEIGIGTKIIIEIKQN"
     gene            complement(16740..17465)
                     /locus_tag="ACGI5H_002805"
     CDS             complement(16740..17465)
                     /locus_tag="ACGI5H_002805"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420352.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000156 - phosphorelay response regulator
                     activity [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HFG9698502.1"
                     /translation="MENRVLIIDDEVEILKLLETVLKKEGLNNIYTAKTKKEGLELFK
                     SINPDLIVLDIMLPDGEGYDICKEIRKTSNSPIIFLSAKTEELDKLLGLAIGGDDYVT
                     KPFSPKEVAFRVKAHLRRLSYFSDAQNESKNLNNNEEKIISFGPYILNESRAELIKDG
                     KSIGLSAKELKILSLFAHNQNQIISKEKLWDKVWGEDYVGFDNTIMVHIRKIREKLED
                     NPSKPEYILTIKGLGYKLAVKED"
     gene            complement(17577..18350)
                     /locus_tag="ACGI5H_002806"
     CDS             complement(17577..18350)
                     /locus_tag="ACGI5H_002806"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896816.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HFG9698503.1"
                     /translation="MMYLVKAEMIKILKSKSVWIIWLFLIFFGFFLIRKFDVLDTYAD
                     IFYKIEGSIPLIGLIMFIITSGNYIKEYDSNMTGLINTTKKGKKSVVLSKLVANGLIL
                     SIINISFILLVGIRGFSFFDFKNLNESIHNLWYFGNSNLNLTVIQMYIIVILTTIFAS
                     FIFAQIGLTLSSIFKSAVIPFILGGLIMAIPYFSVGFIPDKAIKFMSVTPNWIMMSQQ
                     MVKYNVPSILIVFSIVISIILMIVLTKITYENFTSSKRF"
     gene            complement(18356..19243)
                     /locus_tag="ACGI5H_002807"
     CDS             complement(18356..19243)
                     /locus_tag="ACGI5H_002807"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889563.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HFG9698504.1"
                     /translation="MNKLEIENLSKIYGKKVANDKITVTLENGVYGLLGPNGAGKSTL
                     MKQITTLIKPDEGQILYNGEDIFKMDADYRNILGYLPQEFGVYKNFTAKEFLQYIGAL
                     KGLRGKYLNSKIGELLDLVGLYDVRNKSIGKFSGGMKRRVGIAQVLLNDPKIIVLDEP
                     TAGLDPQERARFRNLIAKMSRDKIIILSTHIISDIESVAKETIMIKDGKLLMKGTHKD
                     ILSHMENKVYNVQVKNECEVDDIQSKYKVVSIQSDIDSVVLRIVSEDIPSEDNIQPVQ
                     AKFEDVYMFYFDLEDAREV"
     gene            complement(19257..20279)
                     /locus_tag="ACGI5H_002808"
     CDS             complement(19257..20279)
                     /locus_tag="ACGI5H_002808"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893219.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9698505.1"
                     /translation="MVNWEIKKLAKSKSMFISLGILVLILMISIFITPVLETESYYID
                     KEKGRIEDTRSGIDVGNEKFQNKINVLKQFSNQTDTGEFSKKIELMSKKKLDNLSVNE
                     YKDISFWKVFNYRVTNSLINVGMLIIISIIISNIYVDEVVTSVKDIILSSKEKKKALK
                     SKIFVALLVPLVIYSVYLMGIFIITCMQQGVPVNGDLESFRIVDNVVALKTNLSITKY
                     VILNIGIELLMFEGWAMIAIFGSFISKSSISSISFFIFIISITKIMSVIHILPKKLLS
                     VVSNVNYYDLIFGFNKIIGNYLGDIMIFKVNIDIVNIAIGLLMAILIGAMSLCFLVIK
                     SDYISR"
     gene            20854..21030
                     /locus_tag="ACGI5H_002809"
     CDS             20854..21030
                     /locus_tag="ACGI5H_002809"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9698506.1"
                     /translation="MFIGEIDKCTHILTAYISSSYDYCNFLDTQLDDFISEYGETVVE
                     TCLHQVLLLVSRYN"
BASE COUNT         7541 a         3398 c         2319 g         8431 t
ORIGIN      
        1 aaaaactgtc ttgaaataat aaaattattt caagacagtt ttttataaat atctttaaaa
       61 agttaatcaa tataaatatt aagccctctt taatttatct aaatagtaaa cagcatttaa
      121 agctgctatt tgcccttgac cagctgcttt tatataagaa tagggttttc caacacaatc
      181 tccagcagca aagcatccat ctatactagt cttcatatta ttgtcaactt taatatgaat
      241 gccatcaatc tctattccag gaaccaatgc acttggagcc gtactatctt ttataacgaa
      301 tactccatca acttcaatgt ggttttcttt aaaagatact ttgtttacaa gtttatctcc
      361 atctatctgt actggtctgt catgtataac ttcaatagaa tcatctaggt tatctgaact
      421 tctcataaga ttatcttttt tgtacatagg tataaaataa gtctttgaag tgagttcact
      481 taaaaaattt gcttcttctt tagattcttc attatatcct ataactgcta cctttttatt
      541 tctataaagt ggtgcatcac atgtagcaca gtagcccaca cctcttccta gaaattcttc
      601 ttcacccttg attggtctag tatactctac cccagttgca aggattacag tagtagcttc
      661 atacatatca tttccagaca ttattgtaaa gtattctccc atagcataaa tattatttat
      721 tcttttattt tcaattgaaa tatccatact atctatatgt gatttaaact tgtcttttaa
      781 ttcatcacca cttatatcat aaaaacctaa ataattatct attgaaggag ctttaacaag
      841 cttattactt aaattatcat taccaaacat gataattgtt ttatttctta tttttgcatt
      901 tatagcagca gacaatccag ctggaccact gccgattata gctatatcat atctcataat
      961 actcacccat tttttataaa tatgatttta cttgcatttc aattttgttc tttggcatga
     1021 atccaattaa agtttctact ggttttccat ctttaaatat aatcatagtt ggtactgtag
     1081 atacattgaa ttgttgagct atttctaaac tctcatctat atcaactttt acaaatctag
     1141 ctttatcctt catctcttca cctaattctg caaatacagg tcccaacatg ttacaaggtc
     1201 cacaccaagt tgcaaagaaa tcaactacaa ctactccctt actaccttca acactacttc
     1261 taaattcaga tgtatttata acttttgcca tttttaaatc ctcctattaa actttattat
     1321 ccctatataa ttatactatg aaatttataa atataaattt acttttataa ggtcttttta
     1381 tattttatac taattagtat acccattctt catttctaaa aacaattttt tatattttta
     1441 ttattttaac ttttttggta ttgacaattc aaatgtagtt ccaatatcta catcagaagt
     1501 tacatttata tcaatagata agtttaaact aatcatgcga gctattgaaa gtcctattcc
     1561 agaaccttct aaatctttat ttcttacatt ttcacttcta aaaaatctat caaatataag
     1621 aggtatctct tcttttttta tgcctatacc agtatcactt ataagtaaag ttacctcatc
     1681 ctctatatct tctttcaatt ctaatgctat ctcatcaccc aattttgtat acttaaaggc
     1741 attatcaatg aaaattaata taagttgtct taatttattt ttatctgtta ttataacttt
     1801 attcttcagt ttagaattaa acacgaatct tttttcctga aactcagcaa tgtcaatata
     1861 gtcttctgat atttcttcca ataacttttc taaatctatt tcttctaaat taactttaac
     1921 aatagagtcc tctttagtaa gagacaataa atcagttatc atttttttaa gtcttctagt
     1981 ttccttcatt gcagtagcta ttgtttcaac ttcatcattt actgtacttt ctggggattt
     2041 taacatactt tctaattttg atgaaactat tgttattggt gttcttaatt catgagaagc
     2101 atcttgtata aacttagctt gatttttcca tgctgtttct attggaatta aagcttttct
     2161 agtgagatat acagccacaa agtaagtaat tattacagaa attaatattc caattataag
     2221 aacagatgta agctgtctta aagaattcat ctcagaatct atatttctaa ttatctgtat
     2281 ttggtatcta cctacatcta catttaattc tctaaaagta tatccatttt ctgtgtattt
     2341 aaaaaacgaa ttttttttat ctagtcttct atctggaagt aactcatcaa aatattcatt
     2401 ttgagtatag taacttatcc ttccatcttc atatacatac accatatctt taggatcttt
     2461 gagtcttatt gggttcaaaa atgaagttct tttaaattga gagactatat attcaagttc
     2521 atcatttatc tcactatcaa ttccactata tgtaagtccc ctaaaatatg agtatataaa
     2581 tatagaaaag attattaaaa aactacctac tacaataata tacattttta ttaaatgatt
     2641 tttagtactg gtaaatacat tcttatttat catcgaatat atatcctacc ttacgtttag
     2701 ttttaatata tttatcatat ccatatttac ttagcttttt tcttagatta cttacatata
     2761 cttccactat ttcaatagtt gcatctgaat caattcccca tattctatca taaatctgct
     2821 cttttaataa aattgaacct ttatttaata caaaatactc aagcaagtta aactgtttgt
     2881 tttgaagttt tatttcttct ttttcaatat acactctttt ttctagtgta tctaaatata
     2941 aagatttaaa ttctaatccg tttctttctt ttatctttcc attagtcctt aatatagcgt
     3001 ataccctagc tactaactct tccatataaa aaggttttgt caaataatca ttagctccta
     3061 tagtaaatgc ttctactttg tcatctaatg tttcttttgc tgtcaatata agtacaggtg
     3121 tatctatatt attaattctc attttcttta ggatatcaaa tccatttata ttaggaagca
     3181 ttaagtctaa aatgactaaa tcatatatat tttgatttat taagtataaa gcttcttctc
     3241 catcttcaca cttttcagtt tcaaaatgct tgctaagttc ttctactaca ctttctaaaa
     3301 gtatcttatt atcttcaact attaaaacct tcataagtat cccctacctt tatttgtcta
     3361 tcttaacttt atgagatttt aagtcaatat ccacattggc tttttctttt atatcatcat
     3421 acgtatatcc cactatttca acactttttg cctttgttga acacaatata tctatatctg
     3481 tctcttctga aggctttaaa atcttatatg atggtacacg atttactgtt aaatattctc
     3541 cattttcatt aacttctgct gtcttaagaa taatatttcc taaatctttt gatgatgaat
     3601 tttttacttt tacttgatac gtaattccct catttgattc atttactttt ttaagttctg
     3661 atgtagatag cacctcatac tgactactat tttctagctt aatattatta tttcttatat
     3721 taatagtatt ttcttttaaa ttaacataca caatcttacc ctctgcctca tattcatatg
     3781 cataaacttc tacacccttt acaaaagttt tatgcccaca ttctatgtaa gcaactttcc
     3841 caggcattaa agtcatgtcc aacaaagcct tactatccga agatataatt tttttattct
     3901 catcatattc attatatatc aattcaacat tggatatatt aaatgttgaa ttattttcta
     3961 cctttgttga tgtatctact ttatcacctt catctatatt tataatttct gattttccta
     4021 tattcaatac ttttgcattt ccctcatcta tttttatctc atttttatct tctgtttgaa
     4081 tatcaactga atcaggctgt tcatcttttt cacatgctgt caacataaaa ataaatattg
     4141 ttaatataat cattagagaa attgattttt ttactatttt attcatatta agcacctcat
     4201 atagtagtat tttatagtag atttttatac tttttcataa attctttcaa tgcctgtgta
     4261 agtatttgat gtttttcaaa attcgaatta ctacataatc tttcaaaatc attccatatt
     4321 tctttatcta tacgtattct tgttgttttt aattcatcta tgtgttcatc atctatatgt
     4381 acatcttttt tattagatac ttttttaggc tttatattgt aatcttttac ttctaaatac
     4441 caatcatata cttcacaaag cttatctaaa tcttcttgag ttatatttat ttttctatct
     4501 ttcttaggct taatattttg ttttggcttt gcatttttta aacctgtatc attaaactca
     4561 atttgttcaa cacttttact taaagccttt tcattagaaa tctttttttt ggtgcttact
     4621 ttttttctat tacttatagt attcttttta cttttttcat actccttagc tttctcttct
     4681 tccaagtttc tattatccaa acttttatta taatttaatt cgtcttttaa tatgtattta
     4741 cctttttctg acttatatcc ttttttattt aaaaaagttc ttaaagtact ttgactaatc
     4801 tttagatttt gagctatctc tgcaaattta aatcctttgc tttgaagttc taaaaatttg
     4861 tcaattctgt cttcattgtt attcattaat attcctccgt caacatcttc ttgtctttct
     4921 tttcatactt cttattatat tcttcttttc taaatctact ctatttgatt caattatttt
     4981 ttgtagcatt ttattataag tgaaatcatc taaattatta ttttttatat agagaaaagt
     5041 ttcctcttca catttaataa aacaaattga tagcaaccat gccataccca ttttaacata
     5101 atattcttca ctttgtatat tattacagta ttcaaatatt tctttaatat gtttatcatc
     5161 aacataatat attaaaaaca taactaatgc aaatctaatt tcccatggat tctttgaata
     5221 aacatatttt ttaagtatat catacatatt ttctttatat tttttcatag actttaaatc
     5281 agaacaaaat ccatcgcaaa ctgaccaatt atcgatttta ggtataaatc tttttacata
     5341 gtataaagtt tcttcaaaat tactatttat attgccaatt accatacctt gtagcctaac
     5401 ttcttcatag tatgtatcct gtgctacttc taaaaattcc ttccaattcc cttggcttat
     5461 ttcttttgat aactttctta aattaggaac tctaatacct attatatttt ctgttccagg
     5521 tataagcttt ttattaaaat ctctatattt tatatcttgt atagacatca tatattctaa
     5581 aagttcatta taatccaatt tattccattt tcccctatca aacatcattt aattgctcct
     5641 taattccttt tttcttattg taacataaaa ctctacaaaa aaagcttcta actattagaa
     5701 gctttttcaa aaacataaga aacttttcaa ttttaaattt aaactaaatt aatgctaatc
     5761 tcctacacca aagtctgtat tattgtataa aacttctata tttggatttt catccaagaa
     5821 tttatactta ctaacaaacc atttcactaa ctcttcatct ctttttatac tagaagaatt
     5881 atttataaaa acattcactg tcgctttttc aaaagtattt aggataatct ctatatcttt
     5941 atctatcatc tcttttgttt gtccttttat tccaaccata atacaaggtg aatcaaaata
     6001 ttcttttaca tcttgtggag tcttaaaatt tgcattttta tttaaaatat tatttctaaa
     6061 atcattgtca aaggtttcaa ctccaatttt aaataccaca ggaatttcaa aatactctct
     6121 catttcctta agcctatttt tgtaagacca atgactttct aaaaataatt tttttatatt
     6181 cttctctttt ataatacact ttattttttc taaagtatcc ttaggtaatt caaaacagct
     6241 tccagaattt atgacttcaa gaactccata tttcccagtt acgtttttta aaacctttag
     6301 atttaattta ttcatctctt cttctaaatt agaattatca tctatataat cacaaaaaga
     6361 acactttccc catatacaag gaaatccttt aagcagaaca atttctcttt gatttttatt
     6421 tgttatctca ctatatctat ccattttcta tctattttcc tccagtcaat gataccttta
     6481 aagtttttgg aactgcattt aatcctaaat tcactaaaac aactgctaac agcttatctc
     6541 cataatcagt aaatacttgg gttacaaaca cactaaaaac atcccccagt cctaacactt
     6601 tcaagatttg cactatatat gatgaacctg aagaggtcat acctccaaat aaaaatgctg
     6661 aaattattga acttattata gatgttggaa tggcaaataa aagtactcct agtggagttt
     6721 ttaaacccct taaaaaattc tttttaaatg ctattccagc aagtaatccg gttgatattt
     6781 gaactggtgc aaaatagaga gaatacacat caaacgtaat tccacttatt aaacttccaa
     6841 acacacctgt aacaacagcg tatttaggtc ctaaaagtga agctatcatt atagttccta
     6901 ttgaatctaa gtatacaggt aatcttaatc ccatagctat aaaagcgcct attatattta
     6961 tagaaatacc aaaagctata agtgtaatag tttttacaca tatttttctt ttcacactat
     7021 atcactcctt ccacagagtc tataatgtct tcataacctt taaaaagcct ctttaaaaac
     7081 atgtacataa atttcttctc atcaacttca tttagaacaa ttgcattagg atttttttta
     7141 tagaaattga aagaatccac tatagactga cccatagcta ttccatcttc tacaacttct
     7201 acatatgatt caaatccttt acatatactt ctatctataa agtatgctac tgctagaggg
     7261 tcatttatca cacagccaat tattccctcc tgttcccaat ggaaatcaat ataaaatcta
     7321 gttatttcag ttatatactt tgccatcttc ttatcaagtc tatttataaa ctcaataata
     7381 ttaggagtaa gtacaatttt tctagttaca tctaaaccta ccatgtggat ttttttagat
     7441 aaattcttgt aaacataatc tgctccatgt gggtctaccc aataattaaa ctctgctact
     7501 ggagagcaat ttccatgaat cctaaatgct cctcccatag atacaaactc atcgagattt
     7561 tcaaatgctt tcttatcttt aataagtgct ttagctatat ttgtaagtgg tgcaagtgct
     7621 attattgata ctttttcatg attatataaa gtatttatta taaaatccac tgctccattt
     7681 tttgctttag ctcctacaac cttttgataa aagttttctc caataccatc ttctccatgt
     7741 gtatcttgag ctgttacaag ttttcttttt agtggtgctt cttctcctat atatactgga
     7801 atatttagtg aagaacacat ttgaagtgtt tttagtgcat tttctgcacc tatatttgct
     7861 gggacatttc cacaacatgt ggtaattcca attacttcta gctctggtga gtttaaagcc
     7921 agaagaattg ccaaagaatc atcaattcct gggtcacaat caattattac ttttctcttt
     7981 tccatttttt atcctccttg atttgtggtc gaggagaact acacatcttt tttccacttt
     8041 caaaaaggtg tgtctaaggg tattaattat atactgccac tatataattc cttagttttt
     8101 tatacttgga gttctcgaac aagtacagat gtaaaatcat atttttaggc tacttactat
     8161 aagactctta aaaactatag accgttaaaa aatttttaaa catctgattt aatagctata
     8221 aaataaattt tatagcataa aagaatttat tatattttaa tgtatcttat taaagtttat
     8281 ttagaattat gaaccaactt taataagatg tggcgcattt aaaccgatta ttattataca
     8341 ataatatctt aaatattaca attaataaca ttaatttatt atccataaaa atatattaac
     8401 ttatattatt taataattta ttgacagtat taaaattaaa ttatacaata acagtgtaaa
     8461 ttaacttaac accgttaagc aaagaggtga ttatatgagt atcaaagaaa gacgtaaaaa
     8521 tgaaaaagaa gaaatgaaga aaaagattat ggatgctagc atcgaaatta taaaccaaca
     8581 tggatatgaa aatttatcaa taagaaaaat tgctacaaaa atagaatatt ctccaactac
     8641 aatttatctt tactacaaag acaaagcaga gattatcagc gatatgacca ataaacttta
     8701 taacacagta gaaagtaatg ccattgacat tatgaataat tgctcatcac taccaataga
     8761 taaacaaatc atagaaatta tgactagctt tataaaaact ctttctagtg aaccagagat
     8821 ggcaaaatct atcatgcata gtagaatgaa tattatattt gcatctgaaa atacaaacaa
     8881 tacgcctagc aataatggta taaaaatgct tgataaattc ctttccattg gaattgaaca
     8941 aggaatattc aaaaaaaata tagataaaag ctcatggatg cttataagtg cattgttagg
     9001 attcgtttta tgtgttgttg aaaataaact atattcttta cataattttt ctcaacttat
     9061 agaaaatttc ttagatattt tagtgggagg actttacaat gaaaattcgc aacaaggcta
     9121 ctaataaaaa gaaaaaatat gtaaaaatat ctattgctct attctttgta tttatatgca
     9181 ttattattgt aattgtaagc aacttaaagc cagaaaactt ggtagtaaaa gatatagata
     9241 ttaataatgt taaaaatggc atttatactg gaagtgctga taataacttg gtaaaagcta
     9301 ctgtgtctgt tgaagttaat aatggtaaaa tccaaaatat taatatctta aaacacgacc
     9361 atcttttagg taaacctgct gaaaaaatta caacaagtat tattaaacaa cagtctttag
     9421 atgtggatgc tataacttct gcaacttata gcagtaatac tatacgaaaa gctgtagaaa
     9481 atgctttaag aaagggagaa taattatgaa tactattatt atatattcaa gtaaatatgg
     9541 ttgtacaaaa gactgtgcaa atatactaaa aaataaacta tcagataatg tcactattgt
     9601 tgatattaat aataataata ataaaattga gttatcaaaa tttgataaaa ttattattgg
     9661 aagttctata tatgttggtt cagtttcaaa aaaaatacag gtgctatgta atgataatgt
     9721 agagttatta aacaaaaaac aagttggcat tttcctttgc tgtggctttt ctgaacaagc
     9781 agataaatat ttaaaatcaa attttccatc atccttatta gaaagtgcaa atgctattgg
     9841 aatttttggt agtgaagctc gattagaaaa aatgaaattt ttagataaac ttattatgaa
     9901 ggctgtttca aaaggtaatt atgacagttt tagaatatca caggataata tagataattt
     9961 tttaataaat cttaatagct aaaataaagc taattatttc tatgataaat tcttttattt
    10021 ataagtaata ttgctcaaaa tagtctttaa actttatcaa aattttattt ttcttagtga
    10081 aatctaatga aactagcact taatatatgc tttattaatc ataacaaata tgttttatta
    10141 atcataacaa aaagagagtg tctaatgaac taaaaaattc attagacact ctctttttgt
    10201 atgaaatcaa atatattttt atcatttcaa cagagaaaaa tacacttgtc tctatgtttg
    10261 gcacattctc tttttataat ataatgttta atttaaaact actatttcaa atattgacat
    10321 atacttaaac tatagactta caaaatcaat tcatattagc ttaaaatata atctttgtta
    10381 ttcaaattcc tatacacaac cattatttac tttgatactt taaaacatct tccctatttt
    10441 ttattaaatt ttataataat agtcctatta acgcaaatac tataaaaaga gtttaacttt
    10501 atccattaaa taaatttaaa ttaaaacata tagaaatgga aggagaacaa tttatgataa
    10561 aactaatcgg tatattgata gttgtaattg gatttatact taaaattgac acactattta
    10621 ctgtattatt agcaggagtg gcaacaggaa ttgttgcagg attagatttt aatcaaattt
    10681 ttacaatttt aggagattct tttgtctcaa acagaggtgt atcattattc atattaacat
    10741 tgccagtaat cggtgtatta gaaagatatg gtttaagaca aagagctgtt tctttaatag
    10801 aaaaattaaa aagacttaca acaggaaaag tacttactat atacatgata gctagacaaa
    10861 tagctggtgc tctatcaata agaatgagtg gacatcctca atttgtaaga ccacttgtta
    10921 atcctatggc acaagctgct ggtttaagta atagtgatga actaaaagaa tcggatgaag
    10981 aagccataaa ggcattatct gctgcatcag aaaactatgg aaatttttat ggtcaaaact
    11041 tatttgcagg tagtagtgga gtattactta tagcatctac tctgactcaa tttggataca
    11101 atgtaactgg acttaatatc gtaaaggcta gtactattat ggcagtaata gcacttgtag
    11161 tggctacaat ccagtttacc ttatatgata aaaaattaaa caaaagtcat aaaaaatagt
    11221 tttatttagg aggaataaaa atgcaaaatt ttataaacat atcattggaa atcttttacg
    11281 cactaatggg atttttaatg attgttatag catataagtc ttttactacc ataaataaca
    11341 ataagaaata tggtacatca ttattttgga tacttatatc actgccattc atatttggta
    11401 gattgattcc agccaatata ataggaataa tattaatatt atctagttta ttaacacttt
    11461 ctaaacaagt tgtatttgca aagtatgaag aaccagatga aaattttgga aaagaacaag
    11521 cagacaaact taaaaataaa atatttatac catcattaat attagcattt gctgcagtag
    11581 tagtagctat gagtctttct aattttgata attcttctca gtttgcaata ggtgtgggtt
    11641 caataattgc attaatatca gcccttataa taactaaggc aaaacctgct acatcagttc
    11701 aagatggctc aagattactt caacaaatgg gacctgctag tatgttacca caacttttag
    11761 ttgcattggg agctttattt actcaagccg gagtcggtga agttatttca accatgatat
    11821 ctggtgtagt ccctgctgat agcagattat ttggtgttat agcttatgta ttaggtatgg
    11881 ttatatttac catgataatg ggaaatgcat ttgccgcatt ttcagtcata acggcaggaa
    11941 ttggtattcc ttttgtattg tctcaaggtg gaaatcctgc tataattgga gcattagcat
    12001 taacagcagg atattgtgga actctactta ctccaatggc tgctaatttt aatatagttc
    12061 cagcagcctt gctagaatgt aaaaatgatt atattgttat aaaatatcaa gctccagttg
    12121 ctttggtatt aattatagcc cacatattag taatgtactt tttaggattt taatataatt
    12181 aggaggtaaa ataatgaaaa ttttgttaac aggatttgac ccatttggcg gagaaccaat
    12241 aaacccagct caagaagcag ttgaaagggt caataataat ataaacggtg cagaaatcat
    12301 aaagataact ataccaacag ttatgacaaa atctgttgaa gctatagata aagctattca
    12361 agagcacaat ccagatatag taatatcagt tggacaagct ggaggtagat ttgacattac
    12421 acctgagaga gttgctataa atatagatga ttttagaata aaagataatg agggtaacca
    12481 ggttatagat actattataa aagaagatgg tgaacctgca tatttttcaa aattgcctgt
    12541 aaaagctatg gtaaaacata tgaatgaaaa taaaattcca gctagtgttt caaacactgc
    12601 aggaacattt gtttgcaatc atgtgatgta tggaattctt tatatgatag acaagaaata
    12661 tcctaatata aggggtggat ttatacacat cccatataca acttcacaag taatagataa
    12721 aaaaaataca ccattcatgt ctttagaaga aatagtaaaa ggcttagaat tagctataga
    12781 agcttgtatt atatataaag aagatgtaaa agaaattggt ggtgaaattt cataataaat
    12841 tttttagtat ttttataaat taaaaatact aactattaat ttaaatatag actgtgagta
    12901 gattattcaa acaattttac tcacagtctt tttatggtat ctacagatac aaaattaagg
    12961 tctattcctc tctccccact cacacattgc atctaaaatt ggaatcagag attttcccct
    13021 ttctgataga ctatattcta ccttaggagg tatttgagga tattcagtac gaataatcaa
    13081 gttatctgct tctaattctt ttaatgataa actcaaagtt ttataggaga tagtatttat
    13141 ataacgtttt aatgcattat atcttacaac ttcaaattct acaagacagt aaagaattat
    13201 catcttatat ttaccactaa tcagtgaaag tgtataacta aatcctgttt cacttaaatc
    13261 tgtatttgat atacagtcta tactcatata ttacactctc cttttggtta gtattgaaca
    13321 aaaatgtgcg tacttgtttt tagaataatt tataataaaa ttatagtgta agaataattg
    13381 aaagtcaatt ttataatagg aggtgtattt actaaaaaaa aagttatttt aaataggatt
    13441 ctaagattag acatttctat ataaattgat aatattcatg aaaatcctat tttataaaaa
    13501 ataatgtctc ttagaaaatc tattaaataa aattcattgg aggaaattta taatgaaagt
    13561 tttattgata aacggtagcc caaaccaata tggatgtact tatacagcac taaatgagat
    13621 tactaaagta ttgagtaaac acgatattaa aacagaaata ctgtatttag gtaaagaaac
    13681 aatcccagga tgtattagtt gcgcatcctg ttttgaaact ggaaaatgta ttcgaaatga
    13741 taaagttaat gaattgattg aagatctgga taatattgat ggtattatta ttggttctcc
    13801 tgtttacttt tctagtgcaa ctggtcaatt aacttctttt cttgaccgtc tatttttcat
    13861 agctgggagt cgcatggcta caaaattagg tgcttcagtt gtgtcatgta gacgtggtgg
    13921 tgcaagtgca acatttgacc aactaaataa atatttttca atcagcaata tgcctattgt
    13981 atcatcacag tattggaacc aggtacatgg ctttactcca gaggatgtta tgaaggatga
    14041 agaaggatta cagactatgc gaactctagg agaaaacatg gcatggcttc ttaagtgtat
    14101 atcagcaggt aaaaaagctg gaattaaaga accacaatat gaagaaacaa ttatgactaa
    14161 ttttataaaa taaataaaaa atgtactaat attaattaaa acaaaacact aatttataaa
    14221 taaaataagc ataaatgtag gataaaaagc actaaaacag aggtattgaa ttttatatca
    14281 aacctctgtt ttattattac attaataacc aaaccatgta taacatcata tatttctaaa
    14341 taaattataa tattatattc taatgttatt gaaattacaa taactgaatt tctgctcata
    14401 aatttaaata ttctacaaat ctcatctaaa taacaatttt aatagaccta aaacaatcct
    14461 catactgttc attttgtatt aaaaatatca cttacaatca aaaaccattt attaagtata
    14521 ttcctaagat atacaatata tatacatgga ttggatagta taaataaaat aaatacttca
    14581 tactcttccc tttttctcca ttgtaaagta acattaaagg tagagaagca atcatcatcc
    14641 attggtaatt ttgtaaaata gaatttttta aactataatc tccatttgac attgttgtaa
    14701 atataaatat acacattaaa acataacaaa tactcaaact gaacttttta cctctacaca
    14761 aataaaaaat aatcccaagt ataatccaaa ttggtccacc ttctactaaa aatggtactg
    14821 gtaccaaaat cataaataaa gcaataactc tgttagtgac tttaaaaagt aaagctactg
    14881 taaatattcc taaaattata ggaatgatta tcatcaataa tcctataata aaatatttaa
    14941 tttctttctc ttttctaaat ttctttatga actctattgc ttgtaaataa atcgctatta
    15001 aaaataatgt tgaaaaagtg ttatttataa ttatagctcc ttctggatgt gaaaatacat
    15061 tattaattat ttgatttcct atagccataa taacagacca aatatacaat ctacttatat
    15121 atttttttct gttactagtg tgataaaatc cttcaacagc catgaatata aacagtggtg
    15181 ctgatattct gcctacccaa tgaaaccaaa ttggtatttg cattgtttgt ggcataaatg
    15241 ctgctatatg gtcaaatgtc ataaatatta atgctaaaat cttaatagta aacccactta
    15301 tacctttttt aaaaaaatcc atatcatatc tcctaatttt gttttatctc tataataatt
    15361 tttgttccta ttccaatttc actacttaca taaattttac ctttatgaat ctctattatt
    15421 tctttagaaa tagccatacc aagacctgaa cctttatgca tctcacctgt attagtacct
    15481 ctataatatt ttttaaaaat atgtttcaaa tcacttttgc ttattccaat tccatcatct
    15541 tttattataa tttctatatt atcttttttt acaatttcta cacttatcaa agttccttcg
    15601 ctattatgaa ctattgaatt aaatataaga ttggttatag cccttctgaa taagattgaa
    15661 tctacatata cttcaattaa atcttcatta ctttcaaatt caatattcct atttttatat
    15721 ctattatcat ttaaaatatc aattattata tctctgacta aactgactaa atttattttt
    15781 ttcttgtcca gaactatagt attatttttt aatcgagtag ataaatttaa atcatcaact
    15841 aaatctttta tatacttaga cttattatat ataatttctg tatactcttg tatttcatct
    15901 tcttcaaact cataatcttt gtcattaatt atctctgcat acccttgtat agatgctaga
    15961 ggtgtcttta tatcatgtgt tatatttgcc aaccattcct ctctcaactc ttcattttct
    16021 tttctctcaa cttcatttac tcttaaagta tcagctaaca tatttatatt tttaaaaact
    16081 tcttcatata tacctctgtc cttaagatat aaactataat ttccattagc catagtctca
    16141 atactccata gtacgcttga aattggtttt gtaagttttc tactaaataa atatcctaca
    16201 cctaaagcta ccacgctatc aattactagt gttataatga taactttatt taaagttttt
    16261 ttaatgttat tttgagaata ggttaaaatt attcttgata tatctctact aggtatacct
    16321 actattatgt ttagatgttt tttgtttaaa tatttttcta atacaaaatt aacatacttt
    16381 gtttctatat acttgtaatt attcaccatt tgaaagggtg tatatttttt gggagtatcc
    16441 tttggcacat ttactccata aacttcctct cctaaatcat ttaaaacctg tatccaggaa
    16501 tttgattttt ctaatttttc agctccaatc ttagatagtt taaattctcc atctttttca
    16561 tataaatctt tttcaaaaga acgtgcaaat tcttcaggat tatttccaga atctacaact
    16621 ttaaaaaaac tattagttga aatcacatac aatatagata tgatatttat aattactact
    16681 gatatagcta caaacacaat tgtaaatata aaatttctag taatcttcca cttcatattc
    16741 taatcttcct ttactgctaa tttatatcca agacctttta ttgtcagaat atattcaggc
    16801 tttgaaggat tatcctctaa tttttcccta atttttctta tatgaaccat tatagtattg
    16861 tcaaatccaa cataatcttc tccccacact ttatcccata gtttttcttt acttataatt
    16921 tgattttgat tatgtgcaaa taaagatagg atttttagtt cctttgcaga cagtcctata
    16981 gattttccat cttttataag ttctgcccta ctttcattta atatatatgg gccaaatgat
    17041 ataatttttt cttcattatt atttagattt ttactttcgt tttgagcatc actaaaataa
    17101 cttaatcttc tcaaatgcgc tttaactcta aaagccactt ccttagggct aaaaggtttt
    17161 gtaacataat catctcctcc aatcgctagt ccaagtaact tatctaattc ttcggtttta
    17221 gctgataaaa atattattgg agaattggag gtttttctta tttctttaca aatatcataa
    17281 ccttcgccat ctggtaacat aatatccaat acaatcaaat caggattaat acttttaaat
    17341 aattctaatc cttctttttt agtttttgca gtatatatat tattaaggcc ctcttttttt
    17401 aggacagttt ctaaaagctt caatatttct acttcatcat ctattattaa aacacgattt
    17461 tccataaaca acctcctgta ataatttaca tatatattag catatatttt atctaaaatt
    17521 catttatctt atttttaatt aaactaaaat ataaataaaa ttactattat ttttagttaa
    17581 aaccttttgc ttgatgtaaa attttcatat gttattttag ttaacactat cattaatata
    17641 attgagatta ctatagaaaa aactatcaaa atacttggta cattatactt aaccatttgt
    17701 tggctcatca taatccaatt tggagtcact gacataaatt ttatagcttt atctggtata
    17761 aaacctacac taaagtatgg aattgccatt atcaatccac ctagtataaa tggaattaca
    17821 gccgatttaa atatagatga aagtgttaag cctatttgtg caaatataaa agaagcaaaa
    17881 atagtagtca atataacaat tatatacatt tgtattactg taagatttaa attactattt
    17941 ccaaagtacc ataagttatg aatcgattca tttaaatttt taaaatcaaa aaaactaaaa
    18001 cctctaattc ctactaacaa tataaaagaa atattaataa tagataaaat taatccatta
    18061 gctactagtt ttgataatac tactgatttt tttccctttt tagttgtatt tattaaacct
    18121 gtcatattag aatcatattc tttaatgtaa tttccagaag ttattataaa cattatcaaa
    18181 cctattagag gtattgagcc ttctatcttg taaaatatat ctgcataagt atctaaaaca
    18241 tcaaactttc taatcagaaa aaatccaaaa aatattaaaa acagccaaat tatccaaaca
    18301 ctctttgatt ttaatatttt tatcatttca gctttaacta aatacatcat ttctactaca
    18361 cctcccttgc atcttctaaa tcaaaataaa acatgtatac atcttcgaat tttgcttgaa
    18421 ctggttgtat attatcctcg cttggaatat cctctgaaac aattctaagt actactgaat
    18481 caatatcact ttgaatactt acaaccttat atttagattg tatatcatca acttcacatt
    18541 catttttaac ttgaacatta tatactttat tttccatgtg acttaatatg tctttgtgtg
    18601 ttcctttcat taggagtttg ccatctttaa tcattattgt ttcctttgca actgattcta
    18661 tatcggaaat tatatgagta gaaagtatta ttatcttatc tctagacatt tttgctatta
    18721 aattcctaaa tctagctctt tcttgtgggt caagtcctgc tgttggctca tcaaggacta
    18781 ttatcttagg gtcgtttagt aaaacttgtg ctatcccaac tctcctcttc atacctcctg
    18841 aaaattttcc tatagactta tttctcacat cataaagacc tactaaatct aataattctc
    18901 ctatcttact atttaaatat tttcccctta aaccttttaa agctccaata tactgtaaaa
    18961 attcttttgc tgtaaaattt ttataaactc caaattcttg tggcaaatat cctaaaatat
    19021 ttctataatc agcatccatt ttaaatatat cctcaccatt ataaagtatc tgaccttcat
    19081 caggttttat caacgttgtt atttgtttca ttaatgtaga ttttcctgct ccatttggtc
    19141 ctagaagacc ataaactcca ttttccagag ttactgtaat cttgtcgttt gctacttttt
    19201 taccatatat ctttgaaaga ttttctattt ctaatttatt catcttaact ccccttttat
    19261 ctacttatat aatctgattt tattactaaa aaacataatg acatagcacc tatcaatatt
    19321 gccatcaaaa gtcctattgc tatattgaca atgtctatat tcactttaaa tatcataata
    19381 tcacctagat aatttcctat tattttatta aaaccaaata tcaaatcata ataatttaca
    19441 tttgatacaa ctgaaagtaa ttttttaggt aatatatgga ttaccgacat tatcttagtt
    19501 atagatataa taaatataaa aaaacttatt gaagatattg aagacttact tataaaagac
    19561 ccaaatatgg ctatcatggc ccatccttca aacatcaaaa gctctatgcc tatatttaat
    19621 attacatact ttgttatact taaattagtt ttcaatgcaa ctacattgtc tactattcta
    19681 aaagattcta agtctccatt aacaggtact ccttgttgca tacaagttat aataaatatt
    19741 cccattaaat aaacagaata aattactaat ggaactaata aagcaacaaa tattttagac
    19801 tttaatgctt ttttcttctc ttttgatgat agtatgatat cttttaccga agtaacgact
    19861 tcatctacat aaatattgga tataattata gatataatga ttaacattcc tacatttata
    19921 agtgaatttg tgactctata gttaaatact ttccaaaaac taatatcctt atattcattc
    19981 acacttagat tatcaagttt tttctttgac attaattcaa tttttttaga aaattcacct
    20041 gtatctgttt gatttgaaaa ctgctttaaa acattaatct tattttgaaa tttctcatta
    20101 cctacgtcga taccacttct cgtatcttct atacgtcctt tttctttatc tatataataa
    20161 ctttctgttt ctaaaacagg cgtaataaag atactaatca ttagtattaa cactaatatc
    20221 cctagagata taaacatact cttagattta gccaattttt ttatttccca atttaccaat
    20281 atatttctcc tcctaaatca ttttaattac acatatatat taaaacttaa atcttatata
    20341 aatataatac taaccttaaa taaagcttaa attattttat aatttatagg tgtgtttatt
    20401 attggagtta catttattat ttttctggga aattatacat tttcaattat ttttattatt
    20461 tttgatattt ttattgattg gaaattttat tgttgttcaa attgtagtta ttctttaaat
    20521 ttaaagatgg agttttttaa gaatagaacc tactgtcctt attatggaaa gattattaaa
    20581 tagttgcata taactttatt tatcttgaat cttattttta aaaacaatta taattttaga
    20641 atattttcta ttctcaaaca agcatgttga ataatggagc atcttctagt attatatact
    20701 tgtagaataa aactaaattg gtaaaactgg gaatatttaa ccttaaggag ttaagttata
    20761 gaaactagta ctaaaaaatt ttataaatta tgttaattga ctaatagaat gcgacttttt
    20821 atttttacta aattttttag ggggatggat aatatgttta ttggagaaat agacaaatgt
    20881 acacatatac taactgctta catcagtagt tcatatgatt attgtaattt tttagataca
    20941 cagttagatg attttatatc agaatatgga gaaacggtag ttgaaacctg cttacatcaa
    21001 gtcttattat tagtaagtag atacaattaa aactaaattt ttctagaaaa acctttttag
    21061 atttatctac tctaataaat atataatttt ttgtacttta taagtaacta taacttctgc
    21121 taaagtaaag atgtattggg agtacatctt tactttccca ttatagaagt taaaagcata
    21181 caccataaaa ttaatcatcc aatacaaatt atatatttcc tatgtctaac ttaatttaca
    21241 agaatcattc tatatgcata ttctgcaatc cactaaacat ggctctaaac ctttactatt
    21301 ttatacattc tctataaatc atacaaatca tatataaaat ccccctaata tgtttaaacc
    21361 acctataaaa taacaccaat atttagaata ttcaatatca actgcataac tggtcaataa
    21421 aaacgtataa ctagacaaat ttcaatattt atataaataa tacaagaaaa acaagcattt
    21481 tatttatata agttttttat tttttgttta tattaaaaaa ctatattgat taatttattt
    21541 tatttagtaa ttataaaaat tcgtcttaga atatattcta tatttgtaga ttaactttaa
    21601 tatttttaat ttcacaaaaa ttaaactccc aatattttta tccactttta tctcattaat
    21661 taattatatt atttttatgc tttttacaa
//
LOCUS       DAYAOO010000070        21362 bp    DNA     linear   BCT 12-OCT-2024
DEFINITION  TPA_asm: Clostridioides difficile isolate ST8-SSI-h139-18
            SAMN40601845-rid21577343.denovo.070, whole genome shotgun sequence.
ACCESSION   DAYAOO010000070 DAYAOO010000000
VERSION     DAYAOO010000070.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN40601845
            Sequence Read Archive: SRR28438827
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 21362)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 21362)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-MAY-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-MAY-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002157583.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002157583.1
            Genome Coverage       :: 163x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/11/2024 16:19:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 4,038
            CDSs (total)                      :: 3,963
            Genes (coding)                    :: 3,930
            CDSs (with protein)               :: 3,930
            Genes (RNA)                       :: 75
            rRNAs                             :: 6, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 60
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 33
            CDSs (without protein)            :: 33
            Pseudo Genes (ambiguous residues) :: 0 of 33
            Pseudo Genes (frameshifted)       :: 7 of 33
            Pseudo Genes (incomplete)         :: 25 of 33
            Pseudo Genes (internal stop)      :: 11 of 33
            Pseudo Genes (multiple problems)  :: 8 of 33
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..21362
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN40601845-rid21577343.denovo.070"
                     /isolate="ST8-SSI-h139-18"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Denmark"
                     /collection_date="2018"
                     /collected_by="Statens Serum Institute"
     gene            167..1177
                     /locus_tag="ACGI5H_002810"
     CDS             167..1177
                     /locus_tag="ACGI5H_002810"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018112772.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4116 domain-containing protein"
                     /protein_id="HFG9698507.1"
                     /translation="MHEDKNDIFESIDTEDFDNKTEEECLELVRKNGLNLIYIKNQTE
                     EICLEAVRQNCNAIKCVQNQTEKICIEAVKQDWRMLEFVEEPTEEICMLAINQDGTAL
                     KYIENQTEELCLRAVEKNGAALEYVKEQTEEICIEAVRNSEFGLARVKNQTEKICMEA
                     VKHCSYNLKWVENQTEEICMEAVRQNGLDLKFVKNQTETICLRAVRQNGMALEFVKEQ
                     TVGICLKAVRQYGMALKFVKEQTEEICTEAIKQDKRALSFVKGDKEKYKALYDNNEPF
                     AKRYVRNVIEKENRALIKKGEENAKIKIAGKLYDRGMSFEDISDIVEIEISKLKVSLG
                     VF"
     gene            1313..1801
                     /locus_tag="ACGI5H_002811"
     CDS             1313..1801
                     /locus_tag="ACGI5H_002811"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888613.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0010181 - FMN binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="flavodoxin domain-containing protein"
                     /protein_id="HFG9698508.1"
                     /translation="MKITVLYQTRSGNTERVAKLIEEGAKKVDGVDVKLMRLDNIDLD
                     YLNESKAVIFGTPTYLANTTWEVKKWFDEDSKKVNLAGKLGAVFATCDYICGGPDVAI
                     LTIVGHLMVKGMLVYSGGGSLGKPFIHLGHVHSIEGPELQDEKAIIFGERIATKAKEL
                     FA"
     gene            1977..3905
                     /locus_tag="ACGI5H_002812"
     CDS             1977..3905
                     /locus_tag="ACGI5H_002812"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437567.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EAL domain-containing protein"
                     /protein_id="HFG9698509.1"
                     /translation="MVWHIEYEIFSAIIVIFLMVYFFRSKFIPTLQNKIYCALLIFSF
                     LFIISNILGSFCLNNIDKIPIFITFLLNQIYLLLLPIPAALVSFYVMAIIYQDIRYMK
                     KRLLFLSIPLIICIILSITNPFTHILFGLSKETGYIRGCGYVATFASFFFYAIYSAFL
                     SFKYRKAMHESKIWAIRGFLIVSIVAIILQAIFLQYLLTGTACACSLLLTYLSMQNRG
                     LIIDDLTGVLNRQSFIQELDLNINTEQSGFIITIALDDFKFMNETFGTKNGDIALKEV
                     GKYLIQIHDVNHVYRIGGDIFSIVVNSQLGIEPDDIIRKIEERFKKPWLVEEISFNLA
                     TSIAVVYYPENAETTEDVIVAIDFSIHEAKRSESRRVVYADASISEKIKKKHVIKNCL
                     KEALKNDGFEVYYQPIFSNSRGRFTSAEALLRLEHKELGFIPPDEFIPIAEQTGLINS
                     IGLVVFEKVCRFIASDEFEDLKLDNIAVNLSVVQCMQKNLADDLLYLMNKYNVSPTKF
                     KLEITETVAMGSFNIIKETMERLIDLGVKFALDDFGIAYSGVTNMLSLPFSVIKLDKS
                     LIWSMNEDSRHKLTVETIIALINKLNMKAVAEGVETIKCAEDLIAMECEYLQGYYFSK
                     PVPEDVFKNLLKENTFTS"
     gene            4082..4492
                     /locus_tag="ACGI5H_002813"
     CDS             4082..4492
                     /locus_tag="ACGI5H_002813"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418487.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="universal stress protein"
                     /protein_id="HFG9698510.1"
                     /translation="MNKKKILVPIDGTERSMHSLEFIKGIFKKDEVEVEIMNVKELVF
                     IDGISLAEEIKNSENLGRRILDKAAEIMGEYDVKVHFTFGYPGDEIIRKAKEDNVDFI
                     VMTKSTKKGLTRMIGSVTASVVKQAKCIVMIVPE"
     gene            4514..4816
                     /locus_tag="ACGI5H_002814"
     CDS             4514..4816
                     /locus_tag="ACGI5H_002814"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418488.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIBC"
                     /protein_id="HFG9698511.1"
                     /translation="MNKKIVAVCESERSLNSLKTAANDLGFDLVYEIQENDNIKNELS
                     IYDIEDASIVLFVTSDSIESIEKIDRFIDREFYEVDPKYIIEDAKSIVSEILIDLN"
     gene            complement(5033..5725)
                     /locus_tag="ACGI5H_002815"
     CDS             complement(5033..5725)
                     /locus_tag="ACGI5H_002815"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888618.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FCD domain-containing protein"
                     /protein_id="HFG9698512.1"
                     /translation="MKSLNATEKIIDYIKLNILNGTFKINSKLPSERKIADLFNISRI
                     PVRNAINILCKEGILRAVPYSSPIVEGFKKVDLFDDGEIYKNHNIQEFYVESLRARQL
                     IESEATKLAILNATSKELQKIKYTYLKSIEELDKVSHGLIEECYDADLQFHKEIILAS
                     HNPIFIKYYELIPKTVSSNQYFGFKYRNSLKDMISHHNKIMIAFDSKDSYLGYTSMYN
                     HLEDVIQLFQHD"
     gene            complement(5751..6938)
                     /locus_tag="ACGI5H_002816"
     CDS             complement(5751..6938)
                     /locus_tag="ACGI5H_002816"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905132.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HFG9698513.1"
                     /translation="MKKISNQKLLLLSIVTFFWFSQYVYIPFQNPYLSACNVSTNMIG
                     IIIGAYGISQCLLRLPVGVFADSINKHKIFILSGIFFAGLASLIRVFSPGGNGFLIAN
                     ILSGISSSTWISYMVHYTNFFSTEHQQKATSTIILVNNLGMLIGFVMSTLFYEKLGMT
                     ALCIMSVLSSVIGTILALNIKNHNSKKIPEKISIKKYLSICKDKRLVFFSFMALIQQG
                     IQMSTTMSFTTQILKNLGSSSTLIGLSSIFYMVCAVASSGFASTKFCTKYGPKFWIPL
                     VFILVSAYCFLVPTIKNINIIFVLQVLPGISTGILLSYLTSESMKNVPKHQKSTAMGF
                     FQAIYAIGMSVFPMIVGKISEYTSIQYGYFILAIIAILASILSYTYYKKVDLTLNYDI
                     IQS"
     gene            7274..9151
                     /locus_tag="ACGI5H_002817"
     CDS             7274..9151
                     /locus_tag="ACGI5H_002817"
                     /EC_number="2.7.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895840.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_function: GO:0015573 - beta-glucoside transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA];
                     GO_process: GO:0015759 - beta-glucoside transport
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="beta-glucoside-specific PTS transporter subunit
                     IIABC"
                     /protein_id="HFG9698514.1"
                     /translation="MDYKNIAQEILLNVGGKENVNEVTHCMTRLRFKVKSASKVNKDK
                     LSKTEGVITVVESMGQIQVVIGNKVKKVYDEVIKIVPQSNNIGKKNESQEKQGIINSI
                     LSAVAGIFTPTIPAIAGVGMIKGILSVLAMYYMNKNGVDIKETQSYIILNAMADSIFY
                     FMPIILGYTAAKVFNANKIISMVLGATLCYPTFTALMAGEESVRFLGLAVTKATYTSS
                     VIPIIIAIWALSYVEKVLEKYIPEVIKIIMVPTLSLVVMLPATLFLFGPIGIYIGNVI
                     NFSYKYIYELSPALCGAFVGGLWCVLVIFGAHRALLPIGISDVAQTGRQNLLAFAGAA
                     NFSQAGAALGVFFKTKNQGLKTISMSATITALFGITEPAIYGANLRLKKPMVCAVICG
                     AFGGAIMGMGGAYGNAFANQGVLTIPVYAEAGALGFLSYLGGCAIAFFGSAISTYLVG
                     FEDLEESSNKENSSIKVETKDGVIDITSPVEGECIELSEVKDDVFASKAMGEGIAVLP
                     TKGVITAPTDCEVASLFPTLHAIGLKLDNGAEMLIHVGINTVELNGKYFTKHVNQGDL
                     VKKGDKLISFDIDKIKKAGYDVTTPVIVNNTFDFGQVVSCKSSYVSTNDNIISLVLAG
                     N"
     gene            9508..10914
                     /locus_tag="ACGI5H_002818"
     CDS             9508..10914
                     /locus_tag="ACGI5H_002818"
                     /EC_number="3.2.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860965.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016798 - hydrolase activity, acting on
                     glycosyl bonds [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
                     /protein_id="HFG9698515.1"
                     /translation="MNTGFPKDFLWGASSSAFQVEGAWDKDNKGKTVADYNSFKKSHL
                     QADTKVASDFYHNYEEDIELMKELGMKTYRFSISWARIIPDGEGEINQKGLEFYNKII
                     DKLIECDIEPFVTLYHFDLPFKLVEKYNGWESRETVYAFERFAKICFKHFGDRVKYWQ
                     PHNEQNLIVRVEERINIYDETDSWKIDKMRAQMDYNLCLAHALAVNACHEMIKESKIG
                     AAVSSSVTYPLTSKPEDVYAARMNDNFKVYYMLDMHHYGEYPGYYMKYLEKRNIVPHM
                     EDGDKEILKKAKMDFIAVNYYRTNCAEALPEDSQHPFGLREGTVDFSMYGLFKMSMNP
                     NLEASEYGAAIDPSGLRVALNEYWQRYHLPVIITENGLGAKDILEDGKIHDDYRIDYL
                     RSHINACKLAIEDGVEMIGYCPWSFTDLLSSSQGFNKRYGLVYINRTDHEVLDLKRIK
                     KDSFYWYKEVIENNGIVK"
     gene            10942..11790
                     /locus_tag="ACGI5H_002819"
     CDS             10942..11790
                     /locus_tag="ACGI5H_002819"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454252.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HFG9698516.1"
                     /translation="MYITKVLNNSLLLAKDDNDEEIILMGKGIGHNYKAGSELNKKDI
                     EKIFVLHDENIKKSIIQLATEIDAEYFGIAQMIIAYGIEKYNLKLMNHIYLALTDHIA
                     FAVRRFKEGIMIENHYLFEIKEFNPKEYDIGKYAITVFKEVLGLDLPEEEIGNIAGHF
                     INAQQDNPYSDRNKRSAKIVNAILQIVHYHFSIVYNKESFYYRRFVMHLKAFSQRFLA
                     NEPSREKIDFIYEQVQKNCKEEYECVKKVGAYMYKEYSRELPRQEELYLMIHIHKILG
                     ELCENS"
     gene            12451..13143
                     /locus_tag="ACGI5H_002820"
     CDS             12451..13143
                     /locus_tag="ACGI5H_002820"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728879.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000156 - phosphorelay response regulator
                     activity [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HFG9698517.1"
                     /translation="MNKVLIIDDDKDLCILLKKSISIEQIEANYCHSGRDGLVELSKQ
                     DYQLVVLDVMMPGMDGFETMEQIRKYSSIPILMLTSKSDNYSKVHGLRAGADDYLTKP
                     FEITEFTARVLSLIRRYTRFNPKNEEPQQLSFKGLLIDLDQHTVTTNGEPMLLPPKEF
                     GVLLYCARHQGKILTKQQIYEAVWGEPYVYDDSNIMAIISRLRKKIELDPSSPIYLQT
                     IKGIGYQFNTEV"
     gene            13140..14075
                     /locus_tag="ACGI5H_002821"
     CDS             13140..14075
                     /locus_tag="ACGI5H_002821"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418502.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing sensor histidine kinase"
                     /protein_id="HFG9698518.1"
                     /translation="MKMDEQTIILFLLLLSIGLLFLSIFAFSKLGHIYKRLKDIEEIL
                     ADVQIGDENRKILIKPCDVMAPLVYQLNEIVYDYENKLLSLKKSDKASKQLMTSLSHD
                     VRTPLTTLIGYLDAVHSGIVIEQEREEYLEIARRRAYDLKDYIDVLFDWFRLNSDEFT
                     LSIESVEIAELSRNILKDWIPIFHEKKLNFEIDIPENRLMVNLDPDGYSRVVNNLVQN
                     VLAHSKARQIKITMSEDSRMVLLRVEDDGVGIARENLPHIFERLYKCDKGRSEKGSGL
                     GLSIVSQMVERMGGQVSVESEIGKYTVFTVSLPLI"
     gene            14223..15146
                     /locus_tag="ACGI5H_002822"
     CDS             14223..15146
                     /locus_tag="ACGI5H_002822"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019639192.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HFG9698519.1"
                     /translation="MNNLIIETKNLTKQYGAQKSVSNLNIHVQKGRIYGLLGRNGAGK
                     TTTMKMLLGLTKPTTGEIKIFGQDIHNNEKKLLPRIGCLIESPGFYPNLTGTENLKIF
                     ARLRGIPKKNAVESALDVVGLPNNDKKLFSQYSLGMKQRLAIALAIMHDPQLLILDEP
                     INGLDPIGIAEVRTFIRDLCTERGKTILISSHILSEIALLADDIGIIDHGILLEEESL
                     AQLEEKNSKYIHFAVSDAAQAARLLETQLNLKNFKVADNYNIMLYDTDVSVAEINRAF
                     ILNNIEVSESHLCEDTLEDYFKKVTGGEGIA"
     gene            15130..15900
                     /locus_tag="ACGI5H_002823"
     CDS             15130..15900
                     /locus_tag="ACGI5H_002823"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012816056.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HFG9698520.1"
                     /translation="MKELLDIISCEFSKLKRLKFILISILGACLFPIPATILIAKDNL
                     PFEQLFKLVVNFGYFLLLPIVLSIVASQLFFIERDNDVLKNLATVPVQKGKLALAKLA
                     VLLFISLFYSVAGLGATIIGGFIVGIVEGVAVKLGMSIAFGIMFFVTVLPVVVLIVYF
                     NRSYIFSIILSFVYAIFNFSISLNIINFEPNNPILSVLPAPVIMRWWMAFWGDPTGEY
                     TALRQPYLLSTPACVGILCLITIIAVLLICMIYKKQEN"
     gene            15910..16692
                     /locus_tag="ACGI5H_002824"
     CDS             15910..16692
                     /locus_tag="ACGI5H_002824"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418511.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HFG9698521.1"
                     /translation="MLDIITTEFQKIKRYNILWIGVVAVLFSALLAVFQVVSSHGSDP
                     LTYESFANGVIWNNFSLSFPFGITLIGGYLINREYTDQTLKNILTVPISLRKLLVGKL
                     IAVGGITVLLSLFSFLCTFILGLLFCNINISVTLVVKSLVQILSVNLYCYVAVLPIIA
                     YFGRKQNAFLTGVGIAFVYGFCGVFVAGRNLTDFYPITAGLGLVGYNNGAGTVYQPLI
                     GAMTLIVILILTTILLVFTPNYDKVMTISKKKGIKHKKYSHK"
     gene            17069..17605
                     /gene="rbr"
                     /locus_tag="ACGI5H_002825"
     CDS             17069..17605
                     /gene="rbr"
                     /locus_tag="ACGI5H_002825"
                     /EC_number="1.11.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418513.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0009055 - electron transfer activity
                     [Evidence IEA];
                     GO_function: GO:0016692 - NADH peroxidase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="rubrerythrin"
                     /protein_id="HFG9698522.1"
                     /translation="MNLKGTKTEKNLMAGFAGESEARNKYTYYASKARKEGYNQIAAI
                     FEETANNEKEHAKLWFKLLHDGMPSTEENLKDAAAGENYEWTDMYAKFAKEAREEGFD
                     KIAYLFEAVGKIEKEHEERYLKLLENLNEGKIFKRDEEVVWQCQNCGHVYVGTEAPEK
                     CPVCDHPKAYFNIKAENY"
     gene            17637..18026
                     /locus_tag="ACGI5H_002826"
     CDS             17637..18026
                     /locus_tag="ACGI5H_002826"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905140.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional repressor"
                     /protein_id="HFG9698523.1"
                     /translation="MKFSKQRELILNEILNNPVHPTADYLYENLKKDNPNLSLGTVYR
                     NLAQLTEHGFIRKVSIPGYPDRFDGRIDNHYHIICEVCGEVYDLESEVLNNLQELISE
                     ETDIKITSYNISFKGICNNCKRCSQVG"
     gene            18063..18449
                     /locus_tag="ACGI5H_002827"
     CDS             18063..18449
                     /locus_tag="ACGI5H_002827"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004453642.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005506 - iron ion binding [Evidence IEA];
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="desulfoferrodoxin family protein"
                     /protein_id="HFG9698524.1"
                     /translation="MCSEQKFFICETCGNLVGMIQSGGVPIFCCGKPMKELVPNTTDA
                     AVEKHVPVIEVDGNNVTVKVSSTTHPMTKEHHIAWVYLMTEQGGQRKCLAVDGEPVVK
                     FALNDDDKVISAYAYCNLHGLWKAEL"
     gene            18576..20018
                     /locus_tag="ACGI5H_002828"
     CDS             18576..20018
                     /locus_tag="ACGI5H_002828"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418516.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0015930 - glutamate synthase activity
                     [Evidence IEA];
                     GO_function: GO:0016638 - oxidoreductase activity, acting
                     on the CH-NH2 group of donors [Evidence IEA];
                     GO_process: GO:0006537 - glutamate biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate synthase-related protein"
                     /protein_id="HFG9698525.1"
                     /translation="MSIYKCSVCGYIYDESKNDKTWDELSEDWECPVCTKGRSYFGKI
                     STVYYEEDEKIAEDIVEDESKLNTEKEGDLNYLSTYLRRDDEVEKHMDIIHEMAVTGK
                     SIIEPMRTKLPVISWDDILIMGAQLNPLPLNEHDEVNTTTIIGKKAKKPMIIENPVYI
                     SHMSFGALSKELKIALAKGAAQNKTAMCSGEGGILPEEKEASYKYIFEYVPNKYSVTE
                     ENLKNSDAIEIKIGQGTKPGMGGHLPGEKVTEEIAKVRNKPVGQDVISPSCFEEIQSK
                     EDLKKLVDELREVSEGRPIGVKISAGHIEKDMEFIAYAKPDFVTIDGRGGATGASPKL
                     LKDATSIPTIFALYRARKYIDTHGLDIDLVITGGLRISTDFAKAIAMGADAVAIASSA
                     LMAAACQQYRICGSGKCPVGVATQDEELRKRLHIENSANRVANFLNVSLEELKTFARI
                     SGHKDIHDLSVDDLYTVNSEISNYTNIQHV"
     gene            20315..21130
                     /locus_tag="ACGI5H_002829"
     CDS             20315..21130
                     /locus_tag="ACGI5H_002829"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728724.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HFG9698526.1"
                     /translation="MERLKIQVLVDNNTYIDRYFVGEPAVSYYIEIDGNRILFDSGYS
                     DVFISNAEKLNIDLGNLTHVVFSHGHNDHTRGIQFLENRYDLSTVELISHPNCFIPRK
                     HGEKSIGAPFSAEEIKNIFMYNPKDKPFNLSKNCVFLGEIPSINDFEKRAKIGKCKIG
                     DLWEDDYVLDDSAIVCKTDKGIFIVTGCSHSGICNIVEYAKKVCGDDRVIGILGGFHL
                     FELNNRLDSTIQYLDKEEMRMLYPCHCVSFKVKAKMNEILNINEVGVGLTISI"
BASE COUNT         7890 a         2483 c         3913 g         7076 t
ORIGIN      
        1 attttgggta ttgtatactg gaattagagt aattaattta ttttttaaca tacaaatgat
       61 tttatgaaaa aaaacaagac tcaaaaattt ttatattctt tgatagaata aaattgagag
      121 taaatttatt gaattttata aaatttataa ggggtgagtc taagatatgc atgaagataa
      181 aaatgatata tttgaatcaa tagatactga ggattttgat aataaaacag aagaagaatg
      241 tttagagcta gtaagaaaaa atggattgaa tttaatatac ataaaaaatc aaacagaaga
      301 gatatgtcta gaggctgtta gacaaaattg taatgcaata aaatgtgttc agaatcagac
      361 agaaaaaata tgtatagaag cagttaaaca agattggaga atgttagaat ttgtggaaga
      421 gccaacagaa gaaatttgca tgttggctat taaccaagat ggaacagcat taaaatatat
      481 agaaaatcag acagaggagt tatgcttaag agccgttgaa aaaaatggtg cagctttgga
      541 gtatgtaaaa gaacaaacag aagaaatatg tatagaagca gttagaaaca gcgaatttgg
      601 attggcaaga gtgaaaaatc aaacagaaaa aatatgtatg gaagcagtta agcattgtag
      661 ctataatcta aaatgggtag aaaatcaaac agaagaaata tgtatggaag cagtgagaca
      721 aaatgggctt gatttgaaat ttgtaaaaaa tcaaacagaa acaatctgtt taagagcagt
      781 aagacaaaat ggaatggcat tagaatttgt aaaggaacag actgttggta tatgcttaaa
      841 ggcagtaaga caatatggaa tggcattaaa atttgtaaag gaacaaacag aagaaatttg
      901 tacagaagct ataaaacaag ataaaagagc acttagtttt gtaaaaggag ataaggaaaa
      961 atataaggct ctatatgata ataatgaacc atttgcaaag agatatgtta gaaatgtaat
     1021 agaaaaagaa aacagagcat tgattaaaaa aggagaagaa aatgcaaaaa tcaaaattgc
     1081 aggaaaactt tatgatagag gcatgtcttt tgaagatata tcagatatag ttgagattga
     1141 aataagcaag ttaaaagtga gtttaggtgt tttttaaagt aataaatgta ggtgtttttt
     1201 atgggaaata gttaataaaa aaataatcga ctagctcttt gtaggacagc aaaattagtg
     1261 atataatttg atgtataata aattattttt attagataag ggggaattaa agttgaagat
     1321 tacagtatta taccaaacaa gaagtggaaa cacagaaagg gtcgctaagc tgatagaaga
     1381 gggcgctaaa aaggtggatg gagtagatgt aaagcttatg agacttgata atattgattt
     1441 agattattta aatgaaagta aagcagtaat atttggaaca cctacttatt tagcaaatac
     1501 aacttgggaa gtaaaaaaat ggtttgatga agattcaaaa aaagttaatt tagctggaaa
     1561 attaggagct gtttttgcta catgtgatta tatatgtgga ggtccagatg ttgcgatact
     1621 tactatagta ggacatttga tggttaaagg gatgcttgtg tattctggag gtggttcttt
     1681 aggaaagcca tttatacatt taggacatgt acattcaatt gaaggtccag agttacaaga
     1741 tgagaaggct ataatatttg gtgaaagaat tgctactaag gcaaaagaac tatttgctta
     1801 atttctatat gcatagtaat gattagagta aatttagggt tttaatggag atttgaagta
     1861 aaagttataa aataaaaaat tttccataaa attactcaag atgaattata atataattat
     1921 aaataaatta tattattaaa atatttaaaa tcaaacgtca atagcgaggg aagtttatgg
     1981 tatggcatat agaatatgag attttttctg caattatagt tattttttta atggtatact
     2041 tttttagaag taaatttata cctactttac aaaacaaaat atattgtgca cttttaatat
     2101 tctcattttt atttataatt tcaaatattt taggttcatt ttgtctaaat aatatagaca
     2161 aaattccaat ttttattact tttttattga atcagatata cttattgtta ttgccaatac
     2221 cagcagcact tgtatcattt tatgttatgg ctattattta tcaagatata aggtatatga
     2281 aaaaaagatt attattttta tctataccac ttataatttg tataatctta tctattacaa
     2341 atccttttac gcatattcta tttggattgt caaaagaaac aggttatata cgaggttgtg
     2401 gatatgttgc aacttttgca tcttttttct tttatgcaat atattcagca tttttatctt
     2461 ttaaatatag aaaagcaatg catgaatcaa aaatatgggc tattagaggt tttcttatag
     2521 tttcaattgt ggcaattatc ttacaggcaa tttttttaca gtatcttctt acaggaactg
     2581 catgtgcatg tagtttactt ttgacatatc tttctatgca gaatcgaggt cttattattg
     2641 atgaccttac tggtgtactc aatagacaat cttttattca agagctagat ttgaatatca
     2701 atactgaaca atcaggattt attattacaa ttgcgcttga tgattttaag tttatgaatg
     2761 aaacttttgg aacaaaaaat ggagatattg cactaaaaga agttggaaaa tatttgattc
     2821 agatacatga tgtaaaccat gtatatagaa tagggggaga tatattttct attgttgtca
     2881 atagtcaatt aggtatagaa ccagatgata ttatcagaaa gatagaagaa agatttaaaa
     2941 agccttggct agtagaagag ataagtttta atttagcaac tagtattgct gttgtttatt
     3001 acccagaaaa tgcagaaacg acagaagatg taattgttgc tatagatttc tctatacatg
     3061 aagcaaaacg ctctgagtca aggcgagttg tttatgcaga tgcgtctata agtgaaaaga
     3121 taaagaagaa acatgttatt aaaaattgtt taaaagaagc attaaaaaat gatgggtttg
     3181 aagtgtacta ccaacctata ttttctaata gcaggggcag gtttacttca gcagaggcat
     3241 tacttaggct agaacacaaa gagttaggtt ttatacctcc tgatgaattt attccaattg
     3301 cagaacaaac aggattgatt aactcaattg gattagtagt ctttgagaag gtatgtagat
     3361 ttatagctag tgatgagttt gaagatttaa aattggataa tatagctgtg aatctttctg
     3421 tagtacaatg tatgcaaaaa aacttagctg atgatttact ttatcttatg aataaatata
     3481 atgtatcacc aactaaattt aaacttgaaa ttactgagac tgtggctatg ggctctttta
     3541 atataattaa agaaacaatg gaaagattaa ttgatttagg tgttaagttt gcacttgatg
     3601 attttggaat tgcttattct ggagttacta atatgctttc tttaccattt tcagtaatta
     3661 agttagataa gagtttgatt tggtctatga atgaagatag taggcataaa cttacagttg
     3721 agacgattat agcacttata aataaattga atatgaaggc tgtagcagaa ggtgttgaaa
     3781 ccattaagtg tgctgaagat ttaatagcta tggagtgtga atatttgcaa gggtattatt
     3841 tttctaaacc agttccagaa gatgttttta aaaatttgtt gaaagaaaat acttttacaa
     3901 gttaacaccc tttatttttt taattacaac tttgttcatt gacactgcca gcgatatatt
     3961 ataaaattaa cacaataata aatattaaat ttattataca tattattaat attaattaat
     4021 ggagtaaaga tttattatat attttattta attatcctaa agtgagaaag gaagatgtga
     4081 catgaataaa aagaaaatat tagtgccaat tgatgggaca gaaagaagta tgcattcttt
     4141 ggaatttata aaaggaatat ttaaaaaaga tgaagttgaa gtagaaataa tgaatgtaaa
     4201 agaactagta tttattgatg gcatatccct ggctgaagag ataaaaaatt ctgaaaattt
     4261 aggaagaaga atcttggata aagcagcaga gataatggga gagtatgatg ttaaagtaca
     4321 ttttactttt ggatatccag gagatgagat aattagaaaa gcaaaagaag ataatgtaga
     4381 ttttatagtt atgacaaaat ctactaaaaa aggtcttaca agaatgatag gttcagtaac
     4441 agcaagtgta gttaaacaag caaaatgtat agtgatgatt gtaccggagt agaattagaa
     4501 aggtatttga aatatgaata aaaagatagt agcagtttgt gaaagtgaaa gaagtttaaa
     4561 ttctcttaag acagctgcaa atgatttagg atttgattta gtttatgaaa ttcaagaaaa
     4621 tgataatata aaaaatgaac tttctattta tgatatagaa gatgcatcca tagtgttatt
     4681 tgttacaagt gattctatag aaagcataga gaagattgat agatttatag atagagaatt
     4741 ttatgaagtt gatccaaagt atataataga ggatgcaaaa tctatagtaa gtgaaatttt
     4801 aatagactta aattaatcgt gggtgtcgca ctaagaatag agcgacgcct ttttatatat
     4861 tttacacaag aaataaagag gttgtatcaa aatatagata agagtctttt tcattgttga
     4921 aatgatgaaa atatatttga tttcatacaa aaaagagtac ctcataacta aaaagttcac
     4981 tttgagacac tccattttta tatgttagtt gcatttaagg taaaatagaa gtttaatcat
     5041 gttgaaataa ctgaattaca tcttctaaat gattgtacat tgatgtataa cctaagtaag
     5101 agtctttact atcaaatgca atcattatct tgttatggtg gctaatcata tccttgagag
     5161 aatttctata tttaaaacca aagtattggt tagaagaaac tgttttaggt attaactcat
     5221 aatattttat aaaaattgga ttatgagaag ctaaaattat ctctttgtga aattgcaagt
     5281 cagcatcata acattcttct atcaaaccat gagaaacctt atccaattcc tctattgact
     5341 ttaggtaagt atattttatt ttttgaagtt ctttagatgt agcatttaaa attgctagtt
     5401 tagtagcttc gctttcgata agttgtcttg ctcttaaaga ttctacataa aattcttgta
     5461 tgttatgatt tttatagatt tcaccatcat caaataggtc aactttttta aatccttcaa
     5521 ctataggact tgaataaggc acagctctaa gtattccttc cttacagagt atatttatgg
     5581 catttcttac aggtattcta cttatgttaa ataggtcagc aatctttctc tcacttggta
     5641 atttactatt aattttaaaa gttccattta gaatgtttaa tttaatataa tcaataattt
     5701 tttcagtggc atttaagctt ttcataaaaa ctcctaaaca tataattttt ttatgattgt
     5761 attatatcat agttaagagt taaatctact tttttataat atgtataaga caggatagag
     5821 gccaaaatag ctataatagc caagataaag tatccatatt gtattgaagt atattccgat
     5881 attttaccaa ctatcattgg aaatacagac attcctatag cataaattgc ttgaaaaaaa
     5941 cccattgcag tagatttctg atgttttggt acatttttca tagactcgct agtaaggtaa
     6001 gaaaggagta tacctgtaga tatacctggt agtacttgta gtacaaatat tatattaata
     6061 ttttttattg ttggaactaa aaagcaatag gctgaaacta aaataaaaac taaaggaatc
     6121 caaaattttg gtccatactt agtacaaaat ttagtagaag caaagccaga agaagcaaca
     6181 gcacacacca tgtaaaatat agaagataga cctatgaggg tagaactaga acctaagttt
     6241 ttaagaattt gagtagtaaa tgacattgtt gtagacattt gaataccctg ttgaattaat
     6301 gccataaagg aaaaaaatac aagtctttta tccttgcaga tagataaata ttttttaatt
     6361 gatatttttt caggtatttt tttagaatta tgatttttta tatttaaggc tagaatcgtt
     6421 ccaataactg aagacaatac actcatgata cataaggctg tcattcctaa tttttcataa
     6481 aataaagtac tcataacaaa tccaatcaac attcctagat tgtttaccaa tattatcgta
     6541 cttgtagctt tttgttgatg ttctgtagaa aaaaagttgg tatagtgaac catgtaagaa
     6601 atccaagttg atgatgatat tccagataaa atgttagcta taagaaaacc attgcctcca
     6661 ggagaaaaga ctcttataag agatgctaaa ccagcaaaga aaattccaga cagtataaat
     6721 attttatgtt tatttatgga atcagcaaat actccaacag gaagccttaa taaacattgt
     6781 gatattccat atgcacctat tattatacca atcatatttg tagatacatt acatgcactt
     6841 aaatatggat tttggaaagg tatatataca tattgtgaaa accagaaaaa tgtaacaata
     6901 gaaagtaaaa gtaatttttg attagatatt tttttcatat tatcctccat gtggtatttt
     6961 tataatgcaa ataatatacc atttagattt tttaatcaag tactttctct attaaaaaaa
     7021 atttaaatat ataattatta tttacaaaaa aattatactt tatagttgaa ttaagaaaac
     7081 gcttatgata ctataaagtt aacaaatttg aatatataac agtagacgtg ttactggtaa
     7141 tgcaggcaag atcgaatcaa tttttataga ttatctatag agtactatgg gtataatcta
     7201 tttatttggt tcgatttttt tgtttaattg gccataaaac aaaaagccta tagttgaaaa
     7261 tggaggattt tttatggatt ataaaaatat agctcaagaa attctactaa atgtaggagg
     7321 aaaagagaat gtaaatgaag tgactcattg tatgacaaga cttagattta aagtcaaaag
     7381 cgcttctaaa gtgaataagg ataaattatc taaaactgaa ggagtaataa ctgttgttga
     7441 gagtatgggt caaatacaag ttgtaattgg aaataaagta aaaaaagtat atgatgaggt
     7501 cataaaaatt gtacctcaat caaataacat aggtaaaaag aatgaaagtc aagaaaagca
     7561 aggtataatt aattctatat tatcagcagt agctggtata tttacaccta caatacctgc
     7621 tatagcaggg gttggtatga ttaaaggtat tttatcagtt cttgctatgt attatatgaa
     7681 taaaaatgga gtagatataa aagaaacgca aagctatatt atcttaaatg ctatggctga
     7741 ttctatattc tattttatgc ctattatact aggatatact gcggctaaag tatttaatgc
     7801 aaataaaata atatctatgg tattaggagc tacactttgt tatccaactt ttactgcttt
     7861 gatggcaggt gaagaatctg ttagattttt aggattggca gtaacaaaag ctacgtatac
     7921 atcatctgtt attccaataa ttattgctat atgggctctt tcatacgttg aaaaagtatt
     7981 agaaaagtat atacctgagg taattaaaat aataatggtt ccaactttat cattggtagt
     8041 aatgttacct gcaacattat ttttatttgg accaatcgga atttatatag gaaatgtcat
     8101 aaacttttct tataagtata tttatgaatt aagcccagca ttgtgtggag catttgtagg
     8161 tgggttatgg tgtgtgttag ttatatttgg tgctcataga gcattattac caataggtat
     8221 aagtgatgtt gctcaaacag gaagacaaaa tttattggcg tttgcaggag ctgcaaactt
     8281 ttcacaagca ggggctgctc taggagtatt ctttaaaact aaaaatcaag gactaaaaac
     8341 aatttctatg tctgcaacta taacagcttt atttggtata actgaacctg caatatacgg
     8401 tgccaatctt agattaaaaa aacctatggt atgtgccgta atatgtggtg catttggagg
     8461 tgcgataatg ggaatgggtg gagcttatgg taatgcattt gcaaaccaag gtgttttaac
     8521 tatacctgta tatgctgaag caggtgcatt aggtttctta agttatctag gtggttgtgc
     8581 tatagcattt tttggttcag ctatttcaac ttatctagtt ggatttgaag atttggaaga
     8641 gtcttctaat aaggaaaatt catctataaa agtagaaacg aaggatggtg ttattgatat
     8701 aacttcacct gtagagggcg aatgtataga attgtcagaa gtaaaggatg atgtatttgc
     8761 ttcaaaagct atgggagaag gtatagctgt gttacctaca aaaggagtaa taacagcccc
     8821 tactgattgt gaagtagctt ctttatttcc aacattacat gcaataggat taaaattaga
     8881 taatggagca gaaatgttaa tacatgttgg aatcaataca gtagagttaa atggtaaata
     8941 ctttacaaaa catgttaatc aaggagattt agtgaaaaaa ggtgataaac ttatatcgtt
     9001 tgatatagat aaaataaaaa aggctggtta tgatgtaact acgccagtta tagtaaacaa
     9061 tacatttgat tttgggcaag tagtttcttg taaatctagt tatgtttcaa ccaatgataa
     9121 tataatttca ttagtattag ctggtaatta agttaatttg actagagata agtaaattga
     9181 tttaaaagga aataagtaaa tcaacaatta aatacatcta aaagtaagtt tattgcaatg
     9241 aattgttaaa gaaaataatt aatatggagt aaatctattg caatgaagta acaaagaaaa
     9301 taattaatat agagtaagtt tattgtaatg aattgttaaa gaaaagagtt aatatagagt
     9361 aagtttattg taatgaattg ttaaagaaaa taattaatat agggtaaatc tatctcaatg
     9421 aaataacaaa gaaaagagtt aatatagagt gaacttattg caatgaatca acaaagaaaa
     9481 taatcaatat aaaaaggaga aatatttatg aatacaggat ttccaaaaga ctttttatgg
     9541 ggagcatcat cttctgcatt tcaagtggaa ggagcttggg ataaagacaa taaaggaaaa
     9601 accgtagccg actataattc ttttaaaaag tctcatttac aggcagatac taaagtcgca
     9661 tcagactttt accataatta tgaagaagat attgaattaa tgaaagaatt agggatgaaa
     9721 acatatcgtt tttcaatttc atgggcaaga ataataccag atggtgaagg agagataaac
     9781 cagaaaggtt tagaatttta taataagata atagacaaac tgatagagtg tgatattgag
     9841 ccattcgtaa ctttatacca ttttgacctt ccatttaaat tagtagagaa atataatggt
     9901 tgggaaagta gagaaactgt ctatgctttt gaaagatttg ctaaaatatg ctttaagcat
     9961 tttggagata gggtaaagta ttggcaacct cataatgaac agaatttaat tgttagagtg
    10021 gaggagagaa ttaatatata tgatgaaaca gattcatgga agatagataa aatgcgtgct
    10081 cagatggatt ataatctttg cttagcacat gcattagcag tcaatgcatg tcatgagatg
    10141 ataaaagaaa gtaaaattgg agcagcagta tcatcatctg taacatatcc tcttacttct
    10201 aagccagaag atgtatatgc agctagaatg aatgataatt ttaaagtgta ctatatgctt
    10261 gatatgcatc attatggaga atatccaggg tattatatga agtatcttga aaaaagaaat
    10321 atagttcctc acatggaaga tggggataaa gagatactta aaaaagctaa aatggatttt
    10381 atagctgtaa attattatag gacaaattgt gcagaagctt tacctgaaga ttcacaacat
    10441 ccatttggat taagagaagg aactgttgat tttagtatgt atggactatt taaaatgtca
    10501 atgaatccta acttagaggc ttctgagtat ggagcagcaa tagacccatc aggtcttaga
    10561 gttgccttaa atgaatattg gcaaagatat cacttacctg ttataataac agaaaatggt
    10621 ctaggagcta aagatatatt agaagatgga aaaattcatg atgactatcg tatagactat
    10681 ttaagaagtc atataaatgc atgtaaacta gctattgaag atggtgtaga gatgattgga
    10741 tattgtccat ggtcatttac agacctttta agttcttctc aaggttttaa taagcgttat
    10801 ggacttgttt atataaatag aactgaccat gaagttttag atttaaaaag aatcaagaaa
    10861 gatagttttt actggtataa agaagttata gagaacaatg gaatagtaaa ataaacataa
    10921 atatatattg agggttttag tatgtacatt acaaaggtat taaataattc gttgctactt
    10981 gcaaaggatg ataatgatga agaaataata ttgatgggga aaggcattgg ccataattat
    11041 aaggccgggt ctgagttaaa taaaaaagat atagaaaaga tttttgttct tcatgatgaa
    11101 aatataaaaa agagtattat acaattggca acagaaatag atgcagaata ttttggtata
    11161 gctcaaatga taattgcata tggaatagaa aaatataact taaaacttat gaaccatata
    11221 tatttggcct taactgacca cattgccttt gcagtgagac gttttaaaga aggtataatg
    11281 attgaaaatc actatttgtt cgaaatcaag gaatttaatc caaaagagta tgatatagga
    11341 aaatatgcta ttactgtttt taaggaggtt cttggtttag acctaccaga agaagagatt
    11401 ggtaatatag caggccattt tataaatgca caacaagata atccttatag tgatagaaat
    11461 aagagaagtg ctaaaattgt aaatgctatt ttgcaaatag ttcattatca cttttctatt
    11521 gtatataata aagagtcatt ttattatagg agatttgtaa tgcatctaaa ggccttttca
    11581 caaagatttc tggctaatga accatcaaga gaaaaaatag attttatata tgagcaagtt
    11641 caaaaaaatt gtaaggaaga gtatgaatgt gtgaaaaagg taggagctta tatgtataag
    11701 gaatactcca gagaattacc aagacaagag gagttatatt tgatgattca tattcataag
    11761 attttaggag aattatgcga aaatagttag aatatcttaa tatgctagta atattataaa
    11821 aaattaaaaa ttaactgcac tttaaatatg aataattgca ttacttaagg gggttgtctt
    11881 aaaattgatt tttttaatta aatttgaagc tcaactcctt ttttaaacct ttatatcatt
    11941 acaactttaa tgtttatacg actgtacttt agatgtatat ctacttttta catttctcaa
    12001 catgcaaacc taccattttt tgcagtatgt taattgaaat aaaccattga gttaacccta
    12061 aatttattct ggacttatag gaatagttcc aaagatactt taaaatattt tctggaataa
    12121 ttgcttattt cacatatgtt ttattgtgat gttttgattt aataaattct tcaactctgt
    12181 atatagtaaa tgtattatca tgtttgtttt attcaagcac acttataata cgcttgattt
    12241 tttcacaatg atgaaatata ctaatgggtg ttataggtat aagaatcgca ttacacttga
    12301 agaagtaagt gataaatgag gtataaatcc tcatatgata aactactatt tcattgagga
    12361 acatattcta agtgatgtca agatactaca atatgactaa attcctagtg ataaaaaagt
    12421 ctacgaatga gtgtagaaag gggaactaag atgaataaag ttttaattat agatgatgat
    12481 aaagatcttt gtattttgtt aaaaaagagt atttcaattg aacagattga agcaaactat
    12541 tgccattctg ggagagatgg actggttgaa ctttcaaaac aagattatca gttagtagtt
    12601 ctagatgtga tgatgccagg tatggatggt tttgaaacta tggaacaaat acgaaaatat
    12661 agcagtattc ccatcttaat gctgacatca aaaagcgata attacagcaa agtgcatgga
    12721 ttgcgagctg gtgcagatga ctatctaacc aaaccatttg aaattacaga atttactgct
    12781 cgtgtactgt ctttaatccg acgttacacc cgttttaatc caaaaaatga ggagccacag
    12841 caactttctt tcaaaggttt gttgattgac cttgaccagc atacagttac taccaatggc
    12901 gaacctatgt tgcttccacc caaggaattt ggtgtacttc tttactgtgc aaggcatcag
    12961 ggtaagattt tgacaaaaca gcagatttat gaagccgtgt ggggtgagcc atatgtatat
    13021 gatgacagca atatcatggc tattatcagt cgcctaagaa aaaaaattga actagaccca
    13081 tcatctccca tctatttgca aacaataaaa ggaattgggt atcaattcaa cacggaggta
    13141 tgaaaatgga tgaacaaacg ataattcttt tcttactctt gctgtcgatt ggtctacttt
    13201 ttctttccat atttgctttt tccaagcttg ggcatattta caagcgccta aaagatatag
    13261 aggagatact ggctgatgta caaattggag acgaaaatcg taaaatacta attaagccat
    13321 gtgatgttat ggctccattg gtttatcagc ttaatgagat tgtctacgat tatgaaaata
    13381 agttactttc tctgaaaaag tcggataaag ctagcaaaca acttatgaca agtttatctc
    13441 atgatgttcg tacaccatta acaactctga ttggttatct ggatgctgta cacagtggta
    13501 tagttatcga acaagagcgg gaggaatacc ttgaaatcgc taggcgtaga gcctacgacc
    13561 tcaaggatta cattgatgtt ctttttgact ggtttcggtt gaactctgat gaatttacgc
    13621 tgtcaataga atctgtggaa attgcagagt tgtcacgcaa tattttgaaa gactggattc
    13681 ctatattcca tgaaaagaaa ctgaattttg aaattgatat tccagaaaat cgactaatgg
    13741 taaacctcga cccagatgga tattcccgtg tggtcaataa tctggttcaa aatgttcttg
    13801 ctcacagtaa ggctcggcaa atcaagatta ccatgagtga ggattccaga atggtattac
    13861 tccgtgttga ggatgatggt gttgggattg ccagagaaaa tttaccacat atttttgagc
    13921 gactgtataa gtgtgataaa ggacgttcag aaaaaggaag tggtcttggt ctatctattg
    13981 tcagtcaaat ggtggagcga atgggtggtc aggtttccgt agaaagtgag attggaaagt
    14041 ataccgtatt tacagtgagc ttaccattaa tataaaattg tttttccccc atgtgacatg
    14101 tatacacatg gggatttttt gtaagttata aagttgcaag gttaatacaa ggttgttgca
    14161 aggttaatgt aagattgagg tggtatgata actttaataa acaaaggagg cttttattat
    14221 ttatgaataa tttaattatt gaaacaaaaa atctcactaa gcaatatggt gctcaaaaga
    14281 gcgtttctaa tttgaatatt cacgttcaga aaggtcgcat ttacggattg ctaggaagaa
    14341 acggtgcggg taagacgaca actatgaaaa tgttattggg tctaacaaaa ccaactactg
    14401 gagaaattaa aatatttggt caggacattc acaataacga gaagaagctt cttcctcgaa
    14461 ttggatgttt gattgaatca ccagggtttt atcctaatct gacaggaaca gaaaatctca
    14521 aaatctttgc aaggcttaga ggaataccaa aaaaaaatgc agtagaatca gcactggatg
    14581 tagtcggttt gccaaacaat gacaaaaagt tattttctca atactctctt ggtatgaaac
    14641 agaggttggc gattgctctt gccattatgc atgacccaca actgttgatt ttggacgagc
    14701 ctatcaatgg acttgatcct attggtattg cagaagtaag aacgtttatt cgtgatctct
    14761 gcacagaacg aggtaaaact attttgattt ccagtcacat tctttctgaa attgccttgt
    14821 tggcagatga cattggcatt attgaccatg gtattttgtt ggaggaagaa agtcttgccc
    14881 aattagaaga aaaaaacagt aaatacatac attttgctgt atctgatgca gcacaggcag
    14941 caaggcttct ggaaacccaa cttaacctga aaaatttcaa agtagcagat aattacaata
    15001 ttatgctata tgatacagat gtttctgttg cagaaataaa tcgtgctttc attctaaaca
    15061 acattgaggt atcagaatct catttatgcg aagatactct tgaagattac ttcaagaaag
    15121 taacaggggg tgaaggaatt gcttgatata atttcatgtg aattttcaaa actcaagcgg
    15181 ttaaaattta tactgatttc tattttaggt gcttgcttat ttccaattcc cgcaacaatt
    15241 ttgattgcaa aggacaactt gccctttgag caattgttca aattagttgt caattttgga
    15301 tattttttgc tattaccaat tgtattaagt attgttgcta gccaactatt ttttatagaa
    15361 agagataatg atgtattaaa aaatcttgca acagtgccag tgcaaaaagg aaaactggct
    15421 ctggcaaaat tggctgtgtt gctgtttata tcattgttct actctgttgc agggttagga
    15481 gctactatca ttggaggttt cattgttgga atagtagagg gggttgctgt aaaattagga
    15541 atgagcattg cttttggaat tatgtttttt gttactgtac ttcctgttgt ggtactcatt
    15601 gtatatttca atcgcagcta tattttttct attatacttt cttttgtata tgctattttc
    15661 aattttagta tatccttaaa tattatcaat tttgaaccaa ataacccaat attaagtgta
    15721 ttacctgctc ctgttataat gcgttggtgg atggcatttt ggggagatcc cactggcgaa
    15781 tacacggcac ttagacagcc atatttgctc tcaactcctg cttgtgtagg tattttatgt
    15841 ttgataacca ttatagcagt cctgctgatt tgtatgatat acaaaaagca ggagaattag
    15901 gaggtatcta tgcttgatat aattactaca gaatttcaaa aaataaaaag atataatatt
    15961 ctatggattg gtgttgttgc tgttctgttt tcagcactat tggcagtttt tcaggttgta
    16021 agttcacacg gcagtgaccc tctaacgtat gagagctttg caaacggagt tatctggaat
    16081 aatttcagtc ttagttttcc atttgggatt acacttattg gaggatatct tattaaccgt
    16141 gaatatacag accaaacctt aaaaaacatc ctaactgttc ctatttcatt acgcaaattg
    16201 ctagtgggaa aattaattgc ggttggagga attactgtat tgttaagtct tttcagcttc
    16261 ttatgcacat ttattttggg gttgttgttt tgcaatatca atatatctgt tacactcgtt
    16321 gtaaaatcct tagttcagat tttgtctgtt aatctgtatt gttatgttgc tgttttgccg
    16381 attattgctt attttggtcg taaacaaaat gcatttctga cgggtgtagg gattgcattt
    16441 gtatacggtt tttgtggtgt gtttgttgct ggaagaaatc tgacagactt ttatccaatc
    16501 acagcaggtc ttggtctagt tggatacaac aatggtgctg gtactgttta tcagccactt
    16561 atcggtgcta tgactttgat tgtaattcta atcttgacaa ctattctact tgtatttaca
    16621 cctaattatg ataaagttat gaccatatct aagaaaaaag ggataaagca taaaaagtat
    16681 tctcataaat aacataaata ttgtttctat tatttaagtt gctagacagt gaaaagaaaa
    16741 aatctgtcgt acagtgtcta tatgctcatg tattcaagaa gctacagttt tgatttttca
    16801 taactgtagc ttctttttgt atttattaaa tcacgactat cataatactt gcaataggta
    16861 tagcgacaag agagagtact gtcatatgtg ttttatatat tacattaagt atattctaaa
    16921 atatatgttt taaataatat atttgaaaat aggaatattt aaataaaaaa aataatatta
    16981 tatatagttg acaaaaattg gcaaatgaga taatatataa atatagaaat agtaatcatt
    17041 actattatta aaaagggagg aattaattat gaacttaaaa ggaactaaaa cagaaaagaa
    17101 tttaatggca ggatttgcag gagagtcaga agcaagaaat aaatatacat actacgcttc
    17161 aaaagcaaga aaagaaggtt ataatcaaat agctgctata tttgaagaaa ctgctaacaa
    17221 tgaaaaggaa catgctaaat tatggtttaa acttttacat gatggtatgc cttcaacaga
    17281 ggaaaattta aaggatgcag cagcaggtga aaactatgaa tggactgata tgtatgcaaa
    17341 atttgctaaa gaagctagag aagaaggatt tgacaagata gcttatttat ttgaagctgt
    17401 tggaaaaata gagaaagagc atgaagaaag atacttaaag cttttagaaa acttaaatga
    17461 aggaaaaata tttaaaagag atgaagaagt tgtttggcaa tgtcaaaact gtggtcatgt
    17521 gtatgtaggt actgaagcac cagaaaaatg cccagtatgt gaccatccaa aagcgtattt
    17581 caatataaaa gctgaaaatt attaaaaatt atcattatta aaaaggaatg ttaactatga
    17641 aattttctaa acaacgagaa ctgattttaa atgaaatatt aaataatccg gttcatccta
    17701 ctgcggatta cctatatgaa aacttaaaaa aagataatcc aaatttaagc ttaggaactg
    17761 tgtatagaaa tttagctcag ctaacggaac atggctttat aagaaaggtt agtattccag
    17821 ggtatccaga tagatttgat ggtcgaatag ataatcacta tcatatcata tgtgaagtat
    17881 gtggagaggt atacgattta gaatccgaag ttcttaataa tttacaagaa ttaatatctg
    17941 aggagacaga cataaaaata acatcttata acataagttt taaagggatt tgtaataatt
    18001 gtaaaaggtg tagccaagta ggttagtttt caaattctaa aaataattaa tgaggtgagt
    18061 ttatgtgtag tgaacaaaaa ttttttatat gtgagacttg tggaaacctt gtaggaatga
    18121 tacaaagtgg tggtgtacct attttctgtt gtggaaaacc tatgaaggaa cttgttccta
    18181 atacaacaga tgcagcagtt gaaaaacatg tacctgtaat tgaagtggat ggaaataatg
    18241 ttactgttaa agtaagtagc acaactcatc caatgactaa agaacatcat atagcatggg
    18301 tgtatcttat gactgaacaa ggtggtcaac gcaaatgtct agcagtagat ggagaacctg
    18361 tagttaaatt tgctttgaat gatgatgata aagtgatttc tgcctatgct tactgtaatt
    18421 tacatggatt atggaaggct gaactgtaat atttaaataa attgagtcaa aaaggaggct
    18481 ataaatgtat tttcatacaa atagcctcct ataaatttat ataaattcaa gttttaattt
    18541 tgtttaatgt caatataata taaggagaaa ataatatgtc aatttataaa tgtagtgttt
    18601 gtggatatat ttatgatgaa tctaagaatg ataaaacatg ggatgaatta agtgaagatt
    18661 gggaatgccc tgtatgtaca aaaggtcgta gttattttgg aaagataagt actgtttact
    18721 atgaagaaga tgaaaagata gcagaagaca tagttgaaga tgaatctaaa ttaaatactg
    18781 aaaaagaggg agatttaaat tacttaagta catatttaag aagagatgat gaagttgaga
    18841 aacatatgga tataattcac gaaatggctg ttacaggaaa atctataata gaacctatga
    18901 gaactaaact accagtaatt tcttgggatg atattttaat tatgggtgct caattaaatc
    18961 cattaccttt aaatgagcat gatgaagtaa atacaacaac aataatagga aaaaaagcaa
    19021 agaaacctat gattatagaa aatccagttt atatttccca catgtcattt ggagctttgt
    19081 ctaaagaact aaaaatagct ttagcaaagg gtgcagccca aaataagaca gctatgtgta
    19141 gtggtgaagg aggtatatta ccagaagaga aggaagcttc atacaagtat atttttgagt
    19201 atgtaccaaa taaatatagt gtaactgaag aaaatcttaa aaattctgat gctatagaga
    19261 taaaaattgg tcaaggaaca aaacctggta tgggaggtca tcttcctggc gaaaaagtaa
    19321 ctgaagaaat agcaaaagta agaaataagc ctgtaggtca agatgtaata agtccatctt
    19381 gttttgagga aatacaatcc aaagaagatt taaagaaact tgtagatgaa cttagagaag
    19441 tttcagaagg gcgtccaata ggtgttaaaa tttcagcagg tcatattgaa aaagatatgg
    19501 aatttatagc ttatgctaaa cctgattttg taactattga tggtcgtggt ggagctactg
    19561 gagcaagtcc aaagttgctt aaagatgcaa cttcaattcc aacaatattt gctctttatc
    19621 gtgctagaaa atacatagat acacatggat tagatataga tttggttata acaggtgggc
    19681 ttcgtatatc tactgatttt gctaaggcaa ttgctatggg tgctgatgca gttgctattg
    19741 caagttctgc tcttatggca gcggcgtgtc aacaatatcg tatatgtggt tctggtaagt
    19801 gtcctgtagg agtagctact caggatgagg aattgagaaa aagattacat atagaaaaca
    19861 gtgctaatag agtggcaaac tttttaaatg taagtttaga agaacttaag acttttgcta
    19921 gaatttctgg tcataaagat atacatgatt taagtgttga tgatttatat actgttaact
    19981 ctgaaatatc aaattataca aacatacagc atgtatagat tgaagtttga aactattaga
    20041 ttttagatag ctataaaagt aaatgataaa tatattttat aaaagagagt gtcttaaaat
    20101 gaacttttta gttcataagt cactcttttt tttatgaagc caaatatatt tatcatttta
    20161 gcaatgaaaa agaatcttat ctctttattt tgagatagac tccttctatt tatgaaaatt
    20221 aaagatatta aattgtaaaa tattctgtga tgtcgtacta ttaaactaaa gattctgtac
    20281 tttaaagtaa ataaaaattt aaggagtgat tattatggaa agattgaaga tacaagtttt
    20341 agttgacaat aatacttata ttgatagata ctttgttgga gaaccagcag taagctatta
    20401 tattgagatt gatggaaata ggattttgtt tgactcaggg tattcagatg tattcatatc
    20461 aaacgctgaa aaattaaata tagatttagg aaatttaact catgttgttt tttctcatgg
    20521 gcataatgac catacaagag gtatccagtt tctagaaaat aggtatgatt tatctacagt
    20581 tgaacttatt tcacatccta actgttttat acctagaaaa catggagaga aaagcatagg
    20641 agctccattt tctgctgagg aaattaaaaa tatttttatg tataatccta aggataagcc
    20701 atttaatcta agtaagaatt gtgtgttttt aggtgaaata ccttctataa atgattttga
    20761 aaaaagagct aaaattggta aatgtaaaat aggagatttg tgggaagatg attatgtttt
    20821 agatgattct gctatagttt gtaaaactga taaaggtatt tttattgtta caggatgttc
    20881 tcatagtgga atttgtaata tagtagagta tgctaaaaag gtatgtggag atgatagagt
    20941 tattggtata ctaggtggtt ttcatctttt tgaattgaat aataggttag atagtacaat
    21001 acaatatttg gataaagaag aaatgagaat gttgtaccct tgtcactgtg tttcttttaa
    21061 ggtaaaagcg aagatgaatg aaatattgaa tataaatgaa gttggagtag ggctgaccat
    21121 aagtatatag tatttgaaag tatataagat ttaagttgaa ggttaaaaag atattttcta
    21181 tagaaaatat cttttttgtt acgtttattt taagagaaat caatatactt ttatatgaaa
    21241 tattgtaaaa aaatttattt ttaatgagaa tatattttca ttaataaaca attttattat
    21301 gtattaataa tgttagaata aatataaata aatcaaagtt acttacatta cagtatattt
    21361 tt
//
LOCUS       DAYAOO010000071        20710 bp    DNA     linear   BCT 12-OCT-2024
DEFINITION  TPA_asm: Clostridioides difficile isolate ST8-SSI-h139-18
            SAMN40601845-rid21577343.denovo.071, whole genome shotgun sequence.
ACCESSION   DAYAOO010000071 DAYAOO010000000
VERSION     DAYAOO010000071.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN40601845
            Sequence Read Archive: SRR28438827
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 20710)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 20710)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-MAY-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-MAY-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002157583.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002157583.1
            Genome Coverage       :: 163x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/11/2024 16:19:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 4,038
            CDSs (total)                      :: 3,963
            Genes (coding)                    :: 3,930
            CDSs (with protein)               :: 3,930
            Genes (RNA)                       :: 75
            rRNAs                             :: 6, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 60
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 33
            CDSs (without protein)            :: 33
            Pseudo Genes (ambiguous residues) :: 0 of 33
            Pseudo Genes (frameshifted)       :: 7 of 33
            Pseudo Genes (incomplete)         :: 25 of 33
            Pseudo Genes (internal stop)      :: 11 of 33
            Pseudo Genes (multiple problems)  :: 8 of 33
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..20710
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN40601845-rid21577343.denovo.071"
                     /isolate="ST8-SSI-h139-18"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Denmark"
                     /collection_date="2018"
                     /collected_by="Statens Serum Institute"
     gene            370..681
                     /gene="rpsJ"
                     /locus_tag="ACGI5H_002830"
     CDS             370..681
                     /gene="rpsJ"
                     /locus_tag="ACGI5H_002830"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860633.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S10"
                     /protein_id="HFG9698527.1"
                     /translation="MAKNEKIRIRLKSYDHKLLDFSAGKIVETAKKAGSQVSGPVPLP
                     TEKQVVTILRAVHKYKDSREQFEIRTHKRLIDIANPTPKTVDSLMRLDLPAGVDIEIK
                     L"
     gene            773..1402
                     /gene="rplC"
                     /locus_tag="ACGI5H_002831"
     CDS             773..1402
                     /gene="rplC"
                     /locus_tag="ACGI5H_002831"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421173.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L3"
                     /protein_id="HFG9698528.1"
                     /translation="MKGILGKKVGMTQIFTDKGVVIPVTAVEAGPMVVTQIKTVDKDG
                     YNAIQIGFEDAKEKALNKPKKGHLAAANVLKKHLKEFRVDSVEGYTVGQEIKADVFEA
                     GAKIDVTGISKGKGFQGPIKRHGQSRGPETHGSRYHRRPGSMGACSYPGRVFKNKKLA
                     GHMGSVKVTVQNLEVVKVDADKNLILVKGAIPGAKGSVVTIKEAIKVSK"
     gene            1432..2055
                     /gene="rplD"
                     /locus_tag="ACGI5H_002832"
     CDS             1432..2055
                     /gene="rplD"
                     /locus_tag="ACGI5H_002832"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007285287.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0022625 - cytosolic large ribosomal
                     subunit [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L4"
                     /protein_id="HFG9698529.1"
                     /translation="MPKLNVLNVSGQNVGEIELSDSIFGVEVNGHVLYEVVKNQLANK
                     RQGTQSAKTRAEVRGGGRKPWKQKGTGRARQGSTRSVQWVGGGVAFAPKPRSYKYTLP
                     KKVRRLAMKSALSSKVQNSEVIVLDALNMDAPKTKEFAQILNNINAAKKALVVIADKN
                     DNVIKSARNIEGVQTALVNTMNVYDILKYDSFIITTDAVKKVEEVYA"
     gene            2055..2345
                     /gene="rplW"
                     /locus_tag="ACGI5H_002833"
     CDS             2055..2345
                     /gene="rplW"
                     /locus_tag="ACGI5H_002833"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435681.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L23"
                     /protein_id="HFG9698530.1"
                     /translation="MTNPHDVIIRPVVTEHSMAEMGEKKYTFVVAKDANKTEIKKAVE
                     KVFGVSVDKVNTLNYDGKVKRMGRTQGRTSSFKKAVVKLTADSKEIEFFQGM"
     gene            2375..3205
                     /gene="rplB"
                     /locus_tag="ACGI5H_002834"
     CDS             2375..3205
                     /gene="rplB"
                     /locus_tag="ACGI5H_002834"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421168.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0015934 - large ribosomal subunit
                     [Evidence IEA];
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_function: GO:0016740 - transferase activity [Evidence
                     IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L2"
                     /protein_id="HFG9698531.1"
                     /translation="MAIKKFRPTSPALRQMTVLVSDEITCNQPEKSLLVNLKKNAGRN
                     VHGRITVRHRGGGQKRKYRIIDFKRDKDGIPAKVATIEYDPNRTANIALLNYADGEKR
                     YILAPVGINVGDTILSGLGADIKPGNCLALKDMPVGTIIHNIELKPGKGAQLVRSAGV
                     SAQLMAKEGKNALLRLPSGEMRLVSINCKATIGQVGNIEHGNVVIGKAGRKRHMGIRP
                     TVRGSVMNPNDHPHGGGEGRSPIGRPSPVTPWGKPALGYKTRKKNKASNKLIVSRRTK
                     "
     gene            3240..3521
                     /gene="rpsS"
                     /locus_tag="ACGI5H_002835"
     CDS             3240..3521
                     /gene="rpsS"
                     /locus_tag="ACGI5H_002835"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007285290.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0015935 - small ribosomal subunit
                     [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S19"
                     /protein_id="HFG9698532.1"
                     /translation="MSRSTKKGPFVHARLLKKIEAMNASGNKEVIKTWSRSSTVFPQM
                     VENTIAVHDGRKHVPVYITEDMVGHKLGEFVPTRTFKGHKDDEKSNKRK"
     gene            3553..3888
                     /gene="rplV"
                     /locus_tag="ACGI5H_002836"
     CDS             3553..3888
                     /gene="rplV"
                     /locus_tag="ACGI5H_002836"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018590372.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0015934 - large ribosomal subunit
                     [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L22"
                     /protein_id="HFG9698533.1"
                     /translation="MEAKATAKYVRVSPRKAGQICDLVRGKNVDEALAILKFTPRGAA
                     SIIAKVVKSAKANAENNHEMDTEKLYIASIVANQGPTMKRFMPRAMGRATTIRKRTSH
                     IEVVVKEKK"
     gene            3911..4726
                     /gene="rpsC"
                     /locus_tag="ACGI5H_002837"
     CDS             3911..4726
                     /gene="rpsC"
                     /locus_tag="ACGI5H_002837"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421163.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S3"
                     /protein_id="HFG9698534.1"
                     /translation="MGQKVNPHGLRVGVIKDWDSRWFATDKKEFGNLLLEDHNIRKFL
                     KKRLYSAGVAKIEIERSANKIKMDLHVAKPGVVIGRAGAGIEALKAELEKMTKKTIIV
                     NIVEVRSTDKNAQLVAENIALAIERRVAFRRAMKQAIQRAMKSGAKGIKVSASGRLGG
                     AEMARTEGYSEGNVPLQTLRADIDYGFAEADTTYGKIGIKVWICNGEVLPTRDGVNPR
                     EESRKSDRRDNKRDNRRNDRRGNDRRGNDNRGNYRGQRPQGGSRPQRTENKGN"
     gene            4762..5193
                     /gene="rplP"
                     /locus_tag="ACGI5H_002838"
     CDS             4762..5193
                     /gene="rplP"
                     /locus_tag="ACGI5H_002838"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421160.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_function: GO:0019843 - rRNA binding [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L16"
                     /protein_id="HFG9698535.1"
                     /translation="MLMPKRVKRRRVHRGSMAGQAHKGNKVTYGEFGLVALEASWITS
                     NQIEAARIAMTRYIKRGGKVWIKIFPHKPVTRKPAETRMGAGKGSPEYWVAVVKPGRV
                     MFELAGVSEDKAREAMRLAAHKLPIKCKFVKKEDLEVKGGE"
     gene            5195..5398
                     /gene="rpmC"
                     /locus_tag="ACGI5H_002839"
     CDS             5195..5398
                     /gene="rpmC"
                     /locus_tag="ACGI5H_002839"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018590375.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L29"
                     /protein_id="HFG9698536.1"
                     /translation="MKAKELRDLTSEELMNKLNDFKSELFSLRFQLATGQLENTARIK
                     FVKKDIAKVKTVLAERKLYETRA"
     gene            5422..5676
                     /gene="rpsQ"
                     /locus_tag="ACGI5H_002840"
     CDS             5422..5676
                     /gene="rpsQ"
                     /locus_tag="ACGI5H_002840"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018590376.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S17"
                     /protein_id="HFG9698537.1"
                     /translation="MERGRRKVRIGRVVSDKMDKTIVVAVEEFVRHPLYNKRVKRTKK
                     FKAHDEKNICNIGDRVKIMETRPLSKDKRFRLVEVVEKVK"
     gene            5702..6070
                     /gene="rplN"
                     /locus_tag="ACGI5H_002841"
     CDS             5702..6070
                     /gene="rplN"
                     /locus_tag="ACGI5H_002841"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012727667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0015934 - large ribosomal subunit
                     [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L14"
                     /protein_id="HFG9698538.1"
                     /translation="MIQQESRLRVADNSGAKELLCIRVLGGSKRRYGNIGDVIVATVK
                     SATPGGVVKKGKVVKAVIVRSKQGVRRNDGSYISFDENAAVIIKDDKTPVGTRIFGPV
                     ARELRDNEFMKIVSLAPEVL"
     gene            6094..6399
                     /gene="rplX"
                     /locus_tag="ACGI5H_002842"
     CDS             6094..6399
                     /gene="rplX"
                     /locus_tag="ACGI5H_002842"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427723.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L24"
                     /protein_id="HFG9698539.1"
                     /translation="MRVKKGDTVVVIAGKDKGKKGSVLKVYPKTSKVLVEGVNVITKH
                     QKPSAMNQQGGIINKEAPIHISNVMPFDPETGKGVRVRYEVKDGNKVRVSAKSGKEL"
     gene            6429..6971
                     /gene="rplE"
                     /locus_tag="ACGI5H_002843"
     CDS             6429..6971
                     /gene="rplE"
                     /locus_tag="ACGI5H_002843"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018590379.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L5"
                     /protein_id="HFG9698540.1"
                     /translation="MASRLQEKYMKEVAPALMEKFGYKNVMEIPKLNKIVINMGIGDA
                     RENPKGLEKGVEELEMISGQKPVITKARKSVANFKLREGMPIGTKVTLRADKMFYFMD
                     KLVSVSLPRVRDFRGVNPNAFDGRGNYALGVKEQLIFPEIEYDKIDKVRGMDIIFVTT
                     AKTDEEARELLKLLGMPFSK"
     gene            6989..7174
                     /locus_tag="ACGI5H_002844"
     CDS             6989..7174
                     /locus_tag="ACGI5H_002844"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011245027.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type Z 30S ribosomal protein S14"
                     /protein_id="HFG9698541.1"
                     /translation="MARKAMVVKQQRKQKYATREYTRCTICGRPHSVLKKFGICRICF
                     RELAYKGQIPGVRKASW"
     gene            7207..7605
                     /gene="rpsH"
                     /locus_tag="ACGI5H_002845"
     CDS             7207..7605
                     /gene="rpsH"
                     /locus_tag="ACGI5H_002845"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003241998.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S8"
                     /protein_id="HFG9698542.1"
                     /translation="MTMTDPIADMLTRIRNANVVKHETVDVPASNMKKELARILLEEG
                     FIRGYDVIEDGKQGIIRIQLKYGQEGERVITGLKKISKPGMRVYAANHEIPKVLNGLG
                     ISVISTSKGILTDKQARKENVGGEVICYVW"
     gene            7636..8178
                     /gene="rplF"
                     /locus_tag="ACGI5H_002846"
     CDS             7636..8178
                     /gene="rplF"
                     /locus_tag="ACGI5H_002846"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421144.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_function: GO:0019843 - rRNA binding [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L6"
                     /protein_id="HFG9698543.1"
                     /translation="MSRIGVKPIIIPAGVEVTIAEGNLVTVKGPKGTLTKQLSAELNI
                     KKEENTIMVERPTDNKKHRSLHGLTRTLLDNMVVGVNTGFEKKLELKGVGYRAQKQGK
                     KLVMNLGFSHPVEMEDPEGITVEAPNQTELIVKGIDKQLVGNYAAKIRAWRKPEPYKG
                     KGIKYVDEVIRRKEGKTGKK"
     gene            8214..8582
                     /gene="rplR"
                     /locus_tag="ACGI5H_002847"
     CDS             8214..8582
                     /gene="rplR"
                     /locus_tag="ACGI5H_002847"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007285302.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L18"
                     /protein_id="HFG9698544.1"
                     /translation="MLKKADKNANRLQRHKRVRRKISGTSQRPRLCVFRSANNIYAQI
                     IDDTKRVTLVAASSLEAEVKSAVNHTGNKEAAKKVGELVAKKAVEKGITEVVFDRGGY
                     LYHGRIQELAEGAREAGLKF"
     gene            8603..9112
                     /gene="rpsE"
                     /locus_tag="ACGI5H_002848"
     CDS             8603..9112
                     /gene="rpsE"
                     /locus_tag="ACGI5H_002848"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421138.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0015935 - small ribosomal subunit
                     [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S5"
                     /protein_id="HFG9698545.1"
                     /translation="MLRRKPIDAGQLDLQEKVVEVRRVTKVVKGGRNFRFAALVVVGD
                     ENGHVGIGAGKAMEVPDAIKKAVEDAKKNLIVVPIVGTTIPHEVRGHFGAGNILIMPA
                     VEGTGVIAGGPARAVLELAGLKDVRAKSLGSNNPRNMVNATIEGLNSLKTVEDIAKLR
                     GKKVEELLG"
     gene            9127..9312
                     /gene="rpmD"
                     /locus_tag="ACGI5H_002849"
     CDS             9127..9312
                     /gene="rpmD"
                     /locus_tag="ACGI5H_002849"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421137.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0015934 - large ribosomal subunit
                     [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L30"
                     /protein_id="HFG9698546.1"
                     /translation="MAKLQIKLVRSVIGTTPNQKKNVEALGLRKREQVVVKEDNAQTR
                     GMINKVSHLLEVTEIAE"
     gene            9345..9788
                     /gene="rplO"
                     /locus_tag="ACGI5H_002850"
     CDS             9345..9788
                     /gene="rplO"
                     /locus_tag="ACGI5H_002850"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006440517.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0015934 - large ribosomal subunit
                     [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L15"
                     /protein_id="HFG9698547.1"
                     /translation="MKLHELKPAEGAVRAKRRLGRGTATGQGKTAGRGQKGQWSRSGG
                     GVRVGFEGGQMPLARRLPKRGFNNIFKKVYTEVNVEVLNRFENGTEITAELLKSTKTI
                     SKIGKDGIKILGEGNLEKALTVKAAKFTASAQEKIEKAGGKAELV"
     gene            9832..11100
                     /gene="secY"
                     /locus_tag="ACGI5H_002851"
     CDS             9832..11100
                     /gene="secY"
                     /locus_tag="ACGI5H_002851"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421133.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_process: GO:0015031 - protein transport [Evidence IEA];
                     GO_process: GO:0043952 - protein transport by the Sec
                     complex [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecY"
                     /protein_id="HFG9698548.1"
                     /translation="MLSKLKQAWKIKAVRKKVMYTLMMIVIFRIGTTIPVPGIDTSII
                     QKMVGGNSLLSLYNMFTGGAFSNFSLFALGISPYITASIIIQLLTVGFESLAELQKSG
                     EEGKKKINKYTKYTALALAVVQALGITLGIVRSALISNSVFFITTVVITLVSASMLVM
                     WIGDKITEKGIGNGSSVIIFAGIISRIPTDVIKISQQVKSGEVAPWVIVILAVVILLT
                     VTGVTFIQEATRKIPVQYAKRVVGRKMYGGQSSHIPMKVNQSGVMPIIFASSLLAFPQ
                     TIAMFMGPNAQAFVQKYLSMATEQGFWTYRSIEILLIIFFSYFYTTVSFNTEDISKNM
                     KNNGGFIPGIRPGEPTMDYLNRILTRLTLAGATFLAIIAMVPALTTHYMKVNMSLAGT
                     SLLIVVGVALELKRQLESNLVMRSYQGFLK"
     gene            11117..11767
                     /locus_tag="ACGI5H_002852"
     CDS             11117..11767
                     /locus_tag="ACGI5H_002852"
                     /EC_number="2.7.4.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009904768.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016776 - phosphotransferase activity,
                     phosphate group as acceptor [Evidence IEA];
                     GO_function: GO:0019205 - nucleobase-containing compound
                     kinase activity [Evidence IEA];
                     GO_process: GO:0006139 - nucleobase-containing compound
                     metabolic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="adenylate kinase"
                     /protein_id="HFG9698549.1"
                     /translation="MRIILLGPPGAGKGTQAAGIVEKYNIPHISTGDIFRKNIKEGTE
                     LGKKAKEYMDQGLLVPDELTVGLVTDRISQEDCKNGFMLDGFPRNVAQGEHLDIFLKN
                     AGISLDKVVNIEVDKSILVSRAVGRRICKSCGATYHVEFNPPKVEGVCDVCQGELYQR
                     ADDNEETVSKRIQVYLDETKPLVDYYSKQGIIADIKGDQAIDKVFEDIVAALGSGK"
     gene            11768..12514
                     /gene="map"
                     /locus_tag="ACGI5H_002853"
     CDS             11768..12514
                     /gene="map"
                     /locus_tag="ACGI5H_002853"
                     /EC_number="3.4.11.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421130.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0070006 - metalloaminopeptidase activity
                     [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type I methionyl aminopeptidase"
                     /protein_id="HFG9698550.1"
                     /translation="MIILKSKKEIELLREAGKIVADTHEVLRKAISPGISTLELDKIA
                     EENIRKYNAEPSFKGYGGFPGSICASINREVVHGIPGETILQEGDIVSLDIGAYYKGY
                     HGDSAKTHGVGMISEEDRKLIEVTRESFYEGIKFAKLGYRLSDISHAVQTHVEKHGFS
                     VVRDLVGHGVGANLHEDPQVPNYGLPGKGPRLREGMVIAIEPMVNAGRYHVKTLSDGW
                     TTVTIDGKKSAHYEHTIAITEHEPLILTKL"
     gene            12536..12805
                     /locus_tag="ACGI5H_002854"
     CDS             12536..12805
                     /locus_tag="ACGI5H_002854"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="KOW domain-containing protein"
                     /protein_id="HFG9698551.1"
                     /translation="MLSDNLSIGQVVKVSLGRDKGNLFFVVKIINNEYVLIADGKKRK
                     LDKPKLKKVKHLKKYNFINDEVRKRVVSGQEITDSFLRAELTKLN"
     gene            12843..13061
                     /gene="infA"
                     /locus_tag="ACGI5H_002855"
     CDS             12843..13061
                     /gene="infA"
                     /locus_tag="ACGI5H_002855"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017185218.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003743 - translation initiation factor
                     activity [Evidence IEA];
                     GO_process: GO:0006413 - translational initiation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="translation initiation factor IF-1"
                     /protein_id="HFG9698552.1"
                     /translation="MAKKDVIELEGTVSEALPNAMFKVKLENGHEILCHISGKLRMNF
                     IRILEGDKVNVELSPYDLTRGRITWRKK"
     gene            13097..13210
                     /gene="rpmJ"
                     /locus_tag="ACGI5H_002856"
     CDS             13097..13210
                     /gene="rpmJ"
                     /locus_tag="ACGI5H_002856"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003720928.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L36"
                     /protein_id="HFG9698553.1"
                     /translation="MKVRPSVKPICEKCKVIKRKGKVMVICENPKHKQKQG"
     gene            13363..13734
                     /gene="rpsM"
                     /locus_tag="ACGI5H_002857"
     CDS             13363..13734
                     /gene="rpsM"
                     /locus_tag="ACGI5H_002857"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012065416.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S13"
                     /protein_id="HFG9698554.1"
                     /translation="MARIAGVDLPREKRAEIGLTYIYGIGKATANEILAKAEINPDTR
                     IKDLSEDQVNELRKVIDDDFLVEGDLRREIALNIKRLRDIKCYRGIRHAKGLPLRGQR
                     TKTNARTRKGPRKTVSRKKKK"
     gene            13770..14168
                     /gene="rpsK"
                     /locus_tag="ACGI5H_002858"
     CDS             13770..14168
                     /gene="rpsK"
                     /locus_tag="ACGI5H_002858"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020449874.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S11"
                     /protein_id="HFG9698555.1"
                     /translation="MAKPKKKVTRIRRRERKNIERGHAHIQSTFNNTIITLTDVHGNA
                     ISWASSGQLGFKGSRKSTPFASQMAAETAAKAAMEHGLKSVEVFVKGPGSGREAAIRA
                     LQATGLEVTMIKDVTPIPHNGCRPPKRRRV"
     gene            14200..14823
                     /gene="rpsD"
                     /locus_tag="ACGI5H_002859"
     CDS             14200..14823
                     /gene="rpsD"
                     /locus_tag="ACGI5H_002859"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421121.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0015935 - small ribosomal subunit
                     [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_function: GO:0019843 - rRNA binding [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S4"
                     /protein_id="HFG9698556.1"
                     /translation="MARYTGASCRQCRREGMKLFLKGDRCYTDKCAIVKRNYAPGQHG
                     QGRKKVSNYGLQLREKQKVKRIYGVLETQFRNLYERAENMPGKAGENLLSLLERRLDN
                     VVYRMGLASSRKEARQLVTHGHFTLNGNKVDIPSLIVKVGDVIEVKEKSRSSAKFKNL
                     VEVNSRIAPKWLEANVEGMTAKVVGVPTREDIDLEIAEHLIIELYSK"
     gene            14901..15848
                     /locus_tag="ACGI5H_002860"
     CDS             14901..15848
                     /locus_tag="ACGI5H_002860"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427733.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003899 - DNA-directed 5'-3' RNA
                     polymerase activity [Evidence IEA];
                     GO_function: GO:0046983 - protein dimerization activity
                     [Evidence IEA];
                     GO_process: GO:0006351 - DNA-templated transcription
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit alpha"
                     /protein_id="HFG9698557.1"
                     /translation="MIEIEKPKVDIVELSEDYRYGKFVIEPLERGYGITIGNALRRIL
                     LSSLPGVAVNAIKIDGVLHEFSTIPGVKEDVTEIILTLKELSATIDGEGSRTLKIEAQ
                     GPCSITGADIICPPDVEILSKDLAIATLDDNAKLNMEIFVDKGRGYVSAEENKTENVP
                     IGVLPVDSIYTPVEKVSYHVENTRVGQKTDYDKLVLEVWTNGSINPQEGISLAAKVLV
                     EHLNLFIDLTEHVSSVEIMVEKEEDQKEKVLEMTIEELDLSVRSYNCLKRAGINTVEE
                     LANKSEDDMMKVRNLGKKSLEEVIQKLEELGLGLKPSEE"
     gene            15869..16210
                     /gene="rplQ"
                     /locus_tag="ACGI5H_002861"
     CDS             15869..16210
                     /gene="rplQ"
                     /locus_tag="ACGI5H_002861"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421117.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L17"
                     /protein_id="HFG9698558.1"
                     /translation="MAKYRKLGRETAHRNLMLRNLVTCLLRSGRIETTVTRAKETRRM
                     AEKMITLAKRGDLHARRQVLAYVMDETVVNNLFTDLAPKYAERNGGYTRIIKIGPRKG
                     DAAEMAFIELV"
     gene            16330..17163
                     /locus_tag="ACGI5H_002862"
     CDS             16330..17163
                     /locus_tag="ACGI5H_002862"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435660.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009898 - cytoplasmic side of plasma
                     membrane [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0006810 - transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor transporter ATPase"
                     /protein_id="HFG9698559.1"
                     /translation="MDNIVKVNNISFEYITDEAKLKAIDNLSLDVKKGEFVAIIGHNG
                     SGKSTLSKNLNAILMPTEGNILIDDMDTKEEERLWDIRQTAGMVFQNPDNQIVATIVE
                     EDVAFGPENLGIEPKEIRRIVEESLKSVGMYDLRDRQPHLLSGGQKQRVAIAGIIAMR
                     PKCIIFDEATAMLDPSGRKEVMKTIKRLNKEENITVIHITHFMEEAVEADRVVVMEKG
                     KKILEGTPREVFSKIKMLKEIGLDVPCMTELSSLLIEEGINISSDILTVDEMVMELCQ
                     L"
     gene            17151..18017
                     /locus_tag="ACGI5H_002863"
     CDS             17151..18017
                     /locus_tag="ACGI5H_002863"
                     /EC_number="3.6.3.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427735.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor transporter ATPase"
                     /protein_id="HFG9698560.1"
                     /translation="MSIIVKNLTHIYNEGMPFASKALDDVSFEIKDRDFVGLIGHTGS
                     GKSTLIQHLNGLLKPSSGEIFINDFNITDKNLNLTEIRKRVGVVFQYPEYQLFEETID
                     KDIAFGPSNLGLEESEIHNRVKASMEAVGLDYEGFKDKSPFELSGGQKRRVAIAGVIA
                     MNPEVLILDEPTAGLDPGGRDEIFNLIKDLHEKKNMTIILSSHSMDDMAKLAKTLIVM
                     NHGSVEFMGTPREVFKSNASKLKDIGLDIPQVLELALKLREKGFDISEDILTLEEAKQ
                     EILKVVRGRGLC"
     gene            18011..18814
                     /locus_tag="ACGI5H_002864"
     CDS             18011..18814
                     /locus_tag="ACGI5H_002864"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860635.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor transporter transmembrane
                     protein EcfT"
                     /protein_id="HFG9698561.1"
                     /translation="MLKDITIGQYYPTSSAIHKLDPRIKLVATIVFMVSIFVVNKFWP
                     YIVVLLCLLAMIKLANIPVKYIVKGVKPLKWIILFTFLINIFFLPGDEIWSFGFLAIT
                     KQGLRQAIFMAIRLIFLVVGTSLLTLTTSPIELTDGIERLLNPFKKIGLPVHELAMMM
                     TIALRFIPTLLDETDKIMKAQMSRGADFESKNLINRAKNLVPLLVPLFVSAFRRADEL
                     AMAMEARCYRGGHNRTKMRESVISRRDYMACVFQVVYLGAIIATRFIAI"
     gene            18846..19577
                     /gene="truA"
                     /locus_tag="ACGI5H_002865"
     CDS             18846..19577
                     /gene="truA"
                     /locus_tag="ACGI5H_002865"
                     /EC_number="5.4.99.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435654.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0009982 - pseudouridine synthase activity
                     [Evidence IEA];
                     GO_process: GO:0001522 - pseudouridine synthesis [Evidence
                     IEA];
                     GO_process: GO:0009451 - RNA modification [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA pseudouridine(38-40) synthase TruA"
                     /protein_id="HFG9698562.1"
                     /translation="MRNIKIKIQYNGKNYCGWQKQPDSLGIQGTIERAIYDITKEETS
                     LIGSGRTDSGVHAIGQIANFKINSGISIESIPMALNAKLPKDISVIEACEVNDDFHSR
                     YSAKGKTYKYLVYNSKFRNPILSEISYQVKYELDFDKMCSEAKSLLGTHDFKGFMSSG
                     SSVKDTVRTIYDIDISKKDDLITFEISGNGFLYNMVRIIVGTLVDMGRGRINEPFLDI
                     IQSKTRSRCGHTAPAQGLFLKKVHY"
     gene            19697..20128
                     /gene="rplM"
                     /locus_tag="ACGI5H_002866"
     CDS             19697..20128
                     /gene="rplM"
                     /locus_tag="ACGI5H_002866"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435651.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L13"
                     /protein_id="HFG9698563.1"
                     /translation="MKSYIAKPADVQRKWYLVDAEGKTLGRLATEIATVLRGKHKPTF
                     TPHVDGGDFVVVVNAEKIVLSGKKLDQKYYRYHTGYVGGLKEISYRDMMDKKPEEVIS
                     HAVSGMLPKNKLRSRMMTRLRVFAGAEHTHAAQNPEVLNFK"
     gene            20157..20549
                     /gene="rpsI"
                     /locus_tag="ACGI5H_002867"
     CDS             20157..20549
                     /gene="rpsI"
                     /locus_tag="ACGI5H_002867"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421105.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S9"
                     /protein_id="HFG9698564.1"
                     /translation="MANVQYYGTGRRKSSVARVRLVAGEGNILVNGRALENYFNYETL
                     IRDVKQPLVLTGNENKYDVIVKVEGGGFTGQAGAIRHGISRALLKADLDLRPALKKEG
                     FLTRDARMKERKKYGLKAARRAPQFSKR"
BASE COUNT         8269 a         2445 c         4321 g         5675 t
ORIGIN      
        1 ctttactaaa ctaatggatt taatataaaa aaaagagggg gtaactcctc tcttttttgt
       61 tttttgttga caagtagcgc taaagcatat atactaaact agtgccttga gacagattaa
      121 caatcaagtt taaggttatg atgttgtaat agaaaataaa attgaaaaaa acagaaaaaa
      181 aacttgaaaa aatgtaacag atgatataaa atataatagt gtgcttgaga gattaagaaa
      241 ataataatta aatcctagtg aaatacgaac tgatatcgat ttaaaagtta caacacaccc
      301 ggagcagtgt atcggtattg gttgtacgca acttgaaaat taaacacgtg ataaaggagg
      361 gaaaacaaaa tggctaagaa tgaaaaaata agaataagat taaaatcata tgatcacaaa
      421 ttattagatt tttcagcagg taaaatagtt gaaactgcta aaaaggctgg atcacaagtt
      481 tcaggacctg tgcctctacc aacagaaaaa caagttgtaa ctatattaag agctgtacat
      541 aagtacaaag actctagaga acaatttgaa ataagaactc ataaaagact aatcgacata
      601 gctaatccaa cacctaagac agttgactca ttaatgagat tagacttacc agcaggtgta
      661 gatatagaaa taaaattata agaaccccta agatattatc ctatagatga ttatcttaga
      721 atgattactc taaaagatgt aatccgctgt aagaattata ggaggtgcta atatgaaagg
      781 aatattaggc aaaaaagttg gtatgactca aatattcact gataaaggtg tagttatacc
      841 tgtaacagct gttgaagcag ggcctatggt cgttactcaa ataaaaacag ttgataaaga
      901 tggatacaat gctatacaaa taggttttga agatgctaaa gaaaaagctt taaacaaacc
      961 taaaaaagga catttagctg ctgctaatgt tttaaagaaa catttaaaag aatttagagt
     1021 agattctgta gaaggataca cagtaggaca agaaataaaa gctgatgtat ttgaagcagg
     1081 tgcaaaaata gatgttactg gaataagtaa aggtaaggga ttccaaggtc caataaaaag
     1141 acatggacaa agtagaggtc ctgaaactca cggttctaga taccacagaa gaccaggttc
     1201 aatgggagct tgttcttacc caggtagagt atttaaaaac aaaaaattag ctggacatat
     1261 gggaagcgta aaggtaacag ttcaaaactt agaggttgtt aaagtagatg ctgacaagaa
     1321 ccttatatta gttaaaggag ctataccagg agctaaaggt tcagtagtaa ctataaaaga
     1381 agctataaag gtttctaaat aatgactaac ctagagaaag gaggaataac aatgccaaaa
     1441 ttaaatgtac taaatgttag tggacaaaac gttggagaaa tagaattatc agattctata
     1501 tttggcgtag aagttaatgg acatgtttta tacgaagttg taaaaaatca attagcaaat
     1561 aagagacaag gaactcaatc tgctaaaact agagcagaag ttagaggtgg cggaagaaaa
     1621 ccttggaaac aaaaaggaac aggtagagca agacaaggtt ctacaagatc tgtacaatgg
     1681 gtaggtggag gagttgcttt tgcacctaaa ccaagaagct acaaatatac attacctaag
     1741 aaggtaagaa gattagctat gaagagtgct ttatcttcaa aagttcaaaa tagtgaagtt
     1801 atagtattag atgcattaaa catggatgct cctaagacta aagaatttgc tcaaatatta
     1861 aacaatataa atgctgctaa aaaagcttta gtagttatag ctgacaaaaa cgataacgta
     1921 ataaaatcag ctagaaatat agaaggtgtt caaactgcat tagttaatac tatgaatgta
     1981 tatgatatat taaaatacga ttcatttata ataactacag atgctgttaa aaaagtggag
     2041 gaggtgtacg cataatgact aatccacatg atgtaataat aagaccagtt gtaactgagc
     2101 acagtatggc tgaaatgggt gaaaaaaaat acacttttgt tgtggctaaa gatgcgaaca
     2161 aaactgaaat aaaaaaagca gtagaaaaag tattcggagt tagtgttgat aaagtaaata
     2221 ctttaaacta cgatggaaaa gttaaaagaa tgggtagaac tcaaggaaga acatcaagct
     2281 ttaagaaagc agtagttaaa ttaactgctg atagtaaaga aatagaattc ttccaaggaa
     2341 tgtagtatta taacaaacga aggagggaaa acagatggct ataaaaaagt ttagaccaac
     2401 ttctcctgcc ttaagacaaa tgacagtttt agtttctgat gaaataacat gtaatcaacc
     2461 agaaaaatct cttttagtta acttaaagaa aaatgctggt agaaacgtac atggtagaat
     2521 aactgttcgt catagaggtg gaggacaaaa aagaaaatat agaataatag attttaaaag
     2581 agataaagat ggtatacctg ctaaggttgc tactatagaa tatgatccaa acagaactgc
     2641 aaatatcgca ttattaaact atgctgatgg agaaaaaaga tatatattag ctccagttgg
     2701 aattaacgtt ggagatacta tattatcagg attaggtgct gatataaaac caggaaactg
     2761 tttagcatta aaagatatgc cagttggtac tatcattcat aatatagaat taaagccagg
     2821 aaaaggagct caattagtta gatctgctgg agtttctgca caattaatgg ctaaagaagg
     2881 aaaaaatgct ttattaagat taccatcagg tgagatgaga ttagtaagca taaactgtaa
     2941 agctactata ggtcaagttg gaaatataga gcatggtaac gtagttatcg gtaaagcagg
     3001 tagaaaaaga catatgggaa taagacctac tgtaagaggt tctgtaatga accctaatga
     3061 ccatccacac ggtggagggg aaggtagatc tccaataggt agaccatctc ctgttactcc
     3121 atggggtaaa ccagctcttg gatacaaaac tagaaagaaa aataaagctt caaataaact
     3181 aatagtatca agaagaacta agtagtaaat ttatttttgc tcggaaagga ggaatataaa
     3241 tgtcaagatc aactaaaaaa gggccttttg tccatgcaag acttttaaag aagatagaag
     3301 ctatgaatgc tagtggaaat aaagaagtta taaaaacttg gtcaagatct tcaactgtat
     3361 ttccacaaat ggtagaaaac actatagctg ttcatgatgg aagaaaacat gttccagtat
     3421 atataacaga agatatggtt ggacataaat taggtgagtt cgttcctact agaactttca
     3481 aaggacataa ggatgacgaa aaatctaata agagaaaata attaaattat gactaagaaa
     3541 ggaggaataa caatggaagc aaaagctact gctaaatacg tacgtgtatc accaagaaaa
     3601 gcaggccaaa tatgtgacct tgttagagga aagaatgttg atgaagcatt agcaatatta
     3661 aagtttactc caagaggagc agcttcaata atagctaagg ttgtaaaatc agctaaagct
     3721 aacgcagaaa acaatcacga aatggatact gaaaaattat atatagcatc aatagttgct
     3781 aatcaaggac caacaatgaa gagattcatg cctagagcta tgggtcgtgc aactacaata
     3841 agaaaaagaa cttctcatat agaggttgtt gttaaagaaa aaaaataatt aatagatagg
     3901 agggaaagta atgggtcaaa aggttaatcc acacggctta agggtcggtg ttataaaaga
     3961 ttgggactca agatggttcg ctactgataa aaaagagttc ggaaacttat tattagaaga
     4021 ccataatata cgtaaattct taaagaaaag attatactca gctggagttg ctaagataga
     4081 aatagaaaga tcagctaaca aaataaaaat ggacttacac gttgctaagc ctggtgtagt
     4141 tataggaaga gctggtgcag gaatcgaagc attaaaagct gaattagaaa aaatgacaaa
     4201 gaaaactata atagttaata tagtagaagt aagaagtaca gataaaaatg ctcaattagt
     4261 agctgagaat atagctttag ctatagagag aagggttgct ttcagaagag caatgaaaca
     4321 agctatacaa agagcaatga aatctggtgc taaagggata aaagtttctg cttcaggaag
     4381 attaggtgga gctgaaatgg ctagaactga aggttatagt gaaggaaatg tgccactaca
     4441 aactttaaga gcagatatag attatggttt cgctgaagct gatacaactt atggaaaaat
     4501 cggtataaaa gtttggatat gtaatggtga agttttacca actagagacg gtgtaaatcc
     4561 aagagaagaa agcagaaaga gcgatagaag agacaacaag agagataata gaagaaacga
     4621 tagaagagga aatgacagaa gaggaaatga taacagagga aactacagag gacaaagacc
     4681 tcaaggtgga tcaagacctc aaagaactga aaacaaagga aattaataat agttaggttc
     4741 aaggaaggag gaaaaatact catgttaatg ccaaaaagag taaagcgtcg tagagttcat
     4801 agaggaagca tggctgggca agctcataag ggtaataaag ttacttatgg tgagtttgga
     4861 ttagtagcat tagaagcttc ttggataact tctaatcaaa tagaagctgc cagaatcgcg
     4921 atgactagat atataaaaag agggggaaag gtttggataa aaatattccc tcataaacca
     4981 gtaacaagaa aaccagcaga gactcgtatg ggtgcaggga aaggttctcc agaatattgg
     5041 gtagctgtag ttaagccagg aagagttatg tttgaattag caggtgtttc tgaagataaa
     5101 gcaagagaag ctatgagact tgctgcacat aaattaccaa tcaaatgtaa atttgttaaa
     5161 aaagaagatt tagaagtaaa gggtggtgaa taggatgaaa gctaaagaat taagagattt
     5221 aacaagcgaa gagctaatga acaaattaaa cgacttcaaa agtgaattat ttagcttaag
     5281 attccaatta gctactggtc aattagaaaa tacagctaga ataaagtttg ttaagaagga
     5341 tatagcaaaa gttaaaactg ttcttgctga aagaaagtta tacgaaacta gagcttaatt
     5401 tggaaaggag gctttttaaa catggaaaga ggaagaagaa aagttagaat aggccgtgtt
     5461 gttagtgata agatggataa aacaatagta gtagctgttg aagaattcgt acgtcatcca
     5521 ctatataata aacgtgttaa gagaactaag aaattcaagg ctcatgatga aaagaatata
     5581 tgtaacatcg gagatagagt taaaataatg gaaactagac cattatctaa agataagaga
     5641 ttcagactag ttgaagttgt tgagaaagtt aagtagtttt tgaagaagga gggattacga
     5701 tatgatacaa caagaatcac gtctaagagt tgctgataac tcaggagcta aagaactttt
     5761 atgtatacgt gttctaggcg gaagtaaaag aagatatggt aacataggcg acgttatagt
     5821 tgctactgtt aaaagtgcaa cacctggtgg agttgtaaaa aaaggtaagg ttgttaaagc
     5881 tgttatagta agaagcaaac aaggcgtaag acgtaatgac ggaagctata tatcttttga
     5941 tgaaaatgct gctgttataa taaaggacga taaaactcca gtaggaactc gtatattcgg
     6001 gcctgttgct agagagttaa gagacaatga attcatgaaa atagtttctc ttgctccaga
     6061 agtactataa ttaaggaggt gcaataggac atgatgcgtg ttaaaaaagg tgacactgtt
     6121 gtagttatag caggtaaaga taaaggtaaa aaaggttcag ttttaaaggt atatcctaaa
     6181 actagcaaag tgttagttga aggtgtaaat gtaataacta aacatcaaaa accaagtgct
     6241 atgaaccaac aaggtggaat aataaataaa gaagccccaa tacacatatc taatgtaatg
     6301 ccatttgatc ctgaaacagg aaaaggcgtt agagtaagat atgaagtaaa agatgggaac
     6361 aaagtaagag tatcagcaaa gagcggaaaa gaattataat aaatattgct tgaaaggagg
     6421 gaccttaaat ggcttctaga ttacaagaaa aatacatgaa agaagttgct cctgctttaa
     6481 tggagaaatt tggatacaaa aacgtaatgg agatacctaa gttaaataaa atagttatta
     6541 acatgggtat aggtgacgct agagaaaatc caaaaggatt agaaaaaggc gttgaagaat
     6601 tagaaatgat atcaggacaa aagcctgtta taactaaagc tagaaaatct gttgctaact
     6661 tcaaattaag agaaggaatg ccaataggaa caaaagttac attaagagct gacaaaatgt
     6721 tctactttat ggacaaatta gtttcagttt ctttaccaag agttagagac tttagaggag
     6781 ttaaccctaa tgcttttgat ggtagaggaa attatgcttt aggagttaaa gaacaattaa
     6841 tattccctga aatagaatat gataaaatag ataaagtaag aggaatggat ataatatttg
     6901 ttactacagc aaaaactgac gaagaagctc gtgaattatt aaaattatta ggaatgccat
     6961 tttctaagta agcaaaggag ggattcccgt ggctagaaaa gcgatggttg ttaagcaaca
     7021 aagaaagcaa aagtacgcta ctagagaata cactagatgt actatatgcg gaagaccgca
     7081 ttcagttttg aaaaaatttg gtatatgccg tatatgcttt agagaattag cttataaagg
     7141 tcaaatacct ggtgttagaa aagcaagctg gtagaagctt gattagaatg gaaggagggc
     7201 aacaaaatga caatgacaga tccaattgca gatatgctta ctcgtataag aaatgctaat
     7261 gttgttaagc atgaaactgt agatgttcca gcttctaata tgaagaaaga attagctaga
     7321 atcttattag aagaaggttt cataagaggt tatgatgtta tagaagatgg aaaacaaggt
     7381 atcataagaa tacaattaaa gtacggacaa gaaggcgaaa gagttataac aggtcttaag
     7441 aaaatatcta agcctggaat gagagtttac gctgctaacc atgagatacc aaaagtatta
     7501 aacggattag gaatatcagt tatatctact tcaaaaggaa tattaactga caagcaagct
     7561 agaaaagaaa atgttggtgg agaagtaatc tgctacgttt ggtaattaat atgaacaatg
     7621 taaggaggtg cgaccatgtc aagaataggt gttaagccaa taataatacc agcaggtgtt
     7681 gaagttacta tagctgaagg aaatttagtt acagtaaaag gtccaaaagg aactttaact
     7741 aaacaattaa gtgctgagtt aaacataaaa aaagaagaaa atacaataat ggttgaaaga
     7801 ccaactgata ataaaaaaca tagatcttta cacggactaa ctagaacttt attagataat
     7861 atggttgtag gtgtaaatac tggtttcgaa aagaaattag aattaaaagg tgttggatat
     7921 agagctcaaa aacaaggaaa gaaattagtt atgaacttag gtttctctca tccagttgag
     7981 atggaagatc cagaaggaat aactgttgaa gctccaaacc aaacagagtt aatagtaaaa
     8041 ggtatagaca agcaattagt agggaattat gctgctaaga taagagcttg gagaaagcca
     8101 gagccataca aaggtaaagg tataaaatac gttgatgaag taatcagacg taaagaagga
     8161 aaaactggta aaaaataata ccaaaactta aacgctagaa aggagtgagc tagatgttaa
     8221 aaaaggctga taaaaatgct aatagacttc aaagacataa gagagttcgt agaaaaataa
     8281 gcggtacttc tcaaagacca agattatgtg tatttagaag tgctaacaat atatatgctc
     8341 aaataataga tgacacaaaa agagtaactc tagttgctgc atcttcttta gaagcagaag
     8401 ttaagagtgc tgtcaatcat acaggaaaca aggaagcagc taagaaagtt ggagaattag
     8461 ttgctaaaaa agctgttgaa aaaggaatca ctgaagttgt atttgacaga ggtggatact
     8521 tatatcatgg aagaattcaa gaattagctg aaggtgctag agaagctggt cttaagttct
     8581 aatacgaagg agggaaaaat acatgctacg tcgtaagccg atagatgcag gacaacttga
     8641 cttacaagaa aaagttgttg aagtaagacg tgttactaag gttgtaaaag gtggtagaaa
     8701 tttcagattt gcagcattag tagttgttgg agatgaaaac ggacacgttg gtataggtgc
     8761 tgggaaagca atggaagtac cagacgctat aaaaaaagca gttgaagatg ctaagaaaaa
     8821 tctaatagta gtgccaatag ttgggactac aattcctcac gaagtacgcg gacactttgg
     8881 tgctggaaat atattaataa tgcctgctgt agaaggtaca ggagtaatag ctgggggacc
     8941 tgctagagcc gtacttgagc tagctggact aaaagacgtt agagctaaat ctttagggtc
     9001 taacaatcca agaaatatgg taaatgctac aatagaagga cttaattctc taaaaacagt
     9061 tgaagatata gctaaactta gaggtaaaaa agttgaagaa cttctagggt aaggaggtag
     9121 tgtaaaatgg ctaaattaca aataaagtta gttagaagtg ttataggaac tactcctaac
     9181 caaaaaaaga atgttgaagc gttaggatta agaaaaagag aacaagttgt tgtaaaagaa
     9241 gacaatgctc aaacaagagg tatgataaat aaagtaagtc acttattaga agtaactgaa
     9301 atagctgaat aatttttata aagtagtgca aggaggtgca atccatgaag ttacatgagt
     9361 taaaacctgc tgaaggtgca gtaagagcta agagaagatt aggtagaggt actgcaactg
     9421 gacaaggtaa aactgcagga cgtggacaaa aaggtcaatg gtctcgttct ggtggtggag
     9481 taagagtagg atttgaaggt ggacaaatgc cactagctag aagacttcct aagagaggtt
     9541 tcaataacat atttaagaaa gtttacacag aagttaatgt tgaagtttta aacagatttg
     9601 aaaatggaac agaaataact gcagaattat taaaatctac taaaactata agcaaaatag
     9661 gtaaagacgg aattaaaatc ttaggtgaag gtaatttaga gaaagcttta actgttaaag
     9721 ctgctaaatt tacagcttca gctcaagaaa aaatagaaaa agctggtgga aaagcagagt
     9781 tagtataata acctgctaat ctcctagcca gtacaggcgg ggtgaattag cgtgctgtca
     9841 aaattaaaac aagcttggaa gattaaagca gtaagaaaaa aagtaatgta tacacttatg
     9901 atgatcgtga tattcagaat aggtactact ataccagttc caggcataga cactagtatt
     9961 atacaaaaga tggtaggcgg caatagtcta ctttctctgt ataatatgtt tactggtgga
    10021 gcatttagta acttttcact atttgcttta ggtataagtc catatatcac tgcatcaatc
    10081 ataatacaac ttctaacagt aggttttgaa agtttagcag aacttcaaaa atctggtgaa
    10141 gaaggaaaga aaaaaatcaa taagtacact aaatatacag cactagctct agcagttgta
    10201 caagctttgg gaattacatt aggaattgta agaagtgctt taatatcaaa tagtgtgttt
    10261 tttatcacaa ctgttgtaat aacattagtt tcagcaagta tgttagtaat gtggattggg
    10321 gacaaaatta ctgaaaaagg aatcggtaat ggtagttcag taataatatt tgcaggtata
    10381 atatcaagaa tacctacaga tgttattaaa atatcgcaac aagttaaatc tggcgaagtt
    10441 gcaccttggg ttatagtgat tctagctgta gttatattac ttacagtaac aggagttaca
    10501 tttatacaag aagcaactag aaagatacct gtacaatatg ctaaaagagt tgttggaaga
    10561 aaaatgtatg gaggacaaag ttctcatata ccaatgaaag ttaaccagtc aggagttatg
    10621 cctataattt ttgctagttc acttttagct ttccctcaaa caatagctat gtttatgggt
    10681 ccaaatgctc aggcttttgt tcaaaaatac ttaagtatgg caacagaaca aggattttgg
    10741 acatatagat caattgagat tctacttata attttcttct catattttta tacaactgta
    10801 tcatttaata cagaagacat atctaaaaat atgaaaaata atggtggatt tataccaggt
    10861 ataagaccag gtgagcctac tatggattat ttaaatagaa ttttaactag attaacttta
    10921 gctggagcta ctttcttagc aataattgct atggtgccag ctcttacaac acattatatg
    10981 aaagtaaata tgagtctagc tgggacttca ttgctaatcg ttgttggagt tgctttggag
    11041 cttaagagac agttagagtc aaacttagtt atgagaagct atcaaggttt cttaaaataa
    11101 aatggagatg gataatatga gaataatatt acttggacct ccaggtgctg gtaaaggtac
    11161 tcaggcggca ggaatagtag aaaaatacaa tatacctcat atatcaacag gagatatatt
    11221 cagaaagaat ataaaagagg gaacagaact tggaaaaaaa gctaaagaat acatggacca
    11281 aggtttatta gtaccagatg agttaactgt aggtttagtt actgatagaa tatctcaaga
    11341 agattgtaaa aatggattta tgttagatgg atttccaaga aatgtagcac aaggagaaca
    11401 tttagatatc ttcttaaaaa atgctggtat atcactagat aaagttgtca atattgaagt
    11461 tgataagagt atattagtgt ctagagcagt tggtagaaga atatgtaagt cttgtggagc
    11521 tacttaccat gttgagttta atcctcctaa agtagaaggt gtatgtgatg tatgccaagg
    11581 agaattatat caaagagctg atgataatga agaaactgta tctaagagaa tacaagttta
    11641 tctagatgaa actaagcctt tagtagatta ttatagcaaa caaggtataa tagcagatat
    11701 aaaaggtgat caagcaatag ataaagtatt tgaagatatt gtcgcagcct taggaagtgg
    11761 aaaataaatg attatcttga aatcaaaaaa agaaatagaa cttttaagag aagcaggtaa
    11821 aatagttgct gacactcatg aagttttaag aaaagctatt tctccgggaa tatctacttt
    11881 agaattagat aaaatagctg aagagaatat aagaaaatac aatgcagaac cttcttttaa
    11941 aggatatgga ggttttccag gaagtatatg tgcttctatc aatagagagg tagtacatgg
    12001 tatcccagga gaaactatat tacaagaagg tgacattgta agtttggata taggagccta
    12061 ttataaagga tatcatggtg attctgcgaa aactcacgga gtaggcatga tatctgaaga
    12121 agataggaaa ttgatagaag taactagaga aagcttctat gaaggaataa aatttgctaa
    12181 attaggatat agactttcag atatctcaca cgcagtacaa acacacgttg agaaacatgg
    12241 tttctcggta gttagagatt tagtgggtca tggagttgga gcaaatcttc atgaagaccc
    12301 acaagtacct aattatggac tcccaggaaa aggaccaaga cttagagaag gaatggttat
    12361 tgctatagag ccaatggtta atgcaggtcg ttatcatgta aagactctat cagatgggtg
    12421 gacgactgtt acaatagatg gaaaaaaatc agctcattat gagcatacga tagcaattac
    12481 tgaacatgaa cctttgatat tgacaaagtt gtaatttaaa aagtaggtga aaaaagtgct
    12541 atcagataat ttaagtatag gtcaagttgt taaagtttca ttaggacgag ataaaggaaa
    12601 tttattcttt gtagtcaaaa taattaataa tgaatatgta ttaatagctg atggaaaaaa
    12661 gagaaaactt gacaaaccta agttaaagaa agtgaagcac ttaaaaaaat ataattttat
    12721 taatgatgaa gttagaaaaa gagtagtatc tggacaagag attacagatt cttttttaag
    12781 agctgaactt actaagttaa attagataat ttaacttatt gaaatggagg gctggttagt
    12841 taatggccaa aaaagatgtt atagaattag aaggtacagt ttcagaagct ttacctaatg
    12901 ctatgttcaa agttaaacta gaaaatggac atgagatatt atgccacatt tctggaaagc
    12961 taagaatgaa cttcataaga attcttgaag gtgacaaggt gaatgttgaa ctttctccat
    13021 atgaccttac aagaggaaga attacttggc gtaagaagta gactatatta atatttagtc
    13081 taaggaggga ttaataatga aggttagacc atcagtaaaa ccaatatgtg aaaaatgtaa
    13141 agtaataaaa agaaaaggaa aagtaatggt tatctgtgaa aatccaaagc ataagcaaaa
    13201 gcaaggataa gaaattatta ctagcatttt gttaaatttt atagtataat actatattgt
    13261 gatgttaaca aaagaacgtt aaaatcgttg aacaatctgg cgtaggattg gcatatgatg
    13321 tgaagtttta aacactaaaa actatgtgta ggaggtgcga tcatggcaag aatagctggg
    13381 gtagatttac ctagagaaaa aagagcggag ataggcttaa cttatatata tggtataggt
    13441 aaagcaactg ctaacgaaat attagctaag gctgagataa atccagatac tagaataaaa
    13501 gatttatcag aagatcaagt taatgagtta agaaaagtta tagatgacga tttcttagtt
    13561 gaaggtgact taagaagaga aattgcttta aacataaaga gattaagaga tataaaatgt
    13621 tatagaggaa taagacacgc taaaggtctt ccattaagag gacaaagaac taagactaat
    13681 gctagaacta gaaaaggtcc tagaaaaaca gtatctcgta aaaagaaaaa ataaataaat
    13741 aataactaga tgaaggaggg aaaaggaaaa tggctaaacc aaaaaagaaa gttacacgta
    13801 ttagaagaag agaacgtaaa aatatagaac gtggtcatgc tcatatacaa tcaactttca
    13861 ataatacaat aataacttta actgacgttc acggaaatgc tatatcttgg gcaagttctg
    13921 gacaattagg attcaaagga tcaagaaaat caactccatt tgcatctcaa atggctgctg
    13981 aaacagctgc aaaagctgcg atggaacacg gactaaaaag tgttgaggta ttcgtaaagg
    14041 ggccaggttc aggaagagaa gctgcaataa gagctttaca agcaactgga ctagaagtaa
    14101 ctatgataaa agacgttact ccaatcccac ataacggatg cagaccacca aagagaagaa
    14161 gagtgtaatt aataagagta caataggagg tgtagataaa tggcaagata tacaggtgca
    14221 tcatgtagac aatgccgtag agagggaatg aaattattcc ttaaaggtga tagatgttat
    14281 acagacaaat gtgctatagt aaaaagaaac tatgctccag gtcaacatgg ccaaggaaga
    14341 aagaaagttt ctaactatgg attacaatta agagaaaaac aaaaagttaa aagaatatat
    14401 ggagttttag agactcaatt tagaaattta tatgaacgtg ctgaaaatat gcctggtaaa
    14461 gcaggtgaga acttattaag tttattagag agaagattag ataatgtagt ttacagaatg
    14521 ggactagcat cttctagaaa agaagctaga caattagtga ctcatggtca tttcacttta
    14581 aatggaaata aagtagacat accttcatta atagttaagg ttggagatgt tatagaagtt
    14641 aaagagaaat caagatcttc tgcaaaattc aaaaatttag tagaagttaa ctcaagaata
    14701 gctcctaagt ggttagaagc taatgtagaa ggaatgacag caaaagtagt tggtgttcca
    14761 acaagagaag atatagatct tgagatagca gagcacttaa tcatagaact ttactctaaa
    14821 taataagcac acttttaaaa attattttaa aattttgttt accctcagtg gattactgaa
    14881 ttttaaggag ggttttgtcc atgatagaaa tagaaaagcc aaaagtagat atagttgagc
    14941 ttagcgaaga ctatagatat ggtaagtttg ttatagagcc tctagaaaga ggatatggaa
    15001 taactatagg taacgcatta agaagaatat tattatcatc attaccaggt gtagcagtga
    15061 atgctataaa aatagatgga gttcttcatg aattttcaac aatacctggt gttaaagaag
    15121 atgttactga gataatatta actttaaaag agctttcagc aactatagat ggtgaaggaa
    15181 gtagaacact taaaatagaa gctcaaggac catgctctat cacaggtgca gatataatct
    15241 gtcctccaga tgttgaaata ttaagtaaag atttagcaat agctacatta gatgataatg
    15301 ctaaacttaa tatggagata tttgtagata aaggtagagg ttatgtttct gctgaagaaa
    15361 ataaaacaga gaatgttcca ataggtgttt tacctgtgga ttcaatatat actcctgttg
    15421 agaaggttag ttatcatgtg gaaaacacaa gagttggtca aaaaacagat tatgataaat
    15481 tagtattaga agtttggact aatggtagta taaatcctca agagggaata tcattagctg
    15541 caaaggtatt agttgagcat ttaaacttat ttatagactt aactgaacat gtaagtagtg
    15601 ttgaaatcat ggtagaaaaa gaagaagatc aaaaagaaaa agttcttgaa atgactatag
    15661 aagaattaga tttatcagtt agatcatata actgtttaaa gagagcggga attaatacag
    15721 ttgaagaatt agctaataaa tctgaggatg atatgatgaa ggttagaaac ctaggtaaga
    15781 agtcattaga agaggtaata caaaaactag aagaacttgg attgggatta aaaccaagtg
    15841 aagaatagcg agcaaaggag ggataagaat ggctaagtac cgtaaattag gacgtgaaac
    15901 agctcacaga aaccttatgt taagaaactt agtaacttgc ttactaagaa gtggaagaat
    15961 agaaactaca gtgactagag cgaaagaaac tcgtagaatg gctgaaaaga tgataactct
    16021 tgctaagaga ggagatcttc atgctagaag acaagtttta gcttatgtta tggatgaaac
    16081 agtagttaat aacttattca cagatttagc tccaaaatat gctgagagaa atggtggata
    16141 cactagaata ataaaaatag ggccaagaaa aggcgatgct gctgaaatgg cttttataga
    16201 attagtatag taaggaaagg attaggcttg atggcttaat ctttttttta tttttttgac
    16261 taaggtatga tataataatg tgtaaaatga tttttataag ttattgctta ctaaaaggag
    16321 tatgagttaa tggataatat agtaaaggta aataatattt cgtttgagta tattacagat
    16381 gaagcaaaac ttaaagcaat agataattta agcctagatg ttaaaaaagg agaatttgtt
    16441 gcgataatag gacataatgg ttctggtaag tctactttat ctaaaaactt aaatgctatt
    16501 cttatgccta ctgaaggaaa tattcttatt gatgatatgg atactaaaga agaagaaaga
    16561 ttatgggata taagacaaac tgcaggcatg gtatttcaaa atccagataa tcaaatagtt
    16621 gctactatag tagaagaaga cgttgcattt ggacctgaga acttaggtat agaaccaaaa
    16681 gaaataagac gaattgtaga ggagtcttta aaaagtgtag gtatgtatga tttaagagat
    16741 agacagcctc atttgttatc aggaggtcaa aagcaaagag ttgcaatagc aggaattatt
    16801 gctatgaggc ctaaatgtat aatatttgat gaagcaacag caatgttaga tccatctgga
    16861 agaaaagaag ttatgaaaac aataaaaaga cttaataagg aagaaaatat aactgttata
    16921 catataacgc actttatgga agaagcagta gaagctgata gagttgtagt tatggaaaaa
    16981 ggaaagaaaa tcttagaggg aactcctaga gaagtattca gtaaaataaa gatgttaaag
    17041 gaaatcggtt tagatgtacc ttgtatgaca gagttatcta gtttattaat agaagaaggt
    17101 ataaatatta gtagtgatat attaactgtg gatgagatgg tgatggaatt atgtcaatta
    17161 tagtaaagaa tttaacacat atatataatg aagggatgcc ttttgcaagt aaggcacttg
    17221 atgatgtttc ttttgagatt aaagatagag attttgttgg tcttataggt catacaggct
    17281 caggaaaatc tacattaata caacatttaa atggattact aaagccttcc tcaggagaaa
    17341 tatttataaa tgattttaat ataacagata aaaacttgaa tttaactgag attagaaaaa
    17401 gagtaggggt tgtatttcaa tatccagaat accaattgtt tgaagaaacg attgataaag
    17461 atatagcttt tggaccctct aatttaggct tagaggagtc tgagatacat aacagggtaa
    17521 aagcatcaat ggaagctgta ggacttgatt atgagggatt taaagacaaa tctccttttg
    17581 aattatctgg gggacaaaag cgtagagtag caattgctgg agttatagcc atgaacccag
    17641 aagttctcat attggatgaa ccaactgctg gtcttgaccc tggtggaaga gatgaaattt
    17701 ttaacttaat aaaagactta catgaaaaaa agaatatgac tataatacta tcatcacata
    17761 gtatggatga tatggcaaag ttagcaaaaa ctttaattgt tatgaatcat ggtagcgtag
    17821 aatttatggg aactcctaga gaagtattta aatcaaatgc tagtaaatta aaagatatag
    17881 gattagatat tccacaagtt ttagagcttg cattgaaatt gagagaaaaa ggctttgaca
    17941 tcagtgagga tatattgact ttagaagaag caaaacagga aatattaaaa gttgtgagag
    18001 gacgaggatt atgttaaaag atataactat agggcaatac tacccaacaa gttctgctat
    18061 tcataaatta gatccaagga taaagcttgt agcgacaatt gtatttatgg tatctatatt
    18121 tgtagtaaat aaattttggc cttatatagt agttttatta tgtttattag ctatgataaa
    18181 attggctaat ataccagtca aatatattgt taagggtgtt aaacctctta aatggattat
    18241 tttgtttaca tttcttataa atattttttt cttaccaggt gatgaaatat ggtcatttgg
    18301 atttttagct attacaaaac agggtctaag acaagcaatt tttatggcaa taagattaat
    18361 atttttagta gttggtacat cattgcttac tttaacaact tcaccaatag aattaactga
    18421 tggaatagag agattgttga atccatttaa gaaaattggt ttgccagttc atgaacttgc
    18481 aatgatgatg acaattgctt tacgttttat tcctacattg ttagatgaga cagacaaaat
    18541 aatgaaggct cagatgtcta gaggtgcaga ttttgaaagt aagaatctta taaatagagc
    18601 aaagaattta gtaccacttt tggtaccttt atttgtaagt gcatttagaa gagctgatga
    18661 attggctatg gccatggagg ccagatgtta cagaggtgga cataatagga ctaagatgag
    18721 agagtctgtt atatcaagaa gggattatat ggcatgtgta tttcaggttg tttatctggg
    18781 agcaattata gctactagat ttatagcaat ttaattaata agttatagat ataatgaggt
    18841 aaagtatgag aaatataaaa attaaaatcc aatacaatgg taagaattat tgtggatggc
    18901 aaaagcaacc tgattcttta gggatacaag gtacaattga aagggctata tatgatataa
    18961 caaaagaaga aaccagtctt atagggtctg gtagaactga ttcaggagtt catgctattg
    19021 gtcagattgc aaattttaaa attaattcag gtataagtat agaaagtata ccaatggcac
    19081 taaatgccaa gttgccaaaa gacatatcag ttatagaagc atgtgaagta aatgatgatt
    19141 ttcactccag atacagtgca aaaggtaaaa catataaata tttagtatat aatagcaagt
    19201 ttagaaatcc aatacttagt gagatatcat atcaagtaaa atatgaactt gattttgata
    19261 aaatgtgttc agaagcaaaa agtttattag gaacacatga ttttaaaggt tttatgagtt
    19321 ctggttcatc tgtaaaagat acagttagaa cgatatatga tattgatata agtaaaaaag
    19381 atgacttgat tacttttgag attagtggta atggtttttt atataacatg gtgaggatta
    19441 ttgttggaac acttgttgat atgggtcgtg gcagaattaa cgaaccattt ttagatataa
    19501 tacaatcaaa aactaggtca agatgtggac atacagctcc agcacaagga ttatttctca
    19561 aaaaagttca ttattaactt gacacaccag gctacatgta ttaaaatata tgagaatgtg
    19621 ttaataagtc cacttgcccc ggacttgaca taaacggtaa aaaaatttta tgaaaagtag
    19681 ttaaggaggg acagttatga aaagttatat agctaagcca gctgatgtac aaagaaaatg
    19741 gtacttagtt gatgctgaag gaaaaacatt aggtcgttta gcaacagaaa ttgcgacagt
    19801 attgagaggt aaacataaac caacatttac tcctcacgtt gatggtggag attttgttgt
    19861 tgtagtaaat gcagaaaaaa tagttttaag tggtaagaaa ttagatcaaa aatattacag
    19921 ataccatact ggttatgtag gtggattaaa agaaatatct tatagagata tgatggataa
    19981 gaaaccagaa gaagttatat cacatgctgt aagcggtatg ttacctaaaa ataaattaag
    20041 aagcagaatg atgactagat taagagtatt tgcaggtgct gagcacactc atgcagctca
    20101 aaatccagaa gttttaaact ttaaataaga ttaataggtg aaaggaggag tttataatgg
    20161 ctaacgttca atattatgga actggaagaa gaaaaagttc tgttgctaga gtaagactag
    20221 ttgcaggtga aggaaatata ttagtaaatg gaagagcatt agaaaattat tttaattatg
    20281 agacattaat aagagatgtt aaacaaccat tagttttaac tggtaatgaa aataaatatg
    20341 atgttatagt aaaagttgaa ggtggaggat tcactggaca agctggagct ataagacatg
    20401 gaatatctag agctttatta aaagctgatt tagatttaag acctgcttta aagaaagaag
    20461 gtttcttaac tagagatgca agaatgaagg aaagaaagaa atacggatta aaagcagcaa
    20521 gaagagctcc acaattctca aaaagataat tacttatttt tttggaaaag caaaatcctt
    20581 tatttactgt tattcagaaa gtattggtat tttaaaaatg ttgggttaag ttaattattg
    20641 atatataata aaataataag atatcttatt aggatgtttt tcattaagaa gaacatcctt
    20701 tttattttga
//
LOCUS       DAYAOO010000072        20517 bp    DNA     linear   BCT 12-OCT-2024
DEFINITION  TPA_asm: Clostridioides difficile isolate ST8-SSI-h139-18
            SAMN40601845-rid21577343.denovo.072, whole genome shotgun sequence.
ACCESSION   DAYAOO010000072 DAYAOO010000000
VERSION     DAYAOO010000072.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN40601845
            Sequence Read Archive: SRR28438827
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 20517)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 20517)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-MAY-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-MAY-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002157583.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002157583.1
            Genome Coverage       :: 163x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/11/2024 16:19:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 4,038
            CDSs (total)                      :: 3,963
            Genes (coding)                    :: 3,930
            CDSs (with protein)               :: 3,930
            Genes (RNA)                       :: 75
            rRNAs                             :: 6, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 60
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 33
            CDSs (without protein)            :: 33
            Pseudo Genes (ambiguous residues) :: 0 of 33
            Pseudo Genes (frameshifted)       :: 7 of 33
            Pseudo Genes (incomplete)         :: 25 of 33
            Pseudo Genes (internal stop)      :: 11 of 33
            Pseudo Genes (multiple problems)  :: 8 of 33
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..20517
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN40601845-rid21577343.denovo.072"
                     /isolate="ST8-SSI-h139-18"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Denmark"
                     /collection_date="2018"
                     /collected_by="Statens Serum Institute"
     gene            35..2983
                     /locus_tag="ACGI5H_002868"
     CDS             35..2983
                     /locus_tag="ACGI5H_002868"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009887817.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0008134 - transcription factor binding
                     [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sigma 54-interacting transcriptional regulator"
                     /protein_id="HFG9698565.1"
                     /translation="MRQRIKNLIENEDKKNPLTDEAISSRLNIRREDVTFLRNELKIE
                     DSRQRRKVVLIKAIKDILKEEKTINKNDITRRLNSIGFTVSRFTVIQYLKEIQDSGDL
                     KLDKESDDKKEEIINNRENKDIAFDKLIGSSGSLSTIIKLAKAAILYPPHGLHTIIMG
                     PTGVGKSELAECMYKFAVESSRFPKNAPFIVFNAADYSENPQLLLSQLFGHVKGAFTG
                     ADENKEGLVSKADGGILFIDEIHRLPHEGQEILFQLIDKGMVRKLGETRLTHKIDVMI
                     ISATSEPIDSHLLNTFKRRIPVTIEIPELVARPLNERFDIINNFFLIEAQRMGANIHI
                     KSDVLKALMLYDCIGNVGQLRSDIQVACARGLLNQLTNKLKEVNISISDVPGYVKQGL
                     IKIRNCRGKIENYVDGDLIIDSNLQGEIEKKNEDIYTFPDEIYKLTERRHIDLLEQGL
                     DFDVINRIIGGELESCIQKYIKQVKKVSISNNLPDISPIVGKYIVELTYEVIKIASQY
                     LSSLEPNLHLCLAVHLKAAFERLKEGKVISNAHLKEIIGNYPLEYSVAEKVAQYLKER
                     YNINLPKEEIGIIAIYFKMSSRRDMSEQKKIGVLLMAHGRVASSVCEVTNKLLGINHA
                     RYLDMPFEKKPEEMIEEATTIIKDIDEGRGVIILVDMGSLSYFGDIISGKTGINIRTI
                     SRFDTLLSIEVIRRAVLPDLTIDEIVDEVKGIEPQVKEKVSKCNNTKVDFRKPIILTL
                     CITGLGGACKIKKILEENIKSITEKVDIEPIGMIEYPSLDLEIKQISNDKNVIAIVGT
                     IDPQIANIPFFSLVDINDKAKLNQINNLIDTNQIGETNKKYELSDLIHKEDIFVDLQV
                     KSKEEVLKYMSKKLREKGYVTKNFYKKVVERDNLFPTELSDEIAIPHTDGIDVIRPAI
                     SIAILKKPIVWSKSKVKIILLLAVDQKCFNPLSTLLSFIETDEFKKIKNIKDRDFIRE
                     MILDGVNENN"
     gene            2961..3425
                     /locus_tag="ACGI5H_002869"
     CDS             2961..3425
                     /locus_tag="ACGI5H_002869"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892531.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:1902495 - transmembrane transporter
                     complex [Evidence IEA];
                     GO_function: GO:0016301 - kinase activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA];
                     GO_process: GO:0016310 - phosphorylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HFG9698566.1"
                     /translation="MESMKIISSNLIFKNIEVSNNEDALKFLGQRLFDEQYVKESYIQ
                     AVVAREKKYATGLPTEIYGVAIPHTDIVHVNEPGIAIGILNKPVKFIMMGTDDTEIDV
                     KVVFMLAVKEPQEQLQLLEKLMTIFQDKNILNNIVDLSEESVSDLLNSKLKN"
     gene            3538..3840
                     /locus_tag="ACGI5H_002870"
     CDS             3538..3840
                     /locus_tag="ACGI5H_002870"
                     /EC_number="2.7.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004453958.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HFG9698567.1"
                     /translation="MGVTNVAKKILVACGTGVCTSTIAINKLKKALQDIGKLDMVNIT
                     QCKVVEVASKAPDYDLIICTTQVSSSIKTPVINGLPFLTGVGMDKLINDVLEELEL"
     gene            3917..5266
                     /locus_tag="ACGI5H_002871"
     CDS             3917..5266
                     /locus_tag="ACGI5H_002871"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009887822.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit IIC"
                     /protein_id="HFG9698568.1"
                     /translation="MEILNFIVGLGAQVMMPIIICIFGLILGTKLGKSLRAGLTVGVG
                     FIGLNTIIALLTDNLGPATQQMVKNLGLSLSIIDVGWPAASAIAFASTVGALIIPIGL
                     VVNIVMLITNTTQTVDVDIWDYWHFAFTGALVAGATQSVMWGVFAAVANMVIVLVMAD
                     LTAPGIEEYLGMPGISLPHGFTQAFVPIAIVVNKLLDLIPGINKIEINADTLQKKFGL
                     FGEPLIMGSVIGVIIGIAAKYDIKGILQLGVTMGAVLILIPKMAALLMEGLLPVSEAA
                     QEFIEKRFKNRGKIYIGLDSAVGIGHPVTLSVALVLVPLTILIAAILPGNKVLPFADL
                     AVIPFALVLIVPITKGNVFRTLIIGIIIITSGLLIATNLAPLFTQMALNASFKMPEGA
                     TMISSICDGANPLSWVFVKVMNYKVIGGVVFGVIALGMAIYNRNRIINENKKLSIEE"
     gene            5301..5774
                     /locus_tag="ACGI5H_002872"
     CDS             5301..5774
                     /locus_tag="ACGI5H_002872"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009901560.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9698569.1"
                     /translation="MKKYKYDSKRYLLSVTIPGFFMILILIYALFNNYTNFNLNIYSL
                     LIIVCTYGIFNTFISSSNPKKIIIDSKCIHFTSFMTTHKYEIKDIEKIRIREFYNKKI
                     YLKINDGKLFKGRYWIRTNMFNNSIALYSYFIELEECLYPDSLKFRNKKFENKNI"
     gene            5946..6596
                     /locus_tag="ACGI5H_002873"
     CDS             5946..6596
                     /locus_tag="ACGI5H_002873"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421209.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class II aldolase/adducin family protein"
                     /protein_id="HFG9698570.1"
                     /translation="MLLEKLRKEVLQASLDLLNYNLVTLTGGNVSGRDEQTGYIAITP
                     SGMDYRNLTPSDIVIVDVDGNIIDGKWKASVDLSDHLYIYKHREDINSIIHTHSTYSS
                     CFAILNEPIECASTTLANEVGGSVPVAKFSPPTSKKMGKCVIEAIGDKRACLLANHGV
                     IAVGPSVGHALTAAVMLEDSAKVYYLAKSIGTPVLLPDEEIQRARDVFFNVYGQDK"
     gene            6770..7702
                     /locus_tag="ACGI5H_002874"
     CDS             6770..7702
                     /locus_tag="ACGI5H_002874"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421208.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="biotin/lipoate A/B protein ligase family
                     protein"
                     /protein_id="HFG9698571.1"
                     /translation="MYYLLNKSTNPYFNLALEEYLFLNDKYNDDIIIIWRNEESIFIG
                     KNQNPYQEVYHDVIEKGEIPILRRISGGGTVYHDLGNINMSFIQKDRQLHEIDFLEHT
                     KFMQKMLSTLGLDVSITERKDLFLNGKKISGSAQSIKRKNSLYHGTLLYDSDLNKLTK
                     YLNSNKATESNATKSVSSKVTNIKFLLEKDINYFLDYCVEYLKSNIKNIKELELDEED
                     IKSVYNIGEDKYKKIEWTYGKTPKFQVVLPFNNESKINIHVNRWKVSKFFISYDDNVI
                     NMDKLLDLNFFKEEIKESILENYPHYIDLINLIF"
     gene            7976..8689
                     /gene="ispD"
                     /locus_tag="ACGI5H_002875"
     CDS             7976..8689
                     /gene="ispD"
                     /locus_tag="ACGI5H_002875"
                     /EC_number="2.7.7.60"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009904750.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0050518 - 2-C-methyl-D-erythritol
                     4-phosphate cytidylyltransferase activity [Evidence IEA];
                     GO_process: GO:0008299 - isoprenoid biosynthetic process
                     [Evidence IEA];
                     GO_process: GO:0019288 - isopentenyl diphosphate
                     biosynthetic process, methylerythritol 4-phosphate pathway
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="2-C-methyl-D-erythritol 4-phosphate
                     cytidylyltransferase"
                     /protein_id="HFG9698572.1"
                     /translation="MYSVIIVAAGSGRRMNLDINKQFIKLREKEIIAHTIQVFYENIN
                     IDEIVVCIKKEEEDFFKENIINKYNFKNIKIAYGGKERQDSIYNGLKKLDKNCDIVLI
                     HDGARPFVDHRIINESIKVAKEKKAVVVGVPVSDTIKIVSDGTVQETPERNLLWAAQT
                     PQTFEYNLIIDAYEQAYKNNYYGTDDSMLVENIGQSVTMVMGSYENIKITSPEDLNIA
                     EQILNMEKRDEVNSRRRII"
     gene            8686..9171
                     /gene="ispF"
                     /locus_tag="ACGI5H_002876"
     CDS             8686..9171
                     /gene="ispF"
                     /locus_tag="ACGI5H_002876"
                     /EC_number="4.6.1.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009887828.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008685 - 2-C-methyl-D-erythritol
                     2,4-cyclodiphosphate synthase activity [Evidence IEA];
                     GO_process: GO:0019288 - isopentenyl diphosphate
                     biosynthetic process, methylerythritol 4-phosphate pathway
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="2-C-methyl-D-erythritol 2,4-cyclodiphosphate
                     synthase"
                     /protein_id="HFG9698573.1"
                     /translation="MRIGLGYDVHKLTEDRKLIIGGVEIPHDKGLLGHSDADVLIHAI
                     MDSILGALALGDIGKHFPDTDEEYKGADSMKLLEHVYNLITSKGYKIGNIDSTIIAQS
                     PKMAPYIESMRSNISKVLNTDIDNINIKATTEEGLGFTGAKQGIASQSICLLLLTSQN
                     N"
     misc_binding    9266..9474
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            9538..11253
                     /locus_tag="ACGI5H_002877"
     CDS             9538..11253
                     /locus_tag="ACGI5H_002877"
                     /EC_number="6.1.1.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435583.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0002161 - aminoacyl-tRNA editing activity
                     [Evidence IEA];
                     GO_function: GO:0004812 - aminoacyl-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0004827 - proline-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006418 - tRNA aminoacylation for protein
                     translation [Evidence IEA];
                     GO_process: GO:0006433 - prolyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="proline--tRNA ligase"
                     /protein_id="HFG9698574.1"
                     /translation="MKMSKMFMPTLKEIPADAEITSHQLMVRSGMIKKMTSGVYNQLP
                     MGLRVFKKIEQIIREELNKKDCQEILCAALLPSELWKESGRWTAMGEEMFRLKDRTER
                     EYCLGPTHEEAFTDIIRQEITSYKQLPLNLYQIQVKYRDERRPRFGVMRTKTFTMKDA
                     YSFDVDDKGLDKSYQDMFDAYVSIFNRCGLENSPVQADSGAIGGSTSAEFMVKSEVGE
                     DEVVFCSGCDYAANVERAESCNLASQKEEMKELEEVHTPGAATIKELEEFLKTSPDKF
                     AKTLVYEADGKTVVVVVRGDREVNEIKVSNAIGSVIEFALATDDVVRKVTNAEVGFAG
                     PIGINADYVFIDKEIVEQRNIVVGANKTEYHIKNANYGRDFEGIVGDFRNVQEGDKCI
                     VCGKPLEIARGVEVGHIFKLGTKYSESMNANFIDKDGKSKPIVMGCYGIGVERTAAAI
                     IEQHNDEKGIIWPLSVAPYHVVIVPANMKNEEQISIAENIYNDLQAMGVEVLLDDRDE
                     RIGVKFNDSELIGIPMRITVGKNINEGKVEFKLRHKEDKEIIDIEEINEKVKAEFIRN
                     NVRLG"
     gene            11375..12820
                     /gene="proS"
                     /locus_tag="ACGI5H_002878"
     CDS             11375..12820
                     /gene="proS"
                     /locus_tag="ACGI5H_002878"
                     /EC_number="6.1.1.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895182.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0004827 - proline-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006433 - prolyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="proline--tRNA ligase"
                     /protein_id="HFG9698575.1"
                     /translation="MAKNEKQFVEEITKMEDDFPQWYTDVITKTDLVDYAPVKGFMVV
                     KPYGYALWEKMQEFMDKKFKETGHKNCYFPLLIPESLLNKEAEHVEGFAPEVAWVTHG
                     GNKKLEERLCVRPTSETIICTMYAKWLKSYRELPYLYNQWCSVVRWEKSTRPFLRTSE
                     FLWQEGHTLHETAEEAQEETIQQLEVYKALCEELLAMPVVAGQKSESEKFAGGERTYT
                     IEAMMHDGKALQSGTSHFLGQHFTKAFDITFADREGNLANPYHTSWGASTRLIGGLIM
                     THSDNRGLVLPPRVAPIQVVIVPIAAKKGNVMETVDKIYADLKAKGVAVEVDDRDNYT
                     TGWKFNEWEMKGVPVRVEIGPKDIENNQAMVFRRDTLEKDSMPLEGLADAICDLFDVI
                     HNDMFEKARKHREDNTSIVENMDEFRKALEEKPGFIKTMWCGDAECEAKIKEETGATI
                     RCLPFEQENLGHKCVYCGKEADSMVVMAKAY"
     gene            13258..14739
                     /gene="gltX"
                     /locus_tag="ACGI5H_002879"
     CDS             13258..14739
                     /gene="gltX"
                     /locus_tag="ACGI5H_002879"
                     /EC_number="6.1.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892542.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0004818 - glutamate-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006424 - glutamyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate--tRNA ligase"
                     /protein_id="HFG9698576.1"
                     /translation="MNVRVRFAPSPTGFVHIGSLRTALYNYLFAKKMGGEYILRVEDT
                     DQSRLVEGAIENMLNAMKWAGVNHSEGVILDDSGKVVQKGEYGPYIQSQRLDIYQEYI
                     KQLLDSGKAYYCFCTKERLDEVRDAQRAAGETAKYDGHCKNLSKEEVEANIKAGIPYV
                     IRLRLPENHTIKFTDLVRGDMEFNTNDLDDQVLMKTDGFPTYHFAVVVDDYLMKITHV
                     IRGEEWVSSTPKHVYLYEAFGWEAPVFVHLPNILNKEKKKLSKRQGDVAVEDFKKKGY
                     LPEGLVNYVALVGWSPEDNQELFTMEELEKAFSVERVSKSGGVFDTEKLNWVNQHYIK
                     DGDDAYLTDLAIPFLIEDGFITEEEATNKYDFLKSMISVLKEKLQYVKEVTEHASIFF
                     GDKIEVETEEGREFLRLEHIPTLIDALREKIEKTEVLNAEFVQAMLKEIQKEYKIKGK
                     NLFMGSRIILTGQMHGPDLPKVMEVLGKETCLNRIAYVKNNIL"
     gene            14960..15115
                     /locus_tag="ACGI5H_002880"
     CDS             14960..15115
                     /locus_tag="ACGI5H_002880"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9698577.1"
                     /translation="MYSNIDDVKKELKELCLEYVTILEKLKDEKMITEETFEKCSSQK
                     KIFLEEQ"
     gene            15260..16657
                     /gene="cysS"
                     /locus_tag="ACGI5H_002881"
     CDS             15260..16657
                     /gene="cysS"
                     /locus_tag="ACGI5H_002881"
                     /EC_number="6.1.1.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895184.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0004817 - cysteine-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006423 - cysteinyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine--tRNA ligase"
                     /protein_id="HFG9698578.1"
                     /translation="MKVYNTLTRTKEEFVPLEEGKVKMYVCGPTVYNYIHIGNARPFI
                     IFDTLRRYLEYRGYDVTYVQNFTDVDDKIINRSHEEGISPEEVAAKYIKEYFVDCDGL
                     GIKRATVHPQVTDNIQQIIEFIKELEDKGYAYAVNGDVYFDTNKFEGYGKLSGQKQED
                     LEAGARIEVNDQKRHPMDFVLWKAKKEGEPGWDSPWGEGRPGWHIECSVMSKRYLGET
                     IDIHAGGQDLTFPHHENEIAQSEARSGKTFSKYWMHNGYININDEKMSKSKGNFFTVR
                     DISKLYDLEIVRFFMLSAHYRNPVNFSDEMLNQAKAGLERLYNTKEKLEFTLSNLVES
                     PLTEKEVELVKELDDFRQKFIDAMDDDVNTADAVSVIFELAKLINSNVDENSSLEFAK
                     KCLDEFNELTGVLNIVNKKKDTVLDKDIEELIQKRTDAKKNKEFQLADDIRQQLLDMG
                     IVLEDTRQGVKWKRI"
     gene            16660..17055
                     /locus_tag="ACGI5H_002882"
     CDS             16660..17055
                     /locus_tag="ACGI5H_002882"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860630.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004525 - ribonuclease III activity
                     [Evidence IEA];
                     GO_process: GO:0006396 - RNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease III domain-containing protein"
                     /protein_id="HFG9698579.1"
                     /translation="MEKTELVTMSPLVLAYLGDTVYETYIREYLIRQNTQRKVNDLHK
                     LAIKYVKAKAQATIIHEVEIELTEEESKIYKRGRNQKSNTSPKNADIIDYKHATGFEA
                     LVGYLYLNNEIERLQYIINKGIKIIERDM"
     gene            17161..17919
                     /gene="thyX"
                     /locus_tag="ACGI5H_002883"
     CDS             17161..17919
                     /gene="thyX"
                     /locus_tag="ACGI5H_002883"
                     /EC_number="2.1.1.148"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421197.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0050660 - flavin adenine dinucleotide
                     binding [Evidence IEA];
                     GO_function: GO:0050797 - thymidylate synthase (FAD)
                     activity [Evidence IEA];
                     GO_process: GO:0006231 - dTMP biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-dependent thymidylate synthase"
                     /protein_id="HFG9698580.1"
                     /translation="MKVKLISHTPEPEKVIAMAAKLCYSPVGTDEIEKDLTDESIEKF
                     LNMLLSIGHGSILEHASFTFSIEGISRACSHQIVRHRIASFSQQSQRYVKLEQFEYII
                     PPEIEKIEKAKELFIDSMKKDQENYDKLVEILFENHYNDLIKNGKNEKTAKRQAEKKA
                     IEDARYVFPNACETKMVFTINARSLFNFFEHRCCERAQWEIRNLAVEMLREVKKVAPI
                     LFKKTGPSCVNGSCPEGTMTCGDIVQVREKFKAL"
     gene            17932..18669
                     /gene="rlmB"
                     /locus_tag="ACGI5H_002884"
     CDS             17932..18669
                     /gene="rlmB"
                     /locus_tag="ACGI5H_002884"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009887855.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008173 - RNA methyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0006396 - RNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA
                     (guanosine(2251)-2'-O)-methyltransferase RlmB"
                     /protein_id="HFG9698581.1"
                     /translation="MASIEGRNPVIEAIKSDREIDKILIANSAKEGSIKKIIGMAKDK
                     NIIIQYVDKHKLDEVSTSHSHQGVIAYASEYKYYELDELIDLAKNKDEDPFFIILDEI
                     TDPHNLGSIIRTADAVGAHGVIIPKRRSVHITPVVAKASAGAVEYMPVCKVTNIVNTI
                     KRLKEEGLWIAAADMDGETFYKQNLTGPLGVVIGSEGFGISRLVKQNCDFIVKMPMIG
                     NVTSLNASVAGGILLYEIFRQRLDKSK"
     gene            18672..19199
                     /locus_tag="ACGI5H_002885"
     CDS             18672..19199
                     /locus_tag="ACGI5H_002885"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425496.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NYN domain-containing protein"
                     /protein_id="HFG9698582.1"
                     /translation="MKKNINHYLIIDGYNIINAWDNLKELAKEDLEDSREKLIDDIIE
                     FSEFMGYKTIIVFDAYNVKNSREKVEKRKHITIVYTREHQTADSYIEKFITSLSKYDD
                     VKVATNDYAEQQMILGKGATRMSARELKLELDRSKNKMKEKNIGLRKKIQRNWLEERL
                     DKETLSKLENIRRKR"
     gene            19264..19911
                     /gene="sigH"
                     /locus_tag="ACGI5H_002886"
     CDS             19264..19911
                     /gene="sigH"
                     /locus_tag="ACGI5H_002886"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892548.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA polymerase sporulation sigma factor SigH"
                     /protein_id="HFG9698583.1"
                     /translation="MLVAKEKSYELVDNCQQDEYNIVLRASEGDKIALEYIITKYRNF
                     VKAKAKSYFLIGADKEDIIQEGMIGLYKAVRDFDGSKTNSFKCFAEICITRQIITAIK
                     TATRQKHIPLNSYVSLNKPIYDEESDRTLLDIIATSIVTDPEELIISKEELKNIESKM
                     NELLSDLELEVLELYLNGKSYQFIADKLKRDVKSIDNALQRVKRKLEKHLENRND"
     gene            19985..>20517
                     /locus_tag="ACGI5H_002887"
     CDS             19985..>20517
                     /locus_tag="ACGI5H_002887"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009887863.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003924 - GTPase activity [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GTP-binding protein"
                     /protein_id="HFG9698584.1"
                     /translation="MAKAKYERTKPHVNIGTIGHVDHGKTTLTAAITKTLYDRYQLGE
                     AVDFANIDKAPEERERGITISTAHVEYETPNRHYAHVDCPGHADYVKNMITGAAQMDG
                     AILVCSATDGPMPQTREHILLSRQVGVPYIVVFLNKCDMVDDEELLELVEMEVRDLLT
                     EYDFPGDDTPIVRGSAL"
BASE COUNT         8480 a         2147 c         3846 g         6044 t
ORIGIN      
        1 tgctatataa ataataagga gggaacaatt ataaatgagg caaagaataa aaaacttaat
       61 tgaaaatgaa gataagaaaa atcctttaac agatgaagcg atttcaagta ggttaaatat
      121 tcgaagagaa gatgttacct ttttgagaaa tgagttaaaa atagaagatt caagacaaag
      181 aagaaaagtt gttttaatta aagctataaa agatatttta aaagaagaaa aaactataaa
      241 taaaaatgat ataacaagaa gattaaacag cattgggttt acagtatcaa gatttacagt
      301 catacaatac ttaaaagaga ttcaagattc tggtgaccta aaacttgata aagagagtga
      361 tgataaaaaa gaagaaataa tcaataatag agaaaataaa gatatagcat ttgataaact
      421 cataggtagt agtggtagct taagtacaat tataaaacta gccaaagcag caattcttta
      481 tccacctcat ggtcttcata ctattattat ggggccaact ggtgttggaa agagtgagtt
      541 agcagagtgt atgtataaat ttgcagtaga atcatccaga ttccctaaga atgcaccatt
      601 tatagttttt aatgcagcag attattcaga gaatccacag cttttgctat cacagttatt
      661 tggacacgtt aaaggtgctt ttacaggagc tgatgagaac aaagaaggat tagtatcaaa
      721 ggcagatgga ggaatattgt ttatagatga aatacataga ttacctcatg aaggtcaaga
      781 aatactattt caactgattg ataaaggtat ggtcagaaag ttaggagaaa caagactaac
      841 acataaaata gatgtaatga ttatttcagc aacttctgag ccaatagatt ctcatttact
      901 taatacattt aaaagacgta tacctgtaac aattgaaata ccagaattag ttgcaagacc
      961 attaaatgag aggtttgaca ttataaataa tttcttctta atagaagctc aaagaatggg
     1021 agcaaacata catataaagt cagatgtatt aaaagctctt atgctttacg attgtatagg
     1081 taatgtaggt caacttagaa gtgatattca agtagcttgt gctaggggac tattaaacca
     1141 acttacaaac aaactaaaag aagtaaatat aagcatatca gatgtacctg gatatgtaaa
     1201 acaaggtctt ataaaaatca gaaattgtag aggaaaaata gaaaattatg tagatgggga
     1261 tttaattata gactcaaatc ttcaaggtga gatagaaaag aaaaatgaag atatatatac
     1321 ttttccagat gaaatataca aacttactga aagaagacat attgatttat tggaacaagg
     1381 tttagatttt gatgttataa atagaatcat tggaggagaa ttagaaagtt gcattcaaaa
     1441 atacataaaa caagttaaaa aagtttctat tagtaacaat cttccagata taagtccaat
     1501 tgttggaaaa tatatcgtag agctaactta tgaagtaatc aaaatagcat cacaatacct
     1561 aagttcacta gaaccgaatc tacatttatg tttagcagtt cacctaaaag cagcttttga
     1621 gagattaaaa gaaggaaaag taatatcaaa tgctcatttg aaagaaataa taggaaatta
     1681 tccactagaa tattctgtag cagaaaaggt agctcaatat ttaaaggaaa gatataacat
     1741 aaacttacca aaagaagaaa taggtataat agcaatatat tttaaaatga gtagtagaag
     1801 agatatgtct gaacaaaaaa agataggtgt acttcttatg gctcacggaa gagtagcatc
     1861 ttctgtatgt gaggttacaa ataaactatt aggaattaat cacgcaaggt atttagatat
     1921 gccatttgag aagaaaccgg aagaaatgat tgaagaagct actacaataa taaaagatat
     1981 tgatgaaggt agaggtgtga ttatattagt agatatgggt tcactttcat attttggaga
     2041 tattatttct ggaaagactg gaattaatat aaggacaata tctagatttg atacattgct
     2101 ttctatagag gttatacgaa gagcagtttt accagattta acaatagacg agatagttga
     2161 tgaagttaaa ggtatagagc cacaagtaaa agaaaaggtt agtaaatgta ataatacaaa
     2221 agtagatttt agaaaaccta taattttaac attatgtatt actggattag ggggagcttg
     2281 taagataaaa aaaatcctag aggaaaatat taaaagtata actgaaaagg ttgatataga
     2341 acctataggt atgattgaat atccaagtct tgatttagag ataaaacaaa taagcaatga
     2401 taaaaatgta atcgccatag ttggaacaat tgaccctcag atagcaaata tccctttttt
     2461 tagtctagta gacataaatg ataaagcaaa gttaaatcaa ataaataacc taattgatac
     2521 aaatcaaatt ggtgaaacaa ataaaaaata tgaattatca gatttaatac ataaagaaga
     2581 tatatttgtg gatttacagg ttaaatcaaa agaagaagtt ctaaaatata tgagtaaaaa
     2641 acttagagag aaaggttatg tgacaaaaaa tttctataaa aaagtagtgg aaagagataa
     2701 cttatttcca actgaattat cagatgaaat agcaatacct cacacagatg gaatagatgt
     2761 aattaggcca gctataagta tagccatctt aaagaagcct attgtgtgga gtaaaagtaa
     2821 agtaaaaata atacttttat tagctgtaga ccaaaagtgt tttaatccat taagcactct
     2881 actctcattt atagaaacag atgaatttaa gaagataaaa aacattaaag atagagattt
     2941 tattagggag atgatattag atggagtcaa tgaaaataat tagtagcaat ttaattttta
     3001 aaaatattga agtgtctaac aatgaagatg cattaaagtt tttgggacaa cgtttgtttg
     3061 acgaacagta tgtaaaagaa agctacatac aagctgttgt agcaagagaa aaaaagtatg
     3121 ctacagggtt accaacagaa atatacggag tggcaatacc acatacagat atagtacatg
     3181 taaatgagcc aggaatagca attggaatac tgaataaacc tgtaaaattt ataatgatgg
     3241 gtacagacga tactgaaatt gatgtaaaag ttgtatttat gttagcagtg aaagagccac
     3301 aagaacaatt gcaactatta gaaaaactta tgactatatt tcaagataag aatatactaa
     3361 ataatattgt tgacttaagt gaagaaagtg tgagtgattt attaaactct aaattgaaaa
     3421 attaaacatg taaagtatat taaaaatgta aaattaaaca tgcaaagtat gttaaaaaat
     3481 ataaaaagat tattaaagat ttctaactat agatatcttt aaaataaaat aatttcaatg
     3541 ggggtgacta atgtggctaa aaagatatta gttgcatgtg gaacaggagt atgtacttca
     3601 acaattgcta taaacaaatt aaagaaagca cttcaagaca ttggtaaatt ggatatggtt
     3661 aatattacac aatgtaaagt agtagaagtt gcatcaaaag cacctgatta tgatttaata
     3721 atttgtacta cacaagtatc tagtagtata aaaacaccag tgataaatgg attacctttt
     3781 ttaactggtg tcggaatgga taaattaatc aatgatgtat tagaagagtt agaattataa
     3841 ttaaaaaaat taaggaacat ggtctctaaa atcataagtt ttagagactt aaaattaaat
     3901 aatggagggt ctttatatgg agatattaaa tttcattgtt ggtctaggtg cacaagtaat
     3961 gatgccaata ataatatgta tttttggttt gatattaggt acaaaactag gaaaatcttt
     4021 aagagctggt ttaactgtgg gagttgggtt tataggtctt aacactatta tagctttgct
     4081 aacagataat ttaggtccag ctacacaaca aatggttaag aatttagggc taagtttatc
     4141 aataatagat gtaggatggc cagcagcatc agctatagct tttgcatcaa cagtaggggc
     4201 tttaattatt ccaataggtc ttgtggtaaa tatagttatg ctaattacca atactactca
     4261 aactgttgat gtagacatat gggattactg gcattttgct tttacaggag ctttagtggc
     4321 aggggctact caaagtgtaa tgtggggagt atttgcagca gtagcaaata tggtaattgt
     4381 attggtaatg gcagatttaa ctgctccagg tatagaggaa tatttaggta tgccaggtat
     4441 atctcttcct catggattta cacaggcatt tgttccaatt gctatagtag taaataaatt
     4501 attagactta ataccaggca taaataagat tgagataaat gctgatacat tgcagaaaaa
     4561 atttggatta tttggagaac ctttaataat ggggtctgta ataggtgtaa taattggtat
     4621 tgctgcgaaa tatgatataa aaggaatatt acaattaggt gtaactatgg gagctgtatt
     4681 aatattaatt ccaaagatgg cagcattatt aatggaagga ttattaccag tatcagaagc
     4741 tgcacaggaa tttattgaga agagatttaa aaacagaggc aagatttata taggcttaga
     4801 ttcagcagta ggaataggtc atcctgttac attatcagtt gcactagtgt tggttccttt
     4861 gactatactt atagcagcta tattgccagg aaataaagtt ttaccatttg cagatttagc
     4921 agtaattcca tttgcacttg tattaatcgt accaattaca aagggaaatg tgtttagaac
     4981 attaataata ggaataatta taattacttc tggattatta atcgcaacta acttagctcc
     5041 attatttacc caaatggctt taaatgctag ttttaaaatg cctgaaggag caactatgat
     5101 ttcaagtatt tgtgatggtg cgaatccatt aagttgggta tttgtaaaag ttatgaacta
     5161 taaagttatt ggaggagtag tttttggagt tatagcttta ggaatggcta tttacaatag
     5221 gaatagaata ataaatgaaa ataaaaagct atctatagaa gaataaggtt aaaacaattt
     5281 tattaaggag tgtataggtt atgaaaaaat ataaatatga ttctaaaaga tacttactca
     5341 gtgttacaat accaggattt tttatgattt taatattgat ttatgcactg tttaataact
     5401 atacaaattt taatttgaat atatatagtt tgttaataat tgtctgtact tatggtatat
     5461 tcaatacttt tatatcatca agtaatccta aaaaaattat tattgatagc aaatgtatac
     5521 attttacctc atttatgact acacataagt atgaaattaa agatatagaa aagataagaa
     5581 taagagaatt ttataataaa aaaatttatc taaaaattaa tgatggaaaa cttttcaaag
     5641 gtaggtattg gataagaaca aatatgttta ataatagtat agcattatat agctatttca
     5701 ttgagttgga agagtgctta tatccagatt cactaaaatt tagaaataaa aaatttgaga
     5761 ataagaacat ataaaaataa aaaattgaat tgaagcctag cttaatcttt tttgataaga
     5821 tataagtttg aactttatac taaattttta gaattttcaa tcaagacaat aacataatag
     5881 ctaagcaatt agaacacaac taagatgtat aaggcatgta tatgatgaat gggaggattt
     5941 aattaatgtt attagagaaa ttaagaaaag aagtattaca agcatcttta gaccttttaa
     6001 actataattt agtgacatta acaggaggaa atgtaagtgg gagagatgaa caaactggct
     6061 atatagcaat caccccaagt ggaatggatt atagaaatct tacaccaagt gatattgtta
     6121 tagtagatgt agatggaaat attatagatg gaaaatggaa agcatcagtg gatttatcag
     6181 accacttgta tatatataag catagagaag acataaatag tataattcat acacattcta
     6241 catactcaag ttgttttgct attttaaatg aacctataga atgtgcaagt acaactcttg
     6301 caaatgaagt agggggttca gtaccagttg caaaattttc gccaccaaca tctaaaaaga
     6361 tgggaaaatg tgttattgaa gcaattggtg acaaaagagc atgtctttta gcaaatcatg
     6421 gcgtaattgc agttggtcca tctgtaggac atgctcttac agccgctgta atgttagaag
     6481 attcagcaaa agtatattac ttagcaaaat caattggcac accagtgcta ctgcctgatg
     6541 aagaaattca aagagcgaga gatgtatttt ttaatgtcta tggtcaggat aaataaatta
     6601 gataaaattt taaaagtaat atgaaaatat agatattcaa tgatattaag gagatttata
     6661 atgatataat aagtttaata gttaagaagt aaaatatgaa atgtaatagt atataaattc
     6721 atttaagact aaaaagaata agataaaata aaaaggagtc tgtatttcta tgtattactt
     6781 attaaacaaa agcacaaatc cttactttaa tttggcatta gaagaatatc tatttttaaa
     6841 tgataaatat aatgatgata ttataatcat atggagaaat gaagaatcca tttttatagg
     6901 taaaaatcaa aatccatatc aggaagtata tcatgatgtt attgaaaagg gagaaattcc
     6961 tattttaaga agaatatctg gaggaggaac tgtttatcat gacttaggta atatcaatat
     7021 gtcattcata caaaaagata ggcaacttca tgagatagat tttttggagc atactaagtt
     7081 tatgcaaaag atgctttcaa ccttaggact agatgtatct ataactgaaa gaaaagattt
     7141 atttttaaat gggaaaaaaa tttcaggctc tgcacagtct ataaaaagaa aaaattctct
     7201 ttatcatgga actcttcttt acgattcaga tttaaataaa ttaactaaat atttaaattc
     7261 aaataaagca actgaatcaa atgcaactaa atctgtttca agtaaagtta caaatattaa
     7321 gtttttactc gaaaaagata taaattactt tttagattat tgtgttgaat atttaaaatc
     7381 taatataaag aatataaaag aacttgaatt ggatgaagaa gatattaaaa gtgtatacaa
     7441 tataggagaa gataaatata aaaagataga gtggacatat ggtaaaacgc cgaaatttca
     7501 agtagtgcta ccatttaata atgaaagtaa aataaatata catgttaaca gatggaaagt
     7561 atcaaaattt tttatttctt atgatgataa tgtaattaat atggacaagt tgttagattt
     7621 gaatttcttt aaagaagaaa taaaagagag tattttagaa aattatccac attacataga
     7681 tttaatcaat ttaatatttt aatataaaac ctctaatttg ataaaattgt cttatatcaa
     7741 actagaggtt tttaatattc ttgcatatta acaaccatta caaaattgta aaattaaaaa
     7801 caacactatt gaaaaatcaa tatatattgt aataaatata tgtgtttttc attagcaaat
     7861 agacattaac tatttataca actgaaaatt taatatataa ttaatcagat ggttaaaata
     7921 aaaatattaa aagttttaat aaatgatggt taaaaataaa atacgaggtg ataccatgta
     7981 tagtgttata attgttgcag cgggaagcgg aaggagaatg aacttagata taaacaaaca
     8041 gttcataaaa ttaagagaaa aagaaattat tgctcataca attcaagttt tttatgaaaa
     8101 tataaatata gatgaaatag tggtatgtat aaaaaaagaa gaagaagatt tttttaaaga
     8161 aaatataata aataagtata actttaaaaa tataaaaata gcatatggcg gaaaagaaag
     8221 acaggactca atatataatg gtttaaaaaa attagataaa aattgtgata tagtacttat
     8281 ccatgatgga gcaagaccat ttgtcgacca tagaataatc aatgaatcta taaaggtagc
     8341 taaagaaaaa aaggctgtgg ttgtaggtgt tccagtaagt gatactataa agatagtgtc
     8401 agatggaaca gtacaagaaa ctccagaaag aaatttgctg tgggcagcac aaacccctca
     8461 aacctttgaa tataatctca taatagatgc ttatgaacaa gcatataaga acaattatta
     8521 tggtactgat gattcaatgt tggtagaaaa tataggtcaa agtgtcacta tggtaatggg
     8581 ttcttatgaa aacataaaaa taactagtcc agaagattta aatatagcag aacaaatatt
     8641 aaatatggaa aaaagagatg aagttaacag tagaaggaga attatatgag aataggatta
     8701 ggatatgatg tacacaaatt aacagaggat agaaaactta taatcggtgg tgtagagata
     8761 ccacacgata aaggtttgtt gggtcattct gatgctgatg tattgataca tgcaataatg
     8821 gattctattt taggtgctct agcattagga gatataggga agcatttccc agatacagat
     8881 gaagaatata agggagcaga tagtatgaaa ttattagaac atgtgtataa tctaataaca
     8941 agtaaaggat ataaaattgg taatatagac agtactataa ttgctcaaag ccctaagatg
     9001 gctccatata ttgagagtat gagaagtaat atatcaaaag ttttaaacac agacattgat
     9061 aatataaaca taaaggcaac aacagaagaa ggtcttggtt ttacaggagc aaaacaggga
     9121 atagcttcac aaagtatttg tttattattg ttgacaagtc agaataatta atatattatt
     9181 agtaataagt ttaatggata tcaagtaata ggcctatata gaatatctat aatgtatgaa
     9241 tttaagtgaa attaatataa atataaaatt agctatgata aagaaatagt aaaatgatga
     9301 aatcttcaca gagagaaaac ggtggtgaga gttttcaaga ggaagtcttt gaacctgtct
     9361 tttagcttaa aggtataaaa atctttacgg taggaaccgt tatattccca aaagagagct
     9421 attcatatag ctaactagag tggtaccgcg gaaattaaac ctttcgtctc tatacttgta
     9481 tagagatgag aggtttttta tattttcagg aagttaatat tcaggaggaa tctattaatg
     9541 aaaatgtcaa aaatgtttat gccgacatta aaagaaatcc cagcagatgc tgagattaca
     9601 agccatcaat taatggttag gtcaggcatg ataaaaaaaa tgacttcagg tgtttataac
     9661 caattaccaa tggggttaag agtgttcaaa aaaattgaac aaataattag agaagaatta
     9721 aataaaaaag attgtcaaga aatactttgt gcagccttac ttccttctga attatggaaa
     9781 gagtctggaa ggtggactgc tatgggtgaa gaaatgttta gactaaaaga cagaacagaa
     9841 agagagtact gtcttgggcc aacacatgaa gaagcattca ctgatataat aagacaagaa
     9901 attacttcat ataaacaatt gccactgaac ttgtaccaaa tacaagtaaa atatagagac
     9961 gagagaagac caagatttgg tgttatgaga actaagactt ttacaatgaa ggatgcctat
    10021 agttttgatg tagatgataa aggtttagat aagtcatatc aagatatgtt tgatgcatat
    10081 gtaagtatat ttaatagatg tggattggag aatagccctg tacaggcaga ttcaggagct
    10141 ataggaggtt ctacatcagc cgaatttatg gttaagtcag aagttggtga agatgaagtt
    10201 gtattttgta gtggatgtga ttatgcagcc aatgtagaaa gagcagaatc ttgtaatcta
    10261 gcatcacaaa aagaagaaat gaaagaatta gaagaggttc atacaccagg agcagctaca
    10321 ataaaagagt tagaagaatt tttaaaaact tctccagata agtttgctaa aactttagta
    10381 tatgaggcag atggaaaaac agttgtagtc gttgtaagag gagatagaga agttaatgaa
    10441 atcaaagtat ctaatgccat aggttctgtt atagaatttg ctcttgctac agatgatgta
    10501 gtgagaaaag taactaatgc agaagtagga tttgcaggtc caataggtat aaatgctgac
    10561 tatgtattta tagataaaga aattgttgaa caaagaaaca tagttgttgg ggctaataaa
    10621 actgagtacc atataaaaaa tgctaactat ggaagagatt ttgaaggaat agttggagac
    10681 tttagaaatg ttcaagaagg cgacaagtgt atagtatgtg gtaagccact tgaaatagct
    10741 agaggtgttg aagtaggaca tatatttaaa ctaggaacta agtactcaga atctatgaat
    10801 gcaaacttca tagacaaaga tggaaaatca aagcctatag taatgggatg ttatggaata
    10861 ggtgttgaaa gaacagcagc agctataatt gaacaacata atgatgagaa aggtataata
    10921 tggcctttgt cagtagctcc ataccatgtt gtgatagttc cagcaaatat gaaaaatgaa
    10981 gaacaaatat caatagctga aaatatatat aatgatttgc aagctatggg tgtagaagtt
    11041 ttattagatg acagagatga aagaataggt gtcaaattca atgattcaga attaatagga
    11101 atacctatga ggattacagt aggtaaaaat attaatgaag gtaaagtaga atttaaactt
    11161 agacataaag aagataaaga gataattgac atagaagaaa taaatgaaaa agtaaaggca
    11221 gagtttatca ggaataatgt taggttagga taataactta aataagatat tgtatagata
    11281 atcaaagttg tactttatag acaccatttt atctatatat aaggatataa aatggtgttt
    11341 ttttataaaa caaataaatg aggaggtaat taaaatggca aaaaatgaaa aacaatttgt
    11401 tgaagaaata acaaagatgg aagatgattt tccacaatgg tacacagatg taataactaa
    11461 gactgactta gttgattatg ccccagtaaa aggttttatg gttgtaaagc catatggata
    11521 tgcattatgg gaaaagatgc aagaatttat ggataaaaaa tttaaagaaa ctggacataa
    11581 aaactgttat tttccattat taataccaga gagtttatta aacaaagaag cagaacacgt
    11641 tgaaggtttt gctccagaag ttgcatgggt aacacatgga ggaaataaaa aattagaaga
    11701 aagattatgt gtaagaccta cttcagagac tataatatgt acaatgtatg cgaaatggtt
    11761 aaaatcatat agagaattac catatcttta taatcaatgg tgctcagttg ttagatggga
    11821 aaaatcaact agacctttct taagaacatc tgagttttta tggcaagaag gtcatacgtt
    11881 acatgaaaca gcagaagaag cacaagaaga aacaatacaa caattagaag tatataaagc
    11941 gctatgtgaa gaattacttg caatgccagt tgtagctggt caaaaaagtg aaagtgagaa
    12001 atttgcaggt ggtgaaagaa catatactat agaagctatg atgcatgatg gtaaagcatt
    12061 acaatcaggt acaagtcact tcctaggtca acactttact aaggcttttg atattacttt
    12121 tgcagatagg gaaggaaatt tagctaatcc ataccataca tcttggggag catctacaag
    12181 acttataggt ggacttataa tgactcatag tgataacaga ggtttagtat taccaccaag
    12241 agtagctcca attcaagttg ttatagttcc tatagctgct aaaaaaggaa atgtaatgga
    12301 gactgttgat aaaatatatg ctgatttaaa agctaaggga gtagctgtag aagttgatga
    12361 tagagataac tatacaactg gatggaaatt taatgagtgg gaaatgaaag gtgttccagt
    12421 aagagttgaa attggaccaa aagatataga aaataatcaa gctatggtat ttagaagaga
    12481 tactttagaa aaggattcta tgcctttaga aggattagct gatgctatat gtgatttatt
    12541 tgatgttata cacaatgata tgtttgaaaa agcaagaaaa catagagaag acaatacatc
    12601 tatagttgaa aatatggatg agtttagaaa agctttagaa gaaaagccag gattcataaa
    12661 gactatgtgg tgtggagatg cagaatgtga agctaagatt aaggaagaaa caggagcaac
    12721 tataagatgc ttaccttttg aacaagaaaa cttaggtcac aagtgtgtgt actgtggaaa
    12781 agaagcagat agtatggtag taatggcaaa agcttactaa aatacattta aataaaaact
    12841 ggggtagaaa gtatttaata ctttatccca gttttttgtt ttttatgagt aataaaatgt
    12901 atttgtaact atgtcataag ataagtcata gatacttata ttaaaaagaa tataatagag
    12961 aactattttt aataattaca tattaatgaa agcaaaatat tttgttatat agattttcaa
    13021 taaagcaaac aataaatata aatgaatatt aataaggagt gcttttaatt tttagaaaat
    13081 aaatgactta aaagaaagat ttatgaaatt aaaactagga ttttctgata taataaacat
    13141 gtgtattttt aaataaaaag gatattatta ttagatttga ttaaaaataa acttgcaaaa
    13201 caatgtacta gtttaatatt atagttatat tgaataaaat atcaggagga agtaaaaatg
    13261 aatgtaagag taaggtttgc accaagtcca acaggatttg tacatatagg tagtttgaga
    13321 actgctttat ataactattt atttgcaaaa aaaatgggcg gagaatatat attaagagtg
    13381 gaagatacag accaaagtag attagtagaa ggtgctatag agaatatgct taatgctatg
    13441 aaatgggctg gggtcaacca tagtgaaggt gttatattag atgatagtgg aaaagtagta
    13501 caaaaaggag aatatggtcc atatattcaa tctcaaagat tagatatata ccaagaatat
    13561 ataaagcaac ttttagatag tggaaaagct tattactgtt tctgtacaaa agaaagactg
    13621 gatgaagtaa gagatgctca aagagcagca ggagaaacag ctaaatatga tggtcattgt
    13681 aagaatcttt ctaaagaaga agtagaagcg aatataaaag caggaatacc atatgttata
    13741 agattaagat tgccagagaa tcatacaatt aagtttacag acttagttag aggagatatg
    13801 gaatttaata ctaatgactt agatgaccaa gtattaatga aaacagatgg atttccaact
    13861 tatcattttg cagtagttgt tgatgactat ttgatgaaaa ttacacatgt tataagagga
    13921 gaagaatggg tatcatctac tccaaaacat gtttatttat atgaagcttt tggatgggaa
    13981 gcacctgtat ttgtgcattt accaaatata cttaataaag aaaagaaaaa attaagtaaa
    14041 agacaaggtg atgtagctgt tgaagacttt aagaaaaaag gatatttacc agagggatta
    14101 gtaaactatg tagcattagt tggttggtct cctgaagata atcaagaatt gtttacaatg
    14161 gaggaattag aaaaagcctt ctctgtagaa agagtatcta aaagtggtgg agtatttgat
    14221 actgaaaaat taaattgggt taatcagcac tatataaaag atggtgatga tgcttatcta
    14281 acagacttag caataccatt tttaatagaa gatggattta taacagaaga agaagctact
    14341 aataaatatg atttcttaaa gagtatgata tcagtactta aagagaaatt acaatatgta
    14401 aaagaagtta ctgaacatgc aagtatattt tttggagata aaatagaggt agaaactgaa
    14461 gagggaagag agttcttaag attagaacat atacctactt taatagatgc tttgagagaa
    14521 aaaatagaaa aaacagaggt attaaatgct gagtttgttc aagctatgct taaagaaata
    14581 caaaaagagt acaaaataaa agggaaaaat ttatttatgg gctcaagaat aattttgaca
    14641 gggcaaatgc atggtccaga tttaccaaaa gtaatggaag ttttaggaaa agaaacttgc
    14701 ttaaatagaa tagcttatgt aaaaaataat atattatagt cataaaagtc cgctaattta
    14761 gaagcggact ttttttgtgt tagtatttgg tgaaaatatc tgcttaagaa aatgaaggta
    14821 tttaaggtaa taaatttaat atataaaaag caaagcaaaa atataaataa aatatgaata
    14881 ataaactaat aaaatattaa gcatagaaga agggaatcta ttattttagt ttgatttaat
    14941 tattaagggg gtaattacta tgtatagtaa tattgatgat gttaaaaagg aattaaagga
    15001 gctatgctta gaatatgtta caattttaga aaaattaaaa gatgaaaaaa tgattacaga
    15061 agaaactttt gaaaagtgct cttctcaaaa aaaaatattt ttagaagaac aatagaggat
    15121 ggtaatagta ttattattat gtagtttgaa agatagtacg aaaaatgata gtaatactat
    15181 tatttattgc aattttcaac tataatataa tatataatgt taagaagata atttataaaa
    15241 atacagtgag gtgatgagtg tgaaagttta taatacattg actagaacaa aagaagaatt
    15301 tgttccatta gaagaaggaa aggtaaaaat gtatgtgtgt ggtccaacag tttataacta
    15361 tatacacata ggtaatgcaa gaccatttat aatatttgat actctaagaa ggtatttaga
    15421 gtatagagga tatgatgtaa cttatgtaca aaactttaca gatgttgatg ataagattat
    15481 aaatagaagt catgaggagg gaatatctcc tgaagaagtt gcggctaagt atataaaaga
    15541 atattttgta gactgtgatg ggctaggaat aaaaagagct actgttcatc ctcaggttac
    15601 agataatata caacagatta tagagtttat aaaagagttg gaagataagg gatatgcata
    15661 tgcagtaaat ggtgatgtat attttgatac aaataagttt gaaggttatg gaaaactttc
    15721 aggtcaaaaa caagaagatt tagaggcagg ggctagaatt gaggttaatg accaaaaaag
    15781 acatcctatg gactttgttc tttggaaggc aaaaaaagaa ggtgagccag gatgggatag
    15841 cccttgggga gaaggtagac caggatggca tatagaatgt tctgttatgt ctaagagata
    15901 tttaggtgaa acaattgata tacatgcagg tgggcaagat ttaacattcc cacatcatga
    15961 aaatgaaata gctcaaagtg aagctagaag tggaaaaaca ttctcaaaat actggatgca
    16021 taatggatat ataaatataa atgatgaaaa gatgagtaaa tcaaaaggta atttctttac
    16081 agtaagagat atatcaaaat tatatgattt agagatagta agatttttca tgttatcagc
    16141 acattataga aatccagtaa actttagtga tgagatgtta aatcaagcta aagcaggtct
    16201 tgaaagacta tataatacta aagaaaaatt agaatttacg ctaagtaatt tagtagaatc
    16261 tcctttaaca gaaaaagaag tagagcttgt taaagaatta gatgacttta gacaaaaatt
    16321 catagatgct atggatgatg atgttaatac agcagacgca gtaagtgtaa tatttgaatt
    16381 agctaagtta ataaattcta atgtagatga aaattcttct ttggagtttg ctaaaaaatg
    16441 cttagatgaa tttaatgaac ttacaggagt attaaatatt gtaaataaga aaaaggatac
    16501 tgtattagat aaagacattg aagaattgat acaaaaaaga actgatgcaa agaaaaataa
    16561 agagtttcaa ttagctgatg atattagaca acaattacta gatatgggaa ttgtattaga
    16621 agacacaaga caaggtgtta agtggaaaag gatataaaaa tggaaaaaac tgaattagtt
    16681 actatgtcac cattagtttt agcatactta ggtgatacag tgtatgagac atatataaga
    16741 gaatatttaa ttagacagaa tacacaaaga aaagttaatg atttgcataa actagctata
    16801 aagtatgtaa aagctaaagc tcaggcaact ataattcatg aagttgaaat tgagttaact
    16861 gaagaagaga gtaaaattta taaaagggga agaaatcaaa agtcaaatac ttctcctaag
    16921 aatgcagata ttatagacta caaacatgca actgggtttg aggcattagt tggatatttg
    16981 tatttaaata atgaaataga gagacttcaa tatattatca ataaaggaat caaaattatt
    17041 gaaagagata tgtaaatatt aaagagtgtt gtcttaataa taagtaataa ggcaacactt
    17101 tttttataac taatgtataa taaatatata gaaattagta atgagaaagg ataaaaagtt
    17161 atgaaagtaa aattaatatc acatacacct gaaccagaaa aagtaatagc tatggcagct
    17221 aagctatgtt attcaccagt tgggacagac gaaatagaaa aagacttaac agatgaaagt
    17281 atagagaaat ttttaaatat gttattaagt ataggtcatg ggtcaatatt agaacatgct
    17341 tcatttacat tttcaataga aggtatttca agggcatgtt cacatcaaat tgttagacat
    17401 cgtatagcta gtttttcaca acaaagtcaa agatatgtta aattagaaca atttgagtac
    17461 ataattcctc cagaaataga aaaaatagaa aaggcaaaag agttatttat agactccatg
    17521 aaaaaagacc aagagaatta tgataagtta gttgaaatat tgtttgaaaa tcattataat
    17581 gacctaataa aaaacggtaa aaatgagaaa acagctaaaa gacaagctga gaagaaagca
    17641 atagaagatg ctagatacgt atttccaaat gcatgtgaaa caaagatggt atttactata
    17701 aatgctagaa gtttgtttaa tttctttgaa catagatgct gtgaaagagc acagtgggaa
    17761 ataagaaatt tagctgtgga gatgttaaga gaggttaaaa aggttgctcc tatattattt
    17821 aaaaagactg gtccaagttg tgtaaatgga agttgtccag aaggaactat gacttgtgga
    17881 gatatagttc aagttagaga aaaatttaag gccttgtagg aggtgaataa tttggcgagt
    17941 atagaaggaa gaaatccggt aatagaagca ataaaaagcg acagagaaat agataaaata
    18001 ttaattgcaa attcagctaa agaaggttca attaagaaaa taataggaat ggctaaagat
    18061 aagaatataa ttattcagta tgttgataaa cataagttag atgaagtaag tacaagtcat
    18121 tcacatcaag gtgtaatagc ttatgcaagt gagtataagt attatgaatt agatgagcta
    18181 atagatttag caaagaataa agatgaagac ccatttttca ttatattaga tgagataaca
    18241 gacccacata atttgggttc aataataagg acagcagatg cagtaggagc acatggagtt
    18301 atcattccaa aaagaaggtc tgtacacata actcctgtag ttgccaaagc atctgctgga
    18361 gcagtagaat atatgccagt ttgcaaggta accaatatag ttaatacaat aaaaagactc
    18421 aaagaagaag ggctgtggat tgctgcagct gatatggatg gagaaacttt ttataaacaa
    18481 aatcttactg gtcctcttgg tgtagtaatt ggaagtgaag gttttggaat atctagattg
    18541 gttaaacaaa actgtgactt tatagtaaaa atgccaatga taggtaatgt tacatcttta
    18601 aatgcatctg tagcaggtgg aatactttta tatgagatat tcagacaaag actggataaa
    18661 agtaaatagg catgaaaaaa aatataaatc attacttaat aatagatggc tacaatatta
    18721 taaatgcgtg ggacaatttg aaagaactgg ctaaagagga cttagaagat tctcgagaaa
    18781 agcttattga tgacattata gaattttctg agtttatggg ttataagact ataatagttt
    18841 ttgatgctta taatgttaaa aattctcgag aaaaagttga aaaaagaaaa cacataacaa
    18901 tagtttatac aagagaacac caaacagcag atagttatat agagaaattt ataacttctt
    18961 tatcaaagta tgatgatgta aaagtagcca ctaatgacta tgcagaacag caaatgattt
    19021 taggaaaagg tgctactaga atgtctgcaa gagaattaaa gttagagtta gatcgttcca
    19081 agaataaaat gaaggaaaaa aatatcggtt tgaggaaaaa aattcagcga aattggttgg
    19141 aggaaaggtt agataaagaa acattgtcga aacttgagaa cattcgtaga aagcgttgaa
    19201 attactaggt tctttagact ataatatacc tataaatttg ttttatatat gggggagatt
    19261 tacatgttgg tagcaaaaga aaaaagttat gagttagtgg acaattgtca gcaggatgag
    19321 tataacattg tattaagagc aagtgaaggg gataaaatag cactagagta cattattact
    19381 aaatacagaa attttgtaaa ggcaaaagca aagtcatatt ttttaattgg agcagataaa
    19441 gaagatataa tacaagaagg aatgataggc ctttataagg cagttagaga ttttgatgga
    19501 agtaagacca attcatttaa atgttttgcg gagatatgta taacaagaca aataataact
    19561 gctataaaaa ctgcaacaag acaaaaacat atacctttaa attcatatgt ttctttgaat
    19621 aaaccaatat atgatgaaga gtcagacaga acacttttag atattatagc tacaagtata
    19681 gtaacagatc cagaagagct tataattagt aaagaagagt taaaaaatat agaatcaaaa
    19741 atgaacgaat tgttaagtga cttggaatta gaagtactag aattatattt aaatggaaag
    19801 tcataccagt ttatagcgga caagcttaaa agagatgtaa agtcaataga taacgcttta
    19861 caaagggtta agagaaaatt agaaaaacat cttgaaaaca gaaatgatta atagtaaaat
    19921 acttaccata agcttattgt gagcaaaatt aatttatatc gaaagataag ggaggaaatt
    19981 caaaatggct aaagctaaat acgaaagaac aaaacctcat gttaatatag ggacaatagg
    20041 acacgtagac cacggtaaaa ctacattaac agcagcaata acaaaaacat tatatgacag
    20101 atatcaatta ggagaagcag tagatttcgc aaacatagat aaagctccag aagaaagaga
    20161 aagaggaatc acaatatcaa cagcacacgt tgagtatgaa acaccaaata gacactatgc
    20221 acacgttgac tgcccaggac atgctgacta cgttaagaac atgataacag gagcagcaca
    20281 aatggacgga gcaatattag tttgttcagc aacagatgga ccaatgccac aaacaagaga
    20341 gcatatacta ttatcaagac aagttggagt accatatata gtagtattct taaacaaatg
    20401 tgacatggta gatgatgaag agttattaga gttagtagag atggaagtaa gagatttatt
    20461 aacagaatat gatttcccag gagatgacac tccaatagta agaggttcag cattaat
//
LOCUS       DAYAOO010000073        20244 bp    DNA     linear   BCT 12-OCT-2024
DEFINITION  TPA_asm: Clostridioides difficile isolate ST8-SSI-h139-18
            SAMN40601845-rid21577343.denovo.073, whole genome shotgun sequence.
ACCESSION   DAYAOO010000073 DAYAOO010000000
VERSION     DAYAOO010000073.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN40601845
            Sequence Read Archive: SRR28438827
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 20244)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 20244)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-MAY-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-MAY-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002157583.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002157583.1
            Genome Coverage       :: 163x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/11/2024 16:19:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 4,038
            CDSs (total)                      :: 3,963
            Genes (coding)                    :: 3,930
            CDSs (with protein)               :: 3,930
            Genes (RNA)                       :: 75
            rRNAs                             :: 6, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 60
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 33
            CDSs (without protein)            :: 33
            Pseudo Genes (ambiguous residues) :: 0 of 33
            Pseudo Genes (frameshifted)       :: 7 of 33
            Pseudo Genes (incomplete)         :: 25 of 33
            Pseudo Genes (internal stop)      :: 11 of 33
            Pseudo Genes (multiple problems)  :: 8 of 33
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..20244
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN40601845-rid21577343.denovo.073"
                     /isolate="ST8-SSI-h139-18"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Denmark"
                     /collection_date="2018"
                     /collected_by="Statens Serum Institute"
     gene            <1..352
                     /locus_tag="ACGI5H_002888"
     CDS             <1..352
                     /locus_tag="ACGI5H_002888"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728538.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HFG9698585.1"
                     /translation="FKVLSDEKWLYFIFEQLLSNSLKYSSLGDNISIYCKRTKNYLQL
                     RVEDTGCGIKKEDLNRIFNKGFTGNNGRNNSKSTGLGLYLVKELCDKLGHKIDVDSEY
                     NQYTKFTITFKCDL"
     gene            464..1693
                     /locus_tag="ACGI5H_002889"
     CDS             464..1693
                     /locus_tag="ACGI5H_002889"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436742.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_function: GO:0042802 - identical protein binding
                     [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="efflux RND transporter periplasmic adaptor
                     subunit"
                     /protein_id="HFG9698586.1"
                     /translation="MSFLKKFKNKRFRNNSFKSNNFRNSSFGSSGFKSKNKGFKNNPF
                     KNKRFKIYAGIAVIILLILGVLAYVDSKNTELQANENFIETYTIPENEKIFINGMVVP
                     KQTKDFNISGDYELSDVNVTNGQKVNQGDLLFTAKNPTIIAEIDSLKSQLSQYKKQKI
                     SLSDIAENKDAIASINAQITALSSQIASLDKKAYDRVTAPFDGTVYLNDQTGNPDQPV
                     SFMTIQGLEFYMKGQASEQDLPKMKIDQMVNILVFSTDQKLTGRISFISDKPSTPNTE
                     MGAQQNTLSYYDINIAFDNQEGLVNGFHLQASLEVANSSFKIPASCVLKDNKHSYVFK
                     DLDGILKKQIVDVASQNDDFAVVRGGLEQGDIIIKHPTKEMKEGDPVQGDGVTAGSNN
                     GDTTPNKKVEEVTMDVN"
     gene            1701..2375
                     /locus_tag="ACGI5H_002890"
     CDS             1701..2375
                     /locus_tag="ACGI5H_002890"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889377.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HFG9698587.1"
                     /translation="MLIKLENIQKYYKVGKDELHVLKSLNLEIESGEFVMIMGKSGSG
                     KTTLLNILGFLDVFDEGRYIFDGTDVTNLSENERSVFRNINIGFVFQQFNLIETLNVY
                     QNVELPLIYNKALKKSNREEIVKDKLSSVGLLDKLKQKPLQLSGGQQQRVAIARCLAN
                     DPQIIFADEPTGALDSETSREIMELLTRLNKQGKTIIMVTHDQDLTKYATKVIRLKDG
                     VFTSEV"
     gene            2378..3610
                     /locus_tag="ACGI5H_002891"
     CDS             2378..3610
                     /locus_tag="ACGI5H_002891"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420052.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HFG9698588.1"
                     /translation="MSLLKNSLANLKGHKLRVFVALLWIIIGITSVILVSSIGNGFQK
                     EIKKSVNNVNPNKTTISFESADNTGLTDDMSIFLKPFNAKDLEELSFVEGVERIAPSR
                     DGFNLDSVYSSQASFDKKTTYVDVGPVKKDSKINLICGRDFSLDDEKRKVILLTLQST
                     SEIFENPEDALGHGININGTIFEIIGVLDDSQQNQAGGFFGGYQDMQFTTSLVPKKAF
                     DTLMSQNSYSNEIYQLDLVSSKGYNVNEVANNVIAKLYEMHPGINGSYTTPDPTEQTA
                     YLESINSNVNKYVSIITVVAMFVGGIGVMNIMYVSVMERQREIGIRRAIGAKPRSILF
                     QFLVEAVFITVCGGILGTIVGFTATNYVSKYIGFEAIPSLNSLFYAIVATILTGVVFG
                     LIPAFKASKLDPIKAIYK"
     gene            complement(3896..5161)
                     /locus_tag="ACGI5H_002892"
     CDS             complement(3896..5161)
                     /locus_tag="ACGI5H_002892"
                     /EC_number="3.5.2.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420051.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004151 - dihydroorotase activity
                     [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0006221 - pyrimidine nucleotide
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroorotase"
                     /protein_id="HFG9698589.1"
                     /translation="MILIKNGRVIDPKSQRDENIDLIIKENKIYKIGKFDESDEYEKI
                     IDASGNVVAPGLVDVHVHFRDPGFTYKEDIESGAKSAARGGFTTVICMANTNPIVDNE
                     DTFNYVKEKSKNACINVLQAAAITKGFEGKELVDMEALKKAGVPGFTDDGLPLMDSNL
                     IMEAMIKAKELDVPLSFHEEDPSLVGNPGVNAGKVASELGLKGASSVAEDVMVARDCM
                     LALKTGAKVDIQHISSGVSVDMVRFAKYLGANVVAEASPHHFTLTEEDVLEFGTNAKM
                     NPPLRSKWDRDKIIEGLNDGTIEIIATDHAPHSKEEKDREFIKAPSGIIGLETSLALG
                     ITNLVHKNHLSMMQLIEKMSINPAKLYNLNIGFIEEGAVADIVIFNPEEEWTVESFVS
                     KADNSPFKGKSLYGKVNYTICNGEIVYNA"
     gene            complement(5214..6362)
                     /locus_tag="ACGI5H_002893"
     CDS             complement(5214..6362)
                     /locus_tag="ACGI5H_002893"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429751.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF362 domain-containing protein"
                     /protein_id="HFG9698590.1"
                     /translation="MKSVSVRSCKTYNYEEVKLSIEKNLEDIGGIDKFVKKGSKVLIK
                     PNLLMKKKPEEATTTHPMVVKVVCEKLLELNCDITIADSPGGPYNQSSLKSIYKASGI
                     EEVANELGIKLNYDVSDVKIHSEKAHVLKYMDIIKPIVDSDYIINLCKLKTHIMATFT
                     GGTKNLYGCIAGLKKAEIHYRFPTEELFCENVLLDICDYIKPTLTIMDGIVGMEGDGP
                     SAGTTREIGVLLASQNPYAIDVVACKIISLLPNRVATIRGAIKRGYIQEDFSDIEILG
                     EDIKDLIIKNYKIPNVSKDLRLFSVKLPKFLNEPISKLITPKPVVRFQDCIKCGKCKE
                     ACPASTIEIGTKGAIIDLSKCIRCYCCHELCPKKAIDVKRNFVFKYVK"
     gene            complement(6453..6998)
                     /locus_tag="ACGI5H_002894"
     CDS             complement(6453..6998)
                     /locus_tag="ACGI5H_002894"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012816134.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADH peroxidase"
                     /protein_id="HFG9698591.1"
                     /translation="MKKFVCTVCGYIHEGDAAPAQCPVCKVGADKFEEMKGEMVWADE
                     HRIGVAQGVDAEIIEGLRANFTGECTEVGMYLAMSRQADREGYPEVAEAYKRIAFEEA
                     EHAAKFAELLGEVVVADTKENLRVRVDAEYGATDGKLKLAKRAKELGLDAIHDTVHEM
                     CKDEARHGKAFLGLLNRHFGK"
     gene            complement(7221..8165)
                     /locus_tag="ACGI5H_002895"
     CDS             complement(7221..8165)
                     /locus_tag="ACGI5H_002895"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902550.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DMT family transporter"
                     /protein_id="HFG9698592.1"
                     /translation="MQKNKKEGALLKKYFGEIGLIFIAIIWGSGFVATQFALDGGLTP
                     LQIITLRFFLAAIIMNLLFFKQIRANMGKKLLKAGGILGIFLFLAFTVQTIGLMYTTP
                     SKNAFITAANVVIVPFIGFILYRRKLDKIGIISSLVALIGIGILSLEADFSINFGDFL
                     TLICSFGFAFHIFFTSEFAKDNNPMALTAIQFTVAFLMSVVVQTFAGQLKMEAELSGY
                     MGTMYLAVFSTTIGFLFQTICQKRVDGTRTAIILSTEAVFGTIFSIIILKELITAKLV
                     IGSILIFVAIITAETKLSFLKSKKVKLKDSEESSLESI"
     gene            8551..9432
                     /locus_tag="ACGI5H_002896"
     CDS             8551..9432
                     /locus_tag="ACGI5H_002896"
                     /EC_number="3.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420045.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016810 - hydrolase activity, acting on
                     carbon-nitrogen (but not peptide) bonds [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide deacetylase family protein"
                     /protein_id="HFG9698593.1"
                     /translation="MVKKRKKKTVTLTILVVIVIGIFSMAWADMSRKKEMKETQERLK
                     AERLEKERIEKEKNEPIIGAKKEAVKEYGYDAKIVWDKLNKYDYSNNGEKIVFLTFDD
                     GPSTTNTPQVLDILKRHGVRGTFFIKGDSLERKGANEILKRTFDEGNAIAHHSYTHDY
                     KKLYPNRSLNLDTFVNELNKTDEAMKKVLGKNFSSNVVRCPGGYMSWKNMEPLGNYLK
                     EKNMASIDWNALNADAEGKKKNAQELFEHAKKSSEGKEMVVLLMHDTYGKQETVNALD
                     QIITYFKDNGYQFKILI"
     gene            complement(9493..10701)
                     /gene="tyrS"
                     /locus_tag="ACGI5H_002897"
     CDS             complement(9493..10701)
                     /gene="tyrS"
                     /locus_tag="ACGI5H_002897"
                     /EC_number="6.1.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420043.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0004831 - tyrosine-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006437 - tyrosyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine--tRNA ligase"
                     /protein_id="HFG9698594.1"
                     /translation="MKSIDEQMRIIMKGVDDLIDEKELREKLIKSEKEGKPMIVKLGL
                     DPSAPDIHLGHTVVLRKMKQLQDLGHQIVIIIGDFTGKIGDPTGKSKARKALTTEQVL
                     ANAKTYEEQIFKVLDKEKTIVRFNSEWLAKLNFEDVIKLAATITVARMLEREDFKKRY
                     EGQMPISVHEFFYPLMQAYDSIALEADIELGGTDQRFNLLMGRSLQREFGMESQIVIM
                     MPLIEGLDGKEKMSKSLGNYIGIDEEAGIMYQKSMEIPDELIIKYYNLVTDVHPDEVN
                     KIESQLKEGSVNPRDIKMNLAREIVTLYHGEESAKEAEERFKSVFQKGQIPEDIQTIQ
                     VKEDGFDLIEVLVSNEIVKSKSEVRRLASQGGVKVNGEKVEDLSTIVKESELVVQIGK
                     KKFVKIELVK"
     misc_binding    complement(10774..11026)
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            complement(11178..12146)
                     /locus_tag="ACGI5H_002898"
     CDS             complement(11178..12146)
                     /locus_tag="ACGI5H_002898"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729368.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2232 domain-containing protein"
                     /protein_id="HFG9698595.1"
                     /translation="MNTTKKLTEAALLSSLFIVVTIIAVSTGFGYAIYLDFIVPVFFC
                     IICLKCDLKYTILSGITSLLIISLVLGNLGTAIWASQSVLLGIMCGYLINKPTMVMDD
                     LVYGSVFGLIVMVFIDIYASTLIGYSFMKEFQGYSKWIYFNGYTNFIYYLMIALFPFG
                     MVFCIYLLSLILGNKLHILDSNSLKKFLIFKNFRSLNQFLCCSKKAFYICVSYLAIFE
                     VLKLLNVKVDSVYLKTIFISITYISLYFIIRDSCMSLQNFIIAKFRKLLYARILFLII
                     ILLLFFIFDVTVIGLIIINAFLNKKINIRLSQSNIVNKQINLLIEK"
     gene            12319..12759
                     /locus_tag="ACGI5H_002899"
     CDS             12319..12759
                     /locus_tag="ACGI5H_002899"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427501.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HFG9698596.1"
                     /translation="MFKIKHFNDLSLDEFYEIAKSRYEVFACEQKIFSLNDYDDIDKN
                     SYHIFLKENGLICAYARIIPKEYSSYNDVSIGRVLVLSSHRRKGLAKQMMDCAIDFIK
                     VNLHENNITLSAQTYIKNLYLSCGFKEISEVYDEAGIEHIKMRL"
     gene            13086..13313
                     /locus_tag="ACGI5H_002900"
     CDS             13086..13313
                     /locus_tag="ACGI5H_002900"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420037.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ferrous iron transport protein A"
                     /protein_id="HFG9698597.1"
                     /translation="MKNLNDIQVKKTVKVEDILSSGNLRERMLALGLTRGAVIDVVRK
                     GPKNNLTVYKIRGSKIALRQEESSLILVSDI"
     gene            13339..15459
                     /gene="feoB"
                     /locus_tag="ACGI5H_002901"
     CDS             13339..15459
                     /gene="feoB"
                     /locus_tag="ACGI5H_002901"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439379.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_function: GO:0015093 - ferrous iron transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0006826 - iron ion transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ferrous iron transport protein B"
                     /protein_id="HFG9698598.1"
                     /translation="MGLTHNSTKMSSLKDMFDIDNKEDQFVIALAGNPNTGKSTVFNH
                     LTGLRQHTGNWPGKTVATARGNFKYKNTEYALIDLPGTYSLFALSQEEIVARDFICFG
                     NPDAVIVVCDATCLERNLNLVFQVMELTDKVILCINLIDEARKKGITIDKKLLEDSLG
                     IPVILTAARNGSGMDELLDTLNDVSFDKYKLNNKPVRYNENIENVVKSIQPELDNIIP
                     GINSRWLGLRLIDGDESIFESMSNYIDKNSIDAINEVKKKIPDNINKQKIRDEFTKIN
                     YDYAKKLSDECCSNVAKKSTDREEKVDKILTSKIFGLPIMLLLLGTILWITIEGANYP
                     STLLSNLLLGFEPSISGILNSINCPSWLNDMLVLGLYRTLAWVISVMLPPMAIFFPLF
                     TLLEDFGYLPRVAFNLDHLFKKACAHGKQCLTMCMGFGCNAAGVIGCRIIDSPRERLI
                     AILTNNFVPCNGRFPTLIAISTIFFSSVITNSFVSSVATALCITLLIILGVIITLLVS
                     YTLSKTLLKGVPSTFTLELPPYRVPQIGRTLYTSIIDRTIFVLGRAVMVAIPAGVITW
                     IFANIYIGDLSILSHVANFLDPLAKLIGLDGFILLAFILGFPANEIVVPILLMAYLAT
                     GSMIELDSFSALGQVLREHGWTYLTALNVMLFSLLHWPCATTLLTIKKETGSLKWTAL
                     GFLMPTILAFVVCFLTTTVYNLFI"
     gene            complement(15592..16410)
                     /locus_tag="ACGI5H_002902"
     CDS             complement(15592..16410)
                     /locus_tag="ACGI5H_002902"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893097.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HFG9698599.1"
                     /translation="MEKQYFTTGEFAKLCGISKQTLIFYDKIGIFSPEYKDKNNYRYY
                     SVYQYDTLDILQSLREIGMSLEEIKEYIQNRTPQLCVKMLKEEEKKIREKIKKLRKIS
                     SKMQNRINITVEGISKMNSEEIYISKKFEEYLVLSSDLSNMSNSDFMMELIDFTNYCK
                     SKNLYQGYELGVIVSNENIKNGDYLSISSFYLKIDKKIKDKKLYVKPEGMYACIKHIG
                     KYEDSYKSYEKLKKYIYENEYKIVGNSYEESILDFFCESNEDNYMTEISIQVSR"
     gene            16629..16901
                     /locus_tag="ACGI5H_002903"
     CDS             16629..16901
                     /locus_tag="ACGI5H_002903"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896473.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9698600.1"
                     /translation="MKIVIGATIRYLIKHKVNYCNKKSLDKLELKYGNIDREKAVKLE
                     IFYQYLIELEYIEMSLLIRRLDTAITSLALVSIITIASYYLIRKNV"
     gene            complement(17954..20047)
                     /gene="pdcA"
                     /locus_tag="ACGI5H_002904"
     CDS             complement(17954..20047)
                     /gene="pdcA"
                     /locus_tag="ACGI5H_002904"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902545.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="c-di-GMP phosphodiesterase PdcA"
                     /protein_id="HFG9698601.1"
                     /translation="MNKHNFEVILNQLQINIYVTNIHTNEIIFMNKKMKEEYNILDPE
                     GKVCWQVLYPEKNSTCSFCKVLELLKNDKKGVLIKWYEKCNKLNRVFENYDSLITWQD
                     GTVVHMHQSIDIANSTSLNKPIKINEFHEISNNKEEKGVFNFSRDNFDYNSTLLYDAL
                     IRGTDEYIYICNMKTGVFRYSPSQVELFDLPGEIVKNPLVYWKKIVHPEDWNRFYKSN
                     TEIGKNQMDYHTVEFRAKNRSGEYIWLRCRGQLMRDEFGEPSIFAGIMTQLGKQNKID
                     SLTQLLNYHEFMSVFEDKISNPMIEKLCIVLLDIDDFKNVNEMYDRDFGDNIIKTLAQ
                     SVQSILPDNAELYKLDGDEMGILVDNVEENEILTLYNQIQNMIIHLQLWRKYGLNITI
                     SAGCVIYPKHGDTVKELYKCASYSLQYAKEHGKNRLVFFSQEILKNKMYSLEMMRDLK
                     ASINDDFRGFSLRFQPQVDTESHKIIGVEVLLRWTNDKCKAISPLEFIPILEENDMIN
                     IVGAWVLRMALRTFRKWIDYYPFFKVSVNVSAVQILEDTFIEDIVKIIDDENFPYQNL
                     VLELTESHTVQNMSILQFKFKALQDLGIYIAMDDFGTGYSSLEVLKFSPIDIVKIDRV
                     FVKDILKSKFDATFIHFIVAICHDVGIKVCLEGVETQEEYDLVKQIKPDYIQGYLFGK
                     PQTATEIFDLLKLDN"
BASE COUNT         7111 a         3133 c         2523 g         7477 t
ORIGIN      
        1 ttttaaggtt ttatctgatg aaaaatggct atacttcata ttcgagcaat tattgagtaa
       61 ttccctaaaa tactcctcat taggagataa tatatctatc tattgcaaaa gaaccaaaaa
      121 ttatttacaa ttaagagtgg aagatactgg ttgtggtata aaaaaggaag atttaaatcg
      181 aatattcaat aagggattta caggtaataa tggaagaaac aattctaaat ctacaggtct
      241 tgggctttat ttagtaaaag aactttgtga taagcttggt cataaaattg atgtagattc
      301 agagtacaac caatatacaa aatttactat tacattcaaa tgtgatttat agtatcttat
      361 tattgatagt ttattttcat taacttatat tcaacttctt atagtaattc tatatgtaca
      421 tcccagtata taattaagta gtttttataa aaaggaggaa gacatgtctt ttctaaaaaa
      481 atttaaaaat aaaagattta gaaataacag ttttaaaagt aacaacttta gaaatagcag
      541 ttttggaagt agtggcttca agtctaaaaa taaaggtttt aaaaacaatc cctttaaaaa
      601 taagagattc aaaatatatg caggaatagc agtaatcata cttttaattc taggagttct
      661 tgcttatgtt gattcgaaaa acactgaatt acaagctaat gaaaatttta tcgaaacata
      721 tactattcct gaaaatgaaa aaatatttat aaatgggatg gttgttccta agcaaactaa
      781 ggacttcaat atatctggag attatgagtt aagtgatgtt aatgttacaa atggtcaaaa
      841 agtaaatcaa ggagaccttc tttttactgc taaaaatcca actataatag cagaaataga
      901 tagtttaaaa tcacaactta gtcaatacaa aaaacaaaaa atatcacttt ctgatattgc
      961 tgaaaataaa gatgctattg cttctataaa tgcacagata actgctttaa gctcccagat
     1021 agcttctctg gataaaaaag cttatgacag agttactgct ccttttgatg gcacagtata
     1081 cttgaatgac caaactggaa atccagacca accagtttca tttatgacta ttcaaggtct
     1141 agagttttat atgaaaggac aagcaagtga acaagattta cctaaaatga agattgacca
     1201 aatggtcaat atactagttt tttcaactga ccaaaagctt actggtagaa taagttttat
     1261 atctgataaa ccatctactc caaatactga aatgggagct cagcagaata cactatctta
     1321 ttatgatata aacatagcat ttgataatca agaaggatta gtaaatggat tccatcttca
     1381 agcatcactt gaagtagcta attcaagctt taaaatacca gcatcttgtg tacttaaaga
     1441 caacaaacac tcatatgtat ttaaggattt agatggtata ttgaaaaagc aaattgtaga
     1501 tgtagcaagt caaaatgatg attttgctgt agttagaggc ggtcttgaac aaggcgatat
     1561 aataataaaa caccctacta aagaaatgaa agaaggagac ccagttcaag gcgatggcgt
     1621 aactgctggt tctaataatg gagatactac tccaaacaaa aaagtagaag aagttactat
     1681 ggatgtgaat taatttacat atgttaatta aattagaaaa tattcaaaaa tattacaaag
     1741 tagggaaaga tgaattacat gttttaaaat ccttaaattt agaaattgaa tctggagaat
     1801 ttgtcatgat aatgggtaag tctggtagtg gtaaaactac tttacttaat atcttaggtt
     1861 ttctagatgt atttgatgaa ggaagatata tatttgatgg aacagatgta actaatttga
     1921 gtgaaaatga acgttctgtt tttagaaata ttaatattgg atttgttttc caacaattta
     1981 atttaataga aactctaaat gtatatcaaa atgtagagtt gcctctaatt tacaataaag
     2041 cactaaaaaa atctaataga gaagaaattg ttaaagataa attaagttct gttgggcttt
     2101 tggacaagct taagcagaaa ccacttcaat tatctggtgg tcaacaacag cgtgtagcca
     2161 ttgcacgttg cctagcaaat gaccctcaga taatctttgc tgacgaaccg actggggcat
     2221 tagatagtga aactagcaga gaaattatgg agcttttaac aaggctcaac aaacaaggta
     2281 agactataat aatggttaca catgatcaag atttaactaa gtatgcaact aaggttatac
     2341 gacttaaaga tggtgtgttt acttcggagg tgtaatcatg agtttattaa aaaattcttt
     2401 ggccaattta aaaggtcaca agcttcgtgt atttgtagct ttactctgga ttataatagg
     2461 aataacttca gtaatacttg ttagttctat aggtaatgga tttcaaaaag aaattaagaa
     2521 atctgtaaac aatgtaaacc ctaataaaac tactatttcg tttgaatcag ccgataacac
     2581 aggtcttact gatgatatga gtattttttt aaaaccattt aatgcaaaag atttagaaga
     2641 attatcattt gttgaaggag tagaaagaat agctccttca agagatgggt ttaaccttga
     2701 ttcagtttac tcttcacaag catcttttga taaaaaaact acgtatgttg atgttggacc
     2761 agtaaaaaaa gattctaaaa taaatttaat ttgtggtaga gatttttctt tagatgatga
     2821 aaaaagaaaa gtaattttac ttacattaca aagtacaagt gaaatttttg aaaatccaga
     2881 agatgcctta ggtcatggta tcaacataaa tggaactata tttgaaataa taggggtatt
     2941 agatgattct cagcaaaacc aagctggagg attctttgga ggttaccaag atatgcaatt
     3001 tactacttcc ctagtaccta aaaaggcttt tgacacttta atgagtcaaa attcttattc
     3061 aaatgaaatt taccagttag acttagtttc ttctaaaggc tataatgtaa atgaagttgc
     3121 aaacaatgtt atagctaaat tatatgagat gcaccctggt atcaatggtt cttatactac
     3181 accagaccca actgaacaga cagcttatct tgaaagcatt aattccaatg taaacaaata
     3241 tgtatctata ataactgtag ttgcaatgtt tgttggtggt attggtgtaa tgaatataat
     3301 gtatgtatct gttatggaaa gacaaagaga aattggtata agacgtgcta ttggagcaaa
     3361 acctaggtct atattatttc aatttttagt tgaagctgtt tttataacag tatgtggtgg
     3421 aattttagga actatagttg gatttactgc tactaactat gtttctaaat atataggttt
     3481 tgaagctata cctagcttaa atagcttatt ttatgcaatt gtagctacta tattgactgg
     3541 agttgtattt ggtctgattc cagcctttaa agcctctaaa ctagacccta taaaggcaat
     3601 ttataagtag aaattgtata aagattttcg atttttagat tagtttatat aaaacatact
     3661 taaatatata acgcactatt atatatgata gattaggaac ttaatctttc caaatataat
     3721 agtgcgttct ttcataaaaa ggattctctt ccttactata tctaaattac caagatgtta
     3781 tgttctaatt gttcaaacta atacttccaa ttttgattaa tcaatctcat tctcctaata
     3841 tacaatcttt tactttcaat cattgtacac tccgcctaaa aaaaataatc ttaaattagg
     3901 cgttatatac aatctcccca ttacatattg tataattaac ctttccatat aaagatttac
     3961 ctttaaatgg tgaattatca gctttagaaa caaagctttc aactgtccat tcttcttctg
     4021 gattgaatat aacaatgtct gctacagccc cttcttctat aaatccaata tttaaattgt
     4081 acaactttgc aggatttata gacatttttt ctattaactg catcatacta agatgatttt
     4141 tatgcaccaa atttgttatt ccaagagcta aagaagtttc aagcccaata attccacttg
     4201 gagcttttat aaactctcta tctttttctt ctttactatg aggtgcatgg tccgttgcta
     4261 ttatttcaat agtaccatca tttaatccct ctataatctt atctctgtcc catttacttc
     4321 ttagaggtgg attcattttt gcatttgttc caaactccaa tacatcttcc tcagtcaatg
     4381 taaagtgatg tggtgaagct tctgcaacta catttgcacc taagtatttt gcaaatctaa
     4441 ccatatcaac agatacacct gaacttatat gttgtatatc aactttagca ccagtcttta
     4501 gtgccaacat acaatctctg gctaccataa catcttctgc tacacttgat gcacctttta
     4561 atccaagttc tgaagctacc tttcctgcat ttacacctgg atttccaact aaagaagggt
     4621 cttcttcatg aaaactaagt ggtacatcca actcttttgc cttaatcatt gcctccataa
     4681 ttagattgct atccattaaa ggtaatccat catcagtaaa ccctggtaca ccagcttttt
     4741 taagagcttc catatcaact aactctttac cttcaaaacc tttagttata gctgctgctt
     4801 gtaaaacatt tatacatgca ttttttgact tttctttaac ataattaaaa gtatcttcat
     4861 tatctacaat aggattagta tttgccatac atataacagt tgtaaatcca cctctagcag
     4921 cagatttagc tccactttct atatcttctt tatatgtaaa cccagggtct ctaaagtgta
     4981 catgtacatc cactaaacct ggagcaacta cattaccact agcatctatt attttttcat
     5041 attcatcact ttcatcaaac ttgcctattt tataaatttt attttctttt ataattaagt
     5101 caatattctc atctctttga cttttagggt ctattactct accattttta attaaaatca
     5161 tattatttct cctttatatt tttaatttat atagactcat ataatattat acattatttt
     5221 acatacttaa atacaaaatt acgtttgaca tcaatagcct ttttaggaca aagttcatgg
     5281 caacagtaac atcttataca tttacttaag tctataatag cacccttagt ccctatctct
     5341 atagtggatg caggacaagc ttccttgcat tttccacatt ttatgcaatc ttgaaatctt
     5401 accacaggct ttggtgttat aagctttgaa ataggttcat ttaaaaattt tggtagcttt
     5461 acagaaaaca atcttaaatc cttacttaca tttggaatct tgtaattttt tataattaaa
     5521 tcttttatat cttcacctaa aatttcaata tctgaaaaat cttcttgtat atatcctctc
     5581 ttaatagcac ctctaattgt agcaactcta tttggaagta aacttataat cttacatgca
     5641 acaacatcta tagcatatgg attttgtgat gctaataaaa cgcctatttc tcgagtagta
     5701 ccagctgaag gtccatcacc ttccatacct actataccat ccataattgt caatgttggt
     5761 tttatataat cacaaatatc taaaagtaca ttttcgcaaa acaactcttc tgtaggaaat
     5821 ctataatgta tctctgcttt tttcaatcca gctatgcatc catataagtt ttttgtacca
     5881 ccagtaaaag ttgccattat atgagtcttt aatttacaaa gatttattat ataatctgaa
     5941 tctactattg gtttaataat atccatatat tttagaacat gtgctttttc actatgtatc
     6001 ttaacatctg aaacatcata atttaactta atgcccagtt catttgctac ttcttcaatt
     6061 ccagatgcct tataaatgct cttaagagaa ctttgattat atggaccacc agggctatct
     6121 gctattgtaa tatcacaatt taactctaaa agtttttcac atacaacttt tacaaccata
     6181 ggatgtgtag ttgtagcttc ttcaggcttt tttttcatta ataaatttgg ttttataagt
     6241 actttgcttc cttttttaac aaacttatct ataccaccaa tatcctctaa atttttttca
     6301 atagataact ttacttcttc ataattgtaa gttttacaac tcctaacaga taccgacttc
     6361 atattatctc catccttcta tcacaacagt ttatttgtat aatttaaaaa aggagaaacc
     6421 aaagtttctc cttttaatct atgttttaat tattattttc caaaatgtct gtttaataat
     6481 cctaagaatg ctttaccatg tctagcttcg tctttacaca tttcatgtac tgtatcatgt
     6541 atagcatcta atcctaattc tttagctctc ttagctaatt ttaattttcc atcagttgca
     6601 ccatactcag catcaactct aactcttaag ttttcttttg tatctgcaac tacaacttct
     6661 ccaagaagtt ctgcaaattt agcagcatgt tcagcctctt caaaagctat tctcttatac
     6721 gcttcagcta cttctggata accttctcta tcagcttgtc tactcattgc taaatacatt
     6781 cctacttctg tacactcacc agtaaagttg gctcttaatc cttcgattat ttctgcatct
     6841 acaccttgag ctactcctat tctatgttca tcagcccaaa ccatttcgcc tttcatttct
     6901 tcaaatttat cagctccaac tttacatact ggacattgtg ctggtgcagc atctccttca
     6961 tgtatatatc cacatactgt acaaacaaat tttttcataa ttaatttcct cccaatttta
     7021 tataattaaa tttttatttt taagtttaat aacttgctac aagaatatat ataccccaga
     7081 ctttatagct taaacactaa aaataaaatt tatttcctaa ttaattttat cactttgaaa
     7141 caccagtatc aaccaagttt tgatgtcaaa tttctacata atacataatt tatttgatta
     7201 attaggaaat agttgtcata ttaaatactt tctaatgaag actcctctga atctttaagt
     7261 ttcacttttt tgctctttaa aaaagataat ttagtttctg cagttatgat tgcaacaaat
     7321 atcaagatac taccaataac caattttgct gtaataagct cctttaaaat tattatagaa
     7381 aatattgtac caaatacagc ctctgtggat aatattatag ctgttctagt tccatcaact
     7441 cttttttgac atatagtctg aaataaaaat ccaattgtag tactaaatac agctagatac
     7501 atagttccca tgtaaccaga taattcagct tccatcttta attgacctgc aaatgtttga
     7561 actacaacag acattaaaaa cgctactgta aattgaatag ctgtcaatgc cattgggttg
     7621 ttatcttttg caaactcact tgtaaagaat atatgaaatg caaatccgaa tgaacatata
     7681 agtgttagaa aatctccaaa attaatagag aaatcagctt ctaaagaaag tatcccaatt
     7741 cctataagag ctaccaaact acttattatt cctattttat caagttttct tctataaagt
     7801 ataaatccta tgaatggaac tattacaaca ttagctgctg ttataaacgc atttttagat
     7861 ggtgtagtgt acataagtcc aatagtttgt actgtgaatg ctagaaataa aaatattcct
     7921 aaaatccctc ctgcttttaa taatttttta cccatattag cacgaatctg tttaaaaaac
     7981 agtaaattca taattatagc tgccaagaaa aatcttaaag ttatgatttg tagaggtgta
     8041 agcccaccgt ctaatgcaaa ttgggttgct acaaagccac ttccccatat aattgctata
     8101 aatattagtc ctatttctcc aaagtatttt ttcaataaag ccccctcctt tttatttttt
     8161 tgcaaaatta taaaccccct aaacagcaag agagtttttc tataagcatt actataaatt
     8221 aatatagtaa attttttcag tattttaaat ctaaatttac atacattttg agctcaaatt
     8281 tatatccact atttaacagt aatatattaa tcattttttg taaacacctt tttaataaat
     8341 ttttatattt tttatatttt tttacctata ctaaattttt ttatagatat ttttaatata
     8401 tatgatactt taatattatg caaataatgt catataagtt acactttagt tatcttagtt
     8461 acaactttgt cggtttactt tttctacttt cttcgatata attataatat atttttgata
     8521 caattcgaca aaagggggaa tgctgtaatt atggtaaaaa aaagaaaaaa gaaaactgtt
     8581 acacttacta tacttgttgt aatagttatt ggtatttttt ctatggcatg ggcggacatg
     8641 tctagaaaaa aagaaatgaa agaaactcaa gaaagactta aagctgaaag attagaaaaa
     8701 gaaagaattg aaaaagaaaa aaatgaacct attattggtg caaaaaaaga agctgtaaaa
     8761 gaatatggat atgacgcaaa aatagtttgg gacaaactta acaaatacga ctattcaaac
     8821 aatggagaaa agatagtctt tcttacattt gatgatggac catctactac taatactcca
     8881 caagttctag atatcttgaa aagacatggt gttagaggaa ctttctttat taagggtgat
     8941 tctcttgaaa gaaaaggagc taatgaaatt ttaaaaagaa catttgacga aggaaatgca
     9001 atagcccatc actcttatac tcatgactat aaaaaactat atcctaacag aagcctaaat
     9061 ctcgatacat tcgtaaatga acttaacaaa actgatgaag ctatgaaaaa agtcttagga
     9121 aagaattttt cctcaaatgt agttagatgc ccaggcgggt atatgtcatg gaaaaatatg
     9181 gaacctctag gaaactactt aaaagagaaa aacatggcat caattgattg gaacgcttta
     9241 aatgctgatg cagaaggtaa aaagaaaaat gcacaagaat tatttgaaca tgcaaagaaa
     9301 tcttctgaag gcaaagaaat ggttgttctt ttaatgcatg atacttatgg aaaacaagaa
     9361 acagtaaatg cattggacca aattataaca tattttaaag acaatggtta tcaatttaaa
     9421 attttaatat aataaaaaag caagtttatt gaatgtacat tttatactca atagacttgc
     9481 ttttacttta ctctatttta ctagctcgat ttttacaaat tttttctttc ctatttgaac
     9541 aactaattca ctctctttta caatagtgct taaatcctct actttttcac catttacctt
     9601 tactccacct tgagaagcta atcttctaac ttcactctta ctcttaacaa tctcattaga
     9661 aactagtact tcgattaagt caaatccatc ttccttaact tgaattgttt gtatatcttc
     9721 aggtatttga cctttttgga atacagattt aaatctttct tcagcttctt tagcagattc
     9781 ttctccatgg tataatgtta ctatttctct tgctaagttc atctttatat ctcttggatt
     9841 tactgaaccc tctttcaact gtgattctat tttattaact tcatcaggat gaacatctgt
     9901 cactaaattg tagtatttaa ttataagttc atcaggaatt tccatagatt tttggtacat
     9961 tattcccgct tcttcatcta ttccaatata gttacctaaa ctcttactca ttttttcttt
    10021 accatctaat ccttctatta aaggcatcat tattactatt tgagactcca taccaaattc
    10081 tctttgtaat gatcttccca ttagtaaatt gaatctttgg tcagttccac caagttctat
    10141 atcagcttct aatgctatag agtcatatgc ttgcattaat gggtagaaga actcatgtac
    10201 tgatattggc atttgtcctt catatctctt tttaaaatct tctctttcta acattctcgc
    10261 aacagtaata gttgctgcta attttattac atcttcaaaa tttaacttag ctaaccactc
    10321 gctattaaat cttacaatag ttttttcttt atctaaaact ttgaaaattt gttcttcata
    10381 agtttttgca tttgcaagaa cttgctctgt tgttaaagct tttctagctt tagattttcc
    10441 agttgggtct ccaatttttc ctgtaaaatc tccaattatt attactattt gatgacctaa
    10501 atcttgtaat tgtttcatct ttctaagaac tactgtatgc cctaaatgta tatctggagc
    10561 acttgggtct agacccaatt ttactatcat aggctttcct tctttttctg atttaataag
    10621 cttttccctt aactctttct catctattaa atcatctaca cctttcataa ttattcgcat
    10681 ttgctcgtct atcgatttca tttttcattc ctcctaaaat atttatataa tctataattt
    10741 ttatttttat aataaaaaaa gctttcatcc tcttaaaagg acgaaagcat tgcttacgtg
    10801 ttaccacctt agttcatcaa tatctcacga tattaatctc ttagagtaca attacatata
    10861 ctcgtgtact ataacgtgta ctaatccgat atctcttaat ggttgttatc tttcagagat
    10921 agtgctctga gatgtattca aactaaatca atttattcca tttcaccaaa ctggaactct
    10981 ctgttaaata aaatctagcc ctacttcttc tcttcatagc atttatatat tcagattatt
    11041 tcatcaatta caagaaattt ttcttaactt actcataata tattattatt tttatatttt
    11101 gtcaaccttt tttattatta tatacatgtt tttttacatt atactacttt tttatatttt
    11161 ttaccaatac ccaaaattta tttttcaatc aaaagattta tttgtttatt gactatatta
    11221 ctctgactca atcttatatt tattttctta tttaaaaatg cgtttataat tattaaacca
    11281 ataactgtta catcaaatat aaaaaacagc aataaaatta ttatcaaaaa taaaattcta
    11341 gcatataata attttctaaa cttagctatt ataaagtttt gtagtgacat acatgagtct
    11401 ctaatgataa aatagagact tatataggtt attgatataa agattgtttt taaataaaca
    11461 gaatcaactt taacattcaa cagttttaga acttcaaaaa tggctagata agaaacacat
    11521 atgtaaaaag ctttttttga gcaacataaa aattggttta aacttctaaa attcttaaat
    11581 attaaaaatt tttttagaga attagaatct aaaatatgca atttattccc taaaattaaa
    11641 cttaataaat atatgcaaaa caccatacca aaaggaaaca atgctatcat taaataataa
    11701 ataaaatttg tatacccatt aaaataaatc catttgctat atccttgaaa ttctttcata
    11761 aaactataac ctattaatgt tgaagcatat atatcaataa aaaccattac aataagccca
    11821 aatactgaac catatactaa atcatccata accattgtag gcttatttat tagatagcca
    11881 cacattatac caagtaatac actctgactt gcccaaatag cagttcctag atttccaagt
    11941 accagagaaa ttattaaaag cgaagtaatt ccagataaaa tggtatactt taaatcacat
    12001 ttcaagcaga ttatacaaaa aaatactggc actataaaat ctaagtaaat agcatatcca
    12061 aatccagtac tcacagctat aattgttact actatgaata aagatgacaa taaagctgct
    12121 tcagttaatt ttttagtagt attcaaaaca ctgcctccat aaatcataaa ttttctaact
    12181 aaagttttgt ttttaatata gtatatcact ttttaaaaat atttttaata aatataaatt
    12241 ttaataaagg tatttatgtt aaaaatggta taatgtatct taatattcag ttttttaaga
    12301 tgctaggagg taattactat gtttaaaatt aaacacttta atgatttgag tttagatgaa
    12361 ttttatgaaa tagcaaaatc aagatatgag gtatttgctt gtgaacagaa gatattttca
    12421 ttaaacgatt atgatgatat agataaaaac tcttatcaca tatttttaaa agaaaatgga
    12481 ttgatttgtg cttacgctag aataattcct aaagaataca gctcttataa tgatgtttcc
    12541 attggtagag ttttagttct ttctagtcat agaagaaaag gattagcaaa acaaatgatg
    12601 gattgtgcta tagattttat aaaagttaac ttacacgaaa ataatataac cttatcagca
    12661 caaacttata taaagaacct ttacttatct tgtggtttta aagaaatctc agaagtatac
    12721 gacgaagcag gtattgaaca tattaaaatg agattatagt gttgacaagc taatattgtt
    12781 aatatataat ttaagtataa attaaatatt gaattgatat ttaggtattt gaaaatacct
    12841 tacatagagt cagaaggctt ttgctttctg acttttttat tatcaaaatt caataattat
    12901 atggattcaa agtgttaatt tttattctat attctacttt ccccaaaagt aagaattata
    12961 cccaactttg tatgataggc atcttgccta tctttttttt gtaaaagtaa caaggtaata
    13021 atataatgca tagtttaaaa taagaagatt agcccaggct aaatttcaag catggaggtg
    13081 ctattatgaa aaaccttaac gatattcaag tgaaaaaaac tgtcaaagtt gaagatatat
    13141 tatctagtgg taatttaaga gaaagaatgt tagcgcttgg tcttactaga ggagctgtta
    13201 tagatgtagt tagaaaaggt ccaaaaaata atttaactgt ctataaaatc agaggtagca
    13261 agatagctct acgacaagaa gaaagtagct taatattagt ttctgacatt taaaaatttc
    13321 tagcaggagg atattaatat ggggttgaca cataactcaa ctaaaatgag ttctttaaaa
    13381 gacatgtttg atatagacaa taaggaagac cagtttgtaa ttgcattggc tggcaatcca
    13441 aatacaggta aaagtactgt atttaatcat cttacaggac ttagacagca tactggaaac
    13501 tggccaggaa aaactgtagc tacagctcgt ggtaatttta aatataaaaa taccgaatat
    13561 gcattaatag atttaccagg aacatattct ttatttgcct tatcacaaga agaaattgta
    13621 gctcgtgatt ttatatgttt tggtaatcca gatgcagtaa tagtagtatg tgatgctaca
    13681 tgtcttgaaa gaaatttaaa tttagtattt caagtgatgg aacttacaga taaagttatt
    13741 ttgtgtatta atttaataga tgaagctaga aaaaaaggca ttactattga taaaaaactt
    13801 ttagaggatt ctcttggtat tccagttatt ttaactgctg caagaaatgg ctctggtatg
    13861 gatgaactat tggatacttt aaatgatgta tcttttgaca aatataaatt aaataataaa
    13921 cctgttagat acaatgaaaa tatagagaat gtggtaaaat caattcaacc agaattggat
    13981 aatattatac caggtataaa ttctagatgg ttgggactta gacttattga tggcgatgaa
    14041 agtatatttg aatctatgag taattatata gacaaaaatt ctatagatgc tattaatgaa
    14101 gtaaagaaaa agattccaga caatataaat aaacagaaaa taagagatga gtttactaaa
    14161 atcaactatg attatgctaa aaaactgagt gatgagtgtt gttctaatgt tgctaaaaaa
    14221 tcaactgata gagaagaaaa agtagataaa atattaacat ctaaaatatt tgggcttcca
    14281 ataatgctct tattattagg tactatattg tggattacta tagaaggagc taactatcca
    14341 tccactttat tatctaattt attactcgga tttgagccaa gtatttcggg tatattaaat
    14401 agtattaatt gtccatcatg gttaaatgat atgttggttt taggattata cagaacatta
    14461 gcatgggtaa tctctgtaat gctacctcct atggcaatat tttttccatt atttacccta
    14521 cttgaggatt ttggatattt gccaagagtt gcatttaact tagaccacct atttaaaaaa
    14581 gcttgtgcac atggaaaaca gtgtttgact atgtgtatgg gatttggatg taatgcagct
    14641 ggagttattg gttgtaggat aattgactct ccaagggaaa gacttatagc tatacttaca
    14701 aacaactttg ttccttgtaa tggtcgtttt cctactttga tagctatatc tacaatattt
    14761 tttagctcag ttataaccaa ctctttcgta tcaagcgtag caactgcact ttgcataact
    14821 ttactgataa ttctaggtgt tataataaca ttgttggttt cttacactct ttctaagacg
    14881 ctattaaaag gagttccgtc tacatttaca ttagaacttc ctccttatag agttcctcaa
    14941 ataggaagaa ctttatatac ctctataata gatagaacaa tatttgtttt aggaagggct
    15001 gtaatggtag ccatacctgc tggtgtcata acttggatat ttgcaaatat atatatagga
    15061 gatttaagta tattatcaca tgttgcaaac tttttagacc ctttagctaa attaattggt
    15121 cttgatggtt ttatattact tgcttttatt cttggattcc cagcaaatga gatagttgta
    15181 cctatacttt taatggctta cctagcaact ggttctatga tagaattaga tagctttagt
    15241 gctttaggtc aagttcttag agaacatgga tggacttatt tgacagcttt aaatgttatg
    15301 ctgttcagtt tactgcattg gccttgtgca acaacacttt taacaataaa aaaagaaact
    15361 ggtagtttaa aatggactgc cttaggattc ttaatgccta ctatacttgc ttttgttgtt
    15421 tgttttttaa caactacagt ttacaattta tttatataat tagtattaac tgacagtaga
    15481 catatattag agaaaccatt taaaaattta tatactttat tataaagcat agagatatat
    15541 tcaatgataa gtaaaattac ttaacatttg aatatatctc tattttaatt cttatctgga
    15601 tacttggatt gaaatttcag tcatataatt atcttcatta ctttcacaaa aaaagtcaag
    15661 tatactctcc tcatacgaat ttccaacaat tttatattca ttttcatata tatatttttt
    15721 caatttttcg taagatttat atgaatcctc atattttcca atatgtttta tgcaagcata
    15781 cattccttct ggctttacat atagcttttt atcctttatt tttttatcta tcttcaaata
    15841 aaaacttgat atacttaaat agtccccatt ttttatattt tcattactta ctattactcc
    15901 caactcatat ccttgataca aatttttcga tttacaataa ttggtaaaat ctattaattc
    15961 catcataaaa tcactattac tcatattact caaatcgctt gatagaacta aatattcttc
    16021 aaactttttg gatatataaa tttcttcact attcatttta gaaattcctt caactgttat
    16081 atttattcta ttttgcatct tagaacttat ctttcttagt ttttttattt tttctcttat
    16141 ctttttttct tcttctttaa gcattttcac acaaagctgg ggagttctat tttgtatata
    16201 ctcttttatt tcctctaaac tcattcctat ttctcttaat gattgtaata tatcaagtgt
    16261 atcatattga taaactgagt aatatctata attattttta tctttatatt caggagaaaa
    16321 aatacctatt ttgtcataga aaattaatgt ctgcttagat ataccacaca atttagcaaa
    16381 ttcacctgtt gtaaaatact gtttttccaa gggttataca ctccttttct ttttgttgtc
    16441 tatatagtta ctatattctt tattatttac taaatcaagt agttattatt ttagaaaatc
    16501 aatatggttt tgattttaaa gcttaaatat cagttagatg tcagttataa atattttacc
    16561 ctttcccatc ataaaaaaga tatcccctct taacttttgg atggaatatt atatttatac
    16621 ttgttagagt gaaaattgta ataggtgcta caataagata tttaattaaa cataaagtta
    16681 attattgtaa taaaaaatct ttagataaat tagagttaaa gtacggaaat atagatagag
    16741 aaaaagctgt taaactagaa atattttatc agtatttaat agaacttgaa tatatagaaa
    16801 tgagtttatt aataagaaga ttagatactg caataacatc attagcatta gtatctatta
    16861 taacaatagc atcatattat ttaatcagaa aaaatgtgta attatgtaag ctatttataa
    16921 taaaacactg ataaaattaa taataaaaag gtaataggat ttctatacta cctttttgtt
    16981 tttataatat agtgtaattt tattatattt ttgtatgcta atgtaactag ataatcataa
    17041 gataacacat taaaagaaaa ttatgaaaac ttacattctg tatagttaat ataaaacata
    17101 agtaatataa atttatgtaa agcaacaaaa gatagattta cattccatat agttaatata
    17161 aaaccttaga gaaagcgaaa acgtaccatt aaaatcaaat atttacattc catatagtta
    17221 atataaaacg ttgtaatcat agttccaatt agccacttta acatgcattt acattccata
    17281 tagttaatat aaaacaccaa aataaactta gtattttcaa cacttacacg tatacaactc
    17341 tcctaaattt gcagtgaacg agcaatagtg caattgataa cgcttatcat gcactctcaa
    17401 cgccttatat ttcaactgtt acgccaaatt ttttcacaaa tatcgctcac tgcaaaattc
    17461 ctataatttt attatatcat aaatatatta cttttgaata ttgataccaa tttataccat
    17521 aataaaagca aaaaaacgta atctatctac attagattta aattctataa cttaaagttt
    17581 tttacataat atttatgctt gtttaatcaa tctaatatat cattcttgta tattgctttt
    17641 aatagtcttt tttcttaaat aaatatctat ctgaacaagc atagtttaat taaaaacttt
    17701 tgtattccct taaaactgta tctacctctt attattttat ttatgatata ttatttttaa
    17761 tctaaaaata gatatctatt tttattatgg ttatcccttt ttaaaatact ttaatcatat
    17821 actattccca atttaacatc cattgaaatg ctattttctt atattgcaat ttataattga
    17881 tatatcttca atataataat ttaatgtatt tttgatttta aagcttttca gtgatattat
    17941 tgataaatta gaattaatta tctagcttta aaaggtcaaa gatttctgtt gctgtctgcg
    18001 gttttccaaa taaatatcct tgtatgtaat ctggctttat ttgtttaact aaatcatact
    18061 cttcttgtgt ttctacacct tctaaacata cttttattcc tacatcatga caaattgcaa
    18121 caataaaatg tataaatgta gcatcaaact tactctttaa tatatcttta acaaatactc
    18181 tatcaatttt cactatatct attggagaaa attttaaaac ttctagagac gagtatccag
    18241 taccaaaatc atccatagca atataaattc ctaaatcttg taaagcctta aatttaaact
    18301 gtaaaatact catattttgt actgtatgac tttctgtcaa ttctaaaaca agattttgat
    18361 aaggaaaatt ttcatcatct ataattttta ctatatcttc aataaatgtg tcttctaata
    18421 tttgaacagc tgaaacgttt acactcactt taaaaaaagg atagtaatca atccatttcc
    18481 taaaagtacg taatgccatt cgaagcaccc aagcccctac aatatttatc atatcatttt
    18541 cttctaatat tggaataaat tccaaaggag aaattgcttt gcatttgtca ttagtccacc
    18601 ttaaaagaac ttctacacct attattttat gactttctgt atctacttgt ggctggaatc
    18661 gaagactaaa ccccctaaaa tcatcattaa ttgatgcctt taaatcccgc atcatttcta
    18721 atgaatacat tttatttttt aatatttctt gggagaaaaa aacaagcctg tttttaccat
    18781 gctctttcgc atattgtaaa gagtaactag cacacttata aagttctttt actgtatctc
    18841 catgttttgg atatattaca caaccagcag aaattgttat atttaatcca tattttctcc
    18901 atagttgaag gtgtataatc atattctgta tttgattata tagagttaga atttcatttt
    18961 cttcaacatt atcaacaaga atgcccattt cgtccccatc aagtttataa agttcagcat
    19021 tatctggtaa aatagattgt acagactgtg ctagtgtttt tattatatta tctccaaaat
    19081 ccctatcata catctcatta acatttttaa aatcgtcaat atctaataat actatgcata
    19141 atttttcaat cataggattt gaaattttat cttcaaatac actcataaat tcatgataat
    19201 tcagtaactg tgtcaatgaa tcaatcttat tttgtttacc taattgcgtc attattcctg
    19261 caaaaatact tggctctcca aattcatcac gcattagttg acctctacat cttaaccata
    19321 tatattctcc actacgattt ttagccctaa attccactgt atgataatcc atctggtttt
    19381 tacctatttc agtgtttgac ttataaaaac gattccagtc ttctggatgt acaatttttt
    19441 tccagtaaac aagcggattt ttaacaattt ctcctggtaa gtcaaataat tcaacttgtg
    19501 atggtgaata tcgaaatacg cctgttttca tattgcaaat gtatatatat tcatctgtac
    19561 ctctaatcaa agcatcgtaa agcaatgtag aattataatc aaaattgtct cttgaaaaat
    19621 taaaaactcc tttttcttct ttattatttg atatttcatg aaattcatta atcttaattg
    19681 gtttatttaa gcttgttgag tttgcaatat ctattgattg atgcatatga acaactgtgc
    19741 catcttgcca tgtaattaaa ctatcataat tttcaaaaac acgatttaac ttattacatt
    19801 tttcatacca ctttattaat actccttttt tatcattctt taataattct aaaactttac
    19861 aaaaactaca agtagaattt ttttcaggat ataatacttg ccaacaaact tttccttctg
    19921 gatctaaaat attatattct tctttcattt ttttgttcat aaaaataatt tcattagtat
    19981 gaatatttgt aacatatata ttaatctgta gttgatttaa tataacttca aaattatgtt
    20041 tgttcatata cttatctcct ccatagttac tgctctttat aacaacattg ttaaaattat
    20101 tctttttaga agatttactt ataacttata catatacact aaatacctta atttaattag
    20161 aaagtttatt acttcatatt ttaaattata attgataaaa aaaaatacag caatatagta
    20221 ttaccaattt aaaaaaaatt aata
//
LOCUS       DAYAOO010000074        19927 bp    DNA     linear   BCT 12-OCT-2024
DEFINITION  TPA_asm: Clostridioides difficile isolate ST8-SSI-h139-18
            SAMN40601845-rid21577343.denovo.074, whole genome shotgun sequence.
ACCESSION   DAYAOO010000074 DAYAOO010000000
VERSION     DAYAOO010000074.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN40601845
            Sequence Read Archive: SRR28438827
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 19927)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 19927)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-MAY-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-MAY-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002157583.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002157583.1
            Genome Coverage       :: 163x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/11/2024 16:19:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 4,038
            CDSs (total)                      :: 3,963
            Genes (coding)                    :: 3,930
            CDSs (with protein)               :: 3,930
            Genes (RNA)                       :: 75
            rRNAs                             :: 6, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 60
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 33
            CDSs (without protein)            :: 33
            Pseudo Genes (ambiguous residues) :: 0 of 33
            Pseudo Genes (frameshifted)       :: 7 of 33
            Pseudo Genes (incomplete)         :: 25 of 33
            Pseudo Genes (internal stop)      :: 11 of 33
            Pseudo Genes (multiple problems)  :: 8 of 33
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..19927
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN40601845-rid21577343.denovo.074"
                     /isolate="ST8-SSI-h139-18"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Denmark"
                     /collection_date="2018"
                     /collected_by="Statens Serum Institute"
     gene            <1..300
                     /gene="tcdR"
                     /locus_tag="ACGI5H_002905"
     CDS             <1..300
                     /gene="tcdR"
                     /locus_tag="ACGI5H_002905"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434528.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosylating toxin sigma factor TcdR"
                     /protein_id="HFG9698602.1"
                     /translation="LSRRYSKMKFNFVEFDENILNMKNNYQSKSIFEEDICFFGYILK
                     ELSGIQRKVIFYKYLKGYSDREISVKLKISRQAVNKAKNRAFKKIKKDYENYFNL"
     gene            618..7718
                     /gene="tcdB"
                     /locus_tag="ACGI5H_002906"
                     /gene_synonym="toxB"
     CDS             618..7718
                     /gene="tcdB"
                     /locus_tag="ACGI5H_002906"
                     /gene_synonym="toxB"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_074049122.1"
                     /note="Toxigenic strains produce this toxin (TcdB) or
                     TcdA. TcdB-producing strains are tumorigenic in mice;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosylating toxin TcdB"
                     /protein_id="HFG9698603.1"
                     /translation="MSLVNRKQLEKMANVRFRTQEDEYVAILDALEEYHNMSENTVVE
                     KYLKLKDINSLTDIYIDTYKKSGRNKALKKFKEYLVTEVLELKNNNLTPVEKNLHFVW
                     IGGQINDTAINYINQWKDVNSDYNVNVFYDSNAFLINTLKKTVVESAINDTLESFREN
                     LNDPRFDYNKFFRKRMEIIYDKQKNFINYYKAQREENPELIIDDIVKTYLSNEYSKEI
                     DELNTYIEESLNKITQNSGNDVRNFEEFKNGESFNLYEQELVERWNLAAASDILRISA
                     LKEIGGMYLDVDMLPGIQPDLFESIEKPSSVTVDFWEMTKLEAIMKYKEYIPEYTSEH
                     FDMLDEEVQSSFESVLASKSDKSEIFSSLGDMEASPLEVKIAFNSKGIINQGLISVKD
                     SYCSNLIVKQIENRYKILNNSLNPAISEDNDFNTTTNTFIDSIMAEANADNGRFMMEL
                     GKYLRVGFFPDVKTTINLSGPEAYAAAYQDLLMFKEGSMNIHLIEADLRNFEISKTNI
                     SQSTEQEMASLWSFDDARAKAQFEEYKRNYFEGSLGEDDNLDFSQNIVVDKEYLLEKI
                     SSLARSSERGYIHYIVQLQGDKISYEAACNLFAKTPYDSVLFQKNIEDSEIAYYYNPG
                     DGEIQEIDKYKIPSIISDRPKIKLTFIGHGKDEFNTDIFAGFDVDSLSTEIEAAIDLA
                     KEDISPKSIEINLLGCNMFSYSINVEETYPGKLLLKVKDKISELMPSISQDSIIVSAN
                     QYEVRINSEGRRELLDHSGEWINKEESIIKDISSKEYISFNPKENKITVKSKNLPELS
                     TLLQEIRNNSNSSDIELEEKVMLTECEINVISNIDTQIVEERIEEAKNLTSDSINYIK
                     DEFKLIESISDALCDLKQQNELEDSHFISFEDISETDEGFSIRFINKETGESIFVETE
                     KTIFSEYANHITEEISKIKGTIFDTVNGKLVKKVNLDTTHEVNTLNAAFFIQSLIEYN
                     SSKESLSNLSVAMKVQVYAQLFSTGLNTITDAAKVVELVSTALDETIDLLPTLSEGLP
                     IIATIIDGVSLGAAIKELSETSDPLLRQEIEAKIGIMAVNLTTATTAIITSSLGVASG
                     FSILLVPLAGISAGIPSLVNNELVLRDKATKVVDYFKHVSLVETEGVFTLLDDKIMMP
                     QDDLVISEIDFNNNSIVLGKCEIWRMEGGSGHTVTDDIDHFFSAPSITYREPHLSIYD
                     VLEVQKEELDLSKDLMVLPNAPNRVFAWETGWTPGLRSLENDGTKLLDRIRDNYEGEF
                     YWRYFAFIADALITTLKPRYEDTNIRINLDSNTRSFIVPIITTEYIREKLSYSFYGSG
                     GTYALSLSQYNMGINIELSESDVWIIDVDNVVRDVTIESDKIKKGDLIEGILSTLSIE
                     ENKIILNSHEINFSGEVNGSNGFVSLTFSILEGINAIIEVDLLSKSYKLLISGELKIL
                     MLNSNHIQQKIDYIGFNSELQKNIPYSFVDSEGKENGFINGSTKEGLFVSELPDVVLI
                     SKVYMDDSKPSFGYYSNNLKDVKVITKDNVNILTGYYLKDDIKISLSLTLQDEKTIKL
                     NSVHLDESGVAEILKFMNRKGNTNTSDSLMSFLESMNIKSIFVNFLQSNIKFILDANF
                     IISGTTSIGQFEFICDENDNIQPYFIKFNTLETNYTLYVGNRQNMIVEPNYDLDDSGD
                     ISSTVINFSQKYLYGIDSCVNKVVISPNIYTDEINITPVYETNNTYPEVIVLDANYIN
                     EKINVNINDLSIRYVWSNDGNDFILMSTSEENKVSQVKIRFVNVFKDKTLANKLSFNF
                     SDKQDVPVSEIILSFTPSYYEDGLIGYDLGLVSLYNEKFYINNFGMMVSGLIYINDSL
                     YYFKPPVNNLITGFVTVGDDKYYFNPINGGAASIGETIIDDKNYYFNQSGVLQTGVFS
                     TEDGFKYFAPANTLDENLEGEAIDFTGKLIIDENIYYFDDNYRGAVEWKELDGEMHYF
                     SPETGKAFKGLNQIGDYKYYFNSDGVMQKGFVSINDNKHYFDDSGVMKVGYTEIDGKH
                     FYFAENGEMQIGVFNTEDGFKYFAHHNEDLGNEEGEEISYSGILNFNNKIYYFDDSFT
                     AVVGWKDLEDGSKYYFDEDTAEAYIGLSLINDGQYYFNDDGIMQVGFVTINDKVFYFS
                     DSGIIESGVQNIDDNYFYIDDNGIVQIGVFDTSDGYKYFAPANTVNDNIYGQAVEYSG
                     LVRVGEDVYYFGETYTIETGWIYDMENESDKYYFNPETKKACKGINLIDDIKYYFDEK
                     GIMRTGLISFENNNYYFNENGEMQFGYINIEDKMFYFGEDGVMQIGVFNTPDGFKYFA
                     HQNTLDENFEGESINYTGWLDLDEKRYYFTDEYIAATGSVIIDGEEYYFDPDTAQLVI
                     SE"
     gene            7840..8340
                     /gene="tcdE"
                     /locus_tag="ACGI5H_002907"
     CDS             7840..8340
                     /gene="tcdE"
                     /locus_tag="ACGI5H_002907"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434540.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="holin-like glycosylating toxin export protein
                     TcdE"
                     /protein_id="HFG9698604.1"
                     /translation="MHSSSPFYISNGNKIFFYINLGGVMNMTISFLSEHIFIKLVILT
                     ISFDTLLGCLSAIKSRKFNSSFGIDGGIRKVAMIACIFFLSVVDILTKFNFLFMLPQD
                     CINFLRLKHLGISEFFSILFILYESVSILKNMCLCGLPVPKRLKEKIAILLDAMTDEM
                     NAKDEK"
     gene            8449..8580
                     /locus_tag="ACGI5H_002908"
     CDS             8449..8580
                     /locus_tag="ACGI5H_002908"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888444.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9698605.1"
                     /translation="MPRDTQVLNTYNFEASVHYYIDDKVVYQTLVHKDGAWSVGKIY"
     gene            8645..8851
                     /locus_tag="ACGI5H_002909"
     CDS             8645..8851
                     /locus_tag="ACGI5H_002909"
                     /inference="COORDINATES: protein motif:HMM:NF022413.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BhlA/UviB family holin-like peptide"
                     /protein_id="HFG9698606.1"
                     /translation="MKLFKNTKIRDEGQNDIENKYQTLINDLIDSLKVIGKIYKEIKT
                     LKKYKICLQITIRQSPYLIEESIN"
     gene            9068..17137
                     /gene="tcdA"
                     /locus_tag="ACGI5H_002910"
                     /gene_synonym="toxA"
     CDS             9068..17137
                     /gene="tcdA"
                     /locus_tag="ACGI5H_002910"
                     /gene_synonym="toxA"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_105161403.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosylating toxin TcdA"
                     /protein_id="HFG9698607.1"
                     /translation="MSLISKEELIKLAYSIRPRENEYKTILTNLDEYNKLTTNNNENK
                     YLQLKKLNESIDVFMNKYKTSSRNRALSNLKKDILKEVILIKNSNTSPVEKNLHFVWI
                     GGEVSDIALEYIKQWADINAEYNIKLWYDSEAFLVNTLKKAIVESSTTEALQLLEEEI
                     QNPQFDNMKFYKKRMEFIYDRQKRFINYYKSQINKPTVPTIDDIIKSHLVSEYNRDET
                     VLESYRTNSLRKINSNHGIDIRANSLFTEQELLNIYSQELLNRGNLAAASDIVRLLAL
                     KNFGGVYLDVDMLPGIHSDLFKTISRPSSIGLDRWEMIKLEAIMKYKKYINNYTSENF
                     DKLDQQLKDNFKLIIESKSEKSEIFSKLENLNVSDLEIKIAFALGSVINQALISKQGS
                     YLTNLVIEQVKNRYQFLNQHLNPAIESDNNFTDTTKIFHDSLFNSATAENSMFLTKIA
                     PYLQVGFMPEARSTISLSGPGAYASAYYDFINLQENTIEKTLKASDLIEFKFPENNLS
                     QLTEQEINSLWSFDQASAKYQFEKYVRDYTGGSLSEDNGVDFNKNTALDKNYLLNNKI
                     PSNNVEEAGSKNYVHYIIQLQGDDISYEATCNLFSKNPKNSIIIQRNMNESAKSYFLS
                     DDGESILELNKYRIPERLKNKEKVKVTFIGHGKDEFNTSEFARLSVDSLSNEISSFLD
                     TIKLDISPKNVEVNLLGCNMFSYDFNVEETYPGKLLLSIMDKITSTLPDVNKNSITIG
                     ANQYEVRINSEGRKELLAHSGKWINKEEAIMSDLSSKEYIFFDSIDNKLKAKSKNIPG
                     LASISEDIKTLLLDASVSPDTKFILNNLKLNIESSIGDYIYYEKLEPVKNIIHNSIDD
                     LIDEFNLLENVSDELYELKKLNNLDEKYLISFEDISKNNSTYSVRFINKSNGESVYVE
                     TEKEIFSKYSEHITKEISTIKNSIITDVNGNLLDNIQLDHTSQVNTLNAAFFIQSLID
                     YSSNKDVLNDLSTSVKVQLYAQLFSTGLNTIYDSIQLVNLISNAVNDTINVLPTITEG
                     IPIVSTILDGINLGAAIKELLDEHDPLLKKELEAKVGVLAINMSLSIAATVASIVGIG
                     AEVTIFLLPIAGISAGIPSLVNNELILHDKATSVVNYFNHLSESKKYGPLKTEDDKIL
                     VPIDDLVISEIDFNNNSIKLGTCNILAMEGGSGHTVTGNIDHFFSSPSISSHIPSLSI
                     YSAIGIETENLDFSKKIMMLPNAPSRVFWWETGAVPGLRSLENDGTRLLDSIRDLYPG
                     KFYWRFYAFFDYAITTLKPVYEDTNIKIKLDKDTRNFIMPTITTNEIRNKLSYSFDGA
                     GGTYSLLLSSYPISTNINLSKDDLWIFNIDNEVREISIENGTIKKGKLIKDVLSKIDI
                     NKNKLIIGNQTIDFSGDIDNKDRYIFLTCELDDKISLIIEINLVAKSYSLLLSGDKNY
                     LISNLSNTIEKINTLGLDSKNIAYNYTDESNNKYFGAISKTSQKSIIHYKKDSKNILE
                     FYNDSTLEFNSKDFIAEDINVFMKDDINTITGKYYVDNNTDKSIDFSISLVSKNQVKV
                     NGLYLNESVYSSYLDFVKNSDGHHNTSNFMNLFLDNISFWKLFGFENINFVIDKYFTL
                     VGKTNLGYVEFICDNNKNIDIYFGEWKTSSSKSTIFSGNGRNVVVEPIYNPDTGEDIS
                     TSLDFSYEPLYGIDRYINKVLIAPDLYTSLININTNYYSNEYYPEIIVLNPNTFHKKV
                     NINLDSSSFEYKWSTEGSDFILVRYLEESNKKILQKIRIKGILSNTQSFNKMSIDFKD
                     IKKLSLGYIMSNFKSFNSENELDRDHLGFKIIDNKTYYYDEDSKLVKGLININNSLFY
                     FDPIEFNLVTGWQTINGKKYYFDINTGAALTSYKIINGKHFYFNNDGVMQLGVFKGPD
                     GFEYFAPANTQNNNIEGQAIVYQSKFLTLNGKKYYFDNDSKAVTGWRIINNEKYYFNP
                     NNAIAAVGLQVIDNNKYYFNPDTAIISKGWQTVNGSRYYFDTDTAIAFNGYKTIDGKH
                     FYFDSDCVVKIGVFSTSNGFEYFAPANTYNNNIEGQAIVYQSKFLTLNGKKYYFDNNS
                     KAVTGWQTIDSKKYYFNTNTAEAATGWQTIDGKKYYFNTNTAEAATGWQTIDGKKYYF
                     NTNTAIASTGYTIINGKHFYFNTDGIMQIGVFKGPNGFEYFAPANTDANNIEGQAILY
                     QNEFLTLNGKKYYFGSDSKAVTGWRIINNKKYYFNPNNAIAAIHLCTINNDKYYFSYD
                     GILQNGYITIERNNFYFDANNESKMVTGVFKGPNGFEYFAPANTHNNNIEGQAIVYQN
                     KFLTLNGKKYYFDNDSKAVTGWQTIDGKKYYFNLNTAEAATGWQTIDGKKYYFNTNTF
                     IASTGYTSINGKHFYFNTDGIMQIGVFKGPNGFEYFAPANTHNNNIEGQAILYQNKFL
                     TLNGKKYYFGSDSKAVTGLRTIDGKKYYFNTNTAVAVTGWQTINGKKYYFNTNTSIAS
                     TGYTIISGKHFYFNTDGIMQIGVFKGPDGFEYFAPANTDANNIEGQAIRYQNRFLYLH
                     DNIYYFGNNSKAATGWVTIDGNRYYFEPNTAMGANGYKTIDNKNFYFRNGLPQIGVFK
                     GSNGFEYFAPANTDANNIEGQAIRYQNRFLHLLGKIYYFGNNSKAVTGWQTINGKVYY
                     FMPDTAMAAAGGLFEIDGVIYFFGVDGVKAPGIYG"
     gene            complement(17472..18170)
                     /gene="tcdC"
                     /locus_tag="ACGI5H_002911"
     CDS             complement(17472..18170)
                     /gene="tcdC"
                     /locus_tag="ACGI5H_002911"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860905.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosylating toxin anti-sigma factor TcdC"
                     /protein_id="HFG9698608.1"
                     /translation="MFSKKNEGNEFSNEGKGSSKKIIKFFKSTKGIALLAFILGVFFG
                     NISSPACSEDHEEVISNQTSVIDSQKTEIETLNSKLSDAEPWFKMKDDEKKAIEAENQ
                     RKAEEAKKAEEAKKAEEQRKKEEEEKKGYDTGITYDQLARTPDDYKYKKVKFEGKVIQ
                     VIEDGDEVQIRLAVSGNYDKVVLCSYKKSITPSRVLEDDYITIRGISAGTITYESTMG
                     GNITIPGIAVEKIN"
     gene            18596..18841
                     /gene="cdd1"
                     /locus_tag="ACGI5H_002912"
     CDS             18596..18841
                     /gene="cdd1"
                     /locus_tag="ACGI5H_002912"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888450.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein Cdd1"
                     /protein_id="HFG9698609.1"
                     /translation="MGELQKIPGVGKATEKSLIMLGYTTIKSLKDANPAQMYEKECLM
                     RGQHIDRCQLYVYRCAVYFASTENPEPEKLKWWYWKD"
     gene            complement(19059..19328)
                     /locus_tag="ACGI5H_002913"
     CDS             complement(19059..19328)
                     /locus_tag="ACGI5H_002913"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888452.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3795 domain-containing protein"
                     /protein_id="HFG9698610.1"
                     /translation="MFESRCGVCCDSCTKKEQVNCTGCPTMEKPFWGGECKVKTCCES
                     KELNHCGECDTFPCDMLLNKGKDQGFDPMVNIEQCRKWLEETVSN"
BASE COUNT         7892 a         2252 c         3024 g         6759 t
ORIGIN      
        1 ttgtctagaa gatattctaa aatgaagttt aattttgtag aatttgatga aaatatctta
       61 aatatgaaaa ataattatca aagtaagtct atttttgagg aagatatttg ttttttcgga
      121 tatattttga aagaattatc tggtattcaa agaaaagtta ttttttataa atatttaaaa
      181 ggatattctg atagagaaat atcagtgaaa ttaaaaatat ctagacaagc tgttaataag
      241 gctaaaaata gagcatttaa aaaaataaaa aaagactatg aaaattattt taacttgtaa
      301 ttaatgagtt taaagaaata tttacaatag aaatcaaatt ttataattaa ctttattgta
      361 aaattaataa cttaatctaa gaatatctta atttttatat tttatataga acaatgttta
      421 catatttatt tcagacaacg tctttattca atcgaagagc aaattaatca actgagtgtc
      481 ttaaatttaa aatgttagga agtgaatgta tatgaaaacc taagtagata ttagtatatt
      541 ttataaatag aaaggaggat atataaaaga gttttagcat ttagatgtaa aaatattata
      601 gtaaaggaga aaattttatg agtttagtta atagaaaaca gttagaaaaa atggcaaatg
      661 taagatttcg tactcaagaa gatgaatatg ttgcaatatt ggatgcttta gaagaatatc
      721 ataatatgtc agagaatact gtagtcgaaa aatatttaaa attaaaagat ataaatagtt
      781 taacagatat ttatatagat acatataaaa aatctggtag aaataaagcc ttaaaaaaat
      841 ttaaggaata tctagttaca gaagtattag agctaaagaa taataattta actccagttg
      901 agaaaaattt acattttgtt tggattggag gtcaaataaa tgacactgct attaattata
      961 taaatcaatg gaaagatgta aatagtgatt ataatgttaa tgttttttat gatagtaatg
     1021 catttttgat aaacacattg aaaaaaactg tagtagaatc agcaataaat gatacacttg
     1081 aatcatttag agaaaactta aatgacccta gatttgacta taataaattc ttcagaaaac
     1141 gtatggaaat aatttatgat aaacagaaaa atttcataaa ctactataaa gctcaaagag
     1201 aagaaaatcc tgaacttata attgatgata ttgtaaagac atatctttca aatgagtatt
     1261 caaaggagat agatgaactt aatacctata ttgaagaatc cttaaataaa attacacaga
     1321 atagtggaaa tgatgttaga aactttgaag aatttaaaaa tggagagtca ttcaacttat
     1381 atgaacaaga gttggtagaa aggtggaatt tagctgctgc ttctgacata ttaagaatat
     1441 ctgcattaaa agaaattggt ggtatgtatt tagatgttga tatgttacca ggaatacaac
     1501 cagacttatt tgagtctata gagaaaccta gttcagtaac agtggatttt tgggaaatga
     1561 caaagttaga agctataatg aaatacaaag aatatatacc agaatatacc tcagaacatt
     1621 ttgacatgtt agacgaagaa gttcaaagta gttttgaatc tgttctagct tctaagtcag
     1681 ataaatcaga aatattctca tcacttggtg atatggaggc atcaccacta gaagttaaaa
     1741 ttgcatttaa tagtaagggt attataaatc aagggctaat ttctgtgaaa gactcatatt
     1801 gtagcaattt aatagtaaaa caaatcgaga atagatataa aatattgaat aatagtttaa
     1861 atccagctat tagcgaggat aatgatttta atactacaac gaataccttt attgatagta
     1921 taatggctga agctaatgca gataatggta gatttatgat ggaactagga aagtatttaa
     1981 gagttggttt cttcccagat gttaaaacta ctattaactt aagtggccct gaagcatatg
     2041 cggcagctta tcaagattta ttaatgttta aagaaggcag tatgaatatc catttgatag
     2101 aagctgattt aagaaacttt gaaatctcta aaactaatat ttctcaatca actgaacaag
     2161 aaatggctag cttatggtca tttgacgatg caagagctaa agctcaattt gaagaatata
     2221 aaaggaatta ttttgaaggt tctcttggtg aagatgataa tcttgatttt tctcaaaata
     2281 tagtagttga caaggagtat cttttagaaa aaatatcttc attagcaaga agttcagaga
     2341 gaggatatat acactatatt gttcagttac aaggagataa aattagttat gaagcagcat
     2401 gtaacttatt tgcaaagact ccttatgata gtgtactatt tcagaaaaat atagaagatt
     2461 cagaaattgc atattattat aatcctggag atggtgaaat acaagaaata gacaagtata
     2521 aaattccaag tataatttct gatagaccta agattaaatt aacatttatt ggtcatggta
     2581 aagatgaatt taatactgat atatttgcag gttttgatgt agattcatta tccacagaaa
     2641 tagaagcagc aatagattta gctaaagagg atatttctcc taagtcaata gaaataaatt
     2701 tattaggatg taatatgttt agctactcta tcaacgtaga ggagacttat cctggaaaat
     2761 tattacttaa agttaaagat aaaatatcag aattaatgcc atctataagt caagactcta
     2821 ttatagtaag tgcaaatcaa tatgaagtta gaataaatag tgaaggaaga agagaattat
     2881 tggatcattc tggtgaatgg ataaataaag aagaaagtat tataaaggat atttcatcaa
     2941 aagaatatat atcatttaat cctaaagaaa ataaaattac agtaaaatct aaaaatttac
     3001 ctgagctatc tacattatta caagaaatta gaaataattc taattcaagt gatattgaac
     3061 tagaagaaaa agtaatgtta acagaatgtg agataaatgt tatttcaaat atagatacgc
     3121 aaattgttga ggaaaggatt gaagaagcta agaatttaac ttctgactct attaattata
     3181 taaaagatga atttaaacta atagaatcta tttctgatgc actatgtgac ttaaaacaac
     3241 agaatgaatt agaagattct cattttatat cttttgagga catatcagag actgatgagg
     3301 gatttagtat aagatttatt aataaagaaa ctggagaatc tatatttgta gaaactgaaa
     3361 aaacaatatt ctctgaatat gctaatcata taactgaaga gatttctaag ataaaaggta
     3421 ctatatttga tactgtaaat ggtaagttag taaaaaaagt aaatttagat actacacacg
     3481 aagtaaatac tttaaatgct gcatttttta tacaatcatt aatagaatat aatagttcta
     3541 aagaatctct tagtaattta agtgtagcaa tgaaagtcca agtttacgct caattattta
     3601 gtactggttt aaatactatt acagatgcag ccaaagttgt tgaattagta tcaactgcat
     3661 tagatgaaac tatagactta cttcctacat tatctgaagg attacctata attgcaacta
     3721 ttatagatgg tgtaagttta ggtgcagcaa tcaaagagct aagtgaaacg agtgacccat
     3781 tattaagaca agaaatagaa gctaagatag gtataatggc agtaaattta acaacagcta
     3841 caactgcaat cattacttca tctttggggg tagctagtgg atttagtata cttttagttc
     3901 ctttagcagg aatttcagca ggtataccaa gcttagtaaa caatgaactt gtacttcgag
     3961 ataaggcaac aaaggttgta gattatttta aacatgtttc attagttgaa actgaaggag
     4021 tatttacttt attagatgat aaaataatga tgccacaaga tgatttagtg atatcagaaa
     4081 tagattttaa taataattca atagttttag gtaaatgtga aatctggaga atggaaggtg
     4141 gttcaggtca tactgtaact gatgatatag atcacttctt ttcagcacca tcaataacat
     4201 atagagagcc acacttatct atatatgacg tattggaagt acaaaaagaa gaacttgatt
     4261 tgtcaaaaga tttaatggta ttacctaatg ctccaaatag agtatttgct tgggaaacag
     4321 gatggacacc aggtttaaga agcttagaaa atgatggcac aaaactgtta gaccgtataa
     4381 gagataacta tgaaggtgag ttttattgga gatattttgc ttttatagct gatgctttaa
     4441 taacaacatt aaaaccaaga tatgaagata ctaatataag aataaattta gatagtaata
     4501 ctagaagttt tatagttcca ataataacta cagaatatat aagagaaaaa ttatcatatt
     4561 ctttctatgg ttcaggagga acttatgcat tgtctctttc tcaatataat atgggtataa
     4621 atatagaatt aagtgaaagt gatgtttgga ttatagatgt tgataatgtt gtgagagatg
     4681 taactataga atctgataaa attaaaaaag gtgatttaat agaaggtatt ttatctacac
     4741 taagtattga agagaataaa attatcttaa atagccatga gattaatttt tctggtgagg
     4801 taaatggaag taatggattt gtttctttaa cattttcaat tttagaagga ataaatgcaa
     4861 ttatagaagt tgatttatta tctaaatcat ataaattact tatttctggc gaattaaaaa
     4921 tattgatgtt aaattcaaat catattcaac agaaaataga ttatatagga ttcaatagcg
     4981 aattacagaa aaatatacca tatagctttg tagatagtga aggaaaagag aatggtttta
     5041 ttaatggttc aacaaaagaa ggtttatttg tatctgaatt acctgatgta gttcttataa
     5101 gtaaggttta tatggatgat agtaagcctt catttggata ttatagtaat aatttgaaag
     5161 atgtcaaagt tataactaaa gataatgtta atatattaac aggttattat cttaaggatg
     5221 atataaaaat ctctctttct ttgactctac aagatgaaaa aactataaag ttaaatagtg
     5281 tgcatttaga tgaaagtgga gtagctgaga ttttgaagtt catgaataga aaaggtaata
     5341 caaatacttc agattcttta atgagctttt tagaaagtat gaatataaaa agtattttcg
     5401 ttaatttctt acaatctaat attaagttta tattagatgc taattttata ataagtggta
     5461 ctacttctat tggccaattt gagtttattt gtgatgaaaa tgataatata caaccatatt
     5521 tcattaagtt taatacacta gaaactaatt atactttata tgtaggaaat agacaaaata
     5581 tgatagtgga accaaattat gatttagatg attctggaga tatatcttca actgttatca
     5641 atttctctca aaagtatctt tatggaatag acagttgtgt taataaagtt gtaatttcac
     5701 caaatattta tacagatgaa ataaatataa cgcctgtata tgaaacaaat aatacttatc
     5761 cagaagttat tgtattagat gcaaattata taaatgaaaa aataaatgtt aatatcaatg
     5821 atctatctat acgatatgta tggagtaatg atggtaatga ttttattctt atgtcaacta
     5881 gtgaagaaaa taaggtgtca caagttaaaa taagattcgt taatgttttt aaagataaga
     5941 ctttggcaaa taagctatct tttaacttta gtgataaaca agatgtacct gtaagtgaaa
     6001 taatcttatc atttacacct tcatattatg aggatggatt gattggctat gatttgggtc
     6061 tagtttcttt atataatgag aaattttata ttaataactt tggaatgatg gtatctggat
     6121 taatatatat taatgattca ttatattatt ttaaaccacc agtaaataat ttgataactg
     6181 gatttgtgac tgtaggcgat gataaatact actttaatcc aattaatggt ggagctgctt
     6241 caattggaga gacaataatt gatgacaaaa attattattt caaccaaagt ggagtgttac
     6301 aaacaggtgt atttagtaca gaagatggat ttaaatattt tgccccagct aatacacttg
     6361 atgaaaacct agaaggagaa gcaattgatt ttactggaaa attaattatt gacgaaaata
     6421 tttattattt tgatgataat tatagaggag ctgtagaatg gaaagaatta gatggtgaaa
     6481 tgcactattt tagcccagaa acaggtaaag cttttaaagg tctaaatcaa ataggtgatt
     6541 ataaatacta tttcaattct gatggagtta tgcaaaaagg atttgttagt ataaatgata
     6601 ataaacacta ttttgatgat tctggtgtta tgaaagtagg ttacactgaa atagatggca
     6661 agcatttcta ctttgctgaa aacggagaaa tgcaaatagg agtatttaat acagaagatg
     6721 gatttaaata ttttgctcat cataatgaag atttaggaaa tgaagaaggt gaagaaatct
     6781 catattctgg tatattaaat ttcaataata aaatttacta ttttgatgat tcatttacag
     6841 ctgtagttgg atggaaagat ttagaggatg gttcaaagta ttattttgat gaagatacag
     6901 cagaagcata tataggtttg tcattaataa atgatggtca atattatttt aatgatgatg
     6961 gaattatgca agttggattt gtcactataa atgataaagt cttctacttc tctgactctg
     7021 gaattataga atctggagta caaaacatag atgacaatta tttctatata gatgataatg
     7081 gtatagttca aattggtgta tttgatactt cagatggata taaatatttt gcacctgcta
     7141 atactgtaaa tgataatatt tacggacaag cagttgaata tagtggttta gttagagttg
     7201 gggaagatgt atattatttt ggagaaacat atacaattga gactggatgg atatatgata
     7261 tggaaaatga aagtgataaa tattatttca atccagaaac taaaaaagca tgcaaaggta
     7321 ttaatttaat tgatgatata aaatattatt ttgatgagaa gggcataatg agaacgggtc
     7381 ttatatcatt tgaaaataat aattattact ttaatgagaa tggtgaaatg caatttggtt
     7441 atataaatat agaagataag atgttctatt ttggtgaaga tggtgtcatg cagattggag
     7501 tatttaatac accagatgga tttaaatact ttgcacatca aaatactttg gatgagaatt
     7561 ttgagggaga atcaataaac tatactggtt ggttagattt agatgaaaag agatattatt
     7621 ttacagatga atatattgca gcaactggtt cagttattat tgatggtgag gagtattatt
     7681 ttgatcctga tacagctcaa ttagtgatta gtgaatagat aaaaatatgt taaatatatc
     7741 ctcttatact taaatatata aaaataaaca aaatgataca ctacataaag tgttctatct
     7801 aatatgaaga tttaccaata aaaaggtgga ctatgatgaa tgcacagtag ttcacctttt
     7861 tatatttcta atggtaacaa aatatttttt tatataaacc taggaggcgt tatgaatatg
     7921 acaatatctt ttttatcaga gcatatattt ataaagttag taattttaac tatatcattt
     7981 gatacattat taggatgttt aagtgcaata aaaagtcgta aatttaattc tagttttgga
     8041 atagatggag gaatcagaaa agtagcaatg atagcatgta tatttttttt atcagtagtt
     8101 gacattctta caaagtttaa ctttttattt atgttaccac aagattgtat caatttttta
     8161 agactaaaac atcttggaat atctgaattt ttctctattt tatttatttt atatgaaagt
     8221 gtaagtatat taaaaaatat gtgcttatgt ggattaccag tacctaagag attaaaggaa
     8281 aaaatagcaa ttttactaga tgcaatgaca gatgaaatga atgctaagga tgaaaagtaa
     8341 gtaatggtag atataataaa gatattaaca aataaaaagt gttatccaaa taagaatagc
     8401 tgaaagttat cataattcat gaaactaata atgaaaacga gggagcagat gccaagagac
     8461 acacaagtat taaatacata taatttcgaa gcaagtgttc attactatat agatgacaag
     8521 gtagtatatc aaacattggt tcacaaagat ggtgcatggt cagttggtaa aatctattaa
     8581 gctacattag ttacagatat cacaaactat aatagttaaa catagaaata tgtgtaaatt
     8641 gtgattgaaa ttattcaaaa acacaaaaat acgtgatgaa ggacaaaatg atatagaaaa
     8701 taagtatcaa accttaataa atgatttaat tgatagttta aaagttatag gaaaaatata
     8761 taaagaaata aaaacattaa aaaaatataa gatatgttta caaattacta tcagacaatc
     8821 tccttatcta atagaagagt caattaacta attgagtatc tttaaattga aatgttagga
     8881 agtgatttaa atatgaaaac ttaaattata aaaaatcaat attaatttat ttttaaaaaa
     8941 tagaaaggag tgtataagat ttattttcaa agtttaaaaa caagaaaatc aatttaaatt
     9001 tcagaaggaa taaatgtggt tatagaagtg gatttattat caaaaataat aatactagga
     9061 ggtttttatg tctttaatat ctaaagaaga gttaataaaa ctcgcatata gcattagacc
     9121 aagagaaaat gagtataaaa ctatactaac taatttagac gaatataata agttaactac
     9181 aaacaataat gaaaataaat atttacaatt aaaaaaacta aatgaatcaa ttgatgtttt
     9241 tatgaataaa tataaaactt caagcagaaa tagagcactc tctaatctaa aaaaagatat
     9301 attaaaagaa gtaattctta ttaaaaattc caatacaagc cctgtagaaa aaaatttaca
     9361 ttttgtatgg ataggtggag aagtcagtga tattgctctt gaatacataa aacaatgggc
     9421 tgatattaat gcagaatata atattaaact gtggtatgat agtgaagcat tcttagtaaa
     9481 tacactaaaa aaggctatag ttgaatcttc taccactgaa gcattacagc tactagagga
     9541 agagattcaa aatcctcaat ttgataatat gaaattttac aaaaaaagga tggaatttat
     9601 atatgataga caaaaaaggt ttataaatta ttataaatct caaatcaata aacctacagt
     9661 acctacaata gatgatatta taaagtctca tctagtatct gaatataata gagatgaaac
     9721 tgtattagaa tcatatagaa caaattcttt gagaaaaata aatagtaatc atgggataga
     9781 tatcagggct aatagtttgt ttacagaaca agagttatta aatatttata gtcaggagtt
     9841 gttaaatcgt ggaaatttag ctgcagcatc tgacatagta agattattag ccctaaaaaa
     9901 ttttggcgga gtatatttag atgttgatat gcttccaggt attcactctg atttatttaa
     9961 aacaatatct agacctagct ctattggact agaccgttgg gaaatgataa aattagaggc
    10021 tattatgaag tataaaaaat atataaataa ttatacatca gaaaactttg ataaacttga
    10081 tcaacaatta aaagataatt ttaaactcat tatagaaagt aaaagtgaaa aatctgagat
    10141 attttctaaa ttagaaaatt taaatgtatc tgatcttgaa attaaaatag ctttcgcttt
    10201 aggcagtgtt ataaatcaag ccttgatatc aaaacaaggt tcatatctta ctaacctagt
    10261 aatagaacaa gtaaaaaata gatatcaatt tttaaaccaa caccttaacc cagccataga
    10321 gtctgataat aacttcacag atactactaa aatttttcat gattcattat ttaattcagc
    10381 taccgcagaa aactctatgt ttttaacaaa aatagcacca tacttacaag taggttttat
    10441 gccagaagct cgctccacaa taagtttaag tggtccagga gcttatgcgt cagcttacta
    10501 tgatttcata aatttacaag aaaatactat agaaaaaact ttaaaagcat cagatttaat
    10561 agaatttaaa ttcccagaaa ataatctatc tcaattgaca gaacaagaaa taaatagtct
    10621 atggagcttt gatcaagcaa gtgcaaaata tcaatttgag aaatatgtaa gagattatac
    10681 tggtggatct ctttctgaag acaatggggt agactttaat aaaaatactg ccctcgacaa
    10741 aaactattta ttaaataata aaattccatc aaacaatgta gaagaagctg gaagtaaaaa
    10801 ttatgttcat tatatcatac agttacaagg agatgatata agttatgaag caacatgcaa
    10861 tttattttct aaaaatccta aaaatagtat tattatacaa cgaaatatga atgaaagtgc
    10921 aaaaagctac tttttaagtg atgatggaga atctatttta gaattaaata aatataggat
    10981 acctgaaaga ttaaaaaata aggaaaaagt aaaagtaacc tttattggac atggtaaaga
    11041 tgaattcaac acaagcgaat ttgctagatt aagtgtagat tcactttcca atgagataag
    11101 ttcattttta gataccataa aattagatat atcacctaaa aatgtagaag taaacttact
    11161 tggatgtaat atgtttagtt atgattttaa tgttgaagaa acttatcctg ggaagttgct
    11221 attaagtatt atggacaaaa ttacttccac tttacctgat gtaaataaaa attctattac
    11281 tataggagca aatcaatatg aagtaagaat taatagtgag ggaagaaaag aacttctggc
    11341 tcactcaggt aaatggataa ataaagaaga agctattatg agcgatttat ctagtaaaga
    11401 atacattttt tttgattcta tagataataa gctaaaagca aagtccaaga atattccagg
    11461 attagcatca atatcagaag atataaaaac attattactt gatgcaagtg ttagtcctga
    11521 tacaaaattt attttaaata atcttaagct taatattgaa tcttctattg gtgattacat
    11581 ttattatgaa aaattagagc ctgttaaaaa tataattcac aattctatag atgatttaat
    11641 agatgagttc aatctacttg aaaatgtatc tgatgaatta tatgaattaa aaaaattaaa
    11701 taatctagat gagaagtatt taatatcttt tgaagatatc tcaaaaaata attcaactta
    11761 ctctgtaaga tttattaaca aaagtaatgg tgagtcagtt tatgtagaaa cagaaaaaga
    11821 aattttttca aaatatagcg aacatattac aaaagaaata agtactataa agaatagtat
    11881 aattacagat gttaatggta atttattgga taatatacag ttagatcata cttctcaagt
    11941 taatacatta aacgcagcat tctttattca atcattaata gattatagta gcaataaaga
    12001 tgtactgaat gatttaagta cctcagttaa ggttcaactt tatgctcaac tatttagtac
    12061 aggtttaaat actatatatg actctatcca attagtaaat ttaatatcaa atgcagtaaa
    12121 tgatactata aatgtactac ctacaataac agaggggata cctattgtat ctactatatt
    12181 agacggaata aacttaggtg cagcaattaa ggaattacta gacgaacatg acccattact
    12241 aaaaaaagaa ttagaagcta aggtgggtgt tttagcaata aatatgtcat tatctatagc
    12301 tgcaactgta gcttcaattg ttggaatagg tgctgaagtt actattttct tattacctat
    12361 agctggtata tctgcaggaa taccttcatt agttaataat gaattaatat tgcatgataa
    12421 ggcaacttca gtggtaaact attttaatca tttgtctgaa tctaaaaaat atggccctct
    12481 taaaacagaa gatgataaaa ttttagttcc tattgatgat ttagtaatat cagaaataga
    12541 ttttaataat aattcgataa aactaggaac atgtaatata ttagcaatgg aggggggatc
    12601 aggacacaca gtgactggta atatagatca ctttttctca tctccatcta taagttctca
    12661 tattccttca ttatcaattt attctgcaat aggtatagaa acagaaaatc tagatttttc
    12721 aaaaaaaata atgatgttac ctaatgctcc ttcaagagtg ttttggtggg aaactggagc
    12781 agttccaggt ttaagatcat tggaaaatga cggaactaga ttacttgatt caataagaga
    12841 tttataccca ggtaaatttt actggagatt ctatgctttt ttcgattatg caataactac
    12901 attaaaacca gtttatgaag acactaatat taaaattaaa ctagataaag atactagaaa
    12961 cttcataatg ccaactataa ctactaacga aattagaaac aaattatctt attcatttga
    13021 tggagcagga ggaacttact ctttattatt atcttcatat ccaatatcaa cgaatataaa
    13081 tttatctaaa gatgatttat ggatatttaa tattgataat gaagtaagag aaatatctat
    13141 agaaaatggt actattaaaa aaggaaagtt aataaaagat gttttaagta aaattgatat
    13201 aaataaaaat aaacttatta taggcaatca aacaatagat ttttcaggcg atatagataa
    13261 taaagataga tatatattct tgacttgtga gttagatgat aaaattagtt taataataga
    13321 aataaatctt gttgcaaaat cttatagttt gttattgtct ggggataaaa attatttgat
    13381 atccaattta tctaatacta ttgagaaaat caatacttta ggcctagata gtaaaaatat
    13441 agcgtacaat tacactgatg aatctaataa taaatatttt ggagctatat ctaaaacaag
    13501 tcaaaaaagc ataatacatt ataaaaaaga cagtaaaaat atattagaat tttataatga
    13561 cagtacatta gaatttaaca gtaaagattt tattgctgaa gatataaatg tatttatgaa
    13621 agatgatatt aatactataa caggaaaata ctatgttgat aataatactg ataaaagtat
    13681 agatttctct atttctttag ttagtaaaaa tcaagtaaaa gtaaatggat tatatttaaa
    13741 tgaatccgta tactcatctt accttgattt tgtgaaaaat tcagatggac accataatac
    13801 ttctaatttt atgaatttat ttttggacaa tataagtttc tggaaattgt ttgggtttga
    13861 aaatataaat tttgtaatcg ataaatactt tacccttgtt ggtaaaacta atcttggata
    13921 tgtagaattt atttgtgaca ataataaaaa tatagatata tattttggtg aatggaaaac
    13981 atcgtcatct aaaagcacta tatttagcgg aaatggtaga aatgttgtag tagagcctat
    14041 atataatcct gatacgggtg aagatatatc tacttcacta gatttttcct atgaacctct
    14101 ctatggaata gatagatata tcaataaagt attgatagca cctgatttat atacaagttt
    14161 aataaatatt aataccaatt attattcaaa tgagtactac cctgagatta tagttcttaa
    14221 cccaaataca ttccacaaaa aagtaaatat aaatttagat agttcttctt ttgagtataa
    14281 atggtctaca gaaggaagtg actttatttt agttagatac ttagaagaaa gtaataaaaa
    14341 aatattacaa aaaataagaa tcaaaggtat cttatctaat actcaatcat ttaataaaat
    14401 gagtatagat tttaaagata ttaaaaaact atcattagga tatataatga gtaattttaa
    14461 atcatttaat tctgaaaatg aattagatag agatcattta ggatttaaaa taatagataa
    14521 taaaacttat tactatgatg aagatagtaa attagttaaa ggattaatca atataaataa
    14581 ttcattattc tattttgatc ctatagaatt taacttagta actggatggc aaactatcaa
    14641 tggtaaaaaa tattattttg atataaatac tggagcagct ttaactagtt ataaaattat
    14701 taatggtaaa cacttttatt ttaataatga tggtgtgatg cagttgggag tatttaaagg
    14761 acctgatgga tttgaatatt ttgcacctgc caatactcaa aataataaca tagaaggtca
    14821 ggctatagtt tatcaaagta aattcttaac tttgaatggc aaaaaatatt attttgataa
    14881 tgactcaaaa gcagtcactg gatggagaat tattaacaat gagaaatatt actttaatcc
    14941 taataatgct attgctgcag tcggattgca agtaattgac aataataagt attatttcaa
    15001 tcctgacact gctatcatct caaaaggttg gcagactgtt aatggtagta gatactactt
    15061 tgatactgat accgctattg cctttaatgg ttataaaact attgatggta aacactttta
    15121 ttttgatagt gattgtgtag tgaaaatagg tgtgtttagt acctctaatg gatttgaata
    15181 ttttgcacct gctaatactt ataataataa catagaaggt caggctatag tttatcaaag
    15241 taaattctta actttgaatg gtaaaaaata ttactttgat aataactcaa aagcagttac
    15301 cggatggcaa actattgata gtaaaaaata ttactttaat actaacactg ctgaagcagc
    15361 tactggatgg caaactattg atggtaaaaa atattacttt aatactaaca ctgctgaagc
    15421 agctactgga tggcaaacta ttgatggtaa aaaatattac tttaatacta acactgctat
    15481 agcttcaact ggttatacaa ttattaatgg taaacatttt tattttaata ctgatggtat
    15541 tatgcagata ggagtgttta aaggacctaa tggatttgaa tattttgcac ctgctaatac
    15601 ggatgctaac aacatagaag gtcaagctat actttaccaa aatgaattct taactttgaa
    15661 tggtaaaaaa tattactttg gtagtgactc aaaagcagtt actggatgga gaattattaa
    15721 caataagaaa tattacttta atcctaataa tgctattgct gcaattcatc tatgcactat
    15781 aaataatgac aagtattact ttagttatga tggaattctt caaaatggat atattactat
    15841 tgaaagaaat aatttctatt ttgatgctaa taatgaatct aaaatggtaa caggagtatt
    15901 taaaggacct aatggatttg agtattttgc acctgctaat actcacaata ataacataga
    15961 aggtcaggct atagtttacc agaacaaatt cttaactttg aatggcaaaa aatattattt
    16021 tgataatgac tcaaaagcag ttactggatg gcaaaccatt gatggtaaaa aatattactt
    16081 taatcttaac actgctgaag cagctactgg atggcaaact attgatggta aaaaatatta
    16141 ctttaatact aacactttca tagcctcaac tggttataca agtattaatg gtaaacattt
    16201 ttattttaat actgatggta ttatgcagat aggagtgttt aaaggaccta atggatttga
    16261 atactttgca cctgctaata ctcataataa taacatagaa ggtcaagcta tactttacca
    16321 aaataaattc ttaactttga atggtaaaaa atattacttt ggtagtgact caaaagcagt
    16381 taccggattg cgaactattg atggtaaaaa atattacttt aatactaaca ctgctgttgc
    16441 agttactgga tggcaaacta ttaatggtaa aaaatactac tttaatacta acacttctat
    16501 agcttcaact ggttatacaa ttattagtgg taaacatttt tattttaata ctgatggtat
    16561 tatgcagata ggagtgttta aaggacctga tggatttgaa tactttgcac ctgctaatac
    16621 agatgctaac aatatagaag gtcaagctat acgttatcaa aatagattcc tatatttaca
    16681 tgacaatata tattattttg gtaataattc aaaagcggct actggttggg taactattga
    16741 tggtaataga tattacttcg agcctaatac agctatgggt gcgaatggtt ataaaactat
    16801 tgataataaa aatttttact ttagaaatgg tttacctcag ataggagtgt ttaaagggtc
    16861 taatggattt gaatactttg cacctgctaa tacggatgct aacaatatag aaggtcaagc
    16921 tatacgttat caaaatagat tcctacattt acttggaaaa atatattact ttggtaataa
    16981 ttcaaaagca gttactggat ggcaaactat taatggtaaa gtatattact ttatgcctga
    17041 tactgctatg gctgcagctg gtggactttt cgagattgat ggtgttatat atttctttgg
    17101 tgttgatgga gtaaaagccc ctgggatata tggctaaaat atatgtttga taaaaaatta
    17161 ttcctgtgct actaagaaat tatttttata taataaatat tgagatttaa ttaaaagtca
    17221 tgtgttattg taatacatga cttttagtta aaatttttct atcatttaat aatctattat
    17281 tcttgactat tttataataa aattcatata tggaaatatt aatactaaat aattaatagt
    17341 tgataaaaaa tagataatat gctaaaagca aaaactaatt tagagccttg taactgttta
    17401 tttgcaatta taaaaacatc tttaaacata ttgactataa tataaaatat taactataat
    17461 acaaaacaat attaattaat tttctctaca gctatccctg gtatagttat atttccaccc
    17521 atagttgatt cataagttat agttccagca cttatacctc ttatagttat gtaatcatcc
    17581 tctaatactc ttgaaggagt tattgatttt ttataactac atagtacaac cttatcataa
    17641 tttccagaca cagctaatct tatttgcacc tcatcaccat cttcaataac ttgaataacc
    17701 ttaccttcaa attttacctt tttgtactta taatcatcag gtgttctagc taattggtca
    17761 taagtaatac cagtatcata tcctttcttc tcctcttctt cttttttgcg ttgttcttca
    17821 gcctttttag cttcttcagc ttttttagct tcttcagctt tacgttgatt ttcagcttca
    17881 atagctttct tttcgtcgtc tttcattttg aaccatggtt cagcatcaga caatttgcta
    17941 tttaaagttt ctatttctgt tttttgagaa tctataactg atgtttggtt agaaatgacc
    18001 tcctcatggt cttcagaaca agctggtgag gatatattgc caaaaaacac gcctaaaata
    18061 aatgccagta gagcaatacc ctttgtgctc ttaaagaatt taattatttt cttagagctt
    18121 ccttttcctt cattactaaa ttcgttaccc tcattttttt tagaaaacat aatacaatct
    18181 cccttttatt agatatattt tattttaaaa gttaaaaact taaaataact agttgactaa
    18241 aaattatata ttcatatttt cctaaaatat atttccccta agcataattt tacaaaataa
    18301 agtaagaaga ttcaatatat tttgaaaaaa taagataaaa atgtcagatt ataatataat
    18361 tttcttgaag gtgaatttta tatattaaat taaacataaa gtattttatt tgtataaaac
    18421 tatattatga tgtaattaag tgactcagtg atttagaggt ggtaaaatat atatatatga
    18481 aagagcataa ataaattgat ataataaaaa attaaatatt aaatattaac tataataaaa
    18541 aaatatctgg taataggtat aatataaaaa gaatatacca gaaagaaggt gaagtatggg
    18601 agaactacaa aaaattccag gggtagggaa agcaacagaa aaatctttaa tcatgttagg
    18661 atatacaact attaaatcac ttaaagatgc aaacccagca caaatgtatg aaaaggaatg
    18721 tttaatgcgt ggacagcaca tagacagatg tcagttatat gtatacagat gtgcagtata
    18781 ttttgcatca actgaaaatc cagaaccaga aaaattaaag tggtggtatt ggaaagatta
    18841 aaaaatcaaa aaagttagac ataaaaaaga gttgaatatc cgttttaaat aataaaaact
    18901 aatactcaac tcttttttag tcgtaaattt tatgtaaatc tatttgtatg gctaaatata
    18961 cccatcaata aatgtataaa tatactaatc aacaaatgac taaacatact acctaacaaa
    19021 ggattaaata aattccttaa caaagcattc taaaacaatt aattagaaac tgtttcttca
    19081 agccattttc tacattgctc aatatttacc atagggtcaa aaccttggtc ttttccctta
    19141 tttaaaagca tatcacaagg gaaagtatca cattcaccac aatgattaag ttccttactt
    19201 tcacagcaag ttttaacctt acattctcca ccccaaaatg gtttttccat agttgggcaa
    19261 ccagtgcaat ttacttgttc tttttttgta caactgtcac aacagacacc acatcttgat
    19321 tcaaacatat tcaaacatcc tttccattat ttaaaaatat tataaaatga ttttagatga
    19381 atacaaaagt gcaaatagtt gattttaggt catctaaatg ttaaacataa aattattagt
    19441 actggtaaat ttataaaaac tattccaaaa atctttttga atatttcaaa acacaataaa
    19501 ttacttcaaa tccccttgaa tatattttac agcattatag attgctttaa atctctttga
    19561 atattctaca agactataga ttagtttaaa tccctttgaa tatattttac aacattatag
    19621 attgttttaa atctctttga atattctaca agactataga ttagtttaaa tccctttgaa
    19681 tatttcaaaa caccatagat tactttaaat ccctttgaat gttctataac actataaatt
    19741 acttttaact tttatataac cataaagttt ttatctggca ctttaaatgg agttttatat
    19801 caaatttgcc ttccatcgaa taaccaaact taatttaatt acacattcca agagtcaaat
    19861 attcattcaa tatatttgat aattctatgt tatagctata attaaatata gattattaaa
    19921 gttaaat
//
LOCUS       DAYAOO010000075        19890 bp    DNA     linear   BCT 12-OCT-2024
DEFINITION  TPA_asm: Clostridioides difficile isolate ST8-SSI-h139-18
            SAMN40601845-rid21577343.denovo.075, whole genome shotgun sequence.
ACCESSION   DAYAOO010000075 DAYAOO010000000
VERSION     DAYAOO010000075.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN40601845
            Sequence Read Archive: SRR28438827
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 19890)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 19890)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-MAY-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-MAY-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002157583.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002157583.1
            Genome Coverage       :: 163x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/11/2024 16:19:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 4,038
            CDSs (total)                      :: 3,963
            Genes (coding)                    :: 3,930
            CDSs (with protein)               :: 3,930
            Genes (RNA)                       :: 75
            rRNAs                             :: 6, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 60
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 33
            CDSs (without protein)            :: 33
            Pseudo Genes (ambiguous residues) :: 0 of 33
            Pseudo Genes (frameshifted)       :: 7 of 33
            Pseudo Genes (incomplete)         :: 25 of 33
            Pseudo Genes (internal stop)      :: 11 of 33
            Pseudo Genes (multiple problems)  :: 8 of 33
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..19890
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN40601845-rid21577343.denovo.075"
                     /isolate="ST8-SSI-h139-18"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Denmark"
                     /collection_date="2018"
                     /collected_by="Statens Serum Institute"
     gene            complement(109..795)
                     /locus_tag="ACGI5H_002914"
     CDS             complement(109..795)
                     /locus_tag="ACGI5H_002914"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF554 domain-containing protein"
                     /protein_id="HFG9698611.1"
                     /translation="MFGVIANSLAIAGGCIVGLIIKGGLPQRVSDTIMNGIALCVLYI
                     GISGALEGKNTLVTIISVAVGALIGELIDIDKWVNKLGAFLQSKFSKGNKKDSIAEGF
                     ISSSLLFCIGAMAVVGSLESGLTGSHDTLFVKSVIDGIASIIFTASLGIGVMFSAISV
                     FLYEGIICVGASFLNGFLSDPVVTEMTAAGSLLIIGLGLNVLKLTNIKVANLLPAIFI
                     PILFGVFGII"
     gene            complement(844..1377)
                     /locus_tag="ACGI5H_002915"
     CDS             complement(844..1377)
                     /locus_tag="ACGI5H_002915"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prolyl-tRNA synthetase associated
                     domain-containing protein"
                     /protein_id="HFG9698612.1"
                     /translation="MSDLNNKKEQDENESSMNETKIYDILDKLNVEYDVVEHEAVYTA
                     EQLVILDGITKGCQCKNLFLRNAKGNKYYLIVVKGEKQVDLNSLKDKIGSSRLSFASP
                     ERLYNVLKLLPGSVNPFSLINDTERKVELYIDKDVIKEDYLNFHPNINTKTVNISRKG
                     FEEFLEYLKYPIQSIDV"
     gene            complement(1421..2053)
                     /locus_tag="ACGI5H_002916"
     CDS             complement(1421..2053)
                     /locus_tag="ACGI5H_002916"
                     /EC_number="3.5.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428771.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016812 - hydrolase activity, acting on
                     carbon-nitrogen (but not peptide) bonds, in cyclic amides
                     [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cyclase family protein"
                     /protein_id="HFG9698613.1"
                     /translation="MKVFDLTHVTHNDMPVYAEPNRPDIKKVAIIEENGYQETLISVF
                     SHNGTHMDSPRHMYTKGETLDKLDIENFVGKAYVLELEKGNENIELEYLKKYEDEIKN
                     SDFIIFKSGWSKFWDKKQYYVGYPTLTKEAANYIANTNIKGIGIDMLSVDRYDTSVFE
                     VHHILFEKGKIIIENLTNLENVPEKFLFIAAPFKYNDADGAPVRAIAIVE"
     gene            complement(2143..3222)
                     /locus_tag="ACGI5H_002917"
     CDS             complement(2143..3222)
                     /locus_tag="ACGI5H_002917"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435274.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SIR2 family protein"
                     /protein_id="HFG9698614.1"
                     /translation="MKIAIFLGAGASAAENLPIQNELFSEYFKKLNPTNYNTKMNREL
                     YIFFKQMFNIDIVKDNIDNANFPTFEEVLGLLDLAEQRKEAFRNFGLENLNNRSDSIR
                     FLRQYLILLMAEAIHNTPRTDNKYHKLLVENLLENDLLLDTTFISANYDIHIDNTVTG
                     LRDKNDLPIMLDYGVEFTNFKEELNWRKPKEPLIKLYKIHGSLNWLYCPICNSVTLTP
                     HEGGVMKLIENSSETKCLECGELTEPIIVPPTYFKNMSNIFLSDVWNETEKTLRDTDL
                     LIFCGYSFPEADMHIKYMLKRVQTNRKKPPLKIMVFNNHSQKQRITLKKEEGRYKRFL
                     GEDVIFTDNSFQDFSVNPLRFIKNI"
     gene            complement(3355..4701)
                     /gene="pepV"
                     /locus_tag="ACGI5H_002918"
     CDS             complement(3355..4701)
                     /gene="pepV"
                     /locus_tag="ACGI5H_002918"
                     /EC_number="3.4.13.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861407.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA];
                     GO_function: GO:0016805 - dipeptidase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="dipeptidase PepV"
                     /protein_id="HFG9698615.1"
                     /translation="MKEQIKEKVNSLQDEMISSIQESVKIPSVISEATENCPFGENVD
                     KALRGILDLCKSLGFKTVYKDGYYGYAEIGQGEKMIGILGHVDVVPEGDLESWNYPPF
                     EAVLEDGKLYGRGTQDDKGPTISAIYAVKALMDLNVDFNKRIRFIFGADEENLWRCIN
                     KYKENNEEIPNYGFTPDSRFPITNAEKGLLQVHLTCDSKSDIELSVGKALNAVPGKAI
                     YIGKYSDKLKKELNKLNFEYTVEGNKICIIGKSVHSAASDTGINAVARLCIALNNIGI
                     DSNIIKFLAEVIGEDANGNNIIPNCKDDVSGKLTVNIGRVTIDNEKEFAGIDVRIPVT
                     YKKDDFVKELKKMTDKYNLNYEEYDFLDSIYVPEDTLLVKTLRKVYEEETGLDGTPLS
                     SGGATYARALDNCVAFGAIFPGKPETEHQANEYLIVEDIIKATQIYALSIYELLKI"
     gene            complement(4770..6050)
                     /locus_tag="ACGI5H_002919"
     CDS             complement(4770..6050)
                     /locus_tag="ACGI5H_002919"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428777.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminotransferase class I/II-fold pyridoxal
                     phosphate-dependent enzyme"
                     /protein_id="HFG9698616.1"
                     /translation="MLNETKELLKDYYGIDDDTFKLSQEIMEEIKDKFEEIKEIREYN
                     QYKVLKAMQESKLSDMHFNWTTGYGYNDIGREKIEEIYSKVFNTEDALVRPIIVNGTH
                     ALTLCIQGIVRPGDEILSVTGRPYDTLEGVIGIREEKGSLKEYGVTYDDVDFLEDGNL
                     DLEGIKNKINDRTKLVMIQRSKGYSWRKSLSISDIKEAIEVIKSVKPEAIVMVDNCYG
                     EFLDTKEPTDVGADVMAGSLIKNPGGGLALTGGYIAGRKDLIELISYRMTSPGIGKEC
                     GLTFGTTRNVLQGFFLAPYIVSQAVMGAIFCSRAFEKLGYDVLPKYDDLRSDIIQCIR
                     LNNADEVISFCEGIQEAAPVDSYVKPVPWDMPGYESEVIMAAGAFIQGSSIELSADAP
                     IRPPYNVYFQGGLTFDHSKMGTLKAIEFIKKLKK"
     gene            complement(6177..6437)
                     /gene="hfq"
                     /locus_tag="ACGI5H_002920"
     CDS             complement(6177..6437)
                     /gene="hfq"
                     /locus_tag="ACGI5H_002920"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="RNA chaperone Hfq"
                     /protein_id="HFG9698617.1"
                     /translation="MKNTVLNLQDLFLNNARKERIPVTIYLVNGVQVKGLVKGFDSYI
                     ILIEGDNRQQNMIYKHAVSTIQPGKYINLTNQNQNNNNNNNR"
     gene            complement(6551..7486)
                     /gene="miaA"
                     /locus_tag="ACGI5H_002921"
     CDS             complement(6551..7486)
                     /gene="miaA"
                     /locus_tag="ACGI5H_002921"
                     /EC_number="2.5.1.75"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861408.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0052381 - tRNA dimethylallyltransferase
                     activity [Evidence IEA];
                     GO_process: GO:0006400 - tRNA modification [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (adenosine(37)-N6)-dimethylallyltransferase
                     MiaA"
                     /protein_id="HFG9698618.1"
                     /translation="MKKIPLIILTGPTAVGKTDLSIKLAKDMNAEIISADSMQIYEYM
                     DIGSAKVTEEEMQGVKHYLIDEVKPDYPFSVSEFQQRAKKYIHEINKKEKCVLVTGGT
                     GLYLNSLIYNMDFAQSDANNELREELQKQLAEKGIDYMHNKLKELDEESANRIHKNNT
                     KRVIRALEVCLSGKKMNDFSSDLKFNEEYQPIIIVLNRDREHLYQRINMRVDIMLKNG
                     LVEEVKKLLSMGFKKDMISMQGIGYKEILKYLDGEYTYEEAIEIIKRDSRRYAKRQIT
                     WFKRYKTAKWFDLDQYENIDELKNEIILYIKDSIK"
     gene            complement(7524..9491)
                     /gene="mutL"
                     /locus_tag="ACGI5H_002922"
     CDS             complement(7524..9491)
                     /gene="mutL"
                     /locus_tag="ACGI5H_002922"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729024.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0030983 - mismatched DNA binding [Evidence
                     IEA];
                     GO_process: GO:0006298 - mismatch repair [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA mismatch repair endonuclease MutL"
                     /protein_id="HFG9698619.1"
                     /translation="MKNIINILDDLTINKIAAGEVVERPSSVVKELIENSIDAGANKI
                     SIDIIDGGKSLIKITDNGIGIPSSEVEKSFLRHATSKIKKIDDLYDLYSLGFRGEALA
                     SISAVSKLEMTTKTKDEIIGTKIYVEGGKIISKEPIGSTNGTTIIIKDIFFNTPARQK
                     FLKSTHAETINISDLINKLAIGNPNIQFKYTNNNKQMLNTPGDGKLVNTIRSIYGKEI
                     TENIIDVEFKCNHFKMNGYIGNNNIYRSNKNLQHIYINKRFVKSKIIIDAITESYKSI
                     IPIGKHAVCFLNIEVDPSCIDVNIHPNKLEIKFEKEQEVYIELRDFLKVKLIHSNLIG
                     KYATYSDKKTQPRIAINSREKSTDYKLRNNDLLESTPKNSNITKGKDEVIEVVTLSSE
                     KPINEFQSVSEVLNASVEDDVKNINYLSEDSANDNIQEEFQVDGIKNEGNYYLGDSIK
                     DSEEEYLCSSKRKFSLYGYSVIGVVFNTYIILSKDDSMYLLDQHAAHERILYERYMEK
                     FYRQDINMQILLDPVVIEVSNVDMLQIENNLELFMKFGFELEIFGNNHIMVRCVPTIF
                     GVPETEKFILQIIDNIEEITSNYDLKGERFASMACRSAIKANDKIYDIEIKSLLEQLE
                     KCENPFTCPHGRPIMVEISKTEIEKMFKRIM"
     gene            complement(9502..12345)
                     /gene="mutS"
                     /locus_tag="ACGI5H_002923"
     CDS             complement(9502..12345)
                     /gene="mutS"
                     /locus_tag="ACGI5H_002923"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435264.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0030983 - mismatched DNA binding [Evidence
                     IEA];
                     GO_process: GO:0006298 - mismatch repair [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA mismatch repair protein MutS"
                     /protein_id="HFG9698620.1"
                     /translation="MQIDMNKLTPMMKQYLEVKNRYKDCILFFRLGDFYEMFFEDALV
                     ASKALEIALTGKACGLEERAPMCGVPFHSANSYISKLVENGYKVAIGEQMEDPSTAKG
                     IVRREVIRVITPGTVLDGNLLENKKNNYLLSLYKDGTNIGLTYVDISTGETNATCLNE
                     DKVIEEIAKIHPTEIIINDLDFIENLRDIATVSNIYINESFSDNYLDINILKEYFPDV
                     YLQKLKFDDKGLIKSSLSILLNYIYNTQKQITSNINNINIYNSSEYMVLDMFTRTNLE
                     LTQTIRGNKKKGSLLHVLDKTSTAMGGRLLRKYVEEPLINKSKIENRLDVIEEIKDDF
                     ILREDLNDILKNIYDIERICGKIAFERVTPKELIHLKNSIEKLPNLKDTINLSNAKIL
                     KEYVSEMDKLDDIYNLIDEAILEEPTITIKDGNIIKSDFSDELKELREISKNGAFLVK
                     EIENREREKTGVKSLKIGFNKVFGYYIEITKANFKQAKLDETYIRKQTLSNAERYITP
                     ELKEIEEKILHAEEKIKSLEYEIFVEIRDTIYKNIDRIQKVAKTIANIDVFVSLATVA
                     HINNYVKPAINENNKLDIRNGRHPVVENIVGEENFVPNDTYLNRGENIINIITGPNMS
                     GKSTYMRQTAIIALMAHIGSFVPAESADIPILDRIFTRVGASDDLSQGQSTFMVEMNE
                     VSLILKNATERSLVILDEIGRGTSTYDGISLAWSIVEYIQKNIRCKTLFATHYHELTD
                     LEEEFKEVKNYSIAVKEDGEGIIFLRKIIPQGADKSYGIYVAKLAKLPDEVIERAKYI
                     LKDLEKNHVYNSVAINGDKENNNIINSNLDEELVKVNQSNFKNKYESLKIEHELIVKD
                     YKHIKKDYDKLNSKFKALNDEVALIKQNDDKEKINQVDSVKEVALTQISFDSVNRDIL
                     SEEILNLDILNMTPLDAINSLYNLQRKAKEIKS"
     gene            complement(12505..13239)
                     /locus_tag="ACGI5H_002924"
     CDS             complement(12505..13239)
                     /locus_tag="ACGI5H_002924"
                     /EC_number="7.6.2.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428791.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HFG9698621.1"
                     /translation="MLTQMNFYHNKKVKVSIENVSKTYKDIEVLKDISIDVYEGEFVS
                     ILGPSGCGKSTIFNIITKLTDYDSGKVNINGKYSYMYQKDLLLPYKTIIDNVSLPLIL
                     KKEKKSKARSMVKPYFEVFGLSGYEDKYPSELSGGMRQRANFLRTFINSNDIMLLDEP
                     FGALDSLTKTSMQKWLLDVKKKVNSTILLITHDIDEAIMLSNRIYVISKKPSIVKKEF
                     VIDSRKLNEDNLENIIKLKKEIISLL"
     gene            complement(13208..14221)
                     /locus_tag="ACGI5H_002925"
     CDS             complement(13208..14221)
                     /locus_tag="ACGI5H_002925"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861411.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HFG9698622.1"
                     /translation="MNFKKLGILGLVSVFTLATITGCSSNNNKDKNNDKDTSSKKVTM
                     VLDWTPNTNHTGLFVALDKGYYKEEGLDVEIVQPPESGAETLVATGKADFGISYQEQV
                     TYAKTSEDPLPIKAVATVIQHNTSGFASPKEKNITTAKDFEGKTYGGWGSPSEEAVFK
                     AVMKKNGADFNKLKIVNTGQDDFFAAMKTVDFAWIFEGWDAVKADLIGYDLNFIPVKD
                     LDERLDYYTPLIISNETVLKDNPELAKKFLKATTKGYEYAIKNPEESAKILVKHAPEV
                     DEKLALKSQEYLASKYKDDAPRWGEMKDSVWNNYTSFLKEYKLIDKDMKASDAYTNEF
                     LPQ"
     gene            complement(14243..15013)
                     /locus_tag="ACGI5H_002926"
     CDS             complement(14243..15013)
                     /locus_tag="ACGI5H_002926"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435260.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HFG9698623.1"
                     /translation="MKNLEIIDKVKDSIYPIATFLFILILWQSMVGVLEVPQYILPTP
                     VDIINVFFKDYQNLSMHAVVTIGEAILGFIVAIIISLVIGILMDFVSIIKKCLYPIML
                     VTQMIPTIIIAPLFMIWFGFGTMPKVLMVMLTCFFPILISFVDGIENIDKDYLNLFKT
                     MDSNKVNTFIHLKFPMAMDKFFSGLKISATYAVMAATVAEWLGGTKGLGVYMLRSKSA
                     YALDKVFASTILVVIFSLMFVGIVQAVKKVVIRHRLID"
     gene            complement(14988..15278)
                     /locus_tag="ACGI5H_002927"
     CDS             complement(14988..15278)
                     /locus_tag="ACGI5H_002927"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424145.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MTH1187 family thiamine-binding protein"
                     /protein_id="HFG9698624.1"
                     /translation="MVIADIAVMPLRPYKGEEEMYKVVDACIAEIEKSGLKCEIGAMS
                     TTVEGDFDEVFELLKKVHKIPFNLGCERVITVARVDEKAGGLTIDEKLRNHR"
     regulatory      complement(15409..15508)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00059"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="TPP riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="thiamine pyrophosphate"
                     /db_xref="RFAM:RF00059"
     regulatory      16129..16218
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF01051"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="cyclic di-GMP riboswitch class I; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /bound_moiety="cyclic di-GMP"
                     /db_xref="RFAM:RF01051"
     gene            16271..16447
                     /locus_tag="ACGI5H_002928"
     CDS             16271..16447
                     /locus_tag="ACGI5H_002928"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9698625.1"
                     /translation="MFMDKMDRCTHILTAYICSSRDYCNFIDTQLNDFILEYGENVVE
                     SCLHQVMVLVSRYN"
     gene            complement(16562..16918)
                     /locus_tag="ACGI5H_002929"
     CDS             complement(16562..16918)
                     /locus_tag="ACGI5H_002929"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428797.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="winged helix-turn-helix transcriptional
                     regulator"
                     /protein_id="HFG9698626.1"
                     /translation="MDIDNNFEEFPNIEERQKDFNCSIGFTMTVIGSKWRAIILWHIL
                     KQEPIRYSQLKKEVVHISHKILSQELKYLERDGLIKRISYPTIPPKVEYLSTKRGKSL
                     ESILLELCNWGKQYMR"
     gene            17295..17675
                     /locus_tag="ACGI5H_002930"
     CDS             17295..17675
                     /locus_tag="ACGI5H_002930"
                     /inference="COORDINATES: protein motif:HMM:TIGR00654.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003824 - catalytic activity [Evidence
                     IEA];
                     GO_process: GO:0009058 - biosynthetic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PhzF family phenazine biosynthesis isomerase"
                     /protein_id="HFG9698627.1"
                     /translation="MTNADGLSESQMQKIARELNNSETAFIFNNLAKNHQENYDVHIR
                     FFTPTNEVPICGHATIAAHYVRAIENQFNNKTVFQKTGAGILPVDIIKKDNDYEIIMT
                     QGKIEVSPPLQQTYQKRLLNAFGI"
     gene            17735..18133
                     /locus_tag="ACGI5H_002931"
     CDS             17735..18133
                     /locus_tag="ACGI5H_002931"
                     /inference="COORDINATES: protein motif:HMM:TIGR00654.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003824 - catalytic activity [Evidence
                     IEA];
                     GO_process: GO:0009058 - biosynthetic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PhzF family phenazine biosynthesis isomerase"
                     /protein_id="HFG9698628.1"
                     /translation="MIGIKELSTLNSLSPNLYELSKISQEIKCNGYYIFTLHNKETLQ
                     VHGRMFAPAIGISEDPVTGNANGPLGAYLVHYKVIPTPNTEFIFEAVQGEAIKRKGKM
                     LVKVIILDNKPVEVKIIGKAVIAFSTNIEI"
     gene            18364..18975
                     /locus_tag="ACGI5H_002932"
     CDS             18364..18975
                     /locus_tag="ACGI5H_002932"
                     /EC_number="3.6.1.55"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893378.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005777 - peroxisome [Evidence IEA];
                     GO_component: GO:0005829 - cytosol [Evidence IEA];
                     GO_function: GO:0000287 - magnesium ion binding [Evidence
                     IEA];
                     GO_function: GO:0003986 - acetyl-CoA hydrolase activity
                     [Evidence IEA];
                     GO_function: GO:0008413 - 8-oxo-7,8-dihydroguanosine
                     triphosphate pyrophosphatase activity [Evidence IEA];
                     GO_function: GO:0010945 - coenzyme A diphosphatase
                     activity [Evidence IEA];
                     GO_function: GO:0030145 - manganese ion binding [Evidence
                     IEA];
                     GO_function: GO:0035539 - 8-oxo-7,8-dihydrodeoxyguanosine
                     triphosphate pyrophosphatase activity [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA];
                     GO_process: GO:0009132 - nucleoside diphosphate metabolic
                     process [Evidence IEA];
                     GO_process: GO:0015938 - coenzyme A catabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="CoA pyrophosphatase"
                     /protein_id="HFG9698629.1"
                     /translation="MINDIKNKFKNYKPYINGYKNMKRASVLIPIVEINNTHYILFEV
                     RSKNLKHQPSEISFPGGKIESGETPYEAVIRETCEELGTFSDNIEVISSLDLLITPVK
                     FIIHPYLGYIKNINNLNINKDEVDHTFLVPIKYLLENPPNTYSNTVKVFPDENLPYGS
                     IPNQKDYKFESGSYPILFYKYKDYVIWGMTAKILENFLNFLSE"
     gene            19273..19611
                     /locus_tag="ACGI5H_002933"
     CDS             19273..19611
                     /locus_tag="ACGI5H_002933"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889960.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3784 domain-containing protein"
                     /protein_id="HFG9698630.1"
                     /translation="MFAVGFVVIIALAFFILSVLLFNGKASMLLAGYNSMSKKEKARY
                     DKKKLCRSSSIVTFIVSIMLFIMAFLGYRIESGQMDEKKMVPFSIIFIIVILSSVFFN
                     ILYSNKKCKK"
BASE COUNT         6518 a         3249 c         2159 g         7964 t
ORIGIN      
        1 tttgatgata aaagctattt tccttctaaa taaaaaattt gtctaaagtt tctaaaaaat
       61 ttagacaaat cttaggttat tactctttaa attattttta aattattttt aaattattcc
      121 aaatacgcca aataatattg gtataaatat agctggtaac aaattggcta cttttatatt
      181 cgttaattta agtacattta gaccaagtcc tataattaat aaacttccag ctgctgtcat
      241 ttctgtgact acaggatcac ttaaaaatcc atttaaaaat gatgctccca cacatataat
      301 accttcatac aaaaatacag atattgcaga aaacattaca cctataccta aagaagcagt
      361 aaatataatt gaagctattc catctataac agattttaca aataaagtat catgacttcc
      421 tgtaagacca ctttctaatg aaccaactac tgccatggct cctatacaga ataataaact
      481 agatgatata aaaccctctg ctatagaatc ttttttattt cctttagaaa atttactttg
      541 taaaaaagca cccaacttat ttacccattt gtcaatatct attaattctc ctatcagagc
      601 acctacagct acggatatta ttgtcactaa tgtgtttttt ccttctagtg ctcctgatat
      661 accaatgtac aatacacata aggcaattcc attcattata gtatcgctta ctctttgagg
      721 taatcctcct tttattataa gacctactat acatccacct gcaattgcta gactatttgc
      781 tattactcca aacatttttt ctcccctcga ttagctaatt gaaatttatc ctattattaa
      841 aacctaaaca tctatacttt gtattggata ttttaaatat tccaaaaatt cttcaaaacc
      901 ttttctagat atatttacag ttttagtatt tatgttagga tgaaaattta agtaatcttc
      961 tttaattaca tctttatcta tgtaaagctc aacttttctt tctgtatcat ttattaatga
     1021 aaaaggattt acacttccag gaagaagttt aagtacattg tatagtcttt caggtgaagc
     1081 aaacgataat ctagaacttc ctatcttatc tttaagtgag tttaaatcaa cttgtttttc
     1141 tcctttaact acaataagat aatacttatt tcctttggca tttcttaaaa ataaattttt
     1201 acattgacac ccctttgtta ttccatctaa aatgactaat tgctctgctg tatatacagc
     1261 ttcatgctct actacatcat attcaacatt taatttatcc aaaatatcat atattttagt
     1321 ttcattcatg ctagattcat tttcatcttg ttctttttta ttatttaaat cactcatact
     1381 tttctcctta aacacttcat cataatatca ttgtgaggta ttattctact atagctattg
     1441 ctcttactgg agctccatca gcatcattat acttaaatgg tgctgctata aatagaaatt
     1501 tttctggaac attttctaaa tttgtaagat tttctatgat tatttttcct ttttcaaata
     1561 aaatatgatg cacttcaaat actgatgtgt catatctatc cactgatagc atatctattc
     1621 ctatgccttt tatattagta ttagctatat agtttgcagc ttcttttgtt aatgtaggat
     1681 aacctacata gtactgcttt ttatcccaaa attttgacca acctgattta aatattataa
     1741 aatcactatt ttttatttca tcttcatatt tttttagata ttctaattct atattctcat
     1801 ttcccttttc aagttccaat acataagctt tcccaacaaa attttctata tccaacttat
     1861 ctagggtctc acctttagta tacatatgtc ttggtgaatc catatgagtt ccattgtgag
     1921 aaaatacact aattaatgtt tcttgataac cattttcttc aataatagct actttcttga
     1981 tatctggtct attaggctct gcatatacag gcatgtcatt atgtgtcaca tgagttaaat
     2041 caaaaacctt catctttata taccccctat gtttttattt tctattatat acctaaattc
     2101 attttatttc tatcagattt tattccatta tataccatac tactatatat tttttataaa
     2161 cctcaaggga tttaccgaaa aatcttggaa agaattatca gtaaatataa catcttcacc
     2221 caaaaaacgt ttataccttc cttcttcttt ctttaaagta attctctgtt tttgtgaatg
     2281 attattaaaa accattatct taagaggagg tttttttcta ttagtctgca ctctttttaa
     2341 catgtatttt atgtgcatat cagcttcagg aaatgaatat ccacaaaata ttaaaaggtc
     2401 agtatctctt aaagtttttt ctgtttcatt ccaaacatca cttaaaaata tgtttgacat
     2461 attcttaaaa tatgttggtg gcactataat aggttctgtt aactcaccac actctaaaca
     2521 ttttgtctct gaactatttt caataagctt catgacacca ccttcatgtg gtgtaagagt
     2581 tacactatta caaatggggc aataaagcca attcaatgac ccatgtatct tatataattt
     2641 gattaatggt tcttttggtt ttctccaatt taactcctct ttaaaatttg taaactccac
     2701 accataatca agcataattg gcaaatcatt cttatctctt aatccagtaa ctgtattgtc
     2761 tatatgtata tcataatttg cactaataaa agtagtatca agaagcaaat cattttccaa
     2821 aagattttca actaaaagtt tatgatattt attatctgtt ctaggtgtat tatgaattgc
     2881 ttcagccatt agcagtatta aatattgtct taaaaaacgt atactatcac ttctgttatt
     2941 tagattttct agtccaaaat ttctaaatgc ttcttttctt tgttctgcta agtctaaaag
     3001 acctaaaact tcttcaaagg taggaaaatt tgcattatct atattatctt ttactatatc
     3061 aatattgaac atctgtttaa agaaaatata caattctcta ttcattttgg tattataatt
     3121 tgtgggattt agttttttaa aatattcgct aaaaagttca ttttgaatag gtagattctc
     3181 tgctgctgaa gctcctgctc ctaaaaatat tgctattttc atatagttcc tcctaatata
     3241 aatattactc ctatttttat atccattaaa tatccatatc atttatttta tgatacaaca
     3301 ataaagctgt cttttactag aaaaaatcct attacaagac agccttatat tatattaaat
     3361 ctttaataat tcgtaaatag aaagagcata tatttgagta gcttttataa tatcctctac
     3421 tattaagtat tcattagctt ggtgttctgt ttctggtttt cctggaaaaa tagctccaaa
     3481 tgcaacacaa ttatctaaag ctcttgcgta tgttgctcct ccagatgaaa gtggtgttcc
     3541 atcaagacca gtttcttctt catatacttt tctaagtgtc ttaacaagaa gagtatcttc
     3601 tggaacatag attgaatcca agaaatcata ttcttcataa tttaaattgt atttatctgt
     3661 cattttcttt aactctttta caaaatcatc ctttttgtat gttactggaa tccttacatc
     3721 tattcctgca aattcttttt cgttatcaat agttactcta cctatattta ctgttagttt
     3781 acctgataca tcatccttgc agttaggaat tatattgttt ccattagcat cttcaccaat
     3841 aacttctgct aaaaacttaa ttatattaga atctatacct atattattaa gagctataca
     3901 aagtctagcc actgcattta taccagtatc acttgctgct gaatggacac tctttccaat
     3961 tatacagatt ttattacctt caacagtata ctcaaaattt aatttattaa gttctttttt
     4021 taatttatca gagtattttc caatatagat tgctttacct ggaactgcat ttaaagcctt
     4081 tccaactgac aactctatat cacttttgct atcacaagtc aaatgaactt gtaaaagacc
     4141 tttctctgca tttgttattg ggaatctaga atctggagta aatccatagt ttggtatttc
     4201 ttcattattt tctttatatt tatttataca tctccaaaga ttttcttcat cagccccaaa
     4261 aatgaatctt atcctcttat taaagtctac atttaaatcc ataagagctt tcactgcata
     4321 aattgctgat attgtaggtc ctttatcatc ttgtgttcct cttccataca atttaccatc
     4381 ttctaaaaca gcttcaaatg gagggtaatt ccagctttct aaatcacctt ctggaaccac
     4441 atcaacgtga ccaagtatac ctatcatttt ttcaccttgt cctatttctg catatccata
     4501 atatccatct ttgtatactg tcttaaatcc taaagattta cataaatcta atatacctct
     4561 taaagcttta tctacatttt caccaaatgg gcaattttca gttgcttcag atataacact
     4621 aggtattttt acactttctt gtattgaaga aatcatttca tcttgtagag aatttacttt
     4681 ttctttaatt tgctctttca tattatcacc cttcaatttt catcataata tactaataaa
     4741 tattttgacc ttttaaaaaa aaaatatgct tattttttca gtttttttat aaattcaatc
     4801 gcttttaaag tccccatttt tgaatggtca aatgtaagtc caccttggaa ataaacatta
     4861 taaggaggtc ttattggagc atctgcactt aattctatag aagaaccttg tataaatgct
     4921 cctgctgcca ttatgacttc actttcgtat ccaggcatgt cccaaggaac aggttttaca
     4981 taagaatcga ctggtgcagc ttcttgtata ccttcacaaa aacttattac ttcatcagca
     5041 ttattaagtc taatacattg aataatatca cttcttaagt catcatattt tggtaataca
     5101 tcatatccta atttttcaaa agctcttgag caaaagatag ctcccattac agcctgagat
     5161 actatataag gcgccaagaa aaaaccctga agtacatttc tagttgttcc aaaagtaaga
     5221 ccacattctt ttcctattcc aggagaagtc attctataag atataagctc aatcaaatct
     5281 tttctaccag ctatatatcc acctgtcaat gcaagcccac caccaggatt ttttattaaa
     5341 gagccagcca taacatctgc tccaacatca gtaggctctt tggtatctaa aaactcacca
     5401 taacaattat caaccattac tatagcttct ggtttaacag actttattac ttctatagct
     5461 tcttttatat cactaattga aagtgatttt ctccaagaat atccttttga cctttgtatc
     5521 ataacgagtt tagttctatc atttattttg tttttaattc cttctaaatc taagtttcca
     5581 tcctctaaaa aatctacatc atcatatgta acaccatact ctttcaatga acctttttct
     5641 tctcttatgc ctataactcc ctctaaagta tcatatggtc taccagtaac agataaaatt
     5701 tcatctcctg gtctaactat accttgtata cataaagtaa gtgcatgtgt accatttaca
     5761 attattggtc ttacaagagc atcttctgta ttaaatactt tagaataaat ttcctctatt
     5821 ttttcacgac caatatcatt atatccatat cctgtagtcc agttaaagtg catatcactt
     5881 agtttagatt cttgcatagc ttttaaaact ttatattgat tatattctct tatttctttt
     5941 atttcttcaa acttatcttt tatttcttcc attatttctt gcgatagttt aaaagtatca
     6001 tcatctattc catagtagtc ttttaataat tcttttgtct cattaagcat tttatcacct
     6061 gtctctttat tattttattt aaacatgtaa aggagactat tttactaaaa caaataaatt
     6121 atagtttata agttagtata agtctcctct caatcatctt aaattaaatt aattatctat
     6181 ctgttgttat tattattgtt gttttggttt tgatttgtta gattaatata ctttccaggt
     6241 tgtatagttg atacagcatg tttataaatc atgttttgtt gtctattatc cccttctatt
     6301 aatattatat aactatcaaa cccctttaca agccctttaa cttgcactcc attaactaaa
     6361 tatatagtaa caggtatcct ttctttcctt gcattattta aaaacaaatc ttgtaaattt
     6421 aaaactgtat ttttcattag atttgtaccc tcccaagatt aaattgaact tctaaaatat
     6481 tcctacctta tattctatat aagttatgac aaattttcaa tattaagttg tatacttaaa
     6541 aatttatata ttattttata gaatctttaa tatataagat tatttcattt tttaattcgt
     6601 ctatattttc atattggtct aaatcaaacc attttgctgt tttatatctt ttaaaccatg
     6661 ttatctgacg ttttgcatac cttctagaat ctcttttaat tatttcaata gcttcttcgt
     6721 atgtatattc tccatccaga tactttaata tctctttata acctatacct tgcattgata
     6781 tcatatcttt tttaaatccc atacttaaaa gtttttttac ctcttcaacc aatccatttt
     6841 taagcataat atcaactctc atatttattc tttgatacaa atgttctcta tctctattta
     6901 gaactattat tattggttga tattcttcat taaattttaa atcacttgaa aaatcattca
     6961 ttttcttacc acttagacaa acttcaagag ctcttatgac ccttttagta ttgtttttat
     7021 ggattctatt agcagattct tcatcaagtt cttttaactt attatgcatg taatctattc
     7081 ccttttcagc aagttgtttt tgaagttctt ctcttaattc attattggca tcagattgtg
     7141 caaaatccat attatatatt aaagagttta aataaagtcc tgtgcctcca gttactaaaa
     7201 cacatttttc ctttttattt atttcatgta tatatttttt tgctctttgt tgaaactctg
     7261 aaactgaaaa tggatagtca ggcttaactt catctataag gtaatgcttc actccttgca
     7321 tctcttcctc tgtaactttt gcacttccaa tatccatata ttcatatatt tgcatagaat
     7381 cagctgaaat tatctctgca ttcatatctt ttgctaattt tattgacaaa tctgtttttc
     7441 caacagcagt tggacctgta agtattataa gtggtatttt tttcataaca ttcctttcca
     7501 tatattttaa atatccaaat attttacata attcttttaa acattttttc tatttctgtc
     7561 ttagatattt cgaccattat aggtcttcca tgaggacatg taaatggatt ctcacacttt
     7621 tctagctgtt ccaataaact ttttatttca atatcgtata ttttatcatt tgcttttata
     7681 gcagacctac atgccataga tgcaaatctc tctcctttta aatcataatt acttgtaatt
     7741 tcttctatat tatcaattat ttgaagtata aatttctcgg tttcaggtac tccaaatata
     7801 gtaggaacac atcttaccat tatatgatta ttgccaaaaa tttctagctc aaaaccaaat
     7861 ttcataaata actccaagtt attttcaatt tgaagcatat ctacatttga tacttcaata
     7921 accactgggt ctaaaagtat ttgcatattt atatcttgtc tatagaactt ctccatatat
     7981 ctttcatata gtattctttc atgtgcagca tgttggtcca acaaatacat agaatcgtct
     8041 ttgctcaaaa ttatataagt attaaataca actccaatta cagaatatcc gtataaagaa
     8101 aacttgcgtt ttgaactaca caagtattct tcttcactgt ccttaatact atctcctaag
     8161 taataatttc cttcattttt aattccatca acttgaaact cttcttgtat attatcattt
     8221 gcactatctt cacttagata attaatgttt tttacatcat cttctacact tgcatttagg
     8281 acttcactta ctgattgaaa ttcatttatt ggtttttcac ttgataaagt aacaacttca
     8341 atgacttcat ccttaccttt agtaatatta ctatttttag gagtagattc taataaatca
     8401 ttatttctta atttataatc tgtacttttt tctctactgt taatagcgat tctaggttgt
     8461 gtttttttat cactataagt agcatatttt ccaataagat ttgagtgtat taatttaacc
     8521 tttaaaaaat ctctaagttc tatatacact tcttgttctt tttcaaattt aatttcaagt
     8581 ttattggggt gtatatttac atctatacat gatgggtcta cttctatatt taagaagcac
     8641 actgcatgtt tacctattgg aattatagac ttataacttt ctgttattgc atctatgatt
     8701 attttacttt ttacaaatct tttatttata tagatatgtt gtaagttttt atttgaacgg
     8761 tatatattgt tattacctat atatccattc attttaaagt gattgcactt aaactctaca
     8821 tctattatat tttccgttat ttcttttcca tatatacttc taatagtgtt tacaagcttt
     8881 ccatcccctg gagtatttag catctgttta ttgttatttg tatatttaaa ttgaatgttt
     8941 ggattaccta ttgcaagttt atttatcaaa tcacttatat ttatagtttc tgcatgagta
     9001 gattttaaaa atttctgtct tgctggtgta ttaaagaaaa tatcttttat aatgatggta
     9061 gttccattag tagaacctat tggttctttc gatattattt ttccaccttc aacatatatt
     9121 ttagttccta ttatttcatc tttagtttta gttgtcattt ctaattttga tacagctgaa
     9181 atagatgcca atgcttctcc tctaaaacca agagagtata aatcatacaa atcatcaatt
     9241 tttttaattt tactagtagc atgtctcaaa aatgattttt caacttcact tgaaggtatt
     9301 cctattccat tatctgtaat cttaattaga ctttttcctc catcaattat atctatggaa
     9361 attttatttg cacctgcatc aatggagttt tcaataagtt cttttactac agaagaaggt
     9421 ctttctacaa cttcacctgc tgctatctta tttatagtca aatcatctag gatgttaatt
     9481 atatttttca tttttacacc tctaagattt tatttctttt gcttttcttt gaagattata
     9541 aagagagttt atagcatcta atggagtcat atttaaaata tccagattta aaatttcttc
     9601 tgatagtata tctctattta cactatcaaa agagatttga gttaaggcta cttcttttac
     9661 agaatccact tgattaattt tctctttatc atcattttgc tttattaaag caacttcatc
     9721 atttaatgct ttaaatttag aatttaattt atcataatcc ttttttatat gtttgtagtc
     9781 ttttactata agttcatgtt ctatttttag agattcatat ttattcttaa aattactttg
     9841 atttacctta actaattctt cgtccaaatt actattaatt atattattgt tttctttatc
     9901 tccatttatt gcaacactgt tgtaaacatg atttttttcc aagtctttaa gtatatattt
     9961 tgctctttct atgacttcgt ctggtaattt agctaattta gcaacatata ttccataact
    10021 cttgtctgct ccctgaggaa ttatttttct taaaaatatt attccttccc catcttcttt
    10081 gactgctatt gaataatttt taacctcttt aaactcttct tctaaatcag taagttcatg
    10141 ataatgtgtt gcaaataatg tcttacatct aatatttttt tgaatatatt ccactattga
    10201 ccatgctaaa cttataccat cataggtact agttccacga cctatttcat ctaatataac
    10261 taaacttctc tctgttgcat tttttaatat aagggatact tcgttcatct ctaccataaa
    10321 agtagattga ccttgagata aatcgtcact agctccaact cttgtaaata ttctatctaa
    10381 tattggaata tcagcagact ctgctggtac aaatgagcct atatgtgcca taagagctat
    10441 tatagcagtt tgtctcatat atgttgattt acctgacata ttaggaccag ttattatgtt
    10501 aataatgttt tctccacgat ttaaataagt atcatttgga acgaaatttt cctctcctac
    10561 tatattttcg acaacaggat gtctaccatt tcttatatca agtttattat tttcatttat
    10621 tgctggtttt acatagttat ttatatgtgc aactgttgca agggacacaa aaacatctat
    10681 attagctata gtcttagcca ctttttgtat tctatctatg tttttatata ttgtatctct
    10741 tatctctaca aatatctcgt attctaaaga tttaatcttt tcctctgcat gtagtatctt
    10801 ttcttctatt tcctttaatt ctggagttat atatctttct gcattactaa gtgtttgctt
    10861 tcttatatat gtctcatcta gctttgcctg tttaaagtta gcttttgtta tttctatata
    10921 atatccaaaa actttattaa agcctatttt taatgattta actcctgttt tttctctttc
    10981 cctgttttct atttccttta caagaaaggc tccattctta gaaatctctc ttagttcctt
    11041 aagttcatca ctaaaatctg atttaattat gtttccatct tttatggtta tcgtaggttc
    11101 ttctagaata gcttcatcta ttaaattgta tatatcatct aatttatcca tttctgaaac
    11161 atactctttt aggatttttg catttgataa atttatagta tcttttaaat taggtaactt
    11221 ttctatcgaa ttttttaagt gaattaactc ttttggtgtt actctctcaa atgctatctt
    11281 tccacatatt ctttctatat cgtatatatt tttaagtata tcatttaggt cttctcttaa
    11341 tataaagtca tcttttattt cttctattac atctaatcta ttttcaattt tagatttatt
    11401 tatcaaaggt tcttctacat attttcttaa aagtctacct cccattgctg tagaagtttt
    11461 atcaagtacg tgtaataatg aacctttttt cttattccct cttatagttt gagtaagttc
    11521 taaattagtt ctagtaaaca tatctagaac catatattct gatgaattgt atatatttat
    11581 attattaatg ttagatgtta tttgtttttg agtattgtat atataattca gaagaattga
    11641 taagcttgac tttattagac ctttatcatc aaactttagt ttttgtagat aaacatctgg
    11701 aaaatattct tttaatatat ttatatccaa atagttatca ctaaaacttt catttatgta
    11761 tatattactt acagtagcta tatctctaag attttctata aagtctaaat catttataat
    11821 tatttcagtt ggatggattt ttgcaatttc ttcaattacc ttatcttcat ttaaacatgt
    11881 tgcattagtt tctcctgtac ttatatcaac ataagttaga cctatattag taccatcctt
    11941 atacaaagat aataaataat tattcttttt attttcaagt aaatttccat ctaaaactgt
    12001 accaggagtg atgactctta taacctctct tctaacaatt ccttttgctg tagatgggtc
    12061 ttccatttgt tcacctattg ctactttata tccattttca actaattttg atatatatga
    12121 attggctgag tggaaaggaa caccacacat aggagcacgt tcttctaaac cacaagcttt
    12181 tcctgtcaat gctatttcaa gagcttttga agctactaat gcatcttcaa aaaacatttc
    12241 ataaaaatct ccaagtctaa aaaacagtat acagtcttta tatctatttt ttacttcaag
    12301 atactgtttc atcataggag ttaatttatt catatctatt tgcattatca aacctccttc
    12361 ttttctaatt aaatattata tcatagtaga tgattattat taacacaata tataaaattt
    12421 tgacatataa ctaaaaacaa tccaaaatgt atactcacat tttggattgc taagtttaat
    12481 gcttattaaa taaaaatatt ttttttacaa taaagatatt atttcttttt taagtttaat
    12541 gatattttca aggttatctt catttaactt tctactatct ataacaaatt ctttctttac
    12601 tattgatggt ttttttgaaa taacataaat tctgtttgat agcattatag cttcgtcaat
    12661 atcatgagtt ataagaagta ttgttgaatt tacttttttc ttaacatcta aaagccattt
    12721 ttgcatggat gttttagtta atgaatcaag tgccccaaaa ggctcatcta aaagcattat
    12781 gtcattagaa tttataaaag ttctcaagaa gttagctctc tgtctcattc ctccagaaag
    12841 ttctgaagga tatttatctt catatccgct taatccaaac acctcaaaat aaggttttac
    12901 cattgaccta gctttactct ttttttcttt ttttaaaatt agtggtagtg acacattatc
    12961 tattatagtt ttatatggca agagtaaatc tttttgatac atataactat acttaccatt
    13021 tatattcact ttgccactat cataatctgt aagtttagtt ataatattaa aaatagtact
    13081 ttttccacat ccacttggcc ctaatataga aacaaactca ccttcataaa catcaatact
    13141 tatatctttt aaaacttcaa tatctttata agtttttgat acattttcta tagatacttt
    13201 tactttttta ttgtggtaaa aattcatttg tgtaagcatc acttgccttc atatccttat
    13261 ctattaattt atattctttt aagaatgatg tatagttgtt ccatacacta tctttcattt
    13321 ctccccatcg tggtgcatca tctttgtact tgcttgctaa atattcttga ctctttaaag
    13381 ctagtttttc atctacttca ggtgcatgtt ttactaaaat ttttgctgat tcttctggat
    13441 tttttattgc atattcataa ccttttgttg tagcttttaa gaatttttta gcaagctctg
    13501 gattatcttt aagcacagtt tcattagaaa ttataagtgg tgtataataa tccaatctct
    13561 catctaaatc ttttactggt ataaagttta agtcatatcc aattaaatca gctttaactg
    13621 catcccaacc ttcaaatatc catgcaaaat ctacagtttt catagctgca aagaaatcat
    13681 cttgaccagt attaactatc tttaacttat taaaatcagc tccatttttc ttcataactg
    13741 ctttaaaaac agcttcttct gatggagagc cccaaccacc ataagttttt ccttcaaaat
    13801 ctttagctgt tgttatattc ttttcttttg gtgatgcaaa cccagaagta ttatgttgta
    13861 taacagttgc tacagctttt attggaagtg gatcttcact agtctttgca taagtaactt
    13921 gttcttgata gcttatacca aagtcagctt ttcctgttgc tactaaagtt tctgctccac
    13981 tttcaggtgg ttgtactatt tcaacatcca aaccttcttc tttatagtaa cccttatcaa
    14041 gtgctacaaa taatccagta tgatttgtat ttggtgtcca atcaagcacc atagttactt
    14101 ttttagaaga agtatcttta tcattgtttt tgtctttatt gttatttgaa gaacatccag
    14161 ttattgttgc caatgtaaaa acacttacta aacctaatat tcctaacttt ttaaaattca
    14221 taattgcctc cctcaaatac ctttaatcta ttaatctatg tcttataaca acttttttta
    14281 cagcctgtac aattcctaca aacattaaac taaatataac tactaatata gtagatgcaa
    14341 atactttatc aagtgcatat gcactttttg acctaagcat ataaacacca agtcctttcg
    14401 ttccacctag ccattctgca acagttgctg ccattacagc atatgttgca gatattttaa
    14461 gtccagaaaa aaatttatcc attgccatag gaaatttaag gtgaatgaat gtattaactt
    14521 tatttgagtc catagtctta aataaattta aataatcttt atcaatattc tcaatgccat
    14581 ctacaaaact tattaatata ggaaaaaaac aagtaagcat taccatcaat acttttggca
    14641 ttgttccaaa tccaaaccat atcataaaga gtggtgctat aattattgta ggtatcatct
    14701 gtgtaaccaa cataatagga taaagacatt tttttattat tgatacaaaa tccatcaata
    14761 ttccaattac caatgatatt ataattgcga ctataaaacc aagtattgct tctcctatag
    14821 taaccacagc atgcatggat aaattttgat aatctttaaa aaacacatta attatatcta
    14881 ctggtgtggg tagtatatac tgaggaactt ctaaaactcc taccatagat tgccaaagaa
    14941 taagtataaa caaaaatgtt gctattggat atatactatc tttgacttta tctatgattt
    15001 ctaagttttt catctatagt cagacctcca gctttttcat ctactctagc tactgttatg
    15061 actctttcac atccaagatt aaaagggatt ttatgtacct tttttaataa ttcaaaaact
    15121 tcatcaaaat caccttcaac agtagtgctc attgctccta tttcacattt aagaccactt
    15181 ttttcaattt cagcaataca agcatctact actttataca tctcttcttc acctttgtaa
    15241 ggtcttagtg gcattactgc tatgtctgcg attaccattt aaatcactcc tttaaaaata
    15301 attaatacct actaggtata ttttgttttt tattaaaaaa ttttattact aaaaagatat
    15361 tatatttaaa taaaagaaaa gtcttatcca aaataggata agacttattt ttatcttaac
    15421 tggtctccct acactggcat tatccaaaca ggttcaaagg gtcgagataa aatctcctct
    15481 cagcacatta gctccccgaa atatattata tcttttctac ttgattatac tacacttatc
    15541 atattttaac aaatttttta tttatattag atattttatc cgttcaaaaa tatctaatat
    15601 aaattgtaca ttattacacc aaataaatta tcttaaaatg gtattttatc aacatcttcc
    15661 aaaactagat taactgaatt ttctagtttt tattttgcta tttcaagcat atttggatgt
    15721 atatcaattc catacaaata ttgtgctaaa tttctgtttt cactcatcta atttgcaatc
    15781 gttacagatt acagattaga aacagttttt agactctact tatctttatc tacaaaaaat
    15841 ctttcaataa attcattaat aatattcagt aatctaaaaa taaacctcta tctggatttt
    15901 taagatacaa accttttagg aagtatcttt tgtgataata taaaaattac tcgtcattat
    15961 catcaaaatc ctcagcaacc aacattttat ataagaatca aactctataa tataattatt
    16021 ttatccaatt tatttttgag aaataaaata tttttttaat ttttaaattt tttaatatgc
    16081 accttgaaaa aaagaaacgt tttcctatat tatggtaata gtagaataaa actaaatagg
    16141 caaaactaga gaaatttagt gacgcaaagc tatagggact aagacttatg aaatgagtta
    16201 tgtcagccag ttgccaaaga gatattttct ttttgttttt atgaatgttt tttaggggga
    16261 tatatgatat atgtttatgg ataaaatgga tagatgtaca catatactaa ctgcatatat
    16321 atgcagttca cgcgattact gcaattttat agatacacaa ttaaatgatt ttatactaga
    16381 atatggagag aatgtggtag aatcttgttt gcatcaagtg atggtattgg taagcagata
    16441 taattaaaga aattttattt tctagaaaac cctttttagt tttatctacg ttttataatt
    16501 cattaaagaa ctaattaaaa taagcttcat tatatatttt tcatgaagta aacagttaag
    16561 tttatctcat atactgttta ccccaattac ataattctaa taatatagat tccaatgatt
    16621 taccacgttt agtagacaaa tattcaactt ttggaggaat agtcggataa gaaatcctct
    16681 taataagtcc atctctttca agatacttta attcttgtga cagtatctta tgacttatat
    16741 gaacaacttc tttttttaat tgactgtaac gtattggctc ttgttttaaa atatgccata
    16801 aaataattgc cctccattta cttcctatca cagtcatggt aaaaccaatt gaacaattaa
    16861 aatctttttg tctttcttca atatttggaa attcttcaaa attattatct atatccatct
    16921 caatcctctc tttcaaaata gtaagtatct aactaaaaag tgcattcttg tttagcgtac
    16981 taattcgtaa tataatcttg attaaaaaat agctatgcac actcgtgact ttagtcatgg
    17041 gaggttcagt gtagcataga gccttacata atactacttt tttagatgta tatgtttaaa
    17101 ttttaatata gacatatgtt attttattaa ttttatttaa acagataata ataaataata
    17161 atttatctca agttttctat gtagataaac taatctaatg tttagaaagg attatataat
    17221 atgaataaaa aatttcgtct ttatcaagtt gactcattac aaaagaaaaa tttacaggta
    17281 atccagctgg tgtaattaca aatgctgatg gcttatctga atcacaaatg caaaaaatag
    17341 caagagaatt aaataattca gaaactgctt ttattttcaa taacttggct aaaaatcatc
    17401 aagaaaatta tgatgtacat atcagatttt ttacaccaac taatgaggtt cctatatgtg
    17461 gtcatgctac tattgctgcc cattatgtta gagcaataga aaaccaattc aataacaaaa
    17521 cagtatttca aaaaactggt gctggaatat taccagttga tattataaaa aaagataatg
    17581 attatgaaat aattatgaca caaggaaaaa ttgaagtatc tccaccatta caacaaacct
    17641 atcaaaaaag attacttaat gcatttggta tttaaaggaa gatattcgta cagattgtcc
    17701 tattgccata tcatctacag gacattcaaa agttatgatt ggaataaagg aattatcaac
    17761 attaaatagt ttatctccaa atttatatga attatcgaaa ataagtcaag aaataaaatg
    17821 taatggatat tatattttta cattacataa taaagaaact ctacaagttc atggaagaat
    17881 gtttgctcct gcaattggta tttcagaaga ccctgttaca ggaaatgcta atggaccctt
    17941 aggtgcgtac cttgtacatt ataaagtaat acctacaccc aacacagagt ttatatttga
    18001 agcagttcaa ggagaagcaa taaaacgcaa aggcaagatg ttagtaaaag taattatttt
    18061 agataataag ccagttgaag taaaaataat tggaaaagct gtaattgcat tctcaacaaa
    18121 catagaaatc taattataga ttccttctaa gtaaattttt gaacttttta atactaattt
    18181 aataacaaac taatttatat acaatcaaat taattttttt attatttgtt aatatatatt
    18241 tatcattata ttatataata atatagatag ttactatatc ttataattag ataaatcata
    18301 attatatatt attgttaaaa ctcaattata taatttttaa taatattatt ttaggaggta
    18361 aaaatgataa acgatattaa aaataaattc aaaaattaca aaccatatat aaatggatac
    18421 aagaatatga agagagcatc tgttttaatt ccaatagtag aaataaataa cacacactat
    18481 atattatttg aagttcgctc aaaaaatttg aagcatcaac ctagcgaaat ttcttttcca
    18541 ggtggtaaaa tagaatcagg tgagactcca tatgaagctg ttattagaga aacttgtgag
    18601 gaacttggaa cttttagtga caatatagaa gtaatatcaa gtcttgacct ccttataaca
    18661 ccagtaaagt ttatcataca tccatactta ggatatataa aaaatattaa taatttaaat
    18721 ataaacaagg atgaagttga ccatactttt ttggttccta taaaatatct tttagagaat
    18781 cctccaaata cttatagtaa tactgtaaaa gtttttccag atgaaaatct accatatggt
    18841 tcaattccaa accaaaaaga ttataaattt gaaagtggaa gttatcctat tctgttttat
    18901 aaatataaag attatgtaat ttggggaatg acagcaaaaa tactagaaaa ctttttaaat
    18961 tttttatcag aataacactc ataataaatt atcaaaattt ttacataaga aatttataaa
    19021 agtttctaaa tttaacaatt ctaaaatatc aataactata ttttgtagca cttttttatt
    19081 ttattattgt ttgaatattt gatggttttc aatgcaattt caacataaat actatatatt
    19141 agtgtatact gttgatgaat taaagtatga taatctattt aataaagtat gaagtaaatg
    19201 attttaatgt gcctttatgg taaaattact aataagtaat aaaattaatt aaaatatatg
    19261 gaggtcctta taatgtttgc tgtaggattt gttgttataa ttgcacttgc ctttttcatt
    19321 ttaagtgtac tattatttaa tggaaaagcc agtatgctac tagcaggtta taactctatg
    19381 agtaagaaag aaaaagcacg atacgataaa aaaaaattat gtagaagttc tagcattgtt
    19441 acttttattg tctctataat gctatttatt atggcgtttt tgggatatag aatagagagt
    19501 ggtcaaatgg acgaaaaaaa aatggttccc ttttctataa tatttataat agtcatactt
    19561 tccagtgtat tttttaatat cctctactct aacaaaaaat gtaaaaaata aatagttgta
    19621 agttgagcag ttaattataa aagattgact gctttttcat gtatattgac tactcttatt
    19681 aaatatttta acatttaaaa atctatgtaa aaataatgaa tatagtacaa acttctaata
    19741 atgattttac ctttgtggtt acagtccact atatataatt taatatgata acagggaatt
    19801 attaatgaca actaagtaaa cttttataaa atataataaa acaaaaatag atgtacaatg
    19861 aaattatatc ttatatcaaa tttattttta
//
LOCUS       DAYAOO010000076        19320 bp    DNA     linear   BCT 12-OCT-2024
DEFINITION  TPA_asm: Clostridioides difficile isolate ST8-SSI-h139-18
            SAMN40601845-rid21577343.denovo.076, whole genome shotgun sequence.
ACCESSION   DAYAOO010000076 DAYAOO010000000
VERSION     DAYAOO010000076.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN40601845
            Sequence Read Archive: SRR28438827
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 19320)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 19320)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-MAY-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-MAY-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002157583.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002157583.1
            Genome Coverage       :: 163x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/11/2024 16:19:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 4,038
            CDSs (total)                      :: 3,963
            Genes (coding)                    :: 3,930
            CDSs (with protein)               :: 3,930
            Genes (RNA)                       :: 75
            rRNAs                             :: 6, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 60
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 33
            CDSs (without protein)            :: 33
            Pseudo Genes (ambiguous residues) :: 0 of 33
            Pseudo Genes (frameshifted)       :: 7 of 33
            Pseudo Genes (incomplete)         :: 25 of 33
            Pseudo Genes (internal stop)      :: 11 of 33
            Pseudo Genes (multiple problems)  :: 8 of 33
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..19320
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN40601845-rid21577343.denovo.076"
                     /isolate="ST8-SSI-h139-18"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Denmark"
                     /collection_date="2018"
                     /collected_by="Statens Serum Institute"
     gene            217..2076
                     /locus_tag="ACGI5H_002934"
     CDS             217..2076
                     /locus_tag="ACGI5H_002934"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420306.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative bifunctional diguanylate
                     cyclase/phosphodiesterase"
                     /protein_id="HFG9698631.1"
                     /translation="MKRFLRRIILVLFILLIFISFISIKLIHNVGDYGKLINYVGIVR
                     GASQRLTKLEMNHQPNDELIEYIDEILQELITGHGDYGLVITDCNEYNEDLLLLEKKW
                     EDLNIEIKKVRMKEQNNQLLSISEEFFSLANDTVFKIENFSKEKSNYLMTLIIIISII
                     GILACIILILQYSKKMVRLEKLNVDLKNIAYKDELTGVNTIEKFKLDANQNICIHKDK
                     KFAVFYIDFENFKYINDIFGYDYGDMILKRYANLMMNDIGKYEIFAREIADRFVALRC
                     YVDKEDLVVRQRDVDNELINITNEIKNKHSITVVSGICCIEDVNEKLSIDGLINRANF
                     AQKTVKNKPGTNYAFYNDSIRKKMIEENTIKSRIHEAIEKREFIVYLQPKVNLHSQKI
                     NCAEALVRWLTPDKGIISPAIFIPVLEKNFFIALVDKYVFEEVCKWIRKRLDENKPFV
                     QISVNVSRIQFYNTKFVETYSNIQNKYRIPKNTIEIEFTESVAFENQKHLLEIIHDLH
                     ENGFTCSLDDFGKGYSSLSVLKDLPFDVLKLDSMFFKASLDKDKEKIVIKNIVHMLKE
                     LNITTVAEGIECKEQVEFLRDIGCDLVQGFVFYKPMPILEFEKILDKEFVYNS"
     gene            complement(2368..2967)
                     /locus_tag="ACGI5H_002935"
     CDS             complement(2368..2967)
                     /locus_tag="ACGI5H_002935"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454512.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TerD family protein"
                     /protein_id="HFG9698632.1"
                     /translation="MAIELKKGQKINLTKKENSDLGEILVNLNWNQKVQKKGFFGSLR
                     SSNIDLDLGCLFEMKNGVKGAVQALGNAFGSLDNPPFAQLDGDDRTGSNTQGENLRIN
                     GNKIKDIKRILIYAFIYEGVANWSEADGIVTIKQKQDSDLVVKLDEHKNGYNMCSIAL
                     IENVNDETFSVEKVVKYFKGHREMDTEFHWGLKWVAGRK"
     gene            complement(3070..3867)
                     /locus_tag="ACGI5H_002936"
     CDS             complement(3070..3867)
                     /locus_tag="ACGI5H_002936"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902687.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MetQ/NlpA family ABC transporter
                     substrate-binding protein"
                     /protein_id="HFG9698633.1"
                     /translation="MKFKKLLCLLLCLVLTLAVVGCSKAKDDKKIVVGATLVPGGELL
                     EELKPLIKEKGYTLEVKNFDDYILPNEALNNGEIDANLFQHEPYLKEAVKAKGYKIMA
                     GKKLYVCPAILYSYKIKSVDEFKKGDTIAISNNPSSCSKNLRYLESIGLLTLPKGDGL
                     VSPKDIIENPKGIQFKELDIAQIPSSLPDVTAAFIDTTYAVPAGLDAKKNGIYTAPIN
                     DEYANLLAFRTEDKDSEKIKVLQDVLTSDKARSLIEEKYKGIVIPTF"
     regulatory      complement(3980..4085)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00162"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="SAM riboswitch class I; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="S-adenosylmethionine"
                     /db_xref="RFAM:RF00162"
     gene            complement(4177..5163)
                     /locus_tag="ACGI5H_002937"
     CDS             complement(4177..5163)
                     /locus_tag="ACGI5H_002937"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889551.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipoate--protein ligase"
                     /protein_id="HFG9698634.1"
                     /translation="MLLIYNEKTNPYFNLAMEEYLLKNFDEDLFILWRNEPSIIVGKN
                     QNTLSEINLEYIKEYSIPVVRRQSGGGAVFHDLGNINFTFIACNNNNFSDFRRFTQPI
                     IDLLKTLDVNAEFSGRNDLLIDGKKFSGNAQYNYKNKVMHHGTLLFSSEINDLSKALK
                     VKPIKFEGKGIKSVKSRVTNISEHLHSKMDILEFKDAIMDYLSKTNTDNTNYCLSEHD
                     IKQIEKLTKSKYETWDWNFGNSPKYTLSNELKYSGGNVEFNLNVDKGIITSIKFFGDF
                     FGKCDVAFVENKLIGIRHEENALRNTLDSIEINDYFLGADTDILVSGILGVK"
     regulatory      5327..5503
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00168"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="Lysine riboswitch is most abundant in Firmicutes
                     and Gammaproteobacteria where they are found upstream of a
                     number of genes involved in lysine biosynthesis, transport
                     and catabolism; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="lysine"
                     /db_xref="RFAM:RF00168"
     gene            5647..7377
                     /locus_tag="ACGI5H_002938"
     CDS             5647..7377
                     /locus_tag="ACGI5H_002938"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420315.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0015297 - antiporter activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Na+/H+ antiporter NhaC family protein"
                     /protein_id="HFG9698635.1"
                     /translation="MRNKKINIIFLTTIMFIMSTVMVFAEEDIDTIALANAEKFGILT
                     LIPPLVAIILAFITKNVIISLLIGILSGSFIIKASGINVFATFIQAFLDLVDRALVSL
                     ADPWNAGIILQVLSIGGVINLVAKMGGAKAIAEALAKRAKSAKGTQLITWFLGLLVFF
                     DDYANSLIVGPMMRPVADKMKISREKLAFIIDATAAPVAGLAIISTWIGLEVGLIHDA
                     FESISIDVDAFGIFLNTIPFRFYNILILAFIVISALLLKEFGPMRKAEIKSRSRKISI
                     DLDEGVEELDDLAPKNGVKLSVWNAIIPIGTLIIVALASFYYSGYTSIMGGDDKALIQ
                     LFTNSPYSFEAIKEAFSASDASRALFQSALVASLVAIIMAVVKKIFTISEAIDVWIDG
                     MKSLVITGVILILAWSLSSVIKELGTAKFLIHLLSGSLPPFLLPSLIFGLGAIISFAT
                     GTAYGTMGILMPLAIPLAYSLNPDMSYVIVSTSAVLTGAIFGDHCSPISDTTILSSMG
                     AGCNHIDHVNTQMPYAIFTAVITIVFGYIPAGLGLPIYIVLPVAIAAIFVGIQIIGKK
                     VDEAEIELVE"
     gene            7487..7567
                     /locus_tag="ACGI5H_002939"
     tRNA            7487..7567
                     /locus_tag="ACGI5H_002939"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:7521..7523,aa:Leu,seq:tag)
     gene            7902..8417
                     /locus_tag="ACGI5H_002940"
     CDS             7902..8417
                     /locus_tag="ACGI5H_002940"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861286.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HXXEE domain-containing protein"
                     /protein_id="HFG9698636.1"
                     /translation="MEKYIWLFPLLFIFHDMEEIIGFGIWLKKNKSMLDKKYPFISKV
                     YENYSTEGMAFAVFEEFILCIIFCILTVITENQYVYLLWLGSFIAYTLHLVIHIGQSI
                     IIRKYIPSLITSIICLPISIWCISKSIYIVDCEMSTTILYSIIGIIIVALNLKFAQSL
                     IGKFTKWMSNI"
     regulatory      8909..9013
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00504"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="glycine riboswitch; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="glycine"
                     /db_xref="RFAM:RF00504"
     gene            9223..11697
                     /gene="gcvPA"
                     /locus_tag="ACGI5H_002941"
     CDS             9223..11697
                     /gene="gcvPA"
                     /locus_tag="ACGI5H_002941"
                     /EC_number="1.4.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420319.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004375 - glycine dehydrogenase
                     (decarboxylating) activity [Evidence IEA];
                     GO_process: GO:0006546 - glycine catabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="aminomethyl-transferring glycine dehydrogenase
                     subunit GcvPA"
                     /protein_id="HFG9698637.1"
                     /translation="MNELKRVSLYNIHKELGAKLVEFAGWEMPLEYEGINKEHEKVRK
                     SAGIFDVSHMGEVQIKGAESEKFIQNLVTNDISALKINDIIYTPMCYENGGVVDDLLI
                     YKFGEEDYLLVINAGNIDKDVAWIIKQSEGYNVDIKNISSEVSQLAIQGPKAEEILQK
                     ITDIDLNSIKFYKSIPSTKVCGCPCLVSRTGYTGEDGFEIYCKNKYVEIIWNEVLKVG
                     GEDICPAGLGCRDTLRFEAALPLYGHEINEHISPIEGGLSIFVKTNKESFIGKSILSK
                     EKESGAKRKLVGFEMQGKGMPRNGYDIRIGDKTVGFVTTGCASPTTGKILGMGIIDSE
                     YAKVGNEIGIAIRKKVVPAVIVKKPFYKKQYKKDNIILNKENKFSYIPATSEDKSKML
                     KVVGLNSVDELFSDIPEEVKLKRDLNLEIGKSELEVSKIVKRLSEENLSLEDLTCFLG
                     AGAYDHYIPSIIKHITSRSEFYTAYTPYQAEISQGTLQVVFEFQSMIAEITGMEIANA
                     SMYDGATAAIEACIMAMNQTRKSKIVVSKTIHPETLSVLRTYLQYKDCEIVEIDFCNE
                     YGTTDIEKLKASVDKDTACVLIQTPNFFGIIEEMEEIEKITHENKAMLIMSVDPISLG
                     VLKTPGEIGADIVVGEAQSLGNPLNFGGPYVGFLASKSKYTRKMPGRIVGQSLDVEGK
                     IAYVLTLQTREQHVRREKATSNICSNQALNALVASIYMATMGKEGFKEVGMQSMKKAH
                     YTYNKLVQTGKYKPIFKGKFFKEFAVQGNLNIETINDKLLEENILGGYNLEYNYPELK
                     NSTLLCVTEKRSKEEIDKLVGIMEGL"
     gene            11697..13154
                     /gene="gcvPB"
                     /locus_tag="ACGI5H_002942"
     CDS             11697..13154
                     /gene="gcvPB"
                     /locus_tag="ACGI5H_002942"
                     /EC_number="1.4.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861288.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004375 - glycine dehydrogenase
                     (decarboxylating) activity [Evidence IEA];
                     GO_process: GO:0006546 - glycine catabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="aminomethyl-transferring glycine dehydrogenase
                     subunit GcvPB"
                     /protein_id="HFG9698638.1"
                     /translation="MKEYNSLLIDISKKGRKAYSLPKLDIDDIKIENMIDQDMARQSE
                     LNLPEVGELELVRHYTLLSNKNFGVDTGFYPLGSCTMKYNPKINEDMAALPNFTGMHP
                     YQSSDTAQGSLSLMYDLSRRLAEITGMDEVTLQPSAGSHGEFTGLMIIKAYHENRGDH
                     KRTKVIIPDSAHGTNPASAAMANFDVIQIASDKNGAVDINALKEVLNDEVAALMLTNP
                     STLGLFEKNIKEIATLVHEAGGLLYYDGANMNAIMGITRPGDMGFDVVHLNLHKTFST
                     PHGGGGPGAGPVGVKKELVPFLPIPVIERKEDKYVLNYDREKSIGKIKNFYGNFGVLV
                     RAYTYILTMGRDGLKEASEMAVLNANYIKESIKDDYILPIDTLCKHEFVLGGLPRGEA
                     NIKTIDIAKRLLDYGYHPPTMYFPLIINEALMIEPTESESIETLDSFIEAMKSVAKEA
                     KEEPELLKTAPHNTLVKRVDDARAVKKPILTWSQR"
     gene            13577..15934
                     /locus_tag="ACGI5H_002943"
     CDS             13577..15934
                     /locus_tag="ACGI5H_002943"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893215.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0005215 - transporter activity [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="HAD-IC family P-type ATPase"
                     /protein_id="HFG9698639.1"
                     /translation="MDKVNLERYSCDINVGLNKNQLQSRIDDNLINAFDNGKTKTYKQ
                     IFKDNIFTLFNLINIVLVCLLVSVGSFKNTLFIFIAVINTIIGVIQEIRAKRLLDNLS
                     VIVSNKVSVIREKEKKEIDVQELVLDDIMILKTGNQICADSKVLNGKLEVNESLVTGE
                     SDIIIKNKGDFLYSGSFVVSGEAFVRVENIGKDNYANKIANDAKISKKHNSQLRNSLN
                     AILKIVGIIIIPLGIILFAKQHFGNGDSIATSVVGTVAAVNGMIPEGLTLLTSIALAV
                     GTIKLASHKTLVQELYCVETLARVDTLCLDKTGTITEGKMQVDDIVMLEEVDINEIMG
                     NICNSLKDDNATLNAIRDKYNVLDTYKAKNLIPFSSERKYSGVTFENKGTYLLGAFEF
                     IFKEKNKKLRIEVERYSKKGNRVIVLAHSDSYMEDNNIPEDIKPLAFILILDKIRDEA
                     KETLEFFYNEGVDIKIISGDNPITVSEVARKAGLKTASNFIDATTLKNDSDIYKAVDK
                     YSVFGRVSPQQKKQMILALKKQNHTVAMTGDGVNDVLALKEADCSIAMASGSDVTKNV
                     SNLVLLDSNFASMPKVVMEGRKVINNIQRASSLFLVKTIFSFFLSLLTLFFFSRQYPF
                     VPIQLSLIGAVTVGIPSFFLALEANKSRISGNFLLNILKNALPGALCVTVNVIIVYNI
                     VEYLGYSSSVFSTMCAILTGVCGLLILRQQCLPFNKERLFLIVSMTIAFVIGILFLGG
                     LFSFVALSRELILITMALAILMPIMIKVMLFVLDEILETIVPDLN"
     gene            complement(16020..16337)
                     /locus_tag="ACGI5H_002944"
     CDS             complement(16020..16337)
                     /locus_tag="ACGI5H_002944"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729474.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyrimidine/purine nucleoside phosphorylase"
                     /protein_id="HFG9698640.1"
                     /translation="MSEFKNVTAVKKANVYFDGKVSSRVIILPNGERKTLGLMLPGEY
                     TFSTREEEIMEMLAGSMDVKLPGSNEFVTYKEGQKFNVPSDSSFDLKVNEVVDYCCSY
                     IAD"
     gene            complement(16921..18192)
                     /locus_tag="ACGI5H_002945"
     CDS             complement(16921..18192)
                     /locus_tag="ACGI5H_002945"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889556.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="amidohydrolase family protein"
                     /protein_id="HFG9698641.1"
                     /translation="MLKVLKGNIIFTKTSETFTVFENSYIMLEKGKVKGIFKEIPKEY
                     KNLKVVDYTDKLIIPGMNDLHAHASQFKNLGMAMDKELLPWLETYTFPEESNYKDIEY
                     ATKMYKKFVKELWKSGTTRIAVFATVHKEASMKLMDIFKEVGLGAYVGKVNMNMNCPD
                     TLLENTQDSITDTEEIINKYSDTDSIVKPIITPRFIPSCTSELLKGLGDLCLKYNIPI
                     QSHLSENYDEIEWVRSLEPESKFYGDAYNRYNLFGQTPTLMAHCVHCSQDEIDLMREN
                     NVMAVHCPASNFNVGSGAMPIRKLIDNNIRLALGSDISGGHTLSIFKAMVSAIQLSKL
                     YWVNSGKKYNFLSLSEAFYIATKSGGSFFGKVGSFEEGYDFDALIIDDSNLNHDNYSI
                     LERLERFIYVGDDRNIIHRYVCGKLIEEPNI"
BASE COUNT         7245 a         2272 c         3046 g         6757 t
ORIGIN      
        1 tataaattat attaatagta ataatctata agaacttata tattagaaaa aaatttttgt
       61 atatataaag gactctaaag atgaactatg taaaacaagg tttatatatt ctaattgtat
      121 agaaaaattt attgtaaacg catgtatatt attagaaaaa atagtttgga ggtattcaat
      181 aaacataaaa aacaatatag gggataaagg tgttttatga agagattttt gaggagaatt
      241 atcttagttt tatttatttt gttgattttt ataagtttta tttctattaa attaattcat
      301 aatgttggag attatggaaa attgattaat tatgttggga ttgttcgtgg agctagccaa
      361 cgtctaacta aactagagat gaatcatcaa ccaaatgatg aattaataga atatattgat
      421 gaaatcctac aggagttgat tacagggcat ggagattatg gtttagtaat cactgattgt
      481 aatgaataca atgaggactt acttttatta gaaaaaaagt gggaagattt aaatattgaa
      541 attaaaaaag taagaatgaa agaacagaat aaccagttat taagtataag tgaagagttt
      601 ttttctcttg caaatgatac agtgtttaaa atagaaaact tttctaaaga aaaaagtaat
      661 tacttaatga ctttaataat aattatatct attataggta tattagcatg tatcatattg
      721 attttacaat atagtaaaaa aatggttaga ctggaaaaat taaatgtaga tttaaaaaat
      781 attgcatata aagatgaact aacaggagta aatactatag aaaaatttaa attggatgca
      841 aatcaaaata tttgtataca taaggataag aaatttgctg tattctatat tgattttgaa
      901 aactttaaat acattaatga tatatttgga tatgattatg gtgacatgat actgaaaaga
      961 tatgctaatc ttatgatgaa tgacataggg aaatatgaaa tatttgcaag agaaattgca
     1021 gatagatttg ttgcgttaag atgctatgta gataaggaag atttagtggt aagacaacga
     1081 gatgtagaca atgaactaat taatataaca aatgaaatta aaaataaaca tagtattact
     1141 gttgttagtg gaatttgttg tattgaagat gtaaatgaaa aattaagtat agatggttta
     1201 ataaatagag caaattttgc acaaaaaact gttaagaata aaccaggtac taattatgct
     1261 ttttataatg acagtattcg taaaaaaatg attgaagaaa atactatcaa aagtagaata
     1321 catgaagcta ttgaaaaaag agaatttata gtttatttac agcctaaagt taatttacat
     1381 agtcaaaaaa taaattgtgc agaagcttta gttcgttggc ttactccgga taaaggtatt
     1441 atatctccag caatatttat tccagtactt gagaagaatt tttttattgc cttagtagat
     1501 aagtatgttt ttgaggaggt ttgtaaatgg attagaaaga ggttagatga aaataaacct
     1561 tttgttcaga tatcagttaa tgtttcaaga atacaatttt ataacactaa atttgtagaa
     1621 acttattcca atatacaaaa taaatacagg atacctaaaa atactataga aattgaattt
     1681 acagagagtg ttgcttttga gaatcaaaaa catcttttgg aaattataca tgatttgcat
     1741 gaaaatggat ttacttgttc tttagatgat tttggaaaag gttattcgtc tttaagtgtt
     1801 ttaaaagatt taccatttga tgttttaaag cttgattcta tgtttttcaa ggctagttta
     1861 gataaagata aagagaaaat agtaataaaa aatattgtac atatgttaaa agaacttaat
     1921 atcacaactg ttgctgaggg cattgaatgc aaggaacaag ttgaatttct tagggatatt
     1981 gggtgtgatt tagttcaggg atttgtattt tataaaccaa tgccaatatt agaatttgaa
     2041 aaaatattgg ataaagagtt tgtttataat agctaaaatg tactttataa aatatgaact
     2101 aattaagtaa aattattttg tactgaataa atttttactt tatttacaga ataatgatta
     2161 tttacagaaa agcgcgaaaa gtgtattcct ttaagtgtgg gatggatagc acaaatagag
     2221 gagaaaaaat attggccata taagaatgca taataatata aatatttaaa aggtcagcat
     2281 tatataaaaa ttaaaaagaa aataaataat ttttctataa aaaagagact atgagaaaat
     2341 ttactcatag tctcctaaat aatgtattta ttttcttcct gcaacccatt ttaatcccca
     2401 atgaaattca gtatccattt ctctatgacc tttgaagtat ttaactactt tttcaacact
     2461 gaatgtctca tcatttacat tttctatcaa tgctattgaa cacatattat agccattttt
     2521 atgttcatca agtttgacaa ctaagtctga atcttgtttt tgtttgattg ttacaattcc
     2581 atcagcttca gaccagttag ctacaccttc gtatataaaa gcataaataa gtattctttt
     2641 tatatctttt attttattac catttattct taaattttct ccttgtgtat tacttcctgt
     2701 tctgtcatct ccatctaatt gagcaaaagg tggattgtct aaactaccaa aggcatttcc
     2761 taatgcttga acagcacctt ttacaccatt tttcatctca aataggcaac ccaaatctaa
     2821 atctatatta ctgcttctta aagagccaaa aaaacccttt ttttgtactt tttgattcca
     2881 atttaaatta actaaaattt cacctaaatc gctattttcc ttttttgtaa ggtttatttt
     2941 ttgtcccttt tttaattcta tagccatagt aatcttcctc cacaaacata gatttattta
     3001 aatggtagca cttaataagt caatattcaa caagattaga ataataatat taaaattata
     3061 ctaaatatac taaaaagtag gaatcacaat acctttgtat ttttcttcaa ttaagcttct
     3121 tgctttatct gatgtaagaa catcttgtag aactttaatc ttttcactgt ctttatcttc
     3181 agttctaaat gctaaaagat ttgcatactc gtcatttata ggagctgtat aaattccgtt
     3241 tttcttggca tcaagaccag caggtacagc ataagtagta tctataaatg cagcagtcac
     3301 atctggaaga gaagatggaa tttgagcaat atctaactct ttgaattgta ttccctttgg
     3361 attttctatt atgtccttag gactaactaa tccatcccct ttaggtaacg ttaaaagtcc
     3421 aatactttca aggtatctaa ggttcttaga acaagaagat gggttattgc ttattgcaat
     3481 tgtatctcct tttttaaatt catcaacaga ttttatctta taagagtaaa gtattgctgg
     3541 gcatacatat agttttttac cagccattat tttgtaacct ttggccttaa cagcttcttt
     3601 tagataaggt tcatgttgaa atagatttgc atcaatttca ccattattta aagcttcgtt
     3661 tggaagtatg taatcatcaa agtttttaac ttctaaagta tatccttttt ctttaataag
     3721 tggttttaat tcttctaata actctcctcc tggaactaaa gtagcaccaa caacaatttt
     3781 tttatcatct ttagctttag aacatccaac cacagctaaa gttagtacta gacataataa
     3841 caaacataat aattttttga atttcatata aattccctcc tgaatataat tgattagtta
     3901 aaaataaaat accattcttt atcacactgc aaaataaaaa taagcctgag tttaaactca
     3961 ggctttaaaa gctaatttag actcatcttt cagtataata ctgcaggatt tagcaccaat
     4021 gtatataaaa atatactggt tgctgggttt catagggcca gtcccttcac cactctggat
     4081 aagaagtatc aatttttaat tatgttataa atattatcat gattttttac gtctgtaaac
     4141 ataattttat aaatatttta aaatctttaa tgtattttat ttaacaccta aaattccaga
     4201 aactagaata tcagtatcag cacctaagaa atagtcattt atttcaatag aatccagagt
     4261 atttctcaaa gcattttctt catgccttat accaataagt ttattttcta caaatgcaac
     4321 atcacatttt ccaaaaaaat ctccaaaaaa ttttatacta gttattatgc ctttatcaac
     4381 atttaaatta aactcaacat ttccaccaga atattttaat tcatttgaaa gagtatattt
     4441 tggtgaatta ccaaaattcc aatcccaagt ttcgtatttt gatttagtaa gcttttctat
     4501 ttgttttata tcatgctcac tcaaacaata attagtatta tcagtatttg ttttagaaag
     4561 ataatccatt atagcatctt taaattctaa tatgtccatt tttgaatgta aatgttcact
     4621 tatattggtt acacgagatt ttacagattt tattcctttt ccttcaaatt ttataggttt
     4681 aacctttaat gcttttgaga ggtcatttat ttcagatgaa aataaaagag tcccatgatg
     4741 cattactttg tttttgtagt tgtattgagc atttccagaa aatttcttgc catctataag
     4801 aaggtcattt cttccagaaa attcggcatt gacatctagt gttttaagta aatctattat
     4861 gggctgagtg aatcttctga aatcactaaa attattattg ttacaagcta taaatgtaaa
     4921 atttatattt cccaaatcat gaaatacagc tccaccacca gactgtctcc taacgacagg
     4981 tatagaatat tcttttatat attctaaatt tatttcagaa agtgtgtttt ggttttttcc
     5041 aacaattata gaaggttcat tcctccataa aataaataag tcttcatcaa aattttttag
     5101 aagatattct tccattgcta aattaaaata agggtttgtt ttttcattat aaattaataa
     5161 cattaaagta gttcctccat agaattgata aaatttttat tatgaataca attaatttta
     5221 taattcgaca ataatataaa aactccttta aattagaaat tttaaaaact accttgcaaa
     5281 gtttaaataa ataatatata ctcaaaatat gtttaataaa agtgaataga agggtagagg
     5341 cgcaataatc tatcagtact aataaggagt taagcacaga gagttattag gaaaggagat
     5401 attgccgaag ttttataatc gatgctttaa gattatattg ctgggggtac atagaaaata
     5461 tgtacaactg tcacaggttt atttgtggtg agctatcatt taaggaatta tattatattt
     5521 atttttacta ttgttgatat attgtaatgt ttaagccttg agtgtttacc actcaaggct
     5581 tttttagttt tattgtaaca taataccctg tacagttcac aaaattaaaa ggagagggag
     5641 atttatatga ggaacaaaaa aattaatatt atttttctga cgacaatcat gttcataatg
     5701 tcaacagtaa tggtttttgc agaagaagat atagacacta ttgcactagc caatgcagaa
     5761 aaatttggga ttttaacttt aataccacca ttagttgcta taatactcgc atttataact
     5821 aaaaacgtaa taatttcttt acttataggt attctttctg gtagttttat aattaaagct
     5881 agtggtatta atgtttttgc gacatttata caggcatttt tagatttagt agatagagct
     5941 ttagtatctt tagcagaccc ttggaatgcg gggataatac tacaggtttt gtcaattgga
     6001 ggagtaataa atcttgttgc taaaatggga ggagctaaag ctatagctga agcacttgct
     6061 aaaagagcaa agtcagcaaa agggacacag cttataacat ggtttttggg gcttttagta
     6121 ttctttgatg attatgccaa ttcactaata gtaggtccta tgatgagacc tgttgcagat
     6181 aaaatgaaaa tatcgagaga aaagctagca tttataatag atgccacagc agcaccagtt
     6241 gctggtttag ctataatatc tacatggata ggtcttgagg ttggtttaat acatgatgct
     6301 tttgaaagta taagtataga tgtagatgca tttggtatat ttttaaatac aataccattt
     6361 agattttaca atatattaat attagctttc attgtaatat cagcattatt attaaaagaa
     6421 tttggtccaa tgagaaaagc tgagataaaa tctagaagta gaaaaattag tatagacctt
     6481 gatgaaggcg tagaagagtt ggatgattta gctccaaaaa atggagtaaa attgagtgta
     6541 tggaatgcta taatcccaat aggaacattg ataatagttg cattagcatc attttattat
     6601 agtggatata catctataat gggaggagac gataaggctc tgatacaact atttacaaat
     6661 tctccatatt cttttgaagc aataaaagaa gcatttagtg catctgatgc atctagagca
     6721 ttattccagt ctgcacttgt tgcaagttta gttgctatta taatggctgt agtaaaaaag
     6781 atttttacaa tatcagaagc aattgatgtt tggatagatg gaatgaaaag tttagtaatc
     6841 actggtgtaa tattaatact tgcatggtca ttaagttcag taataaaaga gttaggtaca
     6901 gctaaatttt taatacacct actatcaggt tcactaccac cattcttatt accaagttta
     6961 atatttggtt taggagcaat aatatctttt gctactggaa cagcttatgg aacaatgggt
     7021 atacttatgc cacttgcaat tccattagca tactcattaa atcctgatat gtcttatgta
     7081 atagtaagta ctagtgcagt tttaacaggt gcaatatttg gagaccattg ttctccaatt
     7141 tcagatacaa caatactttc ttcaatggga gctggctgta atcatataga ccatgttaac
     7201 actcaaatgc catatgctat atttacagca gtaatcacta ttgtatttgg gtatatacca
     7261 gctggacttg gattgccaat atatatagta ttaccagtgg caatagctgc tatatttgta
     7321 ggtattcaaa taattggtaa gaaagttgat gaagcggaaa tagaacttgt agaataaaga
     7381 tataaataag tttcaccttt tattatcact attttgttag tttttagata attttaaaaa
     7441 gttattgaaa ataatggcga aatatagtaa aataaaagag tgataagcgg atgtggcgga
     7501 attggcagac gcactagact taggatctag cgccattggc gtgggggttc gactcccttc
     7561 atccgcactt tacagtactt aattgtactg aaaaaaactg gggttgctgg ctttcggagt
     7621 gggctatccc gtttttattt ttttgtatat ataatagatt ggcactttag tataaggtgc
     7681 tttttttata ggcaaaaaca gtacatttat ttctgtttta ttatcattca tctattagaa
     7741 tatactttag ttaagaatgt gttaataagc agtgttcaca ttcttgataa aatgtggaat
     7801 aatatgtatt tttactaaga cggaaatgaa ataattaaac cattaaataa tattataaga
     7861 tgatgaataa gtagataaat caaattttgt aggaggatat tatggaaaaa tatatatggt
     7921 tgtttccatt actttttatt tttcatgata tggaagagat aataggtttt ggaatatggc
     7981 ttaaaaaaaa taaatcaatg cttgataaga agtatccatt tatcagtaaa gtttatgaaa
     8041 attatagtac tgaaggcatg gcatttgctg tgtttgaaga atttatttta tgcattattt
     8101 tctgtatact tacagttata acagagaatc agtatgtata tctactatgg ttaggtagtt
     8161 ttatagcata taccttacat ttggtaattc atatagggca gtcaatcata ataagaaaat
     8221 atataccttc acttattacc agtatcatat gcttaccaat aagcatttgg tgtataagta
     8281 agagtattta tatagttgat tgtgaaatga gtacaacaat tctgtacagt ataattggca
     8341 ttataattgt agcattgaat ttaaagtttg cacagtcgct gattggaaaa tttacaaagt
     8401 ggatgtcaaa catataaatt ttagtttatt ggacagttca aggaatcaga aattggaatt
     8461 ttatagtatt aatattttat ggtattaata taatgtataa aattttatag caatgtattt
     8521 cataagtata aagtgactag aattttaaga aatatacaaa ttctataaaa actaaataat
     8581 ttcaagtata ttttaaaaat cttatttttc acaagtttaa aattgtaaac gatttcatca
     8641 agtctatgaa tatactttta acatgttata gtaaatctca atataaattt acatttggtt
     8701 ctttgtgtgt tattttaata ataaattaag tgaaaatgtt attttacatt aatatataat
     8761 atctttgcat aagagtgaat aatataaaag agaaataatt gataataaaa acttaacaaa
     8821 aaaattaata cataaaaaaa aataaatata atgtgttgac atttaattga aatattcata
     8881 caataaaatt gaaaataaat atttccaaat gagattagcg agagagtcct ttatacgaaa
     8941 aggcgccgaa gaagaaattt aagaaatgcc aatttttaga gaagctttca ggcaaaaata
     9001 tcgctaattg atgggactct ggagagactt aagttaagat actataagtc accgaagaag
     9061 caaaataata ttaaattatt aaatctttca ggtatacaaa cagggatata taggctagga
     9121 ttattttcca tgctgatata tctttttttt atgaaaaagt acaggaaata atatcaaagt
     9181 tacttaaata cagtaggtct aattttctag ggagggttat atatgaatga attgaaaaga
     9241 gtatctttgt acaatataca caaagagctt ggagcaaaac ttgttgaatt tgctggttgg
     9301 gaaatgcctt tagaatatga gggtataaat aaagagcatg agaaggtcag aaaaagtgca
     9361 ggtatatttg atgtatctca tatgggagag gtacagataa agggagcaga gtcagaaaaa
     9421 tttatacaaa acctagttac aaatgatata agcgcattaa agataaatga tattatatat
     9481 acacctatgt gttatgaaaa tggtggagta gttgatgatt tattaatata taaatttggt
     9541 gaagaagatt atttattagt aataaatgca ggtaatatag ataaagatgt agcatggata
     9601 ataaaacaaa gtgaaggata caatgtagat ataaaaaata tatctagtga agtgagtcaa
     9661 ttagcaattc aaggacctaa agcagaagaa attcttcaaa aaatcacaga tatagactta
     9721 aactcaataa aattttataa gtcaattcca tcaacaaaag tatgtggttg tccttgttta
     9781 gtttcaagaa caggatatac tggggaagat gggtttgaga tatactgtaa aaataaatat
     9841 gtagaaataa tttggaatga agttctaaag gttggaggag aagatatatg tccagctggt
     9901 ctaggttgta gggatacttt gagatttgaa gcagctctac ctctatatgg acatgaaata
     9961 aatgaacaca tatctccaat tgaaggtggt ttatctatct ttgtgaaaac aaataaagaa
    10021 tcatttattg gcaaatcaat tttatcaaaa gaaaaagaaa gtggagctaa aagaaagtta
    10081 gtaggatttg aaatgcaagg taaaggaatg cctagaaatg gatatgatat aaggattggt
    10141 gataaaacag ttggatttgt aacaacagga tgtgcatctc caacgacagg aaaaatttta
    10201 ggtatgggaa ttatagattc tgaatatgca aaagtaggaa atgaaatagg tatagcaatc
    10261 agaaaaaaag ttgttcctgc tgtgatagtt aagaaacctt tttataaaaa acaatataaa
    10321 aaagataata ttatattaaa caaagaaaat aaattttcat atatacctgc tacaagtgaa
    10381 gataaatcaa aaatgttaaa agtagttgga ttaaattcag ttgatgaatt attttcagat
    10441 ataccagaag aagtaaaatt aaaaagagat ttaaatttgg aaattggaaa atctgaatta
    10501 gaggtaagca aaatagtaaa aagattgtca gaagaaaatt taagtttaga agacttgact
    10561 tgttttcttg gtgctggtgc atatgaccat tatataccat caattataaa acatataact
    10621 tcaagatctg aattttatac agcatatacc ccatatcaag ctgaaataag tcagggaact
    10681 ttacaagtag tttttgaatt tcaatctatg attgcagaaa ttacaggtat ggaaattgca
    10741 aatgcatcaa tgtatgatgg agcaactgct gcaatagaag catgtataat ggcaatgaat
    10801 cagactagaa aaagtaaaat agtagtgtca aaaactattc atcctgaaac tctgtcagta
    10861 ttaagaactt acttacaata taaagattgt gagatagtag aaattgactt ttgtaatgaa
    10921 tatgggacta cagatataga aaaattaaaa gcttctgtag acaaagatac agcatgtgtt
    10981 cttatacaaa ctcctaattt ctttggaatt attgaagaaa tggaagaaat agaaaagata
    11041 actcatgaaa ataaggctat gttaattatg agtgtagacc caatatcatt aggagtttta
    11101 aaaacaccag gtgagatagg tgcagatatt gttgttggag aagctcaatc acttggaaac
    11161 cctcttaatt ttggaggtcc ttatgtagga tttttagcta gcaaatctaa atatactaga
    11221 aaaatgccag gaagaatagt tgggcaaagt ttagatgtag aaggtaaaat tgcatatgta
    11281 ttaactttac aaactagaga acagcatgta agaagagaaa aagcaacttc taatatatgt
    11341 tcaaatcaag ctttaaatgc tcttgtagct tcaatatata tggctactat gggtaaagaa
    11401 ggatttaaag aggttggtat gcagtctatg aaaaaagcac attataccta caataaactt
    11461 gtacaaactg gaaaatataa gccaatattt aaaggtaagt ttttcaaaga atttgctgta
    11521 caaggaaatc ttaatataga aactataaat gataaactct tagaagaaaa tatattagga
    11581 ggttataatt tagaatacaa ttatccagaa ttaaaaaatt caactttgct ttgtgtgact
    11641 gagaaaagaa gcaaagagga aatagataag ttagttggaa taatggaggg attataatga
    11701 aagaatacaa tagtttgttg atagatatat ctaaaaaagg taggaaagca tactcacttc
    11761 caaagttaga tatagatgat ataaaaatag aaaatatgat tgaccaagat atggcaagac
    11821 aaagtgagtt gaatttgcca gaagttggtg aattagaatt agttagacat tatacattat
    11881 tatcaaataa aaactttgga gttgatacag gtttttatcc tttgggttct tgtactatga
    11941 aatataatcc taaaataaat gaagatatgg cagcacttcc aaactttact ggaatgcatc
    12001 cataccaatc ttcggataca gctcaaggtt ctctttcttt gatgtatgat ttatcaagaa
    12061 gacttgcaga aattacaggt atggatgaag ttacactaca accttcagca ggttctcatg
    12121 gtgagtttac agggcttatg attataaaag catatcatga aaatagaggt gaccataaga
    12181 gaaccaaagt gataattcca gattctgcac atggaacaaa tccagcaagt gcagctatgg
    12241 caaactttga tgtgattcaa atagcatctg ataaaaatgg agctgtagac ataaatgcat
    12301 taaaagaggt tttgaatgat gaagtagcag ctcttatgct tactaatcca agtactcttg
    12361 gtttatttga aaaaaatata aaagaaatag ctactcttgt acatgaagca ggaggacttt
    12421 tgtactatga tggtgcaaac atgaacgcta ttatggggat aacaagacct ggagatatgg
    12481 ggtttgatgt ggttcatctt aatcttcata agactttttc aactcctcat ggaggtggag
    12541 gtccaggagc tggtcctgtt ggagttaaaa aagaattagt acctttttta ccaataccag
    12601 taattgaaag aaaagaagat aagtatgtac taaattatga tagagaaaaa tctattggga
    12661 aaattaaaaa tttctatggt aattttggag ttcttgtaag agcttacaca tatatactaa
    12721 ctatgggaag ggatggactt aaagaggcta gtgaaatggc agttttaaat gctaattata
    12781 taaaggaaag tataaaagat gattatattt tgccaataga taccttgtgt aagcatgagt
    12841 ttgtattagg tggattgcca agaggagagg ccaatataaa aactatcgat attgcaaaaa
    12901 gactactaga ttatggatac catcctccaa caatgtactt tcctcttatt ataaatgagg
    12961 cacttatgat agaacctaca gaaagtgaga gtatagagac attagatagt tttatagaag
    13021 ctatgaaaag tgttgctaaa gaggcaaagg aagaaccaga actattgaaa actgctccac
    13081 ataatacttt ggtcaaaaga gtagatgatg caagggcagt aaagaaacct atactaacat
    13141 ggtcacaaag ataaatagtt aaaaagtaga gatttaaagt ataaagagaa ttaaatttgt
    13201 aagaaaaagc tatctaactt aatctagttt agatagcttt tttgtatatt agtatgtatg
    13261 gtattttcta tataaagttt taaattatat tagtgcttat atagaatatt gatatgatga
    13321 ttatgtatag atattaataa gaattgttga atttatcttg ccttaacttt atttactctt
    13381 ttatattaag aaaaacttaa ctaaaatata gcgaaattca taaaaattta ggaaatctta
    13441 agaattataa tatttaaatc tttagattta tattttatta tataaactat agaataataa
    13501 aataaaaaaa ttgagaattt tataatatat ttgtagattt gagtataaaa aagtgctaag
    13561 ttgaaaggag taaaatatgg ataaggttaa tttagaaagg tatagttgtg atataaatgt
    13621 tggtttaaat aaaaatcaac ttcaaagtag aatagatgat aatttaatta atgcatttga
    13681 taatggaaaa accaaaacat ataaacaaat ttttaaagac aatatattta cactttttaa
    13741 tctcataaat attgttttag tctgtttatt agtttcagtt ggttctttta aaaatacctt
    13801 atttatattt attgctgtaa ttaatactat tataggagta atacaagaga taagagctaa
    13861 aagattattg gacaatctat ctgttatagt ttcaaataag gtatctgtca taagagaaaa
    13921 agagaaaaaa gagattgatg tacaagaatt agtattagat gatattatga ttttaaaaac
    13981 aggtaatcaa atttgtgcag attcaaaagt tttaaatgga aaattagagg taaatgagtc
    14041 tttggttaca ggtgaatctg atattattat aaaaaataaa ggcgattttt tatattctgg
    14101 aagttttgta gtttctggag aagcttttgt aagagttgaa aatataggaa aagataacta
    14161 tgcaaataag atagctaatg atgcaaagat ttctaaaaaa cataattctc aacttagaaa
    14221 ttcattaaat gcaatattaa aaattgtagg tataataata attcctttag gaattatatt
    14281 gtttgcaaaa caacattttg gaaatggaga ttctatagct acatctgtag taggtacagt
    14341 ggcagctgta aatggtatga taccagaggg attaacatta cttacgagca ttgctctagc
    14401 tgtaggaact ataaaacttg ctagtcataa aactttagtg caagaactgt actgtgtaga
    14461 gactcttgct agagttgata cactatgtct tgataagaca ggtacaatta cagaaggtaa
    14521 aatgcaagtt gatgatatag taatgttgga agaagtggat attaatgaaa taatggggaa
    14581 tatatgtaat tctctcaaag atgataatgc aacactaaat gcaataagag ataagtataa
    14641 tgttttagat acgtataaag ctaagaattt aataccattt tcttcagaaa gaaaatacag
    14701 tggggttacc tttgaaaata aaggtacata tttattaggt gcatttgaat ttatatttaa
    14761 ggaaaaaaat aaaaaactta ggatagaagt tgaaagatat tctaaaaaag gaaacagagt
    14821 aatagtttta gctcatagtg attcttatat ggaagataat aatattcctg aagatataaa
    14881 gccactagct tttatattga tattggataa aattagagat gaagctaagg aaactttaga
    14941 atttttttac aatgaaggtg tagatataaa aattatatct ggtgacaatc ctataacagt
    15001 aagtgaggta gctagaaaag caggtcttaa aacagctagt aattttattg atgcaacaac
    15061 acttaaaaat gatagtgata tatacaaagc agttgataaa tacagtgttt ttggaagggt
    15121 aagcccacaa cagaaaaaac aaatgatttt agcattaaaa aaacaaaatc atacagtagc
    15181 tatgactgga gatggtgtaa atgatgtgct agcacttaaa gaagcggatt gtagcattgc
    15241 catggcatct ggaagtgatg ttactaagaa tgtgtctaat ttagtcttat tagattcaaa
    15301 ctttgcatca atgccaaagg ttgttatgga gggaagaaaa gtaattaata acattcaaag
    15361 agcatcttct ttgtttttag taaagacaat tttttcattc ttcttgtcgt tattaacatt
    15421 attcttcttc agtagacagt atccatttgt tcctatacaa ttatcactca ttggggctgt
    15481 aacagtgggt ataccatcat tcttcttagc tcttgaagca aacaaaagta gaatttcagg
    15541 aaatttttta ctcaatatat taaaaaatgc tttaccagga gcactatgtg tgacagtaaa
    15601 tgtaattatt gtttacaata tagttgaata tttaggttat agttcaagtg tattttccac
    15661 aatgtgtgct atattaactg gtgtatgtgg tcttttaata ttaagacaac aatgtttgcc
    15721 atttaataaa gaaagattat ttttaatagt aagtatgact attgcatttg ttattgggat
    15781 tctattttta ggtggattat tctcatttgt agcattgagt agagaattaa ttctcataac
    15841 tatggcatta gcaatattaa tgccaattat gataaaagtt atgttatttg tcttagatga
    15901 gatattagag acaattgttc cagatttaaa ttaattttaa aatgatataa ataagagcag
    15961 ttttagttga actgctcttt ttagatgtgt ttaattttat gtaagaatat gtatttttat
    16021 taatcagcta tatatgagca acagtagtca acaacttcat taacctttaa gtcaaaactt
    16081 gaatcactag gaacattaaa tttttgccct tctttataag ttacaaactc attgcttcca
    16141 ggcagtttta catccatact tccagcaagc atctccatta tttcttcttc tctagtagaa
    16201 aaagtgtatt ctcctggcaa cattaatcct aaagtttttc tttctccatt aggcagtatt
    16261 attactctgc tacttacctt accatcaaaa taaacgtttg ccttctttac tgcagtaaca
    16321 ttcttaaatt cactcattag ataaaacctc caaaattatt tgtacatata tattatataa
    16381 aaataatgta aaaaatgcta tatatttaca aaaaaattta gtatttatta aaaaaattaa
    16441 taagaataaa aaagagatga aattgcttaa attgataaaa aatataaaat aaattgcaaa
    16501 gtaagcaaga aaagaataag ttgaagagtt atatattata aatattaaaa attttagtat
    16561 taataaaaaa gatattacat taatatgaaa atataggaga ttagaagtgt ttgataatta
    16621 cagtacatgt tagatatatc attgtaaatt aacatagctt tgaatataat aatgttcaga
    16681 aggcaatatt tttgaggtct gaatccaata ataatatagt cttatgattg tagatatcaa
    16741 aaaatgtaag ttactaggaa tacgttttgt agatttatat atgattaata actaaagcta
    16801 taaataaaca aaataaaaag agtatgtttc aacctatagc ttttagattt aaaatatact
    16861 cttttattaa ttatagttgt ataaattaac cataatatat aattaaaatt tttattataa
    16921 ttatatatta ggttcttcaa ttagttttcc acatacatat ctatgaatga tatttctatc
    16981 atcaccaaca tatataaatc tttcaagtct ttcaagtata gaataattgt catgatttaa
    17041 atttgaatca tcaataatca atgcatcaaa atcataacct tcttcaaagc taccaacttt
    17101 tccaaagaaa cttccaccac ttttggttgc aatataaaaa gcctcagata aagataagaa
    17161 attatacttc ttaccagagt taacccaata taatttagat aattgtattg cagataccat
    17221 tgctttaaat attgacaatg tatgtccacc acttatatct gatccaagtg ctaatctaat
    17281 attattatcg attaattttc tgataggcat agcaccacta ccaacattaa agttagaagc
    17341 tggacagtga actgccataa cattattttc tctcattaaa tctatttcat cctgagaaca
    17401 atgaacacaa tgagccatta aagtaggagt ttgaccaaat aaattatatc tattatatgc
    17461 atctccatag aatttagatt caggttctag acttctaacc cattcaatct catcataatt
    17521 ttcagataag tgtgattgaa taggaatatt atattttaaa cataaatctc ctaaaccttt
    17581 taaaagttca cttgtacagc ttggtataaa tctaggtgtt attattggtt ttacaataga
    17641 atctgtatca ctatacttat ttataatttc ttctgtatca gtaatagaat cctgagtgtt
    17701 ttctaataaa gtatcagggc aattcatatt catatttact ttaccaacgt atgctccaag
    17761 accaacttct ttgaatatat ccataagttt catagaggct tctttatgta ctgttgcaaa
    17821 cactgctatt cttgtagttc cagatttcca aagttctttt acaaattttt tatacatttt
    17881 tgttgcatat tctatatctt tataatttga ttcttctgga aatgtataag tttcaagcca
    17941 tggcaaaagc tctttatcca tagccattcc aagattttta aattgagagg catgggcatg
    18001 gaggtcattc ataccaggta ttataagctt atcagtgtaa tctactactt ttaggttttt
    18061 gtattcctta ggtatctctt taaatattcc ctttacttta cctttttcca gcataatata
    18121 actattttca aatactgtga aagtttctga agtttttgta aaaattatat ttccttttag
    18181 tacttttaac atataggtct ccttagtttt aaatttgttt taatatatgt aggtaaaatt
    18241 ttgttttaca aatcaaaatt ttaccacatg tattatatca aatctaaact ataaatacta
    18301 ttagataata gcaaatatta gtgaaataca gttgtttact attattatat ataactgaca
    18361 tttaagtgac atttaagaaa aatataatgc ctacttacat aaaatggaat gttatttaaa
    18421 gagaactttg attatatttt cagaagtttt tttatccata tcgtttaaaa caagaaaata
    18481 tctattcata gttattttta tattagtatg tcctaatctt tcagagatga tttttatatt
    18541 agttctagct agaagaagaa ctattagaat agataatata gtaagtattt acaaatatgt
    18601 aggtgttctt aaattgataa attattccat tttaatttta tagtttgaat tttatgatat
    18661 aataaaaata tataaatttt gcagtgagcg atatttttga taaagtaggg tttaacagtt
    18721 gcaatgtaag ggattgaggg tgtatgataa atgttatcaa ttgcactact catggttcac
    18781 tgcaaatttg agagagttgt atgtgtgtaa gtactgaaaa tacttagttt attttggggt
    18841 tttatattaa ctaagtggta tgtaaataaa taatgtgttt tatcatcata actcctgcta
    18901 aacatgtttt atattaacta tgtggtatgt aaatcttgtt aatgcaaata aacaacatag
    18961 cactattaat agttttatat taactatgcg gtatgtaaat agggtttctg ataaaatctt
    19021 caaacatgta aaatatgtgt tttatattaa ctatgaggta tgtaaatctt atacttagtt
    19081 agaactatat atcgacacaa atatgcttta tattaactat atggtatata aattgcaatt
    19141 tttattcgtt gtccaatctc tttgaaattt gttttatatt aactaagtgg tatgtaaatt
    19201 tgtaacaagt ataggtaaaa taccccaata atttatacag cattttatcc tttaaaatat
    19261 aattattttt tatcatttgt agtaaataat taccagataa cattgacttt agttttaatg
//
LOCUS       DAYAOO010000077        19273 bp    DNA     linear   BCT 12-OCT-2024
DEFINITION  TPA_asm: Clostridioides difficile isolate ST8-SSI-h139-18
            SAMN40601845-rid21577343.denovo.077, whole genome shotgun sequence.
ACCESSION   DAYAOO010000077 DAYAOO010000000
VERSION     DAYAOO010000077.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN40601845
            Sequence Read Archive: SRR28438827
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 19273)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 19273)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-MAY-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-MAY-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002157583.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002157583.1
            Genome Coverage       :: 163x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/11/2024 16:19:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 4,038
            CDSs (total)                      :: 3,963
            Genes (coding)                    :: 3,930
            CDSs (with protein)               :: 3,930
            Genes (RNA)                       :: 75
            rRNAs                             :: 6, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 60
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 33
            CDSs (without protein)            :: 33
            Pseudo Genes (ambiguous residues) :: 0 of 33
            Pseudo Genes (frameshifted)       :: 7 of 33
            Pseudo Genes (incomplete)         :: 25 of 33
            Pseudo Genes (internal stop)      :: 11 of 33
            Pseudo Genes (multiple problems)  :: 8 of 33
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..19273
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN40601845-rid21577343.denovo.077"
                     /isolate="ST8-SSI-h139-18"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Denmark"
                     /collection_date="2018"
                     /collected_by="Statens Serum Institute"
     gene            complement(324..524)
                     /locus_tag="ACGI5H_002946"
     CDS             complement(324..524)
                     /locus_tag="ACGI5H_002946"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423171.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9698642.1"
                     /translation="MCFKTYVLKRVVNNNQLEITRSFDLDNLICTATEILKDNEIDLI
                     IIDEKNNVVWKNEKSTPQQENA"
     gene            complement(657..806)
                     /locus_tag="ACGI5H_002947"
     CDS             complement(657..806)
                     /locus_tag="ACGI5H_002947"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9698643.1"
                     /translation="MFKNKMDKCTHVLTAYISSSYDYYNFLDTQLDDFILEYGENVVS
                     LVYTK"
     regulatory      complement(860..957)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF01051"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="cyclic di-GMP riboswitch class I; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /bound_moiety="cyclic di-GMP"
                     /db_xref="RFAM:RF01051"
     gene            1166..1555
                     /locus_tag="ACGI5H_002948"
     CDS             1166..1555
                     /locus_tag="ACGI5H_002948"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009901721.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0045892 - negative regulation of
                     DNA-templated transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="BlaI/MecI/CopY family transcriptional regulator"
                     /protein_id="HFG9698644.1"
                     /translation="MKQQEVVNKLRRGELMLMEYLWRKNSILSKKEIIEAMKEKYKWR
                     KSTTEILLKRLVKMKTLKKKRIGFQFSYEVLVTKKEYLNAIKEDRKVTKYDSFFIRMF
                     TTMHKKEKMTEEQIKKYIENMEKIGKE"
     gene            1649..2032
                     /locus_tag="ACGI5H_002949"
     CDS             1649..2032
                     /locus_tag="ACGI5H_002949"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009901722.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0045892 - negative regulation of
                     DNA-templated transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="BlaI/MecI/CopY family transcriptional regulator"
                     /protein_id="HFG9698645.1"
                     /translation="MGFKKLPDSELKVMKFIWGLDGNKVASGEVVEAMKQIYDWNKNT
                     TLTILSKLAKKNYLYSQKTSKCTYYTIAVREKDYLKVETKKFFSFFHNNSLKSFFTAL
                     NDEENLSDDKLDMLEEWVKNWEEDE"
     gene            2750..4141
                     /locus_tag="ACGI5H_002950"
     CDS             2750..4141
                     /locus_tag="ACGI5H_002950"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729229.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="metallophosphoesterase"
                     /protein_id="HFG9698646.1"
                     /translation="MRNKIIIGITFLLVLLMSGCASKQTAEINVLATTDLHGVIPYEL
                     TSYVKEERKKDKNLTLVDAGDFFDSGEVFGSSMDSYFSARYKDGDNNTESYIETPISK
                     DMKEVGYDVAVLGNHEFISNNKFYLDNMISDFEKQKINILSANTYKKNGDSYTKPYII
                     KNINTPEGNVKLGILGLTIKEVGERKQWKDGKLVDSKSLELKDQEGYNGELYMNDLVE
                     DAKKWVSIMEKEKPDIIVAVAHTGEKPKKPKNPGNRIQDLAQQVDGIDAIVAGHNHVQ
                     IEQHDYKNKSGENVIVTEPGKHGECISKINFKLEKNNDKWNIVDKSSKLIKFEKNQES
                     DKFGEFISSINKVSKDKKEIRLSEVKTPEWDKIYVFKSGTSADDIYKTIGYKWRNISS
                     PKSDGMVQIVVMNNNKPVSYIYGEAEVMPINIKCDESEYKDNVVTIYPNKNDKFKIEK
                     GKQEYSINLKHIQ"
     gene            complement(4289..4597)
                     /locus_tag="ACGI5H_002951"
     CDS             complement(4289..4597)
                     /locus_tag="ACGI5H_002951"
                     /inference="COORDINATES: protein motif:HMM:NF015431.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR substrate-binding domain-containing
                     protein"
                     /protein_id="HFG9698647.1"
                     /translation="MLREQGSAIRDTLDSVLSLSNQKAYPVWESVNSFALIKAAQAGL
                     GITILPENLLLDSLLHKKLRLIELDGIDMENKMLAILHKDKNITQPLKIILDNISNVL
                     "
     gene            4634..5155
                     /locus_tag="ACGI5H_002952"
     CDS             4634..5155
                     /locus_tag="ACGI5H_002952"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420939.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chromate transporter"
                     /protein_id="HFG9698648.1"
                     /translation="MFSIGGGYAIIPLIQEKVVNQTGWISEKIFTDIITISQMTPGPL
                     AVNTSTFVGLQIGGFWGAVAATLGCVLCGVVISLFLYNFFQKHQNSTYIFEILNGLKS
                     ASLGLIISAAATIIILALFGTNKVYFNSIFEMLNWTALIIFFVTLLIVRKWKINPIVI
                     IIMSGILGIFFYL"
     gene            complement(5284..5520)
                     /locus_tag="ACGI5H_002953"
     CDS             complement(5284..5520)
                     /locus_tag="ACGI5H_002953"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9698649.1"
                     /translation="MLECFIAKDSKIKDGVNIPTLVFKTLHDRYFKTQYFDSYYNSLK
                     CKKKLVEINNVHNSYYIDSKKFCQEAYDWFVENQ"
     gene            complement(5830..9258)
                     /gene="uvrA"
                     /locus_tag="ACGI5H_002954"
     CDS             complement(5830..9258)
                     /gene="uvrA"
                     /locus_tag="ACGI5H_002954"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729233.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009380 - excinuclease repair complex
                     [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_process: GO:0006289 - nucleotide-excision repair
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="excinuclease ABC subunit UvrA"
                     /protein_id="HFG9698650.1"
                     /translation="MKINNYKNQSIITNPKKFENKYQDLPKTPIELLKVVQSLVIHGD
                     QGKLYGISFNKQQSDEELLRTIPQMLKRIFEINSNPLTIPRNPKQRLVGMCRDYSLLL
                     VSLLRYRGFEARMRAGFANYFESELTYEDHWLVEYYDTLTKRWIRIDAQIDDIQKNYF
                     QINFDTHDVGKTDGFLTGSEAWIRCRQGHAHPDDFGYNKNWKGWHSVKGNLLHDFNNM
                     IGLELLPWDLWTELSSKKYNQLTRAEKNLLDEMAEILSSGNIKIEALNLLIEKLPEDY
                     LKSIFSQLKILGISEIKELGNPLELEKKFKFTKAINKSIKNSLCHNKSSIYLKGGRQN
                     NLKDVEVTIPKNQITVITGVSGSGKSSLAFDTIYEEGKRRYFENLSNGAKLSEQLQKP
                     EFDLLQGLTPTIAIEQKKGSQNPRSTVGTLTSIWDYLRMLFVSIGKSYCPYCKIPLEK
                     KNNTKNYCPHCQTIFSKINTSTFNANSHTGACHDCNGLGFTYQVNPQLIVKDPTISIL
                     DGATYYFGKLRGKKPNGNWMVGELYAIAKDKNIDLDIPWNELPRDFIDAILYGTDDKI
                     YEFSFESKGRESKIRRPASGAINHIQRLFRESSSENNTLHQYMNKIPCNTCGGELLCI
                     EARFTTIKGYRFPELTKMTIEQLWNWLCELPNHLQKNELSLVNDILTELKIRVSYLLK
                     VGLSYISTDRTAPTLSGGELQRVRLSSQLGSELVGLTYILDEPSIGLHPRDHNLIIKM
                     IEELRDKGNTVIVVEHDKDTILSADYIIDVGPSAGTKGGFIIAEGTTQEIIKNPNSIT
                     GKYLSTYNKISSQNKIIPSKWLSLKGCHANNLKNIDVEIPLNCMCSITGVSGSGKSSL
                     VFHSLLPALEEKLKQKSIPDKNYTEFTGFDAIDDFILMDQAPIGKSSRSTPATYINIF
                     DEIRSLFAETPQAKQKLLDESYFSFNSKKGQCPNCQGLGKTKIILQYMADQWVTCSEC
                     QGKRYQKEILSIQYKGKTIADILDMEVAEAKTFFSDCSDIYRKLSLLDEVGLGYLKLG
                     QNTLGLSGGESQRIKLAKELGTKTKKRMLYILDEPTTGLHFKDIENLLITFRKLVNEQ
                     HSLLIIEHNTEVIRASDWIIDIGPDSGINGGEIVASGTPDEIKINPNSITGHFI"
     gene            9577..11811
                     /locus_tag="ACGI5H_002955"
     CDS             9577..11811
                     /locus_tag="ACGI5H_002955"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729234.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EAL domain-containing protein"
                     /protein_id="HFG9698651.1"
                     /translation="MKLSRYKKNSLVLSIILCSLIISILVITVFNTVKLHNISNKQSK
                     NYLNDVSTQIVMNVDSKIKFILSDLRIMADFIKQYEGDSRYEYLSKRKTSYKYYDVGI
                     IDLEGKAEFLSGKKFDLKNTVSYKKGIEGKEYSEVIESMGFVLYSVPIFNDNHEVSSI
                     LIGVSNKESMNEILNIDNFNGKGTIEIINSKGKPLFIGKNTELIKDLSHKYKSSGDEP
                     WAQKMLEDFKNDKSGNITITSSKGVQCLLTYHPITRGLNDWHFLLIVPEDAVLGELNK
                     LNSFTITMTFIITCIIGIITLILYIIRRKYVNQIENIAYLDSITNGINSTKFSMLVKP
                     LISESPDSTYMMIAMNIKDFKLINDCFGSEKGNMTLKHLYNILYKNIDENEEFVCRHD
                     ADLFYLLIKNRPVLEALELLYKIEADTNYFNKNRENPYFLRLSVGIYTIENHNEDLIT
                     IQDHANTARKSFNKTHQSDFSFYSDIERKRLISEKEISNLMEKALENKEFFMCLQPKI
                     DIKSGKISGAESLVRWKNSEKGIIYPSDFIPLFEKSGFICKLDLYILEETCKLISKWI
                     KEGKEVLRISVNVSRQHLNDKLFLEKYKHICNKYNVPTCLIDLELTESIFLENPEAID
                     IIEDIHSNGFKCSIDDFGFGYSSLGILKDFKVDIIKLDRSFFVSKNNIDRGKVVIKSI
                     IELSKRLGMKVTAEGIEELEQVEFLKNVGCDYIQGYVFSKPLLISDFENFAYENNKIK
                     NIHY"
     gene            12067..14097
                     /locus_tag="ACGI5H_002956"
     CDS             12067..14097
                     /locus_tag="ACGI5H_002956"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420949.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antiterminator"
                     /protein_id="HFG9698652.1"
                     /translation="MISGRMLLIMNFLKGKNKTSYKDISKQLSIEERKVRYDINNLNI
                     VLRSLNKSVIQKMNKGVLIIPDDFQVVCINNNEYVFSLTERVSIMKIISMFKIDNLNL
                     EKLSKEFQVSRSSIKNDLNVLSSELERNQITITYDKSFKISGEEDIIYKQRLNILKSY
                     SYLFGKEKSDLSVFEKYLVNVIEKIFKGIYLIDIYNWSMNLLLQMGWTLNDESFTWYV
                     SNIFLFTWYIHSDEKHPLESASLSEPCFENKFDQEFETIIQKKLTKEQIFLLKSFVFF
                     TNKYASLNEDMDLISTEIIVQDLIYNMSEILEISFKEDMILYKGLLNHIAPLIERIKQ
                     NIQIYEELLHVIPDKYQYVLEATKVSIQKNRVLSQIKNENETILLAIHFLGSIHRNER
                     NNYKNILLVCGFGYGVIAMLKDSLVNDYQINIVESIPSYKLQDYKEWESIDFIITTSK
                     IVIDLPKTIIEINPFLQEEDYLKFEEKGIKRKNVLTNYMSIKKRLDFLEEDAQKRVLS
                     IICQELGYSDERILFRQLNLSDLIGIDTIRIIDGDMKWEDAVKISSNILANCDFVSAQ
                     YAENIIDILKNVGFYAVKDNEFALLHGNDSSLVKVSSISLLICKEAVSFGDKKVKIIF
                     CLASRDKKEQIPAIINLTKMVYKTNFIAMLESAKTKEEAEVLIHKYEKEVTV"
     gene            14094..14546
                     /locus_tag="ACGI5H_002957"
     CDS             14094..14546
                     /locus_tag="ACGI5H_002957"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888039.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:1902495 - transmembrane transporter
                     complex [Evidence IEA];
                     GO_function: GO:0016301 - kinase activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA];
                     GO_process: GO:0016310 - phosphorylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HFG9698653.1"
                     /translation="MNKLVNVKCSFKIHVNSKEEAIISLVDVVSKEGYLIDKNQFLKD
                     VLKREETLSTYIGHGIGLPHSQSVGVKNSCITIGKLDTPIEWTEEGEKVDLIFLISVT
                     KDNENNLHLKILSKLARLLMHESFRNQIRCSDEQTVYNLIKEKIEEED"
     gene            14548..15603
                     /locus_tag="ACGI5H_002958"
     CDS             14548..15603
                     /locus_tag="ACGI5H_002958"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435041.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS fructose transporter subunit EIIC"
                     /protein_id="HFG9698654.1"
                     /translation="MRILKFLQKHLMTATSYMIPFVVAGGILFALSVTLSGQAAVPET
                     GWLAKLNQIGAAGLALFIPILGGYIAFSMADKPGLAPGMIGAYLAKEVNAGFIGGIIA
                     GFIAGFVVLQLKKIKLAPTMRTLGSIFIYPLVGTLITGGIIVFLIGEPIASFMTWMTN
                     WLNGMSGVSKIPLGGILGGMIASDMGGPINKVAATFAQTQVDTLPYLMGGVGVAICIP
                     PIGLGLATLLFPKKFSKEERDSGKASLLMGCVGITEGAIPFATSDPVRVIPCIMAGSI
                     VGNIMAFLLGCLNHAPWGGLIVLPVVDNRLGYIASVLTGAVVVAVLMKLVKKDVKEDE
                     EIEEDLDESIELIFEEL"
     gene            15670..15978
                     /locus_tag="ACGI5H_002959"
     CDS             15670..15978
                     /locus_tag="ACGI5H_002959"
                     /EC_number="2.7.1.202"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425302.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0022877 -
                     protein-N(PI)-phosphohistidine-fructose phosphotransferase
                     system transporter activity [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS fructose-like transporter subunit IIB"
                     /protein_id="HFG9698655.1"
                     /translation="MKIVAVTSCPSGVAHTYMSAESLELSAKKFGIEIKVETQGSSGI
                     DNELSLKDIDEATCVILTNDVEIRNMERFKGKKVVRMSVSEIIKKSDALIKKIKDTFQ
                     "
     gene            16082..17347
                     /locus_tag="ACGI5H_002960"
     CDS             16082..17347
                     /locus_tag="ACGI5H_002960"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895305.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="class II D-tagatose-bisphosphate aldolase,
                     non-catalytic subunit"
                     /protein_id="HFG9698656.1"
                     /translation="MKKLPIKTVVQRLLNLQEEGKSATLLGIGPMSPNLLQASFELAK
                     DDDFPLMFIASRNQVDADELGGGYVNGWNQETFTKDIKKVADKVGFDGLYYLCRDHGG
                     PWQRDKERNDHLPVDEAMELGKKSYLADIEAGFDLLMIDPTKDPFEIGKVIPLDVVLE
                     RTVELIEYCENERKRLNLPDIGYEVGTEETNGGLTSTETYETFITRLKVELDNRGLPM
                     PTFIVGQTGTLTRKTEQVGTFNFRNAYDLAQMAKKYGVGLKEHNGDYLDDVTLLEHIP
                     SQIIATNVAPQYGTEETRAYLKLAEVECKLEKEGLVEKTSNIRHVLLVNAIECGRWRK
                     WVVGEQKNLTTEEIFKDEVLSNEILDIAGHYTFNNDDVKKEIEVLYDNLSKNNIDGQR
                     FVVDHIKRPLRDYAECYNLKGVTTRILNK"
     gene            17435..18151
                     /locus_tag="ACGI5H_002961"
     CDS             17435..18151
                     /locus_tag="ACGI5H_002961"
                     /EC_number="3.1.3.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009901731.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family hydrolase"
                     /protein_id="HFG9698657.1"
                     /translation="MINLIFDVDDTLYNQLTPFYTAYNKVFSSIKDISIEDLYMSSRK
                     YSDEVFHMTENGEMPIKEMHIYRIMKAFEELGNSITEKDAQSFQDEYIYQQSQITLIP
                     EVERILNFSKERNINLGIITNGPSNHQRMKLKQLNIENWVDKSNIFISSEVGFSKPDT
                     NIFRVAENVMNLDRENTYYVGDSYRNDVLGAKKAGWKSIWLNHRGHELEELFYKPDFV
                     ILEHKDLISLFIKICSYKNM"
     gene            complement(18346..18639)
                     /locus_tag="ACGI5H_002962"
     CDS             complement(18346..18639)
                     /locus_tag="ACGI5H_002962"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420959.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="spore coat protein"
                     /protein_id="HFG9698658.1"
                     /translation="MRNMIENLIKNNTYIDDKVIMLSMLSSAKASANMYLNSALTSST
                     PELRAIYSASLTQMVEGHTALTELSINKGWVKPYDKPIQQLTCSYKESQNVID"
     gene            complement(18645..18860)
                     /locus_tag="ACGI5H_002963"
     CDS             complement(18645..18860)
                     /locus_tag="ACGI5H_002963"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9698659.1"
                     /translation="MRILSETEKISLAAIIKMESDGLLMQRAINMLISDEDLKRQSES
                     SILATEGRIKAIQQFIVENEILISEEV"
BASE COUNT         7183 a         2239 c         3060 g         6791 t
ORIGIN      
        1 atagtttgct agctcctgcg aaaacttatt taattcagat ttagtcattt ttttagataa
       61 ttcttctcca atatttagat aaactttttt agatttagat tgttcaacat tcattttttt
      121 caaccccttt tttaagttat aattcaatta tattttaaaa atgctaatac ttcaaatata
      181 aatatttttg tttaagtata taaaacatca ataacattac tcaacacacc ttaaaattga
      241 tttaaatagc tcttttttat gaacaaaatt aatgatataa taaaaaatag aagtgtattg
      301 gtagtacact tctatagtta taactaagca ttctcttgct ggggagtgct tttttcattt
      361 ttccaaacaa cattattttt ttcatcaata attattaaat caatctcatt atcttttaaa
      421 atctctgttg cagtacaaat gagattatct aagtcgaaac tacgagttat ctctagttga
      481 ttgttattta caactctttt aagtacataa gtcttaaagc acatttatat tattatcctt
      541 tctcacaaaa atactttaat taatttttta acatagtaat atttaaaagt agataaaact
      601 aaaaagggtt ctctagaaat caatgtctat ctaattatac ttacttacca ataccatcac
      661 ttggtgtaaa caagactcac tacattttct ccgtactcta atataaaatc atctaactgt
      721 gtatctaaaa aattataata atcatacgaa ctgctaatat aagcagtcaa tacatgtgta
      781 catttatcca ttttattttt aaacatataa attattatac ccctaaaaaa ctttcataaa
      841 aacaaaagaa caatatctct ttggcaactg gctgacataa ctcataagat atttatataa
      901 gtcttagtcc ctatagcttt gcgtcactaa atttctctag ttttgccgat ttagttttat
      961 tctacaacta aaataataca atagaattag ttattattca acaaaattat ttgaaaattt
     1021 aataatttta tagatatgaa agttattttc ttctaagaaa acagactaaa tgcgtagaat
     1081 atttggtaaa acttacctgt ataaattgaa atcagaaggt tttattattg atttagatta
     1141 gaacaatttg agggagtgac ataaaatgaa acaacaagaa gtagttaata aactacgcag
     1201 gggagaattg atgttgatgg aatacttgtg gaggaaaaat tctattttat ctaaaaaaga
     1261 aataatagaa gcaatgaaag aaaaatataa gtggaggaaa agtactacag aaattctatt
     1321 aaaaagatta gtaaaaatga aaacattaaa aaagaagagg ataggttttc agtttagtta
     1381 tgaagtgcta gtaactaaaa aagaatattt aaatgcaata aaagaagata gaaaggtaac
     1441 taaatatgat agttttttta tacgaatgtt taccactatg cataaaaaag aaaagatgac
     1501 agaagaacaa ataaaaaaat atatagaaaa tatggaaaaa attggaaaag aataatttat
     1561 atatatatta attattttta aaataaattt gttataatat ttaaatatac ataaacatac
     1621 ataaatttac aaaaaggggg tgtagcttat gggattcaag aaattgccag attctgagtt
     1681 aaaagtaatg aagtttattt ggggattaga tggaaataag gtagcatcag gagaagttgt
     1741 ggaagcaatg aaacaaattt atgactggaa taaaaatacg acattaacaa tattgtctaa
     1801 gcttgcaaag aaaaactatt tgtattctca aaaaacaagc aagtgtacat attatactat
     1861 cgctgtaaga gaaaaagatt atttaaaagt tgaaacaaaa aaattcttta gtttttttca
     1921 taataattct ttaaaaagtt ttttcactgc tttaaatgat gaagaaaatt taagtgatga
     1981 taaattagat atgttagagg aatgggtgaa aaattgggaa gaagatgaat aaaatgaatg
     2041 tgatactaaa atgatactaa tatgttttat agcgtgttaa aaaatataga aaatatagaa
     2101 ataatagaag aaaattaatg taatagataa ggttttatca gattaaaaag aaaatcaata
     2161 gaatgggaat aaaatataga atgccaaaaa tccacataaa tacaggattt aaggtctctc
     2221 ttacttctat gttatactgg tttgatacta tcaatatttg ccagtatctt atggattaat
     2281 aagtaaaaaa catcctgctg aatgataaat tcagcggggt gtttttattt tgttttagaa
     2341 ctcctttgct ctgaaactcg aagtatttaa cactgatgat tttgttatct tttagttcct
     2401 tttgtgtcat gctctgaaag acaaattgat acaataaaaa agtaatttct taatcattga
     2461 tggagatatg tatttatgtt actcttgatg gtaatttgag taatattgtt catagctttt
     2521 tatattcaat taattagaaa accatttggt ataatcataa ataaacttga tgatataata
     2581 gaaaagattt ataattatta gaagtatata aaagtatttt atgtctatga aatgtatgtc
     2641 tataaaacat atagatgact tttgtatatt aatgtatgaa tattgatatt atagaagaat
     2701 tgagttgtca atgatactaa atcaaatatt tatagaagct ggagggatta tgagaaataa
     2761 aataattata ggaattactt ttttacttgt attactaatg tctggatgtg cttcaaaaca
     2821 aaccgcagaa ataaacgtat tagcaactac tgatttacat ggagttatac cttatgagtt
     2881 aacttcttat gtaaaagaag aaagaaaaaa agataaaaat ctaactttag tagatgcagg
     2941 agattttttt gatagtggag aagtgtttgg ttctagcatg gatagttatt ttagtgctag
     3001 atataaagat ggtgataata acactgaaag ttatattgag acgcctattt caaaagatat
     3061 gaaagaggta ggttatgatg ttgcagttct tgggaatcat gaatttatat ccaacaataa
     3121 attttatcta gataatatga tatctgattt tgagaagcaa aaaataaata ttttatcggc
     3181 aaatacgtat aaaaaaaatg gagacagtta tacaaaacca tacataataa aaaatattaa
     3241 tacacctgaa ggaaacgtaa aactaggaat tttagggctt actataaaag aagttggtga
     3301 gaggaaacag tggaaagatg gaaaacttgt tgactctaag tctttagaac taaaagacca
     3361 agagggctac aatggtgaat tgtatatgaa tgatttagta gaagatgcta aaaagtgggt
     3421 tagtataatg gaaaaagaga agcctgacat tatagttgct gtggcacata caggtgagaa
     3481 acctaagaaa cctaaaaacc caggaaatag aatacaagac ttagctcaac aagttgatgg
     3541 aattgatgct atagttgcag gtcataatca tgttcaaatt gagcaacatg attataaaaa
     3601 taaatcagga gaaaatgtta tagttactga gccaggaaag catggggaat gtatttctaa
     3661 gattaatttt aaattagaaa aaaacaatga taaatggaat atagttgaca aatctagtaa
     3721 attaattaaa tttgaaaaaa atcaagaaag tgataaattt ggagaattta tttcttcaat
     3781 taataaagta agtaaagata agaaagaaat aagattatca gaagtaaaga ctcctgaatg
     3841 ggataaaata tatgttttta aatctggaac atctgcagat gatatatata aaacaatagg
     3901 atataaatgg agaaatatat catctccaaa gagtgatggc atggtgcaga ttgttgtaat
     3961 gaataataat aagcctgtta gctatatata tggtgaagct gaagttatgc caattaatat
     4021 aaaatgtgat gaatcagagt ataaagataa tgttgtaact atttatccta ataaaaatga
     4081 taaatttaaa attgaaaaag gtaaacaaga atatagtatt aatttaaaac atatacaata
     4141 gaaactttta tcttatttaa gtttagattg tacttaaaat aaagtgtgta ttattttaaa
     4201 aattgatgat aattaaaatc acaacattaa ggaatagtac acacttttta tgctaaaaaa
     4261 tagaatgtta aaaaattaaa cctttaaatt aaagtacatt gcttatatta tccaatatta
     4321 tcttcaaagg ttgtgtaata tttttatcct tatgtaatat tgctaacatt ttattttcca
     4381 tatctatccc atctaattca atcaatcgca attttttatg taagagtgaa tctaataata
     4441 aattttctgg caaaatggtt atacctaacc ctgcttgtgc agctttaata agtgcaaaag
     4501 aattaacact ttcccaaaca ggataagctt tttggtttga aagagataat acactgtcca
     4561 aagtatcgcg aatggcactt ccttgctcac gtaacaataa cggaaacgtg cataactgtc
     4621 gtagagataa ggcttgttta gtattggtgg tggttatgca atcatacctt taatccaaga
     4681 gaaagtagta aatcaaactg gatggataag tgagaaaata tttacagata ttataactat
     4741 ttcacaaatg acaccagggc cactggctgt taatacttct acttttgttg gacttcaaat
     4801 tggagggttt tggggagcag ttgcagccac tttaggttgt gtattatgtg gtgtagtaat
     4861 atctctattt ttatataatt tttttcaaaa gcatcagaac tctacttata tatttgaaat
     4921 attaaatggt ctaaaatcag cttcattagg tttaattatc tcagctgcgg ctacaattat
     4981 aattcttgca ttatttggga cgaataaagt gtacttcaat tctatatttg agatgctaaa
     5041 ctggactgca ctaataatct tttttgttac actactgata gtacgtaagt ggaaaattaa
     5101 tcctattgtg attataataa tgagtggtat actgggaata tttttttatt tataagtttt
     5161 tgctaagtaa aggatatcta tttttttata tcttaaatcc aaatagccaa taaagtaagg
     5221 ctatttggat ttttaataaa ttctgaaaag ataatcagaa acctatataa catttaaatt
     5281 atatcactgg ttttctacaa accaatcata agcttcttgg caaaatttct tactatctat
     5341 atagtaacta ttatgaacat tattaatttc aacaagtttc tttttacatt ttagtgaatt
     5401 ataatagcta tcaaaatatt gggttttaaa atatctatca tgaagtgttt taaagacaag
     5461 agtaggtatg ttgactccat cttttatctt actatctttt gcaataaagc attctaacat
     5521 tgtattaatt atctttgtac tatttttcca aatatgagga tttttctttt caaatatttt
     5581 ataaaattca ttatcataga cttcattata acctttatat ttaggtggtt ttactgttat
     5641 gtgaaaatta ggaagaaact taaagaaaaa atataataat ttttatgttc tgttttatat
     5701 attattcata ttttatcaca gataatatac taaagttaat ttttttattg tacaactatt
     5761 ataataattc ttctataata taagacattc tataatttta tatttaagtt catgtgtatt
     5821 taattgtttt tatataaaat gtccagtaat actatttgga tttattttta tttcatcagg
     5881 agttccagaa gcaacaattt cccctccatt tattccactg tctggaccta tatcgataat
     5941 ccaatcagaa gcacgtataa cctctgtatt gtgttcaata attaaaagtg aatgctgttc
     6001 atttacaagt tttctaaaag taattaacaa attttctata tctttaaaat gaagtccagt
     6061 agtaggctca tccaatatgt acagcattcg ttttttagtt tttgtcccta attcttttgc
     6121 taattttatc ctttgagatt ctcctccact taatcctaat gtattttgtc caagctttag
     6181 atatccaagt cccacttcat ctaataagga gagttttcta tatatatcag agcaatcgct
     6241 aaaaaatgtt tttgcttctg ctacttccat gtcaagtata tctgcaattg tctttccctt
     6301 gtattgtata gacagtattt ctttttgata tctcttacct tgacattcac tacaagttac
     6361 ccattggtct gccatatatt gcagaataat ttttgtttta cctaatcctt gacagtttgg
     6421 gcattgcccc tttttgctat taaagctaaa atagctttca tccaataatt tttgttttgc
     6481 ttgtggagtt tcagcaaata gagaacgaat ttcatcaaaa atattgatat atgtagcagg
     6541 tgtagaacgg ctagattttc caataggtgc ttggtccatt aagataaaat catcaatagc
     6601 atcaaatcca gtaaattcag tataattttt atctgggata gatttttgtt tcaatttttc
     6661 ttctagagca ggaagtaaac tgtgaaatac aagagagctc ttaccagaac cactaacacc
     6721 tgtaatagag cacatacagt ttaagggaat ttctacatca atatttttta agttatttgc
     6781 atggcatcct tttaagctta accatttact tggtataatt ttattttgtg aacttatttt
     6841 attgtatgta cttaaatatt tacctgttat agagtttgga ttttttataa tttcttgggt
     6901 tgtaccttct gcgataatga accccccttt tgtaccagca cttgggccta catcaataat
     6961 ataatcagca gacagtattg tatctttatc gtgttccaca actataacag tattaccctt
     7021 atctcttagc tcttctatca ttttgatgat taaattatgg tctcttgggt gtaaaccaat
     7081 agatggttca tctaaaatgt aggttaagcc tactaattca cttcctagct gacttgataa
     7141 tcgtactctc tgcagttctc ctccagataa agttggagct gttctatctg ttgatatata
     7201 gctaagacct acctttaata gataactaac tcgaattttt aattctgtta agatatcatt
     7261 taccaaagag agctcatttt tttgaaggtg atttggtaat tcacacaacc aattccataa
     7321 ctgttctatc gtcatttttg ttagttcagg gaagcgataa cctttgattg tagtgaatct
     7381 agcctcaatg cacagcaatt cgccaccaca tgtattgcaa ggaattttgt tcatatattg
     7441 atgcaaggta ttattttcag aactagattc tctaaaaagt ctttgaatgt ggttgattgc
     7501 tcctgaagca ggtcttctaa tctttgattc tcgtcccttt gattcaaagc taaattcata
     7561 tatcttatcg tctgtaccat ataagattgc atctataaaa tctcttggta attcattcca
     7621 aggtatatct aggtctatat ttttatcttt tgctattgca tataattcac ctaccatcca
     7681 attaccattt ggctttttcc ccctcaattt tccaaaatag taagtagctc catctaatat
     7741 tgaaatagtt gggtctttta caattaattg aggattaact tgataggtaa aacctaatcc
     7801 attacaatcg tgacaagctc cagtatggga gttagcattg aaggttgaag tatttatctt
     7861 agaaaaaata gtttgacaat gtggacaata attttttgta ttattctttt tttctaatgg
     7921 aattttgcaa tatggacagt aactttttcc gattgataca aataacattc ttaaataatc
     7981 ccaaatgctt gtaagagtac caacagtaga gcgaggattt tggcttcctt ttttctgttc
     8041 gatggctata gtaggggtta atccctgaag taaatcaaat tccggttttt gaagctgttc
     8101 tgaaagtttt gctccgttac ttagattttc aaaataacgt ctttttcctt cttcataaat
     8161 cgtatcgaaa gctaaagaag attttccact accacttaca cctgtaataa cagttatttg
     8221 attttttgga attgtaactt caacatcctt taaattgttt tgccttcctc cttttaaata
     8281 gatagagctt ttattatgac aaagtgaatt tttaattgat ttatttattg cttttgtaaa
     8341 tttgaatttc ttttctagtt caagaggatt gcctaattct tttatttccg aaatacctaa
     8401 tatttttaac tgagaaaaga ttgatttcaa ataatcttca ggcaattttt ctattaacaa
     8461 attaagggct tctattttta tatttccgct tgataatatc tctgccattt catctaataa
     8521 atttttttct gctcttgtta attgattgta ttttttggaa cttaattctg tccataaatc
     8581 ccatggaagc aattctaaac caatcatatt attaaagtca tgtagaagat taccctttac
     8641 agaatgccaa cctttccaat ttttattata tccaaagtca tctggatgag catgtccttg
     8701 ccgacatctt atccaggctt ctgaaccagt taaaaaacca tctgtttttc cgacatcatg
     8761 agtgtcaaaa ttaatttgaa aataattttt ttgtatgtca tctatttgtg catctattct
     8821 tatccatctc tttgttagag tatcatagta ttctacaagc cagtggtctt cataagtaag
     8881 ctcactttca aaataattag caaaacctgc tctcattcta gcctcaaaac ctcgatatct
     8941 taggagcgat acaagaagta aagaataatc tctgcacatt ccaacaagcc tttgttttgg
     9001 gtttcttgga atagttagtg ggttagaatt tatttcaaat attcttttta acatttgagg
     9061 aattgtacga agcaattcct catcagattg ttgcttatta aaggatatac catataattt
     9121 tccttggtct ccatgaatta ctaggctttg aaccactttt aataactcaa ttggagtctt
     9181 tggtaaatct tgatatttat tttcaaattt tttaggattt gtgatgatac tttgattttt
     9241 atagttattt attttcattt atatttcacc tctctaaatg gatgatatac cctgacatgg
     9301 tgtcatatgc aaggacaatt tagatttttg gccaaaattt aaaaaataaa taaaaaatga
     9361 tacagtgata aattgtaata caaatatagt ttcaaattgc atataatata attatttaat
     9421 aaaaccatta tctattgaat gttaatgaaa tgttaagatg gcattcttga atattaagaa
     9481 atagaatact ataatatagt gtgaaggatt tttagtaaaa aaatttgtaa gtgttaatat
     9541 acattaaaaa ataggtttat aatttggagg aaaaaaatga aattatcaag gtataagaaa
     9601 aatagtttag ttctgtctat aattttatgt tcacttatta tttcaatcct tgtaattact
     9661 gtttttaata ccgtaaaact acacaatata tctaataaac aatctaaaaa ctatttaaat
     9721 gatgtatcta cacagattgt aatgaatgtt gattctaaaa tcaaatttat tttatccgac
     9781 ttaagaataa tggcagattt tattaagcaa tatgaaggtg atagtcgata tgagtattta
     9841 tctaaaagaa agactagtta taagtattat gatgttggaa taatagattt agaaggtaaa
     9901 gctgagtttt taagtggaaa aaagtttgac ttaaagaata ctgtttccta taaaaaagga
     9961 attgaaggta aagaatactc agaagtaata gagtcaatgg gttttgttct ttatagtgta
    10021 cctatattta atgataatca tgaagtatct agtattttaa taggtgtatc caataaagaa
    10081 agtatgaatg agattcttaa tatagataac tttaatggaa aaggaactat tgaaattatt
    10141 aatagtaagg gaaaacctct tttcatagga aaaaatactg aattaataaa ggaccttagc
    10201 cataaatata agagttctgg agatgaacct tgggcacaaa agatgcttga ggattttaaa
    10261 aatgataaat cagggaatat tacaataacc tcatcaaaag gtgtacaatg cttattaact
    10321 tatcatccaa ttacaagagg tttaaatgat tggcattttc ttctcatagt acctgaagat
    10381 gctgtacttg gtgaacttaa taaattaaac tcttttacaa taacaatgac atttataatt
    10441 acatgtatta ttggaattat aacattaatt ttatatatta taagaagaaa atatgtaaat
    10501 caaatagaaa atattgcata tttagatagt ataacaaatg gtataaattc aactaagttt
    10561 agtatgctag tcaaaccttt aatttcagaa tcacctgata gtacttatat gatgatagca
    10621 atgaatataa aagattttaa gctaataaat gattgtttcg gtagtgaaaa gggaaatatg
    10681 acactaaaac atctttacaa tattttgtat aaaaacattg atgaaaatga agaatttgtg
    10741 tgccgtcatg atgcagacct tttctatttg cttattaaga atagaccagt gttagaagcc
    10801 ctggagttat tatataaaat agaagctgac acaaattatt ttaataaaaa tagggaaaat
    10861 ccatactttt taagactatc agtaggtatt tacacaattg aaaatcataa tgaagattta
    10921 attacaatac aagaccatgc aaatacagca agaaaaagct ttaataaaac tcatcaaagt
    10981 gatttttctt tttatagtga tatagaaaga aaacgattaa tatctgaaaa ggaaatttca
    11041 aatttaatgg aaaaagccct tgaaaataaa gaatttttta tgtgcttaca acctaaaatt
    11101 gatataaaaa gtggaaaaat tagtggagca gagtctcttg tgcgttggaa aaattcagaa
    11161 aagggcataa tttatccaag tgattttatt cctcttttcg aaaaaagtgg atttatatgt
    11221 aagttagatt tatatatact agaagaaaca tgcaaattga tttctaagtg gataaaagaa
    11281 ggtaaagaag tgttgagaat ttctgttaat gtatcacgtc aacatctgaa tgataaattg
    11341 tttttagaaa aatataagca tatatgcaat aaatacaatg taccaacatg tctgatagat
    11401 ttagaactta ccgaatctat tttcttagaa aatccagaag ctatagatat aatagaggat
    11461 attcattcta atggatttaa atgttctata gacgattttg gatttgggta ctcatcatta
    11521 ggaatattaa aggattttaa agttgacata attaagttag accgttcatt ctttgttagc
    11581 aaaaataata tagaccgtgg taaggtagtt attaagtcta ttattgaact tagcaaaagg
    11641 ctaggtatga aagtaactgc tgaaggaatt gaagaattag aacaagttga gtttctaaaa
    11701 aatgtgggat gtgattatat tcaaggttat gttttttcaa aaccattatt aatttctgat
    11761 tttgaaaatt ttgcatatga aaataataaa attaaaaata tccattatta aatgtacaag
    11821 ataaaaaatt taggcaagtt atataattaa aaatataact tgtctttttt atttatatat
    11881 ttaataaaaa tatatttgca gattttgtaa aaataatttt caaatgttgt aagttgtggc
    11941 taaagcttta ttgtattatt ctgaatatag aaagatagtt actgtcttag ataaaaactg
    12001 aaacatacat aataatataa aatttgctat attaataact ctaattattt tggaaggagg
    12061 gaaaatatga taagtgggag aatgttactc atcatgaatt ttctaaaagg aaaaaataag
    12121 acaagttaca aggatattag caaacaactt agtatagaag aaagaaaagt tagatatgat
    12181 ataaataatt taaatattgt tttgcgttca ttaaacaagt cagtaataca aaagatgaac
    12241 aaaggtgtgt taattattcc tgatgacttc caagtagtat gtataaataa taacgaatat
    12301 gtattttcct taactgagcg agtatctatt atgaaaatta tatcaatgtt taaaatagat
    12361 aatctaaact tagaaaaatt aagtaaagaa tttcaggttt ctagaagttc aattaaaaat
    12421 gaccttaatg ttttgtcaag tgaattagaa agaaaccaaa taactattac ttatgataaa
    12481 tcttttaaaa taagtggaga agaagacatt atatataagc aaagattgaa catattaaaa
    12541 tcgtattctt atctttttgg taaggaaaaa tctgatttaa gtgtatttga gaagtattta
    12601 gtgaatgtaa ttgaaaaaat attcaaaggg atttatttga ttgatatata taattggtct
    12661 atgaatttat tattgcaaat gggatggact ttaaatgatg aatcttttac atggtatgtg
    12721 tcaaacattt tcctttttac atggtatata cattcagatg aaaaacatcc tttagaatct
    12781 gcttcattaa gtgagccgtg ttttgaaaat aagtttgacc aagaatttga aacaattatt
    12841 caaaaaaagt tgactaagga acaaattttt ctgttaaaga gttttgtatt ttttacaaat
    12901 aaatatgcaa gtttaaacga ggatatggat ttgattagta cagaaattat agttcaagat
    12961 ctaatttaca atatgtcaga aatattagag attagcttta aagaagatat gattctttat
    13021 aaaggattac tcaatcatat tgccccattg atagagagaa tcaaacagaa tatacagatt
    13081 tatgaggaat tacttcatgt aataccagat aaatatcaat atgtacttga agctactaag
    13141 gtttctattc aaaaaaacag agttttaagt caaataaaga atgaaaatga aacaatactt
    13201 ttggcaatac atttcttagg aagtatacat agaaatgaga ggaataacta caaaaatata
    13261 ttgttagttt gtggatttgg atatggtgta attgctatgt taaaggatag tttagtaaat
    13321 gattaccaga taaatatagt agagagtatt ccatcatata agttacaaga ttataaagaa
    13381 tgggaaagta ttgacttcat tataacaaca tcaaagatag taatagactt gcctaaaaca
    13441 attattgaga taaatccatt tttacaagaa gaggattatt tgaagtttga agaaaaaggg
    13501 ataaaaagaa agaacgtctt aactaattat atgtcaataa aaaaaaggtt ggacttttta
    13561 gaagaagatg cccaaaaaag agtattaagt attatatgtc aagaacttgg atacagtgat
    13621 gagagaatat tatttagaca acttaattta agtgatttaa taggaattga taccataagg
    13681 ataattgatg gagatatgaa atgggaagat gctgtaaaaa ttagttcaaa catacttgct
    13741 aattgtgatt ttgtatcagc acaatatgct gagaatatta tagatatttt aaaaaatgtg
    13801 ggtttttatg ctgtaaaaga taacgaattt gctttactac atggcaatga tagttcatta
    13861 gtcaaagtaa gttcgataag tttattaata tgtaaagaag cagttagttt tggagataaa
    13921 aaggttaaaa tcatattttg cctagcaagc agagataaaa aagagcaaat tcctgcaata
    13981 attaatctaa ctaaaatggt ttataagact aattttattg ctatgttaga aagtgcaaag
    14041 acaaaagaag aagcagaagt tttaattcat aaatatgaga aggaggtcac tgtatgaata
    14101 aattagttaa tgtaaaatgt tcatttaaaa tacatgttaa ttcaaaagaa gaagccatta
    14161 tatcgttagt tgatgtagtg tcaaaagaag gatatttaat agataaaaat caatttttaa
    14221 aagatgtttt aaagagagaa gaaacattgt cgacttatat tggacatggt ataggtcttc
    14281 ctcatagtca aagtgtaggt gttaaaaact cttgtattac aataggaaag cttgatactc
    14341 ctattgaatg gacagaagaa ggagaaaaag tggatttaat atttttgata tcagtaacaa
    14401 aagacaatga aaataatctt catttaaaga ttttatcaaa attagcacgt ttattgatgc
    14461 atgaaagttt tagaaatcaa attagatgtt cagatgaaca aactgtttat aatcttataa
    14521 aagaaaaaat agaggaggaa gattaaaatg agaattttaa agtttttgca aaaacatctt
    14581 atgacagcaa catcttatat gattccattt gtggttgcag gaggaatatt atttgcttta
    14641 tcagtaactt taagtggaca agctgctgtt cctgaaacag gctggttggc taaactgaat
    14701 caaattggag ctgctggctt ggctttattc attcctatat taggtggata tatagcattt
    14761 agtatggcag ataaaccagg attagctcca ggtatgatag gtgcatattt agcaaaagaa
    14821 gtaaatgcag gttttatagg tggtatcata gcaggattta tagcaggatt tgttgtttta
    14881 caattaaaga aaattaaatt agctcctaca atgagaactt taggttctat atttatttat
    14941 cctttagttg gtacattgat tacaggtggt ataattgtat ttttaattgg agaacctata
    15001 gcttctttta tgacatggat gacaaactgg ttaaatggaa tgtctggtgt ttctaaaatt
    15061 cctttaggtg gaatcttagg aggaatgata gcctcagata tgggtggccc tataaataag
    15121 gttgctgcta cttttgccca aactcaagtt gacacacttc catatttaat gggtggagtt
    15181 ggcgttgcaa tttgtatacc tccaattggt ttaggattag ctacattatt gtttccaaaa
    15241 aaatttagca aggaagaaag agattcaggt aaagcttcac tattaatggg atgtgttgga
    15301 attacagaag gagctattcc atttgcaaca tcagatccag ttagagtaat accttgtatt
    15361 atggctgggt cgattgtagg aaatattatg gcttttttat taggatgttt aaatcatgca
    15421 ccctggggag gtctgatagt gttacctgta gttgacaata ggttggggta tattgcatca
    15481 gtattaactg gagcagtagt tgttgcggta ttaatgaaat tagtaaaaaa agacgtgaaa
    15541 gaagatgaag aaattgaaga agatttagat gaatcaattg aattaatatt tgaagaatta
    15601 taaatataaa tggaaggaat ttgtataaaa aagtaaatat aaaactataa atttaaagga
    15661 gataagaata tgaaaattgt agcagtaaca tcttgtccta gtggagtagc acatacttac
    15721 atgtcggctg aatcacttga attatcagcc aaaaaatttg gtatagaaat aaaggttgag
    15781 actcaaggaa gctctggaat agataatgaa ttgtcactta aagatattga tgaagcaact
    15841 tgtgtaatat tgactaatga tgttgagatt agaaatatgg aacgttttaa aggaaagaag
    15901 gtagtaagaa tgagtgtatc tgagataatt aagaaatctg atgcattaat taagaaaata
    15961 aaagatactt ttcaataaaa attgatttat tttacatata actcaaagat gtttttaaag
    16021 aaatttttat taaaagcatc tttgaaaata tcttaaaaat agaataaaag gagatatagt
    16081 catgaaaaag ttaccaataa agactgtcgt gcaaagatta ctaaacttac aagaagaggg
    16141 gaaaagtgca actcttttag gaattggtcc tatgtcacca aacttgttac aagcaagttt
    16201 tgaactagca aaagatgatg attttccttt aatgtttatc gcaagtagaa atcaagtaga
    16261 tgcagatgaa ctaggtggcg gttatgtaaa tggttggaat caggaaactt ttacaaaaga
    16321 tattaagaag gttgccgaca aagttggatt tgatggttta tattatttat gtagagacca
    16381 tggtgggcca tggcaaagag ataaagagag aaatgaccat ttgcctgttg atgaagcaat
    16441 ggagttagga aaaaaatctt atttagcgga cattgaagca ggttttgacc tattgatgat
    16501 tgaccctaca aaagacccat ttgaaattgg aaaagtaatt ccactagatg tagtactaga
    16561 aagaactgta gaattaattg agtattgtga aaacgagaga aaaagactta atctaccaga
    16621 cataggttat gaggttggta cagaggaaac caatggaggt ctgacttcaa ctgagacgta
    16681 tgaaacattt ataactagac taaaggttga actcgataat agaggtttgc caatgccaac
    16741 atttatagtt ggtcaaactg gtactttaac tagaaagaca gaacaagtag gaacttttaa
    16801 ttttagaaat gcttatgatt tagctcaaat ggctaagaaa tatggagttg gtttaaaaga
    16861 gcataatggc gattacttag atgatgtaac tttattagaa catataccat ctcaaattat
    16921 tgctacaaat gtagctcctc aatatggtac tgaagaaact agggcatatt taaaattagc
    16981 agaagttgag tgtaaattag aaaaagaggg cttagttgag aaaacttcta atatcagaca
    17041 tgttcttctt gttaatgcaa ttgaatgtgg acgttggaga aaatgggtag taggagaaca
    17101 aaaaaatcta actactgaag agatatttaa ggatgaagtt ttatctaatg aaatactaga
    17161 tattgcagga cattatacat ttaataatga tgatgttaaa aaagaaatag aagtgcttta
    17221 tgataattta agtaagaata atattgatgg tcaaagattt gttgtagacc atattaaacg
    17281 tcctttgcgt gattatgcag aatgctataa cttaaaaggt gttactacga ggattttaaa
    17341 taaataatag gacttatagt ggtgagtatt gttatactag gtatttatag ttataattat
    17401 acttaccact attaaattta ggaggactaa tattttgatt aatttaattt ttgatgtaga
    17461 tgatacttta tataatcaat taacgccttt ttacactgca tataataaag tgttttcttc
    17521 aataaaggat atttctattg aagatttata tatgagtagt agaaagtata gtgatgaggt
    17581 atttcatatg actgaaaatg gagaaatgcc aatcaaagaa atgcatattt ataggataat
    17641 gaaagctttt gaggagttgg gaaattctat tacagaaaaa gatgcacaaa gttttcaaga
    17701 tgagtatata tatcaacaat cacaaattac actaatacca gaagttgaga ggattttaaa
    17761 tttttctaaa gaaagaaata ttaatctagg aattataact aatggcccat caaaccatca
    17821 aagaatgaag ttaaagcagt taaatattga aaactgggtt gataaaagta atatttttat
    17881 ttctagtgag gttggatttt ctaagccaga tactaatatt tttagagtag ctgagaatgt
    17941 tatgaattta gatagagaaa atacatatta tgtgggtgat tcttatagaa atgatgtatt
    18001 aggtgctaaa aaagctggtt ggaagagtat atggttgaac cataggggac atgagttaga
    18061 agagttgttt tataaacctg attttgtaat tttggaacat aaggatttga tatctttatt
    18121 tataaaaata tgtagttata aaaatatgta gtaaaaaaat gttaataata gaattgtata
    18181 aaataattaa taataactat ataaaattat atgtttagat tgtgagcaat ctattttatg
    18241 ttaaaaatag attatttaga agaaggggaa atcttaaaaa aatttgaata tccccttttt
    18301 attatttaat taaaatgaaa tagttagaaa tatattttat ttagtttagt caataacatt
    18361 ttgggattct ttataactac atgttaactg ttgaataggt ttatcatatg gtttaaccca
    18421 tcctttatta atacttaatt ctgtaagtgc tgtgtgacct tctaccattt gagttaatga
    18481 agctgaatat atagctctta gttcaggtgt actacttgtc aatgcagaat taagatacat
    18541 attggcagat gctttagcag atgaaagcat acttaacatt attactttat cgtctatata
    18601 agtattgttc ttaattagat tttctatcat atttctcatg ttatctatac ctcctcagaa
    18661 attagtattt cattttcaac tataaattgt tgtatagctt taattcttcc ttctgttgct
    18721 aatatactag attctgattg tctttttaga tcttcatctg atattaacat atttattgct
    18781 ctttgcataa gtaatccgtc agactccatt tttataattg ctgctaaaga tattttttca
    18841 gtttctgaaa gtattctcat ttaatcatct cctatattgt aatttatgct ttaatagtat
    18901 gtctttcttt tcaaggaaat aaccattaca cttttttaca gtattttata ttctcgttat
    18961 atcaaaattt agtcgactta atatattaat ataattttgt aggatattta tcattaaata
    19021 tctataaaat aaattgtttg aatattcata aagcaaaatt tatttgtatg tacttcttca
    19081 agagtaaata tgagtttttt caaaaaatta atttttatga taattattaa gggctatatt
    19141 tttcttaaag ttgtgattat cattattaat ttacaataaa attgccgaaa agccctctcc
    19201 tttaggtgta gggatgaaag gtaaggtctt aatataaaaa agttagaata atgcttgtaa
    19261 tctaataccg cta
//
LOCUS       DAYAOO010000078        18822 bp    DNA     linear   BCT 12-OCT-2024
DEFINITION  TPA_asm: Clostridioides difficile isolate ST8-SSI-h139-18
            SAMN40601845-rid21577343.denovo.078, whole genome shotgun sequence.
ACCESSION   DAYAOO010000078 DAYAOO010000000
VERSION     DAYAOO010000078.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN40601845
            Sequence Read Archive: SRR28438827
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 18822)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 18822)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-MAY-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-MAY-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002157583.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002157583.1
            Genome Coverage       :: 163x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/11/2024 16:19:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 4,038
            CDSs (total)                      :: 3,963
            Genes (coding)                    :: 3,930
            CDSs (with protein)               :: 3,930
            Genes (RNA)                       :: 75
            rRNAs                             :: 6, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 60
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 33
            CDSs (without protein)            :: 33
            Pseudo Genes (ambiguous residues) :: 0 of 33
            Pseudo Genes (frameshifted)       :: 7 of 33
            Pseudo Genes (incomplete)         :: 25 of 33
            Pseudo Genes (internal stop)      :: 11 of 33
            Pseudo Genes (multiple problems)  :: 8 of 33
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..18822
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN40601845-rid21577343.denovo.078"
                     /isolate="ST8-SSI-h139-18"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Denmark"
                     /collection_date="2018"
                     /collected_by="Statens Serum Institute"
     gene            complement(285..677)
                     /locus_tag="ACGI5H_002964"
     CDS             complement(285..677)
                     /locus_tag="ACGI5H_002964"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433356.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_function: GO:0016987 - sigma factor activity [Evidence
                     IEA];
                     GO_process: GO:0006352 - DNA-templated transcription
                     initiation [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-70 family RNA polymerase sigma factor"
                     /protein_id="HFG9698660.1"
                     /translation="MAALKSFEKPLTPEEEIEYLTKFKIENDKSAKDTLIERNMRLVA
                     YIAKKYNNSTEDQDDLISIGTIGLIKAIETYNIDKGTRLATYASRCIENEILMNIRSN
                     KKNKTQVSLQDPIGTDKEGNEINTTLYM"
     gene            1244..1606
                     /locus_tag="ACGI5H_002965"
     CDS             1244..1606
                     /locus_tag="ACGI5H_002965"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905375.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9698661.1"
                     /translation="MKIRKSGFISIECIISIAILYVAVYLVSTSLYNCYSFISRNISD
                     REMLSTAKKYIEDEKYRIQNSKYELIEDKIEKNYINGYEINSKIEQILDYYQCYEINI
                     EIKNEFKKLRFNSYVTRK"
     gene            1590..2315
                     /locus_tag="ACGI5H_002966"
     CDS             1590..2315
                     /locus_tag="ACGI5H_002966"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018112787.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9698662.1"
                     /translation="MLLENKGSILIITLIIFSIISTVCIMCIGLIYTHNNMFELGYKD
                     IQLKEISLSGIEISVSNVLSCVEEAIDVSNNEDEFREYFLGNNMIECIKKIKDTSYSS
                     LEELSLKVENNTIYDRGDFFEFDIESNVREKEFLKAIKVRVKIKNPWIGIDIEDYMDK
                     SNNNKIDDKTFNNYKASENNEILNQFKNESENIRNQEVGGFTEEDEEDEEYEEELKQN
                     IIENIKKNFDEKNLVQVYKYRGV"
     gene            2335..2754
                     /locus_tag="ACGI5H_002967"
     CDS             2335..2754
                     /locus_tag="ACGI5H_002967"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902379.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9698663.1"
                     /translation="MTVIELIVSISIILLIVTLSFPKDNLENHKINLFARQLCSDIRY
                     VRRINMFSNYNTYIYYINQGKHEGYVLRKDGKNIKSIMLPKNAKIARSIEIIKFKSDG
                     SPQKASTIEIYNNRLRKTITITPVSGRVLLKEGKYET"
     gene            2744..3268
                     /locus_tag="ACGI5H_002968"
     CDS             2744..3268
                     /locus_tag="ACGI5H_002968"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438204.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9698664.1"
                     /translation="MKHKYGYLLLESVVSLSSMVIIILVLYSIFLSTINLKLKVEDKI
                     ELQQQSLEIIKSMEGIISNSMGIMNVSNYEETFKKTTSIKCRYLDENNNEEGISNKEI
                     ILNERRNKLFVNSLNGESSQAGGYEIGDYVDEMYVSITNNGQYVNIKLKLSKRSQKYE
                     TDFKIKVWNFSESI"
     gene            3580..4137
                     /gene="efp"
                     /locus_tag="ACGI5H_002969"
     CDS             3580..4137
                     /gene="efp"
                     /locus_tag="ACGI5H_002969"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889023.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0003746 - translation elongation factor
                     activity [Evidence IEA];
                     GO_process: GO:0006414 - translational elongation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor P"
                     /protein_id="HFG9698665.1"
                     /translation="MVSAGDFRKGVTFEKDGQPCLVVDFQHVKPGKGAAFVRTKYKNL
                     KTGAIREESFNPSEKFPKAVIDTRQMQYLYNDGELYYFMDQENFEQIPLNYEQVEDAI
                     KFLKENEVATIRFYQGQPFQVEAPNFAELEVTDTEPGIKGDTASNVTKAATVETGAVV
                     QVPLFINTGDKVKIDTRTGEYLSRV"
     gene            4229..4684
                     /locus_tag="ACGI5H_002970"
     CDS             4229..4684
                     /locus_tag="ACGI5H_002970"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419314.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CD1247 N-terminal domain-containing protein"
                     /protein_id="HFG9698666.1"
                     /translation="MKHLYEEVAYLKGLAEGLEISAESKEGKMIHKIVDALEVFADAI
                     VTLDEEQEELQDFVESIDEDLADLEEDIADMEEDLYEEDDDEDDEDFSYIEMECPNCG
                     ELVEIDEDLLYDDEVDVVCPDCKAVILSSEDDCDDDCTCGGCSSCDDRE"
     gene            4847..5557
                     /gene="rnc"
                     /locus_tag="ACGI5H_002971"
     CDS             4847..5557
                     /gene="rnc"
                     /locus_tag="ACGI5H_002971"
                     /EC_number="3.1.26.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428341.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0004525 - ribonuclease III activity
                     [Evidence IEA];
                     GO_process: GO:0006364 - rRNA processing [Evidence IEA];
                     GO_process: GO:0006396 - RNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease III"
                     /protein_id="HFG9698667.1"
                     /translation="MKISKKLLDNIQRFENVINYKFKNKEYILEALTHSSYSNENKKY
                     NFNERLEFLGDSVLGIVISDYLFNEEANLPEGELTKLRANIVCEDSLSEVANDINLGI
                     HMLLGRGEEATGGRHRTSILADAFEAVIAAIYLDGGFESARQFILHHMENIIYDSRKG
                     NIFRDYKTHLQEVLQGNGENNIWYRLIEEKGPDHNKRFVMEVGINDDVLGIGEGKSKK
                     EAEQLAAKIALKKKLWEK"
     gene            5611..6681
                     /locus_tag="ACGI5H_002972"
     CDS             5611..6681
                     /locus_tag="ACGI5H_002972"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438208.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016407 - acetyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0006448 - regulation of translational
                     elongation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="elongator complex protein 3"
                     /protein_id="HFG9698668.1"
                     /translation="MKKRIIPIFVPHKGCPHDCIFCNQKKITGVSTDVTSEDARNIIE
                     ECLETIDKDADVEIAFFGGSFTAIDIDIQKSLLSVAKEYVEKGLVKDIRMSTRPDCID
                     EDILSMLKEYKTSIIELGVQSLDEKVLLDSIRGHQSEIVYKSSKMIKNSGIKLGLQMM
                     IGLPADTEEKCIFTAKKFVELKPDCVRVYPTLVVKDTGLEKLMEQNKYNPFTLEESVN
                     IVKKVLVLFYVNNINVIRVGLQATDDIQIGKAVLAGPYHPAFRELVEADMIKDYLEFV
                     ILQNKNIKQMLVKSNKKNISKIIGNKKTNVKYMEEKFGVLLKTQESDLDINQLEIVLD
                     GKSLISANMRDIHRKLYDIYDL"
     gene            6709..10263
                     /gene="smc"
                     /locus_tag="ACGI5H_002973"
     CDS             6709..10263
                     /gene="smc"
                     /locus_tag="ACGI5H_002973"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896160.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0007059 - chromosome segregation [Evidence
                     IEA];
                     GO_process: GO:0030261 - chromosome condensation [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="chromosome segregation protein SMC"
                     /protein_id="HFG9698669.1"
                     /translation="MYLKRLELKGFKSFPVKTDIIFKEGITAIVGPNGSGKSNISDAV
                     RWVLGEQSIKSLRGDKLEDVIFAGTDTKKPMNYCEVALTIDNSENQLELDFTEVTIRR
                     RAYRNGESEFFLNNKSCRLKDIKEVFLDTGIGKDGYSIIEQGKVDEILSNNPLSRRKV
                     FDEACGISKYRYKKQEAERNLSNTKENLERIDDVYIEIENQLKPLFNQQTKAKKYLEI
                     SEKLKTLEVNSFIREIEGIEKELSEVNEHRKVIEKELNEKEEQKNVVEKKQEDINKEV
                     EVLQDVIEKSVDYINSIKGVISKKESQINLIKERIRNFTNEISRKNLEIKDIKEKLNE
                     NKQYIKELESNKLSGSEELSTLQENIKVLEGSKDKQKIKLESLNNEIELLKESIIDIL
                     NKKQEFSNKLSTLNANKENMNIRDENINSEITELNKNIEIKSSELDTINKEFNMQNEN
                     LKNVNNRHKELSINLQDSISEHNKLEDEIQKSKYNLNGYNSKLNVYIDMENHYEGFNR
                     GVKEVLKNKNLKGVHGALGQIINVPEKYEKSIEAALGAYMQNIITDNEFSAKFAINYL
                     KQNNLGRVTFLPLNIIKSNKISLGNLKANTKFIGIASDLITFDEKYRNIIENILGRTI
                     LINNIDEGIKFAKETGHRFKIVTLDGEILNPGGSLTGGSLKTNGNILSRKRYINEYTE
                     KISNIKNEISHLELKRESLDKDVKNIKNEIDSHESKIKDLEKSIIIKSTSIKNVESEI
                     ESLKGSITKLENEKNDLNSNLNYTLEKSDDVRKDMEELDDLYNKNKEKIDALNEEIKR
                     YNDLYDKEKSEFDELNLSLVKKTEVYNSIVRDIKRISGENCELEEKNKQLEESLNYEE
                     HEIIKLQDSILTEEKEKENLTKQLGDSNRNLETRKIAKDDLKNSFDEINKELKTIDRQ
                     HIELKESLFKVGGRLERLKTSQDTYINKLFEQYDMTLVQALEIKDEDLDIDRKFLESL
                     KREIRSLGNINIDSIKEYEEIKERYDFYSEQKQDLEESMEEIEKLIHTLEENMKSEFE
                     IKFEEISKNFKYVYKRLFGGGCGELTILDKENLLESDILITAQPPGKKMKNLNLLSGG
                     EKALTAISILFAILITKPTPFCILDEIEAPLDDANIFRFGEFLKDLSKETQFISVTHR
                     RGTMEAADYIYGVTMQEKAISKVISLKLKEAQEITDII"
     gene            10290..11570
                     /gene="ftsY"
                     /locus_tag="ACGI5H_002974"
     CDS             10290..11570
                     /gene="ftsY"
                     /locus_tag="ACGI5H_002974"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902385.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003924 - GTPase activity [Evidence IEA];
                     GO_function: GO:0005047 - signal recognition particle
                     binding [Evidence IEA];
                     GO_process: GO:0006614 - SRP-dependent cotranslational
                     protein targeting to membrane [Evidence IEA];
                     GO_process: GO:0009306 - protein secretion [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="signal recognition particle-docking protein
                     FtsY"
                     /protein_id="HFG9698670.1"
                     /translation="MLKKLFGFGKDKEKEIEKKDAEEEIEVEDSVDNLENLEETIFSG
                     LEEEVIDKVEDIEEKNEESVNNEGTEEIENFEKIEVEMDSNGKEVENISNNDSQEEII
                     EELENYDEIESKEIEDKEDKKVNLFERLKQGLTKAKQGITDRIDEVLKSYTKIDEELL
                     EDLEEILITADVGVNTTMDIIERLRDKIKQKGITEPIKVREELKSIVEDILTNENSTL
                     DIEPAPCIILMVGVNGVGKTTTIGKLANRYKKDGKKVLLAAADTFRAAATEQLEIWAN
                     RTNVDIIKHQEGADPGAVVFDAIKAAKARKTDVLICDTAGRLHNKANLMNELGKVFKI
                     VDREFPEAKREVLLVVDATTGQNAVVQAKTFKEVADITGIVLTKLDGTAKGGVVLAVK
                     SEVDVPVKLIGVGESVEDLQDFNAKSFSDALFGN"
     gene            11673..12041
                     /gene="ylxM"
                     /locus_tag="ACGI5H_002975"
     CDS             11673..12041
                     /gene="ylxM"
                     /locus_tag="ACGI5H_002975"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419333.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0048500 - signal recognition particle
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="YlxM family DNA-binding protein"
                     /protein_id="HFG9698671.1"
                     /translation="MNIEKMVEIGLLFEQYKELLTDKQKEIVALYYEEDYSLGEISEN
                     LNVSRQGVYDTLKRSEKILRDYEEKLHLVSKIQEQEKNIKIIKDKIIDIKEDLLHNRD
                     CANLIPKLENIEDVCREMIK"
     gene            12038..13390
                     /gene="ffh"
                     /locus_tag="ACGI5H_002976"
     CDS             12038..13390
                     /gene="ffh"
                     /locus_tag="ACGI5H_002976"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419335.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0048501 - signal recognition particle,
                     plasma membrane targeting [Evidence IEA];
                     GO_function: GO:0003924 - GTPase activity [Evidence IEA];
                     GO_function: GO:0005048 - signal sequence binding
                     [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_process: GO:0009306 - protein secretion [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="signal recognition particle protein"
                     /protein_id="HFG9698672.1"
                     /translation="MIFEGLSDKLQGAFSKLKSKGKLTEVDVKNAMREVKLALLEADV
                     NFKVVKDFIKKVQERCVGQEVMQSLTPAQHVIKIVNEELTSLMGDVQSKVMISSKPPT
                     ILMMVGLQGAGKTTTAGKLGGYFKKQGKKPLLVACDIYRPAAIKQLQVVGEKLDIPVF
                     NMGDKENPINIAKAGLSHAIKNANDLVIIDTAGRLHIDEVLMDELKSIKSEVKPHEIL
                     LVVDSMTGQDAVNVAESFNEALGVDGVVLTKLDGDTRGGAALSIRAVTQKPIKFMGMG
                     EKLDDIEPFHPDRMASRILGMGDVLSLIEKAQENIDLEKAKELEQKIKKQELDFEDFL
                     QQMEQIQNMGPLDKILGMIPGMGNVKDQLGDVDLNGKEMKRTKAIIQSMTTYERRNPG
                     VLNASRKKRIAKGSGTSVQDVNRLIKQLNEMKKMMKMFAGSQKSMKKRGGLGGLPFFK
                     "
     gene            13428..13700
                     /gene="rpsP"
                     /locus_tag="ACGI5H_002977"
     CDS             13428..13700
                     /gene="rpsP"
                     /locus_tag="ACGI5H_002977"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419338.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0000314 - organellar small ribosomal
                     subunit [Evidence IEA];
                     GO_component: GO:0022627 - cytosolic small ribosomal
                     subunit [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S16"
                     /protein_id="HFG9698673.1"
                     /translation="MAVKIRLKRMGANKKPFYRIVVADSRAPRDGKFIEEIGYYNPIS
                     EPKQVRINDEKAIKWLATGAQPTEVVKKLLVKNGVIEKFEASKQAK"
     gene            13765..13992
                     /locus_tag="ACGI5H_002978"
     CDS             13765..13992
                     /locus_tag="ACGI5H_002978"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="KH domain-containing protein"
                     /protein_id="HFG9698674.1"
                     /translation="MKELVVDIAKALVDNPDSVVVEEFEDNDGIVLKLTVAQEDMGKV
                     IGKQGRIAKAIRTVVRSVANRENIKVSLEIV"
     gene            14100..14615
                     /gene="rimM"
                     /locus_tag="ACGI5H_002979"
     CDS             14100..14615
                     /gene="rimM"
                     /locus_tag="ACGI5H_002979"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438220.1"
                     /note="Essential for efficient processing of 16S rRNA;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0043022 - ribosome binding [Evidence IEA];
                     GO_process: GO:0006364 - rRNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome maturation factor RimM"
                     /protein_id="HFG9698675.1"
                     /translation="MKEKLTHFKVGQIVNTQGLKGEVRVYPLTDDIERFDELKDFYLG
                     KDLNNKLAVEKVRYKGSMVIMKIKGIDSIEKAEKLKNKFMYVAREDSRELEEGEFFIA
                     DMIGMEVLTVDGKYVGILEDVLQYSANDVYVVKGEEDKEFMIPAIKKFVPTIDIDERK
                     MIIDPIKGMID"
     gene            14624..15319
                     /gene="trmD"
                     /locus_tag="ACGI5H_002980"
     CDS             14624..15319
                     /gene="trmD"
                     /locus_tag="ACGI5H_002980"
                     /EC_number="2.1.1.228"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428328.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0052906 - tRNA
                     (guanine(37)-N1)-methyltransferase activity [Evidence
                     IEA];
                     GO_process: GO:0030488 - tRNA methylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (guanosine(37)-N1)-methyltransferase TrmD"
                     /protein_id="HFG9698676.1"
                     /translation="MRFHIMTLFPEIFNSYMDESIMKRAVEKGIIEVHIYNIRDFSNN
                     KHKKVDDYPFGGGAGMVMTPQPIYDTYKHIITTHNINNPSVIYLTPKGKVYNQSMAKQ
                     MSLKEDIILLCGHYEGIDERIIDLIVTDEISIGDYVLTGGELPALIMIDSISRLIPGV
                     LNQEESFEEESFKDNLLEYPHYTRPRDFEGLKVPEVLLSGNHKKIDEWRREESIRITK
                     ERRFDLYKKSNEK"
     gene            15504..15854
                     /gene="rplS"
                     /locus_tag="ACGI5H_002981"
     CDS             15504..15854
                     /gene="rplS"
                     /locus_tag="ACGI5H_002981"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419350.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0000311 - plastid large ribosomal subunit
                     [Evidence IEA];
                     GO_component: GO:0022625 - cytosolic large ribosomal
                     subunit [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L19"
                     /protein_id="HFG9698677.1"
                     /translation="MNEMLRAIEQEQLKNEVPNFGPGDTVKVHVRIIEGKRERIQVFE
                     GVVLKRQGGGARETFTVRKMSFNVGVERTFPVHSPKIEKIEVTRKGKVRRAKLNYLRG
                     RVGKAAKIKEARNK"
     gene            16175..17071
                     /gene="ylqF"
                     /locus_tag="ACGI5H_002982"
     CDS             16175..17071
                     /gene="ylqF"
                     /locus_tag="ACGI5H_002982"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428326.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0003924 - GTPase activity [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_process: GO:0042254 - ribosome biogenesis [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome biogenesis GTPase YlqF"
                     /protein_id="HFG9698678.1"
                     /translation="MSNEYEEYLMNDNLHINWYPGHMKKTKELVKNNLKLIDVVIELL
                     DARIPFSSKNPDIDRLVGDKPRVVVLNKSDMADRDKLNQWIEYYKKINIKAIPVDTIK
                     GVGINKIIEECKNVTREKMSSLKDKGRKERAIRIMIVGVPNVGKSSLINKLTGRKSTQ
                     TGDKPGVTKGKQWVRLKGNLELLDTPGILWPKFEDQEVALNLAFSRAIKDEILDTETL
                     ALRLIEKLMKIEPEKLKARYKLDCLGETPIETMDMIGHKRGFITGKKELDYTRIATTV
                     LNEFRDGKIGNITLEVPENVKR"
     gene            17460..18752
                     /gene="brnQ"
                     /locus_tag="ACGI5H_002983"
     CDS             17460..18752
                     /gene="brnQ"
                     /locus_tag="ACGI5H_002983"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438230.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0015658 - branched-chain amino acid
                     transmembrane transporter activity [Evidence IEA];
                     GO_process: GO:0015803 - branched-chain amino acid
                     transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="branched-chain amino acid transport system II
                     carrier protein"
                     /protein_id="HFG9698679.1"
                     /translation="MGKTKDVIVFGFALFAMFFGAGNLIFPPYLGIITGPEWLIAFLG
                     FTFADAGLALLAVMATAKFDGNVVEMFKRCGMKLGILIGCADILCIGPFLAIPRTGAT
                     TYEMGIMPLFGTSIPVLLFCILFFAISYVLTIRPSKVVDIVGQFLTPALLIALAFIII
                     KGIISPLGDIVDKPMIPNVFAEGIGQGYQTMDAFAAIALASVLIVSLNDKGYSTISDK
                     LKMIGKAGVLACGGLALVYGGLCFLGATVSTMYGTDAVQSQVIVNITEGLLGNVGKAI
                     LAVVVSLACLTTSIGLTSATGQYFSRLTKGKLSYEKIVLAVSVFSAVVASFGVGTIIK
                     IASPILSIVYPPSIVLIILAFFNEKIKNDNVYKGAVYMSLFVSILTVISSYGVAVPVV
                     NSLPLNSLGFNWVVPVIIAGIIGNFIPSKSQSNTLGTN"
BASE COUNT         7957 a         1749 c         3480 g         5636 t
ORIGIN      
        1 atgacaaaat aaaaaatact atttaaatag atattaaaaa attgatacca agtatttgtt
       61 tgctatatga ataacaattt atttaggagc tttacttgga cactgtataa taataaagta
      121 attgctaaaa acgtttgatg atttggatgt atttttagaa attagaaaaa tatatactta
      181 ctgactaatg ataatcttat atgtatttta gtttgagtga tttaagaaaa gtgttttgaa
      241 agggaattat tttatagagt aaataaatat ataatagtag aaaattacat ataaagagta
      301 gtgtttattt cattaccttc tttatctgtt ccgatagggt cttgtagaga tacttgagtt
      361 ttattttttt tgttagatct aatattcatt aaaatctcat tttcaataca tctagaagca
      421 tatgttgcta atcgagttcc tttatctatg ttataagttt ctatagcttt aattaatcct
      481 attgtaccta tggatattaa atcatcctga tcttccgttg aattattata tttctttgct
      541 atataagcta ctaatctcat gtttctttca attaatgtat cttttgcact tttatcgttt
      601 tctattttaa atttagttaa atactcaatc tcttcttcag gggttaaggg tttttcaaaa
      661 gatttaagag ctgccaatag gtcaccccct tttcaacggt cactttaaat tatatgaagg
      721 agacttatcc aagttgactg ttatctaata aaataatatg catattttta gaatttaaaa
      781 catatatttg caaacttttg aatggaatat gacataaaga gtgggaattt aaatttaagt
      841 ttttgttgta tatatatgaa ataaggcgaa gaaattattg atttataaag tataaattgg
      901 aattgaggtg tcaataaata taaaaggaaa tagtatttat atatgttttg gtgttgaagt
      961 aaaagattaa tgcaaagcat tagagtctat aaaaatatga atataggagg tgtaatttta
     1021 caatacttaa aaaagtaaat gtaattaatt gtttgtataa agttgattac aagcaaaagt
     1081 atcagtcata gttaatactg ttaagggtga aggtggtgtg ttaatttata tatgtatggg
     1141 aagaaatttt gattacaatg aaaaaactta caaaagatat ttatgaaaaa acttatagtt
     1201 aaatgtttat atataaaata ttatttaggg gttgttttta ttattgaaaa taagaaagag
     1261 tggttttata tcaattgaat gtataataag tattgctata ttatatgtgg ctgtttattt
     1321 agtttctaca tcattgtata attgttatag ttttatcagt agaaatatat ctgacagaga
     1381 aatgttaagt acagcaaaaa aatatataga agatgagaag tatagaatac aaaatagtaa
     1441 gtatgagtta attgaagata agatagaaaa aaattacata aatggatatg aaattaacag
     1501 taaaatagag caaattttag attattatca atgctatgaa ataaatatag agataaaaaa
     1561 tgaatttaaa aaactgaggt ttaatagcta tgttactaga aaataaaggc tctatattaa
     1621 taataacatt gataatattt tctattataa gtactgtgtg cattatgtgt ataggtttaa
     1681 tttatacaca taataatatg tttgagttag gatacaagga cattcaacta aaagaaattt
     1741 ctttaagtgg aatagaaata tcagtaagta atgtactttc ttgtgttgag gaagctattg
     1801 atgtatctaa taatgaagac gaatttagag aatatttctt aggaaataat atgattgaat
     1861 gtataaaaaa aataaaagat acatcttata gtagtttaga agaactttct ttaaaagtag
     1921 aaaataatac tatttatgac agaggagatt tttttgaatt tgatatagaa agtaatgtta
     1981 gagaaaaaga atttttaaaa gcaataaaag taagagtgaa aatcaaaaat ccatggatag
     2041 gaattgacat tgaagattat atggataaat ctaataacaa taaaattgat gacaaaacat
     2101 tcaataatta taaagcatct gaaaataatg aaattctaaa tcaatttaaa aatgaaagtg
     2161 aaaatataag gaatcaagag gttggtggat ttacagaaga agatgaagaa gatgaagaat
     2221 atgaagaaga acttaaacaa aacataattg aaaatataaa gaagaatttt gatgaaaaaa
     2281 acctagtaca ggtatataag tataggggtg tataactttg aaaaaagaag gaatgtgact
     2341 gtaatagaat taatagtatc tatcagtata atactcttga tagttacatt atcttttcca
     2401 aaagataatc ttgaaaatca taaaataaat ttatttgcac gtcaactttg ttcagatata
     2461 aggtatgtta ggcgaattaa tatgtttagc aactacaata catatatata ttatataaat
     2521 caaggtaaac acgaaggtta tgtattgaga aaagatggta aaaacattaa atcaataatg
     2581 ctacctaaaa atgcaaaaat agctaggagt attgaaataa taaagtttaa atctgatggg
     2641 tcgcctcaaa aggcgtctac aatagagata tataataata gattaagaaa aactataaca
     2701 ataacacctg taagtggaag agtacttctg aaagagggaa aatatgaaac ataaatatgg
     2761 ttacttgctt ttggaaagtg tcgtatcatt gtcttcaatg gtgataatta tactagtttt
     2821 atattctata tttttgtcta caataaactt aaagttaaaa gtagaagata agatagaact
     2881 acaacaacaa agtcttgaaa tcataaaatc tatggaagga attattagca attctatggg
     2941 aataatgaat gtatctaatt atgaagaaac atttaaaaag acaacatcta taaaatgtag
     3001 atatttagat gaaaataata atgaagaagg cataagtaat aaagaaatta tattgaatga
     3061 aagacgaaat aagttatttg taaattcttt aaatggcgaa agtagtcaag caggtggtta
     3121 tgaaattgga gattatgtag atgagatgta tgtatcaatt actaataatg gtcaatatgt
     3181 taatattaaa ttgaaattat caaaacgtag tcaaaaatat gagactgatt tcaaaataaa
     3241 agtatggaat tttagtgaaa gtatatagaa atacataaat ttaagagaaa gaagtgacat
     3301 caataagtca tataaaatat aattattgag aactatataa ctaaataata tcaatatgta
     3361 aagtgtatag attaagaata tagaggataa taataaaaat atagaataag taatttgcca
     3421 aatacttgtt tatattgtat aacttatgat attatgatat tagtaaaaat ttgtaatcct
     3481 gacttgacag aattcaagta agagatataa ttttaaaggc atagtaatgt aaaatttact
     3541 aaaaaataag aaatttattt taatatggag gaacaaaaaa tggtatcagc aggtgatttt
     3601 agaaaaggtg ttacatttga aaaagatgga caaccatgtt tagtagttga ttttcaacac
     3661 gttaagccag gtaaaggagc tgctttcgtt agaactaaat acaaaaactt aaaaacagga
     3721 gctataagag aagaaagttt caatccaagt gaaaaattcc ctaaagctgt tatagataca
     3781 agacaaatgc aatatctata caatgatggt gagttatatt attttatgga tcaagaaaat
     3841 tttgaacaaa taccattaaa ctatgagcaa gttgaagatg caattaagtt cttaaaagaa
     3901 aatgaagttg ctacaataag attttaccaa ggacaaccat tccaagtgga agcgccaaac
     3961 tttgcagagc tagaagttac agatacagag ccaggtataa aaggtgatac agcaagtaat
     4021 gtaactaaag cagctacagt tgaaactgga gcagttgttc aagttccatt atttataaat
     4081 actggagata aagtaaagat agatactaga acaggtgaat atttatcaag agtataaaaa
     4141 tttatgtata taaaagctta tatgtcttaa taatataaga tatatgagct tttagtttat
     4201 atataaaaaa gaaagcgagg ggtgttacat gaaacattta tatgaagaag ttgcatactt
     4261 aaaaggccta gcagaaggac tagaaataag tgctgaaagt aaagaaggga aaatgataca
     4321 taaaatagtt gatgcattag aagtatttgc agatgctatt gtaacattgg atgaagaaca
     4381 agaagaactt caagattttg ttgaatctat agatgaagat ttagcagatt tagaagaaga
     4441 tattgctgac atggaagaag atctttatga agaagatgac gatgaggatg atgaggactt
     4501 cagctatata gaaatggaat gcccaaattg tggagagtta gtagaaatag acgaagattt
     4561 gttatatgat gatgaagtag atgttgtttg tcctgattgt aaggctgtga tattatcatc
     4621 agaagatgat tgtgatgatg attgtacatg tggtggttgt tcaagttgtg atgatagaga
     4681 gtaaaaattc ataagaatta aaactgccta tgatgcctat gagatatttt gcttcatagg
     4741 tagttttatt tttatgagga agggtattat gtattttggt tttgcaatac ttggacaaaa
     4801 atagtacact agaatttata gaataggatt ttggagggat gtaaatatga aaataagtaa
     4861 aaaattacta gataatatac aaagatttga aaatgttata aattataaat ttaaaaataa
     4921 agaatatata ctagaagctc ttactcatag ttcatattct aatgaaaata aaaaatataa
     4981 ttttaacgaa agattggaat ttttagggga ttcggtttta ggcatagtga taagtgatta
     5041 tttatttaat gaagaagcta atctgcccga aggggaacta actaaactta gagcaaatat
     5101 agtttgtgaa gattcattaa gtgaagtagc taatgatata aatttaggta ttcacatgtt
     5161 attaggtaga ggagaagaag caacaggagg aagacatagg acttcaatat tagcagacgc
     5221 atttgaagct gtaatagctg ctatatatct tgatggaggt tttgaaagtg caagacagtt
     5281 tatacttcat catatggaaa atataattta tgattcaaga aaaggaaata tatttagaga
     5341 ctacaaaacg catcttcaag aggtgttaca agggaatgga gaaaataata tctggtacag
     5401 gcttatagaa gaaaaaggac cagaccataa taaaagattt gtaatggaag ttggaattaa
     5461 tgacgatgta cttggtatag gagaaggcaa gagtaaaaaa gaagctgaac agttagctgc
     5521 taaaatagct ttaaagaaaa aattatggga aaaataaata taatatgtaa aaatataaaa
     5581 agaaatattt atattagaag gatgttgtag atgaaaaaga gaattatacc tatatttgtt
     5641 cctcacaaag gatgtcctca tgattgcata ttttgtaatc aaaaaaaaat aacaggtgtg
     5701 agtactgatg ttactagtga agatgcaaga aatataattg aggaatgttt agagactata
     5761 gataaagatg cagatgtaga aatagcattt tttggtggta gctttactgc tatagatatt
     5821 gatatacaaa aaagtttatt atcagttgct aaagaatatg tagaaaaagg tcttgtaaaa
     5881 gatattagaa tgtctacaag accagattgt attgatgaag atatattaag tatgttaaaa
     5941 gaatataaga caagtataat tgaactagga gtacaatcct tagatgaaaa agtattatta
     6001 gatagtataa gaggtcatca atctgaaatt gtatacaaga gttcaaagat gataaaaaat
     6061 agtggaatca aacttggatt acagatgatg attggtcttc cagctgacac agaagaaaag
     6121 tgtatattta cagcaaaaaa atttgtagag ctaaaaccag attgtgttag agtctatcca
     6181 actttggtag taaaagatac aggtcttgaa aagttaatgg aacaaaataa atataatcca
     6241 tttactcttg aagagagtgt aaatatagta aaaaaagttc ttgtactgtt ttatgttaat
     6301 aatatcaatg taataagagt tgggcttcaa gctactgatg atatacaaat tggaaaagct
     6361 gttttagcag gaccatatca tcctgcattt agagagttgg tagaagcaga tatgataaaa
     6421 gattatttag aatttgttat tttgcaaaat aaaaatataa agcaaatgtt ggtcaaatct
     6481 aataaaaaga atatttctaa aatcatagga aataaaaaaa caaatgttaa atatatggaa
     6541 gaaaaatttg gtgtgctttt aaaaacacaa gaatcagatt tagatataaa tcaattagaa
     6601 attgtgttag atgggaaaag tttaattagt gctaatatga gagacattca tagaaaattg
     6661 tatgacattt atgaccttta gttttaataa tgaagggaga gaaaagattt gtatttaaaa
     6721 agactagagt taaagggatt taaatccttt ccagtaaaaa cagatattat ttttaaagaa
     6781 ggaataacag ccatagtagg accaaatggg agtggaaaaa gtaatatatc tgatgctgta
     6841 agatgggtat taggagaaca gagtattaag agtcttagag gtgataaact cgaagatgta
     6901 atatttgcag gtacagatac aaaaaaacct atgaattatt gtgaagtggc tcttactatt
     6961 gataattctg aaaatcaatt ggaattagat tttacagaag taactataag aagaagggct
     7021 tatagaaatg gtgaaagtga attttttcta aataataaaa gttgtagatt aaaagatata
     7081 aaagaagtct ttttagatac tggtattgga aaagatggtt attcaatcat agaacaagga
     7141 aaagtagatg aaatattaag taataatcct ttaagcagaa gaaaagtttt tgatgaagct
     7201 tgtggcatat caaaatatag atataaaaaa caggaagcag aaaggaattt aagtaataca
     7261 aaggaaaatt tagaaagaat agatgatgta tatatagaaa ttgaaaatca attaaagcct
     7321 ctttttaatc aacagacaaa ggcaaaaaag tacttggaaa taagtgaaaa attaaagaca
     7381 cttgaagtaa atagctttat aagagaaatt gaaggaatag aaaaagaatt aagtgaggtt
     7441 aatgaacatc gtaaggttat tgaaaaggag ctcaatgaaa aagaagaaca aaaaaatgtt
     7501 gtagagaaaa agcaagaaga tattaataaa gaggtagagg tattacaaga tgtaattgaa
     7561 aaatctgtag attatataaa ttcaattaaa ggagttatat caaaaaaaga gtcccaaata
     7621 aatttaatta aggaaagaat aagaaatttt acgaatgaaa ttagtagaaa aaatttagaa
     7681 ataaaggata taaaagagaa gctaaatgaa aataagcaat acataaaaga attagaaagc
     7741 aataaattat caggtagtga agaactatct accttgcagg aaaatataaa agtattggaa
     7801 ggaagtaaag ataaacaaaa aattaagtta gaatccctaa ataatgagat agaattattg
     7861 aaagaaagta taattgatat attaaataag aaacaagagt ttagtaataa gctgtctact
     7921 ttaaacgcaa ataaagaaaa tatgaatatc agagatgaaa atataaattc agagataaca
     7981 gagttaaaca aaaatattga aataaaatca tctgaattag atactataaa taaagaattt
     8041 aatatgcaaa atgaaaattt aaagaatgta aataatagac ataaagaatt atcaattaat
     8101 ttgcaggatt caattagtga acacaataaa ctagaagatg aaatacagaa aagtaaatat
     8161 aatttaaatg gatataattc aaagttaaat gtctatatag atatggaaaa tcattatgaa
     8221 ggatttaata gaggagtaaa agaagtacta aaaaataaaa atttaaaagg agttcatgga
     8281 gcattaggac agattataaa tgtacctgaa aagtatgaga aatctataga agcagctctt
     8341 ggtgcttata tgcaaaatat aataactgat aatgagttta gtgctaagtt tgcaataaac
     8401 tatctaaaac agaataattt aggtagagta acatttcttc cattaaatat aattaaatca
     8461 aataaaataa gtctaggaaa tttaaaagca aatactaagt tcataggaat agcaagtgat
     8521 ttaattacat ttgatgaaaa gtatagaaat ataattgaaa atatacttgg aagaacaata
     8581 cttataaata atatagatga gggcataaaa tttgcaaaag aaactggtca taggtttaaa
     8641 atagtaactt tagatggtga aatcttaaat ccaggaggtt ctttgactgg gggaagtcta
     8701 aaaactaatg ggaatatact atcgagaaaa agatacatta atgaatatac agaaaagata
     8761 agtaatatca agaatgaaat ttcacatcta gaattaaaaa gagaatcttt agacaaagat
     8821 gtgaaaaata tcaaaaatga aattgattca catgaaagta aaataaaaga tttagaaaaa
     8881 agtataataa taaaaagtac aagtataaag aatgttgagt ctgaaattga atcgttaaaa
     8941 ggtagtatta ctaaattaga aaatgagaag aatgatttaa attctaacct aaattataca
     9001 cttgaaaaaa gtgatgatgt tagaaaagat atggaagagt tagatgattt atacaataaa
     9061 aataaagaaa aaattgatgc attgaatgag gaaataaaaa gatacaatga tttatatgat
     9121 aaagaaaaat ctgaatttga tgaattgaac ttaagtttag tgaagaaaac agaagtttac
     9181 aatagtatag ttagagatat aaaaagaata tctggtgaaa attgtgagct agaagaaaaa
     9241 aataaacaat tagaagagtc attaaattat gaagaacatg aaataattaa attacaagat
     9301 tctatactca ctgaagaaaa agaaaaagaa aatttaacaa aacaactagg ggatagtaat
     9361 agaaatcttg aaactagaaa aatagcaaaa gatgatttaa aaaatagttt tgatgaaatt
     9421 aataaagaat taaaaactat agatagacag catatagaac ttaaagaaag tttatttaaa
     9481 gttggtggaa gattagaaag attaaaaact agtcaagaca catatataaa taagttgttt
     9541 gagcaatatg atatgacctt agtacaagca ttggaaatta aagatgaaga tttggatata
     9601 gatagaaaat tcttagaaag tctaaagaga gaaataagaa gtcttggaaa tataaatata
     9661 gactctataa aggaatatga ggaaataaaa gaaagatacg atttttatag cgaacaaaag
     9721 caagatttag aagagtctat ggaagagata gaaaaactta tacatacttt agaagaaaat
     9781 atgaaatctg aatttgaaat taagtttgaa gaaataagta aaaattttaa atatgtatat
     9841 aagagattat ttggtggagg ttgtggagaa ttaactattt tagataaaga aaatttatta
     9901 gaaagtgata tactaataac agctcaaccc ccaggtaaaa aaatgaaaaa tttaaaccta
     9961 ttatctggtg gagagaaagc tttaacggca ataagtatat tatttgctat attgattaca
    10021 aagccaacac cattttgtat attagatgag attgaagcgc cacttgatga cgcaaatata
    10081 tttagatttg gagaattttt gaaggattta tctaaagaga ctcaatttat atcagtaact
    10141 cataggagag gaacaatgga agctgctgat tatatctacg gagttacaat gcaagaaaaa
    10201 gccatttcaa aagttattag tttaaaatta aaagaagctc aggaaataac agatattata
    10261 taacttagat tgacatagga ggaataacag tgttaaaaaa attatttggt tttggaaaag
    10321 acaaggaaaa ggaaatagaa aaaaaagatg ctgaagaaga aatagaagtt gaagacagtg
    10381 ttgataattt agaaaacttg gaagaaacta ttttttcagg acttgaagaa gaagtgatag
    10441 ataaagtgga agatattgaa gaaaaaaatg aggaaagtgt caataatgaa ggcactgaag
    10501 aaatcgaaaa ctttgaaaaa atagaagttg agatggatag taatggaaaa gaagtagaaa
    10561 atatttcaaa taatgattct caagaagaga taatcgaaga attagaaaat tatgatgaaa
    10621 ttgagtctaa agagatagaa gataaagaag ataagaaagt taacttgttt gaaagactaa
    10681 aacaaggatt gacaaaagca aagcaaggaa taactgatag aatagatgaa gttttaaaat
    10741 catatacaaa aatagatgaa gaattacttg aagatttaga ggaaatttta ataacagcag
    10801 atgttggtgt aaatacaact atggatataa ttgaaagact aagagataaa ataaagcaaa
    10861 aaggtattac tgaaccaata aaggtaagag aagaacttaa atctatagtt gaagatattc
    10921 ttacaaatga aaactctaca ctagatatag aaccagcacc atgtataata ttaatggtgg
    10981 gtgtaaatgg ggtcggtaag actactacaa taggtaaact agcaaataga tacaaaaaag
    11041 atggtaaaaa agttttatta gcagcagcag atacatttag agcagcagcg acagagcaat
    11101 tagaaatttg ggcaaataga accaatgtag acataataaa acatcaagag ggagcagacc
    11161 ctggagctgt agtatttgat gctataaaag ctgcaaaagc tagaaaaaca gatgtattaa
    11221 tatgtgatac agcaggaaga ttacacaata aggctaatct tatgaatgaa cttggaaaag
    11281 tatttaaaat agtagataga gaatttccag aagcaaaacg tgaagtactt cttgtggtgg
    11341 atgctacaac aggtcaaaat gcagttgttc aagcaaagac atttaaagaa gttgcagata
    11401 taacaggtat agtacttaca aaacttgatg gaactgcaaa aggtggagta gtccttgcag
    11461 taaaatcaga agtagatgta cctgtaaaac ttattggagt tggagaaagt gtagaagacc
    11521 tacaagattt caatgcaaaa tcattttcag atgcattatt tggtaactaa tgttctttta
    11581 aaaataatgg ttgacaagag tgttgttatg atataaaata caatagtgta aagtaaataa
    11641 cctttacagt atactgctag gaagtgtaag atatgaatat agaaaaaatg gtcgaaattg
    11701 gattgttatt tgaacagtat aaagaattat taactgacaa gcagaaagaa atagttgctc
    11761 tatactatga agaagattat tctttaggtg aaattagtga aaatctgaat gtatcaagac
    11821 aaggtgttta tgatacctta aagcgttcag aaaaaatact aagagattat gaagaaaagt
    11881 tacacttagt atcaaagatt caagagcagg aaaaaaatat taagattata aaagataaaa
    11941 ttattgacat taaagaagat ttattgcaca atagagattg tgctaattta atccctaagc
    12001 tagaaaatat agaagatgta tgtagggaga tgataaaatg atatttgaag gattgtctga
    12061 taaactacaa ggggcattta gtaagttaaa atctaaagga aaacttacag aagtagatgt
    12121 aaaaaatgct atgagagaag ttaaacttgc tcttcttgag gcagatgtta actttaaagt
    12181 agttaaagat ttcataaaaa aagttcaaga gagatgtgtt gggcaagaag ttatgcaaag
    12241 cttaactcca gctcagcatg taatcaaaat tgtaaatgaa gagcttacaa gtttaatggg
    12301 agatgtacaa agtaaagtaa tgatttcctc aaagcctcct acaattttaa tgatggttgg
    12361 attgcaaggt gcaggtaaga ctactacagc aggaaaactt ggaggatatt ttaaaaagca
    12421 aggtaaaaaa cctctattag tagcttgtga tatttataga ccagcagcta taaagcaact
    12481 tcaagttgtt ggagaaaaat tggatatacc tgtattcaat atgggagata aagaaaatcc
    12541 aataaatatt gcgaaagcag gtttaagcca tgcgattaaa aatgctaatg atttagttat
    12601 tatagataca gctggtagac ttcatataga tgaagtactt atggatgagt taaagtctat
    12661 taaatcagaa gttaagccac atgagatact tttggttgta gattctatga caggtcaaga
    12721 tgctgtaaat gttgcagaaa gcttcaatga ggcacttggt gttgatggag tagtattaac
    12781 taaattggat ggagatacta gaggtggtgc tgcgctttca ataagagcag ttacacaaaa
    12841 gcctataaaa tttatgggga tgggagaaaa gctagatgat atagaacctt tccacccaga
    12901 tagaatggca tcaagaatat taggtatggg agatgtctta agtttaatag aaaaagcaca
    12961 agaaaatata gacttagaga aagctaaaga attagagcaa aaaattaaaa aacaagagct
    13021 tgattttgaa gatttcttac aacaaatgga acaaatacaa aatatgggac ctcttgacaa
    13081 gatacttggt atgatacctg gtatgggaaa tgtaaaagac caacttggag atgtagattt
    13141 gaatggcaaa gaaatgaaga gaacaaaagc cataattcag tcaatgacta catatgagag
    13201 aagaaaccca ggagtattaa atgcttcaag aaagaaaaga atagctaaag gcagtggaac
    13261 tagtgtacaa gatgtaaata gacttataaa acaacttaat gaaatgaaaa aaatgatgaa
    13321 gatgtttgct ggttcacaaa agagtatgaa gaaaaggggc ggcttaggcg gtttaccttt
    13381 ttttaaataa aatataaaaa agtaaaaatt attcggaggt gactgtaatg gcagttaaaa
    13441 taagattaaa aagaatggga gctaacaaaa aacctttcta cagaatagta gtagctgatt
    13501 caagagctcc aagagatgga aaatttatag aagaaatagg atactataat ccaatttctg
    13561 aacctaaaca agtaagaata aatgatgaaa aagctataaa atggttagct actggtgctc
    13621 agccaacaga agtagttaaa aaattacttg taaaaaacgg agtaatagaa aaattcgaag
    13681 cttctaaaca agcaaaataa ttttttcttg gcaattagtt taagtaaggg ctcattgcta
    13741 aggttacttt aggagatgaa atatatgaaa gagctagttg tagatatagc taaggctcta
    13801 gttgataatc ctgactcagt tgttgttgag gaatttgaag ataatgatgg tatcgtctta
    13861 aagcttacag ttgctcaaga ggatatgggt aaggttattg ggaagcaggg aagaatagct
    13921 aaagctataa gaactgtcgt aagatctgtt gcaaatagag aaaatataaa agtttctctt
    13981 gagatagtat aaaataggag gattaggtat aatgcctagt cctttttata taaatgcgta
    14041 gtttaagatt ttatgatgat atgaccacat aagattaaat tttttaagaa ggtgataaca
    14101 tgaaagaaaa attaactcat tttaaggtag gtcaaatagt aaatacacaa ggtttaaaag
    14161 gtgaagtaag agtttatccg cttactgatg atatagagag gtttgatgaa ttaaaagatt
    14221 tctatctggg aaaagattta aataataaat tggctgttga aaaagtaaga tacaaaggtt
    14281 ctatggttat aatgaagata aaaggcatag acagcataga gaaagcagaa aaactaaaaa
    14341 ataaatttat gtatgtagct agagaagata gcagagagct tgaagaaggc gaatttttta
    14401 tagcagatat gattggaatg gaagttttaa ctgtagatgg aaaatatgta gggatactag
    14461 aagatgttct tcaatactca gcaaatgatg tctatgtagt aaaaggtgag gaagataaag
    14521 aatttatgat accagctata aaaaaatttg tacctacaat agatattgat gaaagaaaaa
    14581 tgattataga ccctattaag ggaatgatag attaggtggt aatatgagat ttcatataat
    14641 gacacttttt ccagaaatat ttaattcgta catggatgaa agtataatga agagagcagt
    14701 tgaaaaaggt ataattgagg ttcatatata taatataagg gatttttcta ataataaaca
    14761 taaaaaagta gatgattatc catttggagg aggagcgggg atggtaatga ctcctcaacc
    14821 tatatatgac acatataagc atataataac aactcataat ataaataacc caagtgtaat
    14881 ttatcttact ccaaaaggta aggtatacaa tcaatctatg gcaaagcaga tgtctttaaa
    14941 agaagatata atactactat gtggtcatta tgaaggaata gatgagagaa tcattgattt
    15001 aatagttact gatgaaattt caattggaga ttatgtatta actgggggag agctcccagc
    15061 acttataatg atagattcta tatcgagatt aataccaggt gtattaaacc aagaagaatc
    15121 atttgaagaa gaatcattta aagacaactt attggaatat cctcattaca ctagacctag
    15181 agattttgaa ggattaaaag taccagaagt gcttttatca gggaatcata agaagataga
    15241 tgagtggaga agagaagaat ctataaggat aaccaaagaa agacgatttg atttatataa
    15301 aaaatctaat gaaaaataaa aatataatga aaaattaata tatatgtata caataaagta
    15361 cctataaatg gaattaaaaa cataaaagtg cttgtaataa ctattgaagt atagtataat
    15421 ataaaatgtt gaaaatacgg gcgttcctct gtttacactg gtcgggtagt taagaacgtc
    15481 tatgatatct aggaggaaga aagatgaatg aaatgctaag agcaattgag caagaacaat
    15541 taaaaaatga agttcctaat tttggacctg gggacacagt taaagtacac gttagaatta
    15601 tagaaggaaa aagagaaaga atacaagtat tcgaaggtgt agtattaaag agacaaggtg
    15661 gaggagcaag agaaactttc acagttagaa aaatgtcttt caatgttggt gtagaaagaa
    15721 ctttcccagt tcactctcca aaaatagaaa aaatagaagt tactagaaaa ggtaaagtaa
    15781 gaagagctaa actaaactac ttaagaggta gagtaggtaa agctgctaag ataaaagaag
    15841 ctagaaataa ataattaaaa actttactta taaatggggg gctgatttat cagtcctctt
    15901 tctattttaa tgaaaattac agcaaataat tatactagaa ataaatagaa atatttgttg
    15961 aaaatataca ttatttatct atgaatttat agcttttaaa atgaaaaata aaattggtaa
    16021 atattgcatt atattttgta acaatattaa aaataagaga acagtattat gtaaagtatg
    16081 acgttaaaaa gatgacaata ttatagtttg ttaagataga ttttttaagt ggaattagga
    16141 tataataata taatattaat aaggagtgat acatgtgtca aatgaatacg aagagtatct
    16201 tatgaatgac aatctacata taaactggta tccaggtcat atgaaaaaaa ctaaggagtt
    16261 agtaaaaaat aacttaaaat tgattgatgt agtaattgaa cttttggatg ctagaatccc
    16321 gtttagtagt aaaaatccag acatagacag gcttgtagga gataagccaa gagttgtcgt
    16381 acttaataag agtgatatgg cagataggga taaattgaat caatggattg aatactataa
    16441 gaaaattaat atcaaagcta taccagtaga tacaataaaa ggcgttggta taaataagat
    16501 aatcgaagaa tgtaaaaatg taactagaga aaaaatgagt tctttaaaag acaaagggag
    16561 aaaagaaaga gctatacgaa taatgatagt tggagttcca aacgttggta aatcgtctct
    16621 tataaacaaa ttaacaggta gaaaaagcac tcaaactgga gataagccag gagtaacgaa
    16681 agggaaacaa tgggttagat taaagggaaa tcttgaactt ttagatacac ctggaatact
    16741 ttggcctaag tttgaagacc aagaagttgc attaaattta gcatttagta gagctataaa
    16801 ggatgagatt ttagatactg aaactttggc tttaagactt atagagaaac ttatgaaaat
    16861 agaacctgag aagttgaaag ccagatataa gttagattgt ctaggagaaa ctccaattga
    16921 aactatggat atgattggcc ataaaagagg gtttataaca ggtaaaaaag aactagatta
    16981 tacacgcata gccacaactg tattaaatga atttagagat ggaaaaatag gaaatataac
    17041 attggaagtt ccagaaaacg ttaaaagata gattttaaaa caaaatcaaa aatttaatgt
    17101 taaaaattta aaaaagcctt ttagcaaagg cttttttatt tttttgaaat atagacaaat
    17161 atctccatat aaaagtataa attaggttag aaaaccttta aaaatattaa tttaagacaa
    17221 atatacctaa tattttgaaa attaaaatga gtgtgattat ttaaaatttt agcatattga
    17281 cttgcttgtt tcgtataata tataataagc acaaataaat acaatatatt aaaaatttaa
    17341 tttatttaat tttattaatt taataataag ttcttattgt ttaattcaac ttacttatgc
    17401 aagcgtaaac aatcgagaca ttttattaat ttaataaggt taaaaagggg gattttataa
    17461 tgggtaagac caaggatgtt atagtatttg gatttgcgtt atttgcaatg ttctttggag
    17521 caggtaactt aatatttcca ccttacttgg gaataattac aggtccagaa tggttaattg
    17581 ccttcttagg atttacgttt gctgatgctg gattggcact tctagcagta atggctacag
    17641 ctaaattcga tggaaacgta gttgaaatgt ttaaaagatg tggtatgaag ttaggaattc
    17701 ttataggttg tgcagatatt ttatgtatag gaccattctt agctatacca agaacaggtg
    17761 caacaactta tgaaatgggt ataatgcctt tgtttggaac ttcaattcca gtgttattat
    17821 tctgtatact tttttttgcg atttcatatg tactaacaat aagaccttct aaggtcgtag
    17881 atatagttgg acagttttta actccagctc ttctaatagc tttagcattt ataattataa
    17941 aaggtattat atcacctctt ggagatatag tagataaacc tatgatacct aatgtatttg
    18001 cagaaggtat aggtcaagga tatcagacaa tggatgcttt tgcagcaata gcacttgcat
    18061 cagtgctaat agtatcttta aatgataaag gatattctac tattagtgac aagttgaaaa
    18121 tgattggtaa ggcgggtgtt cttgcttgtg gaggattagc tctagtttat ggaggattat
    18181 gtttccttgg ggcaactgta tcaacaatgt atggaacaga tgcagtacaa tcacaagtaa
    18241 tagtaaatat aactgaagga ttgcttggaa atgttgggaa agcgatttta gcagtagtag
    18301 tatcattagc atgtttaact acatctatag gtcttacatc tgccacaggt caatatttct
    18361 ctagacttac aaaaggtaaa ttgagttatg aaaaaatagt attagctgta tctgtattca
    18421 gtgcagtagt agcatctttt ggtgttggaa ctataataaa gatagcatct cctatactaa
    18481 gtatagttta tccaccatca attgttttaa taattttagc tttcttcaat gaaaaaatta
    18541 agaatgataa tgtatacaaa ggagcagtat atatgtcatt gtttgtaagt atactaacag
    18601 ttatatctag ttatggagta gctgttccag tagtaaattc tttacctctt aattcattag
    18661 gatttaactg ggtggtgcca gttataatag ctggaataat tggtaatttt ataccatcaa
    18721 agagtcaatc taatacactt ggaacaaact aagttttgtt taattaaaat ataatcaatt
    18781 gtaaataaat gagttaacta aaagtaaaag gagttatttg ta
//
LOCUS       DAYAOO010000079        18797 bp    DNA     linear   BCT 12-OCT-2024
DEFINITION  TPA_asm: Clostridioides difficile isolate ST8-SSI-h139-18
            SAMN40601845-rid21577343.denovo.079, whole genome shotgun sequence.
ACCESSION   DAYAOO010000079 DAYAOO010000000
VERSION     DAYAOO010000079.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN40601845
            Sequence Read Archive: SRR28438827
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 18797)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 18797)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-MAY-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-MAY-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002157583.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002157583.1
            Genome Coverage       :: 163x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/11/2024 16:19:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 4,038
            CDSs (total)                      :: 3,963
            Genes (coding)                    :: 3,930
            CDSs (with protein)               :: 3,930
            Genes (RNA)                       :: 75
            rRNAs                             :: 6, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 60
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 33
            CDSs (without protein)            :: 33
            Pseudo Genes (ambiguous residues) :: 0 of 33
            Pseudo Genes (frameshifted)       :: 7 of 33
            Pseudo Genes (incomplete)         :: 25 of 33
            Pseudo Genes (internal stop)      :: 11 of 33
            Pseudo Genes (multiple problems)  :: 8 of 33
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..18797
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN40601845-rid21577343.denovo.079"
                     /isolate="ST8-SSI-h139-18"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Denmark"
                     /collection_date="2018"
                     /collected_by="Statens Serum Institute"
     gene            complement(163..1524)
                     /gene="rlmD"
                     /locus_tag="ACGI5H_002984"
     CDS             complement(163..1524)
                     /gene="rlmD"
                     /locus_tag="ACGI5H_002984"
                     /EC_number="2.1.1.190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417358.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008649 - rRNA methyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (uracil(1939)-C(5))-methyltransferase
                     RlmD"
                     /protein_id="HFG9698680.1"
                     /translation="MSVKKKDVIEFEVDKMEFGGTSLSQVGDRVIHMKGGISGQKVRA
                     GVKKVRSKKAEVKMIELLENSPLETEETCKHFRECGGCTLLSVPYEKQLEIKEKQVMD
                     LFLKQDLFGFQFLGIEGSPENKYYRNKMEYTFGDEVKNGPLTLGLHKKGKHIDIQTVE
                     ECMLVDEDFSKILVSSVEFFNEKKLPYYRTMNHKGYLRHLVVRKGIHTNEIMVNIVTS
                     SQEDFDMYEFKDMLLGIDLKAELVGVLHTINDGLADAVQCDELRVLYGRDYIQEEILG
                     LKFKISPFSFFQTNTKGAEVLYSIARDFIGDYNDKVVFDLYSGTGSIGQVMAGAAKKV
                     YGIEIVEEAVVAANENAKLNGLTNCEFIAGDVAKVVKDLKDKPDLIIVDPPRPGIHKD
                     AIRDICGFGAKEIVYISCNPKSLVVDLVDFKGYGYEIKMVKCMDMFPNTPHCETVVLL
                     RRK"
     gene            complement(1551..2273)
                     /locus_tag="ACGI5H_002985"
     CDS             complement(1551..2273)
                     /locus_tag="ACGI5H_002985"
                     /EC_number="5.4.99.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860778.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0009982 - pseudouridine synthase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pseudouridine synthase"
                     /protein_id="HFG9698681.1"
                     /translation="MAKKQRIDKILSNLGYGSRSEIKKYCKQGSVVVNGSEVSNPGTQ
                     VDTENDEILFNGEEVIYREYIYLMMNKPDGYISATTDKYDPTVLDLIDLSYLAFEPFP
                     VGRLDKDTEGLLVLTNDGKLSHRVLSPKKHVPKTYYAKIDGVVTEEDVEAFLEGVVLD
                     DGYKTMPSQLNILKSDDESEIELTIHEGKFHQVKRMFESVGKKVVYLKRLSMGNLKLD
                     ESLELGEYRELTDEEVKLIEER"
     gene            complement(2273..2602)
                     /locus_tag="ACGI5H_002986"
     CDS             complement(2273..2602)
                     /locus_tag="ACGI5H_002986"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1904 domain-containing protein"
                     /protein_id="HFG9698682.1"
                     /translation="MPQIKIRGINENDICKISEKMINDLVEAVKCPRDYFEIECIKSV
                     AIRDGKIADVYPFVEVAWFDRGQEVQDIVARIITDSIRNNLDVESIDLAFTVFEKEKY
                     YENGEHF"
     gene            2932..3858
                     /gene="fba"
                     /locus_tag="ACGI5H_002987"
     CDS             2932..3858
                     /gene="fba"
                     /locus_tag="ACGI5H_002987"
                     /EC_number="4.1.2.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860777.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004332 - fructose-bisphosphate aldolase
                     activity [Evidence IEA];
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA];
                     GO_process: GO:0006096 - glycolytic process [Evidence
                     IEA];
                     GO_process: GO:0030388 - fructose 1,6-bisphosphate
                     metabolic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="class II fructose-1,6-bisphosphate aldolase"
                     /protein_id="HFG9698683.1"
                     /translation="MALITTKEMFKKAYEGGFAIGAFNISDLEQLQGVLKAAKAKNSY
                     VMIQASMSAVKYAGPHTLVEMVKAASDEIGVDVALHLDHGPNMDAIKTCIDAGFSSVM
                     IDGSHFDFEENVRITKEAVEYAHSKGVVVEAELGVLAGTEDDVTSDVHKYTQPAEAVE
                     FVERTGVDSLAIAIGTSHGAFKFKGEAKLRFDILEEIQSKLPGFPIVLHGASAVDQNA
                     VATCNEFGGNIAGAKGVPVDMLRKASSMAVCKINMDTDLRLAMTAAIRKFLAENPKEF
                     DPRKYIGAGRDAIQAVVESKIDDVLGSANSIN"
     gene            complement(3993..5624)
                     /locus_tag="ACGI5H_002988"
     CDS             complement(3993..5624)
                     /locus_tag="ACGI5H_002988"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434571.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0008134 - transcription factor binding
                     [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sigma 54-interacting transcriptional regulator"
                     /protein_id="HFG9698684.1"
                     /translation="MDNNLIGLIEHVENPAILCKESGEIIYCNHLIDSIFSFLDIKKP
                     RNINELDSNFDKTEILTDSKKKIAFRELRMTAHIYNMKDNNNENNIVYLFEKSLISDK
                     VIEDIIEHIDEVVVVFNKDGVIEKMNTVSDEILPFKRTEVLGRNITDLVRQGLVEEPI
                     ILNMLKVKKKIYRNIVYPDGKLIAYTAVPRWDSKGKLTGGVLTGRDISRVIKLESQIK
                     YSDISEDTEYISQSKIMDNIKKVVKRAAASDSSIFINGESGVGKEIIARTIYKYSSRR
                     DKPFIAINCGAIPNELLESEFFGYEEGSFTGAKKKGKKGLFEEANGGTIFLDEIGELP
                     MQMQKKLLRVIQENTITRIGGSKPIKIDVRYISATNISHEDLRNNLKFRQDLYYRLSV
                     IPVKIPPLRERKEDIVPLVNYFLKLYNEKYNREVEVSPKVIELLEEYSWPGNIRELKN
                     IIERFVVLSAKNVIGEDEFNMLINLDMIDNETDDLSPIVVNGIMNLNDAYKIVDQIMI
                     SKAINKYGSITKAAEVIGIYPSTIHRKIKSGHIHV"
     gene            complement(6107..7144)
                     /locus_tag="ACGI5H_002989"
     CDS             complement(6107..7144)
                     /locus_tag="ACGI5H_002989"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417347.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0009055 - electron transfer activity
                     [Evidence IEA];
                     GO_function: GO:0050660 - flavin adenine dinucleotide
                     binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="electron transfer flavoprotein subunit
                     alpha/FixB family protein"
                     /protein_id="HFG9698685.1"
                     /translation="MNDIKDLSSYKNVWIFAEQREGKIAPVVIELLGEGRKLAKEVDA
                     ELCAILLGKDVDGLAKELITFGADKVYVADDALLEKYTTDAYTKVIKDAIDEIKPEIM
                     LFGATHIGRDLAPRIASRVGTGLTADCTKLEIDPEDKKIKQTRPAFGGNIMATIICPN
                     HRPQMSTVRPGVMDKAEKDETRTGEVIALDYKITQDDIRTTVLETVKTKKDLVSLTDA
                     NVIVSGGLGLGGPEGFEMLKKLADKLGGVVGSSRAAVDAGWIDHSHQVGQTGTTVKPN
                     LYIACGISGAIQHLAGMQSSDFIIAINKNPAAPILEIADYGVVGDLHEIVPMLIEKLD
                     SVDDLLEAIKA"
     gene            complement(7163..7948)
                     /gene="etfB"
                     /locus_tag="ACGI5H_002990"
     CDS             complement(7163..7948)
                     /gene="etfB"
                     /locus_tag="ACGI5H_002990"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728584.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="electron transfer flavoprotein subunit beta"
                     /protein_id="HFG9698686.1"
                     /translation="MKILVCVKQVPDTNEVRINKETGTLIRDGVPSILNPDDANALEE
                     ALKIKDEHDDVTITVITMGPPQADFMLRECLAMGADDAILLSDRAFGGADTWATSNTI
                     AAGISKVGDYDIIFAGRQAIDGDTAQVGPQIAEKLDIPQVTYVQDFKIEGKDIIVQRQ
                     LEDGYELIKVSTPVLLTAVKELNTPRYMSVDKIVKAYKHDVKVWTIDDLDVNKEEVGL
                     KASPTKVFRSFTPEPRGKGEILEGKADEIASKIIIGLKQKHII"
     gene            complement(7981..9114)
                     /gene="acdB"
                     /locus_tag="ACGI5H_002991"
     CDS             complement(7981..9114)
                     /gene="acdB"
                     /locus_tag="ACGI5H_002991"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427762.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative isocaproyl-CoA dehydrogenase AcdB"
                     /protein_id="HFG9698687.1"
                     /translation="MLYNKEQELLRKAVRDFVSKELDTLPAEMDKTGVMPKELIKKLA
                     DAKFISSNIPEEYGGGGAGYVSYAIVMEEIARRCASTATFVTAGSSLASLPILYNGTE
                     EQKQKYLKGIATGELIGAFGLTEPGAGSDAGGQQTTAELVGDHYILNGRKTFITNGPF
                     CDVAIVIAVTDRSKGLRGTSAFIVESKWDGFSTGAHEDKMGIRGTETSDLIFENVKVP
                     KENLLGKEGQGFKIAMGTLEVGRIGVAALALGIAQGALDEAVKYTKQRVQFGKPIAKF
                     QNTQFTIADMETKVCAARGLVYDAAQKRDAGMRVAQESAMAKYYASEIANEVAYKALQ
                     LHGGYGFIKDYEIERMYRDARIVSIYEGTSEVQKMVISSNVLK"
     gene            complement(9162..10289)
                     /gene="hadC"
                     /locus_tag="ACGI5H_002992"
     CDS             complement(9162..10289)
                     /gene="hadC"
                     /locus_tag="ACGI5H_002992"
                     /EC_number="4.2.1.157"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427763.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="(R)-2-hydroxyisocaproyl-CoA dehydratase subunit
                     beta"
                     /protein_id="HFG9698688.1"
                     /translation="MEAILSKMKEVVENPNAAVKKYKSETGKKAIGCFPVYCPEEIIH
                     AAGMLPVGIWGGQTELDLAKQYFPAFACSIMQSCLEYGLKGAYDELSGVIIPGMCDTL
                     ICLGQNWKSAVPHIKYISLVHPQNRKLEAGVKYLISEYKGVKRELEEICGYEIEEAKI
                     HESIEVYNEHRKTMRDFVEVAYKHSNTIKPSIRSLVIKSGFFMRKEEHTELVKDLIAK
                     LNAMPEEVCSGKKVLLTGILADSKDILDILEDNNISVVADDLAQETRQFRTDVPAGDD
                     ALERLARQWSNIEGCSLAYDPKKKRGSLIVDEVKKKDIDGVIFCMMKFCDPEEYDYPL
                     VRKDIEDSGIPTLYVEIDQQTQNNEQARTRIQTFAEMMSLA"
     gene            complement(10289..11515)
                     /gene="hadB"
                     /locus_tag="ACGI5H_002993"
     CDS             complement(10289..11515)
                     /gene="hadB"
                     /locus_tag="ACGI5H_002993"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888224.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="(R)-2-hydroxyisocaproyl-CoA dehydratase subunit
                     HadB"
                     /protein_id="HFG9698689.1"
                     /translation="MSEKKEARVVINDLLAEQYANAFKAKEEGRPVGWSTSVFPQELA
                     EVFDLNVLYPENQAAGVAAKKGSLELCEIAESKGYSIDLCAYARTNFGLLENGGCEAL
                     DMPAPDFLLCCNNICNQVIKWYENISRELDIPLIMIDTTFNNEDEVTQSRIDYIKAQF
                     EEAIKQLEIISGKKFDPKKFEEVMKISAENGRLWKYSMSLPADSSPSPMNGFDLFTYM
                     AVIVCARGKKETTEAFKLLIEELEDNMKTGKSSFRGEEKYRIMMEGIPCWPYIGYKMK
                     TLAKFGVNMTGSVYPHAWALQYEVNDLDGMAVAYSTMFNNVNLDRMTKYRVDSLVEGK
                     CDGAFYHMNRSCKLMSLIQYEMQRRAAEETGLPYAGFDGDQADPRAFTNAQFETRIQG
                     LVEVMEERKKLNRGEI"
     gene            complement(11530..12330)
                     /gene="hadI"
                     /locus_tag="ACGI5H_002994"
     CDS             complement(11530..12330)
                     /gene="hadI"
                     /locus_tag="ACGI5H_002994"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888223.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-hydroxyisocaproyl-CoA dehydratase activator
                     HadI"
                     /protein_id="HFG9698690.1"
                     /translation="MYTMGLDIGSTASKGVILKNGEDIVASETISSGTGTTGPSRVLE
                     KLYGKTGLAREDIKKVVVTGYGRMNYSDADKQISELSCHARGVNFIIPETRTIIDIGG
                     QDAKVLKLDNNGRLLNFLMNDKCAAGTGRFLDVMAKIIEVDVSELGSISMNSQNEVSI
                     SSTCTVFAESEVISHLSENAKIEDIVAGIHTSVAKRVSSLVKRIGVQRNVVMVGGVAR
                     NSGIVRAMAREINTEIIVPDIPQLTGALGAALYAFDEAKESQKEVKNI"
     gene            complement(12369..13568)
                     /gene="hadA"
                     /locus_tag="ACGI5H_002995"
     CDS             complement(12369..13568)
                     /gene="hadA"
                     /locus_tag="ACGI5H_002995"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427766.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="isocaprenoyl-CoA:2-hydroxyisocaproate
                     CoA-transferase HadA"
                     /protein_id="HFG9698691.1"
                     /translation="MLLEGVKVVELSSFIAAPCCAKMLGDWGAEVIKIEPIEGDGIRV
                     MGGTFKSPASDDENPMFELENGNKKGVSINVKSKEGVEILHKLLSEADIFVTNVRVQA
                     LEKMGIAYDQIKDKYPGLIFSQILGYGEKGPLKDKPGFDYTAYFARGGVSQSVMEKGT
                     SPANTAAGFGDHYAGLALAAGSLAALHKKAQTGKGERVTVSLFHTAIYGMGTMITTAQ
                     YGNEMPLSRENPNSPLMTTYKCKDGRWIQLALIQYNKWLGKFCKVINREYILEDDRYN
                     NIDSMVNHVEDLVKIVGEAMLEKTLDEWSALLEEADLPFEKIQSCEDLLDDEQAWAND
                     FLFKKTYDSGNTGVLVNTPVMFRNEGIKEYTPAPKVGQHTVEVLKSLGYDEEKINNFK
                     DSKVVRY"
     gene            14245..15243
                     /locus_tag="ACGI5H_002996"
     CDS             14245..15243
                     /locus_tag="ACGI5H_002996"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003431407.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-2-hydroxyacid dehydrogenase"
                     /protein_id="HFG9698692.1"
                     /translation="MKILVFGARDYEEPVIKKWSEEHKDVQVDIYPENMTEENVVKAK
                     GYDGISIQQTNYIDNPYIYETLKDAGVKVIASRTAGVDMIHFDLVNENGLIVTNVPSY
                     SPNAIAELAVTQAMNLLRKTPLVKKKVCEGDYRWIAELLGTEVRSITVGVIGTGKIGA
                     TSAKLFKGLGANVIAFDQYPNSDLNDILTYKDSLEDLLKEADLITLHTPLLEGTKHMI
                     NKDTLAIMKDGAYIVNTGRGGLINTGDLIEALESGKIRAAALDTFETEGLFLNKKMNP
                     GELTDPEINKLLSMEQVIFTHHLGFFTSTAIENIVYSSLSSAVEVIKTGTATNRVN"
     gene            15605..16132
                     /locus_tag="ACGI5H_002997"
     CDS             15605..16132
                     /locus_tag="ACGI5H_002997"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417338.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR04002 family protein"
                     /protein_id="HFG9698693.1"
                     /translation="MEKMNKVTSKKTTYIVTSALFASIICLTIAYILHIPVGGNNGYV
                     HIGDAFIYLAATILPTNYAIAASAIGAGLADLSTGAAIWVIPTIIIKPILVLFFTSKS
                     DKIINKRNIVASVVAGIVGLVLYMFAEGIIIGSFTSAFVMSLLGLLQPIGSFIVFIIL
                     GMALDKLDFKKRYFN"
     gene            16159..16755
                     /locus_tag="ACGI5H_002998"
     CDS             16159..16755
                     /locus_tag="ACGI5H_002998"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434869.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0051539 - 4 iron, 4 sulfur cluster binding
                     [Evidence IEA];
                     GO_function: GO:1904047 - S-adenosyl-L-methionine binding
                     [Evidence IEA];
                     GO_process: GO:0046500 - S-adenosylmethionine metabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR04100 family radical SAM protein"
                     /protein_id="HFG9698694.1"
                     /translation="MNILYTIENSIYVNITNTCPCSCVFCIRNEKDEVANSGSLWLEH
                     EPSVDEVKEAFNKYNLDDYDEIVFCGYGEPLMRINELIEIAKFIKEKSSIKIRINTNG
                     LSDLIHNKKTAILLKNVIDAVSISLNAPNKEAYNRVTQPKFGEKSFDYMLDFARDCKK
                     YIKEVAFSVVDEISPEEIEESKQLAKKLDIPLRVRHKN"
     gene            complement(16820..18403)
                     /gene="asnB"
                     /locus_tag="ACGI5H_002999"
     CDS             complement(16820..18403)
                     /gene="asnB"
                     /locus_tag="ACGI5H_002999"
                     /EC_number="6.3.5.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417334.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004066 - asparagine synthase
                     (glutamine-hydrolyzing) activity [Evidence IEA];
                     GO_process: GO:0006529 - asparagine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="asparagine synthase (glutamine-hydrolyzing)"
                     /protein_id="HFG9698695.1"
                     /translation="MINLEEKYLTRKDTYMIKILEYNGHIRNWKVLCEELGIDSSLCR
                     DERERAILVEAYKTWGYDMANHMHGMFAFALWDTVEKKLFCLRDQFGVKPFYYYETEN
                     GKLLYGSSIRKIMEQPGFVKELNEDMLQIYMSFTYVAGENTFFRGVKKLMPGHYLVYQ
                     NKTVCIGRYWKPEFHPDHSKSIEEWTDEIHTTLQKIMPEVKSENETAELFLSGGVDSS
                     YILAMSDIEKTGSCGYEEERFDESKLAQQTANILGCKNSRYIITPEEYFASVPYVMYH
                     MEQPTGDASAIVFAIGCKAAAENTNICYSGEGADEFFGGYNIYHKAECYGENLKTFYI
                     GNTNIMNEGEKRKILKKYNPDVLPIEVVKGIYEETEELDTLTNMSNVDIQIWLEGDIY
                     FNIDKMSTAVGLEVRMPLTDTRIFDIASRIPSEYKVKGKENKIAFRTAASKTLPEEIA
                     FRNKLGFIVPIRIWMADDRYNKDIRDKFNSEIADKFFNIDEINEIFNDYISGNSDNWR
                     KIWMIYTFLVWYEIYFVKC"
BASE COUNT         5864 a         3441 c         2297 g         7195 t
ORIGIN      
        1 atttctataa ttaaaacttt ttttatttcg tattcccaca ctccatatat ataactacag
       61 acacatcaaa acaccttttc aattctttat tcctaatttt attaccctct aatctaaata
      121 ttatatgtct atgaaactgt ctaaagctca agatttctag cattattttc gacgtagcaa
      181 cactacagtc tcacaatgtg gcgtatttgg gaacatatcc atacacttaa ccatcttaat
      241 ctcataacca taccccttaa aatcaaccaa atcaacaacc aaagacttag gattacaaga
      301 aatataaaca atctccttag caccaaatcc acaaatatcc ctaatagcat ccttatgaat
      361 gcctggtcta ggagggtcaa caataatcaa atcaggcttg tcctttaaat ccttaacaac
      421 cttagccaca tccccagcaa taaactcaca attagtaagt ccattcaact tagcattctc
      481 attagcagca acaacagctt cctcaactat ctcaatacca tacactttct tagcagcacc
      541 agccataacc tgtccaatag acccagtacc actatacaag tcaaatacaa ctttatcatt
      601 gtaatctcca ataaaatccc tagcaatact ataaagaacc tctgctccct tagtattggt
      661 ttggaaaaac gaaaatggtg aaatcttaaa cttaagacct aaaatttctt cttgtatata
      721 atctcttcca tacaatactc ttaactcatc acattggact gcatctgcta aaccatcatt
      781 aatagtatga agtacaccta ctaactcagc ttttaaatca atccctaaaa gcatatcttt
      841 aaactcatac atatcaaaat cttcttgaga agaagttact atattaacca taatctcatt
      901 agtatgaatc ccttttctaa ctacaagatg tctcaaatat cctttgtgat tcattgttct
      961 ataataagga agcttttttt cattgaaaaa ctctacacta gaaactaata tctttgagaa
     1021 gtcttcatca accaacatac actcctcaac agtttgtata tctatatgct ttcctttttt
     1081 atgaagacct aatgtcaaag gtccattttt tacttcatct ccaaaagtat attccatctt
     1141 atttctataa tatttgtttt ctggacttcc ttctatccct aaaaactgaa atccaaataa
     1201 atcttgcttt aaaaataaat ccataacttg tttttctttt atttctaatt gtttttcata
     1261 tggcacagac aatagtgtac atcctccaca ctctctaaag tgcttgcaag tttcttcagt
     1321 ttcaagtggt gagttctcta ataattctat catcttaact tcagctttct tacttctaac
     1381 ttttttaact ccagctctca ccttttgacc acttattcca cccttcatat ggataactct
     1441 atctccaact tggcttaaag atgtaccacc aaattccatt ttatctactt caaattctat
     1501 aacatctttt ttcttcacag acattcctcc aatttactat agtatcttta ttatctttct
     1561 tcaatcaatt ttacttcttc atctgttaac tctctatact cacctaactc taaactttca
     1621 tccaatttta aattgcccat agacaatctt tttaagtata ctactttttt gcctacgctt
     1681 tcaaacattc tttttacttg gtgaaactta ccttcatgta ttgtaagctc tatttctgat
     1741 tcatcatcac tttttaatat atttaactgt gatggcatag ttttatatcc gtcatcaagc
     1801 actacacctt ctaaaaaagc ttctacatct tcttcagtaa ctactccatc aatttttgca
     1861 taataagtct taggcacatg cttcttagga gataaaactc tatgagaaag ctttccatca
     1921 ttagttaaaa ctaataatcc ctctgtgtct ttatctaacc ttccaacagg aaatggttca
     1981 aaagctaagt atgataaatc aattaaatct aatactgttg ggtcatattt atctgtagtt
     2041 gctgatatat atccatcagg tttattcatc atcaaatata tatattctct atatataact
     2101 tcttctccat taaataatat ctcatcattt tcagtgtcta cttgagttcc tggatttgaa
     2161 acttcacttc catttactac tacagaccct tgtttacaat acttctttat ttcacttcta
     2221 cttccataac ctaaatttga aagaatttta tctatacgtt gctttttagc cattaaaaat
     2281 gctctccatt ctcataatat ttttcttttt caaatactgt aaatgctaaa tctatacttt
     2341 ctacatctaa attatttctt atactatcag ttattattct tgctactata tcttgtactt
     2401 cttgtcctct atcaaaccaa gctacttcaa caaaaggata tacatctgct attttaccat
     2461 ctcttattgc aactgacttt atacattcta tttcaaagta gtctcttgga cattttacag
     2521 cttcaactaa atcatttatc attttttcac ttattttaca tatatcattt tcattaattc
     2581 ctcttatttt tatctgtggc atagtttatc tcctttattt taaattttta gtgaattatc
     2641 atccacttaa ttcctttcga taacgtttga agtggtaact tcttggtcaa ggcaactatt
     2701 gttatcagta tctccaaact aataaggtag ttcctaccct tatagttagc attatatagc
     2761 tagttttcct aaattgttta tattctttat tattttattt aatcctattg tcttctattt
     2821 aacattatac ttgtaattta tagttattac aatttactat atactttttt tgatttaacg
     2881 ttataatata agtgatgggt aaattttaaa agttaatagg aggagtttaa aatggcatta
     2941 attactacaa aagaaatgtt taaaaaagct tacgaaggtg gatttgctat aggtgcattt
     3001 aacataagtg acttagaaca attacaaggt gttttaaaag ctgctaaagc taaaaattct
     3061 tatgttatga tacaagcttc tatgtcagct gttaaatatg ctggacctca tacattagtt
     3121 gaaatggtta aggctgcttc tgatgaaata ggtgtagatg tagctcttca cttagaccat
     3181 ggtccaaata tggatgctat taaaacttgt attgatgctg gtttctcttc agttatgata
     3241 gatggttctc attttgactt tgaagaaaat gttagaataa ctaaagaagc tgttgaatat
     3301 gcacactcta aaggtgttgt tgttgaagca gaacttggtg ttctagctgg aacagaagat
     3361 gatgttactt ctgatgttca caagtatact caaccagctg aggcagttga gttcgttgaa
     3421 agaacaggtg ttgattcatt agcaatagct attggaactt ctcatggtgc tttcaaattc
     3481 aaaggagaag ctaaattaag attcgatata ctagaagaaa tccaaagcaa attaccaggt
     3541 ttcccaatag ttcttcatgg tgcatctgct gttgaccaaa acgctgttgc tacatgtaat
     3601 gaatttggtg gaaatatagc tggtgctaaa ggtgtacctg tagatatgtt aagaaaagca
     3661 tcttctatgg ctgtttgtaa aataaacatg gatactgact taagactagc tatgactgct
     3721 gctatcagaa aattcttagc tgaaaatcca aaagaatttg acccaagaaa atacattggt
     3781 gctggtagag atgctataca agctgtagtt gaaagcaaga tagatgatgt tttaggttct
     3841 gctaactcta taaactaata taacttttaa atatttataa aagaaaagag atgacttaaa
     3901 gtaattaaat ttatttttaa gccatctctt ttaagttgta taaattatgt atcttataat
     3961 attttaatta tattgtcttt ttaaactgac agctaaacgt gaatatgtcc actctttatc
     4021 tttctatgga tggtagaagg atatatacct ataacttcag cagcctttgt tattgaacca
     4081 tacttattta tagccttact tatcattatt tggtccacta ttttatatgc atcattaaga
     4141 ttcataattc catttaccac tattggtgat aaatcatctg tttcattatc aatcatatct
     4201 aaatttatca gcatgttaaa ttcatcttct ccaattacat ttttagctga taatactaca
     4261 aatctttcaa tgatgttttt taattctctt atgtttcctg gccaagaata ttcttctaat
     4321 aactcaataa ctttaggcga aacttctact tctctattgt acttttcatt gtaaagtttt
     4381 aagaaataat ttactaatgg tactatatcc tcttttcttt ctctaagagg aggtattttt
     4441 actggaataa cacttaatct atagtacaaa tcttgtctaa atttaaggtt atttctaagg
     4501 tcttcatgag aaatattagt agcacttata tatctaacat ctatttttat aggcttacta
     4561 ccacctattc tagtaatagt attttcttgt ataaccctaa gtaatttttt ttgcatctgc
     4621 attggtaact cacctatctc atccaagaaa atagttccac cattcgcctc ttcaaaaagt
     4681 ccctttttac cttttttctt agctccagta aaagaacctt cttcatatcc aaaaaactct
     4741 gactctaata attcatttgg tatagctcca cagtttatag ctataaaagg tttgtctctc
     4801 cttgaactat acttatatat tgttcttgct attatttctt ttcctacacc tgattctcca
     4861 tttataaata tagaagaatc tgaggctgca gctctcttaa caactttttt tatattgtcc
     4921 ataatcttac tttgacttat atactctgtg tcttctgata tatcactata ttttatctga
     4981 gattcaagct taataaccct tgaaatatct ctccctgtta gtactcctcc tgtaagcttt
     5041 cccttagaat cccatcttgg aactgccgta tatgcaataa gcttcccatc tgggtaaacg
     5101 atatttctat aaatcttttt cttcacttta agcatgttta atattattgg ttcttcaact
     5161 aatccttgtc tcacaaggtc tgttatattt ctaccaagta cctcagttct tttaaaaggt
     5221 aatatctcat cactgacagt gttcatcttt tcaattaccc catctttgtt aaacacaaca
     5281 acaacttcat ctatatgctc tattatatct tcaattactt tatcagatat tagagacttc
     5341 tcaaataaat aaactatatt attttcatta ttattatctt tcatattgta tatatgtgca
     5401 gtcatcctta actctctgaa agctattttc tttttactat ctgtcagtat ttctgttttg
     5461 tcaaaatttg aatctaattc atttatattt ctaggctttt ttatatctag aaaactaaaa
     5521 atactatcta ttagatgatt acagtatatt atttcgcctg attctttaca taaaatggct
     5581 ggattttcta catgttctat aagccctatt aaattattat ccattaatat tcgcaccttt
     5641 cattaagtaa tttattgaac tacatacaaa atttattgtt tgcttacaat aaataccatc
     5701 agcacatata atcaactcct tataatattc gtcttttcaa gtagtttatt tcattaaaac
     5761 gtaactaaga tataatttta atgattatag tttgttaaaa atttcatttt gcttttaatt
     5821 gtattttatc acatatttag taattatttg tctatttaat acaatttaat taaatttaag
     5881 atttatttaa aaaaacaaag ataatcctta cagaatataa ctcacaattt gtaagcaata
     5941 tacatataag gattatccag attatcttgt attataaaat tttattcaaa cagacttttt
     6001 aataactgac aaatacacac tagcaataac ttatcaaagg gttaataatt atgttactaa
     6061 ctaataagac ttattcaatc agtaatattt atatagtttg tatctattaa gcttttatag
     6121 cttctaataa atcatcaacg ctatctaatt tttctataag cattggaact atttcatgta
     6181 agtctccaac tactccatag tcagcgattt ctaaaattgg agctgctggg tttttgttta
     6241 tagcaattat gaaatctgat gattgcatac ctgctaaatg ttgtattgct cctgatatac
     6301 cacaagctat atataggttt ggtttaacag tagttcctgt ttgacctact tggtgagaat
     6361 ggtctatcca tccagcatca acagccgcac gagaagaacc aactactcca cctaatttgt
     6421 cagctaattt cttaagcatt tcaaatcctt ctggtccacc taatcctaga ccacctgata
     6481 ctataacatt tgcatctgta agagatacta aatctttctt agttttaact gtttctaaaa
     6541 cagtagttct tatatcatct tgagttattt tgtagtctaa tgctataact tcaccagttc
     6601 ttgtttcgtc tttttcagct ttatccataa caccaggtct aactgtagac atttgaggtc
     6661 tatggtttgg acaaatgatt gtagccatta tgtttccacc aaatgctgga cgagtttgtt
     6721 ttattttctt atcttctggg tctatttcta acttagtaca gtcagctgtt aatccagttc
     6781 caactcttga agctattcta ggtgctaagt ctctacctat atgagttgct ccgaaaagca
     6841 ttatttctgg ttttatttca tctattgcat cttttattac ttttgtatat gcatcagttg
     6901 tatatttttc taaaagagca tcatctgcaa cataaacttt gtcagctcca aaagtgatta
     6961 attctttagc taatccatca acatcttttc ctaataatat tgcacaaagt tctgcatcta
     7021 cttctttagc taattttctt ccttctccta ataattctat aactactgga gctatttttc
     7081 cttctctttg ttctgcaaat atccatacgt ttttataaga acttaaatct tttatatcat
     7141 tcatagtttg tactcctcca acttatataa tgtgcttttg ttttagaccg attattattt
     7201 tactagctat ttcatcagct ttaccttcta agatttctcc ttttcctctt ggttcaggag
     7261 taaatgatct aaatacttta gttggtgatg cttttaaacc aacttcttct ttatttacat
     7321 ctaaatcatc aattgtccaa acttttacat catgtttata tgcttttact attttatcaa
     7381 cagacatgta tctaggtgta tttaactctt ttactgctgt taaaagtaca ggtgtactta
     7441 cttttattaa ttcgtatcca tcttctaatt gtctttgaac tattatatct tttccttcta
     7501 ttttgaaatc ttgtacatat gtaacttgag gaatgtctaa tttctctgca atttgtggtc
     7561 caacttgtgc agtatctcca tctattgctt gtcttcctgc aaatattatg tcatagtcac
     7621 ctactttaga tattcccgct gcaatagtat ttgatgtagc ccaagtatca gctcctccaa
     7681 atgctctatc acttaataat attgcatcat cagcacccat agctaaacac tctcttagca
     7741 taaagtctgc ttgaggaggt cccattgtta taactgttat agttacatca tcatgctcat
     7801 ctttaatttt taaagcttcc tctaatgcat ttgcatcatc tgggtttaat atacttggaa
     7861 ctccatctct tataagagta cctgtttctt tatttattct tacttcgtta gtatctggaa
     7921 cttgttttac gcaaactaat attttcaaag tctatacctc caatttcatt agattattta
     7981 ttattttaat acgtttgatg aaattaccat tttttgaact tctgatgttc cttcgtatat
     8041 tgatacgatt ctagcatctc tgtacattct ttcgatttca taatctttta taaatccata
     8101 tccaccgtga agttgtaatg ctttataagc aacttcattt gcaatttctg atgcatagta
     8161 tttagccata gcagattctt gagcaactct cattcctgca tctctctttt gtgctgcatc
     8221 ataaactaat cctctagctg cacaaacttt tgtttccatg tcagctatag taaattgagt
     8281 attttggaat ttagctatag gcttaccaaa ttgaactctt tgttttgtat atttaacagc
     8341 ttcatctaaa gcaccttgag ctattcctag agctaaggca gcaacaccta ttctaccaac
     8401 ttctagagta cccattgcta tcttaaatcc ttgaccttct tttccaagta agttttcttt
     8461 tggaacttta acgttttcaa atattaagtc agaagtttca gttcctctta tacccatctt
     8521 atcttcatga gctcctgttg agaaaccatc ccatttactt tctactataa acgctgatgt
     8581 tcctctaagt cctttacttc tatctgtaac tgctattact atagctacat cacagaatgg
     8641 tccattagtt atgaaagttt ttctaccatt taatatatag tggtctccaa ctaattctgc
     8701 tgttgtttgt tgtccacctg catcagaacc agctcctggc tcagttaaac caaatgctcc
     8761 tattaattca cctgttgcta taccttttaa gtatttttgt ttttgctctt cagtaccatt
     8821 gtaaagtatt ggtaatgaag caagagaaga accagctgta acaaaagtag ctgttgaagc
     8881 acatcttcta gctatttctt ccattactat agcgtaagaa acatatcctg ctcccccacc
     8941 accatattct tctgggatat tactgcttat aaattttgca tcagctaatt ttttgattaa
     9001 ttccttaggc attacacctg ttttatccat ttctgctggt aaagtatcta attctttact
     9061 aacaaaatct cttactgctt ttcttaaaag ttcttgttct ttgttatata acatagcttc
     9121 ctccaatttt catattttat agtaaattta ttttaatgaa cttacgctaa actcatcatc
     9181 tcagcaaaag tttgaatacg agttctggct tgttcattat tctgagtttg ttggtcgatt
     9241 tcaacatata aagtaggtat tccactatct tctatatctt ttctaactaa aggataatcg
     9301 tattcttctg ggtcacagaa tttcatcata cagaagataa caccatctat atctttcttt
     9361 ttaacttcat ctactataag tgacccacgt tttttcttag ggtcataagc taatgaacat
     9421 ccttctatgt ttgaccattg tcttgctaat ctttctaacg catcatcacc tgctggtaca
     9481 tctgttctga attgtcttgt ttcttgtgct aagtcgtcag ctacaactga tatattgttg
     9541 tcttctaaaa tgtctaatat atctttagaa tcagctaata tacctgttaa taaaactttc
     9601 tttccagaac agacttcttc tggcatagca tttaattttg ctattaaatc tttcactagc
     9661 tcagtatgtt cttcttttct cataaagaac ccactcttaa ttactaagct tcttattgat
     9721 ggttttatag tattagaatg tttataagct acttcaacaa agtctctcat agtttttcta
     9781 tgttcattgt aaacttctat actttcatga atttttgctt cttctatttc atatccacaa
     9841 atttcttcaa gttctctttt tacgcctttg tactcactga ttaagtattt tacaccagct
     9901 tcaagttttc tattttgtgg gtgtactaat gatatatatt ttatatgagg tactgctgat
     9961 ttccagtttt gtcctaaaca aattagtgta tcacacatac ctggtataat aactccagat
    10021 aattcatcat aagcaccttt taatccatat tctaaacatg attgcattat tgaacatgca
    10081 aatgcaggga aatattgttt agctaaatct aattctgttt gccctcccca tataccaact
    10141 ggaagcattc cagctgcatg tataatttct tctgggcaat aaactgggaa acaacctata
    10201 gcttttttac cagtttcact tttatatttt tttacagccg catttggatt ttcaactact
    10261 tctttcattt tagataaaat agcttccatt atatctcacc tctattaagt ttttttcttt
    10321 cttccattac ttcaactaaa ccttgaattc ttgtttcaaa ttgagcatta gtgaaagctc
    10381 tagggtctgc ttggtcacca tcaaatccag catatggtaa tccagtttct tcagctgctc
    10441 ttctttgcat ttcatattgt attaaactca taagtttaca gcttctgttc atatgataga
    10501 atgctccatc acatttaccc tctactaaag aatcaactct atattttgtc atacggtcta
    10561 ggtttacatt gttaaacata gtactatatg ctactgccat tccatctaaa tcattaactt
    10621 catattgtaa tgcccaagca tgtgggtaaa cactacctgt catgttaact ccaaatttag
    10681 ctaatgtttt catcttgtat cctatatatg gccaacaagg tataccttcc atcattattc
    10741 tgtatttttc ttcccctctg aaagaagatt taccagtttt catgttgtcc tctaattctt
    10801 ctataagtaa cttaaatgct tctgtagttt cttttttacc tctagcacaa actattacag
    10861 ccatgtaagt aaataagtca aatccattca ttggagaagg agaagaatct gctggtaaac
    10921 tcatagaata cttccatagt cttccgtttt cagctgatat tttcattact tcttcaaact
    10981 tcttagggtc aaatttcttt cctgatataa tttctagttg ttttatagct tcttcaaatt
    11041 gagctttaat ataatctatt cttgattgag taacttcgtc ttcattattg aaagttgtat
    11101 caatcattat taaaggtata tctaattctc ttgaaatatt ttcataccat tttataactt
    11161 ggttacatat attgttacag caaagtagga aatctggagc tggcatatcc aaagcttcac
    11221 atccaccatt ttctaaaaga ccaaaatttg ttcttgcata tgcacatagg tcaatagaat
    11281 atcctttaga ttcagctatt tcacataatt ctaaagaacc ttttttagct gctactccag
    11341 ctgcttggtt ttctggatat aatacgttta agtcaaatac ttctgctaac tcttgaggaa
    11401 atactgatgt tgaccaacct acaggtcttc cttcttcttt agctttaaat gcatttgcat
    11461 attgttcagc taataaatca ttaattacta ctctagcttc ttttttttca gacattttca
    11521 tccctctttt tatatatttt tcacttcttt ttgtgattct tttgcttcat caaaagcata
    11581 taacgctgct cctaaagcac cagttaattg aggtatatca ggtacaataa tttctgtgtt
    11641 gatttctctt gccatagctc ttacaatacc actatttcta gcaactccac caaccataac
    11701 tacatttctt tgtactccta ttctttttac taggctagaa actctctttg ctactgaagt
    11761 atgaatacct gccactatat cttcaatttt tgcattttca gataaatgtg atataacctc
    11821 agactctgca aatactgtac atgtactgct tattgatact tcattttgag aattcataga
    11881 tatacttccg agttcagata catcaacctc tattattttt gccattacat ctaaaaatct
    11941 tcctgtacct gcagcacatt tgtcattcat aagaaagttt aatagtcttc cattattatc
    12001 taattttaat acctttgcat cttgaccacc tatgtcaata atggttcttg tctctggaat
    12061 tatgaaattt acccctctag catgacagct taattcactt atttgcttat cagcatctga
    12121 atagttcatt cttccatatc ctgtaactac aactttttta atatcttctc ttgcaagacc
    12181 tgtcttgcca tataattttt ctaaaactct tgatggtcca gtagtcccag taccagagga
    12241 tattgtttca gaagctacaa tatcttcccc attctttaag attactccct ttgatgcagt
    12301 tgaacctata tctaatccca ttgtgtacat ctttagcatt ctccttttaa aaaatctaga
    12361 attactaatt aatatcttac aactttacta tctttaaagt tatttatttt ctcttcatcg
    12421 tagcctaaag attttaatac ttctacagta tgttgaccta cttttggtgc tggtgtatat
    12481 tctttaattc cttcatttct aaacataact ggagtattaa ctaagacacc tgtatttccg
    12541 ctatcgtatg ttttcttaaa taagaagtca tttgcccaag cttgttcgtc atctaataaa
    12601 tcttcacagc tttgaatttt ttcaaatggt aagtctgctt cttctaataa agctgaccac
    12661 tcgtctaatg ttttttctaa catagcttct ccaactatct taactaaatc ttcaacatga
    12721 ttaaccattg aatctatgtt attatatcta tcatcttcta atatatattc tctatttata
    12781 accttacaga atttgcctaa ccacttgttg tattgtatta aagctaattg aatccatctt
    12841 ccatctttac atttatatgt agtcattaat gggctgtttg gattttctct tgataaaggc
    12901 atttcatttc cgtattgtgc tgttgttatc attgttccca ttccatatat agctgtatgg
    12961 aaaagactta ctgttactct ctcaccttta ccagtttgag cttttttatg taatgctgct
    13021 aaacttcctg ctgctagtgc tagacctgca tagtggtcac caaatcctgc tgctgtattt
    13081 gctggagatg ttcctttttc cataacagat tggctaactc ctcctcttgc gaagtatgca
    13141 gtatagtcaa atcctggttt atcttttaaa ggtccttttt caccatatcc taatatttga
    13201 gagaatatta atcctggata cttatctttt atttggtcat aagctatacc cattttttct
    13261 aatgcttgaa ctctaacatt agttacaaat atgtctgctt ctgataataa tttatgtaat
    13321 atttctactc cttcttttga ttttacatta atacttacac cctttttatt tccattttct
    13381 aattcaaaca tagggttttc atcatctgat gctggagatt taaatgttcc acccataact
    13441 cttattccat caccttctat aggttcaatc ttaataacct ctgcacccca gtcacctaac
    13501 atttttgcac aacatggtgc tgcgatgaaa cttgaaagtt ctactacttt aactccttct
    13561 aaaagcataa cgttttcctc cttaatagta tcaattataa aatttcgatt aaatcactca
    13621 taaaatactt ttttctgata ttaactgtct gatgtcaaag ttcctaatct tatctaaaat
    13681 aacttaaaaa ttattaaaat tattttttat tgttttattg tcttacacct atattgttaa
    13741 gcatttatcg tgccaacttt atatttaatc aaaatatcgc ttgatttgaa tgttttttaa
    13801 caatatgcaa ttgaataatc tttttcatat cgtggcatct tgccactatc cattgcattt
    13861 tgctattctt tctatgctta taaaagtttt ttttatatat ttttttatga aaaagcttga
    13921 catttcaaaa aaagttttca ttgctaaact caaaaacaca tgttatcatt gtaattaatc
    13981 agcaagttag ttaactaatt tcaaacttag ataatttttt aataatattt aatctaaaaa
    14041 ataacaattt ctttgataaa ttttagagta attattacat taaataaaaa attactaaat
    14101 atcaaaataa cacagggaaa acaatttcaa aactaaattt ttaaccttaa aaattttgta
    14161 taaaaaatat aaccttatat gctacatatt atttctaaat gaaaaattac cataataatt
    14221 taataattac aggagggtat tgatatgaaa atactagtat ttggagcacg cgattatgaa
    14281 gaaccagtaa taaaaaaatg gtctgaagaa cataaggatg ttcaagtgga tatttatcct
    14341 gaaaacatga ctgaagaaaa tgtagttaaa gctaaagggt atgatggtat atctatacaa
    14401 caaactaact atatagataa tccttatatt tatgaaactt taaaagatgc tggggttaaa
    14461 gttatagctt caagaactgc aggggttgac atgatacatt ttgatttagt taatgaaaat
    14521 ggacttatcg ttacaaacgt tccttcttat tcacctaatg caatagctga attagctgtt
    14581 actcaagcta tgaacctttt aagaaagact cctctagtaa agaaaaaagt ctgtgaaggt
    14641 gattaccgtt ggatagctga acttcttgga acagaagtta gatctattac agttggtgtt
    14701 ataggtacag gaaaaatagg tgctacttct gcaaaattat tcaaaggcct aggagctaat
    14761 gtaattgcat ttgaccaata tccaaatagt gatttaaatg atatattaac ttacaaagat
    14821 tctttagaag accttctaaa agaagctgac cttataacat tacatactcc tttacttgaa
    14881 ggaacaaaac atatgataaa taaagatact ctagctataa tgaaggatgg agcttacata
    14941 gtaaatactg gccgtggtgg tttaattaat acaggggatt taatagaagc actagagtca
    15001 ggaaaaatta gagctgctgc ccttgataca tttgaaactg aaggattgtt cttaaacaaa
    15061 aaaatgaatc ctggagaatt aactgaccca gaaataaata aacttctttc tatggaacaa
    15121 gttatattca ctcatcacct tggtttcttc actagtacag cgattgaaaa tatagtttat
    15181 tctagtttaa gtagtgctgt agaagttata aaaacaggaa ctgctactaa tagagtaaat
    15241 tagtatttta taaatatatt ttttcattaa ttagctatta tctaacaaaa tagcctttaa
    15301 tttcccaaat ataagagagt cagctcagta tatattgagt agactctctt atattatttt
    15361 ttatattaaa cttgtactct tcttattcat accaaattaa atttatatta acttattcta
    15421 actactccta ctctatacat tttacctatt tttacttttc taattatata catttgaatg
    15481 ggtacaatct gtattttaca aaaaaaacac ctaacaaact atgaaaattg tatgattaat
    15541 attaatatat ttataagaaa acataacaat tatgttagct ctggattttt agggagggag
    15601 tatattggaa aaaatgaata aagttacttc taaaaaaact acctatattg ttacttcagc
    15661 attatttgca tccataatat gcctgacaat agcatatata ttacatattc cagttggtgg
    15721 aaacaatgga tatgttcata taggagatgc ttttatttat ctagctgcaa ctattttgcc
    15781 aacaaactat gctatagctg cttctgcaat tggtgctggt ctagctgatt tatctacagg
    15841 tgctgctatc tgggtaatac caactataat cataaaacca atacttgtat tatttttcac
    15901 ttctaaaagt gacaagataa taaataagag aaatatagtt gcttcggttg tagcaggtat
    15961 agtaggatta gttttataca tgtttgctga aggtataatt attggaagtt ttacaagtgc
    16021 atttgtaatg agcttacttg gcttattaca gccaatagga agttttattg tttttataat
    16081 cttaggtatg gcacttgata aacttgattt taaaaaacgt tattttaatt aagaatttaa
    16141 atttatggag ggaaaattat gaatatctta tatacaattg aaaatagtat ctatgtaaat
    16201 ataactaata catgtccatg tagttgtgtt ttttgtataa gaaacgaaaa agatgaagtt
    16261 gcaaatagtg gtagtttatg gttggagcat gagccaagtg tagatgaagt aaaagaagcc
    16321 ttcaataaat acaatttaga cgactatgat gaaatcgtat tttgtggata tggcgaacca
    16381 ttaatgagaa taaatgaatt gatagagata gcaaagttta taaaagaaaa aagtagcata
    16441 aagataagaa taaatacaaa tggtctaagt gatttaatac ataacaaaaa aacagctatt
    16501 ctgttaaaaa atgttataga tgcagtatca ataagtctta atgccccaaa taaagaagct
    16561 tataatagag ttactcaacc aaagtttgga gaaaaatcat ttgattatat gttagatttt
    16621 gcaagagatt gcaaaaaata tataaaagaa gtagcttttt cagtagtaga tgaaatatct
    16681 ccagaagaaa tagaagaatc taaacaactg gcaaaaaaac ttgatatacc attaagagtt
    16741 agacataaga attagcaagt aaaattataa aacattaaga atcacctgaa tggtatttca
    16801 ggtgattctt cctcttgtat taacatttta caaaatagat ttcataccac actaggaatg
    16861 tgtaaatcat ccaaatcttt ctccaattat cagagtttcc actaatgtag tcattaaaaa
    16921 tctcattaat ctcatctatg ttaaagaatt tatctgctat ctcactattg aatttatctc
    16981 ggatatcctt attatatcgg tcatcagcca tccatatacg aattggcaca ataaatccta
    17041 atttatttct aaaagcaatc tcttctggta atgtttttga tgcagctgta cgaaaggcaa
    17101 ttttattctc ttttcctttc actttatatt ctgatggtat tctggatgca atatcaaata
    17161 ttcttgtatc tgtaagaggc attctgactt ccaatcctac tgcagtactc attttatcta
    17221 tattaaaata aatatctcct tccaaccata tttgaatatc tacatttgac atgttagtaa
    17281 gtgtatctag ttcttctgtt tcttcataaa ttccttttac cacttcaata ggaagcacat
    17341 caggattgta tttcttaaga atttttcttt tctcaccctc attcataatg tttgtatttc
    17401 caatataaaa tgtcttcaaa ttctctccat aacactctgc cttatggtat atattatatc
    17461 caccaaaaaa ctcatctgct ccttctccag agtaacagat atttgtgttt tcagctgctg
    17521 ccttgcatcc aatagcaaaa acgatagcag atgcatctcc agttggttgc tccatatggt
    17581 acattacata aggtactgac gcaaaatact cttcaggtgt aattatatat ctcgaatttt
    17641 tacacccaag aatattagct gtctgttgtg ctaattttga ttcatcaaaa cgctcttcct
    17701 cataaccaca tgaacctgtt ttttctatat ctgacattgc caatatataa gatgaatcaa
    17761 cacctcctga taggaataac tctgcagttt cattctctga ttttacctct ggcataattt
    17821 tctgaagtgt tgtatgaatt tcatccgtcc attcctcaat agacttgctg tggtcaggat
    17881 gaaattcagg tttccaataa cgaccaatac atactgtttt attctgatag acaaggtaat
    17941 gtcctggcat aagcttcttt actccacgga agaatgtatt ttcacctgct acatatgtga
    18001 aagacatata aatctgtaac atgtcttcat ttaactcttt cacaaatcct ggttgctcca
    18061 taatcttacg aatagatgaa ccatagagaa gcttcccatt ttcagtctca taataataga
    18121 aaggttttac cccaaactgg tctcttaggc agaagagttt cttttccaca gtatcccata
    18181 atgcaaaagc aaacattcca tgcatgtgat ttgccatatc atatccccat gtcttatatg
    18241 cttccactaa aattgctcgt tcacgctcat ctctacataa tgaagaatcg attccaagtt
    18301 cttcacaaag aactttccag tttcgaatat gcccattgta ttctagaatt tttatcatat
    18361 atgtgtcttt tcgtgttaaa tacttttctt ctaaatttat catatgtgta tcctttcgta
    18421 ttaaaacatt taacttctaa atttattaaa tgtttatata tatttattca cttataatca
    18481 ctgaaaaatc gacttttttc aaagtaaatt ctttttgaat tagtactaat ctgctcttta
    18541 ttaatggcat aaatatgatt atcaagtatt atcagtgtta taacattgaa ttttttattc
    18601 ttcataaata ttgccccctt tatattacca actaaatata atatatctta tgttacttac
    18661 atattcttta agaaattctg aagattttat aaagtttttt gtattataat taattaaaaa
    18721 taaaattcta gttataaaac atattttcca ttaaacaaaa aaatagttaa aataaattca
    18781 taaccacata aacttat
//
LOCUS       DAYAOO010000080        18548 bp    DNA     linear   BCT 12-OCT-2024
DEFINITION  TPA_asm: Clostridioides difficile isolate ST8-SSI-h139-18
            SAMN40601845-rid21577343.denovo.080, whole genome shotgun sequence.
ACCESSION   DAYAOO010000080 DAYAOO010000000
VERSION     DAYAOO010000080.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN40601845
            Sequence Read Archive: SRR28438827
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 18548)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 18548)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-MAY-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-MAY-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002157583.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002157583.1
            Genome Coverage       :: 163x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/11/2024 16:19:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 4,038
            CDSs (total)                      :: 3,963
            Genes (coding)                    :: 3,930
            CDSs (with protein)               :: 3,930
            Genes (RNA)                       :: 75
            rRNAs                             :: 6, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 60
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 33
            CDSs (without protein)            :: 33
            Pseudo Genes (ambiguous residues) :: 0 of 33
            Pseudo Genes (frameshifted)       :: 7 of 33
            Pseudo Genes (incomplete)         :: 25 of 33
            Pseudo Genes (internal stop)      :: 11 of 33
            Pseudo Genes (multiple problems)  :: 8 of 33
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..18548
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN40601845-rid21577343.denovo.080"
                     /isolate="ST8-SSI-h139-18"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Denmark"
                     /collection_date="2018"
                     /collected_by="Statens Serum Institute"
     gene            167..1327
                     /locus_tag="ACGI5H_003000"
     CDS             167..1327
                     /locus_tag="ACGI5H_003000"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430586.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF819 family protein"
                     /protein_id="HFG9698696.1"
                     /translation="MIETGFVYCSFLVVFVGVIFFMVDKLKWKVFDVINPMLLIYLGS
                     AILGSFGLFAQNEDVGTYQNIITVNFLPLMLVFLLIQCDLRKILKMGPKMLLSFFCAT
                     FTFMLGFVIAFIIFKNSMGADSWKILGAASGSWIGGSSNMIAAANALGVAEEGLSYAI
                     LMGSIGYTVWMSVCLMSVKFGPKFNKWTKCDTSFIDEVTSKLEKENKDNTAPTFVELM
                     ILLSVGFGVASFAQIVSKILPTSGILNETMWVVLVASTVSILLGMTKISKLKGSTLVG
                     NVFMYLLLAATGSKANFFGLSEAPVYIMFGLVVVLVHAISFIGLAKLFKLDLFTCEVG
                     SIANIGGVTTAPMIAGVHNPVLIPVGVLMGLLGNIIGTYCALMVTQILHMLA"
     gene            1669..1830
                     /locus_tag="ACGI5H_003001"
     CDS             1669..1830
                     /locus_tag="ACGI5H_003001"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9698697.1"
                     /translation="MIIPSRRIQDITLTNLKNGEVTLIELDEIYKKMGFLFVVSEGKL
                     KKIKKENHH"
     gene            2023..2652
                     /locus_tag="ACGI5H_003002"
     CDS             2023..2652
                     /locus_tag="ACGI5H_003002"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424558.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003824 - catalytic activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease/exonuclease/phosphatase family
                     protein"
                     /protein_id="HFG9698698.1"
                     /translation="MKIVTYNIHKGMDSNNRLTLTKMGLYLKQLDCDVICLQEVLYPQ
                     FLALKAVLNMDGVFATNVKKVNMIYGICTFTTSKMLNSNHFFLTSKKEQRGALCITID
                     AYGRIINVINTHLGLDRQERAKQLDEIIDYRNRLVGIVILCGDFNEKNVFLSMFNDMA
                     ISLNKSYLPTFEKSNSRIDYIFVNKNTELKGYTVEKIYLSDHYPVIGYI"
     gene            2891..4150
                     /locus_tag="ACGI5H_003003"
     CDS             2891..4150
                     /locus_tag="ACGI5H_003003"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861472.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VanW family protein"
                     /protein_id="HFG9698699.1"
                     /translation="MGRRTTRVSRLGKEKKRSVLIVLAALVLIMGGFTYFFNSKFLYN
                     GKIAKNVYIEGVNVSDMTKAEALKAITDKYTPEDLNLAYDGKKYTISPKDIDLKYDTE
                     DVVKDAYESTKKGSYFQNLKKYIDIRVNKANMKIKAEYDEAKLSSKVSSIADSINVKM
                     KNASISVGSGGLSYTDSVVGREFDLAANKESIYNMIKNKEHKTLELKVNLQKPDITTE
                     QVKTVNSVIGQYSTTYSQAVEGRSYNVGLSARKTSDVLLMPGEEFSYNKLTGPSNKAN
                     GYKDAPVIVYGKLEQSAGGGVCQTSSTVYNAALLSGMEITQVTNHSSASTYVPKGRDA
                     TVSDGGLNLKFKNPYKHPVYIKNYAGGGSVSSVIYGNSGDKPNISIEVKQTGQNKYST
                     YRIFKDSSGKVIKKEHISNSSYKELKK"
     gene            4421..5404
                     /locus_tag="ACGI5H_003004"
     CDS             4421..5404
                     /locus_tag="ACGI5H_003004"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424555.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004672 - protein kinase activity
                     [Evidence IEA];
                     GO_process: GO:0006468 - protein phosphorylation [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="protein kinase"
                     /protein_id="HFG9698700.1"
                     /translation="MTWLNFIGNRYEVVNSDDVLEINKIYKARDVFYRKNVLIKVIKH
                     NNYICEDFVSNLIDESTALDEINSPYILKIIDVGIHCTEETTLYYVVSEDFNGIGLDE
                     LILGNYLHLEAIVNIMIQVLKALEMIHRNHSYHGSLKSSSIIVDTEYNIKICDFGITK
                     ANNGVNTRSYGNRRYLCPHQLCINYTDKESDFFATGLILFESIFKKLPFGESNSEEKM
                     LQSIDKGLDWNSIKAINGNTELINVIKRLLGRNNKYTRANDIIIDLSKVMYEKAYIEV
                     EDEKEEEQKQDKVIQVKKEYKSKMRKKLHKKLVVAGLAIVMISMIIISSII"
     gene            5650..6717
                     /locus_tag="ACGI5H_003005"
     CDS             5650..6717
                     /locus_tag="ACGI5H_003005"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890294.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008452 - RNA ligase activity [Evidence
                     IEA];
                     GO_process: GO:0006396 - RNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="RNA ligase RtcB family protein"
                     /protein_id="HFG9698701.1"
                     /translation="MSNIKIIASNKCWIEDIARKQLEDISKLNGILRVVGLPDLHAGK
                     IPVGLAVETKNIIYPHIIGNDIGCGMTLFKTGVLKKKFKKDKWIKSLSKIKDLSDIEI
                     KNTYKEECPILNLGTIGSGNHFAEIQCISEIYNKEQFEQLKFSSDDIMMLVHCGSRNY
                     GEDILKKFYDKDGLEVESEKAIDYIKKHDNALMWAERNREAISKKIMQSIGTSGDVET
                     IFSINHNFIEKREDKFIHRKGAVSSERGAVIIPGSRGSLSYIVMPTENTEISLYSLSH
                     GAGRKWSRSVCKSRLKSKYSKDTIKQTKFKSQIICNDVNLLFQEAPEAYKNIEQIIES
                     LIEYELIQVVATMKPLITYKG"
     gene            7251..9161
                     /locus_tag="ACGI5H_003006"
     CDS             7251..9161
                     /locus_tag="ACGI5H_003006"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430591.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease MutS2"
                     /protein_id="HFG9698702.1"
                     /translation="MNSNTFERLQLNEVKDLIKIHCVSSLGKNLIDKLTPSGNIGVVR
                     RKLAENKEARKIIENSNHIPLEGLFNVGSTIDKIEKGMIIEPVELVNIEDFLRGCRKM
                     KAFMLEKEFYSPTLSSYALNITECKSIEDEINYCIKSNKVDSNASKELKKIRRNIEIT
                     EGKIKDRLNKFITSTVNKKYIQEFIISKRNDRYVIPIKSSYKNEVNGTILDTSSKGNT
                     VFIEPISVSNLSTELTMLKADETIEEYKILSYLTELIFEKISQIKLNIEILSEYDMVF
                     AKAKYSQKIKGITPKINNNGYIKIIKGKHPLLTGDAVPLDFEIGKNYRSLIITGPNAG
                     GKTVTLKTVGLLTLMVQCGFDISAKEGSEFSVFEKVFVDIGDNQSIENALSTFSSHIK
                     NIAEIMSLSNNSTLVLFDEIGSGTEPNEGAGLAISLLEEFYKMGCITIASTHYGEIKK
                     FATLHPEFENAGMMFDKETLEPLYKLTIGKSEDSNALFISKKMGIKNRVLDRAKEYVI
                     DRNYNLDLVKRSKLQSNIEDKNSSEVILNYTDYNVGDKVKLLDEDDFGIVYKPMDKFN
                     NVEVLFNDNFISVNIKRLQLSIKASELYPEGYDLDVLFTSFKERKLEKDIQRGSKKAL
                     KKIQKEIRENRK"
     gene            complement(9224..9847)
                     /gene="ytaF"
                     /locus_tag="ACGI5H_003007"
     CDS             complement(9224..9847)
                     /gene="ytaF"
                     /locus_tag="ACGI5H_003007"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0003674 - molecular_function [Evidence
                     IEA];
                     GO_process: GO:0030436 - asexual sporulation [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sporulation membrane protein YtaF"
                     /protein_id="HFG9698703.1"
                     /translation="MIESILLVTSLCIDAFVTSFGYGVNKVKVPLYSNIIISVVCSAI
                     LAISLFAGTIVRDFLPQNITMLICFFILFLLGSARLIESFFKSYFKKKSIHSKNYNFN
                     MLDLKLNFNVSIEPDVLDTSKSKVLKSAEAFTLALALSLDGLAIGFGSGLVGVNYIQV
                     ILFSLISNIIAVLLGCLLGNMFVKNVNLNLSWLSGLILLVIGFMKIC"
     gene            10035..10679
                     /locus_tag="ACGI5H_003008"
     CDS             10035..10679
                     /locus_tag="ACGI5H_003008"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861468.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HFG9698704.1"
                     /translation="MEQNNKVGNFGDLLKILLDEKELSMGELSKKSGIDKSTISRIAN
                     NKQKPNINHLEKMAIHLNINLEELLKASGYEFRNSNNQIFNADSDFSNFDDILGFANL
                     INDKNFNGNIEKELSKCKLYVQTDEGKKLLFDNFNKKIDSIEKQGQFTDRLRQMYADF
                     CTDGLTIKKYLLIGSMLLYFVISTDVIPDFVFPIGFMDDLVALNIVTKLLKNDK"
     gene            10893..11951
                     /locus_tag="ACGI5H_003009"
     CDS             10893..11951
                     /locus_tag="ACGI5H_003009"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433992.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="potassium channel family protein"
                     /protein_id="HFG9698705.1"
                     /translation="MNCKWISKIDERKKCHREADSSGYCIFHKENKSDEEIQLMMDTI
                     HKEEISEFNGFVFENEFNAEEILTYNYKILDFSESIFKQKANFKKYIFKKNIIFNYTE
                     FRDKVLFNGCVFLENCDFNRSIFSKNYINDRIFEKVKFKGPDLVVNKVENFPRMDGII
                     FSMCTKFVLKNVEYGKSEYEHGKINYRIARNQATKIGEYEMIGFYYYKERIYSSKIMK
                     RSNYPTFSDYLVEKFFDQIARYTTGYGEKPWNILLVIIAIISVFALLYLFVGIESSNS
                     TLVALDINNIGDYSLSEIFKMYMDLWYFSMATFSTVGYGDMVATSLIGKALAGIEVFF
                     GVTIGAIWASVIIKRMIR"
     gene            12055..13239
                     /locus_tag="ACGI5H_003010"
     CDS             12055..13239
                     /locus_tag="ACGI5H_003010"
                     /EC_number="3.4.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890281.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008236 - serine-type peptidase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanyl-D-alanine carboxypeptidase family
                     protein"
                     /protein_id="HFG9698706.1"
                     /translation="MKNALKKIISLAMILVFIIPNYSYADDKSVDKYSKTSILIDQET
                     GRVLYSKEPDMKVPLASLSKMMTFLLAIEAIENKEVKETDKVKIDKSIASVKGSSYKL
                     KDGEEVPLIELMRGLMIVSGNDAAIAIAKHICKTKEAFVDRMNKKAKEIGMSNTHFLN
                     PNGLPIYDLSNPKKPAKENISTAKDIAILGKYMFDHYEKQVTAITDMETYTNSDRSFE
                     KSNTNALLRIIPEVDGIKTGYTGNAGYCLSFSMIVNKNDKNEKKRRVIGVVLGTNHKN
                     KRTSASLALLKYGKENFNMKKVIDKDSFIGKKYIKGMKELEVTLKAKDELYTILKDDE
                     SIKSEVKIKNIEYPVKKGDTMGIIKYYTNSGDLLGSVDIVSNNSIDNVSLKTKLKMKF
                     AN"
     gene            13446..14159
                     /gene="rpsB"
                     /locus_tag="ACGI5H_003011"
     CDS             13446..14159
                     /gene="rpsB"
                     /locus_tag="ACGI5H_003011"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424537.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0015935 - small ribosomal subunit
                     [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S2"
                     /protein_id="HFG9698707.1"
                     /translation="MSVISMKQLLEAGVHFGHQTRRWNPKMAKYIFTERNGIYIIDLQ
                     KTVKKVEEAYKFTKEVAETGKPILFVGTKKQAQDAIKDEAERCGMYFVNERWLGGMLT
                     NHKTIKTRINKLRELEKMEEEGVFNVLPKKEVIKLRAEKEKLEKYLGGIKDMPELPGA
                     MFVVDPRKENIAIQEAHRLGIPVVGIVDTNCDPEQLDFAIPGNDDAIRAVKLITGAMA
                     TAVIEGRQGAEEEVAEDQE"
     gene            14238..15149
                     /gene="tsf"
                     /locus_tag="ACGI5H_003012"
     CDS             14238..15149
                     /gene="tsf"
                     /locus_tag="ACGI5H_003012"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424535.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003746 - translation elongation factor
                     activity [Evidence IEA];
                     GO_process: GO:0006414 - translational elongation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="translation elongation factor Ts"
                     /protein_id="HFG9698708.1"
                     /translation="MANITAQMVKELRESTGAGMMDCKKALQEAEGNMEKAVDLLREK
                     GLSKAAKKAGRVAAEGLVAIEMNDDNTVASMVEVNSETDFVAKNEDFKVFVKDAACMA
                     LATDKEDIASLLGETHKEGITLQEVLNNRVAKIGEKLDFRRFAKVVTNGQVAGYIHGG
                     GKIGVLVEMETEARDAKVLELGKDVAMQVAAMNPKYVSRDEVDAEYIAHETEVLTQQA
                     LNEGKPANIVEKMVKGRLEKELKEVCLLEQTFVKNPDITVKQLVADVAKAVGSDIKVV
                     KVVRFEVGEGIQKREENFAEEVAKQLK"
     gene            15234..15938
                     /gene="pyrH"
                     /locus_tag="ACGI5H_003013"
     CDS             15234..15938
                     /gene="pyrH"
                     /locus_tag="ACGI5H_003013"
                     /EC_number="2.7.4.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0033862 - UMP kinase activity [Evidence
                     IEA];
                     GO_process: GO:0006221 - pyrimidine nucleotide
                     biosynthetic process [Evidence IEA];
                     GO_process: GO:0015949 - nucleobase-containing small
                     molecule interconversion [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="UMP kinase"
                     /protein_id="HFG9698709.1"
                     /translation="MDKPMYKRVLLKLSGEALAGERGFGINNDVVNDIAIAIKKIQEI
                     GVEVAVVVGGGNFWRGRTSEGMDRTTADYIGMLATVMNAMALQDALENIDVATRVQTA
                     IDMRQIAEPYIRRRAVRHLEKERVVIFGAGTGNPYFTTDTTAALRAAEMEAEVILLAK
                     NVDAVYDKDPKVHADAKKFTELSYMEVIQKELKVMDSTATSLCMDNKIPIKVFELTTE
                     NIIRAVKGENIGTTVK"
     gene            15964..16521
                     /gene="frr"
                     /locus_tag="ACGI5H_003014"
     CDS             15964..16521
                     /gene="frr"
                     /locus_tag="ACGI5H_003014"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430598.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008135 - translation factor activity, RNA
                     binding [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome recycling factor"
                     /protein_id="HFG9698710.1"
                     /translation="MKLEIHKQLEEKMNGTIDALKFEFGTIRAGRANAQMLDKIRVDY
                     YGTPTPINQIGAISVPEPRILMISPWDKSAMHEIEKAIANSDLGLNPSNDGEVIRLSV
                     PALTEERRKELAKKASKAAEEFKVRIRNERRDANEKIKKMEKGGELTEDELKKAQDEV
                     QKMTDKFIKEIDALLSKKEKDIMEV"
     gene            16524..16727
                     /locus_tag="ACGI5H_003015"
     CDS             16524..16727
                     /locus_tag="ACGI5H_003015"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433997.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9698711.1"
                     /translation="MKKYYNLLGLHVDEVKQYFDEQNINYTVKSIEGKKDKEKLVVPR
                     VIKISEIGDSVELIITYFSDSLV"
     gene            16756..17490
                     /locus_tag="ACGI5H_003016"
     CDS             16756..17490
                     /locus_tag="ACGI5H_003016"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424529.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016765 - transferase activity,
                     transferring alkyl or aryl (other than methyl) groups
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="isoprenyl transferase"
                     /protein_id="HFG9698712.1"
                     /translation="MNNNIIYDIDLNNIPTHIAIIMDGNGRWAKARFLPRTAGHKAGV
                     ETIRDIVKECSKLGVKHLTLYAFSTENWKRPKLEVDTLMNLLSTYLRNEIAELHQNNV
                     KVTAIGDISALPKTCIRELNSAKELTKNNTGVNLNLALNYGSRADIKNALIDIVKNCE
                     SGKIDINNIDEDIIKNYLSTKSIPDPDLVIRTSGEQRLSNFLLWEVAYSEFYFTDIHW
                     PDFKKEELQKAIYVYQRRDRRFGGLK"
     gene            17503..18282
                     /locus_tag="ACGI5H_003017"
     CDS             17503..18282
                     /locus_tag="ACGI5H_003017"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424527.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatidate cytidylyltransferase"
                     /protein_id="HFG9698713.1"
                     /translation="MLTRIIASLALVPLFLFVVYGGIPLYIAETAIVYIALHEFYKAF
                     KIKDVHPIFIIGYLFSIYLAVKNIFNLPLEYTYAVIFILFLASIIYMLMGKNNVIDVS
                     ITFLGVFYIGVFLDFIIITINGFEKGSIYVWLIFVISFMTDIFAYFSGYLLGKHKLIP
                     KVSPKKTIEGAIGGIIGSTLCCILFGYLFGIDLLQLAIIGSIGSVIAQLGDLFASSIK
                     RYVGIKDYGKIIPGHGGILDRFDSVILVAPFVYSAIKFFIR"
BASE COUNT         7622 a         1849 c         3224 g         5853 t
ORIGIN      
        1 ttaatgtgca aatctttatt aatatatgtc aatagttagg tatatatgta tttaattagc
       61 atgatataga taaaagtatt tattttaatt gtctattatc tgaaaaagtc tttacttaga
      121 aatcataaaa atcaaattaa ttaggaaaag aaagggtgtg tataatgtga ttgagactgg
      181 atttgtatat tgtagtttct tggttgtatt cgtaggtgta atttttttta tggttgataa
      241 attgaaatgg aaggtatttg atgttattaa tccaatgctt ttaatatact taggttcagc
      301 tatacttgga tcatttggtt tatttgcaca gaatgaagat gttggaacgt atcaaaacat
      361 aataacagtg aacttccttc cattaatgtt agtgtttttg ttaattcaat gtgatttaag
      421 aaaaatatta aagatggggc ctaaaatgtt attatcattt ttctgtgcta catttacatt
      481 tatgcttgga tttgttatag cattcataat ttttaaaaat tcaatgggtg cagattcatg
      541 gaaaattctt ggggcagcat ctggttcatg gataggtggc tcatcaaata tgattgcagc
      601 agctaatgct ctaggagttg cagaagaagg acttagttat gcaatactta tgggttctat
      661 aggatataca gtatggatgt ctgtttgtct aatgtctgtg aaatttggac ctaaatttaa
      721 caaatggaca aagtgcgata caagttttat agatgaggtt acatcaaaac ttgaaaaaga
      781 aaataaagat aatacagcac ctacgtttgt agaacttatg attttacttt ctgttgggtt
      841 tggagttgcg tcttttgcac aaattgtatc caagatactt ccaacttcag gtatacttaa
      901 tgaaactatg tgggtagtac ttgttgcatc tacagtatca atattattgg gtatgacaaa
      961 aatatcaaag cttaaaggga gtacactggt aggaaatgtg tttatgtatt tactccttgc
     1021 agctacaggt agtaaagcaa atttctttgg attgtcagaa gcacctgttt acataatgtt
     1081 tggattggta gtagtccttg tacatgctat ttcatttata gggcttgcta aactatttaa
     1141 acttgattta tttacttgtg aagtaggaag tatagctaat ataggaggag taactacagc
     1201 tccaatgatt gctggggttc acaatcctgt attaatacca gtaggtgtac ttatggggct
     1261 tctaggaaat attataggga cttattgtgc tcttatggta actcaaatat tacatatgtt
     1321 agcttaataa aaatatggta taaaattaat aatttaaata agaaaagtca tttcaattta
     1381 agcagaagct tttactgaaa tggctttttt gtttgacaag ataatctatt tcaagaagat
     1441 gttttgacat atttagtgta taatattgta aaatttacta aaaacgagat atatttaatt
     1501 tttatattga atcgaacgtc tgtatgatgt ataataaata tacagaacga atgtttgcag
     1561 aacgggtgtt ttttgaattt attttaataa tttatgaata tatatcagaa tgcataaata
     1621 tatttaaata taaagattaa aaagaattta aaggagtgtt gataacttat gataattcca
     1681 tcaagaagaa tacaagatat aacattaaca aatttaaaaa atggtgaagt aactttaatt
     1741 gaattggatg aaatatacaa gaagatggga tttttatttg ttgttagtga aggcaaattg
     1801 aaaaagataa aaaaggagaa tcatcattag aaatgaatga aataataaat attataatag
     1861 tttataaaac ctaacttatg tagaatataa atacttaagt taggtttttt tgtgataaag
     1921 tttataagta ctcaatttta taagataaat aatggtctta agtgaaaagt aaataagttt
     1981 aaattttagt aagtattata ttgcataaga ggtgatatta ttatgaaaat agtaacctac
     2041 aatattcata aaggtatgga ttcaaataat agattaactc taactaaaat ggggttatat
     2101 ttaaaacaat tggattgtga tgtaatttgt ttgcaagaag tattatatcc tcaattttta
     2161 gctttaaaag ctgttttaaa tatggatggt gtctttgcga caaatgtaaa aaaagtaaat
     2221 atgatatatg gtatttgtac atttacaaca tctaaaatgt taaacagtaa tcattttttc
     2281 ttaactagca aaaaagaaca acggggagct ctttgtataa ctatagatgc atatggaaga
     2341 attataaatg taataaatac tcacttggga cttgataggc aggagagagc aaaacaatta
     2401 gacgaaataa tagactatag gaacagatta gtggggatag ttattttatg tggtgatttt
     2461 aatgagaaaa atgtcttttt aagtatgttt aatgatatgg ctatttcact aaacaagtct
     2521 tacttaccaa catttgaaaa atcaaactct agaatagatt acatttttgt taataaaaat
     2581 actgaactaa aaggatacac agtagaaaaa atttacctgt cagaccatta tcctgtaata
     2641 ggttacattt aaatttcaat ataaatgaaa ttagttgtta taaaataaac aattttttgt
     2701 taagaaatag taaaagaaat ataataaaaa atatcaaaaa taaaactaat tataagacat
     2761 aaatttacaa taaagttaca tttgattaaa ttccttgttt aacaaaagct attcaaatat
     2821 aatctaaggt agttttgaaa tgggaactct attatgcaaa tttaagctag tgttaaaatg
     2881 aggtgaagtt atgggcagaa gaacaacaag agtttcaaga ttaggtaaag aaaaaaaacg
     2941 aagtgtttta attgtattgg cagctttagt tctaataatg ggtggattta cttatttttt
     3001 taacagtaaa tttctgtaca atgggaaaat cgctaaaaat gtatatatag aaggagtaaa
     3061 tgtatctgat atgactaaag cagaggcatt aaaagctata acagataagt atactccaga
     3121 agatttaaat cttgcttatg atgggaaaaa atatacaata tcaccaaaag atattgattt
     3181 aaaatatgat acagaagatg ttgtaaaaga tgcttatgaa agtacaaaaa aagggtccta
     3241 ttttcaaaac ttaaaaaaat atattgatat aagagtgaat aaggcaaata tgaagataaa
     3301 agctgaatat gatgaggcaa aacttagttc caaagtgtct tctatagcag atagtataaa
     3361 tgttaagatg aaaaatgctt ctattagtgt tggaagtggt ggactaagtt atacagactc
     3421 tgttgtaggt agagaatttg atttggcagc aaataaagag tctatatata atatgataaa
     3481 aaataaagag cataaaactt tagaacttaa agtaaatctt caaaaaccag atataacaac
     3541 tgaacaagta aaaactgtaa attctgttat aggtcaatat tcaactactt attcacaagc
     3601 tgtagagggt aggtcatata atgtaggatt atcagcaaga aaaactagtg atgtattatt
     3661 aatgccaggt gaagaatttt catacaataa acttacagga cctagtaata aagcaaatgg
     3721 ttacaaagat gcacctgtta tagtttatgg taagctagaa caatcagcag gaggaggtgt
     3781 ttgtcaaaca tcttcaacag tttataatgc ggctcttctt tcgggtatgg agataactca
     3841 agttacaaat cattcatctg catctactta tgtgcctaaa gggagagatg ctactgtgag
     3901 cgatggagga ttaaacttaa agtttaaaaa tccatataag catcctgtat atattaaaaa
     3961 ttatgcaggt ggaggaagtg tatcatcagt aatctatggt aattctggtg acaaaccaaa
     4021 tatatctata gaggtaaaac aaactggtca gaataaatat tctacatatc gaatatttaa
     4081 agattcaagt ggaaaggtca taaaaaaaga acatatatca aatagttctt ataaagaatt
     4141 aaaaaaatag ataatttttt agagaaatat ttgtaatata aaagggagtg tctcaaaatg
     4201 aactttttag tttatgagac actctttttc tgtgaaatca aatatatttt catcatttca
     4261 acaatacaaa agaagcgtat ctctattttg agacagcctt ttttgtaaaa attaacacta
     4321 ttagttcttg ttttaatatt acaatcatta atatatagaa aatattccta tatattggta
     4381 taattgtaaa tagatttagt tatataaaat gtatgaggag gtgacatggt tgaattttat
     4441 aggcaataga tatgaggtag taaattctga cgacgtttta gaaattaaca aaatctataa
     4501 agctagagat gttttttaca ggaaaaatgt gttaataaaa gttataaagc acaataatta
     4561 tatctgtgaa gattttgttt caaatttaat tgatgaaagt actgctttag atgagataaa
     4621 ctctccttat atactaaaaa taatagatgt tgggattcac tgtacagaag aaacaacatt
     4681 atattatgtt gtaagtgaag actttaatgg tatcggacta gatgaattaa ttctaggtaa
     4741 ttatcttcat ttagaagcaa ttgtaaacat aatgatacaa gttttaaaag ctttagaaat
     4801 gatacatagg aatcattcat atcatggtag tttaaaatcg agtagtataa tagtagatac
     4861 agaatacaat ataaaaattt gtgattttgg aattacaaaa gcaaataatg gggttaatac
     4921 aagaagctat ggaaacagga gatatttatg cccacatcaa ctatgtataa attatactga
     4981 taaagaaagt gatttttttg caacaggtct tattctattt gaatctatat ttaaaaaatt
     5041 gccttttgga gaatcaaatt cagaagaaaa aatgctacaa tctattgata agggattaga
     5101 ttggaatagt ataaaagcaa ttaatggaaa tactgaactt ataaatgtta taaaaaggct
     5161 tcttggaaga aataataagt atactagagc caatgatatt attattgatt taagtaaagt
     5221 aatgtatgaa aaagcatata tagaagttga agatgagaaa gaagaagagc agaaacaaga
     5281 caaagttata caagttaaaa aagaatataa aagtaaaatg agaaaaaaat tacataaaaa
     5341 acttgttgtt gccggtctag ctatagtcat gatttcaatg attattatta gttccataat
     5401 ataaaaattg tatattaagt attttaaaat caatgtctat aaaggatata catagaaatt
     5461 ttagtgtagt cttaaattat gaaaggaagt ggttattatg ttaacaaaaa ataatgaggt
     5521 attaaacgtc taggagtatt ttaacaaata gccacctgct tttacagttt agaataaaaa
     5581 agctgtggct aaaggtcaca gctttttgct actttttaaa ggcaggagaa tattaaaaag
     5641 gagcaaatta tgagcaatat aaaaataata gcaagtaata aatgttggat tgaagatata
     5701 gcaaggaaac aacttgaaga tatttcaaag ttaaatggaa ttttaagagt agtaggatta
     5761 cctgacttac atgcaggtaa aatacctgta ggtttagcag ttgagactaa aaatattatt
     5821 tatccacata taattggaaa tgatatagga tgcggaatga ctttatttaa aactggggtt
     5881 ctaaaaaaga aatttaaaaa agacaaatgg attaagtcac ttagtaagat taaagatttg
     5941 tctgatatag aaataaaaaa cacatataaa gaagaatgtc caattttaaa tttaggaact
     6001 atagggagtg gaaatcattt tgcagaaatt caatgtataa gtgaaattta taataaagaa
     6061 caatttgaac aattaaaatt ttcatctgat gatattatga tgttagttca ctgtgggtca
     6121 agaaattatg gagaagatat tttaaaaaaa ttttatgata aagatggact tgaagttgaa
     6181 agtgagaaag ctatagatta tattaaaaaa catgataatg ctttaatgtg ggcagagcgt
     6241 aatcgtgaag ctatcagtaa aaaaattatg cagtcaatag gtacatctgg agatgttgaa
     6301 acaatattct ctataaatca taattttata gagaaaaggg aagataaatt tatacataga
     6361 aaaggtgctg tttcaagtga aagaggagct gtgattatac caggttcaag aggcagtcta
     6421 tcatatatag ttatgcctac tgaaaataca gagatatctt tatattctct atcacatgga
     6481 gcaggtagaa aatggtctcg ttcagtttgt aaatctcgcc ttaaaagtaa gtatagtaaa
     6541 gatactataa aacaaactaa atttaaaagt cagattatat gtaatgatgt aaatttatta
     6601 tttcaagaag ctccagaggc atataagaat atagagcaga ttattgaaag tttgatagaa
     6661 tatgaactta ttcaagtagt ggcaactatg aagccattga ttacttataa aggataattt
     6721 ttaaagttaa aaaagattaa aattatatta taaatagcta attttatgga acatttaaaa
     6781 gtgttttatt attagctatt tttttatttt gtagagacga taatttatag agctaaattc
     6841 tttgatatat aatgattaca aagttagact gtattggaaa ctgcacatac atgaattgat
     6901 gacaatataa gtgattccca aatataaatg aaagtataag cttattttta ctataaaaat
     6961 tttcactgta caaaaacatt aatgacatta tttttattga cataaatata taatttatgg
     7021 aataatatta gaagcactga tataagtgtt taaataagaa tagaaaagga gaagtgtttt
     7081 atgaaaaaaa atactaacat taatgagtcc ggagttaaac ttcttaataa ataaggagtt
     7141 tgatatataa taactcctta tttattaagt tgttcgcaaa ataactatta tcaaagtaaa
     7201 tgatagggtg atttaaaaga cgatgactta taaataaagg agaaaaaata atgaatagta
     7261 atacatttga aagattacaa ctaaatgaag ttaaagactt aataaaaata cattgtgtaa
     7321 gttcgctagg aaaaaattta atagataaat taactcctag tgggaatatt ggagtagtaa
     7381 gaaggaaatt agcagaaaat aaagaagcta gaaagataat tgaaaatagt aatcacatac
     7441 cacttgaagg attgtttaat gtaggttcta caatagataa aattgaaaaa ggaatgataa
     7501 tagaacctgt tgaacttgta aatattgaag attttttaag aggttgtagg aagatgaaag
     7561 cttttatgtt agaaaaagaa ttttattcac ctacattaag ttcttatgcc ttaaatataa
     7621 cagaatgtaa aagtatagaa gatgagataa attactgtat aaaatctaat aaagttgatt
     7681 ctaatgctag taaagaatta aaaaagataa gacgaaatat agaaattaca gaaggaaaga
     7741 taaaagatag attaaataaa tttataacat caactgtaaa taaaaagtat atacaagagt
     7801 ttataataag taaaagaaat gatagatatg taataccaat taaatcttct tataaaaatg
     7861 aagttaatgg tactatatta gatacatcat caaaaggaaa tactgtattt attgaaccta
     7921 ttagtgtttc aaatttaagt acagagttaa ctatgctaaa agctgatgaa actattgaag
     7981 aatacaaaat attatcttat ttaacagaac ttatatttga gaagataagt cagataaaat
     8041 taaatataga gatactttca gaatacgata tggtatttgc aaaagctaag tatagtcaaa
     8101 aaataaaagg aattactcca aaaataaata ataatggcta tataaaaata attaaaggta
     8161 aacatccact tctaacagga gatgcagtac ctttagattt tgaaataggc aaaaattata
     8221 gaagtcttat aataacaggt cctaatgcag gaggaaaaac tgtaaccctt aagactgttg
     8281 gtttactaac tttaatggtt caatgtggat ttgatatttc tgcaaaagaa ggtagtgaat
     8341 ttagtgtatt tgaaaaagtt tttgtagata taggggataa tcaaagtatt gaaaatgcct
     8401 taagtacttt ttcatcacat ataaaaaata ttgcagagat tatgagttta tcaaataatt
     8461 ctactcttgt tctgtttgat gaaataggaa gtggaactga acctaatgaa ggagctggtt
     8521 tagcaatatc attattagaa gagttttaca aaatgggatg tataactata gcatcaactc
     8581 attatggaga gataaaaaag tttgctacat tgcatccaga atttgaaaat gctggtatga
     8641 tgtttgataa agaaacgtta gaaccattgt ataagttaac tattggaaaa tctgaagata
     8701 gtaatgctct ttttatttct aaaaaaatgg gaataaaaaa tagagtttta gatagagcta
     8761 aagaatatgt aattgataga aactacaatt tagatttagt taaaagaagt aagctacaat
     8821 ctaatattga agataaaaat agttctgaag tcattttaaa ctatacagat tataatgtag
     8881 gggataaggt aaaattacta gatgaagatg attttggaat tgtatataaa cctatggaca
     8941 agtttaataa tgtagaagta ttgtttaatg ataattttat ttcagtaaat ataaaaagat
     9001 tacaacttag cataaaagca tcagaattgt atccagaagg gtatgattta gatgtattat
     9061 ttactagttt taaagaaaga aaattagaaa aagatattca aagaggttca aaaaaagctc
     9121 ttaaaaagat tcagaaagaa attagagaga atagaaaata aatataaaaa gcacaaaaga
     9181 aagcaatcta aagagaaaag tttatcttta gattgctttc ttattaacat atcttcataa
     9241 atccaatgac taacaagatt aaaccactta accaagataa gtttaaattt acgtttttaa
     9301 caaacatatt tcctagtaaa caaccaagta atactgcaat tatatttgat attaaagaaa
     9361 atagaataac ttgtatataa ttcacaccta caaggccact accaaaaccg atagctaatc
     9421 catctaaact taaagcaagt gcaagtgtaa atgcttcagc agatttaagc actttagatt
     9481 tacttgtatc taagacatca ggttcgatac ttacattaaa atttaattta aggtctaaca
     9541 tattaaaatt ataattcttt gagtgtatag attttttctt aaaataagat ttaaaaaaac
     9601 tttcaattag tctagcactt cctaataaaa ataaaataaa gaaacatatt aacattgtta
     9661 tattttgagg taaaaagtct ctaactattg tacctgcaaa aagcgatatt gctaaaatag
     9721 ctgaacaaac tacgctgata attatatttg aatataaggg aactttaact ttatttacgc
     9781 catatccaaa gcttgtcaca aaggcatcta tacaaagaga agtaactaat aaaattgatt
     9841 caatcacagt agattaacat cctttctctt aaattttgta cttatattag ttatagtatt
     9901 gtaaaaatgg ataaattgtt acagataatc caataaattg ttgataaaat tccaacatca
     9961 tacaacacct aaataacaaa agaatcatat catataataa tataaaacca atcataataa
    10021 agcgggtgaa aataatggaa caaaataata aggttgggaa tttcggtgat ttgttgaaga
    10081 ttttattaga tgaaaaagaa ttatcaatgg gagaactaag taaaaaaagt ggaattgata
    10141 aatctactat atctcgtata gctaataata aacaaaagcc aaatataaat catttagaaa
    10201 agatggcaat acatttaaat attaacctag aagaactgtt gaaagcttca ggatatgaat
    10261 ttagaaacag caataatcaa atatttaatg cagatagtga ttttagtaac tttgatgata
    10321 ttcttggatt tgcaaattta atcaatgata agaactttaa tggaaatatt gaaaaagagt
    10381 taagtaagtg taagttatat gtccaaacag atgaaggtaa aaaattactt tttgataatt
    10441 ttaataaaaa aatagattct attgaaaaac aaggtcaatt tacagataga ttaagacaaa
    10501 tgtatgctga tttttgtaca gatggactta caataaagaa atatttattg attggaagta
    10561 tgctacttta ttttgttata tcaacagatg tgattccaga cttcgtattc ccaataggat
    10621 ttatggatga tttagtagca ttaaatatag ttacaaaatt acttaaaaat gataagtaag
    10681 ttttagaatc atatttaata tataaataaa tcaaagtata taaaatttat tattttttat
    10741 atgaaacaaa ttaaaagcac aatgaagtag attaaaaatt taaaactaag aatctaatat
    10801 atattttgta actatttaag tatataaaat aaaataatat ccaaactaat acaaaatagt
    10861 aataattgtt ttgtactgga ggatatatat ttatgaattg taaatggata tctaaaatag
    10921 atgagagaaa aaaatgtcat agagaagcag attcttctgg atattgtatc tttcataaag
    10981 aaaataagtc tgatgaagaa atacagttga tgatggatac tattcataaa gaagagataa
    11041 gtgaatttaa tggatttgtt tttgaaaatg aatttaatgc ggaagaaata ttaacttaca
    11101 attataaaat actggatttt tctgaatcca tatttaaaca aaaagcaaat tttaaaaaat
    11161 atatttttaa aaagaatatt atttttaact atacagaatt tagagataaa gttttattta
    11221 atggttgtgt attcttagaa aactgtgatt ttaatagaag catatttagt aaaaactata
    11281 taaatgaccg tatatttgaa aaagtgaaat ttaaaggacc tgatttggta gttaataaag
    11341 tagaaaattt tccaagaatg gatggaataa tttttagcat gtgtacaaaa tttgtgttaa
    11401 agaatgttga atatggaaaa agtgagtatg agcatggcaa gataaattat agaatagcta
    11461 gaaatcaagc aacaaaaatt ggagaatatg agatgatagg attttactat tataaggaaa
    11521 gaatttatag tagtaaaata atgaaacgtt ctaattatcc tactttcagt gattatttag
    11581 ttgaaaaatt ttttgaccaa atagcacgtt acacaacagg ttatggagaa aagccatgga
    11641 atatattatt agttattata gcaataataa gtgtttttgc tttattatac ttatttgtag
    11701 gcatagaaag ttcaaatagc acacttgtag ctttagatat aaataatata ggtgattact
    11761 cactaagtga gattttcaaa atgtatatgg atttatggta ttttagcatg gctacattta
    11821 gtacagtagg atatggagat atggttgcta caagtttgat tgggaaagca ttggcaggta
    11881 tagaagtatt ttttggagtt acaataggag caatttgggc atctgtgatt attaaaagaa
    11941 tgataaggta atatttgtgt aaatatggat aggtattaat tactagatat aaattggact
    12001 aaatagggaa aatttaaata taaatatact taataatcca agaaggtgaa aaatttgaaa
    12061 aatgcactaa aaaaaattat atcattagcc atgattctag tttttataat accaaattat
    12121 tcatatgcag atgataaatc tgtagacaag tattcaaaaa catctatact tatagaccaa
    12181 gaaacaggta gagttttata tagtaaagaa cctgatatga aggtaccatt agctagttta
    12241 agtaagatga tgactttttt acttgcaata gaagctattg aaaataaaga agtaaaagaa
    12301 actgataaag taaaaataga caaatctatt gcatcagtaa aagggtcaag ttataaactt
    12361 aaagatggtg aagaagtgcc acttatagag cttatgagag gtcttatgat tgtatcagga
    12421 aatgatgcgg caattgctat agcaaaacat atttgtaaaa cgaaagaagc atttgtagat
    12481 agaatgaata aaaaagcaaa agaaatagga atgagtaata cacattttct aaatccaaat
    12541 ggtcttccaa tatacgattt aagcaacccc aaaaaaccag caaaagaaaa tatctctact
    12601 gcaaaagata tagctattct tggaaaatac atgtttgacc attatgaaaa acaagtaaca
    12661 gctataactg atatggagac atatacaaat tcagatagaa gttttgaaaa aagcaataca
    12721 aatgcattat taagaattat accagaagta gatggtataa aaactggata tactggcaat
    12781 gctggatatt gcttatcatt ttctatgatt gtaaataaaa atgataaaaa tgagaaaaaa
    12841 cgtagagtaa taggggttgt attaggtact aaccataaaa ataaaagaac ctctgcttca
    12901 ttagctctac tgaaatatgg aaaagaaaat ttcaatatga aaaaagtaat tgataaagat
    12961 agctttattg gtaagaaata tataaaagga atgaaagagt tagaggttac attaaaagca
    13021 aaagatgaac tttatacaat attaaaagat gatgaaagta taaaatcaga agttaagatt
    13081 aaaaatatag agtaccctgt taaaaaaggt gatactatgg gtattataaa atattatact
    13141 aattcaggtg acttacttgg aagtgtagat atagtaagta ataatagtat agataacgta
    13201 tcattaaaaa caaaattaaa aatgaaattt gcaaattaaa ttcaaaaaat ggtataaaat
    13261 acacaaaaaa atataaaaat agaaaatatg gaaaaaatat tgttatttct tcacctctgt
    13321 gatatactac tagaggtgaa aaaataaaat aaatcacaca cagcattggg atccttaaaa
    13381 ggtgcctatt acatggtttt ttagggagaa gatcaagctg gaggtataaa accaggaggt
    13441 aagatatgtc agtaatatca atgaaacaat tattagaagc aggtgttcac tttggtcacc
    13501 aaacaagaag atggaaccct aaaatggcta agtatatatt cacagagaga aatggaatat
    13561 atataatcga cttacaaaaa acagttaaaa aagttgaaga agcttacaag ttcactaaag
    13621 aagtagctga aacaggaaag ccaatcttat tcgtaggaac taaaaaacaa gctcaagatg
    13681 cgataaaaga tgaagctgaa agatgtggaa tgtactttgt taatgaaaga tggttaggtg
    13741 gaatgttaac aaaccacaaa actataaaaa caagaataaa taaattaaga gaattagaaa
    13801 aaatggaaga agaaggcgta tttaatgttc ttcctaaaaa agaagttata aaattaagag
    13861 ctgaaaaaga aaaactagaa aaatacttag gtggaataaa agacatgcct gaattaccag
    13921 gtgcaatgtt cgtagttgac ccaagaaaag aaaacatagc tattcaagaa gctcatagat
    13981 taggtatacc agtagttggt atagttgata ctaactgtga cccagaacaa ttagactttg
    14041 ctataccagg aaatgatgac gctataagag ccgtaaaatt aataactggt gctatggcaa
    14101 cagctgtaat tgaaggtaga caaggtgctg aggaagaagt agctgaagac caagaataat
    14161 aatttgacaa ttaaatggta agggtcgccc ttaccattta taatatggaa tagaataagt
    14221 aggaggaaac ttaaaaaatg gctaatataa ctgctcaaat ggtaaaagag ttaagagaaa
    14281 gtacaggcgc aggaatgatg gactgcaaga aagctttaca agaagctgaa ggaaacatgg
    14341 aaaaagcagt agatttatta agagaaaaag gattatcaaa agctgctaaa aaagctggta
    14401 gagttgctgc tgaaggtcta gttgcaatag aaatgaatga tgataataca gttgcttcta
    14461 tggtagaagt taactcagag acagatttcg ttgctaaaaa cgaagacttc aaagtgttcg
    14521 ttaaagatgc tgcttgtatg gcattagcta ctgataaaga agatatagct tctttattag
    14581 gtgaaactca taaagaggga ataactttac aagaagtttt aaataataga gttgcaaaaa
    14641 taggtgagaa attagacttt agaagatttg ctaaagttgt aactaatgga caagttgctg
    14701 gatacattca cggtggtgga aaaataggtg ttcttgttga aatggaaaca gaagctagag
    14761 atgctaaagt tttagaatta ggtaaagatg tagctatgca agttgctgct atgaatccta
    14821 agtatgtttc aagagatgaa gtagatgctg aatacatagc acatgaaaca gaagtattaa
    14881 ctcaacaagc tttaaatgaa ggaaaaccag ctaatatagt tgaaaaaatg gttaaaggaa
    14941 gattagaaaa agaattaaaa gaggtttgtt tattagagca aactttcgtt aaaaatccag
    15001 atataactgt taaacaatta gttgctgatg ttgctaaggc agtaggttct gatataaaag
    15061 ttgttaaagt tgtgagattc gaagttggtg aaggtataca aaagagagaa gaaaactttg
    15121 cagaagaagt tgctaagcaa cttaagtaat aaccaaagag agaacacgca ggtgttctct
    15181 tttttaaaaa atagaaaaaa ttggatatga aggattgaaa taggaggttt ctgatggata
    15241 aaccaatgta caaaagggta ttgttaaaat taagtggaga agcattagca ggagaaagag
    15301 gttttggtat aaataatgat gtagttaatg atattgctat tgctataaaa aaaatacaag
    15361 aaataggtgt tgaagtagct gtagtagtag gtggaggaaa cttctggaga ggcagaacca
    15421 gtgaaggaat ggacagaact actgctgact atataggaat gttagctaca gttatgaatg
    15481 caatggcgct acaggatgca ctagaaaata tagatgttgc tacaagagtt caaactgcta
    15541 tagacatgag acaaattgca gaaccatata taagaagaag agcagttaga cacttagaaa
    15601 aggaaagagt tgttatattt ggtgcaggaa caggaaaccc ttactttaca acagatacaa
    15661 ctgctgcttt acgtgctgct gagatggaag cagaagttat attgttagct aaaaatgttg
    15721 atgcagtata tgacaaggat ccaaaagtac atgcagatgc taagaaattt acagaattaa
    15781 gttacatgga agttatacag aaagaattaa aagtaatgga ttctacagct acatctttat
    15841 gtatggataa taaaattcca ataaaggtat ttgagcttac aacagagaat ataataagag
    15901 cagtaaaagg cgaaaatata ggaactactg taaaataatg aagaatgaag gaggagtaaa
    15961 attatgaaac tggaaataca taagcaatta gaagagaaaa tgaatgggac aattgatgct
    16021 ttaaagtttg aatttggaac tataagagca ggaagagcta atgcacaaat gctagacaaa
    16081 ataagagttg attattatgg aactccaact ccaataaatc aaataggtgc tatatctgta
    16141 ccagaaccaa gaatattaat gatatctcct tgggataaat ctgctatgca tgaaatagaa
    16201 aaagcgatag ctaactcaga cttaggatta aatccatcaa atgatggtga ggttataaga
    16261 ctttctgtac ctgctttaac agaagaaaga agaaaagaat tagctaaaaa agctagtaaa
    16321 gctgcagaag aatttaaagt tagaataaga aatgaaagaa gagacgccaa tgagaaaatt
    16381 aaaaagatgg aaaaaggcgg agaattaact gaagatgaat taaaaaaagc acaagatgaa
    16441 gttcaaaaaa tgactgataa atttataaaa gaaatagatg cattattatc taaaaaagaa
    16501 aaggacataa tggaggtata atattgaaaa aatattataa ccttttaggt cttcatgtag
    16561 atgaggtaaa acaatatttt gatgagcaaa atataaatta taccgtaaaa tctattgaag
    16621 gtaaaaagga taaagaaaaa cttgtagttc ctagagttat aaaaatatct gagataggtg
    16681 atagtgtaga actgataatc acatactttt ctgactcctt agtttaagga gtcagaacaa
    16741 tattggaggc aaaatatgaa taacaacatt atatatgata tagacttaaa taacatacct
    16801 actcatattg ctattataat ggatggaaat ggaagatggg caaaagctag atttcttcca
    16861 agaactgcag gacataaggc tggagtagaa actataagag atatagtaaa agaatgctca
    16921 aaattaggtg ttaagcactt aacattatat gcattttcaa cagaaaactg gaaaagaccg
    16981 aaacttgaag ttgacacact tatgaactta ttatctacat acttaagaaa tgaaatagct
    17041 gaacttcacc aaaacaatgt aaaagtaact gctataggag atataagtgc tttaccaaaa
    17101 acttgtataa gagaattaaa ctcagctaag gaactgacaa aaaacaatac aggagttaac
    17161 ttaaatttag cattaaacta cggaagtaga gcagatataa aaaatgctct tatagatata
    17221 gtaaaaaatt gtgaaagtgg taaaatagat ataaacaata ttgatgaaga tattataaaa
    17281 aactatttaa gcacaaagtc tataccagat ccagacttgg taataagaac aagtggtgaa
    17341 caaagattga gtaacttttt actttgggaa gttgcttatt ctgagtttta ctttactgat
    17401 atacattggc ctgattttaa aaaagaagaa ctacagaagg ctatatacgt atatcaaaga
    17461 agggatagaa gatttggagg acttaagtaa ggagattatt ttatgcttac aagaattatt
    17521 gcttcactag ctctggttcc attatttcta tttgttgtat atggaggtat tcctctatat
    17581 atagctgaga cagcaatagt ttatattgca ttgcatgagt tttataaggc atttaaaata
    17641 aaagatgtac atccaatatt cattatagga tatttatttt ctatttattt agctgtaaaa
    17701 aatattttta atttaccatt agaatatact tatgcagtaa tttttatttt atttttagca
    17761 agtataattt atatgttgat gggcaaaaac aatgttatag atgtttcgat tacgttttta
    17821 ggagtttttt atataggagt atttttagat tttataatta taactataaa tggatttgaa
    17881 aaaggtagta tatatgtatg gcttatattt gtgatatctt ttatgacaga tatatttgca
    17941 tattttagtg gttatttact tggaaaacat aagctaattc ctaaagttag tcctaaaaag
    18001 actatagaag gagctattgg aggaataata ggaagtacac tttgttgtat tttatttgga
    18061 tatttatttg gcattgattt gcttcaatta gcgataatag gaagtatagg aagtgtaata
    18121 gctcaattag gagatttatt tgcatcttct ataaagagat atgtagggat aaaggattat
    18181 ggaaagataa tacctggtca tgggggtata ttagatagat ttgatagtgt tatattagtt
    18241 gcaccttttg tatatagtgc gattaaattt tttattagat aaagattggt tggatttaaa
    18301 agagcaatct ataattgcta gtaatgaaaa tagctatgta acttttaaat gcagagatat
    18361 tctgcagtta ttagttacat ggctattttc attgttcaaa aatttagaag accttgggga
    18421 attgtataag aataggtatt actttataat agtatactat atttgtagtg agtatatttt
    18481 ttatactgta actatcatta aaaaatattt ttttgtttaa taatttcgat atttttagct
    18541 ttattata
//
LOCUS       DAYAOO010000081        18541 bp    DNA     linear   BCT 12-OCT-2024
DEFINITION  TPA_asm: Clostridioides difficile isolate ST8-SSI-h139-18
            SAMN40601845-rid21577343.denovo.081, whole genome shotgun sequence.
ACCESSION   DAYAOO010000081 DAYAOO010000000
VERSION     DAYAOO010000081.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN40601845
            Sequence Read Archive: SRR28438827
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 18541)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 18541)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-MAY-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-MAY-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002157583.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002157583.1
            Genome Coverage       :: 163x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/11/2024 16:19:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 4,038
            CDSs (total)                      :: 3,963
            Genes (coding)                    :: 3,930
            CDSs (with protein)               :: 3,930
            Genes (RNA)                       :: 75
            rRNAs                             :: 6, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 60
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 33
            CDSs (without protein)            :: 33
            Pseudo Genes (ambiguous residues) :: 0 of 33
            Pseudo Genes (frameshifted)       :: 7 of 33
            Pseudo Genes (incomplete)         :: 25 of 33
            Pseudo Genes (internal stop)      :: 11 of 33
            Pseudo Genes (multiple problems)  :: 8 of 33
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..18541
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN40601845-rid21577343.denovo.081"
                     /isolate="ST8-SSI-h139-18"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Denmark"
                     /collection_date="2018"
                     /collected_by="Statens Serum Institute"
     gene            402..1805
                     /locus_tag="ACGI5H_003018"
     CDS             402..1805
                     /locus_tag="ACGI5H_003018"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418212.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HFG9698714.1"
                     /translation="MKMLNNFFKKINNPAPVFAQTKMERDNQTDDSLSTKPKTTFRDV
                     AGLDEVKEELFEIVDFMKSPQKYQKMGAKIPKGVLFYGPPGTGKTLLASAVAGETNSS
                     FFNVTGSEFVEKYVGVGAKRVRTLFEKARKEAPSIIFIDEIDAVGAKRHLESNNEKDQ
                     TLNQLLVEMDGFNKDSNVLIIGATNRLDLLDEALLRPGRFDRHIHIGAPNYHTRFEIL
                     KVHTDDKPIDKSVNLELLAKKTHGFNGAHLSNIANEAAIFAVRDDSECITSEHFDKAL
                     ERVIAGLESKNSALVEKEKKIVAYHEAGHALVSDIVGICPIQKISIVPRGQALGYVLQ
                     LPDEDRYIYTKDELIGKIKILLAGKASEELIFNHKSTGAKDDLKKVTEIANQMVCEYG
                     MSNLGFMTIDGNDKTFLCDKVQKEANRIVEICYKETLEMLKDNLEDLHSVSKFLFEKE
                     TMTHEELKDLIGKEAVN"
     gene            complement(2282..3304)
                     /locus_tag="ACGI5H_003019"
     CDS             complement(2282..3304)
                     /locus_tag="ACGI5H_003019"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892750.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HFG9698715.1"
                     /translation="MNQKKVHYNKSATSKDVARLAGVSQSSVSRAFGSANGKGVKPEV
                     RERIFRVANEIGYVPNLVARGMISGKTNVIGLIVGDSLGPFYNRIINLFVEKIQEIGK
                     QCLVFKVPRQQSIDSIISKVIQFQVEAVIITASAMNKVMAETCEENNIPVILFNRFIP
                     GIKISTVYVDPIEGGGMAAEYLLKKGHKNIGYIQFTRETSEEMEKKIGFYSKLRQSGI
                     HNLKEESANYDYDSGYEAGKRMLALSNPPTAIFCTSDLIAIGVMDAARFEYKLRVPED
                     LSVIGYDDIQMASWKSYNLTTIRQPLDLLIEKTINILKSLLNEENPESVVEMLKPELI
                     ERGSTL"
     gene            complement(3339..4937)
                     /locus_tag="ACGI5H_003020"
     CDS             complement(3339..4937)
                     /locus_tag="ACGI5H_003020"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003432878.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sodium:solute symporter"
                     /protein_id="HFG9698716.1"
                     /translation="MISSIDVCIIIGYLLLMLVIGYYSGKDNKNQEDYFLAGRSMPWI
                     PIALSVAATMISANGFIGGPGWAYVDGMYPVMVNITVPLAIFFALSITTPVIYKLKIT
                     SIYEYMGLRLGNYSRGLTIIQFFINSLIQASSMVYIPVLIIQMITGWSLYALVPIVVL
                     VSIIYTLLGGIKAVIWTDSIQMIVVISAVFIVIIVALKGMNLSFFDTLQIAQQSGKLN
                     TFDFSRDISVTNTFWATLIGGTVMWIRYFCFDQSQVQRVLTSKSLKCAKNSFVVSAFV
                     MNLVYYFMLLVGVILFVFYGGRTFETSNEIMITFILNELPVGAIGIIIAGVFAAAMSS
                     IDSILNSMTTVFTKDIYEFYFKKDNKESSLKVTMIITVVIGVVMTGFIIMGFGGSIKS
                     ILDLVGNYISYFAGPATGAFVLAMFTYKANDKGVSIGFIVGLVLGFFISNKYNVSWLW
                     NPAIGATITLIFGYIFSVILKKNHNADDIKKYTAFGMRNHLISQGMDKVDGVSIVPFS
                     LGKQELIVLAFFIIQYIILFLIQF"
     gene            complement(4979..6244)
                     /locus_tag="ACGI5H_003021"
     CDS             complement(4979..6244)
                     /locus_tag="ACGI5H_003021"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429726.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HFG9698717.1"
                     /translation="MKTTVEIENDIILGKDYSNLKRGIAFFSIALIYFFYCYNFMVGT
                     FIKPTMIYALADGGFGFSLKQTEEIFAVMSFGTIPGTFIFGVISTKIGKKRTLISVAL
                     LIGLTTFIPMLSPTNIMLWKIARLCTGVVLGGVFGTAMPLVADMFPSKYRGKLAAILT
                     ALFSLAMIFGGKVYGVLGDANWQILMYTAIIPPIVGAILAIFFVPDDLEYTKELVKKG
                     KETGEKISYISMYKGKYLWIGLGTILLSGANFTAYSAFSNNATTYLVTGIGMSAAVAE
                     SIYSLQGIGQLVGYLFWGSIADKFGRKIPFIGMALAAVFVFIYTKLGGDNTTTFYMIS
                     VLLGVAVGYSGAWGAYYTELFPSKYRSLSSGMSFNGGRIISTFAIPAIAGTASGTLGM
                     MTIFYISIAVFVAGAIVWLFLPETLNNKK"
     gene            complement(6386..7813)
                     /locus_tag="ACGI5H_003022"
     CDS             complement(6386..7813)
                     /locus_tag="ACGI5H_003022"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895719.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ester cyclase"
                     /protein_id="HFG9698718.1"
                     /translation="MASTNKNNATSKEEEKEVSTSGLESCTVKENKAKMNQTNFSNIN
                     ENQTNENKTNTYKRNIDKGNIDKGNIDKTNTNKSDINKVNIDTVDTDKLNTNTLTEKN
                     KKVIFKGEDNMSSTKIYYGDSLEVTPVGVMDYNDFSKQTKREQEIPGFDSKYRDFVDY
                     IMKITHNIWEEKGIGVIYDTYHNNVTMHCGSSNLVGIKDVISNTLQTLHAFPDRRLIG
                     QNVIWSNFGADGFLSSHRVLSTATNLGDSNFGPATGRKINFRTVIDCATTNNRIHEEW
                     LVRDNLWIVTQLGLNPQEVAKSMAKASESKVLSLQSTYGICESMDGQFMPTKYQAKDD
                     SVGEMMLEMTSRIYNYKYINEVKKYYHDNAVVHFICDKDLNGYDEIQGMIVSLFASIP
                     NGSYEVERVTCNQREKNEGYDVSVRWRLRGINEGIGFFGQPSGKHIEVMGINHYHILQ
                     GKVKEEWITFDGMDVLKQIYMGVEE"
     gene            complement(7851..8858)
                     /locus_tag="ACGI5H_003023"
     CDS             complement(7851..8858)
                     /locus_tag="ACGI5H_003023"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895717.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nuclear transport factor 2 family protein"
                     /protein_id="HFG9698719.1"
                     /translation="MGKYQDSKKVVRNYFEALENATGDEVENVLKQHMKSDYNWKGVY
                     PFREQEGTENVADVFWKPLKKSLSNMQRRQDIFIAGTNEIDNSEWVMSMGHFMGLFDN
                     DWLGIKHTRKMISLRYAEFNCVQDGKIAKTGLFVDIIGFMIQAGVNPLPPQTGSYFVY
                     PGPIDHNGLLFEDADEVEGVKTLALVNKMVDDLSELNESGAMGCPPEILEKSWAKDMI
                     WYGPGGIGASYTIPRYQEQHQLPFRNNLKGKTFNGHVCRFAEGNFACFFGWPNLTNVP
                     CGGFLGLPGGEVKADMQVVDVYYRKGDKLQENWVLIDIPYWLKQQGLDILERTKSIFN
                     A"
     gene            complement(9055..10377)
                     /locus_tag="ACGI5H_003024"
     CDS             complement(9055..10377)
                     /locus_tag="ACGI5H_003024"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426892.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9698720.1"
                     /translation="MKILYVGPGMVIDKILAVSKKNFPNIEADFLRYDRYIEVPDLLE
                     KYRGRVDAVLFTGKSPFKFFEKRQKDFVLSDYIPRHETTLYRVLLEITYLLKFDISRL
                     SIDTYDKAMMKRLYKEIGVEFKDEHMFFAEQKYLEEDYIKFVLEFHKYNYQNNDVCCC
                     ITGLEEAYHIMKKDNIPVVLALPSEDVMVQSIKNIQMRYIAKKNNENQIIVLAIKLNM
                     PSEYSLMKEDEYAYLSQRIKILDKLYHFNSRIDGVLVEQSRSEFMIFTTKKILELETK
                     KYRDIYLLDMIREVSVINTYIGIGYGKTANEAKFNAYESIKMAQSQKNDAAYVVFENG
                     EIMGPLKPNPTVKEKNSFDERFYQIATETGLSANTVYKVFNKIINSGKTEFTSKELAT
                     ICGVSIRTMDRIILRLCDSGYCEVVSEQLMSKYGRPSRILRFKPFLLF"
     gene            complement(10735..12375)
                     /locus_tag="ACGI5H_003025"
     CDS             complement(10735..12375)
                     /locus_tag="ACGI5H_003025"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439153.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidohydrolase family protein"
                     /protein_id="HFG9698721.1"
                     /translation="MFDVKIVNGIIVDGTGNSRYKSDVGIVGDKIMAIGDLSQKEAKE
                     TIDATGKFVSPGFIDFHTHSDLSLVYDKYTRSRIHTGVTTDVIANCGIGVAPIREEKK
                     QELIDYLGTRIIGTIPTKLELHWNTMQEYFDYLTENSPAVNVVAYVAQGPVRINEMGF
                     SKEPATLEQLKNMKLEVRKAMEAGCVALSSGLVYLPGAYTKKEEMAELCKELIPYNGY
                     YISHIRDEGDEEMEALDEAIYIAKTAGVPLHISHLKVMGHKNFGTIDEVFKKLDEAEA
                     DGLEVTFDCYPYTAGMTSLGALLPPWAFEGGVENMVKRLEVQENRDRIIKELEEGIPG
                     WQCFYQLAGGWNGVVLASVMTEANKYVEGKTLMEVAKINGENPFDTFFRLLIEEKSKI
                     QVVVHTQGQEDTDKVVCHPKSCIGSDSMDLSTEGLLSLGKPHPRAFGTFGRIFSYYVR
                     EKGMLTFEEAVKKITYLSAKRLGIYKERGLLKENYFADIVVFDPDTIEDKATYSNPKQ
                     YTVGVEYVLVNGKIALAGGKQTDVCAGRVIKNPLSIAK"
     gene            complement(12531..13187)
                     /locus_tag="ACGI5H_003026"
     CDS             complement(12531..13187)
                     /locus_tag="ACGI5H_003026"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426890.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9698722.1"
                     /translation="MYDKKMIKIGRISIGLAIIANFIPAIYVGIRFGQMPMLSVIFQI
                     WGLVAATYGVSWIVQPIAYYPTLGAPGSYIGWLAGSVGDIRMPAASMAQKIAGVEAGT
                     HEGEVVGTIGTCCSIFVSASMITIFTIVGYKVIPLLPEFVTNSFNYILPALFGAIYVD
                     IARKDIRAGGCTIAVALAIMYFGEKIGIPGGLLTLFIVLGGILITRVFFVIDNNKTKE
                     "
     gene            complement(13213..13914)
                     /locus_tag="ACGI5H_003027"
     CDS             complement(13213..13914)
                     /locus_tag="ACGI5H_003027"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729445.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF5058 family protein"
                     /protein_id="HFG9698723.1"
                     /translation="MKFQEMINSPGLWIVSSFLVIISVVQAIVFMKEALKEASNLGIE
                     KKGIKAAIRSASVTAIGPSLSPVITLLSLVAVIGAPTTWMRLCDVGAARTELGVISLT
                     SNLSGVEVGSAAFGAEAFSYALWGMALNNLGWLFVVFILGHRMRGIVEKMNMKYNPTW
                     VKKLLAGATVGLFAYLLSNQIKTFEIPKLTPAIISAIVMLVLTTLFKKNQRLQELSLG
                     IAMLIGMFGTQIILS"
     gene            14722..15201
                     /locus_tag="ACGI5H_003028"
     CDS             14722..15201
                     /locus_tag="ACGI5H_003028"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895709.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_function: GO:0016987 - sigma factor activity [Evidence
                     IEA];
                     GO_process: GO:0006352 - DNA-templated transcription
                     initiation [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-70 family RNA polymerase sigma factor"
                     /protein_id="HFG9698724.1"
                     /translation="MDKTTFTNNILESEQTLYRVSKSILGNDQDCEDAVNNAILKAYE
                     KLDSLKEEQYFKTWLIRIVINECNSLRRKRLKSLSFEDVFKNKKIDEKDDYSDLYTAI
                     QSLPKKIKIPIVLYYIEGYSVDEVKEILDIPQGTVKSRLSRGRRLLKTKLENTEVII"
     gene            15198..15977
                     /locus_tag="ACGI5H_003029"
     CDS             15198..15977
                     /locus_tag="ACGI5H_003029"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895707.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9698725.1"
                     /translation="MNKNILNNSFPEVPESFHNSLSKTLNSLPEREENYKMINNKTHK
                     LPFRKGLVATLAITLILSTTALAVGHIYSLVGKSSTKATYTSIPTTEQVKKDFNFTPN
                     IVSEFSNGYKFKGAYTVNKKAFDKENNVLGKSKALSFEYKNGNDEISLDTANNVLGKS
                     SDNLKVVDTYKDINISYEAFAQKFIPEGYKMTEQDKIDEKSGKYTFSVGPNNESDKVE
                     VNEFKFLTWKQDGVYYSFTVQDSNLSMNDLVKMAHEVIDAK"
     gene            complement(16227..16727)
                     /locus_tag="ACGI5H_003030"
     CDS             complement(16227..16727)
                     /locus_tag="ACGI5H_003030"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418206.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetyltransferase family protein"
                     /protein_id="HFG9698726.1"
                     /translation="MIEGIKFIKAEEKYIYSYWQTFDKIAKERKYLAMDEAFPFEETV
                     EFIKNIINKNLPQLFIIDLESDNCIGWCDVLPKTEKVGYLGMGILKEYREKGIGSSLL
                     KQIIDLSKEYGYEKIELDVFKSNSRAIHVYKSLGFVEVNTISSGFTWNDRPVKEEVIQ
                     MELTLI"
     gene            complement(17339..18046)
                     /locus_tag="ACGI5H_003031"
     CDS             complement(17339..18046)
                     /locus_tag="ACGI5H_003031"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426879.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008757 - S-adenosylmethionine-dependent
                     methyltransferase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="methyltransferase domain-containing protein"
                     /protein_id="HFG9698727.1"
                     /translation="MIFTKSNKYDKDFLMKNMMGPNCIKILEELTSKIKLEKGMRILD
                     LGCGKGISSIFLAKEFDATVFATDLWIEPTENYKRFKEFKLDDKIFPIQAEAHELPYA
                     EGFFDAVISIDSYHYFGNKEGFLDNHISPLVKEGGILAMAMPGLKEDFVDCIPDELIP
                     FWQDNMNFHSITWWNKLWSESESVIVEKCEALNCHDEAWKDWINCDNSYAINDKKMME
                     VENGKYFNTISLIARTK"
BASE COUNT         6418 a         3307 c         2136 g         6680 t
ORIGIN      
        1 aacaaatcct ataattatat tctaatatac tacctactac tttgcgctac aacaatttct
       61 ctatttatat gatttgtaaa atatagtaca acatttttta tcattttcat ttcaactaaa
      121 tttgtaatat tttattcaat acttaataaa tacttaatca atacatgctt tataatactt
      181 tactcaatat ataatcaata cataatttat aatttgtaat actttattca atacataagt
      241 agaaatctct atatacataa attcattttt tcatacatct tacaaattta tttttattta
      301 gataacatgt atattttttc catgaaaaat aaataataaa aaatagtaaa tatggaaaat
      361 ataaaattga ttaacaataa ttaattacct gaggtgtgaa tatgaaaatg ctaaacaact
      421 tttttaagaa aatcaacaat ccagctcctg tctttgcaca gacaaaaatg gaaagagata
      481 atcaaacaga tgattcactt tctacaaaac caaagactac atttagagac gttgctggat
      541 tagacgaagt aaaagaagaa ctatttgaaa tagtcgattt tatgaagtca ccacaaaaat
      601 atcaaaaaat gggtgcaaaa atacctaaag gagtattatt ttatggtcct ccaggaacag
      661 gtaaaaccct acttgcatct gctgtagctg gtgaaacaaa ctcatcattt ttcaatgtta
      721 ctggttcaga gttcgttgaa aaatatgtag gtgtgggagc aaaaagagtt agaactctat
      781 ttgaaaaagc tagaaaagaa gctccaagta taatatttat agacgaaata gatgctgtag
      841 gagcaaagag acatcttgaa agtaacaacg aaaaagacca aacactaaac caacttttag
      901 ttgaaatgga tggatttaat aaagattcca atgtattaat aataggtgct accaatagac
      961 ttgacttatt agatgaagct ttacttagac caggaagatt tgacagacac attcatatag
     1021 gtgcaccaaa ctatcacact agatttgaaa ttctaaaggt acatacagat gacaaaccta
     1081 tagacaaatc tgtaaatcta gaacttttag ctaaaaaaac tcatggtttc aatggggctc
     1141 atctttcaaa tatagcaaat gaagcagcta tatttgcagt tagagatgac agtgagtgta
     1201 ttacatcaga acattttgac aaggcacttg aaagagttat tgcagggcta gaatctaaaa
     1261 actctgcatt ggttgaaaaa gagaaaaaaa tagtagcata tcatgaagct ggacatgctc
     1321 ttgtaagtga tatagtagga atttgtccta tacaaaaaat atctatagtt cctagaggac
     1381 aagcattagg ttatgttctt caattacctg atgaagatag atatatttat actaaggatg
     1441 agttgattgg aaaaataaaa atattacttg ctggaaaggc ttcagaagaa ttaatattta
     1501 atcataaatc tactggtgca aaggacgact taaagaaagt cactgaaata gctaaccaaa
     1561 tggtttgtga atatggtatg agtaacttag gatttatgac tattgatgga aatgataaga
     1621 ctttcttatg tgataaggtt caaaaggaag caaatcgtat agttgaaatt tgttataaag
     1681 agactttaga gatgttaaag gataatcttg aagatttaca ttctgtttct aaattcttat
     1741 ttgaaaaaga aactatgact catgaagagt taaaagattt gataggaaaa gaagctgtaa
     1801 actaatatag ttttaaaaat ttgaggctgt ctcaaaatag agataagcct ctttttattg
     1861 ttaaagttat aaaaatacat ttgattttat acaaaaaagt gcctcataaa ctaaaaattt
     1921 cattttgaga cacttacata ttttaattac atattttaat tttgtctatt tacagaatat
     1981 tatatctaca taaaactaaa ctgctgtaaa cttaactacc tccagtaatg tttgaagtgg
     2041 tataaaagct agtagcctag tttctacact tataatttat attttacata actaaattta
     2101 gtagattttt atactcacaa tttagaacga ttgaaaactt aaaaatttct tatcagatat
     2161 ctacaactta attaggtatc tatcacttga ttaaatatct atcacttaat taggtatcta
     2221 tcacttgatt aaatatctgc catttaatta aatatctacc acttaattaa atatctacca
     2281 cttaaagtgt agaacctctt tcaatcaatt caggttttaa catttcaacg actgactctg
     2341 gattttcttc atttaataag gacttaagta tgttaattgt tttttcaatc aacaaatcta
     2401 gtggctgtct aatcgtcgtt aaattataac tcttccatga agccatttga atatcatcat
     2461 atcctatcac tgataaatcc tctggcaccc tcaacttgta ctcaaacctt gcagcatcca
     2521 ttacaccaat agctatcaag tcacttgtgc aaaaaattgc tgttggagga tttgataatg
     2581 ctaacattct cttacctgct tcatatccag aatcataatc atagtttgca gattcttctt
     2641 taaggttatg aatcccactt tgtcttaact tagagtaaaa tccaattttc ttttccattt
     2701 cttcacttgt ttctctcgta aattgaatat atcctatatt cttatgacct ttcttaagca
     2761 gatattcagc agccattccc ccaccttcaa ttgggtctac atagactgta cttattttta
     2821 taccaggtat aaaacgatta aaaagaatca caggaatatt gttttcttca caagtctcag
     2881 ccatcacctt attcatggcc gaagctgtaa taatcacagc ttctacttga aactgaatta
     2941 cttttgaaat tatactatct atactttgtt gtctaggaac tttaaaaacg agacactgtt
     3001 tacctatctc ttgaattttt tctacaaata aattgataat tctattgtaa aatggaccta
     3061 gactatcacc aactatcaat cctataacat tagtttttcc actaatcatt ccccgtgcta
     3121 ccaaattagg aacatatcct atttcatttg ctacacgaaa aattctttct cttacttcag
     3181 gttttacgcc ctttccattt gcactaccaa atgctcttga aacagatgat tgagatactc
     3241 ctgccaatct tgcaacatct tttgaggtag ccgatttatt ataatgaact ttcttttgat
     3301 tcatttagta tttctcctta aatatctagt atttcttctt aaaattgtat caaaaataat
     3361 ataatatatt ggataataaa aaaagctaat acaattaatt cttgtttacc taaagaaaat
     3421 ggcactatag atactccatc tactttatcc attccttgag aaataaggtg atttctcata
     3481 ccaaatgcag tgtatttttt aatatcatct gcattatgat ttttctttaa aatgacacta
     3541 aaaatatatc caaatatcaa tgttattgta gcacctattg ctggattcca caaccaactc
     3601 acattatatt tattagaaat aaaaaatcct aaaactaacc ctacaataaa accaatagat
     3661 actcctttat cattagcttt atatgtaaac attgctagta caaatgcacc tgtagctggt
     3721 ccagcaaagt atgagatata gttaccaaca aggtcaagaa ttgatttgat gcttcctcca
     3781 aatcccataa taataaaacc tgtcataaca actcctataa ctacagttat aatcattgta
     3841 acttttaatg atgattcttt gttatctttt ttgaaataaa actcataaat atccttcgta
     3901 aaaacagttg tcatactgtt taatatagag tcgatactag acattgctgc tgcaaacaca
     3961 cctgcaataa taattccaat ggctcctact ggaagttcat ttaaaataaa agtaatcatt
     4021 atttcatttg aagtttcaaa tgtccttccc ccataaaaaa caaataaaat tactcctacc
     4081 aatagcataa agtagtaaac taaattcata acaaatgcac taactacaaa agaatttttt
     4141 gcacatttta aagatttaga tgttaaaact ctttgtactt gagattggtc aaaacaaaag
     4201 tatcttatcc acattacagt tccaccaatt aaagtagccc aaaaagtatt tgtcactgaa
     4261 atatccctac tgaaatcaaa tgtatttaat tttccactct gttgtgcaat ttgtaatgta
     4321 tcaaagaaac ttagattcat tccttttaag gctacaataa ttactataaa tacagcactt
     4381 attactacta tcatttgaat actatcagtc catataactg ccttaatccc acctaataga
     4441 gtgtatataa ttgatacaag tacaactatt gggactaaag cataaagtga ccagccagta
     4501 atcatttgaa taataagcac tggaatatat accatagaac tagcttgaat caatgaatta
     4561 ataaaaaatt gaataatagt taatcctctt gaataatttc ctaaacgaag tcccatatat
     4621 tcatatatag aggttatttt taatttatag ataactgggg tggtaatgct cagtgcaaaa
     4681 aatattgcta aaggtactgt aatattaacc attactggat acattccatc tacatatgcc
     4741 catccaggac cacctataaa gccatttgca ctaatcatag tagctgcaac tgataaagca
     4801 attggaatcc atggcattga cctacctgcc aagaaataat cttcttgatt tttattatct
     4861 tttcctgaat aataaccaat aactaacatt aatagcaaat atcctattat aatacataca
     4921 tcaattgatg aaatcataag ccaccccttt ctaagtaaca aaataaattc ctagtatttt
     4981 attttttatt atttaacgtc tctggtaaga ataaccatac aatagcacct gctacaaaga
     5041 ctgcgattga tatgtaaaag atagtcatca tacctaaagt accagaagct gtaccagcta
     5101 tagcaggtat tgcaaacgta gatataatcc ttcctccatt aaatgacata ccagatgaca
     5161 acgaacgata tttacttggg aacaactctg tgtagtatgc tccccatgct ccagaatatc
     5221 caacagcaac acctagtaat actgatatca tatagaatgt tgttgtatta tctccaccta
     5281 attttgtata tataaaaaca aatactgctg ctaatgccat acctataaaa ggtatttttc
     5341 ttccaaattt atctgcaatt gaaccccaga ataaatatcc tactaattga ccaattcctt
     5401 gtaaactata tatagactca gccactgctg ctgacattcc tattcctgtc actaggtatg
     5461 tagttgcatt atttgaaaat gctgaatatg ctgtaaaatt tgcacctgat aaaagaatcg
     5521 ttcccaatcc aatccataag tattttccct tatacatact tatatagcta atcttttcac
     5581 cagtttcttt tcccttttta actaattcct ttgtatactc caaatcatct ggcacaaaga
     5641 agattgctaa gatagctcca actataggtg gtataatcgc agtatacatc aatatttgcc
     5701 aatttgcatc acctaaaacg ccatatactt tcccaccaaa aatcattgct aatgaaaata
     5761 aagcagttaa tatagcagct aacttaccac gatatttact tggaaacata tctgcaacta
     5821 aaggcatagc tgttccaaat acgcctccca acactactcc tgtacacaaa cgtgctattt
     5881 tccataacat aatatttgta ggagataaca ttggtataaa tgttgtcaat ccaatcagta
     5941 aagcaacgct aattaaagtc ctcttcttcc caatttttgt agaaatcacc ccaaaaataa
     6001 atgtacctgg aattgtacca aaagacataa ctgcaaatat ttcttctgtt tgttttaatg
     6061 aaaaaccaaa tcccccatct gctaaagcat aaatcattgt tggtttaata aaagtaccca
     6121 ccataaaatt gtagcaataa aaaaagtata ttaaagcaat tgaaaaaaat gcaattcctc
     6181 tttttaggtt tgaatagtct tttcctaata tgatatcatt ttctatttca accgttgttt
     6241 tcatattttt ataattcccc cttttaaatt tagtcataat tttgctaaaa gtttaaacat
     6301 ctatttttca tatacattcc ccacttaaat tttataaagc aatacttccc tatatatttc
     6361 aaaactattt atactctaaa cagctttatt cttctactcc catataaatt tgttttaata
     6421 catccatacc atcaaaagtt atccactcct cctttacttt accttgtagt atatgataat
     6481 gattgattcc cattacttct atatgctttc cagaaggctg tccaaaaaat cctatacctt
     6541 catttattcc acgtaatctc catcttacag atacatcata accttcattt ttttctcttt
     6601 gattacaagt tactctttcc acttcataac ttccatttgg aattgatgca aataaactta
     6661 caatcattcc ttgaatctca tcatagccat ttaaatcttt atcacatata aaatgtacta
     6721 ctgcattatc atgatagtat tttttaactt catttatata tttataatta taaatacggc
     6781 ttgtcatttc aagcatcatt tcgccaacag aatcatcttt tgcttgatac ttagttggca
     6841 taaattgacc atccatagat tcacagatac cataagttga ttgtaaacta agcactttag
     6901 attcacttgc ctttgccata ctctttgcta cttcctgagg gtttaatcct aattgagtaa
     6961 caatccataa attatctcta accaaccatt cttcatggat tctattgtta gttgtggcac
     7021 aatcaattac agttctaaag tttatttttc tacctgttgc tggtccaaaa ttactatcac
     7081 ctaagttagt tgctgtagac aaaacacggt gagaagataa aaaaccatca gcaccaaagt
     7141 tagaccatat tacattttga ccaattaatc ttctatcagg aaacgcatgt aatgtttgaa
     7201 gagtattgga aataacatct ttaataccaa ctaaatttga agagccacaa tgcattgtaa
     7261 cattattgtg atatgtatca taaataacac ctataccttt ttcttcccag atattatgtg
     7321 taatcttcat aatataatct acaaaatctc tatacttaga atcaaatcca ggtatttcct
     7381 gttccctttt tgtctgtttt gaaaaatcat tgtaatccat tactccaaca ggcgttactt
     7441 ctaatgaatc tccatagtaa atttttgtag atgacatatt atcttccccc ttaaatataa
     7501 cttttttatt tttttcagta agagtatttg tatttaattt atctgtatcc actgtatcta
     7561 tgttaacttt atttatgtcg gatttatttg tgtttgtttt atctatattc cctttatcta
     7621 tatttccttt atctatattt cttttatatg tgttcgtttt attctcattt gtttgatttt
     7681 catttatatt actaaaatta gtttgattca ttttagcttt gttttcttta accgtacatg
     7741 attcaagccc acttgtagaa acttcttttt cttcctcttt acttgttgca ttatttttgt
     7801 tggtagatgc cactttatat ccccctttgt tttagaatac gtatgcataa ctaagcatta
     7861 aaaatacttt tagttctctc aagaatatca agcccttgtt gtttcaacca ataaggaata
     7921 tcaattaaca cccagttttc ttgaagttta tcgcccttac gataataaac atcaacaact
     7981 tgcatatctg ctttaacctc tccacctggt aatcctaaaa aacctccaca tggtacatta
     8041 gtcagattag gccatccaaa gaaacaagca aaattacctt ctgcaaatct acatacatgc
     8101 ccattaaaag tctttccttt taaattattt ctaaatggta gctggtgttg ctcttgatat
     8161 ctaggtatag tataagaagc accaattcca cctggaccat accaaatcat atctttagcc
     8221 caagattttt caagtatttc tggtgggcat cccatagcac cactttcatt tagttcagat
     8281 aaatcatcta ccattttatt tactaatgct aaagttttta ctccttcaac ttcatctgca
     8341 tcttcaaaaa gtaatccatt atggtcaatt ggccctggat atacaaaata tgaacctgtt
     8401 tgtggtggca atggattaac tcctgcttga atcataaacc caattatatc tacaaataat
     8461 ccagttttag caattttacc atcttgaaca cagttaaatt ctgcatatct taaactaatc
     8521 attttacgag tatgtttaat gccaagccaa tcgttatcaa aaagtcccat aaaatgcccc
     8581 atactcatta cccattcact attgtcaatc tcatttgttc ctgcaatgaa aatatcttgt
     8641 cgtctttgca tattactcaa tgattttttt aaaggcttcc aaaatacatc tgctacattt
     8701 tcagtgcctt cttgttcacg aaatggatac acacctttcc agttataatc tgatttcata
     8761 tgttgcttta agacattttc aacctcatcc ccagtagcat tttctaatgc ttcaaaataa
     8821 tttcttacaa ctttttttga atcctgatat tttcccataa ttatctcctc ccagatttat
     8881 ttaagttata aattaacttt ctcatttcat gcatacgatt tcctttttaa tgatttttta
     8941 gctgttttaa gtttatttta tgaatacata tgcatttttc taaatattaa catatatcta
     9001 aaaaattgta aagaaaatgt tatcataaaa atttaatttt tgacttatat ctatttaaaa
     9061 caacagaaaa ggtttaaaac gtaatattct actgggtcta ccatacttgc tcataagctg
     9121 ttcactcact acctcacaat aaccagaatc acacaatcta agtataatcc tgtccatagt
     9181 tctaatactt acaccacata tagtagctaa ttcctttgat gtaaattcag tttttccact
     9241 atttattatt ttattgaata ctttatatac agtattagca cttagccctg tctctgtagc
     9301 aatttgataa aaacgttcat caaaactatt tttctctttg acagtaggat ttggctttag
     9361 tggtcccata atttctccat tttcaaaaac tacatatgct gcatcatttt tttgactttg
     9421 agccatctta atactctcat aagcgttaaa tttagcttca tttgctgttt ttccataacc
     9481 aattcctata taagtgttta taactgaaac ttcacgaatc atatccaaca aataaatatc
     9541 tctgtatttc tttgtttcta actcaagtat ttttttagtt gtaaaaatca taaattcact
     9601 tctactctgc tctaccaaaa caccatctat acggctattg aaatggtata gtttatcaag
     9661 aatcttaatc ctttgtgaaa gataagcgta ctcatcttcc ttcattagtg aatattctga
     9721 aggcatgttc agtttaatag caagaacaat aatctgattc tcattgtttt tctttgcaat
     9781 ataacgcatc tgaatgtttt ttatactttg caccattacg tcctcagaag gcaaggctaa
     9841 aactactgga atattatctt ttttcattat atgataggcc tcttcaagac ctgtaataca
     9901 acaacataca tcattatttt gataattata tttatgaaat tcaagcacaa actttatata
     9961 gtcctcttct aaatactttt gctctgcaaa aaacatatgt tcatccttaa attcaactcc
    10021 aatttcttta tacaatctct tcatcatagc cttatcataa gtatctatac taagtctact
    10081 aatatcgaat ttaagcaaat atgtaatttc aagcaacact ctgtacaatg ttgtttcatg
    10141 tctaggaata taatcagaca atacaaaatc tttttgtctt ttttcaaaaa atttaaatgg
    10201 cgacttacct gtaaaaagaa ctgcatccac tctacctcta tatttttcca ataaatcagg
    10261 tacttcaata tatctatcat atctaagaaa atctgcttca atattaggaa aattcttttt
    10321 acttactgct agtattttat cgattaccat acctggtcct acataaagta ttttcatttc
    10381 gtctctcctt tcctaatgat actattatct cttaaaacat tttctaaacc taccatgact
    10441 aaagccacag gactcctgat tcatagaatt ttgaataatc aattatacct aatataaaaa
    10501 gttactttaa gttttttaat tacgactatc tgttgaaaca tttttgtatt taaatttttg
    10561 tatttaaatc ttattcatta atattaatta cattttacaa ttaatatatt gttttttcta
    10621 cttaaagtta aattctttag aaaacacaag tagagtaatc tttattaatt taacaaaaat
    10681 agccttcctt aatattcaaa gaaagactat ttttataaaa gttcttaatg tattctattt
    10741 tgctatgcta agaggatttt taattacacg tccagcacat acatcagttt gctttcctcc
    10801 tgccaatgca attttaccat tcaccaacac atattccact cccactgtat actgtttagg
    10861 attactataa gtcgctttat cttctattgt atctgggtca aataccacaa tgtcagcaaa
    10921 ataattttct ttaagtagac ccctttcttt ataaatgcct aagcgttttg ctgaaagata
    10981 agttatcttt ttaactgctt cctcaaaagt caacatacct ttttctctaa catagtaaga
    11041 gaaaattcgt ccaaaagtac caaatgcacg aggatgaggc tttccaagag aaagtaaacc
    11101 ttctgtagaa aggtccatac tatcagaacc tatacatgac tttggatggc aaacaacctt
    11161 atctgtatcc tcttgacctt gtgtatgaac aactacttga attttacttt tttcttcaat
    11221 caaaagccta aagaacgtat caaatggatt ttcaccattg attttggcta cctccattaa
    11281 agttttaccc tctacatatt tatttgcttc agtcattaca gaggctagta caacaccgtt
    11341 ccacccacct gctaattggt agaaacattg ccatccagga atcccttcct ccaactcttt
    11401 tataattctg tctctatttt cttgtacttc taatcgtttt accatatttt ctacaccgcc
    11461 ttcaaaagcc caaggaggta aaagtgcacc caaagatgtc attccagctg tatatgggta
    11521 acaatcaaaa gttacttcca aaccatctgc ctcagcttca tctagctttt taaatacctc
    11581 atcaatagtt ccaaaattct tatgacccat aacttttaaa tgagaaatat gtagaggaac
    11641 tcctgcagtc ttagctatat aaattgcttc atcaagagct tccatttctt catcaccttc
    11701 atctctaata tgagatatat agtatccatt gtatggtatc aattccttac ataattcagc
    11761 catttcttct ttctttgtgt atgctcctgg taaataaact aatcctgatg aaagagctac
    11821 acatccagct tccatagctt ttctaacttc caacttcata tttttaagtt gctctaaagt
    11881 agctggttcc tttgaaaatc ccatttcatt gatacgtaca ggtccttgtg ctacataagc
    11941 tacaacattg actgctggag aattttcagt taagtaatca aagtattctt gcattgtatt
    12001 ccaatgaagc tctaattttg ttggaattgt accaattatc ctagttccaa gataatcaat
    12061 taactcttgc ttcttctctt ctcttatcgg agcaactcct ataccacagt ttgcaataac
    12121 atctgttgtt acacctgtat ggatacggct tcttgtgtat ttatcataca caagagataa
    12181 atcagaatga gtatggaaat ctataaaacc aggtgataca aattttccag ttgcgtctat
    12241 agtctcttta gcctcttttt gacttaaatc tccaatagcc atgattttgt ctcctacaat
    12301 ccctacatca cttttatatc ttgaatttcc tgtaccatca acgattattc cattgacaat
    12361 tttaacatca aacatgcttt ttctcctttc aagacttatt tatattcata tttcttaata
    12421 aacaatccta ttcttttttc tcaacaaata attctagtct ttctccttaa taaacaatcc
    12481 tattcttttt ctcaacaaat aattctagtc tttctcctta ataagcaatc ctattctttt
    12541 gttttattgt tatcaattac aaagaagacc cttgtgataa gtatcccacc taacacaata
    12601 aacaatgtta ataatccacc tggtatacca attttttcac caaagtacat aattgctaac
    12661 gctacagcaa tcgtacatcc accagctcga atatccttac gtgcaatatc aacataaatt
    12721 gctccaaata atgctggaag tatataatta aatgaattag taacaaattc aggtaacaaa
    12781 ggaattactt tatagcctac aatggtaaaa atggtaatca tagaagctga tacaaagatt
    12841 gaacaacatg taccaattgt tccaacaact tcaccctcat gagttcctgc ttctacacct
    12901 gcaattttct gtgccattga tgctgcaggc atacgtatat ctccaacaga acctgcaagc
    12961 caacctatat aagaacctgg agctcctagt gtaggataat aagctatagg ttgaacaatc
    13021 caactaaccc cataagtcgc agcgactaac ccccaaattt gaaatataac agaaagcatt
    13081 ggcatctgac caaagcgaat acctacatag atagcgggaa taaagtttgc aataattgca
    13141 agacctatag aaattctccc tatttttatc atctttttat catacataat tatcacctct
    13201 tatccgtttt aatcacgata atataatctg tgtaccaaac ataccaatta acatggcaat
    13261 acctaaggat aattcttgta atcgttgatt ctttttaaat aaagttgtca atactagcat
    13321 aactatagct gaaataattg ctggtgtaag ttttggtatt tcaaatgttt ttatttgatt
    13381 tgaaagaagg taagcaaata atccaactgt agcacctgca agtagttttt taacccaagt
    13441 aggattatac ttcatgttca tcttttcaac aattccacgc attctatgac ccaaaataaa
    13501 tacaacaaat agccaaccta agttatttaa agccatcccc catagtgcat acgaaaaagc
    13561 ttctgctcca aatgcagcac tacctacttc taccccagat aaattggatg taagagatat
    13621 tactccaagc tctgttctag ctgctccgac atcacagagc ctcatccaag tcgtaggagc
    13681 gccaatcaca gctaccagtg ataataatgt aataacagga gatagagaag gtccaatggc
    13741 tgtaacacta gctgagcgaa ttgctgcttt aattcctttc ttttcaatac caagatttga
    13801 agcctctttt agtgcctctt tcataaatac gattgcttga acaactgaaa taattactaa
    13861 aaaactagaa acaatccaaa gacctgggct attaatcatt tcttgaaact tcatacttta
    13921 ttcctcctta aaataaattt ttcagcattt tattgtgagc tttctttctg taatcttgtt
    13981 atgtttttat attgttttaa tttattttat ctaagatata gtatctttaa taggagatta
    14041 tctgtcttaa agtctcacta aaaacattaa tacttaaata ttttattcat aattagtaaa
    14101 tatcagaaaa ttcacatatt atttttttaa cctgtaatta acttataagg tcttttatta
    14161 ttttgacatt tcaatataaa aattttaatc aaaaaacttt attattttaa aaaaaattat
    14221 tatttttata atttatattt tttaagttta tttatgttca tctctatcta aaataatgac
    14281 atttctaact cttaattctc atttaagttt cattgttttt tcttaaaagc ctacttttag
    14341 tcaagatact gttatcttta ctcattattt aaagaactta ttttaaatct gtacatgaag
    14401 taaataatcc aaaagcattg ttattctaac tactcaacat taaatactta ctattttcta
    14461 attactcaat ataaagactt actataaaac taaatacata aatggcttct aaagtttaat
    14521 atatctacat ggctttatat atgacaggaa aaatactaga aaaaatatat tatagaatac
    14581 ttgtatataa taggcaaaac tttcaaactt aaatttatca aataatcata aaaaaagtga
    14641 accatctata gtaaaatttt atctaataag tgaaaggcaa aaaagtagcg ctacgatttg
    14701 catagaaggg aaggaactta gttggataaa actacattta caaacaatat acttgaatca
    14761 gaacagactt tgtatcgagt atctaagtct attctaggaa atgaccaaga ctgtgaagat
    14821 gccgtcaaca atgctatttt aaaagcatat gaaaagttgg attctcttaa ggaagaacaa
    14881 tactttaaaa catggctgat tagaatagtc ataaatgaat gtaattcatt aagacgcaaa
    14941 cgattaaaat ctctatcatt tgaagatgtc ttcaaaaaca aaaaaattga tgaaaaagat
    15001 gactatagcg atttgtatac tgctattcaa agtctaccta aaaaaattaa aattccaata
    15061 gtcctttact atattgaagg ttattcagta gatgaagtta aggaaatatt agatatacct
    15121 caaggaactg taaaaagtag attatcaaga ggaagaagat tattaaaaac taaattagaa
    15181 aacacagagg taatcatatg aataaaaata tattaaataa ttcgtttcca gaagttccag
    15241 aaagttttca taatagttta agcaaaacac taaatagttt accagaaaga gaggaaaatt
    15301 ataaaatgat taataataaa acacacaaat taccatttag aaaaggctta gttgcaactt
    15361 tagccattac tttgatattg agcacaacag cccttgcagt aggacatata tatagtttag
    15421 ttggaaaatc aagtactaag gctacctata catctatccc aactacagaa caagtaaaaa
    15481 aagactttaa ctttacccct aatatagttt ctgaatttag taatggatat aaatttaaag
    15541 gagcatatac tgtaaataaa aaagcatttg acaaagaaaa taatgtttta ggaaaatcaa
    15601 aagcacttag ttttgaatat aaaaatggca atgatgaaat atctcttgac acagcaaata
    15661 atgtacttgg gaagagttct gacaatctaa aagttgtaga tacttacaaa gatattaata
    15721 tttcttatga agcattcgca caaaagttta taccagaagg ttataaaatg acagaacagg
    15781 ataaaattga tgaaaaatca ggcaaataca catttagtgt ggggccaaat aatgaatcag
    15841 acaaagttga agttaatgaa tttaagtttt tgacatggaa acaagatgga gtttactatt
    15901 cttttacagt tcaagactca aatttatcta tgaatgactt agttaaaatg gctcatgaag
    15961 taatagatgc aaaataaaca taagtaataa taagttgttt atgagtttat tatttatgac
    16021 tttaattttt ttattagtaa acatggttgt atcttccatc tttatatttt ctttaaattt
    16081 aatatataaa attttagata tttagctacc ttcaaaagaa gcattattaa aaagccctta
    16141 aaaatatttc ttttatatgg aattttaagg gctttaactt tattttatac aagtgtatat
    16201 ggaattttaa agactttaac tttattttat ataagtgtaa gctccatttg aattacttct
    16261 tcttttacag gtctatcatt ccatgtaaaa ccactagata ttgtatttac ctctacaaac
    16321 cctaaagatt tataaacatg aatagctcta ctattacttt taaatacatc aagctcaatt
    16381 ttttcatacc catattcttt tgataaatca ataatttgtt ttaaaagact acttccgata
    16441 cctttttccc tatactcttt aagaataccc atgcctaaat aaccaacttt ttcagtttta
    16501 ggtaaaacgt cacaccaacc aatacagtta tctgattcta aatcaattat aaacagttgt
    16561 ggtaagtttt tatttataat attttttata aattcaactg tttcttcaaa aggaaaggct
    16621 tcatccatag ctagatattt cctctctttt gctattttat caaaagtttg ccaatacgaa
    16681 taaatatact tttcttctgc ctttataaat tttatgcctt ctatcaactt aacatttccc
    16741 ctttttaatt tttgattgta gttaacttat tttatatgat tctagtttat aatgctatat
    16801 aaattactat atattagctt aaaatatctt tgtatatttc tataaaatta aaaccaatat
    16861 atctatctct tgcatctcta ttaaaataat ttttaatagt ataataaata tagttcttta
    16921 atcttttggg tatatatact taatcatttt gaaatttgat ttaaagtata ataaaatata
    16981 taaaaaaata tataaaatgg tactataaaa tttttaatct tcatcaatac cttttttgct
    17041 ttcattgtta aaactatttt ttctattagt ttatttctta taaaacaaac atttagtatt
    17101 aaaatatata tcacacaata gtatttgcaa tttaacttta aaaaaataaa aatacccaac
    17161 tgacctaagc aactcgattg ggtataaata atctaaaaaa tcatttttgt ataaactctt
    17221 tatttaactt acatttttat ttaccttcta ctttaattca acttatattt ctatgcttct
    17281 tatactctca ttcaacttat atttctactt atcttatact tttataaatt catcacaatt
    17341 atttagttct cgctatcaaa gaaattgtat taaaatactt tccattctct acttccatca
    17401 tttttttgtc atttatagca tatgaattat cacaatttat ccaatccttc caagcttcat
    17461 catgacaatt taaagcttca catttctcta caatcacaga ctccgattca gaccaaagtt
    17521 tattccacca tgtaattgaa tggaagttca tattatcttg ccaaaatgga atgagttcat
    17581 ctggtataca atccacgaaa tcttctttta atccaggcat tgccatagca agtattcccc
    17641 cctcttttac aagaggtgat atatgattgt ctaaaaatcc ttctttgttt ccaaaatagt
    17701 gataagaatc gatacttatc accgcatcaa agaaaccttc tgcataaggt agttcatgtg
    17761 cctctgcctg tattggaaat attttatcat ccaatttaaa ctctttaaat cttttatagt
    17821 tttcagttgg ttctatccat aaatctgttg caaatacagt agcatcaaat tcctttgcta
    17881 aaaatatcga agatataccc ttaccacaac ctaagtctaa aatacgcatt cccttttcta
    17941 gttttatctt acttgttaat tcttccaata tttttataca attaggtccc atcatatttt
    18001 tcatgagaaa gtccttatcg tatttattac tttttgtaaa tatcattcta tctttccttt
    18061 ccctatcagt tattatttat taaattttat acgtttgatt ttttattttt tatctgcttc
    18121 ttatattgag caatctcttt tttattcatt ctttaacaga caattttaat gtgtaatttt
    18181 atccactctg tgatagtaac tttaatgaat aatcttatct actgtgatag ttattttagt
    18241 gagtaatttt atctactcca cagcaatcgc tttaatgagt aatcttatcc actctatgat
    18301 agttatttta gtgagtaatt ttatctactc cacagtaatc gctttaacga gtaatcttat
    18361 ctactctata atagtcactt taatgagtaa tcataatttt tatatcattt tagatactta
    18421 ctctaataag aattcatttt ctaatactta ataagtttta attacttcca ctttaaccta
    18481 tatactaatt aacttattta atttagtgca tatttgacac tttacctttt attataccat
    18541 t
//
LOCUS       DAYAOO010000082        18271 bp    DNA     linear   BCT 12-OCT-2024
DEFINITION  TPA_asm: Clostridioides difficile isolate ST8-SSI-h139-18
            SAMN40601845-rid21577343.denovo.082, whole genome shotgun sequence.
ACCESSION   DAYAOO010000082 DAYAOO010000000
VERSION     DAYAOO010000082.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN40601845
            Sequence Read Archive: SRR28438827
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 18271)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 18271)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-MAY-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-MAY-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002157583.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002157583.1
            Genome Coverage       :: 163x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/11/2024 16:19:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 4,038
            CDSs (total)                      :: 3,963
            Genes (coding)                    :: 3,930
            CDSs (with protein)               :: 3,930
            Genes (RNA)                       :: 75
            rRNAs                             :: 6, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 60
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 33
            CDSs (without protein)            :: 33
            Pseudo Genes (ambiguous residues) :: 0 of 33
            Pseudo Genes (frameshifted)       :: 7 of 33
            Pseudo Genes (incomplete)         :: 25 of 33
            Pseudo Genes (internal stop)      :: 11 of 33
            Pseudo Genes (multiple problems)  :: 8 of 33
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..18271
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN40601845-rid21577343.denovo.082"
                     /isolate="ST8-SSI-h139-18"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Denmark"
                     /collection_date="2018"
                     /collected_by="Statens Serum Institute"
     gene            563..1423
                     /locus_tag="ACGI5H_003032"
     CDS             563..1423
                     /locus_tag="ACGI5H_003032"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891460.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HFG9698728.1"
                     /translation="MKIIQILNNNVALVKRGKNEIIVFVKGIGFKKRVGQVINENEIE
                     RTYILDSYDMLEHFSYLLQNSDSNNIVLINEIIEYGEKTLNIKASDYLSLTLLDHLEF
                     LLKRCKKNQFIKSPLVWNVKRFYPKHFEIGMHALKLIGDSKGINLPDDEAVSIALHFV
                     NMEVNKESHDSTIVELRTLADIVSIIKYHFNVELDETSTNYMRFTTHLQYFIQRIMSE
                     EASIDEDNSIDLYKQVSQLYPKSFGSVQKIRKYIKSQFNVDISISEETYLMLHINRVT
                     QRLEAKSDEI"
     gene            1413..3284
                     /locus_tag="ACGI5H_003033"
     CDS             1413..3284
                     /locus_tag="ACGI5H_003033"
                     /EC_number="2.7.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427323.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_function: GO:0015573 - beta-glucoside transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA];
                     GO_process: GO:0015759 - beta-glucoside transport
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="beta-glucoside-specific PTS transporter subunit
                     IIABC"
                     /protein_id="HFG9698729.1"
                     /translation="MKYKDLNENIIKLIGGKENIKSVAHCVTRLRFTLNDRSIAQTEE
                     IKKLKGVIDVVSNDVAYQIIIGTHVVDVYNEFMSMIGLSSSESSIKSERKKGIRGIKG
                     IFNSIFVVVSETMTSVIEVLLAAGILASILALLNMSGILQSDSPTYQILDTLRSATFH
                     FLPVLIAIASAKRLNVNPYIAVVLAVTLLSSSIDGVEGLSLFGINLQSTTYANSFIPI
                     LLGVWAMGIIIEGLKKILPKALHYFLVPVLSLIITLSVTLTVFGPIGMWIGDGLNYAC
                     MFLIDTLGNWSVVALYAALQPLLIVFGAANFTMPISLNSVTTLGYDPIFMGAATISDI
                     AVCGAMFGYFLKTRNKEQKQLFGTVSFSALMGVTEPSVFGVFMKYRRPFVAVMIGGGI
                     GGLIAGLAQVKTYGMVWGLAALPTYLVGGEVSNFTFMIISVVVSFVAATAASYLLGIP
                     SDEKEEVKGDNEKELELIINENNSRTISIGNVAKGQVIALGEVNDKAFSSGALGKGVG
                     VIPSESKSTVISPVDGTITIVFPTKHAYGIVTDEGLEILIHIGIDTVNLDGKFFESLV
                     TQNQRVKKGDALAVFESDKIIEEGFDSTIITVVTNTSDYLDVISSNDESEELLTVIV"
     gene            3304..4758
                     /locus_tag="ACGI5H_003034"
     CDS             3304..4758
                     /locus_tag="ACGI5H_003034"
                     /EC_number="3.2.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003440025.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016798 - hydrolase activity, acting on
                     glycosyl bonds [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
                     /protein_id="HFG9698730.1"
                     /translation="MNIKDTFFWGGSIAAHQCEGSWDSDNKGPAIMDFVTKGSYEMPR
                     VITDKIEEKLDYPSHNGIDFYNRYKEDIALFKEMGFSALRISIDWSRIFPNGDDENPN
                     ELGIKYYEGLIDTLIENNIEPIVTLYHFELPMNLVHKYGSWNNRKLIDLYLKYSETVI
                     RRFDDKVKYWVTFNEMNHIDPQTEHSDIFTYMIAGIKYSEIENKVQTLANVGYNMTLA
                     GVKVAKLAREINPNNKVGCVFGLNPIYPYNCNPSNVLNAFLDNDRDYYQIDAMCNGKF
                     PQYKLKEYEKNNITIEVTDEDKKAFKEGKLDFIGLNYYFSSVSTPKENLSGDKSLFGG
                     IQNPYLEQSKWGWAIDPIGLRFTLNYIYRKYQLPILITENGLGAYDKIEEDGTINDDY
                     RIEYLGKHLSQMKSAIEEDNVECFGYLMWGPIDLVSATTGQMSKRYGFIYVDLDDEGK
                     GSFKRYKKKSFDWYKEVIKSNGEVLDFSTDIVVG"
     gene            5783..6991
                     /locus_tag="ACGI5H_003035"
     CDS             5783..6991
                     /locus_tag="ACGI5H_003035"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422412.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9698731.1"
                     /translation="MENFWNPLTCFTVCVMIYAFSEFLSKKTKGAISTLLFVCIIFLL
                     GFWTNILPKDITGASGILAAMSNFGIALLITNLGTLINLEDLCHEWKTVVIALVGIVG
                     IGVGCLTVGSMLFGREYALIAAPPIAGSTVAGIIVTTVAEAANRPELAAFVILVLSFQ
                     KFFGIPITTYCINKELKFKRDNGDFLKDESKSNFKLPSMRIFKEDLGKKSSTLVYLAK
                     LSFVAMIGNFVGLATLIPGFTPANYYLNPNIACLLVGLIFTRIGFLEKGILDKSQSNG
                     IIMFGCMLMLPGGLAKVTPTALFGMIVPTIGILVVGSVFIILFTAIVGKLLGYSPRMS
                     AAIGVTCMLAYPATQIISNEGIDAMEGTEEEKQRATDYLLPKMIIGGFVTVTIASVAF
                     ASIIGPIIFG"
     gene            7022..8401
                     /locus_tag="ACGI5H_003036"
     CDS             7022..8401
                     /locus_tag="ACGI5H_003036"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422413.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M20 family metallopeptidase"
                     /protein_id="HFG9698732.1"
                     /translation="MIGSISINEIDKKRFKLDDLSKKIWENPEKAFKEFKACENTANF
                     LRSEGFDVEVGVGGLATAIRASFGSGKPVIGFMGEFDALPGLNQKVSTKQEAFELGAY
                     GHGCGHNLLCTAHVGAVVGLKREMIENNLSGTIVFYACPGEEQLTGKGFMARGGAFEG
                     LDLAINFHPNKISEATIGTSTAVNSVKFHFKGKTAHAGSDPQNGRSALDAVELTNVGA
                     NYLREHVTSDVRIHYTITDGGVAPNIVPDKASVWYYTRALSREAVESTYERLVKVAKG
                     AAMMTETEVEVEFLGGCYNTLNNHVLANLVSECMNEIKQEPWTREELDFAAELDRQSP
                     QQYKAMISKYNLPEGTHLYYGGGNVTNFNSYGSTDIGDVMHIVPTAYFFTGCTNLGAP
                     GHSWQFTSCAGSSIGEKGMIYASKIMAMFGAKILNNPEIAKKAKEEFDKSMNGKTYKC
                     PIPDDIPTP"
     gene            8507..9697
                     /locus_tag="ACGI5H_003037"
     CDS             8507..9697
                     /locus_tag="ACGI5H_003037"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861827.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M20 family metallopeptidase"
                     /protein_id="HFG9698733.1"
                     /translation="MKNFFKEAQSIEGEIIRWRRYLHENPEIGCNLPKTVTFVTSTLE
                     KMGYSPKLTSNNGIVAVLDSENGGKTLLLRADMDALPIREETDLPFKSKNKDASHSCG
                     HDNHTAMLLGAAKILMDNKHLLKGRVKFVFEPDEETTRGAKSMIDDGILENPQVDAAM
                     AFHSMVGKFLNTGQVAYSRGPAMASADIFEITVEGKATHGASPEFGVDPINIMSHIQI
                     ALNTILSREKPQKEPVVLTIGMFNAGNVPNAIPNKASMSGTLRTFDQFVREKLKNRII
                     EISTGIAKSFGGNAKVEFKMGTPAVINDLDVGDEIVSYVKEVIGNENVIDFPSAMGSE
                     DFSEVLLRVPGVFLWIGMGSISQGYNFGMHNPKAIFNEEGLVYGSALFAHCAVKWLEN
                     NFSR"
     gene            complement(9825..11153)
                     /locus_tag="ACGI5H_003038"
     CDS             complement(9825..11153)
                     /locus_tag="ACGI5H_003038"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422415.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9698734.1"
                     /translation="MMKIAVITTEFLKEFVDNSIKKLNINAEIEIYIYRDFSHVGDLY
                     LEIEDRFDGFAVSGPIPKKAITKKAGTIKKPLVDFGTDLQSYYDMFLKLIFKYNTLDF
                     SRAYFDLTDWADNPKDISYYLSNGTFGDLMDSIDENASKMSLSDIAKLEKKIAKKHIN
                     LWNEGKIDFSTTRFSSIVPMLQNAGVNFHFIYPDIDLLKNTFNNLIKDIHLHRMKGNQ
                     PSVIYITVKDTNYDDSTLDQVYKILNSIKKDKLTDFIIEKNSNSFKIFTKCETIKSLT
                     KNFTACYIKESIENSTNIKVCIGYGIGNDIKQAMSSAISANKESKINPLNYSFLVNEN
                     YETIGPLLCDKLLTVSNKVTPHINTIAKSSKLSTLTIQKIISVTEILQRDEVTPKELS
                     SCLNVTVRTANRFLSSLLKSGNATILYEKQNSTKGRPERVYKLFISENKY"
     gene            complement(11771..12985)
                     /locus_tag="ACGI5H_003039"
     CDS             complement(11771..12985)
                     /locus_tag="ACGI5H_003039"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891452.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phosphofructokinase"
                     /protein_id="HFG9698735.1"
                     /translation="MRNCIIAQSGGPTAVINASAVGIYEKNLETKYFDKVYFGINGIE
                     GILNKNIIDSDSLNKDNVLNLKQTPSSGLGSCRYKLADYKINSYDYDRVINILDEYKI
                     DTLFYIGGNDSMDTVMKFSQYCKNTTCKIKFIGIPKTIDNDLLGTDNCPGFGSAAKLI
                     STLIMETYLDFSIYKNNGIFIVETMGRDTGWLAASSSLARLNDTPLVDLIYLPEIDFY
                     EDKFIEDVRKIFKEKNKAYIVASEGIRDKYGNFICEQKTSAHDKFGHSQLGGVSNYLK
                     NLIVSSSITTRVKTLELGVIQRCAMHLASDTDLKQAAEVGAYGIELSKKGYTGVMAII
                     NRTCNNPYKYEVSHTDISKIANKTKYFPKEWINEECNYITDEALNYLYPLIQGKPDIK
                     YKNGLPYFSIIY"
     gene            13411..14127
                     /locus_tag="ACGI5H_003040"
     CDS             13411..14127
                     /locus_tag="ACGI5H_003040"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422419.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004750 - D-ribulose-phosphate 3-epimerase
                     activity [Evidence IEA];
                     GO_function: GO:0016857 - racemase and epimerase activity,
                     acting on carbohydrates and derivatives [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA];
                     GO_process: GO:0006098 - pentose-phosphate shunt [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribulose-phosphate 3-epimerase"
                     /protein_id="HFG9698736.1"
                     /translation="MKHIKIAAGLAHVNYGHISAVVKEAMDAGVDYVHSDAADMHDLK
                     NMQLMGGHQIIEAIRPVTDKPIECHIYTRDCDRLFIEKIAAAGCNLLIIPAEHFLGAP
                     LAYIINYCREFGMKVGLTIGCYTPLCFVDEAIYDIDRLQIVVHGVDETDGKDNWGWRK
                     SAVDLVKRARKMIDEKNPKCELAIDGGLRADNMEPLIECNPDVVILSSAIFKDKDGIT
                     AGVKNCRKAIDEAATKFGLE"
     gene            14262..14888
                     /locus_tag="ACGI5H_003041"
     CDS             14262..14888
                     /locus_tag="ACGI5H_003041"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427309.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HFG9698737.1"
                     /translation="MKKEMIKDYLLITISAFLMALAVNFFFAEHTLAPGGITGLSVVL
                     STFLSMPVENISLGISMPLLVMGLLFLGKGFGIKTLYITLMGPLFLKVIPQTHITDNL
                     LVAGVIGGLLVGTAIGIAIIRGCSTGGTDLVAMLINKVIKFLKLPVILFMLDGFIIVA
                     SGIISKNFMISIYSLISLLLIIKTIGFVTTKFGKNTEEINNINNACAQ"
     gene            complement(15088..16632)
                     /locus_tag="ACGI5H_003042"
     CDS             complement(15088..16632)
                     /locus_tag="ACGI5H_003042"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422422.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antiterminator"
                     /protein_id="HFG9698738.1"
                     /translation="MNKRLLDIAELLLNSSDYITVDTIAEELKVSNKTIRNDLVILDE
                     WLLEFNLSLDKKTGSGVIILGNEDIKLKVIRDINDKSNCIYAYSPEDRKRYILSKLFI
                     KNSKFRIRDICNELHVSRATVHKDLVVIQNFLQNFKVTLVRKTNNGVYLEGKEKDIRK
                     AIFELATVNKSYTELKEILFSKSNECKDTPSTKIFKELFNYDFEKLSQITLHTLQVEK
                     SNLSDEYYINFLIHIAICIKRISIKRYINLSEGFFRELLEHEYFEKSKILCANLSEAF
                     DVEFIDEEVCYILLHIEGLLKSIKKTTTLEPLKNEEITEYNLSEAIAVHWGSILNLNL
                     KDDLILIKSLANHLKSVLHRINYGFTITNPILNDIKRTFPYTYKAAKESNTVIKQLMN
                     YEVNDDEIGYLALYLISAIDRSKSPLNTILICHCSDGVSNLLVQKLSFEFNQINIVKS
                     IPLSSISFTNFDDVDLILTTAPVDFEHNAELININALLSKNDISRLSTIIKKLYSEKN
                     KILSYK"
     gene            complement(16658..17299)
                     /locus_tag="ACGI5H_003043"
     CDS             complement(16658..17299)
                     /locus_tag="ACGI5H_003043"
                     /EC_number="2.2.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427306.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transaldolase family protein"
                     /protein_id="HFG9698739.1"
                     /translation="MKYLIDSANLDEIQKCLKYGFKGITANPSMYLKEKVNFHEFIET
                     CANLNPEILTAEVIGNNLYELINSCDKILNINKNTIIKINFSEVGLELINILNSKGVK
                     TACTLIFNVNQASLAINAGADYLFPFIGRNDENGNDGIKNLTEICNLISINGYNTKVV
                     AASIKNVFHLTQASLCGCDYAAVTYDLFKKASFNQLTIDGANTFERDWSKVNK"
     gene            17569..17763
                     /locus_tag="ACGI5H_003044"
     CDS             17569..17763
                     /locus_tag="ACGI5H_003044"
                     /EC_number="1.1.1.1"
                     /inference="COORDINATES: protein motif:HMM:NF012678.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="iron-containing alcohol dehydrogenase"
                     /protein_id="HFG9698740.1"
                     /translation="MINFYQPSRINFGQGTLSELPRIIGKYGKKCLLVTTPNVEPLDK
                     LYKRVTLNLIEKGIEVVHFD"
BASE COUNT         6768 a         2156 c         3026 g         6321 t
ORIGIN      
        1 tatatattag tatatcttac tagcatttaa atgaaactaa atttaagtat ttatatatta
       61 gtatatctta ctagcattta aatgaaacta aatttgaagc tttacctatt aatatatctt
      121 aatagtgatt aaataaaact aaacttaaga ctttatatgt taatatatct taagaattta
      181 tttgttaaaa tacagttcat tatatttaaa agcattacta tgataattca taatagtaaa
      241 atagataatg gttcagacaa tattataaat actagtgacg gtaaaatagt atcaatttag
      301 tatataaacc ttgtcagata atcgcataac agagcttgta gttatagaat aaaaaaatat
      361 ctaggaaacc gttgacagat ttatatggat agtataacat atagaatatg aaattaaaca
      421 aaaaagaatt ttaattatgg cgacgtagtc ataattttga gtatgttact gattagcagg
      481 cagaactcaa gtatatatgt gaaaaataga gggatactct atacatatat gcttgagttc
      541 tttttattga agggaggaat atatgaaaat aattcagatt ttaaataata atgtagcctt
      601 agtaaaaaga ggtaaaaatg aaattattgt atttgttaaa ggaattggct ttaaaaaaag
      661 agtgggacaa gtaataaatg aaaatgaaat agagagaaca tatatactag attcatacga
      721 tatgctagaa cactttagtt atctactaca aaactcagac tccaataata tagttcttat
      781 taatgaaata attgaatatg gtgagaaaac tttaaatata aaggcaagtg attatctaag
      841 cttaacctta ctagaccatt tagagttttt acttaaaaga tgtaaaaaga atcaatttat
      901 aaaaagtcct ttggtatgga atgttaaaag attttatcca aagcattttg aaattggaat
      961 gcatgcacta aaattaattg gtgatagtaa gggaattaat cttcctgatg atgaggcagt
     1021 atcaatagca cttcattttg taaatatgga ggtaaataaa gagtctcatg atagtacaat
     1081 tgtagagttg agaactttag cagatatagt ttctataata aaatatcatt ttaatgtaga
     1141 gctagatgaa acttcaacaa attatatgag atttactact catctacagt actttatcca
     1201 aagaattatg tcagaggaag cttcaataga tgaagataat tctatagatt tatataaaca
     1261 agtaagtcaa ctttatccaa agtcatttgg aagtgttcaa aagataagaa aatatataaa
     1321 atcacaattt aatgtcgata tatctataag tgaagaaact tatttaatgt tgcatataaa
     1381 tagggtgact caaagactgg aggcaaaatc agatgaaata taaagattta aatgaaaata
     1441 taataaaact tataggggga aaagaaaata taaagtcggt agcgcattgt gttactcgtt
     1501 taagatttac tttaaatgat aggagtatcg ctcaaacaga agaaattaaa aaattaaaag
     1561 gagtaattga tgtagtttct aatgatgttg cttatcaaat tataataggt actcatgttg
     1621 tagatgtata taacgagttt atgtctatga taggtttaag ttcaagtgaa tcaagtataa
     1681 aaagtgaaag aaaaaaggga attagaggta tcaaaggtat atttaattcc atctttgtgg
     1741 tagtctcaga gactatgact tcagtaattg aagtactact tgcagctggt atacttgcaa
     1801 gtatattagc acttttaaat atgtctggca tacttcagag tgacagtcct acatatcaaa
     1861 tattagatac attaagaagt gctacatttc acttcttacc agtattaatt gcaatagcat
     1921 cagcaaaaag acttaatgta aatccatata tagcagtagt attagcagtt acgttattat
     1981 cttcatcaat agatggtgta gaaggattaa gtttatttgg tataaattta cagtctacaa
     2041 cttatgcaaa cagttttatt ccaatacttt taggagtatg ggcaatggga attataattg
     2101 aaggtttgaa aaaaatatta cctaaagcac tacactattt tttagttcca gtattatctt
     2161 taataataac tctatcagtt acattaactg tatttggacc tattggtatg tggattggtg
     2221 atggattaaa ctatgcatgt atgtttttaa ttgatacatt gggtaattgg agtgttgttg
     2281 cactgtatgc agctttacaa ccactcttaa tagtctttgg tgcagcaaac tttactatgc
     2341 ctatatcttt aaattctgtg acaacattgg ggtatgaccc aatttttatg ggcgctgcaa
     2401 caatatctga tattgcagtt tgtggtgcaa tgtttggata tttcttaaaa actaggaata
     2461 aagaacaaaa acaattattt ggtacagtaa gttttagtgc acttatggga gttacagaac
     2521 cttcagtgtt tggtgtgttt atgaaatata gaagaccatt tgtagcagta atgataggtg
     2581 gaggtatagg tggtttaata gcaggtttag ctcaagttaa aacatatgga atggtttggg
     2641 gattagctgc attaccaacg tatcttgttg gaggagaggt atctaacttt acatttatga
     2701 taataagtgt agtagtatca tttgtagcag caacagcagc ttcctattta ctaggaatac
     2761 cttcagatga aaaagaagaa gttaagggtg ataatgaaaa agaattagaa ctaataatca
     2821 acgagaacaa ttcaagaact attagtattg gaaatgttgc aaaaggtcag gtaattgcac
     2881 ttggggaagt taatgacaaa gcattttcct ctggagcatt aggtaaaggg gttggagtta
     2941 tacctagtga atcaaaatca actgttatat ctcctgtaga tggaactata actatagtat
     3001 ttccaactaa acatgcatat ggtatagtga ctgatgaagg attagaaata ttaattcata
     3061 ttgggataga tactgtaaac ttagatggaa aattctttga aagtcttgta acacaaaatc
     3121 aaagggttaa aaaaggagat gctttagcag tatttgaatc tgataaaatt atagaggaag
     3181 gctttgattc tactataata actgtagtta caaatactag cgattattta gatgtaatct
     3241 catcaaatga tgaatcagaa gaattattaa ctgtaatagt ataaatttta ggagggaaaa
     3301 ttcatgaata ttaaagatac atttttctgg ggaggaagta ttgcagccca tcaatgtgaa
     3361 ggttcatggg atagtgacaa caaaggacct gcaattatgg attttgtaac taagggctct
     3421 tatgaaatgc caagagtaat tactgataaa atagaagaaa aattggatta tccatctcat
     3481 aatggaatag atttttataa tagatataaa gaagatatag ctttatttaa agaaatggga
     3541 tttagtgcat taagaatatc tatagattgg tcaagaattt ttccaaatgg agatgatgaa
     3601 aatcctaatg aattagggat taaatactat gaaggtctga tagatacatt aatagaaaat
     3661 aatatagaac ctattgtaac actatatcat tttgaattac ctatgaattt agtacataaa
     3721 tatggttcat ggaataacag aaaacttata gatttgtatt taaagtacag tgagactgta
     3781 ataagaagat ttgatgataa ggtaaagtac tgggttacat ttaatgagat gaaccatatt
     3841 gaccctcaaa cagagcactc ggatattttt acttatatga tagcaggtat taagtatagt
     3901 gaaatagaaa ataaggttca aacattggca aatgtagggt ataatatgac tttggcgggt
     3961 gtaaaggttg caaagttggc tagagaaatc aatcccaaca ataaagttgg atgtgtattt
     4021 ggactaaatc caatttatcc atacaattgt aatcctagta atgtgttaaa tgcattttta
     4081 gataatgacc gtgattatta tcaaattgat gcaatgtgca atgggaagtt tccacaatat
     4141 aaattaaaag aatatgaaaa aaataatata actattgaag tgactgatga agacaaaaaa
     4201 gcatttaaag aaggtaagtt agattttata ggacttaatt attatttttc aagtgtatct
     4261 actccaaaag aaaatttatc aggtgataaa tctttatttg gtgggattca aaatccatat
     4321 ttggaacaaa gtaagtgggg gtgggcaata gaccctatag gtttaagatt taccttgaac
     4381 tatatttaca gaaagtatca attacctatc ttaattacag aaaatggttt aggggcatat
     4441 gataaaatcg aagaagatgg aactataaat gatgattata gaattgaata tttaggtaag
     4501 catctatctc aaatgaagtc tgcaattgaa gaagataatg ttgaatgttt tggatatttg
     4561 atgtggggac caattgattt agtcagtgca actacaggtc agatgagtaa gagatatgga
     4621 tttatctatg ttgacttaga tgatgaaggc aaaggaagtt ttaagagata taagaaaaaa
     4681 tcatttgatt ggtacaaaga agtaataaaa tctaatggag aagttttaga tttttctacg
     4741 gatatagtag tagggtagga ataagataaa tagaagttag gaactaatgt taattagtgt
     4801 ctagtaaagc atttaaaata gagtataggg tctttaaagt aaagtgtgta ttcttcttaa
     4861 aagtaatggc aactaaaatt actataaaaa ggagaataca cattttttat gtttatactt
     4921 aagtaaatat ttagacatat tcatagtata atttactcat tatataaaaa tagtatgatt
     4981 tactcactat ataactttat aaattttctg gaaaaatgtc agaatatatt gacaaagaaa
     5041 agatttaaaa ttataatcta tattaagaat agtttgacaa tataaaaaca agtattttta
     5101 taaatagtga aattattttt attgtcaatt taagaataat ttaggactac tataaagata
     5161 aaggtataga tgtcattata tgataaatta tacttgtata gaaagaattt taaagtatgg
     5221 cttatcattg atttaatata ataaataatt tttgtttcta gtaatagttc ctaggaataa
     5281 gatatctaaa ttcgtttaga aatagtctaa tttacaaagg aggggatgca ctaatagata
     5341 aaatttctat ataaagaaga cttaaagtga agtatattct gataatattg gtttaatggg
     5401 tatattatta tttcgtttta gatattttaa gaataattta agacgtttat aaaaatgtat
     5461 tctatatcta atatttaaat aaatataagt cttccaacat gtatactaat atagagagta
     5521 gttgaagtac aattctaact cgtaaaatta tgtagaaagt aaaaatcaaa aagaaatcta
     5581 gtaagttgat aactatagtt aatatttaga gagttaactc tagttatatt tatttagata
     5641 ttttaggaat aatttaggac gtatataata tcatcaaaaa atatcaagct ataccatatg
     5701 tagttaagaa taactgcata atatacattt tataattatt gttttattga taaaaaatta
     5761 ttatatttag gaggaaacaa caatggaaaa tttttggaat ccacttactt gctttactgt
     5821 atgtgtaatg atttatgctt ttagtgagtt tttatctaag aaaacaaaag gtgcaatttc
     5881 aacattgtta tttgtatgta ttatattttt actaggattt tggacaaata ttttaccaaa
     5941 agacattaca ggagcatcag ggatattagc tgcaatgagc aactttggta tagctttatt
     6001 aataactaac ttaggaacac ttataaatct tgaagactta tgtcatgaat ggaaaacggt
     6061 tgtaattgca ttagtaggta ttgtaggaat aggagttggc tgtttaacag tgggtagtat
     6121 gttatttggc agagagtatg ctttaatagc agcacctcca atagcaggtt ctactgttgc
     6181 tgggattatc gtaacaactg ttgcagaagc tgcaaataga cctgaacttg ctgcatttgt
     6241 aattctagta ttatcatttc aaaagttctt tggtattccg ataactacat attgtataaa
     6301 taaagaatta aaatttaaaa gagataacgg ggattttttg aaagatgagt caaaaagtaa
     6361 ttttaaactt ccaagtatga gaatttttaa agaagattta ggtaaaaaat catctactct
     6421 agtgtatctt gcaaagcttt catttgttgc tatgattggt aattttgtag gattggctac
     6481 tttaatacca ggatttaccc ctgcaaacta ttatttaaat cctaatatag catgtttgtt
     6541 agtagggttg atttttacac gaataggttt tttagaaaaa ggaattttag ataaatctca
     6601 atctaatgga attataatgt ttggttgtat gttgatgtta cctggaggac ttgctaaggt
     6661 aactccaaca gcattgtttg ggatgattgt tccaactata ggaatacttg ttgtaggttc
     6721 tgtatttata atattattta ctgcaattgt aggaaaacta ttgggatatt ctccaagaat
     6781 gtcagctgca attggtgtaa cttgtatgct agcttatcct gcaacacaga taatttccaa
     6841 cgaaggtatt gatgctatgg aaggaactga agaagaaaaa caaagggcaa cagattattt
     6901 attaccaaag atgattatag gaggatttgt tactgtaacc attgcatcag tggcatttgc
     6961 tagtataata ggtccaatta tatttggttg atagtaaata tacttatagg aggaatagga
     7021 aatgatagga agtatatcta taaatgagat agataaaaaa agattcaaac ttgatgattt
     7081 aagtaagaaa atatgggaaa atccagaaaa agcatttaaa gaatttaaag catgtgaaaa
     7141 tacagcaaac tttctaagaa gtgaaggatt tgatgtggaa gtaggtgtag gaggtttagc
     7201 cacggctatt agagctagtt ttggttcagg taaaccagtt ataggtttta tgggagaatt
     7261 tgatgcatta cctggtttaa atcaaaaagt ttcaacaaag caagaagcat ttgaattggg
     7321 tgcatatggt catggatgtg ggcataattt attatgtaca gcacatgtag gggcagtagt
     7381 agggcttaaa agagagatga tagaaaataa cttaagtggg actatagtat tttatgcatg
     7441 tccaggagaa gaacaattaa caggtaaagg atttatggct agaggtggag cgtttgaagg
     7501 gttagactta gctataaatt ttcatccaaa taaaattagt gaagctacaa ttggtacttc
     7561 aacagctgtt aactctgtaa agtttcactt taagggaaag actgcacatg cagggtcaga
     7621 ccctcaaaat ggaagaagtg cactagatgc tgtggaactt actaatgtgg gagctaatta
     7681 tttgagagaa catgttactt ctgatgtaag gattcattat acaattacag atggaggagt
     7741 agcacccaac atagttcctg ataaagcatc agtatggtat tatacaagag ctttaagtag
     7801 agaagctgta gaaagtacat atgaaagact tgtaaaggta gcaaaaggag ctgcaatgat
     7861 gactgaaact gaagttgaag tagagttttt aggagggtgt tataatactt taaacaatca
     7921 tgttttagca aatcttgtat cagaatgtat gaatgagatt aaacaagagc cttggactcg
     7981 agaggaattg gattttgcag ctgaattaga tagacaaagc ccacaacaat ataaggctat
     8041 gataagtaaa tataatttgc cagaaggaac tcatctatat tatggtggag gaaatgttac
     8101 aaactttaat agttatggct ctactgatat tggagatgta atgcatatag ttccgacagc
     8161 atactttttt acagggtgta cgaatctagg agcaccaggt catagctggc agtttacatc
     8221 ttgtgcagga agttctatag gagaaaaagg tatgatatat gcatcaaaga ttatggctat
     8281 gtttggagct aaaatattaa ataatccaga gatagctaaa aaggcaaaag aagaatttga
     8341 taaatctatg aatggtaaaa catataaatg tcctattcca gatgatattc caactcctta
     8401 aaaagacatg aaatttaata tataaaatta taatttttat atcagcatca tttcattact
     8461 aaaagaaagt gagattttgc tgactatctg attaggagga aggaatatga aaaatttttt
     8521 taaagaagcg cagtcaatag aaggggaaat tattagatgg agaaggtatt tacatgaaaa
     8581 tcccgaaatt ggttgcaatc taccgaaaac agtaaccttt gttaccagta ctttagaaaa
     8641 aatgggatat tctccgaaat tgacgtctaa taatggaata gtagctgttt tagacagtga
     8701 aaatggtgga aagaccttat tattaagggc agatatggat gcacttccta ttagggagga
     8761 gacggattta ccttttaaaa gtaagaataa agatgcatct catagttgtg gacacgataa
     8821 tcacacagca atgctcttag gagcagctaa aatacttatg gataataagc acttacttaa
     8881 aggtagagta aagtttgtat ttgaaccaga tgaagagact accagaggtg caaaatcaat
     8941 gattgatgat ggtatattag aaaatcctca ggtcgatgca gctatggcat ttcacagtat
     9001 ggtgggtaaa tttcttaaca caggtcaagt agcttattca cgtggtccag ctatggcatc
     9061 tgcggatata tttgaaataa cagtagaagg aaaagcaact catggagcaa gccctgaatt
     9121 tggagtggac ccaataaaca taatgtcgca tatacaaata gcattaaaca ctatactttc
     9181 aagagaaaaa cctcagaaag agcctgtagt tttaactatt ggtatgttta atgcaggaaa
     9241 cgtaccaaat gctataccaa ataaagcatc tatgtcagga actttaagaa catttgacca
     9301 atttgttaga gaaaaattaa aaaatagaat tattgaaata tctacaggaa tagctaaatc
     9361 atttggagga aatgctaaag tggagtttaa aatggggact cctgcagtta taaatgattt
     9421 ggatgtagga gatgagattg tatcttatgt taaagaagtt ataggaaatg aaaatgtaat
     9481 agactttcca tctgcaatgg gttcagaaga tttttcagag gttttactaa gggttccagg
     9541 agtattttta tggattggaa tgggaagtat tagtcaggga tataattttg gtatgcataa
     9601 tcctaaagca atttttaatg aagagggatt agtttatggt tcagctttat ttgctcattg
     9661 tgcagtaaaa tggttagaaa ataattttag tagataataa cataaaatat tattaaatat
     9721 cataaaaggt atatcttaaa aagatgcaaa gatatacctt ttagaaagtc atatataatt
     9781 ttacttaata ttagatgata aaatattttt atgcattttg gattttaata tttattttct
     9841 gatataaata atttgtatac cctttcaggt ctgccttttg ttgagttttg tttttcatat
     9901 aatatagtag cgtttccaga ctttaagaga ctacttagaa atctattagc agttctaact
     9961 gttacattta aacatgaaga taattcctta ggagtaactt catctctttg tagaatttca
    10021 gtaacagata taatcttttg aatagtaaga gtagacaatt tagaactttt ggcaattgta
    10081 tttatatgtg gagttacttt atttgaaaca gtaagtaact tatcacacag taaaggtcct
    10141 attgtctcat aattttcgtt aactaagaaa ctgtaattta aaggatttat tttagattcc
    10201 ttattagcac ttatggcact agacatagct tgctttatat cattaccaat tccatatcca
    10261 atacatactt taatatttgt actattttca atagattctt ttatataaca tgcagtaaaa
    10321 tttttagtta atgatttaat cgtttcacat ttagtgaaaa ttttaaaaga attactattt
    10381 ttttcaatta taaaatcggt taatttatct tttttaatac tatttaatat tttataaact
    10441 tggtctagag tagagtcatc ataatttgta tctttaactg ttatatatat tacacttggt
    10501 tgatttccct tcattctatg taaatgaata tcttttatta agttattaaa agtatttttt
    10561 aataaatcta tatcagggta tatgaaatga aagtttactc ctgcattttg taacatagga
    10621 acaatactac taaaacgagt agtagaaaaa tcgattttcc cttcattcca tagattaata
    10681 tgtttttttg caatcttttt ttcaagtttt gctatgtcag ataaactcat tttagatgca
    10741 ttttcatcaa tactatccat taagtctcca aatgtgccat ttgataaata atatgatata
    10801 tcttttggat tatctgccca gtctgttaag tcaaagtatg ctctggaaaa atctaatgta
    10861 ttatatttaa agataagctt tagaaacata tcatagtaac tttgtaagtc agtaccaaaa
    10921 tcaactagag gttttttaat agttccagcc ttttttgtaa tagctttttt ggggatgggg
    10981 ccactaactg caaatccatc aaacctatct tctatttcta aatataaatc tccaacatga
    11041 gaaaaatctc tatagatata tatttcaatt tctgcattaa tatttaactt ttttatagaa
    11101 ttatctacaa actcttttaa aaattcggtt gttatgactg ctattttcat catagattac
    11161 ttccttttca attattataa ttattttata ttaaatatta cattaatcta ttgttctagt
    11221 taaaatcgta tttcaattaa attcaattaa aataaataac tctttataaa aagcaattat
    11281 ttaggtagag gaatatttgc taactttaat agtctttgtt aactttaatt ttatttaagt
    11341 tattatagtc ttactaattt tataattgta gatttaacta ctttatgttc ttttattgtt
    11401 tatgtagttg atttagaagt tattttaacc atttatttta attgaagttg tttgactttt
    11461 aaatcctttg tgtaatcttt gtttttctag ccatgataaa agtatttcta tttgtatcac
    11521 tatatataat aatatcatga caaaatattt attgtctaac taattataat ctatccaaaa
    11581 tgaaaatggg tgtgagatat tattacaaca aattgtatta gtattaaaaa gattaaaaaa
    11641 ttaaaaaact aaacagttaa ataattaaac gattaagtga ctgtcatata acaatttata
    11701 attttattta acagccactt aggtatttaa gagcgataga attgagtgta tatcaaatta
    11761 taataatttc ctagtaaata attgaaaaat aaggtagtcc atttttatat ttgatatctg
    11821 gtttaccttg aataagtgga tatagataat ttagggcttc atcagttata taattacatt
    11881 cttcatttat ccactcttta ggaaaatatt ttgtcttgtt agctatttta gaaatatcag
    11941 tatgactaac ttcatactta taaggattat tgcatgttct attaatgata gccataactc
    12001 ctgtatatcc ttttttagat agttctatcc catatgcacc aacttcagct gcttgtttta
    12061 aatcagtatc tgaagctaaa tgcatagcac atctttgtat tacaccaagt tctaaggttt
    12121 ttactcttgt tgtaattgat gatgatacta taagattctt tagatagttg cttactccac
    12181 ctaattggga atgaccaaat ttatcatgag cagaagtttt ttgttcgcat ataaagttgc
    12241 cgtatttatc ccttatacct tctgatgcaa ctatataagc cttatttttt tctttaaata
    12301 tttttctaac atcttctata aacttatctt catagaaatc aatttctgga aggtatatta
    12361 aatcaacaag tggagtatca ttaagtctag ctagtgaaga agaagctgct aaccatccag
    12421 tatctctacc catagtttct actataaata taccattatt tttgtatata gaaaaatcta
    12481 agtatgtttc cattattagt gtagaaataa gctttgcagc agaaccaaat ccaggacagt
    12541 tgtcagttcc taataaatca ttatctattg ttttaggaat acctataaat tttattttac
    12601 aagtagtgtt tttgcagtat tgagaaaatt tcatcactgt gtccatagaa tcatttccgc
    12661 ctatataaaa taatgtatct attttatatt catctagtat atttataact ctatcataat
    12721 cataagaatt tattttataa tcagccagtt tgtatctaca agaaccaaga ccagacgaag
    12781 gtgtttgctt taaatttaat acattatctt tgtttaagga gtctgaatct attatatttt
    12841 tgtttaatat accttcaatc ccattgatac caaaatatac tttatcaaag tatttagttt
    12901 ctaaattttt ttcataaata ccaactgcag aagcattgat aacagctgta gggcctccag
    12961 attgggcaat aatacagttt ctcattttac atctcccttt cattaatatt gttatgaatg
    13021 gtacttttta tcgagtaaat ttatatttat agtctgatta tatattaaat gaactagcta
    13081 tatcaattga gttagtatag acaataaatg ccataagaat gtggtaaaaa actaactttt
    13141 tatatacaat taatgtctat aatttaccac aatataaagg tacttttaag gagtagtcaa
    13201 agtgttgtga aaaaaaatat atcagtgtaa tattaattta caaagcaaaa taagttcaca
    13261 gttaacaaaa gcagaataag ttcataaaag aaatatatac agcaataaaa gtaatgctaa
    13321 ataaaagtaa tactggatta aaaaatatta aaaaaatatt aaaaactaat atttaatact
    13381 aattaaagta aaatatggag gtatacaaat atgaaacaca taaaaatagc agcaggatta
    13441 gcacatgtaa attacggtca tatatcagcc gtagttaaag aagcaatgga tgcaggtgta
    13501 gactacgtac attcagatgc agcagatatg catgacttaa aaaatatgca acttatgggt
    13561 ggtcatcaaa taatagaagc aataagaccg gtgacagata aaccaataga atgccatata
    13621 tacacaagag attgtgatag attatttata gaaaaaatag cagcagcagg atgtaacttg
    13681 ttgataatac cagcagaaca ttttttaggt gctcctcttg catacataat aaattactgt
    13741 agagaatttg gtatgaaagt aggattaaca attggatgtt acacaccact atgttttgtt
    13801 gatgaagcta tatatgatat agatagattg caaatagtcg ttcatggtgt tgatgaaact
    13861 gatggaaaag ataactgggg atggagaaag agtgctgttg atttagtaaa aagagctaga
    13921 aaaatgatag acgaaaagaa tcctaagtgt gaattagcaa tagatggtgg actaagagca
    13981 gacaatatgg agccattaat agaatgtaat ccagacgttg taatattatc ttcagcaata
    14041 ttcaaggata aagatggtat aacagcaggt gttaagaatt gtagaaaagc tatagatgaa
    14101 gcagctacaa agtttggttt agaataagat aataaactat gataaaagag atgctttctt
    14161 aatgttttaa ggaagcatta attttatgaa aaactacagg aagctagact aatttaattg
    14221 attttttata ctgaaacaat ataatcatag gaggttatta aatgaaaaaa gaaatgataa
    14281 aagattattt actgataaca atatcagcat ttttaatggc attagcagtt aattttttct
    14341 ttgcagaaca tacattagct ccaggaggga taacaggatt atcagtcgta cttagcacat
    14401 tcttatcaat gcctgttgag aatatatcat taggaatatc tatgccactt ttagtaatgg
    14461 gattattatt tttagggaaa ggttttggaa taaaaacatt atatataact cttatgggcc
    14521 cattattctt aaaagtaata ccacaaactc acataactga caatctatta gtagcaggag
    14581 tgataggtgg gttattggta ggaactgcta tagggatagc aataataagg ggctgtagta
    14641 ctggtggaac tgatttagtt gcaatgctta ttaataaggt aattaagttt ctgaagttgc
    14701 cagttatatt atttatgcta gatggattta taatagtagc gtctggaata ataagtaaga
    14761 attttatgat atctatatat tcattgatat ctttattact cataataaaa acaataggat
    14821 ttgtaactac aaagtttggt aagaatactg aagaaattaa taatataaat aatgcttgtg
    14881 ctcaataaaa ataataaaat ttactttaaa tataaaagtt taaaaaatat aaaagcttaa
    14941 ataaaaagat taaatataaa aaatgaaggt gtctcaaaat gaatttttta gttcatgagg
    15001 cactttttct atgaaatcaa atatattttt atcatttgga caatgaaaaa taggtttatc
    15061 tctatgttga gacaagccta tttttgttta tttataagat aatattttat ttttttcaga
    15121 atatagtttt tttataattg tactaagtct agaaatatca ttcttactta aaagagcatt
    15181 tatatttatc agttcagcat tatgttcaaa gtctacagga gcagtggtta gtattaagtc
    15241 cacatcatca aagttcgtaa atgaaataga agatagaggt atagatttaa ctatattaat
    15301 ctgattaaat tcaaaactta acttttggac taataaatta gatacaccat cactacagtg
    15361 acatattaaa atagtattta ggggagattt gcttctatct attgctgata ttaaatataa
    15421 agcaagatat cctatttcgt catcattgac ttcataattc atcaactgtt tgataacagt
    15481 attagactct ttagcagcct tataagtgta aggaaatgtt ctctttatat catttaatat
    15541 gggatttgta atagtaaacc catagtttat tctgtgtaga actgatttaa ggtgattagc
    15601 aagagacttt attaatatta aatcatcctt taagtttaaa tttagtatac ttccccaatg
    15661 aacagctatt gcttcagata gattatactc tgtaatttct tcatttttaa gaggttcaag
    15721 agtagtagtt ttctttattg atttaagtaa tccttctata tgaagaagga tataacagac
    15781 ctcttcatca ataaattcta cgtcaaaagc ttcacttagg ttagcacata aaatttttga
    15841 tttttcaaag tattcatgtt ctaataattc tctaaaaaaa ccttcagata agttaatata
    15901 tcttttaatt gaaattcttt taatacatat agctatatgt attaagaagt ttatataata
    15961 ctcatcacta aggttacttt tttctacttg taaggtgtgt agagtgattt gagataattt
    16021 ctcaaaatca tagttaaata gctccttaaa tatttttgtt gatggggtat ctttgcattc
    16081 attagatttc gagaataata tttctttaag ttcagtataa cttttattaa ccgtagcaag
    16141 ttcaaaaatt gcttttcgaa tatctttctc ttttccctct aaatatactc cattattggt
    16201 ttttctaact agagtcactt taaagttttg caaaaaattt tgaataacta ccaagtcttt
    16261 atgcacagta gctctactaa catgtagttc attgcaaata tcacgaatcc taaacttaga
    16321 atttttaata aataatttac ttagaatata cctttttcta tcttcaggag agtatgcata
    16381 tatacaattt gatttatcat tgatatctct aataacttta agttttatat cttcattacc
    16441 tagaataata acccctgaac cagttttttt atctagggat aaattaaact ctaaaagcca
    16501 ttcatctaaa ataacaaggt cattacgaat agttttatta ctaactttta attcttcggc
    16561 aatagtatct acagtaatat agtctgagct gttgagtaat aattcagcaa tatctaataa
    16621 tcttttgttc aatgcaaacc ctcctaaatc ttagttacta tttattaacc ttggaccaat
    16681 ctctttcaaa agtattggca ccatctattg taagctggtt aaaagaagct tttttaaata
    16741 aatcatatgt tacagctgca taatcacatc cacaaagaga tgcttgagtt aagtggaata
    16801 catttttaat agaagctgca acaactttag tattatatcc atttattgat ataaggttac
    16861 atatttctgt aaggtttttt ataccatcat tcccattttc atcatttcta cctataaaag
    16921 ggaataggta atcagcacct gcatttatag ctaatgatgc ttgatttaca ttgaaaatca
    16981 aggtacatgc agtttttaca cctttactat ttaatatgtt tataagttct aagccaactt
    17041 cagagaaatt tatttttatt atagtgtttt tatttatatt taatatctta tcacatgaat
    17101 taattaattc gtataaatta tttccaatga cttcagcagt taatatttct ggatttaaat
    17161 tagcacatgt ctcaataaat tcatggaagt ttactttctc tttaagatac atagatggat
    17221 tagcggttat tcccttaaat ccatacttta gacacttttg aatttcatca agattagcac
    17281 tgtctatcaa atatttcata atttaattct cctttaagct atttgtcata aaaaagtgta
    17341 tatactctat ttttattatt aagtcaatta tacaataaga ttgattataa aattataaca
    17401 tgggtactta ataaaattta cataatgata tggtaataat aaaacattga ttgtctaata
    17461 attaccataa gctttagtaa ataagagtta acagtgaagg tattgcctta aaaatcctat
    17521 gatatgtata atttgaatat gaaggcaata atttaaggga ggaaaaatat gattaacttt
    17581 tatcaaccat caagaataaa ttttggacaa ggaactttaa gtgaattacc tagaataata
    17641 ggaaaatatg gaaagaaatg tttgttagtt actactccaa atgtagagcc attagacaag
    17701 ttatataaaa gagttacatt gaatttaata gaaaaaggta tagaagttgt acactttgat
    17761 taaaaaatag ctacgcacac tcgtgacttt agtcatgagt taatagctaa aatagtcagc
    17821 atatagggaa acctatatgt agagatagga tagaacctat ccaatactac ttgaattgct
    17881 ggaaacccct aaagctaacc aaactaaaac ataaggatga aataaaccta agtgtgaaag
    17941 ttacgaaagt agaaaaaatt ggttagatgg tataaggtta aatcctaagt actttaaaat
    18001 gggcaatcag caggtaagct ccgaatagga gaaacttcaa cgactattcc tcttgaggga
    18061 agtacactac aagttatcgg tagtggaagt gggtagacct taacggataa tgccgaagga
    18121 taagatatag tctgtgcttg catgaaagtg taagaagttc ataagagaac tgcataggta
    18181 gtagcgaact tatgtgaacg acaacctcaa aaatgataaa agttaagact tacggttctt
    18241 aaatatgtta tttaaaatta aatataaaac c
//
LOCUS       DAYAOO010000083        18181 bp    DNA     linear   BCT 12-OCT-2024
DEFINITION  TPA_asm: Clostridioides difficile isolate ST8-SSI-h139-18
            SAMN40601845-rid21577343.denovo.083, whole genome shotgun sequence.
ACCESSION   DAYAOO010000083 DAYAOO010000000
VERSION     DAYAOO010000083.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN40601845
            Sequence Read Archive: SRR28438827
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 18181)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 18181)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-MAY-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-MAY-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002157583.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002157583.1
            Genome Coverage       :: 163x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/11/2024 16:19:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 4,038
            CDSs (total)                      :: 3,963
            Genes (coding)                    :: 3,930
            CDSs (with protein)               :: 3,930
            Genes (RNA)                       :: 75
            rRNAs                             :: 6, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 60
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 33
            CDSs (without protein)            :: 33
            Pseudo Genes (ambiguous residues) :: 0 of 33
            Pseudo Genes (frameshifted)       :: 7 of 33
            Pseudo Genes (incomplete)         :: 25 of 33
            Pseudo Genes (internal stop)      :: 11 of 33
            Pseudo Genes (multiple problems)  :: 8 of 33
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..18181
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN40601845-rid21577343.denovo.083"
                     /isolate="ST8-SSI-h139-18"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Denmark"
                     /collection_date="2018"
                     /collected_by="Statens Serum Institute"
     gene            273..1553
                     /locus_tag="ACGI5H_003045"
     CDS             273..1553
                     /locus_tag="ACGI5H_003045"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896097.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotidyltransferase"
                     /protein_id="HFG9698741.1"
                     /translation="MNILGLIVEYNPFHNGHIYHLSKSIEKTNATHTVAIMSGNFLQR
                     GEPALFDKYTRAKIAVENGVDLVIELPTLFACQSAEIFSHGAITILNSLNCINSICFG
                     SEEGNTEILYNLAEILANEPNEFKLLLKKYLDDGLLFPTARANALFDYIHQDKKNNFI
                     QNYSKEQLSKTLNSSNNILGIEYIKNLIHLNSSIKPFTISRVQSEYNSEEIESDICSA
                     TAIRTSLKENTDLFHLKNVIPEKTYNILNEKIDNGFLPMFDDFFFDILKTIILRDMDT
                     LKEYFEVNEGIENRIYKDIFTSEFLHELQLAIKSKRYTLTKIKRTLNNILLGIKKSDV
                     QLIKNIDTIPYIRILAFNDKGREILKEIKNKSEIKIINKFSNISFSLDDTIFKTLISY
                     DIKATNIYNSIYYKNNKDLVKGPMDFYTHPIYVK"
     gene            complement(1816..3207)
                     /locus_tag="ACGI5H_003046"
     CDS             complement(1816..3207)
                     /locus_tag="ACGI5H_003046"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729521.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA];
                     GO_function: GO:0050660 - flavin adenine dinucleotide
                     binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-binding oxidoreductase"
                     /protein_id="HFG9698742.1"
                     /translation="MYKLIDKKDIDFLIDTCGEENVLVGSDINEDFSHDELGGIEKYP
                     EVLVNVLETEQVSKIMKYAYKNNIPVTPRGQGTGLVGAAVAINGGIMINLCKMNKILE
                     VDYENLTLTVEPGVLLMTIGQYVQDRDLFYPPDPGEKSATIAGNINTNAGGMRAVKYG
                     VTRDYVRGLEVVLPNGEIINVGGKVVKNSSGYSIKDLLVGSEGTLGIVTKAILKLLPL
                     PKKSISLLIPFPDLSMAIETVPKIIKSKSIPTAIEFMERDVILAAEEFLGKKFPDNTS
                     DAYLLLTFDGNSTEDIEKEYEKVANLCLENGALDVFISDTQERNDSIWSARGAFLEAI
                     KASTTQMDECDVVVPRDKIAEFIRYTHELQDKLKIRIKSFGHAGDGNLHIYILKDGMD
                     DNTWKIRLKETFDYMYKKSRELSGQVSGEHGIGYAKKEYLHESNSDAYMMLIKNIKLA
                     FDPKNILNPGKIY"
     gene            complement(3218..4438)
                     /locus_tag="ACGI5H_003047"
     CDS             complement(3218..4438)
                     /locus_tag="ACGI5H_003047"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428453.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-binding protein"
                     /protein_id="HFG9698743.1"
                     /translation="MSKIVVNQDKITDLKRILEICPFGAIEEKSGIVEISAGCKMCKL
                     CVKSGPKGAFEFIESSKVQINKDEWRGIAVYVEHHNGNIHPVTYELIGKAREMASKIK
                     QPVYCVFVGKDIKDKCSNLISYGVDEVFVYDEDEFKDFRIEPYSKAIENFIDKIKPTI
                     VLVGGTTLGRSLAPRLAARFRTGLTADCTILDIQSNTDLDQIRPAFGGNIMAHINTPN
                     NRPQFATVRYKIFSAPEKIENTTGKITLCKVEKKELKSKIKVLSVKEKNKEVGLEEAE
                     VIVVASRAIKKQEDMEMIYKLADKLNAQVAGTRPVIEAGWIDAKKQIGLSGRTVKPKL
                     IITCGVSGAVQFVAGMQGADYIVAINKDDKAPILDVAHLALIGDIYDIIPKLIEKIEN
                     NKDNNQKYMASAAK"
     gene            complement(4452..5240)
                     /locus_tag="ACGI5H_003048"
     CDS             complement(4452..5240)
                     /locus_tag="ACGI5H_003048"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428455.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="electron transfer flavoprotein subunit beta/FixA
                     family protein"
                     /protein_id="HFG9698744.1"
                     /translation="MEILTCIKQVPGTTSVEVDETTGVLKRDGVDSKMNPYDLYALET
                     ALRIKEDKKANLKVLSMGPPQAKKVIEESFMMGADEGALISDRRFGGADVLATSYTIS
                     QGIKKMGKVDLIICGKQTTDGDTAQVGPEVAEFLDIPHVTNVTKLIEVKDESIVVEID
                     MPNDLQVCEIEYPCLITVEKDIFQPRLPSFKLKLNTKDREIPVYSLDDFEDKDENNYG
                     LNGSPTQVVRIFPPKPNTDKNIVRGNADELSFALVNKLEELKLV"
     gene            complement(5257..6531)
                     /gene="larA"
                     /locus_tag="ACGI5H_003049"
     CDS             complement(5257..6531)
                     /gene="larA"
                     /locus_tag="ACGI5H_003049"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438088.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0050043 - lactate racemase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="nickel-dependent lactate racemase"
                     /protein_id="HFG9698745.1"
                     /translation="MVKLKVPYSKQGMILEIPDERFLGVLESKSDNYIEHKTQEEIVE
                     ESMNNPIGSNSLEELVKGKKNVVIITSDHTRPVPSRITMPIILRRIRNVNPEIDVKII
                     VATGFHRPSTREELIYKMGEEIVDNEDIVMHISTDDKSMCKVGILPSGGDLYINKLAY
                     EAELLIAEGFIEPHFFAGFSGGRKSVLPGIASAKTIMYNHCSDFIDSDNSRTGKLNNN
                     PIHEDMVYAAKVAKLAFILNVVIDKDKKIIASFAGDVEKAHTKGCRFVTELSKVNSIK
                     SDIVVTTNGGYPLDQNIYQSVKGMTAAEATCKDGGVIIMISACNDGHGGQSFYENVAN
                     ADSPKQLLDKIRSVDRVDTIPDQWEFQILARILSKYTVIMVTDKCNPEMIKKMHMKHA
                     FNFKEALEMANSIVGKESKVVVIPDGVSVIVK"
     gene            complement(6649..7362)
                     /locus_tag="ACGI5H_003050"
     CDS             complement(6649..7362)
                     /locus_tag="ACGI5H_003050"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896090.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="FadR/GntR family transcriptional regulator"
                     /protein_id="HFG9698746.1"
                     /translation="MFNSIASKKVYEQVIEQIQYKILNGELKKGDKLLSERELSEQMN
                     VSRTSIREAIRVLETMGVIESRQGEGNFICTNIEKTLIEPLSMIFKLNNGTLEDILEL
                     RIILEIEIAKLASKRITSSEVIELKHIIDEMRVETNKKDNNRVLVLLDQKFHSKLATL
                     SKNYLIQSLFMTASKLFDGFIEDAREKIIAEPFNENILLKQHEAIYNAVVENDVELAC
                     EKAKEHMDFISKNYRKNEN"
     gene            7487..8746
                     /locus_tag="ACGI5H_003051"
     CDS             7487..8746
                     /locus_tag="ACGI5H_003051"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896088.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sporulation integral membrane protein YlbJ"
                     /protein_id="HFG9698747.1"
                     /translation="MKKNKIIAFFAPSIIVGVLVLGIILYPNEAIKSAREGFSIWSNV
                     LVPSLLPFIIGANLIVDLKIVDIIGFIINPITRFVFNVSGKSALAFAISTVSGYPVGV
                     SLASEFRSNGQISKYEAQRLVSFCSTSGPLFIIGSVGTGMFQNSNLGYLMILCHYLGT
                     ILVGLFFRNYGNENLPKTKLDLKTNIKNVINIRNSSGNGFFVLFGNAVFNGVNTLLTV
                     GGFVIVFSVVFKILSLFNVISLIASVIYLPLSFLGVSKELCQAFVSGLFEITIGCNKV
                     SSITSSPEILRASLASFLIGFSGLSILAQCCTFLSKTDIDLKLYILSKFAHGVLAAIF
                     IFILYPIANSAVLVSSFADTYNVIYNNLIWFYYLSYYDTILQIVVIIYLISAVFIAKK
                     HMKTLSTNGKLMRYKNTFFTKKFSRKK"
     gene            9026..9592
                     /locus_tag="ACGI5H_003052"
     CDS             9026..9592
                     /locus_tag="ACGI5H_003052"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438082.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA];
                     GO_process: GO:0015074 - DNA integration [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HFG9698748.1"
                     /translation="MATRPIEIDEYKKIMELLHTGFTYSENGVEKRFRKNPKVALALM
                     LEANLGLRISDILRLKIGNFKGNMLEINEKKTGKLQYRPVNKNIIESINEHARKYNLK
                     SNDYLVNIKTKAIQKQLRIICKYLNLYNISTHSFRKLYATTQFEKSNNNLELVKELLN
                     HSSVATTQRYIRVTQQAINEASENFFIG"
     gene            complement(9793..10998)
                     /locus_tag="ACGI5H_003053"
     CDS             complement(9793..10998)
                     /locus_tag="ACGI5H_003053"
                     /EC_number="1.1.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729519.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004412 - homoserine dehydrogenase
                     activity [Evidence IEA];
                     GO_function: GO:0050661 - NADP binding [Evidence IEA];
                     GO_process: GO:0006520 - amino acid metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="homoserine dehydrogenase"
                     /protein_id="HFG9698749.1"
                     /translation="MKIAILGYGTVGSGLIDLIENNTSKRDIEVVGILVKNKEKHKYK
                     KYFDKITTDIEDIFDKDIDILVEVIGGLNPAFDYVTRALNKKIHVVTANKDLLAEKGS
                     DLIELANLNNVSIKFEASVAGGIPVLKPLIESLEGNNIKSINAILNGTCNFILSKMYD
                     ENLPYDVALKQAQELGFAEVNPDADVLGYDSARKLSILSTLSYGKIVYWKDLLLEGIT
                     SIDEKDIEYAKKLNCKIKLVARSKYESGEVSGFVRPALVDNNNMLSKIDNEFNVVILV
                     GDSVGELSFVGKGAGRGATGSAVYADIIDIIDNRSSNIKSFSKGKLDLSGLIEDECSA
                     VVRFGGYNNKDGILECLDKYVDSYDIIDDEELAIFVSAKSEHEIDRVLEIVKRNNYSE
                     SAKKLLKID"
     regulatory      complement(11101..11207)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00162"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="SAM riboswitch class I; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="S-adenosylmethionine"
                     /db_xref="RFAM:RF00162"
     gene            complement(11299..11667)
                     /locus_tag="ACGI5H_003054"
     CDS             complement(11299..11667)
                     /locus_tag="ACGI5H_003054"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428464.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YhbY family RNA-binding protein"
                     /protein_id="HFG9698750.1"
                     /translation="MLKGKQRAYLRSLANTLKPTTQIGKEGVTESFLEQLDGMLRTRE
                     LVKVTILENAGLDTKETANAVCEALRAEFVQAIGFKFTIYKRNIEEPKILFPGHEQAK
                     AKTKNNNVTKKGKPTKRAVR"
     gene            complement(11719..12996)
                     /gene="obgE"
                     /locus_tag="ACGI5H_003055"
     CDS             complement(11719..12996)
                     /gene="obgE"
                     /locus_tag="ACGI5H_003055"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888921.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003924 - GTPase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GTPase ObgE"
                     /protein_id="HFG9698751.1"
                     /translation="MFIDKARIFVKAGNGGNGSVAFRREKYVPAGGPDGGDGGRGASI
                     IFEVDLGLRTLMDFKYQKKYQAQNGGDGSKGKRAGKNGENLVLKVPAGTVIRDEATGL
                     VLADLKKEGDTAIVAKGGIGGKGNQHFANAVRQAPAFAKSGTDGEERWITLELKMIAD
                     VGLLGFPNVGKSTFLSVVTKAKPKIANYHFTTLTPNLGVVQTKFGDSFVLADIPGIIE
                     GASEGIGLGHEFLRHVERTKVLIHIVDISGLEGRDPIEDFDKINDELKLYNEKLSKRP
                     QVVVANKFDILEDESKFEKFKSELEGRGYTVFKMSAATRQGIDEVIAYVSKMLKEVED
                     VELVSEEEMYRPELDIGTEEELSIDIEDGVYVVTGKALRRIMYSVNFDDMESLQYFQK
                     AMESQGVFDRLREMGIEDGDVVKIYELEFEFYN"
     gene            complement(13107..13397)
                     /gene="rpmA"
                     /locus_tag="ACGI5H_003056"
     CDS             complement(13107..13397)
                     /gene="rpmA"
                     /locus_tag="ACGI5H_003056"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419086.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0000315 - organellar large ribosomal
                     subunit [Evidence IEA];
                     GO_component: GO:0022625 - cytosolic large ribosomal
                     subunit [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L27"
                     /protein_id="HFG9698752.1"
                     /translation="MLNMNLQLLASKKGVGSSKNGRDSISKRLGVKRFDGQLVTAGSI
                     IVRQRGTKIHPGTNVGKGSDDTLFALVDGTVKFERKDKKRKKVSIYPVAIAE"
     gene            complement(13411..13728)
                     /locus_tag="ACGI5H_003057"
     CDS             complement(13411..13728)
                     /locus_tag="ACGI5H_003057"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438074.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosomal-processing cysteine protease Prp"
                     /protein_id="HFG9698753.1"
                     /translation="MIKVKYYYNDDFLLQGFCLKGHADFAEIGYDIVCAAVTSNAIAV
                     INSLDKLQKIEFEKVVGEEGHIECIVKDTHVKDAQLLLNHFQLAVKEIKREYPKNIKI
                     LKK"
     gene            complement(13743..14054)
                     /gene="rplU"
                     /locus_tag="ACGI5H_003058"
     CDS             complement(13743..14054)
                     /gene="rplU"
                     /locus_tag="ACGI5H_003058"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000270907.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L21"
                     /protein_id="HFG9698754.1"
                     /translation="MYAIVKTGGKQYKVSEGDVLFVEKLEANAGDVVTLNEVLACSKD
                     GELKLGSPVVEGASVQAKVVEQGKAKKVIVFKYKAKKDYRRKQGHRQSYTKIVVEKIN
                     A"
     gene            complement(14155..15576)
                     /locus_tag="ACGI5H_003059"
     CDS             complement(14155..15576)
                     /locus_tag="ACGI5H_003059"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0004540 - RNA nuclease activity [Evidence
                     IEA];
                     GO_process: GO:0006396 - RNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Rne/Rng family ribonuclease"
                     /protein_id="HFG9698755.1"
                     /translation="MKKIVIESLIGSQKTAVLEDERLTELFVEDNLNKKTVSNIYRGI
                     VKKVIPGIEACFVDIGFKKLAYLQLKKGSTIKSGQDILVQINKEEIGTKGAKLNTEIS
                     ISGRYIVYIPSNDRTTISNKITDEKERFRLKKITKAVNKENLGLIIRTEAQGCTHDEI
                     KKDIEELKLKYENILKEYKLGIGPKLLYKSLDFATKYVKDNVNDDIESIITNSYDKYS
                     ELKSILRGIDKTYVDKLCLEENRDVFDLYRIESKIEKLLNKKVWLKSGGYLIIEKTEA
                     LTVIDVNTGKFIGTGKLDETVYKTNLEAAKEIVRQLRIRDIAGIIIIDFIDMHKKKHQ
                     KEILHILEEEFNKDKRKAEVLGMTKLGLVEVARRREKESIDKYYLMSCPCCDGEQTIK
                     SVHYILDSIEKEIMRISEHTVYKNIMVEFNDFIFEQIKEYYMDIIDKIGEKYNIKISL
                     NANSTLKHNKTNVIFDKIVDNKM"
     gene            complement(15594..16295)
                     /locus_tag="ACGI5H_003060"
     CDS             complement(15594..16295)
                     /locus_tag="ACGI5H_003060"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438070.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR03936 family radical SAM-associated protein"
                     /protein_id="HFG9698756.1"
                     /translation="MSKIIRVKFKKEGDMIYISHLDLQRLLQRAFRRAEINLSHSQGF
                     NPHPKMSYGNALALGAESQGEYVDIEIEEDDLSVEEFLNKVSIQLPDGIDFIKAKEID
                     RQTPSLSSVIDYGEYLFNIDLKRPMTKEFVKRKVIDFMNNKEIIITKKNKKGKMVEVD
                     IRPMIRTFDVLNLEDEHITLTATIATGSKTNLNTNILIPKILEMFELDIDPLDVDILR
                     RDLYVLEDGELVTPM"
     gene            complement(16297..18141)
                     /locus_tag="ACGI5H_003061"
     CDS             complement(16297..18141)
                     /locus_tag="ACGI5H_003061"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428473.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0051539 - 4 iron, 4 sulfur cluster binding
                     [Evidence IEA];
                     GO_function: GO:1904047 - S-adenosyl-L-methionine binding
                     [Evidence IEA];
                     GO_process: GO:0008152 - metabolic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR03960 family B12-binding radical SAM
                     protein"
                     /protein_id="HFG9698757.1"
                     /translation="MNKVDLKKILKKVEKPARYLGNEINSIHKDTSNSELIRYAHCFP
                     DLYEVGMSHLGSHILYDVINKDEDVFCERVYSPAVDMENIMREKSIPLFALESREPIT
                     NFDFVTFTLQYELSYTNILNILDLANIPILKEERTLEDPFIMVGGPCAYNSEPLADFV
                     DVVILGEGEEVNLEVVNEYKEWKKNKTTREDFLYKISSIEGVYIPSFYDVKYNEDGTV
                     QSVTPNREGITKNPTKRIIKDVETVDYPEKLIVPYIDTVHDRIVLELFRGCTRGCRFC
                     QAGMIYRPIREKSVKRLKEILDKLVKNTGYDEISLSSLSTSDYSKLSELTDYLVDEYA
                     SNNIGISLPSLRLDNFSMEIADKIQQVRKSGLTFAPEAGTQRLRDVINKGVTEEDLEN
                     ATERAFEMGWNSVKLYFMIGLPTETYEDLDGIAKLAYKVIDIYRKVNGGKLKRSFSVT
                     VSTSTFVPKPFTPFQWHGQDTTEEVINKQRHLVNKLRNNNIKYNYHDSKTSLMEAVVA
                     RGDRRIGKVIYDAFRLGAKFDGWAEHFNLDIWKEAMEKNNLSIDFYAHRNRNYEEVFP
                     WDHIDVGISKKFLIREDENAKKEKITSDCRHNCNGCGINIHDIGRGLC"
BASE COUNT         5788 a         3305 c         1939 g         7149 t
ORIGIN      
        1 tttctagtat ggtaaattgt gtatttcact aataatatat taacaagtta acttaatgta
       61 gattattctt tcccatttgt tataataata taatataaag agctaataaa gttattttaa
      121 taacatttaa ccagtttttt atgtaggtaa catttctaca tttttataaa tttttttacg
      181 ttttttaatt ttataattaa aaatttaaat tttatacata ttataataaa ttgtgatata
      241 tataaaataa ttaaagataa aaggagtatt ttatgaacat acttggatta atagttgaat
      301 ataacccatt tcataatgga cacatatatc atttatctaa atctatagaa aaaacaaatg
      361 caacacatac tgtagcaata atgagtggaa attttctaca aagaggcgaa ccagctttat
      421 ttgataaata cactagagca aaaattgctg tcgaaaatgg tgtagactta gttatagaat
      481 taccaacttt atttgcttgt caaagtgctg aaattttttc tcatggtgct ataacaattt
      541 taaattcact aaactgcata aattctatat gttttggtag tgaagaagga aatacagaaa
      601 ttctttataa tctagctgaa attttagcaa atgaaccaaa tgaatttaag ttacttttaa
      661 aaaaatattt agatgatggt ctgttatttc caacagctag agctaatgca ctttttgatt
      721 atatacatca agacaaaaaa aataatttta tacaaaatta ttcaaaggaa caattatcaa
      781 aaacattaaa ttcatcaaac aacatactgg gtatagaata cataaaaaac ctcatccatt
      841 taaacagtag tataaaacca tttactatct ccagggtcca atcagaatat aattccgaag
      901 aaattgagag tgatatttgt tctgctactg ctataagaac ttcacttaaa gaaaatacag
      961 acctttttca tttaaaaaat gttattccag aaaaaactta taacatccta aatgaaaaaa
     1021 tagataatgg ttttttacct atgtttgatg acttcttctt tgatatttta aaaacaatta
     1081 tacttagaga tatggacact ttaaaagagt attttgaagt aaatgaaggc atagaaaaca
     1141 gaatctataa agatatcttt acatctgaat ttctacatga actacaatta gcaattaaat
     1201 ccaagcgata cactttaacc aaaatcaaac gaactctaaa caatatattg ttaggtatta
     1261 aaaaaagcga cgtgcaactt ataaaaaaca tagatactat accttatata agaatacttg
     1321 cttttaatga taaaggtaga gaaattctaa aagagataaa aaataaatct gaaataaaaa
     1381 taataaacaa gttttcaaat atatcatttt cattagatga tacgattttt aaaacactca
     1441 taagttatga tataaaagct acaaatatat ataattcaat atattataaa aacaataaag
     1501 atttagtaaa aggccctatg gatttttata ctcatccaat atatgtaaag tagtttttta
     1561 aaataactat atttataaaa atcattttat taactcttta ttatataaga tacaatagtc
     1621 ttactttatt tatgtacaca tgcttttagg atgacaacat caacttaaat attatgttac
     1681 tttctaaatt taagtaaata ttgccatcct aaaaatttta caatttagct tcagatttaa
     1741 aagtaaagtt taaaatatta tatttaaatc taatttaata ttttttgttt tataaatatt
     1801 attaaattaa tatttctaat atattttccc tggatttaaa atatttttag ggtcaaaagc
     1861 taactttata tttttaatta acatcatata agcatctgaa tttgattcat gtaagtactc
     1921 ttttttagca tatcctatgc catgttcacc agaaacttga ccactaagtt ctctagattt
     1981 tttatacata tagtcaaaag tttcttttaa tcttattttc catgtattat catccatacc
     2041 atcttttaaa atatatatgt gtagatttcc atctcctgca tgaccaaaac tttttattct
     2101 tatttttaat ttgtcttgaa gctcgtgagt gtatcttata aactctgcta tcttatctct
     2161 tggaacaacg acatcacatt catccatttg tgtcgtagat gcctttatag cttctaaaaa
     2221 tgcacctctg gctgaccata tagaatcgtt tctttcttgt gtatctgata taaatacatc
     2281 taatgcacca ttttctaaac ataaattagc tactttttca tattcttttt ctatatcttc
     2341 agtgctattt ccatcaaatg taagcaaaag ataagcatct gatgtattat ctggaaactt
     2401 tttacctaaa aattcttctg ctgccaatat cacatctctt tccataaatt ctatagccgt
     2461 tggtattgat tttgatttta ttattttagg aacagtttct attgccattg ataaatctgg
     2521 aaatggtata agcaaactta tacttttctt tggtaaagga agcaatttta atatagcttt
     2581 agtaactatt cctaaagtac cttctgagcc cactaataaa tcctttatac tatatccaga
     2641 actattttta accacctttc cacctacatt tataatttct ccatttggta gtacaacttc
     2701 aagtcctctt acataatccc ttgtaacgcc atattttact gctctcatac cacctgcatt
     2761 agtgtttata ttacctgcaa ttgtagcact tttttcacct gggtcaggtg ggtaaaataa
     2821 atctctatct tgaacatatt gacctattgt catcaataaa acacctggtt ctactgtcaa
     2881 tgttaaattt tcataatcaa cttcaagtat tttattcatt ttacatagat taatcattat
     2941 tccaccattt atggcaacag cagcacctac aagaccagta ccttgacctc ttggtgtgac
     3001 tggtatatta tttttatatg cgtatttcat tattttagat acttgttcag tttcaagtac
     3061 atttactaaa acttcagggt acttctcaat ccctccaagt tcatcatgtg aaaaatcttc
     3121 atttatatca cttccaacta atacattttc ttctccacaa gtatctatta aaaaatctat
     3181 atctttttta tcgattaatt tatacatttc tatcccccta tttagctgct gatgccatat
     3241 atttttgatt attatctttg ttattttcta ttttttcaat caatttagga ataatatcat
     3301 aaatatcacc tattaaagct aaatgtgcta catcaagtat aggcgcttta tcatctttat
     3361 ttattgctac tatatagtca gcaccctgca tccctgcaac aaattgaact gctccagata
     3421 caccacaagt tattatcaat ttaggtttta cagttctacc actaagacct atttgttttt
     3481 tagcatctat ccaacctgct tctattacag gtcttgttcc tgccacttga gcgtttaact
     3541 tatcagctaa tttatatatc atctccatat cttcttgttt ttttattgct ctacttgcca
     3601 caactatcac ttcagcttct tccagaccaa cttctttatt tttttctttt acactcagta
     3661 ccttaatttt agattttagt tctttttttt ctactttaca taaagttatc tttcctgtag
     3721 tattctctat tttttctggt gctgaaaata ttttatatct tacagtggca aattgtggtc
     3781 tattattagg tgtgtttata tgagccatta tatttccacc aaatgctggt cttatttggt
     3841 ctaaatcagt atttgattga atatcaagta ttgtacaatc tgctgtaaga cctgttctaa
     3901 atctagcggc aagtcttgga gctaatgacc tacctaatgt agttccacca actaatacta
     3961 tcgttggttt tattttatct ataaagtttt ctattgcttt tgaatatggt tctatcctaa
     4021 aatctttaaa ttcatcttca tcatatacaa atacttcatc caccccataa gaaatcaaat
     4081 tactgcactt atcttttatg tcttttccta caaatacaca atacacaggt tgttttattt
     4141 ttgatgccat ctcacgagct ttacctataa gctcgtacgt tacaggatgt atatttccat
     4201 tatgatgttc aacatatact gcaattcccc tccattcatc tttattaatt tgtactttac
     4261 tactctctat aaattcaaat gcgccttttg gtccactttt gacacacaac ttgcacatct
     4321 tacagccagc acttatttct actatacctg acttttcttc tatagcccca aaaggacata
     4381 tttctaaaat tctctttaag tcagttattt tatcttgatt tacaactatc tttgacattt
     4441 attactcccc cttacaccaa ctttaattcc tctaatttat ttacaagtgc aaaacttagt
     4501 tcatctgcat ttcctcttac aatattttta tctgtatttg gctttggagg aaatattctt
     4561 acaacttgag taggagaacc attaagtcca tagttatttt catctttatc ttcaaagtca
     4621 tctaagctat atacaggtat ttctctatct ttagtattaa gttttaattt aaatgaaggt
     4681 agtcttggtt gaaaaatgtc tttttctaca gttattaaac atggatattc aatctcacat
     4741 acttgtaaat catttggcat atctatttca acaactatac tttcatcttt aacttcaatt
     4801 aattttgtaa cgttagtaac atgaggtata tctaaaaatt cagctacttc aggtcccacc
     4861 tgtgctgtat caccatcagt agtttgtttt ccacaaatta ttaggtctac ctttcccatc
     4921 ttcttaatac cttgtgatat ggtataggaa gtagccaata catctgctcc tccaaatctc
     4981 ctatcactta ttaatgctcc ttcatcagct cccatcataa aactttcttc aattaccttc
     5041 tttgcctgag gaggacccat gctaagtact tttagattcg ctttcttatc ttcctttatt
     5101 ctaagagctg tttctaaagc atataggtca tagggattca tttttgaatc tactccatct
     5161 ctttttagta ctcctgtagt ttcatcaact tctactgaag tcgttccagg aacttgttta
     5221 atacatgtca aaatttccat aaagtacact ccttttttat ttaactataa ctgatactcc
     5281 atcaggtata actactactt tgctctcctt accaactata ctattcgcca tttctaaagc
     5341 ttctttaaag ttaaatgcat gtttcatatg catttttttt atcatttcag gattacactt
     5401 atctgttacc attatcacag tatatttaga taatattctc gctagtatct gaaattccca
     5461 ttggtctgga atcgtatcta ctctatcgac acttctaatt ttatctaaaa gttgttttgg
     5521 agaatctgca tttgctacat tttcataaaa agattgacct ccatgaccat cattacatgc
     5581 tgaaatcatt attattactc caccgtcttt acaagtagct tcagctgctg tcattccttt
     5641 aacagattga taaatatttt ggtctagtgg atatccacca tttgtagtta caacaatatc
     5701 agattttata gaatttactt ttgataactc tgttacaaat ctacatcctt tagtatgtgc
     5761 tttttcgaca tcaccagcaa aggaagcaat tattttttta tctttatcta ttacaacatt
     5821 caatatgaat gctaattttg caactttagc tgcatatacc atatcctcat gaataggatt
     5881 attattcaat tttccagttc ttgaattatc actatctata aagtcactac aatgattgta
     5941 cattatagtc tttgcagatg cgattcctgg aagtacactt tttctgccac ctgaaaaacc
     6001 tgcaaagaaa tgaggttcta taaaaccttc tgctatcaaa agttctgcct catatgctag
     6061 tttgtttata tataaatctc cacctgaagg caatatccct actttacaca tagatttatc
     6121 atcagtagat atatgcataa ctatatcttc attatctact atttcttctc ccattttata
     6181 aattagctct tcccttgtac ttggcctatg aaatccagtt gccactataa tcttcacatc
     6241 aatttctgga ttaacattcc taatccttct taatataatt ggcatagtta ttctacttgg
     6301 tacaggtctt gtatggtcac ttgtaattat gactacattc tttttcccct taaccagttc
     6361 ttccagagaa ttagagccta taggattatt catagattct tcaactatct cttcttgagt
     6421 cttatgttct atataattat ccgattttga ctccaaaaca ccgagaaaac gttcatcagg
     6481 tatttctaaa atcattcctt gttttgaata cggtactttt aactttacca tttttaatct
     6541 cccattataa taaactataa aattggtatg tggtcatacc agttttacat ttatatgata
     6601 gtaccattat ctaccatttg caagaataat ttattttata acaaactttt aattttcatt
     6661 ttttctataa tttttactta taaaatccat atgttccttt gctttctcac atgcaagttc
     6721 tacatcattt tctacaactg cattgtatat agcttcatgc tgtttaagca atatattttc
     6781 attaaaaggt tctgcgatta ttttttctct tgcatcttct ataaatccat caaataattt
     6841 tgatgctgtc ataaaaagac tttgaattaa ataattttta cttaatgttg ctagtttact
     6901 gtgaaatttt tggtctaata acaccagtac tcgattatta tcttttttat tagtttctac
     6961 cctcatttca tctattatat gtttcaattc tataacttca gaagaagtta ttctctttga
     7021 agcaagtttt gcaatctcaa tttctaggat tattctaagc tctaatatat cttcaagtgt
     7081 accattatta agtttaaaaa tcatagataa aggttctatt aaagtttttt ctatatttgt
     7141 acatataaaa tttccttcac cctgtctgct ttctatcact cccatagtct ctaataccct
     7201 aatagcttcc cttatggaag ttctactcac attcatttgt tcagacagtt ctctttctga
     7261 tagtaattta tccccctttt ttaactctcc atttagtatt ttatattgta tttgctcaat
     7321 tacttgttca taaacttttt tactagctat actattaaac attttttcct ccaatatgat
     7381 aatcgttgtt gtaatatata tctattatat atcttaagcc attacattca tatattttta
     7441 ttacttttaa tataatatct tataactcaa atttacaggt gatattatga aaaaaaataa
     7501 aattattgct ttttttgctc catctatcat agttggagtt ctagttttag ggattatcct
     7561 atacccaaat gaagctataa aatctgcaag agaaggcttt tctatatggt ctaatgtttt
     7621 agttccatca ctactaccat ttataattgg agcaaactta attgttgatt taaaaatagt
     7681 ggatattata gggtttatca tcaatcccat aactagattt gtatttaatg tttcaggaaa
     7741 gagcgcttta gcttttgcta tatctacagt atctggttat ccagtaggag taagtttagc
     7801 ttctgaattt aggagtaatg gacaaatttc taagtatgaa gcacaaagac ttgtgtcttt
     7861 ttgttctaca tcaggacctt tattcataat aggttcggtt ggtacaggta tgttccaaaa
     7921 ttcaaactta ggttatttaa tgattctctg ccattatcta ggaactatat tggttggtct
     7981 tttctttaga aattatggta atgaaaatct tccaaagaca aaattggatt taaaaacaaa
     8041 tataaaaaat gtaatcaaca ttagaaattc aagtgggaat ggtttttttg ttttatttgg
     8101 aaatgctgta tttaatggag taaatacatt acttacagtt ggtggatttg taattgtttt
     8161 ttcagtagta tttaaaatac tatctctttt taatgtaatc tcattaatag catcagttat
     8221 atatttgcct ctttcatttt taggtgttag taaagaactc tgtcaagcat ttgtaagtgg
     8281 tctatttgaa attactatag gatgcaataa agtatctagt ataacaagtt ctccagaaat
     8341 tttaagagca tctttagcta gttttttgat aggatttagt ggattatcca tcctagctca
     8401 atgttgtaca tttctatcaa aaacggacat agatttaaaa ttatacatac taagtaaatt
     8461 tgcgcatgga gttttagctg ctatctttat atttatactt tatccaattg caaactctgc
     8521 tgtgttggtt tctagctttg ctgatacata caacgttata tataataatt taatctggtt
     8581 ttattatctt agctattatg atacaattct tcaaattgta gtaataattt atctaatctc
     8641 agccgtattt attgcaaaaa aacatatgaa aactttatct acaaatggga aactaatgcg
     8701 atataaaaat acttttttca ctaagaaatt ttcacgaaaa aaataaaact aaaaataaaa
     8761 ctaataaaac ttaactaaat acttccattt ttttattata tttgtcataa ttttaataac
     8821 ctttttaatt agtttaacag catagttatt tcatcacaat ttaataattt tattagaaat
     8881 atttttcaaa aaattctcct taatcacata tatcacactt gtataagttt actgggaaat
     8941 ttttccatta tataatattt catttatatt atataataaa taccgaccta aacttaccaa
     9001 atcaaactaa gaggagtggt tgaaaatggc aacaagacct atagaaatag acgaatataa
     9061 aaagataatg gaactattac atactggctt tacttatagt gaaaatggcg ttgaaaaaag
     9121 atttagaaaa aatcctaaag ttgcattggc actaatgtta gaagctaatt taggtctaag
     9181 aatatcagat attttaagat taaagatagg taattttaaa ggtaatatgt tggaaataaa
     9241 tgaaaaaaag acgggcaaat tacagtatag accagttaat aaaaatataa ttgagtccat
     9301 aaatgaacat gcaagaaagt ataatcttaa atcaaatgac tacttagtaa atataaagac
     9361 aaaggctatt caaaaacagt tgaggataat ttgtaaatac ttaaatctgt ataatataag
     9421 tacacatagc tttagaaagc tctatgctac tactcaattt gaaaagagta acaataattt
     9481 agagttggtt aaagaacttt taaatcacag ctctgtagcc actacacagc gatatataag
     9541 ggtaactcag caagctatta atgaagctag tgaaaatttc tttattggtt aattataacg
     9601 tatacatttt tctattatct tattaattca ccagatatta aaaaagagtg tctcaaaatg
     9661 aactttttag ttcatgagac actctttttt tataaaatca aatatatttt tattatttca
     9721 acactggaaa aaaggcttat ctctctattt tgagacaccc tattaaattt tcataattct
     9781 tgcataaaca tattaatcta tcttcaataa ttttttagct gattcactgt aattatttct
     9841 ttttacaatt tccaaaactc tatcaatctc atgttctgac tttgcactta caaaaatcgc
     9901 caattcttca tcatctataa tatcataact atctacatat ttatctaaac attctaaaat
     9961 tccatcttta ttattatacc caccaaatct aactactgca ctacactcat cttctataag
    10021 tccacttaaa tccaatttcc cttttgaaaa agactttata tttgaacttc tattatctat
    10081 tatatctata atatctgcat aaacagcact tcctgttgca cctcttccag ctcccttacc
    10141 tacaaaagaa agttcaccta ctgaatcacc tactaaaata actacgttga actcattatc
    10201 tatctttgaa agcatattat tattgtccac taatgctggt ctaacaaatc cacttacttc
    10261 tcctgattca tacttacttc tagcaaccaa ttttatctta caatttaatt tttttgcata
    10321 ttctatatct ttttcatcta ttgaagttat tccttctaat aataaatctt tccaatatac
    10381 tatttttcca taagataaag tagacaatat agataacttt ctagcactat catatcctaa
    10441 aacatctgca tctggattaa cttctgcaaa tcccaactct tgtgcctgtt ttaaagcgac
    10501 atcatacggt aaattttcat catacatctt tgataatata aaattacaag tcccatttaa
    10561 aatagcgttt atgctcttta tattgttgcc ttccagtgat tctatcaatg gttttaaaac
    10621 tggaatacca cctgccacag atgcttcaaa cttgatgcta acattattta agttagctaa
    10681 ttctataagg tcactacctt tttcagccag taaatcttta ttagctgtca ctacatgtat
    10741 ttttttattt aacgctcttg ttacataatc aaaagctgga tttaatcctc caattacttc
    10801 aactagtata tcaatatcct tgtcaaatat atcttctata tcagtagtta tcttatcaaa
    10861 atacttctta tacttgtgtt tttctttatt tttaactaaa attccaacaa cttctatatc
    10921 tctttttgaa gtattatttt ctattaaatc aattaatcca cttcctactg ttccataccc
    10981 taatattgct atcttcactg taacataccc ccatcatttt gattatatta aattatttat
    11041 atatataaat ataccaataa aaaaagcttg agtataaact caagccatat gacgggttta
    11101 tactcatctt tcagcataaa tgctgcagga tttagcacca atgtataatt aaatatactg
    11161 gttgccgggc ttcacagggc cagtccctct gccactcttg ataagattgc taatttaaat
    11221 ttatgtttaa tagtataata caatttcttc caattgtcac tattttttta acttatttcc
    11281 ctaaaaggat ataaactatt atctaacagc tcttttagtt ggtttaccct tttttgtaac
    11341 attattattt ttagtctttg ctttcgcctg ttcatgtcct ggaaaaagta ttttaggctc
    11401 ttcaatattc ctcttgtaaa tagtaaattt aaaaccaata gcctgcacaa attcagctct
    11461 taaagcttca catactgcat tagcagtttc tttagtatca agacctgcat tttctaatat
    11521 agtaactttt actaattctc tagttcttaa cataccatct aattgctcta agaaactctc
    11581 tgtaacacct tctttaccaa tttgtgtagt aggctttaaa gtatttgcca aagatcttaa
    11641 atacgccctt tgttttcctt ttaacatatt ctcacctcta taattctata cttaaattat
    11701 ctataatcta tatttaaatt aattgtaaaa ctcaaattct aattcataaa ttttaaccac
    11761 atctccatct tctattccca tttctctaag cctatcaaaa acaccttgac tctccatagc
    11821 tttttggaaa tattgaaggg attccatatc atcaaaattt acagaataca ttattcttct
    11881 aagtgcttta cctgtaacta catacacacc atcttcaata tctatactta actcttcttc
    11941 agtaccaata tcaagttctg gtctatacat ttcttcttct gaaactagct ccacatcttc
    12001 tacttctttt agcattttag aaacataggc tattacttca tctatgcctt gacgagttgc
    12061 tgctgacatt ttaaatactg tatatcctct gccttctaat tcactcttaa acttctcaaa
    12121 cttactctca tcttctaata tatcaaattt atttgcaact acaacttgtg gtctctttga
    12181 aagcttttca ttgtacaatt taagctcatc atttatcttg tcaaaatctt caatagggtc
    12241 tcttccctct aatccagata tatctacaat atgtatcaat acctttgttc tctcaacatg
    12301 tcttaagaac tcatgaccta atcctatgcc ttcagaagca ccctctataa ttccaggtat
    12361 atctgcaagt acaaaactat ctccaaactt agtttgaaca acacctagat ttggtgtaag
    12421 tgttgtaaaa tgatagtttg caattttggg tttagcttta gttacaactg atagaaatgt
    12481 tgatttacct acatttggaa atcctaaaag accaacatct gctatcattt taagttcaag
    12541 agttatccat ctttcttctc catctgtacc agattttgca aaagctggag cttgtcttac
    12601 tgcatttgca aagtgttggt tacctttacc acctatacca ccttttgcaa ctatagctgt
    12661 atctccttct ttttttaaat ctgctaatac aagacctgta gcctcatctc ttattactgt
    12721 acctgctggt acttttaata ctaaattttc tccattttta ccagctcttt ttcctttgct
    12781 tccgtcgcca ccattttgag cttgatattt tttctggtac ttaaagtcca ttagagttct
    12841 aagccccaaa tcaacttcaa atatgatgct tgctccacga ccaccatctc caccgtctgg
    12901 accaccagct ggaacgtatt tttctcttct aaatgctacc gaaccatttc caccatttcc
    12961 agccttaaca aatattcttg ccttatctat aaacaaattc ttcacctact taattaaaaa
    13021 cttttaatta gcattaccaa aaataccatt ataaattcat cagtattata agaaaaagga
    13081 gtgcctcaac actcctttta tgtatattac tcagctattg ctactggata tatactaact
    13141 ttttttctct tcttgtcttt tctttcgaat ttaacagtac catcaactaa tgcaaataaa
    13201 gtatcatcac taccttttcc aacattagtt cctggatgta ttttagttcc tctttgtcta
    13261 actattatac ttccagcagt tactaattga ccatcgaatc tcttaacacc taatctttta
    13321 gatatagaat ctctaccatt tttagaagaa cctacccctt ttttagatgc taataattgt
    13381 aaattcatgt ttaacatatg gagtcacccc ctactttttt aaaattttta tattttttgg
    13441 gtattcccgt ttaatttctt taaccgctaa ttgaaagtga tttagtaata attgtgcgtc
    13501 ttttacatgt gtatctttga ctatacactc tatatgacct tcttctccta ctactttttc
    13561 aaattcaatc ttctgtaatt tgtctaaaga atttataact gcaatagcat tagatgtaac
    13621 tgcagcacat actatatcat agcctatttc agcaaaatca gcatgtccct ttaaacaaaa
    13681 accttgcaac aagaaatcat cattataata atatttaact tttatcataa cttaaccaat
    13741 aactaagcgt ttattttttc tacaactatc ttagtgtatg attgacgatg tccttgtttt
    13801 cttctgtaat ctttttttgc tttatacttg aaaactataa ctttcttagc tttaccttgt
    13861 tcaacaactt tagcttgaac agatgctcct tctactactg gagaacctaa ttttaattct
    13921 ccatctttag agcaagctaa tacttcgttt aaagtaacaa catcacctgc gttagcttct
    13981 aatttttcaa cgaataatac atcaccttca gaaactttat attgctttcc accagtcttt
    14041 actatagcgt acattaaata cacctcctcg gcctcaaact cgccagtaca aggtacttca
    14101 tttgaagatt taaaccttta ctgtgcggca ttacaattat taattataaa atatttacat
    14161 tttattgtca actattttat cgaaaataac attggtttta ttgtgcttta atgtactatt
    14221 tgcgtttaaa gaaatcttta tattatattt ttcaccaatt ttatcaatta tatccatata
    14281 atattctttt atttgttcaa aaataaaatc attaaattct accattatgt ttttgtaaac
    14341 agtatgttca cttattctca taatttcttt ttcaatacta tctagtatat aatgtacaga
    14401 ttttattgtt tgttcaccat cacaacatgg acaagacatt aaataatact tatcaatgga
    14461 ttctttttct ctacgcctag caacttctac taaaccaagt tttgtcatac ctaatacttc
    14521 agcttttctt ttatctttat taaattcttc ttctaggatg tgtaaaatct ccttttgatg
    14581 cttcttttta tgcatatcaa taaaatcgat tattattatc ccagctatgt ctctaattct
    14641 aagctgtctt acaatttctt ttgcagcttc aagattagtt ttataaacgg tttcatcaag
    14701 tttaccagtt ccaataaact tacccgtatt tacatctata accgtaagag cttctgtttt
    14761 ttcaattatt aaataacctc cactctttaa ccatactttt ttatttaata atttttctat
    14821 tttagattct attctgtata aatcaaatac atctctattt tcctcaagac acagtttatc
    14881 aacataagtc ttatctatac ctcttaaaat agacttaagt tcagagtact tatcataact
    14941 attggtaatt atagattcaa tatcatcatt cacattatct tttacatatt tagttgcaaa
    15001 atctaaagac ttatataata atttcggacc tataccaagt ttatattctt ttaaaatgtt
    15061 ttcatacttt aatttcaact cttctatatc tttctttatt tcatcatgag tgcaaccttg
    15121 agcctcagtc cttattatta atcctagatt ttccttattt actgccttag taattttttt
    15181 taatctaaat cgttcttttt catcagtaat tttatttgat attgtagttc tatcattgga
    15241 aggtatatag acaatatacc ttccagaaat actaatctca gtgtttaatt ttgcgccttt
    15301 agttcctatt tcttctttat ttatctgaac caaaatatcc tgaccagatt ttatagtact
    15361 tccctttttt aattgtaaat aagcaagttt cttaaatcca atatctacaa aacaagcttc
    15421 tattcctggt ataacttttt ttacgattcc acgatatata ttggatacag tcttcttatt
    15481 taaattgtct tcaacaaaaa gttctgttaa tctttcatct tcaagtactg ctgttttctg
    15541 ggaccctatt agggactcaa taactatctt tttcacaact tcacctctcg agcttacata
    15601 ggagtcacta attccccatc ttctaataca tataaatctc ttctcaatat atcaacatct
    15661 aatgggtcaa tatcaagttc aaacatctct aatatctttg gtataagtat attagtattt
    15721 aaattagttt ttgagcctgt agctatagta gcagtaagag taatatgttc atcttctaaa
    15781 tttaaaacat caaaggttct tatcataggt cttatatcta cttcaaccat cttacctttt
    15841 ttattctttt ttgttatgat tatttcttta ttattcataa agtcaattac ttttcttttt
    15901 acaaactctt tcgtcatagg tcttttcaaa tctatattaa acaaatattc tccatagtct
    15961 atcacagaag aaagagaagg tgtttgtcta tcaatttctt ttgctttgat aaaatctatc
    16021 ccatctggaa gttgaattga tactttattt aaaaattcct ctactgataa atcatcttct
    16081 tctatttcaa tatctacata ctcaccttga ctttctgccc ctaaagccaa agcattgcca
    16141 taactcattt tagggtgagg attaaatcct tgagaatgtg ataagtttat ttcagctctt
    16201 ctaaacgctc tttgtaacaa tctctgaagg tcaagatgtg atatatatat catgtcgcct
    16261 tcctttttaa attttactct tattatctta ctcatattag caaagccccc ttcctatatc
    16321 atgtatattt attccacaac cattgcagtt atgtctacaa tcagaagtga ttttttcttt
    16381 tttagcattt tcgtcttctc taattaagaa ttttttacta atacctacat ctatatggtc
    16441 ccaaggaaat acctcttcat agtttctatt tctatgtgca taaaaatcta tagaaagatt
    16501 attcttttcc atagcttctt tccatatatc taaattaaaa tgttctgccc atccatcaaa
    16561 tttagcacct agtctaaatg catcatatat aacttttcct attcttctat cgcctctagc
    16621 tactactgct tccatcaaac tagtctttga atcatgataa ttgtatttta tattgttatt
    16681 tcttaattta tttactaaat gtctctgctt attaataact tcttctgtag tatcttgacc
    16741 atgccattgg aaaggtgtaa atggctttgg tacaaatgta gaagtactca ctgtaacact
    16801 aaaacttctc tttagctttc ctccatttac ttttctataa atatcaataa ctttataagc
    16861 caatttagct ataccatcta aatcttcata agtctcagtt ggtaaaccaa tcataaaata
    16921 caacttaaca ctattccacc ccatctcaaa agctctttct gttgcatttt ccaaatcttc
    16981 ttctgtaaca cctttattta taacatctct aagtctttga gttcctgctt ctggagcaaa
    17041 agtaagtcca gattttctta cttgttgtat tttatcagca atttccattg aaaaattatc
    17101 taatctaagg gatggaagcg aaatcccaat attattagat gcatattcat ctaccaaata
    17161 atcagtcaac tctgataact tactataatc actcgtacta agtgatgata atgatatttc
    17221 atcatatcca gtattcttaa ctaatttatc taatatttct ttaagtcttt taacactctt
    17281 ttctcttatt ggcctgtata tcatacctgc ttgacagaat ctacatcctc tagtacatcc
    17341 tctaaataat tctagtacta ttctatcatg aacagtatct atataaggta ctattagttt
    17401 ttctggataa tctacagtct caacatcttt tattatcctt ttagtaggat ttttagtaat
    17461 cccttctcta ttaggagtta cactttgaac tgtaccatct tcattgtact tgacatcata
    17521 aaaacttggt atgtatactc cttctatgct agatatttta tataaaaaat cttctctagt
    17581 cgttttattt ttcttccatt ctttatactc atttactact tctaaattaa cctcttcacc
    17641 ttcacctaat attactacat ctacaaaatc tgctaatggt tcggaattat aagcacaagg
    17701 accaccaacc attataaatg ggtcttccaa agttctttct tcttttaata ttggtatatt
    17761 ggctaaatct aatatattta agatattagt gtatgaaagt tcatattgaa gtgtaaaagt
    17821 gacaaaatca aagtttgtta taggctctct tgactctaat gcaaataatg gtatactttt
    17881 ttctctcatt atattttcca tatcaactgc aggagaatac actctctcac aaaatacatc
    17941 ttcatcctta tttattacat catataatat atgactccct aagtgactca taccaacttc
    18001 atataaatct ggaaagcaat gtgcatatct tatcaattca ctattactag tatctttatg
    18061 aattgaattt atttcatttc caagatatct agcaggcttt tctacttttt ttaagatttt
    18121 tttcaagtct actttattca tttattaaaa ttcctccaaa caagctcttt atttttattc
    18181 t
//
LOCUS       DAYAOO010000084        17869 bp    DNA     linear   BCT 12-OCT-2024
DEFINITION  TPA_asm: Clostridioides difficile isolate ST8-SSI-h139-18
            SAMN40601845-rid21577343.denovo.084, whole genome shotgun sequence.
ACCESSION   DAYAOO010000084 DAYAOO010000000
VERSION     DAYAOO010000084.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN40601845
            Sequence Read Archive: SRR28438827
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 17869)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 17869)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-MAY-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-MAY-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002157583.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002157583.1
            Genome Coverage       :: 163x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/11/2024 16:19:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 4,038
            CDSs (total)                      :: 3,963
            Genes (coding)                    :: 3,930
            CDSs (with protein)               :: 3,930
            Genes (RNA)                       :: 75
            rRNAs                             :: 6, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 60
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 33
            CDSs (without protein)            :: 33
            Pseudo Genes (ambiguous residues) :: 0 of 33
            Pseudo Genes (frameshifted)       :: 7 of 33
            Pseudo Genes (incomplete)         :: 25 of 33
            Pseudo Genes (internal stop)      :: 11 of 33
            Pseudo Genes (multiple problems)  :: 8 of 33
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..17869
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN40601845-rid21577343.denovo.084"
                     /isolate="ST8-SSI-h139-18"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Denmark"
                     /collection_date="2018"
                     /collected_by="Statens Serum Institute"
     gene            209..3754
                     /locus_tag="ACGI5H_003062"
     CDS             209..3754
                     /locus_tag="ACGI5H_003062"
                     /EC_number="2.7.7.65"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902211.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diguanylate cyclase"
                     /protein_id="HFG9698758.1"
                     /translation="MNRLKPRILGISILFIIIIILTCGAVFKFKFKLDNKLKETTHTY
                     LSEFTEHNIINLKTRLSGQFDMLESIANFIGNLNNINDEMVIDLMDSDVKRSSLIRMT
                     ISTLDGECYSNDGITHNVQDRDYFKKAKNGEKNISEPLKSIVNNKEIIVLSTPVYKSG
                     KIVGVLSGIYDSKKLNELLGLSAFDEKADVFVAKKNGDIVAQKTNKNRKTLSCIFQLF
                     DKDNCDEDDCLKTIKENMKNDKSGYFNYNLDNEKFMLNYQPLGVNDWYVFSVVPNKIV
                     SIQSENISYDVYIFALEILLVILIFIIYIACIINNNTKIIINEKEKFKVLTDNILGGV
                     KTCLKDEYMTMTYVSQGFLELTGYSCEDLNKIFKNRFKDMIYKDDLDKFNCIILNQLE
                     KQDKIEVEYRIVRKDGSIIWILERSKSINDNKGSECIQGVLTDITELKKIQEELDSKR
                     FEIQAINDSIVGGIVITEINDDFDSIYLNEGYLNMIGYTRKQLEDELNNKLIKLIFKD
                     DRTELINSINKQLKLSDTFASEQRVEKRDGTIIWILLKGRKMIYDNGKSVLCCVIVDI
                     TSAKLLEQELKKSEERHEIILKQTQNIIIEWDIEKDKMNISPNWYNKFKYDPITENAT
                     KNIIKSVDIYHDDMDKFISLIKLTSQGSEYEECEIRLRTRDTIYAWFSIKATTLFDNN
                     GKPYKVVGSLTDIDESKREAEKLKERAEKDPLTDLYNKKASQSLIEEYITLDKKRKGA
                     LMIIDIDDFKGINDNLGHLYGDAVLSEIANDLINLFRATDIVGRIGGDEFIVFIKDIS
                     ETRDIINKAEELVKTFERSFLGKGRNYKISLSVGIAKFPQDGMDYMTLFRNADIALYS
                     AKGKGKNCYTLYDKKFDKVQYITNTRNAGDSDNVEMSFKEHITNYIFDILYESSDIEV
                     AVNLILSIVGKHFNVSRMYIFENSDDNRVCKNTFEWCNEGVTSEINNLKNICYKDLGN
                     YLLNFNADGLFYCNDIENLGSDVKKVLKPQGIRSILQCKILEGNEFRGFIGFDECSYN
                     RMWTNDEVNTLTFISKTLSMFLLKMRIQSKLEESLTIQKSVMDNMDIWAYVVDRNTYE
                     LLFINKKMLESAPNTHVGDLCYKAIWNNQDKPCKKCPMIYLKDGDDTYKSFMHNKKFE
                     VQANITTTTLKWFDGKDACLIFGSEITSIEAEENT"
     gene            3939..5873
                     /locus_tag="ACGI5H_003063"
     CDS             3939..5873
                     /locus_tag="ACGI5H_003063"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418706.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:1904047 - S-adenosyl-L-methionine binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="YgiQ family radical SAM protein"
                     /protein_id="HFG9698759.1"
                     /translation="MENKFLPISKQDMIDRGWEELDFVLVTGDAYVDHHSFGTAIISR
                     VLESAGYKVGIIAQPDWRTTDDFMKLGKPRLAFLVNAGNMDSMVNHYSVSKKHREKDM
                     YSPGGKMGYRPDRATIVYCNKIREAYSDVAIVIGGIEASLRRFAHYDYWSDKVRKSML
                     IDSGADLLVYGMSEKQIVEVANALNDGYDPKYIRHIDGTCYISDTLEEIYDKYILIPS
                     YKEICEDKMKYVEAFKIQYDEQDPFRGNIIVQPHGSKYLVQNKPEKPLSREELDEVYG
                     LPYQKTYHPVYEKFGGIPAIEEVKFSIVSSRGCFGSCSFCAITFHQGRAVQSRSEKSI
                     IDEAIGITNLDDFKGYIHDVGGPTANFRRPACKKQITKGACKNRQCLSPSPCKNLDAD
                     HSEYLHLLRAVRKLPKIKKVFVRSGIRYDYVMADKNNKFLRELIEHHVSGQLKVAPEH
                     ISEEVLKYMQKPAGKTYDKFRQKFFAINEELGKKQYLIPYLMSSHPGSTLNSAIELAE
                     YLRDTHYQPEQVQDFYPTPGTLSTTMFYTGIDPLTMKPVYVPKSKRDKAMQRALLQYR
                     APRNYDLVYSALVEAGREDLIGFGHRCLIKPKNEKPYFNRNNSKKNVSKGTNKNKKTN
                     TNNRSNKNQQKSSTKKKKKH"
     gene            5979..6974
                     /locus_tag="ACGI5H_003064"
     CDS             5979..6974
                     /locus_tag="ACGI5H_003064"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728699.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MqnA/MqnD/SBP family protein"
                     /protein_id="HFG9698760.1"
                     /translation="MKKYISIILLVVLTMVVLVGCSPGKDNPKNKELSVVKQVKVAVP
                     DGLPAVAIAKLANENPEIKEGYETVYSIEKTPEAISTRVMKKDADIAIVPSNMAAIAY
                     NKTSSYNIVGTVGMGSLYLVSTENIKDYSDLVGKEVGCTGKGLTPDITIKSLLLQKDI
                     NYSDIKFNYVNSASELVPLLATGKVKTGIVPEPALSALMSKNPDIKIIKSLNDSWKEV
                     SGSKDGYPQSTLIVKSEFLRDNKDFVDSFVGQLSNSIDWANKNPEELGAYSEKIKIST
                     ESKIIGKSLERANLKYIPVKDMIKDYKNYYEKLANFDDKTLGGKVPDEAIYFVEK"
     gene            6946..7731
                     /locus_tag="ACGI5H_003065"
     CDS             6946..7731
                     /locus_tag="ACGI5H_003065"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418708.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HFG9698761.1"
                     /translation="MKQYTLLRNKKNKEQFIDKMEVTLSCVILLFLWQIIALKIDNDI
                     FLPTVGQVFNSIKEIMLNSSFYIDILYSMGRCFFSFLLAMIFAIILSIVSYLNRFFRN
                     LLKPINALTRSIPTMILVVLALIWFEKDSTPFIVGFTIVFPILYDNVLGAILNIDKNL
                     LEMANVYKIRFIDKVLKIYLPAIKFQIISILVSTFSLSLKVAIAGEVYSQPTYGIGTM
                     IQTEKINFNTSGIFAWIIIVLLISAILQIAQKFLARRAFLWKR"
     gene            7719..8417
                     /locus_tag="ACGI5H_003066"
     CDS             7719..8417
                     /locus_tag="ACGI5H_003066"
                     /EC_number="7.6.2.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437066.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HFG9698762.1"
                     /translation="MEKIKLSIENINKRYDSRIIFRDFNIDFYVNEVNCILGKSGCGK
                     TTLLNIISGIIKNDTNNLNIKENLNRVGNKLEASYIFQDDRLIDWLTVEENIKIVVNK
                     YYNKTQLNKICDEYLELVGISDYKKFYPQMLSGGIRQRVNIARAFIYPSKNIIMDEPF
                     KSIDAKNTQLIMDNFRNILRKEKRTVLFVTHNIEEALFLADRIFILGDSPIRIKKILK
                     NSKELEKNEVLKLI"
     gene            8540..9013
                     /gene="ybaK"
                     /locus_tag="ACGI5H_003067"
     CDS             8540..9013
                     /gene="ybaK"
                     /locus_tag="ACGI5H_003067"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418711.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0002161 - aminoacyl-tRNA editing activity
                     [Evidence IEA];
                     GO_process: GO:0043039 - tRNA aminoacylation [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Cys-tRNA(Pro) deacylase"
                     /protein_id="HFG9698763.1"
                     /translation="MVKTNAMRILDSNKIDYKVMSYEVKSEHVDGVEVAHDIGRDVNE
                     VYKTLVTQGVSKNIYVYVIPVHENLDLKKAAKVAKEKSVEMIHVKDINKLTGYIRGGC
                     SPIGMKKFYKTFVNESAKNLDTIIVSAGKIGYQIELSPFDLQRLIKVEFVDVIKK"
     gene            9210..10049
                     /locus_tag="ACGI5H_003068"
     CDS             9210..10049
                     /locus_tag="ACGI5H_003068"
                     /EC_number="4.2.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418713.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016829 - lyase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="fumarate hydratase"
                     /protein_id="HFG9698764.1"
                     /translation="MRKIKSEQIVEQVKKLCIEASLYLGEDVLSCIKEKAKSEKSEVG
                     KNILNILVENAEIAKEKNIPICQDTGMAVFFVEIGQEVLIEGDTLTDAINEGVRQGYE
                     EGYLRKSVVSPINRVNTKDNTPAVIHYDMVKGDKIKIEFAAKGFGSENMSKMKMLKPS
                     DGLEGIKKFIIDTVSEAGPNPCPPMVIGVGIGGTVDKCAQIAKKALFRELGEFNKDEN
                     IAKLESELLTAINKLGIGPQGLGGTTTALGLNIETFPTHIAGLPVVVNINCHASRHKN
                     VVI"
     gene            10062..10610
                     /locus_tag="ACGI5H_003069"
     CDS             10062..10610
                     /locus_tag="ACGI5H_003069"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418715.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016836 - hydro-lyase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Fe-S-containing hydro-lyase"
                     /protein_id="HFG9698765.1"
                     /translation="MIKITTPVNEIDIAKLNCGDTISLSGILYTARDAAHKRLIDCIN
                     KGEELPFDVYGQGIYYVGPTPTKPGEVIGAAGPTTSYRMDDLTIPLLERGLRLMIGKG
                     KRSDEVIEGMQKYGAVYLAAIGGAGAYISNSIKSCEIIAYEDLGAEAIRKIVVEDLKL
                     TVAIDSYGNNIYEQGRAIYECK"
     gene            10676..11857
                     /locus_tag="ACGI5H_003070"
     CDS             10676..11857
                     /locus_tag="ACGI5H_003070"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728698.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADP-dependent malic enzyme"
                     /protein_id="HFG9698766.1"
                     /translation="MSKDYAKLALEMHEINKGKVSVESKVEIKTKDDLSTAYTPGVAE
                     PCLKIHENQDDVYRYTSKGNLVAVVSDGSAVLGLGNIGAEASIPVMEGKAILFKQFAD
                     VDAFPICLKTNDVDEIVKSVELMEPVFGGINLEDISSPRCFEIEERLKKSLSIPVFHD
                     DQHGTAIIVAAAIINSIKLIENKKIEDLEIVINGAGAAGIAIAKILLNMNVKNIILCD
                     RSGALEASIENLNYVQKEMLKVTNIRNEKGPLKDIIKGKDVFIGVSGPGAVTKEMVES
                     MSEKPIILAMANPTPEIMPEEAKLGGAFIMGTGRSDFPNQVNNVLAFPGIFRGALDVK
                     AKEINEEMKIAAAYAIANTISDEEICPEYILPDVFNKNVVKNVAKAVKEAAIKTKVNR
                     I"
     gene            12149..12538
                     /locus_tag="ACGI5H_003071"
     CDS             12149..12538
                     /locus_tag="ACGI5H_003071"
                     /EC_number="2.3.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905209.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016747 - acyltransferase activity,
                     transferring groups other than amino-acyl groups [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HFG9698767.1"
                     /translation="MMEYKVNDQELNASMFIPFVNRIWPGDYDMDKTQTALSKTLNIT
                     AYDDKVLVGCLRVLSDGYYFGTITELLVLPEYQKQGIGSKLFQLAKENTPTMLYFGAQ
                     PGVEAFYEKNGCQRSLQSYIIKKKDSY"
     gene            12688..12951
                     /locus_tag="ACGI5H_003072"
     CDS             12688..12951
                     /locus_tag="ACGI5H_003072"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418727.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc ribbon domain-containing protein"
                     /protein_id="HFG9698768.1"
                     /translation="MEETKFCQCCAMPMGQTDELYGTNKDGSKSTDYCSYCFKDGEFT
                     ADISMEEMIEVCIPHMLQSNKDMTEDEARTMMNNFFPTLKRWK"
     gene            complement(13080..13922)
                     /locus_tag="ACGI5H_003073"
     CDS             complement(13080..13922)
                     /locus_tag="ACGI5H_003073"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S1-like domain-containing RNA-binding protein"
                     /protein_id="HFG9698769.1"
                     /translation="MINIGDFNKLTVKRKTEFGYFLDGQTNNTKDDILLHNRLIGKNE
                     INIGDEVNAFIFKDSDDRTAATLIPPLAKVGDVAHLKVVDNTDIGTFIDMGLPKDILV
                     PFKAKTYPLFRDEKYLFYIYLDKSKRIAATTDIDSYLLTDHTYNVGDIVTGVVYGFQT
                     NNSAMICVDNKYAGVILHNEYFTELKTGDVLENLHVIKIYEDGKLGLSPRGNRKDELD
                     TLENKILSYLEGSDGYMRFNDKSDPKDISILFNSSKKNFKRALGVLMKKGLIYQDEEG
                     TYLK"
     gene            14217..14951
                     /locus_tag="ACGI5H_003074"
     CDS             14217..14951
                     /locus_tag="ACGI5H_003074"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437044.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HFG9698770.1"
                     /translation="MKIVNKSSNIPLHTQLSSIIREMIETGELKEGDAIMPERELCNI
                     QNVSRMTVNKTIVGLVTEGLLYRVQGKGTFVAKQKKKYQFSNVKGFTDVMKEKGVNIK
                     TDILSFEMELPDDLVKRKLGISDNTTNIYKIVRLRYTDGEPFGLEIVYLSEEMCKGLT
                     KGILDNSSLYRVLNEKYGYKIQKAEQVMEPVILSDEESKLLETDEGALALKLHRNSYN
                     REGSPIEYTISIFRTDKYQYEIVLSE"
     gene            14961..16094
                     /gene="nagA"
                     /locus_tag="ACGI5H_003075"
     CDS             14961..16094
                     /gene="nagA"
                     /locus_tag="ACGI5H_003075"
                     /EC_number="3.5.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861065.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008448 - N-acetylglucosamine-6-phosphate
                     deacetylase activity [Evidence IEA];
                     GO_process: GO:0006044 - N-acetylglucosamine metabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylglucosamine-6-phosphate deacetylase"
                     /protein_id="HFG9698771.1"
                     /translation="MKCLINGKIILKNQILENKVLVFDEKIIDIADSVPKDCEVIDAD
                     GKYISPGLIDIHIHGNMGKDTMDSTDESIETISKSIMRHGVTSFLPTTMTMDKEHVYD
                     ALEVIKKAQNRKLEGAQVLGAHLEGPFINENYKGAQNEKFIINSKYEFIKEYKDVIKV
                     ITYAPEKDIDFDFTREIKRCTDIVLSIGHSNANYDQAKEAINLGVTNVTHMFNAMTGL
                     NHRDPGVVGAALTTNVYSELIADTIHINKDLFQFILNNKGKERLILITDSIEAGGLED
                     GNYSLGGQKVIVKGNEARLENGALAGSVLSLNKMVFNFLDNTNLKVNEAINLASLNPA
                     TSLGINDKKGSLEIGKDADIAVFDENLDCKMTLCLGDVVYKNI"
     gene            16193..16942
                     /gene="nagB"
                     /locus_tag="ACGI5H_003076"
     CDS             16193..16942
                     /gene="nagB"
                     /locus_tag="ACGI5H_003076"
                     /EC_number="3.5.99.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437039.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004342 - glucosamine-6-phosphate
                     deaminase activity [Evidence IEA];
                     GO_process: GO:0006044 - N-acetylglucosamine metabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glucosamine-6-phosphate deaminase"
                     /protein_id="HFG9698772.1"
                     /translation="MRVLVCKDYDGMSKKAAEMIAAQIVLKPNSILGLATGSTPVGMY
                     RDLVKKYNDNIVDFSDVMSFNLDEYYKLPISNDQSYDYFMKENLFNHVNIKPENTHLP
                     NGMADDIEKECMNYEASIDAAGGIDVQVLGIGRNAHIGFNEPDTKFAKRTHVVELTES
                     TIEANARFFKSREDVPKKAVSMGIGSILKSKKILLLASGEEKADAVYNTVYGDITPEV
                     PGSILQLHKDTIVIVDEAAASKLNPKDYKLV"
     gene            17117..17389
                     /locus_tag="ACGI5H_003077"
     CDS             17117..17389
                     /locus_tag="ACGI5H_003077"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9698773.1"
                     /translation="MLKIIMFSGILSSIIKLPIIGILPTGNIKKNTGISDSKKDGKQR
                     RSNLGISIYQLPSFLYSLINNSVPSNKPIPPEEIKLIKMYLLKSCI"
BASE COUNT         7154 a         1886 c         3139 g         5690 t
ORIGIN      
        1 aaagttataa tttttaatat taattaagaa tgatgaaata tgaataaaga ttttacaaat
       61 aaatcttaag ctatcttatt taattctaat acaggaagaa ggtaaatgta tattgaaaaa
      121 atcatagaaa tagaagtaaa caatttaaat aaatacaaag gtttgcaaaa gaagtaatat
      181 aattatatac aatgaggatg tgagtatgat gaacagacta aagccaagaa ttttaggtat
      241 tagtatcttg tttattatta taattatttt aacatgtgga gctgttttca agtttaaatt
      301 taaattagat aataaattaa aagaaaccac acatacatat ttgtctgagt ttacagaaca
      361 caatataatt aatctcaaga caagacttag tggtcaattt gacatgcttg aatctattgc
      421 taacttcata ggaaacttga ataatataaa tgatgaaatg gtgattgatt taatggattc
      481 tgatgtaaag cgaagttctt taattagaat gactatctct acattagatg gggaatgtta
      541 ttctaatgat ggaattaccc ataatgttca agatagagat tattttaaaa aagctaaaaa
      601 tggagaaaag aatatatcag agcctttaaa atctattgtt aataataaag aaataatagt
      661 tttatctacc ccagtttata aaagtgggaa aatagttggt gttttaagtg gaatttatga
      721 ttcaaaaaag ttaaatgagt tattaggatt atctgcattt gatgaaaaag cagatgtttt
      781 tgttgcaaag aaaaatggag atatagttgc tcaaaaaaca aataaaaata gaaagacgct
      841 atcatgtata tttcagcttt ttgacaaaga taattgtgat gaagatgatt gtctaaaaac
      901 tataaaagaa aatatgaaaa atgataagtc tggatatttt aattataact tagataatga
      961 aaaatttatg ttaaactatc agccacttgg agttaatgat tggtatgttt tttctgttgt
     1021 gccaaataaa atagtatcta ttcagtcaga gaatatatct tatgatgtat atatttttgc
     1081 attagaaata ctactagtta tattgatttt tataatatat atagcatgta ttataaataa
     1141 taacaccaaa attattataa atgaaaaaga aaaatttaaa gtactcactg ataatatatt
     1201 aggaggggtt aaaacctgtt taaaagatga atatatgact atgacatatg taagtcaggg
     1261 gtttttagag cttacaggtt actcttgtga agatttaaat aaaatattta aaaatagatt
     1321 taaagacatg atttataaag atgatttaga caagtttaat tgtattattc taaatcaatt
     1381 agaaaaacaa gataaaattg aagttgaata tagaattgta agaaaagatg gaagtataat
     1441 ttggattttg gagagaagta agtctataaa tgataataaa ggaagtgagt gtattcaggg
     1501 agttttaact gatataacag aacttaagaa aatacaagaa gaattagatt caaaaagatt
     1561 tgaaatacag gctatcaatg atagtattgt tggtggaata gtgataactg agataaatga
     1621 tgattttgat agtatatatt taaatgaagg ttatttaaat atgattggat atacacgcaa
     1681 acaactggaa gatgagctaa ataataaatt aatcaaactt atttttaaag atgatagaac
     1741 agaattaatt aatagtataa acaaacaact caaattaagt gatacatttg catctgaaca
     1801 aagagttgaa aaaagggatg gcactattat atggatttta ttaaaaggaa gaaagatgat
     1861 ttatgataat ggaaaatctg tactttgttg tgttattgta gatattactt ctgctaaatt
     1921 attagagcaa gaacttaaaa agagtgaaga acgtcatgaa atcattctaa agcagacgca
     1981 aaatattata atagaatggg atatagaaaa agataaaatg aatatatcac ctaattggta
     2041 taataagttt aaatatgacc ctataactga aaacgcaaca aaaaatataa ttaaatcagt
     2101 agatatatat catgatgata tggataagtt tatttcatta attaaactta cttcacaagg
     2161 tagtgagtat gaagagtgtg aaattagact tagaactaga gatactattt acgcttggtt
     2221 tagtataaag gcaacaactt tatttgataa taatggtaaa ccttataaag tagtaggaag
     2281 tttgactgat attgatgaat caaaacgaga agctgaaaag ttgaaagaaa gggcagaaaa
     2341 agaccctctt acagatctgt ataataaaaa agcatcacaa tcacttatag aggagtacat
     2401 aacattggat aaaaaaagaa aaggtgcttt aatgattatt gatattgatg actttaaagg
     2461 aataaatgat aatttaggac atttatatgg ggatgctgta ttaagtgaaa ttgcaaatga
     2521 cctaataaat ctatttagag caaccgatat agtaggcaga attggtggag atgagtttat
     2581 tgtatttata aaagatattt ctgaaacaag agatattata aataaagcag aagaattggt
     2641 aaaaacattt gaaaggtctt ttttaggtaa aggacgaaat tataaaatat cattaagtgt
     2701 aggaattgct aagtttccac aagatggtat ggactatatg acactattta gaaatgcgga
     2761 tatagctctt tactcagcca aagggaaggg caagaattgt tatacattgt atgataaaaa
     2821 atttgataaa gtccaatata taactaatac aagaaatgca ggagatagtg ataatgtaga
     2881 gatgtctttt aaagaacata tcacaaatta tatatttgat atactatatg aatcaagtga
     2941 tatagaagtg gcagtaaatt taattctaag tattgtaggt aaacacttta atgtgagtcg
     3001 catgtatata tttgaaaatt cagatgataa tcgagtatgt aaaaatacat ttgaatggtg
     3061 taacgaaggt gtaacctcgg aaattaataa tcttaaaaat atttgttaca aggatttagg
     3121 caactatctt ttaaatttta atgcagatgg gttattttat tgtaatgata ttgaaaattt
     3181 aggtagtgat gtgaaaaaag tacttaagcc acaaggcata cgttcaatat tacaatgtaa
     3241 aattttagag ggtaatgaat ttagagggtt cataggattt gatgaatgtt catataatcg
     3301 tatgtggact aatgatgaag tgaacacttt gacatttata tctaaaacgc tcagtatgtt
     3361 tttattaaaa atgcgtattc agagtaagct agaagagtct ttaacaattc aaaaatctgt
     3421 gatggataat atggatatat gggcatatgt tgttgacagg aatacctatg aattactatt
     3481 tatcaataaa aaaatgcttg agtcagcacc aaacactcat gtaggtgatt tatgttataa
     3541 agcgatatgg aataatcaag ataaaccttg taaaaaatgc cctatgatat atttaaaaga
     3601 tggtgatgat acttataaat cattcatgca taataaaaag tttgaggtac aggcaaatat
     3661 aactacaact actttgaaat ggtttgatgg taaagatgca tgtttaatat ttggaagtga
     3721 aataactagt attgaagctg aagaaaatac ttaaaatact gtgttatata tatacttaaa
     3781 atcgcaattt gaatttatta gacttaaaat gtctatataa atcatttaag ttgtggtttt
     3841 aagtattttt tatgatataa ttaagcgtta agaacaaaat taaaagatac ttttgtataa
     3901 aaaaatattt gttaaatata tattgagcag gtgataatat ggaaaataag tttttaccaa
     3961 taagcaaaca agatatgata gatagaggat gggaagaatt agattttgtt ctagttacag
     4021 gagatgctta tgtggaccat catagttttg gaacagcaat aatatctaga gttttagaaa
     4081 gtgctgggta taaagttgga ataatagctc aaccagactg gagaactaca gatgatttta
     4141 tgaagctagg aaaacctaga cttgcatttc tagttaatgc aggaaatatg gattcaatgg
     4201 tcaatcatta ttctgtaagt aaaaagcata gagaaaagga tatgtattct ccaggtggga
     4261 aaatgggtta tagaccagat agagctacta tagtatattg caataaaata agagaagcat
     4321 acagtgatgt tgcaatagta ataggtggaa ttgaagcgag cttaagaaga tttgcacact
     4381 atgattattg gagtgataag gttagaaagt ctatgttaat agatagtgga gcagatttat
     4441 tagtttatgg tatgagtgaa aagcagattg tagaagtagc caatgcactt aatgatggat
     4501 atgacccaaa atacattaga catattgatg ggacatgcta tatttcagat acattggaag
     4561 aaatatatga taaatatata ttaattccat catataaaga aatttgtgaa gataaaatga
     4621 agtatgtaga agcttttaaa attcaatatg atgagcaaga cccatttaga ggtaatataa
     4681 ttgttcaacc tcatggaagt aagtatctgg ttcaaaataa gccagaaaaa ccacttagta
     4741 gagaagaatt agatgaagta tatggattac catatcagaa gacataccat cctgtatatg
     4801 aaaaatttgg aggaatacca gctatagaag aagtaaaatt tagtatagta agttcaagag
     4861 gctgttttgg tagttgttca ttttgtgcaa taacatttca tcaaggtaga gcagtgcaaa
     4921 gtagaagtga aaaatcaatt attgatgaag caataggaat aacaaattta gatgatttta
     4981 aagggtatat acatgatgtt ggaggtccaa cagctaattt tagaagacca gcatgtaaaa
     5041 aacaaattac taaaggtgct tgtaaaaata gacaatgctt atctccatca ccatgtaaaa
     5101 atttagatgc agaccacagt gaatacttac atttacttag agctgtaaga aaattaccta
     5161 aaataaaaaa ggtgtttgtg cgttctggaa ttagatacga ttatgtaatg gcagataaga
     5221 acaataaatt tcttagagag ttgatagagc atcatgtaag tggtcagtta aaggtagccc
     5281 cagaacatat atcagaagaa gttttaaagt atatgcaaaa accagcagga aaaacttatg
     5341 ataaatttag acagaagttt tttgctataa atgaagaatt aggtaaaaag caatatttga
     5401 taccctattt aatgtctagt caccctggtt ctaccttaaa tagcgctata gagttagcag
     5461 agtatttaag agatactcac taccaaccag agcaggttca ggatttttat ccaactccag
     5521 ggactctatc tacaaccatg ttttatacag gtattgaccc gcttacaatg aagccagttt
     5581 atgttcctaa atcaaaacgt gacaaggcaa tgcaaagggc tttattacaa tatagagcac
     5641 ctagaaatta tgatttggta tactctgcgt tagttgaagc aggaagagaa gacttaattg
     5701 gttttggaca tagatgtctt ataaagccaa aaaatgaaaa gccttatttt aatagaaata
     5761 attctaaaaa aaatgtatct aaaggaacaa ataaaaacaa aaaaactaat acaaataaca
     5821 gaagtaataa aaatcaacaa aaaagttcaa ctaaaaaaaa gaaaaaacat taaagtataa
     5881 ataaaaatac ttaaaaaaga aggattattc gataaattaa cagaaattag tataaataaa
     5941 tataattatt ttaatgacgt tacctttggg aggaagagat gaaaaagtat atttctataa
     6001 tattattagt ggtgttgact atggttgttt tggtaggatg ttcaccagga aaagataacc
     6061 ctaaaaataa ggagctatca gttgtcaaac aagtaaaagt agctgttcca gatggactac
     6121 cagcagtggc aatagctaaa cttgcaaatg aaaatccaga gattaaagaa ggatatgaaa
     6181 cagtgtatag cattgaaaag acacctgaag cgatttccac tagagtgatg aaaaaagatg
     6241 cagatatagc tatagttcct tcaaacatgg ctgcaatagc gtataataaa acttcatcat
     6301 ataatattgt tggaactgta ggaatgggtt cactttattt ggtgtcaaca gaaaatataa
     6361 aagattactc tgatttagtt ggtaaagaag ttggatgtac tggaaaagga cttactccag
     6421 acataactat aaaaagtctt ttgttacaaa aggatataaa ttattcagat ataaaattta
     6481 attatgtaaa ttcagcaagt gaactggtac cattattggc tactggtaaa gttaaaacag
     6541 gtattgttcc agaacctgca cttagtgctt tgatgtctaa aaatccagac ataaaaatta
     6601 taaaaagttt aaatgactca tggaaggaag taagtggttc aaaagatggt tatcctcaat
     6661 ctactttaat tgtaaagtct gaatttttaa gagataataa agattttgtt gattcttttg
     6721 taggtcaatt atcaaatagt atagattggg caaacaaaaa tcctgaagaa ttaggtgcat
     6781 attctgaaaa aataaaaata tctactgaat caaagataat aggaaaatct cttgaaagag
     6841 ctaatttgaa atatattcca gttaaggaca tgattaaaga ttataaaaat tactatgaga
     6901 aattagctaa ttttgatgat aagacattag gaggcaaagt accagatgaa gcaatatact
     6961 ttgttgagaa ataaaaaaaa taaagaacaa tttatagata aaatggaggt aacactttct
     7021 tgtgttatcc tcttattttt atggcaaatt attgctttaa aaattgataa tgatattttt
     7081 ttaccaacag taggtcaagt gtttaatagt ataaaagaga ttatgctaaa ttctagtttc
     7141 tatatagata tactttactc tatggggaga tgttttttta gttttttact ggctatgatt
     7201 tttgctatta tactttcaat agtgtcttat ttaaatagat tttttagaaa cttattaaag
     7261 ccaatcaatg ctttgacacg ttcaatacca actatgatat tggtagtact tgcacttatt
     7321 tggtttgaaa aggatagtac cccttttata gttggattta ctatagtttt tcctatattg
     7381 tatgataacg ttttgggcgc tatattgaat atagacaaga acttattaga aatggctaat
     7441 gtgtataaaa taaggtttat agataaggtg ttaaaaattt atttaccagc cataaaattt
     7501 caaattatat ctatactagt atcaacattt tctttaagtt tgaaagttgc tatagcagga
     7561 gaggtgtata gtcaacctac atatggtatt ggaactatga tacagactga aaaaattaac
     7621 tttaacacat ctggaatatt tgcatggata attattgttc ttttaatatc tgctatttta
     7681 caaatagctc aaaagttttt agcaaggaga gcttttttat ggaaaagata aagttgagta
     7741 ttgaaaatat aaataaaaga tatgatagtc gtattatatt tagagatttt aatattgatt
     7801 tttatgtaaa tgaggtaaat tgtatccttg gaaaatctgg ttgtggaaaa actacactct
     7861 tgaacataat aagtgggatt attaaaaatg acaccaacaa tctaaatatc aaagaaaatt
     7921 taaatagagt aggaaataag cttgaagcta gttacatatt tcaagatgat agacttatag
     7981 actggttaac agtagaagaa aatataaaga tagttgtaaa taaatactat aataaaactc
     8041 aattaaataa aatttgtgat gaatacttgg aattggttgg aattagtgat tataaaaaat
     8101 tctatcctca aatgcttagt ggaggtatta gacaaagagt aaatattgct agagctttta
     8161 tatatccatc aaaaaacatt ataatggatg aaccttttaa atctattgat gcaaagaata
     8221 cacagcttat aatggataat tttagaaata tattaagaaa agaaaagaga actgtgttat
     8281 ttgtaactca taatattgag gaagcattgt ttttagcaga taggatattt attttaggag
     8341 actctccaat tagaataaaa aaaatattaa aaaattctaa ggaattggaa aaaaatgaag
     8401 ttttgaagtt gatatagagt tataataata ctgtcgtttt aaaatatatt tggttaaaat
     8461 ctataagact atattaaaat agtacagaat attcaaaact gtgtataatg ttcgtatttt
     8521 ataaaaagga agtgaatgta tggttaagac taatgctatg agaatattag attcaaataa
     8581 gattgattat aaagtaatgt cttatgaagt gaaaagtgaa catgtggatg gtgttgaggt
     8641 ggcacatgat ataggaagag atgtaaatga agtgtataag acattagtaa ctcaaggagt
     8701 tagtaagaat atatatgtat atgtaatacc agtacatgaa aacttagact taaaaaaggc
     8761 tgcaaaagta gctaaagaga aaagtgtaga gatgattcat gtaaaagata taaataagct
     8821 tacaggttat attagaggcg gatgttctcc tataggtatg aaaaagtttt ataaaacttt
     8881 tgtaaatgaa agtgcaaaga atttagatac aattattgtg agtgcaggaa aaataggata
     8941 tcaaatagaa ctatctccat ttgatttaca aagacttata aaagtagaat ttgtagatgt
     9001 aataaaaaaa taagaattac atataaaata tagagcttat attctcaata ataggtgttg
     9061 taatattaat aaaatgaata agaattttaa aataaatatt cagttactta tgtgtaattg
     9121 gtataaaaat attgagaaat tttaaaaaca atggtaaagt gtaagtataa tcacgaatat
     9181 tttttataaa gtaatggagg gatgttcgct tgagaaaaat aaaatctgaa caaatcgtcg
     9241 agcaggtaaa aaaactttgt atagaagcga gcctatattt aggagaagat gttttaagtt
     9301 gtataaaaga aaaagcgaaa agcgaaaaga gtgaagttgg aaaaaatata ttgaatatat
     9361 tagttgaaaa tgctgaaata gctaaagaaa aaaatatacc aatatgccaa gatactggta
     9421 tggctgtatt ttttgttgaa ataggacaag aagttttaat tgaaggagac acacttactg
     9481 atgctataaa tgagggagta agacaagggt atgaagaagg ctacttaaga aaatctgttg
     9541 taagtccaat taacagagta aatacaaaag ataatacacc tgctgttatt cattatgata
     9601 tggtaaaagg tgataaaatt aaaatagaat ttgcagctaa gggatttgga agcgaaaata
     9661 tgagtaagat gaaaatgtta aagccatcag atggattgga aggaattaaa aaattcataa
     9721 tagatacagt ttcagaagct ggacctaacc catgccctcc tatggtaatt ggagttggta
     9781 taggtgggac tgtggacaaa tgtgctcaaa tagctaaaaa ggcacttttt agagaactag
     9841 gtgaatttaa taaggacgaa aatatagcaa aacttgaaag tgaactatta acagctatta
     9901 ataaacttgg tataggacct caaggcttag gtggtactac aacagctttg ggattaaaca
     9961 tagagacttt tcctacacac atagcaggtc tacctgttgt tgtaaatata aactgccatg
    10021 catcaagaca taagaatgta gtaatttagg aggaaaataa aatgataaaa ataactacac
    10081 ctgtaaatga aattgatata gcaaaattaa attgtggaga tacaattagt ttgagtggta
    10141 tactttatac agcaagagat gctgctcata aaagattgat agattgtata aataaaggtg
    10201 aagaattacc atttgacgta tatggtcaag gaatatatta tgtaggacct actcctacaa
    10261 agccaggaga agttataggt gctgcaggtc caacgacgag ttatagaatg gatgatttga
    10321 ctatacctct tttagaaaga ggtcttagat tgatgatagg caagggaaaa agaagtgatg
    10381 aagttataga aggtatgcaa aaatacggag cagtttatct tgctgcaata ggaggagctg
    10441 gagcgtatat ttcaaattca ataaaatcat gtgaaattat tgcatatgaa gatttaggag
    10501 ctgaagctat aagaaagatt gtagtagaag accttaagct tacagtagca atagatagct
    10561 atggaaataa tatatatgag caaggtcgag caatttatga atgtaaataa tgtttagaaa
    10621 taaatatgaa tatcaaaatt aaaaatagtt gtgtatattt taaggaggaa aattgatgtc
    10681 taaggattat gcaaaattgg cattagaaat gcatgaaatc aacaaaggga aagtaagtgt
    10741 agaaagcaag gtagaaatta aaactaagga tgatttatca acagcatata caccaggggt
    10801 tgctgaacct tgtttaaaaa tacatgaaaa tcaagatgat gtttatagat acacttctaa
    10861 agggaatcta gtagcagtag ttagtgatgg aagtgctgta cttggattag gtaacattgg
    10921 tgctgaagca tctatacctg ttatggaagg taaagctata ttatttaaac aatttgcaga
    10981 tgtagacgct tttccaatat gtttaaagac taatgatgta gatgagatag ttaaatctgt
    11041 agagttgatg gagcctgtat ttggaggtat aaatttggaa gacatatctt ctccaagatg
    11101 ttttgagata gaagagagat taaaaaaatc tttaagtata cctgtttttc atgatgacca
    11161 acatgggaca gcaataatag ttgcagccgc cataataaac tcaataaagt taattgaaaa
    11221 taaaaaaata gaagatttag aaatagttat aaacggagca ggagctgctg gtatagccat
    11281 agcaaagata ctacttaata tgaatgttaa aaatataatc ttatgtgata gaagtggagc
    11341 attggaagct agtatagaaa atctaaacta tgttcaaaaa gaaatgttaa aagtaacaaa
    11401 tataagaaat gaaaaaggac ctttaaaaga tattataaaa ggaaaagatg tatttattgg
    11461 tgtttcaggt ccaggagctg ttacaaagga aatggttgaa agtatgtctg agaagccaat
    11521 aatattggca atggcaaatc ctactccaga gataatgcca gaagaagcaa aattaggtgg
    11581 agcatttata atgggaacag gtcgttcaga cttccctaat caagtcaata atgtactggc
    11641 ttttcctgga atatttagag gtgcacttga tgttaaggct aaagagataa atgaagaaat
    11701 gaagatagct gctgcatatg caattgctaa tacaataagt gatgaagaaa tatgcccaga
    11761 gtatatatta ccagatgtat ttaataagaa tgtagtaaaa aatgttgcta aggcagttaa
    11821 agaagcagcg ataaaaacta aagtaaatag aatataaatt tttatatgtt catatatcct
    11881 tatattatcg ggtatatggg catttttatt ataggtttat actcatatat ccttactttt
    11941 atatacatat ctttatgatt aaaggtgtta gaaaatgtag taaattttat actatcagac
    12001 tctatcttta ttactttagt agatacatgg ttgtaaaggt ttatagaaaa aaatatagga
    12061 aggcagattt ttattgttgc gtatatatga gaatgatata atatgaatat tataaattaa
    12121 taaatttaaa tttatggagg tacaagagat gatggaatat aaagttaatg accaagaact
    12181 taatgcttca atgtttatcc cattcgtcaa caggatatgg ccaggagatt atgatatgga
    12241 taaaacacag actgcattat caaaaacttt gaatataact gcttatgatg ataaagtgct
    12301 tgtaggatgt ctgcgagttc tttcagatgg ttattatttt ggaacaatta cagaattgct
    12361 tgttcttcca gagtatcaga aacaaggcat tggtagtaag cttttccagc ttgctaaaga
    12421 gaacacccca actatgctat attttggtgc acagccagga gtagaagcgt tctatgaaaa
    12481 aaatgggtgc caaagaagtc tgcaatccta cataataaaa aagaaagata gttattaaag
    12541 ttccagcttt caataatctt aaaagtacaa tattttagtg gaatcatttc attttttatt
    12601 actaatatga cataaacatg tcatattagt attgatatac ttttaatatg gttaagagcc
    12661 aaagaaaaat ataaggagtg atttaaaatg gaagaaacta aattttgcca atgctgtgca
    12721 atgccaatgg gacaaactga tgaattatat gggacaaata aagatggaag taaaagtact
    12781 gattattgta gttattgttt taaagatggt gagtttacag ctgatataag tatggaagag
    12841 atgatagaag tttgtatccc tcatatgctt caaagtaata aggatatgac tgaagatgaa
    12901 gcaagaacaa tgatgaacaa tttctttcca acattaaaac gctggaaata attttatgca
    12961 aaattagtta tatgcaaaac atgaaatatg gtgttgagaa taaggggtgg tgtgctttat
    13021 agcataccac ctgttttgtt acttggagtt cagttatttt cctaaatatt ttaaatatac
    13081 tattttagat aagttccctc ttcatcttga taaattaatc cttttttcat aagcactcca
    13141 agagctcgtt taaaattttt cttacttgaa ttaaataata tagaaatatc tttagggtca
    13201 gatttatcat taaatctcat atatccatca gaaccttcta aataacttaa aatcttattt
    13261 tctaaagtat caagttcatc ctttctattt cctctaggag aaagaccaag ttttccatct
    13321 tcatatattt ttatgacatg taaattttca agaacatcac cagtttttag ttcagtaaag
    13381 tactcattat gaagtattac accagcatat ttattgtcta cacatatcat tgcagaatta
    13441 ttagtttgga atccatatac aactccagtt acaatatctc ctacattgta agtatggtct
    13501 gttaataagt atgaatctat gtctgtagta gcagcaattc ttttgctttt gtctaaatat
    13561 atataaaata aatatttttc gtctctaaat agtggataag tcttagcttt aaaaggaact
    13621 aatatgtctt taggaagtcc catatctata aaagtaccaa tgtctgtatt atcaactact
    13681 tttaaatgtg ctacatcccc aaccttagct aaaggcggta ttaaagttgc agcagttctg
    13741 tcatcagaat ctttaaatat gaaagcattt acttcatcac ctatgtttat ttcatttttt
    13801 ccgattaatc tattatgaag aagtatatcg tcttttgtgt tattagtttg tccatccaaa
    13861 aaatatccaa attcagtttt tctttttact gtaagtttat taaaatcacc tatgtttatc
    13921 aaattaaaat catcctctca ttttatattt ataatttagc cataatatac ttatgtagta
    13981 gtttgtcaca gtatccatat tagtattagt gaaatttaca ataaataata tagttattta
    14041 tgtatttttc aattctctag cttcttatat agtataaact ccaatttctt ttttgtcttt
    14101 aggttttatt aaaattttta caaaataagt taaaaagtat tgaaataaaa tttcttttaa
    14161 agtataattg gtatatacca aaattggtat ataccatatc gaaaagtggt gactatatga
    14221 aaatagtaaa taaatctagt aatataccat tgcatactca attaagttca ataataagag
    14281 agatgataga aactggtgag cttaaagagg gcgatgcaat aatgccagaa agagaacttt
    14341 gcaacataca aaatgtaagt cgtatgacag taaataaaac cattgttgga ttagttacag
    14401 aaggacttct ttatagggta caaggtaaag ggacattcgt tgcaaagcaa aaaaagaagt
    14461 atcagttttc aaatgtaaaa ggttttactg atgttatgaa agaaaaggga gtaaacataa
    14521 aaacggatat attatccttt gagatggaac taccagatga tttagttaaa agaaagcttg
    14581 gaataagtga taatactaca aatatatata agattgtcag acttagatat actgatggag
    14641 agccatttgg attagaaata gtatatctat cagaagaaat gtgtaagggt ctaacaaaag
    14701 ggatattgga taattcttca ttatataggg ttttaaatga aaaatatggc tataagatac
    14761 aaaaagctga acaggtaatg gagccagtaa tactttcaga tgaagaaagt aagcttcttg
    14821 aaacagatga aggtgcttta gctcttaaac ttcatagaaa ttcctataat agagaaggta
    14881 gccctataga atataccata tcaatattta gaacagataa atatcaatat gaaatagtat
    14941 tgagtgagta ggtgaataat atgaaatgtt taattaatgg aaagataata ttaaaaaatc
    15001 aaatcttaga aaataaagta ttagtatttg atgaaaaaat aattgatata gctgatagtg
    15061 taccaaaaga ttgtgaagtt atagatgctg atggaaaata tatatctcca gggcttattg
    15121 atattcatat acatggaaac atgggaaaag atacaatgga ttcgactgat gaatctattg
    15181 aaacaatttc aaagtcaatt atgagacatg gagtaacatc ttttcttcca actacaatga
    15241 ctatggataa agaacatgtt tatgatgcac ttgaagttat taaaaaagcc caaaatagaa
    15301 agcttgaagg ggcacaagta ttaggagcac atttagaagg accttttata aatgagaatt
    15361 ataagggagc acaaaatgaa aaatttataa taaattcaaa atacgaattt ataaaagaat
    15421 ataaagatgt tataaaagtt ataacttatg ctccagaaaa agatattgat tttgatttta
    15481 ctagagaaat aaaaagatgt acagatatag ttttatctat tggtcatagt aatgcaaatt
    15541 atgaccaagc taaagaagct ataaatttag gagtaactaa tgtaactcac atgttcaatg
    15601 caatgactgg tttaaaccat agagacccag gcgttgttgg tgcagcactt acaactaatg
    15661 tgtacagtga gttaatagca gatacaatcc atataaataa agatttattt caatttatac
    15721 taaataataa aggaaaagaa agactgattt taataacaga ttctatagaa gctggtggtc
    15781 ttgaagatgg caattattct cttggaggtc agaaagtcat agttaagggt aatgaagcta
    15841 gacttgaaaa tggagcatta gctggaagtg tgttgtcttt aaataaaatg gtatttaact
    15901 tcttagataa tacaaacctt aaagtgaatg aagcaattaa tttagcttct ttaaatccag
    15961 caacatcttt gggaataaat gacaaaaaag gaagcttaga aataggtaag gatgcagata
    16021 tagctgtatt tgatgagaat ttagattgta aaatgacact ttgcttgggg gacgtagtat
    16081 ataaaaatat atagtataca aaacaaacct taaagacagt aaaaacaata taaaaaataa
    16141 taaattaaac ttacattagt aaaagtagta gttaaaattt aggaggaata agatgagagt
    16201 attagtgtgt aaagattatg atggaatgag taaaaaagcc gctgaaatga tagcagctca
    16261 aatagtttta aaaccaaatt caatactggg actagctaca ggaagtacac cagtaggtat
    16321 gtatagagat ttagtaaaaa aatacaatga taatatagta gatttttcag atgtgatgag
    16381 ctttaattta gatgaatatt ataagttacc aatatctaat gaccaaagct atgattattt
    16441 tatgaaagaa aatctattta atcatgtaaa cataaagcca gaaaatactc atctaccaaa
    16501 tggaatggct gatgatattg aaaaagagtg tatgaactat gaagcttcta tagatgcagc
    16561 tggtggtata gatgtacaag tacttggaat aggtcgtaat gctcatatag gttttaatga
    16621 acctgatact aaatttgcaa agagaactca tgtagttgaa cttacagagt ctacaataga
    16681 agctaatgca agattcttta aatcaagaga agatgttcct aaaaaagctg taagtatggg
    16741 aataggttca atattgaagt ctaagaaaat attgctttta gcttcaggag aagaaaaagc
    16801 tgatgcagta tataatactg tttatggaga tataactcca gaagttcctg gttctatact
    16861 tcaacttcat aaagacacta tagttatagt agatgaagca gcagcaagta aattgaatcc
    16921 aaaagattat aaattagtat aagaatagaa tgtagtttaa gtaaaaaata gctatcattg
    16981 agtaatcaaa tttatttaat gatagctatt tttatttaaa ttttttactt ctttttattt
    17041 aaattagtta ttattgttta aattacttgc ttattacttt ttacgaaaac tcgttatcaa
    17101 gaagtatcca aataagatgt taaaaattat tatgtttagt gggattctat caagcataat
    17161 aaaattacct ataattggga tattaccaac tggaaacata aagaagaata caggcatcag
    17221 tgatagtaaa aaagatggaa aacaaagaag aagtaatctt ggaatatcaa tataccaact
    17281 accatccttt ttgtattctc taatcaataa ttcagttcct agtaataaac caataccacc
    17341 agaggaaatt aaattaataa aaatgtatct tttaaagtct tgcatataac cagtgtaaaa
    17401 ttgagtatag aaatcataat ttaatttaac agctaaaaaa tacataagca atagaatgat
    17461 taaaaataaa agatatctaa gagctttttt cattttaaat tctcccttca gaaatacttt
    17521 attcagtttt attttgttgg aatctgattt tatcatttag tttaagaaat ccataatatt
    17581 agtgaagaat gaaataagta ttatatatga ataaatattt ttagaattaa ggtgaattgt
    17641 agtgcttaat ataactataa tattaattgt ttgaatattc aataaaaagt ttgaaaaata
    17701 tcaattttga tataaactga ataaatacag ttgaatatta aattattatt ttatcaaaaa
    17761 tatgcaaagt actacacctt caaatatcac ctaaagtaat taaaaggcaa ttaaggtgaa
    17821 gtagttcaag tatttctaaa ataagtttaa taaattctat aataattta
//
LOCUS       DAYAOO010000085        17670 bp    DNA     linear   BCT 12-OCT-2024
DEFINITION  TPA_asm: Clostridioides difficile isolate ST8-SSI-h139-18
            SAMN40601845-rid21577343.denovo.085, whole genome shotgun sequence.
ACCESSION   DAYAOO010000085 DAYAOO010000000
VERSION     DAYAOO010000085.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN40601845
            Sequence Read Archive: SRR28438827
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 17670)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 17670)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-MAY-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-MAY-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002157583.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002157583.1
            Genome Coverage       :: 163x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/11/2024 16:19:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 4,038
            CDSs (total)                      :: 3,963
            Genes (coding)                    :: 3,930
            CDSs (with protein)               :: 3,930
            Genes (RNA)                       :: 75
            rRNAs                             :: 6, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 60
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 33
            CDSs (without protein)            :: 33
            Pseudo Genes (ambiguous residues) :: 0 of 33
            Pseudo Genes (frameshifted)       :: 7 of 33
            Pseudo Genes (incomplete)         :: 25 of 33
            Pseudo Genes (internal stop)      :: 11 of 33
            Pseudo Genes (multiple problems)  :: 8 of 33
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..17670
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN40601845-rid21577343.denovo.085"
                     /isolate="ST8-SSI-h139-18"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Denmark"
                     /collection_date="2018"
                     /collected_by="Statens Serum Institute"
     gene            complement(614..1348)
                     /locus_tag="ACGI5H_003078"
     CDS             complement(614..1348)
                     /locus_tag="ACGI5H_003078"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HFG9698774.1"
                     /translation="MNLAKGLDVLKISSNVFGEDKVMYIPVIYTEDDATLIDTGLPGQ
                     GDLIIDALNKSNTSFDKLKNIIITHHDIDHIGNINYLREKSKNNIKVYAYKSEISYIT
                     GEETPFKLYMLEQMVDKIDDKMLSMLNVMGLGFKSSYTKVDVSLDNHEKLNLGEEIEV
                     IHTGGHTRGHICLYLKESKVLIAGDLLQVENGELKPVDVMHSNKQELKDAIKNISNYD
                     IETIVFSHGGLYQRNIIGTLKNLIIE"
     gene            complement(2359..2997)
                     /locus_tag="ACGI5H_003079"
     CDS             complement(2359..2997)
                     /locus_tag="ACGI5H_003079"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003440185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-2 transporter permease"
                     /protein_id="HFG9698775.1"
                     /translation="MLIHLVKKDILIVKKYVLLILFIAIGIPLFTLWRLPPFAQILGF
                     VLSIIFSEFMLCQYLLLKESQYSKASVLLCSTPYPRRGLVQSKYVLFAMVFIYCTLVY
                     WIENLLIPQIGTFDLTYILIVLLISSIIYGVYMPIQYKLGYETTKFFFVVIIMASSFV
                     LPLTIAHSNFEIPFIYQYPSMIVNIVLFLLSLIILLASMFISIKIFSNKELV"
     gene            complement(3000..3857)
                     /locus_tag="ACGI5H_003080"
     CDS             complement(3000..3857)
                     /locus_tag="ACGI5H_003080"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860900.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HFG9698776.1"
                     /translation="MENILEVYNLNKTYTDFSLSNISFALPEDCITGFIGVNGAGKTT
                     TIRSILDVVKRDSGKIKIFGKDFDGNEKELKNRIGVVFDDSYFYEELSMAEMKSIIAP
                     SYDNWCEEDYQQNMKRFNLNPKQKIDTLSKGMKMKFALALALSHKAEFLIMDEPTSGL
                     DPLIRSQILDILTGYMKKCGRGVFFSTHITSDLDKIADMIVMIDNGRIILEREKDTLL
                     DEHRKVKGDIQFLNDEIKKLFLNLEITGYGFIGITSKINEVQKNMPDILIERPTIEDI
                     MLAYIERRE"
     gene            complement(3859..4233)
                     /locus_tag="ACGI5H_003081"
     CDS             complement(3859..4233)
                     /locus_tag="ACGI5H_003081"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888433.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HFG9698777.1"
                     /translation="MKVLISNTSDKPLYQQIKEQIKEAIFTEELKEGDAMPSIRNFAN
                     DLKVSILTIRRVYEELENEGFLTRQVGIGTFISTGNLEILRDSKRRIVEQKMADMIKD
                     AKALGITQIELQEMMDILYQED"
     gene            complement(5395..6585)
                     /locus_tag="ACGI5H_003082"
     CDS             complement(5395..6585)
                     /locus_tag="ACGI5H_003082"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860897.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="permease"
                     /protein_id="HFG9698778.1"
                     /translation="MSDMLLWFSVVLVLFAIGDLIASKTKAKVSAVFVTLLLFLILFV
                     TKAIPADIIEKAGMTAAASWSVPMIMFSMGTMLNVKQFIDEWRTVLTAWLGIVAVIVC
                     VSLCIPLFGKSTVLTSIPVINGALPATTIMTQAALEKGLTLAAATATVVFAIQKFIGT
                     PIASRAALQEANRLLVEYHEAKSKGIDLANVDTDKKEAENTGTKVKQAFCEKYDKYYS
                     TNVCIFFIALFSYLGYELSEIIHVNYSIVCLVVGVIVTRIGIVPKDILEKGKIKGFIN
                     MVVFAAVIPSLAKVSLTDLISLFVPIVGMFAASIIGIFLMMKVLPGWKIIGSKPLAFG
                     VGFCQMLGFPTTYLISNEVCNAVGETEEERAYLMSKIMPKLVVGGMACMISIVVAGLM
                     VPML"
     gene            complement(6601..8556)
                     /locus_tag="ACGI5H_003083"
     CDS             complement(6601..8556)
                     /locus_tag="ACGI5H_003083"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895678.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008236 - serine-type peptidase activity
                     [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="prolyl oligopeptidase family serine peptidase"
                     /protein_id="HFG9698779.1"
                     /translation="MEKIKIESSDIFEYIFPHDISCSPDGKHIAYIISNINEEKDCYE
                     HDLYVMDIKTEKQIHMTQTKDVTSFSWISNTELLFTSKRNKPKAGTTDFYTISIEGGE
                     AKKAFSIPKACSVPVSLGNKLWLLTTKNPTDSKKSEPDRAVEGVDYWTFTDKPFIRDG
                     ENFSQRRRVTLELYQEGENITKAITPKFCEVAGIDVSSDKNRILYTGQIYEDCATPFS
                     GLWEYHIDSGETKELVPQGKYQISLAKYIGKDKVMLQASTLDRSITQNHDIFILDLST
                     SEINMIASPDGMYATLLDVDAVYGGGRSNKVIGDKFIGARICRTMTEFNEFDTKTGNI
                     RIITKVDAFTSFDIYDNTMYTVMLKDYELAEIYSIDMTTGTMKKMTAFSKPYLDTHKV
                     SLPEKLTFVAKNKEEVDGFVIPPIDAKEGEKYPAVLFIHGGPKWAYGYMFTHLKQCVT
                     SKGMYVIYCNPHGGDGYGEKFLEMVERWGYVDYEHLMEFVDTCIEKYPGIDADRLGVA
                     GGSYGGYMTNWIIGHTDRFKAAVSQRGISNLITASLIIDFGDRIMKQTCGDKTPWNHE
                     EVLWNHSPIKYVKNVKTPTLFLHSDRDYRCFMGDTFQMFTALKQLGVDTEMYLFHGDT
                     HGLSRNGRPSNRIARANAIVDWFERYL"
     gene            complement(8573..10618)
                     /locus_tag="ACGI5H_003084"
     CDS             complement(8573..10618)
                     /locus_tag="ACGI5H_003084"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892720.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008236 - serine-type peptidase activity
                     [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="prolyl oligopeptidase family serine peptidase"
                     /protein_id="HFG9698780.1"
                     /translation="MKKITKERIENTMKKLFTSETFLEYQFISDCQISPDGGYTAFIV
                     KKADIKENGYTSQVYILNNKTGELKQITSINSVGAYAWEDENTILFPALRNEKVKEAV
                     KNGKQCMSYYALSLNGGEAEELFRLPIKGGKLNPIGKGLYAVIDSYDNDRPIVEGLPE
                     EEQQKKINAYNKRHYEHFKEIPYAVNGEGYISRKRKRLYVYDSNINELKAITAPMFNV
                     VGMKISDGKILYIGQEFKDVKGLKNGVYVFDTNTNTNVCILEKDKYIIKGFELYQNQV
                     ILNLTDALSYGNGENGDFYTIDIDTKEMKLLSGHQHHCIGNTVTSDVKMGAGQTTKVD
                     GEYIYYTSTVDMDCIIERIHIPTGKQEKVTQTGSVDFIDVKDGNIVCVGCLGNGLPEV
                     YTVENGTLCKKTHLNDHILEEYKISVPEYIESKGSSKWEIQGYVYKPVDYEVGKKYPA
                     VLAIHGGPRLTYGPYFMHEIQVFTSAGYFVFFCNPRGSEGRGNAFADIRKQFGEIDYI
                     DFMEFTDTVLEKYTDIDKTKLAVEGGSYGGFMTNWIIGHTNRFAVACAQRSIANWSGM
                     EGTTDIGYYFCKGQTGASHMENHELQWKQSPLAYVDKCVTPTLFLHGEKDYRCYMQEA
                     FQMFSALKIHGCPTKLCLFEGENHELSRSGRPKQKLQRLVEMLDWFSVYIKKDNIGQ"
     gene            complement(11005..11655)
                     /locus_tag="ACGI5H_003085"
     CDS             complement(11005..11655)
                     /locus_tag="ACGI5H_003085"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905011.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HFG9698781.1"
                     /translation="MKVKSNLDEILYHKIIESLIRGEYSVGQKILLNDLCEKFEVSRT
                     PVVQAVKMLNKDGVLTIMTNGKVYVPEYEYDMVKQVCETRTLIETYALEKMMQEEEEV
                     FQQKLDVIKRYSDKCEEYYRQEKSVELALADLELHKAIVEGANNEILNDVYVGIQGRF
                     IVVNYLIRPLKNRNYEGTVQDHFEILKFIEDRDTKKAVDKLRNHIQGTIKRFCEDE"
     gene            complement(12639..12812)
                     /locus_tag="ACGI5H_003086"
     CDS             complement(12639..12812)
                     /locus_tag="ACGI5H_003086"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9698782.1"
                     /translation="MLKQMLENNLPIKIVSWDSEELYRNSLNSCSLGNYVPLIEYLSS
                     LEDFREVYKMLWK"
     gene            complement(12816..12971)
                     /locus_tag="ACGI5H_003087"
                     /pseudo
     CDS             complement(12816..12971)
                     /locus_tag="ACGI5H_003087"
                     /inference="COORDINATES: protein motif:HMM:NF014691.4"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="Fic family protein"
     gene            complement(13072..13752)
                     /locus_tag="ACGI5H_003088"
     CDS             complement(13072..13752)
                     /locus_tag="ACGI5H_003088"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003440161.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease subunit"
                     /protein_id="HFG9698783.1"
                     /translation="MIHLMKLELKKVGLKRYFLFSMLGIFLCMFFVFTGLNDKSTSIY
                     DYDVTFRTISLFFCFYYIILFAVLNVAYIINEYTNKTILILFSYPLDRKKLILSKLLL
                     ITTLMISSMIVGYICCFTFVVVLDKYFNLVIGDFHISILSYWIPGAIKSIIVFCSLGI
                     WTFVVGMIRKSIPVTLVSSIIFINLRQFILAGTNTTQDSLISVFIIVGITVIGIYYIL
                     NHKVTEID"
     gene            complement(13749..14675)
                     /locus_tag="ACGI5H_003089"
     CDS             complement(13749..14675)
                     /locus_tag="ACGI5H_003089"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860893.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HFG9698784.1"
                     /translation="MNYIIETNQLKKIYKDKAVVNAVNIHVKKGEIYGFVGPNGAGKS
                     TVMKMLLNLVKPNSGEIVMFGKKVAETDFEILKKIGTIIENPYLYENLTAKQNLDLHC
                     EYMGYYNKEHISEVLECVGLSKQSNKKVSKYSLGMKQRLAIARAILTKPELLILDEPI
                     NALDPEGIREMRELFRKLNTDYGITIFISSHILSEVEQIADTIGIIQDGKLIKEISMS
                     DIHKYQTDYVEVDVDNVELAGYLLEKEFGIKDFKITSESCIEIYDLRKDVKEISKIFI
                     QNQIGINSIGRKQSSLEDYFFQTTGTGGKETL"
     gene            complement(14748..15665)
                     /locus_tag="ACGI5H_003090"
     CDS             complement(14748..15665)
                     /locus_tag="ACGI5H_003090"
                     /EC_number="2.7.13.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729264.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000155 - phosphorelay sensor kinase
                     activity [Evidence IEA];
                     GO_function: GO:0004673 - protein histidine kinase
                     activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0007165 - signal transduction [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HFG9698785.1"
                     /translation="MELFLVVISIVLFALYLKERNKSKKMESDYKYINSRLRDITNDD
                     EINYILVPSDISIVKETAVDINKLLEKFYSRQINYNRSEKAMLQIFTNISHDLRTPIT
                     VLKGYIEMLYLQSQKEELSSSMRATVEKMQTNSNELVNSINNLFNMAKIQSGDMILNL
                     QKSNLTQLCHEIILEFYDLLDKENFNVEVNIEDRPIYANVDTEALQRILKNLIDNAIK
                     YGSDGRFLGISLYEKEKHVFIDIEDKGSGISETEKEHIFTRAYTADRKKGNGLGLAIS
                     QGLVNSMGGSIYVNSRPNVKTVFTVKLKS"
     gene            complement(15665..16354)
                     /locus_tag="ACGI5H_003091"
     CDS             complement(15665..16354)
                     /locus_tag="ACGI5H_003091"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902053.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000156 - phosphorelay response regulator
                     activity [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HFG9698786.1"
                     /translation="MDILLVEDDKNIREMVYDFLISENYSVKTAIDGNTAIEIFKNYS
                     FDIILLDLMLPKSSGFEVLKYIRSVSVVPVIITTAKDSDTDKMLGLNLGADDYITKPF
                     SIVELLARIKANIRRATVYSSSRNSEDMVIQYKDLIINISKYVVSKNGIDLNLTHTEF
                     EIVKLLATNQGRAFSKEQLYNAIWKEPYYGNENVLNTHINRLRNKLSDGIEKNNYIKT
                     LWGIGYKMEEE"
     gene            complement(16762..17067)
                     /locus_tag="ACGI5H_003092"
     CDS             complement(16762..17067)
                     /locus_tag="ACGI5H_003092"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427875.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9698787.1"
                     /translation="MPSMIMEVVGVLFIAIGLILTFIEIKGNFPSFYGFGQNSIGKNA
                     VGIIAAGIALIFFRNGIDSIDSIATYGVFLAIELVVIVAYFLIRKKFTKEDKHLRTN"
BASE COUNT         6030 a         2939 c         1924 g         6777 t
ORIGIN      
        1 aacatttttc ttcactttgc attatgatat atggtttaaa taatcttctt tactttgtat
       61 tatgatacat gctttaaata tttttacgca ctttatatta taatacatgc tttaaataat
      121 cttattcgct ttgtattata acacattatt taaatatttt tactcactct gcattatagt
      181 acattattta aatatttttc ttcgctttgc attatgatac attatttaaa tatttttact
      241 caccttgtat tatggtacat tatctaaata tttttcttca ctctgtatta tgatatataa
      301 cttaaatatt ttacctcact ctacaatatt atatataatt taaatatttt tcttcacttt
      361 gtatactaaa gtttatttaa agtattttct ttcccattat actatgctgt taaatatttt
      421 tcaactgaag tattgtagaa ccttaaaatt actataaaaa actatattct aaaatacttg
      481 taatactacg tatcaccctt aacacttaag tataatttta aagcaaaatt cttattactt
      541 atatttaatt ttgattctac atctttagat ataattttaa gtaatttaag aaattattgt
      601 aaatcatata gtactactca ataattaggt ttttcaatgt tccaattatg tttctttgat
      661 ataatccacc atgactaaaa actatcgttt ctatatcata attacttata tttttaatag
      721 catcttttaa ctcttgtttg ttgctgtgca ttacatcaac aggcttaagt tctccatttt
      781 ctacctgtaa caaatctcca gcaataagta ctttagactc ttttaaataa agacatatgt
      841 gacctctagt gtgacctcct gtatgtataa cttctatttc ctcacctaga ttcaattttt
      901 catggttatc taatgacaca tctactttag tatatgatga tttaaatcca agtcccataa
      961 catttagcat actaagcatc ttatcatcaa ttttatctac catttgttcc aacatataaa
     1021 gtttaaaagg agtttcttct cctgttatat agctgatttc acttttgtat gcatatactt
     1081 tgatattatt cttagatttt tctcttagat aatttatgtt tcctatatgg tctatatcat
     1141 gatgagtaat tattatattt tttaacttat caaagctcgt gttactttta ttaagagcat
     1201 caattattaa atcaccttga cccggaagac ctgtgtcaat aagtgttgca tcatcttctg
     1261 tgtagattac aggaatatac ataactttat cttcaccgaa tacatttgat gaaattttta
     1321 aaacatctaa tccctttgct aaattcataa tttttctcct tataattact taattagagg
     1381 tcaatttaat taaagaaatt gagaaaatgt agattttcct ctagttatat tttattaatt
     1441 aaaaattatt aatacctagt atatcactta agttgaagga ttactcgact tgattttttt
     1501 gttattttat ggtatagtaa ttaatataga agtaagtaat tgcaagcttt gcaattactt
     1561 ttattttttt ctaataacta ttttattttt gataattcgt ataaaattaa aagtaaagta
     1621 atatggaaaa tatgaatata gaaaaacttt aataagaaaa taaattatga ataaataaaa
     1681 gaaacgcaat actgtatata gatgattatt tagaaaaata aaatctcttt taataaaaat
     1741 aagcttcaaa ataaactttt agttcataaa gcttaggagg aactaaattg agtgcaagtg
     1801 tatctactgt tcaaaataaa tagttcataa agcactcttt tttatattaa atcaattata
     1861 ttttcgtcat ttcagcaatg aaaaagaaac ttatctctat tttgagacag cttcttttta
     1921 ttaacttcct actttttatt agttttctaa aattgaaaag ctttatttat aggattcctt
     1981 agatttatat tttgacgata taatttttta aaaacatctt aaaagatggt atacaataca
     2041 cacaatcata ctcataattg aaaaataatc aatggaaaat aaaattactg gatattatct
     2101 attaaaaaat acaaattgat tcacaagaaa catataatct ataatattat gatgttactc
     2161 tctcgcacca agtaacttta ttttcaagta accttttaaa ttcataccat ctaacttcac
     2221 tcaataaaaa tggcaatata aatatgtact ctatttttta cttttaaata tctgacaagc
     2281 tttatatact attggaagta aaatacaaag taaaacagcc caatctggta aatgtggcat
     2341 ataaaagtcc cccttacctt atacaagctc cttattacta aaaattttaa tagaaataaa
     2401 cattgaagct aacagtataa ttaaacttaa aaggaacaat acaatattca ctatcatgga
     2461 tggatactga tatataaatg gaatttcaaa attgctgtga gctatagtta atggtaatac
     2521 aaatgatgaa gccatgatta tcaccacgaa aaagaatttt gttgtttcat atcctaattt
     2581 atattgaata ggcatataaa ctccataaat aatagaactt attaataaaa caatcaaaat
     2641 atatgttaag tcaaaagttc ctatttgtgg aataagtaaa ttttcaatcc agtaaactaa
     2701 tgtacaatag ataaatacca ttgcaaataa aacatactta gattgaacta agccacgtct
     2761 aggataagga gttgaacaaa gtaatacaga tgcttttgaa tattgactct cctttaataa
     2821 tagatactgg cacagcataa attctgaaaa tataatggat agtacaaatc ccaatatttg
     2881 tgcaaatgga ggtaaacgcc acaatgtaaa taatgggatt cctattgcaa taaacaatat
     2941 caacaataca tattttttta caatcagaat atctttttta actaaatgaa tcaacataat
     3001 tactctctcc tttcaatata tgcaagcata atatcttcaa ttgtaggacg ctctattaaa
     3061 atatctggca tatttttttg cacttcatta atttttgagg taatccctat aaaaccataa
     3121 cctgtaattt ctaaatttaa aaataatttt ttgatttcat catttagaaa ttgaatatcc
     3181 ccttttactt ttctatgttc gtccaataga gtatcttttt cacgctctaa tataatacgt
     3241 ccattgtcaa tcataacaat catatctgct attttgtcta aatcagatgt tatatgagtg
     3301 gaaaagaaaa caccacgacc acattttttc atatatcctg ttagtatgtc aagtatctga
     3361 ctacggatta gtgggtctaa accacttgta ggttcatcca taattaaaaa ctcagcttta
     3421 tgcgataatg ctaatgctaa tgcaaatttc attttcattc cttttgaaag tgtatcaatc
     3481 ttttgttttg ggttaagatt aaaacgcttc atattttgtt gataatcttc ttcacaccaa
     3541 ttatcatatg aaggtgcaat aatacttttc atttctgcca ttgacaactc ctcatagaaa
     3601 tatgaatcat caaatacaac tccaattcga ttttttaatt ccttctcatt tccatcgaaa
     3661 tctttaccaa agatttttat ttttccacta tcacgcttta cgacatccaa tatcgaacgg
     3721 attgttgttg tttttcctgc tccattaaca cctataaatc cagttataca atcttctggt
     3781 aatgcaaagc ttatattaga taatgaaaaa tcggtataag tcttatttaa gttataaact
     3841 tctaaaatat tttccatatt aatcctcctg atatagaata tccatcattt cttgtaactc
     3901 tatctgtgta attcctagtg cttttgcatc cttaatcata tctgccattt tttgttcaac
     3961 tatacgtctc tttgagtctc ttagtatttc taaatttcca gttgaaataa atgttcctat
     4021 tccaacttgg cgtgtaagaa agccttcatt ttcaagttct tcatacactc gtctaatagt
     4081 caaaatacta acttttaaat cattagcaaa atttcttatg gatggcattg catccccttc
     4141 tttcagttct tcagtaaata ttgcttcttt aatttgctct ttaatttgtt ggtataatgg
     4201 cttatctgat gtgttagaaa tgagcacttt cattttttat cacccccttt ttatcatttt
     4261 cagtgtgatg ttgttatata cacactatac acttagagca cttttttgtc aatataaaag
     4321 atgtaaaata ttactatgac aaaataaata tgaatgaaat attagagatt gttgatagct
     4381 ataaacactt tttaaaacca cataagatag aatgtattaa atatttatta aaagtaagaa
     4441 ttgaatatct aaaaaaaaga ggaatcctgt atgaatgatt tgtttgatga taaattaagt
     4501 tataaactat ttataaaaaa cataaaggaa taaatccatt tctaattaca aacatactaa
     4561 aaaatttaga tagtaataaa tagatagtaa taaatagata gtaataaatg ggatgaattt
     4621 ataagaattt ggatagagga aagagttatt caagagtgta gactagaggt aaactctata
     4681 ttaaaaaaat ttaaatttgg atattatgat gcatggaata tttgcagaag taaccttgct
     4741 ataagtatag aagatttttt tgattacaaa agataatact ctaaaatgtg aggatttcaa
     4801 cattcaatac tgtactttaa ataatatcac tgcaaaatac catccacctt ttaccataat
     4861 tgaataccct aattatttta aaaaagaaaa cattagaaac agaaaacctt ggatatataa
     4921 aataaaaaat actaacttct aaaacacgga tactctttga taaataaaac aaaaaataat
     4981 tttaataatt aaaattggct atctcaaact agagataagt ctctttctca cttttaaaac
     5041 gttgaaaata tattcgattt cgtacaaaaa agagtgcctt agaactaaaa agttcacttt
     5101 gtggcactcc cttttttctc ctctttttaa ttttttataa aaattcttca aaaatattat
     5161 taaataccct atattataca taaatcaaat taaagttgca ttttagcaaa taaaaacaaa
     5221 ttataactat tagcatagca aataaaaaat ctgctctctt ataaaatcaa attataatta
     5281 taaaaagaaa atattcttat aacaaattag ctaatataaa attattttat aaattaatac
     5341 tactttttag cttctcctat aaattaatac cactttttta actttgaaac ctatctacaa
     5401 cattggtacc ataagaccag ctaccacaat agaaatcata caagccatac caccaactac
     5461 cagcttaggc ataatcttag acatcaaata tgctctttct tcttccgttt ctccaacagc
     5521 attacacact tcatttgaaa ttaaatatgt agttgggaat cccaacatct gacaaaaccc
     5581 tactccaaaa gcaagaggtt tagaaccgat aattttccaa cctggtaaca ccttcatcat
     5641 aaggaatata ccaatgatag aagctgcaaa catacccaca attggtacaa aaagactaat
     5701 taaatctgtc aaagaaactt ttgctaaaga aggaataaca gctgcaaaca caaccatgtt
     5761 gataaatccc ttgatttttc ctttttccaa aatgtctttt ggcacaatac caatacgtgt
     5821 tacaataaca ccaacaacaa gacatacaat agaataattt acatgaataa tctctgaaag
     5881 ttcataccct agataagaga ataatgctat aaaaaatata caaacatttg tagaataata
     5941 tttatcgtat ttttcacaga aagcttgttt tacttttgtg cctgtattct ctgcttcttt
     6001 cttatcagta tcaacatttg ctaaatcaat gccttttgat tttgcttcat gatattctac
     6061 taaaagacgg tttgcctctt gtaacgctgc tcttgaagct attggtgtac caataaactt
     6121 ctgaattgca aatacaactg ttgctgtagc tgctgcaagt gtcagtcctt tttctagtgc
     6181 tgcttgtgtc ataatagtag tagcaggtaa agctccattt ataactggta tgcttgtcaa
     6241 tactgttgat tttccaaaca aaggaataca taatgagaca cagactataa ctgctacaat
     6301 tccaagccat gctgtcaata ctgttctcca ttcgtctata aattgtttaa cattcaacat
     6361 tgttcccata ctaaacataa tcattggaac actccaacta gctgctgcgg tcatacctgc
     6421 tttttcaata atatcagctg gtattgcttt tgtgacaaat agaatcaaaa ataaaagtag
     6481 tgtaacaaat acagctgata cttttgcttt tgttttgctt gcaattaaat ccccaatagc
     6541 aaataaaact aatacgacac taaaccataa taacatatca ctcatagaat aaccccctta
     6601 ttataaatat ctttcaaacc aatctacaat agcatttgct cttgcaattc tattagatgg
     6661 tcttccattt ctagacaatc catgtgtatc tccgtggaac aaatacattt ctgtatctac
     6721 accaagctgt tttaatgctg taaacatttg gaaagtatcc cccataaaac atctataatc
     6781 cctatcacta tgtaagaaca atgttggtgt cttaacattt ttcacatatt taataggtga
     6841 atgattccaa agaacctcct catgattcca aggcgtctta tctccacaag tctgcttcat
     6901 aattctatcc ccaaagtcaa taattaaaga agctgtaatc aagttactaa tacctctttg
     6961 agaaactgct gctttgaaac ggtctgtatg accaattatc cagtttgtca tataaccacc
     7021 gtaacttccc cctgcaaccc ctaagcggtc tgcatcaatc ccaggatatt tttcaataca
     7081 agtatctaca aattccataa gatgctcata gtcaacatac ccccatcttt ctaccatttc
     7141 taagaatttt tcaccataac cgtcaccacc atgagggtta caataaatca catacattcc
     7201 ctttgatgtt acacactgct tcaagtgtgt aaacatatag ccatatgccc atttaggccc
     7261 accatgaatg aacaatacag caggatattt ttcgccttct ttagcatcta taggtggtat
     7321 aacaaaacca tcaacttctt ctttattttt tgctacaaac gtcaattttt caggtaatga
     7381 aaccttatga gtatctaaat atggtttaga aaaagcagtc atttttttca ttgtacctgt
     7441 agtcatatca atgctatata tttctgctaa ctcataatct ttcaacatta ctgtgtacat
     7501 ggtgttgtcg taaatatcaa aagatgtaaa agcatctact tttgtgatga tacgtatatt
     7561 acctgtcttt gtatcaaact cattaaattc tgtcatagtt ctgcaaattc ttgcaccaat
     7621 aaatttatct cctataactt tattactacg tccaccacca tatactgcat ctacatccag
     7681 taatgtagca tacataccat ctggactagc aatcatattt atttcactag tactcaaatc
     7741 aagtataaaa atatcatgat tctgtgtaat agaacggtct aatgttgaag cttgcaacat
     7801 tactttatct ttgccaatat attttgccaa acttatttgg tactttcctt gtggtacaag
     7861 ttctttggtt tcaccactgt ctatatgata ctcccaaagt ccagaaaaag gagttgcaca
     7921 atcttcataa atctgaccag tatataaaat tctgttttta tccgaagaaa catctatacc
     7981 tgctacttca caaaattttg gtgtaatggc ttttgttata ttttcacctt cttgatataa
     8041 ttctaatgtt acacgtcttc tttgagaaaa attttctcca tctcttataa aaggtttatc
     8101 tgtaaatgtc caataatcta caccctctac tgccctatct ggttctgatt ttttagaatc
     8161 cgttggattt tttgttgtca gtaaccacaa tttatttcca agtgatacag gtacgctaca
     8221 agcttttgga atagaaaatg ctttttttgc ttctcctcct tctatagaaa tagtgtaaaa
     8281 atctgttgta cctgcttttg gcttatttct tttagatgta aaaagtagtt ctgtattaga
     8341 aatccaacta aatgatgtta catcttttgt ttgagtcata tgtatttgtt tttctgtttt
     8401 gatgtccatc acatataagt catgttcata gcagtctttt tcctcgttga tatttgatat
     8461 aatataagca atatgctttc catcaggtga acaagaaata tcatgaggga atatatattc
     8521 aaaaatatct gaactttcaa tctttatttt ttccattttt atattctcct ttctactgtc
     8581 ctatgttatc tttttttata tataccgaaa accaatctag catttcaact aatctttgta
     8641 gcttttgttt tggtctacca gaacgagaca gttcatggtt ttctccttca aatagacaaa
     8701 gttttgtagg acacccatga attttcaatg ctgaaaacat ctggaatgct tcttgcatat
     8761 agcatctata gtctttttca ccatgtaaaa ataaagtcgg tgtaacacat ttatcaacat
     8821 aagcaagagg tgactgtttc cattgaagct cgtggttttc catatgagaa gcacctgttt
     8881 gtcctttgca gaaataataa ccaatgtctg ttgtaccctc catgccactc cagtttgcaa
     8941 tagaacgctg agcacaagca acagcaaaac ggtttgtatg accaattatc caattcgtca
     9001 taaatccacc ataacttcca ccttcaacag ccaattttgt tttatcaatg tctgtatatt
     9061 tttcaagtac agtatctgta aattccataa aatctatata atcaatttct ccaaactgtt
     9121 tcctaatatc tgcaaaagca ttgccacgac cttcagaccc ccttgggtta cagaagaata
     9181 caaagtaacc tgcacttgta aatacctgta tctcatgcat aaaatatggt ccatatgtca
     9241 atcttggtcc tccatgaatc gccaatacag ctggatattt tttccccacc tcataatcta
     9301 ctggtttata tacgtatcct tgtatttccc atttagaact tccttttgac tctatgtatt
     9361 ctggcacaga aattttatat tcctctaaaa tatggtcatt taaatgtgtt ttcttacaca
     9421 atgttccatt ctctactgta taaacttctg gtaatccatt tcctaaacaa cccacacata
     9481 caatattgcc atcttttaca tctataaaat caactgaacc tgtctgtgtt actttttcct
     9541 gttttcctgt tggaatatgt attctttcaa taatgcagtc catatctact gtagaagtgt
     9601 aataaatata ttctccatct acctttgttg tctgaccagc acccatttta acatcagatg
     9661 ttactgtatt tccaatacaa tgatgttgat gccctgaaag aagtttcatt tctttcgtat
     9721 caatatcaat agtataaaaa tctccatttt ctccatttcc ataagataaa gcatcagtta
     9781 ggtttagtat cacttgattt tgatataatt caaaaccttt tataatatac ttatcttttt
     9841 ctaatataca gacatttgtg tttgtgtttg tatcaaatac atagacccca tttttcaaac
     9901 cttttacatc tttaaattct tgccctatat ataagatttt tccatcactt attttcatac
     9961 ctacaacatt aaacataggt gctgtaattg ccttcaactc atttatatta ctatcgtata
    10021 catataggcg ttttcttttt ctgctaatat atccctcccc attgacagca taaggaattt
    10081 ctttgaaatg ttcataatgt cttttgttat aagcatttat ttttttctgt tgttcttctt
    10141 ctggcaatcc ctctacaata ggtcggtcat tgtcataaga atcaataact gcatacaaac
    10201 cttttcctat aggattcaat ttaccacctt tgatagggag tctaaaaagt tcttctgctt
    10261 ctccaccatt taaagataaa gcatagtaac tcatgcattg cttaccgttt ttgacagctt
    10321 cttttacttt ttcatttcgc aaagcaggga acaagatagt attttcatct tcccaggcat
    10381 atgctccaac agagtttata gacgttattt gttttaattc gccagtttta ttgtttaata
    10441 tataaacttg gcttgtgtaa ccattctctt tgatatcagc tttttttaca ataaatgctg
    10501 tatatcctcc atctggtgat atttggcaat cacttataaa ttgatattcc aaaaatgttt
    10561 cactcgtaaa tagctttttc atagtatttt ctatcctttc tttagtaatt tttttcaaac
    10621 tccctaccac ctctttcatt ttttatttta aatttaaaat aaaaaatttt aaatttaaaa
    10681 taaaaaattt tataaaggtt atttttttag gaagccttct ggcttccttg taatatttgt
    10741 aatttaaagt atatttaatc catgcttaat tcatgcttaa ttcatactta atctatactt
    10801 aatctatact tagtccatac ttaatctata tttaattcat acttagactt atttacacta
    10861 tatttagatt atatttatta gattatattt attagattat atttattaga ttatatttag
    10921 attatgttta aactataatt agattatact tagactacat ttagcaactt aatagataag
    10981 tatatatagt aacttcaaaa cttattattc atcttcacag aatcttttaa tagttccttg
    11041 aatatgattt cttagtttat ctactgcttt ttttgtatct ctgtcttcaa tgaattttaa
    11101 tatttcaaaa tggtcttgta ctgttccttc ataattacga ttttttaatg gtcgaattaa
    11161 atagttcact actataaatc ttccttgtat accaacatat acatcattta aaatctcatt
    11221 atttgcccct tctacaatgg ctttatgtaa ttccaaatct gctagtgcaa gttctacaga
    11281 tttttcttga cgatagtact cctcgcattt atcagagtat ctttttatta catctagctt
    11341 ttgttgaaaa acctcttcct cttcttgcat cattttttct aaagcatatg tttcaatcag
    11401 tgttctcgtt tcacaaactt gttttaccat atcatattca tactctggta cgtacacttt
    11461 accatttgtc ataatagtaa gcactccatc tttatttagc atttttactg cttgtacaac
    11521 tggtgttctg cttacttcaa atttttcaca aaggtcattt agtaatattt tttgacctac
    11581 agagtattca ccacgaataa gactttcaat aatcttatga tataaaattt catctaaatt
    11641 tgactttact ttcactactc tcaccttatt tctattcttt tgccatatta tattgaatta
    11701 ctggacttta attactttta gtaatatttt taaagtagaa attcttattt gatagtactt
    11761 ttgtactaca atttaaatta ttgtactgta aatcatgctc ttatactata gattaattca
    11821 ttgtattgca aatcaagtta ttgtactata gattaaatcg ttatacttca aattaaacta
    11881 ttatactata gattaaacca ttgtacttca aattaaacta ttatactata gattaaatcg
    11941 ttgtacttca aattaaacta ttatactata gattaattca ttgtacttca aattaaacta
    12001 ttataccata gattaattca ttgtattgca aatcaagtta ttgtactata gattaaatcg
    12061 ttgtacttca aatcaagtta ttgtactata gattaaatcg ttgtacttta aattaaacta
    12121 ttatactata gattaattca ttgttctgca aatcatgcta gtgtactaca aattaaacta
    12181 taaatgttta ctatctctta ataatttgaa taatatgtta caaaaagtat agcacctttt
    12241 tatttttttc gcaataaata aaaaatttaa aattttttat tttttatttt cttatattat
    12301 caatttgaaa tatgaaagat taagactaat agaattgatt cagttaattg aaaaaaatag
    12361 gtacctttta tgaaaattct aatgataagc atttttctga tgtaatggta aattataaat
    12421 gataaaatta aaaatcactt ttagttttat gaactgtccc catattaaga aacaactaag
    12481 atacataaaa atagttataa agagatagtt aaactatatc cactatttta tatagttaaa
    12541 atagtgggta tagtccaagc taagaataac taagaaatta gcgttaaata gcatagataa
    12601 aaatacattt atatataaac tttttttgct gcaaacaatt atttccataa cattttatat
    12661 acttctctaa aatcttctaa acttgataaa tattcaatta aagggacata attacctaaa
    12721 ctacaagaat ttaaggagtt tctatacaat tcctcactat cccaagatac aatttttata
    12781 ggaagattat tttctaacat ctgttttagc ataacaaatc tacctatgtg accattacca
    12841 tcttgaaatg gatgtatcaa ttcaaatcta taatgaaatt cagttataac tttaatagat
    12901 acttcactct gactatagta ccattcaatt aattcatcaa gctttggctc aacttcaaat
    12961 ggttgtgcaa tattattaaa actctaataa tattaataat agctgatata atagcaaatc
    13021 attattatcc cgagaagata caattaataa ctaccttcct atccacagta tctagtcaat
    13081 ttcagtaact ttatgattta gtatataata tataccaatc acagttatac caactataat
    13141 aaaaacagaa atcaaactgt cttgagttgt atttgtacca gctaaaataa attgtcttaa
    13201 attgataaaa ataattgaac tgacaagggt aacaggtatt gattttctta tcattccaac
    13261 aacgaatgtc catataccta atgagcaaaa tacaataata cttttaattg ctcctggtat
    13321 ccaataagat aaaattgaaa tatgaaaatc tccaataact aaattaaaat acttatccaa
    13381 cacaacaacg aatgtaaaac aacagatata tccaactatc attgatgata tcataagagt
    13441 cgtaatcaaa agtaactttg ataaaataag ttttttacgg tcaagtggat aagagaataa
    13501 aatcaagatt gttttatttg tatattcatt tattatatat gccacattca acacagcaaa
    13561 taatataata tagtaaaaac agaaaaataa actgattgtc ctaaatgtaa catcataatc
    13621 atatattgaa gtagatttat cattcaatcc agtaaagaca aaaaacatac ataagaaaat
    13681 ccccagcatt gaaaataaaa aatatctttt tagcccaact ttttttagct ctagtttcat
    13741 taaatgtatc atagtgtttc tttacctcct gtacctgtag tttggaagaa gtaatcttct
    13801 aaagaacttt gtttacgtcc aatgctattt ataccaattt gattttgaat aaatattttg
    13861 gatatttctt ttacatcttt tcgtaaatca tatatttcaa tacaactttc cgaagtaatt
    13921 ttaaagtctt ttattccaaa ttctttttct aacaagtatc cagcaagctc cacattatct
    13981 acatctactt caacataatc tgtttgatat ttgtgtatat ctgacataga aatttcttta
    14041 ataagtttac catcttgaat aattccaata gtgtccgcaa tttgttctac ctctgaaaga
    14101 atatgactag aaataaatat agttattcca taatctgtat ttaacttacg gaataattct
    14161 cgcatttctc ttatcccctc tgggtcgagt gcatttatag gttcatcaag aatcaataat
    14221 tctggtttag taagaattgc tctagctatt gcaagacgtt gtttcatccc taaagaatat
    14281 tttgaaactt tcttgtttga ttgctttgac aatccgacac attccaatac ctctgatata
    14341 tgttctttgt tataataacc catatattca cagtgtaaat caagattctg tttagcagtc
    14401 aaattctcat ataaatacgg attttcaata atagtaccaa tcttttttaa tatttcaaaa
    14461 tcagtttctg ccactttctt accgaacata actatttctc cagaatttgg cttaacaaga
    14521 tttagcaaca ttttcattac tgtactttta cctgccccgt ttggtccaac aaatccataa
    14581 atttctccct ttttcacatg aatattaaca gcattaacaa cagctttatc tttatatatt
    14641 ttctttaatt gattggtctc tatgatatag ttcatcatac tccctccttt ctaaaaacag
    14701 tatacaaaat aaaattatct tttctctctt ttaaatctaa cttttttcta acttttcaat
    14761 tttactgtaa aaactgtttt tacattaggt ctactattta cataaattga acctcccata
    14821 gagtttacaa gcccttgaga aatagccaaa cctaaaccat tgcctttttt tctgtcagca
    14881 gtataagctc ttgtgaaaat atgctctttt tcagtttcag aaatacctga acctttatcc
    14941 tcaatatcta taaaaacatg tttttccttt tcatatagtg aaatccctaa aaatctacca
    15001 tctgaaccat attttatagc attatcaatt aaatttttga gtatacgttg taatgcttct
    15061 gtgtcaacat ttgcatatat aggtctatct tcaatattaa cttcaacatt aaagttttct
    15121 ttatctagca aatcataaaa ctctaaaata atctcatgac ataattgtgt tagattggat
    15181 ttttgaagat ttaatatcat atctccagat tggatttttg ccatattaaa caggttattt
    15241 attgaattaa caagctcatt tgaatttgtt tgcatttttt ccacagttgc tctcattgaa
    15301 gaagataatt cttctttttg actttgaaga tataacattt caatataacc ctttaatact
    15361 gtgatgggag ttcgtaaatc gtgtgatatg tttgtaaata tttgcaacat cgctttttca
    15421 cttctattat aattaatttg cctgctgtaa aacttttcaa gaagtttatt tatatctact
    15481 gctgtttctt ttacaatcga aatatcagat ggtactaaaa tataattaat ttcatcatca
    15541 tttgttatgt cacgaagtct tgaattgata tacttataat cactttccat tttctttgat
    15601 ttatttcgtt cttttaagta gagagcaaat agtacaatcg aaattacaac taaaaataac
    15661 tccattattc ttcctccatt ttgtagccaa ttccccaaag agttttaata taattatttt
    15721 tttctatacc atcagacaat ttatttctta acctgttaat atgagtattt agcacatttt
    15781 catttccata ataaggttct ttccaaatag cgttgtataa ttgttccttt gaaaaagcac
    15841 gtccttgatt agtcgctagt aatttaacaa tttcaaattc tgtatgtgtt aagtttaagt
    15901 caattccatt ctttgaaact acatattttg atatatttat aatcaaatct ttatactgaa
    15961 taaccatatc ttcagagttt cttgaactgc tgtacactgt tgcacgtcta atattagctt
    16021 taattcttgc aagcaattct acgattgaaa aaggctttgt aatataatca tctgcaccaa
    16081 gattaagccc tagcatttta tctgtgtcac tatctttcgc agtagtaata ataacaggaa
    16141 caacactcac acttcgtata tattttaata cttcaaaacc actagacttt ggtaacatca
    16201 agtccagtaa aataatatca aatgaataat ttttaaatat ttcaatagct gtatttccat
    16261 caatggcagt tttaacagag taattctcac taatcagaaa atcgtatacc atttctcgaa
    16321 tattcttatc atcttcaacc aataagatgt ccattattat tcaactcctt ttcgtcagta
    16381 tacttcaaat gatatattta ttaaaaaggg ttgtcaataa ataactgctt atgatattgt
    16441 atctgcaatt tggtgatact cttctaagtt aaagttcttt tcaataagct ttattgaaaa
    16501 aataattaaa atatagtata ctctcttatc tttatctgaa atatacataa ttttctttta
    16561 ttaacatcta caattaacta ttttatatta taaaacacct tttaactctt gctaaaaaat
    16621 attttataca taaaaaagaa accacattct agttttatac agaacatagt ttctttaaaa
    16681 ataatcaaat ttggatttta aataattaaa aacaaacttt tatttgtttt taattttcca
    16741 attttatagt agataattta gttaattagt tcttaaatgt ttatcttctt tagtaaattt
    16801 ttttcttatt aagaaatatg caactattac aacaagttct attgctaaaa atacaccata
    16861 agtagctata gaatctatgc tatctatgcc atttctaaag aaaattaaag caattcctgc
    16921 tgctataata cctacagcat ttttccctat agaattttga ccaaaaccat aaaaagaagg
    16981 gaaatttcct tttatttcaa tgaatgtcaa gattaatcca atagctataa atagtactcc
    17041 tacaacttcc ataatcatgc taggcatttt gacccctcct tattaataat taactactac
    17101 tataaaaata tttattattt ttataattat attatatatg cgattacatg tttttggaag
    17161 tatatttgga agtaatttca tatttattta acttaatttt tttgtgataa aatacttcta
    17221 atttttatat agatattatt ataaattttc tagtttatgg agtcattcat tctataattc
    17281 acaaatatgt attttttaat ctattaaagt attcattttc tggcttataa gcatggactt
    17341 cttatctata agcttggttt ttcatctaat aagttattta ttctttaatc tatgagcttg
    17401 atttttcatc tataagtcat ttatttttta atctatgagt ttggtttttc atctataaat
    17461 aagtcatttt ttaatctata agtttagttc ttcatctata aatcatttat tttttaatct
    17521 ataagtttgg tttttcatct ataaataagt catttatttt ttaatctata agtttagttc
    17581 ttcatctata aatcatttat tttttaatct atgagcttga tttttatcta taattaattc
    17641 attctctaat ctattagctt ggtttttatt
//
LOCUS       DAYAOO010000086        17445 bp    DNA     linear   BCT 12-OCT-2024
DEFINITION  TPA_asm: Clostridioides difficile isolate ST8-SSI-h139-18
            SAMN40601845-rid21577343.denovo.086, whole genome shotgun sequence.
ACCESSION   DAYAOO010000086 DAYAOO010000000
VERSION     DAYAOO010000086.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN40601845
            Sequence Read Archive: SRR28438827
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 17445)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 17445)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-MAY-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-MAY-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002157583.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002157583.1
            Genome Coverage       :: 163x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/11/2024 16:19:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 4,038
            CDSs (total)                      :: 3,963
            Genes (coding)                    :: 3,930
            CDSs (with protein)               :: 3,930
            Genes (RNA)                       :: 75
            rRNAs                             :: 6, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 60
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 33
            CDSs (without protein)            :: 33
            Pseudo Genes (ambiguous residues) :: 0 of 33
            Pseudo Genes (frameshifted)       :: 7 of 33
            Pseudo Genes (incomplete)         :: 25 of 33
            Pseudo Genes (internal stop)      :: 11 of 33
            Pseudo Genes (multiple problems)  :: 8 of 33
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..17445
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN40601845-rid21577343.denovo.086"
                     /isolate="ST8-SSI-h139-18"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Denmark"
                     /collection_date="2018"
                     /collected_by="Statens Serum Institute"
     misc_binding    <1..228
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            336..1817
                     /gene="thrC"
                     /locus_tag="ACGI5H_003093"
     CDS             336..1817
                     /gene="thrC"
                     /locus_tag="ACGI5H_003093"
                     /EC_number="4.2.3.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897260.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004795 - threonine synthase activity
                     [Evidence IEA];
                     GO_process: GO:0009088 - threonine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="threonine synthase"
                     /protein_id="HFG9698788.1"
                     /translation="MYYSSTRGTEEKVTASQAIIKGISNDGGLYVPSEFPNVKNELIN
                     LVNLTYSQIAFFVLSKFLCDFTEDEIKNCIENAYDEKFDCSSIAPLNKVNDTYFLELY
                     HGPTLAFKDMALTIMPHLLKTSIKKDNLEKDVVILTATSGDTGKAALEGFKDIDKIKI
                     IVFFPEDGVSPVQKLQMKTQTGKNTYVVGIKGNFDDAQSGVKKIFSDKEFNQKLLDNN
                     YILSSANSINIGRLLPQVAYYFYSYMKLVSNSDINLNDKINFVVPTGNFGNILAGYYA
                     KQMGLPINKLICASNDNNVLYDFFKTGVYDKNRTLKLTTSPSMDILISSNLERLLFEI
                     SNRNTDIVNKLLSDLSDKGVYKISDDMEKNLASFYGEYSNEEEVKSTINNVFKNYNYL
                     IDTHTAVAYNCYEKYKKETSDNTKTVIVSTASPFKFSEDVLKSIDCDFKDLDDFAIID
                     RLSSISKIDIPKPIKNLKNAEILHKDIYEKDELKLAIKKFLKV"
     gene            1827..2720
                     /gene="thrB"
                     /locus_tag="ACGI5H_003094"
     CDS             1827..2720
                     /gene="thrB"
                     /locus_tag="ACGI5H_003094"
                     /EC_number="2.7.1.39"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897262.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004413 - homoserine kinase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0009088 - threonine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="homoserine kinase"
                     /protein_id="HFG9698789.1"
                     /translation="MLEIIVPATSANIGPGFDCLGIALNIYNKFYVEEIESGLEIEGC
                     EDAYKNENNLVYTSMKYFFDRVKPEKIPAGIKIKIQSEVPICRGLGSSASCIVAGVIA
                     ANALSGANLDKNQLLNIASEIEGHPDNVAPAILGNMIVSVTDNENIHYDIIKIPEELK
                     FCAMIPNFKLSTEKARGVLPKEIPYSDGVFNVSRVALLISALLNKNFDLLKVACQDKL
                     HQDYRGTLIENYNDIVEKSEQLNSIGVFLSGAGPTIMSLIKENDDSFVDNMKNYLQKL
                     KSDWEIKELCCDSNGAVLNII"
     gene            2850..3905
                     /locus_tag="ACGI5H_003095"
     CDS             2850..3905
                     /locus_tag="ACGI5H_003095"
                     /EC_number="1.13.12.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018592431.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004497 - monooxygenase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent flavin oxidoreductase"
                     /protein_id="HFG9698790.1"
                     /translation="MKELIIRDLVAKVPIIQGGMGVGISRSSLAGAVAKLGGVGVISG
                     VQIGYDEEDFETNTINANLRAIKKHISKAKEISNGGIIGINFMVAMKEYETYVKEAVK
                     AGVDLIISGAGLPNKLPSLVKGSNVKIAPIVSTAKAANVILKMWDRKEKTTADLIVVE
                     GPKAGGHLGYSNEELDNIDSIDYDKEFVEILKVANTYGEKFGRNIPVVAAGGITSSSD
                     VKKYIDMGASGVQVGTRFVATYECDAHENFKMAYINASEEDVHIVKSPVGLPGRAIRN
                     KFIEEVKINRPEIKKCYNCLIPCNPKETPYCISQALINAVKGDVENSLLFCGNDAYKI
                     DKLSTVEDVINELISEL"
     gene            complement(4060..4572)
                     /locus_tag="ACGI5H_003096"
     CDS             complement(4060..4572)
                     /locus_tag="ACGI5H_003096"
                     /EC_number="1.5.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0010181 - FMN binding [Evidence IEA];
                     GO_function: GO:0016646 - oxidoreductase activity, acting
                     on the CH-NH group of donors, NAD or NADP as acceptor
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="flavin reductase family protein"
                     /protein_id="HFG9698791.1"
                     /translation="MSDFKEILAEEIKNNPFGLIGKDWTLITAENEGKVNTMTASWGG
                     LGVMWGKDVAFVVIRPQRYTKEFIDNTDKFSLTFFDEDFRKELSYCGKVSGREEDKIS
                     QIGFNIEHLNDTPYFKESKMAIICKKMYSQKLEPQCFIAEGIDGRWYPQKDYHTLYIA
                     EITNVLVKED"
     gene            5092..6027
                     /locus_tag="ACGI5H_003097"
     CDS             5092..6027
                     /locus_tag="ACGI5H_003097"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424475.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0046873 - metal ion transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0030001 - metal ion transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="magnesium transporter CorA family protein"
                     /protein_id="HFG9698792.1"
                     /translation="MIRYYKTIDSKLEKLSFFEDGCWINLVEPNHSEINEISNLLNID
                     VESIESALDEEERSRIDVEDNHTLILIDIPVDESDSNSSHYTTIPLGIILTEEAIVTV
                     CDAQTKILNDFIVGHIKDFFTFKKTRFLLQILHKNAAYYLHYLRKINKMTIIIEREIY
                     KSMKNKELVQLLELEKSLVYFSTSLKSNELVLNKMVRTAGIKKYPDDEDLLEDVIVEN
                     RQALDMAKIYGDILSRIMDAFSAIISNNQNNVMQILTVVTLIFSIPTIISGFFGMNVI
                     NMPFSNNPNGFWIILLITSIICIVITFFMSRNKLL"
     gene            complement(6119..7990)
                     /locus_tag="ACGI5H_003098"
     CDS             complement(6119..7990)
                     /locus_tag="ACGI5H_003098"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434025.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetratricopeptide repeat protein"
                     /protein_id="HFG9698793.1"
                     /translation="MKNTKFSIKKIKNISNDPKVVHTKGALLEKMGKMESAIELYKSA
                     ALDNYVKSQYTLGNIYESKKQFKEAEKWYSMAYKSGSEDAAFDLGNMYYKLDGYEYAI
                     YWYEKIANLGYLQAQNNLGVCHFKMKDFVRCEKWLKTAADKNLGKACFNLGVLYTFLE
                     KDDEAYEYYKKGSVLLDDDAKYNLAILNGKKKDNKSTVSLYKQLYKSGHMKGCFNLGM
                     IMEINDNLEDAEKYYKKSADRDDVKSEYRLAYVYDRKEELGDAIYYYEKAIEKNHTLS
                     KYRLANLYNRENEIEKAKTYYKMAAEDDITEAKNNLAGIYFEEKDYENAIKYYEDAIA
                     VGCKSSLENLGDLYYQNQDIEKAISYYSRIPNNVSCQIKLGNIYEDLNNIEEAISWYK
                     KASENGDTRSSYRLGCIYESLGNTKNARKYFEMASSKNHMNARIHLGRIYFREGKLEE
                     SKMMFDTPANENNVYAQHMVGLIYDMFYKDYVNSKFWYEKARAQGCVESIYNLGQIYL
                     KLNDDAEAEKYYKEGIKYGSKKCEYMLAGLYYKKSLDMYISLANEEYDNCEEIVEGFP
                     NLNIDFDEVLIPPFKLQEEVIDEEEYVPIYILNIKESLDSMLEGLETEMIIDEEHDS"
     gene            8180..9106
                     /locus_tag="ACGI5H_003099"
     CDS             8180..9106
                     /locus_tag="ACGI5H_003099"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424480.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="AEC family transporter"
                     /protein_id="HFG9698794.1"
                     /translation="MNFSNIFIQVAVLFIIILVGYFVRKFNLLDDHCTSKLSTLTMTV
                     FLPSMIISSMQINFDSKMIQKILLLLFTSLIMYIVSIIIAFLLKYILKCNDKKDLGIY
                     QYIVVFSNVAFMGYPVIEAVLGHEAIFYTAIFNLPFNLFSFTLGIYLLSKGSTSRGFS
                     IKSLISPATIAIVIGLFLFVTGLRLPQFINEPLEMLGSITTPISMIIIGSLLANSSAL
                     DCFVNKKLYIVTFIRLLVLPVIVYFILKGWINDKMILAIPVVISSMPAAANTAIMANQ
                     YDSNITLASQCVFFTTLFSVISIPFISILLLS"
     gene            9245..9391
                     /locus_tag="ACGI5H_003100"
     CDS             9245..9391
                     /locus_tag="ACGI5H_003100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890260.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9698795.1"
                     /translation="MDMDLLFKIVFAIVAIGVSVKIIKTVASLAFKIALILLIILFVY
                     RMFL"
     gene            complement(9496..10020)
                     /locus_tag="ACGI5H_003101"
     CDS             complement(9496..10020)
                     /locus_tag="ACGI5H_003101"
                     /EC_number="2.3.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:0016746 - acyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HFG9698796.1"
                     /translation="MSKPIDITIRPIRREDAQAFNEIRRTYSVMRNTLALMSDRVDKT
                     EAMLASLGENDYMFVAETNNNGEKDVIGFAGLHVNSSPRLRHSAEIGISVAENYQGRG
                     VGKKLMEQLLDIADNWIMLTRVGLEVIVDNEKGLNLYKKLGFEIEGTKKYAVIRDGKF
                     EDVYIMGRYNKNLI"
     gene            complement(10073..10297)
                     /locus_tag="ACGI5H_003102"
     CDS             complement(10073..10297)
                     /locus_tag="ACGI5H_003102"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434018.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9698797.1"
                     /translation="MIIKLTKDNFNFRFKQYEGMFFHAEVVEGMESIRYKITKDKEGT
                     ELKEFGSTHIKDNMIYVPQVEAYIDLNSIK"
     gene            10494..11618
                     /locus_tag="ACGI5H_003103"
     CDS             10494..11618
                     /locus_tag="ACGI5H_003103"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861460.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3810 domain-containing protein"
                     /protein_id="HFG9698798.1"
                     /translation="MSKKTKYFSLILFPIALLLNFIASKVPNIVEKYYSQFIDKIIVQ
                     ILSKVSGIFPFSLYEITMYIIVISTFLFLCCTLSTIFNKKKKLNIYLKNSILNILSIV
                     SIVYFLFVVLWGINYNRIPLETTLINNYNLKNNTSIQSKQYSVKELTKLYKFLVIKAN
                     ETRKLTLQDKNGIVKSNTDYNGVINRAQLGYDNILDILPGVSDSYSKPKYIISSNLMC
                     YTGITGIYFPFTGEANVNIAIPDLYIPCTVEHEMAHQRGFASEDEANFIAYLTSIKHP
                     NIDFNYSGYILALNYTASALSKVDYNAYVDISAGISDSVRRDLKNESEFWQKYEGKIN
                     EISNEFNNSYLKANGVTEGTQSYGKMVDLLLTYYELYPYN"
     gene            complement(12092..12916)
                     /locus_tag="ACGI5H_003104"
     CDS             complement(12092..12916)
                     /locus_tag="ACGI5H_003104"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893472.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF5780 domain-containing protein"
                     /protein_id="HFG9698799.1"
                     /translation="MRYKKISSLPILVVALLITGTTTTFSLSTTNSEKTNVYLANTVS
                     TVTKKVSDIQSSKGLVYNENIPLFINNSKIQYDDTPYHWPSNVISLTNSSEKAIMDYE
                     ITCLAYDKNGKPLELYWDAQNVAADGEVGSVGFSPAGVDYGIVTGISPVSPKSYSHTY
                     RKMQQSPPQDIISMFEKQQGKAWVENWLKEWKQMEKEYAKQNAIAPGKNQNDAFLLFD
                     KWKQSTGEHGVKYIISCVKQVTFNDGSVWKNSAYENWLKSFQGKEVSNSVLENYYK"
     gene            complement(13264..14319)
                     /gene="ispG"
                     /locus_tag="ACGI5H_003105"
                     /gene_synonym="gcpE"
     CDS             complement(13264..14319)
                     /gene="ispG"
                     /locus_tag="ACGI5H_003105"
                     /gene_synonym="gcpE"
                     /EC_number="1.17.7.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424490.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0046429 - 4-hydroxy-3-methylbut-2-en-1-yl
                     diphosphate synthase activity (ferredoxin) [Evidence IEA];
                     GO_process: GO:0044237 - cellular metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="flavodoxin-dependent
                     (E)-4-hydroxy-3-methylbut-2-enyl-diphosphate synthase"
                     /protein_id="HFG9698800.1"
                     /translation="MSYERRKTREVSVGAVKIGGENPISIQSMTNTDTRDADATIAQI
                     KRLEEAGCDIVRVAVPDIKAAKNIAKIKSSVNIPIIADIHFDYKLALEAIEQGVDGIR
                     INPGNIGSIERVKMVVEKCKERNLKIRIGVNGGSLEKELLKKYGSATAEALVESAMGH
                     IKILEDLDFHNIVISLKSSDIYKTVDAYELISKKVDYPLHIGITESGSVHKGTIKSSI
                     GVGALLLKGIGDTVRISLTGDPVEEVIVGKQILRSLGLLNDKIKVISCPTCGRCNIDL
                     ISVVNEVEEKIGSMEKNITVAIMGCAVNGPGEAREADIGIAGGKGEGLLFKKGEIVRM
                     IDGNKLVDELLEEIEKL"
     gene            complement(14502..15506)
                     /gene="rseP"
                     /locus_tag="ACGI5H_003106"
     CDS             complement(14502..15506)
                     /gene="rseP"
                     /locus_tag="ACGI5H_003106"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0004222 - metalloendopeptidase activity
                     [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="RIP metalloprotease RseP"
                     /protein_id="HFG9698801.1"
                     /translation="MTIIAALILFSIIVLIHELGHFIFAKRSGIKVNEFSIGMGPKIY
                     SVKKDTEYSIRALPIGGYVSMEGEDEEQISPNSFGNKSILQRFSTIVAGPIFNIILAA
                     ILLVPVFLYIGSPTTKLGKIMPDTPAQAVGLQVGDKINKINGNSVKTWDEVANIINTS
                     SGGELKLSITRDGSDKVVNVTPKNNNGKYEIGIQPQREKDFLGSIVNACKTTVDMTKQ
                     MLTFLGQMITGRVPGGIGNAVAGPVGVIGMVSDAARTGIINVVYLAAVISLNLGIVNL
                     LPIPALDGWRILMLLLEAVRGGKKLDPNKEGMINVVGFGALMLFMLFITYKDILRLFQ
                     "
     gene            complement(15519..16673)
                     /locus_tag="ACGI5H_003107"
     CDS             complement(15519..16673)
                     /locus_tag="ACGI5H_003107"
                     /EC_number="1.1.1.267"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430604.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005515 - protein binding [Evidence IEA];
                     GO_function: GO:0030604 - 1-deoxy-D-xylulose-5-phosphate
                     reductoisomerase activity [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_function: GO:0070402 - NADPH binding [Evidence IEA];
                     GO_process: GO:0008299 - isoprenoid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="1-deoxy-D-xylulose-5-phosphate reductoisomerase"
                     /protein_id="HFG9698802.1"
                     /translation="MKKISILGSTGSIGKQTLDVVREHRDKFEIVAISANSNIELLLE
                     QIVEFKPKYVTVFEENKALKLKEMLPKNIEIEVLAGMEGLKIISSLDEVDVLLTAVVG
                     MIGLVPTLCAIKKGIDIALANKETLVTAGELVMKEAEKYNVNILPVDSEHSAIFQCLN
                     GENKKNIEKIILTASGGPFRGKKKGELANITKNEALKHPNWSMGRKISIDSSTLMNKG
                     LEVIEARWLFGVEQENIDVVVHPQSIIHSMVQYTDSSIIAQLGCPDMRLPIQYALTYP
                     DRMESSFERMNFSKFSTLTFEEPDLETFPCLKLAYECLKMGGTYSSVLNSANEVLVSE
                     FLEDKIGFYDIPYYIEKTLEVHSSISEPTLEEILETDRWSRAYVANLIKK"
     gene            complement(16837..17040)
                     /locus_tag="ACGI5H_003108"
     CDS             complement(16837..17040)
                     /locus_tag="ACGI5H_003108"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897277.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HFG9698803.1"
                     /translation="MISYAPLWKLLIDRKIKKMEFVNISGISISVLGRLGNDKSVSMD
                     TMEKICLALDCKIEDVVEIKKGI"
BASE COUNT         6017 a         2707 c         2073 g         6648 t
ORIGIN      
        1 aggcattgat taggaagagt aaatctgaat cgattaccag agaaggaaac tactagctga
       61 aatgtttccc taattagaag gattgaaaac tacctaggag cttctatccg aagttatctt
      121 aatgatttta gtaggaatag acgtttttat tacttgcgtt aaagtatcaa gtggattttt
      181 taaaatcaat ttgggtggaa ccgcgggaaa cagattctcg tccctttttt agggatgagg
      241 gtcttttttt attacctaaa ttcagttttt aaaatattct gtatctaatt taattagcta
      301 attaaaaatt taaaatatat ggaggattat aaaaaatgta ttattcaagt acgagaggca
      361 ccgaagaaaa agtaactgca tcacaagcaa taataaaagg aatatcaaat gatggtggtc
      421 tttatgttcc aagtgaattt cccaatgtaa aaaatgaact tataaattta gtaaatttaa
      481 cgtattctca gatagcattt tttgtactta gtaaattttt atgtgatttt actgaagatg
      541 aaattaaaaa ttgtatagaa aatgcatatg atgaaaagtt tgattgtagt agtatagctc
      601 cattaaataa agtaaatgat acttatttct tagaactata tcacggtcca actttagcat
      661 ttaaagatat ggcacttact ataatgcctc atcttcttaa aacatctata aagaaagata
      721 atttagagaa agatgttgtg attcttactg ctacatctgg agatacaggt aaagctgcac
      781 ttgagggatt taaagatata gataaaataa agataattgt attcttccca gaagatggtg
      841 taagcccagt acaaaaactt caaatgaaaa ctcaaactgg aaaaaataca tatgtagttg
      901 gtataaaagg aaattttgat gatgcacaat caggtgtaaa gaagattttt tctgataaag
      961 aatttaatca aaaactattg gataataatt atatattatc ttctgcaaat tcaattaata
     1021 taggaagact tcttccacaa gttgcatact atttttattc atatatgaaa ttagttagca
     1081 atagtgatat aaatttaaat gataaaataa attttgttgt cccaactggt aattttggta
     1141 atattctagc tggatattat gctaaacaaa tgggtcttcc aataaacaaa ttaatatgtg
     1201 catcaaatga taataatgtt ctttatgatt tctttaaaac tggtgtatat gataaaaata
     1261 gaacattgaa attaactact tctccttcta tggatatatt aatttcaagt aatttagaac
     1321 gattactgtt tgaaatatca aatagaaata ctgatattgt aaataagctt ttatcagacc
     1381 ttagtgataa aggagtctac aaaataagtg atgatatgga aaaaaattta gcctcattct
     1441 atggagaata ttcaaatgaa gaagaagtta aaagcacgat aaacaatgtg tttaaaaatt
     1501 ataattattt gatagatact catactgctg ttgcatacaa ttgttatgaa aaatataaaa
     1561 aagaaacttc tgataacaca aaaactgtta ttgtaagtac tgcaagtcca ttcaagtttt
     1621 ctgaagatgt tctaaagtct atagattgtg attttaaaga ccttgatgac tttgctataa
     1681 ttgatagatt atcaagtatt tctaaaatag atattccaaa acctattaaa aatcttaaaa
     1741 atgcagaaat actacataaa gatatttatg aaaaagatga attaaaacta gctataaaaa
     1801 aattcttaaa ggtataggtg attattatgt tagagattat agttcctgca acaagtgcta
     1861 atataggtcc aggatttgat tgtcttggaa ttgcgttaaa tatatacaat aaattttatg
     1921 ttgaagaaat tgaaagtggt cttgaaatag aaggttgtga agatgcttac aaaaacgaaa
     1981 acaacttagt ttatacatct atgaagtact tttttgatag agttaaacca gaaaaaatac
     2041 ctgctggtat caaaataaaa atccaaagtg aagtacctat atgtagaggt cttggcagta
     2101 gtgcctcttg tatagtagct ggagttatag ctgcaaatgc tctatcaggt gctaatttag
     2161 ataaaaatca attactaaat atagcttcag aaatagaagg tcacccagat aatgttgctc
     2221 ctgctatttt aggaaatatg attgtatctg ttactgataa tgagaatata cattatgata
     2281 ttataaaaat tcctgaagaa cttaaatttt gtgcaatgat acctaatttt aagttatcaa
     2341 cagaaaaagc tagaggtgtt ttaccaaagg aaataccata ttctgatggg gtattcaatg
     2401 ttagtagagt tgctttacta atatctgcct tactaaacaa aaactttgac ctacttaaag
     2461 tagcttgtca agacaaattg catcaagatt atagaggaac tctaattgag aactacaatg
     2521 atattgttga aaaatctgaa caattaaata gtattggagt atttttaagt ggagctggac
     2581 ctactataat gtctttaata aaagaaaatg atgatagttt tgtggataat atgaaaaatt
     2641 acctacaaaa actaaaatct gattgggaaa taaaagagtt atgttgcgat tctaatggag
     2701 ctgttttaaa tataatataa ttatcgtctt ctatacaaaa tataactact cttttattat
     2761 aatttgtagt ataataatta ggactaggta ataatattaa gtattataat ctagttcttt
     2821 aaacatgttt acattgagga gggattatca taaaagagtt aataattaga gatttagttg
     2881 caaaagttcc tataattcaa ggtggaatgg gcgttggtat atctaggtca tcactagctg
     2941 gtgcagttgc taagcttggt ggtgttggtg taatttctgg agttcaaatt ggatatgatg
     3001 aggaagattt tgaaactaat actataaatg caaatttaag agctataaaa aaacatattt
     3061 ctaaggccaa agaaatctca aatggtggta ttattggtat taattttatg gtagctatga
     3121 aagaatatga aacatacgta aaggaagctg ttaaagctgg tgtagacctt ataatatctg
     3181 gagctggatt acctaataag ctaccatcat tagtaaaggg aagtaatgta aaaatagcac
     3241 ccatagtttc aactgcaaaa gctgctaatg taattttaaa aatgtgggat agaaaagaga
     3301 aaactactgc tgacttaata gttgttgaag gtccaaaagc tggtggtcac cttggatact
     3361 ctaacgagga acttgataac atagattcta tagactatga taaggaattt gttgaaattt
     3421 taaaggttgc aaatacttat ggagaaaaat ttggtagaaa cataccagta gttgctgctg
     3481 gtggtataac ttctagtagt gatgttaaaa aatatataga tatgggtgca agtggtgtac
     3541 aagttggtac aagatttgtt gctacttacg aatgtgatgc ccatgagaac tttaaaatgg
     3601 catacataaa tgctagtgaa gaagatgttc atatagttaa aagtcctgta ggtcttcctg
     3661 gacgcgccat aagaaacaaa tttatagaag aagttaaaat aaatcgtcca gaaataaaga
     3721 agtgctataa ttgtttgatt ccttgtaatc caaaagaaac tccttactgt atttctcaag
     3781 ctctaatcaa tgcagttaaa ggagatgttg aaaattcact tttattttgt ggaaatgatg
     3841 cctataaaat tgataaatta agtactgttg aagatgttat caatgaattg atttctgaat
     3901 tataatttaa agaaaactaa attaaaattt tatcaagcta aggagtttaa atacgttatt
     3961 tattaatctt tataaacata tttatgtcct tagctttttt gtgtcaattt ccttttatgg
     4021 aaattttaat ttaattagag atagtattaa cctttataac taatcttctt ttacaagtac
     4081 attggttatt tcagctatat ataaagtatg ataatctttt tgtggatacc atcttccatc
     4141 tataccttca gcaataaaac attgaggttc aagtttctga ctatacattt ttttgcatat
     4201 aatagccatt ttagattctt taaaataagg tgtatcattt aagtgttcta tattaaatcc
     4261 aatctgtgat atcttatcct cttctctacc agataccttt ccacaatatg aaagctcttt
     4321 acgaaaatct tcatcaaaaa atgtaagaga aaatttatct gtattatcta taaattcctt
     4381 agtataacgc tgtggtctta ttactacaaa agcaacatct tttccccaca taactccaag
     4441 ccctccccag ctagcagtca ttgtattcac tttaccttca ttttctgctg ttataagtgt
     4501 ccaatcttta cctatcaatc caaatggatt atttttaatc tcttctgcca aaatctcttt
     4561 aaaatcactc atatctctaa taacctctca ttctcttata tttatattcc ttttattttc
     4621 gtgataaatt ataaatgaag tctagttttg aaaataaaat acttttttaa atatattatt
     4681 gcaaataagt aaatatatat atactctctt attttttaat atatttaata atttcactca
     4741 gaatatatat attctttact caaattaaat ataacttata tactttatgt gtaaattatg
     4801 gtaaaaatat tatttaatca aatcaaaact tgatttatat acctggaaaa ggtattatat
     4861 taaagagtgc ttaaaatacg catttcataa atagctatat ataaaataat aaataaggag
     4921 agtgatgggc aatggatact agtccgttgc ggagagaatt ttttacattt tcatcactta
     4981 ataatatcta aaatcaaaac taatacatat attcagttat ataaattagt taattaatag
     5041 atactattaa atgatgagat ttatataaaa ctgaataaag gatgtgttgc catgataaga
     5101 tattacaaaa ctatagattc aaaattagag aaacttagtt tttttgaaga tggctgttgg
     5161 ataaatcttg ttgaacctaa tcatagtgaa atcaacgaaa tttctaattt attaaatata
     5221 gatgtagaaa gcatagaatc tgcactagat gaagaagaac gctcaagaat agatgttgaa
     5281 gacaatcata ctcttatact tatagatata ccagtagacg aaagtgactc taattcttct
     5341 cattatacta caataccctt aggtattata ctaactgaag aagctattgt aacagtttgt
     5401 gatgcacaaa ctaagatttt aaatgacttt atagttggtc atattaaaga tttttttacg
     5461 tttaaaaaga ctcgcttttt gcttcaaatt cttcacaaaa atgcagctta ttacttgcat
     5521 tacttaagaa aaataaataa aatgacaatc ataatagagc gagaaattta caaatcaatg
     5581 aaaaacaaag aattggttca attattggaa ttagaaaaat ctttggtata cttctctacc
     5641 tcactaaaat ctaatgaact tgttttaaac aaaatggtta gaactgctgg tataaagaag
     5701 tatccagatg atgaagacct attagaagat gttatagttg aaaatagaca ggctcttgat
     5761 atggctaaaa tatatggaga tatattgagt agaattatgg atgctttcag tgcaattata
     5821 agtaataatc agaataatgt tatgcaaatt ttaacagtag ttacactaat tttctcaata
     5881 cctacaataa tatcaggatt ctttggtatg aatgtcatca acatgccatt ttctaataac
     5941 ccaaacggat tttggataat acttcttatt acctctataa tatgtatagt gattacattt
     6001 ttcatgtcaa gaaataagct attataaaat attaataaaa aggccattag aattaattga
     6061 tttacattta tcctaatggc ttttatatat ttaaatctat ataatcttat aatacttttt
     6121 aactatcatg ttcttcatct ataatcattt cagtttcaag cccttctagc attgaatcta
     6181 aactttcttt tatatttagt atataaattg gtacatactc ttcttcatct attacctctt
     6241 cttgcaactt aaatggagga attaatactt catcaaagtc tatatttaaa tttggaaagc
     6301 cttctactat ctcttcacaa ttatcgtact cttcatttgc taaagaaatg tacatatcta
     6361 ggctcttttt ataataaaga cctgcaagca tatactcaca cttcttactt ccatatttaa
     6421 taccttcttt ataatatttc tcagcttctg cgtcatcatt taattttaaa taaatttgac
     6481 ctaaattata tattgattca acacaacctt gtgctctagc cttttcatac caaaatttag
     6541 aatttacata atctttatag aacatatcat aaattaatcc taccatatgt tgagcataca
     6601 cattattttc attggcaggt gtatcaaaca tcattttaga ctcttccaat ttaccttctc
     6661 taaaataaat tctacctaga tgtatacgag cattcatatg gtttttgcta cttgccattt
     6721 caaaatactt tctagcattt tttgtatttc ctaagctctc atatatacac cccaatctat
     6781 aactagacct cgtatctcca ttttcagatg ctttcttata ccaacttatt gcttcttcaa
     6841 tattatttaa atcttcatag atatttccta atttgatttg acaagataca ttatttggaa
     6901 tcctcgaata atacgaaatc gctttttcta tatcttgatt ctgataatat aaatccccta
     6961 gattttcaag ggaacttttg catccaacag ctatagcatc ctcataatat ttaatagcat
     7021 tttcataatc tttttcttca aaatatatac ctgccagatt attttttgct tctgttatat
     7081 catcttcagc agccatttta taataagttt ttgccttctc tatctcattt tctctattat
     7141 ataaattagc aagtctatac ttagaaagtg tatgattttt ttctattgct ttctcataat
     7201 aataaattgc atctcccagc tcttcttttc tatcatatac atatgcaagc ctatactcag
     7261 acttcacatc atctctatca gcactctttt tataatactt ctctgcatct tctaaattat
     7321 catttatttc cataatcata cccaagttaa agcaaccttt catatgacct gacttgtaca
     7381 actgtttata taaacttact gttgatttat tatctttctt ttttccattt aatattgcta
     7441 aattatattt tgcatcatca tctaaaagca cagaaccttt tttatagtat tcatatgctt
     7501 catcatcttt ctccaaaaaa gtatataata cccctaaatt aaaacaagct ttacctaaat
     7561 tcttgtctgc tgctgttttt aaccattttt cacaccttac aaaatctttc attttaaaat
     7621 ggcatacacc taaattattt tgtgcttgta aataacctaa atttgctatc ttttcatacc
     7681 aatatatagc atattcatag ccatctaact tatagtacat attacctaaa tcaaaagcag
     7741 catcttcact tccactttta tatgccatcg aataccactt ttctgcttct ttaaattgtt
     7801 ttttactttc atatatattt cctaaagtat attgagattt tacgtaatta tccaatgcag
     7861 cactcttata caactctatt gcgctttcca tcttacccat cttttcaagg agggcaccct
     7921 tagtatgtac gactttcggg tcattagata tattttttat tttttttata gaaaattttg
     7981 tatttttcat tattcgctac ctacccattt tataaaatat attctctcaa acattattat
     8041 acattataat ctacaattaa tgctataata ttgaattttt accttttgtc actatattgt
     8101 aacattaaat tttaaatttt ataatcatta gattttatta tgtaattggt atataatgta
     8161 tatatagggg ggacatttta tgaatttcag caatattttt atccaagttg cagttttatt
     8221 tataattatt ttagttggat attttgtcag aaaattcaac ttattagatg accactgcac
     8281 atctaagctt tcaactttga caatgacagt ttttttacca tcaatgataa ttagctccat
     8341 gcaaattaac tttgatagta aaatgataca aaaaatacta ttgttattat ttacatcttt
     8401 gattatgtat atagtttcaa ttataattgc atttttattg aaatacattt taaaatgtaa
     8461 tgataaaaaa gatttgggaa tataccagta tatagttgtt ttttcaaatg ttgcttttat
     8521 gggttatcct gtaattgaag cagttttagg tcatgaagca atattctata ctgcaatatt
     8581 caatttgcct tttaacttat tttctttcac tttaggaatt tatcttttat ctaaaggcag
     8641 tacaagtaga ggtttttcaa taaaatcact tataagccct gctacaatag ctattgttat
     8701 tggacttttt ttatttgtaa caggacttag gttaccccaa tttataaacg agccacttga
     8761 gatgttggga agtataacta caccaatatc catgattatc attggaagct tacttgctaa
     8821 ttcttcagct ctcgattgtt ttgtcaacaa aaaattatat atagtcactt ttataagatt
     8881 attggtactt cctgtgattg tgtattttat tctaaaagga tggataaatg ataagatgat
     8941 tttagctata ccagtagtaa tttcttcaat gcctgctgct gcaaatactg ctataatggc
     9001 taatcaatat gactccaata taacactagc ttcacaatgt gtgtttttta caacactatt
     9061 ttcagttata tctatacctt ttataagtat tttactctta tcttgattta tttttttatg
     9121 tattatataa taacatattc aataaattac aaatataaac attttattgt agtatattga
     9181 tggaattttt tcctagatat ttgtcaataa tatctatatg tattatagaa taggaggctt
     9241 aaatatggat atggatttac tctttaaaat agtatttgct atagttgcta taggtgtttc
     9301 tgtaaaaatc attaaaactg ttgctagttt agcttttaaa atagcgttga tattgctaat
     9361 aattttattt gtatatagaa tgtttttgta aacatttaaa aataagtttt ttaacacaat
     9421 agagaagtaa aatagattat ctttaatgta aattttttat taaagacact ctattttact
     9481 tctctattag cttctttaaa ttaaattttt attatatctt cccataatat aaacatcttc
     9541 aaattttcca tctctgatta cagcatattt tttagttccc tctatttcaa aacctagctt
     9601 tttatataaa tttaatccct tttcattatc cacaattact tctaatccta ctctagttaa
     9661 cataatccaa ttatctgcta tatctaaaag ttgttccata agcttcttac ctactcctct
     9721 tccctgataa ttctctgcaa cacttattcc tatttctgcg ctatgtctca atcgtggaga
     9781 agaatttaca tgtaacccag caaaacctat tacatctttt tctccattat tattagtttc
     9841 agctacaaac atataatcat tttctcccaa agaagctaac atagcttcag ttttatcgac
     9901 tctgtcactc attaatgcca aagtatttct cataacactg tatgttcttc taatttcatt
     9961 aaaagcttgt gcatcttctc ttcttatagg tcttattgtt atatctatag gcttactcat
    10021 attggattcc ccctcaaaca taatctttat ttttaattaa aattttacat ctttatttta
    10081 tactgttcaa atctatgtat gcttctacct gaggtacata tatcatatta tcttttatat
    10141 gtgtacttcc aaattctttt aattctgtac cttctttatc cttagttatt ttatatctaa
    10201 tggattccat accttcaact acttcagcat gaaaaaacat accttcatat tgtttaaatc
    10261 taaaattaaa attgtcttta gtaagtttta ttatcatatt tttatctact ccttatataa
    10321 ttgatatttt tcttattatt agttgtatat atactgctta ttcatattaa tatattataa
    10381 cttatcattt atttagtata aagttataaa tagatatatt tatacttatt ttacaatctt
    10441 tcttcaattg atatataata tgtttatata aactaatgta tgtgaggtga aatatgagca
    10501 aaaaaacaaa atatttttct ttaattctct ttcctattgc tttgctttta aattttatag
    10561 ccagtaaagt tccaaatatt gttgaaaaat attactccca attcatagat aaaataattg
    10621 tacaaatatt gagtaaagtt tctggaattt tcccattttc tctctatgag attacaatgt
    10681 acataatagt tatatctacc ttcttatttt tatgttgtac tttatctaca atttttaata
    10741 agaaaaaaaa attaaacata tatttaaaaa attccatttt aaatatatta tccattgtat
    10801 caatagtcta ctttcttttt gtagtgcttt ggggaataaa ctataatagg attccactag
    10861 aaaccacact tataaataac tataatttaa aaaacaatac ctctatccaa tcaaaacaat
    10921 atagtgttaa agagcttact aaattatata aattccttgt aattaaagca aatgaaacta
    10981 gaaaactcac attacaagat aaaaatggta ttgtaaaatc taatacagat tataatggtg
    11041 tcataaatag agctcaacta ggatacgata atatcttgga tatattacct ggtgttagtg
    11101 atagttattc taagcctaag tatattattt catcaaatct aatgtgctat acaggaataa
    11161 ctggtatata ctttcctttt acaggtgagg caaatgtaaa tatagcaata cctgacttat
    11221 atattccttg tacagttgaa catgaaatgg cacatcaaag gggatttgct agtgaagatg
    11281 aagctaattt tatagcgtat cttacttcta taaaacaccc caatattgat tttaactatt
    11341 ctggatatat tttagcttta aattatactg cttctgcttt aagtaaggtt gattataatg
    11401 catatgttga tatttctgct ggcatttcag attctgtccg tagagattta aaaaatgaaa
    11461 gtgaattttg gcaaaaatat gaaggtaaaa ttaatgaaat ttctaatgag tttaacaatt
    11521 cttacttaaa agctaatggc gttactgaag gtactcagag ttatggtaaa atggttgatt
    11581 tattgctaac ttattatgaa ttatatccat ataactaaac actacaattc aaaattttat
    11641 tcatatacag ctgatattaa atcagctgtt ttctatttaa ataaattatt taacttcaag
    11701 caatcttata taatttgata gtacttatac tatctgtata acatttcaat tctaactatt
    11761 ttagttaaaa catttctatt atctttttta ataaatgttt taactaaaat ttttaaaaca
    11821 taaaacttcc acattatttc actatctata taaaaatcta aaaattcaca tataaaatta
    11881 cataactaaa aaatcataaa tttatagaaa acatatattc aaaataaaaa agcatgtatc
    11941 aaaacttgac acatgcttat aatcttatgt atatatatca ttttgtcaca ataaaaattt
    12001 acttgtaaca ctgatatttt taaacaaaat agtccttatt taattaaatt aacattaatt
    12061 aaattcgtac tcattttgct atcattaaac attacttata gtaattttct aatacactat
    12121 ttgaaacttc cttcccttga aaacttttca accaattctc atatgctgag tttttccata
    12181 cactaccatc attaaatgtt acttgtttta cacaagatat aatgtacttt acaccatgct
    12241 ctccagttga ttgtttccat ttatcaaaca atagaaaggc atcattttga ttcttacctg
    12301 gtgctattgc attttgcttt gcatattctt tctccatttg tttccattct ttcaaccaat
    12361 tttctaccca tgccttgcct tgttgttttt caaacatact tattatatcc tgtggtggtg
    12421 attgttgcat ttttctataa gtatgtgaat atgattttgg agacacagga gatatgcctg
    12481 taacaatacc atagtctaca ccagctgggc taaatccaac acttcctact tcgccatctg
    12541 ctgccacatt ttgagcatcc caatatagct caagtggttt tccattttta tcatatgcta
    12601 agcatgtaat ttcataatcc ataattgcct tttcactgct atttgttaag cttataacat
    12661 tgctaggcca atgatatgga gtatcatcat actgtatttt gctattattt ataaataatg
    12721 gaatattctc attataaaca agacctttac tactttgaat atctgatacc ttctttgtga
    12781 cagtacttac cgtatttgct aagtatacat ttgttttttc tgaattggtc gtactaagag
    12841 aaaatgttgt tgtcgttcca gtaatcagca aagcaacaac taaaataggt aagctagata
    12901 tttttttata tctcacaatt cttcacctct ttttctatta acttataata aaacaattta
    12961 ccaaaacatt aaaatctatg ttaacataat ttaccaactg ttctagtaac tatatcctat
    13021 catagttact atcaagtttc aatactattg atggaaattt tcactatatt aaatcttttt
    13081 ttaattttat aaatttacaa tatgatttaa ctcatacata tatagtcaaa ttagaatata
    13141 agtttcttac atttaatgaa gtttataaaa taaaaaatga ctagataatt aaatactgta
    13201 aataaaaact tattacaaaa gtatttaaaa atctagtcat ttaatatata tatgaattgt
    13261 atactataat ttttcaatct cttctagcaa ctcatcaact aatttgttac catcaatcat
    13321 tctaactatt tcaccctttt taaataaaag accttcacct ttacccccag caatacctat
    13381 atctgcttct ctggcttcac caggtccatt tacagcacag cccataattg caacagtgat
    13441 atttttttcc atactaccaa tcttttcttc aacctcattt acaacactaa ttaagtctat
    13501 attacatcta ccacatgtag ggcatgatat aactttaatc ttatcattta aaagtcccaa
    13561 acttcttaaa atctgtttac caacaataac ctcttcaaca gggtcgcctg ttaaagatat
    13621 tctaacagta tctccaattc ctttaagaag aagtgctcct acccctatag aagactttat
    13681 tgttcctttg tgaacacttc cagattctgt aattccaata tgaagaggat aatcaacttt
    13741 ttttgatatt aattcatatg catcaacagt tttataaata tcggatgatt ttagagatat
    13801 aactatatta tgaaaatcta agtcttcaag aatcttaata tgtcccattg cactttcaac
    13861 taatgcttca gcagttgcag agccatactt ttttaaaagt tctttctcta aagaacctcc
    13921 attaactcca attctaattt ttaaatttct ttccttgcat ttctcaacta ccatcttaac
    13981 tctctctata cttccaatat taccaggatt tattcttatt ccatccacac cttgttctat
    14041 agcttcaagg gctagcttat aatcgaaatg tatatctgca ataattggta tatttacact
    14101 agactttatc tttgctatat ttttagcagc tttaatatca ggaacagcaa ctctaactat
    14161 atcacaacca gcttcctcta atctctttat ttgagctatt gtagcatctg catctcttgt
    14221 atcagtattt gtcatagatt gtatacttat aggattttct cctcctattt ttacagctcc
    14281 tacacttact tctctcgtct ttcttctctc gtaactcata ttccacctct atatattatt
    14341 ttatattgaa tctctttaaa tattaaaata ttataaccta catgtatatt ataaattaaa
    14401 aagctatcta gttaaataag aataaatttc atatataaaa attaatttat tcttatttaa
    14461 aactacatag cctattttct taaaatctct aaaaaactaa atcattgaaa taatcttagt
    14521 atatctttat atgtgataaa aagcataaat aacattaaag ctccaaaacc aacaacattt
    14581 atcatgcctt ctttatttgg gtcgagtttt ttaccacctc taacagcttc tagtaacaac
    14641 ataagtattc tccatccatc aagtgctggt attggtaata gatttactat acctaaattt
    14701 aagcttatga cagctgctaa atacactaca tttatgatgc ctgtacgagc agcatctgat
    14761 accataccaa taacacctac tggtcctgct acagcattgc caatccctcc tggtacacgt
    14821 cctgtaatca tttgacctag aaatgttagc atctgttttg tcatatctac agtagtttta
    14881 catgcattta ctattgaccc taaaaagtct ttttctcttt gtggttgaat tcctatttca
    14941 tactttccat tgttattttt aggtgttaca tttacaactt tatcacttcc atctctagtt
    15001 atactaagtt ttaattctcc accagaagaa gtgtttatta tatttgcaac ttcatcccaa
    15061 gtcttaacag aattaccatt aattttattt atcttatctc ctacttgaag ccctacagcc
    15121 tgtgcaggag tatctggcat tatctttcct aatttagtcg ttggagaacc tatatacaaa
    15181 aatactggaa ctaaaagtat tgctgctaat attatattga atattggtcc tgctacaata
    15241 gtactaaatc tttgtaatat agacttgttt ccaaaagaat ttggacttat ttgttcttca
    15301 tcttcacctt ccatgctgac atatccacca attggaagtg ctcttataga atactctgta
    15361 tcttttttta cactatatat cttaggcccc atacctatag aaaactcatt tactttgata
    15421 ccacttcttt ttgcaaatat aaaatgtcct aactcatgta ttaatacaat tatactaaat
    15481 agtattaatg cggctattat agtcataaat tcaccttcct atttttttat cagatttgca
    15541 acataagctc tactccatct atctgtttct aagatttctt ctaatgttgg ttcacttatg
    15601 ctactatgaa cttctaaagt cttctctatg taatatggta tgtcatagaa accaatttta
    15661 tcctctaaaa attcacttac taaaacttca tttgctgaat ttaaaacaga agaataagtt
    15721 cctcccattt ttaaacactc atatgccaat tttaaacatg gaaaagtttc taaatctggt
    15781 tcttcaaaag ttaaagtact aaattttgaa aaattcattc tttcaaagct actttccatt
    15841 ctatctggat atgtaagagc atactgtatt ggtagtctca tatctggaca tcctaattga
    15901 gcaattattg agctatctgt atactgcacc attgaatgaa ttatgctttg tgggtgaact
    15961 actacatcta tattttcttg ttctactcca aataaccatc tagcttctat cacttcaagt
    16021 cctttattca taagcgttga agaatcaata cttatttttc ttcccatact ccaatttgga
    16081 tgcttcaaag cttcattttt agttatattt gcaagttctc cctttttctt tcctctaaat
    16141 ggaccaccag atgctgtaag tattatcttt tctatatttt ttttattttc tccatttaga
    16201 cattgaaata tagcactatg ttcactatca acaggaagaa tatttacatt gtatttttct
    16261 gcttctttca ttacaagttc accagcagtt accaacgttt ctttattcgc taatgctatg
    16321 tctattccct tctttatagc acaaagagtt gggactaatc ctatcatacc tactacagca
    16381 gttaaaagga catccacttc atcaagtgat gatattattt ttaatccttc cattcctgct
    16441 aaaacttcta tttctatatt tttaggcaac atttctttta attttaatgc tttattttcc
    16501 tcaaaaactg ttacatattt aggtttaaac tctactatct gttctagcaa taattcaata
    16561 ttactgttag ctgatattgc aactatctca aacttatctc tatgttctct aaccacatcc
    16621 aaagtttgtt tacctataga gcctgtagaa cctaaaattg atatcttttt catataataa
    16681 tcctttctaa taataaatat accctgtcaa aacattataa cactactaaa acaattattt
    16741 ttactattca tagaaatttc atatattatt ccacagatta aaattaatct attatttttt
    16801 gtattttgtg gaatattata aaatattcta gtattattaa atgccctttt ttatttccac
    16861 aacatcttct attttacagt ctagtgctaa acatatcttc tccattgtat ccatagaaac
    16921 agatttatca tttcctagtc tgcctaaaac agaaatactt atacctgata tatttacaaa
    16981 ttccattttc tttatttttc tgtcaattaa caatttccat aatggagcgt atgaaatcat
    17041 gttatcacct cgcaaaatat attctatcac attttatcta ttttggaaaa ttttcatcta
    17101 tttagataaa taatcacctg cttaagtgtc aaataatttt atccttctaa tatgaaaatt
    17161 taatactata ctaaatgatt ggtatataac acatatgatg cattattatt aacatataaa
    17221 aatttttatt ggtgctaaat taaagtaata tactattatt atatttgcag atatataaga
    17281 aagattttat tatatattta aagtacttga ttataataag agacaagggc tatgatggat
    17341 actatagaaa gttagaacta tactatttta gaatgaacaa ttaaaataat taaaattagt
    17401 ttaatctttt attcttgata aaatcatatt aaataaatac aaaaa
//
LOCUS       DAYAOO010000087        17318 bp    DNA     linear   BCT 12-OCT-2024
DEFINITION  TPA_asm: Clostridioides difficile isolate ST8-SSI-h139-18
            SAMN40601845-rid21577343.denovo.087, whole genome shotgun sequence.
ACCESSION   DAYAOO010000087 DAYAOO010000000
VERSION     DAYAOO010000087.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN40601845
            Sequence Read Archive: SRR28438827
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 17318)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 17318)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-MAY-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-MAY-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002157583.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002157583.1
            Genome Coverage       :: 163x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/11/2024 16:19:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 4,038
            CDSs (total)                      :: 3,963
            Genes (coding)                    :: 3,930
            CDSs (with protein)               :: 3,930
            Genes (RNA)                       :: 75
            rRNAs                             :: 6, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 60
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 33
            CDSs (without protein)            :: 33
            Pseudo Genes (ambiguous residues) :: 0 of 33
            Pseudo Genes (frameshifted)       :: 7 of 33
            Pseudo Genes (incomplete)         :: 25 of 33
            Pseudo Genes (internal stop)      :: 11 of 33
            Pseudo Genes (multiple problems)  :: 8 of 33
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..17318
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN40601845-rid21577343.denovo.087"
                     /isolate="ST8-SSI-h139-18"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Denmark"
                     /collection_date="2018"
                     /collected_by="Statens Serum Institute"
     gene            99..2168
                     /locus_tag="ACGI5H_003109"
     CDS             99..2168
                     /locus_tag="ACGI5H_003109"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728763.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HFG9698804.1"
                     /translation="MQLTKIILSNYRCFGEEPTTIEINNLTGFIGHNSSGKTALLSAL
                     MKLFGEKSSDRIIERSDFHIPESIDPDSISKNELYIEAQFEFPELERGKDSISIPVFF
                     KNMVVSEPGGKPYLRIRLEANWEKSSNPEGSIDSNVYYITSTTEEINPEDKRNIKRYE
                     LDQIKMIYVPAIRRPDEQLKNVSGTIISRLLNGISWSEQTKARIKTKASETEEIFFEE
                     KGVESLKKSLETQWNSYHKDIRYSNPKINFNSTDLETILKKVEVTFSPTGTHRDYRVE
                     ELGDGLRSLFYLSLVNTFLEIEEEILKSINDGKEEDIFTLIPPVLTIVAVEEPENHIS
                     PHLLGRVVEKLNFISTKENSQTILTSHSPAIVKRIEPTDIRYFRICKEYECTKVKSII
                     LPNEEKEAEQFKFVKESVLAYPELYFAKLVVLGEGDSEEIIIKQMIELKAESVDSSEI
                     SIVPLGGRHVNHFWRLLNDLEIPFITLLDLDRERDGGGWGRIKYAIQQLINIGHDKNV
                     LLYTCEGISQDNEFKEMHTWDVTDTENMAKWIEMLKGYDVYFSAPLDIDFAMLQSFKD
                     KYISALTSAEGPRIKDHGKIQDIVINEDAEDESLKAAYKDRIDSDIKSTLKQEGGDGS
                     TYTEGEKELMIWYSYFFLGRGKPTTHLSLFSNNTDIDFESFPYCLKEFVNSIIEKMID
                     DSGGGRK"
     gene            2165..4030
                     /locus_tag="ACGI5H_003110"
     CDS             2165..4030
                     /locus_tag="ACGI5H_003110"
                     /inference="COORDINATES: protein motif:HMM:NF012789.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent helicase"
                     /protein_id="HFG9698805.1"
                     /translation="MKRNWVSKEDWSPAAGFRLEVEAMNTVINDKNTLVVAGPGAGKT
                     ELLAQRACFLLETNTCRYPKKILAISFKKDAAENLKERLELRCGKELASRFESKTYDA
                     FAKEIVDRFRNSLDEAYRPLNNYNIAENRDVRRAFEIAGLNFRGNQTEFNKVYGNKLS
                     INKLPLHTDFVDKIFIDAWNVLLKGNKDTNFVSSLTFGMISRLAEYLIRTNRYIKKAI
                     EMTYSHVFLDEFQDTKSIQYDLVKACFFKTETIITAVGDGKQRIMLWAGARKSIFEDF
                     QNDFLSQKRTLIMNHRSAPRLVEIQKAMYNSLNEEAIDLKTNEKWNYEDGEVYLRLFE
                     DYIKEADILSEEIVELVETGIEINEICILVKQSVDIYSKEIINKLSERNIKARNEAMY
                     QEILKEDIIKTLVSLFRLSLSDRNPDDWDYIYDILGELYGIDEGYNPKILNDFITKVE
                     LMINDLKVNLNITDEKQFSDLVDSKVEYISYEKFASKFQKYKSKDYFDDLVDKFKKLV
                     WIEYNETKDWIKAIDNFEGKNSIPIMTIHKSKGLEYDTIFFVGLEDSAFWNFKNQPDE
                     DRCAFFVALSRAKRRIDFTFSLDRPAGFSNSQKHYCINEFYELFDNTEIVKKIEY"
     gene            4154..4348
                     /locus_tag="ACGI5H_003111"
     CDS             4154..4348
                     /locus_tag="ACGI5H_003111"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9698806.1"
                     /translation="MKKKTKISKKIVSFIMVFITIVTTILTSSVSAYASELDMSEQTG
                     FNYLGISPITGKKLIITFIV"
     gene            4351..4968
                     /locus_tag="ACGI5H_003112"
     CDS             4351..4968
                     /locus_tag="ACGI5H_003112"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9698807.1"
                     /translation="MDNKIVFCVEPGIKTSSGGGYISEELGDKFISTTLPNYHKRKAE
                     ILEKVNRHNILPSWNNEKVAVKSGETIELEDKNGIIREMQLESNNTGTDILLEENTLK
                     ITANKNSNSGVISYIKIPKNEVGISIVYRKHNYQSLSEFHMESSMSANLNINVIKLGI
                     VKVKKIDEGTGKELANAKLRFEYDGDSKEIITGSNEIASIEDIIG"
     gene            4960..5481
                     /locus_tag="ACGI5H_003113"
                     /pseudo
     CDS             4960..5481
                     /locus_tag="ACGI5H_003113"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009901831.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003916 - DNA topoisomerase activity
                     [Evidence IEA];
                     GO_process: GO:0006270 - DNA replication initiation
                     [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiation factor domain-containing
                     protein"
     gene            5594..5755
                     /locus_tag="ACGI5H_003114"
     CDS             5594..5755
                     /locus_tag="ACGI5H_003114"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9698808.1"
                     /translation="MAIAIIGVYLGFKREFSKLIGFLVVALIAVGLVFNTAGVKDILL
                     ELFNKIIGV"
     gene            5995..6222
                     /locus_tag="ACGI5H_003115"
     CDS             5995..6222
                     /locus_tag="ACGI5H_003115"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HFG9698809.1"
                     /translation="MDIVKVFANNVRKYRNKKGLSQEAFAEKAGLHRTYICAIERKKR
                     SIALDNVQKIADALEIETYLLFIEGEEKECL"
     gene            6219..9158
                     /locus_tag="ACGI5H_003116"
     CDS             6219..9158
                     /locus_tag="ACGI5H_003116"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728760.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0008170 - N-methyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="N-6 DNA methylase"
                     /protein_id="HFG9698810.1"
                     /translation="MKKLPIEKLIENLGFSGSKNLVNIDMLTKLDISKHDVKTLKVIN
                     PYAIYLVNSKPFILFIESSFEEKKLQQISKLIWNAQIPIAFICDSNSVKIFNGKALDL
                     KSYLIEEIYNQSIEDFSEESEFSYLKISDPLFWDQYTKQYTKTHLNDYLLDNITSLTN
                     KLKKKYKVKFATKLVLRLIFIRYLIDRGVDIAYKNFNHDIKASQKELLKITKNKVELY
                     ELFKYLKEKFNGNLFELNDEINNTCLTDEVFILLSDFLSGKISIDNGQMSLFSMYDFN
                     IIPVELISNIYEILLGKEIRNKDNAFYTPNYLAEYILDKTTLEFLKNNRQYKILDPSC
                     GSGVFLVNSFRRIIDMNLGDKLFCEDDKLLKELLLSNIYGIDINEDAIDVTIFSLYLT
                     ILDYKDPKILSEFKLPNLKGCNLIASDFFDDNKLESLKKINFDFIIGNPPWGSVSDGL
                     HLDYCNKNGYNDMQQNKEISRSFIFRAKDFSSRNTVCSFVVHSKILYTQKKPSKKFRE
                     FLLKKSQIFSVVEMSSVRKLVFKNADAPAAVISFKYNESEENLNNRIIYTSLKPNVFF
                     KLFNIIVIEKYDVKYISQKLLLENDWAWKTIVYGFSKDIDIIMNIKKKYQTVNEIILK
                     NSFVHGTGIQINGNESHDATHLKGKWYVDSKKGIDSFYVDINKGKELTQDKMRRPKAN
                     QQEIFIPPYVLLKKGVDTKTYRYRAAFSNDAFVYSDAVTGICGKKDNLTTLYCLTGML
                     NSSFYSYLNIMLGTSIGIEREQGFSTEIFTYPAIESDEIANLVVKIQEATKLEKTTMF
                     LNEKNSCKYIKQLDKLILKSFNLNDDKFIDYAINIQIPELTNSKSTNIYRKITKEDLI
                     NYSECFKEQFSSIYRRVGKSISISVYPKILNRFTVFELEVTDEKTDREIMVKAEADNN
                     MELFTKIIRYDYNDVFHQIRDIIHFGENSFYIIKPNCYKYWHPAIAEMDLADVLDQIL
                     SDTGGEE"
     gene            9158..9832
                     /locus_tag="ACGI5H_003117"
     CDS             9158..9832
                     /locus_tag="ACGI5H_003117"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434621.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9698811.1"
                     /translation="MGGFKNSSLNFYLKQGLYEIIIDGLIDCCLLMSKSCIEQSRKIL
                     NHEEKIRTHLVENYLENDIERRKTSLSKQHLRFEVEAQENYDNKNESYEGRVDIKVIS
                     KDTLADRRAYYIIECKRIDGKETLNKKYITEGVQRFITEKYSSHYGKNIMLGFIVKDI
                     NIQSNIQKINSLNQNILYTYIDTDMLTVRSDSENNYAVCESKYKVKSKLLLLNHIFYN
                     FSSIIR"
     gene            9993..10409
                     /locus_tag="ACGI5H_003118"
                     /pseudo
     CDS             9993..10409
                     /locus_tag="ACGI5H_003118"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003455547.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
     gene            10369..12816
                     /locus_tag="ACGI5H_003119"
                     /pseudo
     CDS             10369..12816
                     /locus_tag="ACGI5H_003119"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335929.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
     gene            12956..13378
                     /locus_tag="ACGI5H_003120"
     CDS             12956..13378
                     /locus_tag="ACGI5H_003120"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434642.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9698812.1"
                     /translation="MRLEDIIDKESYEEKYDDLTVEIKKLSKEKKTLKASLINEKSIK
                     ARLREFRKILERNELLEKFDRYVFASIVDKVIVGVINEDGIVDPYKITFVYKTSFDDK
                     QDGHKFINKSPLETYSKDNNDNKKKCSYTNNETLRDCS"
     gene            13916..14950
                     /locus_tag="ACGI5H_003121"
     CDS             13916..14950
                     /locus_tag="ACGI5H_003121"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426227.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YHYH domain-containing protein"
                     /protein_id="HFG9698813.1"
                     /translation="MFKKKLIAVAMSITMISVGSFSYAHSGRTDSSGGHRDNKNKSGL
                     GSYHYHCGGYPAHLHNNGGCPYTGGGSSSGTTTSVNNEEKQKRSVGEKGYNQGYEDGY
                     KGNYSSSNYSGDYSDTYESKYSEGYEKGKAKLEEEEKVAKETGYNLGLTGAKSNNTYE
                     KEVLKNAYDTGYSTGYNEYKTKKIEEYKAKGIEDSNKDKEKMTFEENIDSEFIDAYNN
                     AYDEIQEQLKNDYTTQGFESAIKGERFDTSTIGNVKYANWFKEGYDNGKVKLPKAKES
                     VYNQGYNEEDFSIPDEMKSIETKLKGVYDEGLEKREEEKSRNATYGVGAGTAAVVAGV
                     VYKKKKRKKI"
     gene            15037..15240
                     /locus_tag="ACGI5H_003122"
     CDS             15037..15240
                     /locus_tag="ACGI5H_003122"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426228.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4236 domain-containing protein"
                     /protein_id="HFG9698814.1"
                     /translation="MGFNFRKSINLGGGLKLNLGKKSVGISAGVKGARVSVNSKGRKS
                     ATLSIPGTGISYTKTSTKKRKPK"
     gene            15411..16571
                     /locus_tag="ACGI5H_003123"
     CDS             15411..16571
                     /locus_tag="ACGI5H_003123"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860809.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall-binding protein Cwp27"
                     /protein_id="HFG9698815.1"
                     /translation="MKLSKILLAIGMSVSLLIASCPTSNALSSINSIKGTNKYETAGL
                     IADKQNYDIAILINSENGLSDGLSASGLSGAKNAPILLTKKDTIPSETLKRLEKVKEV
                     YLIGGKNSIGASVQKILSDKKISINRISGTDRIDTSHKVAKEIGRVSTVKKVILTNAF
                     KGEPDAMSVASIAVRDKSPIVLTDGNTTSFATDGLETYAIGGKVSMSDKLINETKATR
                     IGGVDRYDTNKQIINKFYNGSKEFYIASGTDLVYSLVGSTIAQKTPIVLVGNGSNKSI
                     LKNASKITAIGNIDDVVIKQCLNITNNVGDSNTGIVKDTNSNNTNKPSNEPSSNNPGL
                     TDKSTVYVTPNGKSYHLTKNCSTLKRSKTINKVTLKQAKSQGKIDPCNVCVK"
     gene            16830..16970
                     /locus_tag="ACGI5H_003124"
     CDS             16830..16970
                     /locus_tag="ACGI5H_003124"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426234.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9698816.1"
                     /translation="MENLMMSIITGVIASYIYDKLKSHSERPTKSGWELNIKFQKSKS
                     SK"
BASE COUNT         7093 a         1678 c         3004 g         5543 t
ORIGIN      
        1 ataatagaaa tattttagca taagatgtat aataaaggaa aaaatacaga attaaaaaac
       61 ataagataga taagtggact taggggagag aaattattat gcaattgaca aaaataattc
      121 ttagtaacta taggtgtttt ggagaagaac ctacaactat tgaaattaat aatttaactg
      181 gatttatagg tcataatagc agtggtaaaa ctgctttatt aagtgcactt atgaaacttt
      241 ttggagaaaa gtctagtgat agaattattg aaagatcaga tttccatata cctgaaagta
      301 ttgatccaga tagtatttct aagaatgaat tatatattga agcacaattt gagtttcctg
      361 aattggagag aggtaaagac agcatatcta taccagtatt ttttaaaaat atggttgtta
      421 gtgaaccagg tgggaaacct tatttaagaa ttagacttga agcaaattgg gagaaaagct
      481 caaatcctga aggaagtatt gattcaaatg tatactatat aacatctaca acagaggaga
      541 taaatcctga agataagcgt aatatcaaaa gatatgagct tgatcaaata aagatgattt
      601 atgtacctgc cattaggaga ccagatgaac agttaaaaaa tgtctcagga acaataattt
      661 caagattatt aaatggtata agttggtcag aacaaacaaa ggcaagaatt aaaacgaaag
      721 caagtgaaac ggaggaaatt ttctttgaag aaaaaggggt tgaatcatta aagaaatcac
      781 tcgaaactca atggaatagt tatcataagg atattagata ttctaatcca aagataaact
      841 tcaatagtac tgatttagag acaattttaa aaaaagttga agtaactttt tcacctacag
      901 ggacacatcg agattatcgg gttgaagagc ttggagatgg gttacgttct ttattttatc
      961 tttcacttgt aaatacattt ttagaaattg aagaagaaat tctaaaatct attaatgatg
     1021 gtaaagaaga agatatattt acattaatac cgcctgtatt aacaattgtt gcggttgaag
     1081 aaccagaaaa tcatatttca cctcatcttt taggaagggt agttgaaaaa ttaaatttta
     1141 tttctacaaa agaaaattca cagacaatat tgacatcaca ttcaccagca atagtaaaaa
     1201 gaattgaacc aacagacata aggtatttta ggatttgtaa ggaatatgaa tgtacaaaag
     1261 tgaagtcaat tatattacca aatgaagaaa aggaagcaga acaatttaaa tttgtaaagg
     1321 aatcagtatt agcatatcct gaactttatt ttgcaaaact tgttgtattg ggcgaaggtg
     1381 atagtgaaga gatcattatt aagcagatga ttgaattaaa agcagaatct gtagattcat
     1441 cagaaatttc aatagtacca ttaggtggta ggcatgttaa tcatttttgg cgtttattaa
     1501 atgatttaga aattccattt attactttgt tagatttaga tagagaacga gatggaggtg
     1561 gttggggacg tataaagtat gcaatacaac aattaataaa tattggtcat gataagaatg
     1621 tattacttta tacatgtgaa ggaatttcac aagataatga atttaaagag atgcatactt
     1681 gggatgtaac tgatactgaa aatatggcta aatggattga aatgctaaaa ggttatgatg
     1741 tttatttttc agctccgtta gatatagatt ttgcaatgtt acaaagtttt aaagataaat
     1801 atatttcagc attaacaagt gcggaaggtc ctaggataaa agatcatgga aaaatacaag
     1861 atattgtgat caatgaagat gctgaagatg aatcattgaa agctgcttat aaagatagaa
     1921 tagatagtga tattaaatca accttaaaac aagaaggtgg tgatggatct acttatactg
     1981 agggagagaa agaactaatg atatggtatt catatttctt tttaggaaga ggtaaaccaa
     2041 ctactcattt atctttattt tctaataata ctgatataga ttttgaaagt tttccatact
     2101 gtctaaagga gtttgtaaat agtattattg aaaagatgat agatgattca gggggtggaa
     2161 gaaaatgaag aggaattggg ttagtaaaga agattggagt ccagcggctg gattcagact
     2221 agaagttgaa gcgatgaata cagttattaa tgataagaat acacttgttg tagctggtcc
     2281 tggcgctgga aaaacagagt tattagctca gagagcctgc tttttactag agactaatac
     2341 ctgtagatat cctaaaaaaa tccttgctat tagttttaaa aaggatgctg ctgaaaattt
     2401 aaaagagcgt ttagaattga gatgtgggaa agaattagct tcaagatttg aatcaaagac
     2461 ctatgatgct tttgcaaaag aaatcgtaga tagatttaga aatagtttag atgaagcata
     2521 tagaccttta aataattaca atatagctga aaatcgtgat gttagaagag catttgagat
     2581 agcaggatta aatttcagag gaaatcaaac tgaatttaat aaagtatatg gaaataaact
     2641 atcgataaat aaattgcctt tacatacaga ttttgtagat aagattttta tagatgcttg
     2701 gaatgtacta cttaaaggca acaaagatac taattttgta agttcactta cttttggtat
     2761 gatatcacgt ttagccgaat atttgataag aaccaatagg tatattaaga aagcaattga
     2821 aatgacttat agtcatgtgt ttttagatga gtttcaagat actaaatcta ttcaatatga
     2881 tcttgttaaa gcttgttttt ttaaaacaga aacaataatt actgctgtag gggatggcaa
     2941 acaacgaatt atgttatggg ctggtgctag aaagtcaata tttgaagatt ttcaaaatga
     3001 ttttttaagt caaaaaagaa cattaattat gaatcatcgt tcagcgccaa gacttgtaga
     3061 gattcaaaaa gcaatgtata acagtttgaa tgaagaggca attgatttaa aaactaatga
     3121 aaagtggaat tatgaagatg gagaagtgta tttaagactt tttgaggatt atataaaaga
     3181 agctgatata cttagtgagg aaatagtcga attggtggaa acaggtatag aaattaatga
     3241 aatatgtata ttagtaaaac agagcgtaga tatttattca aaagagatta taaataaact
     3301 ttctgaacgt aatattaagg cgcgtaatga agcaatgtat caggagatat taaaagaaga
     3361 tataataaag acactggttt cgctttttag gttgtcgtta agtgatagaa atcccgatga
     3421 ttgggattat atttacgata ttctaggtga attatatgga atagacgaag ggtataaccc
     3481 taaaatatta aatgatttca ttaccaaagt agaattaatg attaatgatc tcaaggtaaa
     3541 tttaaatatt actgatgaaa aacaattttc agatttagtt gattctaagg ttgaatatat
     3601 ttcatatgaa aaatttgcat caaagtttca aaaatataaa tctaaagatt attttgatga
     3661 tttggtagat aaatttaaaa agctggtatg gattgaatat aatgaaacta aagattggat
     3721 taaagcgatt gataactttg aaggtaaaaa ttcaattcca ataatgacaa ttcataaaag
     3781 taaaggactt gaatatgata ctatcttttt tgttgggtta gaagattcag cattttggaa
     3841 ttttaaaaat caaccagatg aagatagatg tgcatttttt gttgcattat caagagctaa
     3901 aagaagaatt gattttacat ttagcttaga tagaccagca ggattttcga attcacagaa
     3961 gcattattgt attaatgaat tctacgaatt gtttgataat actgagattg taaaaaagat
     4021 agagtattga ttaagatgat aaaaacttta gtatattata ttttaagata ttagttatat
     4081 aagtagacat tgaatttatg tatttgatgt ctatttttta tataaaaata tattaaagaa
     4141 aggatgaatt tgcatgaaga aaaaaacaaa aatatctaaa aagattgtaa gttttattat
     4201 ggtttttata actatagtta ctactatact tacatcatca gtttcagctt atgctagcga
     4261 gttggatatg agtgaacaga caggctttaa ttatttaggt attagtccaa ttacaggaaa
     4321 aaaattaatc ataacattta tcgtatgaag atggataata aaattgtatt ttgtgtagag
     4381 ccaggaatta aaacttcaag tggaggagga tatatatcgg aggagttagg agataaattt
     4441 atatctacaa cacttccaaa ttatcataaa agaaaagctg aaatacttga gaaggtaaat
     4501 agacataata tattaccttc atggaataat gaaaaagttg cagttaaaag tggagaaaca
     4561 attgagttag aagataagaa tggtattatt agagaaatgc aattagaatc aaataatact
     4621 ggaacagata tattacttga agaaaatact ttgaaaatta cagcaaataa aaattctaat
     4681 tcaggagtta ttagttatat aaagattcct aaaaatgagg ttggaatatc aatagtttat
     4741 cgtaagcata actatcaaag cttatcagaa tttcatatgg aaagttcgat gagtgcaaat
     4801 ttaaatataa atgtaatcaa gttaggaatt gttaaagtaa aaaagattga tgaaggcaca
     4861 ggaaaggaat tagcaaatgc aaaacttaga tttgagtatg atggtgatag taaagaaatt
     4921 ataacgggtt ctaatgaaat tgctagtata gaagatatta ttggttgatt aaaaagtgaa
     4981 gtatactttt gtatctatga aaaagactat aagcaatata taaaattaga tatacctatt
     5041 gatgaagcaa aaataaaaaa tagatttgaa ataaggttaa aaaatgaaag agcatatcat
     5101 gcagcagttg atttgttagc aaatagagat gaagaaaaga cagcattttc aattattaat
     5161 cgttatatac gttttgttga taaagatgat gaaaaaatta gaagtgaatg gaaaactaat
     5221 gatcagtgga gttattttat tggtgaaggt agagcgaagt taaaactaac aacaaatcca
     5281 gaaccatata atattcaaaa aactttaaat tggttatcaa gacaagttgc accaacgtta
     5341 aaaacaatta aaaggttaga tagtttgaac aactcaacat taattgaggg cttaataagg
     5401 tatgcaagac taacagataa acataaaaaa ataattgaac aaaattcagt aaatgttgaa
     5461 gacattattt atgatgaata aaaaaatgta attagtattg cagattttaa tataaaagaa
     5521 gggagatata cgaatgaatt ttggtcaaaa tttatataat tagtttttat caaatgcaca
     5581 atcattggta ttaatggcta tagctataat tggtgtatat ttaggattta agagagagtt
     5641 ttcaaaactt ataggatttt tagtagttgc attaattgca gtagggcttg tgtttaatac
     5701 agcaggagtt aaagatatat tattggagct atttaataaa ataataggtg tgtaaggatt
     5761 aaaagagaat agaaaattat gagtatatga tgaagggttc taataagttt tattaaaata
     5821 tatattgaaa gacaagtaga gctatttcga gttattacat gtaatgctaa tatatataac
     5881 tgcattttgg aaattaaata cataattaga aatagcaaat tttataggtg acttattaat
     5941 atgtttactt attgtatact atttgatata tttaatatga ggtgattctt gaaaatggac
     6001 atagtgaaag tttttgctaa caatgtgaga aaatatagaa ataaaaaagg tctatcacaa
     6061 gaagcttttg ctgaaaaagc tggattgcat agaacttata tttgtgctat tgaaagaaaa
     6121 aagagaagta ttgctttaga taatgtgcag aaaattgctg atgcgcttga gattgagact
     6181 tacttactat ttatagaagg tgaggagaaa gaatgtctat gaaaaaatta ccaatagaaa
     6241 agcttataga aaatttaggt ttttcagggt caaagaatct tgtgaatata gatatgctta
     6301 caaaattaga tatatctaaa catgatgtaa aaactttaaa agttataaat ccttatgcaa
     6361 tttatttagt aaatagtaag ccatttatat tatttataga gtcttctttt gaagaaaaaa
     6421 aattacaaca aattagtaag cttatatgga atgctcaaat accaattgct tttatatgcg
     6481 attctaattc tgttaaaata tttaatggaa aagctttgga tttaaagtca tatttaattg
     6541 aggaaatata taatcaatct attgaggatt tttcggaaga atctgagttt tcttatttga
     6601 aaatatctga tccattattt tgggatcaat acactaaaca atataccaaa acgcatttaa
     6661 atgattattt gctagataat attacttcat tgacaaataa attaaagaaa aaatataagg
     6721 tgaaatttgc aacgaagctt gttctaagat taatatttat tagatattta atcgatagag
     6781 gtgtcgatat agcttataaa aattttaatc atgatattaa agcttcacaa aaagaactgc
     6841 taaagattac taaaaacaaa gttgaattat atgaactgtt taaatactta aaagaaaagt
     6901 ttaatggtaa tttatttgag ttaaatgacg aaattaataa tacttgttta acagatgaag
     6961 tgtttatttt actatctgat tttttatcag gtaaaataag tattgacaat ggacaaatgt
     7021 ctttattttc aatgtatgac tttaatatca taccagttga actaattagt aatatatacg
     7081 aaattctttt aggaaaagaa attcgtaata aagataacgc attctatact ccgaattact
     7141 tagcagaata tattttagat aaaacaacac ttgaatttct gaaaaataat aggcaataca
     7201 aaattctaga tccttcttgt ggatcaggag tatttttagt aaatagtttt agacgtatta
     7261 ttgatatgaa tttgggtgat aaactttttt gtgaagatga taaactttta aaagaacttt
     7321 tattatctaa tatttatgga attgatatca atgaagatgc tatcgatgtt actattttct
     7381 cgttatatct aactatttta gattacaaag accctaagat attatcagaa tttaaactgc
     7441 ctaatttaaa agggtgtaat ttaatagcga gtgatttttt tgatgataat aaattggaga
     7501 gtttaaagaa aattaacttt gattttatca ttggaaatcc gccttgggga agtgtctcag
     7561 atggattaca tttagattat tgcaataaaa atggctataa tgatatgcaa caaaacaaag
     7621 aaatcagtag aagttttatt tttagagcaa aagattttag ctctagaaat acagtatgtt
     7681 cttttgtagt gcattctaaa atactatata ctcaaaaaaa gccatcaaaa aaattccgtg
     7741 aatttttgct taaaaaaagt caaatattta gtgtagttga aatgtcatct gtaagaaaat
     7801 tagtgtttaa aaatgcagac gctcctgcag cagttatatc atttaagtat aacgaaagtg
     7861 aagaaaattt aaataataga atcatctata catctttaaa accaaatgta ttttttaaat
     7921 tatttaacat tattgtaatt gaaaaatatg atgttaaata tatttcacaa aaactattat
     7981 tggagaatga ttgggcttgg aaaactattg tgtatggatt cagtaaagat atagatataa
     8041 ttatgaatat caaaaaaaaa tatcaaactg taaatgaaat tattttgaaa aacagttttg
     8101 ttcatggaac agggatacaa atcaatggta atgaaagcca tgatgcgaca catttaaaag
     8161 gaaagtggta tgttgattca aagaaaggaa tagattcatt ctatgttgat ataaataaag
     8221 ggaaagaact tactcaagat aaaatgagaa gacctaaggc taatcagcaa gaaatattta
     8281 ttcctccata tgtattatta aaaaagggag ttgacacgaa aacatataga tatagagcag
     8341 cattttcaaa tgatgcattt gtatattcag atgcagttac aggaatatgt ggaaaaaaag
     8401 ataatttaac tacactttat tgcttgactg gtatgcttaa ctcttctttt tactcatact
     8461 taaatataat gctaggtaca tcaattggaa tagaaagaga acaaggattt tcaacggaaa
     8521 tttttacgta tccagcaata gaaagtgatg aaattgctaa tctggtagta aaaatacaag
     8581 aagcgactaa attagaaaaa acaactatgt tcttgaatga aaaaaatagt tgtaagtata
     8641 tcaaacaatt agataagtta attttgaagt cttttaattt aaatgatgat aaatttattg
     8701 actatgcaat aaatattcaa attcctgagc ttacaaattc taagtcaact aacatatata
     8761 gaaaaataac taaggaagat ttaattaatt atagtgaatg tttcaaagaa cagttttcat
     8821 cgatatatcg tagggttggg aaaagtattt caatttcggt atatccaaaa atattaaatc
     8881 gttttacagt atttgaacta gaagtaacag atgaaaaaac agatagagag attatggtta
     8941 aagcagaagc tgataataat atggagttgt ttacgaaaat aattagatat gattataatg
     9001 atgtttttca tcaaattaga gatattattc attttggaga aaattcattt tatatcataa
     9061 agcctaattg ctataaatat tggcatcctg ctatcgcaga aatggatctt gctgatgttt
     9121 tggatcagat tttatctgat acagggggtg aagaataatg ggaggattta aaaattcttc
     9181 actaaacttt tatttaaagc aagggcttta tgaaataatt atagatggat taatagactg
     9241 ttgtttactt atgagcaaat catgtattga acaatctaga aaaatattaa atcacgaaga
     9301 aaagataaga acgcatttag ttgaaaatta tttagaaaat gatattgaaa gaagaaaaac
     9361 atctttatct aaacaacatc taagatttga agtagaagca caagaaaatt atgacaacaa
     9421 aaatgaatct tatgagggta gggttgatat aaaagttata tctaaagaca ctttagcgga
     9481 tagaagggct tattatatca ttgaatgtaa aaggatagat ggtaaggaaa ctttaaataa
     9541 aaaatatata accgaaggtg tacaacgatt tattactgag aaatattctt cgcattatgg
     9601 caaaaatata atgcttggat ttatagtaaa agatataaat atccagagca atatacaaaa
     9661 aattaattca ctgaatcaga acatattata tacatatata gatacagata tgttgacagt
     9721 tagaagtgat tctgaaaata attatgctgt ttgtgaaagt aaatataaag taaaatctaa
     9781 actactattg ttaaatcata ttttttataa cttttcgagt ataataagat aatcttatga
     9841 atataaaata ttactatgtt aaaattatag tttggttttg ataatattat aaaaataagt
     9901 ttaagaataa aatataaagg aaaaaagggg cgtagcacta ttttttagtg tgacagcccc
     9961 tttaatttta aaatcggtaa ggaggagtgt atttgaaaaa aattaagtca tatacaggga
    10021 ttttgaatgt ggagaaggtt atatatgcaa taaatgattt tcagcttcca tttccagtta
    10081 cttttacgca gatgacatgg tttgtattaa cactttttat aattatatta tttggtaagt
    10141 tacctccatt atttatgata gaaggagcat ttttaaagta tcttggcata ccaattttta
    10201 taacttagtt tatgtctcaa aagacttttg atggaaagaa accatatgga tttttaaagt
    10261 caataatact atattcatta agacctaaaa taacatacgc aggaaaaaac attaaattta
    10321 aaaataaaat tattgatgaa aatataacta tagtaaggag tgaattatat gttcccgata
    10381 aaatatatag agaacaatct tgtatttaat aaggaaggag aatgttttgc atattatgaa
    10441 ttaataccat ataattattc attcttataa gctgaacaaa aatttattgt acatgataat
    10501 tttaggcaat taatatcaca aagtagaaat ggtaaaattc atgcacttca aatagccact
    10561 gaaagttcta taagagttac acaagaaagg ttaaagaaaa atattacagg aaaattaaaa
    10621 gaaattgctt atgaaaaaat agacgagcaa acagaggcac ttgtttctat gattggcgat
    10681 aatcaaattg attatcgttt ttttattggg tttaagcttt tagttacaga gaaagaaatg
    10741 aatataaaga gtataaaaaa gtcaatatta gctaatctat cagattttat atatgatgtt
    10801 aataataaat tgatggatga ctttgtcagt ataaataatg atgaaattat gagattttta
    10861 aaaatggaaa agttattaga aaataaaatc tcaagaagat ttaaagttag aaggttagat
    10921 aaaaatgatt ttggatattt aattgaacat aattatggaa agaaaggcac agtttttgaa
    10981 gattatcaat accatttacc tacaaagaaa cttaaaagag aaacattagt aaagaaatac
    11041 aatcttataa agccaactag atgtcttata gaagagaagc aaagatactt aaaaattata
    11101 catgaggatt cagaaagttt tgtagcttat tttactattg aaattattat tggagaaatg
    11161 aattttccat ctagtgagat attctattat cagcaacaac agtttgcatt tcctattgat
    11221 actagtatga atgtggaaat tgtaacaaat aaaaaggctt taactacagt tagaaataag
    11281 aaaaaagaat taaaagattt agacaatcat gcttggcagt cagggaatga aacagtaaca
    11341 aatgtagtag aagcattaga ggctgtaaat gagcttgtaa ataatttaaa tcaaacaaaa
    11401 gaatcaatgt ataagttaag ctatgtaatt agggtatcag cagatagcat tgatgaatta
    11461 aaacgccgtt gtgatgaagt taaagatttt tatgacgatt taaatataaa attagtacgc
    11521 ctaatgggag atatgatagg atttcacaat gaatttatac cttcaagcaa aaggtatata
    11581 aatgattata ttcaatatgt aactagtgat tttctagcag gattagggtt tggagcaact
    11641 caatagcttg gagagaacga aggaatatat attggatata gtttagatac aggaagaaat
    11701 gtctatcttc aaccatctct tgcaagtcaa ggagtaaaag aatctgtaac taatgcgttg
    11761 gtagcagcat tctttggatt tttaggaggt gggaaatcat ttgctaataa cttacttgtt
    11821 tactattcag tattgtttgg agggcaagct gttttggtgg atccaaaagc tgaacgtggc
    11881 aaatggaaag aaaatttacc agatatatat catgaagtaa atattgttaa tttaacaagt
    11941 gatatagaaa ataagggaat gctagatcct tatgtaatta tgaaagaagt aaaagatagt
    12001 ggaagtctag ctattgatat attaactttt cttacaggaa taagtagtca tgatggagag
    12061 cagtttccta tacttagaaa atcaatcata aatgttactc aagacaaatg cagaggactt
    12121 ttgaaggtaa tagatgaatt aaggaaagat aattctcaaa tatcaaataa tattgcagat
    12181 catattgaaa gttttacaga ttatgatttt gcacaattac ttttctcaga tggaaatatt
    12241 aaaggctcaa ttaatctaga aaaacaaatg aatataatac aagttgcaga tcttgtttta
    12301 ccgaataaag atactttatt tgaagaatat acaacaatgg aaagtctttc agtagctatg
    12361 ttgatagtaa ttagtacttt tgcattagat tttatccata cagatagaag tacttttaaa
    12421 atagtagatt tagatgaagc ttggacattt cttaatgtag cacaaggaaa aactttatct
    12481 aataaattag ttagagcagg atgtgctatg aatgcaggag tgtattttgt aactcaaaat
    12541 gcaggtgatg tatcagatga aaatttaaaa aacaatattg gattaaaatt tgcattcaga
    12601 agcacagata tcaatgaaat taagagaata cttgaatttt ttggagttga taaggaagat
    12661 gagaataatc aaaaaaggtt aagagagtta gagaatggac agtgtttaat acaagattta
    12721 tatggacgag ttggggtaat acaaatacat ctagtttttc aagaactcct tactgcattt
    12781 gatacaagac cacctataag aaaagaggtg gattaatgaa atcgaaagta tttagaaatt
    12841 taagctggat aactatttta atagtagtac ttttactatt ttttatttat ataaatttat
    12901 agatttagag aaacaaatag atacattaga taagaaaaga aaaaaactca tagatatgag
    12961 attagaagat ataattgata aagaatcata tgaagaaaag tatgatgatt taacagttga
    13021 aataaagaaa cttagtaaag agaaaaaaac tcttaaagca tcattaataa atgaaaagag
    13081 tataaaagca agacttagag aatttagaaa gatacttgaa agaaatgaat tgttagaaaa
    13141 atttgataga tatgtatttg caagtatagt agataaggtt atagttggag ttattaatga
    13201 agatggtata gttgatcctt ataaaataac ttttgtttat aaaactagct ttgatgataa
    13261 acaagatgga cataaattta taaataagag tccgttagaa acgtattcaa aagataacaa
    13321 cgataataaa aagaagtgtt catatactaa taatgagaca ttgcgagact gtagttaaac
    13381 ttattagaga ataacaaggt ttcagacttt tatattgtgt cttaaaagta gatttgccac
    13441 ctatttgcca ccataattat ttttgggtgg caaatttatt ctacaatgat ttcaaaaata
    13501 tttaccgtct ggtttctcat gttgttagtt acatgtaaat atgtatccat agttgttgaa
    13561 gttttagcat gtccgagtat atgctggata tcttttatat tagtaccatt ttctaataac
    13621 atagtatcag ggtttttaaa ataaagtgtg tattcttcta aagtagtgat aattaaaata
    13681 tcaaatatca ctatacaaag gaaagtgcac gctttttatg tttaacaaaa acgaaatatt
    13741 aaaaaactta ttgaagaata tgatgtcaaa acaactacag atattcaaga tatgctaaaa
    13801 gatttattta caaatacaat tcatcaaata tttacattgt cgaattttag cggtttaaac
    13861 ataatatatt gactgatata ataaaatcat agaatatttt agggggaaat agattatgtt
    13921 taagaaaaag ttaatagctg ttgcaatgag tataactatg attagtgtag ggagcttttc
    13981 gtatgctcat tcaggaagaa ctgattcatc aggaggtcat cgtgataata aaaataaatc
    14041 tggattagga agttatcact atcattgtgg tggttatcca gctcatttac ataataatgg
    14101 tggttgtcct tatactggag gaggaagcag ttctggaaca acaacttcgg ttaataatga
    14161 agaaaagcaa aagaggtctg ttggagaaaa aggatataat caagggtatg aagatgggta
    14221 taaaggaaat tatagttcat caaattatag tggagattat agtgatacat atgaatcaaa
    14281 gtactcagaa ggatatgaaa aaggtaaggc taaattagaa gaggaagaaa aggtggctaa
    14341 agagactgga tataatttag ggcttacagg tgctaaatct aataatacat atgaaaaaga
    14401 agttttaaaa aatgcttatg ataccggata ttcaactgga tacaatgaat ataagactaa
    14461 aaagatagaa gaatataaag ctaaagggat agaggatagc aataaagata aggaaaaaat
    14521 gacatttgaa gaaaacatag attctgaatt tatagatgct tataataatg cttatgacga
    14581 aatacaagaa caattaaaaa atgattacac tactcaagga tttgagagtg ctatcaaagg
    14641 agaaagattt gacacatcaa ctataggtaa tgttaaatat gctaattggt ttaaagaagg
    14701 atatgataat ggtaaggtta agttacctaa agcaaaagaa agtgtatata atcaaggtta
    14761 caatgaagaa gattttagta taccagatga aatgaagtct attgaaacta agttaaaagg
    14821 tgtatatgat gaaggtttag aaaaaagaga agaagagaaa agtagaaatg ctacttatgg
    14881 ggttggagct ggaacagcag ctgtagttgc tggagtagta tataagaaga aaaaacgtaa
    14941 aaagatatag atgctagata taccaatgat gacaagtgta taacaaatat aattttaagt
    15001 ataaatattt aaaatataga agggaaggtt atatctatgg gatttaactt taggaaaagc
    15061 ataaatctag gaggaggact caaattaaat ttaggtaaga agagtgtagg tataagtgct
    15121 ggtgttaaag gtgctagagt gtcagttaat tcaaaaggaa gaaaatcagc tacattgagt
    15181 atacctggaa ctggaatatc atatacaaaa actagtacaa agaaacgtaa acctaaataa
    15241 atatttgata tactaagaaa tagactgtta caaatagtct attttttagt atatagattt
    15301 aaaaagtgac aaaattttga aatataaact aatttcataa aggaaaatat tattttatgt
    15361 agaattataa tatttaagta atattataaa atttatagga ggatttcatt atgaaattaa
    15421 gcaaaatact attggcaata gggatgtctg tttcattatt gattgctagt tgtccaacat
    15481 caaacgctct tagttctatt aattcaataa aaggtacaaa taagtatgaa acagcaggtt
    15541 taatagcaga taaacaaaat tatgatattg caatacttat taattctgaa aatggattat
    15601 ctgatggatt gtcagcaagt ggattgtcag gagctaaaaa tgccccaata ttgttaacta
    15661 agaaagatac aatcccttca gaaacattaa aaagattaga aaaggtaaaa gaagtatatc
    15721 taattggagg aaaaaattcg ataggagcat cagttcagaa aatattaagt gataaaaaaa
    15781 taagcataaa tagaataagt ggaactgata gaatagatac aagtcataaa gttgcaaaag
    15841 aaataggaag agtaagtacg gttaaaaaag taatattaac taatgctttt aaaggcgaac
    15901 cagatgctat gagtgttgct tctatagcag ttagagataa atctccaata gtattaactg
    15961 atggaaatac tacaagtttt gctacagatg gattagaaac ttatgcaatt ggtggaaaag
    16021 tcagtatgag tgataagtta ataaatgaaa ctaaagcaac aagaataggt ggagtagata
    16081 gatacgatac aaataaacaa ataataaata aattttataa tggctcaaaa gaattttaca
    16141 tagcaagtgg gactgattta gtttattctt tagttggttc tacaattgca caaaaaacac
    16201 ctatagtgtt agttggaaat ggaagtaata agagtatatt aaaaaatgca agtaaaataa
    16261 ctgctattgg aaatattgat gatgttgtta taaaacaatg tttaaatata actaataatg
    16321 ttggggattc aaatacaggt attgtaaaag atactaattc aaataatacg aacaaaccaa
    16381 gtaatgagcc tagctctaat aatcctggat taactgataa aagtacagta tatgtaactc
    16441 ctaatggaaa atcatatcat ctaacaaaaa attgttctac actaaaaaga agtaaaacaa
    16501 taaataaagt aacattaaaa caagctaagt cacaaggtaa aatagatcct tgtaatgttt
    16561 gtgtaaaata atgtattagc caaatatata ttaaaaaaga caattaatta agattgtctt
    16621 ttttattgaa gaaatataaa tttatattat gtattattaa aaaaaaatta ttaattataa
    16681 aaaataataa taaagacgat aagtattaaa attttatgtt tccaatattt atgatataat
    16741 taatatggca aggaataaat atttgaaaaa gctatgagtg gtgtttccat ggaagtttct
    16801 tcactttctt atgagaggag gtgaaaacta tggaaaatct aatgatgagt attataactg
    16861 gtgttatagc cagttacatt tacgataaat taaagagcca ctctgagcga ccaactaaga
    16921 gtggctggga acttaatata aagttccaga aaagtaaatc ttcaaaataa tttgttgaag
    16981 gaaacatcac tcaaagttaa gtaaaatatg tttccttgct tttattatat cacaaattaa
    17041 aaatattaac acaaaatttt gtgaatatat acttattatt gttctaaaaa aatatgtaaa
    17101 taattgattt gattgcatgg aattattgat gtaatattta agttaaatat acacaatctc
    17161 aattaaagaa gataagtact ataaattcat atcaaaaaaa tacataaact tttaagttat
    17221 aattttataa aaagtctttt agtatcatta tttcaagagg aattatcata tgaaaaaata
    17281 acttcattag aaaagtggat aaaaaactgg taagaaga
//
LOCUS       DAYAOO010000088        17087 bp    DNA     linear   BCT 12-OCT-2024
DEFINITION  TPA_asm: Clostridioides difficile isolate ST8-SSI-h139-18
            SAMN40601845-rid21577343.denovo.089, whole genome shotgun sequence.
ACCESSION   DAYAOO010000088 DAYAOO010000000
VERSION     DAYAOO010000088.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN40601845
            Sequence Read Archive: SRR28438827
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 17087)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 17087)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-MAY-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-MAY-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002157583.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002157583.1
            Genome Coverage       :: 163x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/11/2024 16:19:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 4,038
            CDSs (total)                      :: 3,963
            Genes (coding)                    :: 3,930
            CDSs (with protein)               :: 3,930
            Genes (RNA)                       :: 75
            rRNAs                             :: 6, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 60
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 33
            CDSs (without protein)            :: 33
            Pseudo Genes (ambiguous residues) :: 0 of 33
            Pseudo Genes (frameshifted)       :: 7 of 33
            Pseudo Genes (incomplete)         :: 25 of 33
            Pseudo Genes (internal stop)      :: 11 of 33
            Pseudo Genes (multiple problems)  :: 8 of 33
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..17087
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN40601845-rid21577343.denovo.089"
                     /isolate="ST8-SSI-h139-18"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Denmark"
                     /collection_date="2018"
                     /collected_by="Statens Serum Institute"
     gene            497..1309
                     /gene="modA"
                     /locus_tag="ACGI5H_003125"
     CDS             497..1309
                     /gene="modA"
                     /locus_tag="ACGI5H_003125"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423147.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0030288 - outer membrane-bounded
                     periplasmic space [Evidence IEA];
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0015412 - ABC-type molybdate transporter
                     activity [Evidence IEA];
                     GO_function: GO:0030973 - molybdate ion binding [Evidence
                     IEA];
                     GO_process: GO:0015689 - molybdate ion transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="molybdate ABC transporter substrate-binding
                     protein"
                     /protein_id="HFG9698817.1"
                     /translation="MFKKLSVLALAMIISLSITACNSKENKANDESNTKVTTADDSKE
                     KETLFVYSGAGLKKPMDEIAKKFEKENNVKVEYSYAGSAQLIAQIETSHKGDVFIVGS
                     EPIYSKAFEKELVGEHKTVAHHTPAIVVPKGNPANIQKLEDLNKDGVKLILGDKESNA
                     IGKTTQKILEKNNLKSINDNVVSTAATVNEMIVQLTSSKADATIATKDSVFGNEDVEV
                     IEIAQDKNIDQLISAGIVNYSDKKDLANKFINYIESDEAKQIFKKYGFEPVK"
     gene            1319..2110
                     /locus_tag="ACGI5H_003126"
     CDS             1319..2110
                     /locus_tag="ACGI5H_003126"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861521.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HFG9698818.1"
                     /translation="MKNKFFTTLLTGFFAIVFLFIVSPLLMLIIKGISYVPICLKSVE
                     VQYAIILSIKTSLISTIVCLLLAIPVAYFLHITKLPFKKLIIQIINLPMSLPHLVSGI
                     ALLLLFGRMGIGDSIYKIFKLDFIFTKQGIVLAQVFVNLPLTIKILYTSLNESNEKMI
                     FVARTLGCNSWEAFRFIILPNLKTGIISATVMTWSRALGEFGAVAMIAGSTRMKTEII
                     PTSIYLNMSTGDIDIAIGIAVILIFISLTCLMLFEIFFNREVDKN"
     gene            2112..2807
                     /locus_tag="ACGI5H_003127"
     CDS             2112..2807
                     /locus_tag="ACGI5H_003127"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893573.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HFG9698819.1"
                     /translation="MLKIKNLSLDLPNFKLQENSLNINNHEYFVLLGASGSGKTLFLE
                     TLAGRYPSAKGNVSYKENLISNLPPENRNIGFVYQNFELFPNMNVEDNIRFPLKLRKI
                     PIDEQILKANHLSKLMQIEDIKNRYPKNLSGGEKQRVAFARALIAEPDILLLDEPMSS
                     LDYITKKHISKILKDVYIKYKPTVIHVTHDISEAMFFAHKIGIMNNGKINHIFDLNEE
                     IKNKGESFFYEYI"
     gene            2794..3525
                     /locus_tag="ACGI5H_003128"
     CDS             2794..3525
                     /locus_tag="ACGI5H_003128"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423141.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF364 domain-containing protein"
                     /protein_id="HFG9698820.1"
                     /translation="MNIFDILRDYLLVQVDKYNLNMDMISIVSKSLSSKEAIGNTKRK
                     DFPIIVGKEIMLEADFKGAKGQAFTSTPSTFEGSLKDILSLDLHDNPHDRSLFIASLN
                     AVMKYLGKTDRTIHCKNNEPEICAKKFPEFIKMEFGNPKVAIIGYQPAIIDNIKDFFE
                     TRVLDLNPEFVDTIQYNVKIEDGIRDYEDVISWADLVICTGSTLCNNSIINFLSLNKP
                     VYYYGTTIAGASNILGLKRLCFCSK"
     gene            3839..4639
                     /locus_tag="ACGI5H_003129"
     CDS             3839..4639
                     /locus_tag="ACGI5H_003129"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423139.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PIG-L family deacetylase"
                     /protein_id="HFG9698821.1"
                     /translation="MTFKNKKFTINKYKILSIILVLCLILTAFSSYVNYSHKKFKDYV
                     VFYVQHQDDEVLWAGSAIVNAIKERGKNHVFVVLVSTGCGISVFDKYKKYENLTNIQK
                     SEYRNREFLASLNSLGVIRENIILLPETNTNGNTDFNYMEKIALTFEEKFKNVTHIAH
                     TYKLDDHLQHLKNGSVIQNLYNAGKIKDAKYFVKPKFADKITFNNKIVYKAHSTEDYE
                     KVKNACQQYKIVDELEYREGIGYKSDHKSFDKLLNNKDVPAILHTPNL"
     gene            5179..5895
                     /locus_tag="ACGI5H_003130"
     CDS             5179..5895
                     /locus_tag="ACGI5H_003130"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890517.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000156 - phosphorelay response regulator
                     activity [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HFG9698822.1"
                     /translation="MNQNILVVDDDREIVDAIEFYLRPDNFNVLKAYDGLEALDILIE
                     NDIKLIIMDVMMPNLDGLKTTLKIREKRNIPIILLSAKSEDMDKIIGLNMGADDYITK
                     PFNPLELTARVKSQLRRYINLGDFSNTNNSNDTNYILKSGGLELNTDTKIVSLDGEEI
                     KMTPLEYKILTLLMSRKGKIFSSHEIYENVWNEDAYSCERTIAVHIRRIREKIEINPK
                     EPKYLKVVWGIGYKIEKLNY"
     gene            5864..7456
                     /locus_tag="ACGI5H_003131"
     CDS             5864..7456
                     /locus_tag="ACGI5H_003131"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897499.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000155 - phosphorelay sensor kinase
                     activity [Evidence IEA];
                     GO_process: GO:0007165 - signal transduction [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="histidine kinase dimerization/phospho-acceptor
                     domain-containing protein"
                     /protein_id="HFG9698823.1"
                     /translation="MVTKLKNLIINDSKAKFILLLLLFLLVSILFEAVYDLNNNFSYN
                     INYYYKEFALPYFYFFGTPVHLSKVELEFVCIGIILSSFLLTILCFTLYKKNKQTKVK
                     FLENVISLFSKVKIELTLILTLILLTLRFHAFTSNKMFYNTNLIIYNFIIISIVYIIY
                     ENIKYNNYNLKDMSITYVFFSNLLNMYNKKTINKKLAIVFLISIVVQAIIQYLVLIFF
                     MYIYYAEAIAIVILFTLVNTVFHFYIYNFLSVKFNYINNISKNIKNIENGNLKYKLEV
                     IGDDEISTLAKSINNITGGLETAVDANIKNERMKAELITNVSHDLKTPLTSILSYVDM
                     LKNNDFDRETINDYINILDKKSQRLKLLIDDIFEASKLSSGDVEFNITKTDIRELLIQ
                     SIVEFEDKIQNSSLDFIIETPEYAVFTMIDGKKTWRVFENLICNILKYSMPNTRVYID
                     MFIKEENIILTFKNISNDKLNLKPEELIERFRRGDISRKTDGSGLGLSIAQNIIELEN
                     AHMEIIIDADLFKVMLTFRRVN"
     gene            complement(7768..9270)
                     /locus_tag="ACGI5H_003132"
     CDS             complement(7768..9270)
                     /locus_tag="ACGI5H_003132"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890519.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphomannomutase/phosphoglucomutase"
                     /protein_id="HFG9698824.1"
                     /translation="MGDLYKLQNGTDIRGIAYENDSKEVNLTVEEVKKIAKAFHIWLK
                     EKTKKDKVTVAIGTDSRITGSQFRSTVIETLTNDDCNVIDCEIATTPAMFMTTIMDGY
                     NSDGAIMITASHLPYYYNGLKFFTESGGLEKTDIKEMLDIAVKNDSVDYEEVNKKGEV
                     IVKNLIEDYSNLLIDKIRKGVNSSKNYEKPFSGLKILVDAGNGAGGFFAEKVLHILGA
                     DTTGSQFLNPDGMFPNHIPNPENKEAMESICKAVLDNKSDLGIIFDTDVDRAAIVGKN
                     GKPINKNALIAVISSIVLEEHPKTAIVTDSITSEGLAKFINELQGRHHRFKRGYKNVI
                     NEAIRLNSEGEECHLAIETSGHAALKENYFLDDGAYLIAKILIKVAKLSLEGKTIEEL
                     IENLEEAQEEKEVRIGINKEDFRPYAEDILKDLDSHVKSIDGWSVAPNNFEGIRVNCD
                     ESNGDGWFLLRISLHEPLLALNIESNKIGGAEQIYSKLKLFLEKYDLKGL"
     gene            complement(9380..10045)
                     /locus_tag="ACGI5H_003133"
     CDS             complement(9380..10045)
                     /locus_tag="ACGI5H_003133"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728811.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004750 - D-ribulose-phosphate 3-epimerase
                     activity [Evidence IEA];
                     GO_function: GO:0016857 - racemase and epimerase activity,
                     acting on carbohydrates and derivatives [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA];
                     GO_process: GO:0006098 - pentose-phosphate shunt [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribulose-phosphate 3-epimerase"
                     /protein_id="HFG9698825.1"
                     /translation="MSIICASIMCADQMKLKEELEALEEAGVKLLHCDVMDGIFVKNL
                     AMGPELLKSISENTTIPLDIHLATETPDKYIDMMSYIKPKYISFHVESSTNVKADIQK
                     LRNYGIGPVLAISPQTSVDKIEEYISLVEGILVMTVNPGFAGQKFNLSVLDKLDKLTE
                     ILKDYDNPPFIEVDGNINKDTIKLMNGKKVDIYVVGTSALFNDKPPISYKDKIEELKE
                     SIK"
     gene            complement(10075..10521)
                     /gene="rpiB"
                     /locus_tag="ACGI5H_003134"
     CDS             complement(10075..10521)
                     /gene="rpiB"
                     /locus_tag="ACGI5H_003134"
                     /EC_number="5.3.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430700.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004751 - ribose-5-phosphate isomerase
                     activity [Evidence IEA];
                     GO_process: GO:0009052 - pentose-phosphate shunt,
                     non-oxidative branch [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribose 5-phosphate isomerase B"
                     /protein_id="HFG9698826.1"
                     /translation="MKISIGCDHGGYELKEYIKENLINKGIEVEDVGTNSKESVDFPI
                     YAKKVSQNVQSKKSDLGILCCGTGIGMSIAANKFKGIRAAVVSDCFSAKATREHNNTN
                     VLCLGERVIGKGLAMRIVEEWLNSSYNGERHARRLQMIDDIEKENL"
     gene            complement(10696..11616)
                     /locus_tag="ACGI5H_003135"
     CDS             complement(10696..11616)
                     /locus_tag="ACGI5H_003135"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430702.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transketolase family protein"
                     /protein_id="HFG9698827.1"
                     /translation="MGIATREAYGQVLKELAENKDIVVLDADLGKATKSISFKEVAPD
                     RFFDMGIAEGDMIGTAAGLATCGKIPFASTFAIFAAGRGYEQIRNSVAYPNLNVKIAA
                     THAGVTVGEDGGSHQAIEDISLMRGIPNMVVLNPADALEARQAILTSIDYNGPVYIRL
                     GRAATPDVNSENYKFEIGKGTVLREGSDITVIATGIMVAKALEAAEELAKEGINVEVV
                     NISTIKPLDEALIKETAKKTGKVVTAEEHSIIGGLGSAVCEALAETKDVVVRRIGVKD
                     VFGQSGTPADLLKHYGLTTEDIVKNIKELL"
     gene            complement(11619..12431)
                     /locus_tag="ACGI5H_003136"
     CDS             complement(11619..12431)
                     /locus_tag="ACGI5H_003136"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423126.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transketolase"
                     /protein_id="HFG9698828.1"
                     /translation="MSTLRDHSNNIRKNIIKMVAEAKSGHPGGSLSIADMLTVLYFDK
                     MNVCAENPKMADRDRFVLSKGHAAPALYATLAEKGFFPEEELITLRKFGSKLQGHPDM
                     KKVAGIDMSTGSLGQGLSAANGMALAGKLDNKDYTVYTILGDGEIQEGQIWEAAMTAS
                     HYKLDNLIAFVDLNGLQIDGSNEEVMNVSPVDDKFKSFGWNVIVINGHSFEEIGNAVD
                     EAKKVTGKPTVIIAKTVKGKGVSFMENNAAWHGTAPNAEQAEQALKDLEGGL"
     gene            complement(12523..13554)
                     /locus_tag="ACGI5H_003137"
     CDS             complement(12523..13554)
                     /locus_tag="ACGI5H_003137"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861524.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc-binding dehydrogenase"
                     /protein_id="HFG9698829.1"
                     /translation="MKAVVKTKPGYDNVEVLEVEEPKATGDKVKIKVEYSGICGSDIH
                     SFKGEYANIKAPVTLGHEFSGIVVEVGEDVKNIKVGDRVTSETTFATCEKCIYCETKD
                     YNLCPTRKGIGTQVNGSFAEYVLSREESIHVLPENVSLLSAALTEPLACCVHAALEKT
                     TIESSDTVLIIGPGPIGLLLAQVVKSQGATVIMSGVTKDKERLEIAKNLGVDRTVNVM
                     EESLADVVNEMTDGNGVNKGFDCSGFMPAVNEALRLLRKKGTFVQVGIFAKKLNEMDQ
                     EAIIQRELQYIGSRSQKPSSWITALDLMANGKVNTEALVTRTVGLDEFKEGITALMNG
                     EEIKVAVKS"
     gene            complement(13554..14606)
                     /locus_tag="ACGI5H_003138"
     CDS             complement(13554..14606)
                     /locus_tag="ACGI5H_003138"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430708.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactitol-1-phosphate 5-dehydrogenase"
                     /protein_id="HFG9698830.1"
                     /translation="MKAAVLHGTNDMRFEDIEIKPCESDEVKIKVMAAGICGSDPPRV
                     LKHWKYPVPAIPGHEFSGVIAEVGKDVKNVKVGDRVVAIPFIPCNECEYCKRGLFSLC
                     DDHGMLGAKSFGAFAEYVNIKATNVLPIGDMNFEDAAMIEPLAVAMHGVLNIGVQVGD
                     TVAVMGSGTMGQLVIQGLKIAGAGTIIAVDISDNKLRESKELGADIIINAKDINPVEK
                     IKELTGGKGVDIALECAGSKITQEQCLLITKKKSKIGFLGIAYSDITLSEEAFENIFR
                     KELELKGFWNSYSAPFPGQEWTKGINLVNEGKIKLKEMVSHRFSLEDTYKAFEMIRDR
                     KEEFNKILILPQGVEK"
     gene            complement(14736..16010)
                     /locus_tag="ACGI5H_003139"
     CDS             complement(14736..16010)
                     /locus_tag="ACGI5H_003139"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002843259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS galactitol transporter subunit IIC"
                     /protein_id="HFG9698831.1"
                     /translation="MDKLLAVVQYILNMGPTVILPITIVVLGMIFRIKFTKALKSGLT
                     IGIGFVGINLVVNLLTSTLGPAAQGMVERFGLNLTVIDVGWPTTASATWASPVAPILI
                     PVCLLVNLLLLYFNKTKILNVDIWNYWHFIVAGAVGYIVTGSYVWAIFCAILMELLVL
                     FIAEKTAKNVQEFYDLEGIALPTGSTASFAPLGYLVGKFVEKIPGINKIQADPDSIQK
                     RFGIFGEPMMMGIILGIILGALAGYDVAGIFNVGISMGAVMLLMPRMVRILMEGLIPI
                     SESIRDFLQAKYGDRELYIGLDAAVATGHPAVISTALILVPITLFLAVILPGNKVLPF
                     GDLATIPFYMAFIVCFRKGNIVQSVITGTIVIAISLYMATNFADVHTQLLQQANMMPE
                     GTTMVTSIDTGGNLLKWGILKLSQLVSSFGIF"
     gene            complement(16069..16344)
                     /locus_tag="ACGI5H_003140"
     CDS             complement(16069..16344)
                     /locus_tag="ACGI5H_003140"
                     /EC_number="2.7.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423118.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HFG9698832.1"
                     /translation="MKKILVACGAGIATSTVVCDKVERLVKENNIQAEVIQCKIAECA
                     TKQEGADLIVSTTILPTTYNIPAIKATAYITGVNTAALDKKILDALK"
     gene            complement(16405..16863)
                     /locus_tag="ACGI5H_003141"
     CDS             complement(16405..16863)
                     /locus_tag="ACGI5H_003141"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861526.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:1902495 - transmembrane transporter
                     complex [Evidence IEA];
                     GO_function: GO:0016301 - kinase activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA];
                     GO_process: GO:0016310 - phosphorylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HFG9698833.1"
                     /translation="MEFINFVSDKVIDLKMDCKTKEDFFKEIHNKVFDLGFVKEEFGE
                     KILARENVFPTGLNLGDYGVAIPHTDAEYIKEQFISVCTFNEPVVFSSMEDQDEKVPV
                     NLAFVLGLNQPHSQLSVLTELMGIMQNKELVDKLMSSTDKEEVLKTLKSL"
BASE COUNT         5772 a         2733 c         2080 g         6502 t
ORIGIN      
        1 acaaaaatat atttataaag tatgtactta aacctacaag tactctttta attaaatata
       61 tagtaatata ataattttag ttgtggcaca tcaaaatttt caactatctc ataaatacat
      121 actctttctt ttgtattcaa ttctgatata acatttttag taatttgtta ataaaaagca
      181 attaaaacat atctatatgt ttcaatgttc tattttttca ctgaaatata ataaatataa
      241 aattagttaa aaagtaaaaa atctacaata agttaatttg atttaagttt ttaaatttaa
      301 aatactttaa agtattaata aaaattaaaa ataaaataac tacctataga aataacatta
      361 taaatagatt ttttcttaac tatacataac aaaacataac aaaacattat aaaacataac
      421 aaaaacttag acatcgtttt cttagtatga tatactaaaa aagaatttac attaatttac
      481 taagggggaa tatcttatgt ttaaaaaact ttcagtacta gctttagcta tgattatttc
      541 attaagtatt actgcatgta attctaaaga aaacaaagct aatgatgaat ctaatactaa
      601 agtgacaaca gctgatgatt caaaagaaaa agagactctt tttgtctatt caggggcagg
      661 tttaaagaaa ccaatggatg aaatagcaaa aaaatttgag aaagaaaata atgtcaaagt
      721 tgaatatagc tatgcaggtt ctgcacagct aatagctcaa attgagacaa gtcacaaagg
      781 ggacgtattt attgttggtt ctgaaccaat ttattcaaaa gcctttgaaa aagaacttgt
      841 aggtgaacat aaaacggttg cacatcatac acctgcaata gttgtaccta aaggaaatcc
      901 agctaatatt caaaaattgg aagacttaaa taaagatgga gttaaactta ttttgggaga
      961 caaagagtct aatgctatag gtaagactac acaaaaaata cttgaaaaaa ataatttaaa
     1021 atctataaat gataatgttg tctctacagc tgcaactgta aatgaaatga ttgtacagtt
     1081 aacatcaagt aaagctgatg ctacaatagc cacaaaagat tcggtctttg gcaatgaaga
     1141 tgtagaagtt atagaaattg cccaagataa aaatatagac caacttatat cagcaggaat
     1201 cgtaaactat agtgataaaa aagatttagc taataaattt ataaattata tagagtcaga
     1261 cgaagctaaa cagatattta aaaaatatgg ttttgaacct gttaagtagt gattaaactt
     1321 gaaaaataaa ttttttacta ctctacttac tggatttttt gctatagtct ttttgtttat
     1381 tgtatcacca cttcttatgt taatcattaa agggataagt tatgttccta tatgcttaaa
     1441 atcagtggaa gtacagtatg caataatact tagtattaaa acatctttaa tatctactat
     1501 agtatgcctt ttattagcta ttccagtagc atatttttta catattacta aattaccatt
     1561 taaaaaactg attatacaga taataaatct ccctatgtct cttccacact tagtatcagg
     1621 aattgctctt ttacttttgt ttggaagaat ggggattgga gattccattt ataagatttt
     1681 taagcttgat tttatattta caaagcaagg tatagtttta gcacaagtat ttgtaaatct
     1741 tccacttact attaaaatac tttacacttc actaaatgaa agtaatgaaa agatgatatt
     1801 tgttgcacgt acccttggat gtaatagttg ggaagcattt agatttataa ttcttccaaa
     1861 tctaaaaact ggaatcatat ctgcaactgt aatgacttgg tcaagagcac ttggtgaatt
     1921 tggtgcagta gctatgatag caggttctac acgtatgaaa actgaaatta ttcctacatc
     1981 tatatattta aatatgtcta ctggtgatat agacattgca atcggaatag ctgtaatttt
     2041 gatatttatc tcacttacat gcttgatgct ttttgagata ttttttaata gagaggttga
     2101 taagaattaa tatgttaaaa ataaaaaatt tatctcttga tttacctaat tttaaattac
     2161 aagaaaatag tttaaatatt aataatcatg aatactttgt tttattagga gctagtgggt
     2221 caggtaaaac tctatttcta gaaacattag caggaagata tccatctgct aaaggaaatg
     2281 tatcatacaa agaaaattta atatcaaact tacctccaga aaatagaaat ataggatttg
     2341 tatatcaaaa ttttgaatta tttccaaata tgaatgttga agataatata aggtttccac
     2401 ttaaattgag aaaaatacct atagatgaac agattcttaa ggctaaccac ttatctaaat
     2461 taatgcagat agaagatata aaaaataggt atcctaaaaa tttaagtgga ggtgaaaagc
     2521 aacgagttgc ttttgcacgt gccttaatag ctgaacctga tatattactt ttagatgaac
     2581 ctatgagttc attggattat attacaaaaa aacatataag caaaattttg aaggatgtct
     2641 acataaaata caaaccaaca gtgattcatg ttactcatga tatttctgaa gcaatgtttt
     2701 ttgctcataa gataggaata atgaacaatg gaaaaataaa tcatattttt gatttaaatg
     2761 aagaaataaa aaataaagga gaatcttttt tctatgaata tatttgatat tttgagagat
     2821 tatctattag tacaagttga taaatataat ttaaatatgg atatgataag tattgtgtcc
     2881 aaatctctat cttcaaaaga agcaattgga aatactaagc gtaaagattt cccaattata
     2941 gttggtaaag aaataatgct tgaagctgac tttaaaggag ctaaaggaca agcatttact
     3001 tctactccat ctacatttga aggttcttta aaagacatat tatcattaga tttacatgac
     3061 aatcctcatg atagaagtct ttttatagca tcattaaatg cagttatgaa atacttaggc
     3121 aagacggata gaaccattca ttgtaaaaat aacgagccag agatatgtgc aaaaaaattc
     3181 cctgagttta taaaaatgga atttggtaat ccaaaagtag caattatagg atatcaacca
     3241 gccataattg ataatattaa ggactttttc gaaacaagag tattagattt aaatcctgaa
     3301 tttgtggata ctatccaata taatgttaag attgaagatg gtatacgaga ttatgaagat
     3361 gtaatatctt gggctgattt agtgatttgc acaggaagta cattatgtaa taactcaatt
     3421 ataaattttc tatcacttaa caaaccagtt tactattatg gaactacgat agctggtgca
     3481 tcaaatattt taggtttaaa aagactctgt ttttgtagta aataagcaat catatcatca
     3541 aggagtacac aaatatatat gtgtactctt taaatttaaa aagttattac ttttattcta
     3601 agtactaaag taaaattcta ttaaaatgaa tcccgaataa atgtacaatc cctttaaatc
     3661 tcaattccta tcaatcatta atattttgat tagtcttata cataaatgtt ttctttattt
     3721 taaactaata aaaaaatttt attccattaa tctactctat atttttcagc atttaagaaa
     3781 taatttttag tactttgttt gataatataa ctaagacaac ttttcaggag atgattaaat
     3841 gacatttaag aataaaaaat ttactataaa taaatataaa attctatcta ttattctagt
     3901 tttatgtttg attttaaccg cttttagtag ctatgtgaat tatagtcata aaaaatttaa
     3961 agattatgtt gtcttctatg ttcagcatca agatgatgaa gtgttgtggg ctgggagtgc
     4021 tattgttaat gctataaaag aaagaggaaa aaatcatgta tttgtggttt tagtatctac
     4081 tggatgtggt atatccgtct ttgataaata taaaaaatat gaaaacctaa caaatataca
     4141 aaaatcagaa tatagaaata gagaattttt agcttctctt aatagccttg gtgtaataag
     4201 ggaaaatata atattattac cagaaacaaa tacaaatggt aatactgact tcaattacat
     4261 ggaaaaaatt gctcttacat ttgaagaaaa atttaaaaat gtaactcata tagcacatac
     4321 ttataagtta gatgaccatt tacaacattt aaaaaatggt tctgttatcc aaaatttata
     4381 taatgctggt aaaataaaag atgctaaata ttttgtaaaa cctaaatttg ctgataaaat
     4441 aacttttaat aataagatag tttataaagc tcattctact gaagactatg aaaaggttaa
     4501 aaatgcctgt caacaataca aaattgttga tgaattagaa tatagagaag gtattggcta
     4561 taagtctgac cataaatcat ttgataagtt attaaataat aaagatgttc ctgctatact
     4621 tcatacacct aatttataag aaatatttat tcttttaatt taagttataa aaaggaaatt
     4681 atttgagatt ttgtgatata gcactttttg tgctatacta ctttttctca tacaactatt
     4741 acccatatct aatttcatca tctcttaaaa tatataaaga tatcatcatt aaaacctata
     4801 agccttatta aatgctttat acatatctac attaagctac ctatttatat taaactacat
     4861 taaaataaat atttgttata aattcttaat aattatgaaa ctcatttgtt atttatattt
     4921 gttaatatat gtttaaacct aaaaaattaa taaaccaaaa taacataagg agtgtgatag
     4981 attaccctag atattttcat aaacttttac cttcagatta atatgggcgt ctatactttt
     5041 aaatttacta tatgcattga caatatatta aaagtactag tttttatttc ataatgaacg
     5101 ggcttactgt tttctaatac ctctttttgg tataaaataa aaattggtta aaaataaaat
     5161 ttcaaggggg ttaataagtt gaatcaaaat atattggttg tagatgatga tagagagata
     5221 gttgatgcta tagagttcta tttgagacct gataacttta atgttttaaa ggcatatgat
     5281 ggacttgaag cattggacat actaatcgaa aatgatatta agttaataat aatggatgta
     5341 atgatgccca atttagatgg gcttaaaact acacttaaaa taagagaaaa aaggaatata
     5401 ccaataattc tcttatctgc aaaatcagaa gatatggaca aaattatagg tcttaatatg
     5461 ggtgctgatg actatataac taaaccattt aatccactag aacttactgc tcgagtaaaa
     5521 tctcaactta gaaggtatat aaatttaggt gattttagta atacaaataa ctcaaatgat
     5581 actaattata ttctaaaaag tggtggccta gagctaaata cagatacaaa aatagtttct
     5641 ttagatggtg aagaaattaa aatgacacca cttgaatata aaatacttac acttcttatg
     5701 tcacgaaaag gtaaaatttt ctcttctcat gagatttatg aaaatgtctg gaatgaggat
     5761 gcttatagtt gtgagagaac tattgctgtt catattagaa gaattagaga aaagattgaa
     5821 attaatccaa aagaaccaaa atatttaaag gtggtgtggg gcattggtta caaaattgaa
     5881 aaacttaatt attaatgatt ctaaagcaaa atttatttta ttattattac tgtttctatt
     5941 agtttctata ttatttgaag cagtttatga tttgaataat aacttttctt ataatattaa
     6001 ttattattat aaagagtttg ctctccctta tttttatttt ttcggtactc ctgtacattt
     6061 gtcaaaagta gaattagagt ttgtctgcat aggtattata ttatcaagtt ttttattgac
     6121 tatactatgt tttacattgt ataaaaaaaa taaacagact aaagtcaaat tcttagagaa
     6181 tgtcataagc cttttttcta aggtaaaaat agaacttaca cttatattaa ctttgatact
     6241 attaacctta aggtttcatg catttacaag taataaaatg ttttacaaca ctaatttaat
     6301 aatctacaat tttataatta tatctatagt ctatataata tatgaaaata ttaaatataa
     6361 taactataat ctaaaagata tgtctataac atatgtattt ttttcaaact tgcttaatat
     6421 gtataataaa aaaactataa ataaaaaatt agctatagta tttttaatat ctatagttgt
     6481 acaagctatt atccaatatc ttgttttgat attctttatg tatatatatt atgctgaggc
     6541 aatagctata gtaattttat ttacacttgt aaacacagtt tttcattttt atatatacaa
     6601 ctttttatct gttaagttta attacataaa taacatatca aaaaatataa aaaatataga
     6661 aaatggcaat ttaaagtata aattagaagt tataggagat gatgaaatat ctactttagc
     6721 caaaagtata aataatataa caggtggtct tgaaactgct gtagatgcta atataaaaaa
     6781 tgaaaggatg aaggcagagc ttatcacaaa cgtatctcat gacttaaaaa ctccacttac
     6841 atctatatta agctatgttg atatgttaaa aaataatgac tttgacagag agactataaa
     6901 tgactatata aatattttag ataaaaaatc acaaagatta aaattattaa tagatgacat
     6961 atttgaagca tctaagctaa gtagtggaga tgtagaattt aatataacaa aaaccgatat
     7021 aagagaactt ttaattcaaa gtattgtaga gtttgaagac aaaattcaaa atagcagttt
     7081 agattttata atagaaacac ctgaatatgc tgtttttacc atgatagatg gtaaaaaaac
     7141 ttggagagtt tttgagaatc taatttgcaa tatactaaaa tactctatgc ctaacactag
     7201 ggtctacata gatatgttta taaaggaaga aaatataata ttaacgttta aaaatatttc
     7261 aaatgataaa ctaaatctaa agccagaaga gttaatagaa agatttagaa ggggtgatat
     7321 atctagaaaa acagatggct ctggtcttgg tttatcaatt gctcaaaata taattgaatt
     7381 agaaaatgca cacatggaaa taattataga tgctgattta tttaaggtaa tgcttacttt
     7441 tagaagagtt aattgatata ttgatataaa aatatatttt aagttattta aacaagaaaa
     7501 aaacctcctt agaggtcttc ttctaaatgt tggggtttat atttacatat tttttgatta
     7561 tacctttttg gtgtgatatt aatacatttt aaattatatt tctctataat tcatcacata
     7621 tttcatctct ctgtatctat aatatcacat agtgtttcca taatcagtta catctctgtt
     7681 acctaagatt acaattttgt aatatttgta atcttaggta caaatttaca tttattcttc
     7741 aatataaata tattctttct atttacccta aagacctttt aaatcatatt tttctaagaa
     7801 aagttttaac ttagaataaa tttgttctgc tccgccaatt ttatttgatt caatatttaa
     7861 agctaataat ggttcatgta gtgatattct aagtaaaaac catccatctc catttgattc
     7921 atcacaatta actcttatgc cttcaaaatt atttggtgct acagaccatc catcaatact
     7981 cttgacatga gaatctaaat cttttaatat atcctctgca tatggtctaa aatcttcttt
     8041 attaatgcct attctaactt ctttctcttc ttgagcttct tcaaggtttt ctatcaattc
     8101 ttctatagtc tttccttcca aggatagctt tgctactttt attaaaattt tagctattaa
     8161 atatgcccca tcatctaaga aataattttc ttttaaagca gcatgtccag acgtttctat
     8221 agctaaatgg cactcttcac cttcactatt caatcttata gcttcattta ttacattttt
     8281 atatcctctt ttaaatctat gatgtcttcc ttgtaattca tttataaatt tagcaagtcc
     8341 ttcagaagta atcgaatctg ttactatagc tgtttttgga tgttcttcta atactattga
     8401 tgatataaca gctataagag catttttatt tattggtttg ccatttttac ctacaatagc
     8461 agctctgtct acatctgtat caaagattat tcctaggtcg ctcttattat ctaacacagc
     8521 tttacatatg ctttccattg cttctttgtt ttcgggatta ggtatatgat ttgggaacat
     8581 accatctggg ttcaaaaact gactacctgt cgtatctgct cccagtatgt gtaaaacttt
     8641 ttcagcaaag aatccaccag ccccatttcc tgcatcaacc aatatcttaa gcccagaaaa
     8701 aggcttttca taatttttac ttgaatttac accttttcta attttatcta tcaataaatt
     8761 agaataatct tctattaaat tttttactat aacttcacct tttttattta cttcctcata
     8821 gtctacacta tcatttttaa cagctatatc caacatctct tttatatcag ttttttctaa
     8881 acctccactt tctgtgaaaa actttaaacc attatagtaa taaggtaagt gacttgctgt
     8941 aatcataatc gccccatcag aattgtatcc atccataata gttgtcataa acatagctgg
     9001 agttgtggca atctcacaat caattacatt acaatcgtca ttagttaaag tttcaataac
     9061 agtacttcta aattggcttc ctgttatcct agaatcagtt cctatggcaa cagttacttt
     9121 atctttctta gtcttttctt ttaaccaaat atgaaacgct ttagctattt tttttacttc
     9181 ttctacagtt aggttaactt ctttagaatc attttcatac gctattcctc taatatcagt
     9241 accattttgt agtttatata ggtctcccat aaaaaattct ccttactcaa ccaaaatttt
     9301 tattaaatat tataaaattt cttgtttcca cctaaatttt tactattaaa cagaaacata
     9361 ttataatttt attacatggt tactttatac tttcttttag ttcttctatt ttatctttat
     9421 atgaaattgg aggcttatca ttaaataaag ctgaagtacc aacaacatat atatctactt
     9481 ttttaccatt cataagttta atagtatcct tatttatatt tccatcaacc tctataaatg
     9541 gaggattatc ataatctttt agtatctctg taagtttatc caacttatcc aatacagaaa
     9601 gattaaactt ttgacctgca aaccctggat ttactgtcat tactaagata ccctcaacta
     9661 aacttatata ttcttctatt ttatccacac ttgtttgagg gcttattgct aacactggcc
     9721 ctataccata atttcttaac ttttgtatat cagcttttac atttgtactt gattctacat
     9781 gaaaagaaat atattttggc tttatataag acatcatatc aatatattta tctggagttt
     9841 ctgtggctaa gtgtatgtct aaaggtattg ttgtattttc acttattgat tttaataact
     9901 ctggtcccat agccaagttt ttaacaaata ttccatccat aacatcacaa tgaagtaatt
     9961 ttacacctgc ttcttcaaga gcttctaatt cctcttttaa cttcatttgg tctgcacaca
    10021 ttattgaagc acaaataata gacataacgc tcccccttgt tataaattat atatttataa
    10081 attttctttt tctatatcat caatcatttg taatcttctt gcatgtcttt ctccattata
    10141 acttgaattt aaccattctt caacaattct cattgctaat cctttcccaa taactctttc
    10201 tcctaaacaa agtacatttg tattattgtg ttctctagtt gccttagctg aaaaacagtc
    10261 agaaacaaca gctgctctga ttcctttaaa cttatttgct gcaatagaca tacctattcc
    10321 tgttccacaa caaagtatgc ctaaatcaga ttttttactt tgaacatttt gacttacctt
    10381 ttttgcatat attggaaaat ctacactttc ttttgaattt gtacccacat cttcaacttc
    10441 tataccttta tttattaaat tttcctttat atattccttt aattcataac caccatggtc
    10501 acatccaata gatattttca ttaaatagca cctcttttta taattttttt gattactttc
    10561 agactatttt ataattatca taaaaataaa gtattgtaaa aataaagctg tcccattgta
    10621 gaaatttctt tctattttta agacagcttt aattgactta tgtcaaatca atttgttatt
    10681 tagatatatt tatatctata acaactcttt tatatttttt actatatctt ctgtagttaa
    10741 accatagtgt tttaataaat cagctggtgt acctgattga ccaaatacat ctttaacacc
    10801 aattcttcta actactacat ctttagtttc tgctaaagct tcacatacag ctgaacctaa
    10861 accacctatt atactgtgct cctctgctgt aactactttt ccagttttct tagcagtttc
    10921 ttttattaat gcttcatcta atggttttat tgtagatata ttaacaactt ctacatttat
    10981 accttcttta gcaagttctt ctgctgcttc taaggctttt gctaccatta ttcctgtagc
    11041 tattactgtt atgtcagaac cttctcttaa aacagttcct tttcctattt caaatttata
    11101 attttcactg tttacatcag gagttgcagc tctacctaat cttatataaa caggtccatt
    11161 ataatcaata gatgtaagaa tagcttgtct tgcttctaaa gcatctgctg gatttaatac
    11221 aaccatattt ggtatacctc tcattagaga tatatcctct atagcttgat ggctaccacc
    11281 atcttcacct actgttacac ctgcatgagt agctgctatt tttacattta aatttggata
    11341 tgctacagag tttcttattt gctcatagcc tcttcctgct gcaaatattg caaaagtact
    11401 cgcaaaaggt atttttccac aagtagcaag acctgctgct gtaccaatca tgtcaccttc
    11461 tgctatcccc atgtcaaaaa atctatctgg ggcaacttct ttaaatgata tactttttgt
    11521 agcttttcct aaatctgcat ctaatactac tatatcttta ttttctgcaa gttcttttaa
    11581 cacttgtccg taagcttctc tagttgctat tcccattcct atagacctcc ttctaaatct
    11641 ttcaatgctt gctctgcttg ttctgcattt ggagctgttc catgccatgc agcattattt
    11701 tccataaatg aaacaccttt accttttact gttttagcta ttattacagt tggttttcct
    11761 gtaacttttt tagcttcatc aactgcattt cctatttctt caaaagaatg tccatttatt
    11821 actattacat tccatccaaa agatttgaat ttgtcatcta ctggacttac attcattact
    11881 tcttcattag aaccatctat ttgtaatcca tttaagtcaa caaatgcaat taaattatct
    11941 aatttgtaat gtgatgctgt cattgcagct tcccatattt gaccttcttg gatttctcca
    12001 tcacctaata tagtatatac tgtatagtct ttgttatcta attttcctgc aagtgccata
    12061 ccatttgctg cagatagccc ttgaccaaga gaaccagtag acatatcgat tcctgctact
    12121 tttttcatgt ctgggtgacc ttgtaactta gaaccaaatt ttcttagtgt tattaattct
    12181 tcttctggga aaaatccttt ttctgctaat gtagcatata aagctggtgc tgcatgacct
    12241 tttgatagaa caaatctatc tctatcagcc atttttggat tttctgcaca tacgttcatc
    12301 ttatcaaaat ataatactgt caacatatca gctattgata atgaaccacc tggatgtccg
    12361 cttttagctt ctgcaaccat ttttattatg ttttttctaa tattattaga atgatctcta
    12421 agagtgctca tactttcttc ctcctgttat tttttaagac cttacatttt tttatcctac
    12481 agtagatttt acaatttttt ttaaaataat acaaatgttt ttttaagatt ttactgctac
    12541 ttttatttct tccccgttca ttaaagctgt aataccttct ttaaattcgt ctaaaccaac
    12601 agttctagta actaaagctt ctgtatttac tttcccattt gccattaaat ctaatgctgt
    12661 aatccaagaa cttggctttt gagacctgct tcctatatat tgtaactctc tttggattat
    12721 tgcttcttgg tccatttcat ttaatttttt agcaaagatt ccaacttgta cgaaagtacc
    12781 tttttttcta agcagtctta aggcttcgtt aactgctggc ataaacccag aacaatcaaa
    12841 tcctttgttt actccatttc catcagtcat ttcattcact acatctgcca aactttcttc
    12901 cattacattt acagttctat ctactccaag atttttagct atttctaatc tttccttatc
    12961 ttttgtaaca ccagacatta taactgtagc accttgagat ttaacaactt gagctaataa
    13021 taaaccaatt ggtcctggtc ctattattaa aactgtatca gaactttcta tagtagtctt
    13081 ttcaagagct gcatgaacac aacaagctag tggctctgta agggctgctg ataataaaga
    13141 tacattttca ggaagtacat gtatgctttc ttctcttgat aatacatact cagcaaaact
    13201 tccatttact tgagtaccaa taccttttct agttgggcat aagttataat ctttagtttc
    13261 acaatatata catttctcac aagttgcaaa agtagtctct gatgtaactc tatctcctac
    13321 ttttatattt ttaacatctt ctcctacttc tacaacaatt ccagaaaatt catgacctaa
    13381 tgttactggg gcttttatat ttgcatattc acctttaaat gaatgtatat ctgaaccaca
    13441 tataccacta tattctactt ttattttaac cttgtctcct gtagcttttg gttcttctac
    13501 ttctaaaact tctacattat catagcctgg tttagtttta actactgctt tcattatttt
    13561 tcaacccctt gtggtaaaat taatattttg ttaaattctt cttttctatc tcttatcatt
    13621 tcaaatgctt tgtaagtatc ttcaagtgag aatctatgag ataccatttc ttttaatttt
    13681 atctttcctt cattaactag attgattccc ttagtccatt cttgtcctgg aaatggtgca
    13741 gaataagagt tccaaaaacc ttttaattct agttcttttc taaatatatt ttcaaatgct
    13801 tcttctgata aagttatatc tgaatatgct atccctaaaa atcctatctt acttttcttt
    13861 ttagttataa gtaaacattg ttcttgagtt atttttgaac ctgcacattc aagagctatg
    13921 tcaacacctt ttccaccagt aagttctttt attttttcta ctgggttaat atctttagca
    13981 ttaattatta tatcagcccc taattccttt gattctctta atttattatc agatatatca
    14041 actgctataa ttgttcctgc ccctgctatt ttaagtcctt gtattaccaa ctgccccatt
    14101 gttccactac ccattacagc tacagtgtct ccaacttgaa cacctatatt aagtactcca
    14161 tgcatagcaa ctgctagtgg ctctatcatt gcagcatctt caaagttcat atctcctatt
    14221 ggaagtacat ttgtagcttt tatatttaca tactctgcaa aagctccaaa acttttagct
    14281 cctaacattc catggtcatc acacaatgaa aataatcctc ttttacaata ttcacattca
    14341 ttacaaggta taaaaggaat tgcaactact ctatctccaa cttttacatt ttttacatcc
    14401 ttaccaactt cagcaattac tccagaaaac tcatgtcctg gtatagctgg aactggatat
    14461 ttccaatgtt ttaatactct tggaggatct gacccacata ttcctgctgc cataactttt
    14521 atttttactt catcactttc acatggtttt atttctatat cttcaaatct catatcattt
    14581 gtgccatgta atactgctgc tttcacgata aatctcctcc tcttgtattt tgtattttta
    14641 aaaatttata aaaaatatta ctctttttta gtagctgcta aatgttaaat tttcgcatac
    14701 tttactaaaa aagagtaatc tctattaact acatactaga atattccaaa tgaagaaact
    14761 aattgagata atttcaatat tccccatttt agcaagtttc cacctgtatc tatacttgta
    14821 accattgttg ttccttctgg catcatattt gcttgttgta ataattgtgt atgaacatct
    14881 gcaaagtttg tagccatata aagtgatata gctattacta ttgttcctgt tataactgat
    14941 tgaactatat taccttttct aaaacacact ataaatgcca tataaaatgg tattgtcgct
    15001 aagtctccaa atggtaaaac tttgtttcct ggtagtataa ctgctaagaa caaagttata
    15061 ggaacaagta taagagctgt tgatataact gctggatgtc cagttgctac tgctgcatcc
    15121 agacctatat aaagttctct gtctccatat tttgcttgta agaaatctct tattgattct
    15181 gaaattggaa ttaaaccttc cattaatatt ctaaccattc taggcataag taacattact
    15241 gcacccattg atatacctac attgaatatt cctgctacat catatcccgc aagtgctcca
    15301 agtattatac ctagtataat ccccatcatc attggttctc caaatatacc aaatcttttt
    15361 tgtatagagt ctgggtctgc ttgtatttta tttattcctg gtattttttc aacaaattta
    15421 cctactaaat atccaagtgg agcaaatgaa gctgttgaac cagttggtaa tgctatacct
    15481 tctaaatcat aaaactcctg aacatttttt gctgtctttt ctgcaataaa cagtactaat
    15541 aactccatta gtattgcaca gaatatagcc caaacataac ttcctgttac tatatatcca
    15601 actgcacctg ctactataaa gtgccaataa ttccatatat caacgtttaa tatctttgtt
    15661 ttattgaagt ataataatag taagtttact aataaacaaa ctggtattaa tattggtgca
    15721 actggtgaag cccatgttgc tgatgctgtt gttggccaac caacatctat tactgttaaa
    15781 ttaagtccga atctttcaac cattccttga gccgctggcc ctagtgttga tgttaatagg
    15841 tttacaacta agtttatacc cacaaatcct ataccaattg taagacctga ctttaaagct
    15901 tttgtaaact taattctaaa tatcattcct agtactacaa ttgttattgg tagtattact
    15961 gtcggtccca tatttaaaat gtattgtact actgctaata atttatccat ttataaatcc
    16021 tcctttttct gttttataaa atattatttc aatgtatcta tgataggatt attttaaagc
    16081 atctaatatt tttttatcta atgctgctgt atttactcca gttatatatg ctgttgcttt
    16141 tattgctggt atattataag ttgttggtag tatagttgtt gatactatta aatctgctcc
    16201 ttcttgcttt gttgcacatt cagctatttt gcattgtata acttctgctt gtatattatt
    16261 ttccttaact aatctctcta ccttgtcaca aactactgtt gatgttgcta ttcctgctcc
    16321 acatgctact aatatttttt tcatttttat ttcctcctaa taatttttat ttttatattt
    16381 tttattttta gtactttttt atttttataa agactttagt gtctttaaaa cttcttcttt
    16441 atcagtagaa ctcatcaact tatcaactaa ctctttattt tgcataattc ccattaattc
    16501 tgttaataca gataattgac tgtgtggttg attaagtcct aatacgaaag ccaaatttac
    16561 aggtactttt tcatcttggt cttccataga actaaatact actggttcat taaaagtaca
    16621 gactgatata aattgctctt taatatattc cgcatctgta tgtggtattg ctactccata
    16681 atcacctaaa tttaaacctg ttggaaatac attttctctt gctaatattt tttctccaaa
    16741 ttcttctttt acaaagccta aatcaaaaac tttattatgt atttctttaa agaaatcttc
    16801 tttcgtttta caatccattt taaggtctat aactttatca cttacaaaat ttataaactc
    16861 catatttaca cctcctaatt gcctttgtct tataccttag tttttcttga ctttatataa
    16921 agcatgttgt gtgccaaaaa gtggcttttt ttgtgaaaca aaagaaaatg ttttcccaaa
    16981 aataatgctc tcttccagga ttttagctga ctttcattga taaatttttt ttgattttta
    17041 ttttaatttt tacttgttaa tcacttaact agccatactt ttttata
//
LOCUS       DAYAOO010000089        17030 bp    DNA     linear   BCT 12-OCT-2024
DEFINITION  TPA_asm: Clostridioides difficile isolate ST8-SSI-h139-18
            SAMN40601845-rid21577343.denovo.090, whole genome shotgun sequence.
ACCESSION   DAYAOO010000089 DAYAOO010000000
VERSION     DAYAOO010000089.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN40601845
            Sequence Read Archive: SRR28438827
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 17030)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 17030)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-MAY-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-MAY-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002157583.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002157583.1
            Genome Coverage       :: 163x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/11/2024 16:19:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 4,038
            CDSs (total)                      :: 3,963
            Genes (coding)                    :: 3,930
            CDSs (with protein)               :: 3,930
            Genes (RNA)                       :: 75
            rRNAs                             :: 6, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 60
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 33
            CDSs (without protein)            :: 33
            Pseudo Genes (ambiguous residues) :: 0 of 33
            Pseudo Genes (frameshifted)       :: 7 of 33
            Pseudo Genes (incomplete)         :: 25 of 33
            Pseudo Genes (internal stop)      :: 11 of 33
            Pseudo Genes (multiple problems)  :: 8 of 33
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..17030
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN40601845-rid21577343.denovo.090"
                     /isolate="ST8-SSI-h139-18"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Denmark"
                     /collection_date="2018"
                     /collected_by="Statens Serum Institute"
     gene            complement(124..648)
                     /locus_tag="ACGI5H_003142"
     CDS             complement(124..648)
                     /locus_tag="ACGI5H_003142"
                     /EC_number="5.2.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434191.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003755 - peptidyl-prolyl cis-trans
                     isomerase activity [Evidence IEA];
                     GO_process: GO:0000413 - protein peptidyl-prolyl
                     isomerization [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase"
                     /protein_id="HFG9698834.1"
                     /translation="MENKNPIVTIEMENGKEIKIELYPNIAPNTVKNFVSLVNEGYYN
                     GIIFHRVIPGFMIQGGCPNGTGMGGPGHSIKGEFSGNGFTNNLKHERGVISMARTMAP
                     NSAGSQFFIMHKNSPHLDGQYAGFGRVIEGMDTVDEIASVRTDSADKPQTPQVMKSVT
                     VETFGIDYSDVEKN"
     gene            complement(713..1465)
                     /locus_tag="ACGI5H_003143"
     CDS             complement(713..1465)
                     /locus_tag="ACGI5H_003143"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417271.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="patatin-like phospholipase family protein"
                     /protein_id="HFG9698835.1"
                     /translation="MKLGLCLEGGGAKGAYQAGVVKALYDGGINKFYSISGTSIGAIN
                     GYYLYTGNVDNLEKMWTNIKDIQNGNVKIVNNTVDNSPAIDNLRELDDSNIEEMNFYV
                     NYVEVDNKVVSEKIVDVSKMPRNEAIISISYSGLLPSNPNATLGFKEQFVKDVQEGIY
                     DGFKLDGGLIRSALIEPLIGDNVDKIILISTKYNYELPEDIKKVYDEDKIIVVRPNTQ
                     FAPKDTLNFDDEFCKTIYQEGYEIGKNILDRL"
     gene            complement(1496..2794)
                     /locus_tag="ACGI5H_003144"
     CDS             complement(1496..2794)
                     /locus_tag="ACGI5H_003144"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888187.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004177 - aminopeptidase activity
                     [Evidence IEA];
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="M18 family aminopeptidase"
                     /protein_id="HFG9698836.1"
                     /translation="MDSINFAKNLIDFIYDSPSSFHAVESTKEILDKNGFEELVLNQR
                     WNLRVGGKYYVTKNLSAIVAFVVNSEGIERDGFRIIGSHSDSPTFSIKPNAEIEAEKS
                     YLKLNTECYGGAILSTWLDRPLGIAGRVVLKGDSILKPNERLIDFKKPICIIPNLAIH
                     LNRSINDGHSYNKQKDMLPLVGMLNDTLEKDNFLIKQIASNLDVNMDDIIDFDLFLYE
                     FEKGSLIGANDEFISIGRQDNLAMVHASLNALVNTKGQHGVNVMAVFDNEEVGSSTKQ
                     GADSNMLLNILERICISMGKDREGFFESIYSSFMISSDLAHAIHPNIPEKHDPTNKPI
                     MGKGPVIKINASQAYTSDGYSIAIYKNICREANVEYQEFVNRSDERGGSTIGPISSTH
                     IDIPSVDVGSPILAMHSIRELGNVEDHYSIYKTFSKFFEI"
     gene            complement(2811..5075)
                     /locus_tag="ACGI5H_003145"
     CDS             complement(2811..5075)
                     /locus_tag="ACGI5H_003145"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3553 domain-containing protein"
                     /protein_id="HFG9698837.1"
                     /translation="MNLDTLNPAQREAVEKTEGPVLILAGAGSGKTKVLTTRIAYLIE
                     DKGVQAPNILAITFTNKAANEMRERVEQNIGPETKDMWISTFHSCCVRILRKDINKIG
                     YNRSFVIYDSADQVTLVKDCLKELNLSDKVFEPKAVISAISGAKDKLYTPKQFKDINM
                     ADNRMVKIADIYALYQDRLKRNSALDFDDLILKTVELFKANDEVLAYYRSRFRYIMVD
                     EYQDTSKAQYELIKLLAREHQNICVVGDDDQSIYGWRGADIRNILEFEKDYDNVHVVK
                     LEQNYRSTQVILDAANKVISNNIERKRKKLWSEKKEGELIKIQLTGSEIEEADFIADS
                     IAQIARKENRPYKDFAVLYRANAQARPVEDALNRSQIPYNIYGGTKFYERKEIKDLLA
                     YLRVIQNPQDDISIKRIINVPRRGIGLRTIEKIEDRANLKQESIYSVLIDIETNSDIS
                     TKARASISGFVDIIGTLRTIKEVYPVSKLIEKVLDTTGYMDELVEIRNKNEKDLTGKG
                     EEAQDRIDNLREFISIALEFESSNDDTYENKDLETFLTSIALTSESNDEEDNDRVSLM
                     TIHTSKGLEFPVVFLTGMEEGLFPISRAIKSMSDSQIEEERRLCYVGITRAKEELYMS
                     LTEKRTLYGKTNVAIASRFMEELPEECIERLYKVKKELSYSKASYNMLDKYTKKYMST
                     ISKSKVADKVNATIKDSNKETNPDDIKLGSKVHHPKFGVGTVVSIIGTDVTIAFDQQG
                     IKKINKEYTTLNIL"
     gene            complement(5330..6148)
                     /locus_tag="ACGI5H_003146"
     CDS             complement(5330..6148)
                     /locus_tag="ACGI5H_003146"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009904855.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor ABC transporter
                     ATP-binding protein"
                     /protein_id="HFG9698838.1"
                     /translation="MFKINNLTYQYEKNTNALLNINMDFSKGNVIGIIGSNGSGKSTL
                     FMNLMGILKPTSGEILFKEEKLKYDKRSLYNLRKNVGIVFQDPEKQIFYSKVYDDIAF
                     AMRNIGMDEKTIKERINKALVAVNGIDFIDRPVHFLSYGQKKRVAIASVIAMENEIVL
                     LDEPTAGLDPVSTRSIVDIIKGLNKNNIKIVISSHDMNLMYEICDYIYVLDKGILIDE
                     GKAENVFINENNIIQAGLESPWLVKVHRNMNLPLFKKEEDLYKYWKERELNTNK"
     gene            complement(6141..6839)
                     /gene="cbiQ"
                     /locus_tag="ACGI5H_003147"
     CDS             complement(6141..6839)
                     /gene="cbiQ"
                     /locus_tag="ACGI5H_003147"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417243.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_component: GO:0043190 - ATP-binding cassette (ABC)
                     transporter complex [Evidence IEA];
                     GO_function: GO:0032778 - P-type cobalt transporter
                     activity [Evidence IEA];
                     GO_process: GO:0006824 - cobalt ion transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cobalt ECF transporter T component CbiQ"
                     /protein_id="HFG9698839.1"
                     /translation="MLIIDKYAYTNRLSKVNPNKKVAIGVIFLIASMVIQNIFILSGI
                     MILMSILVVCVAGIDLKNYLKLLRIPMYFLFLSIGITLVNISFNKADLLYSFEFFSFN
                     VGISKASINMSIHVLFRAMSCLTCVYFCILTTPFNQLIFFFKKLHLPDTFVELSMLIY
                     RFIFIFLEEFSEIYKSQELRFGYINLKTSYKSLGILGSMLYKRLMTRYDDMCISLDIK
                     LYDGKFHIVGDNDV"
     gene            complement(6842..7126)
                     /locus_tag="ACGI5H_003148"
     CDS             complement(6842..7126)
                     /locus_tag="ACGI5H_003148"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895390.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0015087 - cobalt ion transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0006824 - cobalt ion transport [Evidence
                     IEA];
                     GO_process: GO:0009236 - cobalamin biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor ABC transporter
                     substrate-binding protein"
                     /protein_id="HFG9698840.1"
                     /translation="MSAKTKTKTNILLLLLVVALIIFPLLVNSGAEYGGADGQAESEI
                     TKINPNYKPWFSSPYEPPSGEIESLLFSAQAALGAGVIGYILGLQKGKRS"
     gene            complement(7116..7868)
                     /locus_tag="ACGI5H_003149"
     CDS             complement(7116..7868)
                     /locus_tag="ACGI5H_003149"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427152.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_component: GO:0043190 - ATP-binding cassette (ABC)
                     transporter complex [Evidence IEA];
                     GO_process: GO:0000041 - transition metal ion transport
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor ABC transporter permease"
                     /protein_id="HFG9698841.1"
                     /translation="MKQNIKLGVIAALMLIILTPVTSNAMHIMEGYLPVKWSIAWGVI
                     FIPFFLFGLKSIGKIVKQDPKKKVLLALCGAFVFVLSALKIPSVTGSCSHPTGVGLGA
                     IMFGPSVMFVLGTIVLIFQALLLAHGGITTLGANAFSMAIIGPIVSFLIFKALKKKDG
                     NNAIPVFLAAAIGDLATYTITSIQLALAFPDPSGGVMASAIKFLGIFFMTQIPIAIAE
                     GILTVIVYNLITENGEKSILENNDKGVKANEC"
     regulatory      complement(8050..8242)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00174"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="cobalamin riboswitch; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="adenosylcobalamin"
                     /db_xref="RFAM:RF00174"
     gene            complement(8374..10146)
                     /locus_tag="ACGI5H_003150"
     CDS             complement(8374..10146)
                     /locus_tag="ACGI5H_003150"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427150.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nitric oxide reductase activation-like protein"
                     /protein_id="HFG9698842.1"
                     /translation="MKWIYDDYEFENRANNLSWTIAGDYNESIDISEKDYSSKEIGLY
                     FAIIAGARRKYVDWDIVKKYLTNRIRKGYNKDVILGLIQVILNTIVEEKVIKDRPGIE
                     DIRRNAYKDIVSRFTKIHNDNIMDKIKYTFVLYSMDKHPALDSMTRRIVNDIRNIDTN
                     QDIMEILKALDVIYLTYFEYILNGEENSLIDENNVESVEVNFDTFADFMYEELYSDEE
                     ENIIESDIDSISSSMLVEGVGDFDDSKCSNSADRVIYVDEDTANKIYSKIEHYYGKTY
                     LSKGEIKKIETQNCRNVHEGCRIHFTDGVLRSECNNVFQLKYVTRQKENNLGKFREHA
                     RMYRQQIKRLKESLSRILIEENAKSRVYSDCGTILANRAWRVGRSNNNKIFYKDIENE
                     KGKYVIDILLDASGSQSRNQGNVAIQAYIIANALTEVGIPNRVMGFSSFLDYTILKRF
                     KDYDDSIKNSENIFEYFCAGNNRDGLAIKSICSGLINRDEENKILIVLSDGRPNDVKI
                     GKSSERTLRGEKAYRGIVGLRDTANEVRKARKQNILVLGVFTGKESELEAERLIYGND
                     FIYSRDITRFSDVVSMYLKKIIRN"
     gene            complement(10160..11089)
                     /locus_tag="ACGI5H_003151"
     CDS             complement(10160..11089)
                     /locus_tag="ACGI5H_003151"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434205.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HFG9698843.1"
                     /translation="MDIIDNLRVQGVDEKLIEDVLYFRNYYGLEKDLEYRVTKSKTYF
                     YGKDILSMCIAAILEEENILLSGPKATGKNLLADNLGEIFNRPQWNTSFHINTDSSTL
                     IGTDTFIDNEVKLRRGSVYECAINGGFGVFDEINMAKNDAIVVVHSALDYRRIIDVPG
                     YERVNLHPATRFIGTMNYEYAGTKELNEALVSRFMVIDIPPIEEDKLMMILKNEFSDA
                     DEEKLIHFAGIFLDLQLKSQNGEISSKAIDLRGLMASLKTIRRGLKPTLAINMGLTGK
                     TFDVYEKEMVGDVIKTRIPNKWESIDVFPISHI"
     gene            11310..11495
                     /locus_tag="ACGI5H_003152"
     CDS             11310..11495
                     /locus_tag="ACGI5H_003152"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888180.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein"
                     /protein_id="HFG9698844.1"
                     /translation="MKYGCPEVAKKWGISERRVQKLCEESRIPGVSKLGYMWLIPKNA
                     EKPVDGRTKRRKEVQYE"
     gene            11488..12189
                     /locus_tag="ACGI5H_003153"
     CDS             11488..12189
                     /locus_tag="ACGI5H_003153"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434208.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000156 - phosphorelay response regulator
                     activity [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HFG9698845.1"
                     /translation="MNSVLIIDDDKELCALMKKCVEQENLSAITAHCGAEGLHLVDKN
                     RHTLSLVILDIMMPDIDGFQVLKKIRETSNIPVIMLTAKNDEDDKVSGLRLGADDYLT
                     KPFSINELMARVNSLIRRYTMLNPAFITDTDCIIINGMIIDKTNRIVSVNNIPVQLTS
                     KEFDLLAFLASNKGRVFTKKQIYTQVWEEEYAFDDSNIMSFISKLRKKIEPDPNHPFY
                     ILTVRGVGYRFNKEA"
     gene            12191..13114
                     /locus_tag="ACGI5H_003154"
     CDS             12191..13114
                     /locus_tag="ACGI5H_003154"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427141.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing sensor histidine kinase"
                     /protein_id="HFG9698846.1"
                     /translation="MNTSVYLLLILVLSLIIIAYLVSVLLRVRIQLTLIKDALEDIKN
                     GNLNRRILTDENDITKQICYDINEIAINSQFQLIQQKQSEQAYKQLMTSLSHDVKTPL
                     ASLVGYLEAVESKIVVGEEKDEYIHVASNKAHYLKNFVENLFEWVKLDSKEQVFHFDI
                     FDLNELSRNIISDWIPVLESSHFEYEFDIPEIEYFLRIDANAYTRIINNLLQNIITHS
                     SGNKMTLRIFENKEQAQIIITDNGKGISSDNLPHIFERLYQCDHSRASKGNGLGLAIA
                     KELINAHKGNITANSTPGMGTEFTILLPKAL"
     gene            13271..14194
                     /locus_tag="ACGI5H_003155"
     CDS             13271..14194
                     /locus_tag="ACGI5H_003155"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019639192.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HFG9698847.1"
                     /translation="MNDFVIETKQLTKIYGNQTVVDKVNLHAKKGRIYGLLGRNGAGK
                     TTIMKMILGLTSITYGEVDVFGENIKGREKQVYPRIGAIIETPGFYPNLTGTENLEIF
                     AKLRGTAAPNSVKRALEIVGLPYKNKKLFSEYSLGMKQRLGIANAILHDPELLVLDEP
                     TNGLDPIGIAEMRKFIRDLSVEHGKTILISSHILSEISLLADDIGIIDHGVLLEESSM
                     SELEKKNSKYILLQVSDIPKTSLILERQFNTKDYSVQDDYTLHLYNTNLDMGEINKAL
                     VMQNVTVISSQLCNDTLEDYFKKITGGEGIA"
     gene            14187..14924
                     /locus_tag="ACGI5H_003156"
     CDS             14187..14924
                     /locus_tag="ACGI5H_003156"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434216.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HFG9698848.1"
                     /translation="MLKLIQTEFLKLRRRKLIWLMLLSALIMPFFALLYFNYFGKTGV
                     EPIKFYKWSAFGYTLWIILPVVLGIFCTMLIHEENQYDMLKQLWIVPISKMGYFFSKF
                     FVVLIYSICFMLITAVASVLFSVLSGYVVFSWASILYLLKKCLEIGVITAFVMLPILA
                     IATSQKGYILPICITLVYAFSGFVIMTINMYLHPLSSMGVIIMRNKDIPGLIFSQEIN
                     VPLAFLCICIWSIVSVLFANTALGRRK"
     gene            14935..15708
                     /locus_tag="ACGI5H_003157"
     CDS             14935..15708
                     /locus_tag="ACGI5H_003157"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434217.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HFG9698849.1"
                     /translation="MWKLLWAECQKIRRSKIVWITVFASIMIAVIVFAGGQDVYNDPD
                     LHYGLKSVYDGSRYIDNAGWYMDAVQPWSTFFVLPAVIALLGSYIICREEEEDTIKSL
                     RLIPINETKLTIAKMIITFIFSILLYLLLFTITFLTESVLHFSDLSTKLVLSCMKEYF
                     LDGIGVFFAISPIIALVSRMKKGYWLALVFTEVYSIAGLFAGMSNVLQTFFPIAAIFN
                     ISGYYITTGEKIMGSIISLLLCACLSAFILKGLKHNEKN"
     gene            complement(16249..16857)
                     /locus_tag="ACGI5H_003158"
     CDS             complement(16249..16857)
                     /locus_tag="ACGI5H_003158"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895382.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DedA family protein"
                     /protein_id="HFG9698850.1"
                     /translation="MSVINSFILQYGLISVFVLIMIEYACFPLPSEVVLPLCGAIAAR
                     NHFGFLTILILSIIAGILGSIFCYTVGNWGGKSIINKIIEICPKAKKGIFASQDYFNK
                     YSSISVCVCRLIPLCRTYISFIAGIAGQNIITFVISSIVGITIWNTSLISIGYIFSES
                     WVRIMSHYNDYKFLVLIIPISIIFIGFVIKSFIHKKHHKIRL"
BASE COUNT         5488 a         2950 c         2154 g         6438 t
ORIGIN      
        1 aaataaatta aaaagtgaaa tgtatttgtc taaaaacata ataacatttc actttatcct
       61 catttttaag taatatatat ttttaatttt tatttataac taaatctagt ttttatataa
      121 attttagttt ttttctacat ctgagtaatc tattccaaaa gtttctacag taacagattt
      181 cataacttgt ggagtttgtg gcttatcagc tgaatctgtt ctaactgatg ctatttcatc
      241 aactgtatcc ataccttcta tcactctacc aaaacctgca tactgaccat ctaagtgtgg
      301 tgagttttta tgcattatga aaaattgaga accagctgaa ttaggtgcca tagttctagc
      361 cattgatatg actcctcttt catgttttaa attgttagta aatccattac cactaaattc
      421 accttttatt gagtgacctg gaccacccat tcctgtacca tttgggcatc ctccttgtat
      481 cataaatcct ggtattactc tatgaaatat tattccattg taatatcctt catttactaa
      541 tgatacaaag tttttaactg tatttggagc tatatttgga tataactcaa ttttgatttc
      601 ttttccattt tccatttcta tagttactat aggattttta ttttccataa tttattacct
      661 tccttttcat tagttaaatt acataattac atttattata ttatactcta aattaaagtc
      721 tatcaagtat attttttcct atttcatatc cttcttgata aatagtttta caaaactcat
      781 catcaaagtt aagcgtgtct ttaggagcaa attgagtatt aggtctaact actattattt
      841 tatcttcatc atatactttt ttaatatctt ctggcaactc ataattatat tttgtggata
      901 ttaaaataat tttatccaca ttatccccaa ttaatggttc aattaatgca ctcctaatta
      961 aacctccatc taatttgaaa ccatcataaa ttccttcttg cacatctttc acaaattgtt
     1021 ctttaaatcc aagagttgcg tttggatttg atggtaacaa cccactgtat gaaatgctga
     1081 taatggcttc attacgaggc atttttgata cgtcaacaat cttttctgat actactttat
     1141 tatcaacttc aacataatta acataaaagt tcatttcttc tatattacta tcatctagtt
     1201 cccttaggtt gtctatagca ggagaattat ccacagtatt atttactatt tttacatttc
     1261 cattctggat atcttttata tttgtccaca ttttctccaa gttatcaaca ttccctgtgt
     1321 acaaataata tccatttatt gctcctattg atgtccctga aatcgaataa aatttattta
     1381 ttcctccatc atacaaggct ttaactactc ctgcttgata agcccctttt gctcctccac
     1441 cttctaaaca taatcctaat ttcatagtct catctccaaa ttgtttatct tatatttata
     1501 tttcaaaaaa cttactaaat gttttatata tactatagtg gtcctcaaca tttcctaatt
     1561 ctcttataga atgcattgct aaaattggac ttcccacatc cacagatggt atatctatat
     1621 gagtagaaga tattggacct atagtacttc ctcctctttc atctgaccta ttaacaaatt
     1681 cttgatactc aacattagct tctctacata tatttttata aatagctata gaatatccat
     1741 cactagtata tgcctgacta gcatttatct ttataaccgg accttttccc attattggtt
     1801 tattagttgg gtcatgcttt tctggaatgt ttggatgaat agcatgagct aaatctgatg
     1861 atatcataaa agatgaataa atagactcaa agaatccctc tctatcctta cccattgata
     1921 tgcaaattct ctccaatata tttaacaaca tgtttgaatc tgcaccttgt ttagtagagc
     1981 taccaacttc ttcattgtca aatacagcca ttacatttac accatgttga cctttagtat
     2041 taacaagagc attcaaacta gcatgtacca ttgcaagatt atcttgtctc ccaatagata
     2101 taaattcatc attagcccct attaaacttc ctttttcaaa ttcatataaa aataaatcaa
     2161 aatctataat atcgtccata tttacatcta agttagatgc tatttgcttt ataagaaaat
     2221 tatctttttc taatgtatca tttaacatcc caactaaagg taacatatct ttttgcttat
     2281 tatatgagtg accatcattt atacttctat ttaaatgtat tgctagattt ggtattatac
     2341 aaattggctt tttaaagtct ataagccttt catttggttt taatatacta tcacctttta
     2401 aaactactct accagctatc ccaagaggtc tatccaacca tgtacttaat attgctcctc
     2461 catagcattc tgtatttaac ttcaaataag atttttcagc ttctatttct gcatttggtt
     2521 taatactaaa tgtaggagaa tctgaatgag agcctattat tctaaatcca tctctttcta
     2581 taccttctga atttactaca aaagctacta tagctgataa attcttagta acataatact
     2641 ttccaccaac tcttagattc catctttgat tcaaaactaa ttcttcaaat ccatttttat
     2701 ctaagatttc cttagtactc tcgactgcat gaaaagacga cggactatca tatatgaagt
     2761 ctattaagtt tttagcaaag tttatactat ccattcctca tttacctcca ttataaaata
     2821 tttagtgttg tatattcttt atttattttt ttaattccct gttggtcaaa agctatagta
     2881 acatctgtac caattataga aaccactgtc ccaaccccaa atttaggatg atgtacctta
     2941 gaaccaagtt ttatatcatc tggattagtt tctttattag aatcttttat tgtagcatta
     3001 actttatctg caactttaga tttgcttata gtactcatat actttttagt atatttatct
     3061 aacatattat aacttgcttt agaatagctt agttcttttt ttactttgta caatctttct
     3121 atacattctt ctggcagttc ttccataaat cttgaagcta ttgcaacatt tgttttacca
     3181 tataatgttc tcttctctgt caatgacata tatagctctt ctttagctct agttatacca
     3241 acataacaaa gtcttctctc ttcttctatt tgtgaatcac tcatagattt tatagctctt
     3301 gatataggaa ataacccttc ttccatacct gttaaaaaca caacagggaa ctctaaacct
     3361 ttggatgtat gaattgtcat aagcgaaacc ctatcattgt cttcttcatc atttgattca
     3421 gatgtaagtg ctatacttgt taggaatgtc tctaagtctt tattttcata agtatcatca
     3481 ttactacttt caaactccaa agctatagaa ataaattctc tcaaattatc aattctgtct
     3541 tgagcttctt cacctttgcc tgttaaatct ttttcatttt tatttcttat ctctacaagc
     3601 tcgtccatat atcctgtagt atccaagact ttttctataa gtttgctaac aggataaact
     3661 tcttttatag ttctaagagt ccctataata tcaacaaatc cacttatact tgcccttgcc
     3721 ttagtagata tatctgaatt tgtttctata tcaattaata ctgagtatat actttcctgt
     3781 tttaagttag ctctatcttc aattttttct atagttctaa gccctatacc tcttctagga
     3841 acatttataa tcctttttat agatatatca tcttgtggat tttgaataac tcttaaatac
     3901 gccaacaaat cctttatttc ttttctctca tagaattttg taccaccata tatattgtat
     3961 ggaatttgac ttctatttaa agcgtcctct acaggtcttg cctgtgcatt tgctctataa
     4021 agtactgcaa aatccttata aggtctattt tcttttctag ctatttgtgc aattgaatca
     4081 gcaatgaaat cagcctcttc tatttcacta ccagttaatt gtatctttat aagttctcct
     4141 tctttttttt cactccaaag cttttttctt tttctttcta tattattaga tataacttta
     4201 ttagctgcat ctaatataac ttgtgtagac ctataatttt gttccaactt tacaacatgt
     4261 acattgtcat aatctttctc aaattcaagt atgtttctta tatctgcacc tctccatcca
     4321 taaatacttt ggtcatcatc tccaacaaca caaatatttt gatgttctct tgctaataat
     4381 tttatcaatt catattgagc tttacttgta tcttggtact catctaccat tatgtatcta
     4441 aatctacttc tgtaatatgc taacacttca tcattagcct tgaaaagttc tacagtttta
     4501 agtattaaat catcaaagtc aagtgcacta tttcttttta aacggtcttg atatagcgca
     4561 taaatatctg caatcttaac cattctatta tctgccatat tgatatcttt aaactgcttt
     4621 ggagtataaa gtttgtcttt tgctcctgaa attgcactta taactgcttt tggttcaaac
     4681 actttatcac ttaaatttaa ttcttttaga cagtctttaa ccaatgtaac ttggtctgct
     4741 gaatcataaa ttacaaaact tctattgtaa ccaatcttat ttatatcttt tcttagtata
     4801 cgaacacagc aagaatggaa tgtacttatc cacatatcct tagtttcagg acctatattt
     4861 tgttcaactc tctctctcat ttcatttgca gctttgtttg taaatgttat agctaatata
     4921 tttggtgctt gtacaccttt atcttctata agatatgcta ttcttgttgt taatacctta
     4981 gttttacctg aaccagcacc agccagtata agtactggac cttcagtctt ttctactgct
     5041 tctctttgag caggatttaa tgtatctaaa ttcatatttc tcctcctgtt aacagccata
     5101 aatatatttt aatctaaaat atgaattact tcaaattata attatgtatt atattaatag
     5161 attatttcca atatattaca attaaataac atttttccat ataatttatt tcattgttta
     5221 ataaaaaaaa taaccttatg atttggggaa tcataaggca cctttaaggg gtctaggtta
     5281 agggttatta tatataaatc tattttttta aaataggttt agggcttaat tatttatttg
     5341 tattaagttc tctttccttc caatacttat acaaatcttc ttctttctta aataagggta
     5401 aattcatatt tctatgtact tttactaacc atggggattc taggccagct tgtataatat
     5461 tattttcatt tataaacaca ttttctgctt ttccttcatc aatcaaaatc cccttatcca
     5521 atacatatat gtaatcacat atttcataca ttaaattcat atcatgactg gatattacta
     5581 tttttatatt atttttattt aatcccttta ttatatctac aatagaccta gtacttactg
     5641 ggtctaaacc agctgtaggt tcatcaagta atacaatttc attttccatt gctataactg
     5701 atgctattgc cactcttttt ttctgtccat agctaagaaa atgtactggc ctgtctataa
     5761 aatctattcc attaacagct actagagctt tgtttattct ctctttaatt gttttttcat
     5821 ccataccaat gtttctcatt gcaaaggcta tatcatcata tacttttgaa taaaaaattt
     5881 gtttttctgg gtcttggaag acaataccta cattttttct aaggttgtat aaacttctct
     5941 tatcatattt taacttttct tctttaaaaa gaatttctcc agatgtaggc tttaatatac
     6001 ccattaaatt cataaataat gttgattttc ctgaaccatt tgaacctatt atacctataa
     6061 catttccctt tgaaaaatcc atattaatgt ttaatagtgc attggtattt ttttcatatt
     6121 gatacgttaa attatttatt ttaaacatca ttatccccta ctatgtgaaa tttaccatca
     6181 tacaatttta tgtctaatga tatacacata tcatcatacc ttgtcataag tcttttgtac
     6241 agcatacttc caagaatacc taaggattta tatgaagttt ttaaatttat atatccaaat
     6301 cttagctctt gtgacttgta tatttctgaa aattcttcta aaaatatgaa tataaaccta
     6361 tatattaaca ttgataactc gacaaaagtg tcaggtaaat gaagtttttt aaaaaagaat
     6421 attaattgat taaaaggtgt tgtaagtata caaaaataca cacaagtcaa acaagacatc
     6481 gctctaaata acacatgaat agacatgtta atagacgcct ttgatattcc tacattaaaa
     6541 ctaaaaaatt caaaactata taataaatct gctttattaa aagatatatt tacaagagtt
     6601 attcctatac taagaaataa aaagtacatt ggtattctaa gtaattttaa ataatttttt
     6661 aaatctattc cagccacaca aacaaccaaa atactcatta aaatcataat tccacttaaa
     6721 ataaatatat tttgtattac catagaagca atcagaaaaa ttactcctat ggctactttt
     6781 ttgtttggat ttactttact caatctattt gtatatgcat atttatcaat tataagcatg
     6841 attaacttct ctttcctttt tgaagaccta atatgtatcc tattacacca gcccctaaag
     6901 ctgcttgtgc agagaataat aaactttcta tttctccact tggtggctca tatggactgc
     6961 taaaccatgg tttgtaattt ggatttatct tagtaatttc actttcagct tgaccatctg
     7021 ctcctccata ttcagcacct gagttgacaa gtaatgggaa tataataaga gctactacta
     7081 ataaaagtaa taatatgtta gtttttgttt ttgttttagc actcattagc tttaactcct
     7141 ttatcattat tttctagtat gcttttttct ccgttttctg taattaaatt atatacaatt
     7201 acagtaagta taccttctgc tattgctatt ggtatttgag tcataaagaa aattcctaaa
     7261 aatttaattg ctgaagccat taccccacct gatgggtctg ggaaagccag tgctaattgt
     7321 attgaagtta ttgtatatgt ggctaagtct cctattgctg ctgcaagaaa tactggaata
     7381 gcattatttc catctttttt ctttaaagcc ttaaatatta ggaatgatac gattggccct
     7441 attatcgcca ttgaaaaagc attagctcct aaagtagtta ttcctccatg tgctaataac
     7501 aatgcttgga atattaaaac tatagttcca agaacaaaca ttacgcttgg tccaaacatt
     7561 attgctccaa gacctacacc agtaggatgt gaacaacttc ctgttactga aggtattttt
     7621 agtgctgata atacaaacac aaatgctcca cataaagcta ataatacttt ctttttaggg
     7681 tcttgcttta ctattttacc tattgatttt aatccgaata agaaaaatgg tataaatata
     7741 actccccatg ctatagacca ttttactggt aagtaacctt ccattatatg cattgcattt
     7801 gatgtaactg gagttaaaat gattaacata agtgcagcta taacccctaa tttaatattc
     7861 tgtttcatct tagtatccct ctctcccttt ctaataatta aaacataata atacatgtct
     7921 gatttattta ataaaataaa aaagcctaac tcgatggtta ggcttctaat tttccacaat
     7981 ctaaatacaa acacataaaa caaacatatc tgtataatta ttataagaaa ctttctccat
     8041 ccccgaagaa attactttaa tattttaggc aggtctcctg acttagcttc atcctactcc
     8101 ttttccttcc catgagatat aaaaaatatc atcatagtgg ctaacaaaag tttcgtctgc
     8161 atcacagtag cgggggctgt aaaggaattt aacctttttc cctattaatc ttgcttaaag
     8221 aacctataat attatatatt taatttttaa attattctta aatcattttc tatataaatc
     8281 attgtatacc ttttctgtga aaatttctac attttttata aattttattc atttttatat
     8341 ttttatgtat ataaattctt ttttgtaagt ttattaattt ctaattatct tctttaaata
     8401 cattgaaact acatcagaaa atctagttat atctcttgaa tatataaaat catttccata
     8461 tattaatctt tcagcttcaa gttctgattc ttttcctgta aatactccta atactaatat
     8521 attttgcttt ctagcttttc tcacttcatt ggctgtatct ctcaaaccaa ctatacccct
     8581 ataagccttt tctcctctta atgttctctc actacttttt cctatcttta catcatttgg
     8641 tcttccatcg ctgagaacta tcaggatttt attttcttca tctctattta ttagaccact
     8701 acatatagat tttattgcca aaccatctct attattacca gcacaaaaat attcaaatat
     8761 attttcacta ttttttatac tatcatcata atctttaaat ctttttaata ttgtatagtc
     8821 taaaaaacta gaaaatccca tcactctatt tggtatgcca acttctgtta gagcatttgc
     8881 aattatgtaa gcttgaattg ccacatttcc ctgatttcta ctttgagagc cacttgcatc
     8941 caataatata tcaataacgt atttcccttt ttcattttct atatctttat aaaatatttt
     9001 attattatta cttctaccaa ctctccaagc tctattggct aatatagtac cacaatcaga
     9061 atatactcta cttttagcat tttcttctat taaaattctt gacagacttt cttttaatct
     9121 ctttatttgc tgtctataca ttctagcatg ttctctaaat tttcctaaat tattttcttt
     9181 ttgtcttgtt acatatttta gttgaaatac attattacac tcacttctaa gaactccatc
     9241 tgtaaagtgt attctacaac cttcatgaac atttctacaa ttttgtgtct caattttttt
     9301 aatttcacct ttactcaaat aagtttttcc ataataatgt tctatttttg aatatatctt
     9361 atttgcagtg tcttcatcaa catatataac tcggtctgct gaattgctac atttagaatc
     9421 atcaaaatcc cctacacctt ctacaagcat ggatgaagat attgaatcta tatcactttc
     9481 aataatattt tcttcttcat cactataaag ttcttcatac atgaaatcag caaatgtatc
     9541 aaaatttact tctacacttt ctacattatt ttcatcaata agactatttt cttctccatt
     9601 taatatgtat tcaaaataag ttaaatatat aacatctaat gcttttaaaa tctccataat
     9661 atcttgattg gtatctatat ttcttatatc attaactatt cttctagtca tactatctaa
     9721 tgctgggtgc ttgtccatac tataaagtac aaatgtgtat ttaattttat ccataatatt
     9781 atcattgtgt attttggtaa aacgtgaaac aatatcttta taagcattcc ttcttatgtc
     9841 ttctatccct ggcctgtctt taatgacctt ttcttcaact attgtattta atataacttg
     9901 aattagacct agtataacat ctttgttgta tccttttctt attctatttg taagatattt
     9961 tttaactata tcccaatcta catactttct tctagcacct gcaattattg cgaaatatag
    10021 acctatttct tttgaagagt aatctttttc tgatatatct atactttcat tgtaatcacc
    10081 agctattgtc catgataggt tattagctct attttcaaat tcataatcat catatatcca
    10141 tttcataatc tcacctatat taaatatgac ttattggaaa cacatctata ctctcccatt
    10201 tattaggtat tctagtttta attacatctc caaccatttc tttctcatat acatcaaaag
    10261 tctttcctgt aagtcccata ttaattgcaa gagttggttt taatcctctt cttatagtct
    10321 taagagatgc cataagacca cgtaaatcaa tagctttact agatatctct ccattttgag
    10381 acttcaattg taaatctaaa aatattcctg caaagtgtat taatttttct tcatcagcat
    10441 ctgaaaattc attttttaaa atcatcatta acttatcttc ttctatagga ggaatatcta
    10501 ttaccataaa tctagatacc agtgcttcat taagttcttt tgttcctgca tattcataat
    10561 tcatagtccc aataaatctt gttgctggat gtagattgac tctctcatac ccaggtacat
    10621 caattattct tctatagtct aaagctgaat gtaccacaac tatagcatca ttttttgcca
    10681 tattaatttc atcaaacacc ccaaaacctc cattaatagc acactcataa actgagcctc
    10741 ttctaagttt aacttcattg tctataaatg tatctgtacc tataagtgtt gaactgtctg
    10801 tatttatatg aaatgatgta ttccactgag gtctattaaa tatttcccct agattatcag
    10861 caagtaagtt ttttcctgtt gcctttggtc ccgataataa tatattttct tcttctaaaa
    10921 tagctgctat acacatagac aagatatctt taccataaaa ataagtttta gactttgtta
    10981 ctctgtattc taaatctttt tctaaaccat aataatttct aaaatacagt acatcttcaa
    11041 taagtttttc atctacccct tgcaccctta gattatctat tatatccata tttttacccc
    11101 ttttatataa atagtatttg tttcatttct tatcaccatt ttagcataaa aggatataag
    11161 ctaaaattga ttttttaatc tccccatttt aagtaaaacc atgcaccatt ttatcactac
    11221 aaaattaaga gtactactta ctgatatttc ttgattttgt tcgtctatac gtatataata
    11281 tatgctgata aattatgagg aaaggatgat tgaaatatgg atgcccagaa gtagcaaaaa
    11341 aatggggtat ttctgaaaga agagtacaaa aactatgtga agaaagtcgc ataccaggag
    11401 tttcaaaact cgggtatatg tggctgatac caaagaacgc agaaaagcct gttgatggta
    11461 gaacaaaaag aagaaaggaa gtacaatatg aatagcgttt tgattataga tgatgacaaa
    11521 gaactttgtg ctcttatgaa aaaatgtgtt gagcaagaaa atttatctgc tattactgca
    11581 cattgtggtg cagaaggtct acatttggtc gataaaaata gacacacact ctctcttgta
    11641 attttggaca taatgatgcc agatatagac ggttttcaag ttctgaaaaa aattagagaa
    11701 acaagtaata ttccagtaat tatgcttact gctaaaaatg acgaggatga taaagtttcc
    11761 ggactacgtt taggtgctga cgattaccta acaaaaccgt tcagcataaa cgaacttatg
    11821 gctcgtgtca attctcttat tcgtcggtat actatgttaa accctgcttt tataacagac
    11881 acagattgca taataataaa tggcatgatt attgacaaga caaaccgaat tgtttctgtc
    11941 aataatattc ctgttcaact tacaagcaaa gaatttgatt tacttgcttt tctggcttct
    12001 aataagggac gggtgtttac caaaaaacag atttatacac aagtatggga agaagaatat
    12061 gcttttgacg atagtaacat catgtctttc atcagtaaat tgagaaaaaa gattgaacca
    12121 gaccccaacc atccatttta tattttgaca gttcgtggtg tcggttatcg ttttaataag
    12181 gaggcttaac atgaatacaa gtgtctatct gcttttgata ttggttctta gcctgattat
    12241 tatagcgtac cttgtttctg tcctgctacg tgtccgaata caacttacac ttataaaaga
    12301 tgctttagag gatataaaaa atggaaacct taatcgacgt attttaacag atgaaaacga
    12361 cattacaaaa caaatttgct atgatattaa cgaaatagca atcaatagcc aatttcaact
    12421 tattcagcaa aaacaatcag aacaagccta caaacagcta atgacaagtc tctcccatga
    12481 tgtaaaaact ccacttgctt ctttggtcgg ttatttggaa gcagtagaaa gtaaaattgt
    12541 tgtaggagag gaaaaagacg agtatatcca tgttgcgtct aataaggctc attacttaaa
    12601 gaattttgta gaaaatctat ttgaatgggt aaaattggat tctaaggaac aagtttttca
    12661 ttttgatatt tttgacttga atgaattatc ccgtaatatt atatctgatt ggatacctgt
    12721 tttagaaagc agtcattttg aatatgaatt tgatatacca gaaatagagt acttcttacg
    12781 tatagacgca aatgcatata cccgtatcat taataaccta ttacaaaata ttattaccca
    12841 tagtagtggc aacaaaatga cattgagaat ttttgaaaac aaagagcaag ctcaaattat
    12901 aataacagat aatgggaaag gtatatcttc agacaatctc ccacatattt ttgaaaggtt
    12961 gtaccaatgc gaccattcac gagcttcaaa gggaaatggt ttaggcttgg cgattgcaaa
    13021 ggaacttatt aacgctcata agggaaatat taccgccaac agcactcccg gtatgggaac
    13081 agaatttaca atattgcttc ctaaagccct gtaaaagtac gaggctttct tactctaaaa
    13141 caagataaaa gcaagattat ggcaaggttt tggcaaggtt catgttttat aattctaatt
    13201 gtagttgatt ttgacgttgt atcaactatc ttttgtagaa acaaatttat taaaagtgag
    13261 gaaattatat atgaatgatt ttgtgattga aacaaagcaa cttacaaaaa tttatgggaa
    13321 tcaaacagta gttgacaaag tcaatctcca tgcaaaaaaa ggccgaatat atggtctgtt
    13381 aggacgcaac ggagctggga aaaccacaat tatgaaaatg attttaggat tgacttcaat
    13441 cacgtatggc gaggtagatg tatttggaga gaatattaag ggacgtgaaa aacaagtata
    13501 tccccgtatc ggtgcaatta tcgaaacgcc aggattttat cctaatctga caggaacgga
    13561 gaacttggag atttttgcaa aactgcgtgg tacagccgcc cctaattctg taaaaagagc
    13621 attggaaatt gtaggcttac cttataaaaa taaaaagctg tttagtgaat attcacttgg
    13681 catgaaacag cgacttggta ttgccaacgc tatcctgcat gacccagaac tgttagtttt
    13741 agatgagcca accaatggtc ttgaccctat tggtattgcg gagatgagaa agtttattag
    13801 ggacttgagc gttgagcatg gaaagacaat tcttatttcc agtcatattc tttcagaaat
    13861 ctcattgttg gctgatgata ttggaattat cgaccacggt gttcttttgg aagaaagtag
    13921 tatgagtgaa ctagaaaaga aaaacagtaa atatatcctg ctacaagttt cagatattcc
    13981 gaagacatca cttattttag agcgtcaatt taacacgaag gattattccg ttcaagatga
    14041 ctacacgtta cacctttata acactaatct ggatatgggt gaaatcaata aagcacttgt
    14101 aatgcagaat gtaactgtta ttagttctca actttgtaat gatactttag aggactactt
    14161 taaaaaaatc acaggaggag agggcattgc ttaaacttat tcaaacagaa tttcttaaac
    14221 tgcgtcgtag gaaacttatt tggctgatgt tgttgtctgc tctcattatg ccgtttttcg
    14281 cactactata cttcaattat tttggtaaaa caggtgttga gccaataaag ttttataaat
    14341 ggtctgcatt tggttataca ctttggatta ttttgcctgt tgttttgggt atattttgca
    14401 ccatgcttat acacgaagaa aaccagtatg atatgctcaa acagctttgg attgtaccta
    14461 ttagtaaaat gggatacttt tttagtaaat ttttcgttgt tttgatttac tctatttgtt
    14521 ttatgctgat tacagccgtt gcttctgtgt tatttagtgt actttctgga tatgtcgtat
    14581 ttagctgggc aagcatttta tatttgttga aaaaatgttt agaaattggt gtaatcactg
    14641 cttttgtaat gttgccgatt ttggcaatcg ctacatctca aaaaggatac attctcccaa
    14701 tttgtatcac attggtatat gccttttccg gttttgttat aatgacaata aatatgtatt
    14761 tacacccatt atccagtatg ggagttatta tcatgagaaa taaagacatt ccaggtctta
    14821 tattttcaca ggaaattaat gtcccattag catttctttg tatttgtatt tggagtattg
    14881 tatcagtatt gtttgcaaac actgcactag gaagaagaaa gtgaggtgta gataatgtgg
    14941 aaattacttt gggctgaatg tcaaaaaatt cgtcgttcaa aaattgtttg gattacagtt
    15001 tttgcatcca ttatgatagc agtcatagtt tttgcaggag ggcaggatgt atataatgac
    15061 ccagatttac attatggctt aaagagcgtt tatgacggtt cacggtatat agacaatgca
    15121 ggttggtata tggacgcagt acaaccttgg tcaacttttt ttgttcttcc tgctgtcatt
    15181 gccctattag gaagctatat tatttgtcgt gaagaagagg aggacactat taaatccctg
    15241 cgtcttattc ccataaatga aacaaaatta accatagcaa aaatgattat tacttttata
    15301 ttcagtatac ttctttattt gttactcttt actataacat ttttgactga atccgtttta
    15361 catttttccg atttatcgac aaaactggtt ttaagttgca tgaaagagta ttttcttgat
    15421 ggcataggtg tattctttgc aatttctccc attattgcct tggtatcgcg catgaaaaaa
    15481 ggatattggc ttgcattagt attcacagaa gtttattcta ttgctggact atttgcgggt
    15541 atgtcaaatg tcttacaaac cttttttcct attgcggcaa tatttaatat ttctggatac
    15601 tatataacta ctggagaaaa aattatgggg agtatcataa gtttattact ttgtgcctgc
    15661 ctttctgcat ttatacttaa agggctaaaa cacaatgaaa aaaattgaaa taggtatatc
    15721 aaaatgaaaa agataaaaaa actgattatt ctaattgtat tcttgtttct ttttggcatg
    15781 ttacactgtt atactgaatg gaaattcaac aataacccac ctaaaggggt aatagaaaga
    15841 ataaatgaat ggactgataa gattggactg gattagtaac ttatgttaat tatagtgaat
    15901 gtaatattag caagttattg tttcgtattt taatactata actttaaata tttggtttta
    15961 atcttccaaa cgaatataaa aaaactgtca cagaggcaac atatttttga atatttataa
    16021 agtggtagtt ttgattttca aagctgccgc cttttcttct atataagcaa acttatcctc
    16081 aacaaagtgt aaaacatggt acattttaag aaaaaagtac cacagacaca agcaataaaa
    16141 gaaacgccga gaacctacaa aaacgtagtg cttatgcaga tttacgacgc cttctatttt
    16201 ctcaaccgtc ttaatgacct tgtacaaaag aaatttttct aatatttttt ataatcttat
    16261 cttgtgatgt tttttatgta taaatgactt aataacaaat ccaataaaaa ttatggatat
    16321 tggtataatt agaacgagga atttataatc attataatgt gacattattc ttacccaact
    16381 ctcagaaaaa atatatccta tactgattaa tgaagtattc catatggtta ttcccacgat
    16441 agatgatatt acaaaagtta taatattttg acctgctata cctgctataa aagatatgta
    16501 tgttctacat aaagggatta atctacatac acaaacagaa atagaagagt atttgttaaa
    16561 ataatcttga gatgcaaata ttcctttctt tgcctttgga catatctcta ttattttatt
    16621 tatgatagat ttacctcccc aatttcccac tgtataacaa aatatcgaac caagtatacc
    16681 tgcaattata cttaaaatta aaattgtcag aaatccaaaa tgatttcttg cagcaattgc
    16741 tccacataaa ggtaaaacaa cttcgctagg taatggaaaa caagcatact caatcataat
    16801 taatacaaat acagagatta atccatattg taaaataaaa ctattgatta cagacactta
    16861 cttatctatc tcctttctta tttaaaggtt ttaagggtac atgttctaag gattctcacc
    16921 ctatatttaa agaatcaatc tctttaaact attatatgta tttacacaaa gcatttataa
    16981 catactttaa aaatagtacc ttaaaataag aaacttaata aataaaaaaa
//
LOCUS       DAYAOO010000090        16677 bp    DNA     linear   BCT 12-OCT-2024
DEFINITION  TPA_asm: Clostridioides difficile isolate ST8-SSI-h139-18
            SAMN40601845-rid21577343.denovo.091, whole genome shotgun sequence.
ACCESSION   DAYAOO010000090 DAYAOO010000000
VERSION     DAYAOO010000090.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN40601845
            Sequence Read Archive: SRR28438827
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 16677)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 16677)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-MAY-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-MAY-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002157583.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002157583.1
            Genome Coverage       :: 163x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/11/2024 16:19:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 4,038
            CDSs (total)                      :: 3,963
            Genes (coding)                    :: 3,930
            CDSs (with protein)               :: 3,930
            Genes (RNA)                       :: 75
            rRNAs                             :: 6, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 60
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 33
            CDSs (without protein)            :: 33
            Pseudo Genes (ambiguous residues) :: 0 of 33
            Pseudo Genes (frameshifted)       :: 7 of 33
            Pseudo Genes (incomplete)         :: 25 of 33
            Pseudo Genes (internal stop)      :: 11 of 33
            Pseudo Genes (multiple problems)  :: 8 of 33
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..16677
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN40601845-rid21577343.denovo.091"
                     /isolate="ST8-SSI-h139-18"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Denmark"
                     /collection_date="2018"
                     /collected_by="Statens Serum Institute"
     gene            19..891
                     /locus_tag="ACGI5H_003159"
     CDS             19..891
                     /locus_tag="ACGI5H_003159"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898679.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldose 1-epimerase family protein"
                     /protein_id="HFG9698851.1"
                     /translation="MNILQNENLIIESSSFGAELTKIFSKKYDKNILWDGNKKYWGRQ
                     SPILFPIVGKLFDNETIIEENLYSMTQHGFARDMDFEIVDKGDTFVTYKLTDNESTLK
                     KYPYSFELIINYTLNDNSIEVEWIVKNTDSKDIFFSIGGHPAFNLPFYEQNDFSKHYL
                     EFKSKNDVEKINLNGSFTDDIIPIGKLKNLQLNPEVFKNDALIYTNIDEVSICNNDGS
                     KYVTISMEDFPLVGIWTPYYSETNSTAPFLCIEPWYGLADSINSNKIYKDKKFINKLS
                     KGKVFTASYNINIH"
     gene            complement(1088..2275)
                     /locus_tag="ACGI5H_003160"
     CDS             complement(1088..2275)
                     /locus_tag="ACGI5H_003160"
                     /EC_number="4.4.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA];
                     GO_function: GO:0047804 - cysteine-S-conjugate beta-lyase
                     activity [Evidence IEA];
                     GO_process: GO:0009086 - methionine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MalY/PatB family protein"
                     /protein_id="HFG9698852.1"
                     /translation="MKYNFNKVLNRKEGNCRKWSNHVIKEKFGLNEDAIPMDLADIDF
                     ECAPAIKESILKRASVGDYSYTFIGDDFYDAIINWNKRRFDVYIEKDWIKLTFGTVST
                     LHYIVQAYTKEGEGVLINTPAYDPFAEAVVNNNRKLCCSSLKLDNNRYYLDLEDMENQ
                     MKYENIRLLIFCSPQNPSGRIWTKEELYQVSELCLKYNVILVSDEIHRDIIFKDYRFV
                     SLWNAHPEIYKNSIICVSPNKGFNLGGLKTSYVLIRDVKIRETLLERLKSNSITSPNV
                     FAIPAIVAAYNESEEWLDAMTSYVEENFEIVYDFFETNIPKAKVMKSDSSFLAWIDVR
                     EVFRNEEESKEFFRHANLTMVVGSYFVKDGDGFIRINVGCPRETLNEALNRIKKTYIS
                     MYC"
     gene            complement(2280..3350)
                     /locus_tag="ACGI5H_003161"
     CDS             complement(2280..3350)
                     /locus_tag="ACGI5H_003161"
                     /EC_number="3.4.11.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903771.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004177 - aminopeptidase activity
                     [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_function: GO:0070006 - metalloaminopeptidase activity
                     [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase P family protein"
                     /protein_id="HFG9698853.1"
                     /translation="MNNTMERLVSLIYKRGVDALLIKAKNTKRYIGALSGSGVYVLVT
                     KDKNYQILDGRYIDEADKKTTGFIKRIVSQGSYIPTIIELLKELNIKKLAIENQAMSI
                     QEYLSLKNEGFEINLITNELWKLRAIKSKEEIKLIKKACEITDEVFDEVISEIKKDMT
                     ELEVSALIQYHALKKGASGMSFETIVVSGERGAMPHGRPTNKKLKVNEAITIDFGVVY
                     QGYQSDMTRTISIGKPPKIIKEIYDVVLEAQLSAIESIKEGTRASDVDKVARKIIDKH
                     GFGEYFNHGLGHGIGLGDGEVPTLNPNSEDILVEGMVMSCEPGIYIPNVGGVRIEDDI
                     VIIDGKGVPLNKTSKEFIILGE"
     gene            complement(3360..4682)
                     /locus_tag="ACGI5H_003162"
     CDS             complement(3360..4682)
                     /locus_tag="ACGI5H_003162"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437786.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HFG9698854.1"
                     /translation="MFSKFEAFMNRVFMPLAHKVDNQRHLGSIKAGMVAMTPFTILGS
                     IFAILPALPNMLGENNPISKFILSNSAILDLPVSLSIGLIGLYACMCIAFNLGNYYKL
                     YIPGCVALSTFSFLFLVASFTPDGALEIGNLGAKGLFTGMIAGLGSVELYNFCNKKNI
                     TIKMPENVPDFVSRSFELIPTTIIVCGTFIVARFISLKVFGELPPQILTQFLSPLVGS
                     MDNPWSVLALNFAICTIFFFGIHSSVFSPITRPIMITFIAENIAAMQAGETIPHFFTA
                     GASSAFFGFTGCGISIGCVIACMLSKNASYKKIGRVSLFPALFGINEPILFGAPIILN
                     PIMFIPHVFGGAIIGTLPMFFMHWGWLAKPVFDPPYVGVFLEGFLTNGDWHSILANAL
                     QLVLAVLLYWPFFKIMERQQNNKKQKEETKNIFSKEEEGLLDDLGLDF"
     gene            complement(4714..5049)
                     /locus_tag="ACGI5H_003163"
     CDS             complement(4714..5049)
                     /locus_tag="ACGI5H_003163"
                     /EC_number="2.7.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421322.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HFG9698855.1"
                     /translation="MKILLCCAGGFSTNMLMQNMKKVVKESAKLNEKDFEFTAIPADS
                     IESEVDDWDIVLIGPQIAHKIDFLKGILEPKNKPFAVIDKDVYGKMDGATVMKLALIT
                     YKKHQLAQG"
     gene            complement(5146..5451)
                     /locus_tag="ACGI5H_003164"
     CDS             complement(5146..5451)
                     /locus_tag="ACGI5H_003164"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421329.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016740 - transferase activity [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose/cellobiose transporter subunit IIA"
                     /protein_id="HFG9698856.1"
                     /translation="MSTEVQIMELISTAGESKSKAFEALKKVKSKDFKGAKLLIEEAR
                     KIDIEAHRIQTELITQDLNEDVESPAMSLLMVHAQDHYMTSQLAKDLIEALIYCLDK"
     gene            complement(5466..6509)
                     /gene="ypdE"
                     /locus_tag="ACGI5H_003165"
     CDS             complement(5466..6509)
                     /gene="ypdE"
                     /locus_tag="ACGI5H_003165"
                     /EC_number="3.4.11.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891992.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase"
                     /protein_id="HFG9698857.1"
                     /translation="MNIEFFKRLSEADGIASNEEEVRHVLLEELKAYSDKIICDGLGS
                     IIFSKIKDESAPNVMICAHMDEVGFMVRSIDKLGMIHLITIGGVKPLAQFVQKVRITT
                     KEGKKIPAVINATYNNGKAENIYADIGAYTEEDVYNLGINVGDMVTYTTSFEEFTLPD
                     RLVGKAFDDRIGCFVMGEVLKELRKENLNCNIHFAATSSEEVGIRGAKTSTQLINPDI
                     VFVIDVACAKNEFVRDYTNKKQIDKGVMLMHRDRTLVPSRKMIDYVMEIADKNNIPLQ
                     HDMFESGGTDGGEAHLVNEGKPCVVTCVPVRYGHCAFSIVSNKDLENIIRLYTQLILN
                     FDEEQYKHIRNFI"
     gene            complement(6512..8413)
                     /locus_tag="ACGI5H_003166"
     CDS             complement(6512..8413)
                     /locus_tag="ACGI5H_003166"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891994.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antiterminator"
                     /protein_id="HFG9698858.1"
                     /translation="MRERIILETLKNSSGYLNIDYFADKLGVSTRTIRNEIKKIETIK
                     ECNGFKLEYKSKLGYILNIKDQDKFEHYLRNLPSDLVENPEQRLESIIVELLVNEGYK
                     TIEQLSKKFLVSSSQIKNDLKKIDEKIKDTELKLERKAHYGIKIEGSIKEIQSILVDS
                     YFRGNRNITEYRNKFIDNLKLANIRSTIKNVLNEHDLEANLTELEEILAQIIILYIRV
                     SMRVVGNASDLKLYTEDLIIDKLLDKIFRDKKYNLNYDEKYYLKELIKLKTKDKKATI
                     KNIDKNKLQDIMFEFFREIDKKYNSNFLEDKEFFNLFYLHIACLIERIKKNHKIINPF
                     SVKISQQYPTVFNLSIQFSKIIENEYHIKISQDEIGFIATHIAVPFEKREEANFNKKY
                     KIAIICSSGGGSAFLINLRLKEIFPNAEIRNFSLLEEKAVIEFAPDLIFSITNLLFEI
                     NAPVILINEILDELDYLDIKESVRFADHIGNISSPKQYILGLFDKNHFRCIKDKAKYK
                     DILDSMSKCIVDEGACSPTYPKDVWERESYLSTIYTNGVAIPHPIEMTGNKNIISVAL
                     IQTDIIYENRVPKIIFMISLIKGNLELHKQISKYLSKIMANKDMVDMLNKSQSYEEFM
                     YKLKIYLGG"
     gene            complement(8739..9590)
                     /locus_tag="ACGI5H_003167"
     CDS             complement(8739..9590)
                     /locus_tag="ACGI5H_003167"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892002.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tagatose-bisphosphate aldolase subunit GatY"
                     /protein_id="HFG9698859.1"
                     /translation="MALVTTTSMLKKAQDEGYAVGAFNVENMEMVIAVIEAAEELNSP
                     VILQTTPSTVKYAGLDYYLANAKVAAERVNIPVAMHLDHGSSFDLAMKALRSGYTSIM
                     IDGSHESFENNISISKSVVKACSPSLIPVEAELGKVGGKEDDLDGGNSNDYTNPKEAK
                     EFVDRTGISSLAIAIGTAHGLYKGEPKIDLDRLSEIKNVVSIPLVLHGGSGIHDDIIK
                     EAIKRGIAKVNYATELRIAYSKGVKKVLDEDSEVIDPKKYGLAGLQSVKDFVKEKIKV
                     CGSVNRV"
     gene            complement(9639..10802)
                     /locus_tag="ACGI5H_003168"
     CDS             complement(9639..10802)
                     /locus_tag="ACGI5H_003168"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898687.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0097367 - carbohydrate derivative binding
                     [Evidence IEA];
                     GO_process: GO:1901135 - carbohydrate derivative metabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="SIS domain-containing protein"
                     /protein_id="HFG9698860.1"
                     /translation="MFKLEEQKLKDLGAIITTNEIKQQPELWLETYEIYKSNKEKLSR
                     FIDTISNNHGQFRVIFTGAGTSAYIGNSILPYLKNKNDIRKYIFEAIPTTDIVSNPYD
                     YLKKDIPTLLISFARSGNSPESLAALNLGNKIVDNFYHLAITCNPEGELAKMTKNDEN
                     NYLLLMPSKSNDEGFAMTGSFSCMMLSAMLIFDSLEDDVEKSYINAIIEMGRNVIDRK
                     DEIHELINKDFDRVVYLGSGGLGGLTQEAQLKLLELTAGKISTVYDSPMGFRHGPKSF
                     IDENTLVFEFVSNCLYTRKYDLDVLEEIKRDKIAKFTCAVSVENENNFSGTKFEFKEK
                     YNKLPDVYLAMPYILFAQTIALFVSVKVGNKPDTPSATGTVNRVVKGVTIYEY"
     gene            11279..12196
                     /locus_tag="ACGI5H_003169"
     CDS             11279..12196
                     /locus_tag="ACGI5H_003169"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437799.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="HFG9698861.1"
                     /translation="MKNIKMGMIGLGSIAQKAYLPILTKSERFEFVGAFTPNKVKREK
                     VCSDYRIMPFDSIESLAKKCDCIFLHSSTETHYEIIKILLNLGVHVYVDKPLASTVSQ
                     GEELIELSTKKNLNLMVGFNRRFCPMYKEIKNNATEIVSINICKHGLNSLRNVRFDST
                     LIDDYIHVIDTALWLANEDVEISGEDLFLTDNKNLIFVSHKLKGKNFSINTSMHRDSG
                     TKLEQVEILSKGKIQRVKNLNVLEIEEGGNLTLKQSGAWVNILKQKGFEDISNHFIDC
                     IENNIKPAINGEECIKAQRLLEKIINSVK"
     gene            complement(12325..13254)
                     /gene="pfkB"
                     /locus_tag="ACGI5H_003170"
     CDS             complement(12325..13254)
                     /gene="pfkB"
                     /locus_tag="ACGI5H_003170"
                     /EC_number="2.7.1.56"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008662 - 1-phosphofructokinase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="1-phosphofructokinase"
                     /protein_id="HFG9698862.1"
                     /translation="MITVITFNPSIDRMYRVNNINIGEVQRVVSKNATAGGKGLNVAK
                     VCKILKENPLAMGFLGGFNGEFIKNELRKLDIQNKFTKIEQETRNCLNIIEDNKVSTE
                     FLEKGPIVEKSDLERFENDIEEVLKNTKILVASGSYCENMPIDYYEKIGNICRANNIK
                     FILDTSGEALKIALKSKPYLIKPNIDEIRHLLGMNIESREEIILSGKKLIEMGAENVC
                     ISLGKDGMVYLNEDNVYDVKVPVVKCINTVGSGDSTVAGFSVGILRGYKIENLLKFAN
                     ACGISNALNMETGFVDLGEIDKYQDLVEVKKLS"
     gene            13523..14248
                     /locus_tag="ACGI5H_003171"
     CDS             13523..14248
                     /locus_tag="ACGI5H_003171"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437811.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HFG9698863.1"
                     /translation="MIKRNDKRPIYDQLVEILRTKIENEMEPNDRMLSERKICDEYGV
                     SRTTVRLAMAELEHMGYIYKRHGKGTFVAALSQNSQNLMESYSFTDYMRTQGKKPGTK
                     VLSFEVVESTKYFSEKLGITPGEKMIKIMRLRLADDLPMMLERTYLPMKEFIGLTKEK
                     IEQKPLYEIFREDYGEIIKVADEEFSAGIISDKEAKLLEVPGDSPCLKLLRTTYNDDN
                     IVIEFTLSVARSDKFVYRVRHVR"
     gene            14331..15485
                     /gene="nagA"
                     /locus_tag="ACGI5H_003172"
     CDS             14331..15485
                     /gene="nagA"
                     /locus_tag="ACGI5H_003172"
                     /EC_number="3.5.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898693.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008448 - N-acetylglucosamine-6-phosphate
                     deacetylase activity [Evidence IEA];
                     GO_process: GO:0006044 - N-acetylglucosamine metabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylglucosamine-6-phosphate deacetylase"
                     /protein_id="HFG9698864.1"
                     /translation="MKSFIYADKFFMKHGIKEKGYLSIINGKFGEFQQERPNVTDNVI
                     DFSGKYIAPGLVDTHIHGLLGADVMDNTFEAINTISKGLLKYGVTSFLPTTLTDSVDT
                     LSDSVENISNSFNRVEGAKIQGIYLEGPFFTEKYKGAQNEKYFKDPDINILKLWQKKS
                     KNLIRKIAIAPERKGSIELTRYATKNNISVSLGHSSATFEQVKQVVNSGAKVFVHTYN
                     GMSPLNHREPGMVGAAMVLKDTYAELICDGHHVSPIAVKIMMDAKSSNNIALITDCMR
                     AGAMEDGKYTLGKFNVNVKNSVARLNSGSLAGSVLTMDKAVRNIVDWNISTLEDAIKM
                     ATYVPALSCNIDNVCGSIYQGMDADFIVTDNDFNIHETYINGICKYKVNK"
     gene            complement(16194..>16677)
                     /locus_tag="ACGI5H_003173"
     CDS             complement(16194..>16677)
                     /locus_tag="ACGI5H_003173"
                     /inference="COORDINATES: protein motif:HMM:NF015999.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0002161 - aminoacyl-tRNA editing activity
                     [Evidence IEA]"
                     /codon_start=2
                     /transl_table=11
                     /product="YbaK/EbsC family protein"
                     /protein_id="HFG9698865.1"
                     /translation="KGKYMYNNIKNILKENHITFEEYDHEPILSFEKAKEIREKLQYT
                     GVESKSLFIKDRSGNYYIFVTTEGKKLDPKTIKNVLGGKVSICSKEELTQKTQCLPGC
                     VSPFGYEKNISLVIDQDIFNHDKIIFSPGIPEKTFIITASGFKKVINNINNTTYKYIY
                     "
BASE COUNT         5636 a         2676 c         1969 g         6396 t
ORIGIN      
        1 taataaagga gattttaaat gaatatatta caaaatgaaa atttaattat cgaatcaagc
       61 agttttggtg ctgaactaac taaaatattt tctaaaaaat acgacaaaaa cattctttgg
      121 gatggtaata aaaaatattg gggtagacaa tcacctatat tgttccctat agtaggtaaa
      181 ctttttgata atgaaacaat aatagaagaa aatttatata gcatgactca acatgggttt
      241 gctagagata tggactttga gattgtagat aaaggagata catttgtaac ttataaatta
      301 acagataatg aatctacttt aaagaagtat ccatattctt ttgagctaat cataaactat
      361 acattaaatg ataatagtat tgaggtagaa tggattgtaa aaaatactga ttctaaagat
      421 atattctttt ctataggtgg acatcctgca ttcaaccttc ctttttacga acaaaatgat
      481 ttttctaaac actaccttga gtttaaaagt aaaaatgatg tagaaaaaat caatttaaat
      541 ggttctttta cagatgatat aatacctatt ggaaaattaa aaaacttaca gttaaatcca
      601 gaagtattca agaatgatgc tttgatatac accaacatag atgaagtgtc tatatgtaat
      661 aatgatggta gtaaatatgt aactatatct atggaagatt tccctctagt tggtatttgg
      721 actccttatt atagtgaaac taattctact gctccttttt tatgtataga accttggtat
      781 ggtcttgctg atagtataaa ttctaacaaa atttataaag ataagaagtt tattaataaa
      841 cttagtaaag gaaaagtttt tactgcttct tacaatataa atatacacta gataaaggtt
      901 agctaacccg ttcccaaaat aataaaatat ttttatataa gttaatataa gggtatgaaa
      961 taatattatt taatattcct caataatatt ccttaatcaa aaaatattac tggaatacaa
     1021 aattccagta atatttgata actaaataat gtgtttttat ataaaccata gatacttttt
     1081 ttatgattta acaatacata cttatatacg tttttttgat tctatttaga gcctcattta
     1141 atgtttctct aggacacccc acattaatac gaataaatcc atctccatct ttcacaaaat
     1201 aacttccaac taccatagtt aagtttgcat gtctaaaaaa ttctttagat tcttcttcat
     1261 ttctaaatac ttctcttaca tctatccagg ctaaaaaaga agagtctgac ttcatcactt
     1321 tagcttttgg tatattagtt tcaaagaaat cataaactat ttcaaaattc tcctctacat
     1381 aactagtcat agcatctagc cattcttcgc tttcattata tgctgcaact attgctggta
     1441 ttgcaaatac atttggagaa gttattgaat tactttttag cctttctaat aaagtctccc
     1501 taatttttac atctcttatt aatacatatg atgtttttaa tccacctaag ttgaagcctt
     1561 tattaggaga tacacagatt atactatttt tataaatttc tggatgagca ttccacaaag
     1621 atacaaatct ataatcttta aatattatat ctctatgaat ttcatcactt accaaaatta
     1681 cattatactt taaacataac tctgacactt gatatagttc ttcttttgtc catatacgac
     1741 ctgatggatt ttgtggacta cagaatataa gcaatcttat attctcgtat ttcatttgat
     1801 tttccatatc ctctaaatct aaataatatc tattgttatc taattttaat gagctacaac
     1861 acaactttct attattattt actacagcct ctgcaaaagg gtcataagca ggtgtattta
     1921 tcaatacacc ctctccttct ttagtatatg cttggactat ataatgaagg gttgaaacag
     1981 taccaaaagt taattttatc caatcctttt ctatatatac atcaaatctt cttttattcc
     2041 aatttataat agcatcatag aagtcatctc ctataaaagt ataactataa tctcctactg
     2101 atgctctttt taagatagat tcttttatag caggagcaca ctcaaaatcg atatcagcta
     2161 aatccatagg aattgcatct tcatttaagc caaatttttc tttaatcaca tggttgctcc
     2221 attttctaca atttccttct ttacgattta atactttatt aaaattatat ttcataattt
     2281 tactctccta atattataaa ctctttggat gtcttattga gtggaacacc ttttccatct
     2341 attataacaa tatcatcttc tattctaact ccccctacat ttggaatata aatacctggc
     2401 tcacaagaca ttaccattcc ttccactaat atatcttcac tatttggatt taaagtggga
     2461 acttcaccat ctccaagacc tataccatga cccagtccat gattaaaata ttcgccaaat
     2521 ccatgtttat ctataatttt tctagccact ttgtcaacat cacttgccct agttccttcc
     2581 tttattgact ctattgcaga taattgtgct tccaatacta catcatatat ctctttaata
     2641 attttaggag gtttgcctat agatattgta cgagtcatgt ctgattgata cccttgataa
     2701 acaacaccaa aatctattgt tatagcttca ttcactttca attttttgtt tgtaggtctt
     2761 ccatgtggca ttgcacctct ttctcctgat accactattg tttcaaaaga cattccactt
     2821 gcaccttttt ttaatgcatg atactgaatt agagctgata cttctagctc agtcatatct
     2881 tttttaattt cagaaataac ctcatcaaat acttcatctg taatctcaca agccttttta
     2941 ataagtttaa tttcttcttt agattttata gcccttagct tccataattc atttgttatt
     3001 aaattgattt caaaaccttc attttttagt gaaagatact cttgtatact catagcttgg
     3061 ttttctattg ctaacttttt tatatttaat tcttttaata actcaattat agttggtata
     3121 taagaacctt gagatacaat cctttttatg aaaccagtcg tttttttatc tgcttcatca
     3181 atatatctgc catctagaat ttgataattt ttatccttag taacaagcac atatacacca
     3241 ctacctgata aagctcctat atatctttta gtattttttg ctttaatcaa aagagcgtca
     3301 acacctcttt tatagattaa ggatactaat ctctccattg tattattcat aacaaaatat
     3361 tagaaatcca atcctaaatc atccaataag ccttcttctt ctttagagaa tatattctta
     3421 gtttcttctt tttgtttttt attattttgt tgacgttcca ttattttaaa gaatggccaa
     3481 tataataaaa ctgctaatac taattgcaat gcatttgcta atatagaatg ccaatctcca
     3541 ttagttaaaa atccttctaa gaatacccct acatatggag ggtcaaatac tggctttgct
     3601 aaccatcccc agtgcataaa aaacattggt agtgtaccta ttatagctcc accaaataca
     3661 tgtggtataa acattattgg atttaatatt atcggtgctc caaataatat tggttcattt
     3721 atcccaaata atgcagggaa taatgataca cgtccaatct tcttatagga agcatttttt
     3781 gataacatac atgcaattac acaacctata ctaattccac atcctgtaaa tccaaagaat
     3841 gcacttgaag ctcctgctgt aaagaaatga ggtattgttt ctccagcctg catagctgct
     3901 atgttttcag ctataaatgt aatcattata ggtctagtta taggactaaa tactgatgaa
     3961 tgtattccaa aaaagaatat agtacatata gcaaagttaa gtgcaagaac tgaccatggg
     4021 ttatccatac ttcctactaa tggagataaa aattgagtaa gtatctgtgg aggtaattct
     4081 ccaaatactt ttaatgaaat aaaacgagca actataaaag ttccacaaac tattatagta
     4141 gtaggtatta attcaaaaga cctagataca aaatcaggta cattttctgg catttttatt
     4201 gtgatattct tcttattaca aaaattatat aactccacag aaccaagccc tgctatcata
     4261 cctgtaaata gccctttagc tcctaaattt cctatttcta aagctccatc tggtgtaaat
     4321 gaggctacta ggaataaaaa agaaaaagtt gatagtgcaa cacaacctgg tatatataat
     4381 ttatagtagt tccccagatt aaaagcaata cacatacaag catataatcc tattaaacct
     4441 atggaaagac ttactggtaa atccaatatt gctgaattgc taagtatgaa tttgcttatt
     4501 ggattatttt ctccaagcat atttggaagt gctggaagta ttgcaaatat acttcctaat
     4561 attgtgaatg gtgtcatagc aaccatacca gcctttatag aaccaaggtg acgttgattg
     4621 tcaaccttat gagctaaagg cataaatact ctattcataa atgcttcaaa ttttgaaaac
     4681 atatctaatc tcccttttcc ctcattattt ttattatcct tgagctaatt gatgtttctt
     4741 ataagttatt aatgccaact tcataactgt agctccatcc atttttccat atacatcttt
     4801 atctattact gcaaaaggct tattttttgg ctctaatatt ccttttaaga agtctatttt
     4861 gtgagctatt tgaggaccta taagtactat atcccaatca tcaacttcac tttctattga
     4921 atctgctggt atagctgtaa actcaaaatc tttttcattg agtttagcac tctcttttac
     4981 cacctttttc atattttgca ttaacatatt agtagaaaat ccacctgcac aacataataa
     5041 tattttcata ataattcctc ctaaagtttg tatttttatt atctcttaaa agcatctaaa
     5101 cttttaaaag aatttttaca taaataatct atttctatat tacaattact tatcaagaca
     5161 atatatcaaa gcctctatca agtcttttgc tagctgagaa gtcatatagt ggtcttgagc
     5221 atgtaccatt aaaagactca ttgctggact ttcaacatct tcatttaaat cttgagttat
     5281 taattctgtt tgtatcctgt gagcttcaat atctatttta cgagcctcct ctattaacaa
     5341 ttttgctcct ttaaaatctt ttgacttcac tttttttaaa gcctcaaaag ctttcgattt
     5401 actctctcct gcagttgata taagttccat tatttgtact tctgttgaca ttttcttatt
     5461 ctcctttaga taaaatttct tatatgttta tattgttctt catcaaaatt taaaattaac
     5521 tgtgtataca atcttataat gttctccaaa tctttattac ttactattga aaatgcacaa
     5581 tgaccatatc taactggtac acaagttact acacaaggtt tcccttcatt tacgagatgt
     5641 gcttctcctc catcagtccc acctgattca aacatatcat gttgaagtgg tatattattt
     5701 ttatcagcaa tttccattac ataatctatc atttttctac tagggactag agtcctatct
     5761 ctatgcatta gcattacacc tttatcaatt tgtttcttat ttgtatagtc tctcacaaac
     5821 tcatttttag cacatgctac atctattaca aatactatat ctggatttat taactgtgtt
     5881 gatgtctttg ctccccttat tccaacctct tcactacttg tagccgcaaa gtgaatatta
     5941 caatttagat tttctttcct aagttctttt aaaacttctc ccatcacaaa acatcctatc
     6001 ctatcatcaa aagcctttcc cactaatcgg tctggtaaag taaattcctc aaagcttgtt
     6061 gtatatgtta ccatatcccc aacattaatc cctaggttat atacatcttc ttctgtatat
     6121 gctccaatat ctgcatatat attttcagcc ttaccattat tatatgtagc atttatgaca
     6181 gcggggattt tcttcccttc ttttgttgta attctaactt tttgtacaaa ctgtgcaaga
     6241 ggttttactc ctcctattgt tattaagtga atcataccaa gtttgtctat acttctcacc
     6301 ataaatccaa cttcatccat atgagcacaa atcattacgt ttggtgcact ctcatctttt
     6361 attttagaaa agatgatact ccctagccca tcacagataa ttttatcact ataagctttt
     6421 agttcttcca ataaaacatg tctaacctct tcttcattag atgctatacc atctgcttct
     6481 gacaacctct taaaaaactc tatattcatg tctaacctcc cagatagatt tttaacttat
     6541 acataaactc ttcataagat tgtgacttat ttagcatgtc taccatatcc ttatttgcca
     6601 taatcttact taaatattta gatatttgct tatgaagttc taaatttccc tttattaatg
     6661 aaatcatgaa aataatttta ggcaccctat tttcataaat aatatcagtt tgtatcaaag
     6721 ctactgatat tatatttttg tttcctgtca tctcgattgg atgaggtata gccaccccat
     6781 ttgtataaat agtactcaaa taactttctc tttcccatac atctttggga taggttggag
     6841 aacaagctcc ctcgtcaact atacattttg acatactatc aaggatatcc ttatacttag
     6901 ctttatcttt tatacaccta aagtgattct tatcaaatag acctaatata tattgttttg
     6961 ggcttgatat atttcctata tggtctgcaa atctaacact ttctttaata tctaaataat
     7021 ccaattcgtc taaaatttca tttataagta taactggagc atttatttca aataaaagat
     7081 ttgttattga aaaaatcaaa tctggtgcaa attctattac agctttttct tctagtaatg
     7141 aaaaatttct tatctcagca tttggaaaaa tttctttaag tcttaaattt atcaaaaatg
     7201 cactacctcc accagaagag catattattg ctattttata ttttttatta aaattagctt
     7261 cttctctctt ttcaaaagga acagcaatgt gagtagctat aaaccctatt tcatcttgac
     7321 ttatttttat atgatactca ttttctatga tttttgaaaa ttgaatagat aaattaaaaa
     7381 cagttggata ctgttgactt attttaactg aaaaaggatt tattatcttg tggttcttct
     7441 ttatacgttc tattaaacat gcaatatgta agtaaaataa gttaaaaaac tctttatctt
     7501 ctaaaaaatt agagttatat tttttatcta tctctctaaa aaattcgaac ataatatctt
     7561 gaagtttatt cttatcaata ttctttatag tggctttctt atctttagtc tttagtttta
     7621 taagctcctt taaataatac ttttcatcat aattaaggtt atatttttta tctctaaaaa
     7681 ttttatctaa taatttatct ataattaaat cttctgtata taattttaaa tcgctagcat
     7741 ttcccactac tctcatacta actcttatat acaatataat aatttgtgct aatatttcct
     7801 caagttctgt taaatttgct tctaaatcat gttcattaag tacatttttt attgtacttc
     7861 taatattagc taattttaaa ttatctataa acttattcct gtactctgtt atatttctat
     7921 tccctctaaa ataactatcc accaatatac tttgaatttc ttttatagaa ccttctattt
     7981 taattccata atgagccttt cgctctagtt ttaattctgt atcctttatc ttttcatcta
     8041 tcttttttaa atcatttttt atttgggatg aacttactag aaatttttta cttaactgtt
     8101 ctatagtttt ataaccttca tttactaaaa gctctactat tatagactcc aaccgttgtt
     8161 ctggattttc aactaaatct gagggtaagt ttcttagata atgctcgaat ttatcttggt
     8221 ctttaatatt tagaatatat cctaatttag acttatattc taatttaaaa ccattacatt
     8281 cttttatagt ttctatcttt tttatttcat ttctgatagt tcgagtagat acccccaact
     8341 tatctgcaaa ataatctatg tttagataac cactactatt ttttaatgtt tcaagaataa
     8401 tgcgttctct catatcccca cctccctcag tgttattatt gtgtttttta aagtggtata
     8461 aaaaatattt tttataaaaa caaccttttc tttttattta agaattttat atcctagtat
     8521 attttaattc cacaatttaa tataaatatt ttataataat aaaatatata gttcaatttt
     8581 tagtatattt taattatata tgtaatactt taccaataaa agctgatatt tttcatcaat
     8641 taaatgaaaa aaatacacca tttacatata attaatataa atttttcata taataaatat
     8701 cctaaactta tctaaaataa atttaggata ttttattttt atactctatt tacagaccca
     8761 cacactttaa tcttttcttt cacaaaatcc tttactgatt gaagccctgc taatccatac
     8821 tttttagggt ctataacctc agaatcttca tctaaaactt ttttaacccc tttactatat
     8881 gcaattctta attcagttgc atagttaact tttgcaatac ctctttttat agcttctttt
     8941 ataatatcat catgtattcc tgaacctcca tgcaatacta aaggtattga aactacattt
     9001 ttaatttctg ataacctatc taaatctatt ttaggttcac ccttatacaa tccatgtgca
     9061 gtacctatag caatagccaa tgaagatatt cctgttctat cgacaaactc ttttgcctct
     9121 tttggatttg tataatcatt actattcccg ccatctaaat catcttcttt tccaccaact
     9181 ttcccaagtt ctgcttccac tggtataaga gaaggactac atgcttttac tactgattta
     9241 gatatagata tattattttc aaagctttca tgagaaccat ctatcattat tgatgtatat
     9301 ccacttctta aagctttcat tgcaaggtca aaacttgaac catggtccag atgcattgct
     9361 acaggtatat ttactctttc tgcagcaacc tttgcatttg ctagataata atcaagacct
     9421 gcatatttta cagtagatgg agtagtttgt aatattactg gagaatttaa ctcctcagca
     9481 gcttctataa cagcaattac catttccata ttttctacat taaatgctcc tactgcatac
     9541 ccttcatctt gtgccttttt aagcattgat gttgttgtta ctaatgccac attgataccc
     9601 tcccaaatta tttagttata atattttaat cttatctttt aatattcata tattgttaca
     9661 ccttttacta ctcgatttac tgttcctgta gctgatggag tatctggctt atttccaacc
     9721 tttactgata caaacaatgc tatagtttgt gcaaacaata tgtatggcat tgcaagatac
     9781 acatctggta atttattata cttttcttta aactcaaact ttgttcctga gaagttattt
     9841 tcattttcta ctgacactgc acaagtgaat ttagcaattt tatccctttt tatctcctct
     9901 aaaacatcta aatcatattt tcttgtatat aaacagttag atacaaattc aaatacaagt
     9961 gtattttcat caataaatga ttttggtccg tgtctaaacc ccataggaga atcatacact
    10021 gtagatattt ttcctgctgt aagttctaaa agttttagtt gtgcttcttg tgtcaaacca
    10081 cctaatcctc ctgaacctaa atatacaact ctatcaaaat ctttatttat taactcatgt
    10141 atttcatctt ttctatctat aacatttctt cccatttcaa ttattgcatt tatatatgac
    10201 ttttctacat catcttctaa actatcgaat attaacatag cagataacat catacacgaa
    10261 aaacttcctg tcatggcaaa gccttcatca tttgattttg atggcattaa taacaagtaa
    10321 ttattttcgt cgtttttagt catcttagcc agttctcctt ctggattaca agttatagct
    10381 aaatgataaa aattatctac aatcttattc cctaaattta aagctgctaa actttcagga
    10441 ctatttccac ttcttgcaaa tgaaattaat aatgttggta tatctttttt taagtaatca
    10501 tatgggtttg aaactatatc cgtagtaggt attgcttcaa atatgtattt tcttatgtca
    10561 tttttatttt taaggtaagg aagtattgaa tttcctatgt aagctgaagt tccagcacct
    10621 gtaaatataa ctctaaactg cccatgatta ttacttattg tatctatgaa tctacttaat
    10681 ttttctttgt tagatttata tatttcataa gtttctaacc ataattcagg ctgttgtttt
    10741 atttcattag ttgttattat tgcacctaaa tcttttagtt tttgttcttc taatttaaac
    10801 attttcattc tcctttcata cttgtaacgt ttacatttgg taatgaggtt ataaccactt
    10861 taaactataa aaaaatatac tcttttataa ttttttgctt agatttttta gtactactta
    10921 aactcactat aaaatataca ctatagattt taattaattt tatagtttat ctttaaaaat
    10981 ttaataaaat catactctat atactttagt atttttattt tacgataaaa gcttgttcag
    11041 accaaagtgg taattaccac taatccaaat ataaattaat ttgaattttt tgtcaataca
    11101 taaaatattt atatcaatca attttatgga tatcctacaa aattacttta tcaatatttc
    11161 ttatttcgct aatttactta tataagcttt aaatttattt tttgatacaa agtttacaaa
    11221 tttatgtgtc tgaattataa tcaattctgt aaatataaaa accttaggag aaagtattat
    11281 gaaaaatata aaaatgggaa tgataggtct tggctccata gctcaaaagg catatttacc
    11341 tatattaact aagtctgaga gatttgagtt tgtaggagct tttactccaa ataaagttaa
    11401 aagggaaaaa gtctgtagtg attatagaat catgccattc gattctattg aatccctagc
    11461 taaaaaatgt gattgtattt ttctacatag ctctacagaa acacactacg aaattataaa
    11521 aatattatta aatttaggtg ttcatgtata tgtagacaaa cctcttgctt caacagtaag
    11581 tcaaggagaa gaacttatcg agttaagtac gaaaaaaaac ttaaatttaa tggttggatt
    11641 caaccgtaga ttctgtccta tgtacaaaga aattaaaaat aatgctacag aaattgtatc
    11701 tatcaatata tgtaaacatg gattaaattc cttaagaaat gttagattcg acagtactct
    11761 tatagatgac tatatacatg ttattgacac tgctttatgg ttagcaaatg aagatgttga
    11821 aattagtgga gaggatttat ttttaacaga caataagaat cttatatttg taagtcataa
    11881 acttaaaggt aaaaatttct ctataaacac ctctatgcat agagattctg gaacaaagtt
    11941 agaacaagtt gaaattcttt caaagggtaa gattcaaaga gttaagaatc ttaatgtact
    12001 ggaaatagaa gaaggtggaa acctaacttt aaagcaaagt ggtgcatggg taaatatatt
    12061 aaaacaaaag ggttttgagg atatatcaaa tcattttatt gattgtatag aaaataatat
    12121 aaaaccagct attaatggag aagagtgtat caaagctcaa agattactag agaaaattat
    12181 aaattcagta aaatagatat ttattataaa aataggttaa aaatgaattt ttctaaccta
    12241 tttttatata agactatatc ttttatatta aaattaaaat ctattacaac aacattaaat
    12301 ttattatatt cccattaaat gtatttaact taactttttt acttcaacta aatcttgata
    12361 tttatcaatt tctcccaaat ctacaaatcc agtttccata tttaaagcat tacttatacc
    12421 acaagcattt gcaaatttaa gtaaattttc tattttataa ccccttaaaa tacctacact
    12481 aaatccagcc actgtgctat ctccactacc tacagtattt atacacttta caactggtac
    12541 ttttacatca tatacattat cttcgtttaa atacaccata ccatcttttc ctaaagatat
    12601 acatacattc tctgcaccca tttcaataag tttttttcct gacaagataa tttcctctct
    12661 tgattctata ttcattccta ataaatgtct tatttcatct atatttggtt ttattaaata
    12721 tggttttgat tttaaagcta tttttaatgc ttctcctgat gtatctaata taaactttat
    12781 attatttgct ctacatatat ttcctatctt ttcataatag tctatcggca tattctcaca
    12841 ataactacca gaagctacca gtattttagt attttttagt acttcctcta tatcattttc
    12901 aaatctctct aaatcgcttt tttctactat tggtcctttt tctaaaaatt ctgtactaac
    12961 tttattgtcc tcaattatgt ttaagcaatt tctagtttcc tgctctattt ttgtaaattt
    13021 attttgtata tctagttttc taagttcatt ttttataaat tctccattaa atccgcctag
    13081 aaatcccata gctaaaggat tttcttttaa aattttacat accttagcta cgtttaatcc
    13141 tttacctcca gcagttgcat tcttacttac taccctttgc acctcaccta tgtttatatt
    13201 attcactcta tacattctat ctatagatgg gttgaatgtt attactgtaa tcatactaga
    13261 ttctcctcat tattaatttt tacttttcta aacaataaat taatctgtaa aataaaaaat
    13321 acctcatcta taatataccc aaagtggtta ttaccaattt gaatataaat tattttactt
    13381 gttttgtcaa tgtaccataa ttttataata aattaataac cttacttatt gaattttgat
    13441 taaactttat tcattgacat aaataattct atattctata atcaaattgt ggtaataacc
    13501 acttagaaag gactatattt ttatgataaa aagaaatgat aaaagaccaa tatatgacca
    13561 gcttgttgag atattaagaa ctaagattga aaatgagatg gaaccaaacg atagaatgct
    13621 ttccgaaaga aaaatttgtg atgaatatgg agtaagtaga accacagtta gactagctat
    13681 ggctgagttg gaacatatgg ggtatatata caaaagacat ggaaaaggaa cttttgttgc
    13741 tgcactaagt caaaattctc aaaacttaat ggaaagttat agttttacag attatatgag
    13801 aacacaagga aaaaagccag gtacaaaggt attatcattt gaggtagtag aaagtacaaa
    13861 gtatttctct gaaaaattag gtataactcc tggtgaaaaa atgataaaaa taatgcgttt
    13921 aagacttgct gatgaccttc ctatgatgct tgaaagaaca tatcttccta tgaaagaatt
    13981 tataggattg acaaaagaaa aaatcgaaca aaaaccttta tatgaaatat ttagagaaga
    14041 ttatggcgag attattaaag ttgctgatga agaattttca gctggaataa tctctgataa
    14101 ggaagctaag ttattggaag taccaggaga ttcaccttgt ctgaaattac ttcgtaccac
    14161 atataatgat gacaatatag ttattgaatt tactttgagt gttgctagaa gcgataaatt
    14221 tgtatataga gtaagacatg taagatagta agttaaataa ctttcaagaa aatagaatga
    14281 tattataaac gtcaatgcca caatgatagt ataattataa ggaggttatt ttgaaaagtt
    14341 ttatttatgc agataaattt tttatgaaac atggaatcaa agaaaaaggt taccttagta
    14401 taattaatgg caaattcggt gaatttcaac aagaaagacc taatgttact gataatgtta
    14461 tagatttttc aggtaaatat attgctcctg gcttagttga tactcacatt cacggtcttt
    14521 taggtgcaga tgtcatggac aatacatttg aagcaataaa cacaatttca aaaggcttat
    14581 taaaatatgg agtaacatct ttcctaccta caactttaac tgattctgta gatacactaa
    14641 gtgattctgt agaaaatata agcaatagct tcaatcgagt tgagggtgca aaaatacaag
    14701 gtatttattt agaaggtcca ttttttacag aaaaatataa gggcgctcaa aatgaaaaat
    14761 attttaaaga ccctgacatc aatatattaa aattatggca aaaaaaatcg aaaaatttaa
    14821 taagaaaaat agcaattgct ccagaacgta aaggttcaat agaattaaca agatatgcaa
    14881 ctaaaaataa tatatcagtt tctcttggtc atagttcagc tacatttgag caagttaaac
    14941 aagtcgttaa ttcaggtgct aaagtgtttg tacatacata taatgggatg agtcctttaa
    15001 atcatagaga acctggaatg gttggggctg ctatggtact aaaagatact tatgctgaat
    15061 taatttgtga tggtcatcat gtaagcccaa tagctgttaa aataatgatg gatgcgaagt
    15121 ctagtaataa catagcttta attacagatt gtatgagagc tggtgctatg gaggatggaa
    15181 aatatactct tggtaagttt aatgtaaatg taaaaaatag tgttgcaaga ttaaatagtg
    15241 ggagtttagc tggaagtgta ttaactatgg acaaggctgt gagaaatata gttgattgga
    15301 acatatcaac tttagaagat gcaataaaaa tggctacata tgtccctgct ttaagttgta
    15361 atattgataa tgtctgtggc tctatatatc aaggtatgga tgcagacttt atagtaacag
    15421 ataatgactt taatatacac gaaacttata taaatggtat ctgtaagtac aaagttaata
    15481 aataggttca atataaggtt atggaggctg tctaaaaaga gtctggaaat atttaaagtt
    15541 atttctccaa aatctgattt aacactttta tttccatatc gttaataaac tattgcgata
    15601 gaggttattt taaacaaata tatattataa gtatttttgt gataatattt tcgataatat
    15661 gtacatttaa agtaactttt ctattattat ttgtaagttt ttatcttgag caaacatata
    15721 aatttttaat aaagcatgag ataaacccta tatttcaatt actaatgatg agattttgat
    15781 tgataacaga tatattttca aatgtaaaaa tactaaaaat catatcaatt ttaaagatat
    15841 tgtaggtgta aataaacaag ataatactat agaaattttt acaaatgaaa gcacttattg
    15901 tatatatcta aaagttttaa gcattgagag cgaagaatat ctaatagata gactaaaatc
    15961 attttgttga ttttatatat tttatgttaa atataaagca gagtagttaa aactaccctg
    16021 cttttgtaat taaaatttaa aaataataac tcataataca ttgaatttga gcttaacagt
    16081 aactattgta ataatagtat caatcttttg tgttgaatat aatttattta cactatagtt
    16141 aagcatgatt tctaatgtta ttttctctaa tttacaatta tgattaaaat tcattaatat
    16201 atatatttat aagttgtatt gtttatattg tttattactt ttttaaatcc actagctgta
    16261 ataataaatg tcttttctgg tatccctggt gaaaagatta ttttatcatg gttaaatata
    16321 tcttgatcta ttacaagaga gatatttttc tcatatccaa aaggagatac acatccaggc
    16381 aaacattgtg ttttttgtgt taattcttct tttgaacata tagatacttt tccacctaaa
    16441 acatttttta tagtttttgg atctaatttt tttccttctg tggttacaaa tatatagtaa
    16501 tttccagatc tatcttttat aaataaactt ttactttcta ctccagtata ttgtaatttt
    16561 tctcttattt ctttagcttt ttcaaatgat aaaataggtt catggtcata ttcttcaaac
    16621 gttatatgat tttcttttaa aatatttttg atattgttgt acatatattt tcctttc
//
LOCUS       DAYAOO010000091        16216 bp    DNA     linear   BCT 12-OCT-2024
DEFINITION  TPA_asm: Clostridioides difficile isolate ST8-SSI-h139-18
            SAMN40601845-rid21577343.denovo.092, whole genome shotgun sequence.
ACCESSION   DAYAOO010000091 DAYAOO010000000
VERSION     DAYAOO010000091.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN40601845
            Sequence Read Archive: SRR28438827
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 16216)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 16216)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-MAY-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-MAY-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002157583.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002157583.1
            Genome Coverage       :: 163x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/11/2024 16:19:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 4,038
            CDSs (total)                      :: 3,963
            Genes (coding)                    :: 3,930
            CDSs (with protein)               :: 3,930
            Genes (RNA)                       :: 75
            rRNAs                             :: 6, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 60
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 33
            CDSs (without protein)            :: 33
            Pseudo Genes (ambiguous residues) :: 0 of 33
            Pseudo Genes (frameshifted)       :: 7 of 33
            Pseudo Genes (incomplete)         :: 25 of 33
            Pseudo Genes (internal stop)      :: 11 of 33
            Pseudo Genes (multiple problems)  :: 8 of 33
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..16216
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN40601845-rid21577343.denovo.092"
                     /isolate="ST8-SSI-h139-18"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Denmark"
                     /collection_date="2018"
                     /collected_by="Statens Serum Institute"
     gene            245..1693
                     /locus_tag="ACGI5H_003174"
     CDS             245..1693
                     /locus_tag="ACGI5H_003174"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728826.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004553 - hydrolase activity, hydrolyzing
                     O-glycosyl compounds [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="family 1 glycosylhydrolase"
                     /protein_id="HFG9698866.1"
                     /translation="MKLGKDFLWGGAISANQSEGFYLDGGKGLSQFDKLPLNDKRLKN
                     VCLDEDNILNENNQYYPSHIGIKFCENYKEDIAMLAEIGFKCFRFSISWSRIFPTGEE
                     SEPNEKGLQLYDNIIKELKKYNIEPLITISHFDIPYSLVEKYSGWADRRVVNLYVKYA
                     EILMKRYKDDVKYWIPFNEMNMIMHIPYIGAGLTFIADENQLQKKYQAAHHQLLANAK
                     TIEIGRYINKEFKFGCMLAAGKTYPYTCKPEDVFATLEHERHNLFFSDVQVRGVYPSF
                     MSYYLKSNQIKLIIKEEDLSTLKDNTVDFVSFSYYSSACSSARAEGLEKSKANGPETI
                     KNPYLPKSNSVWQNDPVGLRITMNQLYERYQLPLFIVENGLGTQDIVNEDGKIIDDYR
                     IDYMKEHIKNMILGVNEDGIELIGYLMWGCIDVTSVSEGKMTKRYGIIHVDSDDYGRG
                     SFKRTKKQSAFWYKKVIETDGEILFNDMETHA"
     gene            1719..4109
                     /locus_tag="ACGI5H_003175"
     CDS             1719..4109
                     /locus_tag="ACGI5H_003175"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893828.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyl hydrolase family 65 protein"
                     /protein_id="HFG9698867.1"
                     /translation="MSLIFTTKDQLVELGFSKDTIKSNETLFTLANGHLGVRGNIEES
                     DFNNEYVDNMGTYVNGFYEESPITYGESAYGYAKQNQTICKLPNAHIVNFSIEGDCFD
                     LSKGITSEHTRILDLNEGILKRSFIWENSRGRKVKVSIERLVSQDIEELMMISYTITP
                     LNFNGKIKFKNKMENSMEKFNCEKVDDPRVASINKKQFKINVKKYNNKYFMNLVTERS
                     RLGLWCGFDSYITCGNITNETYNVSDECIEREIEVYAKKDERLNLEIVVGYSRVYSDL
                     NLNEERLKSLECLESLKCLESEAHLKSLELVLREACNIGFDKVKNIQRKKMNEFWTTS
                     DVEIEGDKTLQLGIKTNLFHIYQSAGRDGKTNISAKGLTGDGYEGHYFWDTEMYILPF
                     FIYTQPSIARALLDYRYSILDASRERARELGINKGCLYSWRTINGNECSAYYPAGTAQ
                     FHINADIAYGVRTYFEATNDEEFMMQNGLEILIETSRFWVEFGDYIESKNNKFCINGV
                     TGPDEYTAIVNNNYYTNLMAKYNLIYAVQMVDKFKHNLFSNEVFRKVKLQEYEVKNWI
                     NAAQNMYLPYDEEKKISKQDDSFLEKSVWDFKNTPKEKYPLLLHYHPLTIYRYQVNKQ
                     ADTVLSALLFPDEFSLEQKKRDFEYYEKITTHDSSLSRSIFGMMASEIGNHEKAYNYF
                     MDTALMDINNLQKNTSDGIHAANMGGTWMSLVYGFAGMKIKNDKLSFEPRIPKHWKNI
                     KFNILFRDNLVFVNIEEYKSYYKLIKGRNITILHDNKEIKLSKNIIEVNNCFKGSN"
     gene            4111..4782
                     /gene="pgmB"
                     /locus_tag="ACGI5H_003176"
     CDS             4111..4782
                     /gene="pgmB"
                     /locus_tag="ACGI5H_003176"
                     /EC_number="5.4.2.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891494.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000287 - magnesium ion binding [Evidence
                     IEA];
                     GO_function: GO:0008801 - beta-phosphoglucomutase activity
                     [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="beta-phosphoglucomutase"
                     /protein_id="HFG9698868.1"
                     /translation="MKAVLFDLDGVITDTAKYHFEAWHEIAKSLDIEIDETFNEKLKG
                     INREESLDKILLSANKVDSYTKEEKLKVCEEKNNIYIKLINSLTYKDILPGINELIKE
                     LKKNNVKLGIASASKNAPRILESLGVKDEFDCIVNPSLLKRGKPYPDIFIEGSKMLNL
                     KQYDCVGIEDSYSGIKAINAANMTSIGVGKKEVLGKCDHIVEDTSLLNYNTLLQAWSK
                     KINLD"
     gene            4821..6191
                     /locus_tag="ACGI5H_003177"
     CDS             4821..6191
                     /locus_tag="ACGI5H_003177"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003440058.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HFG9698869.1"
                     /translation="MKNKYEDVAQLIIDGLGGKDNIIDLTHCMTRLRFILKDEKKVNA
                     DKLKSIDKVVGVNSTSTQYQVIIGNEVGVVFNAIINKGINTTGDIKSDIKNKNKKNSI
                     LNNIIDTITGCMTPMIPALTASGMIKVILSLCTTFNWLSSNSSTYRVLDIIGDVAFYF
                     MPIILAINAAKKFNVNTSIAVIVVGVFLHPNFSAWVSSGDPISFIGVPIQGVIYAASV
                     IPALLTVWMMSYIENFIDKLTPSMLKTILNPTLVLLISAPIALIVIGPIGNFLGEGLA
                     SIINLLQGRLGFIMVCLLAAAMPFIVMTGMHHALTPIFISAFATTGQESLILISQVCA
                     NLAQGGATLAVALRSKDSKMKQLASAAWISAIMGITEPALYGVTLKLKKPAMLASIGA
                     GIAGLFAGITHVTLYVPQNSIMAVLGLSGEKGISNIVNGLIVIFIALVAPFIMTYVFG
                     VEKNVK"
     gene            6538..7380
                     /gene="licT"
                     /locus_tag="ACGI5H_003178"
     CDS             6538..7380
                     /gene="licT"
                     /locus_tag="ACGI5H_003178"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898228.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="BglG family transcription antiterminator LicT"
                     /protein_id="HFG9698870.1"
                     /translation="MIINKILNNNVVITLDDNDEEVIVMGKGIGYQKSKGNLIDKTKV
                     NKVFRISNKEISNKLQELLNNIPIEHMKLSSEIIEYAQIKLNKKLNESIYISLSDHTY
                     SAIQRMKEGINVKNAILWEIKRFYKEEFEIGMKALDIIENKTGIKLPEDEAGFIAFHI
                     VNAQLSEGHTLASDITKLIQEVLSIVRYHFRIEFHEESVFYYRFIMHLKFFAQRLLLD
                     SAHEGETDKELLSIIKSKYNKEFECVVKIKNFIKKQYNYILTDDELIYLTIHLAKVVK
                     DSNM"
     gene            7525..9453
                     /locus_tag="ACGI5H_003179"
     CDS             7525..9453
                     /locus_tag="ACGI5H_003179"
                     /EC_number="2.7.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003440045.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_function: GO:0015573 - beta-glucoside transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA];
                     GO_process: GO:0015759 - beta-glucoside transport
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="beta-glucoside-specific PTS transporter subunit
                     IIABC"
                     /protein_id="HFG9698871.1"
                     /translation="MGKYKQLAQEIVNNVGGKENISGLVHCITRLRFTLKDESIANDN
                     VLKNMEGIVTVMKSGGQYQVVIGNHVEAVYKDVVEIIGLDDSSTSSETKKSGNILDKG
                     IDIISGIFQPVLGIMAACGMLKGFNALFVAMGLYSDVSGGYMVINAAGDALFTFLPLF
                     LGYTSAKKFGLKPMLGLALGAAVCYPAIQGSSISAGADVMYTLFKGTMFASPVYIDFF
                     GLPIVSIDYTGTVVPIIFIVYFASRCEKLFNKCVPNLVKFFFVPMLTLLITVPVALIV
                     IGPIATFGSTLISQIVISIRDFSPLLAGAIVGFTWQILVIFGMHWGFIPVYINNVMTL
                     GYDNVMMPFFACTFASSAVVLAIFFKTKDKKLKEMAIPNFISGIFGVTEPAIYGILLP
                     LKKPFIISCIASGIGGAFYGFFNLRKFITGGMGIFELPAMIEPDGGMGNLIVALSGIA
                     ISMVVAFVLTMILYKDEKVEESKKVRNKGKEEIKEVKSTKLEREIVTSPIKGEVLKLS
                     DIEDAAFASGVLGQGVAIIPSDGKVVAPVDGVVTTLFPSLHAIGILSDTGVEVLIHIG
                     LNTIQLEGRGFEACIKQGDRITKGQTILNFDVDAIKELGYSTVTPIVITNSSQFLDVV
                     ETESKNIELEDNLITVLF"
     gene            9514..10941
                     /locus_tag="ACGI5H_003180"
     CDS             9514..10941
                     /locus_tag="ACGI5H_003180"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898224.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004553 - hydrolase activity, hydrolyzing
                     O-glycosyl compounds [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="6-phospho-beta-glucosidase"
                     /protein_id="HFG9698872.1"
                     /translation="MSFKNDFLWGGATAANQCEGGYNEDERGLANVDVCPTGKDRTAV
                     ITGKLKMFDFDDEHYYPAKTGIDMYHNYKEDIKLFAEMGFKVYRMSIAWSRIFPKGDE
                     ETPNEKGLQFYENIFKECKKYKIEPLVTITHFDCPMHLVKKYGAWRNRKMIGFYEKLC
                     NVIFRRYKGLVKYWLTFNEINMILHAPFMGAGICFEEGEDVEKIKYQAAHHELVASAI
                     ATKIAHEVDSNNLIGCMFAAGSVYPYSCNPNDVWEATKLDRENYFFVDVQSKGKYPNY
                     ALKYMEQKGITPEMEPGDIELLNKYTVDFISFSYYNSRCVRTDENADDMAEGNIFTSA
                     KNPYLSYSQWGWPIDPLGLRITLNHVYDRYEKPLFVVENGLGAKDIADENGYVEDDYR
                     IDYIREHIKAMHDAVSIDGVDLLGYTTWAPIDLVSAGTGEMEKRYGFIYVDRDNSGNG
                     SLRRMKKKSFEWYKKVIASNGEDLY"
     gene            11352..12128
                     /locus_tag="ACGI5H_003181"
     CDS             11352..12128
                     /locus_tag="ACGI5H_003181"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nitroreductase family protein"
                     /protein_id="HFG9698873.1"
                     /translation="MKYQHIIEVDKELCIGCGLCKNDCPVNNIIIENKKSVIKKQDCL
                     MCGHCAAICPTKAITLTGFDEPPIELTNKPKLDSDELLMAIKSRRSIRKFKDKEVSSE
                     IIKQIIEAGRYTPSAKNSQDVSYIVLDNKKSIYENEAVKFFRKIKPIANIAIKYSKEV
                     EIDDNFFFKHAPIAIMIITKDKISGSLAASNMALMAESYGLGVLFSGYFSDVANNSPK
                     LKKLLGLKRSNHVLTTLVIGYPDVKYRRTAQKEVATVRYL"
     gene            12144..12509
                     /locus_tag="ACGI5H_003182"
     CDS             12144..12509
                     /locus_tag="ACGI5H_003182"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003440040.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="metalloregulator ArsR/SmtB family transcription
                     factor"
                     /protein_id="HFG9698874.1"
                     /translation="MEKECQQRMQEITSKFKECRKAISAMGDETRQLILIALLESDFN
                     GIRVGEITKKTHLSRPAVSHHLKILKEAEIVNLRREGTKNYYYLDSKKSQWRSLTELI
                     NLIFVGIQHISENDIRKGD"
     gene            complement(12685..13434)
                     /locus_tag="ACGI5H_003183"
     CDS             complement(12685..13434)
                     /locus_tag="ACGI5H_003183"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003440038.1"
                     /note="N-terminal region resembles flavodoxins. C-terminal
                     ferrodoxin region binds two 4Fe-4S clusters; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EFR1 family ferrodoxin"
                     /protein_id="HFG9698875.1"
                     /translation="MILYFSGTGNSRYVARKIAQELNDELISLNQLIKEEKTDELIST
                     DKPFIFVCPTYAWRLPIVVTDFIKETKFLGSNRVYFVMTCGGDTAKSINYIQKLCKYK
                     EWQLKGMAEIKMPENYIALFSTTDKETSKQMIKEADKQIYRIISDIRNENEFEIITPS
                     GLGGTIKSGIINTVFYKTIISAKGFHYTDKCIGCGKCVELCPLNNINLKNKKPVWKNN
                     CTHCMACICGCPTEAIEYKNKTQNRERYYLE"
     gene            13656..13784
                     /locus_tag="ACGI5H_003184"
     CDS             13656..13784
                     /locus_tag="ACGI5H_003184"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728830.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9698876.1"
                     /translation="MKDYKYKGYFEGVEIFDNVNDLNLNTLTTVSRFVFVFLFTIT"
     gene            13912..14094
                     /locus_tag="ACGI5H_003185"
                     /pseudo
     CDS             13912..14094
                     /locus_tag="ACGI5H_003185"
                     /inference="COORDINATES: protein motif:HMM:NF024835.4"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
     gene            14122..14337
                     /locus_tag="ACGI5H_003186"
     CDS             14122..14337
                     /locus_tag="ACGI5H_003186"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006774905.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AbrB/MazE/SpoVT family DNA-binding
                     domain-containing protein"
                     /protein_id="HFG9698877.1"
                     /translation="MVPPKGKFFFGAVVVGERGQIVIPKEAREVFNINAGDKLLVLGD
                     EERGLGIVHQRDLINFIGHVGVVHKEE"
     gene            14369..15556
                     /locus_tag="ACGI5H_003187"
     CDS             14369..15556
                     /locus_tag="ACGI5H_003187"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003440033.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016758 - hexosyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="macrolide family glycosyltransferase"
                     /protein_id="HFG9698878.1"
                     /translation="MSKIVFFSIPAYGHTNPTIEVVRELVDRGNEVLYYSFNEFKDKI
                     EGAGAKFICCDKYLPELLPGDEKKIGKDFPGLIEMIVDTTISLDEKVCRELKDFNPDC
                     IVSDSLSFWGKLFAQKLNIPYVCSTTTFAFNKHTAKLMKQNFIEIIRMIFGVRRINKK
                     IKLLQRKGYEVKNFISIVSNDNDTDTIVYTSKEFQPMVETFSSKYSFVGPSVSKLIIE
                     PKERKRKLIYISLGTINNKNVSFYKNCINAFKDSDVDVIMSVGRSTDIKSLGNIPNNF
                     EVKNSVEQIAILQKTDVFVTHSGMNSVNESLYYGVPMVLFPQHSEQRMVAKRVVHLGA
                     GIMLKEDKSESIKKAVFQVINDNEYKENATKLSKSFYNAGGSKKAADVILQIICNSRQ
                     VDI"
     gene            15748..16152
                     /locus_tag="ACGI5H_003188"
     CDS             15748..16152
                     /locus_tag="ACGI5H_003188"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427327.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3139 domain-containing protein"
                     /protein_id="HFG9698879.1"
                     /translation="MKKYKVIFIVLIIGIISVTGFVVYKNCIKPWKDAETYIDKYMVK
                     QDISKDNIKSITKEKAKKASYEGILYKVYYKDDPRYEYQYFYSDNYYALYVNKVMLQI
                     YDMENNNKLLRSNEELKSVKYPPIYLKYKPDK"
BASE COUNT         6385 a         1699 c         2866 g         5266 t
ORIGIN      
        1 gagaataaga taacaataat gaggatataa aaatgtattt gctatatata taattatata
       61 catagatatc taatattgat atttaatatg aaagtattga aaatagacaa tattaattat
      121 agtgagtaaa aaatataatt ggatttttaa attgaattat ttaaaaggta tagtatgaaa
      181 aaaatcttat aactaaatat gagatagaaa ttataaaatt ttatactgtg aaagaggtag
      241 atgcatgaaa ttagggaaag attttttatg gggaggggca atttcagcca atcaaagtga
      301 aggattttat ttagatggag gaaaaggttt atctcagttt gataaactcc cattaaatga
      361 taagagatta aaaaatgtat gtttagatga ggataatatt ttaaatgaaa ataatcaata
      421 ctatccaagt catataggga ttaaattttg tgaaaattac aaagaagata tagcaatgtt
      481 agcagaaata ggttttaaat gttttagatt ttctatatct tggtcaagaa tattcccaac
      541 aggagaagaa agtgaaccaa atgaaaaggg attacaactt tatgataata taataaaaga
      601 attaaaaaaa tataatatag agccattaat aacgataagc cactttgata taccttattc
      661 tctagttgaa aaatattctg ggtgggctga tagaagagtg gttaatttat atgtaaaata
      721 tgctgaaatt ttgatgaaaa gatataaaga tgatgtcaaa tactggattc cttttaacga
      781 aatgaatatg ataatgcata ttccatatat aggtgctggg ttaactttta tagctgatga
      841 aaatcaactt cagaaaaaat atcaagcagc acaccatcaa ttattagcta atgcaaaaac
      901 tatagaaata ggaaggtata taaataaaga atttaagttt gggtgtatgt tagctgctgg
      961 aaaaacatat ccatacacat gtaaaccaga agatgtattt gcaactttag agcatgagag
     1021 gcataatttg tttttttctg atgttcaagt taggggtgtg tatccaagct ttatgagtta
     1081 ttatttaaaa tcaaatcaaa taaaattaat aataaaagag gaagatttat caacacttaa
     1141 ggataatact gtagattttg tatcttttag ctattattct agtgcttgta gttcagctag
     1201 agctgaaggt ttagaaaaat caaaggcaaa cggaccagaa accataaaaa atccatatct
     1261 tccaaaatca aatagtgtat ggcaaaacga ccctgtaggg ttaagaataa ctatgaatca
     1321 gttatatgaa aggtatcagt tacctttatt tatagtagaa aatggactgg gtactcaaga
     1381 tattgtaaat gaagatggaa aaataattga tgattatcgt atagattaca tgaaagaaca
     1441 tattaaaaat atgattcttg gagtaaatga agatggaata gagcttatag gatatcttat
     1501 gtggggatgt atagatgtaa ccagtgtaag tgaaggaaag atgacaaaac gatatggcat
     1561 aattcatgtt gattctgatg actatggaag aggctcattt aaaagaacta aaaaacaaag
     1621 tgctttttgg tataaaaaag taatagaaac agatggagaa attttattta atgatatgga
     1681 aactcatgca taattcattt taagaaagga gtgttattat gagtttaata tttactacta
     1741 aggaccaact tgtagagcta gggtttagta aggatacaat aaaatccaat gaaacgttgt
     1801 ttacactagc taatggacat ttaggagtta gagggaatat tgaagagtct gattttaata
     1861 atgagtatgt agataatatg ggtacatatg taaatggatt ttatgaagaa tctccaatta
     1921 catatggaga aagcgcttat ggctatgcaa aacaaaatca gactatctgt aagttaccta
     1981 atgctcatat agtaaatttc tctattgaag gagattgctt tgatttatca aaaggtatta
     2041 caagtgaaca tactaggata ctagatttaa atgaagggat tcttaaacgt tcatttatat
     2101 gggaaaactc tcgtggtaga aaagttaaag tatctataga aagattagta tcacaagata
     2161 tagaagaatt aatgatgatt tcatatacaa taacaccatt gaattttaat ggaaaaataa
     2221 aatttaaaaa taaaatggaa aatagtatgg agaagtttaa ttgtgaaaaa gtagatgacc
     2281 caagagtggc atctataaat aagaagcaat ttaaaattaa tgtaaaaaaa tataacaata
     2341 agtattttat gaatttagtt acagaaagaa gtagattagg gttatggtgt gggtttgatt
     2401 catatattac ttgtggaaat attacaaatg agacctataa tgtttcagat gaatgtattg
     2461 agcgagaaat agaagtctat gccaaaaaag atgaaaggtt aaatttagaa attgttgtag
     2521 gctatagtag agtatattct gatttaaatc taaatgaaga acgtttaaaa tcattagaat
     2581 gtctggagtc gttaaaatgt ttagaatcag aagcacattt aaaatcatta gaattggttt
     2641 taagagaagc atgtaatatt ggatttgata aagtcaaaaa tattcagaga aagaaaatga
     2701 atgagttttg gacaacctct gatgtagaga ttgaaggcga taaaactctt caactgggga
     2761 taaaaaccaa tttatttcat atttatcaat cagcaggaag agatggaaag actaatatat
     2821 cagcaaaagg tcttacaggt gatggctatg aggggcatta tttctgggat acagaaatgt
     2881 atatattacc attttttata tatactcaac catccattgc tagagcttta ttagattata
     2941 gatactcaat cttagatgca tcaagagaaa gagctagaga acttggaata aataaaggtt
     3001 gcttatattc atggagaact ataaatggta atgaatgcag tgcatattat ccagcaggaa
     3061 cagcacagtt tcatataaat gcagatatag cttatggtgt tagaacgtat tttgaagcaa
     3121 ctaatgatga agaatttatg atgcaaaatg gcttagaaat tcttatagaa acatcaagat
     3181 tttgggttga atttggagat tatatagaat caaaaaataa taaattctgt ataaatggag
     3241 taacaggacc agatgaatat acagcaatag taaacaataa ttactacact aatttaatgg
     3301 ctaagtataa tttaatatat gcagtacaga tggtagataa atttaagcat aatttatttt
     3361 caaatgaagt atttagaaaa gttaaattac aagaatatga agtgaaaaac tggataaatg
     3421 ccgctcaaaa tatgtattta ccatatgatg aagagaagaa aataagcaaa caagacgatt
     3481 catttttaga aaaatcagta tgggatttta aaaatacacc aaaagaaaaa tatccattac
     3541 ttctccatta tcatccatta acaatatata gatatcaagt aaataaacaa gcagatactg
     3601 tactttcagc gttgcttttc cctgatgagt ttagcttaga acaaaagaag agagattttg
     3661 aatactatga aaaaataact actcatgatt catctttgtc aaggtcaata tttggaatga
     3721 tggcaagtga aattggaaat catgaaaaag cttataacta ttttatggac acagcattaa
     3781 tggatattaa taacctacaa aaaaatacaa gtgatggaat acatgctgct aatatgggtg
     3841 gaacatggat gagtttagta tatggatttg caggaatgaa aataaaaaat gataaattaa
     3901 gttttgaacc aaggatacct aaacactgga aaaatattaa atttaatata ttatttagag
     3961 ataatttagt ttttgtaaat atagaagaat ataaatctta ttataagtta atcaaaggta
     4021 gaaatataac catattacat gataataaag aaataaaatt atcaaagaac ataatagaag
     4081 ttaataattg ttttaaaggg agtaattaat atgaaagcag tcttatttga tcttgatgga
     4141 gttataacag atactgctaa gtatcatttt gaagcttggc atgagatagc aaaatcgcta
     4201 gatatagaaa tagatgaaac ttttaatgaa aaattaaaag gcataaacag ggaagaatca
     4261 ttagataaaa tattgttatc tgctaataaa gtagatagtt atactaaaga ggaaaagtta
     4321 aaggtgtgtg aagaaaaaaa taacatttat ataaagttaa taaactcatt aacatataaa
     4381 gatatattac cagggataaa tgagcttata aaagaactta aaaaaaataa tgtgaaattg
     4441 ggaatagcat ctgctagtaa gaatgcacct aggatattag aatctttggg agtaaaagat
     4501 gaatttgatt gtatagtaaa tccatcttta ttaaaaaggg gaaaaccata tcctgatatt
     4561 tttattgaag ggagcaagat gctaaattta aaacaatatg attgtgtagg aatagaagat
     4621 tcttattcgg gtattaaagc tataaatgct gccaatatga catcaattgg tgtggggaaa
     4681 aaagaagtac taggaaaatg tgaccatatt gtagaagata ctagcttatt aaattacaat
     4741 acactattac aagcttggag taaaaagatt aatttggatt aaaattatat taaaaattat
     4801 tttaaaagag aggataaggt atgaagaata aatatgaaga tgtagctcaa ttgataattg
     4861 atggacttgg aggaaaagat aatataattg acttaactca ttgtatgaca cgattaaggt
     4921 tcatcttaaa agatgaaaag aaagtcaatg cagataaatt aaaatctata gataaggtag
     4981 ttggagtaaa ctcaacttca actcaatatc aggtcataat aggtaatgag gtaggtgttg
     5041 tatttaatgc aataataaat aaggggataa ataccacagg agatattaaa agcgatataa
     5101 aaaataaaaa taaaaaaaat agtattttaa ataatataat agatacaata actggttgta
     5161 tgacacctat gataccagcc cttacagcat ctgggatgat aaaagttata ttatctcttt
     5221 gcaccacttt taattggcta tcatcaaatt caagtacata tagagtatta gatataatag
     5281 gagatgtagc attttacttt atgcctataa tacttgcaat aaatgcagct aaaaaattta
     5341 atgttaatac atcaatagca gttatagtag taggtgtgtt tttacatcca aatttctctg
     5401 catgggtatc aagtggggac cctatatcat ttataggagt accaattcaa ggtgttatat
     5461 atgcagcatc tgttatccct gcacttttaa cagtatggat gatgtcatat atagaaaatt
     5521 tcattgataa attaacacct agcatgttaa aaacaatttt aaatccaact ttagtattat
     5581 taataagtgc gccaatagca ttaatagtaa ttggaccaat aggaaatttc ttaggagagg
     5641 gattagctag tataataaat ttactacaag gaaggttagg atttataatg gtttgtttat
     5701 tagcagctgc aatgccattt atcgttatga cagggatgca tcatgcattg actcctatat
     5761 tcatatcagc atttgcaact acaggacaag aatcgctaat attaatatct caagtttgtg
     5821 ctaatttagc gcaaggtggc gcaacattag ctgtagcatt aagaagcaaa gatagtaaga
     5881 tgaaacagtt agcatcagct gcatggatat cagctattat gggtataact gaaccagctc
     5941 tttatggagt tacattgaaa cttaaaaaac ctgctatgtt agcatctata ggagcaggaa
     6001 tcgcagggtt atttgcagga attactcatg tgactttata tgttccacaa aatagtataa
     6061 tggcagtact tggattatca ggggaaaagg ggatttcaaa tatagtaaat ggacttatag
     6121 ttatatttat agcattggtt gctccattta ttatgacata tgtttttgga gttgaaaaaa
     6181 atgttaaata aagtacagat aatgtagtag aggaagtata atattaacta tttacattaa
     6241 tagaattttt attattattg actataactt gttttgtatt tatattgatg caaagaaata
     6301 agttaatatt aataagaata attattataa ctgacaaaaa gcaacataaa agattgatga
     6361 agtatatgga aataaaaagt tgacaaaata tgtctgatgt tttatcatat taattggaat
     6421 taggtagtaa ttgtttaagt acaagctaag cttattcatt aataatagca gtatcctagg
     6481 aaggagtatg cccattatta tggataagct ttttttatgc ttaaaaggag gataatcatg
     6541 ataattaata agatattaaa caataatgtt gtaatcacat tagatgataa tgatgaagaa
     6601 gttatcgtta tgggtaaagg aattggttat caaaaatcaa aaggcaatct aatagataaa
     6661 actaaagtaa ataaagtatt tagaatatca aataaagaaa tatcaaacaa actacaagaa
     6721 ttactcaata atattcctat agaacacatg aaattatcaa gtgaaattat agaatacgca
     6781 caaataaagt taaacaagaa gctaaatgaa agtatttaca tatccttaag tgaccataca
     6841 tattctgcaa ttcaaagaat gaaagaagga ataaatgtaa aaaatgcaat cctttgggaa
     6901 attaaaagat tttataaaga agagtttgaa attggaatga aagcactaga tattattgaa
     6961 aacaaaacag gtataaaatt accagaagat gaggctggat ttatagcctt tcatatagtg
     7021 aatgctcagt taagtgaagg tcatactttg gcatctgata ttacgaagtt aatacaagaa
     7081 gtacttagca tagttaggta tcattttagg atagaatttc atgaagaatc agtgttttat
     7141 tatagattta taatgcattt aaagtttttt gcgcaaagat tgcttttaga tagtgcacat
     7201 gaaggtgaga cagacaaaga attactaagc attattaaat ctaaatataa taaagagttt
     7261 gaatgtgtag ttaaaattaa aaatttcatt aaaaaacaat ataactacat attaacagat
     7321 gatgagctta tatatttaac aatacattta gctaaagtag ttaaagactc aaatatgtaa
     7381 gtgaaataat ttttcagcag tatattaaga atgattgaaa ggagtgatac taacaaaatt
     7441 atacttatgg ttggatggta acattgagtt ggccaaacct tcaaatttca aaaaattaat
     7501 ttaaacgaaa tatggaggag aaaaatggga aaatacaaac aattagcaca agagatagta
     7561 aacaatgttg gtggaaaaga aaatattagt ggattagtac actgtattac aagattacgt
     7621 tttactttaa aagatgaaag tatagcaaat gacaatgtat taaaaaacat ggaaggtatt
     7681 gttactgtaa tgaaaagtgg aggacaatat caagtagtta taggaaatca tgttgaagct
     7741 gtctataaag atgtagttga aataattggt ttagatgatt caagtacaag ttcagaaact
     7801 aaaaaatcag gtaatatact agataaaggt atagatataa tatcaggaat ttttcagcca
     7861 gtgttaggaa taatggcagc ttgtggtatg ttgaaaggat ttaatgcatt atttgtagca
     7921 atgggattat atagtgatgt atctggtggt tatatggtaa taaatgcagc gggagatgca
     7981 ttatttacat tccttccttt gttcttagga tatacttcag ctaagaagtt tggattaaaa
     8041 ccaatgttgg gattagcact aggagctgca gtatgttatc ctgctataca aggtagcagt
     8101 atatcagcag gagcagatgt gatgtacact ttatttaaag gaacaatgtt tgcatcacca
     8161 gtatatattg atttctttgg actaccaatt gtatcaattg attatactgg aacagtcgta
     8221 ccaattatat ttatagtgta ttttgcttct aggtgtgaaa aattatttaa taagtgtgtt
     8281 ccaaatttag ttaagttttt ctttgtgcca atgcttacat tattaataac agtgcctgtt
     8341 gcacttatag ttataggccc tatagcaaca tttggttcta cacttatttc acaaattgta
     8401 atttcaataa gagattttag tccactattg gcaggtgcta tagtaggatt tacttggcaa
     8461 attcttgtta tttttggtat gcactgggga tttattcctg tatatataaa caatgttatg
     8521 actttaggat atgataatgt tatgatgcca ttctttgcct gtacatttgc aagttcggca
     8581 gttgtgttgg caatattttt caagactaaa gataaaaaac taaaagagat ggcaatacca
     8641 aactttatat ctggtatatt tggagttaca gagccagcaa tttatggaat attattgcct
     8701 ttaaagaaac catttataat aagttgtatt gctagtggta ttggaggcgc tttctatgga
     8761 ttctttaatc ttagaaaatt tataactgga ggaatgggaa tatttgaact tccagcaatg
     8821 attgaaccag atgggggaat gggtaactta atagtagctc tttctggtat agctatatca
     8881 atggtcgtag cttttgtatt aactatgatt ttatataaag atgagaaagt agaagagtct
     8941 aaaaaagtaa gaaataaggg taaagaagaa ataaaagaag tcaagtctac taaattagaa
     9001 agagaaatag taacaagtcc tataaaaggt gaagtattaa aattaagtga tatagaggat
     9061 gcagcatttg catctggtgt actaggtcaa ggggtggcaa taatacctag tgatggaaaa
     9121 gtagttgctc cagtagatgg ggtagttaca accttatttc ctagtctaca tgctataggg
     9181 attctttctg atacaggtgt tgaagtgctt attcatattg gattaaatac tattcaatta
     9241 gagggaagag gttttgaggc atgtataaaa caaggtgata gaattacaaa aggtcaaact
     9301 atattaaact ttgatgttga tgcaataaaa gagttggggt atagtactgt aactccaatt
     9361 gttattacaa attcatcaca atttttagat gtagtagaaa cagaaagtaa aaatattgaa
     9421 ttagaagaca atctaattac agtcttattt tagtaaagat tgaggtatta gcataatcta
     9481 gtgctttggt tataatttta ggaggctttg actatgagtt ttaagaatga ttttttatgg
     9541 ggaggagcta ctgcggccaa tcaatgtgaa ggtggataca atgaagacga aagaggattg
     9601 gcaaatgtag atgtatgtcc aacaggaaaa gatagaacag cagttattac agggaaacta
     9661 aaaatgtttg attttgatga tgagcattat tatccagcta aaactggtat tgatatgtat
     9721 cataattata aagaagatat aaagttattt gctgaaatgg gatttaaagt atatagaatg
     9781 agcattgcat ggagtcgaat atttccaaaa ggtgatgaag aaacaccaaa tgaaaaggga
     9841 cttcaatttt atgaaaatat atttaaggag tgtaaaaaat ataaaataga gcctttagtc
     9901 actattacac actttgattg tccaatgcat ttagttaaaa agtatggtgc atggcgtaat
     9961 cgaaaaatga taggtttcta tgagaaatta tgcaatgtta tctttagaag atataaagga
    10021 ttagtgaagt actggctaac tttcaatgaa ataaatatga ttttacatgc tccatttatg
    10081 ggtgctggta tttgctttga agaaggtgaa gatgttgaaa agataaaata tcaagctgcc
    10141 catcatgagc ttgtagctag tgcaattgca actaaaatag cacatgaagt tgattcaaat
    10201 aacttaattg gatgtatgtt tgcagctgga agtgtatatc cttatagttg taatcctaat
    10261 gatgtatggg aagctacaaa gttagataga gaaaattact tctttgtgga tgtacaatct
    10321 aaaggtaaat atcctaacta tgcgttaaag tatatggagc aaaaaggtat tacaccagaa
    10381 atggaacctg gtgatattga attattgaat aaatatacag tagattttat ttcattttca
    10441 tattacaata gccgttgtgt tagaaccgat gaaaatgcag atgatatggc tgaaggaaac
    10501 atatttacat ctgctaaaaa tccatatctt tcatacagtc aatggggatg gccaattgac
    10561 ccattaggtt tgagaattac actaaatcat gtatatgata gatatgaaaa gccactattt
    10621 gttgtagaaa atggattagg tgctaaagat atagctgatg aaaatggtta tgtagaagat
    10681 gattacagaa ttgattatat aagagaacat ataaaagcta tgcatgatgc agtttctata
    10741 gatggggtcg atttattagg ttatactaca tgggcaccta ttgatttagt aagtgctggt
    10801 acaggtgaaa tggaaaagcg ttatggattt atatatgtag atagagacaa tagtggtaat
    10861 ggaagtctaa gaagaatgaa aaagaaaagt tttgaatggt ataagaaagt aattgcttca
    10921 aatggtgaag atttatatta gacaagaaat ctatgttaaa taagaaattt gtattaaata
    10981 agaagagtat aaaaattaat aataagtata atttttaact tttttaacta tagaaaatca
    11041 atacagaatt attttacatt gtatttatgc aatagtatga ttcacaaata aaattttaga
    11101 aaataaaatt gttaagaagt atgggaagta agtgcaattt actttgtaat aaaagatgaa
    11161 aaaggcaagc ttaggtttta agcttgtctt ttttattatg tataaactat gatactttaa
    11221 aattctatga aaaatttatt taatagagaa attaaaaatt taatggtaat caaattcttt
    11281 accaatgaat ataaaaaatg tctacgtgtt ataatagttt aaactaataa acgaaaggta
    11341 gatgaatgaa tatgaaatac caacatataa tagaagttga caaagaactt tgcattggat
    11401 gtgggctttg taaaaatgat tgtccagtaa acaatataat tatagaaaat aaaaagtcag
    11461 taattaaaaa acaagattgt ctaatgtgtg gacattgtgc agcaatatgt cccacaaaag
    11521 ctattacctt gacaggattt gatgaacctc ctatagaact tacaaataag ccaaagctag
    11581 attcagatga attactaatg gcaattaaat ctagaagaag tatacgtaaa tttaaagaca
    11641 aagaagtttc ttcagaaatt ataaagcaaa ttattgaggc aggtaggtat acccctagtg
    11701 ctaaaaattc acaagatgta tcatatattg ttttagacaa taaaaagtca atttatgaaa
    11761 acgaagcagt gaaatttttt agaaaaataa aacctattgc aaatatagct attaaatatt
    11821 caaaagaagt tgagattgac gataactttt tctttaagca tgctcctatt gcaataatga
    11881 taattacaaa agataagatt agtggttcac ttgcagcatc aaatatggca ttaatggcag
    11941 agtcttatgg cctaggtgtt ttatttagtg gatatttttc agatgtagca aataattcgc
    12001 caaaattaaa aaagctttta ggtctaaaac gcagtaatca tgttcttaca acattagtaa
    12061 ttggataccc agatgttaaa tatagacgta ctgcacagaa agaagtagca actgttagat
    12121 acttataaga gagggtggat tttatggaaa aagaatgtca acaaagaatg caagaaataa
    12181 cgtctaaatt taaagaatgt cgcaaagcta tctctgctat gggtgatgag actagacaat
    12241 tgattttaat tgctctctta gagagtgatt ttaatggtat acgagtggga gaaatcacaa
    12301 aaaaaacaca tctttctcgt cctgctgtat ctcatcatct taagatatta aaagaagcag
    12361 agattgttaa tttgcgtaga gaaggaacaa aaaattatta ttatcttgat tcaaaaaaat
    12421 cacaatggag gtcactaaca gagctaataa atcttatatt tgttggaata caacatatta
    12481 gtgaaaatga tataagaaaa ggtgattaaa ttatacttga tttaatacaa aaagattgat
    12541 ttaggaacta aaaagaacta aaaagttcac tttgagacac tatcttttga actataccca
    12601 tcttaggaga cagttaaaat atgtaaaact gtataaaaca atgggtatag ttcattttat
    12661 aatggtttaa atattaagaa tatattattc taaatagtat ctttctctgt tttgagtttt
    12721 atttttatac tcaatagctt cagtggggca accacaaata catgccatac aatgagtaca
    12781 gttatttttc caaactggtt ttttgttttt taaattaata ttatttaaag gacatagctc
    12841 tacacatttt ccacagccaa tgcatttatc agtataatga aatcctttgg cactaataat
    12901 tgtcttataa aaaactgtat ttattatacc acttttaatt gtacctccta agccactagg
    12961 agtaataatt tcaaattcat tttcatttcg tatatcagaa ataatcctat atatttgttt
    13021 atctgcttct ttaatcattt gttttgatgt ttctttgtct gttgtagaaa ataaagctat
    13081 ataattctct ggcattttaa tttctgccat accttttaat tgccattcct tgtatttaca
    13141 tagtttttga atatagttta tggattttgc tgtatctcca ccacaagtca ttacaaagta
    13201 aactctgttg cttcctagaa attttgtttc ttttataaaa tccgtaacca ctattggcaa
    13261 tctccatgca taagtaggac atacaaatat gaatggttta tctgttgata ttaattcatc
    13321 tgttttttcc tcttttataa gttgatttag tgatatcagt tcatcattta attcttgtgc
    13381 aattttacga gccacatatc ggctattacc agttccgcta aaatataaaa tcataataat
    13441 atctccctaa ctatttttta ttttaactct taatttttta tttattatag taatttattg
    13501 atatattcta ttcaaatgta tgtaaaattt agtagttaag aaaattataa cacattagta
    13561 atttttatac ttattggtaa agaatttgat taccattaaa tttagcaaca agacatcaac
    13621 tggacttgta tatgagaagg gataataatt tgcttatgaa agattataaa tataaaggtt
    13681 attttgaagg tgtagaaata tttgataatg taaatgacct taacttaaat actttaacaa
    13741 cagttagtag atttgtgttt gtttttttgt ttacgataac ttaaggaaat atgttacctg
    13801 aacaataaat ttatataata aaagtatata aatatatata tgaatgttaa gattagttga
    13861 tagaatttaa ataataaatc caatattata aacataggag gtatgaaaaa tatgattaat
    13921 gagaatttaa aaagtctaag aaaaatcaat cagtatacac aagaagaatt agctgaaaaa
    13981 cttaatgttt ctagacaatc aatagcaaaa tgggaaagtg gagaatctat tcctgatata
    14041 ggtagttgca ttaaacttgc aaaattgtac aatgttaaac tagatgactt agttaatcat
    14101 tcggaagaaa aaacaggtat tatagtacct cctaaaggaa agtttttctt tggagcagtt
    14161 gtagttggtg aacgtggtca gattgtcatt ccaaaagaag caagagaagt atttaatata
    14221 aatgcaggag ataaattatt ggtacttgga gatgaggaaa gaggattagg aattgttcat
    14281 caacgtgatt tgataaattt tataggtcat gtgggagtag tacataaaga agaatgattt
    14341 aaaaaaatta taaaaggagg tatgaaatat gagtaaaata gtatttttta gcattcctgc
    14401 atatggtcat actaatccta ctattgaagt agttcgtgaa ttagtggata gaggaaatga
    14461 ggtattgtat tattctttta atgaatttaa agataaaatt gaaggtgctg gagcaaaatt
    14521 tatttgttgt gataaatacc ttccagaatt actccctgga gatgagaaaa aaattggtaa
    14581 ggattttcct ggattaattg agatgatagt agatactact atttctttag atgaaaaagt
    14641 ttgtagagaa cttaaagatt ttaatccaga ttgcattgta tcagattcat taagtttttg
    14701 gggaaagtta tttgcacaaa aacttaatat tccatatgta tgctctacaa caacttttgc
    14761 atttaataaa catacagcaa agttgatgaa acaaaacttt atagaaatta tacgtatgat
    14821 ttttggtgta agacgcatta ataaaaaaat aaagctttta caaagaaaag ggtatgaagt
    14881 aaaaaatttt atttctatag tttctaatga taatgatacg gataccattg tatatacatc
    14941 aaaagaattt caaccaatgg tagaaacctt ctctagtaag tattcatttg taggtccatc
    15001 agtatcaaag ttgattattg aacctaaaga gagaaaaaga aagctaatat atatttcgct
    15061 tggtacaatt aataataaaa atgttagctt ttataaaaac tgtataaatg catttaaaga
    15121 ttctgatgtt gatgtgatta tgtctgttgg tagaagtact gatattaaaa gtttaggaaa
    15181 tataccaaat aattttgagg ttaaaaatag tgttgaacag attgctatac ttcaaaaaac
    15241 tgatgtgttt gttactcatt ctgggatgaa tagtgttaat gaaagtttat attatggagt
    15301 acctatggta ttatttcctc aacattcgga gcagagaatg gtagctaaga gagttgttca
    15361 tttgggagca ggaattatgt taaaagagga taaatcagaa agtattaaaa aagcagtatt
    15421 tcaagttata aatgacaatg aatataaaga aaatgcaact aaactatcaa aaagctttta
    15481 taatgcagga ggctcaaaaa aagcagcaga tgtaatatta cagattatat gtaatagtag
    15541 acaagttgac atataataga tttgttaaaa atatatatac atacatgtaa tttaatcaaa
    15601 gtactgacag tggggtcttt taacctacca gttggggcat atatattgat gctaaatatg
    15661 agggatgtta tattttaata aaaaagataa catccttttt ttagtgcatt atatcgagtt
    15721 ttaaataata aatgaaggag gattaatatg aaaaaatata aagttatttt tatagtatta
    15781 attataggta ttataagtgt aacagggttt gttgtatata aaaactgcat taaaccatgg
    15841 aaagatgctg aaacatatat tgataagtat atggtaaaac aagatatttc aaaagataat
    15901 ataaaaagta ttacaaaaga aaaagccaag aaggcaagtt acgaaggaat actatacaaa
    15961 gtgtattaca aagatgaccc tcgatatgag tatcaatatt tttatagtga taattattat
    16021 gctctatatg taaataaagt aatgttacaa atttatgata tggaaaataa taataaactt
    16081 ttaagaagta atgaggaatt aaaaagtgta aagtatccac caatatatct taaatataag
    16141 ccagataaat gatttatgac aaaatagaat aatttttatt aaaatttatt taaaaatatc
    16201 actagagcgt ttaaat
//
LOCUS       DAYAOO010000092        16113 bp    DNA     linear   BCT 12-OCT-2024
DEFINITION  TPA_asm: Clostridioides difficile isolate ST8-SSI-h139-18
            SAMN40601845-rid21577343.denovo.093, whole genome shotgun sequence.
ACCESSION   DAYAOO010000092 DAYAOO010000000
VERSION     DAYAOO010000092.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN40601845
            Sequence Read Archive: SRR28438827
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 16113)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 16113)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-MAY-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-MAY-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002157583.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002157583.1
            Genome Coverage       :: 163x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/11/2024 16:19:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 4,038
            CDSs (total)                      :: 3,963
            Genes (coding)                    :: 3,930
            CDSs (with protein)               :: 3,930
            Genes (RNA)                       :: 75
            rRNAs                             :: 6, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 60
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 33
            CDSs (without protein)            :: 33
            Pseudo Genes (ambiguous residues) :: 0 of 33
            Pseudo Genes (frameshifted)       :: 7 of 33
            Pseudo Genes (incomplete)         :: 25 of 33
            Pseudo Genes (internal stop)      :: 11 of 33
            Pseudo Genes (multiple problems)  :: 8 of 33
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..16113
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN40601845-rid21577343.denovo.093"
                     /isolate="ST8-SSI-h139-18"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Denmark"
                     /collection_date="2018"
                     /collected_by="Statens Serum Institute"
     gene            complement(107..745)
                     /locus_tag="ACGI5H_003189"
     CDS             complement(107..745)
                     /locus_tag="ACGI5H_003189"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-2 transporter permease"
                     /protein_id="HFG9698880.1"
                     /translation="MKGLILKDLLNLKGNIKFILLFIIMFGFMSSLGDGNVNNFIGVI
                     IVLCTTMIVSTFSYDDLNKWDSYVLTMPINRNDIVLSKYLTMLIFSFIGVLVSLIVSV
                     TIGYFKNTLILNETLLINALILSISVCFGSLILPLIYKFGTERARLLMILCFLVPTLA
                     LLVFKSILENISSPISIEIILNTLVYSLPFVAILLFVISYFISSKIYSKKEV"
     gene            complement(745..1608)
                     /locus_tag="ACGI5H_003190"
     CDS             complement(745..1608)
                     /locus_tag="ACGI5H_003190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435188.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HFG9698881.1"
                     /translation="MISMDAITIKNLNKTYKDFSLQDISFSVPKGSVMGFVGENGAGK
                     TTTLKAILNLISYDSGNIEIFGLDSKKNEKEIKEQIGVVFEGSNFHENLNTDHVSKIM
                     SKIYKNWNDTLFKDYLKKLRVPDNKLIKEFSKGNKMKLSIAVALSHKPKLLILDEATS
                     SLDPIVREEILDIFLDFIQDEEHSIILSSHITSDLDKIADYITFIHKGKIVFSENKDE
                     LIDTMGVLKCKPSDFDNLSREDYSYYRKSQFGYEVLLKDKHRFISRHPNCIVDNTSIE
                     EIMLFYVRGDK"
     gene            complement(1605..1979)
                     /locus_tag="ACGI5H_003191"
     CDS             complement(1605..1979)
                     /locus_tag="ACGI5H_003191"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424232.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HFG9698882.1"
                     /translation="MNIVISNSSGKPIYEQITTQIKSMIISGELPEGSALPSMRLLAK
                     ELRISVITTKRAYSDLERDGFIETVTGKGSFVSSKNMDFVKEEQFRLIEEYLQKAVDT
                     AKSSDITYDELKDILFLLYKGE"
     gene            2346..2750
                     /locus_tag="ACGI5H_003192"
     CDS             2346..2750
                     /locus_tag="ACGI5H_003192"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861430.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0006260 - DNA replication [Evidence IEA];
                     GO_process: GO:0006276 - plasmid maintenance [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="replication/maintenance protein RepL"
                     /protein_id="HFG9698883.1"
                     /translation="MDKTLKKDLNQEYTESKSLIMNKSKYMNVCFKNYIKVVEGMYTK
                     RDLIPLKLINSMDKNNKIRKTLYELSCEFEYPKTSLSSLFTELKKMDFLQRVKNGEYM
                     INPHIAYKGSRADKESLLAEYNQIKRPNKVSK"
     gene            2767..3363
                     /locus_tag="ACGI5H_003193"
     CDS             2767..3363
                     /locus_tag="ACGI5H_003193"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435191.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9698884.1"
                     /translation="MSLKLDRNVLQWFDYVFENEKTSLRHYNFNCTLKEISSTSLNKV
                     AFILEKNNSKYWKLYFEIPAEVTLKLKQNIHPLFREYIYEQISLYNNNQIYNFVNSNI
                     LKVFNNIAIYQYNILENLYTIDFKKSFIDKCQYLLIGEKRLIDEDLYLIAKSKEVFDF
                     FNLDGTFNLTLSFDIQKNENLLDSLLELRKSIIINERI"
     gene            3400..5994
                     /gene="clpB"
                     /locus_tag="ACGI5H_003194"
     CDS             3400..5994
                     /gene="clpB"
                     /locus_tag="ACGI5H_003194"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424228.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_process: GO:0009408 - response to heat [Evidence IEA];
                     GO_process: GO:0042026 - protein refolding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent chaperone ClpB"
                     /protein_id="HFG9698885.1"
                     /translation="MDVEKMTLRVQKSLNEAYNEAVKNHNQQVDVIHLFSALINQEDG
                     LIPNIIEKMNISIDSLRNTVNFEIDKLPKVYGEGADSQGVSATRKINEVLIKAESISK
                     EFKDSYISVEHVMLAMMETESKSAVGKILKQYNINKNNFLNILSQVRGSQRVETQDPE
                     GTYDALARYGTNLVDLAKKNKLDPVIGRDEEIRRIIRILSRRTKNNPVLIGEPGVGKT
                     AIVEGLAERIVRGDVPEGLKDKIVFSLDMGALIAGAKYRGEFEERLKAVLKEVQSSDG
                     KIILFIDEIHTIVGAGKTEGSMDAGNLIKPMLARGELNCIGATTFDEYRKYIEKDKAL
                     ERRFQPVIAEEPTVEDTISILRGLKERFEIHHGVRIHDNAIVAAAKLSHRYIQDRFLP
                     DKAIDLIDEAGAMIRSEIDSLPTELDVVRRKLFTLETEREALLKENDDKSKSRLDDIQ
                     KEIAELKSKNDEMTAKYEKEKSQILDIKNLKAQLDEAKGKAEKYEREYDFNKAAEVKY
                     GEIPKLEEQIKQYEENMNDGSENSLLKEEVTEEEISSIVSKWTGIPVTKLVEGEREKL
                     LKLEDELHKRVIGQDEAVTAVSNAVIRARAGLKDERKPIGSFIFLGPTGVGKTELAKT
                     LARNLFDSEDNIIRIDMSEYMEKHAVSRLVGPPPGYVGYEEGGQLTEAVRRAPYSVIL
                     FDEIEKAHEDVFNMFLQILDDGRLTDNKGKTVDFKNTLIIMTSNIGSNYLLEAGGNIT
                     ETTNNLVMNEMKHRFKPEFLNRVDDIIMFKPLDQENIKKIIDIFMKDLKNRLKEKDIT
                     IEVTNSAKDVMVREGYDPVYGARPLKRYIGNTLETIIAKKLIAGDVYNGCTIVIDGKD
                     ENIEVLVK"
     gene            complement(6190..7617)
                     /locus_tag="ACGI5H_003195"
     CDS             complement(6190..7617)
                     /locus_tag="ACGI5H_003195"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897169.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HFG9698886.1"
                     /translation="MTNSFKKDDNRKKITVLFVVIAMTFMATLDSSIINVALPVLASK
                     LNVSLASIEWVIASYSIIICSTLLFFGRLGDIIGKSRVFQVGTILFTSASLLCGLSNS
                     LTLLIVCRFIQGIGASAYMANNHGIITELFPKESRGKALGILVTAVAIGNMVGPSVGG
                     FILSIFDWNVIFFINIPIGLIVIFLNTKFLPNSKKSSENMDKTGAILQFLGTTLFFSA
                     LISAQQTGLLNPYILIALLLSIIFIILFLILEKKHPQPLLDLEIFRNFKFSLNLICAL
                     TSFICIASSSILIPFYLQSTMKLPPIQAGLFMILSPLILAIFSPIFGNISDKIKSEKI
                     ILIGLLVMSFGFFLMSRLKESSALILFVIYISIISIGQAIFQPANNALIMSSCSRSKL
                     GVVGSINSLVRNLGQVIGITISTTLLYNFMSIKAGYRVNDYVINNDKIFVFGMRNVYI
                     IVTLVCLIGAILIGFYLFKYNKNEQ"
     gene            7758..8654
                     /locus_tag="ACGI5H_003196"
     CDS             7758..8654
                     /locus_tag="ACGI5H_003196"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729419.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AraC family transcriptional regulator"
                     /protein_id="HFG9698887.1"
                     /translation="MKDKNTYFNRKGQENFIDIFLKDDIKKGANFKRHWHEHLQIYYF
                     IDGIAYLECGLDNFKVVPGNIVIANSNELHYLESLSDNLKFYSIRIEPTFLFSNQVDL
                     LQTKYLAPLALNHIVFNNLIQNDSLILKCITTILDEYHNKEVGYELSIKANIYQLIVL
                     LLRSHIDKIYSEDEFIKRKYSLEKFECIFDLIEEKYMDKITLKELASHVNLSAHHFCR
                     TFKQITGKTTIDFINGIRLDKAIYYLKETDLNMTEIAMRCGFDSINYFSRLFKRNYNI
                     SPTKYRNEHKEVSNVILKEDMK"
     gene            9319..9459
                     /locus_tag="ACGI5H_003197"
     CDS             9319..9459
                     /locus_tag="ACGI5H_003197"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9698888.1"
                     /translation="MEKSNTTVTKKEKIEDIGMKLEHLLSEDITFYELLLEILYKEKE
                     EN"
     gene            complement(9456..9827)
                     /locus_tag="ACGI5H_003198"
     CDS             complement(9456..9827)
                     /locus_tag="ACGI5H_003198"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428913.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HFG9698889.1"
                     /translation="MESLGDRIANLRKELDINQKELATKVGITEASLSRYENNLREPK
                     SEIIVRLAKALETSTDYLLGVNDNTKISKEDKLIIENLSVSEKTKKLLEKIYSLEKED
                     REAIEKMIDNAYLKRFLKEEN"
     gene            10376..10633
                     /locus_tag="ACGI5H_003199"
     CDS             10376..10633
                     /locus_tag="ACGI5H_003199"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428911.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9698890.1"
                     /translation="MIIIRSQDKTNLMQINQIKIDGSQVYAVFESKIDTVKIGDYENN
                     TRAIQVLDNIQNFIENGTKYDYITSNKVRYNVNKIFQMPAK"
     gene            complement(10743..11423)
                     /locus_tag="ACGI5H_003200"
     CDS             complement(10743..11423)
                     /locus_tag="ACGI5H_003200"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897164.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VanZ family protein"
                     /protein_id="HFG9698891.1"
                     /translation="MIWTFYSFICVILPCLIYQIVVIKRKNLKVEKNVMIHLVWVYIF
                     LLYIYLALSKAGIGSIWDIGRYSGLFRIDEINLIPFDSVGILTYILNIIMFMPLGFLL
                     PLIWKNFRNIINVSLTGLGFSLAIELCQLFNLRATDIDDLMMNTLGAVLGYFIWVGVN
                     NLFNLIKKKDIFPSIYKNIIQDEIAITIDDDISKKITSLYKNEAIIYLILAVLGEFLL
                     FNWSIIPY"
     gene            11683..11982
                     /locus_tag="ACGI5H_003201"
     CDS             11683..11982
                     /locus_tag="ACGI5H_003201"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428907.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9698892.1"
                     /translation="MKWIKWYSITCICIFIVVAFYMFIFPNKIETIDTSSAYSFVEKK
                     VPNSAVYQGYKKNPVDGTTTIYYSYDNSTHIVRLSHPEDYSRKINWDKVSNIRFD"
     gene            12306..13961
                     /gene="ilvD"
                     /locus_tag="ACGI5H_003202"
     CDS             12306..13961
                     /gene="ilvD"
                     /locus_tag="ACGI5H_003202"
                     /EC_number="4.2.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729418.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004160 - dihydroxy-acid dehydratase
                     activity [Evidence IEA];
                     GO_process: GO:0009082 - branched-chain amino acid
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroxy-acid dehydratase"
                     /protein_id="HFG9698893.1"
                     /translation="MRSDIKKGIEGAPKRALMYGMGLTKEEIERPLIGIVNAQNEVIP
                     GHLHLDEIAEAAKNGVRMSGGLPLEFPAIGVCDGIAMGHVGMNYSLASRELIADSIEA
                     MAMAHGFDALVLIPNCDKIVPGMLMAAARLNIPSIVVSGGPMLPGKKNGKVYDFNSAM
                     EGVGACKDGTVSEEELEELAMNSCPGCGSCSGLFTANSMNCLTEALGMGIPYNGTAAS
                     HSGERKRIAKYAGMYVMELLKNDIKPRDILTIDAFKNAIAVDMAMAGSTNTVLHLPAI
                     AYESGIELNLDFFDEISEKTPCLTKLSPSGKHHIEDLHMAGGIPAIMNELSKINGINL
                     DCKTVTGKTIGENIRNCEIENEEVIHTLKNPYSNQGGLAILKGNLALNGAVVKKSAVA
                     EEMLVHEGPARVFNSEEEAVNAIFGKKINKGDVIVIRYEGPKGGPGMKEMLSPTSAVA
                     GMGLDKHVALLTDGRFSGATRGASIGHISPEAMEGGLIGLVEEGDIISINIPDKKLEL
                     KVDEVEIENRKLKFKPLEPKIKHGYLSRYAKLVTSANTGAVLK"
     gene            14305..14934
                     /locus_tag="ACGI5H_003203"
     CDS             14305..14934
                     /locus_tag="ACGI5H_003203"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428902.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HFG9698894.1"
                     /translation="MNREEKSKNSKEKIIQSAFSLFSSKGYDSTSTQDIINLSGLSRG
                     AMYHHFKTKEDILRSVTKELYSQMNNFLEHLVADDTLTANEKIIELVVHSANDYTRRK
                     MVHCSWLEKIPFALIEEVRNLNNVVAPNIAKIIKQGVENKEFSCEYPEELAEMLVFSI
                     DILLDPVLFKREYSEVCNRLDFLLFMLKKMDIPLIDEYGIQKFKDLFKQ"
     gene            14960..15772
                     /locus_tag="ACGI5H_003204"
     CDS             14960..15772
                     /locus_tag="ACGI5H_003204"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HFG9698895.1"
                     /translation="MFYNAKSCQMMIGSNTVNYIEFGSGKKTLIILPGLGDGLFPLHG
                     KIQAIAFAFRYKQFTKDYKVYVFSRKNQITEKYSTRDMAKDQADIMKKLGIMKAEVMG
                     VSQGGMIAQYLAIDYPELVEKLVLAVTSSKQNDTIQNVICSWIDMAKKQNYNDLMIDT
                     AKKSYSERYLKKYQLFIPFLGKVGKPKDFKRFIIQATSCIEHNAFSELNKITCPTLII
                     GGANDKIVGNNASFHLVEKIKKSEIFIYEGLGHATYEEAQDFNERVLEFLNK"
BASE COUNT         6464 a         1810 c         2415 g         5424 t
ORIGIN      
        1 aataaatacc tagtagagat taataattaa aaaataaaat actaccaaaa taaactcgat
       61 agtattttat ttaaatactt aaatacagaa acatatatag tatattttat acttcttttt
      121 tactatagat ttttgatgat ataaaatatg aaatcacaaa tagtaaaata gcaacaaatg
      181 gaagagaata tactagtgta ttaagtataa tttctataga aataggtgaa ctaatatttt
      241 ctaaaatact tttaaaaact aataaagcta gtgttggaac taaaaagcat aaaatcatta
      301 ataaacgagc tctttctgta ccaaatttat aaataagtgg tagaataagg ctaccaaaac
      361 atactgaaat tgataagatt agtgcattaa taagtagtgt ttcatttaat ataagtgtat
      421 ttttaaaata accaatagtt acactaacaa taagtgaaac aagaacacct ataaagctaa
      481 atattaacat agttaaatat ttacttaata caatatcatt gcgattaata ggcattgtaa
      541 gtacataact atcccattta ttcaaatcat catatgaaaa tgttgaaaca atcattgtag
      601 tacataaaac tataataaca cctataaagt tattaacatt tccatctcct aaagaagaca
      661 taaagccaaa cataatgatg aataaaagta taaactttat atttcctttc aaattaagta
      721 aatcttttaa aattagacct ttcattattt atcacctctc acataaaata acataatttc
      781 ttctatagac gtattatcaa caatacagtt tggatgtctt gagataaatc tatgcttatc
      841 tttaagaagt acttcatatc caaattggct tttacgataa tatgaataat cctctcttga
      901 aaggttatca aaatcactag gtttacattt taaaactccc atagtatcaa ttaattcatc
      961 cttattttca ctaaatacaa tttttccttt atgtataaat gtaatatagt ctgctatctt
     1021 atctaaatca cttgtaatat gtgaagataa gataatagag tgttcttcat cttgtataaa
     1081 atctaaaaat atatctagta tttcttcacg aacgataggg tcaagtgaac tagttgcctc
     1141 atctagtatt aataattttg gtttatgaga taaggctaca gcaatactaa gtttcatctt
     1201 attccccttt gaaaactcct taattaattt attgtctggt actctcaatt tttttaagta
     1261 gtctttaaat aatgtgtcat tccaattttt atagatttta ctcatgattt ttgaaacatg
     1321 gtcagtgttt aaattttcat gaaagttgct tccctcaaat acaaccccaa tttgctcttt
     1381 aatttctttt tcattttttt tactatcaag accaaagatt tctatatttc cactatcata
     1441 agatattaaa tttaaaattg cttttaatgt agttgttttt cctgcaccat tttcacctac
     1501 aaatcccatt acactccctt ttggtactga aaaagatata tcttgtaggc taaaatcttt
     1561 ataagtttta tttaaatttt ttatagttat tgcatccata cttatcattc tcctttatat
     1621 aataaaaata aaatatcttt taattcgtca tatgtaatat cactactttt tgctgtatca
     1681 actgcttttt gtaggtattc ttcaattaaa cgaaattgtt cttctttgac aaaatccatg
     1741 tttttactag atacaaaact gcctttacca gtaactgtct caataaatcc gtctcgttct
     1801 aaatcgctat atgctcgttt tgtagtaatt acacttattc taagttcctt tgccaatagt
     1861 ctcatacttg gaagagctga gccttctggt aactctccac ttataatcat acttttaatt
     1921 tgtgtagtaa tctgttcata tattggcttc ccactcgaat tactaataac tatattcaat
     1981 aagacacctc cttaaattgt atatatagta tatacacatt atataaatat atatataata
     2041 tgtcaactga ttttagaaaa aactaattac caatattata catttaataa atgtaatgta
     2101 ttttatgaaa gtctgccata ttaaatagat ttaaattttt ttaaaaaatt tataaatatt
     2161 gttcaaaaat cctgccaata aattggaaat actaaattaa aaaaataata aagtttagct
     2221 tatagctaaa taaaagttta cttataaggt gaactttttg cattttcagt tttgacatac
     2281 atattttttt gtaatatatt tatattatca attagagata aggagagtga gaagagatat
     2341 ttaatttgga taagacatta aaaaaggatt taaatcagga atatacagag agcaaaagtt
     2401 taattatgaa taaaagtaag tatatgaatg tttgttttaa gaattatatt aaagtagtag
     2461 aaggaatgta tactaagagg gatttaattc cattaaaatt aataaactct atggataaaa
     2521 ataataagat tagaaaaaca ttatatgaat tatcttgtga atttgaatat ccaaaaactt
     2581 ctttatcttc attgtttacg gagctgaaaa aaatggattt tttacaaaga gtgaaaaatg
     2641 gtgagtatat gataaatcca catatagcat ataaaggtag tagagctgat aaagaaagtt
     2701 tattagcaga atataatcag ataaaaagac ctaataaggt tagtaaataa ggaagaaggt
     2761 ttttatatga gtttaaaact tgatagaaat gttctacagt ggtttgacta tgtatttgag
     2821 aatgaaaaaa ctagtttgag acactataat tttaattgta cactaaagga gattagttct
     2881 accagtttga acaaagtagc ttttatttta gaaaaaaata actctaagta ctggaagctt
     2941 tattttgaaa taccagctga agttacttta aaacttaagc aaaacattca tcctttattt
     3001 agggaatata tatacgaaca aatatcactg tataacaata atcaaattta caattttgta
     3061 aattcaaaca tattaaaagt gtttaataat attgctattt atcaatataa tattttagaa
     3121 aatctataca ctattgattt taaaaagagt tttatagata aatgtcagta tttattaata
     3181 ggtgaaaaaa gacttataga tgaagacttg tatttaatag caaaatcaaa agaagtattc
     3241 gattttttta atttagatgg aacatttaat ttaacattga gtttcgatat acaaaaaaac
     3301 gagaatttac ttgatagtct tttagagctt agaaaatcaa taattataaa tgagagaatt
     3361 taatttattt ggatataata ttaaaatgga gggatttata tggacgtaga aaaaatgact
     3421 ttaagagttc aaaaaagttt aaatgaggct tataacgaag cagtaaaaaa tcataaccaa
     3481 caagtagatg taattcatct tttctcagca cttattaatc aagaggatgg attgatacca
     3541 aatataatcg aaaaaatgaa tatatcaatt gattctttga gaaatactgt aaactttgaa
     3601 attgataagc ttccaaaggt atatggagaa ggtgctgact cacaaggagt atcagctact
     3661 agaaaaataa atgaggtgct tataaaggca gagagtattt ctaaagaatt taaagattca
     3721 tatataagtg tagagcatgt tatgcttgca atgatggaaa cagaatcaaa atcagctgtt
     3781 ggtaaaatat taaaacaata taatataaat aagaataact ttttaaatat tttatcacaa
     3841 gtgagaggta gtcaaagagt agaaacacaa gacccagaag gcacatatga tgcacttgct
     3901 agatatggaa caaatttagt agatttagcc aagaaaaata aattagaccc tgtaattggg
     3961 agagatgaag aaataagaag gattataaga attttatcaa gaagaacaaa aaataatcct
     4021 gtattgattg gtgagccagg tgtaggtaaa actgcaattg tagaagggtt agcagagaga
     4081 atagtaagag gagatgtccc agaaggttta aaagataaga ttgtattctc acttgatatg
     4141 ggagctttaa ttgctggtgc aaaatataga ggtgaatttg aagaaagatt aaaggcagtt
     4201 ttaaaagaag ttcaaagttc tgatggaaaa attatactgt ttatagatga gattcatact
     4261 attgttggag ctggtaaaac agaaggttca atggatgcag gtaatcttat taaacctatg
     4321 cttgcaagag gtgaattgaa ctgtattggt gcaactactt ttgatgaata tagaaagtat
     4381 atagaaaaag ataaggctct tgaaagacgt tttcagcctg taattgcaga agaacctact
     4441 gttgaagata caatatctat acttagaggt ttaaaagaaa gatttgagat acatcatgga
     4501 gtaagaatac atgataatgc tattgtagca gcagcaaaac tttctcatag atatatacaa
     4561 gatagatttt taccagataa agcaattgat ttaattgatg aagctggagc tatgattcgt
     4621 agtgaaatag attcattgcc aacagaatta gatgttgtta gaagaaagtt atttacatta
     4681 gaaactgaaa gagaagcatt acttaaagaa aatgatgata aaagtaaatc aagattggat
     4741 gatattcaaa aagaaatagc agagttaaaa tctaaaaatg atgaaatgac agcaaaatat
     4801 gaaaaagaaa agagtcaaat attagatatt aaaaacttaa aggctcaatt agacgaagct
     4861 aaaggtaaag ctgaaaagta tgaaagagaa tatgatttca acaaagcagc agaggttaaa
     4921 tatggtgaaa tacctaagtt agaagaacaa ataaagcagt acgaagaaaa tatgaatgat
     4981 ggttctgaaa attctctttt aaaagaagaa gttactgaag aagaaatatc tagcattgta
     5041 tcaaagtgga caggtatacc agtaactaaa ctagttgaag gagaaagaga aaaattactt
     5101 aaactagaag atgaacttca taaaagagtt attggacaag atgaagcagt tacagcagtt
     5161 tcaaatgcag taatacgtgc aagagcagga ttaaaagatg aaagaaaacc aattggttca
     5221 tttattttct taggccctac aggtgttggt aaaactgaac ttgcaaaaac tcttgctaga
     5281 aatttattcg atagtgaaga taatataata agaatagata tgtctgaata catggaaaaa
     5341 catgctgtat caagactagt tggacctcct ccagggtacg tgggatatga agagggtggt
     5401 caacttacag aagcagttag acgtgctcct tattctgtaa tactatttga tgagatagaa
     5461 aaagcacatg aggatgtatt taacatgttc ttacagatat tagatgatgg tagacttact
     5521 gataataaag gtaagacagt agactttaaa aatactctta taataatgac ttctaatata
     5581 ggaagtaatt atctattaga agcaggagga aatataacag agactactaa caatttagta
     5641 atgaatgaaa tgaagcatag atttaaacct gagtttttaa acagagtaga tgatattata
     5701 atgtttaagc ctttagacca agaaaatatc aagaaaatta tagatatatt tatgaaagat
     5761 ttaaaaaata gattaaaaga aaaagatatt actattgaag ttacaaattc agcaaaagat
     5821 gttatggtga gagaaggata tgaccctgta tatggagcaa gacctcttaa gagatatata
     5881 ggaaatacat tagaaactat aattgcaaag aaacttattg ctggagatgt gtataatgga
     5941 tgtactatag ttatagatgg aaaagatgaa aatattgaag ttttagttaa ataataaaag
     6001 aatcagttga gcataatata ctaaatattt tgctcagctg atttttattt ataaactata
     6061 ggaaaagaaa tattttatca aattaataaa acatttttaa gtcaatatgt ccaaattaaa
     6121 tttaactcaa aggaagtatt ttagtaaatt tcttataata taatcataat ttgaatataa
     6181 ttataaaaac tattgttcat ttttattata tttaaataaa taaaagccaa ttaatattgc
     6241 acctattaag caaacaagtg taacaataat ataaacattt ctcattccaa atacaaatat
     6301 tttatcatta ttaatcacat aatcattgac cctatatcca gctttaatac tcataaaatt
     6361 atataaaagt gttgtagaaa tagtaatacc tataacttgt cctaaatttc ttacaaggga
     6421 atttatgctt cctacaactc ctagcttact tctagaacag cttgacatta tcaaagcatt
     6481 gttagcaggt tgaaatatag cttgtcctat tgatattatc gatatataaa ttacaaataa
     6541 aataagggca gaactttctt tcaatcttga cattagaaag aatccaaaac tcataacgag
     6601 aagaccaatt aaaataattt tttctgactt aattttatct gatatattcc caaatatagg
     6661 tgaaaaaatg gctaaaatca aaggtgatag tatcataaat aaacctgctt gaataggggg
     6721 aagtttcata gtactttgta aataaaatgg aattaaaata cttgatgatg caatacaaat
     6781 gaatgatgta agagcacaaa ttaaattcaa tgaaaattta aaatttctaa aaatttcaag
     6841 gtcaagaagc ggttgaggat gttttttttc taatatcaaa aataatataa taaaaataat
     6901 tgataataat agtgcaatta atatatatgg atttagtaat cctgtttgtt gagcactaat
     6961 tagagcacta aaaaataatg ttgttcctaa aaattgaagt atagcaccag ttttatccat
     7021 attttctgaa gattttttac tattaggaag aaattttgta tttaaaaaga ttacaataag
     7081 accgattgga atatttataa aaaatataac attccaatca aatattgaca aaataaatcc
     7141 tcccacagat ggtccaacca tatttccaat agcaactgca gtaactaaaa tccctagggc
     7201 ttttcctctg ctttcttttg gaaatagttc tgtgataatt ccatgattgt ttgccatgta
     7261 ggcagaagcg cctattcctt gaataaagcg gcaaactata agtaaagtta aagaattact
     7321 taatccacat agtaatgaag ctgatgtaaa gagaatagta cctacttgaa atactcttga
     7381 tttaccaata atatctccaa gtcttccaaa aaataatagt gttgaacaaa taataattga
     7441 gtaacttgct attacccatt caatagatgc tagagataca tttagtttgc ttgcaagaac
     7501 tgggagagca acatttataa tactagaatc taatgttgcc ataaaagtca tggcaatgac
     7561 tacaaataaa actgtgattt tttttctatt atcatctttt ttaaaagagt ttgtcatttt
     7621 tattacctcc ttattataat gactgcatta tgttaatgtt tacaatgata gttacatttt
     7681 atataatagc gatatgaaat aatgaataca ataactatat tgcttataat tagcactatt
     7741 ttgatgaggg gggaataatg aaggataaaa atacatattt taacaggaaa ggtcaagaaa
     7801 actttataga tattttttta aaggatgaca ttaaaaaagg agcaaacttt aaaagacatt
     7861 ggcatgagca tctacaaata tattatttta ttgatggtat agcatatctt gaatgtggat
     7921 tggataattt taaggtagtg cctggaaata ttgtaatagc aaacagtaat gaattacatt
     7981 atttagaaag cttatcagat aatttaaaat tctatagtat tcgtattgaa cccacattcc
     8041 tttttagtaa tcaagttgat ttgttacaaa ccaagtactt agcaccattg gctttaaatc
     8101 atattgtatt taataattta attcaaaatg attctctgat tttaaaatgt attacaacta
     8161 tacttgatga atatcacaat aaagaagttg gatatgagtt atctataaaa gctaatatct
     8221 atcaattaat agtactctta ttaagaagtc atattgataa aatatattct gaagatgaat
     8281 ttataaaaag aaagtattct ttagaaaaat ttgaatgtat ctttgatttg atagaagaaa
     8341 aatatatgga taaaattaca ttaaaagaac ttgctagtca tgtgaacttg agtgcacatc
     8401 acttttgtag aacatttaag caaataacag gtaagactac aatcgatttt ataaatggaa
     8461 tcaggcttga taaagctata tattatttaa aggaaacaga tttaaatatg acagaaattg
     8521 ctatgagatg tggctttgat agcataaatt attttagtcg cttatttaaa aggaattata
     8581 atatatctcc aactaagtat agaaatgaac ataaagaagt tagtaatgtt attttaaaag
     8641 aagatatgaa ataattcata aatatacttt atagaaaata tatattttta aatctttgag
     8701 tttttcttaa taaatattaa taaagtatag tacataaatg agtaagacta cttgtatagt
     8761 taaatgtgaa aatgagtatg aaagaatgta gtgtctatga aaagtatatt ttaatatgaa
     8821 actaaaattg gaaaaataag aatagcagaa aaaatgatta tattataaat cagttttttt
     8881 gagacatctg gcttagattc tgaaagatat ttaatcaaag aaataaaact attaaataag
     8941 caagtaaaca gctaaaatag tatgattttt atagaaaatt taaatccatc ctaaagaatt
     9001 aaaagaaagt caaataaata taaaaaaatt atatatttat aaaaaatttt ataataaaaa
     9061 tcatcctgaa aaatatataa aaatagaaaa aacatacaag attctacaat aatagatttt
     9121 tttgttatta ttacgagttt tttattgcaa ctgtagaata aaagtattat tatataatta
     9181 agataattat ctagggaaat tttggataat caaaatatat tttataaaat caaaatacaa
     9241 ttacataaac tttattaaaa atttgttggg aatttctgac taacattaag aacgtaagtt
     9301 tgttggggga tggtatatgt ggaaaagtca aacactactg ttacaaaaaa agaaaaaatt
     9361 gaagatatag gaatgaaatt agaacattta ttgagtgaag atattacttt ttatgaatta
     9421 ttacttgaga ttttgtataa agaaaaagaa gagaattaat tctcttcttt aaggaatctt
     9481 tttaaatagg cattatcaat cattttttct atagcttctc tatcttcttt ttcaagagaa
     9541 tatatttttt ctaagagctt ttttgttttt tcacttactg ataagttctc tatgattaat
     9601 ttatcttctt tgcttatttt tgtattatca tttacgccta ataaataatc tgttgatgtt
     9661 tctaatgctt ttgctaatct aactattatt tcacttttag gttctcttaa attattttca
     9721 taacgtgaca agctagcctc agttataccg actttagtag caagttcttt ttgatttata
     9781 tctaattctt ttcgtagatt tgctattcta tctcctaaac tttccatatg tacatcactc
     9841 cttaccgaaa ttataagtta ttttgataaa aagtaaaata aaattaccaa aaatataaaa
     9901 aaaaaaggtt aaaataataa aatatattga aaattaccat ttgtatatgt ataatatgaa
     9961 ttatacaaat ggtaatttga tgagaggtgg tatgttgaaa taagaaactg aattaattaa
    10021 taaatacata gaaagttttg aaaaccttta attgagatat aaacaatatg tacaaaattt
    10081 tttgcaagta aaattaccaa atgtataaaa taaatcagta gcatagataa ttttatgttt
    10141 taatacatta gattatttaa tttagttata atggtcaaaa atgcaatcta caaataaaac
    10201 aaagtattat caaaaaagta ttctttaaga aaatttttta ttagagatgt aattgatata
    10261 aataatcgta ttaaaaaata aaatactaag tttaaaaatt taaataatct ataaatcaat
    10321 tataaaatat tatttattag aaattaaaat gaattaagta aatggaggaa ttgatatgat
    10381 aataattaga agtcaagata aaactaattt aatgcagata aaccaaatta aaatagatgg
    10441 tagtcaagtt tatgcagtat ttgaaagtaa aattgatact gtaaaaatag gagattatga
    10501 aaataataca agagctatac aagtgttgga caatatacaa aacttcattg aaaatggaac
    10561 aaaatatgat tatataacat caaataaagt cagatacaat gttaataaaa tatttcagat
    10621 gccagctaaa tagtgagtgt gcattttaat ttaataacta aagcccactt tcttttgtag
    10681 tatgaaagag ggctttacat atttgtaaat atcgaagtac acttatttta tcaataaatt
    10741 atttaataag gtataatgga ccaattaaac aataaaaatt ctcctaaaac agcaagtatt
    10801 aaatatataa tagcttcatt tttgtaaaga gaggtaattt ttttgcttat gtcatcatca
    10861 attgtaatag caatctcatc ttgaataata tttttatata tagatgggaa aatatctttt
    10921 ttctttataa gattaaataa attatttaca cctacccata taaaatatcc taaaacagca
    10981 cctaatgtgt tcatcattaa atcatcaata tctgtagctc ttaagttaaa caattgacaa
    11041 agttcaattg ctaatgaaaa acctaatcca gttaatgaaa cattgataat atttctaaaa
    11101 tttttccaaa ttaaaggtag taaaaatcct aaaggcataa acataattat atttaaaata
    11161 tatgttaaga tgccaactga gtcaaaaggt attagattta tttcatcaat tctaaaaagc
    11221 ccactatacc ttcctatatc ccatatgcta ccaattccag ctttactaag tgctagatag
    11281 atatataata aaaaaatata tacccatact aaatgtatca ttacattctt ttcaactttc
    11341 aaattttttc gttttataac gactatttgg tatattaagc atggtaatat aacgcaaata
    11401 aatgaataaa atgtccatat cattttattt tgtccccttt caaatttatg tttttagttt
    11461 tataagtact atctttatat taaactgtaa gttttaaaaa tcttttaata aaatcttaaa
    11521 aatttattaa tttataaaaa tatattatta agattaaaaa atatatataa tcaaagtttc
    11581 tacaattata tagttaggga tataaaaatt ttatcgtatg cataaatatt ataaatatat
    11641 ggaaataata atagtatatt ttggtaaagt aggaggaatt ttatgaaatg gattaaatgg
    11701 tatagtatta catgcatatg tatttttata gtagtagctt tttatatgtt tatatttcct
    11761 aataaaatag aaactattga tacttcatct gcatatagct ttgttgaaaa gaaagtacca
    11821 aatagtgctg tgtatcaagg atacaaaaag aatccagttg atggtactac tacaatttat
    11881 tacagctatg ataattcaac tcatatagtt agattatcac atccagaaga ctattcaagg
    11941 aagattaatt gggataaagt ttcaaacatc agatttgatt aatctttaat atttataaaa
    12001 gtctatatat ctaaggcaaa tatattatta atcttattca tagttgagca ctttctatta
    12061 tagaagtgcc tcttctgatt tatatcataa aatattactc aacaatttgt aaaatatatt
    12121 agtttataaa atatattgaa aagataatat tatataatac gattgtgtaa gatattgata
    12181 aaaaatcgta ataaattttc attagtatat gctaatattt ttttacaatt ttcgtaatta
    12241 attaatagaa aaatatatta taataatatt atgaaaattt aaaaaagtaa gaaagaggta
    12301 atattatgag aagtgatata aaaaaaggaa tagaaggagc tccaaagaga gcgttaatgt
    12361 atggaatggg tcttactaaa gaagaaattg aaagaccatt aataggtata gtaaatgcac
    12421 aaaatgaggt gattcctggt catctgcatc ttgatgaaat agcagaagct gcaaaaaatg
    12481 gagtaagaat gagtggtggt ttgccattag aatttcctgc tataggggta tgtgatggta
    12541 tagctatggg gcatgtcgga atgaattatt ccctggcttc aagagaatta atagcagatt
    12601 caatagaagc tatggctatg gcacatggtt ttgatgcttt ggtacttata cctaattgtg
    12661 acaagatagt gccaggtatg ttaatggctg ctgcaagact taatatacca agtattgttg
    12721 tgagtggagg gcctatgctt ccaggtaaaa aaaatggaaa agtatatgat tttaactctg
    12781 caatggaggg tgttggagca tgtaaagatg gaacagtaag tgaagaagaa ttagaagagt
    12841 tagccatgaa ctcttgtcct ggatgtggtt catgttctgg tcttttcaca gcaaatagca
    12901 tgaattgttt aacagaagct ttaggcatgg gtataccata taatggtact gctgcgtcac
    12961 attctggaga aagaaaaagg atagcaaaat atgcaggtat gtatgttatg gagttactta
    13021 agaacgacat aaaacctaga gatattttaa caatagatgc ttttaaaaat gctatagctg
    13081 tggatatggc aatggctggt tctacaaata cagtacttca cttacctgca atagcttatg
    13141 aatcaggaat agagcttaac ttagattttt ttgatgaaat aagtgaaaaa actccttgtt
    13201 taacaaaatt aagtccaagt ggaaaacatc atattgaaga tttacatatg gcaggaggaa
    13261 taccagctat aatgaacgaa ctttcaaaga taaatggaat aaatttagat tgcaaaaccg
    13321 taacaggcaa gactataggg gaaaatataa gaaattgtga aatagaaaat gaagaagtaa
    13381 tacatacatt aaagaatcca tatagtaacc aaggtgggct tgcaatattg aaaggaaatc
    13441 ttgctctaaa tggagctgtt gtaaaaaagt cagcagttgc agaagaaatg ttagttcatg
    13501 aaggaccagc aagagttttt aattcagaag aagaagctgt aaatgctatt tttggtaaaa
    13561 aaataaacaa aggtgatgtt atagttataa gatatgaagg tccaaagggt ggtccaggaa
    13621 tgaaagaaat gctatctcct acatcagcag ttgcaggaat gggacttgat aagcatgtag
    13681 cacttcttac tgatggtcgt ttttcagggg caactagagg ggcatccata ggccatattt
    13741 ctccagaagc tatggaaggt ggtttaatcg gactagttga agaaggagat ataatttcta
    13801 taaacatacc agacaaaaaa ttagagttaa aagtagatga agttgaaata gaaaatagaa
    13861 aattaaaatt taaaccttta gaaccgaaaa taaagcatgg atacttaagt agatatgcta
    13921 aactggtaac atcagcaaat acaggagcag ttttaaaata gtagactata tttatgtaaa
    13981 ttagaaaaag ttaagaaaat attaattgga tatcttaggt gttatagcac taatgaggta
    14041 tcctttttat tttgtatgaa aaacatagca aaatcttgat tatctttgaa aacaatacat
    14101 ctctattata aggaatacga gtacagcata gagatgtatc ttttagacct tgttgaggta
    14161 atacaacttt ttaaaagttt gatgtggaat gcttttcgtt ccttctgaac tatgaagaaa
    14221 ttgaaagtaa gttaattctt gacataataa atattaaaat gtataataaa aaacaaacag
    14281 acagtctgtt tttaggaggg aaatatgaat agagaagaaa aaagtaaaaa tagtaaagaa
    14341 aaaattatcc aatcagcatt ttcactattt tcgtctaaag gatatgattc aacatctaca
    14401 caagatatta tcaatttatc tggtctatct agaggtgcaa tgtatcatca ctttaaaact
    14461 aaagaagata tactgagaag tgtcacaaaa gaactttact cacaaatgaa taatttttta
    14521 gagcatcttg ttgctgatga cacccttaca gcaaatgaaa aaataataga attggttgtt
    14581 catagtgcga atgattacac acgtagaaaa atggtacatt gtagctggtt agaaaaaatc
    14641 ccattcgctt taatagagga agttcgtaat ctcaacaatg tagttgcacc caatattgct
    14701 aagataatta aacaaggtgt tgaaaataaa gaattttctt gtgaatatcc agaggaatta
    14761 gctgaaatgc tcgtttttag tattgatatt ttacttgacc ctgtattatt taaacgtgaa
    14821 tacagtgaag tatgtaatag gttggatttt ttattattca tgttaaaaaa aatggatatt
    14881 cctctaattg atgagtatgg tattcaaaaa tttaaagatt tatttaaaca atgataatag
    14941 gaaaagtgag gaatagacta tgttttataa tgcaaaaagt tgtcaaatga tgataggaag
    15001 taatacagtg aattatattg aatttggtag tggtaagaag acactaatta ttttaccagg
    15061 attaggagat ggtttatttc ctttacatgg aaaaatacag gcgattgctt ttgcttttag
    15121 atataagcaa tttacaaaag attataaggt ttatgtattt agtagaaaaa atcaaattac
    15181 agaaaaatat tccacaaggg atatggctaa agaccaagca gatataatga aaaaacttgg
    15241 aattatgaaa gcagaagtaa tgggtgtttc tcaaggtgga atgatagctc aatatctggc
    15301 aattgattat cctgagttag ttgagaaact tgtgttggca gttacttctt caaagcaaaa
    15361 tgatactatc caaaatgtta tttgtagttg gattgatatg gcgaagaagc agaattacaa
    15421 tgatttaatg attgacacag caaagaaatc ctattctgaa agatatttaa aaaaatacca
    15481 attatttatt ccttttttag gaaaagtagg taaaccaaag gattttaaac gatttattat
    15541 tcaagcgacc tcttgcatag aacataatgc cttttccgaa ttaaataaaa taacatgtcc
    15601 aaccttaatt ataggaggtg ctaatgataa aattgttgga aataatgctt cttttcattt
    15661 agtagaaaaa attaaaaaaa gcgaaatatt tatctatgag ggattgggac acgctacata
    15721 tgaagaagca caggatttta atgaaagagt tttagagttt ttaaataagt aaacaccttt
    15781 gttaaaaata tacatatgaa gattggaaat ttaatgttaa aaatagaaac atgaaaatat
    15841 gcttaactgg tatttttact attcataacc aatttttgat acattatcta ctataaatac
    15901 aaatatagct tcaatgtgat tatatattgt tgtattggta aagcacttat acaaacagag
    15961 gaattttgta aattcatatt atacccacat ttgttaactt atgaaaatat aatcaaaatt
    16021 tttatgagct ttttatataa aaaatataat gtttgtatac aaaaatatta aagacatttt
    16081 agtaagtttt gtatataagc aaacatgtat ttt
//
LOCUS       DAYAOO010000093        15978 bp    DNA     linear   BCT 12-OCT-2024
DEFINITION  TPA_asm: Clostridioides difficile isolate ST8-SSI-h139-18
            SAMN40601845-rid21577343.denovo.094, whole genome shotgun sequence.
ACCESSION   DAYAOO010000093 DAYAOO010000000
VERSION     DAYAOO010000093.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN40601845
            Sequence Read Archive: SRR28438827
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 15978)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 15978)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-MAY-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-MAY-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002157583.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002157583.1
            Genome Coverage       :: 163x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/11/2024 16:19:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 4,038
            CDSs (total)                      :: 3,963
            Genes (coding)                    :: 3,930
            CDSs (with protein)               :: 3,930
            Genes (RNA)                       :: 75
            rRNAs                             :: 6, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 60
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 33
            CDSs (without protein)            :: 33
            Pseudo Genes (ambiguous residues) :: 0 of 33
            Pseudo Genes (frameshifted)       :: 7 of 33
            Pseudo Genes (incomplete)         :: 25 of 33
            Pseudo Genes (internal stop)      :: 11 of 33
            Pseudo Genes (multiple problems)  :: 8 of 33
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..15978
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN40601845-rid21577343.denovo.094"
                     /isolate="ST8-SSI-h139-18"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Denmark"
                     /collection_date="2018"
                     /collected_by="Statens Serum Institute"
     gene            248..397
                     /gene="rpmG"
                     /locus_tag="ACGI5H_003205"
     CDS             248..397
                     /gene="rpmG"
                     /locus_tag="ACGI5H_003205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014262850.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L33"
                     /protein_id="HFG9698896.1"
                     /translation="MRVKVTLACTECKQRNYNTTKNKKNNPDRIELQKYCRFCKKHTT
                     HKETK"
     gene            423..644
                     /gene="secE"
                     /locus_tag="ACGI5H_003206"
     CDS             423..644
                     /gene="secE"
                     /locus_tag="ACGI5H_003206"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421191.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_function: GO:0015450 - protein-transporting ATPase
                     activity [Evidence IEA];
                     GO_process: GO:0009306 - protein secretion [Evidence IEA];
                     GO_process: GO:0043952 - protein transport by the Sec
                     complex [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecE"
                     /protein_id="HFG9698897.1"
                     /translation="MAAQKNDGAKTKKRFSLFGYLKETKQELKRVTWPTKKELFKNTS
                     IVLTVVISCTILVWGIDTILSGALALLLK"
     gene            664..1206
                     /gene="nusG"
                     /locus_tag="ACGI5H_003207"
     CDS             664..1206
                     /gene="nusG"
                     /locus_tag="ACGI5H_003207"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421190.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0032784 - regulation of DNA-templated
                     transcription elongation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="transcription termination/antitermination
                     protein NusG"
                     /protein_id="HFG9698898.1"
                     /translation="MSELQEASWYVVHTYSGHENKVKATIEKAVKTRGMEDCIRQVVV
                     PTEEVVETTKTGKEKTRQRKVYPSYVLVKMIITDESWYVVRNTKGVTGFVGPGSKPVP
                     LSEDEVKAMGIDTTDPKVVNSDIDFEIGDTVKVSQGPFSGQIGNIEEIDLENREVKVC
                     INAFGKRTLFVIELEGIEKI"
     gene            1245..1670
                     /gene="rplK"
                     /locus_tag="ACGI5H_003208"
     CDS             1245..1670
                     /gene="rplK"
                     /locus_tag="ACGI5H_003208"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012158357.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L11"
                     /protein_id="HFG9698899.1"
                     /translation="MAKKVIGQIKLQIPAGKATPAPPVGPALGQHGVNIMGFTKEFNA
                     KTADQAGMIIPVVITVYQDRSFSFITKTPPAAVLIKKALNLKSGSGEPNKKKVAKMTS
                     AQVREIAELKMPDLNAASVEAAMSMIAGTARSMGVVIED"
     gene            1741..2439
                     /gene="rplA"
                     /locus_tag="ACGI5H_003209"
     CDS             1741..2439
                     /gene="rplA"
                     /locus_tag="ACGI5H_003209"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421188.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0015934 - large ribosomal subunit
                     [Evidence IEA];
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L1"
                     /protein_id="HFG9698900.1"
                     /translation="MAKKGKRYAGALQKVDRTKFYDASEALTLVSDIAGAKFDETVEA
                     HIKLGVDSRHADQQVRGAVVLPHGTGKTKRVLVFAKGEKAKEAEQAGADFVGAEELVQ
                     KIQGENWFDFDIVVATPDMMGVVGRLGRVLGPKGLMPNPKSGTVTFDVAKAIDEIKAG
                     KVEYRLDKTNIIHVPVGKVSFGGEKLTENFTALMDAIIKAKPAAAKGQYLRSITVASS
                     MGPGVKINPARTAE"
     misc_feature    2491..2619
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00557"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="ribosomal protein L10 leader region; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /db_xref="RFAM:RF00557"
     gene            2662..3168
                     /gene="rplJ"
                     /locus_tag="ACGI5H_003210"
     CDS             2662..3168
                     /gene="rplJ"
                     /locus_tag="ACGI5H_003210"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421187.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0015934 - large ribosomal subunit
                     [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L10"
                     /protein_id="HFG9698901.1"
                     /translation="MRKAIEIKSEVVSEIVEKLQKSSAAVVVDYKGLTVEEVTELRKQ
                     MREAGVDYKVYKNTLVRRAAKEVGIEQFNDELLVGTNAIAFGYDDPVAPARILKGFMD
                     SHPKMKLKMGIVEGAFYDESKIVEMANIPSREVLIAKLLGSLKAPVSNFAYLIDAIAK
                     KAEGQEEA"
     gene            3226..3591
                     /gene="rplL"
                     /locus_tag="ACGI5H_003211"
     CDS             3226..3591
                     /gene="rplL"
                     /locus_tag="ACGI5H_003211"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002842856.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L7/L12"
                     /protein_id="HFG9698902.1"
                     /translation="MTIEQILEAIENMKVLELNELVKAAEEKFGVSASAPVMVAGAAA
                     GGPAAEEKTEFDVVLTDVGSSKVGVIKAVREITGLGLKEAKEVVDNAPKTVKEGASKE
                     EADQIKEKLEAAGAKVEVK"
     gene            3982..4770
                     /locus_tag="ACGI5H_003212"
     CDS             3982..4770
                     /locus_tag="ACGI5H_003212"
                     /EC_number="1.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436172.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA];
                     GO_function: GO:0070403 - NAD+ binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family NAD(P)-dependent oxidoreductase"
                     /protein_id="HFG9698903.1"
                     /translation="MEKLQGKIAVVTAATKGIGLASAEILAKNGATVYLAARSEELAN
                     EVINKISAEGGCAKFVYFNAREEETFTSMIEEVVKKEGKIDILVNNFGSTNPSLDKDL
                     VTGDTDNFFDTVNTNLKSVYLPCKAAIPHMIKNGKGSIVNISSIGSVLPDLSRIAYCV
                     SKAAINSLTQNIATQYAKDNVRCNAVLPGLIATKAALDNMSPEFIKEFLKHVPLNRIG
                     EPDDIAKAVLFYASDDSSFITGDLLEVAGGFGLPTPQFADNILG"
     gene            5241..8957
                     /gene="rpoB"
                     /locus_tag="ACGI5H_003213"
     CDS             5241..8957
                     /gene="rpoB"
                     /locus_tag="ACGI5H_003213"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728819.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003899 - DNA-directed 5'-3' RNA
                     polymerase activity [Evidence IEA];
                     GO_process: GO:0006351 - DNA-templated transcription
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit beta"
                     /protein_id="HFG9698904.1"
                     /translation="MPHPVTIGKRTRMSFSKIKEIADVPNLIEIQVDSYEWFLKEGLK
                     EVFDDISPIEDYTGNLILEFVDYSLDDKPKYDIEECKERDATYCAPLKVKVRLINKET
                     GEIKEQEVFMGDFPLMTERGTFVINGAERVIVSQLVRSPGVYYAEERDKTGKRLISST
                     VIPNRGAWLEYETDSNDVISVRVDRTRKQPVTVLLRALGIGTDAEIIDLLGEDERLSA
                     TLEKDNTKTVEEGLVEIYKKLRPGEPPTVESASSLLNALFFDPKRYDLAKVGRYKFNK
                     KLALCYRIMNKISAEDIINPETGEVFVKAGEKISYDLAKAIQNAGINVVNLLMDDDKK
                     VRVIGNNFVDIKSHIDFDIDDLNIKEKVHYPTLKEILDGYSDEEEIKEAIKSRIKELI
                     PKHILLDDIIASISYEFNIFYNIGNIDDIDHLGNRRIRSVGELLQNQVRIGLSRMERV
                     IKERMTVQDMEAITPQALVNIRPVSAAIKEFFGSSQLSQFMDQTNPLSELTHKRRLSA
                     LGPGGLSRERAGFEVRDVHHSHYGRMCPIETPEGPNIGLINSLGTYAKINEFGFIESP
                     YRKFDKETSTVTDEIHYLTADEEDLFVRAQANEPLTEDGKFVNHRVVCRTVNGAVEMV
                     PESRVDYMDISPKQVVSVATAMIPFLENDDANRALMGANMQRQAVPLVRREAPIIGTG
                     IEYRAAKDSGAVVVARNSGIAERVTADEIIIKREDGNRDRYNLLKFKRSNSGTCINQT
                     PIINKGDQIIKGDVIADGPATDLGEVALGRNCLIAFMTWEGYNYEDAILINERLVKED
                     RLSTIHIEEYECEARDTKLGPEEITRDIPNVGDSAIKNLDDRGIIRIGAEVDSGDILV
                     GKVTPKGETELTAEERLLRAIFGEKAREVRDTSLKVPHGESGIIVDVKVFTRENGDDL
                     SPGVNELVRCYIAKKRKIKVGDKMAGRHGNKGVISRVLPEEDMPFMENGTPLDIILNP
                     QGIPSRMNIGQVLEVHLGLAAKTLGWYVATSVFDGANEYDIMDALEEAGYPRDGKLTL
                     YDGRTGESFDNRITVGYMYYLKLHHLVDEKLHARSTGPYSLVTQQPLGGKAQFGGQRF
                     GEMEVWALEAYGAAHILQEILTVKSDDVVGRVRTYEAIVKGENIPEPGIPESFKVLIK
                     ELQSLCLDVKVLTDEDQEIEVRESVDEDDTIGEFELDVVNHMGEVEESNIIEEIEDDF
                     AENAEDEDIENLEEFTEDDLFEEEIDFDSDDFDM"
     gene            8999..12484
                     /gene="rpoC"
                     /locus_tag="ACGI5H_003214"
     CDS             8999..12484
                     /gene="rpoC"
                     /locus_tag="ACGI5H_003214"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429485.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003899 - DNA-directed 5'-3' RNA
                     polymerase activity [Evidence IEA];
                     GO_process: GO:0006351 - DNA-templated transcription
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit beta'"
                     /protein_id="HFG9698905.1"
                     /translation="MFELNNFESIKIALASPEKIRQWSRGEVKKPETINYRTLKPEKD
                     GLFCERIFGPQKDWECHCGKYRRVRYKGVVCDRCGVEVTKSKVRRERMGHIELAAPMS
                     HIWYFKGIPSRMGLLLDMSPRSLEKILYFASYVVVDPGETGLNEKQLLTEKEYRTALE
                     KYGYTFTVGMGAEAVKTLLQNIDLEQQSKDLRAELKDSTGQKKVRTIRRLEVVEAFKK
                     SGNKPEWMILDAIPVIPPDLRPMVQLDGGRFATSDLNDLYRRVINRNNRLKRLLELGA
                     PDIIVRNEKRMLQEAVDALIDNGRRGRPVTGPGNRPLKSLSDMLKGKQGRFRQNLLGK
                     RVDYSGRSVIVVGPELKFYQCGLPKKMALELFKPFVMDKLVKEGYAHNIKSAKSIVEK
                     VKPEVWDVLEDVIKSHPVLLNRAPTLHRLGIQAFEPILVEGKAIKLHPLVCTAYNADF
                     DGDQMAVHVPLSVEAQAEARFLMLSVNNILAPKDGSPITTPSQDMVLGCYYLTIEAQD
                     GAKGTGMVFKDFNELLLAYYNKSVHLHALVKLKVTLEDGRSSLVESTVGRFIFNENIP
                     QDLGFVDRKENPFALEVDFLADKKSLGKIIDKCFRKHGNTETAELLDYIKALGFKYST
                     LGGITVAVDDMSVPEEKKVFIAEAEAKVDKYEKAYRRGLISDEERYEKVIETWTETTD
                     KVTDALMGGLDRLNNIYIMAHSGARGSKNQIRQLAGMRGLMANASGKTVEIPVKSNFR
                     EGLSVLEYFTSSHGARKGLADTAIRTAESGYLTRRLVDVSQDVIVREIDCGTEDTTEI
                     YAIKEGNEVIEEIYDRIVGRYTIDPILNPETGEVIVEADSMIQEDEAETIVALGIEKI
                     RIRTVLNCKTNHGVCSKCYGRNLATGKEVNIGEAVGIIAAQSIGEPGTQLTMRTFHTG
                     GVAGADITQGLPRVEELFEARKPKGLAVITEVSGRVEIDETGKRKEVNVIPEEGETQT
                     YVIPYGSRLKVKQGQMLEAGDPLTQGFINPHDIVRVNGVKGVQEYIVKEVQRVYRLQG
                     VDVNDKHIEVIVRQMLSKVKVEDPGDTDLLPGGYEDVLTFNECNKDAIDKGLRPAVAK
                     RVLLGITKASLATDSFLSAASFQETTRVLTEAAIKGKEDHLIGLKENVILGKLIPAGT
                     GMKKYRNIAVEKIED"
     gene            12773..13195
                     /gene="rpsL"
                     /locus_tag="ACGI5H_003215"
     CDS             12773..13195
                     /gene="rpsL"
                     /locus_tag="ACGI5H_003215"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012158364.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0015935 - small ribosomal subunit
                     [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S12"
                     /protein_id="HFG9698906.1"
                     /translation="MPTINQLVRKSRKALEKKSTAPALQKGYNSLNKKVTDASAPQKR
                     GVCTSVKTVTPKKPNSALRKVARVRLTNGIEVSAYIPGEGHNLQEHSVVLIRGGRVKD
                     LPGVRYHILRGTLDTAGVDKRRQSRSKYGAKRPKEAKK"
     gene            13319..13789
                     /gene="rpsG"
                     /locus_tag="ACGI5H_003216"
     CDS             13319..13789
                     /gene="rpsG"
                     /locus_tag="ACGI5H_003216"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013054923.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0015935 - small ribosomal subunit
                     [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S7"
                     /protein_id="HFG9698907.1"
                     /translation="MPRKGNIPKREVLPDPMYGSKVVTKLINNLMVDGKKGKSQRIVY
                     DAFAIVAEKTGEEALEVFNKAMDNIMPVLEVKARRVGGANYQVPIEVRPERRQTLGLR
                     WLVKYTRARGEKGMVEKLAKEIMDAANNTGASVKKKEDTHKMAEANKAFAHYRW"
     gene            13838..15904
                     /gene="fusA"
                     /locus_tag="ACGI5H_003217"
     CDS             13838..15904
                     /gene="fusA"
                     /locus_tag="ACGI5H_003217"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421177.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003746 - translation elongation factor
                     activity [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_process: GO:0006414 - translational elongation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor G"
                     /protein_id="HFG9698908.1"
                     /translation="MARKFPLERTRNIGIMAHIDAGKTTTTERILFYTGQTHKIGETH
                     EGASQMDWMEQEKERGITITSAATTASWKDHRINIIDTPGHVDFTVEVERSLRVLDGS
                     VAVFCAKGGVEPQSENVWRQAETYGVPRIAFVNKMDILGADFYNVVSMMKSRLNSNAV
                     PMQLPIGKEDSFIGIIDLLKMDAVIYKDDLGVEMEETDIPEDMKELAAEWREKLVESV
                     AETDEELMMKYLEGEELTIDELKVAIRKATIACEMNPVFCGTAYRNKGVQLVIDAVLD
                     YLPAPTDIPAIKGILADGEEAERHSSDEEPFSALAFKIMTDPFVGKLAFFRVYSGTLE
                     SGSYVLNATKNKRERIGRILQMHANTREEITKVYAGDIAAAVGLKDTTTGDTLCDPAN
                     PIILESMEFPEPVISVAIEPSSKAAQEKMGIALQKLAEEDPTFTVKTDQETGQTIISG
                     MGELHLEIIVDRLLREFKVEAKVGAPQVAYRETITQPVDVEYKYSKQSGGRGQYGHVK
                     IRVAPQEPGEGYKFTNKTVGGSVPKEYVGPVDMGIQGAMQSGIVAGYPVVDVAVELYD
                     GSYHEVDSSEMAFKMAGSMAFKDAMKKGNAVLLEPYFKVEVVTPEDYMGDVMGDLNSR
                     RGLIQGMEARSGAQVINAFVPLSEMFGYSTDLRSSTQGRATYTMIFDHYEQVPASVAK
                     KIAEGK"
BASE COUNT         6257 a         1989 c         3249 g         4483 t
ORIGIN      
        1 ctttactaaa ctgatggatt aaaaggaata acaaaaagag gggttatgct cctctttttt
       61 taacatagaa atacaaaaac attgacacag cataggattt tgtgataact tatacaaggt
      121 aatgattata ggaagttaat aatatcttga atactgtaga tttttaataa atacatattt
      181 taaagatatt atattcacat atattaacaa tatatattat tgtattacaa agttggaggt
      241 gtatcagatg agagttaaag taactttagc atgtacagag tgtaagcaaa gaaactacaa
      301 cactactaag aataagaaaa ataatccaga cagaatagaa ttacaaaaat attgtagatt
      361 ctgtaaaaag catacaactc ataaagaaac aaaatagttt tttataagga tgtgagtatg
      421 gaatggctgc ccaaaaaaat gacggtgcaa aaactaaaaa aaggtttagt ttgtttggat
      481 acttaaaaga aactaaacaa gaattaaaaa gagttacatg gccgacaaaa aaggaactgt
      541 ttaaaaacac aagtatagtt ttaactgtag ttatttcatg cactatatta gtatggggta
      601 tagacactat attatctggt gcactagcgt tattactaaa atagacgaaa agaggtaagt
      661 taaatgtcag aattacaaga agcaagttgg tatgtagttc atacctattc gggacatgaa
      721 aataaagtta aagctacaat tgagaaagca gttaaaacaa gaggtatgga agactgcata
      781 agacaagtag ttgttccaac agaagaagta gtggaaacta ctaaaactgg aaaagaaaaa
      841 actagacaac gtaaagttta tccaagttat gttttggtta aaatgataat aactgatgaa
      901 tcttggtatg tagtaagaaa tactaaggga gttacaggtt tcgttggacc tggttcaaaa
      961 ccagtgccat taagtgaaga cgaagtcaaa gctatgggga tagacacaac agaccctaaa
     1021 gtagtaaata gcgatattga ttttgaaata ggagatacag taaaagtatc tcaaggacca
     1081 tttagtggac aaataggtaa catagaagaa attgacttag aaaatagaga agtcaaagta
     1141 tgcataaatg catttggtaa aaggactcta tttgtaatag agcttgaagg tatagaaaaa
     1201 atctaatact atattataga aaaatctgag gaggtgcgct caaaatggct aaaaaagtta
     1261 taggtcaaat aaaattacaa atacctgcag gaaaggctac tccagcgcca ccagttggac
     1321 cagcattagg acaacatggt gttaatataa tgggattcac aaaagaattt aatgctaaaa
     1381 ctgcagatca agctggaatg ataataccag ttgttataac tgtatatcaa gatagatcat
     1441 tcagttttat aacaaaaact ccaccagctg cagttttaat taaaaaagca ttaaacttaa
     1501 aatcaggttc tggagaacca aacaagaaaa aagttgctaa aatgacttca gctcaagtaa
     1561 gagaaatagc tgaattaaag atgcctgact taaatgctgc atcagtagaa gctgctatga
     1621 gtatgatagc tggtactgct agaagcatgg gtgttgtaat cgaagactaa ttaaaagata
     1681 cacttttttt tataaagtgg gaggctagaa gccgaaatta accacgagga ggaaaataaa
     1741 atggctaaaa aaggtaaaag atatgcaggt gcattacaaa aagtagatag aactaaattt
     1801 tatgatgcat cagaagcatt aacattagtt tcagatatag ctggagctaa atttgatgag
     1861 acagtagaag cacacattaa attaggtgtt gactcaagac atgctgacca acaagtaaga
     1921 ggtgcagttg tattacctca tggaactggt aaaacaaaaa gagttttagt ttttgctaaa
     1981 ggtgaaaaag ctaaagaagc tgaacaagct ggtgctgact ttgtaggagc tgaagaatta
     2041 gttcaaaaaa tacaaggtga aaactggttt gactttgata tagtagttgc tactccagat
     2101 atgatgggtg tagtaggtag attaggtaga gtattaggac ctaaaggttt aatgccaaac
     2161 cctaaatcag gaacagttac atttgatgta gctaaagcta tagatgaaat aaaagctggt
     2221 aaagttgaat acagattaga caaaactaac ataatacacg ttccagtagg aaaagtatca
     2281 tttggtggag aaaaattaac tgaaaacttt actgcattaa tggatgctat aataaaagct
     2341 aaaccagctg ctgctaaagg acaatattta agaagtataa cagtagcttc ttcaatggga
     2401 cctggagtta aaataaaccc agcaagaaca gctgaataat aaaactgttg acacaggttg
     2461 acaaaaatgt tattatatca cttgtcaatg taaaaaagaa tagatttgcc gtagatagtg
     2521 ggtgcgaaag cttaatatcc cgccgaggtt ttagataaat tgagattact aaagcttttg
     2581 atgtctactt ttggcaacaa aagcttttta taatgttgcg gtaaatacta agcctatttg
     2641 gtgaaggagg tgcacatcta tatgagaaaa gctatagaaa ttaaatcaga agttgtttct
     2701 gagatagttg aaaagttaca aaaatcttct gctgctgttg ttgtagatta caaaggatta
     2761 acagttgaag aagtaactga gttaagaaaa caaatgagag aagctggtgt agattacaaa
     2821 gtatacaaaa atactttagt tagaagagca gctaaagaag ttggtataga gcaatttaat
     2881 gatgaattat tagttggaac taatgccata gcatttggat atgatgatcc agttgctcca
     2941 gctagaatat taaaaggatt catggattct catccaaaaa tgaaattaaa gatgggtatt
     3001 gtggaaggtg cattctatga tgaatctaag attgttgaaa tggctaacat accatcaaga
     3061 gaagttctta tcgctaaatt acttggtagc ttaaaagctc cagtatcaaa cttcgcatac
     3121 ttaatagatg caatagcgaa aaaggcagaa ggtcaagaag aagcttaatt gcttaactaa
     3181 aaaattataa atattaattt gaaataaaat tcggaggtgc taaaaatgac aatagaacaa
     3241 atattagaag ctatagaaaa tatgaaagtt ttagaattaa atgaattagt taaagctgct
     3301 gaagaaaaat tcggtgtatc agcttcagct ccagtaatgg tagctggtgc agctgctggt
     3361 ggaccagctg ctgaagaaaa aactgagttt gatgtagtat taactgacgt tggttcttca
     3421 aaagttggag ttataaaagc agttagagaa ataacaggat taggattaaa agaagctaaa
     3481 gaagtagttg acaatgctcc taagacagtt aaagaaggag cttctaaaga agaagctgat
     3541 caaataaaag agaaattaga agctgctgga gctaaagtag aagttaagta gtttctttaa
     3601 aaagataccc attgggtatc tttttttatt tataaaaaac tataaagaaa gtatttggaa
     3661 ttataaagaa agtattttta taaaataaaa aaaatttata taatagtact aaattaaggg
     3721 tatcatatat ggtgtaatgg tattttaatt taacattatt atcaaattaa aatataaaca
     3781 attgttgtaa tgtctgtata taaagtatat aattaaacta aaatgtaaaa ttttacattt
     3841 tagtttaaaa aaatacacga gtgtttataa ataaaatgta ataaataatt aattaacaaa
     3901 tataaatttt aaaataagtt agatatttag aaaaatcgaa atttgtagga tttaaaggac
     3961 atattcaagg aggagttaat aatggaaaaa ttacaaggaa aaattgcagt agttactgca
     4021 gcaacaaaag gtattggatt agcatcagca gagatattag caaaaaatgg agcaactgtg
     4081 tacttagcag ctcgttcaga agaattagct aatgaagtta taaataaaat aagtgcagaa
     4141 ggtggttgtg ctaagtttgt ttactttaat gctcgtgaag aagagacctt tacctcaatg
     4201 atagaagagg tagttaaaaa agaaggtaag atagatatac ttgtaaacaa ttttggttca
     4261 acaaaccctt ctcttgacaa agaccttgta actggggata cagataattt ctttgacaca
     4321 gtaaatacta atttaaaaag tgtgtattta ccatgtaaag cagcaattcc tcatatgata
     4381 aagaatggaa aaggaagtat agtaaatata tcaagtatag gttcagtatt acctgattta
     4441 tctagaatag cttactgtgt atcaaaagca gcaatcaact cattaactca aaacatagct
     4501 acacaatatg ctaaagacaa tgttagatgt aatgctgtac ttccagggct tattgcaact
     4561 aaagcagcat tagacaatat gtctccagag ttcataaaag aatttttaaa gcatgttcct
     4621 ttaaatcgta taggggaacc agatgatata gcaaaagctg ttctattcta tgctagtgat
     4681 gactcatcat ttataacagg ggatttactt gaagttgcag gaggatttgg tttacctact
     4741 ccacaatttg cagataatat attaggataa ttaaattact aatatgcaat gaaagcttat
     4801 gcattagtta tagtagaaat gatattttta taaaggccat agatataatt tatattggaa
     4861 aggtttgagg ttcaaaattc caagttaaat ttatttatgg tctttatttt gtatatttta
     4921 ataaattgta tatatttgta taaatgtaat tatttacaat cattttaata tggaattata
     4981 attaaatagg ggggatggta cttgtataaa attttttata gaaaattaga cctataaatg
     5041 aaaaatatgg attttatatt ggaaaattgt acataataca taatatatgc ttaaaataat
     5101 ttacaaaaaa tcaaaaataa tgcatagttt acatataaga taaaaaatat attgaaaaat
     5161 acttgacatt atgctaaaat tattagatgc gttagaatga actattgttt tatttttaat
     5221 tattgagagg tgaaaagtga atgccacatc ctgtcacgat aggtaaaaga actagaatga
     5281 gcttttctaa aattaaggaa atagctgatg tgccaaatct tatagaaatt caagtagatt
     5341 cctatgagtg gtttttaaaa gaaggtttaa aagaagtgtt tgatgatatt tcaccaatag
     5401 aagattatac tggtaatctt atattggaat ttgtcgacta ttctctagat gataaaccaa
     5461 agtacgatat agaagagtgt aaagagagag atgctacata ttgtgcacct ctaaaggtta
     5521 aggtaagact tataaataaa gaaacaggtg agataaaaga acaagaagtg tttatgggtg
     5581 acttcccttt aatgacagaa agaggaactt tcgttataaa tggagcagaa agagttatag
     5641 taagtcaatt agttagatct cctggtgttt actatgcgga agaaagagat aaaacaggta
     5701 agagattgat ttcatctact gtaattccta atagaggagc atggttagaa tatgaaacag
     5761 attctaatga tgtaatatct gtaagagttg atagaacaag aaaacaacca gttacagttt
     5821 tacttagagc tttaggaata ggaacagatg cagagataat tgacctttta ggagaagatg
     5881 agagattatc tgctacatta gaaaaagata atactaagac agtagaagaa ggtcttgtag
     5941 agatatacaa aaaattaaga ccaggtgaac ctcctactgt agaaagtgca tcatctttat
     6001 taaatgcttt attctttgac ccaaaaagat atgacctagc aaaagttggt agatataaat
     6061 tcaataagaa acttgcttta tgttatagaa taatgaataa aatttcagca gaagacataa
     6121 taaatccaga aactggagaa gtatttgtaa aagctggaga aaaaataagc tatgatttgg
     6181 ctaaagccat acaaaatgca ggtataaatg tagtaaatct actaatggat gatgataaaa
     6241 aagttagagt tataggaaat aattttgtgg atattaagtc tcacattgat tttgacatag
     6301 atgatttaaa cataaaagaa aaagtacatt atccaacttt aaaagaaatt ttagatggat
     6361 atagtgatga agaagaaata aaagaggcta taaaatcaag aattaaagaa cttataccaa
     6421 aacatatatt attagatgat ataatagctt caataagtta tgagttcaat atattctata
     6481 atataggaaa tattgatgat atagatcacc taggaaacag aagaataaga tctgtaggtg
     6541 aattgttaca aaatcaagtt agaattggtc tttcaagaat ggaaagagtt ataaaagaaa
     6601 gaatgacggt tcaagatatg gaagctataa cgcctcaagc gttagttaac ataagaccag
     6661 tttcagctgc aataaaagaa ttttttggta gttctcagtt atctcagttc atggatcaaa
     6721 caaatcctct atctgagtta acgcataaga gaagattatc agcccttggg cctggaggtc
     6781 tttcaagaga aagagctgga ttcgaagtgc gtgacgttca ccattcacac tatggtagaa
     6841 tgtgtccaat agagactcca gagggaccaa atatcggtct tataaactct ctaggaactt
     6901 atgcaaaaat aaatgaattt ggatttatag aatcaccata tagaaaattt gataaagaaa
     6961 catcaacagt tactgatgaa atacattatt taactgctga cgaagaagat ttattcgtaa
     7021 gagctcaggc aaatgagcca ttaacagaag atggtaaatt cgtaaaccat agagttgttt
     7081 gtagaactgt aaatggtgct gttgaaatgg ttcctgaaag tagagtagat tacatggata
     7141 tatctcctaa gcaggttgta tctgttgcca ctgctatgat acctttctta gaaaatgatg
     7201 atgccaaccg tgcccttatg ggagcgaaca tgcagcgtca ggcagtgcct ctagttagaa
     7261 gagaagcacc aattatagga actggtatag aatacagagc agcaaaagac tctggagcag
     7321 ttgttgttgc tagaaattct ggtatagcag aaagagtaac agcagatgaa ataattataa
     7381 aaagagaaga tggaaacaga gatagatata atctacttaa gtttaaacgt tcaaactcag
     7441 gtacttgtat aaatcaaaca cctataataa ataagggtga ccagataata aaaggtgatg
     7501 ttatagcaga tggtccagca actgatttag gagaagttgc acttggaaga aactgtctta
     7561 tagcattcat gacttgggaa ggttataact acgaggatgc tatattaata aatgaaagat
     7621 tagttaaaga agatagatta tcaacaattc atatagaaga atatgaatgt gaagctagag
     7681 atacaaaact agggccagag gaaataacta gagatatacc taatgttgga gatagtgcaa
     7741 ttaagaactt agatgacaga ggtataataa gaataggtgc agaagtagac tcaggtgata
     7801 tattagttgg taaagtaact ccaaaaggag aaactgaact tactgctgag gaaagattac
     7861 ttcgtgcaat atttggagaa aaggctagag aagttagaga tacttcactt aaagtgcctc
     7921 atggtgaatc tggtataata gttgatgtaa aagtatttac tagagaaaat ggagatgatt
     7981 tatctccagg agtaaatgaa ttagtaagat gctatatagc taaaaagaga aaaataaaag
     8041 ttggagataa aatggctggt cgtcatggta ataaaggggt tatctcaaga gtattacctg
     8101 aagaagatat gccattcatg gaaaatggaa caccactaga cataatactt aacccacaag
     8161 gtataccatc acgtatgaac attggtcagg ttttagaagt tcatttagga cttgctgcta
     8221 agacattagg atggtatgta gcaacatcag tattcgatgg tgctaatgag tatgacataa
     8281 tggatgctct tgaagaagct gggtatccta gagatggtaa attaacttta tatgatggta
     8341 gaacaggtga gtcttttgac aacagaataa ctgttggata tatgtactac ttgaaactac
     8401 atcacttagt agatgaaaaa ctacatgcaa gaagtactgg accatactca ttagttactc
     8461 aacagccact aggtggtaaa gcacaatttg gtggacaaag atttggagag atggaggttt
     8521 gggctctgga agcatatgga gctgctcaca tacttcaaga aatacttact gttaagtctg
     8581 atgacgttgt aggtcgtgtt agaacatatg aagctatagt taaaggtgaa aatatacctg
     8641 aaccaggaat cccagaatca tttaaggttc ttataaaaga acttcaaagt ttatgcttag
     8701 atgtaaaagt attgacagat gaagaccaag aaatagaagt aagagaatct gtggatgaag
     8761 atgatacaat aggtgaattt gagctagatg ttgtaaatca tatgggagaa gttgaagaaa
     8821 gtaatataat agaagaaatt gaagatgatt ttgcagaaaa tgcagaagat gaggatatag
     8881 agaatttaga agaattcact gaagatgatt tatttgaaga agaaatagat tttgatagtg
     8941 atgactttga tatgtaaatt taattaatgt aaatctcaaa tagaagggag agaactcctt
     9001 gtttgaatta aacaatttcg agtcgataaa aatagcattg gcttctccag aaaaaataag
     9061 acaatggtct aggggagaag ttaaaaagcc agaaactata aattaccgta ctttaaaacc
     9121 agaaaaagat ggtcttttct gtgaaagaat atttggacca caaaaagact gggagtgcca
     9181 ctgtggtaaa tatagaagag ttagatataa aggtgtagtt tgtgatagat gtggagtaga
     9241 agtaactaaa tcaaaagtaa gaagagagag aatgggacat atagagctag ctgctcctat
     9301 gtctcacatc tggtacttca aaggtatacc aagtagaatg ggacttttac ttgatatgtc
     9361 accaagatcg ttagaaaaaa tattatactt tgcctcatat gtggtagttg atccaggaga
     9421 gactggatta aacgaaaaac aattgcttac agaaaaagaa tacagaactg ctcttgaaaa
     9481 gtatggatat acttttactg taggaatggg tgctgaagct gtaaaaacat tactacaaaa
     9541 tatagattta gagcaacaaa gtaaagacct aagagcggag ttaaaagata gtacagggca
     9601 aaagaaagtt agaacaataa gaagattaga agttgtagag gcatttaaaa agtctggaaa
     9661 taaaccagaa tggatgattt tagatgcaat accagtaata ccaccagatt taagaccaat
     9721 ggtacaactt gatggtggaa gatttgcgac ttcagaccta aatgatttat atagaagagt
     9781 tataaataga aacaacagac ttaaaagatt attagagctt ggagctccag atataattgt
     9841 aagaaatgaa aaaagaatgc ttcaagaagc tgttgatgca ttgatagata atggtagaag
     9901 aggtagacct gtaacaggac ctggaaatag accacttaaa tctttatcag atatgttaaa
     9961 aggtaagcaa ggtcgtttcc gtcaaaactt acttggtaag cgtgttgact actcaggacg
    10021 ttctgttata gttgttggac cagaacttaa attttatcaa tgtggacttc caaagaagat
    10081 ggcattagaa ttattcaagc catttgttat ggataaatta gttaaagaag gttatgcaca
    10141 taatataaaa agtgcgaaat ctatagtaga aaaagttaag ccagaagttt gggatgtttt
    10201 agaagatgtt ataaaaagtc atccagttct tcttaaccgt gcaccgactc tacatagatt
    10261 aggtatacaa gcatttgaac caatcttagt tgaaggtaag gctataaaac tacatcctct
    10321 tgtatgtaca gcttataatg cagactttga tggtgaccaa atggcagttc atgtaccttt
    10381 atcagtagaa gcacaagcag aagcaagatt cttaatgctt tctgtaaata atatacttgc
    10441 tcctaaagat ggttcaccta taactactcc atctcaggat atggttttag gttgctatta
    10501 tctaacaata gaagcccaag atggagctaa aggaacaggt atggtattta aagactttaa
    10561 tgaactatta cttgcttatt acaataaatc agttcatcta catgcattag tgaaacttaa
    10621 ggtaacactt gaagatggaa gaagttcatt ggttgaaagt actgttggta gatttatatt
    10681 taatgaaaat atacctcaag acttaggttt tgtagataga aaagaaaatc catttgcact
    10741 tgaagttgat ttcttagcag ataaaaaatc tcttggtaaa ataatagata aatgctttag
    10801 aaaacacgga aatacagaaa cagctgaatt actagattat ataaaagctc taggatttaa
    10861 atattctaca ttaggtggca taacagttgc tgttgatgat atgagtgtcc cagaagaaaa
    10921 gaaagtattt atagctgagg cagaagctaa agttgataag tatgaaaaag catacagaag
    10981 aggtctaatc tctgatgaag aaagatatga aaaagttata gagacatgga cagaaacaac
    11041 tgataaagtt actgatgctc ttatgggtgg actagataga ttaaataata tatatataat
    11101 ggcacattca ggagccagag gttctaaaaa ccaaattaga cagctggcag gtatgcgtgg
    11161 tcttatggca aatgcatctg gtaaaacagt tgagatacca gttaaatcta atttccgtga
    11221 aggtttatca gtactagaat actttacatc ttcacatggt gccagaaaag gtcttgccga
    11281 tacagctata cgtacagctg aatctggata tttaacaaga agacttgttg atgtaagtca
    11341 agatgttatt gtaagggaaa tagattgtgg aacagaagat actacagaga tttatgctat
    11401 aaaagaagga aatgaagtta tagaagagat atatgataga attgtaggaa gatatactat
    11461 agaccctata ttaaatcctg aaactggaga agttatagtt gaggctgatt caatgataca
    11521 agaagatgaa gcagaaacta tagtagcttt aggaattgaa aaaattagga taagaacagt
    11581 tcttaactgt aaaactaatc atggagtttg ttctaagtgt tatggtagaa acttggcaac
    11641 aggaaaagaa gttaatatag gtgaagcagt tggtataata gcagctcaat ctatcggtga
    11701 gccgggtact cagcttacaa tgcgtacatt ccatactgga ggagttgcag gagctgatat
    11761 aactcaaggt ctaccaaggg ttgaagaatt atttgaagct agaaaaccaa aaggattagc
    11821 tgtaataact gaagtatctg gtagagttga aattgatgaa acaggaaaga gaaaagaagt
    11881 aaatgtaata ccagaagaag gcgagactca aacatatgta attccatatg gttctagatt
    11941 aaaagttaag caaggtcaaa tgctagaggc tggagaccct ctaacacaag gatttataaa
    12001 tcctcatgat atagtaagag taaatggtgt taagggagtt caagaatata tagttaaaga
    12061 agttcaaaga gtgtatagac ttcaaggggt tgatgttaat gataagcata tagaagttat
    12121 agtaagacaa atgctatcta aagtaaaagt tgaagaccca ggagatacag atttattgcc
    12181 aggtggatat gaagatgtat taacattcaa tgaatgtaat aaagatgcta tagataaagg
    12241 tctaagacca gcagttgcta aaagagtttt acttggtata actaaagcat ctcttgcaac
    12301 tgattcattc ttatcagcag cttctttcca agaaacaaca agagtattaa cagaggcagc
    12361 aataaaaggt aaagaagacc acttaatagg acttaaagaa aatgttatat taggtaagtt
    12421 aataccagca ggaacaggaa tgaagaaata tagaaatata gctgttgaaa aaattgaaga
    12481 ttaatagcat atagagtaaa gaaatcttga caaccattat ttgtggtgtt aaaatagtaa
    12541 agtgtgttgt ttaaaagtac actaagggct tgaacaagtt cttagtgact tttagatggc
    12601 aataaatgag aactaaaaag catcaagcta gaaaagtgct aatatcacat atttatgtgt
    12661 tatagacatt aaattgtaag taacgaatgt tacaatcagt cagtatgaat attcatattg
    12721 atgtagttgg cggtcactga taagatcgaa aatttggaag gaggtgcaga tgatgccaac
    12781 aattaaccaa ttagttcgta aaagtagaaa agcgctagag aagaaatcta ctgctccagc
    12841 attacaaaaa ggttacaact ctttaaataa gaaagtaact gacgctagtg ccccacaaaa
    12901 aagaggggtt tgtacttcag taaaaacagt tactcctaag aagcctaact cagctttaag
    12961 aaaagttgcc agagttagat taactaatgg tatagaagtt tctgcttata taccaggaga
    13021 aggacacaac ttacaagagc atagtgttgt tcttataaga ggaggaagag taaaagacct
    13081 tccaggggtt agataccata tactaagagg tactctagat acagcaggtg ttgataagag
    13141 aagacaatca agatctaaat acggtgcgaa gagacctaaa gaagctaaaa agtaaaaaca
    13201 attaatgatt gattatagtt cggtgcttta aatatatata tatttacggc atcacggcat
    13261 taaatgattt atgtcgagta cctatgattt aagttaaata attaaggagg gaagcgaaat
    13321 gccaagaaaa ggtaatattc caaaaagaga agttttacca gatcctatgt atgggagtaa
    13381 ggtagttact aaattaataa ataatctaat ggtagacgga aaaaaaggaa agtctcaaag
    13441 aatagtttat gatgctttcg caattgttgc tgaaaagaca ggagaagaag ctttagaagt
    13501 atttaataaa gcaatggata atataatgcc tgttttagaa gtaaaagcaa gaagagttgg
    13561 tggggcaaac taccaagtgc caatcgaagt tagacctgaa agaagacaaa cattaggttt
    13621 aagatggcta gtaaaatata ctagagctcg tggagaaaaa ggaatggttg aaaagctagc
    13681 taaagagata atggacgcag ctaacaacac tggagcttca gttaagaaaa aagaagatac
    13741 tcataaaatg gcagaagcta ataaagcatt tgctcattac agatggtagg atatatagat
    13801 atcttataaa attgaggata tcataaggag gataaccatg gctagaaagt ttcctttgga
    13861 aagaactagg aatataggaa tcatggctca tatagatgca ggaaaaacta ctactacaga
    13921 aagaatcctg ttttatactg ggcaaactca taaaatagga gaaactcatg aaggagcttc
    13981 tcaaatggac tggatggagc aagaaaagga aagaggtata acaataactt ctgccgctac
    14041 tactgcttca tggaaagacc atagaataaa cataatagat actcctggac acgtggactt
    14101 cacagttgag gttgaaagat ctctaagagt tcttgacggt tcagttgctg tattctgtgc
    14161 aaaaggtggg gttgagcctc aatcagaaaa tgtatggaga caagctgaaa cttatggagt
    14221 acctagaata gcttttgtaa ataaaatgga tatattaggt gcagatttct acaatgttgt
    14281 aagcatgatg aaatctagat taaattctaa tgcagttcct atgcaattac caataggtaa
    14341 agaagattca tttataggta taatagactt attaaaaatg gatgctgtta tatacaaaga
    14401 cgacctaggg gttgaaatgg aagaaacaga tataccagaa gatatgaaag aattagctgc
    14461 tgagtggaga gaaaaattag ttgaatcagt agctgaaact gatgaagaat taatgatgaa
    14521 ataccttgaa ggtgaagaac ttactataga tgaattaaaa gttgctataa gaaaagctac
    14581 tatagcttgt gaaatgaacc cagttttctg tggtacagct tatagaaaca aaggtgttca
    14641 gttagtaata gatgcagttt tagattactt accagcgcca actgatatac cagctataaa
    14701 aggtatatta gcagatggag aagaagctga aagacattct tctgatgaag agccattctc
    14761 tgcattagca ttcaaaataa tgactgaccc attcgttgga aaactagcgt tcttcagagt
    14821 ttattctgga acattagaat caggttctta tgttttaaat gcaactaaga ataagagaga
    14881 aagaattggt cgtatattac aaatgcatgc taatacaaga gaagaaataa ctaaagtgta
    14941 tgctggagat atagcagcag cagtaggatt aaaagatact actactggag acacattatg
    15001 tgaccctgct aatccaataa tacttgaatc tatggaattc cctgagccag ttatatctgt
    15061 tgctatagaa ccaagttcta aagcagctca agaaaaaatg ggtatagctc ttcaaaaatt
    15121 agctgaagaa gacccaactt tcacagttaa gactgaccaa gaaacaggac aaactataat
    15181 atctggtatg ggtgaattac acttagagat aatagtagat agattattaa gagaatttaa
    15241 agtagaagct aaagttggtg caccacaagt tgcatataga gagactataa ctcaaccagt
    15301 tgatgttgaa tacaagtact ctaagcaatc aggtggtaga ggacaatacg gtcacgttaa
    15361 gattagagtt gctcctcaag agccaggtga aggatacaaa ttcacaaaca aaactgttgg
    15421 tggatcagta ccaaaagaat atgttggtcc agttgacatg ggtatacaag gagctatgca
    15481 atctggtata gttgctggat atccagttgt agacgttgct gttgagttat atgatggttc
    15541 ttaccatgag gttgactctt ctgagatggc gtttaagatg gctggttcaa tggcattcaa
    15601 agatgctatg aagaaaggta atgcagttct tttagagcct tacttcaaag tagaagttgt
    15661 tactccagaa gattacatgg gagatgttat gggtgactta aactcaagaa gaggattaat
    15721 ccaaggtatg gaagctagaa gtggtgcaca agttataaat gcattcgttc cactttcaga
    15781 aatgtttgga tactcaacag acctaagatc ttcaactcaa ggtcgtgcaa cttacacaat
    15841 gatattcgat cactatgagc aagttccagc ttcagttgct aagaaaatag ctgaaggaaa
    15901 ataatttaaa aataattaat aatataaata taaaaaataa tcagctagat gagagatatc
    15961 tctcatctag cacaagat
//
LOCUS       DAYAOO010000094        15732 bp    DNA     linear   BCT 12-OCT-2024
DEFINITION  TPA_asm: Clostridioides difficile isolate ST8-SSI-h139-18
            SAMN40601845-rid21577343.denovo.095, whole genome shotgun sequence.
ACCESSION   DAYAOO010000094 DAYAOO010000000
VERSION     DAYAOO010000094.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN40601845
            Sequence Read Archive: SRR28438827
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 15732)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 15732)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-MAY-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-MAY-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002157583.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002157583.1
            Genome Coverage       :: 163x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/11/2024 16:19:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 4,038
            CDSs (total)                      :: 3,963
            Genes (coding)                    :: 3,930
            CDSs (with protein)               :: 3,930
            Genes (RNA)                       :: 75
            rRNAs                             :: 6, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 60
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 33
            CDSs (without protein)            :: 33
            Pseudo Genes (ambiguous residues) :: 0 of 33
            Pseudo Genes (frameshifted)       :: 7 of 33
            Pseudo Genes (incomplete)         :: 25 of 33
            Pseudo Genes (internal stop)      :: 11 of 33
            Pseudo Genes (multiple problems)  :: 8 of 33
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..15732
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN40601845-rid21577343.denovo.095"
                     /isolate="ST8-SSI-h139-18"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Denmark"
                     /collection_date="2018"
                     /collected_by="Statens Serum Institute"
     gene            359..1381
                     /gene="ccpA"
                     /locus_tag="ACGI5H_003218"
     CDS             359..1381
                     /gene="ccpA"
                     /locus_tag="ACGI5H_003218"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418918.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family transcriptional regulator CcpA"
                     /protein_id="HFG9698909.1"
                     /translation="MKMKGNITIKDVAKQAGVSISTVSRVINDSKPVTDEVKQKVLEV
                     IKETGYIPNPLARSLVTKKSQLIGVIVPEVSDSFVNEVLNGIEEVAKMYDYDILLANT
                     YSDKEQELKSINLLRAKQVEGIVMISWIVEQEHINYIQNCGIPATYISKTARNYDIYT
                     VSTSNEEATFDMTEHLIKKGHEKIAFIMTSKDDTVLEMERLAGYEKALSNNNIELDKS
                     LIKYGGTDYESGYNSMKELLDDGIIPHAAFVTGDEAAIGAINAICDAGYKVPEDISVA
                     GFNDVKIARMYRPKLTTVYQPLYDMGAVAIRMVIKLINKELIENKKIELPYRIVDRES
                     VTERKK"
     gene            complement(1504..1902)
                     /locus_tag="ACGI5H_003219"
     CDS             complement(1504..1902)
                     /locus_tag="ACGI5H_003219"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905301.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9698910.1"
                     /translation="MKKLDTESLEKMAKQKNIDKDKIEKMADSYKGKSENELMEELIK
                     IGKNLDGRDEVVSKFKAFLDENQRKKLDNIMEKISDAENQRDTKPAKTKKAKPTKGKS
                     NSPAPKNTPGSQQKKSKSLFKKTKKSNPHE"
     gene            2114..3025
                     /locus_tag="ACGI5H_003220"
     CDS             2114..3025
                     /locus_tag="ACGI5H_003220"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892884.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9698911.1"
                     /translation="MNNLLFLIGVIALSNGNISIFDDKNKSKGNNRVRKNKKNANDKL
                     SQSTHGNLRFDANDIKRGLRLMDLSEEDLEMGMEIITRTKKYMSRDERKILIKIESVL
                     DLVRGIKKLNNIDMVDTEDETDFFRKMDSDDKKNMMIKEIIDVFPEKRKNSVEKAIGM
                     KKKIDLFAELFLPDDFGEGGFSLSSLANINNLGSMNNLKLLGSLLRGDDSNNDDEDNN
                     DELNYEDEELDCEDKELDDDYDELTDEGEMEDNEDELVEDKNTGYENIENDEDIVYDE
                     ELYNINEQESEYNYNEKNTKTRAKKKR"
     gene            3140..3320
                     /gene="ssrS"
                     /locus_tag="ACGI5H_003221"
     ncRNA           3140..3320
                     /ncRNA_class="other"
                     /gene="ssrS"
                     /locus_tag="ACGI5H_003221"
                     /product="6S RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00013"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00013"
     gene            3503..4720
                     /gene="cdeC"
                     /locus_tag="ACGI5H_003222"
     CDS             3503..4720
                     /gene="cdeC"
                     /locus_tag="ACGI5H_003222"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437985.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exosporium morphogenetic protein CdeC"
                     /protein_id="HFG9698912.1"
                     /translation="MQDYKKNKRRMMNQPMSTMNEEEVYTDEINSEDMRGFKKSHHHN
                     GCNTDNKCECHDDCNPCNPCNPCKPNPCNPCKPNPCDDNCGCHDNCKCDCEPCEMDSD
                     ECFENKCGPECCNPISPRNFSVSNAVPFAIEANRIFDTMQFQTFTDATGPNGEPLTFE
                     TEVVEVFGSVPSAGQASVTIEKICLSNDGIVIDTGMTTLEDFDLDPLGDIVGRNCETT
                     FEFAVCGERNAECCRQGKGKSVAYKQRGLTVAVRNLVLELRGRCGCTEFVALAFPAVR
                     AGGGCKRRVDYVEFTFNTLSAPICLPADGRAVTLRQEYQTNLTVDCIGKSILKLECNE
                     CCEPFYELIIPNDIDLVLCLQETVSTLISEQIVVLASPNPIQPRLVDTFSKVCDFSQC
                     GPNHGSGKPSCHR"
     gene            complement(4821..6143)
                     /locus_tag="ACGI5H_003223"
     CDS             complement(4821..6143)
                     /locus_tag="ACGI5H_003223"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888874.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_process: GO:0009252 - peptidoglycan biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide biosynthesis protein"
                     /protein_id="HFG9698913.1"
                     /translation="MKVPYLVLSTVILFISNFIVRIFGFLYKIFLSRALGETGLGIYH
                     MIFNFLMICLAVTTTGIPTALSCLVAKRKALNDRHNTNALFISTLYISFFVALIISIV
                     ASFNSSFLSLKFLKDAKLNLFILAVCPAIVIITLSNVLRGYYYGIKNVKIPAIGQIIE
                     QIGKILFVFLLVMYINNKSMNCYIALLGISIGELSNIIFMLICLWRDSSFDNRYIISI
                     KDFYNSSMETLKMSIPITCNRMSNILLQSISSMMIPSRLALSGMTYQQSLSMYGIVSG
                     MVMPFIFLPFTVGSALIVNLIPTISQEMALRKRKSVIKKIKYSILLTLFVGILSSIFF
                     YFFGKDLCILVFKNTLAGEYLKAMFLVPLFMSLNQTLSGILHSIRKELASSINTITGM
                     LIQLIALYVFLPIPGLNIYAYIYTMTIVSIFTCLLHTIVLFKSLKSIR"
     gene            complement(6194..6988)
                     /locus_tag="ACGI5H_003224"
     CDS             complement(6194..6988)
                     /locus_tag="ACGI5H_003224"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896027.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004401 - histidinol-phosphatase activity
                     [Evidence IEA];
                     GO_process: GO:0000105 - L-histidine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="histidinol-phosphatase HisJ family protein"
                     /protein_id="HFG9698914.1"
                     /translation="MFYDYHMHSSFSTDGKSTMEEMVKKSIELGLEEICFTDHVDYDV
                     YADDSFSIVYEDYFKSLETLQSKYKDKISIKKGIEFGVQTQLMDTYKKEAHQYPLDFI
                     ICSIHAIDTMDLYLGNYFKDKTQHEVYENYYLYLYNIVKNYKDYSVLGHLDLIKRYAP
                     YDTILDDRLFSDIIEETLKQAIYDGKGIEINTSCYRYNLPDLTPSKYILQMYKDLGGE
                     IITTGSDSHHISQVACEFDYIYSLLKNMGFKYVSKFNKLKPEFIKL"
     gene            7098..8543
                     /locus_tag="ACGI5H_003225"
     CDS             7098..8543
                     /locus_tag="ACGI5H_003225"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888876.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PLP-dependent aminotransferase family protein"
                     /protein_id="HFG9698915.1"
                     /translation="MEKYRIDLNEKKSTKYIQIFNHIKELIINKELVEHEKLPPIRKL
                     SNFLQVNNTTIVKVYELLENEGYVYKIIGSGTFVSSLNSYKSGIDNRKNKIIVQREDL
                     IHFDNGNPSNDMFPIDSFKNAVNMALSKDGSSIFEYDEGLGSEELREKMVEYLSDGNI
                     KTTKENIQIISGAQQGIDIVCKGLISYSDVVFMEEPSYNGAIEVFKSRGAKIISIPML
                     DDGIDIGILKLKLEKIKPRLIYIMPNFQNPTGISYSTYKKKKLIELAEEHDFYIIEDD
                     FISDFVFESKDNRTIRSYDDKNRVVYIKSFSKILMPGLRIGIVEMPNELLKKVLWAKY
                     SSDISTPGLIQKSMYYYMNNFDWKNYLSHIEKIYTDKYKLAKNLINDKLSGKLKVRKS
                     CGGINFFLELPRGYTSQAFTNFMLNKGVSMLPGTYFFDNLVDDRFFRINIARPSMEEL
                     EKGISIISDNIDEFFCEYKNKLDIKSNKLFY"
     gene            8572..8781
                     /locus_tag="ACGI5H_003226"
     CDS             8572..8781
                     /locus_tag="ACGI5H_003226"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418943.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF896 domain-containing protein"
                     /protein_id="HFG9698916.1"
                     /translation="MFDKKKLDRINELAKKNKEGILSADEIKEREILRKEYLENFRAH
                     FRSRLDSVKVVSPEEYEQYMKNNKN"
     gene            8801..10195
                     /locus_tag="ACGI5H_003227"
     CDS             8801..10195
                     /locus_tag="ACGI5H_003227"
                     /EC_number="3.4.11.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861085.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004177 - aminopeptidase activity
                     [Evidence IEA];
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase"
                     /protein_id="HFG9698917.1"
                     /translation="MNLKYEFKNAWDFERKENTIEQIMQYSSNYMEFLSKSKTERLSV
                     KEIIKLAKENNYISIDEAMEKGSISCGDKIYVINKEKAVALFVIGKNYIEKGMKIIGS
                     HIDSPRLDLKPNPLYQESNLGFFKTHYYGGIKKYQWTAIPLALHGIVILNDGTKVDIS
                     IGEEDSDPVFCVTDLLIHLAGDQMQKKLSEGISGEALNILIGNMPLEDEEKEPITANI
                     LKILNEKYNIVEEDLLSAEIEVVPAGKARDLGLDRSMVLGYGHDDRVCSYAAVKAILE
                     TEQPEFTSVALCVDKEEIGSKGNTGMHSKFFENTVAELIALEGDYCDIKVRRALANSK
                     VLSADVSAGYDPNFGEAYEKRNSAYMGNGVVLTKYTGSRGKSGCNDANAEFMSEVKRI
                     FNKGNVIWQTAELGKVDQGGGGTIAHILANQGAEVIDCGVGVLNMHAPHEIVSKVDIY
                     EMYKGYKAFFNINL"
     gene            10435..11187
                     /locus_tag="ACGI5H_003228"
     CDS             10435..11187
                     /locus_tag="ACGI5H_003228"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896033.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HFG9698918.1"
                     /translation="MDEKRQKKEMDLEVNSFVPLYQQLYDNIKKQIASGIYKPGDKLP
                     SEGDLCKEFNISRITVRNALNELVKEDILCKKRGKGTYVTIPERIEATCAGNSFTNSC
                     HRINAKPSTKIISVLIKKADKQVAEALSIELEEKVICIKRLRLIDEVPVIFEVDYFRI
                     DYMFLLKEELEDKSLMEVISNNISTLPKRVENIFEVKHSNKEYSDHLKCASNMPLLKV
                     RQSVYTENNDVLYYNEQFIRSDKYKYAVSAEI"
     gene            11213..11626
                     /locus_tag="ACGI5H_003229"
     CDS             11213..11626
                     /locus_tag="ACGI5H_003229"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896035.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:1902495 - transmembrane transporter
                     complex [Evidence IEA];
                     GO_function: GO:0016301 - kinase activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA];
                     GO_process: GO:0016310 - phosphorylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HFG9698919.1"
                     /translation="MKKIILASHGDFSKGLLNAVKMIVGDLADCVSSYGLYPGQSASD
                     FALELEKTISEDKECEYIILSDLYGASVCTAMLRLTNLHNVRLFSGMNLNMVLELLTR
                     FSDELTVEDIDQLVEESRRGIQSVTLQIKEEEEVF"
     gene            11630..12373
                     /locus_tag="ACGI5H_003230"
     CDS             11630..12373
                     /locus_tag="ACGI5H_003230"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888880.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BtpA/SgcQ family protein"
                     /protein_id="HFG9698920.1"
                     /translation="MKKKGILSVFKSKKPIIAMIHLKGDTPEDIFERAKKEITIFEEN
                     GVDGIMLENYYGNYYDLERILEYVSKANLSIPYGVNCLNVDTMGFELATKYNASYIQV
                     DSVVGHVKPRDEATLEEFFKLQRSKCPAYLIGGVRFKYQPVLSENDVEEDLKIGMTRC
                     DAIAVTENATGQETSMEKIELFRKNLGDFPLVIAAGVTLENAKKQLKLGDMAIIGSYF
                     KDNYKDFGDVSVEHVKTFMDEIKKIREEL"
     gene            12373..12843
                     /locus_tag="ACGI5H_003231"
     CDS             12373..12843
                     /locus_tag="ACGI5H_003231"
                     /EC_number="2.7.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888881.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HFG9698921.1"
                     /translation="MIKLVRVDHRLIHGQVAFTWTKFLSTDCILIASDDLLKDELRMA
                     GLKMAKPSNVKLVMKSIADSIKALNSGVTDKYNLLILCESVEDVYRLAKEVKAIKSIN
                     LGGTKSDDNRENISKAVHVSKDDIKMIKELDSEGVNVFVQLVPDDDATNVMKLI"
     gene            12860..13618
                     /locus_tag="ACGI5H_003232"
     CDS             12860..13618
                     /locus_tag="ACGI5H_003232"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888882.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS
                     mannose/fructose/sorbose/N-acetylgalactosamine transporter
                     subunit IIC"
                     /protein_id="HFG9698922.1"
                     /translation="MEFTQVILITLIAFFAYMHSFVGSTMHNRPIVVAPLVGLALGNL
                     HTGIVIGSTLELVFMGAFPVGASNPPDFVSGSIIATAFVILTGQDVSAAVVLAVPIAT
                     LVLLIDNFLMTVVLTWGAHIADRYAEEGNIEGVERVQLLFGIGNKLILAIIVGIGFSL
                     GVPVIEKILSFIPSYVTHGMDVAAGVIPAIGFAMLARMMLNKKTVAFLLLGFILVAYL
                     NITVTGVALFGLAIALIYVNFVGEKEVIVDDNEF"
     gene            13602..14444
                     /locus_tag="ACGI5H_003233"
     CDS             13602..14444
                     /locus_tag="ACGI5H_003233"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418955.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:1902495 - transmembrane transporter
                     complex [Evidence IEA];
                     GO_function: GO:0016301 - kinase activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA];
                     GO_process: GO:0016310 - phosphorylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system mannose/fructose/sorbose family
                     transporter subunit IID"
                     /protein_id="HFG9698923.1"
                     /translation="MTTSSKKLETISPDSKITRKDFWKCFRRSLTLDSSWNYERMQNI
                     AYAYMMAPIIRRLYKDDKEKKSKALKRHLEFMSVTPHISTLLVGISGAMEEENAKNKE
                     FDANSINAVKSSLMGPVSGIGDSFFWGTLKLIAAGVGIALASQGNIMGPILFLLIINV
                     PHFIIRYICLDKGFKYGTQFFKDVSGSSIVSKVMEAASMLGLMVIGGMTASNVMLKLS
                     VNVGSGEWAEPIQTYLDQIMPCMLPAMIFGIMYWLLGKKVKTTTILISVMIICIVLAA
                     IGVV"
     gene            complement(14604..15509)
                     /locus_tag="ACGI5H_003234"
     CDS             complement(14604..15509)
                     /locus_tag="ACGI5H_003234"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892888.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="selenium metabolism-associated LysR family
                     transcriptional regulator"
                     /protein_id="HFG9698924.1"
                     /translation="MDFKQLEVFVAVAKHQSFSKAARELFLTQPTVSAHIQNLERELE
                     TVLINRSNKVITLTKSGEILYEHAIYILNNCKRAIYDIKEYSGKIEGIIDIACSSIPE
                     TYILPDFMKSFSMSYPDVKFSISHYDSQYAISEILNERISFGLVGSKINNPQIEYLDL
                     LDDELVLITPSDFKIDNKNNCIDIGELAYLNFIMRKEGSGTRNLILNTLSKNNFPVSK
                     LNVIAHVESNEAIKEMVRLGLGVSFISYISAIDYLNAGKIKCYKIKDVDFTRKFFFIY
                     SKKKTFSPLEDKFLNRLCEYFEIII"
BASE COUNT         6126 a         1775 c         2737 g         5094 t
ORIGIN      
        1 agattgctgg agagacattg acataatgtc atggatacct ttcttaatat tattgctaat
       61 aacttgttca tgtggtggat tctttgatgg tgaagtaggt tgcggctgct aatacttaaa
      121 tcattagaat aaaaaaatgc tggtatttta taccagcatt tttttatttt attttttaat
      181 atgatttaaa ttaagaatga atattattaa atttgttgaa tatagggtat aatataaaat
      241 ataatgtatt taaatgtact tgcttttatg gtaaaataaa aacttatata aatgtagtta
      301 aaataggaac cttcaaaaat ttggttcagt tttagataaa tttagtaaaa taaggaggat
      361 gaagatgaaa ggcaatataa cgataaaaga tgttgctaaa caagcaggag tgtcaatatc
      421 tactgtatct agagttataa atgattcaaa acctgtaact gatgaagtca aacaaaaagt
      481 tttagaggtt ataaaagaga ctggatatat accaaatcca cttgctagaa gcttagtaac
      541 aaagaagagt caattaatag gggtaatagt tccagaagtt tcagattctt ttgttaatga
      601 ggtgttaaat gggatagaag aggttgctaa aatgtatgac tatgatattc ttttagcgaa
      661 tacatactct gataaggaac aagaacttaa gagtataaat ctattgagag caaaacaagt
      721 ggaaggtata gttatgattt catggatagt tgaacaagaa catatcaact atatacaaaa
      781 ttgtggaata ccagcgacat atataagtaa aactgctaga aattatgata tatatacagt
      841 aagtactagc aacgaagaag ctacttttga tatgacagag catcttataa agaaaggtca
      901 tgaaaagata gcttttataa tgacgagtaa agatgatact gttttagaaa tggaaagact
      961 tgctggttat gagaaagcac tttcaaataa caatatagaa ttagacaaga gtttgattaa
     1021 gtatggtgga actgattatg agagtggata caatagtatg aaagaactat tagatgatgg
     1081 aataatacct catgcggctt ttgtaacagg tgatgaggct gccataggtg ctataaatgc
     1141 tatatgtgat gctggatata aggttccaga agacatatct gttgcaggat ttaatgatgt
     1201 taagatagct agaatgtata gacctaaact tactacagta tatcaacctc tatacgatat
     1261 gggagcagta gcaataagaa tggttataaa gttaataaat aaggaattaa ttgagaataa
     1321 gaaaatagaa ttaccttata gaattgttga tagagaaagt gttacagaaa gaaaaaaata
     1381 aaactattaa aatcaatcag gtagtgccta aggcactacc tgatttttta tgtcaataat
     1441 atcaaattta ataatagatt aactaaaaat aattatctaa ttacttaaat agtttatttt
     1501 tatctattca tgagggttag actttttagt tttcttaaat aaacttttag attttttttg
     1561 ttgactacct ggtgtatttt ttggtgcagg tgaatttgac ttacctttag taggtttagc
     1621 cttcttagtt ttagctggtt tagtatctct ttggttttct gcatctgaga ttttttccat
     1681 tatattatcc agttttttgc gttgattttc atctaaaaat gctttgaatt ttgatactac
     1741 ttcatctctg ccatctaggt tcttacctat ttttataagt tcctccataa gttcattttc
     1801 tgattttcct ttgtaactat cagccatctt ttctatttta tccttgtcaa tatttttttg
     1861 tttagccatt ttttctaatg actctgtatc taattttttc ataaaaaaac ccctttctat
     1921 aaatatatat tgaattatat tcatactatt tatatataga aataatattg aagtggtgaa
     1981 ttgtgagtga tatataatat aaataaaaat tcttatagat aatatatatg cactgagctt
     2041 taaaaatgga acattaaaat atgaaaaaca tactttaata tagggcaatt atataatata
     2101 agggggaatt gtcttgaata acttactatt tttgattgga gtgattgcat tgagtaatgg
     2161 taatatctct atatttgatg ataaaaataa atcaaaagga aataatagag ttagaaaaaa
     2221 caaaaaaaat gcaaatgata aactttcaca gtctacacat ggcaatttaa ggtttgatgc
     2281 aaatgatata aaaagaggtt taaggctcat ggatttaagt gaagaagatt tagaaatggg
     2341 aatggaaata ataacaagaa ctaaaaaata catgtcaaga gatgaaagaa aaatactaat
     2401 aaaaatagaa agtgttttag atttagttag aggaataaaa aaattaaata atatagatat
     2461 ggtagataca gaagatgaaa cggatttttt cagaaaaatg gatagtgatg ataaaaagaa
     2521 tatgatgata aaggaaatta tagatgtatt cccagaaaaa agaaaaaatt cagttgaaaa
     2581 agctatagga atgaaaaaga agatagattt atttgcagaa ttatttttac cagatgactt
     2641 tggtgaaggt ggatttagtt tgagctcttt ggcaaatata aacaatcttg gtagtatgaa
     2701 taatctcaaa ttgttaggaa gtcttttaag aggtgatgat agtaataatg atgatgaaga
     2761 caataatgat gagttaaatt atgaagacga agaattagat tgtgaagaca aagaattgga
     2821 tgatgattat gatgagttaa cagacgaagg tgaaatggag gataatgaag atgaattagt
     2881 agaagataag aacacaggct atgaaaatat agaaaatgat gaagatatag tatatgatga
     2941 ggaactatac aacattaatg agcaagaatc cgaatacaat tataatgaaa aaaatactaa
     3001 aactagagct aagaaaaaac gataattaac taaatacata aagaaaaaag gaagaaaaag
     3061 taatgataga ataagattat ctcaattact atataaaacc actttaaaaa attcaaaatt
     3121 tattatataa taataatatg aaatcctgaa acatacgata aggctttttt aaattcaacc
     3181 tacaaatgaa atacgggaga ccgtgtctgg taaattataa catgcctagt tagtttggac
     3241 gttaaaggtt actggcaagt cacccacctg ggagtgccta gggtgtgaat ttacttagcc
     3301 accggtgttt cgggacaaaa aaagtgctac tatttcaaat agtagtactt tttttattaa
     3361 tatgcatttt tctactaaat acgcctaatt attgataaat tcaaaaagca agtaacaatt
     3421 aagattataa aagcatagta ttaattaggc ttcaaaaagc caaagactta ataagaatcg
     3481 cttacaggga gggcaatgaa aaatgcaaga ttataaaaaa aataaaagaa gaatgatgaa
     3541 tcagccaatg tctacaatga atgaagaaga agtgtataca gatgaaataa attcagaaga
     3601 catgagaggt tttaaaaaat cacaccatca taatggatgt aatactgata ataagtgtga
     3661 gtgccatgat gattgcaatc catgcaaccc atgtaatcca tgtaaaccta acccatgcaa
     3721 tccatgcaaa cctaatccat gtgatgacaa ttgtggatgc catgacaatt gtaaatgtga
     3781 ttgtgaacca tgtgaaatgg attcagatga atgttttgaa aacaaatgtg gaccagaatg
     3841 ctgtaatcct atatctccaa gaaacttctc tgtatcaaat gcagtgccat ttgcaataga
     3901 ggctaataga atatttgata ctatgcaatt ccaaacattt acagatgcaa caggaccaaa
     3961 tggagagcca ttaacttttg aaacagaagt agtagaagta tttggttcag ttccaagtgc
     4021 aggtcaagca agtgtaacta tagaaaaaat atgcttaagt aatgatggaa tcgttataga
     4081 cacaggaatg acaactttag aagatttcga tttagaccca ttaggagata tagtaggaag
     4141 aaactgtgaa acaacttttg aatttgcagt ttgtggagaa agaaacgctg agtgctgtag
     4201 acaaggaaaa ggcaaatcag tagcttataa acaaagagga ttaactgtag cagttcgtaa
     4261 tttagtacta gagctaagag gtagatgtgg atgtacagag ttcgttgcat tagctttccc
     4321 agcagttaga gcaggaggtg gatgtaagag aagagttgat tatgtagaat ttacttttaa
     4381 cacactttca gcaccaatat gcttgccagc tgacggaaga gctgttactt taagacaaga
     4441 atatcaaact aacttaactg tagattgtat aggaaaatct atattaaaat tagaatgcaa
     4501 cgaatgttgt gaacctttct atgaattaat tataccaaat gatatagatt tagtactttg
     4561 cttacaagaa acagttagca cattaataag tgaacaaata gtagttttag catcaccaaa
     4621 tccaatccaa ccaagacttg ttgatacttt ctctaaagta tgtgattttt cgcaatgtgg
     4681 acctaatcat ggaagtggaa agccaagttg ccacagatag ataggtaaga tatatagaca
     4741 gtttaaatta taaataaaaa tcatctaagg aaggctacca aagtgtataa tttacattgg
     4801 tagccttcac gtttttataa ctagcgtata gattttagtg atttaaaaag cactatagta
     4861 tgtaatagac aagtaaagat tgatactatc gtcattgtgt atatgtatgc ataaatatta
     4921 agtcctggaa ttggaagaaa tacatataaa gctattagtt gaattaacat gccagtaata
     4981 gtatttatac ttgaagctaa ttcttttctt attgaatgta aaatgccaga tagagtttga
     5041 tttagggaca taaatagtgg aactaaaaac atagctttta gatattctcc tgcaagtgta
     5101 tttttaaata ctaatataca taaatctttt ccaaagaaat aaaaaaatat tgatgatagt
     5161 atgcctacaa ataaagtaag aagtatggag tatttgattt ttttaattac actcttacgc
     5221 tttcttagag ccatttcttg tgaaatagtt ggtattaaat ttacaataag cgctgaacca
     5281 acagtaaaag gtaaaaatat aaaaggcatt accatcccac tgacaatacc atacatactt
     5341 aaagattgtt gataagtcat tcctgataat gctaatcttg atggtatcat catagaactt
     5401 atagattgca aaagtatgtt tgacattcta ttacaagtta tgggaataga catttttaat
     5461 gtttccatag aagaattata aaaatctttt atgcttataa tatacctatt gtcaaatgat
     5521 gaatctcgcc ataagcaaat aagcataaat ataatattac tcaactcacc gattgatata
     5581 cctaatagag ctatataaca attcatagat ttattattta tgtacataac tagtaaaaaa
     5641 acaaataata ttttaccaat ttgttcaatg atttgtccaa tagcagggat ttttacattc
     5701 tttatgccat agtaatatcc tcttagtacg tttgaaagag ttattataac tatagcagga
     5761 caaacagcta gtataaatag atttaattta gcatctttta aaaatttaag tgataaaaaa
     5821 gaactattga aagatgcaac tatagatata attagtgcta cgaaaaatga tatatataaa
     5881 gttgatataa ataaagcatt agtattgtgt ctatcgttta aagcttttct ctttgcaact
     5941 agacaactaa gtgcagtagg tatacctgtt gttgtaacag ctaagcaaat catcaaaaag
     6001 ttaaaaatca tatgatagat acctaaacct gtttcaccta gtgctcttga taagaatatt
     6061 ttatataaaa aaccaaatat tcttacaata aaattggata taaataaaat aactgttgat
     6121 agtactaaat aaggtacttt caaaaaaatc acctccttat cttttaaata tattcacaag
     6181 gaggtgtaaa aatttataat tttataaatt ctggtttcaa tttattaaat ttagatacat
     6241 atttaaatcc catatttttt agtaatgaat atatgtagtc aaactcacat gcaacttgac
     6301 ttatatgatg tgaatctgaa cctgtggtta tgatttcccc tcccaagtct ttatacattt
     6361 gaagtatata cttagatggg gttaggtctg gaagattata tctataacaa gaggtattta
     6421 tctcgatacc tttgccatca taaatagctt gtttaagagt ttcttcaatt atatcagaaa
     6481 atagtctatc atctaaaata gtgtcataag gtgcatacct tttaatcaaa tctaaatgac
     6541 ctaagacaga gtaatcttta taattcttaa caatattata taaataaaga tagtaatttt
     6601 cataaacttc atgttgagtt ttatctttaa aataattacc aaggtataag tccattgtat
     6661 ctatagcatg gatagaacat attataaagt ccaatggata ttgatgtgct tcctttttgt
     6721 atgtatccat taattgagtt tgaactccaa attcaattcc tttttttatt gatattttat
     6781 ctttatattt gctttgaaga gtctctaaac tcttaaaata atcttcgtag acaattgaaa
     6841 aagaatcatc agcatataca tcatagtcaa catggtctgt gaaacaaatt tcctccaaac
     6901 cgagttcaat agattttttt accatttctt ccattgtaga ttttccgtct gtagagaaac
     6961 ttgagtgcat gtgatagtcg taaaacataa atatttcccc tttttataaa aattttggta
     7021 ttatatatac atactaaata atatcaaata tacataaaag catcaataaa atataaatac
     7081 aatgagcggt gataaatttg gaaaaataca gaatagattt aaatgagaaa aaatcaacta
     7141 aatatataca gatatttaat catataaaag aattgataat aaataaagag ttagtagaac
     7201 atgaaaaatt gcctccaata agaaaactat caaatttttt acaagtaaat aacactacta
     7261 tagttaaggt atacgagctt ttagaaaatg aaggatatgt atataaaatt atagggagtg
     7321 gtacttttgt atcaagttta aattcttata aaagcggtat agataacagg aaaaataaga
     7381 ttattgtgca aagagaagat ttaattcatt ttgacaatgg gaatccatct aatgatatgt
     7441 ttcctatcga ttcatttaaa aatgctgtaa atatggcatt atctaaagat ggtagttcaa
     7501 tatttgaata tgatgaaggt cttggctctg aagaattaag agaaaaaatg gtagagtatc
     7561 taagtgatgg aaatataaaa actactaagg aaaatattca aataatatca ggtgctcaac
     7621 aaggtataga tatagtttgt aaaggactta taagttattc agatgttgtt tttatggaag
     7681 aaccttctta caatggagca attgaagtgt ttaaaagtag aggtgcaaaa ataatatcta
     7741 tacctatgtt agatgatgga attgatatag gtattttaaa attaaagttg gaaaaaataa
     7801 aaccaagact tatatacatt atgcctaatt ttcaaaatcc aactggaata tcttactcaa
     7861 catataaaaa aaagaaattg atagaattgg cagaagaaca tgatttttat ataatagaag
     7921 atgattttat aagtgatttt gtttttgaat caaaggacaa tagaacaatt agaagttatg
     7981 atgataaaaa tagagtagta tatataaaaa gcttttcaaa aatacttatg ccaggtctta
     8041 ggataggaat tgtagaaatg ccaaatgagt tgttaaaaaa agttttatgg gctaaatatt
     8101 catcagatat atcaacacca ggtttaattc aaaaatcaat gtattactat atgaataatt
     8161 ttgattggaa gaattatttg agtcatatag aaaagatata tactgataag tataaattgg
     8221 caaaaaactt gattaatgac aaattgagtg gtaaattaaa agttagaaaa tcttgtggag
     8281 gaataaactt ttttttagaa ttaccaagag gatatacatc tcaagcattt acaaatttta
     8341 tgttaaacaa aggagtgtca atgcttccag ggacttattt ttttgacaat ctagtggatg
     8401 atagattctt taggataaat atagctcgcc caagcatgga agaactagaa aagggaatat
     8461 ctataataag tgataatata gatgagtttt tttgtgaata taaaaacaag ttagatataa
     8521 aaagcaataa attattttat taaataaata gaggtttttt aggaggaaaa aatgtttgac
     8581 aagaagaaat tagataggat taatgaatta gcaaagaaaa ataaagaggg aatcctttct
     8641 gctgatgaaa tcaaagaaag agaaatttta aggaaagaat atttagaaaa ctttagagcc
     8701 cactttagat caagactaga tagtgtcaaa gtagtttcac cagaagaata tgagcaatac
     8761 atgaaaaaca ataaaaatta gaacttagta ggaggaaaat atgaacttaa agtacgaatt
     8821 taagaatgct tgggattttg aaagaaaaga aaatactatt gaacaaatta tgcaatattc
     8881 tagcaattat atggagtttt taagtaagtc aaagactgaa agactttcag taaaagaaat
     8941 tataaaattg gctaaagaaa ataactatat ttcaatagat gaagctatgg aaaaaggaag
     9001 cataagttgt ggtgataaga tttatgttat aaataaagag aaggcagtag cactttttgt
     9061 aataggtaaa aattatatag aaaaaggtat gaagattata ggaagccata tagattcgcc
     9121 aagattagat ttaaaaccaa atccactgta tcaagagagt aatctaggtt tttttaagac
     9181 tcattattat ggtggaataa aaaaatacca atggacggct attccacttg ctttacatgg
     9241 tatagttata ttaaatgatg gaacaaaagt ggacatatct attggggaag aagatagtga
     9301 cccagtattt tgtgtaactg atttattgat tcatttggct ggagaccaaa tgcaaaagaa
     9361 actatcagaa ggaattagtg gagaagcttt aaatatatta attggaaata tgcctttaga
     9421 agatgaagaa aaagaaccta taacagcaaa tatattaaag attttaaatg agaaatacaa
     9481 tatagttgaa gaagatttat taagtgctga aattgaagta gttccagctg gtaaggctag
     9541 agatttaggg cttgataggt ctatggtgtt gggatatggg catgatgata gggtatgttc
     9601 atatgctgct gtaaaagcta tactagaaac tgaacaacca gaatttactt cagttgcatt
     9661 atgtgtagat aaagaagaaa ttggttctaa agggaataca ggtatgcact caaagttttt
     9721 tgaaaatact gtggctgaac tgattgcttt agaaggagat tattgtgata ttaaagtaag
     9781 aagagcttta gcaaatagta aggtattatc agctgatgtt tctgctggat atgacccaaa
     9841 ttttggagaa gcatatgaaa agagaaattc ggcatatatg ggaaatggag tagttttaac
     9901 taagtataca ggttcaagag gaaagagtgg atgtaatgat gctaatgctg aatttatgtc
     9961 agaagtaaag agaattttta ataaaggaaa tgtaatatgg caaactgctg aacttggaaa
    10021 agtagaccaa ggaggaggcg gaactatagc ccatatattg gcaaatcaag gtgcagaggt
    10081 tatagactgt ggtgttggag ttttaaatat gcatgcacca catgagattg tctctaaagt
    10141 agacatatat gaaatgtata agggatataa ggcatttttt aatataaatt tataagtaaa
    10201 aatataaatg taataagtga ataaaggctg ttgtataaac aatttaatct gttgtacaac
    10261 agtcttattt ttatgtaaaa atagcaattt gtcacactag agaaaataaa agaaaatact
    10321 gtcaaattaa aaattattta aaaaaaaatt gacaacgatt tcatcttgtt ataatatgta
    10381 ataaagaact tgttatataa tgttataaaa atgttacata gggaggtgag caaaatggat
    10441 gaaaagagac aaaaaaaaga aatggattta gaagtaaatt cctttgttcc tttatatcaa
    10501 caactatatg acaacataaa aaaacaaata gcatctggca tatataaacc aggagataaa
    10561 cttccatctg aaggagactt atgtaaagaa tttaatataa gtcgtataac tgtgagaaat
    10621 gcacttaatg aacttgtaaa agaagatata ttatgtaaaa aacgtggtaa agggacttat
    10681 gtaacaatac cagagagaat agaagcaaca tgtgcaggaa atagttttac taattcttgt
    10741 catcgtatta atgcaaaacc aagtaccaaa ataatctctg ttttaataaa aaaagcagat
    10801 aagcaagtag ctgaagcttt aagtattgaa ctagaagaga aggtaatatg tattaaaaga
    10861 cttagattaa tagatgaagt acctgttatt tttgaagttg actattttag aatagattac
    10921 atgtttttat taaaagaaga attagaagat aaatctttaa tggaggttat atctaataat
    10981 ataagcacat tacctaaacg agtagaaaat atatttgaag taaaacattc aaacaaagaa
    11041 tattctgacc atcttaaatg tgcaagtaat atgccactat tgaaagtaag acaatcggtg
    11101 tatacagaaa ataatgatgt cttatattac aatgagcaat ttataagaag tgataagtac
    11161 aaatatgcag tatcagcaga aatataatct ataatttagt aggaggatga gtatgaaaaa
    11221 gataatatta gcatctcatg gagacttttc aaaagggctt ttaaatgcag taaaaatgat
    11281 agtaggagat ttagcagatt gtgtcagttc gtatggtttg taccctggac aaagtgcttc
    11341 agattttgct ttagaattag aaaaaacaat atcagaagat aaagaatgtg aatatataat
    11401 tttatctgac ttatatggag caagtgtatg tacagcaatg ttaagattaa ctaatctaca
    11461 taatgttagg ttattttctg gaatgaattt gaatatggta ttagaacttc ttacaaggtt
    11521 ttctgatgaa ttaacagttg aagatataga ccaattagtg gaagaatcta gaagaggaat
    11581 acaaagcgtg acattacaaa ttaaagaaga agaagaggta ttttagttta tgaaaaaaaa
    11641 gggaatatta tcagtattta aaagtaaaaa accaattata gcaatgatac acttaaaagg
    11701 agatactcca gaagatatct ttgaaagagc taaaaaagag attacaatct ttgaagaaaa
    11761 tggtgtagat ggaataatgt tagaaaatta ctatggtaat tattatgatt tagaaagaat
    11821 acttgaatat gtatcaaaag ctaatttatc aataccatat ggagtaaact gtttaaatgt
    11881 tgatactatg ggatttgaac tggcaacaaa atataatgct agttatatac aggttgattc
    11941 tgtagtaggt catgttaaac ctagagatga agctacttta gaagagtttt ttaaattaca
    12001 acgttcaaaa tgtccagcgt atttaattgg aggcgtacgt tttaaatatc agccagtatt
    12061 atcagaaaat gatgttgaag aagatttaaa aataggaatg acaagatgtg atgctatagc
    12121 agttacagaa aatgctacag gtcaagaaac atcaatggaa aaaatagaac tgtttcgtaa
    12181 aaatttagga gacttcccat tggttatagc tgctggagtt acattagaaa atgcaaaaaa
    12241 acagcttaaa ttaggagata tggcaataat aggaagttac tttaaagata attacaaaga
    12301 ttttggggat gttagtgtag aacacgtaaa aacattcatg gatgaaatca aaaaaattag
    12361 ggaggaatta taatgattaa attagtaaga gtagaccaca gacttataca tggacaagta
    12421 gcatttacat ggacaaagtt tttaagtaca gactgtatat tgatagcaag tgatgactta
    12481 ttaaaagatg aattaagaat ggcaggactt aaaatggcta aaccatctaa tgttaagtta
    12541 gtaatgaaaa gcatagcaga ttctataaaa gcacttaact caggtgttac tgataaatac
    12601 aacttattga tactttgtga atctgtagaa gatgtttaca gacttgctaa agaggtaaaa
    12661 gctattaaat ctataaacct tggtggaaca aaatcagatg ataatcgtga aaatatatct
    12721 aaagcagtgc atgtatcaaa agatgatata aagatgatta aagagttaga ttcagaaggc
    12781 gtaaatgtat ttgtacaatt agttcctgat gatgatgcta caaatgtaat gaaattaata
    12841 taattttagg gggatgaaaa tggaatttac acaagttatt ttgataactc taattgcatt
    12901 ctttgcatat atgcatagtt ttgtaggttc tacaatgcat aatagaccta tagttgttgc
    12961 accacttgtt ggtttagcac taggtaatct tcatacaggt atagtaatag gttcaacatt
    13021 agaattagta tttatgggtg catttcctgt tggggcaagt aatcctcctg attttgtgtc
    13081 tggttctatt attgccacag cgtttgtaat attaacgggt caagatgtat cagcagcagt
    13141 tgtacttgca gttcctatag caactctagt attgcttata gataacttct taatgacagt
    13201 agtacttaca tggggagctc atattgctga ccgttatgca gaagagggga atattgaagg
    13261 cgtagaacgt gtgcaattat tatttggtat aggaaataaa ttaatattag caataatagt
    13321 aggtatagga ttttcattag gtgttccagt aatagaaaaa atactttcat ttataccatc
    13381 atatgtaact catggaatgg atgttgcagc aggcgtgatt ccagcaatag gttttgccat
    13441 gttagctaga atgatgctta ataagaaaac agtagcattt ttattattag gatttatatt
    13501 ggttgcttac ctaaacataa cagtaacagg agttgcattg tttggattag caatagcttt
    13561 aatatatgtt aactttgtag gagagaagga ggtaatagta gatgacaacg agttctaaga
    13621 aattagagac aatttcacca gatagtaaaa taacgaggaa agacttttgg aaatgtttta
    13681 gaaggtcatt gacattagat tcatcttgga actacgaacg tatgcaaaat atagcatatg
    13741 catacatgat ggcaccaata atccgtagat tatataaaga tgataaagaa aagaaatcta
    13801 aggctttaaa aagacattta gaatttatgt cagttactcc tcatataagt actcttttgg
    13861 taggtatatc tggagctatg gaagaagaaa atgcaaagaa taaagaattt gatgctaata
    13921 gtataaatgc tgttaaatca agtttaatgg gtccagtttc tgggatagga gattcatttt
    13981 tctggggaac attaaagctt atagcagctg gggttggtat agctttagct tctcagggta
    14041 acataatggg accgatttta ttccttttaa taataaatgt tcctcatttt attatacgct
    14101 atatatgtct agataaagga tttaagtatg gaactcaatt ctttaaagat gtgagtggtt
    14161 caagtatagt ttcaaaagtt atggaagcag cttcaatgtt agggcttatg gtaattggag
    14221 gtatgactgc atctaatgta atgttaaaac ttagtgttaa tgtaggtagt ggagaatggg
    14281 cagagcctat tcaaacttac ttagaccaaa taatgccatg tatgcttcca gctatgatat
    14341 tcggtattat gtattggtta ttaggaaaaa aggtaaagac aactacgata ttaatttcag
    14401 ttatgattat ttgtatagta ttggctgcta ttggagtagt ataaataaaa aaatcccaag
    14461 ttcatttgaa cgagggattt tttgactaaa ttaaataaaa aagaaagatg gttcataata
    14521 atttataagc atttatgtga tagttataat tagcttatta attagttata aactcaaaat
    14581 taagcactac tttattaaag ttattatatt ataatttcga aatactcaca taatctgttt
    14641 agaaatttat cttctaatgg ggaaaaagtt ttctttttag agtaaatgaa gaaaaacttt
    14701 ctagtaaaat caacatcctt tattttataa cattttattt tacctgcatt gagataatcg
    14761 atagctgaaa tgtacgatat aaaggacact ccaagaccta atctaaccat ttccttaata
    14821 gcctcatttg attctacatg agcgattaca tttaatttac ttactggaaa gttattttta
    14881 ctaagtgtgt ttagtattaa gtttcttgta cctgaccctt cttttctcat aataaaattt
    14941 agataagcca attctcctat atcgatacaa ttatttttat tatcaatttt aaaatctgaa
    15001 ggagtgataa gaacaagttc atcatctaat aagtctaggt actctatttg aggattattg
    15061 attttagaac caactaatcc aaagcttatt cgttcattta aaatttctga tatagcatat
    15121 tgagaatcat aatggcttat ggaaaatttt acatctggat aactcataga aaaactcttc
    15181 ataaaatcag gtaaaatata agtttcaggt atggaactac atgctatatc tataatacct
    15241 tctatttttc ctgaatattc ttttatatca taaattgcac gtttgcaatt attcaatata
    15301 tatatagcat gttcataaag aatttcacca gattttgtga gtgtaataac tttgttgctt
    15361 ctatttataa gaacagtttc tagctctctc tctaaattct gtatgtgtgc gcttacagta
    15421 ggttgagtta aaaaaagttc tcttgcagcc tttgaaaaac tctgatgttt tgcaacagca
    15481 acaaatactt caagttgttt aaaatccatt atttaatcct ccttaaatta tctaaaacta
    15541 ttataacata tttgataaat taatagtcaa aggtgatttt taaaatagaa aacctttaaa
    15601 tattcatgga gtttttgatt gtttaggaat aatttggtat aatgttgtaa ggtacttaca
    15661 ataaaaatat cgtaaattga attttcaaaa ttcaacttta aagtgttttt tattacagaa
    15721 aaattacaat ta
//
LOCUS       DAYAOO010000095        15221 bp    DNA     linear   BCT 12-OCT-2024
DEFINITION  TPA_asm: Clostridioides difficile isolate ST8-SSI-h139-18
            SAMN40601845-rid21577343.denovo.096, whole genome shotgun sequence.
ACCESSION   DAYAOO010000095 DAYAOO010000000
VERSION     DAYAOO010000095.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN40601845
            Sequence Read Archive: SRR28438827
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 15221)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 15221)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-MAY-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-MAY-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002157583.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002157583.1
            Genome Coverage       :: 163x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/11/2024 16:19:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 4,038
            CDSs (total)                      :: 3,963
            Genes (coding)                    :: 3,930
            CDSs (with protein)               :: 3,930
            Genes (RNA)                       :: 75
            rRNAs                             :: 6, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 60
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 33
            CDSs (without protein)            :: 33
            Pseudo Genes (ambiguous residues) :: 0 of 33
            Pseudo Genes (frameshifted)       :: 7 of 33
            Pseudo Genes (incomplete)         :: 25 of 33
            Pseudo Genes (internal stop)      :: 11 of 33
            Pseudo Genes (multiple problems)  :: 8 of 33
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..15221
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN40601845-rid21577343.denovo.096"
                     /isolate="ST8-SSI-h139-18"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Denmark"
                     /collection_date="2018"
                     /collected_by="Statens Serum Institute"
     gene            332..913
                     /locus_tag="ACGI5H_003235"
     CDS             332..913
                     /locus_tag="ACGI5H_003235"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000146723.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0006950 - response to stress [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TerD family protein"
                     /protein_id="HFG9698925.1"
                     /translation="MMGITLSKGQKVDLTKGNPGLKNILVGLGWDTNKYDGGFDFDLD
                     TAAFLTGASGSVTNDGDFVFYNNLKHTSGAVEHLGDNRTGEGDGDDEQIVVDLSKIPG
                     EISKISFTVTIHDATERRQNFGQVSNSYIRIVDKDTNEELIKYELGEDFSIETAIVVA
                     EIYKHNGEWKFNALGSGFEGGLAALCGNFGINL"
     gene            952..1530
                     /locus_tag="ACGI5H_003236"
     CDS             952..1530
                     /locus_tag="ACGI5H_003236"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889542.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0006950 - response to stress [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TerD family protein"
                     /protein_id="HFG9698926.1"
                     /translation="MAIVLKKGQKIDLTKGNPGLKNIKLGLGWDTNSFDSGYDYDLDV
                     SVFMVGESQRVEKDEDFIFYNNLKHPSGAVEHLGDNRTGEGDGDDEEILVNLETMPKH
                     IQKIAVTVTIYEAAERRQNFGQVSNSYIRVLNSENDEEILRYDLGEEFSIETAITVCE
                     IYKYNGEWKFSAVGAGFEGGLEALCRNYGLNV"
     gene            1616..2245
                     /locus_tag="ACGI5H_003237"
     CDS             1616..2245
                     /locus_tag="ACGI5H_003237"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728871.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0006950 - response to stress [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TerD family protein"
                     /protein_id="HFG9698927.1"
                     /translation="MSINLSKGDKIDLKKSNPGLSNILVGLGWDPVQQSGGGFFKSLF
                     GGGQADIDCDASVFMLNQEGKLSGIKDLIYFGNLKSACKSVLHTGDNLTGEGTGDDEQ
                     ILVNLDKVPSNIHKLLFVVNIYNCVDRKQHFGMIENAYIRVEDQGNKKEIAKYNLSDN
                     YSEKTTLIVGAIYRKDGSWQFKAIGEGTKDAGLKEVMQNLDRIECAYGI"
     gene            2235..4994
                     /locus_tag="ACGI5H_003238"
     CDS             2235..4994
                     /locus_tag="ACGI5H_003238"
                     /EC_number="7.2.2.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420276.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0005388 - P-type calcium transporter
                     activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006816 - calcium ion transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="calcium-translocating P-type ATPase, PMCA-type"
                     /protein_id="HFG9698928.1"
                     /translation="MEFNNDIKYYNVDKEEVTKDLSVNPEKGLSESEVKTRREKYGLN
                     EFTPKEEGSFWDDLKESLSEPMIVILIIAAVVSAVIGETHDAIGIVGAIAIGIAIGMI
                     TEGRSKKAAEALSKLTENIEVKVLRDGEVHQISKSELVPGDIVYIETGDMVPADGRLI
                     ESINLKIREDMLTGESDDVSKKCDVVVSMEEIESKGAVVVQEPIPAKQINMVFGGTLV
                     AYGRGALVVTSIGDNSEMGKIAQNLSETDEQTPLQIKLGNLGGLIAKVSSAVAGLLFI
                     FMVFQMISKNVLNVDMSGILPFLESIDPVKTAFTVCVALIVAAVPEGLPTMINMTLAI
                     TMQKMAKINALVTKKEACETIGSVSVICSDKTGTLTENRMTVEVAYVDGRYIESSEEE
                     INSYFEENCMINSTADVEHNDGDIKYLGSATECALLLYYKNVDYRQVRKNSNIVAQNP
                     FTSDSKRMTSVIGQDNHHVLLSKGAPEVLLELCSHIQRGKDIVPLTENIKHEILEEIK
                     KLQIKSMRTLGFAYKEISQAEEEAAVTAESDAMNVSAMENNLVFSGFVGIRDPLRKDV
                     IESVNTANKAGVSVKMLTGDNINTARAIGEELGLLKNNMRVVEASYIDTLDDEELKQE
                     IQSISIVARSKPDSKMRIVSALQKSGDVVAVTGDGINDAPALSKADVGIAMGISGTEV
                     SKNAADIILTDDSFSTIVKGIKWGRGIYDNFQRFVQFQLTVNVIAFLVAIISQVMGQE
                     MPFTTIQLLWVNIIMDGPPALALGLEPVRDHVLNRKPVDRKANIISKSMVYTIVLNAF
                     YITAILMLQSTFNFLGVDEAHKGTVMFALFAFSALFNAFNCREFNADSIFPNFTHNKL
                     ALQIIVLTGIAQVIFTQLFQDFFNSVAMDFMTWVKVLCVAASVIVVNEVVKCIIRLVK
                     LKKTA"
     gene            5081..6643
                     /locus_tag="ACGI5H_003239"
     CDS             5081..6643
                     /locus_tag="ACGI5H_003239"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430080.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YceG family protein"
                     /protein_id="HFG9698929.1"
                     /translation="MGDSKVFEKIFSSQSDRGNYTPSKGYLSYFISYIGLEDEVLYNL
                     EIFKTKQNIDSKKDIALFTDVIANPSDFDIINYFKSGLQKYRTSMEDVDINILGFEEI
                     DYKIKQAMDRVLKEEEKEFTNDRVKQNFIVKIMAWIKIYIGALDINKNEAPKVIFYGD
                     IKKHEVYLLLILYLAGFDVLYLNPNSKSNIDILKSERYNIEFEEANIIEEKISFEERV
                     ILGEKIDKSSVKKAFTVGAEASKRISEELLNDAGFIKPWQLQDRKIKNLLLSSTVDEI
                     SIYWNQPLKLRPGFKFNDAIVEAPNFLSKINGIYNDKNEYIKFLDLLRDSESSTFIEF
                     NGDVDRFSKAFTREAFSLSFLLDSKGAIDKNSVLNNKDYSISTLALNQQIMILEKVEE
                     LLEGSMFLNGLSGEDKIKGLFTVLHMDKKFVHMMNNFDYSLINPKLIIYMYKSIVFDK
                     EIVFLMLLLSKIGFDIIILCPGGENNIENVINNQLIDVHRLDKMVYDLKLNSLENDIP
                     LLKKIFGKRRRF"
     gene            6644..7780
                     /locus_tag="ACGI5H_003240"
     CDS             6644..7780
                     /locus_tag="ACGI5H_003240"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430084.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="toxic anion resistance protein"
                     /protein_id="HFG9698930.1"
                     /translation="MGININSFSKDKNSVEVTENLPTAVQEENFDIMEYTNNKKNELR
                     KSKEVEALTSLIEVENPDTILQFGRKASEGVARVSDSLLNTIKLNRNEENSKMLVHLT
                     KIMDKFDLDDFQETKEPNFVQKLFKKANNAIEMMFQKYETLGGEVEKIQIELEQYERD
                     IALSNKQIGAMLNENFEFYNELQKYIVAGEMAIEEMDNEILPFFKQKSETSGDQMDVV
                     NYQELLKVYDMLNQRVYDLRIAENIAIQTIPMLRGMQHNNYGLIRKINSAFVVTLPVF
                     KQCLSQAILLKKQELQAKSLKALDDKTNELLLRNAQNVSTQSAQIARMAGTSSVQIET
                     LEKMYNTIKSGIDETMRIEENNRALIKDNTKRLEELNTTIIYNK"
     gene            7844..8920
                     /locus_tag="ACGI5H_003241"
     CDS             7844..8920
                     /locus_tag="ACGI5H_003241"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433662.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HpcH/HpaI aldolase/citrate lyase family protein"
                     /protein_id="HFG9698931.1"
                     /translation="MKYFDYICKDDLERIFLKEPEDFSAKTEKDVLKYALGAFLYVPA
                     TQYNMIYKSIIGDVKGVRPLAICLEDAVGVNGELEAIENLRLILKNISNESITNKDGI
                     PLIFVRIKDVEQLLRIKEIIIKNSHFITGILIPKANSELIENCIEALDFMNLQDMYVI
                     PIVETKEFIYNEKKELSFTNLYNAILRHKSRILSIRVGITDILGMYGIRRDKNFSIYN
                     NLICSSFILDIITYLQRPELDIPISGGVSEFFDMTNKDIRNKYIEEILLDKYHGLIGK
                     TVIHPMQIQIVQALSTVSYEDFTDALDILDSTDSKYGVSKGVLGERMNETNPHFLWAK
                     KTLILSKIYGVLNKGVDYEELLKF"
     gene            8898..10136
                     /locus_tag="ACGI5H_003242"
     CDS             8898..10136
                     /locus_tag="ACGI5H_003242"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420284.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosyltransferase family protein"
                     /protein_id="HFG9698932.1"
                     /translation="MKNCLNFNCEIDIIDNPLNLELNDFLDVGIRNNSKRRFLFISKK
                     LGKHLACKPSEMDNLGKLMATIYNEKNKEESNGTVIAFAETGTAVGHSFFDYLCGDYE
                     FIHTTREQFDELENLEFLEEHSHATDQNLYFGMLNNFKFGDEIILVDDEITTANTCMN
                     IIRKIQSIYPKKKYTICSILNWVSDENLSKVTRLERELDCKIDFVYLFKGNFKFYIDE
                     DIISNYNDNYSITKLETISSDKVNLVVNHIYVDLEDYIGNKKYVKYTGRFGINRREQF
                     RLKEIVKRESKKITMASKESLKNEKEKILFLGTEEFMYIPMLFAKEKENQYDIYYHST
                     TRSPIINIDKNNYPIKSKFMLKSFYNIDIQNYIYNIDKHNFSKCYLFVELNKSENSYL
                     EFIDIIKKTSIKELTIVCCS"
     gene            10190..11278
                     /locus_tag="ACGI5H_003243"
     CDS             10190..11278
                     /locus_tag="ACGI5H_003243"
                     /EC_number="3.4.22.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902680.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine protease StiP family protein"
                     /protein_id="HFG9698933.1"
                     /translation="MRDFSTYSKDDVIFLLKDISNLIEEEGNKERELKIQNGRHYSEM
                     IPIEYEVSEDYLNLYHEKLRENKDKLAFSIGVMCEKIIKKNGNDVVLVSLARAGTPIG
                     ILAKRYIRSKYNISLPHYTISIIRDKGIDMNAIEYIVKNHPSSKIQFLDGWTGKGTIS
                     KELEKACDELNVKFKKYFDSTLAVLADPAGYSGLYGIREDFLIPSACLNSTVSGLVSR
                     TVLREDLIGKNDFHGAKFYRHLKDKDESMNYIETIEECFKNQFKNISDEVENWESDII
                     TRDGYFDVLNIKEKYNITDINFIKPGVGETTRVLLRRVPYKILVKDLNDKSLDHIFIL
                     AKEKNVEVEQMDLKAYKCCGIIKNMKDI"
     gene            11306..12097
                     /locus_tag="ACGI5H_003244"
     CDS             11306..12097
                     /locus_tag="ACGI5H_003244"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889544.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD hydrolase family protein"
                     /protein_id="HFG9698934.1"
                     /translation="MIVFSDLDRSIIYSNKFLNADSKYTNIEIYREKEISYISLDTIN
                     LIKQIQYYGMFIPTTTRTVEQFKRIEFNKYGIYFPWSITSNGGVILKDNEILKSWSEK
                     IDKLKCDYEPIESMIHKFKDYLNVDGITNFKVAEDTFFYIVVDLSRFNLDSIKEYTNI
                     LESKNWKFYVSGRKIYFIPKEISKENAIKYLTKELGIEYFYAVGDSIMDYGMLNISNK
                     SYVLKHGDINKNEIENSFISSSFNGMSGTEEILSNILDENCLLNI"
     gene            complement(12212..12766)
                     /locus_tag="ACGI5H_003245"
     CDS             complement(12212..12766)
                     /locus_tag="ACGI5H_003245"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420290.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cupin domain-containing protein"
                     /protein_id="HFG9698935.1"
                     /translation="MNIDVGSKIRSLRKSKNISISTLAKNSDLSTGLISQIERNMVVP
                     SIVAMWKISKALDINIGYFFEEIGREDSDIVVKKNNRKKIVTNDSTKFYELLVPNLSG
                     KKIEFILVTLDGHTQKNSEFVTHEGEECGYIIKGKMKITLGNKEYLLEEGDSFYFNST
                     IPHVYENYDDEVCISVWAMTPPSF"
     gene            12962..14164
                     /locus_tag="ACGI5H_003246"
     CDS             12962..14164
                     /locus_tag="ACGI5H_003246"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905536.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF819 family protein"
                     /protein_id="HFG9698936.1"
                     /translation="MKSFVSPDNIWVLWAVVTGWAAFSIYLEQKYNWASKVSGAIIAL
                     VGAMLLSNLNIIPVESVVYDQVWGYVVPLAIALLLYQCNIKKIWKESGRLLIIFLVGS
                     VGTVLGAMIGFLALKNVVPDLNIVAAMMTGSYIGGNVNFAAMSGAFDAPGELVSATVV
                     ADNLLMALYFFVLIAIPSIGFFRKHFKHPHVDEMESIGITEGETVAANYWGRKEISLK
                     DIAIAIGSAFIIVAVSVELSTWFKAIIPLSNPFLAMLNTLFGNQYLIITTLTMLFATF
                     MPNFFGDIKGAQELGTFLIYIFFVVVGVPASITLIIQKSPLLLLYCGIMVLINMLVTF
                     IVAKIFKFSLEEAILASNANIGGPTTAAAMAISKGWSKLVGPILIVGTFGYIVGNYFG
                     LLVGNILI"
     gene            14221..15201
                     /locus_tag="ACGI5H_003247"
     CDS             14221..15201
                     /locus_tag="ACGI5H_003247"
                     /EC_number="3.4.13.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889546.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0070573 - metallodipeptidase activity
                     [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="membrane dipeptidase"
                     /protein_id="HFG9698937.1"
                     /translation="MIFDGHSDTWADVTIRRLNGEKDVFRRIHLDNFKRANIEGAIFV
                     IWIDPPYDKEPEKRVKQIISSIKDEIEDMKDVVNIVKKYSDIDKGISENKINILIGLE
                     GLSHIGRNIDLLDYFYKEVGARHASLTWNEQNELATGCLGDENRGLSEIGKKAVNKME
                     KLGMIVDVSHLNEKSFWDLMSVASKPVIASHSNARSLCDAKRNLTDNQLKEISNTGGL
                     VGINSFRGFTNSNPKKQDLIHLVDHIDYMVNLIGIEHVSFGFDFSDYLGKETIGSFTG
                     NASVPSVDGLESTHTAQNIVVELENRGYKKKDIELISSGNFYRLFKDILK"
BASE COUNT         5981 a         1579 c         2776 g         4885 t
ORIGIN      
        1 ggtagtagtg gcgaagacac cgtccgaagt agcttggctt tgtaaccacc tctgttgtac
       61 tgtttaagta taaataagtg tgttagccac caagaatccc cttgctttag ctatggggag
      121 tgtgtcaaat attaaacata gcttttatac atttaataag gtatgtaaaa tctatgtaaa
      181 aagtaagaaa tataaacatt tttttaatta tattttaaaa atatcaagca agttttcttc
      241 acaaatgaat aaaaaatgtt ataatatgat taaagaaaaa gataaataat tagcaagatt
      301 tgtttagcta aaattaacaa gggagcgata aattatgggt ataacattat caaaaggcca
      361 aaaggttgat ttaactaaag gaaatccagg tcttaaaaat attttagtag gtttaggatg
      421 ggatactaac aagtatgatg gtggatttga ctttgattta gatacagcag catttttaac
      481 aggagcaagt ggaagtgtta ctaatgatgg agattttgta ttttacaaca atttaaaaca
      541 tacatctgga gcagttgagc atctaggaga taacagaact ggcgaaggtg atggagatga
      601 tgaacaaata gttgttgatt tatctaagat tcctggagaa ataagcaaga tttcttttac
      661 tgttacaatt catgatgcaa cagaaagaag acaaaatttt ggacaagtaa gtaattctta
      721 tataagaata gtagataaag acacaaatga agagttaata aagtatgaat taggagaaga
      781 ttttagtata gaaacagcta tagtagtagc tgaaatatat aagcacaatg gagaatggaa
      841 gtttaatgca ctaggttctg gctttgaagg tggtcttgct gcattatgtg gaaactttgg
      901 aataaactta taatttcaac tataacaata aactaaaggg ggatattttc catggctata
      961 gtattaaaaa aaggacaaaa aatcgattta actaagggaa atccaggtct taaaaatata
     1021 aaacttggac taggatggga tacaaattca tttgatagtg gctatgatta tgatttagat
     1081 gtaagtgttt tcatggttgg agaatctcaa agagttgaaa aagatgaaga ttttatattc
     1141 tacaataact taaaacatcc atctggagca gttgaacact taggtgataa tagaactggt
     1201 gaaggtgatg gagatgatga ggaaatatta gtgaatttag agacaatgcc aaagcatata
     1261 caaaagatag ctgtaacagt tacaatatat gaggctgctg aaagaagaca aaattttgga
     1321 caagtaagta actcatatat aagagtatta aattctgaaa atgatgaaga aatattaaga
     1381 tatgacttag gtgaagaatt tagtatagaa actgcaatta cagtatgtga gatatataag
     1441 tataatggag aatggaagtt tagtgcagtt ggagcaggat ttgaaggtgg cttagaagca
     1501 ctttgtagaa actatggctt aaatgtttaa tttaagcaat ataatatatt aaatataaat
     1561 aacctataca aataatgtat aggttatatt atataaaatt ttgtggaggt ttagtatgtc
     1621 gattaattta tcaaaaggtg ataaaataga tttaaaaaaa tctaacccag gactgagtaa
     1681 catacttgta ggtctaggat gggaccctgt gcaacaatct ggtggaggtt tttttaaatc
     1741 gttatttggt ggaggacaag ctgatataga ttgtgatgca tctgtattta tgcttaatca
     1801 agaaggtaaa ttaagtggaa taaaagattt aatttatttt ggaaatctaa aaagtgcctg
     1861 taaatcagtt ttgcatacag gagacaatct aactggtgag ggtacaggtg atgatgaaca
     1921 aatcctagtt aatttggata aagttccatc aaatattcat aaattattgt ttgtagtaaa
     1981 tatatacaat tgtgtagata gaaaacaaca ctttggaatg atagaaaatg cctatataag
     2041 agttgaagac caaggtaata agaaagagat agcaaaatac aatctatctg ataattattc
     2101 tgaaaaaact actcttatag taggagctat atatagaaaa gatggaagtt ggcaatttaa
     2161 agcaattggt gaaggaacaa aagatgcggg tcttaaagaa gtaatgcaaa atttagacag
     2221 gattgagtgt gcatatggaa tttaataatg atatcaaata ttataatgta gataaagaag
     2281 aagttacaaa agacttatct gttaatcctg aaaaaggttt atcagaatca gaagtcaaga
     2341 ctagaagaga aaaatatggt ttgaatgaat ttactccaaa agaagagggt agtttttggg
     2401 atgatttaaa ggaaagttta agtgaaccaa tgatagttat cttgattatt gcagcagtag
     2461 taagtgcagt aattggggaa actcatgatg caatagggat tgtaggtgct atagcaatag
     2521 gtatagcaat aggtatgatt acagaaggtc gttctaagaa agcagcagag gctctttcta
     2581 agttgactga aaacatagaa gtaaaagtat tgagagatgg ggaagtacat caaatttcta
     2641 agagtgaatt ggtaccaggt gatatagtat atattgaaac tggtgacatg gtacctgctg
     2701 atggtagact tatagaaagt ataaacctta aaattagaga agatatgtta acaggagaat
     2761 ctgatgacgt atctaaaaag tgtgatgtag tagtttctat ggaagagata gaatctaaag
     2821 gagcagtagt agtacaggag ccaatacctg caaaacagat aaatatggtg tttggtggca
     2881 cacttgtagc ttatggtaga ggagctctag ttgtaacttc aattggagat aatagtgaaa
     2941 tgggtaaaat tgctcaaaac ttatcagaaa cagatgagca aactccactt cagataaaac
     3001 ttggaaattt aggtggtttg atagccaaag tttctagtgc agtagcagga ttactattta
     3061 tatttatggt tttccaaatg ataagtaaga atgtattaaa tgtagatatg tctggaatat
     3121 taccgttttt agaatcaata gacccagtta aaacagcatt tacagtatgt gttgcgttga
     3181 tagttgcagc agtgccagaa ggtcttccaa ctatgataaa tatgacactt gcaataacaa
     3241 tgcaaaaaat ggctaaaata aatgcattgg ttactaaaaa agaagcttgt gaaacgatag
     3301 gttctgtttc tgtaatatgt tcagataaaa ctggtacatt aactgaaaat agaatgactg
     3361 tagaagttgc atatgttgat ggcagatata ttgaaagttc agaagaggaa ataaatagtt
     3421 attttgaaga aaactgtatg ataaactcta cagctgatgt agagcacaat gatggtgata
     3481 ttaagtattt aggaagtgct actgaatgtg cattgctttt atattacaaa aacgtagatt
     3541 atagacaagt tagaaaaaat tctaatatag tagctcaaaa tccttttact tcagattcaa
     3601 agagaatgac ttctgttata ggtcaagata atcatcatgt actattatca aaaggagcac
     3661 cagaagtctt acttgaatta tgttcacata ttcaaagagg aaaagacata gttccattaa
     3721 ctgaaaatat aaaacatgag attttagaag aaataaagaa attgcaaata aaatcaatga
     3781 gaactttagg gtttgcatat aaagaaatct cacaagctga agaagaagca gcagtaactg
     3841 ctgaaagtga tgctatgaat gtaagtgcaa tggaaaacaa tttagtattt agtggttttg
     3901 ttggtataag agacccactt agaaaagatg ttatagagtc tgtaaataca gcaaataaag
     3961 ctggtgtttc tgtaaaaatg cttacaggag ataatataaa tacggcaaga gctataggtg
     4021 aagagttagg cctattaaaa aataatatga gagtggttga agcttcatat atagatactt
     4081 tagatgatga agaattaaaa caagagatac aaagtatttc aatcgtggca agaagtaaac
     4141 cagatagtaa aatgagaata gtttcagctc tgcaaaagag cggagatgtt gttgcagtaa
     4201 caggtgatgg tataaatgat gctccagcac tttcaaaagc agatgttggt atagcaatgg
     4261 gtatatctgg tacagaggta tctaaaaacg cagcagacat aattttaact gatgatagtt
     4321 ttagtaccat tgtaaaaggt attaaatggg gtagaggaat ttatgataac ttccaaagat
     4381 tcgttcaatt ccaattaact gtaaatgtaa ttgcattttt agtggctata atatctcaag
     4441 ttatgggaca agagatgcca tttactacaa tacaattatt atgggtaaac atcattatgg
     4501 atggaccacc agcactagca ttaggtttag agccagttag ggaccatgtg ttaaatagaa
     4561 aacctgttga tagaaaagcc aatataattt ctaagtcaat ggtgtataca atagtattaa
     4621 atgcatttta tataacagca atactaatgt tacaatctac atttaatttc ttaggagttg
     4681 atgaagcgca taagggaaca gtaatgtttg cgttatttgc ttttagtgca ctgtttaatg
     4741 catttaactg tagagagttt aatgcagata gtatcttccc taattttaca cataacaaat
     4801 tagcactaca aataatagtg ttgacaggaa ttgcacaagt aatatttact cagctattcc
     4861 aagatttctt taactctgta gcaatggatt ttatgacatg ggtaaaagtt ttatgtgtag
     4921 cagcaagtgt aattgtggtt aatgaagttg taaaatgtat aataagactg gtaaaactaa
     4981 aaaagactgc ttaaaacaaa ttttttagaa gaaaacagac tgactcaaaa tatgaatttt
     5041 gggtcagttc tgaataaaca tttaaattgg gaggatagtt atgggtgact caaaggtatt
     5101 tgaaaaaata ttctccagcc aatcagatag aggaaattac actccttcaa agggatatct
     5161 aagttatttt atttcgtata ttggtttaga agatgaagtt ttgtacaatc tcgagatatt
     5221 taagacaaaa caaaatattg atagcaaaaa agatattgct ttatttactg atgttatagc
     5281 aaatcctagt gattttgata ttataaatta ttttaaaagt ggacttcaaa aatatagaac
     5341 tagcatggaa gatgtagata taaatatttt gggatttgaa gagattgatt ataaaataaa
     5401 gcaagcaatg gatagagtgt taaaagaaga ggaaaaagaa tttactaatg atagagttaa
     5461 acaaaatttt atagtgaaaa taatggcatg gataaaaatt tatatcggtg ctttagatat
     5521 aaataaaaat gaagctccaa aagtaatatt ttatggagat ataaaaaaac atgaagttta
     5581 tttactctta atattatact tggcaggttt tgatgtttta tatcttaatc caaattcaaa
     5641 gagtaatata gatattttaa aatcagaaag atacaatata gagtttgaag aagccaacat
     5701 aatagaagaa aaaatttctt ttgaagaaag ggttatttta ggggaaaaaa tagataaaag
     5761 ttctgtaaaa aaagctttta ctgttggggc agaagcatca aagcgtataa gtgaggaatt
     5821 gttaaatgat gcaggattta taaaaccttg gcaactccaa gatagaaaaa taaaaaatct
     5881 acttctaagt tcaactgttg atgaaatatc aatatactgg aatcaaccac ttaaattaag
     5941 accaggattt aagtttaatg atgctattgt agaagctcca aattttcttt ctaagattaa
     6001 tggaatatat aacgataaga atgaatatat taagttttta gatttattaa gagattcgga
     6061 aagttcaaca tttattgaat ttaatggaga tgtagataga ttttcaaaag cttttacaag
     6121 agaagctttt agtttatcct ttttattgga ttcaaaaggt gcaatagata aaaactctgt
     6181 tttaaataat aaagattatt ccatatcaac actagcattg aatcaacaaa ttatgatttt
     6241 agagaaagtg gaagagttgt tagaaggaag tatgtttttg aatggtttaa gtggagaaga
     6301 caagataaaa ggtctattta cagtacttca catggataag aaatttgttc atatgatgaa
     6361 caatttcgat tactcactta taaacccaaa attgattata tacatgtaca agagtattgt
     6421 atttgataaa gaaatagttt ttcttatgct tttacttagt aagattggat ttgatattat
     6481 catattatgt ccaggaggag aaaacaatat agagaatgtt ataaataacc aattgattga
     6541 tgtacacaga ttggataaaa tggtatatga ccttaaatta aattcgcttg aaaatgatat
     6601 acctttactt aaaaaaattt ttggaaagag gagacgattt tagatgggga taaatataaa
     6661 tagtttttca aaagataaga actctgtaga ggttactgaa aatttgccta cagcagttca
     6721 agaagaaaac ttcgatataa tggaatatac aaataataaa aaaaatgaac tgagaaagtc
     6781 taaggaagtt gaggcattga catctcttat agaagtagaa aatccagata cgattttaca
     6841 gtttggtagg aaagcatctg aaggagtagc aagagtttct gatagccttt taaatacaat
     6901 aaaattaaat agaaatgaag aaaattctaa aatgttggtt catttaacta aaataatgga
     6961 caagtttgat ttagacgatt ttcaagaaac taaggaacca aatttcgttc aaaaactttt
     7021 caaaaaagct aataatgcca ttgaaatgat gtttcaaaag tatgaaacat tgggaggaga
     7081 agttgagaaa attcaaattg agcttgaaca atacgaaaga gatatagcac tttctaataa
     7141 gcaaataggt gctatgttaa atgaaaactt tgagttttac aatgaacttc aaaaatatat
     7201 tgttgctgga gaaatggcaa tagaagaaat ggataatgaa atactacctt tctttaaaca
     7261 aaaatcagag actagtggag accaaatgga tgttgtcaat tatcaagaac tattaaaagt
     7321 ttatgatatg ttaaatcaaa gagtctatga tttaaggata gcagaaaata tagctatcca
     7381 aacaatacct atgcttagag gtatgcaaca taataattat ggtttaatta gaaaaataaa
     7441 tagtgcattt gtcgtaactt taccagtatt taaacaatgt ttatctcaag ctatattact
     7501 taaaaagcaa gaattacaag caaaatctct aaaagcactt gatgacaaaa ctaatgaatt
     7561 attgcttaga aatgcacaaa atgtaagtac tcaaagtgca caaatagcta gaatggctgg
     7621 aacaagttct gttcaaatag aaacattgga aaaaatgtac aatactatca agtctggtat
     7681 agatgaaact atgagaatag aagaaaacaa tagagcttta attaaggata atacaaagag
     7741 attggaagaa ttaaatacga ctataattta taataagtag tattatatta agggctaatt
     7801 tgtataaagt tggccctttc tatgtatatg aggaggctag acattgaaat atttcgatta
     7861 tatctgcaaa gatgatttgg agagaatttt tttgaaggag ccagaagatt ttagtgctaa
     7921 gactgaaaaa gatgtgttga aatatgcact gggcgctttt ttatacgttc cagctactca
     7981 atataatatg atttataaga gtattatagg ggatgttaag ggagttagac cattagctat
     8041 ttgtttagaa gatgctgttg gagtaaatgg agagttggag gctatagaaa atcttagatt
     8101 aattttaaaa aatattagca atgaaagtat aactaataaa gatggaatac cactaatttt
     8161 tgtaagaata aaagatgtgg agcaactgtt gagaattaaa gagattataa ttaaaaatag
     8221 tcattttata acaggaatat taattcctaa agcaaattcg gagttaattg aaaattgtat
     8281 agaagcttta gattttatga atcttcaaga tatgtatgtt attccgatag tagagacaaa
     8341 agaatttata tataatgaaa aaaaagaact tagttttact aatttgtaca atgctatttt
     8401 aagacataag tcaagaatat taagcattag agtaggcata actgatatat tagggatgta
     8461 tggtataagg agagataaaa acttttctat atataataat ttgatttgtt cttcatttat
     8521 attagatata atcacatatc ttcaaagacc agagttagat atacctataa gtggtggagt
     8581 atcagaattt tttgatatga cgaataagga tataagaaat aagtatatag aagaaatatt
     8641 attggataaa tatcatggat taattggaaa gaccgtaatt catccaatgc aaattcaaat
     8701 tgtacaagcg ctatctacag tatcatatga agattttact gatgctttgg atatactgga
     8761 tagtacagac agtaagtatg gtgtgagcaa gggtgtatta ggagagagaa tgaatgaaac
     8821 aaatccacat tttttatggg ctaaaaaaac attgattcta tctaaaatat atggtgtatt
     8881 aaataaagga gtagactatg aagaattgct taaattttaa ttgtgagatt gacattattg
     8941 ataatccatt gaatttagaa ctaaatgatt ttttagacgt aggaataaga aataatagca
     9001 aaagacgttt tttgtttatc tcaaagaaac tcggtaaaca tttagcatgt aagccaagtg
     9061 agatggataa tttgggaaaa ttaatggcta caatttataa tgaaaaaaat aaggaagaat
     9121 caaatggtac tgttatagct tttgctgaaa ctggtacagc tgttgggcat agtttttttg
     9181 attacttatg tggagattat gaatttattc atactactag agagcagttt gacgagttag
     9241 aaaatctgga atttttagag gaacattccc atgcaacaga ccagaattta tactttggta
     9301 tgcttaacaa ctttaaattt ggagatgaga taatattggt tgatgatgag attaccacag
     9361 ccaatacatg catgaatata attaggaaaa ttcaaagcat ttatcctaaa aagaaataca
     9421 ctatatgctc aatactcaat tgggtaagtg atgaaaattt aagtaaagtt actcgtttag
     9481 aaagagagtt agattgtaag atagattttg tatacttatt taaaggaaac tttaaatttt
     9541 atatagatga agatattatt tcaaattaca acgataatta tagtattact aaattagaga
     9601 ctatttcaag tgataaagta aatttagtag taaatcatat ttatgttgat ttagaagatt
     9661 atattggaaa taagaaatat gtaaaatata caggaagatt tggaattaat agaagagaac
     9721 aatttagatt aaaagaaatc gttaagagag aaagtaaaaa aataactatg gccagtaaag
     9781 aatctttaaa aaatgaaaaa gaaaagattc tatttttagg tactgaagaa tttatgtata
     9841 tacctatgct gtttgcaaaa gaaaaagaaa atcaatatga tatatactat cattcaacaa
     9901 caagaagtcc aattattaat attgataaga ataattatcc tattaaaagt aaatttatgc
     9961 taaagagttt ttataatata gatattcaaa attatattta caatatagat aaacataatt
    10021 tttctaagtg ttatttattt gtagagctga ataaaagtga aaattcttat ctagaattta
    10081 ttgatataat taaaaaaaca agtataaaag aattaactat agtatgttgt agctaaagtg
    10141 ttttaacagg ataaaatata tcacgatttt aagataggag ttgagtcata tgagagattt
    10201 tagcacgtat tctaaagatg atgttatttt tttattaaaa gatatatcaa atttaattga
    10261 agaagaagga aataaagaaa gagaattaaa aatacaaaat ggtagacatt attcagaaat
    10321 gataccaata gagtatgaag ttagtgaaga ttatctgaat ttatatcatg agaaactaag
    10381 agaaaataaa gataaacttg cattttctat aggagttatg tgtgaaaaaa taattaaaaa
    10441 aaatggaaat gatgtagtac tagtttcact tgctagagca ggaacaccta ttggtatttt
    10501 ggcaaaaaga tatataagaa gcaagtataa tataagttta cctcactata caatctctat
    10561 aataagagat aagggaatag atatgaatgc aattgaatat atagtaaaga atcatccgag
    10621 ctcaaaaatt caatttttag atggatggac tggtaaggga actatatcaa aagaacttga
    10681 aaaagcatgt gatgaactta atgttaaatt taaaaaatat tttgactcaa cacttgctgt
    10741 attagctgac cctgctggat attcaggact ttatggaatt agagaagatt tcttaatacc
    10801 aagtgcatgt ttaaattcaa cagtttctgg tttagtaagt agaactgtac taagagagga
    10861 tttaattggt aaaaatgact tccatggagc taagttttat agacatttaa aagataaaga
    10921 tgaatctatg aactatatcg aaactataga agaatgtttt aaaaatcaat ttaagaatat
    10981 atctgatgaa gttgaaaact gggaaagtga cattataaca agagatggat actttgatgt
    11041 tttaaatata aaagaaaagt ataacataac agatattaac tttatcaaac caggtgtagg
    11101 ggaaacgaca agggttttac ttagaagagt tccgtataag attcttgtta aagacttaaa
    11161 tgataaatct ttagaccata tattcatatt agctaaggag aaaaatgttg aagttgaaca
    11221 aatggattta aaagcctata aatgttgtgg aataataaaa aatatgaaag atatttagga
    11281 aatatattag acaggagaat attgaatgat tgttttttca gatttagaca ggagtatcat
    11341 ttactccaat aaatttttaa atgctgatag taaatatact aatatagaaa tttataggga
    11401 aaaagaaata tcttatatat ctttagatac tataaattta ataaagcaaa tacaatatta
    11461 tggtatgttt atacctacaa ctactagaac agtggagcaa tttaagcgta tagaatttaa
    11521 taaatatggg atttattttc cttggagtat aacttcaaat ggaggagtta tacttaaaga
    11581 taatgaaata ttgaaatcat ggagtgaaaa aatagataaa ctaaaatgtg attatgagcc
    11641 cattgaaagt atgattcata aatttaaaga ctatttgaat gtagatggaa taactaattt
    11701 taaagttgca gaagatacat ttttttatat agttgttgat ttatcaagat ttaatttgga
    11761 ttcaatcaaa gaatatacaa atatattgga atcaaaaaat tggaagtttt atgtgagtgg
    11821 cagaaaaata tattttatac caaaagaaat ttcaaaagaa aatgctataa aatacttgac
    11881 taaagaatta ggaatagaat atttttatgc agttggagat tctattatgg actatggtat
    11941 gcttaatatc tcaaataaat cctatgtatt gaagcatggt gatataaata aaaatgaaat
    12001 agaaaattca tttatatcaa gttctttcaa tggaatgagt ggaactgaag agatactatc
    12061 taacatttta gacgagaact gcctacttaa tatataatga ctgatatata aataataaac
    12121 tagaaaaatc tgaaataaat tatagtaaag tttatcatac taatttattt cagattttta
    12181 tcaatttata tttaagtaag aactcaatat gttaaaatga aggtggagtc attgcccaga
    12241 ctgagataca tacctcatca tcataatttt catacacatg tggtatagta ctgttaaaat
    12301 aaaaactatc tccttcctcc aatagatatt ccttatttcc aagtgttatc ttcattttac
    12361 cttttattat atagccacat tcttctcctt cgtgtgtcac aaattcactg tttttttgtg
    12421 tatgaccatc tagtgtaaca agtataaatt ctattttttt cccagataaa ttaggaacaa
    12481 gaagttcata aaattttgta gaatcattag ttactatttt ttttcgatta tttttcttta
    12541 ctactatatc agagtcttct cttccaatct cttcaaaaaa ataacctata tttatatcaa
    12601 gagcttttga tattttccac attgctacaa tagatggaac aaccatatta cgctcaattt
    12661 gacttattaa gcctgtactt aaatctgaat tttttgctaa agtagagata cttatatttt
    12721 tagattttct aagagatcta attttgcttc caacatctat attcattaga tacaaacccc
    12781 ctcagacatg attataacat ataatttata aagattaata aaataaaaaa aaagttttac
    12841 aatacaagta ttttttatgc tatattgaat tttctgaaaa gatgcattat aatagtatta
    12901 atattcaata tattgaatat tgataacgat attttaattt aatgaaatgg aggtaattaa
    12961 gatgaagagt tttgtaagtc ctgataatat ttgggtatta tgggcagttg taactggatg
    13021 ggcagcattt agtatttatt tggaacaaaa gtacaattgg gcatcaaaag tgtcgggagc
    13081 aataatagct cttgtaggag caatgttatt atcaaatcta aatattatac cagtagagtc
    13141 tgttgtatat gaccaagtat ggggatatgt tgttccttta gccatagctt tattgttata
    13201 tcaatgtaac attaaaaaga tatggaaaga aagtggaaga ttgctcatta tatttcttgt
    13261 aggttctgta ggaactgtac ttggagctat gattggattt ttagcattaa aaaatgtagt
    13321 accagattta aatattgttg cagctatgat gacaggttct tatataggtg gaaatgtaaa
    13381 ctttgctgct atgtcagggg cgtttgatgc gccaggagaa ttagtatcag caacagttgt
    13441 agcagataat cttttaatgg cattatattt ctttgtctta atagctatac catcaattgg
    13501 attttttaga aaacatttta aacatccaca tgtagatgaa atggaaagta taggtataac
    13561 tgaaggagaa acagtagcag caaattattg gggaagaaaa gaaatatctt taaaagatat
    13621 agcaatagcc attggtagcg cctttataat tgttgcagta tctgtagaac tatcaacttg
    13681 gtttaaagct ataataccat tatcaaatcc ttttttagca atgttaaata ctttatttgg
    13741 aaatcaatat ctaataataa ctactttgac tatgttgttt gccacattta tgcctaattt
    13801 ctttggtgat ataaaaggag cacaggaatt gggtacattt ttaatatata tattctttgt
    13861 tgtagtaggt gttcctgctt caataacatt aataattcaa aaatcaccat tactactttt
    13921 atactgcgga ataatggtac taataaacat gctagttaca tttatagttg caaaaatatt
    13981 taagtttagt ttagaagaag ctattcttgc atctaatgca aatattggtg gtcctacaac
    14041 agcagcagct atggcaatat caaaaggatg gtctaagcta gtagggccaa tacttatagt
    14101 tggaacattt ggatacatag tcggtaatta ttttggtctt ttagtaggaa atattttgat
    14161 ataattttac gtgaaaaaaa gttgtttatt agaaagattt ttatttaatt ggaggttgtt
    14221 atgattttcg atggacattc agatacttgg gcagatgtaa caataagaag gcttaacggg
    14281 gaaaaagatg tatttagaag aatccatctt gataatttta aaagagcaaa tatagaagga
    14341 gctatttttg taatatggat agacccacca tatgataaag agcctgaaaa aagagttaaa
    14401 caaattataa gttctataaa agatgaaatt gaagatatga aagatgttgt aaacatagta
    14461 aaaaaatatt cagatataga taaaggtata agtgaaaaca aaataaatat tttaattggt
    14521 cttgaaggat taagccatat tggaagaaat atagatttac tagattattt ttataaagaa
    14581 gttggtgcaa gacatgcatc attaacttgg aatgaacaga atgaacttgc tacaggatgt
    14641 ttaggggatg aaaatcgtgg tttaagtgaa ataggcaaaa aagcagtcaa taaaatggaa
    14701 aaattgggca tgatagtaga tgtgtcacat ttaaatgaaa aatcattttg ggatttaatg
    14761 tctgttgcaa gtaagccagt tatagcttct cattctaatg ctaggagttt atgtgatgct
    14821 aaaagaaatc ttacagataa tcaattaaaa gaaatttcaa atacaggtgg attagttgga
    14881 ataaatagtt ttagaggatt tactaatagt aatcctaaga agcaagattt aatacatttg
    14941 gttgaccata tagactatat ggtaaatctt ataggtatag aacatgtatc ttttggtttt
    15001 gattttagtg attacttagg gaaagagact ataggttctt ttactggaaa tgctagtgtg
    15061 ccaagtgtag atggtcttga aagcacacat acagcacaga acatagtagt agagcttgaa
    15121 aatagaggtt ataaaaagaa agatatagag ttaatctcta gtggtaattt ttataggctc
    15181 tttaaagata tactaaaata atataataaa gaacttaaat t
//
LOCUS       DAYAOO010000096        15133 bp    DNA     linear   BCT 12-OCT-2024
DEFINITION  TPA_asm: Clostridioides difficile isolate ST8-SSI-h139-18
            SAMN40601845-rid21577343.denovo.097, whole genome shotgun sequence.
ACCESSION   DAYAOO010000096 DAYAOO010000000
VERSION     DAYAOO010000096.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN40601845
            Sequence Read Archive: SRR28438827
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 15133)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 15133)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-MAY-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-MAY-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002157583.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002157583.1
            Genome Coverage       :: 163x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/11/2024 16:19:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 4,038
            CDSs (total)                      :: 3,963
            Genes (coding)                    :: 3,930
            CDSs (with protein)               :: 3,930
            Genes (RNA)                       :: 75
            rRNAs                             :: 6, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 60
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 33
            CDSs (without protein)            :: 33
            Pseudo Genes (ambiguous residues) :: 0 of 33
            Pseudo Genes (frameshifted)       :: 7 of 33
            Pseudo Genes (incomplete)         :: 25 of 33
            Pseudo Genes (internal stop)      :: 11 of 33
            Pseudo Genes (multiple problems)  :: 8 of 33
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..15133
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN40601845-rid21577343.denovo.097"
                     /isolate="ST8-SSI-h139-18"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Denmark"
                     /collection_date="2018"
                     /collected_by="Statens Serum Institute"
     gene            complement(119..1006)
                     /locus_tag="ACGI5H_003248"
     CDS             complement(119..1006)
                     /locus_tag="ACGI5H_003248"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898235.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AraC family transcriptional regulator"
                     /protein_id="HFG9698938.1"
                     /translation="MAIYLEMPKLIHEFPFRTLSNEGEVLTTPHWHKEIEILLITEGV
                     VNLFINDKPMQLKKGEIVIIKGGDIHYILPSPGSERLVFQFDISFFNDLILLNEEKES
                     LINLFSSIKKCSRDWSAKIRKSVFDILIDIYNEDLYKIEGYSYAIKGKMYNLIPILYR
                     QIPREIEENTVEYEINSKEILERLNNIFKYVEKNYKQPIKLEDVSYEVGFSVYYFTKF
                     FKKNTGKTFITFLNEYRLEKAKWILLNNNISIVDLVEEVGFGSTKTFYRVFKEKIGVS
                     PLEFKKRYNSLEKKGSVSK"
     gene            complement(1106..1555)
                     /locus_tag="ACGI5H_003249"
     CDS             complement(1106..1555)
                     /locus_tag="ACGI5H_003249"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728825.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:1902495 - transmembrane transporter
                     complex [Evidence IEA];
                     GO_function: GO:0016301 - kinase activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA];
                     GO_process: GO:0016310 - phosphorylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HFG9698939.1"
                     /translation="MEIREILTEESIILDLKSTTKEGIIQELVDKLYDTGSITLKSKF
                     IKALKHREKIGSTSIGYQMAMPHGKTKYVKKASIVIGKSKKGVDWPSIDGLPVKVIIM
                     FAMPQSGGNEDMILISKIAYILGGKNIGERLLNAHTKKEILDIFYEV"
     gene            complement(1545..3452)
                     /locus_tag="ACGI5H_003250"
     CDS             complement(1545..3452)
                     /locus_tag="ACGI5H_003250"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antiterminator"
                     /protein_id="HFG9698940.1"
                     /translation="MLVSRQIEFLKLILNENKYRPIKYFKDKLNVSDKTLQKDLKMIE
                     KYLETFNIKIDIKRGYGILIEDLAKKNIDLINSLNIQSKENKSLSVEQRRMEILKYLL
                     LNSNNITSINQLADKYYVSKTSIVNDFKYIEAWIKEYNLKLNKTLEGTKIIGKEVDIR
                     KSIAKMMDDLLDENYEQHDISELTRLDSATFSALINLFDIDSIIFVETIITELEYNLG
                     YTINQPYYINLITHILICLKRIEEGNQIESQEEREISVDNLDELVYKNVTTLIDKIEN
                     RYRVKITKDEIMYIYIFLVSSGFSSENNSSYNDESDRLSESEKVSSIMIENMSRFLNI
                     NLKNDDLLQKSLASHVRPMLNRLRYDIQIKNPLLGEIQERFSDVLGLCMMTINIMTEY
                     DNLKNISIDEVSYLATYFQAAIERNMSSKRVIVVCHTGYGTSQLLAARLKREFPEWTI
                     VDIVPMHQLSKRNLDDVDFVISTVNLDLKDKLHIVVSVLLMESDINNIKNALLSKPKK
                     SMNLDTNLLGMYLEDNIYFNFDVAQMESLIGVNLGSKYESISLGKDLNIYIHKQSKLN
                     KGIMNINNVTRTIDIYLEISNQSFLKNILMEISNLYRQKNYINYIIDCKSKEDIKILF
                     KNNLLEKTNGN"
     gene            complement(3720..5615)
                     /locus_tag="ACGI5H_003251"
     CDS             complement(3720..5615)
                     /locus_tag="ACGI5H_003251"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003440068.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0022877 -
                     protein-N(PI)-phosphohistidine-fructose phosphotransferase
                     system transporter activity [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="fructose-specific PTS transporter subunit EIIC"
                     /protein_id="HFG9698941.1"
                     /translation="MIGKILRSDCIVLDKQLQTKKDVINYMANHLYHGNYINNKEKFI
                     ADINKREKESSTNMGNLIAIPHAKSNVVNQPVMMYLRTDREITDNDGQKLRSFFMIAV
                     PESGSDEHLKIISKLATYLMEENFLKHLLSAETPYEILSIFNNKAAESGDFSNNQNKG
                     LIVGITGCPTGIAHTFMAKKALEEAGQELGYEVKIETHGAIGVENKLTKEDIKRAEYV
                     IIACDKEVQLSRFIGKKVLQKKVVDAKNVSLAKNLIINAENGMAKEIKPGGKTLEDSK
                     EMLQGSEKKGVYKHLMSGVSEMIPFVVIGGIGIAIAFMFGIFASDPTHETYNPIAGFF
                     GQLGGDSAFKLFIPILAGFIAKSIAGRQGFAPAMIAGFMAVIGGSGFIGGMVAGFATG
                     YIALGVMKITENLPDVLKGVNAVLICPLLIAFTSGAIMFFVVNTPASWLNEALQSWLQ
                     SMSGTNKVLLGAILAGMMASDMGGPINKTASAFGLAMFSSNIFEPSAALMVGGMVPPL
                     AISLAMLIFKNKFTKEERKSSLPTAIMGASFITEGAIPFAAADPLRMIPANIIGSCIG
                     GAICMSLDITLMAPHGGIFVIPFACSAPVAYIACILIGTVITALIIGVTKPTIRSENS
                     EVELLGA"
     gene            complement(5651..6529)
                     /locus_tag="ACGI5H_003252"
     CDS             complement(5651..6529)
                     /locus_tag="ACGI5H_003252"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891502.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016832 - aldehyde-lyase activity
                     [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ketose-bisphosphate aldolase"
                     /protein_id="HFG9698942.1"
                     /translation="MLINMKEMLKVAQENQFAVPAFNIGSGQILKAVVQSANEKNAPV
                     ILAIHPNELSFLGDSFVASCIEEANKSKVPMVIHLDHGENKEQILRAIRCGFTSVMID
                     GSHLPYEENVAISREIVEIAKGLNVSVEGELGTIGTTGTSSEGGTDEIIYTDSKLAKD
                     FVEKTGVDTLAIAIGTAHGIYPKGFKPELKLDLLKEIREVVDIPLVLHGGSSNPDEEI
                     AQAVKLGVCKINISSDVKSAYYKKCRELLEQNPSLYEPDTIYPPCIKAAREVIEFKMN
                     LFNAIDKLKCFYKNKN"
     gene            complement(7072..7242)
                     /locus_tag="ACGI5H_003253"
     CDS             complement(7072..7242)
                     /locus_tag="ACGI5H_003253"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003440073.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9698943.1"
                     /translation="MSALLYGVCNKSISVSIVINMQEFKIGVSMAYGVLVIGICYIAL
                     GIIFKLDRKRFT"
     gene            complement(7639..7851)
                     /locus_tag="ACGI5H_003254"
     CDS             complement(7639..7851)
                     /locus_tag="ACGI5H_003254"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003440076.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HFG9698944.1"
                     /translation="MAILMKTKIKEYREKLLMTQNELAKLVGVRRETIVHLENGKYNP
                     SLKLAMDIAKVFDTTVENLFEFIEEE"
     gene            complement(7852..8268)
                     /locus_tag="ACGI5H_003255"
     CDS             complement(7852..8268)
                     /locus_tag="ACGI5H_003255"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003440086.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9698945.1"
                     /translation="MSKSETGVRSKLILELLVITYFFIAVLATKYIFKGPSTASLPGL
                     SWLIVFGCYSIYNKKYNDLVDESSEFILSKVNKIAIKIMIYSIVIISIFFATPYTSNI
                     NISNLDTGIILIAVLFIQSLSKLVLYIYFDKRGICN"
     gene            complement(8336..8749)
                     /locus_tag="ACGI5H_003256"
     CDS             complement(8336..8749)
                     /locus_tag="ACGI5H_003256"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898241.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9698946.1"
                     /translation="MSKSELGVKTNLVSELLMISYFFIDSLLKKFIFKEGNLCITFII
                     LFAFWACDFMYNKKYNDLVDEASKLMLLKVDHIASKIMLYSILLIAVFFSANYTRGLD
                     ISNLDIGVILLAILFIQSLSKLILYIHFDRKGICN"
     gene            complement(9582..10211)
                     /locus_tag="ACGI5H_003257"
     CDS             complement(9582..10211)
                     /locus_tag="ACGI5H_003257"
                     /EC_number="3.2.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421905.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008233 - peptidase activity [Evidence
                     IEA];
                     GO_function: GO:0019172 - glyoxalase III activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type 1 glutamine amidotransferase family
                     protein"
                     /protein_id="HFG9698947.1"
                     /translation="MKNRKVYMYVFDTMSDWEVAYLTAELNTGRYFKKGLKPLKVITV
                     GIDKNPIITMGGLKVLPEITVDEFNMESKDLLILPGGNTWLSMNHEIILEKVKEALRQ
                     DSIVAAICGATLGLAKKGLLDFRNHTSNDLEFLKMVIPNYSGEKYYKTESVVSDENLV
                     TASGIAPLEFTFQVLKLLDVFESEALNSWLNLYKTHDSKYFFELMNCNK"
     gene            complement(10290..11252)
                     /locus_tag="ACGI5H_003258"
     CDS             complement(10290..11252)
                     /locus_tag="ACGI5H_003258"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728634.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HFG9698948.1"
                     /translation="MAKIDNMMSILWMLNSDKKITAKQIAEKLEINIRTVYRYIDVLS
                     ASGVPIISDTGHNGGYSLLNNFTKAPLFFDIEEQKSLLHAALFAKKEGYFLDEALDKS
                     ILKLKMYSNQKQEDILTNHLRALEVIKPIGKVSIESVLKKLENSILKELSVEINYHAG
                     RKVKSKYRIINPYGIVHWNNNWYVVAFCNMRNEVRSFRVDRISEIIETSNTFNRPTEF
                     SASEFFIKGIIPEIKDEQNIIQLVIEGSIDSLDSLSQHWFLGHYLKERTPNKIIFMLE
                     EEVICKYIPNILLPYRKTIQVIEPLSLRKKIIEDLLELIDYYQI"
     gene            complement(12014..>15133)
                     /gene="cbpA"
                     /locus_tag="ACGI5H_003259"
     CDS             complement(12014..>15133)
                     /gene="cbpA"
                     /locus_tag="ACGI5H_003259"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861847.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="collagen-binding adhesin CbpA"
                     /protein_id="HFG9698949.1"
                     /translation="AGDAEGDANAVVVEEEATAEEPTSVGDFKISGGEINVDFKFASG
                     VLTILSGKQMTIQNNNPNTPTTHRIVIPKDVKAELIFDGVNIKTASNSPFTLTPDKDG
                     GAYAHVILQDGSENKLESGDVYYPGMRAGKGTTLIIDDSVVNRDIEGEFIVPEGGKIP
                     RDVTLENGDKLKKGDRLTLLDSNNRGSLKVVGNYYSAGIGGGNTESGGNIIINGGAIT
                     AIGQESSRNTGYGAGIGGGGNGSGGDITINGGIITAKGAYHGAGIGGGYYTTTKNALS
                     PSVVDPSTGSGYSGNITINGGLSYSYGGAHGSAFGDGCVNPGTNRGYRILVTGGTILP
                     YMTGVGDWIFDLSATTGDVIVTGGSLKATTFKSLGGAVAYGDLEKKTKVFMNKISLTY
                     LGQDKVSTTLVDDFKMLIDGKIYPYGAPSYTDAQGILYLWFSDQFKGSEVSVNLVVID
                     KITGEVLKPDDFYIKDIGSGSQFLKQYEEFTIDDTPPYLIIKRYDGLPFEEDVEKSFL
                     DWIFKDGGIPIITPKGEKLTDKKFMTISSQRLNEETMEPDINLGSDDLTKQVDAGKYQ
                     LSITSTQFSSIYPFKDAYWGHRAYYKAEIIPADTETSLVVEESKAKTDVFKPTDTFTL
                     NVTISPDKKEGPDCASPRGYVQFYINGKEYKDPVELKTHNKGSESHNYSTASIEWRPL
                     DSNHHIFTTEQTITVKYIGDDINYIEGSEDEKKLKLDMTNVDVDGDGIPDINIDTDGD
                     GRPDINIDTSGDWKPDINIDTDNTGEWKPSTEGGNGDGIWKPDKNIDTNGDGNPDTDY
                     NRPAIDTDNDGVDDYWKPDKNVDTGSGGYDTGNPNLNKPDPDNGGNSKPDSGNGGNSK
                     PDSGNGGNSKPDPDNGGNSKPDPDNGGNGKPDPDNGGNSKPDPDNGGNSKPDPDNGGN
                     SKPDIDTDGDGKPNINIDTDGDGKPDINIDTDGDGKPDINIDTDGDGKPDINIDIDGD
                     GKPDINIDTDGNGKPDINIDTDESLDSNVGQNVQTGDQSNIMLDLALMFISLFFLIKN
                     LTNKYLRRK"
BASE COUNT         4848 a         2666 c         1563 g         6056 t
ORIGIN      
        1 aaatagaggt tgtattgaga actaaaattt agactttata aatgaatgga attttcattg
       61 ttgaaatact gaaaatatat ttgatttcat ataaaagaaa gtgcctcatg aactaagttc
      121 attttgagac actccctttt ttctccaagc tattatatct ttttttaaat tctaatggag
      181 agactccaat tttttcttta aatactctgt aaaaagtttt tgtacttcca aaaccaactt
      241 cttcaaccaa atctacaatg gatatattgt tattaagtaa tatccacttt gctttttcta
      301 atctatattc atttaaaaaa gttataaatg tttttcctgt attttttttg aaaaatttag
      361 taaaataata tacactaaat cctacttcat aagacacatc ttctaatttt ataggttgtt
      421 tataattttt ttctacatat ttgaatatat tgttcaatct ctctaatatc tctttagagt
      481 ttatttcata ttctactgta ttttcttcaa tttctctagg aatctgtcta tataatatag
      541 gaattaaatt atacatttta ccttttattg cataactata tccttctatt ttgtataggt
      601 cttcattgta gatatctatc aatatatcga aaactgactt tcttattttt gctgaccaat
      661 ctctactaca tttttttata ctactgaata aattaattaa gctttctttc tcctcattta
      721 ataaaattaa atcattaaaa aaagatatat caaattgaaa tactaatctt tcacttcccg
      781 gtgatggcag tatataatga atatctcctc cttttattat cactatctcg ccttttttta
      841 attgcatagg cttgtcattt ataaatagat ttactacacc ttctgttata agtaatattt
      901 ctatttcctt atgccagtgt ggtgttgtta atacttctcc ttcatttgat agagtacgaa
      961 aaggaaattc atgtattaat ttaggcattt ctaaatatat tgccatatat atcctctcct
     1021 ctctagtgtc taaaaattaa tctatactat ttaaaagaat acacatttta ttttaaaaac
     1081 ctcaaattta taatttatac aatacctaca cttcataaaa tatatctaat atttcttttt
     1141 ttgtatgtgc atttaaaagt ctttcaccta tatttttacc acctaaaatg taagctattt
     1201 tagatattaa tatcatatct tcattacctc cagattgtgg catagcaaac ataattatta
     1261 cctttacagg taagccatct atacttggcc aatctacacc ttttttagat ttacctatta
     1321 ctatggatgc cttctttaca tattttgttt ttccatgtgg catggccatt tgataaccta
     1381 tactagtaga gcctattttt tctctatgtt ttaatgcctt tataaactta ctttttaaag
     1441 ttatacttcc tgtatcgtat aatttatcta ctaattcctg tattatgcct tcttttgtag
     1501 ttgatttcaa atctaaaata atgctttctt ctgttaatat ttctctaatt tccatttgtt
     1561 ttctccaata gattattctt aaataatatt ttaatatcct ctttgctctt gcaatctatt
     1621 atatagttta tatagttctt ttgcctatat aaatttgata tttccattaa aatattcttt
     1681 aaaaaacttt gattactaat ttctaaataa atatcaatcg ttctagtaac attattgata
     1741 ttcattatcc ctttatttaa tttactttgc ttatgtatat atatatttaa atcttttcct
     1801 aatgaaatag attcatattt actccctaaa ttcacaccta ttaaactttc catctgagct
     1861 acatcaaaat taaaatatat attatcttct aaatacattc ctaataagtt tgtatctaag
     1921 ttcatacttt ttttaggttt agaaagtaaa gcatttttta tattattaat atcactttcc
     1981 attaatagta ctgatacaac tatatgtaat ttatctttca aatctaagtt tacagtagat
     2041 attacaaagt ctacatcatc taaatttcgc ttactcaact gatgcatagg aactatatca
     2101 actatagtcc attcaggaaa ttctcttttt aatctggctg caaggagctg agatgttcca
     2161 tatcctgtat gacaaactac tattactctt ttactactca tatttctttc tattgccgct
     2221 tgaaaatatg tggcaagata cgaaacttca tctatactaa tattcttcag attatcatac
     2281 tctgtcataa tatttatagt catcatacat aatcccagca catctgaaaa tcgctcttgt
     2341 atctctccta acaacgggtt ttttatttgg atatcatatc ttaatctgtt taacataggc
     2401 cttacatgag atgctagact tttctgtagt aagtcatcat ttttgagatt tatatttaaa
     2461 aatcgtgaca tattctctat cattatagat gaaacttttt cactttcact taatctatct
     2521 gattcatcat tgtaactact attattttcg ctactaaatc cagatgatac caaaaaaata
     2581 tatatgtaca taatttcatc tttcgttatt tttactctgt atctattttc tatcttatct
     2641 ataagtgtag tgacattttt atatactaac tcgtccaaat tatctacaga aatttctctt
     2701 tcttcctgag attctatttg attaccttct tcgattctct ttaaacatat aagtatatgg
     2761 gtaattaaat ttatatagta gggctgattt atagtatatc ctaaattgta ttctaattct
     2821 gtaattatag tttctacaaa tataatagaa tcaatatcaa ataaatttat caatgcacta
     2881 aatgtagcag aatctaatct tgttaactca gatatatcat gttgttcata attttcatct
     2941 aataaatcat ccatcatttt ggcaatcgat ttccttatat ccacttcttt acctataatc
     3001 ttagttcctt ctaaagtttt attaagtttt aaattgtatt cttttatcca tgcctctata
     3061 tatttaaaat catttactat agaagtttta cttacataat atttatctgc taactgattt
     3121 attgaagtta tattatttga atttagcaat aaatacttta aaatctccat tcttctctgc
     3181 tctactgata aagatttatt ttccttcgat tgtatattta aactattaat taagtctatg
     3241 ttcttctttg ctaaatcttc tattaatatt ccatagcctc tttttatatc aatttttata
     3301 ttaaaagttt ctaaatattt ctcaatcatc ttcaaatctt tttgtaaagt tttatcagat
     3361 acatttaatt tatctttaaa gtattttata ggtctatatt tattttcgtt tagtatcaat
     3421 ttaagaaatt caatttgcct cgacacaagc atacttagcc ctccctacct atgtttatat
     3481 atttctatgt ttatattaag tactatttta acatatttac taactatgta aaattactaa
     3541 gatacttctg tatcataaaa gaatttatga tacaccttac taaattgata taatagataa
     3601 tataatttca aaataaaaat taaggatatt tagaaatagt taactgattc taaatatcct
     3661 tattattatt ctatatactt gttgttattc cattaattat ttttactatt atttataatt
     3721 taagcaccaa gtaattcaac ttcactattt tcactcctta tagtaggctt tgttacccct
     3781 ataatcaatg ctgttattac tgtaccaatc aatatacaag ctatatatgc aactggtgca
     3841 ctacatgcaa atggtattac aaatattccc ccatgtggtg ccattaaagt tatatctaaa
     3901 ctcatacata ttgccccacc tatacaagaa ccaattatat ttgctggaat cattcttaat
     3961 gggtctgcag ctgcaaacgg tattgcgcct tctgttatga aagatgcccc cattatagca
     4021 gttggtagag atgactttct ttcttcttta gtaaacttat ttttgaatat taacatagct
     4081 aatgatattg ctaatggagg taccattcct cctaccatta atgctgctga tggttcaaat
     4141 atattacttg aaaacatagc caatccaaaa gctgaagctg ttttattaat aggtcctccc
     4201 atatctgatg ccatcatccc tgctaatatt gcacctaata atactttatt agttccagac
     4261 atactttgta accaagattg taaagcttca tttaaccatg atgctggcgt attaactaca
     4321 aagaacatta tagctccact cgtaaatgca atcaaaagtg gacatatcaa tacagcattt
     4381 actcctttta atacatctgg taaattttct gttatcttca ttactcctaa agctatatat
     4441 cctgttgcaa aaccagctac cataccacct ataaaacctg aacctccaat aactgccata
     4501 aaaccagcta tcatagcagg agcaaatcct tgtcttcctg ctattgattt agctataaaa
     4561 ccagcaagta tcggtataaa taacttaaat gctgaatcgc ctccaagttg tccaaagaat
     4621 ccagctatag ggttgtatgt ttcatgagtt gggtctgatg caaatatacc aaacataaaa
     4681 gctatggcta taccaattcc acctatcact acaaatggaa tcatttcaga tacaccactc
     4741 attaagtgct tataaacacc ctttttctct gacccttgaa gcatttcttt tgaatcttct
     4801 aaagtctttc cacctggttt aatttcttta gccattccat tttcagcgtt tataattaaa
     4861 tttttagcta atgaaacatt cttagcatct actactttct tttgtagcac tttctttcct
     4921 ataaatctac tcagttgaac ttctttatca caagctatta ttacgtattc agctcttttt
     4981 atatcttctt tagtcaactt attttctaca cctatagctc catgagtttc tattttaact
     5041 tcatatccaa gttcttgccc tgcttcctct aatgcttttt ttgccataaa agtatgagct
     5101 atacctgttg gacatcctgt tatcccaact ataagacctt tattttgatt attactaaaa
     5161 tctcctgatt ctgcagcttt attattaaat atacttaata tttcgtatgg agtttctgca
     5221 cttagtagat gcttaagaaa attttcttcc attagatatg tagctagttt agatataatc
     5281 ttaagatgtt catctgaacc tgattctgga actgctatca taaaaaatga cctaagtttt
     5341 tgaccatcat tatctgtaat ctctctatct gttcttaaat acatcattac aggttgattt
     5401 actacatttg acttagcatg aggtatagct attaaattac ccatattagt tgatgattct
     5461 ttttcacgtt tattaatatc agctataaac ttttctttat tatttatata atttccatgg
     5521 tacaaatgat ttgccatata attaatcaca tctttttttg tttgtaattg tttatctagt
     5581 acaatacaat cgcttcgtag tattttacct atcataaatt ctcccctcct tttaatttgt
     5641 tacctcataa ttaattttta tttttataaa agcactttaa cttatctata gcattgaata
     5701 gattcatttt aaactctata acttctcttg cagcttttat acatggtgga tatatagtat
     5761 ctggctcata taagcttggg ttttgttcta atagttctct gcacttctta taatatgccg
     5821 acttaacatc actcgaaata tttattttac aaactcctag tttaactgct tgtgctattt
     5881 cttcatctgg atttgatgaa ccaccatgaa gaactaaagg tatatctact acttctctta
     5941 tttcttttaa taaatctagt ttaagctctg gtttaaaacc ttttggatat ataccatgtg
     6001 ctgtaccaat tgcaatagct agtgtgtcta ctcctgtttt ttcaacaaaa tccttagcta
     6061 attttgaatc tgtatatatt atttcatcag taccaccttc acttgatgtt cctgttgttc
     6121 ctattgttcc aagttctcct tctacggaca catttaatcc ttttgctatt tctactattt
     6181 ccctagatat agctacattc tcttcatatg gtaaatgtga gccatcaatc attactgatg
     6241 taaatccaca tcttattgcc cttaatattt gttctttatt ttccccatga tctaagtgta
     6301 ttaccatagg tactttactc ttatttgctt cttctatgca actagctaca aagctatctc
     6361 ctagaaaact tagctcattt gggtgtattg caagtattac tggtgcattt ttttcgttag
     6421 cactctgtac tactgcttta agtatttgcc cacttcctat attaaatgct ggtacagcaa
     6481 attgattttc ttgtgccact tttagcattt ccttcatgtt tattaacata ttgtacctcc
     6541 cgatatttta aattttaggt tgaatttgct tcttgttaat tttgttgttg tttatattta
     6601 aataatatca gggtaatgaa tgtcagaaaa taacaatcgt tttccttagt gaaaaggaac
     6661 ttttattata cactctaagt tccttttcac taaataattt ttagaagtct gcatcatagt
     6721 taattatatt tctcatgtac atcttctctt tttaagtgtt ttatgcttta gccttcctag
     6781 attttataat aaacaattaa gatacattaa ctataaattt aaagatactc atgcaatagt
     6841 taatgctata ttagagtcaa aaaaattaaa aagatattag ctatttggcc aatacctttt
     6901 cttggattcc aatagtatat acgatttata gaaatcttac tcacgattat ctaatgtttt
     6961 acttccataa actttacata aaacaccaaa gtgacaccct ccaaattcat ctctagctaa
     7021 taaagtgatt tggttttcta agcaccaatt tataaattag cctttgttat cttatgtaaa
     7081 tctttttcta tctaatttaa aaattattcc taatgctata tagcatatac caattactaa
     7141 tacaccataa gccatagata ctcctatctt aaattcttgc atattaatta caatagaaac
     7201 tgaaatagat ttattacaaa caccataaag caaggctgac attgtatatt atccaattgt
     7261 atgaatgaat actaatatag ctccttttaa ttaaatgatg ctatataaat catatttatc
     7321 ccaattttta atctaaccta tttatatgta tattcctttt taataaaaaa agatattgac
     7381 taaatagtca atatctttta gttgatttaa atacccacaa ttttaatcta atttttaagt
     7441 gtttccttaa cataatctta taaatattaa aatttatcta cctataaaat ttctccatta
     7501 aattttatta cattttatct taaaacaatt ataatctgac cttaatcata tattatatta
     7561 tataaatatt tttaacaaac ttaataatta aataactata ttttattatc catcttataa
     7621 atgtttataa actttccact attcttcttc aataaattca aacaaatttt ctactgtagt
     7681 atcgaatact ttagcgatat ccatagctaa cttcaaagaa ggattatatt tcccattttc
     7741 taagtgtaca atagtctcac gtcttacccc aaccaattta gcaagttcat tttgcgtcat
     7801 aaggagtttt tctctgtatt ctttaatttt tgttttcatc aatattgcca cttagttaca
     7861 tatccccctt ttatcaaagt atatatacaa cactaattta gataaagact gtataaataa
     7921 aactgcaatg aggattatac ctgtatctag gtttgatata tttatattac ttgtataagg
     7981 tgttgcaaag aaaatagata ttattactat agaatatatc attattttta ttgcaatctt
     8041 attaaccttt gatagtataa attcagatga ttcatcaact aaatcattat attttttatt
     8101 ataaattgaa taacatccaa aaactattaa ccaactcaac cctggaagag aagcagtgct
     8161 tggaccttta aaaatatact tagtggctaa tacagctata aaaaaataag ttattacaag
     8221 caactccagg ataagctttg atcttacacc agtttctgat ttagacatat aaaatcactc
     8281 cttaaaaatt atattctcta tactctttaa ttttcgtttt tatcaatatt atcacttagt
     8341 tgcatattcc ctttctatca aaatgtatat acaaaattaa tttagataaa gattgtataa
     8401 ataaaatagc taagagaatt acacctatat ccaaatttga tatatccaaa cctcttgtat
     8461 aatttgctga aaagaaaaca gctattagca aaatagaata taacattatt tttgatgcaa
     8521 tatgatcaac ctttaataac ataagttttg acgcctcgtc aactaaatca ttatattttt
     8581 tattatacat gaagtcacat gcccaaaaag cgaataaaat tataaaagta atacaaagat
     8641 ttccctcttt aaaaataaac ttttttaata atgagtctat aaaaaaatag gatatcataa
     8701 gtaactctga aacaagattt gttttaacac caagctctga tttagacata taaaatcacc
     8761 ccttaaaagt tatatattta taacacctta tgttataaat atataacttt tccaaataaa
     8821 ttgcaataga atattgaaaa tattcaataa tatcttcata aatatatttt ataaaagatt
     8881 ttataataaa cattacaata cagtactaaa ttagtttatt tcatctatca tctcaatcat
     8941 atcatttact aactattatt ctaatgagca tataacattg aaacttataa ttatacaacc
     9001 taaatgcctc ccaatgtacc ctcaaaacat catttcctgt aactgaagta taattggtat
     9061 attttatcac tgaaataaaa aaacactagt caataaagac tagtattttc aagtatttta
     9121 tcattctttt tttaattatt ggagacgaat catcagaata atgcccataa tttatctata
     9181 tgcaaattct aaatttaaaa taaagtttca gataaattta ctattctatg ctatgataca
     9241 acagaaaaaa ctgaaatcta tgagtggtag cttcatataa tcctagttcc tacagtaatc
     9301 aaaactgagg tttattctat atgtaactaa tgataaattt tattatagga gttattagat
     9361 ctatttgtgt tactataagt agtaattata tatatgataa ttttttaaca cttttctgtt
     9421 ggctatatag aaagtggttt agaatttaaa tttaaataaa atttaaattc accaaaaaga
     9481 aatctatatt agaaaccact actctattcc accagattgt aattttttgt tctttatatc
     9541 acaatgctat accatattaa attgaaaaat aagttttaaa tttatttgtt acaattcatt
     9601 aattcaaaaa aatattttga gtcatgagtt ttgtaaagat ttagccatga atttaatgct
     9661 tctgattcaa aaacatctaa aagtttcaat acttgaaacg taaattccaa cggagcaatt
     9721 cctgaagccg taactaaatt ttcatcacta actacagatt ccgttttata atatttttct
     9781 ccagagtaat ttggtattac cattttaaga aactctaagt cattacttgt atgatttcta
     9841 aaatctaata gccctttttt agctaggcct aatgtagctc cacatatggc tgcaactata
     9901 gaatcttgtc ttaaagcttc tttaactttt tctaatatta tctcatgatt catagataac
     9961 caagtatttc cccctggcaa aattaataaa tccttacttt ccatattaaa ctcatcaact
    10021 gtaatttcag gtaaaacttt taacccaccc attgttataa taggattttt atcaattcct
    10081 acagtaatta cttttagtgg ctttaatcct tttttaaaat atcttcctgt atttaattca
    10141 gcagttaaat atgccacttc ccaatctgac atagtatcaa atacatacat atatactttt
    10201 ctatttttca tcttttttac tccttatgta attaatttat atatctaatt ataaaataac
    10261 ttaactgaca tattcagtca gttaagctat taaatttgat aataatcaat taattctagt
    10321 aaatcttcaa ttattttctt cctaaggctt agtggttcaa ttacttgtat tgtctttcta
    10381 taaggtaaaa gtatatttgg tatgtacttg catattactt cctcttcaag cataaatatt
    10441 attttattag gtgttctttc tttcaagtag tgccctaaaa accaatgttg gcttaaacta
    10501 tctaaagaat ctatactccc ttctataact aattgaatta tattttgttc atcttttatt
    10561 tcaggtataa ttccttttat aaaaaattca cttgctgaaa attctgtcgg tctgttaaat
    10621 gtatttgatg tttctatgat ttcactaatc ctatccactc tgaaactacg aacctcattt
    10681 ctcatattac aaaatgcaac tacgtaccaa ttattattcc agtgaacaat tccatatgga
    10741 tttataattc tatattttga ttttacttta cgacctgcat gatagttgat ttctacagat
    10801 agctccttta atatactatt ctccaatttt ttaagtactg attctataga cactttccca
    10861 attggtttta ttacttcaag ggctcttaag tggtttgtta aaatatcttc ttgtttttga
    10921 tttgaataca tttttaactt taatatcgat ttatctaatg cttcgtctaa gaagtatcct
    10981 tcttttttag caaatagtgc tgcatgaagt agagattttt gctcttctat atcaaaaaaa
    11041 agaggtgctt tagtaaaatt atttaaaagg ctatacccac cattatgacc tgtatctgaa
    11101 attataggta ctccactcgc agaaagtaca tcaatatatc ggtacactgt tcttatattt
    11161 atttctaatt tttcagctat ctgttttgct gtaatttttt tgtcagagtt taacatccac
    11221 agtatagaca tcatattgtc aattttagcc atgtagtttc acctctttct atttgttata
    11281 taaagttatt atataacttt ttgattgatt ttttacaaaa aaacattagt aaactgctaa
    11341 taatttatac taagatttat ttcaaatatt tatagatagt ctttttctat agttaagtta
    11401 tccattaaat tacatagtag tatatctatt ttagttgata tattttcagc tacctccctt
    11461 gaatattatt acaataagtc taaatcttct ttcttccata aatatattat gaggaaagac
    11521 tatcatcttt aatggtttaa tagtataaaa gatattaatt taaaaaaatc tatttttata
    11581 tcagatgggt attgtttttt ataaaactga aaaaatcacc taatagaatc tatgattttt
    11641 taacataacc tccataaatt agttccaatt atcacttcaa attcaaattt ttatctgaag
    11701 aatatacaat catatttcca tactcaacat aatattgagt gtttggcttg tatttacaaa
    11761 ttattattct aacaaaaaca actatacata gattaaaatc atcttctaaa cataactact
    11821 aaaattgaat taatgatatc aattccatta atctctttta ataaaaaatt ctcttttcta
    11881 tatgaaaatt atttcaaaac ttttaagtta aatacaaaaa tgactataaa tagattttta
    11941 tttacacaaa tctatttata gtcactatag tttatccaat aaaataataa aataaatatg
    12001 tacacaataa atgttattta cgtcttaagt atttatttgt tagattttta attaaaaaaa
    12061 acaagctaat gaacattaat gctaaatcta gcattatatt gctttgatct cctgtttgta
    12121 cattttgacc tacattacta tctaaacttt catctgtatc tatatttata tctggttttc
    12181 cattcccatc tgtatctata tttatatccg gttttccatc tccatctata tctatattta
    12241 tatctggttt tccatctcca tctgtatcta tatttatatc tggttttcca tctccatctg
    12301 tgtctatatt tatatctggt tttccatctc catctgtgtc tatatttata ttcggttttc
    12361 catccccatc tgtatctata tctggtttgc tatttcctcc attatctggg tctggtttac
    12421 tatttccacc gttatctgga tccggtttgc tatttcctcc attatctgga tctggtttac
    12481 cattgccacc gttatctgga tctggtttgc tatttcctcc gttatctgga tccggtttgc
    12541 tatttcctcc attacctgaa tccggtttgc tatttcctcc attacctgaa tctggtttgc
    12601 tatttcctcc attatctgga tctggcttat ttagatttgg attacctgta tcataacctc
    12661 ctgagccagt atctacattt ttatcaggct tccaataatc atctactcca tcattatctg
    12721 tatctattgc tggacgatta taatctgtat cagggtttcc atctccattg gtatctatat
    12781 ttttatcagg tttccaaata ccatctccat ttccaccttc tgtactaggc ttccattcac
    12841 ctgtattatc agtatctatg ttaatatctg gcttccaatc accactcgta tctatattga
    12901 tatctggcct tccatcacca tcagtgtcta tatttatatc cggtattcca tccccatcta
    12961 catctacatt tgtcatatct aactttaact tcttttcatc ctcactacct tcaatgtaat
    13021 ttatatcatc tccaatatat tttacagtaa tagtttgttc agtagtaaaa atatgatgat
    13081 tgctatctaa aggtctccat tcaatagatg cagtactata attatgactc tcactaccct
    13141 tattatgagt ttttaattct actggatctt tatattcctt tccattaata tagaattgta
    13201 cgtaacctct tggagaggca caatctggtc cttctttctt atctggtgaa atagtaacat
    13261 ttaatgtaaa cgtatctgtt ggtttaaaaa catcagtttt agctttagac tcttctacaa
    13321 ctaatgaagt ttctgtatca gcaggaataa tttctgcctt ataatatgct ctatgccccc
    13381 aataagcatc cttaaaagga tatatactcg aaaactgtgt tgatgtaatg cttaattgat
    13441 atttcccagc atcaacttgt tttgtaagat catcacttcc taaatttata tctggttcca
    13501 tcgtttcctc atttaaacgt tgagaactaa tagtcataaa ttttttatct gtgagttttt
    13561 cacctttagg agtaattatt ggaataccac catctttaaa tatccaatct aaaaatgatt
    13621 tttctacgtc ttcttcaaat ggtaatccat catatctttt aataatcaaa tatggtggag
    13681 tatcatcaat agtaaattct tcatattgct ttaaaaattg agaacctgaa cctatatctt
    13741 taatataaaa atcatctggt tttagaactt ctccagtaat tttatctata acaactaaat
    13801 taacagatac ttcagatccc ttaaattgat cagagaacca taagtaaaga atcccttgag
    13861 catctgtata actaggtgct ccataaggat aaatttttcc atcaattagc attttaaaat
    13921 catcaactag tgtagtacta actttatctt gccctaaata cgttagagat attttattca
    13981 taaaaacttt tgttttcttt tctaaatcac cgtatgcaac tgctccacct aaacttttga
    14041 atgttgttgc ttttaatgaa ccacctgtta ctataacatc tcccgttgta gcacttaggt
    14101 caaaaatcca atctcccact cctgtcatat aaggtaaaat cgttcctcca gttacaagta
    14161 tacgatatcc tctatttgtt cctggattaa cacatccatc cccaaatgca ctaccatgtg
    14221 cacctccata tgaataggaa agtccaccat taattgtaat attcccacta taaccagaac
    14281 ctgtgctagg atctactact gagggactta atgcattctt tgttgttgta tagtatcctc
    14341 cacctattcc agctccatgg tatgcacctt tagcagttat aatacctcca ttgattgtga
    14401 tatctccacc actaccatta ccgcctccac ctattccagc tccatatcct gtattacgac
    14461 tcgattcttg acctatagca gttatagcac caccattaat aataatattt cctccacttt
    14521 cagtatttcc accaccaata cctgcagaat aataatttcc aacaactttt aaacttcctc
    14581 tattattact atctagtagt gtaaggcgat ctcctttttt taacttgtct ccattttcta
    14641 gagttacatc tctaggaatt tttccaccct caggaactat aaactctcct tcaatatctc
    14701 tatttacaac agaatcatca ataattagag tagtaccttt tcctgctctc atacctggat
    14761 aatatacatc acctgactct agcttgtttt cactaccatc ttgtaatata acatgtgcat
    14821 atgcaccacc atctttatct ggtgttaaag taaatgggct attagatgca gttttaatat
    14881 ttactccatc aaatattaat tcagctttta catctttagg tataacaatc ctatgtgttg
    14941 ttggagtatt tggattgtta ttttgaattg tcatttgttt tccactaaga atagttaaaa
    15001 cgccacttgc aaatttaaaa tcgacattta tttctccacc actaatttta aagtctccta
    15061 cagacgtagg ctcttctgca gtggcttctt cttctacaac tactgcatta gcatctcctt
    15121 ctgcatctcc tgc
//
LOCUS       DAYAOO010000097        14589 bp    DNA     linear   BCT 12-OCT-2024
DEFINITION  TPA_asm: Clostridioides difficile isolate ST8-SSI-h139-18
            SAMN40601845-rid21577343.denovo.098, whole genome shotgun sequence.
ACCESSION   DAYAOO010000097 DAYAOO010000000
VERSION     DAYAOO010000097.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN40601845
            Sequence Read Archive: SRR28438827
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 14589)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 14589)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-MAY-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-MAY-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002157583.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002157583.1
            Genome Coverage       :: 163x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/11/2024 16:19:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 4,038
            CDSs (total)                      :: 3,963
            Genes (coding)                    :: 3,930
            CDSs (with protein)               :: 3,930
            Genes (RNA)                       :: 75
            rRNAs                             :: 6, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 60
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 33
            CDSs (without protein)            :: 33
            Pseudo Genes (ambiguous residues) :: 0 of 33
            Pseudo Genes (frameshifted)       :: 7 of 33
            Pseudo Genes (incomplete)         :: 25 of 33
            Pseudo Genes (internal stop)      :: 11 of 33
            Pseudo Genes (multiple problems)  :: 8 of 33
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..14589
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN40601845-rid21577343.denovo.098"
                     /isolate="ST8-SSI-h139-18"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Denmark"
                     /collection_date="2018"
                     /collected_by="Statens Serum Institute"
     gene            complement(138..389)
                     /locus_tag="ACGI5H_003260"
     CDS             complement(138..389)
                     /locus_tag="ACGI5H_003260"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417301.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9698950.1"
                     /translation="MNRYTKIINMMGSYYTKDFEKEKKNVIKVREVKEDTVRKFFLQG
                     DCEVLVVFEDTGKEILIDDFSPEEDIKKYLGAKFINKKR"
     gene            478..1209
                     /locus_tag="ACGI5H_003261"
     CDS             478..1209
                     /locus_tag="ACGI5H_003261"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434835.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_function: GO:0051536 - iron-sulfur cluster binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="YkgJ family cysteine cluster protein"
                     /protein_id="HFG9698951.1"
                     /translation="MTSIKNKDILNCIDYSIKNKLFDKLNDVYKSLPVGNCSGCGNCC
                     MESVGINLIEFLNIFCYLEDRVDLKKSCISKILDYYFEEYTRKNPCPFKDTNNRCLIY
                     EVRPLNCRMFGHWKKEDYNKNLDNVIEKNNNYRELMKKQYGFEINDEVVNYRIDYCDR
                     FIPNKDYLSKSKRLSFFDELMILDSNIYSSGNIDIDFRDRGIVEYFIESLLYRNLAYN
                     VKIRISKEYKIRKRTIDRIKRIVLV"
     gene            1268..2179
                     /locus_tag="ACGI5H_003262"
     CDS             1268..2179
                     /locus_tag="ACGI5H_003262"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009901790.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HFG9698952.1"
                     /translation="MNLTKVKGNTFFIKGGTNTGIYVFEDNTALMIDPGLCGSRPRRV
                     NKVLDENNIQVRYIINTHGHDDHYGACNQFKEYYKDVCIMSSEYDKLYIENPELFSKY
                     IVGGKSNVFMDNILKNKMLDDIKIDKSIEAGKIELNNEMFDIIEFQGHTPGSIAVLTK
                     DNVIFVGDLLIGDEILSKYDFLFLYDIQEQINSLEKLKNIDFEYLVLGHGKQVISKED
                     SYKLIEKHLNALKKYLYQIRELLVEPKSLEILLKNIINNNNLSNNYKEYHFFKSSLVS
                     VISYLVDLEEIGYILENGELLYYTKTK"
     gene            2230..3042
                     /locus_tag="ACGI5H_003263"
     CDS             2230..3042
                     /locus_tag="ACGI5H_003263"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0015969 - guanosine tetraphosphate
                     metabolic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GTP pyrophosphokinase family protein"
                     /protein_id="HFG9698953.1"
                     /translation="MEYEKWNEILAPYEHAVEELKIKFKNIRKEYLAKGEYSPIEFVT
                     GRTKKISSIISKLKRINAKDIETEIDDIAGIRIMCQFVEDIYAIVDLIKVRNDMTIIG
                     EKDYITNYKDSGYRSYHVIIKYPINSIAGSKEIICEIQIRTLAMNFWATIEHSLKYKY
                     DHYIPETLAERLRRASDAAFLLDQEMSEIREDIMKAQAMYQMKSIAIRDTLNRIQELY
                     DLGDTHKAMQYQRKLDRTETDKNITEILELKQEIDILLEQYKDTKVDDKVVQ"
     gene            3151..3843
                     /locus_tag="ACGI5H_003264"
     CDS             3151..3843
                     /locus_tag="ACGI5H_003264"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417312.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="metallophosphoesterase"
                     /protein_id="HFG9698954.1"
                     /translation="MSLYAIGDLHFSTSVNKPMNIFGSNWDGHEKKIIDNWKEVVKEE
                     DMVLVLGDTSWGINLSEAKKDLDIISKLPGQKILIKGNHDYWWTTVTSLNKLYEDMRF
                     IQTNFYEYKDYAICGGRGWICPNDVKFDETDEKVYKREEHRLRLSLESARKSGHSKII
                     VITHYPPTNDKLEESLFTKLFEEYNVEKVIYGHLHGKESFKMGLKGIRNGVEYTLASC
                     DYTEFNLIKVHD"
     gene            3930..4871
                     /locus_tag="ACGI5H_003265"
     CDS             3930..4871
                     /locus_tag="ACGI5H_003265"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888206.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9698955.1"
                     /translation="MRWILVFIFLYLIPLVVIFRNYKNFKRSCIYSSIYVVLATTIMI
                     SNIYMSGLNKIKESMYYHNYISDETYDEKYVSNFKEKESTDLKQDNKKNEEISNNKNL
                     NNKQDRNIQNKESNEEGSNDIKEKNNSDSNVSVNNKSEKQEDNTKENNKYTSKEKNSE
                     DIKKIDMESIGIFKKEIYNIERAALVPMRECIPYTKDIAKNITKLSSIKKDVTNARNK
                     CKEVVKEYENMQIPELSKEKYTETLSNARDDVKKAYELREKSMESALKLINTKSPKYI
                     GKITEYLDLSDKQIESFKNRLNDLKEEINNSETNNIN"
     gene            4908..6065
                     /locus_tag="ACGI5H_003266"
     CDS             4908..6065
                     /locus_tag="ACGI5H_003266"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728578.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SAM-dependent methyltransferase"
                     /protein_id="HFG9698956.1"
                     /translation="MNKQSIGKLNMFFMGITQRNLDNRDFFIELEVIFKSGRKEFKGI
                     AIEEDNKYKFNFKGKSDLYTFNELLKNISKEAENYDGLVFKYVERGTIVVIEGDNKKV
                     NVKYLDNKEEVPKIDEFTASQIKNRDYYVKVGQANALLKEIGVLTKDGKIKNDKIRKY
                     NQIDHFVELIDSILKEIKDKDCITILDCACGKSYLSFVLNFYIKEVLKKNCYFIGIDY
                     SDVVIEASKNMAKNLGYKNMSFIKEDLTNYTPNRDVDLVISLHACDTATDMAIGLGIR
                     AKSEAIVVVPCCHKELLGQYRYEAMEPILKHGVFKARFADLITDGLRTLLLEGNGYDT
                     SVVEYISPLDTPKNLMIRAIKTKTNNDKALKEYKELKSQFGVEPTLEKLIY"
     gene            6217..6777
                     /locus_tag="ACGI5H_003267"
     CDS             6217..6777
                     /locus_tag="ACGI5H_003267"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009904860.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydrolase"
                     /protein_id="HFG9698957.1"
                     /translation="MNKLNICIDIDGTITSPYHFLPYLNDIFNKNITEAECITHNWEE
                     LYGSGIRDVYAEFNNKYIHSYDEAKIVEGATEVISTLSKGHNLSFVTARHECLTDVTK
                     NWLSRQGFSDIDVYLLGSDYKVEKARELSCDIFIEDNPLNSVQLADDGVKVILLDTNY
                     NKDVKHQNIVRVSNWIDIEKIIKQGI"
     gene            6805..7296
                     /locus_tag="ACGI5H_003268"
     CDS             6805..7296
                     /locus_tag="ACGI5H_003268"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417320.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9698958.1"
                     /translation="MIDLKIENRKGKIHVKSSEIKDILELRPDFEYVQDISNTINQEN
                     ILVFDCQLTGNSFDMDDLDIEEILEELGEEIDESYFSVLFEDVRAYLKDATDEIEADL
                     QDNYLFDNLRCYFDIYNINQEFTDFKFVFLVSFKDIKISSLANLAKIVSKRQLIGASK
                     FYS"
     gene            7525..8076
                     /locus_tag="ACGI5H_003269"
     CDS             7525..8076
                     /locus_tag="ACGI5H_003269"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427786.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HFG9698959.1"
                     /translation="MQSLNEIIAENLKKIRKEKHLSLDKIAQLSGVSKSMLSQIEKCE
                     VNPTISTLKKITNGLKISFTSLMERQESDIELIQKSDIDHFIEDNGKYISYPIFPFDS
                     KRRFEIFMIEIEEGGNLDSNAELPGTQEFITVFSGEVTIKINGEDYIVSSGNSIRFKA
                     DVSHIYRNSGKGIAKMSMVVYYI"
     gene            8162..9094
                     /locus_tag="ACGI5H_003270"
     CDS             8162..9094
                     /locus_tag="ACGI5H_003270"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728579.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-aminoacyl-tRNA deacylase"
                     /protein_id="HFG9698960.1"
                     /translation="MNNKKAVFFFCSDLKKDPVASNVIKCCEEIMDLNQTDIVIDDNF
                     VLEFKDKNNNLFHFVKTKDVISHNYKYYLPILNRHFRDYDFAGVVNWHEGENAPEHIL
                     TAHTIGDVPTGEFGNSNPRYFKNLINAIEDIKNENLLDEFTTLTEATHWSGTTYGEES
                     KLITEYSVPMLDIEIGSSSDSFNNSIAIQVLAKSLIRVFDCDEPLKTLLCVGGVHFEK
                     SFSDIIKNKEYNISIGHVLPNQWIVSGMYDDESGFEKLEKCINSIEGGIDCIVFHDKL
                     KGTYKEQCRKLGEKLNVPVFKHKILKNPKDLPIW"
     gene            9149..10012
                     /locus_tag="ACGI5H_003271"
     CDS             9149..10012
                     /locus_tag="ACGI5H_003271"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003431420.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0015144 - carbohydrate transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0034219 - carbohydrate transmembrane
                     transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GRP family sugar transporter"
                     /protein_id="HFG9698961.1"
                     /translation="MILSYFALLIRVVLLAFERVVVRLLGDEEGDIYKNIASSFLFFF
                     IGGVCLLPFSIMDRVSDWSFLIPCYISSLVYSIGSVAYVTSLATGEVSLVTPINSLNS
                     LFLLLLSVIFLGEGLSLAKVAGIIIMIGGVFILKKVSSFLKNVSVIFNNLPCRLMFLY
                     IFLQSVGRVLDKAFFVQVSPILYSTILYFFVGLNLFIFLAFKKKQKIICEIFTNKKGL
                     SILSGAINGYSYLALLIALNNLELSIAEPFSQVSMIITLILAHFIFKENIKEKIPGSI
                     LILIGGWLLLL"
     gene            10259..12121
                     /locus_tag="ACGI5H_003272"
     CDS             10259..12121
                     /locus_tag="ACGI5H_003272"
                     /EC_number="2.7.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728580.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_function: GO:0015573 - beta-glucoside transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA];
                     GO_process: GO:0015759 - beta-glucoside transport
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="beta-glucoside-specific PTS transporter subunit
                     IIABC"
                     /protein_id="HFG9698962.1"
                     /translation="MNYKKTAIDIIEQVGGSKNILALEHCSTRLRFKLIDRSKVNQDA
                     LKKVQGVMSIVNGAQFQVVIGNSVVDVYDEILKVCPLDTNDSTVKTEEKINLGTRFIE
                     FIINIFQPLIFAIAGAGILKSLLMLLAMFNILKSDSTIYTLLVAISDATFYFLPLMVA
                     VTTANVLKCNRLVAIAAVGYLLLPATTTALSEGVELFGFTIPNIAYNAQVFPAILCVS
                     FLATMEKIFNKYSPKPIRTFFVPMMSLAITVPITLTILGPLGYNVGTIFTTIILFLYN
                     KMGFLVVGLLAAFLPFMVATGMHKALIPYSINTIGKLGYEALYMTSSLAHNISESGAC
                     FAVALRTKDETLKQTALSAGISALMGITEPALYGITLQHKRAMLGVVFSSAISGTFLG
                     LFAVKGFVIVGPGLASMSMFIDPNNGNNLIFASIGFVIAILGSFIITLIIWKEDTNTV
                     ESSIGDVVEEELEEEKEVNILVTPVEGKVIDLSKVNDELFASKTLGDGVAIIPTNGNL
                     YAPCDSEVVMLFETKHAIGLRTKNGAEILIHIGINTVSMNGDGFKTFVKTGDNVKEGD
                     LLIQFDLDKISHANLDSTVMIVNNNGADYAYKVLNQSYGNVKKGSILFDVKGGI"
     gene            12124..13590
                     /locus_tag="ACGI5H_003273"
     CDS             12124..13590
                     /locus_tag="ACGI5H_003273"
                     /EC_number="3.2.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895420.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016798 - hydrolase activity, acting on
                     glycosyl bonds [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
                     /protein_id="HFG9698963.1"
                     /translation="MRKFPEGFLWGGATAANQFEGGWNLGGKGWSVSDVAKAHFDADV
                     KDYKSNNEITTKDIEEGLAHPEDEVNYPKRHGSDFYHHYKEDIALMAEMGFKTYRMSI
                     AWSRIFPNGDDKEPNEEGLQFYDDVFDELISYGIEPLVTMSHYEPPLNIVLNYDGWYS
                     RQVINMFVRYVETICERYKNKVKYWLTFNEVDSMIRHPYTTGGLVRDRFKDKNFEEVI
                     FQAMHHQFVASAIATKICHEIIPNSKVGCMLTKLTYYPYTCRPEDVLATQQKMRSIYA
                     YSDTQVFGEYPVYLLSYFKNNNIQIVKEEHDDEIMKKYPVDFISFSYYMSSCEAADTT
                     GLDITPGNTLLAVKNPYLEMSEWGWQIDSIGLRISLIELYDRYRKPLFIVENGLGAKD
                     ILTEDKKVHDQYRINYLKEHFKCMLDAIIEDGVELWGYTSWGCIDLVSESTKQMSKRY
                     GYIYVDADDYGKGTYNRYKKDSFYWYKKVIENNSIDFK"
     gene            13614..14450
                     /locus_tag="ACGI5H_003274"
     CDS             13614..14450
                     /locus_tag="ACGI5H_003274"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434860.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HFG9698964.1"
                     /translation="MNYIIKKVLNSSVVLVHDAKYNEFILLGKGIGYGKKTGEYICGS
                     NDNQMFVPVENTKSKQFLELMDDIPVDILKITQEIIVEAEKLLNSSFNKNLYLILADH
                     FNFAIERMRKGIKITNRVFWEIKNYYPNEFKVGMVAIYMVEERLGIQLPEEEAANIAF
                     HFANAMASDGNSYDTIKYAKVIGEIINIFVFSLNRTLDKKSMHYMRFITHIKFFVERF
                     FSDSMLSSGDDLLFNQMKRSNPKEMLIALKVRDFLEKKYGKKLTNEEIAFLVVHIARV
                     KQ"
BASE COUNT         5757 a         1422 c         2577 g         4833 t
ORIGIN      
        1 tggaattatt ttacaaaaaa tagaaaaaaa gctatcttaa agtctaaaaa agcaataaaa
       61 gataactttt aactataatt atatagaatt ataactgtac atttattaaa ttttaatttt
      121 agaattattt ttgataacta tcttttttta tttataaatt ttgctcctaa atattttttg
      181 atatcttctt caggagaaaa gtcatcaata agtatttctt tcccagtgtc ttcaaatact
      241 acaagaactt cacagtcacc ttgtaagaaa aattttctaa ctgtatcttc tttaacttct
      301 ctaactttta ttacattctt tttttctttt tcaaagtctt ttgtgtaata acttcccatc
      361 atattaatta tttttgtata tctattcata aaatacctcc atatgcgatt aaatttaaaa
      421 aatatgttat aataattgtt tgtattaact taataattat aacaaggagt aataataatg
      481 actagtataa aaaataaaga tattttaaat tgtatagatt attccattaa aaataagctc
      541 tttgacaaac taaatgatgt atataagtcc ttgccagtag gaaattgttc tggatgtgga
      601 aattgttgta tggagtcagt aggtataaat ttaattgagt tcttgaatat attttgttat
      661 cttgaagata gagttgattt aaaaaaaagc tgtataagta aaatattaga ttattatttt
      721 gaggagtata caagaaagaa cccatgtcca tttaaagata ctaataatag atgtttaata
      781 tatgaagtta gaccattaaa ttgtaggatg tttggacatt ggaaaaaaga ggattataat
      841 aaaaatttag ataatgttat tgagaaaaat aataactata gagagttaat gaaaaagcaa
      901 tatggatttg aaataaatga tgaagtagta aattacagga tagattattg tgatagattt
      961 attccaaata aagattattt aagtaaatct aagagattaa gcttttttga tgagcttatg
     1021 atattagact caaatattta ttcaagtgga aatatagata tagactttag ggatagaggt
     1081 atagttgaat attttataga gtcattactt tatagaaatt tagcatataa tgtgaaaata
     1141 aggatatcta aagaatacaa aataagaaaa agaactatag atagaataaa aaggattgtt
     1201 cttgtatagt tttatattag taagtaataa attgtatcat aaatattgtc aaaatgaggt
     1261 gaagaaggtg aatcttacaa aagtaaaagg aaataccttt tttataaaag gtggcacgaa
     1321 tacaggaata tatgtatttg aagataacac agcacttatg atagacccag ggttatgtgg
     1381 ttcaagacct aggagagtaa ataaagtatt agatgaaaat aatatacagg ttagatatat
     1441 tataaatact catggtcatg atgaccacta tggagcttgt aatcaattta aagaatatta
     1501 taaagatgtg tgtataatgt catctgaata cgataaatta tatatagaaa atccagaatt
     1561 gttttcaaag tatattgttg ggggaaagag caatgtattt atggataata tcttaaaaaa
     1621 taaaatgttg gatgatataa aaatagataa atctatagaa gctggaaaaa ttgaattaaa
     1681 caatgaaatg tttgatataa ttgaatttca gggtcataca cctggtagta tagctgtttt
     1741 gacgaaggat aatgtgattt ttgttggcga tttattgata ggagatgaaa ttctatcaaa
     1801 atacgatttc ttgtttctat atgatataca agaacaaata aattcattag aaaaattaaa
     1861 aaatatagat tttgagtact tagttttagg gcatggcaag caagttatat cgaaagaaga
     1921 ttcttataaa ttaatagaaa aacatttgaa tgctttaaaa aaatatttat atcaaataag
     1981 agagttgctt gtagaaccga aatctttaga aattttatta aaaaacatta taaataacaa
     2041 taatttaagc aataattata aagagtatca tttttttaaa tcttcgttag tatctgtcat
     2101 aagttactta gttgatttag aagaaatagg gtatatattg gaaaatggag aattgcttta
     2161 ctatacaaaa acaaaataaa ttatgataaa ataaagaagg tcataaaaaa caaataaagg
     2221 gtgagcaata tggaatacga aaaatggaat gagatactag caccttatga acatgcagta
     2281 gaggaattga aaataaaatt taaaaatata agaaaagaat atttagcaaa aggtgaatat
     2341 tctcccatag agtttgtcac aggtagaaca aaaaaaatat cttccataat atctaagtta
     2401 aaaaggataa atgcaaaaga tatagaaact gaaattgatg atattgctgg tataagaata
     2461 atgtgccagt ttgttgagga tatatatgct atagttgatt tgataaaagt aagaaatgat
     2521 atgactataa taggagaaaa agattatatt acaaattaca aagatagtgg ttatagaagc
     2581 tatcatgtta taataaaata ccctataaac tccattgcgg gttcaaagga aattatatgt
     2641 gaaatacaaa taagaactct tgcaatgaat ttctgggcta caatagaaca ttcattaaaa
     2701 tataaatatg accattacat acctgagact cttgctgaaa ggcttagaag agcatctgat
     2761 gctgcctttc ttttagacca agaaatgagt gaaataagag aggacataat gaaagctcag
     2821 gctatgtacc aaatgaagtc tatagctatt agagatactt taaatagaat acaagagtta
     2881 tatgacttgg gtgatacaca taaagctatg cagtaccaaa gaaaacttga tagaactgaa
     2941 acagataaaa atataactga aattttggaa ttaaaacaag aaatagatat attattagag
     3001 caatataagg atactaaggt agatgataaa gtagttcagt aaaaactact tgtagaaaat
     3061 ttgctaaata ttaatggggc tgcctcttaa tggaaaataa tttctaaaaa gagacagcct
     3121 atttagtgta attaagaaag gaatgatatt atgagtttgt atgctatagg tgatttacat
     3181 ttttcaacat cagtcaataa gccaatgaat atctttggaa gtaattggga tggtcatgaa
     3241 aagaaaatta tagataattg gaaagaagtt gttaaggaag aagatatggt cttagtacta
     3301 ggagatacat cttggggaat taatttatcc gaagctaaaa aagatttaga tataataagc
     3361 aaacttccag gtcagaaaat acttataaag ggaaatcatg attactggtg gacaaccgtt
     3421 acaagtttaa ataagctata tgaagacatg cgttttattc agacaaattt ttatgaatat
     3481 aaagattatg caatttgtgg aggtaggggc tggatatgtc ctaatgatgt taaatttgat
     3541 gagactgatg aaaaagttta taaaagagaa gaacatagac ttagactatc attagaatct
     3601 gctcgtaaaa gtggtcactc aaaaataatt gtgattactc attatcctcc tacgaatgat
     3661 aaattggaag aatctttatt tacaaagtta tttgaagaat ataatgttga aaaggtgatt
     3721 tatggtcact tgcatggtaa agaatctttt aaaatgggat tgaaggggat tcgaaatgga
     3781 gtagaatata cattagcatc ttgtgactat acagaattta atttaataaa agttcacgat
     3841 taaaaaacat aaattggtaa atactataag atacatgatt aaaaataaat atttgaggga
     3901 tttcggtttt gagaaaggag acacgactta tgaggtggat attagttttt atatttttat
     3961 atcttattcc tttagtagtg atattcagaa attacaagaa ttttaagagg tcttgtatct
     4021 acagtagtat ttatgtggta ttagctacaa caataatgat aagtaatatt tatatgagtg
     4081 gacttaataa aataaaagag tctatgtatt atcacaatta tatttctgat gagacatatg
     4141 atgaaaagta tgtatcaaat tttaaggaaa aagaaagtac tgatttaaaa caggataata
     4201 aaaagaatga agaaatatca aataataaaa atttaaacaa caaacaagat agaaatatac
     4261 aaaataaaga aagtaatgaa gaaggaagta atgatataaa agaaaagaat aattctgata
     4321 gtaatgtttc agtgaataat aaatcagaaa aacaagaaga taatacaaaa gaaaataata
     4381 aatatacaag taaagaaaaa aatagtgaag atataaaaaa aatagatatg gaaagtatag
     4441 gaatttttaa gaaagaaatt tataatatag aaagagcagc tttagttcca atgagagaat
     4501 gtatacctta cactaaggat atagcaaaaa atataactaa attatctagt ataaaaaaag
     4561 atgttacaaa tgccagaaac aagtgtaaag aagttgtaaa agaatatgaa aatatgcaga
     4621 ttccagaact ttctaaggag aagtatacag aaacattgag taatgctaga gatgacgtaa
     4681 agaaagcata tgagcttaga gaaaaatcta tggaaagtgc tttgaaatta ataaatacta
     4741 aaagccctaa atatataggg aagataacag aatatcttga tttatcagat aagcagatag
     4801 aaagttttaa aaatagattg aacgatttaa aagaagaaat aaataattca gaaacaaata
     4861 atattaatta ataagattta aagatataag ttaaaaggga gattatgatg aataaacaga
     4921 gtataggaaa actaaatatg ttttttatgg ggattactca aagaaacctt gataataggg
     4981 atttttttat tgagttagag gtgattttta aatctggaag aaaagagttt aaaggaattg
     5041 caatagagga agataataaa tataaattta attttaaagg aaaatcagat ttatatacgt
     5101 ttaatgagtt gcttaagaat atttctaaag aggcagaaaa ttatgatgga ttagtattta
     5161 aatatgttga gcgaggaact attgttgtaa ttgaaggaga caataagaag gtaaatgtaa
     5221 aatatttaga taataaggaa gaagtaccta aaatagatga atttacggca tctcaaataa
     5281 aaaacagaga ttattatgta aaagtaggac aagcaaatgc acttttaaaa gaaattggag
     5341 tacttacaaa agatggtaag ataaaaaatg ataaaataag aaaatacaat cagatagacc
     5401 attttgttga attgatagat agtattttaa aagaaataaa ggataaagac tgtataacta
     5461 tcttggattg tgcttgtgga aaatcttact taagctttgt cttaaatttt tatataaaag
     5521 aagtattgaa gaaaaactgt tattttatag gaatagatta ttcagatgta gttatagaag
     5581 catcaaaaaa tatggctaaa aacttgggtt ataaaaatat gtcatttata aaagaggatt
     5641 tgactaatta tacacctaat agggatgttg accttgtaat aagtctacat gcttgtgata
     5701 cagctacaga tatggcaata ggtctaggaa ttagagcaaa atctgaagct atagtagtag
     5761 taccatgttg tcataaggag ttattagggc aatatagata tgaagctatg gaaccaatat
     5821 taaaacatgg tgtatttaaa gctagatttg cagatttaat aactgatggt ttaagaacat
     5881 tgttattgga gggcaatgga tatgatactt ctgtagtaga atacatatct ccacttgata
     5941 caccaaaaaa tttaatgata agagcgataa aaactaaaac gaataatgac aaagcattaa
     6001 aagaatataa agaactgaaa tcacaatttg gagtggaacc aaccttagaa aaacttatat
     6061 attagttaaa aatgtaaaat ttacgaaaag cttgcttaaa tatgcaagct ttttggtatt
     6121 atataggtat agtcatatcc agagttttga tttataatta aagctgtgct ataatatttg
     6181 attaatcaaa tcaataaatg ttacatggag gtaaaaatga acaaattgaa tatatgtatt
     6241 gatatagatg gaacaataac aagcccttat cattttcttc catacctaaa tgatatcttt
     6301 aataaaaata taactgaagc agagtgtata acacataatt gggaagaatt gtatggttcg
     6361 ggaataagag atgtgtatgc ggagtttaat aataagtata tacactcata tgatgaagca
     6421 aagattgtag agggtgctac agaggtaatt agcacattat ctaaaggaca taatttatct
     6481 tttgtaacgg ctagacatga gtgtttaact gatgtaacta aaaattggct atcgagacaa
     6541 ggattttcag atatagatgt ttacttatta ggaagtgatt ataaagttga aaaggcaaga
     6601 gaactgagtt gtgacatatt tatagaagat aatcctttaa actcagtgca actagctgat
     6661 gatggtgtta aagtaatact tctggatact aactataata aagatgttaa acatcaaaat
     6721 atagttagag ttagtaattg gatagatatt gaaaagatta taaaacaagg tatttaaaga
     6781 tttgtagatt gaaaggggga gcatatgata gatttaaaaa ttgaaaatag aaaaggaaaa
     6841 atccatgtaa agagcagtga aataaaagac attttagaat tacgtccaga cttcgaatat
     6901 gtacaagata tatcaaatac tataaatcaa gaaaatatat tggtatttga ttgccagttg
     6961 acaggaaatt cttttgatat ggatgattta gatatagaag aaatattgga agagttaggt
     7021 gaagaaatag atgagtctta tttcagtgtt ttatttgaag atgtaagagc gtatttaaaa
     7081 gatgctactg atgagataga agcagactta caggataatt acttatttga taatttgaga
     7141 tgttattttg atatatacaa tataaatcaa gaatttacag attttaagtt tgtattttta
     7201 gtttctttta aagatataaa aatttcttca ttagcaaacc tagctaagat tgtttctaag
     7261 agacagctta taggtgcatc taagttttat agttaaaatg aaatattatt ataataaaag
     7321 ctagtaacct tgtaaaaata taggttacta gttttttatt tattcatttt cacaaaattt
     7381 cagaaaacta tttacattct aaaaaaagta atgtatatta aacataatgt acattataat
     7441 ggataaaaag tttctattaa attactaagt ttatttaata atcaaaataa tttatcttat
     7501 attagtatgt attagggggt atttatgcaa agtttaaatg aaataattgc tgaaaattta
     7561 aaaaagataa ggaaagaaaa acatcttagt ttagacaaga ttgcacaact tagtggtgta
     7621 agtaagagta tgctatctca aattgaaaag tgtgaggtaa atcctactat atctactttg
     7681 aagaaaataa ctaatgggct aaaaatttca tttacatcat tgatggagag gcaggaaagt
     7741 gacatagaat tgattcaaaa aagtgatata gaccatttta ttgaagataa tggaaagtat
     7801 ataagttatc caatatttcc atttgactcc aaaagaagat ttgagatatt tatgattgaa
     7861 atagaagaag gtggaaattt agattcaaat gctgaacttc caggaacaca agagtttata
     7921 actgttttta gtggcgaagt aaccattaaa ataaatggag aagattacat tgtatctagt
     7981 ggaaattcta taagatttaa agctgatgta tcacatatat atagaaactc aggcaaaggt
     8041 atagctaaaa tgagtatggt agtatattat atataaataa tttaatggaa ttagagtgat
     8101 atttagatga ttttaggtat gaagatatat tatatttaag ttataggagt gtgatttatg
     8161 gatgaataat aaaaaagcag tttttttctt ttgcagtgat ttaaagaaag acccagtagc
     8221 cagtaatgtg ataaaatgtt gtgaagaaat aatggattta aatcaaactg atattgttat
     8281 tgatgataat tttgtattag agtttaagga taaaaacaat aacttatttc attttgtaaa
     8341 aacaaaagat gtaataagtc ataattataa atattatctt ccaattttaa atagacattt
     8401 tagagattat gattttgcag gagttgtaaa ttggcatgag ggagaaaatg ctccagaaca
     8461 tatcctaaca gctcatacaa ttggagatgt tccaacagga gaatttggaa attcaaatcc
     8521 aagatacttt aaaaatctaa tcaatgctat tgaggatata aaaaatgaaa atctacttga
     8581 tgaatttact acattaacag aagcaactca ctggtctgga acaacatatg gtgaagaatc
     8641 taaattaatt acagaatatt ctgtacctat gttggatatt gagataggaa gtagtagtga
     8701 tagttttaat aatagtatag caatacaggt attggcaaaa tcattaatta gagtatttga
     8761 ttgtgatgaa cctttgaaga ctttgttatg tgttggaggg gtacattttg agaaatcttt
     8821 ctcagatatt ataaaaaata aagaatataa catatcaatt ggacatgtat tgccaaatca
     8881 atggattgta agtggaatgt atgatgatga atctggattt gagaaactag aaaagtgtat
     8941 aaatagcatt gaaggaggaa ttgattgtat agtttttcat gataaattaa aaggtaccta
     9001 taaagagcaa tgccgtaaac taggtgaaaa acttaatgta cctgtattta aacataaaat
     9061 attaaaaaat ccaaaagact tacctatatg gtagtcttat acagttaata taacaataag
     9121 tcggattaat ttttaagcga ggtcaaaaat gatattatct tattttgcat tattaattag
     9181 agtagtgcta ttagcttttg aaagagtagt tgtaagatta ttaggtgatg aagaaggaga
     9241 tatttataaa aatatagctt catcatttct atttttcttt atagggggag tatgtttact
     9301 tccatttagc ataatggata gagttagtga ttggtcgttt ttaataccat gttatataag
     9361 tagtttagtc tattcaattg gttcagtagc gtatgtaacg tctttagcaa ctggggaagt
     9421 ttcacttgtt actccaataa atagtttaaa ttcattgttt ttactgcttt tatcagttat
     9481 atttttaggt gaaggtttaa gtttagcaaa agttgcagga atcataatta tgattggtgg
     9541 agtgtttata ttaaaaaaag taagttcttt tttaaagaat gtctctgtaa tttttaacaa
     9601 tttaccatgt agattaatgt ttttatacat atttttgcag tcagtaggaa gagtattgga
     9661 taaggctttt tttgtacaag tatctcctat attatattca actatactgt attttttcgt
     9721 aggtttaaat ttatttatct ttttagcatt taaaaagaaa caaaaaataa tttgtgagat
     9781 ttttactaat aaaaaggggc tttcaatttt aagtggtgct attaatggat attcttattt
     9841 agcattatta attgctttaa ataatctaga acttagtata gcagagccat tttctcaagt
     9901 atctatgata ataactttaa tacttgctca ttttatattc aaagaaaata taaaagaaaa
     9961 aataccaggt tcaattttga tactaattgg tgggtggcta ctgttacttt aattgacata
    10021 aaaaatgaat tataaaggtg ctattagtta gtatcagaaa atttaaaaaa gtattgacaa
    10081 ttcttttagg caaatgttaa tataataata caaaatagta taaatagaag acatgttact
    10141 ggtaatgcag gcaggatcga atatattgct ttgatttttc aaggtgttta tataggttct
    10201 gccttttttg catcttgaat ggccattcat aaaaaattat ggagaaggag attacaagat
    10261 gaattataaa aaaactgcca ttgacattat tgaacaagtt ggtggttcaa aaaatatttt
    10321 agctttagaa cactgttcaa ctagactacg ctttaagttg attgatagaa gtaaagtcaa
    10381 tcaagatgct ttaaaaaaag tacaaggtgt tatgagtata gttaatgggg cacaatttca
    10441 agttgtcatt ggaaatagtg ttgttgatgt gtatgatgaa attttaaaag tttgcccttt
    10501 agatacaaat gatagtactg taaaaactga agaaaaaata aacttaggaa caagatttat
    10561 agaatttatt attaatattt ttcaaccact gatttttgct attgcaggag ctggtatttt
    10621 aaaatcactg ttgatgttat tagcaatgtt taatatttta aaatcagatt ctactatata
    10681 tacattatta gttgctattt cagatgcaac attctatttc ctacctctta tggtagctgt
    10741 aactactgcc aatgtattga aatgtaatcg tttagtagct attgccgctg taggatactt
    10801 attgcttcca gcaacaacaa ctgctttaag tgaaggtgtt gaactatttg gatttacaat
    10861 tccaaacatt gcctataatg cacaggtttt cccggctatc ttatgtgtgt ctttcttggc
    10921 aacaatggag aaaattttta acaagtattc accaaaacca attcgaactt tctttgttcc
    10981 tatgatgtct ttggcaatta ctgttccaat tactctaact attttaggtc ctttaggata
    11041 taacgttggt acaattttta caaccattat tttattctta tataacaaaa tgggattctt
    11101 agttgtagga ttacttgctg cttttcttcc atttatggtt gcaacaggaa tgcacaaagc
    11161 actaatacct tattcaatta atacaattgg aaagttgggt tatgaagctt tatatatgac
    11221 atcttcatta gcccacaata tttctgaaag tggtgcttgt tttgcagtag ccttgcgaac
    11281 aaaagatgaa acattaaaac aaacagcatt atctgcagga atttctgcct tgatgggaat
    11341 tacagagcca gctttatatg gtattacctt acaacataaa agagcaatgt taggtgttgt
    11401 attctcaagt gcaatttctg gtaccttttt aggattattt gcagtaaaag gatttgtaat
    11461 tgttggacca gggcttgcca gtatgagtat gtttattgac ccaaacaatg gaaacaattt
    11521 gatttttgcg agtattggtt ttgttattgc aatattaggc tcgtttatta ttacactgat
    11581 tatttggaag gaagatacaa atacagtaga gtcatcaatt ggagatgttg ttgaagaaga
    11641 gctagaagaa gaaaaagaag taaatatctt agtaactcca gtagaaggaa aagtaataga
    11701 tttaagtaag gttaatgatg aactatttgc aagtaagact ttgggagatg gagttgcaat
    11761 tataccaacc aatggaaatt tatacgcacc ttgtgattca gaagttgtga tgttatttga
    11821 aacaaaacat gcaattggtt taagaacaaa aaatggggct gagattttga ttcatattgg
    11881 aataaatact gtaagtatga atggagatgg atttaaaaca tttgttaaga caggcgataa
    11941 tgtaaaagaa ggagatttat taattcaatt tgatttagac aaaatctcac atgctaattt
    12001 agattcaact gttatgattg taaacaataa tggagcagat tatgcttata aagtgttaaa
    12061 ccagtcttat ggcaatgtaa aaaaaggaag tatcttgttt gatgtaaagg gaggaatata
    12121 aatatgagaa aatttccaga aggatttctt tggggaggag ctacagctgc taatcaattt
    12181 gaaggtggtt ggaatttagg tgggaaaggg tggtctgtat cagatgtagc aaaggcacac
    12241 tttgatgcag atgtgaaaga ttataaatct aataatgaaa tcacaacaaa agatatagaa
    12301 gaaggattag cacatcctga agatgaagta aattatccaa aacgtcatgg tagtgatttt
    12361 tatcatcact ataaagaaga tattgctcta atggcagaaa tgggatttaa gacatatcga
    12421 atgagtattg cttggtctcg tatttttcca aatggagatg ataaagagcc aaatgaagaa
    12481 ggtttacagt tttatgatga tgtatttgat gagttgataa gttatggaat tgaaccactt
    12541 gttactatgt cacattatga accaccatta aatatcgttt taaactatga tggatggtat
    12601 tcacgacaag ttatcaatat gtttgttagg tatgtagaaa ctatctgtga aagatataaa
    12661 aacaaagtga aatattggct tacatttaat gaagttgatt ctatgattcg tcatccgtac
    12721 actactggtg gtttagttcg agaccgtttt aaggataaaa actttgagga agttattttt
    12781 caagctatgc atcatcaatt tgtagctagt gccattgcaa caaaaatttg ccatgagatt
    12841 attccaaatt caaaagtagg gtgtatgtta acaaaattaa cgtattatcc atatacatgt
    12901 agaccagaag atgttttggc aactcaacaa aaaatgagaa gtatttatgc atatagtgat
    12961 acgcaggttt ttggtgagta tccagtatat ttactgtcgt attttaaaaa taataacatt
    13021 caaatagtaa aagaagaaca tgatgatgaa attatgaaaa agtatccagt agattttatt
    13081 tcattctctt actatatgtc ttcttgtgag gcagctgata caactggatt agatattaca
    13141 cctgggaata cgttattagc tgtaaaaaat ccttatttag aaatgagtga atggggttgg
    13201 caaattgatt caataggtct acgtatatct ttgattgaat tatatgatag atacagaaag
    13261 cctttattta tagttgaaaa tggattggga gctaaagata ttttaactga agataaaaaa
    13321 gttcatgacc aatatagaat taattattta aaagaacact ttaaatgtat gttagatgcg
    13381 attatcgaag atggcgttga actttgggga tatacttcat ggggttgtat tgatttggtc
    13441 agtgaatcaa cgaaacaaat gtcaaaacgt tatggatata tttatgtgga tgctgatgac
    13501 tatggaaagg ggacatataa tcgatataag aaagatagtt tttattggta taaaaaggta
    13561 attgaaaata atagtataga ttttaaatga ccaatagaag gtgagcaaat aaaatgaact
    13621 acataataaa gaaagttttg aactcgagcg ttgttttagt tcatgatgca aagtataatg
    13681 aatttatttt gctagggaaa ggaattggat atggtaaaaa aacaggagaa tatatttgtg
    13741 gttccaatga taatcaaatg tttgtccctg ttgaaaatac aaaatcaaaa caatttttag
    13801 aattaatgga tgatattcct gtcgacattt taaagataac acaggaaata atagtagagg
    13861 cagaaaagtt attgaactca tcttttaata aaaacttata cttaatatta gcagaccatt
    13921 ttaactttgc aattgaaagg atgcgtaaag gaataaaaat tacaaatcga gtattttggg
    13981 aaataaaaaa ttattatcca aatgagttta aggttggaat ggttgcaatt tatatggtag
    14041 aggagagatt gggcattcaa ttaccagagg aagaagcagc taacattgct ttccattttg
    14101 caaatgctat ggcttcagat ggaaattcat atgatacgat taagtatgcc aaagtaattg
    14161 gagaaataat taatattttt gttttttctt tgaatagaac cttagataaa aagagtatgc
    14221 attatatgag atttataaca catataaaat tttttgtgga aagatttttt tcagatagta
    14281 tgttaagcag tggtgatgat ttattattta atcaaatgaa aaggtcaaat ccaaaagaaa
    14341 tgttaattgc attaaaagtt agagattttt tagaaaagaa atatggaaaa aagttaacaa
    14401 atgaggaaat agctttcttg gttgtacata tcgcacgagt taagcaatag agtgaattac
    14461 taatattatc ttatacgtct acatggtaga aaattgaaag aaggtaaagt atataaagaa
    14521 actgagacat attattttgt tgttcattat gtttatttta tgagtgtatc ctgttaaaaa
    14581 tttaagtta
//
LOCUS       DAYAOO010000098        14126 bp    DNA     linear   BCT 12-OCT-2024
DEFINITION  TPA_asm: Clostridioides difficile isolate ST8-SSI-h139-18
            SAMN40601845-rid21577343.denovo.099, whole genome shotgun sequence.
ACCESSION   DAYAOO010000098 DAYAOO010000000
VERSION     DAYAOO010000098.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN40601845
            Sequence Read Archive: SRR28438827
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 14126)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 14126)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-MAY-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-MAY-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002157583.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002157583.1
            Genome Coverage       :: 163x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/11/2024 16:19:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 4,038
            CDSs (total)                      :: 3,963
            Genes (coding)                    :: 3,930
            CDSs (with protein)               :: 3,930
            Genes (RNA)                       :: 75
            rRNAs                             :: 6, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 60
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 33
            CDSs (without protein)            :: 33
            Pseudo Genes (ambiguous residues) :: 0 of 33
            Pseudo Genes (frameshifted)       :: 7 of 33
            Pseudo Genes (incomplete)         :: 25 of 33
            Pseudo Genes (internal stop)      :: 11 of 33
            Pseudo Genes (multiple problems)  :: 8 of 33
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..14126
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN40601845-rid21577343.denovo.099"
                     /isolate="ST8-SSI-h139-18"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Denmark"
                     /collection_date="2018"
                     /collected_by="Statens Serum Institute"
     gene            499..1392
                     /locus_tag="ACGI5H_003275"
     CDS             499..1392
                     /locus_tag="ACGI5H_003275"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889384.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sulfide/dihydroorotate dehydrogenase-like
                     FAD/NAD-binding protein"
                     /protein_id="HFG9698965.1"
                     /translation="MSNKIVSKRQLTDSIYLMEIEAPRVAKSSQPGQFIIIKNDEKGE
                     RIPLTIADYDREKGTVTIVFQTVGASTKKLAMFEENDFVMDFVGPLGQASEFIHEDIE
                     ELRNKKILFVAGGVGSAPVYPQVKWFKEHGLDVDVIIGARTKELIILEDDMKKVAKNV
                     YVSTDDGTYGFNGRVTDLLKDLVDNQGKKYDQAIVIGPMIMMKFMCQLTKELNIPTIV
                     SLNTIMIDGTGMCGGCRVSVGNETKFACVDGPEFDGHLVDFDQAMRRQSMYKTQEGRA
                     MLKLEEGDSHHHSNCGCGGNK"
     gene            1392..2786
                     /gene="gltA"
                     /locus_tag="ACGI5H_003276"
     CDS             1392..2786
                     /gene="gltA"
                     /locus_tag="ACGI5H_003276"
                     /EC_number="1.4.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893107.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004355 - glutamate synthase (NADPH)
                     activity [Evidence IEA];
                     GO_process: GO:0006537 - glutamate biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NADPH-dependent glutamate synthase"
                     /protein_id="HFG9698966.1"
                     /translation="MDAKKVKVPVREQEPAVRATNFDEVCLGYNKEEAMAEANRCLAC
                     KKPKCVGGCPVGIDIPGFITKIKEDDIEGAAKVIAKSSSLPAVCGRVCPQESQCEGVC
                     ILGIKSDAVSIGKLERFVADWSKENDINLSDTEPKKNQKVAVIGSGPAGLACAGDLAK
                     KGYDVTIFEAMHEPGGVLTYGIPEFRLPKQAVVQPEIDNIRKLGVKIETNVIVGKTIT
                     VDELIEDEGFEAIFIGSGAGLPMFMNIPGENANGVFSANEFLTRVNLMKAYRDDYDTP
                     ISSGKKVAVVGGGNVAMDAARTALRLGSESYIVYRRSEKELPARAEEVHHAKEEGIIF
                     NTLTNPKEILVDENGYVKGMVCIRMELGEPDDSGRRRPIEIEGSEFVLDVDTVIMSLG
                     TSPNPLISSTTKSLDINKKRCLITDENGQTSKEGVFAGGDAVTGAATVISAMGAGKTA
                     AASIDEYLKAKVNA"
     gene            3152..5371
                     /locus_tag="ACGI5H_003277"
     CDS             3152..5371
                     /locus_tag="ACGI5H_003277"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429762.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EAL domain-containing protein"
                     /protein_id="HFG9698967.1"
                     /translation="MKKREKVFDGLVFKHILILLILLVLIDLTSTIIYASNSMEITSR
                     NMIEASKRELENYLEVNISLLKALSQDDRFSNGETSLIEKGKLLSPYQKEYNLFMIGI
                     TDTKGNASSTYRENVNSIKDKPSFEKAIKTKQVVVSDIEVSNVTGDKVFIIYVPIVKN
                     NEMIGTIFASFYFQDVNNLISRSNFDDSIKFLMIDKDYTIISHPNKKYVNDKSKMLDL
                     EGNIIGTTKSEILKNINKKCQGDFLSWDNWRLYNVKYTNIKWTNWTLVSKCNIFKNFK
                     NLIVNFMIKLYFYIVIFMILWKLSNAKLIEQLKKLAYYDSLSGIKNKEKFRKDSMYIL
                     KNYYQDNFYLVQLDVNKFKYINEMFGYAEGNKILIHISQVLNNNTNKYEICARMDNDH
                     FILLIACNTEDELLNRLSKINKEICNLNTTNSSKYKIVMSSGIYKITKKDDIKKIDLL
                     IDRANIAAKSKKEKYEHSYSFFNEDTRNRLYKEKRLEDNMNKALEKGEFIVYYQPKYS
                     LDDVNEIEGAEALIRWNSPEFGFISPIDFVPLFEKNGFIVNIDMFVFEEVCKTLNKWI
                     NKGYTPVPISVNMSRVHLYRDNFIENITDLISKYNISPEFIELELTESVVFDNLNILI
                     DIMKKIKEIGFLISMDDFGSGYSSLNLLKDLSFDILKLDRGFLIETTDTKRGKIIISK
                     IVEMAKAIDIKVICEGVETYEQVEFLKEIGCDKVQGYLFAKPMVLDEFEKHLNFKFD"
     gene            5518..6264
                     /locus_tag="ACGI5H_003278"
     CDS             5518..6264
                     /locus_tag="ACGI5H_003278"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014466367.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HFG9698968.1"
                     /translation="MNILSIRNISKTYCGNIPFKALDKVSLNIEKGEFVSVMGPSGSG
                     KSTLLNIISTVDRQSEGEVVLDGYDVSKLKGEKLAEFRRKQLGFVFQDFNLIDTLTVG
                     ENIMLPLTLEGASIKDMNIQTKSISKFLGIDKILDRKTYEISGGQAQRCAIARAIINK
                     PAILLADEPTGNLDSKSTDDVLKLFTRINKEQKVTTLMVTHEAYSASYSDRVIFIKDG
                     CIYTEIKKSESSNSFYSDILAVLSQIGGVR"
     gene            6264..8144
                     /locus_tag="ACGI5H_003279"
     CDS             6264..8144
                     /locus_tag="ACGI5H_003279"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861246.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HFG9698969.1"
                     /translation="MDFRKFAYNNIVKNFRAYLAYFLSSVFSIMIFFVFAVSMFHPII
                     TKSGMQSGSTAFMALMTSELIIFGFSLLFILYSLGNFLKYRLKDFGVLMIIGMSNRQL
                     KKLILIENLIIGFLAVMLGILLGLSISKLFLLYLSKLFYMNLTEFYFPVKAMLLTIVS
                     FMILFLITGPMSLKLLSKKSILELLVGTKKPKKEIKSSKLFGIIGVICLILGYAMILF
                     GNKLKINGGMYTTALLITLGIFLFFSQFTILILKYLKNKEKFYKNKVNMLLISNLIYK
                     LKDNTRLLFLITILLSATLVAFTTTSTLVSSQGEASKNNFPMVYSYFSEHNNEKEYEE
                     LQQIREAIKGYDYKELSFPVLKYNREVLLSVKNYNKLSKELGLDKISSKLEKYEGVII
                     PSSNSQEHINSLKQLKNYSIKNLNIEVKKSKNKIIFPTGLFSKVVVISDDLYNEVKGE
                     FSKINFHGFDYKNWQSSAQITENLKEKHFNLDREYNRSYFLTLPDMYLVELQQSKILQ
                     FMGVFIGVILFIAVFSFLYFRLYTDEIEDNVKYKKLSKIGLSFKNMNKIVSIEIGTLF
                     FIPYFIAIINSIISLLFLNQVLNNSFKLENLGILLLISSIYSLYFYLLKKIYTRKVWF
                     FD"
     gene            8263..9654
                     /locus_tag="ACGI5H_003280"
     CDS             8263..9654
                     /locus_tag="ACGI5H_003280"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420080.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0042910 - xenobiotic transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0006855 - xenobiotic transmembrane
                     transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MATE family efflux transporter"
                     /protein_id="HFG9698970.1"
                     /translation="MENQQLLGTERISKLLLKYSIPAIIGMLVNSLYNVVDRIFIGNI
                     PGVGPLAITGLGVTMPIMTIILAFGMLIGIGTTTTISIKLGQGKVEEARKLIGNAMTL
                     SVITGIIIMILGILFANKILTLFGASENTLIYAKSYINIILLGTVVNLLSFSLNHSIR
                     ADGSPKISAGIMIVGCLTNIVLDWILIFGFNLGIQGAAIATVTSQALTAILTIGYYIS
                     GKSNLRFSKSNLKLDKKLIKAVFAIGMSPFAMQLAASLVQVISNIALKTHGGDLAIGA
                     MATISSIAMVFLMPIFGINQGAQPIIGFNYGAEKYDRVKKAYLGSLVVATIILCMGMV
                     VVMLFPEAIIGIFNKDPELMNISVNGLRIYLLMLPIVGLSVTGTNFIQSIGKAKMAML
                     LSLLRQVILLIPAVLILPTFLGLQGVWTAQPVSDFIATVITGIVVFRELKRYTPKTEK
                     LNENERLNEITTE"
     gene            9761..10801
                     /locus_tag="ACGI5H_003281"
     CDS             9761..10801
                     /locus_tag="ACGI5H_003281"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436700.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fic family protein"
                     /protein_id="HFG9698971.1"
                     /translation="MEFTKKSKLKNMYVNMNVARMLSKINEYKGRQLLYKKQPKEILE
                     NLEKKSLVDCSESTYIGNQRDSSNFNLEKLISNEVTPRSREELSIVEYRDVVKTINSA
                     YESIPISSQTILELHGYLYKFSSTRGGSYKSDNDFIEHNLKPSEFISIDSSVNKVEKA
                     VEEICEAYNTLIEEDEIDILILISAFVLDFILIHPFKEGNIKMARVLILLLLNKNGYE
                     VGRYISLGKIFDDSSYEYYSNLNYLKASIGSEKADMNAWIEYFLETILTAYEKLDDSL
                     NISDKKRQTKTSRIEKIINSTLGYFTKEDIRDLCPDIPEPTINRVFNNLRKQDKIEVV
                     ARGRSAKWKKKY"
     gene            11290..11943
                     /locus_tag="ACGI5H_003282"
     CDS             11290..11943
                     /locus_tag="ACGI5H_003282"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728544.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent oxidoreductase"
                     /protein_id="HFG9698972.1"
                     /translation="MKKKLLYINVNSKPEDLSSSKTVARKFINKFMEKNKDFEVEEID
                     LYKEHIPRLEYQYFEKRNSIVSEENAKNLDDKDRKELTKIRNLCDQFVSASVYVIAAP
                     MWSLSFPAPLKEYIDCIIQDGKTISFEGNDKPQGILNDIDRSMVYIQSSGGHIPWVLK
                     PVMNKGLNYVESIMKFIGIKKFDELLVDGTGTSEEERQAAIEKAAEKIDGIIDGMKF"
     gene            12019..12228
                     /locus_tag="ACGI5H_003283"
     CDS             12019..12228
                     /locus_tag="ACGI5H_003283"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9698973.1"
                     /translation="MREEKSNEKYDCYWCNQENNFCVEIKDNIVMIDDGTGTLKQAVF
                     IGYKQIQINLNCSHCQNLNRIKLNL"
     gene            complement(12368..12934)
                     /locus_tag="ACGI5H_003284"
     CDS             complement(12368..12934)
                     /locus_tag="ACGI5H_003284"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728545.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1836 domain-containing protein"
                     /protein_id="HFG9698974.1"
                     /translation="MMNNELNTIILETLNNADITSNDIPSIDLYMDQIISLIDNKLSA
                     NKRFESDKILTKTMINNYSKEGLIKPVKGKKYTKEQILQMIIIYSMKNTLTIQEIKRI
                     LHGVYEKDNFSEKDLVSCYEKFMLIKENQRKNIPDFIESNFENISINPENKDDLLIAL
                     LSLTSMADQLKNISEKLVDRYFPDITKK"
     gene            13095..13748
                     /locus_tag="ACGI5H_003285"
     CDS             13095..13748
                     /locus_tag="ACGI5H_003285"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420089.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hemolysin III family protein"
                     /protein_id="HFG9698975.1"
                     /translation="MYQFFLKGRDPISSLTHFIGACLSLLATIILVFQSVTLQETSLL
                     MIVSVSVFGFSLIALYSASSYYHFLKGTPEQELFFRKVDHAMIYVLIAGSYTPICLNF
                     MEKKEGIIFVTAIWIVAFIGIIIKIFWMDAPRWLSTSIYLLMGWAIVFDINAFNSIPK
                     DCLRLLIMEGVSYSIGAIIYIIKKPNISPEFGFHEIFHIFIMIGSLFHFLAVLLYVL"
     gene            complement(13906..14082)
                     /locus_tag="ACGI5H_003286"
     CDS             complement(13906..14082)
                     /locus_tag="ACGI5H_003286"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420092.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9698976.1"
                     /translation="MYKYDDYVNLTNDLDLPVEIRNKCVRIVSVSENLEDIIIVHKFK
                     LYVVNEKYIKGIME"
BASE COUNT         5535 a         1392 c         2384 g         4815 t
ORIGIN      
        1 aaaaattcaa ataattaatg aatattgaaa attttagata tataataaaa taagagtata
       61 ttttatacaa tatgaaagct ggtattgcaa tagattaaag ccttatacac gtttagtttt
      121 taaagaaatt agtgttatta tgaaaaccta agttaattta ttaaataaat aattgaataa
      181 aaaaatttta ttatgtattt ataaaatttt tgttacaaat ttggcataat atagtatact
      241 ttaagtgtgt attaggttaa atctataaca aattagacgt atgatataga cttagtgttt
      301 attggcattt acaagaaatt tgttaatatc aactatttgt agtttgggca gttataatta
      361 ttataggggg gatgtccaat acaaaacaat caaccaagaa ctaatattat attataaaga
      421 gttatagttt tgtgtgttta tgtttttaat taaatttaaa gtgggaaaaa tatatttgtt
      481 agaatggaga atagcgagat gagtaataaa atagttagta agagacaatt aacagatagt
      541 atttatttaa tggaaataga ggcacctaga gttgcaaaat cttctcaacc aggtcaattt
      601 ataataatta aaaatgatga aaaaggagag aggattcctc ttacaatagc tgactatgat
      661 agagaaaaag gaacagtaac tattgtattc caaacagttg gtgcttcaac taaaaagtta
      721 gcaatgtttg aagaaaacga ttttgtaatg gattttgtag ggccattagg acaagcaagt
      781 gaatttatac atgaagatat agaagaatta agaaataaaa agatattatt tgtagctggt
      841 ggagttggtt ctgctccagt ttatccacaa gttaaatggt ttaaagagca tggattagat
      901 gtagatgtaa taattggtgc aagaactaaa gaattaatta tattagaaga tgatatgaaa
      961 aaagtagcta aaaatgtata tgtatcaaca gatgatggta catatggatt taatggaaga
     1021 gttacagacc tattaaaaga tttagttgat aatcaaggta aaaaatacga ccaagcaata
     1081 gtaattggac caatgataat gatgaaattt atgtgccaat taactaaaga actaaatata
     1141 cctactatag taagtttaaa tacaataatg atagatggaa caggtatgtg tggtggttgt
     1201 agagttagtg ttggaaatga aactaagttt gcatgtgtag atggtcctga atttgatggt
     1261 catttagttg attttgatca agcaatgaga agacagtcta tgtacaagac tcaagaggga
     1321 agagctatgc taaaacttga agaaggcgat agtcatcatc atagtaattg tggatgtgga
     1381 ggtaacaaat aatggatgct aaaaaagtaa aagtaccagt tagagaacaa gaacctgctg
     1441 tgagagcaac aaattttgat gaagtatgct tagggtataa taaagaagaa gctatggcag
     1501 aagctaatag atgtttagct tgtaaaaaac caaaatgtgt gggtggatgt ccagtaggaa
     1561 tcgacatacc agggtttata acaaaaatta aagaagatga tatagaaggt gctgctaaag
     1621 taatagctaa gagcagttca ttaccagctg tttgtggtag agtatgccca caagaaagtc
     1681 aatgtgaagg tgtatgtata cttggaataa aatcagatgc tgtatcaata ggtaaattag
     1741 aaagatttgt agcagattgg tcaaaagaaa atgacataaa tttatctgat acagagccta
     1801 agaaaaatca aaaagtagca gtaataggaa gtggtccagc gggtctagct tgtgctggtg
     1861 atttagctaa aaaaggctat gatgtaacaa tctttgaagc aatgcatgag ccaggtggag
     1921 ttttaactta cggaatacct gagtttagac ttccaaaaca agctgttgtt caacctgaaa
     1981 tagacaatat aagaaaatta ggtgtaaaaa tagaaactaa tgtaattgtt ggtaaaacaa
     2041 ttacagtaga tgaacttata gaagatgaag gatttgaagc tatattcata ggttcaggag
     2101 ctggtcttcc aatgtttatg aatataccag gggaaaatgc aaatggagta ttttctgcaa
     2161 atgagttttt aactagagta aacttaatga aggcttatag agatgattat gatacaccta
     2221 ttagttctgg taaaaaagtt gctgtagtag gtggtggaaa tgttgctatg gacgctgcta
     2281 gaactgcatt aagattaggt tcagaatcat atatagttta tagaagaagt gaaaaagagc
     2341 ttccagcaag agctgaagaa gttcatcatg caaaagaaga aggcattata tttaatacat
     2401 taacaaatcc taaggaaatt ttagtagatg aaaatggata tgttaaaggt atggtttgta
     2461 taagaatgga attaggagag ccagatgatt ctggaagaag aagacctata gaaatagaag
     2521 gttctgaatt tgtacttgat gtagacacag ttataatgtc acttggaaca agcccaaatc
     2581 cactaatatc ttctacaaca aagagtcttg atataaataa gaagagatgc ttaataacag
     2641 atgaaaatgg tcagacttct aaagagggtg tatttgcagg tggagatgct gttactggag
     2701 cagcaacagt aatatctgca atgggtgctg gtaaaacagc agcagcatca atagatgaat
     2761 atttaaaagc aaaagttaat gcttaatttg taaattaaag agagggtgtc tcaaaatgaa
     2821 ctttttagtt catgaggcac tctttttgta caaaatcaaa tatgttttaa tcatttcaac
     2881 aatgaaaatt tcattcctgt agaaagtcta acttttaggt cttagtacaa tctctatttt
     2941 gatgtagcca cttttttaga tggtttaata atttatcagt tattattgta atatttgata
     3001 ctaagtaaca taactttgtc taactatgat aaaatagtta tacaataaag gtcttgtaag
     3061 gagtgaataa tgtgtggcta ataaaatcag atttgtcaaa tctaacatta aataatagaa
     3121 aaataaattg tgtaattaat ggtattttaa tatgaaaaaa agagaaaaag tatttgatgg
     3181 gctagttttt aagcatatat taatcttatt aatactatta gttttgattg atttaacaag
     3241 taccatcata tatgcaagta actctatgga aattacttct agaaatatga ttgaggcatc
     3301 aaaaagagaa cttgaaaact atttagaagt aaacatatct ttattaaaag ctcttagtca
     3361 agatgataga ttttctaatg gtgaaacatc actaattgaa aagggaaaat tattaagtcc
     3421 atatcaaaag gaatataatc tttttatgat tggtataaca gatacaaaag gaaatgcttc
     3481 aagtacatat agggaaaatg ttaactcaat aaaagataag cctagttttg agaaagcaat
     3541 taaaacaaag caagtagtag tttcagatat tgaagtcagt aatgtaacag gtgacaaagt
     3601 atttatcata tatgtaccaa ttgtaaaaaa taatgagatg attgggacca tttttgcttc
     3661 tttttatttt caagatgtaa ataatttaat aagtagaagc aattttgatg attctattaa
     3721 atttctaatg atagataaag attatactat tatttctcat ccaaacaaaa aatatgtaaa
     3781 tgataaaagt aagatgcttg atttagaagg gaatattata ggaaccacta aaagtgaaat
     3841 cttaaaaaat ataaataaaa aatgtcaagg tgatttttta tcttgggata attggagatt
     3901 atataatgta aaatatacga acataaagtg gactaattgg actttagtat caaaatgtaa
     3961 tatatttaag aactttaaaa atctaatagt taattttatg ataaagttgt atttttatat
     4021 agtaatattt atgatattgt ggaaattaag taatgctaaa ttaatagaac aacttaaaaa
     4081 attggcttat tatgattctt taagtggaat aaaaaataaa gaaaagttta gaaaagattc
     4141 tatgtatatt ttaaagaatt attatcaaga taatttttac ttagtacaat tggatgtcaa
     4201 taaatttaaa tatataaatg agatgtttgg atatgctgaa gggaataaga tattaattca
     4261 tatatcacag gttttaaata ataatacaaa taaatatgaa atttgtgcta ggatggataa
     4321 tgaccatttt atattgttga ttgcttgtaa cactgaagat gaacttttaa atagattatc
     4381 taaaataaat aaagaaattt gtaacttaaa tactactaac tcatctaagt ataaaattgt
     4441 tatgtcaagt ggaatatata agattactaa aaaggatgat attaaaaaga ttgacttgtt
     4501 aattgataga gcaaatattg cagcaaaaag taaaaaggaa aaatatgaac attcatattc
     4561 attttttaat gaagatacaa gaaatcgatt gtacaaggaa aaacgattgg aagataatat
     4621 gaataaagct ttagaaaaag gtgaatttat agtatattat caacctaagt atagtttaga
     4681 tgatgtaaat gaaattgaag gagcagaagc cttgataaga tggaatagtc cagaatttgg
     4741 gtttatttca cctatagatt ttgtaccttt atttgaaaag aatggtttta ttgtaaatat
     4801 tgatatgttc gtgtttgaag aagtatgcaa aacattaaac aagtggataa ataaagggta
     4861 tactcctgta ccaatctctg taaatatgtc tagagttcat ttatataggg ataattttat
     4921 agaaaatata actgatttga taagtaaata caatatatct cctgagttta ttgaacttga
     4981 actaacagaa agtgttgtgt ttgataattt aaatatattg attgatataa tgaaaaagat
     5041 taaagagata ggattcctta tatcaatgga tgattttggt tcgggatatt catctttaaa
     5101 tctgttaaaa gacctttctt ttgatatttt aaaattagat agaggatttt taatcgaaac
     5161 aacagataca aaacgtggaa aaattattat ttctaagatt gtggaaatgg caaaagcgat
     5221 tgatattaaa gtaatctgtg agggcgtaga aacttatgaa caagtagagt tcttgaaaga
     5281 gataggttgt gataaggttc aaggatactt atttgctaaa cctatggtat tagatgaatt
     5341 tgaaaaacac ttaaacttta aatttgatta atcattaata attattagac tataatatac
     5401 cctaacaact tacttacaaa tatgtaagtt aattgttagg gtatttttat ggttaaagta
     5461 gtatattcac gatattatgg tattgtagta aaaataaaaa attatggaga atataaaatg
     5521 aacatattga gtattagaaa tatatcaaaa acatattgcg gaaatattcc atttaaagca
     5581 ttagataagg ttagtctaaa tatagaaaag ggagaatttg tgtctgttat gggaccatct
     5641 ggaagtggta aatctactct tttaaatata atatctacag ttgatagaca gagtgaaggt
     5701 gaggttgtat tagatggata tgatgtaagt aaattgaaag gagaaaaact tgctgaattt
     5761 agaaggaaac aacttggttt tgtatttcag gattttaatt tgattgacac tttaactgtt
     5821 ggcgaaaata ttatgttgcc acttacacta gagggggcaa gtatcaaaga tatgaatata
     5881 caaactaaaa gtatatctaa atttttagga atagataaaa ttttagatag aaaaacctat
     5941 gaaatttcag gaggtcaagc tcaaaggtgt gctattgcta gagctattat aaataaacct
     6001 gccatacttc ttgcagatga gccaactgga aatcttgatt caaaatctac tgatgatgtt
     6061 ttgaaattat ttactaggat aaacaaagaa caaaaggtaa caacacttat ggtaactcat
     6121 gaagcatata gtgcaagtta ttcagataga gtaattttta taaaagatgg ttgtatatat
     6181 acagaaataa aaaaatctga aagcagtaat tctttctatt ctgatatact agctgttttg
     6241 tctcaaatag gaggtgtaag atagtggatt ttagaaagtt tgcttataat aatatagtta
     6301 aaaatttcag ggcatattta gcatattttt taagttctgt tttttctata atgatatttt
     6361 ttgtttttgc agtgtctatg ttccatccaa ttataacaaa atctggaatg cagagtggtt
     6421 ctactgcatt tatggctctt atgacttcag aattaataat attcggtttt agtctacttt
     6481 ttatattgta ctctttagga aatttcttga aatatagatt gaaagatttt ggagtattga
     6541 tgataattgg aatgagtaac agacaactga aaaaattgat attaattgaa aatttgataa
     6601 taggattttt agcagtgatg ttaggaatat tacttggttt atcaatttca aaattgtttt
     6661 tattgtattt aagcaaactg ttttatatga atttaactga attttatttt ccagtaaaag
     6721 caatgctatt gactattgta tcatttatga ttttattttt gataacagga ccaatgagct
     6781 taaaattatt gagtaaaaag agcattttag agcttttagt aggtacaaaa aagcctaaaa
     6841 aagagataaa atcttcaaag ctatttggaa taattggtgt aatatgtctt atattaggat
     6901 atgctatgat actatttggc aataagttaa aaataaatgg aggtatgtat acaacagcac
     6961 tattaattac tttggggata tttttatttt tttctcaatt tactattttg atattaaagt
     7021 atttaaaaaa taaagaaaaa ttttataaga acaaagtaaa tatgttactt ataagtaatt
     7081 tgatatataa attaaaggat aatacacgat tgttattttt aataacaata cttttatcgg
     7141 ctactttagt agcatttaca acaacttcaa cacttgtaag ttctcaagga gaagcttcta
     7201 aaaataattt tccaatggtt tactcatatt tttcagagca taataatgaa aaagaatatg
     7261 aagaactaca acaaattaga gaagcaatca aaggatatga ttataaggag ttaagttttc
     7321 ctgtacttaa atataatagg gaagtcttac taagtgtaaa gaattataac aaattatcaa
     7381 aggaattggg attagataaa attagttcaa agttagaaaa atatgaaggg gttataattc
     7441 ctagtagcaa ttcacaagaa catataaatt ctttaaaaca attaaaaaat tatagtataa
     7501 aaaatttaaa tatagaagta aaaaaatcaa aaaataaaat aatttttcct acaggactgt
     7561 ttagtaaagt tgtagttata agtgatgact tatacaatga agtaaaaggt gaattttcaa
     7621 aaattaattt tcatggattt gattataaaa actggcaaag cagtgcacag ataactgaaa
     7681 atttaaaaga aaaacatttt aatttggata gagaatataa caggtcatat tttttaacat
     7741 taccagatat gtatttagta gagttacaac aaagtaaaat tcttcaattt atgggtgttt
     7801 ttataggagt gatattattt atagcagttt ttagtttttt atactttaga ttatatacag
     7861 acgagataga agataatgta aagtacaaaa aactatcaaa aataggtcta tcttttaaaa
     7921 atatgaataa gattgttagt atagagatag gtacattgtt ttttataccg tattttatag
     7981 caattataaa tagcataatt tctttactgt ttttaaatca agtattaaat aatagtttta
     8041 agttagaaaa tttgggtata ttactactga tatcatctat atattcactt tatttttact
     8101 tattaaaaaa aatttatact agaaaagttt ggttttttga ttaaagtggt atataataga
     8161 tatataaatt aatatttaaa aagtagttaa tattagggga gggcatttgc acctcccttg
     8221 taatatgtgg aaaattgaat attagaagaa ggaggagact tgatggaaaa tcaacaatta
     8281 ttaggaacag aacgaattag taaattacta ctaaaatatt ctataccagc tataataggt
     8341 atgttggtaa atagtttata taatgtagta gatagaattt ttattggaaa tataccaggg
     8401 gttggaccac ttgcaataac aggtcttggt gtaacaatgc caataatgac aataatactt
     8461 gcatttggga tgttgatagg tataggaact actactacca tatcaataaa acttgggcaa
     8521 ggtaaagtag aagaggcaag aaaacttata ggaaatgcaa tgacgttatc tgtaataaca
     8581 ggaattatca taatgatact tggaatatta tttgcaaata aaatacttac attgtttgga
     8641 gcaagtgaaa atactttaat atatgcaaaa tcatatatca atattatatt attaggtaca
     8701 gtagtaaatc ttctttcctt ttctttaaac cactcaataa gagctgatgg tagtcctaaa
     8761 atttcagcag gaataatgat agtaggatgt ttaactaata tagttttaga ctggatatta
     8821 atatttggat tcaatttggg aatacaagga gctgcaattg ctacagtaac ttctcaggct
     8881 cttacagcta ttttaactat agggtattat ataagtggaa aatcaaactt acgattcagt
     8941 aaatctaatc taaaattaga taaaaagcta ataaaagcag tgtttgcaat aggtatgtcg
     9001 ccatttgcta tgcaacttgc agcaagttta gttcaagtaa tatcaaatat tgcacttaaa
     9061 actcatggtg gagatttagc tataggggct atggctacta tttcttctat tgcaatggta
     9121 tttttgatgc ctatctttgg aataaatcaa ggagcgcaac ctattatagg tttcaattat
     9181 ggagctgaaa aatatgatag ggttaaaaaa gcatatttag gttcattagt agtagctact
     9241 ataattttat gtatgggtat ggtagtagtt atgcttttcc cagaagctat tataggtata
     9301 tttaataaag accctgaact tatgaatata tctgttaatg gattaagaat atacttactt
     9361 atgttgccaa ttgtaggctt atcagttaca ggaacaaact ttatacaatc tataggaaaa
     9421 gcaaaaatgg ctatgttatt gagcctttta agacaagtaa ttttattgat accagcagta
     9481 ttaattcttc ctacattctt aggtttacag ggtgtatgga cagctcaacc agtgtctgat
     9541 tttatagcta cagtaattac aggtatagtt gtatttagag aattaaaaag atatactcct
     9601 aaaactgaaa aattaaatga aaatgaaaga ctaaacgaga taactactga gtaaaaatat
     9661 aaattcagat aattgagcaa gaaattgcaa aaaatacgat tatatgataa aataaaaccg
     9721 ctgtcaagga taagagaaat tctaattatg gagtgatttt atggaattta caaagaaaag
     9781 caaattaaaa aatatgtatg taaacatgaa tgtagctaga atgttgtcta agataaatga
     9841 gtataagggt agacaactgc tttacaaaaa acaaccaaaa gaaattttag aaaacttaga
     9901 aaaaaaatct ttagtagatt gttctgaatc tacatacatt ggaaatcaaa gagatagtag
     9961 taattttaat ctagaaaagt tgataagtaa tgaagttaca cctagaagta gagaggaatt
    10021 gagtattgtt gaatacagag atgtggtaaa aactattaac agtgcttatg agagtattcc
    10081 catcagttca caaacgattc ttgagcttca tggatactta tataaatttt catctactag
    10141 aggaggaagt tataagtcag ataatgattt tattgaacac aatttaaaac ctagcgaatt
    10201 tataagtatt gattcaagtg tcaataaagt tgaaaaagct gtagaagaaa tatgtgaagc
    10261 ttataataca ttgatagagg aagatgaaat tgatatatta atattaattt ctgcatttgt
    10321 gttagatttc atattgatac atccattcaa agaaggtaat ataaaaatgg cgagagtact
    10381 tatcctattg ttactaaata aaaatgggta tgaagttgga agatatataa gtttaggaaa
    10441 gatatttgat gatagttcat atgaatatta tagtaattta aattatttga aagcctcaat
    10501 aggtagtgaa aaagcagata tgaatgcatg gattgagtat tttttagaga cgatattaac
    10561 tgcatatgag aagctggatg atagtttaaa tatatctgat aagaaaagac aaacaaaaac
    10621 tagtagaata gagaaaataa taaattctac ccttggatat tttacaaaag aagatataag
    10681 agatttatgt cctgacattc cagaacctac tataaataga gtttttaata atctaagaaa
    10741 acaagataag atagaagttg ttgcaagagg aagaagtgca aaatggaaga aaaaatatta
    10801 aaaaatgttt agataactaa aatggtatag tgttttacac tataccattt ttaatgtcat
    10861 tagcatgagc aataatttaa caacttaagc aatatcaatt ttatttattg attatttttg
    10921 aactgaaaaa tggcgttata tggtatacct cagtggtaat taattttgga tgagaagata
    10981 taatattaca gaatatatta ggagtatatg tagaaaaaat ataataaaag tgtgaggctt
    11041 agtaattaac aaattatgtg gcttcacact tttttataaa ataaagatac ttagcagaag
    11101 aatattttag ttgatatgtt tataagatgg tacttgtttg ggtaaaagta taaatagtaa
    11161 aaaagtagaa gtaatgtgta taaaaacgta agttacattc tgtaataata gttattttat
    11221 aattcaacaa aagaatagaa tgggtatatt tgtgaaataa taatataaaa taatcttagg
    11281 agtgagctta tgaagaaaaa attattatat ataaatgtaa attcaaaacc tgaagactta
    11341 tcttcaagta aaactgtagc aagaaaattt ataaataaat ttatggaaaa aaataaagat
    11401 tttgaggttg aagagataga cctttataaa gaacatatac caagacttga gtatcagtac
    11461 tttgaaaaaa gaaatagcat agttagtgaa gaaaatgcta aaaatttaga cgataaggat
    11521 agaaaagaac ttacaaagat tagaaatctt tgtgaccaat ttgtgagtgc aagtgtatat
    11581 gtaatagcag cacctatgtg gagtttatct tttccagcac cacttaaaga gtatatagat
    11641 tgtataattc aagatggaaa aactatatct tttgaaggca atgataaacc acaaggaatt
    11701 ttaaatgata ttgatagaag tatggtatat atacaatctt ctggtggaca cataccatgg
    11761 gtgttgaagc cagttatgaa taaagggtta aattatgtgg aaagtattat gaaatttata
    11821 ggaattaaaa aatttgatga attgttagta gatggaactg gaactagtga agaagaaaga
    11881 caagctgcta tagaaaaagc agctgaaaaa atagatggta taatagatgg gatgaaattt
    11941 taattataat attttattaa aaatataaag gaaaaacctc ttttaatgta gaaacttata
    12001 ttgaaggagg cgagaatcat gcgagaagaa aaaagtaatg aaaagtatga ttgttattgg
    12061 tgtaatcaag agaataattt ctgtgtagaa ataaaagata atatagtcat gatagatgat
    12121 ggcactggta cgttaaaaca agccgttttc atagggtata aacaaatcca aattaattta
    12181 aactgttcac attgtcaaaa cttgaataga ataaaattaa atttgtagaa ttttaaaatg
    12241 gaaattattg aaggaattaa aaatagaaag tgttaatatt tagactgaaa attatatttt
    12301 atacaataaa agtttattta aataacattg tattttaata tttattttca gtcttacttt
    12361 attaaaatta ttttttggtt atgtctggaa aatatctgtc tactaatttt tctgaaatat
    12421 tttttaattg gtcagccatt gaagtcagac ttaataaggc tatcaataaa tcatctttat
    12481 tttctggatt tatactaata ttttcaaaat tagactctat aaagtccggt atattctttc
    12541 tttgattttc ttttattaac atgaattttt cgtaacatga aactaaatct ttttcactga
    12601 aattatcctt ttcatacaca ccatgtaaga ttcttttaat ttcttgtatt gtaagtgtat
    12661 ttttcataga ataaataatt atcatctgta aaatttgttc tttagtatac ttttttccct
    12721 taactggttt gattaatccc tctttgctgt aattatttat catggtttta gtaagaattt
    12781 tatcactttc aaatctttta ttggcagaaa gcttattgtc aattagagaa ataatttgat
    12841 ccatatataa gtcaatagat ggaatatcgt ttgaagttat atctgcatta tttagtgttt
    12901 ctagtattat agtattaagt tcattattca tcatatgtta cctccataat atatataata
    12961 cactaaatta gaaagtaaaa caatattaag gcttgtaaaa aaaacataaa gtggtataat
    13021 taaatatata atatagtaat ggaaactata tttgtgaatc tgatttttaa aatacataat
    13081 tgtaggagga cgaaatgtat caattttttt taaagggtag agacccaata agcagtttaa
    13141 ctcattttat aggtgcttgt ttatctcttt tagcaactat aattttagtt tttcaatctg
    13201 ttacattaca ggaaacttct ctcttgatga tagtatctgt atcggtattt ggattttcac
    13261 taattgcttt atatagcgca agttcgtatt atcatttttt aaaggggaca ccagaacaag
    13321 aattgttttt tagaaaagta gaccatgcaa tgatttacgt attgattgct ggctcttata
    13381 caccaatatg tctgaatttt atggaaaaaa aagaaggcat aatatttgtt acagcaatat
    13441 ggatagttgc atttattggt ataataataa aaatattttg gatggatgca cctagatggt
    13501 tatctaccag tatatattta cttatggggt gggcaattgt ttttgatata aatgcattca
    13561 attcaattcc taaggattgc cttagactat taattatgga aggtgtatct tactctatag
    13621 gtgcaattat ttatataatt aaaaagccta atataagtcc tgagtttgga tttcatgaaa
    13681 tatttcatat ttttattatg ataggttctt tatttcactt tttagcagtt ttattgtatg
    13741 ttttatagtt ttaaaagatt tgattaattg atactaaaat tctacaatga ataaaatgga
    13801 actgccttat atagattata tcttcgacaa taagacagtt ccttattata aatattaaat
    13861 tctacttata ataaaatttt gataaaaata gtccattcaa aatgcctatt ccataattcc
    13921 tttaatgtac ttttcattta cgacatatag tttgaattta tgtactataa ttatatcctc
    13981 taaattctct gaaacactaa caattctgac acatttgttt ctaatttcta caggtaaatc
    14041 taaatcattt gttaaattca catagtcatc atatttatac ataaaatcat ccctttacat
    14101 taagatatac ttattatact atattt
//
LOCUS       DAYAOO010000099        14050 bp    DNA     linear   BCT 12-OCT-2024
DEFINITION  TPA_asm: Clostridioides difficile isolate ST8-SSI-h139-18
            SAMN40601845-rid21577343.denovo.100, whole genome shotgun sequence.
ACCESSION   DAYAOO010000099 DAYAOO010000000
VERSION     DAYAOO010000099.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN40601845
            Sequence Read Archive: SRR28438827
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 14050)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 14050)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-MAY-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-MAY-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002157583.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002157583.1
            Genome Coverage       :: 163x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/11/2024 16:19:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 4,038
            CDSs (total)                      :: 3,963
            Genes (coding)                    :: 3,930
            CDSs (with protein)               :: 3,930
            Genes (RNA)                       :: 75
            rRNAs                             :: 6, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 60
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 33
            CDSs (without protein)            :: 33
            Pseudo Genes (ambiguous residues) :: 0 of 33
            Pseudo Genes (frameshifted)       :: 7 of 33
            Pseudo Genes (incomplete)         :: 25 of 33
            Pseudo Genes (internal stop)      :: 11 of 33
            Pseudo Genes (multiple problems)  :: 8 of 33
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..14050
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN40601845-rid21577343.denovo.100"
                     /isolate="ST8-SSI-h139-18"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Denmark"
                     /collection_date="2018"
                     /collected_by="Statens Serum Institute"
     gene            complement(172..798)
                     /locus_tag="ACGI5H_003287"
     CDS             complement(172..798)
                     /locus_tag="ACGI5H_003287"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GyrI-like domain-containing protein"
                     /protein_id="HFG9698977.1"
                     /translation="MKYEWRKRDKELYLPKKNPVIVEIPEQKFIMLKGSGDPNSKEFT
                     EAIGVLYSLAYAIKTMPKKGIVPEGYFDYTVFPLEGIWDKGEKSKGLDVLIKEDLIYT
                     IMIRQPDFVTQDLLDKATDIVKKKKPHNLLEKVRFGSINEGLCVQMLHIGSYDNEPES
                     FDIMNEFCKKNKLIRKSYTHREIYISDARKVSPESLKTVLRFEVEREV"
     gene            complement(874..1845)
                     /gene="nrdF"
                     /locus_tag="ACGI5H_003288"
     CDS             complement(874..1845)
                     /gene="nrdF"
                     /locus_tag="ACGI5H_003288"
                     /EC_number="1.17.4.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728983.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005971 - ribonucleoside-diphosphate
                     reductase complex [Evidence IEA];
                     GO_function: GO:0004748 - ribonucleoside-diphosphate
                     reductase activity, thioredoxin disulfide as acceptor
                     [Evidence IEA];
                     GO_process: GO:0009263 - deoxyribonucleotide biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="class 1b ribonucleoside-diphosphate reductase
                     subunit beta"
                     /protein_id="HFG9698978.1"
                     /translation="MTFNLHKIHNAVNWNREEDGFTQAFWEQNVKQFWLPEEISVSKD
                     IKVWNELSNKEKELYKKVLGGLTLLDTKQGNNGIPSMMSLTENLQRKAVLSFMGTMEE
                     IHAKSYSSIFMTLLSNLEIDELFEWIETEPTLQRKADLVLAQYENTTNQEGLYLSMVT
                     SVFLESFLFYSGFFYPLYLSGQGKMVASGEIISLILRDESLHGKYIGLLAQEIYDSFD
                     KMDKEMLEEKMYSILYSLMENEIEYTNVIYRESGLEKEVVNFLKYNANRALENLGFEK
                     LYTVDAINPIVLNGLSTETKTHDFFSTKGNGYQKGVYEELEDEDFII"
     gene            complement(1858..3957)
                     /gene="nrdE"
                     /locus_tag="ACGI5H_003289"
     CDS             complement(1858..3957)
                     /gene="nrdE"
                     /locus_tag="ACGI5H_003289"
                     /EC_number="1.17.4.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422595.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004748 - ribonucleoside-diphosphate
                     reductase activity, thioredoxin disulfide as acceptor
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006260 - DNA replication [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="class 1b ribonucleoside-diphosphate reductase
                     subunit alpha"
                     /protein_id="HFG9698979.1"
                     /translation="MNWIELNNQVIIKNEQGKYQLEKDKEALSSYIEEFIQPKLRKFN
                     NLEERLKYLIDEGYYSKEVINQYSIDVIKNIYDMIDKHKFEFQSYMSANKFYQNYALK
                     SNDGKEILETYNDKVLIVALTLGNGDKDLALNLADKIVKQEFQPATPTFLNAGRKRAG
                     EMVSCFLLSVEDSTEGISYAISSSNHLSKIGGGVALNLSKLRASGESIKDIEGAAGGV
                     VGVAKMLEQSFSYFNQMGARQGSGAVYLTVFHPDFELLMDTKKINADEKIRLATLSLG
                     AIIPDKFMELAEKNEVAYAFYPHTVYKKYGVSLDEIEMDKWYDKLVNDSDIRKKEINP
                     RQMLTKIAQMQQESGYPYVVYIDTANREHTLKDVGIIKMSNLCCEIFQYQTPSEIEGY
                     GGKNEWGQDISCNLGSLNIANVMDNKTIESTVETAIRALSFVADSTDIKPVPTVSNSN
                     SKSHSIGLGAMNLHGYLVRENILYTSDDAIDFSNVFFAMVRYYSIKASMKIAIERNQT
                     FEGFDKSEYVKGRNSKVLSKYYEQSYLPKSEKVRALFEGIYIPTKEDWTKLLDEVKEK
                     GIYNAYLMAVAPTQSISYVQNATSSIMPITEPVEVRTYGDSTTIYPMPFLTNDNMLYY
                     QSAYRMDMRKVIDLVATVQNHVDQGISTTLFVTDEKTTRDIARHYIYAYKKGLKSLYY
                     TRTKMTRDTHECLVCSV"
     gene            4435..5160
                     /locus_tag="ACGI5H_003290"
     CDS             4435..5160
                     /locus_tag="ACGI5H_003290"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pentapeptide repeat-containing protein"
                     /protein_id="HFG9698980.1"
                     /translation="MKTISKQELEKTLEKHYLWLKNNNAGEKADLKELRLENMDLRGY
                     CLSNIDFSWSDLINLNLEKADLENSIFNNSYLSDCSLKNSILKNADLSGASFRFCDLS
                     NSDIRGANLENSNLEYATLNGVISDESTRFFKLYCPETGAFIGYKKCFNFRMVQLLIP
                     SDAKRVSATSNACRCDKAKVLSITSVDGKESFKSARAYADENFIYRVGETIVAEDFNE
                     NRWKESTTGIHFFLTREEAIGYL"
     gene            complement(5288..6484)
                     /locus_tag="ACGI5H_003291"
     CDS             complement(5288..6484)
                     /locus_tag="ACGI5H_003291"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429077.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HFG9698981.1"
                     /translation="MLKTNNLSVGYNNKVVISNINVEVKNGEILCLLGSNGAGKTTLL
                     RSLSKLISPIKGEIYLNGVNINCISRKALSKKMALVLTNRLLGDLMTVQDIVNIGRYP
                     YTGFFGSLSKKDLIMVDEALESVDALHLKKRYFDELSDGEKQKVLVARALVQEPEIII
                     LDEPTTHLDIKHRLELINILKKLSKEKSISVILSLHEIDIALKSCDKVALIKNNKVIA
                     YGQPEDVVDEDIINSLYELDDKNFNSLLGSVEISNKSKNEVFIIGGGGKATPIYRAFT
                     KKGIGLYSGIIHENDIDYEIGRTMGIKMFTENPFEPISDESFDLAIRNLNDSKIIIDT
                     GFSVGETNKRNIDIIKEALKLDKKVYSFRNRDESKKYYDSLDSKIEHIDKVSQIINSA
                     DINNLL"
     gene            complement(6487..7512)
                     /locus_tag="ACGI5H_003292"
     CDS             complement(6487..7512)
                     /locus_tag="ACGI5H_003292"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429076.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="FecCD family ABC transporter permease"
                     /protein_id="HFG9698982.1"
                     /translation="MDFINKMRIRNTTIFIVLIISMILTFLVCVAFGSVKIEFKEVID
                     VVLRGMDNTEHYKIIYNIRIPRVLATMVGGACLAVSGILLQIFFKNPIVEPYILGVSS
                     GSTLSVALMILGGYTLGFESVNSMSIFVAAFIGALIVMSIVILFANKVKNITTLLIIG
                     IMTGYVCSGITNVLQSFANSDKLKEFTMWSMGSFSGFTWEKVEILIIVGILGLLMTVF
                     IIKPLNAFLLGEEYAKSIGINIRFFRVLIVFISSILAAIVSAFAGPIGFIGLAVPQIS
                     KMIFKTSDNRVLIPVVIFLGSIVTALCDLISRVILSPVELPISTITSLLGAPIVVMLL
                     VKRKDRA"
     gene            complement(7584..8714)
                     /locus_tag="ACGI5H_003293"
     CDS             complement(7584..8714)
                     /locus_tag="ACGI5H_003293"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728987.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HFG9698983.1"
                     /translation="MKFKSNVLKQFFLIAMVIFMVGGLIGCSKSDKENKQASTGKKLE
                     LKYASGFSVEDLEDGIKKVTDGDNRELILIPKKIKIPEKYKNANIVRTPVDNVLIAST
                     TQACSLRTIDELDSIKAVTTQEQYWTIKEIKDLMKDGKIHYVGSNLAPDYEKIVDLNP
                     DLTIVSSGLSEADTKFIDKLKELGLNYVVDNEYKEQNPFGRMEWTSLIAAFYDKEDMA
                     TSELNKTVQKVEEVSKKIKNKAKPKVVWASVYEGSAYIAPKDSYVDNMIKMAGGINAC
                     ASIDSNEGRVSIEQLHEVAKDADIFVYSSSSDYAPNLDSIKSSAPVLADLDVVKNGNL
                     WVFAPDYYQSVDKTDELIVDLVEMFHPGTTGEKIKHYINYDK"
     regulatory      complement(8942..9123)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00174"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="cobalamin riboswitch; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="adenosylcobalamin"
                     /db_xref="RFAM:RF00174"
     gene            complement(9176..10069)
                     /locus_tag="ACGI5H_003294"
     CDS             complement(9176..10069)
                     /locus_tag="ACGI5H_003294"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891302.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrodipicolinate synthase family protein"
                     /protein_id="HFG9698984.1"
                     /translation="MKAEFLTPVVTIFDEEGNLDKEGNKKVYDHLIDGGVDGLVIMGS
                     TGEFFNMSMDMQKELIDLVTSHVNKRVKVFIGTSRMCINESIELSNYAHNSGADGVMI
                     ISPYYFSLDDDSIELFYSEIAKNTEAEIYLYNYPDRTGYDLSPELTLRLARKHKNIVG
                     YKDTVTLMGHTRDLINTMKIEFPEFKVYSGYDENFIHNLMSGGAGCIGGLSNLIPEVC
                     SKWAEAYNNRDMEKVIEIQKYINKAMDFYLITNPFIPAMKKAMNIRGLQISDYMTAPF
                     VKPNEKQVCEIKKLMNELNIC"
     gene            complement(10149..11051)
                     /locus_tag="ACGI5H_003295"
     CDS             complement(10149..11051)
                     /locus_tag="ACGI5H_003295"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429073.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003824 - catalytic activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="fumarylacetoacetate hydrolase family protein"
                     /protein_id="HFG9698985.1"
                     /translation="MKFVSFTEGENECKRTGVFSKDELFIIDVNSLNLSRNFKDLNEL
                     IQNVSSEDIIKLKTIINESTFYNYDVFKRERCTVHVPIEKPIHDILCVGVNYKDHLEE
                     TQTHFDDSFEEPQKTVYFTKRVTKAIGPEDEIDGHFEINNQLDYEVELGVVIGKTGVN
                     IRKEEVEDYIFGYTVINDISARKLQKEHVQWFRGKGLDTFTSLGPCILHKSAVPFPIK
                     LKVCSRVNGEERQSSNTGLFISDVSDIVSELSKGMTLEAGDIIATGTPSGVGMGFSPP
                     RYMSSGDVVECEIESIGILKNYIK"
     gene            complement(11101..12261)
                     /locus_tag="ACGI5H_003296"
     CDS             complement(11101..12261)
                     /locus_tag="ACGI5H_003296"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439842.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UxaA family hydrolase"
                     /protein_id="HFG9698986.1"
                     /translation="MKFYGYKRPDGRVGIRNHILILPTSVCASDTTRIIASQVQGAVT
                     FNNQNGCSQVHSDQQLTMDVMAGYAANPNVYGVIVVSLGCENCQNDLVVDAIKERTNK
                     PIKTLVIQEEHGTLKTIEKAVRYAREMAQEASLLRKEEFPISELILGTECGGSDPTSG
                     LAANPLIGELSDKLVDLGATSILSETTEFIGAEHILARRAVNEEVKEKILHIVHRYEN
                     SLKLVGEEVREGNPSPGNIAGGLTSLEEKSLGCIHKGGHRQISEVYDYAKQIDKKGLV
                     IMDTPGNDASSVAGMVAGGAQIVVFSTGRGTPSGNPIAPVIKITGNKITFANMEDNLD
                     FDASPVIYGPQTMEELTDDLLNMVVDVANGKQSKAESLGYTEMAIARVCNYV"
     gene            complement(12417..12722)
                     /locus_tag="ACGI5H_003297"
     CDS             complement(12417..12722)
                     /locus_tag="ACGI5H_003297"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422587.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UxaA family hydrolase"
                     /protein_id="HFG9698987.1"
                     /translation="MINAVIIDEKDNVAVAIEAIAKGSEISFKLKDKTVKTITALDDI
                     TIYHKLAIKDMAQGDKVTKYGEHIGEANQEIKSGQHVHIHNVRSVREDLDKQVMTNI"
     gene            complement(12820..13794)
                     /locus_tag="ACGI5H_003298"
     CDS             complement(12820..13794)
                     /locus_tag="ACGI5H_003298"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422586.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-keto-3-deoxygluconate permease"
                     /protein_id="HFG9698988.1"
                     /translation="MIMDFIKKIPAGMMIVPMFIAAFINTFCPDIVQIGSFTTAVFSS
                     VGSATIIGVQLVCLGTQLQFREMPKVLKRGGILLGSKFAIGALIGILIGKLFGMDGVL
                     GLTTLAVISAVTNSNGSIYLSLMTSYGDETDCATMSLLTLNDGPFFTLIALGTSGLAN
                     VPLLSLLAAIVPILVGMIIGNFDKKMKEFLEPGCNLLVPFVGFALGSSINLASILKGG
                     LSGVLLGLISVFVGGIFIVFCDKFIGKRPGYAGWAVATTAGNAIAVPAAVALVDPSWQ
                     PYVATATTQVAAAVVVTAILVPLITSWWAKKYGCPKFPKQNEDGTITA"
BASE COUNT         4494 a         2572 c         1530 g         5454 t
ORIGIN      
        1 taatacttat ataattagta ttattattta atagcaacag ttattcacac taataaaagt
       61 agaaagtttt taaaatatta tgaaacatca aatttaattt taaaattgca tcaaaaaatg
      121 aagtctcaac agacttcact ttttataact cttataaatt attcaaaata tttatacttc
      181 cctttctact tcaaaacgta aaaccgtctt caatgattca ggcgatactt ttctagcatc
      241 acttatataa atttcacgat gtgtgtaaga ttttcttata agtttatttt ttttgcaaaa
      301 ttcgttcata atgtcaaagc tttctggttc attatcatat gaacctatat gaagcatttg
      361 aacacatagc ccttcattaa tagacccaaa tctaactttt tcaagaagat tatgaggttt
      421 tttcttcttt actatatcag tagctttatc caacaggtct tgtgtaacaa aatctggctg
      481 acgtatcatt atagtgtaaa ttaaatcttc tttaataagt acatctaagc ctttactttt
      541 ttctccctta tcccatatac cttctaaagg aaaaaccgta tagtcaaaat acccttctgg
      601 tacaattcct tttttaggca tggtttttat tgcatatgcc aaagaataaa gtactcctat
      661 tgcttcagta aattctttag aatttgggtc tccactccct tttaacatga taaatttctg
      721 ttctggtatt tcaactatta caggattctt tttaggtaaa tataactctt tatctctttt
      781 tctccattca tatttcataa aaatacctcc atatatattt tatacattga tattatcacg
      841 ctaaaagtga caacagtgtg tcataattat aaattatatt ataaaatctt catcctctaa
      901 ttcctcatac actccttttt ggtatccatt acccttagtt gaaaaaaaat catgtgtttt
      961 ggtttcagtg ctaagaccat ttaatacaat tggatttata gcatctacag tatatagctt
     1021 ctcaaaccct agattttcta aagctctatt cgcattgtat tttaaaaagt tcacaacctc
     1081 tttttcaagc ccactttctc tgtatataac atttgtatac tctatctcat tctccataag
     1141 gctataaagt atagaataca tcttctcttc taacatctcc ttatccattt tatcaaatga
     1201 atcgtatatt tcttgtgcta gcaatcctat atacttacca tgtaaagact catctctaag
     1261 aataagcgat attatttctc cactagctac catctttcct tgaccagata gatacaatgg
     1321 ataaaagaat cctgaataaa acaagaaact ctctaaaaat acacttgtaa ccattgatag
     1381 gtataatccc tcttgatttg tagtattttc gtattgagct aaaactaaat cagcctttct
     1441 ttgtaatgtt ggttctgttt ctatccattc aaataattca tctatttcta aattagaaag
     1501 tagagtcata aatatagaag aataactttt tgcatgtatt tcttccatag tccccataaa
     1561 agacaagaca gcttttcttt gtaggttttc tgttaaactc atcatagatg gtattccatt
     1621 attcccctgt tttgtatcca gtaatgttaa accacccaat acttttttat ataattcctt
     1681 ttctttatta cttagttcat tccatacctt tatgtcttta gaaacagata tttcttcagg
     1741 aagccaaaat tgttttacat tttgttccca aaaagcttgt gtaaatccat cttcttctct
     1801 attccagtta actgcattat gtattttatg taaattaaat gtcatatatt tctctcccta
     1861 tactgaacac actagacact catgagtatc tcttgtcatc tttgttcttg tgtaatataa
     1921 acttttcaaa ccttttttat aggcatatat gtaatgtcta gctatatctc tagttgtctt
     1981 ttcatctgta acaaacagtg ttgttgatat accttggtca acatggtttt gaactgttgc
     2041 cactaaatct atgacctttc tcatatccat cctgtatgct gattgataat acaacatatt
     2101 atcatttgtt aaaaatggca ttggatatat tgtagtagag tctccatatg ttcttacttc
     2161 tactggctca gtaattggca ttatacttga tgtagcattt tgaacataac taatgctttg
     2221 agttggtgct actgccatta aatatgcatt atatatccct ttttctttta cctcatccaa
     2281 taattttgtc cagtcttctt ttgttggtat ataaatccct tcaaataatg ctcttacctt
     2341 ttctgactta ggtagataag attgttcata gtattttgat aaaaccttgc tatttcttcc
     2401 cttaacatat tctgatttat caaatccttc aaaagtttga tttctttcta tagctatttt
     2461 catagaagct ttaattgaat agtatctaac cattgcaaaa aatacattag aaaaatctat
     2521 agcatcatct gaagtatata aaatattttc tcttactaag tatccatgta aattcatagc
     2581 tcctaatcct atagaatgag acttgctgtt actattgctt accgttggca ctggttttat
     2641 atctgtgcta tctgctacaa atgacagtgc tcttattgct gtttcaactg tactttctat
     2701 agttttatta tccattacat tggctatgtt taaagaacct aggttacaac ttatatcttg
     2761 tccccattca ttttttcctc catacccctc tatttctgaa ggtgtttgat attgaaatat
     2821 ctcacaacat aagttagaca ttttaataat tccaacatct tttaatgtat gttctctatt
     2881 agctgtatct atgtacacta catatggata tccactttct tgttgcatct gtgctatttt
     2941 tgtcaacatc tgcctaggat ttatttcttt ttttcttata tcactatcat taaccagttt
     3001 atcataccac ttatccattt ctatctcatc aagagaaact ccatatttct tatacacagt
     3061 atgaggataa aatgcatatg ctacttcatt tttttctgcc aactccataa atttatctgg
     3121 tattatagct cctaatgata atgtagcaag ccttattttt tcatctgcat ttatcttttt
     3181 agtatccatc aacaattcaa aatcaggatg gaatacagta aggtacaccg caccagaacc
     3241 ttgtctagct cccatttgat taaagtaact aaatgattgt tctaacattt tagctactcc
     3301 aacaacacct ccagctgcac cttctatatc tttgatagat tcgccagatg ctctaagttt
     3361 agataaattt agtgcaactc ctccaccaat ctttgataag tgatttgatg aagatatagc
     3421 atacgatata ccttctgtac tatcttctac agatagtaaa aaacatgata ccatttctcc
     3481 agcccttttt cttccagcat ttaaaaaagt aggtgtagct ggttgaaatt cttgttttac
     3541 tattttatct gccaagttta aagctaaatc tttatcgcca tttcctagtg tcaaagctac
     3601 aattaacact ttatcattat atgtttctaa tatttccttt ccatcattgc tctttaatgc
     3661 ataattttga taaaacttat ttgcactcat atatgattga aattcaaact tatgtttatc
     3721 aatcatatca tatatatttt taataacatc tatgctatac tgatttatta cttcttttga
     3781 ataataacct tcatctatta aatacttcaa tctttcttct aggttattaa attttctcaa
     3841 ctttggctgt ataaattctt ctatgtaact acttaaggct tccttatcct tttccaattg
     3901 gtacttgcct tgttcatttt taattatcac ttgattgtta agctctatcc aattcattat
     3961 ttaccgtcct tttaacataa tcttgtgcca taatttcact taatttgctt attatttctt
     4021 ttggtactta tcagttgaaa tcccaaaatt aatctataat tatagaaatg caataagtat
     4081 ttttcaaaaa caaaagcact acatatagtc agtgctttat ctattatata ctacatatag
     4141 tatatacaca aattttttta tatctaaact tttattactt tataattgac attattttta
     4201 tttaaagaaa tttttatcaa ctcaaatata aaacaataca agcttattat gtcctgttta
     4261 aaaatttaaa ttatctctaa atagcttaaa aatatattct gatatattga aaaaagtact
     4321 ttcaagatga tattttatat attatttaga agttttttat ttattgttat ataattaaat
     4381 atatgactat tttgctacta catatataaa aataaattta tgaaggtgat tttaatgaaa
     4441 actatttcta aacaagaatt agaaaaaaca cttgagaaac attatttatg gcttaaaaac
     4501 aataatgctg gagaaaaggc agatttaaaa gaattaagat tagaaaatat ggacttaaga
     4561 ggatactgct taagtaatat tgacttttcg tggtctgacc ttatcaattt aaatttagaa
     4621 aaagcagatt tagaaaactc tatttttaat aattcttatc tttcggattg ttcattaaaa
     4681 aattctatat taaaaaatgc agacttaagt ggtgcaagtt ttagattttg tgacttatct
     4741 aactcagata ttagaggagc taatttagaa aattccaatt tagaatatgc tactttaaat
     4801 ggagtaatat cagatgaaag tactcgtttt tttaaattgt attgtcctga aacaggagca
     4861 tttataggct ataaaaaatg ttttaatttt agaatggtac aattattaat acccagcgac
     4921 gcaaaaagag tgtctgctac atcaaatgct tgtagatgtg ataaggcaaa agtactgtca
     4981 attactagtg tagatggtaa agaatctttt aaaagtgctc gtgcatatgc tgatgaaaat
     5041 tttatatata gagtaggaga aacgattgta gctgaagatt ttaatgaaaa tagatggaaa
     5101 gaatcgacta cagggattca ctttttttta actagagagg aagctattgg ttatctataa
     5161 aatgctaaag ttttataaat atataaatac ataaacaaaa taacaaaaga gtatagattg
     5221 taatttcaaa aaaattataa tctatactct tttttctata acacataagt acattttatt
     5281 tcataaatta taataaatta tttatatctg cactattgat tatttgagaa actttatcta
     5341 tatgttctat cttactatcc aaactgtcat aatacttctt actctcatct ctatttctaa
     5401 aagaataaac ttttttatcc aattttaaag cttcttttat aatatctata ttcctcttat
     5461 ttgtctctcc tacactaaat cctgtatcta ttataatctt ggaatcattt aaatttctaa
     5521 tagccaaatc gaaactctca tcacttatag gctcaaatgg attttctgta aacatcttta
     5581 tccccatagt tctaccaatt tcataatcaa tatcattttc atgtattatt ccagaataca
     5641 gacctatacc ttttttagta aaagctctat aaattggtgt tgctttaccc ccaccaccaa
     5701 ttataaaaac ttcattttta gatttattac taatttctac tgaacctaaa agactattaa
     5761 agtttttatc atccaattca taaagcgaat ttataatatc ctcatctact acatcttcag
     5821 gctggccata agctatgact ttattatttt ttataagagc aactttatca caacttttta
     5881 atgctatgtc tatttcatgc aatgaaagta ttactgatat tgacttttct ttacttaatt
     5941 ttttcagtat gtttatgagt tccaatctat gttttatatc caagtgagtt gtaggctcat
     6001 ctaatataat tatttctggt tcttgaacaa gagcccttgc aaccaacacc ttttgttttt
     6061 ctccatcact tagttcatca aaatatcttt tctttaaatg taaggcatct acagactcca
     6121 atgcttcatc taccattatt aaatctttct tagatagact cccaaaaaat cctgtatatg
     6181 gataccttcc tatattgact atatcttgta cagtcattaa atcacctaat aatctatttg
     6241 taagtactaa agccattttt tttgataatg cttttcttga tatacaattt atgtttacac
     6301 cattcaaata tatttcacct tttattggtg atataagttt agataaggac cttaataggg
     6361 tagtttttcc agctccatta cttcccaaaa gacatagtat ttctccattt tttacttcta
     6421 catttatatt acttataaca actttgttat tgtatcctac acttaaatta ttagttttca
     6481 acatgtctaa gccctatcct tccttttcac caataacatt actacaattg gagctcctaa
     6541 taaagatgtt attgtactta ttggtaattc tactggtgat aaaattactc ttgatattaa
     6601 atcacaaaga gctgtaacta tactgcctaa aaatattact actggtatca aaactctatt
     6661 atctgatgtt ttaaatatca tttttgaaat ttgtggcact gcaagtccaa taaaccctat
     6721 aggtcctgca aatgctgata ctattgctgc taatatacta gatataaata ctatcaaaac
     6781 tctaaaaaat cttatattta tgccaatact ttttgcatac tcttctccta gtaaaaaagc
     6841 atttaaaggt tttattatga atacagtcat caaaagacct aatataccaa ctattataag
     6901 tatttctacc ttttcccatg taaatccaga aaaacttccc atagaccaca tagtaaattc
     6961 ttttaattta tcactatttg caaatgattg taacacattt gttataccac tacatacata
     7021 tccggtcata attcctatta ttaaaagagt tgttatattc tttaccttat ttgcaaataa
     7081 aatgactata gacattacaa ttaaagctcc tataaaagct gctacaaata tactcattga
     7141 atttacactc tcaaatccca atgtgtatcc tcccaaaatc atgagagcta ctgataaagt
     7201 agaacctgaa gatactccta atatatacgg ttcaactatt gggtttttaa aaaatatctg
     7261 taataaaata cctgatactg ctaggcatgc tccacctacc atggttgcaa gtactctagg
     7321 gattcttata ttgtatatta ttttataatg ttctgtatta tccatacctc ttaatacaac
     7381 atctattact tctttaaatt caatttttac agagccaaat gctacacaca ctaaaaaagt
     7441 aagtatcata cttataatta atactataaa tattgtcgta ttccttattc tcattttatt
     7501 gataaaatcc atttgtatac tccttttagc aaagctatat taactaaaat ctataaaacc
     7561 tatctttttg tgtcctctct gtactattta tcataattta tataatgttt gattttttca
     7621 cctgtagtac ctgggtggaa catctcaact aaatctacta ttaattcgtc tgtcttatct
     7681 actgattgat aataatctgg agcaaacacc cataggttcc cgttttttac aacatccaaa
     7741 tcagccaata caggtgcact agattttata gaatctaaat ttggtgcata atctgaactt
     7801 gatgagtata caaatatatc tgcatctttt gcaacttcat gcaattgttc aatacttact
     7861 cgcccttcat ttgaatctat tgaagcacat gcatttattc caccagccat ttttatcata
     7921 ttatccacat atgaatcttt aggagctata taagcacttc cttcatatac agatgcccat
     7981 acaactttag gtttagcttt gttttttatt tttttactta cttcttctac cttttgtaca
     8041 gttttattta gttcactagt agccatatct tctttatcat aaaatgcagc tattaaactt
     8101 gtccactcca ttcttccaaa tggattttgc tctttatact cattgtctac aacataatta
     8161 agccctaatt cttttaattt gtcaataaat tttgtatcag cctctgataa accactactc
     8221 actatagtta agtcaggatt taagtctact attttttcat aatctggtgc taaatttgaa
     8281 ccaacgtaat gtatttttcc atctttcatt aaatctttaa tttctttaat agtccagtac
     8341 tgctcttgtg ttgttacggc ttttatacta tctagttcat ctattgttct tagagaacaa
     8401 gcctgtgttg tagatgctat taatacattg tccacaggcg ttctaactat attagcattt
     8461 ttatattttt caggaatttt aatcttcttt gggattaaaa tcagttctcg attatctcca
     8521 tcagttactt ttttaattcc atcttctaaa tcttcaacac taaatccact agcatatttt
     8581 aattctaatt tcttaccagt actagcttgt ttattctctt tgtcactttt actacaccct
     8641 ataagacctc ctaccataaa aattaccata gcaattaaaa aaaactgctt taaaacattt
     8701 gatttaaatt tcatctcttt cactccaata tcttattttt tatgagtggc taaaaaactt
     8761 taataatata tgctttttaa agtatactta ttaaagttat cctaaagtca tctttaataa
     8821 gtataacctt ttaataaaat aaaaaacttc tcctaattta ataaggagaa gttcatatat
     8881 caactttaca aaaacgaatt gatacttcat tttattataa attacaatct ccaccctaaa
     8941 ttgaacttat ataatactgg gcaggtctcc tgactcacgg cttttcctcc atcacccttc
     9001 ccaaaatttt tataaatttc agtggatttt gatttcgtat ccgtatacag tagcgggggc
     9061 tgtagtgaat tttcatcact ttccctatta aactaatata gtaccctagt attattttaa
     9121 tttaattttt attaagataa ttgtaattta ttgttgacct ctttgcaagg ttgatttaac
     9181 atatatttaa ttcattcatc aattttttaa tttcacatac ttgtttttca tttggtttta
     9241 caaatggagc agtcatataa tcacttattt gtaaccctct gatattcata gcttttttca
     9301 ttgctggtat aaatggattg gttattaagt aaaaatccat tgctttatta atatattttt
     9361 gaatttctat aaccttctcc atatctctat tattgtaagc ttcagcccat ttggagcaaa
     9421 cttctggaat taaatttgat aaccccccta tacaacctgc tcccccagac attagattat
     9481 gtataaagtt ttcatcataa ccactataaa ccttaaattc tgggaactct attttcatag
     9541 tatttattaa atctctggta tgtcccatca aagttactgt atccttatat ccaactatgt
     9601 ttttatgttt tcttgcaagt cttaatgtaa gttctggact taaatcataa ccagttctat
     9661 ctggataatt gtacaaatat atttcagcct ctgtattctt agctatttca ctataaaata
     9721 actcaatact atcatcatca agagagaaat aataagggct tattatcata acaccatctg
     9781 ctccactatt atgtgcatag tttgaaagtt ctatagattc atttatacac atacgacttg
     9841 tacctataaa cacttttact ctcttattta catgactagt tactaaatct ataagttctt
     9901 tttgcatatc catagacata ttaaagaact ctccagtact tcccattatg actagtccat
     9961 ctacacctcc atctataaga tggtcataca cttttttatt accttcttta tctaaatttc
    10021 cttcttcatc aaatattgta acaactggtg tcaaaaattc tgctttcata atttaaactc
    10081 ctaaaattta ttttaatatg ttcattaata catcagattt agctttaata ttaattatat
    10141 taaaacagtt acttaatgta attttttaaa attccaatac tctcaatctc acattcaact
    10201 acatctccac tactcatata tcgaggaggt gaaaatccca tccctactcc agaaggtgtt
    10261 ccagtagcta taatgtctcc agcctctaaa gtcatacctt ttgaaagttc tgaaactatg
    10321 tctgaaacgt ctgatatgaa taaccctgta ttagaacttt gtctttcttc accatttacc
    10381 ctactacata ctttaagttt tatgggaaaa ggaactgcac ttttatgtaa aatacatgga
    10441 cctaaagagg taaatgtatc taatcctttt cctctaaacc attgaacatg ttctttttgc
    10501 aactttctag cagaaatatc atttataaca gtgtaaccaa agatataatc ttctacctct
    10561 tcttttctaa tattaacacc tgttttacct attactactc caagttcaac ttcatagtct
    10621 agttgattat ttatctcaaa atgaccatct atctcatctt ctggacctat tgcctttgtc
    10681 acacgttttg taaaataaac cgttttttgt ggttcttcaa aactatcatc aaagtgagtt
    10741 tgagtttctt caagatggtc tttatagttc actcccacac ataagatatc atgtattggt
    10801 ttttctatag gaacatgtac agtacatctc tctcttttaa aaacatcata attatagaat
    10861 gtactttcat ttataatagt tttcaactta ataatatctt cactagatac attttgaatt
    10921 aattcattta aatccttaaa atttctactg agatttaaag agttaacatc tataataaat
    10981 aattcatctt tagaaaaaac tccagttctt ttacattcat tttctccttc agtaaaactt
    11041 acaaacttca taatctcacc ctttattaaa attctatgta tttattttct tacttaaaga
    11101 ttatacatag ttgcatactc tagctattgc catttcagta tatccaaggg actctgcttt
    11161 tgattgtttt ccatttgcta catctacaac catatttaac aaatcatctg ttaattcttc
    11221 cattgtttgt ggaccatata taactggact agcatcaaaa tccagattat cttccatatt
    11281 tgcaaaagtt attttatttc cagttatttt tattactggt gctattggat ttcctgatgg
    11341 tgttcctctt cctgtactaa ataccactat ttgtgctcct cctgctacca taccagcaac
    11401 agatgaagca tcatttccag gggtatccat tataacaaga cctttcttat caatttgttt
    11461 ggcataatca tatacttcac ttatttgtct atgaccacct ttatgtatac aaccaagtga
    11521 tttttcttct aaacttgtta aaccaccagc tatatttcca ggagatggat taccttctct
    11581 aacttcttct ccaaccaatt ttaatgaatt ttcatatcta tgtactatat gtaatatttt
    11641 ttcttttact tcttcattta ctgctctcct agctagtata tgctctgcac ctataaattc
    11701 agtagtttca cttaaaattg atgttgctcc taaatcgaca agtttatcac ttaattcacc
    11761 tattaatgga tttgctgcta atccacttgt tgggtcagac ccaccacatt cagttcctag
    11821 tataagttca gatattggaa attcttcttt tctaagcaaa gaagcttctt gtgccatttc
    11881 tctagcataa cgaacagctt tttctatagt ttttaaagtt ccatgttctt cttgtattac
    11941 aagagttttt attggcttat ttgttctctc ttttattgca tcaactacca aatcattttg
    12001 gcaattttcg catcccaaag atacaactat tacaccatat acatttggat ttgctgcata
    12061 accagccata acatccatag ttaattgttg gtctgaatgt acttgtgaac atccattctg
    12121 attattaaag gtaactgccc cttgaacttg tgatgctatt attctagttg tatctgatgc
    12181 acacacactc gtaggcaata ttaatatgtg gtttcttata ccaactcttc catctggtct
    12241 tttatatcca taaaatttca tactgatttc ctcctaaaat agtctatata ctttctataa
    12301 tttttatata ttataatttt tattacactc actaatcaaa cagctaaaaa cctatttaaa
    12361 aactatttga cactaaaatc aatgaataca acttttataa ctctataaat attattttat
    12421 atattagtca taacttgttt atccaaatcc tctctaacac ttctaacatt atgaatatgt
    12481 acatgttgac cactttttat ctcctgattt gcttctccta tatgttcacc atatttagta
    12541 actttatcac cttgggccat atcttttata gccaatttat gataaatagt tatatcatct
    12601 agtgctgtaa tcgtttttac tgttttgtct tttaatttaa aactaatttc actaccttta
    12661 gctattgctt caatagctac tgcaacatta tctttttcat caattatcac tgcatttatc
    12721 attattcttg ctctccttta taaataatat aattttatta atatcctaaa atctaattaa
    12781 agaatttatt attttaccaa caactcactg taatataaat taagctgtta ttgtaccatc
    12841 ctcattttgt tttgggaact taggacatcc atacttctta gcccaccaac tagttataag
    12901 aggtactaat attgcagtga caactactgc ggctgccact tgtgttgtag ctgttgcaac
    12961 atatggttgc catgatgggt caactaatgc aacagcagca ggtacagcaa ttgcatttcc
    13021 agcagttgta gctacagccc atcctgcata tcctggacgt tttcctataa atttatcaca
    13081 gaatactata aatatacctc ctacaaatac agatattaat ccaagtaata ctcctgataa
    13141 acctcctttt agtatacttg caagatttat gctactacca agtgcaaacc ctacaaaagg
    13201 tacgagtaaa ttacaccctg gctctaaaaa ctctttcatt tttttgtcaa aatttcctat
    13261 tatcatacca acaagtattg gcactattgc agccaataat gacaacaatg gtacatttgc
    13321 aagacctgaa gtcccaagag ctattaatgt aaaaaatggt ccatcattta aagtaagtaa
    13381 actcatagtt gcacaatctg tttcatctcc atatgaagtc atcaatgaaa gatatatact
    13441 accattacta tttgtaactg cacttataac agccaatgtt gtaagaccaa ggacaccatc
    13501 cattccaaat agctttccta taagtatacc tatcaaagca cctatagcaa atttagaacc
    13561 aagaagtata ccacctctct ttaaaacttt tggcatttct ctaaattgaa gctgagttcc
    13621 caagcatacc agttgaaccc caattatagt tgcagaccca acacttgaaa atactgctgt
    13681 cgtaaacgaa cctatttgta caatatctgg gcaaaaggta ttaatgaaag ctgctataaa
    13741 cattggcact atcatcatac ctgcaggaat ttttttaata aaatccatta tcataaagtt
    13801 aatcctccta aaacatgata tttaattact cttattaagt ttttagcttt aattctaacg
    13861 gccgtttcgg ttcgtattta agaactaagt ttttaattac gaatctttga attaatgata
    13921 gcattttcct atttatgagt caataaaaaa aataaatttt tgtcaaaatt ttttcaaact
    13981 ttctgataat accttgtata ttatcaaatg acttccttat atgcaaaaat acagcgtatt
    14041 taaaattata
//
LOCUS       DAYAOO010000100        13987 bp    DNA     linear   BCT 12-OCT-2024
DEFINITION  TPA_asm: Clostridioides difficile isolate ST8-SSI-h139-18
            SAMN40601845-rid21577343.denovo.101, whole genome shotgun sequence.
ACCESSION   DAYAOO010000100 DAYAOO010000000
VERSION     DAYAOO010000100.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN40601845
            Sequence Read Archive: SRR28438827
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 13987)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13987)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-MAY-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-MAY-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002157583.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002157583.1
            Genome Coverage       :: 163x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/11/2024 16:19:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 4,038
            CDSs (total)                      :: 3,963
            Genes (coding)                    :: 3,930
            CDSs (with protein)               :: 3,930
            Genes (RNA)                       :: 75
            rRNAs                             :: 6, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 60
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 33
            CDSs (without protein)            :: 33
            Pseudo Genes (ambiguous residues) :: 0 of 33
            Pseudo Genes (frameshifted)       :: 7 of 33
            Pseudo Genes (incomplete)         :: 25 of 33
            Pseudo Genes (internal stop)      :: 11 of 33
            Pseudo Genes (multiple problems)  :: 8 of 33
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13987
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN40601845-rid21577343.denovo.101"
                     /isolate="ST8-SSI-h139-18"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Denmark"
                     /collection_date="2018"
                     /collected_by="Statens Serum Institute"
     gene            141..770
                     /locus_tag="ACGI5H_003299"
     CDS             141..770
                     /locus_tag="ACGI5H_003299"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903387.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9698989.1"
                     /translation="MNKYLLINPVAERMYGEKFHLIKANLIKKGYIIAECEPQLEYVK
                     KQYKEYTKKTENTMLDCRCPESISLLKRNNLINDFEVPMIEPILVRTCRVLYDKYIKS
                     KDDMLVVTCPCTQLRDFASEKFKDKGNAMFYTWKEFAEQEGVKSLGKIDESPIPLGYF
                     KDTFEKVLEVSSEDEILSEIQKIRNGFEDKYDIVEMFYCKDGCNNGDGL"
     gene            771..1553
                     /locus_tag="ACGI5H_003300"
     CDS             771..1553
                     /locus_tag="ACGI5H_003300"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429083.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HFG9698990.1"
                     /translation="MVNKFNNKFLRLVKSVLIFFIILLLWKITNYLGIWSDYILPSPE
                     KVYSTFLNMISDGSIFINVYASMKRVLIGFAISTAIGVPLGIFFGIYSGVYEYFKSLI
                     NFLRNTPPLALIPMLILWFGIGEESKIIIIVLASFFPIFTSTLKGIKNCDSKLIEVGR
                     VFEFSKLQIIFKIIIPNAILDIAVGLKLALGYSFRAIIGAELVAASSGLGYLISDGKE
                     MSRTDVVIVGIIVIGLLGIITDYIFSIIVKKVSKGKMVEAYE"
     gene            1546..2424
                     /locus_tag="ACGI5H_003301"
     CDS             1546..2424
                     /locus_tag="ACGI5H_003301"
                     /EC_number="7.6.2.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728980.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HFG9698991.1"
                     /translation="MNNLVCDSGYIIRNLYKSYKVDNEEHVVLSDISLNIDRNHITVI
                     LGESGCGKTTLLRAIASLEGINSGEIRFINDNKEYRPNVGFVFQESRLMPWLNVSENI
                     AFHNQRKNTILNKVLRKFKHNKRISSKIINDNFRSLETNDNLNKSNKYNRKSNIDVEK
                     YLKMMNLQKFKNSYPNELSGGMAQRVSIARALSFNPDMLLMDEPFSALDYFTRIDMQN
                     EVIRIHKSTNKGVIFVTHDIDEALKIGKKIVVFTDERKVKEFNIEDGYNRDLTSDYYI
                     KLKKDILMTMKSNKGI"
     gene            2457..3416
                     /locus_tag="ACGI5H_003302"
     CDS             2457..3416
                     /locus_tag="ACGI5H_003302"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728979.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HFG9698992.1"
                     /translation="MKLKKLLIGITILTLATASLAGCAKKNNGEKLSEINLTYVKSPL
                     NVPSIIQKQDDLFGKEFKKDNIKVNFHEITTGPEQTQALAAGEIDFLHALGGTSALIA
                     ASNGVELKILNTYSRSPKGFMILTNNNSIKSAADLVGKKVAGPKGTILHQVLISALDK
                     EGLSMDDVEFVNMGIPEASAALSDGSVDAALIAGPAALKAMKSGSKLVANGEGLVDGI
                     IVTAVSTDFAEKHPEIVERFMKVEKETLEYVNNNFDEAMEKVAKEVDLSLEETKELYA
                     WYDFSLDITDKDISSLEDTQDFLIKNKLQEKKVNIKELIYNAK"
     gene            3731..4423
                     /locus_tag="ACGI5H_003303"
     CDS             3731..4423
                     /locus_tag="ACGI5H_003303"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429090.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator"
                     /protein_id="HFG9698993.1"
                     /translation="MSYKVYIVEDDISISTLLKDYIEKYGFEVIVEENFDDIMITFES
                     FKPHLVLLDVNLPKFDGFYWCRCIRQQSNLPIIFISARDGNVDQIRALESGADDYITK
                     PFYYDVVMAKIKSHIRRVYGEYSPKIDERIVELDGLKFYPERLELELNGENLIITKKE
                     GILIECLIKRYPKVVSRDYLLEKIWDDIEFVEENTLNVNVSRIRKRFEELGIDNAVQT
                     VRGLGYKLNKNW"
     gene            4664..5437
                     /locus_tag="ACGI5H_003304"
     CDS             4664..5437
                     /locus_tag="ACGI5H_003304"
                     /inference="COORDINATES: protein motif:HMM:NF014567.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HFG9698994.1"
                     /translation="MYLGSSFLGRNISVILKQQHKLYQSMIQEHKKIHSEHLTFINQW
                     IHQMKTPISVISLQLQDYEGEEVTENIRKEIDRLNKGLDMAMHFARADNFQKDFIVEK
                     AKLNEIVSSIVNEEKRLFIKSGMIPKIQVDKFTYVYTDVKWMKFIIGQLITNGVKYSK
                     DYSNYLTIKSEENNKYVILSIIDEGIGIVSKDLKRVFDPFFTGENGRKFGESTGMGLY
                     LVKKVCDDLGHKVSIKSEVGKGTEVSIYFNKDVNSLIKV"
     gene            5705..6556
                     /locus_tag="ACGI5H_003305"
     CDS             5705..6556
                     /locus_tag="ACGI5H_003305"
                     /EC_number="3.6.1.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728978.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0050380 - undecaprenyl-diphosphatase
                     activity [Evidence IEA];
                     GO_process: GO:0016311 - dephosphorylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="undecaprenyl-diphosphate phosphatase"
                     /protein_id="HFG9698995.1"
                     /translation="MSLDVIFILKSVIIAIVEGLTEFIPVSSTGHMILVGNLIDFKGQ
                     FAEMFEVVIQLGAILAVVVLYWKKIKDSVIEFFKFIFTGGKEGKIGFRFGMNVIIGCI
                     PFAIIGVLFYDNIKSLFNLQSVIIGFIVGGILLLVVETLFRKKNHSTDNIDKITPIQA
                     LKVGTLQVLSAWPGMSRSASTIMGGWIAGLNSPTAAEFSFFLAVPAMVASSGKDLFEF
                     DYSIMTPTLWIALVVGFIVAFIVSIIVMEKFVNFLKKKPMRVFAVYRIIMGVVLAVLA
                     FTNIISV"
     gene            6660..7406
                     /locus_tag="ACGI5H_003306"
     CDS             6660..7406
                     /locus_tag="ACGI5H_003306"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903381.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HFG9698996.1"
                     /translation="MKILTVNNLSKVYGKKIIFNALNDINFSIEDGEFVGIMGPSGSG
                     KTTLLNMISTIDKPTTGTMELKGKNPLLLRGEELALLRRRELGFVFQDFNLLDTLTIG
                     ENIVLPLTLDKVSVKEQDERLNEVSTILGIKDLLGKRTFEVSGGQAQRTAIARALINN
                     PSILLADEPTGNLDSKSSKVVMELFQKINKENKVTTMMVTHDPLAASYCSRILFIKDG
                     SIYNEIYKGSSREQFYQEIMDVLTLLGGDN"
     gene            7406..9322
                     /locus_tag="ACGI5H_003307"
     CDS             7406..9322
                     /locus_tag="ACGI5H_003307"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439793.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="FtsX-like permease family protein"
                     /protein_id="HFG9698997.1"
                     /translation="MNIKQFAINNISRNIKAYLGYLASIVISSSLLFSFIMFTSHPDL
                     DVSQFPDYLKEGLKMSKIIAYLFLFFFVFYSVSVFLKSRYKEFGILYITGISKRQVMK
                     LIFIENMIINIVSSVIGIIIGLIFAKIFLVIMSTFLELSPLKFYIPFNAILSTLIYFM
                     ILAVLTSIFTSFIVKENQVLKLLKGTKTPKPEPKTSLMLAILSICLFIIAYYNAITST
                     DQYTTYLRLVPVTSLTIVATYLFFSQFSVFFMKKLKLNKRFYRKNTNMLWISNLIYKV
                     KDNARIFFLITITSAVAFTAIGTVYSFWKDVERQINLIYPNTIYYSTMTLHNDPKKPD
                     SKEKDKERMMFIENNLKKENVDYTRTNGEFKTVFPKKSDFNVRIMKESKYLEITETIG
                     VKSISFEDNECISLLSSSLPGNNNVKENIIVGNRGLKVAKQVEECVMPAYYKNMYVVK
                     DNFYDSIESKFIVDRFTAFEVEDSSKTIEICREFENKFNNESGMQPYLFFSKELMIGT
                     GKLMYSTFIFLAIFIGLIFFVTTSSFLYNKFYMDCQVDKKKYEQLNKLGMTYNEIKKA
                     STIEIGIVFLFPYVVAVIHSIFALTALKNSFDIEVASSAVLVMGSLFLVQIVYFFIVR
                     NNYLKEIRLNLVNF"
     gene            9605..9835
                     /locus_tag="ACGI5H_003308"
     CDS             9605..9835
                     /locus_tag="ACGI5H_003308"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HTH domain-containing protein"
                     /protein_id="HFG9698998.1"
                     /translation="MILIQSRGKMKCKELSEELEVSERQIKSYKMYLEQAGIFINSTP
                     GIYGGYEIDKCNSISLIKLLDSEVSIFISTKW"
     gene            10031..10459
                     /locus_tag="ACGI5H_003309"
     CDS             10031..10459
                     /locus_tag="ACGI5H_003309"
                     /EC_number="2.3.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903360.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetyltransferase"
                     /protein_id="HFG9698999.1"
                     /translation="MIKKLNSKDINKIMEIWEKSTIKAHDFISKEYWQNNYNTVKNEY
                     IPISDTFVYDDGDEIKGFISIIDKNFIGALFIKPKYQNLGIGGKLLDYATKKYKSLSL
                     AVYKDNKKAVVFYNKKGFNIVKEQVNEDSGFKEYIMEYSK"
     gene            complement(10913..11683)
                     /locus_tag="ACGI5H_003310"
     CDS             complement(10913..11683)
                     /locus_tag="ACGI5H_003310"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898073.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9699000.1"
                     /translation="MKVNENNIDEELDELSRKVYLESPDFWISISDKIIDKVFDEMLL
                     FFAVKYNYFNIVCFAIENNYLDLNMPSKNKKYTNIMEHLLDTSKQNEDKKIYNYLLSL
                     NKGNNLDERPILDELNCNISSDTFEKKDIYLPKYLCPSCNSNIFDTGYKVSNDITYKF
                     SSKEAEPIEMCSEVSSIRCCNCDELLEDITLDKLYNLCKIQNCNNCGSNLTKVGIIAK
                     KKMNFDENTEKFKDVSTFYCCGNCDSEISLSQREHFKI"
     gene            12007..12552
                     /locus_tag="ACGI5H_003311"
     CDS             12007..12552
                     /locus_tag="ACGI5H_003311"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891255.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="biotin transporter BioY"
                     /protein_id="HFG9699001.1"
                     /translation="MKNTKVNIQDLTKMSICVALLCISSYIYIPLPFTPAGVTAQTIM
                     INLIALILTPRQAFSTVGVYIMIGLIGIPVFGGGTSGIGKLLSPTGGFYFGFLFAALI
                     ISLLKGRNNDIKRYILITIFVGMPIIYFMGTVFMCYFNQMTVEAALFAAVVPFLIGDT
                     IKSVIASFLGTKLNNVLRRNL"
     gene            12584..13720
                     /locus_tag="ACGI5H_003312"
     CDS             12584..13720
                     /locus_tag="ACGI5H_003312"
                     /EC_number="2.3.1.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891252.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003985 - acetyl-CoA C-acetyltransferase
                     activity [Evidence IEA];
                     GO_process: GO:0006631 - fatty acid metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA C-acyltransferase"
                     /protein_id="HFG9699002.1"
                     /translation="MKEVFILGGLRSHIGLKNGIFQFVQPELLGASVLKDLIKKYEID
                     KIDEIICGNAVGTGGNIARLMTLTAGVSNEVPAFTVDMQCASAMMSIDIAFSKVKSGQ
                     CDLIIAGGFESSSLQPMRTYHKNDKRYNTNNPNYTVAQFSPDDNSQNSMLEGAERVAE
                     LYQIEKADLDFWVKESHKRAKEAREEKILEDIISPINNSTYDEGIRDKMSQRLLDRMP
                     SILGKETITNAANSCLINDGASFIIICSKKYLEHVKKKPKAKIINTCTIGTDATLSPT
                     SAIQAMDKLLEIESLNYLDVSAVEFNEAFAVIDVLFQRKYPELIDRYNIFGGALAYGH
                     PYGASGAIIALHLLKALEKTKGRYGICSIAAAGGLGSALLLERV"
     gene            13724..>13987
                     /locus_tag="ACGI5H_003313"
     CDS             13724..>13987
                     /locus_tag="ACGI5H_003313"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422637.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AMP-binding protein"
                     /protein_id="HFG9699003.1"
                     /translation="MNYYELLRIKKERHKNKNFLIIDGEKYTYENILSYSEELGKQIS
                     LGENIPILIYSKNIMFQLISFFAINYSKNIPIICHYNLSKKVLD"
BASE COUNT         5477 a         1365 c         2345 g         4800 t
ORIGIN      
        1 tttaatattt catttaaaat attaaaaaat gtagataaaa attgttttat taagaaaaaa
       61 ttaatatatt gacaaaattt aagtgctcat ttaaactatt aattgataat aatattcaat
      121 attaaataat aggaggcgtt atgaataaat atcttctaat aaatccagtg gcagaaagaa
      181 tgtatggaga aaagtttcac cttattaaag caaatttgat aaaaaagggg tacataatag
      241 cagaatgtga accacagtta gaatatgtaa aaaagcagta caaagagtat acaaaaaaga
      301 ctgaaaatac aatgttggat tgtagatgtc cagaaagtat aagtctttta aaaagaaata
      361 atttgataaa tgattttgaa gtacctatga tagaaccaat attagtaagg acttgtaggg
      421 ttttatacga taaatatata aaaagtaaag atgatatgtt ggtagtaacc tgtccatgta
      481 cacaattaag agactttgca agtgaaaagt ttaaggataa gggtaatgct atgttttata
      541 catggaaaga gtttgctgaa caagaaggtg taaaatcact tggaaaaata gatgaatcac
      601 caattccatt aggatatttc aaagatactt ttgaaaaagt tcttgaagta tcaagtgaag
      661 acgaaatatt aagtgaaata caaaaaataa gaaatggctt tgaagataag tatgacatag
      721 tagaaatgtt ttattgtaaa gatggttgta ataatggaga tggtttgtaa atggtcaata
      781 aatttaataa taagttttta aggctagtaa agagtgtttt gatatttttt ataattcttt
      841 tattatggaa aattacaaat tatcttggta tttggagtga ttatatatta ccatcacctg
      901 aaaaggtata tagtacattt ttaaatatga taagtgatgg ttcaatattt attaatgtat
      961 atgcaagtat gaaaagagtt ttgataggtt ttgcaataag tactgctata ggtgtgcctt
     1021 tagggatatt ctttggaatt tatagtggag tatacgaata ctttaaatct ctaataaatt
     1081 ttttaaggaa tacacctccc cttgctttaa taccaatgct tatattatgg tttggtatag
     1141 gagaggaatc aaaaattata attatagttt tagcatcctt tttcccaatc tttacaagca
     1201 cattgaaagg gattaaaaat tgtgactcaa aactgattga agtgggtaga gtatttgagt
     1261 tttcaaagct tcagataata tttaaaataa taataccaaa tgccattctt gatattgctg
     1321 ttgggttaaa gttagctctt ggatatagct ttagagccat tattggggca gaacttgtag
     1381 cagcttcatc tggtcttgga tacttgatat ctgatggaaa agaaatgtct agaacagatg
     1441 ttgttattgt aggtataatc gtaattggac ttttaggaat aattacagat tacatatttt
     1501 cgattattgt gaagaaggta agtaagggaa agatggtgga agcatatgaa taatttagta
     1561 tgtgactctg gatatataat tagaaattta tataaaagtt ataaagttga caatgaagaa
     1621 catgtagttc ttagtgatat ctctttaaac atagatagaa accatataac agtaatttta
     1681 ggtgaaagtg gttgtggaaa gactaccttg cttagagcaa ttgcatcact tgaaggtata
     1741 aatagtggtg aaattaggtt tattaatgat aataaagagt atagacctaa tgttggtttt
     1801 gtttttcagg agagcagatt aatgccttgg ttaaacgtaa gtgaaaatat agcttttcat
     1861 aatcaaagaa aaaatactat tttaaacaag gtgcttagaa aatttaaaca caataaaaga
     1921 attagcagta aaattataaa tgataatttt agaagcttag aaacaaatga taatttgaac
     1981 aaatcaaata aatataatag gaaaagtaat attgatgtag aaaaatatct taagatgatg
     2041 aacttgcaga aatttaaaaa ctcttatcca aatgaattgt caggaggtat ggcgcagaga
     2101 gtaagcatag ctagagctct ttctttcaat ccagatatgt tgcttatgga cgagcctttt
     2161 tcggcattag attattttac aaggattgat atgcaaaatg aagttataag aatacataag
     2221 tcaactaata aaggcgtgat atttgtaact catgatattg atgaagcgtt aaagataggc
     2281 aagaaaatag ttgttttcac agacgaaaga aaagtaaaag aatttaatat agaagatggt
     2341 tataatagag atttaacttc agattactat attaaattaa aaaaagatat tttaatgaca
     2401 atgaaatcaa ataaaggcat ttaaagaaat taataatatt ttaaggagta aagtaaatga
     2461 aattaaaaaa gctattgata ggtataacaa tattaacact tgcaacagca tctttagctg
     2521 gatgtgctaa aaaaaataat ggagaaaaac tttcagaaat aaatttaact tatgtaaaat
     2581 caccattaaa tgttccttct ataattcaaa aacaggatga tttatttgga aaggaattta
     2641 aaaaggataa tataaaagtt aatttccacg aaattactac aggtccagag caaacacaag
     2701 ctttagctgc tggagaaata gacttcttac atgcactagg tggtacatca gctttaatag
     2761 ctgcatctaa tggagtagag ttaaagatat taaacactta tagcaggtca ccaaaaggat
     2821 ttatgatttt gactaataat aattcaataa aatcagcagc agatttagta ggtaagaagg
     2881 tggcaggccc aaaagggact atattacatc aggtattgat ttcagcactt gataaagaag
     2941 gattaagtat ggatgatgtg gaatttgtta atatgggtat tccagaggca tcagcagctc
     3001 tttctgatgg cagcgtagat gctgcattga ttgctggtcc agcagctctt aaagctatga
     3061 agtcaggtag taaacttgta gcaaatggtg aaggtttagt agatggtata atagtaactg
     3121 ctgttagcac agactttgca gagaaacatc cagaaatagt tgaaagattt atgaaggttg
     3181 aaaaggaaac tttagaatat gtaaataata attttgatga agctatggaa aaagtagcta
     3241 aagaagttga tttaagtctt gaagaaacta aagaattata tgcttggtat gattttagtt
     3301 tagatataac agataaagac atatcttcgc ttgaagatac acaagacttc ttaataaaaa
     3361 ataagttaca agagaaaaaa gtgaacataa aagaattaat ctataatgct aagtagaaac
     3421 tatgataaaa taatactaag taagaaatat agtaaaagtt taagttacct tattaaggta
     3481 actttttcta ttttgaatta gtaatttcaa tttattttag aatgattagt tgataataat
     3541 gattaattaa tcataaaaag atactttttt atagagtttt attaagatgt ctaataatat
     3601 ggttatactt atgaagtcag taattgtgaa gttagtaata tgattaaatt tatatattgt
     3661 aaaaagatta taatatatta aaattggact gttaatatga tgagtaaata ggtatattag
     3721 gaggaattat atgagttata aagtatatat tgtggaagat gatatatcaa taagtacatt
     3781 acttaaagat tatattgaga aatatggatt tgaagtgatt gttgaagaaa actttgatga
     3841 tataatgatt acatttgaaa gttttaagcc acacttagtt ctattagatg taaatttacc
     3901 taaatttgat ggtttctact ggtgtagatg tattagacaa cagtcgaatt tacctataat
     3961 ttttatatca gctagagatg gtaatgtaga ccaaattaga gctttagaaa gtggagcaga
     4021 tgattatata acaaaacctt tttactatga tgtagtaatg gcaaaaataa agagtcatat
     4081 aagaagggta tatggtgaat attcacctaa aatagacgaa agaatagtgg agctagatgg
     4141 attaaagttt tatccagaga ggttagaact agaattaaat ggtgagaatc taattataac
     4201 taaaaaagaa ggtatactga ttgaatgtct tatcaagaga tacccaaaag tagtaagtag
     4261 agattatctt ttagaaaaga tatgggatga tattgagttt gtagaggaaa atactttaaa
     4321 tgtaaatgtt agcaggataa ggaaaagatt tgaggaatta ggtatagata atgctgttca
     4381 gactgtccga gggttaggat ataaattaaa taagaattgg taaggagaaa gtatgaagtt
     4441 atttttaaaa gattataaag gttatatttt tatatattat ataggcatag ttatgacaat
     4501 tatttactgt aatcttatga agtttattag ttttggagag agtttatata ttcttttatt
     4561 tagttctttt atattgttat gttttttaat atataagtat tataaaaata gagaagtata
     4621 taatctgttt gaaaaaggag tacattcttt ggaggagtca tttttgtatt taggaagctc
     4681 attcttgggg agaaatatat cagttatttt aaaacaacaa cataaattgt atcaatcaat
     4741 gatacaagag cataaaaaga tacatagtga acatttaact ttcatcaacc aatggattca
     4801 tcagatgaaa acaccaatat cagttataag ccttcagctt caagattatg agggagaaga
     4861 agtaactgaa aatataagaa aagaaataga tagattaaat aaagggttag atatggctat
     4921 gcattttgca agggcagata attttcagaa agactttata gttgaaaaag ccaaattaaa
     4981 tgaaattgta tctagtattg taaatgaaga aaaaaggtta tttataaaaa gtggaatgat
     5041 tcctaagatt caagtagaca aatttactta tgtttataca gatgtaaaat ggatgaaatt
     5101 tataataggt caattaatta caaatggagt gaaatattct aaagattata gtaactacct
     5161 aactataaaa tctgaagaaa ataataaata tgtaatttta agtataatag atgaaggaat
     5221 tggaattgtt tctaaagatt taaaaagggt atttgaccca ttttttacag gagaaaatgg
     5281 tcgtaagttt ggagaatcta caggtatggg tctttatcta gtaaaaaagg tatgcgatga
     5341 tttaggtcat aaagtaagta taaaatcaga agtaggaaaa ggtacagaag tttcaatcta
     5401 ctttaataaa gatgtaaata gtttaataaa ggtgtaaata gtttgataaa gatgtaaatt
     5461 atctgttaca atagggtttt tagttaattg tactttttta ttatacaatt tattaaatga
     5521 aatattcata gttaaataat caaaatttaa gagcgtttat ttgcaaacct tacatagatg
     5581 taaggtttgt gtaatgtttg cagatagtta aattttctaa tctaaattac aattaatata
     5641 agaaataaca taagagaaat aacataaaaa aagaaatttt gtaaaaaagg aaggatgttt
     5701 attgatgagt ttagatgtta tttttatatt gaaatcagtc ataatagcta tagtagaggg
     5761 gcttacagaa tttattccag tttcatctac aggtcatatg attttggttg gtaatttaat
     5821 agattttaag gggcaatttg ctgaaatgtt tgaggttgta atacaacttg gggctatatt
     5881 agcagtagta gtactttatt ggaaaaagat aaaagatagc gttatagaat tttttaaatt
     5941 tatatttact ggtggaaaag aaggaaagat tggttttaga tttggaatga atgtaattat
     6001 aggttgtata ccatttgcga ttataggagt tctattttac gataatataa aatcattgtt
     6061 taatttacaa tctgtaatta taggatttat agtgggtggg attttattat tagtagtaga
     6121 aactttgttt agaaaaaaga atcattccac agataatata gataaaatta ctccaataca
     6181 agctttaaag gttgggacat tacaagtttt gtctgcatgg ccaggtatgt caaggagtgc
     6241 atctactatt atgggtggat ggatagcagg acttaattct cctacagcag ctgagttttc
     6301 tttcttttta gcagtaccag ctatggtggc ttcttcagga aaagatttat ttgaatttga
     6361 ttattcaata atgacaccaa cattgtggat tgctttggta gttgggttta tagtagcttt
     6421 tattgtatca ataatagtta tggaaaaatt cgtgaatttt ttaaagaaaa aaccaatgag
     6481 agtgtttgct gtatacagaa taataatggg tgtagtactt gcagtattag cttttactaa
     6541 cataattagt gtatagaaaa aatagattta tcatctataa aaattaaact aagataaatt
     6601 ataattaaca attatatata tgttatttca aaaattaaat taggaaggat agttaaataa
     6661 tgaaaatttt aactgtaaat aatttaagta aagtatatgg taaaaaaata attttcaacg
     6721 cattaaatga cataaatttt agtatagaag atggagaatt tgtaggaatt atgggtccat
     6781 ctggtagtgg aaaaactact cttttaaata tgatttctac tattgacaag ccaactacag
     6841 gaactatgga attaaagggc aagaatcctt tattgttaag aggtgaggaa cttgcattac
     6901 ttagaagaag agagttaggt tttgtatttc aggattttaa tttattggat acattaacta
     6961 taggagaaaa tatagtattg ccattgacat tagataaggt cagtgtaaaa gagcaagatg
     7021 agagattgaa tgaagtatct acaatattag gtataaaaga tttattagga aaaagaactt
     7081 ttgaagtatc aggtggtcaa gctcagagga ctgctattgc tagagcattg attaacaatc
     7141 catcaatact tttagcagat gaaccaacag gtaatttaga ttcaaagtca tcaaaggttg
     7201 taatggagct atttcaaaag ataaataaag aaaataaagt tactactatg atggtaactc
     7261 atgacccatt agcagcgagc tactgtagta gaatcttatt cataaaagat gggtctatat
     7321 ataatgaaat atataagggt agtagtagag agcagtttta tcaagagata atggatgtac
     7381 ttacattatt gggaggcgat aactaatgaa tataaaacag tttgctatta acaatatttc
     7441 aagaaatatt aaagcgtatt taggatactt agcaagtatt gttatatcat cttcactgct
     7501 attttctttt attatgttta caagtcatcc agatttagat gtatctcaat ttcctgatta
     7561 tttaaaagaa ggtctcaaga tgagtaagat aattgcatat ctattcttat tcttctttgt
     7621 gttttattca gttagtgtgt ttcttaaaag tagatataaa gaatttggaa tactttatat
     7681 tacaggtata tcaaagcgcc aagtaatgaa attaatcttt atagaaaata tgataataaa
     7741 tatagtatct tctgtaattg gaataataat aggcttaatc tttgcaaaga tatttttagt
     7801 gattatgtct acttttttag aattatcacc attaaaattc tatataccat ttaatgcgat
     7861 attgtctact ttaatctatt ttatgatttt agctgtatta acatcaatat ttacttcttt
     7921 tatagttaaa gaaaatcagg tgttgaagtt acttaaaggt acaaaaactc caaaaccaga
     7981 gcctaaaaca tcactaatgc ttgctatatt aagtatttgt ttgtttataa tagcgtatta
     8041 taatgctatt acctcaaccg accaatatac aacatatctg cgcttagttc cagttacatc
     8101 ccttactata gtagcaactt acttgttctt ttctcaattt agtgtatttt ttatgaagaa
     8161 gctaaaacta aacaagagat tttatagaaa aaatacaaat atgctttgga tttcgaactt
     8221 gatttataag gtaaaggata atgctagaat atttttcttg ataactataa cttctgcagt
     8281 agcatttact gctataggta cagtttattc cttttggaaa gatgtagagc gtcaaattaa
     8341 tttaatatat cctaacacaa tatattattc aacaatgaca ttgcataatg accctaaaaa
     8401 gcctgatagc aaagaaaaag acaaggaaag aatgatgttt atagaaaata atctaaaaaa
     8461 agagaatgta gactatacaa ggactaatgg tgaatttaaa actgtatttc ccaagaaaag
     8521 tgattttaat gtcagaatta tgaaagaatc taagtactta gaaattacag aaactatagg
     8581 ggttaagtct ataagttttg aagataatga atgtatatca ttattatcat caagtttacc
     8641 aggaaataat aacgtcaaag aaaatattat tgtagggaat aggggtttaa aggtggcaaa
     8701 acaagtggaa gaatgtgtta tgccagcata ttacaaaaat atgtatgtgg taaaggataa
     8761 tttttatgat agtatagaat caaaatttat agtggataga tttactgcat ttgaagtaga
     8821 ggattcaagt aaaactatag agatatgcag agaatttgaa aataaattta ataatgagtc
     8881 agggatgcaa ccatatttgt ttttctctaa agaattaatg ataggaactg ggaaattaat
     8941 gtattctaca tttatatttt tagcaatatt tataggttta attttctttg ttactacaag
     9001 tagtttttta tataataaat tttatatgga ttgccaagtt gataagaaaa agtatgaaca
     9061 gttaaataaa ttgggtatga catataatga gattaaaaaa gcttcaacaa ttgagattgg
     9121 aatagtattt ttgtttcctt atgtagtggc tgttatacat tcaatatttg cacttactgc
     9181 acttaaaaat tcttttgata tagaagtagc atcatcagct gttttggtaa tgggaagctt
     9241 gttcttggtt caaatagttt atttttttat tgtaagaaat aattatttaa aagagataag
     9301 gttaaattta gtcaattttt agttactatt attaaatgat aataaaaagg gtttaaaatt
     9361 aattaatatt actggaatta tagatgttta ttttttcagt aatatttttt attgtattaa
     9421 ctattaaaat tttgtacaaa tataaaatat aatatggtaa atgtcaaaat tataaaaaaa
     9481 ttctacttat ataaaatata aagaggttat atgtacatat gtgtagaaat aaataataaa
     9541 aatatcaatt aatgttatta ggggggggtt actcattagt aaattagcta atacacttag
     9601 aatgatgata ttaattcaaa gcagaggcaa aatgaaatgc aaagaattat cagaagagtt
     9661 ggaagtaagt gaaaggcaaa taaaaagtta caagatgtat ttagagcaag ctggtatatt
     9721 tataaattca acacctggga tttatggtgg ttatgaaata gataaatgta atagcatatc
     9781 attaattaaa ttattagata gtgaagtttc aatttttata tcaactaagt ggtagataag
     9841 tagaatatta gcaatatcaa cgagtattta gaaacttatt ttatattaat aaagcagtat
     9901 ataaaattgt agaatcaaca atagcatata ctaaaacatc caccttatat taactaaatc
     9961 atatctaaat aaaatacact tacctacaaa cattataaaa tcaatacaaa aatgaggtga
    10021 aacaaaattt atgataaaga aattaaacag taaagacata aataaaatca tggaaatatg
    10081 ggaaaaaagt acaatcaaag cacatgactt tataagtaaa gaatactggc aaaataacta
    10141 taatactgtt aaaaacgaat atatacctat atcagataca tttgtatatg atgatggaga
    10201 tgaaataaaa ggatttataa gcataataga taaaaacttt ataggagctt tatttataaa
    10261 gcccaaatac caaaatctag gtatcggagg taaactttta gattatgcaa ctaaaaaata
    10321 taaaagtcta agcttagcag tatataaaga taataaaaaa gcagttgtgt tttataataa
    10381 aaaaggtttt aatatagtaa aagaacaagt aaatgaagat tcaggattta aagagtacat
    10441 aatggaatat agtaaataat atgattacat tctattaaaa ggataattaa tttattttct
    10501 agttgatttt ttaagagtaa tttttaaaat agactatatg aagataaaga tatttattat
    10561 agatgtaagt taatcagaat tgatatagct acaaaagagg aaaataaaat tgtatggtgt
    10621 atttcagatt taacaaattt actatttaaa gataataagt ttgatataat attaaagata
    10681 ctttcaccta taaactatag agtattgaaa gaattttaaa taattatgga atgctaataa
    10741 aggtttgtta aaatttaata attattagat tatagaaaat tgccatgaaa ttagttcatc
    10801 aagaactagt ttcatagcaa ttttaattct tataagtgta tttattttta cagatttaaa
    10861 aaacttatac agtatctaat aatgtaatct tattacttta gcctataaat atttaaatct
    10921 taaaatgttc tctttgagat aagcttattt cagagtcaca atttccacaa cagtaaaatg
    10981 ttgagacatc tttaaatttt tcagtattct catcaaagtt catttttttc tttgcaataa
    11041 ttcctacctt agttaaatta gaaccacaat tattacagtt ttgaattttg cataggttat
    11101 atagtttatc aagtgtaata tcttctaata attcatcaca attacaacat ctgatagaag
    11161 aaacttcact acacatttca ataggttcag cttctttaga agaaaattta tatgttatgt
    11221 catttgatac tttataacct gtatcaaata tattagaatt acaacttgga cataagtact
    11281 ttggaagata tatatctttt ttttcaaaag tatcactact aatattacag tttaattcat
    11341 ctaaaattgg tctttcatct aggttattac ctttatttaa gcttagaaga taattataaa
    11401 tttttttatc ttcattctgt tttgatgtat ctaacaaatg ctccattata ttagtgtatt
    11461 ttttgttttt tgaaggcatg tttaaatcca gataattgtt ttcaatagca aagcatacta
    11521 tattgaaata gttatattta actgcaaaaa ataataacat ttcatcaaat actttatcta
    11581 ttattttgtc agaaatactt atccaaaaat ctggtgactc taagtaaact ttcctactaa
    11641 gttcatctaa ctcttcatct atattatttt cattaacttt catatcatca cttcctttta
    11701 aatatcttgt gtataaacta tttgttacta ttttttatat aaaataaaat cttatataaa
    11761 aatatatcat attataattt acaagtatag tctaaataga gctgttttta agcaaagttt
    11821 tataaatgac tattaaaata taaagtaaca gtataaagtt tacttataaa ttaaatgtaa
    11881 acctaaataa ttataatagt tgacaaaaaa acgtctttat tttatactaa aacaaagctt
    11941 taatagaagc tttgtatatg tacatataaa ctaaatgaaa taagacatat gaagggaatt
    12001 ataaaaatga aaaatactaa agtaaatatt caagatttaa ctaaaatgtc aatatgtgta
    12061 gcattattgt gtatatcatc ttacatatat ataccattgc catttactcc agcaggagta
    12121 acagcacaaa caataatgat aaatttaata gctttgattt taacaccaag acaagcattt
    12181 agtacagttg gtgtatatat aatgataggt ttaattggga ttccagtatt tggtggaggt
    12241 acatctggta ttggaaagtt attaagccca acaggtggtt tttattttgg gtttttgttt
    12301 gcagcactaa ttattagttt attaaaagga cgaaataatg atattaagag atatatatta
    12361 ataacaattt ttgttggaat gcctattata tattttatgg gaacagtatt tatgtgctat
    12421 tttaatcaaa tgacagtaga agcagcactt tttgcagcag tagtaccatt tttaattgga
    12481 gatacaataa agtcagttat tgcatctttt ttaggcacta aactgaacaa tgtactcaga
    12541 agaaatctat gataaatcta taatataagg aagggtgtaa tgtatgaagg aagtttttat
    12601 attaggagga ttgagaagtc atataggtct aaaaaatgga atttttcaat ttgttcaacc
    12661 tgaattacta ggagcaagtg ttttaaaaga tttaattaaa aagtatgaaa ttgacaaaat
    12721 tgatgagatt atatgtggaa atgcagttgg gacaggaggg aatatagcta gattaatgac
    12781 tttaacagca ggagtgtcaa atgaagtacc tgcttttact gtggatatgc agtgtgcttc
    12841 tgctatgatg agtatagaca tagctttttc aaaggttaaa tctggtcagt gtgatttaat
    12901 tattgcaggt ggttttgaaa gtagttctct gcaaccaatg cgcacatatc ataagaatga
    12961 taagcgatat aatacaaata atccaaatta tacagttgct caattttctc ctgatgataa
    13021 tagccaaaat agtatgctcg aaggtgcgga aagagtagca gagttatatc aaattgagaa
    13081 agcagacttg gatttttggg taaaggaaag tcataaaaga gcaaaagaag caagagagga
    13141 aaaaatactt gaagatatta tatctcctat aaataatagt acctatgatg aaggtatacg
    13201 tgataagatg agtcaaaggt tattagatag gatgccatca attttaggaa aagaaactat
    13261 tacaaatgca gcaaattcat gtcttattaa tgatggagct tcatttatta taatatgttc
    13321 taagaagtat ttagaacatg taaaaaagaa gcctaaagca aaaattatta acacatgcac
    13381 gataggaaca gatgcaacct taagtccaac atcagcgata caagcaatgg ataaactttt
    13441 agagatagaa agccttaatt atttagatgt atctgctgtt gaatttaatg aagcatttgc
    13501 agttatagat gtgttgtttc aaagaaagta tccagagtta atagatagat ataatatatt
    13561 tggtggagct ttagcgtatg gacatccata tggtgcttca ggtgcaatta ttgcattaca
    13621 tcttttaaaa gcattagaaa agactaaggg tagatatgga atttgctcta tagctgcagc
    13681 tggtggtcta ggttcagctt tactgcttga aagggtgtag attatgaact attatgaact
    13741 tttaagaata aaaaaagaga ggcataaaaa taaaaatttt ttaattatag atggagaaaa
    13801 atatacttat gaaaatatat tgagttatag tgaggaacta ggaaagcaaa tttctttagg
    13861 tgaaaatatc ccaattttaa tatattctaa aaatataatg tttcagttga ttagtttttt
    13921 tgctattaat tattcaaaaa atattcctat tatttgtcat tataatcttt ctaaaaaagt
    13981 attagat
//
LOCUS       DAYAOO010000101        13662 bp    DNA     linear   BCT 12-OCT-2024
DEFINITION  TPA_asm: Clostridioides difficile isolate ST8-SSI-h139-18
            SAMN40601845-rid21577343.denovo.102, whole genome shotgun sequence.
ACCESSION   DAYAOO010000101 DAYAOO010000000
VERSION     DAYAOO010000101.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN40601845
            Sequence Read Archive: SRR28438827
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 13662)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13662)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-MAY-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-MAY-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002157583.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002157583.1
            Genome Coverage       :: 163x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/11/2024 16:19:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 4,038
            CDSs (total)                      :: 3,963
            Genes (coding)                    :: 3,930
            CDSs (with protein)               :: 3,930
            Genes (RNA)                       :: 75
            rRNAs                             :: 6, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 60
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 33
            CDSs (without protein)            :: 33
            Pseudo Genes (ambiguous residues) :: 0 of 33
            Pseudo Genes (frameshifted)       :: 7 of 33
            Pseudo Genes (incomplete)         :: 25 of 33
            Pseudo Genes (internal stop)      :: 11 of 33
            Pseudo Genes (multiple problems)  :: 8 of 33
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13662
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN40601845-rid21577343.denovo.102"
                     /isolate="ST8-SSI-h139-18"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Denmark"
                     /collection_date="2018"
                     /collected_by="Statens Serum Institute"
     gene            338..751
                     /locus_tag="ACGI5H_003314"
     CDS             338..751
                     /locus_tag="ACGI5H_003314"
                     /EC_number="2.3.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905693.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:0016746 - acyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HFG9699004.1"
                     /translation="MELEITEKIEKQDEDTIFQGLLKYNLARLEDKNPVDLGIYIRDK
                     AGKIVAGFIGVTHGNWLSIKYLWVSEKLRYKGTGSQLLYKAEKIAKERGCKYVFLDTF
                     SFQAPKFYEKFGYHKVFSLENYPLTGKRYYYRKIL"
     gene            942..2159
                     /locus_tag="ACGI5H_003315"
     CDS             942..2159
                     /locus_tag="ACGI5H_003315"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428929.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M20 family metallo-hydrolase"
                     /protein_id="HFG9699005.1"
                     /translation="MLGKKCMDYLQTLGKISSTTNGLTRLILTQEHKKSIDLISSWME
                     GLNLDIEIDDIGNVIGTYKSSFPNAPTLVVASHQDSVKCGGIFDGMLGIIVPLVGLEE
                     AKHNNRSYPFNIKLIAFAEEEGTRFETSLMGSKVFAGTFKEELLKSVDENGITLEEAV
                     TKFGFNTKNLTNLHPRKDVDAYLEFHIEQGPVLENESLPAGIVSSITGFKSFKISVNG
                     KSGHAGTLPMNMRLDAGCCACECVLAIEKVAKTTTDLVATVGKMNFYPSSSNVVPERA
                     EFTLDVRSCSQEILDNSVEKIFNEISHICENRKLNYTSELAFENVPVPCSNKITKIIE
                     KSFIDLNLNPFYIYSGAGHDAQEMDNITDIGMVFIRCAGGVSHNPNESVSVDDLDTAV
                     KIFLKILDNLDLK"
     gene            2321..3019
                     /locus_tag="ACGI5H_003316"
     CDS             2321..3019
                     /locus_tag="ACGI5H_003316"
                     /EC_number="5.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428930.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0047661 - amino-acid racemase activity
                     [Evidence IEA];
                     GO_process: GO:0006520 - amino acid metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid racemase"
                     /protein_id="HFG9699006.1"
                     /translation="MNEKLIGILAGMGPRSTAPFVDLIIDECQSQYGAKYDDEFPKMM
                     IYSLPTPFYIDRPINHDLMKETIIDGLQKLESTGVNFIAMPCNSAHIYFKELKESINI
                     PILNIVEETVKKLPTISQKVTLFSTSSTFESTIYQNGIIHNGHEFIFKDEWQIKLNNL
                     IQNIKMDKENPHNIDIWNKLIEDVKNESIENIVIACTDLNVVLEKSYPSINIVDSSKC
                     LAESVVNKYLKLVK"
     gene            complement(3239..3856)
                     /locus_tag="ACGI5H_003317"
     CDS             complement(3239..3856)
                     /locus_tag="ACGI5H_003317"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435178.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4878 domain-containing protein"
                     /protein_id="HFG9699007.1"
                     /translation="MKKIILALTTFLLAISLTACSSAKPEDTIDSFFNSAKKFDFEGM
                     NKVMENNDEKYKDILKELDTKDPNAQYVLDYLKQNASKITYTIKDSEVKGDKATIKVE
                     CKFIDSTPLLQEIVAEAFTKMIGMSFSGQDLTDEKTTEMLVSIMKEKQKSVKETYVTK
                     NVEFECSKKDNKWIISSVNDAVADVLLSNLVTAGQEFSNSMNTLE"
     gene            complement(3983..5005)
                     /gene="argF"
                     /locus_tag="ACGI5H_003318"
     CDS             complement(3983..5005)
                     /gene="argF"
                     /locus_tag="ACGI5H_003318"
                     /EC_number="2.1.3.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428932.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004585 - ornithine carbamoyltransferase
                     activity [Evidence IEA];
                     GO_process: GO:0042450 - arginine biosynthetic process via
                     ornithine [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ornithine carbamoyltransferase"
                     /protein_id="HFG9699008.1"
                     /translation="MNNISLKGKSFLTLKDFTKEEIRYLLTLSSYLKTKKKVGIKGDL
                     LQGKNIALLFEKTSTRTRCSFEVAAHDEGAHVTYLGPNDCHMGKKESVSDTAKVLGRF
                     YDGIEFRGFKQETVESLAKYSGVPVWNGLTDEYHPTQILADFLTVIENVDKDLNKVKF
                     VYVGDARNNMGNSLMIGCAKMGIHFVALAPKELWPNEELVKEMKEIAKKSKGDIMLTE
                     NIDDVKGADVIYTDVWVSMGEEEQYEARINQLKDYQVNMDMIKKTENENVIFLHCLPA
                     FHDLETKVAQEIYEKFGLSELEVTNEVFNSKYSKVFEEAENRMHTIKAVMVSTMTDVN
                     MNNNLI"
     gene            complement(5114..6301)
                     /locus_tag="ACGI5H_003319"
     CDS             complement(5114..6301)
                     /locus_tag="ACGI5H_003319"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate aminotransferase family protein"
                     /protein_id="HFG9699009.1"
                     /translation="MNNDNTISKWNEYFIDTYNQPNFVIDYGEGSCFFDTNGNKYIDF
                     TSGYGVSSLGYSNSNLKNALKEQVDKLLHTSNLYFNEPVLYSGEKIINSSGMAKVYFC
                     NSGTEANETAFKIARKYSSDKYGNGRGTIISLKDSFHGRTMMSLMATGMDKYHKYFYP
                     LPEGFKYIERNNIEDLKNNLDSTVCAIILEAIQGEGGVNVLEKDYVLEIVKICQEKDI
                     VVIFDEVQCGIGRTGKLFGYEYFDVKPDIVTVAKGLGAGIPVGGVLVNKKLSKVLGKG
                     DQGTTFGGNLLAMVAASVVLDEISKDGFYNEVLEKGNYIRKSIESFNNKVILKTKGIG
                     LMIGIETNIESSIIEEKARKKGLLILTAGKNVLRFLPPLTISYKEIDEALEILKDILL
                     EIN"
     gene            complement(6331..7191)
                     /gene="argB"
                     /locus_tag="ACGI5H_003320"
     CDS             complement(6331..7191)
                     /gene="argB"
                     /locus_tag="ACGI5H_003320"
                     /EC_number="2.7.2.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890002.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0003991 - acetylglutamate kinase activity
                     [Evidence IEA];
                     GO_process: GO:0006592 - ornithine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="acetylglutamate kinase"
                     /protein_id="HFG9699010.1"
                     /translation="MINIEKANTLIEALPYIEKHQGKTIVVKYGGSAMKKDGLKESVM
                     EDLVLMSYVGINIVLVHGGGAEINKMLAKVDIESKFVNGLRYTDEETMEIVKMVLAGK
                     VNKDLVNKIHTKGGKAVGLCGIDNNMILCDPYKNYELGFVGEIKKVNVELIESCLKSG
                     YISVIATIGVGDDGETYNINGDTAASAIAKELNADKLILLTDVPGLLREPDEEKSLIT
                     EVILEDVDKLFEEGIITGGMIPKIEGCVDALNNGVNRVHILDGRVPHSIITELFTDSG
                     IGTLIRKETE"
     gene            complement(7206..8423)
                     /gene="argJ"
                     /locus_tag="ACGI5H_003321"
     CDS             complement(7206..8423)
                     /gene="argJ"
                     /locus_tag="ACGI5H_003321"
                     /EC_number="2.3.1.1"
                     /EC_number="2.3.1.35"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893402.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004358 - glutamate N-acetyltransferase
                     activity [Evidence IEA];
                     GO_process: GO:0006526 - arginine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional glutamate
                     N-acetyltransferase/amino-acid acetyltransferase ArgJ"
                     /protein_id="HFG9699011.1"
                     /translation="MEIIKGGVTVSEGFFASGIHCGLRKNKEKRDLALVYSDVLCDAA
                     AVVTQNKVKGNPVYVTQEHIKNGKAQAIIVNSANANTFNGKEGLINAYKMAKFTSDKL
                     NIKESDVLVASTGVIGKPLNIDLIEENMDELVNNLSKQGHIGAREAIMTTDIIKKEIA
                     VAIMYGDKKITIGGMAKGSGMIHPNMATTLGFITTDANIDGVLLKEALKIAVDKSFNR
                     VSVDGDTSTNDMVMILANGKAKNDRINKKDEHYQVFLSALTYVCIELAKLVAKDGEGC
                     TKLIECYINGALSEEHAVKLAKTVISSSLVKTAVFGADANWGRILCALGYAGEEIDME
                     KVDIIFESMKGYIEVCKNGNGLDFNEEKAKKILEDDEISILVDLNMGNARGNAWGCDL
                     SYDYVRINGSYRN"
     gene            complement(8464..9498)
                     /gene="argC"
                     /locus_tag="ACGI5H_003322"
     CDS             complement(8464..9498)
                     /gene="argC"
                     /locus_tag="ACGI5H_003322"
                     /EC_number="1.2.1.38"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861435.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003942 -
                     N-acetyl-gamma-glutamyl-phosphate reductase activity
                     [Evidence IEA];
                     GO_function: GO:0070401 - NADP+ binding [Evidence IEA];
                     GO_process: GO:0006526 - arginine biosynthetic process
                     [Evidence IEA];
                     GO_process: GO:0006592 - ornithine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetyl-gamma-glutamyl-phosphate reductase"
                     /protein_id="HFG9699012.1"
                     /translation="MNKIKVGIIGATGYVGAELIRLLMNHDKVEVTAIGSNSYVGKDI
                     VDIYPSIGYKNNMICIENEKVIDMCDVVFTALPHGVSEKFVIKAIKSKKKVIDLGADF
                     RIKDEEVYSKWYGVSFIDKILHKKAVYGLSEIYKEDIKDADIIANPGCYPTSISLPLM
                     PLLSSKLIKNNNIIIDSKSGLTGAGRELSISSHFTEVNENITAYKIGKHRHTPEIEQN
                     LSESCKEKVSVVFTPNLIPVNRGILSTIYCTKEDNISINDIHRKLTDYYEFKEFIEIL
                     PLDKVASLKNVRFSNKCVISLHENGDTLIICSAIDNMIKGAAGQAIQNMNIIFGIEEN
                     TGLKNIAPSF"
     misc_binding    complement(9752..9965)
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            complement(10183..10950)
                     /locus_tag="ACGI5H_003323"
     CDS             complement(10183..10950)
                     /locus_tag="ACGI5H_003323"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424252.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YoaP domain-containing protein"
                     /protein_id="HFG9699013.1"
                     /translation="MQIIDININNIDNEHICCSISEKKGENCVFSKKAWMKNNFDKGL
                     VFKRFDVRGKAFIEYIPAENAWCPITADNYIFINCFWISGKFKGQGYSNLLLQECVDD
                     AKSKGKYGLVVLSSSKKMPFLSDAKYLKYKDFCLADTSEPNYELLYFPFTDNAPIPYF
                     KNCVKKRKLNENGIVLYYSNQCPHTEKYAPILKKIANSRGIDVNLIKFETAKEAQNAP
                     APFTTYSLFFNGEFVTNEILSEKKIEKFLDTNIKKFN"
     gene            11249..11722
                     /locus_tag="ACGI5H_003324"
     CDS             11249..11722
                     /locus_tag="ACGI5H_003324"
                     /EC_number="2.3.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HFG9699014.1"
                     /translation="MFKEYLIRELKEDDIKNALDLIWNVFEEFESPDYCDEGITTFHQ
                     FIEYNSIIEKIKEKTLFFWGCFDSKKLIGVLAIRNLNHICMLFVDKNYHKHGVAKKLM
                     TTGIQYCICNKFNLTEITVNSSPYAVEVYHKLGFKDTAVEQIVDGIRFTPMKLLI"
     gene            complement(12091..12648)
                     /locus_tag="ACGI5H_003325"
     CDS             complement(12091..12648)
                     /locus_tag="ACGI5H_003325"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435154.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HFG9699015.1"
                     /translation="MRVSREIVIQATSDIVNKDGLNKVSLKVIAEKLGIRTPSLYNHI
                     ESLDDLLLEVAHKGMREMNSQMIKATIGNFGDTAIKCISIAYFNFIISNPGVYETIQW
                     ATWHGNNETLEIFDEYKSLLEKLILSCNLNTKNTGEVLNLIMSVLHGYSTLQLGKSLL
                     SKEEAIKGLADSIDTVLLGIHKKYD"
     gene            12906..13604
                     /locus_tag="ACGI5H_003326"
     CDS             12906..13604
                     /locus_tag="ACGI5H_003326"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729468.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HFG9699016.1"
                     /translation="MEKKYFEIHGVPSILWGNPSSKLYIYIHGQCGNKEEAEAFANIA
                     VPHECQVLSVDLPEHGERKREKNSFNPWHVVPELVSIMEYAKCHWNQISLYANSIGAW
                     FSMLSFEKENLRECIFVSPILDMQQLISNMMLWANVSEEQLKHELIIPTSFGHTLSWE
                     YLQYVKQHPITQWNVPTKILYGKHDELTEIGVVEKFVEKFNCNLTIIENGKHWFNTPQ
                     ELNSLYEWLNTLVK"
BASE COUNT         4664 a         2157 c         1507 g         5334 t
ORIGIN      
        1 tttatataat ttattcattt tataaattga actactaatg atattattga acatagcaat
       61 agaataacat ctaaaatagt ttttatgtat taaattaact tattttaata ttcaacaatt
      121 taggtttact aaatttattg atgatttctt tttatataac ttaaactaca tttttattta
      181 aaaaaattta atatcaacaa tataaaatta agaataagta ttattagttt gacattagca
      241 taaatgccta ttagaataat gttaaactat attctttcta ctgattttat taaaaaatac
      301 caatatacaa aagattatac aaggagaaag ttcaaatatg gaattagaaa ttacagaaaa
      361 aatagaaaaa caagatgaag atactatttt tcaaggatta ttaaaatata atcttgctag
      421 acttgaagat aaaaacccag tggatttagg aatatatatt cgagataaag caggtaaaat
      481 tgttgcaggt tttataggtg ttactcatgg taattggctt tctataaaat acttatgggt
      541 tagtgagaag cttagatata aaggtactgg aagtcaactt ttatataagg ctgaaaaaat
      601 tgctaaagaa cgaggttgta aatatgtttt tttagataca ttcagttttc aagcacctaa
      661 attttatgag aaatttggat accataaagt attttcactt gaaaattatc ctctaactgg
      721 aaagagatat tattatagaa aaatactata ataataaaaa tcatatttca tatttttaaa
      781 ttaaaacttc tgctcttcgt ctacagactt tatgttttta tatcattatt aatactaaaa
      841 tagtatttta ctatacatac aaaattattt gaaagttcaa aaattataag tataaaagct
      901 aatcttagct taaataaaaa ttatattttt aggaggtaaa tatgttagga aaaaaatgta
      961 tggattatct acaaacatta ggaaaaataa gttcaacaac aaatggtctt acaagactta
     1021 tcttgactca agaacataaa aaatctattg atttaattag ttcatggatg gaaggtttaa
     1081 atcttgatat tgaaattgat gacattggaa acgttatagg tacatataaa tcaagctttc
     1141 caaatgctcc cacattagta gttgcatctc atcaagatag tgtaaagtgt ggaggtatat
     1201 ttgatggtat gttaggtata atagtgcctc tagttggtct tgaagaagca aaacacaata
     1261 ataggtctta tcctttcaat attaagctaa ttgctttcgc tgaagaggaa ggaactagat
     1321 ttgaaacttc tttaatggga agtaaagttt ttgctggtac ttttaaagag gaacttctta
     1381 aatctgttga tgaaaatgga attacacttg aagaagctgt aacaaagttt ggatttaata
     1441 caaaaaactt aacaaatttg catcctagaa aagatgtaga tgcatattta gaatttcata
     1501 ttgagcaggg tcctgtttta gaaaatgaat ctcttcctgc tggaattgta tcaagtatta
     1561 caggatttaa aagttttaag atatcagtaa atggtaagtc tggacatgct ggtacacttc
     1621 caatgaatat gagacttgat gctggatgtt gtgcctgtga atgtgtatta gctatcgaaa
     1681 aagtagctaa aacgactact gatttggttg ctactgtagg aaagatgaat ttctatccat
     1741 cttcatcaaa tgtggtacct gaaagagctg aatttacact cgatgtacgc tcttgttcac
     1801 aagaaattct tgataattct gtagaaaaga tatttaatga aatatcacat atatgtgaaa
     1861 atagaaaact taattataca agtgaacttg cttttgaaaa tgttcctgta ccatgttcta
     1921 ataaaataac aaaaatcata gaaaaaagtt ttatagattt aaatcttaat cctttttata
     1981 tttatagtgg tgctggccat gatgctcagg aaatggataa tataactgat attggtatgg
     2041 tatttataag atgcgctggg ggcgtaagtc ataatcctaa tgaaagtgtc tctgtagatg
     2101 acttggatac tgctgtaaaa atatttttaa aaatactaga taatcttgat ttaaaataat
     2161 tcttatataa gaaagtatat taaaatatat aatctaaaaa atcactttat atttatatta
     2221 tataagtgta caatataatc tattataaaa tataatttta tgcttttata gatttttatt
     2281 ttatacataa atatatttat atataaagga gataattttt atgaatgaaa aattaattgg
     2341 tattttggct ggaatgggtc caaggtcaac agcccctttt gttgatttaa ttattgatga
     2401 gtgtcaatct caatatggag caaaatatga tgatgaattt ccaaagatga tgatatattc
     2461 attacctacc ccattttata ttgaccgtcc aataaatcat gaccttatga aagaaactat
     2521 aattgatgga ttacaaaagc ttgaatcaac tggtgtaaat tttattgcaa tgccatgcaa
     2581 ttcagcacat atatacttta aagaattaaa agagtctatt aatataccaa tattaaatat
     2641 tgtagaagaa acagttaaaa aattacctac tatctcacaa aaagtaactc ttttttcgac
     2701 tagttcaact tttgagtcta caatttacca gaatggtata atacataatg gacatgaatt
     2761 tatatttaaa gatgaatggc aaataaaatt aaacaatctt attcaaaata taaaaatgga
     2821 taaagaaaat ccacacaata ttgatatttg gaataaactt attgaagatg ttaaaaatga
     2881 atctatagaa aatatagtaa ttgcttgtac tgatttaaat gtagttttag aaaaatcata
     2941 tccttcaata aatattgttg attcatcaaa atgcttggct gaatcagttg tcaataaata
     3001 tctaaaatta gttaaataaa tttttcatac actatattat aaaaaatata tgttataagt
     3061 ttattttaaa tagtatagac ttataacata tatcatagtt tcttgacaat atagaaatta
     3121 accatgtatt tcattatatt aataaaaagg ataccaaaaa tggtatcctt cataaatatt
     3181 tatatgttta tttataaaaa taatcatata tttattactt tactacacct aaacaatatt
     3241 attcaagtgt attcatagag ttagaaaatt cttgtcctgc tgtaacaaga ttagataaca
     3301 atacatcagc tactgcatca tttactgaac ttattatcca tttattatcc tttttagaac
     3361 attcaaactc tacatttttt gtaacataag tctctttaac gcttttttgt ttttctttca
     3421 taattgatac taacatttca gttgttttct catcagttaa gtcttgtcct gaaaaactca
     3481 taccaatcat ctttgtaaat gcctcagcta ctatttcttg aagtaatggt gttgaatcta
     3541 taaatttaca ttctactttg attgtagcct tatcaccttt aacctcgctg tcttttattg
     3601 tatatgtgat tttagatgca ttctgtttta gataatctaa aacatattgg gcatttgggt
     3661 cttttgtatc taattccttt aatatatcct tatatttttc gtcattattt tccattacct
     3721 tattcatgcc ttcaaagtca aactttttcg cactgttaaa aaaactatca attgtatctt
     3781 ctggttttgc acttgaacat gctgttaaag atattgctaa taaaaaagtt gttaaagcta
     3841 atatgatttt tttcatatct caaatcctcc ctcttaattt gttgatacat aagttatttt
     3901 aacatataat gagagttttt gaataatata tttaaaatat tttataaatt ttcattaaag
     3961 taaagtctat attaaaacat atctatatta aattattgtt catatttaca tcagtcatag
     4021 tagaaaccat aacagctttt attgtatgca ttctattttc agcttcttca aatacctttg
     4081 aatattttga attaaatacc tcgtttgtaa cctctaattc tgataatccg aacttttcat
     4141 aaatctcctg agcaacctta gtttctaaat catgaaatgc tggaagacag tgtaaaaata
     4201 taacattttc attttcagtt ttctttatca tatccatatt tacttgataa tctttaagtt
     4261 gatttattct tgcttcatat tgctcctctt ctcccataga aacccataca tctgtatata
     4321 taacatctgc acctttaaca tcatcaatat tttcagtcaa cattatatct cctttggatt
     4381 tcttggctat ttccttcatt tccttaacca attcttcatt tggccaaagt tccttaggtg
     4441 ctagtgctac gaaatgtatt cccattttag cacatcctat catcagtgag ttccccatat
     4501 tatttctagc atcaccaaca tatacaaatt taactttatt caaatcttta tctacatttt
     4561 caattactgt taaaaaatct gccagtattt gtgttggatg atattcatct gtaagtccat
     4621 tccaaacagg tacaccagaa tattttgcta gactttcaac tgtttcttgt ttaaagcctc
     4681 taaattctat tccatcatag aatcttccta gaacttttgc tgtatctgat acagactctt
     4741 ttttacccat atgacaatca tttggaccta gataagttac atgtgctcct tcatcatgag
     4801 ctgctacttc aaatgaacat ctagttcttg ttgatgtttt ctcaaataat aaagctatat
     4861 tttttccttg tagcaaatcg ccttttatac caactttttt cttagttttt aaataacttg
     4921 ataaagttaa taaatatcta atctcttctt ttgtaaaatc ctttaatgtc aaaaaactct
     4981 taccttttaa acttatatta ttcatattaa ttcgcccctt cttataaact ttttaaattc
     5041 aattaaactt gttagcactt tactttttta tttacttcta atttttatct ttaatcaact
     5101 attttttgaa tatttagtta atttctagta atatatcttt taggatttca agagcctcat
     5161 ctatttcctt ataactgatt gttaatggtg gtaaaaatct caatacattt tttccagcag
     5221 tcaaaataag caatcctttt tttctagctt tctcttctat aatactagat tcaatattag
     5281 tttcaattcc tatcattaga ccaatacctt ttgtctttaa tataactttg ttattaaaac
     5341 tttcaataga ttttcttata taatttcctt tttctaatac ttcattataa aagccatctt
     5401 tagatatctc atctaataca actgaagctg ccaccatagc taataaatta cctccaaaag
     5461 ttgtaccttg gtctcctttt cctagtactt ttgaaagttt tttatttacc aatactcctc
     5521 ctactggtat tcctgctccc aacccttttg ctacggtaac tatatctggt tttacatcaa
     5581 aatattcata gccaaaaagt ttaccagttc ttcctatacc gcattggact tcatcaaaaa
     5641 tcactacaat atccttttct tgacatattt ttactatttc caaaacataa tctttttcaa
     5701 gaacattaac tccaccttcg ccttgaatcg cttcaagaat tattgcacaa actgtggaat
     5761 caagattatt ttttaaatct tcaatattat ttctttctat atatttaaaa ccttcgggaa
     5821 gaggataaaa atacttatgg tatttgtcca taccagttgc cattaaagac atcattgttc
     5881 taccatgaaa agagtctttt aaacttatga tagttcctct accattacca tatttgtcac
     5941 tactatactt tcttgctatt ttgaatgctg tttcatttgc ttctgttcca gaattacaaa
     6001 aatatacttt agccattcca cttgaattaa ttattttctc tcctgaatac aacactggct
     6061 cattaaaata taaatttgaa gtatgtaata atttatctac ttgctctttt agagcattct
     6121 ttaaattact attactatac ccaagagaag atactccata tccacttgta aaatctatat
     6181 atttattgcc attagtatca aaaaaacaac ttccttcacc ataatctatg acaaaattgg
     6241 gttggttata tgtatctata aaatattcat tccattttga aattgtattg tcgttattca
     6301 ttcttattct cccctcttaa acttataatt ttattcagtt tcttttctta ttaatgtacc
     6361 tattccacta tcagtaaata gctctgttat tatagaatgt ggaactcttc catccaaaat
     6421 atgtacccta tttactccgt tatttaaggc atctacgcat ccctctattt taggtatcat
     6481 acctccagta attatacctt cttcaaataa tttatcaaca tcctctaata taacttctgt
     6541 tattaatgat ttttcttcat ctggctctct taacaaacca gggacatctg taagaagtat
     6601 caatttatct gcatttaact ctttagctat agcagaagct gctgtgtcac catttatatt
     6661 ataagtctct ccatcatctc caacacctat agttgcaatt actgaaatat aacctgactt
     6721 tagacaagat tctataagct caacatttac ttttttgatt tctcctacaa atccaagttc
     6781 ataattttta tatgggtcac ataaaatcat attattatct attccacaaa gccctactgc
     6841 ttttccacct tttgtatgta ttttatttac taagtcttta ttaacctttc cagcaagtac
     6901 catttttaca atttccatgg tctcttcatc tgtatatcta agaccattta caaatttact
     6961 ttctatatcc acttttgcta gcatcttatt gatttctgcc cctccaccat gtactaaaac
     7021 tatattgatt ccaacataac tcattaacac aaggtcttcc ataacagatt cttttagacc
     7081 atcttttttc attgcacttc caccatactt aactacaata gtctttccct gatgtttttc
     7141 tatatatggt aaagcttcta taagtgtatt tgctttttct atattaatca ttaaagtata
     7201 tcctcctaat ttctataact tccatttatt cttacataat catagcttaa atcacatccc
     7261 catgcatttc ctctggcatt gcccatattt aaatctacta atatacttat ttcgtcatct
     7321 tcaaggattt tttttgcttt ttcctcatta aaatctaatc catttccatt tttacatact
     7381 tcaatatatc ctttcatact ctcaaaaata atatcaactt tttccatatc tatttcttca
     7441 cctgcataac ctaaagcaca cagtattcta ccccaatttg cgtcagctcc aaatacagct
     7501 gtctttacta atgaagaaga tataactgtt tttgctaatt ttactgcatg ttcttcactt
     7561 aatgctccat ttatatagca ttcaattagt tttgtacatc cttctccatc ttttgcaaca
     7621 agtttagcaa gttctataca gacatatgta agtgcactca aaaatacttg ataatgttca
     7681 tcttttttgt ttattctatc attttttgct tttccatttg ctagaatcat taccatatca
     7741 ttagtacttg tatctccatc tacactaact ctattaaaac ttttgtcaac agcaattttt
     7801 aaagcttctt ttagcaaaac tccatcaata tttgcatctg tagttataaa tcctaacgtt
     7861 gttgccatat taggatgtat catgccagaa ccttttgcca tacctccaat agttattttt
     7921 ttatctccat acattattgc tactgctatt tcttttttta taatatcagt tgtcataata
     7981 gcttctcttg ctccaatatg accttgttta cttagattat tcactaattc atccatattt
     8041 tcttctatta aatctatatt taatggcttt cctataacac ctgtagatgc aaccaaaaca
     8101 tcactttctt taatatttaa tttatcactg gtgaatttag ccattttata agcatttata
     8161 agtccttctt ttccattaaa ggtattagca ttagcactat ttactatgat agcttgtgct
     8221 tttccatttt taatgtgttc ctgtgtaaca taaacaggat tgccctttac tttattttga
     8281 gttactactg ctgctgcatc acataaaaca tctgaataaa ccaaagctaa atctcttttt
     8341 tctttatttt ttctcaagcc acagtgaatc cctgaagcaa aaaatccttc tgaaactgta
     8401 actccaccct ttataatctc catatttatc ctcctaatta tatgagttta gtatttttta
     8461 tttctaaaat gatggtgcaa tattttttaa acctgtattt tcttcaatac caaatattat
     8521 attcatgttt tgtatagctt gacctgctgc tcccttaatc atattatcta tagctgaaca
     8581 gattatcaat gtatctccat tttcatgtaa tgatattaca catttatttg agaatctaac
     8641 attctttaaa gaagctacct tatctaatgg aagaatttct ataaattctt taaattcata
     8701 ataatcagtt aatttcctat gtatatcatt tatagaaata ttatcttctt ttgtacaata
     8761 tatagttgat aagattcccc tatttactgg gattaagttt ggtgtaaaaa ctacacttac
     8821 tttttctttg caggattcac ttaaattttg ttctatttct ggagtatgtc tgtgcttccc
     8881 tattttatat gcagtgatat tttcattaac ctccgtaaag tgactactaa tcgataattc
     8941 tctaccagca cctgtaagac ctgatttaga atcaattatt atattattat tttttatcaa
     9001 tttagaactt agtaatggca tcaatggtaa agaaatacta gttggataac atccaggatt
     9061 tgcaattata tctgcatctt ttatatcttc tttgtatatt tcacttaatc catatacagc
     9121 ttttttatgt aagattttat ctataaaaga tactccatac catttactat atacttcttc
     9181 atcttttatt ctaaagtcag cacctaaatc tataactttc tttttcgatt taattgcctt
     9241 tattacaaac ttttcactaa ctccatgtgg aagggctgta aatacaacat cacacatatc
     9301 tataactttt tcattttcta tacatatcat gttattttta tatcctatac ttggatatat
     9361 atcaactata tcttttccaa catacgaatt tgaacctatc gctgtcactt cgactttatc
     9421 atgattcatt aataatctaa tcaactctgc cccgacatat ccagttgcac caataatacc
     9481 aacttttatt ttattcattt tgttccctcc atttttatat tcaaatagtc ttaaaatcct
     9541 atctttccac tttactatat gataatcatt tgataatacg tagattaaaa tactctaatt
     9601 aaaacaaaaa accccttagc attataaata ctaagaggcg attttccgcg gtaccactct
     9661 tattggtaaa attacaataa tcattaaaac tcaaattaaa aagtatctac aaaatgtaca
     9721 tttaaaatta aaaaagcctc ttggtcaaag accaagagac gaatatacac ccgcgttacc
     9781 actctaattg ataagataat cttacccact ctaatctctt aaggcgagat tcaccaatta
     9841 ccatactatt acttctggta atctcctcca aagctctatt cacaataaaa ttcgttacta
     9901 ggcttccacc attcccagct ctctatcaac tagctttatg ctactctctt tttcacagga
     9961 tttcaattta ttttcttatt gttttatatg atagtttatt tttttaactt tgtcaatata
    10021 atttttaaat ttttggaaat attttctata tggttaattt ccagcatttt gtatctaaat
    10081 tgcgatataa tttttatatt tcattcgtca atttaaaaaa catccaaaat atattaaatt
    10141 ataaaataat atattttcaa aatacaatat ttacatctct ttttagttaa attttttaat
    10201 gttggtatct aaaaatttct caatcttttt ctcagaaagt atctcgttgg ttacaaattc
    10261 accattaaaa aaaagactgt atgtagtaaa tggtgcagga gcattttgtg cttcttttgc
    10321 tgtttcgaat tttataagat ttacatcaat acctctagaa tttgcaattt ttttcaaaat
    10381 aggagcatat ttttccgtat gtggacactg attactgtaa tataaaacta taccgttctc
    10441 atttaatttt ctttttttta cacaattctt aaaatatgga ataggagcat tatcagtaaa
    10501 aggaaaatat aatagctcat aatttggttc tgatgtatct gctaaacaaa agtccttata
    10561 ttttagatat ttagcatcag ataaaaaagg cattttttta ctagacgaaa gcacaactaa
    10621 tccatattta ccttttgatt ttgcatcatc aacacactct tgtagcaata gattagaata
    10681 tccttgaccc ttaaattttc cagatatcca aaaacagtta ataaatatat aattgtccgc
    10741 agtaatagga caccatgcat tttctgctgg aatatattct ataaaagctt tacctcttac
    10801 atcaaatcgt ttaaagacta gacctttatc aaaattattt ttcatccaag cttttttaga
    10861 aaaaacacaa ttttctcctt ttttttcaga aattgaacaa catatatgtt cattgtcaat
    10921 attatttata tttatatcaa taatctgcat acttatctcc ttttctaatt gcataataat
    10981 ttttaaatat attctatata tttttatctt aatattttga atacaacaac atcatgtcat
    11041 atatattttt attttacata atattatttt aagattatct gaattattaa attgtatata
    11101 taattaaata cattctatgg tctaactaca ctataatata aattatatat tatcataata
    11161 ttctaaattt ataaaacaaa ttgtattgaa ttgaatttat ttaagatata taattataat
    11221 taaaataata ataaaggtgt tgtttataat gttcaaagaa tacttaataa gagaattaaa
    11281 agaagatgat attaaaaatg cattagactt aatctggaac gtatttgaag aatttgaatc
    11341 tccagattat tgtgatgaag gaattacgac atttcatcaa tttatagaat ataactctat
    11401 tattgaaaaa atcaaagaaa aaactctctt cttttggggt tgttttgact ctaaaaaact
    11461 tattggagtc ttagctatta gaaatttaaa tcatatatgt atgttatttg tagataaaaa
    11521 ctatcataaa catggtgttg caaaaaaatt aatgactaca ggcatacaat actgtatttg
    11581 taataaattt aatttaactg aaataactgt aaattcatca ccttatgctg ttgaagttta
    11641 tcataaatta ggatttaaag atactgctgt tgagcaaatt gttgacggta tacgttttac
    11701 acctatgaaa ttgttaatat aataaattaa ataaaaagca aagtctctta aatattttat
    11761 agttactttg cttttaaacc aagatttaaa ataatactat cttttttgtt ttttaataat
    11821 atactttaaa atccttacta atatgaacta taatttattt tttgatatcc tttttgatta
    11881 acatataaat taattcaatt attaaacata aactatgttg tttctcttta tatctcttct
    11941 ttgtaaacaa tattgggcat ttgaaaataa atattcttaa aatatactgt tctcctgttg
    12001 attttccttt ggtacaaatg ataaaaattt aatttacatg ccccataatg aagtgttcaa
    12061 taaataagtt aaaataattt atttacctcc ttaatcatat tttttatgaa tacctaataa
    12121 cacagtatca atagaatcgg ctaaaccttt tatagcttct tctttactca aaagtgattt
    12181 cccaagttgc aaagtcgaat aaccatgaag tacactcatt attaagttta atacttcacc
    12241 tgtattcttt gtatttagat tacaagaaag aataagtttt tctaataagg atttatattc
    12301 atcaaagatt tctaatgttt cattatttcc atgccaagta gcccactgaa ttgtttcata
    12361 aacaccagga ttagaaatta taaaattaaa gtatgctata cttatacact ttatagctgt
    12421 atctccaaaa tttccaatag tcgcctttat catttgacta ttcatctctc tcattccttt
    12481 atgagctact tcaagtaata aatcatctag actttctata tgattgtaca aagatggtgt
    12541 acgtattcct agcttttctg caataacttt taaagaaact ttgttaagcc catctttatt
    12601 aactatatct gatgtagctt gtataactat ttctctacta acacgcatga ttttccctct
    12661 ttcatttaaa attaattact ttattagttt agctaatcta attagtttcg tcaattattg
    12721 taatttataa aattctttat actattataa aatcttgaca gtttaattat aatttaatat
    12781 aatactaatt gaattagttt taatactaat ataattagta ttatattaaa ttctatatta
    12841 caacattatt ttatagtttg attaatttaa caatcactaa tatatcaaac tgaaaggaga
    12901 tttttatgga aaaaaaatat ttcgaaattc atggagttcc ttcaatcctt tggggaaatc
    12961 cttcaagtaa attatatatt tacatacatg gacaatgtgg caataaagag gaggctgaag
    13021 cttttgctaa tattgcagtt ccacatgagt gtcaagtttt aagtgttgat ttgcctgaac
    13081 atggagaacg taaaagagaa aaaaattcat ttaacccatg gcatgttgtt ccagaattag
    13141 tatctattat ggaatatgca aagtgccact ggaatcaaat ttcgttatat gcaaatagca
    13201 ttggagcatg gtttagtatg ttaagctttg aaaaagagaa cttaagagag tgtatttttg
    13261 tatctccaat tctagatatg caacagctca tttcaaatat gatgctttgg gcaaatgtat
    13321 cagaagaaca gcttaaacat gaactaatta tcccaacttc atttgggcat actctttcat
    13381 gggaatatct acaatatgta aaacaacatc ctatcactca atggaatgta ccaacaaaaa
    13441 tattatatgg taaacatgat gaacttactg aaatcggtgt tgtagagaaa tttgtagaaa
    13501 agtttaattg caaccttact attatagaaa atggcaaaca ttggtttaac acaccacaag
    13561 aattaaattc attatatgaa tggttaaata ctttagttaa ataaaaaata attatattat
    13621 taatatgatt aaattattta taaatgttat ttaattaatt tt
//
LOCUS       DAYAOO010000102        13582 bp    DNA     linear   BCT 12-OCT-2024
DEFINITION  TPA_asm: Clostridioides difficile isolate ST8-SSI-h139-18
            SAMN40601845-rid21577343.denovo.103, whole genome shotgun sequence.
ACCESSION   DAYAOO010000102 DAYAOO010000000
VERSION     DAYAOO010000102.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN40601845
            Sequence Read Archive: SRR28438827
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 13582)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13582)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-MAY-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-MAY-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002157583.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002157583.1
            Genome Coverage       :: 163x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/11/2024 16:19:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 4,038
            CDSs (total)                      :: 3,963
            Genes (coding)                    :: 3,930
            CDSs (with protein)               :: 3,930
            Genes (RNA)                       :: 75
            rRNAs                             :: 6, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 60
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 33
            CDSs (without protein)            :: 33
            Pseudo Genes (ambiguous residues) :: 0 of 33
            Pseudo Genes (frameshifted)       :: 7 of 33
            Pseudo Genes (incomplete)         :: 25 of 33
            Pseudo Genes (internal stop)      :: 11 of 33
            Pseudo Genes (multiple problems)  :: 8 of 33
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13582
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN40601845-rid21577343.denovo.103"
                     /isolate="ST8-SSI-h139-18"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Denmark"
                     /collection_date="2018"
                     /collected_by="Statens Serum Institute"
     gene            865..1527
                     /locus_tag="ACGI5H_003327"
     CDS             865..1527
                     /locus_tag="ACGI5H_003327"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434446.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HFG9699017.1"
                     /translation="MSILEIKNLNKIYGKSETEVKALSQINLKINSGEFVVIVGKSGS
                     GKSTLLHIMAGLETPTNGDVIIDNINISSLDEKKRSALRKEKLGLIFQSYNLIPVLTV
                     EENIKLPTINIKNKDEAYINELMELLGIKDRRMYLPNQLSGGQQQRVAIARALVNKPS
                     IVFADEPTGNLDTKTESDVLSLLKESQKKYNQTIIMITHNIDITKYADRVIEIEDGFI
                     RE"
     gene            1536..4043
                     /locus_tag="ACGI5H_003328"
     CDS             1536..4043
                     /locus_tag="ACGI5H_003328"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009901674.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="FtsX-like permease family protein"
                     /protein_id="HFG9699018.1"
                     /translation="MKLNYIVKKYIMGNKKNTLLIIVSIVISTALFLIMNIISEDATN
                     LMINQAKNEFTLKHAQYINPKDEEIKYIENNTSIDKVGKSMLLGISDIGKGQTLQILS
                     QDKVAEELNDIYTLEKGKLPVAENEIAIDSWYIKQKKIKNPIGKRITLDYRRQGIDQE
                     DLYTGEKEFKITGILNSNPILKAQGTSIGLISNDCAIKNIPTKNKYDQVMFTFKKEKN
                     IQRQSQKLIKNGNLNENNIYFNNELLIAISDSMNLKIPYIIVNIVLALATILLIYNIF
                     YILVSNRIKDFGIFRALGFNPNDIFKIMILEVSIYSIISISIGLILGGIIASLSREYV
                     IGVIYNVNYINSIKNQNYINTYIISILLSLGTIIISVSKPLMLSVKTDPMICIRRNNE
                     KVDIKQNSFINKFMIKLFKDYGNIASKNIQRNKKRTNLSIASMVIIFFLMATIYTKST
                     SNFLSDGVLKYWIQGDYLLHNIDISTIRSNNKGYDKNVLQEIKAIDGVTKVNSYRHKW
                     FNIKIDDKSINKNSDYWKKNKDNIEARSEVKDGIKVYNNSFEFLGIEDTDILEDFLIN
                     GKENIDKFSKQPYLYITKKSSDSLNIKKGDRIKVYFDIIDSKTNNFTKTISQEFIVCG
                     IITTLPVTSQVGAEFGGVISTNQFNKFTGISSYERFDIWTSKLANDKYVESELNKITE
                     KTNKGILIPYKAETAEYEKIDNQKTLIMVLVTGIIVILSLFNCCNTIVTSINSRSREF
                     ALFRGIGISKHEINKIVKLESYIYIIVSFCISIIPILIVRSIIIKPFESINLINWKFI
                     GAIILIVFILVSIIMITTLKTLNKIQNENFMEEIKTL"
     gene            4374..4718
                     /locus_tag="ACGI5H_003329"
     CDS             4374..4718
                     /locus_tag="ACGI5H_003329"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895235.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9699019.1"
                     /translation="MYCLSVVLAIYGIYVFINCTEYIYTMLSTKHLTVKGNEYTIINY
                     YMSNFSQYIIFAILLASMGFVIQKIVHMHFSEIELSGNYSTTVRNISDISLDNDNEMF
                     NRGNIENSILKK"
     gene            4956..5642
                     /locus_tag="ACGI5H_003330"
     CDS             4956..5642
                     /locus_tag="ACGI5H_003330"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004453504.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000156 - phosphorelay response regulator
                     activity [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HFG9699020.1"
                     /translation="MSSILLVEDDLSLIYGLEYSIQKNGFSVDVARTVEEALQIYKEK
                     NYDLLLLDVSLPDGDGFDICKRVREASNVPIIFLTASDEEVNVVMGLDMGGDDYITKP
                     FKLNELISRIKALLRRYNFTSENVTELKSNNITVKLLENRVFKNEIELELTTAEYKLL
                     CLLMKNKNIVLTRKNILDKLWDGNGSFVDDNTLSVYVRRLRNKIEDNPENPKNLLTVR
                     RMGYKWNVIK"
     gene            5653..6894
                     /locus_tag="ACGI5H_003331"
     CDS             5653..6894
                     /locus_tag="ACGI5H_003331"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888761.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing sensor histidine kinase"
                     /protein_id="HFG9699021.1"
                     /translation="MKVFSNKDIKIFFLVIISVLLMFIVVGQIVVINITNDYKSALLE
                     HDYNIAGYLNSMGVDKSKIPAVFTTNEDKYTLKGKEILNTARYDFGTDDSFMPSVKLF
                     QGKYIKTMFLYLFVFFTMIIFILYVYFFRQQNKIEEASYKIDSFMNGNINVRLNTYEE
                     GSLSKLFGSIDAMSTSLNTHILKEKQNKEFLKNTISDISHQLKTPLTALMMYNQILQE
                     ESHNSEIVENFVQKSQNELERIESLIQNLLKITKIDSKTIILNKASVNVKKLITKILY
                     SFETRAEKEGKSISIRGLENTNLFCDYEWISEALSNLIKNALDNTKENDKIMIEWVET
                     PITTIISVSDTGNGIHIEDIHHIFKRFYRSKFSKSNQGLGLGLPLVKSIIEQHNGTIT
                     VESNFLQGSTFTLSFLKLTNM"
     gene            6965..7648
                     /locus_tag="ACGI5H_003332"
     CDS             6965..7648
                     /locus_tag="ACGI5H_003332"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002584132.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HFG9699022.1"
                     /translation="MDILVVNNLCKTYGNGYTKVEALKDVSFTVSKGEFVTVVGESGS
                     GKSTLLNLLGGLDTPTSGKIFVDGKEICSMKEEKQTIFRRRNIGFIFQSYNLIPELTV
                     EQNIIFPLLLDYKKPDTIYLDEVLTILGLKDRKSHLPNQLSGGQQQRVAIGRALITKP
                     SIILADEPTGNLDSKNSSDVISLLKVTAEKYNQTIIMITHNTNIASTADRILQVSDGM
                     LKDLGVNRE"
     gene            7645..9978
                     /locus_tag="ACGI5H_003333"
     CDS             7645..9978
                     /locus_tag="ACGI5H_003333"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009901677.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HFG9699023.1"
                     /translation="MRSYLELVPQYAKVHKKKNRTTILCIVIAVCLVTAIFGLADMAI
                     QCQKVQFIKDDGNWHIVLKNLNEEAISEISSRVDIAHYGRGQVIDNGEFKSKEILIQG
                     LDEDLAKQLGLEIIKGRYPVVENETLIDVDAVKSFNLKVGDFIKIKLADGRNKNYKIV
                     GEYSSLSRLRASDKHGLMLSILGTQAIKKSETYDYYYITFKDKVNIRKATSDIKNTFN
                     LSDKQIGKNEKLLSIIGQGDSDYSKPLYLTAGGLFILVLIASIIMIYNSFNMGVIERI
                     KFFGLLRCLGASKLQVKKFVVLESLILSVKAIPLGLLLGCIVTIISSIFLKYVNTELF
                     GSMPILKVSFIGIVFGIIVGFLTVILSAIVPAKKASGVSPLSAIRGNLMFKEILTSGK
                     ASKIANAGSSKIDVSMGINHAFSRKKSFILMTSSFAISIVLFLGFSVFIDFMYQALKP
                     IKPEAAHISIVDADFKSVLTKDDINEISNIKGIKKVYSRMMTDVEATYNNKEATSQLI
                     SYEKNQFDWAKKYLVKGEINEDKLESENIGLVEEGHGFNIGDKIYIKNGNSKKEIEVA
                     GILSSISFDVKDKYIGNIITSENTFTSITDIKDYIIIDTQVDEDAPEDLIQNIRNVLD
                     DNLEVRDKRQGNLEAKNSFYTMAVFVYGFVFIIAIISMFNIINSMNISVTSRINYYGI
                     MRAIGMSNKQLRKMVIVESSTYAVSGCLLGSVLGLILHRYIFVSLVTLKFHIDWQIPF
                     DLLFIIVVTMIIITLLAVRKPIKKICELDIIEVVNAQ"
     gene            complement(10086..10648)
                     /locus_tag="ACGI5H_003334"
                     /pseudo
     CDS             complement(10086..10648)
                     /locus_tag="ACGI5H_003334"
                     /inference="COORDINATES: protein motif:HMM:NF037635.4"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(10762..12111)
                     /locus_tag="ACGI5H_003335"
     CDS             complement(10762..12111)
                     /locus_tag="ACGI5H_003335"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009901680.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="APC family permease"
                     /protein_id="HFG9699024.1"
                     /translation="MEKAKKLGLFSMILLGINSIIGSGIFLLPGKVYNLAGQNSMFIY
                     IFATLLVLSILLCFAEVGSMFDKNGGAYLYSKKAFGDFIGFEVGTMSWVIRIISWSTL
                     AVGFATALGSFWPESATEYKGYIAAILVTLLSINSLFGIKSTKIMNNVITIAKLVPLI
                     VFIIVGIFFIKFVNIVPSGNVVNSSMGPAIILVFYAFTGFESFIVASGEMENPKKNLP
                     VALITTIFICAIIYILIQIVCMGILGDRLFENSIPIADASSVFLGNYGKFFISVATLI
                     SIFGINIGSSIVTPKCGSSLAEEGSLPAFIGKTNKYGAPYVAIIISLICCIPLVLTGS
                     FEQLAVMSVIARFAQYIPTCLSVIVLRKRTDVKASFKIPFGPVIPMVAILGSLWLLQQ
                     AWAEDISKPITQNRVLIGLGAMLLIAPLYIFMKKNKEIEHKNKSEDSKLYISREKIQ"
     gene            complement(12148..13368)
                     /locus_tag="ACGI5H_003336"
     CDS             complement(12148..13368)
                     /locus_tag="ACGI5H_003336"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888013.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M20 family metallopeptidase"
                     /protein_id="HFG9699025.1"
                     /translation="MQQALKLKYQTKELGKDFVIESCNSIKPWLINIRRELHKIPELA
                     LEENLTKQKVISYLKEIGIDYMEFTKHNGIMAYILKESADKTICIRADMDALPIEEEN
                     NIPYKSIHSGKMHACGHDAHTTMLLGACKVLHSIKDKLNVNVKFLFQPAEEGFGGAKF
                     LVEDGCLENPKVDYIFGLHVMPHIETGFIEIKYDTLNASVDTIKISIKGKRAHGAYPE
                     NGIDAIVTASQIVTSLQTIISRNLEPNNAAVLTIGKIYGGDAHNVICEDVKLEGTLRT
                     LNSKTRNFMIDKIAKIVGDTASAFGCVGTLHVSDENYPAVINEKELVDTVISNTKELL
                     GEEKFILRPNPSLGGEDFSFYTEHCKGAFFHLGCKNEEKGLISPLHTSSFNIDEDCLP
                     IGVMMHVMNTLYFN"
BASE COUNT         5379 a         1533 c         2045 g         4625 t
ORIGIN      
        1 aattaaaaat ataatgaaag tttagtttta attcatttat ttaataaaca tttcaagtaa
       61 aataatgttt aaatcagaaa tataaataaa tattattata atcgttatta aagaccaaaa
      121 atcccacctt agaagtttgt atcatatgaa acctttatag attatgaaag caataatata
      181 gtgtatgata tataaaataa gttataaaag tattttttta gatattcaaa aagacattgt
      241 aagttatatt aataatatgg gtatcaacga attttggata taatgagttt ttcaacttaa
      301 agttatgtaa taatgaatgt aaagaatatt taatgaaatc attttgttgg ttatgtctag
      361 ctgaatacaa taatctttta gataaagatt ttatatttga agataggtgt gaaaaaatta
      421 agaagatatt aacatcagca gtttagaggc aaagcatgta aagtaaagtc tgggtaacta
      481 aaagtagtaa tttagattgt aactattgtt ataaatatga aaatgaggaa acaggaaata
      541 taagttagga tgtagaaaat aggttactaa ataaaaagct taattatata atcaaagaaa
      601 taggtatata ctgtacaatt tcatggtgaa gaacttttcc taaataaaaa ggttggtaaa
      661 agagatataa gaaataaaat tcaattataa gatatggtat gataactaaa ggcactatat
      721 ggagtgaata ggcggaagaa ttttttgaaa attataaaaa tagtttctgt tgctacatat
      781 caataagtat agatagagat tgcaaaatcc atagcaaaaa tcgaatttat aagtgtaaat
      841 aacatgtaag acaaggagta aattatgagt attttagaga taaaaaacct aaataaaata
      901 tatggtaaat cggaaacaga ggtgaaagcg ttaagtcaaa taaatctaaa aataaatagt
      961 ggagaatttg ttgtgatagt aggtaaaagt ggaagtggga aaagtacttt actacacata
     1021 atggcaggac ttgaaactcc aacaaatggt gatgtgatta ttgataatat aaatatatca
     1081 tctcttgatg aaaagaaaag atctgcatta cgtaaagaaa agttgggatt aatatttcaa
     1141 tcatataatt tgattccagt tttaactgtt gaagaaaata taaaactacc aactataaat
     1201 ataaaaaata aagatgaagc ttatattaat gaattgatgg agttactagg aataaaagat
     1261 agaagaatgt atttgccaaa tcaattatca ggtgggcaac aacaaagagt agcaatagca
     1321 agggctcttg taaataaacc atcaattgta tttgctgatg aacctactgg aaatttagac
     1381 acaaagacag agtcagatgt attaagttta ttaaaagaat ctcaaaaaaa atataatcag
     1441 acaataataa tgataacaca taatatagat ataacaaaat atgctgatag agttatagaa
     1501 atagaagatg gatttataag agagtaggta gatttatgaa acttaattat attgtaaaaa
     1561 aatatataat gggaaataag aaaaatacat tattaataat tgtaagtatt gtaatttcaa
     1621 cagcgttgtt tttaattatg aatataataa gtgaagatgc gacaaactta atgataaatc
     1681 aagctaaaaa tgaatttaca ttaaaacatg cacaatatat caatccaaaa gacgaagaaa
     1741 taaaatatat agaaaataac acaagtatag ataaagttgg aaaatcaatg cttttaggaa
     1801 ttagtgatat tggtaaaggt caaacactac aaattctatc tcaggataaa gttgctgaag
     1861 aactaaatga tatttacaca ctagaaaaag gtaaattacc agtagctgaa aatgaaatcg
     1921 ctatagattc atggtatatt aaacaaaaaa agataaaaaa ccctatagga aaaaggataa
     1981 cattagatta tagaagacaa gggatagatc aagaagattt atatactggg gaaaaagaat
     2041 ttaaaataac tggtatctta aatagtaatc ctattttaaa agctcaagga acatcaattg
     2101 gccttataag taacgattgt gctatcaaga atattcctac taaaaataaa tatgatcaag
     2161 ttatgtttac ttttaaaaag gaaaaaaata tacagagaca atcacaaaaa cttattaaaa
     2221 atggaaattt gaatgagaat aacatttatt ttaataatga attattaata gctatatctg
     2281 atagtatgaa tttaaaaata ccttatataa tagttaatat agtactagca ctagcaacta
     2341 tattattaat ttataatatt ttttatatat tagtatcaaa tagaataaag gattttggga
     2401 tatttagggc tttagggttt aatccaaatg atatttttaa aataatgatt ttagaagtat
     2461 ctatatactc tattataagt atttctatag gtctaatttt aggtgggata atagctagtt
     2521 tatcaaggga gtatgttata ggagtaatat acaatgtcaa ctatataaat tctataaaaa
     2581 accagaacta tataaacaca tacataattt ctatattatt aagtttagga actataataa
     2641 tatcagtttc aaaacctctt atgttatcag ttaaaactga tccaatgatt tgtataagaa
     2701 gaaataatga aaaagtggat ataaaacaaa attcctttat aaataaattt atgataaaac
     2761 ttttcaaaga ctatggtaac atagcatcaa aaaatataca aagaaataag aaacgtacaa
     2821 atttatctat agcatcaatg gtaattatat ttttcttaat ggcaacaata tacacaaagt
     2881 ctactagtaa ctttttaagt gatggtgtat taaaatattg gatacaagga gattatttat
     2941 tacataatat tgatataagt actatacgtt caaataataa aggttatgat aaaaatgtac
     3001 tacaagagat aaaggcaatt gatggtgtaa caaaagtaaa ctcatatagg cataagtggt
     3061 ttaatataaa aattgatgat aaaagtataa ataagaactc tgattattgg aaaaaaaata
     3121 aagataatat tgaagctaga tcagaagtaa aagatggaat taaggtatat aataattctt
     3181 ttgaattttt aggaatagaa gatacagata tactagagga tttcttgata aatggaaagg
     3241 aaaatataga taaatttagt aaacaaccat atctgtatat aacaaagaaa tccagtgatt
     3301 cgcttaatat aaaaaaagga gatagaataa aagtatactt tgatattata gattcaaaaa
     3361 caaataattt taccaaaaca atatctcaag aatttatagt atgtggaatt ataactacat
     3421 taccagtaac ctcacaagtg ggagctgaat ttggcggagt aatatcaaca aatcaattta
     3481 ataagtttac aggaatatca tcttatgaaa gatttgacat atggacgagt aaactagcca
     3541 atgataaata tgttgaaagt gagttaaaca aaataacaga aaaaacaaat aaaggaattt
     3601 taattccata caaagctgaa acagctgaat atgaaaaaat tgataatcaa aaaacactaa
     3661 ttatggtatt agtaactgga attatagtta tattatcttt atttaattgt tgcaatacta
     3721 tagttactag tattaatagc agaagtaggg aatttgcact atttagagga ataggaatat
     3781 caaaacatga aataaataaa attgttaaat tggaaagtta tatatatatt atagtaagct
     3841 tttgtatatc tataatacct attttaattg taagaagtat aataataaaa ccttttgaaa
     3901 gtatcaattt aataaattgg aaatttatag gggctattat actaatagta tttattttag
     3961 tatctataat catgataact acactaaaaa cattgaataa aattcaaaat gaaaatttta
     4021 tggaagaaat aaagacttta tagtgaacag cctataaatt aaagaggttt tatatgaatt
     4081 taattgcaat tatcgataat ggtgtagata ttgattttaa ataatttaga aataaaaata
     4141 aaataagtta tccaagttat atgtatgatg taataggggt acaatgtata gcaaatataa
     4201 atattggctt aataaaactc tactcttaag tctactgtcg ttttaacaca agactaataa
     4261 taagtgtaac ctaaaaatta ttgataatac aataaccttg tttatgataa ataacaaata
     4321 ttaagtgttg taaagatagt aagtttaaaa aaatatcaaa gatttcaatc acaatgtatt
     4381 gtttatctgt agtgttagct atttatggta tatatgtatt tataaattgt actgaatata
     4441 tatatactat gctatctaca aaacatttaa cagtcaaagg aaatgaatat accattataa
     4501 attattatat gagtaacttt agtcagtata taatatttgc tattttactt gcatcaatgg
     4561 gatttgtaat acaaaagata gtgcatatgc atttcagtga gatagaactt agtggtaact
     4621 attcaacaac tgttagaaat ataagtgata tctctttaga taatgataat gaaatgttta
     4681 atagaggcaa tattgaaaat agtattttaa aaaaataaat aatataaata tataaaatgt
     4741 gattgaataa agcttagaat acttagtgta ttttaagctt tttttattat taagatttca
     4801 aagtattaaa ttaactatat aaaatcatat aaaaataatt ttaaaatatt taaatcattg
     4861 atttcaaggt attgtatttt taaaagagta aaaatataat aagttaggta tataatatat
     4921 ataaagtaaa aaataaaaaa atggaagtga ttgagatgag tagtatattg ttggttgaag
     4981 atgatttaag tttgatatat ggattagaat attctataca aaagaatgga tttagtgttg
     5041 atgtagcaag aacagtagaa gaagcattgc aaatttataa agaaaaaaat tatgatttac
     5101 tgcttttgga tgtatcctta cctgatggtg atggttttga tatttgtaaa agggtaagag
     5161 aagcttctaa tgtaccaatc atatttttaa ctgcttctga tgaagaagta aatgtagtga
     5221 tgggacttga tatgggtgga gatgattaca taacaaaacc ttttaaatta aatgagttaa
     5281 tttcaagaat aaaagcttta cttagacgtt ataattttac aagtgaaaat gtaactgaac
     5341 taaaatcaaa taatattact gttaaattac ttgaaaatcg tgtttttaaa aatgaaattg
     5401 agcttgaact tactacagca gaatataaat tattatgctt acttatgaaa aataaaaata
     5461 ttgtacttac aagaaaaaat atattggata agttatggga tggaaatggt agttttgtag
     5521 atgataatac tctgtcagta tatgtaagaa ggttaagaaa taagattgaa gataatcctg
     5581 aaaatccaaa aaatctatta acagttagaa gaatgggtta caaatggaat gttataaagt
     5641 gagggtgtta atatgaaggt attttctaat aaagacataa aaatattttt tttggtgatt
     5701 atatccgttt tattgatgtt tatagtagta ggtcaaatag tagttataaa tataactaat
     5761 gattataaaa gtgcactgtt agaacatgat tataatatag ctggatactt aaatagtatg
     5821 ggtgttgata aatcaaaaat accagcagta tttactacta atgaagataa atatacttta
     5881 aaaggaaaag aaatcttaaa tacagctaga tatgactttg gtacagatga tagttttatg
     5941 ccaagtgtga aattgtttca aggtaaatat ataaaaacta tgtttttgta tttatttgtg
     6001 ttctttacta tgattatttt tatattgtat gtgtattttt ttaggcaaca gaacaagata
     6061 gaagaagcta gttataaaat tgattcattt atgaatggaa atataaatgt acggttaaat
     6121 acttatgaag aaggtagttt atcaaagtta tttggttcaa tagatgctat gtcaacatct
     6181 ctaaacacac atatattgaa agaaaagcag aataaagaat ttcttaaaaa tacaatttca
     6241 gatatatcac atcaactaaa aactccactt acagcattga tgatgtataa tcaaatattg
     6301 caggaagaga gtcataatag tgaaattgtt gagaattttg tgcagaagag tcaaaatgaa
     6361 ttagagcgta tagaatcatt gatacaaaac ttgttaaaga ttacaaagat agattcaaag
     6421 acaataattc ttaacaaagc tagtgttaac gtaaaaaagt tgattactaa aattttatat
     6481 agttttgaaa ctagagcaga aaaagaagga aagagtatct ctataagagg tctagaaaat
     6541 acaaacttgt tttgcgatta tgaatggata tcagaagctt taagcaacct tataaaaaat
     6601 gcattagata atacaaaaga gaacgataaa ataatgatag aatgggttga aacacctata
     6661 acaactatta tttcagtgag tgataccgga aatggaattc atattgaaga tatacatcat
     6721 atatttaaaa gattttatag gagtaagttt tcaaaaagta atcaaggcct tggattaggg
     6781 ttgccactag ttaaatctat catagaacag cacaatggaa ccataactgt agaaagtaat
     6841 tttttacaag gaagtacatt tactctaagt tttttaaagc ttactaatat gtaagatagg
     6901 atacatctta cagtaaggtg tatgaattat tcttatatta atcatcagaa aggagataga
     6961 gcaaatggat attcttgtgg ttaataattt atgtaaaaca tatggaaatg gatatacaaa
     7021 agtagaggca ttaaaagatg tatcatttac agtttcaaag ggagagtttg ttactgtagt
     7081 tggagaatct ggctcaggta agagtacatt attaaatctt ttaggaggtc ttgatactcc
     7141 aacctcagga aaaatatttg ttgatggtaa agaaatatgt tcaatgaaag aagaaaaaca
     7201 gactattttt cgacgtcgta atataggttt tatctttcaa tcatataatc ttatacccga
     7261 attaactgtg gaacaaaata taatatttcc tttactacta gattacaaaa aaccagacac
     7321 tatttatcta gatgaagtat tgacaatttt aggtcttaaa gatagaaaaa gtcatcttcc
     7381 aaatcaatta tctggtggtc agcaacaaag ggttgcaatt ggaagagcat tgattacaaa
     7441 gccatcaatt atattggcag atgagccaac aggaaatctt gacagtaaaa atagcagtga
     7501 tgtaatttca cttttaaaag tgacagcaga aaaatataac caaactatta ttatgataac
     7561 tcataataca aatatagctt ctacagcaga taggatacta caggtttctg atggaatgct
     7621 taaagaccta ggggtgaata gagaatgaga agctatttag aactagtacc acaatatgca
     7681 aaggtacata agaaaaaaaa tagaactaca attttatgta ttgtcattgc agtatgttta
     7741 gttactgcta tttttggact agcagacatg gctatacaat gtcaaaaagt acaatttata
     7801 aaagatgatg gaaattggca catagtactt aaaaatctta atgaagaagc tatatcagaa
     7861 ataagtagta gagtagatat agctcactat ggtagaggac aagtcattga taatggagag
     7921 tttaaatcaa aggagatttt gatacaaggt ttagatgaag atttagcaaa acaattaggt
     7981 ctagaaataa taaaaggtcg ttatcctgtt gtggagaatg agactttaat agatgtagat
     8041 gcagttaaaa gctttaatct aaaagtagga gattttatca aaataaaatt agcagatggt
     8101 agaaataaaa attataagat agtaggtgaa tattcatcat tatcaagatt aagagcctca
     8161 gataagcatg gattaatgct ttcaatatta ggtacacaag ctatcaaaaa atcagaaaca
     8221 tatgattatt attatattac atttaaagac aaggttaata ttagaaaagc tacttctgat
     8281 attaagaata ccttcaattt aagtgataaa caaatcggta aaaatgaaaa attactttct
     8341 attataggtc aaggtgactc tgattattct aaaccacttt acttaacagc aggaggactt
     8401 tttatacttg tgttaatagc aagtattatc atgatatata atagctttaa tatgggtgta
     8461 atagagagaa taaagttttt tggactatta cgttgcttgg gagcatcaaa actccaagtc
     8521 aaaaaatttg ttgttttaga aagtttaatt ctaagtgtaa aggctattcc actaggattg
     8581 ttattaggat gtattgtaac cattatatcc tctatatttc tcaaatatgt gaatacagag
     8641 ttatttggtt cgatgccaat tttaaaggtt agctttattg gtattgtgtt tggaataata
     8701 gtaggatttt taacagtaat attatcagct attgttccag caaaaaaagc ttctggggtg
     8761 tctccactaa gtgctatacg tggtaatcta atgttcaaag aaattttaac tagtggaaaa
     8821 gcaagtaaaa ttgctaacgc aggaagttct aaaattgatg tttctatggg aataaatcat
     8881 gccttttcaa gaaaaaaatc ttttatactt atgacttctt catttgctat tagtattgta
     8941 ttgtttttag gttttagtgt atttatagac tttatgtatc aggcacttaa acctataaaa
     9001 ccagaagctg ctcatatatc tattgttgac gctgacttta agtctgttct tactaaagac
     9061 gatattaatg aaataagtaa tatcaaagga ataaaaaaag tatacagtag aatgatgacg
     9121 gatgtagagg ctacatacaa taataaggag gcaacatctc agctaatttc ttatgaaaaa
     9181 aatcaatttg actgggccaa aaagtatcta gtaaaagggg aaatcaatga agataaatta
     9241 gagtcagaaa atatcggatt ggtagaagaa ggtcatgggt ttaatattgg agataagata
     9301 tatattaaaa atggaaattc taagaaagag atagaggtag caggtatact ttcttcaatt
     9361 tcatttgatg ttaaagacaa atatattgga aatattataa catctgaaaa tacttttact
     9421 agtataacag atataaaaga ctatataata attgatactc aagttgatga agatgctcct
     9481 gaagatttaa tccaaaatat aagaaatgtt ctagatgata atttagaggt tcgagataag
     9541 cgacaaggta acttagaggc taaaaattca ttttacacta tggcagtttt tgtatatggg
     9601 tttgtattta taattgcgat tataagtatg tttaatatca taaacagtat gaatataagc
     9661 gttacaagta gaataaatta ctatggtatt atgcgtgcaa taggcatgtc caataagcaa
     9721 ttaagaaaaa tggtaatagt agaatcaagt acatatgctg taagtggctg tttattgggg
     9781 agtgtacttg gattaatatt acatagatat atatttgtat ccttagtaac attaaaattc
     9841 catatagact ggcaaatacc ttttgattta ctgtttatca ttgtagtaac tatgataata
     9901 ataactttgc ttgcagtaag aaaaccaatt aaaaagattt gtgaattaga cataatagag
     9961 gtagtaaatg cacaataaat ataagtagta atttaaatag aggtagtaat ttaaataaaa
    10021 aatcgaagta aatatgaaat agaaaatatc tttcataatt tacttcgatt tttgtgttat
    10081 ataatttact ttagataagt tccatcttca tcttgataaa ttaagtcttt cttcataagt
    10141 actccaagag cacgtttaaa attttcttac ttgaattaaa taagatagaa atatctttag
    10201 gatcagattt atcattgaat ctcatatatc catctgaacc ttctaaatag cttaaaatct
    10261 tattttctaa ggtatcaagt tcatcttttc tgtttcctct aggagaaagt cctaatttac
    10321 catcatcgta tatttttata acatgtaaat tttcaagaac atccccagct tttaattctg
    10381 taaagtattc attatgaagg attacaccag catatttatt gtcaacacat atcatagcag
    10441 agttgttggt ttggaatcca tatacaactc catttacaac atctcctaca ttgtaagtat
    10501 ggtctgtttc taaatatgaa tctatgtctg tagtagcagc tattcttccg cttttatcca
    10561 agtatatata gaataaatat ttttcatctc taaacaatgg ataagtctta gctttaaaag
    10621 gaactagtat gtcttttgta agtcccatat ctataaaagt accaatatcc gtgttatcaa
    10681 ctacttttag atacgtaaca tctccatttc taattatttc tatagtatta gaaaaataat
    10741 ttttaaatag tttgtaaaat attattgaat tttttctctc gaaatatata atttagaatc
    10801 ttctgattta tttttatgct cgatttcctt attttttttc ataaatatat atagaggagc
    10861 tattaacaac attgccccta atcctattaa aactctattt tgagttatag gttttgaaat
    10921 atcttctgcc caagcttgtt gtaacaacca taagctacct aaaatagcta ccattggtat
    10981 aacaggacca aatggaatct taaaagaggc cttaacatct gttctttttc ttaaaactat
    11041 tactgataaa caagttggta tgtactgagc aaatcttgca attacactca ttactgcaag
    11101 ttgttcaaaa cttccagtta gcacaagtgg tatacaacaa attaaagata ttattattgc
    11161 tacatatgga gcaccatatt tatttgtttt tcctataaat gcaggaagag aaccttcttc
    11221 tgctagagaa gaaccacatt taggagttac tattgatgaa cctatattta taccaaatat
    11281 agatattaat gttgctacag atatgaaaaa tttaccataa ttgcctaaaa atacacttga
    11341 agcatctgca attggaatac tgttttcaaa tagtctatct ccaagtatac ccatacagac
    11401 aatttgaatt aatatataaa ttattgcaca tataaatatt gtggttatta atgcgactgg
    11461 aagatttttt ttaggatttt ccatttctcc acttgccaca ataaatgatt caaagccggt
    11521 aaatgcgtaa aatactaata taatggctgg acccatacta gagttaacta catttcctga
    11581 aggaacaata tttacaaatt ttataaagaa tattccaact attataaaaa ctattaatgg
    11641 tactaattta gctatagtta ttacattatt cattatcttt gtgcttttaa ttccaaataa
    11701 gctatttatt gaaagtagtg ttacgagtat tgcagctata taacctttgt attcagtggc
    11761 agattctggc caaaatgaac ctaaagctgt tgcaaatcct actgctagag tagaccatga
    11821 tataattcta ataacccaag acattgtacc aacttcaaat cctataaaat ctccaaaagc
    11881 ttttttggag tatagatatg ctcctccatt cttatcaaac atgcttccaa cttctgcaaa
    11941 acataaaagt attgatagaa ctaagagtgt agcaaaaatg tatataaaca tactgttttg
    12001 acctgctaga ttataaactt tacctggtag taagaatata cctgaaccta ttatgctatt
    12061 aatccctaat aatatcatac taaatagacc taatttctta gctttttcca tattaattta
    12121 tctcctattc ttttattaat tactgtacta attaaaatac aaagtattca ttacatgcat
    12181 cataacacct attggtaaac aatcttcatc tatattaaag ctagaggtat gaagaggtga
    12241 aattaagccc ttttcctcat ttttacatcc taaatggaag aatgctcctt tacaatgttc
    12301 tgtgtaaaaa gaaaagtctt caccacctaa agacgggttt ggtctcaata taaatttttc
    12361 ctctccaagt aattctttag tatttgatat aactgtatct actaattctt tttcatttat
    12421 aacagcagga tagttttcat cacttacatg taaagtccca acacaaccaa atgcagatgc
    12481 agtgtctcca acaattttag ctattttatc aatcataaag tttcttgttt tgctatttaa
    12541 ggttcttaaa gtgccttcta gttttacatc ttcacatatt acattgtgtg catcaccacc
    12601 atatatttta cctatagtca aaacagcagc attatttggt tctaagtttc tacttattat
    12661 agtttgtaat gatgtaacaa tttgtgaagc tgtaactatt gcatcaatac cattttcagg
    12721 atatgcacca tgagctcttt tacctttgat acttattttt atagtgtcta cactagcatt
    12781 taatgtatca tattttattt cgataaatcc tgtttcgata tgtggcataa catgaagtcc
    12841 gaatatataa tcgaccttag gattttctaa acatccatct tcaactaaga attttgctcc
    12901 tccaaaacct tcttctgctg gttgaaataa gaattttaca tttacattaa gtttatcttt
    12961 tattgaatgt aaaactttac atgctccaag tagcatggtt gtatgtgcat catggccaca
    13021 agcatgcatt tttccagaat gtattgattt ataaggtatg ttgttttctt cttcaatagg
    13081 aagagcatcc atatctgctc ttatacaaat cgttttatct gcactttctt ttaaaatata
    13141 tgccataatt ccattgtgtt ttgtaaattc catataatca attccgattt cttttaaata
    13201 agaaattacc ttctgtttag taagattttc ttcaagagct aattctggaa ttttatgtaa
    13261 ttctcttctt atgtttataa gccatggttt tatagaatta caactttcta ttacaaaatc
    13321 ttttcctaat tctttggttt gatattttaa tttcaaagcc tgttgcattt ttattcctcc
    13381 aattgctttt tattgtttta ttaatataat aagcaattat tatgccataa ttttcgatgg
    13441 agaactttgt tttttataag aatattgaat aaatataatc atttatctat atgtatagta
    13501 taaaaaatga ttgcatagtt tcaattttca gtaaaaaata ttattttgaa gaaaatatat
    13561 tttatatgct agtttatata aa
//
LOCUS       DAYAOO010000103        13348 bp    DNA     linear   BCT 12-OCT-2024
DEFINITION  TPA_asm: Clostridioides difficile isolate ST8-SSI-h139-18
            SAMN40601845-rid21577343.denovo.104, whole genome shotgun sequence.
ACCESSION   DAYAOO010000103 DAYAOO010000000
VERSION     DAYAOO010000103.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN40601845
            Sequence Read Archive: SRR28438827
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 13348)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13348)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-MAY-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-MAY-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002157583.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002157583.1
            Genome Coverage       :: 163x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/11/2024 16:19:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 4,038
            CDSs (total)                      :: 3,963
            Genes (coding)                    :: 3,930
            CDSs (with protein)               :: 3,930
            Genes (RNA)                       :: 75
            rRNAs                             :: 6, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 60
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 33
            CDSs (without protein)            :: 33
            Pseudo Genes (ambiguous residues) :: 0 of 33
            Pseudo Genes (frameshifted)       :: 7 of 33
            Pseudo Genes (incomplete)         :: 25 of 33
            Pseudo Genes (internal stop)      :: 11 of 33
            Pseudo Genes (multiple problems)  :: 8 of 33
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13348
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN40601845-rid21577343.denovo.104"
                     /isolate="ST8-SSI-h139-18"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Denmark"
                     /collection_date="2018"
                     /collected_by="Statens Serum Institute"
     gene            98..1174
                     /locus_tag="ACGI5H_003337"
     CDS             98..1174
                     /locus_tag="ACGI5H_003337"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903275.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008233 - peptidase activity [Evidence
                     IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="M24 family metallopeptidase"
                     /protein_id="HFG9699026.1"
                     /translation="MKAQRLNAVLEQMKKDDISQMLVSDPTSIFYLTGVLIHPGERLL
                     ALYLNLNGNNKLFINELFPVSEDLGVEMVWFNDTQNPVEIITEHIDKNATMGVDKNWP
                     ARFLLNLIELGGGSKFVNSSYIIDTLRMCKDEEEKELMRIASKLNDKAMEQLKATVSG
                     ELTEKQLVGKLSKIYEDLGTDGFSFDPIIGFGPNGANPHGEPGNALVKPGDAIILDIG
                     CIKDNYCADMTRTVFYKEIPEKGREIFEIVLEANKRAEAIVKPGVRFCDIDAAARDYI
                     TEKGYGQYFTHRTGHSIGLEVHDKGDVSSINTDTVQPGMIFSIEPGIYLPGEFGVRIE
                     DLVLVTEDGCEILNKHDKEICVVG"
     gene            complement(1277..2119)
                     /locus_tag="ACGI5H_003338"
     CDS             complement(1277..2119)
                     /locus_tag="ACGI5H_003338"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003431496.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DegV family protein"
                     /protein_id="HFG9699027.1"
                     /translation="MDKIKLIVDSACDLPDDIIEKYNIEVVGLNVSFGEESYISGKEI
                     DNETFYRKMSESKVLPKTSCPSPDKFLEAYHCQEESVLVINISSGLSGTYNSALLAKD
                     MFEKEGNNKKVEVIDSLSGSIGIGQLVLKAAILIKEGKEIEEIVSIINKYKDNPPFFG
                     TLETLENAIKGGRINPIAGKIINTLNFKAIIQVADGVVTPIDKARGEGNSLKKLITLV
                     ESKIKDKEEKVLFIGHANCPEKAQKVREVMEKDVKYKDVVICEIGSVMGTYTSKGAIL
                     ITAI"
     gene            2303..2875
                     /locus_tag="ACGI5H_003339"
     CDS             2303..2875
                     /locus_tag="ACGI5H_003339"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454936.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HFG9699028.1"
                     /translation="MKTNNMKQAILSSATNLIAKNGVQNTSLADIAKDVNISKGTLYY
                     HYASKDDIIYDIADTHLEVITSAILNCVKNVKSKNSQIEMVNLILEKISTIESRGRVH
                     MYLICEAITSNNDLKERIRLKYIEWRTTLKSEIVESLEKYNSSENEQDAESFSFLLMS
                     IVDGLVVQSLLKTEKIPYENIASFLVNHWI"
     gene            complement(3038..3310)
                     /locus_tag="ACGI5H_003340"
     CDS             complement(3038..3310)
                     /locus_tag="ACGI5H_003340"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009906007.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9699029.1"
                     /translation="MLRERFVVRNHHNPHTSGCCGTGGEGCCGGDNHEHSHQHSHSHG
                     HEHEHVNGVGHDHNHDDGFSGTHEHSHEHTHTHGHEHSDGHTHEHK"
     gene            complement(3437..4309)
                     /locus_tag="ACGI5H_003341"
     CDS             complement(3437..4309)
                     /locus_tag="ACGI5H_003341"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426922.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HFG9699030.1"
                     /translation="MYGESKKLSIDNNIFLQYCLIILGMILSTLGINLYLAPAKLLSG
                     GVAGICVILYKLFGINQGISSFLMNIPIFIIARKYFDNKFLLISFVNMLLFSLALGLT
                     QDIAKYFPIDDTMLQCIYGGALTGIGMGLTFKARATAGGLDIIAAIMKRKYDIPMKNT
                     FLFINFFVVCAGAFLFGAKLVMYTLITMYIISFTMDIGKDCFDRKKSILLISNKYDEI
                     SKVIMNKMGRGVTFLEAEGAYTQNKKKMIYCIISANEIGKFKDLIYDMDSEAFISVNN
                     VEEVKGGGFKDKFL"
     gene            complement(4605..7712)
                     /gene="ileS"
                     /locus_tag="ACGI5H_003342"
     CDS             complement(4605..7712)
                     /gene="ileS"
                     /locus_tag="ACGI5H_003342"
                     /EC_number="6.1.1.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728473.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0004822 - isoleucine-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006428 - isoleucyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="isoleucine--tRNA ligase"
                     /protein_id="HFG9699031.1"
                     /translation="MAKFKPLVDSSVKQAEAQVFDYWKDINILEKTLEKGKDDPSFVF
                     YEGPPTANGNPGVHHVLSRTLKDSVCRYKTMSGYQVKRKAGWDTHGLPVEIQVEKELG
                     LTSKQQIEEYGIAEFNQKCRESVFSFEKQWRIMTERMAYEVDLDNPYITLDNNYIESV
                     WWILNKFNKEGYIYEGHKILPYCPRCGTGLASHEVAQGYKEVKTNTVIAKFKKKDADE
                     YFLAWTTTPWTLPSNVSLTVNADVDYLKVKKGDEVYYVSKPLADKVLGEDYEVLEEMK
                     GKDLEGLEYEQLMPFVEVDKKAFFITVGDYVTTEDGTGIVHTAPAFGEDDYNTGKRYD
                     LPVIQPVDETGKFTSTPWEGRFVMEDGLDVEIIKWLASENKLYSKEKVVHNYPHCWRC
                     QTPLVYYAKPSWYIEMTKLKDKLIENNNGVKWFPSFVGEKRFGNWLENLNDWAISRTR
                     YWGTPLPIWRCECGHTDSVGSRAELAEKAIEDVNPETVELHRPYVDDIHLKCEKCGKP
                     MTRVTEVIDCWFDSGAMPFAQHHYPFENKENFDQLFPADYISEGIDQTRGWFYSLLAV
                     STFVLGKAPYKSVLVPDLVLDKDGKKMSKSRGNTVNPMELFDQYGADALRWYLLYVSP
                     PWTPTKFDMDGLKEIQSKFIGTMKNVYNFFTLYANTDDINPTEFFVEYKDRPELDRWI
                     LSKFNNLMKDVEENLAIFELNKTLRMIQDFINDDLSNWYIRRSRRRFWATELTEDKKA
                     VYNTTYELLHGLCRAIAPFAPYMSEEMYRNLTGEVSVHLAEYPKCNEELVDTKLEEKM
                     DLAKNLVTLGRASREVERIKVRQPLQKVLVDGKFEDTISDVVDLIKEELNVKEVIFAK
                     DLDEYMNFSLKPNFKEAGPLLGSKMNLFVGALSKLNAHETANKLEKGETLTVDLDGEA
                     FEFNKDLVLIGITAKEGFNVSVENNLFVILDTKLTEELINEGYAREFISKVQQLRKSN
                     NFEVLDNIVIEYCGDDEIAKAVDHFNEYIKSETLALEINRVDDKSLEEQNLNDHMTGI
                     KVIKK"
     misc_binding    complement(7805..8037)
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            complement(8212..8739)
                     /locus_tag="ACGI5H_003343"
     CDS             complement(8212..8739)
                     /locus_tag="ACGI5H_003343"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416166.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DivIVA domain-containing protein"
                     /protein_id="HFG9699032.1"
                     /translation="MLTPIEIENKEFKKGLRGYRDEEVDEFLDIIKEDYESLCRENTA
                     LKEKLGLYQDQVNKYENIEETLKATLITAQSAAEDTCSAANKKAKIIVEEADLKARQI
                     IEQANNRVIEIRKEYDALVKEFKIFRNKFKSLLEDEIRSVDEIFYDVDEKCVNAFEGT
                     TVYNYSNDEAATTLE"
     gene            complement(8774..9559)
                     /locus_tag="ACGI5H_003344"
     CDS             complement(8774..9559)
                     /locus_tag="ACGI5H_003344"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897805.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlmH/Sll1252 family protein"
                     /protein_id="HFG9699033.1"
                     /translation="MDKLKLTNHIKDIDLKNKMFKVIDKANSCIKNYDVKSTEFLNPY
                     EVKNAVAILNSTNEIKYSVDGGYEQAERSTVFIYPFYMEYEDIEDTLRFLQIEGNFKF
                     KNISHKDYLGSILGLGIKREKIGDIIIHDSFCQVVVSSDICDFIIVNLEKVSRNNVIV
                     KEISRENIVNSSSKYKEVSFTVSSDRLDCVISGIYNISRQDSAKYINGEKVHVNYEKI
                     TSTSKIVKNDDLISIRGKGRAKVTQIGDITKKGKIKVQARLIV"
     gene            complement(9569..9826)
                     /locus_tag="ACGI5H_003345"
     CDS             complement(9569..9826)
                     /locus_tag="ACGI5H_003345"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YggT family protein"
                     /protein_id="HFG9699034.1"
                     /translation="MGTIRIALYYLLDIIAWMIVIKSLMTWFPNGRQSKIFDILENLT
                     EPIEGPIRSIMYKYTNGPIDFSPLIAIVLLMFLRQLVLVIF"
     gene            complement(9845..10303)
                     /locus_tag="ACGI5H_003346"
     CDS             complement(9845..10303)
                     /locus_tag="ACGI5H_003346"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897807.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein SepF"
                     /protein_id="HFG9699035.1"
                     /translation="MSNGIISKFKNWIVDEEEDYIEDEYESGMDDIVQEEEMNSGFST
                     AKANKIVNLHTTSQMKVVIVEPKVYDEAATIADHLKQRRAVIVNLEGLTNSEVRKSIF
                     NFMNGAVYVLDGSIQKVSKSIFILAPNNVDIDANMKKELESKAFFPWQNK"
     gene            complement(10343..11047)
                     /locus_tag="ACGI5H_003347"
     CDS             complement(10343..11047)
                     /locus_tag="ACGI5H_003347"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893687.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="YggS family pyridoxal phosphate-dependent
                     enzyme"
                     /protein_id="HFG9699036.1"
                     /translation="MGSIKDNLSEIRNKIDKAAKKVDRDSKEITLLAVTKTVDVDLVN
                     EAMREGITSVGENKPQELARKYDIIGDKLNWHLIGTLQTNKVKYIIDKVCMIHSLDRI
                     ALCEEIQKRAEQINREIDCLVQVNISKEESKHGLDREEVVDFVKEVSEKYKNIKIKGL
                     MTMAPFIEDEDEIRGVFKGLKDLSKQIKELNIPNVGMDVLSMGMSHDYEIAIEEGATI
                     VRVGTSIFGERNYNKK"
     gene            complement(11057..11692)
                     /locus_tag="ACGI5H_003348"
     CDS             complement(11057..11692)
                     /locus_tag="ACGI5H_003348"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897808.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HlyD family efflux transporter periplasmic
                     adaptor subunit"
                     /protein_id="HFG9699037.1"
                     /translation="MKKVKYTRLVILGILIYLVFNILVMIISKNVDTLVLKNEKVDAK
                     IHVKGTIEKDANDQSNYLSTYISKEDSNNFEKNQNVIIEYHEQKLDAKVYKIYENNNK
                     IMVKLKISNQIVANQDTSVEEFDIIYNQMECLKIPKTSIKTKDNKRGVYVIDEQSQSV
                     KFVILEGITYENESSVFVDYYKNDINGVTSVNLYDKIILRPNSINTNIRIK"
     gene            12073..13113
                     /locus_tag="ACGI5H_003349"
     CDS             12073..13113
                     /locus_tag="ACGI5H_003349"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426938.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HFG9699038.1"
                     /translation="MSEILLGTGLLLLVLCCFTIFSYKAPYGMKAMGALANAACATFL
                     VEAFNLSLLGDVLGMEFFRSVGAANGSLGGVAAAILVPLALGVSPVYAVLIGLSCLDF
                     SILSGFVAGYFVSFLIKFIEKKVPPGVDLVVVILLCAPLSRLIASNVDPLVNSTLLQI
                     GQVLIEATNISPIIMGIILGGLITVVGTSPLSSMALTSIIGLTGLPMAIGALGAFGSA
                     FMNSTLFAKLKLGSKKDIISVAIEPLTQSDIISANPIPIYSTNFFGGAFSGIIVALMG
                     LVNMTPGTATPVAGFAIMFAYNPVQQVLITAGLCALFNVIAGFLGSKIFSTFKVLTAG
                     EIRGTDVEEEIA"
BASE COUNT         4247 a         2256 c         1579 g         5266 t
ORIGIN      
        1 caaatttttt ttatatttct agaagaaaag tatactcttt tttgtttaat aatgctaaaa
       61 ttgatttgta ttgaattttg attaggagga aattattatg aaagctcaaa gattaaatgc
      121 tgtacttgaa caaatgaaaa aagatgatat ttctcaaatg ttagtaagtg accctacttc
      181 tatattttat cttacaggag tactaatcca tccaggcgaa agactattag cattatactt
      241 aaatttaaat ggcaataata aattatttat aaatgaatta ttcccagttt cagaagattt
      301 aggtgttgaa atggtttggt ttaatgatac tcaaaatcca gtagaaataa taactgaaca
      361 tatagacaaa aatgctacta tgggtgttga taaaaactgg ccagctagat tcttattaaa
      421 cttaatagaa ttaggtggag gaagtaagtt tgtaaattca tcttatataa tagatacttt
      481 aagaatgtgt aaagatgaag aagaaaaaga gttaatgaga atagcttcaa aattaaatga
      541 caaggctatg gaacaactta aagctactgt ttctggtgaa cttacagaaa aacaacttgt
      601 tggtaaatta tctaaaatat atgaagacct aggtactgat ggattttcat ttgaccctat
      661 tataggtttt ggacctaatg gagctaatcc acatggtgaa cctggaaatg cacttgtgaa
      721 accaggagat gcaataatct tagatatagg ttgtataaaa gataactatt gtgctgatat
      781 gacaagaact gtattctata aagaaatacc tgaaaaaggt agagaaatat ttgaaatagt
      841 tcttgaagct aataagagag ctgaagctat tgtaaaacca ggtgttagat tctgtgatat
      901 agatgctgct gctcgtgact acataactga aaagggatat ggacagtact tcactcatag
      961 aactggtcac tctataggac ttgaagttca tgataaagga gatgtatctt ctataaatac
     1021 agatactgta caaccaggaa tgatattctc tatagagcca ggtatatatt taccaggtga
     1081 gttcggagtt agaatagaag atttagtact tgttactgaa gatggttgtg agatattaaa
     1141 caaacatgac aaagaaatat gtgtagttgg ttaattctaa aatcaatttg ataaaattaa
     1201 aaagccatat aaaaatgttt taaacatttt tatatggctt taatttctca atctatgatt
     1261 tatttcaatc cattatttat attgcagtta ttaagattgc accctttgaa gtatatgtcc
     1321 ccatcactga accaatttca cagattacaa catctttgta ttttacatcc ttttccataa
     1381 cttcccttac cttttgagcc ttttctgggc aattagcatg tcctataaat aaaacctttt
     1441 cttctttatc tttaattttt gactctacta aagtaatcag ctttttcaaa ctgtttcctt
     1501 cacctcttgc cttatctata ggagttacaa cgccatctgc aacttgtatt atcgccttaa
     1561 aatttaaggt atttataatt tttcctgcta ttggatttat tctaccaccc ttaatagcat
     1621 tttctaaagt ttcaagtgtt ccaaaaaatg gaggattatc tttatattta tttattattg
     1681 aaacaatctc ttcaatttct tttccttctt ttattaatat tgctgctttt aacactaatt
     1741 gtcctattcc aattgaccca ctaagtgaat ctataacctc aactttcttg ttatttcctt
     1801 ccttttcaaa catatctttt gctaaaagtg cactattata agtcccagat aatcctgaac
     1861 ttatattaat cactaataca ctttcttcct gacaatggta tgcttctaaa aatttatcag
     1921 gagaaggaca tgatgttttt ggtagtactt tactctcact catttttcta tagaaagttt
     1981 cattatctat ttcctttcca gatatataac tttcttctcc aaaagataca tttaaaccaa
     2041 caacttctat gttgtatttt tctattatat catcaggtaa gtcacatgca ctgtccacta
     2101 tcaattttat tttatccata ttaacctcac tataagatat tattttattt attcagtcgg
     2161 tcgtacgacc gatttaatta ttattttata tattgaatga aaaaaagtca atagatatag
     2221 attctcgctt tattgacaat aaatatccat aagcttataa tgttattaat ttgttataaa
     2281 tatacatgga aaggtaggtt ttatgaaaac aaataatatg aaacaggcta ttttatcatc
     2341 tgcaaccaat ttaatagcca aaaatggagt tcaaaatact agccttgctg atattgcaaa
     2401 agatgtaaat ataagtaaag gtactttgta ttatcactac gcatctaaag atgatattat
     2461 atatgatatt gcggatactc atttagaagt tataactagt gctatactaa actgtgtaaa
     2521 aaatgtcaaa tcaaaaaatt ctcaaataga aatggttaac ttaatcttag agaaaatatc
     2581 tactatagaa agtcgtggta gggtacatat gtatcttatt tgtgaggcaa ttacttcaaa
     2641 taatgattta aaggaaagaa taagattaaa atatattgaa tggagaacta ctcttaaatc
     2701 tgaaattgtt gaatcactag aaaaatataa tagtagcgaa aatgaacagg atgctgaatc
     2761 attttctttt ttactcatgt caatagttga tggtttagtt gtccaaagtt tattaaaaac
     2821 agaaaaaata ccttatgaaa atatagcttc ttttttagtt aatcattgga tttaaactta
     2881 atacttagat aattaataaa agtgaactat ttaagttatc tactttaaca gttcactttc
     2941 ttatttattc tcaataattt ttacttaaaa cattcaattt ttatttaaac cttcatggaa
     3001 tcacaaaata aaaatctctt ataaatttaa aatgttttta tttatgttca tgtgtatgcc
     3061 catctgaatg ttcatgacca tgtgtatgtg tatgctcatg gctatgctca tgagtacctg
     3121 aaaaaccatc atcatgatta tggtcgtgac ctacaccatt tacatgctca tgttcatgcc
     3181 catgactgtg agaatgttga tgtgaatgtt catggttatc tcctccacag catccttctc
     3241 ctccagtccc acaacaccca cttgtatgtg gattatgatg atttcttact acaaatctct
     3301 ctcttaacat aattcttata cctcctagta tattattgag tacttcatgt accccattaa
     3361 ctacagtata catctaacta ggtataatct caatacatat ggcatttttt aacatatata
     3421 attaacatat ataatcttaa agaaatttat ccttaaaacc tccacctttt acttcttcaa
     3481 cgttattgac agaaataaaa gcttcactat ccatatcata aattaaatct ttaaatttac
     3541 ctatttcatt tgcagatatt atgcaataaa tcatcttttt cttattttgt gtatatgcac
     3601 cttctgcctc caaaaaagtg actcctctac ccattttatt cattatcact ttggatattt
     3661 catcatattt atttgatatt aaaagtatag atttttttct atcaaagcaa tcttttccta
     3721 tatccatagt aaaagaaatt atatacattg taattaaagt gtacatcacc aatttagctc
     3781 caaataaaaa agctcctgca catactacaa aaaaattaat aaataaaaat gtatttttca
     3841 taggtatatc atactttctt ttcattatgg ctgctattat atcaagtcct ccagcagtag
     3901 ctcttgcttt aaaagttaac cccataccta taccagttaa tgcaccacca taaatacact
     3961 gtagcatagt atcatctatt gggaaatatt tagcaatatc ttgtgttagc cccagtgcta
     4021 gagaaaatag taacatattg acaaaactta ttagcaaaaa tttattatca aaatactttc
     4081 tagctataat aaatattggt atgttcatca agaaacttga tattccctga ttaataccaa
     4141 ataatttgta taatataaca caaattccag ctactcctcc acttaataac ttggctggtg
     4201 ctagatataa atttattcct aaggttgata gaatcatacc caatataata agacaatatt
     4261 gtaaaaatat attattatca atacttagct ttttactttc accatacatc aaaacgcacc
     4321 cctttgcata ataaataaac caccctgcat aacacacgat aaatttacaa ataaatttat
     4381 cagaagtagt ttcctaaaaa tattattcat cctcacttaa acgtttattc attaatattc
     4441 tatcacatga cataaataat ttatatgatt tatatagatt tatttattgt aaattttgga
     4501 atattaaaac attttattga atagataatt atattacata aaaaatccct atagaaatct
     4561 ataaactaat ttctataggg attttggtta actaactatt atttttattt ttttataact
     4621 tttatacctg tcatatggtc atttaagttt tgttcctcta aagatttatc atctactctg
     4681 tttatttcta aagctaaagt ttcagacttg atatattcat taaaatggtc aacagcctta
     4741 gcaatttcat catcaccaca gtattctatt actatattat ctaatacttc aaagttatta
     4801 gattttctta attgctgtac tttagatata aattctctag cataaccttc attaattaac
     4861 tcttcagtta gcttagtatc tagtataaca aaaagattgt tttcaacaga tacattaaat
     4921 ccttccttag cagttatacc tattaatact aaatccttat taaattcaaa agcttcacca
     4981 tctaaatcaa ctgttaaagt ctcacctttt tcaagtttat tagcagtttc atgagcattt
     5041 aatttactta atgctccaac gaataaattc atcttagaac ctaataatgg ccctgcttcc
     5101 ttaaagtttg gttttaaact aaagttcata tactcatcta aatccttagc aaatattacc
     5161 tctttaacat taagctcttc ttttattaaa tcaactacat cacttattgt atcttcaaac
     5221 ttaccatcta ctaacacttt ttgtaatggt tgacgaactt ttattctttc tacttctctt
     5281 gaagctctac ctaaagtaac taagttttta gctaaatcca ttttttcttc taatttagta
     5341 tctactaact cttcattaca tttaggatat tcagctaaat gaacagatac ttctcctgtt
     5401 aagtttctat acatttcttc tgacatatat ggtgcaaatg gagctatagc tctacaaaga
     5461 ccatgtaaca attcataagt tgtattgtac actgcttttt tatcttctgt taattcagtt
     5521 gcccagaatc ttcttcttga acgtcttata taccagttag ataaatcatc atttataaaa
     5581 tcttgtatca ttcttaaagt tttatttaac tcaaatatag ctaaattttc ttctacatct
     5641 ttcattaaat tattgaactt agataatatc catctatcaa gttctggtct atctttatat
     5701 tctacaaaaa attcagttgg atttatatca tctgtgtttg catataaagt aaagaagtta
     5761 tatacattct tcatagtacc tataaattta ctttggattt cttttaatcc atccatatca
     5821 aatttagttg gagtccatgg tggagaaaca tatagtaaat accatcttaa tgcatctgct
     5881 ccatattggt caaataattc cattggattt actgtatttc ctcttgattt actcattttc
     5941 ttaccatctt tatcaagtac aagatctgga actaaaacac tcttatatgg tgcttttcct
     6001 aatacaaatg ttgatactgc aagtaatgag tagaaccaac ctctagtctg gtctatacct
     6061 tctgatatat agtcagctgg gaacaattgg tcaaagtttt ccttattttc aaatggatag
     6121 tggtgttgag caaatggcat agccccacta tcaaaccaac agtctataac ctctgttact
     6181 cttgtcattg gttttccaca tttttcacat tttaagtgta tatcatctac atatggtcta
     6241 tgaagttcaa ctgtttctgg atttacatct tctatagctt tttcagctaa ttcagctctt
     6301 gaaccaactg aatctgtatg accacattca catctccata taggaagtgg agttccccaa
     6361 tatctagttc ttgatattgc ccagtcattt agattttcta accagtttcc aaatctcttc
     6421 tctcctacaa aacttgggaa ccattttaca ccattattat tttctattaa tttatcttta
     6481 agtttagtca tctctatata ccagcttggt tttgcatagt atactaatgg agtttgacat
     6541 ctccagcagt gtggataatt atgaactact ttttctttgc tatataattt attttcagaa
     6601 gctagccatt ttattatttc aacatctagc ccatcttcca ttacaaatct accttcccaa
     6661 ggagtagatg taaatttacc agtttcatct actggttgaa taactggtaa atcatatctt
     6721 ttacctgtgt tgtagtcatc ttcaccaaat gctggtgctg tatgaactat accagttcca
     6781 tcttcagtag ttacataatc tcctactgta ataaaaaatg cttttttgtc aacttctaca
     6841 aaaggcatta attgttcata ttctaaacct tctaggtctt tacctttcat ttcttctaaa
     6901 acttcataat cttcacctag tactttatca gctaaaggtt tagatacata atatacctca
     6961 tcaccttttt taacttttaa ataatctaca tcagcattta ctgttaatga aacgtttgat
     7021 ggtaaagtcc atggagttgt tgtccatgct aagaagtatt catcagcatc ttttttctta
     7081 aatttagcta taactgtatt agtttttact tctttatatc cttgtgcaac ctcatgacta
     7141 gcaagaccag ttccacatct tgggcaataa ggaagtattt tatgtccttc atatatatat
     7201 ccttctttgt tgaatttgtt tagtatccac catacagact ctatatagtt attatctaaa
     7261 gttatatatg gattatctaa atcaacttca taagccattc tctcagtcat tattctccat
     7321 tgtttttcaa atgagaaaac tgactctcta catttttggt taaattcagc tattccatat
     7381 tcttctattt gttgcttgct agtaagacct aactctttct ctacttgtat ttcaactggt
     7441 aatccatgtg tatcccaacc agcttttctc tttacttgat aaccagacat tgttttatat
     7501 ctacaaactg aatctttaag cgttctagat aaaacatggt gtactccagg atttccatta
     7561 gctgttggag gtccttcata gaatacgaaa cttgggtcat ctttcccttt ttctaaagtt
     7621 ttttcaagta tatttatgtc tttccaataa tcaaaaactt gtgcttctgc ttgttttaca
     7681 gaactgtcta ccaatggctt aaatttcgcc atgtaaatca ccctttccta ctaaatatta
     7741 taattccaaa attttttatt ctttcacata aatttaaata ctaaaaaact cgcccccttt
     7801 aaaccaaagg gacgagttat aaatcgcgtt accaccctaa ttctatatgt aaactaaata
     7861 ctagctacat ataacactct aatagtataa cggtactaac cggcacagct tagtagaatt
     7921 taatcgttca gcctgcagct caagagtgat ttttatcttt ataaattcat tggttctcag
     7981 catacccaat tctctgtaaa attatctaaa gataaatgtc tctatcaacg cttttaaaaa
     8041 tttatctgtg tttatatgaa attctataac aaataatttg aatagtcaat atatttttga
     8101 aaaatataat aatttctatt tttcttacat ttttatccta tttttaatct ttgttataga
     8161 tttctcaaac tcacacaatt attctacata aaaaataaac aaattacaag cttattctaa
     8221 agttgtagca gcttcatcat tactataatt atacactgtt gttccttcaa atgcatttac
     8281 acatttttca tctacatcat aaaaaatctc atcaacactt cttatttcat cttctaacag
     8341 tgatttaaat ttatttctaa atatcttaaa ttctttgact aaagcatcat actcttttct
     8401 tatctctata acacggttat tagcttgttc tataatttgt ctagctttta aatcagcttc
     8461 ttcaacaatt atcttagcct ttttattagc cgcgctacaa gtgtcttctg ctgcactttg
     8521 agcagttatt aaagtagctt ttagtgtttc ttcaatattt tcatacttgt ttacttggtc
     8581 ttgatataac cctaattttt ctttaagagc tgtattttcc ctacatagag attcataatc
     8641 ttccttgatg atatctaaaa attcatcaac ctcttcatct ctataccctc ttaaaccttt
     8701 tttaaactct ttattttcta tctcaattgg agttagcatt acatttcctc ccagctataa
     8761 tttaaattag tccttataca attaatcttg cttgaacttt tatttttcct tttttagtaa
     8821 tatctcctat ttgtgttacc ttagctcttc ctttgcctct aatagaaatc aaatcatcgt
     8881 tttttactat tttagaagtt gaagttatct tttcataatt gacatggact ttttctccat
     8941 ttatgtattt tgcactatct tgtctagata tattgtaaat accacttatc acacaatcta
     9001 acctatctga agatactgta aatgatactt ctttatattt tgaagaacta ttaacaatat
     9061 tttctctgga aatttccttt acaattacat tatttcttga aaccttttct aagtttacaa
     9121 ttataaaatc gcaaatatca ctacttacaa ctacttgaca aaagctatca tgtataatta
     9181 tatctccaat tttttctctt tttataccta gacccagtat tgaccctaag taatctttat
     9241 gagatatatt tttaaatttg aaattccctt ctatttgtaa aaatctaaga gtatcttcta
     9301 tatcttcata ttccatgtaa aatggataaa taaatacagt gcttctttca gcttgttcat
     9361 aacctccatc cacactgtat tttatttcat ttgtagaatt taatattgct acagcatttt
     9421 tcacttcata tggattaaga aactccgtag acttaacatc atagtttttt atacaactat
     9481 tagccttgtc tatcacttta aacattttat ttttcaagtc tatatccttt atgtgatttg
     9541 ttagttttaa tttatccatc ctatcacctt agaatataac caatactaat tgtcttagga
     9601 acatcaataa tactattgca attaaaggag aaaaatctat aggtccattt gtatatttat
     9661 acattataga ccttattggc ccttctattg gctctgtaag attttccaaa atatcaaaaa
     9721 ttttactttg tcttccattt ggaaaccaag tcatcaagct ttttataact atcatccatg
     9781 ctattatatc taaaagataa taaagtgcaa ttcttattgt tcccatatat taaccgcctt
     9841 tttactattt attttgccaa gggaagaatg ctttactttc taattctttt ttcatatttg
     9901 catctatatc cacattatta ggagctagta taaatattga tttagaaacc ttttgtatac
     9961 ttccatctaa gacataaact gccccattca taaagttaaa tatagattta cgaacttcag
    10021 aattagtcaa tccttccaaa ttcactataa ctgcccttct ttgttttaga tggtctgcta
    10081 tagttgcagc ttcatcataa accttaggtt caactattac aactttcatt tggctagttg
    10141 tatgtaaatt tacaatttta tttgcttttg cagtactaaa gccactgttc atttcttctt
    10201 cttgaactat atcgtccatg ccactttcat attcatcttc aatgtaatct tcttcttcat
    10261 caactatcca attcttaaat ttagatatta ttccatttga cattattaac ttcctcctta
    10321 aaatttattc aaatttgagt aattattttt tattgtagtt tctttctcca aagattgatg
    10381 ttccaactct aacaatggta gccccttcct ctatagcaat ttcataatcg tgactcattc
    10441 ccattgacaa aacatccatc cctacattag ggatgtttag ttcttttatt tgttttgata
    10501 aatctttaag acctttaaat acacctctta tctcatcttc atcttctata aaaggtgcca
    10561 ttgtcattag accctttatt tttatatttt tatatttttc tgacacttct ttgacaaagt
    10621 ctacaacttc ttctctatca agtccatgct tagactcttc tttagatata ttcacttgta
    10681 ctaagcaatc tatttctctg tttatttgtt ctgcacgttt ttgaatttct tcgcataatg
    10741 caattctatc taaagagtgt atcatacaaa ctttatcgat tatgtactta actttattgg
    10801 tttgcaaagt tcctatcagg tgccagttta atttatcacc tataatatca tactttctag
    10861 ctaattcttg gggtttattt tcaccaacag aagtgattcc ttccctcatt gcctcattaa
    10921 ctaagtctac atcaacagtc tttgtgactg ccaaaagggt aatctctttg ctgtctctat
    10981 ctactttttt tgcagcttta tcaattttgt ttcttatctc agacaaatta tctttaatag
    11041 aacccattat tatcacctac tttatcctta tatttgtgtt tatactgtta ggtcttaaaa
    11101 ttattttgtc atatagatta acacttgtaa ctccatttat gtcattttta taataatcca
    11161 caaatacaga agattcattc tcataagtta ttccttctaa tatgacaaat tttacacttt
    11221 gtgattgttc atcaattaca tatacaccac gtttattgtc ttttgttttt atagaagttt
    11281 taggtatttt taaacattcc atctgattat atattatatc aaattcttcg acacttgtat
    11341 cctgatttgc aacaatttgg ttacttattt ttaattttac cattatttta ttattatttt
    11401 catatatttt gtaaactttt gcatctagtt tttgctcatg atattcaatt attacatttt
    11461 gatttttttc aaagttatta gaatcttctt tactgatgta tgtagataga taattacttt
    11521 ggtcattggc atctttttct atagttcctt ttacatgaat ctttgcatca actttttcat
    11581 tttttaacac caacgtatct acatttttgc taattatcat tactaatata ttaaatacta
    11641 aatatataag aataccaagt atcactaatc tggtatattt tacctttttc aaagactctc
    11701 cccctataaa attactttca ttataagtac ttcttctaaa aaatgtttat tcctttttta
    11761 taagataata ttttacgttc taataattat tttttccata ttaaatttat tttttatcaa
    11821 tcttcctata caagactgca ttatttatat ataattgtat tataaagtat aagtttaatt
    11881 tacattttat acgttaagct tactttatat atttttatag ttatttttat ttttagatgc
    11941 aatataaaac caattaagat ttaaaataac ttttgttatg ttgacattta tttaggtaat
    12001 catttatgaa ttaggataac gttatcacaa caaaagttta tgtcctaaaa aaaatacaag
    12061 gaggattttc ttatgtcaga aattttatta ggaacaggtt tacttttatt ggttctatgt
    12121 tgtttcacaa tttttagtta caaggcccca tatggtatga aggctatggg agctctagca
    12181 aacgctgcat gtgctacttt cttagtagag gcattcaacc tttctttact tggtgatgtt
    12241 ttaggtatgg aattttttag aagtgttgga gctgctaatg gtagtcttgg tggagttgct
    12301 gctgctatac ttgtgccttt agccttaggt gtatctccag tttatgcagt tttaatagga
    12361 ttatcttgtt tagatttttc tatattatct ggattcgttg ctggatactt tgtttctttc
    12421 ttaattaagt ttatagagaa aaaagtgcca cctggagtgg atttagtggt tgtaattctt
    12481 ctatgtgcac cactatctcg tcttatagca tcaaatgtag acccattagt taatagtaca
    12541 ctactacaaa ttgggcaagt tttgatagaa gctaccaaca ttagccctat aataatggga
    12601 attatactag gaggtctaat aacagtagtt ggaacgtctc cacttagttc aatggctctt
    12661 acatctataa ttggtcttac tggtcttcct atggcaatag gagcattagg tgcttttggt
    12721 tcagctttta tgaactcaac actatttgca aaattgaaat taggttctaa aaaagatatt
    12781 atatctgttg ctattgaacc attaacccaa tcagacataa tttcagctaa tccaatacct
    12841 atatattcta ctaatttctt tggaggagcc ttttctggta tcattgtagc cttgatgggt
    12901 cttgtaaaca tgacaccagg tacagctaca cctgtggctg gttttgctat aatgtttgct
    12961 tataatccag ttcaacaagt tcttataaca gctggtttat gtgctttatt caatgtaatt
    13021 gcaggatttt taggttcaaa aatattcagt acctttaaag ttcttactgc tggtgaaata
    13081 cgtggtactg atgtagaaga agaaattgct taaaaaacaa taagatttat aaatttatat
    13141 ctcaagtagt agagttttat attgtaggca attttattaa ttgcaaacgt tttatttttt
    13201 atttatgttt atgattatta tgtgtgttga atatttagat aaatttttat ttattatttt
    13261 tatttagatt tttgtttagt tttttatttg gttgatatat taggaataaa aattagtata
    13321 gtttattact agttagatgg cataactt
//
LOCUS       DAYAOO010000104        13315 bp    DNA     linear   BCT 12-OCT-2024
DEFINITION  TPA_asm: Clostridioides difficile isolate ST8-SSI-h139-18
            SAMN40601845-rid21577343.denovo.105, whole genome shotgun sequence.
ACCESSION   DAYAOO010000104 DAYAOO010000000
VERSION     DAYAOO010000104.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN40601845
            Sequence Read Archive: SRR28438827
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 13315)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13315)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-MAY-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-MAY-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002157583.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002157583.1
            Genome Coverage       :: 163x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/11/2024 16:19:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 4,038
            CDSs (total)                      :: 3,963
            Genes (coding)                    :: 3,930
            CDSs (with protein)               :: 3,930
            Genes (RNA)                       :: 75
            rRNAs                             :: 6, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 60
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 33
            CDSs (without protein)            :: 33
            Pseudo Genes (ambiguous residues) :: 0 of 33
            Pseudo Genes (frameshifted)       :: 7 of 33
            Pseudo Genes (incomplete)         :: 25 of 33
            Pseudo Genes (internal stop)      :: 11 of 33
            Pseudo Genes (multiple problems)  :: 8 of 33
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13315
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN40601845-rid21577343.denovo.105"
                     /isolate="ST8-SSI-h139-18"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Denmark"
                     /collection_date="2018"
                     /collected_by="Statens Serum Institute"
     gene            505..1407
                     /locus_tag="ACGI5H_003350"
     CDS             505..1407
                     /locus_tag="ACGI5H_003350"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905178.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HFG9699039.1"
                     /translation="MSGIISVMTQSLILSIMALGVYITYKILDFPDMSADGSYTMGAS
                     IVAFSLTNGISPVVATLMAILCGCTAGLVTGILHIKFKISNLLSGILVMGMLYSINLR
                     IMGKSNIPLFSFKHLFNGEISPIVLALAFVFICKVLLDLFLKTGLGYTLKGVGDNSQM
                     IKSLGINIGSIKILGLMISNGLIALSGGLMAQFLGFSDVNMGIGTLVLGIASIIIGIT
                     LFKKFTFIKDTTAIIVGSFIYQFTIYFAMSLGMLSTDLKLITAIVIIAFLATGNLNIS
                     LKKNKCKASTKNKSEKRGVVDVTN"
     gene            1394..2149
                     /locus_tag="ACGI5H_003351"
     CDS             1394..2149
                     /locus_tag="ACGI5H_003351"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892814.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HFG9699040.1"
                     /translation="MLQIKNLSKSFPNPYGEPNTIFENLSIDIEDGEFVSIIGSNGTG
                     KSTLLNIISGLIKESSGQITLDSTTITNLAEYKRTQIVSRVFQDPSLGTCPSMTVREN
                     LSLALNKGKLLNLKKCLRHKTNDLEHLLEGISLDLKKYLDIKVQYLSGGQRQSLSLIM
                     SSLASPKVLLLDEHTAALDPKTSNEVIELTDKIVREKNITTLMVTHNLKHALQYGDRL
                     IMLHKGEVVLDVKDKEKKDLTVEEILEKFEYAV"
     gene            2246..3283
                     /locus_tag="ACGI5H_003352"
     CDS             2246..3283
                     /locus_tag="ACGI5H_003352"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429748.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HFG9699041.1"
                     /translation="MIKSKKILSLIIAGVLGVSMLTGCSQNDGSNASNENKETDSKKQ
                     KNIGITQLVEHPSLDKAKKGFIKALEDKGYKDGDNIKIDFQNAQNDMPTTQSIASKFV
                     SDKKDLIYAISTPSAQAAYNATKDIPIIMTAVTDPVEAGLVKSLEKPGGNVSGTSDYL
                     SIDKTLELVKTLTPKAKKIGVIYNTSEVNSKIQVDSLHDYAKKNNYEVVEKGISSSSE
                     VNQAISSLVGKIDVLYVPTDNLIVSSMPIVSKVANENKIPIIASEEGSVSSGALACCG
                     IDYEKLGYKAGELAIEVLEGKSVGDIPVTTLDETEIIINEDTLKALDMQKLSADNIKY
                     IKSDENAKSTK"
     gene            4092..4994
                     /locus_tag="ACGI5H_003353"
     CDS             4092..4994
                     /locus_tag="ACGI5H_003353"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905178.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HFG9699042.1"
                     /translation="MSGIISVMTQSLILSIMALGVYITYKILDFPDMSADGSYTMGAS
                     IVAFSLTNGISPVVATLMAILCGCTAGLVTGILHIKFKISNLLSGILVMGMLYSINLR
                     IMGKSNIPLFSFKHLFNGEISPIVLALAFVFICKVLLDLFLKTGLGYTLKGVGDNSQM
                     IKSLGINIGSIKILGLMISNGLIALSGSLMAQFLGFSDVNMGIGTLVLGIASIIIGIT
                     LFKKFTFIKDTTAIIVGSFIYQFTIYFAMSLGMLSTDLKLITAIVIISFLATGNLNIS
                     LKKNKCKASTKNKSEKRGVVDVTN"
     gene            4981..5736
                     /locus_tag="ACGI5H_003354"
     CDS             4981..5736
                     /locus_tag="ACGI5H_003354"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892814.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HFG9699043.1"
                     /translation="MLQIKNLSKSFPNPYGEPNTIFENLSIDIEDGEFVSIIGSNGTG
                     KSTLLNIISGLIKESSGQVLLNKHNLSNLAEHRRTQIVSRVFQDPSLGTCPSMTVREN
                     LSLALNKGKLLNLRKCLRYKRDFLENLLEGVSLDLKKYLDVQVKFLSGGQRQSLSLIM
                     SCLTNPSVLLLDEHTAALDPKTSNEVIELTNKIVREKNITTLMVTHNLKHALHYGDRL
                     IMLHKGEVVLDVKGKEKEQLTVEEILEKFEYAV"
     gene            5867..6889
                     /locus_tag="ACGI5H_003355"
     CDS             5867..6889
                     /locus_tag="ACGI5H_003355"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860976.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CD0873 family tyrosine ABC transporter
                     substrate-binding lipoprotein"
                     /protein_id="HFG9699044.1"
                     /translation="MINKKRLASLILAGALSISMLTGCSQGGDSGNSKQESNSKGKEV
                     KKIGITQLVEHPALDATRTGFVKALEKNGFKDGENIDIDFQNAQNDMPTTQSIASKFA
                     SDKKDLIFAISTPSAQAAFNATKDIPILITAVSDPVAAGLVKTLEKPGTNVSGTSDFV
                     SVDKGLELLKIFAPKAKTIGVMYNTSEVNSKVQVDALKEYASKNGFKVVEKGITTSNE
                     VNQGISSLVGKIDVLYVPTDNLVASSMPIVSKIATENKIPVIAAESGPVEKGALACQG
                     INYEKLGYKTGEMAVKILNGESVSDMPVATSDDTDIIVNEDILKALGMEKPSNENISY
                     VKTKQE"
     gene            complement(7053..7610)
                     /locus_tag="ACGI5H_003356"
     CDS             complement(7053..7610)
                     /locus_tag="ACGI5H_003356"
                     /EC_number="2.3.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888695.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016407 - acetyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sugar O-acetyltransferase"
                     /protein_id="HFG9699045.1"
                     /translation="MTEKEKMLSGKGYYANDELLVKEREYCKKLTRLFNNTLEDEYEK
                     REDILRQLFGSVGKQINVEQNIRCDYGYNIHVGENFFANYDCIFLDVCKIEIGDNVML
                     APNVQIYTAYHPIDAQLRNSGIEYGSPIKIGDNVWIGGGVIITPGITIGDNVVIGAGS
                     VVTKDIPPNTVAVGNPCRVIKKIEE"
     gene            complement(7616..8692)
                     /locus_tag="ACGI5H_003357"
     CDS             complement(7616..8692)
                     /locus_tag="ACGI5H_003357"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004453580.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sulfate/molybdate ABC transporter ATP-binding
                     protein"
                     /protein_id="HFG9699046.1"
                     /translation="MSLYVDIEKDLSSFKLKVEIKQEKGTLGFLGESGSGKSMTLKCI
                     AGLEKPTRGKIVLNDRVLFDSEKKINLSTQDRKVGFLFQNYALFPHMTVSQNIELGLL
                     KLSKSEKKEIVARYLDILKLNGFEGRYPWQLSGGQQQRVALARALATSPDILLLDEPF
                     SALDHHLRSNMEKELMNMLKDYKGDILFVTHDIEEAYRVCDDIIVYNKGEGLPKRPKK
                     ELFESPKYLIEAKITGCKNISKLNRLDKNTIYATDWGCELTLNREIGDNIEYVGIREH
                     HIKVLDSNEDLNEKLCFELINIVENPFTYTIYVRKTDLSNECVPIQIELEKSKMRFKK
                     GDRIYLDFPQEYLFCFRYNYNKKE"
     gene            complement(8693..9376)
                     /gene="modB"
                     /locus_tag="ACGI5H_003358"
     CDS             complement(8693..9376)
                     /gene="modB"
                     /locus_tag="ACGI5H_003358"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905174.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0015412 - ABC-type molybdate transporter
                     activity [Evidence IEA];
                     GO_process: GO:0015689 - molybdate ion transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="molybdate ABC transporter permease subunit"
                     /protein_id="HFG9699047.1"
                     /translation="MGTDWSPLWISLKTSILSTIITFVIGIFVSYIMANYRGKWKGLI
                     DGLFTLPLILPPTVVGFFLLLLCGKNGFIGKFLLNFDRTLIFSWTATVISAVVVSFPM
                     MYRTSRSAFEQIDNNMLSAARTLGLNEWKVFFKIAVPLAWPGIIGGLVLSFARALGEF
                     GATLMIAGNIPGKTQTMPIAIFFAVEGGDMNKAMMWVMIIVAISIAMILLLNYWSEFQ
                     QKIIGKRCG"
     gene            complement(9525..10337)
                     /gene="modA"
                     /locus_tag="ACGI5H_003359"
     CDS             complement(9525..10337)
                     /gene="modA"
                     /locus_tag="ACGI5H_003359"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888684.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0030288 - outer membrane-bounded
                     periplasmic space [Evidence IEA];
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0015412 - ABC-type molybdate transporter
                     activity [Evidence IEA];
                     GO_function: GO:0030973 - molybdate ion binding [Evidence
                     IEA];
                     GO_process: GO:0015689 - molybdate ion transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="molybdate ABC transporter substrate-binding
                     protein"
                     /protein_id="HFG9699048.1"
                     /translation="MKKILGILGLVACLTLGTVGCNSNEDKKDDGKQEKTTKSSDSVE
                     LNISAAASLKEAMAKIEEEYKKVDSNVKLTVNYGASGSLQQQIEQGAPCDLFISAGQK
                     QMKALDEEKLLVSDTMKDLVKNDLVLISSADSSVSGMKDLTTDKVKKIAVGEAESVPA
                     GKYADEVLTNLNLKDKLKDKLVFAKDVKEVLAWVQSGNADVGFVYFSDTVNNDKIKVV
                     EKTDEKTHSPITYPVSVIKASKNVDAAKKFEEFLLSESGQKIFEEFGYKKVE"
     gene            10530..11459
                     /locus_tag="ACGI5H_003360"
     CDS             10530..11459
                     /locus_tag="ACGI5H_003360"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728716.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="substrate-binding domain-containing protein"
                     /protein_id="HFG9699049.1"
                     /translation="MDSLSSLTPVEVAELLKITKNTVYELIKRGELPSYKVGKKIRVD
                     TKDVEEYINSQKTGKVKDTHFNNKNIDINNNFKIIISGQDVILDILARSVEKKLDGIS
                     TFRSYIGSYNALYELYNGRVSIASSHLWDFETDEYNSTFVKKLLPGIPCVLINLAYRM
                     QGFYVAKGNPKEITTWEDLTKPSITIVNREKGSGTRVLLDGKLRLLNFNGKHIKGYDN
                     EELSHLGVASTVSRGIADVGLGNEKAALQVNNIDFIPLHKERYDLVIKKEDLQNPVYQ
                     TIINIINSPEFKAELQGLGGYDLTDTGKTIAKV"
     gene            complement(11620..12069)
                     /locus_tag="ACGI5H_003361"
     CDS             complement(11620..12069)
                     /locus_tag="ACGI5H_003361"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895896.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9699050.1"
                     /translation="MKNKNNKDKNMLNIKVLRVLGVLLILFDYTGDTLNFYNFFAKPL
                     VSGNLYKTTGTDCIVFLLFIVECVYLVGRYILKVKINWSEIIENEKGNFINNLLVEKI
                     QEESNIVYNLLNSYVLPNIYKKARGLMFKTYHMLIYIKEKYYYVNIY"
     gene            complement(12272..13252)
                     /locus_tag="ACGI5H_003362"
     CDS             complement(12272..13252)
                     /locus_tag="ACGI5H_003362"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454199.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HFG9699051.1"
                     /translation="MKNSFKNCISLRNKFIIISIVFLLILLIVSYIFGKLVYNSSVGL
                     EQLIKNEDIVKIFSERKDRPLEKLKNYKTSELMIQSSNNYKLESLFITSNIKTRDTMI
                     LVHGIGSSYYEMLKVAYRYLDKGYNVLVYNQRNTGNSGGDNYTFGLYERYDLDSLVKF
                     VKNKFPEGRLGVHGFSMGAGTAAMHSEINSKDDKVDFYILDSPYSEMKDAIRMGVLEK
                     RIPDILINYVVTCGDLYNKFKSGFWYSDVKPYESVEKSNVPILFIHGTKDTVCNYQNS
                     KKMYDLVKHDKKDLWLIEGIGHVDGFEHDSTVYFNKIFKFIDSNVLSDKS"
BASE COUNT         4692 a         2023 c         1753 g         4847 t
ORIGIN      
        1 aagaatataa ctatattcta catgtaaaaa tttttttatt taaactcaat tttctgataa
       61 tttgataatt tttcaaaatt tatagttgac ttttattttt tactgtatta aactaattac
      121 tatacaaaac agaaaacaaa attttcaaaa ttattaaatt aaaaggagag gtaaatatga
      181 agactttatt aaacaaacaa gtacgatttt ttagtagcca atttagttag ggtttgtacc
      241 taagttaaga caaattgtca taacatagat acaagcccct taggattatg atttttaagg
      301 attgtatcta tgttggctat agtaattgtt gttaaagttt ttattttatc atcataatat
      361 agagccacat ggattatact gtgtggctta ttcgaatttt tgccatacag ttatatatac
      421 tgtgtggttt ttttatatca aaatcatttt ttaaaaccaa attttaaaaa ccatttaaaa
      481 tattttcaaa ggggtgtttt atttatgtca ggtattatat ctgtaatgac gcaaagttta
      541 attttatcga ttatggcact gggggtttat ataacttaca aaatcttaga ttttccagat
      601 atgtctgctg atggtagcta tacaatgggt gcttctattg tagcattttc tcttactaat
      661 ggtatttctc ctgtagtagc aactttaatg gctatcttat gtggttgtac tgctggtctt
      721 gttacaggga ttcttcacat taagtttaag atatctaatt tactttctgg tattttagtt
      781 atgggaatgc tatactctat caatttaaga ataatgggaa aatcaaatat tcctctattt
      841 agctttaaac acttattcaa tggggaaata tctcctatag ttttagcctt agcttttgta
      901 ttcatctgta aagtcctttt agatttattc ctaaaaacag gtcttggata cactttaaaa
      961 ggtgttggtg ataactctca aatgattaaa tctctaggta taaatatagg ttctataaaa
     1021 atactaggac ttatgatttc aaatggactt atagctttat ctggtggtct tatggctcag
     1081 ttcttgggat tctcagatgt aaatatgggt ataggaactt tagttcttgg aattgcctct
     1141 atcataattg gtattacact atttaagaaa tttactttta tcaaagatac tactgcaata
     1201 attgttggct cttttatata ccaattcact atatactttg caatgagttt aggaatgtta
     1261 tcaactgact taaaactaat aactgccata gttataatag ctttcctagc tactggtaac
     1321 ttaaatattt cactaaaaaa aaacaaatgc aaagctagta ccaaaaataa atcagaaaaa
     1381 agaggtgttg tagatgttac aaattaaaaa tctttcaaag agtttcccta atccatatgg
     1441 tgaacctaat actatctttg aaaatttatc aatcgatata gaagatggtg aatttgtaag
     1501 tatcataggt agtaatggaa ctggtaaatc tactttatta aatataatat ctgggcttat
     1561 aaaagaatct tctggtcaaa ttactttaga tagtactact ataacaaatt tagctgagta
     1621 taaaagaact caaatagtaa gtagagtttt tcaagaccca agccttggaa cttgtccttc
     1681 tatgacggtt agagaaaatt tatctctagc acttaataaa gggaaattat tgaacttaaa
     1741 aaaatgtctt cgtcataaaa cgaatgactt ggaacactta cttgaaggaa tttctttgga
     1801 tttaaaaaaa tatttagata ttaaagtaca atatctttca gggggtcaaa gacaatcact
     1861 atcactaatt atgtctagct tagcaagtcc taaggtctta ttactagacg aacatacagc
     1921 agcacttgac ccaaaaacat caaatgaagt aatagagtta acagataaaa tcgtaagaga
     1981 gaaaaatata actacactta tggttactca caacttgaaa cacgctcttc aatatggaga
     2041 taggttgata atgcttcata agggtgaagt tgtattagat gtaaaagata aagaaaaaaa
     2101 agatttaaca gttgaagaaa tcttagaaaa atttgaatat gcagtataag aaattaaaat
     2161 cttagtttta atcagaaata tttataatct atcatatgaa tatatgaaca aatataatta
     2221 ttaaatttta agggaggaaa ataaaatgat aaaaagtaaa aaaatattaa gtttaattat
     2281 agcaggagta cttggtgtat caatgcttac tggatgttct caaaatgatg gctccaatgc
     2341 ttcaaatgaa aataaagaaa cagatagcaa aaaacaaaaa aatataggta ttactcaatt
     2401 agtggaacat ccatctctgg ataaagcaaa gaaaggattc atcaaagcac ttgaagataa
     2461 aggctataaa gatggagata atataaaaat agatttccaa aatgcacaaa atgatatgcc
     2521 tactacacaa agtattgcta gtaagtttgt atccgacaaa aaagatttga tatatgctat
     2581 atctactcca tctgcacaag cagcttataa tgctactaaa gatattccaa taataatgac
     2641 tgctgttaca gaccctgtag aagctggact tgttaaatct cttgaaaaac caggtggaaa
     2701 tgtttctggt acatctgatt atctttcaat tgataaaaca ttagaattgg ttaaaacatt
     2761 gactccaaaa gcaaagaaaa taggggttat atacaatact agtgaagtta attcaaaaat
     2821 ccaagttgat tctctacatg attatgctaa gaaaaataat tatgaagtag ttgaaaaagg
     2881 aatcagctct tcaagtgaag ttaaccaagc tatttctagt ttagttggta aaatagatgt
     2941 tttatatgtc cctactgaca atttaatagt ttcttctatg ccaatagttt ctaaagttgc
     3001 taatgaaaac aagattccta taatagcctc tgaagaaggt tctgtatctt ctggtgcttt
     3061 agcttgttgt ggaatagatt atgaaaaact aggttataag gctggagaac ttgctattga
     3121 agtattagaa ggaaaatctg ttggcgatat accagttact acattagatg aaactgaaat
     3181 aataattaac gaagatacac taaaagcact tgacatgcaa aagttatcag cagataatat
     3241 aaagtatata aagtcagatg aaaatgcaaa atctacaaaa taaaacttat taatttcaaa
     3301 aaataggtaa tatgaagtag gtaatatgaa aactttatat aataagtact cttatccacc
     3361 ctaacccttt gaaaattgtg cttattgtag caatttgaat attgcatata aagttattca
     3421 ttttccataa aagtcgtcta tattgacgac tgattatgaa agttatataa ctttctaatc
     3481 actacttgag ctgtccaaaa gaattttaat attctccaga cagctttttt ttatgatatt
     3541 tgattgatat acatgtctag ttattccata tttagtaaat attttgataa aatttccaca
     3601 ttcacttata acttaggata acgttttttt caaacaatac attaatttaa aagtattctg
     3661 agtatacatt atttagtatt ttaattaaat ttagcagttg acttttatta ttgtataatt
     3721 tataatttat aacaagtcga gaatacatat aattttctga ctaattaaaa tattaaaagg
     3781 gagagataat tatgaatact ttattaaaca atagaaaata ttattattat tatagccact
     3841 atttttaggg tttgtaccta cgttttaaca tagatacaga ccccttaaga ctactaaaat
     3901 tttgggattg tatctatgtt ggctatattg tttataaagt tttcatctaa ctatataaga
     3961 gccacataga ttaaactatg tggcttattc gtgtttttac cacatagttt tgtacactat
     4021 gtggtttttt tatacacaaa attagcaaat aattaaaatt ataaaaatat tttcaaagga
     4081 gtgttttatt tatgtcaggt attatatctg taatgacgca aagtttaatt ttatcgatta
     4141 tggcactggg ggtttatata acttacaaaa tcttagattt tccagatatg tctgctgatg
     4201 gtagctacac aatgggtgct tctattgtag cattttctct tactaatggt atttctcctg
     4261 tagtagcaac tttaatggct atcttatgtg gttgtactgc tggtcttgtt acagggattc
     4321 ttcacattaa gtttaagata tctaacttac tttctggtat tttagttatg ggaatgctat
     4381 actctatcaa tttaagaata atgggaaaat caaatattcc tctatttagc tttaaacact
     4441 tattcaatgg ggaaatatct cctatagttt tagccttagc ttttgtattc atctgtaaag
     4501 tccttttaga tttattccta aaaacaggtc ttggatacac tttaaaaggt gttggtgata
     4561 actctcaaat gattaaatcc ctaggtataa atatcggttc tataaaaata ctaggactta
     4621 tgatttcaaa cggacttata gctttatctg gtagtcttat ggctcagttc ttgggattct
     4681 cagatgtaaa tatgggtata ggaactttag ttcttggaat tgcctctatc ataattggta
     4741 ttacactatt taagaaattt acttttatca aagatactac tgcaataatt gttggctctt
     4801 ttatatacca attcactata tactttgcaa tgagtttagg aatgttatca actgacttaa
     4861 aactaataac tgccatagtt ataatatctt tcctagctac tggtaactta aatatttcac
     4921 taaaaaaaaa caaatgcaaa gctagtacca aaaataaatc agaaaaaaga ggtgttgtag
     4981 atgttacaaa ttaaaaatct ttcaaagagt ttccctaatc catatggtga acctaatact
     5041 atctttgaaa atttatcaat cgatatagaa gatggtgaat ttgtaagtat cataggtagt
     5101 aatggaactg gtaaatctac tttattaaat ataatatccg ggcttataaa agaatcttct
     5161 ggtcaagtat tattaaataa acataacttg tctaatttag ctgaacacag aagaactcaa
     5221 atagtaagta gagtttttca agacccaagt cttggaactt gcccttctat gactgttaga
     5281 gaaaacttgt ctttagctct taacaaagga aaactattaa atctaagaaa atgtcttcgt
     5341 tacaaaagag atttcttaga aaatttattg gaaggtgtat ctcttgattt aaaaaaatac
     5401 cttgatgttc aagtaaaatt tttatcagga ggtcaaagac aatcattatc actaattatg
     5461 tcgtgcttaa caaatccatc agttttatta cttgatgaac atacagcagc acttgaccca
     5521 aaaacatcaa atgaagtaat tgaattgact aataagattg taagggaaaa aaatataact
     5581 acacttatgg ttactcacaa cttaaaacac gctcttcatt atggtgatag attgataatg
     5641 cttcataagg gtgaagttgt attagatgta aaaggtaaag aaaaagaaca attaacagtt
     5701 gaagaaatct tagaaaaatt tgaatatgca gtttaaaata atatatctat tgtattaaac
     5761 tcggctttaa aataaagtta aaattacaat aattatggtt actttgtaat aattcatatg
     5821 aatatatgaa catatataac aataaatttt tgagggggat ataaaaatga ttaataaaaa
     5881 aagattggca agtttgattt tagctggtgc tcttagtata tctatgctta cagggtgttc
     5941 acaaggagga gactctggta attcaaaaca agaaagtaat tctaaaggta aagaagttaa
     6001 aaaaattggt ataactcaac tggttgaaca tccagcatta gatgccacta ggacaggttt
     6061 tgtaaaagca ttagaaaaga acggatttaa agatggagaa aatattgata tagacttcca
     6121 aaatgctcaa aatgacatgc ctactacaca aagtattgcg agtaaatttg catctgataa
     6181 gaaggactta atatttgcta tatctactcc atcagctcag gcagcattta atgctactaa
     6241 agatatacct atacttatta ctgctgtgag tgaccctgtt gctgctggat tagttaaaac
     6301 tcttgaaaag ccaggcacaa atgtatctgg aacatcagat tttgtttctg tagacaaagg
     6361 tttagaactt cttaaaatat ttgctcctaa ggcaaaaact ataggagtta tgtacaatac
     6421 tagtgaagta aattccaaag ttcaagttga tgctttaaaa gaatatgcat ctaaaaatgg
     6481 atttaaagtt gttgaaaaag gtataactac ttcaaatgaa gttaaccaag gtatttctag
     6541 tttagttggc aaaatagacg tattatatgt ccctacagat aacttagtgg cttcttctat
     6601 gcctatagtc tctaaaatag ctactgagaa taaaatacct gttatagcag ctgaatctgg
     6661 tccagttgaa aaaggtgctc ttgcttgtca aggtatcaac tacgaaaaac taggttacaa
     6721 aacaggtgaa atggcagtta aaattttaaa tggcgaatca gtatctgata tgcctgtggc
     6781 tacatcagat gatacagata tcattgttaa tgaagatata ttaaaagctt taggtatgga
     6841 aaaaccttct aatgaaaata tttcttatgt aaagactaaa caagaataga aagatatttt
     6901 ctatatacga ttaatatgcc tgtttctata aattaattta tagaaacagg catatatttt
     6961 tattttaatg tattatctat ttaaagatta tatgtaaatg ctcttaattt gtttgtataa
     7021 attttacttg tataaacttt atacaatcat atttattctt ctattttctt tattactcta
     7081 catggatttc caacagctac agtatttggt ggtatatctt ttgtgactac acttcctgca
     7141 cctattacta cattatcacc tatagtaatt cctggtgtta tgattactcc cccacctatc
     7201 catacattat cacctatttt tataggagaa ccatactcta tgcctgaatt tctaagttgt
     7261 gcatcaattg gatgataggc tgtatagatt tgaacgtttg gagctaacat tacattgtca
     7321 cctatttcaa ttttacatac atctaaaaaa atacaatcat aatttgcaaa gaaattttcg
     7381 cctacatgta tgttatatcc ataatcacac ctaatatttt gttctacatt tatttgcttg
     7441 ccaactgaac caaatagttg tcttaaaata tcttctcttt tttcatattc atcctctaaa
     7501 gtattattaa acaatctagt taatttttta caatactctc tttcttttac taacaattca
     7561 tcatttgcat agtatccttt cccagacaac attttttctt tttcagtcat atagtttact
     7621 cctttttgtt ataattgtat ctaaagcaaa ataaatattc ctgtggaaaa tctaaatata
     7681 ttctgtcacc tttcttaaat ctcattttac ttttttccaa ttctatttga ataggtacac
     7741 attcgttaga taaatcagtt tttctaacat atatagtata tgtaaaagga ttttctacaa
     7801 tgttaatcaa ttcgaaacat aacttttcat ttaaatcttc attagaatcc aagaccttaa
     7861 tatgatgctc cctgattccc acatattcta tattatcacc tatttctcta tttaatgtca
     7921 actcgcatcc ccagtctgta gcataaatag tatttttatc cagtctattt aatttggata
     7981 tatttttaca ccctgttatc ttagcttcta taaggtactt tggagattca aagagctctt
     8041 ttttaggtct ctttggaaga ccttctcctt tgttgtacac tataatatca tcacaaactc
     8101 ggtaagcttc ttcaatatca tgagtaacaa atagtatatc tcccttgtaa tcttttaaca
     8161 tattcataag ttctttttcc atattgcttc ttaaatgatg gtccaatgct gagaaaggtt
     8221 catctaaaag taatatatct ggagatgttg ccaatgctct agctagtgct accctttgtt
     8281 gttgaccacc agataattgc caagggtatc tcccctcaaa cccatttaat ttaagtatat
     8341 ctaagtacct tgctactatt tccttttttt cactcttact tagttttaaa agcccaagtt
     8401 ctatattttg acttacagtc atatgtggaa acaaagcata gttttgaaat aaaaatccta
     8461 cctttctatc ttgtgttgat aaatttatct tcttttcaga atcaaataga actctatcat
     8521 ttaatacaat tttacctctt gttggtttct caagccctgc tatacatttt aatgtcatac
     8581 tttttccaga accagattct cccaaaaacc ccagagtacc tttttcttgt ttaatttcta
     8641 cctttagttt aaaagaggat aaatcttttt caatatccac gtataagctc aactatccac
     8701 acctctttcc tataattttc tgctgaaatt ccgaccaata atttagtaat aaaatcattg
     8761 ctatagatat tgctacaata atcataaccc acatcatagc tttattcata tctccgcctt
     8821 caacagcaaa aaatatagct attggcatag tttgagtttt tccaggtata tttccagcta
     8881 tcataagtgt agcaccaaat tctccaagag ctctggcaaa cgacagcacc aatccaccaa
     8941 ttattccagg ccatgctaat ggaactgcaa tcttaaaaaa tactttccat tcattaagac
     9001 ctaatgttct agcagctgac aacatattat tatcaatctg ttcaaaagct gaccttgaag
     9061 ttctatacat cataggaaaa gacaccacta ctgctgaaat tacagttgct gtccaactaa
     9121 atattaaagt cctatcgaaa tttaataaaa actttcctat aaatccattc ttcccacata
     9181 gtaataataa aaagaaacct acaactgttg gtggcaaaat tagtggaagt gtaaatagtc
     9241 catctataag acccttccac ttacctctat agttagccat aatatatgac acaaatattc
     9301 ctattacaaa agttattatt gttgacaaaa tagatgtctt aagtgatatc cataagggtg
     9361 accaatctgt tcccatcttt ccctccttaa ttttaaatgg aaatagtgaa actaataact
     9421 ctattaattt cactatttcc attttattat aatacacaat tattttcaat tttcatttat
     9481 ttatatataa tttatactta attacacata atttatttct aagtttattc tactttttta
     9541 tatccaaatt cttcaaaaat cttttgtcct gactcactta ataaaaattc ttcaaatttc
     9601 ttagcagcat ctacgttttt actagcttta attactgaaa ctggatatgt aataggcgaa
     9661 tgagtttttt cgtctgtttt ttcaactact tttatcttat cattattgac agtatcactg
     9721 aagtaaacga atccaacatc agcatttcct gattgcaccc atgctaaaac ttcttttaca
     9781 tcttttgcaa atactagctt atcttttaac ttatctttta aatttaaatt agttaacacc
     9841 tcatctgcat acttaccagc tggaacactt tcagcttcac caacagcaat tttcttcact
     9901 ttatctgtag tcaaatcttt catacctgat acactactgt cagcagaaga aataagaact
     9961 aaatcatttt ttactaaatc tttcatagta tcagaaacta ataacttctc ttcatccaaa
    10021 gctttcattt gtttttgacc tgctgaaata aataaatcac aaggtgctcc ttgttctatt
    10081 tgttgttgta atgagcctga tgctccatag ttaactgtaa gttttacatt tgaatcaact
    10141 tttttatatt cttcttcaat ctttgccatt gcttctttta aacttgcagc agccgatata
    10201 tttaactcta ctgaatcact acttttagtt gttttttctt gttttccatc atcttttttg
    10261 tcttcattac tattgcaccc aactgtcccc aaagttaaac atgcaactaa tcctaatatt
    10321 cccaatattt ttttcataac aatctccctt tttgtaaatt tgatacacat tttaacatgt
    10381 tttattatgt tttatcatgt tttgttatat atagtttaat tatatataca tgataataaa
    10441 ttttcaagta atttatttac actactttta aatattttgc tacattttcc tttttttaat
    10501 gttaaaataa ccttatatgg aggtggatta tggactcatt atcatctttg acacctgtcg
    10561 aggtagctga attattaaag ataacaaaaa atactgtata tgaattaatc aaaagaggtg
    10621 aacttccttc ttataaagta gggaaaaaaa taagagttga tactaaagat gttgaagaat
    10681 atatcaacag ccaaaaaact ggtaaagtaa aggatacaca tttcaacaat aaaaatatag
    10741 atataaataa taatttcaaa attattattt ctggtcaaga tgtaatatta gacattttag
    10801 ctaggtctgt tgaaaaaaaa ttggatggaa taagtacatt tcgctcttat ataggtagtt
    10861 ataatgcttt gtatgagtta tataatggca gagtttctat agcatcatcc catctatggg
    10921 atttcgaaac ggatgaatat aatagcactt ttgttaaaaa gctattgcca ggaataccat
    10981 gtgtacttat aaatctagct tatagaatgc aaggtttcta tgttgctaaa ggaaatccta
    11041 aagagataac aacctgggag gatttaacaa aaccaagtat aaccattgta aatagggaaa
    11101 aaggttctgg aactagggtt ttactagatg gtaaacttag acttctaaac tttaatggta
    11161 aacatataaa aggttatgat aatgaagaat tatcacatct tggagttgca agtactgttt
    11221 ctcgtggaat agcagatgtt ggtttgggaa atgaaaaagc tgctttacaa gtaaataata
    11281 tcgactttat tcctcttcac aaagagcgct atgatttagt tattaaaaaa gaagacttac
    11341 aaaatccagt ttaccaaact ataattaaca taataaactc tcctgagttt aaagctgaac
    11401 ttcaaggtct tggcggatat gatttaactg atactggaaa aactatagca aaagtttaag
    11461 attaaaatcg caatctattt tataagattt ataatttttc acaaaattta taacttaaac
    11521 acgaaataaa ttgcgatttt agtgtctcaa aaaatttatg tctttcattt tatcatccaa
    11581 tacaaaatat aatataatta attgtgcaat catattatat taatatatat ttacataata
    11641 gtatttttct ttaatgtaga ttaacatatg atatgtttta aacatcaatc cccttgcttt
    11701 cttatatata tttggcaaca catatgagtt taataaatta tatacaatgt tgctttcttc
    11761 ttgtattttt tcaaccaaca agttatttat aaaattacct ttctcatttt caataatctc
    11821 actccaattt atcttaactt ttaatatata tcttcccact aggtatacac actctacaat
    11881 aaataataaa aatacaatgc agtcagtacc tgttgtctta tataaattac ccgatactaa
    11941 tggctttgcg aagaaattat aaaaattcaa agtatcaccc gtataatcaa aaagtattaa
    12001 tagcactcct agaactctca atactttaat attcaacatg tttttatctt tattattttt
    12061 gtttttcata tatactacct ctcttttctt tagatttgat tgtaatctaa tactaactct
    12121 tttatttgag gtataaatga atttaattgg tagttatttt catttttact agaaattaat
    12181 tcacattact aaacaaaact tatatttaaa cataaaaata gcctatctat tttttaataa
    12241 atacaaaaat aaataagcta ctaatattca attaactttt atcacttaaa acattactat
    12301 ctataaattt aaatatttta ttgaagtata ctgtactatc atgttcaaat ccatcaacat
    12361 gaccaatacc ttctataagc cataggtctt ttttatcatg tttaactaaa tcatacattt
    12421 tcttgctatt ttgataatta caaacagtat cttttgttcc atgtataaac agtatgggta
    12481 cattagattt ctcaactgac tcatatggtt ttacatcact gtaccaaaat ccagatttaa
    12541 acttattata taaatctcca caagtcacca cataattgat taatatatct ggtattcgtt
    12601 tttctagtac tcccattcta attgcatctt tcatttcaga ataaggagaa tccagtatat
    12661 aaaaatcgac cttatcatct tttgaattta tctctgaatg catagcagct gtccctgccc
    12721 ccatggaaaa tccatgcact cctaatcttc cttcaggaaa tttatttttt acaaatttaa
    12781 ctagactatc taaatcatac ctttcataaa gaccaaatgt gtaattatct ccaccactat
    12841 taccagtatt tctttgatta taaactaata cgttataacc tttatctaaa tatctatatg
    12901 ctacctttaa catttcatag taactacttc caattccatg aacaagtatc atagtatctc
    12961 ttgtctttat atttgaagtt ataaaaagac tttcaagctt gtaattatta gaactttgta
    13021 tcattaattc agatgtcttg tagtttttta atttctccag tggtctatct tttctctcag
    13081 aaaatatttt tactatatct tcgtttttta ttaactgctc taaaccaact gaactattat
    13141 acactaattt gccaaatata taagatacaa ttaataggat taatagaaac acaattgata
    13201 taattataaa tttatttctt aaactaatac aatttttaaa actatttttc atatttattt
    13261 accatacaat tttcctatat tatattttct aagtaatagc ataattgatt atact
//
LOCUS       DAYAOO010000105        12557 bp    DNA     linear   BCT 12-OCT-2024
DEFINITION  TPA_asm: Clostridioides difficile isolate ST8-SSI-h139-18
            SAMN40601845-rid21577343.denovo.106, whole genome shotgun sequence.
ACCESSION   DAYAOO010000105 DAYAOO010000000
VERSION     DAYAOO010000105.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN40601845
            Sequence Read Archive: SRR28438827
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 12557)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12557)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-MAY-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-MAY-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002157583.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002157583.1
            Genome Coverage       :: 163x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/11/2024 16:19:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 4,038
            CDSs (total)                      :: 3,963
            Genes (coding)                    :: 3,930
            CDSs (with protein)               :: 3,930
            Genes (RNA)                       :: 75
            rRNAs                             :: 6, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 60
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 33
            CDSs (without protein)            :: 33
            Pseudo Genes (ambiguous residues) :: 0 of 33
            Pseudo Genes (frameshifted)       :: 7 of 33
            Pseudo Genes (incomplete)         :: 25 of 33
            Pseudo Genes (internal stop)      :: 11 of 33
            Pseudo Genes (multiple problems)  :: 8 of 33
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12557
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN40601845-rid21577343.denovo.106"
                     /isolate="ST8-SSI-h139-18"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Denmark"
                     /collection_date="2018"
                     /collected_by="Statens Serum Institute"
     gene            <1..866
                     /gene="nth"
                     /locus_tag="ACGI5H_003363"
     CDS             <1..866
                     /gene="nth"
                     /locus_tag="ACGI5H_003363"
                     /EC_number="4.2.99.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429658.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0140078 - class I DNA-(apurinic or
                     apyrimidinic site) endonuclease activity [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA]"
                     /codon_start=3
                     /transl_table=11
                     /product="endonuclease III"
                     /protein_id="HFG9699052.1"
                     /translation="KGIDKMIGKKDEIIDEKDIENFMDIEEDKKSIKVSKKSTKKGET
                     EKKTKKSSSNKATQKTSKETKSKSKIKNESANEKDVNKILDELEKLYPDAKCELNYGT
                     AFELLIATILSAQCTDVRVNKVTSELFKKYNTARDFANLSIEEISKEIKSCGLYKSKS
                     QKIKDTSEQLCELYDGEVPDSLEKLIKLPGVGRKTAGVVLSNAFNHPAIAVDTHVFRV
                     SNRIGIVDEPNPQKTEFALMEAIPKERWSHSHHVLIFHGRRMCKARNPECASCPIKED
                     CNYYKELNETK"
     gene            1060..1530
                     /gene="trmL"
                     /locus_tag="ACGI5H_003364"
     CDS             1060..1530
                     /gene="trmL"
                     /locus_tag="ACGI5H_003364"
                     /EC_number="2.1.1.207"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429657.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008175 - tRNA methyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0006400 - tRNA modification [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (uridine(34)/cytosine(34)/5-
                     carboxymethylaminomethyluridine(34)-2'-O)-
                     methyltransferase TrmL"
                     /protein_id="HFG9699053.1"
                     /translation="MSLNIVLVEPEIPQNTGNIIRTCAATGSTLHLVKPLGFSLDDKH
                     LKRCGLDYWDIADIQYYDSFEELQEKYPNSKYFFSTTKAKQSHSDVKYEENCFIVFGK
                     ETKGLPEPLLKANMDTCIRVPMLDVEKARSLNLSNSVAIVVYEALRQIGYPNMR"
     gene            1566..2414
                     /locus_tag="ACGI5H_003365"
     CDS             1566..2414
                     /locus_tag="ACGI5H_003365"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888355.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DegV family protein"
                     /protein_id="HFG9699054.1"
                     /translation="MKNLKIICDSLSDVPKDLLDKYDIDIVSLTVILEEREYKDRIDI
                     SGDEFYKRLREENVYPKTSQATYAQFKEIFEKYTNEDREILYIAGSATATGTYQSAVM
                     AKNDVDGKIYTYDSNLLCMGTGLLVIKAGELASEGKSVAEILPVLDELKEKAFVIFSV
                     DTLEYLQKGGRISSTKAAIGSILNIKPILEIRDGLVSQISQVRGKKNVISKMMELIKS
                     NCGDDLSDQIVYIGYSDDFKEKEQLSKVMQDELRPKEIRFFQIGVCIGAHAGPGVTGI
                     ICLKNK"
     gene            2702..3706
                     /locus_tag="ACGI5H_003366"
     CDS             2702..3706
                     /locus_tag="ACGI5H_003366"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860858.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="BMP family ABC transporter substrate-binding
                     protein"
                     /protein_id="HFG9699055.1"
                     /translation="MRFKRILILMLTVAMIAGMLVGCANNPSNNPSSSKDNKSDISDK
                     SNSKKSVSMILDIEGTNNEAMNNSALLALNNAQKKLNIDTNKVESDDSSTFSNSIDIL
                     CNDNYDLIIAVGARFAKPLEMVAKKYPKQQFAIIDYEYDKQPSNITSISYEDNKSGYL
                     AGLIAGKMTESDKVGFIGGTKSSSRDKFESGFREGVKFSNSSIKDISVEYADVFKDSK
                     SVESIAKKMMDNGVDIIFSTTEDDSKAVIDAVRAKNKKVIATNKDQHELAPENVISSI
                     VKDFENPTYNLIQSFVKGNYKGGKVIENTVKSGSTGLAQNSSQNIPPDVLEYVNKNNK
                     "
     gene            3832..4944
                     /locus_tag="ACGI5H_003367"
     CDS             3832..4944
                     /locus_tag="ACGI5H_003367"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="BMP family ABC transporter substrate-binding
                     protein"
                     /protein_id="HFG9699056.1"
                     /translation="MKIKRILMACFVVVFTIFILAICNFDFGFDKVNKNNSNIDSAKS
                     KQSESKSLLTSAEKDKSNSKSKNKEDDTEDDSYVRKTIGVLLDTENLNNESYNNNVLS
                     ALKRADEDFDVRIKLEKPKTSKSFKESIEKLHKYEPDFIIAVGARFAEPIKEAATKYP
                     KQQFAIVDYTYKVQPANVISVSFQDNVTGYLAGLIAGKMTDTGKVGFIGGVEGSSRDK
                     YESGFRKGLKTSNKDAELLVKYSNIFENPESARTIAKEMRDSDRDVVFSATEDDSKRA
                     IQVARENGGKVIAINKDQYDMAPDNVISSIIKDVEQPVYELIKNVAKDGFKGSKVMEF
                     KIKDGELGLTSKSSRNIPPDVLEYIKKEYNKVKDTY"
     gene            5434..6195
                     /locus_tag="ACGI5H_003368"
     CDS             5434..6195
                     /locus_tag="ACGI5H_003368"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417991.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF6873 family GME fold protein"
                     /protein_id="HFG9699057.1"
                     /translation="MEFTREPFILDDDLCLALVDKRISYLMENELKLRNIEIIKTIEC
                     KELYESIKYHPDICICNLGKGDIIVAPNVYNQYKELLSRYKFNIIKGEANLLNRYPYD
                     IPYNIAIVGDYAIHNFKYTDKAILDYIENNKLKKINIEQGYSKCSICIVDRTSIITSD
                     KGIWKSMKNTEIECLLIEKGHINLFEMNYGFIGGCTGLISKDKLAFCGDVKKHPDYER
                     IKSFVESKNKEIVTLSCENLLDIGSIVPLMTRKER"
     gene            6198..7016
                     /locus_tag="ACGI5H_003369"
     CDS             6198..7016
                     /locus_tag="ACGI5H_003369"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417993.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative sporulation protein YtxC"
                     /protein_id="HFG9699058.1"
                     /translation="MVEKDNISSMKFLRNNNVNDRLIYTNDIVEVVIDSAKQEVLNKK
                     ILNGTKAEQRALNIDEISTEITSMIISIMKEKLLKEYILKCYGRTYPEDKNNIYIYSL
                     NIFAKKEIFMRETVFTRVRNYIEENDFINVEGFIRFRMREFMKYISAIGDIAVEEYLI
                     KKDQDEFIRVLKYFIDTQEEKIDLLKVHIMEDNTFVLYDKNGNKIDSIDDEEIINMVI
                     RENLNYEDFLISTLLTLCPKKIEILDLLNNNCSKEIIDTVEAIFENKVSIIMEN"
     gene            7196..7798
                     /locus_tag="ACGI5H_003370"
     CDS             7196..7798
                     /locus_tag="ACGI5H_003370"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF445 family protein"
                     /protein_id="HFG9699059.1"
                     /translation="MDNLIRILILAVIGGFIGYVTNVVAIRLIFRPIEPIKIPILNIE
                     IVGLIPKRRAEIAANVGEIIQEEFLSMDEILANIITDEDKEEVVRYIKARVKIIIHEK
                     VSFIPSGIKNMIQDYLGEIIESEVKQSIDELSKNIINKANERIDIQKMVEDKINELDL
                     YELEEIIIRIAKKELKHIEFLGLVLGFLIGIAQGLITMFI"
     misc_binding    8410..8648
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            8712..10631
                     /gene="thrS"
                     /locus_tag="ACGI5H_003371"
     CDS             8712..10631
                     /gene="thrS"
                     /locus_tag="ACGI5H_003371"
                     /EC_number="6.1.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009904969.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0004829 - threonine-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006435 - threonyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="threonine--tRNA ligase"
                     /protein_id="HFG9699060.1"
                     /translation="MIKVALKDGSIKEFENAISVMDVAKSISEGLARNVVAASVNGEV
                     VGLDHIIDTDCDLNLFKFEDKEGKEVFRHTSAHILAQAIKRLYPEAKLAIGPSIENGF
                     YYDIDLDHRLVPEDLEKIEAEMKKIAKEDLKIERFELPRNEALELMKEQGEDYKVELI
                     SDLPESEIISFYKQGDFTDLCRGPHLPSTKKVKAVKLQSVAGAYWRGDENNKMLQRIY
                     GTSFEKNKDLEEYLHLLEEAKKRDHRKLGKELGLFMIPEEGPGFPMFLPKGMELKNEL
                     LKFWREIHRKAGYIEIESPIILNRKLWETSGHWYHYKENMYTVKIDDEDYAIKPMNCP
                     GGLIYYNSQLHSYRDFPMRVAELGRVHRHELSGALQGLMRVRAFTQDDSHIFMLPEQI
                     KDEIKGVANLIDGIYKTFGFEYNLELSTRPENSMGSDEEWEAAENGLREALEELGLPY
                     TINEGDGAFYGPKIDFHLKDCLGRTWQCGTIQLDMQLPRQFDNTYIGQDGEKHRPVMI
                     HRVAFGSIERFIGILIEHYAGKFPVWLSPTQVKILPISDKFMDYANEVKKELFDKGIR
                     VELDDRAEKIGFKIREAQLEKVPYMLIVGEKEVADNNVSVRSRDKGEIGSIKLDEFIA
                     SISKEIESRESIIQD"
     gene            11399..12490
                     /locus_tag="ACGI5H_003372"
     CDS             11399..12490
                     /locus_tag="ACGI5H_003372"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902002.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Rpn family recombination-promoting
                     nuclease/putative transposase"
                     /protein_id="HFG9699061.1"
                     /translation="MIEKVEEKSKIIKTSKEYKRTIIEEKDKEWTKKLNDILSRSSFS
                     NDELDKIKALIPKEILTNENVGEVVTEDGYAKPEYDEVFKSLFTLNNEYDLLVNFIND
                     ILKDAPYANRNIKPFTQIKRIIRVETDPTINYIGEKRPKLDILAEDEENNHINIEMQR
                     AFENDYLERAEYYLSRVHGRKLEEGKEYKEIGKTIGIHILNHVKYNHIEDYVNCLRLT
                     MDGHPDIYSSKTALYFIELPKIHKSDYIVNRIMLWGKLISNPSNLDVRVIAKNDSIIK
                     KALDRLKELGSNEEYLLNLKRGAYIMNKSRNFKEEIERETAIRVAKEKDYKIIIMLKK
                     NGFKLDDILNKFNDFDLSEDEIKEVYENN"
BASE COUNT         5116 a         1206 c         2275 g         3960 t
ORIGIN      
        1 aaaaaggaat agataaaatg attggtaaaa aagatgagat aattgatgag aaagatatag
       61 agaattttat ggatattgaa gaagataaaa aaagtatcaa agtaagtaaa aaaagtacta
      121 aaaaaggtga aacggagaaa aaaacaaaga agagcagttc taataaggct acacaaaaaa
      181 caagtaaaga aactaaaagt aagtctaaaa ttaaaaatga gtcagcaaat gaaaaagacg
      241 taaataagat tttagacgag ttagaaaaat tgtatccaga tgctaaatgt gagttaaatt
      301 atgggacagc ctttgaactt ttaatagcaa ctattttatc agcacaatgt actgatgtaa
      361 gagtgaataa agttacttca gagttgttta aaaagtacaa cacagctaga gactttgcta
      421 atttgagcat tgaagaaatt agtaaagaga taaagagttg tggtctttac aaaagcaagt
      481 ctcaaaaaat aaaggataca tctgaacagc tatgtgaatt atatgatggt gaagtacctg
      541 atagcttaga aaagcttata aaattacctg gtgttggaag aaaaacggca ggggttgtac
      601 ttagtaacgc ttttaatcat ccagcaatag ctgtagatac tcatgtattt agagttagca
      661 atagaatagg aatagtggac gagccaaatc ctcaaaaaac agaatttgca cttatggaag
      721 ctataccaaa agaaagatgg tcacactcac atcatgtatt aatttttcat ggaagaagaa
      781 tgtgtaaagc tagaaatcca gaatgtgcaa gttgcccaat aaaagaagat tgtaattatt
      841 ataaagaact taatgaaacg aaataacttt tagaaagtaa gttgtacaag agggattttc
      901 tgatataata atacttgtga aaatgttaga taaaaaacta ttatatacat gaaataaaaa
      961 ttattattaa cattatttta tataatagta taatattatt gttattctgt ttataaaata
     1021 aaatttgata aataaaagcg atacttaggg aggattaaaa tgtcattaaa tatagtatta
     1081 gtagaaccag aaatacctca aaatacagga aatataataa gaacctgtgc agcaacaggt
     1141 tcaactttac atttagtaaa accactgggt ttttcattgg atgataaaca cctaaaaaga
     1201 tgtgggcttg actattggga tatagctgat atacaatatt acgatagctt tgaagaatta
     1261 caagaaaagt atccaaatag taaatacttt ttttctacaa caaaggctaa acagtcacat
     1321 tcagatgtga aatatgaaga aaattgtttt atagtatttg ggaaagaaac aaagggatta
     1381 ccagaacctt tgttgaaagc aaatatggat acttgtatta gagtgcctat gttggatgtt
     1441 gaaaaagcta ggtcattaaa tttatcaaat tcagttgcta ttgtagtgta cgaggcttta
     1501 agacaaatag gatacccaaa tatgaggtag tttcaacaag cctaaatgag aaaggagcat
     1561 acttaatgaa aaatctaaag ataatctgtg acagtttatc ggacgtgcca aaagatttgt
     1621 tagataaata tgatatagat atagtttcat taacagttat actggaggaa agagaataca
     1681 aggatagaat tgatatatct ggagatgaat tttataaaag gcttagagaa gaaaatgtat
     1741 atccaaaaac ttctcaagct acttatgccc aatttaagga aatttttgag aaatatacaa
     1801 atgaggatag agagatactt tatatagcag ggtctgccac agctacaggt acgtatcaaa
     1861 gtgctgtaat ggcaaagaat gatgtagatg gtaaaatata tacatatgac tctaacttgc
     1921 tttgtatggg aactggttta cttgtaataa aagcaggaga acttgcaagt gaaggaaagt
     1981 ctgttgctga aatattgcct gttttggatg aattaaaaga gaaggctttt gttatatttt
     2041 cagtagatac attggaatat ttacaaaagg gaggtagaat atcatctact aaggcagcaa
     2101 taggaagtat attaaatata aaaccgattc ttgaaataag agatggatta gtttcgcaaa
     2161 tatctcaagt aagaggaaag aagaatgtaa tttctaagat gatggaattg ataaaatcaa
     2221 attgtggtga tgatttatca gaccaaattg tgtatatagg atatagtgat gattttaagg
     2281 aaaaagaaca attatctaag gttatgcaag atgaattaag acctaaagaa attagatttt
     2341 tccaaattgg tgtgtgtata ggtgcacatg ctggtcctgg tgttactggt atcatatgct
     2401 taaaaaataa ataatatatt tttggatgac attatttatt tttttattaa attaggatag
     2461 aatattaatt gttgagatgt taaattggat ttattttgga tgaaattaag tgttgatata
     2521 ttagatttag tttgtaggga agtgtgtaaa tagataagaa tctattgcac acttttttat
     2581 agtaagattt attaaaaaaa tttcaaaatg tacttgtaaa ttgtatataa aaaaattata
     2641 aataggatgt aaaagtaaat aggatataaa aatatcgtaa atgtatgagg agtgaaattt
     2701 aatgcgtttc aaaagaatat tgatattgat gttaactgta gcaatgatag ctggaatgtt
     2761 ggttgggtgt gctaataacc caagtaataa tcctagctct agcaaagata ataaaagtga
     2821 tataagcgat aaaagtaatt caaaaaaatc tgtatcaatg atactagata ttgaaggaac
     2881 aaataatgaa gctatgaata attcagcttt attagcatta aacaatgctc aaaagaaact
     2941 taatatagat acaaacaaag tggaatcaga tgattcctca actttttcta atagtataga
     3001 tattttatgt aatgacaatt acgatttaat tatagctgta ggagctagat ttgcaaaacc
     3061 attggagatg gtagccaaga aatatccaaa gcaacaattt gcaattatag actatgagta
     3121 tgacaagcaa ccttctaata taacttcaat ttcttatgaa gataataaat ctggatacct
     3181 agctggatta attgctggaa aaatgactga aagcgataag gttggtttta taggaggaac
     3241 aaagagttct agtagagata aatttgaatc aggttttaga gagggtgtta aattttctaa
     3301 tagtagtata aaggatattt cagttgagta tgcagatgtt tttaaagata gcaaatcagt
     3361 agaatctata gctaaaaaaa tgatggataa tggagtggat attatttttt ctactactga
     3421 agatgattca aaagctgtaa tagatgcagt aagggcaaaa aataaaaaag ttatagcaac
     3481 gaataaagac caacatgagt tagctccaga aaatgttata agttctattg taaaagattt
     3541 tgagaatcct acttataatc tgatacaaag ttttgtaaaa ggaaattata aaggcggaaa
     3601 ggttatagaa aacacagtta agtctggaag tactggactt gcccaaaata gttctcaaaa
     3661 tattcctcca gatgtgttag aatatgttaa taagaacaat aaataatcta ctataatatc
     3721 caagaatact tatgagttta gttatgaggt gaattggatg ttataataga catatataga
     3781 aagacatatg cagaggtagg tcagacctat ctaaatcagg gagtgaattt tgtgaaaata
     3841 aaaaggatat tgatggcttg ctttgtagta gtttttacaa tttttatatt agctatatgt
     3901 aattttgatt ttgggtttga taaagtaaat aagaataatt ctaatataga tagtgctaaa
     3961 tcgaaacaga gtgagtctaa aagtttgcta acttcagcag aaaaggataa atcaaatagt
     4021 aaaagtaaga ataaagaaga tgacacagaa gatgattcat atgtaagaaa aactattgga
     4081 gtattgttag ataccgaaaa cttaaataac gaatcatata ataacaatgt actatcagcc
     4141 ttaaaaaggg ctgacgaaga ttttgatgtt aggataaaac ttgaaaaacc aaagacttct
     4201 aaaagtttta aagagagtat agaaaaactg cataagtatg aaccagattt tataatagca
     4261 gttggagcca gatttgcaga gccaattaaa gaagctgcta ctaaatatcc caaacagcaa
     4321 tttgcaatag ttgactatac ttataaagtt cagccagcta atgtaatttc tgtatcattt
     4381 caagataatg ttactggata tttagcagga cttattgcag gtaaaatgac tgatactggg
     4441 aaagtcggtt ttataggagg agttgagggt tctagtagag ataagtatga atctggattt
     4501 agaaaggggc ttaaaacttc aaataaagat gctgagttac tagttaagta ttcaaatata
     4561 tttgaaaacc ctgaatcagc tagaactatt gcaaaggaaa tgagagattc tgatagagat
     4621 gttgtatttt cagctacaga agatgatagt aaaagagcta ttcaggtagc aagagaaaat
     4681 ggtggtaaag ttatagctat taataaagac caatacgata tggctccaga taatgtaata
     4741 agttcaatta taaaagatgt agaacaacct gtatatgaac tgataaagaa cgttgcaaaa
     4801 gatggtttta agggaagtaa agtaatggaa tttaaaataa aagatgggga acttggcttg
     4861 acttcaaaga gcagtagaaa tataccacca gatgttttgg aatacataaa aaaagagtat
     4921 aacaaagtga aagatacata ttaattattg atgtagaaga ttataaaaat atattgctta
     4981 agtttagatt agcaataaaa agatatattt attaaatttg tgctaactgt acaaaatata
     5041 ttgattaagt ttagattagt gataaaaaga tatatttatt aaatttgtgt taacagtatg
     5101 gaatatactg cttaagttta gattggtgat aaaaggatat atttattaaa tttagtctaa
     5161 ctgtacaaaa tatattgatt gagtttagat tagcaataaa aagatatatt tattaaattt
     5221 gtgctaactg tacggaatat actgcttaag tttagattag tgataaaaag atatatttat
     5281 taaatttgaa ccaactgtac aaagctatac taattaagct tagaataact atataaaatt
     5341 ataacaataa gtgtgtgggc agaaaaattc tgctacacac tttatttata ttcacataaa
     5401 aaatttatca aaaaaaagaa aaaggagtaa aaaatggaat ttacaagaga accatttata
     5461 ctagatgacg atttgtgtct agctttggtg gacaaaagaa ttagttatct aatggaaaat
     5521 gaattaaaat taagaaatat agagataata aaaacaatag aatgtaaaga attatatgaa
     5581 agcataaaat atcacccgga tatatgtatt tgtaatttag gaaaaggaga tataattgtt
     5641 gcgccgaatg tatataatca atacaaagag ttattaagta gatataaatt taatataatt
     5701 aagggagaag ctaatttatt aaatagatac ccttatgata taccttacaa tattgcgata
     5761 gttggtgact atgctataca caattttaag tatactgaca aagcaatatt agattatatt
     5821 gaaaataata aacttaaaaa gataaatata gagcagggct attctaaatg ctcaatctgt
     5881 atagtagata gaacgtctat aataacatca gataaaggta tttggaaaag tatgaagaat
     5941 acagaaatag agtgtttatt gatagaaaaa ggtcacataa atttatttga gatgaattat
     6001 ggatttatag gtggatgtac agggttgatt tctaaggata aactagcttt ttgtggagat
     6061 gttaaaaaac atcctgacta tgaacgtata aaaagttttg tagaaagtaa aaacaaggag
     6121 atagttacac ttagctgtga aaatttacta gatataggtt ctatagttcc tctcatgaca
     6181 agaaaggagc gataactttg gttgagaagg ataatatttc ttccatgaaa tttttgagga
     6241 ataataatgt aaacgataga ttaatatata cgaatgacat tgtagaagta gtgatagatt
     6301 ctgcaaagca agaagtgtta aataaaaaaa tacttaatgg tactaaagct gaacaaagag
     6361 ctttaaatat tgatgagata tcaacggaaa taactagtat gataataagt ataatgaaag
     6421 agaaactttt gaaagaatac attctaaaat gctatgggcg tacatatcct gaagataaaa
     6481 ataatatata catatattca ctgaacatat ttgctaaaaa agagattttt atgagagaaa
     6541 cagtatttac tagggtgaga aattatatag aagaaaatga ttttataaat gtagaaggtt
     6601 ttattagatt tagaatgaga gaatttatga aatatatttc tgctataggt gatattgcag
     6661 ttgaggagta tttaataaag aaagaccaag atgaatttat aagagtttta aaatacttta
     6721 tagatactca agaagaaaag attgatttgc ttaaagttca tataatggaa gataatacat
     6781 ttgttttata cgataaaaat ggaaataaga tagacagtat agatgatgaa gaaattataa
     6841 atatggtaat aagagaaaat ttaaattatg aggacttttt aataagtacc ttattaactc
     6901 tatgtcccaa aaaaatagaa atattggatt tgttaaataa taattgctca aaggaaatta
     6961 tagatactgt agaagcaatt tttgaaaata aagttagtat aattatggaa aactagaatc
     7021 taagcatata aaagctatcc atataaaatt aaaaaaattc tttttaaatc gacacaaaag
     7081 acttataatt gtatataaag ctatagtata actagagtta ttaagtataa agaatatcta
     7141 cttgattaat gcaatatagc tggcaaatat acaattgata aggagtaatt ttataatgga
     7201 taatttaatt aggatactga tattagctgt tattggtgga tttataggtt atgttacgaa
     7261 tgtagttgct ataagactga tatttagacc aatagagcct attaaaatac ctattttaaa
     7321 tatagaaata gtaggtctta taccaaagag aagagcagaa atagcagcaa atgtaggaga
     7381 aataattcaa gaagaatttc tttctatgga cgaaatactt gcaaatatca ttactgacga
     7441 agataaggaa gaagttgtaa gatacataaa agcaagggta aaaattataa tacatgagaa
     7501 agtttcattt atcccgagtg gtataaaaaa catgatacaa gattatctag gagagataat
     7561 tgagtctgaa gttaagcaaa gtatagatga attgagtaaa aatataataa ataaagcaaa
     7621 tgaacgtata gatatacaaa aaatggtcga agataagatt aatgaactag atttatatga
     7681 attggaagag ataataataa gaatagctaa gaaagaatta aaacatatag agtttttggg
     7741 gcttgtctta gggtttttaa taggtatagc tcaagggtta attactatgt ttatttaaat
     7801 atatgagaag tagcatttat ttaagtacta attatattta cctatttgag tgaattactt
     7861 attaataaca tttagatatt aattgtattt acctatttga gtaaattact tattaatagc
     7921 atttagatat taattgtatt tacctatttg agtgaattac ttattaatag tatttagata
     7981 ttaattgtat ttacctattt gagtgaatta cttattaata gcatttagat attaattgta
     8041 tttatttatt tgattgtgtt acttattaat agtatttaag tatttactgt actacttatt
     8101 aaccatatta agtattgatt gtatttaagt atacaaaacc taaaaagagt acaaaaatta
     8161 gaagttagtt ttaataaaaa ttagttttag tatttatcta gtcatatcta tcatgcatgt
     8221 ggatacgttt taaaaatttt aaatttatga aaatattata atataactat aaatcaagag
     8281 attaatttaa tataaaaata taagaatatt ggtttacagc tgattgagat gaaaaataat
     8341 gggtaattaa tatattacat taatgttgat tgatgtataa ctatctgtta taatgaaaat
     8401 atattaaaaa tcatagtgtt gaagaggaag agtagagtag aaaccattct cagagaattt
     8461 gggtctatgg ctgagagccc atgtaatagg tctatttgaa aactaccttg gagctgagct
     8521 tattagcagt atttgtattt atactatacg tgaaagtgct cgggtgacga ccttatagtc
     8581 atcaagaggg ttgtatatac ttgtatacgc caacttgggt ggaaccgcga attaatatcg
     8641 tcccaaacat atttggggcg attttttatt acaaaaaatc taaaaattat ttcaataagg
     8701 aggaaaaaac aatgattaaa gttgctttaa aagatggctc aataaaagaa tttgaaaatg
     8761 ctatttctgt tatggatgta gctaaatcca ttagtgaagg attagctaga aatgtggtag
     8821 cagcgtctgt gaacggagag gttgtaggtc tggaccacat tatagatact gattgtgact
     8881 tgaatttatt taagtttgaa gataaagaag gtaaggaagt ttttagacat acatcagcgc
     8941 atatattagc tcaagctata aaaagacttt acccagaagc aaagcttgct ataggaccaa
     9001 gtatagaaaa tggattctac tatgatatag atttagacca tagattagtt ccagaggacc
     9061 tagagaaaat agaagctgaa atgaaaaaaa tagctaaaga agatttaaaa atagaaagat
     9121 ttgaacttcc tagaaatgaa gctttagagc ttatgaaaga acaaggagaa gactataagg
     9181 tagaacttat ttctgattta cctgaaagtg aaataatatc tttctacaag caaggtgatt
     9241 ttactgattt atgtagagga ccacatttac catctactaa aaaggtaaaa gctgttaaat
     9301 tacaaagtgt agcaggtgca tattggcgtg gtgacgaaaa taataagatg cttcaaagaa
     9361 tatatggaac ttcttttgag aaaaacaaag acttagaaga gtacttacat ttactagaag
     9421 aagctaaaaa gagagaccac agaaaattag gtaaagaatt aggattattt atgatacctg
     9481 aagaaggtcc aggattccct atgtttttac caaaaggtat ggaacttaaa aatgaattat
     9541 taaaattctg gagagaaata cacagaaaag ctggatatat tgagatagaa tctccaatca
     9601 tattaaatag aaaattatgg gagacttcag gacactggta tcattacaaa gaaaatatgt
     9661 atacagttaa aatagatgat gaggattatg ctataaaacc tatgaactgt cctggtggat
     9721 taatttacta taactctcaa ctacattcat atagagattt cccaatgaga gttgcagagc
     9781 ttggtagagt tcatagacat gagttatctg gtgcattaca aggattaatg agagttagag
     9841 catttactca agacgattca catatattca tgttaccaga gcaaattaag gacgaaataa
     9901 aaggagtagc taacttaata gatggtatat acaaaacttt tggatttgaa tataatttag
     9961 aattatctac aagaccagag aactctatgg gaagcgacga agagtgggaa gcagcagaaa
    10021 atggattaag agaagcttta gaagagttag gtctaccata tactattaat gagggtgatg
    10081 gagcattcta tggtcctaag atagacttcc atctaaaaga ttgtttagga agaacttggc
    10141 aatgtggtac tatccaatta gatatgcagc ttccaagaca atttgataat acttatattg
    10201 gtcaagatgg tgaaaagcat agaccagtta tgattcatag ggttgctttt ggtagtatag
    10261 aaagatttat aggtatatta atagagcatt atgctggtaa attcccagtt tggttatctc
    10321 caactcaagt taagatactt cctatatctg ataaatttat ggattatgca aatgaagtta
    10381 agaaagagtt atttgataag ggtataagag ttgaattaga tgatagagct gaaaaaattg
    10441 gatttaagat aagagaagct cagcttgaaa aagtgccata catgttaata gtaggtgaaa
    10501 aagaagtagc tgataataat gtttctgtta gatcaagaga taaaggtgaa ataggtagta
    10561 ttaaattaga tgaatttata gctagtattt caaaagaaat tgaatcaaga gaaagtatta
    10621 ttcaagacta atatatatta tattagtagc taagatattg ttatataaga taagtttaat
    10681 caatatgttg atatgttgat gcatagtgat taaatttatg aaaagatgag tataattaga
    10741 ggtacagtta atcatatttt tatgattaat gtacctctag ttttttgtat ggtagattta
    10801 ttaataaata tatcatagaa gtgttttgaa catggaaata tttatgtgca ttctttaaat
    10861 aaaagtttat tttttgagtg ataattaagt gcttgttggt aaggttatgg ctgtaaaaat
    10921 cataacttta ttttcatatt tgttccattt tcataaaaat tattatccct ttaagaaaat
    10981 ttcttaatcc tcttgaaata tttccttttt agtctaaagt taaatttctt tcttcaaaat
    11041 gaatatttaa atgaactaaa atttaagtac attttctaat cttatgagtc tatttttcat
    11101 agataattgc cctataatag aagaatctat gttggtgcta tgtggtgaca ataacagcat
    11161 tgtcagtgat taattaatgc tttataaatg attaattagt gttttatgtt atttttggac
    11221 ttatcctcta tacatagatt aatttattta actttagata gagagagaat gtcaagtaca
    11281 tacacagaca ttagagttta agaaagtgtt tatggagcaa gaacttttaa aagaggtagt
    11341 gacttagttt aatttcaaga aatgataaat acaaaagagg aaaaagagag gtgttgaaat
    11401 gatagaaaaa gtagaagaaa aatctaagat tattaaaaca tcaaaagaat ataagcgaac
    11461 tataattgaa gaaaaagata aagaatggac caaaaaatta aatgatatac ttagtagaag
    11521 tagtttttct aatgatgaat tagataaaat caaggcatta attccaaaag agattttgac
    11581 taatgaaaat gttggagaag ttgtgactga agatggatat gctaagcctg agtatgatga
    11641 ggtatttaaa tcattgttca ctttaaataa tgaatatgat ttacttgtaa attttataaa
    11701 tgatattcta aaagatgctc catatgctaa caggaatatc aaaccgttca ctcaaataaa
    11761 gagaataatt agagttgaaa ctgatccaac aattaattac attggagaga aaagacctaa
    11821 acttgatatt ttggctgaag atgaagaaaa taatcatata aatattgaga tgcaaagagc
    11881 ttttgagaac gattatttgg aaagagctga atattatctt agtcgtgtac atggtagaaa
    11941 gttagaagaa ggtaaagagt ataaagaaat tggaaaaact attggaatac atatactaaa
    12001 tcatgtaaaa tataatcaca tagaagatta tgtaaattgc ctgagattaa caatggacgg
    12061 gcatccagat atttattcta gtaaaactgc attatatttt atagagcttc caaaaattca
    12121 taaatctgac tatatagtaa atagaattat gctatgggga aaacttatta gtaatccttc
    12181 taacttagat gtaagagtta tagctaagaa tgattctatt attaaaaaag cacttgatag
    12241 attaaaagaa ttaggtagca atgaagaata tttattaaat ctgaaaagag gtgcttatat
    12301 catgaataaa agtagaaatt ttaaagaaga gattgaaaga gagacagcaa ttagagttgc
    12361 aaaagaaaaa gattataaaa taattataat gttgaaaaaa aatggtttta aattagatga
    12421 catattaaat aaatttaatg attttgactt aagtgaagat gagataaaag aagtatatga
    12481 aaataattga tgataaataa aaagtgaact tatataagtt tgctgaatcg gagtctggaa
    12541 atatttatat gtatttt
//
LOCUS       DAYAOO010000106        12358 bp    DNA     linear   BCT 12-OCT-2024
DEFINITION  TPA_asm: Clostridioides difficile isolate ST8-SSI-h139-18
            SAMN40601845-rid21577343.denovo.107, whole genome shotgun sequence.
ACCESSION   DAYAOO010000106 DAYAOO010000000
VERSION     DAYAOO010000106.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN40601845
            Sequence Read Archive: SRR28438827
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 12358)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12358)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-MAY-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-MAY-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002157583.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002157583.1
            Genome Coverage       :: 163x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/11/2024 16:19:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 4,038
            CDSs (total)                      :: 3,963
            Genes (coding)                    :: 3,930
            CDSs (with protein)               :: 3,930
            Genes (RNA)                       :: 75
            rRNAs                             :: 6, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 60
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 33
            CDSs (without protein)            :: 33
            Pseudo Genes (ambiguous residues) :: 0 of 33
            Pseudo Genes (frameshifted)       :: 7 of 33
            Pseudo Genes (incomplete)         :: 25 of 33
            Pseudo Genes (internal stop)      :: 11 of 33
            Pseudo Genes (multiple problems)  :: 8 of 33
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12358
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN40601845-rid21577343.denovo.107"
                     /isolate="ST8-SSI-h139-18"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Denmark"
                     /collection_date="2018"
                     /collected_by="Statens Serum Institute"
     gene            152..847
                     /gene="cas6"
                     /locus_tag="ACGI5H_003373"
     CDS             152..847
                     /gene="cas6"
                     /locus_tag="ACGI5H_003373"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424506.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004521 - RNA endonuclease activity
                     [Evidence IEA];
                     GO_process: GO:0043571 - maintenance of CRISPR repeat
                     elements [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="CRISPR-associated endoribonuclease Cas6"
                     /protein_id="HFG9699062.1"
                     /translation="MIKCLEMSVKVYLLENISLDNTSKEIRKLIDDTLIIEEKYKEFH
                     NKAGFKNYSFNLLYPLEKDKVYKKDCIYTFIIRTVDSELGMYFMNNLKNQHSDKIKVI
                     TMSKKVIPKKHIESIYSVTPIIAKFEDGYWRSNKTVEDLEKRIRENLIKKYNEFTNSK
                     IDEDFELFQVIKFINRKPISTKYKNISLLGDKISFKVSENDMAQEIANFALGVGVGEI
                     NSRGFGFVNYRWL"
     gene            859..2598
                     /locus_tag="ACGI5H_003374"
     CDS             859..2598
                     /locus_tag="ACGI5H_003374"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424505.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CRISPR-associated protein Cse4"
                     /protein_id="HFG9699063.1"
                     /translation="MLKDCLEIFEKEYKSLGNRLITDSYVLSYGTYILVKNFSNIDIL
                     EVSKNNVDSTEDIYHKFCELDYLSKLVSIDKSVDSKKIIHSNNYLSFFVKKENLRPDK
                     NNNVKLTEEIIDNYYDALLNPRIKYKSDKRKKEIYDSIENKYGKVDENKLNKIRLWIK
                     TNIFDLVESVKKDKNYLKIFFDEKIELYNDENQKYLYPNIYNKNDFNVIIDGKNYGLP
                     NDNMQLNEKKPFLKLKTRIRNSTPYLISDDEVLLQKAFFDYLTNKAANGEEVIYISSE
                     KGIHRKTDIPNEFSGYILRIKKGKELEIHDFDTVVNLNTKIKRINVECIIPIEYERHN
                     LKPNLEIGYINNLIKLEKTIDTVFFNKFMCNSYFKEIKNINLSDLVLRDILIRHREGL
                     YTWFYKGRDSIVKQTFSNYSMGIIENSIKNNNYIRAKEQYNLRIAIINYFHGGSNMAD
                     KIKVISESLFEKINSIKTKCIQSDEEYYFAVGQLASYFISKNKSKNKNHSLINPILNA
                     QNRKKIMLEIEKLFKKYNYDISYDNNRRFKNLYSMIVGYEVEEKKVNRDLLIGGYLYY
                     NLIYTKSEENENE"
     gene            2591..3580
                     /locus_tag="ACGI5H_003375"
     CDS             2591..3580
                     /locus_tag="ACGI5H_003375"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006441123.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I CRISPR-associated protein Cas7"
                     /protein_id="HFG9699064.1"
                     /translation="MNRRVYGVLGIKSIMSNWNADFSGYPKTTSTGEVFGSDKALKFP
                     MKKMWENEGEKVLYVKSLKIDESKKGEIKIRPKSLKERYEELFDIEDLKLEKNQQKVL
                     ENLFKAIDVKNFGATFAEEGNNIGIMGAVQIGQGFNKYEDINVEEQQILSPFRDPKAK
                     DKKKSTNEEEKEDANSTTLGKKIVSDEAHYFYPFSINPKAYEVFVNMGVTDGYTKNDY
                     KKFKEAALVSATAFNTNSKLGCENEFALFVETDEELYLPDLAQYITFEKREKSKDLIC
                     INIIHLIAELKDDIKSVEIYYNPYKIEIKPFKDEILPKIDKVKFMNIFTRKEV"
     gene            3582..4322
                     /gene="cas5b"
                     /locus_tag="ACGI5H_003376"
     CDS             3582..4322
                     /gene="cas5b"
                     /locus_tag="ACGI5H_003376"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424503.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003674 - molecular_function [Evidence
                     IEA];
                     GO_process: GO:0043571 - maintenance of CRISPR repeat
                     elements [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type I-B CRISPR-associated protein Cas5b"
                     /protein_id="HFG9699065.1"
                     /translation="MEVLKFNLSGKTAFFKKPDVNSIIYFTYGNIHKIALMGILGACL
                     GLGGYNQQSKEDEYPEFYSLLKDIKMSIVPKHEFGYINKKVHIFNNSVGYASKEEGGN
                     LIIKEQWLENVSWDIYIQLEDSTTSRELKRRFLSNKFVYIPYLGKNDHIANISEIEII
                     TDFYKTEDINRVDSFFIREDFEFEKSYFDDNDDYKEPFKYQEKLPYRLHRMTNQYILE
                     TIIFTNMSVKLINKKEVYQVKGLNLIFI"
     gene            4346..6904
                     /locus_tag="ACGI5H_003377"
     CDS             4346..6904
                     /locus_tag="ACGI5H_003377"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424502.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CRISPR-associated helicase/endonuclease Cas3"
                     /protein_id="HFG9699066.1"
                     /translation="MYFKKVELFDISNNINNCKNIYAHINKDRKPETLKEHSDLSYSY
                     LMKLCVKKDLSSCLERIENKFFKKDSFLSKNFYREIILNMVYMHDIGKINSSFQFVKM
                     QNKNFKKISLRYTKHSFISSMLYFDYYFEKLKKYDFEEKKILSLFLMINTYTISKHHG
                     VLKSFKEFLFLFKDEFINIKENFKDLFKNNYNLELKSVPKTIEKMVRGVEAYLDDSHI
                     KDNLAIDLYIYSKLMFSIVTSCDFYATSEYNSGNSIDDFGTIDNYNKYYDVLKKSEIY
                     KGMKKYREYLNNNSECPYKENDINRLRTEMSIEAEDAITHNTRKRIFYLEAPTGSGKT
                     VTSINLALKSIELNQSLKKIFYIFPFNTLVEQTKDVFINEIFNSVKDIQKDVVVINSI
                     TPIQTEDKEEDNKNVEYCVTKQEIDYDKSLLNRQFLHYPIVLTTNIGFFNYLFGVSRE
                     ECFPLIHMINSVIILDEIQNYKNEIWKEIILFLEKYADILNIKFIIMSATLPRLNKLG
                     CNDDNFAYLVKNREKFFKNHLFKDRVNISFEMLNSEINDIEEISEKVIEEAEIYNKIL
                     IEFIKKSSALKFYKNIKEKLKYKLEDVFLLTGDDNKLERKKIINKIKDMNSVILVATQ
                     VVEAGVDIDMDLGFKDISTIDSDEQFLGRINRSCKKLNSKVYFFNLDDASKIYKKDVR
                     KERHLTLNEESNRKIILDKDFEKYYDKIIARIEENKHKHNDKNIEVFIKDIVGNLNFT
                     EVKKWMALIPDLKEYTIFLNTIVKDESGNMIVGSDVWYEYISLLKNDNVEYSEKRVKM
                     SEIMEKLDYFTYKVQKFDNSFNDLVGDIFYIDDGSKYFTEGKFDRSKFNQNEFL"
     repeat_region   7029..10029
                     /inference="COORDINATES: alignment:crt:1.2"
                     /inference="COORDINATES: alignment:pilercr:v1.02"
                     /rpt_family="CRISPR"
                     /rpt_type=direct
                     /rpt_unit_range=7094..7123
                     /rpt_unit_seq="gttaaacagtaacatgagatgtatttaaat"
     gene            10114..10608
                     /locus_tag="ACGI5H_003378"
     CDS             10114..10608
                     /locus_tag="ACGI5H_003378"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424500.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CRISPR-associated protein Cas4"
                     /protein_id="HFG9699067.1"
                     /translation="MKITGTLINYYFHCKRQCWLLGNRINLEENSEDVKIGRLLHELK
                     EEKTKYKEIAIENIKIDKLTREYLVEVKKSDADIEAVKWQVLLYLKKLKEKGIVRKGK
                     IEFIEKNKTNKKIVFVDLSEVSEEQLISIEREIVNLINSDKAPCPDLKKGCKKCAYYE
                     YCYI"
     gene            10634..11641
                     /gene="cas1b"
                     /locus_tag="ACGI5H_003379"
     CDS             10634..11641
                     /gene="cas1b"
                     /locus_tag="ACGI5H_003379"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424499.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004520 - DNA endonuclease activity
                     [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0043571 - maintenance of CRISPR repeat
                     elements [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type I-B CRISPR-associated endonuclease Cas1b"
                     /protein_id="HFG9699068.1"
                     /translation="MLILGKTKYITSMGELTRKDNSICFRKNGRNVYIPVENTSEIFC
                     LNEVSLNSKLLDFLSRANIVVHFFNYYGGYSGTFYPKEYLISGKVTVAQVKTFEDRRE
                     EIAKSIVNGIRINAINTLSHYYKHGNSEIQPLLSHLKKDSINKLEKSNNIKEILSVEG
                     DIWQTFYTSFKYILREEFIFNKRVKRPPDNPLNAMISFGNSILYAKTVTAIYNTHLNQ
                     SVSFLHEPSESRFSLSLDLSENFKHVITFKTIFDLVNNRKINIEKHFDKNLNYCVLND
                     EGKQIFINSLEERLESVKEHPKLKRKVSLKTCIKLDAYKMLKCIMEEKSFIPYNIKDG
                     L"
     gene            11852..12142
                     /gene="cas2"
                     /locus_tag="ACGI5H_003380"
     CDS             11852..12142
                     /gene="cas2"
                     /locus_tag="ACGI5H_003380"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424497.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004521 - RNA endonuclease activity
                     [Evidence IEA];
                     GO_process: GO:0043571 - maintenance of CRISPR repeat
                     elements [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="CRISPR-associated endonuclease Cas2"
                     /protein_id="HFG9699069.1"
                     /translation="MKKKNNLNYNYVFVVYDVGEKRVSKVFKVCKKYLSHFQKSVFRG
                     EITPSKIMSLKRDLENIIDKDNDFVCIIKLMNSNTFEEEILGNNSNCENMIL"
BASE COUNT         5306 a         1085 c         1885 g         4082 t
ORIGIN      
        1 ttttatttgt cgaataaaaa ataaaaaatt ttaaaggaaa aagttaaaaa ataaagaatt
       61 ttataactat aaattatatt ttagagttta ttgttattaa atagatgaaa aaatcctaat
      121 atggattatc agaaaatgag gaggttgtta attgataaaa tgtcttgaaa tgtctgtaaa
      181 agtgtatctt cttgaaaata tttctttaga taatacatca aaagaaatac gtaaattaat
      241 agatgataca ttaattatag aagaaaaata taaggaattt cataataaag ctggatttaa
      301 gaattattct tttaatttat tatacccatt agaaaaagat aaggtttata agaaggattg
      361 tatatatact tttattatta gaactgtaga tagtgaatta ggaatgtatt ttatgaataa
      421 tttaaaaaat cagcattctg ataaaataaa ggttattaca atgagtaaaa aagtgatccc
      481 taaaaaacat atagaaagta tttactctgt cactccaata atagctaaat ttgaggatgg
      541 gtattggaga agtaataaaa cagtagaaga tttagaaaaa agaatcagag aaaatttaat
      601 aaaaaaatat aatgaattta ctaacagtaa aatagatgaa gattttgaat tatttcaagt
      661 tattaaattt ataaatagga aacctatttc tactaaatat aagaatatat ctttacttgg
      721 tgataaaata agttttaaag tatcagaaaa tgatatggct caggaaattg caaattttgc
      781 acttggagtt ggagtcggag aaattaattc tcgtggattt ggttttgtaa actatagatg
      841 gttataggag gtgaaaactt gttaaaggat tgtttagaga tttttgaaaa agaatacaaa
      901 tctttaggaa atagattgat aactgatagc tatgtcctat cctatggaac atatatattg
      961 gtgaaaaatt tttcgaatat agatatatta gaagtttcta aaaataatgt ggatagtaca
     1021 gaagatatat accataaatt ttgtgaactg gattatttat caaaactggt gtctatagat
     1081 aaatcagttg attccaaaaa aataatacat agtaataatt atctttcatt ttttgtaaaa
     1141 aaggaaaact taagacctga taaaaataat aatgtaaaac ttacagaaga aattattgat
     1201 aattattatg atgctttgtt aaacccaaga attaaatata aatctgataa aagaaaaaaa
     1261 gaaatctatg attcaataga aaataaatat ggtaaagtgg atgaaaataa attaaataaa
     1321 ataagactat ggataaaaac aaatatattt gatttagttg aatctgttaa aaaagataaa
     1381 aattatttaa aaatattttt tgatgaaaaa atagagttat acaatgatga aaaccaaaaa
     1441 tatttatatc caaatatata taataaaaat gatttcaatg taattattga tggtaaaaac
     1501 tatgggttac caaacgataa tatgcaatta aatgaaaaaa agccattttt gaaattaaaa
     1561 acaagaatta gaaattcaac tccttatttg attagtgatg atgaagtttt gttacagaaa
     1621 gctttttttg attatctaac gaataaagca gcgaatggag aagaagtaat atatataagt
     1681 agcgaaaagg gaattcatag aaaaactgat ataccaaatg aatttagtgg ttatatactg
     1741 agaataaaaa agggtaaaga attagaaata catgattttg atactgtggt aaatttaaac
     1801 actaaaataa aaagaataaa tgtagaatgt ataataccaa tagaatatga aagacataat
     1861 ttaaaaccaa atttagagat aggatatatt aataatctta taaaattgga aaaaacgatt
     1921 gatactgtat tctttaataa atttatgtgc aatagttatt ttaaagaaat taaaaatata
     1981 aacttaagtg atttagttct aagggatata cttattagac atagagaagg tttatatacc
     2041 tggttttata aagggagaga tagtatagta aagcaaactt tttcaaacta ttctatgggt
     2101 ataattgaaa attctataaa aaacaataac tacataagag caaaggagca atataattta
     2161 agaatagcta taataaatta ttttcatgga ggaagtaata tggcagataa aataaaagtt
     2221 attagtgaat ctttatttga aaaaataaat tctataaaaa cgaaatgtat acaaagtgat
     2281 gaagaatatt attttgcagt tgggcaatta gcatcgtatt ttatatctaa aaataagtca
     2341 aaaaataaaa atcattctct gattaatcct atactaaatg cacaaaatag aaaaaaaatc
     2401 atgttagaga tagaaaaatt atttaaaaaa tataattatg atataagtta tgacaacaat
     2461 aggcgattta agaatctata ttctatgatt gtaggatatg aggtagaaga aaaaaaagtt
     2521 aatagagatt tattaattgg tggatatcta tattacaatt taatatacac aaaaagtgag
     2581 gagaatgaaa atgaatagaa gagtatatgg agtattaggt ataaaatcta taatgtcaaa
     2641 ctggaatgct gatttttctg gatatccaaa gacgacatca acaggagaag tttttgggag
     2701 tgataaagca cttaagtttc ccatgaaaaa aatgtgggaa aatgaaggtg aaaaagtttt
     2761 atatgttaaa tcattaaaaa tagatgaatc taagaaagga gaaataaaaa ttagaccaaa
     2821 atcattaaaa gagagatatg aagaattgtt tgatatagag gacctaaaac tagaaaagaa
     2881 tcaacaaaaa gtactggaaa atctatttaa agctattgat gttaaaaatt ttggtgcaac
     2941 atttgcagaa gaaggaaata atataggaat tatgggcgca gtacaaattg gacaaggatt
     3001 taataagtat gaagatatta atgttgaaga acaacaaata ttatccccat ttagggatcc
     3061 aaaagcaaaa gataagaaaa agtcaacaaa tgaagaagaa aaagaagatg caaattcaac
     3121 tacattagga aaaaaaatag taagtgatga ggctcattac ttttatccat tttcaataaa
     3181 tccaaaagct tatgaagttt ttgttaatat gggtgtgact gatggatata ctaaaaatga
     3241 ttataaaaaa tttaaagaag ctgctttagt aagtgcaact gcattcaata caaattcaaa
     3301 gcttggttgc gaaaatgaat ttgcattatt tgttgaaact gatgaagagt tatacctacc
     3361 agatttggca caatatataa cttttgaaaa gagagaaaaa tcaaaagatt taatttgtat
     3421 aaatataatt catcttatag cagaattaaa agatgatata aagagcgttg agatatatta
     3481 taacccatat aaaatagaaa taaagccttt taaagatgaa atattaccta agatagataa
     3541 agttaaattt atgaacatat ttacaagaaa agaggtataa tatggaggtt ttgaaattta
     3601 acttaagtgg aaaaactgct ttttttaaaa aaccagatgt aaatagcata atttatttta
     3661 cgtatggaaa catacataaa attgcactta tgggtatttt aggagcttgt ttaggacttg
     3721 gtggatataa tcaacagagt aaggaagatg agtatccaga attctactct ttacttaagg
     3781 atataaaaat gtcaatagtt ccaaagcatg aatttggata tataaataaa aaagtccata
     3841 tatttaataa ttctgtagga tatgcatcaa aagaagaagg tggaaattta ataataaaag
     3901 aacagtggct tgaaaatgtt agttgggata tatatataca attagaagat tcaactacaa
     3961 gtagagagct taaaagaaga tttttatcta ataaatttgt atatatacct tacttaggca
     4021 aaaacgatca tatagctaat ataagtgaaa tagagataat tactgatttt tacaaaacag
     4081 aagatattaa cagagtggac agtttcttta taagagagga ttttgagttt gaaaaatctt
     4141 attttgatga taatgatgat tataaagagc catttaaata tcaggaaaaa cttccttata
     4201 gactgcaccg aatgactaat caatatattt tggaaactat catatttact aatatgtcag
     4261 ttaaattgat taataaaaaa gaggtatatc aagtaaaggg tttaaattta atctttattt
     4321 aaatttatag gtttaggaga attatatgta ctttaaaaaa gttgagttgt ttgatataag
     4381 taataatata aataattgca aaaatattta tgctcatata aataaagaca ggaagccaga
     4441 aactttaaaa gaacattcag acttatcata ctcatatctt atgaaattat gtgtaaaaaa
     4501 agatttaagc tcttgcctag agagaataga gaataaattt tttaaaaaag attctttttt
     4561 aagtaagaat ttttatagag agattatctt gaatatggtt tatatgcatg atataggtaa
     4621 gattaattct tcatttcagt ttgtaaaaat gcaaaataaa aattttaaaa aaatttcact
     4681 tagatatact aaacattctt ttatctcttc aatgctatat tttgattact attttgaaaa
     4741 gcttaaaaaa tatgattttg aagaaaaaaa aatattgagt ttatttttga tgataaatac
     4801 atatacaata tcaaaacatc atggggttct gaagtcattt aaagaatttt tatttttatt
     4861 taaagatgag tttataaaca ttaaagaaaa ttttaaagat ttatttaaaa acaattataa
     4921 tttagagctt aaatcagttc ccaaaactat agaaaaaatg gtaagaggtg tagaagcgta
     4981 tttagatgat agccatataa aggataactt agctatagac ttatatatat attcaaaatt
     5041 gatgttttca attgttacat cttgtgattt ttatgctaca tcagaatata atagtggtaa
     5101 ttctatagat gattttggga caattgataa ttataataag tattatgatg tattaaaaaa
     5161 atctgaaata tataagggga tgaaaaaata tagggaatac ttaaataaca atagtgaatg
     5221 cccatataaa gagaatgata taaacagatt gagaacagaa atgagtatag aagctgaaga
     5281 tgcaattaca cataatacga gaaaaagaat attttattta gaagcaccaa ctggaagtgg
     5341 aaaaactgtt acatctataa atctagcact gaaatctata gagttaaatc aatctttaaa
     5401 aaagatattt tatatatttc catttaacac attagtagag caaacaaaag atgtatttat
     5461 aaatgaaata tttaattctg ttaaagacat acaaaaagat gttgtagtta taaattcaat
     5521 aacaccaata caaacagaag ataaagaaga agataataaa aatgttgaat attgtgttac
     5581 taaacaagaa attgattatg ataaatcatt gttaaataga caatttttac actatcctat
     5641 agtacttaca actaatatag gtttttttaa ctatttgttt ggtgtatcaa gagaagaatg
     5701 ttttccattg atacatatga taaatagtgt aattatatta gatgaaatac aaaattataa
     5761 aaatgagata tggaaagaaa ttattttgtt tttagaaaaa tatgcagata tattaaatat
     5821 aaaatttatt ataatgtctg caactttacc tagattaaat aaattaggat gtaatgatga
     5881 taattttgca tatctagtaa aaaacagaga aaaatttttt aaaaatcacc tttttaaaga
     5941 tagagtaaac ataagttttg agatgttaaa ttcagaaatt aatgatattg aagaaatatc
     6001 agaaaaggtt atagaagaag cagaaatata taataagata ctgatagagt ttataaagaa
     6061 atcatcagca ctaaaatttt ataaaaatat taaagaaaaa ttgaagtata agttagaaga
     6121 tgttttttta ttaacaggtg atgataataa attagaaaga aaaaaaataa taaataaaat
     6181 taaagatatg aactctgtaa ttttggttgc tacacaagtt gtagaggctg gagtagatat
     6241 agatatggat ttgggattta aagatatatc tacaattgat tctgatgaac aatttttggg
     6301 aagaataaat agatcttgta aaaaattaaa ttcaaaagta tactttttta atttagatga
     6361 tgcaagtaag atatataaga aagatgttag aaaagagaga catttaactc ttaatgagga
     6421 aagtaataga aaaattattt tagataaaga ctttgaaaag tattatgata aaataatagc
     6481 cagaatagaa gaaaataagc ataaacataa tgacaagaat atagaggttt ttataaaaga
     6541 tattgtggga aatttgaatt ttacagaggt aaaaaaatgg atggctttaa taccagattt
     6601 aaaagagtat acaatctttt taaatactat agttaaagat gaatctggaa atatgattgt
     6661 aggaagtgat gtatggtatg aatatatatc actactaaaa aatgataatg ttgagtattc
     6721 tgaaaagagg gtgaaaatgt ctgaaattat ggaaaaacta gattatttta cgtataaagt
     6781 tcagaaattt gataattcat ttaatgattt agttggagat attttttata ttgatgatgg
     6841 aagtaagtat tttacagagg gaaagtttga tagaagtaaa tttaatcaaa atgaatttct
     6901 ataatgtatt tagattatat agagaatatt tatcccaagt taattaatta gaattagttt
     6961 aaaactattg aaatatagat attttatagc ttatatattt tttctaggat tagctgggat
     7021 aaaaaatctg tatattagtg ttttcagtgt atttaagggg attatatttt taagaagtac
     7081 tgattttaaa gtggttaaac agtaacatga gatgtattta aatttttact acataattaa
     7141 atcgtagtca ataccgtaca ggttaaacag taacatgaga tgtatttaaa tctctgaata
     7201 gccaatcaac tttgctgcat tactcttgtt aaacagtaac atgagatgta tttaaatgat
     7261 aatagttata tatatttttt acaatatatt attgttaaac agtaacatga gatgtattta
     7321 aatttacttc tcctgttttg aaatctatat attcatcatg ttaaacagta acatgagatg
     7381 tatttaaata taatattgat acaaatattt tgggtaaatg gacttgttaa acagtaacat
     7441 gagatgtatt taaattcgat atggtaacaa atttataaaa gatatagaat gggttaaaca
     7501 gtaacatgag atgtatttaa ataaagaaaa acgaaattgg tgattttgaa gcaatgtgtt
     7561 aaacagtaac atgagatgta tttaaattag taactacaat gcttttcctt ttgaagatga
     7621 tatgttaaac agtaacatga gatgtattta aattaataat gcacctattt taacagtacc
     7681 tggtctaaag ttaaacagta acatgagatg tatttaaatt caagtctagg agacaacata
     7741 aatagtacag atgggttaaa cagtaacatg agatgtattt aaattagtaa aaccagatgg
     7801 aactgttgta ataccaccaa agttaaacag taacatgaga tgtatttaaa tttaaaaaca
     7861 tcttgaggaa tatctttaac agtaattgtt aaacagtaac atgagatgta tttaaatgca
     7921 ttttcaggtg catgataaat aggtaaatta gatgttaaac agtaacatga gatgtattta
     7981 aattttttgt aattagccag attatcaact cccaaaatag ttaaacagta acatgagatg
     8041 tatttaaatt aaatatcgtc cttcgtagtc aaagcaacac cagaaggtta aacagtaaca
     8101 tgagatgtat ttaaatcgta aacaaaattt atcaagagaa gaatttctaa ggttaaacag
     8161 taacatgaga tgtatttaaa tttatatttg ataagagtat caaatcgact taaaatagtt
     8221 aaacagtaac atgagatgta tttaaattca atcttaatac acagacattt ttaaaaacaa
     8281 aacgttaaac agtaacatga gatgtattta aataaataga caaatattga atagctctgt
     8341 cttcatcaag ttaaacagta acatgagatg tatttaaata tatttacaaa atctctaaca
     8401 tattttttaa cttctgttaa acagtaacat gagatgtatt taaattcttt taaagagtcc
     8461 tcgggagcct cgaaaacttc agttaaacag taacatgaga tgtatttaaa ttactcaaat
     8521 aaatttctaa tttgtttatc tactaacgtt aaacagtaac atgagatgta tttaaattag
     8581 aatttacaac aatataagcc tctttaacca taagttaaac agtaacatga gatgtattta
     8641 aatatgtttt tagtagtaca tttaataaaa ctttttaaag ttaaacagta acatgagatg
     8701 tatttaaatg aaggaaccgt accttgataa atcacgaccg tacccgttaa acagtaacat
     8761 gagatgtatt taaattgtat atttgatgtt gttatttctc ctgtgtataa tgttaaacag
     8821 taacatgaga tgtatttaaa tgaagttcca cccccaccac ccccactact ttgagaagtt
     8881 aaacagtaac atgagatgta tttaaatccc cttttgcatg gtactagaca cgcatatatg
     8941 gtggttaaac agtaacatga gatgtattta aatacgccta tatgcggagt aacagatttt
     9001 tgcctggatg gttaaacagt aacatgagat gtatttaaat actgttttgg gatagactgg
     9061 aattaaatgg tctgtgttaa acagtaacat gagatgtatt taaatttttg gaatgaagca
     9121 tcaacagata ataaagaaaa agttaaacag taacatgaga tgtatttaaa tcaaggaaac
     9181 aaaagagaag tgaaaagaaa tataatgtta aacagtaaca tgagatgtat ttaaataatc
     9241 ttttaaatgg aaattaagta ataaaagaga gggttaaaca gtaacatgag atgtatttaa
     9301 attcaattaa ataagcatta atcttagtaa aatcaaacgt taaacagtaa catgagatgt
     9361 atttaaattt tcttgtgtta attgaacccc cattttaagc tccagttaaa cagtaacatg
     9421 agatgtattt aaatcagaat acagcttcta tatctggata catttgtctt ggttaaacag
     9481 taacatgaga tgtatttaaa tgtgaaaagt aatacaggta tagagtctaa acgctcggtt
     9541 aaacagtaac atgagatgta tttaaatcaa tgtatcctct tttttagttt tggagcctct
     9601 tttgttaaac agtaacatga gatgtattta aattagttag cacattttat ttcaagcctt
     9661 aaaacattcg ttaaacagta acatgagatg tatttaaatt aatttgcaca cttaacctct
     9721 aatcttaaag tattagttaa acagtaacat gagatgtatt taaataacac aatattatct
     9781 ttaatagaat taaacaaatg agttaaacag taacatgaga tgtatttaaa tttttgttgg
     9841 tcttgtgctt cttttaaaag ctgattagtt aaacagtaac atgagatgta tttaaattta
     9901 aaaagttctg ttattaaaac atccaaacca atcgttaaac agtaacatga gatgtattta
     9961 aattctgtac catctagcca aaccgttttt gaagttaaag ttaaacagta acataagatg
    10021 tatctaaatt actctatcat aaaattttaa tatattaaac aaactaatat gtgatatact
    10081 tatgtataaa taacaaaata aataggtgat gttatgaaaa ttacaggaac tttgataaat
    10141 tactatttcc attgtaaaag acaatgctgg ttgcttggta atagaataaa tttggaagaa
    10201 aatagtgaag atgtaaaaat aggtagactt cttcatgaac taaaagaaga aaaaacaaaa
    10261 tataaagaaa ttgcaattga aaatataaaa atagacaaat taacaagaga atatttagta
    10321 gaggttaaaa agtctgatgc tgatatagaa gctgttaagt ggcaagttct tttatattta
    10381 aaaaagttaa aagaaaaggg aattgtaaga aaagggaaaa ttgaatttat agaaaaaaat
    10441 aaaactaata aaaaaatagt ctttgtagat ttgagtgaag tatctgaaga acagcttata
    10501 tctatagaaa gagaaattgt taatttaata aatagtgata aagcaccatg tcctgattta
    10561 aaaaaaggat gtaaaaaatg tgcctattat gaatattgtt atatataaag aggtataaga
    10621 aacatataag gaggtgttaa tattgggaaa gacaaaatat attacctcaa tgggtgaact
    10681 cacaagaaaa gataattcta tatgttttag aaaaaatgga aggaatgtat atataccagt
    10741 agaaaatact agtgaaatat tctgtctaaa tgaggtatct ttaaattcaa aattactgga
    10801 ttttttatca agagcaaata ttgttgttca tttttttaat tactatggtg gatatagtgg
    10861 aactttttat cctaaagaat atttaataag tggaaaagta acagtggcac aggtaaaaac
    10921 ctttgaagat agaagagaag aaatagcaaa atccatagtc aatggtataa ggattaatgc
    10981 aataaataca ttatcgcatt actataagca tggaaattca gaaatacaac cattattatc
    11041 acatctaaaa aaagattcta taaacaagtt agaaaaatca aataatataa aagaaatatt
    11101 atcagtcgaa ggagatattt ggcaaacatt ttatacttcc tttaagtata ttttaagaga
    11161 ggaatttatt tttaataaaa gagttaagag accaccagat aatcccttaa acgcaatgat
    11221 atcatttggt aacagtattt tatatgctaa aactgtaact gctatatata atacacatct
    11281 aaatcaaagt gtaagttttt tacatgaacc aagtgaaagt agattttctt taagtctaga
    11341 tttaagtgaa aattttaaac atgttataac ttttaaaact atatttgatt tagttaataa
    11401 tagaaaaata aatattgaaa aacattttga taaaaatttg aactactgtg ttctaaatga
    11461 tgaaggaaag caaattttta taaattcttt agaagaaaga ttagaatcag tcaaagaaca
    11521 tccaaaatta aaacgaaaag taagtttaaa aacctgtata aaattagatg cttacaaaat
    11581 gttaaagtgt ataatggaag aaaaaagttt tattccatat aacataaaag acggattata
    11641 atttaaacat aaagtaagta ttttaatata gaactttgat atatataaga atgataatta
    11701 tgctattata agtatacata atatattatt gaaataatat aagtttttag aagtatttta
    11761 agatgagaaa ggagaaaata ctgaaaaata attattctat tataatttgc caaggttttg
    11821 tatatttttc agtttaaata ttatattaca tatgaaaaag aaaaacaatt taaattataa
    11881 ttatgtattt gtagtctatg atgtaggaga aaaaagagta agtaaagttt ttaaagtgtg
    11941 taaaaaatat ctctcgcatt ttcaaaaatc agtttttaga ggtgaaataa ctccatctaa
    12001 gattatgagc ttaaaacgtg atttagaaaa tattatagat aaagataatg attttgtatg
    12061 tataataaag ttgatgaatt ctaatacatt tgaagaagaa atattaggga ataatagtaa
    12121 ttgtgaaaat atgatattat aaatctaatt actatatttg taaaaaataa tagcttatta
    12181 aagagtagta aaattgggat ataatttatg atagagactg caagtagatt tttgtgaaaa
    12241 ggatttactt gcagtatttt tgttatgtat aactgttaac attagtgtac aaaacattat
    12301 caatagcatt tttctataat gaagaaatac tattataatg ggaaaatttt attaatac
//
LOCUS       DAYAOO010000107        12224 bp    DNA     linear   BCT 12-OCT-2024
DEFINITION  TPA_asm: Clostridioides difficile isolate ST8-SSI-h139-18
            SAMN40601845-rid21577343.denovo.108, whole genome shotgun sequence.
ACCESSION   DAYAOO010000107 DAYAOO010000000
VERSION     DAYAOO010000107.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN40601845
            Sequence Read Archive: SRR28438827
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 12224)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12224)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-MAY-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-MAY-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002157583.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002157583.1
            Genome Coverage       :: 163x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/11/2024 16:19:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 4,038
            CDSs (total)                      :: 3,963
            Genes (coding)                    :: 3,930
            CDSs (with protein)               :: 3,930
            Genes (RNA)                       :: 75
            rRNAs                             :: 6, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 60
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 33
            CDSs (without protein)            :: 33
            Pseudo Genes (ambiguous residues) :: 0 of 33
            Pseudo Genes (frameshifted)       :: 7 of 33
            Pseudo Genes (incomplete)         :: 25 of 33
            Pseudo Genes (internal stop)      :: 11 of 33
            Pseudo Genes (multiple problems)  :: 8 of 33
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12224
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN40601845-rid21577343.denovo.108"
                     /isolate="ST8-SSI-h139-18"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Denmark"
                     /collection_date="2018"
                     /collected_by="Statens Serum Institute"
     gene            330..1721
                     /locus_tag="ACGI5H_003381"
     CDS             330..1721
                     /locus_tag="ACGI5H_003381"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430410.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide MFS transporter"
                     /protein_id="HFG9699070.1"
                     /translation="MSSTESVSKKSGHPKSFWLICMTILWERFSYYGLTALLVLFFTA
                     SVAQGGLGLSTQEATSMFGLFTGLIYLTPLVGGWLADKVLGQQKCISIGALLIAIGDF
                     VLFASSTSIAMVWVGLSIIILGNGFFKSSCSNIVGDIYPKTDVSRKDAAYSLFYMAVN
                     VGAFIAPIICGLLSDNVFAVRGASGDIVSYGYKMAFLICGIGMMLGMIIFTLLAPKLL
                     NEVGKYPVTKGNKGEKIEYGPLTKLEKNRIIAMVILFLFVVLFWTAYYQTQSSFMIYV
                     RDNVNRTLFGFEMPVAWLTSLNAILCVALCPVLATLWVKLSHTKRGDFSIPVKMGLGM
                     IIMGVGFIVMVFATLANGPDGMVKASILFIVLTYIFTTVGELFLSPIGLAMFNKLAPA
                     KYATLSMGAWYLTSFFASLLSGKIAGFTATLGFLQIFGGIATVLIIFGLILLGIRNVL
                     TRLMAMDLLTKEK"
     gene            1974..3767
                     /locus_tag="ACGI5H_003382"
     CDS             1974..3767
                     /locus_tag="ACGI5H_003382"
                     /EC_number="3.4.11.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003440248.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0004177 - aminopeptidase activity
                     [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_function: GO:0070006 - metalloaminopeptidase activity
                     [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase P family protein"
                     /protein_id="HFG9699071.1"
                     /translation="MNIKDRLSGLRKFMEEKNIDAYMIPSSDNHQSEYVGDYFKSREF
                     ISGFNGSAGTVIVTKDEAGLWTDGRYFIQAESQLEGSTIKLFKMGQEGCPTTDEYLYK
                     NIPEGGTLGFDGRVISAREGATLAEKLSKKGIKIEYQYDLIDSIWPDRPALSDSKAFL
                     LDVKYCGESFSSKLARLREKMSEKGTSTHVITTLDDIAWLFNIRGGDVKYNPVVLSYA
                     VITLKEVYLFVDESKLNEEILNELAKENVQIKPYNDVYEFVKNIDKTEKVLLDGTKLS
                     YTIYNNIPCEVEKVDEFNPVMFFKAQKNEVELENIRNSHVKDGVAFTKFMYWLKKNVG
                     KMEITEISATQKLEDLRREQEGFFEPSFNTIAAYKEHAAMMHYSATPESNYKLEAEGL
                     FLVDSGGQYYDGTTDITRTTVLGPISDELKLHFTSVARGMINLSKAKFLHGCRGYNLD
                     ILSRSCMWNMGIDYQCGTGHGIGFVLNVHEAPNGFRWRVVPERFDSAVLEEGMVTTNE
                     PGIYIEGSHGIRTENEIVVRKAEKNFYGQFMEFEVVTLAPIDLDGIAPELMNKDEKDY
                     LNWYHKLVYDKISPFLTDEEREWLKVYTRAI"
     gene            complement(3848..5230)
                     /locus_tag="ACGI5H_003383"
     CDS             complement(3848..5230)
                     /locus_tag="ACGI5H_003383"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430415.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide MFS transporter"
                     /protein_id="HFG9699072.1"
                     /translation="MSVLKTQEKLKQPRDLYFCCSIFTFVGLAYYGMKLVLLLFLAEQ
                     VSKGGLGLTPAESASMLASFLAWTYFSPVIGGWVSDRFLGPKNCIILGMLMVSIGYFL
                     GYIANSKMDINIMIFLSGLGIGFYKGNLHTMVGNLYTNDDPRKDGAFSITYMATNLGT
                     LFGPLICGLVANEWFAMKSGLSISMYGYRYVFLFSSITVLIGLFFFIFGNRKFYKPLN
                     NDPINGRESIRKSLEYKKMLASRPLTLIEKKRIIVILVLAFFTVFFWIAYNQASMSIA
                     LYTKEHINLTVGNFQIPTSWIDSYNGLLCVILGPISALVWVKLSQTKKGDLSVPKKMS
                     LGFILLAIAFLFMIVAVIQTGTDPNSIHKASVFWVVGFLTFQSIGEICFSPVGYGMVN
                     KLSPEKYISFLMGVWFLGKFAANKLSGYTQAIIDQLGMLQVFIVIPSFLLIFGIILLI
                     MNKKLVELSN"
     gene            5488..5835
                     /locus_tag="ACGI5H_003384"
     CDS             5488..5835
                     /locus_tag="ACGI5H_003384"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423269.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cupin domain-containing protein"
                     /protein_id="HFG9699073.1"
                     /translation="MIRKKSELQVEVKENLNGGIGKVKLENIIQNEELKGKGRLFKRV
                     ALPVGSSIGVHDHTTDFEVYYILKGKGKVFDNGEFVEVNEGDVVYTADGEKHSIENIG
                     EEDLEFVALVLYM"
     gene            5853..6887
                     /locus_tag="ACGI5H_003385"
     CDS             5853..6887
                     /locus_tag="ACGI5H_003385"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003440238.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF6398 domain-containing protein"
                     /protein_id="HFG9699074.1"
                     /translation="MTGKIEEIKDKINRFCNSNLNQEYKDISFKILQNLLDNNKEIIH
                     SSRADIWSSAILNIVLEQNLLYNKKHPLHITKKEFSKQIGVSLNTINNKSSLIKDVCS
                     IDFLNQDTIAISNVEFWVKETNSKSKSVDLDLEKKKILYKRYIKLSQDANSDIESIRY
                     MEEAVNIGKSMITKEDKELGFWKGLSTRAYMIALESLARKLESINNLKESKKVLEYLI
                     EINPSDEQGIRYKLLNVLIRLNDRTSINKLFELYKEEKSATWMYSKALYYFKNKSMFL
                     ANDSIKVARSKNKYVGLYLLDWRNAFGREFVTEEEKAEAVYYYDENIVIWNEVKGSMD
                     WLLKKMLEFS"
     gene            complement(6936..7985)
                     /locus_tag="ACGI5H_003386"
     CDS             complement(6936..7985)
                     /locus_tag="ACGI5H_003386"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003440236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit IIC"
                     /protein_id="HFG9699075.1"
                     /translation="MEINYKKRNFKSFAKRKNIEISVQRYLIDALSYMALGLFSSLLI
                     GTIFNTLGDNFNISLFTEVISPLAKQVTGPAIAVAIAYGLQAPPLVLFSCALVGACGN
                     ELGGPVGAFVATLFAVEVGKLVSKETKIDILVTPAVTILIGVLVAELIGPAVSAFMTS
                     FGNIIMQATTMQPIIMGALVSALVGIALTLPISSAAICMMLSLGGLAGGAATVGCCCQ
                     MVGFAVMSFRENGVGGLVAQGLGTSMLQVPNIIKNWKIWIPPTVASILLGPLSTTIFK
                     MENIPIGSGMGTCGLVGQFGTVTAMQSAGKGGISMWVGILLLNFILPAIVTLLISEFM
                     RKKGLIKPEDLKLDV"
     gene            8260..9795
                     /locus_tag="ACGI5H_003387"
     CDS             8260..9795
                     /locus_tag="ACGI5H_003387"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430424.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9699076.1"
                     /translation="MIFVKNKKYRKIAIIISIPILLVAQYYLFKFGILRPMVKGVEIE
                     IVDGEYVKDIDKYVVKLNETVTLSTGEYIKVPSYAKNPNIWFNVLDNSGTLKIDGNKM
                     TALKVGYSSVGIMKNSRVLKKATIKVVDPEVESLDMEINGDLKHVGDSATIESTIEVD
                     YDKFKKSYKPVYKSSNENILKIKGNKVSAVGVGKATIYAKCGNKEIERTFRIQARVAE
                     INMDDIKIEVDQNEKLKPDIITSPPGLEPPKIYYELVDSKLPVERAISLSSNGNVVGL
                     REGKDRVRITCGDKSKVITVTVVKETITNDYIQNLVGSHKIVNNKVIIKLEWDYMKDV
                     FDYDIYLKDKLSGESFKKIKSITINESDLGKSNKVYATIEVDMKGNQNIDFDIYVIGK
                     KDSDTTKPSNVINITNGNGNSNNDNNIKDMRVENISANVDRDNNVIRVNWSSISHKDC
                     TYSIYVKNNTNGDGEFTLYQSDIQGNEHTISIPEGDLNLDIYVVANYNGNSSQNSDVI
                     NVR"
     gene            complement(9980..10666)
                     /locus_tag="ACGI5H_003388"
     CDS             complement(9980..10666)
                     /locus_tag="ACGI5H_003388"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003440228.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate/glutamate racemase family protein"
                     /protein_id="HFG9699077.1"
                     /translation="MKTIGLIGGMSWESTITYYQVINTVIKERLGGLHSSKCILYSVD
                     FQEIEECQSSGNWEKSAKILADAAIKLQEAGADFIVICTNTMHKVSDKIQESIHIPLL
                     HIADVTATVLREKEIKKVALLGTKYTMEQDFYKNVIINNGIEVLIPNEEDRIIVNDTI
                     FNELCLGIISESSKKAFLSIIDKLGKQGAEAVILGCTEIGLLIKQNDTSIPLFDTTVI
                     HAIEAALSSI"
     gene            10791..12173
                     /locus_tag="ACGI5H_003389"
     CDS             10791..12173
                     /locus_tag="ACGI5H_003389"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729078.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PLP-dependent aminotransferase family protein"
                     /protein_id="HFG9699078.1"
                     /translation="MPINSFENYPMTWKPKLDNRKPPIYKTLAMLLEEDIKRGNLNPG
                     DKLPPQRELADFLDLNLSTITRAFKLCEEKGLICAKVGKGTFISSDVNVSNTLLYQTE
                     SKDIIELGTVHPPYEQNTYIIDFIKNVLKQPEMDRFLQYMSPSGTYMQKKSIAKWIER
                     NNVYTSEENILLSTGGQNAICATLLGLFKAGDRIATDSLSFSGIKSIAKMIGIQLVPI
                     PQENNEISIEYLESYCKNENIKGIYLIPDYHNPTTHTMSDLSRKKIAKIAKQYNIIII
                     EDAINSIFRDGIQTPIFSLASDNTIYIFSTSKFLCAGLRVAFVVAPKRYIENLENALY
                     NMNLMVSPFTAEIVHRLLYSPIIDKIIEEKRDAIIERNEVADKVLSDYNLIGDKNCSF
                     RWLLLPDELDGKSFEISAKNLGVQVYCAERFSVGNSTVPKAVRICVTAPKDVEELEKG
                     LNIIKSLLKS"
BASE COUNT         4680 a         1478 c         2031 g         4035 t
ORIGIN      
        1 gtgataaaga aataacatgc aaaaaggtat taaaaagaaa tatttttaat ttgaattttt
       61 tcaataaaaa tttacaaaaa tgaaaaaata aacaaaaaag aattgaagat ttaagttgtt
      121 atttaaatat atatatatta agattttctg ctgaagatac taaaaaaata atatttttca
      181 taattttaaa aataataata aaaaaatgaa aatacaggct ataatctatt gagtaaacat
      241 agaaaagatg atattataag tatgtgctaa aatggttaaa gcaatattaa tattaaattt
      301 aactataaaa caaaaggggg cgttttttta tgtcaagtac agaaagcgta tctaaaaaaa
      361 gtggtcatcc gaagagtttt tggcttattt gcatgacaat tttgtgggaa agatttagtt
      421 attatggttt aacagcttta ttggtattat tttttacagc aagtgtagct caaggtggtt
      481 taggtctttc tactcaagaa gcaacatcta tgtttggctt atttacaggt cttatatatc
      541 ttacaccatt agtcggtggc tggttagcag ataaagtttt aggtcaacaa aaatgtattt
      601 ctataggtgc acttttaata gcaataggag atttcgtact atttgcttca tctacatcta
      661 ttgcaatggt ttgggtaggt ctatcaataa ttattttagg aaatggtttt tttaaatcaa
      721 gttgctcaaa tatagttggg gatatatatc ctaaaactga tgtgtcaaga aaagatgcag
      781 catacagttt attctatatg gcagtaaatg taggagcatt tatagctcca ataatatgtg
      841 gattgctttc tgataatgta tttgcagtaa gaggagcaag tggagatata gtatcttatg
      901 gatataagat ggcattttta atttgtggta taggcatgat gttaggtatg attatattta
      961 cacttcttgc accaaaatta ttaaatgaag tcggaaaata tcctgtgact aaaggtaata
     1021 aaggtgaaaa aattgagtat ggaccactta ctaagttgga gaaaaatagg ataatagcaa
     1081 tggttatttt atttttattt gtggtcttat tctggacagc atactatcaa acacaaagtt
     1141 cttttatgat ttatgtaagg gataatgtaa atagaactct atttggattt gaaatgccag
     1201 tagcatggct tacatcacta aatgctatat tatgtgtggc tttatgccca gtattagcta
     1261 ccctatgggt taaattatct cataccaaaa gaggtgattt ctctattcca gttaaaatgg
     1321 gattaggaat gataataatg ggtgttgggt ttatagttat ggtatttgct acattagcta
     1381 atggtccaga tggaatggta aaggctagta tattgtttat agtattgact tatatattta
     1441 caacagtagg tgaattattc ttatctccta taggacttgc aatgttcaat aaattagctc
     1501 cagctaagta tgctacgttg tctatgggag cctggtatct aacaagtttt tttgcaagtt
     1561 tattatcagg aaagattgct ggttttacag ccacacttgg ttttttacag atatttggag
     1621 gaatagcaac agttttaata atatttggtt taatattatt gggaataaga aatgtattaa
     1681 caagattaat ggctatggat ttactaacaa aagaaaaata attcatgacg aattattgta
     1741 aataaatgaa ttactttaaa taaaggaagt tacatttaaa tataaaatta aatgtaattt
     1801 cctctttgat tatgaaaaaa agctttacac aaatagatat tataattaaa attataattg
     1861 tgataattag agtgtataag atttatataa attatacaaa aaatatttat gtaataaact
     1921 ttacatactt atatatttag ttattcaaac tattatttcg aggaggtctt gttgtgaata
     1981 taaaagatag attaagtgga ttaagaaaat ttatggaaga aaaaaatata gatgcctata
     2041 tgattccatc ttctgataat caccaaagtg aatatgtagg agattacttc aaatcaagag
     2101 aatttatatc agggtttaat ggttcagcag ggacggttat tgtgactaaa gacgaagctg
     2161 ggttatggac agatggaaga tattttatac aggcagaatc tcaattagaa ggaagtacaa
     2221 taaaattatt caaaatggga caagaaggtt gcccaactac agatgaatat ttatataaaa
     2281 atattcctga aggaggaact ttaggatttg atggtagagt tatatctgct agagaaggag
     2341 ctacattagc tgaaaaatta tctaaaaaag gtataaagat agaatatcag tatgatttaa
     2401 tagatagtat atggccagat agacctgctt tatcagatag taaagcattt ttattagatg
     2461 ttaaatattg tggagaaagt tttagctcaa aattagctag attaagagaa aaaatgagtg
     2521 aaaaaggtac ttctactcat gtaataacta ctcttgatga tatagcatgg ttattcaata
     2581 taagaggtgg agatgttaaa tataatccag ttgtactttc ttatgcagta ataactttaa
     2641 aagaagttta tctatttgtt gatgaaagta agttaaatga agaaatacta aatgaactag
     2701 ctaaggaaaa tgttcaaata aagccatata atgatgtgta tgaatttgta aaaaatatag
     2761 acaaaactga aaaagtttta ttagatggaa ctaagcttag ttatacaatt tacaataata
     2821 taccttgtga agttgagaaa gttgatgagt tcaatccagt aatgtttttt aaagctcaaa
     2881 aaaatgaggt agaattagaa aatataagaa attcacatgt aaaagatggt gtagctttca
     2941 ctaaatttat gtactggtta aagaaaaatg taggtaagat ggaaatcact gaaataagtg
     3001 ctactcaaaa attagaggac ttaagaagag agcaagaagg tttctttgag ccaagtttca
     3061 atacaattgc tgcatataaa gagcatgctg caatgatgca ctatagtgca actccagagt
     3121 caaattataa attagaggca gaaggattat ttttagtaga ttcaggtgga caatattatg
     3181 atggaactac tgatataact aggactacag ttttaggacc tataagtgat gaattaaaac
     3241 tacactttac ttctgtagca agaggaatga taaatctttc taaggctaag ttcttgcatg
     3301 gttgtagagg atataactta gacatactat ctagaagttg catgtggaat atgggaattg
     3361 attatcaatg tggaactgga catggtatag gatttgtgct aaatgttcac gaagctccaa
     3421 atggatttag atggagagta gtacctgaaa gatttgatag tgcagttctt gaagaaggaa
     3481 tggtaactac taatgaacca ggtatatata tagaaggttc tcatggtata agaacagaga
     3541 atgaaattgt agttagaaaa gctgaaaaga atttctatgg tcaatttatg gaatttgaag
     3601 ttgttacgtt agctcctatt gacttagatg gtatagcacc agaattaatg aataaggatg
     3661 aaaaagatta tttaaattgg tatcataagt tagtttatga taaaatatca cctttcttaa
     3721 ctgatgaaga aagagaatgg ttaaaagttt acactagagc tatatagttt gtactagata
     3781 caataaaaat cgaggtatta taatgcctcg attttttatt gtatatttta ttaactttaa
     3841 aaaattttta atttgataat tctactaatt ttttattcat tataagtagt ataattccaa
     3901 atatcaataa aaatgatggt atcactatga agacttgtaa cataccaagt tggtctataa
     3961 tagcttgcgt atagccagat aatttatttg ctgcaaattt gcctaaaaac caaacaccca
     4021 ttaggaatga aatatacttt tcaggcgaaa gtttatttac cataccatac ccgactggag
     4081 aaaagcaaat ttctcctata ctttggaatg ttaaaaatcc aactacccaa aatacacttg
     4141 ctttgtgaat tgaattaggg tctgttcctg tttgtataac tgctactatc ataaacaaaa
     4201 atgctatggc taatagtata aaacctaagc tcattttttt tggcacactt aaatcgcctt
     4261 ttttagtttg agataatttt acccatacta aagcagagat aggtccaaga ataacacaaa
     4321 ggagaccatt gtatgaatct atccatgaag taggaatttg aaaattgcca acagtaagat
     4381 ttatgtgttc ctttgtatag agtgcaatag acatagaggc ttggttatat gctatccaaa
     4441 aaaatactgt gaaaaaagct aacaccaata ttactattat tctttttttc tcaatcaaag
     4501 ttaaaggtct tgaagcgagc attttcttat attctagtga ttttcttata gactctctcc
     4561 cgttaatagg gtcattattc aaaggtttat aaaactttct gtttccaaat ataaagaaga
     4621 ataaacctat tagaaccgta attgatgaaa ataaaaatac atatctatat ccatacatac
     4681 ttatagataa tccgcttttc atagcaaacc attcattagc aactaaaccg catattaaag
     4741 ggccaaataa agtacctaga ttagtagcca tatacgtaat agagaaagct ccatcttttc
     4801 ttgggtcatc attggtatat aagtttccaa ccatagtatg taagtttcct ttataaaaac
     4861 ctattcctaa tccagataaa aatatcatga tgtttatatc catcttacta tttgctatgt
     4921 atcctagaaa ataaccaatt gaaaccatta gcattccaag tataatacag tttttgggac
     4981 ctaaaaatct atcactgacc catccaccaa taactggaga gaaataagtc catgctaaaa
     5041 aagatgcaag cattgatgcg gattctgctg gtgttaaccc taaaccacct ttggagactt
     5101 gttcagctaa aaacaataat aataccaatt tcataccata gtatgcaagt cctacaaagg
     5161 taaatattga acagcagaaa tataaatctc taggttgttt aagtttttct tgcgttttta
     5221 aaactgacat atgtcgagaa cctccagata aatagtttaa caaaatttta ccatactata
     5281 tgagtatatg tttttttcat atagacgtca acttgtaaga taatttaatt aagtcgaaat
     5341 atatgtaaaa atagtatcat ttttgtgtat tcagtaatat ttttttatga taatatatgt
     5401 tattattata ttaaaataca aacatattta tggaaaggat atgccaattt agtagttaga
     5461 ttgattgttt ggcaggtggg atgagctatg ataagaaaga aatctgaatt acaagtagaa
     5521 gtaaaagaaa atttaaatgg tggtatagga aaggttaagc ttgaaaacat aatacaaaat
     5581 gaagagctta aaggaaaagg aagactattt aaaagagtag ctttaccagt aggaagttca
     5641 attggtgtgc atgaccatac aacagatttt gaagtatatt atatactaaa gggaaaaggt
     5701 aaagtatttg ataatgggga atttgtagaa gtaaatgagg gtgatgtagt gtatacagct
     5761 gatggcgaaa aacattctat agaaaatata ggagaagaag atcttgagtt tgtagcacta
     5821 gttttatata tgtaaaatat ggaggaggag tcatgacagg caagatagaa gaaattaagg
     5881 acaagataaa tagattttgc aactccaatt taaatcaaga atacaaagat ataagcttta
     5941 aaattttgca aaacctttta gataataata aagagataat tcattcttct agagctgata
     6001 tatggtcttc agctatacta aatatagttt tagaacaaaa tcttttatac aataagaagc
     6061 atccactaca tataacaaaa aaagagtttt caaaacaaat aggtgtttct ttaaatacta
     6121 taaataataa atcgtcttta ataaaagatg tttgtagtat tgacttttta aatcaagata
     6181 ctatagctat ttctaatgta gaattttggg taaaagagac taattccaaa tcaaagtctg
     6241 tagatttaga tttagaaaag aagaaaatac tatataaaag atatattaag ctatcacaag
     6301 atgcgaatag tgatattgaa tcaattagat atatggagga agctgtaaat ataggtaaaa
     6361 gtatgattac taaagaagat aaagaacttg gattttggaa aggtttatct accagagcct
     6421 atatgatagc acttgaatcc cttgctagaa agttagaaag tattaataat ctaaaggagt
     6481 ccaaaaaagt attagaatat ttaatagaaa ttaatcctag tgatgagcag ggaataagat
     6541 acaaattatt aaatgtatta attagattaa atgatagaac ttcaataaat aaattatttg
     6601 aactttataa agaagaaaaa tctgctacat ggatgtacag taaagctctt tattacttta
     6661 aaaataaaag tatgtttttg gcaaatgatt ctattaaggt tgctagaagt aaaaataagt
     6721 acgttggatt atatttgtta gattggcgaa atgcttttgg tagagaattt gttacagagg
     6781 aagaaaaggc agaagctgtc tattactatg atgaaaacat agtgatttgg aatgaagtta
     6841 aaggttctat ggattggcta ttaaaaaaaa tgttggaatt ttcataaaaa aaactactcc
     6901 ttacttttat ataagtcaaa ggagtagttt ttaatttata catctagttt taaatcttca
     6961 ggttttatta gacctttttt tctcataaat tctgaaatca acaaagttac aatagcagga
     7021 agtataaaat taagtaaaag tataccaacc cacatagata tacctccttt tccagcactt
     7081 tgcatagcag ttactgttcc aaattgtcca accaatccac aagtacccat accagaacca
     7141 ataggaatat tctccatttt gaatattgtt gtagataatg gtccaagtaa tattgaagct
     7201 acagtaggtg gtatccaaat tttccaattt tttattatat taggtacttg caacatagat
     7261 gtcccaagac cttgtgccac aaggccacca actccatttt ctctaaagct cataacagca
     7321 aagcctacca tttggcaaca acaacctaca gttgctgcac caccagcaag accacctaaa
     7381 cttaacatca tacaaatagc tgcactactt ataggtaatg taagagctat tccaacaagt
     7441 gcagagacta aagctcccat tattataggt tgcatagttg tagcttgcat tattatattt
     7501 ccaaatgaag tcataaaagc agaaacagct ggaccaataa gttcagctac aagtactcca
     7561 attagtattg ttacagcagg tgtaaccaat atatctattt ttgtttcttt tgaaactaat
     7621 tttccaacct ctacagcaaa aagtgtagcg acaaatgctc caacaggtcc tcctaattca
     7681 ttaccacaag ctccaacaag tgcacaagaa aatagtacaa gtggaggtgc ttgaagtcca
     7741 tacgcaatag ccactgctat agctggacca gtaacctgtt tagcaagagg gcttataact
     7801 tcagtaaaaa gagaaatatt gaaattatct cctaatgtat tgaaaattgt tccaattaaa
     7861 agggacgaaa aaagaccgag tgccatataa cttagtgcgt caataagata cctttgaaca
     7921 gaaatttcaa tattttttct tttagcaaat gatttgaaat ttcttttttt ataattgatt
     7981 tccaatttaa aatcctcctc atataatata agtataattt ctttttaatt aattatataa
     8041 cttttcagct gacaagacaa atgttatttc actaaaatta gactattgta atagtaagaa
     8101 attaacatta attttagttt taaattttaa atttatggtt tataattagt atagggatat
     8161 tctgaaatat aataattttc cagtttatcc caatatttaa cttaggtaga ttgcttacaa
     8221 aacaaatgat tatatattag gctaaaagga agtggataga tgatatttgt aaaaaataag
     8281 aaatacagaa aaattgccat aattatatct attcctatat tgcttgttgc gcagtactac
     8341 ctttttaaat ttggaatact tagaccaatg gtaaagggag tagaaattga aattgtagat
     8401 ggggaatatg ttaaagatat agataaatat gtagtaaaat taaatgaaac agttactttg
     8461 tctacaggtg aatatattaa ggttccttcg tatgctaaaa atccaaatat ttggtttaat
     8521 gtattggata actcagggac tttaaaaata gatggaaata aaatgacagc attaaaggtt
     8581 gggtattctt ctgtgggtat catgaaaaat tcaagagtat taaaaaaggc tactataaaa
     8641 gtagtagacc cagaggtaga atcactagat atggagatta atggggattt aaaacatgtt
     8701 ggtgatagtg ctactataga aagtacaata gaagttgatt atgataagtt taaaaaatca
     8761 tataagccag tttataagag tagcaatgaa aatattttaa aaatcaaagg aaataaagta
     8821 agtgcagttg gagttggtaa agctacaata tatgctaagt gtggaaataa agaaattgag
     8881 agaacattta ggattcaagc tagagttgct gaaataaata tggatgatat aaaaatagaa
     8941 gttgaccaga atgaaaaatt gaaaccagat ataataactt ctccgcctgg tttagaacca
     9001 ccaaaaatat attatgagtt agtagattca aaattacctg tagaaagagc aataagttta
     9061 agtagtaatg gaaatgttgt agggcttaga gaaggtaaag atagggtgag aataacttgt
     9121 ggagataaat ctaaagtaat aacagtaaca gtagtcaaag aaactataac gaatgactat
     9181 atacaaaact tggttggttc acataaaata gtaaacaata aagttattat taaacttgaa
     9241 tgggattata tgaaagatgt ctttgattat gatatatatc ttaaagataa gttgtcagga
     9301 gaatcattta agaaaattaa atctataact ataaatgaaa gtgatttagg taagtctaac
     9361 aaggtatatg caactataga agtagatatg aagggtaatc aaaatataga ttttgatatt
     9421 tatgtcatag ggaaaaagga ttcagataca actaagccaa gtaatgtaat aaatattacc
     9481 aatggaaatg gaaattcaaa taatgataat aatattaaag atatgagggt agaaaatata
     9541 tcagctaatg ttgatagaga taataatgtc attagagtta actggagtag tatatctcat
     9601 aaggactgta cttacagtat atatgtaaaa aataatacta atggagatgg agaatttact
     9661 ctatatcaaa gtgatataca gggaaatgag catactataa gtattcctga aggagattta
     9721 aatctagata tttatgttgt tgcaaattat aatggaaata gctctcaaaa tagtgatgtt
     9781 ataaatgtaa gatagatttg tatacaaatt gaaagtgttg agtttattta aatattaaat
     9841 taagaaaaag gatagtatag ggtaattata ctatcctttt ttgttacaat atataggttt
     9901 aaaatctcta gtaatataaa ttataaaaag tcttatttac acaaatctat agatattttt
     9961 tttattaatc aatattgtct taaattgaac ttagtgcggc ttctattgca tgtattactg
    10021 tcgtatcaaa tagtggaata gaagtgtcat tttgtttaat taaaagacct atttctgtac
    10081 atcctaatat aacagcctct gcaccttgtt tgccaagctt atctataata gataagaaag
    10141 ctttttttga agattcagat ataattccta agcaaagttc attaaatatt gtgtcattta
    10201 ctattatacg gtcttcttca tttggaatta agacttcaat tccattatta ataattacat
    10261 ttttataaaa atcttgttcc attgtatatt tagtacctaa taaggccact ttttttattt
    10321 ctttttccct taataccgta gcagttacat ctgctatgtg aagtaatgga atatgtatac
    10381 tttcttgtat tttatctgat accttatgca tagtattagt acagataaca ataaaatctg
    10441 cccctgcctc ttgtaattta attgcagcat cagctaaaat tttggcgctt ttttcccaat
    10501 ttccactaga ttggcattct tcaatttctt gaaaatctac actgtaaagt atacatttag
    10561 aagagtgtag tccacctaat ctttctttta ttactgtatt aataacttga taatatgtaa
    10621 tggtactttc ccaactcata ccaccaatta agcctatagt cttcatatta tacctctctt
    10681 atttatttat tttgaaatag ctatttacaa atacaagtat agcatctaaa atagaagcat
    10741 acaatgataa aattgtatgg agtacaatta taattaagag gagtaattat atgccaataa
    10801 attcttttga aaactatcct atgacatgga aaccaaaatt agataaccga aaaccaccaa
    10861 tatataaaac tttagcaatg ttattagaag aagatattaa aagaggaaat ttaaatcctg
    10921 gagataaact gcctccacaa cgggaattag cagattttct agatttaaac ttaagtacaa
    10981 taacacgagc atttaaactt tgcgaagaaa agggactaat atgtgcaaaa gtgggaaagg
    11041 gaacattcat ttcttctgat gtaaatgtaa gtaatacatt attatatcaa acggaatcaa
    11101 aagacataat tgaattaggg acagttcatc ctccgtatga gcaaaataca tatattattg
    11161 actttattaa aaatgtacta aaacaaccag aaatggatag gtttttacaa tacatgtctc
    11221 catctggcac atatatgcaa aaaaagtcaa ttgcaaaatg gatagaaaga aataatgtat
    11281 acaccagtga agaaaatata ttattatcta caggagggca aaatgctata tgtgcaactt
    11341 tactaggatt atttaaagct ggtgatagaa ttgctacaga ttctttaagt ttttctggaa
    11401 ttaagtcaat agctaaaatg ataggtattc aattagtccc aattcctcaa gaaaataatg
    11461 aaatatcgat tgaatatctt gaaagttatt gtaaaaatga aaatataaaa ggcatatatc
    11521 ttataccaga ttatcataat ccaacgacac atactatgtc tgatttatct cgtaaaaaga
    11581 tagccaagat agcaaagcaa tataatataa taattattga agatgctata aatagcattt
    11641 ttagagatgg tatacaaact cccatatttt ctttagctag tgataatact atatatattt
    11701 ttagtacatc taaattttta tgtgctggtc ttagagtagc atttgtagtt gctccaaaac
    11761 gatatataga aaatttagaa aatgcactat ataatatgaa tctaatggtt tctccattta
    11821 cagcagaaat agtacaccgt ttattatatt ctcctattat agataaaatt atagaagaga
    11881 aaagagatgc aattatagaa agaaatgaag ttgctgataa agttttgtca gattataatt
    11941 tgattggtga taagaattgc agttttcgtt ggttacttct tcctgatgaa ttggatggaa
    12001 aatcatttga aatttctgca aaaaatctag gagttcaagt atattgtgct gaacgatttt
    12061 cagtaggaaa ctctacagtt ccaaaagcag ttcgtatttg tgtaacagct ccaaaagatg
    12121 tagaagaatt agaaaaaggg cttaatataa taaagtcact tcttaagagt taaatttatt
    12181 ttactattat ttaattaaat aaataaaaag gcggagaaat ttat
//
LOCUS       DAYAOO010000108        12040 bp    DNA     linear   BCT 12-OCT-2024
DEFINITION  TPA_asm: Clostridioides difficile isolate ST8-SSI-h139-18
            SAMN40601845-rid21577343.denovo.109, whole genome shotgun sequence.
ACCESSION   DAYAOO010000108 DAYAOO010000000
VERSION     DAYAOO010000108.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN40601845
            Sequence Read Archive: SRR28438827
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 12040)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12040)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-MAY-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-MAY-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002157583.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002157583.1
            Genome Coverage       :: 163x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/11/2024 16:19:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 4,038
            CDSs (total)                      :: 3,963
            Genes (coding)                    :: 3,930
            CDSs (with protein)               :: 3,930
            Genes (RNA)                       :: 75
            rRNAs                             :: 6, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 60
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 33
            CDSs (without protein)            :: 33
            Pseudo Genes (ambiguous residues) :: 0 of 33
            Pseudo Genes (frameshifted)       :: 7 of 33
            Pseudo Genes (incomplete)         :: 25 of 33
            Pseudo Genes (internal stop)      :: 11 of 33
            Pseudo Genes (multiple problems)  :: 8 of 33
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12040
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN40601845-rid21577343.denovo.109"
                     /isolate="ST8-SSI-h139-18"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Denmark"
                     /collection_date="2018"
                     /collected_by="Statens Serum Institute"
     gene            153..485
                     /gene="saoD"
                     /locus_tag="ACGI5H_003390"
     CDS             153..485
                     /gene="saoD"
                     /locus_tag="ACGI5H_003390"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430785.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0018942 - organometal metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DsrE-related protein SaoD"
                     /protein_id="HFG9699079.1"
                     /translation="MKVAYIFSSTNTHKILDKMIIPQLEQGTHGVDVLGMFFFMDNTL
                     FLSKGNPVGERLSKLHEKTDMIIMACDQCAIERGIENNLVDGATIGCFPNLYACLGSA
                     GVDQVITL"
     gene            575..832
                     /gene="saoT"
                     /locus_tag="ACGI5H_003391"
     CDS             575..832
                     /gene="saoT"
                     /locus_tag="ACGI5H_003391"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_240067706.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0018942 - organometal metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_except=(pos:608..610,aa:Sec)
                     /transl_table=11
                     /product="thioredoxin-like (seleno)protein SaoT"
                     /protein_id="HFG9699080.1"
                     /translation="MSKILVEFINTUPSCDEHGVFIKKMSEKYADKLEIKLYQAGKDF
                     SYIKKYGIITKGTLIINQKKKYDRLNKDTIERAIVEAINNN"
     gene            859..1944
                     /gene="saoE"
                     /locus_tag="ACGI5H_003392"
     CDS             859..1944
                     /gene="saoE"
                     /locus_tag="ACGI5H_003392"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416824.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0015562 - efflux transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0018942 - organometal metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="efflux transporter SaoE"
                     /protein_id="HFG9699081.1"
                     /translation="MNILEIVLNGVKDTIVASIVTLNGASGWLMISFILAGVLHNVLT
                     PRRFQKQLGNKKFSSLIKSTISGMFLPICSCGVIPLGISMYYSGAYLGPVLAFMTSTP
                     IINPIAVVLCLGLLGPKVTIIYLIAGFLVPFLVGFLGNCFGKEELSLHNDSEEEVIEL
                     EEEKRSFMGNMIDGLKWSFGELALTISKYVVMGMVFAGFITTIFPNSIIQKYLGNPGL
                     LSLGSIAILACVMYVCAVGHIPFIAALVASGASPGIAITFLIAGAATNLPELISMFKL
                     IGKRTVIIYSVTLTLSSIIIGYITNLLLVNNNSVNLDATNSSIQLANKLMLNIPDSFE
                     YVCTILIILFAFKSIIPKMKEVIGNHA"
     gene            1937..2395
                     /gene="saoC"
                     /locus_tag="ACGI5H_003393"
     CDS             1937..2395
                     /gene="saoC"
                     /locus_tag="ACGI5H_003393"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0018942 - organometal metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Cys-Cys-COOH (seleno)protein SaoC"
                     /protein_id="HFG9699082.1"
                     /translation="MLKKIVIISCIVVVLIILSKIVDDNIKEDASIPNVNKETLEYFR
                     KNYKEDIITCAEEDLNNDGKKDLVVIYKKSNNSNEMVVVVSDKNSHYITKPIPAPIEN
                     QTITFKNIDDKAPIEVIVSGSKNGNVGYAIYRVEGKKFVDLFGEDMDKCC"
     gene            2430..3521
                     /gene="saoX"
                     /locus_tag="ACGI5H_003394"
     CDS             2430..3521
                     /gene="saoX"
                     /locus_tag="ACGI5H_003394"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454662.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA];
                     GO_process: GO:0018942 - organometal metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding subunit SaoX"
                     /protein_id="HFG9699083.1"
                     /translation="MKLSKKIQALILFGVMGTSILTGCSSKPKEKEEAKTGKDDYTIT
                     VGYYNCDHMTAGPVAESAGIYKDLGLNVKTVGNGKVPEAMAAGKMDAGYIGTKGLVGA
                     IPKGSPITIAANNHTGGSEYLIVSKDIKEPKDLIGKKIATDMSDFLWTSDYGPETGLP
                     TDPSKYEVVNMDSDKDKYLALKTGKIQAFTSCDPWGSVAENDGAGKIIASTQYKEKAN
                     GKEYNCCSFSLNKNFIKEHPDLAKKLVLAHTKAIEYIYTNPAEAAKIFAKYYNVEEEV
                     ALRTIYKKTVGEGRTLTWKVTGEEYKNNLQMYKDLKALDDIPKYEDTIDTSLLDSCGA
                     DDFDKFIKEKVNPEFPEGMSYEDWKAKVL"
     gene            3535..4323
                     /gene="saoB"
                     /locus_tag="ACGI5H_003395"
     CDS             3535..4323
                     /gene="saoB"
                     /locus_tag="ACGI5H_003395"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_239591066.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA];
                     GO_process: GO:0018942 - organometal metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_except=(pos:3748..3750,aa:Sec)
                     /transl_table=11
                     /product="ABC transporter substrate-binding
                     (seleno)protein SaoB"
                     /protein_id="HFG9699084.1"
                     /translation="MKNIIILFIIILGSIFIIFFNFEDKEEIKGKLRIGVSDDTSGFV
                     INYMVNRDYFENIKVSDIMDIFTINDCUASTMQWALSSEEIDIAIICKDAAKQYVNVN
                     SGFEIVGTVVQNSDIFLLSDNNPEKIGVIQNRDYQSELVKKYYKNVEVAPLLGTALAY
                     GLESNLVDGVVIDCIKSIGLEGKRKSTTKLGDYDTYVLVVNKEFKKSKAYSDFITLYN
                     KSVDALKNKATFKKVLKEYRNIRNIDMEEISNWKLKFLKIKAID"
     gene            4347..5090
                     /gene="saoP"
                     /locus_tag="ACGI5H_003396"
     CDS             4347..5090
                     /gene="saoP"
                     /locus_tag="ACGI5H_003396"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_239591060.1"
                     /note="Most members of this family are selenoproteins with
                     the selenocysteine residue at the channel-gating position;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology.
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA];
                     GO_process: GO:0018942 - organometal metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_except=(pos:4911..4913,aa:Sec)
                     /transl_table=11
                     /product="ABC transporter permease subunit SaoP"
                     /protein_id="HFG9699085.1"
                     /translation="MDILYKIILLVIIFLVWHFAAKDIGSSLLLPMPVDVIKGFFFCV
                     TDAETVTNLFITLQRVLKGFMYALLFGLPIGFIMGFSKTFERVLSPVVDSVRQVPIMA
                     WVPLTIVWFGIGDGPTIFLIAFSGVFPIILNTIQGVRAISKDYYNAARSMGASPIVIF
                     TNVIVPASLPDILTGSRIAISTGWMSVIUAEFIATSAGLGYSMVQAQTLMHTDVLIGL
                     MIFAALIGFIIDRVLKFINKILCRWRFAD"
     gene            5090..5842
                     /gene="saoA"
                     /locus_tag="ACGI5H_003397"
     CDS             5090..5842
                     /gene="saoA"
                     /locus_tag="ACGI5H_003397"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430772.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA];
                     GO_process: GO:0018942 - organometal metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein SaoA"
                     /protein_id="HFG9699086.1"
                     /translation="MKLSVRDINKTFVNNRVHTKVLEDISMDIDDGQFVCLLGPSGCG
                     KTTLLTIIGGFQKSERGDVFINDKRVKKPGIDRAFIFQNYALFPWKTIRGNVLFPMKQ
                     QKIPKEKREEMLEELLVMSDLKGKEKLFPHQLSGGMKQRVAMIRALACNPEVLLMDEP
                     LGAVDFQMRQNLQEELERIWIKKKITALMVTHDVDEAVYMSDRVIVMSRDKGRIIDDI
                     NIDIPRPRIRGSQKYEEYKNKLTDTLSKCYEV"
     gene            5855..6496
                     /gene="saoL"
                     /locus_tag="ACGI5H_003398"
     CDS             5855..6496
                     /gene="saoL"
                     /locus_tag="ACGI5H_003398"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_238476746.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0018942 - organometal metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_except=(pos:6338..6340,aa:Sec)
                     /transl_table=11
                     /product="MerB-like organometallic lyase SaoL"
                     /protein_id="HFG9699087.1"
                     /translation="MSQIEKYNSLDNTQQKIRISIMDMIIDKGSSVTLQEVTEYVSKK
                     LNIEKEYIERTLQYFIYKNIMVVDGNSINFIYPVSALPTNHKVTLRDNRSFSAMCAID
                     AIGTSCTFNQDIKINSICSATGKEIEVIIKNEKIEYVNNPNLRVLHINLDKHLNWAAS
                     CUNIMNFFWTKSDFDAWTNEAGLSDDEDIYCLDINEAIVESYKIFKLKQKVLS"
     gene            complement(6632..7453)
                     /gene="yidA"
                     /locus_tag="ACGI5H_003399"
     CDS             complement(6632..7453)
                     /gene="yidA"
                     /locus_tag="ACGI5H_003399"
                     /EC_number="3.1.3.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897541.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sugar-phosphatase"
                     /protein_id="HFG9699088.1"
                     /translation="MYKLIALDIDGTILNTQKRITPEVFESIQEAKRAGAKVVITTGR
                     PLPGVKELLNQLNLTDEGDYVICFNGAIIQEVKSEKIIHDVEMSLDDFDFIYNNVCKK
                     YKTKIHINTMTNLITPNETPGKYTLHEAKLNNIEVKYIQKDKIDESIKICKIMIVDEP
                     ERLEEIIQQLPKNLFNKYTIVRSAPFYLEFLGKTTNKGTALKTLCTNLNIPIENAIAV
                     GDEENDQHMIKYAGLGVAMGNARNSIKEIADYVTDTNNENGVAKVINKYILNKAI"
     gene            7946..9640
                     /locus_tag="ACGI5H_003400"
     CDS             7946..9640
                     /locus_tag="ACGI5H_003400"
                     /EC_number="3.4.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454655.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004222 - metalloendopeptidase activity
                     [Evidence IEA];
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="M3 family oligoendopeptidase"
                     /protein_id="HFG9699089.1"
                     /translation="MKFSEFKYERPNYNSMKKEFLSCVEDINNSRNYKEQQKNIHKIN
                     LLRNKIETLSNIASIRYSTDTFNKFYKEEKNYWDEYMPLYEELNSYFYNAIVNSKFKY
                     DLIKEFGEQFFTIVEYSLKSFSKEIISELQEENKLCSEYTRLLASAEIMFDGKIRNLS
                     GMGKFMYSKNRKTRELANKAYYNFFEENETKFDDIFDKLVKLRDKMSKKLGFEDFVEL
                     GYIRMMRSDYREYMIKNVRKQVLKYVVPMANELYEKQAKRIGLEYLSYIDEGVEFLTG
                     NASLKGDSRYIIKNGKRMYSELSKETNEFFDFMLENELMDLETKKGKGAGGYCTYIPD
                     YKSPFIFSNFNQTADDIDVLTHEAGHAFQLYMSRWIDMPEINFPTLDSCEIHSMSMEF
                     ITWPWMDLFFKEDTDKYKFTHLSSSIKFIPYGVIVDEFQHYIYKNPNVDKSKRKEIWR
                     FLEKKYLPHRKYGDNSFLERGCWWFKQGHIFKNPFYYIDYVLAQICALQFWKKMIQDR
                     DAGWKDYINICKVGGTKSFLDIVSMGNLYSPFDDGCIESIIGDVKSWFDEINDSKL"
     regulatory      9972..10082
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00504"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="glycine riboswitch; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="glycine"
                     /db_xref="RFAM:RF00504"
     gene            10186..10557
                     /locus_tag="ACGI5H_003401"
     CDS             10186..10557
                     /locus_tag="ACGI5H_003401"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903157.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GrdX family protein"
                     /protein_id="HFG9699090.1"
                     /translation="MIIITNNPKVKEEVQGREVLFKDTTYIGILEASRDLIHEGYELL
                     SHPLYGSVKPNETPYRTVILKKGNRLDINSLTLIEEAIITASKFQNNKKTPKWTESVQ
                     DDFRVIDYDIFYNTIQRMQYE"
     gene            10652..11599
                     /gene="trxB"
                     /locus_tag="ACGI5H_003402"
     CDS             10652..11599
                     /gene="trxB"
                     /locus_tag="ACGI5H_003402"
                     /EC_number="1.8.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416869.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0004791 - thioredoxin-disulfide reductase
                     (NADPH) activity [Evidence IEA];
                     GO_function: GO:0071949 - FAD binding [Evidence IEA];
                     GO_process: GO:0019430 - removal of superoxide radicals
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin-disulfide reductase"
                     /protein_id="HFG9699091.1"
                     /translation="MENVYDLVIIGSGPAGLAAGLYGARAKLKTLILEKDKTGGQIVI
                     THEIANYPGSVPNATGPSLIARMVEQCKEFGAEMLRDNIVDTELDGDIKVLKGEKAEY
                     RAKAVIIGTGATPRKIGCPGEKELTGKGVSYCATCDADFFEDFEVFVVGGGDSALEEA
                     MYLTKFARKVTIVHRRQGFRCAKSVEEKAKANPKIEFLLDTVIEEIKGDGILESVVFK
                     NKVTGETHEYFADEEDGTMGVFVFVGLDAQTDLFKGKVDMDEKGYIITDEDMRTNIPG
                     VFAAGDCRSKTLRQVVTATNDGAIASIVAEKYIDEKFGN"
     gene            11703..12020
                     /locus_tag="ACGI5H_003403"
     CDS             11703..12020
                     /locus_tag="ACGI5H_003403"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416870.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin domain-containing protein"
                     /protein_id="HFG9699092.1"
                     /translation="MLDLDKATFEEEVLNAEGFVFVDFWSEGCEPCKALMPDVHKLAE
                     TYGDKIKFCKMDTTKARRLAIKQKVLGLPTMAIYKDGEKVDEVTKDDATVPNIENMIK
                     KYL"
BASE COUNT         4772 a         1250 c         2146 g         3872 t
ORIGIN      
        1 aatcaatcaa taatttaata aaaatagata aatactatat acacttttaa taatatagtt
       61 aatatctatt ttacagataa ataagaataa acttataata taattgtatc tgtaaaattt
      121 tgtaaaatat aaaaagtata gggggaataa aaatgaaagt agcttatatt tttagtagta
      181 ctaatacaca taaaattcta gacaaaatga taataccaca acttgaacaa ggaactcatg
      241 gagtagacgt tctagggatg tttttcttta tggataatac cttattttta tctaaaggta
      301 atcctgtagg cgagagacta agtaaattac atgaaaaaac tgatatgata ataatggctt
      361 gtgaccaatg tgctatagaa agaggtatag agaataattt ggttgatgga gctacaattg
      421 gatgtttccc aaacctatat gcttgtttag gcagtgcagg tgtggaccaa gttataacgt
      481 tataaattag tataggatac aatccataga aaaatttatt ttctgtggat tattttaagt
      541 aaaagataaa ttgtttaaag taggggatta acaaatgtct aaaattttag ttgaatttat
      601 aaacacttga ccatcttgtg atgaacatgg agtgtttata aaaaaaatgt cagaaaaata
      661 tgctgataaa ttggaaataa aattatatca agcagggaaa gatttttcgt atataaaaaa
      721 atatgggatt ataacaaaag gaactttaat aataaatcag aaaaagaaat atgatagatt
      781 aaataaagat acaattgaaa gggcaatagt agaagctata aacaataatt aaaagtttaa
      841 aaattaggag tatcaaaaat gaatatatta gaaattgttt taaatggagt taaagatact
      901 atagtagctt ctatagttac actgaatgga gcatcaggat ggcttatgat aagttttata
      961 ttggcaggtg tacttcacaa tgttttaact ccaagaaggt ttcaaaaaca acttggaaat
     1021 aagaaatttt cttctttaat taaaagtact atctcaggaa tgtttttacc aatatgtagt
     1081 tgtggagtaa taccacttgg aataagtatg tattattcag gagcatattt aggaccagta
     1141 cttgctttta tgacatcaac tccaataata aatccaatag ctgtagttct ttgtctaggt
     1201 cttttaggtc ctaaagttac aatcatttat ctaatagctg gttttttagt accattttta
     1261 gtaggatttt taggaaattg ttttggaaaa gaagaattat cacttcataa tgattcagag
     1321 gaagaagtaa tagaattaga agaagaaaaa agaagtttta tgggaaatat gattgatggt
     1381 cttaaatggt cttttggtga attagccctt actattagta aatatgtagt aatgggtatg
     1441 gtttttgcag gatttataac aactattttt ccaaatagta taattcaaaa atatttagga
     1501 aatccaggtt tgctatctct tggaagtata gcaatacttg catgtgttat gtatgtatgt
     1561 gctgtaggac atataccgtt tatagcagcc cttgttgcaa gtggagcatc tcctggtata
     1621 gcgataacat ttctaatagc tggagcagct acaaatctac cagaacttat aagtatgttt
     1681 aaacttattg gaaaaagaac tgttattata tattctgtaa ctttgacact gtcttcaata
     1741 ataattggat atataacaaa tttactttta gtgaataata actcagtaaa tttagatgca
     1801 acaaattctt caatacagtt ggcaaataaa ctaatgttaa atatacctga tagttttgag
     1861 tatgtatgta ctattttaat tattttattt gcatttaaat caataatacc aaagatgaaa
     1921 gaggtcatag gaaatcatgc ttaaaaagat agttataata tcctgtatag tagttgtgtt
     1981 aatcatttta tcaaaaatag ttgatgataa catcaaagaa gatgcttcta ttccaaatgt
     2041 gaataaagaa acattagaat attttagaaa aaattataaa gaagacataa taacttgtgc
     2101 tgaagaagac ttaaataatg atggaaaaaa agatttagta gttatatata aaaaaagcaa
     2161 taattcaaat gaaatggtag tcgtagtttc tgataaaaat agccactata taacaaagcc
     2221 aataccagca cctatagaga atcaaacgat aacctttaaa aatattgatg ataaagcacc
     2281 aatagaagta attgtatcag ggtctaaaaa tggtaatgta ggatatgcta tttacagagt
     2341 agagggtaaa aaatttgttg atttatttgg cgaagatatg gacaaatgtt gctaaaaata
     2401 aaaataatac ataaaggtgg gaaatttata tgaaattatc taagaagatt caagcattaa
     2461 tcttatttgg tgtaatgggt acatctatat taacaggatg tagtagtaaa ccaaaagaaa
     2521 aagaagaagc aaaaactgga aaagatgatt atacaataac agtaggttat tataattgtg
     2581 accatatgac tgcgggacca gtagcagaat cggcaggaat atataaagat ttaggtctta
     2641 atgtaaaaac tgttggaaat ggtaaagttc ctgaagctat ggcagcagga aaaatggatg
     2701 caggttacat aggaactaag gggttagttg gagcaatacc taagggttcg ccaataacaa
     2761 tagcagctaa caaccatact ggtggttctg aatatttaat agtttcaaaa gatataaaag
     2821 aacctaaaga tttaataggt aaaaaaattg caacagatat gagtgatttc ttatggacaa
     2881 gtgattatgg tccagaaaca ggtctaccaa ctgacccatc aaaatatgaa gttgtaaata
     2941 tggattcaga caaagataaa tatttagctc ttaaaactgg gaaaattcaa gcttttacat
     3001 cttgtgaccc ttggggttct gtagctgaaa atgacggtgc aggaaaaata atagcatcta
     3061 ctcaatataa agaaaaagct aatggcaaag aatataactg ttgttcattc tcattaaaca
     3121 aaaactttat aaaagaacat ccagatttag caaaaaaatt ggttctagca catacaaaag
     3181 caatagaata tatatataca aatccagctg aagcagctaa aatatttgca aaatattata
     3241 atgtagaaga agaagttgca cttagaacta tctataagaa gactgttgga gaaggtagaa
     3301 ctcttacttg gaaagttaca ggtgaagaat ataaaaataa tttacaaatg tataaagatt
     3361 taaaggcttt agatgatata cctaaatatg aagatacgat tgatacaagc ttattggact
     3421 cttgtggagc tgatgatttt gacaaattta taaaagaaaa agttaaccca gagtttcctg
     3481 aaggtatgag ttatgaagac tggaaagcaa aggtattata aataaatgga gaatatgaaa
     3541 aatataataa tactttttat cattattttg ggaagtatat ttataatatt ttttaatttt
     3601 gaagataaag aagaaataaa aggaaaatta agaatagggg tatctgatga tacctctggt
     3661 tttgtaataa attatatggt aaatagagac tactttgaaa atataaaagt aagtgatata
     3721 atggatattt ttacaattaa tgattgctga gcaagtacaa tgcagtgggc tctgagttca
     3781 gaggaaatag atatagcaat catatgtaaa gatgctgcaa aacaatatgt aaatgtaaat
     3841 agtggatttg aaattgttgg tactgtagtt caaaattctg atatatttct attaagtgat
     3901 aataatcctg aaaagatagg agtcattcaa aatagagatt accagtcaga attggttaaa
     3961 aaatactaca agaatgtgga agtagctccc ttattaggga ctgcactagc atatggatta
     4021 gaaagtaatt tagtagatgg tgttgtaata gattgcataa agtcaattgg gttagagggt
     4081 aaaagaaaat ctacaactaa attaggagat tatgatacct atgtattagt tgtaaataaa
     4141 gagtttaaaa aaagtaaagc atatagtgat tttataacac tttacaataa aagtgttgat
     4201 gctttaaaga ataaagctac atttaagaaa gtattaaaag agtacaggaa tataagaaat
     4261 atagatatgg aggaaataag caattggaaa ttaaaatttc taaagataaa agcgatagat
     4321 taactaagaa aaaaactgat ggtagtatgg atattttata taaaataata ctattagtta
     4381 ttatattttt agtctggcat tttgcagcaa aagatatagg gagttctttg ttacttccaa
     4441 tgccagtaga tgtaataaaa ggtttctttt tctgtgtgac agatgcagag acagtcacta
     4501 atctttttat aacattgcag agagtactta aaggttttat gtatgcatta ttgtttgggc
     4561 ttccaatagg atttattatg ggattttcta aaacttttga aagggtttta tctccagtag
     4621 tagattctgt aaggcaagtt ccaataatgg catgggttcc tcttactata gtatggtttg
     4681 gtataggaga tggtccaaca atatttttaa tagctttttc aggggttttc cctataattt
     4741 taaatactat tcaaggagta agagcaatat caaaggatta ttataatgca gctagaagta
     4801 tgggagcatc gccaattgtg atatttacaa atgtaattgt tcccgcatct cttccagata
     4861 tactaactgg ttcaaggatt gctataagta caggatggat gtctgttatc tgagccgagt
     4921 ttatagctac gagtgccggt ctcggttact caatggtaca agctcaaaca ttaatgcata
     4981 cagatgtatt aattgggctt atgatatttg cagctttaat aggatttata atagataggg
     5041 tattaaagtt tataaataaa atcctttgta gatggaggtt tgcagattaa tgaagttaag
     5101 tgtaagagat ataaataaga catttgtaaa taatagagta catacaaagg ttttagaaga
     5161 tataagtatg gatatagatg atggacaatt tgtctgtctt ttaggaccat caggttgtgg
     5221 aaaaacaact ttacttacta taataggtgg gtttcaaaaa tcagaacgtg gagatgtttt
     5281 tataaatgat aaaagagtta aaaaaccggg catagataga gcttttatat ttcaaaatta
     5341 tgctttattt ccttggaaaa ctataagagg taatgttcta tttcctatga aacagcagaa
     5401 aataccaaaa gaaaaaagag aagaaatgct agaagaactt ttggttatgt cagacttgaa
     5461 aggaaaagaa aaactgtttc cgcatcaatt atctggagga atgaaacaaa gagtggccat
     5521 gataagagct ttagcatgta atccagaggt attactaatg gatgaaccat taggagctgt
     5581 agattttcaa atgagacaaa atttacagga agagctagaa cgaatatgga taaagaagaa
     5641 aataactgca ttaatggtaa ctcatgatgt tgatgaagct gtatatatga gtgatagagt
     5701 tatagtaatg tcgagagata aaggaagaat tattgatgat ataaatatag atattccaag
     5761 acctagaatt agaggaagcc aaaaatatga agagtacaaa aacaaattaa ctgatacttt
     5821 atcaaagtgt tatgaagttt aaagaggagt agacatgagt caaatagaaa aatacaatag
     5881 tttggataat acacaacaga aaataagaat ctctattatg gatatgataa tagataaagg
     5941 ttctagtgtt acacttcaag aagtgactga atatgtaagt aaaaagttga atatagaaaa
     6001 agaatatata gaaaggacac tacaatattt tatttataaa aatataatgg ttgttgatgg
     6061 gaatagtata aattttatat atcctgtatc agcattgcca acaaatcata aagtaacttt
     6121 gagagataat agaagtttca gtgcaatgtg tgctatagat gctataggaa cctcttgcac
     6181 attcaaccaa gatataaaaa taaactctat ttgtagtgct acaggtaagg aaatagaagt
     6241 aattataaaa aatgaaaaga ttgagtatgt gaataatcca aacttaagag tgcttcatat
     6301 aaatcttgat aagcatctaa attgggctgc tagttgctga aatataatga atttcttctg
     6361 gacgaagagt gattttgatg cttggacaaa cgaagcggga ttatctgatg atgaagatat
     6421 atattgttta gatattaatg aggcaatagt agaatcatat aaaatattta aactcaaaca
     6481 aaaggtacta tcatagatat acatatatga aaaactaaaa atgaccttta gataaaaatg
     6541 ataggtaata tccatactat ataaattagt atagagtagg gatgtgaaaa gtatttaaat
     6601 ctaaaggtat atttttagtt tttttagatg attagatagc cttattaagt atatatttat
     6661 ttataacctt tgcaactcca ttttcattat tagtatcagt aacataatct gcaatttcct
     6721 ttatactatt acgtgcattc cccatagcca caccaagacc tgcatacttt atcatatgtt
     6781 ggtcattttc ttcatcgcca acagcaatag cattttctat aggtatattt agattcgtac
     6841 ataatgtttt aagagcagtt cctttattag tagttttacc taaaaattct agataaaaag
     6901 gagcagacct tactatagta tatttattga ataaattttt aggtagttgc tgtatgattt
     6961 cttccaatct ttctggttca tcaactatca taattttaca gattttaata gattcatcaa
     7021 ttttatcttt ttgtatatat ttgacttcta tattatttaa tttcgcttca tgaagtgtat
     7081 atttgccagg cgtttcattt ggtgtaatta aatttgtcat tgtatttatg tgtattttag
     7141 tcttatattt tttacaaacg ttattatata taaaatcaaa atcatctaaa ctcatttcta
     7201 catcatgtat gattttctca cttttaactt cttgaataat tgctccatta aagcatataa
     7261 cataatcacc ttcatctgtt aaatttagtt gatttagaag ttcttttaca ccaggaagag
     7321 gtctgcctgt tgttataact acttttgccc cagccctttt tgcctcctga atggactcaa
     7381 agacttcagg agtaatcctt ttttgtgtat ttaatattgt tccatcaatg tctagtgcga
     7441 ttaatttgta catatcaacc tccaataaat tatatactca aatttcctgt gaaaacgttg
     7501 acacagctag tgttgaacaa agtttcagtg ggaaatatgg tttgttttgt atactattat
     7561 atcaagagat aagtaattta gaaagtttaa taatattaat tttttgataa aaatattact
     7621 tatgtgagat gagaatgtaa aaactttgta atcaataatt ccaaaattct taattacaaa
     7681 taatggtatc gtttgcattg ttaatataaa taaatgtata ttatatagtt agaagtttga
     7741 ataaatagac tgatggtaat ttgttatatt agttagtttt gtgttataaa atattgtaat
     7801 tccattaatc atatgttatt attcaacatg attataatat aaagaatatt tgatatatat
     7861 aataatttat aaaagagtat tacatagtac atataaatct atatttataa atacaataaa
     7921 gtaaagttgt aaaggagtgc tttaaatgaa gttttcagag tttaagtatg aaagacccaa
     7981 ttataatagt atgaaaaaag agtttttgag ttgtgtagaa gatataaata attctcgtaa
     8041 ttataaagag caacaaaaaa atatacataa gattaattta ttaagaaata aaatagaaac
     8101 gttgtcaaat atagcttcga taagatatag tacagacaca tttaataaat tctacaaaga
     8161 agaaaaaaat tattgggatg aatatatgcc tttgtatgaa gaattaaatt catattttta
     8221 taatgccatt gtaaattcaa aatttaaata tgatttgata aaagagtttg gagagcaatt
     8281 tttcacaata gtagagtatt ctttaaaaag tttttccaaa gaaataataa gtgaattgca
     8341 ggaagaaaat aaattgtgtt cagagtatac tagactttta gcttcagctg agataatgtt
     8401 tgatgggaaa ataagaaatt tatctggtat ggggaaattc atgtattcta agaatagaaa
     8461 aacaagagaa ttagcaaaca aagcatatta taatttcttt gaagaaaatg aaactaaatt
     8521 tgatgatata tttgataaat tggttaaact tagagataag atgtctaaaa aattaggttt
     8581 tgaagatttt gtagagcttg ggtacattag aatgatgaga agtgactaca gagaatatat
     8641 gataaaaaat gttagaaaac aagtactaaa atatgttgtt ccaatggcaa atgagcttta
     8701 tgaaaaacaa gctaaaagaa ttggtctaga atatttaagt tacatagatg aaggcgtgga
     8761 atttttaaca ggaaatgcaa gtttaaaggg agattcaaga tacataatta aaaatggtaa
     8821 aaggatgtat tctgaactgt caaaagaaac aaatgaattt tttgatttta tgttagaaaa
     8881 tgaacttatg gatttagaaa cgaagaaagg aaaaggagct ggagggtatt gtacttatat
     8941 accagattat aagtcaccat tcattttttc taattttaat caaactgctg atgatataga
     9001 tgtattaaca catgaggcag gacatgcatt tcagttgtat atgtctagat ggattgatat
     9061 gccagaaatt aattttccaa cgcttgatag ttgtgaaatc cattcaatga gtatggaatt
     9121 tataacatgg ccgtggatgg atttattttt taaagaagat acagataagt acaaattcac
     9181 tcacttatca tcttcaatta aatttatacc ttatggagta attgttgatg aatttcaaca
     9241 ctatatttac aaaaatccta atgtagataa gtcaaaacga aaagaaatct ggagattttt
     9301 agagaaaaaa tacttacctc atagaaaata tggtgataat tcttttttag agagaggttg
     9361 ttggtggttt aaacaaggac atatatttaa aaatccgttt tattatatag attatgtatt
     9421 agctcaaatt tgtgcgttac aattttggaa aaaaatgatt caagatagag atgcaggatg
     9481 gaaagattat ataaatatct gtaaagttgg aggaacaaaa tcatttttag atattgtgag
     9541 tatgggaaat ttgtattctc catttgatga tggctgtatt gagtctatta taggtgatgt
     9601 taaatcttgg tttgatgaaa taaatgacag caaattataa aaaattatga gaattttatt
     9661 gtataaaagt aaaaaattaa aaaatatata aaaagtgatt atttgttgtg aaaatagtct
     9721 tgtttttaac taaattgata aaataaacta aaaaagattt gtacttaaaa aaaaaagaaa
     9781 atacaagaaa tatgcaatat caacatttgg aaaaaaaagt aaaaatgtat acaaaataca
     9841 tataaaaaaa ctattgcaaa ttttatagaa tgtttatata cttaagtcaa cagagataga
     9901 aaaaagctat ttatagaaaa caaaggataa attgcttaat tttaaatttt ctgaaaaaaa
     9961 taataatccg gatgaagagt atgggagact gctttataaa aagcgaccga agggacaagt
    10021 ttaatcttac ttacccaaaa gattagatga aattctcagg taaaggtgac tgtacttgga
    10081 cggggctctg aaaatgattt taacagggaa gacaaattgg gagatttgtt tttcctgttt
    10141 tttatttatc aagtaataaa taaaagtttg aaagagagta aaaaaatgat aataattacg
    10201 aataatccaa aagtaaaaga agaagttcaa ggcagagaag ttttgtttaa agacacaact
    10261 tatattggaa tcttagaagc aagtagagat ttgatacatg aaggttatga acttttatct
    10321 catccactct atgggagtgt aaagccaaat gaaacacctt acaggactgt tatactaaag
    10381 aaaggaaatc gtttggatat aaactcttta accttaattg aagaagcaat catcactgca
    10441 agtaaatttc agaataataa aaagactcca aaatggacag aaagtgttca agatgatttt
    10501 agagtaattg attatgatat attttataat acaatacaaa gaatgcagta tgaataaaaa
    10561 aattgttaaa aagttattaa aacagcctaa atattaaatc taatttaata ttaaataaaa
    10621 tgagaaattt aattggggag gataagtcaa aatggaaaat gtgtatgact tagtaataat
    10681 tggttcagga ccagcagggc ttgcagcagg tctttatgga gcaagagcaa agttaaaaac
    10741 tctaatccta gaaaaagaca agactggtgg acaaattgta ataacacatg aaattgcaaa
    10801 ttatccaggg tcagttccaa atgcaacagg accaagttta atagctagaa tggttgaaca
    10861 gtgtaaagag tttggagcag aaatgctaag agacaacatt gttgatactg agctagatgg
    10921 agatataaaa gttttaaaag gggaaaaggc agaatataga gcaaaagcag taataatagg
    10981 aacaggagca acaccaagaa agattggttg tcctggagaa aaagaactta ctggtaaagg
    11041 ggtttcatat tgtgcaactt gtgatgcaga tttctttgaa gattttgaag tatttgttgt
    11101 aggtggagga gacagtgcat tagaagaagc aatgtattta actaaatttg ctagaaaagt
    11161 aacaattgta catagaagac aaggatttag atgtgctaag agtgttgaag aaaaagcaaa
    11221 agctaatcca aagatagagt ttttattaga tacagtaatt gaagaaatca aaggtgatgg
    11281 aatattagaa tcagttgtat ttaaaaataa agttactgga gaaactcatg aatactttgc
    11341 agatgaagaa gatggaacaa tgggagtatt tgtgttcgtt ggattagatg ctcaaactga
    11401 tttattcaaa ggtaaagttg atatggatga aaaaggttac ataataactg atgaagatat
    11461 gagaactaac ataccaggcg tatttgcagc aggagattgt agatctaaga ctctaagaca
    11521 ggttgtaact gcaactaatg atggagcaat tgcatctata gtagctgaga aatacattga
    11581 tgaaaaattt gggaactaga atctgtaaat taagaaatag tgtctgtaaa tttaatgaat
    11641 aatatttaaa attaaaatta atatttaaaa taaaaataaa aatttcaagg gggaataaga
    11701 aaatgttaga tttagataag gctacatttg aagaagaagt tttaaatgca gaaggttttg
    11761 tatttgttga tttttggagt gaaggttgtg agccttgtaa agctttaatg ccagatgttc
    11821 ataaattagc tgagacttat ggggataaaa taaaattctg taagatggat acaacaaaag
    11881 ctagaagatt agctataaaa caaaaagtat taggtcttcc aactatggct atatacaaag
    11941 atggagaaaa agtagacgaa gttactaagg atgatgctac agttcctaat atagaaaaca
    12001 tgattaaaaa atatctttaa tatgttgata aattattaac
//
LOCUS       DAYAOO010000109        11944 bp    DNA     linear   BCT 12-OCT-2024
DEFINITION  TPA_asm: Clostridioides difficile isolate ST8-SSI-h139-18
            SAMN40601845-rid21577343.denovo.110, whole genome shotgun sequence.
ACCESSION   DAYAOO010000109 DAYAOO010000000
VERSION     DAYAOO010000109.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN40601845
            Sequence Read Archive: SRR28438827
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 11944)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11944)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-MAY-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-MAY-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002157583.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002157583.1
            Genome Coverage       :: 163x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/11/2024 16:19:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 4,038
            CDSs (total)                      :: 3,963
            Genes (coding)                    :: 3,930
            CDSs (with protein)               :: 3,930
            Genes (RNA)                       :: 75
            rRNAs                             :: 6, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 60
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 33
            CDSs (without protein)            :: 33
            Pseudo Genes (ambiguous residues) :: 0 of 33
            Pseudo Genes (frameshifted)       :: 7 of 33
            Pseudo Genes (incomplete)         :: 25 of 33
            Pseudo Genes (internal stop)      :: 11 of 33
            Pseudo Genes (multiple problems)  :: 8 of 33
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11944
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN40601845-rid21577343.denovo.110"
                     /isolate="ST8-SSI-h139-18"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Denmark"
                     /collection_date="2018"
                     /collected_by="Statens Serum Institute"
     gene            302..1342
                     /locus_tag="ACGI5H_003404"
     CDS             302..1342
                     /locus_tag="ACGI5H_003404"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424403.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0008134 - transcription factor binding
                     [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sigma 54-interacting transcriptional regulator"
                     /protein_id="HFG9699093.1"
                     /translation="MDKHSDSVMYGGMEVYNIWGTTTVDSIIGESDVMRALKNRICKI
                     GNSDSTVAITGESGTGKELIARAIHLAGNRGNKTFVAINCAAIPEPLLESELFGYTKG
                     AFSGADSKGKIGKFELANGGVVFLDEIGDMPIQLQSKLLRVLQEKKFTRIGSNELIDI
                     DVRIISATNRDLFELVKENKFREDLYYRLNVIPLEVPPLRERGDDIQILINNFIDKYS
                     RKMKKNVYHIEPDVEQMLLKYPWPGNIRELENTIELALNLLEEDGIIHKGIINRKILE
                     YFKLNNINIKLLEESDYEISMEQDILTLEEFERAYIKKVLKFYGNDTKSKKLAAKKLG
                     ISLATLYRKIDV"
     gene            1698..3020
                     /locus_tag="ACGI5H_003405"
     CDS             1698..3020
                     /locus_tag="ACGI5H_003405"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430656.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleobase:cation symporter-2 family protein"
                     /protein_id="HFG9699094.1"
                     /translation="MFDIDGRPPILKCLPLSMQHILAMIVGTVTVPIVVGGAVGVSPT
                     QITLLVQYALIIAGISTLIQLYPIGNIGSRLPIIFGVGFTYVPTLVAVGGNYGLASIL
                     GAQLIGGVATVLIGIFIKKIRKFFPNIVAGTVVFTIGLSLYPIAINYMAGGVNSPTYA
                     SMQNWAVAAITLVVVIGLSQFAKGYAKLAAIFLGIIVGYCVSLVLGIINFDPIREATW
                     FAIPKPLEFGMEFDMPVIISVVIVSIINAVQAIGDLSATTMGGMDRNITDKELSSGVI
                     GSGICTMIGALFGGLPPSSYSQNVGMVAMNKVISRFVLGIAGIFMLLSGFVPKFGALM
                     TTIPYSVLGGATISIFSMITMTGIKLIITEELSSRNITIVGLAIALGMGITSVPAAQE
                     AFPSFVKLVFGESPIVIATLVAFVLNLIIPNKSLEDEAKERAVMEETN"
     gene            3317..4678
                     /locus_tag="ACGI5H_003406"
     CDS             3317..4678
                     /locus_tag="ACGI5H_003406"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729126.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="solute carrier family 23 protein"
                     /protein_id="HFG9699095.1"
                     /translation="MKTRNTSKYDVDGIPPLKESIPLALQHLLAMIVGNMVPAILIAN
                     VVGLNQGQATMLIQGSMLAAGLATFLQLYPIPLFKGFKLGSRLPVMMGMSYVFLGACL
                     SVAAKDGLAALFGAQIAAGVIVFFVGFGVKKIRHIFTPIVSGTIIACMGLGLFATAIK
                     NLAGGEGTQTFGSPINFTVGVIVAFVIIMINKYGKGLVKNSSILIGILVGYAISLVLG
                     LVDFSAVQGAAIVSLPTPAAFGLEFRPELIVMFTIIYIIGIADMMGACTIATVGAMDR
                     EVTDEELASVVLGNSITSIISSLFAALPTGVFSQNTVIVSMNKVTSRFVIALGALVLL
                     LAGISPALGAIMTTIPSCVVGGATLVVFSSIAMSGFSIMSMDGFTEENNLIAGVSIAT
                     SMGLTTAPQVLDQFPETIGTVLGGSSIVSGAIIAILLQTLFKLKSRKSAENVTSNLEE
                     NIG"
     gene            4751..6145
                     /locus_tag="ACGI5H_003407"
     CDS             4751..6145
                     /locus_tag="ACGI5H_003407"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424392.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="amidohydrolase family protein"
                     /protein_id="HFG9699096.1"
                     /translation="MIDILIKNAIIVTVNKDRDVIFDGAIAIQGDRILDIGNTVDIEP
                     KYLDAKKVIDANGKVIFPGFINTHNHLFQVLLKGLGDDMALHEWLNTMMFPSAKFLTE
                     QDTYDAAMLGCMEGLKSGITTMVDYMHTHNRPGLTDGIVKAYKDLGIRGVVGRGCIDL
                     GIHKELIEDVETVEKDLRRVFEKYHNSENGRIKICVAPSSMWAISEEMGKMLWNIVKE
                     YDSYFTVHISETEFARTATKDIHGEIDIKLLEKWGIVGPEVVAVHCVCITDEDMEMLK
                     KYDIKVSHNVASNMYLASGVAPVPEMLKKGINVSLGLDGAASNNAQDMVELMKLTALQ
                     HKVNNCDPLAISAEKVLEMATIEGARTLRMEDEIGSLEIGKKADLVIFNSMLSPKSIP
                     LHNPVSTLVYSASMHNVESVLVDGNVILENGKVTTIESEEQVLLNAQHAAEELCKRAN
                     VTNRMEGHKWNSLY"
     gene            6207..6677
                     /locus_tag="ACGI5H_003408"
     CDS             6207..6677
                     /locus_tag="ACGI5H_003408"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434079.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_function: GO:0051536 - iron-sulfur cluster binding
                     [Evidence IEA];
                     GO_function: GO:0051537 - 2 iron, 2 sulfur cluster binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="(2Fe-2S)-binding protein"
                     /protein_id="HFG9699097.1"
                     /translation="MEKIKLNINDYMYEIEVEKNETLLHVLREKLNLTGAKQGCNSGS
                     CGACKVLIDGVDMKSCKLLAKNCEGKVIYTIESFANGENLHPIQEAFIEVGAVQCGYC
                     TPGMIITTQALLNRNASPNEDEIREAFKENLCRCTGYVKIIEAVKLSAARLGGR"
     gene            6680..8896
                     /locus_tag="ACGI5H_003409"
     CDS             6680..8896
                     /locus_tag="ACGI5H_003409"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902994.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="molybdopterin cofactor-binding domain-containing
                     protein"
                     /protein_id="HFG9699098.1"
                     /translation="MEKVIGKSYPLKDAALKVTGQMKYVADMKPQNVLYAKMLLSPVA
                     HAKIKSIDTSEAEKVVGVRAIATYLNTSQRKYNGSLRFYEHKIPENEVIFSDTVRFVG
                     DRVAAVAAETPEIAEKAVKLIKVEYEELPAVFTIQDAIKEDAICIHGDSNIVSQNNIN
                     GGDVEKGFKECDYIFEDEYSTPAIHHSAIETHSVIAHYDYNDKLTVHTPCQNTFGFRI
                     ILSQIFGMSLNKVRVIRPAIGGSFGGKLELTIEPVAAALSKMTRRPVKMVLTRKESMI
                     STRTRHGSFVKLKTGVNKDGEVIAQDIKIYTNTGAYASSALNVIGALSHKVFKVYKIP
                     NIKFTGMPVYTNTPIAGAMRGYGSPQIFMAQQAQFAKIAKEIGMDLVDFQNKNAVEPD
                     DVDIIFHGSLGNPRVLDCIEQGKKMFKWDEKKKLPKEEGKYLRGIGMAIGAHGNGVFG
                     AHRDVVTLTLKLNEDGTLTLLTGAHDMGNGVVTMQTMMVAEVLGITPDKVDTFETDTD
                     ACTFNLGDYASRGVFVEGGGAKKTAEKLKNLILEEAEKLLETSKEDLYLDNGCVISKL
                     DENVKASLSDVAVYSQSKSLRELTVVEDYSSPAGRTSYGVHFAEVLVDKETKDIKVVD
                     FVAVHDVGRVINPLNLEGQLEGGIHMGLGYALSEELAFDEQGRPKATDFKTYKLFRTV
                     DMPKCQVAFVDGYEKAGPFGGKSIGECAVVPVAPAVANAVYNATDVEIHSLPIKLK"
     gene            8979..9650
                     /locus_tag="ACGI5H_003410"
     CDS             8979..9650
                     /locus_tag="ACGI5H_003410"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424384.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0009055 - electron transfer activity
                     [Evidence IEA];
                     GO_function: GO:0010181 - FMN binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="flavodoxin family protein"
                     /protein_id="HFG9699099.1"
                     /translation="MAKILGICGSPRKGATEYAVLEALKEAETIPGIETEYWSVRGKK
                     ISPCVHCDACIRKETMCIIKDDIQELEQKILEADGIIVGSPVYDMNITAQLTAVFNRL
                     RPMYLVHPGKLQNKVGAAITTGGTRYGGQELTKLPIINFFLMHEMLVSGGLGGCYIGG
                     TIWSKDGKAKGAQEDETGMDTVKRLGKGAAEAVMVSKFGLEKWNVVKEELDVKKDEKS
                     PLRDH"
     gene            10013..11227
                     /gene="dpaL"
                     /locus_tag="ACGI5H_003411"
     CDS             10013..11227
                     /gene="dpaL"
                     /locus_tag="ACGI5H_003411"
                     /EC_number="4.3.1.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890217.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008838 - diaminopropionate ammonia-lyase
                     activity [Evidence IEA];
                     GO_function: GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="diaminopropionate ammonia-lyase"
                     /protein_id="HFG9699100.1"
                     /translation="MLKEIKWKVNNLPKGDKENCIKFLNEEEITKVRNFHKSFPQYKE
                     TPLANLEGLAKKLGVAGVYVKDESYRFGLNAFKVLGGSYSMGRYLAQRLDTDISELGY
                     DKLTSKEIKEKLGEITFFTATDGNHGRGVAWTANKLGQKSVVLMPKGSSEFRLNKIKG
                     EGADASITDLNYDDAVRLANDYAEADDHGVMVQDTAWDGYEEIPAWIMQGYGTMAQEA
                     IEQLKEYGVDRPTHVFVQAGVGSLAGAVQGYVASIYDECPITVVVEADEADCYYKSAE
                     AGDGKPRFVGGDMPTIMAGLACGEPNTIGFEVLKNHAAAFVSAPDWVSAKGMRTLGNP
                     LNGDEKVISGESGAVTTGLLVAAMEREDLADLRKDLKLDENSRILLISTEGDTDPDKY
                     RSIVWDGEYPSI"
     gene            11354..>11944
                     /locus_tag="ACGI5H_003412"
     CDS             11354..>11944
                     /locus_tag="ACGI5H_003412"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893427.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="M20/M25/M40 family metallo-hydrolase"
                     /protein_id="HFG9699101.1"
                     /translation="MLNEQRKQEVTEICQKLIQNPSSSGNEEGVVKAIEESFEKLGFD
                     SWSRDRYGNIVGCIKGNKPGKKILFDGHIDTVPVPDASKWSVPPFEGKIVDGKIYGRG
                     TSDMKGQYTAMMSAVAYFAKDTNRDFAGELYVAGVVHEEIFEGVSAREISKAVQPDYV
                     VIGESSELNLKIGQRGRGEIVVETFGKPAHSANPEKG"
BASE COUNT         4527 a         1362 c         2412 g         3643 t
ORIGIN      
        1 agtaatttta tataggtata aaaattacga gtagtataaa aaatttaata agaacttaaa
       61 ttaaaaattt taaaaattat ttccatataa aatatggcat tgtaattgct tatttaatag
      121 aggatttttg taaaatgaag aaagtatatc tatcaaatta aaactaagta gatatacttt
      181 ttattaagtt ttgttttaaa ataatattat taaattataa ctaagctttt ctgttatgat
      241 ataattaaat agataatgtg aatgattatt atatagaata cttatttgga gttgatattt
      301 tatggacaaa cacagtgatt cagtaatgta tggtggaatg gaagtatata atatttgggg
      361 aacaacaaca gtagactcca taattggaga gtctgatgta atgcgtgctc ttaagaatag
      421 aatttgtaaa attggaaata gtgattctac tgtagctata actggagaaa gtggcactgg
      481 aaaagaatta atagcaagag ccattcatct cgcaggaaac agagggaata aaacattcgt
      541 tgctataaac tgtgctgcta taccagaacc tttactagaa agtgaacttt ttggatatac
      601 aaaaggagct tttagtggag cagattcaaa aggtaaaatt ggtaagtttg aattggccaa
      661 tggaggggtt gtatttttag atgagatagg agatatgcca attcaactac aatcaaagtt
      721 attgagggta ttacaggaaa agaagtttac gagaataggt tcaaatgaac taattgatat
      781 agatgttaga atcatatcag ctactaatag agatttattt gagttggtta aggaaaataa
      841 atttagagaa gacttatact atagattgaa tgtaatacct ttagaagtgc ctccacttag
      901 agaaagagga gacgatatac aaatattaat aaacaatttt atagacaaat attcgagaaa
      961 gatgaagaaa aacgtgtacc atatagagcc agatgtggaa caaatgttgc ttaagtatcc
     1021 ttggccagga aatattagag agttggaaaa tactatagaa ctggcattaa accttcttga
     1081 ggaagatgga ataatacata aaggaataat aaatagaaag atacttgaat attttaagtt
     1141 aaataatata aatataaagt tacttgagga aagtgactat gagataagta tggaacaaga
     1201 catacttaca cttgaagagt ttgaaagagc ctatataaag aaagtgttaa agttttacgg
     1261 aaatgatact aagtctaaaa aactagctgc caaaaaactt ggaatatcac tagctacatt
     1321 gtacagaaaa atagatgtat aataattagg ctttttattc tcaattctaa aatttgaaat
     1381 tataaaattg ataaaaaaca cttggaaaac tattttctaa gtgttttttt gtgtaatagc
     1441 attttattat ccaaaaataa aaaaaattta aaagaattta aaaaaataaa tgctttaata
     1501 aattatcaaa tactaacaaa tataataaaa attatatatg taaaacaatt atgttaaaaa
     1561 attggcatta taattgcttc atattaagtt gagatgacaa aataaaaaaa gaaaggatgt
     1621 tgtgtgagat aataataact gtcattaaaa aatagttggg agtgataacc ttgagtaaat
     1681 atcaaaagaa tgtttctatg tttgatattg atggaaggcc accaatttta aagtgtttgc
     1741 cactatcaat gcaacatata ctagcaatga tagttggaac tgttacagta cctatagtcg
     1801 taggaggagc tgtgggtgtt agccctacac aaataacact tttagtgcaa tatgcattaa
     1861 taatagctgg tatatcaaca cttatacaac tatatccaat aggaaatatt ggttcaagat
     1921 tgcctataat ttttggagtt ggttttactt atgtaccaac acttgtagca gtcggaggaa
     1981 attatggatt agcaagcatt ttgggtgcac aattaatagg gggagtggct acagtattaa
     2041 tagggatatt cataaaaaag ataagaaaat tttttccgaa tatagttgca ggaacagtgg
     2101 tttttacaat tggattatct ttgtatccta tagcaataaa ttatatggca ggtggtgtaa
     2161 atagtcctac ttatgcctct atgcaaaact gggcagtagc ggctataaca ttagtggtag
     2221 ttataggtct tagtcaattt gcaaaaggat atgcaaaatt ggcagcaata tttttgggaa
     2281 ttatagttgg atattgtgta tctttagttc tgggtataat aaattttgac cctattagag
     2341 aggcaacttg gtttgcgata cctaaaccgc ttgaatttgg gatggaattt gatatgcctg
     2401 taataatctc agtagtaatt gtaagtataa tcaatgctgt tcaagcaatt ggagatttat
     2461 cagctactac aatgggaggc atggatagga atatcacaga taaggaatta tcaagtggag
     2521 taataggaag tggaatttgt actatgatag gagctttgtt tggaggttta ccaccatcat
     2581 catatagcca aaacgtgggg atggtagcta tgaacaaagt aataagtaga tttgtgcttg
     2641 gaatagctgg tatatttatg ttattgtcgg ggtttgtgcc taaatttggt gcactaatga
     2701 ctactatacc atattctgtt ttaggaggag ctacaatatc tatatttagt atgataacaa
     2761 tgacaggtat aaagttaatt attacagaag agttgtcatc aagaaatatt accattgttg
     2821 gtttggcaat tgccttaggc atgggaataa catcagtacc agcagcccaa gaggcatttc
     2881 cttcatttgt aaagttagta tttggagaat ctccaatagt aattgcaaca ttggttgcat
     2941 tcgttttaaa tctaataata ccaaataaaa gtctagagga tgaggctaaa gaaagagctg
     3001 ttatggaaga gactaattaa gatataataa tttaaaagaa ttgtttaaat tatttagtat
     3061 gagattgtta gattattttt gatagctatt cattttaata aaaaatttaa caaataaata
     3121 tataccaggc aattaatgtt catttaagtt gaaaatcggg gagggaatat ttagaaattt
     3181 gttaattttt tataaaaata gctcagttta gctgtgttta tcggttgagc aataaattca
     3241 tggtcataaa aatatttata gaaaataatt ataaaaatat ttagtcaaga tatttatgta
     3301 tgggaggatt tattttatga aaacacgtaa tacttcaaaa tatgatgtcg atgggatacc
     3361 accactaaag gaatcaatac ctttggcctt acaacatctg ttagcaatga tagtaggaaa
     3421 tatggtacct gcgatattaa tagcaaacgt ggtaggactt aaccaggggc aagcaacaat
     3481 gttgattcag ggttctatgt tagcagcagg tttagcaacg tttttacagt tatatccaat
     3541 acctttattt aaaggattta agttaggttc aagattacct gtaatgatgg gaatgagtta
     3601 tgtattttta ggagcttgtc tttcagtagc agctaaagat ggtttagcag ctctatttgg
     3661 agcacagatt gctgctgggg taatcgtatt ctttgtagga tttggagtta agaaaattag
     3721 acatatattc actccaatag tttctggaac tataatagca tgtatgggac ttggactatt
     3781 cgcaacagct ataaagaatt tagctggagg agaaggcaca caaacatttg gaagcccaat
     3841 aaacttcaca gtaggagtta tagttgcttt tgtaataata atgataaata aatacggtaa
     3901 aggtttagta aaaaattctt caatattaat aggaatatta gtaggttatg ctatatcttt
     3961 agttttagga ttggttgatt tctcagccgt tcaaggagca gctatagtat ctttaccaac
     4021 accagcagct tttggattag aatttagacc agagttaata gtaatgttta ctattattta
     4081 cataataggt atagctgata tgatgggtgc ctgtacaata gctacagtag gagcaatgga
     4141 tagagaggta actgacgaag aattagcatc agttgtttta ggaaattcta taacttctat
     4201 aatttcatca ctatttgcag ctcttccaac tggagtattt agccaaaata cagtaattgt
     4261 atctatgaac aaagttacaa gtagatttgt aatagcacta ggggcacttg tattattact
     4321 agcagggata tctccagcat tgggtgcaat aatgacaact ataccatctt gtgttgttgg
     4381 tggagcaact ttagtagttt tctcatcaat agcaatgtct ggtttctcta ttatgagtat
     4441 ggatggattc actgaagaaa acaatcttat agcaggtgta tctatagcaa caagtatggg
     4501 tcttacaact gctccacaag ttttagacca attcccagaa acaattggaa ctgtccttgg
     4561 agggtcaagt atagtttctg gagcaataat agctatatta cttcaaacat tatttaaatt
     4621 aaagtcacgt aaaagtgctg aaaacgttac ttcaaatctt gaggaaaata ttggataaat
     4681 gtattagata taatatgaga aaaccatatg gtaaaatgtt gtaatgaaag tattcaaagg
     4741 gggatttaag atgattgata tactaataaa aaatgcaata attgttacag ttaataaaga
     4801 cagagatgtt atatttgatg gagcaatagc tattcaaggt gacagaatct tggacatagg
     4861 aaatacagtt gatattgagc ctaagtatct tgatgctaaa aaagttatag atgctaatgg
     4921 aaaagtaata ttccctggct ttataaatac tcataatcac ctgttccaag tgttattaaa
     4981 aggtttaggt gatgatatgg cacttcatga gtggttaaat acaatgatgt ttccatcagc
     5041 aaaattctta acagaacaag atacttatga tgctgcaatg cttggatgta tggaaggttt
     5101 aaaaagtggt ataactacaa tggttgatta tatgcatact cacaatagac caggacttac
     5161 agatggaata gtaaaggcat ataaagattt aggtataaga ggggttgtag gtagaggttg
     5221 tatagattta ggtattcaca aagagcttat agaagatgtg gaaacggttg aaaaagattt
     5281 gagaagggta ttcgaaaaat atcataattc agaaaatgga agaataaaaa tctgtgtagc
     5341 tccttcttca atgtgggcta tatctgaaga aatgggtaag atgctttgga atatagttaa
     5401 agaatatgat tcatatttta cagttcatat atctgaaaca gaatttgcaa gaacagcaac
     5461 aaaggatata catggagaaa tagatataaa attacttgaa aaatggggta tagtaggtcc
     5521 agaagttgta gcagtacatt gtgtatgtat aactgatgaa gacatggaaa tgcttaaaaa
     5581 gtatgacata aaagtttctc ataatgtagc aagtaacatg tatcttgctt ctggtgttgc
     5641 acctgtgcca gaaatgttaa aaaaaggtat aaatgtgagt ttaggtcttg acggtgcagc
     5701 aagtaataac gcacaagata tggtagagct tatgaaatta acagctttac aacacaaagt
     5761 aaataattgt gaccctctgg caatttctgc agagaaagtt cttgaaatgg ctacaattga
     5821 gggagcaaga actcttagaa tggaagatga aataggttct ttggagattg ggaaaaaagc
     5881 tgacctagta atatttaact caatgctttc tccaaaatca atacctcttc acaatcctgt
     5941 atcaactttg gtatactcag ctagtatgca caatgtagag agtgttttag ttgatggaaa
     6001 tgtaatactt gaaaatggaa aagtaactac aattgaaagt gaagaacaag tgttgcttaa
     6061 tgcacaacat gcagcagaag aattatgtaa gagagctaat gtaactaata gaatggaagg
     6121 acataagtgg aatagcttat actaatatta aaataagatt gtaataatat tctattacaa
     6181 cattagttta tctgtaggag gagaaaatgg aaaaaataaa attaaatatt aatgattaca
     6241 tgtatgaaat agaagttgaa aagaatgaaa ctcttttgca tgtacttcgt gaaaaattaa
     6301 atctaactgg agcgaaacaa ggttgtaata gtggcagttg tggagcatgt aaagttttga
     6361 tagatggagt tgacatgaaa tcttgtaaac ttcttgcaaa aaactgcgaa ggtaaagtta
     6421 tatacactat agaaagtttt gctaatggag aaaatcttca tccaatacaa gaagctttta
     6481 tagaagtcgg agctgtacaa tgtggatatt gtactcctgg tatgattata acaacacaag
     6541 ctcttttaaa tagaaatgca tctcctaatg aagatgaaat tagagaagct tttaaagaaa
     6601 atctctgtag atgcacagga tatgtaaaga ttatagaagc tgtaaaatta tctgcagcta
     6661 gattaggggg tagataatta tggaaaaggt aataggaaaa tcataccctc taaaagatgc
     6721 agctttaaaa gttactggtc aaatgaaata cgtggctgat atgaaaccac aaaatgtact
     6781 ttacgctaag atgcttttaa gccctgtagc acatgcaaaa ataaaaagta tagatacaag
     6841 tgaagctgag aaagtagtag gtgttagagc tatagctact tatctcaata catcacaaag
     6901 aaaatacaat ggttcattaa gattttatga gcacaaaata cctgaaaatg aagttatatt
     6961 ttcagataca gttagatttg ttggtgaccg tgttgcagca gtagctgcag agactccaga
     7021 aatagcagag aaagctgtaa aacttataaa agttgaatat gaagaattgc cagctgtatt
     7081 tactatacaa gatgcaataa aagaagatgc tatctgcata catggagatt caaatatagt
     7141 ttctcaaaac aacataaatg ggggagatgt agaaaaaggc ttcaaggaat gtgattatat
     7201 atttgaagat gaatactcta ctccagcaat acatcatagt gcaatagaga ctcatagtgt
     7261 aattgcacac tatgattata atgataaatt aactgtacat acaccttgcc aaaatacatt
     7321 tggatttaga ataatactat ctcaaatttt tgggatgtca ttaaataaag taagagttat
     7381 aagacctgct attggaggct catttggtgg aaaattagaa cttacaattg aaccagtagc
     7441 agccgcatta tcaaaaatga caagaagacc agttaaaatg gttcttacaa gaaaggaatc
     7501 tatgatatca acaagaactc gtcatgggtc ttttgtaaaa ttaaaaactg gtgtaaataa
     7561 agatggtgaa gtaatagcac aagacataaa aatatataca aatacaggag catatgcatc
     7621 aagtgcttta aatgttatag gagcacttag tcataaagta tttaaagttt ataaaatacc
     7681 aaatataaag tttactggga tgcctgtata tacaaataca ccaatagcag gagctatgag
     7741 aggctatggg tcacctcaaa tatttatggc tcaacaagct caatttgcga aaatagcaaa
     7801 ggaaataggt atggatttag tcgattttca aaataaaaat gcagtagagc cagatgatgt
     7861 cgatataatc ttccacggtt ctcttggaaa tcctagagta ttggattgta tagagcaagg
     7921 taagaagatg tttaagtggg atgaaaagaa aaaacttcca aaagaagaag gaaaatattt
     7981 aagaggtata ggtatggcaa taggtgcaca tggtaatgga gtttttggtg cacatagaga
     8041 tgttgttaca ttgactctta aattaaatga agatggtacg ttgacactac taacaggagc
     8101 tcatgatatg ggtaatggtg ttgtaactat gcaaacaatg atggtagctg aagttttagg
     8161 aataacacct gataaagttg atacatttga aactgatacg gatgcatgta cattcaacct
     8221 tggtgactat gcaagtagag gggtatttgt agaaggtgga ggagctaaaa agacagcaga
     8281 gaaattgaaa aatcttatat tagaagaagc agaaaaatta cttgaaacat caaaagaaga
     8341 tttatatcta gacaatggat gtgtaattag taaacttgat gaaaatgtaa aagcatcact
     8401 ttctgatgtc gcagtatata gtcaaagtaa atcattaaga gagttaactg ttgttgaaga
     8461 ttattcttca ccagctggac gtacttctta tggtgtacat tttgctgaag ttttagtaga
     8521 taaagaaact aaggatataa aagtagttga ttttgtagct gtacatgatg ttggtagagt
     8581 tataaatcct ctaaatttag aaggacaatt agaaggtggg attcatatgg gtctaggata
     8641 cgcattgagt gaagaattgg catttgatga acaaggtaga cctaaagcta ctgattttaa
     8701 aacatataaa ttatttagaa ctgtagatat gccaaaatgt caagttgcat ttgtagatgg
     8761 ttatgaaaaa gctgggcctt ttggtggtaa gagtattgga gaatgtgccg ttgtaccagt
     8821 tgcgccagct gttgcaaatg cagtatataa tgcaactgat gtagagatac attcattacc
     8881 aataaaatta aaatagtaga aattaaagca gaaataacaa tttattgtat ttgtaaatag
     8941 ataataaaaa tagatttatt tggtgaggag atattattat ggcaaagata ttaggtattt
     9001 gtggaagtcc acgtaaagga gcaacagaat atgcagtgtt agaagctttg aaagaagcag
     9061 aaactatacc tggtatagaa actgagtatt ggtcagttag agggaaaaaa ataagtcctt
     9121 gtgtacattg tgatgcatgt ataagaaaag aaactatgtg tattataaaa gatgatatcc
     9181 aagaattaga gcaaaaaata ttggaggcag atggaattat agtaggttct ccagtttatg
     9241 atatgaatat aactgctcaa cttacagcag tatttaatag acttcgtcca atgtatttag
     9301 ttcatccagg aaaacttcaa aataaggttg gtgcagctat aactactggt ggaactagat
     9361 atggtggcca agaattgaca aaacttccta taataaattt cttcctaatg catgaaatgt
     9421 tagtgtctgg aggtttaggt ggatgctata taggtggtac aatatggagt aaagatggaa
     9481 aagcaaaagg tgcccaagag gatgagacag gtatggacac agtaaaaaga cttggaaaag
     9541 gtgcagcaga ggcagttatg gtttctaagt ttggtcttga aaaatggaat gtcgtaaaag
     9601 aagaattaga tgttaaaaaa gatgaaaaat cacctcttag agaccactaa agatttatta
     9661 tattattgaa tatatacaaa tagtgatgta atagattatt gcatcactat tttatgtttt
     9721 aatttagatt ttataaattt tatattaaaa aatatagaaa caaagtgttt tgagatttat
     9781 ttttaaattt taaaaatgag aattaaaaag tgagaagata gaaaaggttt tttagttatt
     9841 aaattctaca tacattgtat gaactaaaga tagaaaagaa aaaataataa aagcattgca
     9901 atttctatac taaagagtca tggaaaaata tctagtatat atttagtatt ggcatgttaa
     9961 ttgcttatat attaaagtat aaaaatttaa caataatttg gaggtatttt agatgttaaa
    10021 agaaattaaa tggaaagtaa ataatttgcc aaagggcgat aaggaaaatt gtatcaaatt
    10081 tttaaatgaa gaagaaataa ctaaggttag aaattttcac aaaagctttc ctcaatataa
    10141 agaaactcca ttagcaaacc tagaaggttt agcaaaaaaa ttaggtgttg caggagtata
    10201 tgtaaaagat gaatcttata gatttggatt aaatgcattt aaagtattag gtggttctta
    10261 ttctatgggt agatacttag ctcaaagatt agatacagat atatctgagt tagggtatga
    10321 caaattgact tcgaaagaaa taaaagaaaa attaggagaa ataactttct ttacagctac
    10381 agatggaaat cacggtagag gagttgcttg gacagctaat aaattaggtc aaaaatctgt
    10441 tgtattaatg ccaaaaggtt cttctgaatt tagattaaat aaaattaaag gagaaggtgc
    10501 agatgctagt ataacagact taaattatga tgatgcagta agattagcta atgattatgc
    10561 agaagctgat gaccatggag taatggttca agatacagca tgggacggat atgaagaaat
    10621 accagcatgg ataatgcaag gatatggaac tatggctcaa gaagctatag agcaattaaa
    10681 agaatatgga gtagatagac caacacacgt atttgttcaa gcaggagttg gttcacttgc
    10741 tggtgcagtt caagggtatg ttgcttcaat atatgatgaa tgcccaataa cagtagtagt
    10801 agaggctgat gaagctgatt gttactataa atcagcagaa gctggagatg gaaaaccaag
    10861 atttgttgga ggagatatgc caactataat ggcagggctt gcttgtggag agccaaatac
    10921 tataggattt gaagtattaa aaaatcatgc agcagcattt gtttcagcac cagactgggt
    10981 ttctgctaaa ggtatgagaa cattaggtaa tcctttaaat ggtgatgaaa aggtaatttc
    11041 tggagaatct ggagcagtta caactggtct tttagtagca gctatggaaa gagaagattt
    11101 agcagattta agaaaagatt taaaattaga tgaaaattca agaatacttt taataagcac
    11161 agaaggagat actgaccctg acaaatatag aagtatagtt tgggatggag aatatccaag
    11221 tatataagga attactaaaa tgcaattatt agatattggt ttacatattt agaagatata
    11281 taagttctaa aatttagaaa atatataagt atataaaata catacattat aaaaaatcta
    11341 gggggataat gaaatgttaa acgaacaaag aaaacaagaa gtaactgaaa tatgccaaaa
    11401 attaattcaa aatcctagtt cttctggaaa tgaagaaggt gttgtaaaag caatagaaga
    11461 gtcttttgaa aaattaggtt ttgatagttg gtcaagagat agatatggaa atatagtagg
    11521 atgtataaaa ggtaacaagc caggtaagaa aatattattt gatggacata tagatacagt
    11581 tccagttcca gatgcaagta aatggagtgt tcctcctttt gaaggaaaaa tagttgatgg
    11641 aaagatatat ggtagaggaa cttctgacat gaaaggtcaa tatactgcaa tgatgtctgc
    11701 tgtagcgtat tttgctaaag acactaatag agattttgct ggagaactat atgtagcagg
    11761 tgttgttcat gaagaaatat ttgaaggtgt ttcggctaga gagataagta aggctgttca
    11821 acctgactat gttgtaatag gtgagtcttc agagttaaac ttaaagattg gtcagagagg
    11881 tagaggagaa atagtagtag aaacttttgg taaaccagct cactctgcta atccagaaaa
    11941 aggt
//
LOCUS       DAYAOO010000110        11888 bp    DNA     linear   BCT 12-OCT-2024
DEFINITION  TPA_asm: Clostridioides difficile isolate ST8-SSI-h139-18
            SAMN40601845-rid21577343.denovo.111, whole genome shotgun sequence.
ACCESSION   DAYAOO010000110 DAYAOO010000000
VERSION     DAYAOO010000110.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN40601845
            Sequence Read Archive: SRR28438827
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 11888)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11888)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-MAY-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-MAY-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002157583.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002157583.1
            Genome Coverage       :: 163x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/11/2024 16:19:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 4,038
            CDSs (total)                      :: 3,963
            Genes (coding)                    :: 3,930
            CDSs (with protein)               :: 3,930
            Genes (RNA)                       :: 75
            rRNAs                             :: 6, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 60
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 33
            CDSs (without protein)            :: 33
            Pseudo Genes (ambiguous residues) :: 0 of 33
            Pseudo Genes (frameshifted)       :: 7 of 33
            Pseudo Genes (incomplete)         :: 25 of 33
            Pseudo Genes (internal stop)      :: 11 of 33
            Pseudo Genes (multiple problems)  :: 8 of 33
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11888
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN40601845-rid21577343.denovo.111"
                     /isolate="ST8-SSI-h139-18"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Denmark"
                     /collection_date="2018"
                     /collected_by="Statens Serum Institute"
     gene            135..803
                     /locus_tag="ACGI5H_003413"
     CDS             135..803
                     /locus_tag="ACGI5H_003413"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside recognition domain-containing
                     protein"
                     /protein_id="HFG9699102.1"
                     /translation="MSKLESTTEKVEVKWYGYVALILGALFFSGIFKDAPGPLKVLDF
                     NNVLGSFGTLGTINDGVGTLAANFRGDGGTGPRDGWLYALTLIPSVMFALGVVRVIDH
                     LDGMKAAQKLLSPLLKPLLGLPGFAGLTLIASLQSTDAAASMTKELKDDGYIDEKQKA
                     VFCAFQFSGASAITNFFASGAALFPFIGDVPIFIPLALILIMKFVGANLLRLYLNKFD
                     KGEA"
     gene            805..1290
                     /locus_tag="ACGI5H_003414"
     CDS             805..1290
                     /locus_tag="ACGI5H_003414"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004455006.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YjiG family protein"
                     /protein_id="HFG9699103.1"
                     /translation="MSEVAKKEVKVKKGNVIDAFIGGARNGFQISTNSMAPNVIFGFA
                     IISVFNLTGLLDVIGTIFTPVMSIFGLPGVAATAIMTIFISMGGASGVIAGLFTAGQI
                     SQAHVAILLPMLLLSGAQIQFMGRLLGTAELKTKYYPHMFVIATLNGCIAMLIMNYFV
                     V"
     gene            1351..2472
                     /locus_tag="ACGI5H_003415"
     CDS             1351..2472
                     /locus_tag="ACGI5H_003415"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890931.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M20 peptidase aminoacylase family protein"
                     /protein_id="HFG9699104.1"
                     /translation="MGTNKDYIEYVHKVYDYLHTIPEKGFEEYKTSEFVLKELEKMGF
                     ENINKGVAGTGIIVTIDSKKEGPVFAIRADMDALEFIIDGEKKMIHACGHDGHTSMLL
                     TAAKLIKERNLVKRGKLKILFQPGEEKLYGALRVIDSGLLDDVEEMVGMHLRPGQDCR
                     LGKAIPAMYHCASCIMEFTIKGITCHGSKPHLGVNAVDAVCLAVNAINAIRVNPAIPN
                     SIKVTNISVKGETYNNIPDEAFMALDIRAESNDIIEELKEKAIHAVKTVVSSINAEAV
                     LISKDGVPAAEFDEELVNLAEETIKDVLGADASIGIFKNSGGEDFHYYTQKLKCKTTY
                     IGLGADATPGFHNPNVTFDTKALEYGVDIWCRLVEKRLG"
     gene            2753..3943
                     /locus_tag="ACGI5H_003416"
     CDS             2753..3943
                     /locus_tag="ACGI5H_003416"
                     /EC_number="4.4.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728658.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA];
                     GO_function: GO:0047804 - cysteine-S-conjugate beta-lyase
                     activity [Evidence IEA];
                     GO_process: GO:0009086 - methionine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MalY/PatB family protein"
                     /protein_id="HFG9699105.1"
                     /translation="MSKYNFDRVIDRVGTDCVKWDFRTNCSTKAQKDGLPFWIADMDF
                     ECAEPIIEALRKKVEHKIFGYSSNDSDKYFNAVCDWYKRRFNWEISRKDIIFSPGVVP
                     AVAILVRILTNSNEGVIVQKPVYYPFEAKIKSNNRDVVNNPLIYENGTYRMDYDDLEE
                     KAKCSNNKVLILCSPHNPVGRVWREDELKKVVEICKKYDLWIIADEIHSDLIRKGFKH
                     TPLQSLCPEYKDKIVTCIAPSKTFNLAGMQLSNIIVNNDELKKKYQEEVTAVGVATSP
                     NPFAIVATIAAYNESEDWLNELNDYLDNNIQFIDEYLKENLPKVKLVYPEGTYLAWLD
                     FTAYGLNEVELEDLMFKKANVLFDEGYIFGKEGIGFERINVACPQSLLKECMDRLKTI
                     FENL"
     misc_binding    4077..4332
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            4391..5392
                     /gene="asnA"
                     /locus_tag="ACGI5H_003417"
     CDS             4391..5392
                     /gene="asnA"
                     /locus_tag="ACGI5H_003417"
                     /EC_number="6.3.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427105.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0004071 - aspartate-ammonia ligase
                     activity [Evidence IEA];
                     GO_process: GO:0006529 - asparagine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate--ammonia ligase"
                     /protein_id="HFG9699106.1"
                     /translation="MSTIIPKDYKSSLNVIDTQIAIKKLKDFFEMRLSNELNLIRVSS
                     PLFVLPETGANDNLNGEKAVSFDIPFMNKNAEIVQSLAKWKRLALKKYGFEVGSGLYT
                     DMNAIRKNEELDNIHSLYVDQWDWELVIDKSSRNEKTLKDVVKRLYGVFKDTEIFVCS
                     MYEGIKEILPEEITFITSQELEDMYPELSPKEREDKIVKEKKAVFITQIGKTLISGEK
                     HDGRSPDYDDWELNGDILFYNPVLDSALELSSMGIRVDEESLDRQLKLAGCEERKEFD
                     YHKMLLNGELPYTIGGGIGQSRICMYFLQKAHIGEVQVGVWPQDMIQNCSSAGIELL"
     gene            5496..5885
                     /locus_tag="ACGI5H_003418"
     CDS             5496..5885
                     /locus_tag="ACGI5H_003418"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004455003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1232 domain-containing protein"
                     /protein_id="HFG9699107.1"
                     /translation="MEFLKIIINIVLDILKKILVRFKNAKFGLVFVFDLLKLPDFMTD
                     KRINIVDKIKVISVLIFTISYFVSGVDIIPEMIAGAFGFIDDAIVLIWSIGIVNEEIN
                     KYRVIAKKDKHSNIIENVEFSIKDEEE"
     gene            6046..7254
                     /locus_tag="ACGI5H_003419"
     CDS             6046..7254
                     /locus_tag="ACGI5H_003419"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893711.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dicarboxylate/amino acid:cation symporter"
                     /protein_id="HFG9699108.1"
                     /translation="MKKKIGLVPKLIIGIIVGILIGSYAPEIIVQILVTVSTLFSAFL
                     KFVIPFIIIGFVTAGIADLATGAGKLLGITTGIAYGSTLIAGLLSFAVSTLIFPNFID
                     ASVASQIGDPEAGMLAPIFTIPLEPMVDVTAAIVFAFVMGLGISALRNHGKGETLFNF
                     FQEFQGIVTKTLSTVIIPLLPLYIAGTFANITIAGEVWTILGVFWKVYLVVIPLHFVY
                     MACQFTAAGVFSGKNPVRMLKNQVPGYLTAIGTQSSAATIPVNVGCAEKNGVSKQIRE
                     FVVPLCATIHLSGSMISITGFTTAVLMMNGMPHGIGVLFPYIAMLGIAMVAAPGAPGG
                     AIMSALPFLPMVGIPSDGGLASLMIALYLTQDSFGTACNVSGDNAIAVVVDKINDGMS
                     KKGNKEEQSA"
     gene            complement(7340..8416)
                     /locus_tag="ACGI5H_003420"
     CDS             complement(7340..8416)
                     /locus_tag="ACGI5H_003420"
                     /EC_number="2.6.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003415975.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004400 - histidinol-phosphate
                     transaminase activity [Evidence IEA];
                     GO_function: GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA];
                     GO_process: GO:0000105 - L-histidine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="histidinol-phosphate transaminase"
                     /protein_id="HFG9699109.1"
                     /translation="MSTNHGANLYSLSSKYGFSKEEFMDFSSNINPFGTSSLAKQYIV
                     NNIDMVSMYPDPDYIDLKTSISNYCKCSIDNIVLGSGATELISSFIHTINPKQALLLS
                     PAYSEYEKELSKINCSIEKYFAKEEDNFHINLENLIKTINAKDYDLVVICNPSNPTGF
                     AFTKVEVREILKNTDSFLMIDETYVEFTDTDTYSCTQLVDDYSNLFVIRGTSKFFSTP
                     GIRLGYGLISNTNVKNEINKNLDLWNINIIASKMGEIMFSDLDFISNTISLMNTERDY
                     LLKELKNIKSLDIYNTKGNFILCKIKTKELTAKSLREQLLPQKIIIRDCCSFEGLDEY
                     FFRVCILKPNENKLLISSLKAIFK"
     gene            8645..9172
                     /gene="hpt"
                     /locus_tag="ACGI5H_003421"
     CDS             8645..9172
                     /gene="hpt"
                     /locus_tag="ACGI5H_003421"
                     /EC_number="2.4.2.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416006.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0006166 - purine ribonucleoside salvage
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="hypoxanthine phosphoribosyltransferase"
                     /protein_id="HFG9699110.1"
                     /translation="MYKVTGKMLTEEQIKEKVYELGKKIEEDFKGEDLLVVGILKGAS
                     VFVSDLIRCIDLDVNIDFMSVTSYGNSTESSGTVKILKDLDVDIEGKNVLIVEDIIDS
                     GLTLSNLVAALKTRNPKSLKLCTLLDKPQRRKANIPVDYVGFVIEDKFIVGYGIDYAE
                     KYRNLPYIGIVEDVE"
     gene            9261..10193
                     /locus_tag="ACGI5H_003422"
     CDS             9261..10193
                     /locus_tag="ACGI5H_003422"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897871.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatase PAP2 family protein"
                     /protein_id="HFG9699111.1"
                     /translation="MDIQLNILLFFQNLRNPILNFIFLVFTISTEAPLLILITTIIYW
                     CINKKCGQKILFAIIGNFVVNLGIKEFVKAPRPIGIKGLESLRVSTAGGYSFPSAHTQ
                     TATTFWVSIMTIFKKRYLHLIGAVMVLGVGLSRLYLAVHWPIDVIAGWILGIFFTVVF
                     VKIFDYIDDNKNYILLVVLLIPFIIVAIFLNSPEYFEKFGIIVGFVFGYMVEDRFVKF
                     NTDNNNKKINFSNKNKGSKNIIFSRICRFLVGIVTIGMLYIGIKLFISMLIVTLNISD
                     STMSIIFMNFIKNTVVVFYGIAGAPALFKLLKLN"
     gene            10255..11481
                     /locus_tag="ACGI5H_003423"
     CDS             10255..11481
                     /locus_tag="ACGI5H_003423"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427089.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="HFG9699112.1"
                     /translation="MKKVVIIGGGPAGMIAASTACEKGYDVTLIEKNHKLGKKLAITG
                     KGRCNITNACEIEELIENVPTNGKFLYSAFYTFTNDDVISMFNNLGVKTKTERGKRVF
                     PESDKAFDIVNALERQLKSKKVNILLNSKVEKIISKNNKIEKVILNDKKEIKCDSVVV
                     ATGGLSYPLTGSTGDGYKFAISQGHTIIDTKPSLIGIEVQESFTKDLEKLSLRNVEIR
                     VFNSKQKKVYSDFGELEFTKFGLDGPIIKSASCRMKDTRKENYTILLDLKPALDEEKL
                     DKRVQKDFQKYTNKKFEKALDDLLPKKLIPIIINLSEINPNTVVHQISREQRKNLVHL
                     LKNLKFTVKRYRPIEEAIITSGGVKVNEINSSTMESKLVEGLFFAGEVIDIDAYTGGF
                     NLQIAFSTGYLAGFNC"
     gene            11565..11786
                     /locus_tag="ACGI5H_003424"
     CDS             11565..11786
                     /locus_tag="ACGI5H_003424"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416009.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003690 - double-stranded DNA binding
                     [Evidence IEA];
                     GO_process: GO:0006265 - DNA topological change [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="small, acid-soluble spore protein, alpha/beta
                     type"
                     /protein_id="HFG9699113.1"
                     /translation="MASNNNNNRTVVPGAKEALNQMKLEIANELGMSNYQQVDKGNLT
                     ARENGYVGGYMTKKLVEMAEQQMAGKSNR"
BASE COUNT         4602 a         1253 c         2161 g         3872 t
ORIGIN      
        1 agctatttaa tcactggaat aaatttacaa taaaaaaata aatacaaagg ctttatcatt
       61 aaggtattgg cataagtttt gcttattaaa caagtatact aataaaattc atttaaacag
      121 gagggagaat ttatatgagt aaattagaat caacaacaga aaaagttgag gtaaaatggt
      181 atgggtatgt agcattaata ttgggagcat tatttttttc aggaatattt aaagatgcac
      241 caggaccatt aaaagtattg gattttaaca atgtattagg ttcttttgga acattgggaa
      301 caattaatga tggtgtaggt acattagctg caaactttag aggtgatgga ggtactggcc
      361 ctcgagatgg atggctatat gcattgacat taataccatc agttatgttt gcacttggag
      421 tagttagagt tatagaccac ttagatggaa tgaaggcagc tcaaaagctt cttagtccac
      481 tattaaagcc attattaggg ttacctggat ttgcaggact aactttgata gctagtttac
      541 agtctacaga tgcagctgca tctatgacta aagaacttaa agatgatggg tatatagatg
      601 aaaaacaaaa agctgtattt tgtgcatttc aattttcagg tgcgtctgca attacgaatt
      661 tctttgcttc tggagcagca ctatttccat ttataggaga tgtaccaata tttataccac
      721 ttgctttaat attaattatg aagtttgttg gggcgaactt acttagatta tatttaaata
      781 aatttgacaa gggggaagct taacatgagt gaggtagcaa aaaaagaagt aaaagttaaa
      841 aaaggaaatg tgatagatgc gtttattgga ggagctagaa atggattcca aataagtaca
      901 aattcaatgg ctccaaatgt catcttcggt tttgctataa tttctgtgtt caacttaaca
      961 ggtcttttgg atgtaatagg gacaatattt acacctgtaa tgagtatctt tggacttcca
     1021 ggtgttgcag caacagctat aatgacaata tttatatcaa tgggaggagc atctggagta
     1081 atcgcaggtt tatttacagc aggtcaaata agtcaagcac atgttgcaat tctattgcca
     1141 atgttattgc tttcaggagc gcagatacaa tttatgggga gacttttagg aacagctgag
     1201 ttaaaaacta aatattatcc acatatgttt gttatagcaa ctttaaatgg ttgtattgca
     1261 atgcttataa tgaattattt cgtagtatag gtaattataa taaaaattta atataaatgg
     1321 aaagtttaaa ttttaaggag gagctagatt atgggaacta acaaagatta tattgagtat
     1381 gtacataaag tgtatgatta tctacacact ataccagaaa aaggatttga agaatataag
     1441 acatcagagt ttgttttaaa agagcttgaa aaaatggggt ttgaaaatat taataaagga
     1501 gttgcaggaa ctggtattat agtaactata gattctaaaa aagaaggacc agtatttgct
     1561 ataagagcag atatggatgc attggaattt atcatagatg gagaaaagaa aatgatacat
     1621 gcttgtggtc atgatggtca tacttctatg cttttaacag ctgcaaagtt aataaaagag
     1681 agaaatttag taaaaagagg taagttaaaa atactttttc aaccaggtga agaaaaatta
     1741 tatggagcat taagagtaat tgattctggt ttgttggatg atgtagaaga aatggtaggg
     1801 atgcatttaa gacctggaca agattgtagg ttgggaaagg cgatacctgc aatgtaccat
     1861 tgtgctagct gtataatgga atttacgatt aaaggtatca cttgtcatgg ttctaaacca
     1921 catttaggag taaatgcagt agatgctgtc tgtttagcag tgaatgcaat aaatgcaata
     1981 agagtaaatc cagctatacc aaattctata aaagtaacaa atatatcagt taagggagaa
     2041 acttataata atataccaga tgaagcattt atggctttag atataagggc agaaagtaat
     2101 gatataatag aagaattaaa agaaaaagca atacatgctg taaaaactgt tgtaagttct
     2161 ataaatgcag aagctgtact aatttccaaa gatggagtac cagcagcaga atttgatgaa
     2221 gaacttgtaa acttggctga agaaactata aaagatgtat tgggagctga tgcatctata
     2281 ggtatattta aaaattctgg tggagaagac ttccattatt atacacaaaa actaaaatgt
     2341 aaaactacat atattggatt aggagctgat gctacaccag gatttcataa tccaaatgta
     2401 acatttgata cgaaagcttt agaatatggt gtagatatat ggtgtagatt ggttgaaaag
     2461 agattgggat aacatccaaa ctaataattc tacatttaaa attataatta tagaagttat
     2521 agaaaaagat tgcttatgtt aattagaaaa taattaatat gagcaatctt attttgatat
     2581 aatgaaactg attttggaat attgaaaaaa tatgatggaa aagtaattat attttaaatc
     2641 tattggacaa aaaagtgata ttattataat attaagaatt gtaaaataat accaaagtgc
     2701 atctagtaat agacttaaca attataaaaa ttttattctt aggagggaaa aaatgagtaa
     2761 gtataatttt gacagagtaa tagatagagt aggaacagat tgtgtaaaat gggattttag
     2821 aactaattgt tcaacaaaag cacaaaaaga tggtttgcct ttttggattg ctgatatgga
     2881 ttttgaatgt gcagaaccaa taatagaagc attacgtaaa aaagttgaac ataaaatatt
     2941 tggatatagt tcaaatgata gtgataaata ctttaatgca gtttgtgatt ggtataaaag
     3001 gagatttaac tgggaaataa gtagaaaaga tattattttt agtcctggtg ttgtacctgc
     3061 tgttgctatt ttagtaagaa tattaactaa ttctaatgaa ggtgtaatag tccaaaaacc
     3121 agtgtattac ccatttgaag ctaagataaa gagcaataat agggacgttg taaacaatcc
     3181 tctgatatat gagaatggta cttataggat ggattatgat gatttagaag aaaaagctaa
     3241 gtgtagcaac aataaagtac taatactttg tagtcctcac aaccctgttg gaagagtttg
     3301 gagagaagat gaattaaaaa aggttgtaga aatatgtaaa aaatatgacc tatggataat
     3361 agctgatgag atacattctg atttaattag aaaaggattt aaacatactc ctttacagtc
     3421 attatgccca gagtacaagg ataaaatagt tacatgtata gctccaagta aaacatttaa
     3481 tctggcagga atgcagttgt ctaatataat agtgaataat gatgaactaa aaaagaaata
     3541 tcaagaagag gttacagctg ttggagttgc aacttcacca aatccctttg ctattgtagc
     3601 tacaatagca gcatataatg aaagtgaaga ctggcttaat gaattaaatg attacttaga
     3661 taataatata caatttattg atgaatactt aaaagaaaac ctaccaaaag taaaacttgt
     3721 ttatccagaa ggaacatatc tagcatggtt agattttact gcttatggat taaatgaagt
     3781 agaacttgaa gatttaatgt ttaaaaaagc taatgtatta tttgatgaag gttatatatt
     3841 tggaaaagaa ggaataggat ttgaaagaat aaatgtagct tgtccacagt ctttattaaa
     3901 agaatgtatg gacagattaa agactatatt tgaaaattta taaagtatag gtaaaaattt
     3961 ataaagtgtt taaaaataaa aaaataataa acttgacaaa ttttaactaa tcacttatca
     4021 tactattatg aataaataga aaacataaga gagctaaatt ttattgaatt aaactcttaa
     4081 agactttgaa aggaagagta gttatagaat gtaattaaag cgagttggtg atggtgtgag
     4141 accaatatga agtctatagt gaagaacatc ctggagttgc taaccgaaat tttaaaagag
     4201 taggcttagt cggaaccaaa ccgttatcat attggggtgt atcgagtaat atctgtacat
     4261 tgtgagctgg gtttgaattt atttcaaact aatcagggtg gtaccgcgga aaagcaacct
     4321 ttcgtccctt ttatataggg atgaagggtt tttttaatgg aaaaatatat aaatataggg
     4381 agtgaatgat atgagcacaa taataccaaa ggattataaa agtagtttga acgtaattga
     4441 tacacaaata gctataaaaa aattaaaaga tttttttgaa atgagactaa gtaatgaatt
     4501 aaatcttata agagtttctt ctccgttatt tgtattgcca gaaacaggtg caaatgataa
     4561 tttaaatgga gaaaaggctg taagctttga tataccattt atgaataaaa atgcagaaat
     4621 tgttcaatca cttgcaaaat ggaaaagatt agcccttaaa aaatatgggt ttgaagttgg
     4681 tagtggttta tatacagata tgaatgcaat aagaaaaaat gaagaattag acaatataca
     4741 ttctctttat gtagaccaat gggattggga attggttata gataaaagta gtagaaatga
     4801 aaagactcta aaagatgttg taaaaagatt gtatggagta tttaaagata ctgaaatttt
     4861 tgtatgtagt atgtatgaag gtataaaaga aatattacca gaagaaataa cttttataac
     4921 atcacaagag ttagaagata tgtatccaga attatcacca aaggaaagag aagataaaat
     4981 tgtaaaagag aagaaagcag tatttataac tcaaatagga aaaacattaa tatcaggaga
     5041 aaaacatgat ggaagaagtc ctgattatga tgattgggaa ttgaatgggg atatattatt
     5101 ttacaatcct gttttagatt cagcattaga attatcttca atgggaatta gagttgatga
     5161 agaatctctt gatagacaat tgaaacttgc tggatgtgaa gagagaaaag agtttgacta
     5221 tcataagatg cttttaaatg gcgaacttcc gtatacaatt ggtggaggaa ttggtcagtc
     5281 aagaatatgt atgtatttct tacaaaaagc tcatatagga gaagtacaag ttggagtatg
     5341 gccacaggat atgattcaaa attgtagtag tgcaggaatt gaattattat aatttaaata
     5401 taaactaatt gataaaattt atatctaata tgttcatcaa attaattata tcggttataa
     5461 tgtagaataa cctataatta taagaggtga taaatatgga gtttttaaaa ataatcatta
     5521 atatagtttt agatatttta aaaaaaattt tggtcagatt taaaaatgct aaatttggtt
     5581 tggtttttgt atttgattta cttaaactac ctgattttat gacagataaa agaatcaata
     5641 tagttgataa aataaaggta atttctgtat taatttttac tatatcctac tttgtatctg
     5701 gggttgatat aattccagag atgattgcag gggcatttgg ttttatagat gatgctatag
     5761 ttttaatttg gagtataggt atagtgaatg aagaaattaa taagtataga gttatcgcaa
     5821 aaaaagataa acattcaaat ataattgaaa atgtagaatt ttctataaaa gatgaagaag
     5881 aataacaatt tatatatgtt attctttttt ttattaacaa aaaatggtta aattgttgac
     5941 ggagaggtaa aactctatta tcataataag tggatatcca atatttaact aagtattcaa
     6001 tgtgcaagaa tgcttaattt aaaaaagtta tggagggtaa atattatgaa gaaaaaaata
     6061 ggtttagtgc ccaaactaat catcggtatc atagtcggta ttttaatcgg aagttatgca
     6121 ccagaaataa tagtacaaat attagtaaca gttagtactt tattctcagc attcctaaaa
     6181 tttgttatac catttataat tataggtttt gtaacagcag gtatagctga tttagcaaca
     6241 ggtgcaggaa agttattggg gataactacg ggaatagcat atggttctac cttaatagca
     6301 ggattattat catttgcagt atctacatta atcttcccaa attttattga tgcaagtgtt
     6361 gcaagtcaaa ttggagaccc agaggcagga atgttagctc caatattcac aattccatta
     6421 gagcctatgg tagatgtaac agctgcaatc gtatttgcat ttgtaatggg acttggaata
     6481 tcagctttaa gaaatcatgg aaaaggagag actttattta atttcttcca agaatttcaa
     6541 ggaatcgtaa cgaaaacgtt gtcaacagtg attatacctt tattaccttt atacatagca
     6601 ggaacttttg caaatataac tatagcaggg gaagtatgga caatattagg ggtattctgg
     6661 aaagtatact tagtagtaat acctttacat tttgtatata tggcatgtca attcacagca
     6721 gcaggtgtat tttcaggaaa aaatccagta agaatgttaa aaaatcaagt acctggatat
     6781 ttaacagcta taggaactca atcttcagca gcaactatac cagttaatgt tggttgtgca
     6841 gaaaaaaatg gagtaagtaa gcaaataaga gaatttgttg tacctctttg tgcaacaata
     6901 catttatcag gtagtatgat atcaataaca ggatttacaa ctgcagtttt aatgatgaat
     6961 ggtatgccac atggaatagg tgtattattc ccttatattg caatgttagg tatagcaatg
     7021 gttgcagcac caggagcacc aggtggggct ataatgagtg cacttccttt cctaccaatg
     7081 gttggaatac catcagatgg tgggcttgca agtttaatga tagctttata cttaactcaa
     7141 gacagttttg gtacagcatg taatgtatca ggagataatg caatagcagt agtagtagat
     7201 aaaataaatg atggaatgag taaaaaagga aataaagaag agcaaagtgc ttagtttttt
     7261 aataatcaaa aatgagttat ctcaaataga gatagctcat tttttatggt ataaaaaatt
     7321 ataaaataaa gtgatttttt tatttaaaaa ttgctttaag agatgatatt aataatttat
     7381 tttcattagg ttttaatata catactctaa agaaatactc atctagacct tcaaatgaac
     7441 aacaatctct tattattatt ttttgtggaa gcagttgctc tcgaagagat ttagcagtca
     7501 attcctttgt cttgatttta cacaatatga aattaccttt agtattgtat atatctaagc
     7561 tttttatatt cttaagctct ttaagcaggt aatctctttc agtgttcatt aaggaaatag
     7621 tatttgatat aaaatctaaa tcactaaaca tgatttcacc cattttagaa gctattatgt
     7681 ttatattcca taaatctaga tttttattta tttcattttt gacattagtg ttagatataa
     7741 gaccatatcc aagccttatt ccaggcgttg aaaaaaattt tgatgtacct cttataacga
     7801 ataaattaga ataatcatca actaattgag tacaagagta tgtatctgta tcagtaaact
     7861 ctacataagt ctcatcaatc attaaaaatg agtctgtatt ttttaaaatt tctctcactt
     7921 ctactttagt aaatgcaaat ccagttggat tactaggatt acagattact accaaatcat
     7981 aatctttagc attgatagtt tttataagat tttctaaatt tatatgaaaa ttatcttctt
     8041 cttttgcaaa gtatttttct atagaacaat taattttaga taactctttt tcatactctg
     8101 aataggctgg agagagtaaa agagcctgtt tagggttaat tgtatgtata aatgatgaaa
     8161 ttagttctgt agctccactg ccaagtacta tattatctat agaacatttg cagtaattgg
     8221 atatagaagt ttttaagtct atgtaatcag ggtcaggata catagatacc atatctatat
     8281 tgtttacaat gtattgtttg gctaaacttg atgtaccaaa aggatttata tttgagctaa
     8341 aatccataaa ttcttccttt gaaaagccat acttactaga taaactatat aaattagctc
     8401 catggtttgt gctcataaaa gtacctccaa aaataaaatt atataatcga taaaaataac
     8461 tgattaatat atgtacatat agattataat acaaaggaat cgttattcca aatttttaat
     8521 gtaaaaagca aaaaagtatg gataagctgt taatttaggt ttaaaaatga tgaaaaagat
     8581 tttaattgat attttggtat gctataatat ataagttaat agaaggaaag cgggaggata
     8641 caaaatgtac aaagttacag gaaaaatgtt gacagaagaa caaataaaag aaaaagttta
     8701 tgaattagga aaaaagatag aagaagactt taaaggcgaa gatttactag tggtaggtat
     8761 acttaaagga gctagtgtat ttgtttcaga tttaataaga tgtatagatt tggatgtaaa
     8821 tatagatttt atgagtgtta caagttatgg aaactcaaca gagtcttctg gaacagttaa
     8881 aatattaaaa gatttagatg tagatattga aggaaagaat gtgttgattg tagaggatat
     8941 aatagattct ggtttaacat taagtaatct agttgcagct ttaaaaacta gaaatccaaa
     9001 atctttaaaa ctatgtactc tacttgataa acctcagaga agaaaagcta atatacctgt
     9061 agactatgtt ggatttgtta tagaagacaa atttattgtt ggttatggaa tagactatgc
     9121 tgaaaagtat agaaatttac cttatatagg tatagttgag gatgtagaat agatttaaat
     9181 gtgaatcaaa agcactaatt tctaagggag ttagtgcttt ttagttaatt atataaaatt
     9241 ttagtaaagg agacatctat atggatattc agttaaatat attattattt ttccaaaatt
     9301 taagaaatcc aattttgaac tttatatttc ttgtctttac aataagcaca gaagcaccgt
     9361 tattaatatt aattacaaca attatatact ggtgtataaa taaaaaatgt ggacagaaaa
     9421 tactgtttgc tataattgga aattttgttg taaatttagg catcaaagag tttgtaaaag
     9481 ctcccagacc aataggaata aaaggtcttg aatcattgag agtttctact gctggtggtt
     9541 attcttttcc aagtgctcat actcaaactg caacaacatt ttgggttagt attatgacta
     9601 tatttaaaaa gagatatctt catttaatag gtgcagttat ggttttagga gtaggattgt
     9661 ctaggctgta tttagctgtt cattggccaa tagatgtgat agcgggttgg atattaggaa
     9721 tattttttac agttgtattt gtaaaaatat ttgactatat tgatgataat aaaaattata
     9781 ttttacttgt agttttactt ataccattta taatagtggc tatatttcta aatagccctg
     9841 aatattttga aaaatttggt ataatagtag gatttgtatt tggatatatg gttgaggata
     9901 gatttgttaa atttaataca gataataata acaaaaaaat aaattttagc aataaaaata
     9961 aggggagtaa aaatataatt ttttcaagaa tatgtaggtt tttggttggg atagtaacaa
    10021 taggaatgtt atatattggc attaagttgt ttatttcaat gttaatagtc actttaaata
    10081 taagtgactc tactatgagt ataattttta tgaattttat taagaataca gtagttgttt
    10141 tttatggaat agcaggagct ccagcattat ttaaactttt aaaattaaat tgattttaag
    10201 gtatagagtc aatagtttaa attaaaaaaa ttaagggtag aaaagagtga ttatttgaag
    10261 aaggtagtaa taataggtgg tggaccagca gggatgatag ccgcatcaac tgcatgtgag
    10321 aaaggctatg atgtaacatt aattgagaaa aatcataaat taggaaaaaa acttgcaata
    10381 acaggaaaag gtagatgtaa tattactaac gcttgtgaaa tagaggaatt aatagaaaat
    10441 gtacctacaa atggaaaatt tctttatagt gctttttata cttttacaaa tgatgatgta
    10501 ataagtatgt ttaataatct tggagtaaag actaaaacag aaagaggaaa aagggttttt
    10561 ccagagagtg ataaagcatt tgatattgta aatgctcttg aaagacaact taaaagtaag
    10621 aaagtaaata tattattaaa ttcgaaagta gaaaaaataa tatctaaaaa taataaaatt
    10681 gaaaaagtaa ttttaaacga taaaaaagaa attaagtgtg attcagttgt agtagcaact
    10741 ggtggattaa gttatccact tactggttct actggtgatg gatataaatt tgcaatttca
    10801 caggggcaca caattataga tacaaaacca tctttaattg gtatagaagt acaagaaagt
    10861 tttacaaaag atttagaaaa attatcattg agaaatgttg aaataagggt gtttaatagc
    10921 aaacaaaaga aagtttatag tgattttgga gaacttgaat ttactaaatt tggtttagat
    10981 ggacctataa tcaagtctgc aagttgtaga atgaaagata caaggaaaga aaattacact
    11041 atattattag atttaaaacc tgcattagat gaggaaaaat tggataaaag agttcaaaaa
    11101 gattttcaga agtatacaaa taaaaaattt gaaaaagcat tagatgattt acttccaaaa
    11161 aaactaatac ctataataat aaacttaagt gaaattaatc caaatacggt tgttcaccaa
    11221 atttctagag agcagagaaa aaacttagtc catttattaa aaaatttaaa gtttacagta
    11281 aagagataca gacctattga agaagctata ataacttctg gtggtgtaaa agtaaacgaa
    11341 ataaattcaa gtacaatgga atcaaaatta gtagaaggtt tattttttgc tggagaagta
    11401 atagatatag atgcatatac aggtggattc aatttgcaaa tagctttttc tactggatat
    11461 ttggcaggtt ttaattgcta aaaattacct gaattaaaaa tgtttaaaat cacataatat
    11521 tatcagcaac acaaaataaa ttaaacagaa ggaaggtaat caacatggca agtaacaata
    11581 acaacaacag aacagtagta ccaggagcaa aagaggcttt aaaccaaatg aaattagaaa
    11641 tagctaatga acttggtatg agtaattatc aacaagttga taaaggaaac cttactgcaa
    11701 gagaaaatgg ttatgtaggt ggatacatga ctaaaaaatt agttgaaatg gctgaacaac
    11761 aaatggctgg aaaaagcaac agatagttat aaataattat ttataactat tggctattag
    11821 tttagctaga gctatctcaa atatagaaag taatttctaa attgagatag ctttttttta
    11881 ttaaatta
//
LOCUS       DAYAOO010000111        11463 bp    DNA     linear   BCT 12-OCT-2024
DEFINITION  TPA_asm: Clostridioides difficile isolate ST8-SSI-h139-18
            SAMN40601845-rid21577343.denovo.113, whole genome shotgun sequence.
ACCESSION   DAYAOO010000111 DAYAOO010000000
VERSION     DAYAOO010000111.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN40601845
            Sequence Read Archive: SRR28438827
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 11463)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11463)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-MAY-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-MAY-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002157583.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002157583.1
            Genome Coverage       :: 163x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/11/2024 16:19:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 4,038
            CDSs (total)                      :: 3,963
            Genes (coding)                    :: 3,930
            CDSs (with protein)               :: 3,930
            Genes (RNA)                       :: 75
            rRNAs                             :: 6, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 60
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 33
            CDSs (without protein)            :: 33
            Pseudo Genes (ambiguous residues) :: 0 of 33
            Pseudo Genes (frameshifted)       :: 7 of 33
            Pseudo Genes (incomplete)         :: 25 of 33
            Pseudo Genes (internal stop)      :: 11 of 33
            Pseudo Genes (multiple problems)  :: 8 of 33
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11463
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN40601845-rid21577343.denovo.113"
                     /isolate="ST8-SSI-h139-18"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Denmark"
                     /collection_date="2018"
                     /collected_by="Statens Serum Institute"
     gene            complement(157..321)
                     /locus_tag="ACGI5H_003425"
     CDS             complement(157..321)
                     /locus_tag="ACGI5H_003425"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424195.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9699114.1"
                     /translation="MFGKPKESVRFLDFNDVAEKFGEKKAVAIFDAIAGKKSKEHIIK
                     DIEKLVKNEV"
     gene            complement(863..1195)
                     /locus_tag="ACGI5H_003426"
     CDS             complement(863..1195)
                     /locus_tag="ACGI5H_003426"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435227.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0051920 - peroxiredoxin activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="carboxymuconolactone decarboxylase family
                     protein"
                     /protein_id="HFG9699115.1"
                     /translation="MNTREMKEYRGFYNKKLSETDEFFRVFGSLDDKTYSEGAISKKN
                     KELMGLAISILSRCDECICYHIEGCINSGASKDEIIEAIKIGVIGGGSITYPNARFAI
                     KILEEFNI"
     gene            complement(1439..2080)
                     /locus_tag="ACGI5H_003427"
     CDS             complement(1439..2080)
                     /locus_tag="ACGI5H_003427"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435225.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SdpI family protein"
                     /protein_id="HFG9699116.1"
                     /translation="MKKAINKQFILSTLICFIPFIVSIYFYNRLPNEVAIHFDNYGNP
                     DNYAPKVIAAFGVPLLMLCIHLYTWFRLENEPKKANFSNVIQNLSKWGVAILSVIIQI
                     MMVLYSTGVSLESNFYTGLILGIIVILFGNYLPKCKRNYSVGIILPWTLNDEDNWNKT
                     HHLAGWIWLIGGILLIINAFINIPFYNIFVIFVIVILPFIYSYLMYKISGKNN"
     gene            complement(2061..2354)
                     /locus_tag="ACGI5H_003428"
     CDS             complement(2061..2354)
                     /locus_tag="ACGI5H_003428"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889969.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="autorepressor SdpR family transcription factor"
                     /protein_id="HFG9699117.1"
                     /translation="MGFPETFKALSDPIRREILVMLRENKMSAGEISEKFNMTNATIS
                     YHLSQLKKAGLIFETKYKNFIFYEINISVFEEVMLWFSQFMEKGEKDNEKSDK"
     gene            2735..2806
                     /locus_tag="ACGI5H_003429"
                     /pseudo
     CDS             2735..2806
                     /locus_tag="ACGI5H_003429"
                     /inference="COORDINATES: protein motif:HMM:NF024729.4"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_process: GO:0015074 - DNA integration [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
     gene            complement(2977..3111)
                     /locus_tag="ACGI5H_003430"
     CDS             complement(2977..3111)
                     /locus_tag="ACGI5H_003430"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433020.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9699118.1"
                     /translation="MNISRRAMKIIELAQKIANKRGVTVQDAWNDAMKEYKEKYEYVA
                     "
     gene            complement(3322..4074)
                     /locus_tag="ACGI5H_003431"
     CDS             complement(3322..4074)
                     /locus_tag="ACGI5H_003431"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861417.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sulfite exporter TauE/SafE family protein"
                     /protein_id="HFG9699119.1"
                     /translation="MFSVIFLCIGGFLAAFVDSIAGGGGLISMPVLMAIGVPVHLAIG
                     TNKFAASAGCISSAYRYAKSGKINNNLLKKLVPFTIIGSVLGVRCVLSISEEILNVLV
                     VVMILIVAIYTFISKNLGQEDNFEAVNKKNLRLGMLMALIMGFYDGFFGPGTGTFLTF
                     GFIKIYGYDFLHASANTKILNLTSNITSLLLFMINGQVDYKIAIVFALVMIMGAYVGA
                     KVAIKKGSKMIKPIFLVMALFMVVKLVYQTLV"
     gene            complement(4133..5788)
                     /locus_tag="ACGI5H_003432"
     CDS             complement(4133..5788)
                     /locus_tag="ACGI5H_003432"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729413.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_function: GO:0043565 - sequence-specific DNA binding
                     [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HFG9699120.1"
                     /translation="MEYFSESNNEVQKFDWGEVMWIHEPSKTQFNRLSAGIVRFFPGN
                     YQEKHFHLSEEQLLYVIQGEGIQIIDGKKVNIKETSIVYCPPYSEHEIINTGKIDLVI
                     LITYVPHKFSSLRQIPIVFSENNIQELVNVNIIENLANQISNILKLRISVYDLKYKEI
                     FETKKENKFCDICKNIKQCTKKLVKSINNDNFEKVYHCEYGVSSLEIPIVLEENIVGY
                     IECGNFIVYKSIDIDKNLSELSSSSGIDIKYINKIYNEFPLNPKSRLYVLKENLLMMS
                     EFIQEIAKRNFFENQLSIKDEEILKSRKENIRLEEALKKANSRLLEEEYIINPIDMFN
                     NSSKEYPFELELYIEKEIKNMNLEGVYNLIDTNKLRYNDVRDTIQEMIFVLSRTVLRD
                     LEDLKLISYLRNKYNKKISLVNSDEDLWNVLFEFSKECIDKNRAFWRKDKGNLIENIN
                     EYIKKYYKENINLNSISDVFFISPNYLSSIFNERNKVSITEYINLLRIEESKKYLLDR
                     SMSISDICKKVGFNNSSYFSQIFKKFNSITPNEYRKNMLDNKY"
     gene            complement(7061..8140)
                     /locus_tag="ACGI5H_003433"
     CDS             complement(7061..8140)
                     /locus_tag="ACGI5H_003433"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897145.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HFG9699121.1"
                     /translation="MILITLCILVAVFVLAFAGLRLIAPTIIRTSHKIEAPGIDRMEM
                     VEIGGIQQALYIRGQNADNPIILWVHGGPGNSMMPFLHLYQYEWENDFTVVNWDQRNV
                     GKTYFANDPAAVLQTMSAERVLQDVHEVTAYLKQEFNKEKIILIGHSWGTVLGTMAVQ
                     TYPEDYSAYIGIAQTVNMVDNERVGYEKTLEMVKAAGKQKDIKALEAIAPYPPAKYGP
                     SYLAALMTVRTYQSKYGLSINMDLGNIISILATPYYSLRELKNTAIFNPNAIDNQGDV
                     LRFLVEEADIRNYGVDYQVPVYYIMGENDYNSPYLPAKKFFDEIVAPDKQIFFIPDAD
                     HLPFLSKKAEFDCVLLEEIAPKLAK"
     gene            complement(8224..8880)
                     /locus_tag="ACGI5H_003434"
     CDS             complement(8224..8880)
                     /locus_tag="ACGI5H_003434"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861420.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HFG9699122.1"
                     /translation="MTRKNNPKQAIENIITISAKLFAEKGYDKTSMQNIVDASGMSKG
                     GIFHHFSSKEDIFNVVMERRFEQIIETVNQWLGEMHGLTAKEKLRSLVRRHLTDEVIK
                     ESSNMITSAIESPHIILAFTQDNLKKLAPILANVLREGIEDRSIITEFPDECAEVILL
                     LFNFWCDTDVFQGDFPTLRKRFQFLQFLMRQIGVDILEDEIIESINIFYERKPMGQVE
                     "
     gene            9202..9408
                     /locus_tag="ACGI5H_003435"
     CDS             9202..9408
                     /locus_tag="ACGI5H_003435"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435216.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9699123.1"
                     /translation="MISHAAEICKKYKMPFIIFPTIEKKSIEEWVNIGANMLCLAQDT
                     TFITYVINQLLSFYNEIVPIQKQH"
     gene            complement(9561..9989)
                     /locus_tag="ACGI5H_003436"
     CDS             complement(9561..9989)
                     /locus_tag="ACGI5H_003436"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018112846.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0010181 - FMN binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="flavodoxin"
                     /protein_id="HFG9699124.1"
                     /translation="MSKIYIVYWSGTGNTEKMANFVAEGVKLKGKTPEVLDVSLLKPS
                     DLKEEDKFALGCPSMGAEQLEEGYMEPFVSELESMVSGKQIGLFGSYGWGNCEWMRDW
                     EERMQNAGATIIGGEGITAMEDPNEEAKDECIELGKTLAE"
     gene            complement(10465..11403)
                     /locus_tag="ACGI5H_003437"
     CDS             complement(10465..11403)
                     /locus_tag="ACGI5H_003437"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889978.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S8 family peptidase"
                     /protein_id="HFG9699125.1"
                     /translation="MNKRMKLIPYEINENLRGAKNKFPYGIKQMNARGMWDEGYTGKN
                     IVVGIIDTGCDISHPLLKGKIIGGANFSDDSNGNKNIYEDFNGHGTHVAGIIAASNYN
                     NEVMGVAPDCKLLIAKALNKDGTGTYQSIINAINFAVNNKVDIISMSLGGNKDDKNLK
                     NAVMQAVKNNISVVCAAGNNGDGDSSTSEYSYPASYAEVIEVGAINENYLVEKFSNSN
                     TTIDLVAPGRNIISTYMDNKLAIMSGTSMSAPYVSGSLALIKEWAREEFERDLDEAEL
                     YAQLIKCTRALGIPRTEQGNGYLYLNLYKYKNNSKR"
BASE COUNT         3861 a         2012 c         1181 g         4409 t
ORIGIN      
        1 taaactaatt acaagtttaa attataaaga cttatttcta tataaatatt actctataac
       61 aataagtttc ttatttaaat tttaaaatat tatctaaaaa tcataaaaaa gaaggtataa
      121 agagctaccc tcaagctcaa tataccttat aaatatctaa acttcatttt ttactaattt
      181 ttctatatct ttgataatat gttctttaga tttttttcca gctatggcat caaaaattgc
      241 aacagccttt ttctctccaa acttttctgc tacatcatta aagtctaaaa atctaacact
      301 ttcttttggt ttaccaaaca tataacacct ctcatacatt tttatatatt tattataact
      361 tctatagact tatttttcac caataaacgt tagacaaatt agtcccttta tttttttaaa
      421 ctagctttac cttcaaaatt cttaacaaaa acagtttatt ctactctata aataaaaata
      481 gacaatttaa tttgtaggaa actgataata gaatacagta aataaaactt tgtttaatct
      541 atctgaaaaa gttatctatt aaaactgcta tgaatttata aagaatattc tagttcataa
      601 aaatacaaat atgtaaatat aatcacctta atattcaatt tatttaaaat aaaaaatgta
      661 taaaagattt aataatgaca atatactatt ctcaatacaa tctatgatgt aaataattta
      721 aaactactat attatttaaa aatttatatt tatatatgca attctaaaaa cttaataaga
      781 agtgaactta gaaaataaag cttaatttca aagacttaaa tagactatta ttattagtct
      841 aaataaacta cgtctatcaa aattatatat taaattcttc taaaattttt attgcaaatc
      901 ttgcgtttgg atatgtaata gacccgccac caattacacc tatttttata gcttctataa
      961 tttcatcttt acttgctcca gaattaatac aaccctcaat atgataacaa atacactcat
     1021 cacatcggct taaaattgaa atagctagtc ccattaattc cttatttttt ttgcttatag
     1081 ccccttctga ataagtctta tcatcaagac ttccaaatac tctaaaaaac tcatctgttt
     1141 cgcttaattt tttattgtaa aatcccctat attctttcat ttctctagta ttcatcttct
     1201 acctcctatg tttttcttat aagaatatca caccgtactt atattttcaa tattaaatac
     1261 aaattttcat tttatgttca ttagcctaat ttatattatt ttttgaaatc tcaataagtt
     1321 atcatataag taagattttt tcagaactaa aatagaaatc ttagtaattt ctttattatc
     1381 tatctcagtt ctgaaatata ttattcttat ccaaacatta ttatagtgat taattatatt
     1441 agttattttt acctgaaatt ttatacatca aataagaata tataaatggt agtattacaa
     1501 ttacaaagat tacaaagata ttataaaaag gaatattaat aaatgcatta ataattaata
     1561 atattccacc aataagccaa atccatccag ctaaatggtg tgtcttattc caattatctt
     1621 catcattaag agtccatggt aaaattattc ctactgagta atttcgttta catttaggaa
     1681 gatagtttcc aaataaaata actattattc ctaaaattaa tcctgtataa aaattagact
     1741 ccaaactaac tcctgttgaa tataaaacca tcattatttg tataattact gaaagtatag
     1801 caactcccca ttttgataaa ttttgtataa catttgaaaa attagctttc ttaggctcat
     1861 tctcaagtct aaaccatgta tacaaatgga tacatagcat taacaatggt acaccaaaag
     1921 ctgctataac ctttggagca taattatctg gatttccata attatcaaaa tgaattgcaa
     1981 cttcatttgg taatctatta taaaaatata ttgatacaat aaatggtata aaacatatta
     2041 aagtagataa aataaattgt ttatttatcg cttttttcat tatctttttc tcccttctcc
     2101 ataaattgtg aaaaccaaag catgacctct tcgaaaactg aaatatttat ttcgtagaaa
     2161 ataaagttct tatactttgt ttcaaatatg agtcctgcct tttttagttg agatagatga
     2221 taagaaattg tagcattcgt catattaaat ttttcactaa tttctcctgc tgacatttta
     2281 ttctccctca acataaccaa tatttctctt cttatagggt ctgaaagagc tttgaatgtt
     2341 tctggaaacc ccaacaccat cacctcgcta tttagaattt catctaaata gaatataaca
     2401 taacatccat tttatttcaa tagctattta gaaatttttc taaatagtta tttctaaata
     2461 tttattgaaa atttttatat taagattctc aatttactta agtcgctttt atttaatctt
     2521 actttatcta atttttttaa cttaacaaaa gtgtattgca ccataattgt taaagcaaaa
     2581 acctaatgat tgaggtactt atatatataa caatactttt aattttaaat taaaagtagc
     2641 taaacccaat ttaaaaagta gttaagtcct atttaaatag aaaagaatga aacgagaaat
     2701 atactgtata aaagtacata aaaacatcta ctaattagat acaactataa cagaatatat
     2761 ttattattat aataacaaaa gaataaaaaa aattaattta gcataacctt gttaaatata
     2821 gatttgaata tgaatttaaa gttatgtaaa attaaaaata caggaatgaa aattccattc
     2881 ctgtataaaa tctaactttt gagtctcagt acaatcttat tttgagacaa tcttttttgt
     2941 tttatatttt cttatattta aaatataacg catatcttat gcaacatatt catatttttc
     3001 tttatattct ttcatcgcat cattccaagc gtcttgtact gttacacctc ttttattagc
     3061 aattttttgt gccagttcaa ttatcttcat agctcttctt gatatgttca taaacattcc
     3121 tcctacaaat taccatatat ttcatatata taaatcaagg ttatattttt atgatatata
     3181 atccttctat tgtaagatta cagtttatat gtgtattata tatgaactat attagaagat
     3241 aattagaatt tttataaagc tatatgatta gattaaatat aaaagcttta caattactta
     3301 taaatttaaa aagtctataa gctaaactaa tgtttgatat accaatttta cgaccataaa
     3361 taatgccatt actaaaaata ttggttttat catctttgaa cctttcttta tagcaacttt
     3421 agcacctaca taagctccca ttatcatcac taatgcaaac actatagcaa ttttataatc
     3481 tacttgacca tttatcatga ataataacaa tgaagttata ttacttgtta agtttaatat
     3541 ttttgtattt gcagaagcat gtaaaaaatc atatccatat atttttataa atccaaaagt
     3601 caaaaaagtt cctgtacctg gaccaaaaaa accatcataa aaacccatta taagagccat
     3661 aagcatccct aatcttaaat ttttcttatt aacagcttca aaattatctt cttgacctaa
     3721 atttttagaa ataaaggtgt aaatagccac tattaaaatc ataaccacaa ccaaaacatt
     3781 taatatctct tcacttattg ataatacaca tctcacacct agaacactac caataatagt
     3841 aaatggtact aattttttta aaaggttgtt attaattttt ccagactttg catatctata
     3901 ggcactactt atacatcctg ctgatgctgc aaatttattt gtaccaatgg caagatgtac
     3961 tggcactcca attgccataa gaacaggcat gcttataagt cctcctcctc ctgctataga
     4021 atctacaaaa gcagctaaaa acccccctat acataaaaaa ataactgaaa acataaaatt
     4081 cctccatcat tctctttcaa tttttcttac aatatatatt atataatctt atttaatact
     4141 tattatccag catattcttt ctatattcat ttggagttat actattaaac ttcttaaata
     4201 tttgtgaaaa ataactactg ttattaaaac ctactttctt acaaatatca ctaatactca
     4261 tgcttctatc taacagatat tttttagatt cttctatcct aagaagattt atatactcag
     4321 ttattgaaac tttatttctt tcattaaaaa tagaactcaa ataatttgga cttataaaaa
     4381 aaacatctga tatactattc aaatttatat tttctttata atattttttt atatattcgt
     4441 ttatattttc aattagattt cctttatctt ttctccaaaa tgctctattc ttatcaatac
     4501 actctttgga aaattcaaat aatacattcc ataaatcttc atcactgttt acaagtgata
     4561 tttttttatt atatttattt cttaaataag atataagttt taaatcctct aaatctctaa
     4621 gcactgttct agacaataca aatatcattt cctgaatagt atctctaaca tcattatatc
     4681 ttaatttgtt tgtatctatt agattataaa caccttctaa attcatattt ttaatttctt
     4741 tttcaatata aagttctaat tcaaagggat attcttttga agaattattg aacatatcta
     4801 tcggattaat aatatactct tcttctaata atctactatt tgctttttta agtgcctctt
     4861 caagtcttat attttctttt ctactcttca atatctcctc atcttttata ctaagttgat
     4921 tttcaaaaaa attcctctta gctatttcct gaataaattc agacatcatt aataaatttt
     4981 cttttaatac atataatcta cttttaggat ttaatggaaa ttcattgtaa attttgttta
     5041 tgtattttat atcaatacca gaactacttg ataattcaga taaattttta tctatatcaa
     5101 tagacttata tactataaaa ttaccacatt ctatatatcc aactatattt tcttctaata
     5161 ctataggtat ctctaaactg gaaacaccat actcacaatg gtacactttt tcaaagttat
     5221 cattatttat gcttttaaca agttttttag tacactgttt tatattttta caaatatcgc
     5281 aaaatttatt ttctttctta gtctcaaata tttctttata ctttaagtca tatacagata
     5341 ttctaagctt caatatatta gatatttgat ttgcaagatt ttcaattatg tttacattaa
     5401 ctaactcctg tatattgttt tcagaaaata ctataggtat ttgtctcaaa ctcgaaaatt
     5461 tatgaggaac ataagtaatt aatattacta aatcaatttt accagtgttt ataatttcat
     5521 gttctgaata tggtgggcaa taaactatag atgtttcctt tatattgacc tttttaccat
     5581 caattatttg tattccttct ccctgaatca catataaaag ctgttcttca cttaaatgaa
     5641 aatgcttttc ttggtagttt cccggaaaaa atcttacaat tccagcacta agtctattga
     5701 attgtgtttt tgatggttcg tgtatccaca taacctctcc ccaatcaaat ttttgtactt
     5761 cattatttga ctcactaaaa tactccataa gctcacctct tagtttttgt ctaaatattt
     5821 tttcttccct tcttatatta aaataatatc atcatcatta actttcatta ctataaaatc
     5881 atcatactct tttaatactc ctgtaatttt agttgcactt agtttactac aattcagttt
     5941 tttaatatat tgataaattc tataattact tttttatttt gtaaaatcag tgttttccca
     6001 aaataattat atctataaat gaaagtattt ttactgctta catcaatata tgttatcata
     6061 attttccttt ttattgcata tataaataac tgtatataac attgtccaat actatataga
     6121 aatacatcta agaaagaata ttattaaatt gttccaatta gtattatttt tcttatagaa
     6181 ataaaaaaac tgttggagtc ttttagaaaa attatttttt acataccttt tttgcttaga
     6241 tagtctatct tcacagctat tttgtatata cactcttcta gttcatgatt ttattttaat
     6301 atcttgctta tattgctgaa ataattgaat tcttttatct atcatattgt ctcttatatc
     6361 acaaacatat tgtttcttat atcacaaaaa tgaaagcatt cttatatctt caatatataa
     6421 acctgctttt tttaatcttg taataaatat aggatactct atattctctt cctagaaata
     6481 actaatacca cttatttttc tattatatag aaagtaataa atctttttct taataaaatt
     6541 caatagtaag tggaataaaa ttttatatga ataagaacat tataaaaata ctttatacaa
     6601 tagtcaataa aagatattag cttcaaatta tgttaaagtt gtattattta aagtgaaaaa
     6661 acaaataaaa aagaaataat agtataagta gaaaaatata cttaaaacaa ggcgaagcct
     6721 ctcttgtatc taaatcaagt agagaattaa atctaaaaaa gaaaataaat ataaaagatg
     6781 actcctgtac attacaagaa tcatcttatg gtttcataat cactccatgg tttttaactg
     6841 tctgatataa aggtctcagt tcactcatag catgaccacc ttttccgatt gctgaccccg
     6901 tcacttatgg acaaaatgtc cataagtgat agtcctctct taaaaccctc taaatagata
     6961 tatctcaagc accgcattga aaccagttgc tggaaacaaa ctgaagcgtt ctggaatagt
     7021 aaaagaaatt gccaccatat ccacgttact gtcctagttg ttactttgct aacttcggag
     7081 cgatttcctc taacaatacg cagtcaaatt ctgccttttt gctaagaaat ggcagatggt
     7141 ctgcatctgg tataaaaaaa atctgtttgt ctggcgccac tatttcatca aaaaatttct
     7201 tcgctggaag ataggggcta ttatagtcat tttctcccat gatgtagtat acagggacct
     7261 gatagtcaac tccataattt cttatgtcag cttcttccac taaaaaccgc aatacatcac
     7321 cttgattgtc aatcgcattt ggattgaaaa tggccgtatt ttttaactct ctcaatgaat
     7381 aatacggggt tgccagtata ctgattatat tgcccaaatc catatttata gaaagcccat
     7441 acttgctttg gtatgttctt actgtcataa gagctgccaa atagcttgga ccatattttg
     7501 ctggcggata tggtgcaata gcttccagcg ccttgatatc tttttgcttc cctgcagctt
     7561 tcaccatttc aagtgtcttt tcatagccca cgcgctcatt gtccaccata ttaacggtct
     7621 gcgcaatccc aatgtacgcg ctgtaatcct ccggataggt ttgcacagcc atagttccca
     7681 gaactgttcc ccagctatga cctataagga taattttctc cttgttgaac tcttgcttca
     7741 aatatgctgt cacctcatgg acgtcttgca gaacacgctc cgcgctcatg gtctgcaaaa
     7801 ctgctgccgg atcgttcgca aagtatgttt tgcctacgtt tcgctgatcc cagttcacca
     7861 cagtaaaatc attttcccac tcatactggt acagatgtaa aaatggcatc attgaattac
     7921 caggaccccc atgaacccaa aggatgatgg ggttgtctgc gttttgtccc cggatatata
     7981 acgcctgctg tatgccgccg atctccacca tttccatgcg gtcgattcca ggagcttcta
     8041 ttttatggct tgtacgtata atcgtggggg ctatcagacg caaaccggca aacgccagaa
     8101 caaaaacagc aactagtatg caaagtgtga ttaatatcat tttaagtacc ttctttcatg
     8161 aattttttta gccatagata tctcctctaa cattaaaaaa aatatgttgc tattttagtt
     8221 ttgttactct acctgtccca ttggtttcct ttcataaaaa atattaattg attctataat
     8281 ctcatcttcc aggatatcaa ctcctatttg tctcataaga aactgtaaga attgaaaccg
     8341 tttacgaagt gtaggaaagt ccccctgaaa tacatctgta tcacaccaaa agttaaagag
     8401 cagcaaaatt acctctgcgc attcatctgg gaactctgtg atgatgcttc tatcctctat
     8461 gccttctcgt aaaacatttg ctaatattgg tgctagtttt ttcaaattat cctgtgtaaa
     8521 tgccagtatg atatgcggac tttctatcgc gcttgtaatc atgttactag attcttttat
     8581 cacctcatcc gttaaatgcc gcctaactaa acttctaagc ttctcttttg ctgtaagtcc
     8641 atgcatttca ccgagccatt gatttactgt ctctattatc tgttcaaagc gcctttccat
     8701 gaccacatta aaaatatctt cttttgaact gaagtgatga aaaattccgc cctttgacat
     8761 tcctgaagca tcaacaatat tttgcatact tgttttgtca tatccttttt cagcaaacaa
     8821 ctttgcagaa atggtaatga tattttcaat agcttgcttt ggattgttct ttctagtcat
     8881 tatataactc cttcttatta aaaaccgact gttggttttt attatataag ctattcctgc
     8941 ttctgtcaag taacattgtg tttatggcaa aacaataagg tttggtggtt agacaggtat
     9001 taattagact aatgcgactt tcccctagat ggaacccttg gtaaatttgc aatctttacc
     9061 ggctttgatt atatctgtaa gcaaggcagg tatggccaca cctgccctgt ttgcccctcg
     9121 gatattcatt cctatccctc ctctccttag ccattacacc aaaacgccgc tcattgtctc
     9181 caatggcggc gttttaaaga tatgatttct catgctgctg aaatatgcaa aaaatataag
     9241 atgcccttta ttatttttcc tacaatagaa aagaaaagta ttgaagaatg ggttaatatt
     9301 ggagcaaata tgctttgttt ggcacaagat actaccttta tcacttatgt tatcaatcaa
     9361 ttattatctt tttataatga gattgtacca attcaaaaac aacattaaat tataaatcta
     9421 attttatatt aaaagagact aatattttat ctatctctat taaggatatt ttcttatgta
     9481 tcataatatt agtctctctt attattatat actgctatca tcattagttg ctatttatac
     9541 tatttttata atatacaaat ttattcagct aacgttttgc ctaattctat acactcatct
     9601 tttgcttctt catttgggtc ttccattgct gtaattcctt ctccaccaat aattgtagca
     9661 ccagcatttt gcatacgttc ttcccagtct ctcatccatt cacaatttcc ccatccatat
     9721 gaaccaaata atccaatctg tttacctgat accatagatt ctaattctga aacaaatggc
     9781 tccatatacc cctcttctag ttgctctgct cccatagatg ggcaacctaa tgcaaattta
     9841 tcttcttctt ttaaatcact tggtttcagt aagctcacat ctaaaacttc tggtgtctta
     9901 ccttttaact tcacaccttc agccacaaaa tttgccattt tttcagtatt tcctgttcca
     9961 ctccaataaa caatatatat tttactcatt tttacctcct gtagtatttt ttaattaatc
    10021 aatagttagt tatagctaac taacatctaa aaaacaaaag atttctttat ctgaaatctc
    10081 tttatttttc taaatataga atatcatggt tgattttgaa attcaatact tattgataat
    10141 atttatcatt tatattttat attcatttta taatatcaaa acactgtatc gtatttctaa
    10201 tctttcatag aaaaatttct aacttatagt acttttgcat ctcttataaa tcttttatat
    10261 gtataagtac atagaaaaac acaccttttc cagatgtgct atctataata tcgtatattt
    10321 atttttcaat tctaactagc taatatgttt ataaatttta tcacttaata cctttataca
    10381 ttgatgtaaa atcttacacc taagtaattt ttattatttg tctcgactct atataatata
    10441 gctattttat catcaaatca aaaattatct tttgctatta ttcttgtatt tataaagatt
    10501 taaatataag tatccatttc cttgttccgt tctaggtatt ccaagcgctc tcgtacattt
    10561 tattaattgt gcatacagtt cagcttcatc taaatctctt tcaaactcct ctcttgccca
    10621 ttctttaatt agtgctaatg agcctgatac gtatggtgca ctcatactgg taccactcat
    10681 aatagcaagt ttattatcca tataagtcga tataatattt cttcctggag ctaccaaatc
    10741 tattgtagta tttgaattac taaacttttc aaccaaatag ttctcattta ttgcacctac
    10801 ttctattacc tcagcataac tggctggata actatactca cttgtactag aatcaccatc
    10861 tccattatta cctgctgcac acactacaga aatattattt tttactgctt gcatgacagc
    10921 attttttaaa ttcttatcat ctttgtttcc cccaagagac atagatataa tatcaacctt
    10981 gttatttaca gcaaagttaa tagcattaat tatactttga tatgttccag taccatcttt
    11041 atttaatgct tttgctatta ataatttaca atctggagct actcccataa cttcattatt
    11101 ataattagat gcagctataa tacccgccac atgagttcca tgaccattaa aatcctcata
    11161 tatattttta tttccattac tgtcatcact aaaatttgca ccaccaatta tttttccttt
    11221 taaaagagga tgagatatat cacaacctgt atctattata ccaactacaa tatttttacc
    11281 agtataacct tcatcccaca ttcccctagc attcatttgt tttattccat atgggaattt
    11341 attttttgca cctcttagat tttcatttat ttcatatgga attagtttca ttcttttatt
    11401 catcatatat cctcctaaaa attttattgc ttataaaaat catgaatttt attttataat
    11461 agg
//
LOCUS       DAYAOO010000112        11374 bp    DNA     linear   BCT 12-OCT-2024
DEFINITION  TPA_asm: Clostridioides difficile isolate ST8-SSI-h139-18
            SAMN40601845-rid21577343.denovo.114, whole genome shotgun sequence.
ACCESSION   DAYAOO010000112 DAYAOO010000000
VERSION     DAYAOO010000112.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN40601845
            Sequence Read Archive: SRR28438827
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 11374)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11374)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-MAY-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-MAY-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002157583.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002157583.1
            Genome Coverage       :: 163x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/11/2024 16:19:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 4,038
            CDSs (total)                      :: 3,963
            Genes (coding)                    :: 3,930
            CDSs (with protein)               :: 3,930
            Genes (RNA)                       :: 75
            rRNAs                             :: 6, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 60
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 33
            CDSs (without protein)            :: 33
            Pseudo Genes (ambiguous residues) :: 0 of 33
            Pseudo Genes (frameshifted)       :: 7 of 33
            Pseudo Genes (incomplete)         :: 25 of 33
            Pseudo Genes (internal stop)      :: 11 of 33
            Pseudo Genes (multiple problems)  :: 8 of 33
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11374
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN40601845-rid21577343.denovo.114"
                     /isolate="ST8-SSI-h139-18"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Denmark"
                     /collection_date="2018"
                     /collected_by="Statens Serum Institute"
     gene            complement(67..633)
                     /locus_tag="ACGI5H_003438"
     CDS             complement(67..633)
                     /locus_tag="ACGI5H_003438"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898142.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CD3073 family putative ECF transporter S
                     component"
                     /protein_id="HFG9699126.1"
                     /translation="MDTKKVTFSSMCIVINIVLGMVISMINIPLLFLDTVGTVLGAVV
                     LGPFWGALIGGCTNLVLGVISGPTNIPFALVNIVLGLIVGYISKKKGFGYKEAIITGV
                     ILSIVCPLIGTPISVLLFGGLSGSGADLLVGFLVQSGQKIFTAAFFPRILSNIVDKPL
                     SCIMVVYFISKMPKGFIKQYSKNTSSSY"
     gene            799..1320
                     /locus_tag="ACGI5H_003439"
     CDS             799..1320
                     /locus_tag="ACGI5H_003439"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861802.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CD3072 family TudS-related putative desulfidase"
                     /protein_id="HFG9699127.1"
                     /translation="MKRNREIVVVCHCILNCNSKVEGLSEFKGAQNIAINLINKGYGI
                     IQLPCPEMIMYGINRWGHVKEQFDNLFFREQCRQMLIPHVRQFDEYLKNDYDIKSIIA
                     IDGSPSCGYNKTCSSKRWFGELSGCNELMDKIKDIQMVDGKGIFIEELEKLLKEYNLE
                     IPIVGFDELREDK"
     gene            2119..4197
                     /locus_tag="ACGI5H_003440"
     CDS             2119..4197
                     /locus_tag="ACGI5H_003440"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422496.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyl hydrolase"
                     /protein_id="HFG9699128.1"
                     /translation="MIKISEDYIEKRFDNELLRIEAWGKNSLRIRSFVDQNFVDENYA
                     LNEKPKLNKDDITINKNEDGSAIIKNGKIKAVLDHRDRITFYNDKNEILLKEYIRLRA
                     VKHDDGGEDVGTIEITKDFNSTLKLKSREYRPSYSGEFEVTTRFESEPSEKIFGMGQY
                     QHKFLDLKNTVLELAQRNSQISVPFYISSLGYGLLWNNPGIGKVSFAKNMTEWKMFST
                     NFIDYWITCGESPKELNKNYSQVTGTVPMMPENLLGLWQSKLRYRTSEEVLDVVKEYS
                     KRGIKLSSIAIDYFHWPKQGEYKFDLDYWKNPKELVKKLKEEYSVEPIVSVWPTVQSD
                     AENYNDYLENGYLVNVNRGVRMTMQIQGNTVFVDMTNENAREYVWDRIDKNYKQLGID
                     YYWLDVAEPGYSVYDFDNYRYKKGNVLSCGNIYPIDYLKMIYDGLHNDIESVVTLVRG
                     AWAGAQKYGALVWSGDIDSSFEAFNNQVNTGLNMGLAGIPWWTTDIGGFHGGNPKDPE
                     FRELMVRWFQYATFSPILRMHGDRLPHSKPLSNKGGGSMVTGAPNEIWSYGEEVEVIL
                     TKFIKIRESLKTYLKKLMKEAHEDGTPVMRTLFYEFPEDDKTWEVDNTYMLGDEILVA
                     PIMNYKDRSRKVYLPKGHTWENIFSGVSYEGGKTYEVECPLEEIPIFLKQDSSYNFKE
                     LKNILGEVKS"
     gene            4197..4976
                     /locus_tag="ACGI5H_003441"
     CDS             4197..4976
                     /locus_tag="ACGI5H_003441"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422498.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS
                     mannose/fructose/sorbose/N-acetylgalactosamine transporter
                     subunit IIC"
                     /protein_id="HFG9699129.1"
                     /translation="MEPQLWQLLLIVLYGFFINYEKNSTMFGTYQPVTAGFITGLILG
                     DINTGLYIGGTLQLLSLGISNFGGASIPDYQTASIVATFITITTKQEASVGISIGIPV
                     ALLMVQLDVLRNTIGIWLVHKAEDGAKKGNYKNITYMQMLGVLLTAATTGIPVALSVI
                     FGPSLINTILKYTPEWLTGGLTVAGGLLPAVGIGLLLRYLPAKEYFSYLVIGFVLAVY
                     MKVPLLGVALIGGAIALIIYKKNLENQEQQYTVVGGMDEDE"
     gene            4969..5778
                     /locus_tag="ACGI5H_003442"
     CDS             4969..5778
                     /locus_tag="ACGI5H_003442"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427216.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:1902495 - transmembrane transporter
                     complex [Evidence IEA];
                     GO_function: GO:0016301 - kinase activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA];
                     GO_process: GO:0016310 - phosphorylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system mannose/fructose/sorbose family
                     transporter subunit IID"
                     /protein_id="HFG9699130.1"
                     /translation="MSDKVSLNKSNEKVKKSVLWRWFFTSSVSSNYEKMQALAYCYAV
                     LPFLKVVYKDNPEKLQSAVLNHLQFFNTNPWVAPYILGINVAMEELSSEETEEAVASI
                     KTGLMGPVAGLGDSLFVVIPWTIFGAIAANMAIDGSPFGILLWIVVSVALKLLSIPLF
                     NAGYTSGTKLISSIEKSLKILTESTSILGLMVVGALIPSVVKANVALNFQQGDFTMKG
                     QEILDQIMPGLVPAILVVIVYWALKKNIKPIYLILGVMVVSIILYALGILK"
     gene            5798..6280
                     /locus_tag="ACGI5H_003443"
     CDS             5798..6280
                     /locus_tag="ACGI5H_003443"
                     /EC_number="2.7.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009906215.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HFG9699131.1"
                     /translation="MEMKGIKNIRIDDRLIHGQVATMWSNKLGVTRLMVVNDAVANNS
                     VQKQVLRMATPAGIASSIITEETAIKNITAGKYEGQNVLLIVKSPVDLIPFVEAGFKI
                     HNINVGNMSSRKDTTVLRPNISVTEEEKEAFKRLLDEGIEITTIMTPDDKKTYLVDIL
                     "
     gene            6301..6705
                     /locus_tag="ACGI5H_003444"
     CDS             6301..6705
                     /locus_tag="ACGI5H_003444"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422503.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:1902495 - transmembrane transporter
                     complex [Evidence IEA];
                     GO_function: GO:0016301 - kinase activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA];
                     GO_process: GO:0016310 - phosphorylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HFG9699132.1"
                     /translation="MNSIILMSHGNMAEEVLNSAKMIIGDSIDYPTVNMKQDDGIEGT
                     IEKLKKALEVYKESSEIIIMADLLGGTPCNAALLVANNDSRIKIISGLNLGMVIESAF
                     LDTKELAAKLEKIGKDNISMVEQNANLLSDDE"
     gene            complement(6861..8021)
                     /locus_tag="ACGI5H_003445"
     CDS             complement(6861..8021)
                     /locus_tag="ACGI5H_003445"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903434.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="HFG9699133.1"
                     /translation="MVTDKYTIREMNERLVLEQIIKNGPISRASIASTIGLNKATISA
                     ITKKLIDESLVHEIGIGNSTHSGGRKPILLVFNKCAGISLSMDIGYDYIFSSLSYLDG
                     TIINSKKLTDIQVSKDNVIQLIDEIINSYNISKIDTPYKVIGLTLAIHGITCENKVLF
                     TPYYNLNEIDLYSILSKKYDFPIHIENEANLTALAENTFSTVHNSLLSLSIHSGFGSG
                     IIINNKLYSGRNGMSGEIGHTIIMPNGKLCPCGNRGCLEQYCSEKKVFEQLSSLENIP
                     KIDSDIVKQLYYEDNHNAKKVIHEFCSYLTIAINNAITTYAPEIIYLNSQIISDIPEI
                     LQITKDMLVSSFNKGINIEISSLGSEASLYGGSAVNIKSFLNIQNLTLINEI"
     gene            8229..9779
                     /gene="xylB"
                     /locus_tag="ACGI5H_003446"
     CDS             8229..9779
                     /gene="xylB"
                     /locus_tag="ACGI5H_003446"
                     /EC_number="2.7.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012816371.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004856 - D-xylulokinase activity
                     [Evidence IEA];
                     GO_process: GO:0005997 - xylulose metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="xylulokinase"
                     /protein_id="HFG9699134.1"
                     /translation="MKLEYVLGVDIGTSGTKTVLFDKLGNTIKSCTYEYPLIQEKSGW
                     AEQDANDWWKAVVESIREVVQSSNISSECIKGIGLSGQMHGLVMLDNEGKTLRNSIIW
                     CDQRTVKECEEITDLVGEERLIEITANPALTGFTASKILWVRNNEPDIYKNTNKILLP
                     KDYIRYKLTGEYATEVSDASGMQLLDIRKRDWSDEVLEKLNIDKNLLGKVYESQEITG
                     YVTRDVSSLTGLKEGTIVVGGAGDQAAGAIGNGIVKDGVVSSTIGTSGVVFAYTKEPK
                     IDKEGRVHTFCHAIPNTWHVMGVTQGAGLSLKWFKDNFCQSEVEVSNSLGEDVYEIIN
                     NQVSKVPTGCNGLLYLPYMMGERTPHLDPYARGVFFGLSPIHSKKEIARSIMEGVSYS
                     LKDCMDIIENLNIDVNEVRASGGGGKSKVWRQMQADMFNQDVYTINSSEGPALGVAIL
                     ALVGAGIYENIQKACDAIIKTSTKLEPISENVDTYNIYHRLYKRIYKSLKDDFKLLDE
                     VVNAKINN"
     gene            9875..11212
                     /gene="xylA"
                     /locus_tag="ACGI5H_003447"
     CDS             9875..11212
                     /gene="xylA"
                     /locus_tag="ACGI5H_003447"
                     /EC_number="5.3.1.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891378.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0009045 - xylose isomerase activity
                     [Evidence IEA];
                     GO_process: GO:0042732 - D-xylose metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="xylose isomerase"
                     /protein_id="HFG9699135.1"
                     /translation="MSEIFKGIGQIKFEGVKSDNELAFRYYNPEQVVGNKTMKEHLRF
                     AMSYWHTLCGEGNDPFGVGTVERPWNNITDPIEIAKIKVDAGFEFMSKMGIEYFCFHD
                     RDIAPEGRDLEETNKILDEIVEYIKVNMEKTGIKLLWGTANMFGNPRFVHGASTTCNA
                     DVYAYAAAQVKKAMEITKYLGGENFVFWGGREGYETLLNTNTELEMDNFARFLQMAVD
                     YAKEIGFTGQFLIEPKPKEPTKHQYDFDTATVLGFLRKYNLDKYFKMNIEANHATLAG
                     HTFQHELNIARINNVLGSIDANQGDLLLGWDTDQFPTNIYDATLAMYEVLKQGGIAPG
                     GFNFDSKVRRASFEVEDLFLAYIAGMDTFAKGLLIAHKLLEDEVFENFTKERYASFSE
                     GIGKDIVEGKVGFKELESYALQMPVIKNKSGRQEMLEAILNRYIYEVDTISNK"
BASE COUNT         4382 a         1308 c         2054 g         3630 t
ORIGIN      
        1 aatgttatat aaaaatgagt atatagcatt ttaaagagta ataaacctta cataataaat
       61 gatttattaa tatgaactag aagtattttt actatattgt tttataaaac ctttaggcat
      121 tttacttata aaatatacca ccataataca agacaaaggt ttgtctacta tattactaag
      181 aatccttgga aagaacgcag cagtaaatat cttctgacca gactgaacta aaaaaccaac
      241 caataaatca gcaccacttc cacttaaacc accaaacaat aaaactgaaa taggagtacc
      301 aattaaagga caaacaatag ataaaattac tcctgtaata atagcttctt tataaccaaa
      361 accttttttc ttagaaatat atccaacaat aagaccaagg acaatattta caagggcaaa
      421 aggtatattt gtaggacctg atataacacc taaaactaag tttgtacatc caccaataag
      481 agcaccccaa aaaggaccta atacgacagc cccaagtaca gtaccaactg tatctaaaaa
      541 taataatggt atatttatca tagatataac catacctaag acaatattaa taactatgca
      601 cattgaagaa aatgtgactt ttttagtatc caattataat acctcctaaa aaaatatata
      661 catttatcat agtatagatt ataaaagatt actaattgta tatttctata tagaatattg
      721 gaaatataga acaaataaat aatataatta tcaaaatatg tagtatcatt aaaattaaga
      781 ataactaagg agattattat gaaaagaaat agagagattg tagtagtatg tcattgtata
      841 ttaaattgta attctaaagt ggagggattg tcagaattta agggagcaca aaatatagcg
      901 ataaatttaa taaataaagg gtatggaata attcaactac catgcccaga aatgattatg
      961 tatggaataa ataggtgggg acatgtaaaa gaacagtttg acaatttgtt ttttagagaa
     1021 caatgtaggc aaatgttaat acctcatgta aggcagtttg atgaatattt aaaaaatgat
     1081 tatgatataa aaagtatcat tgcaatagat ggcagtccaa gttgtggtta taataagaca
     1141 tgtagttcta aacgttggtt tggtgagtta agtggttgca atgaattgat ggataaaata
     1201 aaggatatac aaatggtgga tgggaaaggt atttttatag aagagctaga aaagctactt
     1261 aaagaatata atttagagat acctatagtt ggatttgacg agcttagaga agataagtag
     1321 agatataaat atttattgtc tcattatgaa acaccattat atttggcaga aaaatatgac
     1381 tgatggacag tacaggaacc atttttaagt ggagtaatta gtacttataa agatgtatcc
     1441 actagctgaa agaaaatgta gaaaggtaat aaatgaatta agaagtagat aatatatata
     1501 aaggagtgtc taaaagtgaa ctttttagtt tatgagacac tcttttttta tattaaatca
     1561 agtatattaa atcaaatata ttttaatcat tttagcaatg aaaaataaat ttatctatat
     1621 tttgagacaa catctttttt agttttattt atttgttgtc gtttttgact tggtatacaa
     1681 ttgtatattt tcttaaataa tttcataaat tatttataat tataaaatcc attgttttga
     1741 acaatatcta atatattatt atctgtattt ataaggtcac tatacatatt ttcaagtccg
     1801 atattatcta cataataggc aaatgttatt cctgtatgtg ttttaaaaaa actagatgta
     1861 tataggtatc atcacagata ttaaaagtat aaataaaaga tattaagaac aactttccag
     1921 caatatatta gaaaatttta ctaaaatccg gaaagcgatt gacaaacaaa gtcaaataaa
     1981 gtatattatt ggtaagttag tttaatgtac aaatgaatta tatataaaac ctaatttata
     2041 aataacgata ctaaacgaca ttatttaact taagttacac aaagatagaa tattatacca
     2101 ttgatttagg aggtagccgt gataaaaata tctgaagact atattgaaaa aagatttgac
     2161 aatgaactat tgcgaataga agcatgggga aaaaactctt tacgtattag gtcgtttgta
     2221 gaccaaaatt ttgttgatga aaactatgct cttaacgaaa aacctaagtt aaataaagat
     2281 gatattacaa ttaataaaaa tgaagatgga agtgcaatca ttaaaaatgg aaagataaaa
     2341 gctgtcttag accatagaga tagaattact ttttataatg ataaaaatga aatattattg
     2401 aaagaatata ttcgattaag agctgtaaaa catgatgatg gtggagaaga tgtagggaca
     2461 attgagatta ccaaagactt taactctact ctaaagttaa aatcaagaga atatcgacca
     2521 agctatagtg gagaatttga agtaactact agatttgaat ctgagccttc tgaaaagatt
     2581 tttggaatgg gacaatatca acataaattt ttagatttaa agaatactgt tttggagtta
     2641 gcccaaagaa attctcaaat atcagttcct ttttatattt ctagtctagg ttatggactt
     2701 ttatggaata atccgggaat tggaaaagta tcttttgcta aaaatatgac agaatggaag
     2761 atgttttcta caaattttat agattattgg attacttgtg gagaaagccc aaaagagtta
     2821 aataaaaatt actctcaagt tactggaact gttcctatga tgcctgaaaa ccttttagga
     2881 ctatggcaaa gtaaactaag atatagaact tcagaagaag ttttagatgt tgtgaaggaa
     2941 tattctaaaa gaggaattaa gctttcatca attgcaattg actattttca ttggcctaag
     3001 caaggtgaat ataaatttga cttagattat tggaaaaatc ctaaagaatt agttaaaaaa
     3061 ttgaaagaag agtattcagt agaaccaata gtatctgtat ggcctacagt tcaaagtgat
     3121 gcagaaaact acaatgatta tttagaaaat ggctatttag tcaatgttaa tcgtggtgtt
     3181 agaatgacaa tgcaaattca aggaaataca gtctttgtag atatgacaaa tgaaaatgca
     3241 agagaatatg tttgggatag aatagataaa aattataaac aacttgggat tgactattat
     3301 tggttagatg tagctgaacc tggctattct gtgtatgatt ttgataacta tagatataaa
     3361 aaaggaaatg ttttaagttg tggtaatatt tatcctattg attatttaaa aatgatttat
     3421 gatggtttac ataatgacat agagtctgtt gtaactcttg taagaggagc ttgggcagga
     3481 gctcaaaagt atggagcttt agtatggtct ggtgacattg attctagttt tgaagctttt
     3541 aataatcaag taaatacagg gttaaatatg ggactggcag gtataccatg gtggactact
     3601 gatattggag gtttccatgg aggaaatcct aaagacccag aatttagaga acttatggta
     3661 agatggttcc aatatgctac tttttcacca attttgagaa tgcatggaga tagattgcct
     3721 catagtaaac cattatcaaa taaaggtgga ggctcaatgg taactggagc tcctaatgaa
     3781 atatggtctt atggtgaaga agttgaagta attcttacaa aattcataaa aattagagag
     3841 agcttaaaaa cttatttaaa aaaactgatg aaagaagcgc atgaagatgg aacaccagtt
     3901 atgagaactt tattttatga atttcctgaa gatgataaaa cttgggaggt ggataataca
     3961 tatatgcttg gagatgaaat tttagtagct ccaataatga attataaaga tagaagtaga
     4021 aaagtatatt taccaaaagg acatacatgg gaaaatatat ttagtggagt tagttatgaa
     4081 ggtgggaaaa cttatgaagt tgaatgccca ctggaagaaa ttcctatttt cctaaagcaa
     4141 gattccagtt ataattttaa agaactaaaa aatattttgg gagaggtgaa atcataatgg
     4201 agccacaatt atggcaatta ttattaatcg tactatatgg attttttata aactatgaaa
     4261 aaaattcaac aatgtttgga acatatcaac cagtaacagc aggttttatt actggtctta
     4321 tcttaggaga tataaataca gggttatata ttggaggtac attacagcta ttatcattag
     4381 gtattagtaa ctttggtgga gcatcaatac ctgattatca aacagcaagt atagtagcca
     4441 catttataac tattacgact aagcaagaag catctgtagg aatctctata ggtattccag
     4501 ttgctttatt gatggtacaa ttagatgttc ttagaaatac tattggtata tggctagttc
     4561 ataaagcaga agatggagct aaaaaaggaa attataaaaa tataacctat atgcaaatgt
     4621 taggagtact attaacagca gctacaacag gtattccagt tgctctatct gtaatatttg
     4681 gaccttcttt aattaatacc attttgaaat atacacctga atggttaaca ggtggtttaa
     4741 cagtagctgg aggactactt ccagcagtag ggataggatt attacttaga tatcttcctg
     4801 ctaaggagta ttttagttac ttagtaattg gttttgtttt agcagtatat atgaaagtac
     4861 cattattagg tgtagcttta attggtggag caattgcact tataatttac aaaaagaatt
     4921 tggaaaatca agaacaacaa tatactgtag taggaggtat ggacgaagat gagtgataag
     4981 gtatcattaa ataaatcaaa tgaaaaggtg aaaaaaagtg tcttatggcg ctggtttttt
     5041 actagttctg tttcttcaaa ttatgagaag atgcaggcct tggcatactg ttatgcagta
     5101 ctaccttttt taaaagtagt atacaaagat aatccagaaa agttacaaag tgctgtatta
     5161 aatcatttac aattttttaa cactaatcct tgggttgccc cttatatttt gggtattaat
     5221 gtagcaatgg aggagttatc aagtgaagag actgaagagg ctgttgcttc aattaaaaca
     5281 ggcttgatgg gaccagtagc aggtttagga gatagtttat ttgtcgttat tccgtggaca
     5341 atttttggag ctatagcagc taatatggcg atagatggaa gtccatttgg aatcttactg
     5401 tggattgtag tgagtgtagc attgaaatta ttaagtatac cactatttaa tgctggttat
     5461 acatcaggta ctaagctaat atcttcaatt gaaaaaagtt taaagatttt aactgagagt
     5521 acatctattt taggtttaat ggttgtaggt gcattaatac cttcagttgt aaaagctaat
     5581 gttgctttga actttcaaca aggtgatttt acaatgaaag gtcaagaaat attagatcaa
     5641 attatgcctg ggttagttcc tgcaatttta gttgtgattg tttattgggc tcttaaaaag
     5701 aatataaaac ctatatactt aattttagga gtaatggttg tttcaataat tttatatgca
     5761 ttaggtattt taaaataagg aaaggatgat attagatatg gaaatgaaag gtattaaaaa
     5821 tattcgtata gatgaccgtt taatccatgg tcaagttgca actatgtgga gtaataaatt
     5881 gggtgttaca agattaatgg tagtaaatga tgcagtagct aacaattctg ttcaaaaaca
     5941 agttttaaga atggctacac ctgcaggtat agcgtcatct ataattacag aagagactgc
     6001 tataaaaaat attactgcag gaaagtatga aggacaaaat gtattattaa ttgttaagtc
     6061 tcctgtggac cttattccat ttgtagaggc aggatttaaa atacataata taaatgtagg
     6121 aaatatgtca agtagaaaag atacaacagt tctaagacct aatatcagtg ttactgaaga
     6181 agagaaagaa gcatttaaaa gacttttaga tgaaggaatt gaaattacaa ctataatgac
     6241 gcctgatgat aagaaaactt atcttgtaga catcttatag atttaaagag gtgtattaaa
     6301 ttgaatagta ttattttgat gagtcatggc aatatggctg aagaagtctt aaattctgca
     6361 aaaatgataa taggggattc tatagattat cctactgtaa atatgaaaca agatgatgga
     6421 atagaaggaa caatagaaaa attaaaaaaa gctttagaag tgtacaagga aagttcagaa
     6481 ataattataa tggcagattt actaggtgga actccatgca atgctgcttt attagtagcc
     6541 aataatgaca gtcgaattaa aattatttca gggctaaatt taggtatggt tattgaatca
     6601 gcttttttag atacaaagga attggcagca aaattagaga aaataggtaa agataatatt
     6661 tctatggttg aacaaaatgc aaatttatta tctgatgatg agtaggaaga ttatattaat
     6721 atttaaaacg aaatacttat gttaatactt aattgatata caatttttaa aaaatatagc
     6781 taatcttgca taaactatat aataaatcta attttagaat gtataattta aagggttatg
     6841 gctgtatata gtcataaccc ttatatttca ttaattaaag ttaaattttg tatattcaaa
     6901 aagctcttga tatttacagc agagccacca tatagagatg cctcagaccc taatgatgaa
     6961 atttctatat ttattccttt gttaaaagag ctaactaaca tatcttttgt aatctgtaat
     7021 atctcaggga tatcactaat tatttggcta tttaaatata ttatttcagg agcataagtt
     7081 gtaatagcat tatttatagc tattgttaag taactacaaa actcatgaat aacttttttg
     7141 gcattatggt tatcttcata atatagttgc tttactatat cagaatctat tttaggaata
     7201 ttttctaaag aagaaagctg ttcaaatacc tttttttctg aacaatactg ttctaaacag
     7261 ccacgatttc cacaaggaca tagtttaccg ttaggcatga tgatagtgtg accaatttct
     7321 ccactcatac catttctgcc actatataat ttattattta ttataatgcc tgaaccaaat
     7381 ccactgtgaa tactgagact aagtagtgag ttatgtacag ttgaaaaagt attctcagct
     7441 aaagctgtta agtttgcttc attttctata tgaataggaa agtcatactt tttgctaagg
     7501 atgctatata agtcaatctc attaagattg taatatggag taaacaatac tttattttca
     7561 caagtaatcc catgtatagc caaagtaaga ccaattacct tataaggagt gtctattttg
     7621 gatatgttat aactatttat aatttcatct atcaattgta taacattgtc tttacttact
     7681 tgtatatctg ttaatttctt agaatttata atagttccat ctaagtaaga tagagaagaa
     7741 aatatatagt cgtatccaat gtccatactt aaagaaatcc ctgcacattt attaaatact
     7801 aataatatgg gttttcttcc gccactatga gtactatttc caattcctat ttcatgaact
     7861 agagattcat caataagttt tttggtaata gcggatatag ttgctttatt caatcctata
     7921 gtagaagcta tacttgccct agaaatagga ccatttttta taatttgttc aagtaccaat
     7981 ctttcattca tttctcgaat agtgtattta tcagtaacca atttgatatt cctccttaaa
     8041 ataatattgt aatacttttt acacaaaaat aaaaggttat tttgcattga caaagataat
     8101 taaatatttt attattagtt cataagttag tttaatatac taacaaaaat aaagcaagta
     8161 aaatatacct aaaatataaa aaaattagga taggaaaacg atagttatga agtggcattc
     8221 aaggagggat gaagttggag tatgtattag gtgtggatat tggtacatca ggtacgaaaa
     8281 cagttttatt tgataaacta ggaaatacta taaaaagttg tacatatgaa tatcctctta
     8341 tacaagagaa atcaggttgg gcagagcagg atgcaaatga ttggtggaaa gctgtagtcg
     8401 aatctataag agaagtagtt caaagttcaa atataagcag tgaatgtata aaaggaattg
     8461 gattatcagg gcagatgcat ggtctagtta tgctggacaa tgaaggtaaa acattgagaa
     8521 actctataat atggtgtgac caacgaacag taaaagagtg tgaggagata actgatttag
     8581 taggtgaaga aagactgatt gaaataactg ctaatccagc acttacagga tttacagcat
     8641 caaagatatt atgggttaga aacaatgaac cagatatata taaaaatact aataaaatac
     8701 ttcttccaaa agattatata agatacaaat tgacaggtga atatgctaca gaggtatcag
     8761 atgcaagtgg tatgcagttg ctcgatataa gaaaaagaga ttggagcgat gaagtactag
     8821 aaaagttaaa tatagataaa aatcttttag gtaaagttta tgaatcacaa gagattacag
     8881 gttatgtgac tagagatgta tcaagtttga cagggcttaa agaaggaaca atagtggtag
     8941 gaggagctgg agaccaagca gcaggagcta taggaaatgg aatagttaaa gatggagtag
     9001 tttcatctac tataggtaca tcaggtgtag tatttgctta tacaaaagag ccaaaaattg
     9061 ataaagaagg tagagttcat actttctgtc atgcaatacc aaatacatgg catgttatgg
     9121 gagttactca aggagctggc ttgtcattaa aatggtttaa agataatttc tgtcaaagtg
     9181 aagtggaagt ttcaaattct ttaggtgaag atgtatatga gattataaat aatcaagtaa
     9241 gtaaagtacc aacaggatgt aatggattgc tttacttacc atatatgatg ggagaaagaa
     9301 ctcctcatct tgacccttat gcaagaggtg tgttctttgg attatctcca atccattcta
     9361 aaaaagaaat tgcaaggtca ataatggaag gtgtttcata tagtcttaaa gactgtatgg
     9421 atataataga gaatcttaat atagacgtta atgaagtaag agcctcaggt ggaggtggaa
     9481 aaagtaaagt atggagacag atgcaagcag atatgtttaa tcaagatgta tatactataa
     9541 attcaagtga aggaccagca cttggagttg caattcttgc attagtagga gctggaatat
     9601 atgaaaatat acaaaaagct tgtgatgcta taataaaaac ttcaactaaa ttagaaccaa
     9661 taagtgaaaa tgtagataca tacaatatat atcatagatt gtataaaaga atatacaaat
     9721 ctttgaaaga tgactttaag ttattagatg aagtagttaa tgcaaaaata aataattaaa
     9781 ttagcttaaa aagaaaaata aagatagaaa atagttttaa attaagaaaa catactacat
     9841 atattatatg tgtaaaatat taggaggaca tgaaatgagt gaaatattta aaggaatagg
     9901 acagataaaa tttgaaggag taaaatctga caatgaatta gcatttagat actacaatcc
     9961 tgaacaagtg gtaggtaata agactatgaa agaacactta agatttgcaa tgagctattg
    10021 gcatacttta tgtggagagg gtaatgaccc atttggagta ggcacagtag agagaccttg
    10081 gaataatata acagacccaa ttgagatagc aaagattaaa gttgatgcag gatttgaatt
    10141 tatgtctaag atgggaattg agtatttctg ttttcatgac agagatatag caccagaagg
    10201 aagagattta gaagagacaa ataagatatt agatgaaata gttgagtata taaaagttaa
    10261 tatggaaaag acaggtataa agttattatg gggaactgcc aatatgtttg gaaatccaag
    10321 atttgttcat ggtgcatcta caacatgtaa tgcagatgta tatgcatatg cagcagctca
    10381 ggttaaaaaa gctatggaaa taactaagta cttaggagga gaaaattttg tattctgggg
    10441 tggaagagaa ggttatgaaa ctttacttaa cactaataca gaacttgaaa tggataactt
    10501 tgcaagattc ttacaaatgg ctgtagacta tgctaaggaa ataggattca ctggacaatt
    10561 cttaatagag cctaagccaa aagagcctac taaacatcaa tacgattttg atactgctac
    10621 tgttttagga tttttaagaa agtataatct ggataaatac ttcaaaatga atatagaagc
    10681 aaaccatgca acacttgcag gacatacttt ccaacatgaa ttaaatatag caagaataaa
    10741 caatgtttta ggtagtatag atgcaaatca aggagaccta ttattaggtt gggatacaga
    10801 ccaatttcca acaaatatat atgatgcaac acttgctatg tatgaagtgt taaagcaagg
    10861 tggaatagca ccaggagggt ttaattttga ctctaaagta agaagagcat cttttgaggt
    10921 agaagactta ttcctagctt atattgcagg aatggataca tttgcaaagg gattattaat
    10981 agctcataaa ttattagaag atgaggtatt tgaaaacttt actaaagaaa gatatgcaag
    11041 ttttagtgaa ggtataggta aggatatagt agaaggtaag gttggattta aagagttaga
    11101 atcttatgca ctgcaaatgc cagttataaa gaataagtct ggaagacaag aaatgctaga
    11161 agctatactt aacagatata tatatgaagt agatacaatt tctaataagt aattgtgtag
    11221 taattaaact tggatgtttg aataaaataa caggatatgt tcttgttttt attctaaaac
    11281 ggacaaagat aagtatttgt aaaaattctc ataatcatga taaattaagg atatagactt
    11341 aagtataatt agtttatatc cttaaaattt ctat
//
LOCUS       DAYAOO010000113        11366 bp    DNA     linear   BCT 12-OCT-2024
DEFINITION  TPA_asm: Clostridioides difficile isolate ST8-SSI-h139-18
            SAMN40601845-rid21577343.denovo.115, whole genome shotgun sequence.
ACCESSION   DAYAOO010000113 DAYAOO010000000
VERSION     DAYAOO010000113.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN40601845
            Sequence Read Archive: SRR28438827
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 11366)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11366)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-MAY-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-MAY-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002157583.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002157583.1
            Genome Coverage       :: 163x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/11/2024 16:19:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 4,038
            CDSs (total)                      :: 3,963
            Genes (coding)                    :: 3,930
            CDSs (with protein)               :: 3,930
            Genes (RNA)                       :: 75
            rRNAs                             :: 6, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 60
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 33
            CDSs (without protein)            :: 33
            Pseudo Genes (ambiguous residues) :: 0 of 33
            Pseudo Genes (frameshifted)       :: 7 of 33
            Pseudo Genes (incomplete)         :: 25 of 33
            Pseudo Genes (internal stop)      :: 11 of 33
            Pseudo Genes (multiple problems)  :: 8 of 33
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11366
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN40601845-rid21577343.denovo.115"
                     /isolate="ST8-SSI-h139-18"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Denmark"
                     /collection_date="2018"
                     /collected_by="Statens Serum Institute"
     gene            284..1456
                     /locus_tag="ACGI5H_003448"
     CDS             284..1456
                     /locus_tag="ACGI5H_003448"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437640.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GHKL domain-containing protein"
                     /protein_id="HFG9699136.1"
                     /translation="MIIWLSDPINILFTLFGYFILLIICSKSKLIPIISVVMILYPII
                     IGLNFLFINNPIYEELIHSKEYILILSIVQIISALIKLLFWFLIHIFLKNRLVNIKQY
                     LSNKIWIFIDMVCISSFLSILIAIILPPTNLIPMGSNKNIILGNLPYGTYLIILSAIL
                     ANIGVILLLQPLIENVKMKIEKQANHLKEKYYNLLENQQIQIRKMRHDMNNHFQMIES
                     YLEIEDIAGAKKYFNQLKIGIGTLSGKQFCKNQALNSILNLRHTSLEENGVDVHFNID
                     IDNHLGIEPIDLCTIFSNSLDNAIEASLKIPDLSNRKVVLKARCEKEYFSYLLTNNKV
                     NPINRKQELFISDKKDSNSHGYGIENIREIVNKYNGKLDISYTESEFSLFLYIRLF"
     gene            complement(1792..2361)
                     /locus_tag="ACGI5H_003449"
     CDS             complement(1792..2361)
                     /locus_tag="ACGI5H_003449"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860876.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GrpB family protein"
                     /protein_id="HFG9699137.1"
                     /translation="MKKKLEDMTLEELWNLFPIFLTTHKECWKNWFKEEQYRLTGILP
                     MQKIVRISHIGSTSVSTIYAKPIVDILIEIIPDYNMKDIKDLIESNGYICMSESSSRL
                     SLNKGYTVEGFEERVFHLHIRYVGDNDELFFRDYLIDHPDVAKEYEKLKLDLWKKYEH
                     NRDAYTDSKLDFVREFTEKAKVLYSNRYN"
     gene            2764..3336
                     /locus_tag="ACGI5H_003450"
     CDS             2764..3336
                     /locus_tag="ACGI5H_003450"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860875.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="urea carboxylase-associated family protein"
                     /protein_id="HFG9699138.1"
                     /translation="MEYIINPCSGIKIKITRGQKIEIVDIEGGQVVDFFAEMKDDSTE
                     FISPGVTIDCNESLRLQVGNLIYSNKYRPMFKILYDDVREHDLLHPCCRPEMYDFFYH
                     NGENHPNCFDNINRTLGTSHQIIHPINLFMYTKVNTDGSIEVCEPLSKANDKIILEAL
                     ENMTLGIAACSVSESSCNSRKCTSIKILVD"
     gene            complement(4015..4917)
                     /locus_tag="ACGI5H_003451"
     CDS             complement(4015..4917)
                     /locus_tag="ACGI5H_003451"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895617.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0005247 - voltage-gated chloride channel
                     activity [Evidence IEA];
                     GO_process: GO:0006821 - chloride transport [Evidence
                     IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="chloride channel protein"
                     /protein_id="HFG9699139.1"
                     /translation="MLPQDYYGLIVILGVILGVMGAFYNWFTLYVQSLYKKIPKIGTF
                     GKLLIPFIMAGILGLVMPDVLGSGHNLVEELTSHKYIFGMVVLIFVIRFIFSAVSFGS
                     GAPGGIFFPLLVLGAFIGGIFGMVGVKVFGMNPDYVNNFVLLAMAGYFTAIVRAPLTG
                     IILIFEMTGSVSQMLSLSVISIVAYIVATLMKSKPIYESLLERLLEKNGEPVHKERGE
                     KILDQFSVMFGSPVANKAIQDVQWPENCLLVAIQRGGEEIIPRGKTILRPSDVIVTMT
                     DERDSGAVYDKMENLCKEHTAHIF"
     gene            complement(5044..5163)
                     /locus_tag="ACGI5H_003452"
                     /pseudo
     CDS             complement(5044..5163)
                     /locus_tag="ACGI5H_003452"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888399.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="zinc ribbon domain-containing protein"
     gene            complement(5706..6299)
                     /locus_tag="ACGI5H_003453"
     CDS             complement(5706..6299)
                     /locus_tag="ACGI5H_003453"
                     /inference="COORDINATES: protein motif:HMM:NF012861.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0005247 - voltage-gated chloride channel
                     activity [Evidence IEA];
                     GO_process: GO:0006821 - chloride transport [Evidence
                     IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="chloride channel protein"
                     /protein_id="HFG9699140.1"
                     /translation="MVGAVAGLIVLLYRILLGQAGTWLSQILKFVEGSTIKIIAWFAV
                     LAVLAWIVSKLVDWEPMISGSGIPQLEGEMTGKIKQVWWRVLPTKFIGGFLSLMGGLA
                     LGREGPSIQLGAMAGKGISRALDRGKTEEKFLLTCGASAGLSAAFHAPLAGVMFSLEE
                     VHKNFSVSVLISVMTASLTADYISANFLGMESVFQFD"
     gene            complement(6531..7067)
                     /locus_tag="ACGI5H_003454"
     CDS             complement(6531..7067)
                     /locus_tag="ACGI5H_003454"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438861.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GrpB family protein"
                     /protein_id="HFG9699141.1"
                     /translation="MIGLKCGMVKLLEHQMIWDKSAKDVIILLKSIWDKTAIDIQHIG
                     STSIPSISAKPIIDIVVGVASLEEAKLYLERLEQCGIVFRGQDVPKQLLFAMGDFEKN
                     TRTHHIHVVEWNSVAWNNYINFRDYLNTFTDKAKLYDSHKQKLALQFEDNRKIYTQRK
                     QELINILLEEARLWRINT"
     gene            complement(7140..7553)
                     /locus_tag="ACGI5H_003455"
     CDS             complement(7140..7553)
                     /locus_tag="ACGI5H_003455"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003507530.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3795 domain-containing protein"
                     /protein_id="HFG9699142.1"
                     /translation="MKMPKESIDTIMFAPCGMNCMVCYKHCYHKKPCAGCLNGDTGKP
                     EHCRKCKIKDCVCQKGLFYCFECFNFPCKLIKNLEKSYNKRYQASLMENSKFVQQYGL
                     EKFMQKQKERYTCSKCGGIISIHDRECSECQEKVK"
     gene            8019..8573
                     /locus_tag="ACGI5H_003456"
     CDS             8019..8573
                     /locus_tag="ACGI5H_003456"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729449.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="plasmid stabilization protein"
                     /protein_id="HFG9699143.1"
                     /translation="MDEKILELLQEMQGNISNMQGSISGIEGTISDMQSNINGIEDTI
                     SGMQGTISDMQGSISSMNGTISDMQGSISSMDGTINSMQDSITDMQVEIKEVNSRLDN
                     MEPDIKDLKTGQVETSSRLDTIQSDVTEIKSDVKINRNTLDTVIKHTSSLVKDTSDIK
                     NDLNNIEIVTSKNSNDIAKLKSVK"
     gene            complement(9181..9384)
                     /locus_tag="ACGI5H_003457"
     CDS             complement(9181..9384)
                     /locus_tag="ACGI5H_003457"
                     /EC_number="2.1.-.-"
                     /inference="COORDINATES: protein motif:HMM:NF019846.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008168 - methyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:1904047 - S-adenosyl-L-methionine binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HFG9699144.1"
                     /translation="MCLDAVIYMLQTGKQGADKKYLDNMFFVKGYVEELLFLDNSYDI
                     VFSCIVFHHCTNVQNIFCIFWKW"
     gene            complement(9586..10119)
                     /locus_tag="ACGI5H_003458"
     CDS             complement(9586..10119)
                     /locus_tag="ACGI5H_003458"
                     /EC_number="2.1.1.63"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895614.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003908 -
                     methylated-DNA-[protein]-cysteine S-methyltransferase
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="methylated-DNA--[protein]-cysteine
                     S-methyltransferase"
                     /protein_id="HFG9699145.1"
                     /translation="MQYISYYHSPIGNILLASDNIGLTGLWFENQKYYAYNLDQEHQE
                     KELPIFEQTKKWLDIYFSGKEPNFTPSLHMVGTPFQTTVWKILQQIPYGKTITYGEIA
                     YKVAQQKGISKMSAQAIGGAVGHNGISIIIPCHRVVGTNGSLTGYAGGIDRKIKLLSL
                     EKVSVQHYFIPKKGSAL"
     gene            10886..11074
                     /locus_tag="ACGI5H_003459"
     CDS             10886..11074
                     /locus_tag="ACGI5H_003459"
                     /inference="COORDINATES: protein motif:HMM:NF024242.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0043565 - sequence-specific DNA binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HFG9699146.1"
                     /translation="MPYKYFTEFCLLKATQFLKGTNELISDIAIKVVFHQIIYFSKCF
                     KEKTGYSPKVYRNIKKEI"
BASE COUNT         4061 a         1903 c         1366 g         4036 t
ORIGIN      
        1 tagaatttta tttttcaaaa tcaattcttt gaaatctaat ttccagaatt ttaattttta
       61 agatttaatt ttttaaaact tagtttccag aatcttaatt aatagaaagg tatattaaat
      121 gggcacttat tctttaatct ctacaagcat aaattttatt ctaatattaa tcaatatttt
      181 catagccttt tttctttata agttgacttc ctattttata gactttagga atcattggat
      241 tttcaaaatc atattgattt tgggctactc tattattagt caaatgataa tatggctttc
      301 cgaccccata aatattttgt ttacactatt cggatatttt atactactta taatatgtag
      361 caaaagcaaa ttaattccta taatatcagt tgtcatgata ctttatccta ttataattgg
      421 gcttaatttt ctttttataa acaaccctat atatgaggaa cttatacact caaaagagta
      481 tattttaata ctttcaatag tccagataat ttctgctcta attaaattat tattttggtt
      541 tttaatacat attttcctaa agaatagatt ggtcaatata aaacaatact tatcaaataa
      601 aatatggatt tttattgata tggtatgtat atcttcattt ttatcaatat taattgctat
      661 tattctgcca cctactaatt taatccctat gggtagtaat aagaatatta tcttaggcaa
      721 cttaccttat ggcacttatc taatcatctt gtcagcaatt ctggcaaata tcggtgtgat
      781 acttctttta cagccattga ttgaaaatgt aaagatgaag atagaaaaac aagcaaatca
      841 cctaaaagaa aaatactata acttactaga aaatcaacaa attcaaatac gcaaaatgcg
      901 acatgatatg aataatcact ttcaaatgat tgaatcgtat ttagaaattg aagatattgc
      961 tggagctaaa aagtatttta atcagttaaa aataggtata ggtactctta gtggaaaaca
     1021 attttgcaaa aaccaagctc ttaactcaat tttaaatctt cgtcatacaa gtttagaaga
     1081 aaatggtgtt gatgtgcact ttaatataga tatagacaat cacttgggta tagaacctat
     1141 agatttatgt actatttttt caaattcttt agataacgct atagaagcat ctttgaaaat
     1201 tcctgatttg tcaaatagaa aagtggtatt aaaggcacgt tgtgagaagg agtattttag
     1261 ctatttattg acaaacaaca aggtaaatcc tatcaataga aaacaagaac tatttatttc
     1321 agataaaaaa gatagtaatt ctcacggata tggtattgag aatattagag aaattgttaa
     1381 taagtacaat ggaaaattgg atatttctta tactgagagt gaattttctt tatttcttta
     1441 tattagatta ttttagtcta aaattagatt atcttatata atacaaatta gattgtttga
     1501 tactatgtaa aattataata acttataatt aaatatttac acatatattc attaacttaa
     1561 aatttaatca aatgtgatat tttatttacc ttagtaaaaa tgtgtgtgtc tcaaaataaa
     1621 ctttttagtt gatgaggcac tcttttttac atgaaatcaa atatattttt atcctttcaa
     1681 caatgaaaaa tggatttatc tctccatttt gaaacaagcc ctttttctat taattacttt
     1741 cttaaaaaat ataatacgat atataagata aatatctaat tgtacctatt tctaattata
     1801 tctattagaa tacaacacct ttgccttttc agtaaactcc ctaacaaaat ctagtttact
     1861 atctgtataa gcatcacgat tatgctcata cttcttccaa aggtccaact taagtttttc
     1921 atactccttt gcaacatctg ggtggtcaat taagtaatct ctaaaaaaca actcatcatt
     1981 atcacctaca taccttatat gcaaatgaaa aactcgttct tcaaacccct ctactgtata
     2041 ccctttatta agtgaaagcc tactactgct ctcagacata caaatatatc cattcgactc
     2101 aatcaaatct ttaatatctt tcatattata atcaggaatt atctcaatca gtatgtcaac
     2161 aatgggcttg gcataaatcg tactcacaga agtacttcca atatgactta ttctaacaat
     2221 tttttgcatt ggcaatattc cagttagtct atattgttct tctttaaacc aatttttcca
     2281 acattctttg tgagtagtca aaaatatagg aaacaagttc cataactcct ctaaagtcat
     2341 atcttccaac ttctttttca ttagttacct ccttttaaat ttgtacttta tattttttct
     2401 ttttcaaatt tacttagtta atatttaact ttatttttta tcaaatcatt tttctaatta
     2461 tgtaaatttt tctaaattta gtttttaatg tattataaca gatttttacc cttcttacac
     2521 ttttgtatct atttaaatat tagaacattt tttcttactt ctaaatacag taagattgct
     2581 taaataccaa ataggagcaa aaaaactctg taatctaaaa aaaactacaa catctttatg
     2641 agaattaaaa aatgatagac tatgttatca acattaagaa acagatagaa aagaaacaga
     2701 gtatgtgcta aaatgggaac atagaacaga atgacaaatt ggaatttatg gaggacatta
     2761 aatatggagt atataatcaa tccttgtagt ggtataaaaa ttaaaataac tagagggcag
     2821 aaaattgaaa ttgtggatat tgaaggagga caggtcgttg atttttttgc agaaatgaaa
     2881 gatgattcaa ctgaatttat atctccaggt gttacaattg attgtaatga gtcattaaga
     2941 ttacaagttg ggaatttaat atattctaat aagtatagac ctatgtttaa aattttatat
     3001 gatgatgtaa gggaacatga cttgctacat ccatgttgta gacctgagat gtacgatttc
     3061 ttttatcaca atggagaaaa tcatccaaac tgttttgata atattaatcg cacacttgga
     3121 acttcccatc aaattattca ccccattaat ttgtttatgt acacaaaagt caatacagat
     3181 gggagtattg aagtatgtga acctttatca aaagccaatg acaaaattat tcttgaagca
     3241 ttggaaaaca tgactttagg gattgctgca tgcagtgttt cagaaagttc ttgtaatagc
     3301 agaaaatgta cttctattaa gattttggtt gattgacaaa tttcatttat cgaaaaaata
     3361 tcaaaattaa aaaatgacgt caaaggcgca aaagggtaac cacttgcgct ctcaattcat
     3421 tatggtttgt tacgtattta tgggtaaaaa tcccttgatt ctatgatgtt tttcagacac
     3481 aattacaaat gagtaaggat tttatactca tactctaaaa aatagcattt tattgcgtaa
     3541 cagaacgaaa aaacagtgtg tacctttttc ttgcaataca cactgtattc atagccactc
     3601 tagctgttaa ctgttaatta tctcataata cccttactgg tattcatcta atcttaaccc
     3661 cttttaatta ttttcattta taaataaatt ctattcttcc caaaatatcg taattaaaat
     3721 atattaatta aaatatccca ataagaatat ctgaaaaatc ttctacctat tttttcaaac
     3781 cttttattcc cattcctcat acaatagtgc aacttttagc acagtataaa tataccatta
     3841 gtccatataa tctcattaac aaatatatac aattattttc ttcaaactct tttatatcta
     3901 agatatcaca ttttcatttt cttatattaa ttccttaact ctctttcaaa ttaccaattt
     3961 tttaatcaaa tcttcattaa atattctatc attattaaac attcatcatt atccctaaaa
     4021 aatatgtgcc gtatgttctt tacacaaatt ttccatctta tcatacacag caccactatc
     4081 tctctcatct gtcatagtca caattacatc acttggtcta agaattgtct tacctctagg
     4141 aataatttct tctccacctc tttgaattgc taccaaaaga caattttcag gccactgtac
     4201 atcctgaatt gccttgttcg caacaggaga gccaaacata acagagaact ggtctagtat
     4261 cttttcgccc ctctctttat gtacaggttc tccattcttt tcaagtaacc tctcaagaag
     4321 actttcataa ataggtttag acttcataag tgtagccaca atatatgcca caattgaaat
     4381 tactgatagt gaaagcattt gactaacaga acctgtcatt tcaaaaatta atatgatacc
     4441 agtcaaaggg gcacgcacaa tagctgtaaa atatcctgcc atagccaaaa gcacaaagtt
     4501 atttacataa tcgggattca ttccaaaaac tttaacacct accataccaa atattccacc
     4561 tataaatgct cctaaaacaa gcaatggaaa aaatattccc cctggtgcac ctgacccaaa
     4621 actaacagcc gaaaatataa aacgtataac aaaaatcaaa acaaccattc caaaaatata
     4681 tttatgactt gtaagttctt caactaaatt gtgtccactc cccagaacat caggcataac
     4741 aagcccaaga ataccagcca ttataaatgg aatcaacagt tttccaaacg taccaatttt
     4801 aggaatcttc ttgtataaag actgcacata tagagtaaac cagttgtaaa atgcccccat
     4861 aactccaaga ataacaccta aaatcactat taatccataa taatcttgtg gcaacacatt
     4921 tccaatctga acctcccatg actaaagtca cagggttcct gcttcataga attttgcata
     4981 ctaaaatatg tcttactaat tctccacagg ctatccccgt agttcctacg gttcttacat
     5041 aagttattta ttttgaattg ttattagtct taatccttct tttaatatat ttatacttgc
     5101 atttatatct ctatcgtgag tttcattaca actaggacaa atccattctc ttataataat
     5161 gttaacaaat gtaattattt aaaacaatta tttagaaggt tttatattta attttaaata
     5221 acatatttaa gaaccgtaag tcttaacttt tatcattttt gaggttgtcg ttcacataag
     5281 ttcgctacta cctatgcagt tctcttatga acttcttaca ctttcatgca agcacagact
     5341 atatcttatc cttcggcatt atccgttaag gtctacccac ttccactacc aatagcttgt
     5401 agtgtacttc cctcaagagg aatagtcgtt gaagtttctc ctattcggag tttacctgct
     5461 gattgcccat tttaaagtac ttagggttta accttatacc atctaaccaa ttttttctac
     5521 tttcgtaact ttcacactta ggtttatttc atccttatgt tttagtttgg ttagctttag
     5581 gggtttccag caattcaagt agtattggat aggttctatc ctatctctac atataggttt
     5641 ccctatatgc tgactatttt agctactaac tcatgactaa agtcacaagt gttcgtagct
     5701 attttttaat caaactggaa tacagactcc attcctagga aattggctga aatatagtct
     5761 gctgtcaaag atgctgtcat cacagaaatt aaaacagata ctgaaaagtt tttatggact
     5821 tcttcaagtg aaaacataac acccgctagt ggtgcatgaa aggctgctga taatccagca
     5881 cttgccccac aggttaacag gaatttttcc tctgtcttcc ctcggtcaag agctctagaa
     5941 atacctttac ctgccatagc accaagctga atggaaggac cttcccttcc caaagcaaga
     6001 ccacccatga gtgataagaa tcctccaata aattttgttg gcaacactcg ccaccatact
     6061 tgttttattt tccctgtcat ttccccctca agctgaggga taccacttcc agaaatcatt
     6121 ggctcccagt ccaccaactt tgatacaatc cacgcaagta ctgcaagtac tgcaaaccaa
     6181 gctattattt ttattgtaga accttctaca aattttaaaa tttggctaag ccaagtacca
     6241 gcctgcccta aaagtatcct gtataaaagc acaatcaaac cagccacagc cccaaccata
     6301 agtccttcac caatcaaaat tacctgaaag tgctctgccc gtttgataat atgagatgta
     6361 tcctttttca tactattcct ccttcatcca ataattctac acaatctgaa tctccaatga
     6421 ctaaagtcat gagtgtgtac agatattttt taatcaacaa aaatagattt ttacttacta
     6481 aatataagaa aataattgct caatttctca ataaatgtga atttattctt ttaggtattt
     6541 attctccaca gtcgtgcttc ttccagcaaa atatttatta attcttgctt tctctgtgta
     6601 tagattttac gattgtcctc aaactgtaat gctaattttt gtttatgact atcatagagt
     6661 tttgctttgt ctgtaaaagt atttagataa tctcgaaaat tgatataatt attccatgca
     6721 acactattcc attcaacaac atgaatatgg tgagtacgag tatttttctc aaaatctccc
     6781 atagcaaaaa gtaattgttt tggtacatcc tgacctcgaa aaacgattcc acattgctct
     6841 aacctttcga ggtataattt agcttcctct aaagaagcaa cacctacaac aatatcaata
     6901 ataggctttg cgctaatact gggaatagaa gtgcttccaa tgtgttgaat atcaatagca
     6961 gtcttatccc atatactttt taataatata atgacatctt ttgcactttt atcccatatc
     7021 atctgatgtt ccaataattt aaccatacca cattttaaac ctatcactat ataccacctc
     7081 aatataatcc acctttatat atattacaat tttttctatc ttgataaata gtgatttagc
     7141 tatttcactt tttcttgaca ctcgctacat tccctatcat gaatagatat aattcctcca
     7201 catttagaac aagtatatct ctccttctgc ttttgcataa acttctctaa accgtactgc
     7261 tgaacaaatt tactattttc cataaggctt gcttgatatc tcttgttata acttttttca
     7321 agatttttta tgagtttaca aggaaaattg aaacattcaa aacaataaaa caaccctttt
     7381 tgacagacac aatcctttat tttgcactta cggcagtgtt ctggctttcc tgtatcgccg
     7441 ttcaaacaac cagcacatgg ctttttgtga taacaatgct tatagcaaac catacaattc
     7501 attccacaag gagcaaacat aatcgtatca atactctctt ttggcatttt cataacattt
     7561 tactcctttc aaaaatccaa tttgtcgaat tgttatatat tcatattgta acataaaaaa
     7621 tagctaaaaa attcatgcac tttcattgcc aataaatttt caaggaaata tgaaagttta
     7681 aaactaagaa taaaaagaga taaaaaggaa gctactaatc aaaatattca aacacaagta
     7741 atcaatataa ataacttaag gtatatttaa aagtatatga tattaccagc agttttaaat
     7801 acaaatataa ccacacatgc ctcaaaaaca cttattacag tatcttagaa acttagacaa
     7861 tacataagat tcattaataa aaaagttctc aatatagata tatttaacca tgttttgaat
     7921 agtagataat catatgatta aaaattaaat atgacatagc gtttgtggaa tataacacct
     7981 aaattatgtt ataataataa agcaggagtg tgatagtgat ggatgaaaaa atattagagt
     8041 tattacagga aatgcaaggt aatattagta atatgcaagg tagtatcagt ggtatcgaag
     8101 gcactattag tgatatgcaa agcaatatta atggtatcga agacactatt agtggcatgc
     8161 aaggcactat tagcgatatg caaggcagta tcagtagtat gaatggcact attagcgata
     8221 tgcaaggcag tatcagtagt atggatggca ctattaatag tatgcaagac agtattactg
     8281 atatgcaagt tgaaattaaa gaagtcaata gtaggttaga caatatggaa cctgatatta
     8341 aagacttaaa aactggacaa gttgaaacta gtagtagact tgatactatt cagagtgatg
     8401 ttacagaaat taagtcagat gtaaaaatta acagaaatac attagataca gtgattaaac
     8461 atacctcttc attagtaaaa gatacatcag atattaaaaa tgatttaaat aatatagaga
     8521 tagtcacatc taagaattcg aatgatattg ctaaattaaa atcagttaaa taatatacta
     8581 tagtaaaaaa tacctgaaaa tttcacatac ttctttaaag ttataccaaa ttttatacag
     8641 aaatactgat tatccgacaa cacactttac ttataaataa tttattaaaa aaatactcat
     8701 tttatcctaa aattaacacg actaaatgag tcttgatata ataataaaaa ataagggaga
     8761 ttgaacacta aaaagttgtg tatctccctt atattctata atatagttat ataatttttc
     8821 agcctaaaat aaaagtccat ctttgattaa aacacatccc cttatcactt ataaaaggat
     8881 aaaatcttgt tttcattttt ccatttatat cttcttgctt aagagtaata attttttctt
     8941 ttgatacttt aagtgattgg ttaaatttaa ccaaacgact aagttttgtt caacatctat
     9001 ttttcatatt ttccaatact taatctattt tttataaata attcttttat ttctaactca
     9061 cttacatttt ttacataaaa cgaagcatat aaatttcaac cttatcttgt atggttctta
     9121 atacttaatg agtagcttaa gtatcaatca ttataaattt ttcccttaca tttaacactc
     9181 ttaccatttc caaaatatac aaaatatatt ttgaacattt gtacaatgat gaaatacaat
     9241 acatgaaaat acaatatcat aactgttgtc taaaaataga agttcttcaa cataaccttt
     9301 cacaaaaaac atattatcta agtatttttt gtctgctcct tgttttcctg tttgtagcat
     9361 ataaattact gcatctaaac atataactac tcacacgaaa aaagaaaata aacttccaaa
     9421 atacaagctc taaaaactac ctctaaagtt gtataatgtt tactaggaat aaggttgtat
     9481 aacatatagt ttaaataatc attttttaaa attgcaagtt attgctttca aaattagatg
     9541 tttttatatc aaataaatga ttaagaattt ctaaatttaa tggctttata atgcactccc
     9601 tttctttggg ataaaataat gttgcacaga tactttttct aaagataaca attttatttt
     9661 tctatcaatt ccaccagcat acccagtcaa actcccattt gttcctacaa cacgatgaca
     9721 tggaataata atagagattc cattatgccc tactgcacca ccgattgctt gtgctgacat
     9781 tttagatatt cctttttgtt gagcaacttt atatgcaatt tctccataag tgattgtttt
     9841 accatatggt atttgttgta aaattttcca cactgtagtc tgaaaaggag tacctaccat
     9901 atggagtgat ggtgtaaaat tgggttcttt tcccgaaaaa taaatatcta accatttctt
     9961 tgtctgctcg aaaattggca attctttttc ttgatgttct tggtcaagat tataagcata
    10021 atacttttga ttctcaaacc aaagaccagt taacccaata ttatctgatg ctaaaagaat
    10081 atttccaatt ggactatggt aatagctaat atattgcata caattcctcc ttatattctg
    10141 aaaacttcac tcaaatcatt agacacttct tttctatcta ccattatgta aaaacatact
    10201 aatataattt ccttctaact acactttcgt tataatatct atcctcatat catattagtt
    10261 ttatatttac ctgcatctgt tcatcctttt ttccctttcc ctttgatgaa tataaaattc
    10321 atacatttaa gcttcctact gtattaactt ttatagaagt gtatattata attttatcac
    10381 taaataggcc aaaaaaatat cgatatagca tcaagtaata tcataatact ttcaaatggg
    10441 aaaagtaaga ataggctgta aaaaagaaaa gtatttttat gttagaaatc cagtaaaatc
    10501 attagtagat agaataacag aaaacgaaca atttgctatt tatcatttta cacataaata
    10561 taattgacgc aataaagtgt tttctattct acaacgatta ataaggttag aaaaaagtaa
    10621 aaatgaactg tatatgtatg aagcattagt ttctgtttct ttcctttggc ttattatgat
    10681 aaaaaatatt gttttgctac caataaaaca caaaaatata attaatatcc atatgcaaaa
    10741 aattttacgt tatattgaaa aatactattg ttttacatta tattgaaggg tactattgtg
    10801 aaaacttaat tttggagtac tatcaagcag tggtaatatc aataaatcag agtgctccag
    10861 atgatttgaa ctaagtttaa atactatacc ttataaatat tttactgagt tttgtttatt
    10921 aaaagcaact caatttctaa aaggcacaaa tgagctaata agtgacattg ctataaaagt
    10981 tgtttttcat caaataatct attttagtaa atgttttaaa gaaaaaacgg gatattctcc
    11041 aaaagtgtac agaaatataa aaaaagagat atgatttttt atttcttttg attatccaaa
    11101 gagtaaataa aaaatattgt aaaaaactta ctaacaacgg caatgctttg aactatggta
    11161 atactttgaa cttttgattg gacttttttt gctaaaataa tatatttaaa tagcaaagta
    11221 atctgtttaa tcaataaaaa ataagagata aaagaaatca actaaaactt ttacctctta
    11281 ttttgatagt ttatcagagc taatatttac actcttttta tttttgatac ttcattaaaa
    11341 atgatgctta ctctccattc actttt
//
LOCUS       DAYAOO010000114        11292 bp    DNA     linear   BCT 12-OCT-2024
DEFINITION  TPA_asm: Clostridioides difficile isolate ST8-SSI-h139-18
            SAMN40601845-rid21577343.denovo.116, whole genome shotgun sequence.
ACCESSION   DAYAOO010000114 DAYAOO010000000
VERSION     DAYAOO010000114.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN40601845
            Sequence Read Archive: SRR28438827
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 11292)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11292)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-MAY-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-MAY-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002157583.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002157583.1
            Genome Coverage       :: 163x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/11/2024 16:19:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 4,038
            CDSs (total)                      :: 3,963
            Genes (coding)                    :: 3,930
            CDSs (with protein)               :: 3,930
            Genes (RNA)                       :: 75
            rRNAs                             :: 6, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 60
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 33
            CDSs (without protein)            :: 33
            Pseudo Genes (ambiguous residues) :: 0 of 33
            Pseudo Genes (frameshifted)       :: 7 of 33
            Pseudo Genes (incomplete)         :: 25 of 33
            Pseudo Genes (internal stop)      :: 11 of 33
            Pseudo Genes (multiple problems)  :: 8 of 33
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11292
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN40601845-rid21577343.denovo.116"
                     /isolate="ST8-SSI-h139-18"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Denmark"
                     /collection_date="2018"
                     /collected_by="Statens Serum Institute"
     gene            52..471
                     /locus_tag="ACGI5H_003460"
     CDS             52..471
                     /locus_tag="ACGI5H_003460"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417291.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9699147.1"
                     /translation="MQIYFRVKAVGKRKPMLELTPFDVSDNINCLKEAISEIVSKNVL
                     EYNEKIPEKSIINFLTNEEIESQADIGKVGFGSIYNENKQSVEKAIEVALQAFEDGIY
                     KVLINEDVIEKLDSSINLKSGDIFTFIRLTLLAGRMF"
     gene            496..5553
                     /locus_tag="ACGI5H_003461"
     CDS             496..5553
                     /locus_tag="ACGI5H_003461"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417287.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4132 domain-containing protein"
                     /protein_id="HFG9699148.1"
                     /translation="MLERTRVEKNPKIIENFKNNFTKSSSKQYYDLAKSLWDCIENSS
                     YYYREPEDKFLNMIKKYYNCHYYEIKNMDELLSGPLKNALELIFTSEQVEELCQLIKR
                     KMDYTYSGGYYRKGYRSNKLVDYFRGIIRFISNYVDLIYYDFSVIDYLTLPNKVLYYD
                     SIMSDKIALEIDKGNQKVISALEEVIFGENQTALLTRQMIIGIMKSHSDKCYEMLSKL
                     LLAAKQQEGLRQQIVESLDEGTISASIYMLKTILDNNLERFSSVIRALDTWTGLGFSD
                     QKPGIIRKCLELSYKSLTDEKFRIESINSNDNLEIYFALWATATYNIYDSYSLIENLL
                     SCQEKYKKLVALYFLSHTESTYFKHSIASKNIKGDDLEILAWVITNFYVEGSVGYYYS
                     WQNRETNFDLSNTPIDKDFDARKEQFESLKHTLEILNSKTKSFSGSVFPWTWIEISSH
                     EILKCMMTLTAYDMNAQFIDVLMENCHLMSSDLRASLIVNFVNEPKTDRQREFLLECL
                     SDKSVSNRETVLSLLRKLELTDVELDKITNLLSLKTSSIRQTVIKILLEQDDSNLENI
                     ASSLIKSSNSQKCLGGLEIVNLLKDNTARQELYNKLILLIEDIDKSKKNTSQVQILID
                     NLLGKAKNDYCKENGFGIYNPENKVQIPEQFDFKDDSNSSSKLNKIISNISLSTREDS
                     VSVATKKEAKKILDTDINKIIKVYEKFDELITENADYEYEVERWSGNVDKVLLGYSTY
                     NLTPIKYKVSNDTLDNYPLAELWRETSKKLDLDYKLILDILFYSISTCGYNETEKSWF
                     SSIYSNVLDSKKQNKIYTKLEKLKFNGLTRKLLRVLLNEFDHKEIFNYCLEIYYKLRN
                     LLTIEQCKKQRVEFTKNYYRQNEYCPALNAPILNYWLDKAHSFIYDDISFTKFFYTTF
                     SNYQLLEYKFPFYTSINVFARAHELGLMTEEQVNREMISGYNASNIIRTLTNPRWAGD
                     TLEKYPWLKDNLKTVTNRIIEIESRRGDMPTEVSNLANNIQYFEGINYFVNILVALGK
                     ETFQRGYSYGSNYSKKDVLSSLLKNCYPTKEDDSKKLKSLLKNTDITELRLIESAMYA
                     PQWVNIIEKYLNWKGLKSTIWYFHAHINEGFSAQKESEVALFSPISPRSFIDGAFDVD
                     WFLDSYKTIGEERFNILYKSAKYITSGGNSHRRAQLYADATLGKLDKDMLMKEIETNR
                     NQDKLRSFSLLPMKKGDLKEATFRYEFIQKFAKESKQFGAQRRESESKACTIALENLA
                     RSAGFGDVNRMMWALETEKLNEVAHLFKPKDIDGTSIWIDVDENGKASTKVQKGNKSL
                     KSIPKAIAKHPYVLELKSVQKDLKSQYSRAKQSLEQAMKNEIVFTVKEIANIYKNPVI
                     CPLIKNLVWVCDDNIGYVYNDKSKFFICNIEGETYKLTAKNKLKLAHPVHLFESGKWS
                     EFQHDLFSKQIVQPFKQVFREYYRINSDELSEKTISRRYAGHQIQPKKTVALLRNQLW
                     TVDYEEGLQKVFYKENIVAKMFALADWFSPADIEPPTIETVEFFDRKTYKSLELASIP
                     PILFSEVMRDIDLVVSVAHAGGVDPETSHSTVEMRIAIAKELLLLLKINNVNFEGSHA
                     LIAGNLGEYSVHMGSGIVHKKGMGALNILPIHSQSRGKIFLPFADEDPKTAEIMSKIL
                     LLAEDSKIKDPSILSNL"
     gene            complement(5738..6475)
                     /locus_tag="ACGI5H_003462"
     CDS             complement(5738..6475)
                     /locus_tag="ACGI5H_003462"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434827.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LytR/AlgR family response regulator
                     transcription factor"
                     /protein_id="HFG9699149.1"
                     /translation="MIKVLICDDDKIVRDDIANIAKESGYVDYVKKVKDGIEAIEFIK
                     NEKIDLLIIDIDMPYKNGIDSAEEILSIDKDIHIVFVTGFADYSLESFKVHPIDFVVK
                     PFKKEKILDSINIAIDHINSHKIANNNFIEDTLFVYKIRKQIHMINFDDIVMFEKNSR
                     AINLHTKDEDIIKFYENFDDLKKRLPPNFFMTHRQYIVNLRFIHKVIPINKSSLEIRF
                     INFQENAILNKSLEKDFLYRFYRVKRF"
     gene            complement(6494..7429)
                     /locus_tag="ACGI5H_003463"
     CDS             complement(6494..7429)
                     /locus_tag="ACGI5H_003463"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434825.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GHKL domain-containing protein"
                     /protein_id="HFG9699150.1"
                     /translation="MDNNFVFPIVILTLFIFSNLIMNKYKFYKELDILKRGILTFFIS
                     CFALILFMEGTKYIQLRLGYSFLLEGVLNIILFLVLIILSFYTGFKVIRLINNNNEQE
                     YKLQKLDSKINHKDNIIIKLRSQKHDYLKHLQVVYSLLNTGLDEDAKEYIMNISNSFK
                     SKNSRYGKVSYLDAIASLKYEECLEKDISFDVYIQDFMDNLEIEPNDMSSVLLNIIDN
                     AIESLSTIKKEKKYIRLHAYEDEFQYIIAIKNNGPKIHNVESIFWNGFSTKEGQDRGY
                     GLHLVKNILDKYDYSILVNSDDFLTEFVILIPKYY"
     gene            7637..10213
                     /locus_tag="ACGI5H_003464"
     CDS             7637..10213
                     /locus_tag="ACGI5H_003464"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434823.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HFG9699151.1"
                     /translation="MKDNLKIVLRYIKSYKARSLAIVVSIILATSLVVGIGTLSRSAQ
                     QADVDRLKRELGTDHVYFKNIKKNQLKSIKSSKDIKNLGITSYYASTDVNEKLPINIL
                     YTNKNYLTSHSKLIKGRFPKASNEVVVEKWILNSMGLKPEINQNLTFKLYQKENPETF
                     KVVGILEDRFIEKKKGQCEIFSNLNESELNDFTTYIEFNEGSDINTNIDNIIKNAMLD
                     EKSIGRNSMLIESTMKNGTLDNSSKYVAIAMSLFAGIVIYSIYVISIYQRVQEYGVLR
                     AIGSTNFRIFKLMLYELFILALIAMPIGICIGMGGAQIFNRSVGNIQFEGNINVTPFV
                     IPDKIILLSIACTILIILIISFFTYLKIRRISPIDAIRKTFGADKNVTKVNYLISKLT
                     LNMSVTKSISAKNIFRNKKGFIIIVLSMSIGGIIVIKDNYKYSFLDVQNKSTQEQTYM
                     NADFILSNVYLNEIGNNTSFKDIKGFNDNQIDKIKNIDGIDKVKTASILNTRIEVNKI
                     NRLDYYEAINSTPYYKLNPLFIKNKTTGKYTLKQKLKGYNDEMIKSLEKYLVSGNINL
                     KKMKKENLAIVYVPEISKTQKYTKTFTPGEGTPAVDIKVGDTIKVKYPKGGMDTGLYE
                     SLKDNYEYLEYEFKVGAIISYPFADNGMYSGDDGVDVITSSEYLKKLTGVDKYNLVYA
                     DLNENANKKKINNLLGKIGSEVPGTTTVDMMVEKENSDKMTSRTMIYSYGIVAIMFII
                     SVLNIINNISYNLTSRTSEFGMLRAIGISERGFKNMILYEGILYGVLSSIITIVSGII
                     IQFKMYYMQGFVSYGLGFSIDYKIYILVVVANIIVGILATYIPSRKINKISIVEAINI
                     TE"
     gene            10225..10896
                     /locus_tag="ACGI5H_003465"
     CDS             10225..10896
                     /locus_tag="ACGI5H_003465"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895404.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HFG9699152.1"
                     /translation="MPILETINLGKIYGKKETSVHALKNANLKINKGEFVAIIGPSGS
                     GKSTFLHLVGGLERPSNGTIKVDGKDICCLSDKELARYRRQKVGFVFQQYNLIPVLNV
                     KENIELPLKLDNKKIDKEYIDDLINLLGLNERKNHLPNQLSGGQQQRVAIARALSAKP
                     SIILADEPTGNLDSKTTEEVMDLLKSSIKKYNQTLIIITHNENIARKADRIISIIDGE
                     LKLTL"
     gene            10923..11264
                     /locus_tag="ACGI5H_003466"
     CDS             10923..11264
                     /locus_tag="ACGI5H_003466"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434819.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9699153.1"
                     /translation="MLLILGNLNLNLDFDYRIIREENEDVDIFIDINYRSLDIDTDGS
                     NLFNSRIQFPFVRALILRLNKNNQCMTIHLLRDIDLFSAFANFEVDYTDSIINIKNQN
                     EKVILNKSIKK"
BASE COUNT         4393 a         1458 c         1668 g         3773 t
ORIGIN      
        1 ataaattttt aaatttctaa atacataatt aatattttgc gaggtgattt tatgcaaatt
       61 tattttagag ttaaggctgt tggcaaacgc aaacctatgc tagaacttac cccttttgat
      121 gtatctgaca acatcaattg cctaaaagaa gctatctctg aaattgtatc taaaaatgtt
      181 cttgaatata atgagaaaat cccagaaaaa tcaataataa acttcttaac taatgaagaa
      241 attgaatctc aagctgatat tggaaaagtt ggatttggct ctatttacaa tgagaataaa
      301 caatctgtag aaaaggcaat agaggtagcg ttacaggcat ttgaagatgg aatctacaaa
      361 gtgcttataa atgaggatgt tattgaaaaa ctcgattcct ctataaatct gaaaagtgga
      421 gatatattta cttttataag acttaccttg cttgctggaa gaatgtttta aaataaataa
      481 tttggaggta cataaatgtt agaacgtact agagtagaaa aaaatcctaa aataattgaa
      541 aattttaaaa ataattttac taaatcttct tcaaaacagt actacgactt agcaaagtct
      601 ctttgggact gcatagaaaa tagttcatac tattatagag aacctgaaga caaattctta
      661 aatatgataa agaaatacta caattgccac tactacgaaa ttaaaaatat ggacgagctc
      721 ctttctggac ctttaaaaaa tgcattagaa ttaatattta cttctgaaca agtagaagaa
      781 ctttgccaat taattaaaag aaagatggat tatacatatt caggaggata ttatcgtaaa
      841 gggtatcgct caaataaact tgtggattat tttagaggta ttataaggtt tatttcaaac
      901 tatgttgatt taatttatta tgatttttca gttatagatt atcttactct tccaaataag
      961 gtcttgtact atgactctat aatgagtgat aaaatagcac tagaaataga caaaggaaat
     1021 caaaaagtaa taagtgcttt agaagaagta atatttggag aaaatcaaac tgctctactt
     1081 acaagacaaa tgataattgg tatcatgaag agtcatagtg ataaatgcta tgaaatgctt
     1141 tctaaacttc ttttggcagc caaacaacaa gaaggactta gacagcaaat tgtagagagt
     1201 ttagatgagg gtacaatttc tgcatcaata tacatgttaa aaactatttt ggacaacaat
     1261 ttagagcgat ttagttctgt tataagagcc ttggatacat ggacaggact tggtttttca
     1321 gaccaaaaac ctggaataat acgtaaatgt ttagaacttt catataaatc attgactgat
     1381 gaaaagttcc gtatagaatc aattaatagc aatgataatc ttgaaattta ttttgcctta
     1441 tgggctactg caacttacaa catatatgac tcttactctc ttattgaaaa cttactttct
     1501 tgtcaggaaa aatataaaaa acttgtagct ctttactttt tatcgcatac agaaagtaca
     1561 tattttaaac attctatagc atctaaaaac attaagggtg atgatttaga gatactagca
     1621 tgggtaatta caaatttcta tgtagaaggt tctgttggct actactatag ttggcaaaac
     1681 agagaaacta attttgactt gtcaaacact cctattgaca aagactttga tgctagaaaa
     1741 gaacaatttg aaagtttaaa acatacttta gaaattttaa attcaaagac aaaatcattt
     1801 tcaggaagtg tatttccatg gacttggatt gaaatttctt ctcatgaaat acttaaatgt
     1861 atgatgactt taacagcata cgatatgaat gctcaattta tagatgtgct tatggaaaat
     1921 tgtcatctta tgagttcaga tttaagagct tcacttatag tcaattttgt aaatgaacca
     1981 aagacagata gacaacgtga atttttattg gaatgtttaa gtgataagag tgtttccaat
     2041 agagaaacgg tattgagtct acttagaaag cttgagctaa cagatgtaga attagataag
     2101 ataaccaatc tattgtcttt aaagacaagc tctattagac aaacagtaat aaaaatttta
     2161 cttgaacaag atgattcaaa tttggaaaat attgcttctt cactgataaa atcttcaaat
     2221 tctcaaaaat gccttggagg tcttgaaatt gtaaacttat taaaagacaa tactgctaga
     2281 caagaactat ataataagct tattttactt atagaggata ttgataaatc taaaaagaat
     2341 acatctcaag ttcaaatact aattgataat ttgttaggta aagcaaaaaa tgattactgc
     2401 aaagaaaatg gttttggaat atataaccct gaaaacaaag ttcaaattcc agaacaattt
     2461 gattttaaag atgattctaa tagctcatca aagcttaata aaattatctc aaatataagt
     2521 ttatctactc gtgaggattc tgtttctgta gcaacaaaaa aagaagcaaa aaaaattctc
     2581 gatacggata taaataaaat aataaaagtt tatgaaaaat ttgatgaact tattactgaa
     2641 aatgcagatt atgaatatga agttgaaaga tggtcaggta atgtagacaa agtactttta
     2701 ggttattcta cttataactt gactcctatt aaatataaag tttctaatga tactcttgat
     2761 aattatccat tagcagagct ttggagagaa actagtaaaa aacttgactt agattacaaa
     2821 ttaatacttg atatcttatt ttatagtata agtacatgtg gatataatga aacagaaaaa
     2881 agttggtttt catctatata ttcaaatgtc cttgactcta aaaaacaaaa taaaatatat
     2941 acaaaacttg aaaaacttaa atttaatgga cttacaagaa aacttttaag agttttacta
     3001 aatgagtttg accataaaga aatatttaac tattgtttag aaatatacta taaacttaga
     3061 aacttattga ctatagaaca atgtaaaaaa caaagagttg aatttactaa aaactattac
     3121 agacaaaatg aatactgccc tgctttaaat gcccctattt taaactattg gcttgataaa
     3181 gcacattcgt ttatttatga tgatatttct tttactaagt ttttctacac tacgttttca
     3241 aattatcagt tgctagaata taagtttcct ttctatacta gcataaatgt gtttgctcgt
     3301 gcacatgaat taggattaat gactgaagag caagttaata gagaaatgat aagtggatac
     3361 aacgcatcaa atataataag aacattgaca aatcctagat gggctggcga cacattagaa
     3421 aagtaccctt ggcttaaaga taatttaaaa actgttacaa accgaattat agaaattgaa
     3481 tcacgtagag gtgatatgcc aacagaagtg tctaatctag ctaataatat acaatacttt
     3541 gaaggtataa attattttgt aaatattttg gtcgctcttg gtaaagaaac tttccagaga
     3601 ggatattcat atggtagcaa ttattcaaaa aaagatgttt taagttctct acttaaaaat
     3661 tgctatccta ctaaagaaga tgattcaaaa aaattaaaaa gtttacttaa aaataccgac
     3721 attactgagt taagattgat agaatctgct atgtatgccc ctcaatgggt aaacataatt
     3781 gaaaaatatt taaactggaa gggtctgaaa agtacaattt ggtacttcca tgcacatata
     3841 aatgaaggct tctctgcaca aaaagaatca gaggttgctc tattctcccc tatttcacca
     3901 cgtagtttca ttgatggtgc atttgatgta gattggtttt tagattcata taaaactatt
     3961 ggggaagaaa gattcaatat actttacaag tcagctaaat atataactag tggtggtaac
     4021 tctcatagac gtgcacaact ctatgctgat gctacacttg gtaagcttga taaagacatg
     4081 ttgatgaaag aaattgaaac aaatagaaat caagataaat tgagaagttt ctctttactt
     4141 cctatgaaaa aaggagacct aaaagaagca actttccgtt atgaatttat tcaaaagttt
     4201 gctaaagaaa gcaagcaatt tggtgcacaa cgtcgtgaaa gtgaatcaaa agcttgtact
     4261 atagcgctag aaaatctagc tagaagtgct ggatttggag atgtaaatcg tatgatgtgg
     4321 gctcttgaga ctgaaaaact aaatgaagtt gctcatctat ttaaaccaaa agatattgat
     4381 ggtacttcaa tttggataga tgttgatgaa aacggaaaag catctactaa agttcaaaaa
     4441 ggcaacaagt ctttaaagag tataccaaaa gctattgcta aacatccata tgtacttgaa
     4501 cttaaatctg tccaaaaaga tttaaagagt cagtattctc gtgcaaaaca gagtttagaa
     4561 caagctatga aaaatgaaat agtatttaca gttaaagaaa ttgccaatat ctataaaaat
     4621 ccagttatct gccctttgat taaaaatcta gtatgggtat gtgatgataa tattggatat
     4681 gtttataatg ataagtctaa gttctttatt tgcaatatag aaggtgaaac ttataagttg
     4741 acggcaaaaa ataaattaaa acttgcacat ccagttcatt tgtttgaatc tggtaagtgg
     4801 agtgagttcc aacatgattt atttagtaag caaattgttc aaccatttaa gcaagtattc
     4861 cgtgagtatt atagaataaa cagtgatgaa ttatctgaaa aaactatatc tcgcagatat
     4921 gctggtcacc aaattcagcc aaagaaaact gtagcacttc ttagaaatca gctttggact
     4981 gtcgattatg aagagggatt acagaaagta ttttataaag aaaatatagt ggcaaagatg
     5041 tttgcacttg cagattggtt ttcaccagca gatatagagc ctcctactat tgaaacagta
     5101 gaattttttg atagaaaaac ttataaaagt ttagaattag cttctatacc tccaattcta
     5161 ttctcagaag ttatgcgtga tatagacctt gttgtaagtg tcgctcatgc tggtggtgtt
     5221 gaccctgaaa ctagccattc tactgtagag atgcgtatag caattgctaa agaactttta
     5281 ttattattaa aaattaacaa tgtcaatttt gaaggctctc atgctcttat agcaggtaat
     5341 ttaggtgagt attctgtgca tatgggttct ggtattgtac ataaaaaagg gatgggtgct
     5401 ttgaatatac ttcctataca ttctcaaagt agaggtaaga tattccttcc attcgctgat
     5461 gaagacccta aaactgctga gattatgtct aagatactat tacttgctga agatagtaag
     5521 attaaagacc ctagtatctt aagtaattta taagtataaa aactatctct aaaatatatt
     5581 ggactttctt aaaaaaatta gaaagtccaa tatatactat actgtaattt atatagatta
     5641 aatcataatt acaaataatt tttatataaa cttctcttat acattatctt tacggtactt
     5701 attatatcac acaaaaagta tttttcttct atcttcacta gaatctttta accctataaa
     5761 atctatataa aaaatctttt tctagagatt tgtttaatat ggcattttct tgaaaattta
     5821 taaaccttat ctctaatgaa gatttattta taggtataac cttatgtata aatcttagat
     5881 ttactatgta ttgtctatgg gtcataaaga aattaggagg taggcgtttt tttaaatcat
     5941 caaagttctc ataaaacttt attatatctt catctttagt gtgtagatta attgctcttg
     6001 aatttttctc aaacataact atatcatcaa aattaatcat atgtatctgc ttccttattt
     6061 tatatacaaa aagggtgtct tctataaaat tattattagc aatcttatgg gagttaatat
     6121 ggtctattgc tatgttaatt gaatcaagta ttttttcttt tttaaatggt ttaactacaa
     6181 aatctatagg atgcacttta aagctttcaa gactataatc agcgaaaccc gtcacaaata
     6241 ctatatgtat atccttatct atagaaagaa tttcttcagc agaatcaatc ccatttttat
     6301 atggcatatc aatgtcaata atcaataaat ctattttctc attttttata aattcaattg
     6361 cctctatacc atccttaact tttttaacat aatctacata tccagactct ttagctatat
     6421 ttgctatatc atctcttaca atcttatcat catcacaaat caaaactttt atcatagact
     6481 tttctcctcc taactaataa tattttggga ttaagattac aaattcagtt aaaaaatcat
     6541 cactatttac aagtatacta taatcatact tatctaatat atttttaact aaatgtagcc
     6601 catatcccct atcttgtcct tctttagtac taaatccatt ccaaaatata ctttcaacat
     6661 tatgtatttt aggaccatta ttttttatag ctataatata ctgaaattca tcttcatatg
     6721 catgtaatct tatatacttc ttttcttttt ttatagtaga caaagactct attgcattat
     6781 ctattatgtt taatagtact gaactcatat cattaggttc aatctctaaa ttatccataa
     6841 aatcttgaat gtagacatca aaagatatat ccttttcaag acattcctcg tattttaatg
     6901 aagctatagc atctaaataa gatacttttc cataccttga attttttgat ttaaagctat
     6961 ttgatatatt cattatatat tctttggcat cttcatctag cccagtattt aatagagaat
     7021 acactacttg caaatgtttc aaatagtcat gtttttgact tcttaatttg ataattatat
     7081 tatccttatg atttatttta ctatctagtt tttgtaattt atattcctgt tcattattat
     7141 tatttatcaa tcttataact ttaaagcctg tataaaaact taaaataatt aaaaccaaaa
     7201 aaagtataat atttaatact ccttcaagta aaaaactata tcctaacctt aattgtatat
     7261 atttagtgcc ctccataaat aaaatcaatg caaaacacga tataaaaaat gttaatatgc
     7321 ctctttttaa tatgtctaat tctttgtaaa atttatactt attcattata agattgctaa
     7381 atataaacaa agttagtatt actataggaa atacaaaatt gttatccatg attcccctcc
     7441 cctctacaat ttatataggg attatatcat tttaaaaaaa ttatgtaaaa agttaaaatt
     7501 tacatatata ttaattaaac ttgtaaaaat acagatgaat ttgtacaatt aactacttaa
     7561 aatttgaaaa tacttacttt gctatatatt ttagataaat atataattga tttagttaag
     7621 aaaggaagtg gtaaatatga aagataattt gaaaatagta ctaaggtata taaaaagtta
     7681 taaagctagg tctttagcaa ttgttgtgag tataattctt gctacatcac tcgttgttgg
     7741 tattggtact ctctcaagaa gtgctcagca agcagatgta gatagattga aaagagagct
     7801 tggaactgac catgtatact ttaaaaatat aaagaaaaat caattaaagt ccataaaatc
     7861 tagcaaagat attaaaaatc tgggtataac atcttactat gcgtctacag atgttaatga
     7921 aaaattacct ataaacatac tatatacaaa taaaaattat ttgactagtc attctaaact
     7981 tataaaaggt cgatttccaa aagctagcaa tgaggtggta gtcgagaaat ggattttaaa
     8041 tagtatgggc ttaaaaccag agataaatca aaaccttact tttaaattat atcaaaaaga
     8101 aaatccagaa acttttaaag ttgttggaat ccttgaagat agatttatag agaaaaaaaa
     8161 gggacaatgt gaaatttttt ctaatctcaa tgaatcagaa ctgaatgatt ttacaactta
     8221 tattgaattt aatgaaggca gtgatataaa tacaaacata gacaatataa taaaaaatgc
     8281 tatgttagat gagaaaagta taggaagaaa ctcaatgctt atagaatcta ctatgaaaaa
     8341 cggtacttta gataattcaa gtaaatacgt tgcaattgct atgagtctat ttgctggtat
     8401 tgtaatatat agtatctatg ttatatcaat ataccaaaga gtacaggaat atggcgtctt
     8461 aagagctatt ggttccacca actttaggat tttcaaactt atgctttatg aacttttcat
     8521 acttgctcta atagcaatgc ctataggtat atgtataggt atgggaggtg cacaaatatt
     8581 taataggtct gtaggaaata ttcaatttga aggaaatata aatgttacac cttttgttat
     8641 tccagataaa ataattctct tatcaattgc atgtacaata ctaataatac taattataag
     8701 tttctttaca tacttaaaaa taagaagaat ttctcctatt gatgctatca gaaaaacttt
     8761 tggagctgat aaaaatgtaa ccaaagttaa ttatttaata tcaaaattaa ctttaaatat
     8821 gtcagtaaca aaatctatat ctgcgaaaaa catctttaga aataaaaagg ggttcattat
     8881 aattgtatta tctatgagta taggaggtat aatcgtcata aaagacaatt ataaatattc
     8941 ttttttagat gtgcaaaaca aatctactca agaacaaaca tatatgaatg cagattttat
     9001 tctatcaaat gtttatctca atgaaattgg taacaatact tcttttaaag atataaaagg
     9061 gtttaatgat aatcagatag ataaaataaa aaatatagat ggaattgaca aagtcaaaac
     9121 tgctagtatc ttaaacacaa gaatagaggt aaataaaata aatagattag attactacga
     9181 agctataaat tcaactcctt attataagct aaatcctctg ttcataaaaa ataagactac
     9241 tggcaaatat acactaaagc aaaagctaaa aggttataat gatgagatga taaagtcatt
     9301 agaaaaatac ttagtaagtg gaaatataaa cttgaaaaaa atgaaaaaag aaaatttagc
     9361 tattgtatat gtaccagaaa tttctaaaac acagaaatac acaaagactt ttactcctgg
     9421 tgaaggaaca ccagctgtag atataaaagt aggtgatact ataaaagtca aatatccaaa
     9481 gggtgggatg gatacaggtc tttatgaaag tctaaaagat aattatgaat acttagaata
     9541 tgaatttaaa gttggagcta ttataagtta tccttttgca gataatggta tgtactctgg
     9601 agatgatggt gtagatgtaa taacgagtag cgaataccta aaaaaattaa ctggtgtaga
     9661 taagtataac ttagtttatg cagaccttaa tgaaaatgca aacaagaaaa aaataaataa
     9721 ccttttaggt aaaattggaa gtgaagttcc tggaactaca acagtagata tgatggtaga
     9781 aaaagaaaat tctgataaga tgacatctag aactatgatt tatagttatg gtatagtagc
     9841 aataatgttc ataatcagtg tacttaacat aataaacaac ataagttata acttaacttc
     9901 aagaactagt gaatttggaa tgttaagagc tattggtatc tctgagagag gctttaaaaa
     9961 tatgatactt tatgaaggaa tattatatgg tgtactctca agtataatta ctatcgtgtc
    10021 aggaattata atacaattta aaatgtatta tatgcagggc tttgtatcat atggattggg
    10081 attttcaata gattacaaaa tatatatact agttgttgta gcaaatataa ttgtaggtat
    10141 tctagctaca tatattccat caagaaagat aaataaaatt agtatagttg aagctataaa
    10201 cattacagaa taggaggaat aattatgcct atattggaaa ctattaactt aggtaagatt
    10261 tatggaaaaa aggaaacatc tgtacatgca ctaaagaatg caaatttaaa aataaataaa
    10321 ggcgaatttg ttgctataat tggaccaagt ggaagtggga aaagtacatt tctacattta
    10381 gtaggtggtc ttgaaagacc aagtaatggt actataaagg tagatggtaa agatatatgt
    10441 tgtctttcag ataaagaatt agcaagatat agaagacaaa aggtaggatt tgtctttcaa
    10501 cagtataact taattcctgt attaaatgta aaggaaaata tagaattacc actaaagtta
    10561 gacaataaaa aaatagataa agaatatatt gatgacctta taaatttatt gggtcttaat
    10621 gaaaggaaaa atcatcttcc caaccaatta tctggtggtc aacagcaaag agttgctatt
    10681 gcacgtgctt tatctgcaaa accaagtata atcctagcag atgaaccaac aggaaatttg
    10741 gacagtaaaa ctacagaaga agtcatggat ttactaaaaa gttctataaa aaaatataac
    10801 caaacactta taataataac acataatgaa aatattgcta gaaaagcaga tagaattata
    10861 tctataatag atggagagct taaattaaca ctctaaaact atttatagaa aagaggattt
    10921 aaatgttatt gattttaggt aatttaaatt taaacttgga ttttgactac agaataataa
    10981 gagaagaaaa tgaagatgta gatatattta tagatattaa ttatcgtagc ttagatatag
    11041 atactgatgg ttctaactta tttaattcta gaatacaatt tccatttgta agagcattga
    11101 ttctaaggct aaataagaac aatcaatgta tgacaattca tttgttaaga gatatagatt
    11161 tattctctgc ttttgccaac tttgaagtgg attatactga ctctataata aatataaaaa
    11221 atcaaaatga gaaagtaatt ttaaataaat ctatcaaaaa atagtaaggg ggccttaata
    11281 ggccccaatt tt
//
LOCUS       DAYAOO010000115        11154 bp    DNA     linear   BCT 12-OCT-2024
DEFINITION  TPA_asm: Clostridioides difficile isolate ST8-SSI-h139-18
            SAMN40601845-rid21577343.denovo.117, whole genome shotgun sequence.
ACCESSION   DAYAOO010000115 DAYAOO010000000
VERSION     DAYAOO010000115.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN40601845
            Sequence Read Archive: SRR28438827
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 11154)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11154)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-MAY-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-MAY-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002157583.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002157583.1
            Genome Coverage       :: 163x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/11/2024 16:19:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 4,038
            CDSs (total)                      :: 3,963
            Genes (coding)                    :: 3,930
            CDSs (with protein)               :: 3,930
            Genes (RNA)                       :: 75
            rRNAs                             :: 6, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 60
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 33
            CDSs (without protein)            :: 33
            Pseudo Genes (ambiguous residues) :: 0 of 33
            Pseudo Genes (frameshifted)       :: 7 of 33
            Pseudo Genes (incomplete)         :: 25 of 33
            Pseudo Genes (internal stop)      :: 11 of 33
            Pseudo Genes (multiple problems)  :: 8 of 33
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11154
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN40601845-rid21577343.denovo.117"
                     /isolate="ST8-SSI-h139-18"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Denmark"
                     /collection_date="2018"
                     /collected_by="Statens Serum Institute"
     gene            <1..678
                     /locus_tag="ACGI5H_003467"
     CDS             <1..678
                     /locus_tag="ACGI5H_003467"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891723.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HFG9699154.1"
                     /translation="NFLINPEDAFDYIIFYIFILLIIYVAIAAPTFSGEYQTQSDSIL
                     RCTKHGHICLAFTKILALFSIFIIMFVICISIYLAISDLAFGTECLKTSFQMLFSVIS
                     LVNINLLQAQILIAIGGLISILAMVSLTLFLSAKCKDSLTSMLIAFSICLIPMGIGVS
                     WIGYLLPPGGIGFKISLLYQMTSFNFLHLGGMSFWTPHIILFFSVIEIPIFIFLAIHT
                     YCKHQVS"
     gene            1059..1976
                     /gene="pstC"
                     /locus_tag="ACGI5H_003468"
     CDS             1059..1976
                     /gene="pstC"
                     /locus_tag="ACGI5H_003468"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903680.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0015415 - ATPase-coupled phosphate ion
                     transmembrane transporter activity [Evidence IEA];
                     GO_process: GO:0006817 - phosphate ion transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter permease subunit PstC"
                     /protein_id="HFG9699155.1"
                     /translation="MIVKSRLVGLEKNDNNGNKTKYVIEKVAKNIFLLSALVAVASLL
                     LIIGFVFYKGLRPFIFEGYSFIDFLTGADWVPSANKFGISSMIVASIFATLGALVIGV
                     PVGILTSVFIAEVAPKRLAKIMSPAVELLAGIPSVLYGVFGLAVIVPTIQSIFNLPKG
                     QSLLAIVIVLAVMMLPTIISVSETAIRAVPKAYKEGSLALGASKIETIFKVVLPAAKS
                     GVLAAVVLGVGRALGETMAVILVAGNSPVMPTAITDSVRPLTTNIALEMGYAFGTHQE
                     MLFATGVVLFTFILILNLVLNKLSNKAVN"
     gene            1978..2802
                     /gene="pstA"
                     /locus_tag="ACGI5H_003469"
     CDS             1978..2802
                     /gene="pstA"
                     /locus_tag="ACGI5H_003469"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422134.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0015415 - ATPase-coupled phosphate ion
                     transmembrane transporter activity [Evidence IEA];
                     GO_process: GO:0006817 - phosphate ion transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter permease PstA"
                     /protein_id="HFG9699156.1"
                     /translation="MRKFKENLLKSLVYLSALFTIVSLVVIVGFIFIKGIGNMNFNFL
                     FSNYSASGDGGILPMIITTLYTVVVSIVVATPIGILAAIYLQEYAKKGKAVTAIRFAT
                     ESLSGIPSIVYGLFGGIFFVVTLKMGYSIVAGSLTVAIIILPVIIRTTEEALKTVPQA
                     YRESSLALGATKFQTLYKVVLPSAIPGILSGVILSVGRIIGESAAILLTAGTVAKMPG
                     GIFDSARTLTVHSYLLTKESGDIATAASIGIVLIVIVLALNMLARFVAKKLNKANY"
     gene            2821..3585
                     /gene="pstB"
                     /locus_tag="ACGI5H_003470"
     CDS             2821..3585
                     /gene="pstB"
                     /locus_tag="ACGI5H_003470"
                     /EC_number="7.3.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003432349.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009898 - cytoplasmic side of plasma
                     membrane [Evidence IEA];
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0015415 - ATPase-coupled phosphate ion
                     transmembrane transporter activity [Evidence IEA];
                     GO_process: GO:0006817 - phosphate ion transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter ATP-binding protein
                     PstB"
                     /protein_id="HFG9699157.1"
                     /translation="MELIDKIKMSVKDLDLFYGDKQALKKINMDIKENKVTALIGPSG
                     CGKSTFIRTLNRMNDLIEDVTIKGNISVDGEDIYTSDDVINLRTKVGMVFQKPNPFPM
                     SIYDNVAYGPRTHGLRDKKQLDKIVEESLKGAAIWDEVKDRLKSSALGLSGGQQQRIC
                     IARAIAMRPEVILMDEPTSALDPISTLKVEELIEDLKKDYTIVIVTHNMQQAARISDE
                     TAFFLNGEVIEFSDTKTMFTTPVDKRTEDYITGRFG"
     gene            3613..4266
                     /gene="phoU"
                     /locus_tag="ACGI5H_003471"
     CDS             3613..4266
                     /gene="phoU"
                     /locus_tag="ACGI5H_003471"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003432348.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0006817 - phosphate ion transport [Evidence
                     IEA];
                     GO_process: GO:0030643 - intracellular phosphate ion
                     homeostasis [Evidence IEA];
                     GO_process: GO:0045936 - negative regulation of phosphate
                     metabolic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate signaling complex protein PhoU"
                     /protein_id="HFG9699158.1"
                     /translation="MVNNSLDISIDTLKEQTVLMMEKCEEAIEKSVTCMIEKDLEGAR
                     KVVEDDEEINKLREEIRDKSIELIVLKQPMARDLRFIYSLGNISIELERIGDYAANIA
                     REMLKIGGEAYIKELIDIPKMAKECKSMMSQTREALILFDASIAYDVGTKDDIVDGLY
                     EQVQIDCLKIMHENSNTIDQGVKLLLIGRYLERIGDHITNVCEKIIFAIEGKMVEIG"
     gene            4424..5293
                     /locus_tag="ACGI5H_003472"
     CDS             4424..5293
                     /locus_tag="ACGI5H_003472"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422131.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aromatic acid exporter family protein"
                     /protein_id="HFG9699159.1"
                     /translation="MKLQKMGMRTIKTGISVTLCMILGDYLVENMFYSLVACIISVQD
                     TVKGSLKTGINRVEGTILGGIIGFIFAIIKAGDPFLCGLGVMCSIYLCNLFKIKSVVV
                     ACVTFLAIHLGVGNSDPVYYSLHRVLDTSVGVLFGVLVNYYVARPNYLNSVIDEFKKI
                     EELSMLLIEDKILRKENLNVEKFEEEVEKLEEIYSKLIDELDYSLSETNIEKIENALR
                     ICREIHFHMQSIELLENKLYLKEHTYKYLKKTYNVDKLDWNIDEEKSPVFNYHLMKIM
                     IEIELLRKLNKSY"
     gene            5380..6816
                     /locus_tag="ACGI5H_003473"
     CDS             5380..6816
                     /locus_tag="ACGI5H_003473"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891715.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="[Fe-Fe] hydrogenase large subunit C-terminal
                     domain-containing protein"
                     /protein_id="HFG9699160.1"
                     /translation="MNTRNDNSKILEIYKMKLFGELVKAVWNDDIEDIENLPNKILNE
                     NLKDNLNNYFSGKFDKDTMVNLIRVTMGLDVTEDTDKNLKESLHEAVNLDEVKRPIIS
                     VISDACKYCDENNKEDESCKIRSKHINCNEEDVCSACGDCVSRCKLGAISDKIEFIPM
                     IKLLKDIKSPVYAIVAPAFVGQFGKDVSPGKLRTALKKIGFEDMIEVALAADMLTAKE
                     AYDYYEHMKKDEEGCFITSCCCPIWVSLIQNSFPQILENVSPSVSPMIACGRAVKILN
                     PDAKVVFIGPCMAKKKEAMLEDIKDAVDFVLTFKELQEIFDALELNPAIMDESNRVEA
                     SLSGRVYARTGGVSKAVKLSVRRIDKNIKFEEKAFEGTKECMDGLKKVLNKEIEATFI
                     EGMGCVGGCVGGPKRILSVEEGTKNVDEYSESTNMETPFDNLNVLQFLTSLGIKRVES
                     LGEKEEEKVKKIFSRDIKSNKKENKYKK"
     gene            6864..7691
                     /locus_tag="ACGI5H_003474"
     CDS             6864..7691
                     /locus_tag="ACGI5H_003474"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898389.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016810 - hydrolase activity, acting on
                     carbon-nitrogen (but not peptide) bonds [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide deacetylase family protein"
                     /protein_id="HFG9699161.1"
                     /translation="MKIKDNKAVFHVFIRIFLIAVLILTGTLLEEKINNVPVENISSK
                     GENTLELLSQSNTLGEIIYKASQEETKGPGATSEKVAYITIDDGPSKYTNALLDILKE
                     NDVKATFFMLNQNMKNHKEEVRRVLEEENSIGFHSVSHDIHKLYKSPEVTVGEFNTCN
                     NTLQEITGQSSKLIRLPYGSKPYMPEGSYNKLMANDYLIWDWNLDTQDWKSSTSQIVS
                     NILYYGRKRDELVVLIHEKEQSLNALNNIIRILKERGYTILPITENITPKNFWQENL"
     misc_binding    7987..8249
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            8325..10991
                     /locus_tag="ACGI5H_003475"
     CDS             8325..10991
                     /locus_tag="ACGI5H_003475"
                     /EC_number="6.1.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861890.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0004812 - aminoacyl-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0004832 - valine-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006438 - valyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="valine--tRNA ligase"
                     /protein_id="HFG9699162.1"
                     /translation="MENTNLSKTYNPKDFEARLYKKWMDEGYFKSKPNPDKKPFTIMM
                     PPPNITGQLHMGHALDHTLQDILIRWKRMDGYEAFWLPGTDHASIATEVKVVERIKKQ
                     EGKTKYEIGREEFLKRAWEWKDEFGGKISNQLKQLGDSCDWDKERFTMDEGCNEAVIE
                     FFVSLYEKGHIYRGNRIINWCPDCKTTLSDAEVEHEEHDGNFYHIKYPLKDSEDFLEI
                     ATTRPETMIGDTGIAVNPEDDRYKHLIGKTAILPLVGRELPIVADSYVDLEFGTGAVK
                     MTPAHDPNDFEVGLRHNLEQLNTMNEDGTMNEVCGKYEGMDRFECRKAIVADLKEQGY
                     LIKIKEHNHNVGTCYRCHTVVEPRLSEQWFVKMEELAKPAIDILKKGELEFVPDKFDK
                     TYLQWLENIRDWCISRQLWWGHQIPAYYCQECGEIVVARKMPDKCPKCGSTHFKQDED
                     ALDTWFSSALWPFSTLGWPNKTEALDYYYPTSVLVTGYDIIFFWVVRMAFAGMFCMNE
                     KPFDHVLVHGLVRDSQGRKMSKSLGNGIDPLEIIEQYGADALRFTLTTGNSPGNDMRF
                     YMERVEFARNFANKLWNASRFVFMNIDEDIIKNMTRESVKEDLTLADKWIISRANNIV
                     KEATNNMDKFDLGIALQKIYDFTWSEYCDWYIEMVKPRLYGEDANAKSAALYTLTYVL
                     EKILKLLHPYMPFITEEIYTHLPTVEGCIIVSEWPKYNEEDNMAEEEDMMNLLMEGIR
                     SIRNVRAEMNVPPSKKAKLIIIPSEEKIEAIELGKDYFITLASASNVEIAKDKSNVPE
                     DAVGVVIDGVEIFIPLNELVDFEKEIERLSKEKKKLEGEIKRVNGKLANQGFLAKAPE
                     SLIEEEKAKKEKFEEMIKSVEERLTNLESKIK"
BASE COUNT         4405 a         1196 c         2081 g         3472 t
ORIGIN      
        1 aatttcttaa taaatccaga agatgctttc gattatataa tattttatat ttttatatta
       61 ttaattatat atgttgcaat tgctgcacct actttttctg gtgagtatca gacacaatca
      121 gatagcatcc ttcgttgtac gaaacatgga catatttgtc tagcgtttac taaaatatta
      181 gctctatttt ctatatttat aataatgttt gttatatgta tttctatcta tttggcaatt
      241 tctgatttag cttttggtac tgaatgtttg aaaacctcat ttcaaatgtt gttttctgtc
      301 attagtctag taaatataaa tttactacaa gcacagattc ttatagctat tggtggtcta
      361 atttcaatac ttgcaatggt tagtttaaca ttatttttat ctgcaaaatg taaggattct
      421 cttacttcta tgctgattgc tttttctatt tgcttaattc ctatgggaat aggtgttagt
      481 tggattggat acctattacc gccaggggga attggtttta agattagttt attatatcaa
      541 atgacatcat ttaatttctt acacttagga ggtatgagtt tttggacacc acacattata
      601 ctgtttttct cagtgataga aatacctatt tttatatttt tggctattca tacctattgc
      661 aaacatcaag tatcgtaaca atttgatgga aataatagtg atataaacta gaggatacaa
      721 taattatata tgtagtataa aagttaaatt tagttaacaa atcttaatag cagatatagg
      781 taataaatta tacataaact gtattattat ctatatctgc tattttaata tagagaaaca
      841 acagtatatt gtaaagtaaa tgtcaaatat agttttaaaa gtaaaattaa tgttaaaaag
      901 taaatataat tttacacttg cttaacttaa tcctaatata gatttaactt aaaaaaagta
      961 gaataaaagt acaggaaatt tgatgaagac gaattataaa aaattaaatt ttgaatacag
     1021 aacgaaaatc gataagtata ttttaatggg agggtattat gatagtaaaa tctagattag
     1081 taggtttaga aaaaaatgac aataatggca ataagacaaa atacgtaatt gaaaaagtag
     1141 caaaaaatat ttttctactt agtgctttag tagcagttgc aagtttactt ttgataatag
     1201 gatttgtatt ttataaagga ttaagaccat ttatatttga aggatattca tttatagact
     1261 ttttaactgg tgcagattgg gttccttctg ccaataaatt tggaatatca tctatgatag
     1321 tagcatcaat atttgcaaca cttggagcac ttgttatagg agtacctgtt ggtatattaa
     1381 cctctgtatt tatagcagaa gtagcaccta aaagattagc aaaaataatg tcaccagcag
     1441 ttgaactttt agcaggtata ccttcagtat tatatggtgt atttggtctt gcagtgatag
     1501 ttccaactat acaaagtata tttaatcttc caaaaggtca aagtttgtta gcaatagtaa
     1561 tagtattagc agtaatgatg ttaccaacaa taatatctgt atcagaaaca gcaataagag
     1621 cagtaccaaa agcatacaaa gaaggttcat tagcacttgg tgcatcaaaa atagaaacaa
     1681 tattcaaagt tgtattacct gctgcaaaat ctggagtatt agccgcagta gtgttaggag
     1741 taggaagagc tttaggtgaa acaatggcag taatacttgt tgcaggcaac tcaccagtta
     1801 tgccaactgc aataacagat agtgtaagac cacttacaac taatatagca cttgaaatgg
     1861 gatacgcatt tggtacacat caagaaatgc tatttgcaac tggagtagta ttgtttacat
     1921 ttatattaat tttaaactta gttttaaata aactttcaaa taaggcggta aattaagatg
     1981 agaaagttca aagagaatct attgaagtca ttagtatatc tatcagcact atttacaata
     2041 gtatcattag tagttatagt gggatttata tttataaagg gaattggcaa catgaatttt
     2101 aatttcttat ttagcaatta ttcagcatca ggtgatggtg gtatacttcc aatgataatt
     2161 acaacattat atacagtagt agtttctata gttgtagcaa ctcctatagg aatattggct
     2221 gctatatatt tacaagaata tgctaaaaaa ggaaaagcag ttacagctat aagatttgca
     2281 actgaaagtt tatcagggat accatctata gtatatggat tatttggagg aattttcttt
     2341 gtagttacat taaaaatggg atattccata gttgcaggtt cacttacagt tgcaataata
     2401 atattaccag taataattcg tacaacagaa gaagctttaa aaacagttcc tcaagcttat
     2461 agagaatcat cattggcatt aggagctaca aaatttcaaa ctttatataa ggtagtactt
     2521 ccaagtgcaa taccaggaat tttatctgga gtaatcttat cagttggtcg tataattgga
     2581 gaatcagctg caatattact tacagcaggt actgtagcca agatgccagg tggaatattt
     2641 gatagtgcaa gaacattaac tgtacactca tacttactga ctaaagagag tggagatata
     2701 gcaacagcag ccagtatagg aattgtttta atagtaattg tattagcact aaacatgcta
     2761 gcaagatttg ttgctaagaa attaaataaa gctaattatt aaatttaaga ggtgtgaata
     2821 atggaattaa tcgataagat aaaaatgagt gtaaaagatt tggatttatt ttatggtgat
     2881 aagcaagcat taaagaaaat aaatatggat ataaaagaga ataaggttac tgctttaata
     2941 ggtccatctg gatgcggaaa atcaactttt ataagaacgt taaatagaat gaatgactta
     3001 atcgaagatg taacaattaa aggaaacatt tctgttgatg gagaggacat atatacctca
     3061 gatgatgtta taaatcttcg tactaaagta ggaatggtat ttcaaaagcc aaatccattt
     3121 cctatgagta tatatgataa tgtggcatat ggtcctcgta cacatggact aagagataag
     3181 aagcaattag ataaaattgt agaagaaagc ttaaaaggtg cagctatttg ggatgaggtt
     3241 aaagacaggc ttaaatcatc tgcactagga ctttctggtg gtcaacaaca acgtatatgt
     3301 atagcaagag caattgctat gagaccagaa gttattctta tggatgaacc tacatctgct
     3361 ttagacccaa tttcaacatt aaaagtagag gaacttatag aggatttaaa aaaagactac
     3421 acaatagtca tagttacaca taatatgcaa caagctgctc gtatatcaga tgaaacagct
     3481 tttttcttaa atggagaggt tatagaattt agcgatacaa aaactatgtt taccactcct
     3541 gtagataaaa gaacagaaga ctatataaca ggtagatttg gttaaaatat ataactataa
     3601 aggagttaga caatggtcaa taatagctta gatataagta ttgatacttt aaaagaacaa
     3661 acagtgctta tgatggaaaa atgtgaagaa gcaatagaaa agtctgtgac ttgtatgata
     3721 gagaaggatt tagagggtgc aagaaaagta gtagaagatg atgaagaaat aaataaatta
     3781 agagaagaaa taagagataa gagtatagag ctaatagtat taaagcaacc aatggcaagg
     3841 gacttaagat ttatttattc attaggtaat atatctatag agctggaaag aataggagat
     3901 tatgcagcaa atatagctag agaaatgttg aagataggtg gagaggctta tataaaagag
     3961 ctaatagata ttcctaagat ggcaaaagaa tgtaagtcta tgatgtctca gactagagaa
     4021 gctttaatct tatttgatgc aagtatagct tatgatgttg gaactaaaga tgatattgta
     4081 gatggattgt atgaacaagt acaaattgat tgtttaaaaa taatgcatga aaactcaaat
     4141 accatagacc aaggggtaaa acttctactt ataggaagat accttgaaag aattggagac
     4201 catataacaa atgtatgtga gaagataatt tttgcaattg agggtaaaat ggttgagata
     4261 ggataaaaaa ctgctttaaa gcagtttttt tattgtctaa attaagaaag aattgataaa
     4321 aaaatatgat taatgggtaa atttaaaaaa ttgtgatata ctaggaacat attaaatatg
     4381 aggatgcgta ttttatataa ggtgcttttt aggaggtgga actttgaaac ttcaaaagat
     4441 gggtatgagg actataaaaa caggaattag tgtcacttta tgtatgattc ttggtgacta
     4501 tttagtagag aatatgtttt attctctggt agcatgtata atttctgttc aagatacagt
     4561 aaaaggttct ttaaagacgg gaatcaatag agtggaaggt actattttag gtggtataat
     4621 aggattcata tttgccatca ttaaagctgg agacccattt ttatgtggtc taggagtaat
     4681 gtgctcaata tatttatgca atctgtttaa aataaagtca gtagtagttg cctgtgtaac
     4741 ctttctggct atacatctag gtgtaggaaa tagtgaccct gtgtattatt ctttacatag
     4801 ggtgttagat acatctgtgg gtgttttgtt tggagtactt gttaattatt atgttgctag
     4861 accaaattat ctaaatagtg ttatagatga gtttaaaaag atagaagaac tttcaatgtt
     4921 gcttattgaa gataaaattc ttagaaaaga aaatttaaat gtagagaaat ttgaagaaga
     4981 agtagaaaaa ttagaagaaa tatattcaaa acttattgat gagttggatt atagtttgag
     5041 tgaaactaat atagaaaaaa ttgagaatgc cttaaggata tgtagagaaa tacattttca
     5101 tatgcagtct atagagttac ttgaaaataa actttatttg aaagagcata catataaata
     5161 ccttaagaaa acatataatg tggataagct agactggaat atagatgaag aaaaaagccc
     5221 tgtattcaac tatcatctaa tgaaaataat gattgaaata gagttgttga gaaaactaaa
     5281 taaatcatat taataatagt agttaaataa taaataaaaa atagtatctt tgtaaatatt
     5341 aaacatatat aagtttaatt tatggaggta ctatttttta tgaatactag aaatgacaat
     5401 tctaaaatac tagaaatata taaaatgaag ctttttggcg aacttgtaaa agcagtgtgg
     5461 aatgatgaca tagaggatat tgaaaactta cctaataaaa ttttaaatga aaatttaaag
     5521 gataatttaa ataattattt tagtggaaaa tttgataaag atactatggt aaatttaatt
     5581 agggtaacta tgggattgga tgtgacagaa gatacagata aaaatttaaa agagtcacta
     5641 catgaagctg taaatttaga tgaagtcaaa agaccaataa tatctgtaat atcagatgct
     5701 tgcaaatatt gtgatgaaaa taataaggaa gatgagtcat gtaagataag aagtaagcat
     5761 attaattgta atgaggaaga tgtatgtagt gcttgtggtg attgtgtatc aagatgtaag
     5821 ttgggtgcaa tttcagataa aatagaattt ataccaatga taaaattgtt aaaagatata
     5881 aagagccctg tatatgcaat agttgcacca gcttttgtag gacagtttgg gaaagatgta
     5941 agccctggta aattaagaac tgcattaaaa aagataggat ttgaagatat gatagaagtt
     6001 gctttggcag cagatatgct tactgcaaaa gaagcatatg attattatga gcatatgaaa
     6061 aaggacgaag aaggatgctt tataactagt tgttgctgtc ctatttgggt tagtttgata
     6121 caaaatagtt ttcctcaaat attggagaat gtatcaccat ccgtttctcc tatgattgct
     6181 tgtgggagag ctgtaaaaat tttaaatcca gatgctaaag ttgtattcat aggtccttgt
     6241 atggcaaaaa agaaagaggc aatgttagaa gatataaaag atgcagttga ttttgtgctt
     6301 acatttaaag agttgcaaga aatatttgat gcattagagt taaatccagc aataatggat
     6361 gagagtaata gagtagaggc gtccctttca ggtagagttt atgctagaac aggaggtgta
     6421 agtaaagcag ttaagttatc agttagaaga attgacaaaa atataaaatt tgaagaaaag
     6481 gcatttgaag gaacaaaaga gtgcatggac ggtctaaaga aagttctaaa taaagaaata
     6541 gaagctacat ttatagaagg aatggggtgt gtaggaggct gtgtaggagg tccgaagcgt
     6601 attttaagtg tggaagaagg tactaagaat gttgatgaat atagtgaaag tacgaatatg
     6661 gaaactccat ttgataattt aaatgtatta caatttttaa cttctttggg aatcaaaaga
     6721 gtagaatctt taggagaaaa agaagaagaa aaggttaaaa aaatatttag tagagatata
     6781 aaaagtaata agaaagagaa taaatataaa aaataacttt ttaagtctta aacttatgct
     6841 tttataaaag ggagatatgg gggatgaaaa ttaaagataa taaggctgtt tttcatgtat
     6901 ttataaggat atttcttata gctgttttaa ttttaactgg aacattattg gaggaaaaaa
     6961 ttaataatgt tccagttgaa aatataagtt caaaaggtga aaatacactg gaactgcttt
     7021 ctcaaagtaa tactttagga gaaatcatat acaaagcatc tcaagaagaa acaaaaggtc
     7081 caggggctac ttctgaaaaa gtagcataca taacaataga tgatggtcca tcaaaatata
     7141 caaatgcact acttgatatt ttaaaagaaa atgatgtcaa agcgacattt ttcatgctta
     7201 atcagaatat gaaaaaccac aaggaagaag taaggagagt cttggaagaa gaaaactcaa
     7261 taggttttca tagtgtaagt catgatatac ataagttata taaaagccca gaagtaacag
     7321 ttggggaatt taatacatgc aataatactc tacaagaaat aactggtcag agttcaaaat
     7381 taataagatt accatacgga agtaaaccat atatgccaga aggttcatat aataaactta
     7441 tggcaaatga ttatttaatt tgggactgga atttggatac acaggattgg aagtcttcta
     7501 caagtcagat agtaagtaat atattatatt atggaagaaa aagagatgaa ttagtagtat
     7561 taattcatga gaaagagcaa agtttaaatg ctttaaataa tattataaga atcttaaaag
     7621 agagaggata tacaatattg ccaattacag aaaatataac acctaaaaat ttctggcaag
     7681 aaaacttata ataaatttaa atatagtaaa agataaagta aattatttat aaaataaaac
     7741 atataatata aaaaatacga ataagaggta tactgtaagg ataatataaa attaatgaga
     7801 aagcattaaa attaaaataa aataatcttg caattattga cattataaga cagaataact
     7861 gtaaaaacat attttaaaat ataacaacta tataaaagag aatagacata attaagaaaa
     7921 ttcagaaaaa ataaaataaa aataattgac aaagagaata atatttgtat ataataatat
     7981 gtaatattaa agactgagaa gaagaggagt aagtaaatac tactaaaaga gaggaaaatt
     8041 cactggctgt aagattttct aagtataaga tttactgaat gtagctttgg agtttctaaa
     8101 ctgaactata agtaagttta gacggttaga accgttaaat tctttgagag tcaaagttga
     8161 taaaataaca ttaaccaata atttaatgat atgttaatgt attttaagct ttggaattaa
     8221 ggtggtaacg cgagcttttc gtccttttta aagaggatga agagctcttt tttatttcta
     8281 aagatattta aaaaatttat ttataaaata caggaggcag gacaatggaa aatacgaatt
     8341 tatcaaaaac ttataaccca aaagattttg aggctaggct atataaaaaa tggatggatg
     8401 aagggtattt taaatctaaa ccaaatccag ataaaaaacc atttacaata atgatgccac
     8461 caccaaatat aacagggcaa ttgcatatgg gacacgctct tgaccataca cttcaagata
     8521 tattaatcag atggaaacgt atggatggat atgaagcttt ttggcttcca ggaactgacc
     8581 atgcttctat agcaacagaa gttaaagttg ttgaaagaat aaaaaaacaa gaaggcaaga
     8641 caaagtatga aataggtaga gaagaatttt taaagagagc ctgggaatgg aaagatgaat
     8701 ttggaggaaa aatatctaat cagcttaaac aactaggtga ttcttgtgat tgggataaag
     8761 aaagatttac tatggatgaa gggtgtaatg aagcagttat agaatttttt gtaagcctat
     8821 atgaaaaagg tcacatatac agaggaaata gaataataaa ctggtgccca gattgcaaaa
     8881 ctactttatc agatgcagaa gttgaacatg aagaacacga cggaaacttt tatcatataa
     8941 agtacccact aaaagatagt gaagactttt tagaaatagc tacaactaga cctgagacaa
     9001 tgataggaga tactggtata gcagtaaatc cagaagatga tagatataaa catttaatag
     9061 gaaaaacagc aatacttcca ttagtaggaa gagaacttcc aatagttgca gatagttatg
     9121 ttgatttaga gtttggaact ggtgcagtta agatgactcc agcacatgac cctaatgatt
     9181 ttgaagtagg attaagacat aatcttgagc agttaaatac tatgaatgaa gatggaacta
     9241 tgaatgaagt ttgtggaaaa tatgaaggta tggatagatt tgagtgtaga aaagctatcg
     9301 tagcagactt aaaagaacaa ggttacctaa ttaagataaa agagcataat cataatgtag
     9361 gaacttgtta tagatgccat acagtagttg agcctagatt atcagagcaa tggtttgtta
     9421 agatggaaga acttgcaaaa ccagctatag atattcttaa aaaaggagaa ttagaatttg
     9481 ttccagataa atttgataaa acttatttac aatggctaga aaatataaga gattggtgta
     9541 tatcaagaca attatggtgg ggtcatcaaa taccagctta ttattgtcaa gagtgtggag
     9601 aaatagtagt tgctagaaaa atgccagata agtgtcctaa atgtggaagc actcatttta
     9661 aacaagatga agatgcctta gatacttggt tcagttctgc attatggcct ttctctactc
     9721 taggatggcc aaataagact gaagctttag attattatta tccaacaagt gtacttgtta
     9781 caggatacga tataatattc ttctgggtag ttagaatggc atttgcaggt atgttctgta
     9841 tgaatgaaaa gccatttgac catgttttgg ttcatggatt agtaagagat tctcaaggta
     9901 gaaaaatgag taaatcttta ggaaatggta tcgacccatt ggagataatc gagcaatatg
     9961 gagctgatgc cctaagattt acattaacaa ctggaaattc cccaggaaat gatatgagat
    10021 tctatatgga aagagtagaa tttgctagaa actttgcaaa taagttgtgg aatgcatcaa
    10081 gatttgtatt tatgaatatt gatgaagata taattaaaaa catgactaga gaaagtgtta
    10141 aagaggactt aactctagct gataaatgga taatatcaag agcaaataat attgtaaaag
    10201 aagcaactaa taacatggat aagtttgatt taggaatagc acttcaaaag atatacgatt
    10261 ttacttggtc agaatactgt gactggtata ttgaaatggt taaacctaga ttatatggag
    10321 aagatgcaaa tgctaaatct gcagcattat atacattaac ttatgttctt gaaaaaatat
    10381 taaaattatt acatccatac atgccattta taacagagga aatatatact catcttccta
    10441 ctgttgaagg atgtataata gtatctgaat ggccaaaata taatgaagaa gataacatgg
    10501 ctgaagaaga agatatgatg aacttattga tggaaggtat aagaagtata agaaatgtga
    10561 gagcagaaat gaatgtacca ccttctaaga aagctaaatt gataataatc ccaagtgaag
    10621 aaaaaataga agctattgag cttggtaaag actattttat aactttagca tctgcttcaa
    10681 atgtagagat agcaaaagat aaatctaatg ttccagaaga tgcagttgga gtagttattg
    10741 atggtgttga aatatttata cctcttaatg aattagttga ttttgaaaaa gaaattgaga
    10801 gattatctaa agaaaagaaa aagttagaag gcgaaataaa gagagttaat ggaaagcttg
    10861 caaatcaagg tttcttagca aaagctcctg aaagtttaat tgaagaagaa aaagcaaaaa
    10921 aagaaaaatt tgaagagatg attaaatctg ttgaggaaag attaacaaat ttagaatcta
    10981 aaataaaata aatataagaa ttagtaaaaa catacaaaaa gtatatattc tatacttttt
    11041 gtatgttttt ctttatatat atacaaatat gatgttataa ttctttacag atgtgttata
    11101 tttttatttt atgttgtgaa tatatgaatt ttatgtctta aaatttataa gcaa
//
LOCUS       DAYAOO010000116        10788 bp    DNA     linear   BCT 12-OCT-2024
DEFINITION  TPA_asm: Clostridioides difficile isolate ST8-SSI-h139-18
            SAMN40601845-rid21577343.denovo.119, whole genome shotgun sequence.
ACCESSION   DAYAOO010000116 DAYAOO010000000
VERSION     DAYAOO010000116.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN40601845
            Sequence Read Archive: SRR28438827
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 10788)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10788)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-MAY-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-MAY-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002157583.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002157583.1
            Genome Coverage       :: 163x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/11/2024 16:19:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 4,038
            CDSs (total)                      :: 3,963
            Genes (coding)                    :: 3,930
            CDSs (with protein)               :: 3,930
            Genes (RNA)                       :: 75
            rRNAs                             :: 6, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 60
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 33
            CDSs (without protein)            :: 33
            Pseudo Genes (ambiguous residues) :: 0 of 33
            Pseudo Genes (frameshifted)       :: 7 of 33
            Pseudo Genes (incomplete)         :: 25 of 33
            Pseudo Genes (internal stop)      :: 11 of 33
            Pseudo Genes (multiple problems)  :: 8 of 33
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10788
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN40601845-rid21577343.denovo.119"
                     /isolate="ST8-SSI-h139-18"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Denmark"
                     /collection_date="2018"
                     /collected_by="Statens Serum Institute"
     gene            88..1407
                     /gene="dnaA"
                     /locus_tag="ACGI5H_003476"
     CDS             88..1407
                     /gene="dnaA"
                     /locus_tag="ACGI5H_003476"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420483.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003688 - DNA replication origin binding
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006270 - DNA replication initiation
                     [Evidence IEA];
                     GO_process: GO:0006275 - regulation of DNA replication
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="chromosomal replication initiator protein DnaA"
                     /protein_id="HFG9699163.1"
                     /translation="MDIVSLWDKTLQLIKGDLTSVSFNTFFKNIVPLKIHLNDLILLA
                     PSDFNKDILENRYLHLIEDAISQLSLKKYNIKFVLSEKEVADLNSDSTDLNYRVLYPN
                     LNPKYTFDTFVIGNSNRFAHAACVAVAESPAKAYNPLFLYGGVGLGKTHLMHAIGHHI
                     VSQKKDSKVVYVSSEKFTNELINSIKDDKNEEFRNKYRNVDVLLIDDIQFIAGKERTQ
                     EEFFHTFNTLHEANKQIIISSDRPPKDIPTLEDRLRSRFEMGLITDIQAPDFETRIAI
                     LRKKAQLERIDVPNEVMSYIAKNIKSNIRELEGALTRVVAYSSLSNRVISFDLATEAL
                     KDIITTSKNEEINVLRIKEKVSSVFNLKMEDFNSKKRTRSIAYPRQIAMYLTRELTDL
                     SLPKIGEEFGGRDHTTVIHAHDKVSKDIEESEEIKTKIDKIISDLKG"
     gene            1649..2755
                     /gene="dnaN"
                     /locus_tag="ACGI5H_003477"
     CDS             1649..2755
                     /gene="dnaN"
                     /locus_tag="ACGI5H_003477"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420481.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009360 - DNA polymerase III complex
                     [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003887 - DNA-directed DNA polymerase
                     activity [Evidence IEA];
                     GO_process: GO:0006260 - DNA replication [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit beta"
                     /protein_id="HFG9699164.1"
                     /translation="MKIICNQKILANRIGIAQKAINGKTTIELLKGILISTEEGQLKL
                     TGYDAEIGIETYVQAEIIEKGDVVVDARLFGDIIRKLPDSFVEIETDSENNIYINCVN
                     SRFKIKGYAAKEFPKLPELNEEDLYSIPQEILKNMIKQTVFAISQDQTKPVLMGELLE
                     IVDRNLNLVAIDGYRLAVKSCSVDSLTENIKVIIPGKTLIDVNSLLSGEDNVKVGFNE
                     KNAIFIINDTKIITRLLEGDFIDYKKLLPREHNSRVKLNTKELLNSIERASLLSQSEK
                     NNLIKLSIRDKVMAITSNTEKGNVYEEVEIDLDGDYLDIAFNSRYFIEGLKNIDNEEI
                     FIEFTTNVNPCIIKPTDDVNYIYLLLPVRISSNI"
     gene            2892..3098
                     /gene="yaaA"
                     /locus_tag="ACGI5H_003478"
     CDS             2892..3098
                     /gene="yaaA"
                     /locus_tag="ACGI5H_003478"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420479.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="S4 domain-containing protein YaaA"
                     /protein_id="HFG9699165.1"
                     /translation="MTEITIESEYIKLDQFLKLAEIASTGGHAKFLIQEGLVTVNDEI
                     ELRRGKKIKSGDIVEIEGTKIKVL"
     gene            3116..4231
                     /gene="recF"
                     /locus_tag="ACGI5H_003479"
     CDS             3116..4231
                     /gene="recF"
                     /locus_tag="ACGI5H_003479"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420477.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003697 - single-stranded DNA binding
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA replication/repair protein RecF"
                     /protein_id="HFG9699166.1"
                     /translation="MKLKSLQLVNFRNYKKLHLEFNGKVNLLVGKNGQGKTNIVESIY
                     MLSFGKSFRTNKDKEMVRFNSENLYIGGSFSKYNKYSLIELIIGKDKKGIRINKVPLQ
                     KIQELLGNLNVVIFSPEDLRLVKEGPKERRAFIDKEISQIIPKYYKYLTNYNKTLSQR
                     SRVLKNIHVDEALLDVYDDTLAKYGSYIYILRRDFIKKIANISENMHMNLTNGVERLS
                     IRYKNQINITDEDTIDTVYNKFLAKLSSNRPNDIESKTTRYGIHKDDLNIFINDLDAR
                     LFGSQGQQRTASISLKLSEIELIKNEVEEYPVLILDDVFSELDEARQKLLVNNLSNVQ
                     MFITSAEVSHKKIFDEKNVTIFNIENGDVISIENGGN"
     gene            4232..6133
                     /gene="gyrB"
                     /locus_tag="ACGI5H_003480"
     CDS             4232..6133
                     /gene="gyrB"
                     /locus_tag="ACGI5H_003480"
                     /EC_number="5.6.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434229.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005694 - chromosome [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003918 - DNA topoisomerase type II
                     (double strand cut, ATP-hydrolyzing) activity [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006265 - DNA topological change [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase (ATP-hydrolyzing) subunit B"
                     /protein_id="HFG9699167.1"
                     /translation="MKQEYGASQIQVLEGLEAVRKRPGMYIGSTSPRGLHHLVYEVVD
                     NSIDEALQGYCSDIYVSINEDGSVLVKDNGRGIPVEIHPKTGKSTLETVLTNLHAGGK
                     FGGGGYKVSGGLHGVGVSVVNALSKWMVAEVYLNGKIYKQTYEKGLPTSKLEVVGESQ
                     DKGTMIQFMPDETIFDEIEFKYETLEYRLRELSFLNKGIKIVFEDKREGQEKRKEFHY
                     TGGLVEYIKYLNKSRTGIHDDIVYIDKKVDDCFVELAMQYTDGYTENIYSFANNINTH
                     EGGSHLSGFKAALTKTVNDYAKRNKFLKENDVNLLGEDIREGLTAVVSVKLPEPQFEG
                     QTKTKLGNSFMRGIVDSVTVDELGSFLEENPSTARIIVDKALRAQRAREAAKKARELT
                     RRKSVLESTSLPGKLADCAEKDPSKSEIFLVEGDSAGGSAKQGRDRNSQAILPLRGKI
                     LNVEKSRLDRILSSDEIKNMITAYGCGIGEDFDIDKARYHKIIIMTDADVDGAHIRTL
                     LLTFFFRYMRPLIDEGYVYAAQPPLYKVTKQKKEHYVYSDKELNILLDEIGRNGVELQ
                     RYKGLGEMNAEQLWETTMNPETRTLLQVTVEDAAIADEVFSMLMGDKVAPRKEFIEEN
                     ARFVRNLDI"
     gene            6153..8579
                     /gene="gyrA"
                     /locus_tag="ACGI5H_003481"
     CDS             6153..8579
                     /gene="gyrA"
                     /locus_tag="ACGI5H_003481"
                     /EC_number="5.6.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422332.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003916 - DNA topoisomerase activity
                     [Evidence IEA];
                     GO_function: GO:0003918 - DNA topoisomerase type II
                     (double strand cut, ATP-hydrolyzing) activity [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006259 - DNA metabolic process [Evidence
                     IEA];
                     GO_process: GO:0006265 - DNA topological change [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA gyrase subunit A"
                     /protein_id="HFG9699168.1"
                     /translation="MEENNKILPIEIAEEMKKSYIDYSMSVIAGRALPDVRDGLKPVH
                     RRILYSMSELNLTPDKPYRKSARIVGDVLGKYHPHGDTAVYYAMVRMAQDFSTRALLV
                     DGHGNFGSVDGDSPAAMRYTEAKMSKLSLELLRDIEKETVDFKPNFDESLKEPSVLPA
                     RYPNLLVNGSNGIAVGMATSIPPHNLAEVIDATVYLIDNPECSVDDLIKFVQGPDFPT
                     AAIIMGKESIAEAYRTGRGKVKVRSRAFIEELPKGKQQIIVTEIPYQVNKAKLVERIA
                     ELVKEKRIEGISDLRDESNRNGMRIVIELKRDANANIVLNNLYKHSQMEDTFSIIMLA
                     LVDGQPRVLNLKQILYHYIKHQEDVVTRRTKFELNKAEARAHILEGLKIALDNIDAVI
                     SLIRASKTGQEAKLGLIEKFKLTEIQAQAILDMRLQRLTGLERDKIEAEYEDLIKKIN
                     RLKEILADERLLLNVIKDEITIIKENYSDERRTEIRHAEGEIDMRDLISDEEIAITLT
                     HFGYIKRLPSDTYKSQKRGGRGISALTTREEDFVRHLVTTTTHSRLLFFTNKGRVFKL
                     NAYEIPEGKRQAKGTAIVNLLQLSADEKIATLIPIDGNDENEYLLLATKKGIVKKTKR
                     EEFKNINKSGLIAIGLRDDDELIGVELTDGKQEVLLVTKEGMSIRFDENDIRYMGRTA
                     MGVKGITLSKEDFVVSMNLCSKGTDVLVVSKNGFGKRTNIEEYRSQIRAGKGIKTYNI
                     SEKTGTIVGADMVNEDDEIMIINSDGVLIRIRVNEISLFGRVTSGVKLMKTNDEVNVV
                     SIAKINIEEE"
     gene            8648..8944
                     /locus_tag="ACGI5H_003482"
     CDS             8648..8944
                     /locus_tag="ACGI5H_003482"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420471.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YtxH domain-containing protein"
                     /protein_id="HFG9699169.1"
                     /translation="MCNKRSCKKGGFLLLGAILGFIFGMFFAPKKGSELRKETKEKFN
                     DVKENPKEVLHETFNDVKERIINLVDDDNNEEDIKISEEDIVISKSFDDEGDVN"
     gene            8944..9204
                     /locus_tag="ACGI5H_003483"
     CDS             8944..9204
                     /locus_tag="ACGI5H_003483"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF948 domain-containing protein"
                     /protein_id="HFG9699170.1"
                     /translation="MNAWGWQIGAVLVGSSALIVAIYLAKTLNSINKVVEKAYKIVDY
                     NERHIQDIVENASSISKGIDDIVYVINKILSIGNIFKIIKRK"
     gene            9216..9533
                     /locus_tag="ACGI5H_003484"
     CDS             9216..9533
                     /locus_tag="ACGI5H_003484"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894128.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0043856 - anti-sigma factor antagonist
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="STAS domain-containing protein"
                     /protein_id="HFG9699171.1"
                     /translation="MSMNIDSNLDSQNKFWNVCLDGELDVSTADKLKEHLHALIEKNM
                     LDVKINLKDLDYIDSTGLGAMIGVLKKLKINEKEIYIVNPKSNVRKIFTITGLDKIFK
                     VEG"
     gene            9537..9944
                     /locus_tag="ACGI5H_003485"
     CDS             9537..9944
                     /locus_tag="ACGI5H_003485"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892343.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HFG9699172.1"
                     /translation="MACETIKMEITTNPDYVSIIRLTASGIANKMGFPIDDIEDIKVA
                     VSEACTNAIKHSKDDVFNIVFNILDNAINIEIQDNGKGYDVSSISTPDLENPKESGLG
                     LFIIKTLMDDVDIESEHNQGTKIKMTKYLGVDI"
     gene            9944..10717
                     /locus_tag="ACGI5H_003486"
     CDS             9944..10717
                     /locus_tag="ACGI5H_003486"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420464.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_function: GO:0016987 - sigma factor activity [Evidence
                     IEA];
                     GO_process: GO:0006352 - DNA-templated transcription
                     initiation [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="SigB/SigF/SigG family RNA polymerase sigma
                     factor"
                     /protein_id="HFG9699173.1"
                     /translation="MKNVANATHYLNMDTKELFNLYNKNKNVDIRNILIERHLYLARL
                     LAKKYINKGVDFEDIYQVASLALIYAIDRYDVEKGFEFSSFATPTIVGEIKKYFRDKV
                     WTLRVPRRIQELSKKISDAKIKLEQENKKHPKVKDIADYIGVSEEDVLEAMEASYGYQ
                     PMSLDSSSNDDSEDKDITLIDKIGKEEGNFGSIEYEDFINKFIETLNELEVKIFKDRF
                     FFDKTQSSIAKELGISQMTVSRLEKKVVEKLKKEYEKNL"
BASE COUNT         4401 a         1115 c         1992 g         3280 t
ORIGIN      
        1 gttattctgt aaaatttata tatatttttg cttttctgtt aataactttg tggaaaatat
       61 taattattct gttcggaggt ttatattatg gatatagttt ctttatggga caaaacccta
      121 caattaataa aaggtgactt aacttcagta agttttaata ccttttttaa aaacatcgta
      181 ccattaaaaa tacatcttaa tgatttaatc ttactggctc ctagtgattt taataaagat
      241 atcttagaga atagatattt acatttaatt gaagatgcta ttagtcaact gtcattaaaa
      301 aaatataata ttaaatttgt attgagcgaa aaagaggttg ctgatttaaa ttctgatagc
      361 acagatttaa attatagagt tctttacccc aatctaaatc caaaatacac atttgataca
      421 ttcgttattg gtaatagtaa tagatttgca catgctgcat gcgttgcagt tgcagaatct
      481 ccagctaaag cttataaccc actttttttg tatggaggag ttggattagg taagactcac
      541 ctaatgcatg ctataggtca tcatattgtt agtcaaaaaa aagactcaaa agtagtttac
      601 gtttcttcag aaaaatttac taatgaactt ataaactcta taaaagacga taaaaacgaa
      661 gaatttagga ataaatatag aaacgtagat gtattactaa tcgacgatat tcaatttata
      721 gcaggaaaag aaagaactca agaagagttt ttccatacat tcaatactct tcatgaagca
      781 aacaaacaaa taattatatc tagtgataga ccgccaaaag acatacctac actagaagat
      841 aggctaagat cgagatttga aatgggactt ataactgata ttcaagcacc tgactttgag
      901 acaagaattg ctatacttag aaaaaaggct caactagaac gtatagatgt gccaaatgag
      961 gttatgtcat atatagcaaa aaatattaag tcaaacataa gggaactaga aggtgcatta
     1021 actagagtgg ttgcttattc ttctcttagc aatagggtaa tatcttttga tcttgctaca
     1081 gaagctttaa aagatattat aacaacttct aaaaatgaag aaataaatgt tctcagaata
     1141 aaagaaaaag tatcttctgt attcaattta aagatggaag attttaattc taaaaaaaga
     1201 acacgttcaa tagcttatcc aagacagata gctatgtatt taacgcgcga gcttactgat
     1261 ttatcccttc ctaaaatagg tgaagagttt gggggtagag accatacaac agtaattcat
     1321 gctcatgaca aagtatctaa ggatatagaa gaaagtgaag aaattaagac taaaatagac
     1381 aaaattatat cagatttgaa gggataattt atacacaatt gtatgtttat atctcttgaa
     1441 taacctgtta atactttttt tgaacaaaaa ttattaacaa attatcaagt ctaaaataac
     1501 aaagatatta acatcttata cacatgttaa tatctttgta tttataatgt tatacatact
     1561 tattaacatt atcaacaaca cctactacta ttactactat gattttaact tatttttata
     1621 tataaaaagc cagaggaggt tatccacatt gaaaataatt tgtaatcaaa aaatcctagc
     1681 aaatagaatt ggaattgctc aaaaagctat taatggaaaa acaacaatag aattattaaa
     1741 aggtatactt atatctacag aagaaggtca attaaaactt actggatatg atgctgaaat
     1801 aggaatagaa acttatgtac aagcagaaat catagaaaaa ggtgatgttg ttgtagatgc
     1861 aaggctattt ggagatataa ttagaaaatt accagattcc tttgttgaga tagaaactga
     1921 ttcagaaaat aatatttaca taaattgtgt aaattcaaga tttaaaatta aaggttatgc
     1981 agcaaaagaa tttcctaaat taccagaatt aaatgaagaa gatttatata gcatacctca
     2041 agaaatccta aaaaatatga ttaaacaaac tgtatttgct atctcacagg accaaacaaa
     2101 acctgtttta atgggagaac ttttagaaat tgtagataga aacttaaatt tagtagcaat
     2161 tgatggatat agattagctg taaaaagttg ttcggttgat agtttaactg aaaatataaa
     2221 agtcataatt cctggaaaga cacttataga tgtaaatagt ttgctttctg gagaggataa
     2281 tgttaaagtt ggatttaatg aaaaaaatgc tatttttata attaatgata cgaaaattat
     2341 tacaagattg cttgaaggag attttattga ttataaaaaa ttattgccaa gagaacataa
     2401 cagcagagtt aaattaaata ctaaggaact tttaaatagt atagagagag cgtctttatt
     2461 gtctcaatca gaaaaaaata atcttataaa gttatctata agagataaag taatggcaat
     2521 tacttctaat acagaaaaag gaaatgtgta tgaagaagtt gaaatagatt tagatggaga
     2581 ttacctagat atagctttca attctagata ttttatcgaa ggtttgaaaa atatagataa
     2641 tgaggaaata tttatagaat ttactacaaa tgtaaatcct tgtataatta aaccaacaga
     2701 tgatgttaat tatatttact tactgcttcc agtaagaata tcatcaaata tatagcagac
     2761 atgaaggagt tgtcttttgt agaaaatttt tctaatctta gacaactcct tttataagca
     2821 tatttatggt ataatatact tttagtgtat caataggaat ttgtttaaaa tagtgacaag
     2881 gaggaactat tatgactgaa ataactatag aatcagaata tataaagttg gatcaatttc
     2941 ttaaattagc agagattgca tcaacaggag gtcatgcaaa atttttaatt caagaaggtt
     3001 tagtgacagt aaatgatgaa atagaattaa gaagaggaaa aaagataaaa tcaggagata
     3061 tagttgaaat agaaggaact aaaataaaag tattgtaaaa aaaggagaac tttttgtgaa
     3121 acttaaaagt ttgcaacttg ttaattttag aaattataaa aagttgcatc tggaatttaa
     3181 tgggaaagta aatctacttg ttggtaaaaa tggtcaagga aagacaaata tagtagaatc
     3241 tatttatatg ctttcttttg gaaaatcatt taggactaac aaagataaag aaatggttag
     3301 atttaatagt gaaaacttat atattggagg aagtttttca aaatataata aatatagtct
     3361 aatagagcta attattggaa aagataaaaa agggataaga ataaataaag ttcctttaca
     3421 aaagatacaa gaactacttg gcaacttaaa tgttgttata ttttctcctg aggatttaag
     3481 gttggttaaa gagggtccta aagaaagaag ggcatttata gacaaagaga ttagtcagat
     3541 tatacctaaa tattataaat atcttaccaa ttataataaa acactttctc aaaggagtag
     3601 ggtgcttaaa aatatacatg ttgatgaagc tttattagat gtatatgatg atacgttagc
     3661 aaagtatgga agttatattt atattttgcg tagagacttt ataaaaaaga tagctaatat
     3721 atctgaaaat atgcatatga atttgactaa tggagttgaa agattatcaa ttcgatataa
     3781 aaatcaaata aatataactg atgaagatac tatagataca gtatataata aatttttagc
     3841 caagttgtca tcgaatagac ctaatgatat agaatctaag actaccagat atggtataca
     3901 caaagatgac ttaaatatat tcataaatga tttagatgca agactttttg gttcacaagg
     3961 tcaacaaaga actgcttcaa tatcattaaa gttatcagag atagaattaa taaaaaatga
     4021 agttgaagaa tatccagtat taattttaga tgatgttttt agtgagttag atgaagcaag
     4081 acaaaaactt ttagtaaata atttaagcaa tgttcaaatg tttataacaa gtgctgaagt
     4141 ttcacataaa aaaatatttg atgaaaaaaa tgttacaata tttaatattg aaaatggcga
     4201 tgttattagc atagagaatg gaggaaatta aatgaaacaa gaatacggtg caagtcagat
     4261 acaagtatta gagggattag aagccgttag aaaaagacca ggtatgtata ttggtagtac
     4321 aagccctaga ggtttacatc acttagttta tgaagttgta gataatagta tagatgaggc
     4381 tttacaagga tattgttcag acatatatgt atctattaat gaagatggca gtgttttagt
     4441 aaaagataac ggaagaggta tacctgttga aatacatcct aaaactggta aatcaacttt
     4501 agaaacagta ttaactaatc ttcatgcagg aggaaagttt ggaggcggag gatataaagt
     4561 atctggaggt cttcatggag ttggtgtttc tgtagttaat gcattgtcaa aatggatggt
     4621 agcagaggtt tatttaaacg gaaagatata taagcagaca tatgagaaag gattgccaac
     4681 atctaagctt gaagtagttg gagaatctca agataaagga acaatgattc aatttatgcc
     4741 agatgagaca atatttgatg aaatagagtt taaatatgaa acattggagt ataggcttag
     4801 agaactttct ttcttgaata aaggaataaa aatagtattt gaagataaaa gagaaggaca
     4861 agaaaaaaga aaagaatttc actatacagg tggtttggta gaatatatta agtatttaaa
     4921 taaatctaga actggtatac atgatgacat agtttatata gataaaaagg ttgatgattg
     4981 ttttgttgaa ctagctatgc aatatacaga tggttataca gagaacatat attcttttgc
     5041 aaacaatata aatacacatg aaggtggttc tcatttaagt ggatttaaag cagctcttac
     5101 taaaactgta aatgattatg ctaagagaaa taaattttta aaggaaaatg atgttaacct
     5161 acttggtgaa gacataagag aaggtcttac agcagtagta tcagttaaat taccagaacc
     5221 tcaatttgaa ggtcaaacta aaacaaagct aggtaatagc tttatgagag gtatagttga
     5281 tagtgtaaca gttgatgaac tggggtcttt cctagaagaa aacccatcaa cagcaagaat
     5341 catagttgat aaagctttaa gagcacaaag agctagagaa gctgcaaaaa aagcaagaga
     5401 attaacaagg agaaaaagtg tattagaaag tacatcttta cctggaaaac ttgcagattg
     5461 tgcagaaaaa gatccatcta aaagtgaaat attcttagtc gaaggggatt cagcgggagg
     5521 ttcagctaaa caaggtagag atagaaatag tcaagctata cttccattaa gagggaaaat
     5581 acttaatgtt gagaaatcaa gactagatag gatactatct tcagatgaaa taaaaaatat
     5641 gataacagct tatggttgtg gtattggaga agattttgat atagataagg ctaggtatca
     5701 taaaattata attatgaccg atgctgatgt agacggagcc catataagaa ctttattatt
     5761 aacattcttc tttagatata tgagacctct tatagatgag gggtatgttt atgcagcaca
     5821 gccaccttta tataaagtga caaagcaaaa gaaggaacat tatgtttact cagataaaga
     5881 gttaaatatc ttactagatg aaattggaag aaatggtgtt gaacttcaaa ggtacaaagg
     5941 tcttggagag atgaatgcag agcaattatg ggaaacaact atgaatcctg agacaagaac
     6001 tttattacaa gttactgtag aagatgctgc aattgcagat gaagtatttt caatgcttat
     6061 gggtgataag gttgctccaa gaaaagaatt tatagaagaa aatgcaagat ttgttagaaa
     6121 cttagatata tagagagagg ggattagtat acatggaaga aaataacaaa atactcccta
     6181 ttgaaatagc ggaagaaatg aaaaaatcgt atattgatta ttcaatgagt gttatagctg
     6241 gacgtgctct tcctgatgtt agagatggtt taaagccagt tcatagaaga atattatatt
     6301 caatgagtga gttaaattta actccagata aaccatacag gaagtcagct cgtattgttg
     6361 gggacgtttt aggtaagtac catcctcatg gagatactgc tgtttattat gctatggtaa
     6421 gaatggcaca agatttttca actagagcac ttttagtaga tggtcatggt aactttggtt
     6481 ctgttgatgg ggattcacca gctgctatgc gttatacaga agctaaaatg agtaaattat
     6541 cattagaact actgagagat attgaaaagg aaactgtaga ctttaaacca aactttgatg
     6601 agtcgttaaa agagccttca gtattgccag ctagatatcc taatttatta gtaaatggct
     6661 caaatggtat agctgttggt atggcaactt caatacctcc acataattta gcagaagtaa
     6721 ttgatgcaac tgtatatttg atagataatc cagagtgtag tgtagatgat ttaataaaat
     6781 ttgttcaagg accagatttc cctacagctg caattataat gggaaaagaa agtatagcag
     6841 aagcatacag aactggaaga ggaaaagtta aagttaggtc tagagctttt atagaagagc
     6901 taccaaaagg aaaacagcaa ataatagtta cagaaatacc ttatcaagta aataaggcta
     6961 aactggttga aagaatagca gagttagtta aagaaaagag aatagaaggt atatcagacc
     7021 taagagacga aagtaataga aatggtatga gaattgttat agaattaaag agggatgcta
     7081 atgctaatat agtattaaat aatttgtata aacattctca aatggaagat acttttagta
     7141 taataatgct tgcacttgta gatggtcagc caagagtttt aaatcttaaa caaatattat
     7201 atcattatat taaacatcaa gaagatgttg ttacaagaag aactaaattt gaactaaata
     7261 aagctgaagc aagagcacat attttagaag gattaaagat tgctttagat aatatagatg
     7321 ctgttataag cttgataaga gcttcaaaga ctgggcaaga agctaagcta ggtttaatag
     7381 aaaaattcaa attaactgaa atccaagcac aagctatatt agatatgaga cttcaaagac
     7441 ttacaggttt agaaagagat aagatagaag ctgaatatga agatttaatc aagaagataa
     7501 atagattaaa agagatttta gctgatgaaa gattactttt aaatgtaata aaggatgaaa
     7561 ttacaataat aaaagaaaat tactctgatg agagaagaac agaaataaga catgctgaag
     7621 gcgaaataga tatgagagat cttataagtg atgaagaaat agcaataact cttactcact
     7681 ttggatatat aaaaaggctt ccatctgata cttataagag tcaaaaaagg ggtggaagag
     7741 gtatttcagc acttacaact agagaagaag attttgtaag gcacttggta actacaacta
     7801 ctcatagtag actattattc tttacaaata aaggtagagt atttaaatta aatgcatatg
     7861 aaataccaga aggtaagaga caggctaaag gtactgctat agtgaattta cttcaattgt
     7921 cagcagatga gaaaattgct actctaatac ctattgatgg taatgatgaa aatgaatatt
     7981 tattacttgc aacgaaaaaa ggtattgtta aaaagactaa gagagaagag ttcaaaaata
     8041 taaataaatc tggtcttatt gcaataggtt taagagatga tgatgagctt attggagtag
     8101 aacttacaga tggaaaacaa gaagtacttt tagtaactaa agaaggtatg tctataagat
     8161 ttgatgaaaa tgatataaga tatatgggta gaacagcaat gggtgtaaaa ggtataactt
     8221 taagtaaaga agattttgtt gtgtctatga acctttgcag taaaggtaca gatgtgttag
     8281 ttgtaagtaa gaatggtttt ggaaagagaa caaatataga agagtataga agtcaaataa
     8341 gagctggtaa aggaattaaa acttataata tatctgaaaa aactggtaca attgtaggtg
     8401 cagatatggt caacgaagat gatgagataa tgattataaa ttctgatgga gttcttatta
     8461 gaataagagt caatgaaata tcactgtttg gaagagttac aagtggtgtt aaattaatga
     8521 agacgaatga tgaagtcaat gtagtttcga ttgccaaaat aaatattgaa gaagaatagg
     8581 ataaatatcc tattcttttt gtataatgta gttagataaa aatttaaaat tgaaaggagt
     8641 aattgttatg tgcaataaaa gaagttgtaa aaaaggtgga tttttattat taggagctat
     8701 tttagggttt atatttggta tgttttttgc acctaaaaaa ggttctgaac taagaaaaga
     8761 aacaaaagag aagtttaatg atgtcaaaga aaatccaaaa gaagttctac atgaaacatt
     8821 taatgatgtt aaagagagaa taataaattt agtggatgat gataataatg aagaagatat
     8881 aaagatttca gaagaagata tagtaataag taaaagcttt gatgatgagg gagatgttaa
     8941 ctaatgaatg catgggggtg gcaaattgga gcagtgttag taggaagctc tgctcttata
     9001 gtagcaattt atttagctaa aactctaaac agcataaata aggttgttga aaaggcatat
     9061 aagattgtag attataatga aagacatata caagatattg ttgaaaatgc atcatcaata
     9121 tcaaagggaa tagatgatat agtttatgta attaataaaa tattgagtat aggaaatata
     9181 tttaaaatta ttaaaaggaa ataggaggtt tttacatgtc tatgaatatt gattcaaatt
     9241 tagattcaca aaataaattt tggaatgttt gtcttgatgg agaacttgat gtttctacag
     9301 cagataaact aaaggaacat ttacatgctt taatagaaaa aaatatgtta gatgtaaaga
     9361 ttaatcttaa agatttagat tatatagact caacaggctt aggagctatg ataggtgtat
     9421 taaaaaaatt aaaaataaat gaaaaagaga tatacatagt aaatcctaag agtaacgtaa
     9481 gaaagatttt tactataaca ggtctagata aaatatttaa agtggaggga taaactttgg
     9541 cttgtgagac tataaagatg gaaattacta caaatccaga ttatgttagt ataataagat
     9601 taacagcatc tggaattgcc aataagatgg gttttccaat agatgatata gaagatataa
     9661 aggtagcagt atctgaagca tgtacaaatg caataaaaca cagtaaagat gatgtgttta
     9721 atatagtatt taatatttta gataatgcaa ttaatataga aattcaagat aatggaaaag
     9781 gatatgatgt tagctcaata agtacaccag atttagagaa tccaaaagag agtggtcttg
     9841 gattgtttat aattaaaact ttaatggatg atgtagatat tgaatcagaa cataatcaag
     9901 ggacaaaaat aaaaatgact aaatatttag gagttgatat ttaatgaaaa atgtagctaa
     9961 tgctacacat tacctaaata tggatacaaa agagctattt aatttatata ataaaaataa
    10021 aaatgtagac attagaaata ttcttattga aagacatctg tatttagcaa gattgttagc
    10081 taagaagtat ataaacaaag gtgttgattt tgaagatata tatcaagttg cttcattggc
    10141 attaatttat gctattgata gatatgatgt tgagaaagga tttgagttct ccagctttgc
    10201 aacaccaact atagtaggag aaataaaaaa gtattttaga gataaggtat ggacacttag
    10261 agtcccaaga agaatacagg aattaagcaa aaagataagt gatgcgaaga ttaaattaga
    10321 acaagaaaat aagaagcatc caaaggtaaa agatatagct gattatatag gcgttagtga
    10381 agaagatgtt ttagaggcta tggaggcttc ttatggatat caaccaatgt ctttggattc
    10441 atcaagtaat gatgattcag aggataaaga tataactctt attgataaga ttggaaaaga
    10501 agaaggtaac tttggaagta tagagtatga agattttatt aataagttta ttgaaacttt
    10561 aaatgaatta gaagttaaaa tttttaaaga tagatttttc tttgataaaa cacaatctag
    10621 tatagctaaa gaactaggga tatcacagat gactgtttct agactagaga aaaaggtagt
    10681 agagaagctg aaaaaagaat atgaaaaaaa tttataaaaa aatataaaaa aagtattgac
    10741 ctactgtttt aaagatggta tagtattact tgtccttgaa aaaaggaa
//
LOCUS       DAYAOO010000117        10680 bp    DNA     linear   BCT 12-OCT-2024
DEFINITION  TPA_asm: Clostridioides difficile isolate ST8-SSI-h139-18
            SAMN40601845-rid21577343.denovo.120, whole genome shotgun sequence.
ACCESSION   DAYAOO010000117 DAYAOO010000000
VERSION     DAYAOO010000117.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN40601845
            Sequence Read Archive: SRR28438827
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 10680)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10680)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-MAY-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-MAY-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002157583.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002157583.1
            Genome Coverage       :: 163x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/11/2024 16:19:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 4,038
            CDSs (total)                      :: 3,963
            Genes (coding)                    :: 3,930
            CDSs (with protein)               :: 3,930
            Genes (RNA)                       :: 75
            rRNAs                             :: 6, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 60
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 33
            CDSs (without protein)            :: 33
            Pseudo Genes (ambiguous residues) :: 0 of 33
            Pseudo Genes (frameshifted)       :: 7 of 33
            Pseudo Genes (incomplete)         :: 25 of 33
            Pseudo Genes (internal stop)      :: 11 of 33
            Pseudo Genes (multiple problems)  :: 8 of 33
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10680
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN40601845-rid21577343.denovo.120"
                     /isolate="ST8-SSI-h139-18"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Denmark"
                     /collection_date="2018"
                     /collected_by="Statens Serum Institute"
     gene            <1..321
                     /locus_tag="ACGI5H_003487"
     CDS             <1..321
                     /locus_tag="ACGI5H_003487"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893427.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="M20/M25/M40 family metallo-hydrolase"
                     /protein_id="HFG9699174.1"
                     /translation="VEKADCYTGNTIESERFFPGWLYDEEDEFVQAAYKGLKEAGIDS
                     EITQYSFCTNGSHYAGEAGIKTIGFGPSKENLAHTIDEYIEQEQLFIGTEGYYGILKS
                     VYGK"
     gene            454..1824
                     /gene="hydA"
                     /locus_tag="ACGI5H_003488"
     CDS             454..1824
                     /gene="hydA"
                     /locus_tag="ACGI5H_003488"
                     /EC_number="3.5.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424374.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0004157 - dihydropyrimidinase activity
                     [Evidence IEA];
                     GO_process: GO:0008152 - metabolic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="dihydropyrimidinase"
                     /protein_id="HFG9699175.1"
                     /translation="MGTILRGGTIITSDKTYISDLRIEDEKIVEIGNNLEINGDKVID
                     ATGKIVIPGGIDTHTHFDMNAGSITTADNFETGTRAAIAGGTTTILDFAEANEGENLL
                     QGVEAYHKKASGNCYCDYGFHMTITCLNKDTFNHMEKLISDGIVSFKMYMAYDGMKVD
                     DGTIYRVLKKARDLGCIVGFHCENGDLLDVLIEENIQNGNLEPKYHPLTRPNIVEKES
                     VSRLADITKLSNSKSYVVHLSCRESLETVKIAREKNIDMIVETCPQYLLLEDNLYNKD
                     KFEGAKYVMSPPLRKKEDINYLWEGLSSGDIQTVGTDHCSFNFKGQKDLGIDDFSKIP
                     NGAPGVEHRLALLYTYGVLENRISVNKFVEVTSTNAAKIFGMYPKKGEIAVGSDADIV
                     ILNINKEETISYKTQKQNVDYTPYEGFKVKCKVEDVFLRGNHVVQSCNVKEHPTGQYI
                     KRKITK"
     gene            1842..3248
                     /locus_tag="ACGI5H_003489"
     CDS             1842..3248
                     /locus_tag="ACGI5H_003489"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728530.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="amidohydrolase family protein"
                     /protein_id="HFG9699176.1"
                     /translation="MMDILIKNAIIVTVNKEREVIFDGALVVKDNKIADIGNSKEIES
                     KYTDVKKIIDAKGKVLFPGFINTHNHLFQTLLKGLGDDMVLKDWLETMTFPAANYLEP
                     KDTYDAAMLGCIEGLRSGITTMVDYMYPHSKPGLCDGIIDAYKELGIRGILGRGCMNT
                     GAQFGVHPGIMQDVETVEKDVRRLFEKHHNTENGRIKIGVAPAAIWSNSQEMLEMLWR
                     VVKEYDDALFTVHISETPFDREAAKELHGQYDIDVLEKLGILGPNVLMVHCVYLTEKD
                     MELTKKYDMKVSHNTASNMYLSSGVAPVPEMLKKGITVSLGVDGAASNNSQDMLELMK
                     LTALQHKVNKCDPLAMSAEKVLELATIDGARAIGMEDEIGSLEIGKKADLLIFNPMLS
                     PKAIPMHNPVSTLVYSSSMKNIESVIVDGNIIMEDSKILTANEEKALKDAQDTAERLC
                     IRGTIKNRMEGHKWNSLY"
     gene            3320..3766
                     /locus_tag="ACGI5H_003490"
     CDS             3320..3766
                     /locus_tag="ACGI5H_003490"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902988.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="2Fe-2S iron-sulfur cluster-binding protein"
                     /protein_id="HFG9699177.1"
                     /translation="MIIKCTINNKEKELSIRPDDFLADTLRENGYVSVKKGCDTGSCG
                     LCTVMVNDKAVLSCNYLTARVEGQHITTLEGVLDEAKKFGDFLADEGADQCGFCAPGF
                     IMMVLAMKRELQNPTEEEVIDYVNGNLCRCTGYKGQLRAIHKYLNT"
     gene            3805..4599
                     /locus_tag="ACGI5H_003491"
     CDS             3805..4599
                     /locus_tag="ACGI5H_003491"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890208.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="FAD binding domain-containing protein"
                     /protein_id="HFG9699178.1"
                     /translation="MITIKEYVVPKSLDEAYELLISRKNNIILGGCGFLKLGSKNIGS
                     AIDLKDLALDYINETDDSILIGADTSLRTLELNKVIKNYCNGVISNAVSNIVGVQFRS
                     GARVGASVFAKYGFSDLIPSLLVVDAKVKLYKKGVMNLADFLENELEKDILIEVILPK
                     KDAIGVFDSIRKCTGDFAVLNGAMLKEGSIYKIAIGARPRRAKIAYKASEILSLENDI
                     EKAGEVSSEELSFGSNIRGSKEYRKDMTKALVVRMYNSIGGECDGK"
     gene            4589..6880
                     /locus_tag="ACGI5H_003492"
     CDS             4589..6880
                     /locus_tag="ACGI5H_003492"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890206.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="molybdopterin cofactor-binding domain-containing
                     protein"
                     /protein_id="HFG9699179.1"
                     /translation="MVNKEVRKIDSEAIVTGKPIYTEDLIFHKDVLTIKLLRSPHAFA
                     KIKNIDIKNALKVKGVVNIFTYKDVPNYRYSMVGESYPEASPHDQLILEDVVRYVGDE
                     VAIIAAEDERAAIKAMKLIKVEYEVMTPILDARESEGNKILIHEEDDLFCPFDFGLDA
                     TKNIVSREKMGKGDVEKEFKESDVIVEHSYMTQSQAHCMMETHRAYTYIDTNGRLVVT
                     SANQSAYHMRRQVSKALGIPLSKVRVIKPRIGGGFGGKNIAVTEIYASFVTWMTKRPA
                     KLIYTREETFAMTNTRHQMFFDIKIGADKEGNIKAIDMKALNNTGAYGDNGPSVCSES
                     GHNVLPTYNNVPAIKFDGKTVYTNLVPGGALRGYGATQGTFALDCAIDELAHKLNMDP
                     TEIKLKNIIKKQTEGGIMNFPIRSCALDECIIRGKKLIGWDEKYPVRDIGNNKVRAVG
                     MSVGTHGSGIANIDMAIVNMRMDEDGTYKLFSGSSDLGTGSDTILAQIAAKALNTSID
                     RISVYTGDTDMCPYDTGAYASCTTYVTGNATIKSAESLKQKILKVAQKKLDLPIDDLI
                     LYEDRVCYSEDVEKFVLLSELGKESVGGGNQEVLYSSESYGIQESAKPFLAGFAEIEL
                     DKTTGEFKVINYACSTDCGTVMNPALARIQVEGGVTQGIGLAMYEDPRHGSDGKLQTS
                     NLLQYKVPTKKDIGNIIVDFVDNYEPTGPYGAKSLGEIVIHTPAPAIANAIYNATGVR
                     IRELPITSEKVYMAMKKLNQGGK"
     gene            6881..8194
                     /locus_tag="ACGI5H_003493"
     CDS             6881..8194
                     /locus_tag="ACGI5H_003493"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890204.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="amidohydrolase family protein"
                     /protein_id="HFG9699180.1"
                     /translation="MIAIKSKYLISSADEIYTNSAVVVENDIIKDILPNEEVEIKYKN
                     IEEIIDKSDAIIMPGFVNGHMHQYGVLSRGIPANVHFTDFEGFLNDYWWPFIENRIGL
                     KEVKATTKASAIELIESGVVAFCDTLEAPNTEEGTLIEQGKILEEIGMKAILSLESCE
                     RISFENGLRCLDENSNLIKWSRENSKLINGIMCTHTSFTCSDRFIKKAKEDAKKLNAP
                     MQFHLCESIYEPNYAEKHFGKKAVDYYNDLDILDETVLASQCVKVNDEEIDILKEKGV
                     KVVHMPLSNCEVGGGFSPVPKMIKKGIKVALGTDGYINDFFEVMRGAFLMHKSVEEDA
                     SVMPANLVFRMATEHGAYVLGLQNSGKIAVGNKADIIVMEDEFKTPVTLDNIFDQIVV
                     QGKKEFISNVYIDGRHILKEKQLVDLDKKAIVKEMKEVACEFWKF"
     gene            8230..9315
                     /locus_tag="ACGI5H_003494"
     CDS             8230..9315
                     /locus_tag="ACGI5H_003494"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902986.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroorotate dehydrogenase"
                     /protein_id="HFG9699181.1"
                     /translation="MYNFLGKELKSPLIIGSGPLTYSAAGCKILSDAGAGAVVTKTIR
                     KERAINPAPHMVRNTANALLNNEKWTDFEPEQWIDFEIPQMKRDGTVCIASIGHTIEE
                     SSELVEKVANAGADFIELVSYDYRDLIPMLKDAKERVNIPVIVKLPPMIDEIGDFAKK
                     LEEAGADAITACDSVGPAFRIDIETGQPLLGGNGIGYLSGETIKPITLQRIYEIKKQV
                     NIPIIGLGGCVSGDDALEMIMAGADFVGICSVVILKGAQVISKIHDDLKSNLNRLGYN
                     TIENACGIVHNHMGDVNERLSFEFTYDEEKCTKCKMCERVCAYQARKLNDKMELNEEE
                     CRYCGLCISVCKPKALGRKISCSELNV"
     gene            9551..10594
                     /locus_tag="ACGI5H_003495"
     CDS             9551..10594
                     /locus_tag="ACGI5H_003495"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012816238.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9699182.1"
                     /translation="MQVQEKILELLYTINEDVVSIKNDMSEVKQEINVLKEDMSEVKQ
                     EMTVMKEDMSEVKQEINVLKEDMSEMKQEMTVMKEDMSEVKQEINVLKGDMSEVKQEM
                     IVMKEDMSEVRQEINIMKEDMSEVRQEINTMKEDMSEVRQEMTVMKEDMSEVKQEINV
                     LKEDMSEVRQEINIMKEDMSEVRQEMTVMKEDTSEVKQEINVMKKDMSEVRQEITVMK
                     EDVSEVKSEVNFMQNKINNINEDMNGIKDEVSIANEKLYGIEIKIDSLECEDKSMKEI
                     QIEQNNILGSLLHNSEINKATHDNIEHNIAYIKGDTNSIKEDIAEIRRDLNLVELATS
                     KNWSDIVKLKSVK"
BASE COUNT         4298 a         1119 c         2172 g         3091 t
ORIGIN      
        1 gttgaaaaag ctgattgcta tacaggaaat actatagaaa gtgaaagatt cttcccaggt
       61 tggttatatg acgaagaaga tgaatttgtt caagcagcgt ataagggatt aaaagaagct
      121 ggaatagatt cagaaataac tcaatactca ttctgtacga atggaagtca ctatgcaggt
      181 gaagctggaa taaaaactat aggatttggt ccttctaagg aaaatcttgc tcacacaata
      241 gatgagtata tagagcaaga acagttattt ataggaacag aaggttacta tggaatatta
      301 aaatctgtat acggaaaata atatttagtt cacaataaat tatttaaata tagtctagag
      361 gtgctgaata tagcaccttt agaaaataca attttaaata aagttttaca atacttagaa
      421 aatactttaa agcttaaaag ttaggaggta tatatgggaa caatactaag aggtggaact
      481 ataattacct ctgataagac ttatataagt gatttaagga tagaagatga aaagatagtt
      541 gaaataggaa ataacttaga aataaatggt gataaggtta ttgatgctac aggtaaaatt
      601 gtaattcctg gtggaataga cacacatact cattttgata tgaatgcagg ttctattaca
      661 actgcagata attttgaaac aggaacaaga gcagctatag ctggaggaac tactacaata
      721 ctagattttg cagaagccaa tgagggggaa aatctactgc aaggtgtaga agcatatcat
      781 aaaaaagcaa gtggaaattg ttattgtgat tatggttttc atatgacaat tacatgttta
      841 aataaagata catttaatca tatggaaaaa cttatttcag atgggatagt atcttttaag
      901 atgtatatgg catatgatgg catgaaagta gatgatggaa caatatacag ggttttaaag
      961 aaagcaaggg atttaggttg tatagttgga tttcattgtg aaaatgggga tttactagat
     1021 gtattgatag aagaaaatat acaaaatggt aatttggagc caaaatatca tccacttaca
     1081 agacctaaca tagttgagaa agagtctgtt tcaagacttg ctgatataac taaattatct
     1141 aattcaaaat cctatgtagt ccacttaagt tgtagggagt cacttgaaac tgtaaaaata
     1201 gctagagaaa aaaatataga tatgatagta gaaacatgcc cacagtatct attattagaa
     1261 gacaatttat ataataagga taaatttgag ggtgctaagt atgtaatgtc tcctccttta
     1321 agaaaaaaag aagacataaa ttacctttgg gaaggattgt ctagtggaga tattcaaaca
     1381 gttggcacag accactgttc atttaatttt aaggggcaaa aagacttggg aattgatgat
     1441 ttcagtaaga taccaaatgg agcacctggt gttgaacata ggttagcact tttatataca
     1501 tatggggtct tagaaaatag aataagtgta aataagtttg tggaagttac ttctacgaat
     1561 gctgcaaaaa tatttggaat gtatcctaaa aaaggtgaga tagctgtagg aagtgatgca
     1621 gatatagtca ttttaaatat caataaagaa gaaacaatta gttataaaac tcaaaaacaa
     1681 aatgtagatt atactccata tgaaggattt aaggttaaat gtaaagttga agatgtattt
     1741 ttgagaggaa atcatgtagt acaaagttgt aatgttaaag aacatccaac aggtcaatat
     1801 attaaaagaa aaattactaa ataatgcggg gggaaataag aatgatggat atacttatta
     1861 agaatgccat aatagtaact gtgaataaag agagagaagt tatttttgat ggggcattag
     1921 tagtaaaaga taacaagatt gctgatattg gaaattctaa agagatagaa agtaaatata
     1981 ctgatgttaa aaaaattata gatgctaaag gtaaagtttt attcccaggt tttataaata
     2041 cacataatca tttattccaa actttattaa aaggattggg agatgatatg gtacttaaag
     2101 actggttaga aactatgaca tttccagcag ctaactattt agagcccaaa gatacttatg
     2161 atgctgcaat gcttggatgt attgaaggac ttagaagtgg tataacaaca atggttgact
     2221 acatgtatcc tcatagtaag ccaggtcttt gtgatggaat aatagatgct tataaagaat
     2281 taggaataag aggaatactt ggaagaggat gtatgaatac aggagctcaa tttggagttc
     2341 atcctggaat aatgcaagat gtagaaacgg ttgaaaaaga tgtaagaaga ttgtttgaaa
     2401 aacaccataa tacagaaaat ggaagaatca aaataggagt agctcctgca gcaatatggt
     2461 caaattctca agaaatgctt gaaatgctat ggagagtagt aaaagaatat gatgatgctt
     2521 tatttacagt acatatatca gagactcctt ttgatagaga agcagcaaaa gaattgcatg
     2581 ggcaatatga catagatgtt ttagaaaaat taggaatact tggaccaaat gtgcttatgg
     2641 tacattgtgt gtatctaact gaaaaagata tggaacttac taaaaaatac gatatgaaag
     2701 tgtctcataa tacagcaagt aatatgtact tatcttcagg tgttgcacca gtgccagaaa
     2761 tgcttaaaaa aggaataaca gttagtttag gagtagatgg agccgctagt aataactctc
     2821 aagatatgct tgaacttatg aaattaacag cacttcaaca taaagttaat aagtgtgacc
     2881 cattagcaat gtcggcagaa aaagttcttg agttggcaac tatagatgga gcaagagcta
     2941 ttggaatgga agatgagata ggttcattgg agataggtaa aaaagcagac ttactaatat
     3001 ttaatccaat gctttcacca aaagcgatac ctatgcataa tccggtatct acattagtat
     3061 attcttctag tatgaaaaat atagagagtg ttatagtaga tggaaatata ataatggaag
     3121 attcaaaaat attgacagct aatgaagaga aagcattaaa agatgctcaa gatacagctg
     3181 agagactttg tataagagga actataaaaa atagaatgga aggtcataaa tggaatagcc
     3241 tttattaata aatgtaattt attcataaaa aagtatagta aaactttagc ttaaaaatat
     3301 gagttttgag gtgatttatt tgattatcaa atgtaccata aataataaag aaaaagaatt
     3361 aagtataaga ccagatgatt ttttagcaga tacattaaga gaaaatggat atgtaagtgt
     3421 taaaaaaggg tgtgatacag gctcatgtgg gttatgtaca gtgatggtaa atgacaaggc
     3481 cgtgctttca tgtaattatc ttactgctag agtagaaggt cagcatatta caacacttga
     3541 gggtgtcttg gatgaagcaa agaagtttgg agattttctt gcagacgaag gggctgacca
     3601 gtgtggattt tgtgctcctg gatttataat gatggtcttg gcaatgaaaa gagagcttca
     3661 aaatccaaca gaagaagaag ttatagatta tgtaaatggt aacctttgta gatgtacagg
     3721 atataaaggt caattaagag caatacataa atatttaaac acttagactt ttaagtgaaa
     3781 attaagttga tatggggaga gagtatgata actataaagg aatatgtagt tccaaaaagt
     3841 ttagatgaag cttatgaact gctaatatca agaaaaaaca acataatact tggaggatgt
     3901 ggatttttaa aactaggtag taaaaatatt ggttcagcaa tagatttaaa agacttagct
     3961 ttagattata taaatgaaac tgatgatagc atattaattg gagcagatac aagtttaaga
     4021 actttagaat taaataaggt tattaaaaat tactgtaatg gggtaatttc aaacgctgtt
     4081 tctaatatag taggagttca atttagaagt ggagctagag taggagctag cgtatttgct
     4141 aagtatggat tttcagattt aataccttca ttactagtgg tagatgcaaa ggttaagtta
     4201 tataaaaaag gggttatgaa cttagctgat tttttagaaa atgagcttga aaaagatata
     4261 ttaatagaag ttatattacc taaaaaagat gctataggtg tatttgattc tataagaaaa
     4321 tgtacaggtg attttgcagt attaaatgga gcaatgttaa aagaaggaag tatttataaa
     4381 attgcgatag gcgctagacc aagaagagca aaaattgcct ataaagcaag tgaaatatta
     4441 agtttagaaa atgatataga aaaagctggt gaagtatcaa gtgaagaact ttcatttgga
     4501 agtaatataa gaggaagtaa agaatacaga aaagatatga caaaagcctt agtagtgaga
     4561 atgtataata gtattggagg tgagtgtgat ggtaaataaa gaggtaagaa aaatagatag
     4621 tgaagccatt gttactggaa aaccaatata tacagaagat ttaatttttc ataaagatgt
     4681 tttaacaatt aagcttctta gaagtccaca tgcttttgcg aagataaaaa acatagatat
     4741 aaaaaatgca ttaaaggtaa aaggtgtagt aaacatattc acttacaaag atgttccaaa
     4801 ttatagatat tcaatggttg gagagtcata tccagaagca tcacctcatg accaattaat
     4861 acttgaagac gtagttagat atgtaggaga tgaagttgct ataatagccg ctgaagatga
     4921 aagggctgct attaaagcta tgaaacttat aaaagttgaa tatgaagtaa tgactcctat
     4981 attggatgca agagaatcgg aaggaaataa aattttaatc catgaagaag atgatttgtt
     5041 ttgtccattt gattttggat tggatgctac aaaaaatatt gtatcgagag aaaaaatggg
     5101 taaaggggat gtagaaaaag agtttaaaga aagtgatgta atagtagaac attcttatat
     5161 gactcaatca caagcccatt gtatgatgga aactcataga gcttatacgt atatagatac
     5221 gaatggcaga ttagtagtaa cttctgcaaa ccaatcagct tatcatatga gaagacaggt
     5281 ttctaaagca ctgggaatac ctctttcaaa agtgagagta ataaaaccaa gaataggtgg
     5341 aggttttggt ggaaaaaaca tagctgtaac agagatatat gcatcatttg taacttggat
     5401 gacaaaaaga ccagcaaaac taatttatac tagagaagaa acttttgcaa tgactaatac
     5461 tagacatcag atgttttttg atataaaaat tggggcagat aaagaaggaa acataaaagc
     5521 tatagatatg aaagcattga acaatacagg cgcttatggc gataatggac cttcagtttg
     5581 ctctgaatca ggtcataatg tacttccaac atataataat gtacctgcaa taaaatttga
     5641 tgggaaaact gtatatacta atttagttcc aggaggagca ttaagaggat atggagcaac
     5701 acaaggtaca tttgcacttg attgtgcaat tgatgaatta gcgcataaac ttaatatgga
     5761 cccaacagaa ataaagttaa agaatattat aaaaaaacaa actgaaggcg gaataatgaa
     5821 ttttccaata agaagttgtg cacttgatga atgtataatt agaggtaaaa aacttattgg
     5881 atgggatgaa aagtaccctg ttagggatat tggaaacaat aaggtgaggg ctgttggaat
     5941 gtctgtggga actcatggtt ctggtatagc caacatagac atggcaatag taaatatgag
     6001 gatggatgaa gatggaactt ataagttgtt ttctgggtct tcagacttag gaactggttc
     6061 tgacacaata cttgcacaaa tagctgcaaa agcattgaat acatctattg atagaatttc
     6121 cgtttataca ggagatacag atatgtgtcc atatgatact ggtgcatacg cttcttgtac
     6181 tacttatgta actggaaatg ctacaataaa atctgctgaa agtttaaaac aaaagatatt
     6241 aaaagtagca cagaagaaac tcgatttacc aatagatgat ttaatactat atgaagacag
     6301 agtttgttat agtgaagatg tagagaagtt tgttttgtta agtgaattag gaaaagaatc
     6361 tgttggtggt ggaaatcaag aagttttata ttcatctgaa tcttatggta tacaagagag
     6421 tgctaaacca ttcttagcag gatttgctga aatagagtta gataaaacaa caggggagtt
     6481 taaagtaata aattatgctt gttctacaga ttgtggtaca gttatgaatc ctgcacttgc
     6541 tagaatacaa gttgaaggtg gtgtaactca aggtataggg cttgcaatgt atgaagaccc
     6601 tagacatggt tctgatggaa agcttcaaac ttctaatcta ttacaataca aagttccaac
     6661 aaaaaaagat ataggaaaca taattgttga ttttgtagat aattatgagc caacaggtcc
     6721 atatggagct aaatctttag gagaaatagt tattcataca cctgcaccag caatagcaaa
     6781 tgcaatatac aatgccacag gagttcgtat aagagaactt cctataactt ctgagaaagt
     6841 ttatatggcc atgaaaaaat taaatcaggg aggtaaataa atgattgcta ttaaaagtaa
     6901 atacttaata tcttctgctg atgaaatata tacaaattct gctgttgtag tagaaaatga
     6961 cattataaaa gatatattgc caaatgaaga agttgaaata aaatataaaa atattgaaga
     7021 aataatagat aaatcagatg ctataataat gccaggattc gtcaatggtc atatgcatca
     7081 atatggagtt ctttctaggg gaataccggc aaatgtacat tttactgact ttgaaggttt
     7141 tttaaatgac tattggtggc catttataga aaatagaatt ggattaaaag aagtgaaggc
     7201 aacaactaaa gcatcagcaa tagaacttat agaatctggt gtggtagctt tttgtgatac
     7261 cctagaagct ccaaatacag aagaaggaac tttaattgag caaggaaaaa tactagaaga
     7321 aataggcatg aaagcgattt tatccttaga aagttgtgaa agaataagct ttgaaaatgg
     7381 acttagatgt ttagatgaaa attctaattt aataaagtgg agtagagaaa atagtaaatt
     7441 aataaatgga ataatgtgta cacatacaag cttcacatgt tctgatagat ttattaagaa
     7501 agctaaagaa gatgcaaaaa aattaaatgc accaatgcaa tttcatttat gtgagagtat
     7561 atatgagcca aactatgctg aaaaacactt tggcaaaaaa gcagttgact actataatga
     7621 tttagatata ttggatgaaa ctgtattagc atctcagtgt gtaaaagtaa atgatgaaga
     7681 aatagatata ttaaaagaaa aaggcgtaaa agtggttcat atgcctctta gtaactgtga
     7741 agtaggtgga ggtttttctc cagtaccaaa aatgattaaa aaaggcataa aagtggcact
     7801 gggtactgat ggatatataa atgatttttt tgaagttatg agaggtgcat ttttaatgca
     7861 taaatcagtt gaagaagatg catcagtaat gccagcaaat ttagtattta gaatggcaac
     7921 agagcatggt gcttatgtat taggacttca aaattctggt aaaatagcag ttggtaataa
     7981 ggctgatata atagttatgg aagatgaatt taaaactcct gtgactcttg ataatatatt
     8041 tgaccagata gtagttcagg gtaaaaaaga atttatatca aatgtataca tagatggtag
     8101 acatatttta aaagaaaaac agttagttga tttagataaa aaagctattg ttaaagaaat
     8161 gaaagaagtt gcttgtgaat tttggaaatt ttaacgaatg taaatatata tgaaaagggg
     8221 aagcagataa tgtataattt tttaggtaaa gaattaaaat caccacttat aataggttca
     8281 ggaccattaa catatagtgc agctggatgc aagatattaa gtgatgcagg agcaggggca
     8341 gttgtgacta agactataag aaaagaaaga gctataaatc cagcaccaca tatggttaga
     8401 aatacagcta atgctctttt aaataatgaa aaatggacag attttgagcc agagcaatgg
     8461 atagattttg aaataccaca aatgaaaaga gatgggactg tctgtatagc ttcaataggt
     8521 catacaattg aagaaagtag cgaattagta gagaaagttg caaatgcagg agctgacttt
     8581 attgaattag tatcttatga ctatagagat ttgataccaa tgcttaaaga tgcaaaggaa
     8641 agagtaaata tacctgtaat agttaaactt cctcctatga tagatgagat aggcgatttt
     8701 gctaaaaaat tagaagaagc aggagcagat gcaataactg cttgtgactc tgtaggacca
     8761 gcatttagaa tagacataga aacagggcaa cctttattag gtggaaatgg aataggatat
     8821 ttaagtggag aaactatcaa gccaataact ttacagagaa tatatgaaat aaaaaaacaa
     8881 gttaatatac caataattgg cttaggtgga tgtgtaagtg gagatgatgc cttagaaatg
     8941 attatggcag gtgctgactt tgttggtata tgttcagtag taattttaaa aggtgcacaa
     9001 gtaatatcta aaatacatga tgatttaaaa tctaatctta atagattagg atataatact
     9061 atagaaaatg cttgtggtat agtacataat catatgggag atgttaatga aagacttagc
     9121 tttgagttta cttatgatga agaaaaatgt actaaatgta agatgtgcga gagagtttgt
     9181 gcatatcaag cgagaaaatt gaatgataag atggaattga atgaagaaga gtgtagatat
     9241 tgtggacttt gtatatcagt ttgtaaacca aaagcacttg gaagaaaaat ttcatgttca
     9301 gagctgaatg tatagattat tttataaaaa acaaagtttt aaataaaaat aagaaaggct
     9361 atctcaaaga gataagcctt ttttgttgtt gaccttattt ttgtttattt gtagttattt
     9421 tagatattaa ttagttttga agtaataaag tgaatcaatt ttgtttaatt aaaattttaa
     9481 taattctgat atatatgtta acattgtata gcatttgtgt aaaatgttat aataattaat
     9541 agggatggtg atgcaagtgc aagagaagat tttagagtta ttatatacta taaatgaaga
     9601 tgtagttagc ataaaaaatg atatgtcgga agtaaaacaa gaaataaatg tgttaaaaga
     9661 agatatgtcg gaagtaaaac aagaaatgac tgtaatgaaa gaagacatgt cggaagtaaa
     9721 acaggaaata aatgtattaa aagaagatat gtcggaaatg aaacaagaaa tgactgtaat
     9781 gaaagaagat atgtcggaag taaaacagga aataaatgta ttaaaaggag atatgtcaga
     9841 agtaaaacag gaaatgattg taatgaaaga agatatgtcc gaggtaagac aagagataaa
     9901 tataatgaaa gaggatatgt ccgaggtaag acaagagata aatacaatga aagaggatat
     9961 gtcggaagta agacaagaaa tgactgtaat gaaagaagat atgtcggaag taaaacagga
    10021 gataaatgta ttaaaagaag atatgtccga agtaagacaa gagataaata taatgaaaga
    10081 agatatgtcc gaagtaagac aagaaatgac cgtaatgaaa gaagatacat cagaggtaaa
    10141 acaagagata aatgtaatga aaaaagacat gtcagaagtg agacaagaaa taactgtaat
    10201 gaaagaagat gtttccgaag ttaaatcaga agtaaacttt atgcaaaata aaataaataa
    10261 cattaatgaa gatatgaatg gaattaagga cgaggtatcc atagcaaatg aaaaattata
    10321 tggaattgaa attaagattg atagtctaga atgtgaagat aaatcaatga aagagataca
    10381 gatagaacag aataatattt taggaagttt attacataat tctgaaataa ataaagctac
    10441 tcatgataat atagaacata acatagcata tataaaaggt gacactaatt ctataaaaga
    10501 ggatatagct gaaataagaa gagacttaaa tttagtagag ttagccacta gtaaaaattg
    10561 gagtgatatt gtcaaactaa aatcagtaaa gtagtatttt aattcactaa tttatcatcc
    10621 acaaactaag aattttatat aaaagaattt atagtgttct tactatttat tataaatttt
//
LOCUS       DAYAOO010000118        10307 bp    DNA     linear   BCT 12-OCT-2024
DEFINITION  TPA_asm: Clostridioides difficile isolate ST8-SSI-h139-18
            SAMN40601845-rid21577343.denovo.122, whole genome shotgun sequence.
ACCESSION   DAYAOO010000118 DAYAOO010000000
VERSION     DAYAOO010000118.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN40601845
            Sequence Read Archive: SRR28438827
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 10307)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10307)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-MAY-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-MAY-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002157583.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002157583.1
            Genome Coverage       :: 163x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/11/2024 16:19:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 4,038
            CDSs (total)                      :: 3,963
            Genes (coding)                    :: 3,930
            CDSs (with protein)               :: 3,930
            Genes (RNA)                       :: 75
            rRNAs                             :: 6, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 60
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 33
            CDSs (without protein)            :: 33
            Pseudo Genes (ambiguous residues) :: 0 of 33
            Pseudo Genes (frameshifted)       :: 7 of 33
            Pseudo Genes (incomplete)         :: 25 of 33
            Pseudo Genes (internal stop)      :: 11 of 33
            Pseudo Genes (multiple problems)  :: 8 of 33
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10307
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN40601845-rid21577343.denovo.122"
                     /isolate="ST8-SSI-h139-18"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Denmark"
                     /collection_date="2018"
                     /collected_by="Statens Serum Institute"
     gene            391..1551
                     /locus_tag="ACGI5H_003496"
     CDS             391..1551
                     /locus_tag="ACGI5H_003496"
                     /EC_number="2.7.7.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892825.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008878 - glucose-1-phosphate
                     adenylyltransferase activity [Evidence IEA];
                     GO_process: GO:0005978 - glycogen biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-1-phosphate adenylyltransferase"
                     /protein_id="HFG9699183.1"
                     /translation="MKKEMLAMILAGGQGSRLGVFTKRIAKPAVSFGGKYRIIDFVLS
                     NCSNSGIDTVGVLTQYRPLILNSHIGMGSHWDLDRINGGVYVLQPFMNEKEGNWYNGT
                     AHAIYQNMDFVDTYNPEYVLILSGDHIYKMDYSKMLKFHKEKGSKATIAVIEVPWDEA
                     SRFGIMNTNEDSSIYEFEEKPSEPKSNLASMGVYIFDWKMLRNYFKEAEKNPEINYDD
                     FGKNLIPKMLEDNVGMYAYPFKGYWRDVGTIQSLWDANMDIIKSPETLDLADPKWKIY
                     TNTMAMPPQYIGKNANVHRSMIADGCRILGEVGNSVLSHGVVVGKGSKVIDSVIMPNV
                     VIGENVTIEKAMIGECATINDNVQIKNVNNEINVVSEYENIEPRCVLIEGGL"
     gene            1553..2683
                     /gene="glgD"
                     /locus_tag="ACGI5H_003497"
     CDS             1553..2683
                     /gene="glgD"
                     /locus_tag="ACGI5H_003497"
                     /EC_number="2.7.7.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004453566.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008878 - glucose-1-phosphate
                     adenylyltransferase activity [Evidence IEA];
                     GO_process: GO:0005978 - glycogen biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-1-phosphate adenylyltransferase subunit
                     GlgD"
                     /protein_id="HFG9699184.1"
                     /translation="MRNECLGIINLNKKGDPAINKLNYGRPIASTPIAGRYRIIDFAL
                     SNMINSGITKVGIFAKEKYRSLTDHIGSGKDWDLSRKKGGLSIFSPENTKYRNTYSHR
                     EGDIYTILANLDYIEKSEEEYILIAPSYMLCNLNYSQALEYHKKSHNDITIIYKNVNN
                     ANKDFAGNLTLNLDSNNRVINVGNNLGKFPRANICMETYIMKREDFVECIYNIVNKGN
                     YCYLEEFIIEEAENMKIGAYEYTGYLKCVNSVESYFEMSKDLLNLEVADELLYSERKI
                     FTKEKNESPTIYTDSAKVENSFIASGCLIEGTVKDSIIFRKVNVEKGTVIENSIVMQN
                     CVIKSNAKLYNAILDKNTSVSNGKELRGDEKYPLVVEKNTNI"
     gene            2712..4154
                     /gene="glgA"
                     /locus_tag="ACGI5H_003498"
     CDS             2712..4154
                     /gene="glgA"
                     /locus_tag="ACGI5H_003498"
                     /EC_number="2.4.1.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860977.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004373 - glycogen (starch) synthase
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycogen synthase GlgA"
                     /protein_id="HFG9699185.1"
                     /translation="MKVFYVTAECWPFAKTGGLGDVSYALPKELKKEGVDVRVIMPKY
                     STIPSYLKDQLKEIAVFSVRVGWRNQYCGLLEMELDGVKFYFIDNEFYFRREDERKSI
                     YGYGDDAERYTFFTDAVLEAISRIDFYPDVIHINDWHTGMLPLILKERYATLEGYKNI
                     KTMYTIHNLQYQGVFDKHVLYDILDLPQKYFDNGDIEYYGSINFMKAGINFADKIITV
                     SPTYANEIQTSFYGEQLDGLLRKESGKLKGILNGIDYDLNDPAKDKDIFVHYDVDSID
                     KKVENKLRLQDILGLKKDSSIPLIGIVSRLVSQKGFDLIAYMMPELMREDLQIVVLGT
                     GEHQYQSMFNYYDSNFSDKVSARITFNASLAQQIYAASDMFLMPSLFEPCGIGQMLAM
                     RYGSLPIVRETGGLRDTVTPYNKFTGEGNGFSFKNYNAHEMFFCLKNAIKVFKDKEKW
                     IKLVENAMKTDNSWKKSAKEYIETYRDICD"
     gene            4168..6588
                     /locus_tag="ACGI5H_003499"
     CDS             4168..6588
                     /locus_tag="ACGI5H_003499"
                     /EC_number="2.4.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895917.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycogen/starch/alpha-glucan phosphorylase"
                     /protein_id="HFG9699186.1"
                     /translation="MVTISKKKFKQKFEVKMYSLYAQSIKEATDEQLLNVLCSLLKDE
                     IAKKWVATKLDKKKEVYYFSLEFLIGRQLKSNLLNLNIEEEVREGLSELGINLDDLIE
                     AEVDPALGNGGLGRLAACFLDSMASLNISGQGYGIRYKYGLFEQKFVNGYQVEVPDNW
                     LTEGRYAWETVRPNEATMVKFGGEVELIKEGSHLKVIHKNYLPVMAMPYDIPIIGYQN
                     QCINTLRLFKSEIPKRDFGELTSNALNYSGSYEEALKHKYYTEEISQVLYPDDSNYAG
                     KLLRLKQEYFFVSAGIQDIIRKYKKNKLNINNLFDKVAIHINDTHPTLCIPELMRVLL
                     DEENLSWDEAWEITKKTVSYTNHTIMSEAMEKWPVSMMKELLPRIYMIIEEINRRYVE
                     ELNNKGYDQDRIKRMSIIDCDNINMANLCIVTSHSVNGVAKLHTHILETEVLKDFYQD
                     EPNKFNNKTNGIAHRRWLISSNPQLSNLITDLIGDSWKKDTLQLKNIEKFKNDSSVLQ
                     RLDDIKYNNKANLAKFIKDKYDLNVDPSSIFDVQVKRLHAYKRQLLNIFNVLHMYHEL
                     LDNPNLNLDPRTFIFGAKAAPGYYLAKCIIKFINSVASTINNDVRVKDKLKVVFLENY
                     GVSLAEIIIPAANVSEQISTTTKEASGTSNMKFMMNGAITLATLDGANVEICEQVGKE
                     NMFLFGLSAEQVLNYNKYGGYSSLDLYHSNMDIKRVVDDLINGFIPNLGEEGRSIYNS
                     LTTYNDEYFVLRDFENYGQAQADINRLYRDKEKWNKMSLVNIANSGFFSSDRTISEYA
                     KDIWFKRV"
     gene            6593..8458
                     /locus_tag="ACGI5H_003500"
     CDS             6593..8458
                     /locus_tag="ACGI5H_003500"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728711.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 13 protein"
                     /protein_id="HFG9699187.1"
                     /translation="MQSVIEYNSWDKNFKAPFGALKFDEELTICVKVNEGYNIKSISL
                     EINREEEMRTITLNEELDNDKLGKCFCGKIEKFDGTGVYFYYFKVDVEMDGQIKTLFY
                     GKNRDNGYSCEYNYSDINKYQITVYKDFKVPTWYKEGILYHIFVDRFNNGNRSGKVDN
                     PKKNSFIYGNWEDTPMYIKDSQGDVIRWDFHGGNLRGIINKLGYLKKLGVSILYLSPI
                     FEASSNHKYDTGDYKKIDPMFGDEDTFKELIDKAKEKGISIVLDGVFSHTGADSKYFN
                     MYGNYNSLGAYQSKESPYYSWYMFEEFPQKYKSWWDVKTLPNINELEHSYMDYIIYDN
                     DSVINKWVNMGIKGWRLDVADELPTKFIRELKKELKKADDDSILIGEVWEDASNKISY
                     GQRRSYLLGEELDSVMGYPFRNNMFSFLKGEINSYELCNRYMQIKENYPKESFRSNLN
                     LIGTHDVTRAKTELNDDVDLVKLAVAIQMTFEGVPYIYYGDEAGLCGGVDPDNRRTYP
                     WKNEDEDMLNFYRDVIRIRNKNKLLSSGNTEFIYTNNDSVFSFIRVNENNDRMLILVN
                     RSENVESISLCIESSFIEEIPIKYSLKNANSTIQIENNELKVDLDSKSFRIFRVN"
     gene            8703..9356
                     /locus_tag="ACGI5H_003501"
     CDS             8703..9356
                     /locus_tag="ACGI5H_003501"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888720.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HFG9699188.1"
                     /translation="MKVDPLTTQVYDYISKKIQNGEYEANQRITESEICKSIGVSRTP
                     AREALTRLAGENLLEKIPNKGFVVKEFQEKEKLDTYSVIGVLDALAGSSALQNLTESD
                     LVKMEELTEMMAVSIKYKNYNSYLKLSNEFHDIYITKSDNQVLVNLLNSLRYNFMSKS
                     YTSDNEDELYKMLTYSNNQHIEVVKSMRENDLENVERILREHWKTIPMEEMKKEKLL"
     gene            9452..10051
                     /locus_tag="ACGI5H_003502"
     CDS             9452..10051
                     /locus_tag="ACGI5H_003502"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004453558.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HD domain-containing protein"
                     /protein_id="HFG9699189.1"
                     /translation="MYPNKEIAIEELEVAGKMNPGPWIKHSYNVANVAKLIAEQCENL
                     NSEKAFVCGLLHDIGRRTGISSVRHIIDGYDYVISKGWDEVARVCLTHSFPVKDIEAD
                     IGNKDISKEQYDFINHYLNNLEYNDYDKLIILCDALADANGFCILEKRFVDTTRRYGI
                     YPFSVERWNKTYEYKEYFEKIINKSIYTLLPNIEKSIYY"
BASE COUNT         4143 a         1004 c         1873 g         3287 t
ORIGIN      
        1 aataattact tgattttcct tggataatta tttaacaaat attagattat attttgctat
       61 tacgaattta acaaattaaa aaataagcat gttcatatga cacaaaggat ttataaaaaa
      121 tgtttttata tttataaaat aaaatttgta ttatttttta accgataatt gaatattaat
      181 aaatactata gtgcttatgg aaaataatgt atacgtcggt aagtccatta tggggtatac
      241 attatatcaa ttgtatagtt gatattattt tatttttatt aaggtattat ttaagcaaca
      301 tttatacacg acatttattg actgataaag tttataaaag taaaaatgca attataaata
      361 ttaattacta gatgagggga gtgtcattaa atgaaaaaag agatgttagc tatgattttg
      421 gcaggagggc aaggttcaag attaggtgtt tttacaaaaa gaattgccaa accagctgta
      481 tcatttggag gtaagtatag aattatagat tttgtgttaa gcaattgttc aaactctggt
      541 attgatactg taggtgtttt aactcaatat agaccgttga tattaaattc acatataggc
      601 atgggaagtc attgggattt ggacagaata aatggtggtg tctatgtttt acaaccattt
      661 atgaatgaaa aagaaggaaa ttggtataat ggtacagcac atgcgatata tcaaaatatg
      721 gactttgtag atacctataa tccagaatat gtattgatat tatctggtga ccatatatac
      781 aagatggatt atagcaaaat gttaaaattt cataaggaaa aaggctctaa agctacaata
      841 gcagtgattg aagttccttg ggatgaagct tcaagatttg ggataatgaa tacaaatgaa
      901 gattcaagta tctatgaatt tgaagaaaaa ccaagtgaac ctaagagcaa tttggcatct
      961 atgggagtat acatatttga ttggaaaatg ttgagaaatt attttaagga agcagaaaaa
     1021 aatccagaaa taaattatga tgattttgga aaaaatttaa tacctaaaat gttagaagat
     1081 aatgttggaa tgtatgctta tccatttaaa ggatactgga gagatgtagg aactatacaa
     1141 agtctatggg atgctaatat ggatataata aaatctccag aaacacttga tttagcagac
     1201 cctaagtgga agatatatac aaatactatg gcaatgcctc cacaatatat aggtaaaaat
     1261 gcaaatgttc atagatcaat gatagctgat ggttgtagaa ttttaggtga agtaggtaac
     1321 tctgtattat cacatggagt tgttgttggt aaaggaagta aagtaattga ttcagtaata
     1381 atgccaaatg ttgtaatagg tgaaaatgta actatagaaa aagctatgat aggtgagtgt
     1441 gcaactataa atgataatgt tcagataaag aatgtaaata atgaaataaa tgtagtttct
     1501 gagtatgaaa atatcgaacc tagatgcgta ttaatagaag gaggtcttta agatgagaaa
     1561 tgaatgttta gggataataa atttaaacaa aaaaggagac ccagcaataa acaaacttaa
     1621 ctatggaaga ccaatagcat ctacaccaat agctggaaga tatagaataa tagactttgc
     1681 tttatctaat atgataaatt caggaatcac taaagttgga atattcgcaa aagaaaaata
     1741 cagatcatta acagaccata taggtagtgg taaagattgg gatttaagta gaaaaaaagg
     1801 tggcctatca atttttagtc cagaaaacac taagtataga aatacttact cacatagaga
     1861 aggtgatata tatactatct tagctaatct agattatata gaaaagagtg aagaagaata
     1921 tattttaata gctccaagct atatgctatg caatttaaat tattctcaag cattggaata
     1981 ccataaaaaa tctcataatg atataactat aatatataaa aatgtaaata atgcaaataa
     2041 agattttgct ggtaacttaa ctctaaattt agatagtaac aatagggtaa taaatgtagg
     2101 aaataattta ggtaagttcc ctagagcaaa catatgtatg gagacatata ttatgaagcg
     2161 tgaagatttt gttgaatgta tatataacat tgtaaataaa ggcaattatt gttatttaga
     2221 agaatttatt attgaagaag cagaaaacat gaaaatagga gcctatgaat atacaggata
     2281 tctaaaatgt gtaaattctg ttgaatcata ttttgaaatg agcaaagatt tattaaattt
     2341 agaagttgca gatgaattat tatattctga aagaaagata tttacaaaag aaaagaatga
     2401 atcacctaca atttatacag atagtgctaa agtagaaaat agctttatag catctggttg
     2461 tttaatagaa ggtactgtaa aagatagtat catatttaga aaggtaaatg ttgaaaaagg
     2521 aacagttata gagaactcaa tagtaatgca aaattgtgta ataaagtcaa atgcaaaact
     2581 atataatgca atattagata aaaatacaag tgtatcaaat gggaaagaat taagaggaga
     2641 tgaaaaatat cctcttgtag tggaaaagaa tacaaatata taaataaatt ttttagaagg
     2701 gggaatgact aatgaaggtt ttttatgtaa cagcagagtg ttggcccttt gcaaaaactg
     2761 gaggattagg agatgtttct tatgcattgc ctaaagaatt aaaaaaagaa ggtgtagatg
     2821 taagggtaat aatgcccaaa tattcaacta taccaagtta tttaaaagat caactaaaag
     2881 aaatagctgt gtttagtgta cgtgttggat ggagaaatca atactgtggt cttttagaaa
     2941 tggaattgga tggtgtaaaa ttttacttta tagataatga attttatttt agaagagaag
     3001 atgaaagaaa gagtatctat ggatatggag atgatgcaga aagatatact ttctttacag
     3061 atgcagtttt agaagctata agtagaattg atttttatcc agatgtaata catataaatg
     3121 attggcatac agggatgtta ccattaattc taaaagaaag atatgcaacc cttgaggggt
     3181 ataaaaatat aaaaactatg tatactatac ataatctcca atatcaaggt gtatttgata
     3241 agcatgtttt atatgatata ttggacttac cacaaaaata ctttgataat ggagatatag
     3301 agtattatgg ctcaataaat tttatgaaag ctggtataaa ttttgcagat aaaattataa
     3361 ctgttagtcc tacttatgca aatgaaatac aaacatcttt ttatggcgaa caattagatg
     3421 gattacttag aaaagagtca ggaaaattaa aaggtatatt aaatggtata gattatgatt
     3481 taaatgaccc tgcaaaagat aaagatatat ttgttcatta tgatgtagac tcaattgaca
     3541 aaaaagtaga aaataaattg agattacaag atatattggg actaaaaaaa gattcatcta
     3601 ttccgttgat aggtatagtt tcgagattag tttctcaaaa aggatttgat ttaatagcat
     3661 acatgatgcc agaacttatg agagaagatt tacagattgt cgttttagga actggagaac
     3721 atcaatatca atcaatgttc aactattacg attctaattt ttcagataaa gtatcagcta
     3781 gaattacttt taatgcatca ttggctcaac agatatatgc tgcaagtgat atgttcttaa
     3841 tgccatcatt atttgagcct tgtggtatag gtcaaatgtt agctatgaga tatggttctt
     3901 taccaatagt tagagagact ggagggctta gagatacagt aacaccttat aataaattta
     3961 ctggagaagg caatggattt agttttaaaa attacaatgc tcatgagatg tttttctgtt
     4021 tgaaaaatgc aatcaaagta tttaaggaca aagaaaaatg gattaaatta gttgaaaatg
     4081 caatgaaaac agataatagt tggaaaaaat cagctaagga gtatatagaa acatatagag
     4141 acatatgtga ttaaaggagt ggtttttttg gtaacaataa gcaaaaagaa attcaagcaa
     4201 aaatttgaag taaaaatgta tagcttatat gcacaatcta tcaaggaagc tactgatgaa
     4261 caattgttaa atgtattatg tagtctattg aaagatgaga tagcaaaaaa atgggttgct
     4321 acaaagttag ataagaaaaa agaagtttat tattttagtt tagaattttt aatagggaga
     4381 cagttaaaat ctaatttatt aaatttaaat attgaagaag aagttagaga aggtttatct
     4441 gaattaggaa tcaacttgga tgatttaatt gaagctgaag tagacccagc cttaggaaat
     4501 ggtggacttg gtagattagc agcttgcttt ttagattcta tggcatcttt gaacataagt
     4561 ggtcaaggat atggaataag gtataaatat ggtctgtttg aacaaaaatt tgtaaatggt
     4621 tatcaggtag aagtgcctga taactggctt acagaaggac gatatgcatg ggaaactgta
     4681 agaccaaatg aagcaacaat ggtgaagttt ggtggtgagg tagaattaat caaggaaggt
     4741 agtcatttaa aagtaattca taaaaactac cttcctgtaa tggcaatgcc ttatgatata
     4801 ccaataatcg gataccaaaa ccaatgtata aatactttaa gattgtttaa gagtgaaata
     4861 ccaaagagag attttggtga acttacctca aatgctctaa attattctgg tagctatgaa
     4921 gaggctttaa aacataagta ttatactgag gaaatatcac aggtattata tcctgatgat
     4981 tcaaactatg caggtaagtt gttgaggttg aaacaagaat acttttttgt aagtgcaggg
     5041 atacaagata taataagaaa atataaaaag aacaaattaa atattaataa tttattcgat
     5101 aaggtagcaa ttcatataaa tgatacacat cctaccttat gcataccaga acttatgaga
     5161 gttttgcttg atgaagaaaa tttatcttgg gatgaagcat gggaaataac taaaaaaaca
     5221 gtgtcctata ctaatcatac tataatgtca gaagcaatgg aaaaatggcc tgtaagtatg
     5281 atgaaagaac tattaccaag aatttatatg ataatagaag aaataaatag aagatatgta
     5341 gaggaattaa ataataaagg atatgaccaa gatagaataa aaagaatgag tataatagac
     5401 tgtgacaata tcaatatggc aaacttatgt attgtcacaa gtcatagtgt aaatggagtt
     5461 gctaagcttc atactcatat tcttgaaaca gaggtattaa aagatttcta tcaagatgaa
     5521 ccaaataaat ttaataataa gactaatgga attgcacata ggcgatggct tataagttca
     5581 aatcctcaac ttagcaattt aattacagat ttaattggtg attcatggaa gaaagataca
     5641 ttacaattaa aaaatattga aaaatttaaa aatgattcct ctgttttaca aagacttgat
     5701 gatataaaat acaataataa agcaaatcta gcaaagttta taaaagataa atacgattta
     5761 aatgtagacc caagttcgat atttgatgtt caagttaaga gattgcatgc gtataaaaga
     5821 cagttactga atatatttaa tgtacttcat atgtatcatg aattacttga taatcctaat
     5881 ttgaatcttg acccaagaac ttttatattt ggcgcaaaag cagcaccagg atattatttg
     5941 gctaaatgta taattaaatt tataaattct gttgcaagta ctataaataa tgatgttaga
     6001 gtaaaggaca agttaaaagt agtattttta gagaattatg gagtatcatt agcagaaata
     6061 ataataccag cagcaaatgt tagtgagcaa atttcaacta caactaagga agcatctgga
     6121 acaagtaata tgaagtttat gatgaatggt gctataactt tggctacact tgacggtgca
     6181 aatgtagaga tatgtgaaca ggttggtaaa gaaaatatgt ttttatttgg acttagtgca
     6241 gaacaagtac taaattataa taaatatggt ggatattctt cacttgacct atatcattct
     6301 aatatggata taaaaagggt agtagatgat ttaataaatg gatttattcc taatcttggc
     6361 gaagaaggaa gaagtattta taattcactc actacttaca atgatgagta ttttgtattg
     6421 agagattttg aaaattatgg tcaagctcaa gcagatataa acaggttata tagagataaa
     6481 gaaaaatgga ataaaatgtc tttagttaat atagctaatt ctggattttt ttcttctgat
     6541 agaacaattt ctgagtatgc aaaagacatt tggtttaaaa gggtgtgatt aaatgcaaag
     6601 tgtaatagaa tataactctt gggataaaaa ttttaaggct ccgtttggag ctttaaaatt
     6661 tgatgaggaa ttgaccattt gtgttaaagt aaatgaggga tacaatatca agtctatttc
     6721 cctagaaata aatagagaag aagaaatgag aacaataact ttaaatgaag aattagataa
     6781 tgataaactt ggaaagtgct tttgtggtaa gattgaaaag tttgatggta caggtgttta
     6841 tttttattac tttaaagttg atgttgaaat ggatggtcag ataaagactt tattttatgg
     6901 aaaaaacaga gataatggat attcttgtga atataattat agtgatatta ataaatatca
     6961 aatcactgtt tacaaagatt ttaaagtacc aacatggtac aaagaaggaa tactttatca
     7021 tatatttgta gatagattca ataatggaaa tcgtagtggt aaggttgata atcctaaaaa
     7081 aaatagtttc atatatggaa attgggaaga tacacctatg tacataaagg atagtcaagg
     7141 ggatgttata agatgggatt tccatggtgg aaatttaaga gggataatca ataaacttgg
     7201 atatttaaaa aaattaggtg taagtatact atatctaagc cctatatttg aagcctctag
     7261 taatcataag tatgatacag gtgactataa aaaaattgac ccaatgtttg gggatgaaga
     7321 tacatttaaa gaacttattg ataaagcaaa agaaaaaggt atatcaatag tattagatgg
     7381 agtttttagt catactggag cagatagtaa atattttaat atgtatggaa actataatag
     7441 tttaggggca tatcaatcta aagaatctcc atattattca tggtatatgt ttgaagaatt
     7501 tcctcaaaaa tataaaagtt ggtgggatgt taagacattg ccaaatataa atgaattaga
     7561 acatagctat atggattata taatatatga caatgatagc gttataaata aatgggtaaa
     7621 tatgggtatt aagggctgga gactagatgt tgcagacgaa ttaccaacta agtttataag
     7681 agagttaaaa aaggaattaa aaaaggcaga tgatgactca attcttatag gtgaagtatg
     7741 ggaagatgca tcaaataaga ttagctatgg tcagagaaga agttatttat taggtgaaga
     7801 attagattct gttatgggtt atccttttag aaataacatg ttttctttct taaaaggaga
     7861 aattaattca tatgaacttt gtaatagata tatgcagatt aaagaaaatt atccaaaaga
     7921 atcatttagg tctaatttaa atttaattgg aacacatgat gttacaagag ctaaaacgga
     7981 attaaatgat gatgtagatt tagtgaagct tgctgtagct atacagatga catttgaagg
     8041 agtaccatat atatattatg gagatgaagc aggtctttgt ggaggtgttg acccagataa
     8101 tagaagaact tatccatgga aaaatgaaga cgaagatatg cttaattttt atagagatgt
     8161 tataagaatt agaaataaga ataaactttt aagttctgga aatacagaat ttatatatac
     8221 taataatgat tctgtatttt cttttattag agttaatgaa aataatgata gaatgttaat
     8281 tttagtaaat agaagtgaaa atgtggaaag tatatcatta tgtatagaga gtagttttat
     8341 tgaggaaata cctataaagt atagtcttaa aaatgcaaat agtactatac aaattgaaaa
     8401 taatgagttg aaagtagatt tagactctaa atcatttaga atttttagag taaattaaat
     8461 atcttttttt agaaaaataa atagaaaata aggtgaatgt ggaaagagtt ttgttttatc
     8521 aaaacttttt ctactttttt tgtataaatt atcataagaa ttttagtatt tcaaaatatt
     8581 acaaagaagt ataaaaaata tcataattgt gatattatat aaattagtaa gataaaactg
     8641 aactctctac caaagttgta gggagattta acttttataa tcttaatatg gaggaacgtc
     8701 ttatgaaggt agatccactt acaactcaag tatatgacta tatatcaaag aaaatccaaa
     8761 atggagaata tgaagctaat cagagaatta ctgaatctga gatttgtaaa tctatcggag
     8821 ttagtagaac accagcgaga gaagcattaa ctaggttagc aggtgaaaat ttactagaaa
     8881 aaatacctaa taagggattt gtagtaaaag aatttcagga aaaggagaaa ttagacacct
     8941 attccgtaat tggagtattg gatgcgttag ccggttcttc agcattacaa aatttaactg
     9001 aatcagacct agtaaaaatg gaagaattaa cagaaatgat ggcggtctct ataaagtata
     9061 aaaattacaa tagctattta aaattaagta atgaatttca cgatatatac ataactaaat
     9121 cagataatca ggtgttagta aatctattga actctttaag atataatttt atgtcaaagt
     9181 catatactag tgataatgaa gatgagttat ataaaatgtt gacatacagc aataatcaac
     9241 atattgaagt agtaaaatct atgagggaga atgatttaga aaatgttgaa agaattttga
     9301 gagaacattg gaaaacgata cctatggaag agatgaaaaa agagaagctt ttataaagtt
     9361 tctctttatt ttttatacca ttttatcact atttttttga attattaagt agaaaataat
     9421 aattaattta aacttgagga ggaaaactaa tatgtatcca aataaagaaa ttgcaataga
     9481 agagttagaa gtggctggca aaatgaatcc cggtccatgg ataaaacatt cttacaatgt
     9541 tgctaatgta gctaaattga ttgcagagca atgtgaaaat ttgaatagtg aaaaggcctt
     9601 tgtatgtgga ttattacatg acattggaag aagaactggt atttcttctg taaggcatat
     9661 tattgatgga tatgattatg ttatttctaa gggatgggat gaagtggcga gggtatgttt
     9721 gacacattct tttcctgtta aggatataga agctgatatt ggaaataaag atattagtaa
     9781 agaacagtat gattttatca atcactattt aaacaacctt gaatataacg attatgataa
     9841 gttgattatt ctttgtgatg cattagcaga tgcaaatggg ttttgtattt tagaaaaaag
     9901 atttgttgat acaacacgaa gatatggaat atatccattt tcagttgaac gatggaataa
     9961 gacttatgag tataaagaat atttcgagaa aataatcaac aagtctatat atacattgtt
    10021 acccaatatt gaaaaatcta tatattatta aatcctaagt taataattta atatccagta
    10081 tcaccagcag ttggtcatta tgattgactg cttttattat gcttatatta aaaaaataca
    10141 ctatggtttg tgtatatcaa agttatatgg aatgaaaaga gaatttattt tatcaattaa
    10201 aaaatttaat aaattttata ttaaaattaa aatacaaaaa taggaaaatt atttagtcca
    10261 actaaaccaa gaattttgat atgtgaaata agaataatat aaaagtt
//
LOCUS       DAYAOO010000119        10257 bp    DNA     linear   BCT 12-OCT-2024
DEFINITION  TPA_asm: Clostridioides difficile isolate ST8-SSI-h139-18
            SAMN40601845-rid21577343.denovo.123, whole genome shotgun sequence.
ACCESSION   DAYAOO010000119 DAYAOO010000000
VERSION     DAYAOO010000119.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN40601845
            Sequence Read Archive: SRR28438827
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 10257)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10257)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-MAY-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-MAY-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002157583.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002157583.1
            Genome Coverage       :: 163x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/11/2024 16:19:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 4,038
            CDSs (total)                      :: 3,963
            Genes (coding)                    :: 3,930
            CDSs (with protein)               :: 3,930
            Genes (RNA)                       :: 75
            rRNAs                             :: 6, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 60
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 33
            CDSs (without protein)            :: 33
            Pseudo Genes (ambiguous residues) :: 0 of 33
            Pseudo Genes (frameshifted)       :: 7 of 33
            Pseudo Genes (incomplete)         :: 25 of 33
            Pseudo Genes (internal stop)      :: 11 of 33
            Pseudo Genes (multiple problems)  :: 8 of 33
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10257
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN40601845-rid21577343.denovo.123"
                     /isolate="ST8-SSI-h139-18"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Denmark"
                     /collection_date="2018"
                     /collected_by="Statens Serum Institute"
     gene            complement(40..1794)
                     /locus_tag="ACGI5H_003503"
     CDS             complement(40..1794)
                     /locus_tag="ACGI5H_003503"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall-binding protein Cwp23"
                     /protein_id="HFG9699190.1"
                     /translation="MYIMNKKFKKFSKKLSILILVLIMFLFNNLTANAQIKEDSIIGI
                     DRYETAGLIADRQTYDTVILVNGDKNLSDGLSSSGLAGAINAPILLTKKSEIPKATLN
                     RLDNKSLNVVKKVYIIGGYNTIENSVEKDIKRKGIQVERINGNNRIETSYNVAKKINE
                     VSSVKEVMLTNGFVGEADAMSIAPVVAKNKGAIILTDGKSVPFKTESLNVYAIGGKSA
                     INEDLVNETKATRIGGNDRFETNKKVMEKFYNGATDFYITNGYQLVDALTLSPLAKEK
                     PIVLVADGSNKGILKGAKSITKVGGIDANIYKQCLDMIKYNNMDMTPNILKHLTSVEG
                     NEVSEILIESDNLGVVVEKTNTNKFEFDYVSVTNEKNCTFSVYKENSSNNIKNGKLVV
                     SAKKKIDKKDSDLQDMNGDNMINANKDRMVNVIKIGVPDKMYSNFKVDVESGSVELYN
                     IKGGATVDVNDGIANIVDNNVTNPFNINTNSGISGVTAETISSEIKFRANNGIVNVTA
                     TNINGNISLFGSDNKGTFDGIFKLNLKKEPSNLHLKLIGNGINKLPEGWSKDYILGNG
                     QPIIEVKNNGINNISIGE"
     gene            complement(2012..2902)
                     /locus_tag="ACGI5H_003504"
     CDS             complement(2012..2902)
                     /locus_tag="ACGI5H_003504"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889757.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HFG9699191.1"
                     /translation="MAKLTLEHIKGNTYYIPLPTIVGVYVDGKDAILIDSGNNKDTAR
                     QVLRLLEEHNLNPKLIINTHSNADHIGGNAYLKNQTKCKIATTKIEGYFTENPILESA
                     FLYGGYPSKALKNKFLLAKESEVDYIIPSNGKIVDTELEAISLPGHYFEMIGVRTPDN
                     VLFVADSLTPENIITKYHFFFLLDIDSQFKTLEKLRMLEADFFVPSHSVKTTDIKSLI
                     NINKKKMEEIIDNIKKVCYEPVMIDEVIEKMCDLYNVKLDANQYVLVGSTIRSYITYL
                     YENNMVEYIFDGGKMMIKAV"
     gene            3051..3911
                     /locus_tag="ACGI5H_003505"
     CDS             3051..3911
                     /locus_tag="ACGI5H_003505"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430304.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HFG9699192.1"
                     /translation="MLLKKDRITFSEILILIVGCILMAISLNLFFNPHAIAAGGITGL
                     GVVLNSLFGVELWIVNLLLNVPLFIFAYKILSKKDCFKTVLGIIFLTIALKLTANMAT
                     LDITNDMYLAIISGSILMGVGQGLIFRINGSTGGTDLMALLLNKYFPTFSIPVLMGIV
                     DCVVVVLSGIVNRQVEIALYSTVALYILVKVSDLLIEGFNYSKSFTIISDLSKDISKK
                     IMEDLDRGATILKGEGAYTGENKNVLLVVVEKKEVVELKKLVKNVDPNAFIIITDIHE
                     ALGNGFKKIE"
     gene            4367..4933
                     /locus_tag="ACGI5H_003506"
     CDS             4367..4933
                     /locus_tag="ACGI5H_003506"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728615.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0006950 - response to stress [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TerD family protein"
                     /protein_id="HFG9699193.1"
                     /translation="MSVSLQKGQRVSLVKDNNPVKNLVVGLGWDMNKLGKKNYDLDAF
                     AIALTNQDKMNVRGDLVYFGNLKHPSKAIIHTGDNLTGKGEGDDEQIIVNLEDIPEYV
                     HKIVFGVSIYKAKKRDQDFGQINNSFIRLIDSNSKQELFKYNLQEDFSGKVTVLAGEI
                     YRRNEEWKFNALGIGQNEELRELINTYK"
     gene            4973..5554
                     /locus_tag="ACGI5H_003507"
     CDS             4973..5554
                     /locus_tag="ACGI5H_003507"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430302.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0006950 - response to stress [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TerD family protein"
                     /protein_id="HFG9699194.1"
                     /translation="MGITLAKGQKVSLTKSNPGLKKVIVGLGWDINKYDGGFDFDLDA
                     SAFLTGTDGKVTNDGDFIFYNNLKHASGAVEYMGDNRTGVGDGDDEQINVDLSKIPQN
                     IAKISFSVTINEAITRRQNFGQVENSYIRIYNEETNEELIKYELGEDFSIETAIVVAE
                     LYRHNGEWKFNALGSGFEDGLAGLCKNFGVNIG"
     gene            complement(5611..6528)
                     /locus_tag="ACGI5H_003508"
     CDS             complement(5611..6528)
                     /locus_tag="ACGI5H_003508"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423804.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HFG9699195.1"
                     /translation="MTIRSLEIFVKVAECGKMSEVARNMYITQSSVSQAISEIEKEYG
                     VKLFDRISKKLYLTEAGKKLLGYGRHLLAVNEEMNDCMKHCAKNIRIRVGATVTVGTC
                     VISPIMLELYKVNPLIEPEVFVEDTRLIAKKLLNSELDIAIVEGKIKHPDIVTKSIIN
                     DNLVLICSHKHEFYKRDSIKVSELSNQPLIMRELGSGTRAQLEKQLKELKIPMNIRWS
                     CYNSEAILRAVVDNFGIAVISELLIEDYLKKHLLWACDIEGINLHRTFDIAYHRSKFF
                     TENISAFFDISVEYGKKQARKKSRSVNSL"
     gene            6658..8289
                     /locus_tag="ACGI5H_003509"
     CDS             6658..8289
                     /locus_tag="ACGI5H_003509"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896946.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-dependent oxidoreductase"
                     /protein_id="HFG9699196.1"
                     /translation="MKVLIIGGVAAGTKTAAKIKREMGDNCSVTILNKGDDISYAGCG
                     LPYYVGKIIEDKSSLIVNTPESFSKLTGAEVRCGVEVTSIDRNAKQVTLKTLSTGEKE
                     NLSYDKLVIATGADPIKPPIPGIDLPGVFFMRTPNDAIKLRDSIENGIKRAVVIGGGF
                     IGLEIAENLSAMGIRVSVVDMAEHVMPGFDTDFAEYVENHMADKGIMIFTGDQVVGIE
                     GENKVEKLRTKNRAIKTDLVVMSVGIRPNTGFLKDTGLEFAPNNTIIADEYMLTNDKD
                     IYVVGDCAFVKNSLTNKPTWSPMGSSANHEGRICAQNISGKSKTYNGVLGTTVVKLPE
                     LNAGKTGLSKEIAEKEGYNVCSVTIATDDKAHYYPGASNFIIRMVAEKNTRKLLGVQV
                     MGPGAVDKIVDIAATAITLGADLYSLESMDLAYAPPFSTAIHPFVVAVNVLQNKLNGE
                     LDSVLLDEIEDFDSWTKLDVSKAPSIPSLRYIPVGEINGEIEGLAKDEKILLICAKGK
                     NSYMAQNRLRRFGYTNTKVLEGGILFYPNLKVMEE"
     gene            8292..9239
                     /locus_tag="ACGI5H_003510"
     CDS             8292..9239
                     /locus_tag="ACGI5H_003510"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423799.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4Fe-4S dicluster domain-containing protein"
                     /protein_id="HFG9699197.1"
                     /translation="MSNVTAEQKKEVKGRGFLPSRDGEHFAARIITVNGVINASQAKK
                     IAEAAEKFGNGQLAFTTRLTVELPGVKFEDIEALSEFIASENLITGGTGSRVRPVVAC
                     KGTVCVHGLANTQALAAEIHEEFYKNWYDVKLPHKFKIGVGGCPNNCIKPDLNDLGIV
                     GQRVPDYDSELCVGCKKCAVVEVCPVKAAKLTDKGKLEIDSNLCNNCGKCIESCNFDS
                     IEEKESGYKVYIGGKWGKSVRPGTQIDRLFSKEELMTLIEKAILLFREQGNTGERFGI
                     TIDRIGADKFIEMLLSDEVLERKEEILEALLHLTGGAVC"
     gene            complement(9524..9787)
                     /locus_tag="ACGI5H_003511"
     CDS             complement(9524..9787)
                     /locus_tag="ACGI5H_003511"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430298.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1883 domain-containing protein"
                     /protein_id="HFG9699198.1"
                     /translation="MEYSYSKMNLKKGDIVEVNLEKQANVILLDHINYVKFKNQRNYD
                     YYGGFAKKNPCRMRVPNTGTWYLVVNQDGNSGIVNFSINTIQN"
     gene            complement(9886..10131)
                     /locus_tag="ACGI5H_003512"
     CDS             complement(9886..10131)
                     /locus_tag="ACGI5H_003512"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423796.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9699199.1"
                     /translation="MFIDEELEGYILTCKISEDFKNIPEYSDEEFYVTVYKDESSDSG
                     YYALLENKEERVVWDGEVVANNIFNNLWIVVNKVKTG"
BASE COUNT         3582 a         1469 c         1420 g         3786 t
ORIGIN      
        1 taatttttaa aactatataa actttatttt catatgtttt tattctccaa ttgatatatt
       61 atttatgcca ttatttttaa cttcaataat tggttgtcca tttcctaaaa tataatcttt
      121 agaccaacct tctggcaatt tatttatccc atttccaatt aacttcaagt gtaaatttga
      181 tggttctttt ttcagattta atttaaatat tccatcaaag gtacctttat tatcgcttcc
      241 aaataaactt atattgccat ttatattcgt agctgttaca tttacaattc cattgtttgc
      301 tctaaatttt atttcagatg atatagtttc agctgttaca cctgaaatcc cactattagt
      361 atttatattg aaaggatttg ttacattgtt atcaacaatg ttagcaatcc cgtcattgac
      421 atcaacagta gctcctcctt taatattata aagttctact gaaccacttt caacatctac
      481 tttaaaatta gaatacattt tatcgggaac tccaattttt atcacattta ccatcctatc
      541 tttatttgca tttatcatat tgtcgccatt catatcttgc aaatcactat ctttcttatc
      601 tatttttttc ttagcactta caactagctt tccatttttt atattattag aagaattttc
      661 tttatataca gaaaaagtac aatttttttc attagttaca cttacgtaat caaactcaaa
      721 tttattggta ttcgtctttt caacaaccac acctaaatta tctgattcta taagtatttc
      781 agaaacttca tttccttcaa ctgaagttaa gtgttttaaa atatttggag tcatatccat
      841 attattatat ttaatcatat ctaaacactg tttatatata ttggcatcaa tacctccaac
      901 ttttgttata cttttagctc cttttaaaat acctttatta cttccatcag caactaaaac
      961 gattggtttt tctttggcta aaggagataa tgttagtgca tctactaatt gatatccatt
     1021 tgttatataa aaatctgtcg ctccattata aaacttttcc attacctttt tattggtctc
     1081 aaatctatca tttcctccga ttctagttgc tttagtttca tttactaaat cctcatttat
     1141 cgcagatttg ccacctatag cgtaaacatt taaactttca gtcttaaatg gaactgattt
     1201 cccatctgta agtattatag ctcctttatt ttttgcaact acaggtgcta tactcatagc
     1261 atcagcctct cctacaaatc catttgtaag cattacctct tttacactac ttacttcatt
     1321 tattttttta gctacattat aactagtttc aattctattg ttaccattta ttctttccac
     1381 ttgaatacct tttcttttta tatctttttc tactgaattt tcaatagtat tataaccacc
     1441 aattatatat acttttttta caacatttaa actcttatta tctagtctat ttaaagtagc
     1501 ttttggtatt tcactttttt tagtcaaaag tattggtgcg ttaatagctc cagctaatcc
     1561 acttgatgaa agcccatcag ataaattttt atctccatta actaatatta cagtatcata
     1621 agtttgtcta tctgctataa gtcctgctgt ttcatatcta tcaattccta ttattgaatc
     1681 ttctttaatc tgtgcatttg cagttaaatt attaaaaaga aacataatca aaactaaaat
     1741 taatatactt agttttttac tgaatttttt gaatttttta ttcataatat acactattcc
     1801 tcctgtaaat taaggtcttt aatttgctta taaattatcc ccttatttac aaataataac
     1861 ataatattat agtaacgtat atattacctt aaaattatca gtaactttat atcaatcatc
     1921 ttagcttatt tatataaatt tttttatatt acttttcaaa taacagtcat actaaaacaa
     1981 tttcatcata taatttgaaa attattacta tttacacagc ttttatcatc atcttaccac
     2041 catcaaatat atattcaacc atattattct catataaata agttatataa gaacgtattg
     2101 tacttccaac caacacatat tgattagcat caagcttgac attgtacaaa tcacacattt
     2161 tttcaataac ttcatcaatc ataactggct cataacaaac ctttttaata ttatctatta
     2221 tttcttccat cttcttctta ttaatattaa ttaaactttt tatatctgta gttttgacag
     2281 agtgacttgg aacaaagaaa tcagcctcta acattctcaa tttttctagt gtcttaaact
     2341 gtgaatctat atccagtagg aagaaaaaat gatatttagt aattatattc tctggtgtaa
     2401 gactatctgc aacaaacaaa acattatctg gagttctaac accaatcatt tcaaaataat
     2461 gacctggaag agaaatcgct tcaagttctg tatctacaat tttgccattt gaagggataa
     2521 tataatcaac ttcactttcc tttgctaata aaaatttatt cttcagtgct ttacttggat
     2581 agccaccata taaaaatgct gattctaata ttggattttc tgtaaaatat ccttcaattt
     2641 tagtcgtagc aatcttgcat tttgtttgat tcttcaaata tgcatttcct cctatatggt
     2701 ctgcatttga atgagtgttt attattaatt taggatttaa attatgttct tctaataatc
     2761 ttaaaacttg tctagctgta tccttattat ttccactgtc aattaaaatt gcatccttac
     2821 catctacgta tacacctact attgtaggga gtggaatata atatgtattt ccttttatat
     2881 gttctagagt taatttagcc attttataac ctccctttaa atttactttt aattatagca
     2941 ttaattttct gaaaattcca atcaaattgt ttttataata tatttttatt tcttttatta
     3001 aaaattggaa aaactatata atatatatta taatctatat ataaggagtg atgttattga
     3061 aaaaagatag aataactttt tcagaaattt taatattaat tgtaggctgt atattaatgg
     3121 ccatttctct taacttattt tttaatccac atgcaatcgc tgctggtggt ataacaggac
     3181 ttggagttgt tttaaattca ttattcggtg tagaactttg gattgtcaat ttacttttaa
     3241 atgttccatt attcatattt gcttacaaaa tactttcaaa aaaagattgt tttaaaacgg
     3301 ttttaggaat aatttttctt accatagcac ttaagcttac tgcaaatatg gctacattag
     3361 atataacaaa tgatatgtat cttgcaatta tatctggttc tattttaatg ggagttggtc
     3421 aaggacttat ttttagaata aatggctcta caggtggaac tgatttaatg gcactcctac
     3481 taaataaata ttttcctaca tttagtatac ctgttttaat gggtattgta gactgcgttg
     3541 tagttgtttt atcaggtata gtaaatagac aggttgaaat tgcactttat tcaactgtgg
     3601 ctttatacat tttagtaaaa gttagtgact tgcttattga aggatttaat tattccaaat
     3661 cattcactat tatatctgac ctttcaaaag atataagtaa aaaaataatg gaagatttag
     3721 atagaggtgc aactattcta aaaggagaag gtgcatatac tggagaaaat aaaaatgtac
     3781 ttttagtagt agttgaaaag aaagaagttg tcgaattgaa aaaattagta aaaaatgtcg
     3841 accctaatgc ttttattata attacagata tacatgaagc tttaggtaat ggatttaaaa
     3901 aaatagaata actaacaaat aaatagcaag tataattaac atatacaaat tcaacttttt
     3961 atatgttata ttatacttgc tatttatata ttatacttgc tatttatata ttataattgt
     4021 tgtttttaag ataaaaatta aatgtatcaa ttattgtttt atacaagtat ttccaaatcc
     4081 gttctcattt agatagtatg cttagaaatt ttagaattat tgagtctaac tttattactt
     4141 actttacttt ataacaatca aatacaaatt taaatattat aaaactacaa aataatttaa
     4201 agcatataat gtcaatatgt ttaaattata aaatattcat gtagttatat aataaataat
     4261 ttataaatat agccaactta gcctaaatac gtatataata tagctaatat ggttcttata
     4321 cttgatacca tcaataaaac taaaaatata aaaaggagaa cttaaaatga gtgttagttt
     4381 acaaaaagga caaagagtta gcttagtaaa agataataat cctgtaaaaa atctagtagt
     4441 aggcttagga tgggatatga ataaattggg taaaaaaaat tatgacctag atgcatttgc
     4501 aatagcattg actaaccaag ataaaatgaa tgttagaggt gacttggttt attttggaaa
     4561 tcttaaacac ccttctaaag ctattataca cactggagat aacttaactg gaaaaggtga
     4621 aggtgatgat gaacaaataa ttgttaattt agaagacata cctgaatatg tacataaaat
     4681 agtttttgga gtttctatat acaaagctaa aaaaagagac caggattttg gtcaaataaa
     4741 caactctttt ataagattaa ttgattcaaa ttccaagcaa gaattattta aatataatct
     4801 tcaagaagac ttttctggta aagtaacagt tttggcagga gaaatttatc gtagaaatga
     4861 agaatggaaa tttaatgctt taggaattgg tcaaaatgaa gagcttcgtg aattaattaa
     4921 tacatataag taataattac aataaaaaat ttataatgag gagttggttt aaatgggtat
     4981 aactttagca aaaggacaaa aagtaagttt aacaaaaagt aaccctggtc taaaaaaagt
     5041 aatagtagga ctaggatggg atattaataa atatgatggt ggctttgatt tcgatttaga
     5101 tgcctctgca tttttaactg gaactgatgg aaaagtaacg aatgatggag actttatatt
     5161 ctataataat ttaaaacacg cttctggagc tgttgaatat atgggtgata atagaacagg
     5221 tgttggtgat ggtgatgatg aacaaataaa tgtagactta tctaaaatac ctcaaaatat
     5281 tgctaaaata tcatttagtg ttactataaa tgaagcaatt acaagaagac aaaatttcgg
     5341 acaagttgaa aattcatata taagaatata taatgaagaa actaatgagg aacttattaa
     5401 atatgaattg ggtgaagatt ttagcataga aacagcaata gttgtggcag aactatatag
     5461 acataatgga gagtggaaat ttaatgcttt aggttctgga tttgaggatg gacttgcagg
     5521 attgtgtaaa aattttggcg ttaatatagg ctaatatatc taaataaaaa taagagtata
     5581 ttgatatact cttattttta tttagatata ttataaactg tttacacttc tactcttctt
     5641 tctcgcttgt tttttcccat attctactga aatatcaaaa aatgctgaaa tattttctgt
     5701 aaaaaacttg cttctatgat atgcaatatc aaatgtccta tgtaaattaa taccttcaat
     5761 atcacaagcc cacaaaagat gcttttttaa ataatcctca ataagtaatt cggatataac
     5821 tgcaatgcca aaattatcta caactgctct taatatagct tcagagttat aacatgacca
     5881 tctaatattc attgggattt ttaattcttt taattgcttt tctaattgtg ctcttgtacc
     5941 acttcccaat tcacgcataa ttaatggttg atttgaaagt tctgaaactt ttatagagtc
     6001 tcttttataa aactcatgct tgtgtgaaca tataagtaca agattatcat taataatgct
     6061 ttttgtaaca atatctgggt gcttaatttt tccttctaca atcgcaatat ctaattcact
     6121 attaagtaat ttttttgcaa tcagtcttgt atcttctaca aatacttcag gttctataag
     6181 aggatttacc ttgtataatt ctaacattat tggacttatt acacatgtac caacagttac
     6241 tgttgcccca actcttatac ggatattttt tgcacaatgc ttcatacaat cattcatttc
     6301 ttcatttaca gctaaaagat gcctcccata tccaagaagt tttttccctg cctcagttaa
     6361 atataatttt tttgaaattc tatcaaatag cttaacacca tactcttttt ctatttctga
     6421 aatagcttgg ctaactgatg actgggtaat atacatattt cttgctactt cactcatttt
     6481 accacattca gcaaccttaa caaagatttc aagactacga attgtcatat tatcacaacc
     6541 ttagcaaaca ttagtaaatg cttatgattt tattaatatt ttagtatttt acaaatatat
     6601 tgtcaagaag tataatttta ttatagagtt ataaagtaga ttggagtgtg atatattgtg
     6661 aaagtattaa ttataggtgg agttgctgct ggaacaaaaa ctgctgcaaa aataaaacgt
     6721 gaaatgggtg ataattgctc tgttacaata ctaaataaag gtgatgatat ttcttatgca
     6781 ggttgtggtc ttccatatta cgttggtaag ataattgaag ataaatcatc tttaatcgta
     6841 aatacacctg aaagtttttc taaactaaca ggagcagaag ttcgttgtgg agttgaagtt
     6901 acatctattg atagaaatgc aaaacaagta actttgaaaa cgctttcaac aggagaaaaa
     6961 gaaaatctaa gctatgacaa acttgtaatt gctacagggg cagacccaat aaaaccacca
     7021 atacctggaa tagatttacc tggagtattc tttatgcgta ctccaaatga tgctataaaa
     7081 ctaagagatt ctattgaaaa cggtattaag agagctgttg ttattggtgg aggtttcatt
     7141 ggtcttgaaa ttgctgaaaa tctttctgca atgggtatac gtgtaagtgt tgttgatatg
     7201 gctgaacatg ttatgcctgg atttgatact gattttgctg aatacgttga aaatcatatg
     7261 gctgataaag gcataatgat ttttacaggt gaccaggttg taggtattga aggtgaaaat
     7321 aaagttgaaa aacttcgtac taaaaataga gctattaaaa cagatttagt ggttatgtca
     7381 gttggaatcc gtcctaacac aggttttcta aaagacacag gtttagaatt tgcccctaat
     7441 aatacaatta ttgcagatga atatatgctt acaaatgaca aagatatata tgtagttgga
     7501 gactgtgctt ttgtaaaaaa ttctttaaca aataaaccta catggtcacc tatggggtca
     7561 tctgcaaatc atgagggtag aatttgcgca caaaatatat ctggaaaatc taaaacttac
     7621 aatggtgttc ttggaacaac agtagtaaaa ttacctgagc tcaatgcagg aaaaacaggt
     7681 ctaagtaaag aaatagctga aaaagaaggt tataatgttt gctctgtaac catagctact
     7741 gatgataaag ctcattatta tccaggtgca tctaatttta ttataagaat ggttgctgaa
     7801 aaaaatacta gaaaattatt aggtgttcaa gttatgggac ctggagcggt tgataaaata
     7861 gtagatatcg ctgctactgc aataacttta ggcgctgacc tttattcatt agaaagtatg
     7921 gaccttgcat atgcaccacc tttttcaaca gctattcacc cttttgtagt ggcagtaaat
     7981 gttttacaaa ataaacttaa tggagaactt gatagtgttt tacttgacga aattgaggat
     8041 tttgacagtt ggactaaact tgatgtttca aaagctcctt ctattcctag tttacgttat
     8101 attcctgttg gtgaaattaa tggagaaatt gaaggtcttg ctaaggatga aaaaattctt
     8161 cttatatgtg ctaaaggtaa aaatagctat atggcgcaaa atcgcttaag acgctttggc
     8221 tatacaaata cgaaagttct tgaaggtgga atactatttt atccaaatct taaggtaatg
     8281 gaggagtaaa tatgagtaat gttacagcag aacaaaaaaa ggaagtaaaa ggtagaggtt
     8341 ttctaccaag cagggatgga gaacattttg cagcacgtat aataactgta aatggtgtaa
     8401 taaatgcatc acaagcaaaa aaaattgcag aagctgctga aaaattcgga aacggtcagt
     8461 tagcatttac tactagacta acagtagaat tacctggtgt aaaatttgaa gatattgaag
     8521 ctctaagtga atttattgct agcgaaaatc taataacagg tggaactgga tcaagggttc
     8581 gtcctgttgt ggcttgtaaa ggtactgttt gtgttcatgg tctagctaat acacaggcac
     8641 ttgctgctga aatacatgaa gaattttaca aaaattggta tgatgtaaaa ctacctcata
     8701 agttcaaaat tggtgttggt ggatgcccta ataactgtat taaacctgac ctaaacgatc
     8761 ttggaattgt tggtcaacgt gtacctgact atgattcaga gctttgtgtt ggttgtaaaa
     8821 aatgtgctgt tgtagaggtc tgtcctgtta aagcagctaa attaacagat aaaggtaaac
     8881 ttgaaataga tagtaatcta tgtaataact gtggtaagtg tatagaaagt tgtaattttg
     8941 atagtattga agaaaaagaa tctggttata aagtctatat aggagggaaa tggggaaaat
     9001 cagttcgtcc tggaacacag attgatagat tattttcaaa agaggaactt atgactttaa
     9061 ttgaaaaagc aattctttta tttagagaac agggtaacac aggtgaacgt tttggaataa
     9121 ctatcgatag aatcggtgct gataaattta tagaaatgct tttatcagat gaagttttgg
     9181 aaagaaaaga agagatacta gaggctcttt tacaccttac aggtggagct gtatgctaac
     9241 aataaatatt ttaattgtac agataaccta tggaaaaaat tttagttaag aataattaaa
     9301 attctatata tgatatatga taaatgaggc tatctcaaaa cacagatacg cctctttttc
     9361 attgttgaaa tgataaagta tatttgagtt catataaaaa agagtgtctc atgaattata
     9421 aaattcattt tgaggcaccc acattatttt ataataattg cttattaatt ttattttaac
     9481 tatataaaat gtacaaaaat taagaatatc caatattcta aaattaattt tgaattgtat
     9541 tgattgaaaa gtttactatt ccactatttc catcttgatt tactactaga taccatgttc
     9601 cagtattagg aactctcatt ctacatggat ttttctttgc aaatccacca tagtaatcat
     9661 aatttctttg atttttaaat ttcacataat ttatatggtc taacaatatt acattggctt
     9721 gtttctctaa atttacctct acaatatccc ctttttttaa gttcatctta ctataactat
     9781 attccattga attactcctc cagtatcgaa taatctttgt tatttactca tctcaaatat
     9841 gtaaaaattc atttaaaata ttacaaatac tatataatta gactattatc cagttttaac
     9901 cttatttact acaatccaaa ggttattaaa aatattattg gcaacaactt ctccatccca
     9961 tacaactctt tcttctttat tttctaataa agcatagtac ccagagtcag aactttcatc
    10021 tttatagact gtaacataaa actcttcatc actatattca ggtatatttt taaagtcttc
    10081 agatatttta catgttaata tataaccttc taattcttca tctataaaca aagcaattcc
    10141 tccaatctct atatttttac taattatacc atattatgtc ataaactttt tattttatta
    10201 caaatttcta ttttttcttt actttataaa taaattatat aaattttaac ttttaaa
//
LOCUS       DAYAOO010000120        10148 bp    DNA     linear   BCT 12-OCT-2024
DEFINITION  TPA_asm: Clostridioides difficile isolate ST8-SSI-h139-18
            SAMN40601845-rid21577343.denovo.124, whole genome shotgun sequence.
ACCESSION   DAYAOO010000120 DAYAOO010000000
VERSION     DAYAOO010000120.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN40601845
            Sequence Read Archive: SRR28438827
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 10148)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10148)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-MAY-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-MAY-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002157583.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002157583.1
            Genome Coverage       :: 163x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/11/2024 16:19:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 4,038
            CDSs (total)                      :: 3,963
            Genes (coding)                    :: 3,930
            CDSs (with protein)               :: 3,930
            Genes (RNA)                       :: 75
            rRNAs                             :: 6, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 60
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 33
            CDSs (without protein)            :: 33
            Pseudo Genes (ambiguous residues) :: 0 of 33
            Pseudo Genes (frameshifted)       :: 7 of 33
            Pseudo Genes (incomplete)         :: 25 of 33
            Pseudo Genes (internal stop)      :: 11 of 33
            Pseudo Genes (multiple problems)  :: 8 of 33
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10148
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN40601845-rid21577343.denovo.124"
                     /isolate="ST8-SSI-h139-18"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Denmark"
                     /collection_date="2018"
                     /collected_by="Statens Serum Institute"
     gene            complement(548..1705)
                     /locus_tag="ACGI5H_003513"
     CDS             complement(548..1705)
                     /locus_tag="ACGI5H_003513"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425822.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S41 family peptidase"
                     /protein_id="HFG9699200.1"
                     /translation="MYLVISKKKAIFLGVILVIITAMVTSAFQLTLGNKVVISKELYE
                     DYKKYDKLLGLESIIKQDFYKKVSDTDLVNGAAKGLFLGTNDKYSGYYTKDEMENLIN
                     DSEGSYVGVGMYIGASKDGGLVVVPMKDSPAEKAGVKSGDKLVKVNGKSVSYKNSDEA
                     VRMMKGKKGKTVELTILREDKQLNFKVKTDQIIEKSIESKVIDNDLGYIEITQFISST
                     YTDFDKALKELKAKNIKGLVIDLRNNPGGMLDICKEVADELIGEGTIVYTKDNKGNTE
                     YLKSDKEKLGLPIVVLTNGESASAAEILTAAIVDNKEGISVGTTTFGKGLVQSVVRLK
                     DGTGYKLTTAQYFTPNGDYINEKGIKPTIEEKDENKQLDVATKWLREQIDK"
     gene            1859..2428
                     /locus_tag="ACGI5H_003514"
     CDS             1859..2428
                     /locus_tag="ACGI5H_003514"
                     /EC_number="6.3.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421346.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0030272 - 5-formyltetrahydrofolate
                     cyclo-ligase activity [Evidence IEA];
                     GO_process: GO:0006730 - one-carbon metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="5-formyltetrahydrofolate cyclo-ligase"
                     /protein_id="HFG9699201.1"
                     /translation="MKKEFRKKVIESRKNKSANFVLSNSNLITEKLLQMEDIRNATNI
                     MLYLNFNNEVQTDNLIKKLLSLKKIVSSPITIKENHTLIPTQITDLKEGLRIGAYGIR
                     EPNEKSPTIDIKALDVVIVPAVAYDIHCYRLGYGGGFYDRFLENLRKDAITIGIAFDF
                     QIFDSIPKETHDAQLDYIVTETRIITPNN"
     gene            complement(2610..3026)
                     /locus_tag="ACGI5H_003515"
     CDS             complement(2610..3026)
                     /locus_tag="ACGI5H_003515"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894025.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9699202.1"
                     /translation="MNVKFNIKGIIYGVIALVFVIGGFIFIPSMFVEKSKPIDYTVLQ
                     RNSIPEKILDVMDKYTNEERALAAKIDNKIYIIVTRGNNKYGIEMDKIESVVEEGKDV
                     LRVKIKYKDKEDSFPYIVVETNMSELPDRIELNATK"
     gene            complement(3252..4346)
                     /locus_tag="ACGI5H_003516"
     CDS             complement(3252..4346)
                     /locus_tag="ACGI5H_003516"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421350.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9699203.1"
                     /translation="MSEKVNVKTVISFAGAYVATVIGSGFATGQEIMQFFSFYGFAGI
                     IGGIISMVLFSWMGASVMSKGKELQLKEPIKIYRVYCGKYLGIFFEWFGPLFLFGVFV
                     VMISGAGATLTEYYGLNPFVGRVGMAVVALLTVSLGLDKLSKILGGIGPIIIIFTLLV
                     GGISLAKNIGNIGEAAQVLSTVKIAKPVPNAYLSGVIYTTYNTIVVMAFLTGLGASAA
                     NKKEAICGGILGGVALMAAAIMMHLAILSDIGNLYSKAIPSLFLADKISPVIGVLFSI
                     ILILGIYTTAVPLLWSVTNRFVDDKHPKFKLITLIAAILGLIGGFLPFDKLVGILYPY
                     TGYMGVIILVCVLYRQITKTSGYQEGISDK"
     gene            complement(4769..5710)
                     /locus_tag="ACGI5H_003517"
     CDS             complement(4769..5710)
                     /locus_tag="ACGI5H_003517"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transketolase family protein"
                     /protein_id="HFG9699204.1"
                     /translation="MSKMATREAYGKALVKLGQINDNVVVLDADLSKSTKTHDFYKSF
                     PDRFFNMGIAEQNLIGAACGLSTAGKIPFASTFAMFATGRAFEIIRNSVCYPKLNVKI
                     CATHAGLTVGEDGASHESVEDIAIMRAIPNMTVLVPADGVETEKIIFEIAKYNGPVYV
                     RLGRSSVPVLFDEDYKFEIGKGTVLREGKDVSIIACGIMVNEALLAQEKLQEEGISAR
                     VINMSSIKPIDKDLILESAKETNAIVTVEEHSIIGGLGSAVSEVVGESCPTIVKKVGI
                     KDTFGESGTPNELLKKYELTCDDIIKTVKEVIIAKRM"
     gene            complement(5703..6530)
                     /locus_tag="ACGI5H_003518"
     CDS             complement(5703..6530)
                     /locus_tag="ACGI5H_003518"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transketolase"
                     /protein_id="HFG9699205.1"
                     /translation="MRDHKGLNEIARIIRRDIVSMIHRAKSGHPGGSLSVVEILTALY
                     FDEMNVDSSNPKMEDRDRFVLSKGHAAPALYATLAEKGYFDKEELNGLRKIGRMLQGH
                     PDMKGTPGVEISTGSLGQGFSVACGMAMASKLDNAPWNVYTLLGDGEVQEGIVWEAAM
                     SAAHYKLDNLIAFLDNNGLQIDGDIESVMSLGSIVDKFKAFGWNVIEIDGHDFDQIFA
                     ALDIAKSTVKKPTMIVAKTIKGKGISFMENQAGWHGTAPSDEELEKALLELGGADNE"
     gene            complement(6701..7084)
                     /locus_tag="ACGI5H_003519"
     CDS             complement(6701..7084)
                     /locus_tag="ACGI5H_003519"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421356.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system PemK/MazF family
                     toxin"
                     /protein_id="HFG9699206.1"
                     /translation="MKGRLPKVSTNCEIKRGDLYYADLSPVVGSEQGGVRPVLIIQND
                     VGNKYSPTVIVSAITSQINKAKLPTHVEISSNEYGLNKDSVILLEQIRTIDKKRLREK
                     IGCLDENMMIKVDDGLQISLGLFTF"
     gene            complement(7053..7340)
                     /locus_tag="ACGI5H_003520"
     CDS             complement(7053..7340)
                     /locus_tag="ACGI5H_003520"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421359.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribbon-helix-helix protein, CopG family"
                     /protein_id="HFG9699207.1"
                     /translation="MYDKSKEKIEVTLPDSLISEVDSIVQMENSNREDFAKAAFQFYI
                     TQKKKIHIKESMKTGYREMGQINLSLAELGMTVEEVSSDDKNEGKIAQGEY"
     gene            complement(7373..8530)
                     /gene="alr"
                     /locus_tag="ACGI5H_003521"
     CDS             complement(7373..8530)
                     /gene="alr"
                     /locus_tag="ACGI5H_003521"
                     /EC_number="5.1.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903781.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008784 - alanine racemase activity
                     [Evidence IEA];
                     GO_process: GO:0006522 - alanine metabolic process
                     [Evidence IEA];
                     GO_process: GO:0009252 - peptidoglycan biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="alanine racemase"
                     /protein_id="HFG9699208.1"
                     /translation="MQKITVPTWAEINLDNLRFNLNNIKNLLEEDIKICGVIKADAYG
                     HGAVEVAKLLEKEKVDYLAVARTAEGIELRQNGITLPILNLGYTPDEAFEDSIKNKIT
                     MTVYSLETAQKINEIAKSLGEKACVHVKIDSGMTRIGFQPNEKSVQEIIELNKLEYID
                     LEGMFTHFATADEVSKEYTYKQANNYKFMSDKLDEAGVKIAIKHVSNSAAIMDCPDLR
                     LNMVRAGIILYGHYPSDDVFKDRLELRPAMKLKSKIGHIKQVEPGVGISYGLKYTTTG
                     KETIATVPIGYADGFTRIQKNPKVLIKGEVFDVVGRICMDQIMVRIDKDIDIKVGDEV
                     ILFGEGEVTAERIAKDLGTINYEVLCMISRRVDRVYMENNELVQINSYLLK"
     gene            complement(8545..9135)
                     /gene="gerS"
                     /locus_tag="ACGI5H_003522"
     CDS             complement(8545..9135)
                     /gene="gerS"
                     /locus_tag="ACGI5H_003522"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892025.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="germination lipoprotein GerS"
                     /protein_id="HFG9699209.1"
                     /translation="MRKKWTIVCIMFLALVIIVIGCQKRQSTKEEVYKDFQKQISDMN
                     YYSCKAEVEVVGNKSPHNYVLIHTYKKTDNYKLEVISPKHLKGKSIEYQDDKILVKNP
                     KISDVVELPNTGKNNQYLFVGDFIKNYLQNEEMKVKLSKGHLVLETFIPGDNKYFNKQ
                     VLYVNADTKNPEKMEVLDKEGVPRFTVKYKDFEYRN"
     gene            complement(9156..9617)
                     /locus_tag="ACGI5H_003523"
     CDS             complement(9156..9617)
                     /locus_tag="ACGI5H_003523"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421362.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CBS domain-containing protein"
                     /protein_id="HFG9699210.1"
                     /translation="MMDKTAKEIMTTDVIVAKQDDSIADVANMLIAEKIGGLPVVDSE
                     NRVVGIISETDILKKEKYIEAPLYINLLQGLIFLDDLKKVEKDIKQVAAYKVGELMSK
                     DIIKVHEDDKFDDVANVMIKKSINRVPVVDDDNKLKGIICRYDIIKALYNE"
     gene            complement(9632..10012)
                     /gene="acpS"
                     /locus_tag="ACGI5H_003524"
     CDS             complement(9632..10012)
                     /gene="acpS"
                     /locus_tag="ACGI5H_003524"
                     /EC_number="2.7.8.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861979.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008897 - holo-[acyl-carrier-protein]
                     synthase activity [Evidence IEA];
                     GO_process: GO:0008610 - lipid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="holo-ACP synthase"
                     /protein_id="HFG9699211.1"
                     /translation="MNIFDIGVDIIEIDRIRKAVDKNNRFLEKIFTDREIEYFNSKNF
                     KAESIAGNFAAKEAISKSIGTGIRLFNFKDIEVLRNEMGKPIVKTYNNLAKMCIDYNV
                     LEIKVSISHSKDYAIANAITIIKD"
BASE COUNT         3272 a         1870 c         1064 g         3942 t
ORIGIN      
        1 ttttataatt tcttcaaact atcataaaaa acattcacat gttttaggaa taaattatat
       61 aaaataggtt ataagataat gaacatttat attataacct atttttatat cgataagtat
      121 gaaattgttt aaccaagtca aaatgatata taaatttata tttaaatgtg tttagagttt
      181 aatttatttt caatgtttaa aaaagttatt ctatgcatct aatttaatta gtaaactgag
      241 gttctagtta gataaattat attataatga atatatagta tgcagtttac gatattttaa
      301 aagtaaatga tataatattt ggaacaactg ggttgcaatg tgtttttaaa aaatatcaaa
      361 ataaggctat gatttttaaa accatagccc tgtctgtaaa aatttaatta tcacttaaaa
      421 aataaatttt tatttaaaga atacacataa atatttccag actccctcat gaactaaaaa
      481 gttcattttg agacatctct tttataatgt tctttatttt atagtataag tttataaaaa
      541 ttaaatccta tttatcaatc tgttctctaa gccacttagt tgctacatct aactgtttat
      601 tttcatcttt ttcttcaata gtaggcttta tacctttttc attgatataa tctccattag
      661 gtgtaaaata ttgagcagta gttaacttgt atcctgttcc atccttcaat cttacaactg
      721 attgtaccaa ccctttacca aaagttgtag tccctacaga aataccttct ttattatcaa
      781 cgattgcagc tgttaatatt tcagcagcag aagcactttc tccattagtt aacactacta
      841 ttggaagtcc caatttttct ttatcagatt tcaagtactc agtatttccc ttattatctt
      901 ttgtatatac tatagttcct tcaccaatta actcatcagc aacttcttta catatatcta
      961 gcattccacc aggattattt ctaaggtcta ttactaatcc cttgatattt tttgctttta
     1021 attcttttaa agctttatca aagtcagtat atgtacttga tataaattgg gtaatttcta
     1081 tatatcctaa atcattatca attactttac tttctatact cttctcaatt atctggtctg
     1141 tttttacttt aaagttcaat tgtttatctt ctcttaatat agtcagttca actgttttac
     1201 cttttttacc cttcatcata cgaacagctt catctgaatt tttatatgag acagattttc
     1261 cattgacttt tactaattta tcccctgatt ttacacctgc tttctctgct ggagaatctt
     1321 tcatgggaac tactactaag ccaccatctt ttgatgcccc tatatacata cctacaccaa
     1381 cataagaacc ttcactatca ttaattagat tctccatttc atctttagta taataaccag
     1441 aatacttatc atttgttcct agaaatagac cttttgctgc tccatttacc aaatcagtat
     1501 ctgatacttt tttataaaaa tcttgtttta taatagattc tagtcctaac aacttatcat
     1561 attttttata gtcttcatag agttctttcg atattacaac tttattcccc aatgtcaact
     1621 gaaatgctga tgtaaccata gctgttataa ttactaaaat cacccctaaa aaaatagctt
     1681 tcttctttga aatcacaaga tacatctcct tttacataaa ctattattat tatatgacta
     1741 gctgttattt ttattacatt tacccaaata tattgcttta ttacaataaa ttatactaaa
     1801 atttatatta aatacaattg ctgtacacat tataacatat taagggagga attattttat
     1861 gaaaaaagaa tttagaaaaa aagttattga atcaagaaaa aataagagtg caaacttcgt
     1921 acttagtaat tcaaatttaa tcactgaaaa attacttcaa atggaagata taagaaatgc
     1981 aactaatata atgctttatc taaattttaa caatgaagtt caaacagata atttaatcaa
     2041 aaaacttttg tctctaaaga aaatagtatc aagtcccatc acaataaaag aaaatcatac
     2101 attaatccct actcaaataa cagatttaaa agagggattg agaattggag catatggaat
     2161 aagagaacct aacgaaaaat cacctacaat tgatattaag gccttagatg ttgtaattgt
     2221 accagctgta gcatatgata tacattgcta tagattagga tatggtggag gattttatga
     2281 tagattttta gaaaacttaa gaaaagatgc tataactatc ggcatagcat ttgacttcca
     2341 gatattcgat tctattccaa aagaaactca tgatgcacaa ttagactaca tagttactga
     2401 aactagaatt atcactccaa ataattagaa tattaagtat ttccagaccc catttaatat
     2461 agtaataaat actactgtta atatcttact ttataagcat tttaagtcat ggcttttaca
     2521 acaataagaa ccatatacaa tttacttaca ttaataaaaa ccatgacttt attgtacaat
     2581 atgcagttat ttaattataa aataccttct tatttcgtcg catttaattc tattctatct
     2641 ggaagttcac tcatatttgt ttcaacaact atgtatggaa aagaatcttc cttatcttta
     2701 tactttatct tgactctcaa aacatccttt ccttcctcaa ccacactttc tattttgtcc
     2761 atttctatac catatttatt atttcctcta gtcactataa tgtatatttt gttatcgatt
     2821 ttagccgcta atgctctttc ttcatttgta tacttatcca tcacatctaa tatcttttct
     2881 ggtattgaat ttctttgtaa tactgtataa tctatgggtt tagatttctc tacaaacata
     2941 cttggtatga atataaatcc ccctataacg aatacaagag ctataactcc ataaattata
     3001 cctttaatat taaactttac attcaatctt atcactcctc ccatatattc taaatatatg
     3061 atttataaac ttatcttaga ctctaaatta ttgattagta tatatttata cataattata
     3121 aatatatgta atgtaactaa aaaacatgtt ttttctattt cataataaac gagctaaaaa
     3181 ataaaaagag ctatatgaaa acattttcat tgttttcata tagctcttga gtttacaata
     3241 ttaaaaaata cttatttgtc actgattcct tcttgatatc cagatgtttt tgtaatctgt
     3301 ctataaagaa cacaaaccag tattatgacg cccatatatc cagtatatgg atataaaata
     3361 ccaaccagct tatcaaatgg taggaagcca cctataagac ctaatatagc tgctattaaa
     3421 gttattaatt taaacttagg atgtttatca tctacaaatc tattagttac tgaccataat
     3481 aaaggtacag ctgttgtata tatacctaat ataagaatta ttgagaataa aactccaatt
     3541 actggtgaaa tcttatctgc taagaataat gatggtattg cttttgaata taagtttcct
     3601 atatcagaaa gaatagctaa gtgcatcatt atagctgcag ccataagtgc tactccacct
     3661 aatataccac cacaaatagc ttcttttttg ttagcagcac ttgctcctaa tccagttaag
     3721 aatgccataa caacaattgt gttataagta gtatatatta caccagatag ataggcattt
     3781 ggaactggtt tagctatctt tacagtgcta agaacttgtg cagcttctcc tatattacct
     3841 atgtttttag ctaaacttat accaccaact aaaagtgtaa agattattat tataggccct
     3901 attccaccta gtatctttga taatttatca agacctagtg aaacagttaa taatgctact
     3961 actgccatac ctactctacc tacaaatgga tttaatccat agtattcagt taaagttgct
     4021 cctgctcctg aaatcattac tacgaaaaca ccaaataaga ataaaggtcc aaaccattca
     4081 aagaatattc ctaaatactt accacaataa acacgataaa ttttgatagg ttctttaagt
     4141 tgaagctctt taccttttga cataactgaa gcacccatcc atgagaataa taccattgaa
     4201 attatcccac caataatacc tgcaaaacca taaaaagaga agaattgcat tatttcctgt
     4261 cctgttgcaa atccagaacc gattactgtt gctacatacg cacctgcgaa actgatgact
     4321 gttttaacat ttactttttc tgacatatct cagttacctc cccatgtgaa attttttctt
     4381 ctgattaaac aattcgataa actacctaca atttccttta acataaaata catgataact
     4441 gttttatagc tttttagtat aataacttaa aacttataat ctgattttat accctactcc
     4501 tcctctcata atttttttag attcttttat ctaagtagtc attatatata aaattagttt
     4561 ctctataaat tatatattag tcatattttt ctgaatagtc aatatatatt tgaatatttt
     4621 ctctattttt gtaaaaattt gaatatttta ttacattttt gatatattga tatcatataa
     4681 aaaaaagaga gatataaatt aatataacac tttatacctc tcttttaaat atattatatt
     4741 attaacaaac atgaataatt tatatctctt acattctttt tgcaataata acttctttaa
     4801 cagtctttat tatgtcatca caagttaatt catatttttt taacaattca tttggagtac
     4861 cagattctcc aaatgtatct ttaattccaa ctttctttac aatggttgga caagactctc
     4921 ctactacctc acttacagca gaacctaatc ccccaattat gctatgttct tctacagtta
     4981 caatagcatt cgtttctttt gctgattcta atattaaatc tttgtctata ggttttatcg
     5041 aggacatgtt tataactcta gcacttatac cttcttcttg caacttttct tgtgctaata
     5101 gagcttcatt taccataatt ccacaagcta taattgatac atcctttcct tctcttaaga
     5161 ctgtaccttt tcctatttca aatttataat cttcatcaaa taaaactggt actgaacttc
     5221 tccctaatct aacataaaca ggtccattat acttagctat ttcaaaaata attttttctg
     5281 tttcaactcc atcagctgga acaagaactg tcatatttgg tatagctctc attatagcaa
     5341 tatcttccac actttcatga gatgctccat cctctccaac agtaagacct gcatgagtag
     5401 cacatatttt tacatttagc tttggataac aaactgaatt tcttataatc tcaaaagccc
     5461 ttcccgtagc aaacatagca aaagtacttg caaaaggtat tttaccagca gttgataatc
     5521 cacaagcagc gcctattaaa ttttgttcag ctatacccat attaaaaaat ctatctggaa
     5581 atgacttgta aaaatcatgt gtttttgtag actttgataa atctgcatct aatactacaa
     5641 cattgtcatt tatttgacct aattttacta atgctttacc atatgcttct ctcgtcgcca
     5701 ttttactcat tgtcagcacc tcctaattca agcaaagctt tttctagctc ctcatcactt
     5761 ggagctgtcc catgccatcc tgcttgattt tccataaaag atattccttt gccttttata
     5821 gtttttgcaa ctatcattgt aggtttttta actgttgatt tagctatatc aagagccgca
     5881 aatatttggt caaaatcatg tccatctatc tcaattacat tccaaccaaa agctttaaat
     5941 ttatcaacta ttgaacctaa actcattacg ctttctatat ctccatctat ttgaagtcca
     6001 ttattatcta aaaaagcaat taaattatca agtttataat gtgcagcact catagcagct
     6061 tcccaaacaa ttccttcttg aacctcacca tcaccaagca aagtatacac attccacgga
     6121 gcattatcca actttgatgc catagccata ccacatgcaa ctgaaaaacc ttgacctaaa
     6181 gaaccagtag atatttccac acctggcgtg cctttcatgt ctggatgacc ttgtaacatc
     6241 cttcctatct tccttaatcc attcagttct tccttatcaa aatagccttt ttcagccaat
     6301 gtagcatata atgctggtgc agcatgtcct tttgataata caaatctatc tctatcctcc
     6361 attttaggat ttgaagaatc cacattcatt tcatcaaagt ataacgcagt aagtatttca
     6421 actactgata atgaccctcc tggatgtcca gatttggctc tatgtatcat tgaaactata
     6481 tctcttctta tgatacgcgc aatctcattt aatcctttat ggtctctcat gcaattacct
     6541 cccttgagtt cgtaatttta tatcaattcc atattattat atcactttta tgctattttt
     6601 ttgcgttatt tttaatttta ttaacatagt acattaaaat taaaccttaa gagatattta
     6661 aaagaaaaaa gggattgtct aataaaagac aaatccctct ttaaaaagta aacaatccta
     6721 aacttatttg aagtccatca tctactttta tcatcatatt ttcatctaga caaccaattt
     6781 tttccctcag tctcttttta tcgatagttc taatttgctc taaaagaatt actgagtctt
     6841 tattaagccc atattcattg gaacttatct ctacatgagt aggtaatttg gctttattaa
     6901 tctgagatgt tatagctgat actataactg taggactata tttattacct acatcatttt
     6961 gtattatcag aacaggtcta acgcctccct gctctgaacc aacaactgga cttaaatcag
     7021 cgtaatataa atcaccacgc tttatttcac aattagtact caccttgggc aatcttccct
     7081 tcatttttat catcagaaga tacttcttca actgtcatac ctaattcagc tagtgacaga
     7141 ttaatttgac ccatttctct ataacccgtt ttcatagatt ctttaatatg aattttcttt
     7201 ttctgagtta tatagaactg aaaagcagct tttgcaaaat cttctctgtt actgttctcc
     7261 atctgaacta tactatcaac ttcagaaatc agagagtcag gtaaagtaac ttctattttt
     7321 tctttactct tatcgtacac aaaatcgcct cccagattat aatatcatgg ttttatttta
     7381 gcaaataact gtttatttgt acaagctcat tattttccat ataaacacgg tcaactcttc
     7441 ttgatatcat acataacact tcatagttta tagttcctaa gtctttagct atacgctcag
     7501 ctgtaacttc gccttctcca aatagtataa cctcatctcc aacttttatg tctatatctt
     7561 tgtcaattct aaccattatt tgatccatac atattctacc aactacatca aacacttctc
     7621 ccttaataag aacctttgga tttttttgga ttctagtaaa tccatctgcg tatcctattg
     7681 gaactgtagc tattgtttct ttacctgtag ttgtgtattt tagtccataa cttattccta
     7741 cacctggttc aacttgtttt atatgtccga tttttgattt taatttcatg gctggtctta
     7801 attctaatct atctttaaat acatcatcag atggataatg accatataat attattcctg
     7861 ctcttaccat atttaatctt aaatcagggc aatccataat agctgcactg tttgatacat
     7921 gttttatagc tatttttaca ccagcctcat ctaatttatc agacataaat ttataattat
     7981 tagcttgttt ataagtgtac tctttactta cttcatcagc tgtagcaaaa tgagtaaaca
     8041 taccttctaa atctatatat tctaatttat ttaattctat tatttcctgt actgacttct
     8101 cattaggttg gaaacctatt ctagtcatcc ctgagtctat tttaacatga acacaggctt
     8161 tttctcctaa agattttgca atttcattta tcttttgtgc tgtttctaaa gaataaactg
     8221 tcatagttat tttatttttt atagaatctt caaaagcttc gtctggagta tatcccaagt
     8281 tcaaaatagg aagtgttatg ccattttgtc taagttcaat tccttcagca gttcttgcta
     8341 ctgctaagta atctactttt tctttttcta gcaattttgc aacttctact gcaccatgtc
     8401 catatgcatc agcttttatt actccacaaa tcttaatatc ttcttctaat aaatttttaa
     8461 tattatttaa gttaaatctt aagttatcta gatttatctc tgcccatgta ggcactgtta
     8521 ttttttgcat gtctttagtc ccccttagtt tctgtattca aaatctttgt attttactgt
     8581 aaatcttggc actccctctt tatctaacac ttccattttt tcaggatttt ttgtgtcagc
     8641 atttacatat aatacttgct tgttaaaata tttattatcc ccaggaataa aagtctctaa
     8701 aaccaaatgt cctttggata actttacttt catctcctca ttttgaagat agttttttat
     8761 aaagtctcct acaaaaagat attgattatt ttttcctgta ttaggtaact ccactacatc
     8821 actaatcttt ggatttttaa ctaatatttt atcatcttga tattctatac ttttcccttt
     8881 taaatgtttt ggggaaatta cttctaattt atagttatcg gtttttttat aagtatgaat
     8941 taaaacataa ttgtgtgggc ttttatttcc aactacttct acttcagctt tacaactgta
     9001 ataattcata tcagaaatct gcttttgaaa atctttgtat acttcttctt ttgtggactg
     9061 tcgtttttgg catcctatta caattataac cagtgccaag aacataatac atactatggt
     9121 ccactttttt ctcacatcac acctcctact tcagtttatt cattgtataa agcttttatt
     9181 atatcatatc tacaaattat acctttaagt ttgttgtcat catctactac aggaactctg
     9241 tttattgatt ttttaatcat tacattagct acatcatcaa acttatcatc ttcatgaacc
     9301 tttattatat ctttagacat aagttctcca accttataag cagctacttg ttttatatct
     9361 ttttcaactt tttttaagtc atctaagaaa atcaatcctt gtaatagatt tatatagaga
     9421 ggtgcttcta tatatttttc ttttttaaga atatctgttt cagaaattat tccaacaact
     9481 ctattctctg aatctacaac tggcagacct cctatttttt ctgcaattag catattagct
     9541 acatctgcta tactatcatc ttgttttgct actattacat ctgttgtcat tatttctttt
     9601 gctgttttat ccatcataat gtaatcactc cttagtcctt aattatggtt atcgcatttg
     9661 ctatagcata atcttttgaa tgtgatattg aaacttttat ttctaaaaca ttataatcta
     9721 tgcacatttt tgctagatta ttataagttt ttactattgg ttttcccatt tcatttctga
     9781 gaacttctat atctttaaaa ttaaacaatc taattcctgt acctatagat ttacttatag
     9841 cttccttggc tgcgaaatta cctgctatac tttctgcttt aaaattctta gaattaaaat
     9901 actctatttc tctatctgta aatatcttct ccaaaaacct attatttttg tctacagcct
     9961 ttcttattct atcaatttca attatatcta cgccaatatc aaatatattc attgttcctc
    10021 cagaaaattt ataatacttc tttcaataat taataatgaa tttataaatt tactatcgat
    10081 aatacacatt attatttagt ttatgttact tatcttaatt taataatcat tataataaaa
    10141 ctgtaact
//
LOCUS       DAYAOO010000121        10027 bp    DNA     linear   BCT 12-OCT-2024
DEFINITION  TPA_asm: Clostridioides difficile isolate ST8-SSI-h139-18
            SAMN40601845-rid21577343.denovo.125, whole genome shotgun sequence.
ACCESSION   DAYAOO010000121 DAYAOO010000000
VERSION     DAYAOO010000121.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN40601845
            Sequence Read Archive: SRR28438827
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 10027)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10027)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-MAY-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-MAY-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002157583.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002157583.1
            Genome Coverage       :: 163x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/11/2024 16:19:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 4,038
            CDSs (total)                      :: 3,963
            Genes (coding)                    :: 3,930
            CDSs (with protein)               :: 3,930
            Genes (RNA)                       :: 75
            rRNAs                             :: 6, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 60
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 33
            CDSs (without protein)            :: 33
            Pseudo Genes (ambiguous residues) :: 0 of 33
            Pseudo Genes (frameshifted)       :: 7 of 33
            Pseudo Genes (incomplete)         :: 25 of 33
            Pseudo Genes (internal stop)      :: 11 of 33
            Pseudo Genes (multiple problems)  :: 8 of 33
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10027
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN40601845-rid21577343.denovo.125"
                     /isolate="ST8-SSI-h139-18"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Denmark"
                     /collection_date="2018"
                     /collected_by="Statens Serum Institute"
     gene            175..630
                     /locus_tag="ACGI5H_003525"
     CDS             175..630
                     /locus_tag="ACGI5H_003525"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419674.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9699212.1"
                     /translation="MGLRDKFAQSFARSKTMSGPEKKANEIMGKLLLKKAILPIVLMF
                     VIIIAGAMLKINSWVTLGINLVIAVGAFFYIRNSSKKYQNFKPYVGNLISLEKKGKKE
                     YVAIIKQGKLPVKLQIAYGGEDLEHVKKNQMVQISYNPDAKIAILVNRQ"
     gene            complement(851..1111)
                     /locus_tag="ACGI5H_003526"
     CDS             complement(851..1111)
                     /locus_tag="ACGI5H_003526"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438465.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9699213.1"
                     /translation="MDKLITELSSLGAIGILCALLFKNTMQEKKEDRDMYKKTVENFI
                     ELSTQQQEINKNILVQMGIMKTDVEEIKEDVTGIKGMLQNGV"
     gene            complement(1374..1727)
                     /locus_tag="ACGI5H_003527"
     CDS             complement(1374..1727)
                     /locus_tag="ACGI5H_003527"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CD1375 family protein"
                     /protein_id="HFG9699214.1"
                     /translation="MFKFDKNKIEQIKQGRKVEMQYKDISDISIGQVKQDDDITNNFI
                     ANAEIYEMLLNQSSVNEASNISSFSVRKSGGESGMVEVYVALILRGKKTIEEVPAVIR
                     EQVRIRCKELEIPVE"
     gene            complement(1744..7065)
                     /locus_tag="ACGI5H_003528"
     CDS             complement(1744..7065)
                     /locus_tag="ACGI5H_003528"
                     /inference="COORDINATES: protein motif:HMM:NF012632.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9699215.1"
                     /translation="MKRTKLLQRGNFFGDKNMVVDEFDEGYDNYDFINFFTGCCNYTF
                     GLKNNNILYGCGDNSNFQLGLGEDNTTRKLFTKIPNISTNIKKVACGESHAVILTSDG
                     ELLVAGINTDGQMGLGLEKVGKTVSTFEKVPEIKGVKDIACGLQSTYLLYNDGTLYVA
                     GNNLYGQLGLGTNGASANVNTFIKVDVDNVKAVFSYNKSAFIIKNDNKCYSTGFNNQG
                     QLGLGDKNNRDLFSLVSINDVKTIACGSEHTVLMTYNNDIYGCGKEKCFGNALQSSLF
                     TKIEEVNIKTIACGNGNTMLIDNKGILKVAGNNDIYQLGIANYSENIDNSFIDLKNIV
                     AKNIFIGLSHSILIDSNNDSYCTGDNTYGQLGSFFDDMHIVEFKKMDSEKYSYSNYIN
                     LIKSEDKLTLLKEEMEIKDIELPLDIHSVRDVVFSPYCTLVILGNGDVYGLGNNRYKG
                     MGSDLPSQLNELTKLSISNVKSIVASKNISGGIFYIKNDDTCYYSGPNSNSIAGVLPS
                     NSDIFKKISIDNVKKVVINTDLSNWFSLIVTNNKQIYTSGKSSSYVNGLSNKSASQYT
                     EIGVSNVTDAYSSYNATFIVADEKKVYATGINTNYLLGVNPNDGVNINLTLINNWFYV
                     NPSGASYSTNSCTNDITKINNIIIYEYMAILCTNYGSFLTGYHGTLWTKPSDSTYRVQ
                     QQGITHAGYISNYIYNYYPTRCTQSSYSTNFAYLYYGESTSNLKNVNPDNLLISGGSS
                     YIHQYGRNYLNNQSSNNIAASNINSGPITSDKAIFLYKALLYLSSNTLYGFGNISESA
                     KELDVSDTQDGYNATNYKKVMKNIKNIFIPPYDLSRDKTRFAILTDKSLFICGYNSKG
                     THGISVNSSLNLNNKINYNKKNSSSEISSNIQEIYSHSKSTYLLTNNNMLYSVGLNDV
                     GQLGVGDEINRKVFTKINIDNIKSINVNRFTDNSKHVFAIKNDNTCYAVGLNNSGQLG
                     IGDNVNRNVFTKINVENVKYVAVYGNTSLLLTNDGLLYGAGNNGKGQLGLGDTTSRNI
                     FTRIPINGVRDVYICNDVSIIVKNDNTCYVCGFVNGYFGFTEGSISTFTKINIENVKS
                     VVTAGSEATFFITNDNVIYTTGKKERVFFSTETNDIKGIRVINNIINAKKIVVNGYTS
                     AILTNDNKLFVGGLSGYGSIANNNNTNSVEDVKDVFVTANNTLYIDNNNNLISSGRDT
                     YGISDESYRDMSVPYYKVSIKKDVDTVFSSYNTIFIKDIYGKFYSSTGDNRYNHLGIH
                     HRYDNDKNEALEGSLHSYFKTDNTSDKIVFNKKNEKLVMFNDKYIKTNNKYINYKNIF
                     KDNFKYTSIILPFEVSDIDISKTHSLAVAKDGKLYGIGSNSYKEINQTLEDIELLTLT
                     EVNISDVKKVACGDNYSYIIKTDNTLWSYGKNTEYQLGVGHNNDVRELQKVTGLPSVK
                     DISIYNSMTLVLTNEGELYAQGYNTNGLFGLGESEKDKIIRTFTKVLTNVKEIKSHND
                     DHILVIKNDNSLWITGKNKSMYKISISITDLYEFTKIPIPEHLNDILDIELSDDTIYM
                     ITKVDTSKASIEIVEKSISQVRVVVQDPNNVIEKLEMFINDELISTKTNLEINSIIFE
                     IPQNKIVLGENKILIKASSPTGDLYSSMFIFKSETGLKVKKDSILMINNKVYSIINIT
                     ENNTDLIVTLNEGLKDDMMENNPIYQLINKTKVQVKINKSDLFKDMKLVEIKKSDSSY
                     QEIYELEEANIKSAQPKIIVEKGDKWTAIKRPSMIFRYDAESNEPQA"
     gene            complement(7082..8065)
                     /locus_tag="ACGI5H_003529"
     CDS             complement(7082..8065)
                     /locus_tag="ACGI5H_003529"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889153.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HFG9699216.1"
                     /translation="MEEKFYIILTKIGREKIANATALGELVGLTKFQVGDSNGEYYEP
                     TEEQTALKNVVWEGNINSLRIDEKNPNWIVIETILPGTVGGFMIREAAVLDNENNIIA
                     IGKYPETYKPRAEDGSIKDLVVKMILQLSNTSNVTLEVDPTLVFVTQKDIQDLDDKVD
                     KNIKEIKVKIGEELLSTEAKNLSGAINEVVEKIKNISIDDVIGGQIQTELSVLKNSYN
                     KLSEKVLDILIYLELESEIDVDEAGYWYDTLTNAKNIIAIEGLKLDLNRKCITGELGS
                     VTFKNVVLPFNANRVRYIHEMDNNFVETKSNRAYSIGQTDITLNKYSYEIR"
     gene            complement(8066..8764)
                     /locus_tag="ACGI5H_003530"
     CDS             complement(8066..8764)
                     /locus_tag="ACGI5H_003530"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428156.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative phage tail protein"
                     /protein_id="HFG9699217.1"
                     /translation="MKLIDKLPSFDRNYIVEEIQGAYDTELNILKEDIDDTFNQLFVD
                     TATWGLDMWEDILCIEKKELDFDTRRSNIKAKMRSRGTSTIEVIKSICEAYTKSETDI
                     KVYSDEFTFVLSFIANNCDYKTLLDCSDMIERVKPAHLLHYLEPIILDKSMVYCGGGM
                     VCSEEVKVHPYFEPIIKCSAVVNCGAGMLSREEIKVYPLSIKCIENNCKINIAIANDT
                     GVENVVVYPKSEVV"
     gene            complement(8761..9813)
                     /locus_tag="ACGI5H_003531"
     CDS             complement(8761..9813)
                     /locus_tag="ACGI5H_003531"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428158.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="baseplate J/gp47 family protein"
                     /protein_id="HFG9699218.1"
                     /translation="MYSDQTYEVIKNRTLENINLDIYKGEGSFLNNMVSGNNLELSKI
                     YLELSKIHKMAFIQDTYNQFLDKRVNEFGVYRKLGTESNGEVEFIGEKGTVINNGTII
                     SYRDLLFVVIKDVTIGSEEGDNSPVQALEVGKKYNLPTNCEFKLVDNISGVTKITNTR
                     SFEGGTDIETDEELKERFYKIQRNQATSGNKAHYEEWALEVDGVYNVKVYPRWDGPGT
                     VKVLIFGKNNQAVDTETIERCQQHIDEEKPIGPTITVVTPLPIEINISAVMKLEDGYT
                     LDNVKESFLESINTYFRDIRGEIIYTKVMGILINTTGVHDLSNLLINGSTDNITINED
                     KIPSVTTVNFSEVENQ"
     gene            complement(9806..>10027)
                     /locus_tag="ACGI5H_003532"
     CDS             complement(9806..>10027)
                     /locus_tag="ACGI5H_003532"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419656.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2634 domain-containing protein"
                     /protein_id="HFG9699219.1"
                     /translation="IYSLEYGTELSELIGQKYTKGLTESEASRFIKEALLINPYILEV
                     NVKSANFNRDVLSANVKVSTIYGEVEINV"
BASE COUNT         3189 a         1678 c         1043 g         4117 t
ORIGIN      
        1 tatttcattt attttctttt ttataatttt atgataaaat aattagtata ttttgcttta
       61 cttgaatgta attatttata caaaagtcaa acataatata aatgtagtaa atttttagtt
      121 tcaagtaata tctcgttatt ataactaaat atttattaaa attaggagga taaaatgggc
      181 ttaagagaca aattcgcgca atcatttgct agatcaaaaa ctatgagtgg ccctgagaaa
      241 aaggctaatg aaataatggg taaattgctt cttaagaaag ctatattacc tatcgtttta
      301 atgttcgtga taataatcgc tggagctatg cttaaaatca attcttgggt tacacttggc
      361 ataaatttag ttattgctgt tggtgctttc ttctacataa gaaattctag taaaaagtat
      421 cagaacttta aaccttatgt tggcaatttg attagtttag agaaaaaagg taaaaaagag
      481 tacgttgcta ttataaaaca aggtaagtta ccagttaagt tacaaatagc ttatggtggt
      541 gaagaccttg aacatgttaa gaaaaatcaa atggttcaaa taagttataa tccagatgct
      601 aaaatagcta ttttggttaa tagacaataa tttaataaaa aaaaggagtt gtcttaaaat
      661 tgattttttc taatcaaatt taagctcaac tcctttttta atttttatat attattttta
      721 tatattattt ttattacttt ttttaattaa tatttttaaa tatcaaatcc ttctcaataa
      781 aatagggtac tatctacaat actactttat cttttcctaa caatatataa tctggtgcta
      841 ctctttcatg ttatacaccg ttttgtaaca taccttttat accagtaaca tcttccttaa
      901 tttcctctac atctgttttc attataccca tttgaacaag tatatttttg tttatttctt
      961 gttgttgtgt agataattct ataaaatttt ctacagtttt tttatacatg tctctatctt
     1021 cttttttctc ctgcatagta tttttaaata atagagcaca tagtatacct attgccccta
     1081 gactactcaa ttcggttatt aatttatcca ttatagcctc ctattgtcta aattttttat
     1141 acttatagct ttaatttttg ttatattctt acatcatgca atattatatt ttcaggatta
     1201 tcaatttaat cttctgtact ttaaattgta ggtgcaattt atagattgaa taaataataa
     1261 atatatatac aatttctaat ataacaaaaa ataagtacaa ggcttactta ttaaagttaa
     1321 gaccttgtac tttacataaa aaaaataact aatacatagt tattctaaat ttactattca
     1381 actggtattt ctaattcttt gcatctaatt ctaacttgct ctctaattac tgctggtact
     1441 tcttctattg tttttttgcc tcttaaaatt aaagctacat atacttctac cattccactc
     1501 tcacctccag attttcttac actaaaagag cttatattac ttgcttcatt gacagaactt
     1561 tgatttaaca acatctcata tatttctgca tttgctataa aattatttgt tatatcatca
     1621 tcttgcttta cttgacctat acttatgtct gaaatgtctt tatactgcat ttctactttt
     1681 ctaccttgtt tgatttgttc tattttattt ttatcgaatt taaacaattt tcacacctcc
     1741 attttaagct tgtggctcgt tgctttcagc atcatatcta aaaatcatag atggacgttt
     1801 tatagctgtc catttatctc ctttttctac tatgatttta ggctgagcac tttttatgtt
     1861 ggcttcttct aattcataga tttcttggta acttgagtct gattttttga tttcaactag
     1921 tttcatgtct ttgaataagt cagatttatt tatttttact tgaactttag ttttatttat
     1981 taattgatat ataggattgt tttccatcat gtcatccttt aatccctcat ttaatgttac
     2041 tattaaatca gtgttatttt cagtaatgtt tatgattgaa tatactttat tgtttatcat
     2101 taaaatagaa tcctttttta ctttaagccc tgtttctgat ttaaatataa acatacttga
     2161 atataaatcg cctgtaggac tactggcttt aatcagtatc ttattttctc ctaatactat
     2221 tttattttgt ggtatctcaa atataatgct atttatttcc aaattagtct tagtagatat
     2281 taattcatca tttataaaca tttcaagttt ttctataaca ttattagggt cttgtactac
     2341 aactctcact tgagatattg atttttcaac tatttctata gatgctttac ttgtatctac
     2401 ttttgttatc atgtatattg tatcatctga aagctctata tctaaaatat catttagatg
     2461 ttcaggaatt ggtattttag taaattcata taaatcagta attgatatag atattttata
     2521 catagattta tttttaccag ttatccatag actattatca tttttaatta ctagtatgtg
     2581 gtcatcatta tgtgacttaa tttctttaac attagttaat actttagtaa aagttcttat
     2641 tatcttatct ttttcacttt ctcctagtcc aaataatcca tttgtattgt acccttgagc
     2701 gtacaactct ccctcattag ttaaaacaag tgtcattgag ttatatatac ttatatcttt
     2761 aacagaaggt aatccagtaa ccttttgtaa ctctcttaca tcattattgt ggccaactcc
     2821 caattggtac tcagtattct ttccatatga ccatagagta ttatctgtct taataatata
     2881 ggagtagtta tctccacaag caactttttt gacatctgat atatttactt cagtaagagt
     2941 taataattct atatcttcaa gggtttgatt aatttcttta tatgaattac ttcctattcc
     3001 atataacttg ccatccttag caacagccaa tgaatgtgtt tttgatatat caatatcaga
     3061 tacctcaaat ggcaatatta ttgaagtata cttaaaatta tctttaaata tgtttttata
     3121 atttatatac ttattatttg tttttatata cttatcatta aacattacta gcttttcatt
     3181 tttcttatta aaaactattt tatctgatgt gttatctgtt ttaaaatatg aatgtaggga
     3241 accttcaaga gcttcatttt tatcattatc atatctatgg tgaataccta aatgattata
     3301 tctattatct cctgttgaag aataaaattt tccatatata tctttaataa atatagtatt
     3361 gtaactagaa aatacagtat caacatcttt ctttatagat actttataat atggaactga
     3421 catatcccta taagattcat cagatatacc ataagtatct ctacctgatg atatcaaatt
     3481 gttattatta tctatataaa gtgtattatt agctgttaca aaaacatctt taacatcttc
     3541 cacactattt gtattattat tatttgctat acttccatat ccactaagac ctccaacaaa
     3601 tagtttattg tcatttgtta aaatggctga agtatatcca ttaactacta ttttttttgc
     3661 atttataata ttattaatta ctcgtatacc ctttatatca ttagtttctg ttgaaaagaa
     3721 taccctctct tttttccctg tagtataaat aacattgtca tttgttataa aaaatgtagc
     3781 ttcacttcct gctgttacaa cagattttac attctcaata tttatttttg taaatgtact
     3841 tatacttcct tcagtaaacc caaaatatcc atttacaaat ccacatacat aacatgtatt
     3901 atcattttta acaattattg atacatcatt acatatatac acatctctaa ctccatttat
     3961 aggtatacgt gtaaatatat tcctacttgt agtatcaccc aatcctaact gtccttttcc
     4021 attattacct gctccatata aaagaccatc attagttaat aatagagatg tgtttccata
     4081 tacagctaca tattttacat tttcaacatt tattttagta aatacatttc tatttacatt
     4141 atctcctatt cctaactgac cagaattatt taaaccaaca gcataacagg tattatcatt
     4201 ttttatcgca aatacatgtt tactattgtc agtaaatcta tttacattta tagattttat
     4261 attatcaata tttattttag taaatacctt tctatttatc tcatctccca ctcctaattg
     4321 acctacatca tttaaaccaa cactgtaaag catattatta ttagttaata aatatgtaga
     4381 cttcgaatgg ctatatattt cttgtatatt agaagatatt tcactactgc tattcttttt
     4441 attgtaattt atcttattat ttaaatttaa actactatta actgatatac catgcgtacc
     4501 cttagagtta tatccacata taaataagct cttatcagtt aatattgcaa atctagtttt
     4561 atctctactt aaatcataag gaggtataaa tatatttttt atatttttca ttaccttttt
     4621 ataattagtg gcattatatc catcttgtgt atctgaaaca tctagttctt ttgcactttc
     4681 agatatattc ccaaaaccat ataacgtgtt agaagataaa tacaatagag ctttatataa
     4741 aaatatggct ttatcagagg taataggacc tgaatttata ttagatgctg caatattatt
     4801 agatgattga ttgttaagat aattccttcc atattgatgt atataagatg aacctccaga
     4861 aataagtaaa ttatctggat ttacattttt taaattactt gttgattctc cataatacaa
     4921 ataggcaaaa tttgtagaat atgatgattg tgtacacctt gtgggataat agttatatat
     4981 gtaattacta atatatccag catgtgtaat tccttgttgt tgaactctat aagtagaatc
     5041 acttggcttt gtccataaag taccatggta tccagttaaa aaagaaccat aatttgtaca
     5101 taatatagcc atatattcat atataataat attattaatt ttagtaatat catttgtaca
     5161 agaatttgta ctataacttg ctcctgaagg atttacataa aaccagttat ttattaatgt
     5221 taaatttata ttgactccat cattaggatt aacacccaat aaatagtttg tatttatacc
     5281 agttgcatat accttttttt cgtcagccac aataaatgtt gcattatatg aactatatgc
     5341 atctgttaca ttgctaacac caatctcagt atattgactt gctgatttat tactaagtcc
     5401 attaacataa cttgaactct ttccagaagt atatatttgc ttattattag ttacaattaa
     5461 tgaaaaccag tttgataaat cagtatttat aacaactttt tttacattat ctatagatat
     5521 tttcttaaat atatctgaat tagaaggaag aacacctgct attgagttac tatttggccc
     5581 agaataataa caagtgtcat catttttaat gtagaatatt cctccagaaa tattttttga
     5641 tgctactata gactttacat tagagatact taattttgtc aactcattta attgacttgg
     5701 taagtcagaa cccattcctt tgtatctatt atttcctaga ccatatacat ctccattccc
     5761 taaaataacc agagtacaat aaggactaaa aacgacatct cttacagaat gtatatctag
     5821 tggaagttca atatccttta tttccatttc ttcttttaat aaagttaatt tatcctcaga
     5881 tttaattaaa tttatataat tactataact atatttttca ctatccattt tcttaaattc
     5941 tacaatgtgc atatcatcaa aaaacgaacc taattgtcca taagtattat ctcctgtaca
     6001 atatgaatca ttatttgaat caattagtat gctatgtgat aaaccaatga aaatattctt
     6061 agctacaata ttttttaaat ctataaatga attatctata ttctcagagt aatttgctat
     6121 acctaactga tatatatcat tatttccagc aaccttcaaa atacctttat tatctataag
     6181 catagtatta ccattaccac atgcaatagt ttttatattt acttcttcta tcttagtaaa
     6241 tagtgatgat tgaagtgcat ttccaaaaca tttttccttt ccacaaccat atatatcatt
     6301 attatacgtc attaacacag tgtgttcaga accacaagct atagtcttaa catcattaat
     6361 agaaactaag ctaaataaat ctctattatt cttatctcct aaacctagtt gaccttgatt
     6421 attaaaacca gtagaataac atttattgtc attctttatt ataaaagctg atttattata
     6481 tgagaataca gcctttacat tatcaacatc tacttttata aatgtattta catttgcaga
     6541 tgctccatta gttcctagac ctaattgacc atacaaatta tttccagcaa catataaagt
     6601 tccatcattg tataaaagat atgttgattg aagtccacat gcaatatcct ttacgccttt
     6661 tatttctgga accttctcaa atgtggaaac tgtttttcct actttttcta atcccaatcc
     6721 catttgacca tctgtattta tacctgcgac aagtaattct ccatctgaag taagtataac
     6781 tgcatgagat tctccacatg caactttttt aatattagta gatatatttg gtattttcgt
     6841 aaataatttt cttgttgtat tgtcttctcc caatccaagt tgaaagttac tattatctcc
     6901 acatccatac aagatattat tattttttag accaaatgta tagttacaac atccagtaaa
     6961 aaaattaata aagtcataat tatcataccc ttcatcaaat tcatcaacta ccatattttt
     7021 atcgccaaag aaattacctc tttgaagtag tttagttctt ttcattataa aaacctccta
     7081 attatcttat ttcatacgaa tatttattta aagttatatc tgtctggcca attgaatatg
     7141 ccctattaga ttttgtttca acaaagttat tatccatttc atgtatatat ctaactctat
     7201 ttgcattaaa tggtagaacc acattcttaa atgtaacact accaagttct ccagttatac
     7261 actttctatt taaatctaac ttaaggcctt ctatagctat tatgttttta gcattagtta
     7321 aggtatcata ccaatatcca gcttcatcta catctatttc tgactctaat tctaagtata
     7381 ttaaaatatc taatactttt tcagataatt tattgtaact attttttaat acagatagtt
     7441 cagtttgtat ttgacctcct attacatcat caatagatat atttttaatt ttttctacta
     7501 cctcatttat agctcctgat aagtttttag cttctgtaga taagagttct tctccaattt
     7561 ttacttttat ttcttttata tttttatcaa ccttatcatc taaatcttga atatcctttt
     7621 gagttacaaa aaccaacgtc gggtctactt ctaatgtaac atttgaagta ttggacaatt
     7681 gtaaaatcat ttttacaacc aaatctttaa tactgccatc ttcagcacgt ggcttatacg
     7741 tctctggata cttacctata gctattatat tattctcatt atccagaaca gcagcttctc
     7801 ttatcataaa tccaccaact gttcctggta aaatagtctc tataactatc caattaggat
     7861 ttttttcatc aattcttaga gaatttatat ttccttccca aactacattc tttaaagcag
     7921 tttgttcctc tgttggctca taatattctc cattactatc tccaacttga aacttggtta
     7981 atccaacaag ctctcctagt gcagttgcat ttgctatttt ttctctacca attttggtta
     8041 atattatata aaatttttct tccaattata ccacctccga tttaggataa actactacat
     8101 tttctacgcc tgtatcattt gcaatagcta tattaatctt acaattattt tcaatgcatt
     8161 taatgcttaa aggataaacc tttatttctt ctctacttaa cattccagct ccacagttta
     8221 caacagcgct acattttata attggttcaa agtatggatg aacttttact tcttcactac
     8281 ataccatacc tccaccacaa tagaccatac ttttatctag tattattggt tctaaatagt
     8341 gtaataagtg agcaggtttt actctttcaa tcatatcgct acaatctaaa agagttttat
     8401 agtcacaatt atttgctata aaactcaata cgaatgtaaa ttcatcacta taaactttta
     8461 tatctgtttc tgattttgta tatgcctcac atatactttt tataacttca atagtactag
     8521 tacctctgct tctcatttta gcttttatat tgctacgtct tgtgtcaaaa tcaagttctt
     8581 ttttttcaat gcagagtatg tcttcccaca tatctaatcc ccatgttgca gtgtcaacaa
     8641 ataattggtt aaaggtatca tcaatatctt ctttaagaat atttaattct gtatcgtatg
     8701 caccttgtat ctcctctaca atgtaatttc tatcaaatga tggtagttta tcaattagct
     8761 tcattgattt tccacctcac taaaattaac agttgttaca ctaggtattt tatcttcatt
     8821 aatagttata ttatctgtac ttccatttat aagtaggtta cttaaatcgt gtacaccagt
     8881 agtatttata agtattccca ttacttttgt atagattatc tctcctctaa tatctctaaa
     8941 gtatgtattt atactttcta ggaaagattc ttttacattg tctaatgtat atccatcttc
     9001 taatttcatt actgcactta tatttatttc tattggtaat ggtgtcacaa ctgttatagt
     9061 tggtccaata ggcttctctt catctatatg ttgctgacac ctttcaattg tttctgtatc
     9121 aacagcttga ttatttttcc caaatatcaa gaccttaact gttcccggac catcccatct
     9181 tggataaacc ttaacattat agactccatc tacttccaaa gcccattctt catagtgagc
     9241 tttatttcca cttgtagctt gatttctttg gattttataa aatctttctt ttagttcttc
     9301 atctgtctct atatctgtac caccttcaaa acttcttgtg ttagtaatct ttgttactcc
     9361 agatatatta tcaactagtt taaattcaca atttgtaggt aaattatatt tcttaccaac
     9421 ttccagagct tgaactgggc tattgtcacc ttcttcacta ccaatagtta catcttttat
     9481 tactacaaat agtaaatctc tatatgatat tattgtgcca ttatttatta cagttccttt
     9541 ctctccaata aattcaactt ctccatttga ctctgtacct aactttctat atacaccaaa
     9601 ttcattgact cttttatcga gaaactggtt atatgtgtct tgtataaaag ccattttatg
     9661 tatctttgaa agttctagat atatctttga aagttctaga ttatttccag ataccatgtt
     9721 gtttagaaaa gaaccttctc ctttataaat atcaagatta atattttcaa gagttctatt
     9781 ttttattact tcatatgtct ggtcactata catttatttc cacctcccca tagatagtgg
     9841 atacttttac atttgcactc aatacgtctc tgttaaagtt agcacttttt acgtttactt
     9901 ctaatatata tggatttatt agaagggcct cttttatgaa tctactagct tcactttctg
     9961 taagaccttt tgtatatttt tgtcctatta gttctgaaag ctctgtccca tattctaaag
    10021 agtatat
//
LOCUS       DAYAOO010000122         9665 bp    DNA     linear   BCT 12-OCT-2024
DEFINITION  TPA_asm: Clostridioides difficile isolate ST8-SSI-h139-18
            SAMN40601845-rid21577343.denovo.126, whole genome shotgun sequence.
ACCESSION   DAYAOO010000122 DAYAOO010000000
VERSION     DAYAOO010000122.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN40601845
            Sequence Read Archive: SRR28438827
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 9665)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9665)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-MAY-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-MAY-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002157583.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002157583.1
            Genome Coverage       :: 163x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/11/2024 16:19:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 4,038
            CDSs (total)                      :: 3,963
            Genes (coding)                    :: 3,930
            CDSs (with protein)               :: 3,930
            Genes (RNA)                       :: 75
            rRNAs                             :: 6, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 60
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 33
            CDSs (without protein)            :: 33
            Pseudo Genes (ambiguous residues) :: 0 of 33
            Pseudo Genes (frameshifted)       :: 7 of 33
            Pseudo Genes (incomplete)         :: 25 of 33
            Pseudo Genes (internal stop)      :: 11 of 33
            Pseudo Genes (multiple problems)  :: 8 of 33
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9665
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN40601845-rid21577343.denovo.126"
                     /isolate="ST8-SSI-h139-18"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Denmark"
                     /collection_date="2018"
                     /collected_by="Statens Serum Institute"
     gene            45..1235
                     /gene="dltD"
                     /locus_tag="ACGI5H_003533"
     CDS             45..1235
                     /gene="dltD"
                     /locus_tag="ACGI5H_003533"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426716.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0070394 - lipoteichoic acid metabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanyl-lipoteichoic acid biosynthesis protein
                     DltD"
                     /protein_id="HFG9699220.1"
                     /translation="MRKLIYFITPFIIGVVFLFGLDKFLDSKTDELLREKNLLPIMDD
                     TLSDIKDKGVTANNHFLREKDIMILGSSELSNSTKQHPKYYFNTNRSKNKVFAIGRAY
                     TQTLQDAAILGSMNPNIDNKKVVLLISMQWFMEKDGVTSHHYQSRFSPIQFYRFLDNP
                     KISKQNKIEYAKKSSKLLWGSDEYKAEALYAKLYEPKTFPEKAEKVLLEPYFQGRKYC
                     IALKEKGILYKRLIKLDKKRATKRKRPINWSYERKKAIEDAKKRVGKNPLNIDKYYYK
                     EHFKDGIEQYKGRDKDVNLLTSKEFENYKLMLNVCTDLGIKPVVVLIPSMDKFYNLTG
                     ISEKERNQYYDKAQKIAESKGFEVLNLKDKGSDKYYLRDVMHLGTKGWVDVCERLFKI
                     FKEQ"
     gene            1356..2870
                     /locus_tag="ACGI5H_003534"
     CDS             1356..2870
                     /locus_tag="ACGI5H_003534"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893738.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanine--poly(phosphoribitol) ligase"
                     /protein_id="HFG9699221.1"
                     /translation="MKIIEGIKKYSNTDRTALMCNGDKLSYKDLNEYSDAISVFLKDV
                     YKEEDTPIVIYGNKENMIMACMIGALKSGRAYVPLDISFPIDRVFEVTKEIKPKVLFN
                     FSDEKDFGDINVIDMDKLNYIINEYQGKSLDKENWVKDDENAYILFTSGSTGKPKGVQ
                     ISSNNLDSFSDWISPYLNIDGSEKVIMNQPAYSFDLSVTTIYPGLIHGATLFSISKDV
                     LADYKELFRQFSISDIAVWVSTPSFAGVCITEKEFNSKMLPNLESMIFIGEALSKNLT
                     KELMSRFPNTRIINGYGPTEATVGVSVNDMTQKAIDDEKSLPVGYPMSNCKIKILDED
                     GNELKENEKGEIIIIGPSVSKGYFNNKEKTDEVFFYDEIDGVKWRAYKTGDMGYLLDG
                     NIYYCGRKDFQIKLNGFRIEIEDIENNLRKVHNVKNAVVLPVYKDEKIAYLKGIVELN
                     EKNDLSNIKNGMIIKKELGKYIPSYMIPRNISIISEFPTNINGKIDRKKLMEEI"
     gene            2870..4018
                     /gene="dltB"
                     /locus_tag="ACGI5H_003535"
     CDS             2870..4018
                     /gene="dltB"
                     /locus_tag="ACGI5H_003535"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728953.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016746 - acyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0070395 - lipoteichoic acid biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanyl-lipoteichoic acid biosynthesis protein
                     DltB"
                     /protein_id="HFG9699222.1"
                     /translation="MIFSQYGDYFYLYILLLTSIPAVILGLMGKNIKYYGMLASLFMI
                     FLIVGIDVQLKYLVIFIILEVIIVKGYEYVRRKTKNKYIYWGFLFASMLPIIINKISP
                     VTSFGIIGFIGISYLNFRTIQMVIEIYDGAIKEVKISKMLYFMLFFPTLSSGPIDRSR
                     RFEQDLEKQISRKEYIEEYLLPGIKNIVMGVGYKFVIAFLINTYWVSRIPKDMSFINI
                     LSYMYAYSLYLFFDFAGYSLFAIGTGYIFGIQVPINFDKPFISKDMKEFWTRWHISLS
                     RWFGDYIFSRFVMSSMRKKRFKKRTTAAHVAQMITMITMGFWHGLTWYYVAYGVYQGL
                     ALVLTDIYQRKSKFYKKHKKDKWFERVQIFITFHIVCFGLLIFSGYLA"
     gene            4037..4267
                     /gene="dltC"
                     /locus_tag="ACGI5H_003536"
     CDS             4037..4267
                     /gene="dltC"
                     /locus_tag="ACGI5H_003536"
                     /EC_number="6.1.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861715.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0036370 - D-alanyl carrier activity
                     [Evidence IEA];
                     GO_process: GO:0019350 - teichoic acid biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanine--poly(phosphoribitol) ligase subunit
                     DltC"
                     /protein_id="HFG9699223.1"
                     /translation="MQETVIEIFEDVLGTDEIREDLDLNLFETELLDSLAIIEVLLEI
                     ENRLGIELQPTDLERKDMSTVNNLVKFLETRK"
     gene            4484..5269
                     /locus_tag="ACGI5H_003537"
     CDS             4484..5269
                     /locus_tag="ACGI5H_003537"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439571.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR family DNA-binding transcription
                     regulator"
                     /protein_id="HFG9699224.1"
                     /translation="MSLNSIDRKKEILKLLDSKGKVNTKELVKRLEVSSETIRRYLEE
                     LENENKLKKVYGGAIKINYGVIEPEHIKRNNTNLDKKQSIAKYAAKFVNDNESIIIDE
                     GTTNLQIVDYIISVNNLKIITNSYPVLSKLISYENQGLFDGEVIFIGGKVNLKHQRTA
                     CPMSIDTMKNLYVDKAFISSEGILDSFGISSIDQNKALLSKEYIKNSKESFVLCDSSK
                     IGIASMYKIADLEELDFVICDVEPPNEWKDKLNEINITWIEAK"
     gene            5548..7458
                     /gene="phnW"
                     /locus_tag="ACGI5H_003538"
     CDS             5548..7458
                     /gene="phnW"
                     /locus_tag="ACGI5H_003538"
                     /EC_number="2.6.1.37"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891151.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0047304 - 2-aminoethylphosphonate-pyruvate
                     transaminase activity [Evidence IEA];
                     GO_process: GO:0019700 - organic phosphonate catabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="2-aminoethylphosphonate--pyruvate transaminase"
                     /protein_id="HFG9699225.1"
                     /translation="MKKIYGEKIKAVVFDWAGTTVDYGCFAPLNVFIEIFKRRGIDVT
                     MEEARKPMGKLKIDHIREMCEMDRIKNIWSDKFGKVPTEDDVNELYAEFEPMLFETLE
                     EYTTPIPHVVETIEKLRKNGLKIGSTTGYTREMMNIVEPNAAKKGYSPDFLVTPSEVS
                     QGRPYPWMCYKNAEALGVSPMSSMVKVGDTISDVKEGVNAGMWSVAVIKGSSELGLTQ
                     EEVENMDKEELKAKMSIVSKKFKEAGAHFVIETMAELEDILIKIENETIKSDFVPEND
                     YILLTPGPLSTTKSVRASMLKDWCTWDVEYNNLVQDVRRRLVSLATQNTDKYTSVLMQ
                     GSGTFSVEAIIGSTISKDGKLLVIANGAYGKRMKDICNYLNIQFVDCTFKDIEAVDLN
                     VVENLLKENKDITHISMVHCETTTGRLNPIQEVGKLAKEYNKIYIVDAMSSFGGIEID
                     VEDFNIDFLVSSSNKCIQGVPGFGFIIANKEKLSKCKGIAKSLSLDVYAQWETMEKNN
                     GKWRFTSPTHVVRAFYQALLELEEEGSVEKRYARYKENQFTIASRLKSLGFDTLVNDN
                     AQSPVITTFLYPKNAKFEFMEFYTYLKDNGFVIYPGKLTDIDTFRIGSIGEVYPTDME
                     RLADVIEKFINR"
     gene            7817..8374
                     /locus_tag="ACGI5H_003539"
     CDS             7817..8374
                     /locus_tag="ACGI5H_003539"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9699226.1"
                     /translation="MNEELSSLRFDGVGKCKGGIFDNVNISGTGKIEGSVKCSKFDSS
                     GSAKVFGTTECNEFFTSGLSKVEGNILASKVEISGLLRCTGNINSVEIDTSGIINVEG
                     SIKSDIIHGEGYLKANENIDCENINLSGILECNGFLNCEEVNISLNGTSNFNEVGASS
                     INIKKGHGDYCKKFRMLEKKHISSR"
     gene            8467..8679
                     /locus_tag="ACGI5H_003540"
     CDS             8467..8679
                     /locus_tag="ACGI5H_003540"
                     /inference="COORDINATES: protein motif:HMM:NF024570.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4004 family protein"
                     /protein_id="HFG9699227.1"
                     /translation="MEELISKKDLLSKTNISYGQLYRWKRKNIIPEEWFIKKSAFTGQ
                     ETFFPRDKILERIELILSMKEETSLD"
     gene            9245..9652
                     /gene="tnpA"
                     /locus_tag="ACGI5H_003541"
     CDS             9245..9652
                     /gene="tnpA"
                     /locus_tag="ACGI5H_003541"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_045009167.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="IS200/IS605 family transposase"
                     /protein_id="HFG9699228.1"
                     /translation="MEVTHGRGYVYLVQYHIVWCVKYRHPVLTNEIEEDLINILNKIA
                     EDNKFQILECNSDKDHIHLLINCSPQHYIPDIIKALKGVSARLLMKKHGEQLKKKLWG
                     GHLWNPSYFVATVSENTEEQIRKYINNQKKQVK"
BASE COUNT         3928 a          969 c         1762 g         3006 t
ORIGIN      
        1 attaataata acataaattt gaatattttt agaggagaga aaatatgaga aaattgatat
       61 actttattac accttttata ataggcgtag tatttttatt tgggttagac aaatttcttg
      121 attctaaaac tgatgaactt ttgagggaga aaaatctact tccaattatg gatgatactt
      181 taagtgatat aaaagataaa ggggttacag caaataatca ttttttaaga gaaaaggata
      241 ttatgatttt ggggtcatca gaacttagta attcaacaaa acaacatcca aagtactatt
      301 ttaatacaaa taggagtaaa aataaggtgt ttgcaattgg gagagcctat actcagacat
      361 tacaagatgc tgcaatatta ggaagtatga atcctaatat tgataataag aaagttgtct
      421 tgttaatttc tatgcaatgg tttatggaaa aagacggagt cacaagtcac cattatcagt
      481 ctagattttc accaatacaa ttttatcgat ttttagataa tccaaaaata tctaaacaaa
      541 ataagattga atatgcaaaa aaatcaagta agttattatg gggaagtgac gagtataaag
      601 cagaagcatt atatgctaag ctatatgagc ctaagacatt tcctgaaaaa gctgaaaagg
      661 tgcttttaga gccttatttt caaggaagaa agtattgtat agctcttaaa gaaaagggta
      721 ttctttataa acgattaatt aagctagata aaaagagagc aacaaaaaga aaaagaccaa
      781 taaattggtc atatgagaga aagaaagcca ttgaagatgc taaaaaaaga gttggtaaaa
      841 atccactaaa tattgataag tactattata aagagcattt taaagatggt atagagcaat
      901 acaaaggaag agacaaagat gtaaatttat taacatctaa ggagtttgaa aattataaac
      961 tgatgctaaa tgtatgtact gacttaggta ttaagccagt tgttgtatta atcccaagta
     1021 tggataaatt ctataatttg actggtattt ctgaaaaaga aagaaatcag tactacgata
     1081 aagcacaaaa aatagcagaa agcaaaggct ttgaagttct aaaccttaaa gataaagggt
     1141 cagataagta ttatttaagg gatgtaatgc atcttggtac gaaaggatgg gtagatgtct
     1201 gtgagagatt atttaaaata tttaaagaac aataaagatt tgttaactag tatttgttta
     1261 actatggtta taatattggc gataggagtt ctaacattta ctccatttaa agaattgcca
     1321 tttatttata acggatttta aaggagcatt cttatatgaa aattattgaa ggaataaaaa
     1381 aatattcaaa tacagataga acagcactaa tgtgtaatgg agataaactt tcttataaag
     1441 atttaaatga atattcagat gctatatcag tatttctaaa ggatgtatac aaagaagaag
     1501 atactcctat agtaatttat ggaaataaag aaaacatgat aatggcatgt atgataggag
     1561 ctttaaaatc aggtagagcg tatgtgcctc ttgatattag ttttccaatt gatagagttt
     1621 ttgaagtcac taaagagata aaaccaaagg tattatttaa ctttagtgat gaaaaagatt
     1681 ttggagatat caatgtaatt gatatggata aattaaatta tataataaat gaatatcagg
     1741 gaaaatcatt agataaagaa aactgggtaa aagatgatga aaatgcatat atactattta
     1801 cttcaggaag tacaggaaag ccaaaagggg ttcaaataag ttcaaacaat ttagatagct
     1861 tttcagattg gataagccca tatctaaaca tagatggaag tgaaaaagta ataatgaacc
     1921 aaccagcata ttcttttgac ctttcagtta caacaatata ccctggtctt atccatggag
     1981 ctacattatt ttcaatatca aaagatgtat tagcagacta taaagaacta tttagacaat
     2041 ttagtatctc agatatagct gtatgggtgt caactccttc ttttgcagga gtatgtataa
     2101 ctgaaaaaga gtttaatagt aaaatgcttc ctaaccttga gtcaatgata ttcataggag
     2161 aagcactttc aaaaaatctt actaaagaac ttatgagtag atttccaaac acaagaatta
     2221 tcaatggata tggaccaacc gaggctactg ttggtgtaag tgtaaatgat atgactcaaa
     2281 aggctataga tgatgaaaaa agtcttccag ttggataccc tatgtcaaat tgtaaaataa
     2341 aaatacttga tgaagatgga aatgagctta aagaaaatga aaagggtgaa attataataa
     2401 ttggaccatc agtttctaaa ggttacttca ataataaaga aaagactgat gaagtatttt
     2461 tctatgatga aatagatggt gtaaagtgga gagcttataa aactggagat atgggatatc
     2521 ttttagatgg aaatatatat tattgtggaa gaaaagattt tcagattaaa ttaaatggat
     2581 ttagaattga aatagaagat atagaaaata atttgagaaa agtacataat gtaaaaaatg
     2641 cagtagtttt accagtatat aaggacgaaa aaattgctta cttaaaaggt attgttgagt
     2701 taaatgaaaa gaatgattta agtaatatta aaaatgggat gataataaaa aaggaacttg
     2761 gaaagtatat accttcatat atgattccaa gaaatatttc aataatctct gagtttccaa
     2821 caaatatcaa tggtaaaata gacagaaaga aacttatgga ggaaatttaa tgattttttc
     2881 acaatatgga gattattttt atctttatat attattatta acatcaatac cagcagtaat
     2941 tttaggtcta atgggcaaga atataaagta ttatggtatg ttggcaagtt tgtttatgat
     3001 attcttaata gtaggaattg atgtccaact aaagtacttg gtaatattta ttattcttga
     3061 agtaataata gttaaaggat atgaatatgt aagaagaaaa actaaaaata aatacatata
     3121 ttggggattc ttgtttgcat caatgctccc aataataata aataaaatat ctccagttac
     3181 ttcttttgga ataattggat ttattggaat atcatactta aatttcagaa ctatacaaat
     3241 ggttattgaa atttatgatg gagctataaa agaagttaaa atttcaaaga tgctttattt
     3301 tatgttattt tttccaactt taagttctgg acctattgat aggtcaagaa gatttgaaca
     3361 ggacttggaa aaacaaatct ctagaaaaga gtatatagaa gaatacttac tgccaggaat
     3421 aaaaaatatt gtcatgggag taggttataa gtttgttata gcatttttga taaatacata
     3481 ttgggtatca agaataccta aagatatgag ttttataaat attttaagtt atatgtacgc
     3541 atatagttta tacctgttct ttgattttgc aggatatagt ttatttgcta taggtacagg
     3601 atacatattt ggaatacaag tacctataaa ctttgacaag ccatttatca gtaaagatat
     3661 gaaagagttc tggacaagat ggcatataag tctttcaaga tggtttggag attatatttt
     3721 ttctagattt gttatgtcat caatgagaaa gaaaagattt aagaaaagga ctactgctgc
     3781 tcatgtggct cagatgataa ccatgataac aatgggattt tggcatggtc taacttggta
     3841 ttatgttgct tatggtgtat accaaggatt ggcacttgtg ttaactgata tatatcagcg
     3901 aaaatctaaa ttttataaaa aacataaaaa agataaatgg ttcgagagag tgcagatttt
     3961 cattacattc catattgtgt gttttggatt gctgatattc tcaggttatt tagcttaatt
     4021 ttaaggagga aaatttatgc aagaaacagt tatagaaata tttgaagatg tattagggac
     4081 tgatgagata agagaagatt tagaccttaa tttatttgag acggaacttt tagactcatt
     4141 agctataatt gaagttttac ttgaaattga aaatagatta gggatagagc ttcaaccaac
     4201 tgatttagag agaaaagata tgtctactgt aaataattta gtaaaattct tggagacaag
     4261 aaaataaatt agtagttaga ctttaaatat taatttataa aataaaattt tacaaagtcc
     4321 atctgatact aatatttgat ggactttttt aatgataata caaagtcttt tgaaaataac
     4381 tttaattaag taaaaaattt aatacataaa tatgatttca taaatcttag gtatcattgt
     4441 aatattatag gagaaaaata tattatattt aggaggaaaa tgaatgtctt taaattcgat
     4501 agatagaaaa aaagaaatac ttaaattatt agattcaaaa gggaaggtaa acactaaaga
     4561 attagtaaaa agattagaag tatcatcaga aacaataaga agatatttgg aagaattaga
     4621 aaatgaaaat aaattaaaaa aggtatatgg tggtgctata aaaataaatt atggagtgat
     4681 tgaaccagaa catataaaga gaaacaatac taacctagat aaaaagcaaa gtattgctaa
     4741 atatgcagct aagtttgtaa atgacaatga gtcaattatc atagatgaag gtactaccaa
     4801 tttgcagatt gtagattata taatatctgt aaacaattta aaaattatta caaactctta
     4861 tccagttcta tcaaaattga tttcttatga gaatcaaggt ttgtttgatg gagaagttat
     4921 atttattggt ggaaaagtaa atttaaaaca ccaaaggaca gcatgtccaa tgtcaataga
     4981 tactatgaaa aacttatacg tagataaagc ttttatatct agtgaaggta tacttgatag
     5041 ttttggaatt agtagtatag accaaaataa ggcattgttg tcaaaagaat atataaaaaa
     5101 ttcaaaggaa agttttgtat tatgtgatag ttctaaaata ggaattgcta gtatgtataa
     5161 gatagcagat ttagaggaat tagattttgt tatttgtgat gtagaacctc cgaatgaatg
     5221 gaaggataag ttaaatgaga taaatataac atggatagaa gcaaaataaa cccttagttt
     5281 tatataatac aactatgctc aatacaacta aattcataaa atatagtcag ttcatagatt
     5341 aagattagaa agtaaatttt agattgtaac ttaggatttt atgggaatat gatacaaaat
     5401 aaaaacaact aaatacaact aaaaacagaa atttaatata tatttaacct aaatatgatg
     5461 tataattaac atatgaaagt tatactttaa aagtaaaaac aattaaaaac acaaaaattc
     5521 taaaaagaat ctatggaggc tataaatatg aaaaagatat atggagaaaa aataaaagca
     5581 gtagtattcg attgggctgg aacaacagta gattatggat gttttgcacc tcttaatgta
     5641 tttatagaga tatttaaaag aagaggtata gatgtaacaa tggaagaagc aagaaaacct
     5701 atgggaaaat taaaaataga ccatataaga gaaatgtgtg aaatggatag aataaagaat
     5761 atttggtcag ataagtttgg taaagtgcca actgaagatg atgtaaatga actttatgct
     5821 gaatttgagc caatgttatt tgagacatta gaagagtata cgactccaat tcctcatgtt
     5881 gttgaaacta ttgaaaagtt gagaaaaaat ggattaaaaa taggttctac aacgggttat
     5941 acaagagaga tgatgaacat agttgaacca aatgcagcaa agaaaggata ctcacccgat
     6001 tttcttgtaa caccatcaga agtatctcaa ggaagaccgt atccttggat gtgctataaa
     6061 aatgctgaag ctttaggggt gtctcctatg agttctatgg taaaagtagg agatacaata
     6121 agtgatgtaa aagaaggcgt aaatgcagga atgtggagtg ttgctgtaat aaaaggttca
     6181 agtgagttag ggcttacaca agaagaagta gagaacatgg ataaggaaga attaaaagct
     6241 aagatgagta tagtttcaaa gaaatttaaa gaggcaggtg cacattttgt aatagaaact
     6301 atggctgagt tagaagatat actaataaaa atagagaatg aaactattaa atcagatttt
     6361 gtaccagaaa atgattacat attacttaca ccaggaccac tatctactac taaatcagta
     6421 agagcatcta tgttaaaaga ttggtgtact tgggatgttg aatataataa cctagtacaa
     6481 gatgttagaa gaagattagt atctctagca acccaaaata cagataaata cacaagtgta
     6541 ttaatgcaag gaagtgggac tttttcagta gaagctataa taggaagtac tatttcaaaa
     6601 gatggtaaac ttcttgtaat tgcaaatgga gcatatggaa agagaatgaa agatatatgt
     6661 aattatctta acatacaatt tgttgactgc acatttaaag atatagaagc agtggattta
     6721 aatgtagtag aaaatttatt aaaagaaaac aaggatataa cacatatatc aatggttcac
     6781 tgtgaaacta ctacaggtag attaaatcct atacaagagg tagggaaact tgcaaaagaa
     6841 tataacaaaa tttatatagt tgatgctatg agtagttttg ggggaattga gattgatgtt
     6901 gaagatttta atatagattt tttagttagt agttctaaca aatgtataca aggagtacct
     6961 ggatttggtt ttataatagc taataaagag aaattatcta aatgtaaagg tatagctaaa
     7021 tcattatctc ttgatgtgta tgcgcaatgg gagactatgg agaaaaataa tggtaaatgg
     7081 agatttactt cacctacaca tgttgtaaga gctttttatc aagctttatt agaattggaa
     7141 gaagaaggtt ctgttgaaaa aagatatgct agatataaag aaaatcagtt tacaatagct
     7201 tcaagattaa aatctttagg ctttgatact ttggtgaatg ataatgctca atcacctgta
     7261 ataacaactt tcttatatcc taaaaatgca aagtttgaat ttatggaatt ttatacttat
     7321 ttaaaagata atggatttgt tatctatcca ggtaaattga ctgatataga tacatttaga
     7381 ataggtagca taggtgaagt ctatccaact gatatggaga gactagctga tgtaatagaa
     7441 aaatttatca atagatagaa gaagatagtg tcttgtaggt tacagaatag tgcgcaaagc
     7501 ctactccttt aggtgtgtga gatgatagca caaacagtgt ataaaaagta ttgacagtag
     7561 aatttaaaga cttatatttt agaagtttat acaatgaata tataaacatt gagtaatagg
     7621 gatatatttt atttaaacca caatctaaga aattagattt atagtttaaa taaagcattt
     7681 ccctattatt tttatgccta tttatagaaa ataaatgata gttgctttat taagtattat
     7741 tatcatactt gacaacgtaa caatgttttg ttatattagg tttaaagata aaatacggta
     7801 aagaaaggat atcattatga atgaagaatt aagttcacta agatttgatg gtgttggaaa
     7861 atgtaaaggt ggaatttttg ataatgttaa tatatcagga acaggcaaaa tagaaggaag
     7921 tgtaaaatgt agtaaatttg attcttctgg ttcagcaaaa gtttttggga caacagaatg
     7981 taatgaattt tttacatctg gtttaagtaa agtagaagga aacatactgg catcaaaagt
     8041 tgagatatcg ggacttctta gatgtacagg aaatattaat tctgttgaaa ttgatactag
     8101 tggaattatt aatgtagaag gaagtataaa atcggatatt attcatggag aaggatattt
     8161 aaaagcaaat gagaatatag attgtgaaaa tatcaattta agtggaatct tggagtgtaa
     8221 tggatttttg aattgtgaag aagttaatat tagtttaaat ggaacttcta attttaatga
     8281 agttggagca agtagtataa atataaaaaa ggggcatgga gattattgca aaaaatttcg
     8341 tatgctagaa aaaaagcata tctctagtag ataattatga tgttggaaat attgaataca
     8401 gtgataattt atcagtttca gataattcta ctgtaaaaaa cagtataaag gtgggctaga
     8461 agagctatgg aagaattaat atctaagaaa gatttattga gcaaaactaa tatatcttat
     8521 ggacaattat atagatggaa aagaaaaaac ataataccag aggaatggtt tataaaaaaa
     8581 tcagctttta caggtcaaga gactttcttt ccaagagata aaatactaga aagaatagag
     8641 ttaatattgt ctatgaaaga agagacttct cttgattaaa aaatagctat gcacacttgt
     8701 gactttagtc atgagttagt agctaaaata gtcagcatat agggaaactt atatgtagag
     8761 ataggataga acctatccaa tactacttga attgctggaa acccctaaag ctaaccaaac
     8821 taaaacataa ggatgaaata aacctaagtg tgaaagttac gaaagtagaa aaaattggtt
     8881 agatggtata aggttaaatc ctaagtactt taaaatgggc aatcagcagg taagctccga
     8941 ataggaaaaa cttcaacgac tattcctctt gagggaagta cactacaagc tatcggtagt
     9001 ggaagtgggt agaccttaac ggataatgcc gaaggataag atatagtctg tgcttgcatg
     9061 aaagtgtaag aagttcataa gagaactgca taggtagtag cgaacttatg tgaacgacaa
     9121 cctcaaaaat gataaaagtt aagatttgcg tttcttacgt atgttattta aaaataaata
     9181 taaaaacctt aagaatactt gttttaagta attactatgt taatattatg ttgggtgatg
     9241 aaaaatggaa gtgactcatg gtagagggta tgtgtattta gtacaatacc atatagtatg
     9301 gtgtgtaaaa tatagacatc cagtattaac aaatgaaatt gaagaagatt taattaatat
     9361 attaaacaaa atagctgaag ataataaatt tcaaatatta gaatgtaata gtgataaaga
     9421 tcacatacat ttactaataa attgttcacc acaacactat ataccagata taataaaagc
     9481 attaaaaggt gtatcagcaa ggctgttaat gaaaaaacat ggagaacagt tgaaaaagaa
     9541 attatgggga ggacatcttt ggaatcctag ttatttcgtt gctactgtat cagaaaatac
     9601 agaagaacag ataagaaaat atattaataa tcagaaaaaa caagtaaagt gaggtggcag
     9661 tagtg
//
LOCUS       DAYAOO010000123         9496 bp    DNA     linear   BCT 12-OCT-2024
DEFINITION  TPA_asm: Clostridioides difficile isolate ST8-SSI-h139-18
            SAMN40601845-rid21577343.denovo.127, whole genome shotgun sequence.
ACCESSION   DAYAOO010000123 DAYAOO010000000
VERSION     DAYAOO010000123.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN40601845
            Sequence Read Archive: SRR28438827
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 9496)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9496)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-MAY-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-MAY-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002157583.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002157583.1
            Genome Coverage       :: 163x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/11/2024 16:19:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 4,038
            CDSs (total)                      :: 3,963
            Genes (coding)                    :: 3,930
            CDSs (with protein)               :: 3,930
            Genes (RNA)                       :: 75
            rRNAs                             :: 6, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 60
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 33
            CDSs (without protein)            :: 33
            Pseudo Genes (ambiguous residues) :: 0 of 33
            Pseudo Genes (frameshifted)       :: 7 of 33
            Pseudo Genes (incomplete)         :: 25 of 33
            Pseudo Genes (internal stop)      :: 11 of 33
            Pseudo Genes (multiple problems)  :: 8 of 33
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9496
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN40601845-rid21577343.denovo.127"
                     /isolate="ST8-SSI-h139-18"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Denmark"
                     /collection_date="2018"
                     /collected_by="Statens Serum Institute"
     gene            129..1328
                     /locus_tag="ACGI5H_003542"
     CDS             129..1328
                     /locus_tag="ACGI5H_003542"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436472.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9699229.1"
                     /translation="MKLKSKISIFIIFLTLAIYFSIGLLNNEDNLKIKTIKGDSNELD
                     HININFGYALNGYINSYYTINGSNKTKKTELIKLQKDSKNTNNLIDVSSGSDLIAHVG
                     FEMNEESKDINFVIDEKKEDLEKGVFPSEGSDKEIEYEKLDMNNFTRTRYKVDKSTDD
                     YYAKILASKRYKKYLYVSVLYATSDSSENNKEYSSTIDIIKINPENKKIKTIKSINLS
                     NYFSEKYQNIENIGVSYASKYEDKMYILVNVLNTNIGDNSNSKFHLLEYNLEENKESI
                     MELKTDSKMALAKAKLEANKLYMVMSNDYDNSSITELNLLTYNILDKSLDEDKYVLDN
                     REKRGIRSIEIDSNKIVAYTSRLNSILSWDDKFMLYIINKNSKEIVYEGELQFNSSNS
                     MLEFEIK"
     gene            1337..2149
                     /locus_tag="ACGI5H_003543"
     CDS             1337..2149
                     /locus_tag="ACGI5H_003543"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430030.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9699230.1"
                     /translation="MKDLIRLFEFELKRNIKNYIFIIICCCSFVILNIVKNLNDYNYI
                     IENAVKSEQLTKIGNTIETVNVTGFSSFRNIMGSTESWFMFGIIACICYAFFIWYRDF
                     NGRSKSIYTLIMLPKNRINIYISKLLNILFLVYSYTVVLTISLFIASKLLPRHMLGNV
                     TNYGFVQETIYELKMLLPYSFEILFVEYIFLLIGFVSVVFTSILINKSIYKVSTLISF
                     LFLVIEILVFIISIEFIIPYEYSDVFTVLYSSINIFVCSLISNKLLKQKIDF"
     gene            2160..3428
                     /locus_tag="ACGI5H_003544"
     CDS             2160..3428
                     /locus_tag="ACGI5H_003544"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861271.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9699231.1"
                     /translation="MKAKNIGKYTICFIIVCFLMITMTLILSYFNKDKLSVKTLKGNV
                     KDIGRVSVVYTPNISKFSYEEVIISKNGVRNNTNPKSRIRNDYLNIDKKYSDFVNDKG
                     KEFIYKDDLNIGEAYTSVKSDLVQGMNALNDCIKVSNKNLKSGVEENFDINLNKSDFK
                     ENSWKTLFNKIYKGNLYMVISETNISGSKVNNICILKIDIKNKSYKLLNRFNLGLQNG
                     EQQNINEIKFSIGSKLYLEIVNNKSKNGYIEGHDSYSNFIIYDIEDNTFNISNKFMDN
                     LNKEKNANPKEIGLLSKTKLDYMVKNNKLNLIVTDMSNSITNLVYDINSNEIKLEDYE
                     ILDLKVDYNEASSGVRKVKLLDDKIYSISGIKNSISGELKGFKGIIDVVGTKPVKFQV
                     FDMKLKKNIYEAELINGDISLQEKLFFVAN"
     gene            3794..4975
                     /locus_tag="ACGI5H_003545"
     CDS             3794..4975
                     /locus_tag="ACGI5H_003545"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430033.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidohydrolase family protein"
                     /protein_id="HFG9699232.1"
                     /translation="MNKKYIKAGNLIDGTGNSIMQNKGIIIDGDTIVEIEDIRDDLNG
                     YDVYDYLDKTVMPGIMNCHVHLTMEPVGNPKIYYDNVSDVELVVNTIKQLDAYLDSGV
                     TYIRSLGCPKYVDVQLKNLIDKGSIDGPGIVTSGPVICMTGGHGYYFGIESDGVDECR
                     KSARTVLKNGVDCVKIMATGGVTTDGVEPGSPQLTLEEMKAAVDEAIKAGKITATHAQ
                     GRTGIKNAVLAGITSIEHGVYLDDEIIDLMLERGTYLVPTVAAPYFILNAGKESGITE
                     ATLRKCEIVAIPHKESFLKAYKKGIKIAVGSDAGTSYNEHGKTYYEMKLMSDYGMDNM
                     DIIVAATKTASELLRIDKNYGTLEKGKKADVIVVNGNPVENIDVLADVLAVFKLGKKV
                     R"
     gene            complement(5117..6034)
                     /locus_tag="ACGI5H_003546"
     CDS             complement(5117..6034)
                     /locus_tag="ACGI5H_003546"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436448.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CotA family spore coat protein"
                     /protein_id="HFG9699233.1"
                     /translation="MENNKCREDFRFTQEYEEDYPNTNERYYENYQVADRYYNYPNKY
                     KEPKIKQCCCKKSMREALELLRYDALRPFVNFNQFAFISDFFIVGANLVGIDLSAPPK
                     DNLSGLDGTFERFSACNCDLIDIAGRVSYPIPVPLTLEGLINTIGTIPGVAELIALID
                     AVIPPTIDLGAILDAILAAIIDFILAASTPLANVDLASLCNLKAVAFDITPADYEDFI
                     ASLGYYLDKKHYKECNCNCDCDDCCCNKGILDNLYMSNINNQVTVVAGSLVLTGVEVL
                     GKKNDVIVLGNSNDSRIYFVCVDSIDYIA"
     gene            6287..7081
                     /locus_tag="ACGI5H_003547"
     CDS             6287..7081
                     /locus_tag="ACGI5H_003547"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436445.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HFG9699234.1"
                     /translation="MIEVDKLCKSFTRVVKDDKNKSSIRKLKKVKTKKEEFFAVNNVS
                     FKVMEGEIVGILGPNGAGKTTLLRMLGGILTPTSGSINISGYDYSIDRNSAKKEIGYL
                     SGNTKLYGRLSPRELLTTFASLYEMSKEDIEESIENIVKIMDMSEFIDNRIENLSTGQ
                     TQRTSIARCLIHSPKVYIFDEPTLGLDVLSSASIIDFMKNEKLRGKTVLYSTHYMEEA
                     ETLCDKIFMIHNGKIIASGTPQSLKEESGVNNLRDVFIKLARKEDI"
     gene            7082..9142
                     /locus_tag="ACGI5H_003548"
     CDS             7082..9142
                     /locus_tag="ACGI5H_003548"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905519.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease subunit/CPBP
                     intramembrane protease"
                     /protein_id="HFG9699235.1"
                     /translation="MRSKIVKYIFKKEMLDILRDKKTLFMMIVVPLLLYPLLMLLMIQ
                     VMNMSASSMNSKDINIAFNNKPNKVLVSMIEDDNLEKDTKNTSNDKGKIRVLDVDNYK
                     KSLEENKIDAYIKMEEKKSSINYQIYINSSQENSSNALKRIETVLDKYKRFTIEKTLS
                     EKGLDVQATLEPITYSTVDVAKTEEVAGYFLGQILPFILIIGVLLGSIYPAIDVMAGE
                     KERGTLETLFTLPISNLELVMGKYMAVSLSAIVTAILNILSMGLTMAFILVSGGISSQ
                     FGFGNFNYGDLVLPIITTLICICLFSMVVSAISMCVCSLAKSFKDAQNYITPLMLIIM
                     IPSYVSMIPNIVLDRVTAVIPVVNISLLIKSVLSFKSDLNLIALVLASNVAFVILAII
                     LLSKMFNSEEILFGNSKSFSFLEKRSNIKKGSIPTVSDGVILYAVGLVLLIYVGSLVQ
                     IKFGMAGIIMTQFMIISLPLLFAYYIKADFKEVFSLTVPKLKHVFGSIVLWIGGYILI
                     MIITQLILFLFPQNMEVAESLNKALFIKDSVLLNLLAIALLPAICEEMFFRGFIFSSF
                     SKSKDKNKSIKLAIICSGVLFGIMHMDFIRIIPTSILGIIFAYSVYKSGSIFVSMLLH
                     FLNNSVAVVLNHYTTGNITNLYKFVEVDFSNLNVLKFALILLISLILIMLGLRVLDRK
                     SLRN"
BASE COUNT         3808 a          923 c         1490 g         3275 t
ORIGIN      
        1 aatcttatag gatttcaatt taacaattta gtagcagggt tattaagttt tttaattata
       61 atgtttattc taaatggaat atcttatttg ctaattaaaa agaaagtatc tctttaagga
      121 ggggtggtat gaaattaaaa tctaaaatat ctatatttat tatatttttg actttagcaa
      181 tatattttag tataggttta ttaaataatg aagataattt aaagataaaa actataaaag
      241 gtgactctaa tgaattagac catataaaca taaattttgg atatgctttg aatggatata
      301 taaattcata ttatacaata aatggaagca acaaaaccaa aaagactgaa ttaataaaac
      361 tacaaaagga tagtaagaac acaaataatt taattgatgt atctagtggt tcagatttaa
      421 ttgctcatgt tggatttgaa atgaatgagg agtcaaaaga tataaacttt gtgatagatg
      481 agaaaaaaga agatttagaa aaaggtgtat ttccatcaga aggtagtgat aaagaaattg
      541 aatatgaaaa attagatatg aataatttta caaggacaag atataaagta gataaaagta
      601 cagatgatta ttatgcaaag atactagcat caaaaagata taaaaaatac ttatatgtat
      661 ctgtacttta tgctacaagt gattcatcag aaaataacaa agaatattca agtactatag
      721 atataataaa aattaatcca gaaaataaaa aaatcaagac tataaaaagt ataaatttaa
      781 gtaattattt ttccgaaaaa taccaaaaca tagagaacat aggtgtaagt tatgctagca
      841 aatatgagga taagatgtat attttagtaa atgtactaaa tacaaacata ggtgataata
      901 gtaattctaa atttcattta cttgagtata atcttgaaga aaataaggaa agcataatgg
      961 aattaaaaac tgatagcaaa atggctttag caaaagcaaa gttagaagct aataaattat
     1021 atatggtaat gtcgaatgat tatgataata gttcaattac agagttaaat ttacttacct
     1081 ataatatatt agataaaagc ttagatgaag ataaatatgt tttagataat agagaaaaaa
     1141 gaggaattag aagtattgaa attgattcaa ataaaatcgt tgcatataca tcaaggctaa
     1201 actctatatt atcttgggat gataaattta tgctatatat aataaataaa aattctaagg
     1261 aaattgtata tgaaggagaa ttacaattta acagttcaaa tagtatgtta gaatttgaaa
     1321 taaagtaggt gagttgatga aagatttaat aagattattc gaatttgaat taaaaagaaa
     1381 tataaagaat tatatattta taataatttg ttgttgttct tttgtaattt taaacatagt
     1441 aaaaaattta aatgactata attacataat agaaaatgca gttaaaagtg aacagttaac
     1501 aaaaatcgga aatacgatag aaacggtaaa tgttacaggt ttctcaagct ttagaaatat
     1561 aatgggttct acagaatcgt ggtttatgtt tggtataatt gcatgtattt gctatgcttt
     1621 ttttatttgg tatagagact ttaatggtag aagtaaatct atatatacac ttataatgct
     1681 acctaaaaat agaatcaata tttatatatc taaattatta aatatattat ttctagtgta
     1741 tagctataca gtagtactta caatatcttt gtttattgca agtaagttgt tgcctagaca
     1801 tatgcttggt aatgtcacaa actatggttt tgtacaagaa acaatatatg agttaaaaat
     1861 gttacttcca tatagctttg aaatactatt tgtagagtat atatttttat tgataggatt
     1921 tgtatctgta gtatttacat caattcttat aaataaatct atttataaag taagcacttt
     1981 aataagtttt ctatttttag ttatagaaat tttagtgttt ataatttcta tagaatttat
     2041 tataccttac gaatacagtg atgtatttac tgttctatat tcaagtataa acatatttgt
     2101 atgtagtctt atatctaata aacttttgaa gcaaaagatt gacttttagg agggatatta
     2161 tgaaagcaaa aaatatagga aaatatacaa tatgttttat aatagtatgt tttttaatga
     2221 ttactatgac cttaatattg agttatttta ataaggataa actatctgta aaaactttaa
     2281 aaggcaatgt aaaagatata gggagagtaa gtgtagtata tacacctaat ataagcaaat
     2341 tttcttatga ggaggtaatt ataagtaaaa atggagtaag aaataataca aacccaaaat
     2401 caagaattag aaatgattat ttaaatattg acaaaaaata cagtgacttt gttaatgata
     2461 aaggaaaaga atttatatat aaagatgatt tgaatatagg agaagcgtat acctctgtta
     2521 agtctgattt agtacaagga atgaatgctt taaatgattg tataaaggtt tcaaataaaa
     2581 atttaaaaag tggggtagaa gaaaattttg atattaattt aaataagtct gattttaaag
     2641 aaaatagttg gaaaacctta tttaacaaaa tatataaagg taatttatat atggtaatta
     2701 gtgaaactaa tatttcaggt tctaaagtca ataatatttg tatattaaag atagatataa
     2761 aaaataagtc ttataaatta ttaaatagat ttaatttagg attacagaat ggagaacaac
     2821 aaaatatcaa tgaaattaaa ttttctattg gaagtaaatt atacttagaa atagtaaata
     2881 ataaaagtaa aaatggatat attgaaggac atgatagtta ctctaacttt attatatatg
     2941 atatagaaga taacactttt aatataagta ataaatttat ggataatcta aacaaagaaa
     3001 agaatgcaaa tccaaaggag attggcttat taagtaaaac taagctagat tatatggtaa
     3061 aaaacaataa attgaatctt atagttacgg atatgagtaa ttccataact aatcttgttt
     3121 atgatattaa ttctaatgag attaaattag aagattatga gatacttgat ttaaaagtag
     3181 attataatga agcatcatct ggagttagga aagttaagct actggatgat aagatatatt
     3241 ctatttcagg tattaagaac agtatatcag gagaattaaa aggatttaaa gggattattg
     3301 atgtagtcgg aactaagcca gtaaaatttc aagtatttga tatgaaactt aaaaagaata
     3361 tttatgaagc tgagctaata aatggagata taagtttaca agaaaagtta ttttttgttg
     3421 caaattaagt gttagaatta attttagaac tttaaacttt tatatgtatc acagataagt
     3481 ataagtaagg gagtgtctca aaataaactt tttagctcat gagacacttt ttttatatga
     3541 aatcaaatat attttcattg tttagattta ttttgataat gaaaaaaaga ttatctttat
     3601 tttaagaaag acatttattt ataattatat acaaaaatat tttttaatgt ttttgtgtat
     3661 aattataaca atttaattta tattaatgca cttaaatttg aaatagaatg cttatagtgg
     3721 taaaattaat tattagaata ttagaaataa taaataaata atacattgta cttaaaaggg
     3781 ggagaaattt aagatgaaca aaaaatatat taaagcaggg aatttaattg atggaaccgg
     3841 aaatagtatt atgcaaaata agggtataat tattgatgga gatactatag ttgaaattga
     3901 agatataaga gatgatttaa atggatatga tgtgtacgat tacttagata aaactgttat
     3961 gccaggcatt atgaattgtc atgttcactt gacaatggag ccagttggaa atccaaagat
     4021 atattatgat aatgtatcag atgtagagct tgtagtaaat acgataaaac aacttgatgc
     4081 ttatttggat tcaggagtaa catatattag aagcttaggt tgtcccaaat atgtggatgt
     4141 acaacttaaa aatcttatag acaaagggtc tatagatggt cctggtatag ttacttcagg
     4201 tccagttata tgtatgacag gagggcatgg atattatttt ggtattgaaa gtgatggagt
     4261 agatgaatgt agaaaatcag ccagaacagt tttaaaaaat ggagtagatt gtgtaaagat
     4321 aatggcaact ggaggtgtaa caactgatgg agttgagcca gggtcaccac aattaacttt
     4381 ggaggaaatg aaggctgctg tagatgaagc tataaaagca ggtaaaataa ctgccacaca
     4441 tgcacaagga agaactggta taaaaaatgc agtgcttgca ggaattactt ctatagaaca
     4501 tggtgtttat ttagatgatg aaataattga tttgatgctt gaaagaggaa cttacttagt
     4561 tccaactgtg gctgcaccat attttattct aaatgcagga aaagaaagtg gaataactga
     4621 agctactctt agaaagtgtg agattgttgc cattccacac aaagagtcat tcctaaaagc
     4681 atataaaaaa ggaattaaaa ttgcagttgg ttctgatgca ggaacttctt ataatgaaca
     4741 tggaaaaaca tattatgaaa tgaaactaat gtcagattat ggtatggata atatggatat
     4801 aatagttgct gctacaaaaa cagcatctga acttttaaga attgataaaa attatggaac
     4861 tctagaaaaa ggaaagaaag cagatgttat agttgtaaat ggaaatccag tagagaatat
     4921 agacgtactt gcagatgtgt tagcagtatt taaacttggt aaaaaagtta gataaatagt
     4981 ataaaaataa aaaagagtgt ctaaagaaat ttttaaataa ttatagacac tcttttttat
     5041 tagtaataat taaatctttt atactttaga aaatagattc tattttatat ttagatataa
     5101 ctctttaaaa tcattcttat gcaatataat ctatagaatc tacacataca aagtatattc
     5161 ttgaatcatt agaatttcca agtactataa catcattttt cttacctaga acttcaacac
     5221 cagttagaac caaactacca gctactacag taacttgatt atttatattt gacatataaa
     5281 gattatctag gataccttta ttacaacagc aatcatcaca atcgcagttg caattacatt
     5341 ctttgtaatg ttttttatca agatagtaac ctaaagatgc tatgaaatct tcataatctg
     5401 caggtgtaat atcaaatgca acagctttaa gattacacaa tgatgctaaa tctacgtttg
     5461 ctaatggagt agatgcagca agtataaaat caattatagc agcaagtatt gcatctaata
     5521 tagccccaag gtctatcgta ggaggaataa ctgcatcaat aagtgcaatt aattcagcta
     5581 ctcctggtat agttcctata gtattaatta atccctcaag agttaaaggg actggaatag
     5641 gataagatac tctaccagct atatctatta aatcacagtt acaagcagaa aatctttcaa
     5701 aagtaccatc aagtccagat aaattatctt ttggaggagc tgaaagatct atacctacca
     5761 aattagcacc tactataaag aaatctgaga taaaagcaaa ttgattaaag tttacaaaag
     5821 gtcttagagc atcatatctt agaagttcta atgcttctct catacttttt ttacaacaac
     5881 attgttttat tttaggttct ttatatttat ttggataatt atagtatcta tcagctactt
     5941 gataattttc atagtatctt tcatttgtat ttggataatc ttcctcatat tcttgtgtaa
     6001 atctaaagtc ctctctacat ttattatttt ccactaaata cactcctttt atattttaat
     6061 ttaaatgtat agataattaa gcttatctat atagtaatat tatatttata atgtaaaaaa
     6121 atgttacaaa agatattata aacgaataaa aaataataat ttgtcagata aacttgtaaa
     6181 tttttatgaa taatccattc taaaacaaaa aactgtgtat aaaaaaggtt tatatgttat
     6241 atttatataa atataacata tgaacgagaa aggagtggtt tgataaatga ttgaggtaga
     6301 taaattgtgt aagtctttta caagggttgt aaaagatgat aagaataaaa gttcaataag
     6361 aaagctaaag aaagtaaaaa ctaaaaaaga agaatttttt gctgtaaata atgtttcatt
     6421 taaagttatg gaaggtgaaa ttgttggaat attaggtcca aatggtgcag gaaagactac
     6481 attacttaga atgttaggtg gcatattaac accaacatca ggaagtataa atatttctgg
     6541 atatgattat tcaatagata gaaattcagc aaaaaaagaa ataggttatc tctctggaaa
     6601 tacaaaacta tatggaaggc tttctccgag agaacttcta acaacttttg caagtctata
     6661 tgagatgtca aaagaagata tagaagaatc aattgaaaat attgtaaaaa taatggatat
     6721 gagtgaattt atagataata gaattgaaaa tctatcaact ggtcagactc aaagaacatc
     6781 tatagctcgt tgtttaatac attctccaaa agtatatatt tttgatgagc caacactagg
     6841 tctggatgtt ttaagtagtg catctattat agattttatg aagaatgaaa aactaagggg
     6901 aaaaactgtt ctttactcaa ctcattatat ggaagaagca gaaactttat gtgacaagat
     6961 ttttatgatt cacaatggga aaataattgc atcaggaaca ccacagagtt taaaagagga
     7021 atctggagta aataatttga gagatgtatt cataaaactt gccagaaagg aggacattta
     7081 aatgagaagt aagattgtaa aatacatatt taaaaaagaa atgttagaca tattgagaga
     7141 taaaaagact ttatttatga tgattgttgt gccacttctt ttatatcctt tacttatgtt
     7201 attaatgatt caagtaatga atatgtctgc aagtagtatg aatagtaagg acattaatat
     7261 agcttttaat aataaaccta ataaggtgtt agtatccatg attgaagatg ataatttaga
     7321 aaaagatact aaaaatactt caaatgataa aggcaaaata agagtgttag atgtagataa
     7381 ctataaaaag tcattagaag aaaataaaat tgatgcttat ataaagatgg aagaaaaaaa
     7441 atcatctata aattatcaaa tatatataaa ttcttctcaa gaaaattctt ctaatgcact
     7501 aaaaagaatt gaaactgttt tggataaata taaaagattt accatagaaa aaactttatc
     7561 tgaaaaagga ttagatgtac aagctacttt agaaccaata acatatagca ctgtagatgt
     7621 tgcaaagacg gaagaagtgg caggatactt tttaggtcag atacttccat ttatattaat
     7681 aataggagtt ttactaggtt caatatatcc agcaatagat gttatggctg gagaaaagga
     7741 aagaggtaca ttagaaacat tatttacact gccaatatca aacttagaac tggttatggg
     7801 aaaatatatg gcagtttctc ttagtgcaat agtaacagca attttaaaca ttttatctat
     7861 gggactgact atggcattta ttttagttag tggaggtatt agtagccaat ttggctttgg
     7921 aaactttaat tatggagact tagtcttacc aattataact actttaattt gcatatgtct
     7981 tttttcaatg gtagtttcag caataagtat gtgtgtatgt tcattagcaa aaagttttaa
     8041 agatgctcaa aactacataa cacctcttat gttaattatt atgataccat catatgtttc
     8101 tatgatacca aatatagtat tagatagagt gacagctgta atacctgtag taaatatatc
     8161 tttacttata aaaagtgtat tatcttttaa aagcgattta aatttaatag ccttagtttt
     8221 agcatcaaat gtagcctttg ttatattggc aatcatacta ctgtctaaga tgttcaattc
     8281 tgaggaaata ctttttggta atagtaagag tttttctttc ttagagaaaa gaagtaatat
     8341 aaaaaaaggg tctataccaa ctgtaagtga tggtgttatt ttatatgcag taggattagt
     8401 tctattgatt tatgttggtt ctttagttca aattaaattt ggtatggcag gtattataat
     8461 gacacaattc atgataattt ctttaccatt attatttgca tactatatta aagctgattt
     8521 taaagaggta tttagcttga cagttcctaa attaaagcat gtgtttggga gcattgttct
     8581 ttggattggt ggatacatac ttattatgat tataacacag ctaattttat tcttatttcc
     8641 tcaaaatatg gaagttgctg aaagtttaaa taaggctctt tttatcaaag atagtgtttt
     8701 actgaattta ctagcaatag ctttattacc agctatatgt gaagaaatgt tttttagggg
     8761 atttatattt tcttcattta gtaaatcaaa agataaaaat aagtctatca aactcgctat
     8821 aatatgtagt ggggtactat ttggtattat gcatatggat tttattagaa taattccaac
     8881 atcaatatta ggtattatat ttgcatacag tgtgtataaa tctggttcaa tatttgtatc
     8941 aatgttattg cattttttaa ataatagtgt agcagttgtg ttaaatcatt atacaactgg
     9001 aaatataacc aacttatata aatttgttga agttgatttt tcgaacttaa atgtgcttaa
     9061 atttgcctta attcttctaa taagtcttat attaattatg ttaggattaa gagttttaga
     9121 tagaaagtct ttaagaaatt aagtataaag ttattatata gattaaaata ttaataagca
     9181 ctaaagtata tggatatatc ttgtatataa aaatacttta gtgctatttt atatatttta
     9241 attatatgaa ttatttatcg tttcatttat gtaatgaaaa tgttatataa atgaaacaat
     9301 aaataatttt tattttagaa atttatattt aaataatcaa gttgaaagtg agatactaaa
     9361 aaaattaatt taggaattat ttgatttatt catttataaa aattaattac tgatttgtcg
     9421 aaaccattgt aataagaaaa aaatgaaaaa ataaagtgtg aatatgttgc aaatactgta
     9481 ttttaataaa aagtag
//
LOCUS       DAYAOO010000124         9191 bp    DNA     linear   BCT 12-OCT-2024
DEFINITION  TPA_asm: Clostridioides difficile isolate ST8-SSI-h139-18
            SAMN40601845-rid21577343.denovo.128, whole genome shotgun sequence.
ACCESSION   DAYAOO010000124 DAYAOO010000000
VERSION     DAYAOO010000124.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN40601845
            Sequence Read Archive: SRR28438827
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 9191)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9191)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-MAY-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-MAY-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002157583.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002157583.1
            Genome Coverage       :: 163x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/11/2024 16:19:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 4,038
            CDSs (total)                      :: 3,963
            Genes (coding)                    :: 3,930
            CDSs (with protein)               :: 3,930
            Genes (RNA)                       :: 75
            rRNAs                             :: 6, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 60
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 33
            CDSs (without protein)            :: 33
            Pseudo Genes (ambiguous residues) :: 0 of 33
            Pseudo Genes (frameshifted)       :: 7 of 33
            Pseudo Genes (incomplete)         :: 25 of 33
            Pseudo Genes (internal stop)      :: 11 of 33
            Pseudo Genes (multiple problems)  :: 8 of 33
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9191
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN40601845-rid21577343.denovo.128"
                     /isolate="ST8-SSI-h139-18"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Denmark"
                     /collection_date="2018"
                     /collected_by="Statens Serum Institute"
     gene            393..1598
                     /locus_tag="ACGI5H_003549"
     CDS             393..1598
                     /locus_tag="ACGI5H_003549"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426064.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016758 - hexosyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HFG9699236.1"
                     /translation="MSKKVLIMSASTGGGHNRAALAIKEELTSKTLDGEPIECEIIDS
                     LKLVNNTMDKIISRGYEKSAIYTPKAYGSVYRLSETNLLSKNEFKDNLLITFMAKKFK
                     KLIRSEKPDLIIGTHPFPMIALSTLKKNFNLHNNESNAYTEHFYKHYTNTINVPPLIS
                     VLTDYTTHSTWIQNEIDYYIVGHEYVKELLVFDGVEPSKIRTFGIPVEKSFLSHRDKG
                     IVLSELNLSPDKLTVLLMGGSFGAGNIKETLDELLDTDRDFQILVITGKNESLKEKIE
                     KKLMSRYHDKNVCVLGYTDKMNDILASIDVLVSKPGGLTTTEALLKDVPMIVPYYIPG
                     QEEENLDFLSNCGAALRTTKKYNLSILLKVLIDDPSRLEMLKRNIKSIRKSNSAQNIA
                     NLILNIISG"
     gene            complement(1669..1890)
                     /locus_tag="ACGI5H_003550"
     CDS             complement(1669..1890)
                     /locus_tag="ACGI5H_003550"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421616.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9699237.1"
                     /translation="MKPIMNLEEHNAMKEKRVKKMKSKDKPKYDDFEDISFSNKKKTK
                     KNVRNKNAEFRNNYKNYQYDYEEDFYEPI"
     gene            complement(2031..2630)
                     /gene="recR"
                     /locus_tag="ACGI5H_003551"
     CDS             complement(2031..2630)
                     /gene="recR"
                     /locus_tag="ACGI5H_003551"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421618.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="recombination mediator RecR"
                     /protein_id="HFG9699238.1"
                     /translation="MQVYTGPITRLIEEFSKLPGVGRKTAQRLAFHIINMNTNDVEAL
                     SKAIIDAKREIRYCSICCNITDTDPCSMCSNKSRDSSVICVVEDPRDVAAMERTREFK
                     GQYHVLNGVISPMDGIGPDMLKIKELIQRLGNQEVKEIIMATNPTIEGEATAMYIARL
                     VKPMGIKVTRIAHGLPVGGDLEYADEVTISKALEGRREI"
     gene            complement(2643..2993)
                     /locus_tag="ACGI5H_003552"
     CDS             complement(2643..2993)
                     /locus_tag="ACGI5H_003552"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009887752.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0008150 - biological_process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="YbaB/EbfC family nucleoid-associated protein"
                     /protein_id="HFG9699239.1"
                     /translation="MAKKGFGGGMMPGGGNMNNLLKQAQKMQENMQKAQQELESKEVE
                     ASVGGGAVTVKVNGKKEVIDITIKPEVVDPDDIEMLQDLVLSAVNQALRNIDDIQASQ
                     MSKVTGGMNIPGLF"
     gene            complement(3052..4689)
                     /gene="dnaX"
                     /locus_tag="ACGI5H_003553"
     CDS             complement(3052..4689)
                     /gene="dnaX"
                     /locus_tag="ACGI5H_003553"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421622.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009360 - DNA polymerase III complex
                     [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003887 - DNA-directed DNA polymerase
                     activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006260 - DNA replication [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit gamma/tau"
                     /protein_id="HFG9699240.1"
                     /translation="MHKALYRAYRPQKFEDVIGQDHIIKTLKNQIYSDNIGHAYLFCG
                     TRGTGKTSTAKIFSRAVNCLNKINEEPCNECEICESVLKDNTMDVVEIDAASNNSVDD
                     IRELRESVKYSPANAKYKVYIIDEVHMLSQGAFNALLKTLEEPPSYVIFILATTEPHK
                     IPATILSRCQRYDFKRVTVKDMTLRMKKICEDEGIDIDDKALNLIARNSQGALRDALS
                     ILDQCMSFGESKIDYKDVVELMGSVNIEQLFELSQCIVEQDTKKSLEILNEFVLWGKD
                     IRNLINDLIDHFRNLMVCKVSSELDEIISLPEETIEQLKIQSKNIDINDLIRILNILS
                     ITQDDIKSSSNPRVLVEITIMKIAQPMFDESKEALIKRVENLEKMIELGNFKSEKIGN
                     NKEKEYEVDREIDVKQENVVYEDVKNEDVILIESSWKNILKQIKKDKKMPIYALLSEV
                     KSFNVYSNMLYVIFDDKFDFAKTRLSSQDTINYLEKTIRDVLNRSFNVKIVLTSEVKD
                     INLEVKEKKDIGEEILKNIVSEEILEIKDSIDENESK"
     gene            complement(4766..5030)
                     /gene="ffs"
                     /locus_tag="ACGI5H_003554"
     ncRNA           complement(4766..5030)
                     /ncRNA_class="SRP_RNA"
                     /gene="ffs"
                     /locus_tag="ACGI5H_003554"
                     /product="signal recognition particle sRNA large type"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF01854"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF01854"
     gene            complement(5068..5159)
                     /locus_tag="ACGI5H_003555"
     tRNA            complement(5068..5159)
                     /locus_tag="ACGI5H_003555"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(5123..5125),aa:Ser,seq:gga)
     gene            complement(5160..5615)
                     /locus_tag="ACGI5H_003556"
     CDS             complement(5160..5615)
                     /locus_tag="ACGI5H_003556"
                     /EC_number="3.5.4.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421624.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA];
                     GO_function: GO:0052717 - tRNA-specific adenosine-34
                     deaminase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside deaminase"
                     /protein_id="HFG9699241.1"
                     /translation="MESSFYMKEALKEAYKAYNKKETPIGAIIVKDNQIIARAHNLTE
                     TLKDSTAHAEILAIKQASEKLGGWRLTDCDLYVTMEPCIMCSGAIVNSRIKKLIIGTR
                     HVKNSYIEKQHEFKLDYFNNNNVKVAFDVLQEECSIILQEFFKALRKRD"
     gene            complement(5936..7207)
                     /gene="serS"
                     /locus_tag="ACGI5H_003557"
     CDS             complement(5936..7207)
                     /gene="serS"
                     /locus_tag="ACGI5H_003557"
                     /EC_number="6.1.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006441208.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0004828 - serine-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006434 - seryl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="serine--tRNA ligase"
                     /protein_id="HFG9699242.1"
                     /translation="MLDIKRIRENLDDIKKAMERRGEREFDLDAVVELDNKRREILQE
                     VEVMKNELNVNSKKIPQLIKEGKDVTEEKARLKELSDKIKGIDEKVKEVEAKMEYTLM
                     RIPNVPHPEVPQGETDEDNVQIRTWGEPTKFDFEHKAHWDIGTGLGILDFERAGKITG
                     SRFTLYRGLGARLERSLMNFFLNTHTAKHGYTEVLPPFMANRNSFIGTGQLPKFEEDM
                     FKIEGLEYFLIPTAEVPVTNIHANEILDVAELPIKYCAYTPCFRSEAGSAGRDTRGLV
                     RQHQFNKVELVKFVKPEDSYNELESLTHDAETMLQMLGLPYRVVKICTGDLGFTAAFK
                     YDLEVWMPSYNRYVEISSCSNFEDFQARRAGIRFKRDKKSKAEYVHTLNGSGLAIGRC
                     LAAILENYQQADGSVVVPEELRPYMGVDVIK"
     misc_binding    complement(7333..7538)
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            complement(7666..8547)
                     /locus_tag="ACGI5H_003558"
     CDS             complement(7666..8547)
                     /locus_tag="ACGI5H_003558"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421629.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="mechanosensitive ion channel domain-containing
                     protein"
                     /protein_id="HFG9699243.1"
                     /translation="MNFLSLAKTASTNSNITKRTLENMLDNFSDNIPNIIYAIIVFVI
                     GIYISKIVRRMVSKFLIKYGMSKGVNNFIVYGIYISMLSIISLISLGIIGIQTTSVVA
                     VLGAAGFSIGLAFKEILSNLGSGMIILFFKPFNIGDYIQGSGVEGTVSDIQIFSTVLK
                     TPDNKTIIIPNFQLTSNNIINYTHQNKRRIDFSYNISYDSDIDVVKSILNEIFTNEKR
                     ILNDPKPIIGLNSIGNNTMQIVARPWVKTDDYWDVYFDVMEKVKNKFDENDIKVPFVP
                     SSLLFNNTGNLNTMDKR"
     gene            complement(8559..9068)
                     /locus_tag="ACGI5H_003559"
     CDS             complement(8559..9068)
                     /locus_tag="ACGI5H_003559"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421631.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription repressor NadR"
                     /protein_id="HFG9699244.1"
                     /translation="MNSNERRSKLIDILKESKHPVKGGTLAELLNVSRQVIVQDIALI
                     RARGFEIIATPQGYIIYNQPYFTKQIKCKNHKDSKEIYDELKIIVDLGGIIKDVIVNH
                     PTYGQITAELNIYSKMDIDNFMKKVETNEFKQLSVLTECSHIHTIEAIKEETIEAIVK
                     ELKDNGILS"
BASE COUNT         2943 a         1598 c          973 g         3677 t
ORIGIN      
        1 ttcctttttt caaggacaag taatactata tcatctttat ctattctagt caatataatt
       61 ttttactttt tttatttttt ttatttatca tgtattcttt atatttaatt tttaaaactt
      121 aatgctaagt aaacctgttt atttcataaa actaatatat attctatgct ctattttcct
      181 ttttattcta tatttaaatt ttttatttac aagaatattt ttaatataac atatttgata
      241 aaattaattt acatttcttt cacttgtaat ttttgcaatc ttgtattaga ttaatattaa
      301 aaataattta tcaataacct tattcacaaa gacagttttt atatatcaaa atataatata
      361 aatactatgc tacattttag gaggatttta ttatgagcaa aaaagtatta ataatgtctg
      421 cttccactgg tggtgggcat aatagggctg ctctagctat taaagaagaa cttacttcca
      481 aaacacttga tggagagcca attgaatgtg aaataataga tagtttgaaa ttagttaata
      541 atacaatgga taaaataatt tcaagaggat acgaaaaatc tgctatatat actcccaaag
      601 cctatggaag tgtatataga ttatctgaaa caaatctttt atcaaaaaat gaatttaaag
      661 ataatctact aataacattc atggctaaaa aatttaaaaa acttattaga agcgaaaaac
      721 cagacttgat tataggaacg catccttttc caatgattgc tctaagtaca ttgaaaaaaa
      781 actttaattt acataataat gaatcaaatg cttacacaga gcatttttat aaacattata
      841 caaataccat taatgttcct ccgcttattt ctgtattaac cgattatact actcattcta
      901 catggataca aaatgaaatt gattactata ttgttggtca tgaatatgta aaagaattat
      961 tggtgtttga tggagttgaa ccgagtaaaa ttagaacatt tggaatccct gttgaaaaat
     1021 cttttctctc tcacagagat aaaggtattg ttctttctga gttgaattta tctcctgata
     1081 aattaactgt tttacttatg gggggtagct ttggggctgg aaatataaaa gagacacttg
     1141 atgaattact ggatactgat agagactttc aaatacttgt aattactggt aagaatgaaa
     1201 gcctaaaaga aaaaatcgaa aaaaaactta tgtctcgtta tcatgataaa aatgtatgtg
     1261 ttcttggata cactgataag atgaatgata ttttagcttc tatagatgta ttagtaagca
     1321 aacctggtgg acttactaca actgaggctc ttttaaaaga tgtacctatg atagttcctt
     1381 attatatacc aggtcaggaa gaagagaatc ttgatttctt atctaattgt ggtgcagcac
     1441 ttagaactac aaaaaaatat aacttgtcaa tattactaaa agttttaata gatgacccta
     1501 gcagattaga aatgctaaaa agaaatatta aatcaataag aaagtcaaat tcagcccaaa
     1561 atatagctaa tttaatttta aatataattt ctggttgata aaataaataa aatccctata
     1621 gtatatatat tatctattag ggatttttta ttttctaatt atttaatatt aaattggttc
     1681 ataaaagtct tcttcataat catactgata atttttataa ttatttctaa attcagcatt
     1741 tttatttcgt acattttttt tagttttttt cttattagaa aaacttatat cctcaaaatc
     1801 atcatattta ggtttatctt ttgatttcat ttttttaact cttttttctt tcattgcatt
     1861 atgttcttct aagttcataa ttggtttcat gttgcacccc tatcaaaatt tttaaatgat
     1921 ttatacaaca aattatacaa tacagaagaa atttattcaa taaatctaaa tcaaaattaa
     1981 tttgaattta actcaaaaaa ttacaaaaat cgaggtatta acctcgattt ttatatttct
     2041 cttctgcctt ctagtgcttt tgatattgtg acctcatctg catactctaa atcgcctcca
     2101 acaggaagac catgagctat ccgagtgact ttgattccca ttggttttac taacctagca
     2161 atatacatgg ctgtagcttc accttcaata gtaggatttg ttgccattat tatttctttg
     2221 acttcctgat tgccaagtct ttggataagt tcctttattt ttaacatatc tggtccaatt
     2281 ccatccattg gagaaattac tccatttaat acatggtact gtcctttaaa ctctctcgtt
     2341 ctctccatag ctgctacatc tcttggatct tccacaacac atataacact tgaatctcta
     2401 cttttatttg aacacatgct acatgggtct gtatctgtta tattacaaca aattgagcaa
     2461 tatcttattt ctctttttgc atctataatc gctttagata aagcttccac atcattagta
     2521 ttcatattaa taatatgaaa agccaatctt tgagcagtct ttcttcctac tccaggaagc
     2581 tttgaaaatt cctctataag tctcgttatg ggacctgtat aaacttgcat aaataccacc
     2641 tactagaata acccaggtat attcatacct ccagttacct tactcatttg acttgcttgt
     2701 atatcatcaa tatttctcaa tgcttgattt actgcactta aaactaaatc ttgtagcatt
     2761 tctatatcat ctggatcaac tacttctggc ttgatagtta tatctataac ttctttttta
     2821 ccattaactt ttacagtaac tgctcctcca ccaactgaag cttctacttc tttactttct
     2881 aactcttgtt gagctttttg catattttct tgcatttttt gagcctgctt taacaagttg
     2941 ttcatatttc caccaccagg catcattccg cctccaaaac cttttttagc cataaacact
     3001 attcctccta aacttatttt cattttatta ttatatcata atagtatttt attatttact
     3061 ctcattttca tcaatactat cttttatttc taatatctct tcactcacta tgttctttaa
     3121 tatttcctca ccaatgtcct ttttctcttt aacttcaaga tttatatctt taacttctga
     3181 tgtcagtact atttttacat taaaacttct atttaaaaca tctcttattg ttttttctaa
     3241 ataatttatt gtatcttgag agctcagtct agtttttgca aaatcaaatt tatcatcaaa
     3301 tataacatac aacatattag aatatacatt aaaacttttt acttcactta agagtgcgta
     3361 tattggcatt tttttatctt ttttaatttg tttaagtata ttcttccaag atgactctat
     3421 aagtataacg tcctcatttt ttacatcttc ataaactaca ttttcttgtt ttacatctat
     3481 ttctctatcg acctcatact ctttttcttt attattccca attttttcag acttaaagtt
     3541 ccccagttca atcatttttt ctaagttctc aactcttttt ataagagctt ctttactttc
     3601 atcaaacatt ggttgagcaa ttttcattat ggttatttcc actaaaaccc ttggatttga
     3661 agatgacttt atatcatcct gagttattga taatatattt aaaatcctta ttaaatcatt
     3721 tatatctata tttttagact gaattttaag ttgttctata gtttcttctg gtaatgaaat
     3781 tatttcatcc aattctgatg aaaccttaca taccattaaa tttctaaaat gatcaattaa
     3841 gtcatttata agatttctta tatctttgcc ccataagaca aattcattta atatctcaag
     3901 agacttttta gtgtcctgct ctactataca ttgagacaat tcaaataatt gttctatatt
     3961 tacgcttccc attaattcaa caacatcttt ataatctatc ttactttctc caaaagacat
     4021 acattggtct aatatactaa gtgcatctct aagagctcct tgagaatttc tagctattaa
     4081 attaagagct ttatcatcta tatcaattcc ttcatcttca caaatctttt tcattctaag
     4141 ggtcatatct ttaactgtaa ctcttttaaa atcgtatctt tggcatcttg ataaaatggt
     4201 tgcaggtatt ttgtgaggct ctgtagttgc taatataaaa attacatatg atggaggttc
     4261 ctctaaggtc tttaataatg cattaaaagc tccttgagac aacatatgaa cttcatctat
     4321 tatatatact ttatatttag cattggctgg agaatatttc acactttctc taagctctct
     4381 tatatcatct acactattat ttgaagctgc atctatttct acaacatcca ttgtattatc
     4441 ttttaataca gattcgcata tctcacactc attacacggt tcttcattta ttttattcaa
     4501 acagtttact gctcttgaaa aaatctttgc agtagatgtt ttaccagtac ctcttgttcc
     4561 acaaaacaaa taagcatgtc ctatattatc actatatatt tgattcttta aagtcttaat
     4621 aatatgatct tgaccaataa catcttcaaa tttttgtggt ctatatgctc tatataatgc
     4681 tttatgcatc tttttacctc tctttagcaa aattaataaa aaaatccctc attatctaag
     4741 ggattagtct tttatatatt aaatgctgta caccatctat cgacttaatt ccataggcgt
     4801 taccaaaaca gttagctcaa cttaggcacc cccacggcac acaaaagtga tcacttaccg
     4861 ctgcttcctt ccggatctga cggggttcat gagctttcat tgcgcaggac ctaagcatca
     4921 acaccactta tttagggcgg ccctacagaa aataagcctt tagatggaat tcaatcctgc
     4981 tatagcggat tgcaggttac agggcaccgc tacctcccca tctagtacag caaaattaca
     5041 accatattta attactttca ttgtttctgg cggagagagt gggatttgaa cccacgatac
     5101 agttttaccc atatactcgc tttccaggcg agcgccttcg accactcgac catctctcct
     5161 taatctcttt ttctcaatgc cttaaaaaat tcttgcaata tgatcgagca ttcttcttgc
     5221 aaaacatcaa aagctacttt tacattatta ttattaaaat aatctaattt aaactcatgc
     5281 tgtttttcta tatatgaatt ttttacatgt cttgtcccta ttataagctt ttttattcta
     5341 gaattaacta ttgcgccact acacattatg caaggttcca ttgtaacata taaatcacaa
     5401 tcagtcaacc tccaaccacc taatttttct gatgcttgtt ttatcgctaa aatttctgca
     5461 tgtgccgtag agtcttttaa cgtttctgta aggttatgag ctctagctat tatttgatta
     5521 tctttaacta taatagcacc tattggtgtt tcttttttat tatatgcttt atatgcttct
     5581 tttaatgctt ctttcatata aaatgaactt tccataattc ctcccaaaac ttataacaaa
     5641 cttatcttat cataattcat tttataattc aacttaattt tattttgttt atttaattat
     5701 tactatatat agctatattt ttttaaaatt agttctaaaa taatttttag atattcatac
     5761 aagagtgttt tataaaaata tttagtgttt tatgatgaaa attctgctgt gtaaattaac
     5821 ataaaaaaac tatgaaatta atatttataa taatttcata gtttttttat ttattgttta
     5881 ctcataatat attctcttca tcaaagcata ctctatatat acaattaata taaatttatt
     5941 ttataacatc aacacccata taaggtctta attcttctgg aactactaca gaaccatctg
     6001 cctgctgata attttctaat atagcagcca aacatcttcc tattgctaat ccagaaccat
     6061 ttaatgtatg aacatattct gcttttgatt ttttatctct tttaaatctt attcctgctc
     6121 ttcttgcttg gaaatcttca aaatttgaac aagaagatat ttctacatat ctattgtaac
     6181 ttggcatcca aacttctaaa tcatatttaa atgcagctgt aaatcccaaa tctcctgtac
     6241 atatttttac aactctatat ggaagaccta acatttgtaa catagtttca gcatcatgag
     6301 ttaatgattc taattcatta taagaatctt ctggtttaac aaatttaact aattcaactt
     6361 tattaaattg atgttgtcta actaaacctc ttgtatctct tcctgctgaa cctgcttcag
     6421 atctaaaaca aggagtatat gcacagtatt taattggaag ctctgcaaca tctaatattt
     6481 cattagcatg tatattagta acaggaactt cagctgttgg tattaagaaa tactctaatc
     6541 cttctatttt aaacatatct tcttcaaatt taggaagttg accagtccct ataaaactat
     6601 ttctattggc cataaatgga ggtaagactt ccgtatagcc atgcttagct gtatgagtat
     6661 ttaaaaagaa attcattaaa gatctttcta atctagctcc taatccccta tataaagtaa
     6721 accttgaccc agttattttc cctgctcttt caaaatctaa aatacctaga cctgtaccta
     6781 tatcccaatg cgctttatgc tcaaaatcaa atttagtagg ttctccccaa gttcttattt
     6841 gaacattgtc ttcatctgtt tcaccttgtg gtacctctgg atgaggaaca tttggtattc
     6901 tcattaatgt atattccatt tttgcttcta cttcttttac tttctcatca atacctttta
     6961 tcttatctga taactctttc aatcttgcct tttcttctgt tacatctttt ccttctttta
     7021 ttaattgagg tattttttta gaatttacat ttaactcatt tttcataact tcaacttctt
     7081 gaagtatttc tcttctttta ttatctaatt ccactacagc atcaaggtca aattctcttt
     7141 cacctcttct ttccatagct tttttgatat catctagatt ttctcttatt cttttaatat
     7201 ctaacatatt aattcctcct aataattttg ataatataag ttataattcc aacttaattt
     7261 acaaacatta tacttgtaaa ctcttagttt aaacaaattt taaaaataaa aaaagacctc
     7321 cgtttaccct ataaaaggga cgaaaatctt ttatccgcgt tgccacccta attgactata
     7381 ctaaaatgta taatcctctc agacctataa cgtaggtaaa cgtctagctt taactagaag
     7441 ctctagagta gattcaaaaa ccattgtaat gagttttcac catccactca ttctctgaat
     7501 acaatctgtt ttttactatt ttccttcaca gctttttaac taattgtttt atttgataat
     7561 cattatatta tatatattaa catctttcaa tactattatt caaatttttt tagaattttc
     7621 tttaattttt tatattaaat tcattttttc tatttaatta aaaccttatc ttttatccat
     7681 tgtatttaga ttacctgtat tattaaataa taatgaagaa ggaacaaatg gaacttttat
     7741 atcattctca tcaaatttat tttttacctt ttccattaca tcaaaatata catcccagta
     7801 atcatcagtt tttacccaag gtctagcaac tatttgcatg gtgttatttc ctatagagtt
     7861 taaacctatt ataggctttg gatcatttaa tattcttttt tcgtttgtaa aaatttcatt
     7921 taatatagac ttaactacat ctatatcact atcatatgaa atattatatg aaaaatctat
     7981 tcttcttttg ttttgatgtg tgtaattaat tatattatta cttgtcagtt gaaaattagg
     8041 tataattata gttttattat ctggcgtctt aagaacagtg ctaaatattt gtatgtcaga
     8101 aactgtacct tctacacctg aaccttgaat ataatcacct atattaaatg gcttaaaaaa
     8161 taaaataatc ataccagagc ctaaatttga taatatttct ttaaaagcta aacctatact
     8221 aaatccagca gctcctaaca cagctacaac tgatgtagtt tgtatcccta taatacctaa
     8281 gcttatcaat gatataatag ataacataga tatatatatt ccatatacaa taaaattatt
     8341 tacaccttta ctcattccat atttgattag aaactttgaa accatccttc ttactatttt
     8401 agatatataa atacctatca caaatacaat tattgcatat ataatatttg gtatattatc
     8461 actaaaatta tcgagcatat tttctaaagt tctcttagtt atattgctat ttgttgaggc
     8521 agtcttagcc aatgataaaa aattcattca actcctcctt atgataatat tccgttgtcc
     8581 tttaactctt ttactatagc ttctatagtt tcttctttta ttgcctcaat tgtatgaata
     8641 tggctacatt ctgtcagaac cgataattgt ttaaattcat ttgtctcaac tttcttcata
     8701 aagttgtcta tatccatttt agaataaata ttaagttctg cagttatctg accatatgtt
     8761 ggatgattta cgatgacatc ttttataata ccacctaaat ccacaattat ctttaattca
     8821 tcataaattt ctttagaatc cttatgattt ttacacttta tttgttttgt aaaatacggt
     8881 tgattatata ttatatatcc ttgaggtgta gctattattt caaatcctct agctcttata
     8941 agggctatat cttgaactat tacttgccta cttacattta atagttcagc tagtgttcca
     9001 ccttttacag gatgcttaga ttcttttaaa atatctatta atttacttct tctttcatta
     9061 gaattcatat tacaccttct ttccaaataa aaactttacc tatactatat aattttatat
     9121 tttatcttat tataaatcaa tattgacttt atattctatt taatcttaac ttttataata
     9181 aataaaaaag a
//
LOCUS       DAYAOO010000125         8872 bp    DNA     linear   BCT 12-OCT-2024
DEFINITION  TPA_asm: Clostridioides difficile isolate ST8-SSI-h139-18
            SAMN40601845-rid21577343.denovo.129, whole genome shotgun sequence.
ACCESSION   DAYAOO010000125 DAYAOO010000000
VERSION     DAYAOO010000125.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN40601845
            Sequence Read Archive: SRR28438827
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 8872)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8872)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-MAY-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-MAY-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002157583.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002157583.1
            Genome Coverage       :: 163x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/11/2024 16:19:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 4,038
            CDSs (total)                      :: 3,963
            Genes (coding)                    :: 3,930
            CDSs (with protein)               :: 3,930
            Genes (RNA)                       :: 75
            rRNAs                             :: 6, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 60
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 33
            CDSs (without protein)            :: 33
            Pseudo Genes (ambiguous residues) :: 0 of 33
            Pseudo Genes (frameshifted)       :: 7 of 33
            Pseudo Genes (incomplete)         :: 25 of 33
            Pseudo Genes (internal stop)      :: 11 of 33
            Pseudo Genes (multiple problems)  :: 8 of 33
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8872
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN40601845-rid21577343.denovo.129"
                     /isolate="ST8-SSI-h139-18"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Denmark"
                     /collection_date="2018"
                     /collected_by="Statens Serum Institute"
     gene            complement(35..1540)
                     /locus_tag="ACGI5H_003560"
     CDS             complement(35..1540)
                     /locus_tag="ACGI5H_003560"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861375.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000150 - DNA strand exchange activity
                     [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HFG9699245.1"
                     /translation="MNVAIYLRKSRADEEAEHRGEFETLSRHKTTLLKLAREQNLNVI
                     EIKEELVSGESIEYRPKMLELLGEIKNNNYDAVLVMDIDRLGRGNMQDQGLILDTFKK
                     SKTKIITPRKTYDLNDEFDEEYSEFEAFMARKELKLISRRMQRGKIKSIEEGKFIAQA
                     PPYGYDIKYLNNKERVLVINEDKATVVKIIFDMYLKGDGACKISNYLNELGYKTTTGR
                     TWYEKGIRDIIKNKVYCGYIVWNKVERKRNSSRTRGIEEQIEVKGKHEPIISEDIWNK
                     AQNIRKKRINSPTPNNKITNPLAGIVKCGYCNHTLIAKSNTTSNGYEKYMVCTNCKNK
                     ATKLYILENKILEVLNKWLVNYRLSLKDEKDNSKPENTLEHTLINLNKELDTLEKQKE
                     RLHDFLEQGIYDSNTFGERLKILLSRIENAREAINKTNIDIEMQKERNTVKTQIVPQL
                     EKILSEYTEEKEPYLKNILLKSVINYAVYKKEPNQKSDDFSLILYPNIPRD"
     gene            complement(1739..2593)
                     /locus_tag="ACGI5H_003561"
     CDS             complement(1739..2593)
                     /locus_tag="ACGI5H_003561"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428657.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GyrI-like domain-containing protein"
                     /protein_id="HFG9699246.1"
                     /translation="MEWIERLNKAINYIEENITKEIEYEQVAKIACCSTYHFQRMFAY
                     MADVPLSEYIRRRRMSLAAVELQNDDKKIIDVALKYGYSSPTAFNRAFKSIHGVAPSV
                     IKKREITTLKAFPPISFKISIKGAEEMNYRIEKKEAFRIVGVSQPLHNELEKNFEIVP
                     QMWQKVALDGTLQKLIPMMDSQLQGVLGISICNNSEEWKYFISVSSTKSIDNTLEEYT
                     VPAFTWAIFSGEGQCPQAIQELEKRIVTEWLPTSGYEYDNGPDIELYLNPDPQNAKFE
                     VWIPVVKK"
     gene            2978..3259
                     /locus_tag="ACGI5H_003562"
     CDS             2978..3259
                     /locus_tag="ACGI5H_003562"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435514.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9699247.1"
                     /translation="MPNIEKDLDGTTTITYLNDDIGVPTDENGYKISMTILHGKTICH
                     VVSPETILGRKFTLEEKQEKDTIIYGAIEKIMVDRQLQIKNSNKEVASH"
     gene            3409..4257
                     /locus_tag="ACGI5H_003563"
     CDS             3409..4257
                     /locus_tag="ACGI5H_003563"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003442793.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sialate O-acetylesterase"
                     /protein_id="HFG9699248.1"
                     /translation="MIKSFLMLGQSNMAGRGFISEVTPIYNERIQMLRNGRWQMMTEP
                     INYDRPVSGVSLAASFADAWCCENQEDRIGLIPCAEGGSSLDEWNIDGILFKHAISEA
                     KFAIQSSELTGILWHQGENDSNNGNYKFYYKKLLSIIETLRKELNIPDIPIIIGGLGD
                     FLGKVGFGKSCTEYVFINQELQKFAFEQDNCYFVTATGLTSNPDGIHIDAISQRKFGL
                     RYFEAFHKKKHIMEALANESELIIPSNSKTYTKTEKIYINSMDLALGKISYDEFESKL
                     IKLNDN"
     gene            4309..4830
                     /locus_tag="ACGI5H_003564"
     CDS             4309..4830
                     /locus_tag="ACGI5H_003564"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435497.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PadR family transcriptional regulator"
                     /protein_id="HFG9699249.1"
                     /translation="MIPLLILGLLKQNPNSYGYELLALMEKKHYKYIVNFTKGSFYYN
                     LQQLEEKKFIEKVENKQSNKNRETHNYIITELGCQEFEKLMYKYGSKTEYINLSFYAT
                     LLFANDYKNEKLIELLETQIKQTQVRISLLNESIENDKTNSHYFNRMLENSRSHHLVN
                     IEWFEKLLNDIRD"
     gene            5199..5714
                     /locus_tag="ACGI5H_003565"
     CDS             5199..5714
                     /locus_tag="ACGI5H_003565"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902815.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016987 - sigma factor activity [Evidence
                     IEA];
                     GO_process: GO:0006352 - DNA-templated transcription
                     initiation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="RNA polymerase sigma factor"
                     /protein_id="HFG9699250.1"
                     /translation="MNDARIISQIKAGKKELFDTLIKKYYDSIYCYCYRHVDNKMTAQ
                     DLTQDVFVTVINNIENYKHYGKFENYLYVIAKNKCKDFWKKKQPIYLESLDKEISNQE
                     LSDIENKMFIKEALTKLPELEFEVIILRYYHDLRFKDIAKIMESSVSVTKYRMSRALK
                     KLELYLEGGKL"
     gene            5711..6472
                     /locus_tag="ACGI5H_003566"
     CDS             5711..6472
                     /locus_tag="ACGI5H_003566"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729056.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9699251.1"
                     /translation="MNNKEIKRSLQKYKVPKYDSSALEKTIKTIHELTLSNTYKRMNN
                     KDFFISQIGFIRKRTWIMQFLILCTICIFLFSTSADSNSFYNSLSLISIASPLFVLTN
                     IEELTKVYNSSILEIEFSTKNTLHKIIATRMLIFGISDLLFMIIILVSAKQIIDVNIL
                     YIIIYILVPFNLMCIGCMEIINRNKGKHTNYYCMIYGISLVLLIVTLSNFRDNLYQFE
                     AINQWLIVFLVTAVTLIYEIRKTWRHLCSFENIII"
     gene            6510..7376
                     /locus_tag="ACGI5H_003567"
     CDS             6510..7376
                     /locus_tag="ACGI5H_003567"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861379.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HFG9699252.1"
                     /translation="MELSVERLTKQYNNKIIVDKIDFKLNEGIYGFLGENGAGKTTLM
                     RMICGILSPTSGEVKVDGKNNLDMGEDFRDMIGYLPQNFGYYPDFTAKEFMLYIASLK
                     GLMPSYAKRKTQELLEMVGLSEVINKKIRTFSGGMKQRLGFAQTLLNDPKILILDEPT
                     AGLDPKERVRFRNLISEFSKEKIVILSTHIVSDVEYIADKILIMKKGRFVLTGSIEEV
                     TSKIKDKVWKCVVNENEIDYMSDRYCLANIHHSGGVANLRIVSDIKPHDNACNLKPTL
                     EDLYLYCFNEVL"
     gene            7397..8638
                     /locus_tag="ACGI5H_003568"
     CDS             7397..8638
                     /locus_tag="ACGI5H_003568"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428664.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease subunit"
                     /protein_id="HFG9699253.1"
                     /translation="MSTLIKFELKKIIKRKSTIAVILGSLFLSIILFALMPIQEKAND
                     ESGKEYRGLQAIELKKQQSKLNEGYITDKKVKNSIRDYQKMFNNPNNITTDEGGFSNF
                     KPDIYWKFFYPNKAFYNFIIESYSNPNDYNPEIIKSMPLEDGVNFYKFRNEKVNTILN
                     MEYPDKNYTQKEKDFWLSKNKDIEEPYLNGYYQGWNYFLLARDLLIFTIVAVCISTAS
                     VFSGEYQSGADSIILSSKYGKTKVITAKIVSSFLFGTIIFTINTIVSIGILLLSFGID
                     GWNLPLQLTTSSIPYPYTFLQAILLSVLIIYMILILLISFTLLLSSYMKSPFPVLITN
                     IILLFVPIFLKYSETNKLYNQILNVLPSNAISFSFTNYVDYKFGNLIIALPTMIIFTC
                     LVLTVVFLPFIKNNFKKHQVN"
BASE COUNT         3338 a         1085 c         1216 g         3233 t
ORIGIN      
        1 taatcagtct atttataaca tttaaaacat ataattaatc tcttgggata ttagggtaaa
       61 gtattaaaga aaaatcatca gatttttgat taggttcttt tttatagact gcgtaattta
      121 ttacactttt aagcaatata ttttttagat aaggttcttt ttcctctgta tattcactta
      181 aaattttttc aagttgagga acaatttgtg ttttaactgt atttctttcc ttttgcattt
      241 caatatctat atttgtttta ttaatagctt ctcttgcatt ttctatacga gataagagta
      301 tttttaaacg ttccccaaat gtattactgt cataaattcc ttgttctaaa aaatcatgta
      361 gtcgttcttt ttgtttttct aaagtatcca attctttatt taaatttatc aaggtatgtt
      421 ctaaagtatt ttcaggttta gagttgtctt tttcatcttt taaagatagt ctataattta
      481 ctaaccattt atttaagacc tctaatattt tattttctaa tatgtatagt ttagtagctt
      541 tatttttaca attagtacaa accatatatt tctcatatcc atttgatgta gtattagatt
      601 tggctattaa agtatgatta cagtatccac attttacaat tccagccaat ggatttgtta
      661 ttttattgtt tggagtaggg gaattaatac gtttttttct tatattttgt gccttattcc
      721 atatgtcttc acttattatt ggttcatgct ttccttttac ctcaatttgt tcctcaattc
      781 ctcttgttct actagaattt cttttcctct cgactttatt ccatactata tatccacaat
      841 acactttgtt ttttataata tctcttatac ccttttcata ccaagttcta cctgttgtgg
      901 tcttataacc aagttcgttt aaataattgg atattttaca tgcaccatct ccttttaaat
      961 acatatcaaa gattatttta acaacagttg ctttatcttc atttattaca agtactcttt
     1021 ctttattatt taaatattta atatcatacc cataaggagg agcttgagct ataaatttac
     1081 cctcttcaat acttttgatt tttcctcttt gcatacgtct agatattaat tttaattcct
     1141 tacgagccat aaaagcttca aattcagaat actcctcatc aaactcatca tttaaatcat
     1201 acgtttttct aggagtaata attttcgttt tagatttttt aaatgtatct agtattaacc
     1261 cttggtcttg catattacca cgacccaaac ggtcaatatc catcactaaa acagcatcat
     1321 agttattatt tttaatttca cctagtaatt ctagcatctt aggtctatat tctatacttt
     1381 ccccagaaac aagttcttct ttaatttcaa tgacatttaa attttgttct cttgctagtt
     1441 ttaaaagagt tgtcttatgt ctacttagag tttcaaattc acctctatgt tctgcttctt
     1501 catcagctct gcttttgcgt aaataaattg ccacattcat taaatcacac cccttgaata
     1561 tattatattc agtaacagat tgattatatt taaaacacaa aaataaacct tcaaaataca
     1621 agatatattt tttaggttta tttttataca gtaaatttta tagtatattt aaaagcttgt
     1681 aatctaagta aatatttata ctattaattt tatgctttct tcatttttta attttaaact
     1741 atttttttac tacaggtatc catacttcaa atttagcatt ttgagggtct ggatttaagt
     1801 acagttcaat atcaggacca ttatcatatt cataaccaga agtaggtaac cattctgtta
     1861 caatacgctt ttctagttct tgtattgctt gtggacattg tccttctcca gaaaatattg
     1921 cccaagtaaa agctggaaca gtgtattctt ctaatgtatt atctatagat tttgtacttg
     1981 aaacagatat aaaatacttc cattcttctg aattattaca aatacttata cctaatacac
     2041 cttgaagttg actatccatc atagggatta atttttgaag cgttccatct aaagcaacct
     2101 tttgccacat ttggggaaca atttcaaaat tcttttctag ttcattatga agtggctgag
     2161 atacaccaac tatacgaaat gcttctttct tttcaattct ataattcatt tcttcggctc
     2221 ctttaatact aattttaaaa ctgattggag gaaaggcttt taaagttgtt atttctcttt
     2281 tttttataac tgatggggca acaccatgaa tacttttaaa tgcacgattg aatgctgttg
     2341 gagaagagta tccatatttt aaagccacat caattatctt tttatcatca ttttgtaatt
     2401 ctacagctgc taaagacatc cgtctacgac gaatatattc agaaagtggt acatctgcca
     2461 tataagcaaa cattctttga aaatgatatg tagaacaaca agctattttt gccacttgtt
     2521 catactcaat ttcttttgtt atgttttctt caatatagtt aattgctttg tttaatcttt
     2581 caatccattc cataaaatca gctccttgta atttatataa tatctatttt aaaatagtta
     2641 atcctctctt tctatgcact aattaactag cttaataaag aatgaacatg agaaagtctg
     2701 taattaacta caaaaatgaa caaatagtat tgtttttcac attaaagtat atcacaaatt
     2761 agtatctaat ttttatataa gataacagtt ttaatttatt atgaaatttt tataatattt
     2821 tagcttagac atttaattat atataacatt ttatttatag ttaactattt ttgaagttta
     2881 cccttaatca agcaacactt agttattcaa ttataaataa tgattgagaa taggacaatt
     2941 tttaagatac ataaaatata aagaggaggg gatttaaatg ccaaacatag aaaaagactt
     3001 agatggtaca actactataa catacctcaa cgacgatata ggtgttccaa cagacgagaa
     3061 tggatataaa atatctatga caatactaca tggaaagaca atctgccatg tagtatctcc
     3121 tgaaacaatc ttaggaagaa agttcacatt agaagaaaaa caagaaaaag atacaataat
     3181 atatggagca atagaaaaaa taatggtaga cagacaatta caaataaaaa attcaaacaa
     3241 agaagttgct agtcattagc acttctttaa taagtaaagt aggacaagta ttttttataa
     3301 tattattgac ttatagtcta attagactat aatataaaca tagatagtct aattagacta
     3361 ctattaaaaa taaatacaat aagaatttaa gaaaggataa taataataat gattaaatca
     3421 tttttaatgt taggacagtc caatatggct ggaagaggat tcataagtga agtgactcca
     3481 atttataatg aaagaataca gatgttacgt aatggaagat ggcaaatgat gacagaacct
     3541 attaattatg acagaccagt ttctggggta agtcttgctg catcatttgc agatgcatgg
     3601 tgctgtgaaa atcaagagga tagaattggg ctaattcctt gtgctgaggg aggcagttcc
     3661 ttagatgaat ggaatataga tggtatactt tttaaacatg ctataagtga agctaaattt
     3721 gccatacaaa gcagtgaatt gacaggaatt ttatggcatc agggagaaaa tgacagtaat
     3781 aatggcaact ataaatttta ttataaaaaa ttactttcta ttattgaaac tcttagaaaa
     3841 gaattaaata ttccagatat accaattatt attggtggat tgggagactt cttaggaaaa
     3901 gtaggttttg gaaaaagttg tactgagtat gtatttatca atcaagagtt acagaaattt
     3961 gcttttgaac aagataattg ttactttgtt acagcaacag gtcttacatc taatcctgat
     4021 ggtattcata ttgatgcaat atctcaaaga aaatttggat tacgttattt tgaagctttt
     4081 cataagaaaa agcatattat ggaagcatta gctaatgaaa gtgagttgat aataccgagt
     4141 aattccaaga catatacaaa aacagaaaaa atatatataa atagtatgga cttggcacta
     4201 ggaaagatat catatgatga gtttgaatct aaacttatta aacttaatga taattagata
     4261 aaatattcat taatatacta ataaatatag attgaaagag gtgatttttt gataccatta
     4321 ttaattttag gattattaaa acaaaatcca aattcttatg gatatgagtt attagcatta
     4381 atggaaaaga agcattacaa gtacatagta aatttcacta aaggttcttt ttattataat
     4441 ttacagcaac ttgaagaaaa aaagtttatt gaaaaagttg aaaataaaca atctaataaa
     4501 aatagagaaa ctcataacta cataattact gaacttggat gccaggaatt tgaaaaatta
     4561 atgtataagt atggttctaa aacagagtat ataaatctat cattttacgc aacactatta
     4621 tttgcaaatg attataaaaa tgaaaagtta atagaattat tggaaacgca aattaagcaa
     4681 actcaagtaa gaatttctct attaaatgaa tccatagaaa atgacaaaac aaattcacat
     4741 tattttaata gaatgctaga aaattctcgt tctcaccatt tagttaatat tgaatggttt
     4801 gagaagttgc taaatgatat tagagattga ttttaataat aaaaaaacat acatatatat
     4861 tttatataaa tgtatgatat atagattaaa aataaggcag ataattttca attgaatatc
     4921 tgtctttttg ttatataaga tgttaaaaga aacttatact atgtaagtaa aatttataaa
     4981 tataaagttg ttcattgttg aattacagac acttaagatg aaaagtatga catttgatat
     5041 aataaaattg tttaagtatt aattatgagt attaattaat ggtatagata attttaatat
     5101 aactgtattt ataaataatt ataaaataat aaattaattt ttttatactg acttttttat
     5161 agtataaatc gttatatata atgacggagg tgataatagt gaatgatgct cggattatat
     5221 cacaaataaa agcaggaaaa aaagaattgt ttgatactct aataaaaaaa tactatgata
     5281 gcatctactg ttattgttat cgccatgtag acaataaaat gactgcacaa gatttaactc
     5341 aagatgtatt tgtaacagtt ataaataata tagaaaatta taaacattat ggtaagtttg
     5401 aaaactattt gtatgttatt gcaaaaaaca agtgtaagga tttttggaag aaaaaacaac
     5461 caatatattt agagtcatta gataaggaga tatcaaatca agaattatct gatatagaaa
     5521 ataaaatgtt tataaaagaa gctttgacta aattaccaga attagaattt gaagtgataa
     5581 ttttacggta ttaccatgat ttaagattta aggatattgc taaaattatg gagtcaagcg
     5641 tctctgtcac aaagtacagg atgagtaggg cattaaaaaa actagaatta tatctggaag
     5701 gaggtaaatt atgaataata aagaaataaa aagaagtcta cagaagtata aggttcccaa
     5761 atatgattct tcagctcttg aaaagactat taaaactata catgagttaa cgcttagtaa
     5821 tacttataaa agaatgaata ataaagactt ttttatatct caaattggtt ttataagaaa
     5881 aagaacttgg attatgcaat ttctaatact atgtacaata tgtatatttt tatttagtac
     5941 atcagcagat agtaattcat tttataatag tttatccttg atttctatag catcaccact
     6001 ttttgtactg acaaatatag aagaattaac aaaagtgtat aatagtagta ttttagagat
     6061 agaattttca acaaaaaata cattacataa aattattgct actagaatgc ttatatttgg
     6121 aataagtgat ttattgttta tgattattat tttggtatct gcaaaacaaa tcattgatgt
     6181 aaacattctg tatataataa tttatatact agttcctttt aacctaatgt gtataggatg
     6241 tatggaaatt ataaatagaa ataaaggtaa gcatacaaat tattattgta tgatatacgg
     6301 tatatctctt gtattattaa tagttacact gagtaacttt agagataatc tatatcaatt
     6361 tgaagcaata aatcaatggc taattgtttt tctagtcaca gcagtaacat taatatatga
     6421 aataagaaaa acgtggagac atctttgttc atttgaaaat attattatct aagtaaaaaa
     6481 taagaataca cagtatcagg aggaatagta tggagttaag tgtagaacgt ttaacaaaac
     6541 agtataacaa taaaattata gtagataaaa ttgactttaa attaaatgag ggtatatatg
     6601 gatttttagg agaaaatgga gctggaaaaa caactcttat gagaatgatt tgcggaatat
     6661 taagtcctac atctggagaa gtaaaggtgg atggtaaaaa taatttggat atgggagaag
     6721 attttagaga tatgattgga taccttcctc aaaactttgg atactaccca gattttactg
     6781 ccaaagaatt tatgctatat atagcatcat taaaaggatt aatgcctagc tatgcaaaga
     6841 gaaaaacaca agaattatta gaaatggtag gattatcaga ggtaattaat aaaaaaataa
     6901 gaacattttc tggaggtatg aagcaaaggc taggatttgc tcaaacacta cttaatgacc
     6961 ccaaaatttt aatattagat gagccaacag cagggctaga ccctaaagaa cgagttagat
     7021 ttcgcaacct aatttcagaa ttttctaagg aaaagattgt tatattgtct actcatattg
     7081 tgtctgatgt agaatatatt gcagataaaa ttttaataat gaaaaaagga agatttgttt
     7141 taactggctc aatagaagaa gtaacttcaa agataaaaga taaggtatgg aaatgtgtgg
     7201 tcaatgagaa tgaaatagat tatatgtctg atagatattg tttagcaaat atccatcatt
     7261 ctggtggagt tgcaaatctt agaattgtaa gtgatataaa gccacatgac aatgcatgca
     7321 atttaaaacc aacattagaa gatttatatt tatattgttt caacgaagta ctataaatat
     7381 acataaggag ataggtatgt ctacattaat taaatttgag ttaaaaaaaa taataaaaag
     7441 aaagtctaca atagcagtta ttttaggaag tttattctta agcatcattc tttttgcatt
     7501 aatgccaatt caggaaaaag ctaatgatga aagtggaaaa gagtataggg gtttacaggc
     7561 tattgagcta aaaaagcaac aatctaaatt aaatgaggga tacataacag ataaaaaagt
     7621 aaaaaactca atcagagatt accaaaaaat gtttaataat ccaaataata ttacaacaga
     7681 tgaaggtggg ttttcaaatt ttaaaccaga tatttattgg aaattcttct atccaaataa
     7741 agctttttat aattttataa tagagtcata tagtaatcca aatgattata atccagaaat
     7801 aattaaatca atgcctttag aagatggagt taatttttat aaatttagaa atgaaaaagt
     7861 aaatacaata ttaaatatgg aatatcctga taaaaattac acacagaaag agaaagattt
     7921 ttggttgtct aaaaataagg atatagaaga gccttattta aatggatatt atcaaggatg
     7981 gaattatttt ctattggcta gagatttact aatttttact atagtagctg tctgcataag
     8041 tacagcttct gtattttcag gagaatacca atccggtgct gattcaataa tattatcttc
     8101 taaatatgga aaaacaaaag ttataacagc taaaatagta agttcctttt tatttggtac
     8161 gattattttt acaataaata caattgtgtc tattggtata cttcttttat cttttggaat
     8221 tgatggatgg aatttaccat tacaacttac aaccagttca attccatacc catatacatt
     8281 tttacaggca atattactaa gtgtgttaat tatttatatg atattaatac tattaattag
     8341 ttttacactt ttattatcat cttatatgaa atcacctttt ccagttttaa ttacaaatat
     8401 aatattacta tttgtaccaa tatttttaaa atatagtgaa acaaataagt tgtataatca
     8461 aattctcaat gttttaccat caaatgctat ttcattttca tttactaatt atgtagatta
     8521 taaatttggt aatttaataa tagctttacc tacaatgatt atttttacat gcttagttct
     8581 tacagttgtt tttttacctt ttattaaaaa taattttaaa aaacatcaag ttaactaaaa
     8641 tatatattat aaaaagaagg tgtcttaaaa tgaacttttt agcttattag gcactcttct
     8701 ttgtattaat ttaaatatat tttagtatta gattaaatat gttttcatca ttttaacaat
     8761 gaaaaagagc tttatctcta ttttgagata gctcttataa agttaaatat taaattgata
     8821 actataaaat atgtagtttg aatttataat ttgtgttata atcatactga tt
//
LOCUS       DAYAOO010000126         8523 bp    DNA     linear   BCT 12-OCT-2024
DEFINITION  TPA_asm: Clostridioides difficile isolate ST8-SSI-h139-18
            SAMN40601845-rid21577343.denovo.130, whole genome shotgun sequence.
ACCESSION   DAYAOO010000126 DAYAOO010000000
VERSION     DAYAOO010000126.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN40601845
            Sequence Read Archive: SRR28438827
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 8523)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8523)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-MAY-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-MAY-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002157583.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002157583.1
            Genome Coverage       :: 163x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/11/2024 16:19:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 4,038
            CDSs (total)                      :: 3,963
            Genes (coding)                    :: 3,930
            CDSs (with protein)               :: 3,930
            Genes (RNA)                       :: 75
            rRNAs                             :: 6, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 60
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 33
            CDSs (without protein)            :: 33
            Pseudo Genes (ambiguous residues) :: 0 of 33
            Pseudo Genes (frameshifted)       :: 7 of 33
            Pseudo Genes (incomplete)         :: 25 of 33
            Pseudo Genes (internal stop)      :: 11 of 33
            Pseudo Genes (multiple problems)  :: 8 of 33
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8523
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN40601845-rid21577343.denovo.130"
                     /isolate="ST8-SSI-h139-18"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Denmark"
                     /collection_date="2018"
                     /collected_by="Statens Serum Institute"
     gene            106..300
                     /locus_tag="ACGI5H_003569"
     CDS             106..300
                     /locus_tag="ACGI5H_003569"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889013.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase"
                     /protein_id="HFG9699254.1"
                     /translation="MSVIVMCSRCGKEIDKYRNKYITYYEKNTNAEIKVCINCALDLL
                     EKTRENQELNIQEFQDTIIL"
     gene            complement(402..911)
                     /gene="vanZ1"
                     /locus_tag="ACGI5H_003570"
     CDS             complement(402..911)
                     /gene="vanZ1"
                     /locus_tag="ACGI5H_003570"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889012.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycopeptide resistance protein VanZ1"
                     /protein_id="HFG9699255.1"
                     /translation="MKSRKHNITKGLFIVYIIILTWIILFKLQFDISSLETMNLRSIN
                     LVPFAGSLIINNRVDISEIILNVVIFVPFGIYVCMLKEEWSFIKKVIPIFITSLAFET
                     LQYIFALGASDITDLIGNTLGGIIGIAVFMLLSKIFKNNTIKIINVLALIVTIIVVLF
                     LGLVIFANL"
     gene            complement(1231..1620)
                     /locus_tag="ACGI5H_003571"
     CDS             complement(1231..1620)
                     /locus_tag="ACGI5H_003571"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902377.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0045892 - negative regulation of
                     DNA-templated transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="BlaI/MecI/CopY family transcriptional regulator"
                     /protein_id="HFG9699256.1"
                     /translation="MKINKLPHAELKLMKYIWGVDDVLASRDIIEVMKLKYDWKKSTT
                     LTFLKNLVDKGFLTTDKVDRCTHYTIAIKEKDYLKVETKSFFSFMHNNSFKSFISALH
                     DDEVLDSKSLDKLEEYFKNLKEEDIDD"
     gene            complement(1928..2671)
                     /locus_tag="ACGI5H_003572"
     CDS             complement(1928..2671)
                     /locus_tag="ACGI5H_003572"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9699257.1"
                     /translation="MNSRFKKSATSILSLLAMTILLPASVNASEVENSSMKVTYSEKQ
                     VTDMNKLYDMAKNGITDVKSPNEKGIIKNERTGESMYVDAISTTQLLEVKQSKDLTSK
                     TYSKTVFLDTDTIKPLRKASISEDGWDKTGGVKASGTVTYTISKGDGAFQYISVSKVS
                     GNWSIADGQIRVTNRKVYINQTGFVSNGLGIKQQQRKDPTSNSFSYNAPSSWKPVGRD
                     SLQYNCGFESIATLVRGGSSWSFNFIVQP"
     gene            2819..3202
                     /locus_tag="ACGI5H_003573"
     CDS             2819..3202
                     /locus_tag="ACGI5H_003573"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433385.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9699258.1"
                     /translation="MRKKLFLGIFIVLVIAAIVVLNIKNDKNIFIGESEHWTAKFVTT
                     EEQSELEIKYKDSKDVVKQKFNYSYEFIDGEDAIIILKDAVLESGQEKIIKRQRPGLY
                     SNRESNYKVIISWNKNEETINLKKK"
     gene            3537..4025
                     /locus_tag="ACGI5H_003574"
     CDS             3537..4025
                     /locus_tag="ACGI5H_003574"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9699259.1"
                     /translation="MSLKYWFKNIKKKKQIKKDIKYFKGNKESVINYQEYYTKIYNHY
                     NEIKNINTIRKIEIEQTRIKGQLEKNNNPGNALFFSLIAVVFSLLANLFFSSLNIKDN
                     YINLILQSSSIIVLIFIAINTSLDIAVPYRDEIQFYTTALDVLEDMKKKKLKERKYKK
                     RR"
     gene            complement(4098..4856)
                     /locus_tag="ACGI5H_003575"
     CDS             complement(4098..4856)
                     /locus_tag="ACGI5H_003575"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9699260.1"
                     /translation="MIKINRTRKPIELTEEVQKQLTEEFKNNKEKSVWRKKYITNALL
                     EMSHGKCCYCEMKLIEEGKSLNVEHFHHKDKYPDEVVKWENLLPSCGRCNSEKGTHDT
                     KLEPIINPAINNPKDYLYLYNYRYKSKNRNKLGSDTIDILYLNDTDKLIKPRVNICMA
                     LFKRLESIKTFVEDYQNGTGTHTRRKNKIINEVKGVLRCAQPTEEYSAIVANVIVNDD
                     DYKYIKEIMSEFNLWDNELEELESKAKEIMLDSE"
     gene            complement(4853..6115)
                     /locus_tag="ACGI5H_003576"
     CDS             complement(4853..6115)
                     /locus_tag="ACGI5H_003576"
                     /inference="COORDINATES: protein motif:HMM:NF014516.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HFG9699261.1"
                     /translation="MRKLDNIKKGAIFLDIILDSTNGRDAMKIENIEIKGIGGIKELS
                     LRFNKGLNIICGANGIGKTTILESIAHNFSYANASILKRNKKYDSGTVKMKVVLADEG
                     GISTWFDDEYKIHEFRASKSEMTGHHTYYSKYLLPFKTYRQMEYNQLNSISADKELDG
                     HDLGEISIKGINQVDIKKWLINRFLFYQVENSISEEQKCNFELALKCFEILDGKITFS
                     KILADSLDIMVNTPQGEVYFEYLSSGYKSCFYILLGIIKEIEYRFKDPYIKVEDFEGV
                     ILIDELDLHLHPEWQVKIISALKIVVPNAQIIATTHSPNMIQTLSPNEIIPLIMDENG
                     NVCKKDLELGEYGLQGWTIEEILTDVMGMKTTSSELYLDTMRKFDRAMDKENIDEIKK
                     YYDILMKMLHPKSTLRTILKIQVAGIID"
     gene            complement(6366..7178)
                     /locus_tag="ACGI5H_003577"
     CDS             complement(6366..7178)
                     /locus_tag="ACGI5H_003577"
                     /EC_number="3.5.1.28"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018112536.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008745 - N-acetylmuramoyl-L-alanine
                     amidase activity [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase"
                     /protein_id="HFG9699262.1"
                     /translation="MKICITVGHSILKSGACTSAGGVVNEYQYNKSLAPVLADTFRKE
                     GHKADVIICPEKQFKTKAEEKTYKIPRVNSGGYDLLIELHLNASDGQGKGSEVLYYSN
                     KGLEYATRICNKLGTVFRNRRAKLDKGLYILNSSNPTAVLIESFFCDNKEDYEKAKKL
                     GHEGIAKLIVEGVLNKNINNEGVKQMYKHTIVYDGEVDKIPATVVGWGYNDGKILICD
                     IKDYVPGQTQNLYVIGGGACEKIGSMTKEKFTMIKGNDRFDTLYKALDFIDR"
     gene            complement(7178..7435)
                     /locus_tag="ACGI5H_003578"
     CDS             complement(7178..7435)
                     /locus_tag="ACGI5H_003578"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889440.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phage holin family protein"
                     /protein_id="HFG9699263.1"
                     /translation="MDNLISFIPEQLLILVAALSIIGKGCKKYKQLDNKYIPVVLLIL
                     GIGFSIWMLGLSPVAVLQGVICWGISIGINQTYKQLKEENK"
     gene            complement(7451..7681)
                     /locus_tag="ACGI5H_003579"
     CDS             complement(7451..7681)
                     /locus_tag="ACGI5H_003579"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898415.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hemolysin XhlA family protein"
                     /protein_id="HFG9699264.1"
                     /translation="MNEELFEADLKRHETRINKHGEEIDELKIANIESKAELKALCEN
                     LNSLTSMLKWLIGTMITTLVGFFIFAVQRGIF"
     gene            complement(7713..7850)
                     /locus_tag="ACGI5H_003580"
     CDS             complement(7713..7850)
                     /locus_tag="ACGI5H_003580"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898417.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="XkdX family protein"
                     /protein_id="HFG9699265.1"
                     /translation="MNWYKIITDFYNNGNWTKEQVKTAVEKNKITASEYKEITGEDYI
                     A"
     gene            complement(7851..8150)
                     /locus_tag="ACGI5H_003581"
     CDS             complement(7851..8150)
                     /locus_tag="ACGI5H_003581"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898419.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9699266.1"
                     /translation="MIFLGNLMDTEEQNIKYVCMIHYDSSLLSEEDLKKGTLIDRLPT
                     QKYVENKEAKLFINIDTKEVFYRYTDIKSSIEDKVNSTEQTIADLTFQLMSNGVI"
     gene            complement(8308..>8523)
                     /locus_tag="ACGI5H_003582"
     CDS             complement(8308..>8523)
                     /locus_tag="ACGI5H_003582"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9699267.1"
                     /translation="IKFLNDFVFVSDMSGKIEISNGKISGLVKYDVNLNPIIYADSSR
                     CTNFDIYNGYIYMLYIQTLVALFKKRI"
BASE COUNT         2871 a         1325 c          909 g         3418 t
ORIGIN      
        1 aataaaaagt aaatctaaat ttgatacagt tttaacaatc attattttca gaaaagtgat
       61 actattgaat atattaagaa taattagaga tggaggaact aagatatgag cgtaattgta
      121 atgtgtagtc gttgtggaaa agaaatagat aaatatagaa ataaatatat aacttattat
      181 gagaaaaata ccaatgcaga aattaaagtt tgtataaatt gtgcgttaga tttattagaa
      241 aaaacaagag aaaatcaaga attgaacata caagagtttc aagatacaat aattctttaa
      301 taatttagga aagcacctgt ataggtgctt tttatgtgta aataatttta tatgtaactg
      361 tatcttacgt tctattttaa gctaaacata tatacttatt tctataagtt tgcaaaaata
      421 actaatccta aaaataatac aacaataatt gtcacaatca atgccaatac attgataatt
      481 tttatggtat tattcttaaa tattttcgat aatagcataa aaacagctat tcctatgatt
      541 cctcctagtg tgtttcctat caaatccgtt atatcacttg cacctagtgc aaatatatat
      601 tgaagtgttt caaatgccaa actagttata aaaataggta taactttttt tataaagctc
      661 cattcttctt ttagcataca cacatatatc ccaaatggta caaatataac cacatttaat
      721 ataatctctg atatatctac tctattatta attataagtg acccagcaaa aggtactaag
      781 tttatgcttc taagattcat ggtttcaagg gatgagatat caaattgcaa cttgaatagt
      841 attatccatg ttaaaataat tatgtaaact ataaataatc cttttgtaat attatgtttt
      901 ctagatttca tttattacct ccttactata ttattgtatt attttattaa tacaataata
      961 tagtaaggta atttatctgt caactatttc ttctaaaatt atattccttt tataatttca
     1021 atatctttat catatttaca tgatttaagc tattgtagta tttcatatat ctttaaattt
     1081 taattggtat tattctctat attttttact atcaaacact aaggaaataa tcacttttct
     1141 ttatataatg ttctaccatc acataaaact aacattaaat ccaaacgcta ctctcaattg
     1201 tctcaaacta aaaagatact gatagcttta ttagtcatca atatcttctt ctttcaaatt
     1261 tttaaagtat tcttctaatt tgtccaagct cttactatct aaaacttcat catcatgtag
     1321 tgctgaaata aaactcttaa atgaattgtt atgcataaaa ctaaaaaaac tctttgtctc
     1381 aacttttaag taatctttct cttttatagc tatagtataa tgcgtacatc tatctacctt
     1441 atcagtagtt aaaaagccct tatctactaa attttttaaa aatgtcaatg ttgtgctctt
     1501 tttccaatca tacttcaact tcatgacttc tatgatatct cttgaggcta atacatcatc
     1561 tactccccaa atatacttca ttagttttag ttctgcatgt ggtaatttat taatcttcat
     1621 tagtttacac ctcttaccaa tttatgtata attaaatttt atactaataa tagtatgtaa
     1681 tcaatcagat tggaacaaat ataatattcc aatttattcc atataaaaaa taagcactcc
     1741 ttataataaa gagtgcttta gtatatattc aagcatttat ctaatacaat tatagcatgt
     1801 cttatgtttt agtatgataa ttttcgttcg ttttattatt acaacttata ctatatagtt
     1861 ttatttttta ttatatcttt atggtgtcaa tatatcttta attttaataa aattcactta
     1921 aaatgtttta aggttgaacg atgaaattga atgaccaaga gcttcctcct cttactaatg
     1981 ttgcaattga ttcaaaccca caattgtatt gaagagaatc tctacccact ggtttccaac
     2041 tagaaggtgc attatatgaa aaagaatttg atgttgggtc tttcctttgt tgttgcttaa
     2101 ttcctaatcc attagaaaca aatccagttt ggtttatgta cacctttcta tttgttacac
     2161 gaatctgacc atctgcaata gaccagtttc cagaaacttt actgacagaa atatattgga
     2221 atgctccatc tccttttgat attgtatatg taactgtacc agatgctttt acaccaccag
     2281 ttttatccca tccgtcttct gatatacttg cttttctaag gggctttatt gtatcagtat
     2341 ctaaaaaaac tgttttagaa tatgtcttag atgttaaatc tttagattgt ttgacttcta
     2401 ataattgtgt tgttgatata gcatcaacat acatagattc tcctgttctt tcatttttga
     2461 ttataccttt ttcgttggga cttttaacat cagtgattcc atttttagcc atatcatata
     2521 acttgttcat atctgttact tgtttctctg aatatgttac tttcatagat gaattttcta
     2581 cttcactagc atttacactt gctggtaata gtattgtcat tgcaagtaaa gataaaatac
     2641 ttgttgcaga ttttttaaac ctagaattca tactaatccc tcctttttta ttaattatac
     2701 cacatattct atcatgatag aatataaata tcaaaaaaat tcagaaaatt cataataatg
     2761 atgttagata actgttttca tgttataata catataatta ttcaaaggag ggctcagtat
     2821 gagaaaaaaa ctttttctag gtatttttat agttttagta atcgctgcga tagttgtact
     2881 taatataaaa aatgataaaa atatctttat tggagaatca gaacattgga cagctaaatt
     2941 tgttactact gaagaacaat cagaattaga aataaaatat aaagacagta aagatgtagt
     3001 taagcaaaaa tttaattatt catatgagtt tatagatggt gaagatgcaa ttataatttt
     3061 aaaagatgca gttttagaat caggtcaaga aaaaataata aaaagacaaa gaccaggtct
     3121 ttattcaaat agggaatcta attataaagt aattatatct tggaataaaa atgaagaaac
     3181 tataaacttg aaaaagaaat aatagcaata ttattaattt taaaaattga ttattgaaag
     3241 acttatataa aaaggagtgt ttagaaaaat aaaacactcc tttttatata agtctttgaa
     3301 aattatggat gaaatatatc aaagctttat ctttataaat ataaaactta taattttgtc
     3361 tttacaaatt atctagcctt atccattgtt gaccacacat catcagaata aatctctgta
     3421 aatttttctc ttgtatcctg gctctatttt tatttaaaat cgttcgacaa attgctgata
     3481 tatattatta agtgtgttat aaattaaagt atattatatg gatttatgga ggggttatga
     3541 gtttgaaata ttggtttaaa aatataaaaa agaaaaaaca aatcaagaag gatataaaat
     3601 actttaaggg aaataaagaa agtgtaataa attatcaaga atattacaca aaaatttata
     3661 atcattacaa tgaaattaag aatattaata caattagaaa gatagaaatt gagcaaacta
     3721 gaattaaagg tcagttagag aaaaataata atcctggtaa tgcattgttt ttctccctta
     3781 tagctgttgt tttttcatta cttgctaatt tatttttcag ttcattaaat attaaagata
     3841 attatataaa tttaattctg caatcctcat ctataatagt gctcatattt atagctatta
     3901 atacatctct tgatatagct gtgccttaca gagatgaaat acaattttat actactgcat
     3961 tagatgtatt agaagatatg aaaaagaaaa aacttaaaga aagaaagtat aaaaaaagaa
     4021 gatgataaag aaatttttat caccttcttt ttttatactt tcaaatttaa ttgtatctag
     4081 ttattttaat atgtatttca ttctgaatct aacattattt cttttgcttt actttctaat
     4141 tcttctagtt cattatccca caagttaaat tctgacatta tttcttttat gtatttataa
     4201 tcatcatcat ttactataac atttgccaca atagcactat attcttcagt tggttgagcg
     4261 catcttaata caccttttac ttcgtttata attttatttt ttcttcttgt atgtgttcct
     4321 gtaccatttt gataatcttc aacaaatgtt tttatagact ctaacctttt gaataaagcc
     4381 atgcaaatat ttactcttgg tttaattaat ttgtctgtat cattcaaata taatatatca
     4441 attgtatcac taccaagttt atttctattt ttacttttat atctataatt atataaatat
     4501 aaataatctt ttgggttatt tattgcagga tttattatag gttctaattt agtgtcatga
     4561 gtaccctttt cactattgca tctcccacaa gatggcaata aattttccca tttcactact
     4621 tcatcaggat atttgtcttt gtggtgaaaa tgctctacat tcagtgattt gccctcttct
     4681 atcaatttca tttcacaata acaacatttt ccatgagaca tctcaagtag agcatttgta
     4741 atatactttt tcctccacac gcttttttct ttattatttt taaattcttc tgttaattgt
     4801 ttctgaactt cttctgttaa ttcaataggc tttcttgttc tatttatttt tatcaatcta
     4861 ttattcctgc cacttgtatt ttcagtattg ttctaagtgt actctttgga tgtaacattt
     4921 tcatcaaaat atcatagtat ttcttgattt catctatatt ctctttatcc atagctctat
     4981 caaactttct cattgtatct aaatatagct cagaagaagt tgttttcatt cccataacat
     5041 ctgttaatat ttcttcaata gtccatcctt gcaacccata ttcacccagt tctaaatctt
     5101 ttttacatac attaccattt tcatccataa ttaatggtat gatttcattt ggtgataatg
     5161 tttgtatcat attaggactg tgtgttgttg ctataatttg tgcgtttggg actactattt
     5221 ttaaagcact tataattttc acttgccatt ctggatgtaa atgtaaatct aattcatcaa
     5281 ttaatataac accctcaaaa tcctctactt taatatatgg gtccttaaac ctgtattcta
     5341 tttcttttat aatgcctaat aaaatataaa aacatgattt gtaaccagag gataagtatt
     5401 caaaatatac ctccccttga ggcgtattaa ccattatatc taaactatct gcaagaatct
     5461 ttgaaaaagt aattttccca tccaaaattt caaaacattt taaagctaat tcaaaattac
     5521 atttctgttc ttctgaaata gagttctcaa cttgataaaa aaggaatcta ttaataagcc
     5581 atttttttat atcaacttga ttaattccct ttattgaaat ttctcctaaa tcatgaccat
     5641 ctaattcttt atctgcactt atactattta attgattata ttccatttgc ctatacgttt
     5701 taaatggtaa taaatattta ctataataag tatgatgacc agtcatttca gacttgcttg
     5761 ctctaaactc atgaatttta tattcatcat caaaccaagt agaaattcca ccttcatcag
     5821 ctagtactac cttcatttta acagtaccag agtcatattt tttatttctt tttaatattg
     5881 atgcatttgc atatgaaaaa ttatgggcaa ttgattctaa tattgttgtt ttacctatgc
     5941 catttgcacc acatattata ttaagacctt tattaaacct cagacttaat tcttttattc
     6001 caccaatacc tttaatttca atattttcaa ttttcattgc atctctccca tttgtactat
     6061 caagaattat atctaaaaat atagcaccct tcttaatatt atcaagtttt ctcattctat
     6121 tcaatccctt cattctctga tttattcgac aataaaaaag agacagctat cctaatgatt
     6181 aactatctct gattcttgtc atttatttgt tatgatatac ctgttgccat atttattcta
     6241 aagattatta ctaatattaa tataagttta actgtcttaa ttatatcgta tatttatagt
     6301 atatttgtat taaaagtgta tataaaatgt aagcaaagtg taaattgatt ttataaattt
     6361 ttaatctatc tatcaataaa atctaatgct ttgtaaagtg tatcaaatct atcattaccc
     6421 tttatcatag taaatttttc tttagtcata gaaccaatct tctcacatgc tccaccacca
     6481 atgacataaa gattttgcgt ctgacctggc acgtaatctt ttatatcaca tattaatatt
     6541 ttaccatcat tatagcccca accaactaca gttgcaggga ttttgtcaac ttctccatca
     6601 taaactattg tatgtttgta catctgttta actccctcat tatttatatt tttatttaat
     6661 acaccttcta caattaactt agcaatacct tcatgaccta gtttcttagc tttctcataa
     6721 tcttctttat tatcacagaa gaaactttca attaatactg ctgtaggatt tgaactattt
     6781 aagatatata atcctttatc taatttagct cttctatttc taaatactgt acctagctta
     6841 ttacatattc tagttgcata ttctaaacct ttattactat aatatagaac ttctgaacct
     6901 tttccttgac catcacttgc atttagatgt agttctataa gtaaatcata tcctccacta
     6961 ttaactctag gtattttata agtcttttct tctgctttag ttttaaactg cttttcaggg
     7021 catattatta catctgcctt atgaccttct tttctaaatg tatctgctaa tactggtgca
     7081 agagatttat tgtattggta ttcgttaact actccaccag cagaagtgca tgcaccactt
     7141 tttaaaatac tgtgtcctac tgttatacat attttcatta tttattttcc tccttcaact
     7201 gtttgtaagt ttggtttata cctattgata taccccaaca aatcacgcct tgtaagactg
     7261 caacaggact tagtcctaac atccaaatag aaaatcctat accaagtatt aataacacta
     7321 ctggaatata tttgttatct agttgcttat acttcttaca gcccttacct ataatagaga
     7381 gagcagctac taaaattagc aactgctctg gtataaaact tattaaatta tccatctctt
     7441 atcctcctaa ttaaaatatt cctctttgaa ctgcaaatat aaagaatcct acaagtgttg
     7501 taatcattgt accaattagc catttgagca tacttgtaag tgagtttaga ttctcacaca
     7561 atgcttttaa ctctgcttta gattctatat ttgctatttt taattcgtct atttcttctc
     7621 catgcttatt tattcttgtt tcatgtcttt ttaaatctgc ttcgaaaagt tcttcattca
     7681 tgtaagcctc ctaatttttg aattaaaaaa gactatgcta tatagtcctc tcctgttatt
     7741 tctttatatt cacttgctgt tatcttattc ttttctactg ccgttttaac ttgctcttta
     7801 gtccaattac cattattata gaaatctgtt attatcttgt accaattcat ttatatcacc
     7861 ccatttgaca ttaattgaaa tgttaaatct gctattgttt gttctgtaga atttacttta
     7921 tcttctatgc tacttttaat atctgtatat ctataaaaca cttctttagt atctatattt
     7981 ataaataact ttgcttcttt attttctaca tatttttgag ttggtaatct atcaattaaa
     8041 gtaccttttt tcaaatcttc ttctgacaat aaacttgaat cataatgtat catacaaaca
     8101 tattttatat tttgttcttc tgtgtccatt aaatttccta aaaaaatcat aattcctctc
     8161 ctttttcatc tgaataaacc ttttttgata atatatttct gtaaatgcca ccaccaataa
     8221 aaaaaattat attgtttatt ataattatat tttttgttgg ggctacatta taaaatgtgt
     8281 tacaatagtt gattgtttta aaagtattta aatccttttt ttgaaaagag ctactagagt
     8341 ttggatatat aacatatata tatatccatt atatatatca aaatttgtac aacggcttga
     8401 atcagcataa ataatagggt ttaaatttac atcatacttg actaatccgc ttattttacc
     8461 attagatatt tcaatttttc cactcatatc agatacaaaa acaaaatcat ttaaaaactt
     8521 aat
//
LOCUS       DAYAOO010000127         8466 bp    DNA     linear   BCT 12-OCT-2024
DEFINITION  TPA_asm: Clostridioides difficile isolate ST8-SSI-h139-18
            SAMN40601845-rid21577343.denovo.131, whole genome shotgun sequence.
ACCESSION   DAYAOO010000127 DAYAOO010000000
VERSION     DAYAOO010000127.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN40601845
            Sequence Read Archive: SRR28438827
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 8466)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8466)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-MAY-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-MAY-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002157583.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002157583.1
            Genome Coverage       :: 163x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/11/2024 16:19:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 4,038
            CDSs (total)                      :: 3,963
            Genes (coding)                    :: 3,930
            CDSs (with protein)               :: 3,930
            Genes (RNA)                       :: 75
            rRNAs                             :: 6, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 60
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 33
            CDSs (without protein)            :: 33
            Pseudo Genes (ambiguous residues) :: 0 of 33
            Pseudo Genes (frameshifted)       :: 7 of 33
            Pseudo Genes (incomplete)         :: 25 of 33
            Pseudo Genes (internal stop)      :: 11 of 33
            Pseudo Genes (multiple problems)  :: 8 of 33
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8466
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN40601845-rid21577343.denovo.131"
                     /isolate="ST8-SSI-h139-18"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Denmark"
                     /collection_date="2018"
                     /collected_by="Statens Serum Institute"
     gene            237..1223
                     /locus_tag="ACGI5H_003583"
     CDS             237..1223
                     /locus_tag="ACGI5H_003583"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902777.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HFG9699268.1"
                     /translation="MKKITINDIANLAGVSKSTVSRYLNNKDISDSTKEKIKTIIDEY
                     GYEPNAFAQSLRAKKTYFIGIITPCLDSFVKSKIMMAIDEELKELKYTSLIINTNRKI
                     RSEIDSISKLASLKVDGIILIGTEITKEHKNEIEKLDIPIVVVGQKVDGINSIVNDDY
                     GAGYKMGQYIANKGYKNIVYLGVDESDISVGLNRKNGVLNGLKDKGYDAKVFYTDFDQ
                     ETSIQRSGEMLESENPDIIICATDNIAIATMKEINKRGKNIPQDISVAGFGGYDVLSI
                     ISPKLTTIKFENKNAGKVAANTIVNLIQERKEPLLKEIKFELIEGESTINKN"
     gene            1559..3040
                     /locus_tag="ACGI5H_003584"
     CDS             1559..3040
                     /locus_tag="ACGI5H_003584"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896953.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 32 protein"
                     /protein_id="HFG9699269.1"
                     /translation="MYKEPKYRTILESTKEELNKLRNISLNDKYKPLFHIHPQHGLLN
                     DPNGLAYYNGKYHVFYQWYPYDATHGMKHWAYVSSDDFVNWNREDVALIPIESYESHG
                     AYSGNAIEVDGKLHMYYTGNIKYSAEDRYAYQNLAIMNKDGKITKYENNPIVSEIPKG
                     YTGHVRDPKVFKRKDKYFMLLGAQTSDKKGAIIVYESKNSIDWNFKGELNVKNIDEDF
                     GYMWECPDYINIDEKDILIFSPQGVEPKGFDYQNIYNVVYAIGNMDLDNLTFEIDTMK
                     ELEKGFDFYAPQTFIKDSQIILFAWAGMGEVLYPTDKNKWAHCLTVPRKLNIKNNKLL
                     QMPVDELIKLRYDETSGQNTIKNNINIIENDENVYELNINIKNIDSNKFGLELFSSQD
                     EGVKLEFNKLGNIVTLDRSNFKKVFGVEYGTNRKEYINIDENTNIKVLADRSILEIFI
                     NEGEVVFTSRIFAKENSNQIRVYSDKIVEYEYTKFKLKQGIEL"
     gene            3066..4037
                     /locus_tag="ACGI5H_003585"
     CDS             3066..4037
                     /locus_tag="ACGI5H_003585"
                     /EC_number="2.7.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423829.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016301 - kinase activity [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate kinase"
                     /protein_id="HFG9699270.1"
                     /translation="MKKVISIGEALIDFIPNQNGGKLKNVSEFRRVAGGAPANVSAVV
                     AKLGGKSSFISKLGKDAFGDYIIDVLNEVNVNTDYVLRTSKANTGLAFVSLKEDGNRD
                     FSFYRNPSADMLLEADEVKKEWFNNCHILHFCSVDLIDSPMKLAHKKAIEYALESNSI
                     ISFDPNIRLPLWDSEQSCKKAISEFLPFAHIVKISDEELEFITGENDIEKSLHKLFVG
                     NVELVLYTKGKDGVDAYTKKVKGMCKGVKVNAIDTTGAGDSYIGSFLYTLLYKQITLN
                     DIKEMKQETLNEYLEFSNYYAARSTTIKGAISSYATKEEITEFIKNL"
     gene            complement(4293..4895)
                     /locus_tag="ACGI5H_003586"
     CDS             complement(4293..4895)
                     /locus_tag="ACGI5H_003586"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430312.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0009055 - electron transfer activity
                     [Evidence IEA];
                     GO_function: GO:0010181 - FMN binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="flavodoxin family protein"
                     /protein_id="HFG9699271.1"
                     /translation="MEVCILMGSPKKKGNTAAILKPFIEELENYNSNIEVIWLYDCKI
                     EPCIACKKCQDNLFDFGCYCKDDVQKIFKKILMCDLIVFATPIYSWYCTSPMKALLDR
                     LVYGMNKYYGNEKGPTLWAGKPVALITTCGYRPEKGADIWENGMKRYCKHSQLKYIGM
                     LVERDLGKPNFMNKEKEEHSRQFAKQIYYILDNSIEVDNC"
     gene            5176..6387
                     /locus_tag="ACGI5H_003587"
     CDS             5176..6387
                     /locus_tag="ACGI5H_003587"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861341.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal-dependent decarboxylase"
                     /protein_id="HFG9699272.1"
                     /translation="MYSNEDYKFIEENAPCYIYDETNIIEKCKELKNNILGFDFLYSI
                     KTNPYNKIVKSIAEQGFGADASSTNEVMISSECGVSKDDIYYSSPGKTEIDIETVLDK
                     CIIIADSITEIELINKISKKYNQKVKIGIRINPDFTMDDDSAKSSKFGIDIEDMSSVF
                     KMLSMCDYVSVVGIHIHIKSQVLDFEKLGHYYEKCFFIALNLNKSKYINIEFINFGSG
                     LGVAYDNLRENPLNLKELSKLTQKIAFTNSNTLKSRLLIESGRFIVCKSGNYYVKIVD
                     IKVSRGKKYLIVKNGLNGFMRPIISNLIENITCGVELEGQEPLYTSNHAFSLSVLNNL
                     KEEEYVNVVGNLCTSLDVIANNVKLKKANIGDLISISNAGSYSYSLSPLLFSSYEFPK
                     QYYKRKDGYIE"
     gene            6455..6652
                     /locus_tag="ACGI5H_003588"
     CDS             6455..6652
                     /locus_tag="ACGI5H_003588"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423835.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug transporter"
                     /protein_id="HFG9699273.1"
                     /translation="MELWKRNLFVCWIGMFFSSIGMSQIAPILSLYIKQLGVTDVSLI
                     QQYSGIVFGCTFVVAAFFSPI"
     gene            6686..7657
                     /locus_tag="ACGI5H_003589"
     CDS             6686..7657
                     /locus_tag="ACGI5H_003589"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430314.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HFG9699274.1"
                     /translation="MLLRASIGMGIVIFTMAFVQNVYQLLGLRILQGVFTGYATACTT
                     LIATQTDKNHSGWALGTLATASTTGSLIGPTVGGYIESILGLKSTFIITGGLLFVSFI
                     ISILFVVDNFKPKEIKESISIPKEQLNILPNKFLIASIFVTTFITQLALYSIEPIVTI
                     YISQLTNFASNVALIAGLTFSASGLANLLAAQKLGKMSDKIGPQKVLLISLLWAGIIF
                     IPQAFVKTAWQLMLLRFLLGLSVAGLNPSVNSLLKKIAPEEYVGKIFGYNASAQYIGC
                     SSGAFLGGQISAHLGIRTVFFSTSLLLFMNALWMYKFTGLFIKDKTK"
     gene            7844..8221
                     /locus_tag="ACGI5H_003590"
     CDS             7844..8221
                     /locus_tag="ACGI5H_003590"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423847.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0045892 - negative regulation of
                     DNA-templated transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="BlaI/MecI/CopY family transcriptional regulator"
                     /protein_id="HFG9699275.1"
                     /translation="MTISKIPQAELKVMKFIWEKNDTVTSKETIEAMERKYGWKQTTT
                     LTLLSRLVKKHFLSAEKIDRYTHYTIVVGHKEYLSVETKDFLSNIHDNSLQSLISALH
                     DDEVVDKDMLDLFESHFKNLEEE"
BASE COUNT         3448 a          880 c         1357 g         2781 t
ORIGIN      
        1 ttatattata aataaattag agtatttatc aattcatagt agataaaatt gaaattaaat
       61 ataacaacaa aaaatgaaaa ttacaattaa tttaatgtta aagactcaat tatttggatg
      121 tggaatggat agtacaagta gtatataaaa agtattgact ggacaaataa ctatatttta
      181 ttttaaatat ataatataat gtaataaaat atatcaaatg tagaaggtga taacctatga
      241 aaaaaataac aataaatgat attgctaact tggcaggagt atctaaaagt actgtatcaa
      301 gatatctaaa taataaagat atcagtgatt ctactaaaga gaaaataaag acaataatag
      361 atgaatatgg atatgagccg aatgcatttg ctcaaagttt gagagctaaa aaaacatact
      421 ttattggtat tataacaccg tgtttagatt cttttgtaaa atctaaaatt atgatggcaa
      481 tagatgaaga actcaaagaa ttaaaatata catcactaat tattaatact aatagaaaaa
      541 taaggtcaga aatagatagt atatcaaaat tagctagtct aaaagttgat ggaataatac
      601 taattggtac cgaaataact aaagaacata agaatgaaat tgaaaagtta gatataccga
      661 tagttgtagt tggacaaaaa gttgatggta tcaatagcat agtgaatgat gattatggag
      721 caggatataa aatgggtcaa tatattgcta ataaaggtta caaaaacatt gtatatttag
      781 gtgttgatga aagtgatata tcagttggtt taaatagaaa aaatggagta cttaatgggt
      841 taaaagataa agggtatgat gcaaaagtat tttatactga ctttgaccaa gaaacgtcta
      901 tacaaagaag tggagaaatg ctagaaagtg aaaatccaga tataataata tgtgcaactg
      961 ataatatagc aatagcaaca atgaaagaaa tcaataagag aggtaaaaat ataccacaag
     1021 atatatctgt agctggattt gggggatatg atgtattgtc tattataagc cctaaactta
     1081 caacaataaa gtttgaaaat aaaaatgcag gtaaagtagc agcaaatacg atagtaaatt
     1141 taatacaaga aagaaaagaa ccactattaa aggagattaa atttgaatta atagaaggtg
     1201 aaagtacaat aaataaaaat taagatacac attacatata ttagtaatgt gtattttttt
     1261 actaaaaaaa ctataattct aaaaattagg aaaacttttt tgaaagaaat attgcatctg
     1321 aaataaattt atgctaatct ttaattaaac cggtttcgaa accggtttaa ttaaaccgat
     1381 agaatagcaa aatgagtgca aaaataactg attgtaacaa agtatcaaag taattattag
     1441 agtacatagg aataaacaaa atataaaaga tgtagcacat tgtgtaataa gactaagaat
     1501 tgttttagat agcaataata aagcaaatat aaaattataa aagaaaagga ataaaaatat
     1561 gtacaaagag cctaaatata gaaccatatt agaatcgaca aaagaagaat taaataaatt
     1621 aagaaatata tctttaaatg ataaatataa accactattt catatacatc cacaacatgg
     1681 actacttaat gacccaaatg gattagcata ttataatggt aagtatcatg tattttatca
     1741 atggtatcca tatgatgcaa ctcatggaat gaagcattgg gcttatgtaa gttctgatga
     1801 ttttgtaaac tggaatagag aagatgtagc attaatacca atcgaaagtt atgaatctca
     1861 tggagcatat tcaggtaatg cgatagaggt agatggaaaa ttgcatatgt attatacagg
     1921 gaatataaaa tatagtgcag aagatagata tgcatatcaa aacttagcta taatgaacaa
     1981 ggatggtaaa ataactaaat atgaaaataa tccaatagta agtgaaatac caaaaggata
     2041 tacaggacat gtaagagacc caaaagtatt taaaagaaag gataaatact ttatgttact
     2101 tggagcacaa acaagtgata aaaaaggagc tataatagta tatgaatcta aaaactctat
     2161 agattggaat tttaaaggag aattaaatgt aaaaaatata gatgaagatt ttggttacat
     2221 gtgggaatgt ccagattata ttaatataga tgaaaaagat atattaatat tttcaccaca
     2281 aggagtagaa cctaaaggat ttgattatca aaatatatat aatgtagtat atgctattgg
     2341 taatatggat ttagataatt taacatttga aatagataca atgaaagaac tggaaaaagg
     2401 atttgatttc tatgctccac aaacatttat aaaggactca caaataatac tatttgcatg
     2461 ggctggaatg ggagaagttt tataccctac agataaaaac aaatgggcac attgtctaac
     2521 tgttccaaga aaattaaata taaaaaataa taagctattg caaatgccag tagatgaatt
     2581 aattaaatta agatatgatg aaacaagtgg gcaaaatact ataaagaata atattaatat
     2641 tatagaaaat gatgaaaatg tatatgagct taatattaat ataaaaaata ttgacagcaa
     2701 taaatttggg ctggaattat tttcatcaca agatgaaggt gtaaaattag aatttaacaa
     2761 attaggaaac attgtaactt tagacagaag caactttaaa aaagttttcg gtgttgaata
     2821 tggaacaaat agaaaagaat atataaatat tgatgaaaat actaatatca aagtactagc
     2881 ggatagaagt attttagaaa tttttataaa tgaaggagaa gtagtattta ctagtagaat
     2941 atttgctaaa gaaaattcta atcaaataag ggtttatagt gataaaatag tagagtatga
     3001 gtatactaaa tttaaattaa agcaaggtat tgaattataa aaacacatta taaggggtag
     3061 aaaagatgaa aaaagtaatt agcataggag aagctttaat agactttata ccgaatcaaa
     3121 atggtggtaa attaaaaaat gtatcagaat ttagaagagt agcaggagga gctccagcaa
     3181 atgttagtgc tgttgtagca aagcttggag gaaaatcgag ttttatatct aagttaggaa
     3241 aagatgcatt tggtgattat ataatagatg tattaaatga agtaaatgta aatactgatt
     3301 atgtattgag aacaagtaaa gcaaatacag gacttgcttt tgtatcatta aaagaagatg
     3361 gtaatcgtga tttctcattt tatagaaatc caagtgcaga tatgctttta gaagctgatg
     3421 aagttaaaaa agagtggttt aataattgtc atatcctaca tttttgttca gtagatttaa
     3481 tagatagtcc aatgaaatta gcacataaaa aagcaataga atacgcactt gaaagtaata
     3541 gtataataag ctttgaccct aatataagat tacctttatg ggatagtgag caatcttgta
     3601 aaaaggcaat atcagaattt ttaccttttg ctcatattgt taagatatct gatgaagaat
     3661 tagaatttat aacaggagaa aatgatatag aaaaatcatt acataaactc tttgtgggga
     3721 atgttgaact agtattatat acaaaaggaa aagatggagt agatgcatac actaaaaaag
     3781 taaaaggtat gtgtaaaggg gttaaagtaa atgcaataga tacaaccgga gcaggagatt
     3841 cttatatagg ttcattttta tacaccttat tgtataaaca aataacattg aatgatataa
     3901 aagaaatgaa acaagaaacg ttaaatgagt atttagaatt ttctaattat tatgcagctc
     3961 gtagtacaac tattaaaggt gcgataagtt catatgcaac aaaggaagaa ataactgaat
     4021 ttataaaaaa tttatagtag gaatgagtaa taggttttga aggaagtaac atgtaaagag
     4081 tttttaagga tgtttactat gaaaataatt aacatataaa aagcaataaa gaggctgtct
     4141 caaaatagag ataagcctct ttatcattgt tgaaatgata aaaaatattt taattattgt
     4201 tactttttag aagaatatat atcttatttt aaataagcaa attatgtaag atttatttat
     4261 attatcaata ctttacttgg agtattatgt ctttagcagt tatctacttc aattgaatta
     4321 tctaaaatat aataaatttg ttttgcaaat tgacgagaat gttcttcttt ttctttattc
     4381 ataaaattag gtttacctaa atcacgttca acaagcattc ctatatattt taactgtgaa
     4441 tgcttacagt agcgcttcat accattttcc caaatatcag cacccttttc aggtctatat
     4501 ccacatgttg taataagtgc tactggtttt cctgcccata gagtggggcc tttctcatta
     4561 ccatagtatt tattcattcc atacaccaat ctatcaagta gtgctttcat tggagaagtg
     4621 cagtaccaag aataaattgg agtagcaaaa acaattaaat cacacataag aattttcttg
     4681 aaaattttct gaacatcatc tttacaataa catccaaaat caaataagtt atcctgacat
     4741 tttttacaag caatacatgg ctctatttta caatcatata accatattac ttcaatattt
     4801 gaattataat tttctaattc ctcaataaaa ggttttaaaa tagcagcagt attacctttt
     4861 ttcttaggac ttcccataag aatgcatact tccatattga tacctccaca gtattttaaa
     4921 atagttttta gtgcttaata tagttttagg atactatgag aatacgttaa caacaataca
     4981 ctttgtatat ttgtaataaa attgaaacaa attgttttat caataaaagt tggaatgtat
     5041 ctataattaa aaatatttta ggtatgtttt tacatatatg tgtgtagtta actatggtaa
     5101 tttattgtaa aattatctta taggattata attgcttaat ttatgattat atttaaaatc
     5161 ttggaggtaa aaaatatgta ctcaaatgaa gactataaat ttatagaaga aaatgcacca
     5221 tgttatatat atgatgagac taatataatt gaaaaatgta aggaattgaa aaataatatt
     5281 ttaggttttg attttttata ttctataaaa acaaatccat ataacaaaat tgtaaaaagc
     5341 attgcagagc aaggttttgg agcagatgct tcttcaacta atgaagttat gatttcatca
     5401 gaatgtggag tttctaaaga tgatatttat tattcatcac caggcaaaac agagattgat
     5461 atagaaactg ttttagataa atgcataatt attgcagata gtattacaga aatagaactt
     5521 ataaataaga tatctaaaaa gtataatcag aaagttaaaa taggaataag aataaatcct
     5581 gattttacta tggatgatga tagtgctaaa tcaagcaaat ttggtataga tatagaagat
     5641 atgagcagtg tttttaagat gttaagtatg tgtgattatg tatctgtagt tgggattcat
     5701 atacatatta aatctcaggt attggatttt gaaaagttag gacattatta tgaaaaatgt
     5761 ttttttatag ctttaaattt aaataaaagt aagtatatta atattgaatt tataaatttt
     5821 ggtagtggac ttggagtagc ttatgataat cttagagaaa atccacttaa tcttaaagag
     5881 ctttcaaaat taactcaaaa gattgctttt actaattcaa acacactaaa atcaagactt
     5941 cttattgaat caggacgttt catagtttgt aaatcaggta attattatgt taaaattgta
     6001 gatattaaag tatcaagagg gaaaaaatat cttattgtaa aaaatggact taatggattt
     6061 atgagaccta ttatttctaa tttaattgaa aatattactt gtggagtaga attagaaggt
     6121 caagagccat tatatacatc aaatcatgcc ttttctcttt cagtattaaa taatttaaaa
     6181 gaagaagagt atgtaaatgt tgttgggaat ctctgtacat cattagatgt aattgcaaat
     6241 aatgttaaat tgaaaaaagc aaacatagga gatttgattt caattagtaa tgctggaagt
     6301 tactcctatt ctttatcacc gctattattt tcaagttatg aatttcctaa acaatattat
     6361 aaaagaaaag atggatatat tgagtaaaca atagcataaa ttaataaact tagtattatt
     6421 gaaaaaattt aaaatgcagg gggtgtaatt ctatatggaa ttgtggaaaa gaaatttatt
     6481 tgtatgttgg ataggtatgt tttttagttc tatagggatg agccaaatag cacctatact
     6541 ttcattatat attaaacagt tgggggtaac tgatgttagt ttaatacaac agtattcagg
     6601 tatagttttt ggatgtacct ttgtagtagc agcattcttt tcgccaattt gagggaaagc
     6661 tgctgataaa tatggaagaa aatcaatgct tttacgtgca agtattggga tgggaatagt
     6721 tatatttacc atggcgtttg ttcaaaatgt ctatcagtta ttaggattaa gaatacttca
     6781 aggagttttt acgggttatg ctactgcatg tactactctt attgcaacac agacagataa
     6841 aaatcattca ggatgggctt tgggtactct tgcaactgca tcaactactg gctcattaat
     6901 tggtccaaca gtaggaggat atatagaatc aatcttaggt cttaaaagta catttattat
     6961 aacaggagga ttgttgtttg tatcatttat catctctatt ttatttgtag tagataattt
     7021 taaacctaaa gaaataaaag aatcaatttc tatacctaaa gaacaattaa atatattgcc
     7081 aaataaattt ttaattgcat ctatttttgt aaccacattc attactcaac tagctttata
     7141 ctctatagaa ccaattgtaa ccatatatat atcacaactt acaaattttg catcaaatgt
     7201 agctttaata gctggattga cattttctgc atcaggatta gcaaatttat tagcagctca
     7261 aaaacttgga aaaatgtcgg ataaaatagg tcctcaaaaa gtattgttaa tttcactttt
     7321 atgggctggg attatattta taccacaagc ttttgtaaaa actgcatggc aactgatgtt
     7381 gttgagattt ttattagggt tgtcagttgc agggcttaat ccttctgtta acagcttgct
     7441 taaaaaaatt gcaccagaag aatatgtggg aaaaatattt ggatataatg catctgccca
     7501 gtatataggc tgttcatcag gagcattttt agggggacaa atatcagcac atttaggtat
     7561 tagaacagta tttttttcaa caagtttatt gttgtttatg aatgcacttt ggatgtataa
     7621 atttactgga ttgtttatta aagataagac taaataatca tactatttac atttctaatt
     7681 ttatgatgta aaataaatat tttttatgta atttatcata gaattatata aaaaataacc
     7741 ctatggtaaa aattggaaaa tattattatc gacaaaatct ttgacttaaa aactatattg
     7801 cgatagtatt aatttaataa aagtttgaga ggggcgtaag gttatgacaa tttcaaaaat
     7861 accacaagca gaattaaaag ttatgaagtt tatttgggaa aaaaatgata cagtaacatc
     7921 aaaagaaact attgaagcta tggaacgaaa atatggttgg aaacaaacaa ctacattgac
     7981 acttttatca agacttgtta aaaaacattt tttaagtgca gaaaaaatag atagatacac
     8041 tcattataca atagttgttg gacataagga gtatttaagt gttgagacaa aagatttttt
     8101 aagcaatata cacgacaatt ctttacagag tttaatttca gcactacatg atgatgaagt
     8161 tgttgataaa gatatgttgg atttatttga aagtcatttt aaaaatttag aagaagagta
     8221 attatatcag gatagaactc taagaattta attaatctat ggctgaaaac cataaatggt
     8281 attatttaat cagctactca ctattcataa agtaatatta aataggttct ctaattagta
     8341 aaatgcctaa aataattgga atagggagta tcaagttaaa tgataccact tatttaaata
     8401 agaaatgatt tttaaaattt aaaataattt tataacttgt caatattcat taatctaaag
     8461 tattat
//
LOCUS       DAYAOO010000128         8402 bp    DNA     linear   BCT 12-OCT-2024
DEFINITION  TPA_asm: Clostridioides difficile isolate ST8-SSI-h139-18
            SAMN40601845-rid21577343.denovo.132, whole genome shotgun sequence.
ACCESSION   DAYAOO010000128 DAYAOO010000000
VERSION     DAYAOO010000128.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN40601845
            Sequence Read Archive: SRR28438827
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 8402)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8402)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-MAY-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-MAY-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002157583.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002157583.1
            Genome Coverage       :: 163x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/11/2024 16:19:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 4,038
            CDSs (total)                      :: 3,963
            Genes (coding)                    :: 3,930
            CDSs (with protein)               :: 3,930
            Genes (RNA)                       :: 75
            rRNAs                             :: 6, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 60
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 33
            CDSs (without protein)            :: 33
            Pseudo Genes (ambiguous residues) :: 0 of 33
            Pseudo Genes (frameshifted)       :: 7 of 33
            Pseudo Genes (incomplete)         :: 25 of 33
            Pseudo Genes (internal stop)      :: 11 of 33
            Pseudo Genes (multiple problems)  :: 8 of 33
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8402
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN40601845-rid21577343.denovo.132"
                     /isolate="ST8-SSI-h139-18"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Denmark"
                     /collection_date="2018"
                     /collected_by="Statens Serum Institute"
     gene            231..1310
                     /locus_tag="ACGI5H_003591"
     CDS             231..1310
                     /locus_tag="ACGI5H_003591"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895654.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA alkylation repair protein"
                     /protein_id="HFG9699276.1"
                     /translation="MPELLKNMYNRESLYEVAVAIQSVYNSFKVDEFIKSTMDETWNN
                     LELKARCRKISMSLGMYLPEDYKEALSILEKSVTGFYFAFFFPDFVEVYGQDDINWDL
                     SISALERNTEYWSSEFAVRAFIIKDEERMMAQMRKWSKHKSEHVRRLASEGCRPQLPW
                     GQAISKFKKDPTPVLPILEQLKTDTSTYVQKSVANNLNDISKTHPDLVISIVKDWYGK
                     NKSTNWIVKHGCRTLLKKGNRDVLALFGYDDTTSINLQDFTLETTSISIGEDLTFSFN
                     ILAKKATKTRLEYGIDYIKSNGKRNRKIFKISEVSLKENEKKSYMKKHSFADVSVRKH
                     YPGIHSIAIIINGIEKDKLDFELGI"
     gene            1634..2002
                     /locus_tag="ACGI5H_003592"
     CDS             1634..2002
                     /locus_tag="ACGI5H_003592"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728895.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nuclear transport factor 2 family protein"
                     /protein_id="HFG9699277.1"
                     /translation="MNVYSFWNDTLAQDAVKIRKYFHEDAYINWHDTNEHFTLEEFII
                     ANCEYPDKWNGKVERVLEFGNLVITVTHVYAINKSLSFHVVSFISLKDDKIISIDEYW
                     GEDDDVPQWRLDKHIGKPIK"
     gene            2119..2922
                     /locus_tag="ACGI5H_003593"
     CDS             2119..2922
                     /locus_tag="ACGI5H_003593"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888422.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HFG9699278.1"
                     /translation="MEEKYILSDRGKVYYWIKESNSVFAKNLIFLPGLTANHHLFDFQ
                     IQYFSKNHNVLVWDAPAHGKSRPYLDFSYSNLVEELKVILDRQNMKKVVLIGQSAGGF
                     VAQSFIVKYPNMVEGLMMIGTCPYGTDYYSKSDIFWLKQTEWMLKLFPDKLLRNIISK
                     MCGATSEGRRSMLKMLEGYEKKELCHLMYMGFAGFIPEIQDLNIHCPVCLVVGDKDKT
                     GKVRKYNEQWHNKTGYPLHIIKNASHNVNVDKPNELNQIMDIFIKQLNI"
     gene            3314..4204
                     /locus_tag="ACGI5H_003594"
     CDS             3314..4204
                     /locus_tag="ACGI5H_003594"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902047.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="radical SAM protein"
                     /protein_id="HFG9699279.1"
                     /translation="MIESIPAKQILQKVKFDNTRWFGIDYNMNLYRGCSHGCIYCDSR
                     STIYNIENFDKVRYKENVIEILSKELRSKRKKGVVGIGAMSDTYNPFEKQLCITKQAL
                     DLISENHFGVSIDTKSSLVVRDIPILQKIKKNNSAIVKLTITTANDELSKKIEPYVNP
                     SSVRFDAVKELNDSGIFCGILLTPMLPFLTDNKDEIRAIVEKAHKANAKFIYCMYGVT
                     MRSGQREFFYEHLRDISPKLVLKYQKTYGLNYVCTVQNKDSCEKLLREECARYGILTD
                     MKDIIKAYKRSESYTQIKFF"
     gene            4617..5060
                     /locus_tag="ACGI5H_003595"
     CDS             4617..5060
                     /locus_tag="ACGI5H_003595"
                     /EC_number="2.3.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902048.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016747 - acyltransferase activity,
                     transferring groups other than amino-acyl groups [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HFG9699280.1"
                     /translation="MIEIKTIEINKKSRIDLLMLADPCEEMIDKYLNKGTMYALYDNK
                     ELTCIAVVNEISKEICELKNIATYEHFQNMGYASKMIYHLLDVYSKKYSSMVVGTSES
                     GVPFYEKFGFVYSHKIKNFFVDNYPEPIFEGELQCVDMLYLSYNF"
     gene            5232..5402
                     /locus_tag="ACGI5H_003596"
     CDS             5232..5402
                     /locus_tag="ACGI5H_003596"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427864.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9699281.1"
                     /translation="MDSNNNTIKSTVKKGISFGSCLAMIISYTAWKSIPWAIFHGLMS
                     WIYVLYYWVKYA"
     gene            5775..6872
                     /locus_tag="ACGI5H_003597"
     CDS             5775..6872
                     /locus_tag="ACGI5H_003597"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902002.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Rpn family recombination-promoting
                     nuclease/putative transposase"
                     /protein_id="HFG9699282.1"
                     /translation="MKEKLEEKSKIIKTSKEYKRTIIEEKDREWTKKLNDILSRGDFS
                     NEKLDKIKDLIPKEILTSENVGEVVTEDGYAKPEYDEVFKSLFTLNNDYDLLANFIND
                     ILKDAPYANRNIKQFTQIKRIIKVETDPTINYIGEKRPRLDILAEDEERNHINIEMQR
                     ALEEDYLERAEYYLSRVHGRKLEEGKEYKEIGKTVGIHILNHVKYNHIEDYVNCLRLT
                     MDGHPDIYSSKTALYFIELPKIRKSSCIANRVLIWGKLIDNPSHIDIRILSKTDYVIK
                     RALDRLKELGSNEDYLLNLKRGAYIMNKSRNFKEEIFQEGIEKGIAKGKREEKFNIII
                     KLKNKGYNLSEICDIIDDLNKSEVEKVYNQN"
     gene            7077..7565
                     /locus_tag="ACGI5H_003598"
     CDS             7077..7565
                     /locus_tag="ACGI5H_003598"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892711.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3841 domain-containing protein"
                     /protein_id="HFG9699283.1"
                     /translation="MKFYTIQTLEFWNNNKNNKYLSNDYSFILEDFDIPYKWMYSQMT
                     NRIYEFDDSMIWVWTKRPDLRCSGYLEKGKKGVLLEIEISEDNVLLSEFDLWHLPLMD
                     ITVELYEDEQIEKKVSWERIFDLELCSKLNEVNIEDLTLQGVTSKVPLSNVKLIKEFV
                     AK"
     gene            7651..8058
                     /locus_tag="ACGI5H_003599"
     CDS             7651..8058
                     /locus_tag="ACGI5H_003599"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860890.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9699284.1"
                     /translation="MSKQQTGIKSTLISEILGISYCIGATLVNKYFFKGSSIEYLPII
                     IWVLAMGAQWVYNKKYDDLIDEASKCILSRVNDIAIKVLFFSVAIVSIFLVTLDINVS
                     NLNIGMSLLVILFIQSLLKLILFIYFDRKGIYN"
     gene            8059..8277
                     /locus_tag="ACGI5H_003600"
     CDS             8059..8277
                     /locus_tag="ACGI5H_003600"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860891.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HFG9699285.1"
                     /translation="MSVLLKTKIKSYREKNLMTQGELAKSVGVRRETIVHLENGRYNP
                     SLKLAMDIAKVFDTTVEELFEFIEENNI"
BASE COUNT         3287 a          840 c         1486 g         2789 t
ORIGIN      
        1 cagtaaagta taaaattcta ttactataat aaaagataga actagaagtc tttatgaaag
       61 tgggaaaagt atttatataa ataaattcat atagtttata gtttaatagt aggaaatatc
      121 gtatgagtaa gaatattgta ttttacataa agatttagca atatgacaca ctgttgtcgt
      181 gttctgtagg atatgattaa taaatcagat atgaaaggag agtgagtaat atgccagaat
      241 tactaaaaaa tatgtataat cgtgagtcac tttatgaagt tgcagtagct atccaatcag
      301 tttacaactc atttaaggta gacgagttca taaaatctac aatggatgag acatggaata
      361 acttagaatt aaaagccaga tgtcgaaaga taagcatgag tttaggaatg tatttaccag
      421 aagactataa ggaagctctt tccattcttg aaaaatcagt tacaggtttt tattttgctt
      481 ttttctttcc agattttgtt gaagtttatg ggcaggacga cataaattgg gatttatcta
      541 taagtgcatt agaaagaaat actgagtatt ggtcttcaga atttgctgta agagccttta
      601 tcatcaagga cgaagagcgt atgatggcac agatgcgtaa atggtctaag cataagagcg
      661 aacatgtacg aagacttgca agtgaaggct gtcgtcccca gttgccttgg ggacaagcaa
      721 tatccaaatt taaaaaagac cctacacccg tactgcctat attggagcaa cttaaaacag
      781 atacatcaac gtatgtacaa aagagtgttg ctaataatct aaatgatatc tcaaaaacac
      841 atccagattt agtcataagc attgtaaagg attggtacgg taaaaataaa tccactaact
      901 ggattgtaaa gcatggttgc agaactctac taaaaaaagg caatcgtgat gtattagccc
      961 tttttggata tgatgatact acttctataa atcttcagga ctttacttta gaaacaacgt
     1021 ctatttctat tggagaggat ttaacttttt catttaatat tttagcaaaa aaagcgacaa
     1081 aaacaaggct cgagtacgga attgattata ttaaatctaa tggaaaaagg aataggaaga
     1141 tatttaaaat atcggaggtt tcattaaaag aaaatgagaa aaagtcatat atgaaaaaac
     1201 attcatttgc agatgtaagt gtaaggaaac attatccagg tatacactcg attgctatta
     1261 ttattaatgg tatagaaaaa gataaacttg attttgaatt aggtatataa ttttactaac
     1321 agaataatct atatcagata ctttgctaaa cttatataat atattttact aaatttatat
     1381 taggtagttt actacttgtt tactgaattt aaatacaaag aaatacaggt gctaatccct
     1441 gcccattaaa ggaatatgag cataacacaa aagtagaact tatcaattct gttacgggta
     1501 tagtagtaaa tccatagaat cacaattaga agatgaagtg taaaaaataa gttagtgttg
     1561 attttagttg ctagtgatat tgaatagtta tacaatagcc atataaatta gaatttgtag
     1621 aggagaaata taaatgaatg tatatagttt ttggaatgac actttggcac aagatgctgt
     1681 taagataaga aaatattttc atgaagatgc ttatattaat tggcatgata caaatgagca
     1741 ttttacttta gaagaattta ttattgcaaa ttgtgagtat cctgataaat ggaatggtaa
     1801 agtagaaagg gtgctagaat ttggaaattt agtaattaca gtgacacatg tttatgcaat
     1861 aaataaatca ctatcatttc atgtcgtttc atttatcagc cttaaagatg ataagattat
     1921 ttctattgat gaatattggg gagaggatga tgatgtgcca cagtggagat tagataaaca
     1981 tattggaaag ccaataaaat agtgtttgtt ctgttttata actgaaattt tgataacatt
     2041 tgatattttg atttgtcatt ggtcaacata gtcgttagtg taataattta aaaaagtaga
     2101 atttggagag tgaacactat ggaagaaaaa tacatcttat ctgaccgagg gaaagtatat
     2161 tattggataa aagaaagtaa tagtgtgttt gcaaagaact taattttttt gccaggacta
     2221 acagcaaatc atcatctttt tgatttccag atacagtact tttcaaaaaa tcataatgta
     2281 ttggtatggg acgctcctgc tcatggaaaa tcaagacctt acttagattt ctcatattct
     2341 aacttggtag aagaattgaa agtaatttta gatagacaaa atatgaaaaa ggttgtactt
     2401 atagggcaat cggcaggggg atttgtggca cagtccttta ttgtaaaata tccaaatatg
     2461 gtagaaggac taatgatgat tggaacttgt ccatatggaa ctgactatta tagtaagtca
     2521 gatattttct ggttaaaaca gactgaatgg atgttaaagt tattcccaga taaattgttg
     2581 cgaaacataa tatctaagat gtgtggagct acgtctgaag gcagaaggag tatgctgaaa
     2641 atgttagaag gttacgaaaa aaaagaactg tgtcatctca tgtatatggg atttgctggg
     2701 ttcataccag aaattcaaga cttaaatata cattgtccag tttgtttggt ggttggagat
     2761 aaagacaaga cgggtaaagt gagaaaatat aatgagcagt ggcacaataa gactgggtat
     2821 ccattgcaca ttataaaaaa tgcttcacat aatgtaaatg tcgataaacc taatgaacta
     2881 aatcagatta tggatatatt tattaagcaa ttaaatatat aaaaactaca tactcattag
     2941 gtaaattatg tagtatatgt gtttacagat ggttatagaa ataaatatgt aataaactac
     3001 ttaacactta aaaagtggat ttgtccagag cataatacaa agcatgatat atataaattt
     3061 ttaagcgaaa tacatcaaaa gaaggattag aattagtgga gacagaacag ctattataga
     3121 ttataaataa atagttttaa aggagaggta ctacgaatat agaggaaggt aaatcatacg
     3181 ttattcaagt attataaatg attagtttaa aagtactatc ggataggagt ctccatattt
     3241 aaaccttagt aaaggtagtt aaagtagtag tttaaaaact aaaaaattat ataaaggaat
     3301 taggtataag aaaatgattg agagtatacc agcaaaacaa attttacaaa aagtgaaatt
     3361 tgacaataca agatggtttg gaattgacta taatatgaat ctctatcgtg gttgttctca
     3421 tggatgtata tattgtgata gccgtagcac aatatacaac atagagaatt ttgacaaagt
     3481 tagatataaa gaaaatgtga tagaaatttt aagtaaagaa ttgcgttcaa aaagaaaaaa
     3541 aggtgtagta ggcattggag ctatgtctga cacatataat ccttttgaaa agcaactttg
     3601 tattacaaag caagcactag atttgatttc ggaaaatcat tttggagtgt ctattgatac
     3661 taaaagtagt ttggtggtta gagatatacc gattttgcag aaaattaaaa aaaataattc
     3721 tgctattgta aagttgacta taaccactgc aaatgatgaa ttatcaaaga aaatagaacc
     3781 ttatgtaaat ccaagttctg tacgatttga cgcagtgaaa gaacttaatg attctggaat
     3841 tttttgtggc atattattga ctcctatgct tccatttttg actgataata aagatgaaat
     3901 acgagcaatt gtagaaaaag cacacaaggc taatgcaaaa tttatttatt gcatgtatgg
     3961 tgtaacaatg cgtagtggtc agagagagtt tttttatgag catttaagag atatatcacc
     4021 aaaattggta cttaaatatc agaaaacata tggtttaaac tatgtatgta ctgtacaaaa
     4081 taaagattct tgtgagaagt tgttaagaga agaatgtgca cgttatggta ttttgacgga
     4141 tatgaaagat attataaaag cgtacaagag gtcggagtca tatactcaaa taaaattttt
     4201 ttaagatagg ctttggatga gatataatag tgttgattga tgtgttgata ttatagttga
     4261 ttgttagaga ggatattata gatgaatatt agtattgata ttttaggtaa ttgttagagc
     4321 tgatattata gatgaatatt agtattgata ttctaggtaa ttgctagagt tagtattata
     4381 gatgaatatt agtattgata ctctaggtaa ttgctagagt tagtattata gatgaatatt
     4441 agtattgata ttctaggtaa ttgctagagc tgatattata atttattatt agtattaata
     4501 ttctagggaa ttatcactat attttaaaaa gtaaaaatat atatcaaaat gaattaaata
     4561 agtactgtaa gaagtttgtt aaattaaggt ttgaataaag tgagggtgga gaacttatga
     4621 tagaaataaa aactatagaa ataaataaaa aaagtcgaat tgacctttta atgttagccg
     4681 acccatgtga agaaatgatt gataaatatc tcaataaagg aactatgtac gcattgtatg
     4741 ataataaaga acttacttgt atagcagttg taaatgaaat ttccaaagaa atatgtgaat
     4801 taaaaaacat tgctacatat gagcattttc aaaatatggg ttatgcctca aagatgattt
     4861 atcatctttt agatgtttat agtaaaaaat attcatcaat ggttgttggt acatctgaaa
     4921 gcggagttcc tttttatgag aagtttggat ttgtttattc acataaaatt aaaaactttt
     4981 ttgtagataa ttatccagaa ccaatctttg aaggagaatt acaatgtgtt gacatgttgt
     5041 atctatcata taacttttag ataggataat atttttaggt taatataatt aattaattca
     5101 tataattatc ggaattataa tttataaatt atgtataata agagtataat ttatttagaa
     5161 gctgttatat tgtattatat tcaaataaga tatataataa cttgtttatt ttgaattttg
     5221 gaggattaat tatggattca aataataata ctataaaatc aactgttaaa aagggtattt
     5281 cttttggttc ttgtttagca atgattattt cttatactgc atggaaatct attccatggg
     5341 ctatttttca tggcttaatg agttggatat atgtacttta ttattgggtt aagtatgcat
     5401 agattaaatt aataaataag tatgtaatat tgtaaagttt aagaaacaaa atgtaaggga
     5461 gtgtctcgaa gtgaactttt agtttataag gcactctttt ttgtattaaa taaaatatat
     5521 tttcattatt taaacaatga aaaagatgag tatctctatt ttaatacata cccttatatt
     5581 cattcattta tcaacaatag ttttaaaaag aaagctatct aaaatctatt gtaatctaag
     5641 tgcttctctt taaagtctta actttagtaa tgatatataa gtttataagg ttcttatttc
     5701 aataatgcaa attttactta gaagttcaga ctttggtatg aagaaatggg taataataaa
     5761 aaagaggtgt tgatatgaaa gaaaaattag aagaaaaatc taagattatt aaaacatcaa
     5821 aagagtataa acgaactata attgaagaaa aggacagaga atggaccaaa aaattaaatg
     5881 acatacttag tagaggtgat ttttctaatg aaaaattaga taaaatcaag gatttaattc
     5941 caaaagaaat attgactagt gaaaatgttg gagaagttgt aactgaagat gggtatgcta
     6001 agcctgagta tgatgaggta tttaaatcat tgtttacttt aaataatgat tacgatttac
     6061 ttgcaaattt tataaatgat atcctcaaag atgctccata tgctaatagg aatatcaaac
     6121 agttcactca aataaaaaga ataattaagg ttgaaaccga cccaacaatt aattacattg
     6181 gtgagaaaag acctagactt gatattttgg ctgaagatga agaacgtaac catataaata
     6241 ttgagatgca aagagctctt gaagaggatt atttggaaag agctgaatat tatcttagtc
     6301 gtgtacatgg tagaaagtta gaagaaggta aagaatataa agaaattgga aaaactgttg
     6361 gaatacatat actaaatcat gtaaaatata atcacataga agattatgta aattgcctga
     6421 gattaacaat ggacgggcat ccagatattt attctagtaa aactgcatta tattttatag
     6481 aacttccaaa aattcgtaaa tccagttgta tagcaaacag agttctaata tggggtaaac
     6541 ttattgataa tccttctcat atagatatta gaatactatc taaaacggat tatgttatta
     6601 aaagagcact tgatagatta aaagaattag gtagtaatga ggactattta ttaaatttaa
     6661 agagaggtgc gtatattatg aataaaagta gaaattttaa agaagaaatt tttcaagaag
     6721 gtattgaaaa aggtattgca aaagggaaaa gagaagagaa atttaatatc atcataaaat
     6781 taaaaaataa aggatacaat ttgagtgaaa tatgcgatat tatagatgat ttgaataaat
     6841 cagaggttga aaaagtctat aatcaaaact aatactatga ttgagatggc actagataaa
     6901 tacaaagctt cctcttttaa atttaaatta atataaaact ttgttattta aatatggtag
     6961 atataaagag atatataaat aataggtaca aagaggtgta taaataaagg agataattca
     7021 aaataaaagt ttgaaccatc tccttcttat agaaaaacaa aggggttgat ttatatatga
     7081 aattttatac tatacagact ttagaatttt ggaataacaa taaaaacaat aaatatctat
     7141 caaatgatta ttcttttata ttagaagact ttgatattcc atacaaatgg atgtatagtc
     7201 aaatgacaaa tagaatatat gaatttgatg atagtatgat atgggtttgg acgaagagac
     7261 ctgatttaag atgtagtggt tatttagaaa aaggaaaaaa aggtgtttta cttgaaatag
     7321 aaataagtga agacaatgtg ttattatcag aatttgattt atggcattta cctttaatgg
     7381 atattactgt agagctttat gaagatgaac aaattgaaaa gaaggtaagc tgggaaagaa
     7441 tatttgactt agaactgtgt tcaaaattaa atgaagttaa tatagaagat ttgacattgc
     7501 aaggagtgac atctaaagtg cctctatcta atgtaaaatt aataaaagaa tttgttgcaa
     7561 aataatattt ttattgaaat ttattcaaaa aagttatata tttataacaa gaggtgttat
     7621 aaatacataa ctttttaagg gggattttat atgtctaaac aacaaactgg tattaaatca
     7681 acacttattt cagaaatatt gggaatttct tattgtattg gagctacatt agtaaataag
     7741 tattttttta aaggaagtag tattgaatat cttcctataa ttatttgggt attagctatg
     7801 ggagctcagt gggtctataa taaaaagtat gatgatttaa ttgatgaggc atcaaaatgt
     7861 atactatcaa gagttaatga tattgcaata aaagtattgt ttttttctgt agctatagta
     7921 tctatatttc ttgtaacttt ggacataaat gtgtcaaatt taaatatagg aatgtcttta
     7981 ttagtcattt tgtttattca atccttgttg aagttaattc tatttatata ttttgacaga
     8041 aaggggatat acaattaggt gtcagtatta ctaaagacaa aaattaaatc ctatagagaa
     8101 aagaacctta tgacacaagg tgaacttgca aagtcagtag gagtaagacg tgaaactatt
     8161 gtacatttag aaaatggtcg ctacaatcct tctttaaaac tggcaatgga tattgctaag
     8221 gtatttgata caactgtaga agagttgttt gaatttattg aagaaaataa tatttaaatt
     8281 tcatgtatta cttatgcatt agagaatgaa ttaattatag gtaaaaaacc aagcttatag
     8341 attagagaat aaatgactta tagatgaaaa accaagctca tagattaaag aatgaatgat
     8401 tt
//
LOCUS       DAYAOO010000129         8285 bp    DNA     linear   BCT 12-OCT-2024
DEFINITION  TPA_asm: Clostridioides difficile isolate ST8-SSI-h139-18
            SAMN40601845-rid21577343.denovo.133, whole genome shotgun sequence.
ACCESSION   DAYAOO010000129 DAYAOO010000000
VERSION     DAYAOO010000129.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN40601845
            Sequence Read Archive: SRR28438827
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 8285)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8285)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-MAY-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-MAY-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002157583.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002157583.1
            Genome Coverage       :: 163x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/11/2024 16:19:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 4,038
            CDSs (total)                      :: 3,963
            Genes (coding)                    :: 3,930
            CDSs (with protein)               :: 3,930
            Genes (RNA)                       :: 75
            rRNAs                             :: 6, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 60
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 33
            CDSs (without protein)            :: 33
            Pseudo Genes (ambiguous residues) :: 0 of 33
            Pseudo Genes (frameshifted)       :: 7 of 33
            Pseudo Genes (incomplete)         :: 25 of 33
            Pseudo Genes (internal stop)      :: 11 of 33
            Pseudo Genes (multiple problems)  :: 8 of 33
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8285
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN40601845-rid21577343.denovo.133"
                     /isolate="ST8-SSI-h139-18"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Denmark"
                     /collection_date="2018"
                     /collected_by="Statens Serum Institute"
     gene            <1..572
                     /locus_tag="ACGI5H_003601"
     CDS             <1..572
                     /locus_tag="ACGI5H_003601"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433809.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="class B sortase"
                     /protein_id="HFG9699286.1"
                     /translation="KKLVKILINIICIITLIFSSLSIYIKLSEYKKADEVYTELRENT
                     INNSKHQELYDKNNDYRFWLKINNVNIDYPVVQGYNNDFYLTHDFYKNYLPLGSIFMD
                     YRNNFENDKSLIVYGHYMKNKTMFGQLENYTDEAFFKENNLVEINYKVQTYTYEIFSV
                     YTADLINRDYLSIHFNSNYEFKDYLNYIT"
     gene            complement(1585..2247)
                     /locus_tag="ACGI5H_003602"
     CDS             complement(1585..2247)
                     /locus_tag="ACGI5H_003602"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903509.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HFG9699287.1"
                     /translation="MKMLKVIDIKKIYGKGENEIKAVDGITLEIEPHKFSAIIGQSGS
                     GKSTLLHCMAGLDKPTLGNVFMDNLDLYTLSDEKLSNLRSKEFGFIFQNYNLIPVINV
                     YDNIVLPILIAKGKIDNNYINDLITKLGLESQINKFPNELSGGQQQRVAIARSLANKP
                     SIIFADEPTGNLDSKTTNEVMNLLKYCVNEYKQTLVMITHNDEIAKMADCIITISDGK
                     VI"
     gene            complement(2264..4819)
                     /locus_tag="ACGI5H_003603"
     CDS             complement(2264..4819)
                     /locus_tag="ACGI5H_003603"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433803.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="FtsX-like permease family protein"
                     /protein_id="HFG9699288.1"
                     /translation="MGIYLKMSLAYLKKNKLRTLLLIIGVMLGVMLIFGPSVIKDSQN
                     ENNVVAIHELYSGYHVEFSDLTLDDAKKLETDEKVSKGNSVQNLGRISDKKGNSFILT
                     SSNEEYLKSRYNKIIEGRLPKNNNEIVLEKKALEAMNLSEGVGSTLNLTIKKNYKDTN
                     GSNQLFSINKEFKIVGVMEKPKGYYDVVWQYEAVTYGNDETNNIIPHDAISYNSILSF
                     KSGWRNIEGECDYLMKKYKLGQKSFLPNVPLVRELRYVEDDKNDPNVFKRNVLITTVS
                     IIFIFNIFNITLNQSVKEMGLLRLMGAKKRNIRCMIIYQALIITIIGILLGLVAGVTY
                     SYIGISNYNEVLYSEAGLNPKLYINNEIVIKAILVGMISVFISCIIPTFKIGKISPIE
                     SIINTDKIKNHRSRLGIDRLVSKIFGFYGFMGLKNIGRNKVRAAISMLSIALGGYIFI
                     TTFSSMQEEVNSKIEDMQNRYNITMQFGVNADPQISKYTDSDVENIEKIKGVKSIHKI
                     QITNGMFTFNNKDINKEFTTYNGVEKKEIMEDKLVLKLYDDDYIDEKLNDFVEEGSLD
                     DIKKDTDGYPNVAVYNYFYDIVDDHTIKPIFKELNIGDIITVKIPVEENNTIVYKEMK
                     VRVAVILKDEWIAMGDGDFMPDLEIITSNIHSKNITGEQKYTQLGINLENPYDEIVNN
                     EIQKISRSIPGSLFNSRLSYHEMSESIYKSYIKSQIAIIALVLIIASINIFCTIRTNL
                     LIRKKEISTLRALGVSLKNMKKMLIYEALAYAVFSFIIAMIPSFINLVKFTNWNNDAY
                     INYGIENFMSFTFPIKESLLFFAISVFVCLISVVVSNRDFESMNIIEGIKENE"
     gene            complement(5059..5247)
                     /locus_tag="ACGI5H_003604"
     CDS             complement(5059..5247)
                     /locus_tag="ACGI5H_003604"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898248.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3139 domain-containing protein"
                     /protein_id="HFG9699289.1"
                     /translation="MRKYKAILLTLIISIIAIIGFIIYNNYFRKWNEAEKYIDKYMTY
                     QGVSGDDIERITKEKYTK"
     gene            complement(5259..5438)
                     /locus_tag="ACGI5H_003605"
     CDS             complement(5259..5438)
                     /locus_tag="ACGI5H_003605"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433799.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9699290.1"
                     /translation="MIHIEISEKEFFRKIEEVFDKGEVNVEVDNLGDIKIQVKKFDDK
                     TKSLELKLIKEFKLK"
     gene            complement(5443..5700)
                     /locus_tag="ACGI5H_003606"
     CDS             complement(5443..5700)
                     /locus_tag="ACGI5H_003606"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729170.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9699291.1"
                     /translation="MSKKISESIENSGLRVAENKSDGSFVLSLGNLEYTKEQPSQVLH
                     YSITKEKKDTKEILSIQCVKDFSYNEKLSEDDKFIMAIYNI"
     gene            complement(6080..6286)
                     /locus_tag="ACGI5H_003607"
     CDS             complement(6080..6286)
                     /locus_tag="ACGI5H_003607"
                     /inference="COORDINATES: protein motif:HMM:NF025854.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GHKL domain-containing protein"
                     /protein_id="HFG9699292.1"
                     /translation="MCKYLDNAIEACDKIHDKSIDKYIQIKGTISKSYFVIKCENSKI
                     NSIRKNKSLLLTDKKDKLVHGIGI"
     gene            complement(6462..6707)
                     /locus_tag="ACGI5H_003608"
     CDS             complement(6462..6707)
                     /locus_tag="ACGI5H_003608"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898255.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine kinase"
                     /protein_id="HFG9699293.1"
                     /translation="MIPRLILASSLVIIIVFIKIIKENKLKLQNEVIKNKLDMQYSHY
                     LSIQESHAKVKKLYHDINNHIYCIENLKYKKGKLMGM"
     gene            complement(7347..7670)
                     /locus_tag="ACGI5H_003609"
     CDS             complement(7347..7670)
                     /locus_tag="ACGI5H_003609"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427538.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LytR/AlgR family response regulator
                     transcription factor"
                     /protein_id="HFG9699294.1"
                     /translation="MKKIKINLTHTKSNLAKKYIEVQKKNMLIHTKNKTLDAICILEK
                     IEKDLNIEELVRCHKSYITNLNYVENIKSNTAILDSQEEVPISRYRYKDIKEGFLKFI
                     GDRIC"
     gene            complement(7909..8061)
                     /locus_tag="ACGI5H_003610"
     CDS             complement(7909..8061)
                     /locus_tag="ACGI5H_003610"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898263.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9699295.1"
                     /translation="MKNLNKNTILGEVIITITACDDEKEIQIVIKNQVDNILKNKNKE
                     YRIKKI"
BASE COUNT         2778 a         1201 c          853 g         3453 t
ORIGIN      
        1 tgaaaaaact agtaaaaata ttaataaata ttatttgcat tattacgcta attttctcta
       61 gcctttcgat ttacataaaa ttatctgaat ataaaaaagc tgatgaagta tatacggaac
      121 tcagagaaaa cactatcaat aatagcaaac atcaagaact ttatgataaa aataatgatt
      181 atagattctg gcttaaaata aacaacgtaa atatagacta tcctgtagta caaggatata
      241 acaatgattt ctacctaact catgattttt ataaaaatta tcttccttta ggtagtattt
      301 tcatggatta tagaaataat tttgaaaatg ataagagttt aatagtctat ggtcattata
      361 tgaaaaataa aactatgttt ggtcagctag aaaactatac tgatgaagca tttttcaaag
      421 aaaataactt agtagaaata aattataaag tacaaactta tacttatgaa attttttcag
      481 tatatactgc tgacttaatt aacagagatt atttaagtat acactttaat agtaattatg
      541 agtttaaaga ttatttgaat tatataacct aaaaatcagt acacaaatct gatataaagg
      601 tagatatttc agataaaatt ataactttgt atacttgtaa ctatgaattt aaagatgctc
      661 gtactatagt tcatgctaaa ttaatttcaa aaaaagagac tgataagtag gtttgtgtaa
      721 atgcagactt acctacagtc ttttttgaac gtaaaattag taagtatgga ataatattca
      781 tattaaactt ttgtaggcaa agaaatgaaa aatcaaagag aaataattat tacagattta
      841 gattaccaag ctgaattaag aaagtgtaaa actatggagg atgtagttgg tgaagatagt
      901 atataatagt ttaacttata aattatcttg gtgatattaa tgaagtttca aagtatatat
      961 tatttattga tataaataat attaaatctg ttgctaacag atgtaccttt gtttggagac
     1021 aaactattta agaaatataa ctaaaatgtt gaagtagcta cctgacttta ttttgaaatg
     1081 cgaacaagat tttggcatta agataattta gaaagaatca ctggtacaca aggatgtgaa
     1141 cttagaatga atagaagtat tcaggcataa ggagctttca cccaaataaa acatagtatg
     1201 aactttaaaa gaattctaat cagaggcaat caaaatgttc tttcatagtt tatacctgta
     1261 gtgttagaca tagtatttat aagtttcaca aataagataa tcattaataa atgtagtatg
     1321 tatattcatc ctctcaaaaa tattttttaa tcttacactt tgtaaattat tctattttaa
     1381 aatggtattt ttataccttt atttcttatg accgttttca agctcaaatt ttgcataaat
     1441 ataaattaat gaaaagcaag taaaaaaaga actgtcgcac agcaatttaa aattactcat
     1501 tcgacagtcc ttatttcgtg gatttaaata gtggagaaga atcacaagaa taatacccac
     1561 gattaaacct ttatacaata cattttatat gactttacca tcactaatag ttattataca
     1621 atcagccatc ttagctattt catcattatg agttatcata accaacgtct gcttgtattc
     1681 atttacacaa tactttagta aattcatcac ctcattagtt gttttactgt ctaaatttcc
     1741 agtaggttca tctgcaaaaa ttattgatgg cttattggca agtgatcttg ctattgcaac
     1801 tctttgttgt tgaccacctg ataattcatt aggaaattta ttaatctgac tttctaatcc
     1861 taacttagtt attaaatcat taatataatt attatctatc tttcctttag caattaaaat
     1921 aggaagaact atattatcat aaacattgat aacaggtatt agattatagt tttggaatat
     1981 aaacccaaat tctttacttc taagattaga tagcttttca tcacttaaag tatataaatc
     2041 taaattatcc ataaatacat tacctaaagt tggtttatca agccctgcca tacagtgaag
     2101 taatgtgctt tttccagaac cactttgtcc aattattgca ctaaatttat ggggttctat
     2161 ctctaaagta attccatcaa cagcctttat ttcattttct ccttttccat atattttttt
     2221 aatatctata acttttaaca tcttcataca tttacctccc aaattattca ttctctttta
     2281 taccttcaat aatattcata ctttcaaaat ctctattact tacaactact gatattaaac
     2341 atacaaatac agatatagca aagaatagta aagattcctt aattgggaat gtaaaagaca
     2401 taaaattctc tattccatag tttatatacg catcattatt ccaatttgta aatttaacta
     2461 gatttataaa tgatggaatc atagctatta taaagctaaa aactgcatat gctaatgctt
     2521 catatataag catttttttc atatttttaa gactaacacc taatgctcta agcgttgaaa
     2581 tttctttttt tctaattagt agatttgttc ttatagtaca gaaaatatta attgatgcta
     2641 ttattaaaac tagtgcaatt attgctattt gtgatttaat gtaactttta tatatacttt
     2701 ctgacatttc atgataactt aatctactat taaatagaga ccctggtata cttcttgaaa
     2761 ttttctgtat ctcattatta acaatctcat catatggatt ttctaaattt atgcctaatt
     2821 gagtgtattt ttgttctcct gttatgtttt tagagtgaat attacttgtt ataatttcta
     2881 gatctggcat aaaatcgcca tctcccatag caatccattc atcctttaaa attacagcca
     2941 ctcttacctt catctcttta taaacaattg tattattttc ttcaacagga atttttacag
     3001 ttattatgtc tcctatattt aattctttga atataggctt tatagtatga tcatcaacta
     3061 tatcataaaa ataattatat actgctacat ttggatatcc atcagtgtcc tttttaatat
     3121 catctaagct accttcttca acaaagtcat ttaacttttc atctatataa tcatcatcat
     3181 aaagctttaa aactaattta tcttccatta tctctttttt ttctactcca ttataggttg
     3241 taaattcttt gtttatatcc ttattattaa aagtaaacat tccatttgtt atttgaattt
     3301 tatgtatact tttaacaccc ttaatttttt ctatattctc tacatcacta tctgtgtatt
     3361 ttgatatttg cgggtctgca tttactccaa attgcattgt tatattatat ctattttgca
     3421 tatcttcaat tttactgttg acctcttctt gcatacttga gaatgtagta atgaatatat
     3481 atcctcctaa agcaatagac aacatagata tagcagctct aaccttattt cttccgatat
     3541 ttttaagtcc cataaatcca taaaatccaa atattttgct tactagtctg tctattccaa
     3601 gtctacttct gtgattttta attttgtctg tatttattat tgattcaata ggtgatatct
     3661 tgccgatttt aaaagttggt ataatacaag atataaaaac agaaatcatt ccaaccaata
     3721 tagcttttat aactatttca ttatttatat ataatttagg gttaagacca gcttcactgt
     3781 ataaaacttc gttataatta ctaattccta tatatgaata tgtaacccca gctactaacc
     3841 caagtagtat acctattatt gttataatta atgcttgata gattatcata caccttatgt
     3901 ttcttttctt tgcgcccatc agtctaagca gtcccatttc ttttactgat tgatttagtg
     3961 taatattgaa aatattaaat atgaaaatta tagatactgt agttattaaa acatttcttt
     4021 taaaaacatt cggatcattc ttatcatctt ctacataacg aagttccctt acaagaggta
     4081 catttggtag aaaacttttt tgtcccaact tatatttttt cataagataa tcacattcac
     4141 cttcaatatt tctccatcca cttttaaaac ttaatatact attataacta atcgcatcat
     4201 gaggtataat gttatttgtt tcatcattgc cataagttac tgcttcgtat tgccaaacca
     4261 catcatagta cccttttggt ttttccataa ctcctactat tttaaattct ttatttatag
     4321 aaaataattg attacttccg ttagtatctt tatagttctt ttttattgtt aaatttaatg
     4381 tagatcctac tccttcactt aaattcattg cttctagtgc ttttttctct aatactattt
     4441 cattgttgtt tttaggtagt ctaccttcta ttattttgtt gtatctactt tttagatact
     4501 cttcgtttga tgaagttaat ataaatgagt ttcctttttt atctgaaata cgtcctagat
     4561 tttgtaccga attacccttt gatacttttt catcagtttc taatttttta gcatcatcaa
     4621 gtgtcaaatc actaaactct acatggtatc cactgtaaag ttcatgtatt gctactacat
     4681 tgttttcatt ttgtgaatct tttataacac taggtccaaa tatcaacata acacctaaca
     4741 taactcctat tattaaaagt aatgttctaa gtttattttt ctttaaatat gctagtgaca
     4801 tttttaagta aatccccata taatcctcct attttactat aaattattta tccaactcat
     4861 ctgttaagta gattggtgga tattttaaat cttttaattc ttcattattt tttgaagctt
     4921 actaccatct tcctcatgat aaacttgcag tatcacctta tttacatgta gtgcataata
     4981 atcaccatta taaaaatatt agtatttata acctggataa tttttgtaaa atgatttata
     5041 aagtatccca tcctaattct attttgtata cttttctttt gtaatacgct ctatatcatc
     5101 acctgaaact ccttgatatg tcatatattt atctatatat ttttcagctt cattccattt
     5161 tctaaaatag ttgttgtata taataaatcc tattatggct ataatgctta taattaaagt
     5221 taataaaata gctttgtatt ttctcatagt gaatcttcct acttcaattt aaattcttta
     5281 ataagtttta attctaaaga cttagtttta tcatcaaatt tcttaacttg aatttttata
     5341 tctcccaaat tatcaacctc tacatttact tcacctttat caaatacttc ttcaattttt
     5401 ctaaaaaatt ctttctcact tatttctata tgaatcaatg atctatatgt tataaatggc
     5461 cattatgaat ttatcatctt ctgacagctt ttcattataa gaaaaatctt taacacattg
     5521 aattgataat atttccttcg tatccttctt ttccttagtt attgaataat gtaaaacttg
     5581 gctaggttgt tcttttgtat actccaagtt tcccaaagac aaaacaaaac ttccatctga
     5641 tttattttca gctaccctaa gaccactatt ttctattgat tctgatattt tctttgacaa
     5701 gtcttcttga tactagaaat ctgttcaata gtatatattt tttcatttgt acctgaaacc
     5761 ttatttgtgc atcctgttat taaacctagt gttaagctta tagctataac catagttatt
     5821 gtaatttttt tatcttcata taatcctcct tatatattga aaactcgtta tttctcataa
     5881 aaaaaagacg ctatcttttt ctattaaaag ataacatccc tatatgttta gtatcaatat
     5941 atgttcccca actggtaggt taatcgaccc aactatcaaa attttgattt aatggtatat
     6001 aaatattcaa tataaatttg tcttttttat cttcaaatga taaatctcct ctatattttt
     6061 ttatagaaga tttgatgctt taaatcccta ttccatgtac aagtttatct tttttatctg
     6121 ttaataataa acttttattc tttctaattg aatttatttt actattctca catttaatta
     6181 cgaaatagga ctttgagata gttcctttta tttgtatata tttatcaata cttttatcat
     6241 gtatcttatc gcaagcttct attgcattat ctaagtattt gcaaatatat tagatacatc
     6301 tattggtttt ataaaattca ctttggaaaa attgatatca caaatgaatt taatttttct
     6361 tttttcactt acatcacttt tttcatttat tattatatcc aatataacat tacctgtatt
     6421 gtaaattgat ttaaattctt taatttaatc ttttaaacta tttacatacc catcaatttt
     6481 ccttttttat atttgagatt ttctatacaa tatatatgat tatttatatc atgataaagc
     6541 ttcttaactt tagcgtgtga ttcttgaata cttagataat gagaatactg catatctaac
     6601 ttatttttta ttacttcatt ttgcaatttt aacttatttt ccttaattat ttttataaac
     6661 actataataa tgactaagct actagctagt attaacctag gtatcacaat atacccaact
     6721 atatatattt cctaataccc accaaatcga tacatttttc tatttatata aattattaat
     6781 atagtaaata aatttgttat taaagcaaca gataagtata tatagtttat tttattatct
     6841 ttatctagtc ccaatctttt attaataaat ttaaatatag cacaagctac tatataacta
     6901 ttattataag ataatagtat atatctactt tagcattatc ataactaaac actaatagag
     6961 cttcctctga tgatattaca ttacttgtaa ctacaaaaaa taaatttata gatataacat
     7021 cttttattaa agggtgatat acgtcaaata agaaaaatga aactatatat ttaacaattc
     7081 ctatcttata aaaataatta tagtaagttc ccaagtaata aatatcaaat aatagattat
     7141 atcatataga tttttcttca tattataatc atgggtctta tcaacattaa ataatataat
     7201 gatcttagtt ataagataag ctaataatac agtaaaaaaa gatattttct tagtcttatc
     7261 tgtatcttta tcgtaagtta atatactttt tagtatcatt attggtgtaa acaatgataa
     7321 tattaataat attttattta tatggtttaa catattctat caccaataaa ttttagaaac
     7381 ccctctttta tatctttata tctatatcta ctaataggta cttcttcttg actgtctaat
     7441 attgcagtat ttgactttat attttctaca tagtttaagt tagttatata acttttatga
     7501 catcttacaa gttcctctat atttaaatct ttttctattt tttctaggat acatatagca
     7561 tcaagagttt tattttttgt atgtattagc atgttctttt tttgaacttc tatatatttt
     7621 tttgctagat tagattttgt atgtgttaga tttattttta tttttttcaa tttttttggt
     7681 acatgttaat atgtgttttt ctagttcttg aaaatttatt ggctttaata agtatcaata
     7741 agctcttact tcatatcttt cctgtacata atttattaga gatgttataa atattattat
     7801 ctacttttct tatgtttctt gcgatatcta tactatttag ttctgccatt tttatatcta
     7861 agagtagtgt atcctctcaa ttaactttgt aatgattctt cttttgagct atattttttt
     7921 aattcgatat tctttgtttt tattttttaa tatattatca acttgatttt ttattacgat
     7981 ttgtatttct ttttcatcat cacaagctgt tattgtaatg ataacctctc ctaatattgt
     8041 atttttattt agattcttca ctttaggtta aaacttttta aatgtattta tcaataatat
     8101 ttaaattaaa aatgtataaa aatacctata tccaattgga tataggtatt cgtggatttc
     8161 aatggtggag acgaggggag tctataagtg gttatttgat tgttttgttg ttttttgcaa
     8221 gtgtaggtat atagctattt agttatgatg ttaaactgat tttttcggat attttttatt
     8281 gttta
//
LOCUS       DAYAOO010000130         8095 bp    DNA     linear   BCT 12-OCT-2024
DEFINITION  TPA_asm: Clostridioides difficile isolate ST8-SSI-h139-18
            SAMN40601845-rid21577343.denovo.134, whole genome shotgun sequence.
ACCESSION   DAYAOO010000130 DAYAOO010000000
VERSION     DAYAOO010000130.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN40601845
            Sequence Read Archive: SRR28438827
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 8095)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8095)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-MAY-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-MAY-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002157583.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002157583.1
            Genome Coverage       :: 163x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/11/2024 16:19:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 4,038
            CDSs (total)                      :: 3,963
            Genes (coding)                    :: 3,930
            CDSs (with protein)               :: 3,930
            Genes (RNA)                       :: 75
            rRNAs                             :: 6, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 60
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 33
            CDSs (without protein)            :: 33
            Pseudo Genes (ambiguous residues) :: 0 of 33
            Pseudo Genes (frameshifted)       :: 7 of 33
            Pseudo Genes (incomplete)         :: 25 of 33
            Pseudo Genes (internal stop)      :: 11 of 33
            Pseudo Genes (multiple problems)  :: 8 of 33
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8095
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN40601845-rid21577343.denovo.134"
                     /isolate="ST8-SSI-h139-18"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Denmark"
                     /collection_date="2018"
                     /collected_by="Statens Serum Institute"
     gene            complement(308..1063)
                     /gene="dapB"
                     /locus_tag="ACGI5H_003611"
     CDS             complement(308..1063)
                     /gene="dapB"
                     /locus_tag="ACGI5H_003611"
                     /EC_number="1.17.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422070.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008839 - 4-hydroxy-tetrahydrodipicolinate
                     reductase [Evidence IEA];
                     GO_process: GO:0009089 - lysine biosynthetic process via
                     diaminopimelate [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="4-hydroxy-tetrahydrodipicolinate reductase"
                     /protein_id="HFG9699296.1"
                     /translation="MLKVIISGYNGTMGRVLAECVKKDNELELVCGVARSADEKGHHS
                     DTKLYKTMTDVTEKTDVIIDFSHHETLEPILSYALKNNTPVVLATTGYDENDLNKIEE
                     ASKNIPILLSSNTSLGVNILIKLVKDASKMLEGFDIEIIEKHHNRKEDAPSGTATMIA
                     NAIREVLPESENTHGRYGRDCKRKPNEIGIHSIRGGNIISDHDVVFAGDNEVLTLSHH
                     SQSDEVFANGSIVAAKFLIGKQSGLYKMSDILG"
     gene            1503..2492
                     /locus_tag="ACGI5H_003612"
     CDS             1503..2492
                     /locus_tag="ACGI5H_003612"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018112569.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SPFH domain-containing protein"
                     /protein_id="HFG9699297.1"
                     /translation="MLKEEKTYQEKDAKVFNGVAALIMILLFLVVSIGIMVFGIVKLD
                     SGFTGIGSLMLILGLVFIVVDFILFFGLKMINPKEAIVLVLFGNYYGTIKKEGYYWVN
                     PFCSAINPAVSRINVSKSSSDEKVDISTNSRGKKVSLKTMTLNNEKQKVNDLLGNPII
                     IGVVVIWKVIDATKAVFNVDNYNTFLSIQCDSTIRNVSRLYPYDVSEDGDEKSLRGSS
                     QEIADRLKDELQSRVDIAGIEVCEVRITHLSYAPEIAAAMLQRQQAEAIIAARKKIVE
                     GAVSMVEMALTNLSENNVVTLDEERKAAMVSNLLVVLCGNKDAQPVVNSSSIY"
     gene            complement(2944..3660)
                     /gene="dapD"
                     /locus_tag="ACGI5H_003613"
     CDS             complement(2944..3660)
                     /gene="dapD"
                     /locus_tag="ACGI5H_003613"
                     /EC_number="2.3.1.89"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428057.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0047200 - tetrahydrodipicolinate
                     N-acetyltransferase activity [Evidence IEA];
                     GO_process: GO:0009089 - lysine biosynthetic process via
                     diaminopimelate [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="2,3,4,5-tetrahydropyridine-2,6-dicarboxylate
                     N-acetyltransferase"
                     /protein_id="HFG9699298.1"
                     /translation="MVNLNDAYEIARYIKEVKKKTPVKVYVNTNSLHFQSTDKFKVFG
                     SNGSYIFVGDYEDIMEVLDKHGNDITDTHVEYDRRNSAIPLKNTLSEHARIEPGAIIR
                     DMVTIEKNAVVMMGAVINIGAVIGEGSMVDMNAVIGARGTLGKNVHLGAGAVVAGVLE
                     PPSATPVIVEDDVLIGANAVILEGVRIGKGAVVAAGAVVTTDVEAGAVVAGSPAKVIK
                     MKDEKTADKTKLMEDLRNLD"
     gene            complement(3884..4633)
                     /gene="dapB"
                     /locus_tag="ACGI5H_003614"
     CDS             complement(3884..4633)
                     /gene="dapB"
                     /locus_tag="ACGI5H_003614"
                     /EC_number="1.17.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891682.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008839 - 4-hydroxy-tetrahydrodipicolinate
                     reductase [Evidence IEA];
                     GO_process: GO:0009089 - lysine biosynthetic process via
                     diaminopimelate [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="4-hydroxy-tetrahydrodipicolinate reductase"
                     /protein_id="HFG9699299.1"
                     /translation="MLKVIATGYDGKMGKILADTIREDNELELVCVAARGLDSYEGDL
                     KIYEDMSTIVEEADVVIDFSHHSNLDNILSYVLKTKTPLVIATTGYNDDEMNKIREAA
                     KVIPVFQSYNMSLGVNVLVKLVKDAAKLLEGFDIEIIEKHHNRKVDAPSGTAVMIANA
                     IKEVLPNVENNYGRYGRSAKRQPNEVGIHAIRGGNIVGEHDALFAGDNEVLTISHQAQ
                     SRGIFASGSIAAAKYLVKQKPGFYNMDSMLG"
     gene            complement(4700..5587)
                     /gene="dapA"
                     /locus_tag="ACGI5H_003615"
     CDS             complement(4700..5587)
                     /gene="dapA"
                     /locus_tag="ACGI5H_003615"
                     /EC_number="4.3.3.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422063.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008840 - 4-hydroxy-tetrahydrodipicolinate
                     synthase activity [Evidence IEA];
                     GO_process: GO:0009089 - lysine biosynthetic process via
                     diaminopimelate [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="4-hydroxy-tetrahydrodipicolinate synthase"
                     /protein_id="HFG9699300.1"
                     /translation="MIFKGSAVALVTPFTKDNKVDFDKLGELVEYQIANGTDAIVSCG
                     TTGEANTMTDEEQLATIKYVVEKVNKRVPVIAGSGSNDTMHSVNLSQEAEKLGVDALL
                     IITPYYNKANKAGLKRHFETIANSVKLPIILYNVPGRTCVNISPSLIVELAKIDNIVA
                     VKEASGDLGQVAEIASLVPDDFAIYSGNDDTILPLLSLGGQGVISVLANVCPQETHDL
                     VAKFFEGDIEGSRKLQLGMDALIAALFIEVNPIPVKTAMNLLGFNVGDLRLPLAEMDP
                     ANLEVLKKELVNFGLKVNA"
     gene            complement(5704..6705)
                     /locus_tag="ACGI5H_003616"
     CDS             complement(5704..6705)
                     /locus_tag="ACGI5H_003616"
                     /EC_number="1.2.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438805.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004073 - aspartate-semialdehyde
                     dehydrogenase activity [Evidence IEA];
                     GO_function: GO:0016620 - oxidoreductase activity, acting
                     on the aldehyde or oxo group of donors, NAD or NADP as
                     acceptor [Evidence IEA];
                     GO_function: GO:0051287 - NAD binding [Evidence IEA];
                     GO_process: GO:0008652 - amino acid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate-semialdehyde dehydrogenase"
                     /protein_id="HFG9699301.1"
                     /translation="MKKVNVAIVGATGMVGRTFLKVLEERNFPIENLFLFSSSKSAGS
                     KVMFCGKEYIVEELKETSFTDRGIQIALFSAGGSISEKYAPIAASNGILVVDNSSQWR
                     MNPDVPLVVPEVNPEAIKNHKGIIANPNCSTIQAMVPLKALDDKYKIKRVVYSTYQAV
                     SGSGVKGVEDLEKGMNGNPTGFYPHQISYNCLPHIDSFTENGYTKEEMKMVNETMKIL
                     DNYDLKITATTVRVPVKNGHSESINVEFNNPFELDDLVKTLEEAPGVVVVDNPAKNEY
                     PTAVEFDDRDEVFVGRIRRDFSVDNGVNLWVVADNIRKGAATNAIQIAEMALSYDLV"
     regulatory      complement(6878..7052)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00168"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="Lysine riboswitch is most abundant in Firmicutes
                     and Gammaproteobacteria where they are found upstream of a
                     number of genes involved in lysine biosynthesis, transport
                     and catabolism; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="lysine"
                     /db_xref="RFAM:RF00168"
     gene            complement(7130..8011)
                     /gene="dapA"
                     /locus_tag="ACGI5H_003617"
     CDS             complement(7130..8011)
                     /gene="dapA"
                     /locus_tag="ACGI5H_003617"
                     /EC_number="4.3.3.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008840 - 4-hydroxy-tetrahydrodipicolinate
                     synthase activity [Evidence IEA];
                     GO_process: GO:0009089 - lysine biosynthetic process via
                     diaminopimelate [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="4-hydroxy-tetrahydrodipicolinate synthase"
                     /protein_id="HFG9699302.1"
                     /translation="MLFKGSAVALVTPFTEDNNVNFEKLGELIEYHIENGTDALVVCG
                     TTGEATTMSESEIFAVIKYTVEKVNKRIPVIAGTGSNNTMLSVHMSQEAEKLGVDGLL
                     IITPYYNKTNEKGLKLHFETIANSVKLPIILYNVPGRTKVNIKPSVVAELAKIDNIVA
                     VKEASGDLAQVAEIAKLVPKDFAIYSDNDDTILPLLSLGGSGVISVLANICPKETHDL
                     VTKFFEGDIEGSKKLQLDMDALIAALFIEVNPVPVKTAMNILGFNVGDLRLPLAEMEE
                     TNLNVLKQELTNFGFKF"
BASE COUNT         2785 a         1294 c         1048 g         2968 t
ORIGIN      
        1 taccaataaa ttaggataat atttaatagg tttatatgat gaaaagatta taaaataata
       61 aacaatatga ttccatatac caataaatag gataatattt aataggttta tatgatgaag
      121 agattataaa ataataaaca atataattcc atataccaat aaataagata atctttaaga
      181 aaaatgatta tatttaaaag gtaaacataa aatttataaa cttttagaat agaaatctca
      241 atcaattaga tattcaaatt gatgaatatg aatacctaaa tagattgaga tttattatgt
      301 acaaaactta tcctaatata tctgacattt tataaagccc agattgctta ccaattaaaa
      361 atttagctgc aactatagaa ccgtttgcaa atacttcatc agattgagaa tgatggctta
      421 atgtaagaac ttcattatca cctgcaaata caacatcatg gtcgctgatt atattgccac
      481 ctcttataga gtgtattcca atttcatttg gttttctttt acaatctcta ccatatctac
      541 catgtgtatt ttcactttca ggcaagactt ctctaattgc attagctatc atagtagcag
      601 ttccactagg ggcgtcttct tttctattgt gatgtttttc tatgatttca atatcaaaac
      661 cttctaacat ctttgaagca tccttaacta attttattaa tatattcact ccaagagatg
      721 tatttgatga taataatata ggaatgtttt ttgatgcttc ttctatttta tttaagtcat
      781 tttcatcata tccagtagta gctaatacta caggtgtatt attttttaga gcatatgaca
      841 atattggctc taaagtctca tgatgtgaaa agtctattat tacatcagtt ttttcagtta
      901 catcagtcat tgttttgtaa agctttgtat cactatgatg acctttttca tcagcagacc
      961 tagctacacc acaaaccaac tctaattcat tatctttttt tacacattct gctaaaactc
     1021 ttcccattgt tccattatag ccactaatta taactttcaa cataaattcc tcctatgaaa
     1081 ttaataaaaa tttgttatat ttctataagt ttattttatc actaatataa tttatataaa
     1141 ataatattag tgataataag cttacaattt atcttacatt aaaaaattta agtggatttt
     1201 tcaaaatata gataaatttc tttttcattg tataaatgat aaaaatatat ttgacttcat
     1261 accaaaaaga gtgccccatg aactaaaaag ttaattttga aataccatat tcatatatca
     1321 tatgatttat ttggaaatca atattaatac attaaaataa ctaaatacat gtatgcataa
     1381 agatgtataa aaaatatata aacatatagt attaatttta aattcaacaa tttaattgtt
     1441 aaaagtgtta ttattaaatt agaaatatct taacttaata tactgagatg ggagtgatag
     1501 atatgttaaa agaagaaaaa acttatcaag agaaagacgc aaaagtattc aatggagtgg
     1561 cagctttgat aatgatttta ttatttttag tagtttcaat aggtatcatg gtttttggga
     1621 tagtaaaact tgatagtgga tttactggaa taggttcact tatgttaatt ttgggacttg
     1681 tatttatagt agtagatttt atcctatttt ttgggctaaa aatgattaat cctaaagaag
     1741 ctatagttct agttttgttt ggtaactatt atggaactat aaaaaaagaa gggtactatt
     1801 gggtgaatcc attttgttca gcaataaacc cagcagtatc aagaattaat gtatcgaaat
     1861 cttcatctga tgaaaaggta gatatatcaa ctaattcaag gggcaaaaaa gtatctttaa
     1921 aaacaatgac tcttaataat gaaaagcaga aagtcaatga tttattggga aatccaatta
     1981 taataggagt ggttgtaatt tggaaggtta tagatgcaac aaaggcagta tttaatgtag
     2041 ataattataa tacattctta tctattcagt gtgattctac tattcgcaat gtttcaagac
     2101 tttatccata tgatgtatct gaagatggag atgaaaaatc tcttcgtggt agtagtcagg
     2161 aaatagcaga tagattaaaa gatgaattac aatcaagggt tgatattgca ggaattgaag
     2221 tgtgtgaagt gagaattact catctttctt atgcaccaga gattgcagca gcaatgttac
     2281 aacgtcaaca agcagaggct ataatagcag cacgtaaaaa gattgttgag ggggctgtaa
     2341 gtatggtaga gatggcattg actaatttaa gtgaaaataa tgttgtgact ttggacgaag
     2401 aacgtaaagc agctatggta agtaatctgt tagttgtgct ttgtggcaat aaagatgcac
     2461 aaccagtggt aaacagcagt tctatttatt aaattataaa aagtttaata gtttatttta
     2521 ttgatatata gaaaatttag tagttcattt tattaaatta tagaaagatt aatggtttgc
     2581 tttattgaat tataaaaagt ttaataattt attctattga tatatagaaa atttagtagt
     2641 tcattttatt aaattatata aagattaatg gttttcactt tattaaatta taaaaagttt
     2701 aatagtttat tacattgata tattgaaaaa ttgaaggaaa taaaaatact tgtcagcaag
     2761 aaataaaaat gatataagaa tgaataagag aattgtaaaa aaataaaatg attataaata
     2821 aaagataaaa atattgtaaa aaagagggtg cctctggtga attaaattca cacagagaca
     2881 cctttttaat taatttttta aattagtata ttattgttta attaatagta tagtactatt
     2941 taattaatct aaatttctaa ggtcttccat aagcttagtt ttgtcagccg ttttttcatc
     3001 tttcattttt ataactttag caggagaacc agcaacaacg gcaccagctt ctacatcagt
     3061 agttacaaca gcaccagctg caacaacagc acctttaccg attctaacac cttcaagaat
     3121 aactgcatta gctcctatta aaacatcatc ttcaactata acaggagtag cagaaggtgg
     3181 ctctaaaaca ccagcaacaa cagcaccagc acctaagtga acatttttac caagagttcc
     3241 tctagctcca ataacagcat tcatatctac catagaacct tcaccaataa cagctcctat
     3301 atttataaca gctcccatca ttacaacagc atttttttct atagtaacca tgtctcttat
     3361 tattgcacct ggctcaattc ttgcatgttc acttaaagta ttttttagag gaatagcaga
     3421 atttcttcta tcatattcta catgagtatc tgttatatca tttccatgtt tatctaatac
     3481 ttccattata tcctcatagt cacctacaaa tatataagaa ccattacttc cgaatacctt
     3541 aaatttatca gttgattgga agtgtaaaga gttagtattt acatatacct taacaggtgt
     3601 tttcttttta acttctttta tataccttgc tatttcataa gcatcgttta aatttaccat
     3661 ttgttaattc tccttgtatt tcattatatt tcttttatta tatacttatt tgtcaatttt
     3721 agtatatact tacttcttat tatttatatt ttattttagt tagtttttat tgtatagaca
     3781 tagtattaaa taaatttatt atatatgttt gatttgtatt gcgtattatt atatctatat
     3841 tgcatatgtt taatttatat tgtgtattat tatatttatg ctattatccc aacatgctgt
     3901 ccatattata aaatcctggt ttttgcttaa ctaagtattt ggcagcagct atagaaccac
     3961 ttgcaaagat accacgagat tgagcttgat ggcttattgt aagaacctca ttgtctccag
     4021 caaatagagc atcatgttcg ccaacaatat ttccacctct tatagcatga ataccaactt
     4081 catttggttg tctttttgca ctacgaccat atctaccata attattttca acgtttggca
     4141 aaacctcttt tatagcgtta gcaatcataa cagctgtgcc acttggggca tctacttttc
     4201 tgttgtgatg tttttctatt atttctatat caaatccttc tagtaattta gctgcatctt
     4261 taaccaattt tactaataca tttacaccaa gagacatatt atatgattgg aatacaggaa
     4321 taactttagc cgcttcacgt attttgttca tttcgtcatc attatatcca gtagtagcaa
     4381 ttactaaagg tgttttagtc tttaaaacgt aagataagat attatctaaa ttagagtgat
     4441 gagaaaaatc tataactaca tcagcttcct caactatagt actcatatct tcataaattt
     4501 taaggtcgcc ttcatagcta tccagacctc tagctgcaac acaaaccaat tctaattcat
     4561 tatcttctct tatagtatcg gctaaaatct tacccatttt tccatcataa ccagttgcta
     4621 taacttttaa cataatttcc tcctatgatt aagggctaac ttttgaccaa acttactttt
     4681 taccatgcat taatctttac tatgcattaa cttttagccc aaagttaact aattctttct
     4741 ttaatacttc taaatttgct gggtccattt ctgctagagg taatcttaaa tctccaacat
     4801 tgaatcccaa taaattcatt gcagtcttaa ctggtatagg atttacttct ataaataaag
     4861 ctgcgattag agcatccata ccaagttgta attttctaga accttcaata tcgccttcaa
     4921 agaatttagc taccaaatcg tgagtttctt gagggcaaac attagcaagt actgatataa
     4981 ctccttgacc tcctaaagat aataaaggaa gtatagtatc atcattacca gagtagatag
     5041 caaagtcatc tggaactaaa ctagctattt ctgcaacctg tcctaggtct ccactagctt
     5101 cttttacagc aactatgtta tcaattttag caagttcaac tataaggcta ggacttatat
     5161 ttacacaagt tcttccaggg acattgtaaa gtataattgg aagtttaaca ctgttagcta
     5221 ttgtttcaaa atgacgctta agtccagctt tattagcttt attgtaataa ggtgttatta
     5281 ttaatagagc atctactcct aatttttcag cttcttgact taagttaact gagtgcatag
     5341 tatcattaga accacttcca gctataacag gaactctttt attaactttt tcaacaacat
     5401 acttaatagt agcaagttgt tcttcatcag tcatagtatt agcttcacca gtagtaccac
     5461 aagatactat agcatcagta ccattagcta tttggtattc aactaattca cctaatttgt
     5521 caaaatcaac tttgttatcc tttgtaaatg gtgtaactag agcaacagca gaacctttaa
     5581 atatcatata aaatcaatcc cctctttttt atttttgtgt tttatattac agttacttct
     5641 aatgcttgtt tttgagttac tattaatatt ttacaaaatt atatatttat acaagtttgt
     5701 atattatact aaatcgtatg ataaagccat ttcagctatt tgaattgcgt tagttgcagc
     5761 accttttctt atattatcag caacaaccca aagatttaca ccattatcaa cactaaaatc
     5821 tcttcttatt cttccaacaa acacttcatc tctatcatca aattctacag cagttggata
     5881 ttcgttttta gcaggattat caactactac aacacctgga gcttcttcaa gtgtttttac
     5941 taaatcatct aactcaaatg gattgttaaa ctcaacattt atagattcac tatgaccatt
     6001 ttttactgga actcttacag tagttgcagt tatttttaaa tcgtagttat caagtatttt
     6061 catagtttca tttaccattt tcatttcttc tttagtgtat ccattttcag tgaatgaatc
     6121 tatatgagga agacagttgt aagagatttg atgagggtag aatccagtag gattaccgtt
     6181 cattcctttc tctaaatctt caacaccttt aacaccagaa ccagatacag cttggtaagt
     6241 agagtaaaca actctcttaa ttttgtattt atcatcaaga gctttaaggg gaaccatagc
     6301 ttgtatagta gagcagttag gattagctat tataccctta tgatttttta tggcttctgg
     6361 attaacctca ggaactacta aaggcacatc tggattcatt ctccattgac tagagttatc
     6421 tactactaag attccatttg aagcagctat tggagcatac ttttcactaa tacttccacc
     6481 agcagagaat aatgctattt gtatgcctct atcagtaaat gaagtttcct ttaattcttc
     6541 tactatatat tctttaccac aaaacattac tttagaacca gctgatttag aagaagagaa
     6601 taaaaataga ttttctattg gaaaatttct ttcttctaat acttttaaaa atgttctacc
     6661 taccattcca gtagcaccaa ctattgctac atttactttt ttcatataaa ttcaccccaa
     6721 ttttaaatta ttaaaacatt attttatttt agttatacaa gtaagatatg ttaatatttt
     6781 tatatatcca aaaactttaa tattatatta acaactttaa ttatatacaa aaaacgtaca
     6841 aaggtatact ttgtacgtct aatttatcac tcaaagtaaa ccctgtagct catcacctac
     6901 aaaaataagt gacagtatta cacatgttat gtgcaatccc agaaaatatt attgcaagaa
     6961 atattttctt cggctgtaaa tcctttttcc aatcattaac acctgccagc tactattgga
     7021 tactcttagt tacagctacc tctaccctag gttaatagga tattaaaatt tgattattct
     7081 aataataata catatttaag aaaaaatcaa cttatttata taaatattgc taaaatttaa
     7141 atccaaaatt tgtcaattct tgttttaaca cattaagatt agtttcttcc atttcagcta
     7201 gaggaagtct taaatcacca acattaaaac ctaaaatgtt catggcagtt ttaacaggaa
     7261 ctggatttac ttctataaat aaagcagcaa ttaaagcatc catatcaagt tgtaattttt
     7321 ttgagccttc aatatcacct tcaaagaatt tagttactaa atcatgtgtt tctttaggac
     7381 atatgttagc aagtacagag ataacaccac ttccacctaa tgataatagt ggtagtatag
     7441 tatcatcatt atcggagtat atagcaaagt ctttaggtac taatttagct atttctgcaa
     7501 cttgagctaa gtctccactt gcttccttca cagcaactat attatctatt ttagcaagtt
     7561 cagccacaac agatggcttt atattcactt tagttcttcc tggtacgttg tataaaataa
     7621 ttggcaactt aacgctattt gctattgttt caaagtgaag tttaagacct ttctcattag
     7681 tcttattata gtaaggagtt attattaaaa gaccatccac ccctaatttt tcagcttctt
     7741 gactcatatg aacagacaac atagtattgt ttgaaccagt acctgctata acaggtattc
     7801 tcttattaac tttttcaact gtatatttta ttacagcaaa aatttcagat tcactcatag
     7861 tagtcgcctc acctgttgtt ccacaaacaa ctagtgcatc tgtgccattc tcaatgtgat
     7921 attcgattaa ttcacctaat ttttcaaagt tgacattatt atcctctgta aatggggtaa
     7981 ctaaagcaac agcagaacct ttaaataaca tataatcaaa tctccttttt tatctaaatt
     8041 taatttttta agtacaataa taattatagt acaaattaat taattttaat aggta
//
LOCUS       DAYAOO010000131         7832 bp    DNA     linear   BCT 12-OCT-2024
DEFINITION  TPA_asm: Clostridioides difficile isolate ST8-SSI-h139-18
            SAMN40601845-rid21577343.denovo.135, whole genome shotgun sequence.
ACCESSION   DAYAOO010000131 DAYAOO010000000
VERSION     DAYAOO010000131.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN40601845
            Sequence Read Archive: SRR28438827
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 7832)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7832)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-MAY-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-MAY-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002157583.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002157583.1
            Genome Coverage       :: 163x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/11/2024 16:19:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 4,038
            CDSs (total)                      :: 3,963
            Genes (coding)                    :: 3,930
            CDSs (with protein)               :: 3,930
            Genes (RNA)                       :: 75
            rRNAs                             :: 6, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 60
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 33
            CDSs (without protein)            :: 33
            Pseudo Genes (ambiguous residues) :: 0 of 33
            Pseudo Genes (frameshifted)       :: 7 of 33
            Pseudo Genes (incomplete)         :: 25 of 33
            Pseudo Genes (internal stop)      :: 11 of 33
            Pseudo Genes (multiple problems)  :: 8 of 33
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7832
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN40601845-rid21577343.denovo.135"
                     /isolate="ST8-SSI-h139-18"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Denmark"
                     /collection_date="2018"
                     /collected_by="Statens Serum Institute"
     gene            191..1594
                     /locus_tag="ACGI5H_003618"
     CDS             191..1594
                     /locus_tag="ACGI5H_003618"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893682.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="APC family permease"
                     /protein_id="HFG9699303.1"
                     /translation="MEKKKIGLWSLVFMNVSALYGIRWIAKSTASSFGLGLGAIPMWL
                     LFSFIYFVPGALICAELASTYQKGDGGLYDWVKEAFGEKYGFLVSWLNWTAKIFWYSS
                     FLTFLAVNVSYTIGNPALADNKMFVLILSLIIFWALSLIATKGISFTKIFTNTGALGS
                     TIPSAILIIFSFVAVFVLKKHDIASTYTIASMTPKLNMDAFVAISAIMFGLAGAETAA
                     NFITEIDKPEKNFPKAILISAGIVASLYVLGSIAITMIIPPDQITASKGVLDALSAVC
                     ASLGIGSWLVQLIAFGIAFSVLGAIVLYIASPIKMLFGSVKKGIFPDSLVEVNEHKIP
                     SKAVILQAIIVTIILLVTTLMPSVDAIYNVLVTMTALTALFPYVLLYASYIKLRKERP
                     DEIRPYTMAKSTSTCLGLAKMVLVVTVVGILLSAAPVMPTFAENVIYEIEMIGGGLLV
                     ILSGLWLWNRYEKKTAK"
     misc_binding    1685..1925
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            1968..2666
                     /locus_tag="ACGI5H_003619"
     CDS             1968..2666
                     /locus_tag="ACGI5H_003619"
                     /EC_number="3.2.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890826.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008782 - adenosylhomocysteine
                     nucleosidase activity [Evidence IEA];
                     GO_function: GO:0008930 - methylthioadenosine nucleosidase
                     activity [Evidence IEA];
                     GO_process: GO:0009116 - nucleoside metabolic process
                     [Evidence IEA];
                     GO_process: GO:0009164 - nucleoside catabolic process
                     [Evidence IEA];
                     GO_process: GO:0019509 - L-methionine salvage from
                     methylthioadenosine [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="5'-methylthioadenosine/adenosylhomocysteine
                     nucleosidase"
                     /protein_id="HFG9699304.1"
                     /translation="MNVIGIIGAMDEEVSILVDLMDIRETIKKASLEFYKGILEGKNV
                     VLVKCGIGKVNSALCAQILISEFKVDAIVNTGVAGALNEKLDVNDIVISTDAIQYDVD
                     TTAFGDPKGVIPRMKTSVFKADERLIDAAYKSSVEEVKTHKVLKGRVVTGDKFINSKE
                     LKEELVNDFGGYCGEMEGGAIAHVCYLNNTPFVIIRAMSDKADGSADVTYDVFVHDAA
                     NNSKDIVLNMLKSI"
     gene            2689..3690
                     /gene="trpS"
                     /locus_tag="ACGI5H_003620"
     CDS             2689..3690
                     /gene="trpS"
                     /locus_tag="ACGI5H_003620"
                     /EC_number="6.1.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729405.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0004830 - tryptophan-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006436 - tryptophanyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tryptophan--tRNA ligase"
                     /protein_id="HFG9699305.1"
                     /translation="MSEKKVIFSGAQPSGKMTLGNYLGAIKNWTELQDNYDCYYSIVD
                     LHAITVPQDPKVLRANTIELLAQYIACGLDPEKNTIFIQSHVKEHVELMWVLNTMTYM
                     GELSRMTQFKDKSQKSEANLNAGLFTYPVLMAADILLYQTDLVPVGDDQKQHLELARD
                     LANRFNNRFSPTFVVPEGYYPKGGARVMSLQEPTKKMSKSDSNENAFILLADDSDSIK
                     RKIKRSVTDSLGVVKYNDEQPGIKNLIDIYSNLSKKSVEEIVNMYEGKGYGIFKEDVA
                     EVVSEALRPIREKYVDLLNNKDYLEKIYSMGAEKAEKQARKTLRKVYKKVGFIERRY"
     gene            complement(4342..5909)
                     /locus_tag="ACGI5H_003621"
                     /pseudo
     CDS             complement(4342..5909)
                     /locus_tag="ACGI5H_003621"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_021426623.1"
                     /note="frameshifted; internal stop; incomplete; partial in
                     the middle of a contig; missing N-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="iota toxin protein Ib"
     gene            complement(5902..6427)
                     /locus_tag="ACGI5H_003622"
                     /pseudo
     CDS             complement(5902..6427)
                     /locus_tag="ACGI5H_003622"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890822.1"
                     /note="frameshifted; internal stop; incomplete; partial in
                     the middle of a contig; missing C-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="iota toxin protein Ia"
     gene            complement(6816..7562)
                     /gene="cdtR"
                     /locus_tag="ACGI5H_003623"
     CDS             complement(6816..7562)
                     /gene="cdtR"
                     /locus_tag="ACGI5H_003623"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454924.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LytTR family response regulator CdtR"
                     /protein_id="HFG9699306.1"
                     /translation="MDILIFDNDVCFGMKLKEKINNILIKEGFDNDVVRLYHNANLLL
                     KELTEKNKVRIYFIVVDAKYKISNELCDGLWIAQKIRESDYISPIIFLTNHIEMILGI
                     FDYRLEVMDFILKHDMEIAESKIKACIKIAHKRYIKEKNYRSNFFTIYSDFSLWKISF
                     DEVIYFETSTIPHKIKLVTTSRIFEFYKSLKSLPDLDACFIRVHKSFVVNKYHIVSLD
                     LKKNNIKMSNGHICRISNTYRNILKNIIKT"
BASE COUNT         2808 a          922 c         1132 g         2970 t
ORIGIN      
        1 taaagtggta aaacttttaa atttatcatt tttaataaga tttgatttca aagtatttaa
       61 ggtttattat taaaactgtt tttgaatatg caaatatttt gaaaaatatc agtttaataa
      121 taatgaatct attttattaa ttttgaaatt aaatttaaaa taattaatag agaggggaaa
      181 ttaaattagg atggaaaaga aaaaaatagg cctatggagt ttggtattta tgaatgtatc
      241 agctttatat ggtataagat ggatagctaa atctacagca tcaagctttg gtttaggatt
      301 aggtgcaata cctatgtggt tattattctc atttatatac tttgtaccag gagctttaat
      361 ttgtgctgaa ttagcttcta catatcaaaa aggtgatgga ggtctttacg attgggttaa
      421 ggaagccttt ggagaaaagt atggattttt agtttcttgg ttaaactgga cagctaaaat
      481 attttggtat tcttcatttt taactttctt agcagtaaat gtttcttata caataggaaa
      541 tccagccctt gctgataata agatgtttgt acttatatta tctttaataa tattctgggc
      601 attatctctt atagcaacta aaggaataag ttttacaaaa atatttacta atacaggtgc
      661 attaggttca acaataccaa gtgctatact tataatattt tcatttgtag cagtatttgt
      721 gttgaaaaaa catgatatag cttctacata cacaatagct tcaatgactc caaaacttaa
      781 tatggatgca tttgttgcta tatcagctat aatgtttggt ttagcaggag cagagactgc
      841 tgctaacttc ataacagaaa tagataagcc tgaaaagaac ttccctaagg caatattaat
      901 atcagctgga atagtagctt cattatatgt attaggttca attgcaataa caatgataat
      961 accaccagac caaattactg cttctaaagg tgtattagat gcactttctg ctgtttgtgc
     1021 gtctttagga attggttctt ggttggttca attaatagct tttggtatag ctttttcagt
     1081 attaggagca atagttcttt acatagcatc accaataaaa atgttatttg gtagtgttaa
     1141 aaaaggaata tttccagata gtttagtaga ggtaaatgaa cacaagatac cttctaaagc
     1201 agttatactt caagcaataa tagttactat aatactattg gtgactacat taatgccttc
     1261 tgttgatgct atatacaatg ttcttgtaac tatgacagca ttaactgcat tattcccata
     1321 tgtattgtta tatgcttctt atattaaact aagaaaagag agaccagatg aaattagacc
     1381 ttatactatg gcaaaatcaa caagtacttg cctaggttta gcaaaaatgg ttttagttgt
     1441 aactgtagtg ggtatattat tatctgcagc accagttatg cctacatttg ctgaaaatgt
     1501 tatatatgag atagagatga ttggtggagg tcttctagtt atattatctg gtctatggtt
     1561 atggaataga tatgaaaaga aaacagctaa ataaaatgta ttttaaaaat ttcttttgga
     1621 tattataata tatagttgac aatttatagt gtaaggaata ttataaaata aagaaattaa
     1681 taaattaaat cctgagataa gaaatagtaa ataaatatat ttttgcacag agaattaagg
     1741 atgctgagaa cttaataaaa agtatttatt gaatgggtct ttgaggagta aaatgaaatg
     1801 taatttaata ttacagagta tttgatatcg tgtatgcacg ttatagcata tattaagata
     1861 tatatattca attttgagtg tatataaatt taggtggtac cacggaaaat atatccgtcc
     1921 tattgattta ggacggattt tttaatatag aaaatttagg aggaaaaatg aacgtaatag
     1981 gaattatagg tgcaatggat gaagaagtta gtattttagt tgatttaatg gatattagag
     2041 agactataaa aaaagctagc ttagaatttt ataagggaat tttggaaggt aagaatgtag
     2101 tgttagtaaa gtgtggcata ggtaaggtta actctgctct ttgtgcccag atactaataa
     2161 gcgaatttaa ggttgatgct attgttaata caggtgttgc aggagcttta aacgaaaaac
     2221 ttgatgttaa tgatatagta atatcaactg atgctataca gtatgatgta gacactacag
     2281 catttggaga ccctaaggga gttataccaa gaatgaagac ttctgtattt aaagcagatg
     2341 aaagacttat agatgctgct tacaaatctt ctgtggaaga agtaaagact cataaagtat
     2401 taaaaggaag agtagttaca ggagataaat ttataaattc taaagaatta aaagaagaat
     2461 tagtaaatga ttttggtgga tattgtggag aaatggaagg tggagctata gctcatgtat
     2521 gctatttaaa taatactcca tttgtaataa taagagcaat gtctgataag gcagatggaa
     2581 gtgctgatgt tacttatgat gtatttgtac atgatgctgc caataactct aaagacatag
     2641 ttttaaatat gttaaaatca atataaatat ataaggaggt acaaaaaaat gagtgaaaaa
     2701 aaagttatat ttagtggtgc acagccatca ggcaaaatga ctttaggaaa ttatttagga
     2761 gctataaaaa actggactga acttcaagac aattatgatt gttattatag tatagttgat
     2821 ttgcatgcaa taacagtacc tcaagaccct aaagttttaa gagccaatac tatagaatta
     2881 cttgctcaat atatagcttg tggattagac ccagaaaaaa atactatatt tatacaatca
     2941 catgtcaaag agcatgttga acttatgtgg gtattgaata ctatgactta tatgggtgaa
     3001 ttaagtagaa tgactcaatt caaagataaa tcacaaaaga gtgaagcaaa tctaaatgca
     3061 ggtttattca catatccagt tcttatggct gctgacatat tgttgtatca aactgaccta
     3121 gttccagttg gagatgacca aaaacaacat ttagaattag ctcgtgattt agcaaataga
     3181 tttaataata gattttcacc tacttttgta gttccagaag gatactaccc aaaaggtgga
     3241 gcaagagtga tgagtttgca agagccaact aaaaaaatga gtaaatccga ttcaaatgaa
     3301 aatgcattta tactattagc agatgattca gattctataa agagaaagat aaaaagaagt
     3361 gttactgatt ctttaggtgt tgtaaaatac aatgatgaac aaccaggtat taaaaatcta
     3421 attgatatat attctaattt aagtaaaaag agtgtagaag agattgtaaa catgtatgaa
     3481 ggaaagggtt atggcatatt taaagaagat gtggctgaag tagtatcaga agctttaaga
     3541 cctataagag aaaaatatgt tgaccttctt aataataaag attatttaga aaaaatatat
     3601 agtatgggag cagaaaaagc cgaaaaacaa gctagaaaaa ctcttagaaa agtttataaa
     3661 aaagttggat ttatagagag aagatactaa ttattagcta tctttacttg ataaataaat
     3721 tttaaagtta ttaaaaaggt atatgatatg aaagagagag tctcaaagtg aacttttgtt
     3781 catgaggcac tcttttttgt atgaaataaa atatatttta atcatttcaa caatgaaaaa
     3841 gaggattatc tctattttga gacagcatct tttgataata aaaaaagatg agcttttgct
     3901 catctcaaag gggttagatt attcttactt tggggaaagt agaataaagg taaaagttaa
     3961 ctgatgtcaa ctttgtcttt tttgcatatc actactgagc ataaaaaaat cagaaaacca
     4021 tagccttctg aaacaacttc taacatacat tgtattttat acccaatatg taatttatga
     4081 gttaatttta actcttataa tgaaaattgt caataatata tcaaaaaaat attttttaaa
     4141 tttatataat taaatgaatt tatgtttata tataggtgat atgatacaga taattatctt
     4201 tttaatacaa tatagttcta aaaaagaata tattagaaga agataatatt taaataaaaa
     4261 ataccttata aagttaattt tttaatactt tataaggtaa atacatattg tattgtgggg
     4321 ataaatttaa atcatttgat actaatcaac actaagaacc aataactctc tatcatcttg
     4381 agtaattgta tatattctta atttcttgta tgtcataata ttttctccac ctgtaaaata
     4441 actcctaaga ttaacacaat cagttttagg ttgatttgta tctcctaaat aattacgcaa
     4501 ttctttatct ttagtttcaa tatctttaaa tccaaaatat tgtaaagtag cttcaactct
     4561 atatttttgg acataatcga gagcttcttt attagtttat gttggtgtaa aatacatacc
     4621 atttatataa gcctttattg tacttggatt aaatttaaaa tctgcagaat atattttatg
     4681 tgtaactatt atttcttgaa cagttggaat tttaacttct ggttcatcaa gtatttcagg
     4741 agtactattt agctctgtaa tagataagtt atctaagtat attgtatcac tatcaattaa
     4801 tgctatattt atattagaag aatctttttc agtagtttca aattcataac taaattttgt
     4861 atatccttgt tctagtacca aataatccgt tttttcttct tttactttta tatttacaat
     4921 tattgaatta tatgttaaag gattttttga attttactaa aaacataacg tttataaggt
     4981 tttagttcag acataggtat tttaatcttc gtctcaccat ttaatctatt tgctgagcct
     5041 tttaaaccat cttgatttgt agtattaaca ttactccata tactagggta attattgtaa
     5101 tcatcaaaat tagtaaagta agttggtgtt tttataagta tattcattcc tctttcaagt
     5161 ttaacattac atatttgttt atcagacaaa gtttttaaac tgtctttaat cttattgcct
     5221 atattatcat caaatatgag ttcaacacaa ctttcatcta ttggtatatt attaaaatat
     5281 aacaaaccat cttttttagt agtgccaaaa gttttttcaa ttgcttctcc aattgtaagt
     5341 tcaggtgttt tatcttctgg gacctgtaaa cttttagcag taattcttct tttgtaagat
     5401 tcattttctg tatctaatat aatagataca gaaatactgt caatttgacc tatatcgtct
     5461 taccaactat ttcattctgt tactatttgt ccagaaccat tttttgtacc aaaatttcca
     5521 cttacttgtg ttgtttctaa tttaatttgc tttccatcat ctaatttttt taattaatta
     5581 taatttatag gaatcagtct agaactaaat tgatacattg tgttaagagc cataggtgaa
     5641 aatccttttt tgagataagt atttccagga gatagattat tgccaatttg attttcttgt
     5701 gctttgatag ttgataatgc atctccatct aacactaaat ttgttgttgg tgtcactttg
     5761 tacataggtg cagtacctgt gttgtagtat ctaatatttg catttatata tgcagattct
     5821 cctttgttta tacttaatcc agtatttcat gattatccat tgctattttg aacagcagtt
     5881 gaattatctg ttgtatggta ataatttgtc ttgtatagtt tctttaaact cattaaattt
     5941 ttctaatgaa atttcgtttt gattttttgt tcttattact ttattaaatg caaatttttc
     6001 tggagattca aaataatata catacatagg tttatctatt ttattttttg atatagcatt
     6061 tcgaagttct ctatattctt tttctcaaga atttgcttct atttgataat cataaaaata
     6121 atttcttgtc tgagaatatt tgcttatctc tatagaatct tttttatatg atcctaatac
     6181 ttctttttca gatttttcaa gtttttgatc ttttctttct cattctttag ccttttcttt
     6241 atctttaaaa aaatccttct gatctttcta taggagcctt gtaagtagta ttacaaactt
     6301 ttccactata gctttgtaaa tcttgtgcat aaatgttatt aggtaacaaa ctacctaaag
     6361 ttagatataa tatcaacaat atagatatac aattactaat acttttatgt ttcctaaatt
     6421 ttttcattta ttctccctac aaatattagt ttagttaact tttgaatttt aatttattta
     6481 gattatataa tctaaataag aattttttat ataaatttca taaaatatgt aggtatatat
     6541 cataaaaata tgtatttata tgatatgtca gtacaaaata acaactgaat attttaaaga
     6601 gactatttcg tacttttatg atttaatgag ctatcttatc gaatcataat ctaggaacaa
     6661 ttgttataat atctaatagt agttatatat gatatagtca gtatgtgttt tttcacaata
     6721 tgattattat atagaggatt cttagggatt actctttttg tataaaaaag agatggttca
     6781 aatttttatc ttgagacatc tcctttttct atttattatg ttttaataat attctttaaa
     6841 atatttctat atgtattaga tatacgacat atatggccat tactcatttt aatattattt
     6901 ttctttaggt cgagagaaac aatatgatat ttattaacta caaaagattt atgtacacgg
     6961 ataaagcatg catctaaatc tggtaaagac tttaaacttt tatagaattc aaatattcta
     7021 gaagtagtca ctaattttat tttatgtgga atagtgcttg tttcaaaata tataacttca
     7081 tcaaatgaaa ttttccatag tgagaaatct gaatagatag taaaaaaatt agagcgataa
     7141 tttttttctt taatgtatct tttgtgagca attttaatac aagcttttat tttactttca
     7201 gcaatttcca tatcatgttt tagtataaag tccataactt ctaacctata atcgaagatc
     7261 cctaaaatca tttctatatg atttgtaaga aatatgattg gactaatata atctgattct
     7321 ctaatttttt gtgctatcca taatccatca cataattcat tacttatctt atattttgcg
     7381 tctacaacta taaaatatat tcttacttta tttttttcag taagctcttt taataacaaa
     7441 tttgcattat gatataatct tacaacatca ttatcaaaac cttcttttat taaaatatta
     7501 tttatttttt cttttagttt cattccaaaa caaacatcat tatcaaagat taatatatcc
     7561 actaaatacc ctcctataaa aaattcaaaa gtaaaaaaac aaaagtattt tatagaaaat
     7621 acataaaata acactaggag ataaataaga ttaaggatag ttagaattaa ggtatattta
     7681 tgcttgttta tatagtatat cttatactta tagtttacaa taataaagta aattaaatca
     7741 atatattatt ataaaaaatt tatttatatt aaataatatg ttttatatta acttagataa
     7801 taaaaatttt ctggaatttt tattcttata cg
//
LOCUS       DAYAOO010000132         7813 bp    DNA     linear   BCT 12-OCT-2024
DEFINITION  TPA_asm: Clostridioides difficile isolate ST8-SSI-h139-18
            SAMN40601845-rid21577343.denovo.136, whole genome shotgun sequence.
ACCESSION   DAYAOO010000132 DAYAOO010000000
VERSION     DAYAOO010000132.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN40601845
            Sequence Read Archive: SRR28438827
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 7813)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7813)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-MAY-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-MAY-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002157583.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002157583.1
            Genome Coverage       :: 163x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/11/2024 16:19:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 4,038
            CDSs (total)                      :: 3,963
            Genes (coding)                    :: 3,930
            CDSs (with protein)               :: 3,930
            Genes (RNA)                       :: 75
            rRNAs                             :: 6, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 60
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 33
            CDSs (without protein)            :: 33
            Pseudo Genes (ambiguous residues) :: 0 of 33
            Pseudo Genes (frameshifted)       :: 7 of 33
            Pseudo Genes (incomplete)         :: 25 of 33
            Pseudo Genes (internal stop)      :: 11 of 33
            Pseudo Genes (multiple problems)  :: 8 of 33
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7813
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN40601845-rid21577343.denovo.136"
                     /isolate="ST8-SSI-h139-18"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Denmark"
                     /collection_date="2018"
                     /collected_by="Statens Serum Institute"
     gene            934..2292
                     /locus_tag="ACGI5H_003624"
     CDS             934..2292
                     /locus_tag="ACGI5H_003624"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424358.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="solute carrier family 23 protein"
                     /protein_id="HFG9699307.1"
                     /translation="MKAKSTSKFELDGIPPLKEAIPLGLQHLMAMVIGSCLPAILIAN
                     AAGLNHKMSTLLIQAALVFAGLSTLLQLYPIPLFKGFKLGGGIPVIMGATAMFIGAGV
                     SVASKYGLPVLFGSQIIAGIVIIIIGFGLKKIRFIFTPAVSGTIVACMGLGLFPIAIK
                     NLAGGMGNETFGNPINFIVGISVSLMILGLNKYGKGLFKDASILVSIIFGYILSLILG
                     IVNFSSIQEFTLVALPKPLAFGLDIRLEVVVMFSIIYLVEIADIMGACTLSAVGGLNR
                     QVTDEELSSAVLGNGVLSTIGALFSATPMGMFGQNSAIVSNTKVVSKFVLAIGGIGLF
                     LAGISPLLANLIRTIPPCVVGGATLVIFSTLTTSGLRLVSMDGFNQENSMILGLSMAS
                     GIGFMVAPQVLEKFPKFIETLLADSSVVSGAMVAIIIQALYMVKFPGNKSDKVEDKNK
                     SL"
     gene            2399..3193
                     /locus_tag="ACGI5H_003625"
     CDS             2399..3193
                     /locus_tag="ACGI5H_003625"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893424.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="FAD binding domain-containing protein"
                     /protein_id="HFG9699308.1"
                     /translation="MVTIKEYSVPQSLEEAYKILISKKNNVILGGCGFIKLSNKNIGT
                     AIDLKDINLNYIKEDKKNILIGADTSLRSLEIDKTIKNYCSGILSSAVSNIVGVQFRQ
                     GARIGASVFSKYGFSDLIPALLVVGAKVRLYNKGILELSEFLDSELSRDILVEVILPK
                     KDAIAVFDSIRKCTGDFSVLNSAMLKENDTYKIAIGARPQKARLALEASNILNKEKDI
                     DKASIVASKELTYGSNMRASKEYRKDMASALVKRMYNAIEEGMYND"
     gene            3186..5492
                     /locus_tag="ACGI5H_003626"
     CDS             3186..5492
                     /locus_tag="ACGI5H_003626"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890192.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="molybdopterin cofactor-binding domain-containing
                     protein"
                     /protein_id="HFG9699309.1"
                     /translation="MINKGIRKIDSTAIVTGKPLYTEDLIMHKDVLTLKLLRSPHAHA
                     KIKNIDTSKAEKIPGVVGIYTYKDVPQVRYCVPGQTEPEASPYDRVLLEDTVRFIGDE
                     VALVAAEDEKTALKALKMIKVDYEVLKPVFDAREAEGNEVVIHPEKDIVEPYPFGLDA
                     KNNIVSKEFFEFGDVEAKLKESDFVVESSYKTQSQSHCMMETHRSYSYKDINDRIVVV
                     SSLQSPHNVKRILRKVLGIPSSKIRVIKPRIGGGFGGKNIAATDIFTAFVTMKTGRPA
                     KFVFTRSETFVGSNSRHEMFFDVKVGADKEGNLKAIELKSLNNTGAYGGNGVSVSSES
                     GHNTLPIYNDIDAVRFNARTVYTNRLPAGALRGYGATQGIFAIDSAIDELAHKIGMDP
                     LEFRIKNIIDRYTNGKAAEDEILSCELRQCIEKGKKLINWDDKYPCKDIGNNKVRAVG
                     MAVANHGSGIPRVDMATVTIRMDEDGTYKILSGLADLGQGADTIQAQIAAEALNTTVD
                     RISIYTGDSDLCPYDTGAFASCTTTVTGNATIKTANKLKDILLSVAESKLGFKKEDLE
                     LGKDRVFVKNDNSKFVLLEELGRESVGGIGFASDDVPVVLEATESFGMLKKIKPFIAG
                     FAEIELDKNTGEYKVINFACVPDCGTVINPTLARIQVEGGVMMGIGFAMYEDPIFDKD
                     GRLLTDSFLQYKVPTKKEVGNILVDFAENFDPGGPYGAKSLGEIVIHTPAPAIANAIF
                     NATGVRLRELPMTFEKVYMGMKNNNKQL"
     gene            5631..6908
                     /locus_tag="ACGI5H_003627"
     CDS             5631..6908
                     /locus_tag="ACGI5H_003627"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905725.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-guided endonuclease InsQ/TnpB family
                     protein"
                     /protein_id="HFG9699310.1"
                     /translation="MSNRIKNIHYGTQRQQLKNLTKKEYQALREMCFLAKNLYNVGTY
                     NVRQHYFNQGEHLNYEANYHVCKENENYKLLNSNIAQQILKEVDSSFRSFFGLIKLAK
                     EGKYDFRGIKSPKYLDKEGFFSIIIGQIRIKEDGILNVPMSPAFKKLYGKVSIKVPQN
                     ILEKKIKEIRIIPKHKARFFEIQYCYEIPKSEEVSNQKNALAIDLGLENLCTCVTNLG
                     DSFIIDGKRLKSVNQWANKQNDKIEALKLKKNITAITRKQFKVWNKRNNQVKDYVNKT
                     CFYIIDYCVKNNIGNLIVGYNAKLEKSDNMERKIYRNFIRIPFGEIKGKLEYLCKIKN
                     INFIRQEESYTSKSDFFADDFLPDINVDNVKKYDFKGERITRGQYKSSVGIIINADVN
                     ASFNILKKSQVVNLSNLQNNPQILKQPQRVRIS"
     gene            7091..7813
                     /gene="yqeC"
                     /locus_tag="ACGI5H_003628"
     CDS             7091..7813
                     /gene="yqeC"
                     /locus_tag="ACGI5H_003628"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435113.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="selenium cofactor biosynthesis protein YqeC"
                     /protein_id="HFG9699311.1"
                     /translation="MELSNIIEKNEIITVVGAGGKTSFINYFANFYRNKLKVLLTTTT
                     KIYVPNDYDNIIITIDGTVIPSICHGITVCGSYINNENKLVSIDSSILDEIVDQFDLV
                     LIEGDGSKRKKLKGWNAKEPVVYHRTTKTIGILDITSFGMNINEENIHRVEIFKKIAN
                     LDTSSINSSSTVSIENLKNIVLNPNGLFKNYSGKRVLFINKVENEKYKNLAIKLIENI
                     KEYESEIEIFYGSVKQKFCVRY"
BASE COUNT         3082 a          840 c         1456 g         2435 t
ORIGIN      
        1 agatacaaat atagtaaagg agagtacatt ggtacaactg agatacatag cttattaagt
       61 ttttctgtct tatgagaatt atattataaa atattcataa atattttgag tttaaattaa
      121 ataattattt tatgcttaga ttaattgata tttaattaat ttaataacaa aaacagtgaa
      181 agagtaaata atattattta cagggggtaa agcaaagtat gttaaataaa ttgtactttt
      241 ggccccgtac atagagaaat ctatgtagga cacaacttta aaaccagtaa atcctaaagc
      301 cttgcaacta caataaaaga tagaaagaaa cttttatgaa tgtggtgaaa accagaaaca
      361 atagtgagga tggtatatgg tgagagccta agtacttaaa aatggacatt tggtcgccaa
      421 gcctagaaat aggaaggtca aacgactatc tcgagagaga gtacactata agcgattgat
      481 agtggaaacg ggttgctctt agcaggtaat gctgaagatg aagaaatagt ctacgctcat
      541 atgaaagtat gaggtcactg gatttgaagt gacatctata aagtagcgtt tataggtaaa
      601 tgtttaaaac ttgaaacatg taaatactta tgaaaactta taacttataa tgattaagat
      661 tgaaagattt aaattgaatt aaatttacta taaaaaatta aaaattcata gctataatac
      721 tcttatattt gtaaagcatg gtatataatg tatacaaaat taaagaatac gtgtatttgt
      781 taataattaa atttattgca tctgtttttt aagactaaaa acttaaatat atgttggagt
      841 atagttgata tttatgaaca tcattaattt aatatattag atttttaagt atttatataa
      901 ttcaataagt tttatgtaac gggagttttt attatgaaag caaaaagtac atcaaaattt
      961 gaattagacg gaataccacc actaaaggaa gcaatacctt tagggttaca acacttaatg
     1021 gcaatggtaa taggtagttg tttaccagcg atattgattg caaatgcagc tggacttaat
     1081 cataagatgt caacattatt gattcaagcc gcattagttt ttgcaggatt atcaacttta
     1141 ttacaattat atccaatacc tttgtttaaa ggttttaaat taggaggagg aataccagtt
     1201 ataatgggag ctacagctat gtttatagga gctggggtat ctgttgcaag taagtatgga
     1261 ctaccagtat tatttggctc tcaaataata gctggtatag taataattat aattggtttt
     1321 ggtcttaaaa aaatacgatt tatatttact ccagctgtat caggaacaat agttgcatgt
     1381 atgggtcttg gactttttcc aatagctata aaaaacttag ctgggggtat gggcaatgag
     1441 acttttggga atccaattaa ttttatagtt ggaatatctg tatctcttat gatattagga
     1501 ttaaataagt atggaaaagg attatttaaa gatgcatcaa tattagttag cataattttt
     1561 ggatacattt tatcattaat tttgggtata gtaaattttt cttcaattca ggagtttact
     1621 ttggttgcac ttccaaaacc acttgctttt gggctagata taagacttga agttgttgta
     1681 atgttttcaa taatatattt agttgagata gctgatataa tgggtgcttg tacactttct
     1741 gcggtaggag ggcttaatag acaagtaaca gatgaagaac tttcttctgc tgttttagga
     1801 aatggagtac tctctacaat aggtgcatta ttttctgcaa ctccaatggg gatgtttgga
     1861 caaaattctg caatcgtttc caatacaaag gttgtaagta aatttgtact agctattgga
     1921 ggaattggat tatttttggc aggaatatcg cctttattag ctaatttaat aagaacaatt
     1981 cctccctgtg tggttggagg agcaacactc gttatatttt caactcttac aacatctggt
     2041 ttaagacttg ttagtatgga tggatttaat caagaaaata gcatgatatt aggtctttct
     2101 atggcttctg gtattggatt catggtagct cctcaagttc ttgaaaaatt tccaaaattt
     2161 atagagacat tacttgcaga ttcaagtgta gtttcaggag caatggtagc cataataatt
     2221 caagctttat atatggtaaa atttcctgga aataaaagtg ataaggttga ggataaaaat
     2281 aaaagtttat aatgtaaagg tttaatatat gtgaattaaa tatactacaa ttataaatat
     2341 aaataaaaga tttattaaaa acttttgtgt tttaataagt taatgatggg gggataagat
     2401 ggttactata aaggaatatt cagttccaca gagtttagaa gaagcatata aaattttaat
     2461 ttctaaaaaa aataatgtta ttttaggtgg atgtggattt ataaaattaa gtaataaaaa
     2521 tataggaaca gcgatagatt taaaagatat aaatctaaat tatataaaag aggataaaaa
     2581 aaatattttg ataggtgcag atacttcact tagaagttta gaaattgata aaactataaa
     2641 aaattactgt agtggaatac tttcaagcgc tgtttctaat atagttggtg ttcaatttag
     2701 acaaggggct agaattggtg caagtgtatt ttcaaagtat ggcttttctg acttaatacc
     2761 agcacttttg gttgttggag cgaaggtgag attatacaat aaaggaatac tagagttaag
     2821 tgagtttttg gatagtgaat taagtaggga tatattggtc gaagtaatac taccaaaaaa
     2881 agatgcaata gctgtttttg actcaataag aaaatgcaca ggagattttt ctgtattaaa
     2941 ttcagcaatg ctaaaagaaa atgatactta caaaatagca attggggcaa gacctcaaaa
     3001 agctagatta gcacttgaag cgagtaatat attaaataaa gaaaaagata tagataaggc
     3061 atctattgtt gctagtaagg aacttactta tggaagtaat atgagagcta gtaaagagta
     3121 cagaaaggat atggcaagtg cattagttaa aaggatgtat aatgctattg aggagggaat
     3181 gtataatgat taataagggg ataagaaaga tagatagtac agcaattgtc acaggaaaac
     3241 ctctatatac tgaagacctc attatgcata aagatgtttt gacattaaaa ctacttagaa
     3301 gtccacatgc tcatgctaag ataaagaata tagatacatc aaaagccgaa aaaattccag
     3361 gggttgtggg tatttatacg tataaagatg taccacaggt cagatattgt gttccaggtc
     3421 aaacagaacc agaagcatca ccttatgata gagttttact tgaagataca gttagattta
     3481 ttggagatga agtagcttta gtggctgctg aagatgagaa aacagcactt aaagccttaa
     3541 aaatgataaa ggtagattat gaggttttaa agcctgtgtt tgatgcaaga gaagcagaag
     3601 gaaatgaagt tgttatacat ccagaaaaag acatagtaga gccataccct tttggattgg
     3661 atgcaaaaaa taatatagta tcaaaagaat tttttgaatt tggagatgtt gaagctaagc
     3721 ttaaagaaag tgattttgtg gttgaatctt catacaaaac ccaaagtcaa tcgcattgca
     3781 tgatggaaac tcataggtca tattcatata aagatataaa tgatagaatt gttgtagttt
     3841 catcattaca atcaccacac aatgtaaaga gaatacttag aaaagtattg ggtataccgt
     3901 cttcaaaaat aagagtaatt aaacctagaa taggtggtgg atttggagga aagaatatag
     3961 cagcaacaga tatatttact gcatttgtta ctatgaaaac tggtagacca gcaaaatttg
     4021 tatttacaag aagtgaaact tttgtaggtt ctaatagtag acatgaaatg ttttttgatg
     4081 ttaaagttgg tgcagataaa gaaggaaatt taaaagcaat agagctaaag tcattaaaca
     4141 atacaggtgc ttatggtggg aatggtgtct ctgtttcttc cgaatctgga cacaatacct
     4201 taccaatata taatgatatt gatgctgtta gatttaatgc tagaacagta tatactaata
     4261 ggttaccagc aggagcactt agagggtatg gtgctacaca gggaatattt gcaatagata
     4321 gtgctattga tgaattggca cataagattg gaatggaccc acttgaattt agaattaaaa
     4381 atataataga taggtatacc aatggaaaag cagctgaaga cgaaatatta agttgtgagc
     4441 tgagacaatg tatagaaaag ggaaagaaat taattaattg ggatgataaa tatccatgta
     4501 aagatatagg aaacaacaaa gtaagagcag taggtatggc agtagcaaat catggttctg
     4561 gtataccgcg tgtagatatg gcaacagtca ctataagaat ggatgaagat ggcacatata
     4621 aaatattatc tggtcttgct gacttaggtc aaggggctga tacaattcaa gctcaaattg
     4681 ctgcggaagc tttaaatact actgtagata gaatttctat ttatacaggt gattcagact
     4741 tatgtcccta tgatacagga gcatttgctt cttgtacgac aacggttaca ggaaatgcaa
     4801 caataaagac agcaaataaa ttaaaagata tattactttc agttgcagag tcaaagctag
     4861 gatttaaaaa agaagattta gagttgggaa aagacagggt ttttgttaaa aacgataata
     4921 gcaagtttgt tctattagag gaattgggta gagaatctgt tggaggaata ggatttgcta
     4981 gtgatgatgt accagtagtt ttggaagcaa cagaatcttt tggcatgttg aaaaaaataa
     5041 aaccatttat agcaggattt gcagagatag aattagataa aaatacaggt gaatataaag
     5101 tcataaattt tgcatgtgta cctgattgtg gaacagttat aaatccaact ttagctagaa
     5161 tacaagtaga aggtggtgtg atgatgggta tagggtttgc aatgtatgaa gaccctatat
     5221 ttgataaaga tggtagatta ttaacagata gtttcctaca gtataaagtt cctacaaaaa
     5281 aagaagttgg aaatatattg gtagattttg ctgagaattt cgacccagga ggtccttatg
     5341 gtgctaaatc attaggagaa atagttatac atacaccagc accagctata gcaaatgcaa
     5401 tatttaatgc tacaggagtt cgtttaagag agcttcctat gacttttgaa aaagtttata
     5461 tgggtatgaa aaataataat aaacaattat aataaataat aagatgcata aaagcaagta
     5521 aatttaaatt attttgtaaa ataaagtaat taaatggaca ttatatatgg tgttttgtaa
     5581 aaataccgta tataatgtct agtagagtat attctaaagg aggtgagttc atgtcaaaca
     5641 gaataaaaaa tatacactat ggaactcaga gacaacaatt aaaaaactta actaaaaaag
     5701 aatatcaagc tctacgagag atgtgcttct tagctaagaa cttatataat gttggtacat
     5761 ataatgtaag acagcattat ttcaatcaag gagaacatct taactatgaa gctaattatc
     5821 atgtatgcaa agaaaatgag aactataagc ttctcaatag taatatagcg caacaaatat
     5881 taaaagaagt agacagttcg tttaggtcat tttttggatt aattaaatta gccaaagaag
     5941 gaaaatatga ctttagaggg ataaaatcac ctaaatattt agataaagaa ggatttttta
     6001 gcataataat aggtcaaata agaatcaaag aagatgggat tttaaatgta cctatgtctc
     6061 cagcatttaa aaaactatat gggaaagtaa gtataaaagt tccacaaaat atactagaga
     6121 aaaaaattaa agaaataaga ataataccta aacataaagc taggttcttt gaaattcagt
     6181 attgttatga aataccaaaa tcagaggaag tttcaaatca aaaaaatgca ctagctatag
     6241 acttgggttt agaaaattta tgtacatgtg ttaccaattt aggtgatagt tttatcatag
     6301 atggaaaaag gctaaaatct gtgaatcagt gggcaaacaa acagaatgat aaaatagaag
     6361 ccttaaaatt aaaaaagaat ataactgcaa taacaagaaa acaatttaaa gtttggaata
     6421 agagaaataa tcaagttaaa gactatgtaa ataaaacctg tttttatata attgattatt
     6481 gtgtaaaaaa taatattgga aatttaattg taggatataa tgctaagtta gaaaaaagtg
     6541 ataatatgga gagaaaaata tatagaaatt ttataagaat cccatttgga gagataaaag
     6601 gaaaattaga atatctgtgt aaaataaaaa atatcaattt tattaggcaa gaagaaagct
     6661 atactagtaa atcagatttt tttgctgatg attttctacc tgatatcaat gtggacaatg
     6721 ttaaaaaata tgactttaaa ggggaaagaa taacacgtgg acagtacaaa tccagtgttg
     6781 gaatcattat aaatgcagat gtaaatgcga gttttaatat actaaaaaaa tcacaagtag
     6841 ttaatttatc taatttacag aataatcctc aaatattaaa gcaaccacag agagtaagaa
     6901 tatcttaatt atatttaaaa gataaactga tagcgtaagc ttacagctta gcggcgaatt
     6961 ggatccgcct tgttgtttac aacagaatct atttactttc gagtttatgg aatttcaaaa
     7021 atcactttta ctaaaaaggc ctaactataa taattaagag attagaaaac tggttataag
     7081 aggtgaaagt gtggaactat caaatataat agaaaagaat gaaataataa ctgtagttgg
     7141 agcaggagga aaaacttcgt ttataaacta ttttgcaaat ttttatagaa ataaattgaa
     7201 agttcttctt acaacaacaa ctaaaatata tgtaccaaac gattatgaca atataattat
     7261 tacaatagat ggaactgtta ttccatctat ttgtcatgga ataacagtct gtggcagtta
     7321 tataaataat gaaaataaat tagtaagtat tgattcctct attttggatg aaattgtaga
     7381 ccaatttgat ttagttttaa tagagggaga tggctcaaag agaaaaaaac ttaaaggttg
     7441 gaatgctaaa gaaccagtag tatatcatag aactacaaaa accataggga tattagatat
     7501 aacatcattt ggaatgaata ttaatgaaga gaatatacat agagtagaaa tatttaaaaa
     7561 aatagcaaat ttagatacaa gtagtattaa tagtagttct acagtaagta ttgaaaactt
     7621 aaaaaatata gtattaaatc caaatggatt atttaaaaat tattctggaa aaagagtatt
     7681 atttattaat aaagttgaaa atgaaaaata taaaaattta gctataaaat taatagaaaa
     7741 tattaaagaa tatgaaagtg aaatagagat attttatgga agtgtaaaac aaaaattttg
     7801 tgtaagatat tga
//
LOCUS       DAYAOO010000133         7771 bp    DNA     linear   BCT 12-OCT-2024
DEFINITION  TPA_asm: Clostridioides difficile isolate ST8-SSI-h139-18
            SAMN40601845-rid21577343.denovo.137, whole genome shotgun sequence.
ACCESSION   DAYAOO010000133 DAYAOO010000000
VERSION     DAYAOO010000133.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN40601845
            Sequence Read Archive: SRR28438827
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 7771)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7771)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-MAY-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-MAY-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002157583.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002157583.1
            Genome Coverage       :: 163x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/11/2024 16:19:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 4,038
            CDSs (total)                      :: 3,963
            Genes (coding)                    :: 3,930
            CDSs (with protein)               :: 3,930
            Genes (RNA)                       :: 75
            rRNAs                             :: 6, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 60
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 33
            CDSs (without protein)            :: 33
            Pseudo Genes (ambiguous residues) :: 0 of 33
            Pseudo Genes (frameshifted)       :: 7 of 33
            Pseudo Genes (incomplete)         :: 25 of 33
            Pseudo Genes (internal stop)      :: 11 of 33
            Pseudo Genes (multiple problems)  :: 8 of 33
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7771
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN40601845-rid21577343.denovo.137"
                     /isolate="ST8-SSI-h139-18"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Denmark"
                     /collection_date="2018"
                     /collected_by="Statens Serum Institute"
     gene            101..412
                     /locus_tag="ACGI5H_003629"
     CDS             101..412
                     /locus_tag="ACGI5H_003629"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896756.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004518 - nuclease activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GIY-YIG nuclease family protein"
                     /protein_id="HFG9699312.1"
                     /translation="MYFTYIIRCKDDSLYTGYTSNIVRRMNEHKLGINSKYTRAKGFE
                     KLEVYFVTNTKSNAMKLEYYIKKLTRNKKLSIIKNPSILINLIDNKEDYIIGKEIEQL
                     T"
     regulatory      505..597
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00059"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="TPP riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="thiamine pyrophosphate"
                     /db_xref="RFAM:RF00059"
     gene            697..1491
                     /gene="thiD"
                     /locus_tag="ACGI5H_003630"
     CDS             697..1491
                     /gene="thiD"
                     /locus_tag="ACGI5H_003630"
                     /EC_number="2.7.1.49"
                     /EC_number="2.7.4.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430015.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008902 - hydroxymethylpyrimidine kinase
                     activity [Evidence IEA];
                     GO_function: GO:0008972 - phosphomethylpyrimidine kinase
                     activity [Evidence IEA];
                     GO_process: GO:0009228 - thiamine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional hydroxymethylpyrimidine
                     kinase/phosphomethylpyrimidine kinase"
                     /protein_id="HFG9699313.1"
                     /translation="MSNYKIPTLTIAGSDSSGGAGIQADLKTFSAIGTYGMSVITAIT
                     AQNTKGVFAVEDLNKKIIKKQIEAVFEDIPPRAVKIGMVSSPEIILEIVENLKKYNPK
                     YLVVDPVMISKSGYYLLKPEAKENLIKYLIPLAYIITPNIPEAEEITGIKIHNVDDMK
                     RVGEEILQLGPKFVLMKGGHLDGEAVDILVGKNIFKVYKSERIDKKNTHGTGCTLSSA
                     ITSYLALGYEITEAVNLSKIYITEAIKRSFDIGHGVGPVHHFYKFE"
     gene            1515..2303
                     /gene="thiM"
                     /locus_tag="ACGI5H_003631"
     CDS             1515..2303
                     /gene="thiM"
                     /locus_tag="ACGI5H_003631"
                     /EC_number="2.7.1.50"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018112777.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004417 - hydroxyethylthiazole kinase
                     activity [Evidence IEA];
                     GO_process: GO:0009228 - thiamine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxyethylthiazole kinase"
                     /protein_id="HFG9699314.1"
                     /translation="MYNLIKDVKKLNPLVIHYTNNVTINDCANVTLAVGASPLMSFSY
                     EEVEEMVSVANSVVINIGTMNSNMLDLFLLAGKAANKYNKPVVLDPVGVFASKARAEL
                     TSRLLNEVKFSVVKGNVSEIKFIGGFNVRGKGVDSFDEEEDSTEIIRKIAEKLECVVV
                     ATGKIDIITNGKGTYKINNGTDKLKGITGTGCMTASLIASFMAVTENILEAATMGVLT
                     MSLSGELANLNNPPIGTFKENLMNAIYQMDIDALSKNSNIEFLN"
     gene            2326..2958
                     /gene="thiE"
                     /locus_tag="ACGI5H_003632"
     CDS             2326..2958
                     /gene="thiE"
                     /locus_tag="ACGI5H_003632"
                     /EC_number="2.5.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436488.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004789 - thiamine-phosphate
                     diphosphorylase activity [Evidence IEA];
                     GO_process: GO:0009228 - thiamine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="thiamine phosphate synthase"
                     /protein_id="HFG9699315.1"
                     /translation="MIDKESLKKCLKLYLVTDSEMLKGRDFYKCLEDAISSGITTVQL
                     REKNASGREFLRKAMKLREITKRYGVKFIINDRVDIALICDADGVHVGQSDIDVREVR
                     KLIGNNKILGVSARTLEEAICAKNDGADYLGVGSIFTTSTKLDAKSASFETVKEIKEK
                     VDMPFVLIGGINLDNIDKLKCLESDGYAIISAILKAEDISKEVEKWTLKI"
     gene            3097..3399
                     /locus_tag="ACGI5H_003633"
     CDS             3097..3399
                     /locus_tag="ACGI5H_003633"
                     /EC_number="2.7.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436486.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HFG9699316.1"
                     /translation="MIRILLVCVGGMSSTLLVNKMEKDAKKRNIDCKIWAVGEGDIKS
                     ELDNFDILLLGPQLRFMLDDVKSIVGDRAPVSIIDMVNYGTCNGHAVLNSVLEILK"
     gene            complement(3465..4214)
                     /locus_tag="ACGI5H_003634"
     CDS             complement(3465..4214)
                     /locus_tag="ACGI5H_003634"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889499.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HFG9699317.1"
                     /translation="MLNILWRSMKWRFKNPISFVVTILQPFLWLVLYSSIANQTMNNI
                     NINNYTAFILPGIIVLVVFSSCSSGGIINFIMKNSGSFYRVLIAPISRYSIVLGQLLE
                     AILVSFIEVTILCIVSIFFSVRIESGIGGILLMIVLIFMTAFFLSSLAYSISLLLPNE
                     IVYETIMTAIVLPIFFLSSALFPIESLSGGLKVAVMLNPFTHVINALRSLIFGETILI
                     GDIMPVILLFLILCCSSFSLAMWRLKKEMVS"
     gene            complement(4208..5170)
                     /locus_tag="ACGI5H_003635"
     CDS             complement(4208..5170)
                     /locus_tag="ACGI5H_003635"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896762.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HFG9699318.1"
                     /translation="MLAIEIDNLVKEYKNGVKALNGLSFNVNAGEIFSLLGPNGAGKS
                     SLINILTTFYKPTSGNVTMFGKDLVDNPSWIRTQIACVAQQISIDEHLSLMENMVFQS
                     KMYKVEPQIAKQRIDSLIDKFDLSSYLKYPTSSYSGGVKRRLDIAMNMVSSPKILFLD
                     EPTVGMDVDSRKSMWDMLLKIRDEYGTTIFLTTHYLEEAEQLSDNICIMKNGKDLAQG
                     TPSSLRSYIRQNILRITFHNTEDIKKYKDSIKSTGLVKFMSVRENSIFISVNDSRTAF
                     TLINKWLLEHDIEFDAIEIVEPSLEDVFLALTSSKKSLKEEWEC"
     gene            complement(5174..5632)
                     /locus_tag="ACGI5H_003636"
     CDS             complement(5174..5632)
                     /locus_tag="ACGI5H_003636"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728863.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GyrI-like domain-containing protein"
                     /protein_id="HFG9699319.1"
                     /translation="MNCKIEIKNIESVTVATMRYNGPMTEATKYFPNVFKAIKGKSNG
                     APFFCYYDVDQKTGVAEMELCVPTAETPNRMGITTKEFPKTKALFFTHTGSYSNLPKT
                     YEMIFKYIHENNIKIQTPWREVFIKGPGMLIKGNPDNYITEIIFPLKEEE"
     gene            5988..6344
                     /locus_tag="ACGI5H_003637"
     CDS             5988..6344
                     /locus_tag="ACGI5H_003637"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HFG9699320.1"
                     /translation="MNFELDNTTPIYLQIVKYIKRQIVTGELKPGETIPSRREMALNL
                     KVNLNTVQRAYKEMGDMNIINTFKNYQSSVTVDENILKNLKLELINESLSVFIEDMKA
                     INVSKEEVLKIIEDKY"
     gene            6416..7132
                     /locus_tag="ACGI5H_003638"
     CDS             6416..7132
                     /locus_tag="ACGI5H_003638"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905518.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HFG9699321.1"
                     /translation="MIEIKNVSKTYKRMQGLKIRKIEALKNVSFNIEKGKITALLGIN
                     GVGKSTMLKAIAGLINIDSGEIRIDGEKINEKVYNKLAFVPDVQSHFSNTTIKETFEF
                     MEIFYSKWNKEKSKEMMDIFKLDEDEIIDNLSKGNIARVKLILGFCQDPEYILLDEPF
                     TGIDLFKREEFIGVIAQYMEENQAIIITTHEIVEIESLVDEVVILDEGQIITSFNAEE
                     LREREGKSILDKMREVYKNE"
     gene            7125..>7771
                     /locus_tag="ACGI5H_003639"
     CDS             7125..>7771
                     /locus_tag="ACGI5H_003639"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430026.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HFG9699322.1"
                     /translation="MNKLLYLINVDLRRSNKFYIAYISFFSLITLSLNLFEINKFKNS
                     KFIMNLAIEDFGGIFYGLGILSNLGFIQSILFFGILGLFIYYIFMWKREFFSNNQSIY
                     TLMMLPQNKFKICISKSIALITMIYGFLISQTATLFICKYIFNFIFRNMPIINMNFAK
                     DLYYLNLKSIPIDFISFMAIHVFLLLIAISIVNCCILFIFSYINKFYVILITLLI"
BASE COUNT         3017 a          905 c         1263 g         2586 t
ORIGIN      
        1 tataattaat tctttgaaga ttgcatattc aaaatacaca ccattttttt taattctata
       61 atataatatt tatatattta atgttaggat gtgatttaag gtgtatttta catatattat
      121 aagatgtaaa gatgattctc tatacactgg atataccagt aatatagtta gaagaatgaa
      181 tgaacataaa ttaggaatta attcaaaata cacaagagca aagggatttg aaaaactaga
      241 agtttatttt gtgaccaaca caaaaagcaa tgctatgaag ttagaatact atataaaaaa
      301 attaactaga aataaaaaat tgtctataat aaaaaaccca agtatactta taaatttaat
      361 tgataataaa gaagattata ttattggtaa ggaaatagaa caattaacat aaatatttat
      421 agtaacatta taatgggtgc atatggtgta aaaacttgac aataaatact attgtaatat
      481 aatgaagtta taaatatagt aaattaaaat agctagggga gccaagagct gagaggtata
      541 ccgaccctta cacctgatct ggataatacc agcgtaggaa agcttagtaa aaattcaagt
      601 atgtattatt tgtgatatat gctatttcta agctatacct attgtaggta tagctttttt
      661 aattaagtta tttaaattaa actttaggag gcaacaatga gtaattataa aataccaaca
      721 cttacaatag ccggctctga ttcatctgga ggagctggga ttcaggctga tttgaaaacg
      781 tttagtgcaa ttggtactta tggtatgagt gtaataacag ctataacagc acagaatact
      841 aaaggagttt ttgctgtaga ggatttaaat aagaaaataa taaaaaaaca aatagaggca
      901 gtctttgaag atatacctcc aagagctgta aaaataggaa tggtttcaag tcctgagatt
      961 atacttgaaa tagttgagaa tctaaagaaa tacaatccaa aatatttggt tgtggaccca
     1021 gtaatgatat ctaaaagtgg atattatcta ttaaagccag aggcaaaaga aaacttaatt
     1081 aagtatttga taccacttgc atacataatt acaccaaata taccagaggc agaagaaata
     1141 acaggaataa aaatacataa tgtagatgat atgaagagag taggagaaga aatactacaa
     1201 cttggaccta aatttgtact tatgaaagga ggtcatttag atggagaagc agtggatatt
     1261 ttagttggta aaaatatatt taaagtttat aaaagtgaaa gaattgataa aaaaaataca
     1321 catggaacag ggtgcacatt atcttctgca ataacatctt atctagcatt aggatatgaa
     1381 ataacagaag cagtaaatct aagtaaaatc tatataacag aagcaataaa aagaagtttt
     1441 gatataggtc atggagtagg accagtacat catttttata aatttgagta ataaaaaaat
     1501 attggaggta gaatatgtat aatttaatta aagatgtaaa aaaattaaat ccattggtaa
     1561 ttcattatac taataatgta actataaatg attgtgctaa tgtaacttta gctgtaggag
     1621 caagtcctct tatgagtttt tcatatgagg aagtagaaga aatggtaagt gtagcaaact
     1681 ctgtagtaat aaatatagga actatgaact caaatatgtt ggatttattc ctattagctg
     1741 gaaaagcagc aaataagtac aataaacctg ttgttttgga cccagttgga gtatttgcaa
     1801 gcaaagcgag agcagaactt acaagtagac ttttaaatga agtcaaattt agtgttgtta
     1861 aagggaatgt atcagaaata aagtttatag gtggctttaa tgtaaggggt aaaggtgtag
     1921 attcatttga tgaagaagaa gattctactg agataataag aaagattgct gaaaagcttg
     1981 aatgtgtagt tgtagcaact ggaaaaatag atataataac taatggtaaa ggtacatata
     2041 aaataaacaa tggaactgat aaattaaaag gaattacagg aactggatgt atgactgcta
     2101 gcttgattgc aagttttatg gctgttactg agaatatatt agaagcagca acaatgggtg
     2161 ttcttacaat gtctttaagt ggggaattag ctaatttaaa taatccacca ataggtacat
     2221 ttaaagaaaa tcttatgaat gctatttatc aaatggatat agatgcttta agtaaaaatt
     2281 ctaatattga atttttaaat taataaagag taagggagac ttaaaatgat tgataaagaa
     2341 tctttaaaaa aatgtttaaa gttgtattta gtaactgact ctgaaatgct taaaggtaga
     2401 gacttttata aatgtcttga agatgcaata tcttctggaa taacaactgt acaacttaga
     2461 gaaaaaaatg cttctggaag agagttttta agaaaagcta tgaaacttag agaaataact
     2521 aaaagatatg gtgttaagtt tataataaat gatagagtgg atatagcact tatttgtgat
     2581 gcagatggag tacatgtagg acagagtgac attgatgtta gagaggttag aaagcttata
     2641 ggaaacaata aaattctagg agtatcagca agaactttag aagaagctat ttgtgcaaaa
     2701 aatgatggcg cagactattt aggtgtaggg tctatattca caacatctac taaattagat
     2761 gcaaaatcag cttcgtttga aactgttaaa gaaattaaag aaaaagtaga catgccattt
     2821 gtactaattg gaggtataaa tttagacaat atagataaac ttaaatgttt agaaagtgac
     2881 gggtatgcta taatatcagc tatattaaaa gctgaagata tctctaaaga agtggaaaag
     2941 tggacattaa aaatataaaa ttggctctgg tagtgaaaaa aatggaaaaa tttgatataa
     3001 tctaagagta aaatttaagc aattataaat gataaacttt tctacatata ctttttaatc
     3061 aagatatatg tagatttggt taaaaaggag ctataaatga ttaggatatt gttagtgtgt
     3121 gttggaggca tgtcttctac cctattggta aataaaatgg agaaggatgc aaaaaaaaga
     3181 aatatagact gtaaaatatg ggcagttgga gaaggagata taaaatcgga gcttgataac
     3241 tttgatattt tacttcttgg accacaactt agatttatgc ttgatgacgt aaagtctata
     3301 gttggagata gagctccagt atctataata gatatggtaa actatggcac ttgtaatggt
     3361 catgctgtgt taaattcggt tttagaaata ttaaaataaa taataaaagt ggattctata
     3421 taatagagtc catttttatt atttgttatt aataggctta aaacttagct taccatttct
     3481 ttttttaatc tccacatagc aagtgaaaaa cttgaacagc acaatattaa aaatagtagg
     3541 ataacaggca ttatatctcc aataagaata gtctcaccaa atattaagct acgtaaagcg
     3601 ttaataacat gggtaaatgg attgagcatc actgctactt ttaatcctcc agataaactt
     3661 tctataggga aaagagctga acttaaaaag aaaataggaa gtacaattgc agtcataatt
     3721 gtttcataaa ctatttcatt tggcaataat aaacttatag aataagctag acttgataaa
     3781 aagaaggctg tcataaatat cagtactatc ataagtagga ttccaccaat gccagattct
     3841 atccttactg agaagaatat acttactata cacaaaatag ttacttctat gaaagaaact
     3901 aagatagctt ctaataattg accaaggacg attgaatacc tgctgatagg tgcaattaag
     3961 actctataga aacttccact gttcttcatt ataaagttta taataccacc actactacaa
     4021 gaagaaaaca caaccagtac aatgatacct ggtagtataa aagcagtata attattgata
     4081 tttatattat tcatagtttg gtttgcaata gaactataaa gcacaagcca aagaaaaggt
     4141 tgtaatatag taactacaaa tgagattgga tttttaaaac gccacttcat actacgccat
     4201 aagatattta acattcccat tcctccttta agcttttttt agaacttgta agtgctaaaa
     4261 atacatcttc gagacttggc tctacaattt ctattgcatc aaattctata tcatgttcta
     4321 aaagccattt atttattaaa gtaaaagcag ttctactatc gtttacactt ataaaaattg
     4381 aattttctcg tacgctcata aactttacta aaccagtact tttaattgaa tctttatatt
     4441 tttttatatc ttcagtatta tgaaaagtta tacgtagtat attttgtcta atgtaactac
     4501 gtaaacttga tggtgttcct tgtgctaaat cctttccatt cttcataata caaatattat
     4561 cactcaattg ttcagcttct tcaagataat gagtagttag aaatatagtt gtgccatact
     4621 catctctaat ttttaataac atatcccaca tagattttct tgaatcgaca tccataccaa
     4681 cagttggttc atctaaaaat aggattttag gagatgatac catattcata gctatgtcca
     4741 atctacgttt tacaccccct gaatatgatg aagtaggata ttttaagtaa ctagataagt
     4801 caaacttatc aattaaagag tctattcttt gttttgcaat ctgtggttct actttataca
     4861 ttttactttg aaataccata ttttccataa gggataaatg ttcatcaata gagatttgct
     4921 gtgctacaca agcaatttga gtacgtatcc aagaaggatt atctactaaa tcttttccaa
     4981 acattgttac atttccagat gtaggtttgt aaaaggtagt caaaatattt ataagagaag
     5041 atttaccagc accattagga ccaagtaaag aaaaaatttc tccagcattt acattaaagc
     5101 ttagaccatt taaagctttc acaccatttt tatattcttt tactaaattg tctatttcaa
     5161 tcgctaacat atattattcc tcctctttaa gtggaaatat tatctctgta atatagttat
     5221 ctgggtttcc ttttatcaac atacctggtc ctttaataaa tacttctctc caaggagttt
     5281 gtatttttat attattttca tgaatatatt taaatatcat ttcatacgtt tttggcaaat
     5341 tactataaga gcctgtgtga gtaaaaaata aagcttttgt tttaggaaat tcttttgtag
     5401 ttatacccat acgatttgga gtttcagcag ttggaacaca taattccatt tctgcaacac
     5461 cagttttttg gtcaacatca tagtagcaaa agaatggtgc accgttagac tttcctttta
     5521 tagctttaaa tacatttgga aaatactttg ttgcctcagt cataggtcca ttataacgca
     5581 tggtagccac tgtgactgat tcgatatttt tgatttcaat tttgcaattc atttgtttac
     5641 ctcctaatgt gtgttcatat tcttactaga tttttaagca ttaatacata taagattttg
     5701 attagttgaa aacatataat cttatctcgt ttgcttgttt tcaagtctaa cataacataa
     5761 aatatatatc ctctcatttg atgctccatt ttgtaaagtt attatttaag ctttacttta
     5821 gattttttag caaattaaaa taaagcaatt tataaaataa gtatttacaa attaagtgta
     5881 ttaatcgtat aatacactta ataggatact agataaagtc tgaaataaag gcgtattttt
     5941 ttaaagtaag tgtactatcg tattaataca ctagaatagg aggaatcatg aattttgaat
     6001 tagataatac aactcccatt tatttgcaaa tagtaaagta tataaagaga caaatagtaa
     6061 caggagagtt gaaaccagga gagacaatac catcaagaag agaaatggca cttaatctaa
     6121 aagtaaactt aaatacagtt caaagagcat ataaggagat gggtgatatg aatataataa
     6181 atacttttaa aaattatcaa agcagtgtaa cagttgatga aaatatatta aaaaatttaa
     6241 aattagagct tataaatgaa tcactatctg tttttataga agatatgaaa gcaataaatg
     6301 ttagcaaaga agaagtttta aaaataatag aagataagta ttagtttttt aacaaataga
     6361 aaacttagtt tagaaagttt atttataagc atattggatg tggaggatag taaatatgat
     6421 agaaataaag aatgtcagca aaacatataa aaggatgcaa gggcttaaaa taagaaagat
     6481 agaagcttta aaaaatgtaa gttttaatat agaaaaggga aaaataactg cattacttgg
     6541 tataaatggt gttggtaaat caactatgtt aaaagcaata gcaggactta taaacattga
     6601 tagtggagaa attcgtatag atggagaaaa aataaatgaa aaggtataca ataaattggc
     6661 ttttgttcca gatgtacaat ctcactttag caatacaaca ataaaagaaa catttgaatt
     6721 tatggaaatt ttttattcaa agtggaataa agaaaaatca aaagaaatga tggacatatt
     6781 taaattggat gaagatgaaa taattgataa cttgtcaaaa ggaaacattg caagagtaaa
     6841 attaatactt ggattttgcc aagacccaga gtacatactt cttgatgaac catttacagg
     6901 aattgatttg tttaagaggg aagagtttat aggagtaata gcgcaatata tggaggaaaa
     6961 tcaagccatt attataacta ctcatgagat agtagagata gaaagtttag ttgatgaggt
     7021 tgtaattctt gatgaagggc agattataac ttcatttaat gcagaagaat taagagaaag
     7081 agaaggtaaa tctatattag ataagatgag ggaggtatat aagaatgaat aaacttctat
     7141 atctaataaa tgtagatttg agaagaagca ataagtttta tatagcttat atatcatttt
     7201 tttcattaat tacacttagt ttaaatttat tcgaaattaa taaatttaaa aattctaaat
     7261 ttattatgaa cttagcaata gaagattttg gaggtatatt ttatggacta gggatactta
     7321 gtaatcttgg ttttatccaa agtatattgt tctttgggat attgggactt tttatatact
     7381 atatttttat gtggaaaaga gagttctttt caaataatca aagtatttat acacttatga
     7441 tgttacctca aaataagttt aagatttgta tatctaaatc aatagccttg ataacaatga
     7501 tatatggttt tttgataagt cagacagcaa cattatttat atgtaaatat atatttaatt
     7561 tcatttttag aaatatgcct ataatcaata tgaactttgc caaagattta tattatttaa
     7621 acttgaagag tataccaatt gattttatct cttttatggc tattcatgta tttttactac
     7681 ttatagctat ttctattgta aattgctgta tattatttat cttttcctat ataaataaat
     7741 tttatgtaat tttaatcact ttgctgatta t
//
LOCUS       DAYAOO010000134         7753 bp    DNA     linear   BCT 12-OCT-2024
DEFINITION  TPA_asm: Clostridioides difficile isolate ST8-SSI-h139-18
            SAMN40601845-rid21577343.denovo.138, whole genome shotgun sequence.
ACCESSION   DAYAOO010000134 DAYAOO010000000
VERSION     DAYAOO010000134.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN40601845
            Sequence Read Archive: SRR28438827
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 7753)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7753)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-MAY-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-MAY-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002157583.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002157583.1
            Genome Coverage       :: 163x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/11/2024 16:19:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 4,038
            CDSs (total)                      :: 3,963
            Genes (coding)                    :: 3,930
            CDSs (with protein)               :: 3,930
            Genes (RNA)                       :: 75
            rRNAs                             :: 6, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 60
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 33
            CDSs (without protein)            :: 33
            Pseudo Genes (ambiguous residues) :: 0 of 33
            Pseudo Genes (frameshifted)       :: 7 of 33
            Pseudo Genes (incomplete)         :: 25 of 33
            Pseudo Genes (internal stop)      :: 11 of 33
            Pseudo Genes (multiple problems)  :: 8 of 33
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7753
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN40601845-rid21577343.denovo.138"
                     /isolate="ST8-SSI-h139-18"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Denmark"
                     /collection_date="2018"
                     /collected_by="Statens Serum Institute"
     gene            complement(259..2538)
                     /locus_tag="ACGI5H_003640"
     CDS             complement(259..2538)
                     /locus_tag="ACGI5H_003640"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EAL domain-containing protein"
                     /protein_id="HFG9699323.1"
                     /translation="MLSDAKNNRYGLSIIAVISILVITISCLIYGSRLNKTLGEETNQ
                     YLSEIANQSVNVLKKQINGDIKLLESISIFIEGEESFEVDNILSILKRQAINSSFKRM
                     GVILPNGTAYTTDGYIEDFSKRDYFLKSMQGEVVITGKLKDVIEDDKNTNSNINVYSV
                     PIYKDNEVKGVIFATHSTKLYEKILSVPTFNGKGYSYITRSNGDIVLNPSSKNANSTK
                     ENLFSYIGRSDSISKSSINNMKSNIKNFKSGSLSYSMFGKGYYLSYAPIGINDWYLFS
                     EVPKTAISEKSYAIIKLTLSACVVLIIIFTALTIYILFIHKKSKEKLEEFAFKDNVTG
                     IGNSNKFNLEGGKFLSSHEKKNLVLIYFDIDKFKLVNDRFGYEEGDRVLKEIAEIIKN
                     IFKEQSVFSRISNDNFAIIFEKKNNRESIIEICELIRKKLSMIKTSLGVELNLIPSIG
                     VYFVEEGETNISTCLDKAMIAKTTVKRKYLKVYEIYAENLKETLIEERDIEQEMHDAL
                     KNEQFKVYLQPKVDLSTTKIVGAEALVRWQHPKKGLISPGVFIPIFEKNGFITELDMF
                     VFTQVCKNFKRWENENFPTFPISINLSRVHLENPGFISELERITKEYEIEPNLIEIEL
                     TESAIFDNTKILFKIMQTLKSVGFKISMDDFGSGYSSLNMLKDMPIDVLKLDRQFFIT
                     VGNAKKSQIVVSSIVQMAKQLDIKVVSEGVETVEQAEFLRFIGCDMAQGFLFARPMPI
                     EEYEKLILDRYSLNRKETN"
     gene            complement(2809..4263)
                     /locus_tag="ACGI5H_003641"
     CDS             complement(2809..4263)
                     /locus_tag="ACGI5H_003641"
                     /EC_number="6.3.2.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454974.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016874 - ligase activity [Evidence IEA];
                     GO_process: GO:0008360 - regulation of cell shape
                     [Evidence IEA];
                     GO_process: GO:0009058 - biosynthetic process [Evidence
                     IEA];
                     GO_process: GO:0051301 - cell division [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--2,
                     6-diaminopimelate ligase"
                     /protein_id="HFG9699324.1"
                     /translation="MKLNDIIQGLDIINVKGELNIDINNVQYDSRKVTKGTLFICIKG
                     FVSDGHKYIKDAIEKGASAFLVEEDVAIKGCTFIKVKDTRKDMAKVADNFYNHPSQKF
                     NVIGVTGTNGKTSITTILNEILTLNKNKVGLIGTIKIFDGEKDIVSNSTTPESIDLQY
                     HFNNMLDNGCDYCAMEVSSHSLALNRVDETDFKLGIFTNLTPDHLDFHKDLEDYRKAK
                     EKLFFKTTMANIINIDDEGGKKIYENIKGINVPCYTYGVDTKADFMARDIKSDSDGVS
                     YRLITPSYEEVIFIPVPGMFTVYNTLAVIAACYVLGIPKPIYKEGLRLSNGVSGRFET
                     VPNDKGISVIVDYAHTPDALENVLKTTQQFAEGKIISVFGCGGDRDTEKRPLMGAIGQ
                     KYSDLCIITSDNPRTEEPEAIIKDILEGIDKKKENYHVVVDREQAIAEAISMAKKDDV
                     VIITGKGHETYQIIGKVKHHFDDKEVANECLSKM"
     gene            4358..5296
                     /locus_tag="ACGI5H_003642"
     CDS             4358..5296
                     /locus_tag="ACGI5H_003642"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012816320.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0043565 - sequence-specific DNA binding
                     [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="AraC family transcriptional regulator"
                     /protein_id="HFG9699325.1"
                     /translation="MKHCKKCSIIFYNITEERSSIKTMDNKIGYLNDNFKIFNIRDKK
                     DIQFEYHNHDFNKIIIFINGNVTYFVDGIPYKLKPWDILFISNNEIHKPVIDSNVFYE
                     RIAIWISPEFMKKNSDASSDLEKCFKIATENKCNRLRLNMHDIESIKSFIEQINISES
                     NTEFGNEILRNTLFIQLMIFLNRIFLKNENMESTEDVFYDETIKKVLNYINSNIDDKL
                     SIDSISSEFFISKYYLMRKFKSHTGTSIHNYIVQKRLILAKSLITNGHLMSEVCNKCG
                     FNDYSSFVRAFKKNYGVSPKNYINNKNPLDITLLDE"
     gene            complement(5509..7581)
                     /gene="ptsG"
                     /locus_tag="ACGI5H_003643"
     CDS             complement(5509..7581)
                     /gene="ptsG"
                     /locus_tag="ACGI5H_003643"
                     /EC_number="2.7.1.199"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416039.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0005355 - glucose transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:1904659 - glucose transmembrane transport
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-specific PTS transporter subunit IIBC"
                     /protein_id="HFG9699326.1"
                     /translation="MKKVFGVLQKVGKSLMLPVALLPAAGILLGVSNALAGDALLAHF
                     PALANPTFQLIISIMESSGQIIFNNLPLIFAVGVAVGLTEGEGVAALAAIVGFLILNT
                     SMGVMAGVTEDMVDNSMYANIVGIPTIQTGVFGGIIIGIVAAYLYKKFYKIELPQYLG
                     FFAGKRFVPIVTSLVAIAIGIILSFIWPPIQEGLLSFSKNVIEANQTLAAFMEGSLER
                     LLIPFGLHHVFHNPFWYQFGEYVNKAGELVMGDQKIFFAQLKDGVNFTAGTFMTGAFP
                     FMMFGLPAAALAMVHEAKPEKKKFVAGIMASAALTSFLTGITEPIEFAFLFVAPVLFA
                     IHCLFSGLSYAIMQLLGVKIGFTFSGGLIDFLLFGVLPNRTPWYLAILVGIGFAVLYY
                     SVFRFMIRKFNLKTPGREDESETNAEVIEMSKNELASEILIALGNKDNLKSLDACITR
                     LRLVVNDINKVDKEKLKSLGAAGVMVIGNNVQAIFGPKSDSIKSDIKDIIEGKTKVES
                     TVTKNVDKNKVKKNMEVANMENTLVEKIDSLTNGELLDIEEVPDSVFSSKLMGDGFAI
                     KSSDGLIYSPVDGTIGVIFPTKHAIIIKSQKSGVEILIHLGIETVNLEGNGFEVFVNV
                     GDEVKAGEKLVKMDLEYIEKNGLSTISPVVFTNLEQNQKLSIKKGVTTAKEENRVSIL
                     RDDIEKIG"
BASE COUNT         2633 a         1289 c          824 g         3007 t
ORIGIN      
        1 aaatatgtat aacacaccta tagaaattac tattattact atctaaagta ttttgctata
       61 atcccatata ctcttacctc aaaaacattc aaatgtaaaa aatactacat attaataaac
      121 tttgcccaat aattcctaaa ataatatcct aacaatgatt tatgttttta taatagtata
      181 tttttacata aaaaagtgaa cattgattaa caaagttcac ttttttataa atttttatgt
      241 tataattcac aattttattt aatttgtttc ttttctattt aaactatatc tatctaatat
      301 taatttttca tattcttcta ttggcattgg tctagcaaat aaaaatcctt gggccatatc
      361 acaacctata aaccttaaaa actctgcttg ctctacagtt tcaacacctt ctgaaacaac
      421 ttttatatca agttgctttg ccatttgaac aatacttgaa actacaattt gactcttttt
      481 tgcatttccc actgttataa agaattgcct atctaatttc aatacatcaa ttggcatatc
      541 tttaagcata tttaaagaag aataaccaga accaaaatca tccatagaaa ttttaaatcc
      601 aacagatttc aaagtttgca ttattttaaa taatattttt gtattgtcaa atattgcact
      661 ttctgtcaat tcaatctcaa ttaaatttgg ttcaatttca tattcttttg ttattctttc
      721 aagctcagaa ataaagcctg gattctcaag atgtactctt gataagttta ttgatatagg
      781 aaatgtgggg aaattttcat tttcccaacg tttaaaattt ttacaaactt gggtaaatac
      841 aaacatatcc aattctgtta taaaaccatt tttctcaaaa ataggaataa atacacctgg
      901 acttattaga ccttttttgg gatgttgcca acgtacaagt gcttcagcac ctacaatttt
      961 agtagttgat aaatcaacct taggctgtaa ataaacttta aattgttcat tttttaaagc
     1021 atcatgcatt tcttgttcaa tatcacgttc ttctatgaga gtttctttta aattttcagc
     1081 ataaatctca taaactttta aatattttct ttttactgta gtttttgcaa tcatagcttt
     1141 gtcaagacag gtagaaatat ttgtttctcc ctcttcaaca aaatatacac ctatggatgg
     1201 aattaaattg agttctactc ccaaacttgt ttttatcatt gacaattttt tacgtataag
     1261 ttcacatatt tctataattg actctctatt atttttcttt tcaaatatta tagcaaaatt
     1321 gtcatttgaa attcttgaaa atacagattg ctctttaaat atattcttaa ttatctctgc
     1381 tatttccttt aatactctat ctccttcttc atacccaaac ctatcattta ctagcttaaa
     1441 cttatctata tcaaaataaa ttaaaactag attctttttc tcatgagagg ataaaaattt
     1501 tcccccttca agattaaatt tatttgaatt gccaatacct gtaacgttat ctttaaaagc
     1561 aaattcttcc aatttttcct tactcttttt atgtataaat agtatataaa ttgttaatgc
     1621 cgtaaagatt ataatcaaga ctacacatgc tgataatgta agttttataa tagcatatga
     1681 tttctcagat atagcagttt taggaacttc agaaaaaaga taccaatcat tgattcctat
     1741 tggggcataa cttaaataat atccttttcc aaacatacta taacttaatg aacctgattt
     1801 aaagtttttt atatttgact tcatattgtt gatactagat tttgatattg aatcacttct
     1861 gccaatgtaa gaaaataaat tttctttagt agagttggcg tttttactgc ttggatttaa
     1921 aacaatatca ccattacttc tagttatata agaatatcct tttccattaa atgtaggtac
     1981 agaaagtatt ttttcataca acttcgtact atgtgtggca aatataactc ctttaacctc
     2041 attatcttta taaattggta cagaatatac attaatatta ctattggtat ttttatcatc
     2101 ttctattaca tcttttaatt ttcctgttat aaccacttct ccttgcattg attttaagaa
     2161 ataatctctt ttagagaagt cttctatata accatctgta gtgtatgctg taccatttgg
     2221 taaaataact cccattcttt taaatgaact attaatagct tgtcttttta gtatagaaag
     2281 gatattatct acttcaaaag actcttctcc ttcaataaat attgaaattg actctagtaa
     2341 ctttatatct ccattaattt gtttttttaa cacattgacg ctttgatttg ctatttctga
     2401 aagatattga ttcgtttctt cacctaatgt cttattcaac cttgaaccat aaatcaaaca
     2461 ggaaattgta attactaaga tacttatgac agcaattatg gacaaaccat acctattatt
     2521 ttttgcatca cttaacatta tgcttcctgc ctttctcgaa tctatgtatg tataatcatt
     2581 atcttatgac aattattgta aacattttat aataatactt atttttccat atttactgta
     2641 attatacaaa attataaact ttattacaac aataaattaa ttaatataga tattagtgtt
     2701 tacattattg cattatctat tttacaatta tttacatata aaaaaatgta atatcaaagt
     2761 gaagcttgat attacatttt tgttcttgta ttttgtttaa tttttatgct acatcttact
     2821 taaacactca tttgcaactt ctttatcatc aaaatgatgc ttaactttac ctataatttg
     2881 ataagtttca tgtcccttac ctgttataat tacaacatca tccttttttg ccatacttat
     2941 agcttctgct atagcttgtt ctctatcaac aacaacatgg taattttctt ttttcttgtc
     3001 aattccttca agtatatctt ttattattgc ctctggttct tcagttcttg gattatcaga
     3061 agttataata cataaatcag aatatttttg tccaattgct cccatcaaag gtctcttttc
     3121 agtatctcta tctccaccac acccaaacac agaaattatt tttccttctg caaattgttg
     3181 agttgtcttt agtacatttt caagtgcgtc aggagtatga gcatagtcta caattacgct
     3241 tataccttta tcatttggaa ctgtttcaaa ccttcctgat actccattag aaagtctaag
     3301 gccttcttta tatattggtt taggtatgcc aagtacatag caagcagcta taactgctaa
     3361 agtattatat actgtaaaca tccctggaac tggtataaat attacttctt catatgaagg
     3421 tgttattaat ctataagata ctccatccga atctgatttt atatctctag ccataaaatc
     3481 agccttagta tcaacaccat aagtgtaaca aggtacattt atacctttta tattttcata
     3541 tatctttttt ccaccttcat catctatgtt tattatattt gccatagtag tcttaaaaaa
     3601 taatttttct tttgcttttc tataatcctc taaatcttta tgaaaatcta aatggtctgg
     3661 tgttaaattt gtaaatatgc ctagtttaaa gtctgtttca tcaactctat ttaatgccaa
     3721 tgaatgtgat gaaacttcca ttgcacagta gtcacatcca ttatccaaca tattattaaa
     3781 atgatattgt aaatctatac tttctggagt tgttgaattg gaaacaatgt ctttttctcc
     3841 atcaaaaatt tttatagttc ctataagtcc aactttattc ttatttaaag ttaatatctc
     3901 atttagtata gtagttatac tagtttttcc attagtacct gtaactccta taacgttaaa
     3961 tttttgagat ggatgattgt aaaaattatc agctactttt gccatatctt ttcttgtatc
     4021 ttttaccttt ataaatgtac atccttttat tgctacatct tcttcaacaa gaaatgcact
     4081 tgctcccttt tctatggcat cttttatata cttatgacca tctgacacaa atccttttat
     4141 acatataaat aatgtacctt ttgtaacctt tcttgaatca tattgtacat tattaatatc
     4201 tatatttaat tcacccttga cattgattat atccaacccc tgtataatat catttaattt
     4261 cataaatgct ttcctccctt taaactcttt ctgctaaaat tacactacat ataatattat
     4321 attaagaatt ttttactatg tgaatggtta aaaatgcttg aaacattgca aaaaatgctc
     4381 tataattttc tataatataa ctgaggaaag gtcttctata aaaactatgg ataataaaat
     4441 cgggtactta aacgataact ttaaaatatt taatattaga gataaaaaag atatacaatt
     4501 tgaataccat aatcatgatt ttaataagat aattatattt ataaatggaa atgtaactta
     4561 ttttgttgat ggtattccct ataaactaaa gccttgggat atactcttta tcagcaataa
     4621 tgaaatccat aaaccagtta tagattcaaa tgtcttttat gagagaattg caatatggat
     4681 tagcccagaa tttatgaaaa aaaatagtga tgctagtagt gacttagaaa aatgttttaa
     4741 aatagctaca gagaataaat gcaatagatt gcgtttaaat atgcatgata ttgaatctat
     4801 taagagtttt attgagcaaa taaatatttc cgaatccaat actgaatttg gaaatgaaat
     4861 attgagaaat acattattta tacaacttat gatattctta aacagaattt tcctaaaaaa
     4921 tgaaaatatg gaatcaacag aagatgtttt ttatgatgaa actattaaga aagtattaaa
     4981 ctatataaat tcaaatatag atgataagct ttcaatagat agcatatcgt ctgaattttt
     5041 tataagtaag tattatctta tgagaaaatt taaatctcat actggaacgt ctatacacaa
     5101 ttatatagtt caaaaaagat taattttggc aaagtcacta ataaccaatg gtcaccttat
     5161 gagtgaagtt tgtaataaat gtggattcaa cgattattct agttttgtaa gggcatttaa
     5221 aaaaaactac ggtgtatctc ctaaaaatta tataaacaat aaaaatcctt tagatattac
     5281 tcttttagat gaatagataa tttatgtaaa ttttatttta ataaaacttg aagtattagt
     5341 gtatttatct tactaatacc tcaagttttt taatgtttta aaatatatca aaatataatg
     5401 atatatattt ctattactta aaatatatat taaataaatt gcatgttaac tgaacctatt
     5461 tatatattta ttaaatctca cataactttt agttacacta tcatatagct atcctatttt
     5521 ttcaatatca tctcttaata tacttactct attctcctct tttgctgtgg ttactccttt
     5581 tttaatgctt aatttctgat tttgttctaa attcgtaaat actacaggac ttattgttga
     5641 tagaccattt ttttcaatat attctaagtc cattttaact aatttttctc ccgcttttac
     5701 ttcatctcct acattcacaa atacttcaaa tccatttcct tctaagttta cagtttctat
     5761 ccctaaatgt ataagtattt ctactccact tttttgggat tttattatta ttgcatgctt
     5821 agttggaaat ataactccaa tagttccatc aactggtgaa taaatcaatc catcactaga
     5881 tttaattgca aatccatccc ccatcagttt acttgaaaat acagaatctg gcacttcttc
     5941 tatatctaat aactctccat ttgttaatga atcaatcttt tctactaaag tattttccat
     6001 atttgcaact tccatatttt ttttcacttt atttttatca acatttttag taacagtact
     6061 ttcaaccttt gtttttccct ctattatatc ttttatatca gactttattg aatctgattt
     6121 tggtccaaat atagcttgaa cattgttgcc aataaccata acacctgctg ctccaagtga
     6181 tttcaatttt tctttatcta ctttatttat atcatttaca accaatctaa gtcttgttat
     6241 acacgcatct agactcttta agttgtcttt atttcctaaa gcaatcaaaa tctctgatgc
     6301 taattcattc ttagacattt caatgacttc agcgttagtt tctgactcat cttctcttcc
     6361 tggtgtcttt aaattaaatt ttcttatcat aaatctaaat acactatagt ataatactgc
     6421 aaaaccaata cctaccaaga tagccaagta ccatggagtt ctattaggaa gaacaccaaa
     6481 taataagaaa tctattaatc ctcctgaaaa tgtgaatcca attttaactc ctaataattg
     6541 cataattgcg tatgataaac ctgaaaataa acaatgtatt gcaaataata ctggtgcaac
     6601 aaataaaaac gcaaactcta ttggctcggt tattcctgtt aaaaaagagg ttaatgctgc
     6661 tgatgccatt atacctgcta caaatttttt cttttctggc tttgcttcat gcaccatagc
     6721 aagagctgct gctggaagac caaacatcat aaatggaaat gcacctgtca taaaagtacc
     6781 tgctgtgaaa tttactccat ctttaagttg agcaaagaat atcttttggt cacccattac
     6841 aagctcacca gctttattta catattctcc aaattgatac caaaatggat tatggaaaac
     6901 atgatgcaaa ccaaatggta ttaatagtct ttccaaagaa ccttccataa atgctgctag
     6961 tgtttgattt gcttctataa cattttttga gaaactaagt aatccctctt gtattggagg
     7021 ccaaataaaa gacaatataa ttcctattgc tatagcaact aatgaagtaa cgattggtac
     7081 aaatctttta cctgcaaaaa aacctagata ctgaggtaat tcaattttat aaaacttttt
     7141 ataaagataa gcagccacta tccctataat aataccacca aatacccctg tttgaattgt
     7201 tggtattcca acaatatttg catacataga attgtctacc atatcttctg taacacctgc
     7261 cataacaccc atagatgtat tgagaattaa aaaacctact atggctgcca atgctgcaac
     7321 accttctcct tcagttaaac caacagctac cccaactgca aatataagtg gtaagttatt
     7381 aaatataatt tgacctgaac tttccattat acttattata agttgaaatg taggattcgc
     7441 caaagctgga aaatgagcca acaatgcgtc tcctgctaaa gcattactca cgccaagtaa
     7501 tatacctgct gcaggaagta atgcaactgg tagcattaga gattttccta ctttttgtaa
     7561 aacaccaaat acttttttca tttacttttc tctccttatt attttatatt tttttaaata
     7621 aaaaagactt aagtttataa aaagttacat tagtatactt aattctaaaa ttaaacttat
     7681 gttaatataa acaaacctat attaacctaa tttcagaatt aaaaataaac tattataatt
     7741 tttttataaa cat
//
LOCUS       DAYAOO010000135         7556 bp    DNA     linear   BCT 12-OCT-2024
DEFINITION  TPA_asm: Clostridioides difficile isolate ST8-SSI-h139-18
            SAMN40601845-rid21577343.denovo.139, whole genome shotgun sequence.
ACCESSION   DAYAOO010000135 DAYAOO010000000
VERSION     DAYAOO010000135.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN40601845
            Sequence Read Archive: SRR28438827
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 7556)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7556)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-MAY-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-MAY-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002157583.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002157583.1
            Genome Coverage       :: 163x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/11/2024 16:19:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 4,038
            CDSs (total)                      :: 3,963
            Genes (coding)                    :: 3,930
            CDSs (with protein)               :: 3,930
            Genes (RNA)                       :: 75
            rRNAs                             :: 6, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 60
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 33
            CDSs (without protein)            :: 33
            Pseudo Genes (ambiguous residues) :: 0 of 33
            Pseudo Genes (frameshifted)       :: 7 of 33
            Pseudo Genes (incomplete)         :: 25 of 33
            Pseudo Genes (internal stop)      :: 11 of 33
            Pseudo Genes (multiple problems)  :: 8 of 33
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7556
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN40601845-rid21577343.denovo.139"
                     /isolate="ST8-SSI-h139-18"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Denmark"
                     /collection_date="2018"
                     /collected_by="Statens Serum Institute"
     gene            322..1623
                     /locus_tag="ACGI5H_003644"
     CDS             322..1623
                     /locus_tag="ACGI5H_003644"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437698.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replicative DNA helicase"
                     /protein_id="HFG9699327.1"
                     /translation="MGKSKDVEIEKSILGTILLDNKLSYKLDELNENMFMNDICLEIF
                     KIMKELKKENIVIDVATVKSKIDRKSLAIKTSDVTNLITWGQNFGLDGHIKILKENLA
                     RRSINQNCQNLLHSLNLGENIDTCIYKFESNIKEILDKDTYENDDVNSIAGKVLDFLE
                     NKKDIGFKFGIKLLDTTIGGLFKGELTTIAAKSGVGKTALALQIMLNSFKQGKKTLFI
                     SREMTSEQVFMRNICRVTGVSTRNMKSKEIDENDWKLIVNAIGDLSENNLIYINDKID
                     TISAIRKRIRQVKPDLLIVDYVQLLTSQKSMDKREREVATFSRELKNMTLDFNIPVIQ
                     LSQLNDEMKDSRPYGDRPMRDSKAIYHDSNNVVYIHQLKGSDYEEAVRDIGESEEAVR
                     ASEYRGIKMVDLIVAKCRDGQTRHKHFCYFGDKLHFQELNY"
     gene            1699..1974
                     /locus_tag="ACGI5H_003645"
     CDS             1699..1974
                     /locus_tag="ACGI5H_003645"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418102.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Mor transcription activator family protein"
                     /protein_id="HFG9699328.1"
                     /translation="MLELRKIIELLEEHKIEVSIPKELHKYSLLEYLELCQQSGGTYF
                     YIKTLEGALKEARNELMIKLFNGKNYMELARMFEMSVINVRHIVRKK"
     gene            3145..3375
                     /locus_tag="ACGI5H_003646"
     CDS             3145..3375
                     /locus_tag="ACGI5H_003646"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418105.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HFG9699329.1"
                     /translation="MSNKKKKYANILANECVACGSCIKACPRSAISVPCGISAKINRD
                     LCVGCGICEKICPASVIEIITILKEEEGKCHE"
     gene            3368..3949
                     /locus_tag="ACGI5H_003647"
     CDS             3368..3949
                     /locus_tag="ACGI5H_003647"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418106.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4Fe-4S binding protein"
                     /protein_id="HFG9699330.1"
                     /translation="MNNKKHWYDYLWIFSSIYLILGFVNIIFAWIGLICFFVPLAISI
                     VKGNKAYCNKYCGRGQLFNLLGNKLKLSRNRDIPKFIRSKWFRYGFLTFFMVMFANML
                     FSTYLVFEGSRNFKEVVTLLWTIKMPWQWAYHGTLVSPWVVQFAFGFYSVMLTSTVLG
                     LITMILFKPRSWCVYCPMGTMTQMICKAKSKSV"
     gene            complement(4528..5205)
                     /locus_tag="ACGI5H_003648"
     CDS             complement(4528..5205)
                     /locus_tag="ACGI5H_003648"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895646.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_function: GO:0030552 - cAMP binding [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Crp/Fnr family transcriptional regulator"
                     /protein_id="HFG9699331.1"
                     /translation="MISQNEIDILTHSLPFWDKLTDLQKELLISSANTSHYKKGNPVH
                     CGDSDCIGILIIKSGTVRTYILSDEGREVTLFRLDDGDVCILSASCILKTITFDVYVD
                     AETDCDIIQISSSVFAKLSTENIHAELFSYKLATERFSDVMWAMQQILFMSFDKRLAS
                     FLIDEIAKNGSSTINMTHEQIAKYMGSAREVVSRMLKYFAREGIVSLSRGGIKVLDKD
                     KLRSLTL"
     gene            complement(5394..6758)
                     /locus_tag="ACGI5H_003649"
     CDS             complement(5394..6758)
                     /locus_tag="ACGI5H_003649"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902041.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0042910 - xenobiotic transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0006855 - xenobiotic transmembrane
                     transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MATE family efflux transporter"
                     /protein_id="HFG9699332.1"
                     /translation="MKESNKRIELLGSAPISKALLSMGLPTMIGMMITALYNLVDAYF
                     VGGLGTSQMGAISVAFPLGQLVVGLGLLFGNGAASYVARLLGHGDNEKAGKVVSTSIY
                     SSIIVGTLVIIVIMIFLNPILKLLGATKSIMPYAISYASIYVVSSIFNIFNVTMTNIV
                     TSEGAAKTTMCAMLLGALLNMILDPIFIYTFGLGVRGASIATAISQIASTLVYVGYIL
                     SKKSIFSFRINECCFSKEIFSEILKIGIPTLIFQLLTSLAITLTNMEATKYGDSVIAG
                     MGAVTRITSLGSLVVFGFIKGFQPIAGYNFGSKNYDRLHIAIKTSILWTTVFCVVLGL
                     ILILFPKSIISQFTSGDILLIENGSKALRANGFSFMLFGFYTVYSTLFLALGKAKEGG
                     FLGMCRQGVCFIPIILIIPVFYGLNGILYAQPIADLMAAIIAGFMSIRLHKELNLLKI
                     NGMH"
     gene            6886..7407
                     /locus_tag="ACGI5H_003650"
     CDS             6886..7407
                     /locus_tag="ACGI5H_003650"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888420.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PadR family transcriptional regulator"
                     /protein_id="HFG9699333.1"
                     /translation="MATIDLIVLGIVKQQPKSAYDIQKAVEYRNISRWVKISTPSIYK
                     KVIQLEQKGYIESKTVKNGKMPEKAVYSLTELGETHFLDLMFDTSSKPINILLDFNAV
                     IVNLNSLTPEKQKLCLNNIEENVQELKKTIEENISIKTEVPDTAKAVLEQQLVLAQAL
                     ETWINSLKDNMGN"
BASE COUNT         2951 a          867 c         1296 g         2442 t
ORIGIN      
        1 gagtaatgaa ttatattgaa cgatatatca ataattggca gtaagttata tcaaataaga
       61 tattactatc gagtaatgaa ttatattgaa caatatatta ataattggca gtaagttata
      121 tcaaataaga tattgctatt atgtagtaaa ttatataaaa caatgtatca gaataaatag
      181 tatattaata atttgtagta tatcatgacg aataatacag tcataacaaa tagtgagtca
      241 taacaaataa tgtatttata attgataatg tatttaaaaa tcaaaatata aaaacttata
      301 aggaaagaga gattaattta tatgggtaaa tcaaaagatg ttgaaataga gaagtctatt
      361 ttaggcacaa ttcttttaga caataaatta agctataagc tagatgaatt aaatgaaaac
      421 atgtttatga atgatatatg tcttgagata tttaaaatta tgaaagaact taaaaaagaa
      481 aacatagtga ttgatgtggc cactgtgaaa tcaaagatag atagaaaatc tctagcaata
      541 aaaacaagtg atgtgactaa tctaattact tggggtcaga attttggtct tgatggtcat
      601 attaaaattt taaaagaaaa tttagctaga agaagcataa atcaaaactg ccaaaacctt
      661 ttacacagcc taaaccttgg agaaaatatc gatacttgta tttacaaatt tgaaagtaat
      721 ataaaggaga ttttggacaa ggatacttat gaaaatgatg atgtaaatag tatagcaggg
      781 aaggtgcttg attttttaga aaacaaaaaa gatattggat ttaaatttgg tataaaatta
      841 cttgatacca ctataggagg tctttttaaa ggagagctaa ccacaatagc agctaaatcg
      901 ggggttggga agactgcttt ggcacttcaa ataatgttaa attcatttaa gcaaggtaaa
      961 aaaactttat ttataagtag agaaatgacc agtgagcaag tatttatgag aaatatatgc
     1021 agagtaactg gtgtaagtac aaggaatatg aaatctaaag aaatagatga aaatgattgg
     1081 aaacttattg taaatgcgat aggtgattta agcgaaaata acttaattta tatcaatgat
     1141 aagatagata caattagtgc aattagaaag aggataaggc aggtaaagcc agatttatta
     1201 atagtggatt atgtgcaact ccttacatct cagaaaagca tggataagag agaaagggag
     1261 gtagctactt tttcgagaga acttaaaaat atgactttag attttaatat acctgtaatc
     1321 caattaagtc agttaaatga tgaaatgaaa gattcaagac cttatggaga tagacctatg
     1381 agggatagca aagccatcta ccacgatagc aacaatgtgg tttatataca tcaattaaag
     1441 gggagtgatt atgaagaagc agtgagagat attggagaaa gtgaggaggc agttagagca
     1501 tcagaataca ggggaattaa gatggttgat ttaatagttg cgaagtgtag agatggacag
     1561 actaggcata agcatttttg ttactttggg gataagttac attttcaaga actaaattat
     1621 taggtcaata aagtagtaat aacaagctta ttaaaagtcg ggaaatagca aatagattat
     1681 aaaatatgag gtgaaaatat gttggaatta agaaaaatta tagaattact tgaagaacac
     1741 aagatagaag taagtattcc aaaggagtta cataagtata gtttattgga ataccttgaa
     1801 ttgtgtcaac aaagtggggg aacatatttt tatattaaaa cactggaagg ggctttaaaa
     1861 gaggctagaa atgagcttat gattaaattg tttaatggga aaaattatat ggaattagcg
     1921 aggatgtttg aaatgagtgt tattaatgtc aggcatattg ttagaaaaaa atagatattt
     1981 ttggagaata caagtgtgat atacttctga aatagaagtt attataagag gagtataagt
     2041 gtgattaaca acatgatttt gtgaataaaa ttgaggatat atatgagtta aatgtgtgat
     2101 taataaggta agattgtgta taagattatg agtatttaaa aggaggggct ataattaata
     2161 gtgtagagtt gtgtgtttgc ttaagattat ataataattt aatagattaa actatactaa
     2221 taaggtaaaa tcgtgtgttt agttaaagct tattataaaa tcttgatatg tgattaatga
     2281 tgcaatatgt gaataaagtt aagattataa tagatttaac ctgtggctaa tagaataaaa
     2341 ttgtgaataa agttaagatt ataataggtt taaattgtga ctaatagagt aagagtgtaa
     2401 atagagataa acttcaatat gagcttaacc tatgattaat agagtaagaa tgtaaataga
     2461 gataaacttc aatatgagtt taacttgtgg ctaatagagt aagagtgtaa ctaaagataa
     2521 acttcaatat gggtttaact tgtggttaat agagtaagaa tgtaaataga gataaacttc
     2581 aatatgagct taacttgtga ttaatagagt aagagtgtaa atagagataa acttcaatat
     2641 gggattaact tgtgattaat agagtaagag tgtaactaaa gataaacttc aatatgagct
     2701 taacctatga ttaatagagt aagaatgtaa atagagataa acttcaatat gggtttaacc
     2761 tgtggttaat agagtagggt gtaactaaag ataaacttca atatgagttt aacttgtggc
     2821 taatagaata agattgtgaa taaagttata gttttagatg ggtattaacc tgttactaat
     2881 agaatatgat taggtgtaaa attatagagc tgcataagaa aatattatag atatattaaa
     2941 tattagataa taaatattta tatagataca caaaagaaaa ggcgatatga agctaaactt
     3001 aatgacttca tatcgttttt tatttgaaac tcctttgtat ttagagtgtg atttttaata
     3061 ttgaggtttt atgtgattaa gtcacagata aaaagtaagt atcttgatat aattcttata
     3121 gattaataat atagggaggt tattatgtct aataaaaaaa agaagtatgc aaatatttta
     3181 gcaaatgagt gcgttgcttg tggtagctgt ataaaagcat gtccaagaag tgctatctca
     3241 gttccatgtg gcattagtgc aaaaattaat agagatttat gtgttggatg tgggatttgt
     3301 gaaaagatat gtccagcatc tgtaattgag attataacaa tattaaaaga ggaagaaggt
     3361 aagtgtcatg aataataaaa aacattggta tgactattta tggatttttt cttcaatata
     3421 tttgatattg ggatttgtaa atattatttt cgcttggatt gggctaattt gtttctttgt
     3481 tccactagct atttctattg ttaagggaaa taaagcttac tgtaataagt attgtggaag
     3541 agggcaactg tttaatttgc ttggaaataa attgaagctg tcaagaaata gagatattcc
     3601 taaatttatt agaagtaagt ggtttagata tgggtttttg acatttttta tggtaatgtt
     3661 tgccaatatg cttttttcaa cttatttagt gtttgaagga agtagaaatt ttaaagaagt
     3721 agtgactttg ttgtggacta taaaaatgcc ttggcaatgg gcgtatcatg gaactttagt
     3781 ttcaccttgg gtggtacagt ttgcatttgg tttttatagt gttatgctta catcaactgt
     3841 tcttggtttg attactatga tattgtttaa acctcgttca tggtgtgttt attgccctat
     3901 gggtactatg actcagatga tatgtaaggc aaagagtaag tctgtataga aaggccttat
     3961 gtgatattta cagttttgtt caagtagaga tgagtagtag gtttgaatat atatgacaaa
     4021 tatatgagta taggggcata gatttagttt gtgtaaggta aactgattta tgcttctttt
     4081 ttatgtctta gattattggc taagtggaaa caatgaattt agatattaag aattattcag
     4141 ttatttgaag aaaatagaat aataattaac attatattaa tggatattca ttacatataa
     4201 gccagttaat agcaagattt atttaatatg atataggtca agtatttaaa ctaaataagg
     4261 tcatgacaat taatataagt atagatataa aaagattaga agttataact tataaaaggt
     4321 attctatata aatagtatgg ggaaaatagt caaattaact tattagaaac aaaaaatata
     4381 cataaaaaat aaatgtaaat atcaaataag atactatatc aaaatagata taagtatctt
     4441 ttttattatt gaaattatga aaatatattt gattttacac aaaaaagagt gcctcatgaa
     4501 ctaaaaagtt cattttgaga cacactttta cagtgtcaaa gaacgaagtt tatccttatc
     4561 caataccttt ataccaccac gagataaaga cacaatacct tctctagcaa aatatttcaa
     4621 cattctcgat acaacttctc tggcactacc catatactta gcaatttgct catgagtcat
     4681 atttatagtg ctactgccat ttttagctat ctcatcaatt aaaaaagatg ccaaacgctt
     4741 atcaaaactc ataaaaagaa tttgttgcat agcccacata acatcagaaa aacgttcagt
     4801 agctaattta tatgaaaata actctgcatg aatattttct gtagataatt ttgcaaaaac
     4861 agaggaacta atctgtataa tatcgcagtc cgtttcagca tctacataga catcaaaagt
     4921 tattgttttt agaatacagg aagctgataa aatacataca tctccatcat caagtcggaa
     4981 cagtgtaacc tctcgacctt catctgaaag tatgtatgta cgcactgttc cagattttat
     5041 aatcaaaata ccaatacagt cactatcacc acaatgtact ggattccctt ttttgtaatg
     5101 cgaggtattt gctgaagaaa ttaataattc tttttgtaag tcagtaagtt tatcccaaaa
     5161 aggcaagcta tgtgtaagta tatcaatttc attttgtgaa atcatacaat atctcctttc
     5221 ttaaattgtt ataatcccat gatacaagtg aatagataaa ttgacaagta gtttgttaag
     5281 aggattattt agtcagatag taatagtatg atttatgtag aaaaaatatg ataatatata
     5341 ttcttgctat taatgagaaa gtaatatgtt ttgatgatag taggtttgta taactaatgc
     5401 ataccgttta tttttaaaag attaagttcc ttatgtaacc ttatagacat aaaaccagca
     5461 attatagcag ccatcaaatc agctattggt tgtgcatata agataccatt taacccatag
     5521 aatacaggaa taatcaaaat tatagggata aaacagacac cttgtctaca catacctaaa
     5581 aatccacctt cctttgcttt tcctagtgcg aggaataatg tagaatacac tgtatagaat
     5641 ccaaatagca taaatgaaaa cccatttgcc ctaagagctt tactaccatt ttctattaat
     5701 aaaatgtcac cacttgtaaa ttgtgaaatt atagattttg ggaagagtat caatataaga
     5761 ccaagcacta cacaaaatac tgtagtccat aatatggaag tttttattgc tatatgtaat
     5821 ctatcgtagt tctttgaacc aaaattataa ccagcaattg gttggaaacc ttttataaaa
     5881 ccaaatacaa caagactacc taaagacgtt attcgtgtta cagcacccat tccagctatc
     5941 acagaatcac catactttgt agcctccata ttagttaatg taatagcaag actagtcaat
     6001 aattgaaata ttaaggtagg tatgccaatt tttaggattt ctgaaaaaat ttcttttgaa
     6061 aaacagcatt cgttaattct aaaactaaat atacttttct tgcttaaaat atatcctaca
     6121 taaacaagtg ttgaagcaat ctgtgagata gctgttgcaa tagaagcacc ccttaccccc
     6181 agaccaaaag tataaatgaa tatcgggtct aaaatcatat taagcaaagc acctaataac
     6241 atagcacaca tagttgtttt agcagctcct tcacttgtga caatattagt catagtgaca
     6301 ttgaatatat taaaaataga tgacacgaca taaatgctag cataagatat tgcataaggc
     6361 ataatacttt ttgtagctcc taacaatttt aaaattggat tgagaaaaat cataatcaca
     6421 ataataacta atgtacccac tataatacta ctgtaaatag atgtacttac cacttttcct
     6481 gctttttcat tatcaccatg gcctaaaagt ctggcaacat atgaagcagc tccatttcca
     6541 aacaataatc ctaatcccac aacaagctga cctaatggaa atgcaacgga tatagctccc
     6601 atttgacttg ttccaagtcc acccacaaag tatgcatcaa ccaaattgta taatgcagtt
     6661 atcatcatac ctatcatggt aggtaatccc atagataaca atgcttttga gattggggca
     6721 gaccctaata attcaattct tttgttactt tctttcatac ttaacactcc tcttctattg
     6781 acattaagtc taaattataa tactataaat tatagtaagt atggaaaata gtactataat
     6841 ttatagtatt tgtcaatagt aagaaaacta aaggagatga tttttatggc tacaatagat
     6901 ttaattgtat tgggaatagt aaagcaacaa cccaagagtg cttatgatat tcaaaaggca
     6961 gtggaataca ggaatatatc acgttgggtt aaaataagta caccatcaat ttataaaaaa
     7021 gtaattcaat tagaacaaaa gggatatatt gaaagtaaaa ctgtgaagaa tggaaaaatg
     7081 ccagaaaaag cagtttattc attaactgaa ttaggtgaga cacatttttt agatttaatg
     7141 tttgatacat ctagcaaacc aataaatatt cttttagatt ttaatgctgt tatagtaaat
     7201 ttaaatagcc ttacaccaga aaaacagaaa ttatgtctca ataatattga agagaatgtt
     7261 caagagttaa agaaaactat tgaggaaaat ataagtataa agacagaagt accagacaca
     7321 gcaaaagcag tgttggagca acagttggtg ctagcacaag cattggaaac ctggataaat
     7381 tctttaaaag ataatatggg aaattagaat tagagaagct aacttaataa tcattaaaca
     7441 aaaaccagca tatttaataa tgagatatta gaaaaaataa aacaaatgat ataaactgaa
     7501 aagtatattt aaaataaagc tcacttaatt gagggagaat gttaaacttt ttaaga
//
LOCUS       DAYAOO010000136         7468 bp    DNA     linear   BCT 12-OCT-2024
DEFINITION  TPA_asm: Clostridioides difficile isolate ST8-SSI-h139-18
            SAMN40601845-rid21577343.denovo.140, whole genome shotgun sequence.
ACCESSION   DAYAOO010000136 DAYAOO010000000
VERSION     DAYAOO010000136.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN40601845
            Sequence Read Archive: SRR28438827
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 7468)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7468)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-MAY-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-MAY-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002157583.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002157583.1
            Genome Coverage       :: 163x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/11/2024 16:19:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 4,038
            CDSs (total)                      :: 3,963
            Genes (coding)                    :: 3,930
            CDSs (with protein)               :: 3,930
            Genes (RNA)                       :: 75
            rRNAs                             :: 6, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 60
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 33
            CDSs (without protein)            :: 33
            Pseudo Genes (ambiguous residues) :: 0 of 33
            Pseudo Genes (frameshifted)       :: 7 of 33
            Pseudo Genes (incomplete)         :: 25 of 33
            Pseudo Genes (internal stop)      :: 11 of 33
            Pseudo Genes (multiple problems)  :: 8 of 33
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7468
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN40601845-rid21577343.denovo.140"
                     /isolate="ST8-SSI-h139-18"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Denmark"
                     /collection_date="2018"
                     /collected_by="Statens Serum Institute"
     gene            99..1076
                     /locus_tag="ACGI5H_003651"
     CDS             99..1076
                     /locus_tag="ACGI5H_003651"
                     /EC_number="6.3.4.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422214.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004077 - biotin-[acetyl-CoA-carboxylase]
                     ligase activity [Evidence IEA];
                     GO_process: GO:0036211 - protein modification process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="biotin--[acetyl-CoA-carboxylase] ligase"
                     /protein_id="HFG9699334.1"
                     /translation="MRDKIIEIILNNKSEFISGEELSKQLGVSRAAIWKHMKALKEEG
                     YNIESVNKKGYRLAENPTDLLSPQNIYYKLDTEFIGKNIEHLDTIDSTNEHAKRIAIN
                     SVDGTVILSEHQDMGKGRLGRRWDSKPHEGIWMSIILKPDMEPFKAPFITLIAGASVT
                     KALNNLGANTLIKWPNDVILNGKKICGILTELSAEIERTNYVVLGIGINVKIMDFEQE
                     IADKATSLYKEGYMLSRVDIVRNVLTEFEKLYLDYTVNNSKEKTLKICRDYSAIIDKN
                     IYVLKGDNRELVKCLDINEEGNLLVQRSDGSIKEIISGEVSIRGEKGYV"
     gene            1069..2037
                     /locus_tag="ACGI5H_003652"
     CDS             1069..2037
                     /locus_tag="ACGI5H_003652"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892121.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="P1 family peptidase"
                     /protein_id="HFG9699335.1"
                     /translation="MYNNILDIEGLKVGQVEDRNGLTGCTVVICEEGATCGVDVRGSA
                     PGTRETDLLDPVNMVQKVHAVVLAGGSAYGLESTCGVSRYLEEKGIGFDVGVGKVPIV
                     VGAVLFDLGVGSFKCRPDLKMGYRACEVANTDILNQGNYGAGCGATVGKIRGQEYAMK
                     GGIGSYSIKLDNGLIVSALIAVNALGDVYENGKVIAGALNDKKTETIDTYKLMKQGES
                     KGGFSVDNTTIGIIATNAKLTKAGCKKISQMGHDGYAKSIFPIHTPHDGDTIFTISTG
                     EIEADITLVGSLAVEVVEKSIINAVKKADSVENIMAYKDIVKKREI"
     gene            2220..2810
                     /locus_tag="ACGI5H_003653"
     CDS             2220..2810
                     /locus_tag="ACGI5H_003653"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892118.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HFG9699336.1"
                     /translation="MMNTSASVRKVNVRKMTIIGVLSAISIMLSMTPLGFIPVGPTKA
                     TIMHIPVIIGAIMEGPIVGAAIGFIFGISSLLNAITNPTATSFVFINPLVSILPRVMI
                     GVLAYYVYQLIIKATNKVYISGLITGAIGSLLNTAGVLGMIYVLYADKYLHAMGKSGS
                     AGKVIMALAAANGVPEAIVGALVVAAVATVLKKSKK"
     gene            2829..3599
                     /locus_tag="ACGI5H_003654"
     CDS             2829..3599
                     /locus_tag="ACGI5H_003654"
                     /EC_number="2.7.1.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861999.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004594 - pantothenate kinase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type III pantothenate kinase"
                     /protein_id="HFG9699337.1"
                     /translation="MLLVFDVGNTNMVLGIYKGDKLVNYWRIKTDREKTSDEYGILIS
                     NLFDYDNVNISDIDDVIISSVVPNVMHSLENFCIKYCKKQPLIVGPGIKTGLNIKYDN
                     PKQVGADRIVNAVAGIEKYGAPSILVDFGTATTFCAISEKGEYLGGTIAPGIKISSEA
                     LFQSASKLPRVELAKPGMTICKSTVSAMQSGIIYGYVGLVDKIISMMKKELNCDDVKV
                     IATGGLAKLIASETKSIDYVDGFLTLEGLRIIYEKNQE"
     gene            3736..4704
                     /gene="dusB"
                     /locus_tag="ACGI5H_003655"
     CDS             3736..4704
                     /gene="dusB"
                     /locus_tag="ACGI5H_003655"
                     /EC_number="1.3.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434962.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0017150 - tRNA dihydrouridine synthase
                     activity [Evidence IEA];
                     GO_function: GO:0050660 - flavin adenine dinucleotide
                     binding [Evidence IEA];
                     GO_process: GO:0008033 - tRNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA dihydrouridine synthase DusB"
                     /protein_id="HFG9699338.1"
                     /translation="MKIGNLELKNKVFLSPMAGVTDLPFRLICKEQGCGLLYTEMING
                     KALCYDDENTKKMLKIEEEEHPVAVQIFGSEPEFMGRATEIMNDYSNEILDINMGCPA
                     PKVVKNGDGSALMKNPKLAEEVLRAVVKNSKKPVTLKIRKGWDDNSVNAVEIAKIAED
                     CGISALAIHGRTREQFYTGKADWDIIAEIKKNLSIPVIGNGDVFTIEDSINMLDKTGC
                     DAIMIGRGAQGNPWIFKRINHYMNTGEILPEPTLNEKISTAIKHLKLAVEEHGEYVAV
                     REMRKHIAWYLKGLRNSAKLRDEINKIEDYQEVVSKLEYYMEDSLT"
     gene            4813..5292
                     /gene="greA"
                     /locus_tag="ACGI5H_003656"
     CDS             4813..5292
                     /gene="greA"
                     /locus_tag="ACGI5H_003656"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422204.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0070063 - RNA polymerase binding [Evidence
                     IEA];
                     GO_process: GO:0032784 - regulation of DNA-templated
                     transcription elongation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="transcription elongation factor GreA"
                     /protein_id="HFG9699339.1"
                     /translation="MEENKEFLLTQEGYDKLEEELENLKVVKRKEVAERIKVAISFGD
                     LSENAEYDEAKKEQAQVEERILKLENMVRKAVIIDESKIDLNVVTIGSIVKVKDLEFD
                     EEVEYTIVGSTEADPYDGKISNESPVGKALLGRAAKEVVEVQVPDGVAKFEILEIRR"
     gene            5307..6836
                     /gene="lysS"
                     /locus_tag="ACGI5H_003657"
     CDS             5307..6836
                     /gene="lysS"
                     /locus_tag="ACGI5H_003657"
                     /EC_number="6.1.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434963.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0004824 - lysine-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006430 - lysyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="lysine--tRNA ligase"
                     /protein_id="HFG9699340.1"
                     /translation="MKNNQQSNEEAQIQEDLSEVLQVRRDKLKKLQESGRDPFKESRY
                     DRTHYSMDIKDNFDSLEGKTTKIAGRIMSKRIQGKAGFIDIQDQEGRIQSYVRLDAIG
                     EEEYSVFSTYDIGDIVGIEGEIFKTKKGEISVKAKSVVLLCKSLQVLPEKYHGLKDQE
                     LRYRQRYVDLIVNPEVKNAFLIRTKALKALRAYLDDRGFLEVETPILNTIAGGANARP
                     FITNHNTLHIPMYLRIANELYLKRLIVGGFDKVYEMGRMFRNEGMDLKHNPEYTAIEL
                     YQAYADYTDMMEITENVIAHMAEVATGSMIVNYQGTEINFTPPWKRMSMEDCVKEYSG
                     VDFSTINTDEEALEVAREKGIEIKPGMRRGEVINAFFEEFGEDKLIQPTFITHHPVEV
                     SPLSKRNVEDPRRTDRFEAFANKWELANAFSELNDPIDQKGRFIDQLRKRELGDDEAF
                     EMDEDFLKALEVGLPPTGGLGIGIDRVIMLLTNSPSIRDVLLFPTMKPIDNNPNKEEE
                     N"
     gene            7145..7339
                     /locus_tag="ACGI5H_003658"
     CDS             7145..7339
                     /locus_tag="ACGI5H_003658"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728535.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9699341.1"
                     /translation="MFQVINFLCLFCVGFLVLDVMIYFCKDAMDIFEGTTNVNKVKSI
                     NVWADRVRANSYSYENKIAK"
BASE COUNT         2980 a          755 c         1509 g         2224 t
ORIGIN      
        1 gaaatttaaa attaatagta ttaaaagtat attaataatg tataattatt tattagaaga
       61 aaataagtca tgaaattatg tcatattaga ggtgaaatat gagagataaa ataatagaga
      121 ttatattaaa taataaatct gaatttattt caggagaaga attatcaaaa caattagggg
      181 tgtcacgtgc agctatatgg aaacatatga aagccttaaa agaagaggga tataatatag
      241 aatctgtaaa taaaaaaggg tatcgattag cggaaaatcc aactgattta ttaagcccac
      301 agaatattta ctataaatta gatacagagt ttattggaaa aaatattgaa catcttgaca
      361 ctatagattc aacaaatgaa catgctaaaa ggatagctat aaatagtgta gatgggactg
      421 tgattttaag tgaacatcaa gatatgggga aaggacgatt gggaagaaga tgggattcaa
      481 aacctcatga aggaatctgg atgagtatta tattaaaacc agatatggaa ccattcaaag
      541 ccccatttat aactttaata gcaggagcaa gtgtaacgaa agctttaaac aatctaggag
      601 caaatacatt aataaaatgg ccaaatgatg ttattttaaa tggaaaaaaa atatgtggta
      661 tattaacaga gttatctgct gaaattgaaa gaacaaatta tgttgttctt ggaattggaa
      721 taaatgttaa aataatggat tttgaacaag aaatagctga caaagccaca tcattgtata
      781 aagaaggata tatgttatcc agagtagata ttgttaggaa tgtattaact gaatttgaaa
      841 aattatattt agattatact gtaaataatt ccaaagaaaa aaccttaaaa atatgtagag
      901 attattctgc aattatagat aaaaatatat atgtattaaa aggagataat agagaactag
      961 tgaaatgttt agacataaat gaagagggaa atttattagt tcaaagaagt gatggaagta
     1021 taaaagaaat tatttcaggt gaagtttcta taagaggaga aaaaggatat gtataataat
     1081 attttggata tagaaggctt aaaggttggg caggttgagg atagaaatgg tcttactggg
     1141 tgcacagtag taatatgtga agaaggagct acttgcggtg ttgatgtaag gggctctgct
     1201 ccaggtacta gagaaaccga tttattagac cctgtaaata tggttcaaaa agttcatgca
     1261 gtagttttgg ctggaggttc tgcatatggt cttgaatcca cttgtggtgt aagtagatac
     1321 ttagaagaaa aaggaattgg ctttgatgta ggtgtaggta aagtgcctat agttgtagga
     1381 gcagttttat ttgatttagg agtagggagc tttaaatgta gaccagattt aaagatgggt
     1441 tatagagctt gtgaagttgc aaatactgat attttaaatc aaggaaatta tggagcaggt
     1501 tgtggagcca ctgttggaaa gataagaggt caggaatatg ctatgaaagg cggaataggt
     1561 agctattcta taaaattaga taatggtcta attgtatctg cattaattgc tgtaaatgct
     1621 cttggagatg tttatgaaaa tggtaaggtt atagctggtg ctttaaatga taaaaagaca
     1681 gaaacaattg atacatataa attaatgaaa caaggtgaaa gtaaaggtgg atttagtgta
     1741 gataatacta caattgggat aattgcaaca aatgctaagt taaccaaagc tggatgtaaa
     1801 aagatatctc aaatgggaca tgatggatat gctaagtcta tttttcctat ccatacacct
     1861 catgatggag atacaatatt cacaatatca acaggagaaa tagaagcaga tataacatta
     1921 gtaggttcat tggctgtaga ggttgtggaa aaaagtataa taaatgcagt aaaaaaagcg
     1981 gatagtgtag aaaatataat ggcatataaa gatatagtaa aaaaacgaga aatatgatga
     2041 aattagcata tttttcttgt caaattgttg acaatggcaa ctcatcttga taaaattatt
     2101 cttgttagag cgggcatcct acaatggtag cttgactcat agttataaga aaaaacgaaa
     2161 aaaattaaaa aattaagtag tccggcatct taatgagctg gaacggaggt gtatttttta
     2221 tgatgaacac aagtgcatca gtaagaaaag taaatgtaag aaagatgact ataataggag
     2281 tactatcagc tatttctatt atgctatcta tgactccatt gggatttatt ccagttggac
     2341 ctacaaaagc aactataatg cacataccag ttattattgg agctattatg gaaggaccaa
     2401 tagttggggc agcaatagga tttatatttg ggatatcaag tctcttaaat gctataacaa
     2461 acccaacagc aacatctttt gtttttataa atccattagt ttcaatatta ccaagagtta
     2521 tgataggtgt attagcttat tatgtatatc agttaataat taaggctaca aataaggtat
     2581 acatatcagg tttaattaca ggggcaatag gttctctgtt aaatacagct ggagttttag
     2641 gaatgatata tgtcttatat gctgacaagt atcttcatgc aatgggtaaa agtggttcag
     2701 caggaaaagt aataatggct cttgccgcag caaatggggt gccagaagca atagtagggg
     2761 ctttagtagt agctgctgtt gccactgtac ttaagaaaag caaaaaatag aaagaaggtt
     2821 aatgacatat gcttctagta tttgatgttg gaaatactaa tatggtttta ggtatatata
     2881 aaggtgacaa attagttaat tactggagaa ttaaaacaga tagggaaaaa acgtctgatg
     2941 aatatggaat cctgataagt aacctatttg attatgataa tgtgaatata agtgatattg
     3001 atgatgttat aatatcatct gtagttccga atgttatgca ttctcttgaa aacttttgta
     3061 taaagtactg taaaaaacag ccattaatag taggtccagg cataaaaaca ggtctaaata
     3121 taaaatatga taatccaaaa caagttgggg cagatagaat agttaatgct gtagcaggga
     3181 tagaaaagta tggagcacca agtatacttg ttgattttgg aacagcaact acattttgtg
     3241 ctatctctga aaaaggtgaa tatttgggtg gaacaatagc accaggaata aaaatatcta
     3301 gtgaggcgtt atttcaaagt gcgtctaaat tacctagagt agaattagct aagccaggta
     3361 tgactatttg taagagtact gtatcagcca tgcaatctgg aataatttat ggatatgttg
     3421 gtttagttga caaaataata agtatgatga agaaagaatt gaattgtgat gatgttaagg
     3481 ttatagctac aggtggatta gctaaactga ttgcttcaga gacgaaaagt atagattatg
     3541 tagatggttt tttaacacta gaaggattga gaataatata tgaaaaaaac caagaataat
     3601 taatatacag ggaattgggt tatatatcca attccctttt tatgatagat ttctagctat
     3661 atgtggtata ttataatgag gaaataagaa tttaaagtta aatcacaaaa taaaggcaaa
     3721 aataggagaa aaacaatgaa aataggaaat ttagaattga aaaataaagt ttttctatca
     3781 cctatggcag gtgtaacaga ccttccattt agattaattt gtaaagaaca aggatgtggg
     3841 cttttatata cagaaatgat aaatggtaag gcactttgct atgatgatga aaatactaaa
     3901 aaaatgctta agatagaaga ggaagaacat cctgtagcag ttcagatatt cggttcagaa
     3961 ccagagttta tgggaagagc aacagagata atgaatgatt attcaaatga gattctcgat
     4021 ataaatatgg ggtgtccagc tccaaaagta gttaaaaatg gagatggttc agcacttatg
     4081 aaaaatccta agcttgcaga agaggtattg agggcagtag tgaagaactc aaaaaagcca
     4141 gtgactttaa agattcgaaa aggctgggat gataatagtg taaatgctgt tgaaatagca
     4201 aagatagcag aggattgtgg aataagtgct ttagcaatac atggaagaac tagagaacag
     4261 ttttatacag gcaaagcaga ctgggatata attgcagaga ttaagaaaaa tttgagtata
     4321 cctgttatag gaaatggtga tgtatttaca atagaagatt caataaatat gttagacaaa
     4381 actggttgtg atgctataat gataggtagg ggtgctcaag gtaacccttg gatatttaaa
     4441 agaataaacc attatatgaa tacaggcgag attttgccag agccaactct taacgaaaaa
     4501 ataagtactg ccattaagca tttaaaactt gcagtagaag aacatggaga gtatgtagct
     4561 gtaagggaaa tgagaaaaca catcgcttgg tatttaaaag gacttagaaa ctctgcaaaa
     4621 ttaagggatg aaattaacaa aatagaagac tatcaagaag ttgtgtcgaa attggagtac
     4681 tatatggaag actccttgac ataaaaataa tagtgactta taatatagcg cataaattaa
     4741 aaaaagatta taaaattttt aaaatataat taggaaaatt cctaagaaat ttgtgaagga
     4801 gttgtattta taatggaaga aaataaagag tttttattga cacaagaggg atatgataaa
     4861 ttagaagaag aattagaaaa cttaaaggtt gtaaagagaa aagaagttgc agagagaata
     4921 aaagttgcta tatcttttgg tgatttatct gaaaatgctg agtatgatga agctaaaaag
     4981 gaacaagcac aagttgaaga aagaatttta aaattagaaa atatggttag aaaagctgtt
     5041 atcatagatg aaagcaaaat agaccttaat gttgttacaa taggatcaat agttaaagtt
     5101 aaggatttag aatttgatga agaggttgaa tatactatag ttggttcgac agaagcagac
     5161 ccatatgatg gtaaaatatc aaacgaatct cctgtaggga aagcactttt aggtagagct
     5221 gcgaaagaag ttgtggaagt gcaagttcct gatggagttg ctaagtttga aatattagaa
     5281 ataagaagat aatttggagg aaaaaaatga aaaataatca acaaagcaat gaagaagcgc
     5341 aaattcaaga agaccttagt gaagtacttc aagtaagaag agataaacta aaaaaattac
     5401 aagagtcagg tagagatcct tttaaagaaa gtagatatga tagaactcat tattctatgg
     5461 atataaaaga taactttgat tctcttgagg gtaaaactac aaaaatagca ggacgtataa
     5521 tgagcaagag aatacaaggg aaagctggct ttatagatat tcaagaccaa gagggaagaa
     5581 tccaatctta tgtaagacta gatgctatag gagaggaaga atatagtgta ttttcaacat
     5641 atgatattgg agatatagtt ggaattgaag gagaaatctt taaaactaaa aaaggtgaaa
     5701 tatctgtaaa ggctaaatct gtagtattac tatgtaaatc tttacaagtt ttaccagaaa
     5761 aatatcatgg attaaaagac caagaactaa gatatagaca aagatatgtt gacttaatag
     5821 taaatccaga agtaaaaaat gcttttttaa ttagaacaaa agcattaaaa gcattaagag
     5881 catacttaga tgatagagga tttttagaag ttgagactcc aatattaaat actatagcag
     5941 gtggggcaaa tgctagacca tttataacta atcataatac tttacatata ccaatgtatt
     6001 taagaatagc gaatgaattg tatttaaaaa gacttattgt tggtggattt gataaagttt
     6061 atgaaatggg aagaatgttt agaaatgaag gtatggattt aaaacataat cctgaatata
     6121 ctgcaataga attatatcaa gcatatgcag actatactga tatgatggaa ataacagaaa
     6181 atgttattgc acatatggct gaagttgcta caggaagtat gatagttaac tatcaaggaa
     6241 cagaaataaa ctttacacca ccttggaaaa gaatgagtat ggaagattgt gttaaagaat
     6301 attctggtgt agatttttct actataaata cagatgaaga ggcactagaa gttgctagag
     6361 aaaaaggtat agagataaaa cctggaatga gaagaggaga agtaataaat gctttctttg
     6421 aagaatttgg agaagataaa ttaatccaac caacatttat aactcaccat ccagttgaag
     6481 tatctccatt atctaagaga aatgttgaag acccaagaag aactgataga tttgaggcat
     6541 ttgctaataa gtgggagtta gctaatgcat tttctgaact taatgaccct attgaccaaa
     6601 aaggaagatt tatagaccaa ttgagaaaaa gagaattagg tgatgatgaa gcttttgaaa
     6661 tggatgaaga tttcttaaaa gcattagagg taggtctacc tcctacagga ggactaggaa
     6721 taggtataga tagagtaatt atgttattaa ctaactctcc atctataaga gatgtattat
     6781 tattcccgac tatgaaacct attgataaca atccaaataa agaagaagaa aactaagaaa
     6841 tattagcatt ctactaagtt ttaaataaag tttagctatt aaattatcaa taaatagcta
     6901 aattttattt aaaatgtcag tgtggaatgc tttttatatg cttcaaagat tcttttagat
     6961 atttaattta taaattacca acaaacgtta gaaattgata ttagtttttg ttgattgaga
     7021 ctttatattt agaaaatatg attgaaagta atttattatg aaaatattta gaataattta
     7081 tgagaaggta aaaagaataa tttatgagaa tactatatat aaaaaattat tgggggaatg
     7141 tctgatgttt caagtaatta attttttatg tttattttgt gttggatttt tggttcttga
     7201 tgttatgata tatttttgta aggatgcaat ggatattttt gagggtacaa ctaatgttaa
     7261 taaagttaag agtataaatg tttgggcaga tagagtgaga gctaattcat attcttatga
     7321 aaataaaatt gcaaaatagg taaaattata tatgcatgta ttgtttgtaa tatcaagggt
     7381 tatatctatt agttttaatt atatttatta aaaaaaccaa aagttataac cttttttaaa
     7441 ataaaaaaca aaaaaagtat tgacgaaa
//
LOCUS       DAYAOO010000137         7369 bp    DNA     linear   BCT 12-OCT-2024
DEFINITION  TPA_asm: Clostridioides difficile isolate ST8-SSI-h139-18
            SAMN40601845-rid21577343.denovo.141, whole genome shotgun sequence.
ACCESSION   DAYAOO010000137 DAYAOO010000000
VERSION     DAYAOO010000137.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN40601845
            Sequence Read Archive: SRR28438827
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 7369)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7369)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-MAY-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-MAY-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002157583.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002157583.1
            Genome Coverage       :: 163x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/11/2024 16:19:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 4,038
            CDSs (total)                      :: 3,963
            Genes (coding)                    :: 3,930
            CDSs (with protein)               :: 3,930
            Genes (RNA)                       :: 75
            rRNAs                             :: 6, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 60
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 33
            CDSs (without protein)            :: 33
            Pseudo Genes (ambiguous residues) :: 0 of 33
            Pseudo Genes (frameshifted)       :: 7 of 33
            Pseudo Genes (incomplete)         :: 25 of 33
            Pseudo Genes (internal stop)      :: 11 of 33
            Pseudo Genes (multiple problems)  :: 8 of 33
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7369
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN40601845-rid21577343.denovo.141"
                     /isolate="ST8-SSI-h139-18"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Denmark"
                     /collection_date="2018"
                     /collected_by="Statens Serum Institute"
     gene            114..764
                     /locus_tag="ACGI5H_003659"
     CDS             114..764
                     /locus_tag="ACGI5H_003659"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434477.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cyclic nucleotide-binding domain-containing
                     protein"
                     /protein_id="HFG9699342.1"
                     /translation="MKAEKTSIYPIIKNNLNKISIVEYKKGQRFVASDKDLQEVFFII
                     EGVALVECTTRGGNKFLVDIVPENEFIGKISYIYEHNLKCDIFAKTNIKLFRFEKNVF
                     EEFYLKPDFIALFHRKCTRRIYELYKTRMVRELFSCTEVIAYCISNKQENNVCNIKAI
                     RNFSEIYSISRKSRYHSLLKLTEKEIVKKMGNTYEILNYDELHKLAFEVKEFLEDE"
     gene            complement(904..2280)
                     /locus_tag="ACGI5H_003660"
     CDS             complement(904..2280)
                     /locus_tag="ACGI5H_003660"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425390.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0042910 - xenobiotic transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0006855 - xenobiotic transmembrane
                     transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MATE family efflux transporter"
                     /protein_id="HFG9699343.1"
                     /translation="MQELFSLKDENKRFYKILLSLCIPIIIQNLISTSVNVIDTIMIS
                     SLGETSVASVGVANQFFFLFNMSLSGITGGAGVFISQFYGKKDVSNIRKVTGLTCVLA
                     IVLSFVFVIPALLTPKPIIHIFSYDSEVVKLCIDYFSIAVFSYPLIAVSTVFSTGSRG
                     VRNPKLGMICSAFALVTNVILNYGFIFGNFGLPALGVKGAALATVIARICELILMITY
                     VYLYKKDYILKFGLKNLKAIDKIFIKSFSSKSFPIFVNDSVWAIGTVLYSVAYARAGT
                     SAIAASQIATSTGNFFIMTAVCIASGASIMLGNELGADHIKRAIEYAKKFSILVFSAG
                     LILGIILILNIPLLLKMFSVSDSLASDITKIFFIMGILMALKSFNTLVIIGILRSGGD
                     TKYALFLELGCMWLASIPLTFIAAFKGAPIFVLVLLTYSEEVVKFIFGVPRALSKKWA
                     INIVKEID"
     gene            complement(2296..4209)
                     /locus_tag="ACGI5H_003661"
     CDS             complement(2296..4209)
                     /locus_tag="ACGI5H_003661"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420835.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="HFG9699344.1"
                     /translation="MIVLSCNNLNKSFGIDSILENISFTVNEGDKIGIIGVNGTGKTT
                     LFKIISGIYGYDSGDIYTSKDCEIGYLEQNTNFYSDNTILEEVLEVFKNLIEMESYLR
                     ELEVKISEESTKTNSPIIEKIMDEYSHKLELFSDLNGYGYKSEAKGVLKGLGFSDNDM
                     DKPISILSGGEKTRVLLGKLLLKKPTLLLLDEPTNHLDSEAIEWLEVFLKQYKGTVML
                     ISHDRYFLDQSVNRIFEVHNKKLKVYNGNYSKFVELSKIEKELELKKFEDQQKEIKKQ
                     EESIERLKAYGREKHLKRARSKEKALDKVDVLDKPEAYRKKARIQFTPSVQSGNDVLQ
                     IRDVSMGYGERILFKDLDLDIYRGEKVALIGANGVGKSTLFKIITNELQPLSGNIKFG
                     TNVHVSYFHQEQKTLNLDNTIIDEIWENNTHLTQTTLRNMLGAFLFVDEEVFKKISTL
                     SGGERARVAILKLILSNANLLLLDEPTNHLDIDSKEVLEEALTNYDGTIFTISHDRYF
                     LNTVVDKILVLDENGITEYLGNYDYYIDKKRQIQEMSIIEEKEEKTRTQIKDEKRKER
                     EQREIEKKNRIKRQNIEKEIEKLEIEIEKLDILLCQEEVYSNPDKAKEVSQEKINLEN
                     NLASLYDEWEEFM"
     gene            4345..4977
                     /locus_tag="ACGI5H_003662"
     CDS             4345..4977
                     /locus_tag="ACGI5H_003662"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420839.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0045892 - negative regulation of
                     DNA-templated transcription [Evidence IEA];
                     GO_process: GO:0051775 - response to redox state [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="redox-sensing transcriptional repressor Rex"
                     /protein_id="HFG9699345.1"
                     /translation="MLGNKNISMAVIRRLPKYHRYLGDLLDRDIQRISSKELSDIIGF
                     TASQIRQDLNNFGGFGQQGYGYNVEALHTEIGKILGLDRPYNAVLVGAGNLGQAIANY
                     AGFRKAGFEIKALFDANPRMIGLKIREFEVLDSDTLEDFIKNNNIDIAVLCIPKNGAQ
                     EVINRVVKAGIKGVWNFAPLDLEVPKGVIVENVNLTESLFTLSYLMKEGK"
     gene            5116..5655
                     /locus_tag="ACGI5H_003663"
     CDS             5116..5655
                     /locus_tag="ACGI5H_003663"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860658.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FmdE family protein"
                     /protein_id="HFG9699346.1"
                     /translation="MVFVEELWKKAIEFHGHECPGLAIGFKAALAAREYLGCKQSGDE
                     EIVCISENDACGIDGIQVVLSCTMGKGNLLLRMTGKSVYHFFNRENGKSIRIYVKSKP
                     FQMDREGYKKYLLESDFEEIFEITDTKLRLPEKARIFKSLKCEVCGEFASEQYIRIEE
                     GKKVCLDCFNKYERFYEEY"
     gene            complement(5831..6001)
                     /locus_tag="ACGI5H_003664"
     CDS             complement(5831..6001)
                     /locus_tag="ACGI5H_003664"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888017.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF362 domain-containing protein"
                     /protein_id="HFG9699347.1"
                     /translation="MAYKITDACISCGACEAECPVSCISAGDDAYVIDAGSCIDCGSC
                     AGACPVDAPQPE"
     gene            6286..7353
                     /locus_tag="ACGI5H_003665"
     CDS             6286..7353
                     /locus_tag="ACGI5H_003665"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729218.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CapA family protein"
                     /protein_id="HFG9699348.1"
                     /translation="MKNKLVYICIMSLLLFVVGCSNNPNKESTIKKDSKNNQSQVKEE
                     KREPVKKDITISFAGDVTMGNYKGSSYYGSFDHEFKRQGEDYNYFLKNVKPVFEKDDL
                     TVVNLEGPLTTASNAKEKKFAFKGKPGYVNILKSGSVEAVSIANNHSEDYFEEGMKDT
                     QFILDENKINYFGLGKDAVVDVKGIKVGLLGYNGLSTEYNEKNLKQMEDDIKSLKKKS
                     DVVVVYFHWGIELDYYPDKKQKDFAHYAIDKGADLVMGSHPHVIQGIEKYKNKYIAYS
                     LGNFCFGGNKNPSDTDSYIYQQTFTFSDNKLTSIKEPNIIPTSITSSNSRNNYQPKIL
                     DGSEKDRVLNKLEKISKDLNK"
BASE COUNT         2797 a          972 c         1062 g         2538 t
ORIGIN      
        1 atgaatttgt caagtttaat ttagttgtaa ttttatcttt tattaaaaat aatataaatt
       61 aaaacatata aataaaatat tttatacaat atattgtaaa ggaggtaact ttgatgaaag
      121 cagaaaaaac aagtatatat ccaattatta aaaataattt aaacaaaata tcaattgttg
      181 aatataaaaa gggtcaaaga tttgtagcat cagataaaga cttacaagaa gtgttcttta
      241 taatagaggg agttgcatta gtggagtgta ctactagagg aggaaataaa tttcttgttg
      301 acattgtacc tgaaaatgaa tttataggca aaattagtta catatatgaa cataatttga
      361 aatgtgatat atttgcaaag accaatataa aattatttcg atttgaaaaa aatgtatttg
      421 aagagtttta tctcaaacca gattttattg cactatttca cagaaaatgt acaagaagaa
      481 tatatgaatt atataaaacc agaatggtaa gagaactatt ttcttgcaca gaagttattg
      541 cctattgtat atcaaataaa caagaaaata atgtctgcaa tataaaagct attcgtaatt
      601 tcagtgaaat ctattcaatt agtagaaaaa gtagatacca ttctctgcta aagttaactg
      661 aaaaggagat agtaaaaaaa atgggtaata catatgaaat tttaaactat gatgaattac
      721 ataaattggc atttgaagta aaagaatttt tggaagatga gtaaaaattg ttacttaatc
      781 aaaataaagt ataataattt ctgtaaaaaa tagaaatagt ctcactgaaa atcaaaaata
      841 ctttagttat tttcaatgag actgtttaga aatattgtat acttataatg tatagtataa
      901 ttattaatca atttccttta ctatattaat agcccatttt ttagataatg ctctaggaac
      961 accaaatata aacttaacca cttcttcact ataagtgagc aaaacgagta caaatatagg
     1021 tgcaccttta aatgcagcta taaaagttag aggaatagaa gctaaccaca tacatcctaa
     1081 ttctaaaaat agagcatatt tagtatctcc tccacttctt aaaataccaa ttataaccaa
     1141 tgtattaaaa gatttaagag ccattagtat tcccattata aagaatatct tagttatatc
     1201 agaagctaag ctatcagaaa cactaaacat ttttaataat aatggtatat ttaaaattaa
     1261 aataattcca agtattaaac cagctgaaaa tacaagtata gaaaactttt tagcatattc
     1321 aatggctctt ttaatatggt cagctccaag ttcatttcca agcataatag atgcaccaga
     1381 tgcaatacat acagctgtca ttatgaagaa attacctgta ctggttgcta tctggctagc
     1441 tgctatagca gaagtaccag ctcttgcata tgcaacagaa tacaggacag ttccaattgc
     1501 ccatacagag tcatttacaa atataggaaa gctttttgat gaaaaagatt ttataaaaat
     1561 tttatcaata gcttttagat tttttagacc aaactttaat atatagtctt ttttataaag
     1621 gtaaacataa gtaatcatta aaattaattc acatattcta gcaataacag tagctagagc
     1681 agcacctttt acacccaatg caggaagacc gaagttacca aatataaatc cataatttaa
     1741 aataacattt gttacaagtg caaatgcact acaaatcata cctaacttag gatttctaac
     1801 acctcttgaa ccagtgctaa atacagtact tacagcaatt aatggataac taaatactgc
     1861 aatactaaag taatctatac aaagttttac cacctcagaa tcatacgaaa atatgtgtat
     1921 aattggcttt ggtgttagta aagcaggaat aacaaataca aaacttaaaa caattgccaa
     1981 tacacaagta agacctgtga cttttcttat attactcaca tccttctttc cataaaactg
     2041 tgaaataaaa actccagcac ctcctgtgat accagataag gacatattaa aaagaaagaa
     2101 aaattggttt gcaactccaa ctgaagctac agatgtttcc cccaaactac ttatcataat
     2161 tgtatctatt acatttacag aagtagaaat taagttctgt atgataatag gtatacataa
     2221 agatagaagt attttataaa atcttttatt ttcgtctttt aaagaaaata gttcttgcaa
     2281 ataatcctct cctttttaca taaattcttc ccactcatca tatagagagg caaggttatt
     2341 ttctaaatta attttttctt ggctaacttc tttagcttta tctggattag agtatacttc
     2401 ttcttgacat aaaagtatat ctaatttttc aatttcaatc tctaactttt caatttcttt
     2461 ttctatattt tgtcttttta ttctattttt cttttctatt tctctttgtt ctctctcttt
     2521 tcttttttca tcttttattt gagttctagt tttttcttct ttttcttcta taatactcat
     2581 ctcttggatt tgcctttttt tatctatata ataatcataa tttcccagat attcagtaat
     2641 tccattttca tctaaaacta aaattttatc aacaacagta tttagaaagt atctatcatg
     2701 tgatattgta aatatagtcc catcataatt agttaatgcc tcttcaagga cttccttaga
     2761 atcaatatct aggtgattag taggctcatc taataacaat aagtttgcat ttgatagtat
     2821 aagtttaagt atggcaactc tagctctttc tccaccactc aatgtagaaa tcttcttaaa
     2881 aacttcttca tctacaaata aaaatgcccc taacatattt ctcaaagtag tttgagtaag
     2941 atgagtatta ttttcccaaa tctcatcaat tattgtgtta tctaaattaa gagttttttg
     3001 ttcctgatgg aagtaggaaa catgtacatt agttccaaat ttaatattgc cactaagagg
     3061 ttgtagttca ttagttatta ttttaaataa tgtagatttg ccaacaccat ttgcacctat
     3121 aagtgcaact ttttcccctc tatatatatc taaatccaag tctttaaaaa gtattctttc
     3181 tccataaccc atagatacat ctctaatttg aagaacatca ttaccactct ggacagaagg
     3241 cgtaaattgt atacgagctt ttttcctata agcttctggt ttatctaaaa cgtctacctt
     3301 gtctaatgct ttttctttac ttcttgcacg ctttaggtgt ttttctctac cataagcttt
     3361 tagtctttca attgattctt cttgcttttt tatttctttt tgttggtctt caaatttctt
     3421 aagctctagt tctttttcta ttttagataa ctcaacaaat ttagagtagt taccattata
     3481 tactttaagt tttttgttgt gaacttcaaa aattctattt acggattggt ctaagaaata
     3541 tctatcatga gatattaaca tgacagtccc tttatattgt tttaaaaata cttctaacca
     3601 ttctattgct tcagagtcta agtggttagt aggttcatca agtaacaata gagttggttt
     3661 cttaagaagt aattttccta aaagaactct agttttttca ccaccagaaa gtatgcttat
     3721 tggcttatcc atatcattgt cactaaatcc taatcccttt agaactcctt tggcttcaga
     3781 tttatatcca tatccattta aatctgaaaa taattctagt ttatgtgaat attcatccat
     3841 gattttttct ataattggag agtttgtttt tgtactttct tcagatattt taacctccaa
     3901 ttctcttaaa taggattcca tttctatcaa atttttaaaa acttctagta cttcttccaa
     3961 aatagtatta tccgaataaa aattggtatt ttgttctaaa tatccgattt cacaatcttt
     4021 agaagtgtaa atatctccac tatcatatcc ataaattcct gaaattattt taaataaagt
     4081 agtttttcca gtaccattaa caccgattat accaatttta tcgccttcat ttactgtaaa
     4141 actaatattt tctaatatag aatctatacc aaaactttta tttaagttat tacatgacaa
     4201 aacaatcata aatttctacc tccttgaact atctaaaatt ataatgtttt gatataatat
     4261 aatcaaggtt atatgtatta gttttgaaaa agaaatattt tattgtgaat caaacaaaaa
     4321 agaggacact tttaggaggt gaagatgttg ggaaataaaa atatatcaat ggcagttata
     4381 agaaggctcc caaaatatca tagatatctt ggagacttat tagataggga tatacaaaga
     4441 atatcttcta aagaattgag tgatataata gggtttaccg cttctcaaat aagacaagat
     4501 ttaaacaact ttggtggatt tggacaacaa ggatatggtt ataatgtaga agctcttcat
     4561 actgagatag gtaaaattct tgggttggat cgaccataca acgcagttct tgtaggagca
     4621 ggtaacttag gacaagctat agccaattat gcaggattta gaaaagctgg attcgagata
     4681 aaagctttat ttgatgcaaa tcctagaatg ataggtttaa agataagaga gtttgaagta
     4741 ttagattcag atactttaga agactttata aaaaacaata atatagatat tgctgtatta
     4801 tgtataccta aaaatggagc acaagaagtt attaatagag ttgtaaaagc tggaatcaaa
     4861 ggtgtatgga attttgcacc tttagattta gaagttccga aaggtgttat agttgaaaat
     4921 gtaaacttaa cagaaagttt atttacctta tcgtatttaa tgaaagaagg aaagtagaca
     4981 acttaaacat attaataatg agcagttgtg aagagtattg agaaagtcag aagatttaat
     5041 attaaatcct ctggcttttt gaaatattag gataaaaatt taaataatgt atggaaataa
     5101 acaatattaa ggagagtggt ttttgtggag gaattatgga aaaaggcaat tgaatttcat
     5161 ggtcatgaat gtccagggtt agctatagga tttaaagcag cacttgcagc aagagaatat
     5221 ttaggatgta aacagtcagg agatgaggaa attgtatgta tttctgaaaa tgatgcttgt
     5281 ggaatagatg gtatacaagt cgtgctaagt tgcacaatgg gtaaaggaaa tttactactt
     5341 aggatgactg ggaaatcagt atatcatttc tttaataggg aaaatggaaa atctataaga
     5401 atatatgtaa agtcaaagcc atttcaaatg gatagagaag gatacaaaaa gtacttatta
     5461 gaaagtgatt ttgaagaaat atttgagatt acagatacta agttaagact tcctgaaaaa
     5521 gcaagaatat ttaaatctct taaatgtgaa gtgtgtggtg aatttgcatc tgagcaatat
     5581 ataaggattg aagaaggaaa gaaagtatgt cttgattgct ttaataaata tgaaagattt
     5641 tatgaggagt attaaaatta taaattagat taaagttaaa agtattagat atgtgctaac
     5701 agtattttaa gatgaattag gtagcaacat aataaagtat ataaataata ttaattgaat
     5761 catacataat taaaaagagg ctgattagta tttataaaat aaaatcagtc tctttatgaa
     5821 taacgaatta ttattctggt tgaggtgcat ctacaggaca agctcctgca caagaaccac
     5881 agtctataca agaaccagca tctataacat atgcgtcgtc tccagctgat atacagctaa
     5941 cagggcattc agcctcacaa gcaccacagc ttatacaagc gtcagtaatt ttatatgcca
     6001 ttttgaaatc ctccctttta tatgtattgt aattcaataa cattataaca aatattattg
     6061 aatataacaa ttaaattaat tctacaacaa aaactttatt atgatattct tgttttaaag
     6121 ttttacaata aagtttaatc tgcttatatt tttatttatt ttaaagaagt ttattttaaa
     6181 aataaaatta aatttaaaaa gttatgtatt gattatattt aaaaatgtta tactctaaaa
     6241 aagtatattt tatttaaaaa tttattaata caaaggagat ttactatgaa aaataaatta
     6301 gtttacatat gtattatgag tctattgcta tttgtagtag gatgttctaa taatccaaat
     6361 aaggaaagta ccattaaaaa agactctaag aataaccaaa gccaagttaa agaagaaaaa
     6421 agagaacctg tgaaaaaaga tataactata agtttcgctg gtgatgtaac tatggggaac
     6481 tataaaggtt catcatatta tggcagtttt gaccatgaat ttaaaagaca aggagaagat
     6541 tacaattatt ttcttaaaaa tgtaaaacct gtatttgaaa aagatgactt aacagtggtt
     6601 aatttagaag gtccacttac tacagcgtca aatgcaaaag aaaaaaaatt tgcatttaaa
     6661 ggaaagcctg gatatgtaaa tattttaaaa tctggaagtg tagaggcagt aagtattgca
     6721 aataatcatt cagaagatta ttttgaagaa ggaatgaaag atacacagtt tatattggac
     6781 gagaataaaa taaattattt tggattaggg aaagatgctg ttgtagatgt caaaggaatt
     6841 aaagtgggtc tattagggta taatggatta tcaactgaat ataatgaaaa aaatttaaaa
     6901 caaatggaag atgatattaa gtccttaaaa aagaaatcgg atgttgttgt agtgtacttt
     6961 cattggggga tagaattaga ttattatcca gataaaaaac aaaaagattt tgctcattat
     7021 gctatagaca agggagcaga tttagttatg gggtctcacc cacatgtgat tcaaggaata
     7081 gaaaagtata aaaataagta tatagcttat agtctaggga atttttgctt tggaggaaat
     7141 aagaatcctt ctgatacaga tagttatata tatcaacaaa cctttacttt ttcagataat
     7201 aaattaactt caattaaaga gccaaatata ataccaactt caataacatc tagtaactcc
     7261 agaaataatt atcaaccaaa aatattggat ggaagtgaga aggatagagt tttaaataaa
     7321 cttgaaaaaa taagcaaaga tttaaataaa taaaatgtaa aaaaaaata
//
LOCUS       DAYAOO010000138         7314 bp    DNA     linear   BCT 12-OCT-2024
DEFINITION  TPA_asm: Clostridioides difficile isolate ST8-SSI-h139-18
            SAMN40601845-rid21577343.denovo.142, whole genome shotgun sequence.
ACCESSION   DAYAOO010000138 DAYAOO010000000
VERSION     DAYAOO010000138.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN40601845
            Sequence Read Archive: SRR28438827
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 7314)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7314)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-MAY-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-MAY-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002157583.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002157583.1
            Genome Coverage       :: 163x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/11/2024 16:19:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 4,038
            CDSs (total)                      :: 3,963
            Genes (coding)                    :: 3,930
            CDSs (with protein)               :: 3,930
            Genes (RNA)                       :: 75
            rRNAs                             :: 6, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 60
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 33
            CDSs (without protein)            :: 33
            Pseudo Genes (ambiguous residues) :: 0 of 33
            Pseudo Genes (frameshifted)       :: 7 of 33
            Pseudo Genes (incomplete)         :: 25 of 33
            Pseudo Genes (internal stop)      :: 11 of 33
            Pseudo Genes (multiple problems)  :: 8 of 33
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7314
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN40601845-rid21577343.denovo.142"
                     /isolate="ST8-SSI-h139-18"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Denmark"
                     /collection_date="2018"
                     /collected_by="Statens Serum Institute"
     gene            complement(<1..942)
                     /locus_tag="ACGI5H_003666"
     CDS             complement(<1..942)
                     /locus_tag="ACGI5H_003666"
                     /EC_number="5.4.99.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003431188.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0009982 - pseudouridine synthase activity
                     [Evidence IEA];
                     GO_process: GO:0001522 - pseudouridine synthesis [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="RluA family pseudouridine synthase"
                     /protein_id="HFG9699349.1"
                     /translation="MFYFLKVKVGDIMDEVKEFLVLEEEEEVRLDIYLAEQLGDMSRS
                     YIQKIIKDGKVKVNNKVEKARYLVKEEDNIVIEIPEPKVLEVLPQDIPIDIVYEDDDV
                     LIINKPQDMVVHPAPGNYENTLVNGILYHCKDKLSSINGVIRPGIVHRIDKDTSGLLM
                     IAKNNYAHNFLAEQLKEHTITREYEFICYGVVKEDKITVDKPIGRNPKDRLKMAVVKD
                     GKNAITHFEVVERFDKFTHMRARLETGRTHQIRVHALSINHPLLGDYVYGPKETKFKL
                     KGQTLHAKKLGFIHPTTKEYIEFNSELPEYFKEVIKKI"
     gene            complement(911..1357)
                     /gene="lspA"
                     /locus_tag="ACGI5H_003667"
     CDS             complement(911..1357)
                     /gene="lspA"
                     /locus_tag="ACGI5H_003667"
                     /EC_number="3.4.23.36"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729400.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_function: GO:0004190 - aspartic-type endopeptidase
                     activity [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA];
                     GO_process: GO:0009306 - protein secretion [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="signal peptidase II"
                     /protein_id="HFG9699350.1"
                     /translation="MLYILIIILLIGLDQLSKIWVLNNLVDVSTIPIINNVFHLTYVE
                     NRGAAFGLLQNNQWIFIIVALLATVFGLYYLNTRKVHIFGRLGIILIISGALGNLVDR
                     VRLGFVVDYFDFRVIWEYVFNVADVFVVVGTVFLCIYVLFFESKSR"
     gene            complement(1667..2446)
                     /locus_tag="ACGI5H_003668"
     CDS             complement(1667..2446)
                     /locus_tag="ACGI5H_003668"
                     /EC_number="3.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416201.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide deacetylase family protein"
                     /protein_id="HFG9699351.1"
                     /translation="MKKIICGICICLLSIVGVYTYNHNTHNQDSSKEAYSLNDNIKDD
                     YEDVIIKKGNEDEKILALTFDDGPDEDFTPQVLDILKKNDVKATFFVVGEKVEYNKEL
                     LKRQYDEGHEIGNHTFTHINVAKNSYSSVEKEITDTQNIIKSVIGVEPKIFRPPYRAM
                     SKSVCDIIVSKGMNIILWSNLDPRDWSNPGVDAIINTILTKVQNGNIILLHDYNTKRN
                     DKSQTIQALEVVIPKLKERGYKFVTVSELIQHLDKNKQVQK"
     gene            complement(2501..2983)
                     /locus_tag="ACGI5H_003669"
     CDS             complement(2501..2983)
                     /locus_tag="ACGI5H_003669"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729402.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TraR/DksA C4-type zinc finger protein"
                     /protein_id="HFG9699352.1"
                     /translation="MDTKKYKDKLLKERENLTNLVEDMKDNTLFGDTTKHTSEKYSSG
                     ELSSYDNHIGDMGTDLYMQNMQNSLINHEEGRLYQIDLALSKIENGTYGICDLCHNQI
                     DLERLDILPDTSLCNDCAKKENNLLGDAMQNPDVEDSNFYSEDLTNLTDLNKNGILRD
                     "
     gene            complement(3249..4670)
                     /locus_tag="ACGI5H_003670"
     CDS             complement(3249..4670)
                     /locus_tag="ACGI5H_003670"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454919.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbon starvation protein A"
                     /protein_id="HFG9699353.1"
                     /translation="MVSFLGSIVVLIVGYFVYGTFVEKVFGTNDKNQTPAIACRDGVD
                     YVPMKWKRIFLIQFLNIAGLGPIFGAIQGALFGPSAFLWIVFGTIFAGGVHDFASGYL
                     SMKNKGTSASELVGLYLGNGAKIAMRIFSVILLVLVGVVFVTGPAGLLKTLTGVNAQI
                     WVGVIILYYIMATVLPIDKLIGKIYPLFGAALLIMAVGVAGGLIIKGYNIPNINLQNM
                     NPNGTPLFPYLFITIACGAISGFHATQSPLMARCVEKESEARPVFYGSMVAEGIIALV
                     WAAAAMSYFHGIPQLNVIFNDGGAATVVNTVSVGLMGPIGGALAILGVVACPITSGDT
                     AFRSARLTIADAMNYNQDAVKNRFLIALPLFAVGVALTFIDFNIIWRYFSWANQTLAM
                     IMLWTGSAYLVKANKNHYITTLPALFMTVVTFSYIMQAKEGFRLPVNISNGIGVIVAI
                     ILGLLFFKKAKHIKEQNNHKLAS"
     gene            complement(4816..4995)
                     /locus_tag="ACGI5H_003671"
                     /pseudo
     CDS             complement(4816..4995)
                     /locus_tag="ACGI5H_003671"
                     /inference="COORDINATES: protein motif:HMM:NF016296.4"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="LytTR family DNA-binding domain-containing
                     protein"
     gene            complement(5008..5586)
                     /locus_tag="ACGI5H_003672"
     CDS             complement(5008..5586)
                     /locus_tag="ACGI5H_003672"
                     /inference="COORDINATES: protein motif:HMM:NF012301.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HFG9699354.1"
                     /translation="MRAIIVEDEFPARKELRYFIENKSGIEVVSEFTNGIEVLDFIQE
                     NKIDVIFLDINIPHLDGMLLAKTLNQFKSRPKIVFITAYESYAVDAFSLDVFDYILKP
                     YSEERIISMLNKLEKSEMSDIELFNVNSNLYKYKKEAVNQEIEEITHKISLWKGDKLV
                     VIDIDDIYYCEANERQTFIYTEKEKFILKEGI"
     gene            complement(5591..6793)
                     /locus_tag="ACGI5H_003673"
     CDS             complement(5591..6793)
                     /locus_tag="ACGI5H_003673"
                     /EC_number="2.7.13.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426902.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000155 - phosphorelay sensor kinase
                     activity [Evidence IEA];
                     GO_function: GO:0004673 - protein histidine kinase
                     activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0007165 - signal transduction [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HFG9699355.1"
                     /translation="MKTSILIALIEKTSLIVVLFLLITKLKIFKQIFQKEEYSFNDLV
                     CIALVFTFLAIFGTYSGINYMGSIVNTRIISIVSGGILFGPMVGITAGVFSGIHRYFM
                     DIGGITSVPCLLSSILAGVLSGFLYKRIPKQHRVMYGILVGMISESFTILLIYLISYP
                     HSLAIQIIGGIYLPLIVGQIGIGFVISIVEGIEKDKKDIEARNKAEIKALQRQINPHF
                     LFNSLNTIASFIRFSPDKARELIINLSTYLRYNLEYSDNLIDINKEIEQVKSFVEIEK
                     ARFGELLTVSYDIEDVNIKIPSLIIQPLVENAIIHGILESGRAGVVKISIKKLPYSLE
                     NTVRISIEDNGIGISEEIINNVYQDNMPENKIGLYNVHLRLKLMYGRGLNIRRIDNGT
                     LIVFYVKE"
BASE COUNT         2432 a         1280 c          710 g         2892 t
ORIGIN      
        1 tatcttttta ataacttcct taaaatactc aggtaattct gaattaaatt cgatatattc
       61 cttagtagta ggatgtataa atcccaactt cttagcgtgc aaagtttgtc cttttaattt
      121 aaatttagtt tcttttggac catatacata atcacctaaa agtgggtgat ttatagacaa
      181 agcatgaact cttatttgat gagttctacc agtttcaagc ctagctctca tatgtgtaaa
      241 cttatcaaat ctttctacaa cttcaaagtg agtgattgca ttttttccat cttttactac
      301 agccattttt aatctatcct taggatttct ccctataggt ttatcaacag ttattttatc
      361 ttctttaacc acaccatagc atataaattc atactcccta gttatagtat gttcctttaa
      421 ctgttctgct agaaaattat gtgcataatt gttcttagct atcataagaa gaccagaagt
      481 atctttgtct attctatgaa ctataccagg tctaataact ccatttattg atgacaactt
      541 atctttacaa tgatataaaa tcccatttac taacgtattt tcatagtttc caggagcagg
      601 atggacaacc atatcctgag gtttatttat tattaagaca tcatcatctt catatacaat
      661 atctattgga atatcttgag gtaaaacttc taatacttta ggttctggta tctctataac
      721 aatattatct tcctctttaa ccagatatct agctttttct actttattat taacctttac
      781 ttttccatct tttataattt tttgtatata acttcttgac atatcaccta attgttctgc
      841 tagataaata tcaagtctaa cttcttcttc ctcttcaagt actaaaaact cttttacttc
      901 atccattata tcacctactt ttactttcaa aaaataaaac atatatacat aaaaacacag
      961 ttcctacaac tacaaataca tcagctacat tgaatacata ttcccatata actctaaagt
     1021 cgaagtaatc taccacaaaa cctaatcgta ctctatcaac tagatttccc aatgcaccag
     1081 atataattaa tataattccc aaccttccaa atatatgtac tttccttgta ttaagatagt
     1141 ataatccaaa taccgttgca agtaatgcaa caattataaa tatccattga ttattttgta
     1201 ataatccaaa tgctgcacct ctattttcga cataagttaa atgaaataca ttatttatta
     1261 ttggtattgt tgatacatcc accaaattat tcaataccca tattttagac agttggtcta
     1321 aacctatgag tagaattatt attaatatat atagcaatga tttttccccc tataaattat
     1381 ttaaaaacca attttatttg aagcacacta ttattattat acaaaaaaaa tgctctaaag
     1441 agcaacttta ttaaaattgt attttcttaa taaagctaga acaaaattta aaatagtact
     1501 acttttttta tattgtagat ttctacatat ttaaaatcat atcattatgt ataaaaaatt
     1561 taaaaatacc atactaatca atattttttg tgtattttat agattaaaga ttaatgatgt
     1621 ctgtaattta aacttacaat caccactaat cttcaaacaa atatttttac ttttgcactt
     1681 gcttattttt atctaaatgt tgtataagtt cagatactgt tacgaattta tatcctctct
     1741 cttttaattt aggaattact acttctaaag cttgtatagt ttgtgattta tcatttcttt
     1801 tagtgttata atcatgtaaa agtattatat taccattttg gacctttgta aggatagtat
     1861 ttataattgc atctactcca gggttagacc aatctctagg gtctaagttt gaccaaagaa
     1921 ttatattcat tcctttagaa actataatat cacagacact tttactcatg gctctatatg
     1981 gaggtctaaa tatctttggt tctactccta tcacactttt tataatattt tgcgtatctg
     2041 ttatttcttt ttcaacacta ctataactat tttttgcaac atttatatgt gtaaatgtat
     2101 gattccctat ttcatgcccc tcatcatatt gtctttttaa taattctttg ttatattcta
     2161 ctttttctcc aactacaaaa aaagttgctt ttacatcatt tttctttaat atatcaagta
     2221 cttgtggtgt aaaatcctca tctggaccat catcaaaagt caatgctaaa attttttcat
     2281 cctcatttcc tttttttatt attacatctt cataatcgtc ttttatattg tcatttaaac
     2341 tatatgcttc ttttgaacta tcttgattat gtgtattatg attatatgta tatacaccta
     2401 ctatagataa taaacatata catataccac atattatttt cttcatgtca ttacctcttt
     2461 tctaattcat tctagcaata tattttataa tgtcagtttt ttaatctctc aatattccat
     2521 ttttatttaa atcagttaaa tttgttaggt cttctgaata aaagttagaa tcttctacat
     2581 cagggttttg cattgcatca cctaataaat tattttcctt ctttgcacaa tcattacata
     2641 aacttgtatc tggcaatata tccaatcttt ctaaatctat ttgattatga cataaatcac
     2701 aaatcccata tgttccattc tctattttag ataatgctaa gtctatttga tacaatcttc
     2761 cctcttcatg atttattaga ctgttttgca tattttgcat atataaatct gttcccatgt
     2821 ctcctatatg attatcataa ctagataatt ctcctgatga atacttttca cttgtatgtt
     2881 tagttgtatc tccaaataaa gtattatctt tcatatcctc tactaaatta gttaaatttt
     2941 ctctttcttt caataattta tctttatatt ttttagtatc catttttaac acctctaatt
     3001 ttaatattta catcataaaa atagtatgtg gaaaagtaaa ttaaacatac aataaaaata
     3061 agatttgatt cgaaaaatgg aatgtctcaa aatgaaattt ttagttcatt taaccctctt
     3121 ttttatatga aatcaaatat atttttatcc tttcagcaat aaaaaagaga cttatctcta
     3181 ttttgagata gtctcttctt tgaacataat ttaaatacaa ttttttaatt tttatagtta
     3241 ttattttact aacttgccaa tttatgatta ttttgttctt taatatgttt tgctttttta
     3301 aagaataaaa gaccaagaat tattgctaca ataacaccta ttccattaga tatattaact
     3361 ggtagtctaa atccttcttt tgcttgcatt atataactaa atgttactac agtcataaaa
     3421 agtgctggta atgtagttat ataatggttt ttatttgctt tgactaaata tgcagaacca
     3481 gtccacaaca ttatcattgc aagtgtttga tttgcccaag agaaatatct ccaaattata
     3541 ttaaaatcta taaatgtaag agcaacacca actgcgaata atggtaaagc tattaaaaat
     3601 ctatttttga ctgcatcttg attataattc attgcatctg ctattgtcag cctagcactt
     3661 ctaaatgctg tatctccaga agttatagga catgccacaa ctccaagtat agctaaagct
     3721 cctccaatag gccccattaa tccaacagat actgtattta ctactgttgc tgctccacca
     3781 tcattaaata tcacattaag ttgaggtatg ccatggaaat atgacatggc tgctgctgcc
     3841 caaactaaag ctattatacc ttctgcaacc attgacccat aaaatactgg tcttgcctca
     3901 ctctctttct caacacatct cgccataagt ggtgattgag ttgcatgaaa acctgatatt
     3961 gctccacatg ctattgttat aaataagtat gggaataaag gtgttccatt tggattcata
     4021 ttttgtaaat ttatatttgg tatgttatac ccctttatta ttaatcctcc agctacacct
     4081 actgccataa ttaataatgc tgctccaaat aaaggatata ttttaccaat caatttatct
     4141 attggtaaaa cagtagccat aatataataa agtattatca ctccaaccca tatttgtgcg
     4201 tttacacctg tcaatgtctt taataatcct gctggacctg ttacaaatac aactccaacc
     4261 aatactaaaa gaataacact aaatattctc attgctattt ttgcaccatt tcctagataa
     4321 aggcctacca actctgatgc agatgtacct ttgtttttca ttgatagata tcctgaagca
     4381 aaatcgtgta ctccaccagc aaagattgtt ccaaacacaa tccataaaaa tgctgatggt
     4441 ccaaataatg ctccttgtat agctccaaat atcggaccta accctgctat atttagaaac
     4501 tgaattaaaa agattctctt ccatttcatt ggcacataat ctactccatc cctacaagct
     4561 atagctggag tttgattttt gtcattggtt ccaaaaacct tttctacaaa agtaccatag
     4621 acaaaataac ctactataag tactactatt gaacctaaaa agcttaccat aaattcatcc
     4681 ccttagtttt tatataattg ctttataaat ttttatgagt ttaagaaaac tatttccagt
     4741 tcaaatagta atactttttt atgctaatat aaatattaat tacattaagt gcatatttaa
     4801 gtacatgaaa tgactttata tatgcattaa cagcctaaat tcttttactt tgcttctact
     4861 tacagttact tcataatcac tattttttaa ttttaatatg tatgtattat taaaccatgg
     4921 tataatttct tttactttgg ttaagtttac gatataagac ctatgtgttc taaaaaatgt
     4981 tttatcattt ataagatttt cgacttctta tatgccttct tttaatataa acttttcttt
     5041 ctcagtatat ataaatgtct gcctttcatt agcttcacag taatatatat catcaatatc
     5101 tattacaact aatttatcac ctttccaaag gctaatttta tgtgttattt cttctatctc
     5161 ctgatttact gcttccttct tatatttgta taaattacta tttacattaa atagttcaat
     5221 atcactcatc tcactttttt ctaatttatt cagcatagaa ataattctct cttcagaata
     5281 tggtttcaat atataatcaa atacatccaa agaaaaagca tctactgcat aactttcata
     5341 tgctgttata aaaacaattt taggtcttga tttaaactga tttaatgttt ttgcaagtag
     5401 cattccatca agatgaggta tatttatatc taaaaaaatt acatctattt tattttcctg
     5461 aataaagtct aacacctcta taccattggt aaattcactt actacctcga ttccactttt
     5521 attttcaata aaatatctca attcctttct tgctggaaat tcatcttcca ctattatagc
     5581 tctcatactt ctactccttt acataaaata ctatcaaagt cccattatct attcttctta
     5641 tattaagccc tcttccatac atcagtttaa gccttaaatg tacattataa agcccaatct
     5701 tattttctgg catattatct tgatatacat tatttataat ttcctcactt atacctatac
     5761 cattatcctc tattgatatt ctcacagtat tttctaatga atacggtaac ttttttatgg
     5821 atattttcac tacaccagct ctaccacttt ctaaaatacc atgtattatt gcattttcca
     5881 ctaatggttg tataatcaaa cttggaatct ttatatttac atcttctata tcataagata
     5941 cagttagtaa ttctccaaac ctagcttttt ctatctctac aaaagattta acttgttcaa
     6001 tctctttatt tatatcaatt aagttatcac tatattcaag attatatctt agataagttg
     6061 ataaatttat tattaactct ctagccttat ctggactaaa tcttataaat gaagctattg
     6121 tgtttaggga attaaacaaa aaatgtggat taatttgtct ttgaagtgct tttatttctg
     6181 ctttatttct cgcttctata tcttttttat ctttctcaat cccctctact atagatataa
     6241 caaatcctat tccaatctgc ccaactatta aaggtaaata tattccaccg attatttgaa
     6301 ttgctaaaga atgtggatat gatattaagt atataagtaa tatagtaaaa ctttcagaaa
     6361 tcatgcctac caatattcca tacattactc tatgttgttt tggtatcctc ttatatagaa
     6421 atcctgataa tacacctgct agtatacttg ataaaagaca tggaacagat gttatccccc
     6481 caatatccat aaaatatcta tgaatccctg aaaaaactcc tgctgtaata cctaccatcg
     6541 gaccaaataa aatgccacct gatactatag atattattct agtgtttact attgacccca
     6601 tataatttat accactataa gttccaaata tggctaaaaa agtaaaaact aatgctatac
     6661 agaccaagtc attaaaacta tattcttcct tttgaaatat ctgcttaaat atttttaact
     6721 ttgttattag aagaaacaat actacaataa ggcttgtctt ttctattaat gcgattaaaa
     6781 ttgatgtttt cataatcccc ctttaaaaaa taaattttta cacactctaa atttattatg
     6841 gttgttataa attacatatt tgaagtaatc ctatcacaaa actttccaca tttaatcttt
     6901 taattaaata agaaatagtt gtacttctat taacaactaa tactagctag cataagcttg
     6961 taataacttg tagttattat taactttaca attctagtat ttaattttat actttagaaa
     7021 tctcttttct tagaaataat actttcgaat atcatataat acaatattat gtagattctt
     7081 actcatacaa catatttctt taaaaatttt atactattct ttgttcaaat atctcatttg
     7141 atttaattgt gttaaacaca cattatcatc tctctgttat atatttatta tatagccgta
     7201 tatcgataaa gtaaataaat cccatattta aaataatatg tttgacaata aattattata
     7261 atgtatattt accataataa tttgtcaacc ttgaaagtta cttctataat tatt
//
LOCUS       DAYAOO010000139         7254 bp    DNA     linear   BCT 12-OCT-2024
DEFINITION  TPA_asm: Clostridioides difficile isolate ST8-SSI-h139-18
            SAMN40601845-rid21577343.denovo.143, whole genome shotgun sequence.
ACCESSION   DAYAOO010000139 DAYAOO010000000
VERSION     DAYAOO010000139.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN40601845
            Sequence Read Archive: SRR28438827
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 7254)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7254)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-MAY-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-MAY-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002157583.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002157583.1
            Genome Coverage       :: 163x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/11/2024 16:19:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 4,038
            CDSs (total)                      :: 3,963
            Genes (coding)                    :: 3,930
            CDSs (with protein)               :: 3,930
            Genes (RNA)                       :: 75
            rRNAs                             :: 6, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 60
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 33
            CDSs (without protein)            :: 33
            Pseudo Genes (ambiguous residues) :: 0 of 33
            Pseudo Genes (frameshifted)       :: 7 of 33
            Pseudo Genes (incomplete)         :: 25 of 33
            Pseudo Genes (internal stop)      :: 11 of 33
            Pseudo Genes (multiple problems)  :: 8 of 33
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7254
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN40601845-rid21577343.denovo.143"
                     /isolate="ST8-SSI-h139-18"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Denmark"
                     /collection_date="2018"
                     /collected_by="Statens Serum Institute"
     gene            506..1846
                     /locus_tag="ACGI5H_003674"
     CDS             506..1846
                     /locus_tag="ACGI5H_003674"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888366.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GHKL domain-containing protein"
                     /protein_id="HFG9699356.1"
                     /translation="MIKSSLFWNIFIAISFMIEWFLCKKMLDYTSEKRISNKKINFCM
                     VGIIVFADIIYFFDVPPNIRVIISMIITIAFYKISYDVGFIKSVLISLIYWMLLIATD
                     ALSISLTVWLNSINDMSSMGTGDIYRIESIILGKILLIVSLLLYRALKIKLNIEINKR
                     TLFYIVIPIVANIASFFVIFEYIFNPGSGSLIHNFQFVMISVVLLISSITLVLIAKKL
                     QQYNTLVVENNMIKNTLKYENEYYEDIEKKYLKTRLLSHDMKNHILCINAMIKKGIDV
                     TSYLNNLQVEIQSNDLLFNTGNFILDAILSEKKEVCDKNDIELKIGINFSCCEAVELV
                     DICHIFSNILDNAIEACNKIDSGNRVICVKGDVMQNFYLIRVENTKINKIITKNGDIL
                     TDKKGSLHGLGIKSVKNSVNKYGGNVVIEYDDKKFVVKIAIPLRNVKKAVNHVI"
     gene            2320..4221
                     /gene="cooS"
                     /locus_tag="ACGI5H_003675"
     CDS             2320..4221
                     /gene="cooS"
                     /locus_tag="ACGI5H_003675"
                     /EC_number="1.2.7.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888019.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016151 - nickel cation binding [Evidence
                     IEA];
                     GO_function: GO:0043885 - anaerobic carbon-monoxide
                     dehydrogenase activity [Evidence IEA];
                     GO_function: GO:0051539 - 4 iron, 4 sulfur cluster binding
                     [Evidence IEA];
                     GO_process: GO:0006091 - generation of precursor
                     metabolites and energy [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="anaerobic carbon-monoxide dehydrogenase
                     catalytic subunit"
                     /protein_id="HFG9699357.1"
                     /translation="MACNTCKMCESADKKLESFVASKDVETAFHRTEDQKVKCGFGLQ
                     GVCCRLCSNGPCRVTPKSPRGICGADADTIVARNFLRAVASGAACYLHVVENTAKNLK
                     NVGITKGVVKGEKTLNQLAEMFGIESDEKYDKCIKVADKVINDLYKSRDDKMELVEKI
                     AYAPRVKKWKELGIMPGGAKSEVFDAIVKSSTNLNSDPVDMLVNCLNLGISTGLYGLT
                     LTNLLNDVMLGEPVIRMAPVGFNVIDPDYINIMITGHQHSTFANFQDRLKDEDVIKLA
                     QSVGAKGFKLVGCTCVGQDLQLRGEHYQEVFAGHAGNNFTSEAVLSTGAIDIVLSEFN
                     CTIPGLEPIADKYKVKMVCLDDVAKKANAEYIGLDRSKLDELSNTLIEKALESYKERR
                     GSIEIDIPKDHGFEQSLTGVSEKNLKAFLGDSWKPLINLIAEGKIKGVAAVVGCSNMT
                     AGGHDVNTVELTKELIKKDIIVLSAGCSTGGLENVGLMSPGAEELAGENLKEVCKTLG
                     IPPVLNFGPCLAIGRLEIVATELAAELGIDLPQLPLVLSAPQWLEEQALADGAFGLAL
                     GLPLHLALPPFITGGKLVTEVLTEKLKDLTGGHVIVNPDPKSSANQLEEIIIDRRKNL
                     GLKDVECNA"
     gene            4214..4687
                     /locus_tag="ACGI5H_003676"
     CDS             4214..4687
                     /locus_tag="ACGI5H_003676"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860659.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4Fe-4S dicluster domain-containing protein"
                     /protein_id="HFG9699358.1"
                     /translation="MHRIFINKDLCTGCKSCVLACMLKHNKDYDMYTLDLENIDNDSR
                     GHIELDSKHNNPVPILCRHCDEPECVLACMSGAMHKDSESGIVSYDEEKCGSCYMCVM
                     SCPYGLLKPDDRSKQNILKCDLCKDEEYPRCVANCPSGAIELQKEENDELCSVRG"
     gene            4662..5888
                     /locus_tag="ACGI5H_003677"
     CDS             4662..5888
                     /locus_tag="ACGI5H_003677"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895268.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-dependent oxidoreductase"
                     /protein_id="HFG9699359.1"
                     /translation="MNYVVLGASAAGINAVKTLRELDKDSNIVVISKDENVYSRCMLH
                     HVISEHRILKQINFVDEDFMEQNNVKWIAGKTVKGIDINKKVVQTEDITVNYDKLLIA
                     TGASSAIPPIKNLRDGNFVYSVRNIDDIYKIKEKAQNSKNVVIIGAGLVGIDALVGLF
                     KYEQLNISVAFMEKYILDRQLDEYTASVYENKFKEKGVKFYPSASIQEIVLDNSKNVT
                     GVAFSNGEVLDADMVIVATGVKPNADFLDGTGIEYDRGIIIDDMCQTTQKDIYAAGDV
                     VGKNAIWPLAVKQGIVAAYNMVGKDKKIEDEFAFKNSMNFMDIPTISIGMNTPVDDSY
                     KVLTRHGINDYKKFVFKDNVIYGAVIQGDISYVGVLTYLIKNKVEIYDLENRIFDICY
                     ADFFNIKENGEFCYSV"
     gene            complement(6027..7214)
                     /locus_tag="ACGI5H_003678"
     CDS             complement(6027..7214)
                     /locus_tag="ACGI5H_003678"
                     /EC_number="2.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018594563.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HFG9699360.1"
                     /translation="MNITKNFLKDYLEKFGETPFLVRLKDEEEFLIGEGSPQFKVIVN
                     NDISKSELLKSTSLALGEAYINRDIEVEGDLFLTLNLLLKQIDKFNIDNSAVKHLLHS
                     SNSMRHQKKEIHAHYDIGNDFYSLWLDKTLSYSCAYFRNDNDTLYDAQVNKVHHILTK
                     LNLEEGMSLLDIGCGWGFLLIEAAKKYKIHGVGITLSEEQFKEFNARIKEENLQDYLE
                     VRLMDYRELKKSDLMFDRIVSVGMLEHVGRENYELFIKNVNAVLKDGGLFLLHYISGL
                     QESYGDPWIKKYIFPGGVIPSLREMIHICSDYKYHTIDVESLRLHYVKTLLYWQKNFS
                     ENLPKIKEMFDDKFIRMWDLYLCSCAAAFNTGIIDIHQILFTKGIKNDLPLTREYMYN
                     CSK"
BASE COUNT         2768 a          768 c         1262 g         2456 t
ORIGIN      
        1 attatttact aataaatcta caatagaaat gcttttgttg taagaatcat tttatctaat
       61 gattgttttt tataatagtt aaatttccat ttgtagtgtt taaatataaa tctataacag
      121 catttctata aatgttataa atcactataa tgattcaact caaagttact gcttaaagaa
      181 gcagagattt tatcaaggta tatcatggaa aaaaatattt tattgtaata tttataagat
      241 tttattatag aaataatgta aaaactttat aaataatata ttttatacct agttatagat
      301 aaatttatat agttattatt aaaaaaagca ataaaaagtt taattcaatt tagcaaattt
      361 agtgatataa ttaaaaaaga aaagaaatat ggacttattt ggaataattt tgacaatcta
      421 tttactacat gtgtagagtc gtatataatt aaattataca taaaatataa aaaaataatt
      481 tagtaatacg ttaggagaaa gtattatgat aaagtcaagc ttattttgga atattttcat
      541 tgcgatatcc tttatgatag aatggtttct ttgtaagaaa atgctagatt atacaagtga
      601 gaaaaggatt tctaacaaaa aaataaactt ttgtatggta ggtattattg tttttgctga
      661 cataatatat ttttttgatg tacctccaaa tataagagta attatatcta tgataattac
      721 tattgcattt tataaaatct catatgatgt ggggtttata aagtctgtat taatatcctt
      781 aatttattgg atgttactaa tcgccacaga tgctttgagt atatctttaa cagtttggct
      841 taattctata aatgacatga gtagtatggg gacgggagat atatacagaa ttgagtctat
      901 aatattggga aagatacttt tgattgtgtc tttgctttta tatagagcct taaagataaa
      961 acttaatata gaaataaata aaaggacatt attttatata gttattccta tagtcgctaa
     1021 tatagcatct ttttttgtaa tttttgaata catatttaat ccagggtctg gtagcttaat
     1081 acataatttc caattcgtta tgatttctgt tgtattgctt atatcaagta tcactttagt
     1141 tttaattgct aaaaaattac agcaatataa tactttagtt gtagaaaaca atatgattaa
     1201 aaatactttg aagtatgaaa atgagtatta tgaagatata gaaaagaaat atttaaaaac
     1261 tagattacta agtcatgata tgaaaaatca catattgtgt ataaatgcta tgattaaaaa
     1321 aggtattgat gttacttctt atttaaataa tttgcaggta gaaattcaga gtaatgactt
     1381 gttatttaat actggtaatt ttatattaga tgctatatta agtgaaaaga aagaggtttg
     1441 tgataagaat gatatagaac taaaaatagg aataaatttt agttgttgtg aagctgttga
     1501 attagtggat atatgtcata tattttcaaa tattttagac aatgcaattg aggcatgtaa
     1561 taaaattgat agtggaaata gagttatttg tgttaaaggt gatgttatgc aaaattttta
     1621 tttaataaga gttgaaaata ctaagataaa taagattatt actaaaaatg gagatatttt
     1681 gacagacaaa aaaggttctc ttcatggact tggaataaaa agtgtaaaaa actctgtaaa
     1741 taagtatggt ggtaatgttg taattgaata tgatgataaa aaatttgtag ttaaaattgc
     1801 tattccactt agaaatgtga agaaagcagt taatcatgtg atttaaatgt atataaattt
     1861 gatgtgtaga aatttaatat ataagaatta atgtataaaa gtgatgcata gaagtttaat
     1921 atataagaat taatgtataa aagtgatgca tagaagttta atatataaga actaatgtat
     1981 aaaagtgatg cataaaagtt taatatataa gaatttaata tgtataaaag tgatgcataa
     2041 aagtttaata tataggaatt taatatgtat aaaagtgatg catagaaatt taatatataa
     2101 gaatttaata tgtataaatg tggtgcatag aagtttaatg taaaaatttg gtgtataaga
     2161 atttaatata tatatattta ttttaataat ttatattttg tttagggtat ggtaaatcgt
     2221 ggtattaaat aagtagattt taatagttaa attatagtca attataataa agctatttaa
     2281 tctacttttt taatataaaa atataagggg gaatttgtaa tggcttgtaa cacttgtaaa
     2341 atgtgcgaaa gtgcagacaa gaaattagaa agttttgtag cttcaaagga tgttgaaaca
     2401 gcatttcata gaacagaaga tcagaaagtt aagtgtggtt ttggacttca gggggtttgt
     2461 tgtagactct gttcaaatgg accatgtaga gtaactccta aatcaccaag aggtatatgt
     2521 ggagcagatg cagacactat agtagcaaga aactttttaa gagcagtagc atcaggagca
     2581 gcttgttatt tacatgtggt agaaaataca gctaagaatt taaaaaatgt tggaataact
     2641 aaaggtgttg ttaaaggaga aaaaacatta aatcaattag cagagatgtt tggaatagaa
     2701 agtgatgaaa agtatgataa atgtataaag gttgcagaca aagttatcaa cgatttgtat
     2761 aaatcaagag atgataaaat ggaattagta gaaaaaatag cttatgcacc tagagtgaaa
     2821 aagtggaaag agttaggtat aatgcctggt ggtgcaaagt cagaagtttt tgatgcaata
     2881 gtaaaatcat caacaaattt aaatagtgac ccagtagaca tgctagttaa ttgtttgaac
     2941 ttaggtatat caacaggatt atatggtctt acactaacta atcttttaaa tgatgttatg
     3001 ttgggagaac cagttataag aatggctcct gtaggattta atgtaataga cccagactac
     3061 ataaatataa tgataacagg ccatcaacat tcaacatttg caaatttcca agatagatta
     3121 aaagatgaag atgttataaa attagctcaa tctgttggtg caaaaggctt taagctagta
     3181 ggatgtacat gtgttggtca agatttacaa ttaagaggag aacattatca agaagtattt
     3241 gctggacatg caggtaacaa ttttacaagt gaggctgttt tatcaactgg agcaatagat
     3301 atagttcttt cagaatttaa ctgtactata ccagggcttg aaccaatagc agataaatat
     3361 aaagtaaaaa tggtttgttt agatgatgtt gctaaaaaag cgaatgcaga atacataggt
     3421 ttagacagaa gtaaattaga tgaacttagt aacactttaa tagaaaaagc attggagtct
     3481 tataaggaga gaagaggaag tattgaaata gatataccaa aagaccatgg atttgaacaa
     3541 tctttaactg gtgtaagtga aaagaacctg aaagcgtttt taggagattc atggaaacct
     3601 cttattaatt taattgcaga aggaaaaatt aaaggtgttg cagctgttgt aggatgttca
     3661 aatatgacag caggaggaca tgatgtaaat actgttgaac ttactaaaga attgattaaa
     3721 aaagatataa tagtactatc tgcaggatgt tctactggag gattagaaaa tgttggtctt
     3781 atgtcacctg gagcagaaga attagcagga gaaaacttaa aagaagtatg taagacttta
     3841 ggaataccac cagtattaaa ctttggacca tgtctagcta taggaagact agaaatagta
     3901 gcaacagaat tagcagctga acttggaatt gacctaccac aattaccatt agtgctttca
     3961 gctccacaat ggttggaaga acaagcatta gctgatggag cgtttggtct tgcccttggc
     4021 ttacctcttc atttagcttt acctccattt ataacaggag gaaaattggt gacagaagta
     4081 ttaacagaaa aattaaaaga cttaacagga ggacatgtta tagtgaatcc agaccctaaa
     4141 tcttcagcta atcaattaga agaaataata atagatagaa gaaaaaattt agggttaaag
     4201 gatgtggaat gcaatgcata gaatttttat aaataaagat ttatgtacag gatgtaagag
     4261 ctgtgtacta gcatgtatgc taaaacacaa taaagattat gacatgtaca ctcttgattt
     4321 agaaaatata gataatgata gtagagggca tatagaatta gatagtaaac ataataatcc
     4381 agttccaatt ctttgtagac actgtgatga acctgaatgt gtattagcat gtatgagtgg
     4441 tgcaatgcat aaagatagtg aaagtggaat cgtttcatat gatgaagaga aatgtggttc
     4501 atgttatatg tgtgtaatgt cttgtccata tggattatta aagccagatg atagaagcaa
     4561 gcagaacata cttaaatgtg atttatgtaa agatgaggag tatcctagat gtgtagctaa
     4621 ttgcccaagt ggagcaattg aattacagaa ggaggaaaat gatgaattat gtagtgttag
     4681 gggctagtgc agctggtata aatgcagtaa aaacattaag agaattagat aaagattcaa
     4741 atatagtagt aatttctaaa gatgaaaacg tatattcaag atgtatgttg catcacgtta
     4801 tatctgaaca cagaatttta aaacaaataa attttgttga tgaagatttt atggagcaaa
     4861 ataatgtaaa atggattgca ggtaagactg ttaaaggtat agacataaat aaaaaggtag
     4921 ttcagacaga agacattact gtaaattatg ataaactttt aatagctaca ggtgcatctt
     4981 ctgctattcc tcctataaaa aatttaagag atggaaattt tgtatattct gtgagaaaca
     5041 tagatgatat ttataaaata aaagaaaaag cacaaaattc taaaaatgta gttataatag
     5101 gtgctggttt agttggtata gatgcattag tgggattatt taaatatgag cagttaaata
     5161 tttctgtagc ttttatggaa aagtacattt tagatagaca attggatgaa tatacagcat
     5221 cagtgtatga aaataagttc aaagaaaaag gtgtaaaatt ttacccaagt gcatcaatac
     5281 aagaaattgt attggataac agtaaaaatg ttacaggtgt tgcattttca aatggtgaag
     5341 ttttagatgc agacatggta attgttgcta caggggttaa accaaatgct gactttttag
     5401 atggaacagg aatagaatat gatagaggta taataataga tgatatgtgc caaacaacac
     5461 aaaaagacat atatgcagca ggagatgttg taggtaaaaa tgctatttgg cctctggcag
     5521 taaagcaagg aattgtagct gcctataata tggttggaaa agataagaag atagaagatg
     5581 aatttgcttt taaaaacagt atgaatttca tggatatacc aactatttct ataggaatga
     5641 atacacctgt agatgatagc tataaagtgc taactagaca tggaattaat gattataaaa
     5701 agtttgtttt taaagataat gtaatctatg gagcagttat acaaggagat atttcatatg
     5761 taggtgtatt aacttattta ataaaaaata aagttgaaat atatgattta gaaaatagga
     5821 tatttgatat atgttatgca gactttttta atataaaaga aaatggagaa ttttgttata
     5881 gtgtatagta tatacgtgga gtaaggttta taaatacagt aaatcaataa atagagttat
     5941 tctaaaataa gaaaaatgac aaatcttatt tagaaatagc tctatttttt gtaattaaat
     6001 ttaaattata ttcaatttgt aaaatattat tttgaacaat tatacatata ctctctagtt
     6061 agaggtaaat cattttttat acctttagtg aaaagtattt gatgtatatc tataatacca
     6121 gtgttgaaag cagcagcaca agaacaaagg tataaatccc acattcttat aaacttatca
     6181 tcaaacattt ctttaatctt tggaagattc tcagagaaat ttttttgcca gtatagtaag
     6241 gtttttacat aatgtaatct tagactttct acgtctatag tatgatattt gtaatcacta
     6301 caaatatgta tcatttctct taggctagga ataactcctc ctgggaaaat atattttttt
     6361 atccaagggt ctccataaga ttcctgcaat ccacttatat agtgaagtaa aaacaatcca
     6421 ccatctttta aaacagcatt tacgttttta atgaaaagtt catagttttc tctaccaaca
     6481 tgttcaagca tcccaacgct tacaattcta tcaaacataa ggtctgattt ttttaattct
     6541 ctatagtcca taagtcttac ttcaagatag tcttgaaggt tctcttcttt aattcttgcg
     6601 ttaaattcct taaattgctc ttcgctaagt gtaattccaa cgccgtgaat tttatatttt
     6661 tttgcagctt ctattagtaa aaatccccaa ccacaaccaa tatcgagaag gctcatacct
     6721 tcctctaaat ttagtttagt taatatgtgg tgaactttat tgacttgagc atcataaaga
     6781 gtatcattat catttctaaa gtatgcacaa gaataactaa gtgtcttatc taaccataag
     6841 ctataaaaat cgttgccaat gtcatagtgg gcatgtattt ctttcttttg atgtctcatt
     6901 gaatttgatg agtgcaatag atgttttaca gctgaattat caatattgaa tttgtctatt
     6961 tgttttaaaa gtagatttaa agttaagaat aaatctccct caacttcaat gtctctattt
     7021 atgtaggctt ctccaagtgc taaagatgta ctttttaata gttcagactt gctaatatca
     7081 ttatttacta taactttgaa ctgaggggag ccctctccaa ttagaaattc ttcctcatct
     7141 ttaagcctaa ctagaaatgg tgtttcacca aatttctcta aatagtcttt taaaaaattt
     7201 tttgtaatat tcatattacc agctccttct aatgtaaatc cagtaagttt ccct
//
LOCUS       DAYAOO010000140         7248 bp    DNA     linear   BCT 12-OCT-2024
DEFINITION  TPA_asm: Clostridioides difficile isolate ST8-SSI-h139-18
            SAMN40601845-rid21577343.denovo.144, whole genome shotgun sequence.
ACCESSION   DAYAOO010000140 DAYAOO010000000
VERSION     DAYAOO010000140.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN40601845
            Sequence Read Archive: SRR28438827
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 7248)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7248)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-MAY-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-MAY-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002157583.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002157583.1
            Genome Coverage       :: 163x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/11/2024 16:19:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 4,038
            CDSs (total)                      :: 3,963
            Genes (coding)                    :: 3,930
            CDSs (with protein)               :: 3,930
            Genes (RNA)                       :: 75
            rRNAs                             :: 6, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 60
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 33
            CDSs (without protein)            :: 33
            Pseudo Genes (ambiguous residues) :: 0 of 33
            Pseudo Genes (frameshifted)       :: 7 of 33
            Pseudo Genes (incomplete)         :: 25 of 33
            Pseudo Genes (internal stop)      :: 11 of 33
            Pseudo Genes (multiple problems)  :: 8 of 33
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7248
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN40601845-rid21577343.denovo.144"
                     /isolate="ST8-SSI-h139-18"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Denmark"
                     /collection_date="2018"
                     /collected_by="Statens Serum Institute"
     gene            complement(162..1001)
                     /locus_tag="ACGI5H_003679"
     CDS             complement(162..1001)
                     /locus_tag="ACGI5H_003679"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:1902495 - transmembrane transporter
                     complex [Evidence IEA];
                     GO_function: GO:0016301 - kinase activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA];
                     GO_process: GO:0016310 - phosphorylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system mannose/fructose/sorbose family
                     transporter subunit IID"
                     /protein_id="HFG9699361.1"
                     /translation="MSDIKNEVSKKTLSKKDVIKSWLRWFFFAQSNYNYERLQSTAFS
                     HSMLPVLKKLYPDKEELKQEVETHLAFFNTEPICGCVIHGITIAMEEEKANGADEISG
                     DGMNAIKTGLMGPLAGIGDTLTQGVITPIVLAVCIGLTEGGASIAGPILFVIAQYIIM
                     TSISFGMWTNGYKYGKKAVESILQGGIVNKVIEGASILGTLVMGGLVGRFINLSTPIS
                     YTSGDFKFSLQTDLLDKIFPGLIPLVLTLLVLFALKKGLSPIKIMFILIVVGAITGIL
                     GLF"
     gene            complement(1025..1783)
                     /locus_tag="ACGI5H_003680"
     CDS             complement(1025..1783)
                     /locus_tag="ACGI5H_003680"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895533.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS
                     mannose/fructose/sorbose/N-acetylgalactosamine transporter
                     subunit IIC"
                     /protein_id="HFG9699362.1"
                     /translation="MHISLIQAVLIAIFYYLSWSPWLTYVGFFTWNRPLLAGFVTGII
                     LGDPVQGAIIGAGINMIYLGFISAGGAQMGDPAFAGYVGTALAIASKLDVSTAMAIAV
                     PLGTVATVLWIGKMTVNSFFAHWADREVQKGNVDRVAFINIVPPQILLFAMSFIPALL
                     VVYFGPNAIDGMLEVMNDNVLHVFNVIGAMLPALGIAMNLKLIGNKFTMPFFILGILM
                     AVYFKVDIIVISVIGVILALTITSIKYGKDSATS"
     gene            complement(1830..2303)
                     /locus_tag="ACGI5H_003681"
     CDS             complement(1830..2303)
                     /locus_tag="ACGI5H_003681"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888320.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system
                     mannose/fructose/N-acetylgalactosamine-transporter subunit
                     IIB"
                     /protein_id="HFG9699363.1"
                     /translation="MSNIALTRIDDRLIHGQVITAWCKITSAKRIVIVDDLVVKDPFI
                     VQVLQMAAPSTVKVEVHDVESGAEVLKSHNGDENLIVLVKYPKTVLGLVNSGVDLKEL
                     NVGGMGAGLGRKSFYKNISVSDEEKEIFRELISKDVKCFIQIVPDAKKIDVGTLL"
     gene            complement(2332..2748)
                     /locus_tag="ACGI5H_003682"
     CDS             complement(2332..2748)
                     /locus_tag="ACGI5H_003682"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426358.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:1902495 - transmembrane transporter
                     complex [Evidence IEA];
                     GO_function: GO:0016301 - kinase activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA];
                     GO_process: GO:0016310 - phosphorylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HFG9699364.1"
                     /translation="MIHMAGIIIATHGNMAKAMLESAELIVGKQENVETLGLNHGDSI
                     DEFSRKLEDGIEKYKDEGVLVLLDFYGGTPFNTSAIVINKFAKVCELECLTGVNLPML
                     LELFLNRDTMKLKDLKNLCEEVGISGIKDVKTVLKL"
     gene            complement(2795..3847)
                     /locus_tag="ACGI5H_003683"
     CDS             complement(2795..3847)
                     /locus_tag="ACGI5H_003683"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426357.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactitol-1-phosphate 5-dehydrogenase"
                     /protein_id="HFG9699365.1"
                     /translation="MKSVRFYGIRDTRVEDVDVPKILEKDDVIIKVKVAGICGSDISK
                     YSKTGPHMVGEILGHEFSGEVAQVGKEVRSFKIGDRVAVCPAMPCFECDECKKGLYSR
                     CNNVAIIGNKELGGCFAEYTKVKERNLIKIPDEISYETAAALEPVCIAGHGLFRSEAK
                     VGDTVVVLGTGPIGLFSIQWAKIFGSTKIIAVDVFDEKLDLAKELGADICINAKEKNI
                     VEEIKRLTDGDGADIVIESAGTPLTCGQVLLLAKKGGTVLYAGVPYGDVALTREQFEK
                     IVRSELTVKGTWFGNSFPFPGKEWSAGLYHMQKGDMNVEKLVTHRINLEEVPAYFEKV
                     YKRDIFFGKIMINIDN"
     gene            4243..4923
                     /locus_tag="ACGI5H_003684"
     CDS             4243..4923
                     /locus_tag="ACGI5H_003684"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426355.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylaminoimidazolesuccinocarboxamide
                     synthase"
                     /protein_id="HFG9699366.1"
                     /translation="MKKVYQGKTKDVFELDNGNYLLKFKDDVTGKDGVFDPGENSVGL
                     SIDGIGRANLETSVKFFEILNNAGIKTHYVSANLEEATMEVLPAKVFGNGLEVICRYR
                     AVGSFLRRYGSCVEEGAKLDCYVEATLKDDDRCDPLITSEGLEALNIMTQAQFDSMKS
                     MTQKISNIVRDTIAEKGLELYDIKFEFGFYNDEVILIDEIASGNMRVYKDGVIVDPMD
                     LTALLLDK"
     gene            complement(5056..5376)
                     /gene="sugE"
                     /locus_tag="ACGI5H_003685"
     CDS             complement(5056..5376)
                     /gene="sugE"
                     /locus_tag="ACGI5H_003685"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417824.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="quaternary ammonium compound efflux SMR
                     transporter SugE"
                     /protein_id="HFG9699367.1"
                     /translation="MKWLFLFVAGLFEVFWAFQLKNSHGFSKLTPSILTVVGMIVSFY
                     FLSLALKHLPLGTSYAIWTGIGTVGTAIVGMAILNEPISISRIACIGFIVVGIVGLKL
                     LSTN"
     regulatory      complement(5446..5552)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00442"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="guanidine-I (ykkC/yxkD leader) riboswitch;
                     Guanidine-I riboswitches control genes whose products are
                     involved in modification or pumping out guanidine as a
                     toxic compound from bacteria; This is class of guanidine
                     riboswitches is based on the ykkC/yxkD leader; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /bound_moiety="guanidine"
                     /db_xref="RFAM:RF00442"
     gene            5758..6585
                     /locus_tag="ACGI5H_003686"
     CDS             5758..6585
                     /locus_tag="ACGI5H_003686"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434776.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbon-nitrogen hydrolase family protein"
                     /protein_id="HFG9699368.1"
                     /translation="MNFYKIAVCQMITTENKIENINHAVDMVTEAAINGAKIVVLPEM
                     FNCPYENKYFPKFAEEYPGETTTILSKLAEKHGIYLVSGSIPELEDGKIYNTCYVFDK
                     NGALIGKHRKMHLFDIEVTGKVSFKESDTLTAGNDVTVIDTEYGKVGIAICYDIRFPE
                     LSRLMALKGAEIVILPAAFNMTTGPAHWELSIRMRALDNQIFYVGAAPARNMNASYIA
                     FGNSRISDPWGRIIAQADEKECIIYADIDRDLIPDIRQQLPLLKHRRTDLYELNTLK"
BASE COUNT         2458 a         1312 c          840 g         2638 t
ORIGIN      
        1 actttttaaa atattaaata ctacatatag cttacataag tttaaaattt aatctattat
       61 aaaattaccc taattgccaa actttttaat ataaattttc caacatccta caaatataat
      121 caatagatat agaatcctaa cttacaccaa tatatattta tttaaaatag tcctaaaata
      181 cctgtaatag ctcccactac tatcagtata aacattattt ttattggaga aagacctttt
      241 tttaatgcaa agagtactaa taaagtaagt accaaaggaa ttaatcctgg aaatatctta
      301 tcaagtaaat ccgtttgaag actaaattta aaatcaccac tagtataact tattggtgta
      361 gataaattga taaacctacc tacaagcccc cccatgacta aggtacctag tatagaagcc
      421 ccttctataa ccttatttac tattccacct tgaagtatac tttcaacagc ttttttccca
      481 tacttatatc catttgtcca cattccaaaa gaaattgaag tcattattat atattgagct
      541 attacaaata atataggtcc tgcaattgat gctcctccct cagttaaacc aatacaaaca
      601 gctaacacta taggagttat aactccttga gttaaagtat ctccaattcc cgctagtgga
      661 cccatcaagc ctgttttgat agcattcata ccatctccac ttatttcatc tgctccatta
      721 gctttttctt cttccatagc tattgttatt ccatgtataa cacatccaca tataggttct
      781 gtgttaaaaa atgctagatg agtctccact tcttgtttta actcttcctt atctggatat
      841 aattttttaa gtactggcaa cattgaatgt gaaaaagctg ttgattgcaa tctttcataa
      901 ttgtaattag attgtgcaaa gaaaaaccat cttaaccatg attttattac atctttcttg
      961 cttaacgttt tcttagatac ttcatttttt atatctgaca taatattttc cccctcacat
     1021 gtatttaaga tgtagcacta tcttttccgt acttaattga agtaattgta agagcaagta
     1081 ttactccaat aacagatatt actattatat ctactttaaa ataaacagcc attagtattc
     1141 ctaatatgaa aaagggcata gtaaacttat ttccaatcaa ttttaaattc atagcaatcc
     1201 caagtgctgg caacatagcc ccaattacat taaatacatg taacacatta tcattcatta
     1261 cttccaacat accatctatc gcatttggac caaaataaac aactaataat gctggtataa
     1321 aactcattgc aaataacagt atctgtggtg gtactatatt tataaatgct actctatcaa
     1381 cattcccttt ttgaacctct ctatcagccc aatgtgcaaa aaaagaattt actgtcatct
     1441 ttccaatcca aagtacagtt gcaacagttc ccaatggtac agctattgcc attgcagtac
     1501 ttacatctag cttagatgct atagctaaag cagtacctac atatcctgca aaagctgggt
     1561 cccccatctg agctccccct gctgatataa aacctagata tatcatattt atacctgctc
     1621 ctataattgc tccttgaaca gggtctccta atataattcc cgttacaaat ccagccaata
     1681 gaggtctatt ccatgtaaaa aatccaacat aagtcaacca cggactccaa gaaagataat
     1741 aaaaaattgc tattaatact gcttgaatta gtgaaatgtg catattcttc ctccctattt
     1801 tcttttaaag atttacaaga tagtcttctt tacaataatg ttcctacatc aattttcttt
     1861 gcatctggta ctatttgtat aaagcattta acatcttttg atattagctc tctaaatatt
     1921 tctttttctt catctgacac agatatattt ttataaaaac tttttctacc aagccctgct
     1981 cccatacctc caacattcaa ttcctttaaa tctaccccac tatttactaa acctaagaca
     2041 gttttagggt atttgaccaa tactattaaa ttttcatctc cattatgtga ttttaagact
     2101 tcagcacctg attctacatc atgtacttca accttaacag ttgatggagc tgccatttgt
     2161 aaaacttgaa ctataaatgg gtcctttact actaaatcat ccacgattac tatccttttt
     2221 gctgatgtaa tcttacacca agcagtaata acttgcccat gtattaatct atcatcaatt
     2281 cttgttaatg ctatattact cataattatt cctccagatt tttaatttat tttacaactt
     2341 taaaacagtt ttaacatctt tgattcctga tatcccaact tcctcacata aattcttcaa
     2401 gtcttttaac ttcatagtat ctctgtttaa aaataactct aaaagcatag gtaaatttac
     2461 acctgtcaaa cattctaact cacatacctt agcaaattta tttattacaa tagcagatgt
     2521 attaaatgga gttccgccat aaaaatcaag caatactaaa accccttcat ccttatattt
     2581 ctcaattcca tcttctaact ttctactaaa ctcatctatg ctgtcaccat ggtttaatcc
     2641 taaagtttct acattttcct gtttgcctac tattaattca gcactttcta acattgcttt
     2701 agccatattt ccatgtgtgg ctataattat tcctgccata tgaatcatac ctttcttaac
     2761 cttttttata tggattatta tttagtactc taatctaatt atctatatta atcattatct
     2821 taccaaagaa aatatccctt ttgtatactt tttcaaaata agctggtact tcttctaaat
     2881 ttattctatg tgttactaat ttttcaacat tcatatcacc cttttgcata tgatacaatc
     2941 cagcactcca ttcttttcct gggaatggaa aggagtttcc aaaccaagtt ccctttacag
     3001 ttaattcact tcttactatc ttttcaaatt gctctctagt caaagctaca tccccatatg
     3061 gtacacctgc atacaatact gtacctccct ttttagctag caacagtact tgaccacatg
     3121 tcagtggagt accagccgat tcaataacaa tatctgcacc atctccatca gttaaccttt
     3181 ttatttcttc tacaatattc ttttcttttg catttataca aatatctgcc cctaactctt
     3241 ttgccaagtc taacttctca tcaaatacat ccacagctat tatttttgta gaaccaaata
     3301 tttttgccca ttgtattgaa aataatccta ttggacctgt accaagtact acaacagtat
     3361 ctccaacttt agcttctgac ctaaaaagac catgtcctgc tatacatact ggttctagcg
     3421 cagcggcagt ctcataactt atctcatctg gtatttttat taaatttctc tctttcacct
     3481 ttgtatactc tgcaaaacaa cctccaagtt ctttatttcc tattattgct acattattac
     3541 atcttgaata caagcctttt ttacattcat cacattcaaa acatggcata gctggacaaa
     3601 cagcaactct atctcctatt ttaaaactcc ttacttcttt accaacctgt gccacttctc
     3661 cagaaaattc atgccctaaa atttctccaa ccatatgtgg acctgtcttt gaatattttg
     3721 atatatcaga accacatatt ccagctactt ttactttaat tattacatca tctttttcta
     3781 atatttttgg tacatccaca tcctccactc ttgtgtctct tataccatag aatctaactg
     3841 acttcactat taaccacccc tactttttat ttgagaatat atccctattg tttatatgtt
     3901 aaatatctaa agcaactttc atgccaatat atgtaagcat tgtattcatg cattttataa
     3961 aattatcatt aaatgtgtgt caaagtgtgt caaaagtttc ttatattaaa acttatgtgt
     4021 gtcaatataa acgacactaa cattttatat tagttctctt attataagtt ttataaaatg
     4081 tacttttttt gttattttta taaaattgtt cggaaatttc ccttctattt gtgatataat
     4141 attaaatata aggtatcaat ataaattttc atgcgaatat cagaactttt ttgacactaa
     4201 tgccttattc aatataataa tttaactttt tggaggttgt ttatgaaaaa agtgtatcaa
     4261 ggaaagacta aagatgtttt tgaattagat aatggaaatt acttacttaa atttaaagac
     4321 gatgtaactg gtaaagatgg agtatttgac ccaggcgaaa atagtgtagg tctaagtata
     4381 gatggaattg gtagagctaa tttagagaca tctgttaagt tctttgaaat tctaaacaat
     4441 gctggaatta aaactcatta tgtaagtgct aatttagaag aagcaactat ggaagttcta
     4501 ccagcaaaag tttttggtaa tggattagaa gttatttgtc gttatagagc tgtaggtagt
     4561 ttcttacgtc gttatggttc atgtgttgaa gaaggtgcta aactagattg ttacgtagaa
     4621 gcaactttaa aagatgatga ccgttgtgac cctcttataa catctgaagg tttagaagct
     4681 ttaaacatta tgactcaagc tcaatttgat tcaatgaaaa gcatgactca aaaaatttct
     4741 aacatagttc gtgatactat agctgaaaaa ggtcttgagc tttatgatat taaatttgaa
     4801 tttggattct acaatgatga agtaatctta atagatgaaa tagcatctgg aaatatgcgt
     4861 gtttataaag atggtgtaat agttgaccct atggatttaa ctgctctttt attagataaa
     4921 tagtatatac atataattta caaatataat aaacttataa ataagataag ctatgaagta
     4981 aagacttttt aaatgttgat tatttttaaa cattttctcg cctttaattt catagcttat
     5041 ttaaattaat atactctaat tagtagataa tagctttaac cctacaattc ccaccacaat
     5101 aaaacctata catgcaattc ttgatatact aataggctca tttaaaatag ccatgcctac
     5161 aatagctgta ccgacggtac caattccagt ccatattgca tatgaagttc caagtggaag
     5221 atgttttagt gctaatgaca aaaaataaaa acttacaatc attccaacaa cagtaagtat
     5281 acttggagtt aatttagaaa atccatgtga attttttagt tgaaaagccc aaaacacttc
     5341 aaacaaacct gcaacaaaca aaaataacca tttcataaat tcatccctct tttcaaatat
     5401 gtctcttatt tttccaataa aataacctga gaaatattat aaaatatctc ccaggttttt
     5461 gtccttccgt gttcacaaca aaaactatgt tgtgggtttt atctcggacc agaccaatca
     5521 ttaataattg cggaacccta taaaactcta ttaattattc tattttatct ataataatac
     5581 tatcaacata tataaaaaaa gtcaatatat gggttccata tataataaaa ataactttta
     5641 tatacctttt aatattctta ttcacttctc tccataccca tttgggtcaa tctaagaata
     5701 tctaattttt atttaatatg ttataataac ataaaaatat tgaaaggagt aatttctatg
     5761 aatttctata aaattgcagt atgtcagatg attactacag aaaataaaat tgaaaatatc
     5821 aatcatgctg tagatatggt aacagaagct gccatcaatg gagctaaaat tgtagttttg
     5881 ccagaaatgt ttaactgccc atatgaaaat aaatattttc ctaaatttgc tgaagaatat
     5941 ccaggtgaaa caacaacgat attaagtaaa ttagctgaga aacatggaat ttatctagtt
     6001 tctggtagta ttcctgagtt agaagatgga aaaatctata atacttgcta tgtatttgat
     6061 aaaaatggag ctctaattgg aaaacatcgt aaaatgcact tatttgacat tgaagttaca
     6121 ggaaaagtta gttttaaaga atcagatact cttacagctg gaaatgatgt cactgtaata
     6181 gataccgaat atggaaaagt tggtatagct atttgctatg atattcgttt ccctgagtta
     6241 tcacgtttaa tggctcttaa aggtgctgaa atcgttatct tacctgctgc atttaatatg
     6301 actactggtc ccgcccattg ggagttatct ataagaatgc gtgctttaga taatcagata
     6361 ttctatgttg gtgctgcacc tgctagaaat atgaatgctt cttatatagc ttttggaaat
     6421 tcaagaattt cagacccttg gggaagaata attgctcaag ctgatgaaaa agaatgtatt
     6481 atttatgctg acattgatag agatttaatt cctgacataa gacaacagtt accacttctt
     6541 aagcacagaa gaactgattt atatgaactt aatactttga aataaaacag aacataaccc
     6601 cataaatcat aaattaagtg ttaaaaaaat ttatggggtt ctcattaatt tgatttaaaa
     6661 ttaatttcat aaaaataatg ctaatattaa tttaattaaa taatactaat aattactaat
     6721 gattatgcta attatcagca tttactaatt taatcactat tagttatttc ttttattaaa
     6781 tatctttact tttttactta ttatgtcttc tagctttaca tttggattat ggtatttctt
     6841 tctattttta gtcacatctt tctattgaat tacttgctta aaacaccaat gcacacatgc
     6901 cagataatgt tcacaattat ttagaaatct tgctctacct tcttcaatgt tgatattatc
     6961 tctcctagtt gatattatct ttcctaaaat ttcttttaat taaaaaacaa cattagttga
     7021 tatatcaagt atattttaag caactgaaaa aaacaataat aattgatata tcaactaatt
     7081 aatgtagatt aattcatttt tataatttat atacttttta attaatctac cttatttaat
     7141 taaaatcctt cctttctatt tatccatttt caacttaaat tataagattt catcagctat
     7201 atttttgcat accaataatt attaaatatc aaatatatat tctattaa
//
LOCUS       DAYAOO010000141         7194 bp    DNA     linear   BCT 12-OCT-2024
DEFINITION  TPA_asm: Clostridioides difficile isolate ST8-SSI-h139-18
            SAMN40601845-rid21577343.denovo.145, whole genome shotgun sequence.
ACCESSION   DAYAOO010000141 DAYAOO010000000
VERSION     DAYAOO010000141.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN40601845
            Sequence Read Archive: SRR28438827
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 7194)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7194)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-MAY-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-MAY-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002157583.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002157583.1
            Genome Coverage       :: 163x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/11/2024 16:19:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 4,038
            CDSs (total)                      :: 3,963
            Genes (coding)                    :: 3,930
            CDSs (with protein)               :: 3,930
            Genes (RNA)                       :: 75
            rRNAs                             :: 6, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 60
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 33
            CDSs (without protein)            :: 33
            Pseudo Genes (ambiguous residues) :: 0 of 33
            Pseudo Genes (frameshifted)       :: 7 of 33
            Pseudo Genes (incomplete)         :: 25 of 33
            Pseudo Genes (internal stop)      :: 11 of 33
            Pseudo Genes (multiple problems)  :: 8 of 33
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7194
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN40601845-rid21577343.denovo.145"
                     /isolate="ST8-SSI-h139-18"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Denmark"
                     /collection_date="2018"
                     /collected_by="Statens Serum Institute"
     gene            163..1056
                     /locus_tag="ACGI5H_003687"
     CDS             163..1056
                     /locus_tag="ACGI5H_003687"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902037.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0070007 - glutamic-type endopeptidase
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family glutamic-type intramembrane
                     protease"
                     /protein_id="HFG9699369.1"
                     /translation="MQLYNTPFNTNKHLIYFFTFTLVLNWIFSLTPALLGITNTILGE
                     IIFYLAYTSPAIVGLFFISTIYPQSAKQDFIYRYLSFKEIGIKWILLTILFFALTFIT
                     SLIIGNYFNVKTSDIDWIHIAVFRPSKIAYMLLASFILSILSQEAGWRGYAIDKLLVR
                     FGFIGSSIILGLVCGIWYLGSYFTPNQIPYNLAQYSLFDAFLFIPNIVLLNFIINFVY
                     INTSRSILSAGLVHMMYYFFNIQLLLHYPIKLCVIAQYVQIIFGLIFLVYMISSNKFK
                     QKVNSEIEQIKSDDFEFELDW"
     gene            1234..2058
                     /locus_tag="ACGI5H_003688"
     CDS             1234..2058
                     /locus_tag="ACGI5H_003688"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437657.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HFG9699370.1"
                     /translation="MFKIGEVSKLTQISIRMLRYYDELGILKPAKTDKYTGHRLYSVE
                     QISILQRIVLLRDSKFSVAEIANIVHNWNDEFVIKELNRKKNEIQKEIKQEQQRINKI
                     DKFIEAINCDKDEIHYNVVFKKIPSYKIISLREIIPDYQSEGILWEKLSKFIKEEHIE
                     VSRQSNNNIAFYHDEEVKDNGVDIEVGMVVKKIGKNKSGFIYRETEEIDMMACTMVYG
                     PYENIAGAYESFCYWLDKNSDYQISGINRQIGHKGEHNEINPENYLTEIQIPLIKV"
     gene            2184..2765
                     /locus_tag="ACGI5H_003689"
     CDS             2184..2765
                     /locus_tag="ACGI5H_003689"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888409.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HFG9699371.1"
                     /translation="MKADSTKEQLINATIQLLSSHRDVSSITAREIVAKANVNLAMIN
                     YYFKSKEELINISIKKFLKRHMDEYKATHDTKNLAPKQQLREILIAFFDFIGEHSQFI
                     KISVPYILIQEEIVYPFEILPLIKAHYENQNNKKTEAEYRTIAYQITSFIQLLFLRSN
                     AFFKYSGIDILNIEQRNGLIDFQLDLLLVDITK"
     gene            2869..3045
                     /locus_tag="ACGI5H_003690"
     CDS             2869..3045
                     /locus_tag="ACGI5H_003690"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418084.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9699372.1"
                     /translation="MFFTFIGVISAILLLCTIICGLWIKLNNRNNDSNSHFTFSILSI
                     AFSLLIVVAFLVRN"
     gene            4311..5063
                     /locus_tag="ACGI5H_003691"
     CDS             4311..5063
                     /locus_tag="ACGI5H_003691"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728886.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HFG9699373.1"
                     /translation="MLKVNQLCKSYKTGSKTYPVLKNISFEINKGEFVAIMGSSGSGK
                     TTLLNCISCFIPIDNGEIILGNNNIRNLKEKELSEVRNQQLGFVFQDFMLFDGLSVFE
                     NICVPQIIKGSQVLQMENRAINLCELFGIEHIRKKYPAEISGGEKQRTAVARALMNNP
                     DLILADEPTGNLDSKSCRTVIESFLKAKQELDATILMVTHDSFAASFCDRVIVLKDGI
                     IYKEVVKSNSRHKFLDELLEVLKEMGGAQDDN"
     gene            5053..7164
                     /locus_tag="ACGI5H_003692"
     CDS             5053..7164
                     /locus_tag="ACGI5H_003692"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895629.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HFG9699374.1"
                     /translation="MTINKLYSKLRAYNWKNYTTLFFCIILSVVLVTSYALIYFSPTI
                     QNILPTGGDSRKQATMIFSVAILGCAVFTTYASSLFLKFKSKEIGIFMALGTDKKKLK
                     KLLFSEILLISIVCCFLGLILSIPVSFGIWKIFQLVIIDTREMTYHFGTQGFIYGFIF
                     SVFVTLCIFILSVKFINRTNIIDILNDQRISEPIQDVKDWYGILGIIFIILGIFLGYL
                     VPSLTINKLNYKLPSIWSFTYLLSLIGIYMIMTYIVVHAKRGKHPEKYYKNIISTSMM
                     RFMGRQTVKNMCVISFLIAGALFAVFYVPNMVTGIYDTLKNNPIDYTFTYNQRDKQVS
                     KKDIEQLADKHNIKIQNYMEIPSIELIVDGVESIYHKDGTIEKVYMKKSSYDMFFNSK
                     DFSKLIGKPITIKNGEYLAVVNKGNENQDYKYTKFISSPVTEKEIPFRYAGKIIFNGS
                     FFQNRSMNAYVLNEEDYKSFTKDLSIKNYNNSILFNVDKDTYAFANDLKKEIIKRTSK
                     EMGMFSGYDEYVKKRYESTGRKYFMDEEYPSGEGHLKLDPNNNQLYLNWKYYPNFKIL
                     QSQDMIKNMAVFLMLFIYVAIICFTAVGIIAYTRGVTIAINHKQVFMDLNRLGANNDY
                     IKFCIRNQLKKVFSYPLIAGSFLIYLFNFMIMLNNDGRIVNSEVNALLINLGFIGICG
                     VYMYLIYLLTYKKFKKIIGIL"
BASE COUNT         2685 a          950 c          951 g         2608 t
ORIGIN      
        1 taattaatta tatttagtgt aaaaataatt aatcaaaata taaaaaatag gatattatta
       61 taggcaataa ctaacatcaa gcgataactt aatacatata aaaataaata aacaattaat
      121 aaaaattaaa acttcattat aaaacggaag gatagtgaaa aaatgcaact atataacacc
      181 ccctttaata caaacaaaca cttaatctat ttctttacat ttactctagt attgaactgg
      241 atattcagtc ttacacctgc gttgctcgga attacaaata caatacttgg agaaatcatt
      301 ttttatcttg catatacatc accagctatt gtaggtctat tttttatttc tacaatctat
      361 ccacaaagtg caaaacaaga ttttatttat agatacctaa gctttaaaga aatcggaata
      421 aaatggatac tattaacaat attatttttt gctttaactt ttattacttc gttaataatc
      481 ggaaattact ttaatgtaaa aacttctgat atagattgga tacacatagc agtgtttaga
      541 ccttctaaaa tagcttatat gctattagca agttttatat tgagtatact tagtcaagaa
      601 gctggatgga gaggatatgc cattgacaaa ttattagtta gatttggatt tataggctct
      661 tcaattattt tagggcttgt ttgtggaatc tggtatctag ggtcgtattt tacacctaat
      721 caaataccat ataatttggc acaatactcc ctatttgatg cttttttatt tataccaaac
      781 attgtacttt taaactttat aattaatttt gtatatatca atacaagtag aagcatttta
      841 tcagctggat tagttcatat gatgtactat tttttcaaca ttcaattact tctacactac
      901 cctattaaat tatgtgtaat agctcaatat gtacaaataa tatttggttt aatatttctt
      961 gtatatatga tttcttctaa taaatttaaa cagaaggtaa attctgaaat tgaacagata
     1021 aagtcggatg attttgaatt tgagttagac tggtaatttt aatatgaatt ataaattaag
     1081 ataatctatg atttgatacg attactactt aaatataatt tactctctat aatttattgc
     1141 aacatctgga aaataattgt atttccacaa acgcttgaag tatataaaaa caaaatatat
     1201 actgattata agtgaaaagg aggtcatatt ttcatgttta aaataggaga ggtttcaaaa
     1261 ctaacacaaa tttctattcg tatgttgcgt tattatgatg aacttggtat tttaaaacct
     1321 gcaaaaacag acaaatatac aggtcataga ttatactcag ttgaacagat ttcaatatta
     1381 caaagaattg tattattgag agattcaaaa tttagcgttg cagaaatagc aaatatcgta
     1441 cataattgga atgatgaatt tgtaattaag gaattgaata gaaaaaagaa tgaaatacaa
     1501 aaggaaataa agcaggaaca acaaagaata aataaaattg ataaatttat agaagctata
     1561 aactgtgata aagatgaaat tcattacaat gttgtcttta aaaagattcc aagttataaa
     1621 atcatatcac ttagagagat aattccagac taccaatctg aaggtatact ctgggaaaag
     1681 ctatctaaat ttatcaaaga agaacatata gaagtatcac gtcaatccaa caataacata
     1741 gctttttacc atgatgaaga agtcaaagat aatggtgtag atattgaagt tggaatggtt
     1801 gtaaagaaga ttggaaagaa caaatctgga tttatatatc gtgagacaga agaaattgat
     1861 atgatggcat gtactatggt ttatggtcca tatgaaaata tagctggtgc atatgaatcg
     1921 ttctgttatt ggttagataa aaatagtgat tatcaaatat caggtataaa tagacaaatc
     1981 ggacataaag gtgaacataa tgaaataaat cctgaaaatt atcttacaga aattcaaatc
     2041 ccccttataa aagtctaata gattagtact taaatactta agtactaatc acccattgac
     2101 atcccaaaat tttcatgata gtatctaaac gtgtattaaa catgtttaat ttttttatgg
     2161 agaaactttt aaggggaaaa attatgaaag cagattcaac aaaggaacaa ttaattaatg
     2221 ccacaatcca gttactatct tcacatagag atgtttcaag cattacggct agagaaattg
     2281 tagctaaagc aaatgtcaat ttagctatga ttaattatta ttttaaatct aaagaggagt
     2341 taattaatat ttctattaaa aaatttttaa agcgtcatat ggatgaatat aaggctacac
     2401 atgatactaa aaatttagca cctaaacagc aattaaggga aatactaatt gcattttttg
     2461 attttatagg tgaacatagt caatttataa agatttctgt accctatata ttgatacagg
     2521 aagaaattgt ttatccattt gagatactac ctttaattaa ggctcactat gaaaatcaga
     2581 ataacaaaaa aactgaagct gaatacagaa ctattgcgta tcaaataact tcatttattc
     2641 agttgctttt tcttcgttct aatgcttttt tcaagtatag tggtattgat attcttaata
     2701 ttgaacagag aaatggttta atagattttc aattagattt attattggta gatattacaa
     2761 aataatacta tattaatttt ttatgtacat ttttttattt tatggtaacg tttgaaaata
     2821 ttctcattga ctaaaaatac ttgcattaaa taagggggag gaattttaat gttttttaca
     2881 tttataggag taatatcagc aattttattg ttgtgtacaa ttatatgtgg tttatggata
     2941 aaacttaata atcgtaataa tgactctaat tctcacttta ctttttcaat actttcaatt
     3001 gctttttcac tgttaattgt ggtggccttt ttagtaagaa attaatgtct ttgttatgct
     3061 gaggtttatt attatagatt tttattattg catgattttt actatattat agtattttta
     3121 ttatattaca gggtcttatt tattatagtg ttttgttgtt acagcatttt attatattac
     3181 agagtcctat ttattatagg atttttatta tattgtaaaa tcttatttat tataggattt
     3241 tgttatatta cagactttta ttatattgaa atctcttatt tattgcagtg tttctattat
     3301 attgcaaact cttatttatt atggtgtttt gttattgcaa catttctatt atattgtaaa
     3361 gtcttattta ttacagttct ttattatact acagaccttt attattacag catttctatt
     3421 acattgtaaa gtcttattta ttacagttct ttattacact acagactttt attattacaa
     3481 tctcttattt attacagttc tttgctatac tacagacctt tattattaca gcatttctat
     3541 tacattgcaa agtcttattt attacagttc tttattatac tacagacttt tattattaca
     3601 gcatttctat tacattgcaa agtcttattt attacagttc tttattatac tacaaacctt
     3661 tattattaca acattttatt attttaactt ctttactata atatagtaat attttaatat
     3721 ctcaaaatca tatcaatcac ttttcagcat agtctaaaat acttccactt tctaaaatta
     3781 tctatcatac ctatactaat aatacttttt aaccttttta ttatacattt caattgtttc
     3841 taacaaccta tttatttcca aaactccaat atattttctc aattacattg tgttaatagc
     3901 ccctaaatcc tttcaaatta tttacaatac attccattaa ataatcttac tgctctataa
     3961 ttcttttttt ctttttaacc ctactataca ttatttacat catttttttc aatacaacat
     4021 tcgttattct ataacctttt tacttttact atatacttct tttctaatta caccttcaat
     4081 gttccacatc atattacttt agcacaacaa ttaataccta aaaataaccc tctaaatcct
     4141 ccaataatat aatcaattta actataataa taacctctca cactatccaa acaatatatt
     4201 ttcaaacatt acaaaaaaac atccaactat tacaatatag ctcatatccc tcctcccctt
     4261 tcaaatgcta tcattgactt acaagataaa tgaaagtgag gatgatatat atgcttaaag
     4321 taaaccaatt atgtaaatca tataaaacag gcagtaaaac atatcctgta ttaaaaaata
     4381 tttcttttga aatcaacaaa ggagaatttg tcgcaatcat gggttcatca ggaagtggaa
     4441 aaactactct tttaaattgt atttcatgtt ttatcccaat tgataatggg gaaataattc
     4501 ttggaaataa taatataaga aatttaaaag aaaaggaact ttcagaagtt agaaatcaac
     4561 aactaggatt tgtattccaa gacttcatgc tatttgatgg tcttagtgtc tttgaaaata
     4621 tatgtgttcc acaaattatc aaaggtagtc aagtcttaca aatggaaaac cgtgcaatta
     4681 atctatgtga gctatttggt attgaacata tcagaaaaaa ataccctgcc gaaatatctg
     4741 gtggagaaaa acagcgtaca gcagtagcaa gagcactcat gaacaaccca gatttaatat
     4801 tagcagatga accaactggt aaccttgata gtaagtcttg tcgtacagtc attgaatcat
     4861 ttttaaaagc aaagcaagaa ttagatgcta ctatactcat ggttacacac gatagctttg
     4921 cagcaagctt ctgtgaccga gttattgtgc ttaaagatgg aataatttat aaagaagttg
     4981 taaaatcaaa ttcaagacat aaattcctag atgaattact agaagtttta aaagaaatgg
     5041 gaggcgctca agatgacaat taataaatta tacagtaaac ttcgagccta taattggaag
     5101 aactatacaa ctttattctt ttgtataata ctttctgtgg tattagtaac ttcatatgct
     5161 ctaatttatt ttagcccaac aatacaaaac atacttccaa ctggtggaga tagcagaaaa
     5221 caggctacaa tgatattctc agttgctata ttaggatgcg ctgtctttac tacatacgct
     5281 tcttccctct ttttaaaatt taaaagcaag gaaattggta ttttcatggc tctaggaaca
     5341 gataagaaga aattaaaaaa acttctattt tcagagatat tgttaatttc aatagtatgc
     5401 tgttttttag gtcttatatt aagtattcct gtatcttttg gtatatggaa aatatttcaa
     5461 ttagtgatta ttgataccag agaaatgaca tatcattttg gaactcaagg attcatatat
     5521 ggatttatat ttagtgtatt tgtgacatta tgcatattta tactttctgt aaaatttatt
     5581 aatcgtacaa atataattga tatattaaat gaccagagaa tatctgaacc aatacaggat
     5641 gtaaaggact ggtatggtat attaggtata atttttatta tactcggtat ttttctagga
     5701 tatctcgtac cttcactaac tataaacaaa ttaaattata aactaccatc tatatggagc
     5761 tttacttatc tactctctct tattggaata tatatgatta tgacatacat agttgtacat
     5821 gctaaaagag gaaaacatcc agagaaatac tataaaaaca tcatatcaac tagcatgatg
     5881 agatttatgg gaagacaaac agtaaaaaac atgtgtgtta tttcattttt gattgcagga
     5941 gcattatttg ctgtattcta tgttcctaat atggttacag gtatctatga tactcttaaa
     6001 aataacccta tagattatac ttttacctac aatcaaagag ataaacaggt atcaaaaaaa
     6061 gatattgaac aattagcaga taaacacaat ataaaaattc aaaactatat ggaaattcct
     6121 tctatagaat taattgttga tggtgtagaa tcaatatatc ataaagatgg aactatcgaa
     6181 aaggtatata tgaaaaaaag ctcctatgat atgttcttta attccaaaga tttttccaag
     6241 ctaattggca aaccaataac tataaaaaat ggtgaatatc ttgctgttgt aaataaagga
     6301 aatgaaaatc aagattataa atataccaaa tttatatcaa gcccagtcac agaaaaagaa
     6361 atccccttta gatatgctgg aaaaataata tttaatggtt ctttttttca aaatagaagt
     6421 atgaacgcct atgtccttaa tgaggaggat tataaatcat ttactaaaga tttatccata
     6481 aaaaattaca ataattctat actatttaat gtagataaag atacctatgc ttttgccaat
     6541 gacttaaaga aagaaattat aaaaagaaca tctaaggaaa tgggcatgtt cagtggttat
     6601 gatgaatacg taaaaaaacg ttatgaatca actggaagaa aatattttat ggatgaagaa
     6661 tatccaagtg gtgaaggtca tttaaaacta gacccaaaca acaatcagtt gtatcttaat
     6721 tggaaatact atcctaactt taaaatttta caaagccaag atatgataaa aaacatggca
     6781 gtcttcttaa tgttattcat atatgtggca atcatatgtt ttacagcagt aggaatcatt
     6841 gcatatacaa ggggtgttac tatagctata aatcacaagc aggtctttat ggatttaaat
     6901 cgattaggag caaacaatga ttatataaag ttctgtatta gaaatcaatt aaagaaagta
     6961 ttttcatacc ctcttattgc aggaagtttt ttaatttatc tgtttaattt tatgattatg
     7021 ttaaataatg atggtagaat cgtcaatagt gaggtcaatg ctcttttgat aaacttaggt
     7081 tttataggga tttgtggggt ttatatgtac cttatatatc tattaactta taagaaattc
     7141 aaaaaaatta ttggtatttt ataataaaaa aggttattag atttttaaag taat
//
LOCUS       DAYAOO010000142         7185 bp    DNA     linear   BCT 12-OCT-2024
DEFINITION  TPA_asm: Clostridioides difficile isolate ST8-SSI-h139-18
            SAMN40601845-rid21577343.denovo.146, whole genome shotgun sequence.
ACCESSION   DAYAOO010000142 DAYAOO010000000
VERSION     DAYAOO010000142.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN40601845
            Sequence Read Archive: SRR28438827
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 7185)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7185)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-MAY-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-MAY-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002157583.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002157583.1
            Genome Coverage       :: 163x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/11/2024 16:19:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 4,038
            CDSs (total)                      :: 3,963
            Genes (coding)                    :: 3,930
            CDSs (with protein)               :: 3,930
            Genes (RNA)                       :: 75
            rRNAs                             :: 6, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 60
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 33
            CDSs (without protein)            :: 33
            Pseudo Genes (ambiguous residues) :: 0 of 33
            Pseudo Genes (frameshifted)       :: 7 of 33
            Pseudo Genes (incomplete)         :: 25 of 33
            Pseudo Genes (internal stop)      :: 11 of 33
            Pseudo Genes (multiple problems)  :: 8 of 33
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7185
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN40601845-rid21577343.denovo.146"
                     /isolate="ST8-SSI-h139-18"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Denmark"
                     /collection_date="2018"
                     /collected_by="Statens Serum Institute"
     gene            1..76
                     /locus_tag="ACGI5H_003693"
     tRNA            1..76
                     /locus_tag="ACGI5H_003693"
                     /product="tRNA-Phe"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:34..36,aa:Phe,seq:gaa)
     gene            83..156
                     /locus_tag="ACGI5H_003694"
     tRNA            83..156
                     /locus_tag="ACGI5H_003694"
                     /product="tRNA-Met"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:117..119,aa:Met,seq:cat)
     gene            171..247
                     /locus_tag="ACGI5H_003695"
     tRNA            171..247
                     /locus_tag="ACGI5H_003695"
                     /product="tRNA-Ile"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:205..207,aa:Ile,seq:cat)
     gene            265..341
                     /locus_tag="ACGI5H_003696"
     tRNA            265..341
                     /locus_tag="ACGI5H_003696"
                     /product="tRNA-His"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:299..301,aa:His,seq:gtg)
     gene            350..425
                     /locus_tag="ACGI5H_003697"
     tRNA            350..425
                     /locus_tag="ACGI5H_003697"
                     /product="tRNA-Lys"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:383..385,aa:Lys,seq:ttt)
     gene            433..506
                     /locus_tag="ACGI5H_003698"
     tRNA            433..506
                     /locus_tag="ACGI5H_003698"
                     /product="tRNA-Cys"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:465..467,aa:Cys,seq:gca)
     gene            514..590
                     /locus_tag="ACGI5H_003699"
     tRNA            514..590
                     /locus_tag="ACGI5H_003699"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:548..550,aa:Arg,seq:acg)
     gene            603..678
                     /locus_tag="ACGI5H_003700"
     tRNA            603..678
                     /locus_tag="ACGI5H_003700"
                     /product="tRNA-Val"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:636..638,aa:Val,seq:tac)
     gene            754..1167
                     /locus_tag="ACGI5H_003701"
     CDS             754..1167
                     /locus_tag="ACGI5H_003701"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009887782.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9699375.1"
                     /translation="MYIVIGNEIVDSEELKIIIDKNSEFKVEKDLSKSTKREDVIAYQ
                     LSIDLNYLDSLINEQCNLASLSDEEKFDEYMTLSDELALDLEELMPKYTIINARAYKL
                     DEVDGIVKIILAVAYADLGHLKLSDVVKRLSRQVD"
     gene            1476..4907
                     /locus_tag="ACGI5H_003702"
     CDS             1476..4907
                     /locus_tag="ACGI5H_003702"
                     /EC_number="6.4.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004736 - pyruvate carboxylase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0009374 - biotin binding [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0006090 - pyruvate metabolic process
                     [Evidence IEA];
                     GO_process: GO:0006094 - gluconeogenesis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate carboxylase"
                     /protein_id="HFG9699376.1"
                     /translation="MLKKFNKILVANRGEIAIRIFRACSELGIKSVGIYSKEDKYGLF
                     RTKADESYLIGEGKGPIDAYLDMDGIIDLAKRKKVDAIHPGYGFLAENAEFARKCEEN
                     GITFIGPSSKVMNMMGDKINSKKIAKEVNVQTIPGVEKAIRSTEEAKEVANKIGYPVM
                     IKASNGGGGRGMRIVHREEDLELEYETACSESRKAFGEDIIFIEKYIADPKHIEVQIL
                     GDNYGNIVHLYERDCSVQRRHQKIIEYAPAFSLDDKVRKEICEDAVKLSKHVGYSNAG
                     TLEFLVDANGGHYFIEMNTRVQVEHTVTEMVTGIDIVQSQILIAQGYSLDSEEINIKS
                     QDDVEIRGYSIQCRITTEDPKNKFMPDTGKIQVYRTGSGFGIRLDGGNGFTGANISPH
                     YDSLLVKTISWDRTFQGAINKTIRSIKELRVRGVKTNVGFLVNVLNNPIFSNGKCSTK
                     FIDENPDLFEITESKDRGTKLLQFIGDVIVNDNACKEKPLFDALHDPRMDKDGSKSEG
                     SKILFDKLGKSAYIEKIKNDKKLLLTDTTMRDAHQSLLATRIRTYDLLKAAKPTEKYQ
                     KDLFSLEMWGGATYDVAYRFLKESPWRRLQKLREEIPSIMFQMLLRASNGVGYKNYPD
                     NVIEEFTRESARQGIDVFRIFDSLNWVENMKPSINTALETGKIVEATMCYTGDILDKT
                     KTKYNLEYYIKMAQELESLGADIIAIKDMSGLLKPYSAYTLVKELKKNVKAPIHLHTH
                     DTSGNGVATCLMASEAGVDIIDAALESMAGLTSQPSLNAIVEALKNTERDTGIDLFGY
                     DELGKYYKDLRKVYNKFESDLTNSCAEIYNFEIPGGQYTNLKPQADSLGLVNRFDEVK
                     EKYKEANEVVGDIIKVTPSSKVVGDLAIFMTKNKLDKDNIIEEGKNLSFPDSVVDYCK
                     GMIGQPEGGIPKDLQEVVLKGEEAITVRPGSLLPAEDFDEIAKYLNEKYDINANIRNV
                     ISYALYPKVYEDYIKHLQHYNDISKLESDVFFYGLNKNEECEVEIEEGKVLTIRLVEI
                     GEVKENGFRTIGFELNGMVREVEIKDKNFSGKINNVEKADMNDPLQIGASIPGKVIKI
                     MVKEEDEVKANQPLIVIEAMKMETIIVAKTDGVIKSIKVKEDDMVEDKQLLMIMK"
     gene            5149..7077
                     /locus_tag="ACGI5H_003703"
     CDS             5149..7077
                     /locus_tag="ACGI5H_003703"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009904742.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003924 - GTPase activity [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor G"
                     /protein_id="HFG9699377.1"
                     /translation="MKVYDSKMLRNVAVLGHSGCGKTNLIETIAYTANTNKIPKLTDK
                     VNMTYSMGLIPIEYNDYKFNLLDTPGYFDFSGDVVSSLRASDAAIIVIDATAPIQVGT
                     EKSLELTESIPKIMFINKIDNEKARYKDAIAMLREKYNNKIVPMISPIYKDKNFVKLH
                     NVFENIDDLEGEFKEQAMSVKEALMELIAETDDQILDKYFNGEELTTEEIQKGIIIGI
                     QRGDIIPVICGSTINNIGTKEILDTISSYLEPIFTEESKPFRGLVFKTMVDPFVGKMS
                     YIKITEGVLSKDKDVFNINKNVKEKIANIYTLRNSELVEIEKAKAGDIVVITKVNSLK
                     TGDTISADKDAEALEKIDFPKPQIYYAVTPKNKGDEEKVASVLNKLVEEDPTLHWYRN
                     TETKQALLGGQGELHIKTIKNKMKDKFGVDVELNDLKVPYRETIKGTADVQGKHKKQS
                     GGHGQYGDVKIRFERCESDFEFTEEIFGGSVPKQYIPAVEKGLKDSMQKGILAGYPVT
                     NIKATLYDGSYHDVDSSEMAFKMAASAAFKKGMEEAHPILLEPIMKLKITVPEEYMGD
                     VMGDINKRRGKIFGMEPDDKGKQIIFAEAPQAETFKYAIDLRAMTQGRGYFEMELERY
                     GEVPSQFAEKIIGLATAK"
BASE COUNT         2925 a          835 c         1396 g         2029 t
ORIGIN      
        1 gcccagatag ctcagtcggt agagcagggg actgaaaatc cccgtgtcgg tggttcgatt
       61 ccgcctctgg gcaccaaaat gtggcggtat agcttagttg gctagagcgt tcggttcata
      121 cccgaaaggt cataggttcg actcctatta ccgctactga aatttaatgt gggccattag
      181 ctcagttggt tagagcgccc ggctcataac cggtaggtct ggggttcgag tccctgatgg
      241 cccaccacat taaattaact tatggtgggt atagctcagt tggttagagc gccagattgt
      301 ggctctggag gtcgtgagtt cgactctcat tatccacccc aacttatatg gtctattagc
      361 tcagtcggta gagcacctga cttttaatca gggtgtcccg cgttcgagtc gcggatagat
      421 caccaaaaag gcggcgacat agccaagtgg taaggcagtg gactgcaact ccttgatccc
      481 cagttcgaat ctgggtgtcg cctccaataa aatgcgctca tagctcaact ggatagagtg
      541 tctgactacg aatcagaagg ttaggggttc gagtcccttt gggcgcacca tatgaatagc
      601 gagggattat agctcagctg ggagagcacc tgccttacaa gcagggggtc acaggttcga
      661 gccctgttaa tcccaccagt gcaaacctct agtaaaacta ctagaggttt tatttttgat
      721 tgaaaaagtt tttatattta ggaggtaaaa aatttgtata tagtaatagg aaatgaaata
      781 gttgatagtg aagaacttaa aataattata gataaaaata gtgaatttaa agttgaaaaa
      841 gatttaagta aaagcacaaa aagagaagat gtaatagcat atcagttaag tatagattta
      901 aattacctag attctcttat aaatgagcaa tgtaatttag ccagtctatc tgatgaagag
      961 aaatttgatg aatatatgac tttgtctgat gaacttgcac tggatttaga agagttaatg
     1021 ccaaaatata caataataaa tgctagagca tataaattag acgaggtaga tggaattgta
     1081 aaaataatac tagctgtagc gtatgcagat ttagggcact tgaaactttc tgatgtagta
     1141 aagaggctat ctagacaagt agattaggat atgaatatga actatattaa aaaaatgtat
     1201 aaaatcttac gtaaagatga aaataattat gtaaacatag aaaaaaacag tataaaatca
     1261 agtcaattgt agaaattttc acataaattc atctgaaatt ctataaaaaa tgccttaatt
     1321 ttaatgaggt aaatcgagtt tacacagtct aaaaattact tatatttata aatttatctt
     1381 attaattaag gaactttctt aaacatcttc aaaaataaag tattttagtc tataatcttt
     1441 aatattacac aaacaataaa ggagaagaat agagtatgct taaaaagttt aataaaatac
     1501 tagtggctaa tagaggcgaa atagctataa gaatatttag agcctgttca gaattgggga
     1561 taaaaagtgt tggtatatac agtaaggaag ataagtatgg attgtttaga acaaaagcgg
     1621 atgaatcata tttgatagga gaaggtaaag ggccaataga tgcatattta gatatggatg
     1681 gaataataga cctagcaaag agaaaaaaag ttgatgctat acatccagga tatggttttc
     1741 tagcggagaa tgcagaattt gctcgtaaat gtgaagagaa tggaattact tttataggac
     1801 catcatctaa ggtaatgaat atgatggggg ataagattaa ctctaaaaaa atcgcaaaag
     1861 aagttaatgt tcaaactata ccaggagtag aaaaagcaat aagaagtact gaagaagcaa
     1921 aggaagttgc aaacaaaata ggatatcctg ttatgataaa agcatctaat ggcggtggcg
     1981 gtagaggtat gagaattgta catcgcgaag aagacttaga gcttgaatat gaaactgctt
     2041 gtagtgaatc aagaaaagct tttggagaag atattatatt tatagaaaaa tatatagctg
     2101 atccaaaaca tatagaagtt caaatattag gtgataatta tggaaatata gttcacttat
     2161 atgaaagaga ttgttcagtt caaagaagac atcaaaaaat aatagaatat gcaccagctt
     2221 tttcattaga tgataaagta agaaaagaga tatgtgaaga tgcagttaag ttatcaaaac
     2281 atgtgggtta ttctaatgcg ggaacattag aatttttagt agatgcaaat ggtgggcatt
     2341 attttataga gatgaacaca agagtacagg ttgaacatac tgtaacagag atggttacag
     2401 gaatagatat agttcaaagt caaatactaa tagcccaagg ttacagctta gatagtgaag
     2461 aaattaatat aaaatcacaa gatgatgtgg aaataagagg ttactctatc caatgtagaa
     2521 taactacaga agaccctaag aataaattca tgcctgatac aggtaaaatt caagtttata
     2581 gaactggttc aggatttggt ataagactag atggaggaaa tggatttaca ggggcaaaca
     2641 taagtcctca ttatgatagt ttattggtta agacaatatc ttgggataga acattccaag
     2701 gagcaataaa taaaactata agatctataa aagaacttag agttagaggt gttaaaacta
     2761 atgtaggatt cctagttaat gttttaaata atcctatatt ctcaaatggt aaatgtagta
     2821 ctaagtttat agatgaaaat ccagatttat ttgaaataac agaaagtaaa gacagaggaa
     2881 caaaattact tcaatttata ggagatgtaa ttgtaaatga taatgcttgt aaagaaaaac
     2941 cattatttga tgcattacat gacccaagaa tggataagga tggttcaaaa tcagaaggaa
     3001 gtaaaatact tttcgataag ttaggtaaat ctgcatatat agaaaagata aaaaatgata
     3061 agaaattact attaacagat acaacaatga gagatgcaca tcaatcatta ttagcaacaa
     3121 gaataagaac atatgactta ttaaaagctg ctaagccaac agaaaaatat caaaaggatt
     3181 tattctcact tgaaatgtgg ggaggagcta cttatgatgt tgcatataga tttttaaaag
     3241 aatctccttg gcgtagatta caaaagctaa gagaagaaat accaagcata atgttccaaa
     3301 tgttgcttag agcatcaaat ggagttggat ataaaaacta tccagataat gtaatagaag
     3361 aatttacaag agaatctgct agacaaggta tagatgtatt tagaatattt gattcattaa
     3421 actgggttga aaatatgaaa ccatctatta atacagcttt agaaactgga aaaattgttg
     3481 aagcaactat gtgttataca ggtgatatac tagataagac taaaactaaa tacaatctag
     3541 aatattatat taaaatggca caagaattag aaagcttggg agcagatata atagcaataa
     3601 aagatatgtc aggtcttctt aaaccatatt cagcttacac attagttaaa gagttaaaga
     3661 aaaatgtaaa agcaccaata catttacaca ctcatgatac aagtggaaat ggtgtagcaa
     3721 cttgtttaat ggcgtcagaa gctggagtag acataattga tgctgcatta gaatctatgg
     3781 caggacttac aagtcagcca tcacttaatg ctatagtaga ggcacttaag aatacagaga
     3841 gagatacagg aatagattta tttggatatg atgagttagg aaaatattat aaggatttaa
     3901 gaaaagttta taataaattt gaaagtgatt taactaattc ttgtgcagaa atatataatt
     3961 ttgaaatacc aggaggccaa tatacaaact taaaacctca agctgatagt ttaggattag
     4021 ttaatagatt tgatgaagtt aaagaaaaat ataaagaagc taatgaagtt gtaggagata
     4081 taataaaagt aactccatct tcaaaagttg taggagactt agctatcttt atgactaaaa
     4141 ataaattaga taaagacaat ataatagaag aaggtaaaaa tttatcattc ccagattctg
     4201 ttgtggatta ctgtaaaggt atgattggtc aaccagaagg tggaatacca aaagatttac
     4261 aagaggtagt tctaaaaggt gaagaagcta taacagtaag accaggttca ttattaccag
     4321 cagaagattt tgatgaaata gctaaatatc taaatgaaaa gtatgatata aatgctaata
     4381 taagaaatgt tataagttat gctttatatc caaaagtata tgaagattat atcaaacatc
     4441 tacaacatta taatgatata tctaaacttg aaagtgatgt attcttctat ggattaaata
     4501 aaaatgaaga atgtgaagta gaaatagaag aaggtaaggt attaacaata agattagttg
     4561 aaattggtga agttaaggaa aatggattta gaactatagg atttgagtta aatggaatgg
     4621 ttagagaagt agaaataaaa gataagaatt tctctggaaa aattaataat gttgaaaaag
     4681 ctgatatgaa tgaccctctt caaattggag caagcatacc aggaaaagtt ataaaaataa
     4741 tggttaaaga agaagatgaa gtaaaagcaa atcaaccatt aatcgttata gaggctatga
     4801 agatggaaac tataatagtt gctaagactg atggagtaat taagtcaatc aaagtaaaag
     4861 aagatgatat ggttgaagat aaacaattat taatgataat gaagtaattt aattaaaata
     4921 aattaaaaag cactctgaaa tgtttaataa aaaatgtttt agagtgtttt tatttatttt
     4981 aattaaatat ttgttaaaaa aaagaggaca attacctcca gatgtagaaa taaagctagt
     5041 aaggaaaatg ttatctaaaa attctaaata tagtaaatat tttccataat atttcttagg
     5101 aaataacagc aaagataaaa tacataaatt taaaaggtgg gtgcttatat gaaggtttat
     5161 gatagtaaaa tgttgagaaa tgtagcggta ttaggacata gcggatgtgg aaaaacaaat
     5221 ctaatcgaaa ctatagctta cacagcaaac actaataaga tacctaaatt aacagacaag
     5281 gtaaatatga cttatagcat gggattaata cctatagagt ataatgatta taagtttaac
     5341 ttattggata ccccaggata ttttgacttt agcggagacg ttgtgtcatc tcttagagca
     5401 agtgatgcag caataatagt aatagatgca acagcgccta ttcaagttgg tacagagaaa
     5461 tcattagaac taactgagag tattcctaag ataatgttta taaataaaat agataatgaa
     5521 aaggcaagat acaaagatgc aatagcaatg ttaagagaaa aatacaataa taagatagtt
     5581 cctatgataa gtcctatata caaagataaa aactttgtaa agttacataa tgtttttgaa
     5641 aacatagatg atttagaagg tgaatttaag gaacaagcta tgagtgttaa agaagcatta
     5701 atggaactta tagcagaaac tgatgaccaa atattagata aatattttaa tggagaagaa
     5761 ctaactacag aagagataca aaaaggtatt attataggta tacaaagagg tgatattata
     5821 cctgtaatat gtggttcaac tataaataat ataggcacaa aggaaatatt agatacaata
     5881 tcaagttatt tagaacctat ctttacagag gaaagcaaac catttagggg attagtattt
     5941 aaaactatgg ttgacccatt tgttggaaag atgtcatata taaaaattac tgagggtgta
     6001 ctttctaagg ataaagatgt ttttaatata aataaaaatg taaaagaaaa aatagctaat
     6061 atatatacat tgagaaatag tgaattagta gaaatagaaa aagctaaagc tggtgatata
     6121 gtagttataa ctaaagttaa ttctctaaaa acaggagaca ctatatctgc agataaagat
     6181 gcagaagctt tagaaaagat agattttcct aaaccacaaa tatattatgc agtaactcct
     6241 aagaataaag gtgatgaaga aaaagtagca tctgtattaa ataaactagt agaagaggac
     6301 cctacattac attggtatag aaatacagag acaaaacaag cacttttagg aggtcaagga
     6361 gaacttcata taaaaacaat taaaaataaa atgaaagata agtttggtgt tgatgttgaa
     6421 ttgaatgacc ttaaagttcc ttatagagaa actataaaag gaacagctga tgtacaagga
     6481 aaacataaaa agcaatcagg tggtcatggt caatatggag acgtaaaaat aagatttgaa
     6541 agatgtgaat ctgattttga atttacagaa gaaatatttg gtggttctgt accaaaacaa
     6601 tatataccag cagttgaaaa aggtttaaaa gactctatgc aaaaaggtat attagcagga
     6661 tatcctgtta caaacataaa agctacgctt tatgatggtt cataccatga tgtagactct
     6721 tctgaaatgg cctttaaaat ggcagcaagt gcagccttta aaaaaggtat ggaagaagca
     6781 cacccaatac tactagaacc tataatgaaa cttaagataa ctgttccaga agaatatatg
     6841 ggagatgtca tgggtgatat aaataagaga agaggaaaaa tatttggaat ggaaccagat
     6901 gacaaaggga aacaaataat atttgcagaa gctccacaag cagagacatt taaatatgca
     6961 atagatttaa gagcaatgac acaaggtaga ggatactttg aaatggaatt agagagatat
     7021 ggagaggttc catcacagtt tgcagaaaaa ataattgggt tagctactgc aaagtaatga
     7081 acaaaataaa tagaaaaata attaatatat attattaaaa atatttttag ggttttaact
     7141 aggtataggt ttatgttagg taaacttata cctagttttt ataca
//
LOCUS       DAYAOO010000143         7151 bp    DNA     linear   BCT 12-OCT-2024
DEFINITION  TPA_asm: Clostridioides difficile isolate ST8-SSI-h139-18
            SAMN40601845-rid21577343.denovo.147, whole genome shotgun sequence.
ACCESSION   DAYAOO010000143 DAYAOO010000000
VERSION     DAYAOO010000143.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN40601845
            Sequence Read Archive: SRR28438827
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 7151)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7151)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-MAY-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-MAY-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002157583.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002157583.1
            Genome Coverage       :: 163x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/11/2024 16:19:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 4,038
            CDSs (total)                      :: 3,963
            Genes (coding)                    :: 3,930
            CDSs (with protein)               :: 3,930
            Genes (RNA)                       :: 75
            rRNAs                             :: 6, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 60
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 33
            CDSs (without protein)            :: 33
            Pseudo Genes (ambiguous residues) :: 0 of 33
            Pseudo Genes (frameshifted)       :: 7 of 33
            Pseudo Genes (incomplete)         :: 25 of 33
            Pseudo Genes (internal stop)      :: 11 of 33
            Pseudo Genes (multiple problems)  :: 8 of 33
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7151
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN40601845-rid21577343.denovo.147"
                     /isolate="ST8-SSI-h139-18"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Denmark"
                     /collection_date="2018"
                     /collected_by="Statens Serum Institute"
     gene            485..976
                     /gene="infC"
                     /locus_tag="ACGI5H_003704"
     CDS             485..976
                     /gene="infC"
                     /locus_tag="ACGI5H_003704"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015526092.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003743 - translation initiation factor
                     activity [Evidence IEA];
                     GO_process: GO:0006413 - translational initiation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="translation initiation factor IF-3"
                     /protein_id="HFG9699378.1"
                     /translation="MNEQIKDKEIRVLSPTGEQLGVMPTKEAQAMANSKNLDLVQISP
                     NANPPVCKIMDYGKFRYEQARKEKEAKKKQKTIVVKEVRLRPGIEQNDLNTKANNAIK
                     FLKKGDKVKVELRFRGRELGHKDIGKEVMLKFLDIIKEFGEPTKAPAFEGNNMVVIID
                     PKK"
     gene            1004..1198
                     /gene="rpmI"
                     /locus_tag="ACGI5H_003705"
     CDS             1004..1198
                     /gene="rpmI"
                     /locus_tag="ACGI5H_003705"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L35"
                     /protein_id="HFG9699379.1"
                     /translation="MPKMKTHRGAAKRLKKTGTGKLKRAKAFKKHILTKKSAKTKMNL
                     RKSTLVSDGDAKRIAQLLPY"
     gene            1254..1610
                     /gene="rplT"
                     /locus_tag="ACGI5H_003706"
     CDS             1254..1610
                     /gene="rplT"
                     /locus_tag="ACGI5H_003706"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423569.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0000315 - organellar large ribosomal
                     subunit [Evidence IEA];
                     GO_component: GO:0022625 - cytosolic large ribosomal
                     subunit [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L20"
                     /protein_id="HFG9699380.1"
                     /translation="MARVKKAMNARKKHKKILKLAKGFRGSRSKLYRPANTFVMKALK
                     NAYIGRKLKKRDFRKLWIQRINAAARMNGISYSRLMNGLKLSGVEVNRKMLSEMAIQD
                     PEGFAKLAEVAKAKLA"
     gene            1920..2465
                     /locus_tag="ACGI5H_003707"
     CDS             1920..2465
                     /locus_tag="ACGI5H_003707"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895726.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9699381.1"
                     /translation="MNEKLMDCFVNPIKCKLLIEIFSNNRTTAKQLGEKFQDISKATL
                     YRYLNKMLKDDIIKVVEENKIRGTVEKVYAMKLDIADDVNKIIDENSGEEYAQLFTQY
                     MMGFLREFYEYAERKEKDILKDGSGFSVCPVYASIDEIVEVSKKIASILEPLRNNSHE
                     EGRRMHSIGVIITPPKKDEGK"
     gene            2900..4825
                     /locus_tag="ACGI5H_003708"
     CDS             2900..4825
                     /locus_tag="ACGI5H_003708"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888496.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="metallophosphoesterase"
                     /protein_id="HFG9699382.1"
                     /translation="MKIKFVIMPLVIFLMVLFVGCQSTKDTEVKAKDTEIKILGTGDL
                     HSILTDSMVSYVNEEREKNKNLLMVDAGDFYGTQSREMWEWSSGKKLINIKRNGRAEY
                     DDIIKSSKDEVPIVKDMAKLKYDAVVLGDNEFVSNDKQSLDKLVSDFKNNNMPLVSAN
                     IYEQSGENYVQPYVMKNIKTDEGNVKVGILGLTIKEVGETLGLEDFEKDKKARELGEQ
                     ADYKGKLYANDLVEDAKKWIKVMEKESPDIIVAVVHSGEEPKTDRNPGNRIKELATTV
                     DGIDAIVAGHTHEKIDEHKYKNKSGDEVIVTQPGWHGDRVSEINFKLNKENGKWDIKE
                     KSSKLKIIDKEVSIVATADLHSHFSDKLTVDLVNERSNPIEPVVVDAGDFLDPQTDEM
                     TQWYKEWKSIRDNNSDKTISRCPMVMDMNQGMYDAVVLGNHEFVSEKDEFWSDERLLD
                     AVIEDFEQVAISVLSANIYRQSGKNYVKPYIIKDVETSEGNVKVGILGLTIKEVGKGL
                     KNVNLQEQFQYKDKLYANDLVEDAKKWVKVMKKKKPDIIVAVVHSGEEPKNPKHPGNR
                     IKELATTVDGIDAIVASHTHEKIDEHEYKNKSGEKVIVTQPGEHGKYYSKITFKVNKE
                     KGSWTINDKFSKTIEVE"
     gene            5226..7130
                     /locus_tag="ACGI5H_003709"
     CDS             5226..7130
                     /locus_tag="ACGI5H_003709"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902100.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="metallophosphoesterase"
                     /protein_id="HFG9699383.1"
                     /translation="MKIKFIIVASIIFLIVLLVGCQSTKDTEINVLATSDLHSIIPDN
                     LISYVEEERKYDENLLMVDAGDFFDMQSGEMNKWFTGQKLVRFKDGIPEYKKIAEPRE
                     GEVPLAKKMAKLKYDAVTFGNHEFVSNDKQSLDKLVSDFKNNNIPLVSANVYEQSGEN
                     YVKPYVMKNINTDKGTVKVGILGLTIKEVGERSRFKSFEQDKKARELGEQPQYKGKLY
                     ANDLVEDANKWVNVMEKKEKPDIIVAIVHSGEEPKNPKNPGNRIKELATTVEGIDAIV
                     AGHTHEKIEQHTYKNNSGEEVIVTQPGAHGNSISKINFKLDKKNDKWFIKDKYSELKV
                     FGKEVNIITTSGLNPKFSDEMAVNLFNERDRDVQPIFIDTGDFLNTNTKEMTKWAKEW
                     QYNENKGIYKKINEWPIVYLGYDAVVLGSHEFTEDKETFEEKKSTLDYIIENFEEMKI
                     PVLSANIYDESGENYVKPYIIHNVETREGNIKVGVLGLTTTDKDEEDLSNSSLSKDSK
                     TSKIPEETGKLYTNNLVKDASEWVKVMQKESPDVIVAVVHSDNNSTLKNPSSEVKKLA
                     MSVDGIDAIVVGHTKNKVEEHIYKNKSGDEVIVTQSGEDCYSKISLELRKENGKWNII
                     NKYSKAIKMK"
BASE COUNT         3011 a          714 c         1354 g         2072 t
ORIGIN      
        1 tagtatatta gagtacaata tagaatttgt tatgtagtat agtagtatat tagaatacaa
       61 tatagaattt gttgggtagt atagtgttat attagaatac aatataggat ttgttatgta
      121 gaatatatag agtcatgtag aatatacata tataaaagga ttttgggtat aaatttaaaa
      181 attaatagca aaatgagtag tatagacata taattagtag taggaagtaa ttaaattttt
      241 cctaaacaaa aaaaatagtt gcaaataatt tgattaagtg atatagtaaa taaggtaaga
      301 ataaaacaaa gaagaagtcc gcttctcacc ttacgccgga ggttagtaag gtaaatataa
      361 gttaaagctt aattttaatt taagtttgtt taaatttggt aacttatatt gcggatgatt
      421 acgtcatccg ctttttattt tataaaaatt ttggaggtgt cctacaatta gcaaagaatt
      481 agcaatcaat gaacaaataa aagataagga aataagagtc ctttcaccaa caggtgaaca
      541 acttggagta atgcctacta aagaagctca agcaatggct aatagcaaaa acttagattt
      601 ggttcaaatc tcgccgaatg caaatccacc agtatgtaag ataatggatt atggaaagtt
      661 tagatatgag caagcgagaa aagagaaaga agctaagaaa aaacaaaaaa ctatagttgt
      721 aaaagaagta agacttagac caggtattga acaaaatgat ttaaatacga aagctaataa
      781 tgctataaag ttccttaaaa aaggggataa agtcaaagtt gaacttagat ttagaggaag
      841 agaattagga cataaagaca taggtaaaga agttatgctt aagtttttag atataataaa
      901 agagtttgga gaaccaacaa aagcccctgc atttgagggt aataatatgg ttgtaattat
      961 agatccaaaa aaatagatga ttaactgaga ggaggaattt gtcatgccta aaatgaaaac
     1021 tcatagaggt gcagcaaaga gattaaagaa aacaggaact ggaaagttaa agagagctaa
     1081 agcttttaaa aaacatatat taactaaaaa atctgcaaaa actaaaatga acttaagaaa
     1141 atcaacttta gtaagtgatg gagatgctaa gagaatagca caattattac catactaaga
     1201 tacagattgt aaataataac tatagaagag ggatataaaa ggaggtcata acgatggcaa
     1261 gagttaaaaa agctatgaac gctcgtaaaa agcataagaa aatattaaaa cttgcaaaag
     1321 gattcagagg atctagaagc aaattatata gaccagcaaa tacattcgta atgaaagcat
     1381 taaaaaatgc ttatatagga agaaagttaa agaagagaga cttcagaaaa ctttggatac
     1441 aaagaataaa tgcagctgct agaatgaatg gaatatctta ttcaagatta atgaatggat
     1501 taaaattatc tggtgttgaa gttaacagaa aaatgttatc tgaaatggct atacaagacc
     1561 cagaaggatt tgcaaaatta gcagaagttg ctaaagcaaa attagcttag tattgaatca
     1621 tgagatgtaa agtctttgag ttatataaat aattcaagga cttttttatt ttttgaaaaa
     1681 tacttattag tgtcatgtac aaccaatttt ataatgataa ataaaataag caatacaata
     1741 gaattttatg agatttatta taagaattgt tacaattatt tatgatagct ataaaaagtc
     1801 atagtaaaaa tgatattgat gtatgttgat atatgtataa agtttccaat caatcttgaa
     1861 ttaatattat caacatgata atattatctt attaataata taaataaggg ggacataata
     1921 tgaatgaaaa actaatggat tgttttgtaa acccaattaa atgcaagtta ttgattgaaa
     1981 ttttttcaaa taatcgaact acagctaaac aattaggaga aaaatttcaa gatatatcaa
     2041 aggcaacact ttatcgttac cttaataaaa tgttgaaaga tgatattata aaagtggttg
     2101 aagaaaataa aataagggga actgttgaaa aagtatatgc tatgaagtta gatatagctg
     2161 atgatgtgaa caaaattata gatgagaact ctggagaaga atatgctcaa ctgtttactc
     2221 aatatatgat gggattttta agagaatttt atgaatacgc tgaaagaaag gaaaaggata
     2281 tcctaaaaga tggttcagga ttttctgtct gtccagtata tgctagtatt gatgagatag
     2341 ttgaagtgag taaaaaaatt gctagtatac tagaacctct aagaaataac tcacatgaag
     2401 aaggtagaag aatgcattct ataggagtga taattactcc acctaaaaag gatgaaggga
     2461 aataaatctg atttacatgg ggtagagcca atttatacag ggaatcgttt tatgatttac
     2521 atatgtatcc agagcaaagt atctctgctt ggattgtact tcattgtacc atttcatcca
     2581 atgacttgga gtggtacaat gaagtttttt aatttttcat attaatgcta aagaaatgaa
     2641 ctttagacca catatgcaat taggttgcat tatacaatta gaccacatat acaaaataaa
     2701 aatcagtatt tttatagcag ataaattgac tgtcattctt cttaaaaatc atctattagt
     2761 tattgttagc atattgaaag aaattatagt aatctattga ataaatgaat attgcctata
     2821 atcatataaa ctgctatagt ttaaaataaa gcaggacgtt aaattttata gtaatctaaa
     2881 aatttaagag ggggatttta tgaaaataaa atttgttatt atgccattgg tgatattttt
     2941 aatggtatta tttgtggggt gtcaaagtac aaaagataca gaagttaaag caaaagatac
     3001 agaaattaaa atattaggga caggtgattt acattcaatt ttgacagact ctatggtttc
     3061 gtatgtaaat gaggaaaggg aaaagaataa aaatctgctt atggtagatg cgggagattt
     3121 ctatggtaca caaagtagag aaatgtggga atggtcttct ggaaaaaagt taattaatat
     3181 taaaagaaat ggtagagcag agtatgatga cataattaag agtagtaaag atgaagtacc
     3241 tatagttaaa gatatggcaa agttgaaata tgatgctgta gttttgggag ataatgaatt
     3301 tgtttcaaat gataagcaaa gtcttgataa actggtttct gattttaaaa ataataatat
     3361 gccattggta tcagcaaata tatatgaaca atctggagaa aattatgtac aaccatatgt
     3421 aatgaaaaat attaagacag atgagggcaa tgtaaaagtt ggaatactag gtcttactat
     3481 aaaagaagta ggggaaaccc ttggtcttga ggattttgaa aaggataaaa aagctagaga
     3541 gcttggagaa caagctgatt acaaaggaaa attatatgca aatgatttag tagaagatgc
     3601 aaaaaaatgg ataaaagtta tggaaaaaga aagtccagac ataatagttg cagttgtaca
     3661 ctcaggggaa gaacctaaaa cagatagaaa tccaggaaat agaataaaag agttagcaac
     3721 tacagtggat ggaatagatg caattgtagc tggtcatact catgaaaaaa tagatgaaca
     3781 caaatataaa aataaatctg gagatgaagt aattgttaca caaccaggtt ggcatggaga
     3841 tagagtatca gagattaatt tcaaactaaa taaagagaat ggaaagtggg acataaagga
     3901 aaagtctagt aaattaaaaa taattgataa agaagtaagt atagttgcta ctgcagattt
     3961 acattcacat ttctctgata aattaacagt tgaccttgtt aatgaacgaa gtaacccaat
     4021 tgaacctgtt gtagtagatg caggcgactt cttagaccct caaacagatg aaatgactca
     4081 atggtataaa gagtggaaaa gtataagaga taataatagt gataaaacga ttagtagatg
     4141 cccaatggtc atggatatga atcagggaat gtatgatgca gtagtacttg gaaatcatga
     4201 atttgtatct gaaaaagatg aattttggtc agatgaacgc cttttagatg ctgttataga
     4261 ggattttgaa caggtggcaa tttctgtgtt atcggcaaat atatataggc aatctggtaa
     4321 aaattatgtt aaaccatata ttataaaaga tgtggagacg agtgaaggta atgtaaaagt
     4381 aggaatattg ggacttacta taaaagaagt aggtaaaggt cttaaaaatg taaacttaca
     4441 agagcaattt caatataagg ataaattgta tgcaaatgat ttagtggaag atgcaaagaa
     4501 atgggtaaaa gttatgaaaa agaaaaaacc agatataata gttgcagttg tacattcagg
     4561 agaagaacca aaaaatccaa aacatccagg aaatagaata aaagaactag caactacagt
     4621 agatggtatt gatgcaattg ttgctagtca tactcatgaa aaaatagatg agcatgaata
     4681 taaaaataag tctggagaaa aagttatagt gacacaacca ggtgagcatg gtaaatatta
     4741 ttctaaaatt acctttaaag taaataaaga aaagggttcg tggactatta atgataaatt
     4801 cagtaaaaca attgaggttg aataacttta taaaatttat agataaagta aattatctga
     4861 tattggcatg atatataaga taaagtttct aatattagta taatgcataa tgtgaaatat
     4921 tttaataata agagaataaa caagacaaat aaaaatattt taacatgtaa gatatagtat
     4981 gaactattat actaatgctt actttataat ttgaacatgt tagaataagt cttatttgaa
     5041 aattttagtg tactagagta agtattattt tactagtaaa aaatattgag aactatatgt
     5101 agatttgctt aaaaaggaat ttacatatag ttcttttcgt ataataaata gtacaatctt
     5161 atatggtaaa gataaagtgt gatattaaat tttattatca tccaaaatct aaggaggagt
     5221 ctcttatgaa aataaaattt attatagtag catcaataat atttttaata gtattacttg
     5281 tggggtgtca aagtactaaa gacacagaaa tcaatgtact cgccacaagt gatttacatt
     5341 caattattcc agataattta atttcctatg tagaagagga gagaaaatat gatgagaatc
     5401 tacttatggt agatgcagga gatttttttg acatgcaaag tggtgagatg aataagtggt
     5461 ttactggtca aaaattagta agatttaaag atgggatacc agagtacaaa aaaatagctg
     5521 aaccacgtga aggagaagtt ccattggcta aaaaaatggc aaagctgaag tatgatgcag
     5581 ttacatttgg gaatcatgaa tttgtatcta atgacaagca gagccttgat aaattggttt
     5641 ctgattttaa aaataacaat ataccattag tatcagcaaa cgtatatgaa caatctggag
     5701 aaaactacgt aaagccatat gtaatgaaaa atataaatac tgacaaggga actgtaaagg
     5761 ttggtatact tggtctgact ataaaagaag taggggaacg ttcaaggttt aaaagttttg
     5821 aacaagataa aaaggctaga gaacttgggg aacaacctca atacaaaggg aaattatatg
     5881 caaatgattt agtagaagat gcaaataagt gggtaaatgt tatggaaaaa aaagaaaagc
     5941 cagatataat agttgccatt gtacattcag gtgaagagcc aaaaaatcct aaaaatccag
     6001 gaaatagaat aaaagaacta gcaacaactg tagagggaat agatgctatt gtagcaggtc
     6061 atacacatga aaaaatagaa cagcatacat ataaaaataa ttctggtgaa gaagtaatag
     6121 taacacagcc tggagctcat ggtaatagta tatcaaagat taattttaag ttggataaga
     6181 agaatgataa gtggtttata aaagacaaat atagtgaatt aaaggttttt ggaaaggaag
     6241 taaatataat tacaacttct ggtctgaatc caaaattttc agatgaaatg gcagttaatt
     6301 tgtttaatga aagagataga gatgttcaac ctatctttat agatactgga gattttttaa
     6361 atactaatac aaaagaaatg actaagtggg ctaaagagtg gcaatacaat gaaaataaag
     6421 gcatctataa aaaaataaat gaatggccaa ttgtatatct tggttatgat gctgtagtac
     6481 ttggtagcca tgaatttaca gaggataaag agacttttga ggaaaaaaaa tctacattgg
     6541 attatattat agaaaacttt gaagaaatga agataccagt attatcagct aatatatatg
     6601 atgaatctgg agaaaattat gtaaaacctt atataattca taatgtagaa actagggaag
     6661 gaaatataaa ggttggagta ttaggtctta ctactactga taaggatgaa gaagacttaa
     6721 gtaactcaag cttaagcaaa gactcaaaga cttcgaaaat tcctgaagaa acaggaaagt
     6781 tatatactaa taatctagta aaagatgcaa gcgaatgggt aaaagttatg caaaaggaaa
     6841 gtcctgatgt gattgttgca gttgtacatt cagataataa tagtactcta aaaaatccaa
     6901 gtagtgaagt caaaaaactt gcaatgtcag tagatggaat agatgctatt gttgtaggtc
     6961 atacgaaaaa taaggtagaa gaacatattt acaaaaataa gtctggggat gaggttatag
     7021 taacacaatc tggagaagat tgttattcaa aaataagtct tgaactaaga aaagaaaatg
     7081 gcaagtggaa tatcataaac aaatatagta aagcaataaa aatgaagtga atttattgat
     7141 atataaacca t
//
LOCUS       DAYAOO010000144         7129 bp    DNA     linear   BCT 12-OCT-2024
DEFINITION  TPA_asm: Clostridioides difficile isolate ST8-SSI-h139-18
            SAMN40601845-rid21577343.denovo.148, whole genome shotgun sequence.
ACCESSION   DAYAOO010000144 DAYAOO010000000
VERSION     DAYAOO010000144.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN40601845
            Sequence Read Archive: SRR28438827
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 7129)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7129)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-MAY-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-MAY-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002157583.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002157583.1
            Genome Coverage       :: 163x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/11/2024 16:19:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 4,038
            CDSs (total)                      :: 3,963
            Genes (coding)                    :: 3,930
            CDSs (with protein)               :: 3,930
            Genes (RNA)                       :: 75
            rRNAs                             :: 6, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 60
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 33
            CDSs (without protein)            :: 33
            Pseudo Genes (ambiguous residues) :: 0 of 33
            Pseudo Genes (frameshifted)       :: 7 of 33
            Pseudo Genes (incomplete)         :: 25 of 33
            Pseudo Genes (internal stop)      :: 11 of 33
            Pseudo Genes (multiple problems)  :: 8 of 33
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7129
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN40601845-rid21577343.denovo.148"
                     /isolate="ST8-SSI-h139-18"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Denmark"
                     /collection_date="2018"
                     /collected_by="Statens Serum Institute"
     gene            18..869
                     /locus_tag="ACGI5H_003710"
     CDS             18..869
                     /locus_tag="ACGI5H_003710"
                     /EC_number="2.8.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902555.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016783 - sulfurtransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sulfurtransferase"
                     /protein_id="HFG9699384.1"
                     /translation="MKNIISAKELISKLEKNDNLVVIDCRFDLINRTYGIDSYKKGHI
                     KGSFILDIDKDLSSPTKEHGGKNPLQDPLILKEKLEKMGVDNDTTIVTYDDGDLNGAC
                     RLFFQLKHLGLKNVYVLDGGITSFVKEGGELEEKVNIPSCTGKEIRPNINNDLVVPME
                     YVKSKLYKKDTVIIDCRANERYQGLVEPAYSKAGHIPSAKNYFCKDLIKSDFENGSLK
                     DIEFLKKFFKDLNNYDEVILSCGSGISACVNSLALRELDIPHKIYIGSFSDWISYDDN
                     EIKTGQE"
     gene            complement(1002..2615)
                     /gene="ggt"
                     /locus_tag="ACGI5H_003711"
     CDS             complement(1002..2615)
                     /gene="ggt"
                     /locus_tag="ACGI5H_003711"
                     /EC_number="2.3.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728540.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0036374 - glutathione hydrolase activity
                     [Evidence IEA];
                     GO_process: GO:0006750 - glutathione biosynthetic process
                     [Evidence IEA];
                     GO_process: GO:0006751 - glutathione catabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="gamma-glutamyltransferase"
                     /protein_id="HFG9699385.1"
                     /translation="MKFNAYQHKYSSIRNVVYAKNGAVATSTPLASQAGLEILKKGGN
                     AVDAAVATAATLAVVEPTSNGIGGDAYALVWIEEEKRLYGLNSSGFAPENMELKNYNN
                     MKEMPKYGFGAVTVPGIPAAWSELNKKYGKLSLMECLSPAINYAREGYVVSPNVAKVW
                     KKSYELYEKELIGEEFKPWFDTFSKDGKAPEAGDIFICEEQASTLEEIANTQAESFYR
                     GRLADKIDEYSKKFNGAIRKSDLECFYPTWVEPISTEYKGYKIFEIPPNGHGITVLMA
                     LNILKELELEGNIENVEDIHKIIESLKLAFADSKTYVTDIEHMKVKIQELLSQEYAKK
                     RSLLIDNKEALYPTAGEPYCGGTVYLCTADKDGNMVSYIQSNYINFGSGIVIPRTGIA
                     LHSRGNNFNLDPKHHNVVKPFKKPYHTIIPGFLGKEDKAIGPFGVMGAFMQPQGHIQV
                     LTNMIDFGLNPQEALDAPRWQWIKGKEIEVEPEMPKHIIDSLIEKGHEIKVIHDTVDM
                     GRGQIIFKTEQESYICGTESRCDGHIAVY"
     gene            complement(2840..4777)
                     /locus_tag="ACGI5H_003712"
     CDS             complement(2840..4777)
                     /locus_tag="ACGI5H_003712"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436722.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HFG9699386.1"
                     /translation="MTLFRIAMQNVKNSFFNYLMYFISIVFSVFVFFSFKSIEYNEAL
                     SSLGEKTRMSINTSSIVIVVFVFLFIYYSNSFFFNRRRREVGTYSLLGMRKNQIGKIF
                     LYETFLMGIVAILIGIFLGLLFSKLMTMMLVKLMNEMIVVNMNLSIKALVQTLAVFLI
                     IFIVIGIRNTIVIRNKRIIELFNKYPEKYKFKKFIKLKCVLGVLLIAISYLMSISYFI
                     AENIMLSVFILVTIIPGTFLFFSSTMYMIIDAVKKRKSFYYKGQNLIAFSELGFKLKS
                     NSSVLAVIAILIATSVTMLGFTISLYYDIDRNISENYKYSYTINLGNSYVNNEIDKLL
                     YKYKKDNKIIFDKTIELIDKDINIEMYYKNGNSYIEDRTSVDIIRESDFKKLRQYQNN
                     NYEELTSKESVYYVSDSYKKIFFKDFEVEKINLHIKDTNEYDINLFKVQKSILEPEIN
                     SQATFDLIVAKDDVFNQLKLHGNSRLIRLIDIKNEKKELDLTLKLKNIVSENMKFTYP
                     FNFTSSIESYNNLIKLSGLMLFIGIFLSVVFLLCTGSIILFKQLSNIYDDKERYIMLI
                     KLGANNKDIEKIISKQLKVIFLMPLVVGTVHNLFAMSIAQKFIPRSLLVPIIITLVIY
                     FIGYFIYYFLTLKYALNMIKE"
     gene            complement(4764..5531)
                     /locus_tag="ACGI5H_003713"
     CDS             complement(4764..5531)
                     /locus_tag="ACGI5H_003713"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420061.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HFG9699387.1"
                     /translation="MEEILSVENIKKEYGRKGSKHEALRGITFKVYKGEFVGIMGSSG
                     AGKSTLLNIISTIDLPSSGDIYINGKNTIKMKQNELADFRRDNLGFVFQDSNLLDTLT
                     IKENIMLPLSLKNERVSVIENRIKEISKELNIESILDKYPGEVSGGQKQRGAVCRAIA
                     TKPSLVLADEPTGALDSKSARDLLNCLLKLNKDSNKTILMVTHDAISASFCNRILFIK
                     DGIIFTEIVKGESNREFYNKIVNTVSLIGGVNKNDFI"
     gene            5819..6493
                     /locus_tag="ACGI5H_003714"
     CDS             5819..6493
                     /locus_tag="ACGI5H_003714"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429757.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator"
                     /protein_id="HFG9699388.1"
                     /translation="MFKIMVVEDDVSLKNIIAKCLTKWGHDVHQIENLENIIEEFKNY
                     NPELVLLDINLPFYDGFHWCNEIRKISKVPIIFISSRNSNMDVIMGVNLGADDYIQKP
                     FSVDVLVAKVNALLRRTYNFVDNNSNQIIHNGVTLDLSTATINYEDNTIELTKNEIKI
                     LHELMKYKGQIVSRNKLMKKLWDNDWFVDDNTLTVNVNRIRSKLNEIGLEDFIETKRG
                     LGYIIS"
     gene            6517..>7129
                     /locus_tag="ACGI5H_003715"
     CDS             6517..>7129
                     /locus_tag="ACGI5H_003715"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728538.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HFG9699389.1"
                     /translation="MSFKDFLKDKLGFLVYNFTFLIFTVSVIIFSPVDVFLTDTILYI
                     LVVNVVFLFLYLFISYIKKNKFLDKIKNDTFKINMNDIELARCKNEEKIYLNIIKNHQ
                     YQCNNIINNNIEKFEENKEILNMWVHDVKIPIAIIKLILEQNENLIDEKISDDIDSEI
                     FRIENSVEKILYLSRLEDFHKDFLIQEVNIEKIIRNIIKKYSKY"
BASE COUNT         2510 a         1041 c          846 g         2732 t
ORIGIN      
        1 cacaggaggt acattctttg aaaaacatta tttcagcaaa agaacttata tcaaaactag
       61 aaaaaaatga taatctagtt gtaatagatt gtagatttga tcttatcaat agaacttatg
      121 gtattgattc ttataaaaaa ggacacatca aaggcagttt tatcttagat atagacaagg
      181 atttatcatc tcctacaaaa gaacatggtg gtaaaaatcc tttacaagac cctttaatac
      241 taaaagaaaa attagaaaaa atgggtgttg ataatgacac tacgattgta acttatgatg
      301 atggagattt aaatggagct tgcagattat ttttccaatt aaaacatttg gggcttaaaa
      361 atgtctatgt actagatggg ggaataacat ctttcgtaaa ggaaggtgga gaattggaag
      421 agaaagtgaa tataccaagt tgtacaggta aggaaattag accaaatata aacaatgatt
      481 tagttgttcc aatggaatat gttaaatcta aattatacaa aaaagatact gtaataatag
      541 attgccgtgc taatgagaga taccagggtt tagttgaacc tgcttactca aaagctggtc
      601 atataccaag tgcaaaaaat tatttttgta aggatttaat aaaaagtgac tttgaaaatg
      661 gctcacttaa agatatagaa tttttaaaaa aattctttaa agatttaaat aattatgatg
      721 aagtaatttt atcttgtggt tcagggatat ctgcttgtgt taacagtctt gctcttagag
      781 aactggatat acctcacaag atttatattg gtagctttag tgactggatt agttatgatg
      841 acaatgaaat caaaactggt caagaataag gctcataatc tatataaaat cagcatatga
      901 tagcttaaat tttgtaaagg cgtcagtcat tgtagacttt cgcctttact tattatttca
      961 tatactcttt aaatttatta tatatatttt agttgataat attaataaac tgcaatatga
     1021 ccatcacatc ttgattccgt cccacaaata taactttcct gttctgtttt aaatattatt
     1081 tgacctcgtc ccatgtcgac agtatcatga attactttta tttcatgacc cttttcaatt
     1141 aatgaatcta ttatatgctt tggcatctct ggttcaactt ctatttcttt tccttttatc
     1201 cactgccatc ttggagcatc tagcgcctct tgtggattta atccaaaatc aatcatattt
     1261 gttaacactt gaatatgtcc ttgtggttgc ataaaagctc ccattacacc aaatggacct
     1321 attgctttat cttctttacc taaaaatcca ggtattatag tatgataagg ttttttaaat
     1381 ggttttacta cattgtggtg tttagggtct aaattaaaat tatttcctct actatgtaaa
     1441 gcaatcccag ttcttggtat cacaattcct gaaccaaaat ttatgtaatt gctctgtata
     1501 tatgaaacca tatttccatc cttatctgca gtacaaaggt atactgtacc accacaatat
     1561 ggctctcctg cagttggata caaagcctct ttattgtcaa tcaataaact tcttttttta
     1621 gcatactctt ggcttagtaa ttcctgaatc tttaccttca tatgctctat atcagttaca
     1681 tatgttttag aatctgcaaa agctaatttt aaactctcta taattttatg tatgtcttct
     1741 acattttcta tatttccttc taattccaat tcttttaata tgttaagtgc cattaaaact
     1801 gttattccat gaccatttgg tgggatttca aatattttat atcccttata ttctgtactt
     1861 ataggttcta cccatgttgg ataaaaacac tctaagtcac tctttcttat agccccatta
     1921 aattttttag aatattcatc tattttatca gcaagtcttc ctctataaaa gctttcagcc
     1981 tgagtatttg ctatctcttc taatgtactt gcctgttctt cacatataaa tatatctcca
     2041 gcctctggag ctttaccatc tttagaaaat gtatcaaacc atggtttgaa ctcttctcca
     2101 ataagttctt tttcatagag ttcatatgat tttttccata ccttagctac attaggagat
     2161 actacgtatc cctctcttgc atagtttatc gctggagata agcattccat taagctaagt
     2221 ttaccatatt ttttatttaa ttctgaccaa gctgctggta ttccaggtac agttactgct
     2281 ccaaacccat attttggcat ttctttcata ttattataat tttttaattc catattttct
     2341 ggagcaaagc cactagaatt taaaccatac aatcgttttt cttcctctat ccaaacaagg
     2401 gcatatgcgt ctcctccaat cccattgctt gtaggttcta ctactgctaa tgtggcggct
     2461 gttgcaactg ctgcatcaac agcatttcca ccctttttta gtatttcaag tccagcttga
     2521 gatgctaatg gtgttgatgt tgcaactgct ccatttttag catacacgac atttcttatt
     2581 gatgagtatt tatgttggta ggcattaaac ttcataaatt tcagctcctc gtcatttttt
     2641 atttgatatt ctgcttagat ttattatata acatcaagta atgtaactga tacaaaatga
     2701 tataaaatat agactttttc ctaactttaa ttttgtcttt aaataaatat cttaaactca
     2761 attctagtat tttctatctg cacttaaata agttatttta ttcaaaacat atatctaatt
     2821 cttttgactt aaaaataatt tattctttta tcatgtttag agcatatttt aaagttaaaa
     2881 aataatatat aaaatatcct ataaaataaa tgactagagt tatgataatt ggtacaagta
     2941 atgaccttgg tataaacttt tgtgctatag acatagcaaa taaattatga actgtaccta
     3001 caactaatgg cattaaaaat ataactttta actgttttga tattattttc tcaatatctt
     3061 tattatttgc tccaagtttt attaacataa tatatctttc cttatcatca tatatatttg
     3121 ataattgttt aaataagatt atactacctg tacataaaag aaatactaca gacaaaaata
     3181 tgcctataaa cagcattaga ccacttaatt ttatcaagtt attataactt tcaatacttg
     3241 atgtaaaatt aaaaggataa gtaaatttca tattttcact tactatattt tttaatttta
     3301 aagtcaaatc cagttctttt ttttcatttt ttatatcaat taatcttatt aatctagaat
     3361 ttccatgtaa ttttaactga ttaaatacgt catcttttgc tacaattaaa tcaaacgtag
     3421 cttgtgaatt tatttctggc tccaagatgc ttttttgtac tttaaacaga tttatatcat
     3481 actcatttgt atctttaata tgcaagttta ttttttcaac ctcaaagtct ttaaaaaata
     3541 tttttttgta tgaatcagaa acatagtaca cagattcctt tgaagttaat tcttcataat
     3601 tgttattctg atattgtctt aattttttaa aatcactttc tctaataata tctacagacg
     3661 ttctatcttc tatataacta tttccatttt tataatacat ttcaatattt atatctttgt
     3721 ctataagttc tattgtttta tcaaagatta tcttattatc ttttttatat ttatataata
     3781 atttgtcaat ttcgttattt acataagaat ttcctaaatt tatggtataa ctgtatttat
     3841 aattttcact tatgttccta tctatatcgt aataaagtga tatggtaaac cctagcatag
     3901 ttacacttgt agctattaat attgctatta cagccaatac actactattg ctctttaatt
     3961 taaatccaag ttcagaaaat gcaattaaat tctgtccctt ataataaaaa ctttttctct
     4021 tcttaacagc atcaataatc atatacatcg ttgatgaaaa aaataaaaaa gttccaggta
     4081 ttattgtaac taatataaaa actgaaagca taatattttc agcaataaaa taactaattg
     4141 acattaaata agaaatagct attaataaaa caccaagtac acattttaac tttataaatt
     4201 ttttaaactt atacttttct ggatatttat taaataactc tataattctc ttatttctga
     4261 taactatagt atttcttatt ccaataacta tgaatattat taaaaatacc gctagtgtct
     4321 gaactaaggc ctttatactt aagttcatat ttactactat catttcattc attaatttta
     4381 caagcatcat agtcataagc tttgaaaata acagtcctaa aaatatacct attagtattg
     4441 caactatacc catcaaaaaa gtttcatata aaaatatttt tcctatctga tttttcctca
     4501 ttccaagtaa actataagtt cctacttctc gcctacgtct attgaaaaaa aatgagtttg
     4561 aataatatat aaataaaaat acaaatacca ctattacaat tgaacttgta ttaatactca
     4621 tcctagtttt ctctccaagt gaactcaacg cttcattata ctctatagat ttaaaactaa
     4681 aaaatacaaa tacactaaat acaattgaaa taaagtacat taaataatta aaaaaactat
     4741 tctttacatt ttgcattgca attctaaata aagtcatttt tattaactcc tccaattaag
     4801 gaaactgtat ttactatttt attatagaac tctctgttac tttctccctt tacaatttct
     4861 gtgaatatta ttccatcctt tataaagagt attctattgc aaaaactcgc acttatagca
     4921 tcatgagtta ccatcaatat tgttttattg ctgtctttgt ttaattttaa tagacaattc
     4981 aacaaatccc tagcagattt agaatctaat gctcctgtag gctcatctgc aagtactaat
     5041 gatggttttg ttgctatagc tctacataca gctcctcttt gcttttgtcc accagaaact
     5101 tcgccagggt atttatctaa tatagattct atatttaatt cttttgaaat ctcttttatt
     5161 ctattttcta ttactgatac tctttcattt tttaaagaaa gaggcaacat tatattttct
     5221 tttattgtaa gtgtatccaa aagattagaa tcttgaaata caaagcctag attatcacgt
     5281 ctaaaatctg ccaattcatt ttgcttcatt ttaatagtat tctttccatt tatataaata
     5341 tctcctgatg aaggtaaatc tattgtagaa ataatattta aaagtgttga tttaccagca
     5401 ccggaagacc ccataatacc aacaaattct cctttataaa ccttgaaagt tattcctctt
     5461 agagcttcat gttttgaacc ttttcttcca tactcctttt ttatattttc aacagataat
     5521 atttcttcca tagttaataa tcacctttca tcacaattag ttatttatca attctcacaa
     5581 atatattata tatattaaaa tggcttttaa acatttaatt atattaattt aaggttacat
     5641 tttcgtaagt attaattata tttcttcaaa tttattgcaa ttatgtttaa aatataattt
     5701 atcaagtaaa atatagttat attaatataa ttattttagg taataaggta gaaatatttt
     5761 aatttatcaa gtagaatata gttatgttaa tataactatt ttgaattagg aggtaagaat
     5821 gtttaaaata atggtagttg aagatgacgt ctcattgaaa aatatcatag caaagtgtct
     5881 tactaaatgg ggacatgatg ttcatcaaat agaaaatctt gaaaatataa tagaagagtt
     5941 caaaaactat aacccagaat tagttttatt ggacataaac cttccatttt atgatggttt
     6001 tcattggtgt aatgaaataa gaaaaatttc aaaagttcct ataattttta tttcttcaag
     6061 aaattctaat atggatgtaa taatgggtgt aaatttaggt gcagatgatt atatacaaaa
     6121 acctttttct gtagatgtct tagtagctaa agttaatgcc cttttaagaa gaacttataa
     6181 ttttgttgat aataactcaa atcagattat tcacaatggt gttactttag atttatcaac
     6241 tgcaacaata aactatgaag ataatactat tgagctaaca aaaaatgaaa tcaaaattct
     6301 tcatgagctt atgaaatata aggggcagat agtaagtagg aataaactca tgaaaaaatt
     6361 atgggataat gattggtttg tagatgataa tacattaact gtcaatgtaa atagaatacg
     6421 ctcaaagtta aatgaaattg gtttagaaga ttttatagaa acaaaaagag gattgggtta
     6481 tataatcagt taaaacaatt ctaagtaggt gaatttatga gctttaaaga ttttctcaag
     6541 gataaactag gttttttagt atacaatttt actttcttaa tttttacagt atcagttatt
     6601 atattttctc ctgtagatgt ttttctgact gatactattt tatatatatt agttgtaaat
     6661 gttgtgtttt tatttttata tctatttatt agctacatca agaagaacaa atttttagat
     6721 aagataaaaa atgatacatt caaaattaat atgaatgata tagaattagc tagatgtaaa
     6781 aatgaagaaa aaatatactt gaacattatt aaaaatcatc aatatcaatg taataacata
     6841 ataaataata atatcgagaa atttgaagaa aacaaagaga ttttaaatat gtgggtacat
     6901 gatgtaaaga tacctatagc tataataaaa ctcattcttg aacaaaatga aaatttaatt
     6961 gatgaaaaaa tttcagatga catagatagt gaaatattta gaattgaaaa ctccgttgaa
     7021 aaaattttat atttatcaag actcgaagat tttcataagg attttttaat tcaagaggta
     7081 aatattgaaa aaatcattag aaatattata aaaaaatact caaaatatt
//
LOCUS       DAYAOO010000145         7119 bp    DNA     linear   BCT 12-OCT-2024
DEFINITION  TPA_asm: Clostridioides difficile isolate ST8-SSI-h139-18
            SAMN40601845-rid21577343.denovo.149, whole genome shotgun sequence.
ACCESSION   DAYAOO010000145 DAYAOO010000000
VERSION     DAYAOO010000145.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN40601845
            Sequence Read Archive: SRR28438827
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 7119)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7119)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-MAY-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-MAY-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002157583.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002157583.1
            Genome Coverage       :: 163x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/11/2024 16:19:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 4,038
            CDSs (total)                      :: 3,963
            Genes (coding)                    :: 3,930
            CDSs (with protein)               :: 3,930
            Genes (RNA)                       :: 75
            rRNAs                             :: 6, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 60
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 33
            CDSs (without protein)            :: 33
            Pseudo Genes (ambiguous residues) :: 0 of 33
            Pseudo Genes (frameshifted)       :: 7 of 33
            Pseudo Genes (incomplete)         :: 25 of 33
            Pseudo Genes (internal stop)      :: 11 of 33
            Pseudo Genes (multiple problems)  :: 8 of 33
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7119
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN40601845-rid21577343.denovo.149"
                     /isolate="ST8-SSI-h139-18"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Denmark"
                     /collection_date="2018"
                     /collected_by="Statens Serum Institute"
     gene            201..2246
                     /locus_tag="ACGI5H_003716"
     CDS             201..2246
                     /locus_tag="ACGI5H_003716"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893739.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0008134 - transcription factor binding
                     [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sigma 54-interacting transcriptional regulator"
                     /protein_id="HFG9699390.1"
                     /translation="MKKHNILFVSTDDKINIDISKQLENIFGEFCNIDNLVYVNRINI
                     ELSSYELVVCSDNDIKEYIHNNIDKNIPIVIVHRTINIENINQIISIENDSDVMVIDA
                     YKESADETAKIIRKLGLIHINLIPYYPGCDKSKCEIGIITGSRNSIPQNIKQIIDIGD
                     KVIDINTVIEIFTKLNISIDKLHIIKEKYNEDTVSGYRYYTTMNKTMKSFLEIIDEGI
                     ASVDKLGKFIYCNKVFSNLVGIDQNEIISNNFMDLFSDKVVKKIFFQEDEVNDEVVNL
                     NNKKLIINKVNVYENNERIKSIISIKNISAIQVLEDKIQNKLQSKGFVSKYTFESVVG
                     ESKIIKEKINIARKIATTDFSVLILGENGTGKEIFAQAIHNESLRKNKPFVAVNLSSL
                     SDTLIESELFGYDEGSFTGAIKGGKMGIFERAHTGTIFLDEIGDISLDVQQRLLRVLQ
                     EKEVMRMGGSKIIPIDVRIIAATNKDLKKKIKEGSFREDLYYRINVLHIEIPRLRERK
                     EDIPLISKYFLDEINSNKCFTEESMQALTLYEWPGNVRELKNLIYYIDTIVEEDRVDY
                     EHLPEQFRFEKNNTLVNENFDSIILDFKQSNFFEESICILTSIETWNNKNILLGRNKL
                     QEILKEKDIVLSVDQIRKRIDKLKSHGLLLSGVKKQGSFITDEGKNFISYVKIKGVI"
     gene            2507..3706
                     /locus_tag="ACGI5H_003717"
     CDS             2507..3706
                     /locus_tag="ACGI5H_003717"
                     /EC_number="3.4.13.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0070573 - metallodipeptidase activity
                     [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="membrane dipeptidase"
                     /protein_id="HFG9699391.1"
                     /translation="MKSAYKGYEAYSYLEKGKDISSIEMCKGDKRVKEYLIELDDIQE
                     AKVKSIVDEKIFISLHEHPVLFPEHLERDIFEYNREGKQRCAYEALSRGYYDAIFDNL
                     MDGVCTITSNSGWKWDDILIDLGMRLCDLAHQDFVIKCEKVEDIYRAKSEGKVALIPT
                     LEGAAPIENELDRIDILYGFGIRLMGITYSESNALGSGLKEEKDGGLTNFGKKAVERM
                     NKIGMAIDCSHVGVQTTLDVIEYSKDPIILSHVGARSLWNTKRLTPDEVLIACAKKGG
                     VIGVEAAPHTTITEKNKEHSIESFMEHFEYIKNLVGIDHVAFGPDTVYGDHVKLHSVL
                     AAKFDIKKITGTKEHPKVEYVKGLENPTETSKNIVRYLVKHGYSDEEIEKVLGGNILR
                     VLKQVWK"
     gene            3758..4453
                     /locus_tag="ACGI5H_003718"
     CDS             3758..4453
                     /locus_tag="ACGI5H_003718"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422731.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF5058 family protein"
                     /protein_id="HFG9699392.1"
                     /translation="MDYLKLANHPLLWIASTVAVSIVVVQSLIFAIKSCKVGKTMGIT
                     DKQIKSAVKSSAISAIGPSMTIFAGMVSLIVTMGGPIAWMRLSFIGSVIFESMSAGFG
                     TDALGITLGSPEMTKLAFTNAVWTMILGSLGWIIFTLLFGHKLDKITNVISSGKKSFI
                     PIISLGAMLGSFAYLNADRVLRFDNGTIACISGMAIMVILCMLEKKKNIKWLREWGLT
                     ISMFSGMIIASVI"
     gene            4466..5143
                     /locus_tag="ACGI5H_003719"
     CDS             4466..5143
                     /locus_tag="ACGI5H_003719"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426728.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9699393.1"
                     /translation="MSKVKSIYNEEYLPFMIRYGRLTLSLGIIAALVPGIILSFGFGI
                     MPPISALLASTMAIVSMSAPNYIIEPVSYSPILGIPGTYMSFLSGNISNMRLPCSIAA
                     QKAAEVESGTEEGSIISTIGIAVSILVNISILTIGVILGGSVLSKIPAEVVEKLNLIL
                     PALFGSVFGQVFLQDKKLGLVAIVISVLTIILSKQGIIPQSLVVLICVFGTILIARAM
                     YKDKLSD"
     gene            5254..6855
                     /locus_tag="ACGI5H_003720"
     CDS             5254..6855
                     /locus_tag="ACGI5H_003720"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439599.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidohydrolase family protein"
                     /protein_id="HFG9699394.1"
                     /translation="MIYDLILKNGFIIDGTGNPGFYGDIAIKDNLIAKIDSKINSNTN
                     KEIDCYGKIITPGFIDPHVHEEIVAILDGKFEKFLKQGVTTTINGNCGHSITPYSSEN
                     VYEYMYKNGLLLEEEKKYLIDKNKCWNNFTEYCDLISKSGISVNMGFLLGHGTIRWSV
                     MGGSKDRPPTEKEKNEITDIINDGMKSGAFGISTGLAYIPSKYADIDELVDIARQIKE
                     HDGIYTSHIRDYIGRYNAVKEAIEVGQKSGARVQVSHLSPVEIEAFDEILKARYNGVE
                     IMVDTVPRSSGHCMKKKRVIQFIMAISSSLFELGIDGVMDALRNEEGRTLILKEAFIL
                     GDRGSIILLNTKDINMEKKSIREIATQKGIDEDKLLLDLLLDGDEELIFCLGGMYRAD
                     FPDKLHDDKIIDNPFVMVGSDCLFSVGGDMSWFELQRRGAFPIFFNMYRKSGVRLEEI
                     VRRVTSLPARQFKIKNRGILKEGLIADIAVIDMDNYSYPRSEDIDFSKPQLLANGVEY
                     VIVNGKIALENGEITENKCGEVLKR"
BASE COUNT         2862 a          703 c         1321 g         2233 t
ORIGIN      
        1 tttatttata ttccaataat gtcaaactaa ccgttttaga aattaaatta tatgtgaaaa
       61 aagatagctt acattatttt attatggaaa ataatagtaa atggtacaaa atttgatttt
      121 taagatttaa aactttttta aaaagtgcta caatagacca aattattact ttctatactc
      181 gttaaacagg aggtgggact atgaaaaaac ataatatttt atttgtatca actgatgaca
      241 aaataaatat agatatatca aaacaattgg aaaatatatt tggagaattt tgtaatatag
      301 ataacttggt atatgtaaat aggataaata ttgaactgtc aagctatgag cttgtagtat
      361 gttcagacaa tgatataaag gaatatatac ataataatat tgataaaaat atacctattg
      421 taatagtaca tcgtactata aatattgaaa atataaatca gataataagt atagaaaatg
      481 attctgatgt tatggttata gatgcttata aagagtcagc agatgaaact gccaagataa
      541 ttagaaaact aggattaatt catattaatc taataccata ttatccaggt tgtgataagt
      601 ctaaatgtga gattggaatt attacgggaa gcagaaacag cataccacaa aacataaagc
      661 aaataattga cataggtgat aaggtaattg atataaatac agttatagaa atctttacaa
      721 aactaaatat atctatagat aaactacata ttattaagga aaaatacaat gaagatacag
      781 taagtggata taggtattat acaactatga ataaaaccat gaagagtttt ttggagatta
      841 tagatgaagg tattgcttct gttgataaat taggaaaatt tatatattgc aacaaagtat
      901 tttctaatct agttggaata gaccaaaatg aaattatatc taataacttt atggacttat
      961 ttagtgataa ggttgtcaaa aaaatatttt ttcaagaaga tgaagttaat gatgaagtag
     1021 taaatttaaa taacaaaaaa ctgataatta ataaagtaaa tgtttatgaa aataatgaac
     1081 gaataaagag tattataagc attaaaaata taagtgcaat tcaagtgctt gaggacaaga
     1141 ttcaaaataa acttcagtca aaaggttttg tatcaaagta tacatttgag agtgttgtag
     1201 gtgagagtaa aataataaaa gaaaaaatta atattgcaag aaaaatagca actacagact
     1261 tttctgtgtt gatacttgga gaaaatggaa caggaaaaga aatatttgcc caggcaatac
     1321 ataatgaatc tctaagaaaa aacaagccat ttgttgcagt taatctatct tctttgtcag
     1381 atacacttat tgaaagtgaa ctttttggct atgatgaagg aagttttaca ggagcaataa
     1441 aaggtggaaa aatgggtata tttgaaagag cacatacagg aacaattttt ttagatgaga
     1501 taggtgatat atctttagat gtacagcaga gattgctaag agtattacag gaaaaagaag
     1561 ttatgagaat gggcggaagt aaaattatac caatagatgt tagaattata gctgcaacaa
     1621 ataaagattt aaagaaaaaa attaaagaag gttcttttag agaagatttg tattatagga
     1681 ttaatgtatt acatatagag atacctagac ttagagaacg taaggaagat atacctctta
     1741 taagtaagta ttttttagat gaaataaata gcaacaaatg ttttacagag gaatcaatgc
     1801 aagctttaac attgtatgaa tggccaggaa atgtaagaga gcttaaaaat ttaatttatt
     1861 atattgatac tatagttgag gaagatagag tagattacga gcatttgcca gaacaattta
     1921 gatttgaaaa aaacaatact ttagttaatg aaaatttcga ttcaattatc ttagatttca
     1981 aacaatctaa tttctttgag gaaagtatat gtatattgac cagtatagaa acttggaata
     2041 ataaaaatat attattagga agaaataaac tgcaagagat tttaaaagaa aaagatatag
     2101 ttttaagtgt agaccaaatt agaaaaagaa tagataagtt aaagagccat ggtttacttt
     2161 tatctggagt aaaaaaacaa ggtagtttta taactgatga aggaaagaac tttatatcat
     2221 atgtaaaaat taagggagtg atatagggga ctaaaaaggc aaaacaccct aaaaaaatcc
     2281 ctataatgga tagaaataaa taaaattatc tttaagatta agataattca aaaatattga
     2341 ataaataatc taagaagatt atttttaata aaacagtagt aaatatcaac cttactactg
     2401 tttttatttt ttgcaagatt tattatacaa ttaaaattta tattttggca catcaattgc
     2461 tacataggaa aaatataaaa aattgtagaa cttggaggat gttgttatga agtcagctta
     2521 caaaggatat gaagcctata gttatttaga aaaaggaaaa gatatttcat ctattgagat
     2581 gtgtaaagga gataaaagag ttaaagaata ccttattgaa ttagatgata ttcaagaagc
     2641 taaggttaaa agtatagtgg atgaaaaaat atttatatca ttacatgaac atccagtatt
     2701 atttccagaa cacctagaaa gagatatatt tgaatataat agggaaggta aacaaagatg
     2761 tgcttatgaa gcattatcaa gaggatatta tgatgctata tttgataatt taatggatgg
     2821 tgtatgtacg ataacatcaa attcagggtg gaaatgggat gatatattaa tagatttagg
     2881 catgagacta tgtgatttag ctcatcaaga ttttgttata aagtgtgaaa aagtagaaga
     2941 tatatacaga gctaaaagtg aaggtaaagt agcattgata ccaacattag aaggtgcagc
     3001 accaatagaa aatgaacttg atagaataga tatactgtat ggatttggta taaggttaat
     3061 gggtataaca tacagcgaat ccaatgcatt aggttcagga ctaaaagaag agaaagatgg
     3121 aggtcttaca aatttcggaa aaaaagctgt tgaaagaatg aataaaattg gaatggcaat
     3181 agattgctct cacgttggag ttcaaactac acttgatgta atagaatata gcaaggaccc
     3241 aataatatta agccatgttg gggcaagaag tttatggaac acaaagagac taactccaga
     3301 tgaagtatta atagcatgtg ctaaaaaagg aggggttata ggtgtagaag cagcacctca
     3361 tactacaata acagagaaga ataaagaaca ttcaatagag tcatttatgg aacattttga
     3421 gtatattaaa aatttagtag gaatagacca tgtagctttt ggaccagata cagtatatgg
     3481 cgaccatgta aaattacact cagtactagc tgctaaattt gatataaaaa aaataacagg
     3541 aacaaaagaa catcccaaag tagaatatgt aaaaggtctt gagaacccaa cagaaacttc
     3601 aaaaaacatt gttagatatt tagtaaagca tggatatagt gatgaggaaa tagagaaggt
     3661 actaggtgga aatatactta gagtactaaa acaggtttgg aaatagatat attagaaata
     3721 ttaataaaat ttgaggattt atagggaggt tttataaatg gattatttaa aattagctaa
     3781 tcatccactt ttgtggatag cgagtacagt agcagtatca atagtagtgg tacaatccct
     3841 tatatttgct ataaaatctt gcaaagttgg taaaacaatg ggaataacag ataaacaaat
     3901 aaagtcagct gttaagagta gtgctatttc agctattggg ccttcaatga ctatatttgc
     3961 tggaatggta tcgcttatag taactatggg tgggcctata gcatggatga gattatcatt
     4021 tataggttct gtaatttttg aatcaatgtc agccggattt ggaacagatg cattaggtat
     4081 aactttaggt tctcctgaaa tgacaaaact tgcatttaca aatgcagttt ggactatgat
     4141 attaggttct ttaggatgga taatattcac attactattt ggacataaac tagataagat
     4201 aaccaatgtt atatctagtg gcaagaaatc atttatacca ataatatctc taggagcaat
     4261 gttgggttca tttgcatatc taaatgctga tagggtgttg cgttttgata atggaacaat
     4321 tgcatgtata agtggaatgg ctataatggt aatattgtgt atgcttgaaa agaagaaaaa
     4381 tataaaatgg ttaagagagt gggggcttac aatatcaatg tttagcggaa tgataatagc
     4441 ttcagtaata taagggggga gttttatgag taaagtaaaa tctatataca atgaagaata
     4501 tttacctttt atgataaggt atggaagact aacactatct ttgggtatta tagcagcatt
     4561 agttcctgga ataattttga gctttggatt tggtattatg cctccaatat cagcattatt
     4621 agcaagtaca atggcaattg tcagtatgag tgctccaaat tacataatag aaccagtttc
     4681 ttattcacca atcttaggta tcccaggaac ttatatgagt tttctttctg gtaatatatc
     4741 taatatgagg ctaccatgtt caatagcagc tcaaaaggca gcagaagttg aatcaggtac
     4801 agaagaaggc tcgataatat ctacaatagg aatagctgta tctattttag tgaatataag
     4861 tatactaact ataggggtaa ttttaggagg aagcgtacta tctaaaattc cagctgaagt
     4921 agtagaaaaa ttaaacttaa ttttaccagc tctatttggg tcagtttttg gacaagtatt
     4981 tttacaagat aaaaaattag gtctagtagc aattgtaata tctgtattga ctattatatt
     5041 atcaaagcaa ggtataatac cacagtctct agtagttctt atatgtgtat ttggtactat
     5101 attaattgca agagctatgt ataaagataa gcttagtgac taattacaat gaaataatag
     5161 tgaattttca aatatgaaat ttaataattt gattttcaaa tataaaaatt acattaagat
     5221 tatttaaaaa ttggttttta aggagggaat attttgatat atgatttaat cttaaaaaat
     5281 ggatttataa tagatggtac aggtaatcct ggtttttatg gagatatagc aattaaagac
     5341 aacttaatag caaaaataga ttctaagata aatagcaata caaataaaga gattgattgt
     5401 tatggaaaaa ttataacacc tggatttatt gaccctcatg ttcatgaaga aatagtagca
     5461 atactagatg gtaaatttga aaagtttcta aaacaaggag ttacaacaac tataaatggt
     5521 aattgtggac attctataac accatattct tctgaaaatg tatatgaata tatgtataaa
     5581 aatggtctat tacttgaaga agaaaaaaag tatcttatag ataaaaataa atgttggaat
     5641 aattttacag aatattgtga ccttatatct aaaagtggta tttctgtcaa tatgggattc
     5701 ttgttggggc atgggactat aagatggagt gttatgggag gttctaagga tagacctcct
     5761 acagaaaagg aaaaaaatga aattacagat ataataaatg atggaatgaa aagtggtgct
     5821 tttggaatat ctactggatt ggcatatata ccaagtaagt atgctgatat tgatgaactt
     5881 gttgatattg caaggcagat taaagagcat gatggtatat atacatctca tattagagat
     5941 tacataggaa gatataatgc agtaaaagaa gccatagagg ttgggcagaa aagtggtgct
     6001 agggttcaag tatctcactt aagtccagtt gaaatagaag catttgatga gatattaaag
     6061 gctaggtata atggtgttga aataatggtt gacacagtac caagaagttc tgggcattgt
     6121 atgaagaaaa aaagagtaat tcaatttatt atggcaatat catctagtct atttgaatta
     6181 ggtatagatg gggtaatgga tgctcttaga aatgaagagg gaagaacact tatattaaaa
     6241 gaagcattta tacttggaga tagggggagt ataatacttc taaacactaa agatattaat
     6301 atggaaaaga aatcaatacg tgaaatagct acacaaaaag gaatagatga ggacaagtta
     6361 ttactcgatt tacttttaga tggagacgaa gaacttatct tttgtttagg aggaatgtat
     6421 agagctgatt tcccagataa actacatgat gataaaataa ttgataatcc atttgttatg
     6481 gttggttcag attgtttgtt tagtgtgggt ggggatatgt catggtttga actacaaaga
     6541 agaggagctt ttccaatttt cttcaatatg tacagaaagt ctggtgttag attggaagag
     6601 attgtaagaa gagttacttc attaccagct aggcaattta aaataaaaaa tagaggtatt
     6661 cttaaagaag ggttgatagc tgatatagca gttattgaca tggataacta tagttatcct
     6721 aggtcagaag atattgattt ttcaaagcca caattactag ccaatggtgt tgaatatgta
     6781 attgtaaatg gaaaaattgc gctagaaaat ggagagatta ctgagaataa atgtggtgaa
     6841 gtattaaaaa gataaggttt taaaaataat aggatttaga aagtaaataa atatctaagt
     6901 aagtaaagac gaagtttgag atttatttaa ataaaaatca tgcttcgttt ttatttatag
     6961 tattaatatt tattttaata atcagataat atttatactt tatagtgaaa aaattaatat
     7021 ttttaatcat taaattatgt aaaaaattgg ataaatagat aactaaatca tttgagaaaa
     7081 gatttttaga aataaaaaat gataactaaa taacccctt
//
LOCUS       DAYAOO010000146         6841 bp    DNA     linear   BCT 12-OCT-2024
DEFINITION  TPA_asm: Clostridioides difficile isolate ST8-SSI-h139-18
            SAMN40601845-rid21577343.denovo.150, whole genome shotgun sequence.
ACCESSION   DAYAOO010000146 DAYAOO010000000
VERSION     DAYAOO010000146.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN40601845
            Sequence Read Archive: SRR28438827
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 6841)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6841)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-MAY-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-MAY-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002157583.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002157583.1
            Genome Coverage       :: 163x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/11/2024 16:19:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 4,038
            CDSs (total)                      :: 3,963
            Genes (coding)                    :: 3,930
            CDSs (with protein)               :: 3,930
            Genes (RNA)                       :: 75
            rRNAs                             :: 6, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 60
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 33
            CDSs (without protein)            :: 33
            Pseudo Genes (ambiguous residues) :: 0 of 33
            Pseudo Genes (frameshifted)       :: 7 of 33
            Pseudo Genes (incomplete)         :: 25 of 33
            Pseudo Genes (internal stop)      :: 11 of 33
            Pseudo Genes (multiple problems)  :: 8 of 33
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6841
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN40601845-rid21577343.denovo.150"
                     /isolate="ST8-SSI-h139-18"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Denmark"
                     /collection_date="2018"
                     /collected_by="Statens Serum Institute"
     gene            complement(451..1770)
                     /locus_tag="ACGI5H_003721"
     CDS             complement(451..1770)
                     /locus_tag="ACGI5H_003721"
                     /EC_number="2.7.13.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439056.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000155 - phosphorelay sensor kinase
                     activity [Evidence IEA];
                     GO_function: GO:0004673 - protein histidine kinase
                     activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0007165 - signal transduction [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HFG9699395.1"
                     /translation="MLNINVFWIFLPIFSTAIEWIVLKFLLNEFSELRKNRLTLNSSI
                     VIAIMIITMLNTIEFNINIKLFICIFITYVLYKINYVVDKWKSVFISLLYWMLLIGFD
                     SIGLSIVMTLNSIKNMNDLLEDNLLKLELIMISKSLLIVLIPLLKFIRLKTKINKRDC
                     IYLSIPLIANIIGVIVIFEFIFKDKIIDSKESLIILTISTVFLLSNLSLVSIIGRIIK
                     DNSLKIEYEITKKRMNMQYKYYLNLQEYQLKIRKLYHDMNNHIICIQNVYGKNEFADK
                     YIKDINKQIKECNTIFNTQNMILDVILSDKKSICDMNNIYFLVDINFLECNFIEMPDI
                     CSIFSNIIDNAIEACIKIKDTSIQKKIKLRGTVINRLFVIKCENTKINEVVLKNNKVI
                     TSKKDSFLHGIGISSVKSSVEKYNGNVEIYSDKNKFTITIYIPLTRN"
     gene            complement(1764..1907)
                     /locus_tag="ACGI5H_003722"
                     /pseudo
     CDS             complement(1764..1907)
                     /locus_tag="ACGI5H_003722"
                     /inference="COORDINATES: protein motif:HMM:NF016296.4"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="LytTR family transcriptional regulator
                     DNA-binding domain-containing protein"
     gene            complement(2031..2741)
                     /locus_tag="ACGI5H_003723"
     CDS             complement(2031..2741)
                     /locus_tag="ACGI5H_003723"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439052.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LytR/AlgR family response regulator
                     transcription factor"
                     /protein_id="HFG9699396.1"
                     /translation="MYRIVICEDDITQIAFLRECILKSLEGISSQIELFEFNSGEELL
                     ETNLEGIDIFFLDIKMLQLTGMDVAKIIRETNDTSEIIFITSIVDYIQEGYKVRAYRY
                     LLKPIDFGDLNESILSCISDIIKKRENFMLIENKGIINKILINSIMYIEVRKKVLTIH
                     TKNDTYYTKNSMDKIELELEKYNFFRCHKSYLINLEYIQFICKKTVVINDEDVPVSKY
                     RMADLKKKLTYVLGDVLC"
     gene            complement(3832..6573)
                     /locus_tag="ACGI5H_003724"
     CDS             complement(3832..6573)
                     /locus_tag="ACGI5H_003724"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014466356.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall-binding repeat-containing protein"
                     /protein_id="HFG9699397.1"
                     /translation="MKIPKKIAAMLTVTMIAGSSTAGIASAQTVATNLTGQERYETAV
                     KISQDGWKNADEVVIVNDSSIADALSATPFAKAKNAPILLTSKDKLNDKTKAEIQRLK
                     AKKVYLIGGTSVLSTNIEKEIKDLKISFERISGAERYQTSLELAKKLDAISDVKKIAV
                     VNGEKGLADAVSVGAPAAQNNMPVILADSKNGTAVADKFIKDAGITQSYVVGGESSIS
                     EAVKNKLPNSTRLGGTDRNDTNAKVIKEFYKKTDLKNAYVTKDGMNKQDQLIDALAVG
                     VLGAKNQSPVVLVGKNLSASQKSLVNSKSFDKITKVGGNGNETAFNEMKSLQEVKTVE
                     AKTISELKSAIDKATANDVINFKPTSEVKEAFTIQTDKAVTVNLNGTYTKTVTINMPN
                     GDVNNYAKVDDVVIDDVKDGTFVNYGKITNLKVNDKNGAKIENNSKGEIGSLTVASGA
                     SQVKVTNGGKITTVTNNSKGTTIDNKGTISSVKGDNSPTISGNSPSSNSSGGSSSSGG
                     SSHGGGSSSGGSSSNQTSVNNEAAKITSVPTPAKDATRLTMPSVSSGYTIAIKTSSNE
                     SVIKKDGTIIPPNTATTVKLVFTVTHTSSGKTADTKELSVTVPAKSTDEELQAALDNE
                     VAKITSVPAPAKDATKLTMPSVSSGYTIAIKTSSNKSVIKEDGTIIPPNTEETVTLVF
                     TVTQESSGKTADTGEIDVVVPAKSTDGEIQAEVQAEADKITSVTQPTQDATTLTMPTV
                     ASGYTIKIKSSTNESVIAKDGTIVPPDTETKVTLVFTVTHTSSGKTADTGEIEVTVPA
                     RTAIDTEQLAVQAEADKITSVTQPTQDATTLTMPTVASGYTIKIKSSTNESVIAKDGT
                     IVPPDTETKVTLVFTVTHTSSGKTADTGEIEVTVPARTTTVSSLLGRIAVNIFNFNK"
BASE COUNT         2175 a         1071 c          704 g         2891 t
ORIGIN      
        1 aaattagtaa aatatttttc tttaatattt attactaata tcaactttac tatctaatta
       61 gttatttaat tgttgttttt atgttcctag ttataaagtt tatcaaattt acattttatt
      121 tttttatact atatagaact tttggtcaat aatgttacca tactaaggtc gcatttgcag
      181 ataaaaataa ctctattttt ctaaatttat ttaagatata tcatgcaaat aatataacta
      241 taaaacctat caacatttta aattcaaaca aatataaatc acattttttg ttctattatt
      301 ttattgagta ctaaaaagga tgttatctta ttagcatagc attcaaccat ttttatcacc
      361 tccaaatatc ctatgcctta aagatagcat cttctatttt atctttcaat actactgctc
      421 caactgggca atttagagcc ccaactagaa ttagttccta gttaatggta tataaatagt
      481 aattgtaaac ttgtttttat ctgagtatat ttccacattt ccattatatt tttctactga
      541 actttttaca ctacttattc ctattccatg taaaaaggaa tctttcttac ttgtaataac
      601 cttattattt tttaatacaa cttcatttat ctttgtattt tcacatttta ttacaaataa
      661 cctatttata acagttcctc ttaatttaat ctttttttgt atacttgtgt ccttaatctt
      721 aatacaagct tctattgcat tatctattat atttgaaaat atactacata tatctggcat
      781 ctctataaaa ttacattcta aaaaattaat atctactaga aaatatatat tattcatatc
      841 acaaatagat tttttatcac ttaaaataac atctagaatc atattctgag tattaaatat
      901 agtattacat tcttttattt gcttatttat atctttaata tacttatctg caaactcatt
      961 tttcccataa acattctgaa tacaaatgat atgattattc atatcatgat atagttttct
     1021 tattttcaac tgatattcct gtaaatttaa ataatattta tattgcatat tcattctttt
     1081 ttttgtaatt tcatattcta tctttaaact attatctttt attattcttc ctattatgct
     1141 tactaatgaa agatttgata gtaaaaatac agttgatatt gtaagtatta ttaaactctc
     1201 tttagaatcg ataatcttat ctttaaaaat aaattcaaat attactatta caccaataat
     1261 gtttgctatt aatggaatag ataaatatat acaatccctc ttgtttattt ttgtttttaa
     1321 tctgataaac ttaagcaatg gtattaatac tattagtaat gatttagata tcattattaa
     1381 ctctaacttc aacaaattat cctctaataa atcattcata ttttttatag aattaagtgt
     1441 cattactata cttaatccaa tactatcaaa tccaattaat aacatccaat atagcaaact
     1501 tataaataca cttttccatt tatccactac ataatttatt ttatacaata catatgtaat
     1561 aaatatacat ataaataatt taatatttat attaaactca attgtattca acatagtaat
     1621 tatcataata gcaattacta tgctactatt tagggttaat ctattctttc ttaactcact
     1681 aaattcattt aataaaaatt ttaatacaat ccattctatc gccgtagaaa atataggtaa
     1741 aaaaatccaa aatacattta tatttaacat aatacatctc ccaatacata tgttaatttt
     1801 ttctttaaat tagccattct atatttacta actggtatat ctttaccatt aataactaca
     1861 gtatttttac atataaattg aatatactcc aaattaatta aatagctctt gtaacatttt
     1921 taaaaattta ttctttctta aatcactgaa ttcatttgat aaaaatttta atacaattca
     1981 ttctatcgcc gtagaaaata taggtaaaaa aatccaaaat acatttatat ctaacataat
     2041 acatctccca atacatatgt taattttttc tttaaatcag ccattctata tttactaact
     2101 ggtacatctt catcattaat aaccacagtc tttttacata taaattgaat atactccaaa
     2161 ttaattaaat agctcttatg acatctaaaa aaattatatt tttctagctc taattctatt
     2221 ttatccatac tatttttagt ataataagta tcatttttag tatgtatagt caaaaccttt
     2281 ttcctaacct ctatatacat aatactatta attaaaattt tattgattat acctttattt
     2341 tctatcagca taaaattttc tctttttttt ataatatccg atatacaact caaaatactt
     2401 tcatttaaat ctccaaaatc tataggcttt aataaatatc tataagccct taccttatag
     2461 ccttcctgta tgtaatcaac tattgaagtt ataaatatta tttcagaagt atcattagtt
     2521 tctctaatta ttttagccac atccatgcct gttagttgaa gcattttaat atctaaaaaa
     2581 aatatatcaa taccttctaa atttgtttcc aataattctt ctcctgaatt aaactcaaat
     2641 agttcaattt gactagaaat accctctaag gactttaata tacactctct taaaaaagct
     2701 atttgtgtaa tatcatcctc acagataact attctataca taaacacccc tccttagaca
     2761 ttagatctga aaacaaataa aatatcaatt tataaataat tatttagtta tacaactaac
     2821 atggtcatca aatactatta ttcacttaaa aaatcacccc ctatttttag tatgttaaca
     2881 acaaaataag aagatatctt agatttttaa aaacaattaa tacttaatgt agttttgtat
     2941 actatttata ggtaattttt tatatcattt taaacattaa aattattgat gtttaagaac
     3001 tattatattg atagtaatat ataattaatg atatcaaaaa tttttaatta gacttctctc
     3061 ttattcaaga tttttctata taaaatctaa gaataaatag aaaactaaca tctaaccttt
     3121 tattttttat tttcgatcta tttacttgaa ttttaacata aatctatctt ttagtatata
     3181 ttaatcatgc tgaatttgtg atgacatgta tacaaaatat cgtttagtat tttctaataa
     3241 aaaatattac tgaaattaaa aatctacaat agcatttaac aagtaaaaac atgtttacac
     3301 aaatatataa tttaaggtct ttaaaataga gtatgtatta ttctaaaaat tagttatagt
     3361 tatcacataa aaatagaaaa gaattttcaa aagatttaaa gaacatatat acttcaattg
     3421 cagaagatgt aatgttaagt gaactagcat tcttcgagga aaaatagact caaaaaatta
     3481 gaaaatagaa tcaggtttta gatgatttaa gtatttattt tcaaaaaaga aatttgattc
     3541 taagttaata aagaaatatt taaaaaaatc aaaaaatttt cttaaataag taataggttt
     3601 tgtaaaaatg gaaaaatatc aaaataagac tatgattttt aaaactatag ccttatcaat
     3661 aaatttttat ttaaagaaca cacataaata tttttaaacc taatttatgt gaagttttat
     3721 gtatttttta tataagtagt attctaatct tactcatcta atataccaaa aagactgtaa
     3781 gtaagttcac ttttatgcaa acttacccac aatctctttt acacattaat tctatttatt
     3841 aaaattaaaa atatttactg ctattctacc caataaagat gatactgttg ttgttctggc
     3901 tggtactgtt acttctattt ctcctgtatc tgctgtttta ccacttgatg tgtgtgtcac
     3961 tgtaaatact aatgttactt ttgtttctgt atctggtggc actattgttc catctttcgc
     4021 tataacactt tcatttgttg atgattttat ctttattgtg tatccacttg ctactgttgg
     4081 catagttagt gttgttgcat cttgtgttgg ctgagttaca cttgttattt tatctgcctc
     4141 agcttgtact gccaattgtt ctgtatctat agctgttctg gctggtactg ttacttctat
     4201 ttctcctgta tctgctgttt taccacttga tgtgtgtgtc actgtaaata ctaatgttac
     4261 ttttgtttct gtatctggtg gcactattgt tccatctttt gctataacac tttcatttgt
     4321 tgatgatttt atctttattg tgtatccact tgctactgtt ggcatagtta gtgttgttgc
     4381 atcttgtgtt ggctgagtta cacttgttat tttatccgcc tcagcttgta cttctgcttg
     4441 tatttcccca tctgttgatt tggctggtac tactacatct atttctcctg tatctgctgt
     4501 tttaccactt gattcttgtg ttactgtaaa taccaatgtt actgtttcct ctgtatttgg
     4561 aggtattatt gttccatctt cctttataac actcttattg cttgatgttt ttattgctat
     4621 agtatatcca cttgatactg atggcatagt taatttagtt gcatcttttg ctggtgcagg
     4681 aacgcttgtt atttttgcca cttcattgtc taatgctgct tgtaattctt catctgttga
     4741 tttagctggt actgttacag ataattcttt tgtatctgct gttttaccac ttgatgtatg
     4801 tgttaccgta aatactaatt ttactgttgt tgctgtattt ggaggtatta ttgttccatc
     4861 tttttttata acactctcat tacttgatgt ttttattgct atagtatatc cacttgatac
     4921 tgatggcata gttaatctag ttgcatcttt tgctggtgta ggcacgcttg ttatttttgc
     4981 tgcttcatta tttactgatg tttgattaga agaacttcct cctgaagatg agcctcctcc
     5041 atgtgaagaa cctccacttg atgaacttcc tcctgaagag ttagaacttg gactatttcc
     5101 acttattgtt ggagaattat ctcccttaac actacttatt gtacctttat tatctatagt
     5161 agtcccttta gaattatttg taactgtagt tatcttacca ccattagtca cttttacttg
     5221 acttgctcca gatgctactg ttaaactacc aatctcacct ttagaattat tttctatctt
     5281 ggctccattt ttatcattaa cctttaagtt agttattttt ccataattaa caaaagttcc
     5341 atcttttaca tcatctataa ctacatcatc cacttttgca tagttattta catcaccatt
     5401 aggcatgttg atagtcacag tctttgtata tgtaccattt aagtttactg ttactgcttt
     5461 atcagtttgt attgtaaatg cttctttaac ctcactagtt ggcttaaagt ttataacatc
     5521 attagcagta gctttatcta tagctgattt taattcagaa attgttttag cttcaactgt
     5581 ttttacttct tgtaatgact tcatttcatt aaatgctgtc tcattaccat tcccaccaac
     5641 tttagttatc ttatcaaaac tcttagagtt aactagagat ttttgtgaag ctgataagtt
     5701 ctttccaact aaaactactg gtgattgatt tttagcacct aatacaccta ctgctagtgc
     5761 atctataagt tggtcttgtt tattcatacc atctttagtt acataagcat tttttaaatc
     5821 tgtcttttta taaaattctt ttattacttt tgcatttgta tcatttctat ctgttccacc
     5881 tagtcttgta ctatttggta gtttattttt aacagcttca gaaattgaac tctctccacc
     5941 tactacataa gattgagtta ttccagcatc ctttataaat ttgtctgcaa ctgctgttcc
     6001 atttttagaa tcagcaagta ttactggcat attgttttgt gcagctggtg ctcctacact
     6061 tacagcatct gcaagtcctt tttcaccatt aactacagct attttcttaa catcacttat
     6121 agcatctaat ttctttgcta attctaagga tgtttgatat ctctcagctc cagagattct
     6181 ctcaaaagat atttttaaat cttttatttc tttttctata tttgtactta atacagaagt
     6241 tccacctatt aagtatactt ttttagcttt taatctttgt atttctgctt tcgtcttatc
     6301 atttaattta tctttacttg ttaaaagtat tggagcattt tttgcttttg caaatggtgt
     6361 tgcagataga gcatctgcta tagatgagtc gtttacgatt actacctcat cagcattttt
     6421 ccatccatct tgacttattt taacagcagt ttcatatctt tcttgccctg ttaaatttgt
     6481 tgccacagtt tgtgcactag ctatgcctgc tgttgaactt ccagctatca ttgtaactgt
     6541 aagcattgca gcaatcttct ttggtatttt cattttattt tcttccccct tgtccatttg
     6601 atattactta attttttaac tttgttcccg ttctaattct aaaggatact taatatctaa
     6661 ttttaaagag gtttctaact ataatgattt cataattaat ttgtaattat tttgttacat
     6721 tgcagtcatt atgtaaggaa taaagaaatt ttcttattga ttgaaaaatt tgtaaattta
     6781 tattttaagg taagtttgat ttttatgtta atgaattgtt ataaaaaata gggttttgta
     6841 t
//
LOCUS       DAYAOO010000147         6793 bp    DNA     linear   BCT 12-OCT-2024
DEFINITION  TPA_asm: Clostridioides difficile isolate ST8-SSI-h139-18
            SAMN40601845-rid21577343.denovo.151, whole genome shotgun sequence.
ACCESSION   DAYAOO010000147 DAYAOO010000000
VERSION     DAYAOO010000147.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN40601845
            Sequence Read Archive: SRR28438827
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 6793)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6793)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-MAY-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-MAY-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002157583.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002157583.1
            Genome Coverage       :: 163x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/11/2024 16:19:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 4,038
            CDSs (total)                      :: 3,963
            Genes (coding)                    :: 3,930
            CDSs (with protein)               :: 3,930
            Genes (RNA)                       :: 75
            rRNAs                             :: 6, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 60
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 33
            CDSs (without protein)            :: 33
            Pseudo Genes (ambiguous residues) :: 0 of 33
            Pseudo Genes (frameshifted)       :: 7 of 33
            Pseudo Genes (incomplete)         :: 25 of 33
            Pseudo Genes (internal stop)      :: 11 of 33
            Pseudo Genes (multiple problems)  :: 8 of 33
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6793
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN40601845-rid21577343.denovo.151"
                     /isolate="ST8-SSI-h139-18"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Denmark"
                     /collection_date="2018"
                     /collected_by="Statens Serum Institute"
     gene            complement(651..1058)
                     /locus_tag="ACGI5H_003725"
     CDS             complement(651..1058)
                     /locus_tag="ACGI5H_003725"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipid II flippase MurJ"
                     /protein_id="HFG9699398.1"
                     /translation="MSKVAKATFYLMIVTIISKILGMGRELVLSSIYGTGLYTESYLT
                     AMNIPNIIFAAIGTAIVTTFIPMYQDISSKQGEKQALKFLNNVLNIIVGICIVVAILG
                     VIFSKQLVSIFAIGFEGERFLLTVKFTKILIKK"
     gene            complement(1532..2416)
                     /locus_tag="ACGI5H_003726"
     CDS             complement(1532..2416)
                     /locus_tag="ACGI5H_003726"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889336.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_function: GO:0016987 - sigma factor activity [Evidence
                     IEA];
                     GO_process: GO:0006352 - DNA-templated transcription
                     initiation [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-70 family RNA polymerase sigma factor"
                     /protein_id="HFG9699399.1"
                     /translation="MDTKKENNYENYICVGSSNVSNAMKMYLKEIEEYKMLSAGEEVE
                     LAKEIINSSSVAKEKFINSNYRLVVSIAKRYKRDSIDMLDLIQAGNIGLIKAVEKYDY
                     KKGYKFSTYATWWIKQSITRYIDDCENTIRIPIHLHQRINFVKKKKQELLNVLLREPT
                     IDEIADACGLEVDKVLELLRRDKNVVSLDTPLKEDEDSSLVEFIPSDADFKDVVIHEV
                     EQHNLKEKIEELLTGLGEQEQQVLRMRFGIDDDDPKTLEQIGKVFGVTRERIRQIEAK
                     AIRKLRHPSKLKQLKHFY"
     gene            complement(2707..3183)
                     /locus_tag="ACGI5H_003727"
     CDS             complement(2707..3183)
                     /locus_tag="ACGI5H_003727"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889335.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I restriction enzyme HsdR N-terminal
                     domain-containing protein"
                     /protein_id="HFG9699400.1"
                     /translation="MSKELVKDRVIKYLIEDLLVPQDMIDTNVELAEFEEGAEGILDI
                     VVNVKDEEDYYAPVMIVQCLDEDVELEGEVLQKQIEFLEEVDNITMSGRLVLTNGDAM
                     MYADWRGEEYDTEAALPTYDIMVKEFHEMEQQVKDLEEHHHHDENCGCGCNHHHEN"
     gene            3449..4624
                     /locus_tag="ACGI5H_003728"
     CDS             3449..4624
                     /locus_tag="ACGI5H_003728"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419970.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1002 domain-containing protein"
                     /protein_id="HFG9699401.1"
                     /translation="MKFKKQISSIVVSTMLVLGSMNLSYADGTNVVTLGANLSESQKQ
                     QMLNYFGVKKDQVLVLDVTNAEERQYLQGVATEGQLGKVTISCSYVEPTKKGNGINVK
                     TANLTWVTSSMIASTLTTAGLEDANVIAAAPYPVSGTGALTGIMKAFEDASGKKLDET
                     KKEIASEELVVTGDLGDDIGQEKATGVMNDIKTEIVKNGTKDTNQIANTINNVVNNYN
                     ITITPEQKEQIKGVMKKIADQNYDYNSMKNTLDNVSDNVNEQLKKLGESVKGSGILDT
                     IGGWFSGIGDWFSGLFSGGDKKDLGILNNTNDESLGSDAVINSTEGVQINPQNNTNSN
                     NDSDTNSSKNDTSSNNENNDSSQTNENNTTNNSENQSNNNDSVGFFEKIKNWLSGLF"
     gene            complement(4705..5508)
                     /gene="proC"
                     /locus_tag="ACGI5H_003729"
     CDS             complement(4705..5508)
                     /gene="proC"
                     /locus_tag="ACGI5H_003729"
                     /EC_number="1.5.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419967.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004735 - pyrroline-5-carboxylate
                     reductase activity [Evidence IEA];
                     GO_process: GO:0006561 - proline biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pyrroline-5-carboxylate reductase"
                     /protein_id="HFG9699402.1"
                     /translation="MKKIGFIGAGNMASAMIGGIVNSKLVEPNMVIASAYSQGTLDRI
                     DANFGINTTKDSKEVTRTSDIVIVAVKPDIYDDILEEIKDFIDDNKIIVTIAAGKSIK
                     DIESIIGEDKKIVRTMPNTPALVNEAMSSLSINKNINKEDLEAVTEVFNSFGNTEVVP
                     EYLIEAVIGASGSAPAYVFLFIEAIADAAVIAGMPRPQAYKFASQAVMGSAKMVLETG
                     KHPGELKDMVCSPGGTTIEAVKVLEEEGFRASVIKAICACIEKSKKMSE"
     gene            complement(5548..6138)
                     /locus_tag="ACGI5H_003730"
     CDS             complement(5548..6138)
                     /locus_tag="ACGI5H_003730"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427434.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="XRE family transcriptional regulator"
                     /protein_id="HFG9699403.1"
                     /translation="MVLNKDIGAKIKQLRTQKQMTLKDMSEKTNLSIGFLSQLERGLT
                     SVATDSLGKIASVLDVELTYFFMKPKEHKRAVLRSYEKEVFDVENSTFIHYHLSSSLK
                     EKTMLPRLIEILPSKSSEEICCYVHEGEEFVYVLEGTLTVFLGDEQIEMYPGDTIHYN
                     SEKNNHNWVNYTNKVVKILVVSIPNPFEKSDAVKEA"
BASE COUNT         2244 a         1143 c          750 g         2656 t
ORIGIN      
        1 acctcacttt aattgttttt tgatacactt tttaatgatt ttatcacatt ttatcacatt
       61 taatatatta tataatgctg tggtgaacaa tttattaatc acctataata atgttaacaa
      121 atgtaattat ttaaaacaat tatttagaag gttttatatt taattttaaa taacatattt
      181 aagaaccgta agtcttaact tttatcattt ttgaggttgt cgttcacata agttcgctac
      241 tacctatgca gttctcttat gaacttctta cactttcatg taagcacaga ctatatctta
      301 tccttcagca ttatccgtta aggtctaccc acttccacta ccaatagctt gtagtgtact
      361 tccctcaaga ggaatagtcg ttgaagtttc tcctattcgg agtttacctg ctgattgccc
      421 attttaaagt acttaggatt taaccttata ccatctaacc aattttttct actttcgtaa
      481 ctttcacact taggtttatt tcatccttat gttttagttt gattagcttt aggggtttcc
      541 agcaattcaa gtagtattgg ataggttcta tcctatctct acatataggt ttccctatat
      601 gctgactatt ttagctacta actcatgact aaagtcacga gtgtgcgtag ctatttttta
      661 atcaatattt tagtaaattt tacggtaagt aaaaacctct ctccttcaaa tcctatagca
      721 aatatactta caagttgctt tgagaaaata actcctaata tagctacaac tatgcatata
      781 ccaactatta tatttaaaac attgtttaaa aactttagtg cttgcttttc accttgttta
      841 ctacttatat cttgatacat tggaataaaa gtagtaacta tagcagtacc tattgctgca
      901 aatataatat ttggtatatt catagctgtt aaataactct ctgtatataa gcctgtacca
      961 taaattgatg ataatactaa ttctctaccc attccaagaa tcttagagat tatagtaact
     1021 atcatcaaat aaaaagttgc tttagctacc ttgctcattt tatcactcca cttctaacat
     1081 acctcttttt aatcaagtaa aatttagctc attagatata attctatcaa ctaatttgcc
     1141 ttgcttagcc ctatcaaaat ataattaaca cctatttctt aatatatcac aaactacatt
     1201 attcttcata tttttttatt tctccaataa gttttacatt tttcctatat aaattgtata
     1261 gcttcaatta tattcaaaga aatggagttg ctacccgata actttaaaag taaaaaacag
     1321 attttattat ctttttaaac tatattctaa catattttgt ccatattgag aaattttact
     1381 aaactattat gtactttatt aaataaataa aataacagca cacctataaa atacaagtgt
     1441 actgttcata aacagatttt ataaaaaaat aattcctaag tagagattaa catgctttct
     1501 catactctca tatataatgt gtctaaaaat attaataaaa atgctttaat tgttttaact
     1561 tacttggatg tcttaatttt cttattgctt tagcttctat ctgtcttatt cgttctctgg
     1621 taactccaaa tacctttcca atctgttcta gtgttttagg gtcatcatca tcaattccaa
     1681 atctcattct taaaacttgc tgttcttgct ctccaagacc tgtaagtagt tcttctatct
     1741 tttcttttaa attatgctgt tcaacttcgt gtattacaac atctttaaaa tcagcatctg
     1801 atggtataaa ttcaactaaa ctactatcct catcttcttt taatggagta tccaaagata
     1861 caacattttt atctcttctt aataattcca acactttgtc aacttctaag ccacatgcat
     1921 ctgcaatctc atctatagtt ggctctctta ataatacatt taaaagttct tgtttctttt
     1981 tctttacaaa atttattctc tgatgaagat gtataggtat cctaatagta ttttcgcaat
     2041 cgtcgatata tcttgttata ctttgtttta tccaccaagt tgcataagtg ctaaatttgt
     2101 atcctttttt ataatcgtac ttttctacag cttttataag tcctatattt cctgcttgaa
     2161 ttaaatccaa catatcaata ctatctcttt tatatctctt tgctatgctc actaccaacc
     2221 tataatttga atttataaat ttttcttttg ctactgaaga tgagttgatt atttccttag
     2281 ccagctctac ctcttctcct gctgacaaca ttttgtattc ctctatttcc tttaaataca
     2341 ttttcatcgc attcgataca tttgatgaac ccacacaaat ataattttca taattatttt
     2401 cttttttagt atccataatc aaaccccttc tattcataga atttgctaaa acaaaaataa
     2461 ataatttaaa cctacataat ctacaattac ataatatccc attctttaaa tgaattgttt
     2521 tgtatattat gtatacaaat ttataaaaac tatacctata atattattct acttctaaca
     2581 gcaatatcct ccttatatat ataatttatt ttattatatg ttgttatatt cttagttttt
     2641 tgaatgatat atgtctaaaa aaagactgtt tactaaacag tcttttttta tatatatgct
     2701 caatatttaa ttttcatgat gatgattaca tccacatcca caattttcat catggtgatg
     2761 atgttcttct aaatctttta cctgttgttc catttcatga aactctttta ccattatatc
     2821 ataagttgga agagctgcct cagtatcgta ttcttcccct ctccaatcag cgtacatcat
     2881 agcatctcca ttagttaaaa ccaatctacc tgacatagtt atattatcca cttcttctaa
     2941 aaattctatt tgtttttgta aaacttctcc ttctaactcc acatcttcat ctaaacattg
     3001 cactatcatt acaggtgcat aataatcttc ttcatcttta acatttacaa caatatctaa
     3061 aattccttct gcaccttctt caaattctgc caactcaaca tttgtatcaa tcatatcttg
     3121 aggtactaat aaatcttcta ttaaatattt tattactcta tcttttacta attcttttga
     3181 catttatttt tctccttccg attctataac attatcataa tcatttctat attatagtat
     3241 actacattaa ttgttttttc aatctcttac aaaaattatt ttttattatc ttccttatat
     3301 tccctttttt attacaaagt tgtaatcgca ttgatttaaa aaatagttta tatttagtat
     3361 aatagaaatg tagcacatat ttttattcaa tatattaata aaaaaatata ttgaaaatgt
     3421 aatgtatgtt aaatctagga ggaatattat gaagtttaaa aaacaaatta gttctattgt
     3481 tgtgtctact atgcttgtac ttgggagtat gaacctttct tatgcagacg gtacaaatgt
     3541 agttacactt ggagctaact tatcagagtc tcaaaagcag caaatgctta attactttgg
     3601 agtaaaaaaa gaccaagtct tagttttaga tgtaacaaat gcagaagaaa gacagtattt
     3661 acaaggtgtt gcaacagagg gtcaacttgg aaaagttact atctcttgct catacgttga
     3721 acctactaaa aaaggaaatg gaattaatgt taaaacagca aacttaactt gggtaactag
     3781 ttcaatgatt gcttcaaccc ttacaacagc tggtcttgaa gatgcaaatg ttattgctgc
     3841 tgctccatat cctgtaagtg gtactggagc attgacagga atcatgaaag catttgagga
     3901 tgcttcagga aagaaacttg atgaaactaa gaaagaaatt gcttctgaag aattggtagt
     3961 tacaggtgac ttaggagatg atatagggca agaaaaagca acaggtgtaa tgaatgatat
     4021 aaaaacagaa attgtaaaga atggtacaaa agataccaat caaatagcaa atacaataaa
     4081 taatgttgta aataattaca atattactat tacaccagaa caaaaagaac aaattaaagg
     4141 tgtaatgaaa aaaatagctg accaaaatta cgattacaat agcatgaaaa atacactaga
     4201 taatgtatca gataatgtaa atgaacaatt aaagaaatta ggtgaaagtg ttaagggttc
     4261 tggtatacta gatactattg gtggatggtt tagtggaata ggagactggt tctctggttt
     4321 attctcaggc ggagataaaa aagatttggg aatcttaaat aatactaatg atgagtctct
     4381 tggctctgat gctgtaataa attctacaga aggtgttcaa ataaatccac aaaataatac
     4441 taattctaac aatgatagtg atacaaatag ctcaaaaaat gatacttcaa gtaataatga
     4501 aaataacgat agttctcaaa caaatgaaaa caacacaaca aataattcag aaaatcaatc
     4561 aaataataat gactcagttg gtttctttga aaaaataaaa aattggcttt caggcttatt
     4621 ttagaaatta aacaaataaa aagaattgcc taaaatggaa attttctata aaaggcaatt
     4681 ctctttattt acaataaatt tttattactc actcattttt ttagattttt ctatacatgc
     4741 acatattgct tttatcacag aagctctaaa accttcttct tcaagtactt taactgcttc
     4801 tatagtagtt ccaccaggtg aacataccat atcttttaat tcaccaggat gttttcctgt
     4861 ctcaagtacc atttttgcag aacccataac agcctgtgat gcaaacttat atgcttgtgg
     4921 tcttggcatt cctgcaatta ctgctgcatc tgctatagct tctataaata aaaatacata
     4981 tgctggtgca gaaccacttg caccaattac agcttctata agatactctg gtactacctc
     5041 agtatttcca aaagaattaa atacttctgt aactgcttct aagtcttctt tgtttatatt
     5101 tttatttatc gaaagagaag acatggcttc atttacaaga gctggagtat ttggcatagt
     5161 tctaactatt tttttatctt ctcctataat agactctata tcttttatag attttcctgc
     5221 tgctattgta actataattt tattgtcatc tataaagtct tttatctctt ccaaaatatc
     5281 atcatatata tctggtttaa cagctacaat tactatatca gaggttctag ttacttcctt
     5341 cgagtctttt gtagtattta ttccaaaatt tgcatctatt ctatcgagag ttccttgact
     5401 atatgctgat gctataacca tattaggttc aactaatttt gaatttacta ttccccctat
     5461 catagcgctt gccatatttc ctgcacctat gaatccaatt tttttcactt tagtacctcc
     5521 ttattgacta atagtaatcg ttaaaattta agcttcttta actgcatcag atttttcaaa
     5581 tggatttggt atacttacta ccaaaatttt cactacctta ttagtatagt tgacccaatt
     5641 atgattgttc ttttcactat tatagtgtat tgtgtctcct ggatacattt ctatttgttc
     5701 atctcccaaa aacactgtaa gagtaccctc taatacatac acaaattcct caccttcatg
     5761 tacgtaacaa caaatttcct cactactctt acttggaaga atttcaatta atcttggtag
     5821 cattgttttt tcctttaaac tagatgataa atgataatgt ataaatgttg agttttctac
     5881 atcaaatact tctttttcat aacttcttaa tacagctctt ttatgctctt ttggcttcat
     5941 aaaaaagtaa gttaattcta catctagtac acttgctatt tttcctaagg aatctgttgc
     6001 cacacttgtt aatcctcttt caagttgtga taaaaaacca attgacaagt ttgttttttc
     6061 actcatatcc ttcagcgtca tttgcttttg agttctgagt tgctttattt ttgctcctat
     6121 gtccttattc aaaaccatca cccctaaata attttaattt tttcataata taaatacaaa
     6181 aatataaata taggtactga acccatcttt atttcattta aaaaaatttt tataagtatt
     6241 actataattt atcaatcttt ttttgtctac atttttacga ttatttacga tttatttttc
     6301 acatatgtat atttaatctt gccaactaaa gatacatttt ttataagcat ttactcttta
     6361 tataataaaa cttaagttgt tcatgtagtc ttcttctggt ttaattatta aaatttcaaa
     6421 ttatattatt atttctacac attattacat cctttagtac aattataaca taattttaca
     6481 atttaatgat atctattcaa tgtctttttt tactctacaa catattttat tttagagttt
     6541 aatactatat atatttttta tatacagcct tgtcattttt tagattgtca agagttattg
     6601 aagtatttta tgtagattta gattttattt cctaatttct catttaacaa gaattgctta
     6661 tgataaaaaa taatatcatc tcaataagat tcttgtaaat atatctatat tctaaatata
     6721 atttcttttt ttgtcaaaat ttcttcattc tttaataatt aatttattac ttataaaata
     6781 aactaattat cta
//
LOCUS       DAYAOO010000148         6657 bp    DNA     linear   BCT 12-OCT-2024
DEFINITION  TPA_asm: Clostridioides difficile isolate ST8-SSI-h139-18
            SAMN40601845-rid21577343.denovo.152, whole genome shotgun sequence.
ACCESSION   DAYAOO010000148 DAYAOO010000000
VERSION     DAYAOO010000148.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN40601845
            Sequence Read Archive: SRR28438827
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 6657)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6657)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-MAY-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-MAY-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002157583.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002157583.1
            Genome Coverage       :: 163x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/11/2024 16:19:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 4,038
            CDSs (total)                      :: 3,963
            Genes (coding)                    :: 3,930
            CDSs (with protein)               :: 3,930
            Genes (RNA)                       :: 75
            rRNAs                             :: 6, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 60
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 33
            CDSs (without protein)            :: 33
            Pseudo Genes (ambiguous residues) :: 0 of 33
            Pseudo Genes (frameshifted)       :: 7 of 33
            Pseudo Genes (incomplete)         :: 25 of 33
            Pseudo Genes (internal stop)      :: 11 of 33
            Pseudo Genes (multiple problems)  :: 8 of 33
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6657
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN40601845-rid21577343.denovo.152"
                     /isolate="ST8-SSI-h139-18"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Denmark"
                     /collection_date="2018"
                     /collected_by="Statens Serum Institute"
     gene            211..1536
                     /gene="cdeA"
                     /locus_tag="ACGI5H_003731"
     CDS             211..1536
                     /gene="cdeA"
                     /locus_tag="ACGI5H_003731"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902537.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux MATE transporter CdeA"
                     /protein_id="HFG9699404.1"
                     /translation="MENLFTRKFTTFEFLKFVSPAIISMIFISLYTIIDGIFVSTLVG
                     SDALASINIVLPIINLVCGFGIMMATGGGAIVSIRMGENRQDEANSTFSFIVLFSLIV
                     GILFTVISYFFIKEISILLGATDKLLPYCITYGKVMILCTPFYILKFIFEYFARTDGN
                     SKFSLFLSVIGGVTNIILDYVFIKYFGMGLLGAAVATAIGIILTCVLGIIYFLSNKST
                     LKLRKPKTDFRLIRDTMINGSSEMVTELSTGITTFLFNVVALKLAGENGLAALTIVLY
                     AHFLMTSVYLGFAAGVSPLISYNFGAENSDKLKETFKHSLKFIFVSSLLVFIFALVFA
                     PFIVRVFVSPDNTVFKLALQGLKIFAFAFLFVGINIFASGFFTAFHNGKISAIISFSR
                     AFVFIIIGIIILPPMLNMTGLWLTVPFAEVITIFISILFIKKYKCRYKY"
     gene            complement(1631..2425)
                     /locus_tag="ACGI5H_003732"
     CDS             complement(1631..2425)
                     /locus_tag="ACGI5H_003732"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420000.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HFG9699405.1"
                     /translation="MNELKPYIKFFNKNTKLYIIIFMIVGIVMNILPVFILKIFGEAS
                     KTNLSTIVNPILTYITILLFVYGVNIANKDFSGALSIRADRKSCIKAIVIDLIILSFV
                     ISILGIVLIFLSKLFIEIITGYSIELSVLLKRDMIWTSISALIDPSTSSMPLTYLNYF
                     VQICINEICIGFIGVLLGAFTYRVRKVTSITILIGLPILMIIYIVNFATKNMHKMLLY
                     LEKIIYSFQNPFILFGTKVGIIVICIIFIILLLRKAPIKEYANDLL"
     gene            complement(2426..3301)
                     /locus_tag="ACGI5H_003733"
     CDS             complement(2426..3301)
                     /locus_tag="ACGI5H_003733"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896447.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HFG9699406.1"
                     /translation="MSSSIKIENLSHSFKKQNIFNNMSLSFEKNKIYGLLGKNGAGKT
                     TLLNIMVNQLIQNEGEIEILGKNPKEDIKVLEEVCIVREKEFYSPDFKVGQIFEFSSS
                     FYKSYDKGLEEELCKYFDLNTKKKYKQLSRGMKTILSNIIGICSNSAITIFDEPTIGL
                     DAVNRQEFYNIILDSYIKNPRTIIISTHLIDEIDDLLEHVIILNEGKIIIDEEIDVIK
                     QKAHYITGNKEELEKLECIKNIKPKKAFGNAVAYFYYGDFSESDEKILKNSNIDVGYI
                     GLQDMFVNMTKKEEL"
     gene            complement(3305..3673)
                     /locus_tag="ACGI5H_003734"
     CDS             complement(3305..3673)
                     /locus_tag="ACGI5H_003734"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419996.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HFG9699407.1"
                     /translation="MKLVLNNEEPIFIQIARAIEDEILSNGIKEEEQVPSTTELSKLY
                     KINPATVLKGINILVDKNILYKKRGIGMFVSDGAKTIIKEARKENFKHNFVKNLLQEA
                     NKLEINREELVDIIINFKED"
     gene            complement(3856..4515)
                     /gene="deoC"
                     /locus_tag="ACGI5H_003735"
     CDS             complement(3856..4515)
                     /gene="deoC"
                     /locus_tag="ACGI5H_003735"
                     /EC_number="4.1.2.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439345.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0004139 - deoxyribose-phosphate aldolase
                     activity [Evidence IEA];
                     GO_process: GO:0009264 - deoxyribonucleotide catabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="deoxyribose-phosphate aldolase"
                     /protein_id="HFG9699408.1"
                     /translation="MKHILKTVDHTILKATTTWEDIKILCDEAVDMSVASVCIPPSYV
                     KRASEYLKGKIKICTVIGFPLGYQTTATKVFEAKDAIENGADEVDMVVNISDIKNKDY
                     DNIGKEIKEIKKAIGDKVLKVIIETCYLDEDEKIKMCEIVTMSGSDFIKTSTGMGTGG
                     ATLEDIKLMKEHVGKNVKIKAAGGVKSISDAEKFIEAGAERLGTSSICKILKNEDTTD
                     Y"
     gene            complement(4551..5738)
                     /gene="murJ"
                     /locus_tag="ACGI5H_003736"
     CDS             complement(4551..5738)
                     /gene="murJ"
                     /locus_tag="ACGI5H_003736"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896445.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0009252 - peptidoglycan biosynthetic
                     process [Evidence IEA];
                     GO_process: GO:0034204 - lipid translocation [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="murein biosynthesis integral membrane protein
                     MurJ"
                     /protein_id="HFG9699409.1"
                     /translation="MKQEPCDFSHGRFRTGIIFIGITSVMSAFLQIKENFIVVGFGSI
                     PYNIVIIISIMLSTIFGPYILPIGAVVAMVVQLLFYMFFVKKTNYKYLYYLNFKDDSL
                     IKLLALLSPVFIGVAVNQVNSLVDTTLASTLVKGSIPALTYADRLNGFVTGTFTASIV
                     SVMYPMLSKLSAENNQKKFTSSVKSSINMIIISMIPISVASIFFATPVVRIIFERGAF
                     DARATQMTATALIFYAVGMTAFGLRDILGKVFYSLQDTKTPMVNGIISVGVNIVLDLV
                     LIKPMAHGGLALATSSSSIACILLLFLNLKRKVGYFGQDKIIKATLKSVVASLIMGVL
                     SYFTYKFIFGILGVGTFNEFVSLAISVIVGGGIYTLLMIIFKVEEVDMILNIAKRKLH
                     LKK"
     gene            complement(5815..>6657)
                     /locus_tag="ACGI5H_003737"
     CDS             complement(5815..>6657)
                     /locus_tag="ACGI5H_003737"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888399.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-guided endonuclease TnpB family protein"
                     /protein_id="HFG9699410.1"
                     /translation="FKEKAGFPKFKSKKINRFSYKTNFTNGNIMYCGQHIKLPKLGMV
                     KIRDKQVPKGRILNATISKEPSGRYYVSLCCIDVDIEVFENTNNHIGLDLGIKEFCIS
                     SCGEFIENPKYLKKSLNKLAKLQRELSRKTIGSLNRNKARLKVARLQEHIANQRNDFL
                     QKLSTKLIKENDIICIEDLQVKNMIRNRKLSRLISDVSWSEFIRQLEYKANWYGRQIV
                     KVGKFFASSQICNKCGYKNEEVKNLNIREWICPSCNETHDRDINASINILKEGLRLIT
                     IQNK"
BASE COUNT         2195 a         1042 c          730 g         2690 t
ORIGIN      
        1 ttaagattat atacatatat ttctaaagat tttcttaaga aacagttaga ttttactaat
       61 ataagtttat taattagcat tatactaatt tatcttaata tgattttttg ttgattttaa
      121 gctgtttatc gtataaataa aatttttctt gactatatag ttactatata gcttattata
      181 tatagagagt aataaaagga ggtaaaattt atggaaaatt tatttacaag aaaattcact
      241 acttttgaat ttctaaaatt tgtttctcct gcaattatat ccatgatatt tatatctttg
      301 tacacaataa tagatggcat ctttgtatcg acattagttg gttctgatgc tcttgctagt
      361 ataaatattg tactacctat aattaacctt gtttgtggat ttggaataat gatggcaact
      421 ggtggaggtg ctatcgtttc tatacgtatg ggtgaaaata gacaggatga agccaactct
      481 acattttctt ttatagtttt gttttcattg attgttggga ttttattcac agtaatctca
      541 tatttcttta tcaaagaaat atctattttg cttggtgcaa cagataagtt attaccatat
      601 tgtataactt atggtaaagt tatgatttta tgtacaccat tttatatttt aaaatttata
      661 tttgagtact ttgcaagaac tgatggaaat tctaaattta gtttatttct atcagtcatt
      721 ggtggtgtaa caaatataat attggattat gtatttatta aatattttgg aatgggtctt
      781 ttaggagctg cagttgcaac tgctataggt attattttaa cttgtgtttt aggtattatt
      841 tacttcttat ctaataaatc tacactaaaa ttaagaaaac caaaaaccga ttttagactt
      901 ataagagata ctatgataaa tggttcttct gaaatggtta cagaattatc tacaggaatt
      961 acaacattct tatttaatgt agtagcttta aaattagcag gagaaaatgg acttgctgct
     1021 cttactatag tattgtatgc tcatttttta atgacatcag tctatctagg attcgctgct
     1081 ggagtgtctc cattaataag ctataatttt ggtgctgaaa acagtgataa attaaaagaa
     1141 acatttaaac attctctaaa atttatattt gtttcttctc ttttagtgtt tatttttgct
     1201 ttagtatttg caccatttat tgttagggtc tttgtaagtc cagataacac agtatttaaa
     1261 ctagccttac aaggattaaa aatatttgca tttgcttttt tgtttgttgg tataaatata
     1321 tttgcatcag gattttttac agcatttcac aatggaaaaa tttcagctat tatatctttt
     1381 agtcgtgcct ttgtttttat aatcatagga atcataattc ttcctcctat gttaaacatg
     1441 actggattat ggcttacagt tccatttgct gaggttataa ccatatttat atctattcta
     1501 tttataaaaa aatataaatg tagatataag tattaaaaat taatacttaa aatcaacatt
     1561 tattaaaact aataaacctg ctttaaaata caaatttaca aatttgattt ttaagcaggt
     1621 tttattttag ttataataag tcatttgcat actctttaat tggtgctttt ctaagtaata
     1681 aaattataaa tattatgcaa ataactataa ttcctacttt tgttccaaat aaaataaaag
     1741 gattctgaaa tgaataaata attttttcta aatacaatag cattttatgc atatttttag
     1801 ttgcaaaatt aactatataa attatcatta atatcggtaa tcctatcaat atagtaatac
     1861 tagtaacttt tctaactcta tatgtaaaag ctccaagtaa cactcctata aaacctatac
     1921 atatttcatt tatacatatt tgtacaaaat aatttaaata agttagtggc atacttgatg
     1981 ttgaaggatc tatcagtgct gatatagatg tccaaatcat atctctcttt agtaaaactg
     2041 atagttctat actgtaacct gttataattt ctataaataa cttcgataaa aaaatcaaaa
     2101 ctatacctaa aatagaaatc acaaagctta aaataattaa atctatgaca atagctttta
     2161 tacaactttt tctatctgct cttatactta aagctcctga aaagtcttta tttgctatat
     2221 ttactccata cacaaatagc agtatagtta tatatgttaa aataggattc acaatcgtgg
     2281 ataaattagt tttagatgct tctccaaaaa tcttgagaat aaacactggc aaaatattca
     2341 taacaattcc cacaatcata aatataatta tatacaattt agtattttta ttaaaaaatt
     2401 ttatatatgg ctttaattca ttcaattaca attcctcctt cttagtcatg ttaacaaaca
     2461 tatcttgtag ccctatgtat cctacatcaa tatttgaatt tttaagtatt ttttcatcac
     2521 tttcactaaa atcaccatag taaaaataag caactgcatt tccaaatgcc tttttaggtt
     2581 ttatattttt tatacattct aatttttcta actcttcttt atttccagta atataatgag
     2641 ctttttgttt tatgacatca atttcttcat ctataataat ttttccctca tttaatatta
     2701 ttacatgctc cagtaaatca tctatttcat caatcaaatg agttgatatt attattgtcc
     2761 ttggattttt tatataacta tctaaaatta tgttataaaa ctcttgtcta tttactgcat
     2821 ccagaccaat tgttggctca tcaaatatgg tgatagctga attagaacaa atacctatta
     2881 tatttgaaag tatagttttc atacctcttg acagttgttt atactttttt ttagtattta
     2941 aatcaaaata tttgcataat tcttcttcta agcctttatc ataactttta taaaaactag
     3001 aagaaaattc aaatatctga cctactttaa aatctggact ataaaattct ttttccctaa
     3061 cgatacaaac ttcttccaaa acttttatat cttcttttgg gttctttcct aatatttcta
     3121 tctcaccttc attttgaatt aactgattta ccattatatt taataatgtt gtttttccag
     3181 ctccattctt acctaataaa ccatatatct tatttttttc aaagcttaga gacatattat
     3241 taaaaatatt ttgcttctta aaactgtgag ataaattttc tatcttaata gaactactca
     3301 tatattaatc ctccttgaaa ttaattataa tatcaaccaa ttcttctcta tttatttcta
     3361 atttgttagc ttcttgaagt aggtttttta caaaattatg tttaaaattt tcttttctag
     3421 cttcttttat aatagttttt gcaccatctg atacaaacat ccctatcccc ctcttcttat
     3481 ataaaatatt tttatcaacc aatatattta taccttttaa tactgtagct ggattaattt
     3541 tataaagctt tgaaagctct gttgttgatg gaacctgttc ttcttctttt attccatttg
     3601 atagtatctc atcttcaatt gctcgtgcta tctgaataaa tataggttct tcattattta
     3661 atactaattt cataggttcc tcctttctcc atcagttagt tactcaacta attaactata
     3721 taacttataa tatcttgaaa aatattttct gtcaatacta aataaaaaac agagggaaaa
     3781 ttccctctgt tttttgttct ttatatttat aattaaattt tgatttttgt aatcctatcc
     3841 cataagttaa aaactttaat aatctgttgt atcttcattt tttaatattt tacatattga
     3901 gctagttcct aacctttctg ctcctgcctc tataaatttt tctgcatcag aaattgattt
     3961 aactccccct gcagctttta tttttacatt ttttccaaca tgctctttca taagttttat
     4021 atcttctaaa gtagctccac ctgttcccat tccagtagat gtttttataa aatctgaacc
     4081 tgacattgtt actatttcac acatttttat tttttcatct tcatctaaat aacatgtctc
     4141 tataatgact tttaatactt tatctcctat agcttttttt atttctttta tttcttttcc
     4201 tatattatca taatctttat tttttatatc tgaaatgttt acaaccatat caacttcatc
     4261 tgctccattt tcaatagcat cttttgcttc aaatactttt gtagcagtag tttgatatcc
     4321 caaagggaac cctatcactg tacatatctt tattttacct tttagatatt ctgatgctct
     4381 tttcacatat gatggtggta tgcaaactga tgctacactc atatctacag cttcatcaca
     4441 taaaatttta atatcttccc atgtagttgt agcttttaaa atagtatggt ctactgtttt
     4501 taatatatgt ttcataaaat cctcctaaat ttataattaa tataattaga ttactttttt
     4561 aaatgcaatt ttctctttgc aatgtttagt atcatatcaa cctcttcaac tttaaaaata
     4621 atcattagta gtgtataaat tccacctcca actataactg aaatagctag tgatacaaac
     4681 tcattaaatg ttcctactcc caaaattcca aatataaatt tatacgtaaa gtatgataaa
     4741 acacccataa ttaaagatgc aactaccgat ttcaaagttg cttttattat tttatcttgt
     4801 ccaaaatatc caacttttct ctttaggttc aagaagagta acaatataca tgcaattgat
     4861 gatgaactag ttgcaagagc aagaccacca tgagccattg gttttattaa aactaagtcc
     4921 aatactatat ttacccctac agatataatc ccatttacca taggtgtttt tgtgtcttgt
     4981 aatgaataaa aaacctttcc caaaatatct cttaagccaa atgcagtcat accaactgca
     5041 taaaaaatta aggcagttgc tgtcatttgg gttgccctcg catcaaaagc acctctctca
     5101 aaaatgattc taacaacagg agttgcaaaa aaaatagaag caactgaaat aggaatcata
     5161 gaaattatta tcatatttat actggattta actgaactag taaacttctt ttgattattt
     5221 tctgcactta acttagataa cataggatac ataacagata ctattgaagc tgtaaatgtc
     5281 cctgtaacaa aaccatttaa tctatctgca taagtaagtg ctggaatgct tcctttaact
     5341 aatgttgagg ctaaagttgt atctaccaat gagttcactt gattaacagc aacacctata
     5401 aatactggtg aaagtaatgc tagtaattta ataaggctat catctttaaa gtttaagtag
     5461 tataagtatt tgtagttcgt ttttttaaca aaaaacatgt aaaagagcag ttgaactacc
     5521 atagcaacca cagcaccaat tggaagtatg tatggtccaa atatggtact taacattatt
     5581 gaaataatta ttactatatt atagggtata cttccaaatc caactacaat aaagttctct
     5641 ttaatttgta aaaatgctga cataacactc gtaataccta tgaatattat tcctgttctg
     5701 aacctcccat gactaaagtc acagggttcc tgcttcatag aattttgcat actaaaatat
     5761 gtcttactaa ttctccacag gctatccccg tagttcctac ggttcttaca tacgttattt
     5821 attttgaatt gttattagtc ttaatccttc ttttaatata tttatacttg catttatatc
     5881 tctatcgtga gtttcattac aactaggaca aatccattct cttatattta agttcttaac
     5941 ttcctcgttt ttatacccac atttattgca tatttgtgaa cttgcaaaga atttacctac
     6001 ctttacaatt tgtctaccat accaattagc cttgtattct aattgacgaa taaactctga
     6061 ccatgataca tcagaaatta agcgagatag tttacgattt ctaatcatat tctttacttg
     6121 taaatcttct atgcaaataa tatcgttctc ttttattaat ttagtagata gtttttgtag
     6181 aaaatcattt ctttgattag ctatatgttc ttgaagtctt gcaactttta atcttgcttt
     6241 atttctattt aaactaccga ttgtttttct cgataattct ctttgtaatt tagcaagttt
     6301 gtttaatgac ttcttaagat acttaggatt ttctataaat tctccacaac ttgagataca
     6361 aaattcttta attcccaaat ctaaacctat atgattatta gtattttcaa atacttcaat
     6421 atctacatca atacagcata atgatacata atatctacca cttggttctt tagatatagt
     6481 agcattaagt attctccctt taggtacttg tttatccctt atcttaacca taccaagttt
     6541 aggtagtttt atatgttgac cacaatacat aatgtttcca tttgtaaagt tagttttata
     6601 tgaaaatcta ttaattttct ttgatttaaa tttaggaaat cctgcttttt ctttaaa
//
LOCUS       DAYAOO010000149         6620 bp    DNA     linear   BCT 12-OCT-2024
DEFINITION  TPA_asm: Clostridioides difficile isolate ST8-SSI-h139-18
            SAMN40601845-rid21577343.denovo.153, whole genome shotgun sequence.
ACCESSION   DAYAOO010000149 DAYAOO010000000
VERSION     DAYAOO010000149.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN40601845
            Sequence Read Archive: SRR28438827
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 6620)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6620)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-MAY-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-MAY-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002157583.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002157583.1
            Genome Coverage       :: 163x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/11/2024 16:19:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 4,038
            CDSs (total)                      :: 3,963
            Genes (coding)                    :: 3,930
            CDSs (with protein)               :: 3,930
            Genes (RNA)                       :: 75
            rRNAs                             :: 6, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 60
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 33
            CDSs (without protein)            :: 33
            Pseudo Genes (ambiguous residues) :: 0 of 33
            Pseudo Genes (frameshifted)       :: 7 of 33
            Pseudo Genes (incomplete)         :: 25 of 33
            Pseudo Genes (internal stop)      :: 11 of 33
            Pseudo Genes (multiple problems)  :: 8 of 33
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6620
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN40601845-rid21577343.denovo.153"
                     /isolate="ST8-SSI-h139-18"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Denmark"
                     /collection_date="2018"
                     /collected_by="Statens Serum Institute"
     gene            391..1665
                     /locus_tag="ACGI5H_003738"
     CDS             391..1665
                     /locus_tag="ACGI5H_003738"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003432037.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminotransferase class V-fold PLP-dependent
                     enzyme"
                     /protein_id="HFG9699411.1"
                     /translation="MQFMDVSKYIEGANLKVKTKSGETVKRIYFNNSATPLVLKNVVD
                     NLNCEIPLLTYINAPGIISEKNTLKYENVRSTILKLIDGDEEKDSVIYVKNATEGINF
                     LAKFFKDENPDKFVITTAMEHMANYLPFKVNFPTKVVGITEKGELDLCQLENILKNYA
                     GNVSLVTVTGASNVTGITTPIYEIARIAHKYGAKILVDIVQVIQHKPFSMMPHECDEH
                     IDFVVFSAHKCYSPLNGGALVGPKKFFEKFNPVLYGSGSTKFVNDNKILYANVPQRFE
                     AGYPEYFGTLAMGKALNTLNKIGLNRISKYERELFLYAKEEMSKIPNIIIYGDKSNNV
                     IIPNISFNISNMYYKDVAKYLVDNFGIETGAGVVGADIYVQKLLGISPKEAYVRFMRE
                     NPVGLVRISLGMYNTFDEVDSFIHAIKTLAFK"
     gene            complement(1872..2198)
                     /gene="trxA"
                     /locus_tag="ACGI5H_003739"
     CDS             complement(1872..2198)
                     /gene="trxA"
                     /locus_tag="ACGI5H_003739"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439893.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0015035 - protein-disulfide reductase
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin"
                     /protein_id="HFG9699412.1"
                     /translation="MYIMVKIVNNNEFINEVENKDGLVVVDFFATWCGPCKMLSPIYE
                     ALGNEMVEKANFLKVDIDQSIELAQKFEVSTVPTMLIFKDGKPVDRLIGFMPKENLKN
                     KIESYM"
     gene            2456..3208
                     /locus_tag="ACGI5H_003740"
     CDS             2456..3208
                     /locus_tag="ACGI5H_003740"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003432043.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TrmB family transcriptional regulator"
                     /protein_id="HFG9699413.1"
                     /translation="MDNIINELQNIGFTKYESQIYISLLKESPLTGYEISKLSGVPQS
                     KVYENITKLLNNNIIINVGTDPIKYIPINPNELLKNKKKEFDNSMDNLKNSLQILNKS
                     KSVEYVLNIKGDKNILKKAIEMIKNAKQEIIISCPYEEILELKKELLIAYKKNINIEI
                     LLLENKSLKGLDNIHIHGGNKTTLENKMLYKGIILIVDNDEILTGNLSEGSEAISIWT
                     KNSNILYIGVQYIKHEIYISEQIKGGYKNEQN"
     gene            3195..4076
                     /locus_tag="ACGI5H_003741"
     CDS             3195..4076
                     /locus_tag="ACGI5H_003741"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003432046.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0016853 - isomerase activity [Evidence
                     IEA];
                     GO_process: GO:0009058 - biosynthetic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PhzF family phenazine biosynthesis protein"
                     /protein_id="HFG9699414.1"
                     /translation="MNKIKIKQVDAFTTIPFGGNPAGVVTDTSNISDEIKQNVAKEMN
                     LSETAFVSESNIADFKVQFFTPGLEVDLCGHATIGTFHALLEEGKLNTNKSIFYQETK
                     AGVLSVELKKINNENIFMMEQNTPEFENLDNCRKELAQMIGVHEDRLLEYPIIKVNTG
                     LWWLVFGLKSLDDLKNISPDLNKIKKFSGDNNIIGITPFCIETIDKKCDYHLRSIAPY
                     VGVTEDPVCGTGNACVSSYIVHHNILDKTSFIGEQGNFINRPGKVYVNITRENNNITS
                     VKIGGSAYTVLSGEIMY"
     gene            complement(4302..5657)
                     /locus_tag="ACGI5H_003742"
     CDS             complement(4302..5657)
                     /locus_tag="ACGI5H_003742"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004453772.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide MFS transporter"
                     /protein_id="HFG9699415.1"
                     /translation="MSSTVKKKGKFPMGFYICSTTFSFERAAYYASKYLIYIFLTTAI
                     VHGGLGIDKGQAAIMQANLVAFTYLAPIIGGYISDRWIGARYTIPIGMLIMGVGYYLG
                     SIATTVSMVNAMIILVSIGTAFFKGNVSAVNGQLFDSQEELDTAFSVQYSFVNIGSFI
                     GTIAVGILYLKTFAKNGVLGFSQCFFIAAVLCVIGAIWFIYGWRFLGNAGKRPFKEGV
                     VAEKIEEKDKSPLTSMDKKRIWAIILISFFSVIFWVFWYLTYLAVYDYGAAFVNMNVG
                     GFDVPLAWFDSLNSLVCIVLGPVLGALWFKLASRPQGDMSLFKKTGLGLIFLGLAFLM
                     LVGAEFSRGVGAPETAKASILWIIMFGILLSLGEMLFSPLGNSFVSKYAPKKLLGVLM
                     GVWTFATFIAGKGYGYIYAFTLKFDMIKVYTIIPVILFVAAILLFLSDKTLSRLVEDD
                     K"
BASE COUNT         2544 a          952 c          828 g         2296 t
ORIGIN      
        1 tttctaatta tatacaatat attttccatt atgttctaat caatttcttt actattttta
       61 caactttatt agtcatattc ataattattt ctaattagtg tttaacattt tatgtaaaat
      121 ttataaaaaa atgtatataa attaaaataa gtgactatac taaaaatatg atacggataa
      181 acaataagtt caacctatct cccccaaaat caagtgagct acagtttccc ccaactgtag
      241 ctcattttcg tgtaatttaa taaacatctc aacaagaatt aattaacaaa accccttata
      301 aaaacataac atatattaaa caagctcttg attaaaactt gagctttttt aataaaaaac
      361 agaatagttt attagataag gggttttttt atgcaattca tggatgtatc taaatacatt
      421 gaaggtgcaa accttaaagt taaaactaaa agtggtgaaa ctgttaaaag aatatatttt
      481 aacaactctg ccactccatt agttttaaaa aacgtagtgg ataacttaaa ctgtgagatt
      541 cctttgctta cttatattaa tgctccagga ataatctcag aaaaaaatac tttaaaatat
      601 gaaaatgtac gctctactat cctcaaactt attgatggag acgaagaaaa ggattctgtt
      661 atttatgtca aaaatgctac agaaggaata aacttcttag caaaattttt taaagatgaa
      721 aatccagata aatttgttat taccacagca atggagcata tggctaatta cctgcctttt
      781 aaagttaatt ttcctacaaa agttgttgga attacagaaa aaggagaact tgatttatgt
      841 caattagaga atatacttaa aaattatgct ggtaatgtat ctctcgttac agttacagga
      901 gctagtaatg tcacaggtat aaccactcct atatatgaaa tagcaagaat agctcataag
      961 tatggtgcaa agatattggt ggatattgtg caagtaattc agcataaacc tttttcaatg
     1021 atgccacatg aatgtgatga gcatatagat tttgttgttt ttagtgctca taaatgttat
     1081 tctccactaa atggaggagc tctggtagga cctaaaaaat tctttgaaaa atttaatcct
     1141 gtactatatg gctcaggttc taccaaattt gtaaatgata acaaaatact atatgcaaac
     1201 gtaccccaac gttttgaagc aggataccca gagtattttg gaactcttgc aatgggaaaa
     1261 gcactgaaca ctttaaataa aattggtcta aacagaattt caaaatacga aagagaatta
     1321 tttttatatg ctaaagaaga aatgagtaaa atacctaata taataatata tggagataaa
     1381 tcaaataatg taattatccc aaatatatct tttaatataa gtaatatgta ttacaaagat
     1441 gtagcaaaat atttagttga taactttgga atagaaactg gagctggagt agtaggtgca
     1501 gatatttatg tacaaaaatt attaggtata agtccaaaag aagcatatgt cagatttatg
     1561 agggaaaatc ctgtaggtct tgttaggata agcttaggaa tgtacaatac ttttgatgag
     1621 gtggatagct ttatacatgc tattaaaact ttggctttta aataagtttt ttctattctt
     1681 ttttatcaat aaatagagag tagttttgtt ttcacaaaaa agcaaattat atcaacagtc
     1741 aatttcatta gcaattagac actcatttgt aactatacaa actattttac actatacaaa
     1801 caaaaaactc attacaatga gtttttttgt ttatatatga gatttatttt aattacttca
     1861 atttacttta attacatata tgattcaatt ttgtttttta aattctcctt aggcataaaa
     1921 cctattaatc tatctacagg ttttccatcc ttaaatatta gcatagttgg tactgtagat
     1981 acttcaaatt tctgagctaa ttctatactt tggtctatgt ccaccttcaa gaagtttgct
     2041 ttttcaacca tctcatttcc taaagcttca tatattggtg atagcatctt acaaggtcca
     2101 caccaagtcg caaagaaatc tacaactact aaaccatctt tattttctac ttcatttata
     2161 aattcattat tatttactat ttttaccata atatacatct cctttattat cttcttgata
     2221 ttaatatact acgacctata taacagttca attaggcact tttttgtaac cgcctatttt
     2281 taatagattt aatattatga taaatagatt tataagatta aatatttata agactaaata
     2341 tttctaatat attttatttt tttcttaata tagttgacat tttttccctt aaattataaa
     2401 atcaaattaa taactacata ggtagttact aatcttttat caaaggagtt tctatatgga
     2461 taatattatt aatgaattac aaaatatagg atttactaaa tacgaatctc aaatatacat
     2521 atcattatta aaggaaagcc ctttaacagg atatgaaata agtaaattat caggtgtacc
     2581 acaatcaaaa gtctatgaaa atataacaaa gctattaaac aataatataa ttatcaatgt
     2641 tggaactgac cctattaagt acataccaat aaaccctaat gaattattaa aaaataagaa
     2701 aaaagaattt gacaattcta tggataatct aaagaatagc ttacagatat taaataaaag
     2761 taaaagtgta gaatacgtat taaacataaa aggagataaa aatatattaa aaaaagcaat
     2821 agaaatgata aaaaatgcaa aacaagaaat tataatttct tgcccttatg aagaaattct
     2881 tgaattaaaa aaagaactcc taattgctta caaaaaaaat attaatattg aaatactact
     2941 tttagaaaac aaaagtctga aaggtcttga taatattcat attcatggag gtaataaaac
     3001 tacacttgaa aataaaatgc tttacaaagg aattattttg attgtagata atgatgaaat
     3061 attgacagga aacttatcag aaggcagtga ggccatttca atttggacaa aaaactctaa
     3121 cattttatat attggagttc aatacataaa acatgaaatt tatatttcag aacaaataaa
     3181 aggaggttat aaaaatgaac aaaattaaga ttaaacaagt tgatgctttt acaactatac
     3241 cttttggtgg aaatcctgct ggtgtcgtta ctgatacctc taacatttct gatgaaatta
     3301 agcagaatgt ggctaaagaa atgaatttat cagaaactgc atttgtttca gagtcaaata
     3361 ttgcagattt taaagtacaa tttttcacac caggtttaga agttgattta tgtggtcatg
     3421 caacaatagg tactttccat gcacttttgg aagaagggaa gcttaatact aataaaagta
     3481 tattttatca agaaacaaaa gctggtgtat tatctgtaga gcttaagaaa ataaataatg
     3541 aaaatatatt tatgatggaa cagaatacac ctgaatttga aaatttagat aattgcagaa
     3601 aagaacttgc acaaatgata ggtgtgcatg aagatagact tcttgaatat cctattataa
     3661 aggtaaatac tggactttgg tggcttgtat ttggtctaaa atctttagat gatttaaaaa
     3721 atatctctcc agatttaaat aaaatcaaaa aatttagtgg tgataataat ataattggta
     3781 taactccatt ttgtatagaa actatagata aaaagtgtga ctaccattta agatctatag
     3841 caccatatgt tggagttaca gaagaccctg tatgtggaac tgggaacgct tgcgtatcat
     3901 cttatatagt acatcacaat attttagata aaactagttt tattggtgag caaggtaact
     3961 ttataaacag acctggaaag gtatatgtaa atataactag agaaaacaat aacataactt
     4021 ctgtaaaaat tggaggaagt gcttatactg tcttaagtgg tgaaattatg tattaatccc
     4081 atacctaata aaaacaaata aaaatactag ctaactaaag ctagtatttt tatttgttat
     4141 ttttatttaa taatcatact ctaacaaata ttataattat atatatcata atattgtatt
     4201 tagaagtaaa attttatttt tattattaat tagttataaa tcaatctaat acaacataat
     4261 tacagtagat taacctataa aacataataa ttgcttactg attatttatc gtcctcaaca
     4321 agtctactta atgtcttatc agataagaat aataatatcg ctgcaacaaa tagtattact
     4381 ggaattatag tatatacttt aatcatatca aatttaagag taaatgcata tatatatcca
     4441 tatcctttac cagctataaa agtagcaaat gtccatactc ccataagaac acctagaagc
     4501 ttcttaggtg catacttact tacaaaagag ttaccaagtg gtgagaataa catttcacca
     4561 agacttaaaa gaataccaaa catgattatc catagtatac tagctttagc agtttcagga
     4621 gctccaactc ctcttgaaaa ttctgcacca acaagcatta agaatgcaag acctaagaat
     4681 attaatccaa gacctgtctt tttaaataaa ctcatatctc cttgtggtct actagcaagt
     4741 ttaaaccata atgctccaag aactggtcct aatactatac atacaagtga atttaatgag
     4801 tcaaaccaag caagaggaac atcaaatcct ccaacattca tgtttacaaa tgctgcacca
     4861 taatcataaa ctgcaagata agttagatac cagaataccc agaaaattac agagaagaat
     4921 gatataagta taatagccca aattctcttc ttatccatgc ttgtaagagg agacttatct
     4981 ttttcttcaa ttttttcagc aactacacct tctttaaaag gtctctttcc tgcattccca
     5041 aggaatctcc atccatatat gaaccatatt gcacctatta cacaaagtac agctgctata
     5101 aagaaacatt gagaaaatcc aagtacacca ttttttgcaa atgttttaag gtaaagaata
     5161 ccaactgcta tagtaccaat aaaagaacct atattaacaa aagaatattg tactgaaaat
     5221 gctgtatcaa gttcttcttg actatcaaaa agctgtccat ttaccgcaga tacgttacct
     5281 ttaaagaatg cagtaccaat tgaaactaag attatcattg catttaccat agaaactgta
     5341 gttgcaatag aaccaagata gtatcctacc cccatgataa gcatacctat aggtatagta
     5401 tatctagctc ctatccatct atctgatata taccccccaa ttataggtgc aaggtatgtg
     5461 aatgcaacaa ggttggcttg cattatagca gcttgtcctt tatctattcc aagaccacca
     5521 tgaactatag ctgttgtaag gaatatatat attaagtact ttgaagcata atatgctgct
     5581 ctttcaaatg agaaagttgt tgagcagata taaaatccca taggaaattt acccttcttt
     5641 tttactgttg agctcataat tttaaatcct ttcttaattg tatttttatt ttttacgttt
     5701 tgtccaaatt ctttctttta tgaaagatat aatattatta ttttgtaaaa caatttgtaa
     5761 ttattattaa gataattgcg catttatttg tagagtacat attctcatgg aataaaatta
     5821 atacacttct taatcataaa tttaaattat ataaattcac tattttcaga tatagttata
     5881 aattaatata ttctcatcta ataccatgaa aaaaccttcg ccatatgcaa ttcttatttt
     5941 ttacgtgata gtattttaca aactaaaatc ccccttttgt agcaacttat gtaattacat
     6001 tttagtgctt ttttaaagga gtctcgaata aagcaacata tattttgttc aaataatgtt
     6061 tttatttatt ttttaaattt atatattact tcacccaacc aattctcaac ttaaataact
     6121 aaactactat ctattcacag attaggctta tttcttacac attagtttat aataaacact
     6181 gtgaatctaa acataaaaac tgttatttta aagtaattac ccatatattc gctttgatac
     6241 tatttattga ggctatactc tttatgtata atatattatt tataaaatac ctcaaaatat
     6301 attattcata aaatacctca aactgaaaac tttttcacga atatttattt ttcacctccc
     6361 cttttttatt tcaccatgta aatcgtacca taaatatgca cttatatgca agaaaaaaat
     6421 ctattaatcg acagtaaata attagaaaaa ttcaaattat atttatcaat tatattatat
     6481 aaaatatttc ctatgaaaat ataaattaaa ttaatgttca gaatagtttt tagatatgaa
     6541 atcttgattt ttttattact ttacttattt gctcaaatat atttttgtat gcagtatata
     6601 ataatcaaat tatacacttc
//
LOCUS       DAYAOO010000150         6562 bp    DNA     linear   BCT 12-OCT-2024
DEFINITION  TPA_asm: Clostridioides difficile isolate ST8-SSI-h139-18
            SAMN40601845-rid21577343.denovo.154, whole genome shotgun sequence.
ACCESSION   DAYAOO010000150 DAYAOO010000000
VERSION     DAYAOO010000150.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN40601845
            Sequence Read Archive: SRR28438827
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 6562)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6562)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-MAY-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-MAY-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002157583.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002157583.1
            Genome Coverage       :: 163x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/11/2024 16:19:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 4,038
            CDSs (total)                      :: 3,963
            Genes (coding)                    :: 3,930
            CDSs (with protein)               :: 3,930
            Genes (RNA)                       :: 75
            rRNAs                             :: 6, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 60
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 33
            CDSs (without protein)            :: 33
            Pseudo Genes (ambiguous residues) :: 0 of 33
            Pseudo Genes (frameshifted)       :: 7 of 33
            Pseudo Genes (incomplete)         :: 25 of 33
            Pseudo Genes (internal stop)      :: 11 of 33
            Pseudo Genes (multiple problems)  :: 8 of 33
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6562
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN40601845-rid21577343.denovo.154"
                     /isolate="ST8-SSI-h139-18"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Denmark"
                     /collection_date="2018"
                     /collected_by="Statens Serum Institute"
     misc_binding    155..366
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            529..1818
                     /locus_tag="ACGI5H_003743"
     CDS             529..1818
                     /locus_tag="ACGI5H_003743"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896853.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytosine permease"
                     /protein_id="HFG9699416.1"
                     /translation="MEEEKINYALEQIPENQKRGWVAMFSVLVAIGVDLSSVILGAEL
                     AQSMPMKQAILSVIVGSFFSAILYTTCSLVGSSTSLSTSMITKYVFGEAGAKIFSLVI
                     GVSLLGWFGVQVGFFAQNAQIIIKDIFNLDVSMQILSLIGGLLMMSTAIYGYKAMEKL
                     SVYSVPFLLVLMMLTIFLAFRANGISVDDNMKSTMTFAGGVSLSMSIIIVGAIVSPDI
                     SRWAKSRRDCALSSFLGIQFGNAFMIIVSIVLVKCMGTSDIMRIFITLGIAIPGIIVL
                     TLAQWTTNTSNVYSASLSIALVLKKAPEKVLTIVLGIIATLLAVFGIYEGFIGFLNLL
                     GIVIAPVGGVYTAEYYIVKQELKGFDKGVLYKPIVKRSIVSWIIGILITYLSTYGFIT
                     LTTIAPLDGFIAGFVVQSIIGKVLCSTKNKQEIDKAV"
     gene            1872..2951
                     /locus_tag="ACGI5H_003744"
     CDS             1872..2951
                     /locus_tag="ACGI5H_003744"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420406.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF917 domain-containing protein"
                     /protein_id="HFG9699417.1"
                     /translation="MRFLTEESVDKIAVGAAVLGTGGGGDPYVGKLVAKQAIKKYGPV
                     KVISLDELDDDALVVPVSGMGSPVITIEKLLSEVELTTPLEIMEKLLNRKVDVIIPIE
                     IGGINSLMPIAVAAKKGLPILDADSMGRAFPEAQMVTFYLEGYEASPAVMSDEKGNSA
                     ILYPVDGIWSERLARTLTVEMGGSSSISDYNLSGAQVKKAAIGNTLTIAETIGGFLLE
                     NKSDSKGAVENILKELCGYKLFEGKVIDIKRELKGGFTRGHAFFAGINEYDGEYSILF
                     QNENLIAKKGDTPLCITPDLIAVLDLETGFPITTERIKYGSRVMVVAFPCNEKWRTEK
                     GIETVGPGYFGYDVEYKTVEELQGK"
     gene            2972..4516
                     /locus_tag="ACGI5H_003745"
     CDS             2972..4516
                     /locus_tag="ACGI5H_003745"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423610.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydantoinase/oxoprolinase N-terminal
                     domain-containing protein"
                     /protein_id="HFG9699418.1"
                     /translation="MYRVGIDVGGTNTDACILDGELKVIHSVKVATTKDVETGVYNAL
                     KKVIDESKIDHSLIKYAMLGTTHCTNAIVERKRLNNVAMIRIGKPATTAILPFIDWPE
                     DLREKIELDSILVSGGYEFDGRKINELCKDEVVEFCNRIKGKVESVAISGVFAPVNKQ
                     QEEEVAKWVREILGDIPISLSNEIGNIGILERENGAILNSALSQVGKAVSLGFEKALK
                     DLGIDAQIYFSQNDGTLMNLEYTMKYPIFTIGCGITNSIRGASFLSKVKNAIVLDVGG
                     TTSDLGVLYNGFPRESSIPVTIGGVHTNFRMPDVLTIGLAGGTCVKGEKDNIKIGPES
                     VGYRITEDAIIFGGDTLTLSDVVTKLDMAFEDRKSNVENLDKEYCNEVYKKVILKLED
                     AVDQMKTSQDDVELVLTGGGSIIVPEKLKGISNVIRPPHYTAANAIGAALGQISGDVE
                     KVYSLDKMSREDAIEDAKKEAVNKALKAGAKEDTIEVLNIEDVPLAYLPGNALLIKVK
                     VVGDLI"
     gene            complement(4679..5221)
                     /locus_tag="ACGI5H_003746"
     CDS             complement(4679..5221)
                     /locus_tag="ACGI5H_003746"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889655.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1697 domain-containing protein"
                     /protein_id="HFG9699419.1"
                     /translation="MKSYIALLRGINISGKNKIIMSELKASFVELGYSEVSTYLNSGN
                     VVFLSDVDDSKVISNTIRLMIKKQFELEIPVFIISQEELKDILNNAPNWWGDNNKEIY
                     DNLIFMFPDLSYDEFYDEVGNPKEEYEKVYHYKNAIFWSFSRKDYKKTNWWSKTASSN
                     VSDKITIRTANTVRKIVGMR"
     gene            complement(5369..5653)
                     /locus_tag="ACGI5H_003747"
     CDS             complement(5369..5653)
                     /locus_tag="ACGI5H_003747"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905562.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="HFG9699420.1"
                     /translation="MAKNTKQTTVHIDETLLKEVKRIGINENKSISQIINESIIDYIL
                     VYRENEDKEKNEHDKNLNETINEFKKEEEKRMQAKSAARAIAEAKKRVLY"
     gene            complement(5716..6480)
                     /locus_tag="ACGI5H_003748"
     CDS             complement(5716..6480)
                     /locus_tag="ACGI5H_003748"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420423.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lysophospholipid acyltransferase family protein"
                     /protein_id="HFG9699421.1"
                     /translation="MNNYLKFATYQLIGFTSSIPRLIKIKKNPDKFSLKEKFEFMQKQ
                     AKKSLDIVNIELNIIGKETLPKEPLLFVVNHSSMLDSFILTASVERPIGCVIADEPVW
                     RNIPIFKEWAKLLRCVYVNRKNNREGIKSIAQASQNILTGQSMAVFPEGDLTWIKEPN
                     SLVSEFRSGALKIAYKAKCPIVPLVIKNSKDTYEGYQPIGKINSVPVEVEFLEPIYDH
                     IENPRLKSSVLGENIKNKMINTIENFRKSNKTFKEF"
BASE COUNT         2294 a          809 c         1131 g         2328 t
ORIGIN      
        1 ttgatgaaat ttaaaaaaat acattatata aatatagtaa tagtatgaaa atttacatat
       61 aaaactaaaa aatgcaagta attgactttt taagttgaca aaatattgca tatatattat
      121 gatataaatc ataaattaac tacaaatcaa tattatatat tcgtagaaga agaaagtagc
      181 ataaaggaat tttacagaga gttagatttg gctgagaact aatattggaa tttatgtgaa
      241 aaggactttg gagaatacta ttgtaattat gttagaatag tggtttaatt cgccttaaga
      301 aaatgagtga gtaaaattaa tttttactaa taagagtggt aacacggatt tatattcgtc
      361 tcttggattt ttccaagagg cgttttttat tataaactta tttcagaaaa tttaaaacta
      421 tatattaaat gaaaattata aaaatatgat agttaataaa tttataaatt agaaaattgt
      481 aaaatatgct aaggtcagta gttttacgat ttaaatggag ggatgaaaat ggaagaagaa
      541 aaaattaact atgctctgga acagattcca gagaatcaaa aacgtggttg ggtagctatg
      601 ttttcagttt tagtagcaat aggtgtggat ttatcatctg ttattttagg cgctgagttg
      661 gcacagagta tgccaatgaa acaagcaata ttgtcagtaa ttgttggttc atttttttct
      721 gcaattttgt atactacatg ctctttggtt ggttcatcta caagtttatc tacatctatg
      781 ataacaaagt atgtatttgg agaagctgga gcaaaaatat tttctctagt tataggggtt
      841 tctctattag gttggtttgg agttcaagta ggtttctttg ctcaaaatgc acagataata
      901 ataaaagata tatttaattt agatgtcagt atgcagattt taagcctaat aggtggtctc
      961 ttgatgatga gtactgcaat ttatggatat aaggcaatgg agaagttgag tgtgtattca
     1021 gtaccatttt tattagttct tatgatgcta actatattct tagcttttag agcaaatgga
     1081 atttcagttg atgataatat gaaatctact atgacatttg caggtggagt ttctctgtca
     1141 atgagtataa taatagttgg tgcaattgta tctcctgata taagtcgttg ggctaaaagt
     1201 agaagagact gtgctctttc aagctttttg ggaatacaat ttggaaatgc ttttatgata
     1261 atagtttcga tagtattagt aaaatgtatg ggaacttcag atattatgag aatttttatt
     1321 acattaggaa ttgctatacc aggtataata gtacttacat tagcacaatg gactacaaat
     1381 acaagtaatg tatattcagc atcattaagt atagctcttg tacttaagaa ggctcctgag
     1441 aaagtattaa ctatagtcct tggtattata gcaacattat tggctgtatt tggaatatat
     1501 gaaggtttta taggattttt aaatttactt ggaattgtaa ttgcacctgt tggtggtgta
     1561 tatacagcag aatattacat agtaaagcaa gaacttaaag gctttgataa aggagtatta
     1621 tataaaccaa tagttaaacg ttcaatagtg tcttggataa ttggtatatt aataacttac
     1681 ctttcaacat atggatttat aactcttact actatagcac ctttagatgg ttttatagca
     1741 gggtttgtag tacaatctat tattggaaaa gtgctttgtt caacaaaaaa taagcaagaa
     1801 atagacaaag cagtataaag aaatttgttt ataaagtata aaataaatta gaaatatgag
     1861 gagaaagtaa catgagattt ttaacagaag aaagtgtaga taaaatagca gttggtgcag
     1921 cagtgcttgg aactggaggt ggaggtgacc catatgtagg taaattggtt gcaaaacaag
     1981 ccattaaaaa gtatggtcct gtaaaagtaa taagtttaga tgaacttgat gatgatgctt
     2041 tggtagttcc agtatctggt atgggttctc ctgtaattac aatagaaaaa ttactttcag
     2101 aagtagagtt aactacccct ttagaaataa tggagaaatt attaaataga aaagtggatg
     2161 ttataattcc tatagaaata ggagggataa actcacttat gcctatagca gttgctgcta
     2221 aaaaaggact tcctatctta gatgcagatt ctatgggtag agctttccct gaagctcaaa
     2281 tggtaacttt ttatcttgaa ggatatgagg catctcctgc cgtaatgtct gatgaaaaag
     2341 gtaattctgc catcctttat cctgtggatg gaatttggtc agaaagatta gctagaactt
     2401 taactgtaga aatgggagga agttcttcta ttagtgacta taatttaagt ggagctcaag
     2461 ttaaaaaagc tgctataggt aatactctta caatagctga aactatagga gggtttttac
     2521 ttgaaaataa atctgattca aaaggtgctg ttgagaatat actaaaagaa ttgtgtggat
     2581 acaagttatt tgaaggaaaa gtaattgata ttaagagaga gttgaaaggt ggatttacta
     2641 gaggacatgc cttttttgct gggattaatg agtatgatgg agagtattct atattattcc
     2701 aaaatgagaa tttaattgcc aaaaaaggtg atacaccact ttgtattaca ccagatttaa
     2761 tagcagtatt agatttagaa actggatttc caataactac agagagaata aaatatggct
     2821 ctcgtgttat ggtagtagct tttccttgta atgaaaaatg gagaacagaa aaaggaattg
     2881 agacagttgg acctggatac tttggatatg atgtggaata taaaacagta gaagaattac
     2941 aaggaaaata aaagtttagg aggaaatttt gatgtatcgt gtaggaattg acgttggagg
     3001 aacaaataca gatgcttgta tactggatgg ggaattaaaa gtaattcatt cagttaaggt
     3061 ggcaactaca aaagatgttg aaactggtgt ttacaatgcc ttaaaaaaag ttatagatga
     3121 aagtaagatt gaccattcat taataaaata tgctatgctt ggtacaactc attgtacaaa
     3181 tgctattgta gaaagaaaaa gacttaataa tgtggctatg ataagaatag gaaagccggc
     3241 cactactgcc attcttccat ttatagattg gccagaagac ttaagagaaa aaatagaatt
     3301 agattcaata ttggtatctg gtggatatga gtttgatggc agaaaaataa atgaactttg
     3361 taaagatgaa gttgtagagt tttgcaatag aataaaaggc aaagtggaaa gtgttgcaat
     3421 aagtggagta tttgctccag taaataaaca acaagaagaa gaagttgcaa aatgggttag
     3481 agaaatttta ggggatattc ctatatcttt atcaaatgaa ataggtaata taggtatatt
     3541 agaaagagaa aatggagcta ttttaaattc tgcattgtct caagtaggta aagctgtatc
     3601 tttaggattt gaaaaagcac ttaaagattt aggtatagat gctcaaatat atttcagtca
     3661 aaatgatgga acattaatga atttagagta tacaatgaaa tacccaattt ttacaattgg
     3721 atgtggaata acaaattcta taagaggagc ttccttctta tcaaaagtaa aaaatgcaat
     3781 agtattagat gttggtggaa ctacaagcga cttgggtgta ctatataatg gattccctag
     3841 agaatcatct attccagtta caattggagg agtacataca aactttagaa tgccagatgt
     3901 tttaactatt ggtcttgctg gtggtacatg tgtaaaaggc gaaaaagata atataaagat
     3961 aggtcctgaa agtgtgggat atagaataac tgaagatgca ataatatttg gtggagacac
     4021 tctaacttta tcagatgttg ttacaaaatt agatatggcg tttgaagata gaaaaagcaa
     4081 tgttgaaaac ttagataaag agtattgtaa tgaggtatat aagaaggtta ttttaaaatt
     4141 agaagatgct gtagaccaaa tgaagactag tcaagatgat gttgaattgg ttttaactgg
     4201 tggaggaagt ataattgttc ctgaaaaact aaaaggcata agcaatgtta taagacctcc
     4261 tcattatact gctgcaaatg ctattggtgc agctttagga caaataagtg gagatgtaga
     4321 aaaagtatac agtttagata aaatgtcgag agaagatgcc atagaagatg caaaaaaaga
     4381 ggctgtaaat aaagctctaa aagctggtgc taaagaagat actatagaag tattaaatat
     4441 agaagatgtt ccacttgcat accttcctgg taatgcactt cttataaaag taaaagttgt
     4501 tggtgattta atttaaagaa taaatataag tatttccaga attatataaa tatttctgga
     4561 ctcattttta aacttatttt atcaataaaa acagcataac ttttgactat attcttataa
     4621 gtttccgaac agccgatata tacctatttt ttgaggttta tcggctgttt gttatctttt
     4681 atcgcattcc aactattttt cttaccgtat ttgctgtacg aattgtaatc ttatcactta
     4741 catttgaact ggcagtcttt gaccaccaat ttgtcttttt ataatcttta cgactaaaag
     4801 accaaaagat agcattttta taatgatata ctttttcata ctcttcttta ggatttccaa
     4861 cctcatcata aaactcgtca taagataagt caggaaacat aaaaataaga ttatcatata
     4921 tttctttgtt gttatctccc caccaattag gagcattatt tagtatatct tttaactctt
     4981 cttgtgaaat aataaaaact ggtatttcca attcaaactg tttttttatc attaatctta
     5041 ttgtatttga gataaccttg ctgtcatcta catcacttaa aaagacaaca ttaccactat
     5101 taaggtatgt agaaacttct gaataaccaa gttctacaaa gcttgctttt aattcagaca
     5161 taattatctt gttcttacca cttatattga tacctcttaa taatgcgata taacttttca
     5221 tataataatt tcacctctaa acattcacat ttttctatgt agtacaaact tgaatttgca
     5281 tcttttataa ttctttcaaa acttcttcat atgtaatttt tttaatataa aaaaatcggt
     5341 gcttaatttg taccgatttt tgtttttcct agtaaagaac tcgttttttt gcttctgcta
     5401 tagctctagc agcacttttt gcttgcattc ttttttcttc ttctttttta aattcattta
     5461 ttgtttcatt tagattctta tcatgttcat ttttttcttt atcttcgttt tctctgtata
     5521 ctaatatata atctattatt gattcgttta ttatctgaga tatactttta ttttcattaa
     5581 ttcctattct cttaacttcc ttaagtagag tctcatcaat atgaaccgtt gtttgctttg
     5641 tattttttgc caccttaatc acctcttaaa aaaaattcta acattaaaat tttttttagt
     5701 caataaattt taatattaaa attctttaaa tgttttattt gattttctaa aattttctat
     5761 tgtatttatc atcttatttt ttatattttc acctagtaca gaagacttta gtctaggatt
     5821 ttcgatatgg tcataaattg gttctaaaaa ttcaacttcg acaggaacag agttaatttt
     5881 accaataggt tggtatcctt cataagtatc ttttgaattt tttattacga gtggaacaat
     5941 agggcatttt gctttatatg ctatctttaa agctccactt ctaaactccg aaaccaatga
     6001 atttggttct ttaatccatg ttaaatctcc ttctggaaac actgccatac tttgacctgt
     6061 aagtatattt tgagaggctt gggctatact ctttataccc tcacgattgt tttttctgtt
     6121 tacatataca catcttagta attttgccca ttctttaaat ataggtatat ttctccaaac
     6181 tggttcatct gcaattacac atccaattgg tctttctaca cttgctgtta gtatgaagct
     6241 gtcaagcata ctagaatgat ttacaacaaa tagaagtggt tcttttggca gtgtttcctt
     6301 accaattata ttaagctcta tattcactat atctaaagat tttttagctt gtttttgcat
     6361 aaattcaaat ttttccttta agctaaattt atcaggattc tttttaattt taataagcct
     6421 aggtatagaa gatgtaaaac ctataagttg atatgtagca aattttaagt aattattcat
     6481 aaaattatct ccttaaaata aaattattta ttactgtaaa gattttaaca taaaataaaa
     6541 tttaagtcta ttttaattca at
//
LOCUS       DAYAOO010000151         6430 bp    DNA     linear   BCT 12-OCT-2024
DEFINITION  TPA_asm: Clostridioides difficile isolate ST8-SSI-h139-18
            SAMN40601845-rid21577343.denovo.155, whole genome shotgun sequence.
ACCESSION   DAYAOO010000151 DAYAOO010000000
VERSION     DAYAOO010000151.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN40601845
            Sequence Read Archive: SRR28438827
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 6430)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6430)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-MAY-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-MAY-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002157583.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002157583.1
            Genome Coverage       :: 163x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/11/2024 16:19:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 4,038
            CDSs (total)                      :: 3,963
            Genes (coding)                    :: 3,930
            CDSs (with protein)               :: 3,930
            Genes (RNA)                       :: 75
            rRNAs                             :: 6, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 60
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 33
            CDSs (without protein)            :: 33
            Pseudo Genes (ambiguous residues) :: 0 of 33
            Pseudo Genes (frameshifted)       :: 7 of 33
            Pseudo Genes (incomplete)         :: 25 of 33
            Pseudo Genes (internal stop)      :: 11 of 33
            Pseudo Genes (multiple problems)  :: 8 of 33
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6430
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN40601845-rid21577343.denovo.155"
                     /isolate="ST8-SSI-h139-18"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Denmark"
                     /collection_date="2018"
                     /collected_by="Statens Serum Institute"
     gene            290..1234
                     /locus_tag="ACGI5H_003749"
     CDS             290..1234
                     /locus_tag="ACGI5H_003749"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902566.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP phosphoribosyltransferase regulatory
                     subunit"
                     /protein_id="HFG9699422.1"
                     /translation="MKFLRIEDEVIYSKKRYKLKREIDKLFLDEEYFQIEPQLFEEYD
                     EFTTINNKIPEESMVKVVNGKVMVLRADITTSIIKSLVPRWEDGLKLKLFYNSSIYKN
                     KNTVGIKEIRQIGCEYLGEASVEADREVVKLALKILEKYNNNFILEVGSSKYIHGLLE
                     ELNLNKNCENQIKNLLYTKNTHELKVYIEELKIKREVKELLSNILSLQGNLYNVIEKS
                     NKFYCNNKMKQALEELKQVNNLIEECNFLDKARFDLSMITMLDYYEGIMFRGYYPNSY
                     KEILSGGRYDSLTKEYGKEIPAIGFTLSVDELMKYVYK"
     gene            1256..1882
                     /gene="hisG"
                     /locus_tag="ACGI5H_003750"
     CDS             1256..1882
                     /gene="hisG"
                     /locus_tag="ACGI5H_003750"
                     /EC_number="2.4.2.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902568.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0003879 - ATP phosphoribosyltransferase
                     activity [Evidence IEA];
                     GO_process: GO:0000105 - L-histidine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP phosphoribosyltransferase"
                     /protein_id="HFG9699423.1"
                     /translation="MDYLTIALAKGRIEGESFKKFKKMGLGDSIDTDTRKLIFKDEEN
                     KIIYIHVKPSDVVTYVEKGVADLGIAGKDTILENETDVYEIYDLGFGKCKFAVAGLKG
                     DSIYREDEYLKVATKYPNIAKKYFKEKGQKIEIIKLNGSVELAPIVGLSDVIVDIVET
                     GNTLKANGLEILEDICNISARIISNRASYRFKYEQIQNIIRLFEELDN"
     gene            1916..2965
                     /gene="hisC"
                     /locus_tag="ACGI5H_003751"
     CDS             1916..2965
                     /gene="hisC"
                     /locus_tag="ACGI5H_003751"
                     /EC_number="2.6.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004400 - histidinol-phosphate
                     transaminase activity [Evidence IEA];
                     GO_process: GO:0000105 - L-histidine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="histidinol-phosphate transaminase"
                     /protein_id="HFG9699424.1"
                     /translation="MREKESIRELRGYEPNHVNCKVKLDANEGSKRLFKYLIKEISDS
                     DIDLNLYPEDSYSDLKESIIDYINISGVNKKNLLVGNGSSEIIDLIIHTFVDKDEVIL
                     SFSPSFSMYSIYSQINGSKFIGVESDENLVINIDNVIEKVKENNPKIVIVCNPNNPTG
                     TILKREEIIKLLDSTNSLVVLDEAYMDFGEESMLSDVFKYDNLIVLRTLSKAFGLAGI
                     RTGYMLSNSSLINSVEKVRPPYNLNSLSDFIATRALRNKDVVKAYIKEVKEEREVLYE
                     EMIGMGIKAYKSQANFILFYSEIENLSQKLIDRGVLIRKFGGKLENYYRVTIGDKEEN
                     SMFVGAIRDILKKEK"
     gene            2968..3546
                     /gene="hisB"
                     /locus_tag="ACGI5H_003752"
     CDS             2968..3546
                     /gene="hisB"
                     /locus_tag="ACGI5H_003752"
                     /EC_number="4.2.1.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902569.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004424 - imidazoleglycerol-phosphate
                     dehydratase activity [Evidence IEA];
                     GO_process: GO:0000105 - L-histidine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="imidazoleglycerol-phosphate dehydratase HisB"
                     /protein_id="HFG9699425.1"
                     /translation="MRIWKVERNTLETQILVELNIDGSGKAEIDTGIGFLDHMLTLMS
                     FHGKFDLKVICKGDTYVDDHHSVEDIGIAIGEAFKNALGDKKGIRRYSNIYIPMDESL
                     SMVAIDISNRPYLVFNAKFDTQMIGSMSTQCFKEFFRAFVNESRVTLHINLLYGENDH
                     HKIESIFKAFARALKEGSEIVSNEIASSKGVL"
     gene            3548..4153
                     /gene="hisH"
                     /locus_tag="ACGI5H_003753"
     CDS             3548..4153
                     /gene="hisH"
                     /locus_tag="ACGI5H_003753"
                     /EC_number="4.3.2.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436678.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000107 - imidazoleglycerol-phosphate
                     synthase activity [Evidence IEA];
                     GO_process: GO:0000105 - L-histidine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="imidazole glycerol phosphate synthase subunit
                     HisH"
                     /protein_id="HFG9699426.1"
                     /translation="MNIIVDYGLGNIDSVSRGFRKAGIETKISSDIDEIKQADSLILP
                     GVGAFRDSISALDKLGLIPIIKEHVSKGKFMIGICLGMQLLYEKSYEYGEYEGLGLIK
                     GSIDKLDISLKVPHMGWNNLKFNKANDDILKYINEDDYVYFVHSYYANSSNEELIAFS
                     EYEKKIPAIVRKGNVYGIQFHPEKSGEVGLNILRAYGEMIK"
     gene            4150..4872
                     /gene="hisA"
                     /locus_tag="ACGI5H_003754"
     CDS             4150..4872
                     /gene="hisA"
                     /locus_tag="ACGI5H_003754"
                     /EC_number="5.3.1.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896508.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003949 -
                     1-(5-phosphoribosyl)-5-[(5-
                     phosphoribosylamino)methylideneamino]imidazole-4-
                     carboxamide isomerase activity [Evidence IEA];
                     GO_process: GO:0000105 - L-histidine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="1-(5-phosphoribosyl)-5-[(5-
                     phosphoribosylamino)methylideneamino]imidazole-4-
                     carboxamide isomerase"
                     /protein_id="HFG9699427.1"
                     /translation="MIIFPAIDIKDNKCVRLTQGEFDKVNVYYDNPLEVAYKWKNEGA
                     EYIHIVDLNGARSEFGVNTKIIEDIANNIDIPIQVGGGVRDKEKVKSLINAGVTRVIL
                     GSIAIENLNLVEELVNEYKEKIVVSIDAKDGKVAVRGWEVVSNVDSLTLCKQLEKIGV
                     QTIVYTDISKDGMLQGPNFDIYERIAKETSLNVIASGGVTSIEDVKRLKAMNLYGAII
                     GKALYDKKIDFKEAQQLCLLGE"
     gene            4854..5612
                     /gene="hisF"
                     /locus_tag="ACGI5H_003755"
     CDS             4854..5612
                     /gene="hisF"
                     /locus_tag="ACGI5H_003755"
                     /EC_number="4.3.2.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420105.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000107 - imidazoleglycerol-phosphate
                     synthase activity [Evidence IEA];
                     GO_process: GO:0000105 - L-histidine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="imidazole glycerol phosphate synthase subunit
                     HisF"
                     /protein_id="HFG9699428.1"
                     /translation="MLTRRIIPCLDVRNGRVVKGKKFKDIVDVDSPEVLGKFYSDCGA
                     DELVFYDITASNEERKTSLEFVTKVAENINIPFCVGGGVNKLEDFTDILRKGADKVSI
                     NSSAVKNPELIREASLKFGAQCVVLSIDAKKNEEGSWSVYVKGGREKTNLDAIEWAVK
                     GVELGAGEIVVNSMDEDGMKNGYDIELLSKITSLVNVPVIASGGAGKKEDFYEAVNKS
                     NVDGILAASVFHFGEIKINDLKKYLKDMGVEVRL"
     gene            5640..6308
                     /gene="hisIE"
                     /locus_tag="ACGI5H_003756"
     CDS             5640..6308
                     /gene="hisIE"
                     /locus_tag="ACGI5H_003756"
                     /EC_number="3.5.4.19"
                     /EC_number="3.6.1.31"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436669.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004635 - phosphoribosyl-AMP
                     cyclohydrolase activity [Evidence IEA];
                     GO_function: GO:0004636 - phosphoribosyl-ATP diphosphatase
                     activity [Evidence IEA];
                     GO_process: GO:0000105 - L-histidine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional phosphoribosyl-AMP
                     cyclohydrolase/phosphoribosyl-ATP diphosphatase HisIE"
                     /protein_id="HFG9699429.1"
                     /translation="MDNKCNNVYSDEVEKFIRSIKFDDKGLVPVVVQEVVSKDVLMLA
                     YMNKDVIKKTLKDKVACYFSRSRQELWVKGETSGNTQKVVKMSYDCDVDTILLFVEQT
                     GVACHTGNYSCFYRDLFDDSSKMELEVQTNILKELYDLINERKNNPVEGSYTNYLFEK
                     GIDKILKKVGEESSEVIIASKNTDKSELIYEISDLVYHTLVLMIEKGVEIDEIKKELL
                     KRRK"
BASE COUNT         2629 a          539 c         1262 g         2000 t
ORIGIN      
        1 aatttagaat attaataaaa attatttggg aggaaattat catggtgaga ttaaatatag
       61 taaaattaaa tacaaaatta aatcatcacc atcatcatag attaaaggga ttgtaatatg
      121 aaattaattc atagacacaa gccctgtttt tagtgtaatt ggtcttgtat ctatgatggg
      181 aagtaatttt aagagaaaat tatagccata taggtataaa gcctatgtgg cttttttatt
      241 gttttaaatt tgcaaatata agagtaaatt taatgaagag ggtgagaatg tgaaattttt
      301 gaggattgaa gatgaggtta tttattctaa aaaaagatat aaattaaaaa gggaaataga
      361 taaacttttt ttggatgaag aatattttca aatagaacca caattatttg aagaatatga
      421 tgaatttaca actataaata ataaaattcc agaagaatct atggtaaagg ttgtaaatgg
      481 aaaagtaatg gtacttagag ctgatataac tacaagtata ataaaaagcc ttgtaccaag
      541 atgggaagat ggtttaaagc ttaagctttt ttataattca tcaatatata aaaataaaaa
      601 tacagttgga ataaaagaga taagacaaat aggttgtgag tatctaggag aagcctctgt
      661 agaagcagat agagaagtag tgaaattagc tcttaagata cttgaaaaat acaataataa
      721 ttttattcta gaggttggga gtagcaagta tattcatggt ttgttagaag aattaaattt
      781 aaataagaat tgtgaaaatc aaattaaaaa tttactatat acgaagaaca ctcatgaact
      841 aaaagtatat attgaagaat taaaaattaa gcgtgaagta aaagagttat tatcaaatat
      901 tttaagttta caagggaatt tatataatgt tattgaaaaa tcaaacaagt tctattgtaa
      961 taataagatg aagcaagctc ttgaagaatt aaagcaagta aataatttaa ttgaggaatg
     1021 taatttttta gataaggcta gatttgattt atcaatgatt actatgcttg actattatga
     1081 aggaattatg tttagaggat actacccaaa ctcatataaa gaaattctta gtggcggaag
     1141 atatgattct ttaactaaag agtatggaaa agaaattcca gccattggat ttacactaag
     1201 tgttgatgag ttaatgaagt atgtatataa gtaaagttta gaaggaggga ttgctttgga
     1261 ttatttgact atagcactag caaaaggacg aattgaaggg gaatcattta aaaaatttaa
     1321 aaaaatgggt ctaggagaca gtatagacac agatacgaga aaactaattt ttaaagatga
     1381 agaaaataaa attatatata tacatgtaaa gccatcagat gtagttacat atgttgaaaa
     1441 aggagtcgct gacctcggta tagcaggtaa agatactatt ttagaaaatg agacagatgt
     1501 atatgaaata tatgatttag gttttggaaa atgtaaattt gctgtagcag gattaaaggg
     1561 agatagcata tatagagaag atgaatattt aaaagtggca acaaagtatc ccaatatagc
     1621 aaaaaagtat tttaaagaga aaggtcaaaa aattgaaata ataaaattaa atggttctgt
     1681 agaactagct ccaatagtag ggttgtcaga tgtaattgta gatatagttg agactggcaa
     1741 tacacttaaa gcaaatggtc ttgaaatatt agaagacata tgtaatataa gtgctagaat
     1801 tatatcaaat agagctagct atagatttaa atatgaacaa attcagaata taattcgttt
     1861 atttgaagaa cttgataatt aaaatataat tgagctttat aaggagggat ttaagttgag
     1921 agaaaaagaa agcataagag agttaagggg atatgaacca aatcacgtaa actgtaaagt
     1981 aaaacttgat gcaaatgaag gaagtaagag gttgtttaaa taccttatta aagaaatttc
     2041 agatagtgat atagatttaa atttatatcc tgaagattct tatagtgatt tgaaagaatc
     2101 tataatagat tacataaata tttctggagt aaataagaaa aatcttctag taggaaacgg
     2161 ttcaagtgaa ataattgatt taataataca tacttttgta gataaagatg aagtaatatt
     2221 gagtttctct ccaagtttta gtatgtattc tatatatagt cagataaatg ggtctaaatt
     2281 tataggtgtt gaaagtgatg aaaatttagt tataaatata gataatgtga ttgaaaaagt
     2341 aaaggagaat aatcctaaaa tagtaattgt atgtaatcct aataatccaa ctggaacaat
     2401 attaaagagg gaagagataa taaagctttt agattcaact aatagtctag tggttttaga
     2461 tgaagcatat atggattttg gagaagaaag catgttaagt gatgttttta agtatgataa
     2521 tctaatagtt cttagaactt tatcaaaggc atttggattg gctggaataa gaacaggata
     2581 tatgttatct aatagtagtt taataaattc tgttgagaaa gtaagacctc catataattt
     2641 aaattcatta tcagacttta ttgctacaag agcacttaga aataaagatg tggtaaaggc
     2701 ttatataaag gaagtaaaag aggaaagaga agttttatat gaagaaatga ttggtatggg
     2761 aattaaagca tacaaatcac aagcaaattt tatattattt tattctgaaa tcgaaaattt
     2821 atcacaaaaa cttattgata gaggtgtttt aataagaaaa tttggtggaa agttagaaaa
     2881 ttattacaga gttacaattg gtgataaaga agaaaattct atgtttgttg gagctataag
     2941 agatattttg aaaaaggaga aataggtatg agaatttgga aggtagaaag aaatactctt
     3001 gaaacacaga ttttagtaga attaaatatt gatggttctg gtaaagctga aatagatact
     3061 ggaataggat ttttagacca tatgcttacc ttaatgtcat ttcatggcaa gttcgattta
     3121 aaagtgattt gtaagggtga tacatatgta gatgaccacc atagtgtaga agatataggt
     3181 atagctatag gtgaagcatt taaaaatgca ctaggtgaca aaaaaggaat acgaagatat
     3241 tctaatatct atatacctat ggatgaatct ctatcaatgg tagcaataga tataagcaat
     3301 agaccttatc ttgtatttaa tgctaaattt gatacccaaa tgattggtag tatgagtact
     3361 caatgcttta aagaattttt tagagctttt gtaaatgaat cgagagtaac attacatatc
     3421 aatctcttat atggggaaaa tgaccatcat aagatagaaa gtatttttaa agcatttgca
     3481 agagctttaa aagagggtag tgaaatagtt tctaatgaga tagcatcttc aaagggggtt
     3541 ttgtagaatg aatataatag tagactatgg tcttggaaat atagattctg tgtctagggg
     3601 ttttagaaaa gctggaatag aaactaaaat ttctagtgat atagatgaaa taaaacaggc
     3661 agattcactt atacttccag gtgttggagc ttttagagat tctataagtg ccttagataa
     3721 actaggattg ataccaataa taaaggagca tgtttctaag ggtaaattta tgataggtat
     3781 atgtctagga atgcaattac tttatgaaaa aagttatgag tatggagaat atgaaggatt
     3841 aggacttata aaaggaagta ttgataaact ggatataagt ttaaaagtgc cacatatggg
     3901 atggaataat ctaaaattta ataaggcaaa tgatgatata cttaaatata taaatgaaga
     3961 tgattatgta tacttcgttc actcatatta tgcaaattca tcaaatgaag aactaattgc
     4021 attttcagaa tatgaaaaga aaatccctgc tattgttaga aaaggcaatg tatatggtat
     4081 acaatttcat cctgaaaaaa gtggagaagt agggttaaat atattaagag catatgggga
     4141 gatgataaaa tgataatatt tccagcaata gatataaaag ataataagtg tgtaagactc
     4201 acacaaggag aatttgacaa agtaaatgta tattatgata atccattaga agtagcatat
     4261 aaatggaaaa atgaaggagc agaatatata catatagtag atttaaatgg tgctagaagt
     4321 gaatttggtg taaatacaaa aataattgag gacatagcaa acaatataga tatacctatt
     4381 caagttggcg gtggagttag ggataaggaa aaagtcaaaa gtttaataaa tgctggtgtt
     4441 actagagtaa tattaggtag tatagcgatt gaaaatttga atttagttga agaattggtc
     4501 aatgaatata aagagaaaat tgtagtttct atagatgcta aagatggaaa agtagcagtt
     4561 aggggatggg aagttgtaag caatgtagac tcattaacat tatgtaaaca acttgaaaag
     4621 ataggtgtac aaactattgt ttatacagat atatcaaaag atgggatgtt gcaaggtcca
     4681 aattttgaca tatatgaaag aatagcaaag gaaacatcac taaatgttat tgcttctgga
     4741 ggcgtaactt ctatagaaga cgtaaaaaga ctaaaagcta tgaacttata tggtgcaata
     4801 ataggtaaag cgctttatga taaaaagata gactttaagg aggcacaaca attatgctta
     4861 ctaggagaat aataccttgt ctagatgtga gaaatggaag agttgtaaag gggaaaaaat
     4921 ttaaagatat agtagatgtt gatagtccag aagtacttgg aaaattttat agtgattgtg
     4981 gtgcagatga acttgtattc tatgatataa ctgcatcaaa tgaagagaga aagacatctt
     5041 tagaatttgt gacaaaagtt gcagaaaata taaatatacc attttgtgtt ggtggaggag
     5101 taaataaatt agaagatttc actgatattt taagaaaagg tgctgataaa gtttctataa
     5161 attcatcagc agtcaaaaat cctgaattaa taagggaagc ttcattaaaa tttggagcac
     5221 aatgtgttgt tttatcgata gatgcaaaga aaaatgaaga gggttcatgg agcgtatacg
     5281 taaaaggtgg aagagaaaaa actaatctgg atgcaattga atgggctgtt aaaggtgtag
     5341 aacttggagc aggagaaatc gttgtaaata gtatggatga agatggaatg aaaaatggat
     5401 atgatataga attattatca aagataactt ctttagtaaa tgtacctgtt atagcatctg
     5461 gaggcgctgg aaaaaaggaa gatttttatg aggcggttaa taaatccaat gtagatggaa
     5521 ttttagcagc atctgttttt cattttggcg agataaaaat aaacgattta aagaaatatt
     5581 taaaagacat gggtgtagaa gtaagattat aagttaaata ctaaaaggag attagaaata
     5641 tggataataa gtgtaacaat gtatacagtg atgaagtaga gaaatttata agaagtataa
     5701 agtttgatga taaagggtta gtccctgttg ttgttcaaga ggtagttagc aaagatgtac
     5761 tgatgttagc atatatgaat aaagatgtga taaagaaaac cttaaaagat aaagtagctt
     5821 gctattttag tagaagtaga caagaacttt gggttaaagg tgagacatct ggtaatactc
     5881 aaaaagtagt taagatgtct tatgattgtg atgtagatac tatactactt tttgttgaac
     5941 aaactggtgt agcttgtcat acaggcaatt attcttgttt ttacagagac ttgtttgatg
     6001 atagttcaaa aatggagctt gaagtacaaa caaatatatt gaaagaatta tatgatttaa
     6061 tcaatgaaag aaaaaataat ccagttgaag gttcttatac taattatctt tttgaaaaag
     6121 gaatagataa gattcttaaa aaagtaggtg aagagagtag tgaggtaatt atagcatcaa
     6181 aaaatactga taaaagtgaa cttatttacg aaattagcga tttagtatat catacattgg
     6241 ttttaatgat agaaaaaggt gttgaaattg atgaaataaa aaaagaatta cttaaaagaa
     6301 gaaaatagaa taagatagat taatgggtaa taagaaaata taccactttt aataaaaagt
     6361 ggtatatttt ttattttata ttttgattta tagaataata tttaaattac ttgataaaat
     6421 taactatata
//
LOCUS       DAYAOO010000152         6420 bp    DNA     linear   BCT 12-OCT-2024
DEFINITION  TPA_asm: Clostridioides difficile isolate ST8-SSI-h139-18
            SAMN40601845-rid21577343.denovo.156, whole genome shotgun sequence.
ACCESSION   DAYAOO010000152 DAYAOO010000000
VERSION     DAYAOO010000152.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN40601845
            Sequence Read Archive: SRR28438827
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 6420)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6420)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-MAY-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-MAY-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002157583.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002157583.1
            Genome Coverage       :: 163x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/11/2024 16:19:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 4,038
            CDSs (total)                      :: 3,963
            Genes (coding)                    :: 3,930
            CDSs (with protein)               :: 3,930
            Genes (RNA)                       :: 75
            rRNAs                             :: 6, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 60
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 33
            CDSs (without protein)            :: 33
            Pseudo Genes (ambiguous residues) :: 0 of 33
            Pseudo Genes (frameshifted)       :: 7 of 33
            Pseudo Genes (incomplete)         :: 25 of 33
            Pseudo Genes (internal stop)      :: 11 of 33
            Pseudo Genes (multiple problems)  :: 8 of 33
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6420
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN40601845-rid21577343.denovo.156"
                     /isolate="ST8-SSI-h139-18"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Denmark"
                     /collection_date="2018"
                     /collected_by="Statens Serum Institute"
     gene            <1..410
                     /locus_tag="ACGI5H_003757"
     CDS             <1..410
                     /locus_tag="ACGI5H_003757"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861712.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="DUF4004 family protein"
                     /protein_id="HFG9699430.1"
                     /translation="IANMFMKKDINKEFDIDFILSKEVICNYTKEIFQNLYKKEQSIG
                     KKELLILSIIEKFLVKSIITFEELKLIVNIIEENFTSIYNESGKIYLFRKFGVPFVVG
                     CLDYKKVKFEKDVVKIIEVDLTKEINDISIKLS"
     gene            complement(710..1297)
                     /gene="rbr"
                     /locus_tag="ACGI5H_003758"
     CDS             complement(710..1297)
                     /gene="rbr"
                     /locus_tag="ACGI5H_003758"
                     /EC_number="1.11.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426696.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0009055 - electron transfer activity
                     [Evidence IEA];
                     GO_function: GO:0016692 - NADH peroxidase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="rubrerythrin"
                     /protein_id="HFG9699431.1"
                     /translation="MNLKDSKTKENLLRAFAGESQARNRYNISASVAKKEGLYIIESL
                     FNYTADQEKSHAKQFFSKLKEFAGENISISGAYPVDLYDKTAQHLKAAQHNELQEWDD
                     VYKNFGKTAREEGFESIAKLFENIAEIEKVHGDRFGRYATDLEEGTLFRRNEDIQWIC
                     THCGHIHIGKEAPKACPVCLHPQGYFLDFKNSLFE"
     gene            complement(1383..1820)
                     /locus_tag="ACGI5H_003759"
     CDS             complement(1383..1820)
                     /locus_tag="ACGI5H_003759"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436793.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HFG9699432.1"
                     /translation="MEDKYIVHFISKTKASMIKFIENKLSKNGLGELIPTHGNILTAL
                     YENNGILTMKEIAAKIGKDKSTVTVLVNKLINLGYLERQKCTNDKRITYIKLTKKALL
                     IEDTFNSISTQVKETAYHNITENEKQEFLRILKKINDNFKNAD"
     gene            1924..2922
                     /locus_tag="ACGI5H_003760"
     CDS             1924..2922
                     /locus_tag="ACGI5H_003760"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891143.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YhdH/YhfP family quinone oxidoreductase"
                     /protein_id="HFG9699433.1"
                     /translation="MNKKFKSLYITEEEGNFRRNIVEREVDTLPEGEVLIKVKYSSLN
                     YKDALSANGNKGVTRKYPHTPGIDASGIVESSSCDDFKIGEEVLVTGYDLGMNTSGGF
                     SEYIRVPSSWVVKLPKNLSLKEAMDYGTAGFTAALSVYKFIDSVDKNMGDVLVTGGTG
                     GVAVIATKILIKLGYSVVVSTGKLEEQKEVLLNLGVKDVIHRSEVDDNSGRPLLRPRW
                     AGVIDTVGGNTLATAIKTTNYCGAVTTCGNAGGVDFTSSVYPFILKGITLYGIDSVDC
                     PMNLRLKIWDLLSNEWKLDDLDDMVNVVSLEELNDSIDSIMAGKHVGRTVVDLEKI"
     gene            complement(3042..3968)
                     /locus_tag="ACGI5H_003761"
     CDS             complement(3042..3968)
                     /locus_tag="ACGI5H_003761"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436788.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbon-nitrogen hydrolase family protein"
                     /protein_id="HFG9699434.1"
                     /translation="MSKENKNVRIAVVQASPVIMDLEKTVEKALGLIKEAGRKGANIV
                     VFPEAFIPAYPRGLSFGFVVGSRTMEGREDWKRYYDNSVPVPSATTDLLGKAAQEAGV
                     YLSMGITERDGNDINCTLYCTNLFFSPEGKLIGKHRKLKPTGTERCIWGEGDGSTLTV
                     VDTPYGKMGSLICWENYMPLARTALYAKGVKLYIAPTADSREEWQATMKHIALEGRCF
                     VIGCNQYVEKNMYPTDLNYYKELDAEPEIMCPGGSCIVDPFGKYVAGPIFNKEEMLIA
                     DLDLEKIVLSRLDFDSEGHYSRPDVFELIVHE"
     gene            4353..5957
                     /locus_tag="ACGI5H_003762"
     CDS             4353..5957
                     /locus_tag="ACGI5H_003762"
                     /EC_number="3.5.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898010.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016810 - hydrolase activity, acting on
                     carbon-nitrogen (but not peptide) bonds [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="amidohydrolase"
                     /protein_id="HFG9699435.1"
                     /translation="MKEKIYYNGNIITMEDSICGDAILIKDKIIKKIGTKEEVFALKN
                     KDTEIIDLQGKTLMPSFIDSHSHLIAFATTLKLVPLEDATSFKDIVKKIQDFKESNNI
                     KKGDWIIGFSYDNNFLEENKHPDKSVLDSASSENPILISHASGHMGVANTLGLKQLGV
                     TNETRDPEGGHIGRVEGSEEPNGYLEENAFFNVASKIKQPSSNEIFNSIEKAQNIYLS
                     YGITTAQEGLMEENQFNILKAMANQNKLKMDVVGYVNLKKSKSVADNNREFIKKYINR
                     FKIGGYKIFLDGSPQGKTAWLSRPYENSDDGYCGYPIYKDEEVEKFIDISLKEKMQLL
                     THCNGDAAADQLIDAFEKVLNLKEQSSENHIRPVMIHAQTVREDQIDDMKVINMIPSY
                     FVAHTYYWGDIHIKNLGEDRAFKISPLKTTIEKGLIYTLHQDTPVIAPNMLETVWCAV
                     NRITKKGIQIGENEKISPLDALKGVTINAAYQYFEEDKKGSIKEGKLANLIILDENPL
                     TIDPMKIKDIKVLQTIREGEVLYSLK"
BASE COUNT         2397 a          791 c          978 g         2254 t
ORIGIN      
        1 atattgcaaa tatgtttatg aaaaaggata ttaataaaga atttgacatt gattttattc
       61 tcagtaaaga agttatatgt aattatacca aagaaatatt tcaaaattta tataaaaaag
      121 aacaaagcat aggtaaaaaa gaactgctta tattgagcat aatagagaag tttttagtta
      181 aatctataat aacttttgaa gagttaaaat tgatagtgaa tataatagaa gaaaatttta
      241 catcaatata caatgaaagt ggaaagattt atttgtttag aaagtttgga gttccattcg
      301 tagtaggatg tctggattat aaaaaagtaa agtttgaaaa agatgtagtt aagattattg
      361 aggttgactt gacaaaagaa ataaatgata taagtataaa gttatcatag tgtattatct
      421 tatataatgt attataataa tctacttaaa atacacttta tttaaatatt tagtttaaag
      481 atgagatttt atgtgagtgt gtaaaagtta aagatagatt taagtaggtt atagggatta
      541 gtaaacaata aaatgaacca tgatgaacta ctataaattg tatttaaact acattttcta
      601 cttatagtaa tatcaatggt tcattttatt gttattaaga taatacagta tttataaaaa
      661 tacttgatat aaatatagta aattgtttaa atagaattat tgccttaatt tattcaaata
      721 atgagttttt aaaatctaag aaatatcctt gtggatgaag acatacagga caagctttag
      781 gagcttcttt acctatatgt atatggccac aatgtgtaca tatccattgt atatcttcat
      841 ttcttctgaa taaagtacct tcttctaaat cagtagcata tctaccaaat ctatcaccat
      901 gaactttttc tatttcagct atattttcaa ataacttagc tatagattca aatccttctt
      961 cacgtgctgt ttttccaaag tttttatata catcatccca ctcttgaagc tcattatgtt
     1021 gtgcagcttt aaggtgttgt gctgtcttgt catataaatc tacagggtat gctcctgata
     1081 tacttatatt ttcaccagca aattctttta atttagaaaa gaattgtttt gcatgtgatt
     1141 tttcttggtc agcagtgtaa ttaaataaag actctattat atataatcct tctttttttg
     1201 ctacagatgc agaaatattg tatctatttc tagcttgact ctcacctgca aaagctctta
     1261 ataaattttc tttagtttta ctatctttta aattcatatt ctacctctct atcacaataa
     1321 atttttacaa tatttgattc tttttattta ttattccaat aggagatata attatgctca
     1381 atttagtcag catttttaaa attatcatta atttttttta aaattctaag aaattcttgt
     1441 ttttcatttt ctgtaatatt atggtatgcc gtctctttaa cttgtgttga gatgctatta
     1501 aaagtatctt ctataagcag tgcctttttt gtaagcttta tatacgtgat acgtttgtca
     1561 tttgtacatt tttgtctttc taaatatcct aggtttataa gtttattaac caacactgta
     1621 acagtggatt tatcttttcc tattttagct gcaatttctt tcattgtaag tattccatta
     1681 ttttcataaa gtgcagttaa aatatttcca tgagtaggta ttaactcacc taaaccattt
     1741 ttactgagtt tattttcaat gaatttaatc atactagcct ttgttttact tatgaaatgt
     1801 acaatatatt tatcttccat aaattattct ccaatcttta atctatttaa attagtttga
     1861 cataaaacta tttataaact ataattagtt taacataaaa ctaaatgtat tgggaggaaa
     1921 tttatgaata aaaaatttaa atcactatat attacagaag aagaaggaaa ttttagaaga
     1981 aatatagttg aaagagaagt ggatacattg ccagaaggcg aagttctaat aaaagtaaaa
     2041 tattcttctc taaattacaa ggatgcactt tctgcaaatg gtaataaggg tgttacgaga
     2101 aagtatcctc atacaccagg aattgatgca tctggtatag tagaatctag tagttgtgat
     2161 gattttaaaa ttggagaaga agttttagta acaggttatg acttgggaat gaatacttct
     2221 ggtggttttt cagaatacat aagagttcct tctagttggg tagttaaact tcctaaaaat
     2281 ctttcactaa aagaagcaat ggattatggt acagcagggt ttacagcagc tttatctgtg
     2341 tataaattta tagattctgt agacaagaat atgggagatg tattagtcac tggtggtact
     2401 ggaggagttg ctgtaattgc aactaaaata ttgattaaat taggttattc agttgtagtt
     2461 tcaacaggaa aattagaaga acaaaaagaa gtattactaa acttaggtgt taaagatgtt
     2521 atacataggt cagaagtgga tgataactca ggaagacctc tgcttagacc aagatgggct
     2581 ggagtaatag atacagtagg aggaaatact ctagcaacag caataaagac aactaattat
     2641 tgtggagcag taacaacttg tggtaatgca ggaggagttg attttacaag ttcagtatat
     2701 ccatttatct taaagggaat tactttatat ggtatagatt ctgtggattg cccaatgaac
     2761 ttaagattaa aaatatggga tttattatca aatgaatgga aattagatga tttagatgat
     2821 atggtaaatg tagtatcatt ggaagagtta aatgatagta tagattcaat aatggcagga
     2881 aaacatgttg gaagaacagt agttgattta gaaaaaatat aggtgaataa atttataatt
     2941 aggattatag gttttaagca aaaatgagat acttgaaatt tacttgtgag tatctcattt
     3001 ttttatgtaa aaagatttat gtagatgttt gtgtaaaaag attattcatg aacaattaat
     3061 tcaaatacat ctggtcttga atagtgacct tctgaatcaa aatctagtct actaagtact
     3121 attttttcta ggtctaaatc agctattagc atttcttctt tattgaaaat aggacctgct
     3181 acatattttc caaaagggtc aactatacaa cttcctcctg gacacataat ttctggttct
     3241 gcatctagct ctttatagta gttaaggtca gttggataca tatttttttc aacatattga
     3301 ttgcatccaa ttacaaaaca tcttccttct aaagcaatat gcttcatagt tgcttgccac
     3361 tcttctcttg aatctgcagt aggggctatg taaagtttta cacccttagc ataaagagct
     3421 gttctagcta atggcatata attttcccaa caaatcaacg aacccatttt tccatatgga
     3481 gtatcaacta ctgtaagagt acttccatct ccttctcccc aaatacatct ttctgttcct
     3541 gtaggtttaa gttttctgtg tttaccaatt agcttacctt ctggagagaa aaataagttt
     3601 gtgcaataaa gggtacaatt tatatcatta ccatctcttt ctgttatacc cattgataga
     3661 tatactcctg cttcttgtgc tgcttttcct aataaatctg ttgtagcact aggaactggt
     3721 acagaattat catagtatct tttccaatct tctctacctt ccattgttct acttccaaca
     3781 acaaatccaa atgaaagacc tcttggatat gcaggtatga atgcttcagg gaaaactacg
     3841 atatttgccc cttttctacc agcttcttta attaatccta atgctttttc aacagttttt
     3901 tctaaatcca ttatgactgg tgacgcctgg acaacagcaa ttcttacatt tttattttcc
     3961 ttgctcataa aaacctccta aaaaatattt aaattttttg cattgaatag attacatgag
     4021 atgttatttg agaactaaga tacttatatt gtgaataata atgtaactgt atatttaaaa
     4081 taatacatca tgatttaaaa aattacaatt gtacagatat aattgagttt agatatttaa
     4141 atttaacaac ttataatatt ttttcaatta gtataaagcc tattaatttg tcttatttac
     4201 aatgaatagt atttacttct tggcaaacaa taattaaaaa taaaactttt atatgattaa
     4261 actctaaaga aaaagtttat aaagaagata atataattaa gcagaaaata atgaaaaaaa
     4321 tttattaaag tagacaacgt aaggagaatt ttatgaaaga aaaaatttat tacaatggaa
     4381 atatcatcac aatggaagat tcaatatgtg gagatgctat tcttataaaa gacaaaataa
     4441 taaaaaagat aggaacaaaa gaagaagtat ttgctttgaa aaataaagat acagaaatta
     4501 tagatttaca aggtaagaca ttgatgccat cttttataga ttcacatagt cacttgatag
     4561 cttttgctac tactctaaag ctagttcctt tagaagatgc aaccagtttt aaagacatag
     4621 taaaaaaaat acaggatttc aaagagtcga ataatataaa aaaaggagac tggataattg
     4681 gattttcata tgataataat tttttagaag aaaataagca tccagataag agtgtactcg
     4741 atagtgcatc ttcagaaaat ccaatactaa tttcacatgc ttctggtcat atgggagttg
     4801 caaatacatt ggggttaaaa cagcttggtg ttaccaatga aacacgtgac ccagaaggtg
     4861 gacatatagg tagagtagaa ggcagtgaag aaccaaatgg atatttagaa gaaaatgcat
     4921 tttttaatgt agcatctaaa ataaaacaac catcatcaaa tgagattttt aattcaattg
     4981 aaaaagcaca gaacatatat ctaagctatg gtattacaac agctcaagaa ggtttaatgg
     5041 aagaaaatca atttaacatt ttaaaagcaa tggcaaatca aaataaatta aaaatggatg
     5101 ttgtaggata tgtaaatttg aaaaaaagta agtctgtagc agataataat agggagttta
     5161 taaaaaaata tataaataga tttaaaatag gaggttataa gattttctta gatggttctc
     5221 cacaaggtaa gacagcatgg ttgagtagac catatgaaaa ttcagatgat ggttattgtg
     5281 gatatcctat atacaaagat gaagaagtag aaaagtttat agatatttca ctaaaagaaa
     5341 agatgcaact cttaactcat tgtaatggag atgcagcagc agaccagttg atagatgcgt
     5401 ttgagaaagt tttaaattta aaagagcaaa gtagtgaaaa tcatataaga ccagttatga
     5461 tacatgctca aacagtaaga gaagaccaga ttgatgatat gaaagtaata aatatgatac
     5521 cttcatactt tgtagctcac acatattatt ggggtgatat tcatatcaaa aaccttggag
     5581 aagatagagc gtttaagatt agcccactta aaacaactat agaaaaggga ttaatttaca
     5641 ctcttcatca ggatacacca gtaatagcac ctaatatgct ggaaacagta tggtgtgctg
     5701 tcaatagaat tacaaaaaaa ggtatacaaa taggagaaaa tgaaaagata agcccattag
     5761 atgctttaaa gggtgttact ataaatgcag catatcaata ttttgaagaa gataaaaaag
     5821 gttcaattaa agaagggaaa ttagctaatt tgataatctt agatgaaaac ccacttacaa
     5881 tcgaccctat gaaaataaaa gatattaaag tattgcagac tataagagaa ggagaagtat
     5941 tgtattcttt gaagtagatg aaagttagat attttataat ctataaaaaa tagttttata
     6001 taataagtta ggtagaatta aataagatta cagttaaatc aacaattata tttttattaa
     6061 attttaatta ttgtattgaa gatttataag tataatttta ttgattctac ctttttaaat
     6121 aactgtcgat ttattaaagt tatctatgta ctatattaaa caattaagta gttattaatt
     6181 gaacttatta gtttattaaa aaactatgta tattactttg cagtaagact ttggaactaa
     6241 atctataata gcaaatttaa atttattaaa tagattacct tataacattt catataaaat
     6301 atattgtgaa tctgagaaaa ttactatttt tctttgagta ttttttgtaa gcagttctaa
     6361 aagattcaat ttcataccta ttacttgaat cattcattaa aataattcta atttaaaaaa
//
LOCUS       DAYAOO010000153         6295 bp    DNA     linear   BCT 12-OCT-2024
DEFINITION  TPA_asm: Clostridioides difficile isolate ST8-SSI-h139-18
            SAMN40601845-rid21577343.denovo.157, whole genome shotgun sequence.
ACCESSION   DAYAOO010000153 DAYAOO010000000
VERSION     DAYAOO010000153.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN40601845
            Sequence Read Archive: SRR28438827
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 6295)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6295)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-MAY-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-MAY-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002157583.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002157583.1
            Genome Coverage       :: 163x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/11/2024 16:19:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 4,038
            CDSs (total)                      :: 3,963
            Genes (coding)                    :: 3,930
            CDSs (with protein)               :: 3,930
            Genes (RNA)                       :: 75
            rRNAs                             :: 6, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 60
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 33
            CDSs (without protein)            :: 33
            Pseudo Genes (ambiguous residues) :: 0 of 33
            Pseudo Genes (frameshifted)       :: 7 of 33
            Pseudo Genes (incomplete)         :: 25 of 33
            Pseudo Genes (internal stop)      :: 11 of 33
            Pseudo Genes (multiple problems)  :: 8 of 33
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6295
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN40601845-rid21577343.denovo.157"
                     /isolate="ST8-SSI-h139-18"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Denmark"
                     /collection_date="2018"
                     /collected_by="Statens Serum Institute"
     gene            <1..291
                     /locus_tag="ACGI5H_003763"
     CDS             <1..291
                     /locus_tag="ACGI5H_003763"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893947.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GHKL domain-containing protein"
                     /protein_id="HFG9699436.1"
                     /translation="LDNAIEACMDINNEIEKRIEVKATYINKFAIIKFINTKVNDIKL
                     IDKRIQTSKDDDKIHGIGLASIKYIVNKYGGETIVNYSDNEFILKIMIPIKS"
     gene            303..443
                     /locus_tag="ACGI5H_003764"
     CDS             303..443
                     /locus_tag="ACGI5H_003764"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437290.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cyclic lactone autoinducer peptide"
                     /protein_id="HFG9699437.1"
                     /translation="MKKIALNLLKNISALSFGIAVLSANSASSWVAHQAKEPQALQKL
                     KK"
     gene            502..1083
                     /locus_tag="ACGI5H_003765"
     CDS             502..1083
                     /locus_tag="ACGI5H_003765"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891808.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="accessory gene regulator ArgB-like protein"
                     /protein_id="HFG9699438.1"
                     /translation="MFKRLSYKFANILVNNEIVESEDFEIYRYGFETLIYFIVNILVA
                     LFIGIIFDRFIHTVIFLSCYCTLRQFTGGYHARNYKECTLTFAVIYLITIFSANNIDI
                     NKYKYLLVLLMIISILTIYKLAPLEHRNKPLSESEKKHYRKTVQKILFVIICLIILCK
                     ILNIFQQYVIYAIISIYWIAILIYIGMKVNSDQ"
     gene            1230..2939
                     /locus_tag="ACGI5H_003766"
     CDS             1230..2939
                     /locus_tag="ACGI5H_003766"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018112712.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9699439.1"
                     /translation="MSSIKAISDFITKIIRKNILFAITIIIINYHLIQRWTHISNRGI
                     SFNDYLSLSVYTCMTISILTMLNVIFYMRKSYDTVKILCRNNFDYFLGISVAVTRNNF
                     IFCCIPIIYAIAYSSLIRTLSIVTIKSTIFILIFEWFLPLTILSIVISFISVIINNLI
                     LKITLSSVFLYLTSTNMLDRVIDIKEPFFKALFKSLNIFEDQSYAYYSDFVGKVNNSA
                     YVIDKIIPTLFAITLIIVAYLILNDIRKKQIKSLIVIVVYSILFIGLNYISIDMSTYR
                     DEERSYGEYLKKSNISDIKIKSHDMKIDFKSKSNIKDRIVLLNTSNEELTNINMILDE
                     IFDIKYIKINSENIKFNKKKDLIEVNLKESLEPNDEVTLDIEYEGYINVLTSWNQNKY
                     IATKDDIMLPPGSLAWYPKVNQSSCMAYKINLSSKNNVYSNLPLLNKTSNFLKKDYIF
                     EGKSNDIAIYAGEFKEEVKDDIKIIYPSDSNVNMDIEEKIKFLIETRNEILGDSKASV
                     DAKKYVDEVDNVMESIKRKKINMILVADLPSNEFLYEDSKGEKISITIYHWLSGNILI
                     IDK"
     gene            2954..3826
                     /locus_tag="ACGI5H_003767"
     CDS             2954..3826
                     /locus_tag="ACGI5H_003767"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891804.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HFG9699440.1"
                     /translation="MINKLEIRNLNFNYKNKKALDNINLTLIDGVVALLGPNGAGKST
                     LMRLLVTLYETSIGEIELNNIKYSKNNEKIKANVGYVPQDFDMYNNINGQEYLEFVAK
                     MRGVSKNDLKKHIQKVVSKVNLDKFINKKIGTYSGGVKRRLGIAQALIGDSKLIVMDE
                     PTVGLDPEQRNEFRRLLPEISKNSIVLISTHIVEDIQFNCDKLIILNQGKILYDGTIN
                     KFIDMVEVYSVVVSNDEFEYLERNIDIIDYRRVKDGVQVKYIGKNTEKLKDSLRIDTT
                     LQDAYINFLHKELK"
     gene            3827..4615
                     /locus_tag="ACGI5H_003768"
     CDS             3827..4615
                     /locus_tag="ACGI5H_003768"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437307.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9699441.1"
                     /translation="MCILELIKFELKKIELKHVLIFVIISILCIFITGILDYNELIFY
                     NDVPIMDTYSIAGWLGIIKISDVFIPIMSAITIIYVFSKDYSGNINEILTLYNKKKYN
                     QFIVFRWCVILAIYTVLLLISITIVYTFTSVKGFNIDKIDFVYSVKPIDVFLKTFPTL
                     LWYTTFPLMILTLTKNRFTTIAILITYTFADIFFILHMYPFVSMINVNGFYIQKMFYM
                     PNNIDVRFNELKNYFFINRGSLVVISIIIVSYIARKSTVLKKSK"
     gene            complement(4711..5544)
                     /locus_tag="ACGI5H_003769"
     CDS             complement(4711..5544)
                     /locus_tag="ACGI5H_003769"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891800.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prenyltransferase"
                     /protein_id="HFG9699442.1"
                     /translation="MNVENQSLSDIEIILSHRYDNGADYWTTPDKRLIKGSPFSTLDS
                     VLYLLELGVNPDDTLLKECADLIFSTWREDGRFKLYPNGGIYPCHTANAANVLCHMGY
                     ASDIRMQKTFQHFLDTQYTDGGWRCNKFSFGRGPETEYSNPLPTLNILNAFRFSNYLN
                     KESKLDKAVDFLLDHWTIKKPIGPCHYGIGTLFMQVEYPFRNYNLFLYVYVLSFYNCA
                     KKDNRFLEALKILESKMIGNKIVVERVVPKLSKLSFCKKGESSEIATTHYYEILKNLE
                     K"
     gene            complement(5612..6241)
                     /locus_tag="ACGI5H_003770"
     CDS             complement(5612..6241)
                     /locus_tag="ACGI5H_003770"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903713.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3786 domain-containing protein"
                     /protein_id="HFG9699443.1"
                     /translation="MDEKITKNNYNVPFDYVRKKLKELDPHTISNLSNIPFNNDLNRF
                     TLNFFDRQYIIDYPSGEVWNSNGSLCNNFELKILIVRYLINAKGIPRTNKYVTFKEIP
                     GGNVYYPNFLNRTLYRLSEVFTSQIDKYKLVMEKIGAEKVNMGDLAYRFTYMGNTSMV
                     FILWFGDDEFPPNSNILFDSNIVYYFNAEDLAVVPDTAINAILNKINQL"
BASE COUNT         2481 a          653 c          897 g         2264 t
ORIGIN      
        1 ctagataatg caattgaagc atgtatggat ataaataatg agatagaaaa aagaatagaa
       61 gttaaagcta catatataaa taaatttgca ataataaaat ttataaatac taaggtaaat
      121 gatattaaac ttattgataa acgtattcaa actagtaagg atgatgataa gatacatgga
      181 ataggacttg ctagtattaa atatatagta aataaatatg gtggtgaaac aatagttaat
      241 tactcagata atgagtttat attaaaaata atgataccaa taaaaagtta ggagagtaca
      301 aaatgaaaaa aatagcgtta aacttactta aaaacatctc agcattaagt tttgggatag
      361 ctgtattatc agcaaacagt gcaagttctt gggtagcaca tcaggcaaaa gagccacaag
      421 ctttacaaaa actaaaaaaa taacattaat aaaaggacct cttcttatta aaggagaggt
      481 tttacatgtt gaggaggaaa tatgtttaaa agattatcat ataaatttgc caatatatta
      541 gttaataatg agattgtaga aagtgaagat tttgaaatat atagatatgg atttgaaact
      601 ttgatttatt tcatagttaa tattttggta gcattattta taggaattat ttttgataga
      661 tttatacata cagttatatt tttaagttgt tattgcactt taagacagtt cacaggaggt
      721 tatcatgcta ggaattataa agagtgtaca ttaacatttg cagttattta tttgataact
      781 attttttcag ctaataatat agatataaat aaatataagt atttattagt attattaatg
      841 attattagta tactaacaat ttacaagtta gctcctttag aacatagaaa caaacctctt
      901 agtgaaagtg agaaaaagca ttatagaaag actgtgcaaa aaatactatt cgtaataata
      961 tgtttaatta ttttatgtaa aatacttaat atttttcagc aatatgtgat ttatgcaata
     1021 atttctatat attggattgc tatattaata tatattggaa tgaaggttaa tagtgatcag
     1081 taagattata aaacattttc taaattaatt aacttcacta attaatatta actttaaaaa
     1141 aataatgtca aggtaagtat ttgaacttat taaatatagt tgaatctatt gtaggttgta
     1201 tcaaaagact ggctaggagg ggcataaata tgagtagtat taaggctata tcagacttta
     1261 taaccaaaat aattagaaaa aatattttat ttgcaataac aattattatt ataaattacc
     1321 atctcataca acgatggaca catatatcca atagaggaat ttcatttaat gattacttat
     1381 ccttgagtgt atatacttgt atgacaatta gtattttaac catgttaaat gtaatttttt
     1441 atatgagaaa aagttatgat actgtaaaaa tattatgtag aaataatttt gattattttt
     1501 taggtatttc tgttgctgta actagaaaca actttatatt ttgttgcata ccaattatat
     1561 atgctatagc atactcaagt ttaataagaa cattgtcaat tgtaacgatt aaatcaacta
     1621 tatttatatt gatatttgaa tggtttttac cacttactat tttatctata gtgatatcat
     1681 ttatttcagt tattataaat aatttaatac taaagattac cttatcatca gtatttttat
     1741 atttaacatc aactaatatg ttggatagag ttattgatat taaagaacca ttttttaaag
     1801 cattatttaa atcacttaac atatttgaag atcaatcata tgcttactat tctgattttg
     1861 tagggaaagt taataattca gcatatgtta tagataagat tatacctaca ctatttgcaa
     1921 ttactttaat aatagtagca tatctgatat taaatgatat tagaaagaaa cagattaaat
     1981 cattaatagt tatagtagtg tacagtattt tatttattgg attaaattat atatcaatag
     2041 atatgtcaac atatagagat gaggagcgta gttatggaga gtatttaaag aaatctaata
     2101 ttagtgatat taaaataaaa tcgcatgata tgaagattga ctttaaaagc aagtcaaata
     2161 taaaagatag aattgtttta ttaaacacat caaatgaaga gttaacaaat attaatatga
     2221 ttttagatga aatatttgat ataaaatata taaaaataaa ttcggaaaat ataaaattta
     2281 acaaaaaaaa ggatttaatt gaagttaatt taaaggaaag tttagagcct aatgacgagg
     2341 tgacattaga tatagagtat gaaggctata ttaatgtgtt gacatcttgg aatcaaaata
     2401 aatatatagc tactaaagat gatattatgc ttccaccagg ttctttagcg tggtacccaa
     2461 aagtaaatca atcaagttgt atggcttata aaataaattt aagttctaaa aataatgtct
     2521 attcaaattt acctttactg aataagacta gtaatttttt aaaaaaagat tatatatttg
     2581 aaggaaagtc aaatgatatt gcaatatatg caggtgagtt taaagaagag gtaaaagatg
     2641 atataaaaat aatctatcca tcagatagta atgtaaatat ggatatagag gaaaaaatta
     2701 aatttttaat tgaaacaaga aatgaaatat taggtgatag caaagcatct gtagatgcta
     2761 aaaaatatgt agatgaagta gataatgtta tggaatcaat aaaaagaaaa aaaattaata
     2821 tgatattagt tgctgactta cctagcaatg aatttttata tgaagactca aagggagaga
     2881 aaattagcat aactatttat cattggcttt caggaaatat ccttataata gataaataat
     2941 aaaggaggtt aatatgataa acaagttaga aataagaaat ctaaatttta attacaaaaa
     3001 taaaaaagct ttggataata taaatttaac cctaatagat ggagtagttg cattattagg
     3061 tcctaatggt gctggaaaat caacattaat gaggttatta gtgactcttt atgaaacttc
     3121 aattggagag atagaattaa ataatataaa gtatagcaaa aacaatgaga aaatcaaggc
     3181 aaatgtagga tatgtacctc aagattttga tatgtataat aatataaatg ggcaagaata
     3241 cttagaattt gtagctaaaa tgagaggtgt atctaagaat gatttaaaga aacatataca
     3301 aaaagtagta tcaaaagtta atctggacaa gtttataaat aaaaaaatag gtacatactc
     3361 aggtggtgta aagagacgac taggtatagc acaggcttta ataggtgatt ctaagttaat
     3421 agttatggac gaacctacag ttggtcttga tccagagcaa aggaatgaat ttagaagatt
     3481 gttaccagaa ataagtaaaa attctatagt attaatttca actcacatag tagaagacat
     3541 acaatttaac tgtgacaaat taattatatt aaatcaaggc aaaatattat atgatggtac
     3601 aattaataag tttattgata tggttgaggt gtattcggta gtagtttcta atgatgaatt
     3661 tgaatattta gaacgtaata ttgatattat tgattatagg agagttaaag atggtgtgca
     3721 agtaaagtat ataggtaaaa atacagagaa acttaaagat agcttaagga tagatacaac
     3781 tttacaagat gcttatataa actttttaca taaggagtta aaataaatgt gtatattgga
     3841 gttaataaaa tttgagctta aaaaaataga gcttaaacat gtgttaatat ttgtaattat
     3901 ttctatctta tgcatattta ttacaggcat attagattat aatgagttaa tattttataa
     3961 tgatgtacct ataatggata catattctat agcaggatgg ttaggaatta taaagatatc
     4021 agatgttttt ataccaataa tgtcagcaat cacaataatt tatgtgtttt caaaagatta
     4081 ttcgggtaat ataaatgaga tacttacttt atataataaa aaaaaatata atcaatttat
     4141 agtatttaga tggtgtgtta tattagctat atatactgta ttattattaa tttcaattac
     4201 aatagtatat acatttacgt cagtgaaagg ttttaacata gacaaaatag attttgttta
     4261 tagtgtaaag ccaatagatg tgtttttaaa gacatttcct acattattat ggtatacaac
     4321 atttccacta atgatattaa cattaacaaa aaatagattt acaacaatag caatattaat
     4381 tacatataca tttgctgata tattttttat tttacatatg tacccatttg ttagtatgat
     4441 taatgtaaat ggattttata ttcaaaagat gttttatatg cctaacaata tagatgttag
     4501 atttaatgaa ttaaagaatt atttctttat aaatagaggt tctctagtag ttatttctat
     4561 aataatagtt tcttatatag caagaaaatc aacggtttta aaaaagagta aatagtttaa
     4621 tatatttttt ataatgttat atttatatag aatagtgact ttaaaaaatt taaagccact
     4681 attttttaat atgttttatc tatataacta ttatttttct aggtttttta atatttcgta
     4741 atagtgtgtt gtggctattt cacttgactc gcctttttta caaaaagata atttagatag
     4801 ttttggaact acacgttcaa cgacaatttt attacctatc attttagatt caagtatctt
     4861 caatgcttct aaaaatctat tatccttttt tgcacaatta taaaatgata aaacgtagac
     4921 ataaaggaat aggttataat tacggaaagg atattcaact tgcataaata aggttccaat
     4981 tccatagtga caagggccga ttggtttttt aatagtccaa tggtcaagta gaaaatctac
     5041 agctttgtca agttttgatt ctttatttag ataattacta aaacggaatg catttaatat
     5101 attaagagtt ggtagtggat ttgagtattc agtttctgga cctcgaccaa aactaaattt
     5161 attgcaacgc cacccaccat cagtatactg tgtatctaaa aaatgttgaa acgttttttg
     5221 cattctaatg tcagatgcat atcccatatg acagagtacg ttagcagcat ttgcagtatg
     5281 acaagggtaa atacctccat ttggatatag tttgaaacgt ccatcttctc gccatgtgct
     5341 aaatatcaag tcagcacatt ctttaagtaa agtatcatca gggttcacac ctaattctaa
     5401 tagataaagt acactatcaa gagtagagaa aggagaacct tttattaaac gcttatcagg
     5461 tgtagtccaa tagtctgcac cattatcata cctgtgtgat aatattattt caatatctga
     5521 taaagattga ttttctacat tcatttttta ctccatttca tattatattc tattaaatct
     5581 atcaaaaact ttattataat attatttata tttataattg atttatttta tttaaaattg
     5641 catttatagc tgtatcagga acaactgcta aatcttctgc attgaagtaa taaactatat
     5701 tagaatcaaa taatatattt gaatttggag gaaattcatc atctccaaac caaagtataa
     5761 ataccataga tgtattaccc atatatgtaa acctataagc taaatctccc atgtttactt
     5821 tttcagctcc aattttctcc ataactaact tatatttgtc tatttgagat gtaaaaactt
     5881 ctgaaagcct atatagagtc ctgtttaaaa aatttggata ataaacattg cctcctggta
     5941 tttctttaaa agttacatat ttattagttc taggaatacc tttagcattg attaaatatc
     6001 taactatcaa gattttaagc tcaaagttat tgcaaaggct accattacta ttccaaactt
     6061 ctccacttgg atagtctata atatattgtc tatcaaaaaa attgagtgtg aatctattta
     6121 aatcattatt gaaaggtata ttacttaaat tactaattgt atgagggtct aattctttga
     6181 gtttttttcg aacatagtca aatggaacat tataattatt ttttgttatc ttttcatcca
     6241 taattttttc ctccaattta aacaattaaa agtatattta taaaaagttt tctta
//
LOCUS       DAYAOO010000154         6288 bp    DNA     linear   BCT 12-OCT-2024
DEFINITION  TPA_asm: Clostridioides difficile isolate ST8-SSI-h139-18
            SAMN40601845-rid21577343.denovo.158, whole genome shotgun sequence.
ACCESSION   DAYAOO010000154 DAYAOO010000000
VERSION     DAYAOO010000154.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN40601845
            Sequence Read Archive: SRR28438827
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 6288)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6288)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-MAY-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-MAY-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002157583.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002157583.1
            Genome Coverage       :: 163x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/11/2024 16:19:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 4,038
            CDSs (total)                      :: 3,963
            Genes (coding)                    :: 3,930
            CDSs (with protein)               :: 3,930
            Genes (RNA)                       :: 75
            rRNAs                             :: 6, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 60
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 33
            CDSs (without protein)            :: 33
            Pseudo Genes (ambiguous residues) :: 0 of 33
            Pseudo Genes (frameshifted)       :: 7 of 33
            Pseudo Genes (incomplete)         :: 25 of 33
            Pseudo Genes (internal stop)      :: 11 of 33
            Pseudo Genes (multiple problems)  :: 8 of 33
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6288
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN40601845-rid21577343.denovo.158"
                     /isolate="ST8-SSI-h139-18"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Denmark"
                     /collection_date="2018"
                     /collected_by="Statens Serum Institute"
     gene            178..1059
                     /gene="pepI"
                     /locus_tag="ACGI5H_003771"
     CDS             178..1059
                     /gene="pepI"
                     /locus_tag="ACGI5H_003771"
                     /EC_number="3.4.11.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729000.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004177 - aminopeptidase activity
                     [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="proline iminopeptidase"
                     /protein_id="HFG9699444.1"
                     /translation="MKITEGYMPFKGFKTYYRIVGENTEGKKPLVLLHGGPGSTHNYF
                     EVLDKIAESGRQVIMYDQIGCGNSFVEGHPELFNADTWIEELIELRKHLGLDEIHLLG
                     QSWGGMQAIWYAIEYKPKGIKSYILSSTLSSAKLWEKEQKRRISYMSEVDQKALLDAV
                     NTGDYSSKEYNDALERFMEMYCAGEVTEDSPECLRRPKKSGSEAYIVGWGQNEFSPTG
                     TLSGYEFTDRLHEIKEPCLVTSGAIDLCSPYIAKTMYDRIPNSKWELFEYSRHMPFVE
                     ENEKYIKVLTEWLNAND"
     gene            1441..2244
                     /locus_tag="ACGI5H_003772"
     CDS             1441..2244
                     /locus_tag="ACGI5H_003772"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003432058.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9699445.1"
                     /translation="MEKLRVIEMIKNNPNIIATIDNPTDEMKLLAIKENGLVLEYINN
                     PTREMQELAIDNNIRAIKFIDNPTEDMMIKAVNEGWSILDYIKNPTDKVIEMAINQAG
                     WAIKYAKNPSEELQLLAVRKNYDSIKFIKQPYESVQEEAVRISYDALRYIDSPSYNAE
                     LIAIKNNEAAISFITDLDKNKMLEFLKVNILVIKYILKKVSKDELESALKEVLSKEDV
                     EEKYIRDFLNCSVIDRNSESIPIDKIMFIYKYGSKTAKKIAVDEKLKIM"
     gene            2256..3386
                     /locus_tag="ACGI5H_003773"
     CDS             2256..3386
                     /locus_tag="ACGI5H_003773"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422548.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HFG9699446.1"
                     /translation="MNFIDTLKSVDLILSTGEVPLIVGESGIGKTALANKLAKENDWS
                     LIVIDGNLLKEGEIGGLPTIESYVGVNSNGYKTEKKTTVYAVHNKLREIDEEISKSKT
                     VLLFIDEINRCEHTVQQELMNLILNREINGYKLHDDVKILAAMNPSSKYGSDFDYQVV
                     DMDAAQENRFVWLNMESDHTQWIKWAIDEGIERKVIEFISTFPEYLHKINEDDVRATP
                     RSYERVSKIYKVYKEKNNSIPRAVFLNVVKGNVGKVIAEEFISFIESNSEPLISYEDV
                     FLGESIDESIVERVKNESHTRLYLSAMNILKDLELNIKNDKYESNHYINRFIEFLKMY
                     PVDLMIGIMKDIRNSYIEVYKKAIENEEFVKSYFESYSLIRG"
     gene            3390..4799
                     /locus_tag="ACGI5H_003774"
     CDS             3390..4799
                     /locus_tag="ACGI5H_003774"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903420.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VWA domain-containing protein"
                     /protein_id="HFG9699447.1"
                     /translation="MENYFDKQAKELYNKASEIINTHSMLKANRANEKFDIDIPQDFK
                     YEFFSLVDKVNLSLMEEEDNFYGYFLFQMSREIRFDISSPTGVNFKGAKYIIYFNPII
                     FLTLDIKQMETTIKHEIHHILSMHLMRAKELKGKYSTLAINMAMDIVVNKFLNNLPPY
                     ATTLEWVNLKYSLKLEPYEPFEYYVEKIQTELDLMEVDEDGEEDDSDKYGDIEIDYSP
                     ERTHDIWDESNEIDENTLREFTEKFINSSQKGKVPAYLESMISSLKNSKGELPWNLYL
                     NRIMGTVENNKKKTITRRNRRQPNRLDLRGELRSHKSEIAVALDVSGSISDEEFKQAI
                     KEVLSIVKNYNHEITIIECDNEIRRVYKVRTEKDIKDRIRIGGGTRFSPVFEYANNKK
                     INLLVYFTDGKGENKLQVIPRGYKILWVISGRGDKISLKEPYGAVKKLTKVKTNDEIL
                     EINDVRNDGYSMNSQAPIL"
     gene            5016..5519
                     /locus_tag="ACGI5H_003775"
     CDS             5016..5519
                     /locus_tag="ACGI5H_003775"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422552.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CarD family transcriptional regulator"
                     /protein_id="HFG9699448.1"
                     /translation="MFLFKIDDYIMYGMTGVCKVMDITNERFTNGIKKEYYVLSPIYS
                     NNTVIKIPVDNEKVPMRKLLSKINVLSLINDIPNMDTSWIDNEKLRSEQFKKILRGGK
                     CEELIKLVRSIDNNREYVKSIGKKTHQADDNIMKEAERLLNEEFATILDISPNEVSSY
                     ISSHIPQ"
BASE COUNT         2559 a          555 c         1108 g         2066 t
ORIGIN      
        1 atagttaata taattttata attggtttag tatagagatt tttaactttt atgttatact
       61 atttataaaa gtaggtataa agattaaaat acataatcaa atatgtataa gaggttttaa
      121 atagtattgt taatgaactt gattattgtt tataattaca aattggagga gataaacatg
      181 aaaattactg aaggatatat gccttttaaa ggttttaaaa cgtattaccg tatagtagga
      241 gaaaatacgg aagggaagaa gccattagta ttacttcatg gaggtccagg ttctacacac
      301 aactattttg aggtattgga taagatagct gaaagtggta gacaagtaat aatgtatgac
      361 caaattggtt gtggaaattc atttgtagaa gggcatcctg agctatttaa tgcagatact
      421 tggatagagg agcttattga actaagaaaa catctaggac ttgatgaaat tcatctgtta
      481 ggtcaatctt ggggaggtat gcaggctatt tggtatgcta ttgaatataa accaaaaggt
      541 attaagtctt acatcctttc atctactctt tcttctgcaa aactttggga gaaagaacaa
      601 aaaagaagaa tatcatatat gagtgaggtt gaccaaaaag cattacttga tgcagtaaat
      661 actggagatt actctagcaa agaatataat gatgcattag aaagatttat ggaaatgtat
      721 tgtgcaggtg aagtgacaga agattctcca gagtgcctga gaagacctaa aaaatcaggt
      781 tctgaagcat atattgtagg atggggacaa aatgaatttt ctcctacagg aactctttct
      841 ggatatgaat ttacagatag attacatgaa ataaaagagc cttgtctagt aactagtgga
      901 gcaatagatt tatgttcacc atatattgca aagactatgt atgatagaat acctaatagt
      961 aagtgggaat tatttgagta ttcaagacat atgccattcg ttgaagaaaa tgagaaatat
     1021 ataaaagtct taactgagtg gttgaatgcg aacgattaaa aactatataa atttatataa
     1081 aaaaatgagt gtctcaaaat gaacttttta gttcattagg cactcttttt gcatgaaatc
     1141 aaatatattt tcattatttg aacgataaaa tgaggcttat atctattttg ggaaagtaat
     1201 tttttattac tagcgttaga ttctaatcta attgtatact tattgaaata atagaaatat
     1261 attggtgttt ataacttaat tttattgttt tttagaaatt tttttatata ttggtataat
     1321 tattctgttt aaatttgatt aaaaagtata ttaattataa taagaaacaa ttatataaat
     1381 aggaatagat tattataatt aatatagata taaaaataat tatagaagga aaggcacatt
     1441 atggaaaaat tgagagttat tgaaatgata aaaaataatc ccaatattat agctacaata
     1501 gataatccaa ctgatgaaat gaaattgtta gctattaaag aaaatgggct tgtactagaa
     1561 tatataaata atccaaccag agagatgcaa gaactagcaa tagataataa tattagagca
     1621 attaaattta tagataatcc aacagaagat atgatgataa aagcagtaaa tgagggatgg
     1681 agtatactgg attatatcaa aaacccaact gataaagtta ttgaaatggc tataaatcaa
     1741 gcaggatggg caattaaata tgctaaaaat ccaagtgaag aattacaact gttagcagta
     1801 agaaaaaatt atgattcgat aaagtttata aaacaacctt atgaaagtgt acaagaggag
     1861 gcagtgagaa taagttatga tgccttgaga tatatagatt cacctagtta taatgcagaa
     1921 cttatagcta taaaaaataa tgaagcagct attagcttta taactgattt agataaaaat
     1981 aaaatgttgg aatttttaaa agtgaatatt ttagtgatta agtacattct gaaaaaagta
     2041 tctaaagatg aattagagag tgcattaaaa gaagtattat ccaaagaaga tgttgaggaa
     2101 aagtatatta gagatttttt gaattgtagt gttatagata gaaatagcga aagtatacca
     2161 atagataaaa ttatgtttat ttataaatat ggaagtaaga cagcaaaaaa aatagctgta
     2221 gatgagaaat taaagattat gtaggagaga gaaaaatgaa ttttatagac acattaaaaa
     2281 gcgttgactt aatattatcc actggagaag tacctttaat agtaggtgaa agtggaatag
     2341 gaaaaacagc tttagcaaat aagcttgcca aagaaaatga ttggagttta attgttattg
     2401 atggaaactt acttaaagag ggtgaaatag gtggtcttcc aactatagaa tcttatgtag
     2461 gagttaattc taatggatat aagactgaaa agaaaacaac agtgtatgct gttcataaca
     2521 aattaagaga aattgatgaa gagatatcta aaagtaagac agttctttta tttatagatg
     2581 agataaatcg ttgtgagcat acagtacagc aagaacttat gaatttaatt ttaaatagag
     2641 aaattaatgg atataaactg catgatgatg taaagatttt agcagcaatg aatccatcaa
     2701 gtaaatatgg ttcagatttt gattatcaag tggtagatat ggatgcagcc caagaaaata
     2761 ggtttgtttg gttaaatatg gagagtgacc atacacaatg gataaaatgg gcaatagatg
     2821 agggtattga aagaaaagtt atcgagttta tttccacttt tccagaatat ctgcataaaa
     2881 taaatgaaga tgatgtaaga gccactccta gaagttatga gagagtatct aaaatttata
     2941 aagtttataa agaaaaaaat aattctattc ctagagcagt atttttaaat gttgtaaagg
     3001 gtaatgtagg taaagttatt gcagaagaat ttataagttt tattgaatca aactctgaac
     3061 cattaatatc ctatgaagat gtttttttag gagaatctat tgatgagtct attgtagaaa
     3121 gagtaaaaaa tgagagtcat acaagacttt atctatcagc tatgaacatt ctaaaagact
     3181 tagaattaaa tattaagaat gataaatatg aatcaaacca ctatattaat agatttattg
     3241 aatttttaaa aatgtatcct gtagatttaa tgataggtat tatgaaggat attagaaaca
     3301 gttatattga agtatataaa aaagctatag aaaatgaaga gtttgtaaaa tcatattttg
     3361 aatcttatag tttaataagg ggataatgta tggaaaatta ttttgataaa caagcaaaag
     3421 agctttataa taaagcaagt gaaattataa atactcattc tatgctaaag gcaaatcgtg
     3481 ctaatgagaa atttgatata gatataccac aagattttaa gtatgagttt tttagtcttg
     3541 tagataaagt gaatttaagt cttatggaag aagaagataa tttttatgga tattttttgt
     3601 ttcagatgtc aagagaaata agatttgata taagtagtcc tacaggtgtg aattttaagg
     3661 gagctaaata tattatatat tttaatccaa taatcttttt aacgcttgac ataaagcaaa
     3721 tggagactac aattaaacat gaaattcatc atatattatc tatgcatttg atgagagcaa
     3781 aggagttaaa aggaaagtat agtacattag caattaatat ggcaatggat atagtagtaa
     3841 ataaatttct aaacaattta ccaccatatg caactacctt agagtgggta aatttaaaat
     3901 attccttaaa acttgaacca tatgaacctt ttgaatatta tgtagaaaag attcagactg
     3961 aattagattt gatggaagtg gatgaagatg gtgaggaaga tgatagtgat aaatatggag
     4021 atatagaaat tgattatagc cccgaaagaa ctcatgatat atgggatgaa tccaatgaga
     4081 tagatgaaaa tacccttaga gaatttactg aaaaatttat taacagttct caaaaaggta
     4141 aagttcctgc ttatttagaa agtatgatat catcacttaa aaatagtaag ggtgaattgc
     4201 catggaattt atatcttaat agaataatgg gaacagttga aaataataaa aagaagacta
     4261 taacaagaag aaatagaaga caaccaaatc gtttagattt gaggggagaa cttagaagtc
     4321 ataagtcaga aatagcagtt gcacttgatg taagtggaag tattagtgat gaagagttta
     4381 aacaagctat taaagaagtt cttagtatag tgaaaaacta taatcatgaa attacaatta
     4441 tagaatgtga taatgaaatt agacgtgtat ataaagtgag aactgaaaaa gatataaaag
     4501 atagaattag gataggtgga ggtactagat tttctccagt ctttgagtat gctaataata
     4561 aaaagattaa tttgttagtc tactttactg atggtaaagg tgaaaataaa ctacaagtaa
     4621 tacctagagg gtacaaaatt ttatgggtta tttctggaag aggagataaa atttcattaa
     4681 aagaacctta tggagcagtt aaaaaactta ctaaggttaa aacaaatgat gaaatattag
     4741 aaataaatga tgtaagaaat gatgggtact caatgaatag ccaagcacca attttatagg
     4801 tattcacagg agataagctg tattaattta ttttgatatg cttgttataa aaatctaaaa
     4861 aatacattaa tcaatggtta atgtattttt taattttaat aatataagtt ttacttacat
     4921 ttaagtctca aaatgtgtta aaatataata tatagcagat agttttggca aggtggattt
     4981 agttgtcaaa actatttttt ttattaagga tggtgatgtt tttgtttaag attgatgatt
     5041 atataatgta tggtatgaca ggagtctgca aagtcatgga tataacaaat gaacgattta
     5101 caaatggaat aaaaaaagag tattatgtat tgagtcctat ttattctaat aatacagtaa
     5161 taaaaattcc tgtagataat gaaaaagtac caatgagaaa gttactttct aaaattaatg
     5221 tgctttcatt aataaatgat attcctaata tggatacatc atggatagat aatgaaaaat
     5281 tgagaagtga gcaatttaaa aaaatactca gaggtggtaa atgtgaagag ttaataaaat
     5341 tagtaagaag tatagataat aacagagagt atgtaaaatc tattggtaaa aaaacacatc
     5401 aagcagatga taatataatg aaagaagctg aaaggttatt aaatgaagaa tttgcaacta
     5461 ttttagatat ttctcctaat gaagttagtt catatatttc aagtcatata cctcaataaa
     5521 gtgttttagt atcctttatt taatctattt taagtattat ttatgtatgc tggttttggt
     5581 aaaataaaat atataattaa attatataaa aaataataat gattgtattg aagaattaca
     5641 gaatagtgcg gagagcctac tcctttaggt gtgagatgga tatcacttaa agatttaaat
     5701 tgttattgta gatgttttta atataaaaca agattaataa gtgtattgta agctttaagt
     5761 gaaattgata ctataatgag ttacttagat tttaaaatat ataatattat aaaaaatcct
     5821 tttaggtttt gaatgaataa gatggatact atgttgaata gaatccatct tatttaagtt
     5881 ttatttatgt tgtttatttg taagcattat ttttgtacat gaaaacacag tgtaaaaata
     5941 tgcttagaat tatgaagttt tattaaaaag atattcgaca aaataagact aaaaatattc
     6001 ttaaacttat aactaagata aatattgtat atttatagtg tagcctgaaa aattgtggat
     6061 gtacgaaatt tatttagtat tttattgaaa caaagtagaa gaagtactat agtttatctt
     6121 tgaatagatt gttatttttt agtgaaaaag ttattaggtt aatacataaa tataatagct
     6181 tataaatagt ttaagcatgt taaaaaagta gttattagag atatatagtt acattgctta
     6241 taagatactt aaaatgatag cattcactta tattcagaag attaagat
//
LOCUS       DAYAOO010000155         6103 bp    DNA     linear   BCT 12-OCT-2024
DEFINITION  TPA_asm: Clostridioides difficile isolate ST8-SSI-h139-18
            SAMN40601845-rid21577343.denovo.159, whole genome shotgun sequence.
ACCESSION   DAYAOO010000155 DAYAOO010000000
VERSION     DAYAOO010000155.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN40601845
            Sequence Read Archive: SRR28438827
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 6103)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6103)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-MAY-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-MAY-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002157583.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002157583.1
            Genome Coverage       :: 163x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/11/2024 16:19:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 4,038
            CDSs (total)                      :: 3,963
            Genes (coding)                    :: 3,930
            CDSs (with protein)               :: 3,930
            Genes (RNA)                       :: 75
            rRNAs                             :: 6, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 60
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 33
            CDSs (without protein)            :: 33
            Pseudo Genes (ambiguous residues) :: 0 of 33
            Pseudo Genes (frameshifted)       :: 7 of 33
            Pseudo Genes (incomplete)         :: 25 of 33
            Pseudo Genes (internal stop)      :: 11 of 33
            Pseudo Genes (multiple problems)  :: 8 of 33
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6103
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN40601845-rid21577343.denovo.159"
                     /isolate="ST8-SSI-h139-18"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Denmark"
                     /collection_date="2018"
                     /collected_by="Statens Serum Institute"
     gene            complement(951..1502)
                     /locus_tag="ACGI5H_003776"
     CDS             complement(951..1502)
                     /locus_tag="ACGI5H_003776"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454500.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="XRE family transcriptional regulator"
                     /protein_id="HFG9699449.1"
                     /translation="MSINTVIAKNLNRLRNERNLSLGQLAELSGVSKVMLSQIEKGDS
                     NPTVNTIWKIASGLNVPYTAILEQPQNETFIVSKTDIDVQVSENKDYRLYCYYPNTPT
                     RNFELFQMELEEGHSYTSVGHSEKSQEYIMIIEGQLKLEVNDSIYQLRENDSICFSAE
                     SIHTYHNQGEKTLKAVIINYYPV"
     gene            1693..2655
                     /locus_tag="ACGI5H_003777"
     CDS             1693..2655
                     /locus_tag="ACGI5H_003777"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896810.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PLP-dependent cysteine synthase family protein"
                     /protein_id="HFG9699450.1"
                     /translation="MRVLNNVTEAIGNTHMLHLSKIADEFGVQGNIYAKMEYLNPGFS
                     KKDRVALQMITEAENAGLLVPGQAVVELTSGNTGTGLAIACACKGYKFIACMSKGNSM
                     ERARMMKALGAEVVLVDQMPNSVHGQVSGEDLALVEIEAQKIAKERNAFRADQFNLEA
                     CNHAHEKYTAEEMWEQLDGNIDVFVDFLGSGSTFAGCSKTLKKHNSSIKCYVVEPETA
                     AIYSGKEITDQGHKIQGGGYSMDLPLVDKKLIDGYIQVTDEEATDVARKLAKLEGVFA
                     GFSSGANVCAAIKLLKSSEKGKNIVLTLNDSGLKYLSTDLYEEL"
     gene            2950..4794
                     /locus_tag="ACGI5H_003778"
     CDS             2950..4794
                     /locus_tag="ACGI5H_003778"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerophosphoryl diester phosphodiesterase
                     membrane domain-containing protein"
                     /protein_id="HFG9699451.1"
                     /translation="MQKRILRNFIFTGKNILSKLVFIIKYNFSTLILFELFHKGLALF
                     FIWPSIRYIFDILIKSLHIVYLNMDNFIKVLTNPMSIVLIILSVIILAFYAFFEFTSV
                     IICFNKSIKYEKIGLFELFKISFKNSIKLLYPKNILLFIFVILIIPLVNTVLISGFIG
                     KIQIPEYILDYIKSDIILNIIYMIFLLIIYISVIRWIFSIHEITLNTENFKRARKESV
                     NLIKGKIIRTIIYSLILSLVVAIIGYAIYHSGIIFIGIWTKYCTDMEFLKNVFINRCI
                     AFEEYFRLILSIFIFILDIGFISATYYQYKGVNISKNNIKKEKKSISKIVFNLVLILL
                     ISYIESVAFSSHINGMFNTSFSFYTTAIAHRAGAEMAPENTLAAIEEASHAKADYAEI
                     DVQETKDGELIVLHDSNFKRTTGVDKNVWDVNYNEVKTYDAGSFYYYGKGYYDEKFVG
                     EKIPTLKEMIKYSKGKVKLLIEIKLNGHEKGDVVKKVVQLIKENNFENQCIVASMDKT
                     ILQKVKKLDENLLTCYFMAIAYGDFSKLNYVDIYGIESTFVNKTVVEKIHKMNKKIFV
                     WTVNSDSLIEKMLDLNVDSIITDNPYLIESAIYWKKNGFISQVSDYLF"
     gene            5116..5700
                     /locus_tag="ACGI5H_003779"
     CDS             5116..5700
                     /locus_tag="ACGI5H_003779"
                     /EC_number="2.3.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016407 - acetyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sugar O-acetyltransferase"
                     /protein_id="HFG9699452.1"
                     /translation="MTEREKMLAGELYDCGDIELLTQWHKAKGLVRDYNQTDSSDLEK
                     KEKILNELLGGKGKNLWITAPYYVDYGNNIYFGNNCEVNMNCTFLDDNKIIIGDNALI
                     APNVQIYTAFHPTNAGDRFGNAKEDGSFEFCKTQTAPVTIGDNVWIGGGAIIMPGVTI
                     GDNVVIGAGSIVTKDIPSNMIAYGNPCRIIRENK"
BASE COUNT         2386 a          594 c          931 g         2192 t
ORIGIN      
        1 ttgaaaataa aaattaaaaa atatttaatg ctactacaat aggaactaga actacactta
       61 ataaatatac agaaattaga tttggctcaa tataaaatac aaatatagaa tttaggtgtt
      121 ttttatgaaa aaatttttat atgctttata tagtttcatt gttattatag ctaattttag
      181 attaaaagaa aaaaattata actttatttt attagcaatc ttttttatat tgctgttaat
      241 tcaaaatgga gttttaaaaa caggttatca aaatagagct acattttatc aagataatta
      301 ttttaataga gaggataaaa atgataagat aaaatttatg actataaaga tttttatatt
      361 tttgtcatta ccattatgtt ttaatatact attcaattat ttaacctctt aaattatatt
      421 tagatatagg agtcttatga taaaagtaag cttatgtgtt atttgtagta aatataaagt
      481 gcatatagtg ataaaacaaa agtttcatat aaatgaagaa aaaaatataa aataatttat
      541 ttaactactt aaaaataaac taaaagggat aataaaatag cttttaggtt atggtaataa
      601 aggtatttaa aaagagtgca taagcactcc aattgtgaga aatacataca caaatcatta
      661 ttacaacaat gaaaaatgta catataagag acgttttgta tttgttttaa gtgataatat
      721 tttaatacta actaaataat tatcacaata gtaaaaaaga aaaaggagta ttttgtactc
      781 catttgtcaa aaatataaaa cttttatata agcttattat aacataattg ataaaagtgt
      841 aaagatatat aatgaattta taaagaaaaa taaaataaaa aagataaatc ctaatcaaag
      901 gatttatctt tttgtataga aaataattat tctattatta aatggcatgg ctaaactgga
      961 taataattta ttattactgc tttcaatgtt ttttctcctt gattatggta tgtatgaatt
     1021 gattcagctg aaaaacaaat agagtcattt tctctaagtt gataaataga gtcatttact
     1081 tctaatttta attgaccttc tataatcata atatattcct gtgatttttc agaatgacca
     1141 acagatgtat aactatgacc ttcttctaat tccatttgaa ataattcgaa gtttctagtt
     1201 ggtgtattgg gataataaca ataaagacga taatctttat tttctgaaac ttgtacatct
     1261 atatcagttt ttgatacaat aaaagtttca ttttgaggtt gttccagtat tgcagtatat
     1321 ggaacattta gtccacttgc aattttccaa attgtgttta ctgttgggtt tgagtctccc
     1381 ttttcaattt gcgaaagcat tactttactt acgccagata attcagcaag ttgacctaga
     1441 cttaagttac gttcattacg taatctattt aaatttttag caataacagt attaatactc
     1501 atagtagctc cttaaaatgt aaattattga caaatataat ttacgaatgt ataatttatt
     1561 taacattatt tataatttac aaatgtataa tataatgaac gttaaataca ctgtacatcc
     1621 gtaatataaa ttatactgca taaagagttg tttttcaacg gatgatagtt gagagattaa
     1681 gggggaattg taatgcgtgt acttaataat gttacagagg ctataggcaa tactcatatg
     1741 ttacatttat ccaaaatagc agatgaattt ggagttcaag gtaatattta tgcaaagatg
     1801 gaatacttaa atccgggatt tagtaaaaag gaccgtgtag cattacaaat gattaccgaa
     1861 gcagaaaatg caggtttatt agttccaggt caagcagttg tggaattaac aagtggtaat
     1921 actggaacag gactagcaat agcttgtgca tgtaaaggat ataaatttat agcgtgtatg
     1981 tcaaaaggaa attctatgga aagagcaaga atgatgaaag ctttaggtgc tgaagtagtt
     2041 cttgtagacc aaatgcctaa ttcagttcat ggacaggtat ctggtgaaga tttggcactt
     2101 gtagaaattg aggctcaaaa aatagcaaaa gaaagaaatg catttagagc agaccaattt
     2161 aatttagaag cttgtaatca tgcacatgaa aagtatacag cagaagaaat gtgggaacaa
     2221 ttggatggaa atattgatgt atttgtagat tttcttggaa gtggtagtac ttttgcagga
     2281 tgttcaaaaa cacttaaaaa acataattct tctatcaaat gttatgttgt tgaacctgaa
     2341 acagcagcaa tttattcagg taaagaaata actgaccaag ggcataaaat acaaggtgga
     2401 ggatattcta tggatttgcc attagtagac aagaaactta ttgatggtta tattcaagtt
     2461 acagacgagg aggcaactga tgtagcaaga aaattagcta aattagaagg tgtatttgca
     2521 ggattttctt caggggcaaa tgtatgtgca gcaattaagt tgttaaagag cagtgaaaaa
     2581 ggaaaaaata tagttttaac tcttaatgat agtggtttaa aatatttaag tactgattta
     2641 tatgaagaat tgtaataata gcacaatagt tatgcaatgt tttttaaatt aagtatatag
     2701 atttaaatta taaaaagtat ctcaatgtaa tttttgaaag ttataaagga gatacttttt
     2761 tattttgtaa atatggagta tcctacttat aagtattaag ctatatagat attgatgatt
     2821 agctatgcaa taaaaaagag tatgtgtttt tgcatttata catcataact tggaataata
     2881 catattaatg ttctaaatgt atttaaaaca tatgataaaa ttagaacaaa tagatacaag
     2941 gagataaaaa tgcaaaagag aattttaaga aattttatat ttacgggtaa aaatatttta
     3001 agtaaacttg tttttataat aaaatataat tttagtacat taattttatt tgaattattt
     3061 cataaaggat tagccttatt ttttatatgg ccatctatta gatatatatt tgatatttta
     3121 ataaaaagtt tacatatagt ctacctaaat atggataatt ttataaaagt tttgaccaat
     3181 cccatgtcaa tagttctgat aatactatca gttataatac tagcttttta tgcatttttt
     3241 gaatttacct ctgtaattat ttgttttaat aaatcgataa aatatgaaaa aatagggtta
     3301 tttgaactct ttaaaatatc atttaagaac tctataaaat tgttatatcc taaaaatata
     3361 ctattattta tatttgtgat attaataatt ccattagtaa atacagtttt aatttcaggg
     3421 tttataggaa aaatacaaat accagagtac atactagatt atataaagtc tgatataatt
     3481 ttaaatataa tctatatgat ttttctttta ataatatata tttcggttat tagatggatt
     3541 tttagcattc atgagataac tttaaataca gaaaatttta aaagagcaag aaaagaaagt
     3601 gttaatctta taaagggaaa gattataaga acaattattt attcattaat attatcttta
     3661 gtagtagcta ttattggata tgcgatttat catagtggaa ttatatttat aggcatatgg
     3721 actaaatatt gtactgatat ggaatttttg aagaatgtat ttataaatag atgtattgca
     3781 tttgaagaat attttagatt gattttatca atattcattt ttatattgga cattggattt
     3841 atctcagcaa cttattatca atataaagga gtaaatattt ctaaaaataa tattaaaaaa
     3901 gagaaaaaat ctatatcaaa aattgttttt aatttagtat taatattatt gatttcttat
     3961 atagagtcag ttgcattttc ttcacatata aatggtatgt ttaatacgtc attttcattt
     4021 tatacaacag caattgctca tagagcagga gctgaaatgg ctccagagaa tactttggca
     4081 gcaatagaag aagcttcaca tgctaaagct gattatgcag aaatagatgt tcaagaaact
     4141 aaagatggag aacttattgt acttcatgat tcaaacttta agagaactac aggagtagat
     4201 aaaaatgttt gggatgtaaa ttataatgaa gtaaagacat atgatgcggg aagcttttat
     4261 tattatggaa aaggttatta tgatgaaaag tttgttgggg aaaagatacc aacactcaaa
     4321 gaaatgataa aatattctaa aggtaaggtg aaattattaa tagaaataaa acttaatgga
     4381 catgaaaagg gagacgtagt aaaaaaagtt gttcagttaa ttaaagaaaa taattttgaa
     4441 aatcaatgta tagttgcatc tatggataaa actatattac aaaaagtaaa aaaactggat
     4501 gagaatttat tgacatgcta ttttatggca attgcatatg gtgatttttc aaagttaaat
     4561 tatgttgata tatatggaat tgaatcaact tttgttaata aaacagtagt agaaaagatt
     4621 cataaaatga acaaaaaaat cttcgtttgg actgttaata gtgacagttt aattgagaaa
     4681 atgcttgacc taaatgtaga tagtattatt acagataatc cataccttat agagagtgca
     4741 atttattgga agaaaaatgg atttattagt caagtgtcag attatttatt ttaaatattc
     4801 tataattgta ttatccagta aaagagatat tattaaaatc aataatatct ctttttaaca
     4861 taaataaggt tgttaaatta aggttattct tataaaaatt gtgcttatca gctataaaca
     4921 aggaataaaa gtgaaaaaat tgctctgaga ttattacagt taaaagagtt ttaagatgac
     4981 agagagatag attgtcaact gtatatttaa taaatcttgt tatttattaa attttatata
     5041 agtaaaatat ataaattaat aaatcttatg ctagaatata tatgaaaaac aatataaatt
     5101 tggaggatta aaaacatgac agagcgagaa aaaatgttgg caggagaact ttacgattgt
     5161 ggtgatattg agttgttaac tcaatggcat aaagcaaaag gcctagtaag agattataac
     5221 caaacagatt cctcggattt ggaaaaaaaa gaaaaaatat taaatgagtt acttggtggt
     5281 aagggtaaaa acttatggat tactgcaccg tattatgtag attatggaaa taatatttat
     5341 tttggaaata attgtgaagt caatatgaat tgtacgtttt tagatgataa taaaattatc
     5401 attggggata atgcactaat cgcaccaaac gtacaaatat atactgcatt tcatccaact
     5461 aatgctggtg atagatttgg taatgccaaa gaagatggtt catttgaatt ttgtaaaact
     5521 caaacagctc cagttactat tggagataat gtttggattg gcgggggtgc tattatcatg
     5581 ccaggtgtta ctattggaga taatgtagtt ataggtgcag gaagtattgt tacaaaagat
     5641 attccaagta atatgattgc atacggaaat ccatgccgta ttattcgaga aaataaataa
     5701 agttaaattt tcttgcaaaa tctcaaaaaa cacctttctt actttataca tagggtattt
     5761 tctaatactt tcacatccat attcatttgt taaatttttg tggaatgtag tttttatcac
     5821 ttctatctta catttccacc atttttttat aaaagtcatt cctttataga tttatttata
     5881 atagtatata ttctatttga tgtttgaata agcacttatt tttaagtaaa atactaactt
     5941 ttaggttagt attttgctat agtatgatga ttaagtaaga ataaaatact ataatacata
     6001 aagcttaata aatataattt ttattttact tagatatttt cttttgatta gcaatcaaaa
     6061 gtagttataa tttttttaat taataagagt aacatttatt tta
//
LOCUS       DAYAOO010000156         5667 bp    DNA     linear   BCT 12-OCT-2024
DEFINITION  TPA_asm: Clostridioides difficile isolate ST8-SSI-h139-18
            SAMN40601845-rid21577343.denovo.160, whole genome shotgun sequence.
ACCESSION   DAYAOO010000156 DAYAOO010000000
VERSION     DAYAOO010000156.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN40601845
            Sequence Read Archive: SRR28438827
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 5667)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5667)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-MAY-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-MAY-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002157583.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002157583.1
            Genome Coverage       :: 163x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/11/2024 16:19:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 4,038
            CDSs (total)                      :: 3,963
            Genes (coding)                    :: 3,930
            CDSs (with protein)               :: 3,930
            Genes (RNA)                       :: 75
            rRNAs                             :: 6, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 60
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 33
            CDSs (without protein)            :: 33
            Pseudo Genes (ambiguous residues) :: 0 of 33
            Pseudo Genes (frameshifted)       :: 7 of 33
            Pseudo Genes (incomplete)         :: 25 of 33
            Pseudo Genes (internal stop)      :: 11 of 33
            Pseudo Genes (multiple problems)  :: 8 of 33
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5667
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN40601845-rid21577343.denovo.160"
                     /isolate="ST8-SSI-h139-18"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Denmark"
                     /collection_date="2018"
                     /collected_by="Statens Serum Institute"
     gene            303..1574
                     /gene="serS"
                     /locus_tag="ACGI5H_003780"
     CDS             303..1574
                     /gene="serS"
                     /locus_tag="ACGI5H_003780"
                     /EC_number="6.1.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006441208.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0004828 - serine-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006434 - seryl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="serine--tRNA ligase"
                     /protein_id="HFG9699453.1"
                     /translation="MLDIKRIRENLDCIKKAMERRGEKDFNLDEVVKLDDERRKILQE
                     VEVMKNELNTASKNIPNLIKEGKDVENEKIKLKELSDKIKVIDQNLKEVEDKMEYLLM
                     RIPNVPHPEVPQGETDEDNVEVRTWGKTTTFDFESKAHWEIGTELGILDFETASKITG
                     SRFTLYKGLGARLERALLNFYLDTNTKVNGYTEVIPPFMANRNSFLGTGQLPKFEEDM
                     FKIEGMDYFMIPTSEVPLTNIHANEILKFEQLPINYTAYTPCFRSEAGSAGRDTRGLV
                     RQHQFNKVEMVKIVAPEESYNELEKLTNNAETMLQLLNLPYRVVKICTGDLGFTASFK
                     YDVEVWMPSYNRYVEISSCSNCEDFQARRAGIRFKRDKDSKAEYVHTLNGSGLAIGRS
                     VAAILENYQQEDGSVVVPEVLRPYMGVSVIK"
     gene            1852..3357
                     /locus_tag="ACGI5H_003781"
     CDS             1852..3357
                     /locus_tag="ACGI5H_003781"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422776.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0000155 - phosphorelay sensor kinase
                     activity [Evidence IEA];
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="histidine kinase"
                     /protein_id="HFG9699454.1"
                     /translation="MKIQNTEWGYIEWKHTYDENNPKQAMNIYIAVTMPGKKHFNHVH
                     YGQEQMIYILEGEGLYIINGVWKPFYQGMIFYIESGSTHETINTGDREIKELIVSNNV
                     DDVGESEVIDINPNNYLKKTLINYSESTLNLYAAVESIRGQFIDPFKIPLIIYDDSWN
                     IVLKNPYFPLFCFEKCNPMKFPQNCDCMNQKSSNQFVCEYGITIYNIPILYKSNSIGV
                     IRGGYVLLSDLNLDTEHNNLYDIPEGAARSIKRLLKQISKNIINFCSFNDIRKDLQEK
                     EKTIARTYHYGEQLEMNLKVAQDMVTNLRINHHFLFNTLNSMASIALDDGSYDLYSAI
                     IDLSRMFRYTMRSDLRFVELESEILYIKNYLNLQKLRYGDALKVKYLIPEKLYNLSVP
                     FNFIQPIVENAFTHGFRDIDTEKRIEIIARLDSQYAIIEIHNNGTILDGNNIDKIKAG
                     IRSNNGHGLSLIYTKFTSAYGNNFDMDIKSSDNEGTYIMIKIPIENYKEYV"
     gene            3471..4169
                     /locus_tag="ACGI5H_003782"
     CDS             3471..4169
                     /locus_tag="ACGI5H_003782"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436119.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator"
                     /protein_id="HFG9699455.1"
                     /translation="MRRALIIDDEEAVLKIITHFIEMKDMPIKIVGKATSGDEAVDKI
                     IGLEPDIVFIDIQMPIYNGLEVIEKTSHLSKKINFVVITAFNYFEYAQKALRLNVKDI
                     LLKPLDMKEFTKSVEKIIGYQYTNNDLLNEILEYINLNYSNDLKLNDCARLFLTNPSN
                     ISRIFKSNLNTTFISYLNHIRIEKSIELLENTTKSINEIAEIVGYNSLNNFYKNFKIE
                     KGMTPKVYKLNTKN"
     gene            4454..5542
                     /locus_tag="ACGI5H_003783"
     CDS             4454..5542
                     /locus_tag="ACGI5H_003783"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436120.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9699456.1"
                     /translation="MSDKVNMKNIICIAGAYLATAIGSGFATGQEILQFFASQGYMGL
                     IGALISMVLFSFLGAEVITRGRELKLKEPTRIYTFYCGKILGKFYEWFSPIFLFGILI
                     VMISGAGSTLTEYYGINPYLGRVLMAVATLITVSMGLEKLVSILGRIGPVIAVFTIAV
                     GLISLFKHFDGLSMVGEAMKNIEVTKASESPIVSGVIYNTLNIIVMIVFLTGMGASIE
                     SKKDAFWGGLLGGIVFMTAGIVMYLAMISDIGNLYMKEIPSLYLADNISPIVGVCFSV
                     ALILGIYTTAVPLLWSVTNRIVEDEHPKFKLVTTVIAILACIGGFLPFGKLVNILYPY
                     TGYMGLLILVCMVYKAITCRKKSTQSQE"
BASE COUNT         2294 a          559 c          942 g         1872 t
ORIGIN      
        1 atttatataa aagttaataa ctatacaaga ttgataaaga aaaagtcaaa atagataatt
       61 gattagcaaa atagatataa ttataatgaa gttaaatcta gcaatattct cctaaaatta
      121 aattacattt atttaattaa atataatttg acaatggaca aaaaagtgag taaaatataa
      181 ataaaataaa aataacaggt tcggataaag aaaaaggttt cttaacctca agcataaagt
      241 atattatcta agttatttga gattaagaga taaatccaat cttaggtact gaggaggaaa
      301 aaatgcttga tataaaaaga ataagagaaa atttagattg tataaaaaaa gcaatggaaa
      361 gaaggggcga aaaagacttt aaccttgatg aagtagttaa gttagatgat gaaagaagaa
      421 agattcttca agaagttgaa gttatgaaaa atgaattaaa tacagcatct aaaaatatac
      481 caaatcttat aaaagaaggt aaagatgtag aaaatgaaaa gattaaacta aaagagttat
      541 ctgataaaat taaggtaata gaccaaaatc ttaaagaagt agaagataag atggaatacc
      601 tattaatgag aataccaaat gtaccacatc cagaagtacc acaaggtgaa actgatgaag
      661 ataatgttga agtaagaact tggggaaaga ctactacctt tgattttgaa tctaaggctc
      721 attgggaaat tggaacagaa ttaggtatac ttgattttga aacagctagt aaaataactg
      781 gttcaagatt tactctttac aaaggattag gtgctagatt agagagagca ttattaaatt
      841 tttacttaga cacgaataca aaagtaaatg gatatacaga agttattcca ccatttatgg
      901 caaatagaaa tagtttttta ggtacaggac agttacctaa gtttgaagaa gatatgttta
      961 aaatagaagg tatggactat tttatgattc caacatcaga agttccttta actaatatac
     1021 atgctaatga aatacttaaa tttgaacaat taccgataaa ttatacagct tatactccat
     1081 gttttaggtc agaagctggt tctgctggaa gagatacaag aggtttagta agacaacatc
     1141 agtttaacaa agtagaaatg gttaaaatag ttgcaccaga agaatcttac aatgagttag
     1201 aaaagcttac taacaatgcg gaaactatgc tacaattatt gaatctgcct tatagggtag
     1261 taaagatatg tacaggtgat ttaggattta cggcttcttt taaatatgat gtagaagttt
     1321 ggatgccaag ttacaatagg tatgttgaga tttcatcttg ttcaaactgc gaagatttcc
     1381 aagctagaag agcaggaata agatttaaaa gagataaaga ttctaaagct gaatatgtac
     1441 acacattaaa tggctctggg ttagctattg gaagaagtgt tgcagctata ttagaaaatt
     1501 atcaacaaga agatggttct gtggttgttc ctgaagtttt aagaccatat atgggagttt
     1561 ctgttattaa gtaagagtta aattatgtat ttttaagcaa tacaataata tagaggtaat
     1621 aaaaaataat taatataaaa gtgatacaat aatatagaag taataaaaaa atagttaata
     1681 taaaagtgat acaataatat agaagtaata aaaaaaaata attaatataa aaatgtgtac
     1741 aaactaatga atattgatat agtaagctat catatgaaag agtatgtaca catttttttt
     1801 actaattttt cacaatatga acataaataa tttacaggaa aggaatcttt tatgaaaatt
     1861 caaaatactg agtggggata tattgaatgg aaacatactt atgatgaaaa taatccaaaa
     1921 caagctatga atatatacat tgcagtaact atgcctggta agaaacattt taatcatgtt
     1981 cattatggtc aagagcagat gatatatatt ttagagggag agggtttgta tattataaat
     2041 ggagtttgga agccatttta tcaaggtatg attttttata tagaatctgg tagcacacat
     2101 gaaactataa atacaggtga tagagaaata aaagaactta ttgtttcaaa taatgtagat
     2161 gatgtaggag agagtgaagt tatagatatt aatcctaata attatttaaa gaagaccttg
     2221 ataaattata gtgaaagtac attaaatttg tatgcagcag tagaatcaat tcgtggtcaa
     2281 tttatagacc cgtttaaaat tccattaatt atatatgatg attcatggaa tatagtttta
     2341 aaaaatcctt attttccact tttttgtttt gaaaaatgta atcctatgaa atttcctcaa
     2401 aattgtgatt gtatgaatca aaaaagtagc aatcaatttg tatgtgaata tgggataact
     2461 atatataata taccaatact gtacaaaagc aatagcatag gtgttataag aggagggtat
     2521 gtactattat ctgatttgaa tttagataca gagcataata atttatatga tattccagag
     2581 ggagctgcta gaagtataaa acgcctcttg aaacaaatat ctaaaaatat aataaatttt
     2641 tgctctttta atgatataag aaaggattta caagaaaaag agaagactat agcaagaaca
     2701 tatcattatg gagagcaact tgaaatgaat ttaaaagtag ctcaagatat ggttactaat
     2761 ttaagaataa atcatcactt tttatttaat acattaaatt caatggcaag catagcacta
     2821 gatgatggta gttatgattt gtatagtgca ataatagatt tatcaagaat gtttagatat
     2881 acaatgaggt ctgatttaag atttgtagaa ttagaatctg aaatattata cattaaaaat
     2941 tatttgaatt tacagaaatt acgttatgga gatgcactta aagtaaaata tcttattcca
     3001 gagaagttat ataacctttc tgtgcctttt aactttattc aacctattgt agagaatgca
     3061 tttacacatg gatttagaga tattgacaca gaaaagcgaa ttgaaataat tgcaagatta
     3121 gattctcagt atgctattat agagattcat aataatggaa ctatcttaga tggaaataat
     3181 atagacaaaa taaaggcagg tattcgtagt aataatggtc atggtttgtc tttaatatat
     3241 acaaaattca catctgctta tggaaataat tttgatatgg atataaagtc gagtgataat
     3301 gaaggaactt acataatgat taaaattcct attgaaaatt ataaggagta tgtatagaac
     3361 ttgtgaaaaa ttaataagtt ttataaatgt taagaaatat attagatgtt tttatgttgt
     3421 tttatatatc ttactttttt atattattaa gctaaaaggg aggtattctc atgagaagag
     3481 cactaataat agatgatgaa gaagctgttc taaaaataat aacacatttt atagaaatga
     3541 aagatatgcc aataaaaatt gttggtaaag caacatctgg tgatgaagca gtagataaaa
     3601 tcattggttt agagccagac atagttttta tagatattca aatgccaata tacaacgggt
     3661 tagaagtaat agaaaaaaca tctcatttat ctaaaaaaat aaactttgta gtaataactg
     3721 catttaacta ttttgaatat gctcaaaaag ctttgagatt aaatgtaaaa gatatactcc
     3781 ttaaaccatt ggatatgaaa gaatttacta agtctgtaga aaaaattatt ggatatcaat
     3841 ataccaataa tgatttatta aatgagatac tggaatatat aaatctaaac tatagcaatg
     3901 acttaaagtt aaatgattgt gctagattat ttttaaccaa tccatctaat atatctagga
     3961 tttttaaaag taatttaaat acaactttta tatcatatct aaatcatata agaatagaaa
     4021 aatctattga gttacttgaa aatactacaa aaagtataaa tgagattgca gaaatagttg
     4081 gatataatag cctaaataac ttttataaaa actttaagat agaaaaagga atgactccaa
     4141 aagtttataa actgaacact aaaaattgaa attgataaat aaaaagtcaa tatagataat
     4201 tgtttgagtg tgtctgaata agtatacttt aattatgata aaaattaaag cgctttaaac
     4261 atatttaata atattaaacc ttataaaagc tgtacctatt tatataaaaa aatatatata
     4321 aataaaaaga aaaagatata caaaataaaa aaagtgaatt aaatactgtt tcaaaaagac
     4381 agaattttca tttaatttac tgagagttta tatttcttaa aggaaggtaa ctttataatg
     4441 gaggtaattt aatatgtcag acaaagtgaa tatgaaaaat attatctgta ttgcaggcgc
     4501 ttatctagca acagcaattg gttctgggtt tgctactggt caagaaattc tacaattttt
     4561 tgcctcacaa gggtatatgg gtttaattgg agcattaata tcaatggtat tgttttcatt
     4621 tcttggtgct gaagttataa ctagaggtag agaattaaaa cttaaagaac caacaagaat
     4681 ttacactttt tattgtggga agattttagg aaaattttac gaatggttta gtccaatatt
     4741 tttatttggg attcttatag taatgatttc aggtgcaggc tcaactttaa ctgaatacta
     4801 tggtataaat ccttacttag gaagagtatt gatggctgtt gctactttaa ttacagtgtc
     4861 tatgggttta gaaaaattag taagcatact tggacgtatt ggaccagtga tagcagtatt
     4921 tacaattgct gttggattaa taagcttgtt taagcatttt gatggtttat ctatggttgg
     4981 agaagctatg aaaaatattg aagttacaaa agcatcagaa agtccaatcg tttctggtgt
     5041 aatatataat acattaaata ttattgtaat gattgttttt ttaacaggaa tgggagcttc
     5101 tattgaaagt aaaaaggatg ctttttgggg aggtttatta ggtggaatag tgtttatgac
     5161 tgctggtata gttatgtatt tggctatgat ttcagatata ggaaatttgt atatgaaaga
     5221 aataccatca ctttatttag cagataatat atctcctatt gtaggtgtat gtttttcagt
     5281 tgcattaata ttaggtatct acacaacagc tgttccactt ttatggtctg taaccaatag
     5341 aattgttgaa gatgaacatc ctaaatttaa attggtaaca acagtaatag ctattttggc
     5401 ttgtatagga ggttttttac cgtttggtaa actagtaaac attttatatc catatacagg
     5461 ttatatgggg cttttaattt tagtctgtat ggtgtataaa gcaattacat gtagaaaaaa
     5521 atcaacacaa agtcaggaat agagccactt attaatagtt tttatttaaa gaaatttttt
     5581 atataatccg aatttaaaaa gtcaaaatag ttaaataaat tgtaaaatat gataatatat
     5641 ttaattaaaa taatatagta aaatata
//
LOCUS       DAYAOO010000157         5656 bp    DNA     linear   BCT 12-OCT-2024
DEFINITION  TPA_asm: Clostridioides difficile isolate ST8-SSI-h139-18
            SAMN40601845-rid21577343.denovo.161, whole genome shotgun sequence.
ACCESSION   DAYAOO010000157 DAYAOO010000000
VERSION     DAYAOO010000157.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN40601845
            Sequence Read Archive: SRR28438827
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 5656)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5656)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-MAY-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-MAY-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002157583.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002157583.1
            Genome Coverage       :: 163x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/11/2024 16:19:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 4,038
            CDSs (total)                      :: 3,963
            Genes (coding)                    :: 3,930
            CDSs (with protein)               :: 3,930
            Genes (RNA)                       :: 75
            rRNAs                             :: 6, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 60
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 33
            CDSs (without protein)            :: 33
            Pseudo Genes (ambiguous residues) :: 0 of 33
            Pseudo Genes (frameshifted)       :: 7 of 33
            Pseudo Genes (incomplete)         :: 25 of 33
            Pseudo Genes (internal stop)      :: 11 of 33
            Pseudo Genes (multiple problems)  :: 8 of 33
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5656
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN40601845-rid21577343.denovo.161"
                     /isolate="ST8-SSI-h139-18"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Denmark"
                     /collection_date="2018"
                     /collected_by="Statens Serum Institute"
     gene            192..374
                     /locus_tag="ACGI5H_003784"
     CDS             192..374
                     /locus_tag="ACGI5H_003784"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9699457.1"
                     /translation="MFKDKIDECVHIMTAYIASLKEYYSFIETQIGDFIKKYGEDVVE
                     LCLHRVMILLCECGLA"
     gene            1201..2115
                     /locus_tag="ACGI5H_003785"
     CDS             1201..2115
                     /locus_tag="ACGI5H_003785"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420014.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2935 domain-containing protein"
                     /protein_id="HFG9699458.1"
                     /translation="MIDNQKYVILSLELHLFFSRIMKEHALFLEAGFTNKNYNLAMEA
                     DHYKKQFEDLLSYTVSASNGIIRPDILYSEELVTTLTSVAEQKTEEFTGIEINKNITT
                     RELNLQSGVNPQVGQDLVNYVAQLNSDAIRLLDGLINFKERVLDGVLSCTIFTSNYPL
                     LLEHIIHEANLYRSYVVDLENKIDIESKNAKEIELFWDHIMMEHALFMRGLLDPSEGE
                     LINTSNDFAIKFNELIEKTNEMTDSNIKNITEETLNETVEFKDFKEAGASGIEQCKIK
                     SIILPLLADHVLREANHYIRILESYKNM"
     gene            2505..3152
                     /locus_tag="ACGI5H_003786"
     CDS             2505..3152
                     /locus_tag="ACGI5H_003786"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889349.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lactate utilization protein"
                     /protein_id="HFG9699459.1"
                     /translation="MIRQTPLEKRYDKLGPHIVTALKKRYFDAYYCKTRNEALQQILD
                     LIPQNHVVSWGGSETLKEMGVQTAVREKGFKVIDRDLAKTPEERTEIMRQALLCDTFL
                     MSSNAISEDGQLFNIDGNGNRVAAMIFGPKNVIVVAGMNKIVKNIDDAIQRTRTIASP
                     AVVQRFQDVNTPCYINGSCIDCTSPESICAYMVTTRISRPAKKIKVILVGENLGL"
     gene            complement(3319..3888)
                     /locus_tag="ACGI5H_003787"
     CDS             complement(3319..3888)
                     /locus_tag="ACGI5H_003787"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896453.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9699460.1"
                     /translation="MKKFILCIIMFAISVLVLAGCTNDNKIKNEVDSMFNSIKTQDAD
                     TVDKYFPKSGLGNLIYEDKEGFKMYSKNMTWEISDIKNNKDKVTVDLKINNTDMVSIL
                     KKNPPKLGEMMPNPTMKDIDSAKKKEFNITLELVKSGDNYVCKVNQESAMKLLNVITG
                     GGIDYLADYNKDYYKQLDEEQKNYENKNS"
     gene            complement(3893..4792)
                     /locus_tag="ACGI5H_003788"
     CDS             complement(3893..4792)
                     /locus_tag="ACGI5H_003788"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893092.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4Fe-4S binding protein"
                     /protein_id="HFG9699461.1"
                     /translation="MKLLSKVNNNIRLITQVAFTALTNGYVNGFLEGTIYGGESKKLC
                     VPGLNCYSCPGALGACPIGSLQAVLSSREYKFSFYVVGFLMAFGAFFGRFVCGWLCPF
                     GLVQDLLHKVPFPVKIKKVYGDKYLKYLKYIVLIIFVIILPVAIVNVAGGGNPWFCKW
                     ICPSGTLLGGIPLILGNENLRESIGFLFSWKLSILLLILLMSIITYRPFCKYICPLGA
                     IYGFFNPISIYRFKIDKDKCTNCTACQTKCKLDIPIYKDVNSPDCIRCGECIKVCPQN
                     AITTTFSKDKKENNICAKKYRGI"
     gene            complement(4803..4952)
                     /locus_tag="ACGI5H_003789"
     CDS             complement(4803..4952)
                     /locus_tag="ACGI5H_003789"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889347.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CD1871A family CXXC motif-containing protein"
                     /protein_id="HFG9699462.1"
                     /translation="MSNFIKDNKKGISIIAISIIFIALGTYRGETNTVLTKAIMICLE
                     CIGIG"
     gene            complement(4945..5529)
                     /locus_tag="ACGI5H_003790"
     CDS             complement(4945..5529)
                     /locus_tag="ACGI5H_003790"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TlpA family protein disulfide reductase"
                     /protein_id="HFG9699463.1"
                     /translation="MKRFFIVVLGCICVLGMISGCSKKESKPVEKNKNNSEWFSNLDT
                     EDVDGNKVTKEIFSNKELTLINVWTTWCGPCVGEMPELEALSKEYESNNSNVAIKGLV
                     VEVDKTDMRTGLSNEEKNLVKDIMKKSDATYQQLTVSEELKKTDFKRVMEFPTTYFVD
                     KKGNFVGEKVVGANSKEDWKKIIDERLKMVKANE"
BASE COUNT         2069 a          851 c          661 g         2075 t
ORIGIN      
        1 taaactttaa actggataaa ttttctttta agaatgaaag tttatccagt tttgcgatta
       61 taataaccag ttttacatat ccacttgtaa aatatatcta agcaatatat catactatat
      121 agatttatga gtgaaataat atctgctatt tactgaatat ttttattttt cgttttttag
      181 ggggattagt tgtgtttaaa gataagattg atgaatgtgt tcatataatg actgcatata
      241 ttgctagttt aaaagaatac tattcattca tagaaactca aattggtgat tttattaaaa
      301 aatatggaga agatgttgta gagttatgtc tccatagagt gatgattcta ctatgcgaat
      361 gtggtttggc ataaaattaa atttattaaa atgggtaaga agaatcctat ataatattct
      421 tcttacccat tttaatatat caatttcata gcttatcgtt taaaatattt tacatccatt
      481 actagacaac tttacattct ctttttaatt ctagtatatt taaatcattt tagttgctcc
      541 ttatttattc ttattacttg ttttatttat aaaataattc tttttaataa tgttttttgt
      601 tgatattcct atcacacatc caattattta tcattgtctt gaaattgttt gcatacttaa
      661 tttaatccaa ttgaaacacc ccagcataga atcccctgta aaatagaagt tggattaaat
      721 cctaacatct atacagaaaa tactactcca agcacaagca atataatgga atatatttat
      781 cacttaattt tttatacttt ttaaatccca tacctaaaac attaagtgca gctattagaa
      841 ttaataattg ttgtggtata aaattatgct tgcttcatat ttattcattt tttgctataa
      901 aagttcttgt tttacaaaaa acatttgttt tgtatcaaaa taatacttat aaattacata
      961 attctcataa aaatttctag tattacttgt actcttaata aataatagcc aacaagtacc
     1021 ttaaatcatt atatctatat ctaataagaa acacagtaag ataatctttt cgcccataac
     1081 ttaataaaaa ctgttgatat tagtagcaat tgaatttagt taatttattt ataatataca
     1141 taaatttaaa tattacgaat aaagtattat aaataggata ctttctaagg ggaggaaatt
     1201 atgatagata atcaaaaata tgttatttta tcactagaat tacatttatt tttttcaaga
     1261 attatgaaag agcatgctct ttttttagaa gcaggattca caaataaaaa ttataatctt
     1321 gctatggaag ctgaccacta taaaaagcaa tttgaagatt tattatcata cactgttagt
     1381 gctagtaatg gtataattag acctgatata ttatattcag aagagcttgt aactactctc
     1441 acatcagttg cagaacaaaa aacagaagag tttacaggga tagaaataaa caaaaacatc
     1501 actacaagag aattaaatct acaaagtggt gtaaacccac aagttggtca agacttagtg
     1561 aactatgtag ctcaacttaa ctctgatgca ataagattac ttgatgggct tattaatttt
     1621 aaagaaagag tcttagatgg tgtactatca tgtactatat ttacatcaaa ctaccctcta
     1681 cttcttgaac atataataca tgaagcaaat ttatatcgtt cttatgtagt tgaccttgaa
     1741 aataaaatag atattgagtc aaaaaacgct aaagaaatag aattattctg ggaccatatt
     1801 atgatggaac atgctctgtt tatgagagga ttactagacc cctcagaagg tgaactaata
     1861 aatacttcaa atgattttgc tataaaattt aatgaattaa ttgaaaaaac aaacgaaatg
     1921 actgattcta atatcaagaa cattacagaa gaaactctaa atgaaactgt tgagtttaaa
     1981 gattttaaag aagcaggagc atcaggaata gaacagtgta agataaaatc tataatatta
     2041 ccacttttag cagaccatgt tttaagagag gcaaatcatt atattagaat attggagagt
     2101 tataaaaaca tgtaattaaa aattactttt aaaataatct ttgcatattt agataaaata
     2161 aaggtacagt taactgtacc tttatttttt ataaacttat aaaatttaaa caagttattc
     2221 ataaaataaa ataataatca tctataaccc acaactttat tttatattaa ataaaaagta
     2281 ttagtggtta tgttttataa gtatttcttt attcagttat ttattaaaaa ctaatagtaa
     2341 atcttatact aatcgcatat ttatgttata actatattgt aactattttc gtaatcttag
     2401 gaaaagatta cttataaaat taaccttata caataatata tcgtataatc ttaattagca
     2461 taatagttac aatattaaaa tttaaatatg ggagtgattt tagtatgata agacaaacac
     2521 cattagagaa acgatatgac aagctaggtc ctcatattgt aacagcactc aaaaaacgtt
     2581 attttgatgc ttattactgt aaaactagaa atgaagcttt gcaacaaatt ttagatttaa
     2641 ttcctcaaaa tcatgtagta tcatggggag gatctgaaac acttaaagaa atgggcgtac
     2701 aaactgctgt tagagagaaa ggatttaaag ttattgatag agatttagca aaaactccag
     2761 aagaaagaac tgaaattatg cgtcaagcac ttctatgcga tacttttttg atgagtagca
     2821 atgcaattag tgaagatgga caactcttta atattgatgg aaatggcaat cgtgtagctg
     2881 caatgatatt tggtccaaaa aatgttatag ttgtagctgg tatgaataaa attgtaaaaa
     2941 acattgatga tgcaatacaa agaactagaa caattgcatc tccagcagtt gttcagcgtt
     3001 ttcaagatgt caatacacca tgctatatta atggaagttg tatagattgc acaagtcctg
     3061 aaagcatttg tgcatacatg gttactacaa gaatcagtcg tccagcaaaa aaaataaagg
     3121 taatattggt aggagaaaat cttggtctat aaaatataca tacatgtaaa tagctctata
     3181 aataataaaa tcatatgaaa taacttattt ctaaaagtgg tagaataaaa gcttctacaa
     3241 gactttcatt ctgccacttt tatattcttt taatttgtgt ttctatatta ttaattgctc
     3301 caattttcat atatattact aactattttt attttcataa tttttttgtt cttcatcaag
     3361 ctgtttataa taatctttat tatagtcagc tagataatct ataccacctc ctgtaatcac
     3421 atttaataat ttcattgcag attcttgatt aactttacaa acataattat caccagattt
     3481 aacaagctct aatgtaatat taaattcttt tttctttgca gaatcaatat ctttcatagt
     3541 tggatttggc atcatttctc ctagtttagg aggattcttt tttaaaatag aaaccatatc
     3601 agtattgtta atttttaaat ctacagtcac tttatcctta ttatttttta tatctgaaat
     3661 ttcccaagtc atatttttag aatacatttt aaatccttct ttatcttcgt atataagatt
     3721 acctaaccct gattttggga aatacttatc aacagtatct gcatcttgtg tttttattga
     3781 attaaacata ctatccactt cattttttat cttattatca ttagtacaac cagctaacac
     3841 cagtactgat attgcaaaca ttataataca tagaataaat ttcttcatta aattatatcc
     3901 ccctatactt ttttgcacaa atattattct cttttttatc ttttgaaaaa gttgtagtaa
     3961 ttgcattttg tggacaaact tttatacatt caccacacct aatacagtct ggactattta
     4021 catctttata tattggtata tcaagcttac attttgtttg acatgctgta caatttgtac
     4081 atttatcttt atcaatttta aatctatata ttgaaatagg attaaaaaaa ccatagattg
     4141 ctcctaaagg gcatatatac ttgcaaaatg gcctataagt aatgattgac atcaataata
     4201 tcaataacaa aatacttaac ttccagctaa ataaaaatcc tattgattct cttaaattct
     4261 catttcctaa aataagtggt attcctccca aaagtgttcc tgaagggcaa atccatttac
     4321 aaaaccaagg atttccaccc cctgctacat ttacaatagc aactggcaaa ataattacaa
     4381 atattattaa gactatatac tttagatatt ttagatattt atcaccataa acttttttta
     4441 tctttactgg aaagggtact ttatgtagta aatcttgtac aagtccaaag ggacaaagcc
     4501 aaccacaaac aaatctgcca aaaaaagcac caaatgccat taaaaaacca acaacataaa
     4561 atgagaattt atactctctg cttgataaaa ctgcttgtaa tgaacctatt ggacatgctc
     4621 caagtgcacc tggacatgaa taacaattca atccaggtac acataatttt ttactttctc
     4681 ctccatatat agttccttct aaaaatccat ttacatatcc atttgttaat gctgtaaatg
     4741 caacttgagt aataagtctt atattattat ttactttaga taataacttc attcctcttc
     4801 tcctaaccaa taccaataca ctcaagacaa atcataattg ctttagttaa tactgtattt
     4861 gtttctccac gatatgtacc taatgcaata aatataatac taattgcaat aatagaaatg
     4921 ccttttttat tatctttaat aaagttactc attggctttt accattttta gtctttcatc
     4981 tataattttt ttccaatctt ccttactatt tgcacctaca accttctcac ccacaaagtt
     5041 tcctttcttg tctacaaaat aagttgttgg aaactccata actcttttaa aatcagtttt
     5101 tttaagttct tcagatacag tcaattgttg gtaagttgca tctgactttt tcataatgtc
     5161 tttaactaaa tttttctctt catttgaaag accagttctc atatcagttt tatcaacttc
     5221 tacaactaat ccctttatag ctacattgga attattactc tcatattctt ttgataatgc
     5281 ttcaagctct ggcatttcac ccacacatgg tccacaccaa gtagtccaga cattaataag
     5341 agtaagttct ttatttgaaa atatctcttt tgttacctta tttccatcaa catcctccgt
     5401 atctaaatta ctaaaccatt cactattatt cttgtttttt tctactggct tagattcttt
     5461 tttgctacat ccagaaatca tacctaaaac acaaatacat cctaaaacta ctatgaaaaa
     5521 ccttttcata tctcacactc ctagaattta tatagtatat aaaatcgctg cttgaaataa
     5581 aaataactta tcttctatat taaagtaatt atatttaata aataagagct aatttaaaaa
     5641 aagatataca gttaaa
//
LOCUS       DAYAOO010000158         5630 bp    DNA     linear   BCT 12-OCT-2024
DEFINITION  TPA_asm: Clostridioides difficile isolate ST8-SSI-h139-18
            SAMN40601845-rid21577343.denovo.162, whole genome shotgun sequence.
ACCESSION   DAYAOO010000158 DAYAOO010000000
VERSION     DAYAOO010000158.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN40601845
            Sequence Read Archive: SRR28438827
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 5630)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5630)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-MAY-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-MAY-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002157583.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002157583.1
            Genome Coverage       :: 163x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/11/2024 16:19:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 4,038
            CDSs (total)                      :: 3,963
            Genes (coding)                    :: 3,930
            CDSs (with protein)               :: 3,930
            Genes (RNA)                       :: 75
            rRNAs                             :: 6, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 60
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 33
            CDSs (without protein)            :: 33
            Pseudo Genes (ambiguous residues) :: 0 of 33
            Pseudo Genes (frameshifted)       :: 7 of 33
            Pseudo Genes (incomplete)         :: 25 of 33
            Pseudo Genes (internal stop)      :: 11 of 33
            Pseudo Genes (multiple problems)  :: 8 of 33
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5630
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN40601845-rid21577343.denovo.162"
                     /isolate="ST8-SSI-h139-18"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Denmark"
                     /collection_date="2018"
                     /collected_by="Statens Serum Institute"
     gene            complement(753..2159)
                     /locus_tag="ACGI5H_003791"
     CDS             complement(753..2159)
                     /locus_tag="ACGI5H_003791"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892732.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing sensor histidine kinase"
                     /protein_id="HFG9699464.1"
                     /translation="MDSVKYILRRFIGSSILISLLFIVLNIAGFLLFSYMLFVSKYSD
                     NLDTSDSREIKSNLIMIEDNLILRDGKFILDDSSKEVLHKNKVWAMLIDNNGDRIWGF
                     DLPKEIPSHYTLTDVAKFSRFFLKDYPVYVWEHPNGILVTGYPKDKYTKFNLTYTVKE
                     IEQFPMLIIGMFLVNAIVTFLIALFIGLKMVKSIKPIITGIKLMSKGEPVLLQEKGIL
                     SDISKSINTVSKELQMKDEKLRKKEEARSNWIAGISHDIRTPLSMIIGYAGELEESSS
                     LSNREQEQVSIICNQGIKIRELVNDLNLVSKLEYNMQTLNCDKIRVSAFLRELISEFI
                     NNNLDNDFYVELDILNEDIIIDADKKLLKRAISNLIQNSITHNQQGCNIRVTSKSDLD
                     FCYIIVEDDGKGMSQERINSLLKSQNGLSEAYAKGQNHGLGILIVSGIINAHRGKLDI
                     TSIDSQGLKTILKLPLIK"
     gene            complement(2204..2911)
                     /locus_tag="ACGI5H_003792"
     CDS             complement(2204..2911)
                     /locus_tag="ACGI5H_003792"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000156 - phosphorelay response regulator
                     activity [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HFG9699465.1"
                     /translation="MESIKDKKILVVDDHKELLKMIDEILRKEGFSRVFLASSYEEAV
                     RVFRNVKPDCAILDVVLPDGDGFSIMRKIRETSKIPVIFLSARGEDEDRLIGLGLGAD
                     DYIVKPFLPKELTLRLVGILNRVYVPIEEEELPVFKLGDSVVVNLNSACVEKDGQEIS
                     LTAKEHSLLLKLYENKGRIVTNDSLCQAIWGDDMYGYENTLMVHVRRVREKIEKTPST
                     PKHLITVRGLGYKLMIN"
     gene            3073..3996
                     /locus_tag="ACGI5H_003793"
     CDS             3073..3996
                     /locus_tag="ACGI5H_003793"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418194.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HFG9699466.1"
                     /translation="MKHMEMIIRTQRLSKEYNKIFRVKDIDLRVPQGAVYGFLGPNGA
                     GKSTTLKMLLGLAKPTQGNINILGKELNEKNRISILKDIGSLIESPSYYGHLTGLENM
                     TIMQRLLDLPKKNVNEALKIVRLENQKNKKVSQYSLGMKQRLGIAMAIMKFPKLLILD
                     EPTNGLDPAGIEEIRELIKSLPEKYGMTVLISSHLLSEIDQIATSIGIINHGELVFQD
                     SIKELHNRGQSQIAIKTKNVVSAQKLLNTKGYMSLIQDGYLTIENLKDSDVAKINGML
                     VHSNIDVFRIEEHKKSLEDIFLELTGKAVTL"
     gene            3996..4757
                     /locus_tag="ACGI5H_003794"
     CDS             3996..4757
                     /locus_tag="ACGI5H_003794"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418193.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HFG9699467.1"
                     /translation="MKYLGLEFYKLKRKKIILMTFLFAAVEIMWCIVNSNRAITRNPD
                     MLGGFEYSYMLMSFASLNGLFFPILISIITSRISDIEHKGDTWKLLKSSVTSLNSIYL
                     SKFLCSAILVSIPVLMQVLSIVLFGHFRGVIESISVSLLLKYTLGTILVSIAIIALHL
                     WIATVIPNQMIAITFGMIGSFIGLTSGLFYQGIRRLFIWSYYLELSPLSYAYDNVLGS
                     SVYRIDMNFSITILVFLIGMLIYYIGRNHLLKKEV"
     gene            4769..5506
                     /locus_tag="ACGI5H_003795"
     CDS             4769..5506
                     /locus_tag="ACGI5H_003795"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HFG9699468.1"
                     /translation="MLRKSVLGEILKLKNSFIWYVLLALPLISVLIGSGNFYLNQGIL
                     KKEWYSLWTQVSLFYGEFFFPILIAIFCAYICRLEHMNHNWNNVMTLPVNLKNIFLSK
                     LTVVSILTAITQVFFVIFYIVAGNMFGFSGSVPKELTGWIAKGWIISISIASIQLYMS
                     IKIRSFATPIGISLCLSLFGMGLIVAKPAVGIFFPYSMLGSAMGVIKQSALNVNDTIV
                     TICVAFITTIVFSEIANRNFRKNDVIS"
BASE COUNT         1948 a          860 c          708 g         2114 t
ORIGIN      
        1 actaaacttc ctactttcta aatttcttgc ttcttaagaa taatgttaat tttaatttta
       61 agattatagt ttttaccttg tttaattgaa acattctata taattatatc cttctatttt
      121 agagtttttt tatttatata ttacaaagtt taaatttttt cattaattat attataaatt
      181 ttccatatat ttcaacataa atacatatat atatatgtta tttctaaaaa tactacacaa
      241 aaactctact ttagtagaac tcaatggcgc aaaatacttc aatttaaaac atttatcgta
      301 ctttaaataa ataactataa taaaatatac ttacaatagt tacatagaag ctattataac
      361 tacacagaac agcttataat taaaactttt ttaggatgtc attatatttt ttcttaaaat
      421 taaaaaacac tataccataa ttctatttta gtagaatttt tttgtcaata ataaaattaa
      481 atattaacta aaaaataaaa aaaatggaat tatctaaaga atttaataac cttacaataa
      541 ttccaaaata ttatttctat gaaaattttg ataccatgag taactcagcc ataagcgcat
      601 aaagcacaag ttactcttta ctttaataaa acttgacaag aaaagaattt atccttattc
      661 tactctaata gagttaattt gtcaataaag aataaaatta ttttcaaaat attttcattc
      721 ttcattctta tctgttatta ttttataaaa tatcacttaa ttagaggtaa ttttagtatt
      781 gtttttagtc cctgactatc aatgctcgta atatctaatt tacctctatg tgcattaata
      841 atgccagata ctatcaaaat acctagacca tgattttgac ctttggcata tgcctcactt
      901 agtccatttt ggctctttaa taaactatta attctttctt gactcatacc ttttccatca
      961 tcttcaacaa ttatatagca aaaatctaaa tcagacttag aggtaaccct tatattacat
     1021 ccttgttggt tatgagttat actattttgt attaaattac taatagccct ttttaataat
     1081 tttttatctg catctataat aatatcttca tttagtatat caagttcaac gtaaaagtca
     1141 ttatccaaat tattatttat aaactcagaa ataagctctc tcaaaaacgc agaaactcta
     1201 atcttatcac aattcaatgt ttgcatatta tattcaagtt tagacactaa atttaggtca
     1261 tttactaatt ctctgatttt aatcccttga ttgcatataa tagacacttg ctcttgttct
     1321 ctatttgaaa ggctactgct ttcttcaagt tctccagcat atccaattat cattgaaagt
     1381 ggagttctta tatcatgaga tattcctgca atccagttag acctagcttc ctctttcttc
     1441 ctaagttttt catctttcat ttgcaactct ttagatacag tattaataga ttttgaaata
     1501 tcacttagta ttcctttttc ttgtaaaagt actggttctc cttttgacat aagctttatg
     1561 ccagtaataa ttggttttat agatttcacc atttttaaac ctatgaatag agctattaaa
     1621 aaagtaacta ttgcattaac cagaaacata cctattatta acataggaaa ttgttctatt
     1681 tccttaaccg tataagtaag gttaaactta gtatacttgt cttttggata acctgttact
     1741 aatattccat ttggatgttc ccatacatac acaggatagt cctttaaaaa gaaccttgaa
     1801 aactttgcta catctgtcaa agtataatga cttggaattt cttttggtaa atcaaatccc
     1861 catattctat ctccattgtt atcaattaac attgcccaaa ctttattttt atgtagtact
     1921 tccttactag aatcatctaa aataaacttt ccatctctta aaatcaaatt atcttcaatc
     1981 ataatcaagt ttgattttat ttctctacta tcacttgtat ctaaattatc agagtattta
     2041 gatacaaata acatatatga aaacagaaga aaacctgcta tatttaatac aataaaaagt
     2101 aatgaaatca agatacttga acctataaat cgcctcaata tgtactttac actatccaaa
     2161 attaaatcac tcctcttgat ttcttttatt ctaatatcta aaattaatta atcatcaact
     2221 tatatccaag acctcttact gtaataagat gtttaggtgt agatggagtt ttttctatct
     2281 tctctctaac ccttctaaca tgaaccataa gggtattttc atatccatac atatcatctc
     2341 cccaaatggc ttgacatagt gaatcattag taacaattct ccctttattt tcatacaact
     2401 ttaaaagcaa cgaatgctct ttagctgtta aagaaatctc ttgcccatct ttctcaacac
     2461 atgcactatt taaattcaca acaacagaat ctcccagttt aaatactggc aactcctctt
     2521 cttctatagg cacatataca cgatttaata tacccacaag ccttaaagta agttcctttg
     2581 gtaaaaatgg ctttactata taatcgtcag cccctaagcc caaaccaatc aatctatctt
     2641 catcttcacc tcttgcagag agaaaaatca ctggtatttt agatgtctct ctaatttttc
     2701 tcataataga aaaaccatct ccatctggca atacaacatc taaaattgca caatctggct
     2761 ttacatttct aaatacccta acagcttcct cataacttga tgctaaaaat actctactaa
     2821 atccctcttt tctcaggatt tcatctatca tttttaataa ttccttgtgg tcatcaacca
     2881 caagtatttt tttatctttt attgactcca taatcatcac cctcctttag tataccatat
     2941 acccattttc acaactttgc ctaaatagac ttttaaggtt attgtaaggt aaatttcagc
     3001 taattgaaat gtaaccaagt tattatactg atataagtta aaagaatcaa taagcacaga
     3061 ttaaaaaagg ggatgaaaca tatggaaatg ataattagaa cacaaagact ttcaaaggaa
     3121 tacaataaaa tatttagagt aaaggatata gacctaagag ttccacaagg agctgtatat
     3181 ggttttttgg gtcctaatgg agctggaaaa tctaccactc ttaaaatgct tcttggactt
     3241 gctaaaccca cacaaggaaa tattaatatt ttaggtaaag agttaaatga aaaaaataga
     3301 atatcaattt taaaagatat aggttctttg atagaatctc catcatacta tggtcatctt
     3361 acagggcttg aaaacatgac cataatgcaa agactcttag atttacctaa aaaaaatgta
     3421 aatgaagcat taaaaattgt aaggttagaa aatcaaaaaa ataaaaaagt tagtcaatat
     3481 tctttaggta tgaagcaacg tcttggcatt gctatggcaa taatgaagtt tcccaaatta
     3541 ttaatacttg atgaacctac aaatggactc gacccagcag ggattgagga aattagagaa
     3601 ttaataaaat ctctaccaga aaaatacggg atgactgttc taatctctag ccatctttta
     3661 agtgaaattg accaaattgc cacatcaata ggaataataa atcatggcga actggttttt
     3721 caagatagca taaaagaact tcataataga ggtcaaagtc agattgctat caaaactaag
     3781 aatgttgtat ctgcacaaaa actattaaat actaaaggat atatgtcact tatacaagat
     3841 gggtacttga ctattgaaaa tttaaaagac tcagatgtcg ctaaaataaa tggtatgctt
     3901 gtccattcaa atatagatgt atttagaata gaagaacata aaaaaagctt ggaagatata
     3961 ttcttagaac ttactggtaa ggcggtgact ttataatgaa ataccttggt ctagaatttt
     4021 ataaacttaa aagaaagaag attattctga tgaccttttt atttgcagct gttgaaataa
     4081 tgtggtgtat cgtaaattca aatagagcta ttacacgtaa tccagatatg ttaggtggat
     4141 ttgaatattc ctatatgctt atgagttttg caagtttaaa tggtctattc tttcctatct
     4201 taatatcaat aattacatca cgtataagcg atatagaaca taaaggagat acatggaagc
     4261 ttttaaaatc ttctgtgaca tctttaaata gtatttattt atctaaattt ttatgttctg
     4321 ctattttggt atctatacct gtattgatgc aagtgttatc tattgtgttg tttggacatt
     4381 ttagaggggt tattgagtca atttctgtat ctttactttt aaaatacaca ttaggaacaa
     4441 ttcttgtaag tattgctatc attgcactac acctatggat tgcaactgta attccaaatc
     4501 aaatgattgc aattacattt ggcatgattg gtagttttat aggtttgaca tcaggtttgt
     4561 tttatcaagg tattcgtaga ttgtttatat ggtcttatta cctagagtta tcacctttaa
     4621 gttatgctta tgataatgtt ttaggttcat ctgtctatag aattgatatg aatttttcta
     4681 ttacgatttt agttttctta attggaatgc taatttatta tattggaaga aatcatttat
     4741 taaaaaaaga agtataggag ggatttaaat gttaaggaag tcagttttgg gagaaattct
     4801 aaagttaaaa aattctttta tatggtatgt attattagct ttgccactta taagtgtgtt
     4861 gattggttct ggtaattttt atctaaatca aggcatactc aaaaaagaat ggtacagctt
     4921 atggactcaa gttagtcttt tttatgggga atttttcttt cctatcttaa tcgcaatctt
     4981 ttgtgcatat atttgtaggc ttgaacatat gaatcataat tggaataatg taatgacact
     5041 gccagttaat ttaaaaaata tctttttatc taaacttaca gtagtttcaa tacttacagc
     5101 tattacacaa gttttctttg ttatctttta tatagttgca ggaaatatgt ttggtttttc
     5161 tggtagtgta cctaaagaat tgactggttg gattgctaaa ggttggatta tttctatttc
     5221 aatagcttct atacaattat acatgtctat aaagattaga agttttgcaa ctcctattgg
     5281 tattagtctt tgcctttctc tatttggtat gggattaata gtagcaaaac ctgctgttgg
     5341 tatatttttc ccttattcta tgttaggtag tgctatgggg gttataaagc aatctgcttt
     5401 aaatgttaat gacactatag ttacaatatg tgttgcattt attactacta tagtattttc
     5461 tgaaattgcc aatagaaatt ttagaaagaa tgatgttatt tcttaatggt aaatgctaga
     5521 tatttttggg tttgaaattt atattctttt tagttgaaat ctatatccat tttatttaaa
     5581 aatatatatc ttttatttga attttatatg ttttatctac tcgctatata
//
LOCUS       DAYAOO010000159         5427 bp    DNA     linear   BCT 12-OCT-2024
DEFINITION  TPA_asm: Clostridioides difficile isolate ST8-SSI-h139-18
            SAMN40601845-rid21577343.denovo.163, whole genome shotgun sequence.
ACCESSION   DAYAOO010000159 DAYAOO010000000
VERSION     DAYAOO010000159.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN40601845
            Sequence Read Archive: SRR28438827
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 5427)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5427)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-MAY-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-MAY-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002157583.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002157583.1
            Genome Coverage       :: 163x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/11/2024 16:19:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 4,038
            CDSs (total)                      :: 3,963
            Genes (coding)                    :: 3,930
            CDSs (with protein)               :: 3,930
            Genes (RNA)                       :: 75
            rRNAs                             :: 6, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 60
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 33
            CDSs (without protein)            :: 33
            Pseudo Genes (ambiguous residues) :: 0 of 33
            Pseudo Genes (frameshifted)       :: 7 of 33
            Pseudo Genes (incomplete)         :: 25 of 33
            Pseudo Genes (internal stop)      :: 11 of 33
            Pseudo Genes (multiple problems)  :: 8 of 33
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5427
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN40601845-rid21577343.denovo.163"
                     /isolate="ST8-SSI-h139-18"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Denmark"
                     /collection_date="2018"
                     /collected_by="Statens Serum Institute"
     gene            <1..222
                     /locus_tag="ACGI5H_003796"
     CDS             <1..222
                     /locus_tag="ACGI5H_003796"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419656.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2634 domain-containing protein"
                     /protein_id="HFG9699469.1"
                     /translation="IYSWGYGTELAELIGQKYSKGLTESEASRYIKEALLVNPYILDV
                     NVKNTKFTDDLLSVDIIINTIYGEVEVNV"
     gene            215..1261
                     /locus_tag="ACGI5H_003797"
     CDS             215..1261
                     /locus_tag="ACGI5H_003797"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429314.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="baseplate J/gp47 family protein"
                     /protein_id="HFG9699470.1"
                     /translation="MYSSQTYDVVKNRTLSNINLDIYKGEGSFLSDMVSPVNSELAKF
                     YIELSYLHKKAFIEDNFDDFLDKRVNEFGVYRKLGTEATGEVTFEGKVGTVIPNGTII
                     SYNELLFVVIKDIVISSEIEQNISPVQALEIGIRYNIPANTEFKLDEINGITRIYNNL
                     DFKGGTEIETDEELKERFYKIQKNQATSGNKAHYEAWALEVEGVYNAKIYPRWDGPGT
                     IKVLIFGENNQAVDTEVIERCKEHIEEEMPIGPALTVLTPSVLDISISASIKLEAGYT
                     LDFVKESFLESINSYLINVNKEIIYTKVSAILAGTEGLHDFSNLLLNNKTENIVFEED
                     KVPSVTTLEFSEVV"
     gene            1262..1879
                     /locus_tag="ACGI5H_003798"
     CDS             1262..1879
                     /locus_tag="ACGI5H_003798"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894591.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative phage tail protein"
                     /protein_id="HFG9699471.1"
                     /translation="MKLIDKLPSFYNNDITSKIQEAYDIELSTLRETYDDTFDQFFVD
                     TATWGLDYWENILSIKNRFDLNIEDRRSNIKAKMRGKGTTTAEVVKAISEAYTKTDVD
                     VKVFSNLFSFTLSFITNDCSYNTILELDKKIEEIKPAHLEHKFEMILFNQNDMFAGST
                     MNTGETVTIYPYSPTDITSFGELTITTGNDRSMEKVTLYPRQEVV"
     gene            1881..2882
                     /locus_tag="ACGI5H_003799"
     CDS             1881..2882
                     /locus_tag="ACGI5H_003799"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015984856.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HFG9699472.1"
                     /translation="MAEQKYYTLLTTIGKASIANATALGNKVDLVKLQLGDGAGTEYN
                     PTEEQTSLKNVVWEGSVNNVKIDEENPNWIVIETVIPGSVGGFMIREVGIFDSKEQLI
                     AVSKYPETYKPTADSGSVKDLVIKIILVVSNTSSVNLKVDPTVILATLKDIQDLDSKI
                     DTTKTELTSNIETTKTELNTRIDTENEKQNIKIDQLIAGGSNVASTQTITIDDWVEDA
                     ENGFKATVTHSLLTHRIVVNIIDATTKENIVPNFKIVDDNSIEIRSEVKVELNVYVIN
                     GNAETHFINATVDDNRVSEMTTYSSKKIEDRLVNIEEKVNGGLSNIATSVNELITYC"
     gene            2899..4611
                     /locus_tag="ACGI5H_003800"
     CDS             2899..4611
                     /locus_tag="ACGI5H_003800"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009901445.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine-rich protein"
                     /protein_id="HFG9699473.1"
                     /translation="MQTEWNFNYANYVQNVSLPPGRYKLECWGACGGAVDTSDWTDCA
                     KGGYSKGEIVFKKRTNLQICVGQSGYEKVSEGSSLTRSGFNGAGAAGKVTTGSFAYSK
                     YGGGATDIRLYHPSATWGNTESLLSRILVAGGGGGMKNNFASARSIGHGGGYVGVNGV
                     GRDRDFCGGGSQYQGGTSYDTEEYHGSLGKGGYGNIGIGGGGGWYGGAGSYSNECGGG
                     GSGYALNKDSYKAPGYIPTPEYYLENIVMTTGGNTTKADGYAKITLLQALPFLTVSSY
                     NSTQATFKADHTDPALLTKIEWFIDDVLKETITTNLTEEKTINYTLEDNALHTLKIVV
                     TDSNNATAEKVLSISKNIMPLPENVNLNDISTKLVEVNAGFKVGKTSIINTLALKNIE
                     ASLNNTLVELSEKIKTSFDSSDTSVQDLQNQVTQKNNTITQLETELSKRKRFITGTYT
                     FTKTDAENFNLSIYDKEGTSKTLTIPVNMGFSPSLIVLSGVTFSTTSKSYVYFDNVCN
                     SNFYNFGYNSDSTHSNPKAVGILNVSNVGYSSLVLTLYKLSMSEAVGIWAKEGATLTY
                     KIYI"
     gene            4632..4979
                     /locus_tag="ACGI5H_003801"
     CDS             4632..4979
                     /locus_tag="ACGI5H_003801"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429875.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9699474.1"
                     /translation="MNRNNRIIYDQTGNIWLQTGEATGDIQEWSKITELNFLDVEFGS
                     IDYSKQYIESINPVTKEPIIKDIEVILTDEQKRLQALEKELSMLKEENKNRDSEIVNT
                     AFEVENIKLNNNL"
     gene            4991..5161
                     /locus_tag="ACGI5H_003802"
     CDS             4991..5161
                     /locus_tag="ACGI5H_003802"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429877.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9699475.1"
                     /translation="MYNLLKLMIEQKNYSTKEDLQHKIDVFYAVNRITEEQYLELTSL
                     LNKEETPAEPIK"
     gene            5192..>5427
                     /locus_tag="ACGI5H_003803"
     CDS             5192..>5427
                     /locus_tag="ACGI5H_003803"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728849.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9699476.1"
                     /translation="MTFKELVNKVRNLVLEAKNVTIEDTENNFTSDNVEGALKEVFQN
                     GVNAKNNVVTALNSKGAEITTNNTWEEIKNKVNN"
BASE COUNT         2183 a          639 c         1033 g         1572 t
ORIGIN      
        1 atttatagct ggggttatgg gacagaatta gctgaactaa tagggcagaa atatagtaaa
       61 ggacttacag aaagtgaagc tagtagatat ataaaagagg ctttattagt taatccatat
      121 atattagatg tcaatgtcaa gaatacaaaa tttacagatg atttactaag tgtagatata
      181 atcataaaca cgatttatgg ggaggtggaa gttaatgtat agtagtcaaa catatgatgt
      241 tgtgaaaaat aggaccttgt caaatataaa tttagatatc tataagggtg agggttcttt
      301 tttaagtgat atggtatctc ctgttaatag tgagttagca aaattctata tagaactttc
      361 atatcttcat aaaaaagcat ttattgagga taatttcgac gattttcttg ataaacgggt
      421 aaatgagttt ggagtatata gaaagttagg aacagaagca actggagagg tgacattcga
      481 ggggaaggtc ggaacagtca taccaaacgg aactattata tcttacaatg agctattatt
      541 cgtagtaatt aaagatatag taattagttc agaaattgaa caaaatataa gccccgtaca
      601 ggctttagaa attggaatta gatataatat acctgcaaac acagaattta agctagacga
      661 aataaacggt ataacaagaa tttataataa tttagacttt aaaggtggta cagaaatcga
      721 aacagacgaa gaattaaaag aaagattcta taaaatacaa aaaaatcaag caacaagtgg
      781 aaataaggca cactatgaag catgggcttt agaagttgaa ggagtatata acgctaaaat
      841 ttatccaaga tgggatggtc caggaacaat taaagtttta atctttggag aaaataatca
      901 agctgttgac acagaagtaa ttgaaagatg caaagaacat attgaggaag aaatgccaat
      961 aggtcctgcg ttaaccgttt taactccaag cgttttagat ataagtataa gtgcatctat
     1021 aaaattagaa gcgggatata cattagattt tgtaaaagaa agcttcttag agagtattaa
     1081 tagctattta ataaatgtta ataaagaaat aatttacact aaagtaagtg caatacttgc
     1141 aggtacagaa ggcttacatg actttagtaa tttattatta aataataaaa ctgaaaatat
     1201 agtatttgaa gaggataaag tcccaagtgt tacgacttta gagtttagtg aggtggttta
     1261 attgaaatta attgataagc taccttcttt ttataacaat gatattacta gtaaaataca
     1321 agaagcttat gacatagaac tgagcacact tagagaaaca tatgatgata cattcgacca
     1381 gttttttgta gatacagcca cttggggatt ggattattgg gaaaatattt tatctattaa
     1441 aaatagattt gatttaaata tagaagatag aagaagcaat ataaaagcaa agatgcgtgg
     1501 taaaggtaca actacagcag aggttgtaaa agctatatca gaagcttata caaaaacaga
     1561 cgtagatgta aaagtattta gtaatctatt tagttttaca cttagtttta taacaaatga
     1621 ctgtagttat aacactattt tagaattaga taagaaaata gaagaaataa aacctgcaca
     1681 tcttgaacat aaatttgaaa tgattttatt taatcaaaat gatatgtttg caggttctac
     1741 aatgaataca ggtgaaacag ttactatata tccttacagt ccaactgata taacttcttt
     1801 tggagaattg actataacta caggcaatga tagaagtatg gaaaaagtaa cattatatcc
     1861 tagacaggag gtggtatagg ttggcagaac aaaaatatta tacacttttg acaacgatag
     1921 gaaaagcatc tattgcaaat gcaacagctt taggcaataa agtagattta gttaaattgc
     1981 agcttggtga tggagcaggg acagaatata atccaacaga agaacaaacg tctctgaaaa
     2041 atgtagtttg ggaaggttct gtaaataatg taaagataga cgaagaaaat ccaaactgga
     2101 tagtaataga aactgtaatc ccaggtagtg tgggtggttt tatgataaga gaagtaggga
     2161 tatttgattc aaaagaacaa ctaattgcag tgtctaaata tccagaaaca tacaaaccaa
     2221 ctgctgactc agggagtgta aaagacttag ttataaaaat tattttagta gtctctaata
     2281 cttcaagtgt aaatttgaaa gtagacccaa ctgttatttt agcaacactt aaagatatac
     2341 aagatttaga ctctaaaatt gatacaacta aaacagaatt aacaagcaac atagaaacta
     2401 ctaaaacaga gttaaacact agaattgaca cagaaaatga aaaacaaaat attaaaattg
     2461 accaattaat cgcaggtggt tcaaatgtgg catctactca aacaataaca attgacgatt
     2521 gggttgagga tgcagaaaat ggattcaaag caactgtaac acatagttta ttaacacata
     2581 gaatagttgt aaatattata gatgctacta caaaagaaaa tatagttcca aattttaaaa
     2641 tagttgatga taattcaatt gagattagaa gtgaagtaaa agttgagtta aatgtctatg
     2701 tgataaatgg aaatgcagaa actcatttta taaatgcaac tgtagatgat aacagagtat
     2761 ctgaaatgac tacttattca tctaagaaaa tagaggacag attggttaat atagaagaaa
     2821 aggtaaatgg tggtttatct aatattgcaa caagtgtaaa tgagttgata acttattgtt
     2881 agagaggaga gtgagaaaat gcagactgaa tggaatttta attatgctaa ttatgtacaa
     2941 aatgtttcat tgccacctgg gcgatataaa ttagaatgtt ggggtgcttg tggtggtgct
     3001 gtcgatacaa gcgattggac tgattgtgca aaaggtggtt attcaaaagg tgagattgta
     3061 tttaaaaaaa gaactaatct acaaatttgt gtcggtcaat ccggttatga gaaagtttct
     3121 gaaggttcaa gccttactag aagtggtttt aacggtgcag gcgctgctgg caaagttact
     3181 actggtagct ttgcttattc taaatacggt ggtggagcaa ctgatataag actttatcat
     3241 cctagtgcaa cttggggtaa cactgaaagt ttgctttcac gcatacttgt tgcaggcggt
     3301 ggaggaggta tgaaaaataa ttttgcttct gctcgttcta ttggtcatgg tggtggttat
     3361 gtaggtgtta atggagttgg tcgtgacaga gatttttgtg gcggtggttc tcaataccaa
     3421 ggtggaacaa gttacgacac agaagaatac catggttcat taggaaaagg aggttatggt
     3481 aacataggaa taggtggtgg agggggttgg tacggtggtg ctggttctta ttctaatgaa
     3541 tgtggaggtg gtggaagtgg ttacgcacta aataaagata gttataaggc acccggatat
     3601 ataccaacac ctgaatatta tcttgaaaat atagtcatga ctactggagg taatactact
     3661 aaagcagatg gttatgctaa aataacatta ctacaagcat tgccattttt aacagtatct
     3721 tcttataatt ctacacaggc aacatttaaa gccgaccaca cagaccctgc attacttaca
     3781 aagatagaat ggtttataga tgatgtacta aaagaaacta taacaacaaa tttaacagaa
     3841 gagaaaacaa ttaattatac attagaagat aatgcattac acacacttaa aatagttgtt
     3901 acagacagta ataatgctac agcagaaaaa gtgttaagta taagtaagaa tataatgcca
     3961 ctgcccgaaa atgtaaattt aaatgatata tcaacaaaat tagttgaggt taatgcagga
     4021 tttaaagttg ggaaaacaag tattataaac actttagcac ttaaaaatat agaagcaagt
     4081 ttaaataata cacttgtgga gttatcagag aaaataaaaa caagttttga tagttcagac
     4141 actagtgtgc aagatttaca aaatcaagta acacaaaaaa acaatactat aactcaatta
     4201 gaaacagagt taagtaaaag aaaaagattt ataacaggaa cttatacatt cacaaaaacg
     4261 gatgcagaga attttaactt aagtatatat gacaaagaag gaacttcaaa aactcttact
     4321 ataccagtta acatgggctt ctctcctagt ttaattgtac ttagtggagt aacttttagt
     4381 acaacaagta aatcttatgt ttattttgat aatgtttgta attcaaattt ttataatttt
     4441 ggctataatt ctgattctac tcatagtaac ccgaaagctg ttggtattct taatgtatct
     4501 aatgttgggt attcttcatt agtgcttaca ttatataaat tatcaatgtc agaagcagtt
     4561 ggaatatggg caaaagaggg agctacatta acttacaaaa tatatattta ataaaaaaat
     4621 gaggtgataa tatgaacaga aataatagaa taatttacga ccaaacaggc aatatatggc
     4681 ttcaaactgg tgaagcaaca ggagatatac aagagtggtc aaaaataact gaattaaatt
     4741 ttttggatgt tgaatttggt agtatagact atagtaaaca atatatagag tctataaatc
     4801 cagttacaaa agaaccaatc atcaaagaca tagaagtcat tttaacagat gaacaaaaga
     4861 gattacaagc attagaaaaa gaattaagca tgttaaaaga agaaaataaa aatagagata
     4921 gtgagatagt aaacacagcc tttgaggtag aaaatataaa attaaataac aatttatagg
     4981 aggaattaac atgtataact tattaaaact tatgatagaa caaaagaact atagcactaa
     5041 agaggatttg caacacaaaa ttgatgtatt ctatgcagta aatagaatta cagaagaaca
     5101 atatttagaa cttacaagtt tattaaataa agaagaaaca ccagcagaac caataaaata
     5161 ggttcttttt ttattgaaag aaggtgacta aatgactttt aaagagttag ttaataaagt
     5221 tagaaatctt gtattagaag caaagaatgt aactatagaa gatacagaaa ataactttac
     5281 aagtgataat gtagaaggag cattaaaaga ggtttttcaa aatggagtta atgctaaaaa
     5341 taatgtagta acagcattga actccaaggg tgcagagatt actacaaata acacttggga
     5401 ggaaataaag aataaagtaa acaacaa
//
LOCUS       DAYAOO010000160         5352 bp    DNA     linear   BCT 12-OCT-2024
DEFINITION  TPA_asm: Clostridioides difficile isolate ST8-SSI-h139-18
            SAMN40601845-rid21577343.denovo.164, whole genome shotgun sequence.
ACCESSION   DAYAOO010000160 DAYAOO010000000
VERSION     DAYAOO010000160.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN40601845
            Sequence Read Archive: SRR28438827
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 5352)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5352)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-MAY-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-MAY-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002157583.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002157583.1
            Genome Coverage       :: 163x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/11/2024 16:19:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 4,038
            CDSs (total)                      :: 3,963
            Genes (coding)                    :: 3,930
            CDSs (with protein)               :: 3,930
            Genes (RNA)                       :: 75
            rRNAs                             :: 6, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 60
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 33
            CDSs (without protein)            :: 33
            Pseudo Genes (ambiguous residues) :: 0 of 33
            Pseudo Genes (frameshifted)       :: 7 of 33
            Pseudo Genes (incomplete)         :: 25 of 33
            Pseudo Genes (internal stop)      :: 11 of 33
            Pseudo Genes (multiple problems)  :: 8 of 33
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5352
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN40601845-rid21577343.denovo.164"
                     /isolate="ST8-SSI-h139-18"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Denmark"
                     /collection_date="2018"
                     /collected_by="Statens Serum Institute"
     gene            complement(204..1388)
                     /locus_tag="ACGI5H_003804"
     CDS             complement(204..1388)
                     /locus_tag="ACGI5H_003804"
                     /EC_number="2.6.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436323.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008483 - transaminase activity [Evidence
                     IEA];
                     GO_function: GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA];
                     GO_process: GO:0009058 - biosynthetic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal phosphate-dependent aminotransferase"
                     /protein_id="HFG9699477.1"
                     /translation="MLSKRLNFITPSYTIGISSKVKEMESNGVKVINLSIGEPDFNVP
                     NNAKSYGIDSLNKDYTKYDLVPGLKILREEICKKLIEENNCNYSIDEIVVSSGAKNSI
                     TNTLLALTDEGDEVLLPKPYWVSYPEMVKLVNAVPVFIDTKKENGFKLTKDELEKSIT
                     DKTKILVINNPSNPTGSVYTKDELIEIVDVCIQNKIYILADEIYEKICYTGEFTSIAS
                     LSEEAKDITITINGFSKSAAMTGLRLGYTASNKTIAKAMSSIQGHLISHPSLTAQYIA
                     YGALKDCSIDIDNMVKTYKSRRDLIKSKLDSIDNVGYVNPNGAFYIFIDLSKVSEKFE
                     YKDSFSIEFCNQFLEEYNVAVVPGIAFGMDKYIRISYACSENTFLSGLDKLKEFVYKI
                     MA"
     gene            1761..4112
                     /locus_tag="ACGI5H_003805"
     CDS             1761..4112
                     /locus_tag="ACGI5H_003805"
                     /EC_number="1.17.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728903.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008998 - ribonucleoside-triphosphate
                     reductase (thioredoxin) activity [Evidence IEA];
                     GO_process: GO:0006260 - DNA replication [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="anaerobic ribonucleoside triphosphate reductase"
                     /protein_id="HFG9699478.1"
                     /translation="MVEFVKKRDGRVIPFNEDRITRAIFLAATNVAEREGIVPDYKLS
                     EQLTQEVIKFLNHKYSESVPSVEDIQDSVVKVLIETGHAKTSEEYIIYRTERSRIRNS
                     KTRLMKAIEEITFEDAEDADIKRENANINGNTAMGTMLQYGSTVSKEFCKTHILKPEH
                     SFAHDNGDIHIHDMDFLNMGTLTCCQIDVKKLFNGGFSTGHGFLREPQDIISYGALAA
                     IAIQSNQNDQHGGQSIPFFDYGLAEGVYKTFKKFYIGNLAKALKLFKGIENNDVIKNI
                     VYNTEKETNQKVGLKRDELYLNLEKEKLIQTFDIDDELVNKMQNFAFEESYRETDKKT
                     YQSMEAFIHNLNTMHSRAGAQVPFSSVNFGTDTSEEGRMVTKNLLLSQERGLGNGETP
                     IFPILIFKVKEGINLNPEDPNYDLFKLSCRVSAKRLFPNFSFLDAPFNAKYYKKGEPD
                     TEATYMGCRTRVLSNVCGSETVSGRGNISFTTVNLPRLGIKHGIINNEKANLDGFFEE
                     LDEKINLIIEQLLERLEVQGNKKMKNFPFLMGQGVWKGSDDLGPEDTLKEVIKQGTLT
                     IGFIGLAECLIALIGKHHGESKEAQELGLKIVSHMRHKMDEATDKYKLNFSLMGTPAE
                     GLSGRFTKIDKKVYGEIKGITDKEYYTNSFHVPVYYNISAYDKIEIEAPYHELTNAGH
                     ITYVELDGDPSDNLEAFETVIKAMKDLGIGYGSINHPVDRDPICGFSGVITSNICPVC
                     GRNEDESDIKFERIRRITGYLVGTVDRFNNAKKAEVRDRVKHR"
     gene            4134..4673
                     /gene="nrdG"
                     /locus_tag="ACGI5H_003806"
     CDS             4134..4673
                     /gene="nrdG"
                     /locus_tag="ACGI5H_003806"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003432598.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0043365 -
                     [formate-C-acetyltransferase]-activating enzyme activity
                     [Evidence IEA];
                     GO_function: GO:0051539 - 4 iron, 4 sulfur cluster binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="anaerobic ribonucleoside-triphosphate reductase
                     activating protein"
                     /protein_id="HFG9699479.1"
                     /translation="MKIRMSSTISYDSIVDGPGLRMVIWTQGCIHNCKECHNPQTHDL
                     CGGFYMDTEEIINKVKSLKLQKGITLSGGEPFLQPEPLEEIAREAKINGLDVWSYTGF
                     TFEQLLDKKNRAYFKNLNLLKQIDILVDGKFIAEKKDISLKFRGSSNQRIIDVQKSLK
                     YKKVFLVEQYMKDDLSIAE"
BASE COUNT         2097 a          598 c          851 g         1806 t
ORIGIN      
        1 ttataataaa tttagaattt aacttatata gtttaatttg ataatttgat gaaaaaaata
       61 aaagacttac tgatttttaa atctataggt cttttatttt ttatctaaca tttaaattaa
      121 gttgttgaat atatcttata ttacttacct tatatattaa ttaccattaa tacattatat
      181 ctaattacta ttcatctaaa ttattatgcc attattttat atacaaattc ttttaattta
      241 tctaatccag ataagaaagt attttcactg caagcatagg atatacgaat atatttatcc
      301 ataccaaatg ctatgccagg aacaactgca acattatatt cttctaaaaa ttgattacaa
      361 aattctatag aaaaactatc tttatattca aatttctcag atactttaga aagatctata
      421 aatatataga atgcgccatt tggattcaca tatcctacat tatcaataga gtctagtttt
      481 gatttaatta aatctcttct tgatttatat gttttaacca tattgtctat gtcaattgag
      541 caatctttca aggctccata ggctatgtat tgtgctgtta gacttgggtg agatataaga
      601 tgtccttgta tagaactcat tgctttagca atcgttttat tagatgcagt atatcctaat
      661 cttaatccag tcattgcagc tgacttagaa aaaccattta tagttattgt tatatcttta
      721 gcttcttcgc ttaatgatgc aattgatgta aattcaccag tgtagcatat tttttcatat
      781 atttcatctg ctaaaatata tattttattt tgtatgcata catctactat ttctattaat
      841 tcatcttttg tataaacact accagtagga tttgaaggat tgtttattac aagaattttt
      901 gttttatctg ttatagattt ttcaagttca tcttttgtta acttaaatcc attttctttt
      961 ttagtatcaa taaaaactgg aacagcatta actaacttaa ccatttcagg ataactaacc
     1021 caataaggct ttggtaataa gacttcatct ccttcgtctg ttaaagctag taaagtattt
     1081 gttattgagt tttttgctcc acttgataca actatttcat ctattgaata gttacagtta
     1141 ttttcttcaa taagtttttt acagatttcc tctctaagta tttttaatcc tggaactaaa
     1201 tcatatttag tgtaatcttt atttaaagaa tcaataccat aagattttgc gttattaggt
     1261 acattaaaat cgggttctcc tatactaaga tttattactt taactccatt actttccatt
     1321 tctttaactt tagaactaat acctattgtg taggatggtg ttataaagtt tagtcttttt
     1381 gataacataa aatgcctcct tttaaattat tatttatatt atacgacaaa tttaaagaat
     1441 ttacataagg aaatttgtag atatatacat taatatatat aatagcctac actttttgcc
     1501 taaaattagt gtaaaaaaaa gagaaaaaaa ttttaacttt caaagttgtt agaaacgcta
     1561 ctgttcaaaa tatccacata gtatttgcaa tgatttgcgc aagtttgact attatgtaca
     1621 aatttggtaa tcttaatata gcaattatta agataatccc tttaacttag ttgaagggga
     1681 tttttttaga cttaacatac tacatatagt ggtatgggga ttaataaaat acaatatata
     1741 gtaacaggag gtttttttaa ttggttgaat tcgtaaaaaa aagagatgga agagtaattc
     1801 catttaatga agatagaata acaagagcta tatttttagc agcaacgaat gttgcagaaa
     1861 gagaaggaat agtacctgat tataaattat ctgagcaatt aactcaagaa gtaataaagt
     1921 ttttaaatca taaatactca gaatcagttc caagtgttga agatatacaa gattctgtag
     1981 ttaaggttct tatagaaact ggccatgcaa aaactagtga agaatatata atatacagaa
     2041 ctgaaagaag tagaataaga aattcaaaaa caagattgat gaaggcaata gaggaaatta
     2101 cctttgaaga tgcagaagat gctgatataa aaagagaaaa tgcaaatatt aatggtaata
     2161 cagcaatggg aactatgtta caatatggaa gcactgtatc taaagaattt tgtaaaacac
     2221 atatattaaa accagagcat tcttttgctc atgataatgg agatatacac atacatgata
     2281 tggatttttt aaatatggga acattaactt gttgtcaaat agatgttaaa aaactattca
     2341 atggtggatt ttcaacagga catggctttt taagagagcc acaagatata ataagttatg
     2401 gtgcattagc tgcaattgct atacaaagca atcaaaacga tcaacatgga ggtcaaagta
     2461 taccattttt cgattatgga ttggctgaag gtgtatataa gacatttaag aaattctaca
     2521 taggaaattt agctaaagca ttgaagttat ttaaaggaat tgaaaataat gatgtgataa
     2581 agaacatagt atataataca gagaaagaaa caaatcaaaa agttggtctt aagagagatg
     2641 aattgtatct aaacttagaa aaagagaaat taatacagac ttttgatata gatgatgaac
     2701 ttgtaaataa gatgcaaaac tttgcatttg aagaatcgta tagagaaact gataaaaaaa
     2761 catatcaatc tatggaagca tttatacaca atctaaatac aatgcactct agagcaggtg
     2821 cacaggtacc attttcaagt gtaaacttcg gaacagatac ttctgaagaa ggaagaatgg
     2881 taactaagaa tcttctatta tctcaagaaa gaggtttagg taatggagag acaccaattt
     2941 ttccaatttt aatatttaag gtcaaagaag gcataaattt aaatcctgaa gaccctaatt
     3001 atgatttatt taaattatca tgcagagtat cagctaaaag actattccct aattttagct
     3061 ttttagatgc gccttttaat gcaaaatatt ataaaaaagg tgaaccagat acagaggcta
     3121 catatatggg ttgtagaaca agagtactta gtaatgtgtg tggttcagaa acagttagtg
     3181 gtagaggaaa catatctttt actacagtaa atttaccaag attgggtata aaacatggta
     3241 ttataaataa tgaaaaggct aatttagatg gtttctttga agaattagat gagaagataa
     3301 acttaattat agaacaatta ttggagcgcc ttgaggtaca aggaaataaa aagatgaaga
     3361 attttccatt cttaatgggg caaggtgtat ggaaaggttc tgatgattta ggaccagaag
     3421 atacactaaa agaagtaata aaacaaggaa cattgacaat tggatttata ggtttagcag
     3481 agtgccttat tgctcttata ggtaaacatc atggagaaag taaagaagct caagaattag
     3541 gattaaaaat agtgtcacat atgagacata aaatggatga agcaacggac aaatataaat
     3601 taaatttctc cttaatgggt actccagcag aaggtctttc aggtaggttt actaaaatag
     3661 ataaaaaagt ttatggagaa attaaaggta tcacagataa agaatattat actaattcat
     3721 tccatgtacc agtttattac aatataagtg catatgataa aattgagata gaagctccat
     3781 accatgaatt gactaatgca ggtcatataa catatgtaga gttagatgga gatccatctg
     3841 ataatttaga agcttttgaa actgttataa aagctatgaa agatttgggt ataggatatg
     3901 gaagtataaa tcatcctgta gatagagacc caatatgcgg tttttcaggt gtaataacaa
     3961 gtaatatatg ccctgtatgt ggaagaaatg aagatgaaag tgacatcaaa ttcgaaagaa
     4021 taagaagaat aacaggatac ttagttggta cagttgatag atttaataat gctaaaaaag
     4081 cagaagtaag agatagagta aaacatagat agttttattt gggggaataa gttatgaaaa
     4141 taagaatgtc atctactata agttatgaca gcatagttga tggaccagga ttaagaatgg
     4201 taatatggac tcaaggatgt attcataatt gtaaagagtg ccataatcct cagacacatg
     4261 atttatgtgg aggattttat atggatacag aagaaattat aaataaagtc aaatcattga
     4321 aattacaaaa aggcattacg ctatcaggag gagaaccatt tttacaacca gaaccattag
     4381 aagaaatagc aagagaagct aaaataaatg ggttagatgt atggtcatat actggattta
     4441 cgtttgaaca actgttagat aaaaaaaata gagcgtattt taaaaattta aatttactaa
     4501 agcaaattga tattttagtg gatggaaaat ttatagctga aaaaaaagat ataagcttaa
     4561 agtttagagg gtcatcaaat caaaggataa ttgatgttca aaaaagtttg aaatataaaa
     4621 aagtgttttt ggttgagcaa tatatgaagg atgatttatc tatagcagaa taaaatataa
     4681 ataaacagga ttaaatatat gcatatattt aatcctgttt attttcatat aatatttcaa
     4741 gcttgtataa tgtaacaatt aaaccaaaag actcattgta tatttgaaat taagtttttt
     4801 atagtttata ggtgttttat gtggattacg aatgatatag tattgataca ttatttaata
     4861 gattcttatg ccaagaaaca attaatttat agaaattctt aattgttaca atataaatat
     4921 ctagataagt tataagatac tgataaataa tttataaagt ttattaatct aatattgtgt
     4981 gtgaatatta agtggtcaag tagtctaaaa aatgaaaaag atttaaaaaa gtgttttaac
     5041 taaacacata agtgttaaat tcatgtataa gtataggtta gatacataag aaataattat
     5101 gtaatatcta tctttgtaaa aaaatattaa attttgtaat ttgtggataa atatgtttat
     5161 aatgtggata atatttaatg taataagtta aagcaatatg aatcaactgt ttataatgtg
     5221 gataatatta taaatgtatg aataattgca gtatttaaaa acaaaaaaag ttaaaaaagt
     5281 tgttgactct aaaagaaaaa gttggtatag taatacttgt cctcaagaaa agggcaaaca
     5341 aataaagcat aa
//
LOCUS       DAYAOO010000161         5341 bp    DNA     linear   BCT 12-OCT-2024
DEFINITION  TPA_asm: Clostridioides difficile isolate ST8-SSI-h139-18
            SAMN40601845-rid21577343.denovo.165, whole genome shotgun sequence.
ACCESSION   DAYAOO010000161 DAYAOO010000000
VERSION     DAYAOO010000161.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN40601845
            Sequence Read Archive: SRR28438827
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 5341)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5341)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-MAY-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-MAY-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002157583.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002157583.1
            Genome Coverage       :: 163x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/11/2024 16:19:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 4,038
            CDSs (total)                      :: 3,963
            Genes (coding)                    :: 3,930
            CDSs (with protein)               :: 3,930
            Genes (RNA)                       :: 75
            rRNAs                             :: 6, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 60
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 33
            CDSs (without protein)            :: 33
            Pseudo Genes (ambiguous residues) :: 0 of 33
            Pseudo Genes (frameshifted)       :: 7 of 33
            Pseudo Genes (incomplete)         :: 25 of 33
            Pseudo Genes (internal stop)      :: 11 of 33
            Pseudo Genes (multiple problems)  :: 8 of 33
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5341
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN40601845-rid21577343.denovo.165"
                     /isolate="ST8-SSI-h139-18"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Denmark"
                     /collection_date="2018"
                     /collected_by="Statens Serum Institute"
     gene            <1..832
                     /gene="bclA3"
                     /locus_tag="ACGI5H_003807"
     CDS             <1..832
                     /gene="bclA3"
                     /locus_tag="ACGI5H_003807"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891815.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="collagen-like exosporium glycoprotein BclA3"
                     /protein_id="HFG9699480.1"
                     /translation="TGNTGADGATGPTGATGPTGADGLVGPTGATGATGLAGATGATG
                     PIGATGPTGADGATGATGATGPTGADGLVGPTGATGATGATGATGPTGATGATGATGP
                     TGASAIIPFASGIPLSLTTIAGGLVGTPGFVGFGSSAPGLSIVGGVIDLTNAAGTLTN
                     FAFSMPRAGTITSISAYFSTTAALSLVGSTVTITATLYQSTAPNNSFTAVPGATVTLA
                     PPLTGILSVGSISSGIVTGLNIAATAETRFLLVFTATASGLSLVNTVAGYASAGIAIN
                     "
     gene            1001..1762
                     /locus_tag="ACGI5H_003808"
     CDS             1001..1762
                     /locus_tag="ACGI5H_003808"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429711.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="epoxyqueuosine reductase"
                     /protein_id="HFG9699481.1"
                     /translation="MKNKIEISMNNFVKNYHKSNNITTKWQELLFAYASAEDDMFQKL
                     KSVVGTSHAMPKDFLENGKTIITYFIPFDESVNNSNIGGFECSEIWARAYIETNMLIS
                     NLNDFLCEELEKMGANSYAIPGSYNFDSEKLVSDWSQRHVAFIAGLGTFGLNNMLITE
                     KGCCGRIGSIITSLELEPTKRPENEYCLYKHNNSCKKCVNKCVKEALKEDGFNRNKCY
                     EMCMINEKKYTYIGGCDICGKCIVGVPCSVINPSR"
     gene            2071..2349
                     /locus_tag="ACGI5H_003809"
     CDS             2071..2349
                     /locus_tag="ACGI5H_003809"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429712.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CD3324 family protein"
                     /protein_id="HFG9699482.1"
                     /translation="MSYKKAIHILPEELLELIQEYVDGECIYIPRKSNNKKEWGSNTP
                     TREELSIRNMQIYEDYQVGYDLQYLSEKYYLSLKSIQRIVLQEKRKDI"
     gene            2642..3217
                     /locus_tag="ACGI5H_003810"
     CDS             2642..3217
                     /locus_tag="ACGI5H_003810"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891809.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1062 domain-containing protein"
                     /protein_id="HFG9699483.1"
                     /translation="MKKITWEVEYISQLPVIRYCKKCGKKTEYICSGLFRVNAQHKYL
                     DIWLIYKCSNCDSTWNSTIYSRVNPKSLNPEILEQFHTNDYNLVKQYAMNMELLHRNG
                     AEVGIPEYKIVGQEININDLTQVHIISKYPCQLKVSTLLREKLGLSRKVFDEMLDCGI
                     IRSNSGVDLKKGKLNYEIMLDIGKEKQKSSN"
     gene            3656..4366
                     /locus_tag="ACGI5H_003811"
     CDS             3656..4366
                     /locus_tag="ACGI5H_003811"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437285.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LytR/AlgR family response regulator
                     transcription factor"
                     /protein_id="HFG9699484.1"
                     /translation="MINIGICDDELHYRIKIKDILSEILSSYPINYNIYEFSAGEELL
                     NNYPKDLDILIMDIQMKTINGMDTARKIREFDHKLEIIFVTSFVEFMQEGYEVKAYRY
                     ILKPINKEKISKSVLPCINEMMKKRNNYLTINVKNYVDRIKIDSITYIETDRPNILIY
                     THDDMYITKMSISKIEKILNEYGFFRCHNSYIVNLKLVESMSGSTVIVDGKSIPISKY
                     RVKGLKLAITNILGDIVC"
     gene            4360..>5341
                     /locus_tag="ACGI5H_003812"
     CDS             4360..>5341
                     /locus_tag="ACGI5H_003812"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893947.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HFG9699485.1"
                     /translation="MLTNLSVGFWNIINLVSGTIDWIIFFLVIHLVGKRKISNIRYIF
                     TTIIIIIFMAYINVVKVFPNIKILLCMVIGISFYITSYEDKIYKSIIVSLLFWLGLMV
                     AEGSAVGLVVFINKLNNINITQHENLFRIQAIIMSKVFLFIGFILFKYFKLSLDFKPK
                     DMILIGIPILSNIVSLLLIFEYNLRVNTITTENLFIFIFAILLILSSSIILLIVIGKI
                     VQDDKLNLEYELINERIKTNYRNYENINEVHDRLKYVYHDLKNHMICIKNYDTKEEII
                     SYINNLEFQISEFEHFKNTGNKTLDLILAEKISICKKYDIQIEDNINISKL"
BASE COUNT         2154 a          571 c          897 g         1719 t
ORIGIN      
        1 aacaggaaat acaggagcag atggagcaac aggtccaaca ggggcaacag gtccaacagg
       61 agcagacgga ttagtaggtc caacaggagc aacaggagca acaggattag caggagcaac
      121 aggagcaaca ggcccaatag gagcaacagg tccaacagga gcagatggag caacaggggc
      181 aacaggagca acaggtccaa caggggcaga tggattagta ggtccaacag gagcaaccgg
      241 agcaaccgga gcgaccggag caacaggtcc aacaggagca acaggagcaa caggagcaac
      301 aggtccaaca ggtgctagtg caataatacc ttttgcatca ggtataccac tatcacttac
      361 aactatagct ggaggattag taggtacacc aggttttgtt ggctttggta gttcagctcc
      421 aggattaagt atagttggtg gagtaataga ccttacaaac gcagcaggaa cattgactaa
      481 ctttgcattt tcaatgccaa gagctggaac aataacatct atttcagcat acttcagtac
      541 aacagcagca ctttcacttg ttggctcaac agttacaatt acagcaacac tttaccaatc
      601 tactgcacca aataactcat ttacagctgt accaggagcg acagttacac tagctccacc
      661 acttacagga atattatcag ttggttcaat ttctagtgga attgtaacag gattaaatat
      721 agcagcaaca gcagaaactc gattcttact agtatttact gcaacagctt caggtctttc
      781 attagttaat actgtagcag gatatgcaag tgcaggaatt gcaataaatt agattagata
      841 agaaaaggct tctaatatcg tattgatatt aggagctttt ttaagaatga ttgatgaaca
      901 tagttttaat attaattagt gcgcatatta taaaatacta ttatataata taaaataata
      961 acattaaatt ggaaatatag aattatctag gggtgatact atgaaaaata agattgaaat
     1021 atcaatgaac aactttgtaa aaaattatca taaatcaaat aatataacta caaagtggca
     1081 agaacttttg tttgcttatg catctgctga agatgatatg tttcagaagc taaaaagtgt
     1141 tgtaggaaca tctcatgcta tgccaaaaga ttttctggaa aatggaaaaa ctataattac
     1201 atattttata ccttttgatg aaagtgtaaa taatagtaat attggagggt ttgaatgttc
     1261 tgaaatatgg gcaagagcgt acatagaaac taatatgttg atttcaaatt taaatgattt
     1321 cttatgtgaa gaactagaga agatgggggc taattcatat gctattcctg ggtcgtataa
     1381 ttttgacagt gaaaaattgg taagtgactg gtcacaaaga catgtagcat tcatagcagg
     1441 tcttggaact tttggtttaa ataatatgct tattacagaa aaagggtgtt gtggaagaat
     1501 aggaagcata atcacaagtt tagaattaga gccaactaaa agaccagaaa atgaatactg
     1561 cttgtataaa cataataata gttgcaaaaa atgtgtcaac aaatgcgtga aagaagcttt
     1621 aaaagaagat ggatttaata ggaataagtg ttatgaaatg tgtatgataa atgaaaaaaa
     1681 atacacttat ataggtggat gtgatatttg tggaaagtgt atagttggag ttccttgttc
     1741 agtaataaac ccatcaagat aatggattta agttgactaa taattttaaa gatagtttat
     1801 aatgaaaaaa ttttagttat caaaataaat ataatataaa aactaaataa atgtgtttaa
     1861 aaaatggata aataatttgt gttgattgac aaccagttat actgttgata gacttatatg
     1921 tatcgctgtg atatataagg agggttgaga ttttatgttt gatttaatct ttatttttgc
     1981 atagcaaggg ctattgcaac tatgaaattt aatatataaa tagccctttg ctattcctaa
     2041 tgaaaaatta ctatttaata ggagagcaaa atgagctata aaaaagcaat acatatatta
     2101 ccagaagaat tacttgaatt aatacaggaa tatgtagatg gtgaatgtat ctatattcct
     2161 agaaaatcta ataataaaaa agaatgggga agtaatacac ctactcgtga ggagttgtca
     2221 attagaaata tgcagattta cgaagactat caagttggat atgatttgca atatttatcg
     2281 gaaaagtatt atttatcttt gaaaagtatc caaagaattg tattacaaga aaaaagaaaa
     2341 gatatctaag gatgagccag tatagtttta taattatact ggctcatttt cttttgataa
     2401 aagtgtttga ggtatagttt cttttaagtg gatgatataa tttaagtaat ttcaataact
     2461 tatacagtag ctaacaaagc tggttgtaaa gtatctaata agaagtagta gctttttata
     2521 tgtttgaaat taaaatttat taaaattagg aggtcttgtt ttgaaaaaaa tacttgatta
     2581 tattccacct tttcataact ttctattaat ttagtaatct tatagaaagg aaattgcatt
     2641 tatgaaaaaa attacttggg aggtggaata tatctcccag ttacctgtaa ttaggtattg
     2701 taaaaaatgt ggaaaaaaga ctgaatatat ttgttcaggt ttatttaggg ttaatgctca
     2761 acataaatat ttggatatat ggttaatata caagtgttca aattgtgatt caacatggaa
     2821 ctcaactata tattctcgtg ttaatccaaa aagcttaaat ccagaaatac tagaacaatt
     2881 ccatacaaac gattataatc ttgttaagca atatgctatg aatatggaac ttttacatag
     2941 aaatggagca gaagttggta ttccagagta taaaatagta ggacaagaaa ttaatattaa
     3001 tgaccttaca caagttcata ttattagtaa atatccatgt cagttaaagg tatcaacatt
     3061 attacgtgag aaactaggtt tatctaggaa ggtatttgac gaaatgttgg attgtgggat
     3121 tattagaagt aactcaggag ttgatttaaa gaaaggtaaa ttaaattatg aaattatgtt
     3181 agatataggc aaggagaagc aaaagtcttc aaattgatta gaataactaa cttaatatat
     3241 tttcaggaac atcatttaaa aaaatagtgg ctttaaaaaa tttaaagcca ctatttttta
     3301 atatgtttta tattaatatt taaaatatag tgtgtattct tcaaaattat agcgataatt
     3361 aaaatattac tataaaaagg aaggtgcata ctttttattt aacaaaaact agatattaaa
     3421 aacttttcga ggaatatttt attaaaatcc ctaaatatat ttaatatata ttaaaaaatt
     3481 gtattataat gaaaatcaaa atagattgca aatccaaaaa gtaatactta atgtccaaaa
     3541 agctaaaatt aaaatctaaa tagctattta ctacagaagt atgttaaaat atgtaaaatg
     3601 aatagaaatt tatatatttt tattaaaaat atataagaaa ggatgtttaa gaattgtgat
     3661 taatatagga atatgtgatg atgaactaca ttatcgaata aaaataaaag atatattaag
     3721 tgaaatatta agttcatatc ctataaatta taacatatat gaattttcag caggagaaga
     3781 gttactaaat aactatccta aagatttaga catattaatt atggacatac aaatgaaaac
     3841 aataaatggt atggatactg ctaggaagat aagagagttt gatcataagt tagaaataat
     3901 atttgttact tcatttgtag agtttatgca agaaggttat gaggtaaaag catacagata
     3961 tatactaaag ccaataaata aagaaaaaat ttctaaaagt gtattacctt gtataaatga
     4021 gatgatgaaa aagagaaata attacttaac tataaatgta aaaaattatg tagaccgaat
     4081 taaaatagat tctattactt atatagaaac agatagaccg aatatattga tttatacaca
     4141 tgatgatatg tatattacta aaatgagtat atctaaaata gaaaagatat taaatgaata
     4201 tggatttttt agatgtcata atagctatat agttaactta aaattagtag aatcaatgag
     4261 tggaagtact gttatagtag atggaaaaag tattccaata agtaaatata gggttaaagg
     4321 cttgaagctt gcgataacta atatattagg ggacatagta tgctaacaaa tttaagtgta
     4381 ggattttgga atattattaa tttagtttca ggtactatag attggattat atttttttta
     4441 gtaatccact tagttggaaa gaggaaaata tctaatataa gatatatatt tacaacaata
     4501 attataatta tatttatggc atacataaat gtagttaaag tgtttccaaa tattaagatt
     4561 cttctatgta tggtaatagg aatatcattt tatataacat catatgaaga taaaatctat
     4621 aaaagtataa tagttagttt attgttttgg ctaggattaa tggttgctga aggttctgca
     4681 gtaggtctag tagtatttat aaataaatta aataatatta acataacaca acatgaaaac
     4741 ttatttagaa tacaagctat tattatgtca aaggtatttt tatttatagg ttttatattg
     4801 tttaagtatt ttaaattatc tttagatttt aaacctaaag atatgatact aataggaata
     4861 cctatattat ctaatatagt tagcttatta cttatatttg aatataattt aagagtcaat
     4921 acaattacta cagaaaactt atttatattt atatttgcaa ttttattgat tttatcatca
     4981 agtataatac ttttaatagt aatagggaaa attgtacaag acgataaatt aaatctagag
     5041 tatgaactta taaatgaaag aataaaaaca aactacagga attatgaaaa tataaacgaa
     5101 gttcatgata gattaaaata tgtttatcat gacttgaaaa accatatgat ttgtataaaa
     5161 aattatgaca ctaaagaaga aattatatca tatataaata acttagagtt tcagataagt
     5221 gaatttgaac attttaaaaa tactggaaat aaaacattag atttaatttt agcagaaaaa
     5281 ataagtattt gtaaaaagta tgatattcaa attgaagata acataaatat atctaaatta
     5341 a
//
LOCUS       DAYAOO010000162         5302 bp    DNA     linear   BCT 12-OCT-2024
DEFINITION  TPA_asm: Clostridioides difficile isolate ST8-SSI-h139-18
            SAMN40601845-rid21577343.denovo.166, whole genome shotgun sequence.
ACCESSION   DAYAOO010000162 DAYAOO010000000
VERSION     DAYAOO010000162.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN40601845
            Sequence Read Archive: SRR28438827
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 5302)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5302)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-MAY-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-MAY-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002157583.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002157583.1
            Genome Coverage       :: 163x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/11/2024 16:19:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 4,038
            CDSs (total)                      :: 3,963
            Genes (coding)                    :: 3,930
            CDSs (with protein)               :: 3,930
            Genes (RNA)                       :: 75
            rRNAs                             :: 6, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 60
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 33
            CDSs (without protein)            :: 33
            Pseudo Genes (ambiguous residues) :: 0 of 33
            Pseudo Genes (frameshifted)       :: 7 of 33
            Pseudo Genes (incomplete)         :: 25 of 33
            Pseudo Genes (internal stop)      :: 11 of 33
            Pseudo Genes (multiple problems)  :: 8 of 33
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5302
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN40601845-rid21577343.denovo.166"
                     /isolate="ST8-SSI-h139-18"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Denmark"
                     /collection_date="2018"
                     /collected_by="Statens Serum Institute"
     gene            123..959
                     /locus_tag="ACGI5H_003813"
     CDS             123..959
                     /locus_tag="ACGI5H_003813"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891338.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HFG9699486.1"
                     /translation="MNIKKIFNNNVVVSSLEDGTEIIVTGAGVGFKKKVGDLIDENLI
                     SKKYFVQDDQRDKYNQILNKTSIEYFKISEEIIEKANEVLNTQVNDSIILALTSHIEF
                     AVQREKQGIKLPNLILNETKQLYREEFEFGLWAIDEIEKRIGIKLPEDEAGYIAIHII
                     NGLENSQKDEGINILEFSKQVIQIIEEVHGFKLDVNSLNYTRLITHLKFFVQRILRKE
                     TYNDSDIEDMYKLVNKNYNKPKVCTEEIAALVLDRFEYKISKEEELYLMIHINKITNS
                     GC"
     gene            1312..2889
                     /locus_tag="ACGI5H_003814"
     CDS             1312..2889
                     /locus_tag="ACGI5H_003814"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439882.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HFG9699487.1"
                     /translation="MKKNKLGLWNFFQMLGKTFMFPIALLSVSGMMLGLGAGFTDPKM
                     IEMVPFLGNEYVNLVLNFMLTIGLFAFNNLGALFAMAIPLGLLKKEKEFGAFSGLVGF
                     IAMHIGTNFYLTRADLLVPAEQMSTNGQAMIMGIQTYNTSVLGGIVAGLIVYAIYDKV
                     SNLKIPESLGFYSGPRLVPIVSLIVMSIVGLLIPIVWPPFFNAFQSLGRWISSAGPLG
                     YFSYAVAERVTIPFGLNHLVTSVFRFTPIGGTAVIDGETYFGTLNMFMAYVENNQIIP
                     LDLAGKMEQGKLMIQYGLAGAALAIYRTAKPENRKALKGLLISGVLTVIIGGISEPIE
                     FLFLFISPALFAFHTFMNGLANMVLPYLGVLMGFTGDLIAFISFGVLRGTATGWPIAV
                     LVAVLYFAIYYFVFKWAIIKFNIKTPGREDKEIKVSEGNGSNFKNLSTYKGQQMISAL
                     GGQSNILSLDNCVTRLRLKLQDVSLINEDAIKEAGGIAVVKLDEHTIQVIIGTQVYSL
                     RKQMDKAMEGHLEACND"
     gene            2882..4066
                     /locus_tag="ACGI5H_003815"
     CDS             2882..4066
                     /locus_tag="ACGI5H_003815"
                     /EC_number="4.4.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439880.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA];
                     GO_function: GO:0047804 - cysteine-S-conjugate beta-lyase
                     activity [Evidence IEA];
                     GO_process: GO:0009086 - methionine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MalY/PatB family protein"
                     /protein_id="HFG9699488.1"
                     /translation="MINFDKKVDRLGTYCTQWDYVEDRFGKKDLLPFTISDMDLEFPF
                     EITEVLQERLNHRVLGYSRWKHDDFRNSVTNWYIKRFNCSVDSNWIYYSPSVMYSISK
                     LIEMLSNEGDGILINTPAYNAFYDVIINNNRNIIKSHLVNRNGFYSIDFNDFEKKCKK
                     SKIFILCNPHNPTGRVWSELELVKMIGICKNNDVKIISDDIHMDIVYDNRMTPILNVA
                     KDYLDSVFICTSASKSFNIPALTGSYVIIPNEGIRNKFENITRYRDFVNSPAILAILA
                     TMVCYDDCEYWLDELLKYLKENLKYTIDYIKDNLEPLKLVMPEGCYFAWIDFSELKIS
                     GEKFQKLLMDIGEVAIMSGSVYGEEGEFYLRLNVACSREKLEDGLNRIKKTMDYIEKR
                     IL"
     gene            4084..4683
                     /locus_tag="ACGI5H_003816"
     CDS             4084..4683
                     /locus_tag="ACGI5H_003816"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903412.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SIS domain-containing protein"
                     /protein_id="HFG9699489.1"
                     /translation="MGYLKTMVDVMTTEMNAIRCLIDEAGIEYESIVSEIANCEGKVI
                     FMGVGKSAHIGKKLAATFASTGTPSFFVHATEAVHGDLGMIESKDITILISNSGNSME
                     VVNCIKYIKAIGSKTIAFTSNRNSVLAKECDYALIYPAKDEADHLNLAPTTSSTITLV
                     LGDSIACALSKSSNFGSSDFYKYHPGGSLGEKLKTANNG"
     gene            4707..5177
                     /locus_tag="ACGI5H_003817"
     CDS             4707..5177
                     /locus_tag="ACGI5H_003817"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439878.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucose transporter subunit IIA"
                     /protein_id="HFG9699490.1"
                     /translation="MFKMFKKKSIKSPISGKVIELSKIQDGVFSQKIMGEGVAIDSTG
                     DIVYAPINGKIVVVAETKHAFVIELENGMELLIHVGLDTVNLKGEGFEALVSMGEQVK
                     EGTPMLKINRPLIESKGISLITPVTITNHSEYNMNTCNVGNSVEGGKDTVIEFK"
BASE COUNT         1979 a          560 c         1021 g         1742 t
ORIGIN      
        1 ttgtagtatt atagggtaaa ttgcaaaata tatacgaaag taaaatttta aatattgaca
       61 ttaaattaaa tatactatac tatgtaagtg tgatgagaga atttttttag aggggattta
      121 tagtgaatat aaaaaagata tttaataaca atgtagtagt aagctcccta gaagatggca
      181 cagaaataat tgtcactggt gctggagtag gatttaagaa aaaagtaggc gatttgatag
      241 atgaaaattt gatttctaag aaatattttg ttcaagacga tcaaagggac aaatacaatc
      301 aaatacttaa taagacctct attgaatact ttaaaatttc agaagaaatt atagaaaagg
      361 ctaatgaagt tttaaatact caagtgaatg attcaataat attagcctta actagtcaca
      421 tagaatttgc tgtccaaaga gaaaaacaag gtataaaatt accaaactta atattgaatg
      481 agacaaaaca actttatagg gaagaatttg aatttggatt atgggcaatt gatgaaattg
      541 aaaaaaggat aggaataaaa ttgcctgaag atgaagcagg atatattgct attcacataa
      601 tcaatggttt ggaaaattct caaaaagatg aaggtattaa tatactagag ttttcaaaac
      661 aagttattca gataattgaa gaagtacatg gatttaaatt ggatgtaaat tcattaaatt
      721 atactagact tataactcac ttaaagtttt ttgttcaaag gattctccga aaagaaactt
      781 acaatgatag tgatattgaa gatatgtata agttagtgaa taaaaattac aataaaccta
      841 aagtgtgtac tgaagaaatt gcagcattgg tattagacag atttgaatat aagattagta
      901 aagaagaaga attatattta atgattcaca taaataaaat aacaaacagt ggttgttagg
      961 attgtaactg ataaagcagg caaaacctaa gtcattgagc ttaactatta gattaagttt
     1021 tttgatttag gtttttttat tagatacaat caaaatacag acagtgactt ttaggattgt
     1081 aactggttaa gcaggcaaaa cctaaatcat tgaatttaac tattaggtta agttttttga
     1141 tttaggtttt tttattagat acaatcaaat acagacagtg gttgttagga ttgtaactgg
     1201 ttgagcaggc aaaacctaaa tcattaaact taattattaa attaagtttt ttgatttagg
     1261 tttttctata aatttgatta tgtttttaga taaaaatagg aggggaaaat tatgaaaaaa
     1321 aataagttag gtttatggaa cttcttccaa atgttaggaa aaacgtttat gttcccaata
     1381 gcactactta gtgtttctgg gatgatgcta ggacttgggg caggttttac agaccctaag
     1441 atgattgaaa tggttccatt tttagggaat gaatatgtta acttagtttt aaacttcatg
     1501 ttaacaatag gattatttgc atttaacaac ttgggagcat tatttgcaat ggcaattcca
     1561 ctaggattat taaaaaaaga aaaagagttt ggtgcttttt caggattagt aggatttata
     1621 gcaatgcata taggtacaaa tttttattta acaagagctg atttgttagt accagcagaa
     1681 cagatgtcaa ctaatggtca agctatgatt atgggtatac aaacatataa tacaagtgtt
     1741 ttaggtggta ttgtagcagg attaattgtt tatgcaatat atgataaagt tagtaattta
     1801 aagataccag aatcattagg attctacagt ggaccaagat tagttccaat tgttagttta
     1861 atagttatga gtatagttgg attattaata cctattgttt ggccaccatt tttcaatgca
     1921 ttccaaagtt taggaagatg gatttcttca gcaggaccat taggatattt ttcatatgca
     1981 gtggcagaaa gagttacaat tccatttgga ctaaatcatc ttgtaacatc tgtattccgt
     2041 tttacaccaa taggtggaac tgctgttatt gatggagaaa cgtactttgg tacattgaac
     2101 atgtttatgg catatgtaga aaataatcag attatacctc ttgatttagc tggtaaaatg
     2161 gaacaaggta aattgatgat tcaatatgga ttagctggtg ctgcattggc tatctaccgt
     2221 acagcaaaac cagaaaatag aaaggcactt aaaggacttt taatatcagg agtgttgaca
     2281 gttattatag gtggtataag tgaaccaata gagtttctat tcttattcat atcaccagca
     2341 ttatttgctt tccatacatt tatgaatggt ctagcaaaca tggtacttcc atacttaggc
     2401 gtgttgatgg gattcacagg agatttaatt gcatttataa gttttggtgt gttaagagga
     2461 acagctacag gatggccaat agcagtatta gtagcagttt tatattttgc aatatactat
     2521 tttgtattta agtgggcaat tattaagttt aatataaaga ccccaggacg tgaggataaa
     2581 gaaataaaag tatctgaagg aaatggttca aatttcaaaa atttgtctac atataaagga
     2641 caacaaatga tatctgcttt aggtggtcaa tctaatatat tatcactaga taattgtgta
     2701 actagattac gtttaaaatt acaagatgta tcattaataa atgaggatgc aattaaagag
     2761 gctggtggta tagcagttgt taaattggat gagcatacaa tacaagtaat tataggaacc
     2821 caagtgtatt ctttaagaaa gcagatggat aaagctatgg aaggtcattt ggaggcatgt
     2881 aatgattaat tttgataaaa aagtagaccg attgggtaca tattgtaccc agtgggacta
     2941 tgtagaagat agatttggta agaaggattt gcttcctttt acaatttcag atatggattt
     3001 agagtttcca tttgaaataa cagaggtgtt gcaggaaagg ttaaatcata gagttttggg
     3061 atacagtaga tggaaacatg atgattttag aaattcagtt acgaattggt atattaaaag
     3121 atttaattgt agcgttgata gtaactggat atattatagt ccaagtgtaa tgtattcaat
     3181 tagcaaactt attgagatgt taagtaatga aggagatgga atccttataa atactcctgc
     3241 atacaatgct ttttatgatg tgataataaa taacaatcgt aatattataa agtcacatct
     3301 tgtaaatagg aatggattct attcaattga ttttaatgat tttgagaaaa agtgtaaaaa
     3361 atctaagata tttattttat gtaatcctca caatccaact ggtagagtat ggagtgagtt
     3421 agaacttgtt aagatgatag gaatttgtaa gaataatgat gtcaagataa tatcagatga
     3481 tatacacatg gatattgtat atgacaatag aatgacacct atcttaaatg ttgcaaagga
     3541 ctatttagat tctgtattca tttgtacatc agcgtctaaa tctttcaata taccagcatt
     3601 gactgggtca tatgtgatta taccaaatga aggtattaga aataaatttg aaaatatcac
     3661 tagataccgt gattttgtaa attcgccagc aattctagca atattagcca caatggtctg
     3721 ttatgatgac tgcgaatatt ggttagatga actattaaaa taccttaaag agaatcttaa
     3781 atatacgatt gattatataa aagataattt agaaccattg aaattggtca tgccagaagg
     3841 ctgttacttt gcttggatag atttttccga acttaaaata agtggtgaga aattccaaaa
     3901 attattgatg gatattggag aagttgctat tatgtcgggg tctgtatatg gtgaagaagg
     3961 tgagttttat ttaaggttaa atgtggcatg ttcaagagaa aaacttgaag atggtttaaa
     4021 taggattaaa aaaactatgg attatattga aaaaagaatt ttatagtagg aagggagata
     4081 gttatgggat atttaaaaac aatggttgat gttatgacta ctgaaatgaa tgccataaga
     4141 tgtttaatag atgaagcagg aatagaatat gaaagtatag ttagtgaaat tgcaaattgt
     4201 gaaggcaaag taatttttat gggtgtagga aaatctgcac atataggtaa gaaattggca
     4261 gctacatttg ctagtactgg tacacctagc ttttttgtac atgcaacaga ggcagtgcat
     4321 ggagatttag gaatgattga aagtaaggat attacaattt taatatcaaa tagtggaaat
     4381 tctatggaag tggtaaactg tataaaatat attaaagcaa taggttctaa gacaattgca
     4441 tttacttcaa acagaaattc agtactggca aaagagtgtg attatgcttt aatatatcct
     4501 gcaaaggatg aagcagacca tttaaatcta gcaccaacaa catcatctac aattactttg
     4561 gttttaggag attctattgc atgtgcatta tctaagagta gtaattttgg ttcttcagat
     4621 ttttataagt accatccagg aggaagttta ggtgagaagt taaaaacagc taacaatgga
     4681 taaaagcaaa aaggagagta gtttttatgt tcaaaatgtt taaaaaaaaa tcaataaaat
     4741 cacccatatc aggaaaagta atagagttat ctaaaataca agatggtgta ttttctcaaa
     4801 aaattatggg agagggtgta gctatagatt ctacaggaga cattgtatat gctccaatca
     4861 atggaaagat agtagtagta gcagagacta aacatgcatt tgtaatagaa ttagaaaatg
     4921 gaatggaact tcttattcat gttggtttag atactgtaaa tttaaaaggc gaaggttttg
     4981 aggcattggt gagtatggga gaacaagtga aggaaggaac accaatgttg aaaattaacc
     5041 gtcctttgat tgaatcaaag ggtatatcac ttattactcc agttacaata actaatcatt
     5101 cagagtacaa tatgaataca tgtaatgtag gcaatagtgt tgaaggtggg aaagatactg
     5161 taattgagtt taaataaaga actaaaatac aaggttaata tttataaata cctataaact
     5221 tatgttttat aagattgatt gtatagattt gttgtataaa aaagaactct ttaattataa
     5281 attaaggagt tcttttttat tt
//
LOCUS       DAYAOO010000163         5110 bp    DNA     linear   BCT 12-OCT-2024
DEFINITION  TPA_asm: Clostridioides difficile isolate ST8-SSI-h139-18
            SAMN40601845-rid21577343.denovo.167, whole genome shotgun sequence.
ACCESSION   DAYAOO010000163 DAYAOO010000000
VERSION     DAYAOO010000163.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN40601845
            Sequence Read Archive: SRR28438827
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 5110)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5110)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-MAY-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-MAY-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002157583.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002157583.1
            Genome Coverage       :: 163x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/11/2024 16:19:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 4,038
            CDSs (total)                      :: 3,963
            Genes (coding)                    :: 3,930
            CDSs (with protein)               :: 3,930
            Genes (RNA)                       :: 75
            rRNAs                             :: 6, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 60
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 33
            CDSs (without protein)            :: 33
            Pseudo Genes (ambiguous residues) :: 0 of 33
            Pseudo Genes (frameshifted)       :: 7 of 33
            Pseudo Genes (incomplete)         :: 25 of 33
            Pseudo Genes (internal stop)      :: 11 of 33
            Pseudo Genes (multiple problems)  :: 8 of 33
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5110
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN40601845-rid21577343.denovo.167"
                     /isolate="ST8-SSI-h139-18"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Denmark"
                     /collection_date="2018"
                     /collected_by="Statens Serum Institute"
     gene            complement(554..2689)
                     /gene="rnr"
                     /locus_tag="ACGI5H_003818"
     CDS             complement(554..2689)
                     /gene="rnr"
                     /locus_tag="ACGI5H_003818"
                     /EC_number="3.1.13.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429582.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0004518 - nuclease activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease R"
                     /protein_id="HFG9699491.1"
                     /translation="MIPGLKESLLGLINESAYNPLKKEELAEIFDIHSSEMPMFYNFL
                     NELEEDGYICFTKKGKIVSPNQMGYFVGKFVSHKKGFGFVESDVEYTQDLFISSDNIN
                     GAMHNDRVMAEIVVPATEEKRAEGRIVKVIKREITRIVGTFQSSKTFGFVTPDNKKFT
                     KDIYIPKKHFSGAVDNDKVVCEITVWPQEDRKPEGKIIEILGQKGERGVEIDSIIREH
                     GLPEEFPKKVLQEAEAVAVEIPQEEIKRRRDLRDLNIFTIDGDDAKDLDDAISIEVLP
                     NGNFKLGVHIADVTHYVREKNKLDKEALKRATSVYLVDKVIPMLPKTLSNGVCSLNPF
                     EDKLTLSIFMEIDHKGNVVKHEICESVINSKARMTYTEVSDILEKDDEKLKKTFEHVV
                     EDFKNAEILARILMSRREKRGAIDFNFPEAKIILNGKGEVVDIKPYERRISNKIIEEF
                     MLISNETIAEHFYWMGIPFVYRIHETPSLEKMEELSKFISTFGYIIKGDKEEVHPKAL
                     QGIIEKIKGKKEEGAISTIMLRSLKQAKYSPECSGHFGLAAKFYCHFTSPIRRYPDLQ
                     IHRIIKESLNNKISGKRQEQLTTIVDYASVQSSEKERKAELAERDVHDFYKALYMKDK
                     VGQEFEGVVSSVTSFGIFVELDNTIEGLIRLANMNDDYYIYDESSYSVLGERTKKSYK
                     IGDLVKIKVESVNVDFKEIDFEIVEKIEE"
     gene            3282..3896
                     /locus_tag="ACGI5H_003819"
     CDS             3282..3896
                     /locus_tag="ACGI5H_003819"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HEAT repeat domain-containing protein"
                     /protein_id="HFG9699492.1"
                     /translation="MEEVIAKIITIENGFKEIENIAKKIVKNNDSKKCYYLSIYLYRS
                     EYYQVRELAVFILGFISVTISEALLFLKDNVSKDENWRVQEILAKSFDYYCSEVGYEK
                     ALPVIKEWLNSDSPNIKRAVTEGLRIWTSRDYFKSNPDVAISLLSSLKEDDSEYLRKS
                     VGNALRDISKKYPDLVKKELDSWDISNKKVEFVYKLASKCILAK"
     gene            3914..4276
                     /locus_tag="ACGI5H_003820"
     CDS             3914..4276
                     /locus_tag="ACGI5H_003820"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="winged helix-turn-helix transcriptional
                     regulator"
                     /protein_id="HFG9699493.1"
                     /translation="MKLRDEYTCPLELTHDMIKGKWKSIILWRLRIGPTSLSKLEKEI
                     NGINQKMLLEQLKELIEFGLVDKKTYEGYPLKVEYSLTPIRGKQILDALAIMQDIGIS
                     FMLDNGMEDILKEKGVLK"
     gene            4382..4879
                     /locus_tag="ACGI5H_003821"
     CDS             4382..4879
                     /locus_tag="ACGI5H_003821"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421940.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YbhB/YbcL family Raf kinase inhibitor-like
                     protein"
                     /protein_id="HFG9699494.1"
                     /translation="MKVTSTGIVNGVIEDKYGKRGTQFNEGGMPTYSLPLKFEDAPKN
                     TVSFAVFLEDKDSVPVCGFAWIHWLAVNITKDELNENESVTATDFVQGTTSWHGKLGG
                     LDRLEASVYGGMAPPDRPHVYEIHVFALDTILDLEKGFYMNEFFKAIEGHVLDTFTLK
                     GSYSN"
BASE COUNT         1681 a          759 c          617 g         2053 t
ORIGIN      
        1 aaattctaaa aaagaaaagt tatcttaaat aaaaaataag tgtatcttaa attttaaatg
       61 atacacttat ttttatattg aaattatatt ttttaatatc tattcttaat taggtatttt
      121 taaattatct gtttacatta aatatttctt aattacttat ctttcagcta gctttttcta
      181 ttaaatgttt ctcaattact tatttttcaa ttagccactt atattaagca tttcttaatt
      241 acttattttt caattagcca cttatattaa acatttctta attatttatt tttcagttgg
      301 ctttttctat taaatgtttc ttaattactt atctttcagt tagctctttc tattaaacat
      361 ttctcaatta cttatttttc aattagctac tttcattaaa tatttcttaa ttatttatct
      421 ttcagttaac tatttccatt agatatttct caattaccta tttttatcat ttattttata
      481 gagtattgtg cactatatat ttatacatat cataaatact acaacttgtt atctcttatt
      541 ttagctgttt tatctactcc tctatttttt caactatctc aaagtcaatt tctttaaaat
      601 ctacattaac actttcaacc tttatcttaa caaggtctcc tatcttatat gacttcttag
      661 ttctttctcc taaaacacta taagaactct catcataaat atagtaatca tcattcatat
      721 ttgcaagtct tatcaatcct tctatggtat tatccaactc aacaaatatt ccaaatgaag
      781 ttacgctaga tacaacaccc tcaaattctt gaccaacttt atccttcata taaagagcct
      841 tatagaaatc atgtacatct ctttcagcta actctgcctt tctttctttc tcggatgatt
      901 gaacagatgc ataatccact atagtagtaa gctgttcttg tctttttcca cttattttat
      961 tatttaaaga ttcttttatt attctatgaa tttgaaggtc aggatatctt cttattggtg
     1021 aagtaaagtg acagtagaat ttagctgcta atccaaaatg tccactacat tctggtgagt
     1081 acttagcttg ttttaaagaa cgaagcatta tagtactgat agctccttct tcttttttgc
     1141 cctttatttt ctctattata ccttgtaatg cttttggatg tacttcctct ttatcacctt
     1201 ttattatata tccaaatgta gatataaact tactcaattc ttccattttt tccaaagatg
     1261 gtgtctcatg tattctatac acaaacggta ttcccatcca gtaaaaatgt tcggcaattg
     1321 tctcattact tataagcata aattcttcta ttatcttatt agatattctt ctttcatatg
     1381 gctttatatc tacaacttcg ccttttccat ttagaattat ctttgcctct gggaaattga
     1441 agtctatagc tcctcttttt tcccttcttg acataagaat cctagctaaa atttcagcat
     1501 ttttaaaatc ttcaacaaca tgttcaaaag tctttttaag tttttcatca tccttttcta
     1561 atatatcaga tacttctgta taagtcattc tagcttttga atttattaca gattcacata
     1621 tttcatgttt aaccacattt cctttatggt ctatttccat aaatatagaa agagttaatt
     1681 tatcttcaaa tggatttaag ctacatactc catttgaaag agtttttggc aacattggaa
     1741 ttactttatc tactaaataa actgatgtag ctctttttaa ggcttccttg tcaagtttat
     1801 ttttctctct tacataatgt gtaacatcag ctatgtgaac tcctagtttg aagtttccat
     1861 taggtaatac ttctattgat atggcatcat ctaagtcttt tgcgtcatct ccatctatag
     1921 taaatatgtt taaatctctt aaatctcttc ttctttttat ctcttcttga ggaatctcaa
     1981 cagctacagc ttctgcttct tgcaatactt tctttggaaa ttcttctgga agaccatgtt
     2041 ctcttattat agaatctatt tctacgcctc tttcaccttt ttgacctagt atctctataa
     2101 ttttgccttc tggttttcta tcctcttgtg gccatactgt aatttcacat actaccttat
     2161 cattatctac tgctccacta aaatgttttt taggtatata tatatcttta gtaaatttct
     2221 tgttgtctgg tgttacaaat ccaaaagttt tacttgattg gaaagtacct actattctag
     2281 ttatttctct ctttattact tttactattc ttccttctgc tctcttttct tcagttgcag
     2341 gtactactat ttctgccata actctatcat tatgcatagc accatttata ttgtcacttg
     2401 agataaataa atcctgtgta tattcaacat cagattctac aaatccaaaa ccctttttgt
     2461 gtgatacaaa ttttccaaca aagtatccca tttgattggg agatactatt tttccttttt
     2521 tagtaaagca gatataacca tcttcttcta attcatttaa aaaattataa aacattggca
     2581 tttctgatga atgtatatca aatatttctg ctaattcttc tttttttaga ggattatatg
     2641 cactttcatt tattaatcct agcaaacttt ctttaagtcc tggtatcatt tttccctcct
     2701 gttttacttt tcattatatt attatttata ttgtctttta tatttcttca gacaaaacat
     2761 tttttaatta tcacataatt ttctatattt tcttattatt ataagttaaa attacttatt
     2821 tatatttttg atttaatgta agctttgtca tactaacttc aaacaaatta tgatgtttta
     2881 taaattattt gtaaatatca ttataattac ttaagttatt ctttatcata attgcttaaa
     2941 ttactcttta tcacctaatt atacaccatc aaataggatt ggtaaaatat tcatctcata
     3001 taagtattac tatataataa tttattctat tagtatactc aaatcatgta aaatttatat
     3061 aactcaatta attttttaaa tacaacttta taatataaaa cttataataa aagtaaattt
     3121 atatgttaaa tgaggttgat tttttattat tttttattta tgctagtact aaagacttgc
     3181 aaacgttttt tgacaagtct ttattttgtc taaattaaac aaactttttt acaaataaat
     3241 acataaaatt taaactaatc tatttattgg aggagataaa attggaagaa gtaattgcaa
     3301 aaattattac tatagaaaat ggattcaaag aaattgaaaa cattgctaaa aaaattgtaa
     3361 aaaataatga ctcaaaaaag tgttattatc tatcaatcta cttatatagg tcagaatatt
     3421 atcaagtaag agaattggct gtgtttatac ttggttttat atcagtaact atttctgaag
     3481 ctttgttatt tttaaaagat aatgtgagta aagatgaaaa ctggagagta caagaaatac
     3541 tagctaaatc atttgattat tattgcagtg aagtaggata tgaaaaggct cttcctgtta
     3601 taaaagaatg gcttaattct gatagtccaa acataaaaag ggctgtgaca gaaggtcttc
     3661 gaatttggac tagtagagac tattttaaat ctaatcctga cgttgctata tcactacttt
     3721 ctagtttaaa agaagatgat agtgaatact tgagaaagtc tgtaggtaat gctcttagag
     3781 atataagtaa aaaatatcca gatttagtaa aaaaagaatt agattcatgg gatatatcaa
     3841 ataaaaaagt tgagtttgta tataagcttg cttcaaaatg tatcttggca aagtaaaatg
     3901 gaggtgaact tatttgaaac ttcgtgatga gtatacttgc ccattagaac taacacatga
     3961 tatgataaaa ggcaaatgga aatctattat attatggaga ttacgcatag gaccaacttc
     4021 cttatcaaaa cttgaaaagg aaatcaatgg tattaatcaa aagatgttac ttgaacaact
     4081 taaagaatta attgaatttg gtcttgtaga taaaaagaca tatgaaggtt acccacttaa
     4141 agttgaatac tcacttacac ctattcgagg gaaacaaata ttggatgctt tggctataat
     4201 gcaagatata ggaattagct ttatgttgga taatggtatg gaagatattc ttaaggaaaa
     4261 aggtgtttta aaataaatag atacccacaa aaaagtaagt aatttaccat tattttcaac
     4321 tggtatataa ttaaattata gatatattct attaatttat tataatagga ggtaaattat
     4381 tatgaaagta actagtacag gtatagtaaa tggtgttata gaagataaat acggtaaaag
     4441 aggaactcag ttcaatgaag gtggtatgcc tacatattca ctacctctaa agtttgaaga
     4501 tgctccaaag aatacagtat cctttgctgt atttttagaa gataaagact ctgttcctgt
     4561 atgtgggttt gcatggatac attggttagc tgtaaatata acaaaagatg agttaaatga
     4621 aaatgaaagt gtaacagcta ctgattttgt acaagggact actagttggc atggcaaact
     4681 aggaggtctt gacagattag aggccagtgt atatggtgga atggctcctc cagacagacc
     4741 tcatgtctat gaaatacatg tatttgcact tgatactatc cttgaccttg aaaaaggatt
     4801 ctatatgaat gaatttttca aagctattga agggcatgtt ttagatacat ttacactaaa
     4861 aggaagttat tctaattaat taggttgact atagctaatc attaattaaa tgctacattt
     4921 aattgatgat tagcttaatt gttattagaa tattttctgc actttatctt aatatatatt
     4981 ttagttgact ggtattttaa tttctattag attattatca atttatataa attgatttta
     5041 gcttaaaact tacttatcta tttcagtttc tattagaatt attattagac tcattaaaat
     5101 aaaagcacta
//
LOCUS       DAYAOO010000164         5015 bp    DNA     linear   BCT 12-OCT-2024
DEFINITION  TPA_asm: Clostridioides difficile isolate ST8-SSI-h139-18
            SAMN40601845-rid21577343.denovo.168, whole genome shotgun sequence.
ACCESSION   DAYAOO010000164 DAYAOO010000000
VERSION     DAYAOO010000164.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN40601845
            Sequence Read Archive: SRR28438827
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 5015)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5015)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-MAY-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-MAY-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002157583.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002157583.1
            Genome Coverage       :: 163x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/11/2024 16:19:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 4,038
            CDSs (total)                      :: 3,963
            Genes (coding)                    :: 3,930
            CDSs (with protein)               :: 3,930
            Genes (RNA)                       :: 75
            rRNAs                             :: 6, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 60
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 33
            CDSs (without protein)            :: 33
            Pseudo Genes (ambiguous residues) :: 0 of 33
            Pseudo Genes (frameshifted)       :: 7 of 33
            Pseudo Genes (incomplete)         :: 25 of 33
            Pseudo Genes (internal stop)      :: 11 of 33
            Pseudo Genes (multiple problems)  :: 8 of 33
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5015
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN40601845-rid21577343.denovo.168"
                     /isolate="ST8-SSI-h139-18"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Denmark"
                     /collection_date="2018"
                     /collected_by="Statens Serum Institute"
     gene            complement(28..228)
                     /locus_tag="ACGI5H_003822"
     CDS             complement(28..228)
                     /locus_tag="ACGI5H_003822"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011723062.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005829 - cytosol [Evidence IEA];
                     GO_function: GO:0001072 - transcription antitermination
                     factor activity, RNA binding [Evidence IEA];
                     GO_function: GO:0003676 - nucleic acid binding [Evidence
                     IEA];
                     GO_function: GO:0003723 - RNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cold-shock protein"
                     /protein_id="HFG9699495.1"
                     /translation="MNNGIVKWFNNEKGFGFISMESGDDVFAHFSAIQTSGFKSLEEG
                     QKVSFDIVKGARGPQAENITIL"
     gene            complement(453..629)
                     /locus_tag="ACGI5H_003823"
     CDS             complement(453..629)
                     /locus_tag="ACGI5H_003823"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9699496.1"
                     /translation="MFRDKMDKCTHMLTAYISNSYDYCDFIDTQLDDFILEYGEKVVE
                     SCLHQVMVLVSKYN"
     regulatory      complement(683..772)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF01051"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="cyclic di-GMP riboswitch class I; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /bound_moiety="cyclic di-GMP"
                     /db_xref="RFAM:RF01051"
     gene            complement(952..1152)
                     /locus_tag="ACGI5H_003824"
     CDS             complement(952..1152)
                     /locus_tag="ACGI5H_003824"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454608.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HFG9699497.1"
                     /translation="MPKFTCNLKKYRQLKELTQEQLAEKVGVRRETIMRLEAGKYNPS
                     LKLAIDISKIVDTPIDELFIFD"
     gene            complement(1154..1504)
                     /locus_tag="ACGI5H_003825"
     CDS             complement(1154..1504)
                     /locus_tag="ACGI5H_003825"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454606.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3796 domain-containing protein"
                     /protein_id="HFG9699498.1"
                     /translation="MIQKKFFMGFCGFLGFLSLRYFSSGNVADLTYIGFFAFFSNFII
                     AKINGDKADERYVQDEKAAMAFTGQLAIIELFILWCITIVSRNIELMCVLLSITYAIT
                     LNVYAIKLYILEEK"
     gene            1666..1854
                     /locus_tag="ACGI5H_003826"
     CDS             1666..1854
                     /locus_tag="ACGI5H_003826"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890498.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9699499.1"
                     /translation="MTKYDFNFKLKVAKFYLNREGRDILIVKQYGVYDHSQVERWVNI
                     LGESELKIKKFSILYGSS"
     gene            complement(2331..2531)
                     /locus_tag="ACGI5H_003827"
                     /pseudo
     CDS             complement(2331..2531)
                     /locus_tag="ACGI5H_003827"
                     /inference="COORDINATES: protein motif:HMM:TIGR04223.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(2890..3378)
                     /locus_tag="ACGI5H_003828"
     CDS             complement(2890..3378)
                     /locus_tag="ACGI5H_003828"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897487.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type II secretion system protein"
                     /protein_id="HFG9699500.1"
                     /translation="MKNKKGFTLVELLVVIAIIGILAIVALPALFKNIEKAKIAKLEA
                     DISAIKSASLSYYADESKYTEGNIIWWTKKDGKITVNSGIGDEDPLAHKIENLGMPYN
                     GSYTLVSSNGSEEYLELNIIIDGEISKSGLDKLEEDYGSSIKIPNDKNMIITFLSNKS
                     DN"
     gene            4182..4556
                     /locus_tag="ACGI5H_003829"
     CDS             4182..4556
                     /locus_tag="ACGI5H_003829"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861518.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0045892 - negative regulation of
                     DNA-templated transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="BlaI/MecI/CopY family transcriptional regulator"
                     /protein_id="HFG9699501.1"
                     /translation="MKEEILIEKLLRAELIVMEYLWKKDTLMPKKEIVKEIKQIYGWH
                     KSTIKILLKRLVAKRYLARYIINSQSHYKIIDSKEYYTFKKKVLKSSKSIKIMRSLTT
                     THKNVSKEKLDLLDEYYRNLKE"
     gene            4661..5015
                     /locus_tag="ACGI5H_003830"
                     /pseudo
     CDS             4661..5015
                     /locus_tag="ACGI5H_003830"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430377.1"
                     /note="frameshifted; internal stop; incomplete; missing
                     C-terminus; Derived by automated computational analysis
                     using gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0045892 - negative regulation of
                     DNA-templated transcription [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="BlaI/MecI/CopY family transcriptional regulator"
BASE COUNT         2025 a          617 c          575 g         1798 t
ORIGIN      
        1 aaagagtctt tccgaaaaat ctatatatta taatatagtt atattttctg cttgaggacc
       61 tctagcgcct ttaactatat caaagcttac tttttgacct tcttctaatg atttaaatcc
      121 tgaagtttgt atagctgaga aatgagcaaa tacgtcatct ccactttcca ttgatataaa
      181 tccaaatcct ttttcattat taaaccattt tactattcca ttattcatta aaaatactcc
      241 tattaaccta tatcaagata tacttgattt acttgtgtat taccacaaat attattgtat
      301 catagattaa cataaatgtc tatttaatta taatttttag ttaacatttt tatttattct
      361 taatatgaaa ataaatttaa acattttata ttaccaatat attaatgtaa atgtagataa
      421 aactaaaaag ggttttctag aaaaaaatct gtctaattat acttacttac caataccatc
      481 acttgatgca agcaagattc cacaactttt tctccgtact ctaatataaa atcatctaac
      541 tgtgtatcta taaaatcaca ataatcgtat gaattactaa tataagcagt taacatatgt
      601 gtacatttat ccattttatc tctaaacata atgtatttat ccccctaaaa aactttcatg
      661 aaaaacaaaa agaaaatatc tttttggcaa ctggctgaca taacttattt tataagcgtt
      721 agtccctata gctttgcgtc actaaatttc tctagttttg ccgatttagt tttattctac
      781 agattaataa tacaatagaa ttagttatca ttcaacatat ctagttgaat aattaataaa
      841 tttatatatg aactttaaat tatttgaaaa aataaaaagc ccctctgtca ggagtgactt
      901 aaaaattgaa tttaagtttg tatttaaaac acatttttaa taatgcaaaa actaatcaaa
      961 aataaacaat tcatcaatag gtgtatctac tatttttgat atatctattg ctaatttcaa
     1021 agaaggatta tactttcctg cttctaaacg cataatggtt tctcttctaa ctcctacttt
     1081 ttctgctaat tgttcttgag ttaattcttt taattgtcta tattttttta ggttacaagt
     1141 gaatttaggc atattatttt tcctctaaaa tataaagttt tatagcataa acatttaaag
     1201 tgattgcata tgtaattgat agtaaaacac acattaattc tatattccta gacactatag
     1261 taatacacca taaaatgaat aattctataa tagcaagctg tcctgtaaat gccatagctg
     1321 ctttttcatc ttgtacatac ctttcatctg ctttatcacc atttattttt gctataataa
     1381 agtttgagaa aaaagcaaaa aatccaatat atgtaaggtc agcaacattg ccagatgaaa
     1441 aatatctaag acttaaaaat ccaaggaaac cacaaaaacc cataaaaaat tttttctgaa
     1501 tcatttttta tcctccttag taattttaaa agagatatat ttatatcttt atgatacaaa
     1561 tatatctctt ttatattctt ttgtcaatag aaaatcagta ttatacaata tttatactgc
     1621 accataattg ttagagcaaa aatctaatgc ttgagatgtt tatgtatgac taaatatgat
     1681 tttaatttca aattaaaagt agctaaattt tatttgaata gagaaggaag agatatttta
     1741 atagtaaaac aatatggagt ttatgaccat tctcaagttg aaagatgggt taatatatta
     1801 ggagagagtg aactaaaaat aaaaaaattt tctatactat atggttcaag ttagatgtta
     1861 taaactatat gatgataact aaatatagtg tacaataaat cgctaagtat tttggaataa
     1921 acaatagcac agttatagca acatgaaaat aaaaattttt acatagtggt gttgatgcct
     1981 tttctaaaat gaaaggaaga ccataatgaa taaaaacaaa aacactaaag aaaaaataaa
     2041 ttaacaagag aacaagaatt agaatatgaa aataaatttt taaaagatga gcttgagttt
     2101 ttaaaaaaga tgtgtgtctc agggaagcca cattaaaaaa cagtggtatc attattaatc
     2161 aaaagaaagt tagatgtatt atcaaaaaat tagaacttaa atgcatagca ttttttcata
     2221 aatcacataa atataactcc tataaaggta taattggaaa agtaaaaaat aataaaacaa
     2281 atagaagatt taaaacatca atagcatatc agaaaataac aaatgatatg ctagaattta
     2341 taaaatatat ctaatgataa aaatggaaaa tcaattataa aaaaggcata tctcgattca
     2401 ttttttgtta tatagtcaaa taagaatact atagatgaaa gatacgattt tgcatatgta
     2461 ttaagtaagt attctgatgt ttttggttga tacacatgca ataaagaagt tgtgtttgca
     2521 gataaattag caaaactata gtataagttg caacaataaa gaaaatgaaa attatcatac
     2581 taaagcataa ggcatgttac aattttatta gataggacat taacatacac taaagtactt
     2641 tttattataa agagtactta tttttttgaa attcattaat gtataaacta tcaagaatat
     2701 tactcaacat aatttaaaaa caacttgaat aggtattttt aaattatgtg atataataaa
     2761 aaatagaagt gtatgccaat acacttctgt agttataact aagcattcta ttcttgagga
     2821 gtgctttttt catttttata accaactctt tttactttaa caataattat cagacctata
     2881 tatttatttt taattgtctg atttattaga taaaaaagtt attatcatat ttttatcatt
     2941 tggtattttt attgaactac cataatcttc ttctaattta tctagaccac ttttacttat
     3001 ttctccatct ataattatgt ttaattctaa gtattcttca ctaccattag atgacactaa
     3061 agtgtacgaa ccattataag gcatgcctaa attttctatt ttatgtgcca aagggtcttc
     3121 atcaccaata ccagagttta ctgttatttt tccatctttt ttagtccacc atattatgtt
     3181 tccttcagta tattttgatt catctgcata gtagctaaga gacgcacttt ttattgcact
     3241 tatatcagct tcaagtttag ctatctttgc tttttctata tttttaaata atgctggaag
     3301 tgctactatt gccaatattc ctattatagc aattactact aataattcca ctagagtaaa
     3361 tcctttttta tttttcattt atttcccctc catataaaat taataatata taaattttta
     3421 ttttgttaat ttctactttc tatattttac catatataga caaaaaaatc actttctatg
     3481 acaaatatac tattatttta caatttatgg aaatgattta aaatgacatt tcttgttaga
     3541 aaagatataa gaaatggatt aaaataaaga aaactacagt catatcaatg tcaataatat
     3601 tatttaaaag cagatgaaaa taaaaagagg actcagaaaa taatgtctat ttaattatac
     3661 ttacttacca ataccataac ttgatataaa caagattata ctacattttt ttatgctcta
     3721 gtataaaatc atctaactgt gtatctataa aatcaaaata attatatgaa ctatcagtat
     3781 aataagtcaa aatatgtata catgaataca tattttaaaa gatatatatt attacatacc
     3841 taaaaaactt tcataaaaac aaaaataaaa tatgctttta gtaacttgtt aacataactt
     3901 ataatttatt ttataagcat tagcctatat agctttgtgc tactaaatct ctttgattct
     3961 aacgatttag tgctattcta caactaaaat aatacaatag agctatttat tgtttggtag
     4021 cattgtttgt aaattaaaca aatttataca tatgaatatt attttacatt caaaaaaaca
     4081 gactaaatat gtagaatatt tggtaaaact tacctctagt ttttgtctta aaaagctcct
     4141 attattaact taagttagaa gaattaagga agtgacataa attgaaagaa gaaatattaa
     4201 tagaaaaatt attaagagca gaattaatag taatggagta tttatggaaa aaagacactc
     4261 taatgcctaa aaaagaaatt gtaaaagaaa taaaacagat ttatggatgg cataaaagta
     4321 caataaaaat actactaaaa aggctagttg ctaaaaggta tttggctaga tatattataa
     4381 attctcaatc tcattataaa ataatagata gtaaagaata ttatactttt aagaaaaagg
     4441 tactaaaatc tagtaaaagc ataaaaataa tgcgttcact taccactaca cataaaaatg
     4501 taagtaaaga gaagttagac ctattagatg agtattatag aaacttaaaa gaatgatata
     4561 gtaaaaatcg aatgtaatta tttaccttaa ttcttttgtt tgtaaaactt tattgataca
     4621 gaatttaaca tatacataaa ttggtaaagg aatgtatact atgaaaatta gtaaattacc
     4681 agaagcggaa ttaaaagtta tgagatatat ttgggaatca gaaaaggtat taatatcaag
     4741 agaaatcacc aagtctatgg aacaaaaata tgaatggaaa gatacaacta tatttacagt
     4801 attaaaaaga ttactaaaga agagagtttt tagaagcgga gaaaatagat aagtgtacac
     4861 actataatgt attagtaaaa aaaaataata tcagagattt taaacaaaag aatttttaaa
     4921 gaatacacat aaaaattcaa tattaagttt aatgtcagca ctatgtagta aggatgatga
     4981 agtagatggt gatattttaa atttattaga agaat
//
LOCUS       DAYAOO010000165         5005 bp    DNA     linear   BCT 12-OCT-2024
DEFINITION  TPA_asm: Clostridioides difficile isolate ST8-SSI-h139-18
            SAMN40601845-rid21577343.denovo.169, whole genome shotgun sequence.
ACCESSION   DAYAOO010000165 DAYAOO010000000
VERSION     DAYAOO010000165.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN40601845
            Sequence Read Archive: SRR28438827
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 5005)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5005)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-MAY-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-MAY-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002157583.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002157583.1
            Genome Coverage       :: 163x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/11/2024 16:19:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 4,038
            CDSs (total)                      :: 3,963
            Genes (coding)                    :: 3,930
            CDSs (with protein)               :: 3,930
            Genes (RNA)                       :: 75
            rRNAs                             :: 6, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 60
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 33
            CDSs (without protein)            :: 33
            Pseudo Genes (ambiguous residues) :: 0 of 33
            Pseudo Genes (frameshifted)       :: 7 of 33
            Pseudo Genes (incomplete)         :: 25 of 33
            Pseudo Genes (internal stop)      :: 11 of 33
            Pseudo Genes (multiple problems)  :: 8 of 33
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5005
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN40601845-rid21577343.denovo.169"
                     /isolate="ST8-SSI-h139-18"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Denmark"
                     /collection_date="2018"
                     /collected_by="Statens Serum Institute"
     gene            642..4784
                     /locus_tag="ACGI5H_003831"
     CDS             642..4784
                     /locus_tag="ACGI5H_003831"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014466370.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SdrD B-like domain-containing protein"
                     /protein_id="HFG9699502.1"
                     /translation="MATVSGQIVFDRNRSATIDSGDSGIANIPVVLQDIATGVRLVVL
                     TDASGNYVFTNVPNGNYRIVEAFGTTGGVPTPGNFATAIVGPVPIAEMPPISSVTSPP
                     IGSTNLDGTTPNTLLITVAGSDITNQNILNGPVIYTPIENILDSCVSVSNINLITDAD
                     NGTFGFFPPGTPSNTGPEIEPYPNVTPDFTYVVPDPTKFTPLDGEYTVQNIMTNAMSN
                     VIGAWWRIADHTTGNETGRMMVVNGFNPGAVFFKSTVQVTPNTNYLFSTWILNLFKVT
                     GYPPPQLGVRIFDQNNNILYQATLGAQIPVNTNAPEWKEVGTVINSQNNNQLTVEFFS
                     EGESAIGNDYAIDDVSLREIAVPTFTPIKTSNTETANVGDIITYTVTLDNTCDSPLTN
                     VFFRDLIPNGLEFIPGTVTVDGVSVPGVDPNTGFPLPDIGGGTGVEVTFDVVVESIPN
                     PNPTNNIATIDYSYTPVEGGIPNDFSVDSNPVPVEVISADIEVTKLSEPTIVNPGEEL
                     IYTIKVVNNGPFPSENVVLTDDVPASIVNPEYSLDGGVTFQPWTGSLNIGTLEVGETR
                     VIIIRGIVNPSTVGIITNTAVVSSTTADPNLNNNTSTIETEVNLLADILVMKTAEPNS
                     AVPGTLLRYTIQVENLGPANAENVILNDDIPASIINPEYSLDGGASFQPWNGSLNIGT
                     LNSGISLTVLIQGTVSLNSSEYIVNTATVSSTTPDPDLSNNISTIITPVNPQAGISII
                     KVADEDVAVPGEEFVYTIEIFNEGPSNATNVVLTDDIPDVILNPEYSLDGGATFQPWT
                     GSLNIGTVAPGQLIRIIIKGLVSSTATGDITNTAEVSADVPEPVTDSSTVTTPIVPSA
                     DIEVIKTSNMDTAVPGETFSYTITVTNLGPSAAQSIVLTDDIPDVILNPEYSLDGGVT
                     FQPWNGNLSIGTLDAGEIRSIIIRGTVSQTAVGTIINTATISSTTPDPNPDNNTSTDE
                     TDISPLADISVIKGNEPVAIPGGRFIYGIEIANAGPSFAENVTLTDNIPASILNPEYS
                     IDNGVTFQPWNGSLNIGTLDAGEIRNIIIRGTVSQTAIGTIINTATVSSTTPDPNLNN
                     NISTSEAEVSSSADISVVKRSNQTVVVPGDVLDYTIEVRNAGPSTAQNVTLTDNIPAS
                     ILSPEYSIDNGVTFQPWNGSLSIGTLDAGEIRNIIIRGIVSQTAIGTIINTATVSSTT
                     PDPNPDNNTSTSEIDISSSADISVIKLANKTEACVGEQIDFVIVVSNAGPENAQNVTL
                     IDNVSDKLKKAVFSLDRGVSFQPWTGSLNIGTLPAGTLRVIILRGIIKSTCLDRLTNI
                     AEITSTTPDSNLNNNISRVQVEIKQCCCNDCCCNNCSNCCCNDCGCKDCCCNCCKNDF
                     WC"
BASE COUNT         1936 a          727 c          835 g         1507 t
ORIGIN      
        1 taaaaataaa gtcaactaaa attattgatt ttagattaaa gtaccggatt aagcatttaa
       61 gtagatttta agcttgattt gattagaaag gtacaaacta tcaccgaaaa aaattaaacc
      121 catttaaaaa gcaatataaa agcttgttat ttttgagaaa aatagaccct ctaaactcaa
      181 ttagattaaa aataaaatac agaaaattat atctctaaat atcttaaata attaagttta
      241 aattttacga tattttgttt gatgatttat aatataaaag catactctta atcttcaaaa
      301 tttaaaaaga gtaaaaaata acaaaaaaat cactgacatt tcactgacaa attgtaattt
      361 tgttattata aatacattga aaatacttga ttattgaaaa atggcataaa ataatacatt
      421 ttatgccatt tgctattatt tgatagtttt taacttatga cataagatat tttttaacat
      481 atacaataaa atataaaaaa attgatattg caaataaaaa aaaatacata ttagatgtta
      541 tagaaaaaaa gcgcacttat aggcttaaaa tgtcacataa aagagtttta aagaataata
      601 tattatgaac acaaattttg taatcacaaa ggagtgataa tatggcaaca gtatcaggac
      661 aaatagtttt tgatagaaat agaagtgcta ccattgattc tggagactca ggaatagcca
      721 atataccagt tgtattacaa gatatagcaa ctggagttag acttgtggtt ctcacagatg
      781 catcaggaaa ttatgttttt actaatgttc caaatggtaa ctatagaatt gtagaagctt
      841 ttggaactac aggaggagta ccaacaccag gaaattttgc aacagcgata gtaggtccag
      901 ttccaattgc agaaatgcca cctattagtt ctgtgacaag tcctcctatt ggttcaacaa
      961 acttagatgg tacaacacct aacacactat taataacagt agcaggttca gatataacaa
     1021 atcaaaatat attaaatggg cctgtgattt atacacctat agagaatata ttggattctt
     1081 gcgtatctgt atctaatata aaccttatta cagatgcaga taacggaaca ttcggttttt
     1141 ttccaccagg tacaccaagt aatacaggac ctgaaataga accttaccca aatgtgacgc
     1201 cagattttac gtatgttgta ccagacccaa ctaagtttac acctttagat ggagaatata
     1261 cagtacaaaa tattatgaca aatgcaatga gtaatgttat aggagcttgg tggcgtattg
     1321 ctgaccatac tacaggaaat gaaacaggaa gaatgatggt ggtaaatggt tttaatcctg
     1381 gagctgtatt ttttaaatca acagtacaag ttacacctaa cactaattat ttatttagca
     1441 cttggatttt aaaccttttt aaggtaacag gatatccacc accacagcta ggtgtaagaa
     1501 tatttgacca aaataataat atactatatc aagcaacatt aggagctcaa attccagtta
     1561 atacaaacgc accagaatgg aaagaagtag gtactgtgat taattctcaa aataataatc
     1621 aacttacagt agaatttttt agtgaaggag aaagcgccat tggaaatgac tatgctatag
     1681 atgatgtttc tttaagagaa atagctgttc caacttttac tccaataaaa acaagtaaca
     1741 cagaaactgc taatgtaggt gatataatca catatacagt tacattagat aatacttgtg
     1801 atagcccttt aactaatgta ttttttaggg atttaattcc aaatggttta gagtttatac
     1861 ctggaactgt aacggttgat ggagtatctg taccaggagt agaccccaat acaggtttcc
     1921 cacttccaga tattggagga ggaacagggg ttgaagtaac ttttgatgtt gtggttgaaa
     1981 gtattcctaa cccaaatcct actaataata tagctactat agattactcc tatacacctg
     2041 tagaaggcgg tataccaaat gatttttcag tagattctaa tccagttcct gttgaagtaa
     2101 tctcagcaga tattgaagtt acaaaattat ctgaacctac tatagtgaat ccaggagagg
     2161 aattaatata cactataaaa gtagtaaata atggaccatt cccatctgaa aatgtggttt
     2221 taacagatga tgtaccagct tctattgtaa atccagagta ttcattagat ggaggagtaa
     2281 cttttcaacc atggactgga agtttaaata tagggacatt agaagtagga gagacaagag
     2341 ttattataat taggggtatt gtaaatccat caacagtagg aattataaca aatacagctg
     2401 tagtatcttc aactacagca gacccaaacc ttaataataa tacatctaca atagagacag
     2461 aagtgaattt attagcagat attttagtaa tgaaaacagc agaacctaat tcagctgttc
     2521 caggtacttt attgagatat actattcaag tagaaaactt aggaccagca aatgctgaaa
     2581 atgtaatatt aaatgatgat attccagctt ctattataaa tccagaatat tcattggatg
     2641 gaggagcaag ttttcaacca tggaatggaa gtcttaatat aggaacttta aactctggaa
     2701 tttcattaac agttttaatt caaggaacag ttagtttaaa ttcttcagaa tatatagtaa
     2761 atacagcaac agtttcttca actacacctg acccagattt aagcaacaat atatctacca
     2821 ttattacacc agttaaccca caagcaggta tttctattat aaaagtagct gacgaggatg
     2881 tagctgttcc aggagaagaa tttgtatata caattgaaat ttttaatgaa ggaccatcta
     2941 atgctacgaa tgtagtttta acagatgata taccagatgt tattttaaat ccagaatatt
     3001 cattggatgg aggagcaact ttccaaccat ggactggaag tcttaatata ggtacagttg
     3061 caccagggca attaataaga attatcataa agggattagt aagttcaact gctacaggag
     3121 atattactaa tacagcagaa gtaagtgcag atgtaccaga accagttacg gattcatcaa
     3181 cagtgacaac tcctatagtt ccatcagcag atatagaagt aataaaaact agcaatatgg
     3241 atacagcagt tccaggagaa actttcagtt atactataac agttacaaat ttaggaccat
     3301 ctgctgcaca aagtatcgtt ttgacagatg atataccaga tgttatttta aatccagagt
     3361 attcattgga tggaggagta actttccaac catggaatgg aaatcttagt ataggcactt
     3421 tggatgctgg agaaataaga agtattataa taagaggaac agtgagccag acagcagtag
     3481 gtacaattat aaatacagca acaataagtt caactacacc tgacccaaat ccagataata
     3541 atacttcaac agatgaaaca gatataagtc cattagcaga tatttctgtg ataaaaggca
     3601 acgaaccagt tgctatacca gggggaagat ttatttatgg aattgaaatt gcaaatgcag
     3661 gaccatcttt tgcagagaac gtaactttaa cagataatat accagcttct attttaaatc
     3721 cagagtactc aatagataat ggagtgactt tccaaccatg gaatggaagc cttaatatag
     3781 gtactttaga tgctggagag ataagaaata tcataataag gggaacagta agtcaaacag
     3841 caataggcac aattataaat acagcaacag taagttcaac tacacctgac ccaaatctaa
     3901 ataacaatat ttcaacatca gaagcagagg taagttcatc agcagatatt tctgtagtaa
     3961 aacgaagcaa tcagactgtt gttgtaccag gagatgtact agactataca attgaggtga
     4021 gaaatgcagg accgtctact gctcagaacg taactttaac agataatata ccagcttcta
     4081 ttttaagtcc agaatattca atagataatg gagtgacttt tcaaccatgg aatggaagtc
     4141 ttagtatagg cactttagat gctggagaga taagaaatat tataataagg ggaatagtaa
     4201 gtcaaacagc aataggtaca attataaata cagcaacagt aagttcaact acacctgacc
     4261 caaatccaga taataatact tcaacatcag aaatagatat aagttcatca gcagatattt
     4321 ctgtaataaa attagcaaat aaaacagaag catgtgtagg agagcaaata gattttgtaa
     4381 tagtagtatc aaatgcagga ccagaaaatg ctcaaaatgt tactttaata gacaatgttt
     4441 cagataagct taagaaagca gtattttcac ttgatagagg tgtaagtttc caaccatgga
     4501 ctggaagtct taatataggt acactaccag ctggaacttt aagagtgatt atattaagag
     4561 gaattataaa atcaacatgt cttgatagat taacaaatat tgcagaaatt acttcaacaa
     4621 caccagattc aaaccttaac aataatatat caagagtgca agtagaaata aaacaatgtt
     4681 gttgtaatga ttgctgttgt aacaactgta gtaattgttg ttgcaatgat tgtggttgta
     4741 aagattgttg ctgtaattgt tgtaaaaatg acttttggtg ttgattttat aaaataattt
     4801 tgtatacctt aaattaaact gaaataaaaa ataaattcac atatgagtaa aatattttat
     4861 aaatattaat aaattttcta tctttgatat ggaccacatt cgtaatacta gttattaaat
     4921 gaagtggtcc tttttaattc attaaaatta tttattctaa ttaaatttta aatgtattaa
     4981 ataattttaa ttttttataa aaaat
//
LOCUS       DAYAOO010000166         4508 bp    DNA     linear   BCT 12-OCT-2024
DEFINITION  TPA_asm: Clostridioides difficile isolate ST8-SSI-h139-18
            SAMN40601845-rid21577343.denovo.170, whole genome shotgun sequence.
ACCESSION   DAYAOO010000166 DAYAOO010000000
VERSION     DAYAOO010000166.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN40601845
            Sequence Read Archive: SRR28438827
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 4508)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4508)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-MAY-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-MAY-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002157583.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002157583.1
            Genome Coverage       :: 163x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/11/2024 16:19:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 4,038
            CDSs (total)                      :: 3,963
            Genes (coding)                    :: 3,930
            CDSs (with protein)               :: 3,930
            Genes (RNA)                       :: 75
            rRNAs                             :: 6, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 60
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 33
            CDSs (without protein)            :: 33
            Pseudo Genes (ambiguous residues) :: 0 of 33
            Pseudo Genes (frameshifted)       :: 7 of 33
            Pseudo Genes (incomplete)         :: 25 of 33
            Pseudo Genes (internal stop)      :: 11 of 33
            Pseudo Genes (multiple problems)  :: 8 of 33
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4508
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN40601845-rid21577343.denovo.170"
                     /isolate="ST8-SSI-h139-18"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Denmark"
                     /collection_date="2018"
                     /collected_by="Statens Serum Institute"
     misc_binding    88..322
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            372..1391
                     /gene="pheS"
                     /locus_tag="ACGI5H_003832"
     CDS             372..1391
                     /gene="pheS"
                     /locus_tag="ACGI5H_003832"
                     /EC_number="6.1.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436795.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0004826 - phenylalanine-tRNA ligase
                     activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006432 - phenylalanyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phenylalanine--tRNA ligase subunit alpha"
                     /protein_id="HFG9699503.1"
                     /translation="MQEKLLALREAALAEIKEAQSIESVESLRVKYLGKKGEITAILK
                     EMGKLSAEERPVVGKVANEVRENIELSINSKKEEINAIEKERKLKEEVIDVTQPGKVL
                     KVGKKHPITQIIDEVTDIFIGMGFSIAEGPEVETVENNFDALNAPKDHPSRDMSDTFY
                     INDGVLLRTQTSPVQVRTMRSQELPIKVIAPGRCFRSDSPDATHSPMFHQIEGLVVGK
                     DVTMAEFKGTMDIFVEKLFGSDIKTKFRPHNFPFTEPSAEVDVTCFKCGGKGCPMCKY
                     EGWIEILGSGMVHPNVLRNCGIDPEVYSGFAFGVGVERLAMLKYEIDDIRLLFENDMR
                     FLNQF"
     gene            1408..3801
                     /gene="pheT"
                     /locus_tag="ACGI5H_003833"
     CDS             1408..3801
                     /gene="pheT"
                     /locus_tag="ACGI5H_003833"
                     /EC_number="6.1.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888509.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000287 - magnesium ion binding [Evidence
                     IEA];
                     GO_function: GO:0004826 - phenylalanine-tRNA ligase
                     activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006432 - phenylalanyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phenylalanine--tRNA ligase subunit beta"
                     /protein_id="HFG9699504.1"
                     /translation="MLVSLKWLRDYVDIDMDVKEFADKMTMTGTKVETIDYYGEEIEN
                     ILVGKILEIKQHPNADKLVVTKVDIGDKVVQIVTGATNISEGDYIPVAVNGSKLPGGV
                     EIKQTDFRGELSDGMMCSAAELGIDEHYIEEYKRGGIYILDHEDSYELGKDIKDVLGL
                     KDALIDFELTSNRPDCKCMMGIAREAAATIGTKVKYPEIEVKESDEEIDFKVEIDNPD
                     LCRRYVARMVTDVKIEPSPYWMQRRLTEAGVRPISNIVDITNFVMLELGQPLHAFDIN
                     QVETGRIVVRNAKDGEKLVTLDDVERTLDKDMLVITNGEKSLGLAGVMGGANSEITSN
                     TKTVLFESANFKPENIRMTAKKVGIRSEASSRNEKDLDPNLAEIAANRAAQLVEMLGA
                     GKVLKGVVDVYPNKPEPKKLVVNPQRINHLLGVDVPMEQFVGILESLEFKCNLVANDK
                     LEIDVPSFRTDMEQEADVWEEIARIYGFENIPSVQLEGNTTAGIKTSKQKFMDALKDN
                     STAVGLNEILTYSFVSPKGVDKIRVPEGNAKRNFVKLLNPLGEETSVMRTTLIPNMLD
                     VLSTNVSHKIEEVSAFECGHIFIPQDSELPKEENRMCVGMYGKDVDFFALKGTIETIL
                     VNVGFKGYEIEPQDNNTTFHPGRCAKIVYNNKYVGTLGELHPDVIENYNLGQRVYVAE
                     IDIDFVFDNSDRTKNYVPLPKYPSTSRDIALIVKDDVFVKQIEDIIKENGQGLVESYK
                     LFDVYKGSQIEAGYKSIAYSITYRSKDKTLTDEDVAKVHDKILSELSEKLNANLRSN"
     gene            3826..4416
                     /gene="zapA"
                     /locus_tag="ACGI5H_003834"
     CDS             3826..4416
                     /gene="zapA"
                     /locus_tag="ACGI5H_003834"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905089.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0051301 - cell division [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein ZapA"
                     /protein_id="HFG9699505.1"
                     /translation="MNKVMVKIHGAEYPMVGDKSEKFMISIADFVDKEMDKITRQNPK
                     LSLSVAAILTALNISDLLFECSDENEKLIKANEELSKKVGASNEELQLEIKSLKLTIA
                     EKEAENREAETKMKELIEIIENKKQEIFELSNTTEGSRAELDAYKNKIEELSTQLEEA
                     NERATIAENLASEFQNKAYDLQLKCTGLNNDAKNVE"
BASE COUNT         1781 a          521 c          922 g         1284 t
ORIGIN      
        1 aaattaatta tgtattggat atatattaaa aatagtcaca taatttgaat ggaaatgata
       61 taatactaaa ataaacaata taatattgta aatgcaatga aagaggaaag tattttgatt
      121 aaacttagta aagagataaa cacctaggct gggagtgttt tctaagaggt catgagaagt
      181 tccctctgga gtaacagagc tgaaatttta cagtaggctt tgacgtcaaa aacgcgttaa
      241 gtttgttaga ggtggtttga tgatttttaa attgttaaac tactagggtg gtaccgcgaa
      301 actatagcct ttcgtcccta gacagggatt gaggggcttt ttttatacaa aaaaacgaaa
      361 gggtgatatg tgtgcaagaa aaattacttg ctttacgtga agcagctttg gctgaaataa
      421 aagaagcaca aagcatagaa agtgtagaaa gtttaagagt taagtactta ggaaaaaaag
      481 gtgagataac tgccatactt aaagaaatgg gtaaattatc tgctgaagaa agaccagtag
      541 ttggtaaggt tgccaatgag gtaagagaaa acattgaact tagcataaat tctaaaaaag
      601 aagaaataaa tgctattgaa aaagaaagaa aattaaaaga ggaagtgata gatgttactc
      661 aaccaggaaa agttttaaag gttgggaaga agcatccaat aactcaaatt atagatgaag
      721 taacagatat atttatcgga atgggattct ctatagcaga agggccagaa gttgagactg
      781 ttgaaaacaa ctttgacgca ttaaacgctc ctaaagacca tccatcaaga gatatgagcg
      841 atacattcta tatcaatgat ggggtattac ttagaactca aacatctcca gttcaagtaa
      901 gaactatgag aagtcaagag ttaccaataa aagtaattgc accaggtaga tgttttaggt
      961 cagactcgcc agatgctaca cactcaccaa tgttccatca gatagaaggg cttgttgttg
     1021 gaaaagatgt tactatggca gaatttaaag gaactatgga tatcttcgtt gaaaaattgt
     1081 ttggttctga tatcaaaact aagtttagac ctcacaactt cccatttaca gaaccaagtg
     1141 cagaggttga tgttacttgt ttcaaatgtg gtggtaaagg ttgcccaatg tgtaaatatg
     1201 aaggttggat agaaatatta ggttcaggta tggttcatcc aaatgtgctt agaaattgtg
     1261 gaatagaccc agaagtttac agtggatttg catttggagt tggggttgaa agacttgcaa
     1321 tgcttaaata cgaaatagat gatattagat tattattcga aaatgatatg agattcttaa
     1381 atcaatttta attaggaggg tatgtagatg ttagtatctt taaaatggct tagagactat
     1441 gttgatatag acatggatgt aaaagagttc gctgataaaa tgacaatgac aggaactaaa
     1501 gttgaaacaa tagattatta tggtgaagaa atagaaaata tattggttgg aaagatttta
     1561 gaaataaaac aacatccaaa tgctgataag ttggttgtaa ctaaagtaga tattggagat
     1621 aaagttgttc aaatagttac aggagctaca aatatatcag aaggagatta tattccagta
     1681 gctgtaaatg gttctaagtt acctggagga gttgaaatca aacagactga tttcagaggt
     1741 gaattatcag atggtatgat gtgttcagca gctgaactag gtatagatga acattacatt
     1801 gaggagtata aaagaggtgg tatatatatt ttagaccacg aagattctta tgaattagga
     1861 aaagatataa aagatgtttt aggattaaaa gatgctttaa tagattttga attaacttca
     1921 aacagacctg attgtaaatg catgatgggt atagctagag aagcagctgc aactatagga
     1981 acaaaagtaa aatatcctga aatcgaagta aaagaaagtg acgaagagat agatttcaaa
     2041 gttgagatag ataatccaga tttatgtaga agatatgttg ctagaatggt tacagatgta
     2101 aaaatagaac cttctccata ttggatgcaa agaagactta cagaagcagg agtaagacct
     2161 ataagtaaca tagtcgatat aacaaacttc gtaatgttag agcttggtca accacttcat
     2221 gcttttgata taaatcaagt agagactgga agaatagtag taagaaatgc taaagatgga
     2281 gagaaacttg taacattaga tgatgttgag agaacattag acaaagatat gctagttata
     2341 acaaatggag aaaaatcact tggtttagct ggtgtaatgg gtggtgctaa ctcagaaata
     2401 acttctaata cgaagactgt actttttgaa agtgccaatt tcaaaccaga aaacataaga
     2461 atgacagcta aaaaagttgg tattaggtca gaagcatctt caagaaatga aaaagactta
     2521 gaccctaatc ttgcagagat agcagcaaat agagctgcac aacttgttga aatgttagga
     2581 gcaggaaaag ttttaaaagg tgttgtagat gtatatccaa ataaaccaga acctaaaaaa
     2641 ttggtagtaa atcctcaaag aattaaccac ctattaggtg tagatgtacc aatggagcag
     2701 tttgtaggaa ttttagaatc attagagttt aaatgtaatt tggtagctaa tgataaatta
     2761 gaaatagatg taccaagctt tagaacagat atggaacaag aagctgatgt atgggaagaa
     2821 atagctagaa tttatggatt tgagaatata ccttctgtac aattagaagg aaatacgaca
     2881 gcaggaatta aaacttcaaa acaaaaattc atggatgctt taaaagataa ttcaactgct
     2941 gtaggattaa atgaaatatt aacatattca tttgtaagcc ctaagggagt agataagata
     3001 agagtaccag aaggtaatgc aaagagaaat tttgttaaat tacttaaccc attaggagaa
     3061 gaaacttctg taatgagaac tactttaata ccaaatatgt tagatgtttt atcaactaat
     3121 gtatctcata aaatagaaga agtatctgca tttgagtgtg gacatatatt catcccacaa
     3181 gattcagaat tacctaagga agaaaataga atgtgtgtag gtatgtatgg taaagatgtt
     3241 gacttctttg cactaaaagg aactatagaa actatacttg taaatgtcgg atttaaaggt
     3301 tatgaaattg aacctcaaga taataatact accttccacc ctggtagatg tgctaaaata
     3361 gtgtataata ataaatatgt aggtacatta ggtgaattgc atccagatgt tatagaaaac
     3421 tacaatctag gtcaaagagt ttatgtcgct gaaatagata ttgactttgt atttgataat
     3481 tctgatagaa caaagaatta tgtgccatta ccaaaatatc catctacatc aagagatata
     3541 gctcttattg ttaaagatga tgtatttgta aaacaaatag aagatataat aaaggaaaat
     3601 ggtcaaggat tagtagaaag ctacaagtta tttgatgttt acaaaggttc tcaaatagaa
     3661 gctggataca agtcaattgc atattcaata acttatagaa gtaaagataa aactctaaca
     3721 gatgaagatg tagctaaggt gcatgataag atattaagtg aattaagcga aaaattaaat
     3781 gctaacttaa gatcaaatta acaactaatg tcgggggagg ttaggatgaa caaagtaatg
     3841 gttaaaatcc atggcgctga atatccaatg gttggagaca aatcagagaa gtttatgatt
     3901 agtattgctg attttgtaga caaagaaatg gataaaataa cacgtcaaaa cccgaaattg
     3961 agcttatcag ttgctgcgat attaactgca ttaaatatat cagacctttt atttgaatgt
     4021 tcagatgaga atgagaagtt gattaaagcg aatgaagaat tgagtaagaa ggttggagca
     4081 tctaatgaag agcttcaatt agaaatcaaa tctttaaagc ttacgatagc agaaaaagaa
     4141 gcagaaaatc gtgaagctga aactaagatg aaagagttaa ttgagattat agaaaataaa
     4201 aagcaagaaa tattcgaact tagtaatacg acagaaggtt ctagagcaga gttagatgct
     4261 tataaaaaca agattgagga gttaagtact caacttgaag aagcaaatga aagagctact
     4321 atagctgaaa acttagcttc tgagtttcaa aacaaagctt atgatttaca gttaaaatgt
     4381 acagggttaa ataatgatgc aaaaaatgtg gaataaacta aaagatttgc tgtctcttgt
     4441 tttttgagac agcttctttt aatgtataaa tataaatgct atataaatat agataatgtt
     4501 taaatgta
//
LOCUS       DAYAOO010000167         4373 bp    DNA     linear   BCT 12-OCT-2024
DEFINITION  TPA_asm: Clostridioides difficile isolate ST8-SSI-h139-18
            SAMN40601845-rid21577343.denovo.171, whole genome shotgun sequence.
ACCESSION   DAYAOO010000167 DAYAOO010000000
VERSION     DAYAOO010000167.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN40601845
            Sequence Read Archive: SRR28438827
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 4373)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4373)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-MAY-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-MAY-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002157583.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002157583.1
            Genome Coverage       :: 163x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/11/2024 16:19:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 4,038
            CDSs (total)                      :: 3,963
            Genes (coding)                    :: 3,930
            CDSs (with protein)               :: 3,930
            Genes (RNA)                       :: 75
            rRNAs                             :: 6, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 60
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 33
            CDSs (without protein)            :: 33
            Pseudo Genes (ambiguous residues) :: 0 of 33
            Pseudo Genes (frameshifted)       :: 7 of 33
            Pseudo Genes (incomplete)         :: 25 of 33
            Pseudo Genes (internal stop)      :: 11 of 33
            Pseudo Genes (multiple problems)  :: 8 of 33
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4373
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN40601845-rid21577343.denovo.171"
                     /isolate="ST8-SSI-h139-18"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Denmark"
                     /collection_date="2018"
                     /collected_by="Statens Serum Institute"
     gene            658..1338
                     /locus_tag="ACGI5H_003835"
     CDS             658..1338
                     /locus_tag="ACGI5H_003835"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897205.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000156 - phosphorelay response regulator
                     activity [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HFG9699506.1"
                     /translation="MQIDVLIIDGDKNSSQELKNFLEGKGINVYLAYNCKDAIIKIFS
                     KKFDLIFLEIILVDGDGWDFCKKIRNITTCPIIHITYINENQSILNALNSGGDDYLIK
                     PLNLEILYAKVKAILRRRDLFLNNNKNNIKLEDYNRASGVIKLENKMIKLTPTENRLL
                     NYFIENAEKTLTIKEIYEHVWMNEYLDDNYSVVVAVSGLRKKIEKDYKNPQKIITIRE
                     VGYYFNKI"
     gene            1786..2070
                     /locus_tag="ACGI5H_003836"
     CDS             1786..2070
                     /locus_tag="ACGI5H_003836"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9699507.1"
                     /translation="MLVYNKSFYPNDIFPRLDFSKIKKQLKLIDNDLSDFGSICIIEK
                     EHYTISVNSIGEINVYYDLEYENKVYRIVYEIEKLFKSQVGRFSISTYRN"
     gene            complement(2841..3056)
                     /locus_tag="ACGI5H_003837"
     CDS             complement(2841..3056)
                     /locus_tag="ACGI5H_003837"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902968.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HFG9699508.1"
                     /translation="MAIVVNLDVMMAKRKISLKDLAEKIDITNANLSILKTGKAKAIR
                     FTTLNEICKALDCQPGDILEYVEDEND"
     gene            complement(3067..3534)
                     /locus_tag="ACGI5H_003838"
     CDS             complement(3067..3534)
                     /locus_tag="ACGI5H_003838"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424265.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2975 domain-containing protein"
                     /protein_id="HFG9699509.1"
                     /translation="MITKFFSNILSVFLYFLLSLLGVAGIIFLCMIPMFLYDFSSDKV
                     IALIARILYFSDYFIVILFLIFIINSTKYSPFVLENVKRFKVMGFCLLINTIIECING
                     YNLNTNNIRIFGTDSGGISPLMIISFIFALMCFVIAETFDKAIKIKEDNDLTI"
     gene            3878..3976
                     /locus_tag="ACGI5H_003839"
     CDS             3878..3976
                     /locus_tag="ACGI5H_003839"
                     /inference="COORDINATES: protein motif:HMM:NF022636.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9699510.1"
                     /translation="MFILKRLCKLVSINKSFSEEIPKNLKNTYMCI"
BASE COUNT         1841 a          364 c          555 g         1613 t
ORIGIN      
        1 caatagaggc attttaaaaa aaacataaat ttataatata aaattgtttt aagctccctt
       61 tccccaaaat aggaaatttt tattagcatt taataatgat ttttaatttt taatataata
      121 ttaaagaatt atttaagaat atttaatctc taaagcttaa attacaataa tattataaaa
      181 ataaaagtga tatattgtgt aataatcgaa attttatact ttggttaaaa taattttata
      241 tatagtgcct aatgtataac ctaatgctcg tagacaataa tgtggatatt atcaaattta
      301 tttttataat agaaatttta atttatatct atattaaatt gttaaagata taattatgag
      361 aataaaaaat atagctttga attatataat tgtatatgct tatctttata cagtaaataa
      421 aaaatcaaat gaaataccaa ataaagtgta tatcttaaaa taacttacta gagatacaag
      481 gatgctatgt gaattttgaa gtgtgcagtt tagataataa atatatataa ataataaaga
      541 aaatggattt atagtattta aaatttctta taagggtaaa aaatgctatt agaaaatgta
      601 ctaaaaatat ttttccaatt ctttatagaa aaataatgat atttaggaga gattgtaatg
      661 caaattgatg tattgataat tgatggagat aagaatagtt ctcaagagct gaaaaatttt
      721 ttagaaggaa aggggataaa tgtctattta gcatataatt gtaaagatgc tattataaaa
      781 atatttagca agaaatttga cttaatattt ttagagataa ttttagttga tggtgatggt
      841 tgggattttt gtaaaaaaat tagaaatata actacttgcc caattattca tataacttat
      901 ataaatgaaa atcaaagtat tttaaatgct ttaaattctg gaggagatga ttatttaata
      961 aagcctttaa atttagaaat attatatgcg aaagttaaag ctattttaag aagaagagat
     1021 ttatttttaa ataataataa aaataatata aaactagaag attataatag agctagtgga
     1081 gtaataaagt tagaaaataa aatgataaag ttaactccaa cagaaaatag attattaaat
     1141 tactttatag agaatgctga aaagactcta actattaagg agatatatga acatgtatgg
     1201 atgaatgagt atttagatga taattatagt gtagtggttg ctgtgagtgg attaagaaag
     1261 aaaatagaga aagattataa aaatcctcaa aaaattataa cgataagaga agtagggtat
     1321 tactttaaca agatataaag ctttataaac agaatgaatg ataaggcata gataatatgt
     1381 tagtatatta taagagtttt tgttctaacg atatatttgt aaaattagat ttaatttact
     1441 taattaaatt atagcagtag aataaatata aaaaatgtct gaaatattat agacatcagt
     1501 aaaatatata aaactataat ataagtcgta ataataaaac aaatgaatat taattaataa
     1561 aaagatagta gctattttta tatagctatt atttttttat tgttgtggat gaaaatatac
     1621 ttatatttta ctaatataca tttaaaaatt ataatttaaa gcattaaaaa ataaatttgt
     1681 attttgtttt atataaagta atttgaagaa tatggaaaaa cttgattagt acattattaa
     1741 ttagggtata aaatggtgta aatagaatga taaggggtgg atgaaatgct tgtatataat
     1801 aaaagttttt atcctaatga catatttcca agattagatt tttcaaaaat aaaaaaacag
     1861 ttaaaattga tagataatga cctgtcagat tttggaagca tatgtataat agaaaaagaa
     1921 cattatacaa taagtgtaaa cagtataggt gaaataaatg tgtattatga tttagagtac
     1981 gaaaataagg tgtatagaat agtttatgag attgaaaagt tatttaaatc tcaagttgga
     2041 aggtttagca tatctacata cagaaattga taattaaaaa agtagaaatt aaaaaactta
     2101 atactaaaga tatagataaa tatatgaggt aacagctaga gagagttgtt acccttttta
     2161 aatactaagt atatattatt cttattaatt ttttgtaaat tcactaaaag acctttttat
     2221 agaatattat tttctttttt tattaaatag gtaaatcagt aaaaatgcaa ttccagttcc
     2281 aattattatt ccaatgatat tttctataat taattttttt aatataaaag taaataataa
     2341 aaatgctata cataaaccta aaatatatcc tttaaaatag gttgaaagtt ttcttttcat
     2401 ataatcacca acttgtatca gatttagttt acttaattag agtataacag tgttgtaact
     2461 tcaaagagta tctaaaagat tacaaatgtt agataaaatc atcaataatg taatttataa
     2521 cacgtagcta taaactatgc aataatataa atggaggtat aagtaaatga aaaagttcca
     2581 tgttttgcta acagtttaaa taaatattag gtagaaaaga atgtatatag gaatctgtgg
     2641 taaaattatc aatttaaaag tattatttag tgtgatacag ttcttatagg taatggataa
     2701 caaatagata aaggaacagt ttctttctta gaacatattt tgttatgact ttaaacaaag
     2761 ttaatattaa tgtcaataat atagtaaaag aataaaaatc atatagtata ataaaaaaga
     2821 gtgtttctaa acactctttt ttaatcattt tcatcttcta catattcaag tatatcacct
     2881 ggctgacagt ctaaagcttt gcaaatttcg tttagagtgg taaatctaat agcttttgct
     2941 tttccagttt ttaaaattga taaatttgca tttgtaatat ctattttttc tgccaaatct
     3001 ttaagtgata ttttcctttt tgccatcatt acatctaggt taactactat tgccataaca
     3061 tcacctctat atcgttaaat cattatcttc ttttattttt atagctttat caaatgtttc
     3121 tgcaattaca aagcacatta gtgcaaatat aaaagagata atcataagtg gtgagatacc
     3181 gccactatca gttccaaaaa ttcttatatt attagtattt aaattataac cattgataca
     3241 ttcaattata gtgtttatca ataaacaaaa tcccattacc ttaaaccttt ttacattttc
     3301 aagtacgaat ggggaatact tagtactatt aattataaat atcaagaata agatgactat
     3361 aaagtagtca gaaaaatata gtattcttgc aattaaagcg attactttgt cagaactaaa
     3421 atcatataaa aacataggta tcatacataa gaatattata ccagcaactc ctaaaagtga
     3481 taatagaaaa tatagaaata ctgataatat attactaaaa aattttgtaa tcataaaata
     3541 tcatctcctt tatataaagt atattattga ttataatata caatttattg aatttcaata
     3601 ataaattatt gatataatat ataaaaccat tgtaatatac actaaaaata agaatgtata
     3661 aggtggtaaa tttatataaa aaagaatatg agttgtaaaa tattaaataa tattgtacta
     3721 attggaataa ttttaacttt attatagatt attttaatac cattagtact gatggtgtat
     3781 tttaaaattg gtataagcat tacaaatacg aatatgccaa ctgtaatatg taatataagt
     3841 agctatatac atatgtgctg tcccatatat tgtatcattg tttatattaa aaagattatg
     3901 taaattggta tcaatcaata aatcattttc agaagaaata cctaaaaact taaaaaatac
     3961 ctatatgtgt atttagttag atttgagatt tttacattta attttatagt gacaatatta
     4021 tattattttt atgatgtcta tttatatgca attactataa tatcagaact tatagtatca
     4081 tttgtttcat tatcaataag gttttttact ttagttttgt caattttatt aaaaaaagtt
     4141 attgatataa aagataagaa ggataaaact atatgacgga tttcaaacat aagagtggat
     4201 atttatataa tagatatttt atagttaatt ttattagatt ttatttaata ctgtaatatt
     4261 aatatcacaa tatattaata gtgtattaaa gattgaattt tgtagataac tataatttat
     4321 tgagagtgat aaataaaaat tatataatat tacagaagaa agagagggag aca
//
LOCUS       DAYAOO010000168         4358 bp    DNA     linear   BCT 12-OCT-2024
DEFINITION  TPA_asm: Clostridioides difficile isolate ST8-SSI-h139-18
            SAMN40601845-rid21577343.denovo.172, whole genome shotgun sequence.
ACCESSION   DAYAOO010000168 DAYAOO010000000
VERSION     DAYAOO010000168.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN40601845
            Sequence Read Archive: SRR28438827
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 4358)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4358)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-MAY-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-MAY-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002157583.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002157583.1
            Genome Coverage       :: 163x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/11/2024 16:19:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 4,038
            CDSs (total)                      :: 3,963
            Genes (coding)                    :: 3,930
            CDSs (with protein)               :: 3,930
            Genes (RNA)                       :: 75
            rRNAs                             :: 6, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 60
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 33
            CDSs (without protein)            :: 33
            Pseudo Genes (ambiguous residues) :: 0 of 33
            Pseudo Genes (frameshifted)       :: 7 of 33
            Pseudo Genes (incomplete)         :: 25 of 33
            Pseudo Genes (internal stop)      :: 11 of 33
            Pseudo Genes (multiple problems)  :: 8 of 33
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4358
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN40601845-rid21577343.denovo.172"
                     /isolate="ST8-SSI-h139-18"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Denmark"
                     /collection_date="2018"
                     /collected_by="Statens Serum Institute"
     regulatory      408..484
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF01734"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="Fluoride riboswitches increase expression of
                     downstream genes that help mitigate the toxic effects of
                     very high levels of fluoride; They are found in a wide
                     variety of bacteria and archaea; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="fluoride"
                     /db_xref="RFAM:RF01734"
     gene            749..2005
                     /locus_tag="ACGI5H_003840"
     CDS             749..2005
                     /locus_tag="ACGI5H_003840"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426825.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0005247 - voltage-gated chloride channel
                     activity [Evidence IEA];
                     GO_process: GO:0006821 - chloride transport [Evidence
                     IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="chloride channel protein"
                     /protein_id="HFG9699511.1"
                     /translation="MIEKFKTLIWIKMIIRIKSVYKTYGGLFFLGLIGIPVGAIIGLI
                     DTIFGTVLLKVTDIRETYPMYLIPFLAVVGVVIAYCYFKFGGKSSKGMNLIFEVGHGE
                     EEIIPLRLVPFIISGTWLTHLFGGSAGREGVAVQIGATFSHWVGKRLPIKNACSIFLV
                     TGMAAGFAGLFETPIAAILFAMEVLVAGSLEYQSLFPAFTASFTASSVSKALGLEKFS
                     FALSSKVVFDLSIFWKLIVLGIIFGMVGGAFAWCLKLSKRKIGNRLKNPMIRIAIIGV
                     CLSVLFLLFYKGRYSGLGTNLIQNSFYGGEIYSFDWLLKFILTILTLSAGFQGGEVTP
                     LFSIGASLGVLLAGFFNLPIELVAALGYASVFGSATNTFFAPVFIGAEVFGYSYLPYF
                     FVVCAISYIFNMDKSIYSLQKISTKQ"
     gene            2068..3261
                     /locus_tag="ACGI5H_003841"
     CDS             2068..3261
                     /locus_tag="ACGI5H_003841"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895690.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0015297 - antiporter activity [Evidence
                     IEA];
                     GO_process: GO:0006812 - monoatomic cation transport
                     [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA];
                     GO_process: GO:1902600 - proton transmembrane transport
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cation:proton antiporter"
                     /protein_id="HFG9699512.1"
                     /translation="MLTSLALIFLLGMASGGIFKRIKLPNLLGMLLTGIILGPYVLNL
                     IDNSILDISSDLRKIALIIILTRAGLSLDINDLKKVGRPAVLMCFIPATFEIIGMIVL
                     APKLLGVSILEAAVMGAVVGAVSPAIIVPKMLKLMEEGYGTEKSIPQMLLAGTSIDDI
                     FVIVMFTVFTGLAQGNSISAISFLQIPVSIILGVIVGAVIGICLAVFFKKVHMRDSAK
                     GVLLLSISFLMISLETALEGIVPFSGLLAVMSIGIFLQIKYRVVARRLSIKYSKLWVG
                     AEILLFVLVGATVDISYAFKAGIGAVILIFGVLLFRMVGVFFCLIKTNLTIKERLFCM
                     IGYIPKATVQAAIGGVPLAMGMASGQLILTLAVLAILITAPLGAFGIDVTYKKLLTSV
                     KGESK"
     gene            3462..3842
                     /locus_tag="ACGI5H_003842"
     CDS             3462..3842
                     /locus_tag="ACGI5H_003842"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426829.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0045892 - negative regulation of
                     DNA-templated transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="BlaI/MecI/CopY family transcriptional regulator"
                     /protein_id="HFG9699513.1"
                     /translation="MCLKKLSKLELVIMKFIWNLDIKTNSYEIIDYMKEEHNLPEKVA
                     LKTLSKLSKKRFLYVQETGKCMYYTVAIKEKAYLEFISRNVQNLLKNNFIRNLLVSFH
                     EEELTEEKIKSLENWVVNWEEAYV"
BASE COUNT         1565 a          434 c          776 g         1583 t
ORIGIN      
        1 taatataagc agagtgaaga aaaatattta aataatatat cataatgtag agtgagtaaa
       61 aatatttaaa tcatgtatca taatgcagag tgaagaaaat atttaaatca tgtatcataa
      121 tataagcaga gtgaagaaaa tatttaaatc atgtatcata atataagcag agtgaagaaa
      181 aatatttaaa taatatatca taatgtggag tgaggaaaaa tatttaagtt atgtatcata
      241 atgcaaagta aagaaaatca tttaaattat atatcataaa aataatatga aatattgaac
      301 actcataata ttagaggctt tactatttta attgataggt tatattattt ataacattaa
      361 aaatacaatt tacataaaat agacatatga aaaataaaaa attatataat aattatggga
      421 atgaggttct cccttggatg ataatatcct aaactgccaa tgagctgatg acttctatga
      481 tatcatagat gccaccagct ttttttgttg tttaaatcaa taaaatggag gtgaagtact
      541 tactaaattt ttatttttta aatttgaaga aatatttaat taatagaaaa aatagtagat
      601 tatatgttaa ttattttatt aagaatgggt taagagtgta cctatatcct atcaatttaa
      661 aaaacaatta tgatagtcat tacattgact acagttgatg taataaaact ttcaaaaaat
      721 cttatgatgc aaatagaaag gaattaaaat gatagaaaaa tttaaaactt taatatggat
      781 taaaatgata ataagaatta aaagcgttta taaaacatat ggtggactat tttttttagg
      841 actcataggt ataccagttg gtgcaattat aggtcttata gacaccatat ttggaacggt
      901 tcttctaaaa gttacagata ttcgagaaac atatccaatg tatctgatac catttttagc
      961 agtagtagga gttgttattg cttattgcta ttttaaattt ggaggaaaaa gtagtaaagg
     1021 aatgaatcta atatttgagg tagggcatgg agaagaagaa attattcctt taagattggt
     1081 tccatttata atatcaggta catggttaac ccatttattt ggtggtagtg caggacgaga
     1141 aggagttgct gttcagattg gtgcaacttt ttcacattgg gtaggtaaaa ggttgcctat
     1201 aaaaaatgct tgtagtattt ttctagtaac tggtatggca gctggttttg caggattatt
     1261 tgagacacca atagcagcaa tactatttgc tatggaggtt ttggtagctg gttcactgga
     1321 gtatcaatcg ctttttcctg cgtttactgc ttcttttaca gcaagttcag tatcaaaagc
     1381 tttagggtta gagaaatttt cttttgcact ttcttctaaa gttgtatttg acttgtcaat
     1441 attttggaag cttattgttt taggaattat ttttggaatg gttggtggag catttgcatg
     1501 gtgtctgaaa ttgtcaaaaa gaaaaatagg taatagatta aaaaatccta tgataagaat
     1561 tgctattatt ggagtatgtc ttagtgtatt attcctttta ttttataaag gaagatattc
     1621 aggtttaggg acaaatttaa ttcaaaatag tttctatggt ggagaaattt attcatttga
     1681 ttggctgtta aagtttatac ttacaatact gactttgtca gcaggttttc aaggaggaga
     1741 ggttacacct ttgttttcca ttggagctag tcttggtgta ttgttagcag gattttttaa
     1801 tttgccaatt gaattagttg cagcgcttgg ctatgctagt gtctttggta gtgctacaaa
     1861 tacttttttt gcacctgtat ttataggggc agaagttttt ggatacagct atttacctta
     1921 tttctttgta gtatgcgcta tttcatatat atttaatatg gataaatcta tttattcact
     1981 acaaaaaatt tcaacaaaac aataaataaa acaacataat gtatgattag aagagaaaga
     2041 atattagaga aaggataggg taggaatatg ttgacaagtt tagctttgat ttttttatta
     2101 ggaatggcct cgggaggtat ttttaagagg ataaagttac ctaacttatt gggaatgtta
     2161 cttacaggaa ttatattagg tccatatgtt ttaaatttga ttgataattc aatactagat
     2221 atttcttctg accttagaaa gattgcattg attattatat taacaagggc tggattatct
     2281 ttagatataa acgatttgaa gaaagtggga agacctgctg tacttatgtg ctttattcca
     2341 gctacttttg aaattatcgg aatgatagtt ttagcaccaa aattactagg cgtttctata
     2401 ttggaagcag cagtcatggg tgcagtagta ggagcagttt ctcccgcaat tattgtacct
     2461 aaaatgctta aattaatgga agaaggttat ggtacagaaa aaagtattcc acagatgctt
     2521 ttagcaggaa cttctataga cgatattttc gtaattgtga tgtttacagt attcacagga
     2581 ttggcacaag gaaatagtat atcagctatt agttttttac aaattccagt atcaattata
     2641 ttaggtgtaa tagttggagc agtgattgga atctgtttag cagtattttt taagaaggtt
     2701 catatgagag attctgctaa aggggtgttg cttttaagta tctcattttt aatgataagt
     2761 ttagagactg ctttagaggg tattgtgcca ttttctggat tattagcagt tatgagtatt
     2821 gggattttcc ttcagataaa atatcgtgta gttgcaagaa gattgtccat aaagtattca
     2881 aaactatggg ttggcgctga aattctcttg tttgttttgg taggggcaac agtagatata
     2941 agttatgcat ttaaagcagg aattggagct gtaattttaa tatttggagt tcttttattc
     3001 cgtatggtag gagtattctt ctgccttatt aagacaaatt tgacaataaa ggaaaggttg
     3061 ttctgtatga ttggctatat tccaaaggct acagtacagg cagcaatagg aggtgtacca
     3121 cttgcaatgg ggatggcatc tggacaactt attttgacgt tagcagttct agctatactt
     3181 ataactgcac ctcttggagc ttttggaatt gatgtaactt ataaaaaatt attaacttct
     3241 gtaaaaggcg agagtaagta aaaataaaga ttattttaac tggtaagtta tattttggaa
     3301 aaggattata ctattgaata caatataaaa aaatcatttg ggagattaag aaggtagaag
     3361 ttaagaacag attttaaggt atgttatgat tattagaatt gattttgtga aattattatt
     3421 gtaatattta attatataga taaagaagcg gagtgataac tatgtgttta aaaaaattat
     3481 caaaattaga gttagttatt atgaaattta tttggaattt agatataaaa accaattcat
     3541 atgagattat tgattatatg aaagaagaac ataatttacc agaaaaagta gctttaaaaa
     3601 ctttatcaaa actatcaaag aaaagattct tatatgttca agaaacaggc aagtgtatgt
     3661 attatacagt tgcaataaaa gaaaaggcat atttagagtt tatatcaaga aatgtgcaaa
     3721 atcttttgaa gaataatttt ataaggaatt tattagtatc atttcacgaa gaggagctaa
     3781 cagaggaaaa gataaagtcg ttagaaaact gggtagtaaa ttgggaagaa gcttatgtat
     3841 aaatgttatt atttttatta caatttagat aattttggtt ttgtaagctc tgcaactatt
     3901 tttagatggt tgcagagttt atttttattt tttattccct taagcaatac ttaaaagtaa
     3961 acgcatttat atttactaac ttcaattact tctaatactt aaattacttt ttaaaaatat
     4021 tttgatatgt catctctata gtaatctaga acttgtttct attctttata taaagttttt
     4081 atgaatgata tatataatat tcgttcattt gattaaaaat aacaaaatat taaataattc
     4141 tactctgata gtttgttaaa aaaataataa aaaatattaa taaacaaaaa aaaaattatc
     4201 ttaagagagg agaatgttct aaaatataaa aaggtttcta gatttcataa aagatactat
     4261 tttagtcttg aaaatattaa gtttgaaaag attttaattt aatgattgat taagttaaaa
     4321 atgtgtatgt aataaatttt attttattta ttgactaa
//
LOCUS       DAYAOO010000169         4170 bp    DNA     linear   BCT 12-OCT-2024
DEFINITION  TPA_asm: Clostridioides difficile isolate ST8-SSI-h139-18
            SAMN40601845-rid21577343.denovo.173, whole genome shotgun sequence.
ACCESSION   DAYAOO010000169 DAYAOO010000000
VERSION     DAYAOO010000169.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN40601845
            Sequence Read Archive: SRR28438827
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 4170)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4170)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-MAY-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-MAY-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002157583.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002157583.1
            Genome Coverage       :: 163x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/11/2024 16:19:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 4,038
            CDSs (total)                      :: 3,963
            Genes (coding)                    :: 3,930
            CDSs (with protein)               :: 3,930
            Genes (RNA)                       :: 75
            rRNAs                             :: 6, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 60
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 33
            CDSs (without protein)            :: 33
            Pseudo Genes (ambiguous residues) :: 0 of 33
            Pseudo Genes (frameshifted)       :: 7 of 33
            Pseudo Genes (incomplete)         :: 25 of 33
            Pseudo Genes (internal stop)      :: 11 of 33
            Pseudo Genes (multiple problems)  :: 8 of 33
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4170
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN40601845-rid21577343.denovo.173"
                     /isolate="ST8-SSI-h139-18"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Denmark"
                     /collection_date="2018"
                     /collected_by="Statens Serum Institute"
     gene            complement(211..1230)
                     /locus_tag="ACGI5H_003843"
     CDS             complement(211..1230)
                     /locus_tag="ACGI5H_003843"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422742.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="HFG9699514.1"
                     /translation="MMGKIRFGIVGTSNIANIFLRAASRVKDFELVAVYSRNLEKARE
                     FGTLYGASIFFDDLEQMAKSKDIDAVYIASPNALHSKQTITCLKHKKHVLCEKSLASN
                     LKEVKSMIKTAKDNNVLLMEAMRITCVPNFKAVKENLYKIGKIRRFFGSYCQYSSRYD
                     KYKNGIIENAFKKELSNGALMDIGVYCIHPMVNLFGAPKTVKAVSHILQTGVDGEGSA
                     VFQYDDMDAIIQYSKVADSYIPSEIQGEEGSIIIEKLNLFEKAIIKYRDGREEDISIP
                     KEKAEEKPREIEGMYYELVEFISLINNNKIESNINSHENSIIVMEIMDEIRRQSSIVY
                     PADSI"
     gene            complement(1406..1945)
                     /locus_tag="ACGI5H_003844"
     CDS             complement(1406..1945)
                     /locus_tag="ACGI5H_003844"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891160.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative ABC transporter permease"
                     /protein_id="HFG9699515.1"
                     /translation="MDNVGSLLYFLFNFFLYGFIGWIIENLYSYYKQGHFQEDGFLNG
                     PFKPMYAIAMSIIIEVSRFIDPNNIFALLLLCLVVPTVVEYITGILMKVYFNKVYWDY
                     SDYKYNSRGIVCLKFSVYWTILTFIGVRYFQVYIVDSLYSLIIPYWPIVVTILLVTLF
                     VDEILTIKFLRGNKDIVER"
     gene            complement(2046..2726)
                     /locus_tag="ACGI5H_003845"
     CDS             complement(2046..2726)
                     /locus_tag="ACGI5H_003845"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898027.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family hydrolase"
                     /protein_id="HFG9699516.1"
                     /translation="MQKVEGIIFDMDGVLFDSERISLEFWMETFEKYGYTMTKEIYTS
                     VMGRNRKGIIEGLTDIYDSSVPIIDLYDEKTKNMIEFMERKGAPIKLGVNELISFLKE
                     NGYKMAVATSTKRERAVKRLAKANLKDYFDAIVCGDDVVNSKPNPEIFLKAAKKINVN
                     PQNCIVIEDSPMGVEAAYNGGIRCINVPDLKEPDEQIKSQSHKILENLLEVREYLKSL
                     NSKECHNL"
     gene            complement(2755..4044)
                     /locus_tag="ACGI5H_003846"
     CDS             complement(2755..4044)
                     /locus_tag="ACGI5H_003846"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898029.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="hemolysin family protein"
                     /protein_id="HFG9699517.1"
                     /translation="MRELLKVTLIVMLVLINAFFVACEFAMVKLRSSRIDTMITEGNN
                     NAKRCKIIKDNLNSYLSACQLGITLCSLALGWMGESTVKELILPIVSVFNLSESIIYT
                     ISISISFLIITMMEVVIGELVPKALALYNTEKIMLSTSFLLVGFYKLTYPIIYFFNLS
                     TDLFLKPFGYSQADEVDEPHTGDEIRLLVEESYKSGLIDESEQRLVDNIFEFEEKKIR
                     EIMVPRTDMVCIYESDSEEKILAILKEEGVTRYPVCRKNKDDILGFVHIRDLYNQKIN
                     ENKIELEEILRDIIYISENLTIDKALERIRKEKLQLAIVVDEYGGTSGVVTIEDILEE
                     IVGEIQDEFDKEETHIKKIGAGSYLVDGTESINYINKYFGLDIEHDGFDSIGGWISYM
                     LGSNIKVNQSVTFENYNFTILELDKLRVVKLIIKSVI"
BASE COUNT         1411 a          741 c          379 g         1639 t
ORIGIN      
        1 aattgtaata aaatcgtcaa aacttttttt gatactgtta caaaattgta aaaaaaaaga
       61 aaaaaacgcc aaaaataaat ttctttttag cactttttca tacttataat ttgacatttt
      121 aacacttggt taagtataca ccttacctta acttaaaatt aaatttattt aagaatatat
      181 attataaatt cttatatttt ctaatataaa ctatatacta tcagctggat aaacaatact
      241 actttgtctt cttatctcat ccataatttc cattactatt attgaatttt catgagaatt
      301 tatatttgat tctattttat tgttatttat aagacttata aactctacaa gttcataata
      361 cattccttct atttctctag gcttttcctc tgctttttct tttggaatag atatatcttc
      421 ttctcttcca tctctgtatt taataatagc tttttcaaat agattaagct tttcaattat
      481 tatacttccc tcttctcctt gtatttcaga tggtatataa gaatcagcta ctttagaata
      541 ctgaattatc gcatccatat catcatattg aaatacagct gaaccttctc catccactcc
      601 agtttgaagt atatgagaaa ctgcctttac agtttttgga gcaccaaata aattcaccat
      661 aggatgtata caatacactc ctatatccat taaagctcca tttgacaact cttttttaaa
      721 ggcattttct ataattccat ttttatattt atcatatctt gaagaatact gacaatagct
      781 tccaaaaaat cttcttattt tccctatttt atataagttt tctttaactg ctttaaagtt
      841 tggaacacat gtaattctca tagcttccat aagcaataca ttattatctt tggctgtttt
      901 tatcattgat ttgacttctt ttaaattaga tgctaacgac ttttcacaaa gcacatgttt
      961 tttgtgtttt aaacaagtaa tggtttgctt tgaatgtaat gcatttggag aagctatgta
     1021 tacagcatct atatccttcg atttagccat ttgttctaaa tcatcaaaaa aaatacttgc
     1081 tccatataga gttccaaatt ctctagcttt ttctaaattt ctagaatata cagcaaccaa
     1141 ttcaaagtct ttaaccctag atgcagctct tagaaatata tttgctatat tgcttgtccc
     1201 aacaatacca aatcttattt tacccatcat aaatcactcc ccattttcta cactttattt
     1261 taattttaat aaaaaacttt acaacttata gatatattat aaaataattt tatcaaataa
     1321 aaaagaaagc taattttaaa tgatttcacc attttaacat agctttcttt taactacaat
     1381 ctaaattcaa cttatatttt taaagttatc tttctactat atctttattt cccctcaaaa
     1441 attttatagt aagaatttca tccacaaaca atgttactaa aagtatagtt acaacaattg
     1501 gccaataagg tattataaga ctatataaac tatcaactat atacacttga aaatatctaa
     1561 ctccaataaa tgtcaatata gtccaatata cagaaaactt tagacatact attcctctac
     1621 tattgtactt ataatctgaa taatcccaat agaccttatt aaaatatact ttcataagta
     1681 ttcctgtaat atattctact actgtcggca ctactagaca taataaaagc aatgcaaata
     1741 tattattggg gtcaataaat cttgagacct ctattataat cgacattgca attgcataca
     1801 ttggtttaaa tggaccattt aaaaatccat cttcttgaaa atgcccttgt ttataataac
     1861 tatataagtt ttcaattatc caacctataa aaccatacaa gaaaaaatta aataaaaaat
     1921 ataatagaga acctacatta tccatgaata ttcctcctag ctgtttatac ttattttttc
     1981 tcatattcat ggatttattc taaatcaaag aaattatatt taatttattt aattaatact
     2041 ttatattata gattgtgaca ttctttagag ttcaaacttt ttaggtattc tctaacttcc
     2101 agtaaatttt caagtatctt atgtgattgt gatttaattt gctcatctgg ctcttttaaa
     2161 tctggtacat ttatacatct tataccacca ttgtatgcag cttcaactcc cataggcgaa
     2221 tcctctatga caatacaatt ttggggatta acatttatct ttttagctgc ttttaagaat
     2281 atctcagggt ttggtttaga gtttacaaca tcatctccac aaactatagc atcaaagtaa
     2341 tcttttaaat ttgccttagc taatctcttt actgctcttt ctctctttgt tgatgttgca
     2401 acagccattt tgtatccatt ttcctttaaa aaagagatta gttcattgac tcctaatttg
     2461 ataggagctc ccttcctctc cataaattca atcatatttt tagttttttc gtcatataaa
     2521 tctattattg gtacagaact atcgtatata tctgtaagac cttctattat tcctttacga
     2581 tttcttccca taactgatgt ataaatttcc ttagtcatag tatatccata cttttcaaac
     2641 gtctccatcc aaaattcaag agaaattctc tctgagtcaa acaaaactcc atccatgtca
     2701 aaaataattc cttctacttt ttgcatacaa ttcctccaat attttttgat ataattatat
     2761 tacacttttt atgattaatt ttacaaccct caatttatcc aattctaata ttgtaaaatt
     2821 gtaattttca aaagttacac tttggtttac tttaatattt gaaccaagca tataggatat
     2881 ccacccacct atactgtcaa atccatcatg ctctatatca agtccaaaat acttattaat
     2941 atagttgata gattcagttc catcaactaa gtaagaacct gctcctattt tcttaatatg
     3001 agtctcttct ttgtcaaatt catcttgaat ttctccaact atctcttcta gtatatcttc
     3061 tattgttacc acaccagatg taccaccata ttcatccaca actatagcaa gttgaagttt
     3121 ttcctttctt attctctcaa gagctttatc tatagttaaa ttttcagata tatatataat
     3181 atctctcaat atttcttcta gttcaatttt attttcattt atcttttgat tgtataaatc
     3241 tcttatatgt acaaaaccta atatatcatc tttatttttt ctgcatactg gatatcttgt
     3301 aacaccttcc tcttttaaaa tagctaatat cttttcttca gaatcacttt catatataca
     3361 taccatatca gttctaggaa ccattatctc tctaattttc ttttcttcaa attcaaaaat
     3421 attatcaact aatctttgct ctgattcatc tataagtcca cttttataac tttcttctac
     3481 taatagtctt atttcgtcac ctgtatgggg ttcatcaacc tcatcagctt gtgaatatcc
     3541 aaatggttta agaaataaat cagtacttaa gttgaaaaaa tatattattg gatatgttaa
     3601 cttataaaat cctactaata aaaaagatgt actcaacatt attttttctg tattataaag
     3661 tgctaaagct ttaggaacca actctcctat tacaacctcc atcattgtta taattaaaaa
     3721 agaaatggaa attgatatag tatatataat actttcacta agattaaata cacttactat
     3781 tggtaaaatt aactctttaa ctgtagattc tcccatccaa cctaatgcaa gtgaacaaag
     3841 tgttatacca agttgacatg cagaaagata ggaatttaag ttgtctttta ttattttaca
     3901 tctttttgca ttattattac cttcagttat catggtatca atcctagaac tacgaagttt
     3961 taccatagca aattcacaag ctacaaaaaa agcatttatc aaaacaagca ttactataag
     4021 tgttactttt aataactccc gcataaagta ttggttctta taatgtaaga aatctataag
     4081 aactcaaagt tcccccctta tattaataaa tttaatttat aatatatatt ctatcatatt
     4141 tattaatata tcctacttta ttacaaataa
//
LOCUS       DAYAOO010000170         4063 bp    DNA     linear   BCT 12-OCT-2024
DEFINITION  TPA_asm: Clostridioides difficile isolate ST8-SSI-h139-18
            SAMN40601845-rid21577343.denovo.174, whole genome shotgun sequence.
ACCESSION   DAYAOO010000170 DAYAOO010000000
VERSION     DAYAOO010000170.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN40601845
            Sequence Read Archive: SRR28438827
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 4063)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4063)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-MAY-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-MAY-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002157583.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002157583.1
            Genome Coverage       :: 163x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/11/2024 16:19:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 4,038
            CDSs (total)                      :: 3,963
            Genes (coding)                    :: 3,930
            CDSs (with protein)               :: 3,930
            Genes (RNA)                       :: 75
            rRNAs                             :: 6, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 60
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 33
            CDSs (without protein)            :: 33
            Pseudo Genes (ambiguous residues) :: 0 of 33
            Pseudo Genes (frameshifted)       :: 7 of 33
            Pseudo Genes (incomplete)         :: 25 of 33
            Pseudo Genes (internal stop)      :: 11 of 33
            Pseudo Genes (multiple problems)  :: 8 of 33
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4063
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN40601845-rid21577343.denovo.174"
                     /isolate="ST8-SSI-h139-18"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Denmark"
                     /collection_date="2018"
                     /collected_by="Statens Serum Institute"
     gene            183..1136
                     /locus_tag="ACGI5H_003847"
     CDS             183..1136
                     /locus_tag="ACGI5H_003847"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454520.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="iron chelate uptake ABC transporter family
                     permease subunit"
                     /protein_id="HFG9699518.1"
                     /translation="MKKRYLVIGIIILSYFSLFIGAEDINIMHIFAKNQHKLMIFIMS
                     RIPRLISILIAGVGMSIAGLIMQQISKNKFVSPTTGATIDAAQFGIVICMLLVPTASI
                     FTKTIIAFVFSLVGTFTFMKIIGKLQFKNIIFVPLVGIMFGNIIGSMTDFIAYKYDLS
                     QNVSSWMQGDFSMILKGNYEILYITIPLIILAYIYANKFTVVGMGMDFATNLGLSYKR
                     IVNIGLIIVALVTVCVVVTAGNIPFIGLIVPNIVSLYMGDNIRASIWYTGLLGAIFVL
                     ICDIFGRIIIYPYEISIGLTVGVIGSILFLYLILRRNVNEA"
     gene            1126..2082
                     /locus_tag="ACGI5H_003848"
     CDS             1126..2082
                     /locus_tag="ACGI5H_003848"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430100.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron chelate uptake ABC transporter family
                     permease subunit"
                     /protein_id="HFG9699519.1"
                     /translation="MKLSLNQKIYFVSILLFISMALFIIYGIDMNHLEYALSQRIPKI
                     FAMVLGGGCIAFTTVVFQTITNNQILTPSVLGLDSLYVMIQTIIVFIFGSSSSLIINE
                     NYNFIINVAMMIGASLLLYKTLFEKNKNNIFFLILVGMIFGTLFKSATTFIQVMIDPN
                     EFLALQTSIMASLNNINTNVLLIAFIIIIAIIPFIYDEIKYLDVLSLGKEQAINLGVD
                     FDKAVKKMIILIAILVSISTALIGPMTFLGLLLANITREIFKTYKHTYLISGSMLIGM
                     ITLIIGQFFIQHVFKFDTTLSVVINFIGGIYFIQLLLKGANR"
     gene            2079..2834
                     /locus_tag="ACGI5H_003849"
     CDS             2079..2834
                     /locus_tag="ACGI5H_003849"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729480.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HFG9699520.1"
                     /translation="MIEIKNIFKRYKNKNVVDDVSFSIEKGKITSFIGPNGAGKSTVL
                     SIVTRLIGGDGGEVIIEGKSLTNYSNKELAKKIAILKQSNNITLKLTIRELVGFGRFP
                     YSEGNLTKEDENYIDEAIEYMKLTDIQHKYLDELSGGQRQRAYIAMVIAQDTEYILLD
                     EPLNNLDMNHSVQMMKVLRGLCDELDKTIVLVMHDINFASCYSDNIVALKNGKVEKVG
                     RTDEIVNEKVLEDIYEMNFNIKNINGNRICIYF"
     gene            2926..3891
                     /locus_tag="ACGI5H_003850"
     CDS             2926..3891
                     /locus_tag="ACGI5H_003850"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893211.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="siderophore ABC transporter substrate-binding
                     protein"
                     /protein_id="HFG9699521.1"
                     /translation="MNKKAAIVAAVAIIGLVTVFALGGSKKNESKTSENSNNTMKITH
                     NLGETDVKLNPKKVVVFDYSALDTMDALGVAETLVGLPKASLPASLEKYKDDKYADLG
                     GLKEPDLEGIKSANPDLIIINGRQEDFYEQLSKIAPTISTSKDDKKYLESVKNNIDKI
                     AKIFGVEEKANQEFSKIEKKIETLNKKVTDKNLNALTIMVNEGNLSVFGEESRFSILY
                     NSFGFENKDKNIKESSHGQNITFEYIAKQNPEVMFVIDRGIATGSDVKESSTAKSVLN
                     NDIIKSMDAYKNDNIIYLDSPTWYVNDGGLTSLNKMIDDASKAVN"
BASE COUNT         1640 a          384 c          679 g         1360 t
ORIGIN      
        1 aaattggcgt tcataattta ttaaatttta atgttactag aagtttcaat tctagtaaca
       61 ttttttatgt taaaaacaga tatagatatg tattgacaat gataattatt attgataaac
      121 tataaaagtg aaaatgataa taattttcat tttaattaat aaaagatttt taaggaggga
      181 gaatgaagaa aaggtattta gtcataggaa taataatttt gtcttatttt tctttattta
      241 taggagctga agatataaat ataatgcata tatttgccaa aaatcagcat aaacttatga
      301 tatttatcat gagtagaata ccaagattaa taagtatatt gattgctggt gtaggaatga
      361 gcatagcagg tcttataatg caacagataa gtaagaataa atttgtatca cctacaacag
      421 gtgctacaat agatgcagca caatttggga tagtaatatg tatgctttta gtaccaactg
      481 cctctatttt tacaaagaca ataatagcat ttgtattttc tcttgtaggg acttttacgt
      541 ttatgaaaat aatagggaag ttacaattta aaaatataat ctttgtacca ttagtaggta
      601 taatgtttgg aaatataata gggtctatga cggattttat cgcgtataaa tacgatttga
      661 gtcaaaatgt tagttcttgg atgcaaggtg acttttctat gatacttaaa ggaaattatg
      721 agatattata tatcacaata ccccttataa tattagcata tatttatgca aataaattta
      781 ctgttgttgg tatgggtatg gattttgcga caaacttagg tcttagttac aaaagaattg
      841 tcaatatagg tctgataata gtagcacttg ttacagtatg tgtagtcgtt acagctggta
      901 atatcccttt tataggtcta atagttccaa atatcgtatc cttgtacatg ggtgataata
      961 taagagcaag catatggtat actggtttac ttggagcgat atttgtactt atatgtgata
     1021 tttttggaag aattattatt tatccatatg aaatatctat agggcttaca gttggagtta
     1081 taggaagtat actattcctt tatttaatat taaggaggaa tgtgaatgaa gcttagtctc
     1141 aatcaaaaaa tttactttgt aagtatatta ctattcatat caatggcact ttttataatt
     1201 tatggaatag acatgaatca tttagaatat gcattatcac aaagaatacc aaaaatattt
     1261 gctatggtat taggtggagg atgtatagca tttactactg tagtgtttca aacaattaca
     1321 aacaatcaaa tattaacacc aagtgtacta ggtttagatt cattgtatgt aatgattcaa
     1381 actataatag tattcatatt tggttcaagc agtagtctga ttataaatga aaattataat
     1441 tttattatta atgtagctat gatgattgga gcttcattgt tattatataa gacgttattt
     1501 gaaaaaaata aaaataatat tttcttttta atcctagtag gaatgatatt tggaacctta
     1561 tttaaaagtg caacaacatt tattcaggta atgatagacc ctaatgaatt tttagcttta
     1621 caaactagta taatggcaag tttaaacaat ataaacacta atgtattgtt aatagcattt
     1681 ataataatta ttgccataat accttttata tatgatgaaa taaagtattt agatgtattg
     1741 tcgttaggta aagaacaagc aattaattta ggtgtagatt ttgataaagc agttaaaaaa
     1801 atgataatat taatagcaat tttagtctca atatcaacag cacttattgg acctatgaca
     1861 tttttaggac ttttacttgc taatataaca agagaaattt ttaaaacata taagcataca
     1921 tacttgattt cgggttctat gttgataggg atgattacat tgataatagg tcaatttttt
     1981 atacaacatg tatttaagtt tgatacaact ttaagtgtag taataaattt tataggagga
     2041 atttatttta ttcaattact attaaagggg gcaaatagat gatagagata aaaaatatat
     2101 ttaaaagata taagaataaa aatgttgtag atgatgtctc ttttagtata gaaaagggaa
     2161 agataacatc ttttatagga ccaaatggag ctggaaaaag tacagtacta tcaatagtta
     2221 caagacttat aggaggtgat ggtggagaag taataataga aggaaaaagc ttgactaatt
     2281 atagcaataa agaattagca aaaaaaatag ctattcttaa acaatctaac aatataactt
     2341 taaagcttac aataagagaa ttagttggat ttggaagatt tccatatagt gaaggtaatc
     2401 taactaaaga ggatgaaaat tatattgatg aagcaataga atatatgaag ttgactgata
     2461 tacaacataa gtatttagat gaattgagtg gaggtcaaag acaaagagct tatatagcaa
     2521 tggtaatagc tcaagataca gagtacatat tacttgatga accactgaac aatttggata
     2581 tgaaccattc cgtacagatg atgaaggtac ttagaggtct ttgtgatgaa ttagataaga
     2641 ctatagtatt agtaatgcat gatataaatt ttgcatcatg ttattcagat aatatagttg
     2701 cattaaaaaa tggaaaagtt gaaaaagtag gtcgtacaga tgagatagta aatgaaaaag
     2761 ttttagaaga tatttatgag atgaatttta acattaagaa tataaatgga aatcgaatct
     2821 gtatttattt ttaaaatatt gtatatgaaa ataaacttgc tatatgattt tttataaagt
     2881 ttttaaatta aaataaagat taataggaga gaggaaaata ttgatatgaa taaaaaagca
     2941 gcaatagtag cagcagtagc tattatagga ttagtgacag tgtttgcatt aggtggaagt
     3001 aaaaagaatg aatcaaaaac atcagaaaat tcaaataata ctatgaagat aactcataac
     3061 ttgggagaaa cagatgtaaa attaaatcct aaaaaagtag tggtatttga ttattcggct
     3121 ttagatacaa tggatgcatt aggtgtagct gagactttag taggacttcc aaaagcgagt
     3181 ttaccagcat ccttagaaaa atataaggat gacaagtatg cagatttagg aggattaaaa
     3241 gaaccagatt tagaaggtat aaagtcggca aatccagatt taattataat aaatggaaga
     3301 caagaagatt tttatgagca attgtcaaaa atagcaccaa caataagtac aagtaaagat
     3361 gataagaagt acttagaatc tgttaaaaat aatatagaca aaatagcaaa aatatttgga
     3421 gtagaagaaa aagcaaatca agaatttagt aaaattgaaa agaaaataga aactttgaat
     3481 aaaaaagtaa cagataaaaa tttaaatgct ttaactataa tggtaaatga aggtaattta
     3541 agtgtatttg gtgaagaatc aagatttagt atattataca atagttttgg atttgaaaat
     3601 aaagataaaa atataaaaga atcaagtcat ggacaaaata ttacttttga atatatagct
     3661 aaacaaaatc cagaagttat gttcgttata gatagaggaa tagctactgg cagtgatgta
     3721 aaagaaagct caactgcaaa atctgttttg aacaatgata taataaaatc tatggatgca
     3781 tataagaatg ataatataat atatttagat tcaccaacat ggtatgtaaa tgatggtggt
     3841 ctaacatctt taaataaaat gatagatgat gcttcaaaag cggtaaatta ataatccgat
     3901 ataaccaaaa tgtatttttt ataaaatgat tatcaaataa actaggagtt tttaagaact
     3961 cctagtttat tttttgcata aaaaagatat agtttaaaca ataatattat ctataataag
     4021 ataaatctat tcaaaatcta ataaaatatg aagttatact aga
//
LOCUS       DAYAOO010000171         3956 bp    DNA     linear   BCT 12-OCT-2024
DEFINITION  TPA_asm: Clostridioides difficile isolate ST8-SSI-h139-18
            SAMN40601845-rid21577343.denovo.175, whole genome shotgun sequence.
ACCESSION   DAYAOO010000171 DAYAOO010000000
VERSION     DAYAOO010000171.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN40601845
            Sequence Read Archive: SRR28438827
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 3956)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3956)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-MAY-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-MAY-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002157583.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002157583.1
            Genome Coverage       :: 163x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/11/2024 16:19:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 4,038
            CDSs (total)                      :: 3,963
            Genes (coding)                    :: 3,930
            CDSs (with protein)               :: 3,930
            Genes (RNA)                       :: 75
            rRNAs                             :: 6, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 60
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 33
            CDSs (without protein)            :: 33
            Pseudo Genes (ambiguous residues) :: 0 of 33
            Pseudo Genes (frameshifted)       :: 7 of 33
            Pseudo Genes (incomplete)         :: 25 of 33
            Pseudo Genes (internal stop)      :: 11 of 33
            Pseudo Genes (multiple problems)  :: 8 of 33
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3956
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN40601845-rid21577343.denovo.175"
                     /isolate="ST8-SSI-h139-18"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Denmark"
                     /collection_date="2018"
                     /collected_by="Statens Serum Institute"
     gene            complement(270..1139)
                     /locus_tag="ACGI5H_003851"
     CDS             complement(270..1139)
                     /locus_tag="ACGI5H_003851"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426876.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Nif3-like dinuclear metal center hexameric
                     protein"
                     /protein_id="HFG9699522.1"
                     /translation="MVIIKAIELYKKLDLEFNIKNINDDWSFMNFENDFITPEFRKKY
                     IGLVLDNAQNINKVYTTTFPDKEIIKQVIDKDEKDILIFSHHAMGYIASDEGFPFHDI
                     PLSYMEEMKNRRISFYVLHSPLDNYSDYSTSVSFAKAMGLEIVKPFCKYDDKIEVGVI
                     CKTSLKSIEEIKELIKKSVGHDVKLYDYGDSVLKDGLVAIAAGGGSYPFVAREVAELG
                     INLYITGFTKPLKHFEPVLEFHQIAKDNLINVIGATHYSTEKFACMGMVDYFKNLGLE
                     SEFLQGKYYLEDL"
     gene            complement(1407..1877)
                     /locus_tag="ACGI5H_003852"
     CDS             complement(1407..1877)
                     /locus_tag="ACGI5H_003852"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895702.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HFG9699523.1"
                     /translation="MKYQVSLLAVKDIEVSKKFYKELFEQEIELDLGKNVTFKGGFAI
                     QEDFAWLTGINPDTIIQKSNNMELYFEVDDFDEFIEKLNYYKDVEFVHKPLKHEWQQR
                     VVRIYDPDKHIIEIGESMEVIARRYLSEGYSVEETSKIIQHPIKFVKQCENSKE"
     gene            complement(2747..3136)
                     /locus_tag="ACGI5H_003853"
     CDS             complement(2747..3136)
                     /locus_tag="ACGI5H_003853"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0045892 - negative regulation of
                     DNA-templated transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="BlaI/MecI/CopY family transcriptional regulator"
                     /protein_id="HFG9699524.1"
                     /translation="MTIKKLPQSELKIMKFIWKSDSKVTSRDIVLGMEQKYQWKQTTT
                     LTLLSRLVVKRFLNSQKIDKYTHYEVLIKEKEYIGVETRDFFRNIHDSSIKSLLLSLH
                     ENINLSKDDILLIEEWIKNLKEEEKDV"
BASE COUNT         1318 a          663 c          272 g         1703 t
ORIGIN      
        1 aatatttata ataatctaaa ataaatattt ataaattcta atcaaccgta aataataatc
       61 taaaatacat caaaaaataa actaaaaaat atcgaaaaat aatttaaaag acatcaaaac
      121 taaatcttct aatcagcaat taaaagtcta ttttcttagt ttaaaaaata aagatagatt
      181 ttttcaaaac actggataaa taggtaaaaa aataaacagt tagtaaaata aatttttact
      241 aactgtttat ttttattgtt taatatgtcc tataaatcct ctaagtaata ttttccttgc
      301 aaaaattctg attctaaacc tagattttta aaataatcaa ccatgcccat acacgcaaat
      361 ttttctgtag aataatgagt agcacctata acattaatta aattatcttt tgctatttga
      421 tggaactcta atactggttc aaaatgtttt aaaggcttag taaacccagt aatatataga
      481 tttataccaa gttcagcaac ttctcttgct acaaatggat aacttcctcc ccctgctgca
      541 atagcaacta aaccatcttt taatacagaa tctccataat catacaattt cacatcatga
      601 ccaacagatt ttttaattaa ttccttaatc tcttctattg attttagtga tgttttacat
      661 ataactccta cctcaatttt atcgtcatat ttacaaaatg gtttgactat ttctaaaccc
      721 atagcttttg caaaactaac agaagttgaa tagtcactat agttgtctag tggagaatgt
      781 aatacataaa aagaaattct acgatttttc atctcttcca tataagatag tggtatgtcg
      841 tgaaatggaa aaccttcatc tgatgctatg tatcccattg catgatgtga aaaaattaaa
      901 atatcttttt catctttatc tataacttgc ttaattattt ctttatcagg aaaagtagtt
      961 gtgtatactt tattaatatt ttgagcatta tctaatacta atcctatgta tttttttcta
     1021 aattctggag taataaaatc attttcaaaa ttcataaaac tccaatcatc attaatattt
     1081 ttaatattaa attctaaatc taatttttta taaagttcaa ttgccttaat aataaccact
     1141 cctttataat aatattgaat tactacatat taatatagaa atttccgata ataaacttta
     1201 tacgtttaag tattcctact tcaaattaaa aatattataa atattcaaat ttattaatat
     1261 attttaatat tatatttatt ttttctttat taatattttc tttattttaa tttaatttat
     1321 gacatttgtc aaatactagt cctatatatt atcttgaatt agttctatta caattaattt
     1381 ctactaaata attataattt aaacaatcat tccttactat tttcacactg ctttacaaat
     1441 ttaattggat gttgaattat tttagaagtt tcttctacag agtatccctc agataaatat
     1501 cttctagcta taacttccat agactctcct atctcaataa tatgcttatc cgggtcataa
     1561 atacgcacta ctctttgttg ccattcatgt tttagtggct tatggacaaa ctctacatct
     1621 ttataataat tgagtttttc aataaattcg tcaaaatcat caacctcaaa ataaagttcc
     1681 atattatttg atttttgtat aattgtatct ggattaatcc ctgtaagcca tgcgaagtct
     1741 tcttgtatag caaatcctcc tttaaatgtt acatttttgc ctaagtccaa ttcaatttct
     1801 tgctcaaata attctttata aaattttttt gatacttcaa tatccttcac tgctaataat
     1861 gaaacctgat atttcataaa ttttcctcct aattttttat ttctattttt tcagtatctt
     1921 ctattaacat ttttttctct atctcttcag taccttttat taatccttta tttttacttt
     1981 tttagcatct tctattaaca cttttgtttc tacctattca gtatcttata tcaatctttt
     2041 attttttcaa tatcttctat taacactttt atctctatct attcagtact ttctatcaat
     2101 cttttgtttt tatgttttca atatcttcta ttaacacttt tgtttctacc tcttcagtat
     2161 cttatatcaa tcttttattt tttcaatatc ttctattaac acttttatct ctatctattc
     2221 agtactttct atcaatcttt tgtttttatt ttttcaatat cttctattaa tacttttgtt
     2281 tctacctctt cagtatctta tatcaatctt ttattttttc aatatcttct gttaacactt
     2341 ttatctctat ctctttaata tcttatatta atcctttatt tttatttttt caatatcatc
     2401 attaattcct atttatttta tcatcttaaa tacgaaaaca ctgtgtcata tttgcaaaat
     2461 atatattatc atctatatta aagcttcaca atttatattt aaaaattctc tttaattaca
     2521 ctacctctat ttaaaaagct accttaatta tacttataag taaaggtagc tttttaaatt
     2581 taattaaata gaatatccac tattaattta tatttaattt atttagattc acattatagt
     2641 atcataatcc acttataatc atttgtcata ttacttaagt agactaatat attacataaa
     2701 tacacttaca tacactttat attgatgcta taagaaatac gtttgcttat acgtctttct
     2761 cctcttcttt tagatttttt atccactctt caataagtaa aatatcatct ttgctcaaat
     2821 taatattttc atgtaatgac aacaataaac tttttataga agaatcatga atatttctaa
     2881 aaaaatctct tgtctcaact cctatgtatt ccttttcttt aattaaaact tcataatgcg
     2941 tatatttatc tatcttttga gaatttagaa atctttttac tactaatcta gataaaagag
     3001 tcaaagttgt cgtttgtttc cattgatatt tttgctccat tcctaaaaca atatctctag
     3061 atgttacttt ggaatctgat ttccatataa atttcattat ctttaattct gattgtggca
     3121 acttttttat agtcatgata aaaccttgct actcagaata tagacaagca atatccataa
     3181 taaaattttt cgattaaata catcttatac ggatttatat aagctcagac ttataagata
     3241 tttttcaatc ttaatcctaa atttagctat ttgtacacgg taaatatata taaataatgt
     3301 caaaattctc ttgtattata ttgcttaatt ttatgaaata ttttgtactc agctatctat
     3361 tttggatact tgtccagtag ctctcctttc ttttaaactc tttgatttta aatatttgta
     3421 tttcagtaaa tcctacttcc taaatttttt atttactaca acttattact gaacttccta
     3481 cttcctaaac tttttattta ctacaactta ttactgaact tctcacttac taaatttctt
     3541 acttactata aattataact aaacttccta ctttctaaat ttcttacttg ctacaaatta
     3601 ttactaaact tcctctccct aaatttctta cttgctataa attattacta aacttcctac
     3661 tttctaaatt tcttacttac tataaattat tactaaactt cctactccct aattttctta
     3721 cttactataa attattacta aatttcctac tttctaaatt tcttacttac tacaaattat
     3781 tactaaactt cctactccct aaatttctta cttgctataa attattacta aacttcctac
     3841 tccctaagtt tcttacttgc tacaaattat tactaaactt cctacttcct aaatttctta
     3901 cttgctataa attattacta ctaaacttcc cacttactaa atttcttact tactac
//
LOCUS       DAYAOO010000172         3825 bp    DNA     linear   BCT 12-OCT-2024
DEFINITION  TPA_asm: Clostridioides difficile isolate ST8-SSI-h139-18
            SAMN40601845-rid21577343.denovo.176, whole genome shotgun sequence.
ACCESSION   DAYAOO010000172 DAYAOO010000000
VERSION     DAYAOO010000172.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN40601845
            Sequence Read Archive: SRR28438827
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 3825)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3825)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-MAY-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-MAY-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002157583.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002157583.1
            Genome Coverage       :: 163x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/11/2024 16:19:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 4,038
            CDSs (total)                      :: 3,963
            Genes (coding)                    :: 3,930
            CDSs (with protein)               :: 3,930
            Genes (RNA)                       :: 75
            rRNAs                             :: 6, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 60
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 33
            CDSs (without protein)            :: 33
            Pseudo Genes (ambiguous residues) :: 0 of 33
            Pseudo Genes (frameshifted)       :: 7 of 33
            Pseudo Genes (incomplete)         :: 25 of 33
            Pseudo Genes (internal stop)      :: 11 of 33
            Pseudo Genes (multiple problems)  :: 8 of 33
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3825
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN40601845-rid21577343.denovo.176"
                     /isolate="ST8-SSI-h139-18"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Denmark"
                     /collection_date="2018"
                     /collected_by="Statens Serum Institute"
     gene            465..2276
                     /locus_tag="ACGI5H_003854"
     CDS             465..2276
                     /locus_tag="ACGI5H_003854"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EAL domain-containing protein"
                     /protein_id="HFG9699525.1"
                     /translation="MKKKYDFLIYSAIWLVIIILFIFSLYHSIEHIKIISHTGTIRSE
                     TQKVVKQELNNERNDDLIKRLDNILIKLRTGNGENGFQRCDNKEFQQKLNQMDSMWES
                     MKKEIIKVRNGASGDKLYKLSEEYSVLSNQIVFISEKHSNAKLYSFATALFIYLIFST
                     ISLLIWEYYNKKRFKRIFYTDNLTKIKNQVAFENRAIEILHNASNKEYVLLNIDIDNF
                     KYINDTHGYEYGDKVLIIVATVLSKTFNIKETCARICSDNFVILAKYRDSLLEDIREM
                     LTNAIISELDMNVTQTISYCIGAYLVEIDNLGYKSINSMMDKANIAHKVSKTRGISST
                     VWYNENLLKQLQMENSIYNYMYKAIENEEFHMYLQPKFQISSLNVVSAEALVRWFSPE
                     LGFLSPDEFIPLFEKSGFIIELDFYMLKKACSFVKKTFMKKNQYTYPIAVNFSRVTIY
                     QNSFYQRFLDTVKEYEIPFKYIEIEVTESAFNEISQPVISILEELKKLGFLISMDDFG
                     SGYSSLSLLCSLSINGLKLDKSLLKETFNREKVYSIIQCIIEMSHRIGMSVVCEGIET
                     KKDLEFLNTVKCDVGQGFYFSKPIEEKEFFNKYVTKK"
     gene            complement(2364..2945)
                     /locus_tag="ACGI5H_003855"
     CDS             complement(2364..2945)
                     /locus_tag="ACGI5H_003855"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729118.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9699526.1"
                     /translation="MSYLLKINQFERSYDIGIFKNEQSIYKFIEKIPFVKKDSSNFNY
                     TNYYMEFEAIPEYYEVNFNNYLYIITRFSFIPDGTEIFFTWEEIHCWDEKVATEKTFI
                     NGETLVDSYNFPNNEVKDYIQKRESLYIETKKYYEEKGLKIERHALGSEDGEYVELTN
                     DSILYLLDIEAVEIREQSKNIEEFLYKYKKRFK"
     gene            complement(3381..3587)
                     /locus_tag="ACGI5H_003856"
     CDS             complement(3381..3587)
                     /locus_tag="ACGI5H_003856"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424507.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9699527.1"
                     /translation="MNQSQEKDLEFIKNHWDLTIIEKERNVTRIIRYSLIILAIIAFF
                     LPTKIKFSIYIFISLFCWLMYLVL"
BASE COUNT         1464 a          379 c          521 g         1461 t
ORIGIN      
        1 ggtcttattg cacaaaaata gatataattt aagtaatata ccaaaaaaaa ggaatatatt
       61 tacataatat gataaaataa attcaaagag ttaaattgta ggtaaatagt attttaatta
      121 tttattaaaa tatagattat gtatatgcca aatttaaaaa gagacataaa gacattatac
      181 aaatatatta ttggggtgat attttgtaag aaaagaagtg atgcagtaaa ttaattgagt
      241 aatttaaaaa tgatttaatg ataatgttga tgaatgttta aaaagaaatt ttagaaaaac
      301 gtatattgct gtttgtgttg gaggtgatga atttgtagaa tttatagggt ataaatgatt
      361 aaactattta agataaatac atatcactgt aaaatattga taatcatttt ttataagaga
      421 ttgattattt gcaaattata tatattacaa atgaggtaac aataatgaag aaaaaatatg
      481 attttttaat ttattctgct atttggctag ttattattat tctttttata ttttctctat
      541 atcatagtat agagcatatt aaaattataa gtcacactgg tactattcgc agtgaaactc
      601 aaaaggttgt taagcaagaa ttgaataatg aaagaaatga tgacttgata aaacgactgg
      661 ataatattct gataaagcta agaacaggta atggagaaaa tggatttcaa agatgtgata
      721 ataaagaatt tcaacaaaaa ctaaatcaaa tggattctat gtgggaatct atgaagaaag
      781 aaattataaa agttagaaat ggtgcttcag gtgataaatt atataaattg agtgaagagt
      841 attctgtgtt gtctaatcaa attgttttta tatctgaaaa acactctaat gcaaaattgt
      901 attcttttgc tactgcacta tttatttatc ttatattctc aacaataagt cttttaattt
      961 gggaatatta taataaaaaa aggtttaaaa gaatatttta tactgataat ttaacaaaaa
     1021 taaaaaatca ggttgcattt gaaaacagag cgattgaaat tttgcacaat gcatctaaca
     1081 aagagtatgt actgctaaat attgatattg acaattttaa atatattaat gatacacatg
     1141 gatatgaata tggagataaa gttctaataa tagttgcaac tgttctttct aaaactttta
     1201 atataaaaga aacttgtgca agaatttgtt cagataattt tgtaatactt gcaaaatata
     1261 gagattctct tttagaggat attcgggaaa tgctaactaa tgctataatc tctgaattag
     1321 atatgaatgt aactcaaact atatcttatt gtataggagc ttacttagtt gaaattgata
     1381 atttaggtta taaatctatc aattctatga tggataaggc aaatattgca cacaaggtaa
     1441 gtaaaacaag aggaatttcc tccacagtat ggtataatga aaatctgtta aaacagttac
     1501 aaatggaaaa tagtatttat aattatatgt ataaagcgat agaaaatgaa gaatttcata
     1561 tgtatttgca acctaaattt caaatatctt ctttaaatgt tgtgagcgca gaagctcttg
     1621 taagatggtt ttctccagaa cttggttttt tatcaccaga tgaatttatt ccattgtttg
     1681 aaaaaagtgg atttattatt gaattggact tttatatgtt aaaaaaagcg tgttcatttg
     1741 taaaaaaaac gtttatgaaa aaaaatcaat atacatatcc gattgcagtt aatttttcaa
     1801 gggttactat ttaccaaaat agtttttatc aaaggttttt agatactgtt aaagaatatg
     1861 aaattccttt taagtatata gagatagagg taactgaaag tgcttttaat gaaatatctc
     1921 aaccagttat ttcaatttta gaggaactta aaaagttagg atttttaatt tctatggatg
     1981 attttggatc aggatactct tcattaagtc ttttatgttc tctatctatt aatggattga
     2041 agttagataa aagcttactt aaagaaacat ttaaccggga gaaagtatat agtattattc
     2101 agtgtattat tgaaatgtca catcgtatag gcatgtctgt tgtatgtgaa ggtattgaaa
     2161 ctaaaaaaga cttggaattt ttaaatacag ttaaatgtga tgtaggacaa gggttttatt
     2221 tttctaaacc gatagaagaa aaagaatttt ttaacaaata tgtaactaaa aaataatata
     2281 attattttta tcagtctata cattgagtca ttttatatct cgttaaatga ctcaatgcac
     2341 tgttatgtat tttaaaatat aaattattta aaacgttttt tatacttata tagaaattct
     2401 tctatatttt ttgattgttc tcttatttca actgcttcta tatctagtaa ataaagtata
     2461 gaatcatttg taagttcaac atattcacca tcttctgaac cgagtgcatg tctctcaatt
     2521 tttaatcctt tttcttcata atattttttt gtttctatat ataatgattc tcgcttttgt
     2581 atgtagtctt tcacttcatt atttggaaag ttatatgaat ccactaatgt ttcgccattt
     2641 ataaaagttt tctcggtagc aactttttca tcccaacaat ggatttcttc ccaagtaaaa
     2701 aatatctcag ttccatctgg aatgaatgaa aacctggtaa taatatataa ataattattg
     2761 aaatttactt cataatattc aggaatagct tcaaattcca tatagtaatt tgtataatta
     2821 aagttactac tatctttttt tacaaatggt attttctcaa taaatttata tattgattgt
     2881 tcatttttaa aaattcctat atcatagctt ctttcaaatt gattaatttt taataaatat
     2941 gacatatatt ctccttattt gttgaaatat aatttttata actctactaa ttttaaacat
     3001 ttttaaataa atatttgtat ataccttata taatattata gtaattagtt ttaaatcaat
     3061 agaatagtat gtatttatct aatgcggcaa tataatttaa agctggtgtt gtagaaaaac
     3121 taagagtgaa tatagcaaag agaagcaata gtattttaaa ctttgtctct cttatttttt
     3181 gaaaactaac attaaaacat aaggtataaa taatattatc atataaatga aaacaaattt
     3241 gaatttttct ctggtcgatg tatatagtaa gtttgttgat atgagaaaaa ttattattga
     3301 taatatacat gcatagaaag gaaatggtat ataatatttt cttaagtttc ttttttaggc
     3361 atttctattg gcattttagg ctatagtact aaatacatta accaacaaaa taatgaaata
     3421 aatatatata tagaaaactt aattttcgtg ggaagaaaaa aagcaataat agcaagtatt
     3481 attagagaat aacgaataat acgagtaaca tttctttctt tttctatgat agttaaatcc
     3541 cagtgatttt ttataaattc aaggtctttt tcttgactct gattcattta atcatctcct
     3601 gttaatagta taattttaaa gctattactt tgttttattt taacatattt atacactaaa
     3661 gtgaatttta tgattagatt tatttaatta tttctgaatt aaaacttatt agaattctct
     3721 attttgataa tttcaaactc tattgattgt atgataattg aaactatagg atatgtagga
     3781 taacaagttt caaagtagtt aaaataaaaa agataatgat attat
//
LOCUS       DAYAOO010000173         3818 bp    DNA     linear   BCT 12-OCT-2024
DEFINITION  TPA_asm: Clostridioides difficile isolate ST8-SSI-h139-18
            SAMN40601845-rid21577343.denovo.177, whole genome shotgun sequence.
ACCESSION   DAYAOO010000173 DAYAOO010000000
VERSION     DAYAOO010000173.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN40601845
            Sequence Read Archive: SRR28438827
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 3818)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3818)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-MAY-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-MAY-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002157583.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002157583.1
            Genome Coverage       :: 163x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/11/2024 16:19:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 4,038
            CDSs (total)                      :: 3,963
            Genes (coding)                    :: 3,930
            CDSs (with protein)               :: 3,930
            Genes (RNA)                       :: 75
            rRNAs                             :: 6, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 60
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 33
            CDSs (without protein)            :: 33
            Pseudo Genes (ambiguous residues) :: 0 of 33
            Pseudo Genes (frameshifted)       :: 7 of 33
            Pseudo Genes (incomplete)         :: 25 of 33
            Pseudo Genes (internal stop)      :: 11 of 33
            Pseudo Genes (multiple problems)  :: 8 of 33
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3818
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN40601845-rid21577343.denovo.177"
                     /isolate="ST8-SSI-h139-18"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Denmark"
                     /collection_date="2018"
                     /collected_by="Statens Serum Institute"
     gene            <1..1753
                     /locus_tag="ACGI5H_003857"
     CDS             <1..1753
                     /locus_tag="ACGI5H_003857"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=2
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9699528.1"
                     /translation="RIFMVKSKKKIFVFLILIAVFIIFASYIRNYTNDTKKDSVRGTI
                     PFEKMEYKRPNIQSICENINKCNDKLLTAKTAKEQLNLFNEVDKIYQDFYSTLTIAKI
                     RNNIDSSDEFYSKEYKYLMSKSVDVDMSYKDFQDRFVTSKFSKELEKELGKDTFNYLK
                     NIGKLNSKEVEGLLKKEQDLVVKYEDLLAKSTVSIDGIEVDFEEALSRPNLSPEEYVK
                     IYSDYLKKYNPIFGNIFLELIQTRTEIASKQGFKNYIDYAYMNLNKDYSQEEAKKFRQ
                     DVKDYIVPLYREISSKPSDSSIYIKVYKNRSFRKFDKVLEDISPKLKESFDYMKKYDL
                     YDYSSGKNKSPGGYTTYINKYKAPFLFNTWDNSFLGVTSFAHEFGHFYNYYNSINLNN
                     KMQPSIDVCEVHSTSLEILFYKYFDDFFGKQSEAIKKEHLSIVLNTIIDACLYDEFQE
                     IIYKNPYMSLNDINKLFFDLEEEYGVSNNILREKNAPFWILVSHNFQVPFYYLSYGLA
                     SDVSLQIWQLSQEDYRKAVDVYMDFLNQNTDAGFKDVVEKVNLQLPFQDGNLEEISST
                     LYDYFGIDNPLELKNAS"
     gene            complement(1923..2111)
                     /locus_tag="ACGI5H_003858"
     CDS             complement(1923..2111)
                     /locus_tag="ACGI5H_003858"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418249.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9699529.1"
                     /translation="MKIITIGSSLITVLLFLSTMICGFWIKNNKVTDASSIKFHMNSA
                     IFTGIFLLISTILLIIYI"
     gene            complement(2108..2689)
                     /locus_tag="ACGI5H_003859"
     CDS             complement(2108..2689)
                     /locus_tag="ACGI5H_003859"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895741.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HFG9699530.1"
                     /translation="MKSNDKDARERIIEVTLNLLNEVDDIEEITVRKIAERANVGVGL
                     INYHFKTKDNLLSTAIGDVMSNIIAELYDDSVYTLRPIEDLKNLLKKLCDTGLHYEKV
                     LPFVLNQCITNGDMQAELDIVPMLRKIFGNKKDEMSLRIIALQIILPIQISALSTESF
                     QLYSGINIKNKYERDKFIDILIENIIGEDVDVR"
     gene            2857..3675
                     /locus_tag="ACGI5H_003860"
     CDS             2857..3675
                     /locus_tag="ACGI5H_003860"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003432306.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HFG9699531.1"
                     /translation="MFKIGDFSKLSKISIRMLRHYDEIGLLTPSHTNKTNGYRYYSAD
                     QLSTTNRIHALKDMGFGLYSIKEILTEYNDKESLIKYLNIHHSQVKEQLEDTQKKLLK
                     IETTIKRIGGNDIMKNYDVTIKNFAPKYMMTLRRVIPTYQDEGMLWHQAFLETKDQNV
                     QIEPPKYSKAVFYDTGYKEDYVDVEVQVAVSGKYKDTEHVKFKTVPSVTAATAIVNGN
                     FNQVADACEAIGNWISDNNYDVDGPMFNIYHVSPGNDSNPDNWVTEVCFPVKKK"
BASE COUNT         1461 a          502 c          517 g         1338 t
ORIGIN      
        1 gaggattttt atggttaaat ccaagaagaa aatatttgtt tttctaattt taattgcagt
       61 ttttattata tttgcatcat acataagaaa ttatactaat gatacaaaaa aagattctgt
      121 tagaggaact attccttttg aaaaaatgga atataagcgt cctaatatac agtcaatttg
      181 cgaaaacatt aacaagtgca acgacaaact tttaacagct aaaacagcta aggaacaatt
      241 aaatttattt aatgaagttg ataaaattta tcaagatttt tacagtacac ttactatagc
      301 aaaaattaga aataacatag attcatcaga cgaattttac tctaaggaat ataagtatct
      361 tatgagtaaa tcagtagatg ttgacatgtc atacaaagac tttcaagata gatttgtaac
      421 ttctaaattc tctaaagaat tagaaaaaga acttggaaag gatacattta attatctaaa
      481 gaacattgga aaacttaatt ctaaagaagt tgaaggtttg cttaaaaaag agcaagacct
      541 agttgtaaaa tatgaagact tattagctaa atctacagta tcaatagatg gtatagaggt
      601 agactttgaa gaagccttgt caagaccaaa tcttagccct gaagaatatg tgaaaattta
      661 ttcagattac ttaaaaaaat acaatcctat atttggtaac atattcttag aacttataca
      721 gacaagaact gaaatagcaa gtaagcaagg atttaagaat tatatagatt atgcctatat
      781 gaacctaaac aaagactatt ctcaagaaga agctaaaaaa tttagacaag atgtaaaaga
      841 ttacatagtt ccattatata gagagatttc atctaaacca tctgattctt ctatttatat
      901 taaagtatat aaaaatcgct catttaggaa gtttgataaa gtacttgaag atatatctcc
      961 aaaactaaaa gagagcttcg actatatgaa aaaatatgac ttgtacgatt attcttctgg
     1021 aaaaaacaaa tcacctggag gatatactac ttatataaat aaatataaag cacctttctt
     1081 gtttaataca tgggataatt cttttttagg tgttactagt tttgctcatg agtttggtca
     1141 tttttataat tactacaaca gtattaactt aaacaataag atgcaaccaa gtatagatgt
     1201 atgtgaagtt cattcaacat ctttagaaat tctattttat aaatattttg atgatttttt
     1261 tggtaaacaa tctgaagcta taaaaaaaga acacttatcg attgttttaa atactattat
     1321 tgatgcttgt ctttatgatg aatttcaaga aattatatac aagaatccat atatgagtct
     1381 aaatgatatc aataaattgt tttttgattt agaggaagaa tatggagttt ccaataatat
     1441 acttagagaa aaaaatgctc ctttttggat acttgtatct cataacttcc aagttccttt
     1501 ttattacttg agttatggtc ttgcatctga tgtatcactt cagatatggc aattatcaca
     1561 agaagattac agaaaagctg ttgatgtata tatggatttt ttaaatcaaa atactgatgc
     1621 tggatttaaa gatgtggtag aaaaggtaaa tttacaatta cctttccaag atggaaattt
     1681 agaggaaata agctctactt tatatgatta ttttggtata gataatccgc ttgaactaaa
     1741 aaatgcttct taatttctaa tactttatac tcactcttaa gatttagtat tagattgaaa
     1801 taagtgatat tttttcacac acaattaatg tttaataaaa ttatatggta aagtatcaga
     1861 aatttttaag actcttgtct ttataatttc tgatacttta tttattaata atattattat
     1921 ttttatatat atataattaa aaggattgtg gaaatcaata aaaatatccc tgtaaaaata
     1981 gcactattca tatggaactt aatagaactt gcatctgtta ccttattatt cttaatccag
     2041 aacccacaaa tcatagttga aagaaaaagt aaaacagtga taagacttga accaatagtt
     2101 ataattttca tcttacatca acatcctctc caataatatt ttctattaaa atatcaatga
     2161 atttatctcg ctcatattta ttctttatat ttataccact gtataactga aatgattctg
     2221 tagataaagc agaaatctgt attggtaaaa taatttgcag ggcaataatt cttagactca
     2281 tttcatcttt tttatttcca aaaattttac gaagcatagg gacaatatca agttctgctt
     2341 gcatatctcc attggttata cattgattca atacaaaagg aagcactttt tcataatgta
     2401 atccagtatc acacaatttt tttaataaat tttttaaatc ttcaataggt cttagagtat
     2461 atacactatc gtcatatagc tctgctatta tatttgacat cacatctcct atggcagtac
     2521 tcaacaaatt atcctttgtt ttaaaatgat aatttattaa accaactcca acatttgcac
     2581 gctcagcaat ttttctaact gtaatctcct caatatcatc tacttcattt aaaagattca
     2641 atgtaacttc aattatacgt tctctagcat ctttatcatt acttttcata atagacctcc
     2701 aaaacaatta acattttcag ttctgaacat gttcagtata atattttttt catcatatgt
     2761 caatataatt taattataat tttagttgac tctaacatta tgatatggtt tatattaata
     2821 ttaagctaaa agtaccttta taaaggagac aaaaacatgt ttaagatagg cgatttttca
     2881 aagctaagta aaattagtat tcgtatgtta cgtcattatg atgaaatagg acttttaact
     2941 ccttctcata cgaataaaac taatggatat agatactata gtgcagacca actttctact
     3001 acaaacagaa tccatgcact aaaagatatg ggctttggct tgtattctat aaaagaaatt
     3061 ttgacagaat ataacgataa agaaagtctc ataaaatatc taaatatcca ccattctcaa
     3121 gtaaaagaac aattagaaga tacacagaaa aaactattaa aaatagaaac cactattaaa
     3181 agaattggag gaaatgatat tatgaaaaat tatgatgtaa ctataaagaa ttttgcacca
     3241 aaatatatga tgacacttag aagggttata ccaacttatc aagacgaagg aatgttatgg
     3301 catcaagcat ttttagagac aaaagaccag aatgttcaaa ttgaaccccc aaagtattct
     3361 aaagcagttt tttatgatac tggatataaa gaagattatg tagatgttga agtacaagtt
     3421 gctgtatctg gaaagtataa agatactgaa catgttaaat ttaagactgt tccaagtgtg
     3481 actgctgcaa ctgcaattgt taatggaaat ttcaatcaag ttgcagacgc ttgtgaggct
     3541 attggtaatt ggatatcaga taataactat gatgtggatg gtcctatgtt taatatttat
     3601 catgtaagtc ctggcaacga tagtaatcct gataattggg taacagaggt atgcttccca
     3661 gttaaaaaga agtaattttt atattaattg gataatattt taatttgtta gacaaattac
     3721 ttttagtgtt atgtataaat acctacaatt taattaggat attatcttaa tttgttaaac
     3781 aaattacttt tagtgttatg tataaatatc tacaattt
//
LOCUS       DAYAOO010000174         3743 bp    DNA     linear   BCT 12-OCT-2024
DEFINITION  TPA_asm: Clostridioides difficile isolate ST8-SSI-h139-18
            SAMN40601845-rid21577343.denovo.178, whole genome shotgun sequence.
ACCESSION   DAYAOO010000174 DAYAOO010000000
VERSION     DAYAOO010000174.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN40601845
            Sequence Read Archive: SRR28438827
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 3743)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3743)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-MAY-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-MAY-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002157583.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002157583.1
            Genome Coverage       :: 163x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/11/2024 16:19:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 4,038
            CDSs (total)                      :: 3,963
            Genes (coding)                    :: 3,930
            CDSs (with protein)               :: 3,930
            Genes (RNA)                       :: 75
            rRNAs                             :: 6, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 60
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 33
            CDSs (without protein)            :: 33
            Pseudo Genes (ambiguous residues) :: 0 of 33
            Pseudo Genes (frameshifted)       :: 7 of 33
            Pseudo Genes (incomplete)         :: 25 of 33
            Pseudo Genes (internal stop)      :: 11 of 33
            Pseudo Genes (multiple problems)  :: 8 of 33
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3743
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN40601845-rid21577343.denovo.178"
                     /isolate="ST8-SSI-h139-18"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Denmark"
                     /collection_date="2018"
                     /collected_by="Statens Serum Institute"
     gene            200..1780
                     /locus_tag="ACGI5H_003861"
     CDS             200..1780
                     /locus_tag="ACGI5H_003861"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418630.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional ADP-dependent NAD(P)H-hydrate
                     dehydratase/NAD(P)H-hydrate epimerase"
                     /protein_id="HFG9699532.1"
                     /translation="MLIGTSKLSRNVDTACVEEVGIPMIVLMENAVISAMKNMDIDMY
                     NSYTVVCGVGNNGGDGLGIARHLNTYGKEVNVFLVGNLEKLSECSKINYNVLLNMGIN
                     IININKNDLSEKNYGEENEVDKIIKVEKQNIIKNKNLTIFKDRVSKSDVVVDAIFGTG
                     LKRDITGIFKEVIDIVNDNSKNTYSIDIPSGIDSDNGNVLGTCIRANKTISFEFYKRG
                     FLNYDTSALIGDVVVEKIGVPDFITRKYHDEEFITDKTFVKNNIRRRDKHGFKSDFGK
                     VSIVAGSKGFYGASFIATESAVKSGSGLVTLISSEDVQEKVSIRLTEAMTLNFEEERL
                     NKLLNSSDAIGFGPGMGDNSQTFDKLLKIVENSNCPIVLDADGLNVMKDRCYKFLEWK
                     NRFVITPHLGEMARLTGDSIGYIREHRVDVAKEFAQKYNLVVLLKGYQTVITDGKKTY
                     INPTGNSCMATGGMGDCLLGMITSFIGQGMDILEATVSGAYIHGYIGDKLSKAMYTVN
                     ATDLISNISLTMKELLDI"
     gene            1954..2400
                     /locus_tag="ACGI5H_003862"
     CDS             1954..2400
                     /locus_tag="ACGI5H_003862"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437174.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NfeD family protein"
                     /protein_id="HFG9699533.1"
                     /translation="MKLIWLIVAVLFGIAEMLTPSLTLIWFSVGAVILIFLSSFIESI
                     FLQILIFAVISIAMLVVATKKIVKKDKGYKSNTNLQAMMSKKGIVTEEISPNNTGLVV
                     VEHETWTAISIDGEKIEKGSTVEVLKIEGVKLVVKKVDATVNVTNQ"
     gene            2421..3464
                     /locus_tag="ACGI5H_003863"
     CDS             2421..3464
                     /locus_tag="ACGI5H_003863"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418635.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="SPFH domain-containing protein"
                     /protein_id="HFG9699534.1"
                     /translation="MGTKIVLSIVLIVVVVAISLTCIRVIKQSKVGIIMRLGKFQKVA
                     ETGVHFLIPFLDKMAYVIDLREIVIDFPPQPVITKDNVTMQIDTVVYYKVTDPVRYVF
                     EIANPIAAIENLTATTLRNIIGELDLDETLTSRDIINVKMRTILDEATDKWGIKVNRV
                     ELKNIMPPQDIQVAMEKQMRAERERREAILQAEGNKSAAILQAEGEKQSAILTAEAKK
                     EAMVRVAEGEKESAILVAEGEAEAIRQTAIAKAQGEAEMIKRTQMATAEGLKLVFSAM
                     KEADIDNNILALKSMEALEKMAEGKSTKLVLPSEAVNFLGTFKGIKEVMSDDNKEVLD
                     IKEVLNDNESLKK"
BASE COUNT         1510 a          342 c          698 g         1193 t
ORIGIN      
        1 aaatcaacat aataacttaa attatatggt ataataaatt aaataattgt tttaattcaa
       61 aattttttgt tattttaaat tatttcaaaa ctcttagttt tagtgatttt atttatgata
      121 tttatgggat taaaaagatt tcaatagata tttttggtaa gtatttaaga agtctttaac
      181 tttataggag tgataattta tgctaatagg tacatctaaa ttaagcagaa atgttgatac
      241 tgcatgtgta gaagaagtag ggattccaat gattgtattg atggaaaatg cggttatatc
      301 tgcaatgaaa aatatggata tagacatgta taatagttat acagttgtat gtggtgttgg
      361 aaataatgga ggagatggtc ttggaatagc aagacatcta aatacatatg gaaaagaagt
      421 aaacgtattt ttagtaggta atcttgaaaa actaagtgaa tgctctaaaa taaattacaa
      481 tgtactttta aatatgggaa ttaatattat aaatattaat aaaaatgatt taagtgaaaa
      541 aaattatgga gaggaaaatg aagtagataa aattattaaa gttgagaaac aaaatattat
      601 aaaaaataaa aatttaacaa tttttaaaga tagagtatct aaaagtgatg ttgtagtaga
      661 tgctatattt gggactggat taaaacgtga tataactggt atttttaaag aagttattga
      721 catagtaaac gataatagca aaaatacgta ttctatagat attccttcag gtatagatag
      781 cgataatgga aatgtattag gaacttgtat tagagcaaac aaaacgatta gctttgagtt
      841 ttataaaaga ggttttctaa actatgacac tagcgcactt ataggtgatg tagttgtaga
      901 aaagataggt gttccagatt ttattacaag aaaataccat gatgaagagt tcataactga
      961 taagactttt gtaaaaaata atattagaag aagagataag catggtttta aaagtgattt
     1021 tggaaaagta tctatagttg caggttcaaa aggattttat ggtgcaagtt tcatagcaac
     1081 tgaatctgct gttaagagtg ggagtggact tgtaacatta attagtagtg aagatgtgca
     1141 agaaaaggta tctattagac ttacagaagc aatgacttta aattttgaag aagaaagatt
     1201 aaataaatta cttaattcta gtgatgcaat tggttttggt ccaggtatgg gagataatag
     1261 tcaaacattt gataaattac ttaagatagt agaaaattct aattgcccaa tagtattaga
     1321 tgcagatgga ttgaacgtta tgaaggacag atgttataag tttttagaat ggaaaaatag
     1381 atttgtaatt acacctcatt tgggagaaat ggccaggttg acaggagatt caattgggta
     1441 tataagagaa catagagtag atgttgcaaa agaatttgct caaaaatata atctggtggt
     1501 gcttttaaaa ggttatcaaa ctgtcataac agatggtaaa aaaacatata taaatcctac
     1561 aggaaatagc tgtatggcaa ctggtggaat gggtgattgt ttgcttggaa tgattacttc
     1621 atttataggt caaggtatgg atatattgga agctacagtt agtggagcat atatacatgg
     1681 ctatatagga gataaattga gcaaagcaat gtatacggta aatgctacgg atttaataag
     1741 taacatttca ttaacaatga aagagttgtt ggatatataa ttggtgatat ttgatactac
     1801 tttgtaacaa ttttaacaaa gtatgttgat ataatactat taattaatta atttatttta
     1861 ttgttttgta atttaaattt atattcaaaa acattgtata aacatataat ttatataggg
     1921 ttttataatt catatgaaaa gagggtagat agtatgaagc taatatggtt gatagtagca
     1981 gtcttatttg gaatagcaga aatgttaaca ccaagcttaa cattgatatg gtttagtgta
     2041 ggagctgtaa tacttatatt tttaagtagc tttatagaga gtattttctt acaaatttta
     2101 atatttgcag taatttctat agcaatgtta gtcgtagcta ctaaaaaaat agtaaaaaaa
     2161 gataaaggct ataaatctaa cactaattta caagcaatga tgtctaaaaa aggtattgtt
     2221 acagaagaga tttctccaaa taacacaggt ctagttgtag ttgaacatga aacatggacg
     2281 gctatttcta tagatggtga aaagatagaa aaaggttcta cagtagaagt attaaaaatt
     2341 gaaggggtaa aattagttgt taaaaaagta gacgccacag ttaatgtgac aaaccaatag
     2401 aataaaggag gatttatagt atgggtacta aaattgtttt aagtattgta ttaatagtag
     2461 tagtcgtagc aataagttta acttgtataa gagttataaa acaatctaaa gtaggtataa
     2521 taatgagact tggtaagttt caaaaagtgg ctgaaacagg tgtacatttc ttaataccat
     2581 ttttagataa aatggcatat gtaattgacc ttagagaaat tgtaatagat tttccacctc
     2641 aaccagttat aactaaagat aatgtaacta tgcagattga tacagttgta tattataaag
     2701 ttacagaccc agttagatat gtgtttgaga tagctaatcc aatagctgct attgaaaatt
     2761 taacagctac aacactaaga aatataattg gtgaacttga tttagatgaa acattaacat
     2821 caagagatat aataaatgta aaaatgagaa ctattcttga tgaagcaaca gataaatggg
     2881 gtataaaagt aaatagagta gagttaaaaa atataatgcc tcctcaggat attcaagttg
     2941 caatggaaaa acaaatgaga gcagaaagag aaagaagaga ggcaatactt caagcagaag
     3001 gtaataagtc agctgcaata cttcaagctg aaggtgaaaa acaatctgct atattaacag
     3061 cagaagccaa aaaagaagct atggtacgtg tagcagaagg tgaaaaagaa tctgctatat
     3121 tagtggcaga aggtgaagct gaagctataa gacagacagc tattgctaag gcacaaggtg
     3181 aagctgaaat gataaaaaga actcaaatgg caacagcaga aggtttaaaa ttagtttttt
     3241 cagcaatgaa agaggctgat atagacaata atattctagc attaaaatct atggaagctc
     3301 ttgaaaaaat ggctgaaggt aagtcaacaa aactggtttt accttcagaa gcagttaatt
     3361 tcctaggaac attcaaagga ataaaggaag ttatgagtga tgataacaaa gaagtacttg
     3421 atataaaaga agttttaaat gataatgaat cattaaaaaa ataaaagagt tttgttatca
     3481 taggaaggat atggaaatta aaggtcgaat taattaaata tagcacaaaa atgcacgttg
     3541 aaaagaagag gacttataaa tttttaagtc ttcttctttg tttttattag aaagatgaaa
     3601 ttataaaaat aaattaacag aatttttata caatttatcc tttactaatg taaaaagtgt
     3661 tatataatat tatataaaac atatagcaaa taagcatggt tttagttatt ctatttatat
     3721 tattaatata tatttataaa aat
//
LOCUS       DAYAOO010000175         3675 bp    DNA     linear   BCT 12-OCT-2024
DEFINITION  TPA_asm: Clostridioides difficile isolate ST8-SSI-h139-18
            SAMN40601845-rid21577343.denovo.179, whole genome shotgun sequence.
ACCESSION   DAYAOO010000175 DAYAOO010000000
VERSION     DAYAOO010000175.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN40601845
            Sequence Read Archive: SRR28438827
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 3675)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3675)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-MAY-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-MAY-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002157583.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002157583.1
            Genome Coverage       :: 163x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/11/2024 16:19:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 4,038
            CDSs (total)                      :: 3,963
            Genes (coding)                    :: 3,930
            CDSs (with protein)               :: 3,930
            Genes (RNA)                       :: 75
            rRNAs                             :: 6, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 60
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 33
            CDSs (without protein)            :: 33
            Pseudo Genes (ambiguous residues) :: 0 of 33
            Pseudo Genes (frameshifted)       :: 7 of 33
            Pseudo Genes (incomplete)         :: 25 of 33
            Pseudo Genes (internal stop)      :: 11 of 33
            Pseudo Genes (multiple problems)  :: 8 of 33
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3675
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN40601845-rid21577343.denovo.179"
                     /isolate="ST8-SSI-h139-18"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Denmark"
                     /collection_date="2018"
                     /collected_by="Statens Serum Institute"
     gene            164..1540
                     /locus_tag="ACGI5H_003864"
     CDS             164..1540
                     /locus_tag="ACGI5H_003864"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418253.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Trk family potassium uptake protein"
                     /protein_id="HFG9699535.1"
                     /translation="MKTIVRRLILYADGMRPTQIMVSGFAAIIVIGALLLTLPIASQS
                     GESIGLLNALFTATSAVCVTGLVMVDTATYWSLFGQIVIITLIQIGGLGFMTVATMFS
                     LMARKKIQLRERLLIQESLNQADLSGLVRLTRFVLIITITIEGIGALVLSTVFIPQFG
                     LSKGIWYSVFHAISAFCNAGFDLMGSVSGPFTSLNSYVNNFTVSMTVCALIVLGGLGF
                     PVVLDIVRKRRFSKLNVHSKVVLFSTATLIFVGALFIFLIEFNQKATMADLPLKGKVL
                     SAIFQSVTARTAGFNTLDLATLRESSVFVMIILMFIGASPASTGGGIKTTTLAVLIIT
                     VRSFLSGKSDIEAFERRLAPSTIKKSLGIFVISISAVIFGTLIISITQPNFTLVQSAF
                     EVTSALATVGSSLAGTPNLNALGKIIIIIFMFMGRVGSLTLFMAILSGGRRKSQPIRY
                     AEGKIMVG"
     gene            1851..2522
                     /locus_tag="ACGI5H_003865"
     CDS             1851..2522
                     /locus_tag="ACGI5H_003865"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418257.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0006813 - potassium ion transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TrkA family potassium uptake protein"
                     /protein_id="HFG9699536.1"
                     /translation="MKQYIVIGCGRFGSSVASTMHLLGHQVMAIDKNEDSVQSISDKV
                     THSLIVDVTDEQALRSLGLGNFDVAVVAIGSDIRASIMATLIAKEMGVELIICKAKDE
                     LQAKVLYKIGADRVVFPERDMGVRVAHNLVSDNILDHIELDPEYSIVEIVTPNSWVGK
                     TLIELELRARYEITVLAIKTGKNINVTPSPDEELTAGSILVIIGQNTSITAITSGNKG
                     IIRRR"
     gene            2711..3508
                     /locus_tag="ACGI5H_003866"
     CDS             2711..3508
                     /locus_tag="ACGI5H_003866"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436797.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008173 - RNA methyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:0016740 - transferase activity [Evidence
                     IEA];
                     GO_process: GO:0001510 - RNA methylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TrmH family RNA methyltransferase"
                     /protein_id="HFG9699537.1"
                     /translation="MITNINSKDNEKLKYTRALLKSKNRNKESKFIIEGYRIVMLALE
                     CMANLDYVFINEEFENKKEHVKLLEDLDKKNTKIYKTTNKNFKELVDTENTQGIIGVV
                     SFKKKKLSESINKKDKFVLILDRIQDPGNMGTIIRTADSAGVDAIIALKGCVDIYNPK
                     VIRSTMGSIFDMNIIDASQDETVDMLKSLDFNIVSSYLNTENFYDKIDYGSKVALVIG
                     NEANGINEELVSKSDILVKIPIYGKAESLNAAISSAILMYEIKKYLI"
BASE COUNT         1397 a          405 c          677 g         1196 t
ORIGIN      
        1 taaaaattta aaatattcca aacagaaatt ataaaaatta ctatcattgt ctttatacaa
       61 tatttatact ataatagaat aataatttag aggaaagctc taaaaataaa caaattaagg
      121 gtcttaacag tagtgatttt atgttaagga ggtataaaga aagttgaaaa caatagttag
      181 aagacttatt ctctacgcag atggaatgcg tcctactcaa ataatggtat ctgggtttgc
      241 tgcgattatt gtaatcggag cattgttgtt aacactcccg atagcgtcgc agagtggaga
      301 gagtataggc ttattaaatg ctctatttac ggctacttca gcggtttgtg ttactggtct
      361 agttatggta gatacagcaa cttattggag tttatttgga cagatagtta taataacatt
      421 gatacaaatt ggtggtcttg gatttatgac cgtagccaca atgttttcac ttatggcacg
      481 aaaaaaaata caactaagag aaagattatt aatacaagag tcattaaatc aagctgattt
      541 atcgggactt gtaagactta caagatttgt attaataata accataacaa tagagggaat
      601 aggtgcactg gttttatcaa ctgtctttat tccacaattt ggtttgtcta aagggatatg
      661 gtatagtgta tttcacgcaa tatcagcgtt ttgtaatgcc ggatttgact tgatgggcag
      721 tgtaagtggc ccatttacat cgttaaattc ttatgtaaac aactttacag tatcaatgac
      781 tgtttgcgca cttatagtgc ttggagggct aggattccct gttgtacttg atattgtaag
      841 aaaaagaaga ttttcaaaat taaatgtgca ttctaaggtt gtattgtttt caactgctac
      901 acttattttt gtgggtgcat tatttatttt tcttatagaa tttaatcaaa aagctactat
      961 ggcggacttg cctttaaagg gaaaagtact atcagcaata tttcaatcag taacagcaag
     1021 aactgctggt tttaatacgc ttgatttagc tactttacga gaaagtagtg tatttgtaat
     1081 gataattttg atgtttattg gagcatcacc tgcatcaact ggtgggggta taaaaacaac
     1141 aacactagct gttttaatca ttacagttag aagttttcta tcaggaaaat cagatataga
     1201 agcttttgaa agaagattag ctccatcaac tataaaaaaa tctcttggta tatttgtaat
     1261 cagtatatca gcagttattt ttggaacatt gattatttca ataactcagc ctaattttac
     1321 attagttcaa tcagcttttg aggttacatc agcacttgct acagttggtt caagtttagc
     1381 tggaactcca aacttaaatg ctttaggtaa gattataata ataatcttta tgtttatggg
     1441 tagagttggt tctcttactt tatttatggc tatactttct ggtggtagaa gaaagagtca
     1501 accaatcaga tatgcagaag gtaaaattat ggttggttaa gttaccaagg agtagtataa
     1561 atttataatg ggtttagagt agcactgtaa atctgttgat aaaataaatg agcctagatg
     1621 taattatatg aagaaataaa atcaactaat gaacaaaatt aattaatgaa ataaaaaaac
     1681 agggaaataa aatacaaata aaaaggtaaa tcaaaattaa attaatctgt gtgtataaaa
     1741 ttatatattg tgtataagtt ttgtatgtgt aaagtatata agttttgtat gtgtaaacaa
     1801 ttaatttaag agatattata taaattgtgt attagggagg aagtttcgag atgaagcaat
     1861 atatagtcat tgggtgtggg agatttggaa gttcagttgc gtctactatg catcttttag
     1921 gacatcaagt aatggcaata gacaaaaatg aagattcagt tcaaagtata tctgacaagg
     1981 taacccattc acttatagtg gatgttactg atgagcaagc gttaaggtca ttaggtttag
     2041 gtaactttga tgtagcagta gttgcaatag gttctgatat aagggcatct ataatggcga
     2101 ctcttatagc caaagaaatg ggtgtagagt tgataatatg taaggcaaag gatgaattac
     2161 aagctaaagt tctttataaa attggtgcag atagagttgt atttccagaa agagatatgg
     2221 gagtaagagt tgcacacaat ttagtttcgg ataatatatt agaccatatt gaacttgacc
     2281 cagagtattc aattgttgaa atcgtaactc caaatagttg ggttggcaag acacttatag
     2341 agcttgaatt aagagctaga tatgagataa ctgtacttgc tataaaaaca ggtaaaaata
     2401 taaatgttac accttctcca gatgaggaac ttacagccgg aagtatccta gttataatcg
     2461 gtcaaaatac tagtataaca gcgataacat ctggaaataa ggggataatt agaagaagat
     2521 aatttactat ttaatatata tttaattgca atgaaagcag atagtatcat ataattatga
     2581 atagttatat gatactattt ttttaatcga aggtagtatt tatttgtaag attagataaa
     2641 gagaagttaa attaaaagta aggaggctgt gctaatataa aaatttataa gttattagca
     2701 tttagataaa atgattacaa atataaacag taaggataat gaaaagttaa agtatacaag
     2761 agcactatta aaatcaaaga ataggaataa agagtcaaag ttcataatag aaggatacag
     2821 aatagtaatg cttgcacttg aatgtatggc aaaccttgat tatgtattta tcaatgaaga
     2881 atttgaaaat aagaaagaac atgtaaaact attagaagat ttggataaaa aaaacacaaa
     2941 gatatacaag actactaata aaaactttaa agaattagtg gatacagaaa atactcaagg
     3001 aataataggt gtagtttcat ttaagaaaaa aaaattaagt gaaagtataa ataaaaaaga
     3061 taaatttgta ttgattttag acagaataca agacccagga aatatgggga ctataataag
     3121 gactgctgat tctgctggag tagatgccat aatagcacta aagggatgtg tcgatatata
     3181 caacccaaaa gtaattaggt ctactatggg ttctattttt gatatgaata taattgatgc
     3241 ttcacaagat gaaactgtgg acatgcttaa atcattggat tttaatatag tttcaagtta
     3301 cttaaataca gaaaattttt atgacaaaat agattatggc tcaaaagtag cattggtgat
     3361 aggaaacgaa gcaaatggaa taaatgaaga acttgtatca aagtctgata ttttggttaa
     3421 gatacctata tatggtaaag ccgagtcgtt aaatgctgcg ataagctctg ctatactgat
     3481 gtatgaaata aaaaaatact taatttaatg tattgtaata aatataatgt catgttataa
     3541 tcttgaatta aatagtagag tatcaaaaat agtcaatata tattaaaaaa ataattaaat
     3601 taattatata ttagatgtat attatataaa aaataattga gttaattatg cattagatgt
     3661 atattatata aaaaa
//
LOCUS       DAYAOO010000176         3465 bp    DNA     linear   BCT 12-OCT-2024
DEFINITION  TPA_asm: Clostridioides difficile isolate ST8-SSI-h139-18
            SAMN40601845-rid21577343.denovo.180, whole genome shotgun sequence.
ACCESSION   DAYAOO010000176 DAYAOO010000000
VERSION     DAYAOO010000176.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN40601845
            Sequence Read Archive: SRR28438827
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 3465)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3465)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-MAY-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-MAY-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002157583.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002157583.1
            Genome Coverage       :: 163x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/11/2024 16:19:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 4,038
            CDSs (total)                      :: 3,963
            Genes (coding)                    :: 3,930
            CDSs (with protein)               :: 3,930
            Genes (RNA)                       :: 75
            rRNAs                             :: 6, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 60
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 33
            CDSs (without protein)            :: 33
            Pseudo Genes (ambiguous residues) :: 0 of 33
            Pseudo Genes (frameshifted)       :: 7 of 33
            Pseudo Genes (incomplete)         :: 25 of 33
            Pseudo Genes (internal stop)      :: 11 of 33
            Pseudo Genes (multiple problems)  :: 8 of 33
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3465
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN40601845-rid21577343.denovo.180"
                     /isolate="ST8-SSI-h139-18"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Denmark"
                     /collection_date="2018"
                     /collected_by="Statens Serum Institute"
     gene            254..1522
                     /gene="eam"
                     /locus_tag="ACGI5H_003867"
     CDS             254..1522
                     /gene="eam"
                     /locus_tag="ACGI5H_003867"
                     /EC_number="5.4.3.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430434.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016869 - intramolecular aminotransferase
                     activity [Evidence IEA];
                     GO_function: GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA];
                     GO_function: GO:0051539 - 4 iron, 4 sulfur cluster binding
                     [Evidence IEA];
                     GO_function: GO:1904047 - S-adenosyl-L-methionine binding
                     [Evidence IEA];
                     GO_process: GO:0006536 - glutamate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate 2,3-aminomutase"
                     /protein_id="HFG9699538.1"
                     /translation="MNEQTRISLERAAELKSKIDDYIQARKTINRGLEKEEEINKRKQ
                     KILSILNGTEEDWNNYKWQLSNRITDVDTLSKIITLTKKEKEYIKEVGTQFRWAISPY
                     YLSLIDPEDTCDPIKLLSIPTHIELEDEQEDLDPMGEEYTNPAGCITRRYPDRLIINV
                     TNECAMYCRHCQRRRNIGQQDSHKSKAIIQESIDYIRENEEIRDVLVTGGDALTLKDD
                     YLEWILSQLKEIPHVDYVRLGTRTLVTMPQRITDEFCNMLKKYHPVYINTHFNHPMEI
                     TKESKEACEKLANAGVPLGNQAVLLNGINNDKFVMRCLNQELLKIRVKPYYIFQSKHV
                     KGTKHFNTSVDDGLEIMEYLRGYTSGMAIPTYIVNAPKGGGKTPLLPQYLVSKGTDYV
                     MLRTWEGKVIKMEDEPAVDIKKLIKEQAQD"
     gene            complement(1615..1971)
                     /locus_tag="ACGI5H_003868"
     CDS             complement(1615..1971)
                     /locus_tag="ACGI5H_003868"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890447.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9699539.1"
                     /translation="MKKALISLLVLSCLLLTAPVNESSYADSQKNVPVSQNTKLTQEQ
                     AKELLVKYNNEVDYIYQGNASDFEALKAKNLNGYVFLPDADGDIGYFVNENTSEIYYF
                     HPSGYLELVNQQQNNK"
     gene            complement(2122..3216)
                     /locus_tag="ACGI5H_003869"
     CDS             complement(2122..3216)
                     /locus_tag="ACGI5H_003869"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423290.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0015562 - efflux transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:1905887 - autoinducer AI-2 transmembrane
                     transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="AI-2E family transporter"
                     /protein_id="HFG9699540.1"
                     /translation="MQDKKIYLNIVLTVVVSYILIKVIDNYKYFFGVISLLMSLLTPF
                     IIAFVLAYIFNPLVKFLESKLNFKRIYSLLLTYGVLIVILISFILFTVPSIVNSLADL
                     VAQIPTYIDKTEQFLFDLGKSLQSVDPNTLKEYGDKIMSVMPKFSNLLIGSLGGIFST
                     TFSVGKFIVQFLLGFIICFYILLEKEKFLLFTKKVVYISLGKKYGDFIIELCQSLNLN
                     IGKYFTGKILDSFIVGVLSGIGLYFLKSEYALLFGTLMGVMNMVPYFGPVIGMAPVVI
                     INLFSNPTIALTSLIYLIIIQQVEVTFIEPKIVGGQLGLSPFFTILAVTVGGGFFGIP
                     GMILSAPVMGVIKIYFCEFVNRRHDKIQME"
BASE COUNT         1421 a          446 c          487 g         1111 t
ORIGIN      
        1 aaataattct taaaaataga aaaaattaat catttgttaa aaaaaatgca taatttattg
       61 taatttattg acgaaggttg aaaaatattc ataaatgtgc gaaataacag aaaaaatgca
      121 aaaattaatt caatttcatt tgttataaaa tctatatggc aaaattaaat ctgcctatca
      181 gaatgatata aacacaccag aaaggaggac gctatcaaat aatacaagta gttaactttg
      241 atagcaaaaa attatgaatg aacaaactag aatatcctta gagagagctg ctgaattaaa
      301 atcaaaaatt gatgattata ttcaggctag aaaaacgatt aacagaggtc ttgaaaaaga
      361 agaagagata aataaacgaa aacagaaaat attaagtatc ttaaatggaa ctgaagagga
      421 ttggaataac tacaaatggc aattatcaaa tagaataaca gatgtagata ctttatcaaa
      481 aattataact ctaactaaaa aagaaaaaga atatataaaa gaggttggta ctcaatttag
      541 atgggcaata tctccatatt atttgagtct tatagaccca gaagatacat gtgacccaat
      601 aaaattactg tctataccaa cacatataga gttggaagat gaacaagaag atttggaccc
      661 aatgggagaa gagtatacaa acccagcagg atgtataact agaagatacc cggatagatt
      721 aataataaat gtaacaaatg agtgtgctat gtattgtaga cactgtcaga gaagaagaaa
      781 tattggacaa caagattctc ataagtcaaa agctattatc caagaatcta tagactatat
      841 cagagaaaat gaagaaataa gagatgtact agtaactggt ggagatgctc ttacattaaa
      901 agatgattat ttagagtgga ttcttagcca acttaaagag ataccacatg ttgattatgt
      961 tagattaggt actaggactc ttgttacaat gccacaaaga atcacagatg aattttgcaa
     1021 tatgctaaaa aaatatcacc ctgtatatat aaatactcat tttaatcatc caatggaaat
     1081 aactaaggaa tctaaagaag cttgtgaaaa gttagcaaat gcaggagttc cattaggaaa
     1141 tcaggcagta ttattaaatg gaataaataa tgataaattt gtaatgagat gtttaaatca
     1201 agaattactg aaaataagag taaaacctta ttatatattc caaagtaaac atgtaaaggg
     1261 aacaaaacat ttcaatacat cagtagatga tggtcttgaa atcatggagt atttaagagg
     1321 atatacatca ggaatggcta taccaacata tatagtaaat gctccaaaag gaggcggaaa
     1381 gactcctttg cttcctcaat accttgtatc aaaaggaaca gattacgtta tgcttagaac
     1441 atgggaagga aaagttataa aaatggaaga tgaacctgct gtagatataa agaaacttat
     1501 aaaagaacaa gcgcaggatt aaaaaagtat ttaaagttta taaaaagaaa caactttaaa
     1561 ataaaaagaa aatggatgtc aaatttatat caatttgcat ccatttttta ttagttattt
     1621 attattttgt tgttgattaa ctaattcaag atatccactt gggtggaagt aatatatctc
     1681 agaagtattt tcatttacaa agtaaccaat atcaccatct gcatctggta aaaatacata
     1741 accattaaga tttttagctt ttaatgcttc aaaatcacta gcatttcctt gatatatgta
     1801 atcaacttca ttgttgtatt ttactaaaag ttctttagct tgttcttgag tcaatttagt
     1861 attttggctt acaggaacat tcttttgaga atctgcataa gaagattcat ttactggtgc
     1921 agttaataac aaacaagata aaactaataa agatataagt gcttttttca tactaaaacc
     1981 ctctttcatg tttaattata taagattcat tacttaataa tattgtatgt ttcctataat
     2041 taaatattac cattaaagag aataatatta cagttacaca gctgtaactt ttgattacaa
     2101 aatcgtaatt aaattgtatt tttattccat ttgtatttta tcatgtctac gatttacaaa
     2161 ctcacagaag tatatcttta taacgcccat cacaggagca gatagaatca taccaggtat
     2221 accaaagaat cctccaccaa cagtaactgc taggattgta aagaatgggc taagacctag
     2281 ttgtccacct acgatttttg gctctataaa tgtaacttca acttgttgaa ttattattaa
     2341 gtaaattaaa gaagttaaag caattgttgg attggagaat aaattaatta ttacaactgg
     2401 tgccatacct attactggac caaaatatgg aaccatattc atgacaccca taagtgtacc
     2461 aaataatagt gcatattcag attttaaaaa gtaaagacca attccagaaa gtactccaac
     2521 tataaaagaa tctaaaatct tacctgtaaa gtatttacca atatttaaat ttaagctttg
     2581 acatagttct attataaagt ctccatattt tttacctaag gaaatataaa ctactttttt
     2641 tgtaaacagt aagaattttt ctttttctaa taatatatag aaacaaatta taaaacctaa
     2701 aagaaattgt actataaatt ttccaactga aaatgtagtg ctaaatatcc caccaagtga
     2761 accaataagc aagttactaa atttaggcat tacactcata attttgtcac catactcttt
     2821 taatgtatta gggtcaactg attgtaaact cttgcctaag tcgaataaaa actgctctgt
     2881 tttatctatg tatgtaggaa tttgagcaac taaatcagct aaactattta ctatggatgg
     2941 aactgtaaat aatataaacg aaattagtat aactatgagt acaccataag taagaagtaa
     3001 cgaatatatt ctcttaaaat ttaatttact ttctaagaac tttactagtg ggttgaatat
     3061 atatgctaat acaaatgcta ttataaatgg tgttagtagt gacattaata aacttatcac
     3121 tccaaaaaaa tatttgtaat tatcaataac tttaatcaag atatatgaaa caactacagt
     3181 gagtacaata tttagataaa tttttttatc ttgcaaaata acacaacctt tcttatattt
     3241 attaaattta gatatactta aatctaagtt aaagttaata tttatagctt attatacaat
     3301 aaaaagcagt attaatatag tatgattaat atgaaattat aaatacgtta aaactttatg
     3361 tttatagcta aaataataaa aattatttat attgtgttta tatataatct aaaatgaaaa
     3421 aaagtggtgc ctttgattaa actaagtttt tataatttaa atttt
//
LOCUS       DAYAOO010000177         3456 bp    DNA     linear   BCT 12-OCT-2024
DEFINITION  TPA_asm: Clostridioides difficile isolate ST8-SSI-h139-18
            SAMN40601845-rid21577343.denovo.181, whole genome shotgun sequence.
ACCESSION   DAYAOO010000177 DAYAOO010000000
VERSION     DAYAOO010000177.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN40601845
            Sequence Read Archive: SRR28438827
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 3456)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3456)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-MAY-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-MAY-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002157583.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002157583.1
            Genome Coverage       :: 163x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/11/2024 16:19:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 4,038
            CDSs (total)                      :: 3,963
            Genes (coding)                    :: 3,930
            CDSs (with protein)               :: 3,930
            Genes (RNA)                       :: 75
            rRNAs                             :: 6, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 60
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 33
            CDSs (without protein)            :: 33
            Pseudo Genes (ambiguous residues) :: 0 of 33
            Pseudo Genes (frameshifted)       :: 7 of 33
            Pseudo Genes (incomplete)         :: 25 of 33
            Pseudo Genes (internal stop)      :: 11 of 33
            Pseudo Genes (multiple problems)  :: 8 of 33
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3456
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN40601845-rid21577343.denovo.181"
                     /isolate="ST8-SSI-h139-18"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Denmark"
                     /collection_date="2018"
                     /collected_by="Statens Serum Institute"
     gene            complement(321..542)
                     /locus_tag="ACGI5H_003870"
     CDS             complement(321..542)
                     /locus_tag="ACGI5H_003870"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1659 domain-containing protein"
                     /protein_id="HFG9699541.1"
                     /translation="MEVVSTKNLSSIKLKLDAGFDDKGKAVVKSKSFANVKAEALNED
                     VYAVAEAIASLQENPIVDILKLDSTSLSK"
     gene            1122..1379
                     /locus_tag="ACGI5H_003871"
     CDS             1122..1379
                     /locus_tag="ACGI5H_003871"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437357.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Mor transcription activator family protein"
                     /protein_id="HFG9699542.1"
                     /translation="MKIKVEDIPVQFHAMVEIIGIDKFIEVAKLYGGTNTYIPTYKGL
                     FRYARNRDIVKQFNGVNHNELAIRYNMCVSNIKRILNENSV"
     gene            1848..3086
                     /locus_tag="ACGI5H_003872"
     CDS             1848..3086
                     /locus_tag="ACGI5H_003872"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888414.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conserved phage C-terminal domain-containing
                     protein"
                     /protein_id="HFG9699543.1"
                     /translation="MNKGFYKLNSVVLNFDIKNDVNKIRFNHYIMRKENIQRLQGTLP
                     NGQFYMTVRRAATDLQLSISTISRLVKEFLDLGIIRLVSKGVKGNRSVYSYVSIEFNG
                     SLFDDSKYMELDCVCNDEFIDNSGIEFDCDSKDNSFNGDINVETVHCINEYFSDDDVE
                     HNYNNFHNKDTIKDKAISNISTIKKYIDESFDTNKSENSNLQQESINFNFNDTCNEID
                     KRTNNSIENNQNKRPMRLSDISLLSDKGMTNKKNYFNHNHGIQKGTKSVTKKKESLNK
                     FNKKNIQQSIINMLNKKSGKNFKIDSPISIKLINERLKEGYVLEDFYKVIEVKVAKWK
                     NTIMEMYIRPETLFSYKFESYVNENISMKSQSNVHPCKEGNSNDSSNYIHSDYITYDG
                     SVRERKKYENVRYWNPICEI"
BASE COUNT         1423 a          307 c          522 g         1204 t
ORIGIN      
        1 tgttttgctt gttagtatca gtgtttcaat tgtcaatatt agtattttaa ttgttgactc
       61 tagttattgc tgatatagaa aatatttaat ttatttcaat taattagatt aaagtagggt
      121 agcatctaaa atagctaaca tgtttaagtt gaaatacgtt taatatatta atttttcaaa
      181 gcgttaatat attaaagtta taaccaaaat tgaagttata atctgccaaa tctatagcgt
      241 attaagtgca ttatataact taatctttta tataaagagt taatttttta atttgtaaag
      301 cagagtacgt ttaaaagaca ctatttagat agtgatgtac tatctaattt taaaatatct
      361 acaatagggt tctcttgaag acttgctatt gcttctgcaa cagcataaac atcttcattt
      421 aatgcctctg cttttacatt tgcaaatgat ttacttttaa caactgcctt acccttatca
      481 tcaaaaccag catccaattt tagttttata ctagataaat tttttgttga aacaacttcc
      541 ataaaattac ctcctaaaaa tttaatttca aagatttgtc gactttcttt gttagctata
      601 atactatcat ctaagataat atcggagtta aacagtaatt tctaaagatt ttttgtgtaa
      661 atttttatag gaaaaatttt acttttttgc tgatgaaaaa gtttacaagt tatttgtgaa
      721 gatatgttct tagtgttttg aaatagtatt tgtatatatt catgcttagt tgagatagtt
      781 ttgtatggat tttcatatgt gtagagttaa atgttaggta ctaaagttta tgttaaatta
      841 aatgttaaag cttatgttaa aaattttatt aaatttaatc tgtaaataaa aaagttaaaa
      901 gtccaatatt aacattttac ttttaaacca ttaaaatctt tattaaagct aacaaagtta
      961 taagttatga gaaattttat tgaagttaat acaaaaatta attttaaagc taagaaattt
     1021 tttattagat tcaataaaac taataaatat agtttagtca ataatgtatt aaataaaaac
     1081 tttgttaagt ctataaaaat atcttaaagg aggtgtaact tatgaagata aaagtggagg
     1141 atataccagt tcaatttcat gcaatggtag aaataatcgg aattgataag ttcatagagg
     1201 ttgccaagtt gtatggagga acaaatactt atatacctac gtataagggg ctttttagat
     1261 atgctagaaa tagggatata gtaaaacaat ttaatggagt caaccacaat gaattggcta
     1321 ttagatataa tatgtgtgta agcaatatta agcgaatact caatgaaaat agtgtttaaa
     1381 tataataaaa taatgtttaa acataatgaa aatagccttg ttaaacgtaa gagtaaagac
     1441 aaagaagatg ttttataaag tttttttaga caaattaact aaatttacta cttattaatt
     1501 taaatacatt gtatattcta taaaaaaatt tgttaaatac tggagatata ttgagaatac
     1561 aaagaaaatg gtcgaaaata tttgttggct aaaaaataga taaaatgata caattgcttg
     1621 tataaagggg aaaaataaat aaataaacta tataaataaa gaaatagcaa ttaatatgac
     1681 ataatatatt tataaaatta agaatataaa tagatatttt aagggattag ttgttaaatt
     1741 aggaaatatt aaaaaaaata tatatttata tttaaactat tttgttattt atataaaaat
     1801 acttatctag ttactagcaa ttattagtag aaatggggga aatagagatg aataagggat
     1861 tttacaaatt aaattcagtg gtattgaact ttgatattaa gaatgatgtt aacaagataa
     1921 gatttaatca ttatataatg agaaaagaaa acatacaaag acttcaagga actctgccaa
     1981 acggacaatt ttatatgaca gtgagaagag ctgctacaga tttacaactt tctatttcta
     2041 ctataagtag gcttgtaaaa gagtttttgg atttagggat aataagatta gtgtctaagg
     2101 gtgtaaaagg taatcgttct gtatatagtt acgtaagtat agagtttaat ggaagtttat
     2161 ttgatgatag taaatatatg gaacttgact gtgtatgtaa tgatgaattt attgataata
     2221 gtggcataga gtttgattgt gatagcaaag ataattcttt taatggagat ataaatgtag
     2281 aaactgtgca ttgcattaat gagtatttct ctgatgatga tgtagagcat aattataaca
     2341 atttccataa caaagatact ataaaggata aagccatttc taatattagc actatcaaaa
     2401 aatatattga tgaatctttt gatacaaata aatcagaaaa ttctaactta caacaggagt
     2461 caataaattt caactttaat gatacatgca atgaaataga taaaagaacg aataatagta
     2521 tagaaaataa tcaaaataaa aggcctatga gattgagtga catcagtctt ttaagtgata
     2581 aaggtatgac aaataaaaag aattacttta atcataatca tggtatacaa aaagggacta
     2641 aatctgtaac aaagaaaaaa gaatccttaa ataaatttaa taaaaaaaat atacagcaaa
     2701 gcattataaa tatgctaaat aaaaaatcag gtaagaattt taaaatcgat tctccaataa
     2761 gcataaaact tatcaatgaa aggctaaagg aaggctatgt cttagaagat ttctacaaag
     2821 ttattgaggt aaaagtggct aagtggaaaa ataccataat ggaaatgtat ataagaccag
     2881 aaactttgtt tagctataag tttgaatcct atgtaaatga aaacatatct atgaaaagtc
     2941 aaagtaatgt tcacccatgt aaagaaggca atagtaatga tagcagtaat tatatacatt
     3001 ctgattatat aacatatgat ggcagtgtgc gtgagagaaa aaaatatgag aatgtaagat
     3061 actggaatcc tatatgtgaa atttaattag tttaaaaatg tatttatgat aaataagata
     3121 ttaatagaga atagtgagct atagcaaatg atatatcaat agttggtagt aagttatatt
     3181 aagtaagata ttactatcag gtagtgaatt atattgaacg atatattaat aattggcagt
     3241 aagttatatc aaataagata ttactataga gtaatgaatt atattgaacg atatattaat
     3301 aattggcagt aaattatatt aaataagata ttactataga gtaatgaatt atattggacg
     3361 atatatcaat agttggtagt aagttatatt aagcaagata ttactatcag gtagtgaatt
     3421 atattgaacg atatatcaat aattggtagt aaatta
//
LOCUS       DAYAOO010000178         3438 bp    DNA     linear   BCT 12-OCT-2024
DEFINITION  TPA_asm: Clostridioides difficile isolate ST8-SSI-h139-18
            SAMN40601845-rid21577343.denovo.182, whole genome shotgun sequence.
ACCESSION   DAYAOO010000178 DAYAOO010000000
VERSION     DAYAOO010000178.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN40601845
            Sequence Read Archive: SRR28438827
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 3438)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3438)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-MAY-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-MAY-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002157583.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002157583.1
            Genome Coverage       :: 163x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/11/2024 16:19:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 4,038
            CDSs (total)                      :: 3,963
            Genes (coding)                    :: 3,930
            CDSs (with protein)               :: 3,930
            Genes (RNA)                       :: 75
            rRNAs                             :: 6, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 60
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 33
            CDSs (without protein)            :: 33
            Pseudo Genes (ambiguous residues) :: 0 of 33
            Pseudo Genes (frameshifted)       :: 7 of 33
            Pseudo Genes (incomplete)         :: 25 of 33
            Pseudo Genes (internal stop)      :: 11 of 33
            Pseudo Genes (multiple problems)  :: 8 of 33
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3438
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN40601845-rid21577343.denovo.182"
                     /isolate="ST8-SSI-h139-18"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Denmark"
                     /collection_date="2018"
                     /collected_by="Statens Serum Institute"
     gene            complement(415..597)
                     /locus_tag="ACGI5H_003873"
     CDS             complement(415..597)
                     /locus_tag="ACGI5H_003873"
                     /inference="COORDINATES: protein motif:HMM:NF015898.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0045892 - negative regulation of
                     DNA-templated transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="BlaI/MecI/CopY family transcriptional regulator"
                     /protein_id="HFG9699544.1"
                     /translation="MLNKKLPDTELKIMKCIWHTGYKTVISKDVADEIEKTYGWKHTT
                     TIILLARLTKKGFLIS"
     regulatory      823..920
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF01051"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="cyclic di-GMP riboswitch class I; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /bound_moiety="cyclic di-GMP"
                     /db_xref="RFAM:RF01051"
     gene            975..1151
                     /locus_tag="ACGI5H_003874"
     CDS             975..1151
                     /locus_tag="ACGI5H_003874"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9699545.1"
                     /translation="MFGNKMDKCTHVLTAYISSSYDYCNFLDTQLDDFILEYGENVVE
                     SCLHQVMVLVSKYN"
     gene            1377..1577
                     /locus_tag="ACGI5H_003875"
     CDS             1377..1577
                     /locus_tag="ACGI5H_003875"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011723062.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005829 - cytosol [Evidence IEA];
                     GO_function: GO:0001072 - transcription antitermination
                     factor activity, RNA binding [Evidence IEA];
                     GO_function: GO:0003676 - nucleic acid binding [Evidence
                     IEA];
                     GO_function: GO:0003723 - RNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cold-shock protein"
                     /protein_id="HFG9699546.1"
                     /translation="MNNGIVKWFNNEKGFGFISMEGRDDVFAHFSAIQTSGFKSLEEG
                     QQVSFDIVKGARGPQAENITIL"
     gene            2582..3427
                     /locus_tag="ACGI5H_003876"
     CDS             2582..3427
                     /locus_tag="ACGI5H_003876"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipoprotein"
                     /protein_id="HFG9699547.1"
                     /translation="MNIIKSITLLLTLLIVILMTGCSPRESASEVAKKYIDKMNSGDY
                     ETAYSLLSKDSKKKISIENLEEFQNILVSTKRIISYKIGKEKIIKKYKHDGKEYKNVV
                     KLEETFNIKNLLYKKDDSLKVNRYFVVENNKYKLLLYESFKKEFGINSMDLAQLKLND
                     FGLKYFKEVDLILKKAIAINPTDSKLYYAQACNYMNFDGFPGYSDTTYNALDSINKSL
                     KYLDKNDSDYKKNASNIYNLKGVILMFHKRFDEAQQYLNKALYFNKDNEDPKYNLNTI
                     KKHLN"
BASE COUNT         1310 a          409 c          422 g         1297 t
ORIGIN      
        1 agacagtaat ttatctatag tgttacttat attttatata tatggctatt tttcaacatt
       61 ttacaatata taacatttat ttttttaact tttgtcagta aaatgtcagc aaaacacttt
      121 atccacaatt tttatataag ttttccacaa cttatcacca atattatcca cataaaaaag
      181 gtagcactta tattattagc taccttttat ttattaatct ttatatttcc agctttttat
      241 ccaacttcct atttctatta ttttttcttc agttatttct tctccatcat gtaattttga
      301 aattaattct gataaaggat tgttatgtaa acctctaaaa actctttttc cctctatttt
      361 gagatattct ctctctttta ttaatactgt atagtgtaca tgcctcccaa ttctctatga
      421 tattaaaaaa ccttttttgg ttaatctagc taaaagtata attgtagttg tatgcttcca
      481 accatatgtt ttttctattt catctgcaac atcttttgat attacagttt tataaccagt
      541 atgccatatg catttcataa tttttaattc tgtatctggt aattttttat ttagcataat
      601 atattccttc tttcaattta tgtcacttct tcaaatttat ctagcttaaa ttataatagg
      661 agctttttag aacaaaaact atatttaatt tttaccaggt actctacgtg tttagtctgt
      721 ttttaagtgt aaaataatgt tcatatctat aaatttattt aactttcaaa caatcctgtt
      781 gaataataac taattctatt gtattatttt agttgtagaa taaaactaaa tcggcaaaac
      841 tagagaaatt tagtgacgca aagctatagg gactaagact tatataaata tcttatgagt
      901 tatgtcagcc agttgccaaa gagatagtgt tctttttgtt tttatgaaag ttttttaggg
      961 ggataataat ttatatgttt ggaaataaaa tggataaatg tacacatgta ttgactgctt
     1021 atattagcag ttcgtatgat tattgtaatt ttttagatac acagttagat gattttatat
     1081 tagagtacgg agaaaatgta gtagagtctt gtttacacca agtaatggta ttggtaagta
     1141 agtataatta gatagacatt gatttctaga aaaccctttt tagttttatc tacatttata
     1201 ttaatatata gcaatgtaaa acgtttaaat atatttttaa tattaagaat aattaaaatg
     1261 ttaactaaaa aatataatta agtagacatt tctattaatc tatgatacaa tagtatttgt
     1321 ggtaatacac aattaaatca agtatatctt gatataggtt aataggagta tttttaatga
     1381 ataatggaat agtgaaatgg tttaataatg aaaaaggatt cggttttata tcaatggaag
     1441 gtagagatga tgtgtttgct catttctcag ctatacaaac ttcaggattt aaatcattag
     1501 aagaaggtca acaagtaagc tttgatatag ttaaaggtgc tagaggtcct caagcagaaa
     1561 atataactat attataatat atagattttt cgggaaagac tctttttaga gtcttttttt
     1621 attgttaata tatgtaagat aatcattggt gaagtaaata aggtatattg agtaatgttc
     1681 ttgatagttt atatgctaat gaatttcaaa aaaataagca ctcctataaa aagagtgctc
     1741 ttaatgtaaa tataaacctt cattggtcca gcctaatacc ccgtattctc caagttctaa
     1801 ctatttttta tatacattat cactttcatc catatctaac acaattattt cttctttaga
     1861 atcaatttgt aaaatatgag gactgtgtgt tgtgacaatt atttgtgttt ttaggagaat
     1921 tgcttttaat gtaataaaaa ttttacatac cacatagttg atataaaact ataataatta
     1981 cataagattg taataataag acttatcttt acataccaca tagttgatat aaaacaatga
     2041 aattaacata caagagacta agacaattaa aatctttaca taccacatag ttgatataaa
     2101 accccaaaat aaacttagca tctccaatgt ttacacatat acaatgctct taaaattgca
     2161 gtgaacgcgc aatagtgcaa ttgataatac ttattatata ttctcaatgc cttatatttc
     2221 aactgctaaa cctcaatttg tcacaaatat cgctcactgc aaaatttcta tatttttatt
     2281 atatcataac atataattaa tattttcaat taatttttac atttaattat gtttaaattc
     2341 tataataatg caactttaat gtttctttct ggaactaata taaaaactat ttcagaaaga
     2401 ttaggtcatg cagatataaa aataactatg aatagctact ctcagttttt agaagagatg
     2461 gacagagaag catttgaaaa tttgagcaaa atactattta ttatatttta aagaagatga
     2521 cttattcaat atttgatgct agaatataat taataaaaat ttaattatag gtgattgtat
     2581 tatgaatatt attaaaagca taactttact cttaacatta ttaattgtga tattaatgac
     2641 aggctgttcc ccaagagaaa gtgctagtga agttgcaaaa aaatatattg ataagatgaa
     2701 ctctggtgac tatgaaacag catatagttt attaagtaaa gatagtaaaa aaaaaattag
     2761 tatagaaaat cttgaagaat ttcaaaatat tttagttagt acaaaaagaa taattagtta
     2821 taaaataggt aaagaaaaaa tcataaaaaa atataaacat gatggaaaag aatataaaaa
     2881 tgttgttaaa ttagaagaaa cttttaatat aaaaaacctt ctttataaaa aagatgattc
     2941 tctaaaagta aatagatatt ttgtagttga aaataacaaa tacaagctat tattgtatga
     3001 aagtttcaaa aaagaatttg gtattaatag tatggacctt gctcaactta agcttaatga
     3061 ttttggacta aaatacttta aagaagttga ccttatacta aaaaaagcta ttgctattaa
     3121 tcctactgat tcaaagcttt attatgccca agcatgtaat tatatgaatt ttgatggatt
     3181 tcctggttat tcagatacaa catataatgc tttagattca attaataaat ctttaaagta
     3241 tttagataaa aatgattctg actacaaaaa aaatgcaagt aatatatata acttaaaagg
     3301 agttattctt atgtttcaca aaagatttga tgaagcacaa caatatttaa ataaagcctt
     3361 atactttaac aaagataatg aagacccaaa atataatcta aatacaataa aaaaacatct
     3421 aaactagata tttaattt
//
LOCUS       DAYAOO010000179         3295 bp    DNA     linear   BCT 12-OCT-2024
DEFINITION  TPA_asm: Clostridioides difficile isolate ST8-SSI-h139-18
            SAMN40601845-rid21577343.denovo.183, whole genome shotgun sequence.
ACCESSION   DAYAOO010000179 DAYAOO010000000
VERSION     DAYAOO010000179.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN40601845
            Sequence Read Archive: SRR28438827
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 3295)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3295)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-MAY-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-MAY-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002157583.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002157583.1
            Genome Coverage       :: 163x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/11/2024 16:19:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 4,038
            CDSs (total)                      :: 3,963
            Genes (coding)                    :: 3,930
            CDSs (with protein)               :: 3,930
            Genes (RNA)                       :: 75
            rRNAs                             :: 6, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 60
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 33
            CDSs (without protein)            :: 33
            Pseudo Genes (ambiguous residues) :: 0 of 33
            Pseudo Genes (frameshifted)       :: 7 of 33
            Pseudo Genes (incomplete)         :: 25 of 33
            Pseudo Genes (internal stop)      :: 11 of 33
            Pseudo Genes (multiple problems)  :: 8 of 33
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3295
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN40601845-rid21577343.denovo.183"
                     /isolate="ST8-SSI-h139-18"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Denmark"
                     /collection_date="2018"
                     /collected_by="Statens Serum Institute"
     gene            496..3138
                     /gene="adhE"
                     /locus_tag="ACGI5H_003877"
                     /gene_synonym="adhC"
     CDS             496..3138
                     /gene="adhE"
                     /locus_tag="ACGI5H_003877"
                     /gene_synonym="adhC"
                     /EC_number="1.1.1.1"
                     /EC_number="1.2.1.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004022 - alcohol dehydrogenase (NAD+)
                     activity [Evidence IEA];
                     GO_function: GO:0016620 - oxidoreductase activity, acting
                     on the aldehyde or oxo group of donors, NAD or NADP as
                     acceptor [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0006066 - alcohol metabolic process
                     [Evidence IEA];
                     GO_process: GO:0015976 - carbon utilization [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional acetaldehyde-CoA/alcohol
                     dehydrogenase"
                     /protein_id="HFG9699548.1"
                     /translation="MEKKEKVVEKSNVEVCSPEIVNSVETLRMRLEEIRLAQKEFATF
                     TQEQVDKIFLAASTAANQQRIPLAKMAVEETGMGIVEDKVIKNHFASEYIYNAYKDTK
                     TCGVIEKDEAFGFTRIAEPVGVLSAVIPTTNPTSTAIFKSLIALKTRNGIIFSPHPRA
                     KNCTIEAARVVHDAAVKAGAPKGLIGWVDVPSIELTNVVMAEADLILATGGPGMVKSA
                     YSSGKPAVGVGPGNVPAIIDESADIKMAVSSILVSKSFDNGMICASEQAVIVPEKIYE
                     EVKKEFKYRGAHFLNKEETEKVGKVVIIDGSLNARIVGQPAHVIAKMADVEVPKTARI
                     IIGEVESVELNEPFAHEKLSPVLAMYKSKSFEDAVAKAEKLVADGGYGHTSSLYADSI
                     NHPERVEKFVNAMKTCRVLVNTPSSQGGIGDLYNFKLAPSLTLGCGSWGGNSVSENVG
                     VKHLLNIKTVAERRENMLWFRAPEKVYFKKGCLGVAAREFKDVMDKKKAFIVTDSFLY
                     NNGYTKKLTDLLDEMGIKHTTFFDVAPDPTLACAREGAKAMADFQPDLIIAVGGGSAM
                     DAGKIMWVMYEHPEVDFQDLAMRFMDIRKRVYVFPKMGEKAYFAAIPTSAGTGSEVTP
                     FAVITDQDSGVKYPLADYELMPNMAIIDADMMMEMPPRLTAASGVDALTHALEAYVSM
                     LRTEPADGLALQAGKIIFEYLPRAYKNGKNDKEAREKMAMASTMAGMSFANAFLGICH
                     SLAHKLGAFHHVQHGVANALLINEVIKFNCAEAPNKMGAFSQYRYPDCIQRYAEFASF
                     AGIKGSTDQEKVDNLIKAIDELKAKVGLPKTIKEAGVEESKFLERLDAMVEQAFDDQC
                     TGANPRYPLMSELKEIYLKVYYGK"
BASE COUNT         1281 a          412 c          626 g          976 t
ORIGIN      
        1 tgacttaaaa ataacttata gagattagaa taattttagt ttatatattt tttaaaacta
       61 tacagttgtt ataaaaagaa aaattgcata caagtcaaaa ataagtgtta ttttataaaa
      121 atacgacaaa aattttattt actacttata caaataacat gcaaataaca tataaaattt
      181 aataagtaaa aaaaatgaaa gatataaatt atcattttag tattttattt agtcgaagta
      241 aattattcaa atgaaatata tctcatttag ataaaaaatt ttagtaaaag taaaaaaaat
      301 aatatatttg ttaaaaaata aattgacaaa atattcagaa aaaaacttct tgacctaaga
      361 gagtaaaata aataaaatct aaggtataga gatgaaatct ataaaattat tttaagtata
      421 agttaaaaat atagatgatg catttaagat ttataaaaat tagagatgca taattatttt
      481 agggaggttt ttagtatgga gaaaaaagaa aaggtagtag aaaaatcaaa tgttgaagta
      541 tgtagtcctg aaattgtcaa cagtgttgaa acattaagaa tgagattaga agaaattaga
      601 ttggcacaaa aagaatttgc aacatttacg caagaacagg tagataagat tttcttagct
      661 gcttcaactg cagctaatca acaaagaata cctctagcaa aaatggcagt ggaagagact
      721 ggtatgggta ttgttgaaga taaggttata aaaaaccatt ttgcctcaga atatatctat
      781 aatgcttata aagatactaa aacttgtggt gtcatagaaa aagatgaagc atttggtttt
      841 acaagaattg ctgagccagt aggtgtttta tcagcagtta taccaacaac taatcctaca
      901 tcaactgcaa tattcaaatc cctaatagca ctaaaaacta gaaatggtat aattttctct
      961 cctcatccaa gagctaaaaa ctgtactata gaagcagcta gagttgtaca tgatgcagca
     1021 gttaaggcag gagcaccaaa aggacttata ggttgggtag atgttccttc gattgaatta
     1081 actaatgttg tcatggcaga ggcagacctt atattagcta ctggtggacc tggaatggtt
     1141 aaatctgcat actcttcagg taaaccagct gtcggagttg ggcctggaaa tgtacctgca
     1201 ataatagatg agagtgcaga tataaaaatg gctgtaagtt caatcttagt atcaaaatca
     1261 ttcgataatg gtatgatatg tgcttccgag caagctgtaa tagtaccaga aaaaatatat
     1321 gaagaagtta aaaaagaatt taaatatcgt ggagcacatt tcctaaataa agaagaaact
     1381 gaaaaagtag gaaaagtagt aataattgat ggttcattaa atgccagaat agttggacaa
     1441 ccagcacatg taatagccaa aatggcggat gtagaagttc caaaaacagc tagaataata
     1501 attggtgaag tagaatctgt tgaattaaat gaaccttttg cacatgaaaa actttctcct
     1561 gtacttgcaa tgtacaagtc taaaagtttt gaagatgcag ttgctaaagc agaaaaatta
     1621 gttgcagatg gaggctatgg tcatacatct tcattatatg cagactctat aaatcatcca
     1681 gagagagtag aaaagtttgt aaatgctatg aagacttgta gagtattagt taatactcca
     1741 tcatcacaag gtggtatagg tgatttatat aactttaaat tggcaccgtc tcttactctt
     1801 ggttgtggtt cttggggtgg aaactcagta tctgaaaacg ttggagtaaa acatttgctt
     1861 aatatcaaga cagtagctga aaggagagag aatatgcttt ggttcagagc accagaaaag
     1921 gtttatttca aaaaaggatg tttaggtgta gcagcaagag aatttaagga tgttatggat
     1981 aaaaagaaag catttatagt aacagattct ttcctatata ataatggata tactaagaaa
     2041 ttaactgatt tattagatga gatgggaatt aagcatacta cattctttga tgtagctcca
     2101 gacccaacat tagcttgtgc aagagaagga gctaaagcta tggctgattt ccaaccagat
     2161 ttaataatag ctgtaggtgg aggaagtgca atggatgctg gtaagataat gtgggtaatg
     2221 tatgagcatc cagaagtaga tttccaagac ttagctatga gatttatgga tataagaaaa
     2281 agagtatatg tatttcctaa gatgggtgaa aaagcgtatt ttgctgctat cccaacttca
     2341 gcaggaactg gttcagaagt aactccattt gcagttataa ctgaccaaga ttcaggtgta
     2401 aagtacccat tagcagatta tgaattaatg ccaaacatgg ctataattga tgctgatatg
     2461 atgatggaga tgccaccaag attaacagca gcatcaggtg ttgatgcttt aacacatgca
     2521 ttagaagcat atgtatctat gttaagaact gaaccagctg acggtctagc actacaagca
     2581 ggtaaaataa tatttgaata tttacctcgt gcatataaaa atggaaagaa tgataaagaa
     2641 gcaagagaaa aaatggcaat ggcatctact atggcaggaa tgtcttttgc aaatgccttc
     2701 ttaggaatat gtcactcttt agcacataaa ttaggtgcat tccaccatgt tcaacacggt
     2761 gttgcaaatg cattattaat aaatgaagta atcaagttca attgtgcaga agctccaaat
     2821 aagatgggtg cattctcaca atacagatat cctgattgca tacaaagata tgctgaattt
     2881 gcttcttttg caggtattaa aggaagtaca gaccaagaaa aagtagataa tcttataaaa
     2941 gcaatagatg aactaaaggc aaaagtaggt cttcctaaga ctataaaaga ggctggagta
     3001 gaagaatcta aattcttaga aagattggat gctatggttg aacaagcttt tgatgaccaa
     3061 tgtacaggtg ctaatcctag atacccattg atgagtgaat taaaagagat atatctaaaa
     3121 gtttattatg gtaaataata tctattgtgc aacataggtt ctattgggtt tgtatataaa
     3181 ttattagatt tgaatataaa tagagtttta ttagagacac gtagaagtaa ctataaataa
     3241 tagattataa tttaaattct aaatggaaat gataaaaagt cagtaattta atggt
//
LOCUS       DAYAOO010000180         3118 bp    DNA     linear   BCT 12-OCT-2024
DEFINITION  TPA_asm: Clostridioides difficile isolate ST8-SSI-h139-18
            SAMN40601845-rid21577343.denovo.184, whole genome shotgun sequence.
ACCESSION   DAYAOO010000180 DAYAOO010000000
VERSION     DAYAOO010000180.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN40601845
            Sequence Read Archive: SRR28438827
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 3118)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3118)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-MAY-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-MAY-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002157583.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002157583.1
            Genome Coverage       :: 163x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/11/2024 16:19:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 4,038
            CDSs (total)                      :: 3,963
            Genes (coding)                    :: 3,930
            CDSs (with protein)               :: 3,930
            Genes (RNA)                       :: 75
            rRNAs                             :: 6, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 60
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 33
            CDSs (without protein)            :: 33
            Pseudo Genes (ambiguous residues) :: 0 of 33
            Pseudo Genes (frameshifted)       :: 7 of 33
            Pseudo Genes (incomplete)         :: 25 of 33
            Pseudo Genes (internal stop)      :: 11 of 33
            Pseudo Genes (multiple problems)  :: 8 of 33
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3118
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN40601845-rid21577343.denovo.184"
                     /isolate="ST8-SSI-h139-18"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Denmark"
                     /collection_date="2018"
                     /collected_by="Statens Serum Institute"
     gene            715..1590
                     /locus_tag="ACGI5H_003878"
     CDS             715..1590
                     /locus_tag="ACGI5H_003878"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012816033.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HFG9699549.1"
                     /translation="MLVYYLYNLIFLEGGVITLKLKIVGSGGMSIIPSSFCKCKICEE
                     ARQKGGRYERLGPSLYIDDIKMLIDTPEDIAVACNRQKISEVKHISISHHDPDHVKGI
                     RIVEKIGCDFITGENNPIGFYALPEVIEDINRTNLDCLKYYGDVINCISINETSHVKI
                     NNFDIDLINNNPDRNITFYVIKENEKKVIYACCNPKPFTHSDMYFDADILIISLVSDD
                     GILNDGTKLKDTPFKDEIFTLDEIVEIKNYYRIKKIIVTHIDEMWGKSYGYYSELEKK
                     LDNIYFAYDGMEIIV"
     gene            complement(1900..2679)
                     /locus_tag="ACGI5H_003879"
     CDS             complement(1900..2679)
                     /locus_tag="ACGI5H_003879"
                     /EC_number="1.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436810.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family NAD(P)-dependent oxidoreductase"
                     /protein_id="HFG9699550.1"
                     /translation="MSYKKIAIITGANSGFGKEFLKLLINEEEITEIWAVARNKARLN
                     QLVDEFGSKVKIFSKDLSKIEEVKEIGTFLSKENVCIKYLINNAGFAKFCSYNDLSID
                     ESINMIDLNISAVVALGLICIPYMQKGSHIMNISSQASFQPLPYQNIYSSTKAFIRNY
                     TRALNVELKSKGINAIAVCPGWMSTNLFKRGIVVAEKGTKNFPGIVSPDVVAKKALKD
                     AKKNKDISVYGINTKSSHLLAKLLPQKMMMKVWLMQQHIKE"
BASE COUNT         1151 a          399 c          375 g         1193 t
ORIGIN      
        1 atcacttgtg atgttatgtt taaatgacta gaatttgatt gggatattat cttaatttgt
       61 cagataaatc aattgtgatg ttgtgtttaa atgactagaa tttgattagg atattatctt
      121 aatttgtcag ataaattatt tataatgtta tgtttaaata cctacaattt aattaggata
      181 ttatctcaat ttgtcagata aatcaattat gattttatgt ttaaatgact agaatttgat
      241 taggatatta tcttaatttg tcagataaat caattataag attatatact atccttatac
      301 tctagttaaa tatattttaa tcactaatat aaattagttt ttttaacaaa acaataaaag
      361 agtaaagtac aaataattcc tttgtactct actcttttta actttctttg tacaataata
      421 caatgataaa tataaaaaat tatatattcc attctataga aatatgctca ccaataacat
      481 gtatgttgtt aatcaatata ttatatcaaa ttatatcaaa attacataaa ccttatagga
      541 caatcatatc ttattacaag aaaaatgtct tatccatatt gaataagtca ttcagttcat
      601 atacaaagtc aatttcattg agaaacattt aatatatgtt tataaaaatt tcatactatt
      661 ctttcatatt tacatgtgat ataatttatt aactcataat tttgttaatc agttgtgctt
      721 gtatattatt tatataatct aatattttta gaaggtggtg taataacttt gaaattaaaa
      781 attgttggta gtggcggtat gtcaattatt ccaagttcat tttgtaaatg caaaatatgt
      841 gaagaagcca ggcaaaaagg cggaagatat gaacgattag gaccaagttt atatattgat
      901 gatataaaaa tgctgataga cacacctgaa gacattgcag tagcttgtaa cagacaaaaa
      961 atatcggaag taaaacatat ttcaatttct caccatgacc cagaccatgt taagggtatt
     1021 agaattgtcg aaaaaatagg atgtgacttt atcacaggag aaaataatcc aattggcttt
     1081 tatgcgcttc ctgaagtaat tgaagatata aaccgaacga atctcgattg tcttaaatat
     1141 tatggtgatg ttataaattg catttctatt aatgaaactt cgcatgtaaa gataaataat
     1201 tttgatattg atttgattaa caataaccca gacaggaata taaccttcta tgttatcaaa
     1261 gagaatgaaa aaaaagtcat atatgcctgc tgtaatccca agccatttac tcatagtgat
     1321 atgtactttg atgctgatat tttaataata agtctagttt ctgatgatgg tatattaaat
     1381 gatggtacaa aacttaaaga cacaccattt aaagatgaaa tatttacttt agatgagatt
     1441 gttgaaatta aaaactatta tagaattaaa aaaattattg ttacacatat tgacgaaatg
     1501 tggggaaaat catatggtta ttacagtgaa ttagaaaaga aacttgataa catttatttt
     1561 gcatatgatg gtatggaaat tatagtctaa atcattaagt aataagcata atgcaaaata
     1621 agaaaacttc aatttaacag tatagtcaaa ctatgtgata tcaacatatc gcagttttta
     1681 caaaatatca tagtatttat ctttataaaa tttcaagtcc tacatatttt aatacttcaa
     1741 tatctaaata aagtaaaatc aaaaatatat tttatataca ttatagacgg cttatcgtca
     1801 ctagataagc cgttttgtca caattattat ttgctcaaca aaacttctca taatatataa
     1861 cagattgaat ctccaactga tacttaatta ccaaaactct tattccttaa tatgttgttg
     1921 cattaaccaa accttcatca tcattttttg tggcaatagt tttgctaata aatgactgga
     1981 ttttgtattt ataccataca cagaaatatc cttatttttc tttgcatcct tcaatgcttt
     2041 tttggcaaca acgtctggag acactatgcc tgggaaattt tttgtccctt tttcagctac
     2101 aactatacct ctcttaaata gatttgtact catccaacct ggacatacag caattgcatt
     2161 tatcccttta ctcttaagtt caacatttaa tgctcttgta taatttctta taaacgcttt
     2221 agttgaacta taaatatttt gatatggcaa tggctggaat gatgcttgtg aagaaatatt
     2281 catgatatgg cttccctttt gcatatatgg aatacatata agtcccaatg ctacaacagc
     2341 actaatattt aaatcaatca tattaataga ttcatctata cttaaatcat tgtatgaaca
     2401 gaattttgca aaaccagcat tgtttataag gtattttata catacatttt ctttacttaa
     2461 aaatgtacca atttctttta cttcttctat ttttgataaa tcttttgaaa aaatttttac
     2521 cttacttcca aattcatcta ctaattgatt taatctcgcc ttgtttcttg caactgccca
     2581 tatttctgtt atttcttctt catttattaa taactttaga aactctttac caaaaccact
     2641 attagcaccc gttataattg caatcttctt ataactcata attattctcc tttaccataa
     2701 gtttatacgc tcaaactgta aacttatttt ttacaaataa aacaccctct attcagatgt
     2761 tatattcata ttatttgaga tattatattt atatcatttt caataattgt tatatagcat
     2821 aaaaaatagt gttaatatta tagaatcggt attgattata tttaaaaagt agtgttaatt
     2881 atattataga atcagtattt attatattat aaaaagtagt gttaatatta tagaatcgat
     2941 attgattata tttaaaaagt agtgttaatt atattgtaga atcagtattg attatattgt
     3001 aaaaagtagt attaataata ttgtagaatc aatattgatt atatttaaaa aagtagtgtt
     3061 aattatattg tagaatcagt attgattata ttataaaaag tagtattaat aatattgt
//
LOCUS       DAYAOO010000181         3116 bp    DNA     linear   BCT 12-OCT-2024
DEFINITION  TPA_asm: Clostridioides difficile isolate ST8-SSI-h139-18
            SAMN40601845-rid21577343.denovo.185, whole genome shotgun sequence.
ACCESSION   DAYAOO010000181 DAYAOO010000000
VERSION     DAYAOO010000181.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN40601845
            Sequence Read Archive: SRR28438827
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 3116)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3116)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-MAY-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-MAY-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002157583.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002157583.1
            Genome Coverage       :: 163x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/11/2024 16:19:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 4,038
            CDSs (total)                      :: 3,963
            Genes (coding)                    :: 3,930
            CDSs (with protein)               :: 3,930
            Genes (RNA)                       :: 75
            rRNAs                             :: 6, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 60
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 33
            CDSs (without protein)            :: 33
            Pseudo Genes (ambiguous residues) :: 0 of 33
            Pseudo Genes (frameshifted)       :: 7 of 33
            Pseudo Genes (incomplete)         :: 25 of 33
            Pseudo Genes (internal stop)      :: 11 of 33
            Pseudo Genes (multiple problems)  :: 8 of 33
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3116
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN40601845-rid21577343.denovo.185"
                     /isolate="ST8-SSI-h139-18"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Denmark"
                     /collection_date="2018"
                     /collected_by="Statens Serum Institute"
     gene            complement(157..423)
                     /locus_tag="ACGI5H_003880"
     CDS             complement(157..423)
                     /locus_tag="ACGI5H_003880"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889660.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3795 domain-containing protein"
                     /protein_id="HFG9699551.1"
                     /translation="MIESRCGILCYECGYKEKVNCKGCTEIEKPFWGEQCPVKSCCED
                     KNLTHCGLCDTFPCEMLNQFAYDKEQGDDGKRISQCKKWAVLAL"
     gene            complement(465..1274)
                     /locus_tag="ACGI5H_003881"
     CDS             complement(465..1274)
                     /locus_tag="ACGI5H_003881"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896869.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_function: GO:0043565 - sequence-specific DNA binding
                     [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HFG9699552.1"
                     /translation="MNKIINNILNTCKQYTYILPHKLLRQYIAHYTISIPDTSIKENL
                     TLIPDASGCMIFKFDKKGIESAFWGATTKTTIVKNDIENVLFRVFVEFRPGGVYYLTG
                     LSQRESTDLKISLEDFNTLFSLEVNSIFERTSTIKELVEQLDMLFLSYLLKSNIVDMT
                     IPILENARKQNSIMSVKNISQISCYSERHLNRIFNNSLGMSVKSYLRLLRINLVLQEI
                     QNNKIPFATLAQDIGYYDQSHFINDFKSICGVNPTTYIKNLSDFYNEKYKF"
     gene            1587..1868
                     /locus_tag="ACGI5H_003882"
     CDS             1587..1868
                     /locus_tag="ACGI5H_003882"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420428.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9699553.1"
                     /translation="MASKQIPRNNLEKFLRIRVLSHTGDKIHIKLPVNFAKRMIENNA
                     LDLFNGKDDVVDGKKVTEILVKAFDYDLTGEVVHLERKNGDIIKVSIVQ"
     gene            2132..2386
                     /locus_tag="ACGI5H_003883"
     CDS             2132..2386
                     /locus_tag="ACGI5H_003883"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905281.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9699554.1"
                     /translation="MENKDFKLTICIFAFVIGVVVLFCCIGLGEFSAEHIIQQNGGIM
                     DTDQYNIYLDQSISQYRNFGSILALLGGIGILFDKYIRKY"
     gene            2431..2754
                     /locus_tag="ACGI5H_003884"
     CDS             2431..2754
                     /locus_tag="ACGI5H_003884"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889674.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF6054 family protein"
                     /protein_id="HFG9699555.1"
                     /translation="MATEIFTVKITPLEAQKMIKENLDADLVFSDSYNLGDDKFILIT
                     TFEKYYARNNSDAGLIVVYENTTGKTVIKATSTGSAIGILKIDWGAGGNLLKRVKNIL
                     ADYII"
BASE COUNT         1232 a          313 c          416 g         1155 t
ORIGIN      
        1 tttccaattt tagtaatcag attttatcaa taaattacta ttctattaat ttaattaaat
       61 aacctttaaa tttaattata aaaactgttg cagaaatttc tacaacagtt taaaaaattt
      121 accttacaaa aacttatttt ataacaagag agtatattat aaggctagta cagcccattt
      181 tttgcactga gaaattcttt tgccatcatc accttgttct ttgtcatatg caaattgatt
      241 aagcatttca catggaaatg tatcacatag accacaatgt gtaaggtttt tatcttcaca
      301 acaagatttt acaggacatt gttcacccca aaatggtttc tcaatctctg tacaaccttt
      361 acaattgact ttttccttgt atccacattc ataacataaa attccacatc ttgattctat
      421 cattttaagt cactccttaa atataaattt tatatgattg tatatcaaaa tttatacttt
      481 tcattgtaaa aatcggacaa attttttata taggttgttg gattaacacc acaaatagat
      541 ttaaaatcat ttataaaatg agattggtcg taataaccaa tatcttgtgc taaagttgca
      601 aatggtattt tattattttg tatttcttgt aatacaaggt ttatacgaag taatctaagg
      661 tatgatttaa cactcatacc aagagaatta ttaaaaattc tatttaaatg tcgttcacta
      721 taacaactaa tttgtgaaat gtttttaaca gacataatag agttttgttt tctagcattt
      781 tcaagaattg gtatagtcat atctactata tttgatttca ataagtatga taagaataac
      841 atatctaatt gttctactaa ttcctttata gtacttgttc tttcaaaaat ggaattaacc
      901 tctaagctaa ataatgtgtt aaaatcttca agtgaaattt ttaaatctgt agattctctt
      961 tgagaaagac ctgtcaaata atatactcca cctgggcgaa actcaacgaa tactctaaaa
     1021 agtacatttt ctatatcatt ttttacaata gtagtttttg ttgtggctcc ccagaatgcg
     1081 ctttctatac cttttttgtc aaatttaaat atcatacatc cactagcatc aggtattaat
     1141 gtaagatttt ctttaatact tgtatctgga atagatattg tatagtgtgc tatatactgt
     1201 cttaacaatt tatgtggcaa aatatatgta tactgtttgc aggtatttaa aatgttattg
     1261 attattttat tcataagtat atcctcctga tatataaaaa ataagtatac taatttattt
     1321 tttatataat aaaccagttt tgttttaatt gaaatattct aataagatat tttgttaaat
     1381 ttagatacaa taattgtaaa gtaaaatctc aaaatataca attattataa atcatagata
     1441 tttattaaat aaatatatta aagaagaagg aatataaaac aagattagaa aataatagtg
     1501 ttactttcat aataaataca tataaagata tttttaagaa taaaatttat tattaaataa
     1561 aaaataaagg agagtgattt aatagcatgg catcaaaaca aataccaaga aacaatttag
     1621 aaaagttttt aagaataaga gtcttatcac atacaggcga taaaatacat ataaagttac
     1681 ctgtaaattt tgcaaagaga atgattgaga ataatgcttt ggatttattt aatggaaaag
     1741 atgatgtagt agatggtaaa aaagttactg aaatattagt taaggcattt gactatgatt
     1801 taactggaga agtagttcac ttggagagaa aaaatggaga cattattaaa gtttcaattg
     1861 tacaatagaa ttattttata tgaattttat ttttgaatag ttataaataa ttagaaattt
     1921 gtaaaaaagt ataatatatt attagtaatg gtacagaata cacatttata atttatagat
     1981 gtgtattttt tgtttaaaaa atttaaatat ataaaactat aaaggttaca attttggaaa
     2041 tagatgtaaa tatatgttgt attgtataat aagagtaata taaaatctag taaaaataat
     2101 caaataaatt tagcttatga gagggataac tatggaaaat aaggatttta aattaacaat
     2161 atgtatattt gcttttgtaa ttggagtagt agtattattc tgttgtatag gtttaggtga
     2221 atttagtgca gagcatatta ttcaacaaaa tggtggaatc atggatactg accaatataa
     2281 tatttatcta gaccaatcta tttctcaata tagaaatttt ggttctatat tagctctgtt
     2341 aggaggaata gggatattgt ttgataaata tatcagaaaa tactagagat tatgttttgt
     2401 ctaaaataaa ttcttatgag gagataaaaa atggcaacag aaatatttac tgtaaaaatt
     2461 acacccttag aggcacaaaa aatgataaaa gaaaatcttg atgcagattt agtttttagt
     2521 gattcttata atttaggaga tgataaattt atactaatta caacttttga gaagtattat
     2581 gcaagaaata atagtgatgc aggattaata gtagtttatg aaaataccac aggaaaaaca
     2641 gttattaaag ctacttcaac aggcagtgca attggaattt taaaaattga ttggggtgca
     2701 ggtggaaatt tacttaaaag agtaaaaaac atacttgctg attatattat ttaattattt
     2761 tatctaactg ataatatgtc aagaaaatct cgtaaaagag gttaagaaca tttttataat
     2821 atatagataa ataagaattt gaaggtaaag tttttaaggt ataaagaaaa ataatataat
     2881 aaaacgaatt ggctttataa ttctttataa ggcaaagagc acatttcttt atataattgt
     2941 tggatattaa ataatatgta aatacaccat ttacatataa aagtttaatt aatatgttaa
     3001 gagaaaatga aatggaaatt actaaaaaat atttttaaat tggataatgg ttgatattat
     3061 gtttatacaa aaatcatgta gaattttata tattttaaat atgatagttt aaaatt
//
LOCUS       DAYAOO010000182         3078 bp    DNA     linear   BCT 12-OCT-2024
DEFINITION  TPA_asm: Clostridioides difficile isolate ST8-SSI-h139-18
            SAMN40601845-rid21577343.denovo.186, whole genome shotgun sequence.
ACCESSION   DAYAOO010000182 DAYAOO010000000
VERSION     DAYAOO010000182.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN40601845
            Sequence Read Archive: SRR28438827
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 3078)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3078)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-MAY-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-MAY-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002157583.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002157583.1
            Genome Coverage       :: 163x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/11/2024 16:19:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 4,038
            CDSs (total)                      :: 3,963
            Genes (coding)                    :: 3,930
            CDSs (with protein)               :: 3,930
            Genes (RNA)                       :: 75
            rRNAs                             :: 6, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 60
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 33
            CDSs (without protein)            :: 33
            Pseudo Genes (ambiguous residues) :: 0 of 33
            Pseudo Genes (frameshifted)       :: 7 of 33
            Pseudo Genes (incomplete)         :: 25 of 33
            Pseudo Genes (internal stop)      :: 11 of 33
            Pseudo Genes (multiple problems)  :: 8 of 33
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3078
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN40601845-rid21577343.denovo.186"
                     /isolate="ST8-SSI-h139-18"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Denmark"
                     /collection_date="2018"
                     /collected_by="Statens Serum Institute"
     regulatory      <1..64
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF01051"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="cyclic di-GMP riboswitch class I; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /bound_moiety="cyclic di-GMP"
                     /db_xref="RFAM:RF01051"
     gene            147..632
                     /locus_tag="ACGI5H_003885"
     CDS             147..632
                     /locus_tag="ACGI5H_003885"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889961.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SH3 domain-containing protein"
                     /protein_id="HFG9699556.1"
                     /translation="MISELMLKNFRKSSINFKTKIKLNLREKPDINSLKLKSIPEGKI
                     VKLKCVDGIWAEVESNYDKGWLLYKYLERLSNAKNNSNDTIKNRKKNYIGNIRTNGLS
                     LELRNDRTLESKVITTIPDGFKVEVCYSVGKWARVNINKNEKRYSGYVYNQYIEEHLS
                     L"
     gene            988..1386
                     /locus_tag="ACGI5H_003886"
     CDS             988..1386
                     /locus_tag="ACGI5H_003886"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861413.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9699557.1"
                     /translation="MNKKKKLIGIAISFLLIISIINPLQVEAEAIIESSVYISSIKEN
                     YTYDNTKFKTIKSKSRHKSRKYNKSKVKLKKRSIRTKKYGYQTINKYKRQNARRHNIL
                     TKLILSIIVIFLVIVLVVLIFIKRKKKKFY"
     misc_binding    1822..2085
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            2236..2787
                     /locus_tag="ACGI5H_003887"
     CDS             2236..2787
                     /locus_tag="ACGI5H_003887"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424155.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tryptophan transporter"
                     /protein_id="HFG9699558.1"
                     /translation="MKTNTKKLTLNAILLAMGLLIHQITPAIGLPMKPDVPLAMLFVI
                     LVLNRDDYKTCLIAGIVTGIFTALTSSFPGGQIPNVIDKTLTANIVFLLMNISYNMPF
                     IKKLAKKTQDTVVVAIIMPIGTLVSGTIFLLAAQAIVGLPGASFTALFLAVVLPAVLI
                     NLVAGIFLFKIVSLSIRRVSYQA"
BASE COUNT         1315 a          280 c          443 g         1040 t
ORIGIN      
        1 atgacgcaaa actataggga ctaaaatctt tatgtaataa aggtcatgtc agccagttgc
       61 caaaaagata ataattcttt ttgttaaaag tatttttaga gttatatatt ttaataactt
      121 aatatttggc aagaggaggg cttaagatga tatctgaatt aatgttaaaa aattttcgca
      181 aatctagcat caattttaag actaaaatta aattgaattt aagagaaaaa ccagacataa
      241 atagtttgaa attaaaaagt ataccagaag gtaaaattgt taagttaaag tgtgtagatg
      301 gaatatgggc agaagttgag agtaattatg acaaaggttg gttactttat aaatatttag
      361 aaagattaag taatgctaaa aacaatagta atgatacaat aaaaaataga aaaaagaatt
      421 acataggaaa tataagaaca aatggattaa gtttagaact tagaaatgat agaacattag
      481 aatctaaagt tataactaca atccctgatg gttttaaagt tgaagtatgt tatagcgttg
      541 gaaaatgggc aagagttaat atcaataaaa atgaaaaacg atattctgga tatgtatata
      601 atcaatacat agaagagcat ttaagtttat aatacgatac tagcaagctt taaatatatt
      661 aataaatcgc aaaaaagaat cccattaatg ggattctttt ttgtagaaac attataacag
      721 aactaaagag aataaattaa ctaatttatt tttattataa agtaattata aatggtaaat
      781 ttaattgaaa gtagatttaa cttatacttt atacaccaag tatcataaat taatactact
      841 ttgaaaaatc ttaaaaaaag taaaagttat gataataaaa ataatattaa agataataag
      901 atatataaga aacttgaaaa aatttgtaat ttttagttat atatatatta taatgaacta
      961 gttaaaaatt tttatgaggg ggaaaatatg aataagaaga aaaaattgat tgggatagct
     1021 atatcttttc tacttataat cagcattata aatccattac aagtagaagc agaagctatt
     1081 attgagtcta gtgtatacat ttcttcaata aaagagaatt atacatatga taatactaaa
     1141 tttaaaacta ttaaatctaa aagtagacat aaaagtagga aatataataa aagtaaagta
     1201 aagttgaaaa aacgaagtat aagaactaaa aagtatggat atcaaactat aaataaatat
     1261 aaaagacaaa acgcaagaag acataatatc ctaacaaaat taatattgtc cataatagtc
     1321 atatttttgg ttatagtttt agtagtgcta atatttatta aaagaaagaa gaaaaaattt
     1381 tactaaaaat aattaaaaga atatcatttt tttaatcatt ggtatctatt taataatatg
     1441 atgtaattaa aatggagtaa tattctgttt caaaggaggc atataaatac aggaatgagt
     1501 attaaatgat ggttaattaa gtaaatttat tgataaatgt acttaattaa ctttgaagaa
     1561 tttaattcct catgaatcaa aatataaaat tacatcaaca gttattcaca aaattaatat
     1621 aagaagaatt agagccaaag agcagactat tagaccatta aagtaattat tcatagaatt
     1681 ttgtatatga aaagaaatgt atagtataat ttactttttt tataaaaaat agattacaaa
     1741 atatattttt tataaaaagg tattgacatt ttttagaaaa aagaatatca ttattttaac
     1801 aacaaaattc aatacaataa attaaatcct atgacaagga agagtagtta aatttaggtt
     1861 cagtatagag agctgaggat ggtggaatct tagcaagaaa aaatttgatg aatggccctt
     1921 agaggaataa attgaaatca tagttttgag agtagacttt atcgtcagtc gcacgttata
     1981 gcgaataagg tatgtaagta cctgataatg agatgtatga aaattgaatt ttatattaat
     2041 ttttatataa tttaggtggc aacgcggata atctccgtcc tattagttta ggacggagtt
     2101 ttttatttta ctgaaaattt aaaagataga aggtggtgag aaagatgtta tgaatttcaa
     2161 aagctaaaga tgatgatata gtaggttggc aaaaaaataa attgaaaatt aaaaaaatag
     2221 gaggaagtac aaaaaatgaa aacaaataca aaaaaattaa ctttaaatgc aatactttta
     2281 gcgatgggat tattaataca tcaaatcaca ccagctatag gattaccaat gaagccagat
     2341 gtaccactag caatgttatt tgtaatattg gttttaaata gagatgatta taaaacttgt
     2401 ttgatagcgg gtatagtaac aggaatattt acagcactta catcaagttt tccgggaggt
     2461 caaattccta atgtaataga taaaactctt acagcaaata tagtattttt attaatgaat
     2521 attagttata atatgccttt tataaaaaaa ttagctaaga aaacacaaga tactgtagta
     2581 gttgcaataa taatgccaat aggaactctt gtaagtggaa ctatcttttt attagcagct
     2641 caagctatag ttggtcttcc aggggcttca tttacagctt tattcttagc agtagtatta
     2701 ccagctgttt taataaatct agttgcagga atatttttat tcaagattgt tagtctatca
     2761 ataagaagag ttagttatca agcttaaaca cgaaataata ttttacttta taaagcatta
     2821 taataactaa ataacataag aataaagtag attataacta ttttattctt atgttgttta
     2881 aagatttggt attatatatt tatttttaat aaaatattta tatagtacca attacactta
     2941 atttaacaga taaattatca tacctatata atattcttat atgtatctca tttgtagtta
     3001 ttaaatataa gatatattta attgactttt caagataaat ttttatatta atctcctctg
     3061 atttctcatt ttttgaat
//
LOCUS       DAYAOO010000183         3069 bp    DNA     linear   BCT 12-OCT-2024
DEFINITION  TPA_asm: Clostridioides difficile isolate ST8-SSI-h139-18
            SAMN40601845-rid21577343.denovo.187, whole genome shotgun sequence.
ACCESSION   DAYAOO010000183 DAYAOO010000000
VERSION     DAYAOO010000183.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN40601845
            Sequence Read Archive: SRR28438827
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 3069)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3069)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-MAY-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-MAY-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002157583.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002157583.1
            Genome Coverage       :: 163x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/11/2024 16:19:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 4,038
            CDSs (total)                      :: 3,963
            Genes (coding)                    :: 3,930
            CDSs (with protein)               :: 3,930
            Genes (RNA)                       :: 75
            rRNAs                             :: 6, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 60
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 33
            CDSs (without protein)            :: 33
            Pseudo Genes (ambiguous residues) :: 0 of 33
            Pseudo Genes (frameshifted)       :: 7 of 33
            Pseudo Genes (incomplete)         :: 25 of 33
            Pseudo Genes (internal stop)      :: 11 of 33
            Pseudo Genes (multiple problems)  :: 8 of 33
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3069
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN40601845-rid21577343.denovo.187"
                     /isolate="ST8-SSI-h139-18"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Denmark"
                     /collection_date="2018"
                     /collected_by="Statens Serum Institute"
     gene            <1..1095
                     /locus_tag="ACGI5H_003888"
     CDS             <1..1095
                     /locus_tag="ACGI5H_003888"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422637.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AMP-binding protein"
                     /protein_id="HFG9699559.1"
                     /translation="ISDESMDVIDLYDDNNNEVAKKVNFSIFNPKFNIYMYQYKKLIN
                     YLDKSICMGALSSGSTSVPKVLYRTYESWAGFFPIQNGIFNISGESILFVNGTLSFTG
                     NLNSIMSVLYEGGSIVISSGLNCKSWIRTIKQYNVTNIYLIPTKLQLLVKHLKEPVLK
                     VVSIFTGSQLLFEDTARNLKKYMPKSEIILYYGASELNYITYLCYDELIEKPLSVGRP
                     FPGIDIYIREGKIFVNTEYAVYNATKPYSVNDIGYYDNDGYLIFEGRSDDIINIGGFK
                     VSSTKIENEVKKIPQIEDAIVLPYSDTIRGNQIVLFVITIDKITKKDLLIKMKDNLMK
                     NEIPKKIIFLNSFPYTSSEKIDRLALLKML"
     gene            1171..2046
                     /gene="dpsA"
                     /locus_tag="ACGI5H_003889"
     CDS             1171..2046
                     /gene="dpsA"
                     /locus_tag="ACGI5H_003889"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898070.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dipicolinate synthase subunit DpsA"
                     /protein_id="HFG9699560.1"
                     /translation="MSNQYDITVIGGDLRQVYMVKKLINKGYSVVTYGISNEIINGIV
                     GKSTSLAEALSKSSIILCPIPFTKNQVNIENTDDCLDATIDNLLINLSPNQILFGGNI
                     PTKVCKFCEQHSIQIYDFMKMNDVAILNAVATAEGAIAEAIKRSIINIHQSNCLVLGY
                     GRCAQILAKKLYALDANVCVGARNNDARSTANAFGYSSISLSQLDEKLLQFDYIFNTI
                     PECILTKERLEKVSQEVTIIDIASSPGGVDYSVVKEAGINATLCLGLPGKYSPKTSGE
                     ILVNAIENIINERRD"
     gene            2049..2639
                     /locus_tag="ACGI5H_003890"
     CDS             2049..2639
                     /locus_tag="ACGI5H_003890"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429956.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003824 - catalytic activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="dipicolinate synthase subunit B"
                     /protein_id="HFG9699561.1"
                     /translation="MRLEGLTIGVGFTGSFCTYDKIFIELENLVKEGANVHTIFSDVS
                     QNIDCRFGNSEEFMKKAYELTGNKPIVTIEEAEPFGPKGIADIIIIAPCTGNTAAKLA
                     NGITDSPVLMAAKGHLRNDKPLVISISTNDALSFNFKNIGILLNSKNIYFVPFGQDNC
                     KAKPNSMIAHTELIIPTIELALENKQLQPVIKSPHQ"
     gene            complement(2846..>3069)
                     /locus_tag="ACGI5H_003891"
     CDS             complement(2846..>3069)
                     /locus_tag="ACGI5H_003891"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=3
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9699562.1"
                     /translation="FIRRRISMEKLKTISVFSLIISVILTIGGIGIVTYYVDNLFIRG
                     LSVFVLIMSSSFVSTTVRLIFEESKRYKF"
BASE COUNT         1172 a          388 c          481 g         1028 t
ORIGIN      
        1 atatctgatg aatctatgga cgttattgat ttatatgatg ataacaataa tgaagtagca
       61 aaaaaagtta atttttctat ttttaatcct aaatttaata tatatatgta tcaatataag
      121 aagcttataa attatttaga taaaagtatt tgtatgggag ctttatcttc aggttctaca
      181 agtgttccaa aggtattata tagaacatat gagagttggg ctggattttt tcctatacaa
      241 aatggtattt ttaatatctc tggggaatca atcttgtttg ttaatggaac acttagtttt
      301 acagggaatc taaattctat aatgtcagta ttatatgaag gaggtagtat tgtaataagt
      361 tcaggtctta attgtaaatc atggataagg acaataaaac aatataatgt aactaacata
      421 taccttatac ctacaaaact tcaacttttg gttaaacact taaaagaacc agtactcaaa
      481 gttgtaagta tttttacagg gtctcaatta ttatttgaag atactgcaag aaatctaaaa
      541 aaatatatgc caaagtctga aattatttta tactatgggg caagtgaatt aaattatatt
      601 acatatttat gctatgatga actaattgaa aaacctctaa gtgtaggcag accatttcca
      661 ggaatagata tatatattag agaaggaaaa atttttgtga atacagaata tgcagtatat
      721 aatgcaacca aaccttattc tgtcaatgat attggatatt atgataatga tggatactta
      781 atatttgaag gaagaagtga tgacattata aatattggag gatttaaagt tagttctact
      841 aagattgaaa atgaagttaa aaaaattcct caaattgaag atgcaattgt attgccgtac
      901 tcagacacta taagaggaaa tcaaattgta ttatttgtaa taactataga caaaattacg
      961 aagaaagatt tgttgattaa aatgaaagat aatctaatga aaaatgaaat cccaaagaaa
     1021 attatctttt taaattcatt tccatatacc tcttctgaaa agatagatag attagcatta
     1081 ttaaaaatgt tataagtata atatttagta attttagtga accaatgtat tgataaaaac
     1141 atattgtata tagtaaagga ggcttacaat atgtcaaatc aatacgatat aactgttatt
     1201 gggggagacc tgcgacaagt gtacatggta aaaaaactaa ttaataaagg gtattctgta
     1261 gtcacttatg ggatatcaaa tgaaattata aatggaatcg ttggaaaatc aacttcacta
     1321 gctgaagcac tatccaaaag ttccattatt ttatgtccaa ttccatttac aaagaatcaa
     1381 gttaatattg aaaatacgga tgattgtctt gatgctacta ttgataactt gctaattaat
     1441 ttatctccta atcaaatatt atttggaggt aacataccaa ctaaagtttg taaattttgc
     1501 gagcaacact ctattcagat ttatgatttt atgaaaatga atgatgttgc tattttaaat
     1561 gcagttgcta cagctgaagg ggctatagca gaagctatta aaagaagtat aatcaatata
     1621 catcaaagta actgtttagt attaggttat ggaagatgtg cacaaatact tgcaaaaaaa
     1681 ttatacgctt tggatgcaaa tgtatgtgtt ggcgcaagaa ataatgatgc aagaagtacg
     1741 gctaatgcat ttggatattc cagtatttct ttaagtcaac ttgatgaaaa acttttacaa
     1801 tttgattata tttttaacac cataccagag tgtattttaa cgaaagaaag gttagaaaaa
     1861 gtatcacaag aagtaactat tatagatata gcttcttctc ctggaggagt agattattct
     1921 gttgttaaag aagcagggat taatgcgact ctttgccttg ggcttcctgg taaatattca
     1981 ccaaagacat ctggtgaaat tcttgttaac gctatagaaa atattataaa tgaaagaagg
     2041 gattagaaat gagacttgaa ggacttacaa ttggagtagg atttactggt tcgttttgta
     2101 cttatgataa aatatttata gagttagaga atttggttaa agaaggagct aatgtacaca
     2161 ctatattttc agatgtatca caaaatatcg attgtagatt tggaaattct gaagagttta
     2221 tgaaaaaagc atatgaactt acaggaaata aacctatagt tacgattgaa gaggcagagc
     2281 catttggacc taaaggaatt gctgatatta taataatagc tccttgtact ggaaatactg
     2341 ctgcaaaatt agcaaatggt attacagatt caccagtatt aatggcagca aaaggtcatc
     2401 ttcgtaatga taaaccacta gtaatatcaa tatcaacgaa tgatgctcta agctttaatt
     2461 tcaaaaatat tggcattctc cttaattcta aaaatatata ttttgtacct tttggtcaag
     2521 ataattgcaa agcaaagcct aattctatga ttgcacatac tgagctaata attccaacta
     2581 tagaacttgc tctagagaac aaacagctac agcctgttat aaaaagtcca catcaataga
     2641 attggttctt ataatattat gtattagata caatactagc aaagaggctg tctcaaaata
     2701 gagagaagcc tctttttctt gttgaaatga tgaaaatata tttaatttca tacaaaaaaa
     2761 tgcctcatgg actaaaaagt ctattttgag ctaatctccg taatttttgc tatattaaaa
     2821 ttatttactt aatccaattt ttaaattaga atttatatcg ttttgactct tcaaatatca
     2881 atctaactgt tgttgataca aaagaagagg acataattaa aacaaatact gatagtcctc
     2941 taataaacaa attatctaca taataagtta ctattccaat acctccaatc gttaaaatta
     3001 cacttataat caaagaaaaa acgctaattg tttttaattt ttccatgctt atcctccttc
     3061 ttataaact
//
LOCUS       DAYAOO010000184         3036 bp    DNA     linear   BCT 12-OCT-2024
DEFINITION  TPA_asm: Clostridioides difficile isolate ST8-SSI-h139-18
            SAMN40601845-rid21577343.denovo.188, whole genome shotgun sequence.
ACCESSION   DAYAOO010000184 DAYAOO010000000
VERSION     DAYAOO010000184.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN40601845
            Sequence Read Archive: SRR28438827
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 3036)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3036)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-MAY-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-MAY-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002157583.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002157583.1
            Genome Coverage       :: 163x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/11/2024 16:19:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 4,038
            CDSs (total)                      :: 3,963
            Genes (coding)                    :: 3,930
            CDSs (with protein)               :: 3,930
            Genes (RNA)                       :: 75
            rRNAs                             :: 6, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 60
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 33
            CDSs (without protein)            :: 33
            Pseudo Genes (ambiguous residues) :: 0 of 33
            Pseudo Genes (frameshifted)       :: 7 of 33
            Pseudo Genes (incomplete)         :: 25 of 33
            Pseudo Genes (internal stop)      :: 11 of 33
            Pseudo Genes (multiple problems)  :: 8 of 33
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3036
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN40601845-rid21577343.denovo.188"
                     /isolate="ST8-SSI-h139-18"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Denmark"
                     /collection_date="2018"
                     /collected_by="Statens Serum Institute"
     gene            307..1239
                     /locus_tag="ACGI5H_003892"
     CDS             307..1239
                     /locus_tag="ACGI5H_003892"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006441199.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Rossmann-like and DUF2520 domain-containing
                     protein"
                     /protein_id="HFG9699563.1"
                     /translation="MGFIGSGKVGTSLANYFLSKGYCVSGFYGRNQLSLLESTNLTKT
                     KIYSNLKDIIYENDILFITTSDDSIEIIDKKLSKFNLKHKYICHTSGSLKSSILFCSK
                     KAGALIYSIHPIFAFSNKNTDIKKMKDICFSIEGDNEQDDLVIQNFIDDLGNQFFIRD
                     KDTSSTYHLANVLVSNLVLSLLDIGVSYFIKLGLSEEESLKAISPLVKKNIENILDNG
                     FTKALTGPVSRGDITPIRKHLSVLDKKDEDIYKILSLNLLKIIALGNDNSLKGIKNIT
                     IENAIENLISKSEKYKEIYKLLGGKNDEKYHTDF"
     gene            1214..2041
                     /gene="panB"
                     /locus_tag="ACGI5H_003893"
     CDS             1214..2041
                     /gene="panB"
                     /locus_tag="ACGI5H_003893"
                     /EC_number="2.1.2.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439367.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003864 - 3-methyl-2-oxobutanoate
                     hydroxymethyltransferase activity [Evidence IEA];
                     GO_process: GO:0015940 - pantothenate biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="3-methyl-2-oxobutanoate
                     hydroxymethyltransferase"
                     /protein_id="HFG9699564.1"
                     /translation="MKNTIQTFKNAKYEGKKLSMLTAYDYSIAKIMDECDINGILIGD
                     SLGMVIKGEENTLSVTIDEIIYHTKAVKNGVKNALIVSDMPFLSYHVSIEDAVKNAGR
                     LIKEGGAHAVKLEGGSNVIKQIESIVNAQIPVMGHLGLTPQSVNSFGGFKVQGNTSET
                     ARQLIEDAKLIEKAGAFSIVLEGVPTKIAEMVTNSISIPTIGIGAGINCDGQILVYQD
                     MLGMFGDFVPKFVKQYANIGDIIKDSIKNYILEVNTGAFPQEKHSFSINESELEKLY"
     gene            2060..2908
                     /gene="panC"
                     /locus_tag="ACGI5H_003894"
     CDS             2060..2908
                     /gene="panC"
                     /locus_tag="ACGI5H_003894"
                     /EC_number="6.3.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439366.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004592 - pantoate-beta-alanine ligase
                     activity [Evidence IEA];
                     GO_process: GO:0015940 - pantothenate biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pantoate--beta-alanine ligase"
                     /protein_id="HFG9699565.1"
                     /translation="MLVKEIKLLRNIIKDWRKHGYSIGLVTTMGFLHEGHQSLIKKAV
                     KENDKVVVSIFVNPTQFGPNEDFNSYPRDIDKDFKYCMDSGATVVFNPSPEEMYLKGN
                     CTTINVSGLTDFLCGAKRPVHFGGVCLVVSKFLNIVTPDKAYFGEKDAQQLAVIKRMV
                     KDLNIDTEIIGCPIIRENDGLAKSSRNTYLSEEERKSALILNKSLSLAKEELVKGNLN
                     PENIKELITAKINSEHLAKIDYVEIVDSETLQPVKQIEHSILVAIAVFIGKTRLIDNF
                     TFELNI"
BASE COUNT         1229 a          357 c          468 g          982 t
ORIGIN      
        1 aaagcattaa tttctaaaaa catcataatt tttctaatag acttaatcac ttttaatata
       61 tatagtaaaa caaaaaactt atattttata aatatcataa tttttttact gatattttat
      121 tatataaatt ttatagaatt aattgtcaat tttttatgaa aatggtaaga tatttatgga
      181 tggtatcttg ttataagaac tatactttaa atgtttttaa ttattttgtc ttatgtaact
      241 catatcctca ggaatgagat tagaaattaa gatgttgtat cacaaagtgg aggtgatact
      301 attaaaatag gctttattgg ttctggaaaa gttggaacat ctttggcaaa ttatttttta
      361 tcaaaaggtt attgtgtttc aggcttttat ggaaggaatc aattatcttt attagaatca
      421 acaaatttaa caaaaacaaa gatttacagc aatttgaaag atataattta tgaaaacgat
      481 atattattta ttacaacatc agatgattct attgaaatta tagacaaaaa actttccaaa
      541 tttaatttaa aacataaata catttgccac acaagtggct ctttaaaatc tagtatattg
      601 ttctgttcaa aaaaagcagg tgcattaatt tattctatcc atcctatatt tgcattttcc
      661 aataaaaata ctgacataaa aaaaatgaaa gacatttgtt tttccataga aggtgataat
      721 gaacaagatg atttagttat tcaaaatttc atagatgatt tgggaaacca attttttata
      781 agagataagg atacttcatc cacttatcat ttagctaatg ttttagtttc aaatttagta
      841 ttatctttac tagatatagg agtaagttac tttattaaat taggtttatc tgaagaggaa
      901 tctttaaaag ctatcagtcc tttagtaaaa aaaaacatag aaaatatact tgataatggc
      961 tttactaaag ctcttactgg tcctgtttct cgtggagata taacaccaat aaggaaacat
     1021 ctatctgtat tggataaaaa agatgaggat atttacaaaa tactatcctt aaacctacta
     1081 aaaataattg ccttaggaaa tgacaattca ttaaaaggta taaaaaatat tactatagaa
     1141 aatgcaatcg aaaatttaat aagtaaatct gaaaaataca aagaaattta caaactttta
     1201 ggaggaaaaa acgatgaaaa ataccataca gacttttaag aatgctaaat atgaaggaaa
     1261 aaaactatct atgcttactg cttatgacta ctcaattgca aaaataatgg atgagtgtga
     1321 tataaatggt attttaatag gagattcatt aggaatggtc ataaaaggtg aagaaaacac
     1381 tctatctgtt accatagacg aaattatata tcatacaaaa gctgtaaaaa atggcgtaaa
     1441 aaatgcctta atcgtaagtg atatgccttt tctatcttac catgtttcta tagaagatgc
     1501 agttaaaaac gctggtagac ttataaaaga aggaggagct catgctgtaa agttagaagg
     1561 tggctcaaac gttataaagc aaatagaaag cattgtaaat gctcaaatac ctgtaatggg
     1621 gcatttagga ttaactcctc aatcagtaaa ttcatttggt gggtttaagg ttcaaggaaa
     1681 taccagtgaa acagcaagac aacttattga agatgctaaa ttaatagaaa aagcaggtgc
     1741 attctctatt gtccttgaag gagtgcctac gaaaatagct gagatggtaa ctaattctat
     1801 ttcaattcct acaataggta taggggcagg aattaactgt gatggacaaa ttttagttta
     1861 tcaagatatg ttgggaatgt ttggagattt tgttcctaag tttgtaaagc agtatgcaaa
     1921 tataggagat ataataaaag attcaattaa aaattacatc ctagaagtta atacaggtgc
     1981 atttccacaa gaaaaacaca gcttttcaat aaatgaatct gagttagaaa aattatacta
     2041 atattaagga tggtacaaaa tgcttgtaaa agaaattaaa ttactaagaa atataatcaa
     2101 agattggaga aaacatggct attctatagg ccttgttaca acaatgggat ttttacatga
     2161 aggacaccaa agtcttataa aaaaagctgt aaaagaaaat gataaagtag tagtgagtat
     2221 atttgtaaat ccaactcaat ttggaccaaa tgaagatttt aatagctatc caagagatat
     2281 agataaagat tttaaatatt gtatggatag tggagcaaca gtagtcttta acccatcacc
     2341 agaagaaatg tatttaaaag gtaattgtac taccattaac gtttctggac ttacagattt
     2401 tctttgtgga gctaaaagac ctgttcattt tggaggtgtc tgcctagttg tttcaaagtt
     2461 tctaaatata gtaacacctg ataaagctta ttttggagag aaggatgccc aacaattagc
     2521 tgtaattaaa agaatggtca aggatttaaa catagataca gaaataatag gctgtcctat
     2581 aattcgtgaa aatgatggat tagcaaaaag ttcgagaaat acatatctct ctgaggaaga
     2641 acgaaaatct gctctaatat taaataagag cttaagttta gcaaaagaag aattagtaaa
     2701 aggcaatcta aatccagaga atataaaaga attaataaca gctaaaataa attctgaaca
     2761 cttagcaaaa atagactatg ttgaaattgt agatagtgag acattacaac ctgttaagca
     2821 aatagaacat tctatacttg tggcaattgc tgtgtttata ggaaaaacca gactaattga
     2881 taattttaca tttgagttaa atatatagtc tataatttta tataatatat ctaaaaaata
     2941 atagaatacc taaaaagtaa taaattacct aaaaaataat aaattgctta gaaaataata
     3001 gattacaata actaaaattt taaaattaaa ttcctt
//
LOCUS       DAYAOO010000185         2940 bp    DNA     linear   BCT 12-OCT-2024
DEFINITION  TPA_asm: Clostridioides difficile isolate ST8-SSI-h139-18
            SAMN40601845-rid21577343.denovo.189, whole genome shotgun sequence.
ACCESSION   DAYAOO010000185 DAYAOO010000000
VERSION     DAYAOO010000185.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN40601845
            Sequence Read Archive: SRR28438827
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 2940)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2940)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-MAY-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-MAY-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002157583.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002157583.1
            Genome Coverage       :: 163x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/11/2024 16:19:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 4,038
            CDSs (total)                      :: 3,963
            Genes (coding)                    :: 3,930
            CDSs (with protein)               :: 3,930
            Genes (RNA)                       :: 75
            rRNAs                             :: 6, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 60
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 33
            CDSs (without protein)            :: 33
            Pseudo Genes (ambiguous residues) :: 0 of 33
            Pseudo Genes (frameshifted)       :: 7 of 33
            Pseudo Genes (incomplete)         :: 25 of 33
            Pseudo Genes (internal stop)      :: 11 of 33
            Pseudo Genes (multiple problems)  :: 8 of 33
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2940
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN40601845-rid21577343.denovo.189"
                     /isolate="ST8-SSI-h139-18"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Denmark"
                     /collection_date="2018"
                     /collected_by="Statens Serum Institute"
     gene            69..437
                     /locus_tag="ACGI5H_003895"
     CDS             69..437
                     /locus_tag="ACGI5H_003895"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420376.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="metalloregulator ArsR/SmtB family transcription
                     factor"
                     /protein_id="HFG9699566.1"
                     /translation="MENLVKIFKALSDETRLNILILVSKRNICQKGISKYLGISDSAV
                     SQHIKILKDVGIITGYKEGYYVLYHINKESFNICVDFINSMLSNSSESFIDVFDVNTI
                     HLGCSKECKSIKKCCKRREK"
     gene            440..811
                     /locus_tag="ACGI5H_003896"
     CDS             440..811
                     /locus_tag="ACGI5H_003896"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420377.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NifB/NifX family molybdenum-iron cluster-binding
                     protein"
                     /protein_id="HFG9699567.1"
                     /translation="MKVCIPVEENKGLDSKPYGHFGSAPIFVVCDLESGEVKSLDNGD
                     LDHEHGKCQPLKALSGTAVDAVVVGGIGQGAIIKLNGMGIKVYRAEGDTISANLDLLK
                     NGKLVEFPSDHTCSHDGCGHH"
     gene            complement(956..1411)
                     /locus_tag="ACGI5H_003897"
     CDS             complement(956..1411)
                     /locus_tag="ACGI5H_003897"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430160.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9699568.1"
                     /translation="MNINTVQGDSIEVLLRQLGATRISKVSSTLYFIKFDLGDGWEIS
                     YTYNINAKDQYFLQRIEPYPIGRGLFNDEYEIVSFISKDLKKFLNAKNSSNFKTFVEV
                     TRKVNSIIDNVEELFLNYNVDGDDLKTLNKELNDILNDIDYIEKHTKKI"
     gene            complement(1450..2715)
                     /locus_tag="ACGI5H_003898"
     CDS             complement(1450..2715)
                     /locus_tag="ACGI5H_003898"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430161.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ArsB/NhaD family transporter"
                     /protein_id="HFG9699569.1"
                     /translation="MEFQQIIAICIFLIVMAAIITEKVNRSVAAVGGALLMIIFNILT
                     LDEGLSHIDFNTIGVLVGMMLFVAVVKNSGLFEYIAIWTAKKAKGDPWKIMICFAIIT
                     AILSAVLDNVTTVLLIGPMTIVITQILGLNPVPFLITQILASNIGGTATLIGDPPNIM
                     IGSAANLSFMDFVINLGPAVIVILAITIICFRFIYGKELVVNERAKNAILKLDEKKSV
                     KDKPLLIKSLILIAFILFGFMFHSTIHIDSSVVALTGASIMLLIGKQDVDEIMAGIEW
                     STILFFMGLFVVVGGLVEVGIINKLAQALIGLTEGHLVFTMLLILWLSAIVSSFLDNI
                     PFVATLIPLILTMQAEGIDVMPLWWATSLGACLGGNGTLIGASANVVLAGIGNKHGHP
                     ISFKEYFKIGFPLMIISIIISTVYLIIKF"
BASE COUNT         1088 a          411 c          406 g         1035 t
ORIGIN      
        1 tggttgaaaa atctaattaa gagtactata atttaattaa gtaattactt aatcaaaatg
       61 aggtacttat ggaaaacttg gttaaaatat ttaaagcatt gagtgatgaa actagactta
      121 acatacttat attagtatcc aagagaaata tatgtcaaaa ggggatttct aaatatctag
      181 ggatttcaga ttctgctgtt tcacaacata taaaaatatt aaaagatgtt gggataataa
      241 caggatataa agaaggatac tatgttttat atcatattaa taaagaatca tttaatatat
      301 gtgtagattt tataaattct atgttaagta attctagtga aagctttata gatgtatttg
      361 atgtaaatac aatacatcta ggatgcagta aagaatgtaa atctataaaa aaatgttgta
      421 agagaaggga gaaataataa tgaaagtatg tataccagta gaggagaata aaggattgga
      481 tagtaaacca tatggacatt ttggttctgc tccaattttt gttgtgtgtg atttagaaag
      541 tggagaagtt aaatctttag ataatggaga tttagatcat gaacatggaa aatgtcaacc
      601 attaaaagca ttgtcaggga cagctgtaga tgcagtagtt gttggaggaa taggacaagg
      661 agctataatt aaattaaatg gaatgggaat aaaagtttac agagcagaag gtgatactat
      721 aagtgctaat ttagacttac ttaaaaatgg aaaattagta gaatttccat cagaccatac
      781 ttgctcacat gacggatgtg gacatcatta aaaaaaaaca gctgatgaaa tatatacttc
      841 atcagctatt ttttctttta ataaatacga ttttattctt ttaaaaccaa aatttagatt
      901 tttatgtttt ttgtagtatc cttaataata tttcaagttt acaagtttac tacttttaga
      961 ttttttttgt atgtttttct atatagtcaa tatcatttaa tatgtcattg agttctttat
     1021 taagtgtttt taaatcatca ccatctacat tgtagtttaa aaatagttcc tctacattat
     1081 caatgataga attgactttt ctagtaactt caacaaatgt cttaaagtta ctactatttt
     1141 tagcatttag aaattttttt aaatcctttg atataaatga tactatttca tattcatcat
     1201 taaatagacc tctaccaata ggatatggtt caattctctg taaaaaatat tggtctttag
     1261 cattaatatt ataagtataa gatatttccc aaccgtctcc taaatcaaac ttgataaaat
     1321 ataatgtact acttactttt gatattcttg tggcaccaag ctgtcttaaa agaacttcaa
     1381 tcgaatcacc ttgaacagta ttaatattca tatatacaca tcccctttag tattattata
     1441 ctatattttt taaaatttta taattaaata aacagtagat ataataatag atataatcat
     1501 aagtggaaaa cctattttga aatactcctt aaaagagata ggatgaccgt gtttattacc
     1561 tatacctgct agtacaacat tagcagatgc tcctattagt gttccatttc ctccaagaca
     1621 agctccaaga gatgttgccc accatagtgg cattacatca ataccttcag cttgcatagt
     1681 caaaataaga ggaattagtg ttgcaacaaa tggaatatta tctaagaaag aagagactat
     1741 agctgacaac cataatatca acaacattgt aaatacaaga tgtccttctg taagtccaat
     1801 caatgcttga gccaatttgt ttattatccc aacttctact aatccaccaa ctactacaaa
     1861 taatcccata aagaataaaa ttgtagacca ttcaatacct gccataattt catctacatc
     1921 ttgttttcct attaaaagca ttatagatgc tcctgtcagt gctacaacag aagaatctat
     1981 gtggattgta ctgtgaaaca taaaaccaaa aagtatgaat gctattaata taaggctttt
     2041 tataagtaga ggtttatctt taacagattt tttttcatct agttttaata ttgcattttt
     2101 agctctttca ttcacaacaa gttcttttcc ataaataaat ctaaagcata ttatagttat
     2161 agcaagtatt actataacag caggacctaa atttattaca aaatccataa aactaagatt
     2221 ggcagcacta ccaatcataa tatttggagg gtctcctata agagtagctg ttcctcctat
     2281 atttgaagct aaaatctgtg ttattaaaaa tggaactgga ttaagtccta atatttgtgt
     2341 aataactata gtcattggtc caataagtaa gacggttgta acattatcta atacagctga
     2401 taaaatagct gttataatag caaaacaaat cattatcttc catgggtcac ctttggcttt
     2461 ctttgcagtc cagatagcta tatattcaaa taaccccgag tttttgacaa cagctacaaa
     2521 tagcatcata ccaactaata caccaatagt attgaaatct atatggctta atccttcatc
     2581 aagtgtaagt atattgaata ttatcattaa tagtgcacca ccaacagctg ctacggatct
     2641 gtttaccttt tctgtaataa tagctgccat aactattaaa aatatacata tagctattat
     2701 ttgttgaaat tccataatat aagtacctcc atttgtatta ttttgtgcct aatgctagta
     2761 ctatatatag tattactttt ttattgtttt ttcaatggat gtatgaaagt atattattta
     2821 acaaagtttt tggaaaattg acagaattta aagaaaattt ttgttattta aataaatttt
     2881 aaaattattc cattgataat aatattaaac gacaaacgaa aaaatatacc ctttaaacta
//
LOCUS       DAYAOO010000186         2931 bp    DNA     linear   BCT 12-OCT-2024
DEFINITION  TPA_asm: Clostridioides difficile isolate ST8-SSI-h139-18
            SAMN40601845-rid21577343.denovo.190, whole genome shotgun sequence.
ACCESSION   DAYAOO010000186 DAYAOO010000000
VERSION     DAYAOO010000186.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN40601845
            Sequence Read Archive: SRR28438827
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 2931)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2931)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-MAY-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-MAY-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002157583.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002157583.1
            Genome Coverage       :: 163x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/11/2024 16:19:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 4,038
            CDSs (total)                      :: 3,963
            Genes (coding)                    :: 3,930
            CDSs (with protein)               :: 3,930
            Genes (RNA)                       :: 75
            rRNAs                             :: 6, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 60
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 33
            CDSs (without protein)            :: 33
            Pseudo Genes (ambiguous residues) :: 0 of 33
            Pseudo Genes (frameshifted)       :: 7 of 33
            Pseudo Genes (incomplete)         :: 25 of 33
            Pseudo Genes (internal stop)      :: 11 of 33
            Pseudo Genes (multiple problems)  :: 8 of 33
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2931
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN40601845-rid21577343.denovo.190"
                     /isolate="ST8-SSI-h139-18"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Denmark"
                     /collection_date="2018"
                     /collected_by="Statens Serum Institute"
     gene            <1..1126
                     /locus_tag="ACGI5H_003899"
     CDS             <1..1126
                     /locus_tag="ACGI5H_003899"
                     /EC_number="3.6.4.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454237.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004386 - helicase activity [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /codon_start=2
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HFG9699570.1"
                     /translation="KGKITMDFKSLGISENTINILKKSGITTPTPIQKESIKLIKEGK
                     DVIAEAQTGTGKTLAFLLPIFENISLDINDIQVLILSPTRELAIQITEEAMKLKESKD
                     VSILAAYGGKDIGSQIKKLKGNIHMIIATPGRLLDHLNRKTIDLSKLKTFVLDEADQM
                     LLMGFKNEVEAILKETSNKKQTLCFSATINSQVKKLAYRYTKNPVVVSIQKEEITLNN
                     IKQEVVETTDRKKLDALCKVLDEDNPFMAIIFCRTKRRVDNLEEALAIRGYNCQKLHS
                     DIAQSKRERIMKSFRNLDIQYLIATDVASRGLDISGVSHIYNYDLPETPEDYIHRIGR
                     TGRAGEEGYTCAFIDPKNERMLSEIETAIESKISRRIIEL"
     gene            complement(1503..2687)
                     /locus_tag="ACGI5H_003900"
     CDS             complement(1503..2687)
                     /locus_tag="ACGI5H_003900"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004453637.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9699571.1"
                     /translation="MQKSVKKAKVTGSMLAIFGVASVLFSSHAGGGFATGNQETQYYV
                     QYGWTAPLMAILAMIILTATMREVIIMYNNNNCRNYKDLFCELWRPYPKLEIIWEIYY
                     YLMVLIAVSAVIAGAAAVFQSIGVNYFVAVFIIGVVLLVFTIFGAMLVSKAATAMTIA
                     ILVCTLTIFIVGIKAKVPEITEILSNRTSFTPGYIKPILNTFIYAGFQSVVIPTLAGC
                     SRPLLKNSKEATKAMIISFVMNAIALGLAVTMLMGWYREIIAAGQTTLPTLYVAGQSG
                     NHTIYIIYNVALFLCLMSTGVTTIFGLVNRFEDHKALSFLSSRMKRRVFTACAIMVVS
                     MLISLTGLSNIVKYGYGYCGYLGLFTIVIPFLTLGHYKNKKFAKENPEAKWPAELNEN
                     VN"
BASE COUNT         1106 a          442 c          402 g          981 t
ORIGIN      
        1 gaaaggtaag ataacaatgg atttcaaaag cttagggatt agtgaaaata caataaatat
       61 tctaaaaaaa tcaggaataa caacacctac acctatacaa aaagaaagta ttaaactaat
      121 aaaagaagga aaagatgtaa tagcagaagc tcaaactgga acaggaaaaa cactagcttt
      181 tttacttccg atatttgaaa atatatcatt agatataaat gatatacaag tacttatact
      241 ttctcctaca agagaactag ctattcaaat aacagaagaa gctatgaaac ttaaagaatc
      301 taaagatgta agtattcttg cagcatatgg aggaaaagat attggttctc aaataaagaa
      361 actaaaagga aatattcata tgattatagc tacaccaggt aggcttttag accatctaaa
      421 tagaaaaaca atagacctta gtaagttaaa gacttttgtt ttagatgaag cagaccaaat
      481 gttgcttatg ggatttaaaa atgaagtgga agctatttta aaagagactt caaacaaaaa
      541 gcaaacacta tgcttttctg caactataaa ttctcaagta aaaaaattag cttatagata
      601 cacaaaaaat cctgttgtag tttctattca aaaagaagaa atcactctta ataatataaa
      661 acaagaagta gtagaaacta cagatagaaa aaaattagat gccttatgta aggtactaga
      721 tgaagataat ccttttatgg caataatatt ttgtagaact aagagaaggg ttgacaatct
      781 tgaagaagct cttgctataa gaggatataa ttgtcaaaaa cttcatagtg atattgctca
      841 atcaaaacga gaaagaataa tgaaatcatt tagaaattta gatatacaat acttaatagc
      901 tacagatgta gcttctcgtg gtcttgatat atctggagta agtcatatat ataattacga
      961 tttaccagaa acaccagaag actacatcca ccgtattggt agaactggta gagctggtga
     1021 agaaggctat acatgtgctt ttattgaccc taaaaatgaa cgaatgttaa gtgaaataga
     1081 gacggctata gaatctaaaa ttagtagaag aattatagaa ttataattta tagattgctt
     1141 aaaataccaa tgccacacaa acactgtaat atatagaaag ctacagaaaa catgtatcaa
     1201 tctatacttt gctgttatac tattttatat taaagaaaaa agaggctatc caaagtagga
     1261 ttagtctctt ttattgtcaa aataatgaaa atatatttga cttcatataa aaaagagtgc
     1321 cttataaact aaaagtccat tttgagatac cctcttttta tcttttattc ttagttttat
     1381 attgcttgtt tatagttgtt taatattaga ttttgcaaat aatcttaata aacatgcaga
     1441 tatattatct atagtattct tatttatagt attctcttta gcaatatttt ttgctactac
     1501 atctaattta cattttcatt taattccgct ggccatttag cttctggatt ttcctttgca
     1561 aacttcttat tcttataatg tcctagtgta agaaatggaa ttactatagt gaatagacca
     1621 agataaccac aatatccata tccatattta acaatattac ttaatcctgt aagtgatata
     1681 agcattgaca ctaccattat tgcacaagct gtaaataccc ttcttttcat tcttgaagaa
     1741 aggaaagaaa gtgctttatg gtcttcaaat ctatttacaa gaccaaatat agtagttact
     1801 cctgtagaca ttaaacaaag gaataatgca acattataaa ttatgtatat agtatgattt
     1861 ccagattgac ctgcaacata aagagtaggg agtgttgttt gcccagcagc aataatttct
     1921 ctataccatc ccattagcat agttacagca agtcctaatg caattgcatt cataacaaat
     1981 gaaattatca ttgccttagt agcttctttt gagttcttaa gaagtggtct tgaacatcct
     2041 gcaagtgtag gtataacaac cgattgaaaa cctgcataaa taaaagtatt aagtattggc
     2101 ttgatatagc caggtgtgaa actcgttcta tttgataata tttcagttat ttctggtact
     2161 ttagctttta taccaacaat aaaaatagta agagtacata ctagaatagc tattgtcatt
     2221 gctgtagctg ctttagatac aagcatagca ccaaatatag taaagacaag aagtacaact
     2281 ccaataataa atacagctac aaaataattt actcctatac tttgaaatac tgctgctgca
     2341 cctgctataa cagcacttac agctattaaa accattagat agtaatatat ctcccatatt
     2401 atttcaagtt ttggatatgg tctccaaagc tcacaaaata aatccttata attcctacaa
     2461 ttgttattat tatacattat gataacttct ctcatggtag cagtaagtat aatcattgct
     2521 aaaattgcca taagtggtgc tgtccatcca tactgcacat agtactgagt ttcttgattc
     2581 cctgtagcaa atcctcctcc tgcatgtgaa ctaaaaagaa cgcttgcaac accaaaaata
     2641 gctaacatag agcccgttac ttttgctttc tttacacttt tttgcatgaa atcatcctcc
     2701 ctaaaatgat attgaaagtt tttattttaa cactttattg ataaaacaat aacatttttg
     2761 ctcattaaat tcaactatat ttttccaatg actttacatt ttcaacttat ttccaccttt
     2821 atattaaata ttttttatat atttatttta ttttttaaat agtattcaaa ttcactttgt
     2881 tttttaattt tatgaaatat cttttttaat gttaaatatt atacattttt t
//
LOCUS       DAYAOO010000187         2655 bp    DNA     linear   BCT 12-OCT-2024
DEFINITION  TPA_asm: Clostridioides difficile isolate ST8-SSI-h139-18
            SAMN40601845-rid21577343.denovo.191, whole genome shotgun sequence.
ACCESSION   DAYAOO010000187 DAYAOO010000000
VERSION     DAYAOO010000187.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN40601845
            Sequence Read Archive: SRR28438827
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 2655)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2655)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-MAY-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-MAY-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002157583.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002157583.1
            Genome Coverage       :: 163x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/11/2024 16:19:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 4,038
            CDSs (total)                      :: 3,963
            Genes (coding)                    :: 3,930
            CDSs (with protein)               :: 3,930
            Genes (RNA)                       :: 75
            rRNAs                             :: 6, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 60
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 33
            CDSs (without protein)            :: 33
            Pseudo Genes (ambiguous residues) :: 0 of 33
            Pseudo Genes (frameshifted)       :: 7 of 33
            Pseudo Genes (incomplete)         :: 25 of 33
            Pseudo Genes (internal stop)      :: 11 of 33
            Pseudo Genes (multiple problems)  :: 8 of 33
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2655
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN40601845-rid21577343.denovo.191"
                     /isolate="ST8-SSI-h139-18"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Denmark"
                     /collection_date="2018"
                     /collected_by="Statens Serum Institute"
     gene            complement(208..1020)
                     /locus_tag="ACGI5H_003901"
     CDS             complement(208..1020)
                     /locus_tag="ACGI5H_003901"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HFG9699572.1"
                     /translation="MFSIGMFSKINKITTKTLRYYEDIGLLKPEYVDEFTKYRYYTTE
                     QLPKLHQIITLKQMGLSLAEIKKAVENPEEVENILMNKEKEMLDVIKSEEYKIIKLRN
                     YLMNLKGEVNMNDVIIKSLPKVKVASMRKVLKGYDELFNLFPNVMAEEMMKTGCTCAV
                     PDYCFNIYHDGEYRETDMDVEMCQAINDLKEDTDILKFKELDAVENAVCILHNGPYST
                     LGKTYADAFKWIEDNKYKVVGNPRESYIDGIWNKESEEDWLTEVQIPVKRML"
     gene            complement(1096..2514)
                     /locus_tag="ACGI5H_003902"
     CDS             complement(1096..2514)
                     /locus_tag="ACGI5H_003902"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0008324 - monoatomic cation transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0006813 - potassium ion transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="potassium/proton antiporter"
                     /protein_id="HFG9699573.1"
                     /translation="MTELMIISGLVLLICITSSKVLYKFGVPILLIFILLGMLFGSDG
                     MVGIYFDNYELTKQLCSIGLIFIMFFGGFGTNWNMAKPVAIPSILMSSLGVIITAGVT
                     GMFCHMVIGTSLLEGLLIGAIAASTDAASVFAVLRSQKLNLKGSLASLLEVESGSNDP
                     IAYMLTLILLTLMNNSGVELIAPMVIKQIAFGLAIGFILAKLSVYILRHSNFEIEGFY
                     TIFITAIAILSYAFSEYLGGNGYLSVYISGIIIGNSRIPLKKSLVHFFDGISWIMQIM
                     LFFMLGLLSFPSKLPNVFGIAMAISIFMIVIARPLATFIVLAKFKFSNKEKLFISWVG
                     LRGAASVVFAIYAVTQGVAIENDIFHIIFFIALLSVGIQGSLIPTVARKLDLVDDNTP
                     VLKTFNDYDGEISSKLIEVNVDEGNKWANKSIIDSNIPDDILIVMIKRKEQVLIPKGS
                     TIIKTGDILVLSGDRIEELIQL"
BASE COUNT          929 a          483 c          272 g          971 t
ORIGIN      
        1 ctttaataaa aatttataaa tagagcatct ttagaaaact attataataa aaaaataaga
       61 ggctgtctaa aaatatagat aagccttttt tcataatcgt aattataaaa atatacttga
      121 tttcatatga aaaagagtgt ctcataaact aaaatgttta ctttgagaca ccaccttttt
      181 tattcttatt tatactttgt agacatatta taacatgcgt ttcactggta tctgaacttc
      241 tgtcaaccag tcttcttcac tctctttatt ccatatacca tctatataag attctctagg
      301 atttccaacc actttatatt tattatcctc tatccattta aatgcatctg cgtaagtttt
      361 tcctaatgtt gaatatggac cattgtgtaa tatacaaact gcattttcaa ctgcatctaa
      421 ttctttaaat tttaatatat ccgtatcttc ctttaaatca tttatagctt gacacatttc
      481 aacatccata tcagtctctc tatattcacc atcatgatat atattaaaac aataatcagg
      541 aactgcacat gtacaccctg ttttcatcat ttcttcagcc attacatttg gaaatagatt
      601 aaaaagttca tcatacccct ttaacacttt tctcatagaa gcaactttaa cttttggtaa
      661 agacttaata attacatcat tcatattgac ttctcctttc aaattcataa ggtaattacg
      721 tagtttaatt attttatatt cttcactttt aattacatcc aacatttctt tttctttatt
      781 cattaaaata ttttcaactt cttcaggatt ttctacagct ttttttatct cagctaatga
      841 taaacccatt tgttttaaag ttattatctg atgtaattta ggtaattgct ctgttgtata
      901 atacctatat tttgtaaatt catctacata ttctggtttt aacaacccta tatcttcata
      961 ataccttaat gtctttgtag ttattttatt tattttagaa aacattccta tagaaaacat
     1021 ctcatcacct gcgcattaga tttgattaat ttaagtttaa actttcccct taggttaaag
     1081 tcaatacaaa ataaattata attgtattaa ttcttcaatt ctatctccac tcaataccaa
     1141 aatatcccct gtttttataa tggttgaacc tttaggtatt aaaacctgtt cctttctttt
     1201 tatcataact attaatatat cgtctggtat attagaatct attatactct tattagccca
     1261 tttattaccc tcatcaacat ttacttcgat aagtttagag ctaatttctc catcataatc
     1321 attaaatgtt tttaatacag gtgtattatc atcaactaaa tccaactttc tggctacagt
     1381 tggtatcaat gaaccttgta ttcctactga aagcaacgct ataaaaaata ttatatggaa
     1441 tatgtcattc tctatggcta ctccttgagt aacagcataa attgcaaaaa ctactgaagc
     1501 cgcacctcta agacctaccc acgatatgaa taatttttct ttatttgaga atttaaattt
     1561 tgctagaact ataaatgttg ctaatggtct tgcaataact atcatgaata tagatatggc
     1621 cattgctata ccaaatacat ttggtaactt agaagggaaa gataacaatc ctaacataaa
     1681 gaataacatt atttgcataa tccatgaaat tccatcaaag aaatgaacca aacttttttt
     1741 aagaggtatc ctactatttc ctataataat acctgaaatg taaacactta aatatccatt
     1801 tcctccaaga tactcgctaa atgcataaga aagtattgca atagctgtta taaatatagt
     1861 ataaaatcct tctatctcga agtttgaatg tcttaaaata taaacagata attttgctag
     1921 tataaatcct atagctaacc caaaagctat ttgttttatt accattggtg caataagttc
     1981 taccccagaa ttattcatca atgtcaaaag aattagtgtc agcatatacg ctattgggtc
     2041 attacttcca ctttcaactt ctaataatga tgcaagtgaa ccctttaagt ttagtttttg
     2101 agaacgcaac acagcaaaca cagatgcagc atctgttgaa gctgcaattg ccccaattaa
     2161 taaaccttca agtaaactag ttcctattac catgtggcaa aacatacctg taaccccagc
     2221 cgtaattatt acacccagtg aagacattaa tatagaaggt atagcaacag gtttagccat
     2281 attccagttt gttccaaacc ctccaaaaaa cattataaat attagtccaa tagaacataa
     2341 ttgttttgtc agttcatagt tatcaaaata gattcctacc atcccatcag acccaaataa
     2401 catccctagt aagataaaaa tcaataatat tggtactcca aatttataca ataccttgct
     2461 agaagttata caaatcaata gtactaaccc acttataatc attaattctg tcatagcatc
     2521 aactccattt catataaatt ttgtagatta atttacatct acaattttat tacttattca
     2581 aatataacat gacataaatt ttataagtta tggtacataa agttcaacaa aaatttcaca
     2641 atacattaaa atgtg
//
LOCUS       DAYAOO010000188         2616 bp    DNA     linear   BCT 12-OCT-2024
DEFINITION  TPA_asm: Clostridioides difficile isolate ST8-SSI-h139-18
            SAMN40601845-rid21577343.denovo.192, whole genome shotgun sequence.
ACCESSION   DAYAOO010000188 DAYAOO010000000
VERSION     DAYAOO010000188.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN40601845
            Sequence Read Archive: SRR28438827
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 2616)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2616)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-MAY-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-MAY-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002157583.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002157583.1
            Genome Coverage       :: 163x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/11/2024 16:19:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 4,038
            CDSs (total)                      :: 3,963
            Genes (coding)                    :: 3,930
            CDSs (with protein)               :: 3,930
            Genes (RNA)                       :: 75
            rRNAs                             :: 6, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 60
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 33
            CDSs (without protein)            :: 33
            Pseudo Genes (ambiguous residues) :: 0 of 33
            Pseudo Genes (frameshifted)       :: 7 of 33
            Pseudo Genes (incomplete)         :: 25 of 33
            Pseudo Genes (internal stop)      :: 11 of 33
            Pseudo Genes (multiple problems)  :: 8 of 33
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2616
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN40601845-rid21577343.denovo.192"
                     /isolate="ST8-SSI-h139-18"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Denmark"
                     /collection_date="2018"
                     /collected_by="Statens Serum Institute"
     gene            complement(221..1471)
                     /locus_tag="ACGI5H_003903"
     CDS             complement(221..1471)
                     /locus_tag="ACGI5H_003903"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418703.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1015 family protein"
                     /protein_id="HFG9699574.1"
                     /translation="MATIKPFKAIRPNKYIVDKVAALPYDVMNSKEARRIAEGNPYSF
                     LHIDKSEIDLDENIDLYDEKVYLKARENLDEFRKQEILVKDDKECIYIYKQIMDGRAQ
                     VGIVACISVDESLNGTIKKHEYTRPEKEIDRTKHIKYCDANTGTILVTYKHQRVIDDI
                     INDFMDNNEPLYDFITDDKIEHTVWKIDNDDIIDNLVDKFEKLDYLYIADGHHRTASA
                     ENVAKEMRAKNPNYTGKEEFNYFIAMIAPDENLMVLDYNRVIKDLNGLSEEEFINKIK
                     ENFELEEIEGKEKYKPDKKGTFGMYLGDKWYKMKANKNLLEIEDPVDSLDISILQDYV
                     IDAILGIDNPRVDKRIDFIGGIRGLEELEKRVNEDMKVAFAMYPTSIEDLIRVADANK
                     IMPAKSTWFEPKVRCGLFLHEINE"
     gene            complement(1503..2444)
                     /locus_tag="ACGI5H_003904"
     CDS             complement(1503..2444)
                     /locus_tag="ACGI5H_003904"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437082.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-2-hydroxyacid dehydrogenase"
                     /protein_id="HFG9699575.1"
                     /translation="MYNILVTDGIEKEAARKLRELDFNVIEQFYEKDVLGDKLKDVDV
                     LVVRSATKVTKDVIDKALEGKKLKLIVRGGVGLDNIDVKYAQANGIKVMNTPNASSIS
                     VAELTIGQLFVLARFINTANVTMRDGKWEKKKYKGTEINGKTLGLIGFGRIAKEVAKR
                     AELLGMNVIYTDIMGEAQGFNNYKFCDMEEVLENADFLSLHIPFDKNKGAVITEKEIN
                     KMKKGAYLINCARGGLVDEKDLLKALDEGKLSAAAIDVYEQEPTLNLDLVNHPRVSPT
                     PHIGASTVEAQERIGDEIVNVIQDFFLDFNNLIGVAL"
BASE COUNT          788 a          496 c          244 g         1088 t
ORIGIN      
        1 acatttaaaa ccttataaat atacaaatac aattatatga attttcatcc tcaattatag
       61 catagaatat gactatctat atcctaaaat tatccatttc taaaaaaaag gtaactatta
      121 ttaagaatat caacttatag aatttatatt ccacatacga ttttcaatca aaaaaacaag
      181 ggctaaaaag tgaattgtgc actttttagc cctttattaa ttattcattt atttcatgta
      241 agaatagacc acatcttact ttaggttcaa accatgttga cttagctggc attatcttat
      301 ttgcatctgc tactcttatt aaatcttcaa tactagtagg atacattgca aatgctactt
      361 tcatatcttc attaactctt ttttctaatt cttcaagacc tctaattcca ccgataaaat
      421 caattctttt atctactcta ggattatcaa ttcctaaaat agcatcaata acatagtctt
      481 gtaatataga aatgtctaat gagtcaacag ggtcttctat ttctaataaa tttttatttg
      541 ctttcatttt ataccactta tcacctaggt acattccgaa agttcctttt ttgtcaggtt
      601 tatatttttc ttttccttct atttcttcta gttcaaaatt ttcttttatt ttatttataa
      661 attcttcctc gcttaaacca tttaagtctt tgataaccct attataatcc aaaaccatta
      721 aattctcatc tggtgcaatc attgctatga agtaattaaa ttcttctttt ccagtataat
      781 ttggattttt agctctcatt tctttggcta cattttctgc tgaagctgtc ctatgatgac
      841 catctgcaat gtatagataa tctaattttt caaatttatc tactaggtta tctattatat
      901 catcattatc aatcttccat actgtatgct ctatcttgtc atctgttatg aaatcatata
      961 aaggttcatt attatccata aaatcattga ttatatcatc tatcaccctt tgatgtttgt
     1021 aagttacaag tatagttccc gtattagcat cacagtattt tatgtgttta gttctatcaa
     1081 tttccttttc tggtcgagtg tactcatgtt tttttattgt tccattcaag ctttcatcaa
     1141 ctgatataca tgctactata ccaacttgag ctctaccatc catgatttgt ttatatatat
     1201 atatacactc tttgtcatct tttactagaa tttcttgttt tcgaaactca tctaaatttt
     1261 ctcgcgcttt taaataaact ttttcatcat ataaatctat attttcatct aaatcaattt
     1321 ctgatttatc tatatgcaaa aatgaatatg gattcccttc tgcaattctt ctagcttctt
     1381 tactattcat aacatcgtaa ggaagtgctg ctactttatc tactatatat ttatttggtc
     1441 taatcgcctt aaatggttta atcgttgcca ttactaattt cctcctaatt atacaaaata
     1501 ttttataatg ctacccctat tagattgttg aagtcaagaa agaaatcttg aatcacattt
     1561 actatttcgt ctcctattct ttcttgagct tctactgtag atgccccaat atgaggtgta
     1621 ggagaaactc ttggatgatt tactaagtct aaatttaatg taggttcttg ttcataaaca
     1681 tctatagcag ctgctgataa tttaccttca tctaatgctt ttagtaaatc tttttcatca
     1741 actaaaccgc ctcttgcaca gtttattaaa taagcccctt tcttcatctt atttatttct
     1801 ttttcagtta ttactgcccc cttattctta tcaaatggta tgtgtaaaga taagaaatct
     1861 gcattttcta aaacttcttc catatcacag aatttataat tgttaaagcc ttgcgcctca
     1921 cccattatgt cagtatatat aacattcata cctaataatt ctgctctctt tgcaacttct
     1981 tttgcaattc ttccaaaacc tataagtcca agtgtctttc cattaatttc tgtaccttta
     2041 tactttttct tctcccattt tccatctctc atagttacat ttgcagtatt tatgaatctt
     2101 gcaagaacaa ataattgacc tattgtaagc tctgcaacag atatactgct tgcatttgga
     2161 gtattcataa cttttatgcc attagcttga gcatatttaa catctatatt atccagacct
     2221 actccacctc ttactatcaa cttcaacttt ttaccctcta atgctttatc tattacatct
     2281 ttagtaactt tagtagctga acgtactaca agtacatcaa catctttaag tttatctcct
     2341 aaaacatctt tttcataaaa ctgctctatc acattaaaat ctaactctct caattttctc
     2401 gctgcttctt tctctattcc atcagtaact aatatattat acataacaaa ctcctccaat
     2461 ttttattcac ttaatttttc caatttttat tttttaaagt attttcatca ataaaaaact
     2521 ttacttaatt taactttctg tttatataat tttcaaaata tttttttatt aaagtcatat
     2581 caaatttttc tattgtttgt taaaaattta atatgt
//
LOCUS       DAYAOO010000189         2547 bp    DNA     linear   BCT 12-OCT-2024
DEFINITION  TPA_asm: Clostridioides difficile isolate ST8-SSI-h139-18
            SAMN40601845-rid21577343.denovo.193, whole genome shotgun sequence.
ACCESSION   DAYAOO010000189 DAYAOO010000000
VERSION     DAYAOO010000189.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN40601845
            Sequence Read Archive: SRR28438827
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 2547)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2547)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-MAY-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-MAY-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002157583.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002157583.1
            Genome Coverage       :: 163x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/11/2024 16:19:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 4,038
            CDSs (total)                      :: 3,963
            Genes (coding)                    :: 3,930
            CDSs (with protein)               :: 3,930
            Genes (RNA)                       :: 75
            rRNAs                             :: 6, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 60
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 33
            CDSs (without protein)            :: 33
            Pseudo Genes (ambiguous residues) :: 0 of 33
            Pseudo Genes (frameshifted)       :: 7 of 33
            Pseudo Genes (incomplete)         :: 25 of 33
            Pseudo Genes (internal stop)      :: 11 of 33
            Pseudo Genes (multiple problems)  :: 8 of 33
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2547
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN40601845-rid21577343.denovo.193"
                     /isolate="ST8-SSI-h139-18"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Denmark"
                     /collection_date="2018"
                     /collected_by="Statens Serum Institute"
     gene            217..1836
                     /locus_tag="ACGI5H_003905"
     CDS             217..1836
                     /locus_tag="ACGI5H_003905"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423615.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_function: GO:0005436 - sodium:phosphate symporter
                     activity [Evidence IEA];
                     GO_process: GO:0044341 - sodium-dependent phosphate
                     transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Na/Pi cotransporter family protein"
                     /protein_id="HFG9699576.1"
                     /translation="MNIVISLIGGLGLFLYGMSLMGEGLQKSAGDKLKKIIELLTSNV
                     VMGVLVGTVVTGIIQSSSATTVMVVGFVNAGIMNLSQAIGVIMGANIGTTVTAQLVSF
                     NLEGIAPIALGIGILFYLFTSNQKTKHLSEILIGFGILFTGMEFMKDAVAPLAEYKAF
                     TDALLYFSKNPVLGILAGFAITGIVQSSSASMGMLIALASQGILPLSSALPILYGDNI
                     GTCVTSLLSSVGASRNARRAAVMHLSFNVIGTIIFMLVLNKPISAIVTHFDPTDTARQ
                     IANAHTLFNLTNVIILLPFSKYIVKLANRLIPIKETESEIVNNTKYLDERMFSTPSIA
                     LGNTVQEVVRMGHKATNSLEHSIAGFLNKSNEDINKAFESEKVVNKLQKDILNYLLKL
                     SKEPLRDDERFRTDLLFNTVNDIERVSDHAENIAELAMSVKEMNISFSDSAIREIYEI
                     YNKTITNFKDALIVLDVKDFELANKVLEVENEVNYLEKTFRNSHMIRLNNGSCTIDAG
                     VLYLDLLTNLERISDHSTNIVKQVLKLKQKI"
     gene            2210..2404
                     /locus_tag="ACGI5H_003906"
     CDS             2210..2404
                     /locus_tag="ACGI5H_003906"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423614.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide ABC transporter substrate-binding
                     protein"
                     /protein_id="HFG9699577.1"
                     /translation="MINYMVEIIYSEKISEVENMLKIENIQYEFTSRDGFIFFGFYDM
                     TDAYRFETLCSDEKIRFKRI"
BASE COUNT          946 a          296 c          374 g          931 t
ORIGIN      
        1 aatctaagtt caagtattta aattgctata tatcataaat tttctaaaat taacaacaac
       61 ttaaaaattt aacattctct taacgtatac ttaacaaaac attaatattt ttattgacaa
      121 aatttgttat tctatattat ggaaacaata aattttagtt aataaagttt ataattcaga
      181 taaaaaaatt attaatttct taagggagga aatatcgtga atatagtaat tagccttatc
      241 ggtggacttg gactttttct ttacggaatg agtttaatgg gagaaggttt acaaaaatca
      301 gcaggagaca aattaaaaaa aattattgaa ctcttaacaa gtaatgttgt tatgggtgta
      361 ctggtaggta cagtcgttac aggtattata caaagttcaa gtgctactac tgttatggtt
      421 gtaggatttg taaatgcagg tataatgaat ctaagtcaag ctattggtgt aataatgggg
      481 gcaaatatag gtactacagt tactgctcaa ttagtttcat ttaatcttga aggaattgca
      541 ccaattgctt taggtatagg tattttattc tatttattta catcaaatca aaaaacaaag
      601 catttatctg agatacttat aggtttcggt atattattta caggaatgga gtttatgaaa
      661 gatgcagtag ctccacttgc tgaatataaa gcattcactg atgcactttt atattttagt
      721 aaaaatcctg tattaggtat attggcagga tttgccataa ctggtattgt tcaaagttca
      781 agtgcatcta tgggtatgtt aatagcacta gcttctcaag gaatacttcc tctatcatct
      841 gctttaccta ttctttatgg agataatata ggtacttgtg ttacttcact tttatcaagt
      901 gttggtgcaa gtagaaatgc tcgacgtgca gctgtaatgc atttaagttt taatgtaatt
      961 ggtacaataa tatttatgct tgttttaaat aaacctatat cagccatagt tactcatttt
     1021 gacccaactg atacagctag acaaatagca aatgcacata ctttatttaa tcttacaaat
     1081 gttataatat tattaccatt ttctaaatac atagttaaat tagcaaatag acttatacct
     1141 attaaagaaa ctgaatcaga aatagtaaat aatactaagt acttagatga aaggatgttt
     1201 agcactccat ctatagcact tggtaatact gtacaagaag ttgtaagaat gggtcataaa
     1261 gctacaaact ctttggaaca ttcaattgca ggatttttaa ataagagcaa tgaagatatt
     1321 aataaagctt ttgagtcaga aaaagttgtc aataagttac agaaagatat attgaactat
     1381 ttgttaaaac tttctaaaga acctcttaga gatgatgaac gctttagaac agatttgctt
     1441 tttaatactg taaatgacat tgaaagagtc tctgaccatg cagaaaatat agctgaattg
     1501 gccatgagtg ttaaggaaat gaacattagt ttttctgata gtgcgataag agaaatatac
     1561 gaaatataca ataagacaat tactaatttt aaggatgcct taatagtttt agatgttaaa
     1621 gattttgagt tagcaaataa agttttagaa gttgaaaatg aagtaaatta tttagaaaaa
     1681 acttttagaa attcacatat gattagacta aataatggaa gttgtacaat tgatgctggt
     1741 gtactttatc ttgacttact tactaatcta gaaagaattt ctgaccactc aacaaatata
     1801 gtaaaacaag tactaaaact taaacaaaaa atatagtgat tatttttata tataatctta
     1861 atcaatgaga agtaagaagc tatagataat gcttatatca tttatggctt cttatttttt
     1921 atgtaatact caaattttta tagtattctc ttattattaa acagtttctg cctagaatat
     1981 tccatatata tatgacttct ttcataaaac ttgaactgcc cataaataaa gtcacaagta
     2041 tacataacta ttttttaatc aattataacc aatatttgtt ttatttatct tcattttaat
     2101 tcttcattca ataatgtaat aatattattt tttatttgga tactattata tcatctaaat
     2161 atgttattat atatttggat attttcatat taataggagg gattctacaa tgataaatta
     2221 tatggtagaa attatatata gcgaaaaaat aagcgaagta gaaaacatgt tgaaaattga
     2281 aaatatacaa tatgaattta cttctcgtga tggctttata ttttttggtt tttatgatat
     2341 gacagacgca tatagatttg agactttatg ttcagatgaa aaaattcgat ttaaaagaat
     2401 ataatagata aaaaagtaca tatttctaaa ctatttgttt ttcaaattta ggttgtgttt
     2461 taatgtagtg ttgatattat aaacaatttt aataataaaa aagtagggac attatattaa
     2521 tatgctccta ctttttactc atactta
//
LOCUS       DAYAOO010000190         2447 bp    DNA     linear   BCT 12-OCT-2024
DEFINITION  TPA_asm: Clostridioides difficile isolate ST8-SSI-h139-18
            SAMN40601845-rid21577343.denovo.194, whole genome shotgun sequence.
ACCESSION   DAYAOO010000190 DAYAOO010000000
VERSION     DAYAOO010000190.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN40601845
            Sequence Read Archive: SRR28438827
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 2447)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2447)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-MAY-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-MAY-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002157583.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002157583.1
            Genome Coverage       :: 163x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/11/2024 16:19:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 4,038
            CDSs (total)                      :: 3,963
            Genes (coding)                    :: 3,930
            CDSs (with protein)               :: 3,930
            Genes (RNA)                       :: 75
            rRNAs                             :: 6, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 60
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 33
            CDSs (without protein)            :: 33
            Pseudo Genes (ambiguous residues) :: 0 of 33
            Pseudo Genes (frameshifted)       :: 7 of 33
            Pseudo Genes (incomplete)         :: 25 of 33
            Pseudo Genes (internal stop)      :: 11 of 33
            Pseudo Genes (multiple problems)  :: 8 of 33
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2447
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN40601845-rid21577343.denovo.194"
                     /isolate="ST8-SSI-h139-18"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Denmark"
                     /collection_date="2018"
                     /collected_by="Statens Serum Institute"
     gene            complement(177..1469)
                     /gene="brnQ"
                     /locus_tag="ACGI5H_003907"
     CDS             complement(177..1469)
                     /gene="brnQ"
                     /locus_tag="ACGI5H_003907"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438233.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0015658 - branched-chain amino acid
                     transmembrane transporter activity [Evidence IEA];
                     GO_process: GO:0015803 - branched-chain amino acid
                     transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="branched-chain amino acid transport system II
                     carrier protein"
                     /protein_id="HFG9699578.1"
                     /translation="MGEKQINFKDVIVIGFALFAMFFGAGNLIFPPYLGVLSGSSWLV
                     AFIGFLFADGGLALLAVIAATKFNGDTSKMFSRAGKGLSIALGCAMVICIGPLLAIPR
                     TAATTYEMGILPTIGSGISPVIFSIVFFALVLVLTIRPSKVVDIVGSILTPALLIALA
                     VLIVKGIVSPLGEIRDSSLIQNVFAEGITQGYQTMDALAASVFASIIIMSVIAKGYTG
                     EKEKMKATISAGVIAVIGMALVYGGLCYLGATVSQQYGQDVQQTALIVAITAALLGTT
                     GKILLAIIVALACLTTAIGLSSAAGQYFSTLTDGKLKYEHIVIVVCVFSAIISNFGVS
                     TIIQFSSPILSMVYPATITLVILALFSNKIKNDNVFKCAAYMALLVSVLTVATSFGVK
                     IPLVNSLPFASLGFNWIVPVVIAGIIGNFIPSKSSKTA"
BASE COUNT          823 a          391 c          253 g          980 t
ORIGIN      
        1 ttttttattt tattatcttt ataaatcata ctacttcaaa aataaatttt taaatttatc
       61 aaacaggatt aataatgttc ttttatctac aataatttaa taattctttt aaatataaaa
      121 aggaattgcc tatataattt aaaggcaatt ccataattat caattagttt ttattattat
      181 gcagttttac tgcttttaga tggaataaag tttcctatta ttcctgctat tacaactgga
      241 actatccagt taaatcctaa tgaagcaaat ggtaagctat taactagagg aatttttaca
      301 ccaaaacttg ttgcaactgt taatacactt actaataatg ccatgtatgc agcacatttg
      361 aacacgttgt catttttaat tttattacta aataatgcta gtataactag agttatagtt
      421 gctggatata ccatacttag tataggagaa gagaattgta ttattgtact tactccaaag
      481 tttgatatga ttgcactaaa tacacaaact actataacta tatgctcata ctttaatttt
      541 ccatctgtaa gtgttgagaa atattgacca gctgctgaag aaagacctat agctgttgtt
      601 aaacatgcta atgcaactat aatagccaat aaaattttac ctgtagttcc aagtaaagct
      661 gctgttattg caactattaa agctgtttgt tgaacatctt gtccatattg ttgagacaca
      721 gttgctccaa gataacataa tccaccataa actaatgcca ttcctattac tgcaattaca
      781 cctgcactta ttgtggcttt catcttttct ttctcacctg tataaccttt agctattact
      841 gacatgatta taattgatgc aaatacacta gctgccaatg catccattgt ttgataacct
      901 tgagttatac cttctgcaaa tacattttgt attaaagaac tgtctcttat ttctcctaat
      961 ggagatacga tacctttaac tattaatact gctaaagcta taagtaaagc tggagttaat
     1021 attgacccaa ctatatctac aacttttgat ggtcttattg ttaaaaccaa tactagagca
     1081 aagaatacta tagagaatat tactgggctt attccagaac ctattgtagg taatataccc
     1141 atttcataag ttgttgctgc tgttctaggt attgctaaaa gtggccctat acagattacc
     1201 attgcacatc ctaatgcaat acttaatcct ttgcctgccc ttgagaacat cttcgatgtg
     1261 tctccattga acttagttgc tgctataact gctaataatg ccaaaccacc atctgcaaaa
     1321 aggaatccta tgaaagctac tagccaacta cttccagata aaactcctag atatggaggg
     1381 aagattaagt tccctgcacc aaaaaacatt gcaaatagtg caaatccaat tacaattaca
     1441 tctttaaaat tgatttgttt ctcacccatt taaagcaccc ccatttgaat tttactacct
     1501 tttactaaaa aataagtcca atctcttaat taaatgaaaa ccttttgacg agattttatt
     1561 taattataca tttttgactt aaatttgtca attatgtttc ataatttata aaatcttcac
     1621 aatatttaat acaactttct taattaaaca aaatcaacct gtatacttta aacatagttg
     1681 gttttttgtt ttttctctaa tttttcttga taaaattaac tattccgaat aattaaaata
     1741 ttaagacttt ttagattatt cgatttatta ttaagttgta ttgctttata tactgtatat
     1801 atcactctcc ttttttacat tcatataatc tttttaattc aatttaaatt ttaaatattt
     1861 tgtgtttatt atataatctg aaaaaaaagc agtcaatagc atttttaatt tttttaattt
     1921 tcaaaattat gattcttaaa aaatcgtttt ccttttatca taacacctat ttacgttaat
     1981 tcttgtagta ttttgtattt attttgctaa attgacagtt aactttattc aatttttatt
     2041 ctacttgcgt agatttgcct cttgtttttt actcttaaaa ccattttttc tgaaaattcc
     2101 ttattatgat ttatcaactt atttttcttc ataacaatta ctctctaact tccaacttac
     2161 ttaaactttg cagttgctag tattcacgtt tacatactta tatgtcataa ttaactaaaa
     2221 attcttaata tatctctcaa tgaaaacaat ttactcattt atttaataca tttatataat
     2281 catatgtctt aaattttgtt ttattatttt attattgtca caattttatt tatattatat
     2341 ttttgtaaaa atcatttaat atgtatactt aaatttataa aattactcta aaattctttt
     2401 ttaatctcta ttattgttaa aaaataaacc atatattttt ttgatat
//
LOCUS       DAYAOO010000191         2313 bp    DNA     linear   BCT 12-OCT-2024
DEFINITION  TPA_asm: Clostridioides difficile isolate ST8-SSI-h139-18
            SAMN40601845-rid21577343.denovo.195, whole genome shotgun sequence.
ACCESSION   DAYAOO010000191 DAYAOO010000000
VERSION     DAYAOO010000191.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN40601845
            Sequence Read Archive: SRR28438827
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 2313)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2313)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-MAY-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-MAY-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002157583.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002157583.1
            Genome Coverage       :: 163x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/11/2024 16:19:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 4,038
            CDSs (total)                      :: 3,963
            Genes (coding)                    :: 3,930
            CDSs (with protein)               :: 3,930
            Genes (RNA)                       :: 75
            rRNAs                             :: 6, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 60
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 33
            CDSs (without protein)            :: 33
            Pseudo Genes (ambiguous residues) :: 0 of 33
            Pseudo Genes (frameshifted)       :: 7 of 33
            Pseudo Genes (incomplete)         :: 25 of 33
            Pseudo Genes (internal stop)      :: 11 of 33
            Pseudo Genes (multiple problems)  :: 8 of 33
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2313
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN40601845-rid21577343.denovo.195"
                     /isolate="ST8-SSI-h139-18"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Denmark"
                     /collection_date="2018"
                     /collected_by="Statens Serum Institute"
     gene            214..2226
                     /locus_tag="ACGI5H_003908"
     CDS             214..2226
                     /locus_tag="ACGI5H_003908"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888014.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0008134 - transcription factor binding
                     [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sigma 54-interacting transcriptional regulator"
                     /protein_id="HFG9699579.1"
                     /translation="MKKSVALVNDSRKDLIDFLENNLKLVFGDSININRYFINEINDN
                     DIINDDVILVMSVERLDKIINNILDKKKVIVVRRTFREDKIYNLLSLPQGTNVLIVND
                     SDETTLETISLFYKIGVTNIRPIPYMNDNNYKNIKIAITPGVPEKVPSFISDIFDLGH
                     RYIDISTFIEIINLLQIDSKEIQSNLVKYSEEIISLDTGIKDKYKELFLKIEELDTIL
                     NLSKDGILFTSKDGEINTYNSKVKDILDINEDIYGKYIEDIFVDSLKVLLSEKEILDK
                     VVVFNKKYINVNKKNIYNRDEKMGTYYSLQEITYIKKLEQNLTKKLREKGQIAKYTFK
                     DIKTNSPKMFECIDLAKKVSKSDLSILIRGESGTGKELIAQSIHNNSNRKNQPFIAVN
                     CAAVPENLLESQLFGYDKGTFTGGLKDGKQGLFELANNGTIFLDEIGDMPLELQTKLL
                     RVLQEKQIMPVGSHNVINIDVRIISATNKNLEQMIDNSQFREDLYYRLNTIPINIPPL
                     RERKEDILIIMEDLINKKLVITPEAKKLIQNYMWKGNIRELQNVTSYLNIMCEDIVLE
                     KDLPPNLRSSDNKNTSLKLKYSKNDILNILEILILNKESDVGIGRGLILKALLDKNLQ
                     ITEGKIKKIFEYLKKEELIICSSGRYGSKITQKGEDFYNKLKYKGL"
BASE COUNT         1031 a          225 c          334 g          723 t
ORIGIN      
        1 aatgaaaaat atacatacag tttaagtttt aagcaacaat tagggggatt tggtgacaag
       61 atttttaatt ataagaaaga aagtgtctta atgcaacttt tataaagtca ttatagacac
      121 tttctttttt atttgataaa tttaaattat caaaattata ttgctttata caactatttt
      181 gttggaaact atttattata taaggagaaa taaatgaaaa aatcagtagc tctggtaaat
      241 gatagtagaa aagatttaat agacttttta gaaaataatt tgaaattagt ttttggagat
      301 tctataaata ttaatagata cttcataaat gaaataaatg ataatgatat tataaatgat
      361 gatgtgatat tagtaatgtc agtagaaaga ttagacaaaa ttataaataa tatactagat
      421 aagaaaaaag tgattgtggt aagaagaact tttagggaag ataaaattta taatctacta
      481 tctttaccac agggtacaaa tgttctaatc gtaaatgatt ctgatgaaac tactctagaa
      541 actataagtt tattttataa aattggagtg actaatatta gaccaattcc atatatgaat
      601 gataataact ataaaaatat aaaaatagct ataactccag gagttccaga aaaagtacct
      661 agctttatct cagatatatt tgatttaggt cacagatata tagatatttc tacatttata
      721 gaaataataa atttattaca aattgattca aaggaaatac aatctaatct agttaaatac
      781 tcagaagaaa taataagttt agatactggt ataaaagata aatataagga attattttta
      841 aaaatagaag aattagatac aatattgaat ttatcaaaag atggtatatt atttacttca
      901 aaagatggtg aaataaatac atataatagt aaagtaaaag atattttaga cataaatgag
      961 gatatatatg gaaaatacat tgaggatata tttgtagata gtttaaaagt tttattgagt
     1021 gagaaagaga tactagataa agttgtcgta ttcaataaga aatatataaa tgtaaataaa
     1081 aaaaacatat acaatagaga tgaaaaaatg ggcacatatt atagtttaca agaaataaca
     1141 tacataaaaa aattagaaca aaatctcact aaaaaattaa gagaaaaagg acaaatagca
     1201 aaatatacat ttaaggatat aaaaacaaat agtcctaaaa tgtttgaatg tatagattta
     1261 gctaagaagg tttctaaatc tgacttaagc atacttatca gaggtgaaag tggaactggt
     1321 aaagaactca tagctcagtc tatacataac aactcaaata gaaaaaatca accctttata
     1381 gcagtaaatt gtgcagccgt tcctgaaaat ttattagaaa gccagctatt cggatatgac
     1441 aagggaactt ttactggagg tctaaaagat ggaaaacaag gattatttga acttgctaat
     1501 aatggaacaa tattcttaga tgaaataggc gatatgcctt tagaattaca aacaaaacta
     1561 cttagagttc ttcaagaaaa gcagataatg cctgttgggt ctcacaatgt aattaatata
     1621 gatgttagaa tcatatctgc tacaaataag aatttagaac aaatgattga taatagccaa
     1681 tttagagagg atttatatta tcgattaaat acaattccaa taaatatacc tcctctaaga
     1741 gaaagaaaag aagacatatt aattattatg gaagatttaa ttaataagaa attagtaatc
     1801 acaccagaag caaaaaaact tatacaaaac tatatgtgga aaggtaatat aagagaactc
     1861 caaaatgtta catcctattt aaacattatg tgtgaagata ttgtattaga gaaagattta
     1921 cctccaaact taaggtcttc agataacaaa aatacatcat taaaactaaa atatagtaag
     1981 aatgatatat tgaatatatt agagatacta attttaaata aggaatcaga tgttggtatt
     2041 ggtagaggat taattttaaa agcactactc gataagaacc ttcaaattac agaaggaaaa
     2101 attaaaaaaa tatttgaata tctaaaaaaa gaagaactta taatttgtag ttcaggaaga
     2161 tatggaagta aaataactca aaaaggagaa gatttttaca ataaattaaa atataaaggt
     2221 ctataaaatt ataatttatc aaacaaagaa atctattcag gattaaagta ctccttcaat
     2281 aggttttttt atttttcaag taccctgaaa tta
//
LOCUS       DAYAOO010000192         2237 bp    DNA     linear   BCT 12-OCT-2024
DEFINITION  TPA_asm: Clostridioides difficile isolate ST8-SSI-h139-18
            SAMN40601845-rid21577343.denovo.196, whole genome shotgun sequence.
ACCESSION   DAYAOO010000192 DAYAOO010000000
VERSION     DAYAOO010000192.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN40601845
            Sequence Read Archive: SRR28438827
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 2237)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2237)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-MAY-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-MAY-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002157583.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002157583.1
            Genome Coverage       :: 163x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/11/2024 16:19:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 4,038
            CDSs (total)                      :: 3,963
            Genes (coding)                    :: 3,930
            CDSs (with protein)               :: 3,930
            Genes (RNA)                       :: 75
            rRNAs                             :: 6, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 60
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 33
            CDSs (without protein)            :: 33
            Pseudo Genes (ambiguous residues) :: 0 of 33
            Pseudo Genes (frameshifted)       :: 7 of 33
            Pseudo Genes (incomplete)         :: 25 of 33
            Pseudo Genes (internal stop)      :: 11 of 33
            Pseudo Genes (multiple problems)  :: 8 of 33
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2237
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN40601845-rid21577343.denovo.196"
                     /isolate="ST8-SSI-h139-18"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Denmark"
                     /collection_date="2018"
                     /collected_by="Statens Serum Institute"
     gene            103..1317
                     /gene="dpaL"
                     /locus_tag="ACGI5H_003909"
     CDS             103..1317
                     /gene="dpaL"
                     /locus_tag="ACGI5H_003909"
                     /EC_number="4.3.1.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004453094.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008838 - diaminopropionate ammonia-lyase
                     activity [Evidence IEA];
                     GO_function: GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="diaminopropionate ammonia-lyase"
                     /protein_id="HFG9699580.1"
                     /translation="MREIKWKLNNLPKSEEKEKGIEFLKDEEIAKAKAFHESFPQYEK
                     TPLVKLDNLAKSLGVSGIYVKDESYRFGLNAFKVLGGSYSMGRYLAQRLDTDISELGY
                     DKLTSKEIKEKLGEITFFTATDGNHGRGVAWTANKLGQKSVVLMPKGSSEFRLNKIKG
                     EGADASITDLNYDDAVRLANDYAEADDHGVMVQDTAWDGYEEIPAWIMQGYGTMAKEA
                     IEQLKEYGVDRPTHVFVQAGVGSLAGAVQGYVASIYDECPITVVVEADEADCYYKSAE
                     AGDGKPRFVGGDMPTIMAGLACGEPNTIGFEVLKNYSSAFVSAPDWVSAKGMRILGNP
                     LRGDEKVISGESGAVTTGALVSILESEDLKDLREALKLDENSKVLLISTEGDTDPDKY
                     RDIVWNGECQSK"
     gene            1647..>2237
                     /locus_tag="ACGI5H_003910"
     CDS             1647..>2237
                     /locus_tag="ACGI5H_003910"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893427.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="M20/M25/M40 family metallo-hydrolase"
                     /protein_id="HFG9699581.1"
                     /translation="MLNETRKKQLTEVCQDLIRNASYSGQEENVVKAIEENFALLGFD
                     SWSRDRYGNIVGCIKGNKPGKKILFDGHIDTVPVPDASKWSVPPFEARIVDGKIYGRG
                     TSDMKGQVSAMMAAVSYFAEDTNKDFEGELYVAGVVHEEIFEGVSAREISKAVQPDYV
                     VIGESSELNLKIGQRGRGEIVVETFGKPAHSANPEKG"
BASE COUNT          956 a          242 c          449 g          590 t
ORIGIN      
        1 ttttagaata aataatattg gcacggtaat tgctttgcta taaggcacaa agataaaaaa
       61 ttaaaatgac accgaaaaat ttgaaagggg aatataaaat aaatgagaga aataaaatgg
      121 aaattaaata acttacctaa atcagaggaa aaagaaaaag gaattgaatt tttaaaagat
      181 gaagagattg caaaggctaa agcttttcat gaaagctttc cacaatatga aaaaactcct
      241 ttagttaaat tagataactt agcaaaatca ctaggcgtaa gcggaatata tgttaaagac
      301 gaatcttata gatttggttt aaacgcattt aaagttttag gtggttctta ctctatgggt
      361 agatacttag ctcaaagatt agatacagat atatctgagt tagggtatga taaattaact
      421 tcaaaagaaa taaaagaaaa attaggagaa ataactttct ttacagctac agatggaaat
      481 catggtagag gagttgcttg gacagctaat aaattaggtc aaaaatctgt tgtattaatg
      541 ccaaaaggtt cttctgaatt tagattaaat aaaatcaaag gagaaggtgc agatgctagt
      601 ataacagact taaactatga tgatgcagta agattagcta atgattatgc agaagctgat
      661 gaccatggag taatggttca agatacagca tgggacggat atgaagaaat accagcatgg
      721 ataatgcaag gatatggaac tatggctaaa gaagctatag aacaattaaa agaatatgga
      781 gtagatagac caacacacgt atttgttcaa gcaggagttg gttcacttgc tggtgcagtt
      841 caaggatatg ttgcttcaat atatgatgaa tgcccaataa cagtagtagt agaggctgat
      901 gaggctgact gttactataa atcagcagaa gctggagatg gaaaaccaag atttgttgga
      961 ggagatatgc caactataat ggcagggctt gcttgtggag aaccaaacac tataggtttt
     1021 gaagtgttaa aaaattattc atcagcattc gtttcagcac cagactgggt atctgctaaa
     1081 ggtatgagaa tattaggaaa ccctctaaga ggagatgaga aagtaatctc tggagaatct
     1141 ggagcagtta caactggagc attagtttca atccttgaaa gtgaagattt aaaagactta
     1201 agagaagctt tgaaactaga tgagaactct aaagtattat taataagtac agaaggagat
     1261 actgaccctg ataaatatag agatatagtt tggaatggtg aatgccaaag taaataaaag
     1321 acttaaggaa aagaaaatct taacaaataa atgaaaaatt taaggaaaat aaaaacttaa
     1381 ataagtgaaa actttaaata aaataaaaac taaaacaaat gaaaaatcta aataaatgaa
     1441 aaagtaaagc aaataaaaaa gtaaagcaaa tgaaaaattc aaaataaaaa ccaaataaaa
     1501 ttaaaataaa gtctaaataa aaatttaata aataaaatat aaagaaataa aaaatcaata
     1561 gattaagtga aatgctaata aattaaaaaa atgaaatatc aaaataaaac gtcaacaaat
     1621 taaaaattat atgggggaat atcaaaatgt taaatgaaac aagaaaaaaa caattaactg
     1681 aagtatgcca agacttaata agaaatgcta gttattcagg tcaagaagaa aacgtagtaa
     1741 aagctataga agaaaatttt gctttactag gttttgatag ttggtcaaga gatagatatg
     1801 gaaatatagt aggatgtata aaaggaaata aaccaggtaa aaaaatatta tttgacgggc
     1861 atatagatac agttccagtt ccagatgcaa gtaaatggag tgttcctcct tttgaagcga
     1921 gaatagtaga tgggaaaata tatggtagag gaacttctga tatgaagggg caagtaagtg
     1981 ctatgatggc tgctgtttca tactttgcag aagatactaa caaagacttt gaaggtgaat
     2041 tgtatgtagc aggtgttgtt catgaagaaa tatttgaagg tgtttcagct agagagataa
     2101 gtaaggctgt tcaacctgat tatgttgtaa taggtgaatc ttcagaatta aacctaaaga
     2161 taggtcaaag aggtagagga gaaatagtag tagaaacttt tggtaaacca gctcactctg
     2221 ctaatccaga aaaaggt
//
LOCUS       DAYAOO010000193         1865 bp    DNA     linear   BCT 12-OCT-2024
DEFINITION  TPA_asm: Clostridioides difficile isolate ST8-SSI-h139-18
            SAMN40601845-rid21577343.denovo.197, whole genome shotgun sequence.
ACCESSION   DAYAOO010000193 DAYAOO010000000
VERSION     DAYAOO010000193.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN40601845
            Sequence Read Archive: SRR28438827
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 1865)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1865)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-MAY-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-MAY-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002157583.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002157583.1
            Genome Coverage       :: 163x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/11/2024 16:19:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 4,038
            CDSs (total)                      :: 3,963
            Genes (coding)                    :: 3,930
            CDSs (with protein)               :: 3,930
            Genes (RNA)                       :: 75
            rRNAs                             :: 6, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 60
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 33
            CDSs (without protein)            :: 33
            Pseudo Genes (ambiguous residues) :: 0 of 33
            Pseudo Genes (frameshifted)       :: 7 of 33
            Pseudo Genes (incomplete)         :: 25 of 33
            Pseudo Genes (internal stop)      :: 11 of 33
            Pseudo Genes (multiple problems)  :: 8 of 33
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1865
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN40601845-rid21577343.denovo.197"
                     /isolate="ST8-SSI-h139-18"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Denmark"
                     /collection_date="2018"
                     /collected_by="Statens Serum Institute"
     gene            21..1160
                     /locus_tag="ACGI5H_003911"
     CDS             21..1160
                     /locus_tag="ACGI5H_003911"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728737.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fic family protein"
                     /protein_id="HFG9699582.1"
                     /translation="MVIKLTIEEYKNKYFTGNKIVLSINSFDNKELYYHETENILNLI
                     NEIDKLTSSKIFKTIEDKNDLALESYYSSVIEGAFSTRKIAKSIIRGKMKPSNKSEYM
                     IYNNHRALEYGLDNLDELYSHKFIYDLHHILGENCLDSEEYEYRTEKVYVCDSKGEII
                     HTGLEPLKIYDFISKLIDFMENSKVSNLIKSAIIHFYFVYVHPFSDGNGRTSRALSYL
                     YLIDKGYDTFKDFSISYMISKNRTKYYKAILDVENKGNNLTVFIEFMLKSIIQSINEM
                     RNMHDRKSLESILKEELFENDITLSATEEHILKYICNKDNYSMTLENYIKKNKSRYLK
                     AGIKEIELVDQLMEVFNNLEEIEILSKEKNIYKVNDKYLKMLDID"
     gene            1186..1374
                     /locus_tag="ACGI5H_003912"
     CDS             1186..1374
                     /locus_tag="ACGI5H_003912"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426367.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9699583.1"
                     /translation="MNNKKKAFLISGAINVISLIIVFSLFHYNIIENSTQNMIITVIL
                     IFIFEMIKIKIIEKYYKL"
BASE COUNT          797 a          150 c          273 g          645 t
ORIGIN      
        1 atagataaag ataatctaag gtggtgatta aactgacaat agaagaatac aaaaacaaat
       61 actttactgg aaataaaatc gtactttcta taaatagttt tgataataaa gaactatact
      121 atcatgaaac tgaaaatata ttaaatttaa taaatgaaat agataaatta acatcaagta
      181 agatatttaa aacaatagaa gataaaaatg atttggcact agagtcttat tattctagtg
      241 taatagaagg tgctttttca actagaaaga ttgcaaaatc tataattaga ggaaagatga
      301 aaccaagtaa taaaagtgaa tatatgattt acaataatca tagagcctta gaatatggat
      361 tagataactt agatgaattg tatagtcaca aatttatata tgatttgcat catatattgg
      421 gcgaaaactg cttggattca gaagaatatg agtatagaac tgaaaaagta tatgtatgtg
      481 attcaaaagg tgagattata catacagggc ttgaaccttt gaagatatat gactttatta
      541 gtaaattaat agattttatg gaaaatagca aagtaagtaa tttaattaaa agtgctataa
      601 ttcattttta ctttgtatat gttcatcctt ttagtgatgg taatggaaga acatcaagag
      661 ccttatcata tctatatttg attgataaag gatatgatac tttcaaggat ttttcaatat
      721 catatatgat atctaaaaac agaactaagt attataaggc tatacttgat gtagaaaaca
      781 aaggaaataa tttaactgta tttatagaat ttatgctcaa gtctataata caatctatta
      841 atgagatgcg taatatgcat gatagaaaat ctttagaaag tatattaaaa gaagaattgt
      901 ttgaaaatga cataactcta tcagcaacag aagaacatat attaaaatat atttgcaata
      961 aagataacta ttctatgaca ttagaaaatt atataaaaaa gaataaaagt agatacttaa
     1021 aggctggaat aaaggaaatt gaattagttg accagttgat ggaagtgttt aataatcttg
     1081 aagagataga gattttgtct aaagaaaaaa atatatataa agttaatgat aagtacttaa
     1141 aaatgcttga tatagactaa tttagataat ctggagaggg aatatatgaa taataagaaa
     1201 aaggcatttt tgatttctgg ggctataaac gtaatttcat taattattgt tttttcattg
     1261 tttcattata atattataga aaatagtaca caaaatatga taataactgt aatcttaatt
     1321 tttatttttg aaatgataaa aataaaaatc atagagaaat actataaact ataaacaaga
     1381 aatatctttt ctaagagcat attgtacaat atgctcttaa tttagttata tagatttaat
     1441 ataaataatg tattttttgt agatgattta tgtaagattt atgaccaatt tgtgtatgat
     1501 ttgtgttctt taatcatgac aatattatat tgtaaaaaat aaatttaata aaaaatgact
     1561 tggaatttat attctaggtc ttttttatat aaaaatttaa taagtttcaa atgttggtaa
     1621 ctttgacagt agaaaacgtc tattgagata acgaggattc taattgaggt ggagagatat
     1681 tagcacttaa agtagtatat gcaacagata taatctttac aaaagtaatt tgaattaaaa
     1741 tgtaaatata aagaataatt aaaaaaatat cgcaattatt tgtttttcat atggataaaa
     1801 ttggttattt aatatataat tacaagtata aataataaaa tttatttgta aaaagagtag
     1861 cactt
//
LOCUS       DAYAOO010000194         1713 bp    DNA     linear   BCT 12-OCT-2024
DEFINITION  TPA_asm: Clostridioides difficile isolate ST8-SSI-h139-18
            SAMN40601845-rid21577343.denovo.198, whole genome shotgun sequence.
ACCESSION   DAYAOO010000194 DAYAOO010000000
VERSION     DAYAOO010000194.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN40601845
            Sequence Read Archive: SRR28438827
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 1713)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1713)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-MAY-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-MAY-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002157583.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002157583.1
            Genome Coverage       :: 163x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/11/2024 16:19:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 4,038
            CDSs (total)                      :: 3,963
            Genes (coding)                    :: 3,930
            CDSs (with protein)               :: 3,930
            Genes (RNA)                       :: 75
            rRNAs                             :: 6, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 60
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 33
            CDSs (without protein)            :: 33
            Pseudo Genes (ambiguous residues) :: 0 of 33
            Pseudo Genes (frameshifted)       :: 7 of 33
            Pseudo Genes (incomplete)         :: 25 of 33
            Pseudo Genes (internal stop)      :: 11 of 33
            Pseudo Genes (multiple problems)  :: 8 of 33
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1713
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN40601845-rid21577343.denovo.198"
                     /isolate="ST8-SSI-h139-18"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Denmark"
                     /collection_date="2018"
                     /collected_by="Statens Serum Institute"
     gene            complement(<1..236)
                     /locus_tag="ACGI5H_003913"
     CDS             complement(<1..236)
                     /locus_tag="ACGI5H_003913"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728849.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9699584.1"
                     /translation="MTFKELVNKVRNLVLEAKNVTIEDTENNFTSDNVEGALKEVFQS
                     GVNAKNNVVTALNSKGAEVTTNNTWEEIKNKVNN"
     gene            complement(271..453)
                     /locus_tag="ACGI5H_003914"
     CDS             complement(271..453)
                     /locus_tag="ACGI5H_003914"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426811.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9699585.1"
                     /translation="MSINNVVVRILAERILNKGLNPLKNREFELDDVTNIEYRKAVED
                     YIIKESGVVEGAETTI"
     gene            complement(453..746)
                     /locus_tag="ACGI5H_003915"
     CDS             complement(453..746)
                     /locus_tag="ACGI5H_003915"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861044.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9699586.1"
                     /translation="MNRANRIIYDQTGKILLQTGEATGDVLEHDEITELHCIDVPYGS
                     IDYTKNRITGINIETKEPILEEIPIFVTEEEKRIQELENQILLNENEKVGGLL"
     gene            complement(760..>1713)
                     /locus_tag="ACGI5H_003916"
     CDS             complement(760..>1713)
                     /locus_tag="ACGI5H_003916"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009901440.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9699587.1"
                     /translation="LITLLQALPFLTVSSYNSTQATFKADHTDPTLLTKIEVFIDDVL
                     KETITTDLTTEKTINYTLEDNALHTLKIVVTDSNNATAEKVLSISKNIMPLPENVNLN
                     DISTKLVEVNAGFKVGKTSIINTLALKNIEASLNNTLVELSEKIKTSFDSGDASLQDL
                     MNQLTQANNTISQLNSKYKVASGTTTVIQSSKRVNLYGGLYGQTYIREPYHWININNL
                     GFIPNIFIAENETVSAGSSIQKNIIIATCNIPWSTNKRDFIANLQLTRGKMDDQDFNC
                     HAGFYINNEQDAYINSNGINVPASRASLPIYGFSWYAIKFI"
BASE COUNT          493 a          301 c          202 g          717 t
ORIGIN      
        1 ttgttgttta ctttattctt tatttcctcc caagtgttat ttgtagtaac ctctgcaccc
       61 ttggagttca atgctgttac tacattattt ttagcattaa ctccactttg aaaaacctct
      121 tttaatgctc cctcaacatt atcacttgta aagttattct ctgtatcttc tatagttaca
      181 ttttttgctt ctagtacaag atttctaact ttattaacta actctttaaa agtcatttaa
      241 tcaccttctt tcaataaaaa aaagaaccct ctatatagtt gtttctgctc cttctactac
      301 tccgctttct ttaattatat aatcctctac tgcctttcta tactctatgt tagtcacgtc
      361 atctaattca aattctcgat ttttcaaagg atttaaccct ttatttaata ttctctctgc
      421 taatattctt actacaacat tatttatact cattataata atcctcctac tttctcattt
      481 tcatttaata aaatttgatt ttctaactct tgtattctct tttcttcttc tgtaacgaat
      541 attggtattt cttccaaaat tggttctttt gtttctatat ttatgcctgt aattctattt
      601 ttggtatagt ctatacttcc atatggaaca tcaatgcaat gtaattctgt tatttcatca
      661 tgttccaaga catcccctgt cgcctctcct gtttggagta atattttacc agtttggtca
      721 taaattattc tatttgctct attcatttta tcacctcatt tatataaatt ttatagcata
      781 ccaagaaaac ccataaatag gaagagaagc tctacttgca ggtacattaa ttccattact
      841 attaatataa gcatcttgct cattgtttat ataaaatcct gcatgacaat taaaatcttg
      901 gtcatccatt ttacctctag taagttgtaa gtttgctata aaatctcttt tatttgtaga
      961 ccaaggtata ttgcaagtag caataataat atttttttgg attgaactac cagcactaac
     1021 agtttcattt tcagcgataa aaatattagg aataaatcct aaattattaa tattaatcca
     1081 atgatatggt tctctaatat atgtttgtcc atataaccca ccatatagat taacacgctt
     1141 agaactttga ataacagtgg tagtgccact tgcgacttta tatttagagt ttaattgcga
     1201 tatagtatta ttagcttgtg ttaactgatt catcaaatcc tgcaaacttg catctccact
     1261 gtcaaaagaa gttttaattt tctctgataa ctccactaat gtattattta aacttgcctc
     1321 tatattcttt aatgctaaag tatttataat gcttgttttc ccaactttaa atcctgcatt
     1381 aacctcaact aattttgttg atatatcatt taaatttaca ttttcgggca gtggcattat
     1441 attcttactt atacttaaaa ctttttcagc agttgcatta ttgctgtctg taacaactat
     1501 tttaagcgtg tgcagtgcat tatcttctaa tgtatagtta attgttttct ctgttgttaa
     1561 atctgttgtt atagtttctt ttagtacatc atctataaat acttctatct tagttaatag
     1621 tgtagggtct gtgtggtcag ctttaaatgt tgcttgtgtg gagttataag aggatacggt
     1681 taaaaaaggt aatgcttgta gtaatgttat tag
//
LOCUS       DAYAOO010000195         1677 bp    DNA     linear   BCT 12-OCT-2024
DEFINITION  TPA_asm: Clostridioides difficile isolate ST8-SSI-h139-18
            SAMN40601845-rid21577343.denovo.199, whole genome shotgun sequence.
ACCESSION   DAYAOO010000195 DAYAOO010000000
VERSION     DAYAOO010000195.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN40601845
            Sequence Read Archive: SRR28438827
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 1677)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1677)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-MAY-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-MAY-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002157583.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002157583.1
            Genome Coverage       :: 163x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/11/2024 16:19:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 4,038
            CDSs (total)                      :: 3,963
            Genes (coding)                    :: 3,930
            CDSs (with protein)               :: 3,930
            Genes (RNA)                       :: 75
            rRNAs                             :: 6, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 60
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 33
            CDSs (without protein)            :: 33
            Pseudo Genes (ambiguous residues) :: 0 of 33
            Pseudo Genes (frameshifted)       :: 7 of 33
            Pseudo Genes (incomplete)         :: 25 of 33
            Pseudo Genes (internal stop)      :: 11 of 33
            Pseudo Genes (multiple problems)  :: 8 of 33
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1677
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN40601845-rid21577343.denovo.199"
                     /isolate="ST8-SSI-h139-18"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Denmark"
                     /collection_date="2018"
                     /collected_by="Statens Serum Institute"
     gene            42..1640
                     /locus_tag="ACGI5H_003917"
     CDS             42..1640
                     /locus_tag="ACGI5H_003917"
                     /EC_number="3.6.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427831.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative manganese-dependent inorganic
                     diphosphatase"
                     /protein_id="HFG9699588.1"
                     /translation="MSLLVFGHKNPDTDSICSAISLAHLKNKLGIKATAYALGDIRKE
                     AKYALDYFKVDAPEILDNVRIQVRDLNYDKVVPLTPTSSILEAYNLMDEKNVKTLPVT
                     YDDGTFAGIITMKEIAKNLLHQHFTTIHTSLSNICKNLNGTILVDCGEDIKGRVVTLS
                     FGMETLIETLKEGDIAIVGDRYDSIEYAIDTKVKLLILTNHTEISKDLLALAKINGVS
                     VVSVESDNYKTSNVINQCSFLDSIEATENLITFKEDDYMDEIKEIMLETNFRSYPILD
                     DDNKFLGLVSKGHLLNPSKKNVVLVDHNEYAQSADGIEQANIVEIIDHHKLGGISTDV
                     PMSFRVMPVGCNSTIIYQMYKENNVEIPYEIAGLLLSAILSDTLLFKSPTTTDIDKKA
                     CEELSKIAKVDMEKYAMDMFKCGTSLDEYTIEEIVNMDFKEFNMSGHRVGIGQVFTLD
                     IDSIFAKKDEFLSYINSTDYDKLILAVTDIIKEGSYLIYKAEDSLIANAFGVEGVQGT
                     FAPGVVSRKKQLVPNLTTAIKNFK"
BASE COUNT          646 a          210 c          270 g          551 t
ORIGIN      
        1 atcaattatt attatattca agttttgaaa ggagtattaa aatgagttta ttagttttcg
       61 gacataaaaa tccagataca gattcaatat gttctgcaat ttcattagca catttaaaga
      121 acaaactagg aataaaagca acagcttatg ctttaggaga tatcagaaaa gaagctaaat
      181 atgccttgga ttactttaag gtagatgcac ctgaaatttt agataatgtt agaatacaag
      241 ttagagattt aaattatgat aaagtagtac ctttaacacc aacttcatct atattagagg
      301 cttataacct tatggatgaa aaaaatgtta aaacactacc tgtaacttat gatgatggaa
      361 cttttgctgg tatcattact atgaaagaaa tagctaaaaa tctacttcat caacacttta
      421 caactataca cacatcacta tcaaacattt gtaaaaacct taatggtact attcttgtgg
      481 actgtggtga agatataaaa ggtagagtag tcactttatc atttggaatg gagactctaa
      541 tagagacttt aaaagaagga gacatagcta ttgttggaga tagatatgat agtattgaat
      601 atgctattga tacaaaagtt aaacttttaa tacttactaa tcatacagag atttcaaaag
      661 atttgctagc tcttgctaag ataaatggag tgtctgttgt ttctgttgaa agtgacaatt
      721 ataaaacttc taatgtaata aatcaatgta gtttcttaga ctctatagaa gctacagaaa
      781 atttaattac attcaaagaa gatgattata tggatgaaat aaaagagatt atgctagaaa
      841 caaacttcag atcttatcca atattagatg atgataataa gtttttaggt ttagtttcaa
      901 aaggtcatct attaaaccca tctaaaaaga atgttgtttt agttgaccat aacgaatatg
      961 ctcaaagtgc tgatggaatt gaacaagcaa acatagttga aataattgac catcataaac
     1021 ttggtggtat ttctactgat gttcctatgt catttagagt tatgcctgtt ggatgcaata
     1081 gtactataat ttatcaaatg tacaaagaaa ataatgttga gataccttat gaaatagccg
     1141 ggcttctttt atctgctata ttatcagata cattattatt taagtctcca acaacaactg
     1201 atatagataa gaaagcttgt gaagaattaa gtaaaatagc aaaagtagac atggaaaaat
     1261 acgctatgga tatgtttaaa tgcggtactt ctttagatga atatactata gaagaaatag
     1321 taaatatgga ctttaaagaa tttaatatga gtggacatag agttggtatt ggacaagtat
     1381 ttaccttaga catagactct atatttgcta aaaaagatga gtttttatct tatataaatt
     1441 cgactgatta tgacaaacta attcttgcgg ttacagatat aatcaaagaa ggttcttatt
     1501 taatctataa agcagaagac agcttaattg ctaacgcatt tggtgttgaa ggtgttcaag
     1561 gtacatttgc accaggtgtt gtatcaagaa aaaaacaatt agtccctaat ttaactactg
     1621 caatcaaaaa ttttaaataa tataaaattt ttaaataacg aaaactgtct caaatct
//
LOCUS       DAYAOO010000196         1652 bp    DNA     linear   BCT 12-OCT-2024
DEFINITION  TPA_asm: Clostridioides difficile isolate ST8-SSI-h139-18
            SAMN40601845-rid21577343.denovo.200, whole genome shotgun sequence.
ACCESSION   DAYAOO010000196 DAYAOO010000000
VERSION     DAYAOO010000196.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN40601845
            Sequence Read Archive: SRR28438827
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 1652)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1652)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-MAY-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-MAY-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002157583.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002157583.1
            Genome Coverage       :: 163x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/11/2024 16:19:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 4,038
            CDSs (total)                      :: 3,963
            Genes (coding)                    :: 3,930
            CDSs (with protein)               :: 3,930
            Genes (RNA)                       :: 75
            rRNAs                             :: 6, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 60
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 33
            CDSs (without protein)            :: 33
            Pseudo Genes (ambiguous residues) :: 0 of 33
            Pseudo Genes (frameshifted)       :: 7 of 33
            Pseudo Genes (incomplete)         :: 25 of 33
            Pseudo Genes (internal stop)      :: 11 of 33
            Pseudo Genes (multiple problems)  :: 8 of 33
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1652
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN40601845-rid21577343.denovo.200"
                     /isolate="ST8-SSI-h139-18"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Denmark"
                     /collection_date="2018"
                     /collected_by="Statens Serum Institute"
     gene            118..1554
                     /locus_tag="ACGI5H_003918"
     CDS             118..1554
                     /locus_tag="ACGI5H_003918"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897130.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall-binding protein Cwp28"
                     /protein_id="HFG9699589.1"
                     /translation="MKFYKRILTLTLSISFVFANIQLVDAISSVEKIQGKNKYEIAGK
                     IADKNAYKTAILINTSNSIADGLSASGLAGALNAPILLTEKNTIPTETSARLKNVSKV
                     YIIGGTYSISTSVENSLKSKKMKVVRIKGNDRIKTSYNVAKEINSIKKVNTVMLTNAY
                     KGEADAISIASVAARDKAPIILTNGQSIPFSTSGLKSYVIGGTASMSTTLVNNTKSTR
                     LGGSTRFETNKAIINKFYKDAREFYIAGAYELTNALVGSSLSKHGPMVLVNDGSNKSI
                     LKNAKKITSIGYIDSNIVQQCLNITNGIGDINTGVVKNVKPTTKTIKDGMYKVGKDIS
                     AGEYLITSNSGSYASYYEVTSDSTGNADSILSNDIFSGTRYITLKNGQYIKIEDSTMT
                     LAKYAKAQKAKNGKFGNGMYKIGLEIPAGEYIIMSNSSDAYYEVRNDSLGNAEGIVTN
                     DTFSGRRYITVEEGQYLILNDCYLIENE"
BASE COUNT          671 a          167 c          277 g          537 t
ORIGIN      
        1 ttatttgtaa tatgcttaat ataatttgca attttacata agtttgttaa gtacataact
       61 aatttaagaa tatgtattta tatattaaaa atttattatg agggggacaa ttttattatg
      121 aaattctata aaagaatatt aacattgact ttaagtattt cttttgtatt tgcaaatatt
      181 caattagtag atgcaatatc atctgtagaa aaaatacaag gaaaaaataa gtatgaaatc
      241 gcaggtaaaa tagcagataa aaatgcatat aaaactgcta tattaattaa tactagtaac
      301 tctattgcag atggattaag tgcaagtgga ctagcaggag ctttaaatgc ccctatacta
      361 ttaactgaaa aaaatactat accaactgag acatctgcaa gattaaaaaa tgtatcaaaa
      421 gtttatataa ttggaggaac atattctatt agtacatctg tcgaaaattc attaaaatct
      481 aagaaaatga aagttgtaag aattaaggga aatgacagaa taaaaacaag ttataatgtt
      541 gcaaaagaaa taaattcaat aaaaaaagtc aatactgtta tgctaaccaa tgcatataaa
      601 ggagaagcag atgctataag tattgcatct gtagcagcaa gagataaagc accaataatt
      661 cttactaatg gacaaagtat acctttttca actagtggtt taaagtctta tgtaatagga
      721 ggaacagctt caatgagtac cactttagta aacaatacta aatctactag actagggggg
      781 agtactcgtt ttgaaactaa taaagcaata ataaataagt tttataagga tgctagagag
      841 ttttatatag ctggagctta tgaattaaca aatgcacttg taggatcttc tttatcaaaa
      901 catggtccaa tggttttagt taatgatggt agcaataaaa gcattttaaa aaatgctaag
      961 aagataactt ctataggata tatagattca aatatagtac aacagtgttt aaatataaca
     1021 aatggaattg gagatattaa tactggggtt gtaaaaaatg ttaaacctac tacaaagact
     1081 ataaaagatg gaatgtataa ggttggaaaa gatatctcag caggtgaata cttaataact
     1141 tcaaactcag gaagttatgc ttcttattat gaagttacaa gtgatagtac aggtaatgct
     1201 gatagtatac tttcaaatga tatttttagt gggactagat atatcacctt aaagaatggt
     1261 caatatatta aaattgagga ttcaacaatg acattagcaa agtatgctaa agcccagaag
     1321 gccaagaatg gtaagtttgg aaatggtatg tataaaattg gattagaaat tcctgctgga
     1381 gaatatatta taatgtcaaa ttcttctgat gcatattatg aagttagaaa tgatagctta
     1441 ggtaatgcag agggaatagt tactaatgat actttttcag gaagaagata tataacggtt
     1501 gaggaaggtc aatatttaat attaaatgat tgttatttaa ttgaaaatga atagatgtaa
     1561 ttgtatttaa tagtaaatca tatattttat ttaaggaaag gtgttttaag ttttaattta
     1621 aaacatcttt ttattattat aataattata tg
//
LOCUS       DAYAOO010000197         1608 bp    DNA     linear   BCT 12-OCT-2024
DEFINITION  TPA_asm: Clostridioides difficile isolate ST8-SSI-h139-18
            SAMN40601845-rid21577343.denovo.201, whole genome shotgun sequence.
ACCESSION   DAYAOO010000197 DAYAOO010000000
VERSION     DAYAOO010000197.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN40601845
            Sequence Read Archive: SRR28438827
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 1608)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1608)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-MAY-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-MAY-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002157583.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002157583.1
            Genome Coverage       :: 163x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/11/2024 16:19:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 4,038
            CDSs (total)                      :: 3,963
            Genes (coding)                    :: 3,930
            CDSs (with protein)               :: 3,930
            Genes (RNA)                       :: 75
            rRNAs                             :: 6, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 60
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 33
            CDSs (without protein)            :: 33
            Pseudo Genes (ambiguous residues) :: 0 of 33
            Pseudo Genes (frameshifted)       :: 7 of 33
            Pseudo Genes (incomplete)         :: 25 of 33
            Pseudo Genes (internal stop)      :: 11 of 33
            Pseudo Genes (multiple problems)  :: 8 of 33
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1608
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN40601845-rid21577343.denovo.201"
                     /isolate="ST8-SSI-h139-18"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Denmark"
                     /collection_date="2018"
                     /collected_by="Statens Serum Institute"
     gene            94..1530
                     /gene="miaB"
                     /locus_tag="ACGI5H_003919"
     CDS             94..1530
                     /gene="miaB"
                     /locus_tag="ACGI5H_003919"
                     /EC_number="2.8.4.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428816.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016782 - transferase activity,
                     transferring sulphur-containing groups [Evidence IEA];
                     GO_function: GO:0051539 - 4 iron, 4 sulfur cluster binding
                     [Evidence IEA];
                     GO_function: GO:1904047 - S-adenosyl-L-methionine binding
                     [Evidence IEA];
                     GO_process: GO:0006400 - tRNA modification [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (N6-isopentenyl
                     adenosine(37)-C2)-methylthiotransferase MiaB"
                     /protein_id="HFG9699590.1"
                     /translation="MSKRKQVTIPIEKIQEQDKYIEQIHRQNEEYFNRTGKRKLVFTQ
                     TFGCQMNEHDSEKLCSMLEEMGYQMSMMVEESDLIIYNTCAVRENAELKVYGNLGQLK
                     HLKGKNPDMKIAVCGCMMQQPHVVEELRKKYKHVDLIFGTHNLYKFPQLLTESINSDK
                     MLVDVWDVDGEVIEGLRSNRKFELKAFVNIMYGCNNFCTYCIVPYTRGRERSRTPEDI
                     INEIKELVANGTKEITLLGQNVDSYGKTLENPVSFSELLRKVNDIEGIERVRFMTSHP
                     KDISDEVIYAIRDCDKVCEFLHLPIQCGSSSLLKKMNRHYTKEYYLEIIEKAKKEVPG
                     IAFSTDLMIGFPGETEEDLLDTLDVVEKVRYDSAFTFIYSKRQGTPAAKMENQIPEDI
                     KHDRFNRVLEAVNRISAEINDGYKDRIVEVLVEGRSKNNENKFAGRTRQNKLVNFEGG
                     NDDLIGKLVMVKITEPRTFSLNGILVNN"
BASE COUNT          689 a          164 c          294 g          461 t
ORIGIN      
        1 aactagaaaa ataataatat ctttaaaaga tttttcttat ttgatataat taaggttatg
       61 tgtaatataa gaaattaact aggaggaata gacgtgagca aaagaaaaca agtaacaata
      121 cctatagaga aaatacaaga acaagataaa tatatagaac aaatacacag acaaaatgaa
      181 gaatacttca acagaactgg aaagagaaaa ctcgtgttta ctcaaacctt tgggtgtcaa
      241 atgaatgaac atgattcaga aaaattatgt tcaatgttag aagagatggg ataccaaatg
      301 tcaatgatgg ttgaagaaag tgatttaata atatataaca cctgtgcagt tagagaaaat
      361 gcagagctaa aagtatatgg taacttagga caattaaaac atctaaaagg aaaaaatcca
      421 gatatgaaaa tagctgtatg tggatgtatg atgcaacaac cacatgttgt agaggaatta
      481 agaaaaaaat ataaacatgt agaccttata tttggaacac ataatctata taaatttccg
      541 caattactta cagaatcaat aaattctgac aaaatgttag tggatgtatg ggatgtggat
      601 ggagaagtaa tagaaggtct tagaagtaat agaaaatttg aattaaaagc atttgtaaat
      661 ataatgtatg gatgcaataa tttctgcaca tattgtatag tcccatacac aagaggaaga
      721 gaaagaagta gaactcctga agatataatt aacgagataa aagagcttgt tgcaaatgga
      781 acgaaagaaa tcactttact tggacaaaat gtagattctt atggtaagac acttgaaaat
      841 ccagtttcat tctcagaact tttaagaaaa gtgaatgata tagaaggaat tgaaagggtt
      901 cgatttatga catctcatcc aaaagatata tctgatgaag taatatacgc aattagagat
      961 tgtgataagg tgtgtgagtt tttacatcta ccaatacaat gcggaagcag tagccttttg
     1021 aaaaaaatga atagacatta tacaaaggaa tattatttag aaataataga aaaagctaaa
     1081 aaggaagttc caggtattgc tttttctaca gacttaatga ttggtttccc aggagaaaca
     1141 gaagaagatt tattggacac tttagatgtg gttgaaaaag ttagatatga ttcagctttt
     1201 acatttattt attctaaaag acagggaact cctgctgcta aaatggaaaa tcaaatacca
     1261 gaagatataa agcatgatag atttaatagg gtgttagaag ctgtaaatag gatttctgca
     1321 gaaataaatg atggatataa agatagaata gttgaagttc tagttgaagg aagaagtaaa
     1381 aataatgaaa ataagtttgc tggtagaact agacaaaata aactcgtaaa tttcgaaggt
     1441 ggaaatgatg atttaattgg taaattagtt atggtcaaaa ttactgaacc tagaactttt
     1501 tcattaaatg ggatattagt aaataattaa tattgtacaa aataataaaa ttatgtaaac
     1561 taatcaaaat agatgtacta tagaacaaat tatattaaaa atttttat
//
LOCUS       DAYAOO010000198         1596 bp    DNA     linear   BCT 12-OCT-2024
DEFINITION  TPA_asm: Clostridioides difficile isolate ST8-SSI-h139-18
            SAMN40601845-rid21577343.denovo.202, whole genome shotgun sequence.
ACCESSION   DAYAOO010000198 DAYAOO010000000
VERSION     DAYAOO010000198.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN40601845
            Sequence Read Archive: SRR28438827
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 1596)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1596)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-MAY-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-MAY-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002157583.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002157583.1
            Genome Coverage       :: 163x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/11/2024 16:19:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 4,038
            CDSs (total)                      :: 3,963
            Genes (coding)                    :: 3,930
            CDSs (with protein)               :: 3,930
            Genes (RNA)                       :: 75
            rRNAs                             :: 6, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 60
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 33
            CDSs (without protein)            :: 33
            Pseudo Genes (ambiguous residues) :: 0 of 33
            Pseudo Genes (frameshifted)       :: 7 of 33
            Pseudo Genes (incomplete)         :: 25 of 33
            Pseudo Genes (internal stop)      :: 11 of 33
            Pseudo Genes (multiple problems)  :: 8 of 33
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1596
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN40601845-rid21577343.denovo.202"
                     /isolate="ST8-SSI-h139-18"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Denmark"
                     /collection_date="2018"
                     /collected_by="Statens Serum Institute"
     gene            172..831
                     /gene="cprR"
                     /locus_tag="ACGI5H_003920"
     CDS             172..831
                     /gene="cprR"
                     /locus_tag="ACGI5H_003920"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437316.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system response regulator CprR"
                     /protein_id="HFG9699591.1"
                     /translation="MSKILVVDDELDMLKLIENVLKRDGHEVKVISDVEKAMNMDFNY
                     FNLIILDVMMPKMDGFEVCKTIRNKVDCPILFLTAKNMESDIMYGLGIGADDYITKPF
                     GVGELRARITAHLRRESREKKNLLTISNVQFNFLGKEVSIDGKKINFTKSEYLICEFL
                     AKNKGQVFSKERIYESVYGFDGESDISTITEHIKNIRSKLKQYDIYTIETVWGIGYKW
                     V"
     gene            1042..>1596
                     /locus_tag="ACGI5H_003921"
     CDS             1042..>1596
                     /locus_tag="ACGI5H_003921"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417031.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lysylphosphatidylglycerol synthase
                     domain-containing protein"
                     /protein_id="HFG9699592.1"
                     /translation="MDRLKNIRKSLLQYTFLFLLIGITIYLVFKTLDIKMLSNVMVMV
                     DKKFLFIGALAIMCHIMLEGVVMKIIIESTHKVNIRFIGFKLAIMGFYYNLITPFASG
                     SQPVQIYVLKKCKMPLSKASAVVTNKSIIFQIVVTFYCTILVLMNFAMLEKQMKMIMP
                     LVFLGIAINSFVLIMIILVILNPEK"
BASE COUNT          623 a          123 c          277 g          573 t
ORIGIN      
        1 aatacgtgta aaatgaatat aaagtttttg tatctaagat attttatttg taaaatagta
       61 attaattatt gtaagctata atatgagagt attatggtta atgtgaattt taaagatatt
      121 attaaatata taaattagaa tactattaaa cggataaatg gaggagttat tatgtctaag
      181 atattagtag tagatgatga gttagatatg ttaaagttga ttgaaaatgt gttgaaaaga
      241 gatggacatg aagtaaaggt aattagtgat gtagaaaaag ctatgaacat ggattttaat
      301 tattttaatc taataatatt agatgttatg atgcctaaga tggatggttt tgaagtatgt
      361 aaaactataa gaaataaggt tgattgtcca atactgtttt tgacagcaaa aaatatggaa
      421 agtgatatta tgtacggtct tggtataggt gcagatgact atataaccaa accttttggt
      481 gtaggagaat taagggctag gataactgct catttaaggc gagaaagtag agaaaaaaag
      541 aatttattaa ctatctcaaa tgttcaattt aactttttag gcaaagaagt ttcaattgat
      601 ggtaaaaaaa ttaattttac taaaagtgaa tatctaatat gtgaatttct agcaaaaaat
      661 aagggacaag tattttcaaa agaaagaata tatgagtcgg tatatggttt tgatggagaa
      721 agtgatataa gtactatcac agagcatata aaaaatatac gaagcaaatt aaaacaatat
      781 gatatttata caatagaaac tgtatggggg atagggtata aatgggtgta ataagtataa
      841 gtgttgttta gtgaaaatat tatatatatc tacaaaatgt ttgtaaaata ttaatctata
      901 tattaaaatt taatttatag attaatattt tttgtaaatg acaaaattgt aaggtatttt
      961 gttataaaat attaagattc atagtgtata ctaataatat agtatttagt ataaatcttg
     1021 agcaaaggat ggttatttct aatggataga ctaaagaata ttagaaagag tttactacag
     1081 tatacatttt tatttttgtt aataggtata acaatttacc tagtgtttaa aacattggat
     1141 attaaaatgc tatcaaatgt tatggttatg gtagataaga agtttttatt cataggtgct
     1201 ttggcaataa tgtgtcacat aatgcttgaa ggagtagtaa tgaagataat tatagaaagc
     1261 actcacaaag ttaatattag atttattggt tttaagctag ccattatggg attttattat
     1321 aatttaataa ctccttttgc ttcaggaagc caaccagtac agatatatgt acttaaaaaa
     1381 tgtaaaatgc cacttagtaa ggcaagtgca gttgttacca ataagtctat tatcttccaa
     1441 atagtagtta ctttttattg tacaatactt gttttaatga attttgctat gttagaaaaa
     1501 caaatgaaaa tgattatgcc tctagtgttt ctagggatag ccattaattc atttgtctta
     1561 attatgataa tattagttat tttaaatcct gaaaaa
//
LOCUS       DAYAOO010000199         1460 bp    DNA     linear   BCT 12-OCT-2024
DEFINITION  TPA_asm: Clostridioides difficile isolate ST8-SSI-h139-18
            SAMN40601845-rid21577343.denovo.204, whole genome shotgun sequence.
ACCESSION   DAYAOO010000199 DAYAOO010000000
VERSION     DAYAOO010000199.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN40601845
            Sequence Read Archive: SRR28438827
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 1460)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1460)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-MAY-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-MAY-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002157583.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002157583.1
            Genome Coverage       :: 163x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/11/2024 16:19:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 4,038
            CDSs (total)                      :: 3,963
            Genes (coding)                    :: 3,930
            CDSs (with protein)               :: 3,930
            Genes (RNA)                       :: 75
            rRNAs                             :: 6, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 60
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 33
            CDSs (without protein)            :: 33
            Pseudo Genes (ambiguous residues) :: 0 of 33
            Pseudo Genes (frameshifted)       :: 7 of 33
            Pseudo Genes (incomplete)         :: 25 of 33
            Pseudo Genes (internal stop)      :: 11 of 33
            Pseudo Genes (multiple problems)  :: 8 of 33
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1460
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN40601845-rid21577343.denovo.204"
                     /isolate="ST8-SSI-h139-18"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Denmark"
                     /collection_date="2018"
                     /collected_by="Statens Serum Institute"
     gene            210..431
                     /locus_tag="ACGI5H_003922"
     CDS             210..431
                     /locus_tag="ACGI5H_003922"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429541.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="spore coat associated protein CotJA"
                     /protein_id="HFG9699593.1"
                     /translation="MGYLKEDKQDYCCEFARPYINRQIYDDTYNPKTALKRGTLFPEL
                     DLIESNNYNDWLYANPKNRVRAKKGGNMY"
     gene            431..694
                     /locus_tag="ACGI5H_003923"
     CDS             431..694
                     /locus_tag="ACGI5H_003923"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438891.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="spore coat protein CotJB"
                     /protein_id="HFG9699594.1"
                     /translation="MSLNRRELLERISEYQFACIELNLYLDNNPRDKKALDSYNRYCD
                     KFTQAVCDYESKYGALTNFGYESSEYPWSWISEPWPWDKSFYK"
     gene            756..1328
                     /locus_tag="ACGI5H_003924"
     CDS             756..1328
                     /locus_tag="ACGI5H_003924"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438889.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="manganese catalase family protein"
                     /protein_id="HFG9699595.1"
                     /translation="MWIYQKTLEHPVNIRQADPRMAKYIMTQLGGPNGELAAATRYLQ
                     QRYTMPTGKSRALLTDIGTEEMAHVEIISSVLYQLIGNCTPEELKAAGLGSNYANFGH
                     GLQPVDSNGVNFTTSYINVFGDSVTDLHEDMAAEQKALATYYQLINLTDDPDLKDILR
                     FLGEREVVHYQRFGEALMDVYEFTECKHQF"
BASE COUNT          575 a          168 c          257 g          460 t
ORIGIN      
        1 tgtataaact ctatattatt tatttaaaat agatatttat gaaagattaa ttagaaaaat
       61 tttagaggta aaataagaaa aaaagatact tatttaatca tttaatctta ttaaagacct
      121 attaaaacta ccagttataa tatagaacca gtatacaatt tttaaaaata atgctatttt
      181 aaaattctaa aaattaagga ggataattaa tgggatattt aaaagaggat aaacaagact
      241 attgttgtga atttgctaga ccatacatca atcgtcaaat ttatgatgac acatacaatc
      301 caaaaacagc attaaaaaga ggtactttat ttcctgaatt agatttaata gagtcaaata
      361 actataatga ttggctatat gcaaatccta aaaatagagt tagagctaaa aaagggggta
      421 acatgtacta atgtcattaa atagaagaga acttttagag agaatttcag aatatcaatt
      481 tgcctgtata gaattaaatt tatatttaga taacaatcca agggataaga aagctcttga
      541 ttcatacaac agatactgcg ataaatttac acaagctgtg tgtgattatg aatctaaata
      601 tggagcatta actaattttg gatatgaatc aagtgaatat ccttggtcat ggatatctga
      661 accttggcca tgggacaaat cattttataa ataaaattat taaactttaa aattagattt
      721 attattaaat atatattaag gaggagtaag ataatatgtg gatttatcaa aaaacactgg
      781 aacatccagt taacataaga caagcagacc ctagaatggc aaaatatatc atgactcagt
      841 tgggaggacc taatggtgag ttggcagctg caactagata tcttcaacaa agatatacta
      901 tgccaactgg aaaatctcgt gcacttttaa ctgatatagg tacagaggaa atggctcatg
      961 ttgagataat ttcttcagtg ttatatcaat taataggcaa ttgtactcca gaagagctta
     1021 aggctgctgg acttggtagt aattatgcta attttggaca tggtcttcag ccagtagatt
     1081 ctaatggagt aaactttact acaagttata ttaatgtctt tggcgattcg gtaactgatt
     1141 tacatgagga tatggctgct gaacaaaaag cattggctac gtactatcaa ttaataaatt
     1201 taactgatga ccctgatttg aaagatatat tgagattttt gggtgagagg gaagtagttc
     1261 actatcaaag atttggtgaa gcattaatgg atgtttatga gtttacagag tgcaagcatc
     1321 agttttaatg aagaattgaa agtgaatgga gaataagcat cagttttaat aaagaattaa
     1381 aagtgaacag agaataagca tcatttttaa tgaagaatca aaagtgaatg gagaataagc
     1441 atcattttta atgaagaatt
//
LOCUS       DAYAOO010000200         1362 bp    DNA     linear   BCT 12-OCT-2024
DEFINITION  TPA_asm: Clostridioides difficile isolate ST8-SSI-h139-18
            SAMN40601845-rid21577343.denovo.205, whole genome shotgun sequence.
ACCESSION   DAYAOO010000200 DAYAOO010000000
VERSION     DAYAOO010000200.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN40601845
            Sequence Read Archive: SRR28438827
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 1362)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1362)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-MAY-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-MAY-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002157583.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002157583.1
            Genome Coverage       :: 163x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/11/2024 16:19:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 4,038
            CDSs (total)                      :: 3,963
            Genes (coding)                    :: 3,930
            CDSs (with protein)               :: 3,930
            Genes (RNA)                       :: 75
            rRNAs                             :: 6, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 60
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 33
            CDSs (without protein)            :: 33
            Pseudo Genes (ambiguous residues) :: 0 of 33
            Pseudo Genes (frameshifted)       :: 7 of 33
            Pseudo Genes (incomplete)         :: 25 of 33
            Pseudo Genes (internal stop)      :: 11 of 33
            Pseudo Genes (multiple problems)  :: 8 of 33
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1362
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN40601845-rid21577343.denovo.205"
                     /isolate="ST8-SSI-h139-18"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Denmark"
                     /collection_date="2018"
                     /collected_by="Statens Serum Institute"
     gene            complement(<1..784)
                     /locus_tag="ACGI5H_003925"
     CDS             complement(<1..784)
                     /locus_tag="ACGI5H_003925"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894307.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase"
                     /protein_id="HFG9699596.1"
                     /translation="MKIAIVPGHTLSGKGTGATGYIDEGKENRILTDLIVKWLKQGGA
                     IVYTGKVDKSNNYLAEQCKIANRQNVDLAVQIHFNANKTTLNPMGTETIYKTNNGKVY
                     AERVNDKLATVFENRGAKSDVRGLYWLKHTKAPAILIEVCFVDSKADTDYYIKNKNTV
                     AKLIAEGILNKNINNKENGEGKIMYKHTIVYDGEVDKIPATVVGWGYNDGKILICDIK
                     DYVPGQTQNLYVVGGGACEKISSMTKENYTMIKGNDRFDTLHK"
     gene            complement(784..1041)
                     /locus_tag="ACGI5H_003926"
     CDS             complement(784..1041)
                     /locus_tag="ACGI5H_003926"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889440.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phage holin family protein"
                     /protein_id="HFG9699597.1"
                     /translation="MDNLISFIPEQLLLLVVALNVLGFGFKKYKQLDNKYIPIILLVI
                     GIGFSIWMLGFNPSSILQGILCWGVAIGANQVYKQLKDGDK"
     gene            complement(1061..1291)
                     /locus_tag="ACGI5H_003927"
     CDS             complement(1061..1291)
                     /locus_tag="ACGI5H_003927"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426807.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hemolysin XhlA family protein"
                     /protein_id="HFG9699598.1"
                     /translation="MNEELVKEKISTLETRVKEHGKQIDRIEIEQAKFAIQIQNLCSD
                     IKNLTGVLKWLVGVIITTLVGFFIFAIQKGIF"
BASE COUNT          383 a          273 c          152 g          554 t
ORIGIN      
        1 ctttgtgaag tgtatcaaat ctatcattac cttttatcat agtataattt tctttagtca
       61 tagaacttat cttttcacat gctccaccac caacaacata aagattttgt gtctggccag
      121 gtacataatc ttttatatca catatcagta ttttcccatc attatagccc cagccaacta
      181 cagttgcagg tattttgtca acttctccat cataaacgat tgtatgtttg tacatgattt
      241 ttccctcacc attctctttg ttatttatat ttttatttaa tataccctct gctataagtt
      301 ttgcaactgt atttttattt ttaatataat aatctgtatc tgctttacta tctacgaagc
      361 acacctcaat caatatcgct ggagcttttg tatgcttaag ccagtaaaga cctcttacat
      421 ctgattttgc acctctattt tcgaatactg ttgctaattt atcattaact ctttcggcat
      481 ataccttacc attgttagtt ttgtatattg tctctgtacc cataggattt agagttgttt
      541 tatttgcgtt gaaatggatt tgtactgcta agtctacatt ttgcctattt gcaattttac
      601 attgttctgc taagtagtta ttagatttat ctacttttcc agtatacaca atagctccac
      661 cttgtttcaa ccatttaaca attaaatcag ttaaaattct attttctttt ccttcgtcta
      721 tatagccagt tgctcctgtt ccttttccac ttaaagtgtg tcctggtact attgctattt
      781 tcattattta tcaccatcct tcaactgttt gtaaacttga tttgccccta ttgcaactcc
      841 ccaacataaa attccttgta aaattgatga aggattaaat cctaacatcc atattgaaaa
      901 tccaattcct atcacaagca atatgattgg aatgtattta ttatctaact gtttgtattt
      961 cttaaatcca aatcctaata cattaagagc aactactaat aaaagcagtt gctctggtat
     1021 aaaacttatt aaattatcca tatcttaacc tcctaattaa ttaaaatatt cctttctgta
     1081 tggcaaatat aaagaaccct actaaagttg taattataac tcctacaagc cacttgagta
     1141 ctcctgtcag attttttata tcactacata ggttttgtat ttgtatagca aactttgctt
     1201 gctcaatctc gattctatca atttgtttgc cgtgttcttt tactcttgtt tcaagtgtac
     1261 ttattttttc tttcacaagt tcttcattca tgaaaacctc ctattgcttt gtattaaaaa
     1321 aagaacatta cctattttgt aagttctgct ccttctacta cc
//
LOCUS       DAYAOO010000201         1337 bp    DNA     linear   BCT 12-OCT-2024
DEFINITION  TPA_asm: Clostridioides difficile isolate ST8-SSI-h139-18
            SAMN40601845-rid21577343.denovo.206, whole genome shotgun sequence.
ACCESSION   DAYAOO010000201 DAYAOO010000000
VERSION     DAYAOO010000201.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN40601845
            Sequence Read Archive: SRR28438827
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 1337)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1337)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-MAY-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-MAY-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002157583.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002157583.1
            Genome Coverage       :: 163x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/11/2024 16:19:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 4,038
            CDSs (total)                      :: 3,963
            Genes (coding)                    :: 3,930
            CDSs (with protein)               :: 3,930
            Genes (RNA)                       :: 75
            rRNAs                             :: 6, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 60
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 33
            CDSs (without protein)            :: 33
            Pseudo Genes (ambiguous residues) :: 0 of 33
            Pseudo Genes (frameshifted)       :: 7 of 33
            Pseudo Genes (incomplete)         :: 25 of 33
            Pseudo Genes (internal stop)      :: 11 of 33
            Pseudo Genes (multiple problems)  :: 8 of 33
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1337
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN40601845-rid21577343.denovo.206"
                     /isolate="ST8-SSI-h139-18"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Denmark"
                     /collection_date="2018"
                     /collected_by="Statens Serum Institute"
     gene            27..101
                     /locus_tag="ACGI5H_003928"
     tRNA            27..101
                     /locus_tag="ACGI5H_003928"
                     /product="tRNA-Thr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:59..61,aa:Thr,seq:tgt)
     gene            116..200
                     /locus_tag="ACGI5H_003929"
     tRNA            116..200
                     /locus_tag="ACGI5H_003929"
                     /product="tRNA-Tyr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:150..152,aa:Tyr,seq:gta)
     gene            210..293
                     /locus_tag="ACGI5H_003930"
     tRNA            210..293
                     /locus_tag="ACGI5H_003930"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:244..246,aa:Leu,seq:tag)
     gene            323..399
                     /locus_tag="ACGI5H_003931"
     tRNA            323..399
                     /locus_tag="ACGI5H_003931"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:357..359,aa:Arg,seq:tct)
     gene            407..482
                     /locus_tag="ACGI5H_003932"
     tRNA            407..482
                     /locus_tag="ACGI5H_003932"
                     /product="tRNA-Gln"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:440..442,aa:Gln,seq:ttg)
     gene            571..659
                     /locus_tag="ACGI5H_003933"
     tRNA            571..659
                     /locus_tag="ACGI5H_003933"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:605..607,aa:Ser,seq:tga)
     gene            663..738
                     /locus_tag="ACGI5H_003934"
     tRNA            663..738
                     /locus_tag="ACGI5H_003934"
                     /product="tRNA-Phe"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:696..698,aa:Phe,seq:gaa)
     gene            745..818
                     /locus_tag="ACGI5H_003935"
     tRNA            745..818
                     /locus_tag="ACGI5H_003935"
                     /product="tRNA-Met"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:779..781,aa:Met,seq:cat)
     gene            833..909
                     /locus_tag="ACGI5H_003936"
     tRNA            833..909
                     /locus_tag="ACGI5H_003936"
                     /product="tRNA-Ile"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:867..869,aa:Ile,seq:cat)
     gene            933..1009
                     /locus_tag="ACGI5H_003937"
     tRNA            933..1009
                     /locus_tag="ACGI5H_003937"
                     /product="tRNA-Pro"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:967..969,aa:Pro,seq:tgg)
     gene            1017..1093
                     /locus_tag="ACGI5H_003938"
     tRNA            1017..1093
                     /locus_tag="ACGI5H_003938"
                     /product="tRNA-His"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1051..1053,aa:His,seq:gtg)
     gene            1102..1177
                     /locus_tag="ACGI5H_003939"
     tRNA            1102..1177
                     /locus_tag="ACGI5H_003939"
                     /product="tRNA-Lys"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1135..1137,aa:Lys,seq:ttt)
     gene            1185..1258
                     /locus_tag="ACGI5H_003940"
     tRNA            1185..1258
                     /locus_tag="ACGI5H_003940"
                     /product="tRNA-Cys"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1217..1219,aa:Cys,seq:gca)
     gene            1265..1336
                     /locus_tag="ACGI5H_003941"
     tRNA            1265..1336
                     /locus_tag="ACGI5H_003941"
                     /product="tRNA-Asn"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1297..1299,aa:Asn,seq:gtt)
BASE COUNT          321 a          309 c          355 g          352 t
ORIGIN      
        1 ccccttccag gtcgccaaaa taaaatgctg gtgtggctca acggtagagc agctgacttg
       61 taatcagcag gttgtaggtt cgattcctat caccagctcc atgtaaaatt aatacggagg
      121 atttcccgag cggccaaagg gggcagactg taaatctgtt gtcatcgact tcggtggttc
      181 gaatccacca tcctccacca aaaaaatgcg cggatgtggc ggaattggca gacgcactag
      241 acttaggatc tagcgccatt ggcgtggggg ttcgactccc ttcatccgca ccatttttgt
      301 ttgatataca tatataaatt gtgggtgcat agctcagctg gatagagcaa cgcccttcta
      361 aggcgtgtgt ccggggttcg aatccctgtg cgctcaccac atatattggg gattagccaa
      421 gtcggtaagg cacatgactt tgactcatgt atgcgtaggt tcgagtcctg catccccagc
      481 caaatgatgt attactaagc tatatttgaa ttatttttat tttaaatata gttaggttca
      541 attttagaat aagtttaagt atccgaatgt ggagaggtgt ccgagtggtt taaggagctg
      601 gtcttgaaaa ccagtgactt cgaaaggggc cgtgggttcg aatcccaccc tctccgccaa
      661 atgcccagat agctcagtcg gtagagcagg ggactgaaaa tccccgtgtc ggtggttcga
      721 ttccgcctct gggcaccaaa atatggcggt atagcttagt tggctagagc gttcggttca
      781 tacccgaaag gtcataggtt cgactcctat taccgctact aaaatttaat gtgggccatt
      841 agctcagttg gttagagcgc ccggctcata accggtaggt ctggggttcg agtccctgat
      901 ggcccaccac attaaattaa ttaatataaa ttcgaggtgt agcgcagttt ggtagcgcac
      961 atggtttggg accatggggc cgggggttcg agtcccttca cctcgaccaa tataaggtgg
     1021 gtatagctca gttggttaga gcgccagatt gtggctctgg aggtcgtgag ttcgactctc
     1081 attatccacc ccaattcata tggtctatta gctcagtcgg tagagcacct gacttttaat
     1141 cagggtgtcc cgcgttcgag tcgcggatag atcaccaaaa aggtggcgac atagccaagt
     1201 ggtaaggcag tggactgcaa ctccttgatc cccagttcga atctgggtgt cgcctccaaa
     1261 atattccaag gtagctcaac ggtggagcaa ccggctgtta accggtaggc tgtgggttcg
     1321 agccccaccc ttggagc
//
LOCUS       DAYAOO010000202         1298 bp    DNA     linear   BCT 12-OCT-2024
DEFINITION  TPA_asm: Clostridioides difficile isolate ST8-SSI-h139-18
            SAMN40601845-rid21577343.denovo.207, whole genome shotgun sequence.
ACCESSION   DAYAOO010000202 DAYAOO010000000
VERSION     DAYAOO010000202.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN40601845
            Sequence Read Archive: SRR28438827
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 1298)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1298)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-MAY-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-MAY-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002157583.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002157583.1
            Genome Coverage       :: 163x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/11/2024 16:19:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 4,038
            CDSs (total)                      :: 3,963
            Genes (coding)                    :: 3,930
            CDSs (with protein)               :: 3,930
            Genes (RNA)                       :: 75
            rRNAs                             :: 6, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 60
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 33
            CDSs (without protein)            :: 33
            Pseudo Genes (ambiguous residues) :: 0 of 33
            Pseudo Genes (frameshifted)       :: 7 of 33
            Pseudo Genes (incomplete)         :: 25 of 33
            Pseudo Genes (internal stop)      :: 11 of 33
            Pseudo Genes (multiple problems)  :: 8 of 33
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1298
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN40601845-rid21577343.denovo.207"
                     /isolate="ST8-SSI-h139-18"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Denmark"
                     /collection_date="2018"
                     /collected_by="Statens Serum Institute"
     gene            complement(52..489)
                     /locus_tag="ACGI5H_003942"
     CDS             complement(52..489)
                     /locus_tag="ACGI5H_003942"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895641.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LytTR family DNA-binding domain-containing
                     protein"
                     /protein_id="HFG9699599.1"
                     /translation="MKIHVEQGINCDDIEITIKCSALDNNIEKIISLLSIPLLDIKGK
                     KSGEIYKLNVCDILYFETVGNKTFAYYEDDVFEIDLKIYKLSKLLANTSFSRISKSMI
                     LNMDYIKSIKVISHNRMQATLKNNEKVIINRRYIKNIKEKLNI"
     gene            complement(746..895)
                     /locus_tag="ACGI5H_003943"
     CDS             complement(746..895)
                     /locus_tag="ACGI5H_003943"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429511.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YvrJ family protein"
                     /protein_id="HFG9699600.1"
                     /translation="MDDSLQLLITNVGFPIALSMYLLVRIEGKLNTLSNSIDTLSKNI
                     LIFKK"
     gene            complement(908..1138)
                     /locus_tag="ACGI5H_003944"
     CDS             complement(908..1138)
                     /locus_tag="ACGI5H_003944"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437662.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2922 domain-containing protein"
                     /protein_id="HFG9699601.1"
                     /translation="MEIKKKLVMSFKNVKDKQVSFSIENPKDDLTEENIKSVMDLIVS
                     KNIFSVGGFDLASVVEAKVVETNTTPYDLVIE"
BASE COUNT          453 a          172 c          140 g          533 t
ORIGIN      
        1 aggtcaataa atttgcaatt agtgatatta ataaattact ttagattttt attaaatgtt
       61 tagcttttct ttaatatttt ttatataacg acgatttata ataacttttt cgttgttttt
      121 taaagtagct tgcatgcgat tatgtgatat tacttttata ctttttatgt agtccatatt
      181 taaaatcatg gatttagata ttcgtgagaa agatgtatta gctaataatt ttgataattt
      241 atatattttt aaatcaattt caaatacatc atcttcataa taagcaaatg ttttatttcc
      301 aactgtctca aagtataaaa tatcacagac attgagttta taaatctctc ctgatttttt
      361 accttttata tcaagtaacg gtatactcaa taatgaaatt attttttcaa tgttattatc
      421 tagagcagaa cattttatgg ttatttcaat atcatcacaa ttaatacctt gttcgacatg
      481 tattttcatt aatcatcacc tcattttatt actgtcatta gaatagcatt atatcttatt
      541 gagtccaact agatgcgttc taaatttcaa attaagcata gtgaaattca aaaataaaac
      601 agtgaaattc aaatttgagg tggtaaaatt caaaaaaata ctatggatat ttggataaat
      661 tatccaaata tcctagtatt tcacatagaa tatgtctaat tattttacaa atagacctat
      721 tttatgactt acatatattg tcaaattact tcttaaatat caaaatattt ttggataatg
      781 tatcaatact gtttgataaa gtatttaatt taccctcaat tctaaccaac aagtacatgg
      841 atagagctat aggaaaacca acattggtta ttaacagttg taaactatca tccataaaat
      901 tagcccccta ttctataact aagtcataag gagtggtatt tgtttccaca accttggctt
      961 caacaacaga agctaggtca aatcctccaa ccgaaaaaat atttttagat actatcaaat
     1021 ccatgacaga ttttatattt tcttcagtta aatcatcctt tggattttct atagaaaaag
     1081 aaacttgttt atcctttaca tttttaaagc tcatgactaa ttttttctta atttccatat
     1141 aattacctcc gatataataa tttatatttt aattgtttgc ttgttaatat tggtatttta
     1201 attatcaata ttaatgtttt gcttgttagt attaatattt caattgtcaa tattaatgtt
     1261 ttgcttgtta gtattaatat ttcaattgtc aatattag
//
LOCUS       DAYAOO010000203         1271 bp    DNA     linear   BCT 12-OCT-2024
DEFINITION  TPA_asm: Clostridioides difficile isolate ST8-SSI-h139-18
            SAMN40601845-rid21577343.denovo.208, whole genome shotgun sequence.
ACCESSION   DAYAOO010000203 DAYAOO010000000
VERSION     DAYAOO010000203.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN40601845
            Sequence Read Archive: SRR28438827
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 1271)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1271)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-MAY-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-MAY-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002157583.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002157583.1
            Genome Coverage       :: 163x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/11/2024 16:19:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 4,038
            CDSs (total)                      :: 3,963
            Genes (coding)                    :: 3,930
            CDSs (with protein)               :: 3,930
            Genes (RNA)                       :: 75
            rRNAs                             :: 6, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 60
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 33
            CDSs (without protein)            :: 33
            Pseudo Genes (ambiguous residues) :: 0 of 33
            Pseudo Genes (frameshifted)       :: 7 of 33
            Pseudo Genes (incomplete)         :: 25 of 33
            Pseudo Genes (internal stop)      :: 11 of 33
            Pseudo Genes (multiple problems)  :: 8 of 33
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1271
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN40601845-rid21577343.denovo.208"
                     /isolate="ST8-SSI-h139-18"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Denmark"
                     /collection_date="2018"
                     /collected_by="Statens Serum Institute"
     gene            complement(<1..909)
                     /locus_tag="ACGI5H_003945"
     CDS             complement(<1..909)
                     /locus_tag="ACGI5H_003945"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860734.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNRLRE domain-containing protein"
                     /protein_id="HFG9699602.1"
                     /translation="MRNIILYLNDDTFISKKYPDKNFSNLDYCLIGSKCSNSFVKEKL
                     ITFFKVRIPDILKDKSILKAELFIHIDSNKNHIFKEKVDIEIKRISEYYNLRTITWND
                     RVSMENIRGYLPVGISDTSNYICLNITGTIKAWAMNKYPNYGLALSLNYPYQILEFTS
                     SRGCNKPYILVTFEDRIIDNCYPKCECLPIRITGPMGPRGATGSTGPTGVTGPTGSTG
                     ATGSIGPTGPTGNTGATGSIGPTGVTGPTGSTGATGSIGPTGVTGPTGNTGEIGPTGA
                     TGPTGVTGSIGPTGATGPTGEIGPTGA"
BASE COUNT          361 a          233 c          157 g          520 t
ORIGIN      
        1 tgctcccgtt ggtcctattt ctcctgttgg tcctgttgct cctgttggtc ctatacttcc
       61 tgtcactcct gttggacctg ttgctcccgt tggtcctatt tctcctgtat ttcctgttgg
      121 gcctgttact cctgttggtc ctatacttcc tgtcgctcct gtacttccgg ttgggcctgt
      181 tactcccgtt ggccctatac ttcctgttgc tcctgtattt ccggttgggc ctgttggtcc
      241 tatgcttcct gtcgctcctg tacttccggt tgggcctgtt actcccgttg gtcctgtact
      301 tcctgtcgct cctcttggtc ccattggacc tgtaattcta attggaagac actcacattt
      361 aggataacaa ttatctataa ttctatcttc aaatgttaca agtatatacg gtttgttaca
      421 acctctacta gatgtaaatt caagaatctg ataagggtaa tttaaagata aagctaaccc
      481 ataattagga tatttattca ttgcccatgc ttttatagtt cccgtaatat ttaaacaaat
      541 atagttggat gtatcactta tcccaactgg taaatatccc ctaatatttt ccatagacac
      601 tctatcattc catgttatag ttcgtaaatt ataatattca cttattcttt taatttcaat
      661 atctactttt tctttaaaaa tatgattctt atttgaatca atatgaataa ataactctgc
      721 ttttaatata cttttgtctt ttaatatatc tggtattctc actttaaaaa aagtaatcaa
      781 cttttctttt acaaaactat ttgaacattt acttcctatt aagcaataat ctaaattact
      841 aaagttttta tctggatatt ttttagatat aaaagtatca tcatttaaat aaagtataat
      901 atttctcatt tataatccct ccattttggg tctatatcat actatgttta aaatacatgc
      961 ttagttacaa tataattaaa atttatagta ttaaattttt atataataat gctgatttct
     1021 acaaaaaaag aacatgtcat tagaaatttc taatagcatg ttctttttca ttattatata
     1081 ttacacttta aattattcct tgactggctt agctggtgta aactaaacca gtctttctaa
     1141 aatattaagc acttttttct tattatgttt tttaggattt attgtctata ttattgtaaa
     1201 ccaaagttat aaaattgtaa atagaatata ttaccataac aatatctttt tataagtaaa
     1261 aattataaaa a
//
LOCUS       DAYAOO010000204         1213 bp    DNA     linear   BCT 12-OCT-2024
DEFINITION  TPA_asm: Clostridioides difficile isolate ST8-SSI-h139-18
            SAMN40601845-rid21577343.denovo.209, whole genome shotgun sequence.
ACCESSION   DAYAOO010000204 DAYAOO010000000
VERSION     DAYAOO010000204.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN40601845
            Sequence Read Archive: SRR28438827
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 1213)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1213)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-MAY-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-MAY-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002157583.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002157583.1
            Genome Coverage       :: 163x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/11/2024 16:19:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 4,038
            CDSs (total)                      :: 3,963
            Genes (coding)                    :: 3,930
            CDSs (with protein)               :: 3,930
            Genes (RNA)                       :: 75
            rRNAs                             :: 6, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 60
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 33
            CDSs (without protein)            :: 33
            Pseudo Genes (ambiguous residues) :: 0 of 33
            Pseudo Genes (frameshifted)       :: 7 of 33
            Pseudo Genes (incomplete)         :: 25 of 33
            Pseudo Genes (internal stop)      :: 11 of 33
            Pseudo Genes (multiple problems)  :: 8 of 33
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1213
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN40601845-rid21577343.denovo.209"
                     /isolate="ST8-SSI-h139-18"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Denmark"
                     /collection_date="2018"
                     /collected_by="Statens Serum Institute"
     gene            101..1141
                     /locus_tag="ACGI5H_003946"
     CDS             101..1141
                     /locus_tag="ACGI5H_003946"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424562.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M42 family metallopeptidase"
                     /protein_id="HFG9699603.1"
                     /translation="MNLNLTNTINLMKKYLDIPSPAGYTENAVLEIKKDFENLSLDTI
                     LTKKGALIATLPGEDDSNQITISAHMDTLGAIVKEISSDGTLKYHKVGGGCWAAIEGE
                     NCTVITRKGKKIRGSVVFKYASTHIYGQTKAATERNEETMIIRLDEKVFTKQDVLDLG
                     ISVGDFVCLDHRFEATESGFIKSRYIDNKSAVAMVLEICRYFKENNLTPKHTTNFYIS
                     NYEEIGHGVSKCLPEKTKEFVAIDIAPTGPSQTSSEHGVTIVAKDNLSLYDFNLRNKL
                     VDVAEDNNLDYAVDVFTFYGSDASEAIRWGEDVQIACVGPGTNNSHHYERTHIEAIEN
                     TLKLLINYMLKE"
BASE COUNT          471 a          142 c          195 g          405 t
ORIGIN      
        1 ttttaaatat gtttagattc tattctttta attttagttt tcagaacatt tgtatttatg
       61 ttataatttg tataaatata tttatttagg aggaaacaat atgaatttaa atttaactaa
      121 tactataaat ttaatgaaaa aatatttgga cattccaagc ccagctggat atactgaaaa
      181 tgcagtttta gaaatcaaaa aagattttga aaatttaagt cttgacacta ttcttacaaa
      241 aaaaggtgca cttatagcta ctcttcctgg tgaagatgat tcaaatcaaa taacaatatc
      301 tgcacatatg gatacacttg gagctatagt aaaagaaata tcatctgatg gtactcttaa
      361 ataccataaa gttggtggtg gatgttgggc ggctatagag ggagaaaact gtactgttat
      421 aactagaaaa ggtaaaaaaa tcagaggaag tgttgtattt aagtatgctt ctactcatat
      481 atatggtcaa acaaaagctg ccactgaaag aaatgaagaa acaatgatta ttagacttga
      541 tgaaaaagta tttacaaagc aagatgtatt agatttagga ataagtgttg gggattttgt
      601 atgcctagac catagatttg aggctacaga atctggtttt ataaaatcta gatatataga
      661 taataaatca gctgtagcaa tggttcttga aatatgtaga tattttaaag aaaacaattt
      721 aacacctaag catactacta acttttatat aagtaattat gaagaaattg gacatggtgt
      781 ttctaaatgt ttacctgaaa aaacaaaaga atttgtagca atagatatag cacctactgg
      841 accaagtcaa acatctagtg aacatggtgt aactatagtt gcaaaagata atttatcatt
      901 atatgatttt aatttaagaa acaagcttgt cgatgttgca gaagacaata atttagacta
      961 cgctgtcgat gtatttactt tctatggttc agatgcttca gaagctattc gttggggaga
     1021 agatgttcaa atagcatgtg ttggtcctgg aacaaacaat agtcaccatt atgaaagaac
     1081 acatatagaa gctattgaaa atacactaaa attacttata aattatatgc ttaaagaata
     1141 attaattata tattttacca aagtcaattc ttaacaaata attaacttta atttttattt
     1201 ttatacaaaa att
//
LOCUS       DAYAOO010000205         1206 bp    DNA     linear   BCT 12-OCT-2024
DEFINITION  TPA_asm: Clostridioides difficile isolate ST8-SSI-h139-18
            SAMN40601845-rid21577343.denovo.210, whole genome shotgun sequence.
ACCESSION   DAYAOO010000205 DAYAOO010000000
VERSION     DAYAOO010000205.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN40601845
            Sequence Read Archive: SRR28438827
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 1206)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1206)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-MAY-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-MAY-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002157583.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002157583.1
            Genome Coverage       :: 163x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/11/2024 16:19:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 4,038
            CDSs (total)                      :: 3,963
            Genes (coding)                    :: 3,930
            CDSs (with protein)               :: 3,930
            Genes (RNA)                       :: 75
            rRNAs                             :: 6, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 60
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 33
            CDSs (without protein)            :: 33
            Pseudo Genes (ambiguous residues) :: 0 of 33
            Pseudo Genes (frameshifted)       :: 7 of 33
            Pseudo Genes (incomplete)         :: 25 of 33
            Pseudo Genes (internal stop)      :: 11 of 33
            Pseudo Genes (multiple problems)  :: 8 of 33
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1206
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN40601845-rid21577343.denovo.210"
                     /isolate="ST8-SSI-h139-18"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Denmark"
                     /collection_date="2018"
                     /collected_by="Statens Serum Institute"
     gene            complement(301..792)
                     /locus_tag="ACGI5H_003947"
     CDS             complement(301..792)
                     /locus_tag="ACGI5H_003947"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729184.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YfbM family protein"
                     /protein_id="HFG9699604.1"
                     /translation="MGMIGCYTKISEENVFKLQQAEENLQDFVFEDANENSTINIDKA
                     WHAIHFTLTGCPFGGDDDNIFSKLVLSGNILMEIDGEFPVMLITANDVKKLSKAMNSL
                     EEQAFRKRFNINEMLENNIYPVMNDESEDDFFEYVWANLIELKKFIQEASDDGLAVIF
                     FIM"
BASE COUNT          468 a          166 c          113 g          459 t
ORIGIN      
        1 tttatatata atgaaaaatg tgataagtat ccaaaagaat tactggatat aataggatag
       61 ggtatttagc cttttaagat aaataaaaat atctacaact atatattgca aaaatttaaa
      121 actaatttat atatgctaat ataaatattt ataaagacat aagacaaatt tacctacaga
      181 tttaaattta acttatatat tttaaaaggc taatataata tgtattttct tctatacaat
      241 caaaaggctt catatctaag atatgtgatg acactaatat tcacaatttt ttagtaatta
      301 tcacattata aaaaatatta cagctagtcc atcatcagat gcttcttgta taaacttttt
      361 aagctcaatt agatttgccc atacatattc aaaaaaatca tcttcactct catcattcat
      421 aacaggataa atattatttt ctaacatctc attaatatta aatctttttc taaatgcttg
      481 ttcttccaaa ctgttcattg cttttgatag tttttttaca tcatttgctg taatcaacat
      541 gacaggaaat tctccatcaa tttccataag tatgtttcca cttagtacta atttgctaaa
      601 tatattatca tcatctccac caaaaggaca acctgtcaaa gtaaagtgaa tggcatgcca
      661 tgctttatca atattgatag tactattttc gttggcatct tcaaaaacaa aatcttgtaa
      721 gttttcttct gcttgctgta atttaaaaac attctcttca cttattttag tataacatcc
      781 tatcatcccc ataattacat tcctcctaag tagcgttttt ttaattgtaa cttataatta
      841 aacttagtta caataaaata tattgagaaa agtattattt catcttaaat ttaaatacct
      901 atattatcaa ctaaaattct gtgtttatag cgtaagtatt attatttttt cctaaaaatt
      961 aaatgaatca gaagttctat aggcaatatt gactataaat aagaactatt acttttaaaa
     1021 aaaaatttaa gaaattatac tgtagaatca tgctctactt attagcttta aataaaaaat
     1081 aaatcatgtt ctcaaattaa ataataaata acaataaatt taaattttaa actataagag
     1141 tttctgaagt gttaataagc ataccaataa ttatatgtgt aagaatttga tttaatagat
     1201 atgaat
//
LOCUS       DAYAOO010000206         1193 bp    DNA     linear   BCT 12-OCT-2024
DEFINITION  TPA_asm: Clostridioides difficile isolate ST8-SSI-h139-18
            SAMN40601845-rid21577343.denovo.211, whole genome shotgun sequence.
ACCESSION   DAYAOO010000206 DAYAOO010000000
VERSION     DAYAOO010000206.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN40601845
            Sequence Read Archive: SRR28438827
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 1193)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1193)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-MAY-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-MAY-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002157583.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002157583.1
            Genome Coverage       :: 163x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/11/2024 16:19:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 4,038
            CDSs (total)                      :: 3,963
            Genes (coding)                    :: 3,930
            CDSs (with protein)               :: 3,930
            Genes (RNA)                       :: 75
            rRNAs                             :: 6, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 60
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 33
            CDSs (without protein)            :: 33
            Pseudo Genes (ambiguous residues) :: 0 of 33
            Pseudo Genes (frameshifted)       :: 7 of 33
            Pseudo Genes (incomplete)         :: 25 of 33
            Pseudo Genes (internal stop)      :: 11 of 33
            Pseudo Genes (multiple problems)  :: 8 of 33
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1193
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN40601845-rid21577343.denovo.211"
                     /isolate="ST8-SSI-h139-18"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Denmark"
                     /collection_date="2018"
                     /collected_by="Statens Serum Institute"
     gene            <1..1170
                     /locus_tag="ACGI5H_003948"
     CDS             <1..1170
                     /locus_tag="ACGI5H_003948"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419653.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NlpC/P60 family protein"
                     /protein_id="HFG9699605.1"
                     /translation="IINTTFSESMENVKNKVIVVDQYGSKISEKIDNEIFKEVNVIMQ
                     KVIQQQENQDVDIDSEFNGIEKSCSLKGYGDVSCITGRGVKVKDSYTKLVGLFYIDTD
                     KHTWQNGEYQIELELNFQNLMDEKSAGQDEPKEESNLGGEDYAGGKEFTAEFTAYCPR
                     KEEGGDTDCRKKKLDPSKKTCAAPMVGKYEQTYYTKEFLNKHPLLNYGDEIQVITGVS
                     GRDGVYKVNDVGPAITIEKNGTYHIDILFGNVEEASKFGRRKGKIIIGGYSGNVSDKA
                     KIVISEAKKHLGKPYKWGGNGPSSFDCSGLMVYCFKKVNVSLPRTSNQQSKKGKKVEQ
                     KNLQAGDLVFFHNPVSHVGLYIGNGEFLHAPQKGDVVKISKLSSRRDFNTARRVL"
BASE COUNT          491 a          121 c          249 g          332 t
ORIGIN      
        1 attataaata ccaccttttc ggagagcatg gaaaatgtaa aaaataaagt aatagtggta
       61 gaccagtatg gaagcaagat tagcgaaaaa atagataatg aaatttttaa ggaagtaaat
      121 gtaataatgc aaaaagtaat tcagcaacaa gaaaatcaag atgtagatat tgatagcgag
      181 tttaatggga tagaaaaaag ctgttctctt aaaggttatg gagatgtaag ttgtataact
      241 ggtagaggag taaaagttaa agattcttat acaaagcttg taggactatt ttatatagat
      301 acagacaaac atacttggca aaatggagaa tatcaaattg agcttgaact taattttcaa
      361 aatcttatgg atgaaaagtc agcaggacag gatgaaccta aggaagaaag taacttaggg
      421 ggagaagatt atgcaggagg aaaagagttt acagcagaat ttacagctta ctgtcctaga
      481 aaagaagaag gtggagatac agattgtaga aagaaaaaac ttgacccatc taaaaaaact
      541 tgcgctgctc ctatggttgg taaatatgaa caaacttatt atacaaaaga gtttttaaat
      601 aaacatcctt tattaaacta tggagatgaa atacaggtaa ttacaggagt ttctggtcgt
      661 gatggagtct ataaagtaaa tgacgtagga cctgcaataa ctatagaaaa gaatggaaca
      721 taccatatag atattttatt tggaaatgtt gaagaagcta gtaaatttgg aagaagaaaa
      781 ggaaaaatta ttattggtgg ttattctggt aatgtatctg ataaagctaa aatagtaata
      841 tcagaagcaa aaaaacatct aggtaaacct tataaatggg gtggaaatgg accaagtagt
      901 tttgactgtt ctggtttaat ggtctattgt tttaaaaaag ttaatgttag tttgccaaga
      961 acgtcaaatc aacaatctaa aaaaggcaag aaagtagaac aaaaaaatct tcaagcagga
     1021 gatttagtat tttttcataa tccagtcagc catgttggat tatatatagg taatggagaa
     1081 tttttacatg ctccacaaaa aggtgatgta gttaaaataa gtaagttaag tagtagaaga
     1141 gattttaata cagctaggag agtattataa aaggatggtg atataatggc taa
//
LOCUS       DAYAOO010000207         1155 bp    DNA     linear   BCT 12-OCT-2024
DEFINITION  TPA_asm: Clostridioides difficile isolate ST8-SSI-h139-18
            SAMN40601845-rid21577343.denovo.212, whole genome shotgun sequence.
ACCESSION   DAYAOO010000207 DAYAOO010000000
VERSION     DAYAOO010000207.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN40601845
            Sequence Read Archive: SRR28438827
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 1155)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1155)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-MAY-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-MAY-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002157583.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002157583.1
            Genome Coverage       :: 163x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/11/2024 16:19:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 4,038
            CDSs (total)                      :: 3,963
            Genes (coding)                    :: 3,930
            CDSs (with protein)               :: 3,930
            Genes (RNA)                       :: 75
            rRNAs                             :: 6, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 60
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 33
            CDSs (without protein)            :: 33
            Pseudo Genes (ambiguous residues) :: 0 of 33
            Pseudo Genes (frameshifted)       :: 7 of 33
            Pseudo Genes (incomplete)         :: 25 of 33
            Pseudo Genes (internal stop)      :: 11 of 33
            Pseudo Genes (multiple problems)  :: 8 of 33
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1155
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN40601845-rid21577343.denovo.212"
                     /isolate="ST8-SSI-h139-18"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Denmark"
                     /collection_date="2018"
                     /collected_by="Statens Serum Institute"
     gene            188..535
                     /locus_tag="ACGI5H_003949"
     CDS             188..535
                     /locus_tag="ACGI5H_003949"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861374.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cupin domain-containing protein"
                     /protein_id="HFG9699606.1"
                     /translation="MHENKKNLLDGSLAQYNDTAVPKIPVFAGNDITSEVYYFKPNQV
                     LNAHRHPNGEQIFVFLKGEGKMKLGEHECDVKNGDTVFVPTGEWHEITNGSNEEMVAV
                     QITKINAGAEYRG"
     gene            complement(685..>1155)
                     /locus_tag="ACGI5H_003950"
     CDS             complement(685..>1155)
                     /locus_tag="ACGI5H_003950"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897038.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HFG9699607.1"
                     /translation="AFAGGEGDFTTAFEPTATAMEKEGSGYIVTSIGKDSGEIPFTAY
                     STTRSYMKNNKDLIQRFTNAVYKGQLWIQQASSKEVAKAMQPFFEDISLEDLTTVVDR
                     YKSIDAWSQNPVLKEEGLKKLMTVMKEAKELDKEAPYKDIVNTEFANNAIKNIK"
BASE COUNT          405 a          158 c          159 g          433 t
ORIGIN      
        1 tagaatttat tatattatgt taatttttta tatcttataa gaattgtatt tttctaacta
       61 taaaaatagt attatactta tatttaaaaa taaaagaatt ttattcctat tgtgtaaagt
      121 gagaatacta ttttcttata ttggtataat aatagtaaat ctaatataga aaagaggtat
      181 ttctagtatg catgaaaata aaaaaaatct attagacgga agcttagctc aatataatga
      241 tacagcagtt ccaaaaatac cagtatttgc tggtaacgat ataacttcag aagtttatta
      301 ttttaaacct aatcaagttc ttaatgctca tagacaccct aatggtgaac aaatatttgt
      361 gttcctaaaa ggagaaggta aaatgaaact tggtgagcat gaatgtgatg taaaaaacgg
      421 cgatactgta tttgtaccaa caggagagtg gcatgaaatt actaatggaa gcaatgaaga
      481 aatggtagcc gttcaaatta caaaaattaa tgctggagca gaatacagag gatagatata
      541 taagtacagt tagtacttta atatctattt tattatataa actttaatct caaatataaa
      601 aagagtcttt taaaaggctc tttttatatt tttgttaatt ttcattataa aaacaagaaa
      661 atatctagct aaaactaata tattttattt aatatttttt atagcattgt ttgcaaactc
      721 agtatttacg atatctttat aaggtgcttc cttatctagt tctttagctt ctttcataac
      781 agtcatcaat ttcttcaaac cttcctcttt taatacagga ttttgagacc atgcatctat
      841 tgatttatat ctatctacaa ctgttgttaa atcttctaaa gatatatctt caaagaaagg
      901 ttgcatagcc ttagctactt ctttgctaga tgcttgttga atccataatt gacctttata
      961 aacagcattt gtaaatcttt gaattaaatc tttattgttt ttcatgtatg atctcgtagt
     1021 agagtatgct gtaaaaggta tttctccaga atcttttcct atagatgtaa ctatatatcc
     1081 actaccttct ttttccattg ctgttgctgt aggttcaaat gctgttgtaa agtcaccctc
     1141 tccacctgca aaagc
//
LOCUS       DAYAOO010000208         1152 bp    DNA     linear   BCT 12-OCT-2024
DEFINITION  TPA_asm: Clostridioides difficile isolate ST8-SSI-h139-18
            SAMN40601845-rid21577343.denovo.213, whole genome shotgun sequence.
ACCESSION   DAYAOO010000208 DAYAOO010000000
VERSION     DAYAOO010000208.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN40601845
            Sequence Read Archive: SRR28438827
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 1152)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1152)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-MAY-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-MAY-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002157583.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002157583.1
            Genome Coverage       :: 163x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/11/2024 16:19:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 4,038
            CDSs (total)                      :: 3,963
            Genes (coding)                    :: 3,930
            CDSs (with protein)               :: 3,930
            Genes (RNA)                       :: 75
            rRNAs                             :: 6, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 60
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 33
            CDSs (without protein)            :: 33
            Pseudo Genes (ambiguous residues) :: 0 of 33
            Pseudo Genes (frameshifted)       :: 7 of 33
            Pseudo Genes (incomplete)         :: 25 of 33
            Pseudo Genes (internal stop)      :: 11 of 33
            Pseudo Genes (multiple problems)  :: 8 of 33
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1152
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN40601845-rid21577343.denovo.213"
                     /isolate="ST8-SSI-h139-18"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Denmark"
                     /collection_date="2018"
                     /collected_by="Statens Serum Institute"
     gene            266..970
                     /gene="cwlD"
                     /locus_tag="ACGI5H_003951"
     CDS             266..970
                     /gene="cwlD"
                     /locus_tag="ACGI5H_003951"
                     /EC_number="3.5.1.28"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860636.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008745 - N-acetylmuramoyl-L-alanine
                     amidase activity [Evidence IEA];
                     GO_process: GO:0030436 - asexual sporulation [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase CwlD"
                     /protein_id="HFG9699608.1"
                     /translation="MRKYIKHIIFSFAMICLVVVSIFEIKNISEDVIKYMPVTNKTII
                     LDAGHGGIDPGALNKDKSTSEKDINLAITLKLRELIESSGGLVILTREDDSSLYKEEN
                     NKTTRQKYNENLKNRKEIISNSNANMFVSIHLNAFEQSKYYGAQTFYPKDKQDSKELS
                     KCIQEELKRVVDKTNNREVKPRDDIYLLKENNIPSVLIECGFLSNEKECKLLTDETYQ
                     EKIAWAIYIGIQKYLS"
BASE COUNT          512 a          114 c          168 g          358 t
ORIGIN      
        1 tatattttaa gatattattt aacaatataa attctgaata tacgttatca aaatttataa
       61 tataaactaa gtataattta ttgtatagta ttgaatgtta gataaacata gtgaattaaa
      121 tagggacaga aatataatat cattacataa taatatatta ataccaataa ataaagatat
      181 atcaatatta aaaaaattta aatgtttgta ctaatatatg gaatattata gtgtttttat
      241 aagtatacat atacagggtg atgttgtgag aaagtacata aaacatataa tttttagttt
      301 tgcaatgata tgtctagtag tagtatccat atttgaaatt aaaaatattt ctgaagatgt
      361 tatcaagtat atgccagtaa caaacaaaac tataatttta gatgctggtc atggaggcat
      421 tgatccaggt gcattaaata aggataagag tacatctgaa aaggatatta acctagcaat
      481 aacacttaag cttagagagc ttatagaatc aagtggtggc cttgtaatat taactcgaga
      541 agatgacagt agcctttata aagaagaaaa taataaaact acaagacaaa aatataatga
      601 gaatttgaaa aatagaaaag aaataatatc taattctaat gccaatatgt ttgtctctat
      661 acatcttaat gcatttgaac aatcaaaata ctatggagct caaacttttt atcctaaaga
      721 caaacaagac agtaaagaat tatcgaagtg tattcaagaa gaacttaaaa gagtagtaga
      781 taagacaaac aacagagaag tcaaaccaag ggatgatata tatcttttga aagaaaataa
      841 tattccatca gtactgatag aatgtggttt tttatcaaat gaaaaagagt gtaaactctt
      901 aactgatgaa acatatcaag aaaaaatagc atgggcaatc tacataggaa tacaaaaata
      961 tttaagttga aataactata aaaataggtc taaatatgta aatagcttgt attaaagcag
     1021 ttaaaatgca ttaatatagg ctatttttat tttgacaaaa aaatatttaa aataaaagtt
     1081 aaaaagttgt tgacttagaa taatatagat gatattatat atgagtgccc aaaaggagca
     1141 ccaaaataag ac
//
LOCUS       DAYAOO010000209         1064 bp    DNA     linear   BCT 12-OCT-2024
DEFINITION  TPA_asm: Clostridioides difficile isolate ST8-SSI-h139-18
            SAMN40601845-rid21577343.denovo.214, whole genome shotgun sequence.
ACCESSION   DAYAOO010000209 DAYAOO010000000
VERSION     DAYAOO010000209.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN40601845
            Sequence Read Archive: SRR28438827
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 1064)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1064)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-MAY-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-MAY-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002157583.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002157583.1
            Genome Coverage       :: 163x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/11/2024 16:19:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 4,038
            CDSs (total)                      :: 3,963
            Genes (coding)                    :: 3,930
            CDSs (with protein)               :: 3,930
            Genes (RNA)                       :: 75
            rRNAs                             :: 6, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 60
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 33
            CDSs (without protein)            :: 33
            Pseudo Genes (ambiguous residues) :: 0 of 33
            Pseudo Genes (frameshifted)       :: 7 of 33
            Pseudo Genes (incomplete)         :: 25 of 33
            Pseudo Genes (internal stop)      :: 11 of 33
            Pseudo Genes (multiple problems)  :: 8 of 33
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1064
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN40601845-rid21577343.denovo.214"
                     /isolate="ST8-SSI-h139-18"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Denmark"
                     /collection_date="2018"
                     /collected_by="Statens Serum Institute"
     gene            417..884
                     /locus_tag="ACGI5H_003952"
     CDS             417..884
                     /locus_tag="ACGI5H_003952"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HFG9699609.1"
                     /translation="MKFLNVLVVVEDIEKSKKFYYDVLGLKVICDFGENVVLEGNISL
                     QEKKLWLEFINKSDSEVKFNGNDAELYFEEDNFDTFVERLSTMKDIDYVHLAIEHRWG
                     QRAIRFYDLDGHIIEVGETMSSVCRRFLDSGLSIDEVAKRMDVTVEYIESVLE"
BASE COUNT          414 a           71 c          169 g          410 t
ORIGIN      
        1 tatgaaaact aaattagaag aactaaaaac tatattttta ttaattataa tatttgaata
       61 atctttttaa tcatataaaa tgcatatact tgtaatattt aaaggtgata ttaatattat
      121 tagtgtatat taatattccc ttgaaattaa aaaaacatag atatttcagt aatctaaaat
      181 agtctacaaa aataacagtt ttagcaaaat taataagaat acatatagat ttaaacctaa
      241 aagtatgaac atgtctgttt tttacaagat taaaatttat attatatgat aaaattaact
      301 taactatttc aataagactt ataatttttt tctttatact agaccttatt gaaaccttta
      361 tagtttaatt ctaattatat attataaata aagtatgtgt atattaagga ggtaatatga
      421 agtttttaaa tgttttagta gtagttgaag atattgagaa atcaaaaaag ttttattatg
      481 atgttttggg gttaaaggta atctgtgatt ttggagaaaa tgttgtatta gaaggtaata
      541 tatcattaca agaaaaaaag ctttggttag aatttattaa taagagtgac agtgaagtta
      601 agttcaatgg aaatgatgct gagttatatt ttgaggaaga taattttgat acttttgttg
      661 aaagattgag tacaatgaaa gatatagatt atgttcatct agctatagag cataggtggg
      721 gtcaaagagc aattagattt tatgatttag atgggcatat tattgaggtt ggagaaacta
      781 tgtcatctgt gtgtagacgt tttttagata gtggtctttc aatagatgag gtagctaaaa
      841 gaatggatgt aactgtcgaa tatattgaat cagttttaga atagatggat tatattaaag
      901 taaaattgag gtgaaggctg taagtaaact tgtgtgaaaa caaatttgct tacagttttt
      961 atttttctaa aataaagaat ataatacttg tttagcttta tttgagtttt taaaaatatt
     1021 atgatatttc ttatatattt atactaaagt ttaaatttag aaaa
//
LOCUS       DAYAOO010000210         1056 bp    DNA     linear   BCT 12-OCT-2024
DEFINITION  TPA_asm: Clostridioides difficile isolate ST8-SSI-h139-18
            SAMN40601845-rid21577343.denovo.215, whole genome shotgun sequence.
ACCESSION   DAYAOO010000210 DAYAOO010000000
VERSION     DAYAOO010000210.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN40601845
            Sequence Read Archive: SRR28438827
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 1056)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1056)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-MAY-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-MAY-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002157583.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002157583.1
            Genome Coverage       :: 163x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/11/2024 16:19:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 4,038
            CDSs (total)                      :: 3,963
            Genes (coding)                    :: 3,930
            CDSs (with protein)               :: 3,930
            Genes (RNA)                       :: 75
            rRNAs                             :: 6, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 60
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 33
            CDSs (without protein)            :: 33
            Pseudo Genes (ambiguous residues) :: 0 of 33
            Pseudo Genes (frameshifted)       :: 7 of 33
            Pseudo Genes (incomplete)         :: 25 of 33
            Pseudo Genes (internal stop)      :: 11 of 33
            Pseudo Genes (multiple problems)  :: 8 of 33
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1056
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN40601845-rid21577343.denovo.215"
                     /isolate="ST8-SSI-h139-18"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Denmark"
                     /collection_date="2018"
                     /collected_by="Statens Serum Institute"
     gene            <1..915
                     /locus_tag="ACGI5H_003953"
     CDS             <1..915
                     /locus_tag="ACGI5H_003953"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018112542.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9699610.1"
                     /translation="KITLLQALPFLTVSSYNSITATFKADHTDPTLLTKIEYFIDDVL
                     KETITTDLTTEKTINYTLEDNALHTLKIVVTDSNNATAEKVLSISKNIMPLPEDVNLQ
                     DISSKLIEVNAGFKTGKTSIINTLALKNIEANLNNTLVELSEKIKTGFDSSDATAEQL
                     QNQITNLNNQLSQRKRWAKGTYTFTQSDYENFYSRYSSAENYAKSLTVPINLNFIPSL
                     VIVEKLCFYGNGYTVNFYAINNLNQLASVGRVPKSSGEYRFCAFMFVKTITSKEFSLY
                     TYRDEYTDSSSVVYRCKVGESFTWYAYE"
BASE COUNT          410 a          139 c          168 g          339 t
ORIGIN      
        1 aaaataacat tactacaagc attaccattt ttaacagtat cttcttataa ttccattaca
       61 gctacattta aagctgacca cacagaccct acattgctta caaaaataga atattttata
      121 gatgatgtgt taaaagaaac tataacaaca gatttaacaa cagagaaaac aattaactat
      181 acactagaag ataatgcact acacacactt aagatagttg ttacagacag taataatgct
      241 acagcagaaa aagtgttaag tataagtaag aatataatgc cattgcccga agatgtgaat
      301 ctgcaagaca tatcttctaa actaattgaa gttaatgcag gatttaaaac tggaaaaaca
      361 agtattataa acactttagc attaaaaaat atagaagcaa atttaaataa tacattagtt
      421 gaattatcag agaaaataaa aacaggtttt gatagttcag atgctactgc tgaacaactt
      481 caaaatcaga ttactaattt aaataatcag ttaagccaac gtaaaagatg ggctaagggt
      541 acttacactt ttactcaaag tgattatgaa aatttttatt caaggtattc aagtgctgaa
      601 aattatgcta agagtcttac tgttcctatt aatttaaatt tcatccctag tcttgtcatt
      661 gttgaaaaac tttgttttta tggaaatggg tatactgtta atttttatgc tattaataat
      721 ttaaatcaac ttgcttctgt tggtcgtgtt cctaagagta gtggagaata tcgtttttgt
      781 gcttttatgt ttgtaaaaac tattactagc aaagaatttt ctttatatac ttatcgagat
      841 gaatacactg atagtagtag cgtagtatac cgttgtaaag tcggagaaag ttttacatgg
      901 tatgcttatg aataatatga aaggtggtaa tttaaatgga aagaggaaat agaattatat
      961 gtgaccaaac cgggaaaata ttactccaaa ctggagaagc aacaggggat atattagaac
     1021 atgatgaaat aacggaatta cattttgttg atattc
//
LOCUS       DAYAOO010000211         1027 bp    DNA     linear   BCT 12-OCT-2024
DEFINITION  TPA_asm: Clostridioides difficile isolate ST8-SSI-h139-18
            SAMN40601845-rid21577343.denovo.216, whole genome shotgun sequence.
ACCESSION   DAYAOO010000211 DAYAOO010000000
VERSION     DAYAOO010000211.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN40601845
            Sequence Read Archive: SRR28438827
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 1027)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1027)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-MAY-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-MAY-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002157583.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002157583.1
            Genome Coverage       :: 163x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/11/2024 16:19:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 4,038
            CDSs (total)                      :: 3,963
            Genes (coding)                    :: 3,930
            CDSs (with protein)               :: 3,930
            Genes (RNA)                       :: 75
            rRNAs                             :: 6, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 60
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 33
            CDSs (without protein)            :: 33
            Pseudo Genes (ambiguous residues) :: 0 of 33
            Pseudo Genes (frameshifted)       :: 7 of 33
            Pseudo Genes (incomplete)         :: 25 of 33
            Pseudo Genes (internal stop)      :: 11 of 33
            Pseudo Genes (multiple problems)  :: 8 of 33
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1027
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN40601845-rid21577343.denovo.216"
                     /isolate="ST8-SSI-h139-18"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Denmark"
                     /collection_date="2018"
                     /collected_by="Statens Serum Institute"
     gene            complement(68..778)
                     /locus_tag="ACGI5H_003954"
     CDS             complement(68..778)
                     /locus_tag="ACGI5H_003954"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895627.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LytR/AlgR family response regulator
                     transcription factor"
                     /protein_id="HFG9699611.1"
                     /translation="MTSICICDDEKQQRNMLNKIITREMDLWGYPYQIKEYSNGESLV
                     YNLEHENYYIDIIFLDIELGKSNGVDIAKTIRKHSKDTIIIFVTGFSDYVFHGYDVGA
                     LNYILKPYKTEKICKVLKEALKKLEQWKENFITVQIGTNLCKINTKDILYFKSELRKL
                     TVVTFDKTLEYYGKLNDMETVLPSNFIRTHQRYIVNLNHVDSITQTYAKVQNEKIPIS
                     RKKYQEVVGKFTRYMLES"
BASE COUNT          347 a          140 c          114 g          426 t
ORIGIN      
        1 actctaaaaa ctaagcttta aaaagttaag tttcaaaaat aaaattctag agattgaact
       61 tcaaaaatta agattctaac atataccttg taaattttcc tacaacctct tgatattttt
      121 tacggcttat aggaattttt tcattctgaa ctttggcata agtttgagtt atactatcta
      181 catggtttag attgacaata tacctttgat gcgtacgtat aaaattagag ggaagaacag
      241 tttccatatc atttaatttt ccgtagtatt ctaatgtttt atcaaaggta actacagtta
      301 attttcttag ctcactttta aagtagagga tatcttttgt attaatttta caaagattag
      361 ttccaatctg aactgtaata aagttttctt tccattgttc taattttttt agtgcttctt
      421 ttaatacttt acatattttt tcagttttat aaggttttaa gatgtagttc aaagctccta
      481 catcatatcc atgaaataca tagtcagaaa aacctgtgac aaagatgatt atagtatctt
      541 ttgaatgttt tcgtatagtt tttgctatgt caacgccatt actttttcca agttcaatat
      601 ctaaaaaaat aatatctatg taataatttt cgtgttctag attgtatact agactttctc
      661 catttgaata ttcttttatt tggtaggggt agccccacaa atccatttct cttgtaatga
      721 ttttattcag catgtttctt tgttgttttt catcatcaca aatacaaatc gaagtcaatt
      781 ttttatctcc tttcaagttt tatatttata tagttaagta tataatatat tttgctacct
      841 agatatataa aatgaaataa caattatatc cagatagcaa aataaaattt tttatattag
      901 tatacttaca cttaaaacta ttctattaaa cttattctga agtgctaatg attttcttat
      961 taaaaaatct aacaatcttt cttattataa aatacaaatg cttttattat tataaaaagt
     1021 aatgatt
//
LOCUS       DAYAOO010000212          880 bp    DNA     linear   BCT 12-OCT-2024
DEFINITION  TPA_asm: Clostridioides difficile isolate ST8-SSI-h139-18
            SAMN40601845-rid21577343.denovo.217, whole genome shotgun sequence.
ACCESSION   DAYAOO010000212 DAYAOO010000000
VERSION     DAYAOO010000212.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN40601845
            Sequence Read Archive: SRR28438827
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 880)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 880)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-MAY-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-MAY-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002157583.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002157583.1
            Genome Coverage       :: 163x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/11/2024 16:19:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 4,038
            CDSs (total)                      :: 3,963
            Genes (coding)                    :: 3,930
            CDSs (with protein)               :: 3,930
            Genes (RNA)                       :: 75
            rRNAs                             :: 6, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 60
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 33
            CDSs (without protein)            :: 33
            Pseudo Genes (ambiguous residues) :: 0 of 33
            Pseudo Genes (frameshifted)       :: 7 of 33
            Pseudo Genes (incomplete)         :: 25 of 33
            Pseudo Genes (internal stop)      :: 11 of 33
            Pseudo Genes (multiple problems)  :: 8 of 33
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..880
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN40601845-rid21577343.denovo.217"
                     /isolate="ST8-SSI-h139-18"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Denmark"
                     /collection_date="2018"
                     /collected_by="Statens Serum Institute"
     gene            <1..>880
                     /locus_tag="ACGI5H_003955"
     CDS             <1..>880
                     /locus_tag="ACGI5H_003955"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888399.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-guided endonuclease TnpB family protein"
                     /protein_id="HFG9699612.1"
                     /translation="VYKNNKETFTYKQCSSDLTNLKKELKWLKEPDKFSLQNALKDLD
                     NAYKKFFKEKAGFPKFKSKKINRFSYKTNFTNGNIMYCGQYIKLPKLGMVKVRDKQVP
                     QGRILNATISKEPSGRYYVSLCCTNVDIEVFENTNNQIGLDLGIKEFCISSCGDFIEN
                     PKYLKKSLNKLAKLQRELSRKTIGSLNRNKARLKVARLQEHIANQRNDFLQKLSTKLI
                     KENDIICIEDLQVKNMIRNRKLSRLISDVSWSEFVRQLKYKANWHGRQIVKVGKFFAS
                     SQICNKCGYKNEEMKDL"
BASE COUNT          379 a           97 c          136 g          268 t
ORIGIN      
        1 gtttataaaa acaataaaga aacttttact tataaacagt gtagttctga tttaaccaat
       61 ttaaaaaaag aattaaaatg gcttaaggaa cctgacaaat tttcactaca aaacgcctta
      121 aaagatttag ataatgcata taaaaaattc tttaaagaaa aagcaggatt tcctaaattt
      181 aaatcaaaga aaattaatag attttcatat aaaactaact ttacaaatgg aaacattatg
      241 tattgtggtc aatatataaa actacctaaa cttggtatgg ttaaggtaag ggataaacaa
      301 gtacctcaag gtagaatact taatgctact atatctaaag aaccaagtgg tagatattat
      361 gtatcattat gctgtactaa tgtagatatt gaagtatttg aaaatactaa taatcagata
      421 ggtttagatt taggaattaa agaattttgt atctcaagtt gtggagactt tatagaaaat
      481 cctaagtatc ttaagaagtc attaaacaaa cttgctaaat tacaaagaga attatcgaga
      541 aagacaatcg gtagtttaaa tagaaataaa gcaagattaa aagttgcaag acttcaagaa
      601 catatagcta atcaaagaaa tgattttcta caaaaactat ctactaaatt aataaaagag
      661 aatgatatta tttgcataga agatttacaa gtaaagaata tgattagaaa tcgtaaacta
      721 tctcgcttaa tttctgatgt gtcatggtca gaatttgttc gtcaattaaa atacaaggct
      781 aattggcatg gtagacaaat tgtaaaggta ggtaaattct ttgcaagttc acaaatatgc
      841 aataaatgtg ggtataaaaa cgaggaaatg aaggacttaa
//
LOCUS       DAYAOO010000213          870 bp    DNA     linear   BCT 12-OCT-2024
DEFINITION  TPA_asm: Clostridioides difficile isolate ST8-SSI-h139-18
            SAMN40601845-rid21577343.denovo.218, whole genome shotgun sequence.
ACCESSION   DAYAOO010000213 DAYAOO010000000
VERSION     DAYAOO010000213.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN40601845
            Sequence Read Archive: SRR28438827
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 870)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 870)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-MAY-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-MAY-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002157583.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002157583.1
            Genome Coverage       :: 163x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/11/2024 16:19:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 4,038
            CDSs (total)                      :: 3,963
            Genes (coding)                    :: 3,930
            CDSs (with protein)               :: 3,930
            Genes (RNA)                       :: 75
            rRNAs                             :: 6, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 60
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 33
            CDSs (without protein)            :: 33
            Pseudo Genes (ambiguous residues) :: 0 of 33
            Pseudo Genes (frameshifted)       :: 7 of 33
            Pseudo Genes (incomplete)         :: 25 of 33
            Pseudo Genes (internal stop)      :: 11 of 33
            Pseudo Genes (multiple problems)  :: 8 of 33
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..870
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN40601845-rid21577343.denovo.218"
                     /isolate="ST8-SSI-h139-18"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Denmark"
                     /collection_date="2018"
                     /collected_by="Statens Serum Institute"
     gene            complement(143..>870)
                     /locus_tag="ACGI5H_003956"
     CDS             complement(143..>870)
                     /locus_tag="ACGI5H_003956"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860734.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="collagen-like protein"
                     /protein_id="HFG9699613.1"
                     /translation="PTGNTGVTGEIGPTGATGPTGNTGVTGEIGPTGATGPTGVTGEI
                     GPTGNTGATGSIGPTGVTGPTGATGSIGPTGATGATGVTGPTGPTGATGNSSQPVANF
                     LVNAPSPQTLNNGDAITGWQTIIGNSSSITVDANGTFTVQENGVYYISVSVALQPGSS
                     SINQYSFAILFPILGGKDLAGLTTEPGGGGVLSGYFAGFLFGGTTFTINNFSSTTVGI
                     RNGQSAGTAATLTIFRIADTVMT"
BASE COUNT          212 a          193 c          144 g          321 t
ORIGIN      
        1 ccataaattt aaaattttta tgaatatatt ttattattat tgttatttta ttcattctaa
       61 aataggtaaa actcaatata taaaaatact tttgtcattt aaataaagcc taaatagttt
      121 ttaagattat tttagacacg ttttaagtca taacagtatc agctattcta aatatcgtca
      181 aagtagccgc agttcctgct gattgcccat ttcgtatccc tactgttgta gatgaaaaat
      241 tatttattgt aaaagtagtc ccaccaaata aaaaaccagc aaaatatcca gaaagtactc
      301 ctccgcctcc tggctcagta gtaagccctg ccaaatcttt tcctcctaaa attgggaata
      361 ggatagcgaa agaatattga tttatacttg atgaacctgg ttgtaatgct actgaaactg
      421 atatataata cacaccattt tcttgtactg taaacgtacc atttgcatct actgttatac
      481 ttgaactatt tcctattatt gtttgccaac ctgttatagc atctccatta tttagtgttt
      541 gtggagatgg tgcatttacg aggaagttag caactggctg agaggaattg cctgttgctc
      601 ctgttggacc tgttgggcct gttactcctg tcgctcctgt tgctcccgtt ggtcctatac
      661 ttcctgtcgc tcctgttgga cctgttactc ccgttggccc tatacttcct gtcgctcctg
      721 tatttcctgt tggccctatt tctcctgtca ctcctgttgg gcctgttgct cccgttggtc
      781 ctatttctcc tgtcactcct gtatttcctg tcggacccgt tgctcccgtt ggtcctattt
      841 ctcctgttac tcctgtattt cctgttggac
//
LOCUS       DAYAOO010000214          832 bp    DNA     linear   BCT 12-OCT-2024
DEFINITION  TPA_asm: Clostridioides difficile isolate ST8-SSI-h139-18
            SAMN40601845-rid21577343.denovo.219, whole genome shotgun sequence.
ACCESSION   DAYAOO010000214 DAYAOO010000000
VERSION     DAYAOO010000214.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN40601845
            Sequence Read Archive: SRR28438827
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 832)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 832)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-MAY-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-MAY-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002157583.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002157583.1
            Genome Coverage       :: 163x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/11/2024 16:19:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 4,038
            CDSs (total)                      :: 3,963
            Genes (coding)                    :: 3,930
            CDSs (with protein)               :: 3,930
            Genes (RNA)                       :: 75
            rRNAs                             :: 6, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 60
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 33
            CDSs (without protein)            :: 33
            Pseudo Genes (ambiguous residues) :: 0 of 33
            Pseudo Genes (frameshifted)       :: 7 of 33
            Pseudo Genes (incomplete)         :: 25 of 33
            Pseudo Genes (internal stop)      :: 11 of 33
            Pseudo Genes (multiple problems)  :: 8 of 33
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..832
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN40601845-rid21577343.denovo.219"
                     /isolate="ST8-SSI-h139-18"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Denmark"
                     /collection_date="2018"
                     /collected_by="Statens Serum Institute"
     gene            119..235
                     /gene="rrf"
                     /locus_tag="ACGI5H_003957"
     rRNA            119..235
                     /gene="rrf"
                     /locus_tag="ACGI5H_003957"
                     /product="5S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00001"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00001"
     gene            242..316
                     /locus_tag="ACGI5H_003958"
     tRNA            242..316
                     /locus_tag="ACGI5H_003958"
                     /product="tRNA-Asn"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:274..276,aa:Asn,seq:gtt)
     gene            321..395
                     /locus_tag="ACGI5H_003959"
     tRNA            321..395
                     /locus_tag="ACGI5H_003959"
                     /product="tRNA-Glu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:354..356,aa:Glu,seq:ttc)
     gene            401..476
                     /locus_tag="ACGI5H_003960"
     tRNA            401..476
                     /locus_tag="ACGI5H_003960"
                     /product="tRNA-Val"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:434..436,aa:Val,seq:tac)
     gene            482..558
                     /locus_tag="ACGI5H_003961"
     tRNA            482..558
                     /locus_tag="ACGI5H_003961"
                     /product="tRNA-Asp"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:516..518,aa:Asp,seq:gtc)
     gene            569..643
                     /locus_tag="ACGI5H_003962"
     tRNA            569..643
                     /locus_tag="ACGI5H_003962"
                     /product="tRNA-Thr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:601..603,aa:Thr,seq:tgt)
     gene            658..742
                     /locus_tag="ACGI5H_003963"
     tRNA            658..742
                     /locus_tag="ACGI5H_003963"
                     /product="tRNA-Tyr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:692..694,aa:Tyr,seq:gta)
     gene            752..825
                     /locus_tag="ACGI5H_003964"
     tRNA            752..825
                     /locus_tag="ACGI5H_003964"
                     /product="tRNA-Gly"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:784..786,aa:Gly,seq:tcc)
BASE COUNT          226 a          187 c          213 g          206 t
ORIGIN      
        1 attcattaag atatatgtgc agtttttaga gtgttaactc taaaaaaaaa taaaaaaagt
       61 attgacaaaa atagtaaaaa atgttaatat tatacttgtc ctagcaacaa gaaaaaaatg
      121 tggttataat agcggagaag atacacctgt ttccattccg aacacagaag ttaagttctc
      181 tagcgctgat ggtacttggt gggaaactgc ctgggagagt aggacatagc cacgtgaatg
      241 ttccaaggta gctcaacggt ggagcaaccg gctgttaacc ggtaggctgt gggttcgagc
      301 cccacccttg gagccattat ggctcgttgg tcaagaggtt aagacaccgc cctttcacgg
      361 cggtaacagg ggttcaattc ccctacgagt caccatttgt gggatcatag ctcagctggg
      421 agagcacctg ccttacaagc agggggtcac aggttcgagc cctgttggtc ccaccatttg
      481 cggcctggta gttcagttgg ttagaatgcc agcctgtcac gctggaggtc gagggttcga
      541 gccccttcca ggtcgccaaa ataaaaatgc tggtgtggct caacggtaga gcagctgact
      601 tgtaatcagc aggttgtagg ttcgattcct atcaccagct ccatgtaaaa ctaatacgga
      661 ggatttcccg agcggccaaa gggggcagac tgtaaatctg ttgtcatcga cttcggtggt
      721 tcgaatccac catcctccac caattaaata tgcgggtgta gctcaatggt agagttctgg
      781 ccttccaagc cagctgtgag ggttcgatcc ccttcacccg ctccaaagaa ag
//
LOCUS       DAYAOO010000215          787 bp    DNA     linear   BCT 12-OCT-2024
DEFINITION  TPA_asm: Clostridioides difficile isolate ST8-SSI-h139-18
            SAMN40601845-rid21577343.denovo.220, whole genome shotgun sequence.
ACCESSION   DAYAOO010000215 DAYAOO010000000
VERSION     DAYAOO010000215.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN40601845
            Sequence Read Archive: SRR28438827
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 787)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 787)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-MAY-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-MAY-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002157583.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002157583.1
            Genome Coverage       :: 163x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/11/2024 16:19:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 4,038
            CDSs (total)                      :: 3,963
            Genes (coding)                    :: 3,930
            CDSs (with protein)               :: 3,930
            Genes (RNA)                       :: 75
            rRNAs                             :: 6, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 60
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 33
            CDSs (without protein)            :: 33
            Pseudo Genes (ambiguous residues) :: 0 of 33
            Pseudo Genes (frameshifted)       :: 7 of 33
            Pseudo Genes (incomplete)         :: 25 of 33
            Pseudo Genes (internal stop)      :: 11 of 33
            Pseudo Genes (multiple problems)  :: 8 of 33
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..787
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN40601845-rid21577343.denovo.220"
                     /isolate="ST8-SSI-h139-18"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Denmark"
                     /collection_date="2018"
                     /collected_by="Statens Serum Institute"
     gene            complement(<1..>787)
                     /locus_tag="ACGI5H_003965"
     rRNA            complement(<1..>787)
                     /locus_tag="ACGI5H_003965"
                     /product="23S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF02541"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF02541"
BASE COUNT          172 a          238 c          182 g          195 t
ORIGIN      
        1 cgtccatccc ggtcctctcg tactaaggac aggtcttctc aaatttccta cgcctgcgac
       61 ggatagggac cgaactgtct cacgacgttc tgaacccagc tcgcgtacca ctttaatggg
      121 cgaacagccc aacccttggg acctactaca gccccaggat gtgatgagcc gacatcgagg
      181 tgccaaacct ccccgtcgat gtggactctt gggggagata agcctgttat ccccagggta
      241 gcttttatcc gttgagcgat ggcccttcca cgcagaacca ccggatcact aagtccgatt
      301 ttcatccttg ctcgacctgt atgtcttgca atcaagctct cttttgcctt tacactctac
      361 gtacgatttc cgaccgtact gagagaacct ttgagcgcct ccgttacctt ttgggaggcg
      421 accgccccag tcaaactgcc cacctgacag tgtcccaaga ccagattcat ggcctatggt
      481 tagagtccca gtactacaag ggtggtatcc caaggatggc tccgccaaaa ctggcgtcct
      541 ggtttcaaag cctcccacct atcctgtaca tgtagtacca agacccaatg tcaagctaca
      601 gtaaagctcc atggggtctt tccgtcctgt cgcaggtatc cggcatcttc accggaatta
      661 caatttcacc gagtctgttg ttgagacagt gcccaaatcg ttacgccttt cgtgcgggtc
      721 ggaacttacc cgacaaggaa tttcgctacc ttaggaccgt tatagttacg gccgccgttt
      781 actgggg
//
LOCUS       DAYAOO010000216          785 bp    DNA     linear   BCT 12-OCT-2024
DEFINITION  TPA_asm: Clostridioides difficile isolate ST8-SSI-h139-18
            SAMN40601845-rid21577343.denovo.221, whole genome shotgun sequence.
ACCESSION   DAYAOO010000216 DAYAOO010000000
VERSION     DAYAOO010000216.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN40601845
            Sequence Read Archive: SRR28438827
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 785)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 785)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-MAY-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-MAY-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002157583.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002157583.1
            Genome Coverage       :: 163x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/11/2024 16:19:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 4,038
            CDSs (total)                      :: 3,963
            Genes (coding)                    :: 3,930
            CDSs (with protein)               :: 3,930
            Genes (RNA)                       :: 75
            rRNAs                             :: 6, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 60
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 33
            CDSs (without protein)            :: 33
            Pseudo Genes (ambiguous residues) :: 0 of 33
            Pseudo Genes (frameshifted)       :: 7 of 33
            Pseudo Genes (incomplete)         :: 25 of 33
            Pseudo Genes (internal stop)      :: 11 of 33
            Pseudo Genes (multiple problems)  :: 8 of 33
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..785
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN40601845-rid21577343.denovo.221"
                     /isolate="ST8-SSI-h139-18"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Denmark"
                     /collection_date="2018"
                     /collected_by="Statens Serum Institute"
     gene            229..>785
                     /locus_tag="ACGI5H_003966"
     CDS             229..>785
                     /locus_tag="ACGI5H_003966"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897038.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HFG9699614.1"
                     /translation="MFKKIVAIASSIIVSTICLTGCDFNSNDKKGESSSSKNLDKVTI
                     AEVTHSVFYAPQYAAITKGFFEDEGIKIDLINTQGADKTMAALISGEANVGLMGPEAS
                     IYVYNQNKNDYAVNFAQLTKRDGSFLVARKKMPNFSYNDLKGTEILGGRKGGVPLMTF
                     EYVLKEKGLTIGENLKAGNVNVRTDV"
BASE COUNT          303 a           95 c          126 g          261 t
ORIGIN      
        1 tatatataat agacaaaaaa gtgatattat tttaatttta ttacttagtt tataaataat
       61 caatataatt tatccaatat tacacattac tgaaaaaact aaacataaag ctgaaaatta
      121 ttattaagtt tttgtagaaa tattataagc atagatacat ttttgtaaca actacaataa
      181 atttttaata ctatatacta ttcgtatgtc ttatgggagg tatttattat gtttaaaaaa
      241 atagtcgcaa tagcaagctc tatcattgta agtacaatat gtctaactgg atgtgatttt
      301 aactctaatg acaaaaaagg tgaatcttct tcgtctaaaa atctggataa agtaactata
      361 gcagaagtta ctcactctgt tttttatgct ccacagtatg ctgctattac gaaaggattc
      421 tttgaagatg aaggtataaa gattgacctt ataaataccc aaggtgcaga taaaactatg
      481 gcagctttga tttcaggtga agcaaacgta ggtttaatgg gtcctgaagc atctatatat
      541 gtatataatc aaaacaaaaa cgattatgca gtgaactttg ctcaattgac aaaaagagat
      601 ggtagttttc tagttgctag gaaaaaaatg cctaatttct cttacaatga tttaaaagga
      661 accgaaatat taggtggtag aaaaggtgga gttccactaa tgacttttga atatgttcta
      721 aaagaaaaag gtcttactat tggagaaaat ctaaaagcag gcaatgttaa tgtaagaact
      781 gatgt
//
LOCUS       DAYAOO010000217          753 bp    DNA     linear   BCT 12-OCT-2024
DEFINITION  TPA_asm: Clostridioides difficile isolate ST8-SSI-h139-18
            SAMN40601845-rid21577343.denovo.222, whole genome shotgun sequence.
ACCESSION   DAYAOO010000217 DAYAOO010000000
VERSION     DAYAOO010000217.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN40601845
            Sequence Read Archive: SRR28438827
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 753)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 753)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-MAY-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-MAY-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002157583.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002157583.1
            Genome Coverage       :: 163x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/11/2024 16:19:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 4,038
            CDSs (total)                      :: 3,963
            Genes (coding)                    :: 3,930
            CDSs (with protein)               :: 3,930
            Genes (RNA)                       :: 75
            rRNAs                             :: 6, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 60
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 33
            CDSs (without protein)            :: 33
            Pseudo Genes (ambiguous residues) :: 0 of 33
            Pseudo Genes (frameshifted)       :: 7 of 33
            Pseudo Genes (incomplete)         :: 25 of 33
            Pseudo Genes (internal stop)      :: 11 of 33
            Pseudo Genes (multiple problems)  :: 8 of 33
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..753
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN40601845-rid21577343.denovo.222"
                     /isolate="ST8-SSI-h139-18"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Denmark"
                     /collection_date="2018"
                     /collected_by="Statens Serum Institute"
     gene            <1..>753
                     /locus_tag="ACGI5H_003967"
     rRNA            <1..>753
                     /locus_tag="ACGI5H_003967"
                     /product="23S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF02541"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF02541"
BASE COUNT          207 a          156 c          227 g          163 t
ORIGIN      
        1 tttaactgag cgttcagtta cttgacgtag acccgaaacc gggcgaccta cccatgagca
       61 ggatgaagcg aaagtaaaat ttcgtggagg tccgaaccca cgagcgttga aaagctcggg
      121 gatgacttgt gggtagcggt gaaattccaa tcgagcccgg agatagctgg ttctccccga
      181 aatagcttta gggctagcct caaggtgaga gatacggagg tagagcactg aatgtcctag
      241 ggggtattgc acctaccgaa gactatcaaa ctccgaatgc cgtcatctta tacttgggag
      301 tcagactgtg ggtgataaga ttcatagtcg aaagggcaac agcccagatc gtcagctaag
      361 gtccctaaat gtaagttaag tggtaaagga tgtgggattg cacagacaac caggatgttg
      421 gcttagaagc agccactcat tcaaagagtg cgtaatagct cactggtcga gtgatcctgc
      481 gccgaagatt tccggggcta aaacttacta ccgaagctac ggcatcagta atgatgggta
      541 ggggagcttc ccatacgggt tgaagcatga ccgtaaggac atgtggacag tatgggagtg
      601 agaatgttgg catgagtagc gagatgtggg tgagaatccc acaggccgta aacccaaggt
      661 ttccagggga aggttcgtcc gccctgggtt agtcgggacc taagctgagg ccgaaaggcg
      721 taggtgatgg acaacaggtt gatattcctg tac
//
LOCUS       DAYAOO010000218          747 bp    DNA     linear   BCT 12-OCT-2024
DEFINITION  TPA_asm: Clostridioides difficile isolate ST8-SSI-h139-18
            SAMN40601845-rid21577343.denovo.223, whole genome shotgun sequence.
ACCESSION   DAYAOO010000218 DAYAOO010000000
VERSION     DAYAOO010000218.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN40601845
            Sequence Read Archive: SRR28438827
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 747)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 747)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-MAY-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-MAY-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002157583.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002157583.1
            Genome Coverage       :: 163x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/11/2024 16:19:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 4,038
            CDSs (total)                      :: 3,963
            Genes (coding)                    :: 3,930
            CDSs (with protein)               :: 3,930
            Genes (RNA)                       :: 75
            rRNAs                             :: 6, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 60
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 33
            CDSs (without protein)            :: 33
            Pseudo Genes (ambiguous residues) :: 0 of 33
            Pseudo Genes (frameshifted)       :: 7 of 33
            Pseudo Genes (incomplete)         :: 25 of 33
            Pseudo Genes (internal stop)      :: 11 of 33
            Pseudo Genes (multiple problems)  :: 8 of 33
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..747
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN40601845-rid21577343.denovo.223"
                     /isolate="ST8-SSI-h139-18"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Denmark"
                     /collection_date="2018"
                     /collected_by="Statens Serum Institute"
     gene            15..105
                     /locus_tag="ACGI5H_003968"
     tRNA            15..105
                     /locus_tag="ACGI5H_003968"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:49..51,aa:Ser,seq:gct)
     gene            114..190
                     /locus_tag="ACGI5H_003969"
     tRNA            114..190
                     /locus_tag="ACGI5H_003969"
                     /product="tRNA-Pro"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:148..150,aa:Pro,seq:tgg)
     gene            276..351
                     /locus_tag="ACGI5H_003970"
     tRNA            276..351
                     /locus_tag="ACGI5H_003970"
                     /product="tRNA-Trp"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:309..311,aa:Trp,seq:cca)
     gene            412..488
                     /locus_tag="ACGI5H_003971"
     tRNA            412..488
                     /locus_tag="ACGI5H_003971"
                     /product="tRNA-Pro"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:446..448,aa:Pro,seq:tgg)
     gene            495..571
                     /locus_tag="ACGI5H_003972"
     tRNA            495..571
                     /locus_tag="ACGI5H_003972"
                     /product="tRNA-Ile"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:529..531,aa:Ile,seq:gat)
     gene            575..650
                     /locus_tag="ACGI5H_003973"
     tRNA            575..650
                     /locus_tag="ACGI5H_003973"
                     /product="tRNA-Phe"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:608..610,aa:Phe,seq:gaa)
     gene            658..734
                     /locus_tag="ACGI5H_003974"
     tRNA            658..734
                     /locus_tag="ACGI5H_003974"
                     /product="tRNA-Met"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:692..694,aa:Met,seq:cat)
BASE COUNT          176 a          171 c          215 g          185 t
ORIGIN      
        1 aaatgactga atttggagaa gtactcaagt ggctcaagag gatcccctgc taagggatta
       61 ggctgggtaa ccggtgcgag ggttcgaatc cctccttctc cgccattcaa aaacgaggtg
      121 tagcgcagtt tggtagcgca catggtttgg gaccatgggg ccgggggttc gagtcccttc
      181 acctcgacca acttaagctt ttagttcagt tggttagagt gcccaactca tggctagtaa
      241 ttctagggtt tgagtccatg aaggttattc ttcatagggg tgtagctcag ttggtagagc
      301 gtcggtctcc aaaaccgtgc gccgggggtt cgagtccctc cacccctgcc aaataaaaag
      361 gacttgaaaa aagttggatt ttagagtagt ataagatagt aaataagatt tcgaggtgta
      421 gcgcagtttg gtagcgcaca tggtttggga ccatggggcc gggggttcga gtcccttcac
      481 ctcgaccaag aaaagggcct atagctcagg tggttagagc gcacgcctga taagcgtgag
      541 gtcgctggtt cgagtccagc taggcccacc atttgcccag atagctcagt cggtagagca
      601 ggggactgaa aatccccgtg tcggtggttc gattccgcct ctgggcacca ggaatacggc
      661 ggtatagctt agttggctag agcgttcggt tcatacccga aaggtcatag gttcgactcc
      721 tattaccgct accatctaac tatatca
//
LOCUS       DAYAOO010000219          664 bp    DNA     linear   BCT 12-OCT-2024
DEFINITION  TPA_asm: Clostridioides difficile isolate ST8-SSI-h139-18
            SAMN40601845-rid21577343.denovo.224, whole genome shotgun sequence.
ACCESSION   DAYAOO010000219 DAYAOO010000000
VERSION     DAYAOO010000219.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN40601845
            Sequence Read Archive: SRR28438827
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 664)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 664)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-MAY-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-MAY-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002157583.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002157583.1
            Genome Coverage       :: 163x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/11/2024 16:19:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 4,038
            CDSs (total)                      :: 3,963
            Genes (coding)                    :: 3,930
            CDSs (with protein)               :: 3,930
            Genes (RNA)                       :: 75
            rRNAs                             :: 6, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 60
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 33
            CDSs (without protein)            :: 33
            Pseudo Genes (ambiguous residues) :: 0 of 33
            Pseudo Genes (frameshifted)       :: 7 of 33
            Pseudo Genes (incomplete)         :: 25 of 33
            Pseudo Genes (internal stop)      :: 11 of 33
            Pseudo Genes (multiple problems)  :: 8 of 33
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..664
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN40601845-rid21577343.denovo.224"
                     /isolate="ST8-SSI-h139-18"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Denmark"
                     /collection_date="2018"
                     /collected_by="Statens Serum Institute"
     gene            complement(<1..>664)
                     /locus_tag="ACGI5H_003975"
     rRNA            complement(<1..>664)
                     /locus_tag="ACGI5H_003975"
                     /product="16S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00177"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00177"
BASE COUNT          152 a          191 c          151 g          170 t
ORIGIN      
        1 gatccagccg caccttccga tacggctacc ttgttacgac ttcaccccag ttattgattc
       61 caccttcgac gacttcttcc aaaaggttag ataatcggct tcgggcgtct ccaactcccg
      121 tggtgtgacg ggcggtgtgt acaagacccg ggaacgcatt caccgcagca ttctgatctg
      181 cgattactag taactccagc ttcatgtagg cgagtttcag cctacaatcc gaactgagag
      241 tagctttaag ggattagctc caccttacgg cttggcaacc ctctgtacta cccattgtag
      301 cacgtgtgta gccctaagca taaggggcat gatgatttga cgtcatcccc accttcctcc
      361 aggttatccc tggcagtctc tctagagtgc ccaacttaat gatggcaact aaagacaagg
      421 gttgcgctcg ttgcgggact taacccaaca tctcacgaca cgagctgacg acaaccatgc
      481 accacctgtc accaatgtcc ccgaagggaa ctctccgatt aaggagatgt cattgggatg
      541 tcaagcttag gtaaggttct tcgcgttgct tcgaattaaa ccacatgctc cgctacttgt
      601 gcgggtcccc gtcaattcct ttgagtttca ctcttgcgag cgtacttccc aggcggagta
      661 ctta
//
LOCUS       DAYAOO010000220          645 bp    DNA     linear   BCT 12-OCT-2024
DEFINITION  TPA_asm: Clostridioides difficile isolate ST8-SSI-h139-18
            SAMN40601845-rid21577343.denovo.225, whole genome shotgun sequence.
ACCESSION   DAYAOO010000220 DAYAOO010000000
VERSION     DAYAOO010000220.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN40601845
            Sequence Read Archive: SRR28438827
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 645)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 645)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-MAY-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-MAY-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002157583.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002157583.1
            Genome Coverage       :: 163x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/11/2024 16:19:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 4,038
            CDSs (total)                      :: 3,963
            Genes (coding)                    :: 3,930
            CDSs (with protein)               :: 3,930
            Genes (RNA)                       :: 75
            rRNAs                             :: 6, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 60
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 33
            CDSs (without protein)            :: 33
            Pseudo Genes (ambiguous residues) :: 0 of 33
            Pseudo Genes (frameshifted)       :: 7 of 33
            Pseudo Genes (incomplete)         :: 25 of 33
            Pseudo Genes (internal stop)      :: 11 of 33
            Pseudo Genes (multiple problems)  :: 8 of 33
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..645
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN40601845-rid21577343.denovo.225"
                     /isolate="ST8-SSI-h139-18"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Denmark"
                     /collection_date="2018"
                     /collected_by="Statens Serum Institute"
     gene            complement(88..>645)
                     /gene="bclA2"
                     /locus_tag="ACGI5H_003976"
     CDS             complement(88..>645)
                     /gene="bclA2"
                     /locus_tag="ACGI5H_003976"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861885.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="collagen-like exosporium glycoprotein BclA2"
                     /protein_id="HFG9699615.1"
                     /translation="GAVGATGANGVAGAIGPTGPTGANGATGATGATGATGANGATGP
                     TGATGATGVLAANNAQFTVSSSSLVNNTLVTFNSSFINGTNITFPTSSTINLAVGGIY
                     NVSFGIRATLSLAGFMSITTNFNGVAQNNFIAKAVNTLTSSDVSVSLSFLVDARAAAV
                     TLSFTFGSGTTGTSAAGYVSVYRIQ"
BASE COUNT          178 a          136 c          103 g          228 t
ORIGIN      
        1 catcatataa acctattaaa tattattcta tttattggta tatgaaatca tattgtttat
       61 tattttataa tcttttcatc atataaacta ttgtattcta taaactgata catatccagc
      121 tgcagaagta cctgtcgtgc ctgaaccaaa tgtaaaactt aaagtaacag ctgctgctct
      181 agcatcaact aaaaagctta aacttacact tacatctgat gaagtaagtg tatttactgc
      241 ttttgcaata aagttatttt gagctactcc attaaagtta gtagtaattg acataaatcc
      301 tgcaagtgaa agtgtggcac gtataccgaa agatacattg tatatccctc caactgcaag
      361 atttatagta ctacttgttg gaaaagttat attagttcca tttataaatg atgaattaaa
      421 tgtcactaat gtattattca ctaaacttga agaggacact gtaaattgtg cattgtttgc
      481 tgctaacact cctgttgctc cggtcgctcc ggttggacct gttgctccat ttgctcctgt
      541 tgctccggtc gcccctgttg ctcctgtcgc tccatttgct ccagttgggc ctgttggtcc
      601 tatcgctcct gctactccat ttgctcccgt tgctcctact gctcc
//
LOCUS       DAYAOO010000221          577 bp    DNA     linear   BCT 12-OCT-2024
DEFINITION  TPA_asm: Clostridioides difficile isolate ST8-SSI-h139-18
            SAMN40601845-rid21577343.denovo.226, whole genome shotgun sequence.
ACCESSION   DAYAOO010000221 DAYAOO010000000
VERSION     DAYAOO010000221.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN40601845
            Sequence Read Archive: SRR28438827
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 577)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 577)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-MAY-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-MAY-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002157583.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002157583.1
            Genome Coverage       :: 163x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/11/2024 16:19:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 4,038
            CDSs (total)                      :: 3,963
            Genes (coding)                    :: 3,930
            CDSs (with protein)               :: 3,930
            Genes (RNA)                       :: 75
            rRNAs                             :: 6, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 60
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 33
            CDSs (without protein)            :: 33
            Pseudo Genes (ambiguous residues) :: 0 of 33
            Pseudo Genes (frameshifted)       :: 7 of 33
            Pseudo Genes (incomplete)         :: 25 of 33
            Pseudo Genes (internal stop)      :: 11 of 33
            Pseudo Genes (multiple problems)  :: 8 of 33
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..577
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN40601845-rid21577343.denovo.226"
                     /isolate="ST8-SSI-h139-18"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Denmark"
                     /collection_date="2018"
                     /collected_by="Statens Serum Institute"
     gene            <1..>577
                     /locus_tag="ACGI5H_003977"
     rRNA            <1..>577
                     /locus_tag="ACGI5H_003977"
                     /product="16S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00177"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00177"
BASE COUNT          154 a          121 c          190 g          112 t
ORIGIN      
        1 caggatggac ccgcgtctga ttagctagtt ggtaaggtaa cggcttacca aggcgacgat
       61 cagtagccga cctgagaggg tgatcggcca cattggaact gagacacggt ccaaactcct
      121 acgggaggca gcagtgggga atattgcaca atgggcgaaa gcctgatgca gcaacgccgc
      181 gtgagtgatg aaggccttcg ggtcgtaaaa ctctgtcctc aaggaagata atgacggtac
      241 ttgaggagga agccccggct aactacgtgc cagcagccgc ggtaatacgt agggggctag
      301 cgttatccgg atttactggg cgtaaagggt gcgtaggcgg tctttcaagt caggagtgaa
      361 aggctacggc tcaaccgtag taagctcttg aaactgggag acttgagtgc aggagaggag
      421 agtggaattc ctagtgtagc ggtgaaatgc gtagatatta ggaggaacac cagttgcgaa
      481 ggcggctctc tggactgtaa ctgacgctga ggcacgaaag cgtggggagc aaacaggatt
      541 agataccctg gtagtccacg ctgtaaacga tgagtac
//
LOCUS       DAYAOO010000222          568 bp    DNA     linear   BCT 12-OCT-2024
DEFINITION  TPA_asm: Clostridioides difficile isolate ST8-SSI-h139-18
            SAMN40601845-rid21577343.denovo.227, whole genome shotgun sequence.
ACCESSION   DAYAOO010000222 DAYAOO010000000
VERSION     DAYAOO010000222.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN40601845
            Sequence Read Archive: SRR28438827
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 568)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 568)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-MAY-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-MAY-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002157583.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002157583.1
            Genome Coverage       :: 163x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/11/2024 16:19:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 4,038
            CDSs (total)                      :: 3,963
            Genes (coding)                    :: 3,930
            CDSs (with protein)               :: 3,930
            Genes (RNA)                       :: 75
            rRNAs                             :: 6, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 60
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 33
            CDSs (without protein)            :: 33
            Pseudo Genes (ambiguous residues) :: 0 of 33
            Pseudo Genes (frameshifted)       :: 7 of 33
            Pseudo Genes (incomplete)         :: 25 of 33
            Pseudo Genes (internal stop)      :: 11 of 33
            Pseudo Genes (multiple problems)  :: 8 of 33
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..568
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN40601845-rid21577343.denovo.227"
                     /isolate="ST8-SSI-h139-18"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Denmark"
                     /collection_date="2018"
                     /collected_by="Statens Serum Institute"
     gene            <1..>568
                     /locus_tag="ACGI5H_003978"
     CDS             <1..>568
                     /locus_tag="ACGI5H_003978"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898421.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9699616.1"
                     /translation="SNSSSYLVMNGAIKYIEKYSGDLKALEYEEPFFYVIKGTHLIKI
                     NAIDESVTFDITLSNDNFSCICITQDYLFISDNTKLYKINKTTGIEVQSIEGSYYKLC
                     TYGEFIYGIYGDETSSILHKIRISDMYKMLTKDMSINSIYDFERGKFVCNKNAIYATT
                     EHANSSGYTDCYLTKINFDFTIAKDFRIG"
BASE COUNT          216 a           55 c           86 g          211 t
ORIGIN      
        1 tttcaaatag ttcatcatat ttagttatga atggtgctat aaaatatatt gaaaaatata
       61 gtggagattt aaaagcatta gaatatgaag aacctttctt ttatgtaatt aaaggtacac
      121 atttaattaa aattaatgca attgatgaat ctgtaacttt tgatattact ttgtctaatg
      181 ataatttctc atgtatttgc attactcaag attatttgtt tatatctgat aatactaaat
      241 tatataaaat aaataagaca acaggaattg aagtgcagtc aatagaaggt tcttattata
      301 agctatgtac ttatggggaa tttatttatg gaatatatgg agatgagact tcttcaatac
      361 ttcacaaaat aagaatatcg gatatgtata aaatgttaac taaagatatg tcaatcaata
      421 gtatttacga ttttgaaaga ggtaagtttg tttgcaataa gaatgctatt tatgctacaa
      481 cagaacacgc taattcaagt ggttatacag attgttacct aactaaaata aattttgatt
      541 ttactattgc taaggatttt agaattgg
//
LOCUS       DAYAOO010000223          496 bp    DNA     linear   BCT 12-OCT-2024
DEFINITION  TPA_asm: Clostridioides difficile isolate ST8-SSI-h139-18
            SAMN40601845-rid21577343.denovo.228, whole genome shotgun sequence.
ACCESSION   DAYAOO010000223 DAYAOO010000000
VERSION     DAYAOO010000223.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN40601845
            Sequence Read Archive: SRR28438827
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 496)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 496)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-MAY-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-MAY-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002157583.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002157583.1
            Genome Coverage       :: 163x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/11/2024 16:19:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 4,038
            CDSs (total)                      :: 3,963
            Genes (coding)                    :: 3,930
            CDSs (with protein)               :: 3,930
            Genes (RNA)                       :: 75
            rRNAs                             :: 6, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 60
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 33
            CDSs (without protein)            :: 33
            Pseudo Genes (ambiguous residues) :: 0 of 33
            Pseudo Genes (frameshifted)       :: 7 of 33
            Pseudo Genes (incomplete)         :: 25 of 33
            Pseudo Genes (internal stop)      :: 11 of 33
            Pseudo Genes (multiple problems)  :: 8 of 33
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..496
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN40601845-rid21577343.denovo.228"
                     /isolate="ST8-SSI-h139-18"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Denmark"
                     /collection_date="2018"
                     /collected_by="Statens Serum Institute"
     gene            <1..>496
                     /locus_tag="ACGI5H_003979"
     CDS             <1..>496
                     /locus_tag="ACGI5H_003979"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009887863.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005525 - GTP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="EF-Tu/IF-2/RF-3 family GTPase"
                     /protein_id="HFG9699617.1"
                     /translation="GTVATGRVERGVLKVQDEVELVGLTEAPRKVVVTGVEMFRKLLD
                     QAQAGDNIGALLRGVQRNEIERGQVLAKTGSVKAHTKFTAEVYVLKKEEGGRHTPFFD
                     GYRPQFYFRTTDVTGACKLPEGIEMVMPGDNVTMEVDLINSIVVEEGLRFSIREGGRT
                     VASGV"
BASE COUNT          213 a           61 c          125 g           97 t
ORIGIN      
        1 ggaacagttg caacaggaag agtggaaaga ggagtactaa aagtacaaga cgaagtagaa
       61 ttagtaggat taacagaagc accaagaaaa gtagtagtaa caggagtaga gatgttcaga
      121 aaattattag accaagcaca agcaggggat aatataggag cattattaag aggagtacaa
      181 agaaacgaga tagaaagagg acaagtacta gcaaagactg gatcagtaaa ggcacacaca
      241 aagtttacag cagaagtata tgtacttaaa aaagaagaag gtggaagaca tacaccattc
      301 tttgatggat atagaccaca attctatttc agaacaacag acgtaacagg agcttgtaag
      361 ttaccagaag gaatagagat ggtaatgcct ggagataacg taacaatgga agtagactta
      421 ataaactcaa tagttgtaga agagggatta agattctcaa taagagaagg tggaagaaca
      481 gtagcttcag gagttg
//
LOCUS       DAYAOO010000224          493 bp    DNA     linear   BCT 12-OCT-2024
DEFINITION  TPA_asm: Clostridioides difficile isolate ST8-SSI-h139-18
            SAMN40601845-rid21577343.denovo.229, whole genome shotgun sequence.
ACCESSION   DAYAOO010000224 DAYAOO010000000
VERSION     DAYAOO010000224.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN40601845
            Sequence Read Archive: SRR28438827
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 493)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 493)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-MAY-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-MAY-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002157583.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002157583.1
            Genome Coverage       :: 163x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/11/2024 16:19:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 4,038
            CDSs (total)                      :: 3,963
            Genes (coding)                    :: 3,930
            CDSs (with protein)               :: 3,930
            Genes (RNA)                       :: 75
            rRNAs                             :: 6, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 60
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 33
            CDSs (without protein)            :: 33
            Pseudo Genes (ambiguous residues) :: 0 of 33
            Pseudo Genes (frameshifted)       :: 7 of 33
            Pseudo Genes (incomplete)         :: 25 of 33
            Pseudo Genes (internal stop)      :: 11 of 33
            Pseudo Genes (multiple problems)  :: 8 of 33
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..493
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN40601845-rid21577343.denovo.229"
                     /isolate="ST8-SSI-h139-18"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Denmark"
                     /collection_date="2018"
                     /collected_by="Statens Serum Institute"
     gene            188..304
                     /gene="rrf"
                     /locus_tag="ACGI5H_003980"
     rRNA            188..304
                     /gene="rrf"
                     /locus_tag="ACGI5H_003980"
                     /product="5S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00001"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00001"
     gene            310..398
                     /locus_tag="ACGI5H_003981"
     tRNA            310..398
                     /locus_tag="ACGI5H_003981"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:344..346,aa:Leu,seq:taa)
     gene            410..486
                     /locus_tag="ACGI5H_003982"
     tRNA            410..486
                     /locus_tag="ACGI5H_003982"
                     /product="tRNA-Ile"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:444..446,aa:Ile,seq:cat)
BASE COUNT          156 a           91 c          109 g          137 t
ORIGIN      
        1 attcattaag atatatgtgc agtttttaga gtgctaactc tatattttta aacttgtcaa
       61 aacttatgaa tttttaatag ttttataagg caaaaaatcg aataaaaaaa gtattgacac
      121 aataagacaa agatgttatt ataatacttg tcttagaaaa aaagttaaat gaaaatttag
      181 acaataatct ggttataata gcagagagga tacacctgtt cccattccga acacagaagt
      241 taagctctct agcgctgatg gtacttggtg ggaaactgcc tgggagagta ggacatagcc
      301 aggtgatgtg ccgaagtggc ggaactggca gacgcacagg acttaaaatc ctgcgggact
      361 tacctctcgt accggttcga ttccggtctt cggcaccaca aattattgtg ggccattagc
      421 tcagttggtt agagcgcccg gctcataacc ggtaggtctg gggttcgagt ccctgatggc
      481 ccaccacaat aat
//
LOCUS       DAYAOO010000225          402 bp    DNA     linear   BCT 12-OCT-2024
DEFINITION  TPA_asm: Clostridioides difficile isolate ST8-SSI-h139-18
            SAMN40601845-rid21577343.denovo.230, whole genome shotgun sequence.
ACCESSION   DAYAOO010000225 DAYAOO010000000
VERSION     DAYAOO010000225.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN40601845
            Sequence Read Archive: SRR28438827
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 402)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 402)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-MAY-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-MAY-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002157583.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002157583.1
            Genome Coverage       :: 163x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/11/2024 16:19:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 4,038
            CDSs (total)                      :: 3,963
            Genes (coding)                    :: 3,930
            CDSs (with protein)               :: 3,930
            Genes (RNA)                       :: 75
            rRNAs                             :: 6, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 60
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 33
            CDSs (without protein)            :: 33
            Pseudo Genes (ambiguous residues) :: 0 of 33
            Pseudo Genes (frameshifted)       :: 7 of 33
            Pseudo Genes (incomplete)         :: 25 of 33
            Pseudo Genes (internal stop)      :: 11 of 33
            Pseudo Genes (multiple problems)  :: 8 of 33
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..402
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN40601845-rid21577343.denovo.230"
                     /isolate="ST8-SSI-h139-18"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Denmark"
                     /collection_date="2018"
                     /collected_by="Statens Serum Institute"
     gene            170..>402
                     /gene="tcdR"
                     /locus_tag="ACGI5H_003983"
     CDS             170..>402
                     /gene="tcdR"
                     /locus_tag="ACGI5H_003983"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434528.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosylating toxin sigma factor TcdR"
                     /protein_id="HFG9699618.1"
                     /translation="MQKSFYELIVLARNNSVDDLQEILFMFKPLVKKLSRVLHYEEGE
                     TDLIIFFIELIKNIKLSSFSEKSDAIIVKYIHKS"
BASE COUNT          169 a           30 c           47 g          156 t
ORIGIN      
        1 ttagaaaaag attactaatt aattattaaa attaatgtat tcataatgta tattttcata
       61 taaaatttaa tttatttgcc gattatataa ttataatgac tgatttaatt ccaatgttgt
      121 caaaattttc aaataaatca tcattataaa tataagagag gatgatttta tgcaaaagtc
      181 tttttatgaa ttaattgttt tagcaagaaa taactcagta gatgatttgc aagaaatttt
      241 atttatgttt aagccattag taaaaaaact tagtagagtt ttacattatg aagagggaga
      301 aacagattta ataatatttt ttattgaatt aataaaaaat attaaattaa gtagcttttc
      361 agaaaaaagc gatgctatta tagtcaaata tattcataaa tc
//
LOCUS       DAYAOO010000226          364 bp    DNA     linear   BCT 12-OCT-2024
DEFINITION  TPA_asm: Clostridioides difficile isolate ST8-SSI-h139-18
            SAMN40601845-rid21577343.denovo.231, whole genome shotgun sequence.
ACCESSION   DAYAOO010000226 DAYAOO010000000
VERSION     DAYAOO010000226.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN40601845
            Sequence Read Archive: SRR28438827
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 364)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 364)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-MAY-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-MAY-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002157583.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002157583.1
            Genome Coverage       :: 163x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/11/2024 16:19:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 4,038
            CDSs (total)                      :: 3,963
            Genes (coding)                    :: 3,930
            CDSs (with protein)               :: 3,930
            Genes (RNA)                       :: 75
            rRNAs                             :: 6, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 60
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 33
            CDSs (without protein)            :: 33
            Pseudo Genes (ambiguous residues) :: 0 of 33
            Pseudo Genes (frameshifted)       :: 7 of 33
            Pseudo Genes (incomplete)         :: 25 of 33
            Pseudo Genes (internal stop)      :: 11 of 33
            Pseudo Genes (multiple problems)  :: 8 of 33
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..364
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN40601845-rid21577343.denovo.231"
                     /isolate="ST8-SSI-h139-18"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Denmark"
                     /collection_date="2018"
                     /collected_by="Statens Serum Institute"
     gene            168..284
                     /gene="rrf"
                     /locus_tag="ACGI5H_003984"
     rRNA            168..284
                     /gene="rrf"
                     /locus_tag="ACGI5H_003984"
                     /product="5S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00001"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00001"
     gene            291..362
                     /locus_tag="ACGI5H_003985"
     tRNA            291..362
                     /locus_tag="ACGI5H_003985"
                     /product="tRNA-Asn"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:323..325,aa:Asn,seq:gtt)
BASE COUNT          117 a           61 c           78 g          108 t
ORIGIN      
        1 attcattaag atatatgtgc agtttttaga gtgttaactc tatgtaaagt actaacttca
       61 attgatgaag tatatatcgt aaaaacaatt actatttagt acttcaaaac tattgacatt
      121 taaaaataaa gatgttaata taatacttgt cttataaata ggcaatatgt ggttataata
      181 gcaaagagga tacacctgtt cccattccga acacagaagt taagctcttt agcgctgatg
      241 gtacttggtg ggaaactgcc tgggagagta ggacgtagcc acgtgaatat tccaaggtag
      301 ctcaatggtg gagcaaccgg ctgttaaccg gtaggctgtg ggttcgagcc ccacccttgg
      361 agcc
//
LOCUS       DAYAOO010000227          331 bp    DNA     linear   BCT 12-OCT-2024
DEFINITION  TPA_asm: Clostridioides difficile isolate ST8-SSI-h139-18
            SAMN40601845-rid21577343.denovo.233, whole genome shotgun sequence.
ACCESSION   DAYAOO010000227 DAYAOO010000000
VERSION     DAYAOO010000227.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN40601845
            Sequence Read Archive: SRR28438827
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 331)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 331)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-MAY-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-MAY-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002157583.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002157583.1
            Genome Coverage       :: 163x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/11/2024 16:19:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 4,038
            CDSs (total)                      :: 3,963
            Genes (coding)                    :: 3,930
            CDSs (with protein)               :: 3,930
            Genes (RNA)                       :: 75
            rRNAs                             :: 6, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 60
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 33
            CDSs (without protein)            :: 33
            Pseudo Genes (ambiguous residues) :: 0 of 33
            Pseudo Genes (frameshifted)       :: 7 of 33
            Pseudo Genes (incomplete)         :: 25 of 33
            Pseudo Genes (internal stop)      :: 11 of 33
            Pseudo Genes (multiple problems)  :: 8 of 33
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..331
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN40601845-rid21577343.denovo.233"
                     /isolate="ST8-SSI-h139-18"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Denmark"
                     /collection_date="2018"
                     /collected_by="Statens Serum Institute"
     gene            complement(<1..>331)
                     /locus_tag="ACGI5H_003986"
     rRNA            complement(<1..>331)
                     /locus_tag="ACGI5H_003986"
                     /product="23S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF02541"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF02541"
BASE COUNT           76 a           87 c           55 g          113 t
ORIGIN      
        1 aggactatta ccttctgtgg tgggtctttc caaacctctt caattacgat acctcttcgt
       61 tatgatatgt ccgcaacccc aataaagaaa actttattgg tttgggctaa tccgcgttcg
      121 ctcgccgcta cttacggaat cgaatttctt tctcttcctt caggtactta gatgtttcag
      181 ttccctgagt tcccctcatt aagctatgta ttcacttaat gatacttaga cattactcta
      241 agtgagtttc ctcattcgga aatcttcgga tcaaagttta cgtgcaactc cccgaagctt
      301 atcgcagctt atcacgtcct tcatcggctc c
//
LOCUS       DAYAOO010000228          322 bp    DNA     linear   BCT 12-OCT-2024
DEFINITION  TPA_asm: Clostridioides difficile isolate ST8-SSI-h139-18
            SAMN40601845-rid21577343.denovo.234, whole genome shotgun sequence.
ACCESSION   DAYAOO010000228 DAYAOO010000000
VERSION     DAYAOO010000228.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN40601845
            Sequence Read Archive: SRR28438827
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 322)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 322)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-MAY-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-MAY-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002157583.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002157583.1
            Genome Coverage       :: 163x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/11/2024 16:19:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 4,038
            CDSs (total)                      :: 3,963
            Genes (coding)                    :: 3,930
            CDSs (with protein)               :: 3,930
            Genes (RNA)                       :: 75
            rRNAs                             :: 6, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 60
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 33
            CDSs (without protein)            :: 33
            Pseudo Genes (ambiguous residues) :: 0 of 33
            Pseudo Genes (frameshifted)       :: 7 of 33
            Pseudo Genes (incomplete)         :: 25 of 33
            Pseudo Genes (internal stop)      :: 11 of 33
            Pseudo Genes (multiple problems)  :: 8 of 33
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..322
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN40601845-rid21577343.denovo.234"
                     /isolate="ST8-SSI-h139-18"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Denmark"
                     /collection_date="2018"
                     /collected_by="Statens Serum Institute"
BASE COUNT          132 a           36 c           40 g          114 t
ORIGIN      
        1 tatcaagcga tagcgaattt acagaaggaa tattacaaag tgatgaagca gaaatgacga
       61 cgaatgtagg atttataatc gaaggattaa gttatcataa tgactaaatc tttagcatta
      121 aaaaagcagt gtatttatta aatacactgc ttttatttcc gcatagttaa tataaaataa
      181 tgtgatatta tatcatgtga atatagatta aattgatatt taaatccctt atagttaatc
      241 taaaaaatac cattatatca tttctctata aattaaattg acatttaaat cccttgtagt
      301 taatataaaa attcttatta ca
//
LOCUS       DAYAOO010000229          308 bp    DNA     linear   BCT 12-OCT-2024
DEFINITION  TPA_asm: Clostridioides difficile isolate ST8-SSI-h139-18
            SAMN40601845-rid21577343.denovo.235, whole genome shotgun sequence.
ACCESSION   DAYAOO010000229 DAYAOO010000000
VERSION     DAYAOO010000229.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN40601845
            Sequence Read Archive: SRR28438827
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 308)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 308)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-MAY-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-MAY-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002157583.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002157583.1
            Genome Coverage       :: 163x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/11/2024 16:19:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 4,038
            CDSs (total)                      :: 3,963
            Genes (coding)                    :: 3,930
            CDSs (with protein)               :: 3,930
            Genes (RNA)                       :: 75
            rRNAs                             :: 6, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 60
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 33
            CDSs (without protein)            :: 33
            Pseudo Genes (ambiguous residues) :: 0 of 33
            Pseudo Genes (frameshifted)       :: 7 of 33
            Pseudo Genes (incomplete)         :: 25 of 33
            Pseudo Genes (internal stop)      :: 11 of 33
            Pseudo Genes (multiple problems)  :: 8 of 33
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..308
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN40601845-rid21577343.denovo.235"
                     /isolate="ST8-SSI-h139-18"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Denmark"
                     /collection_date="2018"
                     /collected_by="Statens Serum Institute"
BASE COUNT          125 a           30 c           61 g           92 t
ORIGIN      
        1 aacagtatat tcattgacaa atataagttt taagtatata ttaaaaatta ttagagtgtg
       61 cattagaatg tatacagcgt atattaagaa ttattagagt gtatataagg atgtatacag
      121 tgtatattaa aaattattaa ggggaggggg agtttatgca acaaaaatgt aaaaagaaag
      181 cactatcaat gattttaagt atctcaatgg gacttggacc agtagcatca tttaatgcgt
      241 caaatacttt cgcagatact atagaagaaa gtactaatgc aggaaatgca gaaggaggta
      301 ctaatgca
//
LOCUS       DAYAOO010000230          301 bp    DNA     linear   BCT 12-OCT-2024
DEFINITION  TPA_asm: Clostridioides difficile isolate ST8-SSI-h139-18
            SAMN40601845-rid21577343.denovo.236, whole genome shotgun sequence.
ACCESSION   DAYAOO010000230 DAYAOO010000000
VERSION     DAYAOO010000230.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN40601845
            Sequence Read Archive: SRR28438827
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 301)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 301)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-MAY-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-MAY-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002157583.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002157583.1
            Genome Coverage       :: 163x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/11/2024 16:19:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 4,038
            CDSs (total)                      :: 3,963
            Genes (coding)                    :: 3,930
            CDSs (with protein)               :: 3,930
            Genes (RNA)                       :: 75
            rRNAs                             :: 6, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 60
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 33
            CDSs (without protein)            :: 33
            Pseudo Genes (ambiguous residues) :: 0 of 33
            Pseudo Genes (frameshifted)       :: 7 of 33
            Pseudo Genes (incomplete)         :: 25 of 33
            Pseudo Genes (internal stop)      :: 11 of 33
            Pseudo Genes (multiple problems)  :: 8 of 33
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..301
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN40601845-rid21577343.denovo.236"
                     /isolate="ST8-SSI-h139-18"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Denmark"
                     /collection_date="2018"
                     /collected_by="Statens Serum Institute"
     gene            complement(<1..>301)
                     /locus_tag="ACGI5H_003987"
     CDS             complement(<1..>301)
                     /locus_tag="ACGI5H_003987"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018112542.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine-rich protein"
                     /protein_id="HFG9699619.1"
                     /translation="GSYSPYTGGAGGGLAGGTGYSANDRHRPGGTQYQGGIGRVSTEN
                     GSFGKGCSAKDSTGEGGGGGWFGGAGMNGAGAGGGGSGYVLTKDSYKPTGYTPTSE"
BASE COUNT           74 a           99 c           47 g           81 t
ORIGIN      
        1 attcagatgt tggtgtgtag ccagtaggct tataactatc tttagttaat acgtagccac
       61 ttccacctcc acctgctccc gcaccattca ttcctgcacc accaaaccag ccacctccac
      121 cgccttcgcc agttgaatct ttagcagaac acccttttcc aaaacttccg ttttctgtgc
      181 ttacacgacc aataccacct tgatattgag taccgccggg acgatgtctg tcgttagcac
      241 tatacccagt acctcctgct aatcctcctc ctgcaccacc agtataagga gaatatgaac
      301 c
//
LOCUS       DAYAOO010000231          268 bp    DNA     linear   BCT 12-OCT-2024
DEFINITION  TPA_asm: Clostridioides difficile isolate ST8-SSI-h139-18
            SAMN40601845-rid21577343.denovo.237, whole genome shotgun sequence.
ACCESSION   DAYAOO010000231 DAYAOO010000000
VERSION     DAYAOO010000231.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN40601845
            Sequence Read Archive: SRR28438827
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 268)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 268)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-MAY-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-MAY-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002157583.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002157583.1
            Genome Coverage       :: 163x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/11/2024 16:19:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 4,038
            CDSs (total)                      :: 3,963
            Genes (coding)                    :: 3,930
            CDSs (with protein)               :: 3,930
            Genes (RNA)                       :: 75
            rRNAs                             :: 6, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 60
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 33
            CDSs (without protein)            :: 33
            Pseudo Genes (ambiguous residues) :: 0 of 33
            Pseudo Genes (frameshifted)       :: 7 of 33
            Pseudo Genes (incomplete)         :: 25 of 33
            Pseudo Genes (internal stop)      :: 11 of 33
            Pseudo Genes (multiple problems)  :: 8 of 33
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..268
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN40601845-rid21577343.denovo.237"
                     /isolate="ST8-SSI-h139-18"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Denmark"
                     /collection_date="2018"
                     /collected_by="Statens Serum Institute"
BASE COUNT          129 a           20 c           25 g           94 t
ORIGIN      
        1 ttttaaataa aaaaataaaa tattagtttt gatttctggt ttaaattggg ttataataaa
       61 ttgtcaaatt atttattaat ataaaataga ctataaaaca agcaaaaatc atactattat
      121 ataaaagacc ttaaagatag aaaactacag aaagaagcca aaatgttttt gaaaaaaatg
      181 aaattttatt gcaaaaaaat caaaatgaat ttaacttaat agttataatc tatttttagt
      241 gttacaaata tacaatgtat attataca
//
LOCUS       DAYAOO010000232        17089 bp    DNA     linear   BCT 12-OCT-2024
DEFINITION  TPA_asm: Clostridioides difficile isolate ST8-SSI-h139-18
            SAMN40601845-rid21577343.guided.088, whole genome shotgun sequence.
ACCESSION   DAYAOO010000232 DAYAOO010000000
VERSION     DAYAOO010000232.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN40601845
            Sequence Read Archive: SRR28438827
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 17089)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 17089)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-MAY-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-MAY-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002157583.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002157583.1
            Genome Coverage       :: 163x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/11/2024 16:19:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 4,038
            CDSs (total)                      :: 3,963
            Genes (coding)                    :: 3,930
            CDSs (with protein)               :: 3,930
            Genes (RNA)                       :: 75
            rRNAs                             :: 6, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 60
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 33
            CDSs (without protein)            :: 33
            Pseudo Genes (ambiguous residues) :: 0 of 33
            Pseudo Genes (frameshifted)       :: 7 of 33
            Pseudo Genes (incomplete)         :: 25 of 33
            Pseudo Genes (internal stop)      :: 11 of 33
            Pseudo Genes (multiple problems)  :: 8 of 33
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..17089
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN40601845-rid21577343.guided.088"
                     /isolate="ST8-SSI-h139-18"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Denmark"
                     /collection_date="2018"
                     /collected_by="Statens Serum Institute"
     gene            complement(150..674)
                     /locus_tag="ACGI5H_003988"
     CDS             complement(150..674)
                     /locus_tag="ACGI5H_003988"
                     /EC_number="5.2.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434191.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003755 - peptidyl-prolyl cis-trans
                     isomerase activity [Evidence IEA];
                     GO_process: GO:0000413 - protein peptidyl-prolyl
                     isomerization [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase"
                     /protein_id="HFG9699620.1"
                     /translation="MENKNPIVTIEMENGKEIKIELYPNIAPNTVKNFVSLVNEGYYN
                     GIIFHRVIPGFMIQGGCPNGTGMGGPGHSIKGEFSGNGFTNNLKHERGVISMARTMAP
                     NSAGSQFFIMHKNSPHLDGQYAGFGRVIEGMDTVDEIASVRTDSADKPQTPQVMKSVT
                     VETFGIDYSDVEKN"
     gene            complement(739..1491)
                     /locus_tag="ACGI5H_003989"
     CDS             complement(739..1491)
                     /locus_tag="ACGI5H_003989"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417271.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="patatin-like phospholipase family protein"
                     /protein_id="HFG9699621.1"
                     /translation="MKLGLCLEGGGAKGAYQAGVVKALYDGGINKFYSISGTSIGAIN
                     GYYLYTGNVDNLEKMWTNIKDIQNGNVKIVNNTVDNSPAIDNLRELDDSNIEEMNFYV
                     NYVEVDNKVVSEKIVDVSKMPRNEAIISISYSGLLPSNPNATLGFKEQFVKDVQEGIY
                     DGFKLDGGLIRSALIEPLIGDNVDKIILISTKYNYELPEDIKKVYDEDKIIVVRPNTQ
                     FAPKDTLNFDDEFCKTIYQEGYEIGKNILDRL"
     gene            complement(1522..2820)
                     /locus_tag="ACGI5H_003990"
     CDS             complement(1522..2820)
                     /locus_tag="ACGI5H_003990"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888187.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004177 - aminopeptidase activity
                     [Evidence IEA];
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="M18 family aminopeptidase"
                     /protein_id="HFG9699622.1"
                     /translation="MDSINFAKNLIDFIYDSPSSFHAVESTKEILDKNGFEELVLNQR
                     WNLRVGGKYYVTKNLSAIVAFVVNSEGIERDGFRIIGSHSDSPTFSIKPNAEIEAEKS
                     YLKLNTECYGGAILSTWLDRPLGIAGRVVLKGDSILKPNERLIDFKKPICIIPNLAIH
                     LNRSINDGHSYNKQKDMLPLVGMLNDTLEKDNFLIKQIASNLDVNMDDIIDFDLFLYE
                     FEKGSLIGANDEFISIGRQDNLAMVHASLNALVNTKGQHGVNVMAVFDNEEVGSSTKQ
                     GADSNMLLNILERICISMGKDREGFFESIYSSFMISSDLAHAIHPNIPEKHDPTNKPI
                     MGKGPVIKINASQAYTSDGYSIAIYKNICREANVEYQEFVNRSDERGGSTIGPISSTH
                     IDIPSVDVGSPILAMHSIRELGNVEDHYSIYKTFSKFFEI"
     gene            complement(2837..5101)
                     /locus_tag="ACGI5H_003991"
     CDS             complement(2837..5101)
                     /locus_tag="ACGI5H_003991"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3553 domain-containing protein"
                     /protein_id="HFG9699623.1"
                     /translation="MNLDTLNPAQREAVEKTEGPVLILAGAGSGKTKVLTTRIAYLIE
                     DKGVQAPNILAITFTNKAANEMRERVEQNIGPETKDMWISTFHSCCVRILRKDINKIG
                     YNRSFVIYDSADQVTLVKDCLKELNLSDKVFEPKAVISAISGAKDKLYTPKQFKDINM
                     ADNRMVKIADIYALYQDRLKRNSALDFDDLILKTVELFKANDEVLAYYRSRFRYIMVD
                     EYQDTSKAQYELIKLLAREHQNICVVGDDDQSIYGWRGADIRNILEFEKDYDNVHVVK
                     LEQNYRSTQVILDAANKVISNNIERKRKKLWSEKKEGELIKIQLTGSEIEEADFIADS
                     IAQIARKENRPYKDFAVLYRANAQARPVEDALNRSQIPYNIYGGTKFYERKEIKDLLA
                     YLRVIQNPQDDISIKRIINVPRRGIGLRTIEKIEDRANLKQESIYSVLIDIETNSDIS
                     TKARASISGFVDIIGTLRTIKEVYPVSKLIEKVLDTTGYMDELVEIRNKNEKDLTGKG
                     EEAQDRIDNLREFISIALEFESSNDDTYENKDLETFLTSIALTSESNDEEDNDRVSLM
                     TIHTSKGLEFPVVFLTGMEEGLFPISRAIKSMSDSQIEEERRLCYVGITRAKEELYMS
                     LTEKRTLYGKTNVAIASRFMEELPEECIERLYKVKKELSYSKASYNMLDKYTKKYMST
                     ISKSKVADKVNATIKDSNKETNPDDIKLGSKVHHPKFGVGTVVSIIGTDVTIAFDQQG
                     IKKINKEYTTLNIL"
     gene            complement(5356..6174)
                     /locus_tag="ACGI5H_003992"
     CDS             complement(5356..6174)
                     /locus_tag="ACGI5H_003992"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009904855.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor ABC transporter
                     ATP-binding protein"
                     /protein_id="HFG9699624.1"
                     /translation="MFKINNLTYQYEKNTNALLNINMDFSKGNVIGIIGSNGSGKSTL
                     FMNLMGILKPTSGEILFKEEKLKYDKRSLYNLRKNVGIVFQDPEKQIFYSKVYDDIAF
                     AMRNIGMDEKTIKERINKALVAVNGIDFIDRPVHFLSYGQKKRVAIASVIAMENEIVL
                     LDEPTAGLDPVSTRSIVDIIKGLNKNNIKIVISSHDMNLMYEICDYIYVLDKGILIDE
                     GKAENVFINENNIIQAGLESPWLVKVHRNMNLPLFKKEEDLYKYWKERELNTNK"
     gene            complement(6167..6865)
                     /gene="cbiQ"
                     /locus_tag="ACGI5H_003993"
     CDS             complement(6167..6865)
                     /gene="cbiQ"
                     /locus_tag="ACGI5H_003993"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417243.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_component: GO:0043190 - ATP-binding cassette (ABC)
                     transporter complex [Evidence IEA];
                     GO_function: GO:0032778 - P-type cobalt transporter
                     activity [Evidence IEA];
                     GO_process: GO:0006824 - cobalt ion transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cobalt ECF transporter T component CbiQ"
                     /protein_id="HFG9699625.1"
                     /translation="MLIIDKYAYTNRLSKVNPNKKVAIGVIFLIASMVIQNIFILSGI
                     MILMSILVVCVAGIDLKNYLKLLRIPMYFLFLSIGITLVNISFNKADLLYSFEFFSFN
                     VGISKASINMSIHVLFRAMSCLTCVYFCILTTPFNQLIFFFKKLHLPDTFVELSMLIY
                     RFIFIFLEEFSEIYKSQELRFGYINLKTSYKSLGILGSMLYKRLMTRYDDMCISLDIK
                     LYDGKFHIVGDNDV"
     gene            complement(6868..7152)
                     /locus_tag="ACGI5H_003994"
     CDS             complement(6868..7152)
                     /locus_tag="ACGI5H_003994"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895390.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0015087 - cobalt ion transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0006824 - cobalt ion transport [Evidence
                     IEA];
                     GO_process: GO:0009236 - cobalamin biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor ABC transporter
                     substrate-binding protein"
                     /protein_id="HFG9699626.1"
                     /translation="MSAKTKTKTNILLLLLVVALIIFPLLVNSGAEYGGADGQAESEI
                     TKINPNYKPWFSSPYEPPSGEIESLLFSAQAALGAGVIGYILGLQKGKRS"
     gene            complement(7142..7894)
                     /locus_tag="ACGI5H_003995"
     CDS             complement(7142..7894)
                     /locus_tag="ACGI5H_003995"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427152.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_component: GO:0043190 - ATP-binding cassette (ABC)
                     transporter complex [Evidence IEA];
                     GO_process: GO:0000041 - transition metal ion transport
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor ABC transporter permease"
                     /protein_id="HFG9699627.1"
                     /translation="MKQNIKLGVIAALMLIILTPVTSNAMHIMEGYLPVKWSIAWGVI
                     FIPFFLFGLKSIGKIVKQDPKKKVLLALCGAFVFVLSALKIPSVTGSCSHPTGVGLGA
                     IMFGPSVMFVLGTIVLIFQALLLAHGGITTLGANAFSMAIIGPIVSFLIFKALKKKDG
                     NNAIPVFLAAAIGDLATYTITSIQLALAFPDPSGGVMASAIKFLGIFFMTQIPIAIAE
                     GILTVIVYNLITENGEKSILENNDKGVKANEC"
     regulatory      complement(8076..8268)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00174"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="cobalamin riboswitch; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="adenosylcobalamin"
                     /db_xref="RFAM:RF00174"
     gene            complement(8400..10172)
                     /locus_tag="ACGI5H_003996"
     CDS             complement(8400..10172)
                     /locus_tag="ACGI5H_003996"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427150.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nitric oxide reductase activation-like protein"
                     /protein_id="HFG9699628.1"
                     /translation="MKWIYDDYEFENRANNLSWTIAGDYNESIDISEKDYSSKEIGLY
                     FAIIAGARRKYVDWDIVKKYLTNRIRKGYNKDVILGLIQVILNTIVEEKVIKDRPGIE
                     DIRRNAYKDIVSRFTKIHNDNIMDKIKYTFVLYSMDKHPALDSMTRRIVNDIRNIDTN
                     QDIMEILKALDVIYLTYFEYILNGEENSLIDENNVESVEVNFDTFADFMYEELYSDEE
                     ENIIESDIDSISSSMLVEGVGDFDDSKCSNSADRVIYVDEDTANKIYSKIEHYYGKTY
                     LSKGEIKKIETQNCRNVHEGCRIHFTDGVLRSECNNVFQLKYVTRQKENNLGKFREHA
                     RMYRQQIKRLKESLSRILIEENAKSRVYSDCGTILANRAWRVGRSNNNKIFYKDIENE
                     KGKYVIDILLDASGSQSRNQGNVAIQAYIIANALTEVGIPNRVMGFSSFLDYTILKRF
                     KDYDDSIKNSENIFEYFCAGNNRDGLAIKSICSGLINRDEENKILIVLSDGRPNDVKI
                     GKSSERTLRGEKAYRGIVGLRDTANEVRKARKQNILVLGVFTGKESELEAERLIYGND
                     FIYSRDITRFSDVVSMYLKKIIRN"
     gene            complement(10186..11115)
                     /locus_tag="ACGI5H_003997"
     CDS             complement(10186..11115)
                     /locus_tag="ACGI5H_003997"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434205.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HFG9699629.1"
                     /translation="MDIIDNLRVQGVDEKLIEDVLYFRNYYGLEKDLEYRVTKSKTYF
                     YGKDILSMCIAAILEEENILLSGPKATGKNLLADNLGEIFNRPQWNTSFHINTDSSTL
                     IGTDTFIDNEVKLRRGSVYECAINGGFGVFDEINMAKNDAIVVVHSALDYRRIIDVPG
                     YERVNLHPATRFIGTMNYEYAGTKELNEALVSRFMVIDIPPIEEDKLMMILKNEFSDA
                     DEEKLIHFAGIFLDLQLKSQNGEISSKAIDLRGLMASLKTIRRGLKPTLAINMGLTGK
                     TFDVYEKEMVGDVIKTRIPNKWESIDVFPISHI"
     gene            11336..11521
                     /locus_tag="ACGI5H_003998"
     CDS             11336..11521
                     /locus_tag="ACGI5H_003998"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888180.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein"
                     /protein_id="HFG9699630.1"
                     /translation="MKYGCPEVAKKWGISERRVQKLCEESRIPGVSKLGYMWLIPKNA
                     EKPVDGRTKRRKEVQYE"
     gene            11514..12215
                     /locus_tag="ACGI5H_003999"
     CDS             11514..12215
                     /locus_tag="ACGI5H_003999"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434208.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000156 - phosphorelay response regulator
                     activity [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HFG9699631.1"
                     /translation="MNSVLIIDDDKELCALMKKCVEQENLSAITAHCGAEGLHLVDKN
                     RHTLSLVILDIMMPDIDGFQVLKKIRETSNIPVIMLTAKNDEDDKVSGLRLGADDYLT
                     KPFSINELMARVNSLIRRYTMLNPAFITDTDCIIINGMIIDKTNRIVSVNNIPVQLTS
                     KEFDLLAFLASNKGRVFTKKQIYTQVWEEEYAFDDSNIMSFISKLRKKIEPDPNHPFY
                     ILTVRGVGYRFNKEA"
     gene            12217..13140
                     /locus_tag="ACGI5H_004000"
     CDS             12217..13140
                     /locus_tag="ACGI5H_004000"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427141.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing sensor histidine kinase"
                     /protein_id="HFG9699632.1"
                     /translation="MNTSVYLLLILVLSLIIIAYLVSVLLRVRIQLTLIKDALEDIKN
                     GNLNRRILTDENDITKQICYDINEIAINSQFQLIQQKQSEQAYKQLMTSLSHDVKTPL
                     ASLVGYLEAVESKIVVGEEKDEYIHVASNKAHYLKNFVENLFEWVKLDSKEQVFHFDI
                     FDLNELSRNIISDWIPVLESSHFEYEFDIPEIEYFLRIDANAYTRIINNLLQNIITHS
                     SGNKMTLRIFENKEQAQIIITDNGKGISSDNLPHIFERLYQCDHSRASKGNGLGLAIA
                     KELINAHKGNITANSTPGMGTEFTILLPKAL"
     gene            13297..14220
                     /locus_tag="ACGI5H_004001"
     CDS             13297..14220
                     /locus_tag="ACGI5H_004001"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019639192.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HFG9699633.1"
                     /translation="MNDFVIETKQLTKIYGNQTVVDKVNLHAKKGRIYGLLGRNGAGK
                     TTIMKMILGLTSITYGEVDVFGENIKGREKQVYPRIGAIIETPGFYPNLTGTENLEIF
                     AKLRGTAAPNSVKRALEIVGLPYKNKKLFSEYSLGMKQRLGIANAILHDPELLVLDEP
                     TNGLDPIGIAEMRKFIRDLSVEHGKTILISSHILSEISLLADDIGIIDHGVLLEESSM
                     SELEKKNSKYILLQVSDIPKTSLILERQFNTKDYSVQDDYTLHLYNTNLDMGEINKAL
                     VMQNVTVISSQLCNDTLEDYFKKITGGEGIA"
     gene            14213..14950
                     /locus_tag="ACGI5H_004002"
     CDS             14213..14950
                     /locus_tag="ACGI5H_004002"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434216.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HFG9699634.1"
                     /translation="MLKLIQTEFLKLRRRKLIWLMLLSALIMPFFALLYFNYFGKTGV
                     EPIKFYKWSAFGYTLWIILPVVLGIFCTMLIHEENQYDMLKQLWIVPISKMGYFFSKF
                     FVVLIYSICFMLITAVASVLFSVLSGYVVFSWASILYLLKKCLEIGVITAFVMLPILA
                     IATSQKGYILPICITLVYAFSGFVIMTINMYLHPLSSMGVIIMRNKDIPGLIFSQEIN
                     VPLAFLCICIWSIVSVLFANTALGRRK"
     gene            14961..15734
                     /locus_tag="ACGI5H_004003"
     CDS             14961..15734
                     /locus_tag="ACGI5H_004003"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434217.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HFG9699635.1"
                     /translation="MWKLLWAECQKIRRSKIVWITVFASIMIAVIVFAGGQDVYNDPD
                     LHYGLKSVYDGSRYIDNAGWYMDAVQPWSTFFVLPAVIALLGSYIICREEEEDTIKSL
                     RLIPINETKLTIAKMIITFIFSILLYLLLFTITFLTESVLHFSDLSTKLVLSCMKEYF
                     LDGIGVFFAISPIIALVSRMKKGYWLALVFTEVYSIAGLFAGMSNVLQTFFPIAAIFN
                     ISGYYITTGEKIMGSIISLLLCACLSAFILKGLKHNEKN"
     gene            complement(16275..16883)
                     /locus_tag="ACGI5H_004004"
     CDS             complement(16275..16883)
                     /locus_tag="ACGI5H_004004"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895382.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DedA family protein"
                     /protein_id="HFG9699636.1"
                     /translation="MSVINSFILQYGLISVFVLIMIEYACFPLPSEVVLPLCGAIAAR
                     NHFGFLTILILSIIAGILGSIFCYTVGNWGGKSIINKIIEICPKAKKGIFASQDYFNK
                     YSSISVCVCRLIPLCRTYISFIAGIAGQNIITFVISSIVGITIWNTSLISIGYIFSES
                     WVRIMSHYNDYKFLVLIIPISIIFIGFVIKSFIHKKHHKIRL"
BASE COUNT         5506 a         2966 c         2163 g         6454 t
ORIGIN      
        1 atacaatata tagatttcca caatacaaat aaattaaaaa gtgaaatgta tttgtctaaa
       61 aacataataa catttcactt tatcctcatt tttaagtaat atatattttt aatttttatt
      121 tataactaaa tctagttttt atataaattt tagttttttt ctacatctga gtaatctatt
      181 ccaaaagttt ctacagtaac agatttcata acttgtggag tttgtggctt atcagctgaa
      241 tctgttctaa ctgatgctat ttcatcaact gtatccatac cttctatcac tctaccaaaa
      301 cctgcatact gaccatctaa gtgtggtgag tttttatgca ttatgaaaaa ttgagaacca
      361 gctgaattag gtgccatagt tctagccatt gatatgactc ctctttcatg ttttaaattg
      421 ttagtaaatc cattaccact aaattcacct tttattgagt gacctggacc acccattcct
      481 gtaccatttg ggcatcctcc ttgtatcata aatcctggta ttactctatg aaatattatt
      541 ccattgtaat atccttcatt tactaatgat acaaagtttt taactgtatt tggagctata
      601 tttggatata actcaatttt gatttctttt ccattttcca tttctatagt tactatagga
      661 tttttatttt ccataattta ttaccttcct tttcattagt taaattacat aattacattt
      721 attatattat actctaaatt aaagtctatc aagtatattt tttcctattt catatccttc
      781 ttgataaata gttttacaaa actcatcatc aaagttaagc gtgtctttag gagcaaattg
      841 agtattaggt ctaactacta ttattttatc ttcatcatat acttttttaa tatcttctgg
      901 caactcataa ttatattttg tggatattaa aataatttta tccacattat ccccaattaa
      961 tggttcaatt aatgcactcc taattaaacc tccatctaat ttgaaaccat cataaattcc
     1021 ttcttgcaca tctttcacaa attgttcttt aaatccaaga gttgcgtttg gatttgatgg
     1081 taacaaccca ctgtatgaaa tgctgataat ggcttcatta cgaggcattt ttgatacgtc
     1141 aacaatcttt tctgatacta ctttattatc aacttcaaca taattaacat aaaagttcat
     1201 ttcttctata ttactatcat ctagttccct taggttgtct atagcaggag aattatccac
     1261 agtattattt actattttta catttccatt ctggatatct tttatatttg tccacatttt
     1321 ctccaagtta tcaacattcc ctgtgtacaa ataatatcca tttattgctc ctattgatgt
     1381 ccctgaaatc gaataaaatt tatttattcc tccatcatac aaggctttaa ctactcctgc
     1441 ttgataagcc ccttttgctc ctccaccttc taaacataat cctaatttca tagtctcatc
     1501 tccaaattgt ttatcttata tttatatttc aaaaaactta ctaaatgttt tatatatact
     1561 atagtggtcc tcaacatttc ctaattctct tatagaatgc attgctaaaa ttggacttcc
     1621 cacatccaca gatggtatat ctatatgagt agaagatatt ggacctatag tacttcctcc
     1681 tctttcatct gacctattaa caaattcttg atactcaaca ttagcttctc tacatatatt
     1741 tttataaata gctatagaat atccatcact agtatatgcc tgactagcat ttatctttat
     1801 aaccggacct tttcccatta ttggtttatt agttgggtca tgcttttctg gaatgtttgg
     1861 atgaatagca tgagctaaat ctgatgatat cataaaagat gaataaatag actcaaagaa
     1921 tccctctcta tccttaccca ttgatatgca aattctctcc aatatattta acaacatgtt
     1981 tgaatctgca ccttgtttag tagagctacc aacttcttca ttgtcaaata cagccattac
     2041 atttacacca tgttgacctt tagtattaac aagagcattc aaactagcat gtaccattgc
     2101 aagattatct tgtctcccaa tagatataaa ttcatcatta gcccctatta aacttccttt
     2161 ttcaaattca tataaaaata aatcaaaatc tataatatcg tccatattta catctaagtt
     2221 agatgctatt tgctttataa gaaaattatc tttttctaat gtatcattta acatcccaac
     2281 taaaggtaac atatcttttt gcttattata tgagtgacca tcatttatac ttctatttaa
     2341 atgtattgct agatttggta ttatacaaat tggcttttta aagtctataa gcctttcatt
     2401 tggttttaat atactatcac cttttaaaac tactctacca gctatcccaa gaggtctatc
     2461 caaccatgta cttaatattg ctcctccata gcattctgta tttaacttca aataagattt
     2521 ttcagcttct atttctgcat ttggtttaat actaaatgta ggagaatctg aatgagagcc
     2581 tattattcta aatccatctc tttctatacc ttctgaattt actacaaaag ctactatagc
     2641 tgataaattc ttagtaacat aatactttcc accaactctt agattccatc tttgattcaa
     2701 aactaattct tcaaatccat ttttatctaa gatttcctta gtactctcga ctgcatgaaa
     2761 agacgacgga ctatcatata tgaagtctat taagttttta gcaaagttta tactatccat
     2821 tcctcattta cctccattat aaaatattta gtgttgtata ttctttattt atttttttaa
     2881 ttccctgttg gtcaaaagct atagtaacat ctgtaccaat tatagaaacc actgtcccaa
     2941 ccccaaattt aggatgatgt accttagaac caagttttat atcatctgga ttagtttctt
     3001 tattagaatc ttttattgta gcattaactt tatctgcaac tttagatttg cttatagtac
     3061 tcatatactt tttagtatat ttatctaaca tattataact tgctttagaa tagcttagtt
     3121 ctttttttac tttgtacaat ctttctatac attcttctgg cagttcttcc ataaatcttg
     3181 aagctattgc aacatttgtt ttaccatata atgttctctt ctctgtcaat gacatatata
     3241 gctcttcttt agctctagtt ataccaacat aacaaagtct tctctcttct tctatttgtg
     3301 aatcactcat agattttata gctcttgata taggaaataa cccttcttcc atacctgtta
     3361 aaaacacaac agggaactct aaacctttgg atgtatgaat tgtcataagc gaaaccctat
     3421 cattgtcttc ttcatcattt gattcagatg taagtgctat acttgttagg aatgtctcta
     3481 agtctttatt ttcataagta tcatcattac tactttcaaa ctccaaagct atagaaataa
     3541 attctctcaa attatcaatt ctgtcttgag cttcttcacc tttgcctgtt aaatcttttt
     3601 catttttatt tcttatctct acaagctcgt ccatatatcc tgtagtatcc aagacttttt
     3661 ctataagttt gctaacagga taaacttctt ttatagttct aagagtccct ataatatcaa
     3721 caaatccact tatacttgcc cttgccttag tagatatatc tgaatttgtt tctatatcaa
     3781 ttaatactga gtatatactt tcctgtttta agttagctct atcttcaatt ttttctatag
     3841 ttctaagccc tatacctctt ctaggaacat ttataatcct ttttatagat atatcatctt
     3901 gtggattttg aataactctt aaatacgcca acaaatcctt tatttctttt ctctcataga
     3961 attttgtacc accatatata ttgtatggaa tttgacttct atttaaagcg tcctctacag
     4021 gtcttgcctg tgcatttgct ctataaagta ctgcaaaatc cttataaggt ctattttctt
     4081 ttctagctat ttgtgcaatt gaatcagcaa tgaaatcagc ctcttctatt tcactaccag
     4141 ttaattgtat ctttataagt tctccttctt ttttttcact ccaaagcttt tttctttttc
     4201 tttctatatt attagatata actttattag ctgcatctaa tataacttgt gtagacctat
     4261 aattttgttc caactttaca acatgtacat tgtcataatc tttctcaaat tcaagtatgt
     4321 ttcttatatc tgcacctctc catccataaa tactttggtc atcatctcca acaacacaaa
     4381 tattttgatg ttctcttgct aataatttta tcaattcata ttgagcttta cttgtatctt
     4441 ggtactcatc taccattatg tatctaaatc tacttctgta atatgctaac acttcatcat
     4501 tagccttgaa aagttctaca gttttaagta ttaaatcatc aaagtcaagt gcactatttc
     4561 tttttaaacg gtcttgatat agcgcataaa tatctgcaat cttaaccatt ctattatctg
     4621 ccatattgat atctttaaac tgctttggag tataaagttt gtcttttgct cctgaaattg
     4681 cacttataac tgcttttggt tcaaacactt tatcacttaa atttaattct tttagacagt
     4741 ctttaaccaa tgtaacttgg tctgctgaat cataaattac aaaacttcta ttgtaaccaa
     4801 tcttatttat atcttttctt agtatacgaa cacagcaaga atggaatgta cttatccaca
     4861 tatccttagt ttcaggacct atattttgtt caactctctc tctcatttca tttgcagctt
     4921 tgtttgtaaa tgttatagct aatatatttg gtgcttgtac acctttatct tctataagat
     4981 atgctattct tgttgttaat accttagttt tacctgaacc agcaccagcc agtataagta
     5041 ctggaccttc agtcttttct actgcttctc tttgagcagg atttaatgta tctaaattca
     5101 tatttctcct cctgttaaca gccataaata tattttaatc taaaatatga attacttcaa
     5161 attataatta tgtattatat taatagatta tttccaatat attacaatta aataacattt
     5221 ttccatataa tttatttcat tgtttaataa aaaaaataac cttatgattt ggggaatcat
     5281 aaggcacctt taaggggtct aggttaaggg ttattatata taaatctatt tttttaaaat
     5341 aggtttaggg cttaattatt tatttgtatt aagttctctt tccttccaat acttatacaa
     5401 atcttcttct ttcttaaata agggtaaatt catatttcta tgtactttta ctaaccatgg
     5461 ggattctagg ccagcttgta taatattatt ttcatttata aacacatttt ctgcttttcc
     5521 ttcatcaatc aaaatcccct tatccaatac atatatgtaa tcacatattt catacattaa
     5581 attcatatca tgactggata ttactatttt tatattattt ttatttaatc cctttattat
     5641 atctacaata gacctagtac ttactgggtc taaaccagct gtaggttcat caagtaatac
     5701 aatttcattt tccattgcta taactgatgc tattgccact ctttttttct gtccatagct
     5761 aagaaaatgt actggcctgt ctataaaatc tattccatta acagctacta gagctttgtt
     5821 tattctctct ttaattgttt tttcatccat accaatgttt ctcattgcaa aggctatatc
     5881 atcatatact tttgaataaa aaatttgttt ttctgggtct tggaagacaa tacctacatt
     5941 ttttctaagg ttgtataaac ttctcttatc atattttaac ttttcttctt taaaaagaat
     6001 ttctccagat gtaggcttta atatacccat taaattcata aataatgttg attttcctga
     6061 accatttgaa cctattatac ctataacatt tccctttgaa aaatccatat taatgtttaa
     6121 tagtgcattg gtattttttt catattgata cgttaaatta tttattttaa acatcattat
     6181 cccctactat gtgaaattta ccatcataca attttatgtc taatgatata cacatatcat
     6241 cataccttgt cataagtctt ttgtacagca tacttccaag aatacctaag gatttatatg
     6301 aagtttttaa atttatatat ccaaatctta gctcttgtga cttgtatatt tctgaaaatt
     6361 cttctaaaaa tatgaatata aacctatata ttaacattga taactcgaca aaagtgtcag
     6421 gtaaatgaag ttttttaaaa aagaatatta attgattaaa aggtgttgta agtatacaaa
     6481 aatacacaca agtcaaacaa gacatcgctc taaataacac atgaatagac atgttaatag
     6541 acgcctttga tattcctaca ttaaaactaa aaaattcaaa actatataat aaatctgctt
     6601 tattaaaaga tatatttaca agagttattc ctatactaag aaataaaaag tacattggta
     6661 ttctaagtaa ttttaaataa ttttttaaat ctattccagc cacacaaaca accaaaatac
     6721 tcattaaaat cataattcca cttaaaataa atatattttg tattaccata gaagcaatca
     6781 gaaaaattac tcctatggct acttttttgt ttggatttac tttactcaat ctatttgtat
     6841 atgcatattt atcaattata agcatgatta acttctcttt cctttttgaa gacctaatat
     6901 gtatcctatt acaccagccc ctaaagctgc ttgtgcagag aataataaac tttctatttc
     6961 tccacttggt ggctcatatg gactgctaaa ccatggtttg taatttggat ttatcttagt
     7021 aatttcactt tcagcttgac catctgctcc tccatattca gcacctgagt tgacaagtaa
     7081 tgggaatata ataagagcta ctactaataa aagtaataat atgttagttt ttgtttttgt
     7141 tttagcactc attagcttta actcctttat cattattttc tagtatgctt ttttctccgt
     7201 tttctgtaat taaattatat acaattacag taagtatacc ttctgctatt gctattggta
     7261 tttgagtcat aaagaaaatt cctaaaaatt taattgctga agccattacc ccacctgatg
     7321 ggtctgggaa agccagtgct aattgtattg aagttattgt atatgtggct aagtctccta
     7381 ttgctgctgc aagaaatact ggaatagcat tatttccatc ttttttcttt aaagccttaa
     7441 atattaggaa tgatacgatt ggccctatta tcgccattga aaaagcatta gctcctaaag
     7501 tagttattcc tccatgtgct aataacaatg cttggaatat taaaactata gttccaagaa
     7561 caaacattac gcttggtcca aacattattg ctccaagacc tacaccagta ggatgtgaac
     7621 aacttcctgt tactgaaggt atttttagtg ctgataatac aaacacaaat gctccacata
     7681 aagctaataa tactttcttt ttagggtctt gctttactat tttacctatt gattttaatc
     7741 cgaataagaa aaatggtata aatataactc cccatgctat agaccatttt actggtaagt
     7801 aaccttccat tatatgcatt gcatttgatg taactggagt taaaatgatt aacataagtg
     7861 cagctataac ccctaattta atattctgtt tcatcttagt atccctctct ccctttctaa
     7921 taattaaaac ataataatac atgtctgatt tatttaataa aataaaaaag cctaactcga
     7981 tggttaggct tctaattttc cacaatctaa atacaaacac ataaaacaaa catatctgta
     8041 taattattat aagaaacttt ctccatcccc gaagaaatta ctttaatatt ttaggcaggt
     8101 ctcctgactt agcttcatcc tactcctttt ccttcccatg agatataaaa aatatcatca
     8161 tagtggctaa caaaagtttc gtctgcatca cagtagcggg ggctgtaaag gaatttaacc
     8221 tttttcccta ttaatcttgc ttaaagaacc tataatatta tatatttaat ttttaaatta
     8281 ttcttaaatc attttctata taaatcattg tatacctttt ctgtgaaaat ttctacattt
     8341 tttataaatt ttattcattt ttatattttt atgtatataa attctttttt gtaagtttat
     8401 taatttctaa ttatcttctt taaatacatt gaaactacat cagaaaatct agttatatct
     8461 cttgaatata taaaatcatt tccatatatt aatctttcag cttcaagttc tgattctttt
     8521 cctgtaaata ctcctaatac taatatattt tgctttctag cttttctcac ttcattggct
     8581 gtatctctca aaccaactat acccctataa gccttttctc ctcttaatgt tctctcacta
     8641 ctttttccta tctttacatc atttggtctt ccatcgctga gaactatcag gattttattt
     8701 tcttcatctc tatttattag accactacat atagatttta ttgccaaacc atctctatta
     8761 ttaccagcac aaaaatattc aaatatattt tcactatttt ttatactatc atcataatct
     8821 ttaaatcttt ttaatattgt atagtctaaa aaactagaaa atcccatcac tctatttggt
     8881 atgccaactt ctgttagagc atttgcaatt atgtaagctt gaattgccac atttccctga
     8941 tttctacttt gagagccact tgcatccaat aatatatcaa taacgtattt ccctttttca
     9001 ttttctatat ctttataaaa tattttatta ttattacttc taccaactct ccaagctcta
     9061 ttggctaata tagtaccaca atcagaatat actctacttt tagcattttc ttctattaaa
     9121 attcttgaca gactttcttt taatctcttt atttgctgtc tatacattct agcatgttct
     9181 ctaaattttc ctaaattatt ttctttttgt cttgttacat attttagttg aaatacatta
     9241 ttacactcac ttctaagaac tccatctgta aagtgtattc tacaaccttc atgaacattt
     9301 ctacaatttt gtgtctcaat ttttttaatt tcacctttac tcaaataagt ttttccataa
     9361 taatgttcta tttttgaata tatcttattt gcagtgtctt catcaacata tataactcgg
     9421 tctgctgaat tgctacattt agaatcatca aaatccccta caccttctac aagcatggat
     9481 gaagatattg aatctatatc actttcaata atattttctt cttcatcact ataaagttct
     9541 tcatacatga aatcagcaaa tgtatcaaaa tttacttcta cactttctac attattttca
     9601 tcaataagac tattttcttc tccatttaat atgtattcaa aataagttaa atatataaca
     9661 tctaatgctt ttaaaatctc cataatatct tgattggtat ctatatttct tatatcatta
     9721 actattcttc tagtcatact atctaatgct gggtgcttgt ccatactata aagtacaaat
     9781 gtgtatttaa ttttatccat aatattatca ttgtgtattt tggtaaaacg tgaaacaata
     9841 tctttataag cattccttct tatgtcttct atccctggcc tgtctttaat gaccttttct
     9901 tcaactattg tatttaatat aacttgaatt agacctagta taacatcttt gttgtatcct
     9961 tttcttattc tatttgtaag atatttttta actatatccc aatctacata ctttcttcta
    10021 gcacctgcaa ttattgcgaa atatagacct atttcttttg aagagtaatc tttttctgat
    10081 atatctatac tttcattgta atcaccagct attgtccatg ataggttatt agctctattt
    10141 tcaaattcat aatcatcata tatccatttc ataatctcac ctatattaaa tatgacttat
    10201 tggaaacaca tctatactct cccatttatt aggtattcta gttttaatta catctccaac
    10261 catttctttc tcatatacat caaaagtctt tcctgtaagt cccatattaa ttgcaagagt
    10321 tggttttaat cctcttctta tagtcttaag agatgccata agaccacgta aatcaatagc
    10381 tttactagat atctctccat tttgagactt caattgtaaa tctaaaaata ttcctgcaaa
    10441 gtgtattaat ttttcttcat cagcatctga aaattcattt tttaaaatca tcattaactt
    10501 atcttcttct ataggaggaa tatctattac cataaatcta gataccagtg cttcattaag
    10561 ttcttttgtt cctgcatatt cataattcat agtcccaata aatcttgttg ctggatgtag
    10621 attgactctc tcatacccag gtacatcaat tattcttcta tagtctaaag ctgaatgtac
    10681 cacaactata gcatcatttt ttgccatatt aatttcatca aacaccccaa aacctccatt
    10741 aatagcacac tcataaactg agcctcttct aagtttaact tcattgtcta taaatgtatc
    10801 tgtacctata agtgttgaac tgtctgtatt tatatgaaat gatgtattcc actgaggtct
    10861 attaaatatt tcccctagat tatcagcaag taagtttttt cctgttgcct ttggtcccga
    10921 taataatata ttttcttctt ctaaaatagc tgctatacac atagacaaga tatctttacc
    10981 ataaaaataa gttttagact ttgttactct gtattctaaa tctttttcta aaccataata
    11041 atttctaaaa tacagtacat cttcaataag tttttcatct accccttgca cccttagatt
    11101 atctattata tccatatttt tacccctttt atataaatag tatttgtttc atttcttatc
    11161 accattttag cataaaagga tataagctaa aattgatttt ttaatctccc cattttaagt
    11221 aaaaccatgc accattttat cactacaaaa ttaagagtac tacttactga tatttcttga
    11281 ttttgttcgt ctatacgtat ataatatatg ctgataaatt atgaggaaag gatgattgaa
    11341 atatggatgc ccagaagtag caaaaaaatg gggtatttct gaaagaagag tacaaaaact
    11401 atgtgaagaa agtcgcatac caggagtttc aaaactcggg tatatgtggc tgataccaaa
    11461 gaacgcagaa aagcctgttg atggtagaac aaaaagaaga aaggaagtac aatatgaata
    11521 gcgttttgat tatagatgat gacaaagaac tttgtgctct tatgaaaaaa tgtgttgagc
    11581 aagaaaattt atctgctatt actgcacatt gtggtgcaga aggtctacat ttggtcgata
    11641 aaaatagaca cacactctct cttgtaattt tggacataat gatgccagat atagacggtt
    11701 ttcaagttct gaaaaaaatt agagaaacaa gtaatattcc agtaattatg cttactgcta
    11761 aaaatgacga ggatgataaa gtttccggac tacgtttagg tgctgacgat tacctaacaa
    11821 aaccgttcag cataaacgaa cttatggctc gtgtcaattc tcttattcgt cggtatacta
    11881 tgttaaaccc tgcttttata acagacacag attgcataat aataaatggc atgattattg
    11941 acaagacaaa ccgaattgtt tctgtcaata atattcctgt tcaacttaca agcaaagaat
    12001 ttgatttact tgcttttctg gcttctaata agggacgggt gtttaccaaa aaacagattt
    12061 atacacaagt atgggaagaa gaatatgctt ttgacgatag taacatcatg tctttcatca
    12121 gtaaattgag aaaaaagatt gaaccagacc ccaaccatcc attttatatt ttgacagttc
    12181 gtggtgtcgg ttatcgtttt aataaggagg cttaacatga atacaagtgt ctatctgctt
    12241 ttgatattgg ttcttagcct gattattata gcgtaccttg tttctgtcct gctacgtgtc
    12301 cgaatacaac ttacacttat aaaagatgct ttagaggata taaaaaatgg aaaccttaat
    12361 cgacgtattt taacagatga aaacgacatt acaaaacaaa tttgctatga tattaacgaa
    12421 atagcaatca atagccaatt tcaacttatt cagcaaaaac aatcagaaca agcctacaaa
    12481 cagctaatga caagtctctc ccatgatgta aaaactccac ttgcttcttt ggtcggttat
    12541 ttggaagcag tagaaagtaa aattgttgta ggagaggaaa aagacgagta tatccatgtt
    12601 gcgtctaata aggctcatta cttaaagaat tttgtagaaa atctatttga atgggtaaaa
    12661 ttggattcta aggaacaagt ttttcatttt gatatttttg acttgaatga attatcccgt
    12721 aatattatat ctgattggat acctgtttta gaaagcagtc attttgaata tgaatttgat
    12781 ataccagaaa tagagtactt cttacgtata gacgcaaatg catatacccg tatcattaat
    12841 aacctattac aaaatattat tacccatagt agtggcaaca aaatgacatt gagaattttt
    12901 gaaaacaaag agcaagctca aattataata acagataatg ggaaaggtat atcttcagac
    12961 aatctcccac atatttttga aaggttgtac caatgcgacc attcacgagc ttcaaaggga
    13021 aatggtttag gcttggcgat tgcaaaggaa cttattaacg ctcataaggg aaatattacc
    13081 gccaacagca ctcccggtat gggaacagaa tttacaatat tgcttcctaa agccctgtaa
    13141 aagtacgagg ctttcttact ctaaaacaag ataaaagcaa gattatggca aggttttggc
    13201 aaggttcatg ttttataatt ctaattgtag ttgattttga cgttgtatca actatctttt
    13261 gtagaaacaa atttattaaa agtgaggaaa ttatatatga atgattttgt gattgaaaca
    13321 aagcaactta caaaaattta tgggaatcaa acagtagttg acaaagtcaa tctccatgca
    13381 aaaaaaggcc gaatatatgg tctgttagga cgcaacggag ctgggaaaac cacaattatg
    13441 aaaatgattt taggattgac ttcaatcacg tatggcgagg tagatgtatt tggagagaat
    13501 attaagggac gtgaaaaaca agtatatccc cgtatcggtg caattatcga aacgccagga
    13561 ttttatccta atctgacagg aacggagaac ttggagattt ttgcaaaact gcgtggtaca
    13621 gccgccccta attctgtaaa aagagcattg gaaattgtag gcttacctta taaaaataaa
    13681 aagctgttta gtgaatattc acttggcatg aaacagcgac ttggtattgc caacgctatc
    13741 ctgcatgacc cagaactgtt agttttagat gagccaacca atggtcttga ccctattggt
    13801 attgcggaga tgagaaagtt tattagggac ttgagcgttg agcatggaaa gacaattctt
    13861 atttccagtc atattctttc agaaatctca ttgttggctg atgatattgg aattatcgac
    13921 cacggtgttc ttttggaaga aagtagtatg agtgaactag aaaagaaaaa cagtaaatat
    13981 atcctgctac aagtttcaga tattccgaag acatcactta ttttagagcg tcaatttaac
    14041 acgaaggatt attccgttca agatgactac acgttacacc tttataacac taatctggat
    14101 atgggtgaaa tcaataaagc acttgtaatg cagaatgtaa ctgttattag ttctcaactt
    14161 tgtaatgata ctttagagga ctactttaaa aaaatcacag gaggagaggg cattgcttaa
    14221 acttattcaa acagaatttc ttaaactgcg tcgtaggaaa cttatttggc tgatgttgtt
    14281 gtctgctctc attatgccgt ttttcgcact actatacttc aattattttg gtaaaacagg
    14341 tgttgagcca ataaagtttt ataaatggtc tgcatttggt tatacacttt ggattatttt
    14401 gcctgttgtt ttgggtatat tttgcaccat gcttatacac gaagaaaacc agtatgatat
    14461 gctcaaacag ctttggattg tacctattag taaaatggga tactttttta gtaaattttt
    14521 cgttgttttg atttactcta tttgttttat gctgattaca gccgttgctt ctgtgttatt
    14581 tagtgtactt tctggatatg tcgtatttag ctgggcaagc attttatatt tgttgaaaaa
    14641 atgtttagaa attggtgtaa tcactgcttt tgtaatgttg ccgattttgg caatcgctac
    14701 atctcaaaaa ggatacattc tcccaatttg tatcacattg gtatatgcct tttccggttt
    14761 tgttataatg acaataaata tgtatttaca cccattatcc agtatgggag ttattatcat
    14821 gagaaataaa gacattccag gtcttatatt ttcacaggaa attaatgtcc cattagcatt
    14881 tctttgtatt tgtatttgga gtattgtatc agtattgttt gcaaacactg cactaggaag
    14941 aagaaagtga ggtgtagata atgtggaaat tactttgggc tgaatgtcaa aaaattcgtc
    15001 gttcaaaaat tgtttggatt acagtttttg catccattat gatagcagtc atagtttttg
    15061 caggagggca ggatgtatat aatgacccag atttacatta tggcttaaag agcgtttatg
    15121 acggttcacg gtatatagac aatgcaggtt ggtatatgga cgcagtacaa ccttggtcaa
    15181 ctttttttgt tcttcctgct gtcattgccc tattaggaag ctatattatt tgtcgtgaag
    15241 aagaggagga cactattaaa tccctgcgtc ttattcccat aaatgaaaca aaattaacca
    15301 tagcaaaaat gattattact tttatattca gtatacttct ttatttgtta ctctttacta
    15361 taacattttt gactgaatcc gttttacatt tttccgattt atcgacaaaa ctggttttaa
    15421 gttgcatgaa agagtatttt cttgatggca taggtgtatt ctttgcaatt tctcccatta
    15481 ttgccttggt atcgcgcatg aaaaaaggat attggcttgc attagtattc acagaagttt
    15541 attctattgc tggactattt gcgggtatgt caaatgtctt acaaaccttt tttcctattg
    15601 cggcaatatt taatatttct ggatactata taactactgg agaaaaaatt atggggagta
    15661 tcataagttt attactttgt gcctgccttt ctgcatttat acttaaaggg ctaaaacaca
    15721 atgaaaaaaa ttgaaatagg tatatcaaaa tgaaaaagat aaaaaaactg attattctaa
    15781 ttgtattctt gtttcttttt ggcatgttac actgttatac tgaatggaaa ttcaacaata
    15841 acccacctaa aggggtaata gaaagaataa atgaatggac tgataagatt ggactggatt
    15901 agtaacttat gttaattata gtgaatgtaa tattagcaag ttattgtttc gtattttaat
    15961 actataactt taaatatttg gttttaatct tccaaacgaa tataaaaaaa ctgtcacaga
    16021 ggcaacatat ttttgaatat ttataaagtg gtagttttga ttttcaaagc tgccgccttt
    16081 tcttctatat aagcaaactt atcctcaaca aagtgtaaaa catggtacat tttaagaaaa
    16141 aagtaccaca gacacaagca ataaaagaaa cgccgagaac ctacaaaaac gtagtgctta
    16201 tgcagattta cgacgccttc tattttctca accgtcttaa tgaccttgta caaaagaaat
    16261 ttttctaata ttttttataa tcttatcttg tgatgttttt tatgtataaa tgacttaata
    16321 acaaatccaa taaaaattat ggatattggt ataattagaa cgaggaattt ataatcatta
    16381 taatgtgaca ttattcttac ccaactctca gaaaaaatat atcctatact gattaatgaa
    16441 gtattccata tggttattcc cacgatagat gatattacaa aagttataat attttgacct
    16501 gctatacctg ctataaaaga tatgtatgtt ctacataaag ggattaatct acatacacaa
    16561 acagaaatag aagagtattt gttaaaataa tcttgagatg caaatattcc tttctttgcc
    16621 tttggacata tctctattat tttatttatg atagatttac ctccccaatt tcccactgta
    16681 taacaaaata tcgaaccaag tatacctgca attatactta aaattaaaat tgtcagaaat
    16741 ccaaaatgat ttcttgcagc aattgctcca cataaaggta aaacaacttc gctaggtaat
    16801 ggaaaacaag catactcaat cataattaat acaaatacag agattaatcc atattgtaaa
    16861 ataaaactat tgattacaga cacttactta tctatctcct ttcttattta aaggttttaa
    16921 gggtacatgt tctaaggatt ctcaccctat atttaaagaa tcaatctctt taaactatta
    16981 tatgtattta cacaaagcat ttataacata ctttaaaaat agtaccttaa aataagaaac
    17041 ttaataaata aaaaaagatt acgtggctac gtcctactct cccaggcag
//
LOCUS       DAYAOO010000233        11814 bp    DNA     linear   BCT 12-OCT-2024
DEFINITION  TPA_asm: Clostridioides difficile isolate ST8-SSI-h139-18
            SAMN40601845-rid21577343.guided.112, whole genome shotgun sequence.
ACCESSION   DAYAOO010000233 DAYAOO010000000
VERSION     DAYAOO010000233.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN40601845
            Sequence Read Archive: SRR28438827
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 11814)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11814)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-MAY-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-MAY-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002157583.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002157583.1
            Genome Coverage       :: 163x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/11/2024 16:19:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 4,038
            CDSs (total)                      :: 3,963
            Genes (coding)                    :: 3,930
            CDSs (with protein)               :: 3,930
            Genes (RNA)                       :: 75
            rRNAs                             :: 6, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 60
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 33
            CDSs (without protein)            :: 33
            Pseudo Genes (ambiguous residues) :: 0 of 33
            Pseudo Genes (frameshifted)       :: 7 of 33
            Pseudo Genes (incomplete)         :: 25 of 33
            Pseudo Genes (internal stop)      :: 11 of 33
            Pseudo Genes (multiple problems)  :: 8 of 33
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11814
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN40601845-rid21577343.guided.112"
                     /isolate="ST8-SSI-h139-18"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Denmark"
                     /collection_date="2018"
                     /collected_by="Statens Serum Institute"
     gene            158..1564
                     /locus_tag="ACGI5H_004005"
     CDS             158..1564
                     /locus_tag="ACGI5H_004005"
                     /EC_number="3.2.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860965.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016798 - hydrolase activity, acting on
                     glycosyl bonds [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
                     /protein_id="HFG9699637.1"
                     /translation="MNTGFPKDFLWGASSSAFQVEGAWDKDNKGKTVADYNSFKKSHL
                     QADTKVASDFYHNYEEDIELMKELGMKTYRFSISWARIIPDGEGEINQKGLEFYNKII
                     DKLIECDIEPFVTLYHFDLPFKLVEKYNGWESRETVYAFERFAKICFKHFGDRVKYWQ
                     PHNEQNLIVRVEERINIYDETDSWKIDKMRAQMDYNLCLAHALAVNACHEMIKESKIG
                     AAVSSSVTYPLTSKPEDVYAARMNDNFKVYYMLDMHHYGEYPGYYMKYLEKRNIVPHM
                     EDGDKEILKKAKMDFIAVNYYRTNCAEALPEDSQHPFGLREGTVDFSMYGLFKMSMNP
                     NLEASEYGAAIDPSGLRVALNEYWQRYHLPVIITENGLGAKDILEDGKIHDDYRIDYL
                     RSHINACKLAIEDGVEMIGYCPWSFTDLLSSSQGFNKRYGLVYINRTDHEVLDLKRIK
                     KDSFYWYKEVIENNGIVK"
     gene            1592..2440
                     /locus_tag="ACGI5H_004006"
     CDS             1592..2440
                     /locus_tag="ACGI5H_004006"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454252.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HFG9699638.1"
                     /translation="MYITKVLNNSLLLAKDDNDEEIILMGKGIGHNYKAGSELNKKDI
                     EKIFVLHDENIKKSIIQLATEIDAEYFGIAQMIIAYGIEKYNLKLMNHIYLALTDHIA
                     FAVRRFKEGIMIENHYLFEIKEFNPKEYDIGKYAITVFKEVLGLDLPEEEIGNIAGHF
                     INAQQDNPYSDRNKRSAKIVNAILQIVHYHFSIVYNKESFYYRRFVMHLKAFSQRFLA
                     NEPSREKIDFIYEQVQKNCKEEYECVKKVGAYMYKEYSRELPRQEELYLMIHIHKILG
                     ELCENS"
     gene            3101..3793
                     /locus_tag="ACGI5H_004007"
     CDS             3101..3793
                     /locus_tag="ACGI5H_004007"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728879.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000156 - phosphorelay response regulator
                     activity [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HFG9699639.1"
                     /translation="MNKVLIIDDDKDLCILLKKSISIEQIEANYCHSGRDGLVELSKQ
                     DYQLVVLDVMMPGMDGFETMEQIRKYSSIPILMLTSKSDNYSKVHGLRAGADDYLTKP
                     FEITEFTARVLSLIRRYTRFNPKNEEPQQLSFKGLLIDLDQHTVTTNGEPMLLPPKEF
                     GVLLYCARHQGKILTKQQIYEAVWGEPYVYDDSNIMAIISRLRKKIELDPSSPIYLQT
                     IKGIGYQFNTEV"
     gene            3790..4725
                     /locus_tag="ACGI5H_004008"
     CDS             3790..4725
                     /locus_tag="ACGI5H_004008"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418502.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing sensor histidine kinase"
                     /protein_id="HFG9699640.1"
                     /translation="MKMDEQTIILFLLLLSIGLLFLSIFAFSKLGHIYKRLKDIEEIL
                     ADVQIGDENRKILIKPCDVMAPLVYQLNEIVYDYENKLLSLKKSDKASKQLMTSLSHD
                     VRTPLTTLIGYLDAVHSGIVIEQEREEYLEIARRRAYDLKDYIDVLFDWFRLNSDEFT
                     LSIESVEIAELSRNILKDWIPIFHEKKLNFEIDIPENRLMVNLDPDGYSRVVNNLVQN
                     VLAHSKARQIKITMSEDSRMVLLRVEDDGVGIARENLPHIFERLYKCDKGRSEKGSGL
                     GLSIVSQMVERMGGQVSVESEIGKYTVFTVSLPLI"
     gene            4873..5796
                     /locus_tag="ACGI5H_004009"
     CDS             4873..5796
                     /locus_tag="ACGI5H_004009"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019639192.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HFG9699641.1"
                     /translation="MNNLIIETKNLTKQYGAQKSVSNLNIHVQKGRIYGLLGRNGAGK
                     TTTMKMLLGLTKPTTGEIKIFGQDIHNNEKKLLPRIGCLIESPGFYPNLTGTENLKIF
                     ARLRGIPKKNAVESALDVVGLPNNDKKLFSQYSLGMKQRLAIALAIMHDPQLLILDEP
                     INGLDPIGIAEVRTFIRDLCTERGKTILISSHILSEIALLADDIGIIDHGILLEEESL
                     AQLEEKNSKYIHFAVSDAAQAARLLETQLNLKNFKVADNYNIMLYDTDVSVAEINRAF
                     ILNNIEVSESHLCEDTLEDYFKKVTGGEGIA"
     gene            5780..6550
                     /locus_tag="ACGI5H_004010"
     CDS             5780..6550
                     /locus_tag="ACGI5H_004010"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012816056.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HFG9699642.1"
                     /translation="MKELLDIISCEFSKLKRLKFILISILGACLFPIPATILIAKDNL
                     PFEQLFKLVVNFGYFLLLPIVLSIVASQLFFIERDNDVLKNLATVPVQKGKLALAKLA
                     VLLFISLFYSVAGLGATIIGGFIVGIVEGVAVKLGMSIAFGIMFFVTVLPVVVLIVYF
                     NRSYIFSIILSFVYAIFNFSISLNIINFEPNNPILSVLPAPVIMRWWMAFWGDPTGEY
                     TALRQPYLLSTPACVGILCLITIIAVLLICMIYKKQEN"
     gene            6560..7342
                     /locus_tag="ACGI5H_004011"
     CDS             6560..7342
                     /locus_tag="ACGI5H_004011"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418511.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HFG9699643.1"
                     /translation="MLDIITTEFQKIKRYNILWIGVVAVLFSALLAVFQVVSSHGSDP
                     LTYESFANGVIWNNFSLSFPFGITLIGGYLINREYTDQTLKNILTVPISLRKLLVGKL
                     IAVGGITVLLSLFSFLCTFILGLLFCNINISVTLVVKSLVQILSVNLYCYVAVLPIIA
                     YFGRKQNAFLTGVGIAFVYGFCGVFVAGRNLTDFYPITAGLGLVGYNNGAGTVYQPLI
                     GAMTLIVILILTTILLVFTPNYDKVMTISKKKGIKHKKYSHK"
     gene            7719..8255
                     /gene="rbr"
                     /locus_tag="ACGI5H_004012"
     CDS             7719..8255
                     /gene="rbr"
                     /locus_tag="ACGI5H_004012"
                     /EC_number="1.11.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418513.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0009055 - electron transfer activity
                     [Evidence IEA];
                     GO_function: GO:0016692 - NADH peroxidase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="rubrerythrin"
                     /protein_id="HFG9699644.1"
                     /translation="MNLKGTKTEKNLMAGFAGESEARNKYTYYASKARKEGYNQIAAI
                     FEETANNEKEHAKLWFKLLHDGMPSTEENLKDAAAGENYEWTDMYAKFAKEAREEGFD
                     KIAYLFEAVGKIEKEHEERYLKLLENLNEGKIFKRDEEVVWQCQNCGHVYVGTEAPEK
                     CPVCDHPKAYFNIKAENY"
     gene            8287..8676
                     /locus_tag="ACGI5H_004013"
     CDS             8287..8676
                     /locus_tag="ACGI5H_004013"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905140.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional repressor"
                     /protein_id="HFG9699645.1"
                     /translation="MKFSKQRELILNEILNNPVHPTADYLYENLKKDNPNLSLGTVYR
                     NLAQLTEHGFIRKVSIPGYPDRFDGRIDNHYHIICEVCGEVYDLESEVLNNLQELISE
                     ETDIKITSYNISFKGICNNCKRCSQVG"
     gene            8713..9099
                     /locus_tag="ACGI5H_004014"
     CDS             8713..9099
                     /locus_tag="ACGI5H_004014"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004453642.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005506 - iron ion binding [Evidence IEA];
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="desulfoferrodoxin family protein"
                     /protein_id="HFG9699646.1"
                     /translation="MCSEQKFFICETCGNLVGMIQSGGVPIFCCGKPMKELVPNTTDA
                     AVEKHVPVIEVDGNNVTVKVSSTTHPMTKEHHIAWVYLMTEQGGQRKCLAVDGEPVVK
                     FALNDDDKVISAYAYCNLHGLWKAEL"
     gene            9226..10668
                     /locus_tag="ACGI5H_004015"
     CDS             9226..10668
                     /locus_tag="ACGI5H_004015"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418516.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0015930 - glutamate synthase activity
                     [Evidence IEA];
                     GO_function: GO:0016638 - oxidoreductase activity, acting
                     on the CH-NH2 group of donors [Evidence IEA];
                     GO_process: GO:0006537 - glutamate biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate synthase-related protein"
                     /protein_id="HFG9699647.1"
                     /translation="MSIYKCSVCGYIYDESKNDKTWDELSEDWECPVCTKGRSYFGKI
                     STVYYEEDEKIAEDIVEDESKLNTEKEGDLNYLSTYLRRDDEVEKHMDIIHEMAVTGK
                     SIIEPMRTKLPVISWDDILIMGAQLNPLPLNEHDEVNTTTIIGKKAKKPMIIENPVYI
                     SHMSFGALSKELKIALAKGAAQNKTAMCSGEGGILPEEKEASYKYIFEYVPNKYSVTE
                     ENLKNSDAIEIKIGQGTKPGMGGHLPGEKVTEEIAKVRNKPVGQDVISPSCFEEIQSK
                     EDLKKLVDELREVSEGRPIGVKISAGHIEKDMEFIAYAKPDFVTIDGRGGATGASPKL
                     LKDATSIPTIFALYRARKYIDTHGLDIDLVITGGLRISTDFAKAIAMGADAVAIASSA
                     LMAAACQQYRICGSGKCPVGVATQDEELRKRLHIENSANRVANFLNVSLEELKTFARI
                     SGHKDIHDLSVDDLYTVNSEISNYTNIQHV"
     gene            10965..11780
                     /locus_tag="ACGI5H_004016"
     CDS             10965..11780
                     /locus_tag="ACGI5H_004016"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728724.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HFG9699648.1"
                     /translation="MERLKIQVLVDNNTYIDRYFVGEPAVSYYIEIDGNRILFDSGYS
                     DVFISNAEKLNIDLGNLTHVVFSHGHNDHTRGIQFLENRYDLSTVELISHPNCFIPRK
                     HGEKSIGAPFSAEEIKNIFMYNPKDKPFNLSKNCVFLGEIPSINDFEKRAKIGKCKIG
                     DLWEDDYVLDDSAIVCKTDKGIFIVTGCSHSGICNIVEYAKKVCGDDRVIGILGGFHL
                     FELNNRLDSTIQYLDKEEMRMLYPCHCVSFKVKAKMNEILNINEVGVGLTISI"
BASE COUNT         4239 a         1477 c         2256 g         3842 t
ORIGIN      
        1 aatatagagt aagtttattg taatgaattg ttaaagaaaa taattaatat agggtaaatc
       61 tatctcaatg aaataacaaa gaaaagagtt aatatagagt gaacttattg caatgaatca
      121 acaaagaaaa taatcaatat aaaaaggaga aatatttatg aatacaggat ttccaaaaga
      181 ctttttatgg ggagcatcat cttctgcatt tcaagtggaa ggagcttggg ataaagacaa
      241 taaaggaaaa accgtagccg actataattc ttttaaaaag tctcatttac aggcagatac
      301 taaagtcgca tcagactttt accataatta tgaagaagat attgaattaa tgaaagaatt
      361 agggatgaaa acatatcgtt tttcaatttc atgggcaaga ataataccag atggtgaagg
      421 agagataaac cagaaaggtt tagaatttta taataagata atagacaaac tgatagagtg
      481 tgatattgag ccattcgtaa ctttatacca ttttgacctt ccatttaaat tagtagagaa
      541 atataatggt tgggaaagta gagaaactgt ctatgctttt gaaagatttg ctaaaatatg
      601 ctttaagcat tttggagata gggtaaagta ttggcaacct cataatgaac agaatttaat
      661 tgttagagtg gaggagagaa ttaatatata tgatgaaaca gattcatgga agatagataa
      721 aatgcgtgct cagatggatt ataatctttg cttagcacat gcattagcag tcaatgcatg
      781 tcatgagatg ataaaagaaa gtaaaattgg agcagcagta tcatcatctg taacatatcc
      841 tcttacttct aagccagaag atgtatatgc agctagaatg aatgataatt ttaaagtgta
      901 ctatatgctt gatatgcatc attatggaga atatccaggg tattatatga agtatcttga
      961 aaaaagaaat atagttcctc acatggaaga tggggataaa gagatactta aaaaagctaa
     1021 aatggatttt atagctgtaa attattatag gacaaattgt gcagaagctt tacctgaaga
     1081 ttcacaacat ccatttggat taagagaagg aactgttgat tttagtatgt atggactatt
     1141 taaaatgtca atgaatccta acttagaggc ttctgagtat ggagcagcaa tagacccatc
     1201 aggtcttaga gttgccttaa atgaatattg gcaaagatat cacttacctg ttataataac
     1261 agaaaatggt ctaggagcta aagatatatt agaagatgga aaaattcatg atgactatcg
     1321 tatagactat ttaagaagtc atataaatgc atgtaaacta gctattgaag atggtgtaga
     1381 gatgattgga tattgtccat ggtcatttac agacctttta agttcttctc aaggttttaa
     1441 taagcgttat ggacttgttt atataaatag aactgaccat gaagttttag atttaaaaag
     1501 aatcaagaaa gatagttttt actggtataa agaagttata gagaacaatg gaatagtaaa
     1561 ataaacataa atatatattg agggttttag tatgtacatt acaaaggtat taaataattc
     1621 gttgctactt gcaaaggatg ataatgatga agaaataata ttgatgggga aaggcattgg
     1681 ccataattat aaggccgggt ctgagttaaa taaaaaagat atagaaaaga tttttgttct
     1741 tcatgatgaa aatataaaaa agagtattat acaattggca acagaaatag atgcagaata
     1801 ttttggtata gctcaaatga taattgcata tggaatagaa aaatataact taaaacttat
     1861 gaaccatata tatttggcct taactgacca cattgccttt gcagtgagac gttttaaaga
     1921 aggtataatg attgaaaatc actatttgtt cgaaatcaag gaatttaatc caaaagagta
     1981 tgatatagga aaatatgcta ttactgtttt taaggaggtt cttggtttag acctaccaga
     2041 agaagagatt ggtaatatag caggccattt tataaatgca caacaagata atccttatag
     2101 tgatagaaat aagagaagtg ctaaaattgt aaatgctatt ttgcaaatag ttcattatca
     2161 cttttctatt gtatataata aagagtcatt ttattatagg agatttgtaa tgcatctaaa
     2221 ggccttttca caaagatttc tggctaatga accatcaaga gaaaaaatag attttatata
     2281 tgagcaagtt caaaaaaatt gtaaggaaga gtatgaatgt gtgaaaaagg taggagctta
     2341 tatgtataag gaatactcca gagaattacc aagacaagag gagttatatt tgatgattca
     2401 tattcataag attttaggag aattatgcga aaatagttag aatatcttaa tatgctagta
     2461 atattataaa aaattaaaaa ttaactgcac tttaaatatg aataattgca ttacttaagg
     2521 gggttgtctt aaaattgatt tttttaatta aatttgaagc tcaactcctt ttttaaacct
     2581 ttatatcatt acaactttaa tgtttatacg actgtacttt agatgtatat ctacttttta
     2641 catttctcaa catgcaaacc taccattttt tgcagtatgt taattgaaat aaaccattga
     2701 gttaacccta aatttattct ggacttatag gaatagttcc aaagatactt taaaatattt
     2761 tctggaataa ttgcttattt cacatatgtt ttattgtgat gttttgattt aataaattct
     2821 tcaactctgt atatagtaaa tgtattatca tgtttgtttt attcaagcac acttataata
     2881 cgcttgattt tttcacaatg atgaaatata ctaatgggtg ttataggtat aagaatcgca
     2941 ttacacttga agaagtaagt gataaatgag gtataaatcc tcatatgata aactactatt
     3001 tcattgagga acatattcta agtgatgtca agatactaca atatgactaa attcctagtg
     3061 ataaaaaagt ctacgaatga gtgtagaaag gggaactaag atgaataaag ttttaattat
     3121 agatgatgat aaagatcttt gtattttgtt aaaaaagagt atttcaattg aacagattga
     3181 agcaaactat tgccattctg ggagagatgg actggttgaa ctttcaaaac aagattatca
     3241 gttagtagtt ctagatgtga tgatgccagg tatggatggt tttgaaacta tggaacaaat
     3301 acgaaaatat agcagtattc ccatcttaat gctgacatca aaaagcgata attacagcaa
     3361 agtgcatgga ttgcgagctg gtgcagatga ctatctaacc aaaccatttg aaattacaga
     3421 atttactgct cgtgtactgt ctttaatccg acgttacacc cgttttaatc caaaaaatga
     3481 ggagccacag caactttctt tcaaaggttt gttgattgac cttgaccagc atacagttac
     3541 taccaatggc gaacctatgt tgcttccacc caaggaattt ggtgtacttc tttactgtgc
     3601 aaggcatcag ggtaagattt tgacaaaaca gcagatttat gaagccgtgt ggggtgagcc
     3661 atatgtatat gatgacagca atatcatggc tattatcagt cgcctaagaa aaaaaattga
     3721 actagaccca tcatctccca tctatttgca aacaataaaa ggaattgggt atcaattcaa
     3781 cacggaggta tgaaaatgga tgaacaaacg ataattcttt tcttactctt gctgtcgatt
     3841 ggtctacttt ttctttccat atttgctttt tccaagcttg ggcatattta caagcgccta
     3901 aaagatatag aggagatact ggctgatgta caaattggag acgaaaatcg taaaatacta
     3961 attaagccat gtgatgttat ggctccattg gtttatcagc ttaatgagat tgtctacgat
     4021 tatgaaaata agttactttc tctgaaaaag tcggataaag ctagcaaaca acttatgaca
     4081 agtttatctc atgatgttcg tacaccatta acaactctga ttggttatct ggatgctgta
     4141 cacagtggta tagttatcga acaagagcgg gaggaatacc ttgaaatcgc taggcgtaga
     4201 gcctacgacc tcaaggatta cattgatgtt ctttttgact ggtttcggtt gaactctgat
     4261 gaatttacgc tgtcaataga atctgtggaa attgcagagt tgtcacgcaa tattttgaaa
     4321 gactggattc ctatattcca tgaaaagaaa ctgaattttg aaattgatat tccagaaaat
     4381 cgactaatgg taaacctcga cccagatgga tattcccgtg tggtcaataa tctggttcaa
     4441 aatgttcttg ctcacagtaa ggctcggcaa atcaagatta ccatgagtga ggattccaga
     4501 atggtattac tccgtgttga ggatgatggt gttgggattg ccagagaaaa tttaccacat
     4561 atttttgagc gactgtataa gtgtgataaa ggacgttcag aaaaaggaag tggtcttggt
     4621 ctatctattg tcagtcaaat ggtggagcga atgggtggtc aggtttccgt agaaagtgag
     4681 attggaaagt ataccgtatt tacagtgagc ttaccattaa tataaaattg tttttccccc
     4741 atgtgacatg tatacacatg gggatttttt gtaagttata aagttgcaag gttaatacaa
     4801 ggttgttgca aggttaatgt aagattgagg tggtatgata actttaataa acaaaggagg
     4861 cttttattat ttatgaataa tttaattatt gaaacaaaaa atctcactaa gcaatatggt
     4921 gctcaaaaga gcgtttctaa tttgaatatt cacgttcaga aaggtcgcat ttacggattg
     4981 ctaggaagaa acggtgcggg taagacgaca actatgaaaa tgttattggg tctaacaaaa
     5041 ccaactactg gagaaattaa aatatttggt caggacattc acaataacga gaagaagctt
     5101 cttcctcgaa ttggatgttt gattgaatca ccagggtttt atcctaatct gacaggaaca
     5161 gaaaatctca aaatctttgc aaggcttaga ggaataccaa aaaaaaatgc agtagaatca
     5221 gcactggatg tagtcggttt gccaaacaat gacaaaaagt tattttctca atactctctt
     5281 ggtatgaaac agaggttggc gattgctctt gccattatgc atgacccaca actgttgatt
     5341 ttggacgagc ctatcaatgg acttgatcct attggtattg cagaagtaag aacgtttatt
     5401 cgtgatctct gcacagaacg aggtaaaact attttgattt ccagtcacat tctttctgaa
     5461 attgccttgt tggcagatga cattggcatt attgaccatg gtattttgtt ggaggaagaa
     5521 agtcttgccc aattagaaga aaaaaacagt aaatacatac attttgctgt atctgatgca
     5581 gcacaggcag caaggcttct ggaaacccaa cttaacctga aaaatttcaa agtagcagat
     5641 aattacaata ttatgctata tgatacagat gtttctgttg cagaaataaa tcgtgctttc
     5701 attctaaaca acattgaggt atcagaatct catttatgcg aagatactct tgaagattac
     5761 ttcaagaaag taacaggggg tgaaggaatt gcttgatata atttcatgtg aattttcaaa
     5821 actcaagcgg ttaaaattta tactgatttc tattttaggt gcttgcttat ttccaattcc
     5881 cgcaacaatt ttgattgcaa aggacaactt gccctttgag caattgttca aattagttgt
     5941 caattttgga tattttttgc tattaccaat tgtattaagt attgttgcta gccaactatt
     6001 ttttatagaa agagataatg atgtattaaa aaatcttgca acagtgccag tgcaaaaagg
     6061 aaaactggct ctggcaaaat tggctgtgtt gctgtttata tcattgttct actctgttgc
     6121 agggttagga gctactatca ttggaggttt cattgttgga atagtagagg gggttgctgt
     6181 aaaattagga atgagcattg cttttggaat tatgtttttt gttactgtac ttcctgttgt
     6241 ggtactcatt gtatatttca atcgcagcta tattttttct attatacttt cttttgtata
     6301 tgctattttc aattttagta tatccttaaa tattatcaat tttgaaccaa ataacccaat
     6361 attaagtgta ttacctgctc ctgttataat gcgttggtgg atggcatttt ggggagatcc
     6421 cactggcgaa tacacggcac ttagacagcc atatttgctc tcaactcctg cttgtgtagg
     6481 tattttatgt ttgataacca ttatagcagt cctgctgatt tgtatgatat acaaaaagca
     6541 ggagaattag gaggtatcta tgcttgatat aattactaca gaatttcaaa aaataaaaag
     6601 atataatatt ctatggattg gtgttgttgc tgttctgttt tcagcactat tggcagtttt
     6661 tcaggttgta agttcacacg gcagtgaccc tctaacgtat gagagctttg caaacggagt
     6721 tatctggaat aatttcagtc ttagttttcc atttgggatt acacttattg gaggatatct
     6781 tattaaccgt gaatatacag accaaacctt aaaaaacatc ctaactgttc ctatttcatt
     6841 acgcaaattg ctagtgggaa aattaattgc ggttggagga attactgtat tgttaagtct
     6901 tttcagcttc ttatgcacat ttattttggg gttgttgttt tgcaatatca atatatctgt
     6961 tacactcgtt gtaaaatcct tagttcagat tttgtctgtt aatctgtatt gttatgttgc
     7021 tgttttgccg attattgctt attttggtcg taaacaaaat gcatttctga cgggtgtagg
     7081 gattgcattt gtatacggtt tttgtggtgt gtttgttgct ggaagaaatc tgacagactt
     7141 ttatccaatc acagcaggtc ttggtctagt tggatacaac aatggtgctg gtactgttta
     7201 tcagccactt atcggtgcta tgactttgat tgtaattcta atcttgacaa ctattctact
     7261 tgtatttaca cctaattatg ataaagttat gaccatatct aagaaaaaag ggataaagca
     7321 taaaaagtat tctcataaat aacataaata ttgtttctat tatttaagtt gctagacagt
     7381 gaaaagaaaa aatctgtcgt acagtgtcta tatgctcatg tattcaagaa gctacagttt
     7441 tgatttttca taactgtagc ttctttttgt atttattaaa tcacgactat cataatactt
     7501 gcaataggta tagcgacaag agagagtact gtcatatgtg ttttatatat tacattaagt
     7561 atattctaaa atatatgttt taaataatat atttgaaaat aggaatattt aaataaaaaa
     7621 aataatatta tatatagttg acaaaaattg gcaaatgaga taatatataa atatagaaat
     7681 agtaatcatt actattatta aaaagggagg aattaattat gaacttaaaa ggaactaaaa
     7741 cagaaaagaa tttaatggca ggatttgcag gagagtcaga agcaagaaat aaatatacat
     7801 actacgcttc aaaagcaaga aaagaaggtt ataatcaaat agctgctata tttgaagaaa
     7861 ctgctaacaa tgaaaaggaa catgctaaat tatggtttaa acttttacat gatggtatgc
     7921 cttcaacaga ggaaaattta aaggatgcag cagcaggtga aaactatgaa tggactgata
     7981 tgtatgcaaa atttgctaaa gaagctagag aagaaggatt tgacaagata gcttatttat
     8041 ttgaagctgt tggaaaaata gagaaagagc atgaagaaag atacttaaag cttttagaaa
     8101 acttaaatga aggaaaaata tttaaaagag atgaagaagt tgtttggcaa tgtcaaaact
     8161 gtggtcatgt gtatgtaggt actgaagcac cagaaaaatg cccagtatgt gaccatccaa
     8221 aagcgtattt caatataaaa gctgaaaatt attaaaaatt atcattatta aaaaggaatg
     8281 ttaactatga aattttctaa acaacgagaa ctgattttaa atgaaatatt aaataatccg
     8341 gttcatccta ctgcggatta cctatatgaa aacttaaaaa aagataatcc aaatttaagc
     8401 ttaggaactg tgtatagaaa tttagctcag ctaacggaac atggctttat aagaaaggtt
     8461 agtattccag ggtatccaga tagatttgat ggtcgaatag ataatcacta tcatatcata
     8521 tgtgaagtat gtggagaggt atacgattta gaatccgaag ttcttaataa tttacaagaa
     8581 ttaatatctg aggagacaga cataaaaata acatcttata acataagttt taaagggatt
     8641 tgtaataatt gtaaaaggtg tagccaagta ggttagtttt caaattctaa aaataattaa
     8701 tgaggtgagt ttatgtgtag tgaacaaaaa ttttttatat gtgagacttg tggaaacctt
     8761 gtaggaatga tacaaagtgg tggtgtacct attttctgtt gtggaaaacc tatgaaggaa
     8821 cttgttccta atacaacaga tgcagcagtt gaaaaacatg tacctgtaat tgaagtggat
     8881 ggaaataatg ttactgttaa agtaagtagc acaactcatc caatgactaa agaacatcat
     8941 atagcatggg tgtatcttat gactgaacaa ggtggtcaac gcaaatgtct agcagtagat
     9001 ggagaacctg tagttaaatt tgctttgaat gatgatgata aagtgatttc tgcctatgct
     9061 tactgtaatt tacatggatt atggaaggct gaactgtaat atttaaataa attgagtcaa
     9121 aaaggaggct ataaatgtat tttcatacaa atagcctcct ataaatttat ataaattcaa
     9181 gttttaattt tgtttaatgt caatataata taaggagaaa ataatatgtc aatttataaa
     9241 tgtagtgttt gtggatatat ttatgatgaa tctaagaatg ataaaacatg ggatgaatta
     9301 agtgaagatt gggaatgccc tgtatgtaca aaaggtcgta gttattttgg aaagataagt
     9361 actgtttact atgaagaaga tgaaaagata gcagaagaca tagttgaaga tgaatctaaa
     9421 ttaaatactg aaaaagaggg agatttaaat tacttaagta catatttaag aagagatgat
     9481 gaagttgaga aacatatgga tataattcac gaaatggctg ttacaggaaa atctataata
     9541 gaacctatga gaactaaact accagtaatt tcttgggatg atattttaat tatgggtgct
     9601 caattaaatc cattaccttt aaatgagcat gatgaagtaa atacaacaac aataatagga
     9661 aaaaaagcaa agaaacctat gattatagaa aatccagttt atatttccca catgtcattt
     9721 ggagctttgt ctaaagaact aaaaatagct ttagcaaagg gtgcagccca aaataagaca
     9781 gctatgtgta gtggtgaagg aggtatatta ccagaagaga aggaagcttc atacaagtat
     9841 atttttgagt atgtaccaaa taaatatagt gtaactgaag aaaatcttaa aaattctgat
     9901 gctatagaga taaaaattgg tcaaggaaca aaacctggta tgggaggtca tcttcctggc
     9961 gaaaaagtaa ctgaagaaat agcaaaagta agaaataagc ctgtaggtca agatgtaata
    10021 agtccatctt gttttgagga aatacaatcc aaagaagatt taaagaaact tgtagatgaa
    10081 cttagagaag tttcagaagg gcgtccaata ggtgttaaaa tttcagcagg tcatattgaa
    10141 aaagatatgg aatttatagc ttatgctaaa cctgattttg taactattga tggtcgtggt
    10201 ggagctactg gagcaagtcc aaagttgctt aaagatgcaa cttcaattcc aacaatattt
    10261 gctctttatc gtgctagaaa atacatagat acacatggat tagatataga tttggttata
    10321 acaggtgggc ttcgtatatc tactgatttt gctaaggcaa ttgctatggg tgctgatgca
    10381 gttgctattg caagttctgc tcttatggca gcggcgtgtc aacaatatcg tatatgtggt
    10441 tctggtaagt gtcctgtagg agtagctact caggatgagg aattgagaaa aagattacat
    10501 atagaaaaca gtgctaatag agtggcaaac tttttaaatg taagtttaga agaacttaag
    10561 acttttgcta gaatttctgg tcataaagat atacatgatt taagtgttga tgatttatat
    10621 actgttaact ctgaaatatc aaattataca aacatacagc atgtatagat tgaagtttga
    10681 aactattaga ttttagatag ctataaaagt aaatgataaa tatattttat aaaagagagt
    10741 gtcttaaaat gaacttttta gttcataagt cactcttttt tttatgaagc caaatatatt
    10801 tatcatttta gcaatgaaaa agaatcttat ctctttattt tgagatagac tccttctatt
    10861 tatgaaaatt aaagatatta aattgtaaaa tattctgtga tgtcgtacta ttaaactaaa
    10921 gattctgtac tttaaagtaa ataaaaattt aaggagtgat tattatggaa agattgaaga
    10981 tacaagtttt agttgacaat aatacttata ttgatagata ctttgttgga gaaccagcag
    11041 taagctatta tattgagatt gatggaaata ggattttgtt tgactcaggg tattcagatg
    11101 tattcatatc aaacgctgaa aaattaaata tagatttagg aaatttaact catgttgttt
    11161 tttctcatgg gcataatgac catacaagag gtatccagtt tctagaaaat aggtatgatt
    11221 tatctacagt tgaacttatt tcacatccta actgttttat acctagaaaa catggagaga
    11281 aaagcatagg agctccattt tctgctgagg aaattaaaaa tatttttatg tataatccta
    11341 aggataagcc atttaatcta agtaagaatt gtgtgttttt aggtgaaata ccttctataa
    11401 atgattttga aaaaagagct aaaattggta aatgtaaaat aggagatttg tgggaagatg
    11461 attatgtttt agatgattct gctatagttt gtaaaactga taaaggtatt tttattgtta
    11521 caggatgttc tcatagtgga atttgtaata tagtagagta tgctaaaaag gtatgtggag
    11581 atgatagagt tattggtata ctaggtggtt ttcatctttt tgaattgaat aataggttag
    11641 atagtacaat acaatatttg gataaagaag aaatgagaat gttgtaccct tgtcactgtg
    11701 tttcttttaa ggtaaaagcg aagatgaatg aaatattgaa tataaatgaa gttggagtag
    11761 ggctgaccat aagtatatag tatttgaaag tatataagat ttaagttgaa ggtt
//
LOCUS       DAYAOO010000234        10959 bp    DNA     linear   BCT 12-OCT-2024
DEFINITION  TPA_asm: Clostridioides difficile isolate ST8-SSI-h139-18
            SAMN40601845-rid21577343.guided.118, whole genome shotgun sequence.
ACCESSION   DAYAOO010000234 DAYAOO010000000
VERSION     DAYAOO010000234.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN40601845
            Sequence Read Archive: SRR28438827
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 10959)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10959)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-MAY-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-MAY-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002157583.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002157583.1
            Genome Coverage       :: 163x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/11/2024 16:19:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 4,038
            CDSs (total)                      :: 3,963
            Genes (coding)                    :: 3,930
            CDSs (with protein)               :: 3,930
            Genes (RNA)                       :: 75
            rRNAs                             :: 6, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 60
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 33
            CDSs (without protein)            :: 33
            Pseudo Genes (ambiguous residues) :: 0 of 33
            Pseudo Genes (frameshifted)       :: 7 of 33
            Pseudo Genes (incomplete)         :: 25 of 33
            Pseudo Genes (internal stop)      :: 11 of 33
            Pseudo Genes (multiple problems)  :: 8 of 33
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10959
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN40601845-rid21577343.guided.118"
                     /isolate="ST8-SSI-h139-18"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Denmark"
                     /collection_date="2018"
                     /collected_by="Statens Serum Institute"
     gene            246..863
                     /locus_tag="ACGI5H_004017"
     CDS             246..863
                     /locus_tag="ACGI5H_004017"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PepSY domain-containing protein"
                     /protein_id="HFG9699649.1"
                     /translation="MCKKTYLLVVSMLIAGLLTACSGSPTKDSGQAQDNTKKEANASN
                     NALKDEKNNENLMEQDFKVPYTDAINIFKDKYKDADIVDLSLERDLNKFVYTVEGVDD
                     NNEYKMKIDANTKDVLEDKTEKLDSEDLNGVARKEKLDLNDIMTPQQAMEIALKEQNG
                     IVKEWSLDKDLDVTFYKIRIDKDKNEYDIKVDSKKGTVLKVEKED"
     gene            971..3502
                     /locus_tag="ACGI5H_004018"
     CDS             971..3502
                     /locus_tag="ACGI5H_004018"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420250.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-dependent oxidoreductase"
                     /protein_id="HFG9699650.1"
                     /translation="MSLKSLKIKENLYWVGSLDPDLRVFDIIMYTPYGTTYNSYVLKG
                     TEKTVLFETVKDKHFDNYIERLNDLNIDFEKIDYIVVSHTEPDHAGSVEKLLDLAKNA
                     KVVASETAIKYLKEIVNKDFEYVAVTDGDTLSIGDKTLEFFSVPMLHWPDTIYTYIKE
                     DKTLVTCDSFGSHYSNDKIVNTLDENEEKDYLDALRYYYDCIMGPFKPSMVTAIEKIK
                     DLDIDTVCPGHGPVLTENPRKIIDLYYNWSVNEQIKLEKEVTICYVSAHGYTKIMAEA
                     IKAYIEKNSNYKVNLFDVIEHKQEDILAKIAVSQGVLFGTPTILGDALKPIWDILISL
                     NPVLHGGKVASVFGSYGWSGEGIENAMERISQLRMTAVKPFAVNFKPSNEEIDKLYSY
                     TGKFLDKLNSTFGSKKKTKKFKCVICNEVFEGDSAPSVCPVCGAKEDQFIEVEEDEVT
                     FRKDTDEYFVIVGNGAAGFYAADAIRKRNKTCKITMISNEDELTYYRPALSDGINEEL
                     GSDFYMEDKDWYDKNNIVVILGTNVDKLDEVNKTIIVNDGAIKFDKLVIATGSRNFIP
                     PIKGHDLENVFTLRNIKDLYSVKEALEKSKKVVVIGGGLLGLEAAWEFRLKGLEVVVV
                     EAMDSILSKQLDKEGSKILEQCVRDTGIDVRLGVAVDGIEGDGKAQKVVFKDGDSVDC
                     DMVVFSIGVRANTQMVQDTSVKIDRGIVVDKTLQTNVKDIYACGDVAQVGNISLAIWP
                     SSVEMGKIAGANASGDNLTFESEVYPVSLDAMNVKVFSIGNIQNFDKEISSKDEGQRI
                     YKKLFMKDGSLVGAILINDLSCTVKLIRLISEKGDFEDIMKADIL"
     gene            3936..4637
                     /locus_tag="ACGI5H_004019"
     CDS             3936..4637
                     /locus_tag="ACGI5H_004019"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_021418928.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="vancomycin resistance response regulator
                     transcription factor VanR-G-Cd"
                     /protein_id="HFG9699651.1"
                     /translation="MNENILIVDDEKEIADLIEVYLKNEGFTVYKFYTGKEALECIES
                     KNLDMAILDIMLPDIDGFHICQKIREKYYYPIIMLTAKIEDIDKIMGLTIGADDYITK
                     PFNPLEVVARVKTQLRRYMRYNNSYEQQSIIVNEYDIKGLIINKETHKCSLFGKEVAL
                     TPIEFSILWYLCEHQGKVVPSEELFEAVWGEKYLDNNNTVMAHIGRLREKIHEPSKNP
                     KFIKTVWGVGYTIEK"
     gene            4687..5769
                     /gene="vanS"
                     /locus_tag="ACGI5H_004020"
     CDS             4687..5769
                     /gene="vanS"
                     /locus_tag="ACGI5H_004020"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012816161.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="vancomycin resistance histidine kinase VanS"
                     /protein_id="HFG9699652.1"
                     /translation="MRTALMAFIAIIFIWILYSFILYGKFSIWIVSFFENAFRMEYKA
                     ALNLYQQIFRNSMELFMILAMVIVFFIIFRVYLNWFTKYFSEINQGIDSLIKEDVGEV
                     ALSPELLAIEKKINSIKHILEQRKFETQMAEQRKNELIVYLAHDLKTPLTSVIGYLTL
                     LRDESQISEELRKKYLSISLDKAERLEDLINEFFEITRFNLSNISLEYSTVSLTRMLE
                     QLTYEFKPTLMSKNLKYTLNVTPNMMIRCDVNKMQRVFDNLLRNAVYYSFEDTTIEIT
                     AVQEDDYIKLKFINHSNTIPEEKLERIFEQFYRLDTSRNSNSGRAGLGLAIAKEIVEL
                     HNGTITAHSENNIIIFKVIIPIVGNL"
     gene            6030..7130
                     /gene="vanG"
                     /locus_tag="ACGI5H_004021"
     CDS             6030..7130
                     /gene="vanG"
                     /locus_tag="ACGI5H_004021"
                     /EC_number="6.3.2.35"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_021418924.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanine--D-serine ligase VanG"
                     /protein_id="HFG9699653.1"
                     /translation="MNNKKIAVIFGGNSTEYDVSLQSAFAVLENLNTEKYDIIPIGIT
                     REGNWYHYIGDYNNIQNNTWFERDTDIIPVIVSQNRVKNGIIEFLIPDAVSQNHIPNS
                     AIESCENDIKYTKLDFVFPVLHGKNGEDGTVQGLFELAGIQVIGCGTLSSALCMDKDK
                     SHKLVHSEGIKVPKSILLKYSDKFNVAELSKDLTYPLFIKPVRAGSSFGISKIYKKEE
                     LQVAVDLAFEHDNEVIIEENIDGFEVGCAVLGNDDLLVGRVDEIELSKGFFDYTEKYT
                     LKSSKIHMPARIDLDCEKRIQETAKIIYRTLGCSGFARVDMFLTPSGEIIFNEVNTIP
                     GFTSHSRYPNMMKGIGLSFEEILDKIIEVYIK"
     gene            7127..7933
                     /locus_tag="ACGI5H_004022"
     CDS             7127..7933
                     /locus_tag="ACGI5H_004022"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436406.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M15 family metallopeptidase"
                     /protein_id="HFG9699654.1"
                     /translation="MMNNILLDKNKEDKMTNTILLTKDKVYDGNLILVNAFLPVKTSE
                     DIDLIPVDTRFPSILMKREATNILQNILKSICGINEIVPVSGYRTAEEQQDIYSSSLR
                     DNGKDFTKKFVALPNHSEHQTGLAIDLGLKKEVIDFICPEFPYNGICNEFRKAALHYG
                     FIERYQCKKEEITGISQEPWHFRYVGYPHSEIINKMNLALEEYIEYIKRFSYTNCLKI
                     EDKEKIIEIFYVPIHTKEEVRISIPEQCVYQISGNNKDGFIVTFWRNRKD"
     gene            7951..10089
                     /gene="vanT"
                     /locus_tag="ACGI5H_004023"
     CDS             7951..10089
                     /gene="vanT"
                     /locus_tag="ACGI5H_004023"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436408.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016747 - acyltransferase activity,
                     transferring groups other than amino-acyl groups [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="serine racemase VanT catalytic subunit"
                     /protein_id="HFG9699655.1"
                     /translation="MIRNKSYAGLDYFRIIAALLIIAIHTSPLLSYSKMADFVLTSII
                     ARIAVPFFFMLSGFFLISTYNYNCNKLKSFLKNVLFIYGIAIVIYIPLNIYTGYFSMN
                     NLVPNIIKDIVFDGTLYHLWYLPASIIGASIAYFLVKRLGLKYSLVITIVIYVIGMFG
                     DSYYGFLEKIPLLKNLYGYIFEVSDYTRNGIFFAPVFFILGGIISNKSNYMSTKNSLI
                     GFLISFLLMLCEGMFLHKLGVQRHDSMYIMLLPCMYFLFTALTFLKGSRARLLRTSSL
                     IIYIIHPMMIVVIRMFSKIFGIQTVLVDNSLIHYIVVSIASFIASIIIILILKPLKKD
                     LKGEHKVNTNRAWIEIDLNNLEHNVKMIQKAMPEDCELMAVVKANAYGHSAFEVATCA
                     NQIGVKAFAVATIDEGIDLRRYGILGEILILGYTNPIRAKELHKYNLTQSVIDLNHAI
                     SLNKQKYNIKSHIKIDTGMHRLGFDVNDVRSILKAFKLKYLDICGIFTHLCVSDSLKD
                     EDVDFTNKQIECFYKLIDFLLKKGIKIPKVHIQSSYGFFNYPNLKCNYVRIGIALYGI
                     LSSPNDTTKLQLDLRPVLSLKSQVILIRKIQKDDSFGYGRVFIASRDSVIAILSIGYA
                     DGIPRNLSCGKSYVIINGCRAAIVGRICMDQLAVDITDIPNVEVGNTAIIIGRDNLSE
                     LSASEVANNSCSISNELLSRVGRRLNVIKK"
     gene            10403..>10959
                     /locus_tag="ACGI5H_004024"
     CDS             10403..>10959
                     /locus_tag="ACGI5H_004024"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436409.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TVP38/TMEM64 family protein"
                     /protein_id="HFG9699656.1"
                     /translation="MQYIQELLDLTQNYWVLATIIGLLSAFIESFIPALPLVAIVTAN
                     AAIQGLFIGCLLSWIGSGLGTTSLFLLISRFNDSKLFNKLRNSKTEKAISWMDKQGFK
                     LLFIAYACPFMPGCLVTIASAFGKKDLKDFVPAMLAGKFVMFIVISYVASDIEGFITS
                     PLKIASFILLVFLSWKIGNRVNKNL"
BASE COUNT         4145 a         1146 c         1975 g         3693 t
ORIGIN      
        1 caaaatgaac tttttagttc atgaggcact ctttttgtac gaaataaaat atatttttat
       61 tatttcaaca atgaaaaaga ggcttgtttc cattttgaga cagtataatt tttatgtaac
      121 tttaatttta gtaaatataa agttttaaaa ttgataaaat aggaggaatt tttaatataa
      181 aagggtaaat aaagggttta gagggcataa tatagaataa attaatatat ttaaggaggg
      241 tttttatgtg taaaaaaacg tatttattag tggtaagtat gcttatagcg ggtttattaa
      301 ctgcatgtag tgggagtcca actaaggatt caggacaagc acaagataat acaaaaaagg
      361 aggcaaatgc atcaaataac gctttaaaag atgaaaaaaa taatgaaaat ttaatggaac
      421 aagattttaa agtgccatac acagatgcaa taaacatatt taaagataaa tataaggatg
      481 ctgatatagt agatttaagt cttgagagag atttaaataa atttgtttat actgtggaag
      541 gtgtagatga taataatgaa tataagatga aaattgatgc taatacaaaa gatgtattag
      601 aagataaaac agaaaagttg gattcagaag atttaaatgg agttgctaga aaagaaaaat
      661 tagatttaaa tgacataatg acacctcaac aagctatgga aattgcatta aaagaacaaa
      721 atggaatagt taaagaatgg agtttagaca aagatttaga tgttactttt tataaaataa
      781 gaatagataa agataaaaat gaatatgaca taaaagtaga ttctaaaaag ggaactgtat
      841 tgaaggtaga aaaagaagat tagaagattt aaactatctt taaaataatt tcttttttga
      901 ataaattttg tttaaaatat aacaagcagg gtataaagag actaaataac tattttagga
      961 ggagtacggt atgtcattga aatcactaaa aataaaagaa aatttatatt gggtaggttc
     1021 gcttgaccct gatttaagag tatttgacat aattatgtat acaccttatg gaactactta
     1081 taattcatat gtattaaaag gaacagaaaa aacagtttta tttgagacag ttaaagataa
     1141 gcattttgac aattatattg aaagattaaa tgatttaaat atagattttg aaaaaataga
     1201 ctatattgtt gtaagtcata ctgaaccaga ccatgcagga agcgttgaaa agcttttgga
     1261 tttagctaaa aatgcaaaag tagtagcttc agaaacagca attaaatatc ttaaggaaat
     1321 cgtaaacaaa gactttgaat atgttgcagt tacagatgga gatacattat caattgggga
     1381 caaaacttta gaatttttct ctgtacctat gcttcattgg ccagatacca tatacacata
     1441 tataaaagag gataaaactc ttgtaacatg tgattcattt ggtagtcact atagtaatga
     1501 taagatagta aatacacttg atgaaaatga agaaaaggat tacttggatg ctttaagata
     1561 ctattatgat tgtataatgg gtccatttaa accatctatg gtaactgcta tagaaaagat
     1621 aaaagattta gatatagata ctgtatgtcc aggtcatggt ccagtattaa ctgaaaatcc
     1681 tagaaaaatt atagaccttt attacaactg gagtgtaaat gaacaaataa agttagaaaa
     1741 agaagttaca atttgttatg tttctgcaca tggatataca aagattatgg cagaagctat
     1801 aaaagcatat attgaaaaaa atagcaacta taaagtaaat ttatttgatg taatagagca
     1861 taagcaagaa gatattttgg caaaaatagc agtatcacaa ggtgtattat ttggaacacc
     1921 aacaatatta ggagatgcgt taaagcctat atgggatata ttaatatcgt taaacccagt
     1981 tcttcatggt ggaaaagttg cttcagtatt tggttcatat ggatggagtg gagaaggtat
     2041 agaaaatgct atggagagaa taagtcagct tagaatgaca gcagtaaaac cttttgctgt
     2101 taactttaaa ccatcaaatg aagagattga taaattatat tcttatacag gtaaattcct
     2161 agataagtta aattctactt ttggaagtaa aaagaaaact aagaaattta aatgtgtaat
     2221 ttgtaatgaa gtttttgaag gtgatagtgc tcctagtgta tgccctgtat gtggagctaa
     2281 ggaagaccaa tttatagaag ttgaagaaga tgaagttact tttagaaaag atactgatga
     2341 atatttcgta atagtaggaa atggagcagc tggtttttat gcagcagatg ctataagaaa
     2401 aagaaataaa acttgtaaga taactatgat ttctaatgaa gatgagttga cttactatag
     2461 acctgcactt tctgatggta taaatgaaga acttggttca gatttctaca tggaagataa
     2521 agattggtat gataaaaata atatagtagt aatattagga acgaatgtag ataaattaga
     2581 tgaagtgaat aaaactatta tagtgaatga tggagctatt aaatttgata agcttgtaat
     2641 agctacagga agtagaaact ttataccacc aattaagggc catgatttag aaaatgtgtt
     2701 tactcttaga aatataaaag atttatatag tgtaaaagaa gcactagaaa aatctaagaa
     2761 agttgtagtg attggtggcg gtttattggg acttgaagct gcatgggaat ttagactaaa
     2821 aggattagaa gtagtagtag ttgaagccat ggatagcata ctatcaaaac aacttgataa
     2881 agaaggtagt aaaatattag aacaatgtgt aagagataca ggaatagatg taagattggg
     2941 tgtagcagtt gatggtattg aaggtgatgg aaaagctcaa aaagttgtat ttaaagatgg
     3001 agatagtgtc gactgtgata tggtagtatt ttcaattggt gtaagagcaa acactcaaat
     3061 ggttcaggat acatctgtaa aaattgatag aggtattgtt gtagataaga cattacagac
     3121 aaatgttaaa gatatatatg cttgtggaga tgttgcacaa gtgggaaata ttagtttagc
     3181 aatatggcca tcttcagtag aaatgggaaa aatagcaggg gcaaatgcaa gtggagataa
     3241 tttgacattt gaaagtgaag tatatccagt ttcattagat gcaatgaatg taaaagtatt
     3301 tagtattggt aatatacaaa attttgataa agaaatttca tcaaaagatg aaggtcaaag
     3361 aatatataaa aaattattta tgaaagatgg ttcattagtt ggagctatac ttataaatga
     3421 tttaagctgt actgttaaat tgataagatt aatatctgaa aaaggtgatt ttgaggatat
     3481 tatgaaggct gatatactat aatttaaata cattaaaata aaaaggagtt gtctcaaaat
     3541 tgattttttt ctaatcaaat tttaaattca actccttttt tgaattttta tataaaataa
     3601 catggaaatt ttagtaatgt ctgtggttac atacataggt ttaattgttt tttatatgga
     3661 ttgtctctgg tataataaat tgaattgtgt ttgactgata gatattttta ttgaaagtta
     3721 atacctgtta tgcgataata aggacgtgtt aggggagttt ttataataac aattaatctc
     3781 agtttttgtg ttccaatagt agcatcaaca cattctgatg tagtagttct tttcttataa
     3841 aaattagtta caaatatgct tgtaattatt tgatatgtaa atttaccaat attataaatg
     3901 atgacctcga taataaggag agtgaaaaat aatctatgaa cgaaaatatt ttgattgtgg
     3961 atgatgaaaa agaaatagca gatttaattg aagtatattt aaaaaatgaa ggttttacag
     4021 tatacaagtt ttatacaggt aaggaagctc tagaatgtat tgaatctaaa aatttggata
     4081 tggctatttt agatattatg cttcctgata ttgatggatt tcatatttgc cagaaaattc
     4141 gagaaaaata ctattatcct atcattatgt taacagctaa aattgaagat atagacaaga
     4201 taatgggttt aaccataggt gctgatgatt atataacaaa gccatttaac cctttggaag
     4261 ttgttgcaag agtaaagaca caattaagaa gatatatgcg atataataat tcttatgaac
     4321 aacagtcgat aattgttaat gagtatgata ttaaaggatt gattatcaat aaagaaacac
     4381 ataaatgtag tttatttggg aaagaagtag cattaacacc gattgaattt tctattcttt
     4441 ggtatttatg tgaacatcaa ggaaaagtgg ttccttctga agaattgttt gaagctgtat
     4501 ggggagaaaa atatcttgat aataataaca cagttatggc tcatataggg cgattacgtg
     4561 aaaaaattca tgaaccttct aaaaacccga aatttataaa aactgtatgg ggagtaggtt
     4621 atacaattga aaagtaaaaa tattaaagtc aatcctgact ttactcaagt gagaaataaa
     4681 atttttatga gaacagcttt aatggcattt atagccatta ttttcatatg gattttatat
     4741 tcttttatat tgtatggtaa gttttctatc tggatagtat cattctttga aaatgctttt
     4801 cgtatggaat ataaagctgc attgaattta tatcagcaga ttttccgtaa tagcatggag
     4861 ctcttcatga tactagctat ggtgattgtg ttttttataa tattccgggt ttatttaaat
     4921 tggtttacaa aatattttag tgaaataaat caaggtattg actctcttat caaagaagat
     4981 gttggagaag tggctttatc tccagagtta ttggcaatag aaaagaaaat aaactcaatt
     5041 aaacatatac ttgaacaacg taaatttgag acacaaatgg cagaacaacg taagaatgaa
     5101 cttattgttt atcttgcaca tgatttaaaa acaccactta catcagttat agggtatctg
     5161 acactacttc gagatgaaag tcagatttct gaagaactgc gaaaaaaata tttatctatt
     5221 tcgttggata aggcagagcg tcttgaagat ttaattaatg aattctttga aattacaagg
     5281 tttaatttat caaatatatc acttgaatac agtacagtaa gcttaactcg tatgcttgaa
     5341 caactaacat atgagtttaa acctactttg atgagtaaga atttaaaata tacactgaat
     5401 gttacaccaa atatgatgat aaggtgtgat gttaataaaa tgcaacgtgt atttgataac
     5461 ttattacgaa atgctgttta ttatagtttt gaagatacta ctattgaaat aacagctgta
     5521 caggaggatg attatataaa gcttaaattt ataaatcata gcaatacgat tccagaggaa
     5581 aaacttgagc gtatttttga acaattttac aggttggata catctcgtaa ttcaaacagt
     5641 ggtagagctg ggttgggact tgctatagct aaagaaatag tggagcttca taacgggaca
     5701 ataacagctc atagcgagaa caatataatt atctttaagg ttattattcc gattgtagga
     5761 aatttgtaag aatttaagta taaaaaaata ggaaattctt taggataaat aaataaagag
     5821 cactcttgtt attgatataa ttactgtatc aaaacaagag tgcttttatt ttgatacagt
     5881 aattatatca atagaaaaat gtgaaaatat attatgtgga acagatgcaa ttgtaagtga
     5941 aggttgattg gatttgaaat agaaaaagta ttttaacatg tttctgtaga ttgtataaaa
     6001 ataaataaat caacaaagga gaatcaaaga tgaataataa aaaaattgca gttatatttg
     6061 gtggaaactc aacagaatat gatgtatcat tacaatcagc ttttgcagta cttgagaatt
     6121 tgaatacgga aaaatatgat attataccaa ttggaattac aagggagggt aattggtatc
     6181 attatattgg agattataat aatatccaga ataacacttg gtttgaaagg gatactgata
     6241 taattccagt tattgtttcg cagaaccgtg tcaaaaatgg tattattgaa tttttaattc
     6301 ctgatgctgt ttctcagaat catattccaa atagtgctat tgaatcatgt gaaaatgata
     6361 ttaaatacac taaacttgat tttgtgtttc ctgtactgca tggaaaaaat ggagaagatg
     6421 gaacagtgca ggggttattt gaattggcag gtatacaggt tataggatgt ggtactcttt
     6481 cttcagcatt atgtatggac aaagacaaat cacataaact tgttcattca gaaggtatta
     6541 aagtaccaaa atcaatatta ctaaaatact cagataaatt taatgtggct gaactgtcaa
     6601 aagacttaac ttatccatta tttataaaac ctgtgcgtgc aggttcatca tttggtatta
     6661 gtaaaattta taaaaaagaa gagttacaag tagcagtaga cttggctttt gaacatgata
     6721 atgaagtaat aattgaggaa aatattgatg gttttgaggt agggtgtgca gttttaggaa
     6781 acgatgactt acttgttgga agagtagatg aaatagaatt gtcaaaagga ttttttgatt
     6841 atacagaaaa atatacattg aaaagttcaa aaattcatat gccagctaga attgatttgg
     6901 attgtgagaa aagaatacaa gagacagcaa aaattattta tagaactctt ggatgttctg
     6961 gatttgctag agtagatatg tttttaactc catctggtga aattattttt aatgaagtca
     7021 atacaattcc tggctttact tctcatagtc gttatccaaa tatgatgaaa ggtattggat
     7081 tgtcttttga agaaatattg gacaagataa ttgaggtgta cataaaatga tgaataatat
     7141 tttattagat aaaaataaag aagataaaat gacaaatact atcttattga ctaaagataa
     7201 agtttatgat gggaatctaa ttctagtaaa tgctttttta ccagttaaaa catctgaaga
     7261 tatagattta attcctgtag atacaaggtt tccaagtatt cttatgaaac gtgaagctac
     7321 aaacatttta caaaatattt taaaaagtat atgtggaata aatgaaatag tacctgtaag
     7381 tggatatcgt actgcagagg aacaacaaga tatatattca agttctctgc gtgacaatgg
     7441 aaaagacttt actaaaaagt ttgtagcact tccaaatcac agtgaacatc agacagggct
     7501 tgctattgat ttagggttaa agaaagaagt tatagatttt atctgccctg aatttcctta
     7561 taatggtatt tgtaatgagt ttcgtaaggc agcactacat tatggtttta tagagcgtta
     7621 tcagtgtaaa aaagaagaaa taacaggaat atctcaagaa ccatggcatt ttcgttatgt
     7681 gggatatccg cattctgaga ttatcaataa aatgaatctc gctcttgaag aatatataga
     7741 atatattaag agattttcgt atacaaattg tttaaaaata gaagataaag aaaaaattat
     7801 agaaatcttt tatgtgccta ttcatactaa agaagaagtg agaatctcta tacctgaaca
     7861 atgtgtatat caaatatcgg gtaacaataa ggatggtttt attgtgacat tttggagaaa
     7921 tagaaaggac taagaaatgg aggaacaaga atgattagga ataaatctta tgcagggctt
     7981 gattatttta ggattatagc tgcattactt ataattgcaa ttcatacatc tccattatta
     8041 tcatatagta aaatggctga ctttgtgtta actagtataa ttgctcgtat tgctgtgcca
     8101 ttctttttta tgctatcagg cttttttcta atttcaacat ataattataa ttgtaataaa
     8161 ctgaaatctt ttctaaaaaa tgtattattt atttacggga tagctattgt aatttatatt
     8221 cccttaaata tttacactgg atatttttcc atgaataatt tagtgcccaa tattattaag
     8281 gacattgtat ttgatgggac tttatatcat ttatggtatc tacctgcatc aattattggt
     8341 gcaagtattg catactttct tgtaaaaaga ctaggtttaa agtactcact agtaatcact
     8401 attgttattt atgtaattgg tatgtttggt gatagttatt atggtttttt agaaaaaata
     8461 ccactattaa agaatttata tgggtatatt tttgaagtat cagattatac acgaaatggt
     8521 atattttttg cacctgtatt tttcatactt ggtggaataa tatctaataa atctaattat
     8581 atgtcaacta aaaatagctt gattggattt cttatatcat tcttacttat gttatgtgag
     8641 ggaatgtttt tacataaact aggggtacag cgtcatgata gcatgtatat tatgttattg
     8701 ccatgtatgt atttcttatt tacagcctta acatttttga aaggttctcg agctaggtta
     8761 ttgcgaacat catcattaat tatttatatt atacatccta tgatgattgt tgttattcgt
     8821 atgttttcta aaatattcgg aatacaaact gtcttggttg acaatagcct tattcattat
     8881 atagtggtaa gtatagcatc ttttatagct tctataatta ttatattgat tcttaaacct
     8941 ctaaaaaaag acttgaaagg agaacataag gtaaatacca atagagcttg gattgaaatt
     9001 gatttaaata atttggaaca taatgtaaag atgatacaaa aagctatgcc agaagattgt
     9061 gaattgatgg cagttgtaaa agctaatgcc tatggtcata gtgcttttga agtagcgact
     9121 tgtgcaaacc aaataggtgt aaaagcattt gcagtagcaa caatagatga ggggattgat
     9181 ttacgtcgat atggaatact aggagaaata ttgattcttg gatatactaa cccaataagg
     9241 gcaaaggaac ttcataaata caatcttaca cagagtgtta ttgaccttaa tcatgctatc
     9301 tctttaaaca aacagaaata caacataaaa tcacacatta aaattgatac aggtatgcac
     9361 agactgggtt ttgatgttaa tgatgtgagg tcaattttaa aggcatttaa attaaaatac
     9421 ttagatatat gtggcatatt tacacacttg tgtgtttcag atagtctgaa agatgaagat
     9481 gtagacttta caaataaaca aattgaatgt ttttataagt taattgattt tctgttaaaa
     9541 aaaggtataa aaattcctaa agtacatatt caaagtagtt atggtttttt taattatccc
     9601 aatcttaagt gtaattatgt aagaattgga attgcattat acgggatatt aagttctcca
     9661 aatgatacga ctaaattgca acttgattta cgacctgttt tatccttaaa atcacaagta
     9721 attcttatta gaaaaataca aaaagatgat agttttggat atggaagagt ctttattgca
     9781 agcagagata gcgtaattgc tatattatct attggctatg ccgatggtat acctagaaat
     9841 ttatcctgtg gaaaaagtta cgtaataata aatggttgta gagcagcaat agtgggtcga
     9901 atttgcatgg accaacttgc tgttgatatt acagatatac ctaatgtaga agttggtaat
     9961 acggcaataa taataggaag agataattta tctgaattat ctgcttctga agttgcaaat
    10021 aactcatgta gtatatcgaa tgaattattg agcagagtag gaagaaggtt aaatgttata
    10081 aagaagtaac tcaattaaat agtaatattt gttgtactgt gtaatttatt ttactctgac
    10141 tagacatttt tagtaatatt atgtctaata tatatttttt ataacttaca tgacaattta
    10201 agttataaaa aggtgatgtt tcagattttt attttgaaac atcacctttt ttgttataat
    10261 atataataaa ataattatac cttaactgta aacttatata gattatttac tttttaatat
    10321 tagattcatt ttttgagatt ggtatataat aaacatatag agtatataat aatagttaaa
    10381 gttaaaaaag gggaaaagca atatgcagta tatacaagaa ctacttgatt tgactcaaaa
    10441 ttattgggtg ttagccacaa taatcggctt attaagtgca tttatagaaa gctttatacc
    10501 agccttacca cttgttgcta tagttacagc aaatgctgca atacaaggat tatttattgg
    10561 atgtttgtta tcatggattg gctcaggact tgggacaact tcattattct tattaataag
    10621 cagatttaat gatagtaagc tttttaataa gttgagaaat agtaaaactg aaaaagcaat
    10681 aagttggatg gataaacagg gatttaagtt attatttata gcgtatgcct gtccatttat
    10741 gcccggttgt ttagttacta tcgcatcagc ttttggtaaa aaagatttaa aagattttgt
    10801 gccagcaatg ttggcaggaa aatttgtaat gtttatagtt ataagttacg tggcaagtga
    10861 tatagaaggt tttataacaa gtcctttaaa gatagcatca tttatattat tggtgttttt
    10921 gtcatggaag attggaaata gagtaaataa aaatcttga
//
LOCUS       DAYAOO010000235        10370 bp    DNA     linear   BCT 12-OCT-2024
DEFINITION  TPA_asm: Clostridioides difficile isolate ST8-SSI-h139-18
            SAMN40601845-rid21577343.guided.121, whole genome shotgun sequence.
ACCESSION   DAYAOO010000235 DAYAOO010000000
VERSION     DAYAOO010000235.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN40601845
            Sequence Read Archive: SRR28438827
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 10370)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10370)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-MAY-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-MAY-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002157583.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002157583.1
            Genome Coverage       :: 163x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/11/2024 16:19:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 4,038
            CDSs (total)                      :: 3,963
            Genes (coding)                    :: 3,930
            CDSs (with protein)               :: 3,930
            Genes (RNA)                       :: 75
            rRNAs                             :: 6, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 60
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 33
            CDSs (without protein)            :: 33
            Pseudo Genes (ambiguous residues) :: 0 of 33
            Pseudo Genes (frameshifted)       :: 7 of 33
            Pseudo Genes (incomplete)         :: 25 of 33
            Pseudo Genes (internal stop)      :: 11 of 33
            Pseudo Genes (multiple problems)  :: 8 of 33
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10370
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN40601845-rid21577343.guided.121"
                     /isolate="ST8-SSI-h139-18"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Denmark"
                     /collection_date="2018"
                     /collected_by="Statens Serum Institute"
     gene            311..988
                     /locus_tag="ACGI5H_004025"
     CDS             311..988
                     /locus_tag="ACGI5H_004025"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433851.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9699657.1"
                     /translation="MIVIEGSDKFKIAKEYIDVEYTLFSKVTFRYEKLKFKDNAELEK
                     IKMFKYKNGYIPNKLNLSFGYGFSSYKKQIIRETVDTLRLTEIFSSENIEDIKFIKDG
                     TKKLEISIEKVVKFKRRKKRNYVCCYCPDMYRDIKLDKESINKIYNRKIKIEREVNIF
                     EDEDVIINKKVLKFPKSWTKNMQKYWLSENKYPIHSTVIDDDRYKCCNVQYTKNRVII
                     LYYIYNH"
     gene            complement(1316..2083)
                     /gene="aroD"
                     /locus_tag="ACGI5H_004026"
     CDS             complement(1316..2083)
                     /gene="aroD"
                     /locus_tag="ACGI5H_004026"
                     /EC_number="4.2.1.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897376.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003855 - 3-dehydroquinate dehydratase
                     activity [Evidence IEA];
                     GO_process: GO:0009423 - chorismate biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type I 3-dehydroquinate dehydratase"
                     /protein_id="HFG9699658.1"
                     /translation="MKRKVQVKNITIGEGRPKICVPIIGKNKKDIIKEAKELKDACLD
                     IIEWRVDFFENVENIKEVKEVLYELRSYIHDIPLLFTFRSVVEGGEKLISRDYYTTLN
                     KEISNTGLVDLIDVELFMGDEVIDEVVNFAHKKEVKVIISNHDFNKTPKKEEIVSRLC
                     RMQELGADLPKIAVMPQNEKDVLVLLEATNEMFKIYADRPIITMSMSGMGVISRLCGE
                     IFGSALTFGAAKSVSAPGQISFKELNSVLNLLHKSIN"
     gene            complement(2755..3591)
                     /locus_tag="ACGI5H_004027"
                     /pseudo
     CDS             complement(2755..3591)
                     /locus_tag="ACGI5H_004027"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020220015.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
     gene            3662..4330
                     /locus_tag="ACGI5H_004028"
                     /pseudo
     CDS             3662..4330
                     /locus_tag="ACGI5H_004028"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000331151.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
     gene            4457..5077
                     /locus_tag="ACGI5H_004029"
     CDS             4457..5077
                     /locus_tag="ACGI5H_004029"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423956.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_function: GO:0030552 - cAMP binding [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Crp/Fnr family transcriptional regulator"
                     /protein_id="HFG9699659.1"
                     /translation="MHLIDFMNEDIKKKLVKKTYKKKETILFAEQENEYVILMIDGIA
                     EAFILNVKGNISTIHLYRSGSFFGEMEQFNDGKKPVEIVAFTDCNVYKLHRDDFLNWL
                     RGDFEATKFLIREISSKLVVNAELIEELSSLSVKERLLRCISLHYYRSELNLLTKKQL
                     ASEVNAPIRSINRAINECVQEHLIAYENKRFSVINQREVLKNLPTT"
     gene            5233..6015
                     /locus_tag="ACGI5H_004030"
     CDS             5233..6015
                     /locus_tag="ACGI5H_004030"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433844.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoglycoside 6-adenylyltransferase"
                     /protein_id="HFG9699660.1"
                     /translation="MTKTQQKMIQNVLEFSKRDSRIIGLAISSSYITKSLDEYSDLDF
                     LIVADDKSYEEVIEERLLIVEQFGTLVSAFTGEHVGEPRLIISLYDSPVLHVDFKFTT
                     LDGLLDRVEDSAILYEENNCITEIYSKKEAYFPTPDLQWIEDRFWIWVHYACTKIGRR
                     ELFETIDFLSFLRQSVLAPLIQLLLGKLPRGVRKIELDAPQYIEALEKTVANHEYKSC
                     VNALQATINLYLELREELSQSPIVRKVEAERVALQYFQDLIK"
     gene            6140..7066
                     /locus_tag="ACGI5H_004031"
     CDS             6140..7066
                     /locus_tag="ACGI5H_004031"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903090.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFG9699661.1"
                     /translation="MSDILSRITNKIGDKNIVDKLSALSKSDLNSLLLEVFDRQANTL
                     TATDILKSYQLNRFTIPSGIDPEEIHALESKLLRKAFNMDIKTIMLSPSAPLGSCSVF
                     GSVDQYNVVSALRGTETLADPSNMLAIIIADKLKRKEENNTIPIHMATTARVIRAQNF
                     VGKGLYSHFGLYCMVSSGIDTGSYTCEKMLLEKHLNYYKDILSEIENVRFSIILRKRN
                     GYKDNDGFFDRMVETIKLIFPNIELSIHNDDVDNNYYKGINFKLSVKQGNETVEIVDG
                     GFVDWTYQMLGNKRERCLISGIGLERFLVAVS"
     gene            7080..7529
                     /locus_tag="ACGI5H_004032"
                     /pseudo
     CDS             7080..7529
                     /locus_tag="ACGI5H_004032"
                     /inference="COORDINATES: protein motif:HMM:NF024698.4"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:0016746 - acyltransferase activity
                     [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
     gene            7889..8296
                     /locus_tag="ACGI5H_004033"
     CDS             7889..8296
                     /locus_tag="ACGI5H_004033"
                     /inference="COORDINATES: protein motif:HMM:TIGR02937.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_function: GO:0016987 - sigma factor activity [Evidence
                     IEA];
                     GO_process: GO:0006352 - DNA-templated transcription
                     initiation [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-70 family RNA polymerase sigma factor"
                     /protein_id="HFG9699662.1"
                     /translation="MVDEKTIEHQFDSFCKTVLRNYARDIYDENKRRNDYLVSLESLS
                     LAELSKLSILDDYDSNYICMVSYDYNIRIEDVLMAQAIGKLTKRKQDIILLSFFFNMT
                     NADIATLMDLAENTIHYHKTNALKELKELMQEH"
     gene            8298..8528
                     /locus_tag="ACGI5H_004034"
     CDS             8298..8528
                     /locus_tag="ACGI5H_004034"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897394.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HFG9699663.1"
                     /translation="MKPTKEVLPFTIILLAVHGDVNAINVILKHFEHYIIRLSQKTLF
                     DEYGNPYIHVEEETKRMLGTKLITAILRFNLS"
     gene            8918..9121
                     /locus_tag="ACGI5H_004035"
     CDS             8918..9121
                     /locus_tag="ACGI5H_004035"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002262306.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="excisionase"
                     /protein_id="HFG9699664.1"
                     /translation="MNNTDVPIWEKYTLTIEEASKYFRIGEKKLRKRADENLDSGWVI
                     MNSNRIQIKRKQFEKIVDTLDVI"
     gene            9199..9531
                     /locus_tag="ACGI5H_004036"
                     /pseudo
     CDS             9199..9531
                     /locus_tag="ACGI5H_004036"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009271880.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="integrase DNA-binding domain-containing protein"
     gene            9624..10256
                     /locus_tag="ACGI5H_004037"
     CDS             9624..10256
                     /locus_tag="ACGI5H_004037"
                     /EC_number="2.3.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433837.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016746 - acyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0046677 - response to antibiotic [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="CatB-related O-acetyltransferase"
                     /protein_id="HFG9699665.1"
                     /translation="MTIPSSNKVYPRSNDYQTVYLKNVITRENIEVGDYTIYNDFYND
                     PRDFEKNNVLYHYPINNDKLIIGKFCSIACNAKFLMTSGNHSMKSKSTYTFPIFYEEW
                     KLDINHITDAWDNKGNIIIGNDVWIGYDSIIMSGVNIGDGAIIGTRAVVTNDVPPYSI
                     VGGVPAKIIKKRFNNDTISKLLEIKWWDWPYKKIQSNIKHIQSGNIDKLV"
BASE COUNT         3768 a         1495 c         1632 g         3475 t
ORIGIN      
        1 atatattaaa tatttctgca gatgttctta taaaagatat tacttccact ggaaaaacat
       61 atttagaaaa tgatataaat gaagagttaa aagacttaaa ttcaagagaa ctaaatctga
      121 tatcacagat tatagacatc ataaaaaaga ataaaatata attctttata ttttatataa
      181 aaaaaaaggt tatttgaaat aaataacctt tttttgtctt tttgtgttaa cattgtctta
      241 tagtgctaat gagtactatt agaccatgtt ctatggcctt attttaatat aaaacgattg
      301 gagataggct atgattgtga ttgaaggtag cgataaattt aagattgcaa aagaatatat
      361 tgatgtagaa tatactcttt ttagcaaagt aacttttagg tatgaaaagt tgaaatttaa
      421 agataatgct gaattggaaa aaattaagat gtttaaatat aaaaatggct acatccctaa
      481 taaattaaac ctttcttttg gatatggatt ctcttcttat aaaaagcaaa taattagaga
      541 aactgtagat actttaagat tgacagaaat tttttcaagc gagaacatag aagatattaa
      601 atttataaaa gatggtacaa aaaaattaga aattagcata gagaaagttg tgaaatttaa
      661 acgtcgaaaa aaaagaaatt atgtttgttg ctattgccct gatatgtata gagacataaa
      721 actcgacaaa gaatctatca ataagatata caacagaaaa ataaaaatag aaagagaagt
      781 taatattttt gaagatgagg atgttataat aaacaagaaa gtattgaagt ttccaaagtc
      841 ttggacaaag aatatgcaaa aatattggtt aagtgaaaat aagtatccca tacattctac
      901 tgtaattgat gatgatagat ataaatgttg taatgtacaa tatacaaaaa atagagtgat
      961 aatattatat tacatatata accattaata tacataatta caaaaaaata atgacaaata
     1021 tacataatac aaatatatct tctactttag ataaaacagt tattatgaaa acttactatc
     1081 tataaataat agaaatgcta gtataccatc tataatctaa tgtctagtag gttttaatgg
     1141 catattttaa atatgccata gttgatttat aagattttct atatcacttt caaaatacac
     1201 actaaatagt tgcttttcag atataattgc ccaatttaaa ttttactatc tgaaaagttt
     1261 tttatattta atttatatct tcaaaaatac cgtctaatat ttctatataa ttaatttaat
     1321 taatactctt atgtaataga ttaagtactg aatttaactc tttaaatgat atttgccctg
     1381 gtgctgaaac actttttgca gctccaaaag tcaatgcaga accaaatatt tcaccacaca
     1441 atctacttat aacacccatt cctgacattg acattgttat tattggtcta tctgcataaa
     1501 ttttaaacat ttcatttgta gcttcaagta gcactaacac atctttttca ttttgcggca
     1561 taacagctat tttgggtaaa tctgcgccca attcctgcat tctacataaa cgagatacaa
     1621 tctcttcttt ttttggagtt ttattaaaat catgattaga tataattact ttcacttctt
     1681 ttttatgagc aaaattaact acttcatcta tgacctcatc tcccataaat aactctacat
     1741 ctattaaatc tactaaacct gtattagaaa tttctttatt caaagtagta taataatctc
     1801 ttgatattaa tttttctccc ccttctacta cacttctaaa tgtgaataat aaagggatat
     1861 catgtatata acttcttaat tcatagagaa cttccttaac ttctttaata ttttctacat
     1921 tctcaaaaaa atcaactcgc cactctataa tatccaaaca tgcatctttt aactctttag
     1981 cctcttttat aatatctttt ttatttttcc caataattgg tacacaaatt ttaggtctac
     2041 cttctccaat agtaatattt tttacttgaa cttttctttt catattctcc tccataatca
     2101 gaaattctat aggactttaa attctatttt ctgcacaatt taattataca ttaaaaatac
     2161 tatacattat aaaaatacta atttaaaaat aatttttatt ctaattctta aaacaatccc
     2221 acatatttta gaaaaggtac tctataatat acaaacactt cttttttacc taaatttatt
     2281 ttaacatcct ataattttca caatattctt taaattttac tcatataaac aatattattc
     2341 tggatgctaa tagaattaat ctataaatca tagtataatt atgcagaaat aactcgaatt
     2401 tcactactta tgaagagatt gaatattaat gaatctaaat catttgcatt acttaagagt
     2461 tttgactaaa gttgaacacc atacaaaagt agctactcaa ttgtttatac cccaaccaag
     2521 cttaagtaat gttatataga ttctcgaaaa agaatttggt atctttttat ttgaaaaact
     2581 tatattaaat ttgattatct tttcataagt tggtaaatgt cgatatatcc tgtatctaca
     2641 aggagtatcg gcattttctt tttggaagat actttgcata agttggcatt taaccgtata
     2701 agaatgccat caaaagtagt aaataagtag taaactctag tcatactact aggattataa
     2761 ccgttccatt tcagctctcg aagaactaaa tgaaccatgt gcataatagc caagcgtcat
     2821 agtaatgttt ttatgcccca taatatattg caatatatta ggactcattc ctttgttagc
     2881 catatttgta cagagtgtat gcctaaaggt atgtggcgta atctttggta gcttgtcctc
     2941 atgggtctta ttatacttct tgactaacgc tcttaacatg ctttgataat gagttgcttg
     3001 ttttggtaat ccatcttgtt taagaaatag gaagttctgg taaccatcaa caatgattgg
     3061 ttctgcttta gcgttcttac gccgttccac gatacgttca aatgattgat aagctctttc
     3121 agtcattgga atttctcgct taccctgtgt ggtctttgga acttctacat aatagccaat
     3181 cttagtatca ctcaacaatt gatggtctac cataatggct ttatttttca tatccaattc
     3241 taaagtcaaa ccgcataatt cagaaatgcg tagtcctgtt tctaagagga taacaacatc
     3301 atcataatat ttacaataag tcttatcgct ccccataaag gataataagc ccatttcctg
     3361 ttctggtgtt agagcgattt ttggttctgt tgtatcttcc aaaacatcac ttaactaaaa
     3421 attaaatgga ttctttctaa tacagtcgtc ttgaattgcc atgaaaaacg acgctttcag
     3481 tgagcgctta taattgtcaa tggatttata agcacaccca tcttcactca ttcggatagc
     3541 ccagctttta gcgtctgata atttaaccat atcaatgctt tttgcaccta gtgggtcatt
     3601 gatagtatct atattttgat ttataattta tacatttttt taaaaacaga cttttaactg
     3661 taaagaatct atgtataaac ttagctatgt tgtccgtgta tctacaaaga atcttgacga
     3721 gctaaaaagg cgttgtgatg aagtcaaaga cttttacgac gacttatcaa tcaagctcgt
     3781 gcgtcccttt ggggatatgt tgggattgca tggcgaattt attcctgtca gcaaacgtta
     3841 catcaatgat tatattcaat atgtcacttc ggattttttg gctggacttg gttttggagc
     3901 gacacaaacc cttggcgaac atgaggatat ctatcttggc tacaatctgg acactggaaa
     3961 gaatgtctat ctaaaacctg cccttgctag tcaaggggta aagggttcta ttaccaatgc
     4021 gttagcgtct gcgtttatcg gttcattggg tggtggtaaa ttattcagta acaatatgct
     4081 tgtttactat gcggtactat tcggcggaca ggcggtcata gttgacccta aagcagaacg
     4141 cggcaaatgg aaagaaacgc taccagaaat agcccatgag ataaacattg tcaatttaac
     4201 cagtaatgat gaaaacaaag gattgcttga cccttacgtc attttgagcc gtaaaaagga
     4261 ttctgaaagt ttagcgattg atatcctaac attccttact ggtatctcca gtcgtgacag
     4321 tgataagttt ttgcagaaaa atgacaactg gaaaataata atggaatagt ttctatgtaa
     4381 atatattttt actatcttac ctaactaatt gaaagatgat ataatttaat caaagatttg
     4441 gtaaggaggg atgaatatgc atttaattga ttttatgaat gaagatatta aaaagaagct
     4501 tgttaaaaaa acgtataaaa agaaagagac tattcttttt gctgagcaag aaaatgaata
     4561 tgtaattctt atgattgacg gtattgcaga agcattcatc ttaaatgtga aaggaaacat
     4621 ctcaacgatt catctttata gaagtggtag tttttttgga gaaatggaac aatttaatga
     4681 tgggaaaaaa cccgttgaaa ttgtcgcttt cacagattgt aatgtatata aacttcatag
     4741 agatgatttt ttaaactggt taaggggaga ttttgaagct acaaaatttc tgattcgaga
     4801 aatatctagt aaattagttg taaatgctga attaattgaa gaattatcat ctttaagtgt
     4861 taaagaacga cttctgaggt gtatatcctt acactattat agaagtgaat taaatctgct
     4921 taccaaaaaa cagcttgcta gcgaagtaaa cgctccaatt agaagcatta atcgtgctat
     4981 aaatgaatgt gtacaagaac atctaattgc ttatgaaaac aaaagattta gtgtaattaa
     5041 tcagcgagag gtattaaaga atcttcctac aacataagta taatttcaaa aaagtattga
     5101 ataataatta ttcaatgctt ttttatttcg ggtcaagtga cctatttttt tttatttctt
     5161 cattatataa tactcctatg cataattatg ttggattgat agctaataaa agacagtgag
     5221 aggtgttata ttatgactaa aacacaacag aaaatgatac aaaacgtatt agaattttca
     5281 aaaagagata gtaggataat aggacttgca attagcagtt cttatatcac aaaatcgtta
     5341 gatgaatatt ctgatttgga ttttctgatt gtagcagatg ataaatccta tgaagaagtt
     5401 atcgaagaga gattacttat tgtggaacag tttggaacat tagtttctgc ttttactggc
     5461 gaacacgttg gagaacctcg attgataatt tccctctatg attcccctgt tcttcatgtt
     5521 gattttaagt ttacaacctt agatggttta ctagataggg ttgaagattc agctattctc
     5581 tatgaagaaa acaactgcat aacagaaatt tattctaaaa aagaagcata cttcccaact
     5641 ccagacttac agtggattga agatagattt tggatttggg ttcattacgc ttgcactaag
     5701 attggacgta gagaactatt tgaaacaatt gattttttat cttttttaag acaatcagta
     5761 cttgccccat taatacagct tctcttaggt aaattacctc gtggagttag aaaaattgaa
     5821 ttggacgcac cccaatatat tgaagcatta gaaaagacgg ttgctaacca tgaatataaa
     5881 agctgtgtta atgcattgca ggctactatc aacctgtatc ttgagttaag agaggaatta
     5941 tcacaaagtc ctattgtccg aaaggttgaa gctgaaaggg ttgcattaca gtattttcaa
     6001 gatttaatca aataaaccca aagtaaaaaa atattgaata gtaaatattc agtgtttttt
     6061 catttttggt caaatgacct agattagttg ttgtaacaat tctataatta ttttgaaagt
     6121 aacagtatgg aggataacta tgagtgatat tttaagtaga attacaaata aaattgggga
     6181 taagaatata gttgataagt tatcagctct atcaaaatca gatttgaact cacttctatt
     6241 agaagtgttt gatagacaag caaatacttt aactgcaact gatattctaa agtcatacca
     6301 actaaataga tttactatcc ctagcggtat agatccagaa gaaattcatg ctttggaatc
     6361 aaaattattg agaaaagcat tcaatatgga tatcaagacg attatgcttt ctccctctgc
     6421 cccattaggt agctgtagcg tttttggctc cgtagatcaa tataacgtag taagtgctct
     6481 acgagggaca gaaacacttg cagacccctc aaatatgttg gcaataatta ttgctgataa
     6541 attaaaaaga aaagaagaaa ataataccat acctatccac atggctacta ctgctagggt
     6601 aataagagca caaaattttg taggtaaagg tttatattca cattttggct tatattgtat
     6661 ggtttcatct ggtatagata cagggtctta cacttgtgaa aaaatgttgt tagaaaagca
     6721 cttaaactat tataaagata tattaagtga aatagaaaat gttcgtttct ctattattct
     6781 acgcaaaaga aacggataca aagataatga cggatttttc gacagaatgg ttgaaactat
     6841 caaacttatt tttcctaata tagagttatc aattcataat gatgatgttg ataataatta
     6901 ttataaaggt atcaatttca aattatcggt caaacaagga aatgaaaccg ttgaaatagt
     6961 tgacggtgga tttgttgact ggacttatca aatgcttgga aataaaagag aacgctgttt
     7021 gataagtggt attggcttag aaagatttct tgtagctgtt tcataaaagg agaagaaaaa
     7081 tggaacttat agagtggaat tatgcttata ttaccgattt agttgagttt gcgaatgata
     7141 aagaaattgc aaagaatctt cgtgacaact tcccccaccc ttatagggag caaaacgcta
     7201 gagattttgt tagtttttgt ttggcaactt cagatgttaa acaacttagc tatgctattt
     7261 tttatcaaga aagggctatt ggaagtatca gcctaacatt tgaagaagat acctctatta
     7321 ataaaaatgc tgaattaggt tactggcttg ctaggaacta ttgaggcaaa gggatagcaa
     7381 caaatgcagt aaaagaaata tgcaaaattg cctttgaaaa atacaacctt aacaaaattc
     7441 atgctaatgt atattcctac aatagagagt caagtaaagt attggaaaaa tgtggcttta
     7501 agattgaaga atactgtcac aattcataat aaagaataga aacatgattg attgccatgt
     7561 atatagttta attcgaccgc aatagcattt attagaatta acctactttt taataacaga
     7621 ataagttttt cccctctatt aatttcttat gcatctttgt atttttatga aaagctagcc
     7681 aatgcatatt tccatacatc aatatggtgg tggcttacaa ccaatataaa ttaaatacgt
     7741 tttaaagaat acacattttt gccctatagg cagagtgtgt atttttttct cttttttttg
     7801 aaatttatcg aagatttaac gccctcccac cgtgatagga gtaagcaagg ttatttaact
     7861 ccttgcgatg gaaagagggt gaaatcttat ggttgatgaa aagacaattg aacatcaatt
     7921 cgacagtttc tgtaaaacag ttttgcgtaa ctatgctaga gatatttatg acgaaaataa
     7981 acgcagaaat gattatttgg tatctctcga atctttgtca cttgcagaat taagtaaatt
     8041 gagtatttta gatgattatg attctaacta catctgtatg gtttcttacg actacaacat
     8101 acgaattgaa gatgtattaa tggcgcaagc aatcggaaaa cttacaaaaa gaaaacaaga
     8161 tataattcta ctttcattct ttttcaacat gacaaatgct gacatagcaa cattgatgga
     8221 tttagcagaa aataccatac attatcacaa aacaaatgca ctaaaagagt tgaaagaact
     8281 catgcaggaa cattgaaatg aaacctacta aagaagtatt accttttaca attattttac
     8341 ttgctgtaca tggcgatgta aatgcaataa acgtaatact taaacatttt gaacactata
     8401 tcattcgtct ttcacagaaa actttatttg atgaatacgg aaatccctat attcatgtag
     8461 aagaagaaac aaagcgaatg ctaggaacaa aactaatcac tgctattttg agatttaatt
     8521 tgtcttaatc tcgccctctc tccatgtatc aagctatttg gtacatggag aatcactaat
     8581 tatttgtcta taaaagccca caagctattg tgatttttta taggcaaatc aatgccgact
     8641 gttctttgac aactgaataa agtagataga tacgtttgtg atacagatag ccaacaaata
     8701 ctatacgcca tgaccttaat caagagagct actatatagt gatttgtgaa taacctttgg
     8761 aacggttgtt ttgccgtaac ctgtaccaca gtataatgat acacctgtat gacacggttc
     8821 tgtccataag aatgggattg gttgaaatac caatggagct tatcaaagcc atctatctac
     8881 ttctgaacta cgaacataga aaggagtgat acattatatg aacaatactg atgtacctat
     8941 ttgggaaaaa tataccttga cgattgaaga agcgtcaaaa tactttcgta ttggagagaa
     9001 aaaattacgt aaacgtgctg atgaaaacct tgattctggc tgggtcatta tgaatagcaa
     9061 tcgcattcaa ataaagagaa aacaatttga gaaaatcgtt gatacacttg acgttatcta
     9121 atgaaattga gccttatatg ttataatatt catatgacgt atcaagctca attcggttat
     9181 tgagaggagc ttcttatcat gtcaactgaa aaaagacgag ataataaaga tagaatttta
     9241 agaactggag agagccagag aaaagatgga agatacgcat ataagtatgt atattcattt
     9301 ggtaaaccac aatttgttta ctcttggaaa cttgtaccta ctgataaacc cccaaaggga
     9361 aaacgtgatg atatatcatt aagggataag gaaaaagcaa tacaaaatga ccttgatgat
     9421 agcattgaca ctattggtaa gaaaatgaca gtttgtcagt tatacgctaa aaagaatgga
     9481 ctaagaaaga atatccgact taacactaaa aaaggacgcc attatcttat gaagattctt
     9541 aacaaggagt gattctgtga agagatgtat tgtagtagtg gaatagtcaa aaacataata
     9601 tatattaaag gagagattta aatatgacta ttccaagttc aaataaggta tatccaagaa
     9661 gtaatgatta tcaaactgta tatcttaaaa atgtaataac aagggaaaat atagaagttg
     9721 gagattacac aatatataat gacttttata atgacccaag agattttgag aaaaacaatg
     9781 tattgtatca ttaccctata aacaatgata aattaataat tggtaagttt tgctcaatag
     9841 catgtaatgc aaaatttcta atgactagtg gaaatcactc aatgaaatca aaatccacat
     9901 atacttttcc catcttttat gaagaatgga aactcgatat caaccatata acggacgctt
     9961 gggacaataa gggtaacatt ataattggaa atgatgtgtg gataggttat gattctataa
    10021 ttatgtcagg tgtaaatatt ggtgatggtg caattattgg aacaagagca gtagttacta
    10081 atgacgttcc accgtattct attgttggag gagtacctgc aaaaattata aaaaagagat
    10141 ttaataatga tacaatttca aaattattag aaattaaatg gtgggattgg ccatataaaa
    10201 aaattcaatc aaacattaag catattcaat caggaaatat tgataaatta gtttaatatt
    10261 ttataattta tttatattaa actttacttt aataatcatt ttataagagc tttttcaaaa
    10321 tttgtatatt attttaatat atataaattt aatacaacat taaataaaat
//
LOCUS       DAYAOO010000236         1524 bp    DNA     linear   BCT 12-OCT-2024
DEFINITION  TPA_asm: Clostridioides difficile isolate ST8-SSI-h139-18
            SAMN40601845-rid21577343.guided.203, whole genome shotgun sequence.
ACCESSION   DAYAOO010000236 DAYAOO010000000
VERSION     DAYAOO010000236.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN40601845
            Sequence Read Archive: SRR28438827
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 1524)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1524)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-MAY-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-MAY-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002157583.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002157583.1
            Genome Coverage       :: 163x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/11/2024 16:19:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 4,038
            CDSs (total)                      :: 3,963
            Genes (coding)                    :: 3,930
            CDSs (with protein)               :: 3,930
            Genes (RNA)                       :: 75
            rRNAs                             :: 6, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 60
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 33
            CDSs (without protein)            :: 33
            Pseudo Genes (ambiguous residues) :: 0 of 33
            Pseudo Genes (frameshifted)       :: 7 of 33
            Pseudo Genes (incomplete)         :: 25 of 33
            Pseudo Genes (internal stop)      :: 11 of 33
            Pseudo Genes (multiple problems)  :: 8 of 33
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1524
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN40601845-rid21577343.guided.203"
                     /isolate="ST8-SSI-h139-18"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Denmark"
                     /collection_date="2018"
                     /collected_by="Statens Serum Institute"
     gene            278..1231
                     /gene="blaCDD"
                     /locus_tag="ACGI5H_004038"
     CDS             278..1231
                     /gene="blaCDD"
                     /locus_tag="ACGI5H_004038"
                     /EC_number="3.5.2.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434692.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008658 - penicillin binding [Evidence
                     IEA];
                     GO_function: GO:0008800 - beta-lactamase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="CDD family class D beta-lactamase"
                     /protein_id="HFG9699666.1"
                     /translation="MKRKKNFIWIAILLVGVVMVMYYVGKKHNDINQKTDKNYIKSEL
                     NKSELNKSKIENNNKNKKEKINMVDYSDCFEGISGGAIFYNTKNKEYNIYNKELIETR
                     RSPCSTFKIVSTLIGLEKGVINSKESVMGYDGTEYPNKNWNKNLSLEEAFKESCVWYY
                     KKLIDKVDAKSVQNILDDLKYGNCDISEWEGDLKNGKGHLNGFWLESSLQISPKEQVQ
                     TMAKIFEGDTNFKKEHINILRDIMKIDVNDKNINVYGKTGTGFDEKNKRVDAWFVGML
                     EREGDTYYFAIKSDDSNKEITGPKVKEIAINIIKKYYSVRE"
BASE COUNT          647 a          121 c          242 g          514 t
ORIGIN      
        1 attgtaatat ttaaatatta caatagtaag ttttaaatgt ggaatcaatt attatatcac
       61 aaattaaaag gaggacagga tgttattaat agttacttaa ttatcttcgc aataggttta
      121 atcaacataa ttgtactagg tgaagaaaat ataagagata cagctattca tttagtcttg
      181 tttcttataa gtagaaccta gattggagta tattacaaat aatgtctact attttaatag
      241 taggttataa atttaaatat gggagatgat ataaattatg aaaagaaaaa agaattttat
      301 ttggatagct atcttattgg ttggtgtagt tatggtaatg tattatgtag ggaaaaaaca
      361 taacgatata aatcaaaaaa ctgataagaa ttatataaaa tctgaattaa ataagtctga
      421 attaaataaa tccaaaattg aaaacaataa taaaaacaaa aaagaaaaaa ttaatatggt
      481 tgactatagt gattgttttg aaggtattag tggaggagct attttttata atactaaaaa
      541 taaagaatat aatatatata acaaagaatt aattgaaaca agaaggtcac catgttctac
      601 ttttaaaata gtttcaactt taattggttt agaaaaaggg gtaataaact caaaagaatc
      661 agttatggga tatgatggta cagagtatcc aaataaaaat tggaataaaa atcttagttt
      721 agaagaggca tttaaggagt cttgtgtttg gtactacaaa aaattgatag ataaagttga
      781 tgctaaatct gtccaaaaca ttttagatga tttaaagtat gggaattgcg atattagcga
      841 atgggaagga gatttaaaaa atggaaaggg acatttaaat ggattttggt tagaatcttc
      901 attacaaata tctccaaaag aacaagtgca aacaatggca aaaatatttg agggagatac
      961 aaactttaaa aaagagcata ttaatatttt aagagatatt atgaaaatag atgtaaatga
     1021 taaaaacata aatgtatatg gaaaaactgg aacaggattt gatgaaaaaa ataaacgtgt
     1081 ggatgcatgg tttgttggta tgctagagcg tgaaggtgac acctattatt ttgctattaa
     1141 atcagatgat tccaataaag aaattacagg gccaaaggta aaggaaattg caattaatat
     1201 aattaagaaa tattatagtg taagggaata aacttaattt tatttgtaaa tattatttac
     1261 ctatagtctg taatatttat taaataattt tactaaattg agtctatata gagcaaaact
     1321 cctttagtac ataaaatact tgctattgat tattaaattg aatacctata gatttaaagt
     1381 taataccttt taaagactat gtaatatatt aaaagtataa ataaaatata ttgcatagtt
     1441 tttgttttat attataattt taaataatgt gcaaaaacta aacaatattt ttaatagtaa
     1501 tttatatttg tattcatgtc acta
//
